data_9G89
# 
_entry.id   9G89 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9G89         pdb_00009g89 10.2210/pdb9g89/pdb 
WWPDB D_1292140529 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9G89 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          9G88 
_pdbx_database_related.content_type   unspecified 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 jacek.plewka@uj.edu.pl       Jacek     Plewka         ? 'principal investigator/group leader' 0000-0002-0307-0907 
3 lukas.schober@tugraz.at      Lukas     Schober        ? 'principal investigator/group leader' 0000-0001-6546-6555 
4 k.magiera@uj.edu.pl          Katarzyna Magiera-Mularz ? 'principal investigator/group leader' 0000-0002-4826-6380 
5 florian.rudroff@tuwien.ac.at Florian   Rudroff        ? 'principal investigator/group leader' 0000-0002-6680-8200 
6 margit.winkler@tugraz.at     Margit    Winkler        ? 'principal investigator/group leader' 0000-0002-0754-9704 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Plewka, J.'         1 0000-0002-0307-0907 
'Schober, L.'        2 0000-0001-6546-6555 
'Magiera-Mularz, K.' 3 0000-0002-4826-6380 
'Rudroff, F.'        4 0000-0002-6680-8200 
'Winkler, M.'        5 0000-0002-0754-9704 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'structure of carotenoid cleavage oxygenase from Moesziomyces aphidis in apo and product bound forms' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.5c00456 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Schober, L.'        1 ? 
primary 'Plewka, J.'         2 ? 
primary 'Magiera-Mularz, K.' 3 ? 
primary 'Rudroff, F.'        4 ? 
primary 'Winkler, M.'        5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Lignostilbene dioxygenase'     62905.562 2   ? ? ? 'Aromatic dioxygenase' 
2 non-polymer syn 4-hydroxy-3-methoxybenzaldehyde 152.147   2   ? ? ? ?                      
3 non-polymer syn GLYCEROL                        92.094    6   ? ? ? ?                      
4 non-polymer syn 'FE (II) ION'                   55.845    2   ? ? ? ?                      
5 water       nat water                           18.015    893 ? ? ? ?                      
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Carotenoid cleavage oxygenase, Aromatic dioxygenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 4-hydroxy-3-methoxybenzaldehyde V55 
3 GLYCEROL                        GOL 
4 'FE (II) ION'                   FE2 
5 water                           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   TRP n 
1 3   SER n 
1 4   HIS n 
1 5   PRO n 
1 6   GLN n 
1 7   PHE n 
1 8   GLU n 
1 9   LYS n 
1 10  ALA n 
1 11  PRO n 
1 12  THR n 
1 13  ALA n 
1 14  THR n 
1 15  GLN n 
1 16  GLU n 
1 17  PRO n 
1 18  VAL n 
1 19  PRO n 
1 20  VAL n 
1 21  PRO n 
1 22  VAL n 
1 23  THR n 
1 24  SER n 
1 25  LYS n 
1 26  ALA n 
1 27  ALA n 
1 28  PRO n 
1 29  SER n 
1 30  HIS n 
1 31  GLY n 
1 32  TYR n 
1 33  VAL n 
1 34  HIS n 
1 35  PRO n 
1 36  THR n 
1 37  ASP n 
1 38  ILE n 
1 39  LEU n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  TRP n 
1 44  PRO n 
1 45  THR n 
1 46  ALA n 
1 47  THR n 
1 48  ASP n 
1 49  LEU n 
1 50  SER n 
1 51  GLY n 
1 52  GLY n 
1 53  ALA n 
1 54  GLN n 
1 55  PRO n 
1 56  ARG n 
1 57  ARG n 
1 58  PHE n 
1 59  GLU n 
1 60  GLY n 
1 61  THR n 
1 62  ILE n 
1 63  PHE n 
1 64  ASP n 
1 65  VAL n 
1 66  MET n 
1 67  THR n 
1 68  ARG n 
1 69  GLY n 
1 70  THR n 
1 71  ILE n 
1 72  PRO n 
1 73  LYS n 
1 74  GLU n 
1 75  LEU n 
1 76  HIS n 
1 77  GLY n 
1 78  THR n 
1 79  PHE n 
1 80  TYR n 
1 81  ARG n 
1 82  ILE n 
1 83  MET n 
1 84  PRO n 
1 85  ASP n 
1 86  TYR n 
1 87  ALA n 
1 88  GLN n 
1 89  PRO n 
1 90  PRO n 
1 91  THR n 
1 92  TYR n 
1 93  TYR n 
1 94  LYS n 
1 95  GLY n 
1 96  GLY n 
1 97  GLU n 
1 98  LEU n 
1 99  ASN n 
1 100 ALA n 
1 101 PRO n 
1 102 ILE n 
1 103 ASP n 
1 104 GLY n 
1 105 ASP n 
1 106 GLY n 
1 107 THR n 
1 108 VAL n 
1 109 ALA n 
1 110 ALA n 
1 111 PHE n 
1 112 ARG n 
1 113 PHE n 
1 114 LYS n 
1 115 ASP n 
1 116 GLY n 
1 117 LYS n 
1 118 VAL n 
1 119 ASP n 
1 120 TYR n 
1 121 ARG n 
1 122 GLN n 
1 123 ARG n 
1 124 PHE n 
1 125 VAL n 
1 126 GLU n 
1 127 THR n 
1 128 ASP n 
1 129 ARG n 
1 130 PHE n 
1 131 LYS n 
1 132 VAL n 
1 133 GLU n 
1 134 ARG n 
1 135 ARG n 
1 136 ALA n 
1 137 ARG n 
1 138 LYS n 
1 139 SER n 
1 140 MET n 
1 141 TYR n 
1 142 GLY n 
1 143 LEU n 
1 144 TYR n 
1 145 ARG n 
1 146 ASN n 
1 147 PRO n 
1 148 TYR n 
1 149 THR n 
1 150 HIS n 
1 151 HIS n 
1 152 PRO n 
1 153 CYS n 
1 154 VAL n 
1 155 ARG n 
1 156 GLN n 
1 157 THR n 
1 158 VAL n 
1 159 GLU n 
1 160 SER n 
1 161 THR n 
1 162 ALA n 
1 163 ASN n 
1 164 THR n 
1 165 ASN n 
1 166 VAL n 
1 167 VAL n 
1 168 MET n 
1 169 HIS n 
1 170 ALA n 
1 171 GLY n 
1 172 ARG n 
1 173 PHE n 
1 174 LEU n 
1 175 ALA n 
1 176 MET n 
1 177 LYS n 
1 178 GLU n 
1 179 ASN n 
1 180 GLY n 
1 181 ASN n 
1 182 ALA n 
1 183 TYR n 
1 184 GLU n 
1 185 MET n 
1 186 ASP n 
1 187 PRO n 
1 188 HIS n 
1 189 THR n 
1 190 LEU n 
1 191 LYS n 
1 192 THR n 
1 193 LEU n 
1 194 GLY n 
1 195 TYR n 
1 196 ASN n 
1 197 PRO n 
1 198 PHE n 
1 199 ASN n 
1 200 LEU n 
1 201 PRO n 
1 202 SER n 
1 203 LYS n 
1 204 THR n 
1 205 MET n 
1 206 THR n 
1 207 ALA n 
1 208 HIS n 
1 209 PRO n 
1 210 LYS n 
1 211 GLN n 
1 212 CYS n 
1 213 SER n 
1 214 VAL n 
1 215 THR n 
1 216 GLY n 
1 217 ASN n 
1 218 LEU n 
1 219 VAL n 
1 220 GLY n 
1 221 PHE n 
1 222 GLY n 
1 223 TYR n 
1 224 GLU n 
1 225 ALA n 
1 226 LYS n 
1 227 GLY n 
1 228 LEU n 
1 229 ALA n 
1 230 THR n 
1 231 LYS n 
1 232 ASP n 
1 233 VAL n 
1 234 TYR n 
1 235 TYR n 
1 236 PHE n 
1 237 GLU n 
1 238 VAL n 
1 239 ASP n 
1 240 PRO n 
1 241 SER n 
1 242 GLY n 
1 243 LYS n 
1 244 VAL n 
1 245 VAL n 
1 246 ARG n 
1 247 ASP n 
1 248 LEU n 
1 249 TRP n 
1 250 LEU n 
1 251 GLU n 
1 252 ALA n 
1 253 PRO n 
1 254 TRP n 
1 255 CYS n 
1 256 ALA n 
1 257 PHE n 
1 258 ILE n 
1 259 HIS n 
1 260 ASP n 
1 261 CYS n 
1 262 ALA n 
1 263 LEU n 
1 264 THR n 
1 265 PRO n 
1 266 ASN n 
1 267 TYR n 
1 268 LEU n 
1 269 VAL n 
1 270 LEU n 
1 271 MET n 
1 272 LEU n 
1 273 TRP n 
1 274 PRO n 
1 275 PHE n 
1 276 GLU n 
1 277 ALA n 
1 278 ASN n 
1 279 LEU n 
1 280 GLU n 
1 281 ARG n 
1 282 MET n 
1 283 LYS n 
1 284 ALA n 
1 285 GLY n 
1 286 GLY n 
1 287 HIS n 
1 288 HIS n 
1 289 TRP n 
1 290 ALA n 
1 291 TYR n 
1 292 ASP n 
1 293 TYR n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 ILE n 
1 298 THR n 
1 299 TRP n 
1 300 ILE n 
1 301 THR n 
1 302 ILE n 
1 303 PRO n 
1 304 ARG n 
1 305 GLY n 
1 306 ALA n 
1 307 LYS n 
1 308 SER n 
1 309 LYS n 
1 310 ASP n 
1 311 GLU n 
1 312 VAL n 
1 313 LYS n 
1 314 TYR n 
1 315 TRP n 
1 316 HIS n 
1 317 TRP n 
1 318 LYS n 
1 319 ASN n 
1 320 GLY n 
1 321 MET n 
1 322 PRO n 
1 323 ILE n 
1 324 HIS n 
1 325 THR n 
1 326 ALA n 
1 327 SER n 
1 328 GLY n 
1 329 PHE n 
1 330 GLU n 
1 331 ASP n 
1 332 GLU n 
1 333 GLN n 
1 334 GLY n 
1 335 ARG n 
1 336 ILE n 
1 337 ILE n 
1 338 ILE n 
1 339 ASP n 
1 340 SER n 
1 341 SER n 
1 342 LEU n 
1 343 VAL n 
1 344 HIS n 
1 345 GLY n 
1 346 ASN n 
1 347 ALA n 
1 348 PHE n 
1 349 PRO n 
1 350 PHE n 
1 351 PHE n 
1 352 PRO n 
1 353 PRO n 
1 354 ASP n 
1 355 SER n 
1 356 ASP n 
1 357 GLU n 
1 358 GLN n 
1 359 LYS n 
1 360 LYS n 
1 361 LYS n 
1 362 GLN n 
1 363 GLU n 
1 364 ALA n 
1 365 ASP n 
1 366 GLY n 
1 367 THR n 
1 368 PRO n 
1 369 LYS n 
1 370 ALA n 
1 371 GLN n 
1 372 PHE n 
1 373 VAL n 
1 374 ARG n 
1 375 TRP n 
1 376 THR n 
1 377 ILE n 
1 378 ASP n 
1 379 PRO n 
1 380 ARG n 
1 381 LYS n 
1 382 ASP n 
1 383 ASN n 
1 384 ASN n 
1 385 GLU n 
1 386 GLN n 
1 387 LEU n 
1 388 PRO n 
1 389 ASP n 
1 390 PRO n 
1 391 GLU n 
1 392 VAL n 
1 393 ILE n 
1 394 LEU n 
1 395 ASP n 
1 396 THR n 
1 397 PRO n 
1 398 SER n 
1 399 GLU n 
1 400 PHE n 
1 401 PRO n 
1 402 GLN n 
1 403 ILE n 
1 404 ASP n 
1 405 ASN n 
1 406 ARG n 
1 407 PHE n 
1 408 MET n 
1 409 GLY n 
1 410 VAL n 
1 411 GLU n 
1 412 TYR n 
1 413 SER n 
1 414 SER n 
1 415 ALA n 
1 416 PHE n 
1 417 ILE n 
1 418 ASN n 
1 419 VAL n 
1 420 PHE n 
1 421 VAL n 
1 422 PRO n 
1 423 ASP n 
1 424 ARG n 
1 425 SER n 
1 426 ASP n 
1 427 GLY n 
1 428 ASN n 
1 429 LYS n 
1 430 ASN n 
1 431 VAL n 
1 432 PHE n 
1 433 GLN n 
1 434 GLY n 
1 435 LEU n 
1 436 ASN n 
1 437 GLY n 
1 438 LEU n 
1 439 ALA n 
1 440 HIS n 
1 441 TYR n 
1 442 LYS n 
1 443 ARG n 
1 444 LYS n 
1 445 GLU n 
1 446 GLY n 
1 447 THR n 
1 448 THR n 
1 449 GLU n 
1 450 TRP n 
1 451 TYR n 
1 452 TYR n 
1 453 ALA n 
1 454 GLY n 
1 455 ASP n 
1 456 ASN n 
1 457 CYS n 
1 458 LEU n 
1 459 ILE n 
1 460 GLN n 
1 461 GLU n 
1 462 PRO n 
1 463 VAL n 
1 464 PHE n 
1 465 SER n 
1 466 PRO n 
1 467 ARG n 
1 468 SER n 
1 469 LYS n 
1 470 ASP n 
1 471 ALA n 
1 472 PRO n 
1 473 GLU n 
1 474 GLY n 
1 475 ASP n 
1 476 GLY n 
1 477 PHE n 
1 478 VAL n 
1 479 LEU n 
1 480 ALA n 
1 481 ILE n 
1 482 VAL n 
1 483 ASP n 
1 484 ARG n 
1 485 LEU n 
1 486 ASP n 
1 487 LEU n 
1 488 ASN n 
1 489 ARG n 
1 490 SER n 
1 491 GLU n 
1 492 VAL n 
1 493 VAL n 
1 494 VAL n 
1 495 ILE n 
1 496 ASP n 
1 497 THR n 
1 498 ARG n 
1 499 ASP n 
1 500 PHE n 
1 501 THR n 
1 502 LYS n 
1 503 ALA n 
1 504 VAL n 
1 505 ALA n 
1 506 ALA n 
1 507 VAL n 
1 508 GLN n 
1 509 LEU n 
1 510 PRO n 
1 511 PHE n 
1 512 ALA n 
1 513 ILE n 
1 514 ARG n 
1 515 SER n 
1 516 GLY n 
1 517 ILE n 
1 518 HIS n 
1 519 GLY n 
1 520 GLN n 
1 521 TRP n 
1 522 ILE n 
1 523 PRO n 
1 524 GLY n 
1 525 GLU n 
1 526 VAL n 
1 527 THR n 
1 528 PRO n 
1 529 ASP n 
1 530 PHE n 
1 531 GLU n 
1 532 THR n 
1 533 LYS n 
1 534 GLY n 
1 535 LEU n 
1 536 VAL n 
1 537 ASP n 
1 538 LEU n 
1 539 PRO n 
1 540 LYS n 
1 541 GLU n 
1 542 GLU n 
1 543 HIS n 
1 544 TRP n 
1 545 ALA n 
1 546 PRO n 
1 547 LEU n 
1 548 SER n 
1 549 GLN n 
1 550 SER n 
1 551 PRO n 
1 552 TYR n 
1 553 ASP n 
1 554 PRO n 
1 555 ASP n 
1 556 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   556 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PaG_05861 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Moesziomyces aphidis' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     84754 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                         ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                        ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                      ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                 ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                        ?                               'C3 H7 N O2 S'   121.158 
FE2 non-polymer         . 'FE (II) ION'                   ?                               'Fe 2'           55.845  
GLN 'L-peptide linking' y GLUTAMINE                       ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                 ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                         ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                        'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                       ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                           ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                      ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                         ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                          ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                      ?                               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                   ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                         ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                          ?                               'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                       ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                      ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                        ?                               'C9 H11 N O3'    181.189 
V55 non-polymer         . 4-hydroxy-3-methoxybenzaldehyde p-vanillin                      'C8 H8 O3'       152.147 
VAL 'L-peptide linking' y VALINE                          ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -7  ?   ?   ?   A . n 
A 1 2   TRP 2   -6  ?   ?   ?   A . n 
A 1 3   SER 3   -5  ?   ?   ?   A . n 
A 1 4   HIS 4   -4  ?   ?   ?   A . n 
A 1 5   PRO 5   -3  ?   ?   ?   A . n 
A 1 6   GLN 6   -2  ?   ?   ?   A . n 
A 1 7   PHE 7   -1  ?   ?   ?   A . n 
A 1 8   GLU 8   0   ?   ?   ?   A . n 
A 1 9   LYS 9   1   ?   ?   ?   A . n 
A 1 10  ALA 10  2   ?   ?   ?   A . n 
A 1 11  PRO 11  3   ?   ?   ?   A . n 
A 1 12  THR 12  4   ?   ?   ?   A . n 
A 1 13  ALA 13  5   ?   ?   ?   A . n 
A 1 14  THR 14  6   ?   ?   ?   A . n 
A 1 15  GLN 15  7   ?   ?   ?   A . n 
A 1 16  GLU 16  8   ?   ?   ?   A . n 
A 1 17  PRO 17  9   ?   ?   ?   A . n 
A 1 18  VAL 18  10  ?   ?   ?   A . n 
A 1 19  PRO 19  11  ?   ?   ?   A . n 
A 1 20  VAL 20  12  ?   ?   ?   A . n 
A 1 21  PRO 21  13  ?   ?   ?   A . n 
A 1 22  VAL 22  14  ?   ?   ?   A . n 
A 1 23  THR 23  15  ?   ?   ?   A . n 
A 1 24  SER 24  16  ?   ?   ?   A . n 
A 1 25  LYS 25  17  ?   ?   ?   A . n 
A 1 26  ALA 26  18  ?   ?   ?   A . n 
A 1 27  ALA 27  19  ?   ?   ?   A . n 
A 1 28  PRO 28  20  ?   ?   ?   A . n 
A 1 29  SER 29  21  ?   ?   ?   A . n 
A 1 30  HIS 30  22  ?   ?   ?   A . n 
A 1 31  GLY 31  23  ?   ?   ?   A . n 
A 1 32  TYR 32  24  32  TYR TYR A . n 
A 1 33  VAL 33  25  33  VAL VAL A . n 
A 1 34  HIS 34  26  34  HIS HIS A . n 
A 1 35  PRO 35  27  35  PRO PRO A . n 
A 1 36  THR 36  28  36  THR THR A . n 
A 1 37  ASP 37  29  37  ASP ASP A . n 
A 1 38  ILE 38  30  38  ILE ILE A . n 
A 1 39  LEU 39  31  39  LEU LEU A . n 
A 1 40  PRO 40  32  40  PRO PRO A . n 
A 1 41  SER 41  33  41  SER SER A . n 
A 1 42  GLY 42  34  42  GLY GLY A . n 
A 1 43  TRP 43  35  43  TRP TRP A . n 
A 1 44  PRO 44  36  44  PRO PRO A . n 
A 1 45  THR 45  37  45  THR THR A . n 
A 1 46  ALA 46  38  46  ALA ALA A . n 
A 1 47  THR 47  39  47  THR THR A . n 
A 1 48  ASP 48  40  48  ASP ASP A . n 
A 1 49  LEU 49  41  49  LEU LEU A . n 
A 1 50  SER 50  42  50  SER SER A . n 
A 1 51  GLY 51  43  51  GLY GLY A . n 
A 1 52  GLY 52  44  52  GLY GLY A . n 
A 1 53  ALA 53  45  53  ALA ALA A . n 
A 1 54  GLN 54  46  54  GLN GLN A . n 
A 1 55  PRO 55  47  55  PRO PRO A . n 
A 1 56  ARG 56  48  56  ARG ARG A . n 
A 1 57  ARG 57  49  57  ARG ARG A . n 
A 1 58  PHE 58  50  58  PHE PHE A . n 
A 1 59  GLU 59  51  59  GLU GLU A . n 
A 1 60  GLY 60  52  60  GLY GLY A . n 
A 1 61  THR 61  53  61  THR THR A . n 
A 1 62  ILE 62  54  62  ILE ILE A . n 
A 1 63  PHE 63  55  63  PHE PHE A . n 
A 1 64  ASP 64  56  64  ASP ASP A . n 
A 1 65  VAL 65  57  65  VAL VAL A . n 
A 1 66  MET 66  58  66  MET MET A . n 
A 1 67  THR 67  59  67  THR THR A . n 
A 1 68  ARG 68  60  68  ARG ARG A . n 
A 1 69  GLY 69  61  69  GLY GLY A . n 
A 1 70  THR 70  62  70  THR THR A . n 
A 1 71  ILE 71  63  71  ILE ILE A . n 
A 1 72  PRO 72  64  72  PRO PRO A . n 
A 1 73  LYS 73  65  73  LYS LYS A . n 
A 1 74  GLU 74  66  74  GLU GLU A . n 
A 1 75  LEU 75  67  75  LEU LEU A . n 
A 1 76  HIS 76  68  76  HIS HIS A . n 
A 1 77  GLY 77  69  77  GLY GLY A . n 
A 1 78  THR 78  70  78  THR THR A . n 
A 1 79  PHE 79  71  79  PHE PHE A . n 
A 1 80  TYR 80  72  80  TYR TYR A . n 
A 1 81  ARG 81  73  81  ARG ARG A . n 
A 1 82  ILE 82  74  82  ILE ILE A . n 
A 1 83  MET 83  75  83  MET MET A . n 
A 1 84  PRO 84  76  84  PRO PRO A . n 
A 1 85  ASP 85  77  85  ASP ASP A . n 
A 1 86  TYR 86  78  86  TYR TYR A . n 
A 1 87  ALA 87  79  87  ALA ALA A . n 
A 1 88  GLN 88  80  88  GLN GLN A . n 
A 1 89  PRO 89  81  89  PRO PRO A . n 
A 1 90  PRO 90  82  90  PRO PRO A . n 
A 1 91  THR 91  83  91  THR THR A . n 
A 1 92  TYR 92  84  92  TYR TYR A . n 
A 1 93  TYR 93  85  93  TYR TYR A . n 
A 1 94  LYS 94  86  94  LYS LYS A . n 
A 1 95  GLY 95  87  95  GLY GLY A . n 
A 1 96  GLY 96  88  96  GLY GLY A . n 
A 1 97  GLU 97  89  97  GLU GLU A . n 
A 1 98  LEU 98  90  98  LEU LEU A . n 
A 1 99  ASN 99  91  99  ASN ASN A . n 
A 1 100 ALA 100 92  100 ALA ALA A . n 
A 1 101 PRO 101 93  101 PRO PRO A . n 
A 1 102 ILE 102 94  102 ILE ILE A . n 
A 1 103 ASP 103 95  103 ASP ASP A . n 
A 1 104 GLY 104 96  104 GLY GLY A . n 
A 1 105 ASP 105 97  105 ASP ASP A . n 
A 1 106 GLY 106 98  106 GLY GLY A . n 
A 1 107 THR 107 99  107 THR THR A . n 
A 1 108 VAL 108 100 108 VAL VAL A . n 
A 1 109 ALA 109 101 109 ALA ALA A . n 
A 1 110 ALA 110 102 110 ALA ALA A . n 
A 1 111 PHE 111 103 111 PHE PHE A . n 
A 1 112 ARG 112 104 112 ARG ARG A . n 
A 1 113 PHE 113 105 113 PHE PHE A . n 
A 1 114 LYS 114 106 114 LYS LYS A . n 
A 1 115 ASP 115 107 115 ASP ASP A . n 
A 1 116 GLY 116 108 116 GLY GLY A . n 
A 1 117 LYS 117 109 117 LYS LYS A . n 
A 1 118 VAL 118 110 118 VAL VAL A . n 
A 1 119 ASP 119 111 119 ASP ASP A . n 
A 1 120 TYR 120 112 120 TYR TYR A . n 
A 1 121 ARG 121 113 121 ARG ARG A . n 
A 1 122 GLN 122 114 122 GLN GLN A . n 
A 1 123 ARG 123 115 123 ARG ARG A . n 
A 1 124 PHE 124 116 124 PHE PHE A . n 
A 1 125 VAL 125 117 125 VAL VAL A . n 
A 1 126 GLU 126 118 126 GLU GLU A . n 
A 1 127 THR 127 119 127 THR THR A . n 
A 1 128 ASP 128 120 128 ASP ASP A . n 
A 1 129 ARG 129 121 129 ARG ARG A . n 
A 1 130 PHE 130 122 130 PHE PHE A . n 
A 1 131 LYS 131 123 131 LYS LYS A . n 
A 1 132 VAL 132 124 132 VAL VAL A . n 
A 1 133 GLU 133 125 133 GLU GLU A . n 
A 1 134 ARG 134 126 134 ARG ARG A . n 
A 1 135 ARG 135 127 135 ARG ARG A . n 
A 1 136 ALA 136 128 136 ALA ALA A . n 
A 1 137 ARG 137 129 137 ARG ARG A . n 
A 1 138 LYS 138 130 138 LYS LYS A . n 
A 1 139 SER 139 131 139 SER SER A . n 
A 1 140 MET 140 132 140 MET MET A . n 
A 1 141 TYR 141 133 141 TYR TYR A . n 
A 1 142 GLY 142 134 142 GLY GLY A . n 
A 1 143 LEU 143 135 143 LEU LEU A . n 
A 1 144 TYR 144 136 144 TYR TYR A . n 
A 1 145 ARG 145 137 145 ARG ARG A . n 
A 1 146 ASN 146 138 146 ASN ASN A . n 
A 1 147 PRO 147 139 147 PRO PRO A . n 
A 1 148 TYR 148 140 148 TYR TYR A . n 
A 1 149 THR 149 141 149 THR THR A . n 
A 1 150 HIS 150 142 150 HIS HIS A . n 
A 1 151 HIS 151 143 151 HIS HIS A . n 
A 1 152 PRO 152 144 152 PRO PRO A . n 
A 1 153 CYS 153 145 153 CYS CYS A . n 
A 1 154 VAL 154 146 154 VAL VAL A . n 
A 1 155 ARG 155 147 155 ARG ARG A . n 
A 1 156 GLN 156 148 156 GLN GLN A . n 
A 1 157 THR 157 149 157 THR THR A . n 
A 1 158 VAL 158 150 158 VAL VAL A . n 
A 1 159 GLU 159 151 159 GLU GLU A . n 
A 1 160 SER 160 152 160 SER SER A . n 
A 1 161 THR 161 153 161 THR THR A . n 
A 1 162 ALA 162 154 162 ALA ALA A . n 
A 1 163 ASN 163 155 163 ASN ASN A . n 
A 1 164 THR 164 156 164 THR THR A . n 
A 1 165 ASN 165 157 165 ASN ASN A . n 
A 1 166 VAL 166 158 166 VAL VAL A . n 
A 1 167 VAL 167 159 167 VAL VAL A . n 
A 1 168 MET 168 160 168 MET MET A . n 
A 1 169 HIS 169 161 169 HIS HIS A . n 
A 1 170 ALA 170 162 170 ALA ALA A . n 
A 1 171 GLY 171 163 171 GLY GLY A . n 
A 1 172 ARG 172 164 172 ARG ARG A . n 
A 1 173 PHE 173 165 173 PHE PHE A . n 
A 1 174 LEU 174 166 174 LEU LEU A . n 
A 1 175 ALA 175 167 175 ALA ALA A . n 
A 1 176 MET 176 168 176 MET MET A . n 
A 1 177 LYS 177 169 177 LYS LYS A . n 
A 1 178 GLU 178 170 178 GLU GLU A . n 
A 1 179 ASN 179 171 179 ASN ASN A . n 
A 1 180 GLY 180 172 180 GLY GLY A . n 
A 1 181 ASN 181 173 181 ASN ASN A . n 
A 1 182 ALA 182 174 182 ALA ALA A . n 
A 1 183 TYR 183 175 183 TYR TYR A . n 
A 1 184 GLU 184 176 184 GLU GLU A . n 
A 1 185 MET 185 177 185 MET MET A . n 
A 1 186 ASP 186 178 186 ASP ASP A . n 
A 1 187 PRO 187 179 187 PRO PRO A . n 
A 1 188 HIS 188 180 188 HIS HIS A . n 
A 1 189 THR 189 181 189 THR THR A . n 
A 1 190 LEU 190 182 190 LEU LEU A . n 
A 1 191 LYS 191 183 191 LYS LYS A . n 
A 1 192 THR 192 184 192 THR THR A . n 
A 1 193 LEU 193 185 193 LEU LEU A . n 
A 1 194 GLY 194 186 194 GLY GLY A . n 
A 1 195 TYR 195 187 195 TYR TYR A . n 
A 1 196 ASN 196 188 196 ASN ASN A . n 
A 1 197 PRO 197 189 197 PRO PRO A . n 
A 1 198 PHE 198 190 198 PHE PHE A . n 
A 1 199 ASN 199 191 199 ASN ASN A . n 
A 1 200 LEU 200 192 200 LEU LEU A . n 
A 1 201 PRO 201 193 201 PRO PRO A . n 
A 1 202 SER 202 194 202 SER SER A . n 
A 1 203 LYS 203 195 203 LYS LYS A . n 
A 1 204 THR 204 196 204 THR THR A . n 
A 1 205 MET 205 197 205 MET MET A . n 
A 1 206 THR 206 198 206 THR THR A . n 
A 1 207 ALA 207 199 207 ALA ALA A . n 
A 1 208 HIS 208 200 208 HIS HIS A . n 
A 1 209 PRO 209 201 209 PRO PRO A . n 
A 1 210 LYS 210 202 210 LYS LYS A . n 
A 1 211 GLN 211 203 211 GLN GLN A . n 
A 1 212 CYS 212 204 212 CYS CYS A . n 
A 1 213 SER 213 205 213 SER SER A . n 
A 1 214 VAL 214 206 214 VAL VAL A . n 
A 1 215 THR 215 207 215 THR THR A . n 
A 1 216 GLY 216 208 216 GLY GLY A . n 
A 1 217 ASN 217 209 217 ASN ASN A . n 
A 1 218 LEU 218 210 218 LEU LEU A . n 
A 1 219 VAL 219 211 219 VAL VAL A . n 
A 1 220 GLY 220 212 220 GLY GLY A . n 
A 1 221 PHE 221 213 221 PHE PHE A . n 
A 1 222 GLY 222 214 222 GLY GLY A . n 
A 1 223 TYR 223 215 223 TYR TYR A . n 
A 1 224 GLU 224 216 224 GLU GLU A . n 
A 1 225 ALA 225 217 225 ALA ALA A . n 
A 1 226 LYS 226 218 226 LYS LYS A . n 
A 1 227 GLY 227 219 227 GLY GLY A . n 
A 1 228 LEU 228 220 228 LEU LEU A . n 
A 1 229 ALA 229 221 229 ALA ALA A . n 
A 1 230 THR 230 222 230 THR THR A . n 
A 1 231 LYS 231 223 231 LYS LYS A . n 
A 1 232 ASP 232 224 232 ASP ASP A . n 
A 1 233 VAL 233 225 233 VAL VAL A . n 
A 1 234 TYR 234 226 234 TYR TYR A . n 
A 1 235 TYR 235 227 235 TYR TYR A . n 
A 1 236 PHE 236 228 236 PHE PHE A . n 
A 1 237 GLU 237 229 237 GLU GLU A . n 
A 1 238 VAL 238 230 238 VAL VAL A . n 
A 1 239 ASP 239 231 239 ASP ASP A . n 
A 1 240 PRO 240 232 240 PRO PRO A . n 
A 1 241 SER 241 233 241 SER SER A . n 
A 1 242 GLY 242 234 242 GLY GLY A . n 
A 1 243 LYS 243 235 243 LYS LYS A . n 
A 1 244 VAL 244 236 244 VAL VAL A . n 
A 1 245 VAL 245 237 245 VAL VAL A . n 
A 1 246 ARG 246 238 246 ARG ARG A . n 
A 1 247 ASP 247 239 247 ASP ASP A . n 
A 1 248 LEU 248 240 248 LEU LEU A . n 
A 1 249 TRP 249 241 249 TRP TRP A . n 
A 1 250 LEU 250 242 250 LEU LEU A . n 
A 1 251 GLU 251 243 251 GLU GLU A . n 
A 1 252 ALA 252 244 252 ALA ALA A . n 
A 1 253 PRO 253 245 253 PRO PRO A . n 
A 1 254 TRP 254 246 254 TRP TRP A . n 
A 1 255 CYS 255 247 255 CYS CYS A . n 
A 1 256 ALA 256 248 256 ALA ALA A . n 
A 1 257 PHE 257 249 257 PHE PHE A . n 
A 1 258 ILE 258 250 258 ILE ILE A . n 
A 1 259 HIS 259 251 259 HIS HIS A . n 
A 1 260 ASP 260 252 260 ASP ASP A . n 
A 1 261 CYS 261 253 261 CYS CYS A . n 
A 1 262 ALA 262 254 262 ALA ALA A . n 
A 1 263 LEU 263 255 263 LEU LEU A . n 
A 1 264 THR 264 256 264 THR THR A . n 
A 1 265 PRO 265 257 265 PRO PRO A . n 
A 1 266 ASN 266 258 266 ASN ASN A . n 
A 1 267 TYR 267 259 267 TYR TYR A . n 
A 1 268 LEU 268 260 268 LEU LEU A . n 
A 1 269 VAL 269 261 269 VAL VAL A . n 
A 1 270 LEU 270 262 270 LEU LEU A . n 
A 1 271 MET 271 263 271 MET MET A . n 
A 1 272 LEU 272 264 272 LEU LEU A . n 
A 1 273 TRP 273 265 273 TRP TRP A . n 
A 1 274 PRO 274 266 274 PRO PRO A . n 
A 1 275 PHE 275 267 275 PHE PHE A . n 
A 1 276 GLU 276 268 276 GLU GLU A . n 
A 1 277 ALA 277 269 277 ALA ALA A . n 
A 1 278 ASN 278 270 278 ASN ASN A . n 
A 1 279 LEU 279 271 279 LEU LEU A . n 
A 1 280 GLU 280 272 280 GLU GLU A . n 
A 1 281 ARG 281 273 281 ARG ARG A . n 
A 1 282 MET 282 274 282 MET MET A . n 
A 1 283 LYS 283 275 283 LYS LYS A . n 
A 1 284 ALA 284 276 284 ALA ALA A . n 
A 1 285 GLY 285 277 285 GLY GLY A . n 
A 1 286 GLY 286 278 286 GLY GLY A . n 
A 1 287 HIS 287 279 287 HIS HIS A . n 
A 1 288 HIS 288 280 288 HIS HIS A . n 
A 1 289 TRP 289 281 289 TRP TRP A . n 
A 1 290 ALA 290 282 290 ALA ALA A . n 
A 1 291 TYR 291 283 291 TYR TYR A . n 
A 1 292 ASP 292 284 292 ASP ASP A . n 
A 1 293 TYR 293 285 293 TYR TYR A . n 
A 1 294 THR 294 286 294 THR THR A . n 
A 1 295 LYS 295 287 295 LYS LYS A . n 
A 1 296 PRO 296 288 296 PRO PRO A . n 
A 1 297 ILE 297 289 297 ILE ILE A . n 
A 1 298 THR 298 290 298 THR THR A . n 
A 1 299 TRP 299 291 299 TRP TRP A . n 
A 1 300 ILE 300 292 300 ILE ILE A . n 
A 1 301 THR 301 293 301 THR THR A . n 
A 1 302 ILE 302 294 302 ILE ILE A . n 
A 1 303 PRO 303 295 303 PRO PRO A . n 
A 1 304 ARG 304 296 304 ARG ARG A . n 
A 1 305 GLY 305 297 305 GLY GLY A . n 
A 1 306 ALA 306 298 306 ALA ALA A . n 
A 1 307 LYS 307 299 307 LYS LYS A . n 
A 1 308 SER 308 300 308 SER SER A . n 
A 1 309 LYS 309 301 309 LYS LYS A . n 
A 1 310 ASP 310 302 310 ASP ASP A . n 
A 1 311 GLU 311 303 311 GLU GLU A . n 
A 1 312 VAL 312 304 312 VAL VAL A . n 
A 1 313 LYS 313 305 313 LYS LYS A . n 
A 1 314 TYR 314 306 314 TYR TYR A . n 
A 1 315 TRP 315 307 315 TRP TRP A . n 
A 1 316 HIS 316 308 316 HIS HIS A . n 
A 1 317 TRP 317 309 317 TRP TRP A . n 
A 1 318 LYS 318 310 318 LYS LYS A . n 
A 1 319 ASN 319 311 319 ASN ASN A . n 
A 1 320 GLY 320 312 320 GLY GLY A . n 
A 1 321 MET 321 313 321 MET MET A . n 
A 1 322 PRO 322 314 322 PRO PRO A . n 
A 1 323 ILE 323 315 323 ILE ILE A . n 
A 1 324 HIS 324 316 324 HIS HIS A . n 
A 1 325 THR 325 317 325 THR THR A . n 
A 1 326 ALA 326 318 326 ALA ALA A . n 
A 1 327 SER 327 319 327 SER SER A . n 
A 1 328 GLY 328 320 328 GLY GLY A . n 
A 1 329 PHE 329 321 329 PHE PHE A . n 
A 1 330 GLU 330 322 330 GLU GLU A . n 
A 1 331 ASP 331 323 331 ASP ASP A . n 
A 1 332 GLU 332 324 332 GLU GLU A . n 
A 1 333 GLN 333 325 333 GLN GLN A . n 
A 1 334 GLY 334 326 334 GLY GLY A . n 
A 1 335 ARG 335 327 335 ARG ARG A . n 
A 1 336 ILE 336 328 336 ILE ILE A . n 
A 1 337 ILE 337 329 337 ILE ILE A . n 
A 1 338 ILE 338 330 338 ILE ILE A . n 
A 1 339 ASP 339 331 339 ASP ASP A . n 
A 1 340 SER 340 332 340 SER SER A . n 
A 1 341 SER 341 333 341 SER SER A . n 
A 1 342 LEU 342 334 342 LEU LEU A . n 
A 1 343 VAL 343 335 343 VAL VAL A . n 
A 1 344 HIS 344 336 344 HIS HIS A . n 
A 1 345 GLY 345 337 345 GLY GLY A . n 
A 1 346 ASN 346 338 346 ASN ASN A . n 
A 1 347 ALA 347 339 347 ALA ALA A . n 
A 1 348 PHE 348 340 348 PHE PHE A . n 
A 1 349 PRO 349 341 349 PRO PRO A . n 
A 1 350 PHE 350 342 350 PHE PHE A . n 
A 1 351 PHE 351 343 351 PHE PHE A . n 
A 1 352 PRO 352 344 352 PRO PRO A . n 
A 1 353 PRO 353 345 353 PRO PRO A . n 
A 1 354 ASP 354 346 354 ASP ASP A . n 
A 1 355 SER 355 347 355 SER SER A . n 
A 1 356 ASP 356 348 356 ASP ASP A . n 
A 1 357 GLU 357 349 357 GLU GLU A . n 
A 1 358 GLN 358 350 358 GLN GLN A . n 
A 1 359 LYS 359 351 359 LYS LYS A . n 
A 1 360 LYS 360 352 360 LYS LYS A . n 
A 1 361 LYS 361 353 361 LYS LYS A . n 
A 1 362 GLN 362 354 362 GLN GLN A . n 
A 1 363 GLU 363 355 363 GLU GLU A . n 
A 1 364 ALA 364 356 364 ALA ALA A . n 
A 1 365 ASP 365 357 365 ASP ASP A . n 
A 1 366 GLY 366 358 366 GLY GLY A . n 
A 1 367 THR 367 359 367 THR THR A . n 
A 1 368 PRO 368 360 368 PRO PRO A . n 
A 1 369 LYS 369 361 369 LYS LYS A . n 
A 1 370 ALA 370 362 370 ALA ALA A . n 
A 1 371 GLN 371 363 371 GLN GLN A . n 
A 1 372 PHE 372 364 372 PHE PHE A . n 
A 1 373 VAL 373 365 373 VAL VAL A . n 
A 1 374 ARG 374 366 374 ARG ARG A . n 
A 1 375 TRP 375 367 375 TRP TRP A . n 
A 1 376 THR 376 368 376 THR THR A . n 
A 1 377 ILE 377 369 377 ILE ILE A . n 
A 1 378 ASP 378 370 378 ASP ASP A . n 
A 1 379 PRO 379 371 379 PRO PRO A . n 
A 1 380 ARG 380 372 380 ARG ARG A . n 
A 1 381 LYS 381 373 381 LYS LYS A . n 
A 1 382 ASP 382 374 382 ASP ASP A . n 
A 1 383 ASN 383 375 383 ASN ASN A . n 
A 1 384 ASN 384 376 384 ASN ASN A . n 
A 1 385 GLU 385 377 385 GLU GLU A . n 
A 1 386 GLN 386 378 386 GLN GLN A . n 
A 1 387 LEU 387 379 387 LEU LEU A . n 
A 1 388 PRO 388 380 388 PRO PRO A . n 
A 1 389 ASP 389 381 389 ASP ASP A . n 
A 1 390 PRO 390 382 390 PRO PRO A . n 
A 1 391 GLU 391 383 391 GLU GLU A . n 
A 1 392 VAL 392 384 392 VAL VAL A . n 
A 1 393 ILE 393 385 393 ILE ILE A . n 
A 1 394 LEU 394 386 394 LEU LEU A . n 
A 1 395 ASP 395 387 395 ASP ASP A . n 
A 1 396 THR 396 388 396 THR THR A . n 
A 1 397 PRO 397 389 397 PRO PRO A . n 
A 1 398 SER 398 390 398 SER SER A . n 
A 1 399 GLU 399 391 399 GLU GLU A . n 
A 1 400 PHE 400 392 400 PHE PHE A . n 
A 1 401 PRO 401 393 401 PRO PRO A . n 
A 1 402 GLN 402 394 402 GLN GLN A . n 
A 1 403 ILE 403 395 403 ILE ILE A . n 
A 1 404 ASP 404 396 404 ASP ASP A . n 
A 1 405 ASN 405 397 405 ASN ASN A . n 
A 1 406 ARG 406 398 406 ARG ARG A . n 
A 1 407 PHE 407 399 407 PHE PHE A . n 
A 1 408 MET 408 400 408 MET MET A . n 
A 1 409 GLY 409 401 409 GLY GLY A . n 
A 1 410 VAL 410 402 410 VAL VAL A . n 
A 1 411 GLU 411 403 411 GLU GLU A . n 
A 1 412 TYR 412 404 412 TYR TYR A . n 
A 1 413 SER 413 405 413 SER SER A . n 
A 1 414 SER 414 406 414 SER SER A . n 
A 1 415 ALA 415 407 415 ALA ALA A . n 
A 1 416 PHE 416 408 416 PHE PHE A . n 
A 1 417 ILE 417 409 417 ILE ILE A . n 
A 1 418 ASN 418 410 418 ASN ASN A . n 
A 1 419 VAL 419 411 419 VAL VAL A . n 
A 1 420 PHE 420 412 420 PHE PHE A . n 
A 1 421 VAL 421 413 421 VAL VAL A . n 
A 1 422 PRO 422 414 422 PRO PRO A . n 
A 1 423 ASP 423 415 423 ASP ASP A . n 
A 1 424 ARG 424 416 424 ARG ARG A . n 
A 1 425 SER 425 417 425 SER SER A . n 
A 1 426 ASP 426 418 426 ASP ASP A . n 
A 1 427 GLY 427 419 427 GLY GLY A . n 
A 1 428 ASN 428 420 428 ASN ASN A . n 
A 1 429 LYS 429 421 429 LYS LYS A . n 
A 1 430 ASN 430 422 430 ASN ASN A . n 
A 1 431 VAL 431 423 431 VAL VAL A . n 
A 1 432 PHE 432 424 432 PHE PHE A . n 
A 1 433 GLN 433 425 433 GLN GLN A . n 
A 1 434 GLY 434 426 434 GLY GLY A . n 
A 1 435 LEU 435 427 435 LEU LEU A . n 
A 1 436 ASN 436 428 436 ASN ASN A . n 
A 1 437 GLY 437 429 437 GLY GLY A . n 
A 1 438 LEU 438 430 438 LEU LEU A . n 
A 1 439 ALA 439 431 439 ALA ALA A . n 
A 1 440 HIS 440 432 440 HIS HIS A . n 
A 1 441 TYR 441 433 441 TYR TYR A . n 
A 1 442 LYS 442 434 442 LYS LYS A . n 
A 1 443 ARG 443 435 443 ARG ARG A . n 
A 1 444 LYS 444 436 444 LYS LYS A . n 
A 1 445 GLU 445 437 445 GLU GLU A . n 
A 1 446 GLY 446 438 446 GLY GLY A . n 
A 1 447 THR 447 439 447 THR THR A . n 
A 1 448 THR 448 440 448 THR THR A . n 
A 1 449 GLU 449 441 449 GLU GLU A . n 
A 1 450 TRP 450 442 450 TRP TRP A . n 
A 1 451 TYR 451 443 451 TYR TYR A . n 
A 1 452 TYR 452 444 452 TYR TYR A . n 
A 1 453 ALA 453 445 453 ALA ALA A . n 
A 1 454 GLY 454 446 454 GLY GLY A . n 
A 1 455 ASP 455 447 455 ASP ASP A . n 
A 1 456 ASN 456 448 456 ASN ASN A . n 
A 1 457 CYS 457 449 457 CYS CYS A . n 
A 1 458 LEU 458 450 458 LEU LEU A . n 
A 1 459 ILE 459 451 459 ILE ILE A . n 
A 1 460 GLN 460 452 460 GLN GLN A . n 
A 1 461 GLU 461 453 461 GLU GLU A . n 
A 1 462 PRO 462 454 462 PRO PRO A . n 
A 1 463 VAL 463 455 463 VAL VAL A . n 
A 1 464 PHE 464 456 464 PHE PHE A . n 
A 1 465 SER 465 457 465 SER SER A . n 
A 1 466 PRO 466 458 466 PRO PRO A . n 
A 1 467 ARG 467 459 467 ARG ARG A . n 
A 1 468 SER 468 460 468 SER SER A . n 
A 1 469 LYS 469 461 469 LYS LYS A . n 
A 1 470 ASP 470 462 470 ASP ASP A . n 
A 1 471 ALA 471 463 471 ALA ALA A . n 
A 1 472 PRO 472 464 472 PRO PRO A . n 
A 1 473 GLU 473 465 473 GLU GLU A . n 
A 1 474 GLY 474 466 474 GLY GLY A . n 
A 1 475 ASP 475 467 475 ASP ASP A . n 
A 1 476 GLY 476 468 476 GLY GLY A . n 
A 1 477 PHE 477 469 477 PHE PHE A . n 
A 1 478 VAL 478 470 478 VAL VAL A . n 
A 1 479 LEU 479 471 479 LEU LEU A . n 
A 1 480 ALA 480 472 480 ALA ALA A . n 
A 1 481 ILE 481 473 481 ILE ILE A . n 
A 1 482 VAL 482 474 482 VAL VAL A . n 
A 1 483 ASP 483 475 483 ASP ASP A . n 
A 1 484 ARG 484 476 484 ARG ARG A . n 
A 1 485 LEU 485 477 485 LEU LEU A . n 
A 1 486 ASP 486 478 486 ASP ASP A . n 
A 1 487 LEU 487 479 487 LEU LEU A . n 
A 1 488 ASN 488 480 488 ASN ASN A . n 
A 1 489 ARG 489 481 489 ARG ARG A . n 
A 1 490 SER 490 482 490 SER SER A . n 
A 1 491 GLU 491 483 491 GLU GLU A . n 
A 1 492 VAL 492 484 492 VAL VAL A . n 
A 1 493 VAL 493 485 493 VAL VAL A . n 
A 1 494 VAL 494 486 494 VAL VAL A . n 
A 1 495 ILE 495 487 495 ILE ILE A . n 
A 1 496 ASP 496 488 496 ASP ASP A . n 
A 1 497 THR 497 489 497 THR THR A . n 
A 1 498 ARG 498 490 498 ARG ARG A . n 
A 1 499 ASP 499 491 499 ASP ASP A . n 
A 1 500 PHE 500 492 500 PHE PHE A . n 
A 1 501 THR 501 493 501 THR THR A . n 
A 1 502 LYS 502 494 502 LYS LYS A . n 
A 1 503 ALA 503 495 503 ALA ALA A . n 
A 1 504 VAL 504 496 504 VAL VAL A . n 
A 1 505 ALA 505 497 505 ALA ALA A . n 
A 1 506 ALA 506 498 506 ALA ALA A . n 
A 1 507 VAL 507 499 507 VAL VAL A . n 
A 1 508 GLN 508 500 508 GLN GLN A . n 
A 1 509 LEU 509 501 509 LEU LEU A . n 
A 1 510 PRO 510 502 510 PRO PRO A . n 
A 1 511 PHE 511 503 511 PHE PHE A . n 
A 1 512 ALA 512 504 512 ALA ALA A . n 
A 1 513 ILE 513 505 513 ILE ILE A . n 
A 1 514 ARG 514 506 514 ARG ARG A . n 
A 1 515 SER 515 507 515 SER SER A . n 
A 1 516 GLY 516 508 516 GLY GLY A . n 
A 1 517 ILE 517 509 517 ILE ILE A . n 
A 1 518 HIS 518 510 518 HIS HIS A . n 
A 1 519 GLY 519 511 519 GLY GLY A . n 
A 1 520 GLN 520 512 520 GLN GLN A . n 
A 1 521 TRP 521 513 521 TRP TRP A . n 
A 1 522 ILE 522 514 522 ILE ILE A . n 
A 1 523 PRO 523 515 523 PRO PRO A . n 
A 1 524 GLY 524 516 524 GLY GLY A . n 
A 1 525 GLU 525 517 525 GLU GLU A . n 
A 1 526 VAL 526 518 526 VAL VAL A . n 
A 1 527 THR 527 519 527 THR THR A . n 
A 1 528 PRO 528 520 528 PRO PRO A . n 
A 1 529 ASP 529 521 529 ASP ASP A . n 
A 1 530 PHE 530 522 530 PHE PHE A . n 
A 1 531 GLU 531 523 531 GLU GLU A . n 
A 1 532 THR 532 524 532 THR THR A . n 
A 1 533 LYS 533 525 533 LYS LYS A . n 
A 1 534 GLY 534 526 534 GLY GLY A . n 
A 1 535 LEU 535 527 535 LEU LEU A . n 
A 1 536 VAL 536 528 536 VAL VAL A . n 
A 1 537 ASP 537 529 537 ASP ASP A . n 
A 1 538 LEU 538 530 538 LEU LEU A . n 
A 1 539 PRO 539 531 539 PRO PRO A . n 
A 1 540 LYS 540 532 540 LYS LYS A . n 
A 1 541 GLU 541 533 541 GLU GLU A . n 
A 1 542 GLU 542 534 542 GLU GLU A . n 
A 1 543 HIS 543 535 543 HIS HIS A . n 
A 1 544 TRP 544 536 544 TRP TRP A . n 
A 1 545 ALA 545 537 545 ALA ALA A . n 
A 1 546 PRO 546 538 546 PRO PRO A . n 
A 1 547 LEU 547 539 547 LEU LEU A . n 
A 1 548 SER 548 540 548 SER SER A . n 
A 1 549 GLN 549 541 549 GLN GLN A . n 
A 1 550 SER 550 542 550 SER SER A . n 
A 1 551 PRO 551 543 551 PRO PRO A . n 
A 1 552 TYR 552 544 552 TYR TYR A . n 
A 1 553 ASP 553 545 553 ASP ASP A . n 
A 1 554 PRO 554 546 554 PRO PRO A . n 
A 1 555 ASP 555 547 555 ASP ASP A . n 
A 1 556 ALA 556 548 556 ALA ALA A . n 
B 1 1   MET 1   -7  ?   ?   ?   B . n 
B 1 2   TRP 2   -6  ?   ?   ?   B . n 
B 1 3   SER 3   -5  ?   ?   ?   B . n 
B 1 4   HIS 4   -4  ?   ?   ?   B . n 
B 1 5   PRO 5   -3  ?   ?   ?   B . n 
B 1 6   GLN 6   -2  ?   ?   ?   B . n 
B 1 7   PHE 7   -1  ?   ?   ?   B . n 
B 1 8   GLU 8   0   ?   ?   ?   B . n 
B 1 9   LYS 9   1   ?   ?   ?   B . n 
B 1 10  ALA 10  2   ?   ?   ?   B . n 
B 1 11  PRO 11  3   ?   ?   ?   B . n 
B 1 12  THR 12  4   ?   ?   ?   B . n 
B 1 13  ALA 13  5   ?   ?   ?   B . n 
B 1 14  THR 14  6   ?   ?   ?   B . n 
B 1 15  GLN 15  7   ?   ?   ?   B . n 
B 1 16  GLU 16  8   ?   ?   ?   B . n 
B 1 17  PRO 17  9   ?   ?   ?   B . n 
B 1 18  VAL 18  10  ?   ?   ?   B . n 
B 1 19  PRO 19  11  ?   ?   ?   B . n 
B 1 20  VAL 20  12  ?   ?   ?   B . n 
B 1 21  PRO 21  13  ?   ?   ?   B . n 
B 1 22  VAL 22  14  ?   ?   ?   B . n 
B 1 23  THR 23  15  ?   ?   ?   B . n 
B 1 24  SER 24  16  ?   ?   ?   B . n 
B 1 25  LYS 25  17  ?   ?   ?   B . n 
B 1 26  ALA 26  18  ?   ?   ?   B . n 
B 1 27  ALA 27  19  ?   ?   ?   B . n 
B 1 28  PRO 28  20  ?   ?   ?   B . n 
B 1 29  SER 29  21  ?   ?   ?   B . n 
B 1 30  HIS 30  22  ?   ?   ?   B . n 
B 1 31  GLY 31  23  ?   ?   ?   B . n 
B 1 32  TYR 32  24  32  TYR TYR B . n 
B 1 33  VAL 33  25  33  VAL VAL B . n 
B 1 34  HIS 34  26  34  HIS HIS B . n 
B 1 35  PRO 35  27  35  PRO PRO B . n 
B 1 36  THR 36  28  36  THR THR B . n 
B 1 37  ASP 37  29  37  ASP ASP B . n 
B 1 38  ILE 38  30  38  ILE ILE B . n 
B 1 39  LEU 39  31  39  LEU LEU B . n 
B 1 40  PRO 40  32  40  PRO PRO B . n 
B 1 41  SER 41  33  41  SER SER B . n 
B 1 42  GLY 42  34  42  GLY GLY B . n 
B 1 43  TRP 43  35  43  TRP TRP B . n 
B 1 44  PRO 44  36  44  PRO PRO B . n 
B 1 45  THR 45  37  45  THR THR B . n 
B 1 46  ALA 46  38  46  ALA ALA B . n 
B 1 47  THR 47  39  47  THR THR B . n 
B 1 48  ASP 48  40  48  ASP ASP B . n 
B 1 49  LEU 49  41  49  LEU LEU B . n 
B 1 50  SER 50  42  50  SER SER B . n 
B 1 51  GLY 51  43  51  GLY GLY B . n 
B 1 52  GLY 52  44  52  GLY GLY B . n 
B 1 53  ALA 53  45  53  ALA ALA B . n 
B 1 54  GLN 54  46  54  GLN GLN B . n 
B 1 55  PRO 55  47  55  PRO PRO B . n 
B 1 56  ARG 56  48  56  ARG ARG B . n 
B 1 57  ARG 57  49  57  ARG ARG B . n 
B 1 58  PHE 58  50  58  PHE PHE B . n 
B 1 59  GLU 59  51  59  GLU GLU B . n 
B 1 60  GLY 60  52  60  GLY GLY B . n 
B 1 61  THR 61  53  61  THR THR B . n 
B 1 62  ILE 62  54  62  ILE ILE B . n 
B 1 63  PHE 63  55  63  PHE PHE B . n 
B 1 64  ASP 64  56  64  ASP ASP B . n 
B 1 65  VAL 65  57  65  VAL VAL B . n 
B 1 66  MET 66  58  66  MET MET B . n 
B 1 67  THR 67  59  67  THR THR B . n 
B 1 68  ARG 68  60  68  ARG ARG B . n 
B 1 69  GLY 69  61  69  GLY GLY B . n 
B 1 70  THR 70  62  70  THR THR B . n 
B 1 71  ILE 71  63  71  ILE ILE B . n 
B 1 72  PRO 72  64  72  PRO PRO B . n 
B 1 73  LYS 73  65  73  LYS LYS B . n 
B 1 74  GLU 74  66  74  GLU GLU B . n 
B 1 75  LEU 75  67  75  LEU LEU B . n 
B 1 76  HIS 76  68  76  HIS HIS B . n 
B 1 77  GLY 77  69  77  GLY GLY B . n 
B 1 78  THR 78  70  78  THR THR B . n 
B 1 79  PHE 79  71  79  PHE PHE B . n 
B 1 80  TYR 80  72  80  TYR TYR B . n 
B 1 81  ARG 81  73  81  ARG ARG B . n 
B 1 82  ILE 82  74  82  ILE ILE B . n 
B 1 83  MET 83  75  83  MET MET B . n 
B 1 84  PRO 84  76  84  PRO PRO B . n 
B 1 85  ASP 85  77  85  ASP ASP B . n 
B 1 86  TYR 86  78  86  TYR TYR B . n 
B 1 87  ALA 87  79  87  ALA ALA B . n 
B 1 88  GLN 88  80  88  GLN GLN B . n 
B 1 89  PRO 89  81  89  PRO PRO B . n 
B 1 90  PRO 90  82  90  PRO PRO B . n 
B 1 91  THR 91  83  91  THR THR B . n 
B 1 92  TYR 92  84  92  TYR TYR B . n 
B 1 93  TYR 93  85  93  TYR TYR B . n 
B 1 94  LYS 94  86  94  LYS LYS B . n 
B 1 95  GLY 95  87  95  GLY GLY B . n 
B 1 96  GLY 96  88  96  GLY GLY B . n 
B 1 97  GLU 97  89  97  GLU GLU B . n 
B 1 98  LEU 98  90  98  LEU LEU B . n 
B 1 99  ASN 99  91  99  ASN ASN B . n 
B 1 100 ALA 100 92  100 ALA ALA B . n 
B 1 101 PRO 101 93  101 PRO PRO B . n 
B 1 102 ILE 102 94  102 ILE ILE B . n 
B 1 103 ASP 103 95  103 ASP ASP B . n 
B 1 104 GLY 104 96  104 GLY GLY B . n 
B 1 105 ASP 105 97  105 ASP ASP B . n 
B 1 106 GLY 106 98  106 GLY GLY B . n 
B 1 107 THR 107 99  107 THR THR B . n 
B 1 108 VAL 108 100 108 VAL VAL B . n 
B 1 109 ALA 109 101 109 ALA ALA B . n 
B 1 110 ALA 110 102 110 ALA ALA B . n 
B 1 111 PHE 111 103 111 PHE PHE B . n 
B 1 112 ARG 112 104 112 ARG ARG B . n 
B 1 113 PHE 113 105 113 PHE PHE B . n 
B 1 114 LYS 114 106 114 LYS LYS B . n 
B 1 115 ASP 115 107 115 ASP ASP B . n 
B 1 116 GLY 116 108 116 GLY GLY B . n 
B 1 117 LYS 117 109 117 LYS LYS B . n 
B 1 118 VAL 118 110 118 VAL VAL B . n 
B 1 119 ASP 119 111 119 ASP ASP B . n 
B 1 120 TYR 120 112 120 TYR TYR B . n 
B 1 121 ARG 121 113 121 ARG ARG B . n 
B 1 122 GLN 122 114 122 GLN GLN B . n 
B 1 123 ARG 123 115 123 ARG ARG B . n 
B 1 124 PHE 124 116 124 PHE PHE B . n 
B 1 125 VAL 125 117 125 VAL VAL B . n 
B 1 126 GLU 126 118 126 GLU GLU B . n 
B 1 127 THR 127 119 127 THR THR B . n 
B 1 128 ASP 128 120 128 ASP ASP B . n 
B 1 129 ARG 129 121 129 ARG ARG B . n 
B 1 130 PHE 130 122 130 PHE PHE B . n 
B 1 131 LYS 131 123 131 LYS LYS B . n 
B 1 132 VAL 132 124 132 VAL VAL B . n 
B 1 133 GLU 133 125 133 GLU GLU B . n 
B 1 134 ARG 134 126 134 ARG ARG B . n 
B 1 135 ARG 135 127 135 ARG ARG B . n 
B 1 136 ALA 136 128 136 ALA ALA B . n 
B 1 137 ARG 137 129 137 ARG ARG B . n 
B 1 138 LYS 138 130 138 LYS LYS B . n 
B 1 139 SER 139 131 139 SER SER B . n 
B 1 140 MET 140 132 140 MET MET B . n 
B 1 141 TYR 141 133 141 TYR TYR B . n 
B 1 142 GLY 142 134 142 GLY GLY B . n 
B 1 143 LEU 143 135 143 LEU LEU B . n 
B 1 144 TYR 144 136 144 TYR TYR B . n 
B 1 145 ARG 145 137 145 ARG ARG B . n 
B 1 146 ASN 146 138 146 ASN ASN B . n 
B 1 147 PRO 147 139 147 PRO PRO B . n 
B 1 148 TYR 148 140 148 TYR TYR B . n 
B 1 149 THR 149 141 149 THR THR B . n 
B 1 150 HIS 150 142 150 HIS HIS B . n 
B 1 151 HIS 151 143 151 HIS HIS B . n 
B 1 152 PRO 152 144 152 PRO PRO B . n 
B 1 153 CYS 153 145 153 CYS CYS B . n 
B 1 154 VAL 154 146 154 VAL VAL B . n 
B 1 155 ARG 155 147 155 ARG ARG B . n 
B 1 156 GLN 156 148 156 GLN GLN B . n 
B 1 157 THR 157 149 157 THR THR B . n 
B 1 158 VAL 158 150 158 VAL VAL B . n 
B 1 159 GLU 159 151 159 GLU GLU B . n 
B 1 160 SER 160 152 160 SER SER B . n 
B 1 161 THR 161 153 161 THR THR B . n 
B 1 162 ALA 162 154 162 ALA ALA B . n 
B 1 163 ASN 163 155 163 ASN ASN B . n 
B 1 164 THR 164 156 164 THR THR B . n 
B 1 165 ASN 165 157 165 ASN ASN B . n 
B 1 166 VAL 166 158 166 VAL VAL B . n 
B 1 167 VAL 167 159 167 VAL VAL B . n 
B 1 168 MET 168 160 168 MET MET B . n 
B 1 169 HIS 169 161 169 HIS HIS B . n 
B 1 170 ALA 170 162 170 ALA ALA B . n 
B 1 171 GLY 171 163 171 GLY GLY B . n 
B 1 172 ARG 172 164 172 ARG ARG B . n 
B 1 173 PHE 173 165 173 PHE PHE B . n 
B 1 174 LEU 174 166 174 LEU LEU B . n 
B 1 175 ALA 175 167 175 ALA ALA B . n 
B 1 176 MET 176 168 176 MET MET B . n 
B 1 177 LYS 177 169 177 LYS LYS B . n 
B 1 178 GLU 178 170 178 GLU GLU B . n 
B 1 179 ASN 179 171 179 ASN ASN B . n 
B 1 180 GLY 180 172 180 GLY GLY B . n 
B 1 181 ASN 181 173 181 ASN ASN B . n 
B 1 182 ALA 182 174 182 ALA ALA B . n 
B 1 183 TYR 183 175 183 TYR TYR B . n 
B 1 184 GLU 184 176 184 GLU GLU B . n 
B 1 185 MET 185 177 185 MET MET B . n 
B 1 186 ASP 186 178 186 ASP ASP B . n 
B 1 187 PRO 187 179 187 PRO PRO B . n 
B 1 188 HIS 188 180 188 HIS HIS B . n 
B 1 189 THR 189 181 189 THR THR B . n 
B 1 190 LEU 190 182 190 LEU LEU B . n 
B 1 191 LYS 191 183 191 LYS LYS B . n 
B 1 192 THR 192 184 192 THR THR B . n 
B 1 193 LEU 193 185 193 LEU LEU B . n 
B 1 194 GLY 194 186 194 GLY GLY B . n 
B 1 195 TYR 195 187 195 TYR TYR B . n 
B 1 196 ASN 196 188 196 ASN ASN B . n 
B 1 197 PRO 197 189 197 PRO PRO B . n 
B 1 198 PHE 198 190 198 PHE PHE B . n 
B 1 199 ASN 199 191 199 ASN ASN B . n 
B 1 200 LEU 200 192 200 LEU LEU B . n 
B 1 201 PRO 201 193 201 PRO PRO B . n 
B 1 202 SER 202 194 202 SER SER B . n 
B 1 203 LYS 203 195 203 LYS LYS B . n 
B 1 204 THR 204 196 204 THR THR B . n 
B 1 205 MET 205 197 205 MET MET B . n 
B 1 206 THR 206 198 206 THR THR B . n 
B 1 207 ALA 207 199 207 ALA ALA B . n 
B 1 208 HIS 208 200 208 HIS HIS B . n 
B 1 209 PRO 209 201 209 PRO PRO B . n 
B 1 210 LYS 210 202 210 LYS LYS B . n 
B 1 211 GLN 211 203 211 GLN GLN B . n 
B 1 212 CYS 212 204 212 CYS CYS B . n 
B 1 213 SER 213 205 213 SER SER B . n 
B 1 214 VAL 214 206 214 VAL VAL B . n 
B 1 215 THR 215 207 215 THR THR B . n 
B 1 216 GLY 216 208 216 GLY GLY B . n 
B 1 217 ASN 217 209 217 ASN ASN B . n 
B 1 218 LEU 218 210 218 LEU LEU B . n 
B 1 219 VAL 219 211 219 VAL VAL B . n 
B 1 220 GLY 220 212 220 GLY GLY B . n 
B 1 221 PHE 221 213 221 PHE PHE B . n 
B 1 222 GLY 222 214 222 GLY GLY B . n 
B 1 223 TYR 223 215 223 TYR TYR B . n 
B 1 224 GLU 224 216 224 GLU GLU B . n 
B 1 225 ALA 225 217 225 ALA ALA B . n 
B 1 226 LYS 226 218 226 LYS LYS B . n 
B 1 227 GLY 227 219 227 GLY GLY B . n 
B 1 228 LEU 228 220 228 LEU LEU B . n 
B 1 229 ALA 229 221 229 ALA ALA B . n 
B 1 230 THR 230 222 230 THR THR B . n 
B 1 231 LYS 231 223 231 LYS LYS B . n 
B 1 232 ASP 232 224 232 ASP ASP B . n 
B 1 233 VAL 233 225 233 VAL VAL B . n 
B 1 234 TYR 234 226 234 TYR TYR B . n 
B 1 235 TYR 235 227 235 TYR TYR B . n 
B 1 236 PHE 236 228 236 PHE PHE B . n 
B 1 237 GLU 237 229 237 GLU GLU B . n 
B 1 238 VAL 238 230 238 VAL VAL B . n 
B 1 239 ASP 239 231 239 ASP ASP B . n 
B 1 240 PRO 240 232 240 PRO PRO B . n 
B 1 241 SER 241 233 241 SER SER B . n 
B 1 242 GLY 242 234 242 GLY GLY B . n 
B 1 243 LYS 243 235 243 LYS LYS B . n 
B 1 244 VAL 244 236 244 VAL VAL B . n 
B 1 245 VAL 245 237 245 VAL VAL B . n 
B 1 246 ARG 246 238 246 ARG ARG B . n 
B 1 247 ASP 247 239 247 ASP ASP B . n 
B 1 248 LEU 248 240 248 LEU LEU B . n 
B 1 249 TRP 249 241 249 TRP TRP B . n 
B 1 250 LEU 250 242 250 LEU LEU B . n 
B 1 251 GLU 251 243 251 GLU GLU B . n 
B 1 252 ALA 252 244 252 ALA ALA B . n 
B 1 253 PRO 253 245 253 PRO PRO B . n 
B 1 254 TRP 254 246 254 TRP TRP B . n 
B 1 255 CYS 255 247 255 CYS CYS B . n 
B 1 256 ALA 256 248 256 ALA ALA B . n 
B 1 257 PHE 257 249 257 PHE PHE B . n 
B 1 258 ILE 258 250 258 ILE ILE B . n 
B 1 259 HIS 259 251 259 HIS HIS B . n 
B 1 260 ASP 260 252 260 ASP ASP B . n 
B 1 261 CYS 261 253 261 CYS CYS B . n 
B 1 262 ALA 262 254 262 ALA ALA B . n 
B 1 263 LEU 263 255 263 LEU LEU B . n 
B 1 264 THR 264 256 264 THR THR B . n 
B 1 265 PRO 265 257 265 PRO PRO B . n 
B 1 266 ASN 266 258 266 ASN ASN B . n 
B 1 267 TYR 267 259 267 TYR TYR B . n 
B 1 268 LEU 268 260 268 LEU LEU B . n 
B 1 269 VAL 269 261 269 VAL VAL B . n 
B 1 270 LEU 270 262 270 LEU LEU B . n 
B 1 271 MET 271 263 271 MET MET B . n 
B 1 272 LEU 272 264 272 LEU LEU B . n 
B 1 273 TRP 273 265 273 TRP TRP B . n 
B 1 274 PRO 274 266 274 PRO PRO B . n 
B 1 275 PHE 275 267 275 PHE PHE B . n 
B 1 276 GLU 276 268 276 GLU GLU B . n 
B 1 277 ALA 277 269 277 ALA ALA B . n 
B 1 278 ASN 278 270 278 ASN ASN B . n 
B 1 279 LEU 279 271 279 LEU LEU B . n 
B 1 280 GLU 280 272 280 GLU GLU B . n 
B 1 281 ARG 281 273 281 ARG ARG B . n 
B 1 282 MET 282 274 282 MET MET B . n 
B 1 283 LYS 283 275 283 LYS LYS B . n 
B 1 284 ALA 284 276 284 ALA ALA B . n 
B 1 285 GLY 285 277 285 GLY GLY B . n 
B 1 286 GLY 286 278 286 GLY GLY B . n 
B 1 287 HIS 287 279 287 HIS HIS B . n 
B 1 288 HIS 288 280 288 HIS HIS B . n 
B 1 289 TRP 289 281 289 TRP TRP B . n 
B 1 290 ALA 290 282 290 ALA ALA B . n 
B 1 291 TYR 291 283 291 TYR TYR B . n 
B 1 292 ASP 292 284 292 ASP ASP B . n 
B 1 293 TYR 293 285 293 TYR TYR B . n 
B 1 294 THR 294 286 294 THR THR B . n 
B 1 295 LYS 295 287 295 LYS LYS B . n 
B 1 296 PRO 296 288 296 PRO PRO B . n 
B 1 297 ILE 297 289 297 ILE ILE B . n 
B 1 298 THR 298 290 298 THR THR B . n 
B 1 299 TRP 299 291 299 TRP TRP B . n 
B 1 300 ILE 300 292 300 ILE ILE B . n 
B 1 301 THR 301 293 301 THR THR B . n 
B 1 302 ILE 302 294 302 ILE ILE B . n 
B 1 303 PRO 303 295 303 PRO PRO B . n 
B 1 304 ARG 304 296 304 ARG ARG B . n 
B 1 305 GLY 305 297 305 GLY GLY B . n 
B 1 306 ALA 306 298 306 ALA ALA B . n 
B 1 307 LYS 307 299 307 LYS LYS B . n 
B 1 308 SER 308 300 308 SER SER B . n 
B 1 309 LYS 309 301 309 LYS LYS B . n 
B 1 310 ASP 310 302 310 ASP ASP B . n 
B 1 311 GLU 311 303 311 GLU GLU B . n 
B 1 312 VAL 312 304 312 VAL VAL B . n 
B 1 313 LYS 313 305 313 LYS LYS B . n 
B 1 314 TYR 314 306 314 TYR TYR B . n 
B 1 315 TRP 315 307 315 TRP TRP B . n 
B 1 316 HIS 316 308 316 HIS HIS B . n 
B 1 317 TRP 317 309 317 TRP TRP B . n 
B 1 318 LYS 318 310 318 LYS LYS B . n 
B 1 319 ASN 319 311 319 ASN ASN B . n 
B 1 320 GLY 320 312 320 GLY GLY B . n 
B 1 321 MET 321 313 321 MET MET B . n 
B 1 322 PRO 322 314 322 PRO PRO B . n 
B 1 323 ILE 323 315 323 ILE ILE B . n 
B 1 324 HIS 324 316 324 HIS HIS B . n 
B 1 325 THR 325 317 325 THR THR B . n 
B 1 326 ALA 326 318 326 ALA ALA B . n 
B 1 327 SER 327 319 327 SER SER B . n 
B 1 328 GLY 328 320 328 GLY GLY B . n 
B 1 329 PHE 329 321 329 PHE PHE B . n 
B 1 330 GLU 330 322 330 GLU GLU B . n 
B 1 331 ASP 331 323 331 ASP ASP B . n 
B 1 332 GLU 332 324 332 GLU GLU B . n 
B 1 333 GLN 333 325 333 GLN GLN B . n 
B 1 334 GLY 334 326 334 GLY GLY B . n 
B 1 335 ARG 335 327 335 ARG ARG B . n 
B 1 336 ILE 336 328 336 ILE ILE B . n 
B 1 337 ILE 337 329 337 ILE ILE B . n 
B 1 338 ILE 338 330 338 ILE ILE B . n 
B 1 339 ASP 339 331 339 ASP ASP B . n 
B 1 340 SER 340 332 340 SER SER B . n 
B 1 341 SER 341 333 341 SER SER B . n 
B 1 342 LEU 342 334 342 LEU LEU B . n 
B 1 343 VAL 343 335 343 VAL VAL B . n 
B 1 344 HIS 344 336 344 HIS HIS B . n 
B 1 345 GLY 345 337 345 GLY GLY B . n 
B 1 346 ASN 346 338 346 ASN ASN B . n 
B 1 347 ALA 347 339 347 ALA ALA B . n 
B 1 348 PHE 348 340 348 PHE PHE B . n 
B 1 349 PRO 349 341 349 PRO PRO B . n 
B 1 350 PHE 350 342 350 PHE PHE B . n 
B 1 351 PHE 351 343 351 PHE PHE B . n 
B 1 352 PRO 352 344 352 PRO PRO B . n 
B 1 353 PRO 353 345 353 PRO PRO B . n 
B 1 354 ASP 354 346 354 ASP ASP B . n 
B 1 355 SER 355 347 355 SER SER B . n 
B 1 356 ASP 356 348 356 ASP ASP B . n 
B 1 357 GLU 357 349 357 GLU GLU B . n 
B 1 358 GLN 358 350 358 GLN GLN B . n 
B 1 359 LYS 359 351 359 LYS LYS B . n 
B 1 360 LYS 360 352 360 LYS LYS B . n 
B 1 361 LYS 361 353 361 LYS LYS B . n 
B 1 362 GLN 362 354 362 GLN GLN B . n 
B 1 363 GLU 363 355 363 GLU GLU B . n 
B 1 364 ALA 364 356 364 ALA ALA B . n 
B 1 365 ASP 365 357 365 ASP ASP B . n 
B 1 366 GLY 366 358 366 GLY GLY B . n 
B 1 367 THR 367 359 367 THR THR B . n 
B 1 368 PRO 368 360 368 PRO PRO B . n 
B 1 369 LYS 369 361 369 LYS LYS B . n 
B 1 370 ALA 370 362 370 ALA ALA B . n 
B 1 371 GLN 371 363 371 GLN GLN B . n 
B 1 372 PHE 372 364 372 PHE PHE B . n 
B 1 373 VAL 373 365 373 VAL VAL B . n 
B 1 374 ARG 374 366 374 ARG ARG B . n 
B 1 375 TRP 375 367 375 TRP TRP B . n 
B 1 376 THR 376 368 376 THR THR B . n 
B 1 377 ILE 377 369 377 ILE ILE B . n 
B 1 378 ASP 378 370 378 ASP ASP B . n 
B 1 379 PRO 379 371 379 PRO PRO B . n 
B 1 380 ARG 380 372 380 ARG ARG B . n 
B 1 381 LYS 381 373 381 LYS LYS B . n 
B 1 382 ASP 382 374 382 ASP ASP B . n 
B 1 383 ASN 383 375 383 ASN ASN B . n 
B 1 384 ASN 384 376 384 ASN ASN B . n 
B 1 385 GLU 385 377 385 GLU GLU B . n 
B 1 386 GLN 386 378 386 GLN GLN B . n 
B 1 387 LEU 387 379 387 LEU LEU B . n 
B 1 388 PRO 388 380 388 PRO PRO B . n 
B 1 389 ASP 389 381 389 ASP ASP B . n 
B 1 390 PRO 390 382 390 PRO PRO B . n 
B 1 391 GLU 391 383 391 GLU GLU B . n 
B 1 392 VAL 392 384 392 VAL VAL B . n 
B 1 393 ILE 393 385 393 ILE ILE B . n 
B 1 394 LEU 394 386 394 LEU LEU B . n 
B 1 395 ASP 395 387 395 ASP ASP B . n 
B 1 396 THR 396 388 396 THR THR B . n 
B 1 397 PRO 397 389 397 PRO PRO B . n 
B 1 398 SER 398 390 398 SER SER B . n 
B 1 399 GLU 399 391 399 GLU GLU B . n 
B 1 400 PHE 400 392 400 PHE PHE B . n 
B 1 401 PRO 401 393 401 PRO PRO B . n 
B 1 402 GLN 402 394 402 GLN GLN B . n 
B 1 403 ILE 403 395 403 ILE ILE B . n 
B 1 404 ASP 404 396 404 ASP ASP B . n 
B 1 405 ASN 405 397 405 ASN ASN B . n 
B 1 406 ARG 406 398 406 ARG ARG B . n 
B 1 407 PHE 407 399 407 PHE PHE B . n 
B 1 408 MET 408 400 408 MET MET B . n 
B 1 409 GLY 409 401 409 GLY GLY B . n 
B 1 410 VAL 410 402 410 VAL VAL B . n 
B 1 411 GLU 411 403 411 GLU GLU B . n 
B 1 412 TYR 412 404 412 TYR TYR B . n 
B 1 413 SER 413 405 413 SER SER B . n 
B 1 414 SER 414 406 414 SER SER B . n 
B 1 415 ALA 415 407 415 ALA ALA B . n 
B 1 416 PHE 416 408 416 PHE PHE B . n 
B 1 417 ILE 417 409 417 ILE ILE B . n 
B 1 418 ASN 418 410 418 ASN ASN B . n 
B 1 419 VAL 419 411 419 VAL VAL B . n 
B 1 420 PHE 420 412 420 PHE PHE B . n 
B 1 421 VAL 421 413 421 VAL VAL B . n 
B 1 422 PRO 422 414 422 PRO PRO B . n 
B 1 423 ASP 423 415 423 ASP ASP B . n 
B 1 424 ARG 424 416 424 ARG ARG B . n 
B 1 425 SER 425 417 425 SER SER B . n 
B 1 426 ASP 426 418 426 ASP ASP B . n 
B 1 427 GLY 427 419 427 GLY GLY B . n 
B 1 428 ASN 428 420 428 ASN ASN B . n 
B 1 429 LYS 429 421 429 LYS LYS B . n 
B 1 430 ASN 430 422 430 ASN ASN B . n 
B 1 431 VAL 431 423 431 VAL VAL B . n 
B 1 432 PHE 432 424 432 PHE PHE B . n 
B 1 433 GLN 433 425 433 GLN GLN B . n 
B 1 434 GLY 434 426 434 GLY GLY B . n 
B 1 435 LEU 435 427 435 LEU LEU B . n 
B 1 436 ASN 436 428 436 ASN ASN B . n 
B 1 437 GLY 437 429 437 GLY GLY B . n 
B 1 438 LEU 438 430 438 LEU LEU B . n 
B 1 439 ALA 439 431 439 ALA ALA B . n 
B 1 440 HIS 440 432 440 HIS HIS B . n 
B 1 441 TYR 441 433 441 TYR TYR B . n 
B 1 442 LYS 442 434 442 LYS LYS B . n 
B 1 443 ARG 443 435 443 ARG ARG B . n 
B 1 444 LYS 444 436 444 LYS LYS B . n 
B 1 445 GLU 445 437 445 GLU GLU B . n 
B 1 446 GLY 446 438 446 GLY GLY B . n 
B 1 447 THR 447 439 447 THR THR B . n 
B 1 448 THR 448 440 448 THR THR B . n 
B 1 449 GLU 449 441 449 GLU GLU B . n 
B 1 450 TRP 450 442 450 TRP TRP B . n 
B 1 451 TYR 451 443 451 TYR TYR B . n 
B 1 452 TYR 452 444 452 TYR TYR B . n 
B 1 453 ALA 453 445 453 ALA ALA B . n 
B 1 454 GLY 454 446 454 GLY GLY B . n 
B 1 455 ASP 455 447 455 ASP ASP B . n 
B 1 456 ASN 456 448 456 ASN ASN B . n 
B 1 457 CYS 457 449 457 CYS CYS B . n 
B 1 458 LEU 458 450 458 LEU LEU B . n 
B 1 459 ILE 459 451 459 ILE ILE B . n 
B 1 460 GLN 460 452 460 GLN GLN B . n 
B 1 461 GLU 461 453 461 GLU GLU B . n 
B 1 462 PRO 462 454 462 PRO PRO B . n 
B 1 463 VAL 463 455 463 VAL VAL B . n 
B 1 464 PHE 464 456 464 PHE PHE B . n 
B 1 465 SER 465 457 465 SER SER B . n 
B 1 466 PRO 466 458 466 PRO PRO B . n 
B 1 467 ARG 467 459 467 ARG ARG B . n 
B 1 468 SER 468 460 468 SER SER B . n 
B 1 469 LYS 469 461 469 LYS LYS B . n 
B 1 470 ASP 470 462 470 ASP ASP B . n 
B 1 471 ALA 471 463 471 ALA ALA B . n 
B 1 472 PRO 472 464 472 PRO PRO B . n 
B 1 473 GLU 473 465 473 GLU GLU B . n 
B 1 474 GLY 474 466 474 GLY GLY B . n 
B 1 475 ASP 475 467 475 ASP ASP B . n 
B 1 476 GLY 476 468 476 GLY GLY B . n 
B 1 477 PHE 477 469 477 PHE PHE B . n 
B 1 478 VAL 478 470 478 VAL VAL B . n 
B 1 479 LEU 479 471 479 LEU LEU B . n 
B 1 480 ALA 480 472 480 ALA ALA B . n 
B 1 481 ILE 481 473 481 ILE ILE B . n 
B 1 482 VAL 482 474 482 VAL VAL B . n 
B 1 483 ASP 483 475 483 ASP ASP B . n 
B 1 484 ARG 484 476 484 ARG ARG B . n 
B 1 485 LEU 485 477 485 LEU LEU B . n 
B 1 486 ASP 486 478 486 ASP ASP B . n 
B 1 487 LEU 487 479 487 LEU LEU B . n 
B 1 488 ASN 488 480 488 ASN ASN B . n 
B 1 489 ARG 489 481 489 ARG ARG B . n 
B 1 490 SER 490 482 490 SER SER B . n 
B 1 491 GLU 491 483 491 GLU GLU B . n 
B 1 492 VAL 492 484 492 VAL VAL B . n 
B 1 493 VAL 493 485 493 VAL VAL B . n 
B 1 494 VAL 494 486 494 VAL VAL B . n 
B 1 495 ILE 495 487 495 ILE ILE B . n 
B 1 496 ASP 496 488 496 ASP ASP B . n 
B 1 497 THR 497 489 497 THR THR B . n 
B 1 498 ARG 498 490 498 ARG ARG B . n 
B 1 499 ASP 499 491 499 ASP ASP B . n 
B 1 500 PHE 500 492 500 PHE PHE B . n 
B 1 501 THR 501 493 501 THR THR B . n 
B 1 502 LYS 502 494 502 LYS LYS B . n 
B 1 503 ALA 503 495 503 ALA ALA B . n 
B 1 504 VAL 504 496 504 VAL VAL B . n 
B 1 505 ALA 505 497 505 ALA ALA B . n 
B 1 506 ALA 506 498 506 ALA ALA B . n 
B 1 507 VAL 507 499 507 VAL VAL B . n 
B 1 508 GLN 508 500 508 GLN GLN B . n 
B 1 509 LEU 509 501 509 LEU LEU B . n 
B 1 510 PRO 510 502 510 PRO PRO B . n 
B 1 511 PHE 511 503 511 PHE PHE B . n 
B 1 512 ALA 512 504 512 ALA ALA B . n 
B 1 513 ILE 513 505 513 ILE ILE B . n 
B 1 514 ARG 514 506 514 ARG ARG B . n 
B 1 515 SER 515 507 515 SER SER B . n 
B 1 516 GLY 516 508 516 GLY GLY B . n 
B 1 517 ILE 517 509 517 ILE ILE B . n 
B 1 518 HIS 518 510 518 HIS HIS B . n 
B 1 519 GLY 519 511 519 GLY GLY B . n 
B 1 520 GLN 520 512 520 GLN GLN B . n 
B 1 521 TRP 521 513 521 TRP TRP B . n 
B 1 522 ILE 522 514 522 ILE ILE B . n 
B 1 523 PRO 523 515 523 PRO PRO B . n 
B 1 524 GLY 524 516 524 GLY GLY B . n 
B 1 525 GLU 525 517 525 GLU GLU B . n 
B 1 526 VAL 526 518 526 VAL VAL B . n 
B 1 527 THR 527 519 527 THR THR B . n 
B 1 528 PRO 528 520 528 PRO PRO B . n 
B 1 529 ASP 529 521 529 ASP ASP B . n 
B 1 530 PHE 530 522 530 PHE PHE B . n 
B 1 531 GLU 531 523 531 GLU GLU B . n 
B 1 532 THR 532 524 532 THR THR B . n 
B 1 533 LYS 533 525 533 LYS LYS B . n 
B 1 534 GLY 534 526 534 GLY GLY B . n 
B 1 535 LEU 535 527 535 LEU LEU B . n 
B 1 536 VAL 536 528 536 VAL VAL B . n 
B 1 537 ASP 537 529 537 ASP ASP B . n 
B 1 538 LEU 538 530 538 LEU LEU B . n 
B 1 539 PRO 539 531 539 PRO PRO B . n 
B 1 540 LYS 540 532 540 LYS LYS B . n 
B 1 541 GLU 541 533 541 GLU GLU B . n 
B 1 542 GLU 542 534 542 GLU GLU B . n 
B 1 543 HIS 543 535 543 HIS HIS B . n 
B 1 544 TRP 544 536 544 TRP TRP B . n 
B 1 545 ALA 545 537 545 ALA ALA B . n 
B 1 546 PRO 546 538 546 PRO PRO B . n 
B 1 547 LEU 547 539 547 LEU LEU B . n 
B 1 548 SER 548 540 548 SER SER B . n 
B 1 549 GLN 549 541 549 GLN GLN B . n 
B 1 550 SER 550 542 550 SER SER B . n 
B 1 551 PRO 551 543 551 PRO PRO B . n 
B 1 552 TYR 552 544 552 TYR TYR B . n 
B 1 553 ASP 553 545 553 ASP ASP B . n 
B 1 554 PRO 554 546 554 PRO PRO B . n 
B 1 555 ASP 555 547 555 ASP ASP B . n 
B 1 556 ALA 556 548 556 ALA ALA B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 V55 ? ? V55 ? ? 'SUBJECT OF INVESTIGATION' ? 
2 FE2 ? ? FE2 ? ? 'SUBJECT OF INVESTIGATION' ? 
3 GOL ? ? GOL ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 V55 1   601  601 V55 00Z A . 
D 3 GOL 1   602  602 GOL GOL A . 
E 3 GOL 1   603  603 GOL GOL A . 
F 3 GOL 1   604  604 GOL GOL A . 
G 3 GOL 1   605  605 GOL GOL A . 
H 3 GOL 1   606  701 GOL GOL A . 
I 4 FE2 1   607  1   FE2 FE  A . 
J 2 V55 1   601  601 V55 00Z B . 
K 3 GOL 1   602  602 GOL GOL B . 
L 4 FE2 1   603  2   FE2 FE  B . 
M 5 HOH 1   701  343 HOH HOH A . 
M 5 HOH 2   702  459 HOH HOH A . 
M 5 HOH 3   703  435 HOH HOH A . 
M 5 HOH 4   704  862 HOH HOH A . 
M 5 HOH 5   705  496 HOH HOH A . 
M 5 HOH 6   706  363 HOH HOH A . 
M 5 HOH 7   707  633 HOH HOH A . 
M 5 HOH 8   708  884 HOH HOH A . 
M 5 HOH 9   709  358 HOH HOH A . 
M 5 HOH 10  710  418 HOH HOH A . 
M 5 HOH 11  711  349 HOH HOH A . 
M 5 HOH 12  712  400 HOH HOH A . 
M 5 HOH 13  713  702 HOH HOH A . 
M 5 HOH 14  714  436 HOH HOH A . 
M 5 HOH 15  715  429 HOH HOH A . 
M 5 HOH 16  716  538 HOH HOH A . 
M 5 HOH 17  717  790 HOH HOH A . 
M 5 HOH 18  718  48  HOH HOH A . 
M 5 HOH 19  719  592 HOH HOH A . 
M 5 HOH 20  720  518 HOH HOH A . 
M 5 HOH 21  721  280 HOH HOH A . 
M 5 HOH 22  722  294 HOH HOH A . 
M 5 HOH 23  723  836 HOH HOH A . 
M 5 HOH 24  724  848 HOH HOH A . 
M 5 HOH 25  725  395 HOH HOH A . 
M 5 HOH 26  726  151 HOH HOH A . 
M 5 HOH 27  727  412 HOH HOH A . 
M 5 HOH 28  728  125 HOH HOH A . 
M 5 HOH 29  729  262 HOH HOH A . 
M 5 HOH 30  730  296 HOH HOH A . 
M 5 HOH 31  731  565 HOH HOH A . 
M 5 HOH 32  732  130 HOH HOH A . 
M 5 HOH 33  733  329 HOH HOH A . 
M 5 HOH 34  734  691 HOH HOH A . 
M 5 HOH 35  735  340 HOH HOH A . 
M 5 HOH 36  736  681 HOH HOH A . 
M 5 HOH 37  737  16  HOH HOH A . 
M 5 HOH 38  738  856 HOH HOH A . 
M 5 HOH 39  739  425 HOH HOH A . 
M 5 HOH 40  740  687 HOH HOH A . 
M 5 HOH 41  741  203 HOH HOH A . 
M 5 HOH 42  742  778 HOH HOH A . 
M 5 HOH 43  743  545 HOH HOH A . 
M 5 HOH 44  744  177 HOH HOH A . 
M 5 HOH 45  745  535 HOH HOH A . 
M 5 HOH 46  746  673 HOH HOH A . 
M 5 HOH 47  747  366 HOH HOH A . 
M 5 HOH 48  748  581 HOH HOH A . 
M 5 HOH 49  749  490 HOH HOH A . 
M 5 HOH 50  750  17  HOH HOH A . 
M 5 HOH 51  751  764 HOH HOH A . 
M 5 HOH 52  752  336 HOH HOH A . 
M 5 HOH 53  753  619 HOH HOH A . 
M 5 HOH 54  754  745 HOH HOH A . 
M 5 HOH 55  755  33  HOH HOH A . 
M 5 HOH 56  756  552 HOH HOH A . 
M 5 HOH 57  757  50  HOH HOH A . 
M 5 HOH 58  758  660 HOH HOH A . 
M 5 HOH 59  759  224 HOH HOH A . 
M 5 HOH 60  760  855 HOH HOH A . 
M 5 HOH 61  761  817 HOH HOH A . 
M 5 HOH 62  762  865 HOH HOH A . 
M 5 HOH 63  763  582 HOH HOH A . 
M 5 HOH 64  764  113 HOH HOH A . 
M 5 HOH 65  765  761 HOH HOH A . 
M 5 HOH 66  766  178 HOH HOH A . 
M 5 HOH 67  767  271 HOH HOH A . 
M 5 HOH 68  768  409 HOH HOH A . 
M 5 HOH 69  769  301 HOH HOH A . 
M 5 HOH 70  770  534 HOH HOH A . 
M 5 HOH 71  771  156 HOH HOH A . 
M 5 HOH 72  772  464 HOH HOH A . 
M 5 HOH 73  773  238 HOH HOH A . 
M 5 HOH 74  774  740 HOH HOH A . 
M 5 HOH 75  775  84  HOH HOH A . 
M 5 HOH 76  776  876 HOH HOH A . 
M 5 HOH 77  777  370 HOH HOH A . 
M 5 HOH 78  778  627 HOH HOH A . 
M 5 HOH 79  779  617 HOH HOH A . 
M 5 HOH 80  780  461 HOH HOH A . 
M 5 HOH 81  781  193 HOH HOH A . 
M 5 HOH 82  782  750 HOH HOH A . 
M 5 HOH 83  783  117 HOH HOH A . 
M 5 HOH 84  784  275 HOH HOH A . 
M 5 HOH 85  785  655 HOH HOH A . 
M 5 HOH 86  786  270 HOH HOH A . 
M 5 HOH 87  787  840 HOH HOH A . 
M 5 HOH 88  788  326 HOH HOH A . 
M 5 HOH 89  789  297 HOH HOH A . 
M 5 HOH 90  790  232 HOH HOH A . 
M 5 HOH 91  791  114 HOH HOH A . 
M 5 HOH 92  792  304 HOH HOH A . 
M 5 HOH 93  793  380 HOH HOH A . 
M 5 HOH 94  794  141 HOH HOH A . 
M 5 HOH 95  795  26  HOH HOH A . 
M 5 HOH 96  796  796 HOH HOH A . 
M 5 HOH 97  797  23  HOH HOH A . 
M 5 HOH 98  798  844 HOH HOH A . 
M 5 HOH 99  799  374 HOH HOH A . 
M 5 HOH 100 800  77  HOH HOH A . 
M 5 HOH 101 801  39  HOH HOH A . 
M 5 HOH 102 802  396 HOH HOH A . 
M 5 HOH 103 803  86  HOH HOH A . 
M 5 HOH 104 804  199 HOH HOH A . 
M 5 HOH 105 805  389 HOH HOH A . 
M 5 HOH 106 806  495 HOH HOH A . 
M 5 HOH 107 807  268 HOH HOH A . 
M 5 HOH 108 808  784 HOH HOH A . 
M 5 HOH 109 809  663 HOH HOH A . 
M 5 HOH 110 810  743 HOH HOH A . 
M 5 HOH 111 811  849 HOH HOH A . 
M 5 HOH 112 812  192 HOH HOH A . 
M 5 HOH 113 813  173 HOH HOH A . 
M 5 HOH 114 814  831 HOH HOH A . 
M 5 HOH 115 815  874 HOH HOH A . 
M 5 HOH 116 816  129 HOH HOH A . 
M 5 HOH 117 817  600 HOH HOH A . 
M 5 HOH 118 818  144 HOH HOH A . 
M 5 HOH 119 819  140 HOH HOH A . 
M 5 HOH 120 820  491 HOH HOH A . 
M 5 HOH 121 821  622 HOH HOH A . 
M 5 HOH 122 822  734 HOH HOH A . 
M 5 HOH 123 823  68  HOH HOH A . 
M 5 HOH 124 824  295 HOH HOH A . 
M 5 HOH 125 825  727 HOH HOH A . 
M 5 HOH 126 826  371 HOH HOH A . 
M 5 HOH 127 827  202 HOH HOH A . 
M 5 HOH 128 828  472 HOH HOH A . 
M 5 HOH 129 829  465 HOH HOH A . 
M 5 HOH 130 830  105 HOH HOH A . 
M 5 HOH 131 831  269 HOH HOH A . 
M 5 HOH 132 832  131 HOH HOH A . 
M 5 HOH 133 833  175 HOH HOH A . 
M 5 HOH 134 834  520 HOH HOH A . 
M 5 HOH 135 835  187 HOH HOH A . 
M 5 HOH 136 836  315 HOH HOH A . 
M 5 HOH 137 837  264 HOH HOH A . 
M 5 HOH 138 838  547 HOH HOH A . 
M 5 HOH 139 839  330 HOH HOH A . 
M 5 HOH 140 840  176 HOH HOH A . 
M 5 HOH 141 841  161 HOH HOH A . 
M 5 HOH 142 842  348 HOH HOH A . 
M 5 HOH 143 843  136 HOH HOH A . 
M 5 HOH 144 844  9   HOH HOH A . 
M 5 HOH 145 845  504 HOH HOH A . 
M 5 HOH 146 846  327 HOH HOH A . 
M 5 HOH 147 847  618 HOH HOH A . 
M 5 HOH 148 848  205 HOH HOH A . 
M 5 HOH 149 849  628 HOH HOH A . 
M 5 HOH 150 850  53  HOH HOH A . 
M 5 HOH 151 851  19  HOH HOH A . 
M 5 HOH 152 852  559 HOH HOH A . 
M 5 HOH 153 853  508 HOH HOH A . 
M 5 HOH 154 854  667 HOH HOH A . 
M 5 HOH 155 855  385 HOH HOH A . 
M 5 HOH 156 856  185 HOH HOH A . 
M 5 HOH 157 857  22  HOH HOH A . 
M 5 HOH 158 858  379 HOH HOH A . 
M 5 HOH 159 859  466 HOH HOH A . 
M 5 HOH 160 860  864 HOH HOH A . 
M 5 HOH 161 861  511 HOH HOH A . 
M 5 HOH 162 862  215 HOH HOH A . 
M 5 HOH 163 863  283 HOH HOH A . 
M 5 HOH 164 864  25  HOH HOH A . 
M 5 HOH 165 865  851 HOH HOH A . 
M 5 HOH 166 866  94  HOH HOH A . 
M 5 HOH 167 867  7   HOH HOH A . 
M 5 HOH 168 868  685 HOH HOH A . 
M 5 HOH 169 869  89  HOH HOH A . 
M 5 HOH 170 870  237 HOH HOH A . 
M 5 HOH 171 871  834 HOH HOH A . 
M 5 HOH 172 872  27  HOH HOH A . 
M 5 HOH 173 873  625 HOH HOH A . 
M 5 HOH 174 874  139 HOH HOH A . 
M 5 HOH 175 875  577 HOH HOH A . 
M 5 HOH 176 876  833 HOH HOH A . 
M 5 HOH 177 877  710 HOH HOH A . 
M 5 HOH 178 878  376 HOH HOH A . 
M 5 HOH 179 879  391 HOH HOH A . 
M 5 HOH 180 880  473 HOH HOH A . 
M 5 HOH 181 881  300 HOH HOH A . 
M 5 HOH 182 882  152 HOH HOH A . 
M 5 HOH 183 883  331 HOH HOH A . 
M 5 HOH 184 884  75  HOH HOH A . 
M 5 HOH 185 885  134 HOH HOH A . 
M 5 HOH 186 886  123 HOH HOH A . 
M 5 HOH 187 887  206 HOH HOH A . 
M 5 HOH 188 888  420 HOH HOH A . 
M 5 HOH 189 889  162 HOH HOH A . 
M 5 HOH 190 890  711 HOH HOH A . 
M 5 HOH 191 891  267 HOH HOH A . 
M 5 HOH 192 892  66  HOH HOH A . 
M 5 HOH 193 893  201 HOH HOH A . 
M 5 HOH 194 894  888 HOH HOH A . 
M 5 HOH 195 895  85  HOH HOH A . 
M 5 HOH 196 896  889 HOH HOH A . 
M 5 HOH 197 897  149 HOH HOH A . 
M 5 HOH 198 898  654 HOH HOH A . 
M 5 HOH 199 899  61  HOH HOH A . 
M 5 HOH 200 900  56  HOH HOH A . 
M 5 HOH 201 901  67  HOH HOH A . 
M 5 HOH 202 902  272 HOH HOH A . 
M 5 HOH 203 903  328 HOH HOH A . 
M 5 HOH 204 904  82  HOH HOH A . 
M 5 HOH 205 905  403 HOH HOH A . 
M 5 HOH 206 906  367 HOH HOH A . 
M 5 HOH 207 907  882 HOH HOH A . 
M 5 HOH 208 908  478 HOH HOH A . 
M 5 HOH 209 909  40  HOH HOH A . 
M 5 HOH 210 910  672 HOH HOH A . 
M 5 HOH 211 911  43  HOH HOH A . 
M 5 HOH 212 912  18  HOH HOH A . 
M 5 HOH 213 913  568 HOH HOH A . 
M 5 HOH 214 914  6   HOH HOH A . 
M 5 HOH 215 915  438 HOH HOH A . 
M 5 HOH 216 916  769 HOH HOH A . 
M 5 HOH 217 917  325 HOH HOH A . 
M 5 HOH 218 918  868 HOH HOH A . 
M 5 HOH 219 919  695 HOH HOH A . 
M 5 HOH 220 920  821 HOH HOH A . 
M 5 HOH 221 921  519 HOH HOH A . 
M 5 HOH 222 922  594 HOH HOH A . 
M 5 HOH 223 923  835 HOH HOH A . 
M 5 HOH 224 924  732 HOH HOH A . 
M 5 HOH 225 925  656 HOH HOH A . 
M 5 HOH 226 926  188 HOH HOH A . 
M 5 HOH 227 927  457 HOH HOH A . 
M 5 HOH 228 928  890 HOH HOH A . 
M 5 HOH 229 929  462 HOH HOH A . 
M 5 HOH 230 930  593 HOH HOH A . 
M 5 HOH 231 931  339 HOH HOH A . 
M 5 HOH 232 932  287 HOH HOH A . 
M 5 HOH 233 933  211 HOH HOH A . 
M 5 HOH 234 934  596 HOH HOH A . 
M 5 HOH 235 935  183 HOH HOH A . 
M 5 HOH 236 936  554 HOH HOH A . 
M 5 HOH 237 937  388 HOH HOH A . 
M 5 HOH 238 938  448 HOH HOH A . 
M 5 HOH 239 939  107 HOH HOH A . 
M 5 HOH 240 940  608 HOH HOH A . 
M 5 HOH 241 941  158 HOH HOH A . 
M 5 HOH 242 942  99  HOH HOH A . 
M 5 HOH 243 943  228 HOH HOH A . 
M 5 HOH 244 944  1   HOH HOH A . 
M 5 HOH 245 945  398 HOH HOH A . 
M 5 HOH 246 946  263 HOH HOH A . 
M 5 HOH 247 947  314 HOH HOH A . 
M 5 HOH 248 948  580 HOH HOH A . 
M 5 HOH 249 949  244 HOH HOH A . 
M 5 HOH 250 950  103 HOH HOH A . 
M 5 HOH 251 951  406 HOH HOH A . 
M 5 HOH 252 952  479 HOH HOH A . 
M 5 HOH 253 953  550 HOH HOH A . 
M 5 HOH 254 954  132 HOH HOH A . 
M 5 HOH 255 955  854 HOH HOH A . 
M 5 HOH 256 956  602 HOH HOH A . 
M 5 HOH 257 957  282 HOH HOH A . 
M 5 HOH 258 958  72  HOH HOH A . 
M 5 HOH 259 959  542 HOH HOH A . 
M 5 HOH 260 960  560 HOH HOH A . 
M 5 HOH 261 961  394 HOH HOH A . 
M 5 HOH 262 962  443 HOH HOH A . 
M 5 HOH 263 963  142 HOH HOH A . 
M 5 HOH 264 964  850 HOH HOH A . 
M 5 HOH 265 965  170 HOH HOH A . 
M 5 HOH 266 966  720 HOH HOH A . 
M 5 HOH 267 967  822 HOH HOH A . 
M 5 HOH 268 968  649 HOH HOH A . 
M 5 HOH 269 969  393 HOH HOH A . 
M 5 HOH 270 970  442 HOH HOH A . 
M 5 HOH 271 971  768 HOH HOH A . 
M 5 HOH 272 972  718 HOH HOH A . 
M 5 HOH 273 973  432 HOH HOH A . 
M 5 HOH 274 974  390 HOH HOH A . 
M 5 HOH 275 975  150 HOH HOH A . 
M 5 HOH 276 976  313 HOH HOH A . 
M 5 HOH 277 977  250 HOH HOH A . 
M 5 HOH 278 978  721 HOH HOH A . 
M 5 HOH 279 979  169 HOH HOH A . 
M 5 HOH 280 980  407 HOH HOH A . 
M 5 HOH 281 981  715 HOH HOH A . 
M 5 HOH 282 982  189 HOH HOH A . 
M 5 HOH 283 983  278 HOH HOH A . 
M 5 HOH 284 984  281 HOH HOH A . 
M 5 HOH 285 985  338 HOH HOH A . 
M 5 HOH 286 986  639 HOH HOH A . 
M 5 HOH 287 987  293 HOH HOH A . 
M 5 HOH 288 988  753 HOH HOH A . 
M 5 HOH 289 989  261 HOH HOH A . 
M 5 HOH 290 990  73  HOH HOH A . 
M 5 HOH 291 991  467 HOH HOH A . 
M 5 HOH 292 992  42  HOH HOH A . 
M 5 HOH 293 993  217 HOH HOH A . 
M 5 HOH 294 994  81  HOH HOH A . 
M 5 HOH 295 995  521 HOH HOH A . 
M 5 HOH 296 996  186 HOH HOH A . 
M 5 HOH 297 997  588 HOH HOH A . 
M 5 HOH 298 998  197 HOH HOH A . 
M 5 HOH 299 999  38  HOH HOH A . 
M 5 HOH 300 1000 522 HOH HOH A . 
M 5 HOH 301 1001 675 HOH HOH A . 
M 5 HOH 302 1002 516 HOH HOH A . 
M 5 HOH 303 1003 468 HOH HOH A . 
M 5 HOH 304 1004 638 HOH HOH A . 
M 5 HOH 305 1005 866 HOH HOH A . 
M 5 HOH 306 1006 110 HOH HOH A . 
M 5 HOH 307 1007 116 HOH HOH A . 
M 5 HOH 308 1008 871 HOH HOH A . 
M 5 HOH 309 1009 795 HOH HOH A . 
M 5 HOH 310 1010 46  HOH HOH A . 
M 5 HOH 311 1011 417 HOH HOH A . 
M 5 HOH 312 1012 37  HOH HOH A . 
M 5 HOH 313 1013 557 HOH HOH A . 
M 5 HOH 314 1014 575 HOH HOH A . 
M 5 HOH 315 1015 210 HOH HOH A . 
M 5 HOH 316 1016 843 HOH HOH A . 
M 5 HOH 317 1017 305 HOH HOH A . 
M 5 HOH 318 1018 196 HOH HOH A . 
M 5 HOH 319 1019 421 HOH HOH A . 
M 5 HOH 320 1020 378 HOH HOH A . 
M 5 HOH 321 1021 2   HOH HOH A . 
M 5 HOH 322 1022 322 HOH HOH A . 
M 5 HOH 323 1023 427 HOH HOH A . 
M 5 HOH 324 1024 487 HOH HOH A . 
M 5 HOH 325 1025 277 HOH HOH A . 
M 5 HOH 326 1026 742 HOH HOH A . 
M 5 HOH 327 1027 782 HOH HOH A . 
M 5 HOH 328 1028 309 HOH HOH A . 
M 5 HOH 329 1029 694 HOH HOH A . 
M 5 HOH 330 1030 303 HOH HOH A . 
M 5 HOH 331 1031 730 HOH HOH A . 
M 5 HOH 332 1032 397 HOH HOH A . 
M 5 HOH 333 1033 620 HOH HOH A . 
M 5 HOH 334 1034 546 HOH HOH A . 
M 5 HOH 335 1035 434 HOH HOH A . 
M 5 HOH 336 1036 497 HOH HOH A . 
M 5 HOH 337 1037 359 HOH HOH A . 
M 5 HOH 338 1038 482 HOH HOH A . 
M 5 HOH 339 1039 869 HOH HOH A . 
M 5 HOH 340 1040 775 HOH HOH A . 
M 5 HOH 341 1041 28  HOH HOH A . 
M 5 HOH 342 1042 242 HOH HOH A . 
M 5 HOH 343 1043 424 HOH HOH A . 
M 5 HOH 344 1044 635 HOH HOH A . 
M 5 HOH 345 1045 447 HOH HOH A . 
M 5 HOH 346 1046 191 HOH HOH A . 
M 5 HOH 347 1047 433 HOH HOH A . 
M 5 HOH 348 1048 133 HOH HOH A . 
M 5 HOH 349 1049 115 HOH HOH A . 
M 5 HOH 350 1050 316 HOH HOH A . 
M 5 HOH 351 1051 10  HOH HOH A . 
M 5 HOH 352 1052 788 HOH HOH A . 
M 5 HOH 353 1053 713 HOH HOH A . 
M 5 HOH 354 1054 562 HOH HOH A . 
M 5 HOH 355 1055 306 HOH HOH A . 
M 5 HOH 356 1056 657 HOH HOH A . 
M 5 HOH 357 1057 503 HOH HOH A . 
M 5 HOH 358 1058 124 HOH HOH A . 
M 5 HOH 359 1059 71  HOH HOH A . 
M 5 HOH 360 1060 194 HOH HOH A . 
M 5 HOH 361 1061 789 HOH HOH A . 
M 5 HOH 362 1062 760 HOH HOH A . 
M 5 HOH 363 1063 147 HOH HOH A . 
M 5 HOH 364 1064 722 HOH HOH A . 
M 5 HOH 365 1065 688 HOH HOH A . 
M 5 HOH 366 1066 45  HOH HOH A . 
M 5 HOH 367 1067 674 HOH HOH A . 
M 5 HOH 368 1068 59  HOH HOH A . 
M 5 HOH 369 1069 603 HOH HOH A . 
M 5 HOH 370 1070 870 HOH HOH A . 
M 5 HOH 371 1071 708 HOH HOH A . 
M 5 HOH 372 1072 486 HOH HOH A . 
M 5 HOH 373 1073 698 HOH HOH A . 
M 5 HOH 374 1074 794 HOH HOH A . 
M 5 HOH 375 1075 611 HOH HOH A . 
M 5 HOH 376 1076 692 HOH HOH A . 
M 5 HOH 377 1077 825 HOH HOH A . 
M 5 HOH 378 1078 441 HOH HOH A . 
M 5 HOH 379 1079 34  HOH HOH A . 
M 5 HOH 380 1080 579 HOH HOH A . 
M 5 HOH 381 1081 875 HOH HOH A . 
M 5 HOH 382 1082 610 HOH HOH A . 
M 5 HOH 383 1083 572 HOH HOH A . 
M 5 HOH 384 1084 739 HOH HOH A . 
M 5 HOH 385 1085 344 HOH HOH A . 
M 5 HOH 386 1086 787 HOH HOH A . 
M 5 HOH 387 1087 773 HOH HOH A . 
M 5 HOH 388 1088 399 HOH HOH A . 
M 5 HOH 389 1089 793 HOH HOH A . 
M 5 HOH 390 1090 693 HOH HOH A . 
M 5 HOH 391 1091 590 HOH HOH A . 
M 5 HOH 392 1092 213 HOH HOH A . 
M 5 HOH 393 1093 812 HOH HOH A . 
M 5 HOH 394 1094 506 HOH HOH A . 
M 5 HOH 395 1095 428 HOH HOH A . 
M 5 HOH 396 1096 752 HOH HOH A . 
M 5 HOH 397 1097 659 HOH HOH A . 
M 5 HOH 398 1098 804 HOH HOH A . 
M 5 HOH 399 1099 823 HOH HOH A . 
M 5 HOH 400 1100 489 HOH HOH A . 
M 5 HOH 401 1101 805 HOH HOH A . 
M 5 HOH 402 1102 569 HOH HOH A . 
M 5 HOH 403 1103 570 HOH HOH A . 
M 5 HOH 404 1104 827 HOH HOH A . 
M 5 HOH 405 1105 829 HOH HOH A . 
M 5 HOH 406 1106 404 HOH HOH A . 
M 5 HOH 407 1107 613 HOH HOH A . 
M 5 HOH 408 1108 64  HOH HOH A . 
M 5 HOH 409 1109 485 HOH HOH A . 
M 5 HOH 410 1110 803 HOH HOH A . 
M 5 HOH 411 1111 644 HOH HOH A . 
M 5 HOH 412 1112 265 HOH HOH A . 
M 5 HOH 413 1113 801 HOH HOH A . 
M 5 HOH 414 1114 544 HOH HOH A . 
M 5 HOH 415 1115 493 HOH HOH A . 
M 5 HOH 416 1116 807 HOH HOH A . 
M 5 HOH 417 1117 766 HOH HOH A . 
M 5 HOH 418 1118 451 HOH HOH A . 
M 5 HOH 419 1119 806 HOH HOH A . 
M 5 HOH 420 1120 352 HOH HOH A . 
M 5 HOH 421 1121 528 HOH HOH A . 
M 5 HOH 422 1122 607 HOH HOH A . 
M 5 HOH 423 1123 357 HOH HOH A . 
M 5 HOH 424 1124 606 HOH HOH A . 
M 5 HOH 425 1125 274 HOH HOH A . 
M 5 HOH 426 1126 410 HOH HOH A . 
M 5 HOH 427 1127 310 HOH HOH A . 
M 5 HOH 428 1128 463 HOH HOH A . 
M 5 HOH 429 1129 480 HOH HOH A . 
M 5 HOH 430 1130 800 HOH HOH A . 
M 5 HOH 431 1131 549 HOH HOH A . 
M 5 HOH 432 1132 666 HOH HOH A . 
M 5 HOH 433 1133 510 HOH HOH A . 
N 5 HOH 1   701  679 HOH HOH B . 
N 5 HOH 2   702  154 HOH HOH B . 
N 5 HOH 3   703  717 HOH HOH B . 
N 5 HOH 4   704  665 HOH HOH B . 
N 5 HOH 5   705  714 HOH HOH B . 
N 5 HOH 6   706  664 HOH HOH B . 
N 5 HOH 7   707  460 HOH HOH B . 
N 5 HOH 8   708  571 HOH HOH B . 
N 5 HOH 9   709  573 HOH HOH B . 
N 5 HOH 10  710  725 HOH HOH B . 
N 5 HOH 11  711  341 HOH HOH B . 
N 5 HOH 12  712  629 HOH HOH B . 
N 5 HOH 13  713  615 HOH HOH B . 
N 5 HOH 14  714  285 HOH HOH B . 
N 5 HOH 15  715  229 HOH HOH B . 
N 5 HOH 16  716  832 HOH HOH B . 
N 5 HOH 17  717  892 HOH HOH B . 
N 5 HOH 18  718  260 HOH HOH B . 
N 5 HOH 19  719  257 HOH HOH B . 
N 5 HOH 20  720  704 HOH HOH B . 
N 5 HOH 21  721  155 HOH HOH B . 
N 5 HOH 22  722  637 HOH HOH B . 
N 5 HOH 23  723  578 HOH HOH B . 
N 5 HOH 24  724  402 HOH HOH B . 
N 5 HOH 25  725  195 HOH HOH B . 
N 5 HOH 26  726  767 HOH HOH B . 
N 5 HOH 27  727  21  HOH HOH B . 
N 5 HOH 28  728  208 HOH HOH B . 
N 5 HOH 29  729  852 HOH HOH B . 
N 5 HOH 30  730  321 HOH HOH B . 
N 5 HOH 31  731  419 HOH HOH B . 
N 5 HOH 32  732  881 HOH HOH B . 
N 5 HOH 33  733  251 HOH HOH B . 
N 5 HOH 34  734  126 HOH HOH B . 
N 5 HOH 35  735  252 HOH HOH B . 
N 5 HOH 36  736  678 HOH HOH B . 
N 5 HOH 37  737  455 HOH HOH B . 
N 5 HOH 38  738  690 HOH HOH B . 
N 5 HOH 39  739  146 HOH HOH B . 
N 5 HOH 40  740  11  HOH HOH B . 
N 5 HOH 41  741  733 HOH HOH B . 
N 5 HOH 42  742  243 HOH HOH B . 
N 5 HOH 43  743  567 HOH HOH B . 
N 5 HOH 44  744  106 HOH HOH B . 
N 5 HOH 45  745  597 HOH HOH B . 
N 5 HOH 46  746  558 HOH HOH B . 
N 5 HOH 47  747  454 HOH HOH B . 
N 5 HOH 48  748  676 HOH HOH B . 
N 5 HOH 49  749  291 HOH HOH B . 
N 5 HOH 50  750  143 HOH HOH B . 
N 5 HOH 51  751  382 HOH HOH B . 
N 5 HOH 52  752  697 HOH HOH B . 
N 5 HOH 53  753  160 HOH HOH B . 
N 5 HOH 54  754  35  HOH HOH B . 
N 5 HOH 55  755  846 HOH HOH B . 
N 5 HOH 56  756  634 HOH HOH B . 
N 5 HOH 57  757  353 HOH HOH B . 
N 5 HOH 58  758  97  HOH HOH B . 
N 5 HOH 59  759  55  HOH HOH B . 
N 5 HOH 60  760  408 HOH HOH B . 
N 5 HOH 61  761  70  HOH HOH B . 
N 5 HOH 62  762  174 HOH HOH B . 
N 5 HOH 63  763  235 HOH HOH B . 
N 5 HOH 64  764  200 HOH HOH B . 
N 5 HOH 65  765  500 HOH HOH B . 
N 5 HOH 66  766  92  HOH HOH B . 
N 5 HOH 67  767  288 HOH HOH B . 
N 5 HOH 68  768  452 HOH HOH B . 
N 5 HOH 69  769  247 HOH HOH B . 
N 5 HOH 70  770  605 HOH HOH B . 
N 5 HOH 71  771  109 HOH HOH B . 
N 5 HOH 72  772  365 HOH HOH B . 
N 5 HOH 73  773  426 HOH HOH B . 
N 5 HOH 74  774  14  HOH HOH B . 
N 5 HOH 75  775  703 HOH HOH B . 
N 5 HOH 76  776  587 HOH HOH B . 
N 5 HOH 77  777  509 HOH HOH B . 
N 5 HOH 78  778  292 HOH HOH B . 
N 5 HOH 79  779  220 HOH HOH B . 
N 5 HOH 80  780  749 HOH HOH B . 
N 5 HOH 81  781  474 HOH HOH B . 
N 5 HOH 82  782  20  HOH HOH B . 
N 5 HOH 83  783  350 HOH HOH B . 
N 5 HOH 84  784  488 HOH HOH B . 
N 5 HOH 85  785  536 HOH HOH B . 
N 5 HOH 86  786  646 HOH HOH B . 
N 5 HOH 87  787  172 HOH HOH B . 
N 5 HOH 88  788  354 HOH HOH B . 
N 5 HOH 89  789  361 HOH HOH B . 
N 5 HOH 90  790  3   HOH HOH B . 
N 5 HOH 91  791  621 HOH HOH B . 
N 5 HOH 92  792  87  HOH HOH B . 
N 5 HOH 93  793  101 HOH HOH B . 
N 5 HOH 94  794  159 HOH HOH B . 
N 5 HOH 95  795  54  HOH HOH B . 
N 5 HOH 96  796  423 HOH HOH B . 
N 5 HOH 97  797  74  HOH HOH B . 
N 5 HOH 98  798  647 HOH HOH B . 
N 5 HOH 99  799  757 HOH HOH B . 
N 5 HOH 100 800  748 HOH HOH B . 
N 5 HOH 101 801  24  HOH HOH B . 
N 5 HOH 102 802  684 HOH HOH B . 
N 5 HOH 103 803  100 HOH HOH B . 
N 5 HOH 104 804  276 HOH HOH B . 
N 5 HOH 105 805  682 HOH HOH B . 
N 5 HOH 106 806  696 HOH HOH B . 
N 5 HOH 107 807  651 HOH HOH B . 
N 5 HOH 108 808  437 HOH HOH B . 
N 5 HOH 109 809  32  HOH HOH B . 
N 5 HOH 110 810  791 HOH HOH B . 
N 5 HOH 111 811  842 HOH HOH B . 
N 5 HOH 112 812  662 HOH HOH B . 
N 5 HOH 113 813  445 HOH HOH B . 
N 5 HOH 114 814  712 HOH HOH B . 
N 5 HOH 115 815  93  HOH HOH B . 
N 5 HOH 116 816  58  HOH HOH B . 
N 5 HOH 117 817  422 HOH HOH B . 
N 5 HOH 118 818  241 HOH HOH B . 
N 5 HOH 119 819  706 HOH HOH B . 
N 5 HOH 120 820  230 HOH HOH B . 
N 5 HOH 121 821  887 HOH HOH B . 
N 5 HOH 122 822  168 HOH HOH B . 
N 5 HOH 123 823  483 HOH HOH B . 
N 5 HOH 124 824  858 HOH HOH B . 
N 5 HOH 125 825  481 HOH HOH B . 
N 5 HOH 126 826  873 HOH HOH B . 
N 5 HOH 127 827  49  HOH HOH B . 
N 5 HOH 128 828  878 HOH HOH B . 
N 5 HOH 129 829  867 HOH HOH B . 
N 5 HOH 130 830  507 HOH HOH B . 
N 5 HOH 131 831  859 HOH HOH B . 
N 5 HOH 132 832  8   HOH HOH B . 
N 5 HOH 133 833  121 HOH HOH B . 
N 5 HOH 134 834  320 HOH HOH B . 
N 5 HOH 135 835  118 HOH HOH B . 
N 5 HOH 136 836  529 HOH HOH B . 
N 5 HOH 137 837  311 HOH HOH B . 
N 5 HOH 138 838  705 HOH HOH B . 
N 5 HOH 139 839  207 HOH HOH B . 
N 5 HOH 140 840  551 HOH HOH B . 
N 5 HOH 141 841  653 HOH HOH B . 
N 5 HOH 142 842  29  HOH HOH B . 
N 5 HOH 143 843  108 HOH HOH B . 
N 5 HOH 144 844  860 HOH HOH B . 
N 5 HOH 145 845  643 HOH HOH B . 
N 5 HOH 146 846  120 HOH HOH B . 
N 5 HOH 147 847  735 HOH HOH B . 
N 5 HOH 148 848  63  HOH HOH B . 
N 5 HOH 149 849  726 HOH HOH B . 
N 5 HOH 150 850  62  HOH HOH B . 
N 5 HOH 151 851  356 HOH HOH B . 
N 5 HOH 152 852  561 HOH HOH B . 
N 5 HOH 153 853  530 HOH HOH B . 
N 5 HOH 154 854  148 HOH HOH B . 
N 5 HOH 155 855  414 HOH HOH B . 
N 5 HOH 156 856  36  HOH HOH B . 
N 5 HOH 157 857  783 HOH HOH B . 
N 5 HOH 158 858  372 HOH HOH B . 
N 5 HOH 159 859  137 HOH HOH B . 
N 5 HOH 160 860  4   HOH HOH B . 
N 5 HOH 161 861  218 HOH HOH B . 
N 5 HOH 162 862  165 HOH HOH B . 
N 5 HOH 163 863  102 HOH HOH B . 
N 5 HOH 164 864  198 HOH HOH B . 
N 5 HOH 165 865  819 HOH HOH B . 
N 5 HOH 166 866  88  HOH HOH B . 
N 5 HOH 167 867  738 HOH HOH B . 
N 5 HOH 168 868  253 HOH HOH B . 
N 5 HOH 169 869  770 HOH HOH B . 
N 5 HOH 170 870  44  HOH HOH B . 
N 5 HOH 171 871  226 HOH HOH B . 
N 5 HOH 172 872  15  HOH HOH B . 
N 5 HOH 173 873  347 HOH HOH B . 
N 5 HOH 174 874  453 HOH HOH B . 
N 5 HOH 175 875  225 HOH HOH B . 
N 5 HOH 176 876  847 HOH HOH B . 
N 5 HOH 177 877  498 HOH HOH B . 
N 5 HOH 178 878  128 HOH HOH B . 
N 5 HOH 179 879  256 HOH HOH B . 
N 5 HOH 180 880  669 HOH HOH B . 
N 5 HOH 181 881  298 HOH HOH B . 
N 5 HOH 182 882  677 HOH HOH B . 
N 5 HOH 183 883  219 HOH HOH B . 
N 5 HOH 184 884  212 HOH HOH B . 
N 5 HOH 185 885  475 HOH HOH B . 
N 5 HOH 186 886  255 HOH HOH B . 
N 5 HOH 187 887  368 HOH HOH B . 
N 5 HOH 188 888  731 HOH HOH B . 
N 5 HOH 189 889  680 HOH HOH B . 
N 5 HOH 190 890  153 HOH HOH B . 
N 5 HOH 191 891  286 HOH HOH B . 
N 5 HOH 192 892  624 HOH HOH B . 
N 5 HOH 193 893  686 HOH HOH B . 
N 5 HOH 194 894  324 HOH HOH B . 
N 5 HOH 195 895  204 HOH HOH B . 
N 5 HOH 196 896  227 HOH HOH B . 
N 5 HOH 197 897  755 HOH HOH B . 
N 5 HOH 198 898  450 HOH HOH B . 
N 5 HOH 199 899  231 HOH HOH B . 
N 5 HOH 200 900  167 HOH HOH B . 
N 5 HOH 201 901  299 HOH HOH B . 
N 5 HOH 202 902  179 HOH HOH B . 
N 5 HOH 203 903  523 HOH HOH B . 
N 5 HOH 204 904  632 HOH HOH B . 
N 5 HOH 205 905  333 HOH HOH B . 
N 5 HOH 206 906  145 HOH HOH B . 
N 5 HOH 207 907  539 HOH HOH B . 
N 5 HOH 208 908  12  HOH HOH B . 
N 5 HOH 209 909  184 HOH HOH B . 
N 5 HOH 210 910  584 HOH HOH B . 
N 5 HOH 211 911  857 HOH HOH B . 
N 5 HOH 212 912  41  HOH HOH B . 
N 5 HOH 213 913  190 HOH HOH B . 
N 5 HOH 214 914  111 HOH HOH B . 
N 5 HOH 215 915  701 HOH HOH B . 
N 5 HOH 216 916  540 HOH HOH B . 
N 5 HOH 217 917  816 HOH HOH B . 
N 5 HOH 218 918  239 HOH HOH B . 
N 5 HOH 219 919  83  HOH HOH B . 
N 5 HOH 220 920  792 HOH HOH B . 
N 5 HOH 221 921  537 HOH HOH B . 
N 5 HOH 222 922  171 HOH HOH B . 
N 5 HOH 223 923  182 HOH HOH B . 
N 5 HOH 224 924  877 HOH HOH B . 
N 5 HOH 225 925  223 HOH HOH B . 
N 5 HOH 226 926  259 HOH HOH B . 
N 5 HOH 227 927  222 HOH HOH B . 
N 5 HOH 228 928  759 HOH HOH B . 
N 5 HOH 229 929  266 HOH HOH B . 
N 5 HOH 230 930  505 HOH HOH B . 
N 5 HOH 231 931  484 HOH HOH B . 
N 5 HOH 232 932  245 HOH HOH B . 
N 5 HOH 233 933  157 HOH HOH B . 
N 5 HOH 234 934  258 HOH HOH B . 
N 5 HOH 235 935  76  HOH HOH B . 
N 5 HOH 236 936  838 HOH HOH B . 
N 5 HOH 237 937  548 HOH HOH B . 
N 5 HOH 238 938  845 HOH HOH B . 
N 5 HOH 239 939  51  HOH HOH B . 
N 5 HOH 240 940  91  HOH HOH B . 
N 5 HOH 241 941  31  HOH HOH B . 
N 5 HOH 242 942  841 HOH HOH B . 
N 5 HOH 243 943  751 HOH HOH B . 
N 5 HOH 244 944  818 HOH HOH B . 
N 5 HOH 245 945  609 HOH HOH B . 
N 5 HOH 246 946  853 HOH HOH B . 
N 5 HOH 247 947  839 HOH HOH B . 
N 5 HOH 248 948  502 HOH HOH B . 
N 5 HOH 249 949  346 HOH HOH B . 
N 5 HOH 250 950  746 HOH HOH B . 
N 5 HOH 251 951  820 HOH HOH B . 
N 5 HOH 252 952  216 HOH HOH B . 
N 5 HOH 253 953  553 HOH HOH B . 
N 5 HOH 254 954  386 HOH HOH B . 
N 5 HOH 255 955  181 HOH HOH B . 
N 5 HOH 256 956  405 HOH HOH B . 
N 5 HOH 257 957  762 HOH HOH B . 
N 5 HOH 258 958  683 HOH HOH B . 
N 5 HOH 259 959  289 HOH HOH B . 
N 5 HOH 260 960  119 HOH HOH B . 
N 5 HOH 261 961  214 HOH HOH B . 
N 5 HOH 262 962  415 HOH HOH B . 
N 5 HOH 263 963  837 HOH HOH B . 
N 5 HOH 264 964  364 HOH HOH B . 
N 5 HOH 265 965  392 HOH HOH B . 
N 5 HOH 266 966  318 HOH HOH B . 
N 5 HOH 267 967  444 HOH HOH B . 
N 5 HOH 268 968  499 HOH HOH B . 
N 5 HOH 269 969  104 HOH HOH B . 
N 5 HOH 270 970  728 HOH HOH B . 
N 5 HOH 271 971  98  HOH HOH B . 
N 5 HOH 272 972  525 HOH HOH B . 
N 5 HOH 273 973  469 HOH HOH B . 
N 5 HOH 274 974  670 HOH HOH B . 
N 5 HOH 275 975  79  HOH HOH B . 
N 5 HOH 276 976  334 HOH HOH B . 
N 5 HOH 277 977  699 HOH HOH B . 
N 5 HOH 278 978  814 HOH HOH B . 
N 5 HOH 279 979  719 HOH HOH B . 
N 5 HOH 280 980  513 HOH HOH B . 
N 5 HOH 281 981  90  HOH HOH B . 
N 5 HOH 282 982  631 HOH HOH B . 
N 5 HOH 283 983  78  HOH HOH B . 
N 5 HOH 284 984  342 HOH HOH B . 
N 5 HOH 285 985  543 HOH HOH B . 
N 5 HOH 286 986  556 HOH HOH B . 
N 5 HOH 287 987  127 HOH HOH B . 
N 5 HOH 288 988  30  HOH HOH B . 
N 5 HOH 289 989  458 HOH HOH B . 
N 5 HOH 290 990  355 HOH HOH B . 
N 5 HOH 291 991  879 HOH HOH B . 
N 5 HOH 292 992  384 HOH HOH B . 
N 5 HOH 293 993  861 HOH HOH B . 
N 5 HOH 294 994  240 HOH HOH B . 
N 5 HOH 295 995  52  HOH HOH B . 
N 5 HOH 296 996  599 HOH HOH B . 
N 5 HOH 297 997  566 HOH HOH B . 
N 5 HOH 298 998  589 HOH HOH B . 
N 5 HOH 299 999  138 HOH HOH B . 
N 5 HOH 300 1000 885 HOH HOH B . 
N 5 HOH 301 1001 254 HOH HOH B . 
N 5 HOH 302 1002 533 HOH HOH B . 
N 5 HOH 303 1003 763 HOH HOH B . 
N 5 HOH 304 1004 95  HOH HOH B . 
N 5 HOH 305 1005 689 HOH HOH B . 
N 5 HOH 306 1006 360 HOH HOH B . 
N 5 HOH 307 1007 234 HOH HOH B . 
N 5 HOH 308 1008 166 HOH HOH B . 
N 5 HOH 309 1009 623 HOH HOH B . 
N 5 HOH 310 1010 284 HOH HOH B . 
N 5 HOH 311 1011 724 HOH HOH B . 
N 5 HOH 312 1012 886 HOH HOH B . 
N 5 HOH 313 1013 709 HOH HOH B . 
N 5 HOH 314 1014 574 HOH HOH B . 
N 5 HOH 315 1015 736 HOH HOH B . 
N 5 HOH 316 1016 723 HOH HOH B . 
N 5 HOH 317 1017 377 HOH HOH B . 
N 5 HOH 318 1018 369 HOH HOH B . 
N 5 HOH 319 1019 744 HOH HOH B . 
N 5 HOH 320 1020 221 HOH HOH B . 
N 5 HOH 321 1021 337 HOH HOH B . 
N 5 HOH 322 1022 612 HOH HOH B . 
N 5 HOH 323 1023 249 HOH HOH B . 
N 5 HOH 324 1024 772 HOH HOH B . 
N 5 HOH 325 1025 60  HOH HOH B . 
N 5 HOH 326 1026 661 HOH HOH B . 
N 5 HOH 327 1027 332 HOH HOH B . 
N 5 HOH 328 1028 470 HOH HOH B . 
N 5 HOH 329 1029 512 HOH HOH B . 
N 5 HOH 330 1030 236 HOH HOH B . 
N 5 HOH 331 1031 209 HOH HOH B . 
N 5 HOH 332 1032 163 HOH HOH B . 
N 5 HOH 333 1033 880 HOH HOH B . 
N 5 HOH 334 1034 526 HOH HOH B . 
N 5 HOH 335 1035 641 HOH HOH B . 
N 5 HOH 336 1036 323 HOH HOH B . 
N 5 HOH 337 1037 616 HOH HOH B . 
N 5 HOH 338 1038 65  HOH HOH B . 
N 5 HOH 339 1039 13  HOH HOH B . 
N 5 HOH 340 1040 779 HOH HOH B . 
N 5 HOH 341 1041 564 HOH HOH B . 
N 5 HOH 342 1042 476 HOH HOH B . 
N 5 HOH 343 1043 335 HOH HOH B . 
N 5 HOH 344 1044 383 HOH HOH B . 
N 5 HOH 345 1045 164 HOH HOH B . 
N 5 HOH 346 1046 440 HOH HOH B . 
N 5 HOH 347 1047 863 HOH HOH B . 
N 5 HOH 348 1048 248 HOH HOH B . 
N 5 HOH 349 1049 765 HOH HOH B . 
N 5 HOH 350 1050 135 HOH HOH B . 
N 5 HOH 351 1051 741 HOH HOH B . 
N 5 HOH 352 1052 737 HOH HOH B . 
N 5 HOH 353 1053 375 HOH HOH B . 
N 5 HOH 354 1054 893 HOH HOH B . 
N 5 HOH 355 1055 80  HOH HOH B . 
N 5 HOH 356 1056 652 HOH HOH B . 
N 5 HOH 357 1057 69  HOH HOH B . 
N 5 HOH 358 1058 532 HOH HOH B . 
N 5 HOH 359 1059 716 HOH HOH B . 
N 5 HOH 360 1060 351 HOH HOH B . 
N 5 HOH 361 1061 312 HOH HOH B . 
N 5 HOH 362 1062 883 HOH HOH B . 
N 5 HOH 363 1063 517 HOH HOH B . 
N 5 HOH 364 1064 362 HOH HOH B . 
N 5 HOH 365 1065 598 HOH HOH B . 
N 5 HOH 366 1066 626 HOH HOH B . 
N 5 HOH 367 1067 96  HOH HOH B . 
N 5 HOH 368 1068 112 HOH HOH B . 
N 5 HOH 369 1069 585 HOH HOH B . 
N 5 HOH 370 1070 57  HOH HOH B . 
N 5 HOH 371 1071 650 HOH HOH B . 
N 5 HOH 372 1072 515 HOH HOH B . 
N 5 HOH 373 1073 233 HOH HOH B . 
N 5 HOH 374 1074 471 HOH HOH B . 
N 5 HOH 375 1075 645 HOH HOH B . 
N 5 HOH 376 1076 449 HOH HOH B . 
N 5 HOH 377 1077 648 HOH HOH B . 
N 5 HOH 378 1078 700 HOH HOH B . 
N 5 HOH 379 1079 595 HOH HOH B . 
N 5 HOH 380 1080 563 HOH HOH B . 
N 5 HOH 381 1081 246 HOH HOH B . 
N 5 HOH 382 1082 431 HOH HOH B . 
N 5 HOH 383 1083 5   HOH HOH B . 
N 5 HOH 384 1084 308 HOH HOH B . 
N 5 HOH 385 1085 416 HOH HOH B . 
N 5 HOH 386 1086 658 HOH HOH B . 
N 5 HOH 387 1087 524 HOH HOH B . 
N 5 HOH 388 1088 640 HOH HOH B . 
N 5 HOH 389 1089 777 HOH HOH B . 
N 5 HOH 390 1090 122 HOH HOH B . 
N 5 HOH 391 1091 319 HOH HOH B . 
N 5 HOH 392 1092 477 HOH HOH B . 
N 5 HOH 393 1093 411 HOH HOH B . 
N 5 HOH 394 1094 797 HOH HOH B . 
N 5 HOH 395 1095 47  HOH HOH B . 
N 5 HOH 396 1096 373 HOH HOH B . 
N 5 HOH 397 1097 583 HOH HOH B . 
N 5 HOH 398 1098 729 HOH HOH B . 
N 5 HOH 399 1099 401 HOH HOH B . 
N 5 HOH 400 1100 781 HOH HOH B . 
N 5 HOH 401 1101 828 HOH HOH B . 
N 5 HOH 402 1102 345 HOH HOH B . 
N 5 HOH 403 1103 586 HOH HOH B . 
N 5 HOH 404 1104 668 HOH HOH B . 
N 5 HOH 405 1105 826 HOH HOH B . 
N 5 HOH 406 1106 381 HOH HOH B . 
N 5 HOH 407 1107 494 HOH HOH B . 
N 5 HOH 408 1108 891 HOH HOH B . 
N 5 HOH 409 1109 747 HOH HOH B . 
N 5 HOH 410 1110 527 HOH HOH B . 
N 5 HOH 411 1111 758 HOH HOH B . 
N 5 HOH 412 1112 780 HOH HOH B . 
N 5 HOH 413 1113 707 HOH HOH B . 
N 5 HOH 414 1114 180 HOH HOH B . 
N 5 HOH 415 1115 514 HOH HOH B . 
N 5 HOH 416 1116 591 HOH HOH B . 
N 5 HOH 417 1117 756 HOH HOH B . 
N 5 HOH 418 1118 555 HOH HOH B . 
N 5 HOH 419 1119 785 HOH HOH B . 
N 5 HOH 420 1120 317 HOH HOH B . 
N 5 HOH 421 1121 604 HOH HOH B . 
N 5 HOH 422 1122 776 HOH HOH B . 
N 5 HOH 423 1123 541 HOH HOH B . 
N 5 HOH 424 1124 815 HOH HOH B . 
N 5 HOH 425 1125 302 HOH HOH B . 
N 5 HOH 426 1126 576 HOH HOH B . 
N 5 HOH 427 1127 601 HOH HOH B . 
N 5 HOH 428 1128 430 HOH HOH B . 
N 5 HOH 429 1129 771 HOH HOH B . 
N 5 HOH 430 1130 387 HOH HOH B . 
N 5 HOH 431 1131 636 HOH HOH B . 
N 5 HOH 432 1132 808 HOH HOH B . 
N 5 HOH 433 1133 671 HOH HOH B . 
N 5 HOH 434 1134 872 HOH HOH B . 
N 5 HOH 435 1135 531 HOH HOH B . 
N 5 HOH 436 1136 809 HOH HOH B . 
N 5 HOH 437 1137 799 HOH HOH B . 
N 5 HOH 438 1138 802 HOH HOH B . 
N 5 HOH 439 1139 456 HOH HOH B . 
N 5 HOH 440 1140 273 HOH HOH B . 
N 5 HOH 441 1141 630 HOH HOH B . 
N 5 HOH 442 1142 642 HOH HOH B . 
N 5 HOH 443 1143 811 HOH HOH B . 
N 5 HOH 444 1144 830 HOH HOH B . 
N 5 HOH 445 1145 614 HOH HOH B . 
N 5 HOH 446 1146 492 HOH HOH B . 
N 5 HOH 447 1147 786 HOH HOH B . 
N 5 HOH 448 1148 774 HOH HOH B . 
N 5 HOH 449 1149 290 HOH HOH B . 
N 5 HOH 450 1150 439 HOH HOH B . 
N 5 HOH 451 1151 754 HOH HOH B . 
N 5 HOH 452 1152 279 HOH HOH B . 
N 5 HOH 453 1153 798 HOH HOH B . 
N 5 HOH 454 1154 307 HOH HOH B . 
N 5 HOH 455 1155 446 HOH HOH B . 
N 5 HOH 456 1156 813 HOH HOH B . 
N 5 HOH 457 1157 824 HOH HOH B . 
N 5 HOH 458 1158 501 HOH HOH B . 
N 5 HOH 459 1159 413 HOH HOH B . 
N 5 HOH 460 1160 810 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A TYR 24 ? CG  ? A TYR 32 CG  
2  1 Y 1 A TYR 24 ? CD1 ? A TYR 32 CD1 
3  1 Y 1 A TYR 24 ? CD2 ? A TYR 32 CD2 
4  1 Y 1 A TYR 24 ? CE1 ? A TYR 32 CE1 
5  1 Y 1 A TYR 24 ? CE2 ? A TYR 32 CE2 
6  1 Y 1 A TYR 24 ? CZ  ? A TYR 32 CZ  
7  1 Y 1 A TYR 24 ? OH  ? A TYR 32 OH  
8  1 Y 1 B TYR 24 ? CG  ? B TYR 32 CG  
9  1 Y 1 B TYR 24 ? CD1 ? B TYR 32 CD1 
10 1 Y 1 B TYR 24 ? CD2 ? B TYR 32 CD2 
11 1 Y 1 B TYR 24 ? CE1 ? B TYR 32 CE1 
12 1 Y 1 B TYR 24 ? CE2 ? B TYR 32 CE2 
13 1 Y 1 B TYR 24 ? CZ  ? B TYR 32 CZ  
14 1 Y 1 B TYR 24 ? OH  ? B TYR 32 OH  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0430 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   108.349 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9G89 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     71.68 
_cell.length_a_esd                 ? 
_cell.length_b                     84.676 
_cell.length_b_esd                 ? 
_cell.length_c                     106.571 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9G89 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9G89 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.44 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.59 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1MPCTP 7.0 25% w/v PEG 1500 30% GOL' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-18 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03322 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03322 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9G89 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.67 
_reflns.d_resolution_low                               48.56 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     137992 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.01 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.103 
_reflns.pdbx_Rpim_I_all                                0.054 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.087 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
9.15 48.56 ? 47.1 ? ? ? ? 892  ? ? ? ? ? ? ? ? ? ? ? 6.7 1.06 ? ? 0.039 0.020 ? 1 ? 0.999 ? ? 99.0 ? 0.033 ? ? ? ? ? ? ? ? ? 
1.67 1.70  ? 1.2  ? ? ? ? 6796 ? ? ? ? ? ? ? ? ? ? ? 7.0 0.96 ? ? 1.737 0.911 ? 2 ? 0.528 ? ? 98.4 ? 1.473 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -0.636 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            0.811 
_refine.aniso_B[2][2]                            0.514 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -0.342 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               26.999 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.974 
_refine.correlation_coeff_Fo_to_Fc_free          0.961 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9G89 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.671 
_refine.ls_d_res_low                             48.56 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     137923 
_refine.ls_number_reflns_R_free                  6946 
_refine.ls_number_reflns_R_work                  130977 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.667 
_refine.ls_percent_reflns_R_free                 5.036 
_refine.ls_R_factor_all                          0.164 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1944 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1629 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.088 
_refine.pdbx_overall_ESU_R_Free                  0.089 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             2.235 
_refine.overall_SU_ML                            0.070 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.671 
_refine_hist.d_res_low                        48.56 
_refine_hist.number_atoms_solvent             893 
_refine_hist.number_atoms_total               9359 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8406 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         60 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  8733  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.919  1.820  11877 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.502  5.000  1050  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 8.176  6.000  60    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 12.521 10.000 1357  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.962 10.000 429   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.124  0.200  1223  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.011  0.020  6977  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200  4250  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.306  0.200  5922  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.146  0.200  957   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  65    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.324  0.200  23    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.266  2.430  4203  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.010  4.357  5252  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.530  2.690  4530  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.877  4.792  6625  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.765  28.511 14062 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 0.062  0.050  17841 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.06152 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.06152 ? 0.05009 2 'Local ncs' ? B ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.671 1.715 10277 . 534 9599 98.5988 . 0.286 . . 0.285 . . . . . 0.275 . 20 . 0.939 0.935 0.303 
'X-RAY DIFFRACTION' 1.715 1.761 10015 . 467 9465 99.1712 . 0.271 . . 0.269 . . . . . 0.254 . 20 . 0.948 0.937 0.298 
'X-RAY DIFFRACTION' 1.761 1.812 9772  . 506 9133 98.6390 . 0.245 . . 0.244 . . . . . 0.225 . 20 . 0.959 0.947 0.276 
'X-RAY DIFFRACTION' 1.812 1.868 9460  . 438 8762 97.2516 . 0.227 . . 0.225 . . . . . 0.201 . 20 . 0.965 0.957 0.260 
'X-RAY DIFFRACTION' 1.868 1.929 9203  . 427 8554 97.5877 . 0.201 . . 0.200 . . . . . 0.175 . 20 . 0.974 0.968 0.218 
'X-RAY DIFFRACTION' 1.929 1.997 8885  . 396 8423 99.2572 . 0.181 . . 0.179 . . . . . 0.157 . 20 . 0.980 0.972 0.214 
'X-RAY DIFFRACTION' 1.997 2.072 8562  . 456 8039 99.2175 . 0.168 . . 0.167 . . . . . 0.144 . 20 . 0.983 0.976 0.197 
'X-RAY DIFFRACTION' 2.072 2.157 8245  . 435 7771 99.5270 . 0.162 . . 0.161 . . . . . 0.140 . 20 . 0.984 0.978 0.186 
'X-RAY DIFFRACTION' 2.157 2.252 7974  . 435 7495 99.4482 . 0.159 . . 0.157 . . . . . 0.135 . 20 . 0.985 0.977 0.192 
'X-RAY DIFFRACTION' 2.252 2.362 7600  . 384 7159 99.2500 . 0.152 . . 0.150 . . . . . 0.129 . 20 . 0.986 0.978 0.191 
'X-RAY DIFFRACTION' 2.362 2.489 7212  . 365 6764 98.8491 . 0.164 . . 0.161 . . . . . 0.140 . 20 . 0.984 0.971 0.220 
'X-RAY DIFFRACTION' 2.489 2.640 6850  . 312 6301 96.5401 . 0.170 . . 0.168 . . . . . 0.147 . 20 . 0.984 0.974 0.213 
'X-RAY DIFFRACTION' 2.640 2.822 6402  . 320 5991 98.5786 . 0.155 . . 0.153 . . . . . 0.137 . 20 . 0.986 0.978 0.193 
'X-RAY DIFFRACTION' 2.822 3.047 5984  . 303 5637 99.2647 . 0.155 . . 0.153 . . . . . 0.140 . 20 . 0.986 0.981 0.180 
'X-RAY DIFFRACTION' 3.047 3.336 5511  . 277 5188 99.1653 . 0.151 . . 0.150 . . . . . 0.142 . 20 . 0.986 0.981 0.175 
'X-RAY DIFFRACTION' 3.336 3.728 5021  . 262 4721 99.2432 . 0.148 . . 0.147 . . . . . 0.145 . 20 . 0.987 0.983 0.167 
'X-RAY DIFFRACTION' 3.728 4.300 4418  . 196 4195 99.3889 . 0.133 . . 0.132 . . . . . 0.137 . 20 . 0.990 0.984 0.169 
'X-RAY DIFFRACTION' 4.300 5.257 3761  . 198 3393 95.4799 . 0.132 . . 0.130 . . . . . 0.140 . 20 . 0.991 0.986 0.168 
'X-RAY DIFFRACTION' 5.257 7.391 2936  . 152 2783 99.9659 . 0.157 . . 0.156 . . . . . 0.164 . 20 . 0.987 0.983 0.183 
'X-RAY DIFFRACTION' 7.391 48.56 1690  . 83  1604 99.8225 . 0.153 . . 0.152 . . . . . 0.164 . 20 . 0.987 0.983 0.163 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 B 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A TYR 32 . A ALA 556 . A TYR 24 A ALA 548 ? ? 
1 2 1 B TYR 32 . B ALA 556 . B TYR 24 B ALA 548 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9G89 
_struct.title                        'Carotenoid cleavage oxygenase from Moesziomyces aphidis bound to vanillin' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9G89 
_struct_keywords.text            'oxygenase, Moesziomyces aphidis, vanillin, METAL BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'METAL BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 4 ? 
J N N 2 ? 
K N N 3 ? 
L N N 4 ? 
M N N 5 ? 
N N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    W3VHW6_MOEAP 
_struct_ref.pdbx_db_accession          W3VHW6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFYRIMPDYAQP
PTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVESTANTNVVMH
AGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDPSGKVVRDLW
LEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNGMPIHTASGF
EDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEFPQIDNRFMG
VEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLAIVDRLDLNR
SEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9G89 A 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
2 1 9G89 B 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9G89 MET A 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 1  
1 9G89 TRP A 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 2  
1 9G89 SER A 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 3  
1 9G89 HIS A 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 4  
1 9G89 PRO A 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 5  
1 9G89 GLN A 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 6  
1 9G89 PHE A 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 7  
1 9G89 GLU A 8 ? UNP W3VHW6 ? ? 'expression tag'        0  8  
1 9G89 LYS A 9 ? UNP W3VHW6 ? ? 'expression tag'        1  9  
2 9G89 MET B 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 10 
2 9G89 TRP B 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 11 
2 9G89 SER B 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 12 
2 9G89 HIS B 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 13 
2 9G89 PRO B 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 14 
2 9G89 GLN B 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 15 
2 9G89 PHE B 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 16 
2 9G89 GLU B 8 ? UNP W3VHW6 ? ? 'expression tag'        0  17 
2 9G89 LYS B 9 ? UNP W3VHW6 ? ? 'expression tag'        1  18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,F,G,H,I,M 
2 1 B,J,K,L,N         
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 34  ? LEU A 39  ? HIS A 26  LEU A 31  5 ? 6  
HELX_P HELX_P2  AA2 TYR A 93  ? GLU A 97  ? TYR A 85  GLU A 89  5 ? 5  
HELX_P HELX_P3  AA3 THR A 127 ? ARG A 137 ? THR A 119 ARG A 129 1 ? 11 
HELX_P HELX_P4  AA4 ASN A 146 ? HIS A 150 ? ASN A 138 HIS A 142 5 ? 5  
HELX_P HELX_P5  AA5 HIS A 151 ? ARG A 155 ? HIS A 143 ARG A 147 5 ? 5  
HELX_P HELX_P6  AA6 ASN A 278 ? ALA A 284 ? ASN A 270 ALA A 276 1 ? 7  
HELX_P HELX_P7  AA7 SER A 308 ? VAL A 312 ? SER A 300 VAL A 304 5 ? 5  
HELX_P HELX_P8  AA8 SER A 355 ? GLY A 366 ? SER A 347 GLY A 358 1 ? 12 
HELX_P HELX_P9  AA9 ASN A 405 ? MET A 408 ? ASN A 397 MET A 400 5 ? 4  
HELX_P HELX_P10 AB1 ARG A 498 ? PHE A 500 ? ARG A 490 PHE A 492 5 ? 3  
HELX_P HELX_P11 AB2 GLU A 525 ? THR A 527 ? GLU A 517 THR A 519 5 ? 3  
HELX_P HELX_P12 AB3 PRO A 546 ? SER A 550 ? PRO A 538 SER A 542 5 ? 5  
HELX_P HELX_P13 AB4 HIS B 34  ? LEU B 39  ? HIS B 26  LEU B 31  5 ? 6  
HELX_P HELX_P14 AB5 TYR B 93  ? GLU B 97  ? TYR B 85  GLU B 89  5 ? 5  
HELX_P HELX_P15 AB6 THR B 127 ? ARG B 137 ? THR B 119 ARG B 129 1 ? 11 
HELX_P HELX_P16 AB7 ASN B 146 ? HIS B 150 ? ASN B 138 HIS B 142 5 ? 5  
HELX_P HELX_P17 AB8 HIS B 151 ? ARG B 155 ? HIS B 143 ARG B 147 5 ? 5  
HELX_P HELX_P18 AB9 ASN B 278 ? ALA B 284 ? ASN B 270 ALA B 276 1 ? 7  
HELX_P HELX_P19 AC1 SER B 308 ? VAL B 312 ? SER B 300 VAL B 304 5 ? 5  
HELX_P HELX_P20 AC2 SER B 355 ? GLY B 366 ? SER B 347 GLY B 358 1 ? 12 
HELX_P HELX_P21 AC3 ASN B 405 ? MET B 408 ? ASN B 397 MET B 400 5 ? 4  
HELX_P HELX_P22 AC4 ARG B 498 ? PHE B 500 ? ARG B 490 PHE B 492 5 ? 3  
HELX_P HELX_P23 AC5 GLU B 525 ? THR B 527 ? GLU B 517 THR B 519 5 ? 3  
HELX_P HELX_P24 AC6 PRO B 546 ? SER B 550 ? PRO B 538 SER B 542 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS 208 NE2 ? ? ? 1_555 I FE2 . FE ? ? A HIS 200 A FE2 607 1_555 ? ? ? ? ? ? ? 2.149 ? ? 
metalc2  metalc ? ? A HIS 259 NE2 ? ? ? 1_555 I FE2 . FE ? ? A HIS 251 A FE2 607 1_555 ? ? ? ? ? ? ? 2.112 ? ? 
metalc3  metalc ? ? A HIS 324 NE2 ? ? ? 1_555 I FE2 . FE ? ? A HIS 316 A FE2 607 1_555 ? ? ? ? ? ? ? 2.136 ? ? 
metalc4  metalc ? ? A HIS 518 NE2 ? ? ? 1_555 I FE2 . FE ? ? A HIS 510 A FE2 607 1_555 ? ? ? ? ? ? ? 2.158 ? ? 
metalc5  metalc ? ? I FE2 .   FE  ? ? ? 1_555 M HOH . O  ? ? A FE2 607 A HOH 704 1_555 ? ? ? ? ? ? ? 2.004 ? ? 
metalc6  metalc ? ? B HIS 208 NE2 ? ? ? 1_555 L FE2 . FE ? ? B HIS 200 B FE2 603 1_555 ? ? ? ? ? ? ? 2.179 ? ? 
metalc7  metalc ? ? B HIS 259 NE2 ? ? ? 1_555 L FE2 . FE ? ? B HIS 251 B FE2 603 1_555 ? ? ? ? ? ? ? 2.117 ? ? 
metalc8  metalc ? ? B HIS 324 NE2 ? ? ? 1_555 L FE2 . FE ? ? B HIS 316 B FE2 603 1_555 ? ? ? ? ? ? ? 2.143 ? ? 
metalc9  metalc ? ? B HIS 518 NE2 ? ? ? 1_555 L FE2 . FE ? ? B HIS 510 B FE2 603 1_555 ? ? ? ? ? ? ? 2.145 ? ? 
metalc10 metalc ? ? L FE2 .   FE  ? ? ? 1_555 N HOH . O  ? ? B FE2 603 B HOH 702 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 259 ? A HIS 251 ? 1_555 93.8  ? 
2  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 102.8 ? 
3  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 96.8  ? 
4  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 89.5  ? 
5  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 172.8 ? 
6  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 88.7  ? 
7  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 O   ? M HOH .   ? A HOH 704 ? 1_555 151.1 ? 
8  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 O   ? M HOH .   ? A HOH 704 ? 1_555 87.0  ? 
9  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 O   ? M HOH .   ? A HOH 704 ? 1_555 105.8 ? 
10 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 FE ? I FE2 . ? A FE2 607 ? 1_555 O   ? M HOH .   ? A HOH 704 ? 1_555 87.1  ? 
11 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 93.1  ? 
12 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 102.3 ? 
13 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 97.3  ? 
14 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 88.3  ? 
15 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 172.3 ? 
16 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 89.8  ? 
17 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 O   ? N HOH .   ? B HOH 702 ? 1_555 155.2 ? 
18 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 O   ? N HOH .   ? B HOH 702 ? 1_555 87.5  ? 
19 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 O   ? N HOH .   ? B HOH 702 ? 1_555 102.2 ? 
20 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 FE ? L FE2 . ? B FE2 603 ? 1_555 O   ? N HOH .   ? B HOH 702 ? 1_555 88.0  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 5  ? 
AA3 ? 5  ? 
AA4 ? 4  ? 
AA5 ? 4  ? 
AA6 ? 3  ? 
AA7 ? 4  ? 
AA8 ? 4  ? 
AA9 ? 4  ? 
AB1 ? 5  ? 
AB2 ? 5  ? 
AB3 ? 4  ? 
AB4 ? 4  ? 
AB5 ? 3  ? 
AB6 ? 4  ? 
AB7 ? 4  ? 
AB8 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA1 4 5  ? anti-parallel 
AA1 5 6  ? anti-parallel 
AA1 6 7  ? anti-parallel 
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA3 3 4  ? anti-parallel 
AA3 4 5  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA5 2 3  ? anti-parallel 
AA5 3 4  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA6 2 3  ? anti-parallel 
AA7 1 2  ? anti-parallel 
AA7 2 3  ? anti-parallel 
AA7 3 4  ? anti-parallel 
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? anti-parallel 
AA9 3 4  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB1 4 5  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB2 4 5  ? anti-parallel 
AB3 1 2  ? anti-parallel 
AB3 2 3  ? anti-parallel 
AB3 3 4  ? anti-parallel 
AB4 1 2  ? anti-parallel 
AB4 2 3  ? anti-parallel 
AB4 3 4  ? anti-parallel 
AB5 1 2  ? anti-parallel 
AB5 2 3  ? anti-parallel 
AB6 1 2  ? anti-parallel 
AB6 2 3  ? anti-parallel 
AB6 3 4  ? anti-parallel 
AB7 1 2  ? anti-parallel 
AB7 2 3  ? anti-parallel 
AB7 3 4  ? anti-parallel 
AB8 1 2  ? anti-parallel 
AB8 2 3  ? anti-parallel 
AB8 3 4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLY A 519 ? PRO A 523 ? GLY A 511 PRO A 515 
AA1 2  GLY A 77  ? PRO A 84  ? GLY A 69  PRO A 76  
AA1 3  GLY A 106 ? LYS A 114 ? GLY A 98  LYS A 106 
AA1 4  LYS A 117 ? PHE A 124 ? LYS A 109 PHE A 116 
AA1 5  GLU A 59  ? ILE A 62  ? GLU A 51  ILE A 54  
AA1 6  GLU B 59  ? ILE B 62  ? GLU B 51  ILE B 54  
AA1 7  LYS B 117 ? PHE B 124 ? LYS B 109 PHE B 116 
AA1 8  GLY B 106 ? LYS B 114 ? GLY B 98  LYS B 106 
AA1 9  GLY B 77  ? PRO B 84  ? GLY B 69  PRO B 76  
AA1 10 GLY B 519 ? PRO B 523 ? GLY B 511 PRO B 515 
AA2 1  THR A 67  ? GLY A 69  ? THR A 59  GLY A 61  
AA2 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA2 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA2 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA2 5  CYS A 457 ? ILE A 459 ? CYS A 449 ILE A 451 
AA3 1  THR A 67  ? GLY A 69  ? THR A 59  GLY A 61  
AA3 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA3 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA3 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA3 5  VAL A 463 ? PRO A 466 ? VAL A 455 PRO A 458 
AA4 1  ASN A 165 ? HIS A 169 ? ASN A 157 HIS A 161 
AA4 2  ARG A 172 ? MET A 176 ? ARG A 164 MET A 168 
AA4 3  TYR A 183 ? MET A 185 ? TYR A 175 MET A 177 
AA4 4  THR A 192 ? TYR A 195 ? THR A 184 TYR A 187 
AA5 1  LYS A 210 ? GLN A 211 ? LYS A 202 GLN A 203 
AA5 2  LEU A 218 ? TYR A 223 ? LEU A 210 TYR A 215 
AA5 3  ASP A 232 ? VAL A 238 ? ASP A 224 VAL A 230 
AA5 4  VAL A 244 ? GLU A 251 ? VAL A 236 GLU A 243 
AA6 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA6 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA6 3  TRP A 289 ? TYR A 291 ? TRP A 281 TYR A 283 
AA7 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA7 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA7 3  THR A 298 ? PRO A 303 ? THR A 290 PRO A 295 
AA7 4  LYS A 313 ? HIS A 316 ? LYS A 305 HIS A 308 
AA8 1  THR A 325 ? GLU A 330 ? THR A 317 GLU A 322 
AA8 2  ILE A 336 ? VAL A 343 ? ILE A 328 VAL A 335 
AA8 3  ALA A 370 ? ILE A 377 ? ALA A 362 ILE A 369 
AA8 4  GLU A 391 ? LEU A 394 ? GLU A 383 LEU A 386 
AA9 1  SER A 398 ? ILE A 403 ? SER A 390 ILE A 395 
AA9 2  SER A 414 ? VAL A 419 ? SER A 406 VAL A 411 
AA9 3  GLY A 437 ? LYS A 442 ? GLY A 429 LYS A 434 
AA9 4  THR A 447 ? TYR A 452 ? THR A 439 TYR A 444 
AB1 1  THR B 67  ? GLY B 69  ? THR B 59  GLY B 61  
AB1 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB1 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB1 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB1 5  CYS B 457 ? ILE B 459 ? CYS B 449 ILE B 451 
AB2 1  THR B 67  ? GLY B 69  ? THR B 59  GLY B 61  
AB2 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB2 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB2 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB2 5  VAL B 463 ? PRO B 466 ? VAL B 455 PRO B 458 
AB3 1  ASN B 165 ? HIS B 169 ? ASN B 157 HIS B 161 
AB3 2  ARG B 172 ? MET B 176 ? ARG B 164 MET B 168 
AB3 3  TYR B 183 ? MET B 185 ? TYR B 175 MET B 177 
AB3 4  THR B 192 ? TYR B 195 ? THR B 184 TYR B 187 
AB4 1  LYS B 210 ? GLN B 211 ? LYS B 202 GLN B 203 
AB4 2  LEU B 218 ? TYR B 223 ? LEU B 210 TYR B 215 
AB4 3  ASP B 232 ? VAL B 238 ? ASP B 224 VAL B 230 
AB4 4  VAL B 244 ? GLU B 251 ? VAL B 236 GLU B 243 
AB5 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB5 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB5 3  TRP B 289 ? TYR B 291 ? TRP B 281 TYR B 283 
AB6 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB6 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB6 3  THR B 298 ? PRO B 303 ? THR B 290 PRO B 295 
AB6 4  LYS B 313 ? HIS B 316 ? LYS B 305 HIS B 308 
AB7 1  THR B 325 ? GLU B 330 ? THR B 317 GLU B 322 
AB7 2  ILE B 336 ? VAL B 343 ? ILE B 328 VAL B 335 
AB7 3  ALA B 370 ? ILE B 377 ? ALA B 362 ILE B 369 
AB7 4  GLU B 391 ? LEU B 394 ? GLU B 383 LEU B 386 
AB8 1  SER B 398 ? ILE B 403 ? SER B 390 ILE B 395 
AB8 2  SER B 414 ? VAL B 419 ? SER B 406 VAL B 411 
AB8 3  GLY B 437 ? LYS B 442 ? GLY B 429 LYS B 434 
AB8 4  THR B 447 ? TYR B 452 ? THR B 439 TYR B 444 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O ILE A 522 ? O ILE A 514 N THR A 78  ? N THR A 70  
AA1 2 3  N ARG A 81  ? N ARG A 73  O ALA A 109 ? O ALA A 101 
AA1 3 4  N ALA A 110 ? N ALA A 102 O ARG A 121 ? O ARG A 113 
AA1 4 5  O GLN A 122 ? O GLN A 114 N GLY A 60  ? N GLY A 52  
AA1 5 6  N GLU A 59  ? N GLU A 51  O THR B 61  ? O THR B 53  
AA1 6 7  N GLY B 60  ? N GLY B 52  O GLN B 122 ? O GLN B 114 
AA1 7 8  O ARG B 121 ? O ARG B 113 N ALA B 110 ? N ALA B 102 
AA1 8 9  O PHE B 113 ? O PHE B 105 N GLY B 77  ? N GLY B 69  
AA1 9 10 N THR B 78  ? N THR B 70  O ILE B 522 ? O ILE B 514 
AA2 1 2  N ARG A 68  ? N ARG A 60  O ALA A 506 ? O ALA A 498 
AA2 2 3  O VAL A 504 ? O VAL A 496 N VAL A 494 ? N VAL A 486 
AA2 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA2 4 5  O ASP A 483 ? O ASP A 475 N LEU A 458 ? N LEU A 450 
AA3 1 2  N ARG A 68  ? N ARG A 60  O ALA A 506 ? O ALA A 498 
AA3 2 3  O VAL A 504 ? O VAL A 496 N VAL A 494 ? N VAL A 486 
AA3 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA3 4 5  O PHE A 477 ? O PHE A 469 N SER A 465 ? N SER A 457 
AA4 1 2  N VAL A 167 ? N VAL A 159 O LEU A 174 ? O LEU A 166 
AA4 2 3  N ALA A 175 ? N ALA A 167 O TYR A 183 ? O TYR A 175 
AA4 3 4  N GLU A 184 ? N GLU A 176 O LEU A 193 ? O LEU A 185 
AA5 1 2  N LYS A 210 ? N LYS A 202 O VAL A 219 ? O VAL A 211 
AA5 2 3  N LEU A 218 ? N LEU A 210 O VAL A 238 ? O VAL A 230 
AA5 3 4  N TYR A 235 ? N TYR A 227 O LEU A 248 ? O LEU A 240 
AA6 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA6 2 3  N GLU A 276 ? N GLU A 268 O ALA A 290 ? O ALA A 282 
AA7 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA7 2 3  N LEU A 272 ? N LEU A 264 O THR A 298 ? O THR A 290 
AA7 3 4  N TRP A 299 ? N TRP A 291 O TRP A 315 ? O TRP A 307 
AA8 1 2  N PHE A 329 ? N PHE A 321 O ILE A 337 ? O ILE A 329 
AA8 2 3  N SER A 340 ? N SER A 332 O VAL A 373 ? O VAL A 365 
AA8 3 4  N PHE A 372 ? N PHE A 364 O ILE A 393 ? O ILE A 385 
AA9 1 2  N GLN A 402 ? N GLN A 394 O PHE A 416 ? O PHE A 408 
AA9 2 3  N ILE A 417 ? N ILE A 409 O ALA A 439 ? O ALA A 431 
AA9 3 4  N LEU A 438 ? N LEU A 430 O TYR A 451 ? O TYR A 443 
AB1 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB1 2 3  O VAL B 507 ? O VAL B 499 N VAL B 492 ? N VAL B 484 
AB1 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB1 4 5  O ASP B 483 ? O ASP B 475 N LEU B 458 ? N LEU B 450 
AB2 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB2 2 3  O VAL B 507 ? O VAL B 499 N VAL B 492 ? N VAL B 484 
AB2 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB2 4 5  O PHE B 477 ? O PHE B 469 N SER B 465 ? N SER B 457 
AB3 1 2  N VAL B 167 ? N VAL B 159 O LEU B 174 ? O LEU B 166 
AB3 2 3  N ALA B 175 ? N ALA B 167 O TYR B 183 ? O TYR B 175 
AB3 3 4  N GLU B 184 ? N GLU B 176 O LEU B 193 ? O LEU B 185 
AB4 1 2  N LYS B 210 ? N LYS B 202 O VAL B 219 ? O VAL B 211 
AB4 2 3  N LEU B 218 ? N LEU B 210 O VAL B 238 ? O VAL B 230 
AB4 3 4  N TYR B 235 ? N TYR B 227 O LEU B 248 ? O LEU B 240 
AB5 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB5 2 3  N GLU B 276 ? N GLU B 268 O ALA B 290 ? O ALA B 282 
AB6 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB6 2 3  N LEU B 272 ? N LEU B 264 O THR B 298 ? O THR B 290 
AB6 3 4  N TRP B 299 ? N TRP B 291 O TRP B 315 ? O TRP B 307 
AB7 1 2  N PHE B 329 ? N PHE B 321 O ILE B 337 ? O ILE B 329 
AB7 2 3  N ILE B 338 ? N ILE B 330 O TRP B 375 ? O TRP B 367 
AB7 3 4  N PHE B 372 ? N PHE B 364 O ILE B 393 ? O ILE B 385 
AB8 1 2  N GLN B 402 ? N GLN B 394 O PHE B 416 ? O PHE B 408 
AB8 2 3  N ILE B 417 ? N ILE B 409 O ALA B 439 ? O ALA B 431 
AB8 3 4  N LEU B 438 ? N LEU B 430 O TYR B 451 ? O TYR B 443 
# 
_pdbx_entry_details.entry_id                   9G89 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A HOH 709 ? ? O A HOH 810  ? ? 1.17 
2 1 O   B HOH 752 ? ? O B HOH 913  ? ? 1.34 
3 1 O   B HOH 705 ? ? O B HOH 1010 ? ? 1.57 
4 1 CB  A SER 194 ? ? O A HOH 703  ? ? 1.75 
5 1 SG  A CYS 145 ? ? O A HOH 1071 ? ? 1.84 
6 1 N   A GLY 419 ? ? O A HOH 701  ? ? 1.93 
7 1 N   B GLY 419 ? ? O B HOH 701  ? ? 2.02 
8 1 OE1 A GLU 534 ? ? O A HOH 702  ? ? 2.04 
9 1 O   A HOH 825 ? ? O A HOH 829  ? ? 2.11 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CB A LEU 41  ? ? CG A LEU 41  ? ? CD1 A LEU 41  ? ? 100.52 111.00 -10.48 1.70 N 
2  1 NE A ARG 49  ? ? CZ A ARG 49  ? ? NH2 A ARG 49  ? ? 117.02 120.30 -3.28  0.50 N 
3  1 CG A ARG 73  ? ? CD A ARG 73  ? ? NE  A ARG 73  ? ? 91.43  111.80 -20.37 2.10 N 
4  1 NE A ARG 73  ? ? CZ A ARG 73  ? ? NH2 A ARG 73  ? ? 117.30 120.30 -3.00  0.50 N 
5  1 CB A LYS 109 ? ? CG A LYS 109 ? ? CD  A LYS 109 ? ? 129.23 111.60 17.63  2.60 N 
6  1 NE A ARG 127 ? ? CZ A ARG 127 ? ? NH2 A ARG 127 ? ? 116.90 120.30 -3.40  0.50 N 
7  1 CG A ARG 129 ? ? CD A ARG 129 ? ? NE  A ARG 129 ? ? 127.71 111.80 15.91  2.10 N 
8  1 CG A ARG 147 ? ? CD A ARG 147 ? ? NE  A ARG 147 ? ? 94.74  111.80 -17.06 2.10 N 
9  1 CD A ARG 147 ? ? NE A ARG 147 ? ? CZ  A ARG 147 ? ? 133.38 123.60 9.78   1.40 N 
10 1 NE A ARG 164 ? ? CZ A ARG 164 ? ? NH2 A ARG 164 ? ? 117.30 120.30 -3.00  0.50 N 
11 1 CB A ASP 418 ? ? CA A ASP 418 ? ? C   A ASP 418 ? ? 128.81 110.40 18.41  2.00 N 
12 1 NE B ARG 49  ? ? CZ B ARG 49  ? ? NH2 B ARG 49  ? ? 116.89 120.30 -3.41  0.50 N 
13 1 CG B ARG 73  ? ? CD B ARG 73  ? ? NE  B ARG 73  ? ? 90.45  111.80 -21.35 2.10 N 
14 1 CG B ARG 147 ? ? CD B ARG 147 ? ? NE  B ARG 147 ? ? 94.27  111.80 -17.53 2.10 N 
15 1 CB B LEU 220 ? ? CG B LEU 220 ? ? CD1 B LEU 220 ? ? 122.02 111.00 11.02  1.70 N 
16 1 CB B ASP 418 ? ? CA B ASP 418 ? ? C   B ASP 418 ? ? 128.35 110.40 17.95  2.00 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 48  ? ? -110.13 -76.33  
2  1 ASP A 56  ? ? 61.51   62.91   
3  1 ASP A 77  ? ? -150.03 83.68   
4  1 LEU A 240 ? ? -170.25 134.83  
5  1 TRP A 309 ? ? -118.76 -106.92 
6  1 ALA A 318 ? ? -73.42  -76.11  
7  1 PHE A 340 ? ? -116.29 69.73   
8  1 PHE A 343 ? ? -114.19 73.48   
9  1 ASP A 387 ? ? -90.13  47.46   
10 1 SER A 405 ? ? -131.49 -44.28  
11 1 ARG A 416 ? ? -145.53 40.17   
12 1 ILE A 509 ? ? -105.97 -94.37  
13 1 ARG B 48  ? ? -113.44 -75.36  
14 1 ASP B 56  ? ? 61.55   63.04   
15 1 ASP B 77  ? ? -154.27 84.44   
16 1 TRP B 309 ? ? -121.28 -106.01 
17 1 ALA B 318 ? ? -75.20  -76.04  
18 1 PHE B 340 ? ? -117.22 70.08   
19 1 PHE B 343 ? ? -112.41 71.52   
20 1 ASP B 387 ? ? -90.58  55.86   
21 1 ARG B 416 ? ? -142.83 39.07   
22 1 ILE B 509 ? ? -105.90 -93.81  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 73  ? ? 0.080 'SIDE CHAIN' 
2 1 ARG A 147 ? ? 0.074 'SIDE CHAIN' 
3 1 ARG A 366 ? ? 0.105 'SIDE CHAIN' 
4 1 ARG B 127 ? ? 0.075 'SIDE CHAIN' 
5 1 ARG B 366 ? ? 0.114 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -7 ? A MET 1  
2  1 Y 1 A TRP -6 ? A TRP 2  
3  1 Y 1 A SER -5 ? A SER 3  
4  1 Y 1 A HIS -4 ? A HIS 4  
5  1 Y 1 A PRO -3 ? A PRO 5  
6  1 Y 1 A GLN -2 ? A GLN 6  
7  1 Y 1 A PHE -1 ? A PHE 7  
8  1 Y 1 A GLU 0  ? A GLU 8  
9  1 Y 1 A LYS 1  ? A LYS 9  
10 1 Y 1 A ALA 2  ? A ALA 10 
11 1 Y 1 A PRO 3  ? A PRO 11 
12 1 Y 1 A THR 4  ? A THR 12 
13 1 Y 1 A ALA 5  ? A ALA 13 
14 1 Y 1 A THR 6  ? A THR 14 
15 1 Y 1 A GLN 7  ? A GLN 15 
16 1 Y 1 A GLU 8  ? A GLU 16 
17 1 Y 1 A PRO 9  ? A PRO 17 
18 1 Y 1 A VAL 10 ? A VAL 18 
19 1 Y 1 A PRO 11 ? A PRO 19 
20 1 Y 1 A VAL 12 ? A VAL 20 
21 1 Y 1 A PRO 13 ? A PRO 21 
22 1 Y 1 A VAL 14 ? A VAL 22 
23 1 Y 1 A THR 15 ? A THR 23 
24 1 Y 1 A SER 16 ? A SER 24 
25 1 Y 1 A LYS 17 ? A LYS 25 
26 1 Y 1 A ALA 18 ? A ALA 26 
27 1 Y 1 A ALA 19 ? A ALA 27 
28 1 Y 1 A PRO 20 ? A PRO 28 
29 1 Y 1 A SER 21 ? A SER 29 
30 1 Y 1 A HIS 22 ? A HIS 30 
31 1 Y 1 A GLY 23 ? A GLY 31 
32 1 Y 1 B MET -7 ? B MET 1  
33 1 Y 1 B TRP -6 ? B TRP 2  
34 1 Y 1 B SER -5 ? B SER 3  
35 1 Y 1 B HIS -4 ? B HIS 4  
36 1 Y 1 B PRO -3 ? B PRO 5  
37 1 Y 1 B GLN -2 ? B GLN 6  
38 1 Y 1 B PHE -1 ? B PHE 7  
39 1 Y 1 B GLU 0  ? B GLU 8  
40 1 Y 1 B LYS 1  ? B LYS 9  
41 1 Y 1 B ALA 2  ? B ALA 10 
42 1 Y 1 B PRO 3  ? B PRO 11 
43 1 Y 1 B THR 4  ? B THR 12 
44 1 Y 1 B ALA 5  ? B ALA 13 
45 1 Y 1 B THR 6  ? B THR 14 
46 1 Y 1 B GLN 7  ? B GLN 15 
47 1 Y 1 B GLU 8  ? B GLU 16 
48 1 Y 1 B PRO 9  ? B PRO 17 
49 1 Y 1 B VAL 10 ? B VAL 18 
50 1 Y 1 B PRO 11 ? B PRO 19 
51 1 Y 1 B VAL 12 ? B VAL 20 
52 1 Y 1 B PRO 13 ? B PRO 21 
53 1 Y 1 B VAL 14 ? B VAL 22 
54 1 Y 1 B THR 15 ? B THR 23 
55 1 Y 1 B SER 16 ? B SER 24 
56 1 Y 1 B LYS 17 ? B LYS 25 
57 1 Y 1 B ALA 18 ? B ALA 26 
58 1 Y 1 B ALA 19 ? B ALA 27 
59 1 Y 1 B PRO 20 ? B PRO 28 
60 1 Y 1 B SER 21 ? B SER 29 
61 1 Y 1 B HIS 22 ? B HIS 30 
62 1 Y 1 B GLY 23 ? B GLY 31 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FE2 FE   FE N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
GOL C1   C  N N 138 
GOL O1   O  N N 139 
GOL C2   C  N N 140 
GOL O2   O  N N 141 
GOL C3   C  N N 142 
GOL O3   O  N N 143 
GOL H11  H  N N 144 
GOL H12  H  N N 145 
GOL HO1  H  N N 146 
GOL H2   H  N N 147 
GOL HO2  H  N N 148 
GOL H31  H  N N 149 
GOL H32  H  N N 150 
GOL HO3  H  N N 151 
HIS N    N  N N 152 
HIS CA   C  N S 153 
HIS C    C  N N 154 
HIS O    O  N N 155 
HIS CB   C  N N 156 
HIS CG   C  Y N 157 
HIS ND1  N  Y N 158 
HIS CD2  C  Y N 159 
HIS CE1  C  Y N 160 
HIS NE2  N  Y N 161 
HIS OXT  O  N N 162 
HIS H    H  N N 163 
HIS H2   H  N N 164 
HIS HA   H  N N 165 
HIS HB2  H  N N 166 
HIS HB3  H  N N 167 
HIS HD1  H  N N 168 
HIS HD2  H  N N 169 
HIS HE1  H  N N 170 
HIS HE2  H  N N 171 
HIS HXT  H  N N 172 
HOH O    O  N N 173 
HOH H1   H  N N 174 
HOH H2   H  N N 175 
ILE N    N  N N 176 
ILE CA   C  N S 177 
ILE C    C  N N 178 
ILE O    O  N N 179 
ILE CB   C  N S 180 
ILE CG1  C  N N 181 
ILE CG2  C  N N 182 
ILE CD1  C  N N 183 
ILE OXT  O  N N 184 
ILE H    H  N N 185 
ILE H2   H  N N 186 
ILE HA   H  N N 187 
ILE HB   H  N N 188 
ILE HG12 H  N N 189 
ILE HG13 H  N N 190 
ILE HG21 H  N N 191 
ILE HG22 H  N N 192 
ILE HG23 H  N N 193 
ILE HD11 H  N N 194 
ILE HD12 H  N N 195 
ILE HD13 H  N N 196 
ILE HXT  H  N N 197 
LEU N    N  N N 198 
LEU CA   C  N S 199 
LEU C    C  N N 200 
LEU O    O  N N 201 
LEU CB   C  N N 202 
LEU CG   C  N N 203 
LEU CD1  C  N N 204 
LEU CD2  C  N N 205 
LEU OXT  O  N N 206 
LEU H    H  N N 207 
LEU H2   H  N N 208 
LEU HA   H  N N 209 
LEU HB2  H  N N 210 
LEU HB3  H  N N 211 
LEU HG   H  N N 212 
LEU HD11 H  N N 213 
LEU HD12 H  N N 214 
LEU HD13 H  N N 215 
LEU HD21 H  N N 216 
LEU HD22 H  N N 217 
LEU HD23 H  N N 218 
LEU HXT  H  N N 219 
LYS N    N  N N 220 
LYS CA   C  N S 221 
LYS C    C  N N 222 
LYS O    O  N N 223 
LYS CB   C  N N 224 
LYS CG   C  N N 225 
LYS CD   C  N N 226 
LYS CE   C  N N 227 
LYS NZ   N  N N 228 
LYS OXT  O  N N 229 
LYS H    H  N N 230 
LYS H2   H  N N 231 
LYS HA   H  N N 232 
LYS HB2  H  N N 233 
LYS HB3  H  N N 234 
LYS HG2  H  N N 235 
LYS HG3  H  N N 236 
LYS HD2  H  N N 237 
LYS HD3  H  N N 238 
LYS HE2  H  N N 239 
LYS HE3  H  N N 240 
LYS HZ1  H  N N 241 
LYS HZ2  H  N N 242 
LYS HZ3  H  N N 243 
LYS HXT  H  N N 244 
MET N    N  N N 245 
MET CA   C  N S 246 
MET C    C  N N 247 
MET O    O  N N 248 
MET CB   C  N N 249 
MET CG   C  N N 250 
MET SD   S  N N 251 
MET CE   C  N N 252 
MET OXT  O  N N 253 
MET H    H  N N 254 
MET H2   H  N N 255 
MET HA   H  N N 256 
MET HB2  H  N N 257 
MET HB3  H  N N 258 
MET HG2  H  N N 259 
MET HG3  H  N N 260 
MET HE1  H  N N 261 
MET HE2  H  N N 262 
MET HE3  H  N N 263 
MET HXT  H  N N 264 
PHE N    N  N N 265 
PHE CA   C  N S 266 
PHE C    C  N N 267 
PHE O    O  N N 268 
PHE CB   C  N N 269 
PHE CG   C  Y N 270 
PHE CD1  C  Y N 271 
PHE CD2  C  Y N 272 
PHE CE1  C  Y N 273 
PHE CE2  C  Y N 274 
PHE CZ   C  Y N 275 
PHE OXT  O  N N 276 
PHE H    H  N N 277 
PHE H2   H  N N 278 
PHE HA   H  N N 279 
PHE HB2  H  N N 280 
PHE HB3  H  N N 281 
PHE HD1  H  N N 282 
PHE HD2  H  N N 283 
PHE HE1  H  N N 284 
PHE HE2  H  N N 285 
PHE HZ   H  N N 286 
PHE HXT  H  N N 287 
PRO N    N  N N 288 
PRO CA   C  N S 289 
PRO C    C  N N 290 
PRO O    O  N N 291 
PRO CB   C  N N 292 
PRO CG   C  N N 293 
PRO CD   C  N N 294 
PRO OXT  O  N N 295 
PRO H    H  N N 296 
PRO HA   H  N N 297 
PRO HB2  H  N N 298 
PRO HB3  H  N N 299 
PRO HG2  H  N N 300 
PRO HG3  H  N N 301 
PRO HD2  H  N N 302 
PRO HD3  H  N N 303 
PRO HXT  H  N N 304 
SER N    N  N N 305 
SER CA   C  N S 306 
SER C    C  N N 307 
SER O    O  N N 308 
SER CB   C  N N 309 
SER OG   O  N N 310 
SER OXT  O  N N 311 
SER H    H  N N 312 
SER H2   H  N N 313 
SER HA   H  N N 314 
SER HB2  H  N N 315 
SER HB3  H  N N 316 
SER HG   H  N N 317 
SER HXT  H  N N 318 
THR N    N  N N 319 
THR CA   C  N S 320 
THR C    C  N N 321 
THR O    O  N N 322 
THR CB   C  N R 323 
THR OG1  O  N N 324 
THR CG2  C  N N 325 
THR OXT  O  N N 326 
THR H    H  N N 327 
THR H2   H  N N 328 
THR HA   H  N N 329 
THR HB   H  N N 330 
THR HG1  H  N N 331 
THR HG21 H  N N 332 
THR HG22 H  N N 333 
THR HG23 H  N N 334 
THR HXT  H  N N 335 
TRP N    N  N N 336 
TRP CA   C  N S 337 
TRP C    C  N N 338 
TRP O    O  N N 339 
TRP CB   C  N N 340 
TRP CG   C  Y N 341 
TRP CD1  C  Y N 342 
TRP CD2  C  Y N 343 
TRP NE1  N  Y N 344 
TRP CE2  C  Y N 345 
TRP CE3  C  Y N 346 
TRP CZ2  C  Y N 347 
TRP CZ3  C  Y N 348 
TRP CH2  C  Y N 349 
TRP OXT  O  N N 350 
TRP H    H  N N 351 
TRP H2   H  N N 352 
TRP HA   H  N N 353 
TRP HB2  H  N N 354 
TRP HB3  H  N N 355 
TRP HD1  H  N N 356 
TRP HE1  H  N N 357 
TRP HE3  H  N N 358 
TRP HZ2  H  N N 359 
TRP HZ3  H  N N 360 
TRP HH2  H  N N 361 
TRP HXT  H  N N 362 
TYR N    N  N N 363 
TYR CA   C  N S 364 
TYR C    C  N N 365 
TYR O    O  N N 366 
TYR CB   C  N N 367 
TYR CG   C  Y N 368 
TYR CD1  C  Y N 369 
TYR CD2  C  Y N 370 
TYR CE1  C  Y N 371 
TYR CE2  C  Y N 372 
TYR CZ   C  Y N 373 
TYR OH   O  N N 374 
TYR OXT  O  N N 375 
TYR H    H  N N 376 
TYR H2   H  N N 377 
TYR HA   H  N N 378 
TYR HB2  H  N N 379 
TYR HB3  H  N N 380 
TYR HD1  H  N N 381 
TYR HD2  H  N N 382 
TYR HE1  H  N N 383 
TYR HE2  H  N N 384 
TYR HH   H  N N 385 
TYR HXT  H  N N 386 
V55 CAI  C  Y N 387 
V55 CAG  C  Y N 388 
V55 CAK  C  Y N 389 
V55 CAJ  C  Y N 390 
V55 CAF  C  Y N 391 
V55 OAB  O  N N 392 
V55 CAE  C  Y N 393 
V55 CAD  C  N N 394 
V55 CAA  C  N N 395 
V55 OAH  O  N N 396 
V55 OAC  O  N N 397 
V55 HAG  H  N N 398 
V55 HAD  H  N N 399 
V55 HAE  H  N N 400 
V55 HAF  H  N N 401 
V55 HAC  H  N N 402 
V55 HAA1 H  N N 403 
V55 HAA2 H  N N 404 
V55 HAA3 H  N N 405 
VAL N    N  N N 406 
VAL CA   C  N S 407 
VAL C    C  N N 408 
VAL O    O  N N 409 
VAL CB   C  N N 410 
VAL CG1  C  N N 411 
VAL CG2  C  N N 412 
VAL OXT  O  N N 413 
VAL H    H  N N 414 
VAL H2   H  N N 415 
VAL HA   H  N N 416 
VAL HB   H  N N 417 
VAL HG11 H  N N 418 
VAL HG12 H  N N 419 
VAL HG13 H  N N 420 
VAL HG21 H  N N 421 
VAL HG22 H  N N 422 
VAL HG23 H  N N 423 
VAL HXT  H  N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PRO N   CA   sing N N 273 
PRO N   CD   sing N N 274 
PRO N   H    sing N N 275 
PRO CA  C    sing N N 276 
PRO CA  CB   sing N N 277 
PRO CA  HA   sing N N 278 
PRO C   O    doub N N 279 
PRO C   OXT  sing N N 280 
PRO CB  CG   sing N N 281 
PRO CB  HB2  sing N N 282 
PRO CB  HB3  sing N N 283 
PRO CG  CD   sing N N 284 
PRO CG  HG2  sing N N 285 
PRO CG  HG3  sing N N 286 
PRO CD  HD2  sing N N 287 
PRO CD  HD3  sing N N 288 
PRO OXT HXT  sing N N 289 
SER N   CA   sing N N 290 
SER N   H    sing N N 291 
SER N   H2   sing N N 292 
SER CA  C    sing N N 293 
SER CA  CB   sing N N 294 
SER CA  HA   sing N N 295 
SER C   O    doub N N 296 
SER C   OXT  sing N N 297 
SER CB  OG   sing N N 298 
SER CB  HB2  sing N N 299 
SER CB  HB3  sing N N 300 
SER OG  HG   sing N N 301 
SER OXT HXT  sing N N 302 
THR N   CA   sing N N 303 
THR N   H    sing N N 304 
THR N   H2   sing N N 305 
THR CA  C    sing N N 306 
THR CA  CB   sing N N 307 
THR CA  HA   sing N N 308 
THR C   O    doub N N 309 
THR C   OXT  sing N N 310 
THR CB  OG1  sing N N 311 
THR CB  CG2  sing N N 312 
THR CB  HB   sing N N 313 
THR OG1 HG1  sing N N 314 
THR CG2 HG21 sing N N 315 
THR CG2 HG22 sing N N 316 
THR CG2 HG23 sing N N 317 
THR OXT HXT  sing N N 318 
TRP N   CA   sing N N 319 
TRP N   H    sing N N 320 
TRP N   H2   sing N N 321 
TRP CA  C    sing N N 322 
TRP CA  CB   sing N N 323 
TRP CA  HA   sing N N 324 
TRP C   O    doub N N 325 
TRP C   OXT  sing N N 326 
TRP CB  CG   sing N N 327 
TRP CB  HB2  sing N N 328 
TRP CB  HB3  sing N N 329 
TRP CG  CD1  doub Y N 330 
TRP CG  CD2  sing Y N 331 
TRP CD1 NE1  sing Y N 332 
TRP CD1 HD1  sing N N 333 
TRP CD2 CE2  doub Y N 334 
TRP CD2 CE3  sing Y N 335 
TRP NE1 CE2  sing Y N 336 
TRP NE1 HE1  sing N N 337 
TRP CE2 CZ2  sing Y N 338 
TRP CE3 CZ3  doub Y N 339 
TRP CE3 HE3  sing N N 340 
TRP CZ2 CH2  doub Y N 341 
TRP CZ2 HZ2  sing N N 342 
TRP CZ3 CH2  sing Y N 343 
TRP CZ3 HZ3  sing N N 344 
TRP CH2 HH2  sing N N 345 
TRP OXT HXT  sing N N 346 
TYR N   CA   sing N N 347 
TYR N   H    sing N N 348 
TYR N   H2   sing N N 349 
TYR CA  C    sing N N 350 
TYR CA  CB   sing N N 351 
TYR CA  HA   sing N N 352 
TYR C   O    doub N N 353 
TYR C   OXT  sing N N 354 
TYR CB  CG   sing N N 355 
TYR CB  HB2  sing N N 356 
TYR CB  HB3  sing N N 357 
TYR CG  CD1  doub Y N 358 
TYR CG  CD2  sing Y N 359 
TYR CD1 CE1  sing Y N 360 
TYR CD1 HD1  sing N N 361 
TYR CD2 CE2  doub Y N 362 
TYR CD2 HD2  sing N N 363 
TYR CE1 CZ   doub Y N 364 
TYR CE1 HE1  sing N N 365 
TYR CE2 CZ   sing Y N 366 
TYR CE2 HE2  sing N N 367 
TYR CZ  OH   sing N N 368 
TYR OH  HH   sing N N 369 
TYR OXT HXT  sing N N 370 
V55 CAK CAG  doub Y N 371 
V55 CAK CAJ  sing Y N 372 
V55 CAK OAH  sing N N 373 
V55 CAG CAI  sing Y N 374 
V55 CAI CAD  sing N N 375 
V55 CAI CAE  doub Y N 376 
V55 CAD OAB  doub N N 377 
V55 CAF CAJ  doub Y N 378 
V55 CAF CAE  sing Y N 379 
V55 CAJ OAC  sing N N 380 
V55 CAA OAH  sing N N 381 
V55 CAG HAG  sing N N 382 
V55 CAD HAD  sing N N 383 
V55 CAE HAE  sing N N 384 
V55 CAF HAF  sing N N 385 
V55 OAC HAC  sing N N 386 
V55 CAA HAA1 sing N N 387 
V55 CAA HAA2 sing N N 388 
V55 CAA HAA3 sing N N 389 
VAL N   CA   sing N N 390 
VAL N   H    sing N N 391 
VAL N   H2   sing N N 392 
VAL CA  C    sing N N 393 
VAL CA  CB   sing N N 394 
VAL CA  HA   sing N N 395 
VAL C   O    doub N N 396 
VAL C   OXT  sing N N 397 
VAL CB  CG1  sing N N 398 
VAL CB  CG2  sing N N 399 
VAL CB  HB   sing N N 400 
VAL CG1 HG11 sing N N 401 
VAL CG1 HG12 sing N N 402 
VAL CG1 HG13 sing N N 403 
VAL CG2 HG21 sing N N 404 
VAL CG2 HG22 sing N N 405 
VAL CG2 HG23 sing N N 406 
VAL OXT HXT  sing N N 407 
# 
_pdbx_audit_support.funding_organization   'Austrian Science Fund' 
_pdbx_audit_support.country                Austria 
_pdbx_audit_support.grant_number           P33687 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9G89 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013951 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004627 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011810 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009886 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
FE 26 26 11.7738 4.7611  7.3600 0.3072  3.5235 15.3535 2.3054 76.8805 1.2402   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0650   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . TYR A 1 32  ? 2.307   19.113  7.151   1   65.029 ? 24   TYR A N   1 
ATOM   2    C  CA  . TYR A 1 32  ? 1.629   19.439  8.436   1   61.904 ? 24   TYR A CA  1 
ATOM   3    C  C   . TYR A 1 32  ? 0.679   18.3    8.792   1   58.673 ? 24   TYR A C   1 
ATOM   4    O  O   . TYR A 1 32  ? 0.638   17.918  9.959   1   56.574 ? 24   TYR A O   1 
ATOM   5    C  CB  . TYR A 1 32  ? 0.893   20.785  8.525   1   59.15  ? 24   TYR A CB  1 
ATOM   6    N  N   . VAL A 1 33  ? -0.058  17.783  7.79    1   56.607 ? 25   VAL A N   1 
ATOM   7    C  CA  . VAL A 1 33  ? -0.916  16.608  7.921   1   50.902 ? 25   VAL A CA  1 
ATOM   8    C  C   . VAL A 1 33  ? -0.419  15.531  6.953   1   50.634 ? 25   VAL A C   1 
ATOM   9    O  O   . VAL A 1 33  ? -0.308  15.791  5.746   1   48.955 ? 25   VAL A O   1 
ATOM   10   C  CB  . VAL A 1 33  ? -2.439  16.857  7.772   1   51.187 ? 25   VAL A CB  1 
ATOM   11   C  CG1 . VAL A 1 33  ? -3.28   15.588  7.986   1   46.146 ? 25   VAL A CG1 1 
ATOM   12   C  CG2 . VAL A 1 33  ? -2.927  17.952  8.722   1   48.627 ? 25   VAL A CG2 1 
ATOM   13   N  N   . HIS A 1 34  ? -0.162  14.32   7.487   1   34.864 ? 26   HIS A N   1 
ATOM   14   C  CA  . HIS A 1 34  ? 0.285   13.208  6.656   1   35.201 ? 26   HIS A CA  1 
ATOM   15   C  C   . HIS A 1 34  ? -0.872  12.744  5.762   1   27.913 ? 26   HIS A C   1 
ATOM   16   O  O   . HIS A 1 34  ? -1.955  12.499  6.273   1   31.509 ? 26   HIS A O   1 
ATOM   17   C  CB  . HIS A 1 34  ? 0.836   12.052  7.515   1   29.1   ? 26   HIS A CB  1 
ATOM   18   C  CG  . HIS A 1 34  ? 1.704   11.138  6.699   1   31.75  ? 26   HIS A CG  1 
ATOM   19   N  ND1 . HIS A 1 34  ? 1.228   10.284  5.724   1   30.598 ? 26   HIS A ND1 1 
ATOM   20   C  CD2 . HIS A 1 34  ? 3.039   10.978  6.715   1   31.271 ? 26   HIS A CD2 1 
ATOM   21   C  CE1 . HIS A 1 34  ? 2.24    9.636   5.161   1   28.158 ? 26   HIS A CE1 1 
ATOM   22   N  NE2 . HIS A 1 34  ? 3.344   10.036  5.767   1   30.01  ? 26   HIS A NE2 1 
ATOM   23   N  N   . PRO A 1 35  ? -0.702  12.615  4.411   1   27.992 ? 27   PRO A N   1 
ATOM   24   C  CA  . PRO A 1 35  ? -1.766  12.121  3.537   1   27.538 ? 27   PRO A CA  1 
ATOM   25   C  C   . PRO A 1 35  ? -2.445  10.831  3.979   1   30.899 ? 27   PRO A C   1 
ATOM   26   O  O   . PRO A 1 35  ? -3.651  10.7    3.855   1   29.116 ? 27   PRO A O   1 
ATOM   27   C  CB  . PRO A 1 35  ? -1.117  11.973  2.144   1   29.506 ? 27   PRO A CB  1 
ATOM   28   C  CG  . PRO A 1 35  ? 0.028   12.954  2.215   1   29.161 ? 27   PRO A CG  1 
ATOM   29   C  CD  . PRO A 1 35  ? 0.489   13.036  3.655   1   28.809 ? 27   PRO A CD  1 
ATOM   30   N  N   . THR A 1 36  ? -1.673  9.844   4.483   1   25.031 ? 28   THR A N   1 
ATOM   31   C  CA  . THR A 1 36  ? -2.259  8.579   4.896   1   25.535 ? 28   THR A CA  1 
ATOM   32   C  C   . THR A 1 36  ? -3.077  8.71    6.18    1   26.754 ? 28   THR A C   1 
ATOM   33   O  O   . THR A 1 36  ? -3.859  7.809   6.453   1   28.298 ? 28   THR A O   1 
ATOM   34   C  CB  . THR A 1 36  ? -1.221  7.448   4.992   1   26.071 ? 28   THR A CB  1 
ATOM   35   O  OG1 . THR A 1 36  ? -0.36   7.83    6.062   1   25.896 ? 28   THR A OG1 1 
ATOM   36   C  CG2 . THR A 1 36  ? -0.482  7.319   3.668   1   23.705 ? 28   THR A CG2 1 
ATOM   37   N  N   . ASP A 1 37  ? -2.861  9.795   6.941   1   28.917 ? 29   ASP A N   1 
ATOM   38   C  CA  . ASP A 1 37  ? -3.575  10.009  8.203   1   29.045 ? 29   ASP A CA  1 
ATOM   39   C  C   . ASP A 1 37  ? -5.03   10.413  7.999   1   34.785 ? 29   ASP A C   1 
ATOM   40   O  O   . ASP A 1 37  ? -5.812  10.287  8.929   1   35.11  ? 29   ASP A O   1 
ATOM   41   C  CB  . ASP A 1 37  ? -2.812  10.929  9.138   1   29.603 ? 29   ASP A CB  1 
ATOM   42   C  CG  . ASP A 1 37  ? -1.586  10.28   9.751   1   30.275 ? 29   ASP A CG  1 
ATOM   43   O  OD1 . ASP A 1 37  ? -1.443  9.056   9.54    1   31.292 ? 29   ASP A OD1 1 
ATOM   44   O  OD2 . ASP A 1 37  ? -0.79   11.012  10.363  1   31.506 ? 29   ASP A OD2 1 
ATOM   45   N  N   . ILE A 1 38  ? -5.39   10.861  6.79    1   31.248 ? 30   ILE A N   1 
ATOM   46   C  CA  . ILE A 1 38  ? -6.782  11.182  6.502   1   34.916 ? 30   ILE A CA  1 
ATOM   47   C  C   . ILE A 1 38  ? -7.488  9.999   5.852   1   37.693 ? 30   ILE A C   1 
ATOM   48   O  O   . ILE A 1 38  ? -8.65   10.122  5.48    1   36.336 ? 30   ILE A O   1 
ATOM   49   C  CB  . ILE A 1 38  ? -6.946  12.502  5.709   1   35.04  ? 30   ILE A CB  1 
ATOM   50   C  CG1 . ILE A 1 38  ? -6.459  12.394  4.252   1   33.993 ? 30   ILE A CG1 1 
ATOM   51   C  CG2 . ILE A 1 38  ? -6.295  13.663  6.48    1   39.948 ? 30   ILE A CG2 1 
ATOM   52   C  CD1 . ILE A 1 38  ? -7.132  13.368  3.291   1   35.309 ? 30   ILE A CD1 1 
ATOM   53   N  N   . LEU A 1 39  ? -6.794  8.867   5.652   1   31.841 ? 31   LEU A N   1 
ATOM   54   C  CA  . LEU A 1 39  ? -7.457  7.636   5.252   1   27.438 ? 31   LEU A CA  1 
ATOM   55   C  C   . LEU A 1 39  ? -8.356  7.148   6.377   1   31.067 ? 31   LEU A C   1 
ATOM   56   O  O   . LEU A 1 39  ? -7.918  7.17    7.529   1   29.439 ? 31   LEU A O   1 
ATOM   57   C  CB  . LEU A 1 39  ? -6.558  6.505   4.746   1   25.222 ? 31   LEU A CB  1 
ATOM   58   C  CG  . LEU A 1 39  ? -5.686  6.825   3.529   1   31.296 ? 31   LEU A CG  1 
ATOM   59   C  CD1 . LEU A 1 39  ? -4.538  5.779   3.403   1   31.287 ? 31   LEU A CD1 1 
ATOM   60   C  CD2 . LEU A 1 39  ? -6.524  6.892   2.254   1   34.34  ? 31   LEU A CD2 1 
ATOM   61   N  N   . PRO A 1 40  ? -9.601  6.691   6.066   1   29.188 ? 32   PRO A N   1 
ATOM   62   C  CA  . PRO A 1 40  ? -10.576 6.363   7.1     1   35.3   ? 32   PRO A CA  1 
ATOM   63   C  C   . PRO A 1 40  ? -10.21  5.137   7.914   1   35.57  ? 32   PRO A C   1 
ATOM   64   O  O   . PRO A 1 40  ? -9.708  4.147   7.384   1   33.343 ? 32   PRO A O   1 
ATOM   65   C  CB  . PRO A 1 40  ? -11.884 6.16    6.331   1   36.023 ? 32   PRO A CB  1 
ATOM   66   C  CG  . PRO A 1 40  ? -11.407 5.745   4.944   1   35.422 ? 32   PRO A CG  1 
ATOM   67   C  CD  . PRO A 1 40  ? -10.16  6.535   4.703   1   32.065 ? 32   PRO A CD  1 
ATOM   68   N  N   . SER A 1 41  ? -10.5   5.229   9.21    1   35.718 ? 33   SER A N   1 
ATOM   69   C  CA  . SER A 1 41  ? -10.401 4.113   10.129  1   34.315 ? 33   SER A CA  1 
ATOM   70   C  C   . SER A 1 41  ? -11.811 3.567   10.34   1   37.288 ? 33   SER A C   1 
ATOM   71   O  O   . SER A 1 41  ? -12.77  4.365   10.424  1   32.586 ? 33   SER A O   1 
ATOM   72   C  CB  . SER A 1 41  ? -9.866  4.597   11.47   1   36.373 ? 33   SER A CB  1 
ATOM   73   O  OG  . SER A 1 41  ? -9.889  3.512   12.4    1   29.598 ? 33   SER A OG  1 
ATOM   74   N  N   . GLY A 1 42  ? -11.879 2.237   10.531  1   26.479 ? 34   GLY A N   1 
ATOM   75   C  CA  . GLY A 1 42  ? -13.077 1.506   10.902  1   27.907 ? 34   GLY A CA  1 
ATOM   76   C  C   . GLY A 1 42  ? -13.206 1.366   12.426  1   29.349 ? 34   GLY A C   1 
ATOM   77   O  O   . GLY A 1 42  ? -14.124 0.687   12.886  1   32.724 ? 34   GLY A O   1 
ATOM   78   N  N   . TRP A 1 43  ? -12.303 1.987   13.202  1   22.968 ? 35   TRP A N   1 
ATOM   79   C  CA  . TRP A 1 43  ? -12.341 1.826   14.655  1   22.727 ? 35   TRP A CA  1 
ATOM   80   C  C   . TRP A 1 43  ? -13.21  2.902   15.278  1   24.699 ? 35   TRP A C   1 
ATOM   81   O  O   . TRP A 1 43  ? -12.971 4.08    15.007  1   26.11  ? 35   TRP A O   1 
ATOM   82   C  CB  . TRP A 1 43  ? -10.933 1.889   15.278  1   21.479 ? 35   TRP A CB  1 
ATOM   83   C  CG  . TRP A 1 43  ? -10.286 0.528   15.301  1   19.559 ? 35   TRP A CG  1 
ATOM   84   C  CD1 . TRP A 1 43  ? -9.696  -0.147  14.252  1   21.299 ? 35   TRP A CD1 1 
ATOM   85   C  CD2 . TRP A 1 43  ? -10.148 -0.323  16.457  1   20.458 ? 35   TRP A CD2 1 
ATOM   86   N  NE1 . TRP A 1 43  ? -9.218  -1.363  14.693  1   21.741 ? 35   TRP A NE1 1 
ATOM   87   C  CE2 . TRP A 1 43  ? -9.485  -1.508  16.033  1   19.67  ? 35   TRP A CE2 1 
ATOM   88   C  CE3 . TRP A 1 43  ? -10.528 -0.202  17.806  1   22.892 ? 35   TRP A CE3 1 
ATOM   89   C  CZ2 . TRP A 1 43  ? -9.189  -2.549  16.918  1   21.059 ? 35   TRP A CZ2 1 
ATOM   90   C  CZ3 . TRP A 1 43  ? -10.257 -1.254  18.673  1   21.916 ? 35   TRP A CZ3 1 
ATOM   91   C  CH2 . TRP A 1 43  ? -9.581  -2.396  18.237  1   20.717 ? 35   TRP A CH2 1 
ATOM   92   N  N   . PRO A 1 44  ? -14.102 2.563   16.25   1   24.124 ? 36   PRO A N   1 
ATOM   93   C  CA  . PRO A 1 44  ? -14.633 3.592   17.134  1   25.829 ? 36   PRO A CA  1 
ATOM   94   C  C   . PRO A 1 44  ? -13.568 4       18.159  1   24.143 ? 36   PRO A C   1 
ATOM   95   O  O   . PRO A 1 44  ? -12.572 3.296   18.328  1   24.995 ? 36   PRO A O   1 
ATOM   96   C  CB  . PRO A 1 44  ? -15.803 2.928   17.804  1   24.298 ? 36   PRO A CB  1 
ATOM   97   C  CG  . PRO A 1 44  ? -15.401 1.474   17.839  1   25.533 ? 36   PRO A CG  1 
ATOM   98   C  CD  . PRO A 1 44  ? -14.484 1.195   16.644  1   21.74  ? 36   PRO A CD  1 
ATOM   99   N  N   . THR A 1 45  ? -13.765 5.119   18.847  1   24.531 ? 37   THR A N   1 
ATOM   100  C  CA  . THR A 1 45  ? -12.819 5.5     19.897  1   27.762 ? 37   THR A CA  1 
ATOM   101  C  C   . THR A 1 45  ? -12.922 4.489   21.043  1   25.016 ? 37   THR A C   1 
ATOM   102  O  O   . THR A 1 45  ? -13.978 4.356   21.647  1   26.643 ? 37   THR A O   1 
ATOM   103  C  CB  . THR A 1 45  ? -13.034 6.921   20.42   1   27.351 ? 37   THR A CB  1 
ATOM   104  O  OG1 . THR A 1 45  ? -12.9   7.706   19.24   1   30.757 ? 37   THR A OG1 1 
ATOM   105  C  CG2 . THR A 1 45  ? -11.947 7.33    21.406  1   24.827 ? 37   THR A CG2 1 
ATOM   106  N  N   . ALA A 1 46  ? -11.809 3.786   21.31   1   22.733 ? 38   ALA A N   1 
ATOM   107  C  CA  . ALA A 1 46  ? -11.83  2.725   22.316  1   24.594 ? 38   ALA A CA  1 
ATOM   108  C  C   . ALA A 1 46  ? -10.873 3.1     23.444  1   24.477 ? 38   ALA A C   1 
ATOM   109  O  O   . ALA A 1 46  ? -9.678  2.794   23.377  1   22.972 ? 38   ALA A O   1 
ATOM   110  C  CB  . ALA A 1 46  ? -11.456 1.398   21.655  1   26.453 ? 38   ALA A CB  1 
ATOM   111  N  N   . THR A 1 47  ? -11.398 3.85    24.432  1   24.256 ? 39   THR A N   1 
ATOM   112  C  CA  . THR A 1 47  ? -10.549 4.375   25.492  1   23.696 ? 39   THR A CA  1 
ATOM   113  C  C   . THR A 1 47  ? -10.281 3.274   26.528  1   23.31  ? 39   THR A C   1 
ATOM   114  O  O   . THR A 1 47  ? -11.08  2.347   26.646  1   23.629 ? 39   THR A O   1 
ATOM   115  C  CB  . THR A 1 47  ? -11.125 5.619   26.175  1   23.31  ? 39   THR A CB  1 
ATOM   116  O  OG1 . THR A 1 47  ? -12.197 5.105   26.976  1   24.007 ? 39   THR A OG1 1 
ATOM   117  C  CG2 . THR A 1 47  ? -11.477 6.726   25.178  1   21.396 ? 39   THR A CG2 1 
ATOM   118  N  N   . ASP A 1 48  ? -9.195  3.439   27.295  1   20.651 ? 40   ASP A N   1 
ATOM   119  C  CA  . ASP A 1 48  ? -9.015  2.737   28.565  1   20.584 ? 40   ASP A CA  1 
ATOM   120  C  C   . ASP A 1 48  ? -9.23   3.77    29.683  1   20.244 ? 40   ASP A C   1 
ATOM   121  O  O   . ASP A 1 48  ? -9.593  4.93    29.398  1   22.099 ? 40   ASP A O   1 
ATOM   122  C  CB  . ASP A 1 48  ? -7.651  2.048   28.601  1   24.515 ? 40   ASP A CB  1 
ATOM   123  C  CG  . ASP A 1 48  ? -6.477  3.002   28.441  1   26.018 ? 40   ASP A CG  1 
ATOM   124  O  OD1 . ASP A 1 48  ? -6.447  4.036   29.162  1   25.715 ? 40   ASP A OD1 1 
ATOM   125  O  OD2 . ASP A 1 48  ? -5.605  2.735   27.585  1   26.459 ? 40   ASP A OD2 1 
ATOM   126  N  N   . LEU A 1 49  ? -9.048  3.374   30.967  1   20.401 ? 41   LEU A N   1 
ATOM   127  C  CA  . LEU A 1 49  ? -9.453  4.276   32.048  1   21.278 ? 41   LEU A CA  1 
ATOM   128  C  C   . LEU A 1 49  ? -8.616  5.57    32.076  1   23.955 ? 41   LEU A C   1 
ATOM   129  O  O   . LEU A 1 49  ? -9.056  6.609   32.576  1   24.666 ? 41   LEU A O   1 
ATOM   130  C  CB  . LEU A 1 49  ? -9.36   3.557   33.393  1   19.195 ? 41   LEU A CB  1 
ATOM   131  C  CG  . LEU A 1 49  ? -10.548 2.682   33.789  1   24.523 ? 41   LEU A CG  1 
ATOM   132  C  CD1 . LEU A 1 49  ? -10.039 2.101   35.11   1   25.689 ? 41   LEU A CD1 1 
ATOM   133  C  CD2 . LEU A 1 49  ? -11.826 3.486   33.991  1   23.258 ? 41   LEU A CD2 1 
ATOM   134  N  N   . SER A 1 50  ? -7.375  5.505   31.566  1   23.558 ? 42   SER A N   1 
ATOM   135  C  CA  . SER A 1 50  ? -6.518  6.672   31.48   1   21.462 ? 42   SER A CA  1 
ATOM   136  C  C   . SER A 1 50  ? -7.052  7.723   30.505  1   22.776 ? 42   SER A C   1 
ATOM   137  O  O   . SER A 1 50  ? -6.605  8.869   30.561  1   23.907 ? 42   SER A O   1 
ATOM   138  C  CB  . SER A 1 50  ? -5.089  6.263   31.167  1   22.047 ? 42   SER A CB  1 
ATOM   139  O  OG  . SER A 1 50  ? -4.933  6.079   29.757  1   23.429 ? 42   SER A OG  1 
ATOM   140  N  N   . GLY A 1 51  ? -7.958  7.332   29.593  1   20.972 ? 43   GLY A N   1 
ATOM   141  C  CA  . GLY A 1 51  ? -8.416  8.197   28.515  1   24.398 ? 43   GLY A CA  1 
ATOM   142  C  C   . GLY A 1 51  ? -7.689  7.916   27.197  1   26.542 ? 43   GLY A C   1 
ATOM   143  O  O   . GLY A 1 51  ? -8.131  8.375   26.145  1   28.069 ? 43   GLY A O   1 
ATOM   144  N  N   . GLY A 1 52  ? -6.583  7.152   27.26   1   25.64  ? 44   GLY A N   1 
ATOM   145  C  CA  . GLY A 1 52  ? -5.819  6.817   26.057  1   26.476 ? 44   GLY A CA  1 
ATOM   146  C  C   . GLY A 1 52  ? -6.644  5.91    25.137  1   23.914 ? 44   GLY A C   1 
ATOM   147  O  O   . GLY A 1 52  ? -7.421  5.109   25.624  1   23.668 ? 44   GLY A O   1 
ATOM   148  N  N   . ALA A 1 53  ? -6.508  6.083   23.816  1   22.106 ? 45   ALA A N   1 
ATOM   149  C  CA  . ALA A 1 53  ? -7.41   5.391   22.913  1   25.412 ? 45   ALA A CA  1 
ATOM   150  C  C   . ALA A 1 53  ? -6.655  4.572   21.869  1   23.913 ? 45   ALA A C   1 
ATOM   151  O  O   . ALA A 1 53  ? -7.239  4.198   20.868  1   26.882 ? 45   ALA A O   1 
ATOM   152  C  CB  . ALA A 1 53  ? -8.344  6.414   22.261  1   26.839 ? 45   ALA A CB  1 
ATOM   153  N  N   . GLN A 1 54  ? -5.368  4.294   22.072  1   22.586 ? 46   GLN A N   1 
ATOM   154  C  CA  . GLN A 1 54  ? -4.617  3.573   21.059  1   23.533 ? 46   GLN A CA  1 
ATOM   155  C  C   . GLN A 1 54  ? -4.758  2.063   21.318  1   23.108 ? 46   GLN A C   1 
ATOM   156  O  O   . GLN A 1 54  ? -4.28   1.586   22.35   1   20.735 ? 46   GLN A O   1 
ATOM   157  C  CB  . GLN A 1 54  ? -3.155  4.035   21.043  1   24.162 ? 46   GLN A CB  1 
ATOM   158  C  CG  . GLN A 1 54  ? -2.309  3.272   20.022  1   36.279 ? 46   GLN A CG  1 
ATOM   159  C  CD  . GLN A 1 54  ? -2.826  3.293   18.595  1   41.649 ? 46   GLN A CD  1 
ATOM   160  O  OE1 . GLN A 1 54  ? -3.258  4.336   18.078  1   38.492 ? 46   GLN A OE1 1 
ATOM   161  N  NE2 . GLN A 1 54  ? -2.784  2.129   17.945  1   31.809 ? 46   GLN A NE2 1 
ATOM   162  N  N   . PRO A 1 55  ? -5.375  1.265   20.404  1   21.627 ? 47   PRO A N   1 
ATOM   163  C  CA  . PRO A 1 55  ? -5.337  -0.19   20.507  1   18.568 ? 47   PRO A CA  1 
ATOM   164  C  C   . PRO A 1 55  ? -3.909  -0.707  20.422  1   18.957 ? 47   PRO A C   1 
ATOM   165  O  O   . PRO A 1 55  ? -3.149  -0.19   19.614  1   19.346 ? 47   PRO A O   1 
ATOM   166  C  CB  . PRO A 1 55  ? -6.164  -0.711  19.323  1   19.026 ? 47   PRO A CB  1 
ATOM   167  C  CG  . PRO A 1 55  ? -7.074  0.497   19.034  1   19.678 ? 47   PRO A CG  1 
ATOM   168  C  CD  . PRO A 1 55  ? -6.194  1.712   19.256  1   21.892 ? 47   PRO A CD  1 
ATOM   169  N  N   . ARG A 1 56  ? -3.588  -1.697  21.274  1   18.701 ? 48   ARG A N   1 
ATOM   170  C  CA  . ARG A 1 56  ? -2.259  -2.293  21.276  1   19.687 ? 48   ARG A CA  1 
ATOM   171  C  C   . ARG A 1 56  ? -2.353  -3.72   20.733  1   19.244 ? 48   ARG A C   1 
ATOM   172  O  O   . ARG A 1 56  ? -2.083  -3.949  19.557  1   20.541 ? 48   ARG A O   1 
ATOM   173  C  CB  . ARG A 1 56  ? -1.588  -2.147  22.643  1   20.078 ? 48   ARG A CB  1 
ATOM   174  C  CG  . ARG A 1 56  ? -1.505  -0.706  23.137  1   20.614 ? 48   ARG A CG  1 
ATOM   175  C  CD  . ARG A 1 56  ? -0.599  0.144   22.254  1   21.317 ? 48   ARG A CD  1 
ATOM   176  N  NE  . ARG A 1 56  ? -0.558  1.481   22.854  1   21.152 ? 48   ARG A NE  1 
ATOM   177  C  CZ  . ARG A 1 56  ? 0.147   2.497   22.361  1   24.528 ? 48   ARG A CZ  1 
ATOM   178  N  NH1 . ARG A 1 56  ? 0.912   2.324   21.281  1   22.055 ? 48   ARG A NH1 1 
ATOM   179  N  NH2 . ARG A 1 56  ? 0.09    3.69    22.956  1   23.67  ? 48   ARG A NH2 1 
ATOM   180  N  N   . ARG A 1 57  ? -2.85   -4.628  21.576  1   19.69  ? 49   ARG A N   1 
ATOM   181  C  CA  . ARG A 1 57  ? -3.366  -5.935  21.159  1   19.947 ? 49   ARG A CA  1 
ATOM   182  C  C   . ARG A 1 57  ? -2.245  -6.93   20.799  1   22.124 ? 49   ARG A C   1 
ATOM   183  O  O   . ARG A 1 57  ? -2.498  -7.965  20.17   1   22.219 ? 49   ARG A O   1 
ATOM   184  C  CB  . ARG A 1 57  ? -4.374  -5.836  20.009  1   20.255 ? 49   ARG A CB  1 
ATOM   185  C  CG  . ARG A 1 57  ? -5.459  -4.792  20.265  1   22.551 ? 49   ARG A CG  1 
ATOM   186  C  CD  . ARG A 1 57  ? -6.423  -4.699  19.118  1   19.33  ? 49   ARG A CD  1 
ATOM   187  N  NE  . ARG A 1 57  ? -5.797  -4.286  17.883  1   21.635 ? 49   ARG A NE  1 
ATOM   188  C  CZ  . ARG A 1 57  ? -6.004  -4.774  16.652  1   22.4   ? 49   ARG A CZ  1 
ATOM   189  N  NH1 . ARG A 1 57  ? -6.946  -5.702  16.397  1   20.614 ? 49   ARG A NH1 1 
ATOM   190  N  NH2 . ARG A 1 57  ? -5.213  -4.325  15.684  1   20.682 ? 49   ARG A NH2 1 
ATOM   191  N  N   A PHE A 1 58  ? -0.996  -6.643  21.159  0.5 22.14  ? 50   PHE A N   1 
ATOM   192  N  N   B PHE A 1 58  ? -1.01   -6.635  21.266  0.5 20.185 ? 50   PHE A N   1 
ATOM   193  C  CA  A PHE A 1 58  ? -0.021  -7.637  20.738  0.5 21.143 ? 50   PHE A CA  1 
ATOM   194  C  CA  B PHE A 1 58  ? 0.157   -7.488  21.03   0.5 19.035 ? 50   PHE A CA  1 
ATOM   195  C  C   A PHE A 1 58  ? 0.062   -8.729  21.793  0.5 20.264 ? 50   PHE A C   1 
ATOM   196  C  C   B PHE A 1 58  ? 0.047   -8.744  21.879  0.5 18.841 ? 50   PHE A C   1 
ATOM   197  O  O   A PHE A 1 58  ? -0.233  -8.533  22.976  0.5 20.633 ? 50   PHE A O   1 
ATOM   198  O  O   B PHE A 1 58  ? -0.313  -8.633  23.058  0.5 18.694 ? 50   PHE A O   1 
ATOM   199  C  CB  A PHE A 1 58  ? 1.286   -7.019  20.254  0.5 23.172 ? 50   PHE A CB  1 
ATOM   200  C  CB  B PHE A 1 58  ? 1.48    -6.789  21.407  0.5 15.839 ? 50   PHE A CB  1 
ATOM   201  C  CG  A PHE A 1 58  ? 1.627   -5.878  21.183  0.5 22.202 ? 50   PHE A CG  1 
ATOM   202  C  CG  B PHE A 1 58  ? 2.722   -7.629  21.109  0.5 15.68  ? 50   PHE A CG  1 
ATOM   203  C  CD1 A PHE A 1 58  ? 2.188   -6.116  22.421  0.5 23.524 ? 50   PHE A CD1 1 
ATOM   204  C  CD1 B PHE A 1 58  ? 3.107   -7.912  19.798  0.5 15.832 ? 50   PHE A CD1 1 
ATOM   205  C  CD2 A PHE A 1 58  ? 1.332   -4.572  20.832  0.5 21.536 ? 50   PHE A CD2 1 
ATOM   206  C  CD2 B PHE A 1 58  ? 3.49    -8.153  22.14   0.5 16.706 ? 50   PHE A CD2 1 
ATOM   207  C  CE1 A PHE A 1 58  ? 2.506   -5.03   23.236  0.5 21.024 ? 50   PHE A CE1 1 
ATOM   208  C  CE1 B PHE A 1 58  ? 4.23    -8.696  19.508  0.5 13.14  ? 50   PHE A CE1 1 
ATOM   209  C  CE2 A PHE A 1 58  ? 1.691   -3.508  21.637  0.5 20.057 ? 50   PHE A CE2 1 
ATOM   210  C  CE2 B PHE A 1 58  ? 4.629   -8.903  21.831  0.5 13.74  ? 50   PHE A CE2 1 
ATOM   211  C  CZ  A PHE A 1 58  ? 2.259   -3.725  22.838  0.5 15.194 ? 50   PHE A CZ  1 
ATOM   212  C  CZ  B PHE A 1 58  ? 4.924   -9.217  20.536  0.5 14.159 ? 50   PHE A CZ  1 
ATOM   213  N  N   . GLU A 1 59  ? 0.373   -9.92   21.287  1   18.601 ? 51   GLU A N   1 
ATOM   214  C  CA  . GLU A 1 59  ? 0.496   -11.13  22.072  1   16.984 ? 51   GLU A CA  1 
ATOM   215  C  C   . GLU A 1 59  ? 1.869   -11.702 21.773  1   17.936 ? 51   GLU A C   1 
ATOM   216  O  O   . GLU A 1 59  ? 2.148   -12.016 20.618  1   18.965 ? 51   GLU A O   1 
ATOM   217  C  CB  . GLU A 1 59  ? -0.592  -12.176 21.761  1   15.327 ? 51   GLU A CB  1 
ATOM   218  C  CG  . GLU A 1 59  ? -2      -11.587 21.958  1   18.283 ? 51   GLU A CG  1 
ATOM   219  C  CD  . GLU A 1 59  ? -3.004  -12.705 21.797  1   17.722 ? 51   GLU A CD  1 
ATOM   220  O  OE1 . GLU A 1 59  ? -3.346  -13.054 20.632  1   21.067 ? 51   GLU A OE1 1 
ATOM   221  O  OE2 . GLU A 1 59  ? -3.383  -13.249 22.831  1   17.469 ? 51   GLU A OE2 1 
ATOM   222  N  N   . GLY A 1 60  ? 2.706   -11.805 22.808  1   18.338 ? 52   GLY A N   1 
ATOM   223  C  CA  . GLY A 1 60  ? 4.044   -12.323 22.555  1   16.985 ? 52   GLY A CA  1 
ATOM   224  C  C   . GLY A 1 60  ? 4.966   -11.976 23.706  1   20.374 ? 52   GLY A C   1 
ATOM   225  O  O   . GLY A 1 60  ? 4.491   -11.718 24.807  1   19.759 ? 52   GLY A O   1 
ATOM   226  N  N   . THR A 1 61  ? 6.279   -12.043 23.418  1   20.697 ? 53   THR A N   1 
ATOM   227  C  CA  . THR A 1 61  ? 7.286   -12.06  24.47   1   19.452 ? 53   THR A CA  1 
ATOM   228  C  C   . THR A 1 61  ? 8.452   -11.149 24.096  1   18.645 ? 53   THR A C   1 
ATOM   229  O  O   . THR A 1 61  ? 8.709   -10.876 22.899  1   18.893 ? 53   THR A O   1 
ATOM   230  C  CB  . THR A 1 61  ? 7.807   -13.478 24.749  1   21.501 ? 53   THR A CB  1 
ATOM   231  O  OG1 . THR A 1 61  ? 8.39    -13.965 23.538  1   21.979 ? 53   THR A OG1 1 
ATOM   232  C  CG2 . THR A 1 61  ? 6.734   -14.413 25.285  1   21.536 ? 53   THR A CG2 1 
ATOM   233  N  N   . ILE A 1 62  ? 9.192   -10.788 25.15   1   18.638 ? 54   ILE A N   1 
ATOM   234  C  CA  . ILE A 1 62  ? 10.546  -10.258 25.024  1   21.009 ? 54   ILE A CA  1 
ATOM   235  C  C   . ILE A 1 62  ? 11.388  -10.972 26.08   1   20.566 ? 54   ILE A C   1 
ATOM   236  O  O   . ILE A 1 62  ? 11.051  -10.967 27.272  1   20.415 ? 54   ILE A O   1 
ATOM   237  C  CB  . ILE A 1 62  ? 10.606  -8.722  25.204  1   21.255 ? 54   ILE A CB  1 
ATOM   238  C  CG1 . ILE A 1 62  ? 9.746   -7.975  24.189  1   22.776 ? 54   ILE A CG1 1 
ATOM   239  C  CG2 . ILE A 1 62  ? 12.077  -8.233  25.127  1   19.197 ? 54   ILE A CG2 1 
ATOM   240  C  CD1 . ILE A 1 62  ? 9.422   -6.54   24.612  1   23.762 ? 54   ILE A CD1 1 
ATOM   241  N  N   . PHE A 1 63  ? 12.49   -11.564 25.613  1   17.937 ? 55   PHE A N   1 
ATOM   242  C  CA  . PHE A 1 63  ? 13.438  -12.22  26.491  1   21.353 ? 55   PHE A CA  1 
ATOM   243  C  C   . PHE A 1 63  ? 14.494  -11.179 26.888  1   20.18  ? 55   PHE A C   1 
ATOM   244  O  O   . PHE A 1 63  ? 15.076  -10.543 26.013  1   21.203 ? 55   PHE A O   1 
ATOM   245  C  CB  . PHE A 1 63  ? 14.028  -13.436 25.769  1   22.572 ? 55   PHE A CB  1 
ATOM   246  C  CG  . PHE A 1 63  ? 15.073  -14.169 26.616  1   23.378 ? 55   PHE A CG  1 
ATOM   247  C  CD1 . PHE A 1 63  ? 14.693  -15.146 27.556  1   24.482 ? 55   PHE A CD1 1 
ATOM   248  C  CD2 . PHE A 1 63  ? 16.433  -13.908 26.441  1   22.8   ? 55   PHE A CD2 1 
ATOM   249  C  CE1 . PHE A 1 63  ? 15.642  -15.842 28.316  1   27.32  ? 55   PHE A CE1 1 
ATOM   250  C  CE2 . PHE A 1 63  ? 17.376  -14.567 27.233  1   23.952 ? 55   PHE A CE2 1 
ATOM   251  C  CZ  . PHE A 1 63  ? 16.997  -15.515 28.182  1   24.467 ? 55   PHE A CZ  1 
ATOM   252  N  N   . ASP A 1 64  ? 14.706  -11.032 28.2    1   20.326 ? 56   ASP A N   1 
ATOM   253  C  CA  . ASP A 1 64  ? 15.736  -10.134 28.723  1   22.051 ? 56   ASP A CA  1 
ATOM   254  C  C   . ASP A 1 64  ? 15.442  -8.692  28.301  1   18.709 ? 56   ASP A C   1 
ATOM   255  O  O   . ASP A 1 64  ? 16.184  -8.046  27.528  1   20.314 ? 56   ASP A O   1 
ATOM   256  C  CB  . ASP A 1 64  ? 17.11   -10.626 28.288  1   23.027 ? 56   ASP A CB  1 
ATOM   257  C  CG  . ASP A 1 64  ? 18.247  -10.19  29.193  1   25.775 ? 56   ASP A CG  1 
ATOM   258  O  OD1 . ASP A 1 64  ? 17.96   -9.59   30.236  1   24.461 ? 56   ASP A OD1 1 
ATOM   259  O  OD2 . ASP A 1 64  ? 19.401  -10.439 28.817  1   26.083 ? 56   ASP A OD2 1 
ATOM   260  N  N   . VAL A 1 65  ? 14.298  -8.213  28.789  1   18.682 ? 57   VAL A N   1 
ATOM   261  C  CA  . VAL A 1 65  ? 13.829  -6.865  28.513  1   17.931 ? 57   VAL A CA  1 
ATOM   262  C  C   . VAL A 1 65  ? 14.905  -5.856  28.914  1   19.804 ? 57   VAL A C   1 
ATOM   263  O  O   . VAL A 1 65  ? 15.535  -6.021  29.953  1   21.555 ? 57   VAL A O   1 
ATOM   264  C  CB  . VAL A 1 65  ? 12.518  -6.582  29.268  1   20.194 ? 57   VAL A CB  1 
ATOM   265  C  CG1 . VAL A 1 65  ? 11.968  -5.188  28.929  1   19.123 ? 57   VAL A CG1 1 
ATOM   266  C  CG2 . VAL A 1 65  ? 11.481  -7.677  29.014  1   18.921 ? 57   VAL A CG2 1 
ATOM   267  N  N   . MET A 1 66  ? 15.08   -4.831  28.077  1   20.97  ? 58   MET A N   1 
ATOM   268  C  CA  . MET A 1 66  ? 16.068  -3.798  28.353  1   23.214 ? 58   MET A CA  1 
ATOM   269  C  C   . MET A 1 66  ? 15.795  -3.151  29.708  1   22.42  ? 58   MET A C   1 
ATOM   270  O  O   . MET A 1 66  ? 14.643  -2.874  30.035  1   24.496 ? 58   MET A O   1 
ATOM   271  C  CB  . MET A 1 66  ? 16.01   -2.707  27.286  1   26.339 ? 58   MET A CB  1 
ATOM   272  C  CG  . MET A 1 66  ? 17.118  -1.685  27.464  1   33.28  ? 58   MET A CG  1 
ATOM   273  S  SD  . MET A 1 66  ? 17.113  -0.495  26.103  1   46.678 ? 58   MET A SD  1 
ATOM   274  C  CE  . MET A 1 66  ? 16.581  -1.632  24.8    1   31.096 ? 58   MET A CE  1 
ATOM   275  N  N   . THR A 1 67  ? 16.849  -2.976  30.534  1   22.377 ? 59   THR A N   1 
ATOM   276  C  CA  . THR A 1 67  ? 16.656  -2.342  31.837  1   21.249 ? 59   THR A CA  1 
ATOM   277  C  C   . THR A 1 67  ? 17.675  -1.199  31.956  1   27.827 ? 59   THR A C   1 
ATOM   278  O  O   . THR A 1 67  ? 18.752  -1.283  31.367  1   28.512 ? 59   THR A O   1 
ATOM   279  C  CB  . THR A 1 67  ? 16.764  -3.328  32.998  1   23.898 ? 59   THR A CB  1 
ATOM   280  O  OG1 . THR A 1 67  ? 18.1    -3.826  32.931  1   31.433 ? 59   THR A OG1 1 
ATOM   281  C  CG2 . THR A 1 67  ? 15.778  -4.484  32.894  1   25.21  ? 59   THR A CG2 1 
ATOM   282  N  N   . ARG A 1 68  ? 17.3    -0.144  32.677  1   24.053 ? 60   ARG A N   1 
ATOM   283  C  CA  . ARG A 1 68  ? 18.206  0.95    33.005  1   22.943 ? 60   ARG A CA  1 
ATOM   284  C  C   . ARG A 1 68  ? 18.394  0.888   34.519  1   27.621 ? 60   ARG A C   1 
ATOM   285  O  O   . ARG A 1 68  ? 17.417  0.699   35.225  1   26.722 ? 60   ARG A O   1 
ATOM   286  C  CB  . ARG A 1 68  ? 17.638  2.283   32.499  1   25.238 ? 60   ARG A CB  1 
ATOM   287  C  CG  . ARG A 1 68  ? 17.413  2.41    30.996  1   30.529 ? 60   ARG A CG  1 
ATOM   288  C  CD  . ARG A 1 68  ? 17.062  3.876   30.659  1   34.814 ? 60   ARG A CD  1 
ATOM   289  N  NE  . ARG A 1 68  ? 15.957  4.544   31.371  1   35.256 ? 60   ARG A NE  1 
ATOM   290  C  CZ  . ARG A 1 68  ? 14.632  4.405   31.167  1   38.102 ? 60   ARG A CZ  1 
ATOM   291  N  NH1 . ARG A 1 68  ? 14.194  3.552   30.231  1   35.925 ? 60   ARG A NH1 1 
ATOM   292  N  NH2 . ARG A 1 68  ? 13.767  5.131   31.885  1   27.936 ? 60   ARG A NH2 1 
ATOM   293  N  N   . GLY A 1 69  ? 19.653  0.955   34.993  1   26.892 ? 61   GLY A N   1 
ATOM   294  C  CA  . GLY A 1 69  ? 19.951  0.855   36.419  1   29.884 ? 61   GLY A CA  1 
ATOM   295  C  C   . GLY A 1 69  ? 20.031  -0.61   36.825  1   28.49  ? 61   GLY A C   1 
ATOM   296  O  O   . GLY A 1 69  ? 20.14   -1.485  35.957  1   35.944 ? 61   GLY A O   1 
ATOM   297  N  N   . THR A 1 70  ? 19.998  -0.902  38.127  1   30.394 ? 62   THR A N   1 
ATOM   298  C  CA  . THR A 1 70  ? 20.232  -2.278  38.561  1   31.252 ? 62   THR A CA  1 
ATOM   299  C  C   . THR A 1 70  ? 18.926  -2.896  39.064  1   28.875 ? 62   THR A C   1 
ATOM   300  O  O   . THR A 1 70  ? 18.354  -2.392  40.035  1   31.357 ? 62   THR A O   1 
ATOM   301  C  CB  . THR A 1 70  ? 21.305  -2.319  39.651  1   33.365 ? 62   THR A CB  1 
ATOM   302  O  OG1 . THR A 1 70  ? 22.488  -1.934  38.974  1   40.188 ? 62   THR A OG1 1 
ATOM   303  C  CG2 . THR A 1 70  ? 21.598  -3.723  40.125  1   27.373 ? 62   THR A CG2 1 
ATOM   304  N  N   . ILE A 1 71  ? 18.534  -4.031  38.47   1   27.557 ? 63   ILE A N   1 
ATOM   305  C  CA  . ILE A 1 71  ? 17.373  -4.767  38.971  1   25.746 ? 63   ILE A CA  1 
ATOM   306  C  C   . ILE A 1 71  ? 17.733  -5.411  40.317  1   26.279 ? 63   ILE A C   1 
ATOM   307  O  O   . ILE A 1 71  ? 18.645  -6.236  40.35   1   26.998 ? 63   ILE A O   1 
ATOM   308  C  CB  . ILE A 1 71  ? 16.889  -5.801  37.943  1   26.652 ? 63   ILE A CB  1 
ATOM   309  C  CG1 . ILE A 1 71  ? 16.451  -5.109  36.62   1   29.649 ? 63   ILE A CG1 1 
ATOM   310  C  CG2 . ILE A 1 71  ? 15.813  -6.739  38.533  1   24.694 ? 63   ILE A CG2 1 
ATOM   311  C  CD1 . ILE A 1 71  ? 15.287  -4.133  36.756  1   27.482 ? 63   ILE A CD1 1 
ATOM   312  N  N   . PRO A 1 72  ? 17.002  -5.109  41.422  1   24.655 ? 64   PRO A N   1 
ATOM   313  C  CA  . PRO A 1 72  ? 17.263  -5.759  42.704  1   26.872 ? 64   PRO A CA  1 
ATOM   314  C  C   . PRO A 1 72  ? 17.268  -7.278  42.587  1   30.241 ? 64   PRO A C   1 
ATOM   315  O  O   . PRO A 1 72  ? 16.331  -7.854  42.029  1   28.156 ? 64   PRO A O   1 
ATOM   316  C  CB  . PRO A 1 72  ? 16.131  -5.278  43.611  1   26.677 ? 64   PRO A CB  1 
ATOM   317  C  CG  . PRO A 1 72  ? 15.849  -3.894  43.029  1   27.729 ? 64   PRO A CG  1 
ATOM   318  C  CD  . PRO A 1 72  ? 15.924  -4.11   41.52   1   24.506 ? 64   PRO A CD  1 
ATOM   319  N  N   . LYS A 1 73  ? 18.338  -7.912  43.094  1   28.986 ? 65   LYS A N   1 
ATOM   320  C  CA  . LYS A 1 73  ? 18.386  -9.37   43.142  1   33.381 ? 65   LYS A CA  1 
ATOM   321  C  C   . LYS A 1 73  ? 17.326  -9.955  44.074  1   26.333 ? 65   LYS A C   1 
ATOM   322  O  O   . LYS A 1 73  ? 16.984  -11.126 43.935  1   29.379 ? 65   LYS A O   1 
ATOM   323  C  CB  . LYS A 1 73  ? 19.753  -9.929  43.568  1   37.561 ? 65   LYS A CB  1 
ATOM   324  C  CG  . LYS A 1 73  ? 20.839  -9.79   42.493  1   48.755 ? 65   LYS A CG  1 
ATOM   325  C  CD  . LYS A 1 73  ? 20.638  -10.535 41.173  1   50.151 ? 65   LYS A CD  1 
ATOM   326  C  CE  . LYS A 1 73  ? 21.585  -10.143 40.095  1   56.967 ? 65   LYS A CE  1 
ATOM   327  N  NZ  . LYS A 1 73  ? 22.913  -10.692 40.347  1   55.761 ? 65   LYS A NZ  1 
ATOM   328  N  N   . GLU A 1 74  ? 16.781  -9.148  44.977  1   26.313 ? 66   GLU A N   1 
ATOM   329  C  CA  . GLU A 1 74  ? 15.748  -9.595  45.903  1   26.019 ? 66   GLU A CA  1 
ATOM   330  C  C   . GLU A 1 74  ? 14.414  -9.842  45.181  1   25.495 ? 66   GLU A C   1 
ATOM   331  O  O   . GLU A 1 74  ? 13.547  -10.522 45.729  1   26.284 ? 66   GLU A O   1 
ATOM   332  C  CB  . GLU A 1 74  ? 15.46   -8.555  46.983  1   28.448 ? 66   GLU A CB  1 
ATOM   333  C  CG  . GLU A 1 74  ? 16.652  -8.335  47.918  1   30.977 ? 66   GLU A CG  1 
ATOM   334  C  CD  . GLU A 1 74  ? 17.655  -7.31   47.427  1   36.239 ? 66   GLU A CD  1 
ATOM   335  O  OE1 . GLU A 1 74  ? 17.715  -6.864  46.245  1   31.526 ? 66   GLU A OE1 1 
ATOM   336  O  OE2 . GLU A 1 74  ? 18.418  -6.936  48.338  1   39.478 ? 66   GLU A OE2 1 
ATOM   337  N  N   . LEU A 1 75  ? 14.249  -9.323  43.955  1   25.088 ? 67   LEU A N   1 
ATOM   338  C  CA  . LEU A 1 75  ? 13.002  -9.561  43.228  1   24.387 ? 67   LEU A CA  1 
ATOM   339  C  C   . LEU A 1 75  ? 13.024  -10.974 42.654  1   26.457 ? 67   LEU A C   1 
ATOM   340  O  O   . LEU A 1 75  ? 13.88   -11.314 41.851  1   27.784 ? 67   LEU A O   1 
ATOM   341  C  CB  . LEU A 1 75  ? 12.783  -8.501  42.139  1   27.293 ? 67   LEU A CB  1 
ATOM   342  C  CG  . LEU A 1 75  ? 12.437  -7.1    42.65   1   27.298 ? 67   LEU A CG  1 
ATOM   343  C  CD1 . LEU A 1 75  ? 12.493  -6.123  41.478  1   26.956 ? 67   LEU A CD1 1 
ATOM   344  C  CD2 . LEU A 1 75  ? 11.084  -7.029  43.318  1   26.669 ? 67   LEU A CD2 1 
ATOM   345  N  N   . HIS A 1 76  ? 12.057  -11.79  43.085  1   23.482 ? 68   HIS A N   1 
ATOM   346  C  CA  . HIS A 1 76  ? 11.973  -13.194 42.706  1   23.427 ? 68   HIS A CA  1 
ATOM   347  C  C   . HIS A 1 76  ? 10.497  -13.526 42.535  1   24.248 ? 68   HIS A C   1 
ATOM   348  O  O   . HIS A 1 76  ? 9.817   -13.952 43.466  1   24.003 ? 68   HIS A O   1 
ATOM   349  C  CB  . HIS A 1 76  ? 12.667  -14.049 43.789  1   25.089 ? 68   HIS A CB  1 
ATOM   350  C  CG  . HIS A 1 76  ? 12.824  -15.485 43.386  1   27.37  ? 68   HIS A CG  1 
ATOM   351  N  ND1 . HIS A 1 76  ? 13.822  -15.903 42.536  1   28.629 ? 68   HIS A ND1 1 
ATOM   352  C  CD2 . HIS A 1 76  ? 12.099  -16.57  43.694  1   26.635 ? 68   HIS A CD2 1 
ATOM   353  C  CE1 . HIS A 1 76  ? 13.734  -17.219 42.361  1   28.478 ? 68   HIS A CE1 1 
ATOM   354  N  NE2 . HIS A 1 76  ? 12.705  -17.636 43.065  1   28.956 ? 68   HIS A NE2 1 
ATOM   355  N  N   . GLY A 1 77  ? 9.979   -13.283 41.33   1   22.48  ? 69   GLY A N   1 
ATOM   356  C  CA  . GLY A 1 77  ? 8.534   -13.378 41.162  1   19.453 ? 69   GLY A CA  1 
ATOM   357  C  C   . GLY A 1 77  ? 8.129   -12.673 39.863  1   22.003 ? 69   GLY A C   1 
ATOM   358  O  O   . GLY A 1 77  ? 8.971   -12.398 39.002  1   19.899 ? 69   GLY A O   1 
ATOM   359  N  N   . THR A 1 78  ? 6.822   -12.409 39.735  1   20.252 ? 70   THR A N   1 
ATOM   360  C  CA  . THR A 1 78  ? 6.288   -11.887 38.488  1   20.514 ? 70   THR A CA  1 
ATOM   361  C  C   . THR A 1 78  ? 5.327   -10.763 38.855  1   20.727 ? 70   THR A C   1 
ATOM   362  O  O   . THR A 1 78  ? 4.486   -10.925 39.749  1   22.807 ? 70   THR A O   1 
ATOM   363  C  CB  . THR A 1 78  ? 5.532   -12.975 37.726  1   18.806 ? 70   THR A CB  1 
ATOM   364  O  OG1 . THR A 1 78  ? 6.305   -14.173 37.625  1   21.102 ? 70   THR A OG1 1 
ATOM   365  C  CG2 . THR A 1 78  ? 5.267   -12.595 36.27   1   17.083 ? 70   THR A CG2 1 
ATOM   366  N  N   . PHE A 1 79  ? 5.471   -9.645  38.154  1   18.915 ? 71   PHE A N   1 
ATOM   367  C  CA  . PHE A 1 79  ? 4.493   -8.579  38.216  1   19.887 ? 71   PHE A CA  1 
ATOM   368  C  C   . PHE A 1 79  ? 3.556   -8.846  37.043  1   18.979 ? 71   PHE A C   1 
ATOM   369  O  O   . PHE A 1 79  ? 3.977   -8.733  35.898  1   20.763 ? 71   PHE A O   1 
ATOM   370  C  CB  . PHE A 1 79  ? 5.215   -7.242  38.057  1   17.612 ? 71   PHE A CB  1 
ATOM   371  C  CG  . PHE A 1 79  ? 4.365   -5.963  38.02   1   19.798 ? 71   PHE A CG  1 
ATOM   372  C  CD1 . PHE A 1 79  ? 3.057   -5.901  38.529  1   18.984 ? 71   PHE A CD1 1 
ATOM   373  C  CD2 . PHE A 1 79  ? 4.943   -4.77   37.545  1   20.788 ? 71   PHE A CD2 1 
ATOM   374  C  CE1 . PHE A 1 79  ? 2.34    -4.684  38.531  1   22.481 ? 71   PHE A CE1 1 
ATOM   375  C  CE2 . PHE A 1 79  ? 4.242   -3.559  37.549  1   23.331 ? 71   PHE A CE2 1 
ATOM   376  C  CZ  . PHE A 1 79  ? 2.936   -3.52   38.047  1   23.273 ? 71   PHE A CZ  1 
ATOM   377  N  N   . TYR A 1 80  ? 2.315   -9.228  37.358  1   20.1   ? 72   TYR A N   1 
ATOM   378  C  CA  . TYR A 1 80  ? 1.326   -9.456  36.315  1   18.343 ? 72   TYR A CA  1 
ATOM   379  C  C   . TYR A 1 80  ? 0.393   -8.25   36.335  1   20.431 ? 72   TYR A C   1 
ATOM   380  O  O   . TYR A 1 80  ? -0.096  -7.877  37.409  1   22.539 ? 72   TYR A O   1 
ATOM   381  C  CB  . TYR A 1 80  ? 0.447   -10.684 36.588  1   19.189 ? 72   TYR A CB  1 
ATOM   382  C  CG  . TYR A 1 80  ? 1.148   -12.036 36.506  1   20.27  ? 72   TYR A CG  1 
ATOM   383  C  CD1 . TYR A 1 80  ? 1.261   -12.715 35.296  1   19.772 ? 72   TYR A CD1 1 
ATOM   384  C  CD2 . TYR A 1 80  ? 1.643   -12.659 37.662  1   19.967 ? 72   TYR A CD2 1 
ATOM   385  C  CE1 . TYR A 1 80  ? 1.846   -13.983 35.24   1   20.228 ? 72   TYR A CE1 1 
ATOM   386  C  CE2 . TYR A 1 80  ? 2.286   -13.892 37.585  1   20.553 ? 72   TYR A CE2 1 
ATOM   387  C  CZ  . TYR A 1 80  ? 2.388   -14.56  36.379  1   19.398 ? 72   TYR A CZ  1 
ATOM   388  O  OH  . TYR A 1 80  ? 2.966   -15.819 36.31   1   21.793 ? 72   TYR A OH  1 
ATOM   389  N  N   . ARG A 1 81  ? 0.134   -7.673  35.148  1   19.671 ? 73   ARG A N   1 
ATOM   390  C  CA  . ARG A 1 81  ? -0.838  -6.592  35.082  1   19.259 ? 73   ARG A CA  1 
ATOM   391  C  C   . ARG A 1 81  ? -1.877  -6.902  34.015  1   19.851 ? 73   ARG A C   1 
ATOM   392  O  O   . ARG A 1 81  ? -1.562  -7.607  33.065  1   22.11  ? 73   ARG A O   1 
ATOM   393  C  CB  . ARG A 1 81  ? 0.036   -5.462  34.534  1   26.916 ? 73   ARG A CB  1 
ATOM   394  C  CG  . ARG A 1 81  ? -0.451  -4.04   34.649  1   36.164 ? 73   ARG A CG  1 
ATOM   395  C  CD  . ARG A 1 81  ? -0.065  -3.345  35.934  1   25.897 ? 73   ARG A CD  1 
ATOM   396  N  NE  . ARG A 1 81  ? -0.721  -2.112  35.507  1   24.76  ? 73   ARG A NE  1 
ATOM   397  C  CZ  . ARG A 1 81  ? -1.807  -1.62   36.057  1   21.493 ? 73   ARG A CZ  1 
ATOM   398  N  NH1 . ARG A 1 81  ? -2.193  -2.004  37.275  1   17.257 ? 73   ARG A NH1 1 
ATOM   399  N  NH2 . ARG A 1 81  ? -2.462  -0.694  35.381  1   20.211 ? 73   ARG A NH2 1 
ATOM   400  N  N   . ILE A 1 82  ? -3.119  -6.404  34.213  1   18.268 ? 74   ILE A N   1 
ATOM   401  C  CA  . ILE A 1 82  ? -4.165  -6.734  33.267  1   17.545 ? 74   ILE A CA  1 
ATOM   402  C  C   . ILE A 1 82  ? -4.757  -5.416  32.763  1   18.263 ? 74   ILE A C   1 
ATOM   403  O  O   . ILE A 1 82  ? -4.841  -4.442  33.503  1   19.185 ? 74   ILE A O   1 
ATOM   404  C  CB  . ILE A 1 82  ? -5.21   -7.701  33.881  1   16.613 ? 74   ILE A CB  1 
ATOM   405  C  CG1 . ILE A 1 82  ? -6.141  -8.321  32.823  1   17.167 ? 74   ILE A CG1 1 
ATOM   406  C  CG2 . ILE A 1 82  ? -6.021  -7.054  35.026  1   19.125 ? 74   ILE A CG2 1 
ATOM   407  C  CD1 . ILE A 1 82  ? -6.924  -9.503  33.389  1   18.459 ? 74   ILE A CD1 1 
ATOM   408  N  N   . MET A 1 83  ? -5.104  -5.423  31.473  1   17.354 ? 75   MET A N   1 
ATOM   409  C  CA  . MET A 1 83  ? -5.544  -4.21   30.802  1   19.164 ? 75   MET A CA  1 
ATOM   410  C  C   . MET A 1 83  ? -6.76   -4.536  29.938  1   18.608 ? 75   MET A C   1 
ATOM   411  O  O   . MET A 1 83  ? -6.887  -5.652  29.44   1   19.305 ? 75   MET A O   1 
ATOM   412  C  CB  . MET A 1 83  ? -4.467  -3.781  29.8    1   18.254 ? 75   MET A CB  1 
ATOM   413  C  CG  . MET A 1 83  ? -3.215  -3.233  30.496  1   19.994 ? 75   MET A CG  1 
ATOM   414  S  SD  . MET A 1 83  ? -1.674  -3.713  29.664  1   22.531 ? 75   MET A SD  1 
ATOM   415  C  CE  . MET A 1 83  ? -1.654  -5.434  30.212  1   20.182 ? 75   MET A CE  1 
ATOM   416  N  N   . PRO A 1 84  ? -7.643  -3.546  29.709  1   18.994 ? 76   PRO A N   1 
ATOM   417  C  CA  . PRO A 1 84  ? -8.668  -3.689  28.686  1   19.156 ? 76   PRO A CA  1 
ATOM   418  C  C   . PRO A 1 84  ? -8.078  -3.295  27.344  1   18.775 ? 76   PRO A C   1 
ATOM   419  O  O   . PRO A 1 84  ? -7.505  -2.227  27.233  1   19.361 ? 76   PRO A O   1 
ATOM   420  C  CB  . PRO A 1 84  ? -9.767  -2.727  29.183  1   19.938 ? 76   PRO A CB  1 
ATOM   421  C  CG  . PRO A 1 84  ? -8.928  -1.553  29.808  1   18.751 ? 76   PRO A CG  1 
ATOM   422  C  CD  . PRO A 1 84  ? -7.678  -2.239  30.409  1   18.464 ? 76   PRO A CD  1 
ATOM   423  N  N   . ASP A 1 85  ? -8.203  -4.169  26.338  1   17.083 ? 77   ASP A N   1 
ATOM   424  C  CA  . ASP A 1 85  ? -7.642  -3.821  25.041  1   16.457 ? 77   ASP A CA  1 
ATOM   425  C  C   . ASP A 1 85  ? -8.523  -4.523  24.018  1   18.36  ? 77   ASP A C   1 
ATOM   426  O  O   . ASP A 1 85  ? -8.169  -5.59   23.546  1   21.865 ? 77   ASP A O   1 
ATOM   427  C  CB  . ASP A 1 85  ? -6.219  -4.353  24.935  1   17.948 ? 77   ASP A CB  1 
ATOM   428  C  CG  . ASP A 1 85  ? -5.25   -3.707  23.955  1   20.799 ? 77   ASP A CG  1 
ATOM   429  O  OD1 . ASP A 1 85  ? -5.656  -2.776  23.208  1   18.834 ? 77   ASP A OD1 1 
ATOM   430  O  OD2 . ASP A 1 85  ? -4.051  -4.086  24.008  1   22.001 ? 77   ASP A OD2 1 
ATOM   431  N  N   . TYR A 1 86  ? -9.643  -3.894  23.667  1   17.821 ? 78   TYR A N   1 
ATOM   432  C  CA  . TYR A 1 86  ? -10.541 -4.521  22.709  1   18.756 ? 78   TYR A CA  1 
ATOM   433  C  C   . TYR A 1 86  ? -9.765  -5.132  21.547  1   19.258 ? 78   TYR A C   1 
ATOM   434  O  O   . TYR A 1 86  ? -8.993  -4.447  20.907  1   21.068 ? 78   TYR A O   1 
ATOM   435  C  CB  . TYR A 1 86  ? -11.462 -3.451  22.138  1   20.208 ? 78   TYR A CB  1 
ATOM   436  C  CG  . TYR A 1 86  ? -12.823 -3.345  22.812  1   19.45  ? 78   TYR A CG  1 
ATOM   437  C  CD1 . TYR A 1 86  ? -13.688 -4.441  22.836  1   20.534 ? 78   TYR A CD1 1 
ATOM   438  C  CD2 . TYR A 1 86  ? -13.226 -2.143  23.398  1   18.762 ? 78   TYR A CD2 1 
ATOM   439  C  CE1 . TYR A 1 86  ? -14.978 -4.309  23.371  1   21.18  ? 78   TYR A CE1 1 
ATOM   440  C  CE2 . TYR A 1 86  ? -14.503 -2.017  23.954  1   21.066 ? 78   TYR A CE2 1 
ATOM   441  C  CZ  . TYR A 1 86  ? -15.373 -3.099  23.913  1   20.234 ? 78   TYR A CZ  1 
ATOM   442  O  OH  . TYR A 1 86  ? -16.665 -2.948  24.351  1   22.382 ? 78   TYR A OH  1 
ATOM   443  N  N   . ALA A 1 87  ? -9.951  -6.45   21.344  1   19.253 ? 79   ALA A N   1 
ATOM   444  C  CA  . ALA A 1 87  ? -9.204  -7.2    20.362  1   17.236 ? 79   ALA A CA  1 
ATOM   445  C  C   . ALA A 1 87  ? -9.732  -6.941  18.958  1   18.084 ? 79   ALA A C   1 
ATOM   446  O  O   . ALA A 1 87  ? -8.955  -7.013  18.023  1   19.663 ? 79   ALA A O   1 
ATOM   447  C  CB  . ALA A 1 87  ? -9.234  -8.693  20.705  1   17.541 ? 79   ALA A CB  1 
ATOM   448  N  N   . GLN A 1 88  ? -11.056 -6.764  18.837  1   21.271 ? 80   GLN A N   1 
ATOM   449  C  CA  . GLN A 1 88  ? -11.7   -6.403  17.584  1   22.795 ? 80   GLN A CA  1 
ATOM   450  C  C   . GLN A 1 88  ? -12.318 -5.007  17.755  1   21.545 ? 80   GLN A C   1 
ATOM   451  O  O   . GLN A 1 88  ? -12.724 -4.659  18.873  1   21.543 ? 80   GLN A O   1 
ATOM   452  C  CB  . GLN A 1 88  ? -12.794 -7.42   17.217  1   21.606 ? 80   GLN A CB  1 
ATOM   453  C  CG  . GLN A 1 88  ? -12.287 -8.821  16.854  1   19.731 ? 80   GLN A CG  1 
ATOM   454  C  CD  . GLN A 1 88  ? -11.272 -8.859  15.717  1   22.252 ? 80   GLN A CD  1 
ATOM   455  O  OE1 . GLN A 1 88  ? -10.202 -9.456  15.854  1   20.964 ? 80   GLN A OE1 1 
ATOM   456  N  NE2 . GLN A 1 88  ? -11.551 -8.219  14.585  1   20.595 ? 80   GLN A NE2 1 
ATOM   457  N  N   . PRO A 1 89  ? -12.453 -4.189  16.687  1   19.396 ? 81   PRO A N   1 
ATOM   458  C  CA  . PRO A 1 89  ? -13.163 -2.907  16.801  1   20.514 ? 81   PRO A CA  1 
ATOM   459  C  C   . PRO A 1 89  ? -14.611 -3.14   17.245  1   21.9   ? 81   PRO A C   1 
ATOM   460  O  O   . PRO A 1 89  ? -15.3   -3.961  16.63   1   21.699 ? 81   PRO A O   1 
ATOM   461  C  CB  . PRO A 1 89  ? -13.081 -2.261  15.415  1   22.021 ? 81   PRO A CB  1 
ATOM   462  C  CG  . PRO A 1 89  ? -12.615 -3.355  14.515  1   21.442 ? 81   PRO A CG  1 
ATOM   463  C  CD  . PRO A 1 89  ? -12.016 -4.477  15.307  1   19.946 ? 81   PRO A CD  1 
ATOM   464  N  N   . PRO A 1 90  ? -15.03  -2.587  18.407  1   22.001 ? 82   PRO A N   1 
ATOM   465  C  CA  . PRO A 1 90  ? -16.258 -3.044  19.058  1   20.72  ? 82   PRO A CA  1 
ATOM   466  C  C   . PRO A 1 90  ? -17.546 -2.478  18.451  1   22.239 ? 82   PRO A C   1 
ATOM   467  O  O   . PRO A 1 90  ? -18.319 -1.852  19.158  1   22.703 ? 82   PRO A O   1 
ATOM   468  C  CB  . PRO A 1 90  ? -15.997 -2.666  20.536  1   19.566 ? 82   PRO A CB  1 
ATOM   469  C  CG  . PRO A 1 90  ? -15.19  -1.384  20.39   1   19.177 ? 82   PRO A CG  1 
ATOM   470  C  CD  . PRO A 1 90  ? -14.216 -1.702  19.287  1   19.167 ? 82   PRO A CD  1 
ATOM   471  N  N   . THR A 1 91  ? -17.755 -2.71   17.149  1   21.41  ? 83   THR A N   1 
ATOM   472  C  CA  . THR A 1 91  ? -18.728 -1.925  16.39   1   21.799 ? 83   THR A CA  1 
ATOM   473  C  C   . THR A 1 91  ? -20.118 -2.571  16.367  1   21.637 ? 83   THR A C   1 
ATOM   474  O  O   . THR A 1 91  ? -20.992 -2.007  15.718  1   22.973 ? 83   THR A O   1 
ATOM   475  C  CB  . THR A 1 91  ? -18.244 -1.727  14.936  1   22.273 ? 83   THR A CB  1 
ATOM   476  O  OG1 . THR A 1 91  ? -17.98  -3.051  14.51   1   23.922 ? 83   THR A OG1 1 
ATOM   477  C  CG2 . THR A 1 91  ? -16.989 -0.904  14.831  1   27.058 ? 83   THR A CG2 1 
ATOM   478  N  N   . TYR A 1 92  ? -20.35  -3.668  17.104  1   20.112 ? 84   TYR A N   1 
ATOM   479  C  CA  . TYR A 1 92  ? -21.633 -4.382  17.049  1   20.479 ? 84   TYR A CA  1 
ATOM   480  C  C   . TYR A 1 92  ? -22.831 -3.433  17.305  1   24.209 ? 84   TYR A C   1 
ATOM   481  O  O   . TYR A 1 92  ? -23.823 -3.431  16.551  1   22.444 ? 84   TYR A O   1 
ATOM   482  C  CB  . TYR A 1 92  ? -21.647 -5.639  17.938  1   22.107 ? 84   TYR A CB  1 
ATOM   483  C  CG  . TYR A 1 92  ? -23.039 -6.257  17.887  1   21.677 ? 84   TYR A CG  1 
ATOM   484  C  CD1 . TYR A 1 92  ? -23.486 -6.876  16.713  1   22.324 ? 84   TYR A CD1 1 
ATOM   485  C  CD2 . TYR A 1 92  ? -23.912 -6.107  18.962  1   20.158 ? 84   TYR A CD2 1 
ATOM   486  C  CE1 . TYR A 1 92  ? -24.786 -7.364  16.639  1   23.556 ? 84   TYR A CE1 1 
ATOM   487  C  CE2 . TYR A 1 92  ? -25.241 -6.512  18.861  1   25.399 ? 84   TYR A CE2 1 
ATOM   488  C  CZ  . TYR A 1 92  ? -25.659 -7.148  17.698  1   23.766 ? 84   TYR A CZ  1 
ATOM   489  O  OH  . TYR A 1 92  ? -26.934 -7.606  17.583  1   24.81  ? 84   TYR A OH  1 
ATOM   490  N  N   . TYR A 1 93  ? -22.801 -2.737  18.444  1   22.121 ? 85   TYR A N   1 
ATOM   491  C  CA  . TYR A 1 93  ? -23.953 -1.989  18.923  1   22.179 ? 85   TYR A CA  1 
ATOM   492  C  C   . TYR A 1 93  ? -23.711 -0.496  18.776  1   23.35  ? 85   TYR A C   1 
ATOM   493  O  O   . TYR A 1 93  ? -22.75  0.032   19.36   1   21.54  ? 85   TYR A O   1 
ATOM   494  C  CB  . TYR A 1 93  ? -24.233 -2.324  20.395  1   21.715 ? 85   TYR A CB  1 
ATOM   495  C  CG  . TYR A 1 93  ? -25.531 -1.715  20.92   1   23.152 ? 85   TYR A CG  1 
ATOM   496  C  CD1 . TYR A 1 93  ? -26.768 -2.189  20.467  1   28.706 ? 85   TYR A CD1 1 
ATOM   497  C  CD2 . TYR A 1 93  ? -25.522 -0.686  21.861  1   26.009 ? 85   TYR A CD2 1 
ATOM   498  C  CE1 . TYR A 1 93  ? -27.963 -1.651  20.93   1   29.551 ? 85   TYR A CE1 1 
ATOM   499  C  CE2 . TYR A 1 93  ? -26.709 -0.156  22.361  1   28.132 ? 85   TYR A CE2 1 
ATOM   500  C  CZ  . TYR A 1 93  ? -27.922 -0.633  21.872  1   29.179 ? 85   TYR A CZ  1 
ATOM   501  O  OH  . TYR A 1 93  ? -29.101 -0.142  22.368  1   30.836 ? 85   TYR A OH  1 
ATOM   502  N  N   . LYS A 1 94  ? -24.579 0.17    17.99   1   23.135 ? 86   LYS A N   1 
ATOM   503  C  CA  . LYS A 1 94  ? -24.475 1.62    17.767  1   24.256 ? 86   LYS A CA  1 
ATOM   504  C  C   . LYS A 1 94  ? -23.035 1.999   17.357  1   22.69  ? 86   LYS A C   1 
ATOM   505  O  O   . LYS A 1 94  ? -22.491 3.007   17.816  1   24.187 ? 86   LYS A O   1 
ATOM   506  C  CB  . LYS A 1 94  ? -25.007 2.387   18.988  1   26.459 ? 86   LYS A CB  1 
ATOM   507  C  CG  . LYS A 1 94  ? -26.479 2.118   19.312  1   27.84  ? 86   LYS A CG  1 
ATOM   508  C  CD  . LYS A 1 94  ? -26.906 2.916   20.536  1   32.641 ? 86   LYS A CD  1 
ATOM   509  C  CE  . LYS A 1 94  ? -28.396 3.041   20.615  1   38.442 ? 86   LYS A CE  1 
ATOM   510  N  NZ  . LYS A 1 94  ? -28.675 3.729   21.881  1   36.805 ? 86   LYS A NZ  1 
ATOM   511  N  N   . GLY A 1 95  ? -22.406 1.151   16.516  1   22.214 ? 87   GLY A N   1 
ATOM   512  C  CA  . GLY A 1 95  ? -21.084 1.43    15.958  1   22.064 ? 87   GLY A CA  1 
ATOM   513  C  C   . GLY A 1 95  ? -19.994 1.476   17.044  1   26.549 ? 87   GLY A C   1 
ATOM   514  O  O   . GLY A 1 95  ? -18.907 1.988   16.796  1   23.779 ? 87   GLY A O   1 
ATOM   515  N  N   . GLY A 1 96  ? -20.288 0.919   18.238  1   21.927 ? 88   GLY A N   1 
ATOM   516  C  CA  . GLY A 1 96  ? -19.363 0.998   19.371  1   24.364 ? 88   GLY A CA  1 
ATOM   517  C  C   . GLY A 1 96  ? -19.262 2.375   20.019  1   24.058 ? 88   GLY A C   1 
ATOM   518  O  O   . GLY A 1 96  ? -18.355 2.617   20.823  1   24.71  ? 88   GLY A O   1 
ATOM   519  N  N   . GLU A 1 97  ? -20.224 3.269   19.717  1   25.338 ? 89   GLU A N   1 
ATOM   520  C  CA  . GLU A 1 97  ? -20.177 4.643   20.192  1   29.656 ? 89   GLU A CA  1 
ATOM   521  C  C   . GLU A 1 97  ? -20.265 4.742   21.717  1   25.919 ? 89   GLU A C   1 
ATOM   522  O  O   . GLU A 1 97  ? -19.712 5.691   22.286  1   25.119 ? 89   GLU A O   1 
ATOM   523  C  CB  . GLU A 1 97  ? -21.241 5.523   19.531  1   35.912 ? 89   GLU A CB  1 
ATOM   524  C  CG  . GLU A 1 97  ? -20.835 5.824   18.088  1   49.879 ? 89   GLU A CG  1 
ATOM   525  C  CD  . GLU A 1 97  ? -21.458 6.921   17.24   1   60.78  ? 89   GLU A CD  1 
ATOM   526  O  OE1 . GLU A 1 97  ? -22.21  7.796   17.725  1   70.153 ? 89   GLU A OE1 1 
ATOM   527  O  OE2 . GLU A 1 97  ? -21.151 6.879   16.037  1   69.557 ? 89   GLU A OE2 1 
ATOM   528  N  N   . LEU A 1 98  ? -20.897 3.758   22.368  1   20.739 ? 90   LEU A N   1 
ATOM   529  C  CA  . LEU A 1 98  ? -21.072 3.794   23.818  1   21.528 ? 90   LEU A CA  1 
ATOM   530  C  C   . LEU A 1 98  ? -20.201 2.753   24.546  1   20.088 ? 90   LEU A C   1 
ATOM   531  O  O   . LEU A 1 98  ? -20.49  2.395   25.693  1   20.761 ? 90   LEU A O   1 
ATOM   532  C  CB  . LEU A 1 98  ? -22.562 3.577   24.101  1   22.727 ? 90   LEU A CB  1 
ATOM   533  C  CG  . LEU A 1 98  ? -23.511 4.654   23.557  1   27.609 ? 90   LEU A CG  1 
ATOM   534  C  CD1 . LEU A 1 98  ? -24.948 4.248   23.846  1   29.097 ? 90   LEU A CD1 1 
ATOM   535  C  CD2 . LEU A 1 98  ? -23.195 6.045   24.131  1   29.415 ? 90   LEU A CD2 1 
ATOM   536  N  N   . ASN A 1 99  ? -19.137 2.267   23.895  1   21.989 ? 91   ASN A N   1 
ATOM   537  C  CA  . ASN A 1 99  ? -18.207 1.357   24.578  1   21.519 ? 91   ASN A CA  1 
ATOM   538  C  C   . ASN A 1 99  ? -17.608 2.11    25.753  1   22.6   ? 91   ASN A C   1 
ATOM   539  O  O   . ASN A 1 99  ? -17.384 3.337   25.667  1   22.453 ? 91   ASN A O   1 
ATOM   540  C  CB  . ASN A 1 99  ? -17.161 0.799   23.617  1   22.817 ? 91   ASN A CB  1 
ATOM   541  C  CG  . ASN A 1 99  ? -15.987 1.73    23.409  1   23.859 ? 91   ASN A CG  1 
ATOM   542  O  OD1 . ASN A 1 99  ? -15.089 1.818   24.271  1   25.073 ? 91   ASN A OD1 1 
ATOM   543  N  ND2 . ASN A 1 99  ? -15.959 2.394   22.257  1   24.494 ? 91   ASN A ND2 1 
ATOM   544  N  N   . ALA A 1 100 ? -17.392 1.398   26.873  1   20.321 ? 92   ALA A N   1 
ATOM   545  C  CA  . ALA A 1 100 ? -16.888 2.055   28.069  1   18.645 ? 92   ALA A CA  1 
ATOM   546  C  C   . ALA A 1 100 ? -15.411 1.689   28.25   1   18.622 ? 92   ALA A C   1 
ATOM   547  O  O   . ALA A 1 100 ? -14.969 0.656   27.739  1   19.664 ? 92   ALA A O   1 
ATOM   548  C  CB  . ALA A 1 100 ? -17.69  1.573   29.297  1   20.399 ? 92   ALA A CB  1 
ATOM   549  N  N   . PRO A 1 101 ? -14.578 2.487   28.964  1   20.647 ? 93   PRO A N   1 
ATOM   550  C  CA  . PRO A 1 101 ? -13.169 2.151   29.155  1   19.764 ? 93   PRO A CA  1 
ATOM   551  C  C   . PRO A 1 101 ? -12.921 0.86    29.92   1   20.91  ? 93   PRO A C   1 
ATOM   552  O  O   . PRO A 1 101 ? -11.837 0.276   29.75   1   22.475 ? 93   PRO A O   1 
ATOM   553  C  CB  . PRO A 1 101 ? -12.574 3.325   29.954  1   20.432 ? 93   PRO A CB  1 
ATOM   554  C  CG  . PRO A 1 101 ? -13.806 3.985   30.568  1   22.543 ? 93   PRO A CG  1 
ATOM   555  C  CD  . PRO A 1 101 ? -14.9   3.813   29.543  1   22.34  ? 93   PRO A CD  1 
ATOM   556  N  N   . ILE A 1 102 ? -13.959 0.384   30.636  1   19.227 ? 94   ILE A N   1 
ATOM   557  C  CA  . ILE A 1 102 ? -13.877 -0.857  31.391  1   19.479 ? 94   ILE A CA  1 
ATOM   558  C  C   . ILE A 1 102 ? -14.346 -2.06   30.578  1   19.202 ? 94   ILE A C   1 
ATOM   559  O  O   . ILE A 1 102 ? -14.402 -3.17   31.121  1   19.652 ? 94   ILE A O   1 
ATOM   560  C  CB  . ILE A 1 102 ? -14.616 -0.757  32.758  1   17.731 ? 94   ILE A CB  1 
ATOM   561  C  CG1 . ILE A 1 102 ? -16.139 -0.482  32.559  1   19.218 ? 94   ILE A CG1 1 
ATOM   562  C  CG2 . ILE A 1 102 ? -13.928 0.27    33.666  1   17.516 ? 94   ILE A CG2 1 
ATOM   563  C  CD1 . ILE A 1 102 ? -16.948 -0.591  33.854  1   18.323 ? 94   ILE A CD1 1 
ATOM   564  N  N   . ASP A 1 103 ? -14.65  -1.89   29.265  1   18.22  ? 95   ASP A N   1 
ATOM   565  C  CA  . ASP A 1 103 ? -15.256 -2.98   28.518  1   19.646 ? 95   ASP A CA  1 
ATOM   566  C  C   . ASP A 1 103 ? -14.227 -3.915  27.865  1   17.787 ? 95   ASP A C   1 
ATOM   567  O  O   . ASP A 1 103 ? -14.522 -5.092  27.717  1   20.178 ? 95   ASP A O   1 
ATOM   568  C  CB  . ASP A 1 103 ? -16.073 -2.456  27.35   1   20.868 ? 95   ASP A CB  1 
ATOM   569  C  CG  . ASP A 1 103 ? -17.563 -2.298  27.636  1   25.942 ? 95   ASP A CG  1 
ATOM   570  O  OD1 . ASP A 1 103 ? -18.168 -3.287  28.147  1   22.276 ? 95   ASP A OD1 1 
ATOM   571  O  OD2 . ASP A 1 103 ? -18.114 -1.236  27.271  1   24.326 ? 95   ASP A OD2 1 
ATOM   572  N  N   . GLY A 1 104 ? -13.074 -3.393  27.389  1   18.774 ? 96   GLY A N   1 
ATOM   573  C  CA  . GLY A 1 104 ? -12.255 -4.095  26.381  1   17.102 ? 96   GLY A CA  1 
ATOM   574  C  C   . GLY A 1 104 ? -11.706 -5.445  26.865  1   17.399 ? 96   GLY A C   1 
ATOM   575  O  O   . GLY A 1 104 ? -11.473 -5.648  28.061  1   19.741 ? 96   GLY A O   1 
ATOM   576  N  N   . ASP A 1 105 ? -11.502 -6.372  25.904  1   19.556 ? 97   ASP A N   1 
ATOM   577  C  CA  . ASP A 1 105 ? -10.967 -7.722  26.143  1   18.267 ? 97   ASP A CA  1 
ATOM   578  C  C   . ASP A 1 105 ? -9.718  -7.652  27.027  1   19.29  ? 97   ASP A C   1 
ATOM   579  O  O   . ASP A 1 105 ? -8.814  -6.851  26.755  1   18.306 ? 97   ASP A O   1 
ATOM   580  C  CB  . ASP A 1 105 ? -10.596 -8.363  24.808  1   18.224 ? 97   ASP A CB  1 
ATOM   581  C  CG  . ASP A 1 105 ? -11.809 -8.502  23.887  1   20.264 ? 97   ASP A CG  1 
ATOM   582  O  OD1 . ASP A 1 105 ? -12.711 -9.286  24.235  1   22.636 ? 97   ASP A OD1 1 
ATOM   583  O  OD2 . ASP A 1 105 ? -11.892 -7.762  22.871  1   21.239 ? 97   ASP A OD2 1 
ATOM   584  N  N   . GLY A 1 106 ? -9.719  -8.462  28.104  1   16.66  ? 98   GLY A N   1 
ATOM   585  C  CA  . GLY A 1 106 ? -8.606  -8.531  29.037  1   18.628 ? 98   GLY A CA  1 
ATOM   586  C  C   . GLY A 1 106 ? -7.345  -9.108  28.38   1   18.738 ? 98   GLY A C   1 
ATOM   587  O  O   . GLY A 1 106 ? -7.388  -10.167 27.723  1   18.333 ? 98   GLY A O   1 
ATOM   588  N  N   . THR A 1 107 ? -6.222  -8.424  28.629  1   16.914 ? 99   THR A N   1 
ATOM   589  C  CA  . THR A 1 107 ? -4.93   -8.931  28.193  1   17.605 ? 99   THR A CA  1 
ATOM   590  C  C   . THR A 1 107 ? -3.992  -8.81   29.385  1   19.306 ? 99   THR A C   1 
ATOM   591  O  O   . THR A 1 107 ? -4.029  -7.799  30.082  1   19.322 ? 99   THR A O   1 
ATOM   592  C  CB  . THR A 1 107 ? -4.448  -8.169  26.948  1   20.858 ? 99   THR A CB  1 
ATOM   593  O  OG1 . THR A 1 107 ? -3.148  -8.701  26.677  1   19.288 ? 99   THR A OG1 1 
ATOM   594  C  CG2 . THR A 1 107 ? -4.363  -6.647  27.107  1   19.966 ? 99   THR A CG2 1 
ATOM   595  N  N   . VAL A 1 108 ? -3.209  -9.873  29.62   1   17.604 ? 100  VAL A N   1 
ATOM   596  C  CA  . VAL A 1 108 ? -2.332  -9.874  30.776  1   18.664 ? 100  VAL A CA  1 
ATOM   597  C  C   . VAL A 1 108 ? -0.914  -9.672  30.27   1   18.442 ? 100  VAL A C   1 
ATOM   598  O  O   . VAL A 1 108 ? -0.481  -10.421 29.388  1   18.764 ? 100  VAL A O   1 
ATOM   599  C  CB  . VAL A 1 108 ? -2.469  -11.234 31.498  1   18.699 ? 100  VAL A CB  1 
ATOM   600  C  CG1 . VAL A 1 108 ? -1.419  -11.367 32.629  1   19.4   ? 100  VAL A CG1 1 
ATOM   601  C  CG2 . VAL A 1 108 ? -3.874  -11.389 32.094  1   17.623 ? 100  VAL A CG2 1 
ATOM   602  N  N   . ALA A 1 109 ? -0.2    -8.738  30.902  1   18.317 ? 101  ALA A N   1 
ATOM   603  C  CA  . ALA A 1 109 ? 1.235   -8.582  30.7    1   18.674 ? 101  ALA A CA  1 
ATOM   604  C  C   . ALA A 1 109 ? 1.932   -9.127  31.951  1   20.021 ? 101  ALA A C   1 
ATOM   605  O  O   . ALA A 1 109 ? 1.554   -8.797  33.074  1   22.872 ? 101  ALA A O   1 
ATOM   606  C  CB  . ALA A 1 109 ? 1.552   -7.113  30.471  1   19.263 ? 101  ALA A CB  1 
ATOM   607  N  N   . ALA A 1 110 ? 2.938   -9.98   31.748  1   20.349 ? 102  ALA A N   1 
ATOM   608  C  CA  . ALA A 1 110 ? 3.723   -10.517 32.847  1   18.577 ? 102  ALA A CA  1 
ATOM   609  C  C   . ALA A 1 110 ? 5.164   -10.053 32.699  1   19.433 ? 102  ALA A C   1 
ATOM   610  O  O   . ALA A 1 110 ? 5.735   -10.099 31.6    1   20.434 ? 102  ALA A O   1 
ATOM   611  C  CB  . ALA A 1 110 ? 3.682   -12.04  32.763  1   18.025 ? 102  ALA A CB  1 
ATOM   612  N  N   . PHE A 1 111 ? 5.708   -9.573  33.832  1   19.198 ? 103  PHE A N   1 
ATOM   613  C  CA  . PHE A 1 111 ? 7.097   -9.152  33.908  1   19.877 ? 103  PHE A CA  1 
ATOM   614  C  C   . PHE A 1 111 ? 7.771   -10.004 34.974  1   18.245 ? 103  PHE A C   1 
ATOM   615  O  O   . PHE A 1 111 ? 7.494   -9.805  36.163  1   19.464 ? 103  PHE A O   1 
ATOM   616  C  CB  . PHE A 1 111 ? 7.23    -7.665  34.275  1   19.549 ? 103  PHE A CB  1 
ATOM   617  C  CG  . PHE A 1 111 ? 6.582   -6.728  33.256  1   20.648 ? 103  PHE A CG  1 
ATOM   618  C  CD1 . PHE A 1 111 ? 5.24    -6.361  33.39   1   22.18  ? 103  PHE A CD1 1 
ATOM   619  C  CD2 . PHE A 1 111 ? 7.324   -6.204  32.2    1   20.943 ? 103  PHE A CD2 1 
ATOM   620  C  CE1 . PHE A 1 111 ? 4.633   -5.498  32.457  1   24.028 ? 103  PHE A CE1 1 
ATOM   621  C  CE2 . PHE A 1 111 ? 6.745   -5.301  31.285  1   24.248 ? 103  PHE A CE2 1 
ATOM   622  C  CZ  . PHE A 1 111 ? 5.4     -4.967  31.415  1   23.507 ? 103  PHE A CZ  1 
ATOM   623  N  N   . ARG A 1 112 ? 8.607   -10.95  34.533  1   20.125 ? 104  ARG A N   1 
ATOM   624  C  CA  . ARG A 1 112 ? 9.124   -11.969 35.451  1   17.9   ? 104  ARG A CA  1 
ATOM   625  C  C   . ARG A 1 112 ? 10.569  -11.599 35.793  1   19.698 ? 104  ARG A C   1 
ATOM   626  O  O   . ARG A 1 112 ? 11.346  -11.383 34.883  1   18.902 ? 104  ARG A O   1 
ATOM   627  C  CB  . ARG A 1 112 ? 8.926   -13.401 34.945  1   18.99  ? 104  ARG A CB  1 
ATOM   628  C  CG  . ARG A 1 112 ? 9.556   -14.386 35.932  1   20.268 ? 104  ARG A CG  1 
ATOM   629  C  CD  . ARG A 1 112 ? 9.116   -15.809 35.653  1   18.925 ? 104  ARG A CD  1 
ATOM   630  N  NE  . ARG A 1 112 ? 7.666   -15.941 35.874  1   21.378 ? 104  ARG A NE  1 
ATOM   631  C  CZ  . ARG A 1 112 ? 6.97    -17.023 35.614  1   20.957 ? 104  ARG A CZ  1 
ATOM   632  N  NH1 . ARG A 1 112 ? 7.566   -18.071 35.046  1   20.244 ? 104  ARG A NH1 1 
ATOM   633  N  NH2 . ARG A 1 112 ? 5.669   -17.044 35.864  1   22.884 ? 104  ARG A NH2 1 
ATOM   634  N  N   . PHE A 1 113 ? 10.84   -11.46  37.1    1   20.746 ? 105  PHE A N   1 
ATOM   635  C  CA  . PHE A 1 113 ? 12.117  -11.047 37.674  1   21.554 ? 105  PHE A CA  1 
ATOM   636  C  C   . PHE A 1 113 ? 12.738  -12.273 38.348  1   20.275 ? 105  PHE A C   1 
ATOM   637  O  O   . PHE A 1 113 ? 12.17   -12.847 39.284  1   21.588 ? 105  PHE A O   1 
ATOM   638  C  CB  . PHE A 1 113 ? 11.853  -9.98   38.745  1   21.556 ? 105  PHE A CB  1 
ATOM   639  C  CG  . PHE A 1 113 ? 11.327  -8.65   38.227  1   22.699 ? 105  PHE A CG  1 
ATOM   640  C  CD1 . PHE A 1 113 ? 9.976   -8.515  37.863  1   23.136 ? 105  PHE A CD1 1 
ATOM   641  C  CD2 . PHE A 1 113 ? 12.179  -7.545  38.074  1   22.538 ? 105  PHE A CD2 1 
ATOM   642  C  CE1 . PHE A 1 113 ? 9.505   -7.306  37.361  1   22.215 ? 105  PHE A CE1 1 
ATOM   643  C  CE2 . PHE A 1 113 ? 11.697  -6.317  37.596  1   24.124 ? 105  PHE A CE2 1 
ATOM   644  C  CZ  . PHE A 1 113 ? 10.366  -6.219  37.206  1   23.961 ? 105  PHE A CZ  1 
ATOM   645  N  N   . LYS A 1 114 ? 13.956  -12.599 37.896  1   23.913 ? 106  LYS A N   1 
ATOM   646  C  CA  . LYS A 1 114 ? 14.681  -13.744 38.432  1   24.094 ? 106  LYS A CA  1 
ATOM   647  C  C   . LYS A 1 114 ? 16.157  -13.475 38.199  1   25.295 ? 106  LYS A C   1 
ATOM   648  O  O   . LYS A 1 114 ? 16.588  -13.307 37.054  1   24.301 ? 106  LYS A O   1 
ATOM   649  C  CB  . LYS A 1 114 ? 14.143  -15.057 37.859  1   27.423 ? 106  LYS A CB  1 
ATOM   650  C  CG  . LYS A 1 114 ? 14.758  -16.296 38.504  1   33.442 ? 106  LYS A CG  1 
ATOM   651  C  CD  . LYS A 1 114 ? 14.108  -17.577 38.011  1   29.327 ? 106  LYS A CD  1 
ATOM   652  C  CE  . LYS A 1 114 ? 15.067  -18.657 38.444  1   41.608 ? 106  LYS A CE  1 
ATOM   653  N  NZ  . LYS A 1 114 ? 14.28   -19.876 38.321  1   55.905 ? 106  LYS A NZ  1 
ATOM   654  N  N   . ASP A 1 115 ? 16.884  -13.337 39.31   1   30.311 ? 107  ASP A N   1 
ATOM   655  C  CA  . ASP A 1 115 ? 18.337  -13.133 39.3    1   31.862 ? 107  ASP A CA  1 
ATOM   656  C  C   . ASP A 1 115 ? 18.697  -11.88  38.508  1   28.296 ? 107  ASP A C   1 
ATOM   657  O  O   . ASP A 1 115 ? 19.709  -11.834 37.82   1   33.82  ? 107  ASP A O   1 
ATOM   658  C  CB  . ASP A 1 115 ? 19.073  -14.373 38.799  1   35.605 ? 107  ASP A CB  1 
ATOM   659  C  CG  . ASP A 1 115 ? 18.748  -15.681 39.507  1   49.415 ? 107  ASP A CG  1 
ATOM   660  O  OD1 . ASP A 1 115 ? 18.68   -15.688 40.763  1   51.012 ? 107  ASP A OD1 1 
ATOM   661  O  OD2 . ASP A 1 115 ? 18.58   -16.695 38.798  1   59.922 ? 107  ASP A OD2 1 
ATOM   662  N  N   . GLY A 1 116 ? 17.872  -10.838 38.636  1   23.957 ? 108  GLY A N   1 
ATOM   663  C  CA  . GLY A 1 116 ? 18.155  -9.561  38.015  1   26.198 ? 108  GLY A CA  1 
ATOM   664  C  C   . GLY A 1 116 ? 17.758  -9.536  36.534  1   26.414 ? 108  GLY A C   1 
ATOM   665  O  O   . GLY A 1 116 ? 17.926  -8.497  35.931  1   32.109 ? 108  GLY A O   1 
ATOM   666  N  N   . LYS A 1 117 ? 17.286  -10.644 35.956  1   25.658 ? 109  LYS A N   1 
ATOM   667  C  CA  . LYS A 1 117 ? 16.83   -10.606 34.561  1   22.287 ? 109  LYS A CA  1 
ATOM   668  C  C   . LYS A 1 117 ? 15.305  -10.406 34.565  1   20.306 ? 109  LYS A C   1 
ATOM   669  O  O   . LYS A 1 117 ? 14.618  -10.972 35.411  1   23.746 ? 109  LYS A O   1 
ATOM   670  C  CB  . LYS A 1 117 ? 17.158  -11.921 33.838  1   26.654 ? 109  LYS A CB  1 
ATOM   671  C  CG  . LYS A 1 117 ? 16.665  -12.027 32.353  1   29.355 ? 109  LYS A CG  1 
ATOM   672  C  CD  . LYS A 1 117 ? 17.037  -13.064 31.273  1   29.915 ? 109  LYS A CD  1 
ATOM   673  C  CE  . LYS A 1 117 ? 16.676  -14.503 31.519  1   31.966 ? 109  LYS A CE  1 
ATOM   674  N  NZ  . LYS A 1 117 ? 15.244  -14.69  31.746  1   34.924 ? 109  LYS A NZ  1 
ATOM   675  N  N   . VAL A 1 118 ? 14.782  -9.708  33.548  1   20.725 ? 110  VAL A N   1 
ATOM   676  C  CA  . VAL A 1 118 ? 13.342  -9.522  33.404  1   20.1   ? 110  VAL A CA  1 
ATOM   677  C  C   . VAL A 1 118 ? 12.933  -10.051 32.03   1   18.076 ? 110  VAL A C   1 
ATOM   678  O  O   . VAL A 1 118 ? 13.527  -9.65   31.036  1   21.663 ? 110  VAL A O   1 
ATOM   679  C  CB  . VAL A 1 118 ? 12.949  -8.028  33.486  1   20.976 ? 110  VAL A CB  1 
ATOM   680  C  CG1 . VAL A 1 118 ? 11.426  -7.918  33.514  1   24.18  ? 110  VAL A CG1 1 
ATOM   681  C  CG2 . VAL A 1 118 ? 13.527  -7.366  34.728  1   24.679 ? 110  VAL A CG2 1 
ATOM   682  N  N   . ASP A 1 119 ? 11.895  -10.901 32.015  1   19.895 ? 111  ASP A N   1 
ATOM   683  C  CA  . ASP A 1 119 ? 11.256  -11.289 30.771  1   19.465 ? 111  ASP A CA  1 
ATOM   684  C  C   . ASP A 1 119 ? 9.826   -10.731 30.802  1   19.756 ? 111  ASP A C   1 
ATOM   685  O  O   . ASP A 1 119 ? 9.239   -10.485 31.86   1   19.619 ? 111  ASP A O   1 
ATOM   686  C  CB  . ASP A 1 119 ? 11.222  -12.8   30.603  1   20.226 ? 111  ASP A CB  1 
ATOM   687  C  CG  . ASP A 1 119 ? 12.575  -13.505 30.527  1   21.955 ? 111  ASP A CG  1 
ATOM   688  O  OD1 . ASP A 1 119 ? 13.557  -12.876 30.092  1   21.536 ? 111  ASP A OD1 1 
ATOM   689  O  OD2 . ASP A 1 119 ? 12.586  -14.728 30.794  1   25.488 ? 111  ASP A OD2 1 
ATOM   690  N  N   . TYR A 1 120 ? 9.293   -10.598 29.597  1   18.958 ? 112  TYR A N   1 
ATOM   691  C  CA  . TYR A 1 120 ? 7.933   -10.09  29.403  1   19.297 ? 112  TYR A CA  1 
ATOM   692  C  C   . TYR A 1 120 ? 7.158   -11.053 28.513  1   19.735 ? 112  TYR A C   1 
ATOM   693  O  O   . TYR A 1 120 ? 7.675   -11.552 27.517  1   19.895 ? 112  TYR A O   1 
ATOM   694  C  CB  . TYR A 1 120 ? 8.026   -8.702  28.759  1   17.975 ? 112  TYR A CB  1 
ATOM   695  C  CG  . TYR A 1 120 ? 6.796   -8.193  28.021  1   22.443 ? 112  TYR A CG  1 
ATOM   696  C  CD1 . TYR A 1 120 ? 5.729   -7.576  28.688  1   24.928 ? 112  TYR A CD1 1 
ATOM   697  C  CD2 . TYR A 1 120 ? 6.746   -8.327  26.633  1   23.91  ? 112  TYR A CD2 1 
ATOM   698  C  CE1 . TYR A 1 120 ? 4.619   -7.14   27.96   1   24.282 ? 112  TYR A CE1 1 
ATOM   699  C  CE2 . TYR A 1 120 ? 5.661   -7.878  25.905  1   27.846 ? 112  TYR A CE2 1 
ATOM   700  C  CZ  . TYR A 1 120 ? 4.601   -7.291  26.577  1   28.889 ? 112  TYR A CZ  1 
ATOM   701  O  OH  . TYR A 1 120 ? 3.623   -6.884  25.71   1   30.825 ? 112  TYR A OH  1 
ATOM   702  N  N   . ARG A 1 121 ? 5.876   -11.216 28.838  1   18.748 ? 113  ARG A N   1 
ATOM   703  C  CA  . ARG A 1 121 ? 4.948   -11.915 27.965  1   21.354 ? 113  ARG A CA  1 
ATOM   704  C  C   . ARG A 1 121 ? 3.603   -11.229 28.12   1   20.96  ? 113  ARG A C   1 
ATOM   705  O  O   . ARG A 1 121 ? 3.197   -10.897 29.246  1   20.951 ? 113  ARG A O   1 
ATOM   706  C  CB  . ARG A 1 121 ? 4.727   -13.398 28.355  1   22.971 ? 113  ARG A CB  1 
ATOM   707  C  CG  . ARG A 1 121 ? 3.687   -14.095 27.476  1   19.952 ? 113  ARG A CG  1 
ATOM   708  C  CD  . ARG A 1 121 ? 3.537   -15.582 27.896  1   20.546 ? 113  ARG A CD  1 
ATOM   709  N  NE  . ARG A 1 121 ? 4.665   -16.404 27.417  1   24.381 ? 113  ARG A NE  1 
ATOM   710  C  CZ  . ARG A 1 121 ? 4.762   -16.967 26.214  1   26.331 ? 113  ARG A CZ  1 
ATOM   711  N  NH1 . ARG A 1 121 ? 3.889   -16.68  25.273  1   21.455 ? 113  ARG A NH1 1 
ATOM   712  N  NH2 . ARG A 1 121 ? 5.758   -17.801 25.942  1   23.67  ? 113  ARG A NH2 1 
ATOM   713  N  N   . GLN A 1 122 ? 2.917   -11.089 26.984  1   18.502 ? 114  GLN A N   1 
ATOM   714  C  CA  . GLN A 1 122 ? 1.576   -10.542 27.019  1   19.422 ? 114  GLN A CA  1 
ATOM   715  C  C   . GLN A 1 122 ? 0.656   -11.435 26.197  1   18.019 ? 114  GLN A C   1 
ATOM   716  O  O   . GLN A 1 122 ? 1.061   -11.946 25.134  1   18.422 ? 114  GLN A O   1 
ATOM   717  C  CB  . GLN A 1 122 ? 1.553   -9.142  26.449  1   20.207 ? 114  GLN A CB  1 
ATOM   718  C  CG  . GLN A 1 122 ? 0.14    -8.554  26.554  1   21.725 ? 114  GLN A CG  1 
ATOM   719  C  CD  . GLN A 1 122 ? 0.127   -7.057  26.548  1   26.527 ? 114  GLN A CD  1 
ATOM   720  O  OE1 . GLN A 1 122 ? 1.14    -6.425  26.286  1   30.137 ? 114  GLN A OE1 1 
ATOM   721  N  NE2 . GLN A 1 122 ? -1.045  -6.475  26.81   1   27.505 ? 114  GLN A NE2 1 
ATOM   722  N  N   . ARG A 1 123 ? -0.557  -11.647 26.72   1   18.71  ? 115  ARG A N   1 
ATOM   723  C  CA  . ARG A 1 123 ? -1.502  -12.474 25.978  1   17.511 ? 115  ARG A CA  1 
ATOM   724  C  C   . ARG A 1 123 ? -2.924  -12.109 26.392  1   16.243 ? 115  ARG A C   1 
ATOM   725  O  O   . ARG A 1 123 ? -3.244  -11.916 27.578  1   17.97  ? 115  ARG A O   1 
ATOM   726  C  CB  . ARG A 1 123 ? -1.187  -13.943 26.329  1   19.264 ? 115  ARG A CB  1 
ATOM   727  C  CG  . ARG A 1 123 ? -1.75   -14.897 25.291  1   20.52  ? 115  ARG A CG  1 
ATOM   728  C  CD  . ARG A 1 123 ? -1.167  -16.298 25.599  1   21.217 ? 115  ARG A CD  1 
ATOM   729  N  NE  . ARG A 1 123 ? -1.643  -17.25  24.589  1   24.667 ? 115  ARG A NE  1 
ATOM   730  C  CZ  . ARG A 1 123 ? -1.101  -18.465 24.423  1   30.367 ? 115  ARG A CZ  1 
ATOM   731  N  NH1 . ARG A 1 123 ? -0.116  -18.905 25.185  1   29.139 ? 115  ARG A NH1 1 
ATOM   732  N  NH2 . ARG A 1 123 ? -1.602  -19.29  23.53   1   30.174 ? 115  ARG A NH2 1 
ATOM   733  N  N   . PHE A 1 124 ? -3.825  -12.242 25.405  1   18.388 ? 116  PHE A N   1 
ATOM   734  C  CA  . PHE A 1 124 ? -5.229  -12.067 25.726  1   16.483 ? 116  PHE A CA  1 
ATOM   735  C  C   . PHE A 1 124 ? -5.76   -13.257 26.497  1   17.493 ? 116  PHE A C   1 
ATOM   736  O  O   . PHE A 1 124 ? -5.385  -14.409 26.226  1   19.659 ? 116  PHE A O   1 
ATOM   737  C  CB  . PHE A 1 124 ? -6.061  -12.041 24.442  1   16.388 ? 116  PHE A CB  1 
ATOM   738  C  CG  . PHE A 1 124 ? -6.044  -10.631 23.849  1   18.646 ? 116  PHE A CG  1 
ATOM   739  C  CD1 . PHE A 1 124 ? -6.744  -9.586  24.471  1   19.453 ? 116  PHE A CD1 1 
ATOM   740  C  CD2 . PHE A 1 124 ? -5.42   -10.381 22.618  1   16.758 ? 116  PHE A CD2 1 
ATOM   741  C  CE1 . PHE A 1 124 ? -6.733  -8.29   23.918  1   19.253 ? 116  PHE A CE1 1 
ATOM   742  C  CE2 . PHE A 1 124 ? -5.417  -9.091  22.054  1   20.121 ? 116  PHE A CE2 1 
ATOM   743  C  CZ  . PHE A 1 124 ? -6.072  -8.05   22.688  1   18.558 ? 116  PHE A CZ  1 
ATOM   744  N  N   . VAL A 1 125 ? -6.663  -12.956 27.445  1   18.586 ? 117  VAL A N   1 
ATOM   745  C  CA  . VAL A 1 125 ? -7.479  -14.02  28.038  1   17.762 ? 117  VAL A CA  1 
ATOM   746  C  C   . VAL A 1 125 ? -8.408  -14.571 26.968  1   19.18  ? 117  VAL A C   1 
ATOM   747  O  O   . VAL A 1 125 ? -9.177  -13.804 26.372  1   19.594 ? 117  VAL A O   1 
ATOM   748  C  CB  . VAL A 1 125 ? -8.297  -13.532 29.255  1   19.743 ? 117  VAL A CB  1 
ATOM   749  C  CG1 . VAL A 1 125 ? -8.923  -14.733 29.974  1   19.021 ? 117  VAL A CG1 1 
ATOM   750  C  CG2 . VAL A 1 125 ? -7.433  -12.779 30.245  1   17.942 ? 117  VAL A CG2 1 
ATOM   751  N  N   . GLU A 1 126 ? -8.427  -15.91  26.817  1   19.059 ? 118  GLU A N   1 
ATOM   752  C  CA  . GLU A 1 126 ? -9.316  -16.496 25.825  1   20.183 ? 118  GLU A CA  1 
ATOM   753  C  C   . GLU A 1 126 ? -10.693 -16.699 26.446  1   21.566 ? 118  GLU A C   1 
ATOM   754  O  O   . GLU A 1 126 ? -11.168 -17.831 26.576  1   20.924 ? 118  GLU A O   1 
ATOM   755  C  CB  . GLU A 1 126 ? -8.795  -17.856 25.344  1   25.251 ? 118  GLU A CB  1 
ATOM   756  C  CG  . GLU A 1 126 ? -7.686  -17.801 24.325  1   30.829 ? 118  GLU A CG  1 
ATOM   757  C  CD  . GLU A 1 126 ? -7.463  -19.248 23.846  1   37.199 ? 118  GLU A CD  1 
ATOM   758  O  OE1 . GLU A 1 126 ? -8.101  -20.272 24.27   1   32.758 ? 118  GLU A OE1 1 
ATOM   759  O  OE2 . GLU A 1 126 ? -6.571  -19.343 22.993  1   32.444 ? 118  GLU A OE2 1 
ATOM   760  N  N   . THR A 1 127 ? -11.375 -15.589 26.805  1   19.352 ? 119  THR A N   1 
ATOM   761  C  CA  . THR A 1 127 ? -12.742 -15.668 27.319  1   18.535 ? 119  THR A CA  1 
ATOM   762  C  C   . THR A 1 127 ? -13.632 -16.225 26.208  1   18.319 ? 119  THR A C   1 
ATOM   763  O  O   . THR A 1 127 ? -13.271 -16.139 25.017  1   18.389 ? 119  THR A O   1 
ATOM   764  C  CB  . THR A 1 127 ? -13.243 -14.296 27.775  1   18.056 ? 119  THR A CB  1 
ATOM   765  O  OG1 . THR A 1 127 ? -13.408 -13.506 26.592  1   17.836 ? 119  THR A OG1 1 
ATOM   766  C  CG2 . THR A 1 127 ? -12.301 -13.609 28.757  1   17.947 ? 119  THR A CG2 1 
ATOM   767  N  N   . ASP A 1 128 ? -14.795 -16.765 26.593  1   18.783 ? 120  ASP A N   1 
ATOM   768  C  CA  . ASP A 1 128 ? -15.755 -17.182 25.573  1   20.605 ? 120  ASP A CA  1 
ATOM   769  C  C   . ASP A 1 128 ? -16.07  -16.045 24.605  1   20.598 ? 120  ASP A C   1 
ATOM   770  O  O   . ASP A 1 128 ? -16.167 -16.275 23.388  1   19.569 ? 120  ASP A O   1 
ATOM   771  C  CB  . ASP A 1 128 ? -16.997 -17.795 26.199  1   19.867 ? 120  ASP A CB  1 
ATOM   772  C  CG  . ASP A 1 128 ? -16.761 -19.189 26.737  1   21.13  ? 120  ASP A CG  1 
ATOM   773  O  OD1 . ASP A 1 128 ? -15.692 -19.767 26.396  1   22.042 ? 120  ASP A OD1 1 
ATOM   774  O  OD2 . ASP A 1 128 ? -17.638 -19.673 27.497  1   22.669 ? 120  ASP A OD2 1 
ATOM   775  N  N   . ARG A 1 129 ? -16.175 -14.828 25.155  1   20.39  ? 121  ARG A N   1 
ATOM   776  C  CA  . ARG A 1 129 ? -16.425 -13.638 24.333  1   19.796 ? 121  ARG A CA  1 
ATOM   777  C  C   . ARG A 1 129 ? -15.315 -13.37  23.33   1   18.163 ? 121  ARG A C   1 
ATOM   778  O  O   . ARG A 1 129 ? -15.582 -13.153 22.133  1   19.47  ? 121  ARG A O   1 
ATOM   779  C  CB  . ARG A 1 129 ? -16.603 -12.465 25.286  1   19.492 ? 121  ARG A CB  1 
ATOM   780  C  CG  . ARG A 1 129 ? -16.507 -11.077 24.661  1   19.139 ? 121  ARG A CG  1 
ATOM   781  C  CD  . ARG A 1 129 ? -17.242 -10.142 25.566  1   19.848 ? 121  ARG A CD  1 
ATOM   782  N  NE  . ARG A 1 129 ? -17.161 -8.766  25.058  1   17.942 ? 121  ARG A NE  1 
ATOM   783  C  CZ  . ARG A 1 129 ? -17.839 -7.762  25.686  1   19.009 ? 121  ARG A CZ  1 
ATOM   784  N  NH1 . ARG A 1 129 ? -18.638 -8.028  26.745  1   16.803 ? 121  ARG A NH1 1 
ATOM   785  N  NH2 . ARG A 1 129 ? -17.678 -6.529  25.239  1   20.567 ? 121  ARG A NH2 1 
ATOM   786  N  N   . PHE A 1 130 ? -14.065 -13.407 23.829  1   19.04  ? 122  PHE A N   1 
ATOM   787  C  CA  . PHE A 1 130 ? -12.928 -13.169 22.971  1   17.664 ? 122  PHE A CA  1 
ATOM   788  C  C   . PHE A 1 130 ? -12.906 -14.196 21.848  1   18.428 ? 122  PHE A C   1 
ATOM   789  O  O   . PHE A 1 130 ? -12.593 -13.845 20.705  1   19.865 ? 122  PHE A O   1 
ATOM   790  C  CB  . PHE A 1 130 ? -11.68  -13.284 23.843  1   20.769 ? 122  PHE A CB  1 
ATOM   791  C  CG  . PHE A 1 130 ? -10.394 -13.312 23.04   1   18.369 ? 122  PHE A CG  1 
ATOM   792  C  CD1 . PHE A 1 130 ? -9.764  -12.106 22.657  1   17.838 ? 122  PHE A CD1 1 
ATOM   793  C  CD2 . PHE A 1 130 ? -9.8    -14.534 22.694  1   18.121 ? 122  PHE A CD2 1 
ATOM   794  C  CE1 . PHE A 1 130 ? -8.566  -12.145 21.936  1   18.928 ? 122  PHE A CE1 1 
ATOM   795  C  CE2 . PHE A 1 130 ? -8.555  -14.566 22.014  1   17.823 ? 122  PHE A CE2 1 
ATOM   796  C  CZ  . PHE A 1 130 ? -7.954  -13.372 21.633  1   18.445 ? 122  PHE A CZ  1 
ATOM   797  N  N   . LYS A 1 131 ? -13.133 -15.479 22.21   1   19.561 ? 123  LYS A N   1 
ATOM   798  C  CA  . LYS A 1 131 ? -13.031 -16.539 21.211  1   18.67  ? 123  LYS A CA  1 
ATOM   799  C  C   . LYS A 1 131 ? -14.09  -16.364 20.125  1   20.449 ? 123  LYS A C   1 
ATOM   800  O  O   . LYS A 1 131 ? -13.806 -16.542 18.942  1   20.697 ? 123  LYS A O   1 
ATOM   801  C  CB  . LYS A 1 131 ? -13.193 -17.94  21.824  1   18.833 ? 123  LYS A CB  1 
ATOM   802  C  CG  . LYS A 1 131 ? -12.041 -18.271 22.841  1   17.621 ? 123  LYS A CG  1 
ATOM   803  C  CD  . LYS A 1 131 ? -11.952 -19.767 23.172  1   20.26  ? 123  LYS A CD  1 
ATOM   804  C  CE  . LYS A 1 131 ? -13.121 -20.424 23.879  1   20.961 ? 123  LYS A CE  1 
ATOM   805  N  NZ  . LYS A 1 131 ? -14.161 -20.715 22.866  1   22.52  ? 123  LYS A NZ  1 
ATOM   806  N  N   . VAL A 1 132 ? -15.318 -16.026 20.529  1   20.439 ? 124  VAL A N   1 
ATOM   807  C  CA  . VAL A 1 132 ? -16.373 -15.795 19.55   1   21.555 ? 124  VAL A CA  1 
ATOM   808  C  C   . VAL A 1 132 ? -15.931 -14.694 18.589  1   19.765 ? 124  VAL A C   1 
ATOM   809  O  O   . VAL A 1 132 ? -16.046 -14.837 17.363  1   22.438 ? 124  VAL A O   1 
ATOM   810  C  CB  . VAL A 1 132 ? -17.687 -15.441 20.287  1   24.599 ? 124  VAL A CB  1 
ATOM   811  C  CG1 . VAL A 1 132 ? -18.678 -14.72  19.382  1   31.489 ? 124  VAL A CG1 1 
ATOM   812  C  CG2 . VAL A 1 132 ? -18.315 -16.69  20.875  1   25.785 ? 124  VAL A CG2 1 
ATOM   813  N  N   . GLU A 1 133 ? -15.437 -13.577 19.151  1   18.234 ? 125  GLU A N   1 
ATOM   814  C  CA  . GLU A 1 133 ? -15.144 -12.425 18.31   1   18.92  ? 125  GLU A CA  1 
ATOM   815  C  C   . GLU A 1 133 ? -13.942 -12.657 17.401  1   19.312 ? 125  GLU A C   1 
ATOM   816  O  O   . GLU A 1 133 ? -13.901 -12.151 16.262  1   20.286 ? 125  GLU A O   1 
ATOM   817  C  CB  . GLU A 1 133 ? -15.034 -11.135 19.12   1   22.004 ? 125  GLU A CB  1 
ATOM   818  C  CG  . GLU A 1 133 ? -16.376 -10.702 19.716  1   21.01  ? 125  GLU A CG  1 
ATOM   819  C  CD  . GLU A 1 133 ? -16.386 -9.355  20.394  1   21.456 ? 125  GLU A CD  1 
ATOM   820  O  OE1 . GLU A 1 133 ? -15.286 -8.787  20.683  1   22.792 ? 125  GLU A OE1 1 
ATOM   821  O  OE2 . GLU A 1 133 ? -17.44  -8.716  20.528  1   19.771 ? 125  GLU A OE2 1 
ATOM   822  N  N   . ARG A 1 134 ? -12.933 -13.384 17.905  1   19.395 ? 126  ARG A N   1 
ATOM   823  C  CA  . ARG A 1 134 ? -11.737 -13.614 17.117  1   18.639 ? 126  ARG A CA  1 
ATOM   824  C  C   . ARG A 1 134 ? -12.091 -14.558 15.964  1   21.256 ? 126  ARG A C   1 
ATOM   825  O  O   . ARG A 1 134 ? -11.723 -14.265 14.819  1   21.306 ? 126  ARG A O   1 
ATOM   826  C  CB  . ARG A 1 134 ? -10.586 -14.12  18.005  1   19.557 ? 126  ARG A CB  1 
ATOM   827  C  CG  . ARG A 1 134 ? -9.378  -14.409 17.116  1   19.328 ? 126  ARG A CG  1 
ATOM   828  C  CD  . ARG A 1 134 ? -8.067  -14.491 17.898  1   19.498 ? 126  ARG A CD  1 
ATOM   829  N  NE  . ARG A 1 134 ? -7.633  -13.129 18.211  1   18.76  ? 126  ARG A NE  1 
ATOM   830  C  CZ  . ARG A 1 134 ? -6.457  -12.828 18.746  1   22.742 ? 126  ARG A CZ  1 
ATOM   831  N  NH1 . ARG A 1 134 ? -5.567  -13.79  19.008  1   20.854 ? 126  ARG A NH1 1 
ATOM   832  N  NH2 . ARG A 1 134 ? -6.214  -11.545 19.02   1   20.817 ? 126  ARG A NH2 1 
ATOM   833  N  N   . ARG A 1 135 ? -12.85  -15.625 16.286  1   21.202 ? 127  ARG A N   1 
ATOM   834  C  CA  . ARG A 1 135 ? -13.227 -16.608 15.263  1   23.271 ? 127  ARG A CA  1 
ATOM   835  C  C   . ARG A 1 135 ? -14.106 -15.969 14.189  1   24.974 ? 127  ARG A C   1 
ATOM   836  O  O   . ARG A 1 135 ? -13.959 -16.313 13.005  1   25.57  ? 127  ARG A O   1 
ATOM   837  C  CB  . ARG A 1 135 ? -13.904 -17.817 15.892  1   22.793 ? 127  ARG A CB  1 
ATOM   838  C  CG  . ARG A 1 135 ? -12.911 -18.659 16.68   1   22.498 ? 127  ARG A CG  1 
ATOM   839  C  CD  . ARG A 1 135 ? -13.589 -19.768 17.478  1   24.5   ? 127  ARG A CD  1 
ATOM   840  N  NE  . ARG A 1 135 ? -14.132 -20.732 16.533  1   26.754 ? 127  ARG A NE  1 
ATOM   841  C  CZ  . ARG A 1 135 ? -13.477 -21.602 15.78   1   31.986 ? 127  ARG A CZ  1 
ATOM   842  N  NH1 . ARG A 1 135 ? -12.205 -21.91  15.992  1   28.899 ? 127  ARG A NH1 1 
ATOM   843  N  NH2 . ARG A 1 135 ? -14.175 -22.237 14.856  1   37.433 ? 127  ARG A NH2 1 
ATOM   844  N  N   . ALA A 1 136 ? -14.971 -15.007 14.589  1   23.373 ? 128  ALA A N   1 
ATOM   845  C  CA  . ALA A 1 136 ? -15.835 -14.319 13.628  1   25.909 ? 128  ALA A CA  1 
ATOM   846  C  C   . ALA A 1 136 ? -15.143 -13.139 12.94   1   25.381 ? 128  ALA A C   1 
ATOM   847  O  O   . ALA A 1 136 ? -15.723 -12.549 12      1   24.657 ? 128  ALA A O   1 
ATOM   848  C  CB  . ALA A 1 136 ? -17.118 -13.851 14.302  1   22.47  ? 128  ALA A CB  1 
ATOM   849  N  N   . ARG A 1 137 ? -13.979 -12.724 13.468  1   24.124 ? 129  ARG A N   1 
ATOM   850  C  CA  . ARG A 1 137 ? -13.313 -11.463 13.131  1   22.75  ? 129  ARG A CA  1 
ATOM   851  C  C   . ARG A 1 137 ? -14.311 -10.296 13.21   1   25.203 ? 129  ARG A C   1 
ATOM   852  O  O   . ARG A 1 137 ? -14.417 -9.474  12.302  1   23.626 ? 129  ARG A O   1 
ATOM   853  C  CB  . ARG A 1 137 ? -12.649 -11.633 11.753  1   26.417 ? 129  ARG A CB  1 
ATOM   854  C  CG  . ARG A 1 137 ? -11.593 -10.556 11.564  1   29.036 ? 129  ARG A CG  1 
ATOM   855  C  CD  . ARG A 1 137 ? -10.701 -10.867 10.331  1   40.271 ? 129  ARG A CD  1 
ATOM   856  N  NE  . ARG A 1 137 ? -9.725  -11.967 10.175  1   49.166 ? 129  ARG A NE  1 
ATOM   857  C  CZ  . ARG A 1 137 ? -8.384  -11.874 10.135  1   37.361 ? 129  ARG A CZ  1 
ATOM   858  N  NH1 . ARG A 1 137 ? -7.816  -10.74  10.496  1   35.038 ? 129  ARG A NH1 1 
ATOM   859  N  NH2 . ARG A 1 137 ? -7.609  -12.912 9.843   1   37.372 ? 129  ARG A NH2 1 
ATOM   860  N  N   . LYS A 1 138 ? -15.085 -10.204 14.298  1   22.816 ? 130  LYS A N   1 
ATOM   861  C  CA  . LYS A 1 138 ? -16.219 -9.282  14.298  1   23.916 ? 130  LYS A CA  1 
ATOM   862  C  C   . LYS A 1 138 ? -16.68  -9.097  15.74   1   23.09  ? 130  LYS A C   1 
ATOM   863  O  O   . LYS A 1 138 ? -16.793 -10.072 16.461  1   21.513 ? 130  LYS A O   1 
ATOM   864  C  CB  . LYS A 1 138 ? -17.379 -9.885  13.487  1   28.813 ? 130  LYS A CB  1 
ATOM   865  C  CG  . LYS A 1 138 ? -18.624 -9.044  13.291  1   45.126 ? 130  LYS A CG  1 
ATOM   866  C  CD  . LYS A 1 138 ? -18.612 -7.792  12.415  1   52.154 ? 130  LYS A CD  1 
ATOM   867  C  CE  . LYS A 1 138 ? -19.89  -6.982  12.631  1   55.914 ? 130  LYS A CE  1 
ATOM   868  N  NZ  . LYS A 1 138 ? -20.3   -6.605  14.017  1   36.801 ? 130  LYS A NZ  1 
ATOM   869  N  N   . SER A 1 139 ? -16.972 -7.843  16.106  1   23.843 ? 131  SER A N   1 
ATOM   870  C  CA  . SER A 1 139 ? -17.617 -7.521  17.378  1   22.192 ? 131  SER A CA  1 
ATOM   871  C  C   . SER A 1 139 ? -19.012 -8.163  17.376  1   18.881 ? 131  SER A C   1 
ATOM   872  O  O   . SER A 1 139 ? -19.729 -8.082  16.371  1   22.108 ? 131  SER A O   1 
ATOM   873  C  CB  . SER A 1 139 ? -17.716 -6.029  17.47   1   21.986 ? 131  SER A CB  1 
ATOM   874  O  OG  . SER A 1 139 ? -18.489 -5.606  18.584  1   20.457 ? 131  SER A OG  1 
ATOM   875  N  N   . MET A 1 140 ? -19.387 -8.797  18.494  1   19.6   ? 132  MET A N   1 
ATOM   876  C  CA  . MET A 1 140 ? -20.682 -9.454  18.642  1   20.828 ? 132  MET A CA  1 
ATOM   877  C  C   . MET A 1 140 ? -21.284 -9.08   20.005  1   23.052 ? 132  MET A C   1 
ATOM   878  O  O   . MET A 1 140 ? -22.304 -9.637  20.391  1   21.753 ? 132  MET A O   1 
ATOM   879  C  CB  . MET A 1 140 ? -20.499 -10.965 18.482  1   22.361 ? 132  MET A CB  1 
ATOM   880  C  CG  . MET A 1 140 ? -20.346 -11.332 16.956  1   28.508 ? 132  MET A CG  1 
ATOM   881  S  SD  . MET A 1 140 ? -19.939 -13.057 16.757  1   34.684 ? 132  MET A SD  1 
ATOM   882  C  CE  . MET A 1 140 ? -21.653 -13.629 16.717  1   30.84  ? 132  MET A CE  1 
ATOM   883  N  N   . TYR A 1 141 ? -20.667 -8.11   20.699  1   19.565 ? 133  TYR A N   1 
ATOM   884  C  CA  . TYR A 1 141 ? -21.144 -7.733  22.025  1   21.158 ? 133  TYR A CA  1 
ATOM   885  C  C   . TYR A 1 141 ? -21.395 -6.236  22.039  1   20.97  ? 133  TYR A C   1 
ATOM   886  O  O   . TYR A 1 141 ? -20.672 -5.499  21.337  1   21.17  ? 133  TYR A O   1 
ATOM   887  C  CB  . TYR A 1 141 ? -20.168 -8.138  23.127  1   18.419 ? 133  TYR A CB  1 
ATOM   888  C  CG  . TYR A 1 141 ? -20.088 -9.65   23.324  1   17.624 ? 133  TYR A CG  1 
ATOM   889  C  CD1 . TYR A 1 141 ? -19.357 -10.482 22.456  1   19.878 ? 133  TYR A CD1 1 
ATOM   890  C  CD2 . TYR A 1 141 ? -20.813 -10.258 24.356  1   19.638 ? 133  TYR A CD2 1 
ATOM   891  C  CE1 . TYR A 1 141 ? -19.336 -11.866 22.637  1   21.408 ? 133  TYR A CE1 1 
ATOM   892  C  CE2 . TYR A 1 141 ? -20.813 -11.649 24.525  1   20.205 ? 133  TYR A CE2 1 
ATOM   893  C  CZ  . TYR A 1 141 ? -20.036 -12.444 23.702  1   20.339 ? 133  TYR A CZ  1 
ATOM   894  O  OH  . TYR A 1 141 ? -19.953 -13.808 23.849  1   21.269 ? 133  TYR A OH  1 
ATOM   895  N  N   . GLY A 1 142 ? -22.423 -5.831  22.803  1   18.434 ? 134  GLY A N   1 
ATOM   896  C  CA  . GLY A 1 142 ? -22.786 -4.415  22.88   1   18.634 ? 134  GLY A CA  1 
ATOM   897  C  C   . GLY A 1 142 ? -22.294 -3.784  24.168  1   19.125 ? 134  GLY A C   1 
ATOM   898  O  O   . GLY A 1 142 ? -21.085 -3.744  24.478  1   20.378 ? 134  GLY A O   1 
ATOM   899  N  N   . LEU A 1 143 ? -23.237 -3.158  24.844  1   17.962 ? 135  LEU A N   1 
ATOM   900  C  CA  . LEU A 1 143 ? -22.961 -2.341  26.019  1   19.257 ? 135  LEU A CA  1 
ATOM   901  C  C   . LEU A 1 143 ? -22.46  -3.218  27.168  1   19.745 ? 135  LEU A C   1 
ATOM   902  O  O   . LEU A 1 143 ? -22.849 -4.379  27.294  1   18.597 ? 135  LEU A O   1 
ATOM   903  C  CB  . LEU A 1 143 ? -24.189 -1.555  26.5    1   20.073 ? 135  LEU A CB  1 
ATOM   904  C  CG  . LEU A 1 143 ? -24.824 -0.607  25.47   1   20.788 ? 135  LEU A CG  1 
ATOM   905  C  CD1 . LEU A 1 143 ? -25.997 0.045   26.268  1   22.862 ? 135  LEU A CD1 1 
ATOM   906  C  CD2 . LEU A 1 143 ? -23.774 0.419   24.97   1   18.8   ? 135  LEU A CD2 1 
ATOM   907  N  N   . TYR A 1 144 ? -21.634 -2.594  28.007  1   18.458 ? 136  TYR A N   1 
ATOM   908  C  CA  . TYR A 1 144 ? -21.165 -3.202  29.242  1   19.001 ? 136  TYR A CA  1 
ATOM   909  C  C   . TYR A 1 144 ? -22.324 -3.845  29.991  1   18.455 ? 136  TYR A C   1 
ATOM   910  O  O   . TYR A 1 144 ? -23.294 -3.174  30.358  1   18.585 ? 136  TYR A O   1 
ATOM   911  C  CB  . TYR A 1 144 ? -20.541 -2.087  30.093  1   19.527 ? 136  TYR A CB  1 
ATOM   912  C  CG  . TYR A 1 144 ? -20.016 -2.554  31.449  1   18.89  ? 136  TYR A CG  1 
ATOM   913  C  CD1 . TYR A 1 144 ? -18.803 -3.261  31.549  1   19.084 ? 136  TYR A CD1 1 
ATOM   914  C  CD2 . TYR A 1 144 ? -20.722 -2.275  32.626  1   20.558 ? 136  TYR A CD2 1 
ATOM   915  C  CE1 . TYR A 1 144 ? -18.299 -3.663  32.783  1   18.844 ? 136  TYR A CE1 1 
ATOM   916  C  CE2 . TYR A 1 144 ? -20.218 -2.66   33.866  1   21.4   ? 136  TYR A CE2 1 
ATOM   917  C  CZ  . TYR A 1 144 ? -19.017 -3.364  33.932  1   21.898 ? 136  TYR A CZ  1 
ATOM   918  O  OH  . TYR A 1 144 ? -18.491 -3.751  35.135  1   21.87  ? 136  TYR A OH  1 
ATOM   919  N  N   . ARG A 1 145 ? -22.173 -5.165  30.253  1   17.607 ? 137  ARG A N   1 
ATOM   920  C  CA  . ARG A 1 145 ? -23.114 -5.966  31.044  1   17.605 ? 137  ARG A CA  1 
ATOM   921  C  C   . ARG A 1 145 ? -24.558 -5.852  30.544  1   18.561 ? 137  ARG A C   1 
ATOM   922  O  O   . ARG A 1 145 ? -25.458 -5.904  31.366  1   21.49  ? 137  ARG A O   1 
ATOM   923  C  CB  . ARG A 1 145 ? -23.013 -5.575  32.542  1   15.904 ? 137  ARG A CB  1 
ATOM   924  C  CG  . ARG A 1 145 ? -21.608 -5.862  33.059  1   19.279 ? 137  ARG A CG  1 
ATOM   925  C  CD  . ARG A 1 145 ? -21.648 -5.74   34.605  1   20.64  ? 137  ARG A CD  1 
ATOM   926  N  NE  . ARG A 1 145 ? -22.443 -6.841  35.163  1   19.664 ? 137  ARG A NE  1 
ATOM   927  C  CZ  . ARG A 1 145 ? -22.391 -7.25   36.43   1   20.484 ? 137  ARG A CZ  1 
ATOM   928  N  NH1 . ARG A 1 145 ? -21.636 -6.587  37.309  1   19.66  ? 137  ARG A NH1 1 
ATOM   929  N  NH2 . ARG A 1 145 ? -22.985 -8.395  36.767  1   21.208 ? 137  ARG A NH2 1 
ATOM   930  N  N   . ASN A 1 146 ? -24.776 -5.725  29.22   1   18.023 ? 138  ASN A N   1 
ATOM   931  C  CA  . ASN A 1 146 ? -26.141 -5.686  28.731  1   19.646 ? 138  ASN A CA  1 
ATOM   932  C  C   . ASN A 1 146 ? -26.321 -6.697  27.602  1   20.33  ? 138  ASN A C   1 
ATOM   933  O  O   . ASN A 1 146 ? -26.216 -6.33   26.429  1   20.459 ? 138  ASN A O   1 
ATOM   934  C  CB  . ASN A 1 146 ? -26.594 -4.282  28.308  1   20.145 ? 138  ASN A CB  1 
ATOM   935  C  CG  . ASN A 1 146 ? -28.09  -4.318  28.028  1   22.226 ? 138  ASN A CG  1 
ATOM   936  O  OD1 . ASN A 1 146 ? -28.678 -5.411  28.075  1   21.938 ? 138  ASN A OD1 1 
ATOM   937  N  ND2 . ASN A 1 146 ? -28.708 -3.178  27.724  1   20.964 ? 138  ASN A ND2 1 
ATOM   938  N  N   . PRO A 1 147 ? -26.595 -7.986  27.914  1   21.804 ? 139  PRO A N   1 
ATOM   939  C  CA  . PRO A 1 147 ? -26.92  -8.998  26.916  1   19.931 ? 139  PRO A CA  1 
ATOM   940  C  C   . PRO A 1 147 ? -28.06  -8.671  25.935  1   20.287 ? 139  PRO A C   1 
ATOM   941  O  O   . PRO A 1 147 ? -28.089 -9.232  24.829  1   19.007 ? 139  PRO A O   1 
ATOM   942  C  CB  . PRO A 1 147 ? -27.318 -10.22  27.761  1   22.375 ? 139  PRO A CB  1 
ATOM   943  C  CG  . PRO A 1 147 ? -26.502 -10.01  29.049  1   21.803 ? 139  PRO A CG  1 
ATOM   944  C  CD  . PRO A 1 147 ? -26.526 -8.554  29.282  1   19.771 ? 139  PRO A CD  1 
ATOM   945  N  N   . TYR A 1 148 ? -28.976 -7.768  26.311  1   22.865 ? 140  TYR A N   1 
ATOM   946  C  CA  . TYR A 1 148 ? -30.028 -7.302  25.396  1   23.777 ? 140  TYR A CA  1 
ATOM   947  C  C   . TYR A 1 148 ? -29.451 -6.463  24.247  1   23.328 ? 140  TYR A C   1 
ATOM   948  O  O   . TYR A 1 148 ? -30.195 -6.042  23.36   1   23.599 ? 140  TYR A O   1 
ATOM   949  C  CB  . TYR A 1 148 ? -31.153 -6.558  26.135  1   19.919 ? 140  TYR A CB  1 
ATOM   950  C  CG  . TYR A 1 148 ? -31.772 -7.498  27.156  1   21.119 ? 140  TYR A CG  1 
ATOM   951  C  CD1 . TYR A 1 148 ? -32.691 -8.487  26.772  1   21.101 ? 140  TYR A CD1 1 
ATOM   952  C  CD2 . TYR A 1 148 ? -31.44  -7.395  28.513  1   21.43  ? 140  TYR A CD2 1 
ATOM   953  C  CE1 . TYR A 1 148 ? -33.233 -9.392  27.681  1   22.03  ? 140  TYR A CE1 1 
ATOM   954  C  CE2 . TYR A 1 148 ? -31.997 -8.271  29.437  1   22.319 ? 140  TYR A CE2 1 
ATOM   955  C  CZ  . TYR A 1 148 ? -32.862 -9.29   29.022  1   21.288 ? 140  TYR A CZ  1 
ATOM   956  O  OH  . TYR A 1 148 ? -33.355 -10.134 29.978  1   20.802 ? 140  TYR A OH  1 
ATOM   957  N  N   . THR A 1 149 ? -28.175 -6.063  24.346  1   18.806 ? 141  THR A N   1 
ATOM   958  C  CA  . THR A 1 149 ? -27.469 -5.386  23.272  1   20.602 ? 141  THR A CA  1 
ATOM   959  C  C   . THR A 1 149 ? -26.379 -6.255  22.635  1   19.477 ? 141  THR A C   1 
ATOM   960  O  O   . THR A 1 149 ? -25.605 -5.751  21.809  1   20.999 ? 141  THR A O   1 
ATOM   961  C  CB  . THR A 1 149 ? -26.9   -4.04   23.751  1   21.091 ? 141  THR A CB  1 
ATOM   962  O  OG1 . THR A 1 149 ? -25.885 -4.259  24.744  1   22.12  ? 141  THR A OG1 1 
ATOM   963  C  CG2 . THR A 1 149 ? -27.986 -3.128  24.323  1   22.591 ? 141  THR A CG2 1 
ATOM   964  N  N   . HIS A 1 150 ? -26.289 -7.546  22.981  1   20.711 ? 142  HIS A N   1 
ATOM   965  C  CA  . HIS A 1 150 ? -25.353 -8.431  22.331  1   21.553 ? 142  HIS A CA  1 
ATOM   966  C  C   . HIS A 1 150 ? -26.01  -9.076  21.119  1   22.429 ? 142  HIS A C   1 
ATOM   967  O  O   . HIS A 1 150 ? -27.252 -9.117  20.986  1   22.557 ? 142  HIS A O   1 
ATOM   968  C  CB  . HIS A 1 150 ? -24.803 -9.533  23.25   1   21.315 ? 142  HIS A CB  1 
ATOM   969  C  CG  . HIS A 1 150 ? -24.118 -9.025  24.49   1   22.028 ? 142  HIS A CG  1 
ATOM   970  N  ND1 . HIS A 1 150 ? -23.616 -7.742  24.59   1   20.69  ? 142  HIS A ND1 1 
ATOM   971  C  CD2 . HIS A 1 150 ? -23.91  -9.614  25.685  1   20.819 ? 142  HIS A CD2 1 
ATOM   972  C  CE1 . HIS A 1 150 ? -23.091 -7.576  25.821  1   22.09  ? 142  HIS A CE1 1 
ATOM   973  N  NE2 . HIS A 1 150 ? -23.26  -8.703  26.497  1   21.071 ? 142  HIS A NE2 1 
ATOM   974  N  N   . HIS A 1 151 ? -25.148 -9.617  20.267  1   23.084 ? 143  HIS A N   1 
ATOM   975  C  CA  . HIS A 1 151 ? -25.595 -10.383 19.111  1   22.696 ? 143  HIS A CA  1 
ATOM   976  C  C   . HIS A 1 151 ? -26.463 -11.551 19.594  1   23.494 ? 143  HIS A C   1 
ATOM   977  O  O   . HIS A 1 151 ? -26.145 -12.225 20.586  1   23.121 ? 143  HIS A O   1 
ATOM   978  C  CB  . HIS A 1 151 ? -24.372 -10.926 18.386  1   21.96  ? 143  HIS A CB  1 
ATOM   979  C  CG  . HIS A 1 151 ? -24.619 -11.589 17.096  1   19.669 ? 143  HIS A CG  1 
ATOM   980  N  ND1 . HIS A 1 151 ? -25.167 -12.839 16.988  1   22.124 ? 143  HIS A ND1 1 
ATOM   981  C  CD2 . HIS A 1 151 ? -24.266 -11.2   15.862  1   21.376 ? 143  HIS A CD2 1 
ATOM   982  C  CE1 . HIS A 1 151 ? -25.151 -13.204 15.7    1   24.013 ? 143  HIS A CE1 1 
ATOM   983  N  NE2 . HIS A 1 151 ? -24.613 -12.22  14.996  1   22.132 ? 143  HIS A NE2 1 
ATOM   984  N  N   . PRO A 1 152 ? -27.616 -11.808 18.933  1   21.993 ? 144  PRO A N   1 
ATOM   985  C  CA  . PRO A 1 152 ? -28.522 -12.888 19.325  1   23.948 ? 144  PRO A CA  1 
ATOM   986  C  C   . PRO A 1 152 ? -27.848 -14.231 19.611  1   24.644 ? 144  PRO A C   1 
ATOM   987  O  O   . PRO A 1 152 ? -28.193 -14.881 20.599  1   24.85  ? 144  PRO A O   1 
ATOM   988  C  CB  . PRO A 1 152 ? -29.442 -12.995 18.103  1   25.044 ? 144  PRO A CB  1 
ATOM   989  C  CG  . PRO A 1 152 ? -29.625 -11.518 17.807  1   23.942 ? 144  PRO A CG  1 
ATOM   990  C  CD  . PRO A 1 152 ? -28.182 -10.993 17.846  1   21.907 ? 144  PRO A CD  1 
ATOM   991  N  N   . CYS A 1 153 ? -26.833 -14.585 18.808  1   22.307 ? 145  CYS A N   1 
ATOM   992  C  CA  . CYS A 1 153 ? -26.176 -15.879 18.906  1   23.956 ? 145  CYS A CA  1 
ATOM   993  C  C   . CYS A 1 153 ? -25.312 -15.978 20.165  1   24.815 ? 145  CYS A C   1 
ATOM   994  O  O   . CYS A 1 153 ? -24.921 -17.091 20.51   1   27.847 ? 145  CYS A O   1 
ATOM   995  C  CB  . CYS A 1 153 ? -25.318 -16.181 17.68   1   29.834 ? 145  CYS A CB  1 
ATOM   996  S  SG  . CYS A 1 153 ? -26.28  -16.641 16.202  1   48.379 ? 145  CYS A SG  1 
ATOM   997  N  N   . VAL A 1 154 ? -24.983 -14.85  20.821  1   22.273 ? 146  VAL A N   1 
ATOM   998  C  CA  . VAL A 1 154 ? -24.102 -14.904 21.994  1   23.161 ? 146  VAL A CA  1 
ATOM   999  C  C   . VAL A 1 154 ? -24.794 -14.443 23.28   1   24.383 ? 146  VAL A C   1 
ATOM   1000 O  O   . VAL A 1 154 ? -24.122 -14.247 24.303  1   23.371 ? 146  VAL A O   1 
ATOM   1001 C  CB  . VAL A 1 154 ? -22.79  -14.11  21.764  1   24.898 ? 146  VAL A CB  1 
ATOM   1002 C  CG1 . VAL A 1 154 ? -22.049 -14.605 20.532  1   31.821 ? 146  VAL A CG1 1 
ATOM   1003 C  CG2 . VAL A 1 154 ? -22.989 -12.582 21.713  1   23.825 ? 146  VAL A CG2 1 
ATOM   1004 N  N   . ARG A 1 155 ? -26.12  -14.197 23.248  1   22.821 ? 147  ARG A N   1 
ATOM   1005 C  CA  . ARG A 1 155 ? -26.77  -13.603 24.413  1   22.202 ? 147  ARG A CA  1 
ATOM   1006 C  C   . ARG A 1 155 ? -26.648 -14.477 25.649  1   22.366 ? 147  ARG A C   1 
ATOM   1007 O  O   . ARG A 1 155 ? -26.599 -13.932 26.745  1   22.446 ? 147  ARG A O   1 
ATOM   1008 C  CB  . ARG A 1 155 ? -28.293 -13.389 24.303  1   25.166 ? 147  ARG A CB  1 
ATOM   1009 C  CG  . ARG A 1 155 ? -28.54  -12.213 23.39   1   33.209 ? 147  ARG A CG  1 
ATOM   1010 C  CD  . ARG A 1 155 ? -30.019 -11.75  23.493  1   34.277 ? 147  ARG A CD  1 
ATOM   1011 N  NE  . ARG A 1 155 ? -29.897 -10.719 22.447  1   35.757 ? 147  ARG A NE  1 
ATOM   1012 C  CZ  . ARG A 1 155 ? -30.487 -9.568  22.246  1   49.647 ? 147  ARG A CZ  1 
ATOM   1013 N  NH1 . ARG A 1 155 ? -31.678 -9.328  22.79   1   44.412 ? 147  ARG A NH1 1 
ATOM   1014 N  NH2 . ARG A 1 155 ? -29.931 -8.71   21.39   1   51.438 ? 147  ARG A NH2 1 
ATOM   1015 N  N   . GLN A 1 156 ? -26.621 -15.802 25.439  1   22.384 ? 148  GLN A N   1 
ATOM   1016 C  CA  . GLN A 1 156 ? -26.588 -16.751 26.536  1   25.24  ? 148  GLN A CA  1 
ATOM   1017 C  C   . GLN A 1 156 ? -25.166 -17.278 26.748  1   23.866 ? 148  GLN A C   1 
ATOM   1018 O  O   . GLN A 1 156 ? -24.986 -18.356 27.289  1   27.305 ? 148  GLN A O   1 
ATOM   1019 C  CB  . GLN A 1 156 ? -27.633 -17.848 26.311  1   28.375 ? 148  GLN A CB  1 
ATOM   1020 C  CG  . GLN A 1 156 ? -28.342 -18.211 27.62   1   34.673 ? 148  GLN A CG  1 
ATOM   1021 C  CD  . GLN A 1 156 ? -29.584 -19.078 27.423  1   40.214 ? 148  GLN A CD  1 
ATOM   1022 O  OE1 . GLN A 1 156 ? -30.181 -19.132 26.348  1   36.35  ? 148  GLN A OE1 1 
ATOM   1023 N  NE2 . GLN A 1 156 ? -30.027 -19.739 28.479  1   42.218 ? 148  GLN A NE2 1 
ATOM   1024 N  N   . THR A 1 157 ? -24.172 -16.447 26.442  1   22.371 ? 149  THR A N   1 
ATOM   1025 C  CA  . THR A 1 157 ? -22.773 -16.762 26.747  1   19.58  ? 149  THR A CA  1 
ATOM   1026 C  C   . THR A 1 157 ? -22.427 -16.056 28.065  1   19.299 ? 149  THR A C   1 
ATOM   1027 O  O   . THR A 1 157 ? -23.124 -15.132 28.5    1   21.907 ? 149  THR A O   1 
ATOM   1028 C  CB  . THR A 1 157 ? -21.805 -16.292 25.649  1   18.831 ? 149  THR A CB  1 
ATOM   1029 O  OG1 . THR A 1 157 ? -21.949 -14.866 25.514  1   21.051 ? 149  THR A OG1 1 
ATOM   1030 C  CG2 . THR A 1 157 ? -22.004 -17.028 24.324  1   20.481 ? 149  THR A CG2 1 
ATOM   1031 N  N   . VAL A 1 158 ? -21.299 -16.462 28.651  1   20.117 ? 150  VAL A N   1 
ATOM   1032 C  CA  . VAL A 1 158 ? -20.628 -15.624 29.638  1   20.128 ? 150  VAL A CA  1 
ATOM   1033 C  C   . VAL A 1 158 ? -19.98  -14.454 28.884  1   20.811 ? 150  VAL A C   1 
ATOM   1034 O  O   . VAL A 1 158 ? -19.22  -14.674 27.947  1   20.978 ? 150  VAL A O   1 
ATOM   1035 C  CB  . VAL A 1 158 ? -19.622 -16.511 30.4    1   21.586 ? 150  VAL A CB  1 
ATOM   1036 C  CG1 . VAL A 1 158 ? -18.572 -15.68  31.138  1   19.762 ? 150  VAL A CG1 1 
ATOM   1037 C  CG2 . VAL A 1 158 ? -20.372 -17.399 31.385  1   22.688 ? 150  VAL A CG2 1 
ATOM   1038 N  N   . GLU A 1 159 ? -20.356 -13.224 29.284  1   19.202 ? 151  GLU A N   1 
ATOM   1039 C  CA  . GLU A 1 159 ? -20.03  -12.03  28.527  1   17.932 ? 151  GLU A CA  1 
ATOM   1040 C  C   . GLU A 1 159 ? -18.791 -11.331 29.11   1   19.911 ? 151  GLU A C   1 
ATOM   1041 O  O   . GLU A 1 159 ? -18.374 -10.296 28.6    1   20.243 ? 151  GLU A O   1 
ATOM   1042 C  CB  . GLU A 1 159 ? -21.223 -11.079 28.427  1   20.682 ? 151  GLU A CB  1 
ATOM   1043 C  CG  . GLU A 1 159 ? -21.778 -10.766 29.815  1   20.801 ? 151  GLU A CG  1 
ATOM   1044 C  CD  . GLU A 1 159 ? -22.295 -9.383  30.09   1   27.241 ? 151  GLU A CD  1 
ATOM   1045 O  OE1 . GLU A 1 159 ? -22.536 -8.624  29.118  1   26.019 ? 151  GLU A OE1 1 
ATOM   1046 O  OE2 . GLU A 1 159 ? -22.458 -9.111  31.318  1   30.443 ? 151  GLU A OE2 1 
ATOM   1047 N  N   . SER A 1 160 ? -18.241 -11.874 30.207  1   17.638 ? 152  SER A N   1 
ATOM   1048 C  CA  . SER A 1 160 ? -17.039 -11.328 30.842  1   18.6   ? 152  SER A CA  1 
ATOM   1049 C  C   . SER A 1 160 ? -15.874 -11.195 29.864  1   19.837 ? 152  SER A C   1 
ATOM   1050 O  O   . SER A 1 160 ? -15.569 -12.136 29.133  1   20.034 ? 152  SER A O   1 
ATOM   1051 C  CB  . SER A 1 160 ? -16.644 -12.199 32.005  1   18.456 ? 152  SER A CB  1 
ATOM   1052 O  OG  . SER A 1 160 ? -15.358 -11.784 32.45   1   20.286 ? 152  SER A OG  1 
ATOM   1053 N  N   . THR A 1 161 ? -15.17  -10.045 29.922  1   19.306 ? 153  THR A N   1 
ATOM   1054 C  CA  . THR A 1 161 ? -13.905 -9.867  29.207  1   18.226 ? 153  THR A CA  1 
ATOM   1055 C  C   . THR A 1 161 ? -12.707 -10.106 30.136  1   18.057 ? 153  THR A C   1 
ATOM   1056 O  O   . THR A 1 161 ? -11.577 -9.884  29.735  1   18.394 ? 153  THR A O   1 
ATOM   1057 C  CB  . THR A 1 161 ? -13.821 -8.486  28.559  1   20.279 ? 153  THR A CB  1 
ATOM   1058 O  OG1 . THR A 1 161 ? -14.175 -7.567  29.591  1   18.637 ? 153  THR A OG1 1 
ATOM   1059 C  CG2 . THR A 1 161 ? -14.804 -8.397  27.398  1   18.341 ? 153  THR A CG2 1 
ATOM   1060 N  N   . ALA A 1 162 ? -12.966 -10.475 31.396  1   16.941 ? 154  ALA A N   1 
ATOM   1061 C  CA  . ALA A 1 162 ? -11.909 -10.929 32.308  1   17.969 ? 154  ALA A CA  1 
ATOM   1062 C  C   . ALA A 1 162 ? -10.733 -9.954  32.254  1   18.61  ? 154  ALA A C   1 
ATOM   1063 O  O   . ALA A 1 162 ? -9.618  -10.372 31.977  1   18.78  ? 154  ALA A O   1 
ATOM   1064 C  CB  . ALA A 1 162 ? -11.424 -12.351 31.955  1   20.064 ? 154  ALA A CB  1 
ATOM   1065 N  N   . ASN A 1 163 ? -10.981 -8.678  32.603  1   18.655 ? 155  ASN A N   1 
ATOM   1066 C  CA  . ASN A 1 163 ? -10.017 -7.634  32.29   1   17.465 ? 155  ASN A CA  1 
ATOM   1067 C  C   . ASN A 1 163 ? -9.659  -6.747  33.47   1   18.802 ? 155  ASN A C   1 
ATOM   1068 O  O   . ASN A 1 163 ? -9.101  -5.695  33.199  1   18.707 ? 155  ASN A O   1 
ATOM   1069 C  CB  . ASN A 1 163 ? -10.543 -6.775  31.132  1   17.835 ? 155  ASN A CB  1 
ATOM   1070 C  CG  . ASN A 1 163 ? -11.775 -5.969  31.514  1   17.999 ? 155  ASN A CG  1 
ATOM   1071 O  OD1 . ASN A 1 163 ? -12.319 -6.127  32.621  1   17.987 ? 155  ASN A OD1 1 
ATOM   1072 N  ND2 . ASN A 1 163 ? -12.222 -5.085  30.611  1   16.799 ? 155  ASN A ND2 1 
ATOM   1073 N  N   . THR A 1 164 ? -9.997  -7.136  34.716  1   19.576 ? 156  THR A N   1 
ATOM   1074 C  CA  . THR A 1 164 ? -9.947  -6.21   35.851  1   19.631 ? 156  THR A CA  1 
ATOM   1075 C  C   . THR A 1 164 ? -8.79   -6.558  36.778  1   18.048 ? 156  THR A C   1 
ATOM   1076 O  O   . THR A 1 164 ? -8.054  -5.67   37.167  1   17.254 ? 156  THR A O   1 
ATOM   1077 C  CB  . THR A 1 164 ? -11.283 -6.271  36.635  1   25.017 ? 156  THR A CB  1 
ATOM   1078 O  OG1 . THR A 1 164 ? -12.258 -5.821  35.686  1   26.649 ? 156  THR A OG1 1 
ATOM   1079 C  CG2 . THR A 1 164 ? -11.262 -5.414  37.876  1   30.523 ? 156  THR A CG2 1 
ATOM   1080 N  N   . ASN A 1 165 ? -8.617  -7.832  37.146  1   19.282 ? 157  ASN A N   1 
ATOM   1081 C  CA  . ASN A 1 165 ? -7.603  -8.141  38.152  1   18.728 ? 157  ASN A CA  1 
ATOM   1082 C  C   . ASN A 1 165 ? -7.173  -9.593  38.011  1   17.784 ? 157  ASN A C   1 
ATOM   1083 O  O   . ASN A 1 165 ? -7.81   -10.377 37.314  1   18.465 ? 157  ASN A O   1 
ATOM   1084 C  CB  . ASN A 1 165 ? -8.173  -7.869  39.54   1   17.663 ? 157  ASN A CB  1 
ATOM   1085 C  CG  . ASN A 1 165 ? -7.143  -7.775  40.649  1   19.557 ? 157  ASN A CG  1 
ATOM   1086 O  OD1 . ASN A 1 165 ? -5.921  -7.772  40.427  1   17.92  ? 157  ASN A OD1 1 
ATOM   1087 N  ND2 . ASN A 1 165 ? -7.634  -7.692  41.873  1   19.604 ? 157  ASN A ND2 1 
ATOM   1088 N  N   . VAL A 1 166 ? -6.066  -9.942  38.679  1   17.068 ? 158  VAL A N   1 
ATOM   1089 C  CA  . VAL A 1 166 ? -5.518  -11.283 38.64   1   17.582 ? 158  VAL A CA  1 
ATOM   1090 C  C   . VAL A 1 166 ? -5.205  -11.726 40.067  1   19.135 ? 158  VAL A C   1 
ATOM   1091 O  O   . VAL A 1 166 ? -5.057  -10.894 40.946  1   18.553 ? 158  VAL A O   1 
ATOM   1092 C  CB  . VAL A 1 166 ? -4.279  -11.431 37.736  1   18.102 ? 158  VAL A CB  1 
ATOM   1093 C  CG1 . VAL A 1 166 ? -4.621  -11.038 36.282  1   17.651 ? 158  VAL A CG1 1 
ATOM   1094 C  CG2 . VAL A 1 166 ? -3.094  -10.59  38.243  1   18.789 ? 158  VAL A CG2 1 
ATOM   1095 N  N   . VAL A 1 167 ? -5.11   -13.06  40.257  1   19.029 ? 159  VAL A N   1 
ATOM   1096 C  CA  . VAL A 1 167 ? -4.729  -13.617 41.547  1   19.758 ? 159  VAL A CA  1 
ATOM   1097 C  C   . VAL A 1 167 ? -4.109  -14.989 41.284  1   20.202 ? 159  VAL A C   1 
ATOM   1098 O  O   . VAL A 1 167 ? -4.481  -15.671 40.328  1   20.69  ? 159  VAL A O   1 
ATOM   1099 C  CB  . VAL A 1 167 ? -5.925  -13.696 42.519  1   20.57  ? 159  VAL A CB  1 
ATOM   1100 C  CG1 . VAL A 1 167 ? -7.014  -14.678 42.062  1   19.547 ? 159  VAL A CG1 1 
ATOM   1101 C  CG2 . VAL A 1 167 ? -5.466  -14.033 43.959  1   23.28  ? 159  VAL A CG2 1 
ATOM   1102 N  N   . MET A 1 168 ? -3.12   -15.36  42.119  1   20.6   ? 160  MET A N   1 
ATOM   1103 C  CA  . MET A 1 168 ? -2.626  -16.732 42.183  1   20.48  ? 160  MET A CA  1 
ATOM   1104 C  C   . MET A 1 168 ? -3.134  -17.313 43.509  1   20.426 ? 160  MET A C   1 
ATOM   1105 O  O   . MET A 1 168 ? -2.795  -16.814 44.582  1   20.766 ? 160  MET A O   1 
ATOM   1106 C  CB  . MET A 1 168 ? -1.098  -16.733 42.221  1   21.254 ? 160  MET A CB  1 
ATOM   1107 C  CG  . MET A 1 168 ? -0.515  -18.163 42.308  1   21.954 ? 160  MET A CG  1 
ATOM   1108 S  SD  . MET A 1 168 ? -0.674  -19.126 40.798  1   28.538 ? 160  MET A SD  1 
ATOM   1109 C  CE  . MET A 1 168 ? 0.588   -18.347 39.794  1   26.285 ? 160  MET A CE  1 
ATOM   1110 N  N   . HIS A 1 169 ? -4      -18.342 43.405  1   22.353 ? 161  HIS A N   1 
ATOM   1111 C  CA  . HIS A 1 169 ? -4.579  -18.945 44.601  1   20.769 ? 161  HIS A CA  1 
ATOM   1112 C  C   . HIS A 1 169 ? -4.643  -20.455 44.39   1   22.994 ? 161  HIS A C   1 
ATOM   1113 O  O   . HIS A 1 169 ? -5.079  -20.91  43.333  1   23.19  ? 161  HIS A O   1 
ATOM   1114 C  CB  . HIS A 1 169 ? -5.975  -18.367 44.885  1   22.241 ? 161  HIS A CB  1 
ATOM   1115 C  CG  . HIS A 1 169 ? -6.543  -19.015 46.112  1   21.192 ? 161  HIS A CG  1 
ATOM   1116 N  ND1 . HIS A 1 169 ? -6.053  -18.662 47.352  1   21.789 ? 161  HIS A ND1 1 
ATOM   1117 C  CD2 . HIS A 1 169 ? -7.424  -20.02  46.289  1   21.588 ? 161  HIS A CD2 1 
ATOM   1118 C  CE1 . HIS A 1 169 ? -6.626  -19.426 48.29   1   21.503 ? 161  HIS A CE1 1 
ATOM   1119 N  NE2 . HIS A 1 169 ? -7.47   -20.269 47.68   1   21.359 ? 161  HIS A NE2 1 
ATOM   1120 N  N   . ALA A 1 170 ? -4.175  -21.228 45.395  1   25.407 ? 162  ALA A N   1 
ATOM   1121 C  CA  . ALA A 1 170 ? -4.223  -22.694 45.339  1   26.154 ? 162  ALA A CA  1 
ATOM   1122 C  C   . ALA A 1 170 ? -3.561  -23.202 44.062  1   24.275 ? 162  ALA A C   1 
ATOM   1123 O  O   . ALA A 1 170 ? -4.067  -24.121 43.436  1   26.604 ? 162  ALA A O   1 
ATOM   1124 C  CB  . ALA A 1 170 ? -5.668  -23.167 45.45   1   23.345 ? 162  ALA A CB  1 
ATOM   1125 N  N   . GLY A 1 171 ? -2.436  -22.569 43.688  1   27.428 ? 163  GLY A N   1 
ATOM   1126 C  CA  . GLY A 1 171 ? -1.62   -22.924 42.523  1   25.396 ? 163  GLY A CA  1 
ATOM   1127 C  C   . GLY A 1 171 ? -2.279  -22.628 41.176  1   25.007 ? 163  GLY A C   1 
ATOM   1128 O  O   . GLY A 1 171 ? -1.803  -23.122 40.156  1   23.514 ? 163  GLY A O   1 
ATOM   1129 N  N   . ARG A 1 172 ? -3.36   -21.825 41.167  1   23.264 ? 164  ARG A N   1 
ATOM   1130 C  CA  . ARG A 1 172 ? -4.041  -21.505 39.921  1   23.381 ? 164  ARG A CA  1 
ATOM   1131 C  C   . ARG A 1 172 ? -3.983  -19.989 39.718  1   23.568 ? 164  ARG A C   1 
ATOM   1132 O  O   . ARG A 1 172 ? -4.181  -19.23  40.67   1   20.617 ? 164  ARG A O   1 
ATOM   1133 C  CB  . ARG A 1 172 ? -5.504  -21.936 39.976  1   22.361 ? 164  ARG A CB  1 
ATOM   1134 C  CG  . ARG A 1 172 ? -5.729  -23.397 40.329  1   29.155 ? 164  ARG A CG  1 
ATOM   1135 C  CD  . ARG A 1 172 ? -7.21   -23.58  40.089  1   35.089 ? 164  ARG A CD  1 
ATOM   1136 N  NE  . ARG A 1 172 ? -7.55   -24.981 40.346  1   38.288 ? 164  ARG A NE  1 
ATOM   1137 C  CZ  . ARG A 1 172 ? -7.744  -25.915 39.448  1   39.626 ? 164  ARG A CZ  1 
ATOM   1138 N  NH1 . ARG A 1 172 ? -7.713  -25.647 38.147  1   33.965 ? 164  ARG A NH1 1 
ATOM   1139 N  NH2 . ARG A 1 172 ? -8.002  -27.141 39.89   1   43.831 ? 164  ARG A NH2 1 
ATOM   1140 N  N   . PHE A 1 173 ? -3.696  -19.589 38.468  1   20.083 ? 165  PHE A N   1 
ATOM   1141 C  CA  . PHE A 1 173 ? -3.577  -18.183 38.128  1   20.091 ? 165  PHE A CA  1 
ATOM   1142 C  C   . PHE A 1 173 ? -4.87   -17.766 37.425  1   19.655 ? 165  PHE A C   1 
ATOM   1143 O  O   . PHE A 1 173 ? -5.256  -18.395 36.446  1   20.776 ? 165  PHE A O   1 
ATOM   1144 C  CB  . PHE A 1 173 ? -2.312  -17.985 37.268  1   20.934 ? 165  PHE A CB  1 
ATOM   1145 C  CG  . PHE A 1 173 ? -2.151  -16.538 36.811  1   21.21  ? 165  PHE A CG  1 
ATOM   1146 C  CD1 . PHE A 1 173 ? -1.863  -15.542 37.748  1   22.665 ? 165  PHE A CD1 1 
ATOM   1147 C  CD2 . PHE A 1 173 ? -2.341  -16.168 35.479  1   23.75  ? 165  PHE A CD2 1 
ATOM   1148 C  CE1 . PHE A 1 173 ? -1.725  -14.207 37.379  1   24.182 ? 165  PHE A CE1 1 
ATOM   1149 C  CE2 . PHE A 1 173 ? -2.203  -14.811 35.089  1   23.894 ? 165  PHE A CE2 1 
ATOM   1150 C  CZ  . PHE A 1 173 ? -1.89   -13.838 36.048  1   22.204 ? 165  PHE A CZ  1 
ATOM   1151 N  N   . LEU A 1 174 ? -5.524  -16.727 37.954  1   19.073 ? 166  LEU A N   1 
ATOM   1152 C  CA  . LEU A 1 174 ? -6.878  -16.384 37.505  1   21.154 ? 166  LEU A CA  1 
ATOM   1153 C  C   . LEU A 1 174 ? -6.937  -14.968 36.973  1   21.253 ? 166  LEU A C   1 
ATOM   1154 O  O   . LEU A 1 174 ? -6.354  -14.095 37.611  1   21.817 ? 166  LEU A O   1 
ATOM   1155 C  CB  . LEU A 1 174 ? -7.843  -16.431 38.68   1   20.521 ? 166  LEU A CB  1 
ATOM   1156 C  CG  . LEU A 1 174 ? -8.457  -17.78  39.07   1   29.447 ? 166  LEU A CG  1 
ATOM   1157 C  CD1 . LEU A 1 174 ? -7.553  -18.92  39.125  1   25.751 ? 166  LEU A CD1 1 
ATOM   1158 C  CD2 . LEU A 1 174 ? -9.218  -17.65  40.386  1   27.444 ? 166  LEU A CD2 1 
ATOM   1159 N  N   . ALA A 1 175 ? -7.7    -14.757 35.871  1   20.447 ? 167  ALA A N   1 
ATOM   1160 C  CA  . ALA A 1 175 ? -8.073  -13.414 35.416  1   21.616 ? 167  ALA A CA  1 
ATOM   1161 C  C   . ALA A 1 175 ? -9.556  -13.231 35.744  1   19.648 ? 167  ALA A C   1 
ATOM   1162 O  O   . ALA A 1 175 ? -10.354 -14.163 35.535  1   21.102 ? 167  ALA A O   1 
ATOM   1163 C  CB  . ALA A 1 175 ? -7.875  -13.297 33.904  1   18.604 ? 167  ALA A CB  1 
ATOM   1164 N  N   . MET A 1 176 ? -9.911  -12.043 36.275  1   18.07  ? 168  MET A N   1 
ATOM   1165 C  CA  . MET A 1 176 ? -11.201 -11.834 36.931  1   17.944 ? 168  MET A CA  1 
ATOM   1166 C  C   . MET A 1 176 ? -11.885 -10.586 36.367  1   18.898 ? 168  MET A C   1 
ATOM   1167 O  O   . MET A 1 176 ? -11.24  -9.632  35.972  1   17.781 ? 168  MET A O   1 
ATOM   1168 C  CB  . MET A 1 176 ? -10.999 -11.623 38.439  1   17.666 ? 168  MET A CB  1 
ATOM   1169 C  CG  . MET A 1 176 ? -10.317 -12.848 39.068  1   18.568 ? 168  MET A CG  1 
ATOM   1170 S  SD  . MET A 1 176 ? -10.038 -12.612 40.838  1   20.922 ? 168  MET A SD  1 
ATOM   1171 C  CE  . MET A 1 176 ? -8.605  -11.505 40.804  1   18.672 ? 168  MET A CE  1 
ATOM   1172 N  N   . LYS A 1 177 ? -13.202 -10.662 36.277  1   19.487 ? 169  LYS A N   1 
ATOM   1173 C  CA  . LYS A 1 177 ? -14.078 -9.503  36.059  1   17.161 ? 169  LYS A CA  1 
ATOM   1174 C  C   . LYS A 1 177 ? -15.398 -9.875  36.736  1   17.884 ? 169  LYS A C   1 
ATOM   1175 O  O   . LYS A 1 177 ? -15.864 -11     36.601  1   19.492 ? 169  LYS A O   1 
ATOM   1176 C  CB  . LYS A 1 177 ? -14.211 -9.222  34.546  1   16.083 ? 169  LYS A CB  1 
ATOM   1177 C  CG  . LYS A 1 177 ? -15.004 -7.887  34.33   1   15.541 ? 169  LYS A CG  1 
ATOM   1178 C  CD  . LYS A 1 177 ? -15.194 -7.766  32.794  1   16.107 ? 169  LYS A CD  1 
ATOM   1179 C  CE  . LYS A 1 177 ? -15.844 -6.423  32.45   1   19.141 ? 169  LYS A CE  1 
ATOM   1180 N  NZ  . LYS A 1 177 ? -14.984 -5.282  32.888  1   18.599 ? 169  LYS A NZ  1 
ATOM   1181 N  N   . GLU A 1 178 ? -16.022 -8.902  37.398  1   17.945 ? 170  GLU A N   1 
ATOM   1182 C  CA  . GLU A 1 178 ? -17.069 -9.167  38.372  1   16.793 ? 170  GLU A CA  1 
ATOM   1183 C  C   . GLU A 1 178 ? -18.371 -9.655  37.749  1   17.301 ? 170  GLU A C   1 
ATOM   1184 O  O   . GLU A 1 178 ? -19.279 -9.996  38.526  1   19.761 ? 170  GLU A O   1 
ATOM   1185 C  CB  . GLU A 1 178 ? -17.291 -7.918  39.221  1   19.738 ? 170  GLU A CB  1 
ATOM   1186 C  CG  . GLU A 1 178 ? -17.907 -6.73   38.473  1   18.86  ? 170  GLU A CG  1 
ATOM   1187 C  CD  . GLU A 1 178 ? -17.474 -5.487  39.246  1   23.156 ? 170  GLU A CD  1 
ATOM   1188 O  OE1 . GLU A 1 178 ? -16.277 -5.114  39.236  1   23.247 ? 170  GLU A OE1 1 
ATOM   1189 O  OE2 . GLU A 1 178 ? -18.34  -4.877  39.898  1   23.67  ? 170  GLU A OE2 1 
ATOM   1190 N  N   . ASN A 1 179 ? -18.504 -9.606  36.395  1   17.763 ? 171  ASN A N   1 
ATOM   1191 C  CA  . ASN A 1 179 ? -19.733 -10.087 35.755  1   19.554 ? 171  ASN A CA  1 
ATOM   1192 C  C   . ASN A 1 179 ? -19.656 -11.568 35.358  1   20.472 ? 171  ASN A C   1 
ATOM   1193 O  O   . ASN A 1 179 ? -20.538 -12.078 34.658  1   21.476 ? 171  ASN A O   1 
ATOM   1194 C  CB  . ASN A 1 179 ? -20.145 -9.21   34.56   1   18.604 ? 171  ASN A CB  1 
ATOM   1195 C  CG  . ASN A 1 179 ? -19.106 -9.158  33.472  1   22.871 ? 171  ASN A CG  1 
ATOM   1196 O  OD1 . ASN A 1 179 ? -17.916 -9.406  33.713  1   19.281 ? 171  ASN A OD1 1 
ATOM   1197 N  ND2 . ASN A 1 179 ? -19.575 -8.884  32.26   1   20.488 ? 171  ASN A ND2 1 
ATOM   1198 N  N   . GLY A 1 180 ? -18.607 -12.286 35.776  1   20.864 ? 172  GLY A N   1 
ATOM   1199 C  CA  . GLY A 1 180 ? -18.573 -13.741 35.569  1   18.383 ? 172  GLY A CA  1 
ATOM   1200 C  C   . GLY A 1 180 ? -17.612 -14.392 36.565  1   20.29  ? 172  GLY A C   1 
ATOM   1201 O  O   . GLY A 1 180 ? -16.969 -13.695 37.348  1   18.943 ? 172  GLY A O   1 
ATOM   1202 N  N   . ASN A 1 181 ? -17.542 -15.732 36.558  1   20.361 ? 173  ASN A N   1 
ATOM   1203 C  CA  . ASN A 1 181 ? -16.456 -16.379 37.273  1   21.382 ? 173  ASN A CA  1 
ATOM   1204 C  C   . ASN A 1 181 ? -15.112 -16.142 36.553  1   19.288 ? 173  ASN A C   1 
ATOM   1205 O  O   . ASN A 1 181 ? -15.071 -15.678 35.419  1   20.975 ? 173  ASN A O   1 
ATOM   1206 C  CB  . ASN A 1 181 ? -16.766 -17.857 37.494  1   18.55  ? 173  ASN A CB  1 
ATOM   1207 C  CG  . ASN A 1 181 ? -17.64  -17.991 38.723  1   20.103 ? 173  ASN A CG  1 
ATOM   1208 O  OD1 . ASN A 1 181 ? -17.171 -17.716 39.832  1   20.052 ? 173  ASN A OD1 1 
ATOM   1209 N  ND2 . ASN A 1 181 ? -18.912 -18.302 38.545  1   21.042 ? 173  ASN A ND2 1 
ATOM   1210 N  N   . ALA A 1 182 ? -14.021 -16.516 37.223  1   19.224 ? 174  ALA A N   1 
ATOM   1211 C  CA  . ALA A 1 182 ? -12.672 -16.293 36.735  1   21.506 ? 174  ALA A CA  1 
ATOM   1212 C  C   . ALA A 1 182 ? -12.373 -17.218 35.559  1   21.908 ? 174  ALA A C   1 
ATOM   1213 O  O   . ALA A 1 182 ? -12.907 -18.338 35.482  1   19.768 ? 174  ALA A O   1 
ATOM   1214 C  CB  . ALA A 1 182 ? -11.655 -16.528 37.857  1   18.828 ? 174  ALA A CB  1 
ATOM   1215 N  N   . TYR A 1 183 ? -11.456 -16.76  34.707  1   19.089 ? 175  TYR A N   1 
ATOM   1216 C  CA  . TYR A 1 183 ? -10.803 -17.677 33.792  1   19.927 ? 175  TYR A CA  1 
ATOM   1217 C  C   . TYR A 1 183 ? -9.389  -17.993 34.305  1   21.13  ? 175  TYR A C   1 
ATOM   1218 O  O   . TYR A 1 183 ? -8.672  -17.117 34.734  1   22.35  ? 175  TYR A O   1 
ATOM   1219 C  CB  . TYR A 1 183 ? -10.729 -17.079 32.383  1   19.468 ? 175  TYR A CB  1 
ATOM   1220 C  CG  . TYR A 1 183 ? -12.079 -16.991 31.653  1   18.816 ? 175  TYR A CG  1 
ATOM   1221 C  CD1 . TYR A 1 183 ? -12.942 -15.902 31.812  1   19.669 ? 175  TYR A CD1 1 
ATOM   1222 C  CD2 . TYR A 1 183 ? -12.441 -17.991 30.735  1   19.636 ? 175  TYR A CD2 1 
ATOM   1223 C  CE1 . TYR A 1 183 ? -14.127 -15.812 31.082  1   18.873 ? 175  TYR A CE1 1 
ATOM   1224 C  CE2 . TYR A 1 183 ? -13.628 -17.917 30.006  1   18.45  ? 175  TYR A CE2 1 
ATOM   1225 C  CZ  . TYR A 1 183 ? -14.461 -16.825 30.186  1   19.204 ? 175  TYR A CZ  1 
ATOM   1226 O  OH  . TYR A 1 183 ? -15.589 -16.778 29.404  1   18.241 ? 175  TYR A OH  1 
ATOM   1227 N  N   . GLU A 1 184 ? -9      -19.257 34.237  1   18.632 ? 176  GLU A N   1 
ATOM   1228 C  CA  . GLU A 1 184 ? -7.676  -19.7   34.657  1   19.424 ? 176  GLU A CA  1 
ATOM   1229 C  C   . GLU A 1 184 ? -6.724  -19.645 33.463  1   19.956 ? 176  GLU A C   1 
ATOM   1230 O  O   . GLU A 1 184 ? -7.089  -19.951 32.333  1   21.505 ? 176  GLU A O   1 
ATOM   1231 C  CB  . GLU A 1 184 ? -7.711  -21.122 35.214  1   20.31  ? 176  GLU A CB  1 
ATOM   1232 C  CG  . GLU A 1 184 ? -6.312  -21.587 35.654  1   20.707 ? 176  GLU A CG  1 
ATOM   1233 C  CD  . GLU A 1 184 ? -6.281  -22.942 36.327  1   25.499 ? 176  GLU A CD  1 
ATOM   1234 O  OE1 . GLU A 1 184 ? -7.348  -23.563 36.412  1   27.107 ? 176  GLU A OE1 1 
ATOM   1235 O  OE2 . GLU A 1 184 ? -5.166  -23.345 36.768  1   24.172 ? 176  GLU A OE2 1 
ATOM   1236 N  N   . MET A 1 185 ? -5.498  -19.182 33.723  1   24.031 ? 177  MET A N   1 
ATOM   1237 C  CA  . MET A 1 185 ? -4.491  -19.182 32.678  1   20.658 ? 177  MET A CA  1 
ATOM   1238 C  C   . MET A 1 185 ? -3.246  -19.869 33.218  1   18.956 ? 177  MET A C   1 
ATOM   1239 O  O   . MET A 1 185 ? -3.013  -19.859 34.427  1   20.099 ? 177  MET A O   1 
ATOM   1240 C  CB  . MET A 1 185 ? -4.077  -17.76  32.319  1   20.297 ? 177  MET A CB  1 
ATOM   1241 C  CG  . MET A 1 185 ? -5.266  -16.889 31.896  1   21.951 ? 177  MET A CG  1 
ATOM   1242 S  SD  . MET A 1 185 ? -4.905  -15.128 31.841  1   24.028 ? 177  MET A SD  1 
ATOM   1243 C  CE  . MET A 1 185 ? -4.253  -15.024 30.161  1   20.929 ? 177  MET A CE  1 
ATOM   1244 N  N   . ASP A 1 186 ? -2.451  -20.393 32.302  1   21.359 ? 178  ASP A N   1 
ATOM   1245 C  CA  . ASP A 1 186 ? -1.122  -20.909 32.661  1   19.944 ? 178  ASP A CA  1 
ATOM   1246 C  C   . ASP A 1 186 ? -0.25   -19.736 33.09   1   19.475 ? 178  ASP A C   1 
ATOM   1247 O  O   . ASP A 1 186 ? -0.183  -18.751 32.368  1   20.435 ? 178  ASP A O   1 
ATOM   1248 C  CB  . ASP A 1 186 ? -0.498  -21.651 31.493  1   21.432 ? 178  ASP A CB  1 
ATOM   1249 C  CG  . ASP A 1 186 ? 0.83    -22.317 31.852  1   26.714 ? 178  ASP A CG  1 
ATOM   1250 O  OD1 . ASP A 1 186 ? 1.875   -21.623 31.912  1   22.061 ? 178  ASP A OD1 1 
ATOM   1251 O  OD2 . ASP A 1 186 ? 0.779   -23.495 32.198  1   30.101 ? 178  ASP A OD2 1 
ATOM   1252 N  N   . PRO A 1 187 ? 0.457   -19.773 34.244  1   21.979 ? 179  PRO A N   1 
ATOM   1253 C  CA  . PRO A 1 187 ? 1.23    -18.616 34.694  1   22.152 ? 179  PRO A CA  1 
ATOM   1254 C  C   . PRO A 1 187 ? 2.524   -18.321 33.937  1   21.757 ? 179  PRO A C   1 
ATOM   1255 O  O   . PRO A 1 187 ? 3.118   -17.255 34.144  1   23.923 ? 179  PRO A O   1 
ATOM   1256 C  CB  . PRO A 1 187 ? 1.543   -18.904 36.166  1   22.133 ? 179  PRO A CB  1 
ATOM   1257 C  CG  . PRO A 1 187 ? 1.538   -20.392 36.23   1   23.779 ? 179  PRO A CG  1 
ATOM   1258 C  CD  . PRO A 1 187 ? 0.494   -20.869 35.221  1   23.235 ? 179  PRO A CD  1 
ATOM   1259 N  N   . HIS A 1 188 ? 2.914   -19.224 33.042  1   20.311 ? 180  HIS A N   1 
ATOM   1260 C  CA  . HIS A 1 188 ? 4.154   -19.073 32.288  1   21.483 ? 180  HIS A CA  1 
ATOM   1261 C  C   . HIS A 1 188 ? 3.84    -18.732 30.831  1   21.507 ? 180  HIS A C   1 
ATOM   1262 O  O   . HIS A 1 188 ? 4.524   -17.894 30.27   1   23.202 ? 180  HIS A O   1 
ATOM   1263 C  CB  . HIS A 1 188 ? 4.974   -20.373 32.361  1   20.977 ? 180  HIS A CB  1 
ATOM   1264 C  CG  . HIS A 1 188 ? 5.069   -20.894 33.747  1   21.409 ? 180  HIS A CG  1 
ATOM   1265 N  ND1 . HIS A 1 188 ? 5.712   -20.224 34.765  1   21.312 ? 180  HIS A ND1 1 
ATOM   1266 C  CD2 . HIS A 1 188 ? 4.512   -21.972 34.309  1   23.525 ? 180  HIS A CD2 1 
ATOM   1267 C  CE1 . HIS A 1 188 ? 5.602   -20.913 35.903  1   22.53  ? 180  HIS A CE1 1 
ATOM   1268 N  NE2 . HIS A 1 188 ? 4.863   -21.984 35.658  1   24.955 ? 180  HIS A NE2 1 
ATOM   1269 N  N   . THR A 1 189 ? 2.888   -19.452 30.218  1   20.806 ? 181  THR A N   1 
ATOM   1270 C  CA  . THR A 1 189 ? 2.563   -19.267 28.817  1   20.635 ? 181  THR A CA  1 
ATOM   1271 C  C   . THR A 1 189 ? 1.392   -18.31  28.669  1   19.409 ? 181  THR A C   1 
ATOM   1272 O  O   . THR A 1 189 ? 1.119   -17.869 27.549  1   19.626 ? 181  THR A O   1 
ATOM   1273 C  CB  . THR A 1 189 ? 2.247   -20.572 28.084  1   23.724 ? 181  THR A CB  1 
ATOM   1274 O  OG1 . THR A 1 189 ? 1.028   -21.028 28.657  1   23.489 ? 181  THR A OG1 1 
ATOM   1275 C  CG2 . THR A 1 189 ? 3.4     -21.571 28.154  1   25.36  ? 181  THR A CG2 1 
ATOM   1276 N  N   . LEU A 1 190 ? 0.653   -18.107 29.762  1   18.571 ? 182  LEU A N   1 
ATOM   1277 C  CA  . LEU A 1 190 ? -0.619  -17.359 29.751  1   19.554 ? 182  LEU A CA  1 
ATOM   1278 C  C   . LEU A 1 190 ? -1.675  -17.981 28.843  1   19.186 ? 182  LEU A C   1 
ATOM   1279 O  O   . LEU A 1 190 ? -2.667  -17.32  28.554  1   20.757 ? 182  LEU A O   1 
ATOM   1280 C  CB  . LEU A 1 190 ? -0.421  -15.855 29.48   1   18.77  ? 182  LEU A CB  1 
ATOM   1281 C  CG  . LEU A 1 190 ? 0.469   -15.098 30.477  1   20.055 ? 182  LEU A CG  1 
ATOM   1282 C  CD1 . LEU A 1 190 ? 0.694   -13.653 29.995  1   19.608 ? 182  LEU A CD1 1 
ATOM   1283 C  CD2 . LEU A 1 190 ? -0.152  -15.107 31.881  1   20.93  ? 182  LEU A CD2 1 
ATOM   1284 N  N   . LYS A 1 191 ? -1.515  -19.261 28.474  1   20.38  ? 183  LYS A N   1 
ATOM   1285 C  CA  . LYS A 1 191 ? -2.585  -19.991 27.786  1   20.932 ? 183  LYS A CA  1 
ATOM   1286 C  C   . LYS A 1 191 ? -3.794  -20.101 28.699  1   20.099 ? 183  LYS A C   1 
ATOM   1287 O  O   . LYS A 1 191 ? -3.627  -20.311 29.909  1   21.978 ? 183  LYS A O   1 
ATOM   1288 C  CB  . LYS A 1 191 ? -2.03   -21.383 27.41   1   22.232 ? 183  LYS A CB  1 
ATOM   1289 C  CG  . LYS A 1 191 ? -3.024  -22.287 26.688  1   29.925 ? 183  LYS A CG  1 
ATOM   1290 C  CD  . LYS A 1 191 ? -2.411  -23.535 26.059  1   38.266 ? 183  LYS A CD  1 
ATOM   1291 C  CE  . LYS A 1 191 ? -3.413  -24.373 25.285  1   37.349 ? 183  LYS A CE  1 
ATOM   1292 N  NZ  . LYS A 1 191 ? -3.786  -23.594 24.111  1   40.714 ? 183  LYS A NZ  1 
ATOM   1293 N  N   . THR A 1 192 ? -4.999  -19.878 28.128  1   19.094 ? 184  THR A N   1 
ATOM   1294 C  CA  . THR A 1 192 ? -6.219  -20.034 28.913  1   20.069 ? 184  THR A CA  1 
ATOM   1295 C  C   . THR A 1 192 ? -6.514  -21.529 29.106  1   20.965 ? 184  THR A C   1 
ATOM   1296 O  O   . THR A 1 192 ? -6.445  -22.308 28.14   1   19.757 ? 184  THR A O   1 
ATOM   1297 C  CB  . THR A 1 192 ? -7.362  -19.305 28.217  1   21.194 ? 184  THR A CB  1 
ATOM   1298 O  OG1 . THR A 1 192 ? -6.967  -17.928 28.26   1   22.81  ? 184  THR A OG1 1 
ATOM   1299 C  CG2 . THR A 1 192 ? -8.67   -19.483 28.979  1   19.108 ? 184  THR A CG2 1 
ATOM   1300 N  N   . LEU A 1 193 ? -6.839  -21.89  30.362  1   21.571 ? 185  LEU A N   1 
ATOM   1301 C  CA  . LEU A 1 193 ? -6.998  -23.279 30.77   1   22.721 ? 185  LEU A CA  1 
ATOM   1302 C  C   . LEU A 1 193 ? -8.454  -23.652 31.049  1   21.688 ? 185  LEU A C   1 
ATOM   1303 O  O   . LEU A 1 193 ? -8.791  -24.831 30.967  1   21.92  ? 185  LEU A O   1 
ATOM   1304 C  CB  . LEU A 1 193 ? -6.144  -23.628 31.975  1   22.416 ? 185  LEU A CB  1 
ATOM   1305 C  CG  . LEU A 1 193 ? -4.647  -23.344 31.824  1   23.06  ? 185  LEU A CG  1 
ATOM   1306 C  CD1 . LEU A 1 193 ? -3.96   -23.688 33.131  1   23.738 ? 185  LEU A CD1 1 
ATOM   1307 C  CD2 . LEU A 1 193 ? -4.038  -24.127 30.624  1   24.423 ? 185  LEU A CD2 1 
ATOM   1308 N  N   . GLY A 1 194 ? -9.309  -22.68  31.373  1   19.473 ? 186  GLY A N   1 
ATOM   1309 C  CA  . GLY A 1 194 ? -10.678 -23.032 31.724  1   21.022 ? 186  GLY A CA  1 
ATOM   1310 C  C   . GLY A 1 194 ? -11.402 -21.873 32.392  1   23.95  ? 186  GLY A C   1 
ATOM   1311 O  O   . GLY A 1 194 ? -10.819 -20.8   32.57   1   23.041 ? 186  GLY A O   1 
ATOM   1312 N  N   . TYR A 1 195 ? -12.673 -22.138 32.737  1   21.779 ? 187  TYR A N   1 
ATOM   1313 C  CA  . TYR A 1 195 ? -13.529 -21.165 33.396  1   20.063 ? 187  TYR A CA  1 
ATOM   1314 C  C   . TYR A 1 195 ? -13.995 -21.736 34.726  1   20.553 ? 187  TYR A C   1 
ATOM   1315 O  O   . TYR A 1 195 ? -14.27  -22.933 34.827  1   20.93  ? 187  TYR A O   1 
ATOM   1316 C  CB  . TYR A 1 195 ? -14.722 -20.948 32.457  1   20.176 ? 187  TYR A CB  1 
ATOM   1317 C  CG  . TYR A 1 195 ? -15.816 -20.079 33.059  1   22.01  ? 187  TYR A CG  1 
ATOM   1318 C  CD1 . TYR A 1 195 ? -15.664 -18.686 33.097  1   21.331 ? 187  TYR A CD1 1 
ATOM   1319 C  CD2 . TYR A 1 195 ? -16.994 -20.638 33.58   1   19.747 ? 187  TYR A CD2 1 
ATOM   1320 C  CE1 . TYR A 1 195 ? -16.632 -17.85  33.626  1   20.682 ? 187  TYR A CE1 1 
ATOM   1321 C  CE2 . TYR A 1 195 ? -17.979 -19.797 34.105  1   19.992 ? 187  TYR A CE2 1 
ATOM   1322 C  CZ  . TYR A 1 195 ? -17.806 -18.412 34.112  1   21.571 ? 187  TYR A CZ  1 
ATOM   1323 O  OH  . TYR A 1 195 ? -18.754 -17.6   34.653  1   21.132 ? 187  TYR A OH  1 
ATOM   1324 N  N   . ASN A 1 196 ? -14.113 -20.859 35.722  1   18.381 ? 188  ASN A N   1 
ATOM   1325 C  CA  . ASN A 1 196 ? -14.685 -21.181 37.028  1   19.967 ? 188  ASN A CA  1 
ATOM   1326 C  C   . ASN A 1 196 ? -13.949 -22.354 37.666  1   21.894 ? 188  ASN A C   1 
ATOM   1327 O  O   . ASN A 1 196 ? -14.564 -23.389 38.012  1   21.512 ? 188  ASN A O   1 
ATOM   1328 C  CB  . ASN A 1 196 ? -16.186 -21.458 36.938  1   17.728 ? 188  ASN A CB  1 
ATOM   1329 C  CG  . ASN A 1 196 ? -16.879 -21.439 38.29   1   22.309 ? 188  ASN A CG  1 
ATOM   1330 O  OD1 . ASN A 1 196 ? -16.294 -21.044 39.309  1   21.409 ? 188  ASN A OD1 1 
ATOM   1331 N  ND2 . ASN A 1 196 ? -18.159 -21.794 38.294  1   23.469 ? 188  ASN A ND2 1 
ATOM   1332 N  N   . PRO A 1 197 ? -12.609 -22.247 37.838  1   21.456 ? 189  PRO A N   1 
ATOM   1333 C  CA  . PRO A 1 197 ? -11.826 -23.38  38.337  1   22.578 ? 189  PRO A CA  1 
ATOM   1334 C  C   . PRO A 1 197 ? -12.234 -23.908 39.715  1   22.57  ? 189  PRO A C   1 
ATOM   1335 O  O   . PRO A 1 197 ? -12.086 -25.104 39.974  1   24.004 ? 189  PRO A O   1 
ATOM   1336 C  CB  . PRO A 1 197 ? -10.41  -22.825 38.317  1   23.443 ? 189  PRO A CB  1 
ATOM   1337 C  CG  . PRO A 1 197 ? -10.596 -21.339 38.474  1   24.341 ? 189  PRO A CG  1 
ATOM   1338 C  CD  . PRO A 1 197 ? -11.758 -21.077 37.565  1   21.432 ? 189  PRO A CD  1 
ATOM   1339 N  N   . PHE A 1 198 ? -12.74  -23.038 40.589  1   21.599 ? 190  PHE A N   1 
ATOM   1340 C  CA  . PHE A 1 198 ? -13.214 -23.437 41.917  1   22.9   ? 190  PHE A CA  1 
ATOM   1341 C  C   . PHE A 1 198 ? -14.695 -23.851 41.939  1   23.271 ? 190  PHE A C   1 
ATOM   1342 O  O   . PHE A 1 198 ? -15.261 -24.124 43.027  1   23.327 ? 190  PHE A O   1 
ATOM   1343 C  CB  . PHE A 1 198 ? -12.966 -22.295 42.907  1   25.552 ? 190  PHE A CB  1 
ATOM   1344 C  CG  . PHE A 1 198 ? -11.504 -21.885 43.008  1   25.316 ? 190  PHE A CG  1 
ATOM   1345 C  CD1 . PHE A 1 198 ? -10.481 -22.841 43.085  1   22.802 ? 190  PHE A CD1 1 
ATOM   1346 C  CD2 . PHE A 1 198 ? -11.153 -20.549 42.917  1   26.277 ? 190  PHE A CD2 1 
ATOM   1347 C  CE1 . PHE A 1 198 ? -9.14   -22.468 43.177  1   27.376 ? 190  PHE A CE1 1 
ATOM   1348 C  CE2 . PHE A 1 198 ? -9.808  -20.166 43.011  1   27.529 ? 190  PHE A CE2 1 
ATOM   1349 C  CZ  . PHE A 1 198 ? -8.799  -21.125 43.115  1   27.681 ? 190  PHE A CZ  1 
ATOM   1350 N  N   . ASN A 1 199 ? -15.332 -23.879 40.763  1   22.445 ? 191  ASN A N   1 
ATOM   1351 C  CA  . ASN A 1 199 ? -16.708 -24.344 40.599  1   22.547 ? 191  ASN A CA  1 
ATOM   1352 C  C   . ASN A 1 199 ? -17.66  -23.601 41.537  1   24.493 ? 191  ASN A C   1 
ATOM   1353 O  O   . ASN A 1 199 ? -18.444 -24.208 42.27   1   24.486 ? 191  ASN A O   1 
ATOM   1354 C  CB  . ASN A 1 199 ? -16.846 -25.863 40.835  1   25.417 ? 191  ASN A CB  1 
ATOM   1355 C  CG  . ASN A 1 199 ? -16.215 -26.643 39.717  1   32.547 ? 191  ASN A CG  1 
ATOM   1356 O  OD1 . ASN A 1 199 ? -15.25  -27.392 39.95   1   38.528 ? 191  ASN A OD1 1 
ATOM   1357 N  ND2 . ASN A 1 199 ? -16.723 -26.462 38.509  1   31.963 ? 191  ASN A ND2 1 
ATOM   1358 N  N   . LEU A 1 200 ? -17.526 -22.278 41.607  1   23.211 ? 192  LEU A N   1 
ATOM   1359 C  CA  . LEU A 1 200 ? -18.479 -21.501 42.379  1   21.692 ? 192  LEU A CA  1 
ATOM   1360 C  C   . LEU A 1 200 ? -19.888 -21.674 41.818  1   21.834 ? 192  LEU A C   1 
ATOM   1361 O  O   . LEU A 1 200 ? -20.072 -21.727 40.603  1   22.905 ? 192  LEU A O   1 
ATOM   1362 C  CB  . LEU A 1 200 ? -18.08  -20.028 42.516  1   22.681 ? 192  LEU A CB  1 
ATOM   1363 C  CG  . LEU A 1 200 ? -16.639 -19.784 43.001  1   21.422 ? 192  LEU A CG  1 
ATOM   1364 C  CD1 . LEU A 1 200 ? -16.523 -18.263 43.157  1   21.633 ? 192  LEU A CD1 1 
ATOM   1365 C  CD2 . LEU A 1 200 ? -16.314 -20.465 44.307  1   24.241 ? 192  LEU A CD2 1 
ATOM   1366 N  N   . PRO A 1 201 ? -20.919 -21.75  42.706  1   22.969 ? 193  PRO A N   1 
ATOM   1367 C  CA  . PRO A 1 201 ? -22.309 -21.892 42.273  1   23.977 ? 193  PRO A CA  1 
ATOM   1368 C  C   . PRO A 1 201 ? -22.934 -20.591 41.773  1   24.318 ? 193  PRO A C   1 
ATOM   1369 O  O   . PRO A 1 201 ? -23.96  -20.605 41.1    1   25.622 ? 193  PRO A O   1 
ATOM   1370 C  CB  . PRO A 1 201 ? -23.066 -22.361 43.533  1   23.893 ? 193  PRO A CB  1 
ATOM   1371 C  CG  . PRO A 1 201 ? -22.2   -21.779 44.656  1   23.102 ? 193  PRO A CG  1 
ATOM   1372 C  CD  . PRO A 1 201 ? -20.766 -21.858 44.169  1   22.726 ? 193  PRO A CD  1 
ATOM   1373 N  N   . SER A 1 202 ? -22.328 -19.451 42.131  1   21.591 ? 194  SER A N   1 
ATOM   1374 C  CA  . SER A 1 202 ? -22.828 -18.179 41.622  1   22.922 ? 194  SER A CA  1 
ATOM   1375 C  C   . SER A 1 202 ? -22.421 -18.034 40.149  1   21.97  ? 194  SER A C   1 
ATOM   1376 O  O   . SER A 1 202 ? -21.486 -18.698 39.667  1   21.866 ? 194  SER A O   1 
ATOM   1377 C  CB  . SER A 1 202 ? -22.252 -17.059 42.421  1   26.077 ? 194  SER A CB  1 
ATOM   1378 O  OG  . SER A 1 202 ? -20.855 -17.222 42.48   1   32.463 ? 194  SER A OG  1 
ATOM   1379 N  N   . LYS A 1 203 ? -23.108 -17.141 39.436  1   19.217 ? 195  LYS A N   1 
ATOM   1380 C  CA  . LYS A 1 203 ? -22.732 -16.868 38.059  1   17.648 ? 195  LYS A CA  1 
ATOM   1381 C  C   . LYS A 1 203 ? -21.539 -15.9   38.019  1   17.738 ? 195  LYS A C   1 
ATOM   1382 O  O   . LYS A 1 203 ? -20.972 -15.689 36.93   1   19.28  ? 195  LYS A O   1 
ATOM   1383 C  CB  . LYS A 1 203 ? -23.914 -16.269 37.306  1   20.475 ? 195  LYS A CB  1 
ATOM   1384 C  CG  . LYS A 1 203 ? -25.104 -17.253 37.191  1   20.483 ? 195  LYS A CG  1 
ATOM   1385 C  CD  . LYS A 1 203 ? -26.18  -16.563 36.369  1   26.48  ? 195  LYS A CD  1 
ATOM   1386 C  CE  . LYS A 1 203 ? -27.285 -17.545 36.557  1   27.493 ? 195  LYS A CE  1 
ATOM   1387 N  NZ  . LYS A 1 203 ? -27.815 -17.94  35.287  1   30.973 ? 195  LYS A NZ  1 
ATOM   1388 N  N   . THR A 1 204 ? -21.197 -15.298 39.171  1   18.36  ? 196  THR A N   1 
ATOM   1389 C  CA  . THR A 1 204 ? -20.219 -14.192 39.16   1   20.319 ? 196  THR A CA  1 
ATOM   1390 C  C   . THR A 1 204 ? -19.218 -14.415 40.275  1   21.595 ? 196  THR A C   1 
ATOM   1391 O  O   . THR A 1 204 ? -19.544 -15.106 41.278  1   21.077 ? 196  THR A O   1 
ATOM   1392 C  CB  . THR A 1 204 ? -20.91  -12.832 39.375  1   20.807 ? 196  THR A CB  1 
ATOM   1393 O  OG1 . THR A 1 204 ? -21.593 -12.937 40.643  1   21.819 ? 196  THR A OG1 1 
ATOM   1394 C  CG2 . THR A 1 204 ? -21.921 -12.525 38.277  1   21.566 ? 196  THR A CG2 1 
ATOM   1395 N  N   . MET A 1 205 ? -18.045 -13.77  40.098  1   18.935 ? 197  MET A N   1 
ATOM   1396 C  CA  . MET A 1 205 ? -17.13  -13.668 41.222  1   19.35  ? 197  MET A CA  1 
ATOM   1397 C  C   . MET A 1 205 ? -16.527 -12.273 41.162  1   19.787 ? 197  MET A C   1 
ATOM   1398 O  O   . MET A 1 205 ? -16.153 -11.812 40.1    1   19.206 ? 197  MET A O   1 
ATOM   1399 C  CB  . MET A 1 205 ? -15.993 -14.713 41.164  1   18.097 ? 197  MET A CB  1 
ATOM   1400 C  CG  . MET A 1 205 ? -15.137 -14.68  42.45   1   17.167 ? 197  MET A CG  1 
ATOM   1401 S  SD  . MET A 1 205 ? -13.665 -15.721 42.324  1   20.782 ? 197  MET A SD  1 
ATOM   1402 C  CE  . MET A 1 205 ? -12.602 -14.666 41.332  1   21.293 ? 197  MET A CE  1 
ATOM   1403 N  N   . THR A 1 206 ? -16.396 -11.633 42.329  1   20.801 ? 198  THR A N   1 
ATOM   1404 C  CA  . THR A 1 206 ? -15.697 -10.353 42.408  1   20.106 ? 198  THR A CA  1 
ATOM   1405 C  C   . THR A 1 206 ? -14.308 -10.465 41.758  1   21.028 ? 198  THR A C   1 
ATOM   1406 O  O   . THR A 1 206 ? -13.641 -11.535 41.801  1   17.614 ? 198  THR A O   1 
ATOM   1407 C  CB  . THR A 1 206 ? -15.611 -9.958  43.889  1   18.404 ? 198  THR A CB  1 
ATOM   1408 O  OG1 . THR A 1 206 ? -15.061 -8.639  43.908  1   20.598 ? 198  THR A OG1 1 
ATOM   1409 C  CG2 . THR A 1 206 ? -14.667 -10.83  44.701  1   20.326 ? 198  THR A CG2 1 
ATOM   1410 N  N   . ALA A 1 207 ? -13.838 -9.327  41.23   1   18.316 ? 199  ALA A N   1 
ATOM   1411 C  CA  . ALA A 1 207 ? -12.444 -9.223  40.794  1   19.912 ? 199  ALA A CA  1 
ATOM   1412 C  C   . ALA A 1 207 ? -11.579 -8.738  41.945  1   19.466 ? 199  ALA A C   1 
ATOM   1413 O  O   . ALA A 1 207 ? -10.394 -8.532  41.725  1   20.424 ? 199  ALA A O   1 
ATOM   1414 C  CB  . ALA A 1 207 ? -12.317 -8.287  39.604  1   23.261 ? 199  ALA A CB  1 
ATOM   1415 N  N   . HIS A 1 208 ? -12.176 -8.592  43.15   1   17.382 ? 200  HIS A N   1 
ATOM   1416 C  CA  . HIS A 1 208 ? -11.439 -8.172  44.333  1   19.032 ? 200  HIS A CA  1 
ATOM   1417 C  C   . HIS A 1 208 ? -11.537 -9.182  45.469  1   20.407 ? 200  HIS A C   1 
ATOM   1418 O  O   . HIS A 1 208 ? -11.8   -8.787  46.601  1   21.074 ? 200  HIS A O   1 
ATOM   1419 C  CB  . HIS A 1 208 ? -11.866 -6.749  44.744  1   19.141 ? 200  HIS A CB  1 
ATOM   1420 C  CG  . HIS A 1 208 ? -11.268 -5.713  43.844  1   20.358 ? 200  HIS A CG  1 
ATOM   1421 N  ND1 . HIS A 1 208 ? -9.914  -5.461  43.878  1   19.298 ? 200  HIS A ND1 1 
ATOM   1422 C  CD2 . HIS A 1 208 ? -11.794 -4.953  42.852  1   18.306 ? 200  HIS A CD2 1 
ATOM   1423 C  CE1 . HIS A 1 208 ? -9.625  -4.528  42.975  1   21.209 ? 200  HIS A CE1 1 
ATOM   1424 N  NE2 . HIS A 1 208 ? -10.767 -4.18   42.35   1   19.979 ? 200  HIS A NE2 1 
ATOM   1425 N  N   . PRO A 1 209 ? -11.239 -10.494 45.262  1   19.186 ? 201  PRO A N   1 
ATOM   1426 C  CA  . PRO A 1 209 ? -11.146 -11.385 46.4    1   17.495 ? 201  PRO A CA  1 
ATOM   1427 C  C   . PRO A 1 209 ? -9.877  -11.117 47.17   1   22.808 ? 201  PRO A C   1 
ATOM   1428 O  O   . PRO A 1 209 ? -8.924  -10.56  46.625  1   22.463 ? 201  PRO A O   1 
ATOM   1429 C  CB  . PRO A 1 209 ? -11.121 -12.783 45.773  1   21.905 ? 201  PRO A CB  1 
ATOM   1430 C  CG  . PRO A 1 209 ? -10.383 -12.508 44.444  1   19.736 ? 201  PRO A CG  1 
ATOM   1431 C  CD  . PRO A 1 209 ? -10.893 -11.141 43.988  1   17.655 ? 201  PRO A CD  1 
ATOM   1432 N  N   . LYS A 1 210 ? -9.893  -11.457 48.457  1   20.591 ? 202  LYS A N   1 
ATOM   1433 C  CA  . LYS A 1 210 ? -8.778  -11.094 49.323  1   19.608 ? 202  LYS A CA  1 
ATOM   1434 C  C   . LYS A 1 210 ? -8.182  -12.383 49.881  1   22.489 ? 202  LYS A C   1 
ATOM   1435 O  O   . LYS A 1 210 ? -8.929  -13.263 50.342  1   22.821 ? 202  LYS A O   1 
ATOM   1436 C  CB  . LYS A 1 210 ? -9.342  -10.265 50.477  1   19.705 ? 202  LYS A CB  1 
ATOM   1437 C  CG  . LYS A 1 210 ? -10.136 -8.987  50.1    1   18.332 ? 202  LYS A CG  1 
ATOM   1438 C  CD  . LYS A 1 210 ? -9.401  -7.943  49.259  1   19.756 ? 202  LYS A CD  1 
ATOM   1439 C  CE  . LYS A 1 210 ? -10.377 -6.887  48.77   1   21.146 ? 202  LYS A CE  1 
ATOM   1440 N  NZ  . LYS A 1 210 ? -9.706  -5.846  47.938  1   22.196 ? 202  LYS A NZ  1 
ATOM   1441 N  N   . GLN A 1 211 ? -6.85   -12.478 49.808  1   22.3   ? 203  GLN A N   1 
ATOM   1442 C  CA  . GLN A 1 211 ? -6.167  -13.686 50.221  1   23.931 ? 203  GLN A CA  1 
ATOM   1443 C  C   . GLN A 1 211 ? -5.724  -13.488 51.66   1   23.333 ? 203  GLN A C   1 
ATOM   1444 O  O   . GLN A 1 211 ? -4.767  -12.776 51.91   1   23.464 ? 203  GLN A O   1 
ATOM   1445 C  CB  . GLN A 1 211 ? -5.039  -13.989 49.239  1   23.837 ? 203  GLN A CB  1 
ATOM   1446 C  CG  . GLN A 1 211 ? -4.466  -15.392 49.359  1   36.132 ? 203  GLN A CG  1 
ATOM   1447 C  CD  . GLN A 1 211 ? -3.559  -15.73  48.187  1   41.741 ? 203  GLN A CD  1 
ATOM   1448 O  OE1 . GLN A 1 211 ? -3.91   -16.499 47.276  1   36.637 ? 203  GLN A OE1 1 
ATOM   1449 N  NE2 . GLN A 1 211 ? -2.397  -15.099 48.175  1   39.893 ? 203  GLN A NE2 1 
ATOM   1450 N  N   . CYS A 1 212 ? -6.454  -14.137 52.556  1   23.573 ? 204  CYS A N   1 
ATOM   1451 C  CA  . CYS A 1 212 ? -6.326  -14.027 53.994  1   22.919 ? 204  CYS A CA  1 
ATOM   1452 C  C   . CYS A 1 212 ? -4.922  -14.472 54.424  1   20.941 ? 204  CYS A C   1 
ATOM   1453 O  O   . CYS A 1 212 ? -4.485  -15.576 54.116  1   23.071 ? 204  CYS A O   1 
ATOM   1454 C  CB  . CYS A 1 212 ? -7.378  -14.918 54.639  1   22.579 ? 204  CYS A CB  1 
ATOM   1455 S  SG  . CYS A 1 212 ? -7.326  -14.878 56.453  1   25.641 ? 204  CYS A SG  1 
ATOM   1456 N  N   . SER A 1 213 ? -4.227  -13.606 55.151  1   22.627 ? 205  SER A N   1 
ATOM   1457 C  CA  . SER A 1 213 ? -2.852  -13.932 55.549  1   26.487 ? 205  SER A CA  1 
ATOM   1458 C  C   . SER A 1 213 ? -2.846  -14.858 56.769  1   30.171 ? 205  SER A C   1 
ATOM   1459 O  O   . SER A 1 213 ? -1.794  -15.396 57.104  1   32.31  ? 205  SER A O   1 
ATOM   1460 C  CB  . SER A 1 213 ? -2.052  -12.681 55.769  1   31.579 ? 205  SER A CB  1 
ATOM   1461 O  OG  . SER A 1 213 ? -2.557  -12.013 56.923  1   37.441 ? 205  SER A OG  1 
ATOM   1462 N  N   . VAL A 1 214 ? -4.014  -15.079 57.387  1   28.336 ? 206  VAL A N   1 
ATOM   1463 C  CA  . VAL A 1 214 ? -4.128  -15.971 58.543  1   31.075 ? 206  VAL A CA  1 
ATOM   1464 C  C   . VAL A 1 214 ? -4.446  -17.387 58.079  1   31.582 ? 206  VAL A C   1 
ATOM   1465 O  O   . VAL A 1 214 ? -3.711  -18.306 58.422  1   31.727 ? 206  VAL A O   1 
ATOM   1466 C  CB  . VAL A 1 214 ? -5.119  -15.49  59.616  1   31.464 ? 206  VAL A CB  1 
ATOM   1467 C  CG1 . VAL A 1 214 ? -5.258  -16.483 60.778  1   33.516 ? 206  VAL A CG1 1 
ATOM   1468 C  CG2 . VAL A 1 214 ? -4.695  -14.139 60.148  1   27.597 ? 206  VAL A CG2 1 
ATOM   1469 N  N   . THR A 1 215 ? -5.532  -17.549 57.296  1   23.54  ? 207  THR A N   1 
ATOM   1470 C  CA  . THR A 1 215 ? -6.014  -18.863 56.904  1   25.578 ? 207  THR A CA  1 
ATOM   1471 C  C   . THR A 1 215 ? -5.443  -19.247 55.531  1   26.846 ? 207  THR A C   1 
ATOM   1472 O  O   . THR A 1 215 ? -5.462  -20.418 55.149  1   27.242 ? 207  THR A O   1 
ATOM   1473 C  CB  . THR A 1 215 ? -7.545  -18.877 56.897  1   28.207 ? 207  THR A CB  1 
ATOM   1474 O  OG1 . THR A 1 215 ? -7.913  -17.977 55.845  1   25.733 ? 207  THR A OG1 1 
ATOM   1475 C  CG2 . THR A 1 215 ? -8.178  -18.448 58.218  1   27.147 ? 207  THR A CG2 1 
ATOM   1476 N  N   . GLY A 1 216 ? -5.022  -18.246 54.739  1   24.774 ? 208  GLY A N   1 
ATOM   1477 C  CA  . GLY A 1 216 ? -4.641  -18.525 53.357  1   24.425 ? 208  GLY A CA  1 
ATOM   1478 C  C   . GLY A 1 216 ? -5.85   -18.616 52.435  1   23.999 ? 208  GLY A C   1 
ATOM   1479 O  O   . GLY A 1 216 ? -5.692  -18.837 51.219  1   24.423 ? 208  GLY A O   1 
ATOM   1480 N  N   . ASN A 1 217 ? -7.047  -18.453 53      1   20.537 ? 209  ASN A N   1 
ATOM   1481 C  CA  . ASN A 1 217 ? -8.275  -18.555 52.223  1   20.416 ? 209  ASN A CA  1 
ATOM   1482 C  C   . ASN A 1 217 ? -8.399  -17.382 51.244  1   20.383 ? 209  ASN A C   1 
ATOM   1483 O  O   . ASN A 1 217 ? -8.024  -16.259 51.562  1   21.81  ? 209  ASN A O   1 
ATOM   1484 C  CB  . ASN A 1 217 ? -9.538  -18.53  53.092  1   24.242 ? 209  ASN A CB  1 
ATOM   1485 C  CG  . ASN A 1 217 ? -9.706  -19.764 53.963  1   24.952 ? 209  ASN A CG  1 
ATOM   1486 O  OD1 . ASN A 1 217 ? -8.999  -20.765 53.799  1   24.661 ? 209  ASN A OD1 1 
ATOM   1487 N  ND2 . ASN A 1 217 ? -10.685 -19.744 54.848  1   24.383 ? 209  ASN A ND2 1 
ATOM   1488 N  N   . LEU A 1 218 ? -8.921  -17.69  50.037  1   22.098 ? 210  LEU A N   1 
ATOM   1489 C  CA  . LEU A 1 218 ? -9.355  -16.637 49.134  1   21.123 ? 210  LEU A CA  1 
ATOM   1490 C  C   . LEU A 1 218 ? -10.796 -16.299 49.524  1   20.069 ? 210  LEU A C   1 
ATOM   1491 O  O   . LEU A 1 218 ? -11.699 -17.113 49.32   1   22.194 ? 210  LEU A O   1 
ATOM   1492 C  CB  . LEU A 1 218 ? -9.285  -17.131 47.68   1   20.769 ? 210  LEU A CB  1 
ATOM   1493 C  CG  . LEU A 1 218 ? -9.505  -16.063 46.607  1   23.288 ? 210  LEU A CG  1 
ATOM   1494 C  CD1 . LEU A 1 218 ? -8.418  -14.945 46.619  1   21.636 ? 210  LEU A CD1 1 
ATOM   1495 C  CD2 . LEU A 1 218 ? -9.686  -16.78  45.237  1   26.363 ? 210  LEU A CD2 1 
ATOM   1496 N  N   . VAL A 1 219 ? -10.98  -15.08  50.042  1   20.791 ? 211  VAL A N   1 
ATOM   1497 C  CA  . VAL A 1 219 ? -12.26  -14.678 50.588  1   21.236 ? 211  VAL A CA  1 
ATOM   1498 C  C   . VAL A 1 219 ? -12.884 -13.685 49.625  1   21.005 ? 211  VAL A C   1 
ATOM   1499 O  O   . VAL A 1 219 ? -12.245 -12.701 49.242  1   21.543 ? 211  VAL A O   1 
ATOM   1500 C  CB  . VAL A 1 219 ? -12.097 -14.047 51.982  1   20.758 ? 211  VAL A CB  1 
ATOM   1501 C  CG1 . VAL A 1 219 ? -13.463 -13.715 52.606  1   21.57  ? 211  VAL A CG1 1 
ATOM   1502 C  CG2 . VAL A 1 219 ? -11.274 -14.936 52.911  1   20.985 ? 211  VAL A CG2 1 
ATOM   1503 N  N   . GLY A 1 220 ? -14.132 -13.957 49.244  1   20.726 ? 212  GLY A N   1 
ATOM   1504 C  CA  . GLY A 1 220 ? -14.729 -13.046 48.28   1   21.72  ? 212  GLY A CA  1 
ATOM   1505 C  C   . GLY A 1 220 ? -16.228 -13.248 48.214  1   19.225 ? 212  GLY A C   1 
ATOM   1506 O  O   . GLY A 1 220 ? -16.855 -13.764 49.139  1   20.373 ? 212  GLY A O   1 
ATOM   1507 N  N   . PHE A 1 221 ? -16.792 -12.795 47.096  1   21.21  ? 213  PHE A N   1 
ATOM   1508 C  CA  . PHE A 1 221 ? -18.24  -12.749 46.932  1   16.711 ? 213  PHE A CA  1 
ATOM   1509 C  C   . PHE A 1 221 ? -18.517 -12.636 45.441  1   20.455 ? 213  PHE A C   1 
ATOM   1510 O  O   . PHE A 1 221 ? -17.601 -12.331 44.667  1   21.266 ? 213  PHE A O   1 
ATOM   1511 C  CB  . PHE A 1 221 ? -18.882 -11.575 47.704  1   19.892 ? 213  PHE A CB  1 
ATOM   1512 C  CG  . PHE A 1 221 ? -18.495 -10.218 47.138  1   20.571 ? 213  PHE A CG  1 
ATOM   1513 C  CD1 . PHE A 1 221 ? -17.242 -9.661  47.437  1   20.391 ? 213  PHE A CD1 1 
ATOM   1514 C  CD2 . PHE A 1 221 ? -19.386 -9.518  46.303  1   21.436 ? 213  PHE A CD2 1 
ATOM   1515 C  CE1 . PHE A 1 221 ? -16.866 -8.445  46.881  1   22.298 ? 213  PHE A CE1 1 
ATOM   1516 C  CE2 . PHE A 1 221 ? -18.981 -8.32   45.725  1   22.156 ? 213  PHE A CE2 1 
ATOM   1517 C  CZ  . PHE A 1 221 ? -17.737 -7.781  46.015  1   18.979 ? 213  PHE A CZ  1 
ATOM   1518 N  N   . GLY A 1 222 ? -19.791 -12.797 45.066  1   20.131 ? 214  GLY A N   1 
ATOM   1519 C  CA  . GLY A 1 222 ? -20.183 -12.439 43.704  1   20.641 ? 214  GLY A CA  1 
ATOM   1520 C  C   . GLY A 1 222 ? -21.56  -11.788 43.835  1   22.158 ? 214  GLY A C   1 
ATOM   1521 O  O   . GLY A 1 222 ? -22.4   -12.311 44.591  1   23.169 ? 214  GLY A O   1 
ATOM   1522 N  N   . TYR A 1 223 ? -21.798 -10.666 43.135  1   19.38  ? 215  TYR A N   1 
ATOM   1523 C  CA  . TYR A 1 223 ? -23.121 -10.037 43.201  1   19.33  ? 215  TYR A CA  1 
ATOM   1524 C  C   . TYR A 1 223 ? -23.775 -10.224 41.845  1   18.755 ? 215  TYR A C   1 
ATOM   1525 O  O   . TYR A 1 223 ? -23.127 -10.722 40.938  1   21.81  ? 215  TYR A O   1 
ATOM   1526 C  CB  . TYR A 1 223 ? -23.022 -8.581  43.717  1   19.948 ? 215  TYR A CB  1 
ATOM   1527 C  CG  . TYR A 1 223 ? -22.417 -7.653  42.68   1   18.936 ? 215  TYR A CG  1 
ATOM   1528 C  CD1 . TYR A 1 223 ? -21.027 -7.501  42.543  1   18.403 ? 215  TYR A CD1 1 
ATOM   1529 C  CD2 . TYR A 1 223 ? -23.26  -6.913  41.835  1   22.253 ? 215  TYR A CD2 1 
ATOM   1530 C  CE1 . TYR A 1 223 ? -20.481 -6.658  41.569  1   19.243 ? 215  TYR A CE1 1 
ATOM   1531 C  CE2 . TYR A 1 223 ? -22.736 -6.067  40.864  1   19.902 ? 215  TYR A CE2 1 
ATOM   1532 C  CZ  . TYR A 1 223 ? -21.355 -5.921  40.751  1   20.412 ? 215  TYR A CZ  1 
ATOM   1533 O  OH  . TYR A 1 223 ? -20.844 -5.097  39.799  1   21.203 ? 215  TYR A OH  1 
ATOM   1534 N  N   . GLU A 1 224 ? -25.078 -9.907  41.737  1   19.218 ? 216  GLU A N   1 
ATOM   1535 C  CA  . GLU A 1 224 ? -25.915 -10.397 40.639  1   18.728 ? 216  GLU A CA  1 
ATOM   1536 C  C   . GLU A 1 224 ? -25.688 -11.894 40.465  1   20.296 ? 216  GLU A C   1 
ATOM   1537 O  O   . GLU A 1 224 ? -25.531 -12.39  39.339  1   19.531 ? 216  GLU A O   1 
ATOM   1538 C  CB  . GLU A 1 224 ? -25.699 -9.646  39.31   1   17.901 ? 216  GLU A CB  1 
ATOM   1539 C  CG  . GLU A 1 224 ? -25.958 -8.148  39.522  1   19.095 ? 216  GLU A CG  1 
ATOM   1540 C  CD  . GLU A 1 224 ? -26.092 -7.322  38.262  1   21.994 ? 216  GLU A CD  1 
ATOM   1541 O  OE1 . GLU A 1 224 ? -26.46  -7.859  37.195  1   21.502 ? 216  GLU A OE1 1 
ATOM   1542 O  OE2 . GLU A 1 224 ? -25.902 -6.083  38.355  1   22.32  ? 216  GLU A OE2 1 
ATOM   1543 N  N   . ALA A 1 225 ? -25.615 -12.586 41.624  1   19.534 ? 217  ALA A N   1 
ATOM   1544 C  CA  . ALA A 1 225 ? -25.145 -13.961 41.648  1   20.565 ? 217  ALA A CA  1 
ATOM   1545 C  C   . ALA A 1 225 ? -26.08  -14.924 40.907  1   22.164 ? 217  ALA A C   1 
ATOM   1546 O  O   . ALA A 1 225 ? -25.627 -16.001 40.513  1   22.119 ? 217  ALA A O   1 
ATOM   1547 C  CB  . ALA A 1 225 ? -24.924 -14.38  43.089  1   19.734 ? 217  ALA A CB  1 
ATOM   1548 N  N   . LYS A 1 226 ? -27.35  -14.506 40.688  1   22.801 ? 218  LYS A N   1 
ATOM   1549 C  CA  . LYS A 1 226 ? -28.303 -15.379 40.014  1   25.578 ? 218  LYS A CA  1 
ATOM   1550 C  C   . LYS A 1 226 ? -28.656 -14.844 38.633  1   24.958 ? 218  LYS A C   1 
ATOM   1551 O  O   . LYS A 1 226 ? -29.574 -15.375 38.015  1   27.709 ? 218  LYS A O   1 
ATOM   1552 C  CB  . LYS A 1 226 ? -29.581 -15.615 40.833  1   23.502 ? 218  LYS A CB  1 
ATOM   1553 C  CG  . LYS A 1 226 ? -29.253 -16.389 42.113  1   25.253 ? 218  LYS A CG  1 
ATOM   1554 C  CD  . LYS A 1 226 ? -30.549 -16.861 42.768  1   31.646 ? 218  LYS A CD  1 
ATOM   1555 C  CE  . LYS A 1 226 ? -30.387 -17.518 44.092  1   35.527 ? 218  LYS A CE  1 
ATOM   1556 N  NZ  . LYS A 1 226 ? -31.614 -18.308 44.348  1   35.585 ? 218  LYS A NZ  1 
ATOM   1557 N  N   . GLY A 1 227 ? -27.91  -13.861 38.134  1   22.191 ? 219  GLY A N   1 
ATOM   1558 C  CA  . GLY A 1 227 ? -28.223 -13.38  36.79   1   22.779 ? 219  GLY A CA  1 
ATOM   1559 C  C   . GLY A 1 227 ? -28.434 -11.874 36.747  1   20.46  ? 219  GLY A C   1 
ATOM   1560 O  O   . GLY A 1 227 ? -28.392 -11.187 37.772  1   23.931 ? 219  GLY A O   1 
ATOM   1561 N  N   . LEU A 1 228 ? -28.697 -11.354 35.527  1   21.007 ? 220  LEU A N   1 
ATOM   1562 C  CA  . LEU A 1 228 ? -28.845 -9.93   35.297  1   21.754 ? 220  LEU A CA  1 
ATOM   1563 C  C   . LEU A 1 228 ? -29.845 -9.29   36.259  1   23.955 ? 220  LEU A C   1 
ATOM   1564 O  O   . LEU A 1 228 ? -31.012 -9.688  36.313  1   23.548 ? 220  LEU A O   1 
ATOM   1565 C  CB  . LEU A 1 228 ? -29.346 -9.866  33.855  1   23.838 ? 220  LEU A CB  1 
ATOM   1566 C  CG  . LEU A 1 228 ? -28.751 -8.827  32.911  1   31.432 ? 220  LEU A CG  1 
ATOM   1567 C  CD1 . LEU A 1 228 ? -27.206 -8.725  32.814  1   22.895 ? 220  LEU A CD1 1 
ATOM   1568 C  CD2 . LEU A 1 228 ? -29.327 -9.244  31.549  1   26.594 ? 220  LEU A CD2 1 
ATOM   1569 N  N   . ALA A 1 229 ? -29.349 -8.241  36.936  1   21.565 ? 221  ALA A N   1 
ATOM   1570 C  CA  . ALA A 1 229 ? -30.083 -7.36   37.826  1   22.391 ? 221  ALA A CA  1 
ATOM   1571 C  C   . ALA A 1 229 ? -30.587 -8.074  39.082  1   22.715 ? 221  ALA A C   1 
ATOM   1572 O  O   . ALA A 1 229 ? -31.419 -7.504  39.771  1   24.713 ? 221  ALA A O   1 
ATOM   1573 C  CB  . ALA A 1 229 ? -31.209 -6.597  37.066  1   22.757 ? 221  ALA A CB  1 
ATOM   1574 N  N   . THR A 1 230 ? -30.077 -9.274  39.42   1   20.86  ? 222  THR A N   1 
ATOM   1575 C  CA  . THR A 1 230 ? -30.543 -9.955  40.623  1   20.196 ? 222  THR A CA  1 
ATOM   1576 C  C   . THR A 1 230 ? -29.882 -9.292  41.829  1   21.113 ? 222  THR A C   1 
ATOM   1577 O  O   . THR A 1 230 ? -28.717 -8.862  41.786  1   22.187 ? 222  THR A O   1 
ATOM   1578 C  CB  . THR A 1 230 ? -30.333 -11.478 40.576  1   22.846 ? 222  THR A CB  1 
ATOM   1579 O  OG1 . THR A 1 230 ? -28.927 -11.722 40.403  1   22.143 ? 222  THR A OG1 1 
ATOM   1580 C  CG2 . THR A 1 230 ? -31.169 -12.136 39.477  1   21.915 ? 222  THR A CG2 1 
ATOM   1581 N  N   . LYS A 1 231 ? -30.596 -9.276  42.953  1   20.791 ? 223  LYS A N   1 
ATOM   1582 C  CA  . LYS A 1 231 ? -30.041 -8.726  44.198  1   22.07  ? 223  LYS A CA  1 
ATOM   1583 C  C   . LYS A 1 231 ? -29.21  -9.734  44.974  1   22.707 ? 223  LYS A C   1 
ATOM   1584 O  O   . LYS A 1 231 ? -28.563 -9.38   45.97   1   21.242 ? 223  LYS A O   1 
ATOM   1585 C  CB  . LYS A 1 231 ? -31.184 -8.221  45.096  1   22.09  ? 223  LYS A CB  1 
ATOM   1586 C  CG  . LYS A 1 231 ? -31.759 -6.938  44.504  1   23.979 ? 223  LYS A CG  1 
ATOM   1587 C  CD  . LYS A 1 231 ? -32.761 -6.244  45.44   1   29.848 ? 223  LYS A CD  1 
ATOM   1588 C  CE  . LYS A 1 231 ? -33.9   -7.13   45.838  1   33.749 ? 223  LYS A CE  1 
ATOM   1589 N  NZ  . LYS A 1 231 ? -34.867 -6.406  46.675  1   42.245 ? 223  LYS A NZ  1 
ATOM   1590 N  N   . ASP A 1 232 ? -29.204 -11.003 44.517  1   21.215 ? 224  ASP A N   1 
ATOM   1591 C  CA  . ASP A 1 232 ? -28.461 -12.048 45.21   1   21.829 ? 224  ASP A CA  1 
ATOM   1592 C  C   . ASP A 1 232 ? -26.957 -11.776 45.267  1   22.326 ? 224  ASP A C   1 
ATOM   1593 O  O   . ASP A 1 232 ? -26.324 -11.392 44.285  1   22.158 ? 224  ASP A O   1 
ATOM   1594 C  CB  . ASP A 1 232 ? -28.698 -13.384 44.539  1   23.297 ? 224  ASP A CB  1 
ATOM   1595 C  CG  . ASP A 1 232 ? -30.183 -13.683 44.462  1   26.947 ? 224  ASP A CG  1 
ATOM   1596 O  OD1 . ASP A 1 232 ? -30.685 -14.23  45.432  1   25.164 ? 224  ASP A OD1 1 
ATOM   1597 O  OD2 . ASP A 1 232 ? -30.807 -13.258 43.487  1   28.555 ? 224  ASP A OD2 1 
ATOM   1598 N  N   . VAL A 1 233 ? -26.399 -12.014 46.453  1   21.754 ? 225  VAL A N   1 
ATOM   1599 C  CA  . VAL A 1 233 ? -24.968 -11.98  46.7    1   22.332 ? 225  VAL A CA  1 
ATOM   1600 C  C   . VAL A 1 233 ? -24.551 -13.315 47.304  1   23.684 ? 225  VAL A C   1 
ATOM   1601 O  O   . VAL A 1 233 ? -25.216 -13.803 48.228  1   21.59  ? 225  VAL A O   1 
ATOM   1602 C  CB  . VAL A 1 233 ? -24.627 -10.798 47.623  1   20.885 ? 225  VAL A CB  1 
ATOM   1603 C  CG1 . VAL A 1 233 ? -23.148 -10.795 48.042  1   22.345 ? 225  VAL A CG1 1 
ATOM   1604 C  CG2 . VAL A 1 233 ? -25.015 -9.476  46.949  1   19.454 ? 225  VAL A CG2 1 
ATOM   1605 N  N   . TYR A 1 234 ? -23.449 -13.864 46.772  1   21.506 ? 226  TYR A N   1 
ATOM   1606 C  CA  . TYR A 1 234 ? -22.886 -15.108 47.288  1   21.663 ? 226  TYR A CA  1 
ATOM   1607 C  C   . TYR A 1 234 ? -21.542 -14.789 47.919  1   23.636 ? 226  TYR A C   1 
ATOM   1608 O  O   . TYR A 1 234 ? -20.646 -14.311 47.225  1   22.607 ? 226  TYR A O   1 
ATOM   1609 C  CB  . TYR A 1 234 ? -22.736 -16.089 46.117  1   22.355 ? 226  TYR A CB  1 
ATOM   1610 C  CG  . TYR A 1 234 ? -21.992 -17.371 46.47   1   23.444 ? 226  TYR A CG  1 
ATOM   1611 C  CD1 . TYR A 1 234 ? -22.591 -18.316 47.3    1   23.971 ? 226  TYR A CD1 1 
ATOM   1612 C  CD2 . TYR A 1 234 ? -20.751 -17.667 45.894  1   21.587 ? 226  TYR A CD2 1 
ATOM   1613 C  CE1 . TYR A 1 234 ? -21.956 -19.515 47.581  1   24.638 ? 226  TYR A CE1 1 
ATOM   1614 C  CE2 . TYR A 1 234 ? -20.116 -18.876 46.148  1   23.182 ? 226  TYR A CE2 1 
ATOM   1615 C  CZ  . TYR A 1 234 ? -20.711 -19.769 47.036  1   24.854 ? 226  TYR A CZ  1 
ATOM   1616 O  OH  . TYR A 1 234 ? -20.114 -20.96  47.3    1   23.713 ? 226  TYR A OH  1 
ATOM   1617 N  N   . TYR A 1 235 ? -21.387 -15.087 49.219  1   20.084 ? 227  TYR A N   1 
ATOM   1618 C  CA  . TYR A 1 235 ? -20.094 -14.99  49.888  1   20.222 ? 227  TYR A CA  1 
ATOM   1619 C  C   . TYR A 1 235 ? -19.389 -16.352 49.876  1   20.429 ? 227  TYR A C   1 
ATOM   1620 O  O   . TYR A 1 235 ? -20.031 -17.379 50.053  1   21.395 ? 227  TYR A O   1 
ATOM   1621 C  CB  . TYR A 1 235 ? -20.391 -14.54  51.334  1   21.85  ? 227  TYR A CB  1 
ATOM   1622 C  CG  . TYR A 1 235 ? -19.41  -15.048 52.395  1   24.734 ? 227  TYR A CG  1 
ATOM   1623 C  CD1 . TYR A 1 235 ? -18.13  -14.499 52.547  1   24.795 ? 227  TYR A CD1 1 
ATOM   1624 C  CD2 . TYR A 1 235 ? -19.785 -16.095 53.243  1   25.822 ? 227  TYR A CD2 1 
ATOM   1625 C  CE1 . TYR A 1 235 ? -17.266 -14.96  53.533  1   25.107 ? 227  TYR A CE1 1 
ATOM   1626 C  CE2 . TYR A 1 235 ? -18.906 -16.606 54.192  1   25.138 ? 227  TYR A CE2 1 
ATOM   1627 C  CZ  . TYR A 1 235 ? -17.655 -16.02  54.341  1   23.297 ? 227  TYR A CZ  1 
ATOM   1628 O  OH  . TYR A 1 235 ? -16.786 -16.446 55.295  1   23.614 ? 227  TYR A OH  1 
ATOM   1629 N  N   . PHE A 1 236 ? -18.06  -16.366 49.796  1   21.604 ? 228  PHE A N   1 
ATOM   1630 C  CA  . PHE A 1 236 ? -17.345 -17.64  49.879  1   20.265 ? 228  PHE A CA  1 
ATOM   1631 C  C   . PHE A 1 236 ? -15.965 -17.427 50.492  1   20.597 ? 228  PHE A C   1 
ATOM   1632 O  O   . PHE A 1 236 ? -15.422 -16.321 50.473  1   22.83  ? 228  PHE A O   1 
ATOM   1633 C  CB  . PHE A 1 236 ? -17.254 -18.262 48.471  1   20.353 ? 228  PHE A CB  1 
ATOM   1634 C  CG  . PHE A 1 236 ? -16.446 -17.387 47.508  1   21.421 ? 228  PHE A CG  1 
ATOM   1635 C  CD1 . PHE A 1 236 ? -15.052 -17.453 47.515  1   21.741 ? 228  PHE A CD1 1 
ATOM   1636 C  CD2 . PHE A 1 236 ? -17.078 -16.47  46.661  1   23.028 ? 228  PHE A CD2 1 
ATOM   1637 C  CE1 . PHE A 1 236 ? -14.291 -16.626 46.688  1   21.944 ? 228  PHE A CE1 1 
ATOM   1638 C  CE2 . PHE A 1 236 ? -16.306 -15.673 45.793  1   20.618 ? 228  PHE A CE2 1 
ATOM   1639 C  CZ  . PHE A 1 236 ? -14.928 -15.742 45.824  1   22.003 ? 228  PHE A CZ  1 
ATOM   1640 N  N   . GLU A 1 237 ? -15.373 -18.556 50.953  1   18.511 ? 229  GLU A N   1 
ATOM   1641 C  CA  . GLU A 1 237 ? -13.953 -18.671 51.216  1   20.657 ? 229  GLU A CA  1 
ATOM   1642 C  C   . GLU A 1 237 ? -13.498 -19.974 50.555  1   22.721 ? 229  GLU A C   1 
ATOM   1643 O  O   . GLU A 1 237 ? -14.085 -21.03  50.802  1   21.76  ? 229  GLU A O   1 
ATOM   1644 C  CB  . GLU A 1 237 ? -13.64  -18.648 52.725  1   20.404 ? 229  GLU A CB  1 
ATOM   1645 C  CG  . GLU A 1 237 ? -14.203 -17.389 53.386  1   21.455 ? 229  GLU A CG  1 
ATOM   1646 C  CD  . GLU A 1 237 ? -13.609 -17.029 54.739  1   23.844 ? 229  GLU A CD  1 
ATOM   1647 O  OE1 . GLU A 1 237 ? -12.541 -17.577 55.062  1   23.489 ? 229  GLU A OE1 1 
ATOM   1648 O  OE2 . GLU A 1 237 ? -14.183 -16.183 55.444  1   27.122 ? 229  GLU A OE2 1 
ATOM   1649 N  N   . VAL A 1 238 ? -12.519 -19.85  49.648  1   22.998 ? 230  VAL A N   1 
ATOM   1650 C  CA  . VAL A 1 238 ? -11.874 -20.972 48.994  1   24.674 ? 230  VAL A CA  1 
ATOM   1651 C  C   . VAL A 1 238 ? -10.567 -21.204 49.74   1   23.419 ? 230  VAL A C   1 
ATOM   1652 O  O   . VAL A 1 238 ? -9.707  -20.308 49.827  1   23.73  ? 230  VAL A O   1 
ATOM   1653 C  CB  . VAL A 1 238 ? -11.659 -20.7   47.487  1   24.261 ? 230  VAL A CB  1 
ATOM   1654 C  CG1 . VAL A 1 238 ? -10.869 -21.809 46.798  1   22.08  ? 230  VAL A CG1 1 
ATOM   1655 C  CG2 . VAL A 1 238 ? -12.98  -20.518 46.769  1   27.624 ? 230  VAL A CG2 1 
ATOM   1656 N  N   . ASP A 1 239 ? -10.416 -22.429 50.253  1   24.045 ? 231  ASP A N   1 
ATOM   1657 C  CA  . ASP A 1 239 ? -9.237  -22.718 51.074  1   23.311 ? 231  ASP A CA  1 
ATOM   1658 C  C   . ASP A 1 239 ? -7.986  -22.854 50.197  1   25.081 ? 231  ASP A C   1 
ATOM   1659 O  O   . ASP A 1 239 ? -8.121  -22.877 48.958  1   24.773 ? 231  ASP A O   1 
ATOM   1660 C  CB  . ASP A 1 239 ? -9.514  -23.897 51.999  1   26.409 ? 231  ASP A CB  1 
ATOM   1661 C  CG  . ASP A 1 239 ? -9.445  -25.293 51.389  1   29.038 ? 231  ASP A CG  1 
ATOM   1662 O  OD1 . ASP A 1 239 ? -9.182  -25.447 50.17   1   27.931 ? 231  ASP A OD1 1 
ATOM   1663 O  OD2 . ASP A 1 239 ? -9.752  -26.213 52.149  1   32.942 ? 231  ASP A OD2 1 
ATOM   1664 N  N   . PRO A 1 240 ? -6.752  -22.966 50.788  1   25.102 ? 232  PRO A N   1 
ATOM   1665 C  CA  . PRO A 1 240 ? -5.518  -23.143 50.02   1   28.842 ? 232  PRO A CA  1 
ATOM   1666 C  C   . PRO A 1 240 ? -5.475  -24.339 49.075  1   30.8   ? 232  PRO A C   1 
ATOM   1667 O  O   . PRO A 1 240 ? -4.625  -24.387 48.185  1   27.425 ? 232  PRO A O   1 
ATOM   1668 C  CB  . PRO A 1 240 ? -4.438  -23.215 51.095  1   31.334 ? 232  PRO A CB  1 
ATOM   1669 C  CG  . PRO A 1 240 ? -5.019  -22.346 52.196  1   29.176 ? 232  PRO A CG  1 
ATOM   1670 C  CD  . PRO A 1 240 ? -6.443  -22.8   52.233  1   26.207 ? 232  PRO A CD  1 
ATOM   1671 N  N   . SER A 1 241 ? -6.437  -25.262 49.236  1   28.607 ? 233  SER A N   1 
ATOM   1672 C  CA  . SER A 1 241 ? -6.46   -26.461 48.43   1   28.923 ? 233  SER A CA  1 
ATOM   1673 C  C   . SER A 1 241 ? -7.411  -26.291 47.256  1   31.516 ? 233  SER A C   1 
ATOM   1674 O  O   . SER A 1 241 ? -7.48   -27.189 46.42   1   31.53  ? 233  SER A O   1 
ATOM   1675 C  CB  . SER A 1 241 ? -6.75   -27.688 49.292  1   34.964 ? 233  SER A CB  1 
ATOM   1676 O  OG  . SER A 1 241 ? -8.162  -27.822 49.468  1   36.322 ? 233  SER A OG  1 
ATOM   1677 N  N   . GLY A 1 242 ? -8.107  -25.138 47.176  1   26.273 ? 234  GLY A N   1 
ATOM   1678 C  CA  . GLY A 1 242 ? -8.956  -24.838 46.038  1   25.329 ? 234  GLY A CA  1 
ATOM   1679 C  C   . GLY A 1 242 ? -10.391 -25.332 46.209  1   31.057 ? 234  GLY A C   1 
ATOM   1680 O  O   . GLY A 1 242 ? -11.076 -25.538 45.2    1   35.007 ? 234  GLY A O   1 
ATOM   1681 N  N   . LYS A 1 243 ? -10.843 -25.463 47.463  1   30.609 ? 235  LYS A N   1 
ATOM   1682 C  CA  . LYS A 1 243 ? -12.187 -25.941 47.778  1   34.724 ? 235  LYS A CA  1 
ATOM   1683 C  C   . LYS A 1 243 ? -12.964 -24.849 48.529  1   28.383 ? 235  LYS A C   1 
ATOM   1684 O  O   . LYS A 1 243 ? -12.403 -24.226 49.418  1   24.531 ? 235  LYS A O   1 
ATOM   1685 C  CB  . LYS A 1 243 ? -11.896 -27.101 48.739  1   43.189 ? 235  LYS A CB  1 
ATOM   1686 C  CG  . LYS A 1 243 ? -12.986 -27.868 49.425  1   52.752 ? 235  LYS A CG  1 
ATOM   1687 C  CD  . LYS A 1 243 ? -12.378 -28.588 50.625  1   55.587 ? 235  LYS A CD  1 
ATOM   1688 C  CE  . LYS A 1 243 ? -13.474 -28.814 51.636  1   55.844 ? 235  LYS A CE  1 
ATOM   1689 N  NZ  . LYS A 1 243 ? -13.125 -29.15  53.032  1   42.092 ? 235  LYS A NZ  1 
ATOM   1690 N  N   . VAL A 1 244 ? -14.262 -24.69  48.232  1   27.843 ? 236  VAL A N   1 
ATOM   1691 C  CA  . VAL A 1 244 ? -15.109 -23.776 49.003  1   29.324 ? 236  VAL A CA  1 
ATOM   1692 C  C   . VAL A 1 244 ? -15.337 -24.418 50.379  1   27.794 ? 236  VAL A C   1 
ATOM   1693 O  O   . VAL A 1 244 ? -15.933 -25.492 50.473  1   36.084 ? 236  VAL A O   1 
ATOM   1694 C  CB  . VAL A 1 244 ? -16.446 -23.532 48.274  1   28.656 ? 236  VAL A CB  1 
ATOM   1695 C  CG1 . VAL A 1 244 ? -17.455 -22.713 49.082  1   27.297 ? 236  VAL A CG1 1 
ATOM   1696 C  CG2 . VAL A 1 244 ? -16.224 -22.866 46.919  1   29.725 ? 236  VAL A CG2 1 
ATOM   1697 N  N   . VAL A 1 245 ? -14.896 -23.738 51.428  1   25.063 ? 237  VAL A N   1 
ATOM   1698 C  CA  . VAL A 1 245 ? -14.973 -24.238 52.796  1   26.122 ? 237  VAL A CA  1 
ATOM   1699 C  C   . VAL A 1 245 ? -16.027 -23.482 53.598  1   29.48  ? 237  VAL A C   1 
ATOM   1700 O  O   . VAL A 1 245 ? -16.464 -23.963 54.643  1   26.796 ? 237  VAL A O   1 
ATOM   1701 C  CB  . VAL A 1 245 ? -13.633 -24.277 53.553  1   30.237 ? 237  VAL A CB  1 
ATOM   1702 C  CG1 . VAL A 1 245 ? -12.763 -25.383 52.988  1   31.459 ? 237  VAL A CG1 1 
ATOM   1703 C  CG2 . VAL A 1 245 ? -12.923 -22.916 53.585  1   28.077 ? 237  VAL A CG2 1 
ATOM   1704 N  N   . ARG A 1 246 ? -16.4   -22.281 53.133  1   28.435 ? 238  ARG A N   1 
ATOM   1705 C  CA  . ARG A 1 246 ? -17.414 -21.462 53.787  1   27.499 ? 238  ARG A CA  1 
ATOM   1706 C  C   . ARG A 1 246 ? -18.164 -20.744 52.678  1   27.877 ? 238  ARG A C   1 
ATOM   1707 O  O   . ARG A 1 246 ? -17.53  -20.321 51.715  1   26.883 ? 238  ARG A O   1 
ATOM   1708 C  CB  . ARG A 1 246 ? -16.803 -20.335 54.62   1   27.805 ? 238  ARG A CB  1 
ATOM   1709 C  CG  . ARG A 1 246 ? -16.182 -20.848 55.91   1   27.992 ? 238  ARG A CG  1 
ATOM   1710 C  CD  . ARG A 1 246 ? -15.354 -19.715 56.431  1   28.985 ? 238  ARG A CD  1 
ATOM   1711 N  NE  . ARG A 1 246 ? -14.971 -20.031 57.813  1   33.977 ? 238  ARG A NE  1 
ATOM   1712 C  CZ  . ARG A 1 246 ? -14.196 -19.227 58.585  1   36.064 ? 238  ARG A CZ  1 
ATOM   1713 N  NH1 . ARG A 1 246 ? -13.673 -18.118 58.103  1   32.385 ? 238  ARG A NH1 1 
ATOM   1714 N  NH2 . ARG A 1 246 ? -13.938 -19.558 59.844  1   37.543 ? 238  ARG A NH2 1 
ATOM   1715 N  N   . ASP A 1 247 ? -19.493 -20.641 52.808  1   23.2   ? 239  ASP A N   1 
ATOM   1716 C  CA  . ASP A 1 247 ? -20.203 -19.771 51.879  1   22.703 ? 239  ASP A CA  1 
ATOM   1717 C  C   . ASP A 1 247 ? -21.528 -19.336 52.495  1   25.991 ? 239  ASP A C   1 
ATOM   1718 O  O   . ASP A 1 247 ? -21.876 -19.771 53.587  1   23.441 ? 239  ASP A O   1 
ATOM   1719 C  CB  . ASP A 1 247 ? -20.354 -20.429 50.519  1   22.228 ? 239  ASP A CB  1 
ATOM   1720 C  CG  . ASP A 1 247 ? -21.324 -21.59  50.369  1   27.275 ? 239  ASP A CG  1 
ATOM   1721 O  OD1 . ASP A 1 247 ? -22.154 -21.851 51.29   1   24.93  ? 239  ASP A OD1 1 
ATOM   1722 O  OD2 . ASP A 1 247 ? -21.321 -22.176 49.263  1   29.031 ? 239  ASP A OD2 1 
ATOM   1723 N  N   . LEU A 1 248 ? -22.266 -18.493 51.771  1   22.893 ? 240  LEU A N   1 
ATOM   1724 C  CA  . LEU A 1 248 ? -23.526 -17.951 52.285  1   23.63  ? 240  LEU A CA  1 
ATOM   1725 C  C   . LEU A 1 248 ? -24.211 -17.24  51.134  1   23.675 ? 240  LEU A C   1 
ATOM   1726 O  O   . LEU A 1 248 ? -23.544 -16.467 50.446  1   24.637 ? 240  LEU A O   1 
ATOM   1727 C  CB  . LEU A 1 248 ? -23.367 -16.953 53.439  1   23.245 ? 240  LEU A CB  1 
ATOM   1728 C  CG  . LEU A 1 248 ? -24.677 -16.488 54.107  1   27.456 ? 240  LEU A CG  1 
ATOM   1729 C  CD1 . LEU A 1 248 ? -25.457 -17.634 54.823  1   28.993 ? 240  LEU A CD1 1 
ATOM   1730 C  CD2 . LEU A 1 248 ? -24.372 -15.325 55.048  1   24.805 ? 240  LEU A CD2 1 
ATOM   1731 N  N   . TRP A 1 249 ? -25.508 -17.476 50.982  1   20.538 ? 241  TRP A N   1 
ATOM   1732 C  CA  . TRP A 1 249 ? -26.322 -16.689 50.06   1   21.749 ? 241  TRP A CA  1 
ATOM   1733 C  C   . TRP A 1 249 ? -27.051 -15.61  50.843  1   23.297 ? 241  TRP A C   1 
ATOM   1734 O  O   . TRP A 1 249 ? -27.595 -15.862 51.921  1   23.556 ? 241  TRP A O   1 
ATOM   1735 C  CB  . TRP A 1 249 ? -27.303 -17.608 49.317  1   23.429 ? 241  TRP A CB  1 
ATOM   1736 C  CG  . TRP A 1 249 ? -26.582 -18.521 48.377  1   23.1   ? 241  TRP A CG  1 
ATOM   1737 C  CD1 . TRP A 1 249 ? -25.976 -19.717 48.636  1   23.082 ? 241  TRP A CD1 1 
ATOM   1738 C  CD2 . TRP A 1 249 ? -26.402 -18.251 46.97   1   23.579 ? 241  TRP A CD2 1 
ATOM   1739 N  NE1 . TRP A 1 249 ? -25.434 -20.226 47.482  1   24.594 ? 241  TRP A NE1 1 
ATOM   1740 C  CE2 . TRP A 1 249 ? -25.703 -19.361 46.44   1   23.146 ? 241  TRP A CE2 1 
ATOM   1741 C  CE3 . TRP A 1 249 ? -26.799 -17.192 46.119  1   24.685 ? 241  TRP A CE3 1 
ATOM   1742 C  CZ2 . TRP A 1 249 ? -25.353 -19.433 45.086  1   22.881 ? 241  TRP A CZ2 1 
ATOM   1743 C  CZ3 . TRP A 1 249 ? -26.458 -17.264 44.778  1   25.902 ? 241  TRP A CZ3 1 
ATOM   1744 C  CH2 . TRP A 1 249 ? -25.729 -18.363 44.287  1   26.57  ? 241  TRP A CH2 1 
ATOM   1745 N  N   . LEU A 1 250 ? -27.037 -14.388 50.298  1   22.769 ? 242  LEU A N   1 
ATOM   1746 C  CA  . LEU A 1 250 ? -27.652 -13.231 50.931  1   22.363 ? 242  LEU A CA  1 
ATOM   1747 C  C   . LEU A 1 250 ? -28.12  -12.299 49.815  1   23.524 ? 242  LEU A C   1 
ATOM   1748 O  O   . LEU A 1 250 ? -28.162 -12.685 48.655  1   23.885 ? 242  LEU A O   1 
ATOM   1749 C  CB  . LEU A 1 250 ? -26.672 -12.554 51.902  1   21.542 ? 242  LEU A CB  1 
ATOM   1750 C  CG  . LEU A 1 250 ? -25.364 -12.045 51.256  1   23.664 ? 242  LEU A CG  1 
ATOM   1751 C  CD1 . LEU A 1 250 ? -25.11  -10.586 51.688  1   20.068 ? 242  LEU A CD1 1 
ATOM   1752 C  CD2 . LEU A 1 250 ? -24.151 -12.949 51.582  1   21.677 ? 242  LEU A CD2 1 
ATOM   1753 N  N   . GLU A 1 251 ? -28.547 -11.082 50.188  1   26.036 ? 243  GLU A N   1 
ATOM   1754 C  CA  . GLU A 1 251 ? -28.956 -10.101 49.194  1   26.884 ? 243  GLU A CA  1 
ATOM   1755 C  C   . GLU A 1 251 ? -28.379 -8.747  49.559  1   26.856 ? 243  GLU A C   1 
ATOM   1756 O  O   . GLU A 1 251 ? -28.097 -8.495  50.72   1   25.656 ? 243  GLU A O   1 
ATOM   1757 C  CB  . GLU A 1 251 ? -30.474 -9.967  49.16   1   31.292 ? 243  GLU A CB  1 
ATOM   1758 C  CG  . GLU A 1 251 ? -31.158 -11.156 48.494  1   36.962 ? 243  GLU A CG  1 
ATOM   1759 C  CD  . GLU A 1 251 ? -32.66  -10.972 48.558  1   45.164 ? 243  GLU A CD  1 
ATOM   1760 O  OE1 . GLU A 1 251 ? -33.213 -10.969 49.672  1   50.482 ? 243  GLU A OE1 1 
ATOM   1761 O  OE2 . GLU A 1 251 ? -33.266 -10.876 47.478  1   51.705 ? 243  GLU A OE2 1 
ATOM   1762 N  N   . ALA A 1 252 ? -28.218 -7.902  48.531  1   24.922 ? 244  ALA A N   1 
ATOM   1763 C  CA  . ALA A 1 252 ? -27.957 -6.501  48.745  1   23.266 ? 244  ALA A CA  1 
ATOM   1764 C  C   . ALA A 1 252 ? -29.299 -5.758  48.845  1   24.189 ? 244  ALA A C   1 
ATOM   1765 O  O   . ALA A 1 252 ? -30.341 -6.222  48.323  1   21.718 ? 244  ALA A O   1 
ATOM   1766 C  CB  . ALA A 1 252 ? -27.054 -5.963  47.604  1   21.016 ? 244  ALA A CB  1 
ATOM   1767 N  N   . PRO A 1 253 ? -29.318 -4.573  49.52   1   24.721 ? 245  PRO A N   1 
ATOM   1768 C  CA  . PRO A 1 253 ? -30.55  -3.795  49.669  1   24.968 ? 245  PRO A CA  1 
ATOM   1769 C  C   . PRO A 1 253 ? -31.156 -3.339  48.342  1   26.212 ? 245  PRO A C   1 
ATOM   1770 O  O   . PRO A 1 253 ? -32.375 -3.138  48.247  1   25.751 ? 245  PRO A O   1 
ATOM   1771 C  CB  . PRO A 1 253 ? -30.162 -2.658  50.593  1   25.03  ? 245  PRO A CB  1 
ATOM   1772 C  CG  . PRO A 1 253 ? -28.621 -2.581  50.517  1   24.934 ? 245  PRO A CG  1 
ATOM   1773 C  CD  . PRO A 1 253 ? -28.188 -4.011  50.308  1   24.099 ? 245  PRO A CD  1 
ATOM   1774 N  N   . TRP A 1 254 ? -30.291 -3.137  47.33   1   21.617 ? 246  TRP A N   1 
ATOM   1775 C  CA  . TRP A 1 254 ? -30.757 -2.91   45.964  1   20.765 ? 246  TRP A CA  1 
ATOM   1776 C  C   . TRP A 1 254 ? -29.729 -3.584  45.065  1   20.62  ? 246  TRP A C   1 
ATOM   1777 O  O   . TRP A 1 254 ? -28.688 -4.011  45.567  1   22.287 ? 246  TRP A O   1 
ATOM   1778 C  CB  . TRP A 1 254 ? -30.92  -1.402  45.62   1   22.479 ? 246  TRP A CB  1 
ATOM   1779 C  CG  . TRP A 1 254 ? -29.626 -0.627  45.435  1   23.498 ? 246  TRP A CG  1 
ATOM   1780 C  CD1 . TRP A 1 254 ? -28.983 -0.344  44.248  1   22.919 ? 246  TRP A CD1 1 
ATOM   1781 C  CD2 . TRP A 1 254 ? -28.844 0.002   46.475  1   22.711 ? 246  TRP A CD2 1 
ATOM   1782 N  NE1 . TRP A 1 254 ? -27.845 0.385   44.486  1   24.685 ? 246  TRP A NE1 1 
ATOM   1783 C  CE2 . TRP A 1 254 ? -27.726 0.602   45.843  1   23.635 ? 246  TRP A CE2 1 
ATOM   1784 C  CE3 . TRP A 1 254 ? -28.982 0.109   47.877  1   25.746 ? 246  TRP A CE3 1 
ATOM   1785 C  CZ2 . TRP A 1 254 ? -26.756 1.316   46.555  1   23.817 ? 246  TRP A CZ2 1 
ATOM   1786 C  CZ3 . TRP A 1 254 ? -28.001 0.79    48.584  1   27.891 ? 246  TRP A CZ3 1 
ATOM   1787 C  CH2 . TRP A 1 254 ? -26.914 1.394   47.927  1   25.085 ? 246  TRP A CH2 1 
ATOM   1788 N  N   . CYS A 1 255 ? -30.008 -3.648  43.757  1   22.082 ? 247  CYS A N   1 
ATOM   1789 C  CA  . CYS A 1 255 ? -29.031 -4.263  42.873  1   22.821 ? 247  CYS A CA  1 
ATOM   1790 C  C   . CYS A 1 255 ? -27.973 -3.194  42.632  1   21.543 ? 247  CYS A C   1 
ATOM   1791 O  O   . CYS A 1 255 ? -28.146 -2.335  41.775  1   21.967 ? 247  CYS A O   1 
ATOM   1792 C  CB  . CYS A 1 255 ? -29.618 -4.857  41.579  1   25.179 ? 247  CYS A CB  1 
ATOM   1793 S  SG  . CYS A 1 255 ? -28.313 -5.69   40.624  1   25.021 ? 247  CYS A SG  1 
ATOM   1794 N  N   . ALA A 1 256 ? -26.902 -3.279  43.438  1   20.793 ? 248  ALA A N   1 
ATOM   1795 C  CA  . ALA A 1 256 ? -25.869 -2.27   43.542  1   19.854 ? 248  ALA A CA  1 
ATOM   1796 C  C   . ALA A 1 256 ? -24.586 -2.752  42.884  1   19.279 ? 248  ALA A C   1 
ATOM   1797 O  O   . ALA A 1 256 ? -24.337 -3.955  42.814  1   19.311 ? 248  ALA A O   1 
ATOM   1798 C  CB  . ALA A 1 256 ? -25.555 -2.012  45.01   1   21.661 ? 248  ALA A CB  1 
ATOM   1799 N  N   . PHE A 1 257 ? -23.761 -1.787  42.478  1   20.861 ? 249  PHE A N   1 
ATOM   1800 C  CA  . PHE A 1 257 ? -22.473 -2.073  41.871  1   21.049 ? 249  PHE A CA  1 
ATOM   1801 C  C   . PHE A 1 257 ? -21.482 -2.275  43.017  1   20.003 ? 249  PHE A C   1 
ATOM   1802 O  O   . PHE A 1 257 ? -20.972 -1.315  43.582  1   19.961 ? 249  PHE A O   1 
ATOM   1803 C  CB  . PHE A 1 257 ? -22.196 -0.839  41.009  1   19.993 ? 249  PHE A CB  1 
ATOM   1804 C  CG  . PHE A 1 257 ? -21.07  -0.935  39.98   1   20.241 ? 249  PHE A CG  1 
ATOM   1805 C  CD1 . PHE A 1 257 ? -19.96  -1.805  40.139  1   19.404 ? 249  PHE A CD1 1 
ATOM   1806 C  CD2 . PHE A 1 257 ? -21.141 -0.146  38.831  1   19.377 ? 249  PHE A CD2 1 
ATOM   1807 C  CE1 . PHE A 1 257 ? -18.956 -1.869  39.15   1   19.082 ? 249  PHE A CE1 1 
ATOM   1808 C  CE2 . PHE A 1 257 ? -20.156 -0.217  37.851  1   19.134 ? 249  PHE A CE2 1 
ATOM   1809 C  CZ  . PHE A 1 257 ? -19.055 -1.07   38.006  1   19     ? 249  PHE A CZ  1 
ATOM   1810 N  N   . ILE A 1 258 ? -21.213 -3.535  43.348  1   17.222 ? 250  ILE A N   1 
ATOM   1811 C  CA  . ILE A 1 258 ? -20.368 -3.901  44.483  1   17.667 ? 250  ILE A CA  1 
ATOM   1812 C  C   . ILE A 1 258 ? -19.004 -4.324  43.936  1   19.095 ? 250  ILE A C   1 
ATOM   1813 O  O   . ILE A 1 258 ? -18.694 -5.504  43.821  1   18.734 ? 250  ILE A O   1 
ATOM   1814 C  CB  . ILE A 1 258 ? -20.995 -4.989  45.38   1   19.103 ? 250  ILE A CB  1 
ATOM   1815 C  CG1 . ILE A 1 258 ? -22.48  -4.747  45.656  1   20.26  ? 250  ILE A CG1 1 
ATOM   1816 C  CG2 . ILE A 1 258 ? -20.161 -5.104  46.671  1   17.495 ? 250  ILE A CG2 1 
ATOM   1817 C  CD1 . ILE A 1 258 ? -23.135 -5.773  46.588  1   22.18  ? 250  ILE A CD1 1 
ATOM   1818 N  N   . HIS A 1 259 ? -18.139 -3.34   43.708  1   18.549 ? 251  HIS A N   1 
ATOM   1819 C  CA  . HIS A 1 259 ? -16.888 -3.6    43.01   1   19.453 ? 251  HIS A CA  1 
ATOM   1820 C  C   . HIS A 1 259 ? -15.843 -4.215  43.94   1   22.151 ? 251  HIS A C   1 
ATOM   1821 O  O   . HIS A 1 259 ? -15.143 -5.144  43.532  1   22.288 ? 251  HIS A O   1 
ATOM   1822 C  CB  . HIS A 1 259 ? -16.317 -2.284  42.454  1   19.773 ? 251  HIS A CB  1 
ATOM   1823 C  CG  . HIS A 1 259 ? -15.046 -2.497  41.695  1   19.887 ? 251  HIS A CG  1 
ATOM   1824 N  ND1 . HIS A 1 259 ? -15.014 -3.228  40.532  1   21.046 ? 251  HIS A ND1 1 
ATOM   1825 C  CD2 . HIS A 1 259 ? -13.771 -2.098  41.922  1   19.509 ? 251  HIS A CD2 1 
ATOM   1826 C  CE1 . HIS A 1 259 ? -13.76  -3.28   40.087  1   20.253 ? 251  HIS A CE1 1 
ATOM   1827 N  NE2 . HIS A 1 259 ? -12.995 -2.581  40.883  1   20.385 ? 251  HIS A NE2 1 
ATOM   1828 N  N   . ASP A 1 260 ? -15.732 -3.666  45.165  1   19.983 ? 252  ASP A N   1 
ATOM   1829 C  CA  . ASP A 1 260 ? -14.633 -4.04   46.038  1   19.921 ? 252  ASP A CA  1 
ATOM   1830 C  C   . ASP A 1 260 ? -15.196 -4.346  47.435  1   20.727 ? 252  ASP A C   1 
ATOM   1831 O  O   . ASP A 1 260 ? -16.382 -4.137  47.729  1   19.735 ? 252  ASP A O   1 
ATOM   1832 C  CB  . ASP A 1 260 ? -13.58  -2.936  46      1   21.547 ? 252  ASP A CB  1 
ATOM   1833 C  CG  . ASP A 1 260 ? -12.168 -3.278  46.485  1   19.794 ? 252  ASP A CG  1 
ATOM   1834 O  OD1 . ASP A 1 260 ? -11.918 -4.447  46.875  1   19.356 ? 252  ASP A OD1 1 
ATOM   1835 O  OD2 . ASP A 1 260 ? -11.285 -2.388  46.392  1   21.756 ? 252  ASP A OD2 1 
ATOM   1836 N  N   . CYS A 1 261 ? -14.283 -4.736  48.318  1   18.579 ? 253  CYS A N   1 
ATOM   1837 C  CA  . CYS A 1 261 ? -14.627 -5.165  49.655  1   18.483 ? 253  CYS A CA  1 
ATOM   1838 C  C   . CYS A 1 261 ? -13.395 -4.986  50.53   1   22.242 ? 253  CYS A C   1 
ATOM   1839 O  O   . CYS A 1 261 ? -12.303 -4.596  50.059  1   20.023 ? 253  CYS A O   1 
ATOM   1840 C  CB  . CYS A 1 261 ? -15.14  -6.608  49.613  1   20.712 ? 253  CYS A CB  1 
ATOM   1841 S  SG  . CYS A 1 261 ? -13.868 -7.782  49.071  1   22.875 ? 253  CYS A SG  1 
ATOM   1842 N  N   . ALA A 1 262 ? -13.586 -5.277  51.836  1   21.646 ? 254  ALA A N   1 
ATOM   1843 C  CA  . ALA A 1 262 ? -12.433 -5.304  52.74   1   23.237 ? 254  ALA A CA  1 
ATOM   1844 C  C   . ALA A 1 262 ? -12.506 -6.554  53.599  1   21.185 ? 254  ALA A C   1 
ATOM   1845 O  O   . ALA A 1 262 ? -13.602 -6.923  54.055  1   24.27  ? 254  ALA A O   1 
ATOM   1846 C  CB  . ALA A 1 262 ? -12.39  -4.054  53.589  1   22.062 ? 254  ALA A CB  1 
ATOM   1847 N  N   . LEU A 1 263 ? -11.34  -7.193  53.789  1   22.421 ? 255  LEU A N   1 
ATOM   1848 C  CA  . LEU A 1 263 ? -11.262 -8.364  54.642  1   21.004 ? 255  LEU A CA  1 
ATOM   1849 C  C   . LEU A 1 263 ? -10.692 -7.943  55.992  1   21.83  ? 255  LEU A C   1 
ATOM   1850 O  O   . LEU A 1 263 ? -9.711  -7.228  56.029  1   21.876 ? 255  LEU A O   1 
ATOM   1851 C  CB  . LEU A 1 263 ? -10.39  -9.427  53.991  1   21.818 ? 255  LEU A CB  1 
ATOM   1852 C  CG  . LEU A 1 263 ? -10.251 -10.748 54.762  1   22.67  ? 255  LEU A CG  1 
ATOM   1853 C  CD1 . LEU A 1 263 ? -11.553 -11.54  54.772  1   22.193 ? 255  LEU A CD1 1 
ATOM   1854 C  CD2 . LEU A 1 263 ? -9.079  -11.571 54.199  1   24.822 ? 255  LEU A CD2 1 
ATOM   1855 N  N   . THR A 1 264 ? -11.334 -8.421  57.059  1   24.301 ? 256  THR A N   1 
ATOM   1856 C  CA  . THR A 1 264 ? -10.809 -8.307  58.411  1   26.02  ? 256  THR A CA  1 
ATOM   1857 C  C   . THR A 1 264 ? -10.775 -9.702  59.051  1   26.8   ? 256  THR A C   1 
ATOM   1858 O  O   . THR A 1 264 ? -11.259 -10.681 58.458  1   23.315 ? 256  THR A O   1 
ATOM   1859 C  CB  . THR A 1 264 ? -11.658 -7.317  59.219  1   29.434 ? 256  THR A CB  1 
ATOM   1860 O  OG1 . THR A 1 264 ? -12.848 -7.971  59.677  1   26.459 ? 256  THR A OG1 1 
ATOM   1861 C  CG2 . THR A 1 264 ? -11.942 -6.005  58.505  1   27.014 ? 256  THR A CG2 1 
ATOM   1862 N  N   . PRO A 1 265 ? -10.24  -9.872  60.304  1   25.048 ? 257  PRO A N   1 
ATOM   1863 C  CA  . PRO A 1 265 ? -10.174 -11.212 60.879  1   24.574 ? 257  PRO A CA  1 
ATOM   1864 C  C   . PRO A 1 265 ? -11.501 -11.929 60.951  1   23.041 ? 257  PRO A C   1 
ATOM   1865 O  O   . PRO A 1 265 ? -11.545 -13.155 60.763  1   27.076 ? 257  PRO A O   1 
ATOM   1866 C  CB  . PRO A 1 265 ? -9.5    -11.007 62.252  1   31.237 ? 257  PRO A CB  1 
ATOM   1867 C  CG  . PRO A 1 265 ? -8.577  -9.832  61.911  1   26.199 ? 257  PRO A CG  1 
ATOM   1868 C  CD  . PRO A 1 265 ? -9.467  -8.901  61.096  1   27.252 ? 257  PRO A CD  1 
ATOM   1869 N  N   . ASN A 1 266 ? -12.569 -11.153 61.192  1   22.354 ? 258  ASN A N   1 
ATOM   1870 C  CA  . ASN A 1 266 ? -13.876 -11.721 61.496  1   23.781 ? 258  ASN A CA  1 
ATOM   1871 C  C   . ASN A 1 266 ? -14.946 -11.399 60.455  1   24.727 ? 258  ASN A C   1 
ATOM   1872 O  O   . ASN A 1 266 ? -16.07  -11.911 60.581  1   23.248 ? 258  ASN A O   1 
ATOM   1873 C  CB  . ASN A 1 266 ? -14.338 -11.294 62.888  1   24.65  ? 258  ASN A CB  1 
ATOM   1874 C  CG  . ASN A 1 266 ? -13.371 -11.819 63.929  1   30.639 ? 258  ASN A CG  1 
ATOM   1875 O  OD1 . ASN A 1 266 ? -13.1   -13.03  63.964  1   31.99  ? 258  ASN A OD1 1 
ATOM   1876 N  ND2 . ASN A 1 266 ? -12.782 -10.923 64.711  1   27.204 ? 258  ASN A ND2 1 
ATOM   1877 N  N   . TYR A 1 267 ? -14.617 -10.582 59.423  1   23.897 ? 259  TYR A N   1 
ATOM   1878 C  CA  . TYR A 1 267 ? -15.669 -10.105 58.52   1   21.597 ? 259  TYR A CA  1 
ATOM   1879 C  C   . TYR A 1 267 ? -15.152 -9.991  57.093  1   24.627 ? 259  TYR A C   1 
ATOM   1880 O  O   . TYR A 1 267 ? -13.975 -9.717  56.865  1   25.039 ? 259  TYR A O   1 
ATOM   1881 C  CB  . TYR A 1 267 ? -16.123 -8.665  58.825  1   22.651 ? 259  TYR A CB  1 
ATOM   1882 C  CG  . TYR A 1 267 ? -16.894 -8.516  60.132  1   22.236 ? 259  TYR A CG  1 
ATOM   1883 C  CD1 . TYR A 1 267 ? -18.277 -8.711  60.137  1   22.686 ? 259  TYR A CD1 1 
ATOM   1884 C  CD2 . TYR A 1 267 ? -16.23  -8.251  61.335  1   25.001 ? 259  TYR A CD2 1 
ATOM   1885 C  CE1 . TYR A 1 267 ? -19.018 -8.61   61.312  1   26.608 ? 259  TYR A CE1 1 
ATOM   1886 C  CE2 . TYR A 1 267 ? -16.967 -8.147  62.513  1   24.915 ? 259  TYR A CE2 1 
ATOM   1887 C  CZ  . TYR A 1 267 ? -18.345 -8.336  62.493  1   27.793 ? 259  TYR A CZ  1 
ATOM   1888 O  OH  . TYR A 1 267 ? -19.104 -8.188  63.628  1   29.984 ? 259  TYR A OH  1 
ATOM   1889 N  N   . LEU A 1 268 ? -16.07  -10.203 56.146  1   23.296 ? 260  LEU A N   1 
ATOM   1890 C  CA  . LEU A 1 268 ? -15.891 -9.629  54.813  1   21.364 ? 260  LEU A CA  1 
ATOM   1891 C  C   . LEU A 1 268 ? -16.847 -8.458  54.743  1   21.011 ? 260  LEU A C   1 
ATOM   1892 O  O   . LEU A 1 268 ? -18.027 -8.632  55.05   1   20.832 ? 260  LEU A O   1 
ATOM   1893 C  CB  . LEU A 1 268 ? -16.204 -10.637 53.698  1   21.791 ? 260  LEU A CB  1 
ATOM   1894 C  CG  . LEU A 1 268 ? -15.927 -10.117 52.278  1   18.944 ? 260  LEU A CG  1 
ATOM   1895 C  CD1 . LEU A 1 268 ? -14.434 -9.871  52.081  1   21.128 ? 260  LEU A CD1 1 
ATOM   1896 C  CD2 . LEU A 1 268 ? -16.444 -11.238 51.326  1   19.255 ? 260  LEU A CD2 1 
ATOM   1897 N  N   . VAL A 1 269 ? -16.335 -7.297  54.299  1   21.127 ? 261  VAL A N   1 
ATOM   1898 C  CA  . VAL A 1 269 ? -17.19  -6.115  54.257  1   20.329 ? 261  VAL A CA  1 
ATOM   1899 C  C   . VAL A 1 269 ? -17.354 -5.67   52.8    1   22.281 ? 261  VAL A C   1 
ATOM   1900 O  O   . VAL A 1 269 ? -16.371 -5.283  52.193  1   22.52  ? 261  VAL A O   1 
ATOM   1901 C  CB  . VAL A 1 269 ? -16.671 -4.969  55.139  1   20.066 ? 261  VAL A CB  1 
ATOM   1902 C  CG1 . VAL A 1 269 ? -17.714 -3.844  55.225  1   20.568 ? 261  VAL A CG1 1 
ATOM   1903 C  CG2 . VAL A 1 269 ? -16.26  -5.456  56.531  1   20.446 ? 261  VAL A CG2 1 
ATOM   1904 N  N   . LEU A 1 270 ? -18.582 -5.704  52.288  1   20.381 ? 262  LEU A N   1 
ATOM   1905 C  CA  . LEU A 1 270 ? -18.811 -5.322  50.9    1   21.297 ? 262  LEU A CA  1 
ATOM   1906 C  C   . LEU A 1 270 ? -19.036 -3.826  50.8    1   21.952 ? 262  LEU A C   1 
ATOM   1907 O  O   . LEU A 1 270 ? -19.76  -3.267  51.608  1   23.511 ? 262  LEU A O   1 
ATOM   1908 C  CB  . LEU A 1 270 ? -20.037 -6.03   50.35   1   19.906 ? 262  LEU A CB  1 
ATOM   1909 C  CG  . LEU A 1 270 ? -20.065 -7.56   50.484  1   25.972 ? 262  LEU A CG  1 
ATOM   1910 C  CD1 . LEU A 1 270 ? -21.203 -8.188  49.73   1   23.962 ? 262  LEU A CD1 1 
ATOM   1911 C  CD2 . LEU A 1 270 ? -18.747 -8.229  50.157  1   24.003 ? 262  LEU A CD2 1 
ATOM   1912 N  N   . MET A 1 271 ? -18.573 -3.234  49.694  1   19.67  ? 263  MET A N   1 
ATOM   1913 C  CA  . MET A 1 271 ? -18.684 -1.777  49.544  1   20.617 ? 263  MET A CA  1 
ATOM   1914 C  C   . MET A 1 271 ? -19.607 -1.483  48.362  1   19.19  ? 263  MET A C   1 
ATOM   1915 O  O   . MET A 1 271 ? -19.242 -1.768  47.243  1   20.696 ? 263  MET A O   1 
ATOM   1916 C  CB  . MET A 1 271 ? -17.275 -1.187  49.375  1   19.498 ? 263  MET A CB  1 
ATOM   1917 C  CG  . MET A 1 271 ? -17.202 0.354   49.264  1   20.553 ? 263  MET A CG  1 
ATOM   1918 S  SD  . MET A 1 271 ? -15.476 0.886   49.367  1   25.03  ? 263  MET A SD  1 
ATOM   1919 C  CE  . MET A 1 271 ? -14.71  0.244   47.844  1   24.891 ? 263  MET A CE  1 
ATOM   1920 N  N   . LEU A 1 272 ? -20.773 -0.885  48.612  1   21.198 ? 264  LEU A N   1 
ATOM   1921 C  CA  . LEU A 1 272 ? -21.752 -0.649  47.554  1   20.723 ? 264  LEU A CA  1 
ATOM   1922 C  C   . LEU A 1 272 ? -21.559 0.759   46.996  1   21.001 ? 264  LEU A C   1 
ATOM   1923 O  O   . LEU A 1 272 ? -21.723 1.726   47.72   1   23.087 ? 264  LEU A O   1 
ATOM   1924 C  CB  . LEU A 1 272 ? -23.199 -0.826  48.03   1   21.741 ? 264  LEU A CB  1 
ATOM   1925 C  CG  . LEU A 1 272 ? -23.691 -2.263  48.225  1   22.1   ? 264  LEU A CG  1 
ATOM   1926 C  CD1 . LEU A 1 272 ? -22.854 -3.082  49.226  1   24.45  ? 264  LEU A CD1 1 
ATOM   1927 C  CD2 . LEU A 1 272 ? -25.173 -2.207  48.665  1   22.613 ? 264  LEU A CD2 1 
ATOM   1928 N  N   . TRP A 1 273 ? -21.363 0.851   45.671  1   18.805 ? 265  TRP A N   1 
ATOM   1929 C  CA  . TRP A 1 273 ? -21.399 2.112   44.954  1   18.932 ? 265  TRP A CA  1 
ATOM   1930 C  C   . TRP A 1 273 ? -22.841 2.514   44.679  1   19.695 ? 265  TRP A C   1 
ATOM   1931 O  O   . TRP A 1 273 ? -23.71  1.649   44.527  1   21.294 ? 265  TRP A O   1 
ATOM   1932 C  CB  . TRP A 1 273 ? -20.689 1.98    43.595  1   18.629 ? 265  TRP A CB  1 
ATOM   1933 C  CG  . TRP A 1 273 ? -19.202 1.749   43.716  1   19.916 ? 265  TRP A CG  1 
ATOM   1934 C  CD1 . TRP A 1 273 ? -18.39  1.754   44.805  1   21.827 ? 265  TRP A CD1 1 
ATOM   1935 C  CD2 . TRP A 1 273 ? -18.363 1.51    42.579  1   19.504 ? 265  TRP A CD2 1 
ATOM   1936 N  NE1 . TRP A 1 273 ? -17.089 1.477   44.432  1   20.192 ? 265  TRP A NE1 1 
ATOM   1937 C  CE2 . TRP A 1 273 ? -17.043 1.349   43.063  1   19.672 ? 265  TRP A CE2 1 
ATOM   1938 C  CE3 . TRP A 1 273 ? -18.615 1.399   41.205  1   22.111 ? 265  TRP A CE3 1 
ATOM   1939 C  CZ2 . TRP A 1 273 ? -15.968 1.092   42.207  1   20.4   ? 265  TRP A CZ2 1 
ATOM   1940 C  CZ3 . TRP A 1 273 ? -17.546 1.174   40.349  1   21.276 ? 265  TRP A CZ3 1 
ATOM   1941 C  CH2 . TRP A 1 273 ? -16.244 1.008   40.852  1   21.477 ? 265  TRP A CH2 1 
ATOM   1942 N  N   . PRO A 1 274 ? -23.098 3.84    44.548  1   20.36  ? 266  PRO A N   1 
ATOM   1943 C  CA  . PRO A 1 274 ? -24.453 4.339   44.315  1   21.38  ? 266  PRO A CA  1 
ATOM   1944 C  C   . PRO A 1 274 ? -24.85  4.26    42.838  1   21.739 ? 266  PRO A C   1 
ATOM   1945 O  O   . PRO A 1 274 ? -25.217 5.253   42.228  1   25.446 ? 266  PRO A O   1 
ATOM   1946 C  CB  . PRO A 1 274 ? -24.369 5.759   44.904  1   20.626 ? 266  PRO A CB  1 
ATOM   1947 C  CG  . PRO A 1 274 ? -22.947 6.183   44.501  1   20.48  ? 266  PRO A CG  1 
ATOM   1948 C  CD  . PRO A 1 274 ? -22.121 4.92    44.774  1   20.598 ? 266  PRO A CD  1 
ATOM   1949 N  N   . PHE A 1 275 ? -24.766 3.057   42.282  1   19.557 ? 267  PHE A N   1 
ATOM   1950 C  CA  . PHE A 1 275 ? -25.352 2.797   40.978  1   19.6   ? 267  PHE A CA  1 
ATOM   1951 C  C   . PHE A 1 275 ? -26.414 1.731   41.211  1   20.755 ? 267  PHE A C   1 
ATOM   1952 O  O   . PHE A 1 275 ? -26.245 0.874   42.081  1   21.046 ? 267  PHE A O   1 
ATOM   1953 C  CB  . PHE A 1 275 ? -24.337 2.201   39.989  1   19.589 ? 267  PHE A CB  1 
ATOM   1954 C  CG  . PHE A 1 275 ? -23.203 3.141   39.619  1   20.37  ? 267  PHE A CG  1 
ATOM   1955 C  CD1 . PHE A 1 275 ? -22.101 3.295   40.48   1   20.031 ? 267  PHE A CD1 1 
ATOM   1956 C  CD2 . PHE A 1 275 ? -23.244 3.858   38.414  1   20.412 ? 267  PHE A CD2 1 
ATOM   1957 C  CE1 . PHE A 1 275 ? -21.057 4.196   40.181  1   21.918 ? 267  PHE A CE1 1 
ATOM   1958 C  CE2 . PHE A 1 275 ? -22.192 4.748   38.103  1   20.266 ? 267  PHE A CE2 1 
ATOM   1959 C  CZ  . PHE A 1 275 ? -21.075 4.866   38.966  1   22.026 ? 267  PHE A CZ  1 
ATOM   1960 N  N   . GLU A 1 276 ? -27.464 1.776   40.393  1   20.31  ? 268  GLU A N   1 
ATOM   1961 C  CA  . GLU A 1 276 ? -28.473 0.73    40.452  1   19.956 ? 268  GLU A CA  1 
ATOM   1962 C  C   . GLU A 1 276 ? -28.684 0.18    39.053  1   23.179 ? 268  GLU A C   1 
ATOM   1963 O  O   . GLU A 1 276 ? -28.594 0.925   38.066  1   24.998 ? 268  GLU A O   1 
ATOM   1964 C  CB  . GLU A 1 276 ? -29.757 1.337   41.047  1   22.846 ? 268  GLU A CB  1 
ATOM   1965 C  CG  . GLU A 1 276 ? -30.893 0.314   41.203  1   23.65  ? 268  GLU A CG  1 
ATOM   1966 C  CD  . GLU A 1 276 ? -32     0.8     42.134  1   28.65  ? 268  GLU A CD  1 
ATOM   1967 O  OE1 . GLU A 1 276 ? -32.068 2.029   42.421  1   30.202 ? 268  GLU A OE1 1 
ATOM   1968 O  OE2 . GLU A 1 276 ? -32.796 -0.056  42.568  1   27.909 ? 268  GLU A OE2 1 
ATOM   1969 N  N   . ALA A 1 277 ? -28.924 -1.141  39      1   22.553 ? 269  ALA A N   1 
ATOM   1970 C  CA  . ALA A 1 277 ? -29.221 -1.825  37.744  1   21.751 ? 269  ALA A CA  1 
ATOM   1971 C  C   . ALA A 1 277 ? -30.732 -1.828  37.532  1   24.222 ? 269  ALA A C   1 
ATOM   1972 O  O   . ALA A 1 277 ? -31.491 -1.951  38.495  1   28.503 ? 269  ALA A O   1 
ATOM   1973 C  CB  . ALA A 1 277 ? -28.732 -3.261  37.819  1   23.363 ? 269  ALA A CB  1 
ATOM   1974 N  N   . ASN A 1 278 ? -31.144 -1.822  36.261  1   23.922 ? 270  ASN A N   1 
ATOM   1975 C  CA  . ASN A 1 278 ? -32.555 -1.807  35.944  1   24.816 ? 270  ASN A CA  1 
ATOM   1976 C  C   . ASN A 1 278 ? -32.715 -2.671  34.704  1   21.367 ? 270  ASN A C   1 
ATOM   1977 O  O   . ASN A 1 278 ? -32.219 -2.301  33.651  1   25.476 ? 270  ASN A O   1 
ATOM   1978 C  CB  . ASN A 1 278 ? -33.009 -0.366  35.73   1   26.589 ? 270  ASN A CB  1 
ATOM   1979 C  CG  . ASN A 1 278 ? -34.5   -0.284  35.498  1   29.271 ? 270  ASN A CG  1 
ATOM   1980 O  OD1 . ASN A 1 278 ? -34.991 -0.677  34.44   1   27.668 ? 270  ASN A OD1 1 
ATOM   1981 N  ND2 . ASN A 1 278 ? -35.216 0.254   36.47   1   35.806 ? 270  ASN A ND2 1 
ATOM   1982 N  N   . LEU A 1 279 ? -33.41  -3.803  34.862  1   22.953 ? 271  LEU A N   1 
ATOM   1983 C  CA  . LEU A 1 279 ? -33.644 -4.737  33.769  1   21.318 ? 271  LEU A CA  1 
ATOM   1984 C  C   . LEU A 1 279 ? -34.439 -4.096  32.629  1   22.254 ? 271  LEU A C   1 
ATOM   1985 O  O   . LEU A 1 279 ? -34.115 -4.318  31.459  1   21.666 ? 271  LEU A O   1 
ATOM   1986 C  CB  . LEU A 1 279 ? -34.327 -5.984  34.358  1   24.082 ? 271  LEU A CB  1 
ATOM   1987 C  CG  . LEU A 1 279 ? -34.417 -7.168  33.398  1   23.055 ? 271  LEU A CG  1 
ATOM   1988 C  CD1 . LEU A 1 279 ? -33.025 -7.695  33.016  1   24.458 ? 271  LEU A CD1 1 
ATOM   1989 C  CD2 . LEU A 1 279 ? -35.201 -8.323  34.077  1   27.039 ? 271  LEU A CD2 1 
ATOM   1990 N  N   . GLU A 1 280 ? -35.472 -3.297  32.947  1   24.658 ? 272  GLU A N   1 
ATOM   1991 C  CA  . GLU A 1 280 ? -36.287 -2.66   31.909  1   27.191 ? 272  GLU A CA  1 
ATOM   1992 C  C   . GLU A 1 280 ? -35.447 -1.701  31.051  1   26.235 ? 272  GLU A C   1 
ATOM   1993 O  O   . GLU A 1 280 ? -35.59  -1.685  29.826  1   28.553 ? 272  GLU A O   1 
ATOM   1994 C  CB  . GLU A 1 280 ? -37.51  -1.934  32.499  1   31.761 ? 272  GLU A CB  1 
ATOM   1995 C  CG  . GLU A 1 280 ? -38.638 -2.901  32.837  1   46.646 ? 272  GLU A CG  1 
ATOM   1996 C  CD  . GLU A 1 280 ? -39.365 -3.313  31.561  1   65.372 ? 272  GLU A CD  1 
ATOM   1997 O  OE1 . GLU A 1 280 ? -40.069 -2.437  30.999  1   73.784 ? 272  GLU A OE1 1 
ATOM   1998 O  OE2 . GLU A 1 280 ? -39.201 -4.469  31.091  1   64.188 ? 272  GLU A OE2 1 
ATOM   1999 N  N   . ARG A 1 281 ? -34.555 -0.939  31.703  1   24.169 ? 273  ARG A N   1 
ATOM   2000 C  CA  . ARG A 1 281 ? -33.636 -0.058  30.99   1   26.063 ? 273  ARG A CA  1 
ATOM   2001 C  C   . ARG A 1 281 ? -32.732 -0.876  30.07   1   24.13  ? 273  ARG A C   1 
ATOM   2002 O  O   . ARG A 1 281 ? -32.556 -0.502  28.9    1   24.309 ? 273  ARG A O   1 
ATOM   2003 C  CB  . ARG A 1 281 ? -32.779 0.821   31.916  1   26.885 ? 273  ARG A CB  1 
ATOM   2004 C  CG  . ARG A 1 281 ? -31.794 1.738   31.197  1   25.947 ? 273  ARG A CG  1 
ATOM   2005 C  CD  . ARG A 1 281 ? -31.065 2.659   32.167  1   26.121 ? 273  ARG A CD  1 
ATOM   2006 N  NE  . ARG A 1 281 ? -30.314 1.885   33.176  1   24.836 ? 273  ARG A NE  1 
ATOM   2007 C  CZ  . ARG A 1 281 ? -30.487 1.936   34.484  1   26.695 ? 273  ARG A CZ  1 
ATOM   2008 N  NH1 . ARG A 1 281 ? -31.354 2.789   35.001  1   27.181 ? 273  ARG A NH1 1 
ATOM   2009 N  NH2 . ARG A 1 281 ? -29.804 1.138   35.292  1   25.283 ? 273  ARG A NH2 1 
ATOM   2010 N  N   . MET A 1 282 ? -32.2   -2.009  30.572  1   22.596 ? 274  MET A N   1 
ATOM   2011 C  CA  . MET A 1 282 ? -31.361 -2.834  29.723  1   21.006 ? 274  MET A CA  1 
ATOM   2012 C  C   . MET A 1 282 ? -32.127 -3.363  28.518  1   22.143 ? 274  MET A C   1 
ATOM   2013 O  O   . MET A 1 282 ? -31.629 -3.329  27.386  1   20.679 ? 274  MET A O   1 
ATOM   2014 C  CB  . MET A 1 282 ? -30.727 -3.992  30.515  1   21.884 ? 274  MET A CB  1 
ATOM   2015 C  CG  . MET A 1 282 ? -29.759 -3.424  31.582  1   24.622 ? 274  MET A CG  1 
ATOM   2016 S  SD  . MET A 1 282 ? -28.965 -4.868  32.332  1   28.562 ? 274  MET A SD  1 
ATOM   2017 C  CE  . MET A 1 282 ? -29.413 -4.654  34.059  1   24.266 ? 274  MET A CE  1 
ATOM   2018 N  N   . LYS A 1 283 ? -33.352 -3.851  28.77   1   24.945 ? 275  LYS A N   1 
ATOM   2019 C  CA  . LYS A 1 283 ? -34.13  -4.417  27.673  1   24.843 ? 275  LYS A CA  1 
ATOM   2020 C  C   . LYS A 1 283 ? -34.419 -3.357  26.609  1   26.086 ? 275  LYS A C   1 
ATOM   2021 O  O   . LYS A 1 283 ? -34.474 -3.681  25.415  1   27.648 ? 275  LYS A O   1 
ATOM   2022 C  CB  . LYS A 1 283 ? -35.424 -5.048  28.202  1   24.99  ? 275  LYS A CB  1 
ATOM   2023 C  CG  . LYS A 1 283 ? -35.18  -6.384  28.935  1   26.128 ? 275  LYS A CG  1 
ATOM   2024 C  CD  . LYS A 1 283 ? -36.51  -6.872  29.519  1   27.322 ? 275  LYS A CD  1 
ATOM   2025 C  CE  . LYS A 1 283 ? -36.39  -8.238  30.137  1   27.169 ? 275  LYS A CE  1 
ATOM   2026 N  NZ  . LYS A 1 283 ? -37.676 -8.603  30.746  1   26.727 ? 275  LYS A NZ  1 
ATOM   2027 N  N   . ALA A 1 284 ? -34.504 -2.101  27.035  1   25.624 ? 276  ALA A N   1 
ATOM   2028 C  CA  . ALA A 1 284 ? -34.725 -0.98   26.121  1   30.665 ? 276  ALA A CA  1 
ATOM   2029 C  C   . ALA A 1 284 ? -33.434 -0.522  25.435  1   35.159 ? 276  ALA A C   1 
ATOM   2030 O  O   . ALA A 1 284 ? -33.455 0.456   24.693  1   32.221 ? 276  ALA A O   1 
ATOM   2031 C  CB  . ALA A 1 284 ? -35.369 0.143   26.887  1   32.746 ? 276  ALA A CB  1 
ATOM   2032 N  N   . GLY A 1 285 ? -32.3   -1.18   25.721  1   28.142 ? 277  GLY A N   1 
ATOM   2033 C  CA  . GLY A 1 285 ? -31.066 -0.896  25.003  1   26.629 ? 277  GLY A CA  1 
ATOM   2034 C  C   . GLY A 1 285 ? -30.203 0.139   25.73   1   29.385 ? 277  GLY A C   1 
ATOM   2035 O  O   . GLY A 1 285 ? -29.242 0.619   25.152  1   27.647 ? 277  GLY A O   1 
ATOM   2036 N  N   . GLY A 1 286 ? -30.519 0.415   26.999  1   25.607 ? 278  GLY A N   1 
ATOM   2037 C  CA  . GLY A 1 286 ? -29.807 1.362   27.845  1   24.306 ? 278  GLY A CA  1 
ATOM   2038 C  C   . GLY A 1 286 ? -28.723 0.669   28.679  1   24.462 ? 278  GLY A C   1 
ATOM   2039 O  O   . GLY A 1 286 ? -28.59  -0.545  28.637  1   24.494 ? 278  GLY A O   1 
ATOM   2040 N  N   . HIS A 1 287 ? -27.962 1.454   29.443  1   21.863 ? 279  HIS A N   1 
ATOM   2041 C  CA  . HIS A 1 287 ? -26.869 0.888   30.235  1   22.827 ? 279  HIS A CA  1 
ATOM   2042 C  C   . HIS A 1 287 ? -27.372 0.064   31.416  1   25.384 ? 279  HIS A C   1 
ATOM   2043 O  O   . HIS A 1 287 ? -28.473 0.248   31.964  1   23.56  ? 279  HIS A O   1 
ATOM   2044 C  CB  . HIS A 1 287 ? -25.957 2.01    30.743  1   21.6   ? 279  HIS A CB  1 
ATOM   2045 C  CG  . HIS A 1 287 ? -24.983 2.496   29.733  1   22.831 ? 279  HIS A CG  1 
ATOM   2046 N  ND1 . HIS A 1 287 ? -24.062 1.674   29.119  1   24.507 ? 279  HIS A ND1 1 
ATOM   2047 C  CD2 . HIS A 1 287 ? -24.695 3.749   29.354  1   23.835 ? 279  HIS A CD2 1 
ATOM   2048 C  CE1 . HIS A 1 287 ? -23.279 2.403   28.335  1   25.559 ? 279  HIS A CE1 1 
ATOM   2049 N  NE2 . HIS A 1 287 ? -23.652 3.677   28.474  1   24.298 ? 279  HIS A NE2 1 
ATOM   2050 N  N   . HIS A 1 288 ? -26.517 -0.894  31.801  1   21.647 ? 280  HIS A N   1 
ATOM   2051 C  CA  . HIS A 1 288 ? -26.741 -1.719  32.977  1   21.855 ? 280  HIS A CA  1 
ATOM   2052 C  C   . HIS A 1 288 ? -26.962 -0.856  34.225  1   20.849 ? 280  HIS A C   1 
ATOM   2053 O  O   . HIS A 1 288 ? -27.937 -1.058  34.949  1   23.022 ? 280  HIS A O   1 
ATOM   2054 C  CB  . HIS A 1 288 ? -25.569 -2.699  33.112  1   19.7   ? 280  HIS A CB  1 
ATOM   2055 C  CG  . HIS A 1 288 ? -25.771 -3.733  34.173  1   19.544 ? 280  HIS A CG  1 
ATOM   2056 N  ND1 . HIS A 1 288 ? -25.908 -5.063  33.849  1   19.591 ? 280  HIS A ND1 1 
ATOM   2057 C  CD2 . HIS A 1 288 ? -25.824 -3.672  35.53   1   19.127 ? 280  HIS A CD2 1 
ATOM   2058 C  CE1 . HIS A 1 288 ? -26.026 -5.789  34.96   1   19.292 ? 280  HIS A CE1 1 
ATOM   2059 N  NE2 . HIS A 1 288 ? -26.008 -4.97   35.991  1   20.4   ? 280  HIS A NE2 1 
ATOM   2060 N  N   . TRP A 1 289 ? -26.058 0.09    34.457  1   21.106 ? 281  TRP A N   1 
ATOM   2061 C  CA  . TRP A 1 289 ? -25.954 0.898   35.65   1   20.523 ? 281  TRP A CA  1 
ATOM   2062 C  C   . TRP A 1 289 ? -26.364 2.325   35.335  1   23.012 ? 281  TRP A C   1 
ATOM   2063 O  O   . TRP A 1 289 ? -26.04  2.823   34.265  1   22.473 ? 281  TRP A O   1 
ATOM   2064 C  CB  . TRP A 1 289 ? -24.483 0.932   36.121  1   20.145 ? 281  TRP A CB  1 
ATOM   2065 C  CG  . TRP A 1 289 ? -23.959 -0.395  36.57   1   19.663 ? 281  TRP A CG  1 
ATOM   2066 C  CD1 . TRP A 1 289 ? -22.943 -1.08   35.989  1   21.287 ? 281  TRP A CD1 1 
ATOM   2067 C  CD2 . TRP A 1 289 ? -24.427 -1.208  37.666  1   21.885 ? 281  TRP A CD2 1 
ATOM   2068 N  NE1 . TRP A 1 289 ? -22.691 -2.244  36.659  1   19.074 ? 281  TRP A NE1 1 
ATOM   2069 C  CE2 . TRP A 1 289 ? -23.6   -2.358  37.69   1   19.909 ? 281  TRP A CE2 1 
ATOM   2070 C  CE3 . TRP A 1 289 ? -25.465 -1.084  38.609  1   21.893 ? 281  TRP A CE3 1 
ATOM   2071 C  CZ2 . TRP A 1 289 ? -23.8   -3.389  38.619  1   21.363 ? 281  TRP A CZ2 1 
ATOM   2072 C  CZ3 . TRP A 1 289 ? -25.656 -2.08   39.55   1   19.987 ? 281  TRP A CZ3 1 
ATOM   2073 C  CH2 . TRP A 1 289 ? -24.833 -3.233  39.534  1   22.369 ? 281  TRP A CH2 1 
ATOM   2074 N  N   . ALA A 1 290 ? -26.95  2.993   36.346  1   21.084 ? 282  ALA A N   1 
ATOM   2075 C  CA  . ALA A 1 290 ? -27.143 4.44    36.328  1   22.372 ? 282  ALA A CA  1 
ATOM   2076 C  C   . ALA A 1 290 ? -26.75  4.929   37.715  1   21.053 ? 282  ALA A C   1 
ATOM   2077 O  O   . ALA A 1 290 ? -27.18  4.366   38.72   1   23.257 ? 282  ALA A O   1 
ATOM   2078 C  CB  . ALA A 1 290 ? -28.604 4.744   35.989  1   23.147 ? 282  ALA A CB  1 
ATOM   2079 N  N   . TYR A 1 291 ? -25.921 5.981   37.767  1   20.268 ? 283  TYR A N   1 
ATOM   2080 C  CA  . TYR A 1 291 ? -25.554 6.578   39.042  1   22.046 ? 283  TYR A CA  1 
ATOM   2081 C  C   . TYR A 1 291 ? -26.792 7.197   39.68   1   25.336 ? 283  TYR A C   1 
ATOM   2082 O  O   . TYR A 1 291 ? -27.657 7.704   38.986  1   22.969 ? 283  TYR A O   1 
ATOM   2083 C  CB  . TYR A 1 291 ? -24.501 7.666   38.795  1   22.286 ? 283  TYR A CB  1 
ATOM   2084 C  CG  . TYR A 1 291 ? -23.883 8.223   40.07   1   22.271 ? 283  TYR A CG  1 
ATOM   2085 C  CD1 . TYR A 1 291 ? -24.439 9.305   40.768  1   23.778 ? 283  TYR A CD1 1 
ATOM   2086 C  CD2 . TYR A 1 291 ? -22.712 7.656   40.564  1   21.93  ? 283  TYR A CD2 1 
ATOM   2087 C  CE1 . TYR A 1 291 ? -23.828 9.784   41.938  1   23.981 ? 283  TYR A CE1 1 
ATOM   2088 C  CE2 . TYR A 1 291 ? -22.073 8.156   41.695  1   23.406 ? 283  TYR A CE2 1 
ATOM   2089 C  CZ  . TYR A 1 291 ? -22.637 9.221   42.392  1   25.623 ? 283  TYR A CZ  1 
ATOM   2090 O  OH  . TYR A 1 291 ? -22.012 9.645   43.541  1   27.865 ? 283  TYR A OH  1 
ATOM   2091 N  N   . ASP A 1 292 ? -26.878 7.096   41.009  1   21.845 ? 284  ASP A N   1 
ATOM   2092 C  CA  . ASP A 1 292 ? -28.023 7.66    41.706  1   25.009 ? 284  ASP A CA  1 
ATOM   2093 C  C   . ASP A 1 292 ? -27.524 8.499   42.865  1   26.298 ? 284  ASP A C   1 
ATOM   2094 O  O   . ASP A 1 292 ? -27.099 7.94    43.864  1   26.354 ? 284  ASP A O   1 
ATOM   2095 C  CB  . ASP A 1 292 ? -29.014 6.58    42.097  1   25.382 ? 284  ASP A CB  1 
ATOM   2096 C  CG  . ASP A 1 292 ? -30.261 7.058   42.828  1   29.147 ? 284  ASP A CG  1 
ATOM   2097 O  OD1 . ASP A 1 292 ? -30.371 8.269   43.139  1   27.147 ? 284  ASP A OD1 1 
ATOM   2098 O  OD2 . ASP A 1 292 ? -31.097 6.207   43.075  1   27.246 ? 284  ASP A OD2 1 
ATOM   2099 N  N   . TYR A 1 293 ? -27.638 9.839   42.744  1   25.923 ? 285  TYR A N   1 
ATOM   2100 C  CA  . TYR A 1 293 ? -27.201 10.741  43.802  1   24.991 ? 285  TYR A CA  1 
ATOM   2101 C  C   . TYR A 1 293 ? -27.967 10.533  45.108  1   24.307 ? 285  TYR A C   1 
ATOM   2102 O  O   . TYR A 1 293 ? -27.487 10.965  46.148  1   27.92  ? 285  TYR A O   1 
ATOM   2103 C  CB  . TYR A 1 293 ? -27.404 12.188  43.344  1   27.276 ? 285  TYR A CB  1 
ATOM   2104 C  CG  . TYR A 1 293 ? -26.279 12.609  42.416  1   28.318 ? 285  TYR A CG  1 
ATOM   2105 C  CD1 . TYR A 1 293 ? -25.039 13.04   42.904  1   31.22  ? 285  TYR A CD1 1 
ATOM   2106 C  CD2 . TYR A 1 293 ? -26.472 12.56   41.035  1   30.512 ? 285  TYR A CD2 1 
ATOM   2107 C  CE1 . TYR A 1 293 ? -24.012 13.407  42.028  1   31.106 ? 285  TYR A CE1 1 
ATOM   2108 C  CE2 . TYR A 1 293 ? -25.47  12.932  40.152  1   31.569 ? 285  TYR A CE2 1 
ATOM   2109 C  CZ  . TYR A 1 293 ? -24.247 13.355  40.653  1   38.479 ? 285  TYR A CZ  1 
ATOM   2110 O  OH  . TYR A 1 293 ? -23.298 13.687  39.744  1   46.517 ? 285  TYR A OH  1 
ATOM   2111 N  N   . THR A 1 294 ? -29.141 9.864   45.065  1   27.739 ? 286  THR A N   1 
ATOM   2112 C  CA  . THR A 1 294 ? -29.937 9.64    46.272  1   28.364 ? 286  THR A CA  1 
ATOM   2113 C  C   . THR A 1 294 ? -29.503 8.406   47.06   1   31.87  ? 286  THR A C   1 
ATOM   2114 O  O   . THR A 1 294 ? -29.929 8.243   48.199  1   29.052 ? 286  THR A O   1 
ATOM   2115 C  CB  . THR A 1 294 ? -31.449 9.666   46.023  1   29.864 ? 286  THR A CB  1 
ATOM   2116 O  OG1 . THR A 1 294 ? -31.808 8.427   45.412  1   29.593 ? 286  THR A OG1 1 
ATOM   2117 C  CG2 . THR A 1 294 ? -31.876 10.949  45.322  1   30.509 ? 286  THR A CG2 1 
ATOM   2118 N  N   . LYS A 1 295 ? -28.638 7.568   46.488  1   27.03  ? 287  LYS A N   1 
ATOM   2119 C  CA  . LYS A 1 295 ? -28.186 6.373   47.182  1   28.498 ? 287  LYS A CA  1 
ATOM   2120 C  C   . LYS A 1 295 ? -27.022 6.715   48.099  1   24.643 ? 287  LYS A C   1 
ATOM   2121 O  O   . LYS A 1 295 ? -26.042 7.337   47.659  1   25.536 ? 287  LYS A O   1 
ATOM   2122 C  CB  . LYS A 1 295 ? -27.756 5.266   46.206  1   25.874 ? 287  LYS A CB  1 
ATOM   2123 C  CG  . LYS A 1 295 ? -28.885 4.642   45.421  1   28.517 ? 287  LYS A CG  1 
ATOM   2124 C  CD  . LYS A 1 295 ? -29.755 3.685   46.245  1   26.979 ? 287  LYS A CD  1 
ATOM   2125 C  CE  . LYS A 1 295 ? -30.856 3.024   45.485  1   30.781 ? 287  LYS A CE  1 
ATOM   2126 N  NZ  . LYS A 1 295 ? -31.894 3.969   45.118  1   37.763 ? 287  LYS A NZ  1 
ATOM   2127 N  N   . PRO A 1 296 ? -27.056 6.293   49.384  1   22.304 ? 288  PRO A N   1 
ATOM   2128 C  CA  . PRO A 1 296 ? -25.895 6.475   50.234  1   22.9   ? 288  PRO A CA  1 
ATOM   2129 C  C   . PRO A 1 296 ? -24.873 5.367   49.987  1   25.283 ? 288  PRO A C   1 
ATOM   2130 O  O   . PRO A 1 296 ? -25.262 4.235   49.67   1   25.084 ? 288  PRO A O   1 
ATOM   2131 C  CB  . PRO A 1 296 ? -26.491 6.378   51.637  1   22.779 ? 288  PRO A CB  1 
ATOM   2132 C  CG  . PRO A 1 296 ? -27.582 5.351   51.426  1   23.012 ? 288  PRO A CG  1 
ATOM   2133 C  CD  . PRO A 1 296 ? -28.168 5.616   50.071  1   24.724 ? 288  PRO A CD  1 
ATOM   2134 N  N   . ILE A 1 297 ? -23.592 5.68    50.205  1   22.663 ? 289  ILE A N   1 
ATOM   2135 C  CA  . ILE A 1 297 ? -22.589 4.626   50.276  1   23.205 ? 289  ILE A CA  1 
ATOM   2136 C  C   . ILE A 1 297 ? -23.072 3.642   51.339  1   25.82  ? 289  ILE A C   1 
ATOM   2137 O  O   . ILE A 1 297 ? -23.439 4.058   52.449  1   23.594 ? 289  ILE A O   1 
ATOM   2138 C  CB  . ILE A 1 297 ? -21.209 5.23    50.615  1   24.116 ? 289  ILE A CB  1 
ATOM   2139 C  CG1 . ILE A 1 297 ? -20.649 6.011   49.399  1   24.288 ? 289  ILE A CG1 1 
ATOM   2140 C  CG2 . ILE A 1 297 ? -20.207 4.147   51.047  1   24.073 ? 289  ILE A CG2 1 
ATOM   2141 C  CD1 . ILE A 1 297 ? -19.535 6.984   49.785  1   23.321 ? 289  ILE A CD1 1 
ATOM   2142 N  N   . THR A 1 298 ? -23.058 2.336   50.987  1   24.004 ? 290  THR A N   1 
ATOM   2143 C  CA  . THR A 1 298 ? -23.621 1.317   51.853  1   22.674 ? 290  THR A CA  1 
ATOM   2144 C  C   . THR A 1 298 ? -22.577 0.208   51.992  1   24.147 ? 290  THR A C   1 
ATOM   2145 O  O   . THR A 1 298 ? -21.86  -0.105  51.034  1   23.348 ? 290  THR A O   1 
ATOM   2146 C  CB  . THR A 1 298 ? -24.94  0.819   51.251  1   24.549 ? 290  THR A CB  1 
ATOM   2147 O  OG1 . THR A 1 298 ? -25.87  1.903   51.3    1   22.179 ? 290  THR A OG1 1 
ATOM   2148 C  CG2 . THR A 1 298 ? -25.606 -0.281  52.072  1   23.418 ? 290  THR A CG2 1 
ATOM   2149 N  N   . TRP A 1 299 ? -22.473 -0.331  53.206  1   21.209 ? 291  TRP A N   1 
ATOM   2150 C  CA  . TRP A 1 299 ? -21.572 -1.445  53.483  1   22.644 ? 291  TRP A CA  1 
ATOM   2151 C  C   . TRP A 1 299 ? -22.396 -2.637  53.958  1   26.776 ? 291  TRP A C   1 
ATOM   2152 O  O   . TRP A 1 299 ? -23.362 -2.449  54.712  1   27.977 ? 291  TRP A O   1 
ATOM   2153 C  CB  . TRP A 1 299 ? -20.565 -1.027  54.57   1   22.516 ? 291  TRP A CB  1 
ATOM   2154 C  CG  . TRP A 1 299 ? -19.759 0.202   54.234  1   26.803 ? 291  TRP A CG  1 
ATOM   2155 C  CD1 . TRP A 1 299 ? -20.14  1.5     54.435  1   26.982 ? 291  TRP A CD1 1 
ATOM   2156 C  CD2 . TRP A 1 299 ? -18.428 0.257   53.667  1   28.114 ? 291  TRP A CD2 1 
ATOM   2157 N  NE1 . TRP A 1 299 ? -19.138 2.349   54.071  1   30.06  ? 291  TRP A NE1 1 
ATOM   2158 C  CE2 . TRP A 1 299 ? -18.079 1.625   53.592  1   29.173 ? 291  TRP A CE2 1 
ATOM   2159 C  CE3 . TRP A 1 299 ? -17.492 -0.7    53.229  1   25.875 ? 291  TRP A CE3 1 
ATOM   2160 C  CZ2 . TRP A 1 299 ? -16.854 2.047   53.072  1   27.785 ? 291  TRP A CZ2 1 
ATOM   2161 C  CZ3 . TRP A 1 299 ? -16.265 -0.278  52.734  1   25.206 ? 291  TRP A CZ3 1 
ATOM   2162 C  CH2 . TRP A 1 299 ? -15.944 1.076   52.693  1   24.197 ? 291  TRP A CH2 1 
ATOM   2163 N  N   . ILE A 1 300 ? -21.991 -3.839  53.529  1   21.957 ? 292  ILE A N   1 
ATOM   2164 C  CA  . ILE A 1 300 ? -22.583 -5.087  54.004  1   23.931 ? 292  ILE A CA  1 
ATOM   2165 C  C   . ILE A 1 300 ? -21.529 -5.826  54.819  1   23.193 ? 292  ILE A C   1 
ATOM   2166 O  O   . ILE A 1 300 ? -20.523 -6.265  54.252  1   22.986 ? 292  ILE A O   1 
ATOM   2167 C  CB  . ILE A 1 300 ? -23.142 -5.92   52.831  1   22.382 ? 292  ILE A CB  1 
ATOM   2168 C  CG1 . ILE A 1 300 ? -24.178 -5.117  52.023  1   22.253 ? 292  ILE A CG1 1 
ATOM   2169 C  CG2 . ILE A 1 300 ? -23.686 -7.26   53.329  1   25.273 ? 292  ILE A CG2 1 
ATOM   2170 C  CD1 . ILE A 1 300 ? -24.722 -5.882  50.823  1   26.705 ? 292  ILE A CD1 1 
ATOM   2171 N  N   . THR A 1 301 ? -21.727 -5.945  56.148  1   21.119 ? 293  THR A N   1 
ATOM   2172 C  CA  . THR A 1 301 ? -20.824 -6.768  56.934  1   21.2   ? 293  THR A CA  1 
ATOM   2173 C  C   . THR A 1 301 ? -21.304 -8.228  56.898  1   23.27  ? 293  THR A C   1 
ATOM   2174 O  O   . THR A 1 301 ? -22.49  -8.521  57.155  1   23.663 ? 293  THR A O   1 
ATOM   2175 C  CB  . THR A 1 301 ? -20.691 -6.248  58.376  1   22.688 ? 293  THR A CB  1 
ATOM   2176 O  OG1 . THR A 1 301 ? -22.005 -6.072  58.922  1   21.705 ? 293  THR A OG1 1 
ATOM   2177 C  CG2 . THR A 1 301 ? -19.96  -4.913  58.425  1   21.471 ? 293  THR A CG2 1 
ATOM   2178 N  N   . ILE A 1 302 ? -20.375 -9.134  56.601  1   22.765 ? 294  ILE A N   1 
ATOM   2179 C  CA  . ILE A 1 302 ? -20.669 -10.564 56.573  1   23.175 ? 294  ILE A CA  1 
ATOM   2180 C  C   . ILE A 1 302 ? -19.721 -11.207 57.565  1   24.162 ? 294  ILE A C   1 
ATOM   2181 O  O   . ILE A 1 302 ? -18.522 -11.301 57.299  1   21.577 ? 294  ILE A O   1 
ATOM   2182 C  CB  . ILE A 1 302 ? -20.492 -11.188 55.173  1   23.431 ? 294  ILE A CB  1 
ATOM   2183 C  CG1 . ILE A 1 302 ? -21.341 -10.437 54.112  1   24.052 ? 294  ILE A CG1 1 
ATOM   2184 C  CG2 . ILE A 1 302 ? -20.812 -12.693 55.198  1   22.589 ? 294  ILE A CG2 1 
ATOM   2185 C  CD1 . ILE A 1 302 ? -21.023 -10.842 52.679  1   24.409 ? 294  ILE A CD1 1 
ATOM   2186 N  N   . PRO A 1 303 ? -20.224 -11.662 58.745  1   24.623 ? 295  PRO A N   1 
ATOM   2187 C  CA  . PRO A 1 303 ? -19.366 -12.424 59.649  1   23.517 ? 295  PRO A CA  1 
ATOM   2188 C  C   . PRO A 1 303 ? -18.78  -13.632 58.926  1   22.895 ? 295  PRO A C   1 
ATOM   2189 O  O   . PRO A 1 303 ? -19.505 -14.371 58.254  1   24.146 ? 295  PRO A O   1 
ATOM   2190 C  CB  . PRO A 1 303 ? -20.32  -12.838 60.79   1   26.979 ? 295  PRO A CB  1 
ATOM   2191 C  CG  . PRO A 1 303 ? -21.411 -11.77  60.727  1   26.198 ? 295  PRO A CG  1 
ATOM   2192 C  CD  . PRO A 1 303 ? -21.603 -11.49  59.234  1   26.61  ? 295  PRO A CD  1 
ATOM   2193 N  N   . ARG A 1 304 ? -17.453 -13.815 59.026  1   25.793 ? 296  ARG A N   1 
ATOM   2194 C  CA  . ARG A 1 304 ? -16.824 -14.919 58.31   1   24.636 ? 296  ARG A CA  1 
ATOM   2195 C  C   . ARG A 1 304 ? -17.333 -16.246 58.871  1   26.8   ? 296  ARG A C   1 
ATOM   2196 O  O   . ARG A 1 304 ? -17.422 -16.411 60.076  1   26.362 ? 296  ARG A O   1 
ATOM   2197 C  CB  . ARG A 1 304 ? -15.296 -14.807 58.349  1   24.262 ? 296  ARG A CB  1 
ATOM   2198 C  CG  . ARG A 1 304 ? -14.869 -13.573 57.558  1   24.089 ? 296  ARG A CG  1 
ATOM   2199 C  CD  . ARG A 1 304 ? -13.344 -13.352 57.617  1   22.945 ? 296  ARG A CD  1 
ATOM   2200 N  NE  . ARG A 1 304 ? -12.595 -14.466 56.999  1   21.687 ? 296  ARG A NE  1 
ATOM   2201 C  CZ  . ARG A 1 304 ? -11.277 -14.539 56.996  1   23.237 ? 296  ARG A CZ  1 
ATOM   2202 N  NH1 . ARG A 1 304 ? -10.552 -13.583 57.58   1   22.512 ? 296  ARG A NH1 1 
ATOM   2203 N  NH2 . ARG A 1 304 ? -10.681 -15.612 56.466  1   22.251 ? 296  ARG A NH2 1 
ATOM   2204 N  N   . GLY A 1 305 ? -17.662 -17.176 57.987  1   24.299 ? 297  GLY A N   1 
ATOM   2205 C  CA  . GLY A 1 305 ? -18.314 -18.438 58.335  1   25.898 ? 297  GLY A CA  1 
ATOM   2206 C  C   . GLY A 1 305 ? -19.742 -18.294 58.887  1   29.798 ? 297  GLY A C   1 
ATOM   2207 O  O   . GLY A 1 305 ? -20.244 -19.26  59.473  1   27.022 ? 297  GLY A O   1 
ATOM   2208 N  N   . ALA A 1 306 ? -20.438 -17.159 58.638  1   26.074 ? 298  ALA A N   1 
ATOM   2209 C  CA  . ALA A 1 306 ? -21.823 -16.98  59.069  1   25.992 ? 298  ALA A CA  1 
ATOM   2210 C  C   . ALA A 1 306 ? -22.7   -18.149 58.621  1   28.212 ? 298  ALA A C   1 
ATOM   2211 O  O   . ALA A 1 306 ? -22.545 -18.671 57.516  1   26.018 ? 298  ALA A O   1 
ATOM   2212 C  CB  . ALA A 1 306 ? -22.399 -15.692 58.499  1   29.426 ? 298  ALA A CB  1 
ATOM   2213 N  N   . LYS A 1 307 ? -23.619 -18.564 59.512  1   25.985 ? 299  LYS A N   1 
ATOM   2214 C  CA  . LYS A 1 307 ? -24.503 -19.697 59.23   1   28.215 ? 299  LYS A CA  1 
ATOM   2215 C  C   . LYS A 1 307 ? -25.859 -19.266 58.681  1   28.322 ? 299  LYS A C   1 
ATOM   2216 O  O   . LYS A 1 307 ? -26.611 -20.091 58.155  1   29.016 ? 299  LYS A O   1 
ATOM   2217 C  CB  . LYS A 1 307 ? -24.587 -20.604 60.467  1   30.871 ? 299  LYS A CB  1 
ATOM   2218 C  CG  . LYS A 1 307 ? -23.242 -21.236 60.835  1   25.647 ? 299  LYS A CG  1 
ATOM   2219 C  CD  . LYS A 1 307 ? -22.637 -22.084 59.732  1   28.047 ? 299  LYS A CD  1 
ATOM   2220 C  CE  . LYS A 1 307 ? -21.506 -23.022 60.123  1   31.66  ? 299  LYS A CE  1 
ATOM   2221 N  NZ  . LYS A 1 307 ? -20.38  -22.163 60.541  1   36.811 ? 299  LYS A NZ  1 
ATOM   2222 N  N   . SER A 1 308 ? -26.146 -17.969 58.763  1   26.752 ? 300  SER A N   1 
ATOM   2223 C  CA  . SER A 1 308 ? -27.437 -17.439 58.37   1   25.605 ? 300  SER A CA  1 
ATOM   2224 C  C   . SER A 1 308 ? -27.247 -16.018 57.835  1   23.447 ? 300  SER A C   1 
ATOM   2225 O  O   . SER A 1 308 ? -26.469 -15.269 58.4    1   25.937 ? 300  SER A O   1 
ATOM   2226 C  CB  . SER A 1 308 ? -28.395 -17.393 59.592  1   26.957 ? 300  SER A CB  1 
ATOM   2227 O  OG  . SER A 1 308 ? -29.593 -16.71  59.24   1   28.955 ? 300  SER A OG  1 
ATOM   2228 N  N   . LYS A 1 309 ? -28.051 -15.655 56.827  1   28.363 ? 301  LYS A N   1 
ATOM   2229 C  CA  . LYS A 1 309 ? -28.056 -14.29  56.318  1   27.947 ? 301  LYS A CA  1 
ATOM   2230 C  C   . LYS A 1 309 ? -28.605 -13.314 57.36   1   30.06  ? 301  LYS A C   1 
ATOM   2231 O  O   . LYS A 1 309 ? -28.416 -12.104 57.237  1   26.254 ? 301  LYS A O   1 
ATOM   2232 C  CB  . LYS A 1 309 ? -28.816 -14.208 54.996  1   31.316 ? 301  LYS A CB  1 
ATOM   2233 C  CG  . LYS A 1 309 ? -30.306 -14.357 55.11   1   30.912 ? 301  LYS A CG  1 
ATOM   2234 C  CD  . LYS A 1 309 ? -30.944 -14.295 53.73   1   33.684 ? 301  LYS A CD  1 
ATOM   2235 C  CE  . LYS A 1 309 ? -32.394 -14.362 54.021  1   37.893 ? 301  LYS A CE  1 
ATOM   2236 N  NZ  . LYS A 1 309 ? -33.045 -15.228 53.04   1   53.11  ? 301  LYS A NZ  1 
ATOM   2237 N  N   . ASP A 1 310 ? -29.215 -13.838 58.442  1   27.323 ? 302  ASP A N   1 
ATOM   2238 C  CA  . ASP A 1 310 ? -29.66  -12.964 59.523  1   30.103 ? 302  ASP A CA  1 
ATOM   2239 C  C   . ASP A 1 310 ? -28.493 -12.321 60.255  1   30.009 ? 302  ASP A C   1 
ATOM   2240 O  O   . ASP A 1 310 ? -28.697 -11.348 60.969  1   32.868 ? 302  ASP A O   1 
ATOM   2241 C  CB  . ASP A 1 310 ? -30.53  -13.698 60.53   1   34.428 ? 302  ASP A CB  1 
ATOM   2242 C  CG  . ASP A 1 310 ? -31.826 -14.27  59.98   1   39.907 ? 302  ASP A CG  1 
ATOM   2243 O  OD1 . ASP A 1 310 ? -32.231 -13.898 58.843  1   47.446 ? 302  ASP A OD1 1 
ATOM   2244 O  OD2 . ASP A 1 310 ? -32.399 -15.125 60.683  1   48.514 ? 302  ASP A OD2 1 
ATOM   2245 N  N   . GLU A 1 311 ? -27.278 -12.856 60.078  1   27.379 ? 303  GLU A N   1 
ATOM   2246 C  CA  . GLU A 1 311 ? -26.086 -12.333 60.745  1   26.061 ? 303  GLU A CA  1 
ATOM   2247 C  C   . GLU A 1 311 ? -25.485 -11.156 59.972  1   25.458 ? 303  GLU A C   1 
ATOM   2248 O  O   . GLU A 1 311 ? -24.679 -10.409 60.516  1   26.484 ? 303  GLU A O   1 
ATOM   2249 C  CB  . GLU A 1 311 ? -25.025 -13.43  60.817  1   25.854 ? 303  GLU A CB  1 
ATOM   2250 C  CG  . GLU A 1 311 ? -25.399 -14.586 61.747  1   28.715 ? 303  GLU A CG  1 
ATOM   2251 C  CD  . GLU A 1 311 ? -24.287 -15.63  61.79   1   30.141 ? 303  GLU A CD  1 
ATOM   2252 O  OE1 . GLU A 1 311 ? -23.104 -15.307 62.133  1   37.862 ? 303  GLU A OE1 1 
ATOM   2253 O  OE2 . GLU A 1 311 ? -24.607 -16.781 61.416  1   32.803 ? 303  GLU A OE2 1 
ATOM   2254 N  N   . VAL A 1 312 ? -25.919 -10.976 58.72   1   23.589 ? 304  VAL A N   1 
ATOM   2255 C  CA  . VAL A 1 312 ? -25.403 -9.918  57.847  1   23.622 ? 304  VAL A CA  1 
ATOM   2256 C  C   . VAL A 1 312 ? -26.087 -8.604  58.216  1   23.57  ? 304  VAL A C   1 
ATOM   2257 O  O   . VAL A 1 312 ? -27.315 -8.596  58.444  1   25.091 ? 304  VAL A O   1 
ATOM   2258 C  CB  . VAL A 1 312 ? -25.747 -10.343 56.395  1   22.071 ? 304  VAL A CB  1 
ATOM   2259 C  CG1 . VAL A 1 312 ? -25.55  -9.217  55.384  1   24.641 ? 304  VAL A CG1 1 
ATOM   2260 C  CG2 . VAL A 1 312 ? -24.945 -11.559 55.978  1   23.421 ? 304  VAL A CG2 1 
ATOM   2261 N  N   . LYS A 1 313 ? -25.322 -7.493  58.185  1   22.474 ? 305  LYS A N   1 
ATOM   2262 C  CA  . LYS A 1 313 ? -25.879 -6.172  58.453  1   24.017 ? 305  LYS A CA  1 
ATOM   2263 C  C   . LYS A 1 313 ? -25.534 -5.177  57.353  1   24.078 ? 305  LYS A C   1 
ATOM   2264 O  O   . LYS A 1 313 ? -24.465 -5.25   56.734  1   25.264 ? 305  LYS A O   1 
ATOM   2265 C  CB  . LYS A 1 313 ? -25.383 -5.64   59.805  1   23.926 ? 305  LYS A CB  1 
ATOM   2266 C  CG  . LYS A 1 313 ? -25.97  -6.477  60.977  1   27.736 ? 305  LYS A CG  1 
ATOM   2267 C  CD  . LYS A 1 313 ? -25.536 -5.961  62.335  1   37.31  ? 305  LYS A CD  1 
ATOM   2268 C  CE  . LYS A 1 313 ? -26.078 -6.738  63.518  1   42.872 ? 305  LYS A CE  1 
ATOM   2269 N  NZ  . LYS A 1 313 ? -27.493 -7.081  63.365  1   58.68  ? 305  LYS A NZ  1 
ATOM   2270 N  N   . TYR A 1 314 ? -26.482 -4.266  57.106  1   24.465 ? 306  TYR A N   1 
ATOM   2271 C  CA  . TYR A 1 314 ? -26.274 -3.151  56.177  1   25.352 ? 306  TYR A CA  1 
ATOM   2272 C  C   . TYR A 1 314 ? -25.971 -1.863  56.951  1   28.081 ? 306  TYR A C   1 
ATOM   2273 O  O   . TYR A 1 314 ? -26.68  -1.544  57.909  1   26.001 ? 306  TYR A O   1 
ATOM   2274 C  CB  . TYR A 1 314 ? -27.549 -2.887  55.369  1   23.034 ? 306  TYR A CB  1 
ATOM   2275 C  CG  . TYR A 1 314 ? -28.145 -4.039  54.589  1   24.11  ? 306  TYR A CG  1 
ATOM   2276 C  CD1 . TYR A 1 314 ? -27.351 -5.123  54.171  1   23.155 ? 306  TYR A CD1 1 
ATOM   2277 C  CD2 . TYR A 1 314 ? -29.477 -3.99   54.191  1   26.007 ? 306  TYR A CD2 1 
ATOM   2278 C  CE1 . TYR A 1 314 ? -27.891 -6.15   53.414  1   23.526 ? 306  TYR A CE1 1 
ATOM   2279 C  CE2 . TYR A 1 314 ? -30.023 -5.005  53.412  1   30.132 ? 306  TYR A CE2 1 
ATOM   2280 C  CZ  . TYR A 1 314 ? -29.228 -6.082  53.043  1   27.174 ? 306  TYR A CZ  1 
ATOM   2281 O  OH  . TYR A 1 314 ? -29.764 -7.061  52.27   1   29.001 ? 306  TYR A OH  1 
ATOM   2282 N  N   . TRP A 1 315 ? -24.925 -1.132  56.518  1   22.773 ? 307  TRP A N   1 
ATOM   2283 C  CA  . TRP A 1 315 ? -24.509 0.122   57.132  1   24.521 ? 307  TRP A CA  1 
ATOM   2284 C  C   . TRP A 1 315 ? -24.557 1.206   56.06   1   26.83  ? 307  TRP A C   1 
ATOM   2285 O  O   . TRP A 1 315 ? -24.281 0.913   54.904  1   24.842 ? 307  TRP A O   1 
ATOM   2286 C  CB  . TRP A 1 315 ? -23.102 -0.015  57.734  1   22.519 ? 307  TRP A CB  1 
ATOM   2287 C  CG  . TRP A 1 315 ? -22.963 -1.212  58.642  1   23.366 ? 307  TRP A CG  1 
ATOM   2288 C  CD1 . TRP A 1 315 ? -22.813 -2.517  58.266  1   26.801 ? 307  TRP A CD1 1 
ATOM   2289 C  CD2 . TRP A 1 315 ? -22.938 -1.212  60.089  1   22.81  ? 307  TRP A CD2 1 
ATOM   2290 N  NE1 . TRP A 1 315 ? -22.734 -3.338  59.368  1   24.723 ? 307  TRP A NE1 1 
ATOM   2291 C  CE2 . TRP A 1 315 ? -22.767 -2.557  60.499  1   25.188 ? 307  TRP A CE2 1 
ATOM   2292 C  CE3 . TRP A 1 315 ? -23.024 -0.206  61.058  1   24.725 ? 307  TRP A CE3 1 
ATOM   2293 C  CZ2 . TRP A 1 315 ? -22.732 -2.933  61.843  1   27.212 ? 307  TRP A CZ2 1 
ATOM   2294 C  CZ3 . TRP A 1 315 ? -22.958 -0.569  62.387  1   26.449 ? 307  TRP A CZ3 1 
ATOM   2295 C  CH2 . TRP A 1 315 ? -22.827 -1.913  62.766  1   28.785 ? 307  TRP A CH2 1 
ATOM   2296 N  N   . HIS A 1 316 ? -24.867 2.458   56.42   1   27.339 ? 308  HIS A N   1 
ATOM   2297 C  CA  . HIS A 1 316 ? -24.928 3.481   55.38   1   23.961 ? 308  HIS A CA  1 
ATOM   2298 C  C   . HIS A 1 316 ? -24.232 4.753   55.824  1   25.257 ? 308  HIS A C   1 
ATOM   2299 O  O   . HIS A 1 316 ? -24.189 5.062   57.016  1   23.612 ? 308  HIS A O   1 
ATOM   2300 C  CB  . HIS A 1 316 ? -26.358 3.825   54.94   1   26.034 ? 308  HIS A CB  1 
ATOM   2301 C  CG  . HIS A 1 316 ? -27.192 4.419   56.022  1   28.685 ? 308  HIS A CG  1 
ATOM   2302 N  ND1 . HIS A 1 316 ? -27.697 3.708   57.095  1   30.578 ? 308  HIS A ND1 1 
ATOM   2303 C  CD2 . HIS A 1 316 ? -27.581 5.69    56.188  1   35.36  ? 308  HIS A CD2 1 
ATOM   2304 C  CE1 . HIS A 1 316 ? -28.377 4.533   57.89   1   31.127 ? 308  HIS A CE1 1 
ATOM   2305 N  NE2 . HIS A 1 316 ? -28.329 5.735   57.354  1   31.417 ? 308  HIS A NE2 1 
ATOM   2306 N  N   . TRP A 1 317 ? -23.718 5.491   54.828  1   22.411 ? 309  TRP A N   1 
ATOM   2307 C  CA  . TRP A 1 317 ? -23.254 6.843   55.078  1   23.448 ? 309  TRP A CA  1 
ATOM   2308 C  C   . TRP A 1 317 ? -24.066 7.825   54.233  1   24.626 ? 309  TRP A C   1 
ATOM   2309 O  O   . TRP A 1 317 ? -25.262 8.01    54.467  1   26.361 ? 309  TRP A O   1 
ATOM   2310 C  CB  . TRP A 1 317 ? -21.73  6.922   54.933  1   23.214 ? 309  TRP A CB  1 
ATOM   2311 C  CG  . TRP A 1 317 ? -21.218 8.297   55.276  1   23.897 ? 309  TRP A CG  1 
ATOM   2312 C  CD1 . TRP A 1 317 ? -21.359 8.985   56.458  1   28.184 ? 309  TRP A CD1 1 
ATOM   2313 C  CD2 . TRP A 1 317 ? -20.587 9.193   54.345  1   27.015 ? 309  TRP A CD2 1 
ATOM   2314 N  NE1 . TRP A 1 317 ? -20.785 10.23   56.351  1   27.445 ? 309  TRP A NE1 1 
ATOM   2315 C  CE2 . TRP A 1 317 ? -20.319 10.393  55.065  1   27.616 ? 309  TRP A CE2 1 
ATOM   2316 C  CE3 . TRP A 1 317 ? -20.198 9.076   52.991  1   26.47  ? 309  TRP A CE3 1 
ATOM   2317 C  CZ2 . TRP A 1 317 ? -19.664 11.474  54.46   1   26.789 ? 309  TRP A CZ2 1 
ATOM   2318 C  CZ3 . TRP A 1 317 ? -19.571 10.151  52.39   1   26.849 ? 309  TRP A CZ3 1 
ATOM   2319 C  CH2 . TRP A 1 317 ? -19.294 11.322  53.127  1   31.81  ? 309  TRP A CH2 1 
ATOM   2320 N  N   . LYS A 1 318 ? -23.458 8.378   53.184  1   24.375 ? 310  LYS A N   1 
ATOM   2321 C  CA  . LYS A 1 318 ? -24.069 9.39    52.332  1   23.684 ? 310  LYS A CA  1 
ATOM   2322 C  C   . LYS A 1 318 ? -23.596 9.108   50.915  1   27.069 ? 310  LYS A C   1 
ATOM   2323 O  O   . LYS A 1 318 ? -22.736 8.252   50.752  1   23.596 ? 310  LYS A O   1 
ATOM   2324 C  CB  . LYS A 1 318 ? -23.579 10.784  52.761  1   24.238 ? 310  LYS A CB  1 
ATOM   2325 C  CG  . LYS A 1 318 ? -23.991 11.189  54.188  1   26.862 ? 310  LYS A CG  1 
ATOM   2326 C  CD  . LYS A 1 318 ? -23.408 12.513  54.703  1   29.248 ? 310  LYS A CD  1 
ATOM   2327 C  CE  . LYS A 1 318 ? -24.093 12.806  56.044  1   34.758 ? 310  LYS A CE  1 
ATOM   2328 N  NZ  . LYS A 1 318 ? -23.426 13.893  56.772  1   37.805 ? 310  LYS A NZ  1 
ATOM   2329 N  N   . ASN A 1 319 ? -24.095 9.871   49.939  1   23.012 ? 311  ASN A N   1 
ATOM   2330 C  CA  . ASN A 1 319 ? -23.723 9.63    48.55   1   24.35  ? 311  ASN A CA  1 
ATOM   2331 C  C   . ASN A 1 319 ? -22.255 9.946   48.281  1   25.474 ? 311  ASN A C   1 
ATOM   2332 O  O   . ASN A 1 319 ? -21.727 10.96   48.718  1   25.393 ? 311  ASN A O   1 
ATOM   2333 C  CB  . ASN A 1 319 ? -24.59  10.443  47.605  1   27.79  ? 311  ASN A CB  1 
ATOM   2334 C  CG  . ASN A 1 319 ? -24.33  10.078  46.161  1   27.352 ? 311  ASN A CG  1 
ATOM   2335 O  OD1 . ASN A 1 319 ? -23.734 10.877  45.432  1   25.623 ? 311  ASN A OD1 1 
ATOM   2336 N  ND2 . ASN A 1 319 ? -24.78  8.901   45.737  1   24.632 ? 311  ASN A ND2 1 
ATOM   2337 N  N   . GLY A 1 320 ? -21.638 9.13    47.427  1   22.482 ? 312  GLY A N   1 
ATOM   2338 C  CA  . GLY A 1 320 ? -20.289 9.326   46.917  1   24.314 ? 312  GLY A CA  1 
ATOM   2339 C  C   . GLY A 1 320 ? -19.813 8       46.316  1   23.697 ? 312  GLY A C   1 
ATOM   2340 O  O   . GLY A 1 320 ? -20.549 7.011   46.38   1   23.58  ? 312  GLY A O   1 
ATOM   2341 N  N   . MET A 1 321 ? -18.564 7.968   45.808  1   21.357 ? 313  MET A N   1 
ATOM   2342 C  CA  . MET A 1 321 ? -18.072 6.788   45.113  1   20.87  ? 313  MET A CA  1 
ATOM   2343 C  C   . MET A 1 321 ? -16.722 6.433   45.737  1   21.486 ? 313  MET A C   1 
ATOM   2344 O  O   . MET A 1 321 ? -15.665 6.975   45.355  1   24.194 ? 313  MET A O   1 
ATOM   2345 C  CB  . MET A 1 321 ? -18.031 7.053   43.595  1   21.184 ? 313  MET A CB  1 
ATOM   2346 C  CG  . MET A 1 321 ? -17.601 5.854   42.781  1   21.66  ? 313  MET A CG  1 
ATOM   2347 S  SD  . MET A 1 321 ? -18.093 6.183   41.077  1   23.958 ? 313  MET A SD  1 
ATOM   2348 C  CE  . MET A 1 321 ? -17.206 4.78    40.337  1   19.925 ? 313  MET A CE  1 
ATOM   2349 N  N   . PRO A 1 322 ? -16.71  5.503   46.713  1   21.636 ? 314  PRO A N   1 
ATOM   2350 C  CA  . PRO A 1 322 ? -15.457 4.971   47.22   1   21.103 ? 314  PRO A CA  1 
ATOM   2351 C  C   . PRO A 1 322 ? -15.02  3.81    46.326  1   21.571 ? 314  PRO A C   1 
ATOM   2352 O  O   . PRO A 1 322 ? -15.68  2.763   46.343  1   22.855 ? 314  PRO A O   1 
ATOM   2353 C  CB  . PRO A 1 322 ? -15.842 4.602   48.648  1   20.729 ? 314  PRO A CB  1 
ATOM   2354 C  CG  . PRO A 1 322 ? -17.311 4.133   48.534  1   20.864 ? 314  PRO A CG  1 
ATOM   2355 C  CD  . PRO A 1 322 ? -17.882 4.798   47.281  1   23.144 ? 314  PRO A CD  1 
ATOM   2356 N  N   . ILE A 1 323 ? -13.96  4.013   45.526  1   23.011 ? 315  ILE A N   1 
ATOM   2357 C  CA  . ILE A 1 323 ? -13.77  3.11    44.387  1   21.03  ? 315  ILE A CA  1 
ATOM   2358 C  C   . ILE A 1 323 ? -13.094 1.819   44.84   1   18.755 ? 315  ILE A C   1 
ATOM   2359 O  O   . ILE A 1 323 ? -13.585 0.754   44.497  1   21.828 ? 315  ILE A O   1 
ATOM   2360 C  CB  . ILE A 1 323 ? -13.027 3.816   43.238  1   21.117 ? 315  ILE A CB  1 
ATOM   2361 C  CG1 . ILE A 1 323 ? -13.784 5.062   42.801  1   22.319 ? 315  ILE A CG1 1 
ATOM   2362 C  CG2 . ILE A 1 323 ? -12.771 2.859   42.054  1   18.034 ? 315  ILE A CG2 1 
ATOM   2363 C  CD1 . ILE A 1 323 ? -12.893 5.984   41.963  1   25.603 ? 315  ILE A CD1 1 
ATOM   2364 N  N   . HIS A 1 324 ? -11.998 1.94    45.598  1   19.113 ? 316  HIS A N   1 
ATOM   2365 C  CA  . HIS A 1 324 ? -11.19  0.806   46.016  1   19.138 ? 316  HIS A CA  1 
ATOM   2366 C  C   . HIS A 1 324 ? -10.814 0.954   47.475  1   21.94  ? 316  HIS A C   1 
ATOM   2367 O  O   . HIS A 1 324 ? -10.503 2.047   47.927  1   23.048 ? 316  HIS A O   1 
ATOM   2368 C  CB  . HIS A 1 324 ? -9.885  0.745   45.216  1   20.153 ? 316  HIS A CB  1 
ATOM   2369 C  CG  . HIS A 1 324 ? -10.115 0.223   43.833  1   19.177 ? 316  HIS A CG  1 
ATOM   2370 N  ND1 . HIS A 1 324 ? -9.842  0.995   42.73   1   21.203 ? 316  HIS A ND1 1 
ATOM   2371 C  CD2 . HIS A 1 324 ? -10.563 -0.947  43.368  1   20.81  ? 316  HIS A CD2 1 
ATOM   2372 C  CE1 . HIS A 1 324 ? -10.103 0.308   41.625  1   21.791 ? 316  HIS A CE1 1 
ATOM   2373 N  NE2 . HIS A 1 324 ? -10.567 -0.857  41.989  1   22.944 ? 316  HIS A NE2 1 
ATOM   2374 N  N   . THR A 1 325 ? -10.747 -0.194  48.138  1   21.006 ? 317  THR A N   1 
ATOM   2375 C  CA  . THR A 1 325 ? -10.209 -0.229  49.484  1   21.47  ? 317  THR A CA  1 
ATOM   2376 C  C   . THR A 1 325 ? -8.701  -0.464  49.41   1   21.417 ? 317  THR A C   1 
ATOM   2377 O  O   . THR A 1 325 ? -8.206  -1.125  48.491  1   19.338 ? 317  THR A O   1 
ATOM   2378 C  CB  . THR A 1 325 ? -10.912 -1.274  50.326  1   20.749 ? 317  THR A CB  1 
ATOM   2379 O  OG1 . THR A 1 325 ? -10.611 -2.552  49.768  1   22.543 ? 317  THR A OG1 1 
ATOM   2380 C  CG2 . THR A 1 325 ? -12.405 -1.028  50.489  1   19.645 ? 317  THR A CG2 1 
ATOM   2381 N  N   . ALA A 1 326 ? -7.963  0.116   50.38   1   22.274 ? 318  ALA A N   1 
ATOM   2382 C  CA  . ALA A 1 326 ? -6.591  -0.288  50.613  1   22.224 ? 318  ALA A CA  1 
ATOM   2383 C  C   . ALA A 1 326 ? -6.642  -1.659  51.289  1   25.474 ? 318  ALA A C   1 
ATOM   2384 O  O   . ALA A 1 326 ? -6.488  -2.701  50.656  1   20.644 ? 318  ALA A O   1 
ATOM   2385 C  CB  . ALA A 1 326 ? -5.843  0.792   51.42   1   23.433 ? 318  ALA A CB  1 
ATOM   2386 N  N   . SER A 1 327 ? -6.975  -1.674  52.587  1   22.87  ? 319  SER A N   1 
ATOM   2387 C  CA  . SER A 1 327 ? -7.452  -2.913  53.189  1   22.445 ? 319  SER A CA  1 
ATOM   2388 C  C   . SER A 1 327 ? -8.322  -2.545  54.396  1   25.103 ? 319  SER A C   1 
ATOM   2389 O  O   . SER A 1 327 ? -8.747  -1.381  54.523  1   22.875 ? 319  SER A O   1 
ATOM   2390 C  CB  . SER A 1 327 ? -6.303  -3.911  53.511  1   21.549 ? 319  SER A CB  1 
ATOM   2391 O  OG  . SER A 1 327 ? -6.846  -5.212  53.793  1   21.998 ? 319  SER A OG  1 
ATOM   2392 N  N   . GLY A 1 328 ? -8.673  -3.569  55.18   1   21.623 ? 320  GLY A N   1 
ATOM   2393 C  CA  . GLY A 1 328 ? -9.348  -3.345  56.443  1   23.059 ? 320  GLY A CA  1 
ATOM   2394 C  C   . GLY A 1 328 ? -8.692  -4.109  57.583  1   23.675 ? 320  GLY A C   1 
ATOM   2395 O  O   . GLY A 1 328 ? -7.823  -4.952  57.363  1   25.664 ? 320  GLY A O   1 
ATOM   2396 N  N   . PHE A 1 329 ? -9.13   -3.79   58.806  1   24.118 ? 321  PHE A N   1 
ATOM   2397 C  CA  . PHE A 1 329 ? -8.748  -4.594  59.964  1   22.919 ? 321  PHE A CA  1 
ATOM   2398 C  C   . PHE A 1 329 ? -9.719  -4.295  61.093  1   24.235 ? 321  PHE A C   1 
ATOM   2399 O  O   . PHE A 1 329 ? -10.564 -3.427  60.949  1   25.471 ? 321  PHE A O   1 
ATOM   2400 C  CB  . PHE A 1 329 ? -7.287  -4.356  60.381  1   21.528 ? 321  PHE A CB  1 
ATOM   2401 C  CG  . PHE A 1 329 ? -6.98   -2.948  60.873  1   24.322 ? 321  PHE A CG  1 
ATOM   2402 C  CD1 . PHE A 1 329 ? -6.714  -1.901  59.982  1   28.497 ? 321  PHE A CD1 1 
ATOM   2403 C  CD2 . PHE A 1 329 ? -6.962  -2.669  62.257  1   23.914 ? 321  PHE A CD2 1 
ATOM   2404 C  CE1 . PHE A 1 329 ? -6.474  -0.613  60.447  1   28.334 ? 321  PHE A CE1 1 
ATOM   2405 C  CE2 . PHE A 1 329 ? -6.684  -1.392  62.717  1   26.287 ? 321  PHE A CE2 1 
ATOM   2406 C  CZ  . PHE A 1 329 ? -6.457  -0.364  61.826  1   30.16  ? 321  PHE A CZ  1 
ATOM   2407 N  N   . GLU A 1 330 ? -9.59   -5.062  62.192  1   25.337 ? 322  GLU A N   1 
ATOM   2408 C  CA  . GLU A 1 330 ? -10.343 -4.773  63.401  1   26.638 ? 322  GLU A CA  1 
ATOM   2409 C  C   . GLU A 1 330 ? -9.372  -4.176  64.407  1   25.342 ? 322  GLU A C   1 
ATOM   2410 O  O   . GLU A 1 330 ? -8.315  -4.767  64.664  1   29.247 ? 322  GLU A O   1 
ATOM   2411 C  CB  . GLU A 1 330 ? -11.116 -6.003  63.893  1   27.175 ? 322  GLU A CB  1 
ATOM   2412 C  CG  . GLU A 1 330 ? -12.344 -6.299  63.021  1   26.629 ? 322  GLU A CG  1 
ATOM   2413 C  CD  . GLU A 1 330 ? -12.763 -7.754  63.15   1   31.992 ? 322  GLU A CD  1 
ATOM   2414 O  OE1 . GLU A 1 330 ? -13.033 -8.163  64.31   1   31.081 ? 322  GLU A OE1 1 
ATOM   2415 O  OE2 . GLU A 1 330 ? -12.762 -8.508  62.148  1   28.774 ? 322  GLU A OE2 1 
ATOM   2416 N  N   . ASP A 1 331 ? -9.739  -3.015  64.939  1   25.748 ? 323  ASP A N   1 
ATOM   2417 C  CA  . ASP A 1 331 ? -8.908  -2.365  65.943  1   30.017 ? 323  ASP A CA  1 
ATOM   2418 C  C   . ASP A 1 331 ? -9.015  -3.141  67.258  1   31.764 ? 323  ASP A C   1 
ATOM   2419 O  O   . ASP A 1 331 ? -9.695  -4.174  67.335  1   27.494 ? 323  ASP A O   1 
ATOM   2420 C  CB  . ASP A 1 331 ? -9.218  -0.881  66.062  1   27.796 ? 323  ASP A CB  1 
ATOM   2421 C  CG  . ASP A 1 331 ? -10.534 -0.514  66.747  1   28.364 ? 323  ASP A CG  1 
ATOM   2422 O  OD1 . ASP A 1 331 ? -11.205 -1.413  67.319  1   29.864 ? 323  ASP A OD1 1 
ATOM   2423 O  OD2 . ASP A 1 331 ? -10.926 0.682   66.65   1   29.967 ? 323  ASP A OD2 1 
ATOM   2424 N  N   . GLU A 1 332 ? -8.329  -2.636  68.3    1   32.738 ? 324  GLU A N   1 
ATOM   2425 C  CA  . GLU A 1 332 ? -8.235  -3.344  69.578  1   36.475 ? 324  GLU A CA  1 
ATOM   2426 C  C   . GLU A 1 332 ? -9.611  -3.57   70.215  1   31.136 ? 324  GLU A C   1 
ATOM   2427 O  O   . GLU A 1 332 ? -9.774  -4.552  70.949  1   34.114 ? 324  GLU A O   1 
ATOM   2428 C  CB  . GLU A 1 332 ? -7.279  -2.634  70.546  1   36.064 ? 324  GLU A CB  1 
ATOM   2429 C  CG  . GLU A 1 332 ? -7.692  -1.23   70.998  1   51.843 ? 324  GLU A CG  1 
ATOM   2430 C  CD  . GLU A 1 332 ? -7.738  -0.038  70.051  1   70.073 ? 324  GLU A CD  1 
ATOM   2431 O  OE1 . GLU A 1 332 ? -7.178  -0.089  68.924  1   73.181 ? 324  GLU A OE1 1 
ATOM   2432 O  OE2 . GLU A 1 332 ? -8.402  0.94    70.448  1   72.587 ? 324  GLU A OE2 1 
ATOM   2433 N  N   . GLN A 1 333 ? -10.565 -2.658  69.942  1   34.91  ? 325  GLN A N   1 
ATOM   2434 C  CA  . GLN A 1 333 ? -11.919 -2.663  70.474  1   35.797 ? 325  GLN A CA  1 
ATOM   2435 C  C   . GLN A 1 333 ? -12.913 -3.288  69.483  1   36.834 ? 325  GLN A C   1 
ATOM   2436 O  O   . GLN A 1 333 ? -14.13  -3.138  69.668  1   28.964 ? 325  GLN A O   1 
ATOM   2437 C  CB  . GLN A 1 333 ? -12.447 -1.229  70.592  1   40.102 ? 325  GLN A CB  1 
ATOM   2438 C  CG  . GLN A 1 333 ? -11.654 -0.296  71.496  1   53.419 ? 325  GLN A CG  1 
ATOM   2439 C  CD  . GLN A 1 333 ? -12.309 1.063   71.609  1   61.595 ? 325  GLN A CD  1 
ATOM   2440 O  OE1 . GLN A 1 333 ? -12.506 1.776   70.621  1   61.034 ? 325  GLN A OE1 1 
ATOM   2441 N  NE2 . GLN A 1 333 ? -12.675 1.428   72.827  1   75.636 ? 325  GLN A NE2 1 
ATOM   2442 N  N   . GLY A 1 334 ? -12.402 -3.939  68.421  1   33.462 ? 326  GLY A N   1 
ATOM   2443 C  CA  . GLY A 1 334 ? -13.245 -4.738  67.531  1   30.556 ? 326  GLY A CA  1 
ATOM   2444 C  C   . GLY A 1 334 ? -13.913 -3.907  66.428  1   30.633 ? 326  GLY A C   1 
ATOM   2445 O  O   . GLY A 1 334 ? -14.749 -4.425  65.69   1   30.878 ? 326  GLY A O   1 
ATOM   2446 N  N   . ARG A 1 335 ? -13.546 -2.622  66.312  1   26.198 ? 327  ARG A N   1 
ATOM   2447 C  CA  . ARG A 1 335 ? -14.156 -1.804  65.275  1   29.377 ? 327  ARG A CA  1 
ATOM   2448 C  C   . ARG A 1 335 ? -13.479 -2.127  63.936  1   26.876 ? 327  ARG A C   1 
ATOM   2449 O  O   . ARG A 1 335 ? -12.265 -2.328  63.902  1   24.512 ? 327  ARG A O   1 
ATOM   2450 C  CB  . ARG A 1 335 ? -14.06  -0.306  65.561  1   28.422 ? 327  ARG A CB  1 
ATOM   2451 C  CG  . ARG A 1 335 ? -14.572 0.002   66.97   1   33.207 ? 327  ARG A CG  1 
ATOM   2452 C  CD  . ARG A 1 335 ? -14.6   1.488   67.244  1   32.455 ? 327  ARG A CD  1 
ATOM   2453 N  NE  . ARG A 1 335 ? -13.265 2.079   67.345  1   46.725 ? 327  ARG A NE  1 
ATOM   2454 C  CZ  . ARG A 1 335 ? -13.052 3.361   67.606  1   56.107 ? 327  ARG A CZ  1 
ATOM   2455 N  NH1 . ARG A 1 335 ? -14.039 4.242   67.487  1   51.135 ? 327  ARG A NH1 1 
ATOM   2456 N  NH2 . ARG A 1 335 ? -11.833 3.748   67.952  1   51.233 ? 327  ARG A NH2 1 
ATOM   2457 N  N   . ILE A 1 336 ? -14.293 -2.149  62.88   1   26.848 ? 328  ILE A N   1 
ATOM   2458 C  CA  . ILE A 1 336 ? -13.828 -2.379  61.505  1   24.674 ? 328  ILE A CA  1 
ATOM   2459 C  C   . ILE A 1 336 ? -13.325 -1.037  60.977  1   23.926 ? 328  ILE A C   1 
ATOM   2460 O  O   . ILE A 1 336 ? -14.072 -0.053  60.975  1   25.176 ? 328  ILE A O   1 
ATOM   2461 C  CB  . ILE A 1 336 ? -14.977 -2.937  60.625  1   26.606 ? 328  ILE A CB  1 
ATOM   2462 C  CG1 . ILE A 1 336 ? -15.397 -4.326  61.073  1   24.904 ? 328  ILE A CG1 1 
ATOM   2463 C  CG2 . ILE A 1 336 ? -14.616 -2.922  59.117  1   25.07  ? 328  ILE A CG2 1 
ATOM   2464 C  CD1 . ILE A 1 336 ? -16.83  -4.667  60.697  1   22.899 ? 328  ILE A CD1 1 
ATOM   2465 N  N   . ILE A 1 337 ? -12.059 -1.03   60.54   1   23.102 ? 329  ILE A N   1 
ATOM   2466 C  CA  . ILE A 1 337 ? -11.395 0.171   60.042  1   22.051 ? 329  ILE A CA  1 
ATOM   2467 C  C   . ILE A 1 337 ? -11.055 -0.149  58.588  1   24.107 ? 329  ILE A C   1 
ATOM   2468 O  O   . ILE A 1 337 ? -10.353 -1.125  58.355  1   24.121 ? 329  ILE A O   1 
ATOM   2469 C  CB  . ILE A 1 337 ? -10.092 0.46    60.825  1   23.128 ? 329  ILE A CB  1 
ATOM   2470 C  CG1 . ILE A 1 337 ? -10.353 0.58    62.363  1   24.457 ? 329  ILE A CG1 1 
ATOM   2471 C  CG2 . ILE A 1 337 ? -9.401  1.706   60.27   1   24.751 ? 329  ILE A CG2 1 
ATOM   2472 C  CD1 . ILE A 1 337 ? -11.432 1.608   62.708  1   27.127 ? 329  ILE A CD1 1 
ATOM   2473 N  N   . ILE A 1 338 ? -11.496 0.696   57.656  1   23.875 ? 330  ILE A N   1 
ATOM   2474 C  CA  . ILE A 1 338 ? -11.224 0.435   56.232  1   22.587 ? 330  ILE A CA  1 
ATOM   2475 C  C   . ILE A 1 338 ? -10.805 1.761   55.608  1   21.675 ? 330  ILE A C   1 
ATOM   2476 O  O   . ILE A 1 338 ? -11.515 2.765   55.753  1   25.567 ? 330  ILE A O   1 
ATOM   2477 C  CB  . ILE A 1 338 ? -12.492 -0.096  55.544  1   23.123 ? 330  ILE A CB  1 
ATOM   2478 C  CG1 . ILE A 1 338 ? -13.014 -1.418  56.143  1   22.754 ? 330  ILE A CG1 1 
ATOM   2479 C  CG2 . ILE A 1 338 ? -12.274 -0.201  54.005  1   24.34  ? 330  ILE A CG2 1 
ATOM   2480 C  CD1 . ILE A 1 338 ? -14.471 -1.711  55.757  1   21.054 ? 330  ILE A CD1 1 
ATOM   2481 N  N   . ASP A 1 339 ? -9.692  1.744   54.851  1   20.872 ? 331  ASP A N   1 
ATOM   2482 C  CA  . ASP A 1 339 ? -9.327  2.947   54.124  1   21.55  ? 331  ASP A CA  1 
ATOM   2483 C  C   . ASP A 1 339 ? -9.687  2.743   52.649  1   21.237 ? 331  ASP A C   1 
ATOM   2484 O  O   . ASP A 1 339 ? -9.577  1.632   52.16   1   22.571 ? 331  ASP A O   1 
ATOM   2485 C  CB  . ASP A 1 339 ? -7.849  3.283   54.222  1   23.371 ? 331  ASP A CB  1 
ATOM   2486 C  CG  . ASP A 1 339 ? -7.338  3.709   55.603  1   30.059 ? 331  ASP A CG  1 
ATOM   2487 O  OD1 . ASP A 1 339 ? -8.128  3.575   56.597  1   28.084 ? 331  ASP A OD1 1 
ATOM   2488 O  OD2 . ASP A 1 339 ? -6.15   4.147   55.679  1   27.813 ? 331  ASP A OD2 1 
ATOM   2489 N  N   . SER A 1 340 ? -10.187 3.802   52.033  1   22.604 ? 332  SER A N   1 
ATOM   2490 C  CA  . SER A 1 340 ? -10.577 3.729   50.632  1   25.656 ? 332  SER A CA  1 
ATOM   2491 C  C   . SER A 1 340 ? -10.339 5.053   49.933  1   24.104 ? 332  SER A C   1 
ATOM   2492 O  O   . SER A 1 340 ? -10.219 6.088   50.575  1   24.439 ? 332  SER A O   1 
ATOM   2493 C  CB  . SER A 1 340 ? -12.035 3.303   50.474  1   22.638 ? 332  SER A CB  1 
ATOM   2494 O  OG  . SER A 1 340 ? -12.92  4.404   50.682  1   25.156 ? 332  SER A OG  1 
ATOM   2495 N  N   . SER A 1 341 ? -10.325 5.01    48.592  1   23.083 ? 333  SER A N   1 
ATOM   2496 C  CA  . SER A 1 341 ? -10.527 6.258   47.867  1   22.894 ? 333  SER A CA  1 
ATOM   2497 C  C   . SER A 1 341 ? -11.955 6.742   48.084  1   24.327 ? 333  SER A C   1 
ATOM   2498 O  O   . SER A 1 341 ? -12.836 5.963   48.468  1   24.627 ? 333  SER A O   1 
ATOM   2499 C  CB  . SER A 1 341 ? -10.223 6.09    46.381  1   24.774 ? 333  SER A CB  1 
ATOM   2500 O  OG  . SER A 1 341 ? -11.024 5.085   45.8    1   25.05  ? 333  SER A OG  1 
ATOM   2501 N  N   . LEU A 1 342 ? -12.176 8.05    47.893  1   22.508 ? 334  LEU A N   1 
ATOM   2502 C  CA  . LEU A 1 342 ? -13.535 8.575   47.987  1   19.513 ? 334  LEU A CA  1 
ATOM   2503 C  C   . LEU A 1 342 ? -13.644 9.699   46.99   1   22.28  ? 334  LEU A C   1 
ATOM   2504 O  O   . LEU A 1 342 ? -12.944 10.719  47.11   1   23.356 ? 334  LEU A O   1 
ATOM   2505 C  CB  . LEU A 1 342 ? -13.944 9.051   49.397  1   19.31  ? 334  LEU A CB  1 
ATOM   2506 C  CG  . LEU A 1 342 ? -15.329 9.7     49.505  1   21.393 ? 334  LEU A CG  1 
ATOM   2507 C  CD1 . LEU A 1 342 ? -16.548 8.847   49.035  1   23.297 ? 334  LEU A CD1 1 
ATOM   2508 C  CD2 . LEU A 1 342 ? -15.528 10.138  50.958  1   22.081 ? 334  LEU A CD2 1 
ATOM   2509 N  N   . VAL A 1 343 ? -14.526 9.47    46.007  1   24.503 ? 335  VAL A N   1 
ATOM   2510 C  CA  . VAL A 1 343 ? -14.807 10.477  45.009  1   22.273 ? 335  VAL A CA  1 
ATOM   2511 C  C   . VAL A 1 343 ? -16.195 11.013  45.316  1   26.189 ? 335  VAL A C   1 
ATOM   2512 O  O   . VAL A 1 343 ? -17.152 10.24   45.457  1   22.771 ? 335  VAL A O   1 
ATOM   2513 C  CB  . VAL A 1 343 ? -14.666 9.945   43.57   1   23.382 ? 335  VAL A CB  1 
ATOM   2514 C  CG1 . VAL A 1 343 ? -15.091 11.012  42.557  1   22.384 ? 335  VAL A CG1 1 
ATOM   2515 C  CG2 . VAL A 1 343 ? -13.227 9.455   43.296  1   23.52  ? 335  VAL A CG2 1 
ATOM   2516 N  N   . HIS A 1 344 ? -16.279 12.353  45.43   1   25.978 ? 336  HIS A N   1 
ATOM   2517 C  CA  . HIS A 1 344 ? -17.499 13.009  45.885  1   23.881 ? 336  HIS A CA  1 
ATOM   2518 C  C   . HIS A 1 344 ? -18.43  13.265  44.699  1   27.661 ? 336  HIS A C   1 
ATOM   2519 O  O   . HIS A 1 344 ? -18.824 14.393  44.42   1   25.611 ? 336  HIS A O   1 
ATOM   2520 C  CB  . HIS A 1 344 ? -17.131 14.285  46.653  1   24.97  ? 336  HIS A CB  1 
ATOM   2521 C  CG  . HIS A 1 344 ? -16.425 13.972  47.936  1   24.363 ? 336  HIS A CG  1 
ATOM   2522 N  ND1 . HIS A 1 344 ? -17.106 13.652  49.088  1   28.633 ? 336  HIS A ND1 1 
ATOM   2523 C  CD2 . HIS A 1 344 ? -15.125 13.898  48.236  1   26.327 ? 336  HIS A CD2 1 
ATOM   2524 C  CE1 . HIS A 1 344 ? -16.237 13.476  50.079  1   27.882 ? 336  HIS A CE1 1 
ATOM   2525 N  NE2 . HIS A 1 344 ? -15.023 13.564  49.571  1   30.952 ? 336  HIS A NE2 1 
ATOM   2526 N  N   . GLY A 1 345 ? -18.826 12.189  44.015  1   25.073 ? 337  GLY A N   1 
ATOM   2527 C  CA  . GLY A 1 345 ? -19.554 12.306  42.763  1   24.583 ? 337  GLY A CA  1 
ATOM   2528 C  C   . GLY A 1 345 ? -19.208 11.092  41.906  1   26.137 ? 337  GLY A C   1 
ATOM   2529 O  O   . GLY A 1 345 ? -18.62  10.121  42.395  1   22.401 ? 337  GLY A O   1 
ATOM   2530 N  N   . ASN A 1 346 ? -19.589 11.174  40.635  1   25.155 ? 338  ASN A N   1 
ATOM   2531 C  CA  . ASN A 1 346 ? -19.56  10.017  39.748  1   26.258 ? 338  ASN A CA  1 
ATOM   2532 C  C   . ASN A 1 346 ? -18.222 9.959   39.002  1   22.815 ? 338  ASN A C   1 
ATOM   2533 O  O   . ASN A 1 346 ? -18.007 10.725  38.059  1   24.783 ? 338  ASN A O   1 
ATOM   2534 C  CB  . ASN A 1 346 ? -20.785 9.995   38.838  1   24.27  ? 338  ASN A CB  1 
ATOM   2535 C  CG  . ASN A 1 346 ? -20.839 8.766   37.958  1   24.072 ? 338  ASN A CG  1 
ATOM   2536 O  OD1 . ASN A 1 346 ? -20.05  7.825   38.136  1   20.539 ? 338  ASN A OD1 1 
ATOM   2537 N  ND2 . ASN A 1 346 ? -21.764 8.741   37.005  1   21.107 ? 338  ASN A ND2 1 
ATOM   2538 N  N   . ALA A 1 347 ? -17.356 9.002   39.398  1   21.535 ? 339  ALA A N   1 
ATOM   2539 C  CA  . ALA A 1 347 ? -16.064 8.787   38.75   1   20.123 ? 339  ALA A CA  1 
ATOM   2540 C  C   . ALA A 1 347 ? -16.211 8.041   37.417  1   23.935 ? 339  ALA A C   1 
ATOM   2541 O  O   . ALA A 1 347 ? -15.223 7.945   36.684  1   22.739 ? 339  ALA A O   1 
ATOM   2542 C  CB  . ALA A 1 347 ? -15.106 8.066   39.683  1   21.384 ? 339  ALA A CB  1 
ATOM   2543 N  N   . PHE A 1 348 ? -17.417 7.474   37.142  1   20.705 ? 340  PHE A N   1 
ATOM   2544 C  CA  . PHE A 1 348 ? -17.731 6.836   35.869  1   21.157 ? 340  PHE A CA  1 
ATOM   2545 C  C   . PHE A 1 348 ? -18.854 7.621   35.191  1   20.724 ? 340  PHE A C   1 
ATOM   2546 O  O   . PHE A 1 348 ? -19.994 7.131   35.069  1   20.705 ? 340  PHE A O   1 
ATOM   2547 C  CB  . PHE A 1 348 ? -18.224 5.384   36.054  1   19.09  ? 340  PHE A CB  1 
ATOM   2548 C  CG  . PHE A 1 348 ? -17.202 4.302   36.389  1   20.164 ? 340  PHE A CG  1 
ATOM   2549 C  CD1 . PHE A 1 348 ? -15.82  4.566   36.415  1   21.505 ? 340  PHE A CD1 1 
ATOM   2550 C  CD2 . PHE A 1 348 ? -17.655 2.995   36.608  1   22.816 ? 340  PHE A CD2 1 
ATOM   2551 C  CE1 . PHE A 1 348 ? -14.908 3.529   36.624  1   20.985 ? 340  PHE A CE1 1 
ATOM   2552 C  CE2 . PHE A 1 348 ? -16.741 1.964   36.848  1   25.408 ? 340  PHE A CE2 1 
ATOM   2553 C  CZ  . PHE A 1 348 ? -15.388 2.236   36.874  1   21.641 ? 340  PHE A CZ  1 
ATOM   2554 N  N   . PRO A 1 349 ? -18.589 8.858   34.711  1   24.297 ? 341  PRO A N   1 
ATOM   2555 C  CA  . PRO A 1 349 ? -19.651 9.684   34.149  1   24.71  ? 341  PRO A CA  1 
ATOM   2556 C  C   . PRO A 1 349 ? -20.312 9.092   32.903  1   26.142 ? 341  PRO A C   1 
ATOM   2557 O  O   . PRO A 1 349 ? -21.397 9.533   32.541  1   25.737 ? 341  PRO A O   1 
ATOM   2558 C  CB  . PRO A 1 349 ? -18.951 10.996  33.839  1   26.488 ? 341  PRO A CB  1 
ATOM   2559 C  CG  . PRO A 1 349 ? -17.511 10.59   33.621  1   26.085 ? 341  PRO A CG  1 
ATOM   2560 C  CD  . PRO A 1 349 ? -17.293 9.563   34.701  1   21.179 ? 341  PRO A CD  1 
ATOM   2561 N  N   . PHE A 1 350 ? -19.667 8.09    32.29   1   25.961 ? 342  PHE A N   1 
ATOM   2562 C  CA  . PHE A 1 350 ? -20.183 7.371   31.118  1   23.703 ? 342  PHE A CA  1 
ATOM   2563 C  C   . PHE A 1 350 ? -21.363 6.453   31.508  1   23.781 ? 342  PHE A C   1 
ATOM   2564 O  O   . PHE A 1 350 ? -22.048 5.938   30.631  1   23.583 ? 342  PHE A O   1 
ATOM   2565 C  CB  . PHE A 1 350 ? -19.114 6.558   30.378  1   23.918 ? 342  PHE A CB  1 
ATOM   2566 C  CG  . PHE A 1 350 ? -18.191 5.765   31.305  1   24.089 ? 342  PHE A CG  1 
ATOM   2567 C  CD1 . PHE A 1 350 ? -17.023 6.354   31.818  1   25.587 ? 342  PHE A CD1 1 
ATOM   2568 C  CD2 . PHE A 1 350 ? -18.511 4.447   31.69   1   23.226 ? 342  PHE A CD2 1 
ATOM   2569 C  CE1 . PHE A 1 350 ? -16.186 5.641   32.691  1   24.039 ? 342  PHE A CE1 1 
ATOM   2570 C  CE2 . PHE A 1 350 ? -17.665 3.741   32.55   1   23.14  ? 342  PHE A CE2 1 
ATOM   2571 C  CZ  . PHE A 1 350 ? -16.515 4.331   33.038  1   24.391 ? 342  PHE A CZ  1 
ATOM   2572 N  N   . PHE A 1 351 ? -21.615 6.268   32.817  1   21.861 ? 343  PHE A N   1 
ATOM   2573 C  CA  . PHE A 1 351 ? -22.841 5.653   33.314  1   21.311 ? 343  PHE A CA  1 
ATOM   2574 C  C   . PHE A 1 351 ? -23.617 6.72    34.093  1   22.228 ? 343  PHE A C   1 
ATOM   2575 O  O   . PHE A 1 351 ? -23.7   6.68    35.335  1   22.345 ? 343  PHE A O   1 
ATOM   2576 C  CB  . PHE A 1 351 ? -22.576 4.401   34.173  1   21.414 ? 343  PHE A CB  1 
ATOM   2577 C  CG  . PHE A 1 351 ? -21.785 3.267   33.523  1   21.832 ? 343  PHE A CG  1 
ATOM   2578 C  CD1 . PHE A 1 351 ? -21.847 3.011   32.124  1   19.813 ? 343  PHE A CD1 1 
ATOM   2579 C  CD2 . PHE A 1 351 ? -20.974 2.436   34.32   1   20.822 ? 343  PHE A CD2 1 
ATOM   2580 C  CE1 . PHE A 1 351 ? -21.134 1.956   31.555  1   21.634 ? 343  PHE A CE1 1 
ATOM   2581 C  CE2 . PHE A 1 351 ? -20.24  1.403   33.742  1   21.238 ? 343  PHE A CE2 1 
ATOM   2582 C  CZ  . PHE A 1 351 ? -20.328 1.149   32.375  1   24.293 ? 343  PHE A CZ  1 
ATOM   2583 N  N   . PRO A 1 352 ? -24.235 7.691   33.397  1   23.628 ? 344  PRO A N   1 
ATOM   2584 C  CA  . PRO A 1 352 ? -24.885 8.788   34.101  1   23.387 ? 344  PRO A CA  1 
ATOM   2585 C  C   . PRO A 1 352 ? -26.17  8.36    34.817  1   24.579 ? 344  PRO A C   1 
ATOM   2586 O  O   . PRO A 1 352 ? -26.709 7.26    34.591  1   23.1   ? 344  PRO A O   1 
ATOM   2587 C  CB  . PRO A 1 352 ? -25.17  9.787   32.958  1   23.651 ? 344  PRO A CB  1 
ATOM   2588 C  CG  . PRO A 1 352 ? -25.464 8.847   31.772  1   25.767 ? 344  PRO A CG  1 
ATOM   2589 C  CD  . PRO A 1 352 ? -24.377 7.788   31.917  1   23.662 ? 344  PRO A CD  1 
ATOM   2590 N  N   . PRO A 1 353 ? -26.776 9.259   35.627  1   25.123 ? 345  PRO A N   1 
ATOM   2591 C  CA  . PRO A 1 353 ? -28.093 8.994   36.201  1   25.236 ? 345  PRO A CA  1 
ATOM   2592 C  C   . PRO A 1 353 ? -29.172 8.86    35.129  1   25.165 ? 345  PRO A C   1 
ATOM   2593 O  O   . PRO A 1 353 ? -28.962 9.28    33.992  1   28.099 ? 345  PRO A O   1 
ATOM   2594 C  CB  . PRO A 1 353 ? -28.349 10.232  37.039  1   23.858 ? 345  PRO A CB  1 
ATOM   2595 C  CG  . PRO A 1 353 ? -26.961 10.77   37.354  1   22.098 ? 345  PRO A CG  1 
ATOM   2596 C  CD  . PRO A 1 353 ? -26.221 10.564  36.062  1   23.085 ? 345  PRO A CD  1 
ATOM   2597 N  N   . ASP A 1 354 ? -30.294 8.251   35.507  1   27.895 ? 346  ASP A N   1 
ATOM   2598 C  CA  . ASP A 1 354 ? -31.456 8.095   34.628  1   35.166 ? 346  ASP A CA  1 
ATOM   2599 C  C   . ASP A 1 354 ? -32.173 9.423   34.381  1   36.613 ? 346  ASP A C   1 
ATOM   2600 O  O   . ASP A 1 354 ? -32.468 9.758   33.229  1   39.312 ? 346  ASP A O   1 
ATOM   2601 C  CB  . ASP A 1 354 ? -32.542 7.24    35.258  1   45.413 ? 346  ASP A CB  1 
ATOM   2602 C  CG  . ASP A 1 354 ? -32.468 5.738   35.058  1   48.652 ? 346  ASP A CG  1 
ATOM   2603 O  OD1 . ASP A 1 354 ? -32.412 5.281   33.899  1   45.175 ? 346  ASP A OD1 1 
ATOM   2604 O  OD2 . ASP A 1 354 ? -32.586 5.038   36.076  1   59.435 ? 346  ASP A OD2 1 
ATOM   2605 N  N   . SER A 1 355 ? -32.433 10.191  35.451  1   32.342 ? 347  SER A N   1 
ATOM   2606 C  CA  . SER A 1 355 ? -33.367 11.305  35.347  1   36.643 ? 347  SER A CA  1 
ATOM   2607 C  C   . SER A 1 355 ? -32.664 12.533  34.775  1   34.95  ? 347  SER A C   1 
ATOM   2608 O  O   . SER A 1 355 ? -31.46  12.72   34.964  1   31.184 ? 347  SER A O   1 
ATOM   2609 C  CB  . SER A 1 355 ? -34.02  11.612  36.682  1   35.902 ? 347  SER A CB  1 
ATOM   2610 O  OG  . SER A 1 355 ? -33.106 12.214  37.588  1   36.872 ? 347  SER A OG  1 
ATOM   2611 N  N   . ASP A 1 356 ? -33.437 13.392  34.101  1   34.703 ? 348  ASP A N   1 
ATOM   2612 C  CA  . ASP A 1 356 ? -32.928 14.652  33.577  1   36.391 ? 348  ASP A CA  1 
ATOM   2613 C  C   . ASP A 1 356 ? -32.315 15.467  34.703  1   31.544 ? 348  ASP A C   1 
ATOM   2614 O  O   . ASP A 1 356 ? -31.212 15.97   34.544  1   34.778 ? 348  ASP A O   1 
ATOM   2615 C  CB  . ASP A 1 356 ? -33.999 15.422  32.821  1   40.807 ? 348  ASP A CB  1 
ATOM   2616 C  CG  . ASP A 1 356 ? -34.265 14.953  31.403  1   48.047 ? 348  ASP A CG  1 
ATOM   2617 O  OD1 . ASP A 1 356 ? -33.628 13.981  30.941  1   51.121 ? 348  ASP A OD1 1 
ATOM   2618 O  OD2 . ASP A 1 356 ? -35.101 15.587  30.751  1   60.307 ? 348  ASP A OD2 1 
ATOM   2619 N  N   . GLU A 1 357 ? -33.019 15.548  35.84   1   32.626 ? 349  GLU A N   1 
ATOM   2620 C  CA  . GLU A 1 357 ? -32.56  16.309  36.992  1   31.467 ? 349  GLU A CA  1 
ATOM   2621 C  C   . GLU A 1 357 ? -31.178 15.835  37.457  1   33.036 ? 349  GLU A C   1 
ATOM   2622 O  O   . GLU A 1 357 ? -30.275 16.644  37.681  1   30.847 ? 349  GLU A O   1 
ATOM   2623 C  CB  . GLU A 1 357 ? -33.615 16.239  38.095  1   37.453 ? 349  GLU A CB  1 
ATOM   2624 C  CG  . GLU A 1 357 ? -33.164 16.797  39.44   1   52.514 ? 349  GLU A CG  1 
ATOM   2625 C  CD  . GLU A 1 357 ? -34.209 16.768  40.555  1   66.717 ? 349  GLU A CD  1 
ATOM   2626 O  OE1 . GLU A 1 357 ? -35.396 16.442  40.318  1   77.692 ? 349  GLU A OE1 1 
ATOM   2627 O  OE2 . GLU A 1 357 ? -33.828 17.095  41.698  1   73.079 ? 349  GLU A OE2 1 
ATOM   2628 N  N   . GLN A 1 358 ? -31.013 14.519  37.626  1   29.524 ? 350  GLN A N   1 
ATOM   2629 C  CA  . GLN A 1 358 ? -29.722 14.036  38.138  1   28.566 ? 350  GLN A CA  1 
ATOM   2630 C  C   . GLN A 1 358 ? -28.612 14.155  37.09   1   25.844 ? 350  GLN A C   1 
ATOM   2631 O  O   . GLN A 1 358 ? -27.45  14.382  37.451  1   26.215 ? 350  GLN A O   1 
ATOM   2632 C  CB  . GLN A 1 358 ? -29.861 12.602  38.651  1   29.398 ? 350  GLN A CB  1 
ATOM   2633 C  CG  . GLN A 1 358 ? -30.597 12.469  39.977  1   28.591 ? 350  GLN A CG  1 
ATOM   2634 C  CD  . GLN A 1 358 ? -30.261 11.185  40.699  1   31.734 ? 350  GLN A CD  1 
ATOM   2635 O  OE1 . GLN A 1 358 ? -29.15  10.665  40.556  1   29.021 ? 350  GLN A OE1 1 
ATOM   2636 N  NE2 . GLN A 1 358 ? -31.165 10.713  41.551  1   30.78  ? 350  GLN A NE2 1 
ATOM   2637 N  N   . LYS A 1 359 ? -28.965 13.974  35.801  1   27.186 ? 351  LYS A N   1 
ATOM   2638 C  CA  . LYS A 1 359 ? -28.015 14.186  34.715  1   27.665 ? 351  LYS A CA  1 
ATOM   2639 C  C   . LYS A 1 359 ? -27.488 15.616  34.752  1   32.191 ? 351  LYS A C   1 
ATOM   2640 O  O   . LYS A 1 359 ? -26.286 15.827  34.605  1   31.379 ? 351  LYS A O   1 
ATOM   2641 C  CB  . LYS A 1 359 ? -28.582 14.001  33.306  1   30.746 ? 351  LYS A CB  1 
ATOM   2642 C  CG  . LYS A 1 359 ? -28.729 12.55   32.937  1   35.433 ? 351  LYS A CG  1 
ATOM   2643 C  CD  . LYS A 1 359 ? -29.091 12.504  31.459  1   40.106 ? 351  LYS A CD  1 
ATOM   2644 C  CE  . LYS A 1 359 ? -29.143 11.122  30.89   1   48.508 ? 351  LYS A CE  1 
ATOM   2645 N  NZ  . LYS A 1 359 ? -30.319 10.428  31.428  1   57.004 ? 351  LYS A NZ  1 
ATOM   2646 N  N   . LYS A 1 360 ? -28.388 16.597  34.936  1   32.939 ? 352  LYS A N   1 
ATOM   2647 C  CA  . LYS A 1 360 ? -27.982 18.001  35.026  1   38.32  ? 352  LYS A CA  1 
ATOM   2648 C  C   . LYS A 1 360 ? -26.996 18.218  36.185  1   33.666 ? 352  LYS A C   1 
ATOM   2649 O  O   . LYS A 1 360 ? -26.007 18.946  36.014  1   36.746 ? 352  LYS A O   1 
ATOM   2650 C  CB  . LYS A 1 360 ? -29.189 18.93   35.22   1   38.404 ? 352  LYS A CB  1 
ATOM   2651 C  CG  . LYS A 1 360 ? -30.179 19.118  34.081  1   54.368 ? 352  LYS A CG  1 
ATOM   2652 C  CD  . LYS A 1 360 ? -31.267 20.069  34.594  1   59.21  ? 352  LYS A CD  1 
ATOM   2653 C  CE  . LYS A 1 360 ? -32.576 20.062  33.866  1   65.836 ? 352  LYS A CE  1 
ATOM   2654 N  NZ  . LYS A 1 360 ? -32.363 20.509  32.49   1   75.644 ? 352  LYS A NZ  1 
ATOM   2655 N  N   . LYS A 1 361 ? -27.265 17.572  37.335  1   33.451 ? 353  LYS A N   1 
ATOM   2656 C  CA  . LYS A 1 361 ? -26.4   17.633  38.502  1   29.086 ? 353  LYS A CA  1 
ATOM   2657 C  C   . LYS A 1 361 ? -24.994 17.092  38.169  1   33.481 ? 353  LYS A C   1 
ATOM   2658 O  O   . LYS A 1 361 ? -23.988 17.706  38.518  1   32.722 ? 353  LYS A O   1 
ATOM   2659 C  CB  . LYS A 1 361 ? -26.982 16.918  39.713  1   31.492 ? 353  LYS A CB  1 
ATOM   2660 C  CG  . LYS A 1 361 ? -26.064 16.995  40.907  1   32.768 ? 353  LYS A CG  1 
ATOM   2661 C  CD  . LYS A 1 361 ? -26.729 16.615  42.202  1   38.421 ? 353  LYS A CD  1 
ATOM   2662 C  CE  . LYS A 1 361 ? -25.832 16.571  43.396  1   47.504 ? 353  LYS A CE  1 
ATOM   2663 N  NZ  . LYS A 1 361 ? -24.679 17.46   43.3    1   45.393 ? 353  LYS A NZ  1 
ATOM   2664 N  N   . GLN A 1 362 ? -24.93  15.962  37.471  1   31.851 ? 354  GLN A N   1 
ATOM   2665 C  CA  . GLN A 1 362 ? -23.637 15.394  37.108  1   28.354 ? 354  GLN A CA  1 
ATOM   2666 C  C   . GLN A 1 362 ? -22.849 16.386  36.255  1   29.014 ? 354  GLN A C   1 
ATOM   2667 O  O   . GLN A 1 362 ? -21.671 16.577  36.499  1   31.269 ? 354  GLN A O   1 
ATOM   2668 C  CB  . GLN A 1 362 ? -23.785 14.009  36.465  1   28.85  ? 354  GLN A CB  1 
ATOM   2669 C  CG  . GLN A 1 362 ? -22.434 13.394  36.079  1   28.04  ? 354  GLN A CG  1 
ATOM   2670 C  CD  . GLN A 1 362 ? -22.574 12.039  35.417  1   27.977 ? 354  GLN A CD  1 
ATOM   2671 O  OE1 . GLN A 1 362 ? -22.979 11.068  36.065  1   27.498 ? 354  GLN A OE1 1 
ATOM   2672 N  NE2 . GLN A 1 362 ? -22.251 11.967  34.128  1   30.334 ? 354  GLN A NE2 1 
ATOM   2673 N  N   . GLU A 1 363 ? -23.509 17.031  35.278  1   30.226 ? 355  GLU A N   1 
ATOM   2674 C  CA  . GLU A 1 363 ? -22.856 17.991  34.39   1   38.882 ? 355  GLU A CA  1 
ATOM   2675 C  C   . GLU A 1 363 ? -22.374 19.191  35.211  1   41.09  ? 355  GLU A C   1 
ATOM   2676 O  O   . GLU A 1 363 ? -21.202 19.597  35.102  1   39.233 ? 355  GLU A O   1 
ATOM   2677 C  CB  . GLU A 1 363 ? -23.722 18.482  33.222  1   42.987 ? 355  GLU A CB  1 
ATOM   2678 C  CG  . GLU A 1 363 ? -24.41  17.416  32.376  1   60.705 ? 355  GLU A CG  1 
ATOM   2679 C  CD  . GLU A 1 363 ? -23.561 16.588  31.426  1   77.733 ? 355  GLU A CD  1 
ATOM   2680 O  OE1 . GLU A 1 363 ? -23.72  16.796  30.198  1   87.952 ? 355  GLU A OE1 1 
ATOM   2681 O  OE2 . GLU A 1 363 ? -22.781 15.723  31.896  1   76.337 ? 355  GLU A OE2 1 
ATOM   2682 N  N   . ALA A 1 364 ? -23.273 19.664  36.087  1   41.776 ? 356  ALA A N   1 
ATOM   2683 C  CA  . ALA A 1 364 ? -23.043 20.811  36.961  1   49.33  ? 356  ALA A CA  1 
ATOM   2684 C  C   . ALA A 1 364 ? -21.887 20.574  37.929  1   46.928 ? 356  ALA A C   1 
ATOM   2685 O  O   . ALA A 1 364 ? -21.114 21.494  38.167  1   51.315 ? 356  ALA A O   1 
ATOM   2686 C  CB  . ALA A 1 364 ? -24.304 21.224  37.711  1   49.024 ? 356  ALA A CB  1 
ATOM   2687 N  N   . ASP A 1 365 ? -21.796 19.373  38.517  1   47.857 ? 357  ASP A N   1 
ATOM   2688 C  CA  . ASP A 1 365 ? -20.809 19.069  39.549  1   41.017 ? 357  ASP A CA  1 
ATOM   2689 C  C   . ASP A 1 365 ? -19.372 19.212  39.025  1   37.672 ? 357  ASP A C   1 
ATOM   2690 O  O   . ASP A 1 365 ? -18.449 19.364  39.826  1   37.973 ? 357  ASP A O   1 
ATOM   2691 C  CB  . ASP A 1 365 ? -20.98  17.667  40.113  1   47.399 ? 357  ASP A CB  1 
ATOM   2692 C  CG  . ASP A 1 365 ? -21.955 17.506  41.271  1   55.434 ? 357  ASP A CG  1 
ATOM   2693 O  OD1 . ASP A 1 365 ? -22.531 18.53   41.71   1   51.714 ? 357  ASP A OD1 1 
ATOM   2694 O  OD2 . ASP A 1 365 ? -22.106 16.351  41.733  1   54.7   ? 357  ASP A OD2 1 
ATOM   2695 N  N   . GLY A 1 366 ? -19.198 19.084  37.698  1   32.469 ? 358  GLY A N   1 
ATOM   2696 C  CA  . GLY A 1 366 ? -17.874 19.089  37.091  1   31.344 ? 358  GLY A CA  1 
ATOM   2697 C  C   . GLY A 1 366 ? -17.083 17.872  37.583  1   33.149 ? 358  GLY A C   1 
ATOM   2698 O  O   . GLY A 1 366 ? -17.655 16.85   37.921  1   33.647 ? 358  GLY A O   1 
ATOM   2699 N  N   . THR A 1 367 ? -15.756 17.996  37.612  1   29.881 ? 359  THR A N   1 
ATOM   2700 C  CA  . THR A 1 367 ? -14.888 16.96   38.147  1   25.177 ? 359  THR A CA  1 
ATOM   2701 C  C   . THR A 1 367 ? -15.086 16.924  39.652  1   28.197 ? 359  THR A C   1 
ATOM   2702 O  O   . THR A 1 367 ? -14.847 17.944  40.307  1   26.714 ? 359  THR A O   1 
ATOM   2703 C  CB  . THR A 1 367 ? -13.425 17.236  37.798  1   25.659 ? 359  THR A CB  1 
ATOM   2704 O  OG1 . THR A 1 367 ? -13.383 17.231  36.37   1   25.557 ? 359  THR A OG1 1 
ATOM   2705 C  CG2 . THR A 1 367 ? -12.48  16.178  38.369  1   25.954 ? 359  THR A CG2 1 
ATOM   2706 N  N   . PRO A 1 368 ? -15.515 15.782  40.242  1   26.495 ? 360  PRO A N   1 
ATOM   2707 C  CA  . PRO A 1 368 ? -15.701 15.72   41.688  1   23.866 ? 360  PRO A CA  1 
ATOM   2708 C  C   . PRO A 1 368 ? -14.401 15.824  42.47   1   27.765 ? 360  PRO A C   1 
ATOM   2709 O  O   . PRO A 1 368 ? -13.318 15.541  41.96   1   24.003 ? 360  PRO A O   1 
ATOM   2710 C  CB  . PRO A 1 368 ? -16.432 14.398  41.945  1   24.324 ? 360  PRO A CB  1 
ATOM   2711 C  CG  . PRO A 1 368 ? -16.833 13.886  40.568  1   26.99  ? 360  PRO A CG  1 
ATOM   2712 C  CD  . PRO A 1 368 ? -15.885 14.519  39.572  1   26.666 ? 360  PRO A CD  1 
ATOM   2713 N  N   . LYS A 1 369 ? -14.538 16.292  43.719  1   23.85  ? 361  LYS A N   1 
ATOM   2714 C  CA  . LYS A 1 369 ? -13.46  16.254  44.684  1   23.404 ? 361  LYS A CA  1 
ATOM   2715 C  C   . LYS A 1 369 ? -13.136 14.778  44.939  1   23.89  ? 361  LYS A C   1 
ATOM   2716 O  O   . LYS A 1 369 ? -14.056 13.954  45.016  1   24.647 ? 361  LYS A O   1 
ATOM   2717 C  CB  . LYS A 1 369 ? -14.046 16.794  46.001  1   24.222 ? 361  LYS A CB  1 
ATOM   2718 C  CG  . LYS A 1 369 ? -12.921 17.023  47.047  1   29.078 ? 361  LYS A CG  1 
ATOM   2719 C  CD  . LYS A 1 369 ? -13.33  17.836  48.272  1   29.741 ? 361  LYS A CD  1 
ATOM   2720 C  CE  . LYS A 1 369 ? -12.296 17.582  49.337  1   31.389 ? 361  LYS A CE  1 
ATOM   2721 N  NZ  . LYS A 1 369 ? -10.928 18.024  48.954  1   32.291 ? 361  LYS A NZ  1 
ATOM   2722 N  N   . ALA A 1 370 ? -11.845 14.48   45.11   1   22.712 ? 362  ALA A N   1 
ATOM   2723 C  CA  . ALA A 1 370 ? -11.422 13.098  45.353  1   23.703 ? 362  ALA A CA  1 
ATOM   2724 C  C   . ALA A 1 370 ? -10.335 13.071  46.421  1   23.702 ? 362  ALA A C   1 
ATOM   2725 O  O   . ALA A 1 370 ? -9.447  13.922  46.415  1   23.136 ? 362  ALA A O   1 
ATOM   2726 C  CB  . ALA A 1 370 ? -10.911 12.529  44.032  1   23.173 ? 362  ALA A CB  1 
ATOM   2727 N  N   . GLN A 1 371 ? -10.447 12.104  47.351  1   21.375 ? 363  GLN A N   1 
ATOM   2728 C  CA  . GLN A 1 371 ? -9.556  11.983  48.491  1   23.275 ? 363  GLN A CA  1 
ATOM   2729 C  C   . GLN A 1 371 ? -9.31   10.514  48.812  1   26.206 ? 363  GLN A C   1 
ATOM   2730 O  O   . GLN A 1 371 ? -9.872  9.641   48.147  1   24.006 ? 363  GLN A O   1 
ATOM   2731 C  CB  . GLN A 1 371 ? -10.25  12.572  49.728  1   23.645 ? 363  GLN A CB  1 
ATOM   2732 C  CG  . GLN A 1 371 ? -10.566 14.057  49.615  1   27.599 ? 363  GLN A CG  1 
ATOM   2733 C  CD  . GLN A 1 371 ? -11.418 14.501  50.792  1   28.975 ? 363  GLN A CD  1 
ATOM   2734 O  OE1 . GLN A 1 371 ? -12.506 13.968  51.047  1   27.388 ? 363  GLN A OE1 1 
ATOM   2735 N  NE2 . GLN A 1 371 ? -10.938 15.505  51.508  1   28.208 ? 363  GLN A NE2 1 
ATOM   2736 N  N   . PHE A 1 372 ? -8.473  10.271  49.841  1   23.432 ? 364  PHE A N   1 
ATOM   2737 C  CA  . PHE A 1 372 ? -8.264  8.943   50.397  1   22.571 ? 364  PHE A CA  1 
ATOM   2738 C  C   . PHE A 1 372 ? -8.685  9.031   51.869  1   25.864 ? 364  PHE A C   1 
ATOM   2739 O  O   . PHE A 1 372 ? -8.264  9.966   52.563  1   24.266 ? 364  PHE A O   1 
ATOM   2740 C  CB  . PHE A 1 372 ? -6.782  8.6     50.297  1   22.682 ? 364  PHE A CB  1 
ATOM   2741 C  CG  . PHE A 1 372 ? -6.443  7.175   50.725  1   28.161 ? 364  PHE A CG  1 
ATOM   2742 C  CD1 . PHE A 1 372 ? -6.853  6.084   49.947  1   25.591 ? 364  PHE A CD1 1 
ATOM   2743 C  CD2 . PHE A 1 372 ? -5.701  6.945   51.893  1   27.34  ? 364  PHE A CD2 1 
ATOM   2744 C  CE1 . PHE A 1 372 ? -6.565  4.776   50.368  1   24.986 ? 364  PHE A CE1 1 
ATOM   2745 C  CE2 . PHE A 1 372 ? -5.369  5.647   52.298  1   29.522 ? 364  PHE A CE2 1 
ATOM   2746 C  CZ  . PHE A 1 372 ? -5.809  4.562   51.529  1   28.832 ? 364  PHE A CZ  1 
ATOM   2747 N  N   . VAL A 1 373 ? -9.614  8.16    52.293  1   22.789 ? 365  VAL A N   1 
ATOM   2748 C  CA  . VAL A 1 373 ? -10.305 8.36    53.581  1   22.51  ? 365  VAL A CA  1 
ATOM   2749 C  C   . VAL A 1 373 ? -10.302 7.077   54.405  1   27.043 ? 365  VAL A C   1 
ATOM   2750 O  O   . VAL A 1 373 ? -10.002 6.011   53.891  1   23.716 ? 365  VAL A O   1 
ATOM   2751 C  CB  . VAL A 1 373 ? -11.745 8.855   53.359  1   24.014 ? 365  VAL A CB  1 
ATOM   2752 C  CG1 . VAL A 1 373 ? -11.802 10.125  52.502  1   23.475 ? 365  VAL A CG1 1 
ATOM   2753 C  CG2 . VAL A 1 373 ? -12.683 7.754   52.814  1   24.097 ? 365  VAL A CG2 1 
ATOM   2754 N  N   . ARG A 1 374 ? -10.668 7.187   55.699  1   23.924 ? 366  ARG A N   1 
ATOM   2755 C  CA  . ARG A 1 374 ? -10.746 6.056   56.611  1   24.383 ? 366  ARG A CA  1 
ATOM   2756 C  C   . ARG A 1 374 ? -12.154 5.983   57.212  1   26.968 ? 366  ARG A C   1 
ATOM   2757 O  O   . ARG A 1 374 ? -12.645 6.97    57.751  1   25.765 ? 366  ARG A O   1 
ATOM   2758 C  CB  . ARG A 1 374 ? -9.726  6.25    57.749  1   24.896 ? 366  ARG A CB  1 
ATOM   2759 C  CG  . ARG A 1 374 ? -9.803  5.209   58.851  1   28.371 ? 366  ARG A CG  1 
ATOM   2760 C  CD  . ARG A 1 374 ? -8.553  5.21    59.738  1   30.526 ? 366  ARG A CD  1 
ATOM   2761 N  NE  . ARG A 1 374 ? -7.343  4.878   58.967  1   27.187 ? 366  ARG A NE  1 
ATOM   2762 C  CZ  . ARG A 1 374 ? -6.191  5.558   59.048  1   29.082 ? 366  ARG A CZ  1 
ATOM   2763 N  NH1 . ARG A 1 374 ? -5.854  6.235   60.165  1   25.406 ? 366  ARG A NH1 1 
ATOM   2764 N  NH2 . ARG A 1 374 ? -5.299  5.455   58.077  1   26.864 ? 366  ARG A NH2 1 
ATOM   2765 N  N   . TRP A 1 375 ? -12.768 4.795   57.135  1   26.226 ? 367  TRP A N   1 
ATOM   2766 C  CA  . TRP A 1 375 ? -14.12  4.509   57.616  1   25.328 ? 367  TRP A CA  1 
ATOM   2767 C  C   . TRP A 1 375 ? -14.008 3.75    58.925  1   25.456 ? 367  TRP A C   1 
ATOM   2768 O  O   . TRP A 1 375 ? -13.053 2.973   59.091  1   27.268 ? 367  TRP A O   1 
ATOM   2769 C  CB  . TRP A 1 375 ? -14.839 3.622   56.594  1   22.007 ? 367  TRP A CB  1 
ATOM   2770 C  CG  . TRP A 1 375 ? -14.91  4.21    55.211  1   22.772 ? 367  TRP A CG  1 
ATOM   2771 C  CD1 . TRP A 1 375 ? -14.042 3.99    54.18   1   24.16  ? 367  TRP A CD1 1 
ATOM   2772 C  CD2 . TRP A 1 375 ? -15.944 5.073   54.687  1   22.816 ? 367  TRP A CD2 1 
ATOM   2773 N  NE1 . TRP A 1 375 ? -14.438 4.682   53.056  1   22.287 ? 367  TRP A NE1 1 
ATOM   2774 C  CE2 . TRP A 1 375 ? -15.603 5.344   53.331  1   25.565 ? 367  TRP A CE2 1 
ATOM   2775 C  CE3 . TRP A 1 375 ? -17.125 5.638   55.217  1   24.686 ? 367  TRP A CE3 1 
ATOM   2776 C  CZ2 . TRP A 1 375 ? -16.397 6.164   52.523  1   26.015 ? 367  TRP A CZ2 1 
ATOM   2777 C  CZ3 . TRP A 1 375 ? -17.92  6.43    54.409  1   25.051 ? 367  TRP A CZ3 1 
ATOM   2778 C  CH2 . TRP A 1 375 ? -17.558 6.68    53.072  1   25.473 ? 367  TRP A CH2 1 
ATOM   2779 N  N   . THR A 1 376 ? -14.974 3.994   59.833  1   24.626 ? 368  THR A N   1 
ATOM   2780 C  CA  . THR A 1 376 ? -15.077 3.24    61.078  1   26.295 ? 368  THR A CA  1 
ATOM   2781 C  C   . THR A 1 376 ? -16.477 2.633   61.143  1   23.626 ? 368  THR A C   1 
ATOM   2782 O  O   . THR A 1 376 ? -17.457 3.365   61.112  1   25.062 ? 368  THR A O   1 
ATOM   2783 C  CB  . THR A 1 376 ? -14.777 4.088   62.319  1   29.036 ? 368  THR A CB  1 
ATOM   2784 O  OG1 . THR A 1 376 ? -13.449 4.577   62.185  1   29.239 ? 368  THR A OG1 1 
ATOM   2785 C  CG2 . THR A 1 376 ? -14.811 3.271   63.598  1   30.241 ? 368  THR A CG2 1 
ATOM   2786 N  N   . ILE A 1 377 ? -16.528 1.293   61.165  1   23.956 ? 369  ILE A N   1 
ATOM   2787 C  CA  . ILE A 1 377 ? -17.79  0.577   61.283  1   22.274 ? 369  ILE A CA  1 
ATOM   2788 C  C   . ILE A 1 377 ? -17.669 -0.212  62.58   1   25.105 ? 369  ILE A C   1 
ATOM   2789 O  O   . ILE A 1 377 ? -16.947 -1.214  62.656  1   26.882 ? 369  ILE A O   1 
ATOM   2790 C  CB  . ILE A 1 377 ? -18.092 -0.35   60.081  1   27.15  ? 369  ILE A CB  1 
ATOM   2791 C  CG1 . ILE A 1 377 ? -18.073 0.407   58.745  1   27.426 ? 369  ILE A CG1 1 
ATOM   2792 C  CG2 . ILE A 1 377 ? -19.419 -1.07   60.313  1   25.756 ? 369  ILE A CG2 1 
ATOM   2793 C  CD1 . ILE A 1 377 ? -18.046 -0.491  57.508  1   25.842 ? 369  ILE A CD1 1 
ATOM   2794 N  N   . ASP A 1 378 ? -18.342 0.304   63.594  1   26.548 ? 370  ASP A N   1 
ATOM   2795 C  CA  . ASP A 1 378 ? -18.285 -0.272  64.932  1   27.373 ? 370  ASP A CA  1 
ATOM   2796 C  C   . ASP A 1 378 ? -19.46  -1.252  65.081  1   26.512 ? 370  ASP A C   1 
ATOM   2797 O  O   . ASP A 1 378 ? -20.616 -0.838  65.141  1   30.004 ? 370  ASP A O   1 
ATOM   2798 C  CB  . ASP A 1 378 ? -18.321 0.828   65.987  1   29.126 ? 370  ASP A CB  1 
ATOM   2799 C  CG  . ASP A 1 378 ? -18.212 0.318   67.434  1   33.679 ? 370  ASP A CG  1 
ATOM   2800 O  OD1 . ASP A 1 378 ? -18.259 -0.941  67.66   1   30.288 ? 370  ASP A OD1 1 
ATOM   2801 O  OD2 . ASP A 1 378 ? -18.013 1.163   68.332  1   32.102 ? 370  ASP A OD2 1 
ATOM   2802 N  N   . PRO A 1 379 ? -19.211 -2.591  65.082  1   27.103 ? 371  PRO A N   1 
ATOM   2803 C  CA  . PRO A 1 379 ? -20.301 -3.568  65.135  1   31.999 ? 371  PRO A CA  1 
ATOM   2804 C  C   . PRO A 1 379 ? -21.116 -3.576  66.44   1   33.701 ? 371  PRO A C   1 
ATOM   2805 O  O   . PRO A 1 379 ? -22.175 -4.212  66.482  1   31.109 ? 371  PRO A O   1 
ATOM   2806 C  CB  . PRO A 1 379 ? -19.623 -4.918  64.895  1   34.095 ? 371  PRO A CB  1 
ATOM   2807 C  CG  . PRO A 1 379 ? -18.126 -4.649  64.925  1   33.673 ? 371  PRO A CG  1 
ATOM   2808 C  CD  . PRO A 1 379 ? -17.858 -3.194  65.096  1   30.266 ? 371  PRO A CD  1 
ATOM   2809 N  N   . ARG A 1 380 ? -20.62  -2.889  67.485  1   30.994 ? 372  ARG A N   1 
ATOM   2810 C  CA  . ARG A 1 380 ? -21.347 -2.686  68.739  1   34.783 ? 372  ARG A CA  1 
ATOM   2811 C  C   . ARG A 1 380 ? -22.515 -1.713  68.535  1   37.279 ? 372  ARG A C   1 
ATOM   2812 O  O   . ARG A 1 380 ? -23.477 -1.723  69.307  1   38.348 ? 372  ARG A O   1 
ATOM   2813 C  CB  . ARG A 1 380 ? -20.407 -2.25   69.874  1   32.953 ? 372  ARG A CB  1 
ATOM   2814 C  CG  . ARG A 1 380 ? -19.327 -3.29   70.154  1   33.138 ? 372  ARG A CG  1 
ATOM   2815 C  CD  . ARG A 1 380 ? -18.231 -2.747  71.085  1   43.34  ? 372  ARG A CD  1 
ATOM   2816 N  NE  . ARG A 1 380 ? -17.581 -1.537  70.559  1   41.952 ? 372  ARG A NE  1 
ATOM   2817 C  CZ  . ARG A 1 380 ? -16.588 -0.833  71.087  1   49.504 ? 372  ARG A CZ  1 
ATOM   2818 N  NH1 . ARG A 1 380 ? -15.857 -1.313  72.076  1   51.057 ? 372  ARG A NH1 1 
ATOM   2819 N  NH2 . ARG A 1 380 ? -16.283 0.339   70.557  1   49.266 ? 372  ARG A NH2 1 
ATOM   2820 N  N   . LYS A 1 381 ? -22.469 -0.909  67.46   1   32.969 ? 373  LYS A N   1 
ATOM   2821 C  CA  . LYS A 1 381 ? -23.437 0.17    67.252  1   31.544 ? 373  LYS A CA  1 
ATOM   2822 C  C   . LYS A 1 381 ? -24.65  -0.338  66.474  1   32.681 ? 373  LYS A C   1 
ATOM   2823 O  O   . LYS A 1 381 ? -24.598 -1.385  65.838  1   31.447 ? 373  LYS A O   1 
ATOM   2824 C  CB  . LYS A 1 381 ? -22.809 1.393   66.579  1   37.022 ? 373  LYS A CB  1 
ATOM   2825 C  CG  . LYS A 1 381 ? -21.759 2.11    67.391  1   39.228 ? 373  LYS A CG  1 
ATOM   2826 C  CD  . LYS A 1 381 ? -21.528 3.523   66.872  1   48.775 ? 373  LYS A CD  1 
ATOM   2827 C  CE  . LYS A 1 381 ? -22.377 4.555   67.547  1   60.605 ? 373  LYS A CE  1 
ATOM   2828 N  NZ  . LYS A 1 381 ? -21.968 4.687   68.951  1   62.897 ? 373  LYS A NZ  1 
ATOM   2829 N  N   . ASP A 1 382 ? -25.751 0.413   66.532  1   33.663 ? 374  ASP A N   1 
ATOM   2830 C  CA  . ASP A 1 382 ? -26.951 0.085   65.78   1   34.308 ? 374  ASP A CA  1 
ATOM   2831 C  C   . ASP A 1 382 ? -26.682 0.424   64.317  1   28.345 ? 374  ASP A C   1 
ATOM   2832 O  O   . ASP A 1 382 ? -26.441 1.582   64.014  1   31.016 ? 374  ASP A O   1 
ATOM   2833 C  CB  . ASP A 1 382 ? -28.16  0.836   66.328  1   38.358 ? 374  ASP A CB  1 
ATOM   2834 C  CG  . ASP A 1 382 ? -29.479 0.694   65.571  1   43.143 ? 374  ASP A CG  1 
ATOM   2835 O  OD1 . ASP A 1 382 ? -29.557 -0.084  64.594  1   36.741 ? 374  ASP A OD1 1 
ATOM   2836 O  OD2 . ASP A 1 382 ? -30.445 1.375   65.962  1   51.217 ? 374  ASP A OD2 1 
ATOM   2837 N  N   . ASN A 1 383 ? -26.764 -0.581  63.436  1   29.83  ? 375  ASN A N   1 
ATOM   2838 C  CA  . ASN A 1 383 ? -26.457 -0.395  62.015  1   31.842 ? 375  ASN A CA  1 
ATOM   2839 C  C   . ASN A 1 383 ? -27.477 0.501   61.298  1   34.211 ? 375  ASN A C   1 
ATOM   2840 O  O   . ASN A 1 383 ? -27.201 0.963   60.183  1   35.701 ? 375  ASN A O   1 
ATOM   2841 C  CB  . ASN A 1 383 ? -26.23  -1.732  61.302  1   28.726 ? 375  ASN A CB  1 
ATOM   2842 C  CG  . ASN A 1 383 ? -27.489 -2.564  61.272  1   30.329 ? 375  ASN A CG  1 
ATOM   2843 O  OD1 . ASN A 1 383 ? -27.923 -3.019  62.33   1   33.096 ? 375  ASN A OD1 1 
ATOM   2844 N  ND2 . ASN A 1 383 ? -28.104 -2.756  60.113  1   28.572 ? 375  ASN A ND2 1 
ATOM   2845 N  N   . ASN A 1 384 ? -28.647 0.748   61.92   1   32.693 ? 376  ASN A N   1 
ATOM   2846 C  CA  . ASN A 1 384 ? -29.638 1.666   61.368  1   34.153 ? 376  ASN A CA  1 
ATOM   2847 C  C   . ASN A 1 384 ? -29.199 3.125   61.512  1   31.702 ? 376  ASN A C   1 
ATOM   2848 O  O   . ASN A 1 384 ? -29.73  3.992   60.831  1   29.957 ? 376  ASN A O   1 
ATOM   2849 C  CB  . ASN A 1 384 ? -31.036 1.479   61.956  1   34.65  ? 376  ASN A CB  1 
ATOM   2850 C  CG  . ASN A 1 384 ? -31.639 0.133   61.636  1   44.709 ? 376  ASN A CG  1 
ATOM   2851 O  OD1 . ASN A 1 384 ? -32.263 -0.464  62.516  1   52.3   ? 376  ASN A OD1 1 
ATOM   2852 N  ND2 . ASN A 1 384 ? -31.57  -0.323  60.394  1   39.756 ? 376  ASN A ND2 1 
ATOM   2853 N  N   . GLU A 1 385 ? -28.234 3.394   62.399  1   29.777 ? 377  GLU A N   1 
ATOM   2854 C  CA  . GLU A 1 385 ? -27.736 4.741   62.592  1   34.549 ? 377  GLU A CA  1 
ATOM   2855 C  C   . GLU A 1 385 ? -26.703 5.002   61.498  1   34.453 ? 377  GLU A C   1 
ATOM   2856 O  O   . GLU A 1 385 ? -25.851 4.15    61.254  1   31.921 ? 377  GLU A O   1 
ATOM   2857 C  CB  . GLU A 1 385 ? -27.086 4.767   63.971  1   34.99  ? 377  GLU A CB  1 
ATOM   2858 C  CG  . GLU A 1 385 ? -26.532 6.128   64.374  1   43.803 ? 377  GLU A CG  1 
ATOM   2859 C  CD  . GLU A 1 385 ? -25.87  6       65.745  1   54.141 ? 377  GLU A CD  1 
ATOM   2860 O  OE1 . GLU A 1 385 ? -26.519 5.469   66.69   1   50.862 ? 377  GLU A OE1 1 
ATOM   2861 O  OE2 . GLU A 1 385 ? -24.678 6.389   65.852  1   49.128 ? 377  GLU A OE2 1 
ATOM   2862 N  N   . GLN A 1 386 ? -26.763 6.19    60.898  1   29.468 ? 378  GLN A N   1 
ATOM   2863 C  CA  . GLN A 1 386 ? -25.793 6.591   59.885  1   30.102 ? 378  GLN A CA  1 
ATOM   2864 C  C   . GLN A 1 386 ? -24.383 6.482   60.464  1   28.19  ? 378  GLN A C   1 
ATOM   2865 O  O   . GLN A 1 386 ? -24.124 6.808   61.632  1   25.407 ? 378  GLN A O   1 
ATOM   2866 C  CB  . GLN A 1 386 ? -26.2   7.954   59.353  1   32.118 ? 378  GLN A CB  1 
ATOM   2867 C  CG  . GLN A 1 386 ? -25.313 8.506   58.246  1   36.973 ? 378  GLN A CG  1 
ATOM   2868 C  CD  . GLN A 1 386 ? -25.838 9.841   57.756  1   43.359 ? 378  GLN A CD  1 
ATOM   2869 O  OE1 . GLN A 1 386 ? -25.854 10.822  58.501  1   40.435 ? 378  GLN A OE1 1 
ATOM   2870 N  NE2 . GLN A 1 386 ? -26.303 9.891   56.514  1   39.602 ? 378  GLN A NE2 1 
ATOM   2871 N  N   . LEU A 1 387 ? -23.459 5.989   59.627  1   23.952 ? 379  LEU A N   1 
ATOM   2872 C  CA  . LEU A 1 387 ? -22.053 5.885   59.987  1   23.092 ? 379  LEU A CA  1 
ATOM   2873 C  C   . LEU A 1 387 ? -21.478 7.276   60.234  1   24.768 ? 379  LEU A C   1 
ATOM   2874 O  O   . LEU A 1 387 ? -21.967 8.241   59.646  1   24.367 ? 379  LEU A O   1 
ATOM   2875 C  CB  . LEU A 1 387 ? -21.288 5.199   58.847  1   24.864 ? 379  LEU A CB  1 
ATOM   2876 C  CG  . LEU A 1 387 ? -21.495 3.683   58.722  1   29.148 ? 379  LEU A CG  1 
ATOM   2877 C  CD1 . LEU A 1 387 ? -20.863 3.231   57.388  1   24.492 ? 379  LEU A CD1 1 
ATOM   2878 C  CD2 . LEU A 1 387 ? -20.863 2.943   59.902  1   27.872 ? 379  LEU A CD2 1 
ATOM   2879 N  N   . PRO A 1 388 ? -20.432 7.393   61.089  1   24.359 ? 380  PRO A N   1 
ATOM   2880 C  CA  . PRO A 1 388 ? -19.679 8.633   61.196  1   27.004 ? 380  PRO A CA  1 
ATOM   2881 C  C   . PRO A 1 388 ? -18.99  8.997   59.882  1   32.742 ? 380  PRO A C   1 
ATOM   2882 O  O   . PRO A 1 388 ? -18.661 8.117   59.067  1   27.427 ? 380  PRO A O   1 
ATOM   2883 C  CB  . PRO A 1 388 ? -18.67  8.38    62.321  1   27.623 ? 380  PRO A CB  1 
ATOM   2884 C  CG  . PRO A 1 388 ? -18.541 6.86    62.348  1   29.909 ? 380  PRO A CG  1 
ATOM   2885 C  CD  . PRO A 1 388 ? -19.873 6.311   61.919  1   27.958 ? 380  PRO A CD  1 
ATOM   2886 N  N   . ASP A 1 389 ? -18.787 10.306  59.694  1   27.86  ? 381  ASP A N   1 
ATOM   2887 C  CA  . ASP A 1 389 ? -18.044 10.788  58.542  1   28.359 ? 381  ASP A CA  1 
ATOM   2888 C  C   . ASP A 1 389 ? -16.67  10.123  58.516  1   26.81  ? 381  ASP A C   1 
ATOM   2889 O  O   . ASP A 1 389 ? -16.021 9.96    59.553  1   27.693 ? 381  ASP A O   1 
ATOM   2890 C  CB  . ASP A 1 389 ? -17.92  12.305  58.501  1   30.091 ? 381  ASP A CB  1 
ATOM   2891 C  CG  . ASP A 1 389 ? -19.219 13.061  58.313  1   34.821 ? 381  ASP A CG  1 
ATOM   2892 O  OD1 . ASP A 1 389 ? -20.268 12.433  58.012  1   33.724 ? 381  ASP A OD1 1 
ATOM   2893 O  OD2 . ASP A 1 389 ? -19.187 14.293  58.485  1   33.271 ? 381  ASP A OD2 1 
ATOM   2894 N  N   . PRO A 1 390 ? -16.187 9.691   57.321  1   25.63  ? 382  PRO A N   1 
ATOM   2895 C  CA  . PRO A 1 390 ? -14.859 9.124   57.242  1   27.102 ? 382  PRO A CA  1 
ATOM   2896 C  C   . PRO A 1 390 ? -13.8   10.199  57.512  1   26.322 ? 382  PRO A C   1 
ATOM   2897 O  O   . PRO A 1 390 ? -14.059 11.37   57.289  1   28.963 ? 382  PRO A O   1 
ATOM   2898 C  CB  . PRO A 1 390 ? -14.804 8.515   55.824  1   24.429 ? 382  PRO A CB  1 
ATOM   2899 C  CG  . PRO A 1 390 ? -15.724 9.434   55.042  1   23.444 ? 382  PRO A CG  1 
ATOM   2900 C  CD  . PRO A 1 390 ? -16.883 9.723   56.023  1   25.379 ? 382  PRO A CD  1 
ATOM   2901 N  N   . GLU A 1 391 ? -12.631 9.774   57.976  1   25.411 ? 383  GLU A N   1 
ATOM   2902 C  CA  . GLU A 1 391 ? -11.535 10.689  58.254  1   24.8   ? 383  GLU A CA  1 
ATOM   2903 C  C   . GLU A 1 391 ? -10.708 10.842  56.975  1   30.693 ? 383  GLU A C   1 
ATOM   2904 O  O   . GLU A 1 391 ? -10.384 9.829   56.338  1   25.958 ? 383  GLU A O   1 
ATOM   2905 C  CB  . GLU A 1 391 ? -10.733 10.08   59.393  1   29.058 ? 383  GLU A CB  1 
ATOM   2906 C  CG  . GLU A 1 391 ? -9.53   10.947  59.769  1   35.057 ? 383  GLU A CG  1 
ATOM   2907 C  CD  . GLU A 1 391 ? -8.535  10.329  60.734  1   48.214 ? 383  GLU A CD  1 
ATOM   2908 O  OE1 . GLU A 1 391 ? -8.852  9.244   61.297  1   49.999 ? 383  GLU A OE1 1 
ATOM   2909 O  OE2 . GLU A 1 391 ? -7.442  10.923  60.921  1   45.397 ? 383  GLU A OE2 1 
ATOM   2910 N  N   . VAL A 1 392 ? -10.35  12.09   56.635  1   24.549 ? 384  VAL A N   1 
ATOM   2911 C  CA  . VAL A 1 392 ? -9.528  12.357  55.459  1   26.78  ? 384  VAL A CA  1 
ATOM   2912 C  C   . VAL A 1 392 ? -8.085  11.982  55.798  1   27.621 ? 384  VAL A C   1 
ATOM   2913 O  O   . VAL A 1 392 ? -7.507  12.477  56.772  1   26.038 ? 384  VAL A O   1 
ATOM   2914 C  CB  . VAL A 1 392 ? -9.638  13.814  54.95   1   29.207 ? 384  VAL A CB  1 
ATOM   2915 C  CG1 . VAL A 1 392 ? -8.798  14.046  53.694  1   26.127 ? 384  VAL A CG1 1 
ATOM   2916 C  CG2 . VAL A 1 392 ? -11.081 14.232  54.688  1   30.212 ? 384  VAL A CG2 1 
ATOM   2917 N  N   . ILE A 1 393 ? -7.513  11.082  54.991  1   24.25  ? 385  ILE A N   1 
ATOM   2918 C  CA  . ILE A 1 393 ? -6.155  10.581  55.189  1   23.556 ? 385  ILE A CA  1 
ATOM   2919 C  C   . ILE A 1 393 ? -5.221  11.302  54.224  1   26.814 ? 385  ILE A C   1 
ATOM   2920 O  O   . ILE A 1 393 ? -4.208  11.843  54.655  1   25.17  ? 385  ILE A O   1 
ATOM   2921 C  CB  . ILE A 1 393 ? -6.068  9.045   55.085  1   22.905 ? 385  ILE A CB  1 
ATOM   2922 C  CG1 . ILE A 1 393 ? -6.963  8.348   56.143  1   23.054 ? 385  ILE A CG1 1 
ATOM   2923 C  CG2 . ILE A 1 393 ? -4.603  8.567   55.14   1   22.102 ? 385  ILE A CG2 1 
ATOM   2924 C  CD1 . ILE A 1 393 ? -6.657  8.707   57.611  1   29.008 ? 385  ILE A CD1 1 
ATOM   2925 N  N   . LEU A 1 394 ? -5.586  11.307  52.938  1   25.786 ? 386  LEU A N   1 
ATOM   2926 C  CA  . LEU A 1 394 ? -4.911  12.108  51.931  1   24.583 ? 386  LEU A CA  1 
ATOM   2927 C  C   . LEU A 1 394 ? -5.932  13.014  51.267  1   26.161 ? 386  LEU A C   1 
ATOM   2928 O  O   . LEU A 1 394 ? -6.94   12.538  50.705  1   24.654 ? 386  LEU A O   1 
ATOM   2929 C  CB  . LEU A 1 394 ? -4.141  11.317  50.866  1   25.884 ? 386  LEU A CB  1 
ATOM   2930 C  CG  . LEU A 1 394 ? -3.112  10.296  51.358  1   30.229 ? 386  LEU A CG  1 
ATOM   2931 C  CD1 . LEU A 1 394 ? -2.577  9.65    50.068  1   32.634 ? 386  LEU A CD1 1 
ATOM   2932 C  CD2 . LEU A 1 394 ? -1.967  10.944  52.141  1   28.714 ? 386  LEU A CD2 1 
ATOM   2933 N  N   . ASP A 1 395 ? -5.614  14.32   51.288  1   23.521 ? 387  ASP A N   1 
ATOM   2934 C  CA  . ASP A 1 395 ? -6.482  15.3    50.66   1   25.998 ? 387  ASP A CA  1 
ATOM   2935 C  C   . ASP A 1 395 ? -6.103  15.525  49.2    1   26.784 ? 387  ASP A C   1 
ATOM   2936 O  O   . ASP A 1 395 ? -5.936  16.66   48.751  1   28.536 ? 387  ASP A O   1 
ATOM   2937 C  CB  . ASP A 1 395 ? -6.538  16.58   51.486  1   26.915 ? 387  ASP A CB  1 
ATOM   2938 C  CG  . ASP A 1 395 ? -7.704  17.49   51.12   1   29.828 ? 387  ASP A CG  1 
ATOM   2939 O  OD1 . ASP A 1 395 ? -8.729  16.983  50.549  1   30.497 ? 387  ASP A OD1 1 
ATOM   2940 O  OD2 . ASP A 1 395 ? -7.551  18.711  51.342  1   32.621 ? 387  ASP A OD2 1 
ATOM   2941 N  N   . THR A 1 396 ? -5.904  14.43   48.444  1   25.541 ? 388  THR A N   1 
ATOM   2942 C  CA  . THR A 1 396 ? -5.547  14.541  47.042  1   24.351 ? 388  THR A CA  1 
ATOM   2943 C  C   . THR A 1 396 ? -6.252  13.401  46.307  1   24.323 ? 388  THR A C   1 
ATOM   2944 O  O   . THR A 1 396 ? -6.507  12.369  46.941  1   24.743 ? 388  THR A O   1 
ATOM   2945 C  CB  . THR A 1 396 ? -4.02   14.501  46.857  1   28.19  ? 388  THR A CB  1 
ATOM   2946 O  OG1 . THR A 1 396 ? -3.747  15.014  45.549  1   27.531 ? 388  THR A OG1 1 
ATOM   2947 C  CG2 . THR A 1 396 ? -3.385  13.121  47.005  1   25.131 ? 388  THR A CG2 1 
ATOM   2948 N  N   . PRO A 1 397 ? -6.581  13.543  45      1   25.745 ? 389  PRO A N   1 
ATOM   2949 C  CA  . PRO A 1 397 ? -7.096  12.404  44.247  1   23.812 ? 389  PRO A CA  1 
ATOM   2950 C  C   . PRO A 1 397 ? -6.166  11.206  44.354  1   24.79  ? 389  PRO A C   1 
ATOM   2951 O  O   . PRO A 1 397 ? -4.933  11.354  44.195  1   24.428 ? 389  PRO A O   1 
ATOM   2952 C  CB  . PRO A 1 397 ? -7.317  12.926  42.835  1   23.438 ? 389  PRO A CB  1 
ATOM   2953 C  CG  . PRO A 1 397 ? -7.498  14.438  43.057  1   27.22  ? 389  PRO A CG  1 
ATOM   2954 C  CD  . PRO A 1 397 ? -6.535  14.77   44.182  1   24.553 ? 389  PRO A CD  1 
ATOM   2955 N  N   . SER A 1 398 ? -6.789  10.074  44.736  1   22.923 ? 390  SER A N   1 
ATOM   2956 C  CA  . SER A 1 398 ? -6.098  8.859   45.128  1   24.2   ? 390  SER A CA  1 
ATOM   2957 C  C   . SER A 1 398 ? -6.868  7.69    44.54   1   24.528 ? 390  SER A C   1 
ATOM   2958 O  O   . SER A 1 398 ? -8.09   7.666   44.577  1   25.318 ? 390  SER A O   1 
ATOM   2959 C  CB  . SER A 1 398 ? -6.092  8.725   46.638  1   24.604 ? 390  SER A CB  1 
ATOM   2960 O  OG  . SER A 1 398 ? -5.293  9.747   47.223  1   26.371 ? 390  SER A OG  1 
ATOM   2961 N  N   . GLU A 1 399 ? -6.138  6.729   43.965  1   24.347 ? 391  GLU A N   1 
ATOM   2962 C  CA  . GLU A 1 399 ? -6.811  5.55    43.44   1   20.759 ? 391  GLU A CA  1 
ATOM   2963 C  C   . GLU A 1 399 ? -5.823  4.387   43.476  1   17.339 ? 391  GLU A C   1 
ATOM   2964 O  O   . GLU A 1 399 ? -4.671  4.555   43.867  1   22.288 ? 391  GLU A O   1 
ATOM   2965 C  CB  . GLU A 1 399 ? -7.551  5.808   42.114  1   22.304 ? 391  GLU A CB  1 
ATOM   2966 C  CG  . GLU A 1 399 ? -9.078  5.64    42.251  1   26.801 ? 391  GLU A CG  1 
ATOM   2967 C  CD  . GLU A 1 399 ? -9.385  4.231   42.725  1   29.037 ? 391  GLU A CD  1 
ATOM   2968 O  OE1 . GLU A 1 399 ? -9      3.322   41.977  1   29.518 ? 391  GLU A OE1 1 
ATOM   2969 O  OE2 . GLU A 1 399 ? -9.808  3.99    43.857  1   29.857 ? 391  GLU A OE2 1 
ATOM   2970 N  N   . PHE A 1 400 ? -6.323  3.2     43.113  1   19.338 ? 392  PHE A N   1 
ATOM   2971 C  CA  . PHE A 1 400 ? -5.567  1.964   42.975  1   19.151 ? 392  PHE A CA  1 
ATOM   2972 C  C   . PHE A 1 400 ? -4.621  1.755   44.159  1   21.031 ? 392  PHE A C   1 
ATOM   2973 O  O   . PHE A 1 400 ? -3.416  1.603   43.958  1   20.962 ? 392  PHE A O   1 
ATOM   2974 C  CB  . PHE A 1 400 ? -4.765  1.953   41.666  1   20.157 ? 392  PHE A CB  1 
ATOM   2975 C  CG  . PHE A 1 400 ? -5.697  1.924   40.463  1   18.937 ? 392  PHE A CG  1 
ATOM   2976 C  CD1 . PHE A 1 400 ? -6.487  0.794   40.217  1   24.054 ? 392  PHE A CD1 1 
ATOM   2977 C  CD2 . PHE A 1 400 ? -5.742  3.002   39.573  1   20.828 ? 392  PHE A CD2 1 
ATOM   2978 C  CE1 . PHE A 1 400 ? -7.328  0.742   39.101  1   24.366 ? 392  PHE A CE1 1 
ATOM   2979 C  CE2 . PHE A 1 400 ? -6.572  2.956   38.446  1   22.217 ? 392  PHE A CE2 1 
ATOM   2980 C  CZ  . PHE A 1 400 ? -7.354  1.818   38.204  1   21.721 ? 392  PHE A CZ  1 
ATOM   2981 N  N   . PRO A 1 401 ? -5.115  1.723   45.414  1   21.406 ? 393  PRO A N   1 
ATOM   2982 C  CA  . PRO A 1 401 ? -4.221  1.439   46.532  1   19.909 ? 393  PRO A CA  1 
ATOM   2983 C  C   . PRO A 1 401 ? -3.924  -0.052  46.687  1   20.232 ? 393  PRO A C   1 
ATOM   2984 O  O   . PRO A 1 401 ? -4.793  -0.895  46.436  1   22.101 ? 393  PRO A O   1 
ATOM   2985 C  CB  . PRO A 1 401 ? -5.059  1.857   47.733  1   19.459 ? 393  PRO A CB  1 
ATOM   2986 C  CG  . PRO A 1 401 ? -6.512  1.655   47.306  1   22.244 ? 393  PRO A CG  1 
ATOM   2987 C  CD  . PRO A 1 401 ? -6.52   1.963   45.825  1   21.425 ? 393  PRO A CD  1 
ATOM   2988 N  N   . GLN A 1 402 ? -2.714  -0.361  47.146  1   20.115 ? 394  GLN A N   1 
ATOM   2989 C  CA  . GLN A 1 402 ? -2.416  -1.727  47.525  1   20.207 ? 394  GLN A CA  1 
ATOM   2990 C  C   . GLN A 1 402 ? -1.739  -1.694  48.884  1   21.774 ? 394  GLN A C   1 
ATOM   2991 O  O   . GLN A 1 402 ? -1.325  -0.613  49.339  1   22.166 ? 394  GLN A O   1 
ATOM   2992 C  CB  . GLN A 1 402 ? -1.515  -2.416  46.508  1   21.129 ? 394  GLN A CB  1 
ATOM   2993 C  CG  . GLN A 1 402 ? -2.198  -2.712  45.176  1   21.051 ? 394  GLN A CG  1 
ATOM   2994 C  CD  . GLN A 1 402 ? -1.696  -3.972  44.493  1   22.29  ? 394  GLN A CD  1 
ATOM   2995 O  OE1 . GLN A 1 402 ? -0.736  -4.624  44.936  1   22.669 ? 394  GLN A OE1 1 
ATOM   2996 N  NE2 . GLN A 1 402 ? -2.325  -4.319  43.37   1   22.475 ? 394  GLN A NE2 1 
ATOM   2997 N  N   . ILE A 1 403 ? -1.624  -2.879  49.483  1   21.366 ? 395  ILE A N   1 
ATOM   2998 C  CA  . ILE A 1 403 ? -0.921  -2.974  50.758  1   24.445 ? 395  ILE A CA  1 
ATOM   2999 C  C   . ILE A 1 403 ? 0.237   -3.963  50.631  1   21.819 ? 395  ILE A C   1 
ATOM   3000 O  O   . ILE A 1 403 ? 0.501   -4.508  49.557  1   22.98  ? 395  ILE A O   1 
ATOM   3001 C  CB  . ILE A 1 403 ? -1.898  -3.331  51.921  1   21.874 ? 395  ILE A CB  1 
ATOM   3002 C  CG1 . ILE A 1 403 ? -2.472  -4.791  51.756  1   25.453 ? 395  ILE A CG1 1 
ATOM   3003 C  CG2 . ILE A 1 403 ? -3.006  -2.278  52.049  1   24.478 ? 395  ILE A CG2 1 
ATOM   3004 C  CD1 . ILE A 1 403 ? -2.915  -5.454  53.05   1   26.056 ? 395  ILE A CD1 1 
ATOM   3005 N  N   . ASP A 1 404 ? 0.939   -4.178  51.771  1   23.166 ? 396  ASP A N   1 
ATOM   3006 C  CA  . ASP A 1 404 ? 1.858   -5.301  51.89   1   25.45  ? 396  ASP A CA  1 
ATOM   3007 C  C   . ASP A 1 404 ? 0.978   -6.531  52.148  1   24.154 ? 396  ASP A C   1 
ATOM   3008 O  O   . ASP A 1 404 ? 0.428   -6.674  53.249  1   23.586 ? 396  ASP A O   1 
ATOM   3009 C  CB  . ASP A 1 404 ? 2.873   -4.988  52.985  1   24.377 ? 396  ASP A CB  1 
ATOM   3010 C  CG  . ASP A 1 404 ? 3.901   -6.069  53.301  1   24.693 ? 396  ASP A CG  1 
ATOM   3011 O  OD1 . ASP A 1 404 ? 3.71    -7.242  52.896  1   24.785 ? 396  ASP A OD1 1 
ATOM   3012 O  OD2 . ASP A 1 404 ? 4.892   -5.719  53.965  1   27.232 ? 396  ASP A OD2 1 
ATOM   3013 N  N   . ASN A 1 405 ? 0.902   -7.426  51.148  1   24.015 ? 397  ASN A N   1 
ATOM   3014 C  CA  . ASN A 1 405 ? 0       -8.583  51.14   1   25.894 ? 397  ASN A CA  1 
ATOM   3015 C  C   . ASN A 1 405 ? 0.234   -9.579  52.279  1   27.824 ? 397  ASN A C   1 
ATOM   3016 O  O   . ASN A 1 405 ? -0.648  -10.383 52.568  1   26.909 ? 397  ASN A O   1 
ATOM   3017 C  CB  . ASN A 1 405 ? 0.057   -9.3    49.794  1   27.049 ? 397  ASN A CB  1 
ATOM   3018 C  CG  . ASN A 1 405 ? -0.589  -8.435  48.736  1   32.943 ? 397  ASN A CG  1 
ATOM   3019 O  OD1 . ASN A 1 405 ? -1.558  -7.734  49.038  1   32.83  ? 397  ASN A OD1 1 
ATOM   3020 N  ND2 . ASN A 1 405 ? -0.024  -8.433  47.535  1   35.823 ? 397  ASN A ND2 1 
ATOM   3021 N  N   . ARG A 1 406 ? 1.406   -9.501  52.934  1   26.457 ? 398  ARG A N   1 
ATOM   3022 C  CA  . ARG A 1 406 ? 1.653   -10.264 54.148  1   25.801 ? 398  ARG A CA  1 
ATOM   3023 C  C   . ARG A 1 406 ? 0.698   -9.88   55.289  1   25.97  ? 398  ARG A C   1 
ATOM   3024 O  O   . ARG A 1 406 ? 0.637   -10.601 56.289  1   25.331 ? 398  ARG A O   1 
ATOM   3025 C  CB  . ARG A 1 406 ? 3.12    -10.139 54.574  1   26.022 ? 398  ARG A CB  1 
ATOM   3026 C  CG  . ARG A 1 406 ? 4.003   -10.762 53.51   1   26.117 ? 398  ARG A CG  1 
ATOM   3027 C  CD  . ARG A 1 406 ? 5.465   -10.464 53.891  1   26.367 ? 398  ARG A CD  1 
ATOM   3028 N  NE  . ARG A 1 406 ? 5.749   -9.027  54.022  1   24.124 ? 398  ARG A NE  1 
ATOM   3029 C  CZ  . ARG A 1 406 ? 6.85    -8.525  54.595  1   27.369 ? 398  ARG A CZ  1 
ATOM   3030 N  NH1 . ARG A 1 406 ? 7.77    -9.361  55.073  1   29.453 ? 398  ARG A NH1 1 
ATOM   3031 N  NH2 . ARG A 1 406 ? 7.035   -7.209  54.708  1   26.431 ? 398  ARG A NH2 1 
ATOM   3032 N  N   . PHE A 1 407 ? -0.017  -8.746  55.16   1   24.56  ? 399  PHE A N   1 
ATOM   3033 C  CA  . PHE A 1 407 ? -0.872  -8.205  56.215  1   27.656 ? 399  PHE A CA  1 
ATOM   3034 C  C   . PHE A 1 407 ? -2.347  -8.174  55.807  1   24.397 ? 399  PHE A C   1 
ATOM   3035 O  O   . PHE A 1 407 ? -3.142  -7.432  56.386  1   26.753 ? 399  PHE A O   1 
ATOM   3036 C  CB  . PHE A 1 407 ? -0.376  -6.822  56.657  1   26.118 ? 399  PHE A CB  1 
ATOM   3037 C  CG  . PHE A 1 407 ? 1.015   -6.916  57.273  1   27.6   ? 399  PHE A CG  1 
ATOM   3038 C  CD1 . PHE A 1 407 ? 2.162   -6.915  56.463  1   26.096 ? 399  PHE A CD1 1 
ATOM   3039 C  CD2 . PHE A 1 407 ? 1.163   -7.04   58.667  1   30.809 ? 399  PHE A CD2 1 
ATOM   3040 C  CE1 . PHE A 1 407 ? 3.434   -7.065  57.03   1   25.788 ? 399  PHE A CE1 1 
ATOM   3041 C  CE2 . PHE A 1 407 ? 2.446   -7.165  59.24   1   32.888 ? 399  PHE A CE2 1 
ATOM   3042 C  CZ  . PHE A 1 407 ? 3.572   -7.164  58.426  1   28.873 ? 399  PHE A CZ  1 
ATOM   3043 N  N   . MET A 1 408 ? -2.731  -9.046  54.869  1   24.4   ? 400  MET A N   1 
ATOM   3044 C  CA  . MET A 1 408 ? -4.098  -8.99   54.367  1   25.753 ? 400  MET A CA  1 
ATOM   3045 C  C   . MET A 1 408 ? -5.029  -9.669  55.376  1   26.012 ? 400  MET A C   1 
ATOM   3046 O  O   . MET A 1 408 ? -4.782  -10.805 55.788  1   26.813 ? 400  MET A O   1 
ATOM   3047 C  CB  . MET A 1 408 ? -4.153  -9.601  52.96   1   24.524 ? 400  MET A CB  1 
ATOM   3048 C  CG  . MET A 1 408 ? -5.588  -9.804  52.423  1   24.42  ? 400  MET A CG  1 
ATOM   3049 S  SD  . MET A 1 408 ? -6.521  -8.254  52.441  1   25.292 ? 400  MET A SD  1 
ATOM   3050 C  CE  . MET A 1 408 ? -5.766  -7.482  51.016  1   23.537 ? 400  MET A CE  1 
ATOM   3051 N  N   . GLY A 1 409 ? -6.093  -8.959  55.763  1   24.547 ? 401  GLY A N   1 
ATOM   3052 C  CA  . GLY A 1 409 ? -7.111  -9.477  56.669  1   26.48  ? 401  GLY A CA  1 
ATOM   3053 C  C   . GLY A 1 409 ? -6.692  -9.378  58.137  1   29.686 ? 401  GLY A C   1 
ATOM   3054 O  O   . GLY A 1 409 ? -7.341  -9.981  58.979  1   27.805 ? 401  GLY A O   1 
ATOM   3055 N  N   . VAL A 1 410 ? -5.587  -8.668  58.404  1   23.994 ? 402  VAL A N   1 
ATOM   3056 C  CA  . VAL A 1 410 ? -5.136  -8.368  59.76   1   27.939 ? 402  VAL A CA  1 
ATOM   3057 C  C   . VAL A 1 410 ? -4.771  -6.887  59.797  1   29.944 ? 402  VAL A C   1 
ATOM   3058 O  O   . VAL A 1 410 ? -4.75   -6.216  58.756  1   27.338 ? 402  VAL A O   1 
ATOM   3059 C  CB  . VAL A 1 410 ? -3.941  -9.26   60.184  1   24.868 ? 402  VAL A CB  1 
ATOM   3060 C  CG1 . VAL A 1 410 ? -4.321  -10.73  60.277  1   25.65  ? 402  VAL A CG1 1 
ATOM   3061 C  CG2 . VAL A 1 410 ? -2.719  -9.086  59.281  1   28.092 ? 402  VAL A CG2 1 
ATOM   3062 N  N   . GLU A 1 411 ? -4.43   -6.374  60.985  1   26.103 ? 403  GLU A N   1 
ATOM   3063 C  CA  . GLU A 1 411 ? -3.983  -4.989  61.051  1   27.242 ? 403  GLU A CA  1 
ATOM   3064 C  C   . GLU A 1 411 ? -2.794  -4.734  60.109  1   29.87  ? 403  GLU A C   1 
ATOM   3065 O  O   . GLU A 1 411 ? -1.837  -5.51   60.069  1   28.021 ? 403  GLU A O   1 
ATOM   3066 C  CB  . GLU A 1 411 ? -3.638  -4.665  62.502  1   30.643 ? 403  GLU A CB  1 
ATOM   3067 C  CG  . GLU A 1 411 ? -3.2    -3.213  62.621  1   27.41  ? 403  GLU A CG  1 
ATOM   3068 C  CD  . GLU A 1 411 ? -2.903  -2.763  64.038  1   37.425 ? 403  GLU A CD  1 
ATOM   3069 O  OE1 . GLU A 1 411 ? -3.077  -3.602  64.951  1   38.574 ? 403  GLU A OE1 1 
ATOM   3070 O  OE2 . GLU A 1 411 ? -2.529  -1.575  64.213  1   34.668 ? 403  GLU A OE2 1 
ATOM   3071 N  N   . TYR A 1 412 ? -2.893  -3.641  59.333  1   26.368 ? 404  TYR A N   1 
ATOM   3072 C  CA  . TYR A 1 412 ? -1.836  -3.258  58.395  1   28.74  ? 404  TYR A CA  1 
ATOM   3073 C  C   . TYR A 1 412 ? -1.583  -1.773  58.613  1   25.582 ? 404  TYR A C   1 
ATOM   3074 O  O   . TYR A 1 412 ? -2.419  -1.111  59.212  1   25.624 ? 404  TYR A O   1 
ATOM   3075 C  CB  . TYR A 1 412 ? -2.286  -3.607  56.962  1   25.998 ? 404  TYR A CB  1 
ATOM   3076 C  CG  . TYR A 1 412 ? -3.285  -2.6    56.415  1   26.529 ? 404  TYR A CG  1 
ATOM   3077 C  CD1 . TYR A 1 412 ? -4.661  -2.669  56.731  1   24.437 ? 404  TYR A CD1 1 
ATOM   3078 C  CD2 . TYR A 1 412 ? -2.853  -1.593  55.544  1   27.678 ? 404  TYR A CD2 1 
ATOM   3079 C  CE1 . TYR A 1 412 ? -5.56   -1.702  56.272  1   24.828 ? 404  TYR A CE1 1 
ATOM   3080 C  CE2 . TYR A 1 412 ? -3.757  -0.654  55.05   1   25.84  ? 404  TYR A CE2 1 
ATOM   3081 C  CZ  . TYR A 1 412 ? -5.102  -0.718  55.404  1   24.598 ? 404  TYR A CZ  1 
ATOM   3082 O  OH  . TYR A 1 412 ? -5.97   0.238   54.923  1   25.566 ? 404  TYR A OH  1 
ATOM   3083 N  N   . SER A 1 413 ? -0.465  -1.259  58.072  1   25.631 ? 405  SER A N   1 
ATOM   3084 C  CA  . SER A 1 413 ? -0.035  0.12    58.239  1   24.88  ? 405  SER A CA  1 
ATOM   3085 C  C   . SER A 1 413 ? 0.341   0.755   56.895  1   26.745 ? 405  SER A C   1 
ATOM   3086 O  O   . SER A 1 413 ? -0.041  1.897   56.636  1   27.971 ? 405  SER A O   1 
ATOM   3087 C  CB  . SER A 1 413 ? 1.091   0.185   59.258  1   24.596 ? 405  SER A CB  1 
ATOM   3088 O  OG  . SER A 1 413 ? 1.601   1.516   59.322  1   28.918 ? 405  SER A OG  1 
ATOM   3089 N  N   . SER A 1 414 ? 1.086   0.028   56.055  1   24.368 ? 406  SER A N   1 
ATOM   3090 C  CA  . SER A 1 414 ? 1.531   0.54    54.751  1   24.943 ? 406  SER A CA  1 
ATOM   3091 C  C   . SER A 1 414 ? 0.408   0.477   53.722  1   24.307 ? 406  SER A C   1 
ATOM   3092 O  O   . SER A 1 414 ? -0.244  -0.573  53.565  1   25.575 ? 406  SER A O   1 
ATOM   3093 C  CB  . SER A 1 414 ? 2.764   -0.19   54.244  1   24.948 ? 406  SER A CB  1 
ATOM   3094 O  OG  . SER A 1 414 ? 3.959   0.34    54.823  1   25.934 ? 406  SER A OG  1 
ATOM   3095 N  N   . ALA A 1 415 ? 0.248   1.584   52.996  1   24.345 ? 407  ALA A N   1 
ATOM   3096 C  CA  . ALA A 1 415 ? -0.538  1.601   51.763  1   24.31  ? 407  ALA A CA  1 
ATOM   3097 C  C   . ALA A 1 415 ? 0.302   2.264   50.671  1   25.986 ? 407  ALA A C   1 
ATOM   3098 O  O   . ALA A 1 415 ? 0.958   3.29    50.899  1   23.036 ? 407  ALA A O   1 
ATOM   3099 C  CB  . ALA A 1 415 ? -1.838  2.342   51.973  1   22.819 ? 407  ALA A CB  1 
ATOM   3100 N  N   . PHE A 1 416 ? 0.195   1.704   49.461  1   22.463 ? 408  PHE A N   1 
ATOM   3101 C  CA  . PHE A 1 416 ? 0.887   2.239   48.301  1   20.803 ? 408  PHE A CA  1 
ATOM   3102 C  C   . PHE A 1 416 ? -0.224  2.696   47.366  1   21.694 ? 408  PHE A C   1 
ATOM   3103 O  O   . PHE A 1 416 ? -1.071  1.887   47.014  1   23.03  ? 408  PHE A O   1 
ATOM   3104 C  CB  . PHE A 1 416 ? 1.704   1.116   47.642  1   22.529 ? 408  PHE A CB  1 
ATOM   3105 C  CG  . PHE A 1 416 ? 2.688   0.491   48.62   1   21.842 ? 408  PHE A CG  1 
ATOM   3106 C  CD1 . PHE A 1 416 ? 3.87    1.167   48.937  1   25.518 ? 408  PHE A CD1 1 
ATOM   3107 C  CD2 . PHE A 1 416 ? 2.384   -0.72   49.262  1   23.562 ? 408  PHE A CD2 1 
ATOM   3108 C  CE1 . PHE A 1 416 ? 4.779   0.624   49.842  1   25.885 ? 408  PHE A CE1 1 
ATOM   3109 C  CE2 . PHE A 1 416 ? 3.276   -1.256  50.188  1   26.566 ? 408  PHE A CE2 1 
ATOM   3110 C  CZ  . PHE A 1 416 ? 4.468   -0.581  50.466  1   26.62  ? 408  PHE A CZ  1 
ATOM   3111 N  N   . ILE A 1 417 ? -0.24   3.989   47.043  1   21.553 ? 409  ILE A N   1 
ATOM   3112 C  CA  . ILE A 1 417 ? -1.445  4.611   46.51   1   20.483 ? 409  ILE A CA  1 
ATOM   3113 C  C   . ILE A 1 417 ? -1.041  5.346   45.238  1   22.029 ? 409  ILE A C   1 
ATOM   3114 O  O   . ILE A 1 417 ? -0.017  6.033   45.189  1   22.537 ? 409  ILE A O   1 
ATOM   3115 C  CB  . ILE A 1 417 ? -2.071  5.558   47.563  1   22.772 ? 409  ILE A CB  1 
ATOM   3116 C  CG1 . ILE A 1 417 ? -2.256  4.843   48.922  1   22.975 ? 409  ILE A CG1 1 
ATOM   3117 C  CG2 . ILE A 1 417 ? -3.409  6.098   47.029  1   22.877 ? 409  ILE A CG2 1 
ATOM   3118 C  CD1 . ILE A 1 417 ? -2.641  5.746   50.086  1   26.527 ? 409  ILE A CD1 1 
ATOM   3119 N  N   . ASN A 1 418 ? -1.86   5.169   44.194  1   22.885 ? 410  ASN A N   1 
ATOM   3120 C  CA  . ASN A 1 418 ? -1.678  5.922   42.961  1   21.047 ? 410  ASN A CA  1 
ATOM   3121 C  C   . ASN A 1 418 ? -2.328  7.292   43.204  1   22.186 ? 410  ASN A C   1 
ATOM   3122 O  O   . ASN A 1 418 ? -3.478  7.372   43.65   1   22.463 ? 410  ASN A O   1 
ATOM   3123 C  CB  . ASN A 1 418 ? -2.387  5.139   41.858  1   21.577 ? 410  ASN A CB  1 
ATOM   3124 C  CG  . ASN A 1 418 ? -1.891  5.36    40.441  1   21.875 ? 410  ASN A CG  1 
ATOM   3125 O  OD1 . ASN A 1 418 ? -0.909  6.074   40.161  1   25.672 ? 410  ASN A OD1 1 
ATOM   3126 N  ND2 . ASN A 1 418 ? -2.548  4.658   39.545  1   18.256 ? 410  ASN A ND2 1 
ATOM   3127 N  N   . VAL A 1 419 ? -1.619  8.382   42.895  1   22.804 ? 411  VAL A N   1 
ATOM   3128 C  CA  . VAL A 1 419 ? -2.054  9.717   43.323  1   23.485 ? 411  VAL A CA  1 
ATOM   3129 C  C   . VAL A 1 419 ? -1.845  10.766  42.226  1   24.744 ? 411  VAL A C   1 
ATOM   3130 O  O   . VAL A 1 419 ? -0.99   10.637  41.335  1   23.344 ? 411  VAL A O   1 
ATOM   3131 C  CB  . VAL A 1 419 ? -1.343  10.184  44.62   1   24.663 ? 411  VAL A CB  1 
ATOM   3132 C  CG1 . VAL A 1 419 ? -1.761  9.348   45.826  1   22.073 ? 411  VAL A CG1 1 
ATOM   3133 C  CG2 . VAL A 1 419 ? 0.178   10.253  44.452  1   23.503 ? 411  VAL A CG2 1 
ATOM   3134 N  N   . PHE A 1 420 ? -2.696  11.803  42.285  1   24.17  ? 412  PHE A N   1 
ATOM   3135 C  CA  . PHE A 1 420 ? -2.387  13.096  41.685  1   22.372 ? 412  PHE A CA  1 
ATOM   3136 C  C   . PHE A 1 420 ? -1.402  13.762  42.635  1   25.275 ? 412  PHE A C   1 
ATOM   3137 O  O   . PHE A 1 420 ? -1.739  14.002  43.811  1   24.793 ? 412  PHE A O   1 
ATOM   3138 C  CB  . PHE A 1 420 ? -3.657  13.955  41.574  1   23.708 ? 412  PHE A CB  1 
ATOM   3139 C  CG  . PHE A 1 420 ? -4.707  13.603  40.514  1   23.652 ? 412  PHE A CG  1 
ATOM   3140 C  CD1 . PHE A 1 420 ? -5.059  12.266  40.226  1   23.188 ? 412  PHE A CD1 1 
ATOM   3141 C  CD2 . PHE A 1 420 ? -5.388  14.626  39.839  1   22.465 ? 412  PHE A CD2 1 
ATOM   3142 C  CE1 . PHE A 1 420 ? -6.081  11.982  39.3    1   23.264 ? 412  PHE A CE1 1 
ATOM   3143 C  CE2 . PHE A 1 420 ? -6.394  14.342  38.916  1   25.748 ? 412  PHE A CE2 1 
ATOM   3144 C  CZ  . PHE A 1 420 ? -6.752  13.013  38.647  1   23.9   ? 412  PHE A CZ  1 
ATOM   3145 N  N   . VAL A 1 421 ? -0.189  14.037  42.156  1   25.032 ? 413  VAL A N   1 
ATOM   3146 C  CA  . VAL A 1 421 ? 0.832   14.584  43.038  1   26.037 ? 413  VAL A CA  1 
ATOM   3147 C  C   . VAL A 1 421 ? 0.438   16.014  43.445  1   27.212 ? 413  VAL A C   1 
ATOM   3148 O  O   . VAL A 1 421 ? 0.188   16.844  42.575  1   26.004 ? 413  VAL A O   1 
ATOM   3149 C  CB  . VAL A 1 421 ? 2.269   14.5    42.467  1   28.338 ? 413  VAL A CB  1 
ATOM   3150 C  CG1 . VAL A 1 421 ? 3.291   15.13   43.431  1   30.086 ? 413  VAL A CG1 1 
ATOM   3151 C  CG2 . VAL A 1 421 ? 2.683   13.054  42.18   1   25.585 ? 413  VAL A CG2 1 
ATOM   3152 N  N   . PRO A 1 422 ? 0.337   16.34   44.763  1   29.297 ? 414  PRO A N   1 
ATOM   3153 C  CA  . PRO A 1 422 ? 0.011   17.698  45.203  1   32.482 ? 414  PRO A CA  1 
ATOM   3154 C  C   . PRO A 1 422 ? 0.907   18.736  44.542  1   31.56  ? 414  PRO A C   1 
ATOM   3155 O  O   . PRO A 1 422 ? 2.126   18.526  44.46   1   33.993 ? 414  PRO A O   1 
ATOM   3156 C  CB  . PRO A 1 422 ? 0.143   17.647  46.74   1   31.486 ? 414  PRO A CB  1 
ATOM   3157 C  CG  . PRO A 1 422 ? -0.092  16.188  47.046  1   28.623 ? 414  PRO A CG  1 
ATOM   3158 C  CD  . PRO A 1 422 ? 0.487   15.417  45.901  1   26.994 ? 414  PRO A CD  1 
ATOM   3159 N  N   . ASP A 1 423 ? 0.268   19.752  43.936  1   37.339 ? 415  ASP A N   1 
ATOM   3160 C  CA  . ASP A 1 423 ? 0.921   20.919  43.334  1   41.264 ? 415  ASP A CA  1 
ATOM   3161 C  C   . ASP A 1 423 ? 1.688   20.575  42.052  1   45.747 ? 415  ASP A C   1 
ATOM   3162 O  O   . ASP A 1 423 ? 2.491   21.384  41.58   1   39.51  ? 415  ASP A O   1 
ATOM   3163 C  CB  . ASP A 1 423 ? 1.761   21.696  44.346  1   44.969 ? 415  ASP A CB  1 
ATOM   3164 C  CG  . ASP A 1 423 ? 0.998   22.201  45.561  1   55.551 ? 415  ASP A CG  1 
ATOM   3165 O  OD1 . ASP A 1 423 ? -0.025  22.886  45.353  1   62.047 ? 415  ASP A OD1 1 
ATOM   3166 O  OD2 . ASP A 1 423 ? 1.407   21.885  46.703  1   63.748 ? 415  ASP A OD2 1 
ATOM   3167 N  N   . ARG A 1 424 ? 1.486   19.358  41.512  1   37.639 ? 416  ARG A N   1 
ATOM   3168 C  CA  . ARG A 1 424 ? 2.173   18.929  40.305  1   36.12  ? 416  ARG A CA  1 
ATOM   3169 C  C   . ARG A 1 424 ? 1.226   18.035  39.499  1   37.755 ? 416  ARG A C   1 
ATOM   3170 O  O   . ARG A 1 424 ? 1.659   17.029  38.956  1   41.152 ? 416  ARG A O   1 
ATOM   3171 C  CB  . ARG A 1 424 ? 3.492   18.193  40.599  1   40.997 ? 416  ARG A CB  1 
ATOM   3172 C  CG  . ARG A 1 424 ? 4.443   18.676  41.685  1   50.637 ? 416  ARG A CG  1 
ATOM   3173 C  CD  . ARG A 1 424 ? 5.699   17.826  41.732  1   56.288 ? 416  ARG A CD  1 
ATOM   3174 N  NE  . ARG A 1 424 ? 6.586   18.048  40.579  1   49.814 ? 416  ARG A NE  1 
ATOM   3175 C  CZ  . ARG A 1 424 ? 7.834   17.578  40.531  1   52.489 ? 416  ARG A CZ  1 
ATOM   3176 N  NH1 . ARG A 1 424 ? 8.605   17.832  39.483  1   48.575 ? 416  ARG A NH1 1 
ATOM   3177 N  NH2 . ARG A 1 424 ? 8.317   16.882  41.558  1   53.172 ? 416  ARG A NH2 1 
ATOM   3178 N  N   . SER A 1 425 ? -0.061  18.408  39.447  1   32.161 ? 417  SER A N   1 
ATOM   3179 C  CA  . SER A 1 425 ? -1.087  17.609  38.78   1   31.217 ? 417  SER A CA  1 
ATOM   3180 C  C   . SER A 1 425 ? -2.264  18.521  38.485  1   33.242 ? 417  SER A C   1 
ATOM   3181 O  O   . SER A 1 425 ? -2.391  19.587  39.074  1   35.07  ? 417  SER A O   1 
ATOM   3182 C  CB  . SER A 1 425 ? -1.542  16.424  39.658  1   30.45  ? 417  SER A CB  1 
ATOM   3183 O  OG  . SER A 1 425 ? -2.007  16.837  40.938  1   31.519 ? 417  SER A OG  1 
ATOM   3184 N  N   . ASP A 1 426 ? -3.175  18.063  37.638  1   32.593 ? 418  ASP A N   1 
ATOM   3185 C  CA  . ASP A 1 426 ? -4.179  18.973  37.141  1   37.448 ? 418  ASP A CA  1 
ATOM   3186 C  C   . ASP A 1 426 ? -5.212  19.319  38.239  1   51.34  ? 418  ASP A C   1 
ATOM   3187 O  O   . ASP A 1 426 ? -5.24   20.455  38.731  1   76.066 ? 418  ASP A O   1 
ATOM   3188 C  CB  . ASP A 1 426 ? -4.41   18.73   35.657  1   36.699 ? 418  ASP A CB  1 
ATOM   3189 C  CG  . ASP A 1 426 ? -5.59   19.477  35.064  1   34.71  ? 418  ASP A CG  1 
ATOM   3190 O  OD1 . ASP A 1 426 ? -6.429  19.988  35.849  1   33.603 ? 418  ASP A OD1 1 
ATOM   3191 O  OD2 . ASP A 1 426 ? -5.68   19.501  33.832  1   39.258 ? 418  ASP A OD2 1 
ATOM   3192 N  N   . GLY A 1 427 ? -6.025  18.338  38.644  1   37.215 ? 419  GLY A N   1 
ATOM   3193 C  CA  . GLY A 1 427 ? -7.142  18.421  39.575  1   30.065 ? 419  GLY A CA  1 
ATOM   3194 C  C   . GLY A 1 427 ? -8.501  18.335  38.861  1   28.825 ? 419  GLY A C   1 
ATOM   3195 O  O   . GLY A 1 427 ? -9.477  17.759  39.384  1   28.131 ? 419  GLY A O   1 
ATOM   3196 N  N   . ASN A 1 428 ? -8.569  18.942  37.667  1   26.554 ? 420  ASN A N   1 
ATOM   3197 C  CA  . ASN A 1 428 ? -9.782  18.911  36.854  1   29.593 ? 420  ASN A CA  1 
ATOM   3198 C  C   . ASN A 1 428 ? -9.889  17.652  35.999  1   25.463 ? 420  ASN A C   1 
ATOM   3199 O  O   . ASN A 1 428 ? -10.937 17.436  35.417  1   24.878 ? 420  ASN A O   1 
ATOM   3200 C  CB  . ASN A 1 428 ? -10.079 20.175  36.049  1   36.71  ? 420  ASN A CB  1 
ATOM   3201 C  CG  . ASN A 1 428 ? -10.825 21.17   36.922  1   41.379 ? 420  ASN A CG  1 
ATOM   3202 O  OD1 . ASN A 1 428 ? -10.3   22.267  37.123  1   38.597 ? 420  ASN A OD1 1 
ATOM   3203 N  ND2 . ASN A 1 428 ? -11.979 20.818  37.508  1   34.4   ? 420  ASN A ND2 1 
ATOM   3204 N  N   . LYS A 1 429 ? -8.847  16.822  35.977  1   24.429 ? 421  LYS A N   1 
ATOM   3205 C  CA  . LYS A 1 429 ? -8.942  15.509  35.329  1   26.638 ? 421  LYS A CA  1 
ATOM   3206 C  C   . LYS A 1 429 ? -9.747  14.532  36.187  1   24.249 ? 421  LYS A C   1 
ATOM   3207 O  O   . LYS A 1 429 ? -9.686  14.553  37.43   1   23.442 ? 421  LYS A O   1 
ATOM   3208 C  CB  . LYS A 1 429 ? -7.547  14.921  35.099  1   27.601 ? 421  LYS A CB  1 
ATOM   3209 C  CG  . LYS A 1 429 ? -6.695  15.76   34.146  1   30.486 ? 421  LYS A CG  1 
ATOM   3210 C  CD  . LYS A 1 429 ? -6.214  15.169  32.825  1   43.198 ? 421  LYS A CD  1 
ATOM   3211 C  CE  . LYS A 1 429 ? -5.157  16.125  32.311  1   48.12  ? 421  LYS A CE  1 
ATOM   3212 N  NZ  . LYS A 1 429 ? -3.876  15.511  31.93   1   49.921 ? 421  LYS A NZ  1 
ATOM   3213 N  N   . ASN A 1 430 ? -10.577 13.724  35.502  1   23.945 ? 422  ASN A N   1 
ATOM   3214 C  CA  . ASN A 1 430 ? -11.2   12.533  36.077  1   23.267 ? 422  ASN A CA  1 
ATOM   3215 C  C   . ASN A 1 430 ? -10.129 11.732  36.819  1   22.853 ? 422  ASN A C   1 
ATOM   3216 O  O   . ASN A 1 430 ? -8.954  11.718  36.413  1   23.626 ? 422  ASN A O   1 
ATOM   3217 C  CB  . ASN A 1 430 ? -11.881 11.748  34.96   1   23.834 ? 422  ASN A CB  1 
ATOM   3218 C  CG  . ASN A 1 430 ? -12.394 10.406  35.413  1   23.134 ? 422  ASN A CG  1 
ATOM   3219 O  OD1 . ASN A 1 430 ? -11.653 9.417   35.348  1   21.369 ? 422  ASN A OD1 1 
ATOM   3220 N  ND2 . ASN A 1 430 ? -13.646 10.371  35.851  1   24.067 ? 422  ASN A ND2 1 
ATOM   3221 N  N   . VAL A 1 431 ? -10.523 11.124  37.95   1   20.83  ? 423  VAL A N   1 
ATOM   3222 C  CA  . VAL A 1 431 ? -9.617  10.504  38.912  1   21.734 ? 423  VAL A CA  1 
ATOM   3223 C  C   . VAL A 1 431 ? -8.734  9.449   38.244  1   19.937 ? 423  VAL A C   1 
ATOM   3224 O  O   . VAL A 1 431 ? -7.623  9.218   38.694  1   21.546 ? 423  VAL A O   1 
ATOM   3225 C  CB  . VAL A 1 431 ? -10.356 9.902   40.133  1   21.121 ? 423  VAL A CB  1 
ATOM   3226 C  CG1 . VAL A 1 431 ? -11.245 8.684   39.808  1   20.922 ? 423  VAL A CG1 1 
ATOM   3227 C  CG2 . VAL A 1 431 ? -9.415  9.579   41.301  1   20.385 ? 423  VAL A CG2 1 
ATOM   3228 N  N   . PHE A 1 432 ? -9.215  8.815   37.16   1   19.236 ? 424  PHE A N   1 
ATOM   3229 C  CA  . PHE A 1 432 ? -8.41   7.752   36.541  1   19.46  ? 424  PHE A CA  1 
ATOM   3230 C  C   . PHE A 1 432 ? -7.425  8.307   35.508  1   20.625 ? 424  PHE A C   1 
ATOM   3231 O  O   . PHE A 1 432 ? -6.613  7.544   34.97   1   22.587 ? 424  PHE A O   1 
ATOM   3232 C  CB  . PHE A 1 432 ? -9.338  6.739   35.853  1   20.082 ? 424  PHE A CB  1 
ATOM   3233 C  CG  . PHE A 1 432 ? -10.178 5.983   36.869  1   21.775 ? 424  PHE A CG  1 
ATOM   3234 C  CD1 . PHE A 1 432 ? -9.59   5.008   37.7    1   23.248 ? 424  PHE A CD1 1 
ATOM   3235 C  CD2 . PHE A 1 432 ? -11.555 6.249   36.965  1   21.317 ? 424  PHE A CD2 1 
ATOM   3236 C  CE1 . PHE A 1 432 ? -10.365 4.332   38.648  1   27.089 ? 424  PHE A CE1 1 
ATOM   3237 C  CE2 . PHE A 1 432 ? -12.32  5.567   37.891  1   24.632 ? 424  PHE A CE2 1 
ATOM   3238 C  CZ  . PHE A 1 432 ? -11.73  4.61    38.725  1   25.764 ? 424  PHE A CZ  1 
ATOM   3239 N  N   . GLN A 1 433 ? -7.499  9.614   35.228  1   20.859 ? 425  GLN A N   1 
ATOM   3240 C  CA  . GLN A 1 433 ? -6.87   10.189  34.043  1   22.396 ? 425  GLN A CA  1 
ATOM   3241 C  C   . GLN A 1 433 ? -5.719  11.13   34.408  1   22.467 ? 425  GLN A C   1 
ATOM   3242 O  O   . GLN A 1 433 ? -5.04   11.615  33.513  1   23.476 ? 425  GLN A O   1 
ATOM   3243 C  CB  . GLN A 1 433 ? -7.87   10.895  33.128  1   21.423 ? 425  GLN A CB  1 
ATOM   3244 C  CG  . GLN A 1 433 ? -9.025  9.977   32.735  1   23.646 ? 425  GLN A CG  1 
ATOM   3245 C  CD  . GLN A 1 433 ? -9.881  10.543  31.638  1   28.48  ? 425  GLN A CD  1 
ATOM   3246 O  OE1 . GLN A 1 433 ? -9.752  11.703  31.269  1   29.639 ? 425  GLN A OE1 1 
ATOM   3247 N  NE2 . GLN A 1 433 ? -10.708 9.706   31.024  1   29.863 ? 425  GLN A NE2 1 
ATOM   3248 N  N   . GLY A 1 434 ? -5.473  11.379  35.701  1   21.147 ? 426  GLY A N   1 
ATOM   3249 C  CA  . GLY A 1 434 ? -4.435  12.342  36.044  1   21.153 ? 426  GLY A CA  1 
ATOM   3250 C  C   . GLY A 1 434 ? -3.429  11.794  37.048  1   23.963 ? 426  GLY A C   1 
ATOM   3251 O  O   . GLY A 1 434 ? -2.724  12.57   37.718  1   23.048 ? 426  GLY A O   1 
ATOM   3252 N  N   . LEU A 1 435 ? -3.381  10.461  37.166  1   21.833 ? 427  LEU A N   1 
ATOM   3253 C  CA  . LEU A 1 435 ? -2.582  9.796   38.203  1   21.53  ? 427  LEU A CA  1 
ATOM   3254 C  C   . LEU A 1 435 ? -1.125  9.796   37.761  1   22.294 ? 427  LEU A C   1 
ATOM   3255 O  O   . LEU A 1 435 ? -0.717  9.016   36.876  1   23.763 ? 427  LEU A O   1 
ATOM   3256 C  CB  . LEU A 1 435 ? -3.096  8.363   38.453  1   20.776 ? 427  LEU A CB  1 
ATOM   3257 C  CG  . LEU A 1 435 ? -4.532  8.268   38.949  1   21.22  ? 427  LEU A CG  1 
ATOM   3258 C  CD1 . LEU A 1 435 ? -5.213  6.886   38.711  1   20.566 ? 427  LEU A CD1 1 
ATOM   3259 C  CD2 . LEU A 1 435 ? -4.591  8.581   40.479  1   20.772 ? 427  LEU A CD2 1 
ATOM   3260 N  N   . ASN A 1 436 ? -0.326  10.678  38.397  1   21.829 ? 428  ASN A N   1 
ATOM   3261 C  CA  . ASN A 1 436 ? 1.04    10.89   37.944  1   21.371 ? 428  ASN A CA  1 
ATOM   3262 C  C   . ASN A 1 436 ? 2.034   10.702  39.089  1   22.954 ? 428  ASN A C   1 
ATOM   3263 O  O   . ASN A 1 436 ? 3.185   11.097  38.968  1   25.142 ? 428  ASN A O   1 
ATOM   3264 C  CB  . ASN A 1 436 ? 1.203   12.266  37.274  1   23.805 ? 428  ASN A CB  1 
ATOM   3265 C  CG  . ASN A 1 436 ? 0.994   13.438  38.218  1   26.269 ? 428  ASN A CG  1 
ATOM   3266 O  OD1 . ASN A 1 436 ? 0.48    13.306  39.341  1   28.221 ? 428  ASN A OD1 1 
ATOM   3267 N  ND2 . ASN A 1 436 ? 1.377   14.62   37.763  1   29.624 ? 428  ASN A ND2 1 
ATOM   3268 N  N   . GLY A 1 437 ? 1.603   10.075  40.171  1   21.992 ? 429  GLY A N   1 
ATOM   3269 C  CA  . GLY A 1 437 ? 2.547   9.777   41.232  1   22.074 ? 429  GLY A CA  1 
ATOM   3270 C  C   . GLY A 1 437 ? 2.111   8.57    42.048  1   24.48  ? 429  GLY A C   1 
ATOM   3271 O  O   . GLY A 1 437 ? 1.032   8.001   41.821  1   22.876 ? 429  GLY A O   1 
ATOM   3272 N  N   . LEU A 1 438 ? 3.003   8.191   42.984  1   24.097 ? 430  LEU A N   1 
ATOM   3273 C  CA  . LEU A 1 438 ? 2.692   7.198   43.995  1   24.542 ? 430  LEU A CA  1 
ATOM   3274 C  C   . LEU A 1 438 ? 2.897   7.812   45.366  1   25.373 ? 430  LEU A C   1 
ATOM   3275 O  O   . LEU A 1 438 ? 3.793   8.646   45.54   1   25.747 ? 430  LEU A O   1 
ATOM   3276 C  CB  . LEU A 1 438 ? 3.592   5.966   43.87   1   23.864 ? 430  LEU A CB  1 
ATOM   3277 C  CG  . LEU A 1 438 ? 3.636   5.33    42.469  1   21.027 ? 430  LEU A CG  1 
ATOM   3278 C  CD1 . LEU A 1 438 ? 4.729   4.273   42.574  1   20.719 ? 430  LEU A CD1 1 
ATOM   3279 C  CD2 . LEU A 1 438 ? 2.262   4.701   42.131  1   23.529 ? 430  LEU A CD2 1 
ATOM   3280 N  N   . ALA A 1 439 ? 2.122   7.316   46.322  1   21.394 ? 431  ALA A N   1 
ATOM   3281 C  CA  . ALA A 1 439 ? 2.337   7.662   47.723  1   23.771 ? 431  ALA A CA  1 
ATOM   3282 C  C   . ALA A 1 439 ? 2.589   6.39    48.513  1   24.464 ? 431  ALA A C   1 
ATOM   3283 O  O   . ALA A 1 439 ? 1.891   5.39    48.318  1   23.466 ? 431  ALA A O   1 
ATOM   3284 C  CB  . ALA A 1 439 ? 1.117   8.4     48.234  1   23.262 ? 431  ALA A CB  1 
ATOM   3285 N  N   . HIS A 1 440 ? 3.569   6.448   49.436  1   23.098 ? 432  HIS A N   1 
ATOM   3286 C  CA  . HIS A 1 440 ? 3.688   5.437   50.448  1   23.939 ? 432  HIS A CA  1 
ATOM   3287 C  C   . HIS A 1 440 ? 3.228   6.036   51.779  1   26.868 ? 432  HIS A C   1 
ATOM   3288 O  O   . HIS A 1 440 ? 3.969   6.814   52.407  1   25.459 ? 432  HIS A O   1 
ATOM   3289 C  CB  . HIS A 1 440 ? 5.112   4.876   50.537  1   24.137 ? 432  HIS A CB  1 
ATOM   3290 C  CG  . HIS A 1 440 ? 5.229   3.739   51.5    1   25.331 ? 432  HIS A CG  1 
ATOM   3291 N  ND1 . HIS A 1 440 ? 6.463   3.224   51.829  1   23.754 ? 432  HIS A ND1 1 
ATOM   3292 C  CD2 . HIS A 1 440 ? 4.32    2.999   52.195  1   25.088 ? 432  HIS A CD2 1 
ATOM   3293 C  CE1 . HIS A 1 440 ? 6.295   2.209   52.676  1   26.808 ? 432  HIS A CE1 1 
ATOM   3294 N  NE2 . HIS A 1 440 ? 5.004   2.068   52.924  1   26.274 ? 432  HIS A NE2 1 
ATOM   3295 N  N   . TYR A 1 441 ? 2.018   5.639   52.193  1   22.751 ? 433  TYR A N   1 
ATOM   3296 C  CA  . TYR A 1 441 ? 1.418   6.07    53.448  1   21.673 ? 433  TYR A CA  1 
ATOM   3297 C  C   . TYR A 1 441 ? 1.637   4.994   54.498  1   24.87  ? 433  TYR A C   1 
ATOM   3298 O  O   . TYR A 1 441 ? 1.499   3.806   54.22   1   25.311 ? 433  TYR A O   1 
ATOM   3299 C  CB  . TYR A 1 441 ? -0.081  6.339   53.231  1   24.928 ? 433  TYR A CB  1 
ATOM   3300 C  CG  . TYR A 1 441 ? -0.832  6.51    54.549  1   26.066 ? 433  TYR A CG  1 
ATOM   3301 C  CD1 . TYR A 1 441 ? -0.68   7.677   55.306  1   26.217 ? 433  TYR A CD1 1 
ATOM   3302 C  CD2 . TYR A 1 441 ? -1.712  5.531   55.017  1   24.867 ? 433  TYR A CD2 1 
ATOM   3303 C  CE1 . TYR A 1 441 ? -1.354  7.832   56.513  1   26.854 ? 433  TYR A CE1 1 
ATOM   3304 C  CE2 . TYR A 1 441 ? -2.399  5.694   56.218  1   27.37  ? 433  TYR A CE2 1 
ATOM   3305 C  CZ  . TYR A 1 441 ? -2.198  6.845   56.974  1   27.21  ? 433  TYR A CZ  1 
ATOM   3306 O  OH  . TYR A 1 441 ? -2.878  7.004   58.167  1   26.612 ? 433  TYR A OH  1 
ATOM   3307 N  N   . LYS A 1 442 ? 2.044   5.423   55.715  1   26.132 ? 434  LYS A N   1 
ATOM   3308 C  CA  . LYS A 1 442 ? 2.249   4.497   56.814  1   26.904 ? 434  LYS A CA  1 
ATOM   3309 C  C   . LYS A 1 442 ? 1.384   5.008   57.968  1   29.425 ? 434  LYS A C   1 
ATOM   3310 O  O   . LYS A 1 442 ? 1.628   6.11    58.47   1   30.369 ? 434  LYS A O   1 
ATOM   3311 C  CB  . LYS A 1 442 ? 3.737   4.588   57.195  1   32.476 ? 434  LYS A CB  1 
ATOM   3312 C  CG  . LYS A 1 442 ? 4.679   3.825   56.279  1   33.726 ? 434  LYS A CG  1 
ATOM   3313 C  CD  . LYS A 1 442 ? 6.129   3.976   56.723  1   38.15  ? 434  LYS A CD  1 
ATOM   3314 C  CE  . LYS A 1 442 ? 6.936   2.981   55.974  1   43.045 ? 434  LYS A CE  1 
ATOM   3315 N  NZ  . LYS A 1 442 ? 8.361   3.001   56.309  1   44.265 ? 434  LYS A NZ  1 
ATOM   3316 N  N   . ARG A 1 443 ? 0.334   4.246   58.312  1   24.876 ? 435  ARG A N   1 
ATOM   3317 C  CA  . ARG A 1 443 ? -0.61   4.692   59.327  1   24.626 ? 435  ARG A CA  1 
ATOM   3318 C  C   . ARG A 1 443 ? 0.087   4.816   60.69   1   27.154 ? 435  ARG A C   1 
ATOM   3319 O  O   . ARG A 1 443 ? -0.133  5.799   61.382  1   29.483 ? 435  ARG A O   1 
ATOM   3320 C  CB  . ARG A 1 443 ? -1.792  3.727   59.421  1   26.94  ? 435  ARG A CB  1 
ATOM   3321 C  CG  . ARG A 1 443 ? -2.837  4.091   60.469  1   23.919 ? 435  ARG A CG  1 
ATOM   3322 C  CD  . ARG A 1 443 ? -4.01   3.12    60.553  1   23.945 ? 435  ARG A CD  1 
ATOM   3323 N  NE  . ARG A 1 443 ? -3.595  1.716   60.729  1   28.89  ? 435  ARG A NE  1 
ATOM   3324 C  CZ  . ARG A 1 443 ? -3.099  1.183   61.849  1   27.058 ? 435  ARG A CZ  1 
ATOM   3325 N  NH1 . ARG A 1 443 ? -3.175  1.861   63.006  1   27.071 ? 435  ARG A NH1 1 
ATOM   3326 N  NH2 . ARG A 1 443 ? -2.637  -0.05   61.831  1   28.917 ? 435  ARG A NH2 1 
ATOM   3327 N  N   . LYS A 1 444 ? 0.925   3.839   61.035  1   27.729 ? 436  LYS A N   1 
ATOM   3328 C  CA  . LYS A 1 444 ? 1.552   3.763   62.365  1   29.91  ? 436  LYS A CA  1 
ATOM   3329 C  C   . LYS A 1 444 ? 2.49    4.951   62.606  1   32.487 ? 436  LYS A C   1 
ATOM   3330 O  O   . LYS A 1 444 ? 2.44    5.542   63.683  1   37.089 ? 436  LYS A O   1 
ATOM   3331 C  CB  . LYS A 1 444 ? 2.199   2.396   62.603  1   30.569 ? 436  LYS A CB  1 
ATOM   3332 C  CG  . LYS A 1 444 ? 1.198   1.286   62.943  1   31.873 ? 436  LYS A CG  1 
ATOM   3333 C  CD  . LYS A 1 444 ? 1.863   -0.093  62.902  1   35.853 ? 436  LYS A CD  1 
ATOM   3334 C  CE  . LYS A 1 444 ? 0.881   -1.135  63.387  1   37.569 ? 436  LYS A CE  1 
ATOM   3335 N  NZ  . LYS A 1 444 ? 1.348   -2.524  63.264  1   41.04  ? 436  LYS A NZ  1 
ATOM   3336 N  N   . GLU A 1 445 ? 3.278   5.346   61.591  1   35.109 ? 437  GLU A N   1 
ATOM   3337 C  CA  . GLU A 1 445 ? 4.188   6.497   61.668  1   34.856 ? 437  GLU A CA  1 
ATOM   3338 C  C   . GLU A 1 445 ? 3.458   7.798   61.333  1   36.536 ? 437  GLU A C   1 
ATOM   3339 O  O   . GLU A 1 445 ? 3.96    8.867   61.65   1   38.075 ? 437  GLU A O   1 
ATOM   3340 C  CB  . GLU A 1 445 ? 5.44    6.367   60.794  1   40.757 ? 437  GLU A CB  1 
ATOM   3341 C  CG  . GLU A 1 445 ? 6.378   5.236   61.211  1   40.322 ? 437  GLU A CG  1 
ATOM   3342 C  CD  . GLU A 1 445 ? 5.989   3.8     60.866  1   50.982 ? 437  GLU A CD  1 
ATOM   3343 O  OE1 . GLU A 1 445 ? 4.92    3.545   60.244  1   48.274 ? 437  GLU A OE1 1 
ATOM   3344 O  OE2 . GLU A 1 445 ? 6.778   2.903   61.233  1   53.81  ? 437  GLU A OE2 1 
ATOM   3345 N  N   . GLY A 1 446 ? 2.288   7.717   60.683  1   29.226 ? 438  GLY A N   1 
ATOM   3346 C  CA  . GLY A 1 446 ? 1.541   8.884   60.243  1   31.692 ? 438  GLY A CA  1 
ATOM   3347 C  C   . GLY A 1 446 ? 2.27    9.667   59.145  1   40.693 ? 438  GLY A C   1 
ATOM   3348 O  O   . GLY A 1 446 ? 2.043   10.873  59.005  1   44.253 ? 438  GLY A O   1 
ATOM   3349 N  N   . THR A 1 447 ? 3.137   8.988   58.374  1   36.151 ? 439  THR A N   1 
ATOM   3350 C  CA  . THR A 1 447 ? 3.933   9.633   57.329  1   31.044 ? 439  THR A CA  1 
ATOM   3351 C  C   . THR A 1 447 ? 3.385   9.284   55.94   1   30.508 ? 439  THR A C   1 
ATOM   3352 O  O   . THR A 1 447 ? 2.878   8.179   55.745  1   29.635 ? 439  THR A O   1 
ATOM   3353 C  CB  . THR A 1 447 ? 5.41    9.262   57.433  1   33.035 ? 439  THR A CB  1 
ATOM   3354 O  OG1 . THR A 1 447 ? 5.492   7.842   57.318  1   34.034 ? 439  THR A OG1 1 
ATOM   3355 C  CG2 . THR A 1 447 ? 6.078   9.766   58.706  1   39.163 ? 439  THR A CG2 1 
ATOM   3356 N  N   . THR A 1 448 ? 3.598   10.188  54.984  1   26.091 ? 440  THR A N   1 
ATOM   3357 C  CA  . THR A 1 448 ? 3.445   9.903   53.553  1   28.728 ? 440  THR A CA  1 
ATOM   3358 C  C   . THR A 1 448 ? 4.704   10.328  52.784  1   33.078 ? 440  THR A C   1 
ATOM   3359 O  O   . THR A 1 448 ? 5.187   11.45   52.944  1   32.869 ? 440  THR A O   1 
ATOM   3360 C  CB  . THR A 1 448 ? 2.197   10.583  52.991  1   27.531 ? 440  THR A CB  1 
ATOM   3361 O  OG1 . THR A 1 448 ? 1.106   10.276  53.849  1   25.892 ? 440  THR A OG1 1 
ATOM   3362 C  CG2 . THR A 1 448 ? 1.826   10.058  51.61   1   28.184 ? 440  THR A CG2 1 
ATOM   3363 N  N   . GLU A 1 449 ? 5.222   9.432   51.927  1   26.096 ? 441  GLU A N   1 
ATOM   3364 C  CA  . GLU A 1 449 ? 6.308   9.718   51.006  1   26.415 ? 441  GLU A CA  1 
ATOM   3365 C  C   . GLU A 1 449 ? 5.766   9.643   49.576  1   29     ? 441  GLU A C   1 
ATOM   3366 O  O   . GLU A 1 449 ? 4.769   8.974   49.334  1   28.14  ? 441  GLU A O   1 
ATOM   3367 C  CB  . GLU A 1 449 ? 7.416   8.705   51.257  1   26.824 ? 441  GLU A CB  1 
ATOM   3368 C  CG  . GLU A 1 449 ? 8.016   8.887   52.655  1   29.141 ? 441  GLU A CG  1 
ATOM   3369 C  CD  . GLU A 1 449 ? 8.839   7.661   52.951  1   34.443 ? 441  GLU A CD  1 
ATOM   3370 O  OE1 . GLU A 1 449 ? 10.002  7.778   52.546  1   36.254 ? 441  GLU A OE1 1 
ATOM   3371 O  OE2 . GLU A 1 449 ? 8.364   6.638   53.499  1   36.51  ? 441  GLU A OE2 1 
ATOM   3372 N  N   . TRP A 1 450 ? 6.415   10.371  48.657  1   26.964 ? 442  TRP A N   1 
ATOM   3373 C  CA  . TRP A 1 450 ? 5.824   10.648  47.352  1   27.56  ? 442  TRP A CA  1 
ATOM   3374 C  C   . TRP A 1 450 ? 6.832   10.323  46.257  1   29.797 ? 442  TRP A C   1 
ATOM   3375 O  O   . TRP A 1 450 ? 8.015   10.662  46.37   1   28.555 ? 442  TRP A O   1 
ATOM   3376 C  CB  . TRP A 1 450 ? 5.369   12.123  47.258  1   25.755 ? 442  TRP A CB  1 
ATOM   3377 C  CG  . TRP A 1 450 ? 4.404   12.535  48.35   1   27.848 ? 442  TRP A CG  1 
ATOM   3378 C  CD1 . TRP A 1 450 ? 4.71    12.926  49.63   1   29.3   ? 442  TRP A CD1 1 
ATOM   3379 C  CD2 . TRP A 1 450 ? 2.961   12.546  48.273  1   28.392 ? 442  TRP A CD2 1 
ATOM   3380 N  NE1 . TRP A 1 450 ? 3.573   13.215  50.341  1   27.831 ? 442  TRP A NE1 1 
ATOM   3381 C  CE2 . TRP A 1 450 ? 2.482   12.976  49.54   1   28.848 ? 442  TRP A CE2 1 
ATOM   3382 C  CE3 . TRP A 1 450 ? 2.02    12.237  47.27   1   28.085 ? 442  TRP A CE3 1 
ATOM   3383 C  CZ2 . TRP A 1 450 ? 1.123   13.11   49.819  1   25.407 ? 442  TRP A CZ2 1 
ATOM   3384 C  CZ3 . TRP A 1 450 ? 0.676   12.364  47.562  1   27.377 ? 442  TRP A CZ3 1 
ATOM   3385 C  CH2 . TRP A 1 450 ? 0.223   12.808  48.817  1   29.892 ? 442  TRP A CH2 1 
ATOM   3386 N  N   . TYR A 1 451 ? 6.328   9.671   45.202  1   25.932 ? 443  TYR A N   1 
ATOM   3387 C  CA  . TYR A 1 451 ? 7.086   9.409   43.985  1   25.356 ? 443  TYR A CA  1 
ATOM   3388 C  C   . TYR A 1 451 ? 6.386   10.147  42.848  1   26.262 ? 443  TYR A C   1 
ATOM   3389 O  O   . TYR A 1 451 ? 5.175   9.967   42.651  1   25.439 ? 443  TYR A O   1 
ATOM   3390 C  CB  . TYR A 1 451 ? 7.212   7.896   43.695  1   23.384 ? 443  TYR A CB  1 
ATOM   3391 C  CG  . TYR A 1 451 ? 7.992   7.694   42.395  1   24.861 ? 443  TYR A CG  1 
ATOM   3392 C  CD1 . TYR A 1 451 ? 9.405   7.799   42.345  1   21.24  ? 443  TYR A CD1 1 
ATOM   3393 C  CD2 . TYR A 1 451 ? 7.311   7.456   41.2    1   23.936 ? 443  TYR A CD2 1 
ATOM   3394 C  CE1 . TYR A 1 451 ? 10.097  7.636   41.149  1   23.615 ? 443  TYR A CE1 1 
ATOM   3395 C  CE2 . TYR A 1 451 ? 8.008   7.289   40.011  1   22.07  ? 443  TYR A CE2 1 
ATOM   3396 C  CZ  . TYR A 1 451 ? 9.384   7.406   39.975  1   24.782 ? 443  TYR A CZ  1 
ATOM   3397 O  OH  . TYR A 1 451 ? 10.048  7.289   38.779  1   24.536 ? 443  TYR A OH  1 
ATOM   3398 N  N   . TYR A 1 452 ? 7.153   10.965  42.105  1   26.041 ? 444  TYR A N   1 
ATOM   3399 C  CA  . TYR A 1 452 ? 6.62    11.684  40.961  1   25.237 ? 444  TYR A CA  1 
ATOM   3400 C  C   . TYR A 1 452 ? 7.018   10.917  39.698  1   27.522 ? 444  TYR A C   1 
ATOM   3401 O  O   . TYR A 1 452 ? 8.2     10.645  39.508  1   25.516 ? 444  TYR A O   1 
ATOM   3402 C  CB  . TYR A 1 452 ? 7.188   13.112  40.969  1   29.693 ? 444  TYR A CB  1 
ATOM   3403 C  CG  . TYR A 1 452 ? 6.763   13.944  39.769  1   27.12  ? 444  TYR A CG  1 
ATOM   3404 C  CD1 . TYR A 1 452 ? 5.413   14.075  39.422  1   27.642 ? 444  TYR A CD1 1 
ATOM   3405 C  CD2 . TYR A 1 452 ? 7.717   14.544  38.939  1   30.109 ? 444  TYR A CD2 1 
ATOM   3406 C  CE1 . TYR A 1 452 ? 5.028   14.835  38.32   1   28.544 ? 444  TYR A CE1 1 
ATOM   3407 C  CE2 . TYR A 1 452 ? 7.35    15.283  37.824  1   26.972 ? 444  TYR A CE2 1 
ATOM   3408 C  CZ  . TYR A 1 452 ? 6.003   15.452  37.539  1   30.008 ? 444  TYR A CZ  1 
ATOM   3409 O  OH  . TYR A 1 452 ? 5.592   16.152  36.448  1   33.946 ? 444  TYR A OH  1 
ATOM   3410 N  N   . ALA A 1 453 ? 6.028   10.595  38.835  1   24.644 ? 445  ALA A N   1 
ATOM   3411 C  CA  . ALA A 1 453 ? 6.254   9.806   37.616  1   26.766 ? 445  ALA A CA  1 
ATOM   3412 C  C   . ALA A 1 453 ? 7.178   10.528  36.635  1   28.633 ? 445  ALA A C   1 
ATOM   3413 O  O   . ALA A 1 453 ? 7.896   9.874   35.893  1   28.539 ? 445  ALA A O   1 
ATOM   3414 C  CB  . ALA A 1 453 ? 4.952   9.452   36.907  1   25.583 ? 445  ALA A CB  1 
ATOM   3415 N  N   . GLY A 1 454 ? 7.148   11.864  36.641  1   28.847 ? 446  GLY A N   1 
ATOM   3416 C  CA  . GLY A 1 454 ? 7.93    12.647  35.703  1   31.594 ? 446  GLY A CA  1 
ATOM   3417 C  C   . GLY A 1 454 ? 7.003   13.504  34.868  1   29.654 ? 446  GLY A C   1 
ATOM   3418 O  O   . GLY A 1 454 ? 5.784   13.258  34.798  1   29.347 ? 446  GLY A O   1 
ATOM   3419 N  N   . ASP A 1 455 ? 7.588   14.551  34.271  1   29.834 ? 447  ASP A N   1 
ATOM   3420 C  CA  . ASP A 1 455 ? 6.829   15.394  33.363  1   28.198 ? 447  ASP A CA  1 
ATOM   3421 C  C   . ASP A 1 455 ? 6.439   14.566  32.142  1   28.715 ? 447  ASP A C   1 
ATOM   3422 O  O   . ASP A 1 455 ? 7.218   13.716  31.709  1   32.934 ? 447  ASP A O   1 
ATOM   3423 C  CB  . ASP A 1 455 ? 7.675   16.582  32.922  1   32.331 ? 447  ASP A CB  1 
ATOM   3424 C  CG  . ASP A 1 455 ? 7.972   17.641  33.977  1   37.764 ? 447  ASP A CG  1 
ATOM   3425 O  OD1 . ASP A 1 455 ? 7.518   17.502  35.146  1   35.158 ? 447  ASP A OD1 1 
ATOM   3426 O  OD2 . ASP A 1 455 ? 8.649   18.621  33.61   1   42.438 ? 447  ASP A OD2 1 
ATOM   3427 N  N   . ASN A 1 456 ? 5.218   14.788  31.646  1   31.853 ? 448  ASN A N   1 
ATOM   3428 C  CA  . ASN A 1 456 ? 4.67    14.073  30.488  1   37.436 ? 448  ASN A CA  1 
ATOM   3429 C  C   . ASN A 1 456 ? 4.625   12.567  30.765  1   36.341 ? 448  ASN A C   1 
ATOM   3430 O  O   . ASN A 1 456 ? 4.872   11.746  29.872  1   32.302 ? 448  ASN A O   1 
ATOM   3431 C  CB  . ASN A 1 456 ? 5.421   14.384  29.19   1   42.144 ? 448  ASN A CB  1 
ATOM   3432 C  CG  . ASN A 1 456 ? 5.517   15.861  28.919  1   45.022 ? 448  ASN A CG  1 
ATOM   3433 O  OD1 . ASN A 1 456 ? 6.622   16.381  28.744  1   54.581 ? 448  ASN A OD1 1 
ATOM   3434 N  ND2 . ASN A 1 456 ? 4.38    16.535  28.868  1   48.199 ? 448  ASN A ND2 1 
ATOM   3435 N  N   . CYS A 1 457 ? 4.352   12.225  32.036  1   29.25  ? 449  CYS A N   1 
ATOM   3436 C  CA  . CYS A 1 457 ? 4.214   10.843  32.433  1   27.812 ? 449  CYS A CA  1 
ATOM   3437 C  C   . CYS A 1 457 ? 2.953   10.651  33.259  1   29.336 ? 449  CYS A C   1 
ATOM   3438 O  O   . CYS A 1 457 ? 2.508   11.546  34.001  1   30.359 ? 449  CYS A O   1 
ATOM   3439 C  CB  . CYS A 1 457 ? 5.383   10.378  33.287  1   29.86  ? 449  CYS A CB  1 
ATOM   3440 S  SG  . CYS A 1 457 ? 6.975   10.317  32.412  1   31.593 ? 449  CYS A SG  1 
ATOM   3441 N  N   . LEU A 1 458 ? 2.371   9.456   33.078  1   25.928 ? 450  LEU A N   1 
ATOM   3442 C  CA  . LEU A 1 458 ? 1.416   8.908   34.026  1   24.019 ? 450  LEU A CA  1 
ATOM   3443 C  C   . LEU A 1 458 ? 2.007   7.655   34.639  1   23.942 ? 450  LEU A C   1 
ATOM   3444 O  O   . LEU A 1 458 ? 2.942   7.078   34.076  1   26.81  ? 450  LEU A O   1 
ATOM   3445 C  CB  . LEU A 1 458 ? 0.068   8.633   33.344  1   22.963 ? 450  LEU A CB  1 
ATOM   3446 C  CG  . LEU A 1 458 ? -0.665  9.856   32.789  1   26.36  ? 450  LEU A CG  1 
ATOM   3447 C  CD1 . LEU A 1 458 ? -1.906  9.423   31.998  1   27.64  ? 450  LEU A CD1 1 
ATOM   3448 C  CD2 . LEU A 1 458 ? -1.078  10.839  33.878  1   29.609 ? 450  LEU A CD2 1 
ATOM   3449 N  N   . ILE A 1 459 ? 1.496   7.279   35.823  1   21.479 ? 451  ILE A N   1 
ATOM   3450 C  CA  . ILE A 1 459 ? 1.941   6.037   36.454  1   21.427 ? 451  ILE A CA  1 
ATOM   3451 C  C   . ILE A 1 459 ? 0.684   5.293   36.902  1   19.606 ? 451  ILE A C   1 
ATOM   3452 O  O   . ILE A 1 459 ? -0.33   5.919   37.262  1   20.032 ? 451  ILE A O   1 
ATOM   3453 C  CB  . ILE A 1 459 ? 2.961   6.287   37.593  1   22.47  ? 451  ILE A CB  1 
ATOM   3454 C  CG1 . ILE A 1 459 ? 3.642   5.003   38.067  1   21.628 ? 451  ILE A CG1 1 
ATOM   3455 C  CG2 . ILE A 1 459 ? 2.336   7.06    38.767  1   21.305 ? 451  ILE A CG2 1 
ATOM   3456 C  CD1 . ILE A 1 459 ? 4.916   5.269   38.897  1   19.586 ? 451  ILE A CD1 1 
ATOM   3457 N  N   . GLN A 1 460 ? 0.747   3.958   36.85   1   18.909 ? 452  GLN A N   1 
ATOM   3458 C  CA  . GLN A 1 460 ? -0.391  3.1     37.15   1   19.331 ? 452  GLN A CA  1 
ATOM   3459 C  C   . GLN A 1 460 ? -0.224  2.498   38.547  1   19.325 ? 452  GLN A C   1 
ATOM   3460 O  O   . GLN A 1 460 ? 0.689   2.881   39.311  1   21.024 ? 452  GLN A O   1 
ATOM   3461 C  CB  . GLN A 1 460 ? -0.509  2.078   36.018  1   21.487 ? 452  GLN A CB  1 
ATOM   3462 C  CG  . GLN A 1 460 ? -0.9    2.75    34.705  1   20.499 ? 452  GLN A CG  1 
ATOM   3463 C  CD  . GLN A 1 460 ? -0.563  1.875   33.521  1   22.042 ? 452  GLN A CD  1 
ATOM   3464 O  OE1 . GLN A 1 460 ? -0.915  0.683   33.48   1   21.184 ? 452  GLN A OE1 1 
ATOM   3465 N  NE2 . GLN A 1 460 ? 0.09    2.468   32.529  1   19.26  ? 452  GLN A NE2 1 
ATOM   3466 N  N   . GLU A 1 461 ? -1.093  1.535   38.86   1   18.246 ? 453  GLU A N   1 
ATOM   3467 C  CA  . GLU A 1 461 ? -1.182  1.014   40.236  1   18.813 ? 453  GLU A CA  1 
ATOM   3468 C  C   . GLU A 1 461 ? 0.145   0.407   40.696  1   19.212 ? 453  GLU A C   1 
ATOM   3469 O  O   . GLU A 1 461 ? 0.77    -0.368  39.972  1   21.826 ? 453  GLU A O   1 
ATOM   3470 C  CB  . GLU A 1 461 ? -2.269  -0.067  40.25   1   20.137 ? 453  GLU A CB  1 
ATOM   3471 C  CG  . GLU A 1 461 ? -2.376  -0.774  41.602  1   20.622 ? 453  GLU A CG  1 
ATOM   3472 C  CD  . GLU A 1 461 ? -3.258  -1.996  41.463  1   23.837 ? 453  GLU A CD  1 
ATOM   3473 O  OE1 . GLU A 1 461 ? -2.91   -2.818  40.583  1   25.156 ? 453  GLU A OE1 1 
ATOM   3474 O  OE2 . GLU A 1 461 ? -4.265  -2.121  42.236  1   25.584 ? 453  GLU A OE2 1 
ATOM   3475 N  N   . PRO A 1 462 ? 0.585   0.7     41.946  1   18.904 ? 454  PRO A N   1 
ATOM   3476 C  CA  . PRO A 1 462 ? 1.795   0.098   42.476  1   20.265 ? 454  PRO A CA  1 
ATOM   3477 C  C   . PRO A 1 462 ? 1.55    -1.291  43.049  1   19.644 ? 454  PRO A C   1 
ATOM   3478 O  O   . PRO A 1 462 ? 0.446   -1.582  43.515  1   20.783 ? 454  PRO A O   1 
ATOM   3479 C  CB  . PRO A 1 462 ? 2.195   1.071   43.608  1   21.543 ? 454  PRO A CB  1 
ATOM   3480 C  CG  . PRO A 1 462 ? 0.827   1.582   44.091  1   20.585 ? 454  PRO A CG  1 
ATOM   3481 C  CD  . PRO A 1 462 ? -0.027  1.712   42.854  1   19.769 ? 454  PRO A CD  1 
ATOM   3482 N  N   . VAL A 1 463 ? 2.609   -2.095  43.066  1   17.782 ? 455  VAL A N   1 
ATOM   3483 C  CA  . VAL A 1 463 ? 2.626   -3.381  43.745  1   20.816 ? 455  VAL A CA  1 
ATOM   3484 C  C   . VAL A 1 463 ? 3.884   -3.414  44.605  1   23.243 ? 455  VAL A C   1 
ATOM   3485 O  O   . VAL A 1 463 ? 4.864   -2.791  44.22   1   22.069 ? 455  VAL A O   1 
ATOM   3486 C  CB  . VAL A 1 463 ? 2.554   -4.631  42.844  1   19.476 ? 455  VAL A CB  1 
ATOM   3487 C  CG1 . VAL A 1 463 ? 1.25    -4.624  42.023  1   19.563 ? 455  VAL A CG1 1 
ATOM   3488 C  CG2 . VAL A 1 463 ? 3.764   -4.707  41.903  1   19.98  ? 455  VAL A CG2 1 
ATOM   3489 N  N   . PHE A 1 464 ? 3.832   -4.209  45.683  1   23.071 ? 456  PHE A N   1 
ATOM   3490 C  CA  . PHE A 1 464 ? 4.945   -4.254  46.625  1   22.357 ? 456  PHE A CA  1 
ATOM   3491 C  C   . PHE A 1 464 ? 5.506   -5.665  46.727  1   22.778 ? 456  PHE A C   1 
ATOM   3492 O  O   . PHE A 1 464 ? 4.771   -6.656  46.83   1   21.98  ? 456  PHE A O   1 
ATOM   3493 C  CB  . PHE A 1 464 ? 4.404   -3.785  47.987  1   22.355 ? 456  PHE A CB  1 
ATOM   3494 C  CG  . PHE A 1 464 ? 5.403   -4.024  49.11   1   25.497 ? 456  PHE A CG  1 
ATOM   3495 C  CD1 . PHE A 1 464 ? 6.476   -3.155  49.295  1   24.299 ? 456  PHE A CD1 1 
ATOM   3496 C  CD2 . PHE A 1 464 ? 5.257   -5.134  49.951  1   25.034 ? 456  PHE A CD2 1 
ATOM   3497 C  CE1 . PHE A 1 464 ? 7.398   -3.386  50.322  1   26.575 ? 456  PHE A CE1 1 
ATOM   3498 C  CE2 . PHE A 1 464 ? 6.179   -5.363  50.989  1   23.669 ? 456  PHE A CE2 1 
ATOM   3499 C  CZ  . PHE A 1 464 ? 7.228   -4.478  51.171  1   24.847 ? 456  PHE A CZ  1 
ATOM   3500 N  N   . SER A 1 465 ? 6.845   -5.737  46.762  1   20.699 ? 457  SER A N   1 
ATOM   3501 C  CA  . SER A 1 465 ? 7.533   -6.989  47.009  1   21.861 ? 457  SER A CA  1 
ATOM   3502 C  C   . SER A 1 465 ? 8.387   -6.772  48.257  1   23.148 ? 457  SER A C   1 
ATOM   3503 O  O   . SER A 1 465 ? 9.225   -5.883  48.241  1   24.498 ? 457  SER A O   1 
ATOM   3504 C  CB  . SER A 1 465 ? 8.438   -7.349  45.817  1   21.824 ? 457  SER A CB  1 
ATOM   3505 O  OG  . SER A 1 465 ? 9.241   -8.499  46.105  1   23.245 ? 457  SER A OG  1 
ATOM   3506 N  N   . PRO A 1 466 ? 8.241   -7.609  49.307  1   26.007 ? 458  PRO A N   1 
ATOM   3507 C  CA  . PRO A 1 466 ? 9.078   -7.453  50.488  1   26.49  ? 458  PRO A CA  1 
ATOM   3508 C  C   . PRO A 1 466 ? 10.558  -7.71   50.181  1   25.793 ? 458  PRO A C   1 
ATOM   3509 O  O   . PRO A 1 466 ? 10.887  -8.521  49.315  1   26.535 ? 458  PRO A O   1 
ATOM   3510 C  CB  . PRO A 1 466 ? 8.524   -8.483  51.473  1   25.848 ? 458  PRO A CB  1 
ATOM   3511 C  CG  . PRO A 1 466 ? 7.392   -9.231  50.808  1   30.548 ? 458  PRO A CG  1 
ATOM   3512 C  CD  . PRO A 1 466 ? 7.317   -8.769  49.353  1   24.674 ? 458  PRO A CD  1 
ATOM   3513 N  N   . ARG A 1 467 ? 11.462  -7.016  50.881  1   28.498 ? 459  ARG A N   1 
ATOM   3514 C  CA  . ARG A 1 467 ? 12.895  -7.173  50.615  1   28.626 ? 459  ARG A CA  1 
ATOM   3515 C  C   . ARG A 1 467 ? 13.348  -8.625  50.832  1   29.277 ? 459  ARG A C   1 
ATOM   3516 O  O   . ARG A 1 467 ? 14.205  -9.135  50.113  1   27.762 ? 459  ARG A O   1 
ATOM   3517 C  CB  . ARG A 1 467 ? 13.699  -6.227  51.518  1   27.306 ? 459  ARG A CB  1 
ATOM   3518 C  CG  . ARG A 1 467 ? 15.166  -6.06   51.141  1   30.531 ? 459  ARG A CG  1 
ATOM   3519 C  CD  . ARG A 1 467 ? 15.859  -5.071  52.064  1   27.748 ? 459  ARG A CD  1 
ATOM   3520 N  NE  . ARG A 1 467 ? 15.165  -3.781  52.133  1   27.092 ? 459  ARG A NE  1 
ATOM   3521 C  CZ  . ARG A 1 467 ? 15.143  -2.839  51.177  1   29.038 ? 459  ARG A CZ  1 
ATOM   3522 N  NH1 . ARG A 1 467 ? 15.997  -2.87   50.154  1   28.266 ? 459  ARG A NH1 1 
ATOM   3523 N  NH2 . ARG A 1 467 ? 14.299  -1.816  51.293  1   30.576 ? 459  ARG A NH2 1 
ATOM   3524 N  N   . SER A 1 468 ? 12.764  -9.272  51.846  1   30.014 ? 460  SER A N   1 
ATOM   3525 C  CA  . SER A 1 468 ? 12.93   -10.681 52.159  1   33.354 ? 460  SER A CA  1 
ATOM   3526 C  C   . SER A 1 468 ? 11.684  -11.087 52.933  1   30.065 ? 460  SER A C   1 
ATOM   3527 O  O   . SER A 1 468 ? 10.89   -10.223 53.298  1   30.154 ? 460  SER A O   1 
ATOM   3528 C  CB  . SER A 1 468 ? 14.161  -10.899 53.015  1   34.945 ? 460  SER A CB  1 
ATOM   3529 O  OG  . SER A 1 468 ? 13.978  -10.255 54.268  1   35.964 ? 460  SER A OG  1 
ATOM   3530 N  N   . LYS A 1 469 ? 11.53   -12.39  53.184  1   36.461 ? 461  LYS A N   1 
ATOM   3531 C  CA  . LYS A 1 469 ? 10.294  -12.96  53.708  1   45.855 ? 461  LYS A CA  1 
ATOM   3532 C  C   . LYS A 1 469 ? 9.946   -12.336 55.064  1   46.686 ? 461  LYS A C   1 
ATOM   3533 O  O   . LYS A 1 469 ? 8.764   -12.105 55.329  1   39.72  ? 461  LYS A O   1 
ATOM   3534 C  CB  . LYS A 1 469 ? 10.368  -14.49  53.636  1   56.728 ? 461  LYS A CB  1 
ATOM   3535 C  CG  . LYS A 1 469 ? 10.021  -15.004 52.23   1   67.141 ? 461  LYS A CG  1 
ATOM   3536 C  CD  . LYS A 1 469 ? 10.27   -16.471 51.883  1   80.739 ? 461  LYS A CD  1 
ATOM   3537 C  CE  . LYS A 1 469 ? 9.724   -17.549 52.794  1   90.202 ? 461  LYS A CE  1 
ATOM   3538 N  NZ  . LYS A 1 469 ? 8.288   -17.487 53.1    1   81.331 ? 461  LYS A NZ  1 
ATOM   3539 N  N   . ASP A 1 470 ? 10.983  -11.989 55.85   1   40.416 ? 462  ASP A N   1 
ATOM   3540 C  CA  . ASP A 1 470 ? 10.861  -11.453 57.2    1   43.618 ? 462  ASP A CA  1 
ATOM   3541 C  C   . ASP A 1 470 ? 11.246  -9.974  57.265  1   38.724 ? 462  ASP A C   1 
ATOM   3542 O  O   . ASP A 1 470 ? 11.444  -9.444  58.359  1   42.01  ? 462  ASP A O   1 
ATOM   3543 C  CB  . ASP A 1 470 ? 11.705  -12.28  58.162  1   50.7   ? 462  ASP A CB  1 
ATOM   3544 C  CG  . ASP A 1 470 ? 13.21   -12.28  57.9    1   59.252 ? 462  ASP A CG  1 
ATOM   3545 O  OD1 . ASP A 1 470 ? 13.649  -11.907 56.778  1   61.661 ? 462  ASP A OD1 1 
ATOM   3546 O  OD2 . ASP A 1 470 ? 13.946  -12.632 58.832  1   73.714 ? 462  ASP A OD2 1 
ATOM   3547 N  N   . ALA A 1 471 ? 11.331  -9.278  56.114  1   35.252 ? 463  ALA A N   1 
ATOM   3548 C  CA  . ALA A 1 471 ? 11.507  -7.824  56.113  1   29.707 ? 463  ALA A CA  1 
ATOM   3549 C  C   . ALA A 1 471 ? 10.383  -7.159  56.897  1   28.57  ? 463  ALA A C   1 
ATOM   3550 O  O   . ALA A 1 471 ? 9.256   -7.665  56.83   1   33.672 ? 463  ALA A O   1 
ATOM   3551 C  CB  . ALA A 1 471 ? 11.521  -7.287  54.684  1   26.78  ? 463  ALA A CB  1 
ATOM   3552 N  N   . PRO A 1 472 ? 10.597  -6.007  57.594  1   31.362 ? 464  PRO A N   1 
ATOM   3553 C  CA  . PRO A 1 472 ? 9.486   -5.261  58.197  1   32.357 ? 464  PRO A CA  1 
ATOM   3554 C  C   . PRO A 1 472 ? 8.384   -4.939  57.178  1   32.774 ? 464  PRO A C   1 
ATOM   3555 O  O   . PRO A 1 472 ? 8.665   -4.863  55.974  1   29.7   ? 464  PRO A O   1 
ATOM   3556 C  CB  . PRO A 1 472 ? 10.106  -3.925  58.629  1   35.592 ? 464  PRO A CB  1 
ATOM   3557 C  CG  . PRO A 1 472 ? 11.573  -4.276  58.835  1   33.379 ? 464  PRO A CG  1 
ATOM   3558 C  CD  . PRO A 1 472 ? 11.896  -5.336  57.812  1   30.863 ? 464  PRO A CD  1 
ATOM   3559 N  N   . GLU A 1 473 ? 7.16    -4.712  57.673  1   31.074 ? 465  GLU A N   1 
ATOM   3560 C  CA  . GLU A 1 473 ? 6.051   -4.308  56.8    1   29.895 ? 465  GLU A CA  1 
ATOM   3561 C  C   . GLU A 1 473 ? 6.443   -3.114  55.923  1   27.985 ? 465  GLU A C   1 
ATOM   3562 O  O   . GLU A 1 473 ? 6.945   -2.095  56.405  1   26.294 ? 465  GLU A O   1 
ATOM   3563 C  CB  . GLU A 1 473 ? 4.871   -3.85   57.651  1   27.654 ? 465  GLU A CB  1 
ATOM   3564 C  CG  . GLU A 1 473 ? 3.638   -3.5    56.81   1   26.409 ? 465  GLU A CG  1 
ATOM   3565 C  CD  . GLU A 1 473 ? 2.399   -3.123  57.58   1   30.73  ? 465  GLU A CD  1 
ATOM   3566 O  OE1 . GLU A 1 473 ? 2.41    -3.228  58.847  1   27.894 ? 465  GLU A OE1 1 
ATOM   3567 O  OE2 . GLU A 1 473 ? 1.406   -2.733  56.898  1   26.935 ? 465  GLU A OE2 1 
ATOM   3568 N  N   . GLY A 1 474 ? 6.199   -3.221  54.605  1   24.794 ? 466  GLY A N   1 
ATOM   3569 C  CA  . GLY A 1 474 ? 6.412   -2.071  53.737  1   23.362 ? 466  GLY A CA  1 
ATOM   3570 C  C   . GLY A 1 474 ? 7.883   -1.829  53.403  1   25.463 ? 466  GLY A C   1 
ATOM   3571 O  O   . GLY A 1 474 ? 8.197   -0.797  52.835  1   25.178 ? 466  GLY A O   1 
ATOM   3572 N  N   . ASP A 1 475 ? 8.777   -2.75   53.795  1   24.881 ? 467  ASP A N   1 
ATOM   3573 C  CA  . ASP A 1 475 ? 10.194  -2.633  53.473  1   26.717 ? 467  ASP A CA  1 
ATOM   3574 C  C   . ASP A 1 475 ? 10.546  -3.534  52.296  1   25.533 ? 467  ASP A C   1 
ATOM   3575 O  O   . ASP A 1 475 ? 10.473  -4.769  52.384  1   27.366 ? 467  ASP A O   1 
ATOM   3576 C  CB  . ASP A 1 475 ? 11.084  -2.955  54.668  1   25.991 ? 467  ASP A CB  1 
ATOM   3577 C  CG  . ASP A 1 475 ? 12.563  -2.902  54.319  1   28.209 ? 467  ASP A CG  1 
ATOM   3578 O  OD1 . ASP A 1 475 ? 13.041  -1.809  53.951  1   29.944 ? 467  ASP A OD1 1 
ATOM   3579 O  OD2 . ASP A 1 475 ? 13.22   -3.954  54.402  1   35.412 ? 467  ASP A OD2 1 
ATOM   3580 N  N   . GLY A 1 476 ? 10.912  -2.907  51.175  1   27.246 ? 468  GLY A N   1 
ATOM   3581 C  CA  . GLY A 1 476 ? 11.092  -3.686  49.956  1   24.488 ? 468  GLY A CA  1 
ATOM   3582 C  C   . GLY A 1 476 ? 11.011  -2.79   48.727  1   26.112 ? 468  GLY A C   1 
ATOM   3583 O  O   . GLY A 1 476 ? 11.515  -1.664  48.728  1   25.327 ? 468  GLY A O   1 
ATOM   3584 N  N   . PHE A 1 477 ? 10.36   -3.327  47.683  1   23.172 ? 469  PHE A N   1 
ATOM   3585 C  CA  . PHE A 1 477 ? 10.4    -2.687  46.381  1   22.96  ? 469  PHE A CA  1 
ATOM   3586 C  C   . PHE A 1 477 ? 8.968   -2.476  45.914  1   22.642 ? 469  PHE A C   1 
ATOM   3587 O  O   . PHE A 1 477 ? 8.118   -3.351  46.137  1   23.392 ? 469  PHE A O   1 
ATOM   3588 C  CB  . PHE A 1 477 ? 11.21   -3.518  45.371  1   21.565 ? 469  PHE A CB  1 
ATOM   3589 C  CG  . PHE A 1 477 ? 12.657  -3.659  45.859  1   23.204 ? 469  PHE A CG  1 
ATOM   3590 C  CD1 . PHE A 1 477 ? 13.581  -2.626  45.664  1   27.364 ? 469  PHE A CD1 1 
ATOM   3591 C  CD2 . PHE A 1 477 ? 13.055  -4.817  46.546  1   24.991 ? 469  PHE A CD2 1 
ATOM   3592 C  CE1 . PHE A 1 477 ? 14.889  -2.738  46.144  1   27.128 ? 469  PHE A CE1 1 
ATOM   3593 C  CE2 . PHE A 1 477 ? 14.36   -4.938  47.038  1   25.748 ? 469  PHE A CE2 1 
ATOM   3594 C  CZ  . PHE A 1 477 ? 15.258  -3.891  46.833  1   25.708 ? 469  PHE A CZ  1 
ATOM   3595 N  N   . VAL A 1 478 ? 8.748   -1.28   45.345  1   20.99  ? 470  VAL A N   1 
ATOM   3596 C  CA  . VAL A 1 478 ? 7.478   -0.966  44.694  1   22.537 ? 470  VAL A CA  1 
ATOM   3597 C  C   . VAL A 1 478 ? 7.711   -0.928  43.193  1   22.81  ? 470  VAL A C   1 
ATOM   3598 O  O   . VAL A 1 478 ? 8.668   -0.319  42.736  1   23.562 ? 470  VAL A O   1 
ATOM   3599 C  CB  . VAL A 1 478 ? 6.927   0.356   45.262  1   24.989 ? 470  VAL A CB  1 
ATOM   3600 C  CG1 . VAL A 1 478 ? 5.748   0.917   44.457  1   23.051 ? 470  VAL A CG1 1 
ATOM   3601 C  CG2 . VAL A 1 478 ? 6.509   0.123   46.71   1   21.681 ? 470  VAL A CG2 1 
ATOM   3602 N  N   . LEU A 1 479 ? 6.781   -1.554  42.448  1   22.146 ? 471  LEU A N   1 
ATOM   3603 C  CA  . LEU A 1 479 ? 6.861   -1.58   40.997  1   20.961 ? 471  LEU A CA  1 
ATOM   3604 C  C   . LEU A 1 479 ? 5.581   -0.964  40.445  1   21.034 ? 471  LEU A C   1 
ATOM   3605 O  O   . LEU A 1 479 ? 4.521   -1.181  41.014  1   20.949 ? 471  LEU A O   1 
ATOM   3606 C  CB  . LEU A 1 479 ? 7.01    -3.012  40.497  1   21.517 ? 471  LEU A CB  1 
ATOM   3607 C  CG  . LEU A 1 479 ? 8.362   -3.704  40.738  1   25.602 ? 471  LEU A CG  1 
ATOM   3608 C  CD1 . LEU A 1 479 ? 8.515   -4.117  42.21   1   28.787 ? 471  LEU A CD1 1 
ATOM   3609 C  CD2 . LEU A 1 479 ? 8.413   -4.951  39.906  1   27.513 ? 471  LEU A CD2 1 
ATOM   3610 N  N   . ALA A 1 480 ? 5.701   -0.25   39.308  1   19.566 ? 472  ALA A N   1 
ATOM   3611 C  CA  . ALA A 1 480 ? 4.515   0.288   38.653  1   19.385 ? 472  ALA A CA  1 
ATOM   3612 C  C   . ALA A 1 480 ? 4.839   0.536   37.194  1   21.567 ? 472  ALA A C   1 
ATOM   3613 O  O   . ALA A 1 480 ? 5.991   0.82    36.864  1   21.551 ? 472  ALA A O   1 
ATOM   3614 C  CB  . ALA A 1 480 ? 4.041   1.57    39.35   1   20.721 ? 472  ALA A CB  1 
ATOM   3615 N  N   . ILE A 1 481 ? 3.796   0.525   36.359  1   19.39  ? 473  ILE A N   1 
ATOM   3616 C  CA  . ILE A 1 481 ? 3.938   0.864   34.948  1   20.093 ? 473  ILE A CA  1 
ATOM   3617 C  C   . ILE A 1 481 ? 3.859   2.379   34.786  1   20.358 ? 473  ILE A C   1 
ATOM   3618 O  O   . ILE A 1 481 ? 2.897   2.999   35.232  1   20.808 ? 473  ILE A O   1 
ATOM   3619 C  CB  . ILE A 1 481 ? 2.857   0.18    34.083  1   21.394 ? 473  ILE A CB  1 
ATOM   3620 C  CG1 . ILE A 1 481 ? 2.78    -1.344  34.304  1   23.914 ? 473  ILE A CG1 1 
ATOM   3621 C  CG2 . ILE A 1 481 ? 3.028   0.565   32.583  1   20.736 ? 473  ILE A CG2 1 
ATOM   3622 C  CD1 . ILE A 1 481 ? 4.02    -2.16   33.976  1   28.011 ? 473  ILE A CD1 1 
ATOM   3623 N  N   . VAL A 1 482 ? 4.873   2.941   34.102  1   20.174 ? 474  VAL A N   1 
ATOM   3624 C  CA  . VAL A 1 482 ? 4.909   4.343   33.728  1   19.625 ? 474  VAL A CA  1 
ATOM   3625 C  C   . VAL A 1 482 ? 4.622   4.457   32.233  1   22.155 ? 474  VAL A C   1 
ATOM   3626 O  O   . VAL A 1 482 ? 5.258   3.754   31.431  1   23.076 ? 474  VAL A O   1 
ATOM   3627 C  CB  . VAL A 1 482 ? 6.271   4.973   34.075  1   21.915 ? 474  VAL A CB  1 
ATOM   3628 C  CG1 . VAL A 1 482 ? 6.35    6.42    33.582  1   22.035 ? 474  VAL A CG1 1 
ATOM   3629 C  CG2 . VAL A 1 482 ? 6.529   4.871   35.585  1   26.631 ? 474  VAL A CG2 1 
ATOM   3630 N  N   . ASP A 1 483 ? 3.694   5.375   31.89   1   21.163 ? 475  ASP A N   1 
ATOM   3631 C  CA  . ASP A 1 483 ? 3.497   5.775   30.504  1   21.558 ? 475  ASP A CA  1 
ATOM   3632 C  C   . ASP A 1 483 ? 4.377   6.975   30.187  1   25.438 ? 475  ASP A C   1 
ATOM   3633 O  O   . ASP A 1 483 ? 4.203   8.044   30.772  1   26.72  ? 475  ASP A O   1 
ATOM   3634 C  CB  . ASP A 1 483 ? 2.058   6.169   30.214  1   26.412 ? 475  ASP A CB  1 
ATOM   3635 C  CG  . ASP A 1 483 ? 1.05    5.137   30.669  1   31.644 ? 475  ASP A CG  1 
ATOM   3636 O  OD1 . ASP A 1 483 ? 0.741   5.093   31.914  1   31.77  ? 475  ASP A OD1 1 
ATOM   3637 O  OD2 . ASP A 1 483 ? 0.698   4.312   29.82   1   33.337 ? 475  ASP A OD2 1 
ATOM   3638 N  N   . ARG A 1 484 ? 5.331   6.767   29.269  1   23.952 ? 476  ARG A N   1 
ATOM   3639 C  CA  . ARG A 1 484 ? 6.178   7.842   28.759  1   25.663 ? 476  ARG A CA  1 
ATOM   3640 C  C   . ARG A 1 484 ? 5.411   8.422   27.583  1   26.493 ? 476  ARG A C   1 
ATOM   3641 O  O   . ARG A 1 484 ? 5.504   7.928   26.453  1   25.695 ? 476  ARG A O   1 
ATOM   3642 C  CB  . ARG A 1 484 ? 7.573   7.283   28.435  1   22.373 ? 476  ARG A CB  1 
ATOM   3643 C  CG  . ARG A 1 484 ? 8.327   6.62    29.58   1   27.364 ? 476  ARG A CG  1 
ATOM   3644 C  CD  . ARG A 1 484 ? 8.61    7.522   30.747  1   27.87  ? 476  ARG A CD  1 
ATOM   3645 N  NE  . ARG A 1 484 ? 9.45    8.659   30.361  1   28.268 ? 476  ARG A NE  1 
ATOM   3646 C  CZ  . ARG A 1 484 ? 10.779  8.635   30.249  1   31.966 ? 476  ARG A CZ  1 
ATOM   3647 N  NH1 . ARG A 1 484 ? 11.478  7.572   30.624  1   27.7   ? 476  ARG A NH1 1 
ATOM   3648 N  NH2 . ARG A 1 484 ? 11.412  9.69    29.75   1   32.013 ? 476  ARG A NH2 1 
ATOM   3649 N  N   . LEU A 1 485 ? 4.58    9.432   27.893  1   25.689 ? 477  LEU A N   1 
ATOM   3650 C  CA  . LEU A 1 485 ? 3.546   9.878   26.966  1   27.31  ? 477  LEU A CA  1 
ATOM   3651 C  C   . LEU A 1 485 ? 4.123   10.456  25.677  1   30.858 ? 477  LEU A C   1 
ATOM   3652 O  O   . LEU A 1 485 ? 3.481   10.406  24.645  1   35.015 ? 477  LEU A O   1 
ATOM   3653 C  CB  . LEU A 1 485 ? 2.582   10.867  27.595  1   26.864 ? 477  LEU A CB  1 
ATOM   3654 C  CG  . LEU A 1 485 ? 1.74    10.351  28.769  1   32.112 ? 477  LEU A CG  1 
ATOM   3655 C  CD1 . LEU A 1 485 ? 0.986   11.555  29.351  1   32.48  ? 477  LEU A CD1 1 
ATOM   3656 C  CD2 . LEU A 1 485 ? 0.792   9.223   28.341  1   30.135 ? 477  LEU A CD2 1 
ATOM   3657 N  N   . ASP A 1 486 ? 5.294   11.076  25.772  1   31.296 ? 478  ASP A N   1 
ATOM   3658 C  CA  . ASP A 1 486 ? 5.896   11.67   24.591  1   38.546 ? 478  ASP A CA  1 
ATOM   3659 C  C   . ASP A 1 486 ? 6.728   10.643  23.807  1   43.325 ? 478  ASP A C   1 
ATOM   3660 O  O   . ASP A 1 486 ? 7.195   10.964  22.71   1   36.986 ? 478  ASP A O   1 
ATOM   3661 C  CB  . ASP A 1 486 ? 6.706   12.894  24.985  1   38.052 ? 478  ASP A CB  1 
ATOM   3662 C  CG  . ASP A 1 486 ? 7.753   12.67   26.063  1   44.21  ? 478  ASP A CG  1 
ATOM   3663 O  OD1 . ASP A 1 486 ? 7.76    11.59   26.689  1   52.201 ? 478  ASP A OD1 1 
ATOM   3664 O  OD2 . ASP A 1 486 ? 8.56    13.58   26.276  1   57.86  ? 478  ASP A OD2 1 
ATOM   3665 N  N   . LEU A 1 487 ? 6.893   9.414   24.341  1   37.57  ? 479  LEU A N   1 
ATOM   3666 C  CA  . LEU A 1 487 ? 7.844   8.469   23.77   1   34.272 ? 479  LEU A CA  1 
ATOM   3667 C  C   . LEU A 1 487 ? 7.146   7.281   23.122  1   34.887 ? 479  LEU A C   1 
ATOM   3668 O  O   . LEU A 1 487 ? 7.841   6.422   22.562  1   35.139 ? 479  LEU A O   1 
ATOM   3669 C  CB  . LEU A 1 487 ? 8.898   8.028   24.795  1   34.063 ? 479  LEU A CB  1 
ATOM   3670 C  CG  . LEU A 1 487 ? 9.787   9.12    25.398  1   36.065 ? 479  LEU A CG  1 
ATOM   3671 C  CD1 . LEU A 1 487 ? 10.787  8.51    26.372  1   33.629 ? 479  LEU A CD1 1 
ATOM   3672 C  CD2 . LEU A 1 487 ? 10.545  9.939   24.343  1   45.947 ? 479  LEU A CD2 1 
ATOM   3673 N  N   . ASN A 1 488 ? 5.804   7.201   23.22   1   29.243 ? 480  ASN A N   1 
ATOM   3674 C  CA  . ASN A 1 488 ? 5.041   6.026   22.781  1   31.562 ? 480  ASN A CA  1 
ATOM   3675 C  C   . ASN A 1 488 ? 5.678   4.758   23.372  1   29.575 ? 480  ASN A C   1 
ATOM   3676 O  O   . ASN A 1 488 ? 5.848   3.755   22.666  1   30.934 ? 480  ASN A O   1 
ATOM   3677 C  CB  . ASN A 1 488 ? 4.782   5.99    21.26   1   29.548 ? 480  ASN A CB  1 
ATOM   3678 C  CG  . ASN A 1 488 ? 3.829   4.905   20.736  1   35.472 ? 480  ASN A CG  1 
ATOM   3679 O  OD1 . ASN A 1 488 ? 2.787   4.636   21.333  1   33.496 ? 480  ASN A OD1 1 
ATOM   3680 N  ND2 . ASN A 1 488 ? 4.066   4.314   19.566  1   32.171 ? 480  ASN A ND2 1 
ATOM   3681 N  N   . ARG A 1 489 ? 6.007   4.782   24.686  1   24.291 ? 481  ARG A N   1 
ATOM   3682 C  CA  . ARG A 1 489 ? 6.424   3.542   25.305  1   21.352 ? 481  ARG A CA  1 
ATOM   3683 C  C   . ARG A 1 489 ? 5.976   3.488   26.766  1   20.994 ? 481  ARG A C   1 
ATOM   3684 O  O   . ARG A 1 489 ? 5.636   4.516   27.396  1   20.883 ? 481  ARG A O   1 
ATOM   3685 C  CB  . ARG A 1 489 ? 7.945   3.295   25.165  1   25.954 ? 481  ARG A CB  1 
ATOM   3686 C  CG  . ARG A 1 489 ? 8.821   4.148   26.058  1   27.048 ? 481  ARG A CG  1 
ATOM   3687 C  CD  . ARG A 1 489 ? 10.254  3.606   25.918  1   31.369 ? 481  ARG A CD  1 
ATOM   3688 N  NE  . ARG A 1 489 ? 11.044  4.276   26.953  1   35.458 ? 481  ARG A NE  1 
ATOM   3689 C  CZ  . ARG A 1 489 ? 12.034  5.102   26.681  1   32.822 ? 481  ARG A CZ  1 
ATOM   3690 N  NH1 . ARG A 1 489 ? 12.415  5.343   25.437  1   34.49  ? 481  ARG A NH1 1 
ATOM   3691 N  NH2 . ARG A 1 489 ? 12.637  5.703   27.688  1   39.716 ? 481  ARG A NH2 1 
ATOM   3692 N  N   . SER A 1 490 ? 5.99    2.264   27.28   1   20.296 ? 482  SER A N   1 
ATOM   3693 C  CA  . SER A 1 490 ? 5.697   1.981   28.675  1   18.857 ? 482  SER A CA  1 
ATOM   3694 C  C   . SER A 1 490 ? 6.953   1.423   29.33   1   21.555 ? 482  SER A C   1 
ATOM   3695 O  O   . SER A 1 490 ? 7.794   0.818   28.661  1   21.004 ? 482  SER A O   1 
ATOM   3696 C  CB  . SER A 1 490 ? 4.53    1.004   28.768  1   20.42  ? 482  SER A CB  1 
ATOM   3697 O  OG  . SER A 1 490 ? 3.343   1.551   28.162  1   20.348 ? 482  SER A OG  1 
ATOM   3698 N  N   . GLU A 1 491 ? 7.092   1.672   30.642  1   20.998 ? 483  GLU A N   1 
ATOM   3699 C  CA  . GLU A 1 491 ? 8.238   1.218   31.399  1   21.103 ? 483  GLU A CA  1 
ATOM   3700 C  C   . GLU A 1 491 ? 7.756   0.691   32.743  1   21.964 ? 483  GLU A C   1 
ATOM   3701 O  O   . GLU A 1 491 ? 6.699   1.09    33.181  1   23.956 ? 483  GLU A O   1 
ATOM   3702 C  CB  . GLU A 1 491 ? 9.263   2.33    31.711  1   24.281 ? 483  GLU A CB  1 
ATOM   3703 C  CG  . GLU A 1 491 ? 9.745   3.059   30.468  1   33.426 ? 483  GLU A CG  1 
ATOM   3704 C  CD  . GLU A 1 491 ? 10.778  4.134   30.713  1   30.106 ? 483  GLU A CD  1 
ATOM   3705 O  OE1 . GLU A 1 491 ? 10.817  4.852   31.749  1   31.376 ? 483  GLU A OE1 1 
ATOM   3706 O  OE2 . GLU A 1 491 ? 11.486  4.265   29.701  1   37.296 ? 483  GLU A OE2 1 
ATOM   3707 N  N   . VAL A 1 492 ? 8.53    -0.202  33.367  1   20.303 ? 484  VAL A N   1 
ATOM   3708 C  CA  . VAL A 1 492 ? 8.24    -0.598  34.736  1   19.562 ? 484  VAL A CA  1 
ATOM   3709 C  C   . VAL A 1 492 ? 9.278   0.125   35.585  1   22.64  ? 484  VAL A C   1 
ATOM   3710 O  O   . VAL A 1 492 ? 10.457  -0.107  35.402  1   24.71  ? 484  VAL A O   1 
ATOM   3711 C  CB  . VAL A 1 492 ? 8.293   -2.112  35.041  1   21.983 ? 484  VAL A CB  1 
ATOM   3712 C  CG1 . VAL A 1 492 ? 7.748   -2.437  36.447  1   22.433 ? 484  VAL A CG1 1 
ATOM   3713 C  CG2 . VAL A 1 492 ? 7.515   -2.935  34.01   1   20.698 ? 484  VAL A CG2 1 
ATOM   3714 N  N   . VAL A 1 493 ? 8.836   0.943   36.538  1   24.18  ? 485  VAL A N   1 
ATOM   3715 C  CA  . VAL A 1 493 ? 9.786   1.534   37.464  1   24.632 ? 485  VAL A CA  1 
ATOM   3716 C  C   . VAL A 1 493 ? 9.898   0.625   38.686  1   22.148 ? 485  VAL A C   1 
ATOM   3717 O  O   . VAL A 1 493 ? 8.932   -0.014  39.087  1   22.622 ? 485  VAL A O   1 
ATOM   3718 C  CB  . VAL A 1 493 ? 9.326   2.976   37.772  1   29.942 ? 485  VAL A CB  1 
ATOM   3719 C  CG1 . VAL A 1 493 ? 8.082   3.094   38.69   1   23.645 ? 485  VAL A CG1 1 
ATOM   3720 C  CG2 . VAL A 1 493 ? 10.454  3.818   38.309  1   38.479 ? 485  VAL A CG2 1 
ATOM   3721 N  N   . VAL A 1 494 ? 11.101  0.589   39.283  1   21.908 ? 486  VAL A N   1 
ATOM   3722 C  CA  . VAL A 1 494 ? 11.347  -0.127  40.51   1   22.15  ? 486  VAL A CA  1 
ATOM   3723 C  C   . VAL A 1 494 ? 11.877  0.894   41.522  1   24.676 ? 486  VAL A C   1 
ATOM   3724 O  O   . VAL A 1 494 ? 12.851  1.603   41.245  1   24.191 ? 486  VAL A O   1 
ATOM   3725 C  CB  . VAL A 1 494 ? 12.39   -1.259  40.306  1   25.211 ? 486  VAL A CB  1 
ATOM   3726 C  CG1 . VAL A 1 494 ? 12.561  -2.067  41.591  1   23.307 ? 486  VAL A CG1 1 
ATOM   3727 C  CG2 . VAL A 1 494 ? 12.01   -2.199  39.177  1   28.355 ? 486  VAL A CG2 1 
ATOM   3728 N  N   . ILE A 1 495 ? 11.234  0.932   42.697  1   23.518 ? 487  ILE A N   1 
ATOM   3729 C  CA  . ILE A 1 495 ? 11.522  1.927   43.731  1   23.985 ? 487  ILE A CA  1 
ATOM   3730 C  C   . ILE A 1 495 ? 11.861  1.152   44.999  1   25.613 ? 487  ILE A C   1 
ATOM   3731 O  O   . ILE A 1 495 ? 11.128  0.251   45.369  1   24.796 ? 487  ILE A O   1 
ATOM   3732 C  CB  . ILE A 1 495 ? 10.311  2.87    43.955  1   25.068 ? 487  ILE A CB  1 
ATOM   3733 C  CG1 . ILE A 1 495 ? 9.989   3.729   42.718  1   25.819 ? 487  ILE A CG1 1 
ATOM   3734 C  CG2 . ILE A 1 495 ? 10.489  3.756   45.208  1   27.161 ? 487  ILE A CG2 1 
ATOM   3735 C  CD1 . ILE A 1 495 ? 8.522   4.189   42.7    1   25.106 ? 487  ILE A CD1 1 
ATOM   3736 N  N   . ASP A 1 496 ? 12.972  1.508   45.649  1   22.532 ? 488  ASP A N   1 
ATOM   3737 C  CA  . ASP A 1 496 ? 13.275  0.965   46.969  1   25.207 ? 488  ASP A CA  1 
ATOM   3738 C  C   . ASP A 1 496 ? 12.563  1.833   48.014  1   24.619 ? 488  ASP A C   1 
ATOM   3739 O  O   . ASP A 1 496 ? 12.703  3.057   47.979  1   27.034 ? 488  ASP A O   1 
ATOM   3740 C  CB  . ASP A 1 496 ? 14.797  0.87    47.154  1   23.649 ? 488  ASP A CB  1 
ATOM   3741 C  CG  . ASP A 1 496 ? 15.234  0.156   48.43   1   26.234 ? 488  ASP A CG  1 
ATOM   3742 O  OD1 . ASP A 1 496 ? 14.564  0.356   49.464  1   26.478 ? 488  ASP A OD1 1 
ATOM   3743 O  OD2 . ASP A 1 496 ? 16.189  -0.654  48.381  1   30.534 ? 488  ASP A OD2 1 
ATOM   3744 N  N   . THR A 1 497 ? 11.799  1.213   48.944  1   26.132 ? 489  THR A N   1 
ATOM   3745 C  CA  . THR A 1 497 ? 11.042  1.956   49.959  1   30.384 ? 489  THR A CA  1 
ATOM   3746 C  C   . THR A 1 497 ? 11.954  2.726   50.93   1   27.317 ? 489  THR A C   1 
ATOM   3747 O  O   . THR A 1 497 ? 11.485  3.684   51.564  1   26.821 ? 489  THR A O   1 
ATOM   3748 C  CB  . THR A 1 497 ? 10.008  1.105   50.713  1   28.169 ? 489  THR A CB  1 
ATOM   3749 O  OG1 . THR A 1 497 ? 10.77   0.111   51.39   1   30.483 ? 489  THR A OG1 1 
ATOM   3750 C  CG2 . THR A 1 497 ? 8.961   0.509   49.77   1   28.115 ? 489  THR A CG2 1 
ATOM   3751 N  N   . ARG A 1 498 ? 13.247  2.369   50.976  1   29.088 ? 490  ARG A N   1 
ATOM   3752 C  CA  . ARG A 1 498 ? 14.228  3.119   51.749  1   31.325 ? 490  ARG A CA  1 
ATOM   3753 C  C   . ARG A 1 498 ? 14.454  4.517   51.167  1   34.514 ? 490  ARG A C   1 
ATOM   3754 O  O   . ARG A 1 498 ? 14.942  5.385   51.868  1   36.645 ? 490  ARG A O   1 
ATOM   3755 C  CB  . ARG A 1 498 ? 15.565  2.382   51.869  1   33.129 ? 490  ARG A CB  1 
ATOM   3756 C  CG  . ARG A 1 498 ? 15.6    1.137   52.728  1   40.348 ? 490  ARG A CG  1 
ATOM   3757 C  CD  . ARG A 1 498 ? 16.98   0.598   52.386  1   50.626 ? 490  ARG A CD  1 
ATOM   3758 N  NE  . ARG A 1 498 ? 17.184  -0.754  52.918  1   58.024 ? 490  ARG A NE  1 
ATOM   3759 C  CZ  . ARG A 1 498 ? 18.218  -1.573  52.731  1   58.192 ? 490  ARG A CZ  1 
ATOM   3760 N  NH1 . ARG A 1 498 ? 19.242  -1.233  51.974  1   57.961 ? 490  ARG A NH1 1 
ATOM   3761 N  NH2 . ARG A 1 498 ? 18.215  -2.757  53.308  1   58.236 ? 490  ARG A NH2 1 
ATOM   3762 N  N   . ASP A 1 499 ? 14.16   4.732   49.867  1   29.677 ? 491  ASP A N   1 
ATOM   3763 C  CA  . ASP A 1 499 ? 14.099  6.073   49.321  1   28.895 ? 491  ASP A CA  1 
ATOM   3764 C  C   . ASP A 1 499 ? 13.006  6.116   48.263  1   32.315 ? 491  ASP A C   1 
ATOM   3765 O  O   . ASP A 1 499 ? 13.268  5.951   47.066  1   29.693 ? 491  ASP A O   1 
ATOM   3766 C  CB  . ASP A 1 499 ? 15.442  6.596   48.823  1   33.692 ? 491  ASP A CB  1 
ATOM   3767 C  CG  . ASP A 1 499 ? 15.379  8.017   48.279  1   41.077 ? 491  ASP A CG  1 
ATOM   3768 O  OD1 . ASP A 1 499 ? 14.283  8.692   48.382  1   41.275 ? 491  ASP A OD1 1 
ATOM   3769 O  OD2 . ASP A 1 499 ? 16.385  8.434   47.702  1   47.872 ? 491  ASP A OD2 1 
ATOM   3770 N  N   . PHE A 1 500 ? 11.789  6.4     48.734  1   31.396 ? 492  PHE A N   1 
ATOM   3771 C  CA  . PHE A 1 500 ? 10.604  6.285   47.904  1   27.128 ? 492  PHE A CA  1 
ATOM   3772 C  C   . PHE A 1 500 ? 10.579  7.316   46.771  1   31.245 ? 492  PHE A C   1 
ATOM   3773 O  O   . PHE A 1 500 ? 9.829   7.142   45.806  1   26.626 ? 492  PHE A O   1 
ATOM   3774 C  CB  . PHE A 1 500 ? 9.354   6.356   48.783  1   25.414 ? 492  PHE A CB  1 
ATOM   3775 C  CG  . PHE A 1 500 ? 8.117   5.814   48.066  1   26.477 ? 492  PHE A CG  1 
ATOM   3776 C  CD1 . PHE A 1 500 ? 7.965   4.441   47.827  1   26.957 ? 492  PHE A CD1 1 
ATOM   3777 C  CD2 . PHE A 1 500 ? 7.119   6.692   47.623  1   24.215 ? 492  PHE A CD2 1 
ATOM   3778 C  CE1 . PHE A 1 500 ? 6.828   3.954   47.171  1   24.967 ? 492  PHE A CE1 1 
ATOM   3779 C  CE2 . PHE A 1 500 ? 5.987   6.204   46.964  1   27.371 ? 492  PHE A CE2 1 
ATOM   3780 C  CZ  . PHE A 1 500 ? 5.835   4.846   46.753  1   23.901 ? 492  PHE A CZ  1 
ATOM   3781 N  N   . THR A 1 501 ? 11.402  8.387   46.86   1   28.299 ? 493  THR A N   1 
ATOM   3782 C  CA  . THR A 1 501 ? 11.309  9.474   45.891  1   29.123 ? 493  THR A CA  1 
ATOM   3783 C  C   . THR A 1 501 ? 12.07   9.133   44.601  1   28.3   ? 493  THR A C   1 
ATOM   3784 O  O   . THR A 1 501 ? 11.909  9.845   43.622  1   29.413 ? 493  THR A O   1 
ATOM   3785 C  CB  . THR A 1 501 ? 11.732  10.817  46.503  1   32.848 ? 493  THR A CB  1 
ATOM   3786 O  OG1 . THR A 1 501 ? 13.158  10.718  46.518  1   31.411 ? 493  THR A OG1 1 
ATOM   3787 C  CG2 . THR A 1 501 ? 11.156  11.062  47.892  1   27.41  ? 493  THR A CG2 1 
ATOM   3788 N  N   . LYS A 1 502 ? 12.859  8.049   44.6    1   29.049 ? 494  LYS A N   1 
ATOM   3789 C  CA  . LYS A 1 502 ? 13.778  7.717   43.507  1   33.92  ? 494  LYS A CA  1 
ATOM   3790 C  C   . LYS A 1 502 ? 13.572  6.287   42.988  1   29.521 ? 494  LYS A C   1 
ATOM   3791 O  O   . LYS A 1 502 ? 13.498  5.327   43.753  1   31.604 ? 494  LYS A O   1 
ATOM   3792 C  CB  . LYS A 1 502 ? 15.224  7.886   44.002  1   40.032 ? 494  LYS A CB  1 
ATOM   3793 C  CG  . LYS A 1 502 ? 16.344  7.726   42.964  1   50.837 ? 494  LYS A CG  1 
ATOM   3794 C  CD  . LYS A 1 502 ? 17.578  8.522   43.382  1   60.559 ? 494  LYS A CD  1 
ATOM   3795 C  CE  . LYS A 1 502 ? 18.716  8.617   42.404  1   62.909 ? 494  LYS A CE  1 
ATOM   3796 N  NZ  . LYS A 1 502 ? 19.696  7.558   42.64   1   68.623 ? 494  LYS A NZ  1 
ATOM   3797 N  N   . ALA A 1 503 ? 13.549  6.137   41.657  1   30.139 ? 495  ALA A N   1 
ATOM   3798 C  CA  . ALA A 1 503 ? 13.616  4.83    41.021  1   26.464 ? 495  ALA A CA  1 
ATOM   3799 C  C   . ALA A 1 503 ? 15.044  4.291   41.068  1   28.013 ? 495  ALA A C   1 
ATOM   3800 O  O   . ALA A 1 503 ? 15.999  5.04    40.8    1   31.562 ? 495  ALA A O   1 
ATOM   3801 C  CB  . ALA A 1 503 ? 13.199  4.972   39.579  1   27.913 ? 495  ALA A CB  1 
ATOM   3802 N  N   . VAL A 1 504 ? 15.182  3.003   41.398  1   24.391 ? 496  VAL A N   1 
ATOM   3803 C  CA  . VAL A 1 504 ? 16.478  2.328   41.317  1   28.019 ? 496  VAL A CA  1 
ATOM   3804 C  C   . VAL A 1 504 ? 16.692  1.773   39.908  1   33.162 ? 496  VAL A C   1 
ATOM   3805 O  O   . VAL A 1 504 ? 17.837  1.564   39.486  1   29.646 ? 496  VAL A O   1 
ATOM   3806 C  CB  . VAL A 1 504 ? 16.767  1.237   42.372  1   27.77  ? 496  VAL A CB  1 
ATOM   3807 C  CG1 . VAL A 1 504 ? 16.922  1.831   43.771  1   27.872 ? 496  VAL A CG1 1 
ATOM   3808 C  CG2 . VAL A 1 504 ? 15.736  0.101   42.361  1   30.224 ? 496  VAL A CG2 1 
ATOM   3809 N  N   . ALA A 1 505 ? 15.586  1.442   39.217  1   24.755 ? 497  ALA A N   1 
ATOM   3810 C  CA  . ALA A 1 505 ? 15.748  0.824   37.904  1   25.89  ? 497  ALA A CA  1 
ATOM   3811 C  C   . ALA A 1 505 ? 14.494  1.125   37.091  1   22.834 ? 497  ALA A C   1 
ATOM   3812 O  O   . ALA A 1 505 ? 13.448  1.423   37.666  1   23.262 ? 497  ALA A O   1 
ATOM   3813 C  CB  . ALA A 1 505 ? 15.943  -0.677  38.038  1   27.076 ? 497  ALA A CB  1 
ATOM   3814 N  N   . ALA A 1 506 ? 14.629  1.019   35.776  1   23.358 ? 498  ALA A N   1 
ATOM   3815 C  CA  . ALA A 1 506 ? 13.446  1.042   34.915  1   22.638 ? 498  ALA A CA  1 
ATOM   3816 C  C   . ALA A 1 506 ? 13.557  -0.105  33.919  1   26.652 ? 498  ALA A C   1 
ATOM   3817 O  O   . ALA A 1 506 ? 14.647  -0.341  33.397  1   27.697 ? 498  ALA A O   1 
ATOM   3818 C  CB  . ALA A 1 506 ? 13.329  2.39    34.234  1   23.15  ? 498  ALA A CB  1 
ATOM   3819 N  N   . VAL A 1 507 ? 12.456  -0.841  33.708  1   21.597 ? 499  VAL A N   1 
ATOM   3820 C  CA  . VAL A 1 507 ? 12.413  -1.886  32.71   1   21.42  ? 499  VAL A CA  1 
ATOM   3821 C  C   . VAL A 1 507 ? 11.802  -1.202  31.492  1   23.725 ? 499  VAL A C   1 
ATOM   3822 O  O   . VAL A 1 507 ? 10.699  -0.658  31.6    1   25.773 ? 499  VAL A O   1 
ATOM   3823 C  CB  . VAL A 1 507 ? 11.515  -3.04   33.202  1   24.385 ? 499  VAL A CB  1 
ATOM   3824 C  CG1 . VAL A 1 507 ? 11.423  -4.123  32.126  1   21.192 ? 499  VAL A CG1 1 
ATOM   3825 C  CG2 . VAL A 1 507 ? 12.036  -3.653  34.509  1   21.582 ? 499  VAL A CG2 1 
ATOM   3826 N  N   . GLN A 1 508 ? 12.533  -1.196  30.377  1   19.147 ? 500  GLN A N   1 
ATOM   3827 C  CA  . GLN A 1 508 ? 12.143  -0.352  29.268  1   20.447 ? 500  GLN A CA  1 
ATOM   3828 C  C   . GLN A 1 508 ? 11.608  -1.235  28.147  1   23.572 ? 500  GLN A C   1 
ATOM   3829 O  O   . GLN A 1 508 ? 12.404  -1.867  27.453  1   21.27  ? 500  GLN A O   1 
ATOM   3830 C  CB  . GLN A 1 508 ? 13.376  0.464   28.844  1   26.754 ? 500  GLN A CB  1 
ATOM   3831 C  CG  . GLN A 1 508 ? 13.154  1.428   27.678  1   26.977 ? 500  GLN A CG  1 
ATOM   3832 C  CD  . GLN A 1 508 ? 14.435  2.118   27.237  1   32.169 ? 500  GLN A CD  1 
ATOM   3833 O  OE1 . GLN A 1 508 ? 15.327  2.378   28.067  1   30.043 ? 500  GLN A OE1 1 
ATOM   3834 N  NE2 . GLN A 1 508 ? 14.554  2.353   25.932  1   33.561 ? 500  GLN A NE2 1 
ATOM   3835 N  N   . LEU A 1 509 ? 10.274  -1.225  27.937  1   19.584 ? 501  LEU A N   1 
ATOM   3836 C  CA  . LEU A 1 509 ? 9.725   -1.866  26.764  1   18.657 ? 501  LEU A CA  1 
ATOM   3837 C  C   . LEU A 1 509 ? 10.071  -1.078  25.506  1   19.571 ? 501  LEU A C   1 
ATOM   3838 O  O   . LEU A 1 509 ? 10.27   0.144   25.559  1   21.149 ? 501  LEU A O   1 
ATOM   3839 C  CB  . LEU A 1 509 ? 8.204   -2.054  26.876  1   18.395 ? 501  LEU A CB  1 
ATOM   3840 C  CG  . LEU A 1 509 ? 7.74    -3.012  27.97   1   22.168 ? 501  LEU A CG  1 
ATOM   3841 C  CD1 . LEU A 1 509 ? 6.224   -2.873  28.093  1   21.861 ? 501  LEU A CD1 1 
ATOM   3842 C  CD2 . LEU A 1 509 ? 8.036   -4.478  27.568  1   20.256 ? 501  LEU A CD2 1 
ATOM   3843 N  N   . PRO A 1 510 ? 10.127  -1.75   24.322  1   19.478 ? 502  PRO A N   1 
ATOM   3844 C  CA  . PRO A 1 510 ? 10.304  -1.067  23.052  1   20.714 ? 502  PRO A CA  1 
ATOM   3845 C  C   . PRO A 1 510 ? 9.008   -0.503  22.464  1   24.82  ? 502  PRO A C   1 
ATOM   3846 O  O   . PRO A 1 510 ? 8.974   -0.091  21.292  1   28.019 ? 502  PRO A O   1 
ATOM   3847 C  CB  . PRO A 1 510 ? 10.813  -2.171  22.115  1   19.892 ? 502  PRO A CB  1 
ATOM   3848 C  CG  . PRO A 1 510 ? 10.151  -3.412  22.646  1   20.638 ? 502  PRO A CG  1 
ATOM   3849 C  CD  . PRO A 1 510 ? 10.054  -3.21   24.175  1   20.486 ? 502  PRO A CD  1 
ATOM   3850 N  N   . PHE A 1 511 ? 7.957   -0.495  23.277  1   24.24  ? 503  PHE A N   1 
ATOM   3851 C  CA  . PHE A 1 511 ? 6.632   -0.05   22.846  1   21.836 ? 503  PHE A CA  1 
ATOM   3852 C  C   . PHE A 1 511 ? 5.782   0.311   24.072  1   23.929 ? 503  PHE A C   1 
ATOM   3853 O  O   . PHE A 1 511 ? 6.232   0.137   25.224  1   22.308 ? 503  PHE A O   1 
ATOM   3854 C  CB  . PHE A 1 511 ? 5.975   -1.117  21.959  1   23.092 ? 503  PHE A CB  1 
ATOM   3855 C  CG  . PHE A 1 511 ? 5.963   -2.536  22.503  1   23.224 ? 503  PHE A CG  1 
ATOM   3856 C  CD1 . PHE A 1 511 ? 5.518   -2.839  23.808  1   26.555 ? 503  PHE A CD1 1 
ATOM   3857 C  CD2 . PHE A 1 511 ? 6.359   -3.588  21.691  1   23.036 ? 503  PHE A CD2 1 
ATOM   3858 C  CE1 . PHE A 1 511 ? 5.509   -4.135  24.306  1   25.764 ? 503  PHE A CE1 1 
ATOM   3859 C  CE2 . PHE A 1 511 ? 6.355   -4.895  22.191  1   25.188 ? 503  PHE A CE2 1 
ATOM   3860 C  CZ  . PHE A 1 511 ? 5.923   -5.174  23.484  1   25.029 ? 503  PHE A CZ  1 
ATOM   3861 N  N   . ALA A 1 512 ? 4.578   0.844   23.789  1   21.316 ? 504  ALA A N   1 
ATOM   3862 C  CA  . ALA A 1 512 ? 3.601   1.134   24.831  1   20.61  ? 504  ALA A CA  1 
ATOM   3863 C  C   . ALA A 1 512 ? 2.586   0.006   24.933  1   22.557 ? 504  ALA A C   1 
ATOM   3864 O  O   . ALA A 1 512 ? 2.254   -0.629  23.931  1   20.622 ? 504  ALA A O   1 
ATOM   3865 C  CB  . ALA A 1 512 ? 2.901   2.457   24.582  1   23.039 ? 504  ALA A CB  1 
ATOM   3866 N  N   . ILE A 1 513 ? 2.122   -0.25   26.164  1   20.077 ? 505  ILE A N   1 
ATOM   3867 C  CA  . ILE A 1 513 ? 1.011   -1.162  26.383  1   22.29  ? 505  ILE A CA  1 
ATOM   3868 C  C   . ILE A 1 513 ? -0.178  -0.321  26.858  1   19.207 ? 505  ILE A C   1 
ATOM   3869 O  O   . ILE A 1 513 ? -0.017  0.85    27.202  1   19.24  ? 505  ILE A O   1 
ATOM   3870 C  CB  . ILE A 1 513 ? 1.389   -2.347  27.3    1   24.386 ? 505  ILE A CB  1 
ATOM   3871 C  CG1 . ILE A 1 513 ? 1.81    -1.875  28.714  1   23.448 ? 505  ILE A CG1 1 
ATOM   3872 C  CG2 . ILE A 1 513 ? 2.473   -3.223  26.644  1   24.462 ? 505  ILE A CG2 1 
ATOM   3873 C  CD1 . ILE A 1 513 ? 2.022   -3.004  29.738  1   21.713 ? 505  ILE A CD1 1 
ATOM   3874 N  N   . ARG A 1 514 ? -1.388  -0.9    26.838  1   19.582 ? 506  ARG A N   1 
ATOM   3875 C  CA  . ARG A 1 514 ? -2.561  -0.203  27.348  1   19.402 ? 506  ARG A CA  1 
ATOM   3876 C  C   . ARG A 1 514 ? -2.312  0.252   28.776  1   20.022 ? 506  ARG A C   1 
ATOM   3877 O  O   . ARG A 1 514 ? -1.588  -0.427  29.529  1   18.732 ? 506  ARG A O   1 
ATOM   3878 C  CB  . ARG A 1 514 ? -3.778  -1.143  27.387  1   20.053 ? 506  ARG A CB  1 
ATOM   3879 C  CG  . ARG A 1 514 ? -4.383  -1.229  25.993  1   18.768 ? 506  ARG A CG  1 
ATOM   3880 C  CD  . ARG A 1 514 ? -5.34   -0.061  25.811  1   22.077 ? 506  ARG A CD  1 
ATOM   3881 N  NE  . ARG A 1 514 ? -6.186  -0.203  24.622  1   21.125 ? 506  ARG A NE  1 
ATOM   3882 C  CZ  . ARG A 1 514 ? -7.06   0.717   24.207  1   22.774 ? 506  ARG A CZ  1 
ATOM   3883 N  NH1 . ARG A 1 514 ? -7.197  1.891   24.813  1   23.062 ? 506  ARG A NH1 1 
ATOM   3884 N  NH2 . ARG A 1 514 ? -7.785  0.478   23.125  1   21.498 ? 506  ARG A NH2 1 
ATOM   3885 N  N   . SER A 1 515 ? -2.935  1.378   29.138  1   18.929 ? 507  SER A N   1 
ATOM   3886 C  CA  . SER A 1 515 ? -2.983  1.682   30.569  1   18.646 ? 507  SER A CA  1 
ATOM   3887 C  C   . SER A 1 515 ? -3.963  0.68    31.174  1   21.833 ? 507  SER A C   1 
ATOM   3888 O  O   . SER A 1 515 ? -5.042  0.476   30.618  1   23.793 ? 507  SER A O   1 
ATOM   3889 C  CB  . SER A 1 515 ? -3.392  3.13    30.82   1   19.639 ? 507  SER A CB  1 
ATOM   3890 O  OG  . SER A 1 515 ? -3.385  3.414   32.22   1   21.57  ? 507  SER A OG  1 
ATOM   3891 N  N   . GLY A 1 516 ? -3.589  0.061   32.294  1   19.938 ? 508  GLY A N   1 
ATOM   3892 C  CA  . GLY A 1 516 ? -4.341  -1.098  32.768  1   19.756 ? 508  GLY A CA  1 
ATOM   3893 C  C   . GLY A 1 516 ? -5.17   -0.782  34.019  1   21.116 ? 508  GLY A C   1 
ATOM   3894 O  O   . GLY A 1 516 ? -5.43   0.373   34.354  1   21.989 ? 508  GLY A O   1 
ATOM   3895 N  N   . ILE A 1 517 ? -5.696  -1.847  34.619  1   18.025 ? 509  ILE A N   1 
ATOM   3896 C  CA  . ILE A 1 517 ? -6.566  -1.725  35.768  1   19.452 ? 509  ILE A CA  1 
ATOM   3897 C  C   . ILE A 1 517 ? -5.73   -2.164  36.969  1   18.557 ? 509  ILE A C   1 
ATOM   3898 O  O   . ILE A 1 517 ? -4.976  -1.336  37.487  1   21.169 ? 509  ILE A O   1 
ATOM   3899 C  CB  . ILE A 1 517 ? -7.88   -2.51   35.557  1   19.93  ? 509  ILE A CB  1 
ATOM   3900 C  CG1 . ILE A 1 517 ? -8.463  -2.321  34.147  1   23.902 ? 509  ILE A CG1 1 
ATOM   3901 C  CG2 . ILE A 1 517 ? -8.886  -2.214  36.674  1   19.9   ? 509  ILE A CG2 1 
ATOM   3902 C  CD1 . ILE A 1 517 ? -9.022  -0.966  33.806  1   29.054 ? 509  ILE A CD1 1 
ATOM   3903 N  N   . HIS A 1 518 ? -5.805  -3.446  37.379  1   17.428 ? 510  HIS A N   1 
ATOM   3904 C  CA  . HIS A 1 518 ? -4.943  -3.902  38.459  1   19.039 ? 510  HIS A CA  1 
ATOM   3905 C  C   . HIS A 1 518 ? -3.778  -4.744  37.955  1   21.924 ? 510  HIS A C   1 
ATOM   3906 O  O   . HIS A 1 518 ? -3.737  -5.228  36.809  1   23.434 ? 510  HIS A O   1 
ATOM   3907 C  CB  . HIS A 1 518 ? -5.79   -4.693  39.469  1   18.894 ? 510  HIS A CB  1 
ATOM   3908 C  CG  . HIS A 1 518 ? -6.895  -3.852  40.032  1   19.725 ? 510  HIS A CG  1 
ATOM   3909 N  ND1 . HIS A 1 518 ? -6.642  -2.911  41.008  1   18.509 ? 510  HIS A ND1 1 
ATOM   3910 C  CD2 . HIS A 1 518 ? -8.235  -3.776  39.757  1   19.047 ? 510  HIS A CD2 1 
ATOM   3911 C  CE1 . HIS A 1 518 ? -7.785  -2.286  41.33   1   19.368 ? 510  HIS A CE1 1 
ATOM   3912 N  NE2 . HIS A 1 518 ? -8.749  -2.782  40.572  1   19.293 ? 510  HIS A NE2 1 
ATOM   3913 N  N   . GLY A 1 519 ? -2.82   -4.916  38.859  1   19.35  ? 511  GLY A N   1 
ATOM   3914 C  CA  . GLY A 1 519 ? -1.78   -5.919  38.693  1   18.196 ? 511  GLY A CA  1 
ATOM   3915 C  C   . GLY A 1 519 ? -1.39   -6.439  40.06   1   19.636 ? 511  GLY A C   1 
ATOM   3916 O  O   . GLY A 1 519 ? -1.905  -5.93   41.059  1   19.064 ? 511  GLY A O   1 
ATOM   3917 N  N   . GLN A 1 520 ? -0.524  -7.47   40.088  1   18.666 ? 512  GLN A N   1 
ATOM   3918 C  CA  . GLN A 1 520 ? -0.23   -8.061  41.382  1   18.485 ? 512  GLN A CA  1 
ATOM   3919 C  C   . GLN A 1 520 ? 1.226   -8.482  41.331  1   19.226 ? 512  GLN A C   1 
ATOM   3920 O  O   . GLN A 1 520 ? 1.714   -8.886  40.275  1   19.84  ? 512  GLN A O   1 
ATOM   3921 C  CB  . GLN A 1 520 ? -1.047  -9.313  41.71   1   21.666 ? 512  GLN A CB  1 
ATOM   3922 C  CG  . GLN A 1 520 ? -2.566  -9.111  41.778  1   20.453 ? 512  GLN A CG  1 
ATOM   3923 C  CD  . GLN A 1 520 ? -3.038  -8.206  42.902  1   23.922 ? 512  GLN A CD  1 
ATOM   3924 O  OE1 . GLN A 1 520 ? -2.348  -8.023  43.916  1   24.578 ? 512  GLN A OE1 1 
ATOM   3925 N  NE2 . GLN A 1 520 ? -4.143  -7.512  42.706  1   19.327 ? 512  GLN A NE2 1 
ATOM   3926 N  N   . TRP A 1 521 ? 1.918   -8.277  42.457  1   18.852 ? 513  TRP A N   1 
ATOM   3927 C  CA  . TRP A 1 521 ? 3.184   -8.959  42.652  1   20.527 ? 513  TRP A CA  1 
ATOM   3928 C  C   . TRP A 1 521 ? 2.907   -10.384 43.13   1   21.008 ? 513  TRP A C   1 
ATOM   3929 O  O   . TRP A 1 521 ? 2.39    -10.605 44.231  1   22.361 ? 513  TRP A O   1 
ATOM   3930 C  CB  . TRP A 1 521 ? 4.094   -8.218  43.639  1   20.584 ? 513  TRP A CB  1 
ATOM   3931 C  CG  . TRP A 1 521 ? 5.383   -8.983  43.802  1   21.37  ? 513  TRP A CG  1 
ATOM   3932 C  CD1 . TRP A 1 521 ? 5.77    -9.756  44.86   1   22.867 ? 513  TRP A CD1 1 
ATOM   3933 C  CD2 . TRP A 1 521 ? 6.427   -9.076  42.815  1   23.086 ? 513  TRP A CD2 1 
ATOM   3934 N  NE1 . TRP A 1 521 ? 6.996   -10.339 44.601  1   21.995 ? 513  TRP A NE1 1 
ATOM   3935 C  CE2 . TRP A 1 521 ? 7.431   -9.925  43.358  1   22.398 ? 513  TRP A CE2 1 
ATOM   3936 C  CE3 . TRP A 1 521 ? 6.616   -8.517  41.541  1   21.645 ? 513  TRP A CE3 1 
ATOM   3937 C  CZ2 . TRP A 1 521 ? 8.603   -10.219 42.646  1   21.355 ? 513  TRP A CZ2 1 
ATOM   3938 C  CZ3 . TRP A 1 521 ? 7.765   -8.813  40.839  1   21.518 ? 513  TRP A CZ3 1 
ATOM   3939 C  CH2 . TRP A 1 521 ? 8.742   -9.68   41.378  1   22.063 ? 513  TRP A CH2 1 
ATOM   3940 N  N   . ILE A 1 522 ? 3.336   -11.352 42.326  1   20.36  ? 514  ILE A N   1 
ATOM   3941 C  CA  . ILE A 1 522 ? 3.112   -12.754 42.642  1   20.295 ? 514  ILE A CA  1 
ATOM   3942 C  C   . ILE A 1 522 ? 4.492   -13.375 42.885  1   21.642 ? 514  ILE A C   1 
ATOM   3943 O  O   . ILE A 1 522 ? 5.281   -13.539 41.948  1   23.435 ? 514  ILE A O   1 
ATOM   3944 C  CB  . ILE A 1 522 ? 2.383   -13.498 41.512  1   21.068 ? 514  ILE A CB  1 
ATOM   3945 C  CG1 . ILE A 1 522 ? 1.036   -12.81  41.122  1   24.188 ? 514  ILE A CG1 1 
ATOM   3946 C  CG2 . ILE A 1 522 ? 2.206   -15.001 41.828  1   20.413 ? 514  ILE A CG2 1 
ATOM   3947 C  CD1 . ILE A 1 522 ? -0.006  -12.728 42.217  1   32.336 ? 514  ILE A CD1 1 
ATOM   3948 N  N   . PRO A 1 523 ? 4.788   -13.739 44.144  1   22.528 ? 515  PRO A N   1 
ATOM   3949 C  CA  . PRO A 1 523 ? 6.095   -14.304 44.48   1   24.767 ? 515  PRO A CA  1 
ATOM   3950 C  C   . PRO A 1 523 ? 6.356   -15.604 43.739  1   23.681 ? 515  PRO A C   1 
ATOM   3951 O  O   . PRO A 1 523 ? 5.44    -16.373 43.458  1   22.839 ? 515  PRO A O   1 
ATOM   3952 C  CB  . PRO A 1 523 ? 6.022   -14.514 46.018  1   22.387 ? 515  PRO A CB  1 
ATOM   3953 C  CG  . PRO A 1 523 ? 4.895   -13.591 46.449  1   24.153 ? 515  PRO A CG  1 
ATOM   3954 C  CD  . PRO A 1 523 ? 3.892   -13.645 45.319  1   23.313 ? 515  PRO A CD  1 
ATOM   3955 N  N   . GLY A 1 524 ? 7.634   -15.818 43.379  1   23.622 ? 516  GLY A N   1 
ATOM   3956 C  CA  . GLY A 1 524 ? 8.079   -17.048 42.742  1   25.373 ? 516  GLY A CA  1 
ATOM   3957 C  C   . GLY A 1 524 ? 7.697   -18.291 43.544  1   25.001 ? 516  GLY A C   1 
ATOM   3958 O  O   . GLY A 1 524 ? 7.285   -19.311 42.975  1   26.794 ? 516  GLY A O   1 
ATOM   3959 N  N   . GLU A 1 525 ? 7.762   -18.153 44.887  1   25.346 ? 517  GLU A N   1 
ATOM   3960 C  CA  . GLU A 1 525 ? 7.525   -19.241 45.832  1   26.988 ? 517  GLU A CA  1 
ATOM   3961 C  C   . GLU A 1 525 ? 6.092   -19.781 45.735  1   29.11  ? 517  GLU A C   1 
ATOM   3962 O  O   . GLU A 1 525 ? 5.864   -20.936 46.074  1   30.045 ? 517  GLU A O   1 
ATOM   3963 C  CB  . GLU A 1 525 ? 7.777   -18.602 47.201  1   33.564 ? 517  GLU A CB  1 
ATOM   3964 C  CG  . GLU A 1 525 ? 7.924   -19.574 48.36   1   55.311 ? 517  GLU A CG  1 
ATOM   3965 C  CD  . GLU A 1 525 ? 7.939   -18.861 49.711  1   69.713 ? 517  GLU A CD  1 
ATOM   3966 O  OE1 . GLU A 1 525 ? 7.882   -17.603 49.803  1   65.824 ? 517  GLU A OE1 1 
ATOM   3967 O  OE2 . GLU A 1 525 ? 8.004   -19.608 50.713  1   73.066 ? 517  GLU A OE2 1 
ATOM   3968 N  N   . VAL A 1 526 ? 5.121   -18.966 45.27   1   26.512 ? 518  VAL A N   1 
ATOM   3969 C  CA  . VAL A 1 526 ? 3.732   -19.425 45.171  1   24.06  ? 518  VAL A CA  1 
ATOM   3970 C  C   . VAL A 1 526 ? 3.342   -19.744 43.725  1   24.868 ? 518  VAL A C   1 
ATOM   3971 O  O   . VAL A 1 526 ? 2.177   -20.083 43.466  1   23.291 ? 518  VAL A O   1 
ATOM   3972 C  CB  . VAL A 1 526 ? 2.734   -18.45  45.835  1   27.408 ? 518  VAL A CB  1 
ATOM   3973 C  CG1 . VAL A 1 526 ? 3.049   -18.176 47.315  1   25.635 ? 518  VAL A CG1 1 
ATOM   3974 C  CG2 . VAL A 1 526 ? 2.566   -17.135 45.048  1   26.446 ? 518  VAL A CG2 1 
ATOM   3975 N  N   . THR A 1 527 ? 4.31    -19.671 42.808  1   23.58  ? 519  THR A N   1 
ATOM   3976 C  CA  . THR A 1 527 ? 4.04    -19.917 41.393  1   21.932 ? 519  THR A CA  1 
ATOM   3977 C  C   . THR A 1 527 ? 4.521   -21.334 41.085  1   24.479 ? 519  THR A C   1 
ATOM   3978 O  O   . THR A 1 527 ? 5.722   -21.581 41.238  1   24.062 ? 519  THR A O   1 
ATOM   3979 C  CB  . THR A 1 527 ? 4.782   -18.904 40.511  1   25.137 ? 519  THR A CB  1 
ATOM   3980 O  OG1 . THR A 1 527 ? 4.406   -17.62  41.004  1   25.976 ? 519  THR A OG1 1 
ATOM   3981 C  CG2 . THR A 1 527 ? 4.436   -19.072 39.037  1   21.334 ? 519  THR A CG2 1 
ATOM   3982 N  N   . PRO A 1 528 ? 3.643   -22.263 40.649  1   24.915 ? 520  PRO A N   1 
ATOM   3983 C  CA  . PRO A 1 528 ? 4.085   -23.603 40.249  1   28.407 ? 520  PRO A CA  1 
ATOM   3984 C  C   . PRO A 1 528 ? 5.202   -23.559 39.22   1   27.226 ? 520  PRO A C   1 
ATOM   3985 O  O   . PRO A 1 528 ? 5.123   -22.776 38.264  1   24.408 ? 520  PRO A O   1 
ATOM   3986 C  CB  . PRO A 1 528 ? 2.828   -24.275 39.66   1   25.867 ? 520  PRO A CB  1 
ATOM   3987 C  CG  . PRO A 1 528 ? 1.723   -23.524 40.367  1   27.285 ? 520  PRO A CG  1 
ATOM   3988 C  CD  . PRO A 1 528 ? 2.187   -22.093 40.49   1   24.284 ? 520  PRO A CD  1 
ATOM   3989 N  N   . ASP A 1 529 ? 6.278   -24.325 39.493  1   26.798 ? 521  ASP A N   1 
ATOM   3990 C  CA  . ASP A 1 529 ? 7.412   -24.517 38.581  1   27.596 ? 521  ASP A CA  1 
ATOM   3991 C  C   . ASP A 1 529 ? 8.153   -23.224 38.248  1   26.015 ? 521  ASP A C   1 
ATOM   3992 O  O   . ASP A 1 529 ? 8.777   -23.157 37.174  1   27.066 ? 521  ASP A O   1 
ATOM   3993 C  CB  . ASP A 1 529 ? 6.961   -25.173 37.276  1   30.098 ? 521  ASP A CB  1 
ATOM   3994 C  CG  . ASP A 1 529 ? 6.158   -26.444 37.524  1   33.435 ? 521  ASP A CG  1 
ATOM   3995 O  OD1 . ASP A 1 529 ? 6.75    -27.331 38.122  1   30.596 ? 521  ASP A OD1 1 
ATOM   3996 O  OD2 . ASP A 1 529 ? 4.947   -26.496 37.22   1   36.452 ? 521  ASP A OD2 1 
ATOM   3997 N  N   . PHE A 1 530 ? 8.086   -22.213 39.141  1   23.748 ? 522  PHE A N   1 
ATOM   3998 C  CA  . PHE A 1 530 ? 8.814   -20.969 38.945  1   24.654 ? 522  PHE A CA  1 
ATOM   3999 C  C   . PHE A 1 530 ? 10.312  -21.27  38.759  1   27.252 ? 522  PHE A C   1 
ATOM   4000 O  O   . PHE A 1 530 ? 10.985  -20.583 37.991  1   24.441 ? 522  PHE A O   1 
ATOM   4001 C  CB  . PHE A 1 530 ? 8.609   -19.985 40.1    1   25.042 ? 522  PHE A CB  1 
ATOM   4002 C  CG  . PHE A 1 530 ? 9.197   -18.593 39.875  1   25.287 ? 522  PHE A CG  1 
ATOM   4003 C  CD1 . PHE A 1 530 ? 8.473   -17.597 39.199  1   21.643 ? 522  PHE A CD1 1 
ATOM   4004 C  CD2 . PHE A 1 530 ? 10.481  -18.271 40.346  1   25.323 ? 522  PHE A CD2 1 
ATOM   4005 C  CE1 . PHE A 1 530 ? 9.016   -16.324 39.015  1   22.741 ? 522  PHE A CE1 1 
ATOM   4006 C  CE2 . PHE A 1 530 ? 11.03   -17.01  40.147  1   23.712 ? 522  PHE A CE2 1 
ATOM   4007 C  CZ  . PHE A 1 530 ? 10.319  -16.043 39.453  1   26.292 ? 522  PHE A CZ  1 
ATOM   4008 N  N   . GLU A 1 531 ? 10.826  -22.301 39.461  1   28.087 ? 523  GLU A N   1 
ATOM   4009 C  CA  . GLU A 1 531 ? 12.256  -22.606 39.434  1   31.526 ? 523  GLU A CA  1 
ATOM   4010 C  C   . GLU A 1 531 ? 12.705  -23.222 38.108  1   30.88  ? 523  GLU A C   1 
ATOM   4011 O  O   . GLU A 1 531 ? 13.894  -23.2   37.823  1   36.77  ? 523  GLU A O   1 
ATOM   4012 C  CB  . GLU A 1 531 ? 12.754  -23.406 40.649  1   29.011 ? 523  GLU A CB  1 
ATOM   4013 C  CG  . GLU A 1 531 ? 12.541  -22.675 41.977  1   27.904 ? 523  GLU A CG  1 
ATOM   4014 C  CD  . GLU A 1 531 ? 13.165  -21.288 42.088  1   36.178 ? 523  GLU A CD  1 
ATOM   4015 O  OE1 . GLU A 1 531 ? 14.298  -21.092 41.604  1   43.032 ? 523  GLU A OE1 1 
ATOM   4016 O  OE2 . GLU A 1 531 ? 12.536  -20.389 42.677  1   37.401 ? 523  GLU A OE2 1 
ATOM   4017 N  N   . THR A 1 532 ? 11.778  -23.721 37.292  1   29.229 ? 524  THR A N   1 
ATOM   4018 C  CA  . THR A 1 532 ? 12.169  -24.483 36.114  1   30.033 ? 524  THR A CA  1 
ATOM   4019 C  C   . THR A 1 532 ? 11.554  -23.914 34.842  1   30.867 ? 524  THR A C   1 
ATOM   4020 O  O   . THR A 1 532 ? 12.02   -24.247 33.761  1   30.212 ? 524  THR A O   1 
ATOM   4021 C  CB  . THR A 1 532 ? 11.849  -25.974 36.26   1   29.305 ? 524  THR A CB  1 
ATOM   4022 O  OG1 . THR A 1 532 ? 10.443  -26.131 36.366  1   29.203 ? 524  THR A OG1 1 
ATOM   4023 C  CG2 . THR A 1 532 ? 12.553  -26.643 37.433  1   33.639 ? 524  THR A CG2 1 
ATOM   4024 N  N   . LYS A 1 533 ? 10.524  -23.059 34.958  1   28.651 ? 525  LYS A N   1 
ATOM   4025 C  CA  . LYS A 1 533 ? 9.869   -22.543 33.757  1   30.5   ? 525  LYS A CA  1 
ATOM   4026 C  C   . LYS A 1 533 ? 9.952   -21.026 33.727  1   28.019 ? 525  LYS A C   1 
ATOM   4027 O  O   . LYS A 1 533 ? 9.619   -20.388 34.707  1   28.919 ? 525  LYS A O   1 
ATOM   4028 C  CB  . LYS A 1 533 ? 8.389   -22.961 33.73   1   32.55  ? 525  LYS A CB  1 
ATOM   4029 C  CG  . LYS A 1 533 ? 8.147   -24.455 33.61   1   36.602 ? 525  LYS A CG  1 
ATOM   4030 C  CD  . LYS A 1 533 ? 6.653   -24.702 33.461  1   39.568 ? 525  LYS A CD  1 
ATOM   4031 C  CE  . LYS A 1 533 ? 6.332   -26.149 33.53   1   45.531 ? 525  LYS A CE  1 
ATOM   4032 N  NZ  . LYS A 1 533 ? 4.895   -26.17  33.252  1   50.523 ? 525  LYS A NZ  1 
ATOM   4033 N  N   . GLY A 1 534 ? 10.337  -20.468 32.568  1   29.834 ? 526  GLY A N   1 
ATOM   4034 C  CA  . GLY A 1 534 ? 10.337  -19.021 32.44   1   26.301 ? 526  GLY A CA  1 
ATOM   4035 C  C   . GLY A 1 534 ? 9.123   -18.616 31.627  1   23.967 ? 526  GLY A C   1 
ATOM   4036 O  O   . GLY A 1 534 ? 8.387   -19.483 31.153  1   24.54  ? 526  GLY A O   1 
ATOM   4037 N  N   . LEU A 1 535 ? 8.976   -17.307 31.402  1   23.915 ? 527  LEU A N   1 
ATOM   4038 C  CA  . LEU A 1 535 ? 7.912   -16.815 30.526  1   23.049 ? 527  LEU A CA  1 
ATOM   4039 C  C   . LEU A 1 535 ? 8.217   -17.162 29.072  1   22.984 ? 527  LEU A C   1 
ATOM   4040 O  O   . LEU A 1 535 ? 7.323   -17.195 28.262  1   25.013 ? 527  LEU A O   1 
ATOM   4041 C  CB  . LEU A 1 535 ? 7.781   -15.296 30.666  1   21.704 ? 527  LEU A CB  1 
ATOM   4042 C  CG  . LEU A 1 535 ? 7.3     -14.8   32.028  1   21.925 ? 527  LEU A CG  1 
ATOM   4043 C  CD1 . LEU A 1 535 ? 7.19    -13.261 31.904  1   22.307 ? 527  LEU A CD1 1 
ATOM   4044 C  CD2 . LEU A 1 535 ? 5.931   -15.517 32.423  1   19.318 ? 527  LEU A CD2 1 
ATOM   4045 N  N   . VAL A 1 536 ? 9.512   -17.367 28.764  1   21.777 ? 528  VAL A N   1 
ATOM   4046 C  CA  . VAL A 1 536 ? 9.944   -17.634 27.401  1   22.319 ? 528  VAL A CA  1 
ATOM   4047 C  C   . VAL A 1 536 ? 10.655  -18.993 27.433  1   24.759 ? 528  VAL A C   1 
ATOM   4048 O  O   . VAL A 1 536 ? 11.623  -19.169 28.16   1   26.505 ? 528  VAL A O   1 
ATOM   4049 C  CB  . VAL A 1 536 ? 10.878  -16.501 26.918  1   23.972 ? 528  VAL A CB  1 
ATOM   4050 C  CG1 . VAL A 1 536 ? 11.36   -16.737 25.481  1   27.602 ? 528  VAL A CG1 1 
ATOM   4051 C  CG2 . VAL A 1 536 ? 10.22   -15.112 26.993  1   24.401 ? 528  VAL A CG2 1 
ATOM   4052 N  N   . ASP A 1 537 ? 10.226  -19.938 26.599  1   25.454 ? 529  ASP A N   1 
ATOM   4053 C  CA  . ASP A 1 537 ? 10.934  -21.219 26.574  1   28.723 ? 529  ASP A CA  1 
ATOM   4054 C  C   . ASP A 1 537 ? 12.262  -21.073 25.835  1   28.301 ? 529  ASP A C   1 
ATOM   4055 O  O   . ASP A 1 537 ? 12.312  -20.422 24.804  1   29.152 ? 529  ASP A O   1 
ATOM   4056 C  CB  . ASP A 1 537 ? 10.112  -22.33  25.951  1   33.854 ? 529  ASP A CB  1 
ATOM   4057 C  CG  . ASP A 1 537 ? 9.131   -23.017 26.887  1   45.252 ? 529  ASP A CG  1 
ATOM   4058 O  OD1 . ASP A 1 537 ? 9.274   -22.889 28.15   1   40.32  ? 529  ASP A OD1 1 
ATOM   4059 O  OD2 . ASP A 1 537 ? 8.211   -23.639 26.33   1   51.181 ? 529  ASP A OD2 1 
ATOM   4060 N  N   . LEU A 1 538 ? 13.317  -21.67  26.391  1   27.763 ? 530  LEU A N   1 
ATOM   4061 C  CA  . LEU A 1 538 ? 14.643  -21.592 25.782  1   29.867 ? 530  LEU A CA  1 
ATOM   4062 C  C   . LEU A 1 538 ? 14.656  -22.415 24.5    1   26.795 ? 530  LEU A C   1 
ATOM   4063 O  O   . LEU A 1 538 ? 14.056  -23.499 24.457  1   26.27  ? 530  LEU A O   1 
ATOM   4064 C  CB  . LEU A 1 538 ? 15.764  -22.024 26.724  1   29.274 ? 530  LEU A CB  1 
ATOM   4065 C  CG  . LEU A 1 538 ? 16.013  -21.139 27.946  1   31.327 ? 530  LEU A CG  1 
ATOM   4066 C  CD1 . LEU A 1 538 ? 17.129  -21.835 28.692  1   29.17  ? 530  LEU A CD1 1 
ATOM   4067 C  CD2 . LEU A 1 538 ? 16.351  -19.665 27.601  1   38.223 ? 530  LEU A CD2 1 
ATOM   4068 N  N   . PRO A 1 539 ? 15.393  -22.009 23.443  1   23.678 ? 531  PRO A N   1 
ATOM   4069 C  CA  . PRO A 1 539 ? 15.566  -22.909 22.302  1   23.204 ? 531  PRO A CA  1 
ATOM   4070 C  C   . PRO A 1 539 ? 16.4    -24.128 22.692  1   21.879 ? 531  PRO A C   1 
ATOM   4071 O  O   . PRO A 1 539 ? 17.024  -24.109 23.735  1   22.409 ? 531  PRO A O   1 
ATOM   4072 C  CB  . PRO A 1 539 ? 16.29   -22.066 21.247  1   25.309 ? 531  PRO A CB  1 
ATOM   4073 C  CG  . PRO A 1 539 ? 16.637  -20.776 21.913  1   23.565 ? 531  PRO A CG  1 
ATOM   4074 C  CD  . PRO A 1 539 ? 16.143  -20.739 23.333  1   24.858 ? 531  PRO A CD  1 
ATOM   4075 N  N   . LYS A 1 540 ? 16.4    -25.179 21.854  1   23.751 ? 532  LYS A N   1 
ATOM   4076 C  CA  . LYS A 1 540 ? 17.132  -26.4   22.177  1   23.604 ? 532  LYS A CA  1 
ATOM   4077 C  C   . LYS A 1 540 ? 18.642  -26.139 22.177  1   24.734 ? 532  LYS A C   1 
ATOM   4078 O  O   . LYS A 1 540 ? 19.146  -25.254 21.476  1   24.06  ? 532  LYS A O   1 
ATOM   4079 C  CB  . LYS A 1 540 ? 16.714  -27.428 21.112  1   23.297 ? 532  LYS A CB  1 
ATOM   4080 C  CG  . LYS A 1 540 ? 17.291  -27.175 19.707  1   20.444 ? 532  LYS A CG  1 
ATOM   4081 C  CD  . LYS A 1 540 ? 16.945  -28.367 18.827  1   24.887 ? 532  LYS A CD  1 
ATOM   4082 C  CE  . LYS A 1 540 ? 17.481  -28.261 17.428  1   27.174 ? 532  LYS A CE  1 
ATOM   4083 N  NZ  . LYS A 1 540 ? 17.327  -29.584 16.768  1   27.08  ? 532  LYS A NZ  1 
ATOM   4084 N  N   . GLU A 1 541 ? 19.356  -26.964 22.929  1   25.855 ? 533  GLU A N   1 
ATOM   4085 C  CA  . GLU A 1 541 ? 20.808  -26.861 22.965  1   24.687 ? 533  GLU A CA  1 
ATOM   4086 C  C   . GLU A 1 541 ? 21.461  -27.337 21.655  1   24.357 ? 533  GLU A C   1 
ATOM   4087 O  O   . GLU A 1 541 ? 22.453  -26.733 21.197  1   25.455 ? 533  GLU A O   1 
ATOM   4088 C  CB  . GLU A 1 541 ? 21.3    -27.721 24.132  1   28.364 ? 533  GLU A CB  1 
ATOM   4089 C  CG  . GLU A 1 541 ? 22.813  -27.69  24.248  1   30.894 ? 533  GLU A CG  1 
ATOM   4090 C  CD  . GLU A 1 541 ? 23.313  -28.214 25.586  1   41.091 ? 533  GLU A CD  1 
ATOM   4091 O  OE1 . GLU A 1 541 ? 22.742  -29.207 26.056  1   39.595 ? 533  GLU A OE1 1 
ATOM   4092 O  OE2 . GLU A 1 541 ? 24.288  -27.659 26.137  1   51.599 ? 533  GLU A OE2 1 
ATOM   4093 N  N   . GLU A 1 542 ? 21.033  -28.503 21.154  1   22.243 ? 534  GLU A N   1 
ATOM   4094 C  CA  . GLU A 1 542 ? 21.721  -29.123 20.018  1   23.676 ? 534  GLU A CA  1 
ATOM   4095 C  C   . GLU A 1 542 ? 21.761  -28.159 18.82   1   22.64  ? 534  GLU A C   1 
ATOM   4096 O  O   . GLU A 1 542 ? 20.793  -27.47  18.558  1   23.473 ? 534  GLU A O   1 
ATOM   4097 C  CB  . GLU A 1 542 ? 21      -30.417 19.657  1   29.205 ? 534  GLU A CB  1 
ATOM   4098 C  CG  . GLU A 1 542 ? 21.572  -31.042 18.392  1   36.215 ? 534  GLU A CG  1 
ATOM   4099 C  CD  . GLU A 1 542 ? 21.155  -32.465 18.103  1   53.065 ? 534  GLU A CD  1 
ATOM   4100 O  OE1 . GLU A 1 542 ? 19.947  -32.669 17.932  1   43.736 ? 534  GLU A OE1 1 
ATOM   4101 O  OE2 . GLU A 1 542 ? 22.04   -33.346 18.049  1   70.179 ? 534  GLU A OE2 1 
ATOM   4102 N  N   . HIS A 1 543 ? 22.92   -28.06  18.154  1   24.525 ? 535  HIS A N   1 
ATOM   4103 C  CA  . HIS A 1 543 ? 23.052  -27.242 16.955  1   23.406 ? 535  HIS A CA  1 
ATOM   4104 C  C   . HIS A 1 543 ? 22.204  -27.812 15.828  1   23.499 ? 535  HIS A C   1 
ATOM   4105 O  O   . HIS A 1 543 ? 22.131  -29.023 15.662  1   22.39  ? 535  HIS A O   1 
ATOM   4106 C  CB  . HIS A 1 543 ? 24.519  -27.122 16.55   1   22.363 ? 535  HIS A CB  1 
ATOM   4107 C  CG  . HIS A 1 543 ? 25.34   -26.368 17.544  1   24.841 ? 535  HIS A CG  1 
ATOM   4108 N  ND1 . HIS A 1 543 ? 26.579  -26.792 17.99   1   27.698 ? 535  HIS A ND1 1 
ATOM   4109 C  CD2 . HIS A 1 543 ? 25.077  -25.208 18.188  1   20.909 ? 535  HIS A CD2 1 
ATOM   4110 C  CE1 . HIS A 1 543 ? 27.077  -25.892 18.857  1   24.954 ? 535  HIS A CE1 1 
ATOM   4111 N  NE2 . HIS A 1 543 ? 26.188  -24.912 18.974  1   31.211 ? 535  HIS A NE2 1 
ATOM   4112 N  N   . TRP A 1 544 ? 21.622  -26.91  15.021  1   21.846 ? 536  TRP A N   1 
ATOM   4113 C  CA  . TRP A 1 544 ? 21.041  -27.303 13.744  1   22.105 ? 536  TRP A CA  1 
ATOM   4114 C  C   . TRP A 1 544 ? 22.115  -27.751 12.768  1   21.67  ? 536  TRP A C   1 
ATOM   4115 O  O   . TRP A 1 544 ? 21.84   -28.624 11.939  1   22.828 ? 536  TRP A O   1 
ATOM   4116 C  CB  . TRP A 1 544 ? 20.25   -26.164 13.068  1   22.917 ? 536  TRP A CB  1 
ATOM   4117 C  CG  . TRP A 1 544 ? 19.097  -25.631 13.872  1   22.423 ? 536  TRP A CG  1 
ATOM   4118 C  CD1 . TRP A 1 544 ? 19.017  -24.418 14.501  1   23.538 ? 536  TRP A CD1 1 
ATOM   4119 C  CD2 . TRP A 1 544 ? 17.83   -26.28  14.084  1   22.827 ? 536  TRP A CD2 1 
ATOM   4120 N  NE1 . TRP A 1 544 ? 17.779  -24.265 15.081  1   20.24  ? 536  TRP A NE1 1 
ATOM   4121 C  CE2 . TRP A 1 544 ? 17.041  -25.39  14.864  1   21.505 ? 536  TRP A CE2 1 
ATOM   4122 C  CE3 . TRP A 1 544 ? 17.302  -27.533 13.72   1   23.392 ? 536  TRP A CE3 1 
ATOM   4123 C  CZ2 . TRP A 1 544 ? 15.726  -25.693 15.246  1   24.511 ? 536  TRP A CZ2 1 
ATOM   4124 C  CZ3 . TRP A 1 544 ? 16.01   -27.837 14.121  1   25.147 ? 536  TRP A CZ3 1 
ATOM   4125 C  CH2 . TRP A 1 544 ? 15.227  -26.927 14.861  1   24.632 ? 536  TRP A CH2 1 
ATOM   4126 N  N   . ALA A 1 545 ? 23.281  -27.066 12.774  1   20.803 ? 537  ALA A N   1 
ATOM   4127 C  CA  . ALA A 1 545 ? 24.182  -27.255 11.648  1   21.861 ? 537  ALA A CA  1 
ATOM   4128 C  C   . ALA A 1 545 ? 25.257  -28.269 12.038  1   23.402 ? 537  ALA A C   1 
ATOM   4129 O  O   . ALA A 1 545 ? 25.683  -28.284 13.199  1   23.096 ? 537  ALA A O   1 
ATOM   4130 C  CB  . ALA A 1 545 ? 24.847  -25.923 11.329  1   18.683 ? 537  ALA A CB  1 
ATOM   4131 N  N   . PRO A 1 546 ? 25.829  -28.993 11.049  1   24.407 ? 538  PRO A N   1 
ATOM   4132 C  CA  . PRO A 1 546 ? 26.99   -29.848 11.315  1   25.706 ? 538  PRO A CA  1 
ATOM   4133 C  C   . PRO A 1 546 ? 28.258  -29.028 11.502  1   27.58  ? 538  PRO A C   1 
ATOM   4134 O  O   . PRO A 1 546 ? 28.383  -27.905 10.978  1   23.266 ? 538  PRO A O   1 
ATOM   4135 C  CB  . PRO A 1 546 ? 27.034  -30.779 10.089  1   25.717 ? 538  PRO A CB  1 
ATOM   4136 C  CG  . PRO A 1 546 ? 26.49   -29.888 8.994   1   28.454 ? 538  PRO A CG  1 
ATOM   4137 C  CD  . PRO A 1 546 ? 25.418  -29.02  9.634   1   24.478 ? 538  PRO A CD  1 
ATOM   4138 N  N   . LEU A 1 547 ? 29.225  -29.611 12.226  1   26.152 ? 539  LEU A N   1 
ATOM   4139 C  CA  . LEU A 1 547 ? 30.543  -29.012 12.412  1   26.251 ? 539  LEU A CA  1 
ATOM   4140 C  C   . LEU A 1 547 ? 31.178  -28.58  11.083  1   25.636 ? 539  LEU A C   1 
ATOM   4141 O  O   . LEU A 1 547 ? 31.738  -27.493 11.025  1   28.859 ? 539  LEU A O   1 
ATOM   4142 C  CB  . LEU A 1 547 ? 31.436  -30.023 13.153  1   27.313 ? 539  LEU A CB  1 
ATOM   4143 C  CG  . LEU A 1 547 ? 32.754  -29.452 13.692  1   30.283 ? 539  LEU A CG  1 
ATOM   4144 C  CD1 . LEU A 1 547 ? 32.52   -28.49  14.87   1   32.413 ? 539  LEU A CD1 1 
ATOM   4145 C  CD2 . LEU A 1 547 ? 33.635  -30.65  14.151  1   33.623 ? 539  LEU A CD2 1 
ATOM   4146 N  N   . SER A 1 548 ? 31.011  -29.396 10.03   1   26.925 ? 540  SER A N   1 
ATOM   4147 C  CA  . SER A 1 548 ? 31.614  -29.195 8.701   1   25.092 ? 540  SER A CA  1 
ATOM   4148 C  C   . SER A 1 548 ? 31.184  -27.895 8.025   1   26.446 ? 540  SER A C   1 
ATOM   4149 O  O   . SER A 1 548 ? 31.869  -27.425 7.121   1   25.211 ? 540  SER A O   1 
ATOM   4150 C  CB  . SER A 1 548 ? 31.358  -30.359 7.807   1   26.595 ? 540  SER A CB  1 
ATOM   4151 O  OG  . SER A 1 548 ? 29.962  -30.54  7.561   1   29.374 ? 540  SER A OG  1 
ATOM   4152 N  N   . GLN A 1 549 ? 30.066  -27.307 8.476   1   21.444 ? 541  GLN A N   1 
ATOM   4153 C  CA  . GLN A 1 549 ? 29.547  -26.072 7.891   1   22.295 ? 541  GLN A CA  1 
ATOM   4154 C  C   . GLN A 1 549 ? 30.155  -24.804 8.488   1   25.719 ? 541  GLN A C   1 
ATOM   4155 O  O   . GLN A 1 549 ? 29.924  -23.732 7.923   1   23.452 ? 541  GLN A O   1 
ATOM   4156 C  CB  . GLN A 1 549 ? 28.033  -26.058 8.032   1   19.977 ? 541  GLN A CB  1 
ATOM   4157 C  CG  . GLN A 1 549 ? 27.382  -26.951 6.969   1   17.92  ? 541  GLN A CG  1 
ATOM   4158 C  CD  . GLN A 1 549 ? 27.246  -26.309 5.613   1   20.583 ? 541  GLN A CD  1 
ATOM   4159 O  OE1 . GLN A 1 549 ? 26.661  -25.23  5.449   1   21.471 ? 541  GLN A OE1 1 
ATOM   4160 N  NE2 . GLN A 1 549 ? 27.772  -26.969 4.606   1   20.873 ? 541  GLN A NE2 1 
ATOM   4161 N  N   . SER A 1 550 ? 30.968  -24.919 9.547   1   24.902 ? 542  SER A N   1 
ATOM   4162 C  CA  . SER A 1 550 ? 31.575  -23.723 10.126  1   26.561 ? 542  SER A CA  1 
ATOM   4163 C  C   . SER A 1 550 ? 32.509  -23.07  9.114   1   22.049 ? 542  SER A C   1 
ATOM   4164 O  O   . SER A 1 550 ? 33.258  -23.78  8.445   1   21.814 ? 542  SER A O   1 
ATOM   4165 C  CB  . SER A 1 550 ? 32.389  -23.98  11.352  1   29.094 ? 542  SER A CB  1 
ATOM   4166 O  OG  . SER A 1 550 ? 32.707  -22.695 11.91   1   31.234 ? 542  SER A OG  1 
ATOM   4167 N  N   . PRO A 1 551 ? 32.46   -21.724 8.941   1   23.61  ? 543  PRO A N   1 
ATOM   4168 C  CA  . PRO A 1 551 ? 33.427  -21.048 8.085   1   20.98  ? 543  PRO A CA  1 
ATOM   4169 C  C   . PRO A 1 551 ? 34.853  -21.173 8.624   1   22.828 ? 543  PRO A C   1 
ATOM   4170 O  O   . PRO A 1 551 ? 35.796  -21.093 7.853   1   20.581 ? 543  PRO A O   1 
ATOM   4171 C  CB  . PRO A 1 551 ? 32.971  -19.586 8.044   1   22.839 ? 543  PRO A CB  1 
ATOM   4172 C  CG  . PRO A 1 551 ? 32.153  -19.439 9.301   1   23.977 ? 543  PRO A CG  1 
ATOM   4173 C  CD  . PRO A 1 551 ? 31.497  -20.779 9.56    1   24.495 ? 543  PRO A CD  1 
ATOM   4174 N  N   . TYR A 1 552 ? 34.97   -21.325 9.962   1   21.584 ? 544  TYR A N   1 
ATOM   4175 C  CA  . TYR A 1 552 ? 36.266  -21.37  10.626  1   22.958 ? 544  TYR A CA  1 
ATOM   4176 C  C   . TYR A 1 552 ? 36.842  -22.783 10.576  1   25.271 ? 544  TYR A C   1 
ATOM   4177 O  O   . TYR A 1 552 ? 36.157  -23.763 10.835  1   26.425 ? 544  TYR A O   1 
ATOM   4178 C  CB  . TYR A 1 552 ? 36.021  -20.932 12.071  1   20.932 ? 544  TYR A CB  1 
ATOM   4179 C  CG  . TYR A 1 552 ? 37.15   -21.222 13.038  1   24.863 ? 544  TYR A CG  1 
ATOM   4180 C  CD1 . TYR A 1 552 ? 38.272  -20.384 13.116  1   25.281 ? 544  TYR A CD1 1 
ATOM   4181 C  CD2 . TYR A 1 552 ? 37.067  -22.334 13.874  1   25.69  ? 544  TYR A CD2 1 
ATOM   4182 C  CE1 . TYR A 1 552 ? 39.295  -20.654 14.019  1   25.933 ? 544  TYR A CE1 1 
ATOM   4183 C  CE2 . TYR A 1 552 ? 38.073  -22.597 14.787  1   25.233 ? 544  TYR A CE2 1 
ATOM   4184 C  CZ  . TYR A 1 552 ? 39.164  -21.745 14.87   1   29.777 ? 544  TYR A CZ  1 
ATOM   4185 O  OH  . TYR A 1 552 ? 40.137  -22.05  15.773  1   32.33  ? 544  TYR A OH  1 
ATOM   4186 N  N   . ASP A 1 553 ? 38.139  -22.833 10.285  1   24.951 ? 545  ASP A N   1 
ATOM   4187 C  CA  . ASP A 1 553 ? 38.91   -24.062 10.342  1   28.281 ? 545  ASP A CA  1 
ATOM   4188 C  C   . ASP A 1 553 ? 40.056  -23.839 11.326  1   25.516 ? 545  ASP A C   1 
ATOM   4189 O  O   . ASP A 1 553 ? 40.882  -22.973 11.078  1   25.039 ? 545  ASP A O   1 
ATOM   4190 C  CB  . ASP A 1 553 ? 39.387  -24.407 8.939   1   29.958 ? 545  ASP A CB  1 
ATOM   4191 C  CG  . ASP A 1 553 ? 40.265  -25.647 8.818   1   33.172 ? 545  ASP A CG  1 
ATOM   4192 O  OD1 . ASP A 1 553 ? 40.586  -26.263 9.857   1   31.221 ? 545  ASP A OD1 1 
ATOM   4193 O  OD2 . ASP A 1 553 ? 40.637  -25.967 7.685   1   36.485 ? 545  ASP A OD2 1 
ATOM   4194 N  N   . PRO A 1 554 ? 40.165  -24.601 12.448  1   27.941 ? 546  PRO A N   1 
ATOM   4195 C  CA  . PRO A 1 554 ? 41.258  -24.408 13.394  1   29.625 ? 546  PRO A CA  1 
ATOM   4196 C  C   . PRO A 1 554 ? 42.65   -24.675 12.819  1   28.016 ? 546  PRO A C   1 
ATOM   4197 O  O   . PRO A 1 554 ? 43.605  -24.164 13.373  1   30.798 ? 546  PRO A O   1 
ATOM   4198 C  CB  . PRO A 1 554 ? 40.936  -25.326 14.571  1   32.824 ? 546  PRO A CB  1 
ATOM   4199 C  CG  . PRO A 1 554 ? 39.965  -26.333 14.003  1   32.439 ? 546  PRO A CG  1 
ATOM   4200 C  CD  . PRO A 1 554 ? 39.216  -25.647 12.892  1   31.958 ? 546  PRO A CD  1 
ATOM   4201 N  N   . ASP A 1 555 ? 42.715  -25.338 11.661  1   31.515 ? 547  ASP A N   1 
ATOM   4202 C  CA  . ASP A 1 555 ? 43.965  -25.618 10.973  1   38.309 ? 547  ASP A CA  1 
ATOM   4203 C  C   . ASP A 1 555 ? 44.361  -24.511 9.999   1   39.4   ? 547  ASP A C   1 
ATOM   4204 O  O   . ASP A 1 555 ? 45.503  -24.518 9.544   1   35.878 ? 547  ASP A O   1 
ATOM   4205 C  CB  . ASP A 1 555 ? 43.933  -26.949 10.234  1   40.333 ? 547  ASP A CB  1 
ATOM   4206 C  CG  . ASP A 1 555 ? 43.517  -28.146 11.073  1   46.421 ? 547  ASP A CG  1 
ATOM   4207 O  OD1 . ASP A 1 555 ? 44.039  -28.294 12.198  1   42.041 ? 547  ASP A OD1 1 
ATOM   4208 O  OD2 . ASP A 1 555 ? 42.637  -28.894 10.592  1   47.883 ? 547  ASP A OD2 1 
ATOM   4209 N  N   . ALA A 1 556 ? 43.435  -23.589 9.654   1   30.416 ? 548  ALA A N   1 
ATOM   4210 C  CA  . ALA A 1 556 ? 43.705  -22.584 8.625   1   30.277 ? 548  ALA A CA  1 
ATOM   4211 C  C   . ALA A 1 556 ? 44.694  -21.503 9.109   1   31.987 ? 548  ALA A C   1 
ATOM   4212 O  O   . ALA A 1 556 ? 45.261  -20.837 8.221   1   37.946 ? 548  ALA A O   1 
ATOM   4213 C  CB  . ALA A 1 556 ? 42.409  -21.956 8.157   1   29.296 ? 548  ALA A CB  1 
ATOM   4214 O  OXT . ALA A 1 556 ? 44.82   -21.297 10.33   1   30.678 ? 548  ALA A OXT 1 
ATOM   4215 N  N   . TYR B 1 32  ? 14.158  19.095  32.176  1   68.487 ? 24   TYR B N   1 
ATOM   4216 C  CA  . TYR B 1 32  ? 14.797  18.778  30.87   1   70.886 ? 24   TYR B CA  1 
ATOM   4217 C  C   . TYR B 1 32  ? 14.894  17.257  30.709  1   66.082 ? 24   TYR B C   1 
ATOM   4218 O  O   . TYR B 1 32  ? 14.527  16.735  29.66   1   70.918 ? 24   TYR B O   1 
ATOM   4219 C  CB  . TYR B 1 32  ? 16.134  19.523  30.731  1   65.002 ? 24   TYR B CB  1 
ATOM   4220 N  N   . VAL B 1 33  ? 15.415  16.559  31.736  1   56.661 ? 25   VAL B N   1 
ATOM   4221 C  CA  . VAL B 1 33  ? 15.896  15.179  31.634  1   51.883 ? 25   VAL B CA  1 
ATOM   4222 C  C   . VAL B 1 33  ? 15.192  14.332  32.697  1   47.039 ? 25   VAL B C   1 
ATOM   4223 O  O   . VAL B 1 33  ? 15.193  14.681  33.879  1   43.754 ? 25   VAL B O   1 
ATOM   4224 C  CB  . VAL B 1 33  ? 17.439  15.02   31.724  1   55.619 ? 25   VAL B CB  1 
ATOM   4225 C  CG1 . VAL B 1 33  ? 17.904  13.577  31.521  1   48.427 ? 25   VAL B CG1 1 
ATOM   4226 C  CG2 . VAL B 1 33  ? 18.201  15.937  30.766  1   60.243 ? 25   VAL B CG2 1 
ATOM   4227 N  N   . HIS B 1 34  ? 14.608  13.207  32.261  1   40.636 ? 26   HIS B N   1 
ATOM   4228 C  CA  . HIS B 1 34  ? 13.934  12.276  33.157  1   36.889 ? 26   HIS B CA  1 
ATOM   4229 C  C   . HIS B 1 34  ? 14.965  11.586  34.049  1   36.307 ? 26   HIS B C   1 
ATOM   4230 O  O   . HIS B 1 34  ? 15.947  11.047  33.527  1   34.678 ? 26   HIS B O   1 
ATOM   4231 C  CB  . HIS B 1 34  ? 13.076  11.27   32.375  1   41.427 ? 26   HIS B CB  1 
ATOM   4232 C  CG  . HIS B 1 34  ? 12.036  10.619  33.232  1   40.95  ? 26   HIS B CG  1 
ATOM   4233 N  ND1 . HIS B 1 34  ? 12.336  9.703   34.231  1   42.034 ? 26   HIS B ND1 1 
ATOM   4234 C  CD2 . HIS B 1 34  ? 10.699  10.813  33.262  1   36.009 ? 26   HIS B CD2 1 
ATOM   4235 C  CE1 . HIS B 1 34  ? 11.199  9.321   34.809  1   39.989 ? 26   HIS B CE1 1 
ATOM   4236 N  NE2 . HIS B 1 34  ? 10.199  9.996   34.252  1   34.411 ? 26   HIS B NE2 1 
ATOM   4237 N  N   . PRO B 1 35  ? 14.792  11.584  35.41   1   38.992 ? 27   PRO B N   1 
ATOM   4238 C  CA  . PRO B 1 35  ? 15.73   10.921  36.315  1   36.739 ? 27   PRO B CA  1 
ATOM   4239 C  C   . PRO B 1 35  ? 16.108  9.492   35.937  1   36.384 ? 27   PRO B C   1 
ATOM   4240 O  O   . PRO B 1 35  ? 17.271  9.139   36.02   1   34.395 ? 27   PRO B O   1 
ATOM   4241 C  CB  . PRO B 1 35  ? 15.054  10.994  37.694  1   36.525 ? 27   PRO B CB  1 
ATOM   4242 C  CG  . PRO B 1 35  ? 14.084  12.132  37.586  1   40.033 ? 27   PRO B CG  1 
ATOM   4243 C  CD  . PRO B 1 35  ? 13.727  12.304  36.144  1   39.922 ? 27   PRO B CD  1 
ATOM   4244 N  N   . THR B 1 36  ? 15.129  8.677   35.49   1   34.347 ? 28   THR B N   1 
ATOM   4245 C  CA  . THR B 1 36  ? 15.408  7.278   35.17   1   32.141 ? 28   THR B CA  1 
ATOM   4246 C  C   . THR B 1 36  ? 16.185  7.132   33.858  1   34.639 ? 28   THR B C   1 
ATOM   4247 O  O   . THR B 1 36  ? 16.773  6.082   33.622  1   33.487 ? 28   THR B O   1 
ATOM   4248 C  CB  . THR B 1 36  ? 14.14   6.413   35.17   1   28.672 ? 28   THR B CB  1 
ATOM   4249 O  OG1 . THR B 1 36  ? 13.349  6.928   34.106  1   31.094 ? 28   THR B OG1 1 
ATOM   4250 C  CG2 . THR B 1 36  ? 13.345  6.583   36.457  1   31.984 ? 28   THR B CG2 1 
ATOM   4251 N  N   . ASP B 1 37  ? 16.206  8.185   33.026  1   34.524 ? 29   ASP B N   1 
ATOM   4252 C  CA  . ASP B 1 37  ? 16.886  8.126   31.733  1   34.102 ? 29   ASP B CA  1 
ATOM   4253 C  C   . ASP B 1 37  ? 18.408  8.227   31.878  1   37.67  ? 29   ASP B C   1 
ATOM   4254 O  O   . ASP B 1 37  ? 19.105  7.888   30.93   1   37.22  ? 29   ASP B O   1 
ATOM   4255 C  CB  . ASP B 1 37  ? 16.325  9.119   30.737  1   31.095 ? 29   ASP B CB  1 
ATOM   4256 C  CG  . ASP B 1 37  ? 14.923  8.822   30.238  1   32.685 ? 29   ASP B CG  1 
ATOM   4257 O  OD1 . ASP B 1 37  ? 14.397  7.747   30.547  1   30.661 ? 29   ASP B OD1 1 
ATOM   4258 O  OD2 . ASP B 1 37  ? 14.336  9.72    29.615  1   31.162 ? 29   ASP B OD2 1 
ATOM   4259 N  N   . ILE B 1 38  ? 18.912  8.629   33.057  1   40.801 ? 30   ILE B N   1 
ATOM   4260 C  CA  . ILE B 1 38  ? 20.357  8.682   33.276  1   48.717 ? 30   ILE B CA  1 
ATOM   4261 C  C   . ILE B 1 38  ? 20.884  7.371   33.864  1   47.164 ? 30   ILE B C   1 
ATOM   4262 O  O   . ILE B 1 38  ? 22.092  7.24    34.026  1   47.701 ? 30   ILE B O   1 
ATOM   4263 C  CB  . ILE B 1 38  ? 20.822  9.941   34.042  1   46.736 ? 30   ILE B CB  1 
ATOM   4264 C  CG1 . ILE B 1 38  ? 20.44   9.896   35.543  1   50.614 ? 30   ILE B CG1 1 
ATOM   4265 C  CG2 . ILE B 1 38  ? 20.32   11.208  33.34   1   50.841 ? 30   ILE B CG2 1 
ATOM   4266 C  CD1 . ILE B 1 38  ? 21.165  10.893  36.443  1   55.994 ? 30   ILE B CD1 1 
ATOM   4267 N  N   . LEU B 1 39  ? 19.985  6.418   34.183  1   43.39  ? 31   LEU B N   1 
ATOM   4268 C  CA  . LEU B 1 39  ? 20.401  5.105   34.668  1   35.908 ? 31   LEU B CA  1 
ATOM   4269 C  C   . LEU B 1 39  ? 21.03   4.321   33.505  1   37.524 ? 31   LEU B C   1 
ATOM   4270 O  O   . LEU B 1 39  ? 20.468  4.339   32.409  1   40.427 ? 31   LEU B O   1 
ATOM   4271 C  CB  . LEU B 1 39  ? 19.241  4.342   35.322  1   37.845 ? 31   LEU B CB  1 
ATOM   4272 C  CG  . LEU B 1 39  ? 18.527  4.993   36.518  1   40.405 ? 31   LEU B CG  1 
ATOM   4273 C  CD1 . LEU B 1 39  ? 17.193  4.304   36.814  1   37.666 ? 31   LEU B CD1 1 
ATOM   4274 C  CD2 . LEU B 1 39  ? 19.376  5.108   37.799  1   42.439 ? 31   LEU B CD2 1 
ATOM   4275 N  N   . PRO B 1 40  ? 22.158  3.571   33.689  1   36.931 ? 32   PRO B N   1 
ATOM   4276 C  CA  . PRO B 1 40  ? 22.84   2.866   32.579  1   38.84  ? 32   PRO B CA  1 
ATOM   4277 C  C   . PRO B 1 40  ? 22.13   1.608   32.047  1   36.941 ? 32   PRO B C   1 
ATOM   4278 O  O   . PRO B 1 40  ? 21.491  0.925   32.838  1   30.374 ? 32   PRO B O   1 
ATOM   4279 C  CB  . PRO B 1 40  ? 24.178  2.481   33.203  1   41.348 ? 32   PRO B CB  1 
ATOM   4280 C  CG  . PRO B 1 40  ? 23.874  2.334   34.694  1   40.652 ? 32   PRO B CG  1 
ATOM   4281 C  CD  . PRO B 1 40  ? 22.806  3.355   35.002  1   41.045 ? 32   PRO B CD  1 
ATOM   4282 N  N   . SER B 1 41  ? 22.256  1.257   30.745  1   35.911 ? 33   SER B N   1 
ATOM   4283 C  CA  . SER B 1 41  ? 21.429  0.196   30.151  1   38.966 ? 33   SER B CA  1 
ATOM   4284 C  C   . SER B 1 41  ? 22.124  -1.165  30.003  1   44.27  ? 33   SER B C   1 
ATOM   4285 O  O   . SER B 1 41  ? 21.444  -2.222  29.957  1   38.544 ? 33   SER B O   1 
ATOM   4286 C  CB  . SER B 1 41  ? 20.788  0.568   28.842  1   37.282 ? 33   SER B CB  1 
ATOM   4287 O  OG  . SER B 1 41  ? 21.755  0.519   27.817  1   30.649 ? 33   SER B OG  1 
ATOM   4288 N  N   . GLY B 1 42  ? 23.457  -1.108  29.842  1   33.476 ? 34   GLY B N   1 
ATOM   4289 C  CA  . GLY B 1 42  ? 24.282  -2.252  29.481  1   28.693 ? 34   GLY B CA  1 
ATOM   4290 C  C   . GLY B 1 42  ? 24.36   -2.488  27.96   1   30.036 ? 34   GLY B C   1 
ATOM   4291 O  O   . GLY B 1 42  ? 25.038  -3.426  27.519  1   31.123 ? 34   GLY B O   1 
ATOM   4292 N  N   . TRP B 1 43  ? 23.616  -1.704  27.157  1   26.623 ? 35   TRP B N   1 
ATOM   4293 C  CA  . TRP B 1 43  ? 23.611  -1.922  25.717  1   24.936 ? 35   TRP B CA  1 
ATOM   4294 C  C   . TRP B 1 43  ? 24.656  -1.035  25.041  1   28.095 ? 35   TRP B C   1 
ATOM   4295 O  O   . TRP B 1 43  ? 24.681  0.173   25.287  1   29.98  ? 35   TRP B O   1 
ATOM   4296 C  CB  . TRP B 1 43  ? 22.229  -1.604  25.113  1   25.346 ? 35   TRP B CB  1 
ATOM   4297 C  CG  . TRP B 1 43  ? 21.315  -2.797  25.181  1   22.195 ? 35   TRP B CG  1 
ATOM   4298 C  CD1 . TRP B 1 43  ? 20.625  -3.273  26.262  1   24.117 ? 35   TRP B CD1 1 
ATOM   4299 C  CD2 . TRP B 1 43  ? 21.013  -3.672  24.083  1   23.522 ? 35   TRP B CD2 1 
ATOM   4300 N  NE1 . TRP B 1 43  ? 19.916  -4.392  25.907  1   24.12  ? 35   TRP B NE1 1 
ATOM   4301 C  CE2 . TRP B 1 43  ? 20.114  -4.651  24.581  1   23.744 ? 35   TRP B CE2 1 
ATOM   4302 C  CE3 . TRP B 1 43  ? 21.41   -3.711  22.731  1   24.22  ? 35   TRP B CE3 1 
ATOM   4303 C  CZ2 . TRP B 1 43  ? 19.623  -5.667  23.756  1   22.194 ? 35   TRP B CZ2 1 
ATOM   4304 C  CZ3 . TRP B 1 43  ? 20.888  -4.689  21.916  1   22.456 ? 35   TRP B CZ3 1 
ATOM   4305 C  CH2 . TRP B 1 43  ? 20.05   -5.664  22.441  1   20.183 ? 35   TRP B CH2 1 
ATOM   4306 N  N   . PRO B 1 44  ? 25.444  -1.563  24.076  1   29.752 ? 36   PRO B N   1 
ATOM   4307 C  CA  . PRO B 1 44  ? 26.146  -0.69   23.139  1   29.552 ? 36   PRO B CA  1 
ATOM   4308 C  C   . PRO B 1 44  ? 25.162  -0.152  22.096  1   28.26  ? 36   PRO B C   1 
ATOM   4309 O  O   . PRO B 1 44  ? 24.051  -0.677  21.961  1   28.967 ? 36   PRO B O   1 
ATOM   4310 C  CB  . PRO B 1 44  ? 27.18   -1.604  22.515  1   32.473 ? 36   PRO B CB  1 
ATOM   4311 C  CG  . PRO B 1 44  ? 26.487  -2.978  22.535  1   30.655 ? 36   PRO B CG  1 
ATOM   4312 C  CD  . PRO B 1 44  ? 25.565  -3.001  23.73   1   27.411 ? 36   PRO B CD  1 
ATOM   4313 N  N   . THR B 1 45  ? 25.577  0.858   21.331  1   28.135 ? 37   THR B N   1 
ATOM   4314 C  CA  . THR B 1 45  ? 24.779  1.32    20.2    1   27.133 ? 37   THR B CA  1 
ATOM   4315 C  C   . THR B 1 45  ? 24.701  0.209   19.154  1   30.832 ? 37   THR B C   1 
ATOM   4316 O  O   . THR B 1 45  ? 25.719  -0.194  18.593  1   31.176 ? 37   THR B O   1 
ATOM   4317 C  CB  . THR B 1 45  ? 25.308  2.617   19.592  1   29.624 ? 37   THR B CB  1 
ATOM   4318 O  OG1 . THR B 1 45  ? 25.274  3.525   20.684  1   30.017 ? 37   THR B OG1 1 
ATOM   4319 C  CG2 . THR B 1 45  ? 24.401  3.158   18.497  1   29.422 ? 37   THR B CG2 1 
ATOM   4320 N  N   . ALA B 1 46  ? 23.487  -0.297  18.915  1   28.773 ? 38   ALA B N   1 
ATOM   4321 C  CA  . ALA B 1 46  ? 23.278  -1.388  17.971  1   26.246 ? 38   ALA B CA  1 
ATOM   4322 C  C   . ALA B 1 46  ? 22.37   -0.864  16.85   1   25.064 ? 38   ALA B C   1 
ATOM   4323 O  O   . ALA B 1 46  ? 21.123  -0.897  16.965  1   24.816 ? 38   ALA B O   1 
ATOM   4324 C  CB  . ALA B 1 46  ? 22.685  -2.614  18.662  1   29.392 ? 38   ALA B CB  1 
ATOM   4325 N  N   . THR B 1 47  ? 23.016  -0.335  15.805  1   23.815 ? 39   THR B N   1 
ATOM   4326 C  CA  . THR B 1 47  ? 22.275  0.298   14.713  1   26.224 ? 39   THR B CA  1 
ATOM   4327 C  C   . THR B 1 47  ? 21.747  -0.781  13.767  1   28.916 ? 39   THR B C   1 
ATOM   4328 O  O   . THR B 1 47  ? 22.302  -1.877  13.717  1   27.37  ? 39   THR B O   1 
ATOM   4329 C  CB  . THR B 1 47  ? 23.084  1.349   13.932  1   28.31  ? 39   THR B CB  1 
ATOM   4330 O  OG1 . THR B 1 47  ? 24.003  0.594   13.129  1   27.718 ? 39   THR B OG1 1 
ATOM   4331 C  CG2 . THR B 1 47  ? 23.701  2.422   14.816  1   27.116 ? 39   THR B CG2 1 
ATOM   4332 N  N   . ASP B 1 48  ? 20.723  -0.416  12.983  1   24.885 ? 40   ASP B N   1 
ATOM   4333 C  CA  . ASP B 1 48  ? 20.37   -1.124  11.764  1   22.468 ? 40   ASP B CA  1 
ATOM   4334 C  C   . ASP B 1 48  ? 20.807  -0.256  10.574  1   23.132 ? 40   ASP B C   1 
ATOM   4335 O  O   . ASP B 1 48  ? 21.403  0.812   10.77   1   28.572 ? 40   ASP B O   1 
ATOM   4336 C  CB  . ASP B 1 48  ? 18.892  -1.483  11.794  1   23.807 ? 40   ASP B CB  1 
ATOM   4337 C  CG  . ASP B 1 48  ? 17.969  -0.274  11.901  1   29.893 ? 40   ASP B CG  1 
ATOM   4338 O  OD1 . ASP B 1 48  ? 18.157  0.681   11.112  1   27.537 ? 40   ASP B OD1 1 
ATOM   4339 O  OD2 . ASP B 1 48  ? 17.081  -0.276  12.777  1   28.854 ? 40   ASP B OD2 1 
ATOM   4340 N  N   . LEU B 1 49  ? 20.532  -0.697  9.329   1   24.424 ? 41   LEU B N   1 
ATOM   4341 C  CA  . LEU B 1 49  ? 21.041  0.03    8.165   1   27.633 ? 41   LEU B CA  1 
ATOM   4342 C  C   . LEU B 1 49  ? 20.539  1.477   8.071   1   29.37  ? 41   LEU B C   1 
ATOM   4343 O  O   . LEU B 1 49  ? 21.24   2.337   7.516   1   27.999 ? 41   LEU B O   1 
ATOM   4344 C  CB  . LEU B 1 49  ? 20.779  -0.691  6.848   1   24.963 ? 41   LEU B CB  1 
ATOM   4345 C  CG  . LEU B 1 49  ? 21.777  -1.77   6.437   1   29.46  ? 41   LEU B CG  1 
ATOM   4346 C  CD1 . LEU B 1 49  ? 21.21   -2.34   5.178   1   28.745 ? 41   LEU B CD1 1 
ATOM   4347 C  CD2 . LEU B 1 49  ? 23.177  -1.203  6.199   1   28.723 ? 41   LEU B CD2 1 
ATOM   4348 N  N   . SER B 1 50  ? 19.338  1.747   8.614   1   25.732 ? 42   SER B N   1 
ATOM   4349 C  CA  . SER B 1 50  ? 18.786  3.098   8.608   1   26.622 ? 42   SER B CA  1 
ATOM   4350 C  C   . SER B 1 50  ? 19.57   4.054   9.516   1   27.253 ? 42   SER B C   1 
ATOM   4351 O  O   . SER B 1 50  ? 19.412  5.261   9.386   1   26.776 ? 42   SER B O   1 
ATOM   4352 C  CB  . SER B 1 50  ? 17.285  3.062   8.947   1   26.514 ? 42   SER B CB  1 
ATOM   4353 O  OG  . SER B 1 50  ? 17.104  2.98    10.362  1   27.518 ? 42   SER B OG  1 
ATOM   4354 N  N   . GLY B 1 51  ? 20.368  3.525   10.451  1   26.613 ? 43   GLY B N   1 
ATOM   4355 C  CA  . GLY B 1 51  ? 21.037  4.302   11.48   1   27.958 ? 43   GLY B CA  1 
ATOM   4356 C  C   . GLY B 1 51  ? 20.262  4.304   12.795  1   27.141 ? 43   GLY B C   1 
ATOM   4357 O  O   . GLY B 1 51  ? 20.789  4.756   13.815  1   30.26  ? 43   GLY B O   1 
ATOM   4358 N  N   . GLY B 1 52  ? 19.02   3.783   12.774  1   24.792 ? 44   GLY B N   1 
ATOM   4359 C  CA  . GLY B 1 52  ? 18.189  3.641   13.972  1   26.972 ? 44   GLY B CA  1 
ATOM   4360 C  C   . GLY B 1 52  ? 18.856  2.728   14.988  1   27.323 ? 44   GLY B C   1 
ATOM   4361 O  O   . GLY B 1 52  ? 19.471  1.739   14.573  1   27.37  ? 44   GLY B O   1 
ATOM   4362 N  N   . ALA B 1 53  ? 18.76   3.058   16.293  1   24.515 ? 45   ALA B N   1 
ATOM   4363 C  CA  . ALA B 1 53  ? 19.483  2.225   17.247  1   27.525 ? 45   ALA B CA  1 
ATOM   4364 C  C   . ALA B 1 53  ? 18.591  1.645   18.351  1   28.8   ? 45   ALA B C   1 
ATOM   4365 O  O   . ALA B 1 53  ? 19.129  1.178   19.352  1   28.205 ? 45   ALA B O   1 
ATOM   4366 C  CB  . ALA B 1 53  ? 20.652  2.995   17.835  1   34.527 ? 45   ALA B CB  1 
ATOM   4367 N  N   . GLN B 1 54  ? 17.251  1.683   18.207  1   25.104 ? 46   GLN B N   1 
ATOM   4368 C  CA  . GLN B 1 54  ? 16.429  1.162   19.29   1   26.275 ? 46   GLN B CA  1 
ATOM   4369 C  C   . GLN B 1 54  ? 16.237  -0.357  19.148  1   21.275 ? 46   GLN B C   1 
ATOM   4370 O  O   . GLN B 1 54  ? 15.651  -0.789  18.159  1   24.281 ? 46   GLN B O   1 
ATOM   4371 C  CB  . GLN B 1 54  ? 15.094  1.916   19.292  1   29.922 ? 46   GLN B CB  1 
ATOM   4372 C  CG  . GLN B 1 54  ? 14.106  1.435   20.353  1   40.596 ? 46   GLN B CG  1 
ATOM   4373 C  CD  . GLN B 1 54  ? 14.636  1.435   21.776  1   52.215 ? 46   GLN B CD  1 
ATOM   4374 O  OE1 . GLN B 1 54  ? 15.323  2.367   22.218  1   50.64  ? 46   GLN B OE1 1 
ATOM   4375 N  NE2 . GLN B 1 54  ? 14.32   0.368   22.501  1   40.852 ? 46   GLN B NE2 1 
ATOM   4376 N  N   . PRO B 1 55  ? 16.694  -1.207  20.111  1   21.461 ? 47   PRO B N   1 
ATOM   4377 C  CA  . PRO B 1 55  ? 16.348  -2.635  20.109  1   20.242 ? 47   PRO B CA  1 
ATOM   4378 C  C   . PRO B 1 55  ? 14.847  -2.842  20.25   1   20.772 ? 47   PRO B C   1 
ATOM   4379 O  O   . PRO B 1 55  ? 14.191  -2.077  20.968  1   21.948 ? 47   PRO B O   1 
ATOM   4380 C  CB  . PRO B 1 55  ? 17.036  -3.201  21.345  1   20.438 ? 47   PRO B CB  1 
ATOM   4381 C  CG  . PRO B 1 55  ? 18.207  -2.215  21.514  1   22.641 ? 47   PRO B CG  1 
ATOM   4382 C  CD  . PRO B 1 55  ? 17.601  -0.859  21.218  1   21.899 ? 47   PRO B CD  1 
ATOM   4383 N  N   . ARG B 1 56  ? 14.316  -3.823  19.5    1   20.64  ? 48   ARG B N   1 
ATOM   4384 C  CA  . ARG B 1 56  ? 12.874  -4.09   19.528  1   20.844 ? 48   ARG B CA  1 
ATOM   4385 C  C   . ARG B 1 56  ? 12.692  -5.472  20.161  1   20.753 ? 48   ARG B C   1 
ATOM   4386 O  O   . ARG B 1 56  ? 12.425  -5.552  21.348  1   21.265 ? 48   ARG B O   1 
ATOM   4387 C  CB  . ARG B 1 56  ? 12.281  -3.928  18.124  1   23.01  ? 48   ARG B CB  1 
ATOM   4388 C  CG  . ARG B 1 56  ? 12.406  -2.522  17.526  1   22.882 ? 48   ARG B CG  1 
ATOM   4389 C  CD  . ARG B 1 56  ? 11.741  -1.445  18.361  1   22.896 ? 48   ARG B CD  1 
ATOM   4390 N  NE  . ARG B 1 56  ? 11.992  -0.19   17.645  1   25.396 ? 48   ARG B NE  1 
ATOM   4391 C  CZ  . ARG B 1 56  ? 11.541  1.003   18.053  1   28.561 ? 48   ARG B CZ  1 
ATOM   4392 N  NH1 . ARG B 1 56  ? 10.856  1.075   19.184  1   26.961 ? 48   ARG B NH1 1 
ATOM   4393 N  NH2 . ARG B 1 56  ? 11.851  2.094   17.353  1   27.97  ? 48   ARG B NH2 1 
ATOM   4394 N  N   . ARG B 1 57  ? 12.995  -6.525  19.381  1   20.337 ? 49   ARG B N   1 
ATOM   4395 C  CA  . ARG B 1 57  ? 13.233  -7.867  19.913  1   21.966 ? 49   ARG B CA  1 
ATOM   4396 C  C   . ARG B 1 57  ? 11.949  -8.564  20.388  1   24.275 ? 49   ARG B C   1 
ATOM   4397 O  O   . ARG B 1 57  ? 12.013  -9.609  21.025  1   25.678 ? 49   ARG B O   1 
ATOM   4398 C  CB  . ARG B 1 57  ? 14.285  -7.923  21.035  1   21.919 ? 49   ARG B CB  1 
ATOM   4399 C  CG  . ARG B 1 57  ? 15.543  -7.14   20.669  1   21.271 ? 49   ARG B CG  1 
ATOM   4400 C  CD  . ARG B 1 57  ? 16.468  -7.147  21.851  1   22.186 ? 49   ARG B CD  1 
ATOM   4401 N  NE  . ARG B 1 57  ? 15.968  -6.548  23.093  1   26.148 ? 49   ARG B NE  1 
ATOM   4402 C  CZ  . ARG B 1 57  ? 16.034  -7.066  24.326  1   24.03  ? 49   ARG B CZ  1 
ATOM   4403 N  NH1 . ARG B 1 57  ? 16.764  -8.14   24.627  1   23.69  ? 49   ARG B NH1 1 
ATOM   4404 N  NH2 . ARG B 1 57  ? 15.381  -6.43   25.274  1   23.579 ? 49   ARG B NH2 1 
ATOM   4405 N  N   . PHE B 1 58  ? 10.781  -8.055  20.005  1   21.95  ? 50   PHE B N   1 
ATOM   4406 C  CA  . PHE B 1 58  ? 9.596   -8.773  20.444  1   24.791 ? 50   PHE B CA  1 
ATOM   4407 C  C   . PHE B 1 58  ? 9.282   -9.866  19.438  1   21.959 ? 50   PHE B C   1 
ATOM   4408 O  O   . PHE B 1 58  ? 9.62    -9.802  18.251  1   20.532 ? 50   PHE B O   1 
ATOM   4409 C  CB  . PHE B 1 58  ? 8.403   -7.857  20.67   1   28.247 ? 50   PHE B CB  1 
ATOM   4410 C  CG  . PHE B 1 58  ? 8.311   -6.765  19.636  1   26.676 ? 50   PHE B CG  1 
ATOM   4411 C  CD1 . PHE B 1 58  ? 7.652   -6.949  18.417  1   32.042 ? 50   PHE B CD1 1 
ATOM   4412 C  CD2 . PHE B 1 58  ? 8.864   -5.504  19.927  1   29.757 ? 50   PHE B CD2 1 
ATOM   4413 C  CE1 . PHE B 1 58  ? 7.562   -5.872  17.522  1   34.393 ? 50   PHE B CE1 1 
ATOM   4414 C  CE2 . PHE B 1 58  ? 8.751   -4.434  19.026  1   28.541 ? 50   PHE B CE2 1 
ATOM   4415 C  CZ  . PHE B 1 58  ? 8.12    -4.625  17.834  1   26.372 ? 50   PHE B CZ  1 
ATOM   4416 N  N   . GLU B 1 59  ? 8.691   -10.927 19.974  1   19.283 ? 51   GLU B N   1 
ATOM   4417 C  CA  . GLU B 1 59  ? 8.29    -12.087 19.198  1   18.044 ? 51   GLU B CA  1 
ATOM   4418 C  C   . GLU B 1 59  ? 6.823   -12.329 19.518  1   18.388 ? 51   GLU B C   1 
ATOM   4419 O  O   . GLU B 1 59  ? 6.493   -12.588 20.672  1   18.45  ? 51   GLU B O   1 
ATOM   4420 C  CB  . GLU B 1 59  ? 9.091   -13.33  19.624  1   18.684 ? 51   GLU B CB  1 
ATOM   4421 C  CG  . GLU B 1 59  ? 10.59   -13.105 19.361  1   20.707 ? 51   GLU B CG  1 
ATOM   4422 C  CD  . GLU B 1 59  ? 11.357  -14.395 19.615  1   22.429 ? 51   GLU B CD  1 
ATOM   4423 O  OE1 . GLU B 1 59  ? 11.586  -14.751 20.785  1   22.355 ? 51   GLU B OE1 1 
ATOM   4424 O  OE2 . GLU B 1 59  ? 11.546  -15.105 18.608  1   20.272 ? 51   GLU B OE2 1 
ATOM   4425 N  N   . GLY B 1 60  ? 5.961   -12.193 18.517  1   18.366 ? 52   GLY B N   1 
ATOM   4426 C  CA  . GLY B 1 60  ? 4.561   -12.467 18.761  1   17.553 ? 52   GLY B CA  1 
ATOM   4427 C  C   . GLY B 1 60  ? 3.705   -11.966 17.614  1   19.996 ? 52   GLY B C   1 
ATOM   4428 O  O   . GLY B 1 60  ? 4.204   -11.806 16.497  1   22.877 ? 52   GLY B O   1 
ATOM   4429 N  N   . THR B 1 61  ? 2.436   -11.705 17.919  1   19.55  ? 53   THR B N   1 
ATOM   4430 C  CA  . THR B 1 61  ? 1.412   -11.52  16.882  1   19.196 ? 53   THR B CA  1 
ATOM   4431 C  C   . THR B 1 61  ? 0.489   -10.36  17.214  1   18.172 ? 53   THR B C   1 
ATOM   4432 O  O   . THR B 1 61  ? 0.304   -10.01  18.395  1   19.273 ? 53   THR B O   1 
ATOM   4433 C  CB  . THR B 1 61  ? 0.572   -12.788 16.648  1   19.835 ? 53   THR B CB  1 
ATOM   4434 O  OG1 . THR B 1 61  ? -0.123  -13.115 17.857  1   21.12  ? 53   THR B OG1 1 
ATOM   4435 C  CG2 . THR B 1 61  ? 1.396   -13.985 16.209  1   18.545 ? 53   THR B CG2 1 
ATOM   4436 N  N   . ILE B 1 62  ? -0.146  -9.869  16.14   1   17.296 ? 54   ILE B N   1 
ATOM   4437 C  CA  . ILE B 1 62  ? -1.368  -9.064  16.228  1   17.999 ? 54   ILE B CA  1 
ATOM   4438 C  C   . ILE B 1 62  ? -2.33   -9.614  15.192  1   18.149 ? 54   ILE B C   1 
ATOM   4439 O  O   . ILE B 1 62  ? -2.003  -9.696  13.996  1   20.535 ? 54   ILE B O   1 
ATOM   4440 C  CB  . ILE B 1 62  ? -1.077  -7.564  15.943  1   19.234 ? 54   ILE B CB  1 
ATOM   4441 C  CG1 . ILE B 1 62  ? -0.052  -6.96   16.925  1   20.774 ? 54   ILE B CG1 1 
ATOM   4442 C  CG2 . ILE B 1 62  ? -2.402  -6.765  15.923  1   20.056 ? 54   ILE B CG2 1 
ATOM   4443 C  CD1 . ILE B 1 62  ? 0.523   -5.624  16.455  1   20.798 ? 54   ILE B CD1 1 
ATOM   4444 N  N   . PHE B 1 63  ? -3.529  -9.95   15.666  1   19.916 ? 55   PHE B N   1 
ATOM   4445 C  CA  . PHE B 1 63  ? -4.595  -10.447 14.808  1   20.517 ? 55   PHE B CA  1 
ATOM   4446 C  C   . PHE B 1 63  ? -5.42   -9.243  14.367  1   19.475 ? 55   PHE B C   1 
ATOM   4447 O  O   . PHE B 1 63  ? -5.784  -8.42   15.215  1   19.036 ? 55   PHE B O   1 
ATOM   4448 C  CB  . PHE B 1 63  ? -5.425  -11.444 15.619  1   21.741 ? 55   PHE B CB  1 
ATOM   4449 C  CG  . PHE B 1 63  ? -6.616  -12.006 14.851  1   23.592 ? 55   PHE B CG  1 
ATOM   4450 C  CD1 . PHE B 1 63  ? -6.451  -13.12  14.024  1   25.627 ? 55   PHE B CD1 1 
ATOM   4451 C  CD2 . PHE B 1 63  ? -7.885  -11.425 14.938  1   21.745 ? 55   PHE B CD2 1 
ATOM   4452 C  CE1 . PHE B 1 63  ? -7.526  -13.66  13.319  1   26.159 ? 55   PHE B CE1 1 
ATOM   4453 C  CE2 . PHE B 1 63  ? -8.96   -11.944 14.206  1   22.716 ? 55   PHE B CE2 1 
ATOM   4454 C  CZ  . PHE B 1 63  ? -8.787  -13.07  13.399  1   23.844 ? 55   PHE B CZ  1 
ATOM   4455 N  N   . ASP B 1 64  ? -5.617  -9.132  13.041  1   18.712 ? 56   ASP B N   1 
ATOM   4456 C  CA  . ASP B 1 64  ? -6.449  -8.067  12.475  1   19.921 ? 56   ASP B CA  1 
ATOM   4457 C  C   . ASP B 1 64  ? -5.851  -6.708  12.815  1   19.966 ? 56   ASP B C   1 
ATOM   4458 O  O   . ASP B 1 64  ? -6.453  -5.872  13.51   1   19.647 ? 56   ASP B O   1 
ATOM   4459 C  CB  . ASP B 1 64  ? -7.891  -8.242  12.926  1   20.785 ? 56   ASP B CB  1 
ATOM   4460 C  CG  . ASP B 1 64  ? -8.915  -7.663  11.968  1   27.819 ? 56   ASP B CG  1 
ATOM   4461 O  OD1 . ASP B 1 64  ? -8.496  -7.214  10.872  1   27.721 ? 56   ASP B OD1 1 
ATOM   4462 O  OD2 . ASP B 1 64  ? -10.126 -7.689  12.307  1   30.29  ? 56   ASP B OD2 1 
ATOM   4463 N  N   . VAL B 1 65  ? -4.634  -6.49   12.295  1   19.521 ? 57   VAL B N   1 
ATOM   4464 C  CA  . VAL B 1 65  ? -3.894  -5.254  12.475  1   18.419 ? 57   VAL B CA  1 
ATOM   4465 C  C   . VAL B 1 65  ? -4.765  -4.087  12.013  1   20.106 ? 57   VAL B C   1 
ATOM   4466 O  O   . VAL B 1 65  ? -5.405  -4.146  10.955  1   21.305 ? 57   VAL B O   1 
ATOM   4467 C  CB  . VAL B 1 65  ? -2.571  -5.324  11.683  1   18.937 ? 57   VAL B CB  1 
ATOM   4468 C  CG1 . VAL B 1 65  ? -1.72   -4.08   11.931  1   18.211 ? 57   VAL B CG1 1 
ATOM   4469 C  CG2 . VAL B 1 65  ? -1.768  -6.602  12.012  1   18.806 ? 57   VAL B CG2 1 
ATOM   4470 N  N   . MET B 1 66  ? -4.713  -2.995  12.774  1   21.12  ? 58   MET B N   1 
ATOM   4471 C  CA  . MET B 1 66  ? -5.479  -1.788  12.43   1   23.751 ? 58   MET B CA  1 
ATOM   4472 C  C   . MET B 1 66  ? -5.089  -1.3    11.033  1   23.988 ? 58   MET B C   1 
ATOM   4473 O  O   . MET B 1 66  ? -3.912  -1.327  10.667  1   21.818 ? 58   MET B O   1 
ATOM   4474 C  CB  . MET B 1 66  ? -5.179  -0.643  13.402  1   22.796 ? 58   MET B CB  1 
ATOM   4475 C  CG  . MET B 1 66  ? -5.68   -0.904  14.806  1   30.433 ? 58   MET B CG  1 
ATOM   4476 S  SD  . MET B 1 66  ? -5.146  0.491   15.826  1   35.105 ? 58   MET B SD  1 
ATOM   4477 C  CE  . MET B 1 66  ? -6.338  1.704   15.209  1   32.061 ? 58   MET B CE  1 
ATOM   4478 N  N   . THR B 1 67  ? -6.097  -0.925  10.224  1   20.223 ? 59   THR B N   1 
ATOM   4479 C  CA  . THR B 1 67  ? -5.822  -0.401  8.891   1   22.242 ? 59   THR B CA  1 
ATOM   4480 C  C   . THR B 1 67  ? -6.499  0.965   8.727   1   26.854 ? 59   THR B C   1 
ATOM   4481 O  O   . THR B 1 67  ? -7.444  1.298   9.454   1   31.012 ? 59   THR B O   1 
ATOM   4482 C  CB  . THR B 1 67  ? -6.179  -1.406  7.793   1   23.465 ? 59   THR B CB  1 
ATOM   4483 O  OG1 . THR B 1 67  ? -7.605  -1.515  7.876   1   31.287 ? 59   THR B OG1 1 
ATOM   4484 C  CG2 . THR B 1 67  ? -5.446  -2.73   7.919   1   22.798 ? 59   THR B CG2 1 
ATOM   4485 N  N   . ARG B 1 68  ? -5.913  1.816   7.883   1   23.309 ? 60   ARG B N   1 
ATOM   4486 C  CA  . ARG B 1 68  ? -6.545  3.052   7.442   1   25.313 ? 60   ARG B CA  1 
ATOM   4487 C  C   . ARG B 1 68  ? -6.75   2.879   5.933   1   26.812 ? 60   ARG B C   1 
ATOM   4488 O  O   . ARG B 1 68  ? -5.876  2.327   5.261   1   26.562 ? 60   ARG B O   1 
ATOM   4489 C  CB  . ARG B 1 68  ? -5.659  4.252   7.792   1   26.543 ? 60   ARG B CB  1 
ATOM   4490 C  CG  . ARG B 1 68  ? -5.383  4.478   9.28    1   26.73  ? 60   ARG B CG  1 
ATOM   4491 C  CD  . ARG B 1 68  ? -4.739  5.825   9.59    1   25.17  ? 60   ARG B CD  1 
ATOM   4492 N  NE  . ARG B 1 68  ? -3.528  6.136   8.813   1   30.994 ? 60   ARG B NE  1 
ATOM   4493 C  CZ  . ARG B 1 68  ? -2.297  5.656   9.063   1   30.888 ? 60   ARG B CZ  1 
ATOM   4494 N  NH1 . ARG B 1 68  ? -2.111  4.768   10.053  1   25.719 ? 60   ARG B NH1 1 
ATOM   4495 N  NH2 . ARG B 1 68  ? -1.287  6.068   8.303   1   28.149 ? 60   ARG B NH2 1 
ATOM   4496 N  N   . GLY B 1 69  ? -7.918  3.283   5.424   1   26.361 ? 61   GLY B N   1 
ATOM   4497 C  CA  . GLY B 1 69  ? -8.258  3.094   4.013   1   26.066 ? 61   GLY B CA  1 
ATOM   4498 C  C   . GLY B 1 69  ? -8.731  1.684   3.738   1   28.122 ? 61   GLY B C   1 
ATOM   4499 O  O   . GLY B 1 69  ? -9.147  0.993   4.649   1   33.914 ? 61   GLY B O   1 
ATOM   4500 N  N   . THR B 1 70  ? -8.691  1.267   2.47    1   31.156 ? 62   THR B N   1 
ATOM   4501 C  CA  . THR B 1 70  ? -9.246  -0.021  2.072   1   33.188 ? 62   THR B CA  1 
ATOM   4502 C  C   . THR B 1 70  ? -8.097  -0.939  1.638   1   28.544 ? 62   THR B C   1 
ATOM   4503 O  O   . THR B 1 70  ? -7.415  -0.649  0.649   1   30.123 ? 62   THR B O   1 
ATOM   4504 C  CB  . THR B 1 70  ? -10.264 0.138   0.934   1   35.009 ? 62   THR B CB  1 
ATOM   4505 O  OG1 . THR B 1 70  ? -11.292 0.968   1.467   1   42.106 ? 62   THR B OG1 1 
ATOM   4506 C  CG2 . THR B 1 70  ? -10.919 -1.187  0.584   1   34.883 ? 62   THR B CG2 1 
ATOM   4507 N  N   . ILE B 1 71  ? -7.985  -2.094  2.293   1   27.668 ? 63   ILE B N   1 
ATOM   4508 C  CA  . ILE B 1 71  ? -7.043  -3.125  1.866   1   28.569 ? 63   ILE B CA  1 
ATOM   4509 C  C   . ILE B 1 71  ? -7.596  -3.787  0.601   1   28.581 ? 63   ILE B C   1 
ATOM   4510 O  O   . ILE B 1 71  ? -8.691  -4.353  0.656   1   28.095 ? 63   ILE B O   1 
ATOM   4511 C  CB  . ILE B 1 71  ? -6.797  -4.151  2.983   1   26.74  ? 63   ILE B CB  1 
ATOM   4512 C  CG1 . ILE B 1 71  ? -6.205  -3.487  4.272   1   28.758 ? 63   ILE B CG1 1 
ATOM   4513 C  CG2 . ILE B 1 71  ? -5.99   -5.367  2.488   1   26.954 ? 63   ILE B CG2 1 
ATOM   4514 C  CD1 . ILE B 1 71  ? -4.841  -2.845  4.098   1   27.002 ? 63   ILE B CD1 1 
ATOM   4515 N  N   . PRO B 1 72  ? -6.873  -3.762  -0.539  1   27.542 ? 64   PRO B N   1 
ATOM   4516 C  CA  . PRO B 1 72  ? -7.35   -4.431  -1.745  1   28.607 ? 64   PRO B CA  1 
ATOM   4517 C  C   . PRO B 1 72  ? -7.672  -5.897  -1.497  1   28.633 ? 64   PRO B C   1 
ATOM   4518 O  O   . PRO B 1 72  ? -6.84   -6.626  -0.959  1   25.603 ? 64   PRO B O   1 
ATOM   4519 C  CB  . PRO B 1 72  ? -6.176  -4.263  -2.736  1   26.924 ? 64   PRO B CB  1 
ATOM   4520 C  CG  . PRO B 1 72  ? -5.458  -3.045  -2.262  1   27.228 ? 64   PRO B CG  1 
ATOM   4521 C  CD  . PRO B 1 72  ? -5.585  -3.059  -0.75   1   27.188 ? 64   PRO B CD  1 
ATOM   4522 N  N   . LYS B 1 73  ? -8.878  -6.336  -1.908  1   28.975 ? 65   LYS B N   1 
ATOM   4523 C  CA  . LYS B 1 73  ? -9.2    -7.756  -1.868  1   31.07  ? 65   LYS B CA  1 
ATOM   4524 C  C   . LYS B 1 73  ? -8.317  -8.611  -2.783  1   26.214 ? 65   LYS B C   1 
ATOM   4525 O  O   . LYS B 1 73  ? -8.222  -9.81   -2.555  1   28.661 ? 65   LYS B O   1 
ATOM   4526 C  CB  . LYS B 1 73  ? -10.653 -8.05   -2.282  1   38.337 ? 65   LYS B CB  1 
ATOM   4527 C  CG  . LYS B 1 73  ? -11.696 -7.666  -1.238  1   49.781 ? 65   LYS B CG  1 
ATOM   4528 C  CD  . LYS B 1 73  ? -11.713 -8.508  0.03    1   56.851 ? 65   LYS B CD  1 
ATOM   4529 C  CE  . LYS B 1 73  ? -12.643 -7.977  1.089   1   63.838 ? 65   LYS B CE  1 
ATOM   4530 N  NZ  . LYS B 1 73  ? -14.07  -8.068  0.77    1   58.484 ? 65   LYS B NZ  1 
ATOM   4531 N  N   . GLU B 1 74  ? -7.655  -7.998  -3.769  1   28.141 ? 66   GLU B N   1 
ATOM   4532 C  CA  . GLU B 1 74  ? -6.736  -8.709  -4.661  1   31.693 ? 66   GLU B CA  1 
ATOM   4533 C  C   . GLU B 1 74  ? -5.47   -9.195  -3.94   1   29.365 ? 66   GLU B C   1 
ATOM   4534 O  O   . GLU B 1 74  ? -4.793  -10.108 -4.423  1   26.227 ? 66   GLU B O   1 
ATOM   4535 C  CB  . GLU B 1 74  ? -6.293  -7.869  -5.853  1   31.57  ? 66   GLU B CB  1 
ATOM   4536 C  CG  . GLU B 1 74  ? -7.483  -7.469  -6.731  1   32.956 ? 66   GLU B CG  1 
ATOM   4537 C  CD  . GLU B 1 74  ? -8.194  -6.177  -6.332  1   40.042 ? 66   GLU B CD  1 
ATOM   4538 O  OE1 . GLU B 1 74  ? -8.134  -5.656  -5.193  1   34.265 ? 66   GLU B OE1 1 
ATOM   4539 O  OE2 . GLU B 1 74  ? -8.765  -5.599  -7.28   1   46.154 ? 66   GLU B OE2 1 
ATOM   4540 N  N   . LEU B 1 75  ? -5.157  -8.606  -2.775  1   26.142 ? 67   LEU B N   1 
ATOM   4541 C  CA  . LEU B 1 75  ? -3.986  -9.084  -2.026  1   24.882 ? 67   LEU B CA  1 
ATOM   4542 C  C   . LEU B 1 75  ? -4.291  -10.418 -1.366  1   25.66  ? 67   LEU B C   1 
ATOM   4543 O  O   . LEU B 1 75  ? -5.19   -10.491 -0.519  1   23.86  ? 67   LEU B O   1 
ATOM   4544 C  CB  . LEU B 1 75  ? -3.451  -8.058  -1.021  1   23.023 ? 67   LEU B CB  1 
ATOM   4545 C  CG  . LEU B 1 75  ? -2.861  -6.794  -1.647  1   24.425 ? 67   LEU B CG  1 
ATOM   4546 C  CD1 . LEU B 1 75  ? -2.731  -5.706  -0.59   1   24.387 ? 67   LEU B CD1 1 
ATOM   4547 C  CD2 . LEU B 1 75  ? -1.513  -7.095  -2.275  1   22.207 ? 67   LEU B CD2 1 
ATOM   4548 N  N   . HIS B 1 76  ? -3.508  -11.452 -1.737  1   22.132 ? 68   HIS B N   1 
ATOM   4549 C  CA  . HIS B 1 76  ? -3.712  -12.802 -1.24   1   23.088 ? 68   HIS B CA  1 
ATOM   4550 C  C   . HIS B 1 76  ? -2.346  -13.438 -1.047  1   22.551 ? 68   HIS B C   1 
ATOM   4551 O  O   . HIS B 1 76  ? -1.804  -14.073 -1.94   1   23.107 ? 68   HIS B O   1 
ATOM   4552 C  CB  . HIS B 1 76  ? -4.658  -13.573 -2.192  1   24.932 ? 68   HIS B CB  1 
ATOM   4553 C  CG  . HIS B 1 76  ? -5.037  -14.945 -1.726  1   28.789 ? 68   HIS B CG  1 
ATOM   4554 N  ND1 . HIS B 1 76  ? -6.105  -15.106 -0.865  1   34.384 ? 68   HIS B ND1 1 
ATOM   4555 C  CD2 . HIS B 1 76  ? -4.562  -16.177 -1.955  1   28.714 ? 68   HIS B CD2 1 
ATOM   4556 C  CE1 . HIS B 1 76  ? -6.268  -16.391 -0.595  1   34.66  ? 68   HIS B CE1 1 
ATOM   4557 N  NE2 . HIS B 1 76  ? -5.339  -17.053 -1.231  1   30.904 ? 68   HIS B NE2 1 
ATOM   4558 N  N   . GLY B 1 77  ? -1.761  -13.247 0.151   1   21.163 ? 69   GLY B N   1 
ATOM   4559 C  CA  . GLY B 1 77  ? -0.369  -13.649 0.287   1   20.699 ? 69   GLY B CA  1 
ATOM   4560 C  C   . GLY B 1 77  ? 0.232   -12.992 1.516   1   20.366 ? 69   GLY B C   1 
ATOM   4561 O  O   . GLY B 1 77  ? -0.503  -12.502 2.389   1   20.311 ? 69   GLY B O   1 
ATOM   4562 N  N   . THR B 1 78  ? 1.568   -13.024 1.592   1   21.069 ? 70   THR B N   1 
ATOM   4563 C  CA  . THR B 1 78  ? 2.226   -12.565 2.818   1   20.42  ? 70   THR B CA  1 
ATOM   4564 C  C   . THR B 1 78  ? 3.383   -11.673 2.391   1   20.172 ? 70   THR B C   1 
ATOM   4565 O  O   . THR B 1 78  ? 4.149   -12.071 1.534   1   22.783 ? 70   THR B O   1 
ATOM   4566 C  CB  . THR B 1 78  ? 2.76    -13.726 3.653   1   20.79  ? 70   THR B CB  1 
ATOM   4567 O  OG1 . THR B 1 78  ? 1.765   -14.727 3.805   1   20.147 ? 70   THR B OG1 1 
ATOM   4568 C  CG2 . THR B 1 78  ? 3.136   -13.297 5.075   1   22.168 ? 70   THR B CG2 1 
ATOM   4569 N  N   . PHE B 1 79  ? 3.52    -10.51  3.039   1   18.879 ? 71   PHE B N   1 
ATOM   4570 C  CA  . PHE B 1 79  ? 4.693   -9.661  2.914   1   18.018 ? 71   PHE B CA  1 
ATOM   4571 C  C   . PHE B 1 79  ? 5.568   -10.037 4.1     1   18.887 ? 71   PHE B C   1 
ATOM   4572 O  O   . PHE B 1 79  ? 5.202   -9.775  5.226   1   19.259 ? 71   PHE B O   1 
ATOM   4573 C  CB  . PHE B 1 79  ? 4.252   -8.202  2.986   1   19.678 ? 71   PHE B CB  1 
ATOM   4574 C  CG  . PHE B 1 79  ? 5.355   -7.137  2.945   1   19.831 ? 71   PHE B CG  1 
ATOM   4575 C  CD1 . PHE B 1 79  ? 6.616   -7.391  2.373   1   20.723 ? 71   PHE B CD1 1 
ATOM   4576 C  CD2 . PHE B 1 79  ? 5.051   -5.823  3.309   1   19.801 ? 71   PHE B CD2 1 
ATOM   4577 C  CE1 . PHE B 1 79  ? 7.602   -6.384  2.306   1   20.5   ? 71   PHE B CE1 1 
ATOM   4578 C  CE2 . PHE B 1 79  ? 6.023   -4.815  3.193   1   22.236 ? 71   PHE B CE2 1 
ATOM   4579 C  CZ  . PHE B 1 79  ? 7.295   -5.092  2.694   1   20.862 ? 71   PHE B CZ  1 
ATOM   4580 N  N   . TYR B 1 80  ? 6.673   -10.716 3.803   1   19.29  ? 72   TYR B N   1 
ATOM   4581 C  CA  . TYR B 1 80  ? 7.618   -11.114 4.82    1   20.101 ? 72   TYR B CA  1 
ATOM   4582 C  C   . TYR B 1 80  ? 8.782   -10.149 4.741   1   22.152 ? 72   TYR B C   1 
ATOM   4583 O  O   . TYR B 1 80  ? 9.258   -9.888  3.652   1   22.936 ? 72   TYR B O   1 
ATOM   4584 C  CB  . TYR B 1 80  ? 8.187   -12.515 4.597   1   17.275 ? 72   TYR B CB  1 
ATOM   4585 C  CG  . TYR B 1 80  ? 7.234   -13.686 4.777   1   18.65  ? 72   TYR B CG  1 
ATOM   4586 C  CD1 . TYR B 1 80  ? 7.012   -14.22  6.042   1   17.202 ? 72   TYR B CD1 1 
ATOM   4587 C  CD2 . TYR B 1 80  ? 6.594   -14.258 3.689   1   20.497 ? 72   TYR B CD2 1 
ATOM   4588 C  CE1 . TYR B 1 80  ? 6.148   -15.301 6.225   1   19.011 ? 72   TYR B CE1 1 
ATOM   4589 C  CE2 . TYR B 1 80  ? 5.734   -15.346 3.852   1   21.976 ? 72   TYR B CE2 1 
ATOM   4590 C  CZ  . TYR B 1 80  ? 5.495   -15.858 5.124   1   23.676 ? 72   TYR B CZ  1 
ATOM   4591 O  OH  . TYR B 1 80  ? 4.645   -16.938 5.277   1   21.86  ? 72   TYR B OH  1 
ATOM   4592 N  N   . ARG B 1 81  ? 9.193   -9.623  5.902   1   17.772 ? 73   ARG B N   1 
ATOM   4593 C  CA  . ARG B 1 81  ? 10.327  -8.724  5.923   1   19.513 ? 73   ARG B CA  1 
ATOM   4594 C  C   . ARG B 1 81  ? 11.325  -9.254  6.952   1   18.223 ? 73   ARG B C   1 
ATOM   4595 O  O   . ARG B 1 81  ? 10.907  -9.842  7.944   1   23.48  ? 73   ARG B O   1 
ATOM   4596 C  CB  . ARG B 1 81  ? 9.746   -7.42   6.452   1   24.099 ? 73   ARG B CB  1 
ATOM   4597 C  CG  . ARG B 1 81  ? 10.596  -6.236  6.056   1   32.592 ? 73   ARG B CG  1 
ATOM   4598 C  CD  . ARG B 1 81  ? 10.252  -5.447  4.833   1   23.179 ? 73   ARG B CD  1 
ATOM   4599 N  NE  . ARG B 1 81  ? 11.171  -4.381  5.248   1   23.533 ? 73   ARG B NE  1 
ATOM   4600 C  CZ  . ARG B 1 81  ? 12.328  -4.139  4.634   1   20.237 ? 73   ARG B CZ  1 
ATOM   4601 N  NH1 . ARG B 1 81  ? 12.596  -4.67   3.443   1   19.439 ? 73   ARG B NH1 1 
ATOM   4602 N  NH2 . ARG B 1 81  ? 13.201  -3.357  5.238   1   23.495 ? 73   ARG B NH2 1 
ATOM   4603 N  N   . ILE B 1 82  ? 12.62   -9.013  6.731   1   17.783 ? 74   ILE B N   1 
ATOM   4604 C  CA  . ILE B 1 82  ? 13.596  -9.543  7.68    1   17.282 ? 74   ILE B CA  1 
ATOM   4605 C  C   . ILE B 1 82  ? 14.494  -8.389  8.113   1   17.711 ? 74   ILE B C   1 
ATOM   4606 O  O   . ILE B 1 82  ? 14.767  -7.489  7.321   1   18.934 ? 74   ILE B O   1 
ATOM   4607 C  CB  . ILE B 1 82  ? 14.349  -10.758 7.131   1   18.657 ? 74   ILE B CB  1 
ATOM   4608 C  CG1 . ILE B 1 82  ? 15.151  -11.516 8.21    1   18.241 ? 74   ILE B CG1 1 
ATOM   4609 C  CG2 . ILE B 1 82  ? 15.229  -10.394 5.916   1   18.033 ? 74   ILE B CG2 1 
ATOM   4610 C  CD1 . ILE B 1 82  ? 15.603  -12.896 7.711   1   20.488 ? 74   ILE B CD1 1 
ATOM   4611 N  N   . MET B 1 83  ? 14.828  -8.393  9.408   1   18.259 ? 75   MET B N   1 
ATOM   4612 C  CA  . MET B 1 83  ? 15.522  -7.282  10.02   1   17.086 ? 75   MET B CA  1 
ATOM   4613 C  C   . MET B 1 83  ? 16.649  -7.803  10.912  1   18.6   ? 75   MET B C   1 
ATOM   4614 O  O   . MET B 1 83  ? 16.51   -8.857  11.528  1   19.038 ? 75   MET B O   1 
ATOM   4615 C  CB  . MET B 1 83  ? 14.575  -6.514  10.955  1   19.014 ? 75   MET B CB  1 
ATOM   4616 C  CG  . MET B 1 83  ? 13.478  -5.783  10.204  1   22.386 ? 75   MET B CG  1 
ATOM   4617 S  SD  . MET B 1 83  ? 11.901  -5.901  11.096  1   27.442 ? 75   MET B SD  1 
ATOM   4618 C  CE  . MET B 1 83  ? 11.454  -7.532  10.573  1   23.37  ? 75   MET B CE  1 
ATOM   4619 N  N   . PRO B 1 84  ? 17.753  -7.043  11.054  1   18.627 ? 76   PRO B N   1 
ATOM   4620 C  CA  . PRO B 1 84  ? 18.719  -7.32   12.112  1   18.826 ? 76   PRO B CA  1 
ATOM   4621 C  C   . PRO B 1 84  ? 18.25   -6.716  13.429  1   19.262 ? 76   PRO B C   1 
ATOM   4622 O  O   . PRO B 1 84  ? 17.918  -5.534  13.489  1   20.867 ? 76   PRO B O   1 
ATOM   4623 C  CB  . PRO B 1 84  ? 19.977  -6.59   11.601  1   19.589 ? 76   PRO B CB  1 
ATOM   4624 C  CG  . PRO B 1 84  ? 19.405  -5.359  10.845  1   21.584 ? 76   PRO B CG  1 
ATOM   4625 C  CD  . PRO B 1 84  ? 18.024  -5.782  10.322  1   20.613 ? 76   PRO B CD  1 
ATOM   4626 N  N   . ASP B 1 85  ? 18.239  -7.514  14.495  1   18.713 ? 77   ASP B N   1 
ATOM   4627 C  CA  . ASP B 1 85  ? 17.778  -6.984  15.771  1   20.766 ? 77   ASP B CA  1 
ATOM   4628 C  C   . ASP B 1 85  ? 18.46   -7.825  16.828  1   20.411 ? 77   ASP B C   1 
ATOM   4629 O  O   . ASP B 1 85  ? 17.879  -8.769  17.349  1   22.033 ? 77   ASP B O   1 
ATOM   4630 C  CB  . ASP B 1 85  ? 16.268  -7.17   15.903  1   20.441 ? 77   ASP B CB  1 
ATOM   4631 C  CG  . ASP B 1 85  ? 15.481  -6.278  16.884  1   23.335 ? 77   ASP B CG  1 
ATOM   4632 O  OD1 . ASP B 1 85  ? 16.092  -5.408  17.57   1   22.459 ? 77   ASP B OD1 1 
ATOM   4633 O  OD2 . ASP B 1 85  ? 14.212  -6.448  16.918  1   25.371 ? 77   ASP B OD2 1 
ATOM   4634 N  N   . TYR B 1 86  ? 19.69   -7.467  17.181  1   20.884 ? 78   TYR B N   1 
ATOM   4635 C  CA  . TYR B 1 86  ? 20.416  -8.248  18.173  1   20.708 ? 78   TYR B CA  1 
ATOM   4636 C  C   . TYR B 1 86  ? 19.529  -8.582  19.375  1   22.643 ? 78   TYR B C   1 
ATOM   4637 O  O   . TYR B 1 86  ? 18.926  -7.694  19.969  1   20.736 ? 78   TYR B O   1 
ATOM   4638 C  CB  . TYR B 1 86  ? 21.575  -7.402  18.688  1   20.319 ? 78   TYR B CB  1 
ATOM   4639 C  CG  . TYR B 1 86  ? 22.885  -7.631  17.941  1   21.717 ? 78   TYR B CG  1 
ATOM   4640 C  CD1 . TYR B 1 86  ? 23.499  -8.887  17.973  1   20.813 ? 78   TYR B CD1 1 
ATOM   4641 C  CD2 . TYR B 1 86  ? 23.514  -6.58   17.267  1   22.383 ? 78   TYR B CD2 1 
ATOM   4642 C  CE1 . TYR B 1 86  ? 24.752  -9.081  17.399  1   20.838 ? 78   TYR B CE1 1 
ATOM   4643 C  CE2 . TYR B 1 86  ? 24.758  -6.763  16.666  1   24.6   ? 78   TYR B CE2 1 
ATOM   4644 C  CZ  . TYR B 1 86  ? 25.365  -8.01   16.754  1   23.005 ? 78   TYR B CZ  1 
ATOM   4645 O  OH  . TYR B 1 86  ? 26.614  -8.144  16.261  1   25.005 ? 78   TYR B OH  1 
ATOM   4646 N  N   . ALA B 1 87  ? 19.411  -9.887  19.663  1   17.309 ? 79   ALA B N   1 
ATOM   4647 C  CA  . ALA B 1 87  ? 18.526  -10.383 20.703  1   18.259 ? 79   ALA B CA  1 
ATOM   4648 C  C   . ALA B 1 87  ? 19.103  -10.153 22.091  1   18.788 ? 79   ALA B C   1 
ATOM   4649 O  O   . ALA B 1 87  ? 18.36   -9.961  23.048  1   20.089 ? 79   ALA B O   1 
ATOM   4650 C  CB  . ALA B 1 87  ? 18.264  -11.845 20.46   1   20.106 ? 79   ALA B CB  1 
ATOM   4651 N  N   . GLN B 1 88  ? 20.443  -10.223 22.196  1   20.513 ? 80   GLN B N   1 
ATOM   4652 C  CA  . GLN B 1 88  ? 21.143  -9.929  23.443  1   20.962 ? 80   GLN B CA  1 
ATOM   4653 C  C   . GLN B 1 88  ? 22.065  -8.738  23.165  1   21.837 ? 80   GLN B C   1 
ATOM   4654 O  O   . GLN B 1 88  ? 22.518  -8.57   22.029  1   20.522 ? 80   GLN B O   1 
ATOM   4655 C  CB  . GLN B 1 88  ? 22.005  -11.149 23.825  1   20.51  ? 80   GLN B CB  1 
ATOM   4656 C  CG  . GLN B 1 88  ? 21.222  -12.399 24.294  1   19.085 ? 80   GLN B CG  1 
ATOM   4657 C  CD  . GLN B 1 88  ? 20.231  -12.155 25.421  1   23.184 ? 80   GLN B CD  1 
ATOM   4658 O  OE1 . GLN B 1 88  ? 19.034  -12.46  25.308  1   23.452 ? 80   GLN B OE1 1 
ATOM   4659 N  NE2 . GLN B 1 88  ? 20.678  -11.54  26.508  1   22.677 ? 80   GLN B NE2 1 
ATOM   4660 N  N   . PRO B 1 89  ? 22.444  -7.913  24.173  1   19.846 ? 81   PRO B N   1 
ATOM   4661 C  CA  . PRO B 1 89  ? 23.39   -6.828  23.92   1   21.124 ? 81   PRO B CA  1 
ATOM   4662 C  C   . PRO B 1 89  ? 24.72   -7.37   23.419  1   19.637 ? 81   PRO B C   1 
ATOM   4663 O  O   . PRO B 1 89  ? 25.224  -8.321  24.02   1   22.356 ? 81   PRO B O   1 
ATOM   4664 C  CB  . PRO B 1 89  ? 23.529  -6.089  25.257  1   22.242 ? 81   PRO B CB  1 
ATOM   4665 C  CG  . PRO B 1 89  ? 22.917  -6.989  26.274  1   23.054 ? 81   PRO B CG  1 
ATOM   4666 C  CD  . PRO B 1 89  ? 21.995  -8.012  25.573  1   19.605 ? 81   PRO B CD  1 
ATOM   4667 N  N   . PRO B 1 90  ? 25.21   -6.969  22.216  1   22.804 ? 82   PRO B N   1 
ATOM   4668 C  CA  . PRO B 1 90  ? 26.309  -7.704  21.568  1   20.055 ? 82   PRO B CA  1 
ATOM   4669 C  C   . PRO B 1 90  ? 27.697  -7.352  22.105  1   20.326 ? 82   PRO B C   1 
ATOM   4670 O  O   . PRO B 1 90  ? 28.549  -6.905  21.349  1   23.93  ? 82   PRO B O   1 
ATOM   4671 C  CB  . PRO B 1 90  ? 26.118  -7.345  20.097  1   22.385 ? 82   PRO B CB  1 
ATOM   4672 C  CG  . PRO B 1 90  ? 25.561  -5.946  20.2    1   21.534 ? 82   PRO B CG  1 
ATOM   4673 C  CD  . PRO B 1 90  ? 24.621  -5.957  21.323  1   20.773 ? 82   PRO B CD  1 
ATOM   4674 N  N   . THR B 1 91  ? 27.898  -7.58   23.403  1   22.75  ? 83   THR B N   1 
ATOM   4675 C  CA  . THR B 1 91  ? 29      -6.962  24.123  1   22.34  ? 83   THR B CA  1 
ATOM   4676 C  C   . THR B 1 91  ? 30.241  -7.857  24.136  1   24.886 ? 83   THR B C   1 
ATOM   4677 O  O   . THR B 1 91  ? 31.222  -7.434  24.746  1   27.895 ? 83   THR B O   1 
ATOM   4678 C  CB  . THR B 1 91  ? 28.575  -6.664  25.563  1   23.665 ? 83   THR B CB  1 
ATOM   4679 O  OG1 . THR B 1 91  ? 28.079  -7.913  26.033  1   25.437 ? 83   THR B OG1 1 
ATOM   4680 C  CG2 . THR B 1 91  ? 27.565  -5.547  25.648  1   28.486 ? 83   THR B CG2 1 
ATOM   4681 N  N   . TYR B 1 92  ? 30.229  -9.039  23.483  1   21.344 ? 84   TYR B N   1 
ATOM   4682 C  CA  . TYR B 1 92  ? 31.324  -9.998  23.633  1   24.502 ? 84   TYR B CA  1 
ATOM   4683 C  C   . TYR B 1 92  ? 32.686  -9.387  23.271  1   26.101 ? 84   TYR B C   1 
ATOM   4684 O  O   . TYR B 1 92  ? 33.657  -9.492  24.041  1   25.701 ? 84   TYR B O   1 
ATOM   4685 C  CB  . TYR B 1 92  ? 31.101  -11.332 22.899  1   21.053 ? 84   TYR B CB  1 
ATOM   4686 C  CG  . TYR B 1 92  ? 32.222  -12.277 23.299  1   22.184 ? 84   TYR B CG  1 
ATOM   4687 C  CD1 . TYR B 1 92  ? 32.234  -12.831 24.584  1   24.129 ? 84   TYR B CD1 1 
ATOM   4688 C  CD2 . TYR B 1 92  ? 33.265  -12.564 22.402  1   25.363 ? 84   TYR B CD2 1 
ATOM   4689 C  CE1 . TYR B 1 92  ? 33.26   -13.687 24.963  1   25.095 ? 84   TYR B CE1 1 
ATOM   4690 C  CE2 . TYR B 1 92  ? 34.322  -13.365 22.812  1   25.453 ? 84   TYR B CE2 1 
ATOM   4691 C  CZ  . TYR B 1 92  ? 34.292  -13.939 24.074  1   24.532 ? 84   TYR B CZ  1 
ATOM   4692 O  OH  . TYR B 1 92  ? 35.348  -14.712 24.472  1   27.25  ? 84   TYR B OH  1 
ATOM   4693 N  N   . TYR B 1 93  ? 32.77   -8.803  22.064  1   24.402 ? 85   TYR B N   1 
ATOM   4694 C  CA  . TYR B 1 93  ? 34.061  -8.311  21.588  1   25.058 ? 85   TYR B CA  1 
ATOM   4695 C  C   . TYR B 1 93  ? 34.114  -6.784  21.642  1   27.503 ? 85   TYR B C   1 
ATOM   4696 O  O   . TYR B 1 93  ? 33.254  -6.138  21.047  1   28.005 ? 85   TYR B O   1 
ATOM   4697 C  CB  . TYR B 1 93  ? 34.265  -8.821  20.169  1   27.978 ? 85   TYR B CB  1 
ATOM   4698 C  CG  . TYR B 1 93  ? 35.626  -8.467  19.568  1   29.681 ? 85   TYR B CG  1 
ATOM   4699 C  CD1 . TYR B 1 93  ? 36.809  -9.057  20.043  1   31.329 ? 85   TYR B CD1 1 
ATOM   4700 C  CD2 . TYR B 1 93  ? 35.717  -7.558  18.515  1   25.999 ? 85   TYR B CD2 1 
ATOM   4701 C  CE1 . TYR B 1 93  ? 38.041  -8.758  19.463  1   28.436 ? 85   TYR B CE1 1 
ATOM   4702 C  CE2 . TYR B 1 93  ? 36.944  -7.282  17.921  1   26.378 ? 85   TYR B CE2 1 
ATOM   4703 C  CZ  . TYR B 1 93  ? 38.104  -7.886  18.393  1   29.667 ? 85   TYR B CZ  1 
ATOM   4704 O  OH  . TYR B 1 93  ? 39.31   -7.602  17.781  1   31.512 ? 85   TYR B OH  1 
ATOM   4705 N  N   . LYS B 1 94  ? 35.128  -6.237  22.34   1   27.102 ? 86   LYS B N   1 
ATOM   4706 C  CA  . LYS B 1 94  ? 35.34   -4.795  22.465  1   28.447 ? 86   LYS B CA  1 
ATOM   4707 C  C   . LYS B 1 94  ? 34.05   -4.079  22.892  1   28.148 ? 86   LYS B C   1 
ATOM   4708 O  O   . LYS B 1 94  ? 33.714  -3.033  22.343  1   28.252 ? 86   LYS B O   1 
ATOM   4709 C  CB  . LYS B 1 94  ? 35.959  -4.228  21.178  1   29.289 ? 86   LYS B CB  1 
ATOM   4710 C  CG  . LYS B 1 94  ? 37.324  -4.798  20.823  1   36.613 ? 86   LYS B CG  1 
ATOM   4711 C  CD  . LYS B 1 94  ? 37.802  -4.136  19.531  1   38.056 ? 86   LYS B CD  1 
ATOM   4712 C  CE  . LYS B 1 94  ? 39.237  -3.79   19.448  1   48.142 ? 86   LYS B CE  1 
ATOM   4713 N  NZ  . LYS B 1 94  ? 39.707  -2.959  20.568  1   41.246 ? 86   LYS B NZ  1 
ATOM   4714 N  N   . GLY B 1 95  ? 33.274  -4.704  23.797  1   26.664 ? 87   GLY B N   1 
ATOM   4715 C  CA  . GLY B 1 95  ? 32.048  -4.117  24.322  1   27.949 ? 87   GLY B CA  1 
ATOM   4716 C  C   . GLY B 1 95  ? 30.971  -3.922  23.245  1   26.98  ? 87   GLY B C   1 
ATOM   4717 O  O   . GLY B 1 95  ? 30.024  -3.193  23.475  1   28.845 ? 87   GLY B O   1 
ATOM   4718 N  N   . GLY B 1 96  ? 31.108  -4.593  22.087  1   26.504 ? 88   GLY B N   1 
ATOM   4719 C  CA  . GLY B 1 96  ? 30.206  -4.403  20.949  1   25.577 ? 88   GLY B CA  1 
ATOM   4720 C  C   . GLY B 1 96  ? 30.374  -3.058  20.246  1   26.448 ? 88   GLY B C   1 
ATOM   4721 O  O   . GLY B 1 96  ? 29.542  -2.7    19.402  1   28.537 ? 88   GLY B O   1 
ATOM   4722 N  N   . GLU B 1 97  ? 31.507  -2.354  20.511  1   27.59  ? 89   GLU B N   1 
ATOM   4723 C  CA  . GLU B 1 97  ? 31.79   -1.052  19.917  1   30.183 ? 89   GLU B CA  1 
ATOM   4724 C  C   . GLU B 1 97  ? 31.851  -1.098  18.39   1   29.626 ? 89   GLU B C   1 
ATOM   4725 O  O   . GLU B 1 97  ? 31.508  -0.104  17.757  1   27.231 ? 89   GLU B O   1 
ATOM   4726 C  CB  . GLU B 1 97  ? 33.088  -0.434  20.451  1   38.924 ? 89   GLU B CB  1 
ATOM   4727 C  CG  . GLU B 1 97  ? 32.951  0.097   21.876  1   54.841 ? 89   GLU B CG  1 
ATOM   4728 C  CD  . GLU B 1 97  ? 31.901  1.174   22.073  1   70.534 ? 89   GLU B CD  1 
ATOM   4729 O  OE1 . GLU B 1 97  ? 32.176  2.314   21.637  1   75.604 ? 89   GLU B OE1 1 
ATOM   4730 O  OE2 . GLU B 1 97  ? 30.808  0.861   22.616  1   73.55  ? 89   GLU B OE2 1 
ATOM   4731 N  N   . LEU B 1 98  ? 32.236  -2.246  17.796  1   23.82  ? 90   LEU B N   1 
ATOM   4732 C  CA  . LEU B 1 98  ? 32.414  -2.331  16.347  1   23.732 ? 90   LEU B CA  1 
ATOM   4733 C  C   . LEU B 1 98  ? 31.328  -3.184  15.681  1   26.627 ? 90   LEU B C   1 
ATOM   4734 O  O   . LEU B 1 98  ? 31.523  -3.688  14.567  1   25.019 ? 90   LEU B O   1 
ATOM   4735 C  CB  . LEU B 1 98  ? 33.823  -2.852  16.065  1   28.046 ? 90   LEU B CB  1 
ATOM   4736 C  CG  . LEU B 1 98  ? 34.988  -1.952  16.504  1   30.779 ? 90   LEU B CG  1 
ATOM   4737 C  CD1 . LEU B 1 98  ? 36.315  -2.619  16.146  1   35.483 ? 90   LEU B CD1 1 
ATOM   4738 C  CD2 . LEU B 1 98  ? 34.912  -0.62   15.818  1   30.306 ? 90   LEU B CD2 1 
ATOM   4739 N  N   . ASN B 1 99  ? 30.195  -3.395  16.378  1   25.454 ? 91   ASN B N   1 
ATOM   4740 C  CA  . ASN B 1 99  ? 29.104  -4.141  15.759  1   27.552 ? 91   ASN B CA  1 
ATOM   4741 C  C   . ASN B 1 99  ? 28.659  -3.361  14.524  1   25.482 ? 91   ASN B C   1 
ATOM   4742 O  O   . ASN B 1 99  ? 28.66   -2.116  14.526  1   26.914 ? 91   ASN B O   1 
ATOM   4743 C  CB  . ASN B 1 99  ? 27.976  -4.443  16.75   1   25.76  ? 91   ASN B CB  1 
ATOM   4744 C  CG  . ASN B 1 99  ? 27.01   -3.287  16.899  1   32.412 ? 91   ASN B CG  1 
ATOM   4745 O  OD1 . ASN B 1 99  ? 26.138  -3.077  16.041  1   29.695 ? 91   ASN B OD1 1 
ATOM   4746 N  ND2 . ASN B 1 99  ? 27.16   -2.521  17.975  1   29.914 ? 91   ASN B ND2 1 
ATOM   4747 N  N   . ALA B 1 100 ? 28.31   -4.093  13.459  1   24.844 ? 92   ALA B N   1 
ATOM   4748 C  CA  . ALA B 1 100 ? 27.945  -3.461  12.204  1   24     ? 92   ALA B CA  1 
ATOM   4749 C  C   . ALA B 1 100 ? 26.418  -3.461  12.064  1   22.423 ? 92   ALA B C   1 
ATOM   4750 O  O   . ALA B 1 100 ? 25.753  -4.322  12.649  1   22.871 ? 92   ALA B O   1 
ATOM   4751 C  CB  . ALA B 1 100 ? 28.602  -4.184  11.042  1   22.972 ? 92   ALA B CB  1 
ATOM   4752 N  N   . PRO B 1 101 ? 25.792  -2.532  11.294  1   22.942 ? 93   PRO B N   1 
ATOM   4753 C  CA  . PRO B 1 101 ? 24.336  -2.546  11.116  1   24.602 ? 93   PRO B CA  1 
ATOM   4754 C  C   . PRO B 1 101 ? 23.792  -3.821  10.471  1   24.164 ? 93   PRO B C   1 
ATOM   4755 O  O   . PRO B 1 101 ? 22.61   -4.129  10.643  1   23.806 ? 93   PRO B O   1 
ATOM   4756 C  CB  . PRO B 1 101 ? 24.011  -1.316  10.243  1   26.083 ? 93   PRO B CB  1 
ATOM   4757 C  CG  . PRO B 1 101 ? 25.368  -1.037  9.585   1   26.919 ? 93   PRO B CG  1 
ATOM   4758 C  CD  . PRO B 1 101 ? 26.409  -1.374  10.619  1   24.275 ? 93   PRO B CD  1 
ATOM   4759 N  N   . ILE B 1 102 ? 24.676  -4.564  9.789   1   21.248 ? 94   ILE B N   1 
ATOM   4760 C  CA  . ILE B 1 102 ? 24.295  -5.798  9.115   1   20.432 ? 94   ILE B CA  1 
ATOM   4761 C  C   . ILE B 1 102 ? 24.51   -7.034  9.999   1   19.902 ? 94   ILE B C   1 
ATOM   4762 O  O   . ILE B 1 102 ? 24.356  -8.151  9.511   1   19.281 ? 94   ILE B O   1 
ATOM   4763 C  CB  . ILE B 1 102 ? 25.002  -5.919  7.739   1   21.405 ? 94   ILE B CB  1 
ATOM   4764 C  CG1 . ILE B 1 102 ? 26.569  -5.982  7.902   1   21.96  ? 94   ILE B CG1 1 
ATOM   4765 C  CG2 . ILE B 1 102 ? 24.518  -4.838  6.752   1   21.808 ? 94   ILE B CG2 1 
ATOM   4766 C  CD1 . ILE B 1 102 ? 27.302  -6.341  6.6     1   21.163 ? 94   ILE B CD1 1 
ATOM   4767 N  N   . ASP B 1 103 ? 24.865  -6.85   11.286  1   22.296 ? 95   ASP B N   1 
ATOM   4768 C  CA  . ASP B 1 103 ? 25.232  -7.969  12.133  1   23.187 ? 95   ASP B CA  1 
ATOM   4769 C  C   . ASP B 1 103 ? 24.06   -8.622  12.875  1   21.501 ? 95   ASP B C   1 
ATOM   4770 O  O   . ASP B 1 103 ? 24.117  -9.823  13.092  1   24.871 ? 95   ASP B O   1 
ATOM   4771 C  CB  . ASP B 1 103 ? 26.154  -7.535  13.258  1   22.933 ? 95   ASP B CB  1 
ATOM   4772 C  CG  . ASP B 1 103 ? 27.638  -7.759  13.032  1   25.547 ? 95   ASP B CG  1 
ATOM   4773 O  OD1 . ASP B 1 103 ? 27.991  -8.886  12.623  1   25.1   ? 95   ASP B OD1 1 
ATOM   4774 O  OD2 . ASP B 1 103 ? 28.421  -6.821  13.316  1   28.044 ? 95   ASP B OD2 1 
ATOM   4775 N  N   . GLY B 1 104 ? 23.038  -7.881  13.296  1   22.742 ? 96   GLY B N   1 
ATOM   4776 C  CA  . GLY B 1 104 ? 22.154  -8.362  14.379  1   20.818 ? 96   GLY B CA  1 
ATOM   4777 C  C   . GLY B 1 104 ? 21.341  -9.615  14.008  1   19.433 ? 96   GLY B C   1 
ATOM   4778 O  O   . GLY B 1 104 ? 20.994  -9.809  12.835  1   19.54  ? 96   GLY B O   1 
ATOM   4779 N  N   . ASP B 1 105 ? 20.954  -10.38  15.037  1   17.965 ? 97   ASP B N   1 
ATOM   4780 C  CA  . ASP B 1 105 ? 20.115  -11.579 14.884  1   18.174 ? 97   ASP B CA  1 
ATOM   4781 C  C   . ASP B 1 105 ? 18.907  -11.311 14      1   18.104 ? 97   ASP B C   1 
ATOM   4782 O  O   . ASP B 1 105 ? 18.21   -10.307 14.19   1   18.596 ? 97   ASP B O   1 
ATOM   4783 C  CB  . ASP B 1 105 ? 19.591  -12.036 16.247  1   17.476 ? 97   ASP B CB  1 
ATOM   4784 C  CG  . ASP B 1 105 ? 20.744  -12.423 17.169  1   21.305 ? 97   ASP B CG  1 
ATOM   4785 O  OD1 . ASP B 1 105 ? 21.474  -13.406 16.835  1   22.661 ? 97   ASP B OD1 1 
ATOM   4786 O  OD2 . ASP B 1 105 ? 20.963  -11.698 18.16   1   20.877 ? 97   ASP B OD2 1 
ATOM   4787 N  N   . GLY B 1 106 ? 18.717  -12.208 13.002  1   17.786 ? 98   GLY B N   1 
ATOM   4788 C  CA  . GLY B 1 106 ? 17.594  -12.076 12.063  1   17.335 ? 98   GLY B CA  1 
ATOM   4789 C  C   . GLY B 1 106 ? 16.252  -12.281 12.769  1   16.401 ? 98   GLY B C   1 
ATOM   4790 O  O   . GLY B 1 106 ? 16.047  -13.273 13.482  1   19.445 ? 98   GLY B O   1 
ATOM   4791 N  N   . THR B 1 107 ? 15.313  -11.364 12.47   1   18.208 ? 99   THR B N   1 
ATOM   4792 C  CA  . THR B 1 107 ? 13.947  -11.536 12.945  1   18.883 ? 99   THR B CA  1 
ATOM   4793 C  C   . THR B 1 107 ? 13.059  -11.284 11.732  1   19.023 ? 99   THR B C   1 
ATOM   4794 O  O   . THR B 1 107 ? 13.299  -10.344 10.98   1   19.586 ? 99   THR B O   1 
ATOM   4795 C  CB  . THR B 1 107 ? 13.673  -10.595 14.128  1   21.935 ? 99   THR B CB  1 
ATOM   4796 O  OG1 . THR B 1 107 ? 12.305  -10.777 14.472  1   23.579 ? 99   THR B OG1 1 
ATOM   4797 C  CG2 . THR B 1 107 ? 13.941  -9.111  13.856  1   20.118 ? 99   THR B CG2 1 
ATOM   4798 N  N   . VAL B 1 108 ? 12.032  -12.125 11.58   1   18.251 ? 100  VAL B N   1 
ATOM   4799 C  CA  . VAL B 1 108 ? 11.146  -11.996 10.427  1   18.03  ? 100  VAL B CA  1 
ATOM   4800 C  C   . VAL B 1 108 ? 9.829   -11.422 10.907  1   17.208 ? 100  VAL B C   1 
ATOM   4801 O  O   . VAL B 1 108 ? 9.26    -11.935 11.873  1   18.157 ? 100  VAL B O   1 
ATOM   4802 C  CB  . VAL B 1 108 ? 10.947  -13.4   9.824   1   18.9   ? 100  VAL B CB  1 
ATOM   4803 C  CG1 . VAL B 1 108 ? 9.859   -13.427 8.732   1   16.341 ? 100  VAL B CG1 1 
ATOM   4804 C  CG2 . VAL B 1 108 ? 12.263  -13.929 9.257   1   18.516 ? 100  VAL B CG2 1 
ATOM   4805 N  N   . ALA B 1 109 ? 9.335   -10.404 10.172  1   18.306 ? 101  ALA B N   1 
ATOM   4806 C  CA  . ALA B 1 109 ? 7.968   -9.919  10.354  1   18.31  ? 101  ALA B CA  1 
ATOM   4807 C  C   . ALA B 1 109 ? 7.162   -10.421 9.164   1   19.997 ? 101  ALA B C   1 
ATOM   4808 O  O   . ALA B 1 109 ? 7.586   -10.329 8.017   1   23.67  ? 101  ALA B O   1 
ATOM   4809 C  CB  . ALA B 1 109 ? 7.938   -8.385  10.412  1   21.113 ? 101  ALA B CB  1 
ATOM   4810 N  N   . ALA B 1 110 ? 5.986   -10.965 9.437   1   18.621 ? 102  ALA B N   1 
ATOM   4811 C  CA  . ALA B 1 110 ? 5.096   -11.416 8.379   1   18.691 ? 102  ALA B CA  1 
ATOM   4812 C  C   . ALA B 1 110 ? 3.8     -10.622 8.485   1   20.418 ? 102  ALA B C   1 
ATOM   4813 O  O   . ALA B 1 110 ? 3.28    -10.443 9.599   1   19.998 ? 102  ALA B O   1 
ATOM   4814 C  CB  . ALA B 1 110 ? 4.808   -12.872 8.56    1   19.06  ? 102  ALA B CB  1 
ATOM   4815 N  N   . PHE B 1 111 ? 3.357   -10.093 7.337   1   19.369 ? 103  PHE B N   1 
ATOM   4816 C  CA  . PHE B 1 111 ? 2.091   -9.392  7.231   1   19.573 ? 103  PHE B CA  1 
ATOM   4817 C  C   . PHE B 1 111 ? 1.251   -10.141 6.206   1   18.709 ? 103  PHE B C   1 
ATOM   4818 O  O   . PHE B 1 111 ? 1.545   -10.092 4.992   1   18.876 ? 103  PHE B O   1 
ATOM   4819 C  CB  . PHE B 1 111 ? 2.263   -7.931  6.796   1   20.885 ? 103  PHE B CB  1 
ATOM   4820 C  CG  . PHE B 1 111 ? 3.114   -7.098  7.75    1   21.309 ? 103  PHE B CG  1 
ATOM   4821 C  CD1 . PHE B 1 111 ? 4.495   -7.019  7.577   1   22.618 ? 103  PHE B CD1 1 
ATOM   4822 C  CD2 . PHE B 1 111 ? 2.51    -6.365  8.776   1   23.894 ? 103  PHE B CD2 1 
ATOM   4823 C  CE1 . PHE B 1 111 ? 5.276   -6.232  8.413   1   22.577 ? 103  PHE B CE1 1 
ATOM   4824 C  CE2 . PHE B 1 111 ? 3.294   -5.549  9.622   1   23.51  ? 103  PHE B CE2 1 
ATOM   4825 C  CZ  . PHE B 1 111 ? 4.675   -5.503  9.431   1   22.283 ? 103  PHE B CZ  1 
ATOM   4826 N  N   . ARG B 1 112 ? 0.244   -10.855 6.729   1   20.328 ? 104  ARG B N   1 
ATOM   4827 C  CA  . ARG B 1 112 ? -0.514  -11.759 5.88    1   22.372 ? 104  ARG B CA  1 
ATOM   4828 C  C   . ARG B 1 112 ? -1.832  -11.093 5.5     1   20.062 ? 104  ARG B C   1 
ATOM   4829 O  O   . ARG B 1 112 ? -2.537  -10.627 6.381   1   20.641 ? 104  ARG B O   1 
ATOM   4830 C  CB  . ARG B 1 112 ? -0.676  -13.142 6.496   1   21.142 ? 104  ARG B CB  1 
ATOM   4831 C  CG  . ARG B 1 112 ? -1.485  -14.033 5.561   1   22.197 ? 104  ARG B CG  1 
ATOM   4832 C  CD  . ARG B 1 112 ? -1.333  -15.464 5.942   1   20.959 ? 104  ARG B CD  1 
ATOM   4833 N  NE  . ARG B 1 112 ? 0.048   -15.908 5.704   1   20     ? 104  ARG B NE  1 
ATOM   4834 C  CZ  . ARG B 1 112 ? 0.49    -17.132 6.085   1   21.31  ? 104  ARG B CZ  1 
ATOM   4835 N  NH1 . ARG B 1 112 ? -0.327  -17.957 6.724   1   24.166 ? 104  ARG B NH1 1 
ATOM   4836 N  NH2 . ARG B 1 112 ? 1.735   -17.494 5.827   1   23.216 ? 104  ARG B NH2 1 
ATOM   4837 N  N   . PHE B 1 113 ? -2.079  -11.037 4.184   1   18.738 ? 105  PHE B N   1 
ATOM   4838 C  CA  . PHE B 1 113 ? -3.243  -10.367 3.6     1   23.359 ? 105  PHE B CA  1 
ATOM   4839 C  C   . PHE B 1 113 ? -4.159  -11.44  3.015   1   22.88  ? 105  PHE B C   1 
ATOM   4840 O  O   . PHE B 1 113 ? -3.765  -12.164 2.119   1   23.691 ? 105  PHE B O   1 
ATOM   4841 C  CB  . PHE B 1 113 ? -2.817  -9.43   2.464   1   21.469 ? 105  PHE B CB  1 
ATOM   4842 C  CG  . PHE B 1 113 ? -1.991  -8.22   2.884   1   21.752 ? 105  PHE B CG  1 
ATOM   4843 C  CD1 . PHE B 1 113 ? -0.642  -8.376  3.244   1   21.054 ? 105  PHE B CD1 1 
ATOM   4844 C  CD2 . PHE B 1 113 ? -2.559  -6.935  2.934   1   23.913 ? 105  PHE B CD2 1 
ATOM   4845 C  CE1 . PHE B 1 113 ? 0.11    -7.27   3.661   1   23.106 ? 105  PHE B CE1 1 
ATOM   4846 C  CE2 . PHE B 1 113 ? -1.8    -5.825  3.335   1   26.424 ? 105  PHE B CE2 1 
ATOM   4847 C  CZ  . PHE B 1 113 ? -0.471  -5.994  3.717   1   24.464 ? 105  PHE B CZ  1 
ATOM   4848 N  N   . LYS B 1 114 ? -5.385  -11.524 3.544   1   25.162 ? 106  LYS B N   1 
ATOM   4849 C  CA  . LYS B 1 114 ? -6.378  -12.464 3.037   1   27.876 ? 106  LYS B CA  1 
ATOM   4850 C  C   . LYS B 1 114 ? -7.756  -11.847 3.234   1   30.549 ? 106  LYS B C   1 
ATOM   4851 O  O   . LYS B 1 114 ? -8.117  -11.479 4.348   1   27.534 ? 106  LYS B O   1 
ATOM   4852 C  CB  . LYS B 1 114 ? -6.166  -13.823 3.701   1   31.217 ? 106  LYS B CB  1 
ATOM   4853 C  CG  . LYS B 1 114 ? -7.048  -14.917 3.09    1   38.932 ? 106  LYS B CG  1 
ATOM   4854 C  CD  . LYS B 1 114 ? -6.745  -16.302 3.64    1   37.127 ? 106  LYS B CD  1 
ATOM   4855 C  CE  . LYS B 1 114 ? -7.61   -17.225 2.853   1   40.7   ? 106  LYS B CE  1 
ATOM   4856 N  NZ  . LYS B 1 114 ? -8.133  -18.272 3.718   1   43.839 ? 106  LYS B NZ  1 
ATOM   4857 N  N   . ASP B 1 115 ? -8.459  -11.635 2.116   1   32.509 ? 107  ASP B N   1 
ATOM   4858 C  CA  . ASP B 1 115 ? -9.818  -11.126 2.106   1   31.118 ? 107  ASP B CA  1 
ATOM   4859 C  C   . ASP B 1 115 ? -9.903  -9.769  2.8     1   35.135 ? 107  ASP B C   1 
ATOM   4860 O  O   . ASP B 1 115 ? -10.871 -9.486  3.499   1   32.374 ? 107  ASP B O   1 
ATOM   4861 C  CB  . ASP B 1 115 ? -10.801 -12.13  2.683   1   35.595 ? 107  ASP B CB  1 
ATOM   4862 C  CG  . ASP B 1 115 ? -10.812 -13.496 2.021   1   46.632 ? 107  ASP B CG  1 
ATOM   4863 O  OD1 . ASP B 1 115 ? -10.817 -13.532 0.776   1   47.318 ? 107  ASP B OD1 1 
ATOM   4864 O  OD2 . ASP B 1 115 ? -10.849 -14.515 2.755   1   51.16  ? 107  ASP B OD2 1 
ATOM   4865 N  N   . GLY B 1 116 ? -8.916  -8.907  2.549   1   28.241 ? 108  GLY B N   1 
ATOM   4866 C  CA  . GLY B 1 116 ? -8.93   -7.57   3.091   1   28.92  ? 108  GLY B CA  1 
ATOM   4867 C  C   . GLY B 1 116 ? -8.481  -7.51   4.556   1   28.094 ? 108  GLY B C   1 
ATOM   4868 O  O   . GLY B 1 116 ? -8.344  -6.404  5.056   1   28.07  ? 108  GLY B O   1 
ATOM   4869 N  N   . LYS B 1 117 ? -8.192  -8.644  5.211   1   27.489 ? 109  LYS B N   1 
ATOM   4870 C  CA  . LYS B 1 117 ? -7.691  -8.566  6.582   1   23.838 ? 109  LYS B CA  1 
ATOM   4871 C  C   . LYS B 1 117 ? -6.186  -8.819  6.653   1   23.497 ? 109  LYS B C   1 
ATOM   4872 O  O   . LYS B 1 117 ? -5.653  -9.597  5.874   1   22.471 ? 109  LYS B O   1 
ATOM   4873 C  CB  . LYS B 1 117 ? -8.436  -9.6    7.426   1   30.992 ? 109  LYS B CB  1 
ATOM   4874 C  CG  . LYS B 1 117 ? -9.887  -9.119  7.566   1   42.31  ? 109  LYS B CG  1 
ATOM   4875 C  CD  . LYS B 1 117 ? -10.146 -7.705  8.137   1   40.884 ? 109  LYS B CD  1 
ATOM   4876 C  CE  . LYS B 1 117 ? -11.425 -7.792  8.785   1   43.666 ? 109  LYS B CE  1 
ATOM   4877 N  NZ  . LYS B 1 117 ? -12.216 -8.348  7.688   1   37.251 ? 109  LYS B NZ  1 
ATOM   4878 N  N   . VAL B 1 118 ? -5.537  -8.234  7.673   1   20.52  ? 110  VAL B N   1 
ATOM   4879 C  CA  . VAL B 1 118 ? -4.087  -8.309  7.773   1   21.771 ? 110  VAL B CA  1 
ATOM   4880 C  C   . VAL B 1 118 ? -3.739  -8.821  9.164   1   19.483 ? 110  VAL B C   1 
ATOM   4881 O  O   . VAL B 1 118 ? -4.21   -8.223  10.144  1   20.292 ? 110  VAL B O   1 
ATOM   4882 C  CB  . VAL B 1 118 ? -3.403  -6.941  7.526   1   23.099 ? 110  VAL B CB  1 
ATOM   4883 C  CG1 . VAL B 1 118 ? -1.89   -7.154  7.482   1   23.543 ? 110  VAL B CG1 1 
ATOM   4884 C  CG2 . VAL B 1 118 ? -3.858  -6.282  6.228   1   24.46  ? 110  VAL B CG2 1 
ATOM   4885 N  N   . ASP B 1 119 ? -2.928  -9.897  9.231   1   19.685 ? 111  ASP B N   1 
ATOM   4886 C  CA  . ASP B 1 119 ? -2.344  -10.31  10.496  1   20.03  ? 111  ASP B CA  1 
ATOM   4887 C  C   . ASP B 1 119 ? -0.843  -10.091 10.429  1   19.089 ? 111  ASP B C   1 
ATOM   4888 O  O   . ASP B 1 119 ? -0.231  -10.046 9.354   1   18.745 ? 111  ASP B O   1 
ATOM   4889 C  CB  . ASP B 1 119 ? -2.644  -11.758 10.868  1   20.254 ? 111  ASP B CB  1 
ATOM   4890 C  CG  . ASP B 1 119 ? -4.126  -12.138 10.942  1   22.021 ? 111  ASP B CG  1 
ATOM   4891 O  OD1 . ASP B 1 119 ? -4.95   -11.291 11.314  1   21.583 ? 111  ASP B OD1 1 
ATOM   4892 O  OD2 . ASP B 1 119 ? -4.433  -13.308 10.65   1   26.185 ? 111  ASP B OD2 1 
ATOM   4893 N  N   . TYR B 1 120 ? -0.273  -10.025 11.625  1   18.88  ? 112  TYR B N   1 
ATOM   4894 C  CA  . TYR B 1 120 ? 1.162   -9.826  11.762  1   18.896 ? 112  TYR B CA  1 
ATOM   4895 C  C   . TYR B 1 120 ? 1.718   -10.832 12.756  1   19.588 ? 112  TYR B C   1 
ATOM   4896 O  O   . TYR B 1 120 ? 1.096   -11.11  13.793  1   21.617 ? 112  TYR B O   1 
ATOM   4897 C  CB  . TYR B 1 120 ? 1.37    -8.421  12.328  1   19.748 ? 112  TYR B CB  1 
ATOM   4898 C  CG  . TYR B 1 120 ? 2.682   -8.1    13.007  1   21.732 ? 112  TYR B CG  1 
ATOM   4899 C  CD1 . TYR B 1 120 ? 3.822   -7.808  12.27   1   21.235 ? 112  TYR B CD1 1 
ATOM   4900 C  CD2 . TYR B 1 120 ? 2.743   -8.111  14.415  1   25.166 ? 112  TYR B CD2 1 
ATOM   4901 C  CE1 . TYR B 1 120 ? 5.013   -7.492  12.919  1   22.708 ? 112  TYR B CE1 1 
ATOM   4902 C  CE2 . TYR B 1 120 ? 3.938   -7.792  15.064  1   27.56  ? 112  TYR B CE2 1 
ATOM   4903 C  CZ  . TYR B 1 120 ? 5.054   -7.486  14.303  1   25.283 ? 112  TYR B CZ  1 
ATOM   4904 O  OH  . TYR B 1 120 ? 6.248   -7.106  14.801  1   29.8   ? 112  TYR B OH  1 
ATOM   4905 N  N   . ARG B 1 121 ? 2.937   -11.306 12.42   1   18.998 ? 113  ARG B N   1 
ATOM   4906 C  CA  . ARG B 1 121 ? 3.713   -12.11  13.344  1   18.838 ? 113  ARG B CA  1 
ATOM   4907 C  C   . ARG B 1 121 ? 5.166   -11.674 13.177  1   18.835 ? 113  ARG B C   1 
ATOM   4908 O  O   . ARG B 1 121 ? 5.631   -11.5   12.052  1   20.416 ? 113  ARG B O   1 
ATOM   4909 C  CB  . ARG B 1 121 ? 3.577   -13.621 13.075  1   19.615 ? 113  ARG B CB  1 
ATOM   4910 C  CG  . ARG B 1 121 ? 4.453   -14.442 14.026  1   17.208 ? 113  ARG B CG  1 
ATOM   4911 C  CD  . ARG B 1 121 ? 4.299   -15.971 13.722  1   18.135 ? 113  ARG B CD  1 
ATOM   4912 N  NE  . ARG B 1 121 ? 3.022   -16.502 14.228  1   21.556 ? 113  ARG B NE  1 
ATOM   4913 C  CZ  . ARG B 1 121 ? 2.822   -16.961 15.471  1   21.137 ? 113  ARG B CZ  1 
ATOM   4914 N  NH1 . ARG B 1 121 ? 3.743   -16.799 16.419  1   21.23  ? 113  ARG B NH1 1 
ATOM   4915 N  NH2 . ARG B 1 121 ? 1.691   -17.588 15.756  1   21.909 ? 113  ARG B NH2 1 
ATOM   4916 N  N   . GLN B 1 122 ? 5.871   -11.628 14.306  1   17.543 ? 114  GLN B N   1 
ATOM   4917 C  CA  . GLN B 1 122 ? 7.317   -11.443 14.256  1   19.687 ? 114  GLN B CA  1 
ATOM   4918 C  C   . GLN B 1 122 ? 7.997   -12.506 15.125  1   17.977 ? 114  GLN B C   1 
ATOM   4919 O  O   . GLN B 1 122 ? 7.506   -12.827 16.216  1   18.022 ? 114  GLN B O   1 
ATOM   4920 C  CB  . GLN B 1 122 ? 7.636   -10.051 14.79   1   22.865 ? 114  GLN B CB  1 
ATOM   4921 C  CG  . GLN B 1 122 ? 9.138   -9.791  14.667  1   25.304 ? 114  GLN B CG  1 
ATOM   4922 C  CD  . GLN B 1 122 ? 9.496   -8.383  14.285  1   34.915 ? 114  GLN B CD  1 
ATOM   4923 O  OE1 . GLN B 1 122 ? 8.626   -7.529  14.117  1   33.188 ? 114  GLN B OE1 1 
ATOM   4924 N  NE2 . GLN B 1 122 ? 10.791  -8.098  14.235  1   35.331 ? 114  GLN B NE2 1 
ATOM   4925 N  N   . ARG B 1 123 ? 9.098   -13.064 14.625  1   18.023 ? 115  ARG B N   1 
ATOM   4926 C  CA  . ARG B 1 123 ? 9.854   -14.02  15.417  1   19.145 ? 115  ARG B CA  1 
ATOM   4927 C  C   . ARG B 1 123 ? 11.318  -14.02  14.969  1   19.143 ? 115  ARG B C   1 
ATOM   4928 O  O   . ARG B 1 123 ? 11.616  -13.97  13.767  1   17.828 ? 115  ARG B O   1 
ATOM   4929 C  CB  . ARG B 1 123 ? 9.247   -15.407 15.142  1   17.482 ? 115  ARG B CB  1 
ATOM   4930 C  CG  . ARG B 1 123 ? 9.604   -16.433 16.221  1   17.288 ? 115  ARG B CG  1 
ATOM   4931 C  CD  . ARG B 1 123 ? 8.669   -17.638 16.008  1   20.266 ? 115  ARG B CD  1 
ATOM   4932 N  NE  . ARG B 1 123 ? 8.906   -18.571 17.112  1   22.623 ? 115  ARG B NE  1 
ATOM   4933 C  CZ  . ARG B 1 123 ? 8.179   -19.68  17.343  1   27.983 ? 115  ARG B CZ  1 
ATOM   4934 N  NH1 . ARG B 1 123 ? 7.15    -19.991 16.569  1   28.432 ? 115  ARG B NH1 1 
ATOM   4935 N  NH2 . ARG B 1 123 ? 8.45    -20.431 18.402  1   28.143 ? 115  ARG B NH2 1 
ATOM   4936 N  N   . PHE B 1 124 ? 12.173  -14.299 15.952  1   18.819 ? 116  PHE B N   1 
ATOM   4937 C  CA  . PHE B 1 124 ? 13.585  -14.49  15.635  1   19.034 ? 116  PHE B CA  1 
ATOM   4938 C  C   . PHE B 1 124 ? 13.804  -15.831 14.943  1   20.842 ? 116  PHE B C   1 
ATOM   4939 O  O   . PHE B 1 124 ? 13.189  -16.836 15.29   1   19.709 ? 116  PHE B O   1 
ATOM   4940 C  CB  . PHE B 1 124 ? 14.431  -14.564 16.902  1   17.974 ? 116  PHE B CB  1 
ATOM   4941 C  CG  . PHE B 1 124 ? 14.732  -13.165 17.414  1   18.569 ? 116  PHE B CG  1 
ATOM   4942 C  CD1 . PHE B 1 124 ? 15.612  -12.325 16.713  1   20.179 ? 116  PHE B CD1 1 
ATOM   4943 C  CD2 . PHE B 1 124 ? 14.194  -12.736 18.646  1   18.974 ? 116  PHE B CD2 1 
ATOM   4944 C  CE1 . PHE B 1 124 ? 15.907  -11.055 17.195  1   20.35  ? 116  PHE B CE1 1 
ATOM   4945 C  CE2 . PHE B 1 124 ? 14.45   -11.432 19.118  1   20.409 ? 116  PHE B CE2 1 
ATOM   4946 C  CZ  . PHE B 1 124 ? 15.358  -10.62  18.423  1   20.144 ? 116  PHE B CZ  1 
ATOM   4947 N  N   . VAL B 1 125 ? 14.723  -15.801 13.977  1   19.294 ? 117  VAL B N   1 
ATOM   4948 C  CA  . VAL B 1 125 ? 15.305  -17.015 13.429  1   19.173 ? 117  VAL B CA  1 
ATOM   4949 C  C   . VAL B 1 125 ? 16.092  -17.69  14.541  1   18.267 ? 117  VAL B C   1 
ATOM   4950 O  O   . VAL B 1 125 ? 17.009  -17.08  15.11   1   18.868 ? 117  VAL B O   1 
ATOM   4951 C  CB  . VAL B 1 125 ? 16.17   -16.787 12.181  1   16.944 ? 117  VAL B CB  1 
ATOM   4952 C  CG1 . VAL B 1 125 ? 16.565  -18.141 11.556  1   18.625 ? 117  VAL B CG1 1 
ATOM   4953 C  CG2 . VAL B 1 125 ? 15.464  -15.948 11.115  1   17.019 ? 117  VAL B CG2 1 
ATOM   4954 N  N   . GLU B 1 126 ? 15.817  -18.987 14.779  1   17.606 ? 118  GLU B N   1 
ATOM   4955 C  CA  . GLU B 1 126 ? 16.563  -19.692 15.819  1   20.069 ? 118  GLU B CA  1 
ATOM   4956 C  C   . GLU B 1 126 ? 17.862  -20.255 15.237  1   20.375 ? 118  GLU B C   1 
ATOM   4957 O  O   . GLU B 1 126 ? 18.075  -21.477 15.177  1   19.917 ? 118  GLU B O   1 
ATOM   4958 C  CB  . GLU B 1 126 ? 15.782  -20.875 16.392  1   23.734 ? 118  GLU B CB  1 
ATOM   4959 C  CG  . GLU B 1 126 ? 14.697  -20.495 17.376  1   35.366 ? 118  GLU B CG  1 
ATOM   4960 C  CD  . GLU B 1 126 ? 14.244  -21.843 17.974  1   39.475 ? 118  GLU B CD  1 
ATOM   4961 O  OE1 . GLU B 1 126 ? 14.585  -23.009 17.593  1   36.028 ? 118  GLU B OE1 1 
ATOM   4962 O  OE2 . GLU B 1 126 ? 13.496  -21.674 18.912  1   33.387 ? 118  GLU B OE2 1 
ATOM   4963 N  N   . THR B 1 127 ? 18.751  -19.35  14.78   1   19.708 ? 119  THR B N   1 
ATOM   4964 C  CA  . THR B 1 127 ? 20.064  -19.754 14.282  1   18.118 ? 119  THR B CA  1 
ATOM   4965 C  C   . THR B 1 127 ? 20.827  -20.445 15.41   1   18.217 ? 119  THR B C   1 
ATOM   4966 O  O   . THR B 1 127 ? 20.541  -20.22  16.589  1   18.891 ? 119  THR B O   1 
ATOM   4967 C  CB  . THR B 1 127 ? 20.845  -18.545 13.744  1   18.468 ? 119  THR B CB  1 
ATOM   4968 O  OG1 . THR B 1 127 ? 21.184  -17.743 14.884  1   18.646 ? 119  THR B OG1 1 
ATOM   4969 C  CG2 . THR B 1 127 ? 20.056  -17.757 12.712  1   18.655 ? 119  THR B CG2 1 
ATOM   4970 N  N   . ASP B 1 128 ? 21.834  -21.256 15.034  1   18.637 ? 120  ASP B N   1 
ATOM   4971 C  CA  . ASP B 1 128 ? 22.7    -21.821 16.067  1   20.687 ? 120  ASP B CA  1 
ATOM   4972 C  C   . ASP B 1 128 ? 23.29   -20.76  16.996  1   19.024 ? 120  ASP B C   1 
ATOM   4973 O  O   . ASP B 1 128 ? 23.371  -20.953 18.225  1   18.546 ? 120  ASP B O   1 
ATOM   4974 C  CB  . ASP B 1 128 ? 23.777  -22.699 15.442  1   18.46  ? 120  ASP B CB  1 
ATOM   4975 C  CG  . ASP B 1 128 ? 23.24   -24.047 14.983  1   21.687 ? 120  ASP B CG  1 
ATOM   4976 O  OD1 . ASP B 1 128 ? 22.088  -24.37  15.366  1   21.2   ? 120  ASP B OD1 1 
ATOM   4977 O  OD2 . ASP B 1 128 ? 23.973  -24.756 14.259  1   21.627 ? 120  ASP B OD2 1 
ATOM   4978 N  N   . ARG B 1 129 ? 23.66   -19.622 16.393  1   19.011 ? 121  ARG B N   1 
ATOM   4979 C  CA  . ARG B 1 129 ? 24.181  -18.479 17.125  1   21.189 ? 121  ARG B CA  1 
ATOM   4980 C  C   . ARG B 1 129 ? 23.151  -17.9   18.099  1   17.696 ? 121  ARG B C   1 
ATOM   4981 O  O   . ARG B 1 129 ? 23.478  -17.626 19.254  1   17.872 ? 121  ARG B O   1 
ATOM   4982 C  CB  . ARG B 1 129 ? 24.641  -17.456 16.079  1   20.232 ? 121  ARG B CB  1 
ATOM   4983 C  CG  . ARG B 1 129 ? 24.845  -16.054 16.644  1   20.756 ? 121  ARG B CG  1 
ATOM   4984 C  CD  . ARG B 1 129 ? 25.712  -15.352 15.629  1   19.083 ? 121  ARG B CD  1 
ATOM   4985 N  NE  . ARG B 1 129 ? 25.938  -13.95  16.003  1   20.171 ? 121  ARG B NE  1 
ATOM   4986 C  CZ  . ARG B 1 129 ? 26.805  -13.172 15.366  1   20.562 ? 121  ARG B CZ  1 
ATOM   4987 N  NH1 . ARG B 1 129 ? 27.505  -13.641 14.345  1   20.07  ? 121  ARG B NH1 1 
ATOM   4988 N  NH2 . ARG B 1 129 ? 26.926  -11.88  15.714  1   19.711 ? 121  ARG B NH2 1 
ATOM   4989 N  N   . PHE B 1 130 ? 21.913  -17.703 17.615  1   18.244 ? 122  PHE B N   1 
ATOM   4990 C  CA  . PHE B 1 130 ? 20.871  -17.147 18.463  1   19.884 ? 122  PHE B CA  1 
ATOM   4991 C  C   . PHE B 1 130 ? 20.627  -18.061 19.653  1   20.172 ? 122  PHE B C   1 
ATOM   4992 O  O   . PHE B 1 130 ? 20.453  -17.575 20.782  1   20.71  ? 122  PHE B O   1 
ATOM   4993 C  CB  . PHE B 1 130 ? 19.619  -17.026 17.613  1   19.208 ? 122  PHE B CB  1 
ATOM   4994 C  CG  . PHE B 1 130 ? 18.379  -16.708 18.421  1   18.862 ? 122  PHE B CG  1 
ATOM   4995 C  CD1 . PHE B 1 130 ? 18.024  -15.372 18.696  1   18.775 ? 122  PHE B CD1 1 
ATOM   4996 C  CD2 . PHE B 1 130 ? 17.533  -17.751 18.858  1   18.724 ? 122  PHE B CD2 1 
ATOM   4997 C  CE1 . PHE B 1 130 ? 16.836  -15.107 19.403  1   20.523 ? 122  PHE B CE1 1 
ATOM   4998 C  CE2 . PHE B 1 130 ? 16.357  -17.467 19.57   1   19.681 ? 122  PHE B CE2 1 
ATOM   4999 C  CZ  . PHE B 1 130 ? 16.001  -16.15  19.82   1   20.411 ? 122  PHE B CZ  1 
ATOM   5000 N  N   . LYS B 1 131 ? 20.587  -19.38  19.368  1   19.622 ? 123  LYS B N   1 
ATOM   5001 C  CA  . LYS B 1 131 ? 20.306  -20.342 20.415  1   20.176 ? 123  LYS B CA  1 
ATOM   5002 C  C   . LYS B 1 131 ? 21.399  -20.332 21.487  1   20.04  ? 123  LYS B C   1 
ATOM   5003 O  O   . LYS B 1 131 ? 21.074  -20.35  22.69   1   19.649 ? 123  LYS B O   1 
ATOM   5004 C  CB  . LYS B 1 131 ? 20.163  -21.75  19.82   1   20.263 ? 123  LYS B CB  1 
ATOM   5005 C  CG  . LYS B 1 131 ? 18.916  -21.893 18.938  1   21.695 ? 123  LYS B CG  1 
ATOM   5006 C  CD  . LYS B 1 131 ? 18.532  -23.335 18.602  1   21.542 ? 123  LYS B CD  1 
ATOM   5007 C  CE  . LYS B 1 131 ? 19.595  -24.318 18.049  1   21.943 ? 123  LYS B CE  1 
ATOM   5008 N  NZ  . LYS B 1 131 ? 20.54   -24.768 19.1    1   22.833 ? 123  LYS B NZ  1 
ATOM   5009 N  N   . VAL B 1 132 ? 22.674  -20.286 21.065  1   20.115 ? 124  VAL B N   1 
ATOM   5010 C  CA  . VAL B 1 132 ? 23.784  -20.188 22.009  1   20.321 ? 124  VAL B CA  1 
ATOM   5011 C  C   . VAL B 1 132 ? 23.573  -18.98  22.908  1   19.752 ? 124  VAL B C   1 
ATOM   5012 O  O   . VAL B 1 132 ? 23.695  -19.071 24.13   1   19.074 ? 124  VAL B O   1 
ATOM   5013 C  CB  . VAL B 1 132 ? 25.166  -20.115 21.285  1   21.069 ? 124  VAL B CB  1 
ATOM   5014 C  CG1 . VAL B 1 132 ? 26.299  -19.522 22.136  1   23.171 ? 124  VAL B CG1 1 
ATOM   5015 C  CG2 . VAL B 1 132 ? 25.58   -21.481 20.754  1   23.312 ? 124  VAL B CG2 1 
ATOM   5016 N  N   . GLU B 1 133 ? 23.327  -17.832 22.282  1   19.407 ? 125  GLU B N   1 
ATOM   5017 C  CA  . GLU B 1 133 ? 23.341  -16.584 23.036  1   19.957 ? 125  GLU B CA  1 
ATOM   5018 C  C   . GLU B 1 133 ? 22.107  -16.468 23.944  1   20.241 ? 125  GLU B C   1 
ATOM   5019 O  O   . GLU B 1 133 ? 22.217  -15.94  25.051  1   19.903 ? 125  GLU B O   1 
ATOM   5020 C  CB  . GLU B 1 133 ? 23.457  -15.355 22.134  1   20.593 ? 125  GLU B CB  1 
ATOM   5021 C  CG  . GLU B 1 133 ? 24.847  -15.282 21.487  1   20.169 ? 125  GLU B CG  1 
ATOM   5022 C  CD  . GLU B 1 133 ? 25.127  -13.982 20.761  1   22.914 ? 125  GLU B CD  1 
ATOM   5023 O  OE1 . GLU B 1 133 ? 24.178  -13.237 20.409  1   24.73  ? 125  GLU B OE1 1 
ATOM   5024 O  OE2 . GLU B 1 133 ? 26.324  -13.641 20.6    1   20.258 ? 125  GLU B OE2 1 
ATOM   5025 N  N   . ARG B 1 134 ? 20.953  -16.99  23.501  1   20.184 ? 126  ARG B N   1 
ATOM   5026 C  CA  . ARG B 1 134 ? 19.766  -16.885 24.345  1   19.169 ? 126  ARG B CA  1 
ATOM   5027 C  C   . ARG B 1 134 ? 19.898  -17.837 25.542  1   20.498 ? 126  ARG B C   1 
ATOM   5028 O  O   . ARG B 1 134 ? 19.591  -17.443 26.688  1   21.177 ? 126  ARG B O   1 
ATOM   5029 C  CB  . ARG B 1 134 ? 18.513  -17.174 23.507  1   20.23  ? 126  ARG B CB  1 
ATOM   5030 C  CG  . ARG B 1 134 ? 17.267  -17.209 24.403  1   21.434 ? 126  ARG B CG  1 
ATOM   5031 C  CD  . ARG B 1 134 ? 15.94   -17.099 23.613  1   18.098 ? 126  ARG B CD  1 
ATOM   5032 N  NE  . ARG B 1 134 ? 15.811  -15.68  23.259  1   20.284 ? 126  ARG B NE  1 
ATOM   5033 C  CZ  . ARG B 1 134 ? 14.714  -15.151 22.702  1   20.99  ? 126  ARG B CZ  1 
ATOM   5034 N  NH1 . ARG B 1 134 ? 13.645  -15.924 22.483  1   19.123 ? 126  ARG B NH1 1 
ATOM   5035 N  NH2 . ARG B 1 134 ? 14.745  -13.873 22.323  1   19.188 ? 126  ARG B NH2 1 
ATOM   5036 N  N   . ARG B 1 135 ? 20.45   -19.044 25.303  1   20.685 ? 127  ARG B N   1 
ATOM   5037 C  CA  . ARG B 1 135 ? 20.604  -20.03  26.372  1   21.309 ? 127  ARG B CA  1 
ATOM   5038 C  C   . ARG B 1 135 ? 21.61   -19.521 27.403  1   26.011 ? 127  ARG B C   1 
ATOM   5039 O  O   . ARG B 1 135 ? 21.435  -19.743 28.612  1   24.454 ? 127  ARG B O   1 
ATOM   5040 C  CB  . ARG B 1 135 ? 21.01   -21.407 25.83   1   21.343 ? 127  ARG B CB  1 
ATOM   5041 C  CG  . ARG B 1 135 ? 19.836  -22.064 25.092  1   22.668 ? 127  ARG B CG  1 
ATOM   5042 C  CD  . ARG B 1 135 ? 20.268  -23.344 24.359  1   24.979 ? 127  ARG B CD  1 
ATOM   5043 N  NE  . ARG B 1 135 ? 20.724  -24.362 25.321  1   27.489 ? 127  ARG B NE  1 
ATOM   5044 C  CZ  . ARG B 1 135 ? 19.961  -25.033 26.178  1   29.622 ? 127  ARG B CZ  1 
ATOM   5045 N  NH1 . ARG B 1 135 ? 18.656  -25.127 26.019  1   27.502 ? 127  ARG B NH1 1 
ATOM   5046 N  NH2 . ARG B 1 135 ? 20.548  -25.685 27.163  1   32.957 ? 127  ARG B NH2 1 
ATOM   5047 N  N   . ALA B 1 136 ? 22.651  -18.831 26.908  1   22.417 ? 128  ALA B N   1 
ATOM   5048 C  CA  . ALA B 1 136 ? 23.69   -18.298 27.783  1   23.408 ? 128  ALA B CA  1 
ATOM   5049 C  C   . ALA B 1 136 ? 23.27   -16.963 28.387  1   23.153 ? 128  ALA B C   1 
ATOM   5050 O  O   . ALA B 1 136 ? 23.956  -16.503 29.303  1   26.283 ? 128  ALA B O   1 
ATOM   5051 C  CB  . ALA B 1 136 ? 25.031  -18.182 27.078  1   24.765 ? 128  ALA B CB  1 
ATOM   5052 N  N   . ARG B 1 137 ? 22.212  -16.333 27.844  1   20.697 ? 129  ARG B N   1 
ATOM   5053 C  CA  . ARG B 1 137 ? 21.821  -14.941 28.154  1   22.699 ? 129  ARG B CA  1 
ATOM   5054 C  C   . ARG B 1 137 ? 23.066  -14.037 27.99   1   24.263 ? 129  ARG B C   1 
ATOM   5055 O  O   . ARG B 1 137 ? 23.352  -13.183 28.83   1   22.311 ? 129  ARG B O   1 
ATOM   5056 C  CB  . ARG B 1 137 ? 21.246  -14.86  29.59   1   23.492 ? 129  ARG B CB  1 
ATOM   5057 C  CG  . ARG B 1 137 ? 20.517  -13.529 29.734  1   23.05  ? 129  ARG B CG  1 
ATOM   5058 C  CD  . ARG B 1 137 ? 20.755  -13.032 31.175  1   29.885 ? 129  ARG B CD  1 
ATOM   5059 N  NE  . ARG B 1 137 ? 20.277  -11.65  31.327  1   29.351 ? 129  ARG B NE  1 
ATOM   5060 C  CZ  . ARG B 1 137 ? 20.323  -10.91  32.434  1   33.562 ? 129  ARG B CZ  1 
ATOM   5061 N  NH1 . ARG B 1 137 ? 20.983  -11.356 33.47   1   32.588 ? 129  ARG B NH1 1 
ATOM   5062 N  NH2 . ARG B 1 137 ? 19.75   -9.715  32.512  1   31.588 ? 129  ARG B NH2 1 
ATOM   5063 N  N   . LYS B 1 138 ? 23.803  -14.188 26.88   1   20.078 ? 130  LYS B N   1 
ATOM   5064 C  CA  . LYS B 1 138 ? 25.109  -13.547 26.818  1   22.923 ? 130  LYS B CA  1 
ATOM   5065 C  C   . LYS B 1 138 ? 25.585  -13.557 25.372  1   20.506 ? 130  LYS B C   1 
ATOM   5066 O  O   . LYS B 1 138 ? 25.524  -14.593 24.72   1   22.072 ? 130  LYS B O   1 
ATOM   5067 C  CB  . LYS B 1 138 ? 26.14   -14.33  27.633  1   22.987 ? 130  LYS B CB  1 
ATOM   5068 C  CG  . LYS B 1 138 ? 27.502  -13.608 27.75   1   26.013 ? 130  LYS B CG  1 
ATOM   5069 C  CD  . LYS B 1 138 ? 28.498  -14.383 28.578  1   26.541 ? 130  LYS B CD  1 
ATOM   5070 C  CE  . LYS B 1 138 ? 29.858  -13.674 28.446  1   31.356 ? 130  LYS B CE  1 
ATOM   5071 N  NZ  . LYS B 1 138 ? 30.74   -14.201 29.474  1   35.764 ? 130  LYS B NZ  1 
ATOM   5072 N  N   . SER B 1 139 ? 26.076  -12.395 24.917  1   19.114 ? 131  SER B N   1 
ATOM   5073 C  CA  . SER B 1 139 ? 26.737  -12.295 23.615  1   20.152 ? 131  SER B CA  1 
ATOM   5074 C  C   . SER B 1 139 ? 28.007  -13.169 23.671  1   20.25  ? 131  SER B C   1 
ATOM   5075 O  O   . SER B 1 139 ? 28.762  -13.097 24.651  1   20.564 ? 131  SER B O   1 
ATOM   5076 C  CB  . SER B 1 139 ? 27.077  -10.832 23.343  1   20.125 ? 131  SER B CB  1 
ATOM   5077 O  OG  . SER B 1 139 ? 27.989  -10.701 22.256  1   21.524 ? 131  SER B OG  1 
ATOM   5078 N  N   . MET B 1 140 ? 28.207  -14.002 22.639  1   19.412 ? 132  MET B N   1 
ATOM   5079 C  CA  . MET B 1 140 ? 29.348  -14.922 22.553  1   20.604 ? 132  MET B CA  1 
ATOM   5080 C  C   . MET B 1 140 ? 30.023  -14.774 21.186  1   21.741 ? 132  MET B C   1 
ATOM   5081 O  O   . MET B 1 140 ? 30.916  -15.559 20.86   1   20.271 ? 132  MET B O   1 
ATOM   5082 C  CB  . MET B 1 140 ? 28.86   -16.38  22.73   1   21.43  ? 132  MET B CB  1 
ATOM   5083 C  CG  . MET B 1 140 ? 28.164  -16.678 24.061  1   27.898 ? 132  MET B CG  1 
ATOM   5084 S  SD  . MET B 1 140 ? 29.451  -16.853 25.293  1   33.78  ? 132  MET B SD  1 
ATOM   5085 C  CE  . MET B 1 140 ? 29.885  -18.606 25.212  1   33.047 ? 132  MET B CE  1 
ATOM   5086 N  N   . TYR B 1 141 ? 29.569  -13.786 20.388  1   18.263 ? 133  TYR B N   1 
ATOM   5087 C  CA  . TYR B 1 141 ? 30.091  -13.617 19.039  1   19.8   ? 133  TYR B CA  1 
ATOM   5088 C  C   . TYR B 1 141 ? 30.647  -12.204 18.922  1   19.609 ? 133  TYR B C   1 
ATOM   5089 O  O   . TYR B 1 141 ? 30.103  -11.29  19.535  1   22.338 ? 133  TYR B O   1 
ATOM   5090 C  CB  . TYR B 1 141 ? 29.011  -13.905 17.99   1   19.276 ? 133  TYR B CB  1 
ATOM   5091 C  CG  . TYR B 1 141 ? 28.646  -15.386 17.894  1   20.044 ? 133  TYR B CG  1 
ATOM   5092 C  CD1 . TYR B 1 141 ? 27.777  -15.976 18.818  1   19.489 ? 133  TYR B CD1 1 
ATOM   5093 C  CD2 . TYR B 1 141 ? 29.178  -16.188 16.866  1   21.293 ? 133  TYR B CD2 1 
ATOM   5094 C  CE1 . TYR B 1 141 ? 27.46   -17.336 18.74   1   19.364 ? 133  TYR B CE1 1 
ATOM   5095 C  CE2 . TYR B 1 141 ? 28.876  -17.554 16.78   1   22.427 ? 133  TYR B CE2 1 
ATOM   5096 C  CZ  . TYR B 1 141 ? 27.99   -18.115 17.715  1   19.856 ? 133  TYR B CZ  1 
ATOM   5097 O  OH  . TYR B 1 141 ? 27.608  -19.441 17.696  1   21.282 ? 133  TYR B OH  1 
ATOM   5098 N  N   . GLY B 1 142 ? 31.706  -12.049 18.108  1   19.964 ? 134  GLY B N   1 
ATOM   5099 C  CA  . GLY B 1 142 ? 32.385  -10.772 17.932  1   21.135 ? 134  GLY B CA  1 
ATOM   5100 C  C   . GLY B 1 142 ? 32.002  -10.087 16.627  1   19.474 ? 134  GLY B C   1 
ATOM   5101 O  O   . GLY B 1 142 ? 30.83   -9.835  16.336  1   20.103 ? 134  GLY B O   1 
ATOM   5102 N  N   . LEU B 1 143 ? 33.031  -9.712  15.873  1   20.107 ? 135  LEU B N   1 
ATOM   5103 C  CA  . LEU B 1 143 ? 32.853  -8.945  14.653  1   20.458 ? 135  LEU B CA  1 
ATOM   5104 C  C   . LEU B 1 143 ? 32.156  -9.757  13.567  1   20.324 ? 135  LEU B C   1 
ATOM   5105 O  O   . LEU B 1 143 ? 32.33   -10.965 13.481  1   21.355 ? 135  LEU B O   1 
ATOM   5106 C  CB  . LEU B 1 143 ? 34.233  -8.538  14.112  1   21.863 ? 135  LEU B CB  1 
ATOM   5107 C  CG  . LEU B 1 143 ? 35.075  -7.571  14.923  1   25.687 ? 135  LEU B CG  1 
ATOM   5108 C  CD1 . LEU B 1 143 ? 36.281  -7.233  14.001  1   24.527 ? 135  LEU B CD1 1 
ATOM   5109 C  CD2 . LEU B 1 143 ? 34.339  -6.255  15.331  1   23.737 ? 135  LEU B CD2 1 
ATOM   5110 N  N   . TYR B 1 144 ? 31.465  -9.036  12.683  1   20.265 ? 136  TYR B N   1 
ATOM   5111 C  CA  . TYR B 1 144 ? 30.881  -9.549  11.459  1   20.221 ? 136  TYR B CA  1 
ATOM   5112 C  C   . TYR B 1 144 ? 31.879  -10.452 10.743  1   22.137 ? 136  TYR B C   1 
ATOM   5113 O  O   . TYR B 1 144 ? 32.974  -10.027 10.363  1   20.124 ? 136  TYR B O   1 
ATOM   5114 C  CB  . TYR B 1 144 ? 30.516  -8.359  10.545  1   19.448 ? 136  TYR B CB  1 
ATOM   5115 C  CG  . TYR B 1 144 ? 29.88   -8.773  9.231   1   19.959 ? 136  TYR B CG  1 
ATOM   5116 C  CD1 . TYR B 1 144 ? 28.533  -9.172  9.195   1   19.682 ? 136  TYR B CD1 1 
ATOM   5117 C  CD2 . TYR B 1 144 ? 30.596  -8.757  8.029   1   18.13  ? 136  TYR B CD2 1 
ATOM   5118 C  CE1 . TYR B 1 144 ? 27.935  -9.534  7.998   1   22.438 ? 136  TYR B CE1 1 
ATOM   5119 C  CE2 . TYR B 1 144 ? 30.004  -9.112  6.829   1   20.372 ? 136  TYR B CE2 1 
ATOM   5120 C  CZ  . TYR B 1 144 ? 28.682  -9.527  6.822   1   22.308 ? 136  TYR B CZ  1 
ATOM   5121 O  OH  . TYR B 1 144 ? 28.072  -9.882  5.651   1   27.063 ? 136  TYR B OH  1 
ATOM   5122 N  N   . ARG B 1 145 ? 31.468  -11.715 10.549  1   18.542 ? 137  ARG B N   1 
ATOM   5123 C  CA  . ARG B 1 145 ? 32.201  -12.707 9.773   1   18.169 ? 137  ARG B CA  1 
ATOM   5124 C  C   . ARG B 1 145 ? 33.651  -12.896 10.261  1   19.351 ? 137  ARG B C   1 
ATOM   5125 O  O   . ARG B 1 145 ? 34.536  -13.192 9.456   1   18.802 ? 137  ARG B O   1 
ATOM   5126 C  CB  . ARG B 1 145 ? 32.114  -12.414 8.268   1   17.821 ? 137  ARG B CB  1 
ATOM   5127 C  CG  . ARG B 1 145 ? 30.66   -12.467 7.79    1   16.283 ? 137  ARG B CG  1 
ATOM   5128 C  CD  . ARG B 1 145 ? 30.684  -12.451 6.248   1   19.205 ? 137  ARG B CD  1 
ATOM   5129 N  NE  . ARG B 1 145 ? 31.221  -13.719 5.734   1   19.107 ? 137  ARG B NE  1 
ATOM   5130 C  CZ  . ARG B 1 145 ? 31.057  -14.143 4.477   1   20.409 ? 137  ARG B CZ  1 
ATOM   5131 N  NH1 . ARG B 1 145 ? 30.44   -13.35  3.596   1   20.791 ? 137  ARG B NH1 1 
ATOM   5132 N  NH2 . ARG B 1 145 ? 31.451  -15.372 4.175   1   21.04  ? 137  ARG B NH2 1 
ATOM   5133 N  N   . ASN B 1 146 ? 33.878  -12.765 11.584  1   18.148 ? 138  ASN B N   1 
ATOM   5134 C  CA  . ASN B 1 146 ? 35.233  -12.996 12.072  1   17.537 ? 138  ASN B CA  1 
ATOM   5135 C  C   . ASN B 1 146 ? 35.196  -13.952 13.271  1   16.866 ? 138  ASN B C   1 
ATOM   5136 O  O   . ASN B 1 146 ? 35.207  -13.518 14.442  1   17.478 ? 138  ASN B O   1 
ATOM   5137 C  CB  . ASN B 1 146 ? 35.959  -11.699 12.41   1   17.661 ? 138  ASN B CB  1 
ATOM   5138 C  CG  . ASN B 1 146 ? 37.414  -12.021 12.685  1   19.364 ? 138  ASN B CG  1 
ATOM   5139 O  OD1 . ASN B 1 146 ? 37.77   -13.204 12.801  1   21.549 ? 138  ASN B OD1 1 
ATOM   5140 N  ND2 . ASN B 1 146 ? 38.277  -11.021 12.795  1   19.03  ? 138  ASN B ND2 1 
ATOM   5141 N  N   . PRO B 1 147 ? 35.192  -15.285 13.004  1   19.589 ? 139  PRO B N   1 
ATOM   5142 C  CA  . PRO B 1 147 ? 35.271  -16.308 14.049  1   19.106 ? 139  PRO B CA  1 
ATOM   5143 C  C   . PRO B 1 147 ? 36.442  -16.196 15.036  1   19.442 ? 139  PRO B C   1 
ATOM   5144 O  O   . PRO B 1 147 ? 36.317  -16.607 16.191  1   21.347 ? 139  PRO B O   1 
ATOM   5145 C  CB  . PRO B 1 147 ? 35.357  -17.616 13.257  1   20.79  ? 139  PRO B CB  1 
ATOM   5146 C  CG  . PRO B 1 147 ? 34.513  -17.24  12.023  1   21.339 ? 139  PRO B CG  1 
ATOM   5147 C  CD  . PRO B 1 147 ? 35.026  -15.876 11.665  1   18.547 ? 139  PRO B CD  1 
ATOM   5148 N  N   . TYR B 1 148 ? 37.544  -15.55  14.631  1   20.66  ? 140  TYR B N   1 
ATOM   5149 C  CA  . TYR B 1 148 ? 38.677  -15.32  15.535  1   21.144 ? 140  TYR B CA  1 
ATOM   5150 C  C   . TYR B 1 148 ? 38.291  -14.401 16.687  1   19.727 ? 140  TYR B C   1 
ATOM   5151 O  O   . TYR B 1 148 ? 38.992  -14.414 17.705  1   23.538 ? 140  TYR B O   1 
ATOM   5152 C  CB  . TYR B 1 148 ? 39.948  -14.868 14.779  1   21.959 ? 140  TYR B CB  1 
ATOM   5153 C  CG  . TYR B 1 148 ? 40.342  -15.914 13.747  1   21.49  ? 140  TYR B CG  1 
ATOM   5154 C  CD1 . TYR B 1 148 ? 41.052  -17.061 14.122  1   22.179 ? 140  TYR B CD1 1 
ATOM   5155 C  CD2 . TYR B 1 148 ? 39.972  -15.777 12.396  1   20.36  ? 140  TYR B CD2 1 
ATOM   5156 C  CE1 . TYR B 1 148 ? 41.378  -18.061 13.203  1   21.636 ? 140  TYR B CE1 1 
ATOM   5157 C  CE2 . TYR B 1 148 ? 40.319  -16.754 11.469  1   21.58  ? 140  TYR B CE2 1 
ATOM   5158 C  CZ  . TYR B 1 148 ? 40.986  -17.906 11.873  1   22.086 ? 140  TYR B CZ  1 
ATOM   5159 O  OH  . TYR B 1 148 ? 41.291  -18.88  10.948  1   23.871 ? 140  TYR B OH  1 
ATOM   5160 N  N   . THR B 1 149 ? 37.212  -13.606 16.545  1   18.614 ? 141  THR B N   1 
ATOM   5161 C  CA  . THR B 1 149 ? 36.748  -12.714 17.606  1   20.756 ? 141  THR B CA  1 
ATOM   5162 C  C   . THR B 1 149 ? 35.541  -13.265 18.382  1   22.059 ? 141  THR B C   1 
ATOM   5163 O  O   . THR B 1 149 ? 35.116  -12.619 19.335  1   21.872 ? 141  THR B O   1 
ATOM   5164 C  CB  . THR B 1 149 ? 36.449  -11.328 17.025  1   22.544 ? 141  THR B CB  1 
ATOM   5165 O  OG1 . THR B 1 149 ? 35.312  -11.467 16.157  1   21.272 ? 141  THR B OG1 1 
ATOM   5166 C  CG2 . THR B 1 149 ? 37.689  -10.722 16.363  1   21.872 ? 141  THR B CG2 1 
ATOM   5167 N  N   . HIS B 1 150 ? 35.077  -14.466 18.036  1   19.849 ? 142  HIS B N   1 
ATOM   5168 C  CA  . HIS B 1 150 ? 34.02   -15.131 18.785  1   21.508 ? 142  HIS B CA  1 
ATOM   5169 C  C   . HIS B 1 150 ? 34.606  -15.811 20.013  1   22.265 ? 142  HIS B C   1 
ATOM   5170 O  O   . HIS B 1 150 ? 35.818  -16.028 20.079  1   22.268 ? 142  HIS B O   1 
ATOM   5171 C  CB  . HIS B 1 150 ? 33.255  -16.168 17.95   1   20.366 ? 142  HIS B CB  1 
ATOM   5172 C  CG  . HIS B 1 150 ? 32.676  -15.65  16.672  1   20.037 ? 142  HIS B CG  1 
ATOM   5173 N  ND1 . HIS B 1 150 ? 32.403  -14.316 16.48   1   19.889 ? 142  HIS B ND1 1 
ATOM   5174 C  CD2 . HIS B 1 150 ? 32.332  -16.283 15.519  1   21.763 ? 142  HIS B CD2 1 
ATOM   5175 C  CE1 . HIS B 1 150 ? 31.953  -14.147 15.24   1   20.519 ? 142  HIS B CE1 1 
ATOM   5176 N  NE2 . HIS B 1 150 ? 31.872  -15.325 14.645  1   18.874 ? 142  HIS B NE2 1 
ATOM   5177 N  N   . HIS B 1 151 ? 33.713  -16.165 20.947  1   21.399 ? 143  HIS B N   1 
ATOM   5178 C  CA  . HIS B 1 151 ? 34.133  -16.931 22.098  1   20.14  ? 143  HIS B CA  1 
ATOM   5179 C  C   . HIS B 1 151 ? 34.736  -18.254 21.598  1   21.609 ? 143  HIS B C   1 
ATOM   5180 O  O   . HIS B 1 151 ? 34.217  -18.872 20.66   1   20.71  ? 143  HIS B O   1 
ATOM   5181 C  CB  . HIS B 1 151 ? 32.91   -17.267 22.972  1   19.636 ? 143  HIS B CB  1 
ATOM   5182 C  CG  . HIS B 1 151 ? 33.287  -17.874 24.286  1   22.375 ? 143  HIS B CG  1 
ATOM   5183 N  ND1 . HIS B 1 151 ? 33.588  -19.206 24.402  1   23.422 ? 143  HIS B ND1 1 
ATOM   5184 C  CD2 . HIS B 1 151 ? 33.317  -17.387 25.538  1   23.326 ? 143  HIS B CD2 1 
ATOM   5185 C  CE1 . HIS B 1 151 ? 33.843  -19.505 25.674  1   25.555 ? 143  HIS B CE1 1 
ATOM   5186 N  NE2 . HIS B 1 151 ? 33.645  -18.424 26.381  1   23.523 ? 143  HIS B NE2 1 
ATOM   5187 N  N   . PRO B 1 152 ? 35.881  -18.7   22.178  1   24.795 ? 144  PRO B N   1 
ATOM   5188 C  CA  . PRO B 1 152 ? 36.531  -19.943 21.756  1   26.79  ? 144  PRO B CA  1 
ATOM   5189 C  C   . PRO B 1 152 ? 35.596  -21.145 21.581  1   24.849 ? 144  PRO B C   1 
ATOM   5190 O  O   . PRO B 1 152 ? 35.743  -21.882 20.609  1   26.553 ? 144  PRO B O   1 
ATOM   5191 C  CB  . PRO B 1 152 ? 37.625  -20.182 22.811  1   25.397 ? 144  PRO B CB  1 
ATOM   5192 C  CG  . PRO B 1 152 ? 37.69   -18.952 23.654  1   28.604 ? 144  PRO B CG  1 
ATOM   5193 C  CD  . PRO B 1 152 ? 36.58   -17.998 23.271  1   23.659 ? 144  PRO B CD  1 
ATOM   5194 N  N   . CYS B 1 153 ? 34.58   -21.277 22.458  1   25.059 ? 145  CYS B N   1 
ATOM   5195 C  CA  . CYS B 1 153 ? 33.635  -22.4   22.431  1   25.792 ? 145  CYS B CA  1 
ATOM   5196 C  C   . CYS B 1 153 ? 32.723  -22.386 21.205  1   26.819 ? 145  CYS B C   1 
ATOM   5197 O  O   . CYS B 1 153 ? 32.161  -23.439 20.888  1   26.932 ? 145  CYS B O   1 
ATOM   5198 C  CB  . CYS B 1 153 ? 32.777  -22.478 23.683  1   29.611 ? 145  CYS B CB  1 
ATOM   5199 S  SG  . CYS B 1 153 ? 33.716  -23.176 25.076  1   42.453 ? 145  CYS B SG  1 
ATOM   5200 N  N   . VAL B 1 154 ? 32.589  -21.231 20.526  1   23.353 ? 146  VAL B N   1 
ATOM   5201 C  CA  . VAL B 1 154 ? 31.651  -21.122 19.411  1   22.383 ? 146  VAL B CA  1 
ATOM   5202 C  C   . VAL B 1 154 ? 32.337  -20.819 18.075  1   22.954 ? 146  VAL B C   1 
ATOM   5203 O  O   . VAL B 1 154 ? 31.657  -20.586 17.077  1   21.434 ? 146  VAL B O   1 
ATOM   5204 C  CB  . VAL B 1 154 ? 30.494  -20.136 19.669  1   23.714 ? 146  VAL B CB  1 
ATOM   5205 C  CG1 . VAL B 1 154 ? 29.721  -20.481 20.941  1   27.716 ? 146  VAL B CG1 1 
ATOM   5206 C  CG2 . VAL B 1 154 ? 30.954  -18.673 19.655  1   23.078 ? 146  VAL B CG2 1 
ATOM   5207 N  N   . ARG B 1 155 ? 33.674  -20.844 18.031  1   22.238 ? 147  ARG B N   1 
ATOM   5208 C  CA  . ARG B 1 155 ? 34.406  -20.482 16.82   1   22.519 ? 147  ARG B CA  1 
ATOM   5209 C  C   . ARG B 1 155 ? 34.057  -21.37  15.654  1   21.211 ? 147  ARG B C   1 
ATOM   5210 O  O   . ARG B 1 155 ? 34.015  -20.89  14.51   1   22.706 ? 147  ARG B O   1 
ATOM   5211 C  CB  . ARG B 1 155 ? 35.93   -20.602 17.003  1   24.755 ? 147  ARG B CB  1 
ATOM   5212 C  CG  . ARG B 1 155 ? 36.368  -19.384 17.782  1   27.324 ? 147  ARG B CG  1 
ATOM   5213 C  CD  . ARG B 1 155 ? 37.867  -19.142 17.725  1   31.214 ? 147  ARG B CD  1 
ATOM   5214 N  NE  . ARG B 1 155 ? 37.82   -17.961 18.594  1   31.852 ? 147  ARG B NE  1 
ATOM   5215 C  CZ  . ARG B 1 155 ? 38.745  -17.635 19.47   1   39.009 ? 147  ARG B CZ  1 
ATOM   5216 N  NH1 . ARG B 1 155 ? 39.847  -18.384 19.521  1   45.749 ? 147  ARG B NH1 1 
ATOM   5217 N  NH2 . ARG B 1 155 ? 38.571  -16.568 20.242  1   32.337 ? 147  ARG B NH2 1 
ATOM   5218 N  N   . GLN B 1 156 ? 33.746  -22.658 15.951  1   22.873 ? 148  GLN B N   1 
ATOM   5219 C  CA  . GLN B 1 156 ? 33.491  -23.625 14.904  1   26.128 ? 148  GLN B CA  1 
ATOM   5220 C  C   . GLN B 1 156 ? 31.988  -23.874 14.76   1   27.622 ? 148  GLN B C   1 
ATOM   5221 O  O   . GLN B 1 156 ? 31.573  -24.944 14.325  1   28.034 ? 148  GLN B O   1 
ATOM   5222 C  CB  . GLN B 1 156 ? 34.317  -24.877 15.202  1   29.209 ? 148  GLN B CB  1 
ATOM   5223 C  CG  . GLN B 1 156 ? 34.801  -25.549 13.935  1   32.132 ? 148  GLN B CG  1 
ATOM   5224 C  CD  . GLN B 1 156 ? 35.744  -26.711 14.176  1   38.412 ? 148  GLN B CD  1 
ATOM   5225 O  OE1 . GLN B 1 156 ? 35.96   -27.5   13.256  1   40.162 ? 148  GLN B OE1 1 
ATOM   5226 N  NE2 . GLN B 1 156 ? 36.302  -26.816 15.378  1   31.484 ? 148  GLN B NE2 1 
ATOM   5227 N  N   . THR B 1 157 ? 31.179  -22.861 15.082  1   22.858 ? 149  THR B N   1 
ATOM   5228 C  CA  . THR B 1 157 ? 29.745  -22.926 14.836  1   20.326 ? 149  THR B CA  1 
ATOM   5229 C  C   . THR B 1 157 ? 29.468  -22.25  13.486  1   19.575 ? 149  THR B C   1 
ATOM   5230 O  O   . THR B 1 157 ? 30.309  -21.525 12.956  1   19.806 ? 149  THR B O   1 
ATOM   5231 C  CB  . THR B 1 157 ? 28.922  -22.26  15.953  1   20.277 ? 149  THR B CB  1 
ATOM   5232 O  OG1 . THR B 1 157 ? 29.344  -20.89  16.02   1   20.795 ? 149  THR B OG1 1 
ATOM   5233 C  CG2 . THR B 1 157 ? 29.048  -22.999 17.282  1   24.692 ? 149  THR B CG2 1 
ATOM   5234 N  N   . VAL B 1 158 ? 28.247  -22.452 12.992  1   20.592 ? 150  VAL B N   1 
ATOM   5235 C  CA  . VAL B 1 158 ? 27.706  -21.598 11.945  1   20.213 ? 150  VAL B CA  1 
ATOM   5236 C  C   . VAL B 1 158 ? 27.384  -20.255 12.612  1   20.252 ? 150  VAL B C   1 
ATOM   5237 O  O   . VAL B 1 158 ? 26.633  -20.208 13.596  1   21.15  ? 150  VAL B O   1 
ATOM   5238 C  CB  . VAL B 1 158 ? 26.486  -22.309 11.325  1   22.111 ? 150  VAL B CB  1 
ATOM   5239 C  CG1 . VAL B 1 158 ? 25.677  -21.355 10.451  1   20.034 ? 150  VAL B CG1 1 
ATOM   5240 C  CG2 . VAL B 1 158 ? 26.946  -23.539 10.535  1   20.333 ? 150  VAL B CG2 1 
ATOM   5241 N  N   . GLU B 1 159 ? 27.997  -19.175 12.088  1   18.228 ? 151  GLU B N   1 
ATOM   5242 C  CA  . GLU B 1 159 ? 27.923  -17.883 12.767  1   18.346 ? 151  GLU B CA  1 
ATOM   5243 C  C   . GLU B 1 159 ? 26.849  -16.99  12.142  1   20.066 ? 151  GLU B C   1 
ATOM   5244 O  O   . GLU B 1 159 ? 26.656  -15.848 12.577  1   20.205 ? 151  GLU B O   1 
ATOM   5245 C  CB  . GLU B 1 159 ? 29.284  -17.16  12.762  1   21.318 ? 151  GLU B CB  1 
ATOM   5246 C  CG  . GLU B 1 159 ? 29.824  -17.061 11.331  1   22.606 ? 151  GLU B CG  1 
ATOM   5247 C  CD  . GLU B 1 159 ? 30.723  -15.875 11.048  1   26.145 ? 151  GLU B CD  1 
ATOM   5248 O  OE1 . GLU B 1 159 ? 31.216  -15.2   12.008  1   24.866 ? 151  GLU B OE1 1 
ATOM   5249 O  OE2 . GLU B 1 159 ? 30.893  -15.67  9.8     1   24.971 ? 151  GLU B OE2 1 
ATOM   5250 N  N   . SER B 1 160 ? 26.169  -17.494 11.098  1   18.212 ? 152  SER B N   1 
ATOM   5251 C  CA  . SER B 1 160 ? 25.124  -16.751 10.407  1   18.714 ? 152  SER B CA  1 
ATOM   5252 C  C   . SER B 1 160 ? 24.019  -16.297 11.377  1   18.195 ? 152  SER B C   1 
ATOM   5253 O  O   . SER B 1 160 ? 23.505  -17.076 12.197  1   19.552 ? 152  SER B O   1 
ATOM   5254 C  CB  . SER B 1 160 ? 24.53   -17.611 9.304   1   20.894 ? 152  SER B CB  1 
ATOM   5255 O  OG  . SER B 1 160 ? 23.379  -16.928 8.845   1   19.401 ? 152  SER B OG  1 
ATOM   5256 N  N   . THR B 1 161 ? 23.611  -15.018 11.239  1   19     ? 153  THR B N   1 
ATOM   5257 C  CA  . THR B 1 161 ? 22.439  -14.501 11.964  1   19.457 ? 153  THR B CA  1 
ATOM   5258 C  C   . THR B 1 161 ? 21.207  -14.528 11.057  1   17.42  ? 153  THR B C   1 
ATOM   5259 O  O   . THR B 1 161 ? 20.158  -14.049 11.473  1   19.255 ? 153  THR B O   1 
ATOM   5260 C  CB  . THR B 1 161 ? 22.719  -13.078 12.465  1   19.948 ? 153  THR B CB  1 
ATOM   5261 O  OG1 . THR B 1 161 ? 23.228  -12.337 11.359  1   18.875 ? 153  THR B OG1 1 
ATOM   5262 C  CG2 . THR B 1 161 ? 23.729  -13.066 13.601  1   19.404 ? 153  THR B CG2 1 
ATOM   5263 N  N   . ALA B 1 162 ? 21.344  -15.02  9.818   1   17.27  ? 154  ALA B N   1 
ATOM   5264 C  CA  . ALA B 1 162 ? 20.199  -15.293 8.946   1   17.576 ? 154  ALA B CA  1 
ATOM   5265 C  C   . ALA B 1 162 ? 19.251  -14.092 8.896   1   18.101 ? 154  ALA B C   1 
ATOM   5266 O  O   . ALA B 1 162 ? 18.054  -14.242 9.162   1   17.808 ? 154  ALA B O   1 
ATOM   5267 C  CB  . ALA B 1 162 ? 19.445  -16.544 9.41    1   15.892 ? 154  ALA B CB  1 
ATOM   5268 N  N   . ASN B 1 163 ? 19.788  -12.923 8.492   1   16.501 ? 155  ASN B N   1 
ATOM   5269 C  CA  . ASN B 1 163 ? 19.063  -11.687 8.749   1   17.737 ? 155  ASN B CA  1 
ATOM   5270 C  C   . ASN B 1 163 ? 18.91   -10.811 7.5     1   18.107 ? 155  ASN B C   1 
ATOM   5271 O  O   . ASN B 1 163 ? 18.578  -9.645  7.679   1   21.441 ? 155  ASN B O   1 
ATOM   5272 C  CB  . ASN B 1 163 ? 19.793  -10.888 9.832   1   18.234 ? 155  ASN B CB  1 
ATOM   5273 C  CG  . ASN B 1 163 ? 21.163  -10.367 9.4     1   19.128 ? 155  ASN B CG  1 
ATOM   5274 O  OD1 . ASN B 1 163 ? 21.639  -10.711 8.293   1   19.46  ? 155  ASN B OD1 1 
ATOM   5275 N  ND2 . ASN B 1 163 ? 21.786  -9.559  10.256  1   19.092 ? 155  ASN B ND2 1 
ATOM   5276 N  N   . THR B 1 164 ? 19.158  -11.33  6.281   1   18.564 ? 156  THR B N   1 
ATOM   5277 C  CA  . THR B 1 164 ? 19.261  -10.506 5.082   1   18.09  ? 156  THR B CA  1 
ATOM   5278 C  C   . THR B 1 164 ? 18.041  -10.64  4.166   1   18.628 ? 156  THR B C   1 
ATOM   5279 O  O   . THR B 1 164 ? 17.556  -9.634  3.679   1   19.292 ? 156  THR B O   1 
ATOM   5280 C  CB  . THR B 1 164 ? 20.535  -10.914 4.293   1   24.309 ? 156  THR B CB  1 
ATOM   5281 O  OG1 . THR B 1 164 ? 21.605  -10.591 5.191   1   28.786 ? 156  THR B OG1 1 
ATOM   5282 C  CG2 . THR B 1 164 ? 20.682  -10.202 2.969   1   32.547 ? 156  THR B CG2 1 
ATOM   5283 N  N   . ASN B 1 165 ? 17.587  -11.856 3.87    1   18.843 ? 157  ASN B N   1 
ATOM   5284 C  CA  . ASN B 1 165 ? 16.51   -11.996 2.885   1   18.904 ? 157  ASN B CA  1 
ATOM   5285 C  C   . ASN B 1 165 ? 15.771  -13.31  3.115   1   18.911 ? 157  ASN B C   1 
ATOM   5286 O  O   . ASN B 1 165 ? 16.21   -14.167 3.87    1   18.327 ? 157  ASN B O   1 
ATOM   5287 C  CB  . ASN B 1 165 ? 17.091  -11.916 1.469   1   18.307 ? 157  ASN B CB  1 
ATOM   5288 C  CG  . ASN B 1 165 ? 16.089  -11.695 0.355   1   20.122 ? 157  ASN B CG  1 
ATOM   5289 O  OD1 . ASN B 1 165 ? 14.91   -11.398 0.597   1   20.311 ? 157  ASN B OD1 1 
ATOM   5290 N  ND2 . ASN B 1 165 ? 16.546  -11.852 -0.885  1   20.32  ? 157  ASN B ND2 1 
ATOM   5291 N  N   . VAL B 1 166 ? 14.623  -13.461 2.444   1   16.187 ? 158  VAL B N   1 
ATOM   5292 C  CA  . VAL B 1 166 ? 13.807  -14.654 2.592   1   17.429 ? 158  VAL B CA  1 
ATOM   5293 C  C   . VAL B 1 166 ? 13.37   -15.11  1.206   1   18.435 ? 158  VAL B C   1 
ATOM   5294 O  O   . VAL B 1 166 ? 13.395  -14.308 0.248   1   18.397 ? 158  VAL B O   1 
ATOM   5295 C  CB  . VAL B 1 166 ? 12.581  -14.458 3.504   1   19.597 ? 158  VAL B CB  1 
ATOM   5296 C  CG1 . VAL B 1 166 ? 12.989  -14.127 4.935   1   17.691 ? 158  VAL B CG1 1 
ATOM   5297 C  CG2 . VAL B 1 166 ? 11.597  -13.42  2.962   1   19.857 ? 158  VAL B CG2 1 
ATOM   5298 N  N   . VAL B 1 167 ? 13.002  -16.402 1.122   1   19.666 ? 159  VAL B N   1 
ATOM   5299 C  CA  . VAL B 1 167 ? 12.49   -16.957 -0.126  1   20.221 ? 159  VAL B CA  1 
ATOM   5300 C  C   . VAL B 1 167 ? 11.623  -18.163 0.205   1   21.24  ? 159  VAL B C   1 
ATOM   5301 O  O   . VAL B 1 167 ? 11.882  -18.837 1.193   1   21.914 ? 159  VAL B O   1 
ATOM   5302 C  CB  . VAL B 1 167 ? 13.639  -17.321 -1.107  1   20.554 ? 159  VAL B CB  1 
ATOM   5303 C  CG1 . VAL B 1 167 ? 14.525  -18.475 -0.607  1   18.568 ? 159  VAL B CG1 1 
ATOM   5304 C  CG2 . VAL B 1 167 ? 13.093  -17.627 -2.516  1   22.299 ? 159  VAL B CG2 1 
ATOM   5305 N  N   . MET B 1 168 ? 10.586  -18.387 -0.631  1   20.663 ? 160  MET B N   1 
ATOM   5306 C  CA  . MET B 1 168 ? 9.79    -19.592 -0.596  1   20.625 ? 160  MET B CA  1 
ATOM   5307 C  C   . MET B 1 168 ? 10.12   -20.355 -1.884  1   21.755 ? 160  MET B C   1 
ATOM   5308 O  O   . MET B 1 168 ? 9.876   -19.857 -2.996  1   22.468 ? 160  MET B O   1 
ATOM   5309 C  CB  . MET B 1 168 ? 8.295   -19.225 -0.579  1   21.309 ? 160  MET B CB  1 
ATOM   5310 C  CG  . MET B 1 168 ? 7.386   -20.446 -0.605  1   22.642 ? 160  MET B CG  1 
ATOM   5311 S  SD  . MET B 1 168 ? 7.391   -21.319 0.972   1   26.516 ? 160  MET B SD  1 
ATOM   5312 C  CE  . MET B 1 168 ? 6.329   -20.212 1.907   1   27.131 ? 160  MET B CE  1 
ATOM   5313 N  N   . HIS B 1 169 ? 10.701  -21.55  -1.702  1   19.553 ? 161  HIS B N   1 
ATOM   5314 C  CA  . HIS B 1 169 ? 11.131  -22.348 -2.86   1   19.779 ? 161  HIS B CA  1 
ATOM   5315 C  C   . HIS B 1 169 ? 10.849  -23.814 -2.556  1   18.075 ? 161  HIS B C   1 
ATOM   5316 O  O   . HIS B 1 169 ? 11.216  -24.328 -1.474  1   21.536 ? 161  HIS B O   1 
ATOM   5317 C  CB  . HIS B 1 169 ? 12.628  -22.112 -3.173  1   20.004 ? 161  HIS B CB  1 
ATOM   5318 C  CG  . HIS B 1 169 ? 13      -22.934 -4.381  1   19.81  ? 161  HIS B CG  1 
ATOM   5319 N  ND1 . HIS B 1 169 ? 12.582  -22.539 -5.643  1   20.582 ? 161  HIS B ND1 1 
ATOM   5320 C  CD2 . HIS B 1 169 ? 13.613  -24.124 -4.525  1   20.226 ? 161  HIS B CD2 1 
ATOM   5321 C  CE1 . HIS B 1 169 ? 12.955  -23.449 -6.53   1   21.183 ? 161  HIS B CE1 1 
ATOM   5322 N  NE2 . HIS B 1 169 ? 13.558  -24.44  -5.894  1   20.046 ? 161  HIS B NE2 1 
ATOM   5323 N  N   . ALA B 1 170 ? 10.204  -24.51  -3.504  1   22.089 ? 162  ALA B N   1 
ATOM   5324 C  CA  . ALA B 1 170 ? 9.94    -25.943 -3.365  1   22.761 ? 162  ALA B CA  1 
ATOM   5325 C  C   . ALA B 1 170 ? 9.208   -26.24  -2.056  1   23.515 ? 162  ALA B C   1 
ATOM   5326 O  O   . ALA B 1 170 ? 9.483   -27.237 -1.406  1   22.641 ? 162  ALA B O   1 
ATOM   5327 C  CB  . ALA B 1 170 ? 11.235  -26.754 -3.51   1   22.305 ? 162  ALA B CB  1 
ATOM   5328 N  N   . GLY B 1 171 ? 8.265   -25.351 -1.688  1   22.932 ? 163  GLY B N   1 
ATOM   5329 C  CA  . GLY B 1 171 ? 7.435   -25.503 -0.502  1   23.376 ? 163  GLY B CA  1 
ATOM   5330 C  C   . GLY B 1 171 ? 8.154   -25.205 0.803   1   24.851 ? 163  GLY B C   1 
ATOM   5331 O  O   . GLY B 1 171 ? 7.596   -25.471 1.866   1   24.699 ? 163  GLY B O   1 
ATOM   5332 N  N   . ARG B 1 172 ? 9.37    -24.641 0.73    1   22.537 ? 164  ARG B N   1 
ATOM   5333 C  CA  . ARG B 1 172 ? 10.165  -24.416 1.937   1   20.372 ? 164  ARG B CA  1 
ATOM   5334 C  C   . ARG B 1 172 ? 10.451  -22.918 2.059   1   21.247 ? 164  ARG B C   1 
ATOM   5335 O  O   . ARG B 1 172 ? 10.792  -22.284 1.079   1   20.304 ? 164  ARG B O   1 
ATOM   5336 C  CB  . ARG B 1 172 ? 11.499  -25.163 1.921   1   22.293 ? 164  ARG B CB  1 
ATOM   5337 C  CG  . ARG B 1 172 ? 11.345  -26.658 1.663   1   26.325 ? 164  ARG B CG  1 
ATOM   5338 C  CD  . ARG B 1 172 ? 12.731  -27.201 1.947   1   32.234 ? 164  ARG B CD  1 
ATOM   5339 N  NE  . ARG B 1 172 ? 12.684  -28.653 1.801   1   34.506 ? 164  ARG B NE  1 
ATOM   5340 C  CZ  . ARG B 1 172 ? 12.687  -29.505 2.811   1   36.019 ? 164  ARG B CZ  1 
ATOM   5341 N  NH1 . ARG B 1 172 ? 12.792  -29.097 4.076   1   28.84  ? 164  ARG B NH1 1 
ATOM   5342 N  NH2 . ARG B 1 172 ? 12.564  -30.8   2.539   1   40.209 ? 164  ARG B NH2 1 
ATOM   5343 N  N   . PHE B 1 173 ? 10.27   -22.378 3.277   1   19.39  ? 165  PHE B N   1 
ATOM   5344 C  CA  . PHE B 1 173 ? 10.46   -20.96  3.523   1   20.762 ? 165  PHE B CA  1 
ATOM   5345 C  C   . PHE B 1 173 ? 11.813  -20.793 4.209   1   19.738 ? 165  PHE B C   1 
ATOM   5346 O  O   . PHE B 1 173 ? 12.061  -21.399 5.264   1   20.496 ? 165  PHE B O   1 
ATOM   5347 C  CB  . PHE B 1 173 ? 9.301   -20.427 4.375   1   21.576 ? 165  PHE B CB  1 
ATOM   5348 C  CG  . PHE B 1 173 ? 9.434   -18.94  4.69    1   21.447 ? 165  PHE B CG  1 
ATOM   5349 C  CD1 . PHE B 1 173 ? 9.381   -17.979 3.667   1   22.562 ? 165  PHE B CD1 1 
ATOM   5350 C  CD2 . PHE B 1 173 ? 9.641   -18.516 6.005   1   21.484 ? 165  PHE B CD2 1 
ATOM   5351 C  CE1 . PHE B 1 173 ? 9.507   -16.616 3.952   1   22.844 ? 165  PHE B CE1 1 
ATOM   5352 C  CE2 . PHE B 1 173 ? 9.798   -17.16  6.29    1   23.044 ? 165  PHE B CE2 1 
ATOM   5353 C  CZ  . PHE B 1 173 ? 9.729   -16.219 5.272   1   21.606 ? 165  PHE B CZ  1 
ATOM   5354 N  N   . LEU B 1 174 ? 12.67   -19.961 3.607   1   20.089 ? 166  LEU B N   1 
ATOM   5355 C  CA  . LEU B 1 174 ? 14.062  -19.874 4.059   1   19.526 ? 166  LEU B CA  1 
ATOM   5356 C  C   . LEU B 1 174 ? 14.413  -18.455 4.51    1   19.991 ? 166  LEU B C   1 
ATOM   5357 O  O   . LEU B 1 174 ? 14.041  -17.514 3.817   1   19.075 ? 166  LEU B O   1 
ATOM   5358 C  CB  . LEU B 1 174 ? 14.946  -20.159 2.845   1   20.389 ? 166  LEU B CB  1 
ATOM   5359 C  CG  . LEU B 1 174 ? 15.323  -21.612 2.561   1   24.778 ? 166  LEU B CG  1 
ATOM   5360 C  CD1 . LEU B 1 174 ? 14.19   -22.555 2.567   1   22.961 ? 166  LEU B CD1 1 
ATOM   5361 C  CD2 . LEU B 1 174 ? 16.1    -21.658 1.248   1   27.424 ? 166  LEU B CD2 1 
ATOM   5362 N  N   . ALA B 1 175 ? 15.225  -18.342 5.587   1   19.465 ? 167  ALA B N   1 
ATOM   5363 C  CA  . ALA B 1 175 ? 15.864  -17.088 5.971   1   18.436 ? 167  ALA B CA  1 
ATOM   5364 C  C   . ALA B 1 175 ? 17.348  -17.233 5.623   1   17.752 ? 167  ALA B C   1 
ATOM   5365 O  O   . ALA B 1 175 ? 17.941  -18.282 5.923   1   18.615 ? 167  ALA B O   1 
ATOM   5366 C  CB  . ALA B 1 175 ? 15.691  -16.864 7.502   1   17.332 ? 167  ALA B CB  1 
ATOM   5367 N  N   . MET B 1 176 ? 17.935  -16.183 5.003   1   18.263 ? 168  MET B N   1 
ATOM   5368 C  CA  . MET B 1 176 ? 19.227  -16.292 4.336   1   17.404 ? 168  MET B CA  1 
ATOM   5369 C  C   . MET B 1 176 ? 20.177  -15.205 4.841   1   19.225 ? 168  MET B C   1 
ATOM   5370 O  O   . MET B 1 176 ? 19.759  -14.107 5.167   1   17.731 ? 168  MET B O   1 
ATOM   5371 C  CB  . MET B 1 176 ? 19.042  -16.136 2.817   1   18.863 ? 168  MET B CB  1 
ATOM   5372 C  CG  . MET B 1 176 ? 18.058  -17.222 2.267   1   15.832 ? 168  MET B CG  1 
ATOM   5373 S  SD  . MET B 1 176 ? 17.894  -17.043 0.48    1   20.127 ? 168  MET B SD  1 
ATOM   5374 C  CE  . MET B 1 176 ? 16.763  -15.632 0.453   1   18.447 ? 168  MET B CE  1 
ATOM   5375 N  N   . LYS B 1 177 ? 21.45   -15.563 4.934   1   17.393 ? 169  LYS B N   1 
ATOM   5376 C  CA  . LYS B 1 177 ? 22.553  -14.626 5.081   1   18.235 ? 169  LYS B CA  1 
ATOM   5377 C  C   . LYS B 1 177 ? 23.739  -15.319 4.412   1   19.067 ? 169  LYS B C   1 
ATOM   5378 O  O   . LYS B 1 177 ? 23.96   -16.516 4.632   1   18.444 ? 169  LYS B O   1 
ATOM   5379 C  CB  . LYS B 1 177 ? 22.77   -14.307 6.573   1   17.678 ? 169  LYS B CB  1 
ATOM   5380 C  CG  . LYS B 1 177 ? 23.792  -13.159 6.714   1   18.39  ? 169  LYS B CG  1 
ATOM   5381 C  CD  . LYS B 1 177 ? 24.083  -12.976 8.202   1   20.472 ? 169  LYS B CD  1 
ATOM   5382 C  CE  . LYS B 1 177 ? 25.056  -11.793 8.396   1   18.976 ? 169  LYS B CE  1 
ATOM   5383 N  NZ  . LYS B 1 177 ? 24.397  -10.52  7.921   1   18.128 ? 169  LYS B NZ  1 
ATOM   5384 N  N   . GLU B 1 178 ? 24.514  -14.533 3.667   1   18.568 ? 170  GLU B N   1 
ATOM   5385 C  CA  . GLU B 1 178 ? 25.484  -15.074 2.717   1   19.485 ? 170  GLU B CA  1 
ATOM   5386 C  C   . GLU B 1 178 ? 26.681  -15.779 3.356   1   19.126 ? 170  GLU B C   1 
ATOM   5387 O  O   . GLU B 1 178 ? 27.435  -16.385 2.581   1   19.86  ? 170  GLU B O   1 
ATOM   5388 C  CB  . GLU B 1 178 ? 25.928  -13.995 1.734   1   17.471 ? 170  GLU B CB  1 
ATOM   5389 C  CG  . GLU B 1 178 ? 26.788  -12.914 2.374   1   17.847 ? 170  GLU B CG  1 
ATOM   5390 C  CD  . GLU B 1 178 ? 26.627  -11.676 1.528   1   22.415 ? 170  GLU B CD  1 
ATOM   5391 O  OE1 . GLU B 1 178 ? 25.487  -11.117 1.47    1   22.496 ? 170  GLU B OE1 1 
ATOM   5392 O  OE2 . GLU B 1 178 ? 27.641  -11.27  0.948   1   22.471 ? 170  GLU B OE2 1 
ATOM   5393 N  N   . ASN B 1 179 ? 26.88   -15.668 4.692   1   17.831 ? 171  ASN B N   1 
ATOM   5394 C  CA  . ASN B 1 179 ? 27.964  -16.394 5.349   1   20.677 ? 171  ASN B CA  1 
ATOM   5395 C  C   . ASN B 1 179 ? 27.57   -17.801 5.84    1   19.814 ? 171  ASN B C   1 
ATOM   5396 O  O   . ASN B 1 179 ? 28.334  -18.44  6.58    1   19.681 ? 171  ASN B O   1 
ATOM   5397 C  CB  . ASN B 1 179 ? 28.59   -15.597 6.497   1   19.178 ? 171  ASN B CB  1 
ATOM   5398 C  CG  . ASN B 1 179 ? 27.595  -15.271 7.594   1   22.346 ? 171  ASN B CG  1 
ATOM   5399 O  OD1 . ASN B 1 179 ? 26.369  -15.277 7.368   1   20.097 ? 171  ASN B OD1 1 
ATOM   5400 N  ND2 . ASN B 1 179 ? 28.109  -15.024 8.795   1   19.706 ? 171  ASN B ND2 1 
ATOM   5401 N  N   . GLY B 1 180 ? 26.393  -18.306 5.466   1   17.344 ? 172  GLY B N   1 
ATOM   5402 C  CA  . GLY B 1 180 ? 26.05   -19.69  5.758   1   17.991 ? 172  GLY B CA  1 
ATOM   5403 C  C   . GLY B 1 180 ? 24.975  -20.177 4.793   1   18.146 ? 172  GLY B C   1 
ATOM   5404 O  O   . GLY B 1 180 ? 24.479  -19.42  3.981   1   18.072 ? 172  GLY B O   1 
ATOM   5405 N  N   . ASN B 1 181 ? 24.599  -21.454 4.91    1   19.002 ? 173  ASN B N   1 
ATOM   5406 C  CA  . ASN B 1 181 ? 23.378  -21.885 4.253   1   19.206 ? 173  ASN B CA  1 
ATOM   5407 C  C   . ASN B 1 181 ? 22.146  -21.306 4.981   1   18.341 ? 173  ASN B C   1 
ATOM   5408 O  O   . ASN B 1 181 ? 22.241  -20.745 6.08    1   19.577 ? 173  ASN B O   1 
ATOM   5409 C  CB  . ASN B 1 181 ? 23.363  -23.41  4.132   1   15.9   ? 173  ASN B CB  1 
ATOM   5410 C  CG  . ASN B 1 181 ? 24.155  -23.812 2.905   1   18.637 ? 173  ASN B CG  1 
ATOM   5411 O  OD1 . ASN B 1 181 ? 23.715  -23.546 1.784   1   19.272 ? 173  ASN B OD1 1 
ATOM   5412 N  ND2 . ASN B 1 181 ? 25.337  -24.395 3.094   1   19.979 ? 173  ASN B ND2 1 
ATOM   5413 N  N   . ALA B 1 182 ? 20.975  -21.477 4.356   1   20.913 ? 174  ALA B N   1 
ATOM   5414 C  CA  . ALA B 1 182 ? 19.734  -20.902 4.84    1   19.875 ? 174  ALA B CA  1 
ATOM   5415 C  C   . ALA B 1 182 ? 19.258  -21.689 6.068   1   23.883 ? 174  ALA B C   1 
ATOM   5416 O  O   . ALA B 1 182 ? 19.553  -22.888 6.243   1   20.895 ? 174  ALA B O   1 
ATOM   5417 C  CB  . ALA B 1 182 ? 18.664  -20.969 3.751   1   19.413 ? 174  ALA B CB  1 
ATOM   5418 N  N   . TYR B 1 183 ? 18.458  -21.004 6.881   1   20.357 ? 175  TYR B N   1 
ATOM   5419 C  CA  . TYR B 1 183 ? 17.649  -21.703 7.863   1   20.46  ? 175  TYR B CA  1 
ATOM   5420 C  C   . TYR B 1 183 ? 16.212  -21.769 7.356   1   21.156 ? 175  TYR B C   1 
ATOM   5421 O  O   . TYR B 1 183 ? 15.688  -20.787 6.867   1   20.492 ? 175  TYR B O   1 
ATOM   5422 C  CB  . TYR B 1 183 ? 17.718  -21.041 9.22    1   18.956 ? 175  TYR B CB  1 
ATOM   5423 C  CG  . TYR B 1 183 ? 19.044  -21.179 9.945   1   18.656 ? 175  TYR B CG  1 
ATOM   5424 C  CD1 . TYR B 1 183 ? 20.105  -20.286 9.747   1   19.305 ? 175  TYR B CD1 1 
ATOM   5425 C  CD2 . TYR B 1 183 ? 19.182  -22.166 10.902  1   18.26  ? 175  TYR B CD2 1 
ATOM   5426 C  CE1 . TYR B 1 183 ? 21.281  -20.403 10.495  1   18.263 ? 175  TYR B CE1 1 
ATOM   5427 C  CE2 . TYR B 1 183 ? 20.35   -22.315 11.642  1   18.789 ? 175  TYR B CE2 1 
ATOM   5428 C  CZ  . TYR B 1 183 ? 21.394  -21.421 11.44   1   17.984 ? 175  TYR B CZ  1 
ATOM   5429 O  OH  . TYR B 1 183 ? 22.504  -21.585 12.215  1   18.014 ? 175  TYR B OH  1 
ATOM   5430 N  N   . GLU B 1 184 ? 15.57   -22.926 7.552   1   18.317 ? 176  GLU B N   1 
ATOM   5431 C  CA  . GLU B 1 184 ? 14.174  -23.088 7.177   1   20.339 ? 176  GLU B CA  1 
ATOM   5432 C  C   . GLU B 1 184 ? 13.265  -22.741 8.351   1   21.423 ? 176  GLU B C   1 
ATOM   5433 O  O   . GLU B 1 184 ? 13.587  -23.022 9.507   1   23.133 ? 176  GLU B O   1 
ATOM   5434 C  CB  . GLU B 1 184 ? 13.901  -24.515 6.709   1   20.768 ? 176  GLU B CB  1 
ATOM   5435 C  CG  . GLU B 1 184 ? 12.447  -24.669 6.276   1   23.636 ? 176  GLU B CG  1 
ATOM   5436 C  CD  . GLU B 1 184 ? 12.082  -26.015 5.665   1   25.47  ? 176  GLU B CD  1 
ATOM   5437 O  OE1 . GLU B 1 184 ? 12.984  -26.889 5.648   1   28.362 ? 176  GLU B OE1 1 
ATOM   5438 O  OE2 . GLU B 1 184 ? 10.906  -26.143 5.267   1   25.375 ? 176  GLU B OE2 1 
ATOM   5439 N  N   . MET B 1 185 ? 12.151  -22.072 8.038   1   21.435 ? 177  MET B N   1 
ATOM   5440 C  CA  . MET B 1 185 ? 11.204  -21.736 9.083   1   19.568 ? 177  MET B CA  1 
ATOM   5441 C  C   . MET B 1 185 ? 9.819   -22.127 8.585   1   19.375 ? 177  MET B C   1 
ATOM   5442 O  O   . MET B 1 185 ? 9.572   -22.143 7.378   1   20.222 ? 177  MET B O   1 
ATOM   5443 C  CB  . MET B 1 185 ? 11.146  -20.21  9.307   1   20.037 ? 177  MET B CB  1 
ATOM   5444 C  CG  . MET B 1 185 ? 12.523  -19.605 9.67    1   23.064 ? 177  MET B CG  1 
ATOM   5445 S  SD  . MET B 1 185 ? 12.5    -17.789 9.674   1   25.349 ? 177  MET B SD  1 
ATOM   5446 C  CE  . MET B 1 185 ? 11.97   -17.501 11.364  1   22.069 ? 177  MET B CE  1 
ATOM   5447 N  N   . ASP B 1 186 ? 8.933   -22.362 9.554   1   19.704 ? 178  ASP B N   1 
ATOM   5448 C  CA  . ASP B 1 186 ? 7.529   -22.587 9.24    1   20.6   ? 178  ASP B CA  1 
ATOM   5449 C  C   . ASP B 1 186 ? 6.947   -21.264 8.743   1   22.277 ? 178  ASP B C   1 
ATOM   5450 O  O   . ASP B 1 186 ? 7.138   -20.233 9.385   1   21.304 ? 178  ASP B O   1 
ATOM   5451 C  CB  . ASP B 1 186 ? 6.81    -23.119 10.476  1   20.839 ? 178  ASP B CB  1 
ATOM   5452 C  CG  . ASP B 1 186 ? 5.346   -23.434 10.196  1   26.362 ? 178  ASP B CG  1 
ATOM   5453 O  OD1 . ASP B 1 186 ? 4.53    -22.508 10.107  1   24.04  ? 178  ASP B OD1 1 
ATOM   5454 O  OD2 . ASP B 1 186 ? 5.062   -24.611 9.924   1   27.454 ? 178  ASP B OD2 1 
ATOM   5455 N  N   . PRO B 1 187 ? 6.218   -21.212 7.603   1   21.861 ? 179  PRO B N   1 
ATOM   5456 C  CA  . PRO B 1 187 ? 5.766   -19.92  7.09    1   21.969 ? 179  PRO B CA  1 
ATOM   5457 C  C   . PRO B 1 187 ? 4.595   -19.277 7.831   1   23.125 ? 179  PRO B C   1 
ATOM   5458 O  O   . PRO B 1 187 ? 4.257   -18.12  7.555   1   23.441 ? 179  PRO B O   1 
ATOM   5459 C  CB  . PRO B 1 187 ? 5.412   -20.192 5.633   1   24.031 ? 179  PRO B CB  1 
ATOM   5460 C  CG  . PRO B 1 187 ? 5.067   -21.673 5.654   1   24.396 ? 179  PRO B CG  1 
ATOM   5461 C  CD  . PRO B 1 187 ? 5.858   -22.345 6.72    1   22.113 ? 179  PRO B CD  1 
ATOM   5462 N  N   . HIS B 1 188 ? 4.017   -20.014 8.795   1   21.648 ? 180  HIS B N   1 
ATOM   5463 C  CA  . HIS B 1 188 ? 2.851   -19.528 9.525   1   21.326 ? 180  HIS B CA  1 
ATOM   5464 C  C   . HIS B 1 188 ? 3.226   -19.202 10.965  1   21.585 ? 180  HIS B C   1 
ATOM   5465 O  O   . HIS B 1 188 ? 2.815   -18.147 11.454  1   22.567 ? 180  HIS B O   1 
ATOM   5466 C  CB  . HIS B 1 188 ? 1.762   -20.617 9.557   1   22.803 ? 180  HIS B CB  1 
ATOM   5467 C  CG  . HIS B 1 188 ? 1.587   -21.234 8.218   1   22.443 ? 180  HIS B CG  1 
ATOM   5468 N  ND1 . HIS B 1 188 ? 1.064   -20.516 7.168   1   22.667 ? 180  HIS B ND1 1 
ATOM   5469 C  CD2 . HIS B 1 188 ? 1.913   -22.456 7.737   1   22.068 ? 180  HIS B CD2 1 
ATOM   5470 C  CE1 . HIS B 1 188 ? 1.044   -21.287 6.077   1   22.33  ? 180  HIS B CE1 1 
ATOM   5471 N  NE2 . HIS B 1 188 ? 1.537   -22.486 6.413   1   23.342 ? 180  HIS B NE2 1 
ATOM   5472 N  N   . THR B 1 189 ? 3.971   -20.093 11.637  1   19.047 ? 181  THR B N   1 
ATOM   5473 C  CA  . THR B 1 189 ? 4.348   -19.876 13.022  1   19.926 ? 181  THR B CA  1 
ATOM   5474 C  C   . THR B 1 189 ? 5.72    -19.213 13.09   1   20.668 ? 181  THR B C   1 
ATOM   5475 O  O   . THR B 1 189 ? 6.113   -18.772 14.182  1   20.981 ? 181  THR B O   1 
ATOM   5476 C  CB  . THR B 1 189 ? 4.367   -21.178 13.837  1   20.894 ? 181  THR B CB  1 
ATOM   5477 O  OG1 . THR B 1 189 ? 5.461   -21.955 13.335  1   22.612 ? 181  THR B OG1 1 
ATOM   5478 C  CG2 . THR B 1 189 ? 3.023   -21.911 13.85   1   23.71  ? 181  THR B CG2 1 
ATOM   5479 N  N   . LEU B 1 190 ? 6.478   -19.259 11.979  1   19.974 ? 182  LEU B N   1 
ATOM   5480 C  CA  . LEU B 1 190 ? 7.874   -18.805 11.925  1   21.012 ? 182  LEU B CA  1 
ATOM   5481 C  C   . LEU B 1 190 ? 8.79    -19.613 12.857  1   20.381 ? 182  LEU B C   1 
ATOM   5482 O  O   . LEU B 1 190 ? 9.906   -19.178 13.133  1   21.266 ? 182  LEU B O   1 
ATOM   5483 C  CB  . LEU B 1 190 ? 8.031   -17.288 12.142  1   20.356 ? 182  LEU B CB  1 
ATOM   5484 C  CG  . LEU B 1 190 ? 7.343   -16.408 11.097  1   20.59  ? 182  LEU B CG  1 
ATOM   5485 C  CD1 . LEU B 1 190 ? 7.404   -14.885 11.46   1   20.151 ? 182  LEU B CD1 1 
ATOM   5486 C  CD2 . LEU B 1 190 ? 7.902   -16.682 9.678   1   20.912 ? 182  LEU B CD2 1 
ATOM   5487 N  N   . LYS B 1 191 ? 8.354   -20.808 13.299  1   20.391 ? 183  LYS B N   1 
ATOM   5488 C  CA  . LYS B 1 191 ? 9.239   -21.696 14.052  1   20.785 ? 183  LYS B CA  1 
ATOM   5489 C  C   . LYS B 1 191 ? 10.39   -22.127 13.13   1   19.896 ? 183  LYS B C   1 
ATOM   5490 O  O   . LYS B 1 191 ? 10.128  -22.366 11.935  1   19.938 ? 183  LYS B O   1 
ATOM   5491 C  CB  . LYS B 1 191 ? 8.413   -22.927 14.473  1   23.538 ? 183  LYS B CB  1 
ATOM   5492 C  CG  . LYS B 1 191 ? 9.183   -23.934 15.307  1   30.902 ? 183  LYS B CG  1 
ATOM   5493 C  CD  . LYS B 1 191 ? 8.321   -25.03  15.94   1   37.714 ? 183  LYS B CD  1 
ATOM   5494 C  CE  . LYS B 1 191 ? 9.131   -26.016 16.742  1   41.597 ? 183  LYS B CE  1 
ATOM   5495 N  NZ  . LYS B 1 191 ? 9.825   -25.341 17.854  1   43.49  ? 183  LYS B NZ  1 
ATOM   5496 N  N   . THR B 1 192 ? 11.619  -22.176 13.686  1   18.717 ? 184  THR B N   1 
ATOM   5497 C  CA  . THR B 1 192 ? 12.772  -22.635 12.921  1   19.361 ? 184  THR B CA  1 
ATOM   5498 C  C   . THR B 1 192 ? 12.734  -24.169 12.833  1   19.955 ? 184  THR B C   1 
ATOM   5499 O  O   . THR B 1 192 ? 12.504  -24.826 13.831  1   19.29  ? 184  THR B O   1 
ATOM   5500 C  CB  . THR B 1 192 ? 14.053  -22.132 13.567  1   19.878 ? 184  THR B CB  1 
ATOM   5501 O  OG1 . THR B 1 192 ? 13.967  -20.705 13.466  1   19.609 ? 184  THR B OG1 1 
ATOM   5502 C  CG2 . THR B 1 192 ? 15.295  -22.644 12.834  1   20.58  ? 184  THR B CG2 1 
ATOM   5503 N  N   . LEU B 1 193 ? 12.94   -24.695 11.607  1   20.968 ? 185  LEU B N   1 
ATOM   5504 C  CA  . LEU B 1 193 ? 12.774  -26.121 11.312  1   23.017 ? 185  LEU B CA  1 
ATOM   5505 C  C   . LEU B 1 193 ? 14.115  -26.82  11.064  1   23.975 ? 185  LEU B C   1 
ATOM   5506 O  O   . LEU B 1 193 ? 14.183  -28.054 11.181  1   21.634 ? 185  LEU B O   1 
ATOM   5507 C  CB  . LEU B 1 193 ? 11.867  -26.293 10.096  1   21.861 ? 185  LEU B CB  1 
ATOM   5508 C  CG  . LEU B 1 193 ? 10.462  -25.697 10.219  1   22.393 ? 185  LEU B CG  1 
ATOM   5509 C  CD1 . LEU B 1 193 ? 9.714   -26.01  8.919   1   25.88  ? 185  LEU B CD1 1 
ATOM   5510 C  CD2 . LEU B 1 193 ? 9.676   -26.201 11.485  1   22.499 ? 185  LEU B CD2 1 
ATOM   5511 N  N   . GLY B 1 194 ? 15.153  -26.075 10.654  1   21.602 ? 186  GLY B N   1 
ATOM   5512 C  CA  . GLY B 1 194 ? 16.421  -26.733 10.374  1   22.559 ? 186  GLY B CA  1 
ATOM   5513 C  C   . GLY B 1 194 ? 17.345  -25.832 9.57    1   23.125 ? 186  GLY B C   1 
ATOM   5514 O  O   . GLY B 1 194 ? 16.98   -24.681 9.303   1   23.497 ? 186  GLY B O   1 
ATOM   5515 N  N   . TYR B 1 195 ? 18.533  -26.372 9.242   1   20.036 ? 187  TYR B N   1 
ATOM   5516 C  CA  . TYR B 1 195 ? 19.56   -25.657 8.493   1   18.111 ? 187  TYR B CA  1 
ATOM   5517 C  C   . TYR B 1 195 ? 19.851  -26.4   7.212   1   19.834 ? 187  TYR B C   1 
ATOM   5518 O  O   . TYR B 1 195 ? 19.843  -27.651 7.191   1   20.725 ? 187  TYR B O   1 
ATOM   5519 C  CB  . TYR B 1 195 ? 20.783  -25.641 9.419   1   20.086 ? 187  TYR B CB  1 
ATOM   5520 C  CG  . TYR B 1 195 ? 22.014  -25.042 8.747   1   20.484 ? 187  TYR B CG  1 
ATOM   5521 C  CD1 . TYR B 1 195 ? 22.161  -23.651 8.631   1   20.748 ? 187  TYR B CD1 1 
ATOM   5522 C  CD2 . TYR B 1 195 ? 23.028  -25.857 8.252   1   20.697 ? 187  TYR B CD2 1 
ATOM   5523 C  CE1 . TYR B 1 195 ? 23.274  -23.087 8.004   1   20.255 ? 187  TYR B CE1 1 
ATOM   5524 C  CE2 . TYR B 1 195 ? 24.149  -25.317 7.637   1   20.784 ? 187  TYR B CE2 1 
ATOM   5525 C  CZ  . TYR B 1 195 ? 24.281  -23.932 7.528   1   21.14  ? 187  TYR B CZ  1 
ATOM   5526 O  OH  . TYR B 1 195 ? 25.386  -23.391 6.946   1   20.738 ? 187  TYR B OH  1 
ATOM   5527 N  N   . ASN B 1 196 ? 20.122  -25.629 6.154   1   17.784 ? 188  ASN B N   1 
ATOM   5528 C  CA  . ASN B 1 196 ? 20.557  -26.151 4.874   1   19.535 ? 188  ASN B CA  1 
ATOM   5529 C  C   . ASN B 1 196 ? 19.569  -27.192 4.347   1   20.955 ? 188  ASN B C   1 
ATOM   5530 O  O   . ASN B 1 196 ? 19.944  -28.351 4.049   1   20.862 ? 188  ASN B O   1 
ATOM   5531 C  CB  . ASN B 1 196 ? 21.986  -26.717 4.96    1   17.761 ? 188  ASN B CB  1 
ATOM   5532 C  CG  . ASN B 1 196 ? 22.592  -26.944 3.596   1   19.183 ? 188  ASN B CG  1 
ATOM   5533 O  OD1 . ASN B 1 196 ? 22.074  -26.501 2.565   1   20.054 ? 188  ASN B OD1 1 
ATOM   5534 N  ND2 . ASN B 1 196 ? 23.778  -27.553 3.583   1   20.388 ? 188  ASN B ND2 1 
ATOM   5535 N  N   . PRO B 1 197 ? 18.282  -26.805 4.175   1   20.739 ? 189  PRO B N   1 
ATOM   5536 C  CA  . PRO B 1 197 ? 17.261  -27.749 3.764   1   24.449 ? 189  PRO B CA  1 
ATOM   5537 C  C   . PRO B 1 197 ? 17.494  -28.442 2.423   1   26.096 ? 189  PRO B C   1 
ATOM   5538 O  O   . PRO B 1 197 ? 17.091  -29.601 2.246   1   24.773 ? 189  PRO B O   1 
ATOM   5539 C  CB  . PRO B 1 197 ? 15.986  -26.886 3.77    1   23.067 ? 189  PRO B CB  1 
ATOM   5540 C  CG  . PRO B 1 197 ? 16.495  -25.502 3.531   1   21.44  ? 189  PRO B CG  1 
ATOM   5541 C  CD  . PRO B 1 197 ? 17.727  -25.451 4.388   1   21.356 ? 189  PRO B CD  1 
ATOM   5542 N  N   . PHE B 1 198 ? 18.113  -27.729 1.48    1   21.267 ? 190  PHE B N   1 
ATOM   5543 C  CA  . PHE B 1 198 ? 18.472  -28.285 0.183   1   20.891 ? 190  PHE B CA  1 
ATOM   5544 C  C   . PHE B 1 198 ? 19.821  -29.026 0.164   1   23.057 ? 190  PHE B C   1 
ATOM   5545 O  O   . PHE B 1 198 ? 20.251  -29.524 -0.897  1   22.477 ? 190  PHE B O   1 
ATOM   5546 C  CB  . PHE B 1 198 ? 18.413  -27.225 -0.902  1   21.7   ? 190  PHE B CB  1 
ATOM   5547 C  CG  . PHE B 1 198 ? 17.027  -26.603 -1.037  1   20.352 ? 190  PHE B CG  1 
ATOM   5548 C  CD1 . PHE B 1 198 ? 15.901  -27.411 -1.229  1   21.605 ? 190  PHE B CD1 1 
ATOM   5549 C  CD2 . PHE B 1 198 ? 16.868  -25.216 -0.957  1   23.913 ? 190  PHE B CD2 1 
ATOM   5550 C  CE1 . PHE B 1 198 ? 14.628  -26.835 -1.358  1   21.866 ? 190  PHE B CE1 1 
ATOM   5551 C  CE2 . PHE B 1 198 ? 15.599  -24.638 -1.098  1   22.71  ? 190  PHE B CE2 1 
ATOM   5552 C  CZ  . PHE B 1 198 ? 14.488  -25.446 -1.287  1   23.147 ? 190  PHE B CZ  1 
ATOM   5553 N  N   . ASN B 1 199 ? 20.477  -29.088 1.32    1   20.421 ? 191  ASN B N   1 
ATOM   5554 C  CA  . ASN B 1 199 ? 21.691  -29.872 1.512   1   21.616 ? 191  ASN B CA  1 
ATOM   5555 C  C   . ASN B 1 199 ? 22.777  -29.443 0.528   1   22.719 ? 191  ASN B C   1 
ATOM   5556 O  O   . ASN B 1 199 ? 23.434  -30.267 -0.12   1   22.099 ? 191  ASN B O   1 
ATOM   5557 C  CB  . ASN B 1 199 ? 21.358  -31.368 1.489   1   25.81  ? 191  ASN B CB  1 
ATOM   5558 C  CG  . ASN B 1 199 ? 22.508  -32.238 1.926   1   32.719 ? 191  ASN B CG  1 
ATOM   5559 O  OD1 . ASN B 1 199 ? 23.178  -31.955 2.935   1   33.255 ? 191  ASN B OD1 1 
ATOM   5560 N  ND2 . ASN B 1 199 ? 22.747  -33.313 1.189   1   35.95  ? 191  ASN B ND2 1 
ATOM   5561 N  N   . LEU B 1 200 ? 22.936  -28.133 0.346   1   21.598 ? 192  LEU B N   1 
ATOM   5562 C  CA  . LEU B 1 200 ? 24.008  -27.664 -0.519  1   20.117 ? 192  LEU B CA  1 
ATOM   5563 C  C   . LEU B 1 200 ? 25.372  -28.078 0.043   1   18.401 ? 192  LEU B C   1 
ATOM   5564 O  O   . LEU B 1 200 ? 25.58   -28.093 1.277   1   19.03  ? 192  LEU B O   1 
ATOM   5565 C  CB  . LEU B 1 200 ? 23.928  -26.159 -0.751  1   21.253 ? 192  LEU B CB  1 
ATOM   5566 C  CG  . LEU B 1 200 ? 22.592  -25.672 -1.32   1   21.237 ? 192  LEU B CG  1 
ATOM   5567 C  CD1 . LEU B 1 200 ? 22.75   -24.182 -1.592  1   22.209 ? 192  LEU B CD1 1 
ATOM   5568 C  CD2 . LEU B 1 200 ? 22.174  -26.426 -2.592  1   22.895 ? 192  LEU B CD2 1 
ATOM   5569 N  N   . PRO B 1 201 ? 26.328  -28.443 -0.849  1   19.46  ? 193  PRO B N   1 
ATOM   5570 C  CA  . PRO B 1 201 ? 27.66   -28.863 -0.407  1   18.601 ? 193  PRO B CA  1 
ATOM   5571 C  C   . PRO B 1 201 ? 28.573  -27.708 -0.023  1   19.728 ? 193  PRO B C   1 
ATOM   5572 O  O   . PRO B 1 201 ? 29.641  -27.915 0.568   1   21.409 ? 193  PRO B O   1 
ATOM   5573 C  CB  . PRO B 1 201 ? 28.198  -29.624 -1.628  1   20.569 ? 193  PRO B CB  1 
ATOM   5574 C  CG  . PRO B 1 201 ? 27.539  -28.929 -2.807  1   20.625 ? 193  PRO B CG  1 
ATOM   5575 C  CD  . PRO B 1 201 ? 26.135  -28.574 -2.311  1   19.151 ? 193  PRO B CD  1 
ATOM   5576 N  N   . SER B 1 202 ? 28.235  -26.474 -0.454  1   19.238 ? 194  SER B N   1 
ATOM   5577 C  CA  . SER B 1 202 ? 29.015  -25.303 -0.048  1   20.132 ? 194  SER B CA  1 
ATOM   5578 C  C   . SER B 1 202 ? 28.744  -24.979 1.428   1   17.873 ? 194  SER B C   1 
ATOM   5579 O  O   . SER B 1 202 ? 27.748  -25.411 2.006   1   19.898 ? 194  SER B O   1 
ATOM   5580 C  CB  . SER B 1 202 ? 28.658  -24.101 -0.879  1   22.196 ? 194  SER B CB  1 
ATOM   5581 O  OG  . SER B 1 202 ? 27.239  -24.054 -0.899  1   24.722 ? 194  SER B OG  1 
ATOM   5582 N  N   . LYS B 1 203 ? 29.65   -24.207 2.051   1   21.326 ? 195  LYS B N   1 
ATOM   5583 C  CA  . LYS B 1 203 ? 29.415  -23.776 3.425   1   19.08  ? 195  LYS B CA  1 
ATOM   5584 C  C   . LYS B 1 203 ? 28.492  -22.549 3.433   1   19.908 ? 195  LYS B C   1 
ATOM   5585 O  O   . LYS B 1 203 ? 28.03   -22.142 4.524   1   20.237 ? 195  LYS B O   1 
ATOM   5586 C  CB  . LYS B 1 203 ? 30.741  -23.418 4.093   1   20.474 ? 195  LYS B CB  1 
ATOM   5587 C  CG  . LYS B 1 203 ? 31.655  -24.597 4.263   1   23.095 ? 195  LYS B CG  1 
ATOM   5588 C  CD  . LYS B 1 203 ? 32.878  -24.115 5.013   1   27.715 ? 195  LYS B CD  1 
ATOM   5589 C  CE  . LYS B 1 203 ? 33.887  -25.217 5.073   1   28.531 ? 195  LYS B CE  1 
ATOM   5590 N  NZ  . LYS B 1 203 ? 33.934  -25.873 6.362   1   37.597 ? 195  LYS B NZ  1 
ATOM   5591 N  N   . THR B 1 204 ? 28.223  -21.99  2.251   1   17.787 ? 196  THR B N   1 
ATOM   5592 C  CA  . THR B 1 204 ? 27.449  -20.736 2.17    1   17.099 ? 196  THR B CA  1 
ATOM   5593 C  C   . THR B 1 204 ? 26.413  -20.825 1.068   1   21.721 ? 196  THR B C   1 
ATOM   5594 O  O   . THR B 1 204 ? 26.542  -21.609 0.107   1   20.378 ? 196  THR B O   1 
ATOM   5595 C  CB  . THR B 1 204 ? 28.416  -19.578 1.842   1   19.374 ? 196  THR B CB  1 
ATOM   5596 O  OG1 . THR B 1 204 ? 29.005  -19.845 0.559   1   19.918 ? 196  THR B OG1 1 
ATOM   5597 C  CG2 . THR B 1 204 ? 29.474  -19.377 2.921   1   18.846 ? 196  THR B CG2 1 
ATOM   5598 N  N   . MET B 1 205 ? 25.39   -19.958 1.191   1   19.529 ? 197  MET B N   1 
ATOM   5599 C  CA  . MET B 1 205 ? 24.519  -19.68  0.08    1   17.686 ? 197  MET B CA  1 
ATOM   5600 C  C   . MET B 1 205 ? 24.256  -18.172 0.103   1   18.397 ? 197  MET B C   1 
ATOM   5601 O  O   . MET B 1 205 ? 24.017  -17.593 1.165   1   19.297 ? 197  MET B O   1 
ATOM   5602 C  CB  . MET B 1 205 ? 23.18   -20.446 0.2     1   17.61  ? 197  MET B CB  1 
ATOM   5603 C  CG  . MET B 1 205 ? 22.321  -20.283 -1.065  1   19.342 ? 197  MET B CG  1 
ATOM   5604 S  SD  . MET B 1 205 ? 20.68   -21.021 -0.851  1   21.359 ? 197  MET B SD  1 
ATOM   5605 C  CE  . MET B 1 205 ? 19.905  -19.707 0.11    1   20.439 ? 197  MET B CE  1 
ATOM   5606 N  N   . THR B 1 206 ? 24.268  -17.566 -1.094  1   16.839 ? 198  THR B N   1 
ATOM   5607 C  CA  . THR B 1 206 ? 23.816  -16.194 -1.278  1   17.105 ? 198  THR B CA  1 
ATOM   5608 C  C   . THR B 1 206 ? 22.461  -15.952 -0.617  1   17.986 ? 198  THR B C   1 
ATOM   5609 O  O   . THR B 1 206 ? 21.591  -16.838 -0.549  1   17.767 ? 198  THR B O   1 
ATOM   5610 C  CB  . THR B 1 206 ? 23.78   -15.924 -2.789  1   17.719 ? 198  THR B CB  1 
ATOM   5611 O  OG1 . THR B 1 206 ? 23.518  -14.525 -2.928  1   19.847 ? 198  THR B OG1 1 
ATOM   5612 C  CG2 . THR B 1 206 ? 22.645  -16.639 -3.517  1   17.767 ? 198  THR B CG2 1 
ATOM   5613 N  N   . ALA B 1 207 ? 22.278  -14.708 -0.153  1   19.378 ? 199  ALA B N   1 
ATOM   5614 C  CA  . ALA B 1 207 ? 20.959  -14.273 0.281   1   18.719 ? 199  ALA B CA  1 
ATOM   5615 C  C   . ALA B 1 207 ? 20.202  -13.649 -0.878  1   20.049 ? 199  ALA B C   1 
ATOM   5616 O  O   . ALA B 1 207 ? 19.08   -13.221 -0.674  1   21.387 ? 199  ALA B O   1 
ATOM   5617 C  CB  . ALA B 1 207 ? 21.078  -13.314 1.462   1   20.612 ? 199  ALA B CB  1 
ATOM   5618 N  N   . HIS B 1 208 ? 20.779  -13.73  -2.1    1   18.415 ? 200  HIS B N   1 
ATOM   5619 C  CA  . HIS B 1 208 ? 20.121  -13.221 -3.301  1   19.887 ? 200  HIS B CA  1 
ATOM   5620 C  C   . HIS B 1 208 ? 19.983  -14.288 -4.386  1   19.064 ? 200  HIS B C   1 
ATOM   5621 O  O   . HIS B 1 208 ? 20.316  -14.021 -5.549  1   19.311 ? 200  HIS B O   1 
ATOM   5622 C  CB  . HIS B 1 208 ? 20.835  -11.954 -3.809  1   19.99  ? 200  HIS B CB  1 
ATOM   5623 C  CG  . HIS B 1 208 ? 20.484  -10.771 -2.982  1   19.859 ? 200  HIS B CG  1 
ATOM   5624 N  ND1 . HIS B 1 208 ? 19.21   -10.241 -3.008  1   18.126 ? 200  HIS B ND1 1 
ATOM   5625 C  CD2 . HIS B 1 208 ? 21.193  -10.063 -2.053  1   19.113 ? 200  HIS B CD2 1 
ATOM   5626 C  CE1 . HIS B 1 208 ? 19.139  -9.243  -2.127  1   18.951 ? 200  HIS B CE1 1 
ATOM   5627 N  NE2 . HIS B 1 208 ? 20.355  -9.106  -1.551  1   18.251 ? 200  HIS B NE2 1 
ATOM   5628 N  N   . PRO B 1 209 ? 19.431  -15.492 -4.094  1   19.784 ? 201  PRO B N   1 
ATOM   5629 C  CA  . PRO B 1 209 ? 19.105  -16.423 -5.168  1   20.652 ? 201  PRO B CA  1 
ATOM   5630 C  C   . PRO B 1 209 ? 17.921  -15.9   -5.975  1   21.393 ? 201  PRO B C   1 
ATOM   5631 O  O   . PRO B 1 209 ? 17.142  -15.094 -5.473  1   21.205 ? 201  PRO B O   1 
ATOM   5632 C  CB  . PRO B 1 209 ? 18.733  -17.701 -4.414  1   20.079 ? 201  PRO B CB  1 
ATOM   5633 C  CG  . PRO B 1 209 ? 18.067  -17.15  -3.144  1   19.135 ? 201  PRO B CG  1 
ATOM   5634 C  CD  . PRO B 1 209 ? 18.949  -15.987 -2.772  1   18.767 ? 201  PRO B CD  1 
ATOM   5635 N  N   . LYS B 1 210 ? 17.854  -16.329 -7.227  1   18.113 ? 202  LYS B N   1 
ATOM   5636 C  CA  . LYS B 1 210 ? 16.823  -15.802 -8.11   1   20.432 ? 202  LYS B CA  1 
ATOM   5637 C  C   . LYS B 1 210 ? 15.941  -16.957 -8.572  1   19.909 ? 202  LYS B C   1 
ATOM   5638 O  O   . LYS B 1 210 ? 16.468  -18.003 -8.975  1   23.77  ? 202  LYS B O   1 
ATOM   5639 C  CB  . LYS B 1 210 ? 17.465  -15.097 -9.319  1   18.489 ? 202  LYS B CB  1 
ATOM   5640 C  CG  . LYS B 1 210 ? 18.553  -14.036 -9.018  1   20.377 ? 202  LYS B CG  1 
ATOM   5641 C  CD  . LYS B 1 210 ? 18.061  -12.789 -8.26   1   22.314 ? 202  LYS B CD  1 
ATOM   5642 C  CE  . LYS B 1 210 ? 19.245  -11.96  -7.772  1   20.748 ? 202  LYS B CE  1 
ATOM   5643 N  NZ  . LYS B 1 210 ? 18.835  -10.765 -7.012  1   20.954 ? 202  LYS B NZ  1 
ATOM   5644 N  N   . GLN B 1 211 ? 14.611  -16.755 -8.467  1   20.024 ? 203  GLN B N   1 
ATOM   5645 C  CA  . GLN B 1 211 ? 13.697  -17.823 -8.829  1   20.714 ? 203  GLN B CA  1 
ATOM   5646 C  C   . GLN B 1 211 ? 13.288  -17.604 -10.282 1   22.512 ? 203  GLN B C   1 
ATOM   5647 O  O   . GLN B 1 211 ? 12.516  -16.695 -10.578 1   23.564 ? 203  GLN B O   1 
ATOM   5648 C  CB  . GLN B 1 211 ? 12.502  -17.793 -7.884  1   25.85  ? 203  GLN B CB  1 
ATOM   5649 C  CG  . GLN B 1 211 ? 12.785  -18.477 -6.558  1   33.923 ? 203  GLN B CG  1 
ATOM   5650 C  CD  . GLN B 1 211 ? 11.491  -18.701 -5.801  1   38.213 ? 203  GLN B CD  1 
ATOM   5651 O  OE1 . GLN B 1 211 ? 10.827  -17.731 -5.416  1   43.867 ? 203  GLN B OE1 1 
ATOM   5652 N  NE2 . GLN B 1 211 ? 11.078  -19.957 -5.658  1   29.773 ? 203  GLN B NE2 1 
ATOM   5653 N  N   . CYS B 1 212 ? 13.839  -18.447 -11.142 1   22.164 ? 204  CYS B N   1 
ATOM   5654 C  CA  . CYS B 1 212 ? 13.686  -18.389 -12.588 1   22.109 ? 204  CYS B CA  1 
ATOM   5655 C  C   . CYS B 1 212 ? 12.205  -18.552 -12.959 1   22.497 ? 204  CYS B C   1 
ATOM   5656 O  O   . CYS B 1 212 ? 11.598  -19.547 -12.599 1   25.9   ? 204  CYS B O   1 
ATOM   5657 C  CB  . CYS B 1 212 ? 14.478  -19.539 -13.199 1   22.486 ? 204  CYS B CB  1 
ATOM   5658 S  SG  . CYS B 1 212 ? 14.377  -19.59  -15.027 1   25.525 ? 204  CYS B SG  1 
ATOM   5659 N  N   . SER B 1 213 ? 11.659  -17.58  -13.708 1   24.822 ? 205  SER B N   1 
ATOM   5660 C  CA  . SER B 1 213 ? 10.257  -17.62  -14.1   1   28.97  ? 205  SER B CA  1 
ATOM   5661 C  C   . SER B 1 213 ? 10.017  -18.643 -15.222 1   30.535 ? 205  SER B C   1 
ATOM   5662 O  O   . SER B 1 213 ? 8.864   -18.98  -15.48  1   30.158 ? 205  SER B O   1 
ATOM   5663 C  CB  . SER B 1 213 ? 9.767   -16.231 -14.47  1   29.018 ? 205  SER B CB  1 
ATOM   5664 O  OG  . SER B 1 213 ? 10.364  -15.782 -15.694 1   33.542 ? 205  SER B OG  1 
ATOM   5665 N  N   . VAL B 1 214 ? 11.089  -19.142 -15.862 1   27.289 ? 206  VAL B N   1 
ATOM   5666 C  CA  . VAL B 1 214 ? 10.964  -20.089 -16.965 1   29.985 ? 206  VAL B CA  1 
ATOM   5667 C  C   . VAL B 1 214 ? 10.96   -21.527 -16.444 1   30.183 ? 206  VAL B C   1 
ATOM   5668 O  O   . VAL B 1 214 ? 10.04   -22.279 -16.734 1   31.735 ? 206  VAL B O   1 
ATOM   5669 C  CB  . VAL B 1 214 ? 11.984  -19.862 -18.102 1   29.54  ? 206  VAL B CB  1 
ATOM   5670 C  CG1 . VAL B 1 214 ? 11.914  -20.964 -19.163 1   29.015 ? 206  VAL B CG1 1 
ATOM   5671 C  CG2 . VAL B 1 214 ? 11.74   -18.5   -18.745 1   30.764 ? 206  VAL B CG2 1 
ATOM   5672 N  N   . THR B 1 215 ? 11.96   -21.896 -15.642 1   27.22  ? 207  THR B N   1 
ATOM   5673 C  CA  . THR B 1 215 ? 12.165  -23.253 -15.179 1   23.91  ? 207  THR B CA  1 
ATOM   5674 C  C   . THR B 1 215 ? 11.592  -23.428 -13.777 1   23.504 ? 207  THR B C   1 
ATOM   5675 O  O   . THR B 1 215 ? 11.389  -24.569 -13.34  1   24.539 ? 207  THR B O   1 
ATOM   5676 C  CB  . THR B 1 215 ? 13.678  -23.565 -15.171 1   23.684 ? 207  THR B CB  1 
ATOM   5677 O  OG1 . THR B 1 215 ? 14.284  -22.711 -14.192 1   24.019 ? 207  THR B OG1 1 
ATOM   5678 C  CG2 . THR B 1 215 ? 14.275  -23.549 -16.569 1   25.907 ? 207  THR B CG2 1 
ATOM   5679 N  N   . GLY B 1 216 ? 11.426  -22.308 -13.046 1   23.64  ? 208  GLY B N   1 
ATOM   5680 C  CA  . GLY B 1 216 ? 11.041  -22.429 -11.637 1   25.154 ? 208  GLY B CA  1 
ATOM   5681 C  C   . GLY B 1 216 ? 12.238  -22.737 -10.737 1   24.954 ? 208  GLY B C   1 
ATOM   5682 O  O   . GLY B 1 216 ? 12.085  -22.876 -9.516  1   25.031 ? 208  GLY B O   1 
ATOM   5683 N  N   . ASN B 1 217 ? 13.431  -22.842 -11.333 1   23.768 ? 209  ASN B N   1 
ATOM   5684 C  CA  . ASN B 1 217 ? 14.639  -23.135 -10.555 1   24.606 ? 209  ASN B CA  1 
ATOM   5685 C  C   . ASN B 1 217 ? 15.023  -21.965 -9.649  1   21.604 ? 209  ASN B C   1 
ATOM   5686 O  O   . ASN B 1 217 ? 14.87   -20.817 -10.037 1   22.171 ? 209  ASN B O   1 
ATOM   5687 C  CB  . ASN B 1 217 ? 15.863  -23.427 -11.432 1   22.724 ? 209  ASN B CB  1 
ATOM   5688 C  CG  . ASN B 1 217 ? 15.759  -24.733 -12.198 1   23.191 ? 209  ASN B CG  1 
ATOM   5689 O  OD1 . ASN B 1 217 ? 14.822  -25.529 -12.015 1   24.551 ? 209  ASN B OD1 1 
ATOM   5690 N  ND2 . ASN B 1 217 ? 16.685  -24.936 -13.114 1   24.244 ? 209  ASN B ND2 1 
ATOM   5691 N  N   . LEU B 1 218 ? 15.495  -22.304 -8.431  1   20.796 ? 210  LEU B N   1 
ATOM   5692 C  CA  . LEU B 1 218 ? 16.179  -21.352 -7.574  1   18.711 ? 210  LEU B CA  1 
ATOM   5693 C  C   . LEU B 1 218 ? 17.628  -21.352 -8.023  1   19.497 ? 210  LEU B C   1 
ATOM   5694 O  O   . LEU B 1 218 ? 18.351  -22.321 -7.76   1   22.02  ? 210  LEU B O   1 
ATOM   5695 C  CB  . LEU B 1 218 ? 16.027  -21.767 -6.102  1   19.128 ? 210  LEU B CB  1 
ATOM   5696 C  CG  . LEU B 1 218 ? 16.552  -20.801 -5.029  1   23.106 ? 210  LEU B CG  1 
ATOM   5697 C  CD1 . LEU B 1 218 ? 15.755  -19.524 -4.977  1   22.938 ? 210  LEU B CD1 1 
ATOM   5698 C  CD2 . LEU B 1 218 ? 16.583  -21.398 -3.617  1   27.958 ? 210  LEU B CD2 1 
ATOM   5699 N  N   . VAL B 1 219 ? 18.054  -20.213 -8.585  1   19.666 ? 211  VAL B N   1 
ATOM   5700 C  CA  . VAL B 1 219 ? 19.379  -20.1   -9.179  1   20.899 ? 211  VAL B CA  1 
ATOM   5701 C  C   . VAL B 1 219 ? 20.236  -19.236 -8.284  1   20.457 ? 211  VAL B C   1 
ATOM   5702 O  O   . VAL B 1 219 ? 19.843  -18.133 -7.939  1   22.22  ? 211  VAL B O   1 
ATOM   5703 C  CB  . VAL B 1 219 ? 19.31   -19.523 -10.593 1   21.941 ? 211  VAL B CB  1 
ATOM   5704 C  CG1 . VAL B 1 219 ? 20.687  -19.486 -11.222 1   21.362 ? 211  VAL B CG1 1 
ATOM   5705 C  CG2 . VAL B 1 219 ? 18.321  -20.308 -11.464 1   21.513 ? 211  VAL B CG2 1 
ATOM   5706 N  N   . GLY B 1 220 ? 21.368  -19.791 -7.857  1   22.59  ? 212  GLY B N   1 
ATOM   5707 C  CA  . GLY B 1 220 ? 22.208  -18.967 -7.008  1   19.753 ? 212  GLY B CA  1 
ATOM   5708 C  C   . GLY B 1 220 ? 23.63   -19.491 -6.947  1   20.959 ? 212  GLY B C   1 
ATOM   5709 O  O   . GLY B 1 220 ? 24.091  -20.179 -7.843  1   19.828 ? 212  GLY B O   1 
ATOM   5710 N  N   . PHE B 1 221 ? 24.288  -19.125 -5.848  1   20.169 ? 213  PHE B N   1 
ATOM   5711 C  CA  . PHE B 1 221 ? 25.704  -19.373 -5.677  1   19.533 ? 213  PHE B CA  1 
ATOM   5712 C  C   . PHE B 1 221 ? 25.994  -19.227 -4.181  1   19.647 ? 213  PHE B C   1 
ATOM   5713 O  O   . PHE B 1 221 ? 25.173  -18.696 -3.424  1   21.391 ? 213  PHE B O   1 
ATOM   5714 C  CB  . PHE B 1 221 ? 26.586  -18.41  -6.481  1   19.924 ? 213  PHE B CB  1 
ATOM   5715 C  CG  . PHE B 1 221 ? 26.471  -16.961 -6.023  1   20.497 ? 213  PHE B CG  1 
ATOM   5716 C  CD1 . PHE B 1 221 ? 25.336  -16.199 -6.356  1   20.377 ? 213  PHE B CD1 1 
ATOM   5717 C  CD2 . PHE B 1 221 ? 27.456  -16.399 -5.214  1   18.595 ? 213  PHE B CD2 1 
ATOM   5718 C  CE1 . PHE B 1 221 ? 25.211  -14.887 -5.908  1   20.578 ? 213  PHE B CE1 1 
ATOM   5719 C  CE2 . PHE B 1 221 ? 27.325  -15.099 -4.756  1   20.909 ? 213  PHE B CE2 1 
ATOM   5720 C  CZ  . PHE B 1 221 ? 26.207  -14.335 -5.101  1   20.328 ? 213  PHE B CZ  1 
ATOM   5721 N  N   . GLY B 1 222 ? 27.171  -19.679 -3.774  1   20.212 ? 214  GLY B N   1 
ATOM   5722 C  CA  . GLY B 1 222 ? 27.702  -19.277 -2.476  1   19.734 ? 214  GLY B CA  1 
ATOM   5723 C  C   . GLY B 1 222 ? 29.172  -18.94  -2.677  1   20.26  ? 214  GLY B C   1 
ATOM   5724 O  O   . GLY B 1 222 ? 29.843  -19.638 -3.441  1   21.911 ? 214  GLY B O   1 
ATOM   5725 N  N   . TYR B 1 223 ? 29.637  -17.834 -2.087  1   19.067 ? 215  TYR B N   1 
ATOM   5726 C  CA  . TYR B 1 223 ? 31.051  -17.485 -2.206  1   21.616 ? 215  TYR B CA  1 
ATOM   5727 C  C   . TYR B 1 223 ? 31.677  -17.7   -0.836  1   20.116 ? 215  TYR B C   1 
ATOM   5728 O  O   . TYR B 1 223 ? 30.937  -17.971 0.132   1   20.507 ? 215  TYR B O   1 
ATOM   5729 C  CB  . TYR B 1 223 ? 31.214  -16.074 -2.822  1   21.271 ? 215  TYR B CB  1 
ATOM   5730 C  CG  . TYR B 1 223 ? 30.905  -14.963 -1.83   1   19.522 ? 215  TYR B CG  1 
ATOM   5731 C  CD1 . TYR B 1 223 ? 29.584  -14.52  -1.657  1   20.358 ? 215  TYR B CD1 1 
ATOM   5732 C  CD2 . TYR B 1 223 ? 31.927  -14.378 -1.064  1   18.524 ? 215  TYR B CD2 1 
ATOM   5733 C  CE1 . TYR B 1 223 ? 29.279  -13.555 -0.711  1   20.215 ? 215  TYR B CE1 1 
ATOM   5734 C  CE2 . TYR B 1 223 ? 31.625  -13.429 -0.102  1   19.917 ? 215  TYR B CE2 1 
ATOM   5735 C  CZ  . TYR B 1 223 ? 30.315  -12.999 0.043   1   20.202 ? 215  TYR B CZ  1 
ATOM   5736 O  OH  . TYR B 1 223 ? 30.06   -12.038 0.969   1   21.987 ? 215  TYR B OH  1 
ATOM   5737 N  N   . GLU B 1 224 ? 33.04   -17.627 -0.767  1   18.563 ? 216  GLU B N   1 
ATOM   5738 C  CA  . GLU B 1 224 ? 33.735  -18.227 0.376   1   19.101 ? 216  GLU B CA  1 
ATOM   5739 C  C   . GLU B 1 224 ? 33.195  -19.631 0.662   1   18.515 ? 216  GLU B C   1 
ATOM   5740 O  O   . GLU B 1 224 ? 32.976  -20.014 1.827   1   20.39  ? 216  GLU B O   1 
ATOM   5741 C  CB  . GLU B 1 224 ? 33.678  -17.379 1.647   1   18.196 ? 216  GLU B CB  1 
ATOM   5742 C  CG  . GLU B 1 224 ? 34.399  -16.057 1.388   1   19.634 ? 216  GLU B CG  1 
ATOM   5743 C  CD  . GLU B 1 224 ? 34.697  -15.169 2.557   1   19.781 ? 216  GLU B CD  1 
ATOM   5744 O  OE1 . GLU B 1 224 ? 34.969  -15.69  3.638   1   19.765 ? 216  GLU B OE1 1 
ATOM   5745 O  OE2 . GLU B 1 224 ? 34.634  -13.93  2.398   1   23.157 ? 216  GLU B OE2 1 
ATOM   5746 N  N   . ALA B 1 225 ? 32.975  -20.367 -0.426  1   21.229 ? 217  ALA B N   1 
ATOM   5747 C  CA  . ALA B 1 225 ? 32.194  -21.6   -0.355  1   20.565 ? 217  ALA B CA  1 
ATOM   5748 C  C   . ALA B 1 225 ? 32.928  -22.703 0.401   1   21.48  ? 217  ALA B C   1 
ATOM   5749 O  O   . ALA B 1 225 ? 32.284  -23.653 0.834   1   21.132 ? 217  ALA B O   1 
ATOM   5750 C  CB  . ALA B 1 225 ? 31.803  -22.023 -1.755  1   20.577 ? 217  ALA B CB  1 
ATOM   5751 N  N   . LYS B 1 226 ? 34.252  -22.561 0.606   1   21.409 ? 218  LYS B N   1 
ATOM   5752 C  CA  . LYS B 1 226 ? 35.025  -23.586 1.306   1   20.903 ? 218  LYS B CA  1 
ATOM   5753 C  C   . LYS B 1 226 ? 35.541  -23.04  2.628   1   21.697 ? 218  LYS B C   1 
ATOM   5754 O  O   . LYS B 1 226 ? 36.369  -23.688 3.273   1   22.9   ? 218  LYS B O   1 
ATOM   5755 C  CB  . LYS B 1 226 ? 36.204  -24.102 0.453   1   20.245 ? 218  LYS B CB  1 
ATOM   5756 C  CG  . LYS B 1 226 ? 35.702  -24.841 -0.784  1   23.282 ? 218  LYS B CG  1 
ATOM   5757 C  CD  . LYS B 1 226 ? 36.782  -25.666 -1.506  1   24.37  ? 218  LYS B CD  1 
ATOM   5758 C  CE  . LYS B 1 226 ? 36.19   -26.247 -2.792  1   27.511 ? 218  LYS B CE  1 
ATOM   5759 N  NZ  . LYS B 1 226 ? 36.921  -27.442 -3.294  1   26.611 ? 218  LYS B NZ  1 
ATOM   5760 N  N   . GLY B 1 227 ? 35.039  -21.883 3.075   1   19.967 ? 219  GLY B N   1 
ATOM   5761 C  CA  . GLY B 1 227 ? 35.448  -21.406 4.399   1   20.925 ? 219  GLY B CA  1 
ATOM   5762 C  C   . GLY B 1 227 ? 35.978  -19.982 4.345   1   19.52  ? 219  GLY B C   1 
ATOM   5763 O  O   . GLY B 1 227 ? 36.054  -19.361 3.277   1   20.249 ? 219  GLY B O   1 
ATOM   5764 N  N   . LEU B 1 228 ? 36.357  -19.457 5.524   1   19.384 ? 220  LEU B N   1 
ATOM   5765 C  CA  . LEU B 1 228 ? 36.859  -18.093 5.65    1   21.197 ? 220  LEU B CA  1 
ATOM   5766 C  C   . LEU B 1 228 ? 37.959  -17.755 4.64    1   23.356 ? 220  LEU B C   1 
ATOM   5767 O  O   . LEU B 1 228 ? 38.99   -18.408 4.566   1   22.201 ? 220  LEU B O   1 
ATOM   5768 C  CB  . LEU B 1 228 ? 37.431  -18.031 7.064   1   24.983 ? 220  LEU B CB  1 
ATOM   5769 C  CG  . LEU B 1 228 ? 36.966  -16.943 8.026   1   32.035 ? 220  LEU B CG  1 
ATOM   5770 C  CD1 . LEU B 1 228 ? 35.514  -16.455 8.06    1   19.419 ? 220  LEU B CD1 1 
ATOM   5771 C  CD2 . LEU B 1 228 ? 37.409  -17.445 9.426   1   25.666 ? 220  LEU B CD2 1 
ATOM   5772 N  N   . ALA B 1 229 ? 37.71   -16.669 3.899   1   21.784 ? 221  ALA B N   1 
ATOM   5773 C  CA  . ALA B 1 229 ? 38.594  -16.031 2.943   1   25.026 ? 221  ALA B CA  1 
ATOM   5774 C  C   . ALA B 1 229 ? 38.872  -16.91  1.72    1   22.937 ? 221  ALA B C   1 
ATOM   5775 O  O   . ALA B 1 229 ? 39.766  -16.542 0.952   1   24.317 ? 221  ALA B O   1 
ATOM   5776 C  CB  . ALA B 1 229 ? 39.889  -15.5   3.605   1   22.545 ? 221  ALA B CB  1 
ATOM   5777 N  N   . THR B 1 230 ? 38.067  -17.962 1.461   1   20.966 ? 222  THR B N   1 
ATOM   5778 C  CA  . THR B 1 230 ? 38.345  -18.809 0.303   1   20.506 ? 222  THR B CA  1 
ATOM   5779 C  C   . THR B 1 230 ? 37.818  -18.108 -0.947  1   21.952 ? 222  THR B C   1 
ATOM   5780 O  O   . THR B 1 230 ? 36.781  -17.43  -0.899  1   20.284 ? 222  THR B O   1 
ATOM   5781 C  CB  . THR B 1 230 ? 37.8    -20.234 0.446   1   23.386 ? 222  THR B CB  1 
ATOM   5782 O  OG1 . THR B 1 230 ? 36.384  -20.179 0.664   1   20.106 ? 222  THR B OG1 1 
ATOM   5783 C  CG2 . THR B 1 230 ? 38.526  -21.004 1.537   1   19.934 ? 222  THR B CG2 1 
ATOM   5784 N  N   . LYS B 1 231 ? 38.529  -18.29  -2.066  1   20.551 ? 223  LYS B N   1 
ATOM   5785 C  CA  . LYS B 1 231 ? 38.088  -17.724 -3.339  1   23.694 ? 223  LYS B CA  1 
ATOM   5786 C  C   . LYS B 1 231 ? 37.025  -18.576 -4.033  1   20.747 ? 223  LYS B C   1 
ATOM   5787 O  O   . LYS B 1 231 ? 36.46   -18.148 -5.036  1   21.597 ? 223  LYS B O   1 
ATOM   5788 C  CB  . LYS B 1 231 ? 39.304  -17.585 -4.27   1   21.027 ? 223  LYS B CB  1 
ATOM   5789 C  CG  . LYS B 1 231 ? 40.198  -16.446 -3.778  1   22.279 ? 223  LYS B CG  1 
ATOM   5790 C  CD  . LYS B 1 231 ? 41.257  -16.071 -4.827  1   28.126 ? 223  LYS B CD  1 
ATOM   5791 C  CE  . LYS B 1 231 ? 42.305  -17.111 -5.019  1   38.088 ? 223  LYS B CE  1 
ATOM   5792 N  NZ  . LYS B 1 231 ? 43.177  -16.825 -6.167  1   47.467 ? 223  LYS B NZ  1 
ATOM   5793 N  N   . ASP B 1 232 ? 36.767  -19.783 -3.514  1   19.767 ? 224  ASP B N   1 
ATOM   5794 C  CA  . ASP B 1 232 ? 35.813  -20.7   -4.122  1   20.116 ? 224  ASP B CA  1 
ATOM   5795 C  C   . ASP B 1 232 ? 34.387  -20.143 -4.175  1   20.247 ? 224  ASP B C   1 
ATOM   5796 O  O   . ASP B 1 232 ? 33.856  -19.578 -3.21   1   20.081 ? 224  ASP B O   1 
ATOM   5797 C  CB  . ASP B 1 232 ? 35.789  -22.034 -3.392  1   22.305 ? 224  ASP B CB  1 
ATOM   5798 C  CG  . ASP B 1 232 ? 37.203  -22.614 -3.312  1   23.967 ? 224  ASP B CG  1 
ATOM   5799 O  OD1 . ASP B 1 232 ? 37.929  -22.273 -2.369  1   24.578 ? 224  ASP B OD1 1 
ATOM   5800 O  OD2 . ASP B 1 232 ? 37.61   -23.304 -4.259  1   24.531 ? 224  ASP B OD2 1 
ATOM   5801 N  N   . VAL B 1 233 ? 33.779  -20.344 -5.345  1   19.288 ? 225  VAL B N   1 
ATOM   5802 C  CA  . VAL B 1 233 ? 32.366  -20.032 -5.549  1   19.953 ? 225  VAL B CA  1 
ATOM   5803 C  C   . VAL B 1 233 ? 31.676  -21.297 -6.055  1   21.016 ? 225  VAL B C   1 
ATOM   5804 O  O   . VAL B 1 233 ? 32.176  -21.946 -6.981  1   21.094 ? 225  VAL B O   1 
ATOM   5805 C  CB  . VAL B 1 233 ? 32.241  -18.856 -6.539  1   20.752 ? 225  VAL B CB  1 
ATOM   5806 C  CG1 . VAL B 1 233 ? 30.748  -18.558 -6.835  1   23.777 ? 225  VAL B CG1 1 
ATOM   5807 C  CG2 . VAL B 1 233 ? 32.939  -17.602 -5.984  1   18.987 ? 225  VAL B CG2 1 
ATOM   5808 N  N   . TYR B 1 234 ? 30.506  -21.6   -5.457  1   19.449 ? 226  TYR B N   1 
ATOM   5809 C  CA  . TYR B 1 234 ? 29.691  -22.725 -5.881  1   19.803 ? 226  TYR B CA  1 
ATOM   5810 C  C   . TYR B 1 234 ? 28.412  -22.17  -6.517  1   19.937 ? 226  TYR B C   1 
ATOM   5811 O  O   . TYR B 1 234 ? 27.656  -21.49  -5.852  1   21.935 ? 226  TYR B O   1 
ATOM   5812 C  CB  . TYR B 1 234 ? 29.317  -23.558 -4.646  1   18.135 ? 226  TYR B CB  1 
ATOM   5813 C  CG  . TYR B 1 234 ? 28.371  -24.718 -4.931  1   19.994 ? 226  TYR B CG  1 
ATOM   5814 C  CD1 . TYR B 1 234 ? 28.785  -25.812 -5.718  1   20.372 ? 226  TYR B CD1 1 
ATOM   5815 C  CD2 . TYR B 1 234 ? 27.083  -24.734 -4.36   1   20.992 ? 226  TYR B CD2 1 
ATOM   5816 C  CE1 . TYR B 1 234 ? 27.924  -26.881 -5.926  1   20.92  ? 226  TYR B CE1 1 
ATOM   5817 C  CE2 . TYR B 1 234 ? 26.194  -25.784 -4.606  1   21.329 ? 226  TYR B CE2 1 
ATOM   5818 C  CZ  . TYR B 1 234 ? 26.625  -26.846 -5.408  1   21.74  ? 226  TYR B CZ  1 
ATOM   5819 O  OH  . TYR B 1 234 ? 25.805  -27.921 -5.625  1   23.014 ? 226  TYR B OH  1 
ATOM   5820 N  N   . TYR B 1 235 ? 28.187  -22.44  -7.811  1   20.857 ? 227  TYR B N   1 
ATOM   5821 C  CA  . TYR B 1 235 ? 26.954  -22.098 -8.499  1   20.422 ? 227  TYR B CA  1 
ATOM   5822 C  C   . TYR B 1 235 ? 26.004  -23.295 -8.454  1   21.973 ? 227  TYR B C   1 
ATOM   5823 O  O   . TYR B 1 235 ? 26.434  -24.452 -8.542  1   19.766 ? 227  TYR B O   1 
ATOM   5824 C  CB  . TYR B 1 235 ? 27.323  -21.756 -9.964  1   19.663 ? 227  TYR B CB  1 
ATOM   5825 C  CG  . TYR B 1 235 ? 26.248  -22.107 -10.996 1   22.586 ? 227  TYR B CG  1 
ATOM   5826 C  CD1 . TYR B 1 235 ? 25.123  -21.277 -11.168 1   21.75  ? 227  TYR B CD1 1 
ATOM   5827 C  CD2 . TYR B 1 235 ? 26.375  -23.24  -11.821 1   21.937 ? 227  TYR B CD2 1 
ATOM   5828 C  CE1 . TYR B 1 235 ? 24.141  -21.569 -12.111 1   21.994 ? 227  TYR B CE1 1 
ATOM   5829 C  CE2 . TYR B 1 235 ? 25.39   -23.541 -12.766 1   23.16  ? 227  TYR B CE2 1 
ATOM   5830 C  CZ  . TYR B 1 235 ? 24.277  -22.706 -12.901 1   23.703 ? 227  TYR B CZ  1 
ATOM   5831 O  OH  . TYR B 1 235 ? 23.337  -22.95  -13.851 1   23.809 ? 227  TYR B OH  1 
ATOM   5832 N  N   . PHE B 1 236 ? 24.693  -23.018 -8.356  1   20.435 ? 228  PHE B N   1 
ATOM   5833 C  CA  . PHE B 1 236 ? 23.721  -24.108 -8.338  1   19.555 ? 228  PHE B CA  1 
ATOM   5834 C  C   . PHE B 1 236 ? 22.408  -23.611 -8.95   1   20.947 ? 228  PHE B C   1 
ATOM   5835 O  O   . PHE B 1 236 ? 22.104  -22.409 -9.004  1   20.269 ? 228  PHE B O   1 
ATOM   5836 C  CB  . PHE B 1 236 ? 23.555  -24.643 -6.89   1   21.353 ? 228  PHE B CB  1 
ATOM   5837 C  CG  . PHE B 1 236 ? 22.988  -23.555 -5.966  1   21.218 ? 228  PHE B CG  1 
ATOM   5838 C  CD1 . PHE B 1 236 ? 21.612  -23.298 -5.965  1   21.231 ? 228  PHE B CD1 1 
ATOM   5839 C  CD2 . PHE B 1 236 ? 23.821  -22.738 -5.188  1   19.213 ? 228  PHE B CD2 1 
ATOM   5840 C  CE1 . PHE B 1 236 ? 21.075  -22.269 -5.195  1   21.187 ? 228  PHE B CE1 1 
ATOM   5841 C  CE2 . PHE B 1 236 ? 23.267  -21.758 -4.346  1   20.586 ? 228  PHE B CE2 1 
ATOM   5842 C  CZ  . PHE B 1 236 ? 21.885  -21.506 -4.397  1   21.12  ? 228  PHE B CZ  1 
ATOM   5843 N  N   . GLU B 1 237 ? 21.6    -24.586 -9.369  1   18.71  ? 229  GLU B N   1 
ATOM   5844 C  CA  . GLU B 1 237 ? 20.174  -24.415 -9.618  1   20.555 ? 229  GLU B CA  1 
ATOM   5845 C  C   . GLU B 1 237 ? 19.433  -25.557 -8.93   1   23.491 ? 229  GLU B C   1 
ATOM   5846 O  O   . GLU B 1 237 ? 19.755  -26.73  -9.146  1   21.313 ? 229  GLU B O   1 
ATOM   5847 C  CB  . GLU B 1 237 ? 19.877  -24.379 -11.124 1   21.71  ? 229  GLU B CB  1 
ATOM   5848 C  CG  . GLU B 1 237 ? 20.643  -23.274 -11.843 1   21.449 ? 229  GLU B CG  1 
ATOM   5849 C  CD  . GLU B 1 237 ? 20.119  -22.867 -13.203 1   23.074 ? 229  GLU B CD  1 
ATOM   5850 O  OE1 . GLU B 1 237 ? 18.949  -23.208 -13.521 1   21.812 ? 229  GLU B OE1 1 
ATOM   5851 O  OE2 . GLU B 1 237 ? 20.853  -22.165 -13.917 1   21.881 ? 229  GLU B OE2 1 
ATOM   5852 N  N   . VAL B 1 238 ? 18.496  -25.18  -8.035  1   21.397 ? 230  VAL B N   1 
ATOM   5853 C  CA  . VAL B 1 238 ? 17.639  -26.108 -7.314  1   21.984 ? 230  VAL B CA  1 
ATOM   5854 C  C   . VAL B 1 238 ? 16.298  -26.101 -8.022  1   22.278 ? 230  VAL B C   1 
ATOM   5855 O  O   . VAL B 1 238 ? 15.675  -25.052 -8.138  1   20.572 ? 230  VAL B O   1 
ATOM   5856 C  CB  . VAL B 1 238 ? 17.543  -25.736 -5.821  1   20.843 ? 230  VAL B CB  1 
ATOM   5857 C  CG1 . VAL B 1 238 ? 16.595  -26.647 -5.053  1   22.276 ? 230  VAL B CG1 1 
ATOM   5858 C  CG2 . VAL B 1 238 ? 18.951  -25.809 -5.181  1   22.203 ? 230  VAL B CG2 1 
ATOM   5859 N  N   . ASP B 1 239 ? 15.841  -27.289 -8.432  1   22.671 ? 231  ASP B N   1 
ATOM   5860 C  CA  . ASP B 1 239 ? 14.612  -27.373 -9.201  1   25.467 ? 231  ASP B CA  1 
ATOM   5861 C  C   . ASP B 1 239 ? 13.399  -27.199 -8.281  1   24.727 ? 231  ASP B C   1 
ATOM   5862 O  O   . ASP B 1 239 ? 13.572  -27.207 -7.054  1   23.063 ? 231  ASP B O   1 
ATOM   5863 C  CB  . ASP B 1 239 ? 14.608  -28.612 -10.099 1   25.697 ? 231  ASP B CB  1 
ATOM   5864 C  CG  . ASP B 1 239 ? 14.221  -29.932 -9.466  1   30.099 ? 231  ASP B CG  1 
ATOM   5865 O  OD1 . ASP B 1 239 ? 14.03   -29.998 -8.231  1   30.823 ? 231  ASP B OD1 1 
ATOM   5866 O  OD2 . ASP B 1 239 ? 14.192  -30.918 -10.203 1   30.613 ? 231  ASP B OD2 1 
ATOM   5867 N  N   . PRO B 1 240 ? 12.154  -27.054 -8.836  1   24.472 ? 232  PRO B N   1 
ATOM   5868 C  CA  . PRO B 1 240 ? 10.939  -26.95  -8.034  1   25.907 ? 232  PRO B CA  1 
ATOM   5869 C  C   . PRO B 1 240 ? 10.68   -28.096 -7.055  1   28.034 ? 232  PRO B C   1 
ATOM   5870 O  O   . PRO B 1 240 ? 9.862   -27.946 -6.152  1   27.345 ? 232  PRO B O   1 
ATOM   5871 C  CB  . PRO B 1 240 ? 9.824   -26.771 -9.066  1   26.825 ? 232  PRO B CB  1 
ATOM   5872 C  CG  . PRO B 1 240 ? 10.539  -26.148 -10.251 1   26.351 ? 232  PRO B CG  1 
ATOM   5873 C  CD  . PRO B 1 240 ? 11.874  -26.828 -10.273 1   26.511 ? 232  PRO B CD  1 
ATOM   5874 N  N   . SER B 1 241 ? 11.411  -29.207 -7.208  1   25.514 ? 233  SER B N   1 
ATOM   5875 C  CA  . SER B 1 241 ? 11.249  -30.351 -6.342  1   28.586 ? 233  SER B CA  1 
ATOM   5876 C  C   . SER B 1 241 ? 12.294  -30.35  -5.23   1   27.255 ? 233  SER B C   1 
ATOM   5877 O  O   . SER B 1 241 ? 12.285  -31.244 -4.406  1   30.115 ? 233  SER B O   1 
ATOM   5878 C  CB  . SER B 1 241 ? 11.208  -31.654 -7.173  1   34.139 ? 233  SER B CB  1 
ATOM   5879 O  OG  . SER B 1 241 ? 12.535  -32.102 -7.418  1   42.052 ? 233  SER B OG  1 
ATOM   5880 N  N   . GLY B 1 242 ? 13.211  -29.375 -5.216  1   26.227 ? 234  GLY B N   1 
ATOM   5881 C  CA  . GLY B 1 242 ? 14.198  -29.233 -4.154  1   24.17  ? 234  GLY B CA  1 
ATOM   5882 C  C   . GLY B 1 242 ? 15.525  -29.958 -4.421  1   27.226 ? 234  GLY B C   1 
ATOM   5883 O  O   . GLY B 1 242 ? 16.356  -30.064 -3.52   1   26.537 ? 234  GLY B O   1 
ATOM   5884 N  N   . LYS B 1 243 ? 15.758  -30.359 -5.676  1   27.596 ? 235  LYS B N   1 
ATOM   5885 C  CA  . LYS B 1 243 ? 16.964  -31.091 -6.06   1   29.6   ? 235  LYS B CA  1 
ATOM   5886 C  C   . LYS B 1 243 ? 17.919  -30.162 -6.821  1   24.454 ? 235  LYS B C   1 
ATOM   5887 O  O   . LYS B 1 243 ? 17.49   -29.406 -7.693  1   21.67  ? 235  LYS B O   1 
ATOM   5888 C  CB  . LYS B 1 243 ? 16.488  -32.164 -7.052  1   31.733 ? 235  LYS B CB  1 
ATOM   5889 C  CG  . LYS B 1 243 ? 17.51   -33.226 -7.396  1   42.898 ? 235  LYS B CG  1 
ATOM   5890 C  CD  . LYS B 1 243 ? 17.109  -33.881 -8.72   1   56.73  ? 235  LYS B CD  1 
ATOM   5891 C  CE  . LYS B 1 243 ? 17.58   -35.278 -8.968  1   63.123 ? 235  LYS B CE  1 
ATOM   5892 N  NZ  . LYS B 1 243 ? 18.961  -35.511 -8.541  1   56.406 ? 235  LYS B NZ  1 
ATOM   5893 N  N   . VAL B 1 244 ? 19.226  -30.32  -6.561  1   26.861 ? 236  VAL B N   1 
ATOM   5894 C  CA  . VAL B 1 244 ? 20.236  -29.584 -7.309  1   26.306 ? 236  VAL B CA  1 
ATOM   5895 C  C   . VAL B 1 244 ? 20.342  -30.268 -8.679  1   26.3   ? 236  VAL B C   1 
ATOM   5896 O  O   . VAL B 1 244 ? 20.728  -31.422 -8.746  1   29.978 ? 236  VAL B O   1 
ATOM   5897 C  CB  . VAL B 1 244 ? 21.574  -29.591 -6.54   1   26.185 ? 236  VAL B CB  1 
ATOM   5898 C  CG1 . VAL B 1 244 ? 22.741  -29.007 -7.343  1   24.575 ? 236  VAL B CG1 1 
ATOM   5899 C  CG2 . VAL B 1 244 ? 21.448  -28.977 -5.14   1   26.055 ? 236  VAL B CG2 1 
ATOM   5900 N  N   . VAL B 1 245 ? 19.985  -29.55  -9.736  1   23.489 ? 237  VAL B N   1 
ATOM   5901 C  CA  . VAL B 1 245 ? 19.92   -30.089 -11.089 1   24.866 ? 237  VAL B CA  1 
ATOM   5902 C  C   . VAL B 1 245 ? 21.099  -29.586 -11.92  1   27.43  ? 237  VAL B C   1 
ATOM   5903 O  O   . VAL B 1 245 ? 21.427  -30.202 -12.925 1   26.343 ? 237  VAL B O   1 
ATOM   5904 C  CB  . VAL B 1 245 ? 18.567  -29.874 -11.8   1   27.336 ? 237  VAL B CB  1 
ATOM   5905 C  CG1 . VAL B 1 245 ? 17.49   -30.722 -11.136 1   27.177 ? 237  VAL B CG1 1 
ATOM   5906 C  CG2 . VAL B 1 245 ? 18.149  -28.409 -11.859 1   27.376 ? 237  VAL B CG2 1 
ATOM   5907 N  N   . ARG B 1 246 ? 21.729  -28.474 -11.506 1   24.743 ? 238  ARG B N   1 
ATOM   5908 C  CA  . ARG B 1 246 ? 22.913  -27.923 -12.157 1   24.748 ? 238  ARG B CA  1 
ATOM   5909 C  C   . ARG B 1 246 ? 23.797  -27.371 -11.053 1   26.86  ? 238  ARG B C   1 
ATOM   5910 O  O   . ARG B 1 246 ? 23.274  -26.815 -10.074 1   24.334 ? 238  ARG B O   1 
ATOM   5911 C  CB  . ARG B 1 246 ? 22.541  -26.708 -13.016 1   25.226 ? 238  ARG B CB  1 
ATOM   5912 C  CG  . ARG B 1 246 ? 21.771  -27.079 -14.284 1   26.118 ? 238  ARG B CG  1 
ATOM   5913 C  CD  . ARG B 1 246 ? 21.128  -25.831 -14.861 1   27.385 ? 238  ARG B CD  1 
ATOM   5914 N  NE  . ARG B 1 246 ? 20.663  -26.021 -16.242 1   28.665 ? 238  ARG B NE  1 
ATOM   5915 C  CZ  . ARG B 1 246 ? 20.119  -25.095 -17.011 1   28.633 ? 238  ARG B CZ  1 
ATOM   5916 N  NH1 . ARG B 1 246 ? 19.693  -23.953 -16.523 1   27.679 ? 238  ARG B NH1 1 
ATOM   5917 N  NH2 . ARG B 1 246 ? 19.93   -25.321 -18.313 1   29.909 ? 238  ARG B NH2 1 
ATOM   5918 N  N   . ASP B 1 247 ? 25.108  -27.562 -11.193 1   24.194 ? 239  ASP B N   1 
ATOM   5919 C  CA  . ASP B 1 247 ? 26.038  -26.901 -10.281 1   22.264 ? 239  ASP B CA  1 
ATOM   5920 C  C   . ASP B 1 247 ? 27.401  -26.85  -10.934 1   24.063 ? 239  ASP B C   1 
ATOM   5921 O  O   . ASP B 1 247 ? 27.611  -27.441 -12.004 1   25.113 ? 239  ASP B O   1 
ATOM   5922 C  CB  . ASP B 1 247 ? 26.06   -27.497 -8.873  1   21.334 ? 239  ASP B CB  1 
ATOM   5923 C  CG  . ASP B 1 247 ? 26.646  -28.903 -8.721  1   24.516 ? 239  ASP B CG  1 
ATOM   5924 O  OD1 . ASP B 1 247 ? 27.081  -29.509 -9.743  1   26.645 ? 239  ASP B OD1 1 
ATOM   5925 O  OD2 . ASP B 1 247 ? 26.614  -29.427 -7.609  1   23.97  ? 239  ASP B OD2 1 
ATOM   5926 N  N   . LEU B 1 248 ? 28.31   -26.101 -10.31  1   23.783 ? 240  LEU B N   1 
ATOM   5927 C  CA  . LEU B 1 248 ? 29.66   -25.892 -10.827 1   22.305 ? 240  LEU B CA  1 
ATOM   5928 C  C   . LEU B 1 248 ? 30.457  -25.248 -9.706  1   21.947 ? 240  LEU B C   1 
ATOM   5929 O  O   . LEU B 1 248 ? 29.985  -24.296 -9.068  1   21.63  ? 240  LEU B O   1 
ATOM   5930 C  CB  . LEU B 1 248 ? 29.676  -24.97  -12.051 1   23.7   ? 240  LEU B CB  1 
ATOM   5931 C  CG  . LEU B 1 248 ? 31.047  -24.759 -12.718 1   26.356 ? 240  LEU B CG  1 
ATOM   5932 C  CD1 . LEU B 1 248 ? 31.563  -26.049 -13.392 1   28.255 ? 240  LEU B CD1 1 
ATOM   5933 C  CD2 . LEU B 1 248 ? 30.961  -23.573 -13.695 1   25.915 ? 240  LEU B CD2 1 
ATOM   5934 N  N   . TRP B 1 249 ? 31.675  -25.776 -9.502  1   21.869 ? 241  TRP B N   1 
ATOM   5935 C  CA  . TRP B 1 249 ? 32.67   -25.088 -8.681  1   22.277 ? 241  TRP B CA  1 
ATOM   5936 C  C   . TRP B 1 249 ? 33.58   -24.226 -9.547  1   27.03  ? 241  TRP B C   1 
ATOM   5937 O  O   . TRP B 1 249 ? 34.011  -24.642 -10.62  1   23.764 ? 241  TRP B O   1 
ATOM   5938 C  CB  . TRP B 1 249 ? 33.484  -26.119 -7.906  1   21.231 ? 241  TRP B CB  1 
ATOM   5939 C  CG  . TRP B 1 249 ? 32.671  -26.728 -6.797  1   22.232 ? 241  TRP B CG  1 
ATOM   5940 C  CD1 . TRP B 1 249 ? 31.872  -27.829 -6.873  1   23.099 ? 241  TRP B CD1 1 
ATOM   5941 C  CD2 . TRP B 1 249 ? 32.618  -26.262 -5.436  1   24.993 ? 241  TRP B CD2 1 
ATOM   5942 N  NE1 . TRP B 1 249 ? 31.35   -28.116 -5.635  1   25.293 ? 241  TRP B NE1 1 
ATOM   5943 C  CE2 . TRP B 1 249 ? 31.765  -27.157 -4.746  1   25.031 ? 241  TRP B CE2 1 
ATOM   5944 C  CE3 . TRP B 1 249 ? 33.202  -25.171 -4.758  1   27.246 ? 241  TRP B CE3 1 
ATOM   5945 C  CZ2 . TRP B 1 249 ? 31.488  -27.009 -3.38   1   24.063 ? 241  TRP B CZ2 1 
ATOM   5946 C  CZ3 . TRP B 1 249 ? 32.921  -25.027 -3.41   1   30.024 ? 241  TRP B CZ3 1 
ATOM   5947 C  CH2 . TRP B 1 249 ? 32.07   -25.934 -2.745  1   24.264 ? 241  TRP B CH2 1 
ATOM   5948 N  N   . LEU B 1 250 ? 33.829  -23.003 -9.075  1   23.936 ? 242  LEU B N   1 
ATOM   5949 C  CA  . LEU B 1 250 ? 34.636  -22.024 -9.784  1   24.258 ? 242  LEU B CA  1 
ATOM   5950 C  C   . LEU B 1 250 ? 35.307  -21.156 -8.725  1   22.002 ? 242  LEU B C   1 
ATOM   5951 O  O   . LEU B 1 250 ? 35.279  -21.491 -7.536  1   20.559 ? 242  LEU B O   1 
ATOM   5952 C  CB  . LEU B 1 250 ? 33.79   -21.201 -10.762 1   22.941 ? 242  LEU B CB  1 
ATOM   5953 C  CG  . LEU B 1 250 ? 32.645  -20.388 -10.123 1   20.821 ? 242  LEU B CG  1 
ATOM   5954 C  CD1 . LEU B 1 250 ? 32.684  -18.913 -10.638 1   21.683 ? 242  LEU B CD1 1 
ATOM   5955 C  CD2 . LEU B 1 250 ? 31.303  -21.043 -10.392 1   21.084 ? 242  LEU B CD2 1 
ATOM   5956 N  N   . GLU B 1 251 ? 35.995  -20.101 -9.179  1   23.127 ? 243  GLU B N   1 
ATOM   5957 C  CA  . GLU B 1 251 ? 36.68   -19.199 -8.262  1   22.627 ? 243  GLU B CA  1 
ATOM   5958 C  C   . GLU B 1 251 ? 36.424  -17.773 -8.725  1   23.937 ? 243  GLU B C   1 
ATOM   5959 O  O   . GLU B 1 251 ? 36.192  -17.508 -9.916  1   25.604 ? 243  GLU B O   1 
ATOM   5960 C  CB  . GLU B 1 251 ? 38.191  -19.414 -8.131  1   27.182 ? 243  GLU B CB  1 
ATOM   5961 C  CG  . GLU B 1 251 ? 38.565  -20.788 -7.565  1   30.36  ? 243  GLU B CG  1 
ATOM   5962 C  CD  . GLU B 1 251 ? 40.075  -20.96  -7.564  1   42.343 ? 243  GLU B CD  1 
ATOM   5963 O  OE1 . GLU B 1 251 ? 40.66   -21.001 -8.644  1   45.405 ? 243  GLU B OE1 1 
ATOM   5964 O  OE2 . GLU B 1 251 ? 40.67   -20.998 -6.481  1   49.677 ? 243  GLU B OE2 1 
ATOM   5965 N  N   . ALA B 1 252 ? 36.418  -16.87  -7.747  1   22.236 ? 244  ALA B N   1 
ATOM   5966 C  CA  . ALA B 1 252 ? 36.45   -15.449 -8.013  1   23.746 ? 244  ALA B CA  1 
ATOM   5967 C  C   . ALA B 1 252 ? 37.911  -15.002 -8.176  1   22.737 ? 244  ALA B C   1 
ATOM   5968 O  O   . ALA B 1 252 ? 38.833  -15.65  -7.632  1   22.168 ? 244  ALA B O   1 
ATOM   5969 C  CB  . ALA B 1 252 ? 35.716  -14.687 -6.895  1   23.213 ? 244  ALA B CB  1 
ATOM   5970 N  N   . PRO B 1 253 ? 38.169  -13.891 -8.911  1   20.915 ? 245  PRO B N   1 
ATOM   5971 C  CA  . PRO B 1 253 ? 39.549  -13.412 -9.121  1   22.79  ? 245  PRO B CA  1 
ATOM   5972 C  C   . PRO B 1 253 ? 40.277  -13.008 -7.837  1   23.766 ? 245  PRO B C   1 
ATOM   5973 O  O   . PRO B 1 253 ? 41.507  -13.066 -7.767  1   24.875 ? 245  PRO B O   1 
ATOM   5974 C  CB  . PRO B 1 253 ? 39.389  -12.243 -10.108 1   22.853 ? 245  PRO B CB  1 
ATOM   5975 C  CG  . PRO B 1 253 ? 37.917  -11.85  -9.975  1   22.46  ? 245  PRO B CG  1 
ATOM   5976 C  CD  . PRO B 1 253 ? 37.188  -13.125 -9.705  1   21.369 ? 245  PRO B CD  1 
ATOM   5977 N  N   . TRP B 1 254 ? 39.525  -12.558 -6.836  1   20.363 ? 246  TRP B N   1 
ATOM   5978 C  CA  . TRP B 1 254 ? 40.049  -12.376 -5.484  1   18.55  ? 246  TRP B CA  1 
ATOM   5979 C  C   . TRP B 1 254 ? 38.922  -12.757 -4.539  1   19.802 ? 246  TRP B C   1 
ATOM   5980 O  O   . TRP B 1 254 ? 37.803  -12.963 -5.018  1   22.904 ? 246  TRP B O   1 
ATOM   5981 C  CB  . TRP B 1 254 ? 40.534  -10.93  -5.223  1   21.149 ? 246  TRP B CB  1 
ATOM   5982 C  CG  . TRP B 1 254 ? 39.448  -9.871  -5.104  1   21.678 ? 246  TRP B CG  1 
ATOM   5983 C  CD1 . TRP B 1 254 ? 38.917  -9.386  -3.936  1   22.65  ? 246  TRP B CD1 1 
ATOM   5984 C  CD2 . TRP B 1 254 ? 38.783  -9.148  -6.17   1   22.909 ? 246  TRP B CD2 1 
ATOM   5985 N  NE1 . TRP B 1 254 ? 37.958  -8.442  -4.203  1   20.392 ? 246  TRP B NE1 1 
ATOM   5986 C  CE2 . TRP B 1 254 ? 37.855  -8.267  -5.561  1   21.45  ? 246  TRP B CE2 1 
ATOM   5987 C  CE3 . TRP B 1 254 ? 38.887  -9.152  -7.576  1   22.161 ? 246  TRP B CE3 1 
ATOM   5988 C  CZ2 . TRP B 1 254 ? 37.027  -7.416  -6.295  1   20.788 ? 246  TRP B CZ2 1 
ATOM   5989 C  CZ3 . TRP B 1 254 ? 38.064  -8.302  -8.301  1   23.657 ? 246  TRP B CZ3 1 
ATOM   5990 C  CH2 . TRP B 1 254 ? 37.174  -7.416  -7.676  1   22.472 ? 246  TRP B CH2 1 
ATOM   5991 N  N   . CYS B 1 255 ? 39.194  -12.798 -3.217  1   20.214 ? 247  CYS B N   1 
ATOM   5992 C  CA  . CYS B 1 255 ? 38.109  -13.124 -2.307  1   22.513 ? 247  CYS B CA  1 
ATOM   5993 C  C   . CYS B 1 255 ? 37.276  -11.856 -2.132  1   20.429 ? 247  CYS B C   1 
ATOM   5994 O  O   . CYS B 1 255 ? 37.633  -10.992 -1.348  1   21.406 ? 247  CYS B O   1 
ATOM   5995 C  CB  . CYS B 1 255 ? 38.577  -13.727 -0.974  1   22.555 ? 247  CYS B CB  1 
ATOM   5996 S  SG  . CYS B 1 255 ? 37.142  -14.196 0.045   1   23.994 ? 247  CYS B SG  1 
ATOM   5997 N  N   . ALA B 1 256 ? 36.212  -11.76  -2.932  1   19.116 ? 248  ALA B N   1 
ATOM   5998 C  CA  . ALA B 1 256 ? 35.423  -10.542 -3.088  1   19.239 ? 248  ALA B CA  1 
ATOM   5999 C  C   . ALA B 1 256 ? 34.092  -10.688 -2.364  1   19.16  ? 248  ALA B C   1 
ATOM   6000 O  O   . ALA B 1 256 ? 33.574  -11.794 -2.207  1   18.969 ? 248  ALA B O   1 
ATOM   6001 C  CB  . ALA B 1 256 ? 35.178  -10.297 -4.587  1   19.36  ? 248  ALA B CB  1 
ATOM   6002 N  N   . PHE B 1 257 ? 33.489  -9.54   -2.048  1   19.976 ? 249  PHE B N   1 
ATOM   6003 C  CA  . PHE B 1 257 ? 32.186  -9.511  -1.391  1   20.528 ? 249  PHE B CA  1 
ATOM   6004 C  C   . PHE B 1 257 ? 31.154  -9.572  -2.514  1   21.711 ? 249  PHE B C   1 
ATOM   6005 O  O   . PHE B 1 257 ? 30.883  -8.564  -3.165  1   20.52  ? 249  PHE B O   1 
ATOM   6006 C  CB  . PHE B 1 257 ? 32.178  -8.198  -0.622  1   18.05  ? 249  PHE B CB  1 
ATOM   6007 C  CG  . PHE B 1 257 ? 31.113  -8      0.441   1   19.43  ? 249  PHE B CG  1 
ATOM   6008 C  CD1 . PHE B 1 257 ? 29.86   -8.64   0.387   1   20.821 ? 249  PHE B CD1 1 
ATOM   6009 C  CD2 . PHE B 1 257 ? 31.383  -7.134  1.502   1   19.702 ? 249  PHE B CD2 1 
ATOM   6010 C  CE1 . PHE B 1 257 ? 28.903  -8.414  1.39    1   18.72  ? 249  PHE B CE1 1 
ATOM   6011 C  CE2 . PHE B 1 257 ? 30.418  -6.917  2.51    1   20.052 ? 249  PHE B CE2 1 
ATOM   6012 C  CZ  . PHE B 1 257 ? 29.197  -7.557  2.44    1   21.371 ? 249  PHE B CZ  1 
ATOM   6013 N  N   . ILE B 1 258 ? 30.607  -10.773 -2.721  1   17.953 ? 250  ILE B N   1 
ATOM   6014 C  CA  . ILE B 1 258 ? 29.72   -11.042 -3.851  1   17.635 ? 250  ILE B CA  1 
ATOM   6015 C  C   . ILE B 1 258 ? 28.297  -11.119 -3.301  1   17.013 ? 250  ILE B C   1 
ATOM   6016 O  O   . ILE B 1 258 ? 27.757  -12.193 -3.063  1   19.147 ? 250  ILE B O   1 
ATOM   6017 C  CB  . ILE B 1 258 ? 30.092  -12.292 -4.68   1   19.042 ? 250  ILE B CB  1 
ATOM   6018 C  CG1 . ILE B 1 258 ? 31.592  -12.346 -5.022  1   20.538 ? 250  ILE B CG1 1 
ATOM   6019 C  CG2 . ILE B 1 258 ? 29.2    -12.324 -5.95   1   21.066 ? 250  ILE B CG2 1 
ATOM   6020 C  CD1 . ILE B 1 258 ? 31.982  -13.548 -5.888  1   21.415 ? 250  ILE B CD1 1 
ATOM   6021 N  N   . HIS B 1 259 ? 27.696  -9.948  -3.096  1   18.797 ? 251  HIS B N   1 
ATOM   6022 C  CA  . HIS B 1 259 ? 26.432  -9.883  -2.368  1   19.234 ? 251  HIS B CA  1 
ATOM   6023 C  C   . HIS B 1 259 ? 25.254  -10.316 -3.238  1   18.619 ? 251  HIS B C   1 
ATOM   6024 O  O   . HIS B 1 259 ? 24.353  -11.013 -2.773  1   19.375 ? 251  HIS B O   1 
ATOM   6025 C  CB  . HIS B 1 259 ? 26.202  -8.433  -1.895  1   18.455 ? 251  HIS B CB  1 
ATOM   6026 C  CG  . HIS B 1 259 ? 24.908  -8.325  -1.102  1   20.002 ? 251  HIS B CG  1 
ATOM   6027 N  ND1 . HIS B 1 259 ? 24.739  -9.008  0.092   1   19.274 ? 251  HIS B ND1 1 
ATOM   6028 C  CD2 . HIS B 1 259 ? 23.754  -7.668  -1.321  1   19.326 ? 251  HIS B CD2 1 
ATOM   6029 C  CE1 . HIS B 1 259 ? 23.534  -8.758  0.586   1   20.985 ? 251  HIS B CE1 1 
ATOM   6030 N  NE2 . HIS B 1 259 ? 22.925  -7.926  -0.236  1   19.842 ? 251  HIS B NE2 1 
ATOM   6031 N  N   . ASP B 1 260 ? 25.257  -9.867  -4.504  1   19.38  ? 252  ASP B N   1 
ATOM   6032 C  CA  . ASP B 1 260 ? 24.071  -10.003 -5.334  1   20.189 ? 252  ASP B CA  1 
ATOM   6033 C  C   . ASP B 1 260 ? 24.513  -10.458 -6.728  1   19.469 ? 252  ASP B C   1 
ATOM   6034 O  O   . ASP B 1 260 ? 25.71   -10.551 -7.023  1   19.351 ? 252  ASP B O   1 
ATOM   6035 C  CB  . ASP B 1 260 ? 23.297  -8.686  -5.351  1   21.655 ? 252  ASP B CB  1 
ATOM   6036 C  CG  . ASP B 1 260 ? 21.825  -8.751  -5.795  1   22.113 ? 252  ASP B CG  1 
ATOM   6037 O  OD1 . ASP B 1 260 ? 21.333  -9.862  -6.115  1   20.175 ? 252  ASP B OD1 1 
ATOM   6038 O  OD2 . ASP B 1 260 ? 21.164  -7.678  -5.794  1   23.609 ? 252  ASP B OD2 1 
ATOM   6039 N  N   . CYS B 1 261 ? 23.514  -10.685 -7.581  1   19.391 ? 253  CYS B N   1 
ATOM   6040 C  CA  . CYS B 1 261 ? 23.714  -11.268 -8.891  1   20.139 ? 253  CYS B CA  1 
ATOM   6041 C  C   . CYS B 1 261 ? 22.521  -10.88  -9.761  1   21.315 ? 253  CYS B C   1 
ATOM   6042 O  O   . CYS B 1 261 ? 21.564  -10.236 -9.303  1   21.823 ? 253  CYS B O   1 
ATOM   6043 C  CB  . CYS B 1 261 ? 23.907  -12.779 -8.75   1   22.193 ? 253  CYS B CB  1 
ATOM   6044 S  SG  . CYS B 1 261 ? 22.425  -13.636 -8.14   1   22.121 ? 253  CYS B SG  1 
ATOM   6045 N  N   . ALA B 1 262 ? 22.605  -11.261 -11.036 1   21.881 ? 254  ALA B N   1 
ATOM   6046 C  CA  . ALA B 1 262 ? 21.474  -11.1   -11.939 1   21.15  ? 254  ALA B CA  1 
ATOM   6047 C  C   . ALA B 1 262 ? 21.294  -12.387 -12.738 1   20.542 ? 254  ALA B C   1 
ATOM   6048 O  O   . ALA B 1 262 ? 22.268  -12.988 -13.182 1   23.174 ? 254  ALA B O   1 
ATOM   6049 C  CB  . ALA B 1 262 ? 21.733  -9.892  -12.836 1   20.296 ? 254  ALA B CB  1 
ATOM   6050 N  N   . LEU B 1 263 ? 20.03   -12.792 -12.888 1   19.456 ? 255  LEU B N   1 
ATOM   6051 C  CA  . LEU B 1 263 ? 19.689  -13.978 -13.639 1   20.415 ? 255  LEU B CA  1 
ATOM   6052 C  C   . LEU B 1 263 ? 19.172  -13.518 -14.999 1   23.443 ? 255  LEU B C   1 
ATOM   6053 O  O   . LEU B 1 263 ? 18.34   -12.607 -15.078 1   27.116 ? 255  LEU B O   1 
ATOM   6054 C  CB  . LEU B 1 263 ? 18.575  -14.743 -12.922 1   20.634 ? 255  LEU B CB  1 
ATOM   6055 C  CG  . LEU B 1 263 ? 18.143  -16.061 -13.572 1   19.345 ? 255  LEU B CG  1 
ATOM   6056 C  CD1 . LEU B 1 263 ? 19.28   -17.104 -13.502 1   20.155 ? 255  LEU B CD1 1 
ATOM   6057 C  CD2 . LEU B 1 263 ? 16.883  -16.589 -12.892 1   20.865 ? 255  LEU B CD2 1 
ATOM   6058 N  N   . THR B 1 264 ? 19.66   -14.202 -16.038 1   21.539 ? 256  THR B N   1 
ATOM   6059 C  CA  . THR B 1 264 ? 19.119  -14.043 -17.388 1   24.542 ? 256  THR B CA  1 
ATOM   6060 C  C   . THR B 1 264 ? 18.774  -15.437 -17.938 1   24.316 ? 256  THR B C   1 
ATOM   6061 O  O   . THR B 1 264 ? 19.078  -16.445 -17.305 1   26.06  ? 256  THR B O   1 
ATOM   6062 C  CB  . THR B 1 264 ? 20.12   -13.296 -18.284 1   24.312 ? 256  THR B CB  1 
ATOM   6063 O  OG1 . THR B 1 264 ? 21.131  -14.198 -18.695 1   28.711 ? 256  THR B OG1 1 
ATOM   6064 C  CG2 . THR B 1 264 ? 20.759  -12.065 -17.659 1   27.364 ? 256  THR B CG2 1 
ATOM   6065 N  N   . PRO B 1 265 ? 18.178  -15.581 -19.159 1   23.066 ? 257  PRO B N   1 
ATOM   6066 C  CA  . PRO B 1 265 ? 17.84   -16.906 -19.652 1   23.127 ? 257  PRO B CA  1 
ATOM   6067 C  C   . PRO B 1 265 ? 19.015  -17.871 -19.702 1   22.655 ? 257  PRO B C   1 
ATOM   6068 O  O   . PRO B 1 265 ? 18.855  -19.068 -19.444 1   25.327 ? 257  PRO B O   1 
ATOM   6069 C  CB  . PRO B 1 265 ? 17.171  -16.625 -21.008 1   24.954 ? 257  PRO B CB  1 
ATOM   6070 C  CG  . PRO B 1 265 ? 16.553  -15.277 -20.762 1   22.856 ? 257  PRO B CG  1 
ATOM   6071 C  CD  . PRO B 1 265 ? 17.601  -14.515 -19.995 1   23.318 ? 257  PRO B CD  1 
ATOM   6072 N  N   . ASN B 1 266 ? 20.199  -17.335 -20.031 1   23.159 ? 258  ASN B N   1 
ATOM   6073 C  CA  . ASN B 1 266 ? 21.368  -18.175 -20.321 1   26.207 ? 258  ASN B CA  1 
ATOM   6074 C  C   . ASN B 1 266 ? 22.514  -17.977 -19.321 1   24.378 ? 258  ASN B C   1 
ATOM   6075 O  O   . ASN B 1 266 ? 23.505  -18.704 -19.427 1   24.279 ? 258  ASN B O   1 
ATOM   6076 C  CB  . ASN B 1 266 ? 21.87   -18.012 -21.766 1   25.502 ? 258  ASN B CB  1 
ATOM   6077 C  CG  . ASN B 1 266 ? 20.761  -18.399 -22.713 1   27.151 ? 258  ASN B CG  1 
ATOM   6078 O  OD1 . ASN B 1 266 ? 20.272  -19.534 -22.63  1   29.771 ? 258  ASN B OD1 1 
ATOM   6079 N  ND2 . ASN B 1 266 ? 20.272  -17.461 -23.51  1   25.695 ? 258  ASN B ND2 1 
ATOM   6080 N  N   . TYR B 1 267 ? 22.377  -17.048 -18.355 1   23.177 ? 259  TYR B N   1 
ATOM   6081 C  CA  . TYR B 1 267 ? 23.529  -16.76  -17.49  1   22.946 ? 259  TYR B CA  1 
ATOM   6082 C  C   . TYR B 1 267 ? 23.083  -16.469 -16.059 1   24.158 ? 259  TYR B C   1 
ATOM   6083 O  O   . TYR B 1 267 ? 22.009  -15.924 -15.845 1   25.515 ? 259  TYR B O   1 
ATOM   6084 C  CB  . TYR B 1 267 ? 24.32   -15.495 -17.857 1   22.061 ? 259  TYR B CB  1 
ATOM   6085 C  CG  . TYR B 1 267 ? 25.08   -15.579 -19.171 1   24.494 ? 259  TYR B CG  1 
ATOM   6086 C  CD1 . TYR B 1 267 ? 24.45   -15.299 -20.38  1   26.166 ? 259  TYR B CD1 1 
ATOM   6087 C  CD2 . TYR B 1 267 ? 26.422  -15.973 -19.185 1   24.547 ? 259  TYR B CD2 1 
ATOM   6088 C  CE1 . TYR B 1 267 ? 25.152  -15.36  -21.576 1   27.988 ? 259  TYR B CE1 1 
ATOM   6089 C  CE2 . TYR B 1 267 ? 27.126  -16.04  -20.377 1   27.258 ? 259  TYR B CE2 1 
ATOM   6090 C  CZ  . TYR B 1 267 ? 26.482  -15.739 -21.561 1   29.733 ? 259  TYR B CZ  1 
ATOM   6091 O  OH  . TYR B 1 267 ? 27.185  -15.803 -22.726 1   32.365 ? 259  TYR B OH  1 
ATOM   6092 N  N   . LEU B 1 268 ? 23.933  -16.845 -15.108 1   23.311 ? 260  LEU B N   1 
ATOM   6093 C  CA  . LEU B 1 268 ? 23.911  -16.184 -13.808 1   21.082 ? 260  LEU B CA  1 
ATOM   6094 C  C   . LEU B 1 268 ? 25.113  -15.262 -13.777 1   21.966 ? 260  LEU B C   1 
ATOM   6095 O  O   . LEU B 1 268 ? 26.236  -15.691 -14.09  1   22.805 ? 260  LEU B O   1 
ATOM   6096 C  CB  . LEU B 1 268 ? 24.004  -17.212 -12.673 1   22.506 ? 260  LEU B CB  1 
ATOM   6097 C  CG  . LEU B 1 268 ? 23.933  -16.602 -11.249 1   21.231 ? 260  LEU B CG  1 
ATOM   6098 C  CD1 . LEU B 1 268 ? 22.591  -15.921 -11.04  1   20.133 ? 260  LEU B CD1 1 
ATOM   6099 C  CD2 . LEU B 1 268 ? 24.186  -17.634 -10.151 1   23.676 ? 260  LEU B CD2 1 
ATOM   6100 N  N   . VAL B 1 269 ? 24.885  -14.004 -13.404 1   20.985 ? 261  VAL B N   1 
ATOM   6101 C  CA  . VAL B 1 269 ? 25.953  -13.023 -13.429 1   22.554 ? 261  VAL B CA  1 
ATOM   6102 C  C   . VAL B 1 269 ? 26.213  -12.574 -11.996 1   20.72  ? 261  VAL B C   1 
ATOM   6103 O  O   . VAL B 1 269 ? 25.345  -11.947 -11.395 1   21.01  ? 261  VAL B O   1 
ATOM   6104 C  CB  . VAL B 1 269 ? 25.635  -11.832 -14.364 1   21.32  ? 261  VAL B CB  1 
ATOM   6105 C  CG1 . VAL B 1 269 ? 26.854  -10.935 -14.555 1   20.474 ? 261  VAL B CG1 1 
ATOM   6106 C  CG2 . VAL B 1 269 ? 25.112  -12.311 -15.734 1   22.291 ? 261  VAL B CG2 1 
ATOM   6107 N  N   . LEU B 1 270 ? 27.447  -12.809 -11.515 1   21.339 ? 262  LEU B N   1 
ATOM   6108 C  CA  . LEU B 1 270 ? 27.788  -12.441 -10.141 1   19.855 ? 262  LEU B CA  1 
ATOM   6109 C  C   . LEU B 1 270 ? 28.338  -11.024 -10.127 1   21.365 ? 262  LEU B C   1 
ATOM   6110 O  O   . LEU B 1 270 ? 29.093  -10.658 -11.019 1   20.874 ? 262  LEU B O   1 
ATOM   6111 C  CB  . LEU B 1 270 ? 28.848  -13.391 -9.601  1   19.721 ? 262  LEU B CB  1 
ATOM   6112 C  CG  . LEU B 1 270 ? 28.501  -14.884 -9.627  1   24.794 ? 262  LEU B CG  1 
ATOM   6113 C  CD1 . LEU B 1 270 ? 29.546  -15.667 -8.823  1   23.623 ? 262  LEU B CD1 1 
ATOM   6114 C  CD2 . LEU B 1 270 ? 27.111  -15.152 -9.125  1   21.646 ? 262  LEU B CD2 1 
ATOM   6115 N  N   . MET B 1 271 ? 28.009  -10.266 -9.069  1   19.814 ? 263  MET B N   1 
ATOM   6116 C  CA  . MET B 1 271 ? 28.406  -8.864  -9.013  1   19.112 ? 263  MET B CA  1 
ATOM   6117 C  C   . MET B 1 271 ? 29.398  -8.714  -7.87   1   20.694 ? 263  MET B C   1 
ATOM   6118 O  O   . MET B 1 271 ? 29.01   -8.892  -6.706  1   20.039 ? 263  MET B O   1 
ATOM   6119 C  CB  . MET B 1 271 ? 27.161  -7.97   -8.882  1   18.334 ? 263  MET B CB  1 
ATOM   6120 C  CG  . MET B 1 271 ? 27.402  -6.461  -8.852  1   20.567 ? 263  MET B CG  1 
ATOM   6121 S  SD  . MET B 1 271 ? 25.825  -5.578  -8.958  1   23.341 ? 263  MET B SD  1 
ATOM   6122 C  CE  . MET B 1 271 ? 24.97   -5.941  -7.405  1   23.313 ? 263  MET B CE  1 
ATOM   6123 N  N   . LEU B 1 272 ? 30.655  -8.361  -8.204  1   20.57  ? 264  LEU B N   1 
ATOM   6124 C  CA  . LEU B 1 272 ? 31.68   -8.283  -7.164  1   20.272 ? 264  LEU B CA  1 
ATOM   6125 C  C   . LEU B 1 272 ? 31.805  -6.838  -6.693  1   20.5   ? 264  LEU B C   1 
ATOM   6126 O  O   . LEU B 1 272 ? 32.143  -5.97   -7.483  1   23.293 ? 264  LEU B O   1 
ATOM   6127 C  CB  . LEU B 1 272 ? 33.049  -8.797  -7.616  1   18.752 ? 264  LEU B CB  1 
ATOM   6128 C  CG  . LEU B 1 272 ? 33.217  -10.315 -7.741  1   21.52  ? 264  LEU B CG  1 
ATOM   6129 C  CD1 . LEU B 1 272 ? 32.201  -11.005 -8.664  1   24.352 ? 264  LEU B CD1 1 
ATOM   6130 C  CD2 . LEU B 1 272 ? 34.655  -10.6   -8.208  1   23.392 ? 264  LEU B CD2 1 
ATOM   6131 N  N   . TRP B 1 273 ? 31.669  -6.635  -5.366  1   18.147 ? 265  TRP B N   1 
ATOM   6132 C  CA  . TRP B 1 273 ? 32.003  -5.374  -4.732  1   20.7   ? 265  TRP B CA  1 
ATOM   6133 C  C   . TRP B 1 273 ? 33.507  -5.302  -4.488  1   19.933 ? 265  TRP B C   1 
ATOM   6134 O  O   . TRP B 1 273 ? 34.148  -6.324  -4.28   1   21.142 ? 265  TRP B O   1 
ATOM   6135 C  CB  . TRP B 1 273 ? 31.302  -5.279  -3.372  1   18.031 ? 265  TRP B CB  1 
ATOM   6136 C  CG  . TRP B 1 273 ? 29.804  -5.201  -3.469  1   17.348 ? 265  TRP B CG  1 
ATOM   6137 C  CD1 . TRP B 1 273 ? 28.982  -5.078  -4.554  1   19.089 ? 265  TRP B CD1 1 
ATOM   6138 C  CD2 . TRP B 1 273 ? 28.952  -5.202  -2.314  1   19.528 ? 265  TRP B CD2 1 
ATOM   6139 N  NE1 . TRP B 1 273 ? 27.676  -5.036  -4.156  1   20.736 ? 265  TRP B NE1 1 
ATOM   6140 C  CE2 . TRP B 1 273 ? 27.621  -5.079  -2.782  1   20.433 ? 265  TRP B CE2 1 
ATOM   6141 C  CE3 . TRP B 1 273 ? 29.204  -5.275  -0.937  1   21.014 ? 265  TRP B CE3 1 
ATOM   6142 C  CZ2 . TRP B 1 273 ? 26.532  -5.059  -1.903  1   19.734 ? 265  TRP B CZ2 1 
ATOM   6143 C  CZ3 . TRP B 1 273 ? 28.128  -5.202  -0.069  1   20.786 ? 265  TRP B CZ3 1 
ATOM   6144 C  CH2 . TRP B 1 273 ? 26.819  -5.082  -0.544  1   21.03  ? 265  TRP B CH2 1 
ATOM   6145 N  N   . PRO B 1 274 ? 34.094  -4.087  -4.475  1   20.927 ? 266  PRO B N   1 
ATOM   6146 C  CA  . PRO B 1 274 ? 35.53   -3.923  -4.292  1   21.467 ? 266  PRO B CA  1 
ATOM   6147 C  C   . PRO B 1 274 ? 35.951  -3.986  -2.825  1   21.525 ? 266  PRO B C   1 
ATOM   6148 O  O   . PRO B 1 274 ? 36.565  -3.052  -2.293  1   21.727 ? 266  PRO B O   1 
ATOM   6149 C  CB  . PRO B 1 274 ? 35.78   -2.542  -4.944  1   21.806 ? 266  PRO B CB  1 
ATOM   6150 C  CG  . PRO B 1 274 ? 34.519  -1.786  -4.57   1   24.085 ? 266  PRO B CG  1 
ATOM   6151 C  CD  . PRO B 1 274 ? 33.409  -2.813  -4.764  1   23.811 ? 266  PRO B CD  1 
ATOM   6152 N  N   . PHE B 1 275 ? 35.58   -5.088  -2.169  1   19.439 ? 267  PHE B N   1 
ATOM   6153 C  CA  . PHE B 1 275 ? 36.121  -5.381  -0.85   1   19.849 ? 267  PHE B CA  1 
ATOM   6154 C  C   . PHE B 1 275 ? 36.895  -6.674  -1.007  1   19.607 ? 267  PHE B C   1 
ATOM   6155 O  O   . PHE B 1 275 ? 36.543  -7.507  -1.837  1   21.243 ? 267  PHE B O   1 
ATOM   6156 C  CB  . PHE B 1 275 ? 35.031  -5.658  0.202   1   19.955 ? 267  PHE B CB  1 
ATOM   6157 C  CG  . PHE B 1 275 ? 34.146  -4.452  0.468   1   22.516 ? 267  PHE B CG  1 
ATOM   6158 C  CD1 . PHE B 1 275 ? 33.069  -4.155  -0.375  1   21.013 ? 267  PHE B CD1 1 
ATOM   6159 C  CD2 . PHE B 1 275 ? 34.353  -3.679  1.621   1   20.338 ? 267  PHE B CD2 1 
ATOM   6160 C  CE1 . PHE B 1 275 ? 32.231  -3.062  -0.098  1   18.848 ? 267  PHE B CE1 1 
ATOM   6161 C  CE2 . PHE B 1 275 ? 33.544  -2.576  1.885   1   20.518 ? 267  PHE B CE2 1 
ATOM   6162 C  CZ  . PHE B 1 275 ? 32.444  -2.303  1.048   1   20.834 ? 267  PHE B CZ  1 
ATOM   6163 N  N   . GLU B 1 276 ? 37.933  -6.84   -0.179  1   19.405 ? 268  GLU B N   1 
ATOM   6164 C  CA  . GLU B 1 276 ? 38.696  -8.073  -0.185  1   18.964 ? 268  GLU B CA  1 
ATOM   6165 C  C   . GLU B 1 276 ? 38.772  -8.584  1.235   1   18.733 ? 268  GLU B C   1 
ATOM   6166 O  O   . GLU B 1 276 ? 38.854  -7.799  2.181   1   20.066 ? 268  GLU B O   1 
ATOM   6167 C  CB  . GLU B 1 276 ? 40.072  -7.819  -0.818  1   20.015 ? 268  GLU B CB  1 
ATOM   6168 C  CG  . GLU B 1 276 ? 40.951  -9.074  -0.882  1   23.807 ? 268  GLU B CG  1 
ATOM   6169 C  CD  . GLU B 1 276 ? 42.13   -8.966  -1.852  1   31.092 ? 268  GLU B CD  1 
ATOM   6170 O  OE1 . GLU B 1 276 ? 42.529  -7.834  -2.198  1   28.362 ? 268  GLU B OE1 1 
ATOM   6171 O  OE2 . GLU B 1 276 ? 42.686  -10.033 -2.227  1   30.523 ? 268  GLU B OE2 1 
ATOM   6172 N  N   . ALA B 1 277 ? 38.706  -9.916  1.362   1   19.994 ? 269  ALA B N   1 
ATOM   6173 C  CA  . ALA B 1 277 ? 38.819  -10.572 2.666   1   19.837 ? 269  ALA B CA  1 
ATOM   6174 C  C   . ALA B 1 277 ? 40.274  -10.992 2.872   1   23.959 ? 269  ALA B C   1 
ATOM   6175 O  O   . ALA B 1 277 ? 40.917  -11.399 1.909   1   24.961 ? 269  ALA B O   1 
ATOM   6176 C  CB  . ALA B 1 277 ? 37.963  -11.818 2.68    1   21.429 ? 269  ALA B CB  1 
ATOM   6177 N  N   . ASN B 1 278 ? 40.753  -10.958 4.116   1   20.005 ? 270  ASN B N   1 
ATOM   6178 C  CA  . ASN B 1 278 ? 42.165  -11.266 4.387   1   22.219 ? 270  ASN B CA  1 
ATOM   6179 C  C   . ASN B 1 278 ? 42.199  -12.047 5.7     1   19.666 ? 270  ASN B C   1 
ATOM   6180 O  O   . ASN B 1 278 ? 41.781  -11.499 6.717   1   22.273 ? 270  ASN B O   1 
ATOM   6181 C  CB  . ASN B 1 278 ? 42.956  -9.958  4.501   1   22.575 ? 270  ASN B CB  1 
ATOM   6182 C  CG  . ASN B 1 278 ? 44.426  -10.23  4.73    1   25.461 ? 270  ASN B CG  1 
ATOM   6183 O  OD1 . ASN B 1 278 ? 44.83   -10.581 5.844   1   23.847 ? 270  ASN B OD1 1 
ATOM   6184 N  ND2 . ASN B 1 278 ? 45.202  -10.233 3.656   1   27.961 ? 270  ASN B ND2 1 
ATOM   6185 N  N   . LEU B 1 279 ? 42.63   -13.33  5.632   1   21.475 ? 271  LEU B N   1 
ATOM   6186 C  CA  . LEU B 1 279 ? 42.653  -14.232 6.78    1   22.872 ? 271  LEU B CA  1 
ATOM   6187 C  C   . LEU B 1 279 ? 43.53   -13.683 7.909   1   22.524 ? 271  LEU B C   1 
ATOM   6188 O  O   . LEU B 1 279 ? 43.145  -13.721 9.085   1   22.307 ? 271  LEU B O   1 
ATOM   6189 C  CB  . LEU B 1 279 ? 43.055  -15.666 6.398   1   23.318 ? 271  LEU B CB  1 
ATOM   6190 C  CG  . LEU B 1 279 ? 42.797  -16.713 7.491   1   25.306 ? 271  LEU B CG  1 
ATOM   6191 C  CD1 . LEU B 1 279 ? 41.285  -16.87  7.829   1   24.431 ? 271  LEU B CD1 1 
ATOM   6192 C  CD2 . LEU B 1 279 ? 43.39   -18.046 7.041   1   26.987 ? 271  LEU B CD2 1 
ATOM   6193 N  N   . GLU B 1 280 ? 44.71   -13.144 7.548   1   23.113 ? 272  GLU B N   1 
ATOM   6194 C  CA  . GLU B 1 280 ? 45.655  -12.636 8.542   1   24.608 ? 272  GLU B CA  1 
ATOM   6195 C  C   . GLU B 1 280 ? 45.06   -11.45  9.304   1   24.364 ? 272  GLU B C   1 
ATOM   6196 O  O   . GLU B 1 280 ? 45.214  -11.367 10.526  1   24.439 ? 272  GLU B O   1 
ATOM   6197 C  CB  . GLU B 1 280 ? 47.001  -12.405 7.836   1   32.365 ? 272  GLU B CB  1 
ATOM   6198 C  CG  . GLU B 1 280 ? 48.032  -11.636 8.665   1   42.361 ? 272  GLU B CG  1 
ATOM   6199 C  CD  . GLU B 1 280 ? 49.244  -11.081 7.91    1   53.669 ? 272  GLU B CD  1 
ATOM   6200 O  OE1 . GLU B 1 280 ? 49.303  -11.108 6.653   1   58.699 ? 272  GLU B OE1 1 
ATOM   6201 O  OE2 . GLU B 1 280 ? 50.153  -10.588 8.613   1   55.391 ? 272  GLU B OE2 1 
ATOM   6202 N  N   . ARG B 1 281 ? 44.357  -10.564 8.58    1   21.445 ? 273  ARG B N   1 
ATOM   6203 C  CA  . ARG B 1 281 ? 43.66   -9.445  9.215   1   21.699 ? 273  ARG B CA  1 
ATOM   6204 C  C   . ARG B 1 281 ? 42.583  -9.959  10.182  1   21.735 ? 273  ARG B C   1 
ATOM   6205 O  O   . ARG B 1 281 ? 42.464  -9.453  11.301  1   21.862 ? 273  ARG B O   1 
ATOM   6206 C  CB  . ARG B 1 281 ? 42.995  -8.48   8.233   1   21.565 ? 273  ARG B CB  1 
ATOM   6207 C  CG  . ARG B 1 281 ? 42.24   -7.31   8.87    1   23.625 ? 273  ARG B CG  1 
ATOM   6208 C  CD  . ARG B 1 281 ? 41.729  -6.296  7.867   1   23.258 ? 273  ARG B CD  1 
ATOM   6209 N  NE  . ARG B 1 281 ? 40.829  -6.973  6.91    1   21.352 ? 273  ARG B NE  1 
ATOM   6210 C  CZ  . ARG B 1 281 ? 40.994  -7.037  5.608   1   23.034 ? 273  ARG B CZ  1 
ATOM   6211 N  NH1 . ARG B 1 281 ? 42.045  -6.473  5.039   1   24.773 ? 273  ARG B NH1 1 
ATOM   6212 N  NH2 . ARG B 1 281 ? 40.131  -7.702  4.88    1   23.616 ? 273  ARG B NH2 1 
ATOM   6213 N  N   . MET B 1 282 ? 41.814  -10.98  9.76    1   21.407 ? 274  MET B N   1 
ATOM   6214 C  CA  . MET B 1 282 ? 40.803  -11.517 10.669  1   19.486 ? 274  MET B CA  1 
ATOM   6215 C  C   . MET B 1 282 ? 41.472  -12.082 11.924  1   19.875 ? 274  MET B C   1 
ATOM   6216 O  O   . MET B 1 282 ? 40.983  -11.866 13.032  1   21.615 ? 274  MET B O   1 
ATOM   6217 C  CB  . MET B 1 282 ? 39.967  -12.594 9.964   1   21.496 ? 274  MET B CB  1 
ATOM   6218 C  CG  . MET B 1 282 ? 39.045  -11.917 8.917   1   23.298 ? 274  MET B CG  1 
ATOM   6219 S  SD  . MET B 1 282 ? 38.129  -13.246 8.109   1   26.385 ? 274  MET B SD  1 
ATOM   6220 C  CE  . MET B 1 282 ? 38.507  -13.129 6.354   1   21.21  ? 274  MET B CE  1 
ATOM   6221 N  N   . LYS B 1 283 ? 42.565  -12.842 11.733  1   22.126 ? 275  LYS B N   1 
ATOM   6222 C  CA  . LYS B 1 283 ? 43.212  -13.481 12.869  1   21.941 ? 275  LYS B CA  1 
ATOM   6223 C  C   . LYS B 1 283 ? 43.709  -12.426 13.855  1   23.753 ? 275  LYS B C   1 
ATOM   6224 O  O   . LYS B 1 283 ? 43.673  -12.662 15.058  1   21.934 ? 275  LYS B O   1 
ATOM   6225 C  CB  . LYS B 1 283 ? 44.351  -14.393 12.397  1   22.831 ? 275  LYS B CB  1 
ATOM   6226 C  CG  . LYS B 1 283 ? 43.88   -15.713 11.797  1   23.048 ? 275  LYS B CG  1 
ATOM   6227 C  CD  . LYS B 1 283 ? 45.093  -16.517 11.316  1   24.494 ? 275  LYS B CD  1 
ATOM   6228 C  CE  . LYS B 1 283 ? 44.703  -17.933 10.976  1   25.356 ? 275  LYS B CE  1 
ATOM   6229 N  NZ  . LYS B 1 283 ? 45.858  -18.571 10.324  1   32.045 ? 275  LYS B NZ  1 
ATOM   6230 N  N   . ALA B 1 284 ? 44.061  -11.25  13.339  1   22.835 ? 276  ALA B N   1 
ATOM   6231 C  CA  . ALA B 1 284 ? 44.508  -10.124 14.147  1   22.307 ? 276  ALA B CA  1 
ATOM   6232 C  C   . ALA B 1 284 ? 43.349  -9.347  14.772  1   25.813 ? 276  ALA B C   1 
ATOM   6233 O  O   . ALA B 1 284 ? 43.58   -8.337  15.428  1   22.817 ? 276  ALA B O   1 
ATOM   6234 C  CB  . ALA B 1 284 ? 45.354  -9.234  13.242  1   23.82  ? 276  ALA B CB  1 
ATOM   6235 N  N   . GLY B 1 285 ? 42.094  -9.779  14.533  1   21.987 ? 277  GLY B N   1 
ATOM   6236 C  CA  . GLY B 1 285 ? 40.972  -9.158  15.215  1   21.879 ? 277  GLY B CA  1 
ATOM   6237 C  C   . GLY B 1 285 ? 40.383  -7.998  14.428  1   22.319 ? 277  GLY B C   1 
ATOM   6238 O  O   . GLY B 1 285 ? 39.653  -7.201  14.994  1   23.809 ? 277  GLY B O   1 
ATOM   6239 N  N   . GLY B 1 286 ? 40.756  -7.889  13.142  1   22.425 ? 278  GLY B N   1 
ATOM   6240 C  CA  . GLY B 1 286 ? 40.291  -6.842  12.252  1   21.292 ? 278  GLY B CA  1 
ATOM   6241 C  C   . GLY B 1 286 ? 39.045  -7.338  11.515  1   22.769 ? 278  GLY B C   1 
ATOM   6242 O  O   . GLY B 1 286 ? 38.598  -8.475  11.676  1   22.613 ? 278  GLY B O   1 
ATOM   6243 N  N   . HIS B 1 287 ? 38.49   -6.46   10.681  1   23.628 ? 279  HIS B N   1 
ATOM   6244 C  CA  . HIS B 1 287 ? 37.293  -6.806  9.928   1   23.224 ? 279  HIS B CA  1 
ATOM   6245 C  C   . HIS B 1 287 ? 37.567  -7.862  8.864   1   24.267 ? 279  HIS B C   1 
ATOM   6246 O  O   . HIS B 1 287 ? 38.659  -8.006  8.31    1   21.923 ? 279  HIS B O   1 
ATOM   6247 C  CB  . HIS B 1 287 ? 36.686  -5.54   9.345   1   22.31  ? 279  HIS B CB  1 
ATOM   6248 C  CG  . HIS B 1 287 ? 35.8    -4.857  10.32   1   25.847 ? 279  HIS B CG  1 
ATOM   6249 N  ND1 . HIS B 1 287 ? 35.954  -3.531  10.652  1   29.734 ? 279  HIS B ND1 1 
ATOM   6250 C  CD2 . HIS B 1 287 ? 34.747  -5.31   11.02   1   23.683 ? 279  HIS B CD2 1 
ATOM   6251 C  CE1 . HIS B 1 287 ? 34.979  -3.192  11.484  1   25.785 ? 279  HIS B CE1 1 
ATOM   6252 N  NE2 . HIS B 1 287 ? 34.27   -4.271  11.756  1   31.979 ? 279  HIS B NE2 1 
ATOM   6253 N  N   . HIS B 1 288 ? 36.484  -8.587  8.548   1   21.735 ? 280  HIS B N   1 
ATOM   6254 C  CA  . HIS B 1 288 ? 36.504  -9.548  7.466   1   20.507 ? 280  HIS B CA  1 
ATOM   6255 C  C   . HIS B 1 288 ? 36.887  -8.864  6.148   1   18.649 ? 280  HIS B C   1 
ATOM   6256 O  O   . HIS B 1 288 ? 37.801  -9.308  5.452   1   20.143 ? 280  HIS B O   1 
ATOM   6257 C  CB  . HIS B 1 288 ? 35.131  -10.223 7.381   1   19.098 ? 280  HIS B CB  1 
ATOM   6258 C  CG  . HIS B 1 288 ? 35.111  -11.382 6.417   1   19.702 ? 280  HIS B CG  1 
ATOM   6259 N  ND1 . HIS B 1 288 ? 35.01   -12.687 6.856   1   18.264 ? 280  HIS B ND1 1 
ATOM   6260 C  CD2 . HIS B 1 288 ? 35.138  -11.426 5.064   1   20.215 ? 280  HIS B CD2 1 
ATOM   6261 C  CE1 . HIS B 1 288 ? 34.925  -13.489 5.787   1   17.665 ? 280  HIS B CE1 1 
ATOM   6262 N  NE2 . HIS B 1 288 ? 35.035  -12.737 4.702   1   18.258 ? 280  HIS B NE2 1 
ATOM   6263 N  N   . TRP B 1 289 ? 36.232  -7.745  5.86    1   17.806 ? 281  TRP B N   1 
ATOM   6264 C  CA  . TRP B 1 289 ? 36.306  -7.054  4.59    1   18.087 ? 281  TRP B CA  1 
ATOM   6265 C  C   . TRP B 1 289 ? 37.043  -5.733  4.778   1   21.942 ? 281  TRP B C   1 
ATOM   6266 O  O   . TRP B 1 289 ? 36.908  -5.097  5.82    1   22.661 ? 281  TRP B O   1 
ATOM   6267 C  CB  . TRP B 1 289 ? 34.877  -6.691  4.116   1   17.533 ? 281  TRP B CB  1 
ATOM   6268 C  CG  . TRP B 1 289 ? 34.054  -7.897  3.799   1   19.204 ? 281  TRP B CG  1 
ATOM   6269 C  CD1 . TRP B 1 289 ? 32.908  -8.296  4.428   1   20.492 ? 281  TRP B CD1 1 
ATOM   6270 C  CD2 . TRP B 1 289 ? 34.316  -8.849  2.745   1   18.835 ? 281  TRP B CD2 1 
ATOM   6271 N  NE1 . TRP B 1 289 ? 32.411  -9.43   3.837   1   19.388 ? 281  TRP B NE1 1 
ATOM   6272 C  CE2 . TRP B 1 289 ? 33.254  -9.799  2.806   1   21.411 ? 281  TRP B CE2 1 
ATOM   6273 C  CE3 . TRP B 1 289 ? 35.324  -8.993  1.771   1   20.852 ? 281  TRP B CE3 1 
ATOM   6274 C  CZ2 . TRP B 1 289 ? 33.236  -10.904 1.951   1   19.008 ? 281  TRP B CZ2 1 
ATOM   6275 C  CZ3 . TRP B 1 289 ? 35.282  -10.052 0.89    1   19.417 ? 281  TRP B CZ3 1 
ATOM   6276 C  CH2 . TRP B 1 289 ? 34.253  -11.019 1.004   1   21.317 ? 281  TRP B CH2 1 
ATOM   6277 N  N   . ALA B 1 290 ? 37.747  -5.31   3.717   1   20.828 ? 282  ALA B N   1 
ATOM   6278 C  CA  . ALA B 1 290 ? 38.294  -3.957  3.655   1   20.931 ? 282  ALA B CA  1 
ATOM   6279 C  C   . ALA B 1 290 ? 38.035  -3.451  2.244   1   20.366 ? 282  ALA B C   1 
ATOM   6280 O  O   . ALA B 1 290 ? 38.333  -4.148  1.293   1   20.428 ? 282  ALA B O   1 
ATOM   6281 C  CB  . ALA B 1 290 ? 39.777  -3.982  3.995   1   21.772 ? 282  ALA B CB  1 
ATOM   6282 N  N   . TYR B 1 291 ? 37.464  -2.251  2.131   1   20.681 ? 283  TYR B N   1 
ATOM   6283 C  CA  . TYR B 1 291 ? 37.221  -1.668  0.814   1   20.319 ? 283  TYR B CA  1 
ATOM   6284 C  C   . TYR B 1 291 ? 38.569  -1.367  0.138   1   22.725 ? 283  TYR B C   1 
ATOM   6285 O  O   . TYR B 1 291 ? 39.544  -1.011  0.773   1   21.111 ? 283  TYR B O   1 
ATOM   6286 C  CB  . TYR B 1 291 ? 36.455  -0.354  1.01    1   18.633 ? 283  TYR B CB  1 
ATOM   6287 C  CG  . TYR B 1 291 ? 35.953  0.25    -0.293  1   20.781 ? 283  TYR B CG  1 
ATOM   6288 C  CD1 . TYR B 1 291 ? 36.742  1.13    -1.066  1   19.838 ? 283  TYR B CD1 1 
ATOM   6289 C  CD2 . TYR B 1 291 ? 34.674  -0.068  -0.749  1   20.793 ? 283  TYR B CD2 1 
ATOM   6290 C  CE1 . TYR B 1 291 ? 36.246  1.681   -2.242  1   19.391 ? 283  TYR B CE1 1 
ATOM   6291 C  CE2 . TYR B 1 291 ? 34.159  0.508   -1.896  1   20.807 ? 283  TYR B CE2 1 
ATOM   6292 C  CZ  . TYR B 1 291 ? 34.956  1.37    -2.657  1   21.162 ? 283  TYR B CZ  1 
ATOM   6293 O  OH  . TYR B 1 291 ? 34.417  1.878   -3.827  1   21.093 ? 283  TYR B OH  1 
ATOM   6294 N  N   . ASP B 1 292 ? 38.605  -1.564  -1.179  1   22.46  ? 284  ASP B N   1 
ATOM   6295 C  CA  . ASP B 1 292 ? 39.841  -1.331  -1.903  1   23.744 ? 284  ASP B CA  1 
ATOM   6296 C  C   . ASP B 1 292 ? 39.513  -0.464  -3.107  1   22.368 ? 284  ASP B C   1 
ATOM   6297 O  O   . ASP B 1 292 ? 38.931  -0.955  -4.056  1   22.474 ? 284  ASP B O   1 
ATOM   6298 C  CB  . ASP B 1 292 ? 40.546  -2.64   -2.221  1   24.244 ? 284  ASP B CB  1 
ATOM   6299 C  CG  . ASP B 1 292 ? 41.845  -2.49   -3.015  1   23.779 ? 284  ASP B CG  1 
ATOM   6300 O  OD1 . ASP B 1 292 ? 42.193  -1.358  -3.438  1   22.916 ? 284  ASP B OD1 1 
ATOM   6301 O  OD2 . ASP B 1 292 ? 42.474  -3.5    -3.214  1   25.025 ? 284  ASP B OD2 1 
ATOM   6302 N  N   . TYR B 1 293 ? 39.919  0.818   -3.059  1   22.24  ? 285  TYR B N   1 
ATOM   6303 C  CA  . TYR B 1 293 ? 39.69   1.735   -4.176  1   23.304 ? 285  TYR B CA  1 
ATOM   6304 C  C   . TYR B 1 293 ? 40.355  1.3     -5.477  1   25.418 ? 285  TYR B C   1 
ATOM   6305 O  O   . TYR B 1 293 ? 39.973  1.807   -6.534  1   25.452 ? 285  TYR B O   1 
ATOM   6306 C  CB  . TYR B 1 293 ? 40.249  3.121   -3.812  1   23.442 ? 285  TYR B CB  1 
ATOM   6307 C  CG  . TYR B 1 293 ? 39.278  3.832   -2.892  1   22.746 ? 285  TYR B CG  1 
ATOM   6308 C  CD1 . TYR B 1 293 ? 38.182  4.53    -3.406  1   26     ? 285  TYR B CD1 1 
ATOM   6309 C  CD2 . TYR B 1 293 ? 39.459  3.779   -1.496  1   25.535 ? 285  TYR B CD2 1 
ATOM   6310 C  CE1 . TYR B 1 293 ? 37.273  5.156   -2.559  1   26.384 ? 285  TYR B CE1 1 
ATOM   6311 C  CE2 . TYR B 1 293 ? 38.562  4.403   -0.643  1   29.022 ? 285  TYR B CE2 1 
ATOM   6312 C  CZ  . TYR B 1 293 ? 37.474  5.094   -1.186  1   29.382 ? 285  TYR B CZ  1 
ATOM   6313 O  OH  . TYR B 1 293 ? 36.612  5.633   -0.279  1   33.825 ? 285  TYR B OH  1 
ATOM   6314 N  N   . THR B 1 294 ? 41.34   0.384   -5.41   1   25.667 ? 286  THR B N   1 
ATOM   6315 C  CA  . THR B 1 294 ? 42.027  -0.073  -6.622  1   26.523 ? 286  THR B CA  1 
ATOM   6316 C  C   . THR B 1 294 ? 41.282  -1.199  -7.336  1   27.35  ? 286  THR B C   1 
ATOM   6317 O  O   . THR B 1 294 ? 41.638  -1.498  -8.472  1   26.568 ? 286  THR B O   1 
ATOM   6318 C  CB  . THR B 1 294 ? 43.502  -0.43   -6.386  1   27.571 ? 286  THR B CB  1 
ATOM   6319 O  OG1 . THR B 1 294 ? 43.567  -1.702  -5.74   1   26.204 ? 286  THR B OG1 1 
ATOM   6320 C  CG2 . THR B 1 294 ? 44.242  0.671   -5.641  1   27.926 ? 286  THR B CG2 1 
ATOM   6321 N  N   . LYS B 1 295 ? 40.255  -1.791  -6.698  1   23.475 ? 287  LYS B N   1 
ATOM   6322 C  CA  . LYS B 1 295 ? 39.546  -2.888  -7.335  1   24.978 ? 287  LYS B CA  1 
ATOM   6323 C  C   . LYS B 1 295 ? 38.437  -2.338  -8.221  1   22.588 ? 287  LYS B C   1 
ATOM   6324 O  O   . LYS B 1 295 ? 37.68   -1.475  -7.794  1   22.987 ? 287  LYS B O   1 
ATOM   6325 C  CB  . LYS B 1 295 ? 38.935  -3.853  -6.31   1   26.261 ? 287  LYS B CB  1 
ATOM   6326 C  CG  . LYS B 1 295 ? 39.939  -4.625  -5.476  1   27.396 ? 287  LYS B CG  1 
ATOM   6327 C  CD  . LYS B 1 295 ? 40.559  -5.819  -6.182  1   31.359 ? 287  LYS B CD  1 
ATOM   6328 C  CE  . LYS B 1 295 ? 41.425  -6.461  -5.142  1   35.812 ? 287  LYS B CE  1 
ATOM   6329 N  NZ  . LYS B 1 295 ? 42.152  -7.609  -5.658  1   49.267 ? 287  LYS B NZ  1 
ATOM   6330 N  N   . PRO B 1 296 ? 38.317  -2.797  -9.492  1   23.761 ? 288  PRO B N   1 
ATOM   6331 C  CA  . PRO B 1 296 ? 37.214  -2.375  -10.337 1   24.966 ? 288  PRO B CA  1 
ATOM   6332 C  C   . PRO B 1 296 ? 35.986  -3.202  -9.99   1   24.564 ? 288  PRO B C   1 
ATOM   6333 O  O   . PRO B 1 296 ? 36.141  -4.351  -9.55   1   24.371 ? 288  PRO B O   1 
ATOM   6334 C  CB  . PRO B 1 296 ? 37.727  -2.661  -11.748 1   23.163 ? 288  PRO B CB  1 
ATOM   6335 C  CG  . PRO B 1 296 ? 38.573  -3.915  -11.508 1   22.975 ? 288  PRO B CG  1 
ATOM   6336 C  CD  . PRO B 1 296 ? 39.251  -3.724  -10.168 1   24.629 ? 288  PRO B CD  1 
ATOM   6337 N  N   . ILE B 1 297 ? 34.797  -2.618  -10.17  1   21.755 ? 289  ILE B N   1 
ATOM   6338 C  CA  . ILE B 1 297 ? 33.597  -3.428  -10.205 1   21.893 ? 289  ILE B CA  1 
ATOM   6339 C  C   . ILE B 1 297 ? 33.849  -4.559  -11.198 1   22.207 ? 289  ILE B C   1 
ATOM   6340 O  O   . ILE B 1 297 ? 34.274  -4.3    -12.333 1   24.383 ? 289  ILE B O   1 
ATOM   6341 C  CB  . ILE B 1 297 ? 32.367  -2.562  -10.568 1   23.036 ? 289  ILE B CB  1 
ATOM   6342 C  CG1 . ILE B 1 297 ? 32.094  -1.613  -9.414  1   21.003 ? 289  ILE B CG1 1 
ATOM   6343 C  CG2 . ILE B 1 297 ? 31.144  -3.451  -10.893 1   22.057 ? 289  ILE B CG2 1 
ATOM   6344 C  CD1 . ILE B 1 297 ? 31.132  -0.466  -9.72   1   23.274 ? 289  ILE B CD1 1 
ATOM   6345 N  N   . THR B 1 298 ? 33.613  -5.803  -10.749 1   21.941 ? 290  THR B N   1 
ATOM   6346 C  CA  . THR B 1 298 ? 33.87   -6.98   -11.57  1   22.156 ? 290  THR B CA  1 
ATOM   6347 C  C   . THR B 1 298 ? 32.597  -7.829  -11.622 1   21.529 ? 290  THR B C   1 
ATOM   6348 O  O   . THR B 1 298 ? 31.862  -7.909  -10.645 1   21.711 ? 290  THR B O   1 
ATOM   6349 C  CB  . THR B 1 298 ? 35.052  -7.742  -10.956 1   23.656 ? 290  THR B CB  1 
ATOM   6350 O  OG1 . THR B 1 298 ? 36.187  -6.892  -11.082 1   24.461 ? 290  THR B OG1 1 
ATOM   6351 C  CG2 . THR B 1 298 ? 35.429  -9.012  -11.7   1   26.009 ? 290  THR B CG2 1 
ATOM   6352 N  N   . TRP B 1 299 ? 32.326  -8.414  -12.799 1   19.102 ? 291  TRP B N   1 
ATOM   6353 C  CA  . TRP B 1 299 ? 31.217  -9.317  -12.988 1   20.403 ? 291  TRP B CA  1 
ATOM   6354 C  C   . TRP B 1 299 ? 31.773  -10.669 -13.423 1   23.049 ? 291  TRP B C   1 
ATOM   6355 O  O   . TRP B 1 299 ? 32.713  -10.714 -14.225 1   26.06  ? 291  TRP B O   1 
ATOM   6356 C  CB  . TRP B 1 299 ? 30.297  -8.754  -14.087 1   21.021 ? 291  TRP B CB  1 
ATOM   6357 C  CG  . TRP B 1 299 ? 29.775  -7.367  -13.829 1   23.082 ? 291  TRP B CG  1 
ATOM   6358 C  CD1 . TRP B 1 299 ? 30.411  -6.197  -14.128 1   25.198 ? 291  TRP B CD1 1 
ATOM   6359 C  CD2 . TRP B 1 299 ? 28.488  -7.002  -13.271 1   23.249 ? 291  TRP B CD2 1 
ATOM   6360 N  NE1 . TRP B 1 299 ? 29.612  -5.135  -13.789 1   27.51  ? 291  TRP B NE1 1 
ATOM   6361 C  CE2 . TRP B 1 299 ? 28.436  -5.587  -13.264 1   23.902 ? 291  TRP B CE2 1 
ATOM   6362 C  CE3 . TRP B 1 299 ? 27.401  -7.718  -12.748 1   22.282 ? 291  TRP B CE3 1 
ATOM   6363 C  CZ2 . TRP B 1 299 ? 27.34   -4.887  -12.763 1   25.042 ? 291  TRP B CZ2 1 
ATOM   6364 C  CZ3 . TRP B 1 299 ? 26.302  -7.025  -12.272 1   25.727 ? 291  TRP B CZ3 1 
ATOM   6365 C  CH2 . TRP B 1 299 ? 26.265  -5.623  -12.312 1   25.695 ? 291  TRP B CH2 1 
ATOM   6366 N  N   . ILE B 1 300 ? 31.117  -11.744 -12.964 1   21.583 ? 292  ILE B N   1 
ATOM   6367 C  CA  . ILE B 1 300 ? 31.451  -13.109 -13.34  1   19.467 ? 292  ILE B CA  1 
ATOM   6368 C  C   . ILE B 1 300 ? 30.242  -13.655 -14.097 1   19.982 ? 292  ILE B C   1 
ATOM   6369 O  O   . ILE B 1 300 ? 29.165  -13.799 -13.527 1   20.398 ? 292  ILE B O   1 
ATOM   6370 C  CB  . ILE B 1 300 ? 31.834  -13.978 -12.12  1   22.247 ? 292  ILE B CB  1 
ATOM   6371 C  CG1 . ILE B 1 300 ? 33.053  -13.401 -11.368 1   20.837 ? 292  ILE B CG1 1 
ATOM   6372 C  CG2 . ILE B 1 300 ? 32.12   -15.421 -12.565 1   22.393 ? 292  ILE B CG2 1 
ATOM   6373 C  CD1 . ILE B 1 300 ? 33.436  -14.201 -10.11  1   24.227 ? 292  ILE B CD1 1 
ATOM   6374 N  N   . THR B 1 301 ? 30.398  -13.938 -15.413 1   21.699 ? 293  THR B N   1 
ATOM   6375 C  CA  . THR B 1 301 ? 29.297  -14.549 -16.133 1   20.291 ? 293  THR B CA  1 
ATOM   6376 C  C   . THR B 1 301 ? 29.454  -16.065 -16.024 1   22.949 ? 293  THR B C   1 
ATOM   6377 O  O   . THR B 1 301 ? 30.528  -16.609 -16.286 1   24.522 ? 293  THR B O   1 
ATOM   6378 C  CB  . THR B 1 301 ? 29.257  -14.062 -17.599 1   22.999 ? 293  THR B CB  1 
ATOM   6379 O  OG1 . THR B 1 301 ? 30.539  -14.247 -18.198 1   22.424 ? 293  THR B OG1 1 
ATOM   6380 C  CG2 . THR B 1 301 ? 28.851  -12.596 -17.697 1   22.807 ? 293  THR B CG2 1 
ATOM   6381 N  N   . ILE B 1 302 ? 28.371  -16.756 -15.627 1   20.521 ? 294  ILE B N   1 
ATOM   6382 C  CA  . ILE B 1 302 ? 28.35   -18.204 -15.531 1   20.726 ? 294  ILE B CA  1 
ATOM   6383 C  C   . ILE B 1 302 ? 27.263  -18.654 -16.484 1   21.09  ? 294  ILE B C   1 
ATOM   6384 O  O   . ILE B 1 302 ? 26.088  -18.467 -16.216 1   21.524 ? 294  ILE B O   1 
ATOM   6385 C  CB  . ILE B 1 302 ? 28.074  -18.706 -14.095 1   22.157 ? 294  ILE B CB  1 
ATOM   6386 C  CG1 . ILE B 1 302 ? 29.067  -18.117 -13.076 1   20.922 ? 294  ILE B CG1 1 
ATOM   6387 C  CG2 . ILE B 1 302 ? 28.074  -20.236 -14.011 1   21.512 ? 294  ILE B CG2 1 
ATOM   6388 C  CD1 . ILE B 1 302 ? 28.671  -18.386 -11.625 1   23.778 ? 294  ILE B CD1 1 
ATOM   6389 N  N   . PRO B 1 303 ? 27.621  -19.268 -17.63  1   22.201 ? 295  PRO B N   1 
ATOM   6390 C  CA  . PRO B 1 303 ? 26.602  -19.893 -18.474 1   23.965 ? 295  PRO B CA  1 
ATOM   6391 C  C   . PRO B 1 303 ? 25.775  -20.88  -17.659 1   23.327 ? 295  PRO B C   1 
ATOM   6392 O  O   . PRO B 1 303 ? 26.332  -21.721 -16.952 1   24.308 ? 295  PRO B O   1 
ATOM   6393 C  CB  . PRO B 1 303 ? 27.422  -20.594 -19.578 1   22.467 ? 295  PRO B CB  1 
ATOM   6394 C  CG  . PRO B 1 303 ? 28.676  -19.725 -19.624 1   24.696 ? 295  PRO B CG  1 
ATOM   6395 C  CD  . PRO B 1 303 ? 28.989  -19.405 -18.169 1   24.187 ? 295  PRO B CD  1 
ATOM   6396 N  N   . ARG B 1 304 ? 24.448  -20.771 -17.744 1   21.491 ? 296  ARG B N   1 
ATOM   6397 C  CA  . ARG B 1 304 ? 23.6    -21.661 -16.964 1   26.498 ? 296  ARG B CA  1 
ATOM   6398 C  C   . ARG B 1 304 ? 23.793  -23.092 -17.451 1   26.924 ? 296  ARG B C   1 
ATOM   6399 O  O   . ARG B 1 304 ? 23.824  -23.317 -18.654 1   26.688 ? 296  ARG B O   1 
ATOM   6400 C  CB  . ARG B 1 304 ? 22.14   -21.231 -16.998 1   23.709 ? 296  ARG B CB  1 
ATOM   6401 C  CG  . ARG B 1 304 ? 22.032  -19.904 -16.243 1   24.047 ? 296  ARG B CG  1 
ATOM   6402 C  CD  . ARG B 1 304 ? 20.605  -19.374 -16.292 1   23.414 ? 296  ARG B CD  1 
ATOM   6403 N  NE  . ARG B 1 304 ? 19.662  -20.258 -15.602 1   23.158 ? 296  ARG B NE  1 
ATOM   6404 C  CZ  . ARG B 1 304 ? 18.341  -20.078 -15.612 1   22.406 ? 296  ARG B CZ  1 
ATOM   6405 N  NH1 . ARG B 1 304 ? 17.818  -19.017 -16.231 1   23.006 ? 296  ARG B NH1 1 
ATOM   6406 N  NH2 . ARG B 1 304 ? 17.56   -20.956 -14.999 1   25.617 ? 296  ARG B NH2 1 
ATOM   6407 N  N   . GLY B 1 305 ? 23.966  -24.015 -16.504 1   24.485 ? 297  GLY B N   1 
ATOM   6408 C  CA  . GLY B 1 305 ? 24.287  -25.4   -16.825 1   28.412 ? 297  GLY B CA  1 
ATOM   6409 C  C   . GLY B 1 305 ? 25.692  -25.596 -17.413 1   29.04  ? 297  GLY B C   1 
ATOM   6410 O  O   . GLY B 1 305 ? 25.943  -26.627 -18.025 1   28.368 ? 297  GLY B O   1 
ATOM   6411 N  N   . ALA B 1 306 ? 26.621  -24.634 -17.219 1   25.721 ? 298  ALA B N   1 
ATOM   6412 C  CA  . ALA B 1 306 ? 28.007  -24.777 -17.659 1   27.582 ? 298  ALA B CA  1 
ATOM   6413 C  C   . ALA B 1 306 ? 28.592  -26.123 -17.249 1   31.739 ? 298  ALA B C   1 
ATOM   6414 O  O   . ALA B 1 306 ? 28.364  -26.589 -16.134 1   30.292 ? 298  ALA B O   1 
ATOM   6415 C  CB  . ALA B 1 306 ? 28.868  -23.655 -17.128 1   31.327 ? 298  ALA B CB  1 
ATOM   6416 N  N   . LYS B 1 307 ? 29.328  -26.738 -18.177 1   36.238 ? 299  LYS B N   1 
ATOM   6417 C  CA  . LYS B 1 307 ? 29.948  -28.038 -17.929 1   37.507 ? 299  LYS B CA  1 
ATOM   6418 C  C   . LYS B 1 307 ? 31.357  -27.872 -17.363 1   33.445 ? 299  LYS B C   1 
ATOM   6419 O  O   . LYS B 1 307 ? 31.862  -28.775 -16.707 1   34.231 ? 299  LYS B O   1 
ATOM   6420 C  CB  . LYS B 1 307 ? 29.832  -28.94  -19.164 1   39.703 ? 299  LYS B CB  1 
ATOM   6421 C  CG  . LYS B 1 307 ? 28.393  -29.32  -19.548 1   49.107 ? 299  LYS B CG  1 
ATOM   6422 C  CD  . LYS B 1 307 ? 27.558  -29.912 -18.404 1   65.869 ? 299  LYS B CD  1 
ATOM   6423 C  CE  . LYS B 1 307 ? 26.22   -30.52  -18.729 1   68.336 ? 299  LYS B CE  1 
ATOM   6424 N  NZ  . LYS B 1 307 ? 26.393  -31.889 -19.222 1   71.749 ? 299  LYS B NZ  1 
ATOM   6425 N  N   . SER B 1 308 ? 31.931  -26.675 -17.518 1   27.441 ? 300  SER B N   1 
ATOM   6426 C  CA  . SER B 1 308 ? 33.301  -26.428 -17.123 1   32.098 ? 300  SER B CA  1 
ATOM   6427 C  C   . SER B 1 308 ? 33.438  -24.991 -16.652 1   27.242 ? 300  SER B C   1 
ATOM   6428 O  O   . SER B 1 308 ? 32.813  -24.095 -17.21  1   25.043 ? 300  SER B O   1 
ATOM   6429 C  CB  . SER B 1 308 ? 34.235  -26.7   -18.311 1   32.498 ? 300  SER B CB  1 
ATOM   6430 O  OG  . SER B 1 308 ? 35.549  -26.271 -18.003 1   35.829 ? 300  SER B OG  1 
ATOM   6431 N  N   . LYS B 1 309 ? 34.306  -24.792 -15.652 1   27.719 ? 301  LYS B N   1 
ATOM   6432 C  CA  . LYS B 1 309 ? 34.663  -23.456 -15.201 1   28.292 ? 301  LYS B CA  1 
ATOM   6433 C  C   . LYS B 1 309 ? 35.388  -22.67  -16.292 1   27.981 ? 301  LYS B C   1 
ATOM   6434 O  O   . LYS B 1 309 ? 35.489  -21.454 -16.2   1   26.034 ? 301  LYS B O   1 
ATOM   6435 C  CB  . LYS B 1 309 ? 35.427  -23.546 -13.886 1   25.321 ? 301  LYS B CB  1 
ATOM   6436 C  CG  . LYS B 1 309 ? 36.847  -24.1   -14.027 1   27.475 ? 301  LYS B CG  1 
ATOM   6437 C  CD  . LYS B 1 309 ? 37.552  -24.198 -12.69  1   33.104 ? 301  LYS B CD  1 
ATOM   6438 C  CE  . LYS B 1 309 ? 39.002  -24.105 -13.113 1   39.865 ? 301  LYS B CE  1 
ATOM   6439 N  NZ  . LYS B 1 309 ? 39.831  -24.857 -12.189 1   53.194 ? 301  LYS B NZ  1 
ATOM   6440 N  N   . ASP B 1 310 ? 35.839  -23.365 -17.351 1   31.284 ? 302  ASP B N   1 
ATOM   6441 C  CA  . ASP B 1 310 ? 36.457  -22.671 -18.477 1   31.21  ? 302  ASP B CA  1 
ATOM   6442 C  C   . ASP B 1 310 ? 35.445  -21.805 -19.227 1   29.643 ? 302  ASP B C   1 
ATOM   6443 O  O   . ASP B 1 310 ? 35.859  -20.922 -19.974 1   29.047 ? 302  ASP B O   1 
ATOM   6444 C  CB  . ASP B 1 310 ? 37.089  -23.635 -19.471 1   34.049 ? 302  ASP B CB  1 
ATOM   6445 C  CG  . ASP B 1 310 ? 38.235  -24.494 -18.949 1   43.429 ? 302  ASP B CG  1 
ATOM   6446 O  OD1 . ASP B 1 310 ? 38.844  -24.144 -17.911 1   39.396 ? 302  ASP B OD1 1 
ATOM   6447 O  OD2 . ASP B 1 310 ? 38.499  -25.537 -19.593 1   46.233 ? 302  ASP B OD2 1 
ATOM   6448 N  N   . GLU B 1 311 ? 34.138  -22.029 -19.023 1   28.334 ? 303  GLU B N   1 
ATOM   6449 C  CA  . GLU B 1 311 ? 33.099  -21.258 -19.703 1   24.613 ? 303  GLU B CA  1 
ATOM   6450 C  C   . GLU B 1 311 ? 32.814  -19.932 -18.994 1   25.53  ? 303  GLU B C   1 
ATOM   6451 O  O   . GLU B 1 311 ? 32.157  -19.05  -19.541 1   27.652 ? 303  GLU B O   1 
ATOM   6452 C  CB  . GLU B 1 311 ? 31.796  -22.058 -19.718 1   30.667 ? 303  GLU B CB  1 
ATOM   6453 C  CG  . GLU B 1 311 ? 31.864  -23.324 -20.566 1   36.072 ? 303  GLU B CG  1 
ATOM   6454 C  CD  . GLU B 1 311 ? 30.535  -24.062 -20.534 1   35.018 ? 303  GLU B CD  1 
ATOM   6455 O  OE1 . GLU B 1 311 ? 29.444  -23.49  -20.792 1   36.433 ? 303  GLU B OE1 1 
ATOM   6456 O  OE2 . GLU B 1 311 ? 30.607  -25.246 -20.196 1   35.328 ? 303  GLU B OE2 1 
ATOM   6457 N  N   . VAL B 1 312 ? 33.283  -19.809 -17.745 1   24.761 ? 304  VAL B N   1 
ATOM   6458 C  CA  . VAL B 1 312 ? 33.048  -18.636 -16.915 1   25.57  ? 304  VAL B CA  1 
ATOM   6459 C  C   . VAL B 1 312 ? 33.994  -17.513 -17.336 1   26.823 ? 304  VAL B C   1 
ATOM   6460 O  O   . VAL B 1 312 ? 35.189  -17.771 -17.56  1   28.392 ? 304  VAL B O   1 
ATOM   6461 C  CB  . VAL B 1 312 ? 33.299  -19.082 -15.457 1   23.373 ? 304  VAL B CB  1 
ATOM   6462 C  CG1 . VAL B 1 312 ? 33.322  -17.93  -14.478 1   23.75  ? 304  VAL B CG1 1 
ATOM   6463 C  CG2 . VAL B 1 312 ? 32.249  -20.088 -14.988 1   24.762 ? 304  VAL B CG2 1 
ATOM   6464 N  N   . LYS B 1 313 ? 33.492  -16.266 -17.362 1   24.56  ? 305  LYS B N   1 
ATOM   6465 C  CA  . LYS B 1 313 ? 34.314  -15.119 -17.747 1   25.426 ? 305  LYS B CA  1 
ATOM   6466 C  C   . LYS B 1 313 ? 34.194  -13.997 -16.724 1   23.208 ? 305  LYS B C   1 
ATOM   6467 O  O   . LYS B 1 313 ? 33.155  -13.837 -16.094 1   25.505 ? 305  LYS B O   1 
ATOM   6468 C  CB  . LYS B 1 313 ? 33.964  -14.56  -19.136 1   23.891 ? 305  LYS B CB  1 
ATOM   6469 C  CG  . LYS B 1 313 ? 34.202  -15.601 -20.263 1   29.537 ? 305  LYS B CG  1 
ATOM   6470 C  CD  . LYS B 1 313 ? 33.99   -14.989 -21.652 1   41.348 ? 305  LYS B CD  1 
ATOM   6471 C  CE  . LYS B 1 313 ? 34.127  -15.95  -22.814 1   44.419 ? 305  LYS B CE  1 
ATOM   6472 N  NZ  . LYS B 1 313 ? 35.368  -16.719 -22.681 1   47.204 ? 305  LYS B NZ  1 
ATOM   6473 N  N   . TYR B 1 314 ? 35.279  -13.236 -16.574 1   24.047 ? 306  TYR B N   1 
ATOM   6474 C  CA  . TYR B 1 314 ? 35.366  -12.083 -15.703 1   26.896 ? 306  TYR B CA  1 
ATOM   6475 C  C   . TYR B 1 314 ? 35.319  -10.821 -16.56  1   28.308 ? 306  TYR B C   1 
ATOM   6476 O  O   . TYR B 1 314 ? 36.054  -10.716 -17.541 1   29.515 ? 306  TYR B O   1 
ATOM   6477 C  CB  . TYR B 1 314 ? 36.685  -12.051 -14.915 1   25.029 ? 306  TYR B CB  1 
ATOM   6478 C  CG  . TYR B 1 314 ? 37.017  -13.268 -14.057 1   25.958 ? 306  TYR B CG  1 
ATOM   6479 C  CD1 . TYR B 1 314 ? 36.031  -14.151 -13.579 1   24.68  ? 306  TYR B CD1 1 
ATOM   6480 C  CD2 . TYR B 1 314 ? 38.327  -13.463 -13.629 1   24.392 ? 306  TYR B CD2 1 
ATOM   6481 C  CE1 . TYR B 1 314 ? 36.349  -15.243 -12.773 1   26.215 ? 306  TYR B CE1 1 
ATOM   6482 C  CE2 . TYR B 1 314 ? 38.654  -14.541 -12.825 1   25.044 ? 306  TYR B CE2 1 
ATOM   6483 C  CZ  . TYR B 1 314 ? 37.673  -15.427 -12.405 1   25.675 ? 306  TYR B CZ  1 
ATOM   6484 O  OH  . TYR B 1 314 ? 38.05   -16.439 -11.586 1   26.117 ? 306  TYR B OH  1 
ATOM   6485 N  N   . TRP B 1 315 ? 34.485  -9.861  -16.152 1   23.858 ? 307  TRP B N   1 
ATOM   6486 C  CA  . TRP B 1 315 ? 34.318  -8.576  -16.833 1   25.129 ? 307  TRP B CA  1 
ATOM   6487 C  C   . TRP B 1 315 ? 34.6    -7.482  -15.808 1   27.351 ? 307  TRP B C   1 
ATOM   6488 O  O   . TRP B 1 315 ? 34.304  -7.669  -14.623 1   26.537 ? 307  TRP B O   1 
ATOM   6489 C  CB  . TRP B 1 315 ? 32.887  -8.459  -17.401 1   23.379 ? 307  TRP B CB  1 
ATOM   6490 C  CG  . TRP B 1 315 ? 32.487  -9.652  -18.235 1   24.075 ? 307  TRP B CG  1 
ATOM   6491 C  CD1 . TRP B 1 315 ? 32.091  -10.884 -17.789 1   25.269 ? 307  TRP B CD1 1 
ATOM   6492 C  CD2 . TRP B 1 315 ? 32.427  -9.716  -19.679 1   23.066 ? 307  TRP B CD2 1 
ATOM   6493 N  NE1 . TRP B 1 315 ? 31.818  -11.714 -18.846 1   26.791 ? 307  TRP B NE1 1 
ATOM   6494 C  CE2 . TRP B 1 315 ? 32.001  -11.022 -20.013 1   24.463 ? 307  TRP B CE2 1 
ATOM   6495 C  CE3 . TRP B 1 315 ? 32.704  -8.793  -20.703 1   26.352 ? 307  TRP B CE3 1 
ATOM   6496 C  CZ2 . TRP B 1 315 ? 31.854  -11.435 -21.344 1   27.422 ? 307  TRP B CZ2 1 
ATOM   6497 C  CZ3 . TRP B 1 315 ? 32.535  -9.2    -22.017 1   26.432 ? 307  TRP B CZ3 1 
ATOM   6498 C  CH2 . TRP B 1 315 ? 32.135  -10.505 -22.328 1   27.737 ? 307  TRP B CH2 1 
ATOM   6499 N  N   . HIS B 1 316 ? 35.164  -6.349  -16.244 1   25.877 ? 308  HIS B N   1 
ATOM   6500 C  CA  . HIS B 1 316 ? 35.505  -5.335  -15.251 1   22.949 ? 308  HIS B CA  1 
ATOM   6501 C  C   . HIS B 1 316 ? 35.1    -3.961  -15.75  1   25.319 ? 308  HIS B C   1 
ATOM   6502 O  O   . HIS B 1 316 ? 35.097  -3.723  -16.956 1   24.61  ? 308  HIS B O   1 
ATOM   6503 C  CB  . HIS B 1 316 ? 36.986  -5.408  -14.853 1   25.059 ? 308  HIS B CB  1 
ATOM   6504 C  CG  . HIS B 1 316 ? 37.911  -4.948  -15.924 1   29.134 ? 308  HIS B CG  1 
ATOM   6505 N  ND1 . HIS B 1 316 ? 38.228  -5.753  -16.994 1   26.35  ? 308  HIS B ND1 1 
ATOM   6506 C  CD2 . HIS B 1 316 ? 38.521  -3.74   -16.141 1   27.714 ? 308  HIS B CD2 1 
ATOM   6507 C  CE1 . HIS B 1 316 ? 39.046  -5.064  -17.814 1   25.544 ? 308  HIS B CE1 1 
ATOM   6508 N  NE2 . HIS B 1 316 ? 39.22   -3.847  -17.317 1   29.202 ? 308  HIS B NE2 1 
ATOM   6509 N  N   . TRP B 1 317 ? 34.81   -3.066  -14.794 1   24.363 ? 309  TRP B N   1 
ATOM   6510 C  CA  . TRP B 1 317 ? 34.601  -1.67   -15.138 1   23.958 ? 309  TRP B CA  1 
ATOM   6511 C  C   . TRP B 1 317 ? 35.614  -0.836  -14.367 1   25.208 ? 309  TRP B C   1 
ATOM   6512 O  O   . TRP B 1 317 ? 36.804  -0.871  -14.703 1   25.486 ? 309  TRP B O   1 
ATOM   6513 C  CB  . TRP B 1 317 ? 33.13   -1.266  -14.959 1   26.171 ? 309  TRP B CB  1 
ATOM   6514 C  CG  . TRP B 1 317 ? 32.901  0.187   -15.285 1   26.011 ? 309  TRP B CG  1 
ATOM   6515 C  CD1 . TRP B 1 317 ? 33.068  0.77    -16.508 1   23.327 ? 309  TRP B CD1 1 
ATOM   6516 C  CD2 . TRP B 1 317 ? 32.481  1.215   -14.374 1   25.867 ? 309  TRP B CD2 1 
ATOM   6517 N  NE1 . TRP B 1 317 ? 32.821  2.114   -16.423 1   23.533 ? 309  TRP B NE1 1 
ATOM   6518 C  CE2 . TRP B 1 317 ? 32.424  2.419   -15.13  1   26.468 ? 309  TRP B CE2 1 
ATOM   6519 C  CE3 . TRP B 1 317 ? 32.14   1.237   -13.005 1   25.352 ? 309  TRP B CE3 1 
ATOM   6520 C  CZ2 . TRP B 1 317 ? 32.042  3.634   -14.552 1   27.206 ? 309  TRP B CZ2 1 
ATOM   6521 C  CZ3 . TRP B 1 317 ? 31.789  2.449   -12.432 1   27.409 ? 309  TRP B CZ3 1 
ATOM   6522 C  CH2 . TRP B 1 317 ? 31.732  3.628   -13.192 1   29.402 ? 309  TRP B CH2 1 
ATOM   6523 N  N   . LYS B 1 318 ? 35.174  -0.117  -13.322 1   24.517 ? 310  LYS B N   1 
ATOM   6524 C  CA  . LYS B 1 318 ? 36.049  0.766   -12.563 1   20.652 ? 310  LYS B CA  1 
ATOM   6525 C  C   . LYS B 1 318 ? 35.58   0.682   -11.114 1   23.546 ? 310  LYS B C   1 
ATOM   6526 O  O   . LYS B 1 318 ? 34.522  0.084   -10.873 1   22.068 ? 310  LYS B O   1 
ATOM   6527 C  CB  . LYS B 1 318 ? 35.828  2.22    -13.029 1   28.245 ? 310  LYS B CB  1 
ATOM   6528 C  CG  . LYS B 1 318 ? 36.209  2.523   -14.499 1   30.516 ? 310  LYS B CG  1 
ATOM   6529 C  CD  . LYS B 1 318 ? 35.843  3.957   -14.906 1   32.89  ? 310  LYS B CD  1 
ATOM   6530 C  CE  . LYS B 1 318 ? 36.199  4.178   -16.351 1   44.447 ? 310  LYS B CE  1 
ATOM   6531 N  NZ  . LYS B 1 318 ? 35.575  5.353   -16.955 1   42.472 ? 310  LYS B NZ  1 
ATOM   6532 N  N   . ASN B 1 319 ? 36.287  1.345   -10.198 1   24.063 ? 311  ASN B N   1 
ATOM   6533 C  CA  . ASN B 1 319 ? 35.934  1.244   -8.779  1   21.008 ? 311  ASN B CA  1 
ATOM   6534 C  C   . ASN B 1 319 ? 34.571  1.88    -8.491  1   22.879 ? 311  ASN B C   1 
ATOM   6535 O  O   . ASN B 1 319 ? 34.196  2.929   -9.032  1   22.429 ? 311  ASN B O   1 
ATOM   6536 C  CB  . ASN B 1 319 ? 36.991  1.883   -7.896  1   23.395 ? 311  ASN B CB  1 
ATOM   6537 C  CG  . ASN B 1 319 ? 36.683  1.645   -6.437  1   21.907 ? 311  ASN B CG  1 
ATOM   6538 O  OD1 . ASN B 1 319 ? 36.346  2.592   -5.737  1   22.46  ? 311  ASN B OD1 1 
ATOM   6539 N  ND2 . ASN B 1 319 ? 36.82   0.405   -5.968  1   20.98  ? 311  ASN B ND2 1 
ATOM   6540 N  N   . GLY B 1 320 ? 33.821  1.247   -7.579  1   22.246 ? 312  GLY B N   1 
ATOM   6541 C  CA  . GLY B 1 320 ? 32.568  1.773   -7.057  1   21.973 ? 312  GLY B CA  1 
ATOM   6542 C  C   . GLY B 1 320 ? 31.797  0.594   -6.451  1   23.856 ? 312  GLY B C   1 
ATOM   6543 O  O   . GLY B 1 320 ? 32.321  -0.52   -6.448  1   24.194 ? 312  GLY B O   1 
ATOM   6544 N  N   . MET B 1 321 ? 30.568  0.833   -5.984  1   23.534 ? 313  MET B N   1 
ATOM   6545 C  CA  . MET B 1 321 ? 29.852  -0.182  -5.22   1   20.481 ? 313  MET B CA  1 
ATOM   6546 C  C   . MET B 1 321 ? 28.42   -0.252  -5.755  1   20.709 ? 313  MET B C   1 
ATOM   6547 O  O   . MET B 1 321 ? 27.552  0.544   -5.367  1   23.011 ? 313  MET B O   1 
ATOM   6548 C  CB  . MET B 1 321 ? 29.949  0.143   -3.713  1   19.941 ? 313  MET B CB  1 
ATOM   6549 C  CG  . MET B 1 321 ? 29.318  -0.926  -2.847  1   21.827 ? 313  MET B CG  1 
ATOM   6550 S  SD  . MET B 1 321 ? 29.817  -0.545  -1.167  1   23.073 ? 313  MET B SD  1 
ATOM   6551 C  CE  . MET B 1 321 ? 28.619  -1.607  -0.332  1   22.157 ? 313  MET B CE  1 
ATOM   6552 N  N   . PRO B 1 322 ? 28.14   -1.186  -6.692  1   20.997 ? 314  PRO B N   1 
ATOM   6553 C  CA  . PRO B 1 322 ? 26.779  -1.429  -7.145  1   20.996 ? 314  PRO B CA  1 
ATOM   6554 C  C   . PRO B 1 322 ? 26.116  -2.416  -6.176  1   21.181 ? 314  PRO B C   1 
ATOM   6555 O  O   . PRO B 1 322 ? 26.526  -3.592  -6.124  1   22.434 ? 314  PRO B O   1 
ATOM   6556 C  CB  . PRO B 1 322 ? 27.018  -1.987  -8.552  1   21.701 ? 314  PRO B CB  1 
ATOM   6557 C  CG  . PRO B 1 322 ? 28.331  -2.758  -8.411  1   21.4   ? 314  PRO B CG  1 
ATOM   6558 C  CD  . PRO B 1 322 ? 29.102  -2.169  -7.243  1   22.467 ? 314  PRO B CD  1 
ATOM   6559 N  N   . ILE B 1 323 ? 25.154  -1.929  -5.379  1   22.304 ? 315  ILE B N   1 
ATOM   6560 C  CA  . ILE B 1 323 ? 24.802  -2.684  -4.173  1   20.674 ? 315  ILE B CA  1 
ATOM   6561 C  C   . ILE B 1 323 ? 23.856  -3.838  -4.521  1   22.445 ? 315  ILE B C   1 
ATOM   6562 O  O   . ILE B 1 323 ? 24.124  -4.969  -4.112  1   21.787 ? 315  ILE B O   1 
ATOM   6563 C  CB  . ILE B 1 323 ? 24.273  -1.756  -3.064  1   22.635 ? 315  ILE B CB  1 
ATOM   6564 C  CG1 . ILE B 1 323 ? 25.283  -0.69   -2.727  1   21.735 ? 315  ILE B CG1 1 
ATOM   6565 C  CG2 . ILE B 1 323 ? 23.889  -2.558  -1.799  1   21.268 ? 315  ILE B CG2 1 
ATOM   6566 C  CD1 . ILE B 1 323 ? 24.652  0.469   -1.961  1   24.071 ? 315  ILE B CD1 1 
ATOM   6567 N  N   . HIS B 1 324 ? 22.784  -3.529  -5.27   1   20.068 ? 316  HIS B N   1 
ATOM   6568 C  CA  . HIS B 1 324 ? 21.756  -4.502  -5.602  1   20.182 ? 316  HIS B CA  1 
ATOM   6569 C  C   . HIS B 1 324 ? 21.38   -4.35   -7.066  1   20.929 ? 316  HIS B C   1 
ATOM   6570 O  O   . HIS B 1 324 ? 21.292  -3.223  -7.57   1   23.677 ? 316  HIS B O   1 
ATOM   6571 C  CB  . HIS B 1 324 ? 20.489  -4.252  -4.775  1   19.71  ? 316  HIS B CB  1 
ATOM   6572 C  CG  . HIS B 1 324 ? 20.645  -4.735  -3.376  1   20.03  ? 316  HIS B CG  1 
ATOM   6573 N  ND1 . HIS B 1 324 ? 20.603  -3.867  -2.318  1   20.691 ? 316  HIS B ND1 1 
ATOM   6574 C  CD2 . HIS B 1 324 ? 20.797  -5.958  -2.86   1   20.386 ? 316  HIS B CD2 1 
ATOM   6575 C  CE1 . HIS B 1 324 ? 20.747  -4.525  -1.17   1   19.515 ? 316  HIS B CE1 1 
ATOM   6576 N  NE2 . HIS B 1 324 ? 20.904  -5.785  -1.482  1   20.371 ? 316  HIS B NE2 1 
ATOM   6577 N  N   . THR B 1 325 ? 21.071  -5.486  -7.671  1   19.555 ? 317  THR B N   1 
ATOM   6578 C  CA  . THR B 1 325 ? 20.487  -5.474  -8.996  1   19.867 ? 317  THR B CA  1 
ATOM   6579 C  C   . THR B 1 325 ? 18.972  -5.361  -8.856  1   20.906 ? 317  THR B C   1 
ATOM   6580 O  O   . THR B 1 325 ? 18.381  -5.869  -7.89   1   21.606 ? 317  THR B O   1 
ATOM   6581 C  CB  . THR B 1 325 ? 20.909  -6.718  -9.786  1   20.41  ? 317  THR B CB  1 
ATOM   6582 O  OG1 . THR B 1 325 ? 20.397  -7.868  -9.109  1   24.067 ? 317  THR B OG1 1 
ATOM   6583 C  CG2 . THR B 1 325 ? 22.407  -6.793  -9.999  1   20.524 ? 317  THR B CG2 1 
ATOM   6584 N  N   . ALA B 1 326 ? 18.354  -4.735  -9.869  1   20.475 ? 318  ALA B N   1 
ATOM   6585 C  CA  . ALA B 1 326 ? 16.913  -4.853  -10.061 1   19.87  ? 318  ALA B CA  1 
ATOM   6586 C  C   . ALA B 1 326 ? 16.705  -6.246  -10.639 1   20.062 ? 318  ALA B C   1 
ATOM   6587 O  O   . ALA B 1 326 ? 16.3    -7.177  -9.932  1   20.73  ? 318  ALA B O   1 
ATOM   6588 C  CB  . ALA B 1 326 ? 16.439  -3.695  -10.929 1   20.225 ? 318  ALA B CB  1 
ATOM   6589 N  N   . SER B 1 327 ? 17.016  -6.416  -11.935 1   20.61  ? 319  SER B N   1 
ATOM   6590 C  CA  . SER B 1 327 ? 17.225  -7.738  -12.489 1   22.824 ? 319  SER B CA  1 
ATOM   6591 C  C   . SER B 1 327 ? 18.14   -7.616  -13.723 1   21.839 ? 319  SER B C   1 
ATOM   6592 O  O   . SER B 1 327 ? 18.757  -6.553  -13.92  1   22.475 ? 319  SER B O   1 
ATOM   6593 C  CB  . SER B 1 327 ? 15.91   -8.458  -12.77  1   19.713 ? 319  SER B CB  1 
ATOM   6594 O  OG  . SER B 1 327 ? 16.124  -9.859  -12.957 1   20.515 ? 319  SER B OG  1 
ATOM   6595 N  N   . GLY B 1 328 ? 18.221  -8.715  -14.482 1   19.824 ? 320  GLY B N   1 
ATOM   6596 C  CA  . GLY B 1 328 ? 18.895  -8.689  -15.777 1   19.868 ? 320  GLY B CA  1 
ATOM   6597 C  C   . GLY B 1 328 ? 18.076  -9.416  -16.828 1   21.51  ? 320  GLY B C   1 
ATOM   6598 O  O   . GLY B 1 328 ? 17.06   -10.033 -16.533 1   25.395 ? 320  GLY B O   1 
ATOM   6599 N  N   . PHE B 1 329 ? 18.541  -9.322  -18.078 1   19.513 ? 321  PHE B N   1 
ATOM   6600 C  CA  . PHE B 1 329 ? 17.944  -10.079 -19.163 1   22.173 ? 321  PHE B CA  1 
ATOM   6601 C  C   . PHE B 1 329 ? 18.93   -10.056 -20.325 1   22.779 ? 321  PHE B C   1 
ATOM   6602 O  O   . PHE B 1 329 ? 19.955  -9.377  -20.252 1   26.369 ? 321  PHE B O   1 
ATOM   6603 C  CB  . PHE B 1 329 ? 16.557  -9.512  -19.545 1   21.778 ? 321  PHE B CB  1 
ATOM   6604 C  CG  . PHE B 1 329 ? 16.566  -8.119  -20.148 1   24.537 ? 321  PHE B CG  1 
ATOM   6605 C  CD1 . PHE B 1 329 ? 16.533  -6.984  -19.335 1   25.499 ? 321  PHE B CD1 1 
ATOM   6606 C  CD2 . PHE B 1 329 ? 16.563  -7.945  -21.55  1   26.043 ? 321  PHE B CD2 1 
ATOM   6607 C  CE1 . PHE B 1 329 ? 16.543  -5.7    -19.88  1   26.437 ? 321  PHE B CE1 1 
ATOM   6608 C  CE2 . PHE B 1 329 ? 16.568  -6.662  -22.099 1   24.659 ? 321  PHE B CE2 1 
ATOM   6609 C  CZ  . PHE B 1 329 ? 16.561  -5.538  -21.275 1   25.173 ? 321  PHE B CZ  1 
ATOM   6610 N  N   . GLU B 1 330 ? 18.614  -10.866 -21.346 1   24.687 ? 322  GLU B N   1 
ATOM   6611 C  CA  . GLU B 1 330 ? 19.356  -10.83  -22.592 1   24.399 ? 322  GLU B CA  1 
ATOM   6612 C  C   . GLU B 1 330 ? 18.496  -10.137 -23.631 1   24.815 ? 322  GLU B C   1 
ATOM   6613 O  O   . GLU B 1 330 ? 17.33   -10.482 -23.804 1   26.687 ? 322  GLU B O   1 
ATOM   6614 C  CB  . GLU B 1 330 ? 19.84   -12.223 -22.989 1   25.421 ? 322  GLU B CB  1 
ATOM   6615 C  CG  . GLU B 1 330 ? 21.02   -12.706 -22.148 1   25.776 ? 322  GLU B CG  1 
ATOM   6616 C  CD  . GLU B 1 330 ? 21.046  -14.222 -22.207 1   32.411 ? 322  GLU B CD  1 
ATOM   6617 O  OE1 . GLU B 1 330 ? 21.172  -14.774 -23.332 1   34.302 ? 322  GLU B OE1 1 
ATOM   6618 O  OE2 . GLU B 1 330 ? 20.858  -14.869 -21.156 1   29.652 ? 322  GLU B OE2 1 
ATOM   6619 N  N   . ASP B 1 331 ? 19.081  -9.115  -24.249 1   25.483 ? 323  ASP B N   1 
ATOM   6620 C  CA  . ASP B 1 331 ? 18.377  -8.387  -25.288 1   29.798 ? 323  ASP B CA  1 
ATOM   6621 C  C   . ASP B 1 331 ? 18.362  -9.247  -26.558 1   32.75  ? 323  ASP B C   1 
ATOM   6622 O  O   . ASP B 1 331 ? 18.868  -10.369 -26.588 1   28.343 ? 323  ASP B O   1 
ATOM   6623 C  CB  . ASP B 1 331 ? 18.946  -6.988  -25.443 1   27.155 ? 323  ASP B CB  1 
ATOM   6624 C  CG  . ASP B 1 331 ? 20.286  -6.885  -26.164 1   27.682 ? 323  ASP B CG  1 
ATOM   6625 O  OD1 . ASP B 1 331 ? 20.814  -7.916  -26.68  1   30.202 ? 323  ASP B OD1 1 
ATOM   6626 O  OD2 . ASP B 1 331 ? 20.83   -5.781  -26.16  1   31.513 ? 323  ASP B OD2 1 
ATOM   6627 N  N   . GLU B 1 332 ? 17.776  -8.69   -27.628 1   35.54  ? 324  GLU B N   1 
ATOM   6628 C  CA  . GLU B 1 332 ? 17.574  -9.425  -28.881 1   39.206 ? 324  GLU B CA  1 
ATOM   6629 C  C   . GLU B 1 332 ? 18.898  -9.872  -29.506 1   34.758 ? 324  GLU B C   1 
ATOM   6630 O  O   . GLU B 1 332 ? 18.92   -10.858 -30.228 1   38.17  ? 324  GLU B O   1 
ATOM   6631 C  CB  . GLU B 1 332 ? 16.725  -8.639  -29.881 1   37.475 ? 324  GLU B CB  1 
ATOM   6632 C  CG  . GLU B 1 332 ? 15.323  -8.287  -29.37  1   43.418 ? 324  GLU B CG  1 
ATOM   6633 C  CD  . GLU B 1 332 ? 15.184  -6.993  -28.562 1   48.679 ? 324  GLU B CD  1 
ATOM   6634 O  OE1 . GLU B 1 332 ? 16.174  -6.355  -28.037 1   45.95  ? 324  GLU B OE1 1 
ATOM   6635 O  OE2 . GLU B 1 332 ? 13.994  -6.575  -28.5   1   49.679 ? 324  GLU B OE2 1 
ATOM   6636 N  N   . GLN B 1 333 ? 19.987  -9.156  -29.218 1   30.179 ? 325  GLN B N   1 
ATOM   6637 C  CA  . GLN B 1 333 ? 21.338  -9.408  -29.718 1   32.396 ? 325  GLN B CA  1 
ATOM   6638 C  C   . GLN B 1 333 ? 22.143  -10.292 -28.763 1   33.034 ? 325  GLN B C   1 
ATOM   6639 O  O   . GLN B 1 333 ? 23.321  -10.517 -28.993 1   32.876 ? 325  GLN B O   1 
ATOM   6640 C  CB  . GLN B 1 333 ? 22.128  -8.093  -29.795 1   30.215 ? 325  GLN B CB  1 
ATOM   6641 C  CG  . GLN B 1 333 ? 21.574  -7.031  -30.736 1   34.664 ? 325  GLN B CG  1 
ATOM   6642 C  CD  . GLN B 1 333 ? 20.21   -6.459  -30.387 1   35.279 ? 325  GLN B CD  1 
ATOM   6643 O  OE1 . GLN B 1 333 ? 19.244  -6.682  -31.118 1   35.557 ? 325  GLN B OE1 1 
ATOM   6644 N  NE2 . GLN B 1 333 ? 20.109  -5.685  -29.312 1   40.539 ? 325  GLN B NE2 1 
ATOM   6645 N  N   . GLY B 1 334 ? 21.516  -10.74  -27.658 1   32.813 ? 326  GLY B N   1 
ATOM   6646 C  CA  . GLY B 1 334 ? 22.148  -11.628 -26.697 1   30.796 ? 326  GLY B CA  1 
ATOM   6647 C  C   . GLY B 1 334 ? 22.963  -10.853 -25.662 1   28.807 ? 326  GLY B C   1 
ATOM   6648 O  O   . GLY B 1 334 ? 23.675  -11.468 -24.872 1   27.059 ? 326  GLY B O   1 
ATOM   6649 N  N   . ARG B 1 335 ? 22.843  -9.52   -25.636 1   26.713 ? 327  ARG B N   1 
ATOM   6650 C  CA  . ARG B 1 335 ? 23.663  -8.758  -24.691 1   25.642 ? 327  ARG B CA  1 
ATOM   6651 C  C   . ARG B 1 335 ? 22.967  -8.843  -23.322 1   28.457 ? 327  ARG B C   1 
ATOM   6652 O  O   . ARG B 1 335 ? 21.73   -8.849  -23.239 1   28.142 ? 327  ARG B O   1 
ATOM   6653 C  CB  . ARG B 1 335 ? 23.805  -7.274  -25.037 1   28.111 ? 327  ARG B CB  1 
ATOM   6654 C  CG  . ARG B 1 335 ? 24.292  -7.033  -26.474 1   28.011 ? 327  ARG B CG  1 
ATOM   6655 C  CD  . ARG B 1 335 ? 24.557  -5.583  -26.755 1   25.715 ? 327  ARG B CD  1 
ATOM   6656 N  NE  . ARG B 1 335 ? 23.355  -4.737  -26.757 1   28.636 ? 327  ARG B NE  1 
ATOM   6657 C  CZ  . ARG B 1 335 ? 23.354  -3.396  -26.76  1   30.25  ? 327  ARG B CZ  1 
ATOM   6658 N  NH1 . ARG B 1 335 ? 24.48   -2.721  -26.88  1   31.73  ? 327  ARG B NH1 1 
ATOM   6659 N  NH2 . ARG B 1 335 ? 22.216  -2.711  -26.655 1   31.862 ? 327  ARG B NH2 1 
ATOM   6660 N  N   . ILE B 1 336 ? 23.799  -8.925  -22.288 1   23.612 ? 328  ILE B N   1 
ATOM   6661 C  CA  . ILE B 1 336 ? 23.341  -8.977  -20.89  1   24.334 ? 328  ILE B CA  1 
ATOM   6662 C  C   . ILE B 1 336 ? 23.122  -7.547  -20.417 1   24.092 ? 328  ILE B C   1 
ATOM   6663 O  O   . ILE B 1 336 ? 24.046  -6.732  -20.471 1   25.574 ? 328  ILE B O   1 
ATOM   6664 C  CB  . ILE B 1 336 ? 24.348  -9.71   -19.982 1   22.388 ? 328  ILE B CB  1 
ATOM   6665 C  CG1 . ILE B 1 336 ? 24.474  -11.184 -20.376 1   23.362 ? 328  ILE B CG1 1 
ATOM   6666 C  CG2 . ILE B 1 336 ? 23.942  -9.577  -18.494 1   21.663 ? 328  ILE B CG2 1 
ATOM   6667 C  CD1 . ILE B 1 336 ? 25.811  -11.826 -20.031 1   22.222 ? 328  ILE B CD1 1 
ATOM   6668 N  N   . ILE B 1 337 ? 21.87   -7.254  -20.017 1   23.151 ? 329  ILE B N   1 
ATOM   6669 C  CA  . ILE B 1 337 ? 21.492  -5.919  -19.569 1   24.201 ? 329  ILE B CA  1 
ATOM   6670 C  C   . ILE B 1 337 ? 21.121  -6.073  -18.094 1   23.957 ? 329  ILE B C   1 
ATOM   6671 O  O   . ILE B 1 337 ? 20.256  -6.891  -17.795 1   23.959 ? 329  ILE B O   1 
ATOM   6672 C  CB  . ILE B 1 337 ? 20.278  -5.416  -20.372 1   23.442 ? 329  ILE B CB  1 
ATOM   6673 C  CG1 . ILE B 1 337 ? 20.543  -5.431  -21.928 1   24.244 ? 329  ILE B CG1 1 
ATOM   6674 C  CG2 . ILE B 1 337 ? 19.902  -4.005  -19.931 1   22.998 ? 329  ILE B CG2 1 
ATOM   6675 C  CD1 . ILE B 1 337 ? 21.818  -4.72   -22.361 1   26.419 ? 329  ILE B CD1 1 
ATOM   6676 N  N   . ILE B 1 338 ? 21.748  -5.285  -17.224 1   21.843 ? 330  ILE B N   1 
ATOM   6677 C  CA  . ILE B 1 338 ? 21.486  -5.388  -15.787 1   23.287 ? 330  ILE B CA  1 
ATOM   6678 C  C   . ILE B 1 338 ? 21.354  -3.969  -15.251 1   22.74  ? 330  ILE B C   1 
ATOM   6679 O  O   . ILE B 1 338 ? 22.255  -3.158  -15.462 1   23.506 ? 330  ILE B O   1 
ATOM   6680 C  CB  . ILE B 1 338 ? 22.652  -6.119  -15.072 1   23.199 ? 330  ILE B CB  1 
ATOM   6681 C  CG1 . ILE B 1 338 ? 22.821  -7.564  -15.572 1   24.363 ? 330  ILE B CG1 1 
ATOM   6682 C  CG2 . ILE B 1 338 ? 22.446  -6.114  -13.534 1   23.646 ? 330  ILE B CG2 1 
ATOM   6683 C  CD1 . ILE B 1 338 ? 24.16   -8.21   -15.178 1   22.499 ? 330  ILE B CD1 1 
ATOM   6684 N  N   . ASP B 1 339 ? 20.301  -3.707  -14.453 1   20.353 ? 331  ASP B N   1 
ATOM   6685 C  CA  . ASP B 1 339 ? 20.218  -2.424  -13.797 1   21.492 ? 331  ASP B CA  1 
ATOM   6686 C  C   . ASP B 1 339 ? 20.551  -2.637  -12.327 1   21.474 ? 331  ASP B C   1 
ATOM   6687 O  O   . ASP B 1 339 ? 20.192  -3.686  -11.786 1   21.13  ? 331  ASP B O   1 
ATOM   6688 C  CB  . ASP B 1 339 ? 18.845  -1.776  -13.887 1   22.159 ? 331  ASP B CB  1 
ATOM   6689 C  CG  . ASP B 1 339 ? 18.427  -1.283  -15.267 1   31.14  ? 331  ASP B CG  1 
ATOM   6690 O  OD1 . ASP B 1 339 ? 19.102  -1.662  -16.245 1   29.776 ? 331  ASP B OD1 1 
ATOM   6691 O  OD2 . ASP B 1 339 ? 17.429  -0.535  -15.351 1   28.749 ? 331  ASP B OD2 1 
ATOM   6692 N  N   . SER B 1 340 ? 21.268  -1.669  -11.769 1   21.69  ? 332  SER B N   1 
ATOM   6693 C  CA  . SER B 1 340 ? 21.641  -1.753  -10.369 1   21.703 ? 332  SER B CA  1 
ATOM   6694 C  C   . SER B 1 340 ? 21.732  -0.372  -9.757  1   21.988 ? 332  SER B C   1 
ATOM   6695 O  O   . SER B 1 340 ? 21.834  0.64    -10.452 1   22.421 ? 332  SER B O   1 
ATOM   6696 C  CB  . SER B 1 340 ? 22.992  -2.482  -10.221 1   24.149 ? 332  SER B CB  1 
ATOM   6697 O  OG  . SER B 1 340 ? 24.086  -1.6    -10.484 1   23.425 ? 332  SER B OG  1 
ATOM   6698 N  N   . SER B 1 341 ? 21.734  -0.335  -8.402  1   21.011 ? 333  SER B N   1 
ATOM   6699 C  CA  . SER B 1 341 ? 22.228  0.873   -7.77   1   21.449 ? 333  SER B CA  1 
ATOM   6700 C  C   . SER B 1 341 ? 23.732  1.004   -8.02   1   24.677 ? 333  SER B C   1 
ATOM   6701 O  O   . SER B 1 341 ? 24.397  0.044   -8.393  1   25.269 ? 333  SER B O   1 
ATOM   6702 C  CB  . SER B 1 341 ? 21.896  0.865   -6.268  1   23.55  ? 333  SER B CB  1 
ATOM   6703 O  OG  . SER B 1 341 ? 22.512  -0.256  -5.655  1   27.003 ? 333  SER B OG  1 
ATOM   6704 N  N   . LEU B 1 342 ? 24.249  2.227   -7.948  1   21.689 ? 334  LEU B N   1 
ATOM   6705 C  CA  . LEU B 1 342 ? 25.689  2.451   -8.026  1   20.763 ? 334  LEU B CA  1 
ATOM   6706 C  C   . LEU B 1 342 ? 26.022  3.573   -7.079  1   23.01  ? 334  LEU B C   1 
ATOM   6707 O  O   . LEU B 1 342 ? 25.569  4.704   -7.287  1   23.356 ? 334  LEU B O   1 
ATOM   6708 C  CB  . LEU B 1 342 ? 26.164  2.79    -9.446  1   23.799 ? 334  LEU B CB  1 
ATOM   6709 C  CG  . LEU B 1 342 ? 27.659  3.13    -9.587  1   23.797 ? 334  LEU B CG  1 
ATOM   6710 C  CD1 . LEU B 1 342 ? 28.523  1.945   -9.129  1   22.164 ? 334  LEU B CD1 1 
ATOM   6711 C  CD2 . LEU B 1 342 ? 27.935  3.377   -11.086 1   24.858 ? 334  LEU B CD2 1 
ATOM   6712 N  N   . VAL B 1 343 ? 26.838  3.221   -6.088  1   21.832 ? 335  VAL B N   1 
ATOM   6713 C  CA  . VAL B 1 343 ? 27.437  4.189   -5.203  1   20.793 ? 335  VAL B CA  1 
ATOM   6714 C  C   . VAL B 1 343 ? 28.898  4.356   -5.618  1   22.261 ? 335  VAL B C   1 
ATOM   6715 O  O   . VAL B 1 343 ? 29.634  3.366   -5.69   1   20.853 ? 335  VAL B O   1 
ATOM   6716 C  CB  . VAL B 1 343 ? 27.249  3.815   -3.713  1   21.463 ? 335  VAL B CB  1 
ATOM   6717 C  CG1 . VAL B 1 343 ? 27.973  4.814   -2.801  1   19.514 ? 335  VAL B CG1 1 
ATOM   6718 C  CG2 . VAL B 1 343 ? 25.752  3.758   -3.378  1   21.368 ? 335  VAL B CG2 1 
ATOM   6719 N  N   . HIS B 1 344 ? 29.299  5.626   -5.848  1   23.895 ? 336  HIS B N   1 
ATOM   6720 C  CA  . HIS B 1 344 ? 30.617  5.931   -6.406  1   23.276 ? 336  HIS B CA  1 
ATOM   6721 C  C   . HIS B 1 344 ? 31.665  5.985   -5.297  1   24.3   ? 336  HIS B C   1 
ATOM   6722 O  O   . HIS B 1 344 ? 32.326  7.005   -5.111  1   25.634 ? 336  HIS B O   1 
ATOM   6723 C  CB  . HIS B 1 344 ? 30.533  7.239   -7.22   1   24.688 ? 336  HIS B CB  1 
ATOM   6724 C  CG  . HIS B 1 344 ? 29.717  7.053   -8.45   1   28.802 ? 336  HIS B CG  1 
ATOM   6725 N  ND1 . HIS B 1 344 ? 30.327  6.752   -9.65   1   31.681 ? 336  HIS B ND1 1 
ATOM   6726 C  CD2 . HIS B 1 344 ? 28.374  7.094   -8.701  1   26.452 ? 336  HIS B CD2 1 
ATOM   6727 C  CE1 . HIS B 1 344 ? 29.387  6.614   -10.591 1   31.045 ? 336  HIS B CE1 1 
ATOM   6728 N  NE2 . HIS B 1 344 ? 28.206  6.862   -10.043 1   30.966 ? 336  HIS B NE2 1 
ATOM   6729 N  N   . GLY B 1 345 ? 31.803  4.913   -4.524  1   22.929 ? 337  GLY B N   1 
ATOM   6730 C  CA  . GLY B 1 345 ? 32.584  4.953   -3.299  1   23.769 ? 337  GLY B CA  1 
ATOM   6731 C  C   . GLY B 1 345 ? 32.017  3.929   -2.314  1   23.955 ? 337  GLY B C   1 
ATOM   6732 O  O   . GLY B 1 345 ? 31.216  3.071   -2.721  1   21.731 ? 337  GLY B O   1 
ATOM   6733 N  N   . ASN B 1 346 ? 32.437  4.05    -1.051  1   21.885 ? 338  ASN B N   1 
ATOM   6734 C  CA  . ASN B 1 346 ? 32.147  3.014   -0.069  1   25.318 ? 338  ASN B CA  1 
ATOM   6735 C  C   . ASN B 1 346 ? 30.826  3.307   0.662   1   22.685 ? 338  ASN B C   1 
ATOM   6736 O  O   . ASN B 1 346 ? 30.818  4.132   1.573   1   25.391 ? 338  ASN B O   1 
ATOM   6737 C  CB  . ASN B 1 346 ? 33.356  2.788   0.836   1   23.089 ? 338  ASN B CB  1 
ATOM   6738 C  CG  . ASN B 1 346 ? 33.148  1.618   1.778   1   21.945 ? 338  ASN B CG  1 
ATOM   6739 O  OD1 . ASN B 1 346 ? 32.15   0.874   1.644   1   22.239 ? 338  ASN B OD1 1 
ATOM   6740 N  ND2 . ASN B 1 346 ? 34.056  1.437   2.729   1   19.127 ? 338  ASN B ND2 1 
ATOM   6741 N  N   . ALA B 1 347 ? 29.769  2.534   0.328   1   21.468 ? 339  ALA B N   1 
ATOM   6742 C  CA  . ALA B 1 347 ? 28.471  2.619   1.001   1   23.974 ? 339  ALA B CA  1 
ATOM   6743 C  C   . ALA B 1 347 ? 28.479  1.942   2.374   1   23.245 ? 339  ALA B C   1 
ATOM   6744 O  O   . ALA B 1 347 ? 27.498  2.094   3.137   1   25.06  ? 339  ALA B O   1 
ATOM   6745 C  CB  . ALA B 1 347 ? 27.373  2       0.132   1   23.562 ? 339  ALA B CB  1 
ATOM   6746 N  N   . PHE B 1 348 ? 29.539  1.156   2.661   1   19.71  ? 340  PHE B N   1 
ATOM   6747 C  CA  . PHE B 1 348 ? 29.715  0.544   3.977   1   20.591 ? 340  PHE B CA  1 
ATOM   6748 C  C   . PHE B 1 348 ? 30.998  1.088   4.611   1   20.593 ? 340  PHE B C   1 
ATOM   6749 O  O   . PHE B 1 348 ? 31.979  0.352   4.789   1   19.867 ? 340  PHE B O   1 
ATOM   6750 C  CB  . PHE B 1 348 ? 29.865  -0.991  3.904   1   21.697 ? 340  PHE B CB  1 
ATOM   6751 C  CG  . PHE B 1 348 ? 28.623  -1.834  3.635   1   21.319 ? 340  PHE B CG  1 
ATOM   6752 C  CD1 . PHE B 1 348 ? 27.344  -1.262  3.636   1   23.189 ? 340  PHE B CD1 1 
ATOM   6753 C  CD2 . PHE B 1 348 ? 28.751  -3.214  3.501   1   20.227 ? 340  PHE B CD2 1 
ATOM   6754 C  CE1 . PHE B 1 348 ? 26.204  -2.072  3.471   1   26.883 ? 340  PHE B CE1 1 
ATOM   6755 C  CE2 . PHE B 1 348 ? 27.609  -4.026  3.373   1   23.099 ? 340  PHE B CE2 1 
ATOM   6756 C  CZ  . PHE B 1 348 ? 26.344  -3.446  3.333   1   22.537 ? 340  PHE B CZ  1 
ATOM   6757 N  N   . PRO B 1 349 ? 31.027  2.38    5.018   1   22.48  ? 341  PRO B N   1 
ATOM   6758 C  CA  . PRO B 1 349 ? 32.263  2.98    5.509   1   24.071 ? 341  PRO B CA  1 
ATOM   6759 C  C   . PRO B 1 349 ? 32.772  2.355   6.808   1   23.23  ? 341  PRO B C   1 
ATOM   6760 O  O   . PRO B 1 349 ? 33.937  2.535   7.138   1   23.403 ? 341  PRO B O   1 
ATOM   6761 C  CB  . PRO B 1 349 ? 31.882  4.45    5.74    1   25.92  ? 341  PRO B CB  1 
ATOM   6762 C  CG  . PRO B 1 349 ? 30.369  4.411   5.972   1   22.975 ? 341  PRO B CG  1 
ATOM   6763 C  CD  . PRO B 1 349 ? 29.909  3.335   5.005   1   21.908 ? 341  PRO B CD  1 
ATOM   6764 N  N   . PHE B 1 350 ? 31.926  1.556   7.489   1   23.778 ? 342  PHE B N   1 
ATOM   6765 C  CA  . PHE B 1 350 ? 32.291  0.831   8.706   1   24.029 ? 342  PHE B CA  1 
ATOM   6766 C  C   . PHE B 1 350 ? 33.218  -0.355  8.384   1   20.562 ? 342  PHE B C   1 
ATOM   6767 O  O   . PHE B 1 350 ? 33.764  -0.983  9.296   1   23.659 ? 342  PHE B O   1 
ATOM   6768 C  CB  . PHE B 1 350 ? 31.046  0.394   9.516   1   22.59  ? 342  PHE B CB  1 
ATOM   6769 C  CG  . PHE B 1 350 ? 29.954  -0.247  8.663   1   21.287 ? 342  PHE B CG  1 
ATOM   6770 C  CD1 . PHE B 1 350 ? 29.98   -1.621  8.359   1   24.517 ? 342  PHE B CD1 1 
ATOM   6771 C  CD2 . PHE B 1 350 ? 28.934  0.535   8.087   1   24.645 ? 342  PHE B CD2 1 
ATOM   6772 C  CE1 . PHE B 1 350 ? 29.006  -2.206  7.545   1   22.245 ? 342  PHE B CE1 1 
ATOM   6773 C  CE2 . PHE B 1 350 ? 27.956  -0.042  7.292   1   23.673 ? 342  PHE B CE2 1 
ATOM   6774 C  CZ  . PHE B 1 350 ? 27.998  -1.4    7.017   1   23.969 ? 342  PHE B CZ  1 
ATOM   6775 N  N   . PHE B 1 351 ? 33.384  -0.685  7.096   1   21.017 ? 343  PHE B N   1 
ATOM   6776 C  CA  . PHE B 1 351 ? 34.417  -1.616  6.619   1   19.786 ? 343  PHE B CA  1 
ATOM   6777 C  C   . PHE B 1 351 ? 35.419  -0.818  5.797   1   20.645 ? 343  PHE B C   1 
ATOM   6778 O  O   . PHE B 1 351 ? 35.502  -0.981  4.571   1   25.596 ? 343  PHE B O   1 
ATOM   6779 C  CB  . PHE B 1 351 ? 33.873  -2.823  5.83    1   18.982 ? 343  PHE B CB  1 
ATOM   6780 C  CG  . PHE B 1 351 ? 32.836  -3.685  6.55    1   20.194 ? 343  PHE B CG  1 
ATOM   6781 C  CD1 . PHE B 1 351 ? 32.868  -3.849  7.945   1   20.943 ? 343  PHE B CD1 1 
ATOM   6782 C  CD2 . PHE B 1 351 ? 31.844  -4.358  5.795   1   21.007 ? 343  PHE B CD2 1 
ATOM   6783 C  CE1 . PHE B 1 351 ? 31.95   -4.684  8.611   1   21.447 ? 343  PHE B CE1 1 
ATOM   6784 C  CE2 . PHE B 1 351 ? 30.911  -5.175  6.452   1   22.077 ? 343  PHE B CE2 1 
ATOM   6785 C  CZ  . PHE B 1 351 ? 30.944  -5.304  7.852   1   20.882 ? 343  PHE B CZ  1 
ATOM   6786 N  N   . PRO B 1 352 ? 36.252  0.03    6.435   1   22.895 ? 344  PRO B N   1 
ATOM   6787 C  CA  . PRO B 1 352 ? 37.144  0.897   5.671   1   22.622 ? 344  PRO B CA  1 
ATOM   6788 C  C   . PRO B 1 352 ? 38.266  0.139   4.961   1   22.695 ? 344  PRO B C   1 
ATOM   6789 O  O   . PRO B 1 352 ? 38.516  -1.041  5.228   1   23.62  ? 344  PRO B O   1 
ATOM   6790 C  CB  . PRO B 1 352 ? 37.666  1.855   6.755   1   24.127 ? 344  PRO B CB  1 
ATOM   6791 C  CG  . PRO B 1 352 ? 37.731  0.971   7.97    1   24.88  ? 344  PRO B CG  1 
ATOM   6792 C  CD  . PRO B 1 352 ? 36.439  0.172   7.896   1   21.844 ? 344  PRO B CD  1 
ATOM   6793 N  N   . PRO B 1 353 ? 39.069  0.814   4.098   1   22.595 ? 345  PRO B N   1 
ATOM   6794 C  CA  . PRO B 1 353 ? 40.259  0.197   3.542   1   23.462 ? 345  PRO B CA  1 
ATOM   6795 C  C   . PRO B 1 353 ? 41.284  -0.132  4.609   1   22.656 ? 345  PRO B C   1 
ATOM   6796 O  O   . PRO B 1 353 ? 41.228  0.402   5.726   1   24.158 ? 345  PRO B O   1 
ATOM   6797 C  CB  . PRO B 1 353 ? 40.818  1.301   2.639   1   23.337 ? 345  PRO B CB  1 
ATOM   6798 C  CG  . PRO B 1 353 ? 39.586  2.13    2.292   1   24.132 ? 345  PRO B CG  1 
ATOM   6799 C  CD  . PRO B 1 353 ? 38.857  2.175   3.588   1   23.003 ? 345  PRO B CD  1 
ATOM   6800 N  N   . ASP B 1 354 ? 42.209  -1.003  4.226   1   26.065 ? 346  ASP B N   1 
ATOM   6801 C  CA  . ASP B 1 354 ? 43.315  -1.413  5.071   1   32.013 ? 346  ASP B CA  1 
ATOM   6802 C  C   . ASP B 1 354 ? 44.349  -0.297  5.242   1   30.563 ? 346  ASP B C   1 
ATOM   6803 O  O   . ASP B 1 354 ? 44.761  0.007   6.364   1   31.665 ? 346  ASP B O   1 
ATOM   6804 C  CB  . ASP B 1 354 ? 43.988  -2.603  4.4     1   36.42  ? 346  ASP B CB  1 
ATOM   6805 C  CG  . ASP B 1 354 ? 44.542  -3.648  5.336   1   50.827 ? 346  ASP B CG  1 
ATOM   6806 O  OD1 . ASP B 1 354 ? 43.723  -4.322  5.971   1   45.584 ? 346  ASP B OD1 1 
ATOM   6807 O  OD2 . ASP B 1 354 ? 45.788  -3.742  5.424   1   63.724 ? 346  ASP B OD2 1 
ATOM   6808 N  N   . SER B 1 355 ? 44.776  0.311   4.127   1   30.616 ? 347  SER B N   1 
ATOM   6809 C  CA  . SER B 1 355 ? 45.954  1.18    4.178   1   28.173 ? 347  SER B CA  1 
ATOM   6810 C  C   . SER B 1 355 ? 45.574  2.563   4.693   1   29.84  ? 347  SER B C   1 
ATOM   6811 O  O   . SER B 1 355 ? 44.452  3.034   4.472   1   25.854 ? 347  SER B O   1 
ATOM   6812 C  CB  . SER B 1 355 ? 46.648  1.276   2.84    1   28.687 ? 347  SER B CB  1 
ATOM   6813 O  OG  . SER B 1 355 ? 45.851  2.013   1.917   1   30.504 ? 347  SER B OG  1 
ATOM   6814 N  N   . ASP B 1 356 ? 46.546  3.241   5.322   1   29.566 ? 348  ASP B N   1 
ATOM   6815 C  CA  . ASP B 1 356 ? 46.324  4.606   5.778   1   33.134 ? 348  ASP B CA  1 
ATOM   6816 C  C   . ASP B 1 356 ? 45.948  5.503   4.609   1   29.976 ? 348  ASP B C   1 
ATOM   6817 O  O   . ASP B 1 356 ? 45.002  6.293   4.746   1   28.408 ? 348  ASP B O   1 
ATOM   6818 C  CB  . ASP B 1 356 ? 47.502  5.124   6.58    1   37.001 ? 348  ASP B CB  1 
ATOM   6819 C  CG  . ASP B 1 356 ? 47.644  4.535   7.972   1   46.556 ? 348  ASP B CG  1 
ATOM   6820 O  OD1 . ASP B 1 356 ? 46.66   3.948   8.496   1   56.034 ? 348  ASP B OD1 1 
ATOM   6821 O  OD2 . ASP B 1 356 ? 48.757  4.635   8.508   1   56.828 ? 348  ASP B OD2 1 
ATOM   6822 N  N   . GLU B 1 357 ? 46.652  5.338   3.472   1   27.734 ? 349  GLU B N   1 
ATOM   6823 C  CA  . GLU B 1 357 ? 46.361  6.11    2.269   1   27.058 ? 349  GLU B CA  1 
ATOM   6824 C  C   . GLU B 1 357 ? 44.886  5.996   1.854   1   28.344 ? 349  GLU B C   1 
ATOM   6825 O  O   . GLU B 1 357 ? 44.207  6.996   1.566   1   22.923 ? 349  GLU B O   1 
ATOM   6826 C  CB  . GLU B 1 357 ? 47.337  5.772   1.139   1   32.576 ? 349  GLU B CB  1 
ATOM   6827 C  CG  . GLU B 1 357 ? 46.915  6.422   -0.17   1   44.332 ? 349  GLU B CG  1 
ATOM   6828 C  CD  . GLU B 1 357 ? 47.539  6.094   -1.501  1   55.191 ? 349  GLU B CD  1 
ATOM   6829 O  OE1 . GLU B 1 357 ? 48.483  5.274   -1.607  1   56.551 ? 349  GLU B OE1 1 
ATOM   6830 O  OE2 . GLU B 1 357 ? 47.032  6.749   -2.437  1   51.289 ? 349  GLU B OE2 1 
ATOM   6831 N  N   . GLN B 1 358 ? 44.392  4.753   1.745   1   22.36  ? 350  GLN B N   1 
ATOM   6832 C  CA  . GLN B 1 358 ? 43.031  4.58    1.26    1   22.605 ? 350  GLN B CA  1 
ATOM   6833 C  C   . GLN B 1 358 ? 42.009  4.998   2.32    1   21.61  ? 350  GLN B C   1 
ATOM   6834 O  O   . GLN B 1 358 ? 40.919  5.457   1.951   1   24.772 ? 350  GLN B O   1 
ATOM   6835 C  CB  . GLN B 1 358 ? 42.796  3.135   0.822   1   24.752 ? 350  GLN B CB  1 
ATOM   6836 C  CG  . GLN B 1 358 ? 43.487  2.768   -0.488  1   22.409 ? 350  GLN B CG  1 
ATOM   6837 C  CD  . GLN B 1 358 ? 42.827  1.581   -1.154  1   25.851 ? 350  GLN B CD  1 
ATOM   6838 O  OE1 . GLN B 1 358 ? 41.637  1.325   -0.938  1   22.665 ? 350  GLN B OE1 1 
ATOM   6839 N  NE2 . GLN B 1 358 ? 43.575  0.891   -2.012  1   23.732 ? 350  GLN B NE2 1 
ATOM   6840 N  N   . LYS B 1 359 ? 42.33   4.832   3.607   1   21.195 ? 351  LYS B N   1 
ATOM   6841 C  CA  . LYS B 1 359 ? 41.501  5.348   4.693   1   23.076 ? 351  LYS B CA  1 
ATOM   6842 C  C   . LYS B 1 359 ? 41.29   6.848   4.526   1   21.843 ? 351  LYS B C   1 
ATOM   6843 O  O   . LYS B 1 359 ? 40.186  7.323   4.64    1   23.502 ? 351  LYS B O   1 
ATOM   6844 C  CB  . LYS B 1 359 ? 42.033  5.131   6.112   1   24.174 ? 351  LYS B CB  1 
ATOM   6845 C  CG  . LYS B 1 359 ? 41.87   3.667   6.532   1   32.434 ? 351  LYS B CG  1 
ATOM   6846 C  CD  . LYS B 1 359 ? 42.464  3.594   7.939   1   36.568 ? 351  LYS B CD  1 
ATOM   6847 C  CE  . LYS B 1 359 ? 42.797  2.214   8.399   1   49.629 ? 351  LYS B CE  1 
ATOM   6848 N  NZ  . LYS B 1 359 ? 41.545  1.496   8.614   1   52.453 ? 351  LYS B NZ  1 
ATOM   6849 N  N   . LYS B 1 360 ? 42.374  7.586   4.244   1   22.561 ? 352  LYS B N   1 
ATOM   6850 C  CA  . LYS B 1 360 ? 42.272  9.032   4.066   1   22.508 ? 352  LYS B CA  1 
ATOM   6851 C  C   . LYS B 1 360 ? 41.38   9.374   2.869   1   22.383 ? 352  LYS B C   1 
ATOM   6852 O  O   . LYS B 1 360 ? 40.616  10.342  2.939   1   23.538 ? 352  LYS B O   1 
ATOM   6853 C  CB  . LYS B 1 360 ? 43.683  9.612   3.895   1   19.485 ? 352  LYS B CB  1 
ATOM   6854 C  CG  . LYS B 1 360 ? 44.475  9.569   5.197   1   23.802 ? 352  LYS B CG  1 
ATOM   6855 C  CD  . LYS B 1 360 ? 45.79   10.349  5.082   1   23.552 ? 352  LYS B CD  1 
ATOM   6856 C  CE  . LYS B 1 360 ? 46.684  10.048  6.247   1   24.21  ? 352  LYS B CE  1 
ATOM   6857 N  NZ  . LYS B 1 360 ? 46.129  10.297  7.577   1   25.833 ? 352  LYS B NZ  1 
ATOM   6858 N  N   . LYS B 1 361 ? 41.479  8.589   1.784   1   23.69  ? 353  LYS B N   1 
ATOM   6859 C  CA  . LYS B 1 361 ? 40.618  8.787   0.615   1   24.428 ? 353  LYS B CA  1 
ATOM   6860 C  C   . LYS B 1 361 ? 39.136  8.618   0.995   1   23.268 ? 353  LYS B C   1 
ATOM   6861 O  O   . LYS B 1 361 ? 38.278  9.396   0.57    1   21.278 ? 353  LYS B O   1 
ATOM   6862 C  CB  . LYS B 1 361 ? 40.98   7.836   -0.534  1   23.508 ? 353  LYS B CB  1 
ATOM   6863 C  CG  . LYS B 1 361 ? 40.121  8.111   -1.77   1   27.525 ? 353  LYS B CG  1 
ATOM   6864 C  CD  . LYS B 1 361 ? 40.749  7.555   -3.039  1   33.176 ? 353  LYS B CD  1 
ATOM   6865 C  CE  . LYS B 1 361 ? 39.855  7.652   -4.257  1   36.078 ? 353  LYS B CE  1 
ATOM   6866 N  NZ  . LYS B 1 361 ? 39.254  8.985   -4.379  1   45.444 ? 353  LYS B NZ  1 
ATOM   6867 N  N   . GLN B 1 362 ? 38.853  7.595   1.799   1   23.332 ? 354  GLN B N   1 
ATOM   6868 C  CA  . GLN B 1 362 ? 37.48   7.349   2.222   1   23.439 ? 354  GLN B CA  1 
ATOM   6869 C  C   . GLN B 1 362 ? 36.94   8.57    2.972   1   23.582 ? 354  GLN B C   1 
ATOM   6870 O  O   . GLN B 1 362 ? 35.834  9.013   2.703   1   23.388 ? 354  GLN B O   1 
ATOM   6871 C  CB  . GLN B 1 362 ? 37.301  6.049   3.016   1   25.073 ? 354  GLN B CB  1 
ATOM   6872 C  CG  . GLN B 1 362 ? 35.842  5.808   3.404   1   25.372 ? 354  GLN B CG  1 
ATOM   6873 C  CD  . GLN B 1 362 ? 35.657  4.505   4.161   1   25.306 ? 354  GLN B CD  1 
ATOM   6874 O  OE1 . GLN B 1 362 ? 35.816  3.429   3.588   1   26.247 ? 354  GLN B OE1 1 
ATOM   6875 N  NE2 . GLN B 1 362 ? 35.337  4.607   5.437   1   23.595 ? 354  GLN B NE2 1 
ATOM   6876 N  N   . GLU B 1 363 ? 37.737  9.096   3.916   1   21.927 ? 355  GLU B N   1 
ATOM   6877 C  CA  . GLU B 1 363 ? 37.342  10.252  4.693   1   23.939 ? 355  GLU B CA  1 
ATOM   6878 C  C   . GLU B 1 363 ? 37.167  11.463  3.783   1   23.664 ? 355  GLU B C   1 
ATOM   6879 O  O   . GLU B 1 363 ? 36.125  12.16   3.867   1   22.499 ? 355  GLU B O   1 
ATOM   6880 C  CB  . GLU B 1 363 ? 38.338  10.518  5.818   1   24.778 ? 355  GLU B CB  1 
ATOM   6881 C  CG  . GLU B 1 363 ? 37.765  11.58   6.746   1   30.717 ? 355  GLU B CG  1 
ATOM   6882 C  CD  . GLU B 1 363 ? 38.469  11.721  8.078   1   34.125 ? 355  GLU B CD  1 
ATOM   6883 O  OE1 . GLU B 1 363 ? 39.529  11.074  8.274   1   34.35  ? 355  GLU B OE1 1 
ATOM   6884 O  OE2 . GLU B 1 363 ? 37.957  12.534  8.886   1   32.512 ? 355  GLU B OE2 1 
ATOM   6885 N  N   . ALA B 1 364 ? 38.128  11.646  2.87    1   24.331 ? 356  ALA B N   1 
ATOM   6886 C  CA  . ALA B 1 364 ? 38.088  12.742  1.896   1   22.853 ? 356  ALA B CA  1 
ATOM   6887 C  C   . ALA B 1 364 ? 36.827  12.726  1.042   1   24.727 ? 356  ALA B C   1 
ATOM   6888 O  O   . ALA B 1 364 ? 36.22   13.772  0.816   1   27.577 ? 356  ALA B O   1 
ATOM   6889 C  CB  . ALA B 1 364 ? 39.352  12.823  1.063   1   25.18  ? 356  ALA B CB  1 
ATOM   6890 N  N   . ASP B 1 365 ? 36.458  11.552  0.545   1   22.8   ? 357  ASP B N   1 
ATOM   6891 C  CA  . ASP B 1 365 ? 35.33   11.4    -0.373  1   25.864 ? 357  ASP B CA  1 
ATOM   6892 C  C   . ASP B 1 365 ? 34.001  11.748  0.29    1   26.064 ? 357  ASP B C   1 
ATOM   6893 O  O   . ASP B 1 365 ? 33.071  12.138  -0.418  1   30.267 ? 357  ASP B O   1 
ATOM   6894 C  CB  . ASP B 1 365 ? 35.243  9.994   -0.952  1   26.043 ? 357  ASP B CB  1 
ATOM   6895 C  CG  . ASP B 1 365 ? 36.194  9.705   -2.105  1   32.227 ? 357  ASP B CG  1 
ATOM   6896 O  OD1 . ASP B 1 365 ? 36.89   10.65   -2.551  1   31.651 ? 357  ASP B OD1 1 
ATOM   6897 O  OD2 . ASP B 1 365 ? 36.269  8.525   -2.507  1   38.87  ? 357  ASP B OD2 1 
ATOM   6898 N  N   . GLY B 1 366 ? 33.894  11.569  1.609   1   23.537 ? 358  GLY B N   1 
ATOM   6899 C  CA  . GLY B 1 366 ? 32.638  11.757  2.329   1   27.736 ? 358  GLY B CA  1 
ATOM   6900 C  C   . GLY B 1 366 ? 31.52   10.889  1.756   1   28.858 ? 358  GLY B C   1 
ATOM   6901 O  O   . GLY B 1 366 ? 31.81   9.795   1.332   1   30.275 ? 358  GLY B O   1 
ATOM   6902 N  N   . THR B 1 367 ? 30.277  11.388  1.694   1   29.144 ? 359  THR B N   1 
ATOM   6903 C  CA  . THR B 1 367 ? 29.166  10.595  1.176   1   27.111 ? 359  THR B CA  1 
ATOM   6904 C  C   . THR B 1 367 ? 29.27   10.541  -0.345  1   25.914 ? 359  THR B C   1 
ATOM   6905 O  O   . THR B 1 367 ? 29.225  11.582  -0.986  1   25.691 ? 359  THR B O   1 
ATOM   6906 C  CB  . THR B 1 367 ? 27.831  11.228  1.575   1   27.867 ? 359  THR B CB  1 
ATOM   6907 O  OG1 . THR B 1 367 ? 27.763  11.153  2.987   1   26.56  ? 359  THR B OG1 1 
ATOM   6908 C  CG2 . THR B 1 367 ? 26.627  10.51   0.99    1   28.905 ? 359  THR B CG2 1 
ATOM   6909 N  N   . PRO B 1 368 ? 29.43   9.359   -0.982  1   23.886 ? 360  PRO B N   1 
ATOM   6910 C  CA  . PRO B 1 368 ? 29.61   9.305   -2.436  1   23.733 ? 360  PRO B CA  1 
ATOM   6911 C  C   . PRO B 1 368 ? 28.346  9.64    -3.21   1   24.962 ? 360  PRO B C   1 
ATOM   6912 O  O   . PRO B 1 368 ? 27.233  9.547   -2.671  1   26.149 ? 360  PRO B O   1 
ATOM   6913 C  CB  . PRO B 1 368 ? 30.09   7.858   -2.698  1   25.048 ? 360  PRO B CB  1 
ATOM   6914 C  CG  . PRO B 1 368 ? 30.431  7.326   -1.321  1   25.13  ? 360  PRO B CG  1 
ATOM   6915 C  CD  . PRO B 1 368 ? 29.586  8.033   -0.35   1   24.641 ? 360  PRO B CD  1 
ATOM   6916 N  N   . LYS B 1 369 ? 28.54   9.97    -4.496  1   26.57  ? 361  LYS B N   1 
ATOM   6917 C  CA  . LYS B 1 369 ? 27.449  10.078  -5.436  1   25.039 ? 361  LYS B CA  1 
ATOM   6918 C  C   . LYS B 1 369 ? 26.769  8.712   -5.549  1   26.359 ? 361  LYS B C   1 
ATOM   6919 O  O   . LYS B 1 369 ? 27.458  7.693   -5.535  1   23.704 ? 361  LYS B O   1 
ATOM   6920 C  CB  . LYS B 1 369 ? 28.07   10.408  -6.791  1   25.809 ? 361  LYS B CB  1 
ATOM   6921 C  CG  . LYS B 1 369 ? 27.01   10.761  -7.849  1   36.522 ? 361  LYS B CG  1 
ATOM   6922 C  CD  . LYS B 1 369 ? 27.575  11.281  -9.173  1   37.812 ? 361  LYS B CD  1 
ATOM   6923 C  CE  . LYS B 1 369 ? 28.441  10.341  -9.979  1   40.409 ? 361  LYS B CE  1 
ATOM   6924 N  NZ  . LYS B 1 369 ? 28.917  10.869  -11.26  1   43.729 ? 361  LYS B NZ  1 
ATOM   6925 N  N   . ALA B 1 370 ? 25.431  8.714   -5.657  1   24.119 ? 362  ALA B N   1 
ATOM   6926 C  CA  . ALA B 1 370 ? 24.662  7.482   -5.724  1   24.922 ? 362  ALA B CA  1 
ATOM   6927 C  C   . ALA B 1 370 ? 23.568  7.627   -6.772  1   22.982 ? 362  ALA B C   1 
ATOM   6928 O  O   . ALA B 1 370 ? 22.896  8.66    -6.823  1   23.9   ? 362  ALA B O   1 
ATOM   6929 C  CB  . ALA B 1 370 ? 24.084  7.165   -4.354  1   23.159 ? 362  ALA B CB  1 
ATOM   6930 N  N   . GLN B 1 371 ? 23.443  6.615   -7.623  1   23.157 ? 363  GLN B N   1 
ATOM   6931 C  CA  . GLN B 1 371 ? 22.528  6.628   -8.756  1   22.418 ? 363  GLN B CA  1 
ATOM   6932 C  C   . GLN B 1 371 ? 21.985  5.229   -9.004  1   22.66  ? 363  GLN B C   1 
ATOM   6933 O  O   . GLN B 1 371 ? 22.33   4.287   -8.286  1   22.075 ? 363  GLN B O   1 
ATOM   6934 C  CB  . GLN B 1 371 ? 23.277  7.037   -10.039 1   26.865 ? 363  GLN B CB  1 
ATOM   6935 C  CG  . GLN B 1 371 ? 23.948  8.41    -9.948  1   27.509 ? 363  GLN B CG  1 
ATOM   6936 C  CD  . GLN B 1 371 ? 24.904  8.663   -11.097 1   32.573 ? 363  GLN B CD  1 
ATOM   6937 O  OE1 . GLN B 1 371 ? 25.738  7.806   -11.413 1   32.107 ? 363  GLN B OE1 1 
ATOM   6938 N  NE2 . GLN B 1 371 ? 24.799  9.846   -11.711 1   30.18  ? 363  GLN B NE2 1 
ATOM   6939 N  N   . PHE B 1 372 ? 21.027  5.135   -9.945  1   22.046 ? 364  PHE B N   1 
ATOM   6940 C  CA  . PHE B 1 372 ? 20.521  3.873   -10.441 1   24.182 ? 364  PHE B CA  1 
ATOM   6941 C  C   . PHE B 1 372 ? 20.944  3.806   -11.909 1   28.364 ? 364  PHE B C   1 
ATOM   6942 O  O   . PHE B 1 372 ? 20.687  4.772   -12.642 1   24.269 ? 364  PHE B O   1 
ATOM   6943 C  CB  . PHE B 1 372 ? 18.989  3.877   -10.308 1   24.87  ? 364  PHE B CB  1 
ATOM   6944 C  CG  . PHE B 1 372 ? 18.376  2.528   -10.655 1   30.322 ? 364  PHE B CG  1 
ATOM   6945 C  CD1 . PHE B 1 372 ? 18.554  1.429   -9.8    1   29.704 ? 364  PHE B CD1 1 
ATOM   6946 C  CD2 . PHE B 1 372 ? 17.586  2.374   -11.813 1   29.61  ? 364  PHE B CD2 1 
ATOM   6947 C  CE1 . PHE B 1 372 ? 17.995  0.183   -10.13  1   28.991 ? 364  PHE B CE1 1 
ATOM   6948 C  CE2 . PHE B 1 372 ? 17.025  1.137   -12.137 1   29.553 ? 364  PHE B CE2 1 
ATOM   6949 C  CZ  . PHE B 1 372 ? 17.226  0.048   -11.273 1   30.26  ? 364  PHE B CZ  1 
ATOM   6950 N  N   . VAL B 1 373 ? 21.635  2.716   -12.297 1   25.523 ? 365  VAL B N   1 
ATOM   6951 C  CA  . VAL B 1 373 ? 22.339  2.685   -13.584 1   23.706 ? 365  VAL B CA  1 
ATOM   6952 C  C   . VAL B 1 373 ? 22.027  1.394   -14.331 1   24.613 ? 365  VAL B C   1 
ATOM   6953 O  O   . VAL B 1 373 ? 21.572  0.423   -13.739 1   23.201 ? 365  VAL B O   1 
ATOM   6954 C  CB  . VAL B 1 373 ? 23.869  2.867   -13.408 1   27.424 ? 365  VAL B CB  1 
ATOM   6955 C  CG1 . VAL B 1 373 ? 24.229  4.11    -12.615 1   29.104 ? 365  VAL B CG1 1 
ATOM   6956 C  CG2 . VAL B 1 373 ? 24.534  1.632   -12.781 1   23.488 ? 365  VAL B CG2 1 
ATOM   6957 N  N   . ARG B 1 374 ? 22.374  1.356   -15.636 1   21.865 ? 366  ARG B N   1 
ATOM   6958 C  CA  . ARG B 1 374 ? 22.197  0.196   -16.492 1   22.274 ? 366  ARG B CA  1 
ATOM   6959 C  C   . ARG B 1 374 ? 23.553  -0.207  -17.091 1   23.903 ? 366  ARG B C   1 
ATOM   6960 O  O   . ARG B 1 374 ? 24.209  0.595   -17.768 1   23.595 ? 366  ARG B O   1 
ATOM   6961 C  CB  . ARG B 1 374 ? 21.206  0.504   -17.631 1   24.229 ? 366  ARG B CB  1 
ATOM   6962 C  CG  . ARG B 1 374 ? 21.049  -0.666  -18.602 1   23.431 ? 366  ARG B CG  1 
ATOM   6963 C  CD  . ARG B 1 374 ? 19.813  -0.418  -19.518 1   26.645 ? 366  ARG B CD  1 
ATOM   6964 N  NE  . ARG B 1 374 ? 18.566  -0.428  -18.732 1   25.135 ? 366  ARG B NE  1 
ATOM   6965 C  CZ  . ARG B 1 374 ? 17.614  0.516   -18.818 1   27.559 ? 366  ARG B CZ  1 
ATOM   6966 N  NH1 . ARG B 1 374 ? 17.41   1.227   -19.933 1   25.032 ? 366  ARG B NH1 1 
ATOM   6967 N  NH2 . ARG B 1 374 ? 16.777  0.662   -17.797 1   27.292 ? 366  ARG B NH2 1 
ATOM   6968 N  N   . TRP B 1 375 ? 23.92   -1.483  -16.895 1   24.978 ? 367  TRP B N   1 
ATOM   6969 C  CA  . TRP B 1 375 ? 25.152  -2.101  -17.389 1   25.804 ? 367  TRP B CA  1 
ATOM   6970 C  C   . TRP B 1 375 ? 24.824  -2.885  -18.652 1   23.861 ? 367  TRP B C   1 
ATOM   6971 O  O   . TRP B 1 375 ? 23.738  -3.452  -18.743 1   24.75  ? 367  TRP B O   1 
ATOM   6972 C  CB  . TRP B 1 375 ? 25.654  -3.092  -16.338 1   22.752 ? 367  TRP B CB  1 
ATOM   6973 C  CG  . TRP B 1 375 ? 25.892  -2.46   -14.994 1   22.656 ? 367  TRP B CG  1 
ATOM   6974 C  CD1 . TRP B 1 375 ? 25.001  -2.418  -13.946 1   22.815 ? 367  TRP B CD1 1 
ATOM   6975 C  CD2 . TRP B 1 375 ? 27.097  -1.799  -14.53  1   25.134 ? 367  TRP B CD2 1 
ATOM   6976 N  NE1 . TRP B 1 375 ? 25.557  -1.756  -12.886 1   21.496 ? 367  TRP B NE1 1 
ATOM   6977 C  CE2 . TRP B 1 375 ? 26.838  -1.37   -13.201 1   26.014 ? 367  TRP B CE2 1 
ATOM   6978 C  CE3 . TRP B 1 375 ? 28.368  -1.537  -15.09  1   28.53  ? 367  TRP B CE3 1 
ATOM   6979 C  CZ2 . TRP B 1 375 ? 27.803  -0.712  -12.428 1   26.835 ? 367  TRP B CZ2 1 
ATOM   6980 C  CZ3 . TRP B 1 375 ? 29.314  -0.889  -14.317 1   28.337 ? 367  TRP B CZ3 1 
ATOM   6981 C  CH2 . TRP B 1 375 ? 29.038  -0.492  -12.998 1   30.67  ? 367  TRP B CH2 1 
ATOM   6982 N  N   . THR B 1 376 ? 25.781  -2.918  -19.585 1   22.42  ? 368  THR B N   1 
ATOM   6983 C  CA  . THR B 1 376 ? 25.709  -3.744  -20.783 1   24.733 ? 368  THR B CA  1 
ATOM   6984 C  C   . THR B 1 376 ? 26.97   -4.607  -20.81  1   23.625 ? 368  THR B C   1 
ATOM   6985 O  O   . THR B 1 376 ? 28.092  -4.095  -20.844 1   27.156 ? 368  THR B O   1 
ATOM   6986 C  CB  . THR B 1 376 ? 25.581  -2.882  -22.047 1   26.491 ? 368  THR B CB  1 
ATOM   6987 O  OG1 . THR B 1 376 ? 24.384  -2.116  -21.939 1   26.814 ? 368  THR B OG1 1 
ATOM   6988 C  CG2 . THR B 1 376 ? 25.416  -3.746  -23.286 1   26.174 ? 368  THR B CG2 1 
ATOM   6989 N  N   . ILE B 1 377 ? 26.762  -5.925  -20.765 1   24.672 ? 369  ILE B N   1 
ATOM   6990 C  CA  . ILE B 1 377 ? 27.833  -6.905  -20.85  1   25.392 ? 369  ILE B CA  1 
ATOM   6991 C  C   . ILE B 1 377 ? 27.508  -7.696  -22.104 1   25.516 ? 369  ILE B C   1 
ATOM   6992 O  O   . ILE B 1 377 ? 26.572  -8.508  -22.131 1   26.708 ? 369  ILE B O   1 
ATOM   6993 C  CB  . ILE B 1 377 ? 27.924  -7.823  -19.612 1   25.166 ? 369  ILE B CB  1 
ATOM   6994 C  CG1 . ILE B 1 377 ? 28.152  -7.039  -18.332 1   26.358 ? 369  ILE B CG1 1 
ATOM   6995 C  CG2 . ILE B 1 377 ? 29.011  -8.891  -19.832 1   25.454 ? 369  ILE B CG2 1 
ATOM   6996 C  CD1 . ILE B 1 377 ? 27.963  -7.866  -17.044 1   26.214 ? 369  ILE B CD1 1 
ATOM   6997 N  N   . ASP B 1 378 ? 28.251  -7.362  -23.157 1   27.502 ? 370  ASP B N   1 
ATOM   6998 C  CA  . ASP B 1 378 ? 28.005  -7.937  -24.471 1   29.343 ? 370  ASP B CA  1 
ATOM   6999 C  C   . ASP B 1 378 ? 28.916  -9.154  -24.618 1   28.595 ? 370  ASP B C   1 
ATOM   7000 O  O   . ASP B 1 378 ? 30.13   -8.998  -24.734 1   29.175 ? 370  ASP B O   1 
ATOM   7001 C  CB  . ASP B 1 378 ? 28.193  -6.892  -25.561 1   27.788 ? 370  ASP B CB  1 
ATOM   7002 C  CG  . ASP B 1 378 ? 27.924  -7.374  -26.99  1   31.992 ? 370  ASP B CG  1 
ATOM   7003 O  OD1 . ASP B 1 378 ? 27.785  -8.599  -27.194 1   27.348 ? 370  ASP B OD1 1 
ATOM   7004 O  OD2 . ASP B 1 378 ? 27.788  -6.492  -27.873 1   34.029 ? 370  ASP B OD2 1 
ATOM   7005 N  N   . PRO B 1 379 ? 28.377  -10.401 -24.578 1   28.546 ? 371  PRO B N   1 
ATOM   7006 C  CA  . PRO B 1 379 ? 29.219  -11.592 -24.629 1   29.283 ? 371  PRO B CA  1 
ATOM   7007 C  C   . PRO B 1 379 ? 29.946  -11.813 -25.961 1   30.791 ? 371  PRO B C   1 
ATOM   7008 O  O   . PRO B 1 379 ? 30.83   -12.656 -26.017 1   30.142 ? 371  PRO B O   1 
ATOM   7009 C  CB  . PRO B 1 379 ? 28.327  -12.751 -24.225 1   28.762 ? 371  PRO B CB  1 
ATOM   7010 C  CG  . PRO B 1 379 ? 26.936  -12.202 -24.268 1   31.414 ? 371  PRO B CG  1 
ATOM   7011 C  CD  . PRO B 1 379 ? 26.941  -10.715 -24.491 1   28.279 ? 371  PRO B CD  1 
ATOM   7012 N  N   . ARG B 1 380 ? 29.575  -11.039 -27.008 1   32.443 ? 372  ARG B N   1 
ATOM   7013 C  CA  . ARG B 1 380 ? 30.296  -11.046 -28.285 1   33.55  ? 372  ARG B CA  1 
ATOM   7014 C  C   . ARG B 1 380 ? 31.668  -10.36  -28.133 1   36.449 ? 372  ARG B C   1 
ATOM   7015 O  O   . ARG B 1 380 ? 32.559  -10.594 -28.944 1   41.291 ? 372  ARG B O   1 
ATOM   7016 C  CB  . ARG B 1 380 ? 29.442  -10.45  -29.413 1   32.323 ? 372  ARG B CB  1 
ATOM   7017 C  CG  . ARG B 1 380 ? 28.14   -11.214 -29.637 1   31.649 ? 372  ARG B CG  1 
ATOM   7018 C  CD  . ARG B 1 380 ? 27.111  -10.469 -30.494 1   34.432 ? 372  ARG B CD  1 
ATOM   7019 N  NE  . ARG B 1 380 ? 26.801  -9.104  -30.033 1   31.364 ? 372  ARG B NE  1 
ATOM   7020 C  CZ  . ARG B 1 380 ? 25.945  -8.244  -30.562 1   35.455 ? 372  ARG B CZ  1 
ATOM   7021 N  NH1 . ARG B 1 380 ? 25.216  -8.554  -31.648 1   32.63  ? 372  ARG B NH1 1 
ATOM   7022 N  NH2 . ARG B 1 380 ? 25.85   -7.038  -30.041 1   30.982 ? 372  ARG B NH2 1 
ATOM   7023 N  N   . LYS B 1 381 ? 31.862  -9.554  -27.075 1   30.068 ? 373  LYS B N   1 
ATOM   7024 C  CA  . LYS B 1 381 ? 33.051  -8.723  -26.929 1   30.392 ? 373  LYS B CA  1 
ATOM   7025 C  C   . LYS B 1 381 ? 34.131  -9.463  -26.145 1   31.764 ? 373  LYS B C   1 
ATOM   7026 O  O   . LYS B 1 381 ? 33.865  -10.461 -25.488 1   31.953 ? 373  LYS B O   1 
ATOM   7027 C  CB  . LYS B 1 381 ? 32.767  -7.36   -26.29  1   36.169 ? 373  LYS B CB  1 
ATOM   7028 C  CG  . LYS B 1 381 ? 31.845  -6.441  -27.071 1   38.922 ? 373  LYS B CG  1 
ATOM   7029 C  CD  . LYS B 1 381 ? 32.067  -5.047  -26.505 1   41.166 ? 373  LYS B CD  1 
ATOM   7030 C  CE  . LYS B 1 381 ? 31.071  -4.055  -26.977 1   52.341 ? 373  LYS B CE  1 
ATOM   7031 N  NZ  . LYS B 1 381 ? 31.102  -3.879  -28.422 1   55.764 ? 373  LYS B NZ  1 
ATOM   7032 N  N   . ASP B 1 382 ? 35.373  -8.978  -26.243 1   33.274 ? 374  ASP B N   1 
ATOM   7033 C  CA  . ASP B 1 382 ? 36.48   -9.518  -25.47  1   32.483 ? 374  ASP B CA  1 
ATOM   7034 C  C   . ASP B 1 382 ? 36.31   -9.039  -24.021 1   32.25  ? 374  ASP B C   1 
ATOM   7035 O  O   . ASP B 1 382 ? 36.318  -7.837  -23.763 1   28.413 ? 374  ASP B O   1 
ATOM   7036 C  CB  . ASP B 1 382 ? 37.794  -9.036  -26.074 1   36.733 ? 374  ASP B CB  1 
ATOM   7037 C  CG  . ASP B 1 382 ? 39.076  -9.404  -25.342 1   37.654 ? 374  ASP B CG  1 
ATOM   7038 O  OD1 . ASP B 1 382 ? 39.024  -10.119 -24.324 1   35.489 ? 374  ASP B OD1 1 
ATOM   7039 O  OD2 . ASP B 1 382 ? 40.147  -8.985  -25.81  1   46.982 ? 374  ASP B OD2 1 
ATOM   7040 N  N   . ASN B 1 383 ? 36.224  -9.991  -23.087 1   29.331 ? 375  ASN B N   1 
ATOM   7041 C  CA  . ASN B 1 383 ? 36.005  -9.695  -21.662 1   27.943 ? 375  ASN B CA  1 
ATOM   7042 C  C   . ASN B 1 383 ? 37.21   -9.01   -21.012 1   32.548 ? 375  ASN B C   1 
ATOM   7043 O  O   . ASN B 1 383 ? 37.092  -8.48   -19.905 1   30.405 ? 375  ASN B O   1 
ATOM   7044 C  CB  . ASN B 1 383 ? 35.538  -10.93  -20.888 1   26.327 ? 375  ASN B CB  1 
ATOM   7045 C  CG  . ASN B 1 383 ? 36.59   -12.016 -20.862 1   30.307 ? 375  ASN B CG  1 
ATOM   7046 O  OD1 . ASN B 1 383 ? 36.934  -12.581 -21.907 1   34.672 ? 375  ASN B OD1 1 
ATOM   7047 N  ND2 . ASN B 1 383 ? 37.139  -12.309 -19.696 1   28.418 ? 375  ASN B ND2 1 
ATOM   7048 N  N   . ASN B 1 384 ? 38.377  -9.024  -21.692 1   30.82  ? 376  ASN B N   1 
ATOM   7049 C  CA  . ASN B 1 384 ? 39.55   -8.302  -21.202 1   30.632 ? 376  ASN B CA  1 
ATOM   7050 C  C   . ASN B 1 384 ? 39.415  -6.795  -21.388 1   30.817 ? 376  ASN B C   1 
ATOM   7051 O  O   . ASN B 1 384 ? 40.104  -6.046  -20.712 1   32.446 ? 376  ASN B O   1 
ATOM   7052 C  CB  . ASN B 1 384 ? 40.86   -8.83   -21.787 1   35.55  ? 376  ASN B CB  1 
ATOM   7053 C  CG  . ASN B 1 384 ? 41.153  -10.254 -21.369 1   41.405 ? 376  ASN B CG  1 
ATOM   7054 O  OD1 . ASN B 1 384 ? 41.607  -11.046 -22.198 1   44.421 ? 376  ASN B OD1 1 
ATOM   7055 N  ND2 . ASN B 1 384 ? 40.959  -10.595 -20.102 1   35.937 ? 376  ASN B ND2 1 
ATOM   7056 N  N   . GLU B 1 385 ? 38.51   -6.365  -22.282 1   31.198 ? 377  GLU B N   1 
ATOM   7057 C  CA  . GLU B 1 385 ? 38.318  -4.948  -22.532 1   33.862 ? 377  GLU B CA  1 
ATOM   7058 C  C   . GLU B 1 385 ? 37.384  -4.429  -21.438 1   34.532 ? 377  GLU B C   1 
ATOM   7059 O  O   . GLU B 1 385 ? 36.35   -5.043  -21.187 1   30.343 ? 377  GLU B O   1 
ATOM   7060 C  CB  . GLU B 1 385 ? 37.666  -4.802  -23.911 1   35.941 ? 377  GLU B CB  1 
ATOM   7061 C  CG  . GLU B 1 385 ? 37.351  -3.357  -24.302 1   38.554 ? 377  GLU B CG  1 
ATOM   7062 C  CD  . GLU B 1 385 ? 36.799  -3.18   -25.71  1   45.871 ? 377  GLU B CD  1 
ATOM   7063 O  OE1 . GLU B 1 385 ? 37.622  -3.169  -26.644 1   57.004 ? 377  GLU B OE1 1 
ATOM   7064 O  OE2 . GLU B 1 385 ? 35.562  -3.066  -25.897 1   41.093 ? 377  GLU B OE2 1 
ATOM   7065 N  N   . GLN B 1 386 ? 37.742  -3.27   -20.876 1   30.01  ? 378  GLN B N   1 
ATOM   7066 C  CA  . GLN B 1 386 ? 36.93   -2.602  -19.88  1   30.766 ? 378  GLN B CA  1 
ATOM   7067 C  C   . GLN B 1 386 ? 35.514  -2.396  -20.424 1   29.189 ? 378  GLN B C   1 
ATOM   7068 O  O   . GLN B 1 386 ? 35.304  -2.04   -21.591 1   28.424 ? 378  GLN B O   1 
ATOM   7069 C  CB  . GLN B 1 386 ? 37.654  -1.338  -19.432 1   35.468 ? 378  GLN B CB  1 
ATOM   7070 C  CG  . GLN B 1 386 ? 36.892  -0.525  -18.386 1   32.204 ? 378  GLN B CG  1 
ATOM   7071 C  CD  . GLN B 1 386 ? 37.594  0.768   -18.055 1   38.46  ? 378  GLN B CD  1 
ATOM   7072 O  OE1 . GLN B 1 386 ? 38.63   0.776   -17.387 1   44.856 ? 378  GLN B OE1 1 
ATOM   7073 N  NE2 . GLN B 1 386 ? 37.038  1.863   -18.538 1   45.866 ? 378  GLN B NE2 1 
ATOM   7074 N  N   . LEU B 1 387 ? 34.531  -2.636  -19.546 1   27.306 ? 379  LEU B N   1 
ATOM   7075 C  CA  . LEU B 1 387 ? 33.129  -2.487  -19.884 1   24.636 ? 379  LEU B CA  1 
ATOM   7076 C  C   . LEU B 1 387 ? 32.844  -1.024  -20.2   1   25.109 ? 379  LEU B C   1 
ATOM   7077 O  O   . LEU B 1 387 ? 33.531  -0.132  -19.681 1   24.935 ? 379  LEU B O   1 
ATOM   7078 C  CB  . LEU B 1 387 ? 32.295  -2.947  -18.677 1   25.391 ? 379  LEU B CB  1 
ATOM   7079 C  CG  . LEU B 1 387 ? 32.146  -4.465  -18.517 1   24.748 ? 379  LEU B CG  1 
ATOM   7080 C  CD1 . LEU B 1 387 ? 31.426  -4.732  -17.175 1   24.551 ? 379  LEU B CD1 1 
ATOM   7081 C  CD2 . LEU B 1 387 ? 31.376  -5.121  -19.647 1   25.274 ? 379  LEU B CD2 1 
ATOM   7082 N  N   . PRO B 1 388 ? 31.824  -0.741  -21.048 1   25.832 ? 380  PRO B N   1 
ATOM   7083 C  CA  . PRO B 1 388 ? 31.33   0.612   -21.217 1   27.83  ? 380  PRO B CA  1 
ATOM   7084 C  C   . PRO B 1 388 ? 30.785  1.197   -19.917 1   30.248 ? 380  PRO B C   1 
ATOM   7085 O  O   . PRO B 1 388 ? 30.28   0.457   -19.078 1   29.617 ? 380  PRO B O   1 
ATOM   7086 C  CB  . PRO B 1 388 ? 30.299  0.495   -22.353 1   27.62  ? 380  PRO B CB  1 
ATOM   7087 C  CG  . PRO B 1 388 ? 29.846  -0.941  -22.244 1   29.341 ? 380  PRO B CG  1 
ATOM   7088 C  CD  . PRO B 1 388 ? 31.061  -1.727  -21.844 1   26.739 ? 380  PRO B CD  1 
ATOM   7089 N  N   . ASP B 1 389 ? 30.921  2.52    -19.751 1   30.324 ? 381  ASP B N   1 
ATOM   7090 C  CA  . ASP B 1 389 ? 30.297  3.201   -18.629 1   31.062 ? 381  ASP B CA  1 
ATOM   7091 C  C   . ASP B 1 389 ? 28.811  2.892   -18.591 1   27.491 ? 381  ASP B C   1 
ATOM   7092 O  O   . ASP B 1 389 ? 28.142  2.87    -19.637 1   26.682 ? 381  ASP B O   1 
ATOM   7093 C  CB  . ASP B 1 389 ? 30.512  4.704   -18.62  1   30.25  ? 381  ASP B CB  1 
ATOM   7094 C  CG  . ASP B 1 389 ? 31.945  5.172   -18.461 1   34.013 ? 381  ASP B CG  1 
ATOM   7095 O  OD1 . ASP B 1 389 ? 32.839  4.348   -18.135 1   29.287 ? 381  ASP B OD1 1 
ATOM   7096 O  OD2 . ASP B 1 389 ? 32.147  6.367   -18.681 1   34.683 ? 381  ASP B OD2 1 
ATOM   7097 N  N   . PRO B 1 390 ? 28.247  2.603   -17.388 1   28.626 ? 382  PRO B N   1 
ATOM   7098 C  CA  . PRO B 1 390 ? 26.832  2.278   -17.323 1   27.806 ? 382  PRO B CA  1 
ATOM   7099 C  C   . PRO B 1 390 ? 25.991  3.524   -17.62  1   26.505 ? 382  PRO B C   1 
ATOM   7100 O  O   . PRO B 1 390 ? 26.466  4.628   -17.382 1   26.117 ? 382  PRO B O   1 
ATOM   7101 C  CB  . PRO B 1 390 ? 26.677  1.732   -15.894 1   28.506 ? 382  PRO B CB  1 
ATOM   7102 C  CG  . PRO B 1 390 ? 27.74   2.487   -15.116 1   25.099 ? 382  PRO B CG  1 
ATOM   7103 C  CD  . PRO B 1 390 ? 28.923  2.518   -16.08  1   27.949 ? 382  PRO B CD  1 
ATOM   7104 N  N   . GLU B 1 391 ? 24.768  3.338   -18.12  1   26.685 ? 383  GLU B N   1 
ATOM   7105 C  CA  . GLU B 1 391 ? 23.88   4.477   -18.373 1   27.725 ? 383  GLU B CA  1 
ATOM   7106 C  C   . GLU B 1 391 ? 23.167  4.879   -17.079 1   27.52  ? 383  GLU B C   1 
ATOM   7107 O  O   . GLU B 1 391 ? 22.642  4.016   -16.376 1   27.761 ? 383  GLU B O   1 
ATOM   7108 C  CB  . GLU B 1 391 ? 22.915  4.006   -19.45  1   28.253 ? 383  GLU B CB  1 
ATOM   7109 C  CG  . GLU B 1 391 ? 21.856  5.041   -19.823 1   31.364 ? 383  GLU B CG  1 
ATOM   7110 C  CD  . GLU B 1 391 ? 20.807  4.527   -20.798 1   34.175 ? 383  GLU B CD  1 
ATOM   7111 O  OE1 . GLU B 1 391 ? 20.819  3.348   -21.227 1   37.033 ? 383  GLU B OE1 1 
ATOM   7112 O  OE2 . GLU B 1 391 ? 19.905  5.351   -21.117 1   41.559 ? 383  GLU B OE2 1 
ATOM   7113 N  N   . VAL B 1 392 ? 23.143  6.19    -16.783 1   27.098 ? 384  VAL B N   1 
ATOM   7114 C  CA  . VAL B 1 392 ? 22.433  6.677   -15.603 1   27.017 ? 384  VAL B CA  1 
ATOM   7115 C  C   . VAL B 1 392 ? 20.939  6.656   -15.932 1   30.234 ? 384  VAL B C   1 
ATOM   7116 O  O   . VAL B 1 392 ? 20.486  7.274   -16.91  1   27.077 ? 384  VAL B O   1 
ATOM   7117 C  CB  . VAL B 1 392 ? 22.947  8.045   -15.113 1   30.37  ? 384  VAL B CB  1 
ATOM   7118 C  CG1 . VAL B 1 392 ? 22.173  8.549   -13.904 1   30.96  ? 384  VAL B CG1 1 
ATOM   7119 C  CG2 . VAL B 1 392 ? 24.434  8.017   -14.782 1   30.228 ? 384  VAL B CG2 1 
ATOM   7120 N  N   . ILE B 1 393 ? 20.177  5.915   -15.106 1   26.116 ? 385  ILE B N   1 
ATOM   7121 C  CA  . ILE B 1 393 ? 18.745  5.762   -15.278 1   25.824 ? 385  ILE B CA  1 
ATOM   7122 C  C   . ILE B 1 393 ? 18.018  6.718   -14.339 1   28.484 ? 385  ILE B C   1 
ATOM   7123 O  O   . ILE B 1 393 ? 17.137  7.44    -14.781 1   32.078 ? 385  ILE B O   1 
ATOM   7124 C  CB  . ILE B 1 393 ? 18.313  4.284   -15.103 1   26.132 ? 385  ILE B CB  1 
ATOM   7125 C  CG1 . ILE B 1 393 ? 18.985  3.33    -16.129 1   25.553 ? 385  ILE B CG1 1 
ATOM   7126 C  CG2 . ILE B 1 393 ? 16.783  4.142   -15.112 1   27.024 ? 385  ILE B CG2 1 
ATOM   7127 C  CD1 . ILE B 1 393 ? 18.769  3.671   -17.606 1   27.271 ? 385  ILE B CD1 1 
ATOM   7128 N  N   . LEU B 1 394 ? 18.365  6.673   -13.054 1   26.044 ? 386  LEU B N   1 
ATOM   7129 C  CA  . LEU B 1 394 ? 17.932  7.668   -12.087 1   27.299 ? 386  LEU B CA  1 
ATOM   7130 C  C   . LEU B 1 394 ? 19.152  8.331   -11.465 1   29.66  ? 386  LEU B C   1 
ATOM   7131 O  O   . LEU B 1 394 ? 20.016  7.669   -10.88  1   27.601 ? 386  LEU B O   1 
ATOM   7132 C  CB  . LEU B 1 394 ? 17.042  7.068   -10.989 1   29.247 ? 386  LEU B CB  1 
ATOM   7133 C  CG  . LEU B 1 394 ? 15.795  6.28    -11.41  1   29.13  ? 386  LEU B CG  1 
ATOM   7134 C  CD1 . LEU B 1 394 ? 15.183  5.758   -10.104 1   28.94  ? 386  LEU B CD1 1 
ATOM   7135 C  CD2 . LEU B 1 394 ? 14.819  7.195   -12.118 1   31.365 ? 386  LEU B CD2 1 
ATOM   7136 N  N   . ASP B 1 395 ? 19.182  9.663   -11.573 1   28.887 ? 387  ASP B N   1 
ATOM   7137 C  CA  . ASP B 1 395 ? 20.233  10.463  -10.983 1   28.678 ? 387  ASP B CA  1 
ATOM   7138 C  C   . ASP B 1 395 ? 19.841  10.879  -9.568  1   30.254 ? 387  ASP B C   1 
ATOM   7139 O  O   . ASP B 1 395 ? 19.801  12.072  -9.224  1   30.634 ? 387  ASP B O   1 
ATOM   7140 C  CB  . ASP B 1 395 ? 20.629  11.624  -11.885 1   33.353 ? 387  ASP B CB  1 
ATOM   7141 C  CG  . ASP B 1 395 ? 21.934  12.287  -11.473 1   39.001 ? 387  ASP B CG  1 
ATOM   7142 O  OD1 . ASP B 1 395 ? 22.77   11.623  -10.807 1   33.575 ? 387  ASP B OD1 1 
ATOM   7143 O  OD2 . ASP B 1 395 ? 22.079  13.481  -11.763 1   50.256 ? 387  ASP B OD2 1 
ATOM   7144 N  N   . THR B 1 396 ? 19.533  9.887   -8.736  1   25.404 ? 388  THR B N   1 
ATOM   7145 C  CA  . THR B 1 396 ? 19.216  10.131  -7.342  1   27.209 ? 388  THR B CA  1 
ATOM   7146 C  C   . THR B 1 396 ? 19.681  8.895   -6.573  1   26.906 ? 388  THR B C   1 
ATOM   7147 O  O   . THR B 1 396 ? 19.699  7.79    -7.146  1   25.138 ? 388  THR B O   1 
ATOM   7148 C  CB  . THR B 1 396 ? 17.711  10.409  -7.163  1   29.661 ? 388  THR B CB  1 
ATOM   7149 O  OG1 . THR B 1 396 ? 17.566  11.033  -5.893  1   30.268 ? 388  THR B OG1 1 
ATOM   7150 C  CG2 . THR B 1 396 ? 16.81   9.185   -7.203  1   28.004 ? 388  THR B CG2 1 
ATOM   7151 N  N   . PRO B 1 397 ? 20.056  9.027   -5.283  1   26.465 ? 389  PRO B N   1 
ATOM   7152 C  CA  . PRO B 1 397 ? 20.355  7.852   -4.483  1   27.923 ? 389  PRO B CA  1 
ATOM   7153 C  C   . PRO B 1 397 ? 19.176  6.896   -4.482  1   24.736 ? 389  PRO B C   1 
ATOM   7154 O  O   . PRO B 1 397 ? 18.028  7.308   -4.322  1   24.627 ? 389  PRO B O   1 
ATOM   7155 C  CB  . PRO B 1 397 ? 20.75   8.413   -3.127  1   26.191 ? 389  PRO B CB  1 
ATOM   7156 C  CG  . PRO B 1 397 ? 21.249  9.839   -3.44   1   30.319 ? 389  PRO B CG  1 
ATOM   7157 C  CD  . PRO B 1 397 ? 20.315  10.281  -4.537  1   26.165 ? 389  PRO B CD  1 
ATOM   7158 N  N   . SER B 1 398 ? 19.5    5.629   -4.753  1   21.373 ? 390  SER B N   1 
ATOM   7159 C  CA  . SER B 1 398 ? 18.568  4.578   -5.125  1   22.935 ? 390  SER B CA  1 
ATOM   7160 C  C   . SER B 1 398 ? 19.102  3.304   -4.488  1   25.703 ? 390  SER B C   1 
ATOM   7161 O  O   . SER B 1 398 ? 20.305  3.051   -4.499  1   26.638 ? 390  SER B O   1 
ATOM   7162 C  CB  . SER B 1 398 ? 18.5    4.377   -6.621  1   22.768 ? 390  SER B CB  1 
ATOM   7163 O  OG  . SER B 1 398 ? 17.933  5.507   -7.27   1   26.163 ? 390  SER B OG  1 
ATOM   7164 N  N   . GLU B 1 399 ? 18.203  2.519   -3.893  1   25.545 ? 391  GLU B N   1 
ATOM   7165 C  CA  . GLU B 1 399 ? 18.631  1.248   -3.31   1   24.697 ? 391  GLU B CA  1 
ATOM   7166 C  C   . GLU B 1 399 ? 17.411  0.348   -3.224  1   22.434 ? 391  GLU B C   1 
ATOM   7167 O  O   . GLU B 1 399 ? 16.322  0.745   -3.615  1   21.885 ? 391  GLU B O   1 
ATOM   7168 C  CB  . GLU B 1 399 ? 19.474  1.436   -2.034  1   25.1   ? 391  GLU B CB  1 
ATOM   7169 C  CG  . GLU B 1 399 ? 20.902  0.892   -2.168  1   28.806 ? 391  GLU B CG  1 
ATOM   7170 C  CD  . GLU B 1 399 ? 20.848  -0.586  -2.5    1   28.378 ? 391  GLU B CD  1 
ATOM   7171 O  OE1 . GLU B 1 399 ? 20.32   -1.333  -1.668  1   30.508 ? 391  GLU B OE1 1 
ATOM   7172 O  OE2 . GLU B 1 399 ? 21.152  -1.003  -3.624  1   32.243 ? 391  GLU B OE2 1 
ATOM   7173 N  N   . PHE B 1 400 ? 17.64   -0.897  -2.801  1   22.467 ? 392  PHE B N   1 
ATOM   7174 C  CA  . PHE B 1 400 ? 16.621  -1.915  -2.593  1   20.663 ? 392  PHE B CA  1 
ATOM   7175 C  C   . PHE B 1 400 ? 15.639  -1.969  -3.749  1   21.701 ? 392  PHE B C   1 
ATOM   7176 O  O   . PHE B 1 400 ? 14.439  -1.859  -3.525  1   22.915 ? 392  PHE B O   1 
ATOM   7177 C  CB  . PHE B 1 400 ? 15.884  -1.718  -1.258  1   20.673 ? 392  PHE B CB  1 
ATOM   7178 C  CG  . PHE B 1 400 ? 16.825  -1.898  -0.073  1   25.277 ? 392  PHE B CG  1 
ATOM   7179 C  CD1 . PHE B 1 400 ? 17.361  -3.159  0.227   1   25.88  ? 392  PHE B CD1 1 
ATOM   7180 C  CD2 . PHE B 1 400 ? 17.125  -0.822  0.765   1   22.08  ? 392  PHE B CD2 1 
ATOM   7181 C  CE1 . PHE B 1 400 ? 18.203  -3.337  1.327   1   25.012 ? 392  PHE B CE1 1 
ATOM   7182 C  CE2 . PHE B 1 400 ? 17.946  -1.016  1.886   1   24.417 ? 392  PHE B CE2 1 
ATOM   7183 C  CZ  . PHE B 1 400 ? 18.495  -2.261  2.152   1   26.171 ? 392  PHE B CZ  1 
ATOM   7184 N  N   . PRO B 1 401 ? 16.097  -2.194  -5.006  1   20.086 ? 393  PRO B N   1 
ATOM   7185 C  CA  . PRO B 1 401 ? 15.147  -2.359  -6.092  1   22.156 ? 393  PRO B CA  1 
ATOM   7186 C  C   . PRO B 1 401 ? 14.529  -3.757  -6.121  1   21.696 ? 393  PRO B C   1 
ATOM   7187 O  O   . PRO B 1 401 ? 15.197  -4.747  -5.804  1   22.723 ? 393  PRO B O   1 
ATOM   7188 C  CB  . PRO B 1 401 ? 16.024  -2.11   -7.322  1   21.322 ? 393  PRO B CB  1 
ATOM   7189 C  CG  . PRO B 1 401 ? 17.385  -2.711  -6.904  1   22.647 ? 393  PRO B CG  1 
ATOM   7190 C  CD  . PRO B 1 401 ? 17.517  -2.283  -5.449  1   20.93  ? 393  PRO B CD  1 
ATOM   7191 N  N   . GLN B 1 402 ? 13.264  -3.831  -6.551  1   19.162 ? 394  GLN B N   1 
ATOM   7192 C  CA  . GLN B 1 402 ? 12.682  -5.126  -6.855  1   18.765 ? 394  GLN B CA  1 
ATOM   7193 C  C   . GLN B 1 402 ? 11.967  -5.001  -8.183  1   21.016 ? 394  GLN B C   1 
ATOM   7194 O  O   . GLN B 1 402 ? 11.805  -3.879  -8.691  1   23.915 ? 394  GLN B O   1 
ATOM   7195 C  CB  . GLN B 1 402 ? 11.662  -5.551  -5.798  1   21.611 ? 394  GLN B CB  1 
ATOM   7196 C  CG  . GLN B 1 402 ? 12.298  -5.874  -4.443  1   20.293 ? 394  GLN B CG  1 
ATOM   7197 C  CD  . GLN B 1 402 ? 11.574  -6.971  -3.679  1   23.267 ? 394  GLN B CD  1 
ATOM   7198 O  OE1 . GLN B 1 402 ? 10.517  -7.468  -4.087  1   24.718 ? 394  GLN B OE1 1 
ATOM   7199 N  NE2 . GLN B 1 402 ? 12.148  -7.361  -2.545  1   22.739 ? 394  GLN B NE2 1 
ATOM   7200 N  N   . ILE B 1 403 ? 11.555  -6.145  -8.72   1   21.993 ? 395  ILE B N   1 
ATOM   7201 C  CA  . ILE B 1 403 ? 10.842  -6.142  -10.003 1   23.372 ? 395  ILE B CA  1 
ATOM   7202 C  C   . ILE B 1 403 ? 9.509   -6.873  -9.832  1   24.05  ? 395  ILE B C   1 
ATOM   7203 O  O   . ILE B 1 403 ? 9.141   -7.296  -8.725  1   24.95  ? 395  ILE B O   1 
ATOM   7204 C  CB  . ILE B 1 403 ? 11.715  -6.746  -11.142 1   20.659 ? 395  ILE B CB  1 
ATOM   7205 C  CG1 . ILE B 1 403 ? 11.957  -8.285  -10.95  1   20.669 ? 395  ILE B CG1 1 
ATOM   7206 C  CG2 . ILE B 1 403 ? 13.016  -5.966  -11.308 1   22.012 ? 395  ILE B CG2 1 
ATOM   7207 C  CD1 . ILE B 1 403 ? 12.228  -9.079  -12.241 1   22.384 ? 395  ILE B CD1 1 
ATOM   7208 N  N   . ASP B 1 404 ? 8.751   -6.979  -10.934 1   23.061 ? 396  ASP B N   1 
ATOM   7209 C  CA  . ASP B 1 404 ? 7.635   -7.919  -11.009 1   22.968 ? 396  ASP B CA  1 
ATOM   7210 C  C   . ASP B 1 404 ? 8.216   -9.321  -11.215 1   24.579 ? 396  ASP B C   1 
ATOM   7211 O  O   . ASP B 1 404 ? 8.703   -9.644  -12.301 1   25.24  ? 396  ASP B O   1 
ATOM   7212 C  CB  . ASP B 1 404 ? 6.696   -7.478  -12.13  1   24.311 ? 396  ASP B CB  1 
ATOM   7213 C  CG  . ASP B 1 404 ? 5.443   -8.311  -12.35  1   25.785 ? 396  ASP B CG  1 
ATOM   7214 O  OD1 . ASP B 1 404 ? 5.384   -9.491  -11.875 1   24.503 ? 396  ASP B OD1 1 
ATOM   7215 O  OD2 . ASP B 1 404 ? 4.516   -7.755  -13.022 1   28.121 ? 396  ASP B OD2 1 
ATOM   7216 N  N   . ASN B 1 405 ? 8.158   -10.159 -10.161 1   24.085 ? 397  ASN B N   1 
ATOM   7217 C  CA  . ASN B 1 405 ? 8.83    -11.464 -10.11  1   25.299 ? 397  ASN B CA  1 
ATOM   7218 C  C   . ASN B 1 405 ? 8.307   -12.481 -11.129 1   27.617 ? 397  ASN B C   1 
ATOM   7219 O  O   . ASN B 1 405 ? 8.95    -13.501 -11.362 1   24.914 ? 397  ASN B O   1 
ATOM   7220 C  CB  . ASN B 1 405 ? 8.838   -12.049 -8.699  1   29.627 ? 397  ASN B CB  1 
ATOM   7221 C  CG  . ASN B 1 405 ? 9.772   -11.241 -7.818  1   32.972 ? 397  ASN B CG  1 
ATOM   7222 O  OD1 . ASN B 1 405 ? 9.483   -11.063 -6.637  1   40.501 ? 397  ASN B OD1 1 
ATOM   7223 N  ND2 . ASN B 1 405 ? 10.867  -10.722 -8.363  1   37.625 ? 397  ASN B ND2 1 
ATOM   7224 N  N   . ARG B 1 406 ? 7.155   -12.203 -11.759 1   25.974 ? 398  ARG B N   1 
ATOM   7225 C  CA  . ARG B 1 406 ? 6.713   -12.955 -12.922 1   26.047 ? 398  ARG B CA  1 
ATOM   7226 C  C   . ARG B 1 406 ? 7.681   -12.858 -14.113 1   26.419 ? 398  ARG B C   1 
ATOM   7227 O  O   . ARG B 1 406 ? 7.56    -13.659 -15.053 1   28.759 ? 398  ARG B O   1 
ATOM   7228 C  CB  . ARG B 1 406 ? 5.299   -12.533 -13.35  1   25.076 ? 398  ARG B CB  1 
ATOM   7229 C  CG  . ARG B 1 406 ? 4.333   -12.794 -12.206 1   24.894 ? 398  ARG B CG  1 
ATOM   7230 C  CD  . ARG B 1 406 ? 2.953   -12.294 -12.65  1   25.294 ? 398  ARG B CD  1 
ATOM   7231 N  NE  . ARG B 1 406 ? 3       -10.842 -12.905 1   24.341 ? 398  ARG B NE  1 
ATOM   7232 C  CZ  . ARG B 1 406 ? 2.036   -10.143 -13.516 1   26.506 ? 398  ARG B CZ  1 
ATOM   7233 N  NH1 . ARG B 1 406 ? 0.953   -10.797 -13.894 1   26.42  ? 398  ARG B NH1 1 
ATOM   7234 N  NH2 . ARG B 1 406 ? 2.145   -8.826  -13.69  1   23.402 ? 398  ARG B NH2 1 
ATOM   7235 N  N   . PHE B 1 407 ? 8.615   -11.887 -14.07  1   23.92  ? 399  PHE B N   1 
ATOM   7236 C  CA  . PHE B 1 407 ? 9.55    -11.606 -15.154 1   25.469 ? 399  PHE B CA  1 
ATOM   7237 C  C   . PHE B 1 407 ? 10.996  -11.871 -14.716 1   27.625 ? 399  PHE B C   1 
ATOM   7238 O  O   . PHE B 1 407 ? 11.912  -11.372 -15.348 1   25.023 ? 399  PHE B O   1 
ATOM   7239 C  CB  . PHE B 1 407 ? 9.363   -10.168 -15.66  1   27.188 ? 399  PHE B CB  1 
ATOM   7240 C  CG  . PHE B 1 407 ? 7.978   -9.992  -16.27  1   28.591 ? 399  PHE B CG  1 
ATOM   7241 C  CD1 . PHE B 1 407 ? 6.868   -9.7    -15.465 1   30.448 ? 399  PHE B CD1 1 
ATOM   7242 C  CD2 . PHE B 1 407 ? 7.789   -10.14  -17.653 1   33.565 ? 399  PHE B CD2 1 
ATOM   7243 C  CE1 . PHE B 1 407 ? 5.578   -9.602  -16.019 1   30.833 ? 399  PHE B CE1 1 
ATOM   7244 C  CE2 . PHE B 1 407 ? 6.5     -10.012 -18.214 1   33.507 ? 399  PHE B CE2 1 
ATOM   7245 C  CZ  . PHE B 1 407 ? 5.404   -9.741  -17.394 1   33.656 ? 399  PHE B CZ  1 
ATOM   7246 N  N   . MET B 1 408 ? 11.199  -12.673 -13.657 1   24.382 ? 400  MET B N   1 
ATOM   7247 C  CA  . MET B 1 408 ? 12.546  -12.947 -13.181 1   24.345 ? 400  MET B CA  1 
ATOM   7248 C  C   . MET B 1 408 ? 13.264  -13.892 -14.144 1   23.64  ? 400  MET B C   1 
ATOM   7249 O  O   . MET B 1 408 ? 12.751  -14.959 -14.449 1   25.941 ? 400  MET B O   1 
ATOM   7250 C  CB  . MET B 1 408 ? 12.513  -13.489 -11.738 1   23.598 ? 400  MET B CB  1 
ATOM   7251 C  CG  . MET B 1 408 ? 13.87   -13.917 -11.183 1   21.811 ? 400  MET B CG  1 
ATOM   7252 S  SD  . MET B 1 408 ? 15.128  -12.644 -11.335 1   25.492 ? 400  MET B SD  1 
ATOM   7253 C  CE  . MET B 1 408 ? 14.562  -11.538 -10.035 1   22.618 ? 400  MET B CE  1 
ATOM   7254 N  N   . GLY B 1 409 ? 14.445  -13.466 -14.613 1   22.537 ? 401  GLY B N   1 
ATOM   7255 C  CA  . GLY B 1 409 ? 15.268  -14.284 -15.491 1   21.072 ? 401  GLY B CA  1 
ATOM   7256 C  C   . GLY B 1 409 ? 14.873  -14.138 -16.96  1   25.986 ? 401  GLY B C   1 
ATOM   7257 O  O   . GLY B 1 409 ? 15.378  -14.899 -17.792 1   27.582 ? 401  GLY B O   1 
ATOM   7258 N  N   . VAL B 1 410 ? 13.973  -13.189 -17.259 1   25.533 ? 402  VAL B N   1 
ATOM   7259 C  CA  . VAL B 1 410 ? 13.574  -12.882 -18.635 1   28.229 ? 402  VAL B CA  1 
ATOM   7260 C  C   . VAL B 1 410 ? 13.554  -11.369 -18.775 1   27.542 ? 402  VAL B C   1 
ATOM   7261 O  O   . VAL B 1 410 ? 13.69   -10.666 -17.774 1   27.035 ? 402  VAL B O   1 
ATOM   7262 C  CB  . VAL B 1 410 ? 12.21   -13.496 -19.026 1   25.749 ? 402  VAL B CB  1 
ATOM   7263 C  CG1 . VAL B 1 410 ? 12.281  -15.021 -19.11  1   26.409 ? 402  VAL B CG1 1 
ATOM   7264 C  CG2 . VAL B 1 410 ? 11.044  -13.006 -18.158 1   25.877 ? 402  VAL B CG2 1 
ATOM   7265 N  N   . GLU B 1 411 ? 13.324  -10.873 -20.008 1   24.781 ? 403  GLU B N   1 
ATOM   7266 C  CA  . GLU B 1 411 ? 13.191  -9.436  -20.188 1   25.001 ? 403  GLU B CA  1 
ATOM   7267 C  C   . GLU B 1 411 ? 12.12   -8.858  -19.246 1   23.582 ? 403  GLU B C   1 
ATOM   7268 O  O   . GLU B 1 411 ? 11.006  -9.396  -19.163 1   27.052 ? 403  GLU B O   1 
ATOM   7269 C  CB  . GLU B 1 411 ? 12.893  -9.157  -21.667 1   24.37  ? 403  GLU B CB  1 
ATOM   7270 C  CG  . GLU B 1 411 ? 12.784  -7.651  -21.857 1   28.567 ? 403  GLU B CG  1 
ATOM   7271 C  CD  . GLU B 1 411 ? 12.625  -7.174  -23.284 1   34.662 ? 403  GLU B CD  1 
ATOM   7272 O  OE1 . GLU B 1 411 ? 12.623  -8.031  -24.179 1   38.271 ? 403  GLU B OE1 1 
ATOM   7273 O  OE2 . GLU B 1 411 ? 12.545  -5.958  -23.469 1   32.53  ? 403  GLU B OE2 1 
ATOM   7274 N  N   . TYR B 1 412 ? 12.463  -7.751  -18.57  1   24.25  ? 404  TYR B N   1 
ATOM   7275 C  CA  . TYR B 1 412 ? 11.583  -7.088  -17.621 1   25.106 ? 404  TYR B CA  1 
ATOM   7276 C  C   . TYR B 1 412 ? 11.661  -5.604  -17.927 1   23.654 ? 404  TYR B C   1 
ATOM   7277 O  O   . TYR B 1 412 ? 12.615  -5.172  -18.57  1   27.836 ? 404  TYR B O   1 
ATOM   7278 C  CB  . TYR B 1 412 ? 11.96   -7.45   -16.172 1   24.706 ? 404  TYR B CB  1 
ATOM   7279 C  CG  . TYR B 1 412 ? 13.153  -6.651  -15.681 1   23.516 ? 404  TYR B CG  1 
ATOM   7280 C  CD1 . TYR B 1 412 ? 14.466  -7.043  -15.998 1   23.183 ? 404  TYR B CD1 1 
ATOM   7281 C  CD2 . TYR B 1 412 ? 12.968  -5.512  -14.882 1   25.366 ? 404  TYR B CD2 1 
ATOM   7282 C  CE1 . TYR B 1 412 ? 15.569  -6.287  -15.589 1   24.258 ? 404  TYR B CE1 1 
ATOM   7283 C  CE2 . TYR B 1 412 ? 14.066  -4.769  -14.444 1   23.511 ? 404  TYR B CE2 1 
ATOM   7284 C  CZ  . TYR B 1 412 ? 15.362  -5.153  -14.807 1   22.396 ? 404  TYR B CZ  1 
ATOM   7285 O  OH  . TYR B 1 412 ? 16.428  -4.384  -14.426 1   23.685 ? 404  TYR B OH  1 
ATOM   7286 N  N   . SER B 1 413 ? 10.664  -4.832  -17.44  1   22.693 ? 405  SER B N   1 
ATOM   7287 C  CA  . SER B 1 413 ? 10.582  -3.399  -17.674 1   22.834 ? 405  SER B CA  1 
ATOM   7288 C  C   . SER B 1 413 ? 10.36   -2.612  -16.376 1   22.652 ? 405  SER B C   1 
ATOM   7289 O  O   . SER B 1 413 ? 10.989  -1.578  -16.192 1   27.4   ? 405  SER B O   1 
ATOM   7290 C  CB  . SER B 1 413 ? 9.445   -3.16   -18.681 1   27.371 ? 405  SER B CB  1 
ATOM   7291 O  OG  . SER B 1 413 ? 9.253   -1.767  -18.821 1   28.045 ? 405  SER B OG  1 
ATOM   7292 N  N   . SER B 1 414 ? 9.464   -3.105  -15.49  1   24.346 ? 406  SER B N   1 
ATOM   7293 C  CA  . SER B 1 414 ? 9.151   -2.457  -14.216 1   23.817 ? 406  SER B CA  1 
ATOM   7294 C  C   . SER B 1 414 ? 10.255  -2.696  -13.183 1   23.28  ? 406  SER B C   1 
ATOM   7295 O  O   . SER B 1 414 ? 10.671  -3.833  -12.981 1   24.817 ? 406  SER B O   1 
ATOM   7296 C  CB  . SER B 1 414 ? 7.816   -2.889  -13.654 1   26.144 ? 406  SER B CB  1 
ATOM   7297 O  OG  . SER B 1 414 ? 6.748   -2.126  -14.221 1   25.422 ? 406  SER B OG  1 
ATOM   7298 N  N   . ALA B 1 415 ? 10.699  -1.603  -12.542 1   23.302 ? 407  ALA B N   1 
ATOM   7299 C  CA  . ALA B 1 415 ? 11.466  -1.704  -11.294 1   22.976 ? 407  ALA B CA  1 
ATOM   7300 C  C   . ALA B 1 415 ? 10.832  -0.805  -10.237 1   24.154 ? 407  ALA B C   1 
ATOM   7301 O  O   . ALA B 1 415 ? 10.371  0.295   -10.542 1   23.239 ? 407  ALA B O   1 
ATOM   7302 C  CB  . ALA B 1 415 ? 12.904  -1.298  -11.533 1   23.433 ? 407  ALA B CB  1 
ATOM   7303 N  N   . PHE B 1 416 ? 10.861  -1.28   -8.993  1   22.515 ? 408  PHE B N   1 
ATOM   7304 C  CA  . PHE B 1 416 ? 10.314  -0.582  -7.85   1   21.848 ? 408  PHE B CA  1 
ATOM   7305 C  C   . PHE B 1 416 ? 11.484  -0.311  -6.937  1   22.285 ? 408  PHE B C   1 
ATOM   7306 O  O   . PHE B 1 416 ? 12.155  -1.251  -6.549  1   22.941 ? 408  PHE B O   1 
ATOM   7307 C  CB  . PHE B 1 416 ? 9.262   -1.439  -7.13   1   20.69  ? 408  PHE B CB  1 
ATOM   7308 C  CG  . PHE B 1 416 ? 8.16    -1.873  -8.075  1   24.138 ? 408  PHE B CG  1 
ATOM   7309 C  CD1 . PHE B 1 416 ? 7.145   -0.975  -8.426  1   23.776 ? 408  PHE B CD1 1 
ATOM   7310 C  CD2 . PHE B 1 416 ? 8.161   -3.159  -8.625  1   22.17  ? 408  PHE B CD2 1 
ATOM   7311 C  CE1 . PHE B 1 416 ? 6.136   -1.371  -9.315  1   24.793 ? 408  PHE B CE1 1 
ATOM   7312 C  CE2 . PHE B 1 416 ? 7.169   -3.531  -9.535  1   24.539 ? 408  PHE B CE2 1 
ATOM   7313 C  CZ  . PHE B 1 416 ? 6.141   -2.646  -9.848  1   23.092 ? 408  PHE B CZ  1 
ATOM   7314 N  N   . ILE B 1 417 ? 11.776  0.979   -6.728  1   21.481 ? 409  ILE B N   1 
ATOM   7315 C  CA  . ILE B 1 417 ? 13.093  1.364   -6.24   1   22.92  ? 409  ILE B CA  1 
ATOM   7316 C  C   . ILE B 1 417 ? 12.887  2.235   -5.021  1   23.614 ? 409  ILE B C   1 
ATOM   7317 O  O   . ILE B 1 417 ? 12.04   3.132   -5.031  1   23.658 ? 409  ILE B O   1 
ATOM   7318 C  CB  . ILE B 1 417 ? 13.918  2.062   -7.337  1   21.463 ? 409  ILE B CB  1 
ATOM   7319 C  CG1 . ILE B 1 417 ? 13.958  1.184   -8.62   1   22.521 ? 409  ILE B CG1 1 
ATOM   7320 C  CG2 . ILE B 1 417 ? 15.333  2.337   -6.836  1   24.336 ? 409  ILE B CG2 1 
ATOM   7321 C  CD1 . ILE B 1 417 ? 14.419  1.917   -9.871  1   27.145 ? 409  ILE B CD1 1 
ATOM   7322 N  N   . ASN B 1 418 ? 13.669  1.946   -3.97   1   22.069 ? 410  ASN B N   1 
ATOM   7323 C  CA  . ASN B 1 418 ? 13.681  2.778   -2.786  1   23.131 ? 410  ASN B CA  1 
ATOM   7324 C  C   . ASN B 1 418 ? 14.611  3.946   -3.121  1   21.816 ? 410  ASN B C   1 
ATOM   7325 O  O   . ASN B 1 418 ? 15.737  3.729   -3.572  1   23.685 ? 410  ASN B O   1 
ATOM   7326 C  CB  . ASN B 1 418 ? 14.215  1.921   -1.63   1   23.17  ? 410  ASN B CB  1 
ATOM   7327 C  CG  . ASN B 1 418 ? 13.845  2.332   -0.23   1   23.41  ? 410  ASN B CG  1 
ATOM   7328 O  OD1 . ASN B 1 418 ? 13.067  3.283   0.022   1   26.068 ? 410  ASN B OD1 1 
ATOM   7329 N  ND2 . ASN B 1 418 ? 14.375  1.56    0.697   1   20.186 ? 410  ASN B ND2 1 
ATOM   7330 N  N   . VAL B 1 419 ? 14.166  5.186   -2.869  1   22.935 ? 411  VAL B N   1 
ATOM   7331 C  CA  . VAL B 1 419 ? 14.892  6.357   -3.346  1   23.691 ? 411  VAL B CA  1 
ATOM   7332 C  C   . VAL B 1 419 ? 14.978  7.457   -2.28   1   27.027 ? 411  VAL B C   1 
ATOM   7333 O  O   . VAL B 1 419 ? 14.106  7.59    -1.403  1   23.767 ? 411  VAL B O   1 
ATOM   7334 C  CB  . VAL B 1 419 ? 14.285  6.919   -4.651  1   25.469 ? 411  VAL B CB  1 
ATOM   7335 C  CG1 . VAL B 1 419 ? 14.441  5.965   -5.831  1   24.311 ? 411  VAL B CG1 1 
ATOM   7336 C  CG2 . VAL B 1 419 ? 12.825  7.345   -4.465  1   26.28  ? 411  VAL B CG2 1 
ATOM   7337 N  N   . PHE B 1 420 ? 16.035  8.288   -2.402  1   27.007 ? 412  PHE B N   1 
ATOM   7338 C  CA  . PHE B 1 420 ? 16.036  9.642   -1.847  1   26.879 ? 412  PHE B CA  1 
ATOM   7339 C  C   . PHE B 1 420 ? 15.192  10.463  -2.829  1   26.701 ? 412  PHE B C   1 
ATOM   7340 O  O   . PHE B 1 420 ? 15.527  10.552  -4.019  1   26.061 ? 412  PHE B O   1 
ATOM   7341 C  CB  . PHE B 1 420 ? 17.45   10.256  -1.812  1   27.587 ? 412  PHE B CB  1 
ATOM   7342 C  CG  . PHE B 1 420 ? 18.454  9.748   -0.773  1   29.019 ? 412  PHE B CG  1 
ATOM   7343 C  CD1 . PHE B 1 420 ? 18.515  8.39    -0.405  1   28.101 ? 412  PHE B CD1 1 
ATOM   7344 C  CD2 . PHE B 1 420 ? 19.367  10.626  -0.178  1   27.824 ? 412  PHE B CD2 1 
ATOM   7345 C  CE1 . PHE B 1 420 ? 19.451  7.933   0.525   1   24.856 ? 412  PHE B CE1 1 
ATOM   7346 C  CE2 . PHE B 1 420 ? 20.34   10.155  0.735   1   30.774 ? 412  PHE B CE2 1 
ATOM   7347 C  CZ  . PHE B 1 420 ? 20.375  8.82    1.082   1   27.851 ? 412  PHE B CZ  1 
ATOM   7348 N  N   . VAL B 1 421 ? 14.082  11.047  -2.357  1   30.814 ? 413  VAL B N   1 
ATOM   7349 C  CA  . VAL B 1 421 ? 13.19   11.754  -3.276  1   30.064 ? 413  VAL B CA  1 
ATOM   7350 C  C   . VAL B 1 421 ? 13.901  13.015  -3.798  1   25.838 ? 413  VAL B C   1 
ATOM   7351 O  O   . VAL B 1 421 ? 14.387  13.803  -2.984  1   27.165 ? 413  VAL B O   1 
ATOM   7352 C  CB  . VAL B 1 421 ? 11.773  12.03   -2.723  1   31.177 ? 413  VAL B CB  1 
ATOM   7353 C  CG1 . VAL B 1 421 ? 10.929  12.795  -3.737  1   32.372 ? 413  VAL B CG1 1 
ATOM   7354 C  CG2 . VAL B 1 421 ? 11.06   10.715  -2.408  1   26.667 ? 413  VAL B CG2 1 
ATOM   7355 N  N   . PRO B 1 422 ? 14.039  13.206  -5.139  1   29.928 ? 414  PRO B N   1 
ATOM   7356 C  CA  . PRO B 1 422 ? 14.67   14.421  -5.669  1   31.349 ? 414  PRO B CA  1 
ATOM   7357 C  C   . PRO B 1 422 ? 14.058  15.686  -5.086  1   34.911 ? 414  PRO B C   1 
ATOM   7358 O  O   . PRO B 1 422 ? 12.832  15.776  -5.004  1   33.023 ? 414  PRO B O   1 
ATOM   7359 C  CB  . PRO B 1 422 ? 14.535  14.334  -7.199  1   28.294 ? 414  PRO B CB  1 
ATOM   7360 C  CG  . PRO B 1 422 ? 14.228  12.882  -7.484  1   28.216 ? 414  PRO B CG  1 
ATOM   7361 C  CD  . PRO B 1 422 ? 13.662  12.26   -6.213  1   28.96  ? 414  PRO B CD  1 
ATOM   7362 N  N   . ASP B 1 423 ? 14.952  16.549  -4.572  1   36.291 ? 415  ASP B N   1 
ATOM   7363 C  CA  . ASP B 1 423 ? 14.676  17.872  -4.025  1   39.72  ? 415  ASP B CA  1 
ATOM   7364 C  C   . ASP B 1 423 ? 14.013  17.806  -2.651  1   37.807 ? 415  ASP B C   1 
ATOM   7365 O  O   . ASP B 1 423 ? 13.643  18.849  -2.132  1   36.497 ? 415  ASP B O   1 
ATOM   7366 C  CB  . ASP B 1 423 ? 13.931  18.768  -5.014  1   39.499 ? 415  ASP B CB  1 
ATOM   7367 C  CG  . ASP B 1 423 ? 14.662  19.012  -6.328  1   44.808 ? 415  ASP B CG  1 
ATOM   7368 O  OD1 . ASP B 1 423 ? 15.857  19.368  -6.273  1   47.804 ? 415  ASP B OD1 1 
ATOM   7369 O  OD2 . ASP B 1 423 ? 14.047  18.805  -7.385  1   45.758 ? 415  ASP B OD2 1 
ATOM   7370 N  N   . ARG B 1 424 ? 13.865  16.609  -2.057  1   33.419 ? 416  ARG B N   1 
ATOM   7371 C  CA  . ARG B 1 424 ? 13.088  16.441  -0.834  1   33.808 ? 416  ARG B CA  1 
ATOM   7372 C  C   . ARG B 1 424 ? 13.766  15.407  0.06    1   35.403 ? 416  ARG B C   1 
ATOM   7373 O  O   . ARG B 1 424 ? 13.109  14.638  0.744   1   36.608 ? 416  ARG B O   1 
ATOM   7374 C  CB  . ARG B 1 424 ? 11.65   15.989  -1.135  1   33.132 ? 416  ARG B CB  1 
ATOM   7375 C  CG  . ARG B 1 424 ? 10.824  16.686  -2.206  1   36.453 ? 416  ARG B CG  1 
ATOM   7376 C  CD  . ARG B 1 424 ? 9.401   16.106  -2.27   1   34.207 ? 416  ARG B CD  1 
ATOM   7377 N  NE  . ARG B 1 424 ? 8.579   16.458  -1.105  1   37.605 ? 416  ARG B NE  1 
ATOM   7378 C  CZ  . ARG B 1 424 ? 7.261   16.247  -1.017  1   35.94  ? 416  ARG B CZ  1 
ATOM   7379 N  NH1 . ARG B 1 424 ? 6.635   15.498  -1.908  1   38.482 ? 416  ARG B NH1 1 
ATOM   7380 N  NH2 . ARG B 1 424 ? 6.578   16.743  0.009   1   38.391 ? 416  ARG B NH2 1 
ATOM   7381 N  N   . SER B 1 425 ? 15.101  15.449  0.099   1   33.265 ? 417  SER B N   1 
ATOM   7382 C  CA  . SER B 1 425 ? 15.917  14.448  0.777   1   34.591 ? 417  SER B CA  1 
ATOM   7383 C  C   . SER B 1 425 ? 17.271  15.081  1.026   1   38.49  ? 417  SER B C   1 
ATOM   7384 O  O   . SER B 1 425 ? 17.586  16.099  0.397   1   34.219 ? 417  SER B O   1 
ATOM   7385 C  CB  . SER B 1 425 ? 16.041  13.183  -0.034  1   35.403 ? 417  SER B CB  1 
ATOM   7386 O  OG  . SER B 1 425 ? 16.525  13.431  -1.349  1   32.596 ? 417  SER B OG  1 
ATOM   7387 N  N   . ASP B 1 426 ? 18.075  14.462  1.891   1   38.065 ? 418  ASP B N   1 
ATOM   7388 C  CA  . ASP B 1 426 ? 19.27   15.177  2.314   1   43.416 ? 418  ASP B CA  1 
ATOM   7389 C  C   . ASP B 1 426 ? 20.307  15.287  1.172   1   56.538 ? 418  ASP B C   1 
ATOM   7390 O  O   . ASP B 1 426 ? 20.544  16.394  0.67    1   83.698 ? 418  ASP B O   1 
ATOM   7391 C  CB  . ASP B 1 426 ? 19.518  14.927  3.79    1   36.793 ? 418  ASP B CB  1 
ATOM   7392 C  CG  . ASP B 1 426 ? 20.846  15.446  4.317   1   39.33  ? 418  ASP B CG  1 
ATOM   7393 O  OD1 . ASP B 1 426 ? 21.713  15.815  3.494   1   41.206 ? 418  ASP B OD1 1 
ATOM   7394 O  OD2 . ASP B 1 426 ? 20.991  15.435  5.539   1   41.528 ? 418  ASP B OD2 1 
ATOM   7395 N  N   . GLY B 1 427 ? 20.873  14.156  0.722   1   43.072 ? 419  GLY B N   1 
ATOM   7396 C  CA  . GLY B 1 427 ? 21.97   14.053  -0.248  1   37.449 ? 419  GLY B CA  1 
ATOM   7397 C  C   . GLY B 1 427 ? 23.285  13.621  0.433   1   36.442 ? 419  GLY B C   1 
ATOM   7398 O  O   . GLY B 1 427 ? 24.018  12.75   -0.059  1   38.713 ? 419  GLY B O   1 
ATOM   7399 N  N   . ASN B 1 428 ? 23.526  14.198  1.616   1   32.566 ? 420  ASN B N   1 
ATOM   7400 C  CA  . ASN B 1 428 ? 24.724  13.948  2.405   1   38.678 ? 420  ASN B CA  1 
ATOM   7401 C  C   . ASN B 1 428 ? 24.578  12.746  3.345   1   36.463 ? 420  ASN B C   1 
ATOM   7402 O  O   . ASN B 1 428 ? 25.559  12.356  3.982   1   31.169 ? 420  ASN B O   1 
ATOM   7403 C  CB  . ASN B 1 428 ? 25.24   15.209  3.097   1   39.992 ? 420  ASN B CB  1 
ATOM   7404 C  CG  . ASN B 1 428 ? 26.719  15.086  3.387   1   48.728 ? 420  ASN B CG  1 
ATOM   7405 O  OD1 . ASN B 1 428 ? 27.127  15.189  4.551   1   54.33  ? 420  ASN B OD1 1 
ATOM   7406 N  ND2 . ASN B 1 428 ? 27.522  14.818  2.364   1   45.114 ? 420  ASN B ND2 1 
ATOM   7407 N  N   . LYS B 1 429 ? 23.372  12.158  3.414   1   33.151 ? 421  LYS B N   1 
ATOM   7408 C  CA  . LYS B 1 429 ? 23.18   10.936  4.196   1   32.841 ? 421  LYS B CA  1 
ATOM   7409 C  C   . LYS B 1 429 ? 23.745  9.747   3.422   1   29.304 ? 421  LYS B C   1 
ATOM   7410 O  O   . LYS B 1 429 ? 23.597  9.668   2.187   1   27.734 ? 421  LYS B O   1 
ATOM   7411 C  CB  . LYS B 1 429 ? 21.685  10.682  4.473   1   33.726 ? 421  LYS B CB  1 
ATOM   7412 C  CG  . LYS B 1 429 ? 21.165  11.659  5.502   1   36.327 ? 421  LYS B CG  1 
ATOM   7413 C  CD  . LYS B 1 429 ? 19.82   11.376  6.129   1   44.644 ? 421  LYS B CD  1 
ATOM   7414 C  CE  . LYS B 1 429 ? 19.511  12.411  7.161   1   47.114 ? 421  LYS B CE  1 
ATOM   7415 N  NZ  . LYS B 1 429 ? 18.254  11.966  7.76    1   58.603 ? 421  LYS B NZ  1 
ATOM   7416 N  N   . ASN B 1 430 ? 24.329  8.8     4.18    1   26.538 ? 422  ASN B N   1 
ATOM   7417 C  CA  . ASN B 1 430 ? 24.608  7.453   3.7     1   27.133 ? 422  ASN B CA  1 
ATOM   7418 C  C   . ASN B 1 430 ? 23.374  6.908   2.976   1   26.843 ? 422  ASN B C   1 
ATOM   7419 O  O   . ASN B 1 430 ? 22.246  7.198   3.382   1   25.568 ? 422  ASN B O   1 
ATOM   7420 C  CB  . ASN B 1 430 ? 25.137  6.583   4.845   1   25.298 ? 422  ASN B CB  1 
ATOM   7421 C  CG  . ASN B 1 430 ? 25.331  5.151   4.415   1   26.682 ? 422  ASN B CG  1 
ATOM   7422 O  OD1 . ASN B 1 430 ? 24.39   4.338   4.56    1   26.83  ? 422  ASN B OD1 1 
ATOM   7423 N  ND2 . ASN B 1 430 ? 26.516  4.843   3.877   1   24.617 ? 422  ASN B ND2 1 
ATOM   7424 N  N   . VAL B 1 431 ? 23.608  6.165   1.873   1   24.942 ? 423  VAL B N   1 
ATOM   7425 C  CA  . VAL B 1 431 ? 22.569  5.69    0.961   1   23.906 ? 423  VAL B CA  1 
ATOM   7426 C  C   . VAL B 1 431 ? 21.472  4.902   1.701   1   25.879 ? 423  VAL B C   1 
ATOM   7427 O  O   . VAL B 1 431 ? 20.332  4.909   1.267   1   25.722 ? 423  VAL B O   1 
ATOM   7428 C  CB  . VAL B 1 431 ? 23.136  4.91    -0.245  1   25.347 ? 423  VAL B CB  1 
ATOM   7429 C  CG1 . VAL B 1 431 ? 23.768  3.564   0.166   1   24.514 ? 423  VAL B CG1 1 
ATOM   7430 C  CG2 . VAL B 1 431 ? 22.077  4.678   -1.316  1   23.949 ? 423  VAL B CG2 1 
ATOM   7431 N  N   . PHE B 1 432 ? 21.822  4.23    2.803   1   26.055 ? 424  PHE B N   1 
ATOM   7432 C  CA  . PHE B 1 432 ? 20.831  3.416   3.513   1   24.619 ? 424  PHE B CA  1 
ATOM   7433 C  C   . PHE B 1 432 ? 20.031  4.241   4.515   1   26.609 ? 424  PHE B C   1 
ATOM   7434 O  O   . PHE B 1 432 ? 19.079  3.719   5.109   1   25.758 ? 424  PHE B O   1 
ATOM   7435 C  CB  . PHE B 1 432 ? 21.531  2.254   4.244   1   26.342 ? 424  PHE B CB  1 
ATOM   7436 C  CG  . PHE B 1 432 ? 22.167  1.285   3.256   1   27.387 ? 424  PHE B CG  1 
ATOM   7437 C  CD1 . PHE B 1 432 ? 21.363  0.442   2.468   1   27.184 ? 424  PHE B CD1 1 
ATOM   7438 C  CD2 . PHE B 1 432 ? 23.561  1.248   3.097   1   26.848 ? 424  PHE B CD2 1 
ATOM   7439 C  CE1 . PHE B 1 432 ? 21.938  -0.424  1.54    1   29.341 ? 424  PHE B CE1 1 
ATOM   7440 C  CE2 . PHE B 1 432 ? 24.128  0.378   2.171   1   27.761 ? 424  PHE B CE2 1 
ATOM   7441 C  CZ  . PHE B 1 432 ? 23.325  -0.456  1.407   1   27.863 ? 424  PHE B CZ  1 
ATOM   7442 N  N   . GLN B 1 433 ? 20.402  5.512   4.704   1   25.93  ? 425  GLN B N   1 
ATOM   7443 C  CA  . GLN B 1 433 ? 19.926  6.261   5.864   1   25.498 ? 425  GLN B CA  1 
ATOM   7444 C  C   . GLN B 1 433 ? 19.021  7.423   5.464   1   27.673 ? 425  GLN B C   1 
ATOM   7445 O  O   . GLN B 1 433 ? 18.451  8.05    6.349   1   26.872 ? 425  GLN B O   1 
ATOM   7446 C  CB  . GLN B 1 433 ? 21.096  6.754   6.711   1   26.511 ? 425  GLN B CB  1 
ATOM   7447 C  CG  . GLN B 1 433 ? 22.017  5.611   7.152   1   26.248 ? 425  GLN B CG  1 
ATOM   7448 C  CD  . GLN B 1 433 ? 22.984  6.038   8.223   1   32.261 ? 425  GLN B CD  1 
ATOM   7449 O  OE1 . GLN B 1 433 ? 23.223  7.231   8.412   1   34.937 ? 425  GLN B OE1 1 
ATOM   7450 N  NE2 . GLN B 1 433 ? 23.603  5.074   8.886   1   35.359 ? 425  GLN B NE2 1 
ATOM   7451 N  N   . GLY B 1 434 ? 18.83   7.674   4.159   1   24.362 ? 426  GLY B N   1 
ATOM   7452 C  CA  . GLY B 1 434 ? 18.024  8.819   3.757   1   27.5   ? 426  GLY B CA  1 
ATOM   7453 C  C   . GLY B 1 434 ? 16.881  8.448   2.802   1   25.779 ? 426  GLY B C   1 
ATOM   7454 O  O   . GLY B 1 434 ? 16.387  9.306   2.059   1   26.156 ? 426  GLY B O   1 
ATOM   7455 N  N   . LEU B 1 435 ? 16.524  7.157   2.754   1   25.649 ? 427  LEU B N   1 
ATOM   7456 C  CA  . LEU B 1 435 ? 15.562  6.636   1.788   1   23.147 ? 427  LEU B CA  1 
ATOM   7457 C  C   . LEU B 1 435 ? 14.149  6.99    2.237   1   24.051 ? 427  LEU B C   1 
ATOM   7458 O  O   . LEU B 1 435 ? 13.593  6.389   3.174   1   23.626 ? 427  LEU B O   1 
ATOM   7459 C  CB  . LEU B 1 435 ? 15.743  5.128   1.58    1   21.467 ? 427  LEU B CB  1 
ATOM   7460 C  CG  . LEU B 1 435 ? 17.116  4.685   1.041   1   22.192 ? 427  LEU B CG  1 
ATOM   7461 C  CD1 . LEU B 1 435 ? 17.421  3.236   1.444   1   20.695 ? 427  LEU B CD1 1 
ATOM   7462 C  CD2 . LEU B 1 435 ? 17.218  4.811   -0.499  1   23.481 ? 427  LEU B CD2 1 
ATOM   7463 N  N   . ASN B 1 436 ? 13.556  7.979   1.551   1   26.801 ? 428  ASN B N   1 
ATOM   7464 C  CA  . ASN B 1 436 ? 12.285  8.536   1.992   1   24.88  ? 428  ASN B CA  1 
ATOM   7465 C  C   . ASN B 1 436 ? 11.244  8.484   0.873   1   25.186 ? 428  ASN B C   1 
ATOM   7466 O  O   . ASN B 1 436 ? 10.221  9.161   0.956   1   25.373 ? 428  ASN B O   1 
ATOM   7467 C  CB  . ASN B 1 436 ? 12.467  9.934   2.595   1   27.75  ? 428  ASN B CB  1 
ATOM   7468 C  CG  . ASN B 1 436 ? 12.903  10.98   1.585   1   27.983 ? 428  ASN B CG  1 
ATOM   7469 O  OD1 . ASN B 1 436 ? 13.325  10.67   0.46    1   26.164 ? 428  ASN B OD1 1 
ATOM   7470 N  ND2 . ASN B 1 436 ? 12.806  12.248  1.978   1   30.433 ? 428  ASN B ND2 1 
ATOM   7471 N  N   . GLY B 1 437 ? 11.515  7.704   -0.176  1   23.049 ? 429  GLY B N   1 
ATOM   7472 C  CA  . GLY B 1 437 ? 10.508  7.552   -1.209  1   24.149 ? 429  GLY B CA  1 
ATOM   7473 C  C   . GLY B 1 437 ? 10.612  6.235   -1.965  1   23.723 ? 429  GLY B C   1 
ATOM   7474 O  O   . GLY B 1 437 ? 11.528  5.444   -1.72   1   24.749 ? 429  GLY B O   1 
ATOM   7475 N  N   . LEU B 1 438 ? 9.659   6.035   -2.875  1   20.94  ? 430  LEU B N   1 
ATOM   7476 C  CA  . LEU B 1 438 ? 9.697   4.921   -3.817  1   21.301 ? 430  LEU B CA  1 
ATOM   7477 C  C   . LEU B 1 438 ? 9.612   5.489   -5.229  1   24.245 ? 430  LEU B C   1 
ATOM   7478 O  O   . LEU B 1 438 ? 8.939   6.497   -5.444  1   26.029 ? 430  LEU B O   1 
ATOM   7479 C  CB  . LEU B 1 438 ? 8.543   3.941   -3.609  1   21.135 ? 430  LEU B CB  1 
ATOM   7480 C  CG  . LEU B 1 438 ? 8.415   3.384   -2.188  1   21.135 ? 430  LEU B CG  1 
ATOM   7481 C  CD1 . LEU B 1 438 ? 7.12    2.575   -2.156  1   23.767 ? 430  LEU B CD1 1 
ATOM   7482 C  CD2 . LEU B 1 438 ? 9.616   2.48    -1.856  1   22.669 ? 430  LEU B CD2 1 
ATOM   7483 N  N   . ALA B 1 439 ? 10.272  4.808   -6.159  1   23.384 ? 431  ALA B N   1 
ATOM   7484 C  CA  . ALA B 1 439 ? 10.088  5.076   -7.588  1   24.458 ? 431  ALA B CA  1 
ATOM   7485 C  C   . ALA B 1 439 ? 9.532   3.851   -8.293  1   22.844 ? 431  ALA B C   1 
ATOM   7486 O  O   . ALA B 1 439 ? 9.97    2.716   -8.066  1   23.754 ? 431  ALA B O   1 
ATOM   7487 C  CB  . ALA B 1 439 ? 11.402  5.527   -8.173  1   21.33  ? 431  ALA B CB  1 
ATOM   7488 N  N   . HIS B 1 440 ? 8.586   4.075   -9.225  1   23.005 ? 432  HIS B N   1 
ATOM   7489 C  CA  . HIS B 1 440 ? 8.23    3.049   -10.171 1   22.225 ? 432  HIS B CA  1 
ATOM   7490 C  C   . HIS B 1 440 ? 8.754   3.441   -11.551 1   28.059 ? 432  HIS B C   1 
ATOM   7491 O  O   . HIS B 1 440 ? 8.195   4.335   -12.187 1   27.278 ? 432  HIS B O   1 
ATOM   7492 C  CB  . HIS B 1 440 ? 6.725   2.762   -10.206 1   24.489 ? 432  HIS B CB  1 
ATOM   7493 C  CG  . HIS B 1 440 ? 6.33    1.648   -11.127 1   25.357 ? 432  HIS B CG  1 
ATOM   7494 N  ND1 . HIS B 1 440 ? 5       1.377   -11.389 1   27.925 ? 432  HIS B ND1 1 
ATOM   7495 C  CD2 . HIS B 1 440 ? 7.026   0.702   -11.788 1   27.745 ? 432  HIS B CD2 1 
ATOM   7496 C  CE1 . HIS B 1 440 ? 4.908   0.33    -12.189 1   30.157 ? 432  HIS B CE1 1 
ATOM   7497 N  NE2 . HIS B 1 440 ? 6.141   -0.092  -12.457 1   27.91  ? 432  HIS B NE2 1 
ATOM   7498 N  N   . TYR B 1 441 ? 9.839   2.765   -11.961 1   24.635 ? 433  TYR B N   1 
ATOM   7499 C  CA  . TYR B 1 441 ? 10.491  2.981   -13.241 1   26.253 ? 433  TYR B CA  1 
ATOM   7500 C  C   . TYR B 1 441 ? 10.018  1.919   -14.219 1   25.696 ? 433  TYR B C   1 
ATOM   7501 O  O   . TYR B 1 441 ? 9.922   0.735   -13.878 1   26.503 ? 433  TYR B O   1 
ATOM   7502 C  CB  . TYR B 1 441 ? 12.016  2.933   -13.034 1   25.491 ? 433  TYR B CB  1 
ATOM   7503 C  CG  . TYR B 1 441 ? 12.763  2.884   -14.37  1   27.996 ? 433  TYR B CG  1 
ATOM   7504 C  CD1 . TYR B 1 441 ? 12.806  4.016   -15.19  1   28.102 ? 433  TYR B CD1 1 
ATOM   7505 C  CD2 . TYR B 1 441 ? 13.383  1.709   -14.812 1   25.605 ? 433  TYR B CD2 1 
ATOM   7506 C  CE1 . TYR B 1 441 ? 13.454  3.978   -16.419 1   29.853 ? 433  TYR B CE1 1 
ATOM   7507 C  CE2 . TYR B 1 441 ? 14.036  1.661   -16.039 1   26.733 ? 433  TYR B CE2 1 
ATOM   7508 C  CZ  . TYR B 1 441 ? 14.066  2.8     -16.837 1   30.547 ? 433  TYR B CZ  1 
ATOM   7509 O  OH  . TYR B 1 441 ? 14.736  2.776   -18.037 1   29.46  ? 433  TYR B OH  1 
ATOM   7510 N  N   . LYS B 1 442 ? 9.676   2.359   -15.449 1   26.044 ? 434  LYS B N   1 
ATOM   7511 C  CA  . LYS B 1 442 ? 9.267   1.436   -16.491 1   25.929 ? 434  LYS B CA  1 
ATOM   7512 C  C   . LYS B 1 442 ? 10.167  1.701   -17.695 1   29.427 ? 434  LYS B C   1 
ATOM   7513 O  O   . LYS B 1 442 ? 10.142  2.803   -18.245 1   28.49  ? 434  LYS B O   1 
ATOM   7514 C  CB  . LYS B 1 442 ? 7.826   1.801   -16.879 1   29.632 ? 434  LYS B CB  1 
ATOM   7515 C  CG  . LYS B 1 442 ? 6.766   1.309   -15.895 1   31.221 ? 434  LYS B CG  1 
ATOM   7516 C  CD  . LYS B 1 442 ? 5.376   1.753   -16.322 1   33.142 ? 434  LYS B CD  1 
ATOM   7517 C  CE  . LYS B 1 442 ? 4.345   1.036   -15.524 1   40.498 ? 434  LYS B CE  1 
ATOM   7518 N  NZ  . LYS B 1 442 ? 3.046   1.533   -15.999 1   44.968 ? 434  LYS B NZ  1 
ATOM   7519 N  N   . ARG B 1 443 ? 11.024  0.737   -18.012 1   26.138 ? 435  ARG B N   1 
ATOM   7520 C  CA  . ARG B 1 443 ? 12.014  0.919   -19.062 1   28.634 ? 435  ARG B CA  1 
ATOM   7521 C  C   . ARG B 1 443 ? 11.328  1.09    -20.428 1   29.895 ? 435  ARG B C   1 
ATOM   7522 O  O   . ARG B 1 443 ? 11.743  1.963   -21.181 1   30.989 ? 435  ARG B O   1 
ATOM   7523 C  CB  . ARG B 1 443 ? 12.961  -0.281  -19.11  1   25.525 ? 435  ARG B CB  1 
ATOM   7524 C  CG  . ARG B 1 443 ? 14.008  -0.175  -20.21  1   26.131 ? 435  ARG B CG  1 
ATOM   7525 C  CD  . ARG B 1 443 ? 14.927  -1.408  -20.211 1   23.825 ? 435  ARG B CD  1 
ATOM   7526 N  NE  . ARG B 1 443 ? 14.296  -2.728  -20.3   1   25.804 ? 435  ARG B NE  1 
ATOM   7527 C  CZ  . ARG B 1 443 ? 13.646  -3.215  -21.353 1   30.889 ? 435  ARG B CZ  1 
ATOM   7528 N  NH1 . ARG B 1 443 ? 13.752  -2.627  -22.553 1   30.134 ? 435  ARG B NH1 1 
ATOM   7529 N  NH2 . ARG B 1 443 ? 12.941  -4.332  -21.223 1   27.335 ? 435  ARG B NH2 1 
ATOM   7530 N  N   . LYS B 1 444 ? 10.288  0.288   -20.7   1   29.744 ? 436  LYS B N   1 
ATOM   7531 C  CA  . LYS B 1 444 ? 9.63    0.266   -22.011 1   35.411 ? 436  LYS B CA  1 
ATOM   7532 C  C   . LYS B 1 444 ? 8.974   1.62    -22.323 1   40.316 ? 436  LYS B C   1 
ATOM   7533 O  O   . LYS B 1 444 ? 9.096   2.095   -23.445 1   38.712 ? 436  LYS B O   1 
ATOM   7534 C  CB  . LYS B 1 444 ? 8.711   -0.95   -22.16  1   35.203 ? 436  LYS B CB  1 
ATOM   7535 C  CG  . LYS B 1 444 ? 9.45    -2.258  -22.426 1   37.314 ? 436  LYS B CG  1 
ATOM   7536 C  CD  . LYS B 1 444 ? 8.585   -3.505  -22.287 1   36.738 ? 436  LYS B CD  1 
ATOM   7537 C  CE  . LYS B 1 444 ? 9.302   -4.731  -22.737 1   34.539 ? 436  LYS B CE  1 
ATOM   7538 N  NZ  . LYS B 1 444 ? 8.586   -5.998  -22.561 1   41.126 ? 436  LYS B NZ  1 
ATOM   7539 N  N   . GLU B 1 445 ? 8.349   2.268   -21.325 1   34.759 ? 437  GLU B N   1 
ATOM   7540 C  CA  . GLU B 1 445 ? 7.745   3.601   -21.454 1   33.136 ? 437  GLU B CA  1 
ATOM   7541 C  C   . GLU B 1 445 ? 8.764   4.716   -21.191 1   37.606 ? 437  GLU B C   1 
ATOM   7542 O  O   . GLU B 1 445 ? 8.552   5.87    -21.563 1   41.52  ? 437  GLU B O   1 
ATOM   7543 C  CB  . GLU B 1 445 ? 6.521   3.79    -20.545 1   39.696 ? 437  GLU B CB  1 
ATOM   7544 C  CG  . GLU B 1 445 ? 5.329   2.893   -20.889 1   43.824 ? 437  GLU B CG  1 
ATOM   7545 C  CD  . GLU B 1 445 ? 5.371   1.431   -20.453 1   48.206 ? 437  GLU B CD  1 
ATOM   7546 O  OE1 . GLU B 1 445 ? 6.369   0.933   -19.856 1   44.672 ? 437  GLU B OE1 1 
ATOM   7547 O  OE2 . GLU B 1 445 ? 4.343   0.765   -20.677 1   50.172 ? 437  GLU B OE2 1 
ATOM   7548 N  N   . GLY B 1 446 ? 9.881   4.395   -20.534 1   32.748 ? 438  GLY B N   1 
ATOM   7549 C  CA  . GLY B 1 446 ? 10.88   5.38    -20.14  1   34.269 ? 438  GLY B CA  1 
ATOM   7550 C  C   . GLY B 1 446 ? 10.37   6.353   -19.07  1   38.886 ? 438  GLY B C   1 
ATOM   7551 O  O   . GLY B 1 446 ? 10.902  7.454   -18.949 1   40.362 ? 438  GLY B O   1 
ATOM   7552 N  N   . THR B 1 447 ? 9.356   5.933   -18.287 1   38.889 ? 439  THR B N   1 
ATOM   7553 C  CA  . THR B 1 447 ? 8.722   6.796   -17.291 1   35.958 ? 439  THR B CA  1 
ATOM   7554 C  C   . THR B 1 447 ? 9.14    6.393   -15.874 1   32.194 ? 439  THR B C   1 
ATOM   7555 O  O   . THR B 1 447 ? 9.429   5.222   -15.626 1   29.19  ? 439  THR B O   1 
ATOM   7556 C  CB  . THR B 1 447 ? 7.203   6.716   -17.413 1   34.893 ? 439  THR B CB  1 
ATOM   7557 O  OG1 . THR B 1 447 ? 6.814   5.346   -17.243 1   33.064 ? 439  THR B OG1 1 
ATOM   7558 C  CG2 . THR B 1 447 ? 6.666   7.354   -18.688 1   36.844 ? 439  THR B CG2 1 
ATOM   7559 N  N   . THR B 1 448 ? 9.145   7.38    -14.973 1   28.021 ? 440  THR B N   1 
ATOM   7560 C  CA  . THR B 1 448 ? 9.304   7.143   -13.537 1   28.405 ? 440  THR B CA  1 
ATOM   7561 C  C   . THR B 1 448 ? 8.209   7.908   -12.793 1   33.466 ? 440  THR B C   1 
ATOM   7562 O  O   . THR B 1 448 ? 8.011   9.116   -13.021 1   32.968 ? 440  THR B O   1 
ATOM   7563 C  CB  . THR B 1 448 ? 10.692  7.568   -13.039 1   32.603 ? 440  THR B CB  1 
ATOM   7564 O  OG1 . THR B 1 448 ? 11.633  6.976   -13.922 1   33.626 ? 440  THR B OG1 1 
ATOM   7565 C  CG2 . THR B 1 448 ? 10.987  7.067   -11.627 1   28.696 ? 440  THR B CG2 1 
ATOM   7566 N  N   . GLU B 1 449 ? 7.529   7.19    -11.879 1   29.153 ? 441  GLU B N   1 
ATOM   7567 C  CA  . GLU B 1 449 ? 6.565   7.792   -10.971 1   27.863 ? 441  GLU B CA  1 
ATOM   7568 C  C   . GLU B 1 449 ? 7.107   7.681   -9.554  1   29.249 ? 441  GLU B C   1 
ATOM   7569 O  O   . GLU B 1 449 ? 7.92    6.794   -9.284  1   27.088 ? 441  GLU B O   1 
ATOM   7570 C  CB  . GLU B 1 449 ? 5.23    7.093   -11.155 1   30.289 ? 441  GLU B CB  1 
ATOM   7571 C  CG  . GLU B 1 449 ? 4.659   7.356   -12.545 1   36.182 ? 441  GLU B CG  1 
ATOM   7572 C  CD  . GLU B 1 449 ? 3.596   6.32    -12.827 1   44.076 ? 441  GLU B CD  1 
ATOM   7573 O  OE1 . GLU B 1 449 ? 2.461   6.601   -12.388 1   51.018 ? 441  GLU B OE1 1 
ATOM   7574 O  OE2 . GLU B 1 449 ? 3.898   5.236   -13.396 1   47.338 ? 441  GLU B OE2 1 
ATOM   7575 N  N   . TRP B 1 450 ? 6.682   8.609   -8.686  1   27.078 ? 442  TRP B N   1 
ATOM   7576 C  CA  . TRP B 1 450 ? 7.351   8.783   -7.401  1   26.777 ? 442  TRP B CA  1 
ATOM   7577 C  C   . TRP B 1 450 ? 6.321   8.759   -6.268  1   30.725 ? 442  TRP B C   1 
ATOM   7578 O  O   . TRP B 1 450 ? 5.251   9.364   -6.383  1   27.514 ? 442  TRP B O   1 
ATOM   7579 C  CB  . TRP B 1 450 ? 8.124   10.107  -7.403  1   29.592 ? 442  TRP B CB  1 
ATOM   7580 C  CG  . TRP B 1 450 ? 9.133   10.228  -8.52   1   30.147 ? 442  TRP B CG  1 
ATOM   7581 C  CD1 . TRP B 1 450 ? 8.894   10.623  -9.805  1   34.676 ? 442  TRP B CD1 1 
ATOM   7582 C  CD2 . TRP B 1 450 ? 10.547  9.928   -8.445  1   30.477 ? 442  TRP B CD2 1 
ATOM   7583 N  NE1 . TRP B 1 450 ? 10.057  10.598  -10.533 1   34.333 ? 442  TRP B NE1 1 
ATOM   7584 C  CE2 . TRP B 1 450 ? 11.089  10.17   -9.739  1   30.226 ? 442  TRP B CE2 1 
ATOM   7585 C  CE3 . TRP B 1 450 ? 11.41   9.486   -7.428  1   28.53  ? 442  TRP B CE3 1 
ATOM   7586 C  CZ2 . TRP B 1 450 ? 12.439  9.978   -10.04  1   30.6   ? 442  TRP B CZ2 1 
ATOM   7587 C  CZ3 . TRP B 1 450 ? 12.739  9.259   -7.738  1   29.048 ? 442  TRP B CZ3 1 
ATOM   7588 C  CH2 . TRP B 1 450 ? 13.257  9.514   -9.028  1   29.387 ? 442  TRP B CH2 1 
ATOM   7589 N  N   . TYR B 1 451 ? 6.674   8.077   -5.176  1   26.315 ? 443  TYR B N   1 
ATOM   7590 C  CA  . TYR B 1 451 ? 5.903   8.077   -3.941  1   26.222 ? 443  TYR B CA  1 
ATOM   7591 C  C   . TYR B 1 451 ? 6.777   8.692   -2.853  1   27.314 ? 443  TYR B C   1 
ATOM   7592 O  O   . TYR B 1 451 ? 7.9     8.231   -2.633  1   26.817 ? 443  TYR B O   1 
ATOM   7593 C  CB  . TYR B 1 451 ? 5.421   6.657   -3.578  1   28.361 ? 443  TYR B CB  1 
ATOM   7594 C  CG  . TYR B 1 451 ? 4.652   6.701   -2.263  1   25.7   ? 443  TYR B CG  1 
ATOM   7595 C  CD1 . TYR B 1 451 ? 3.306   7.1     -2.225  1   25.505 ? 443  TYR B CD1 1 
ATOM   7596 C  CD2 . TYR B 1 451 ? 5.275   6.358   -1.056  1   24.17  ? 443  TYR B CD2 1 
ATOM   7597 C  CE1 . TYR B 1 451 ? 2.61    7.177   -1.022  1   23.864 ? 443  TYR B CE1 1 
ATOM   7598 C  CE2 . TYR B 1 451 ? 4.589   6.46    0.151   1   26.393 ? 443  TYR B CE2 1 
ATOM   7599 C  CZ  . TYR B 1 451 ? 3.264   6.895   0.167   1   26.782 ? 443  TYR B CZ  1 
ATOM   7600 O  OH  . TYR B 1 451 ? 2.601   7.036   1.365   1   24.702 ? 443  TYR B OH  1 
ATOM   7601 N  N   . TYR B 1 452 ? 6.224   9.699   -2.141  1   27.296 ? 444  TYR B N   1 
ATOM   7602 C  CA  . TYR B 1 452 ? 6.941   10.338  -1.054  1   24.101 ? 444  TYR B CA  1 
ATOM   7603 C  C   . TYR B 1 452 ? 6.402   9.767   0.257   1   24.241 ? 444  TYR B C   1 
ATOM   7604 O  O   . TYR B 1 452 ? 5.179   9.76    0.445   1   27.941 ? 444  TYR B O   1 
ATOM   7605 C  CB  . TYR B 1 452 ? 6.733   11.863  -1.093  1   25.695 ? 444  TYR B CB  1 
ATOM   7606 C  CG  . TYR B 1 452 ? 7.379   12.63   0.056   1   26.863 ? 444  TYR B CG  1 
ATOM   7607 C  CD1 . TYR B 1 452 ? 8.738   12.503  0.363   1   26.758 ? 444  TYR B CD1 1 
ATOM   7608 C  CD2 . TYR B 1 452 ? 6.617   13.473  0.849   1   29.054 ? 444  TYR B CD2 1 
ATOM   7609 C  CE1 . TYR B 1 452 ? 9.316   13.226  1.399   1   30.164 ? 444  TYR B CE1 1 
ATOM   7610 C  CE2 . TYR B 1 452 ? 7.183   14.192  1.889   1   29.53  ? 444  TYR B CE2 1 
ATOM   7611 C  CZ  . TYR B 1 452 ? 8.528   14.076  2.159   1   30.214 ? 444  TYR B CZ  1 
ATOM   7612 O  OH  . TYR B 1 452 ? 9.057   14.806  3.167   1   29.592 ? 444  TYR B OH  1 
ATOM   7613 N  N   . ALA B 1 453 ? 7.316   9.298   1.132   1   25.646 ? 445  ALA B N   1 
ATOM   7614 C  CA  . ALA B 1 453 ? 6.929   8.654   2.39    1   26.373 ? 445  ALA B CA  1 
ATOM   7615 C  C   . ALA B 1 453 ? 6.253   9.623   3.351   1   26.23  ? 445  ALA B C   1 
ATOM   7616 O  O   . ALA B 1 453 ? 5.428   9.176   4.133   1   27.481 ? 445  ALA B O   1 
ATOM   7617 C  CB  . ALA B 1 453 ? 8.106   7.997   3.082   1   24.875 ? 445  ALA B CB  1 
ATOM   7618 N  N   . GLY B 1 454 ? 6.591   10.918  3.274   1   28.375 ? 446  GLY B N   1 
ATOM   7619 C  CA  . GLY B 1 454 ? 6.033   11.916  4.184   1   28.308 ? 446  GLY B CA  1 
ATOM   7620 C  C   . GLY B 1 454 ? 7.146   12.59   4.955   1   25.459 ? 446  GLY B C   1 
ATOM   7621 O  O   . GLY B 1 454 ? 8.275   12.074  5.03    1   27.477 ? 446  GLY B O   1 
ATOM   7622 N  N   . ASP B 1 455 ? 6.861   13.802  5.482   1   27.072 ? 447  ASP B N   1 
ATOM   7623 C  CA  . ASP B 1 455 ? 7.83    14.501  6.32    1   33.118 ? 447  ASP B CA  1 
ATOM   7624 C  C   . ASP B 1 455 ? 8.029   13.684  7.587   1   28.09  ? 447  ASP B C   1 
ATOM   7625 O  O   . ASP B 1 455 ? 7.073   13.094  8.07    1   34.306 ? 447  ASP B O   1 
ATOM   7626 C  CB  . ASP B 1 455 ? 7.373   15.907  6.716   1   33.557 ? 447  ASP B CB  1 
ATOM   7627 C  CG  . ASP B 1 455 ? 7.166   16.91   5.58    1   43.192 ? 447  ASP B CG  1 
ATOM   7628 O  OD1 . ASP B 1 455 ? 7.509   16.579  4.415   1   33.945 ? 447  ASP B OD1 1 
ATOM   7629 O  OD2 . ASP B 1 455 ? 6.649   18.022  5.86    1   39.413 ? 447  ASP B OD2 1 
ATOM   7630 N  N   . ASN B 1 456 ? 9.284   13.626  8.064   1   32.812 ? 448  ASN B N   1 
ATOM   7631 C  CA  . ASN B 1 456 ? 9.652   12.881  9.268   1   36.861 ? 448  ASN B CA  1 
ATOM   7632 C  C   . ASN B 1 456 ? 9.342   11.391  9.072   1   33.75  ? 448  ASN B C   1 
ATOM   7633 O  O   . ASN B 1 456 ? 8.91    10.724  10.005  1   34.244 ? 448  ASN B O   1 
ATOM   7634 C  CB  . ASN B 1 456 ? 9.003   13.467  10.528  1   40.282 ? 448  ASN B CB  1 
ATOM   7635 C  CG  . ASN B 1 456 ? 9.316   14.934  10.695  1   46.326 ? 448  ASN B CG  1 
ATOM   7636 O  OD1 . ASN B 1 456 ? 8.397   15.754  10.805  1   53.991 ? 448  ASN B OD1 1 
ATOM   7637 N  ND2 . ASN B 1 456 ? 10.596  15.28   10.7    1   46.552 ? 448  ASN B ND2 1 
ATOM   7638 N  N   . CYS B 1 457 ? 9.487   10.911  7.831   1   31.286 ? 449  CYS B N   1 
ATOM   7639 C  CA  . CYS B 1 457 ? 9.295   9.504   7.511   1   26.708 ? 449  CYS B CA  1 
ATOM   7640 C  C   . CYS B 1 457 ? 10.473  8.99    6.683   1   28.634 ? 449  CYS B C   1 
ATOM   7641 O  O   . CYS B 1 457 ? 11.098  9.715   5.882   1   25.724 ? 449  CYS B O   1 
ATOM   7642 C  CB  . CYS B 1 457 ? 8.019   9.275   6.699   1   28.417 ? 449  CYS B CB  1 
ATOM   7643 S  SG  . CYS B 1 457 ? 6.479   9.701   7.562   1   29.49  ? 449  CYS B SG  1 
ATOM   7644 N  N   . LEU B 1 458 ? 10.758  7.706   6.886   1   25.235 ? 450  LEU B N   1 
ATOM   7645 C  CA  . LEU B 1 458 ? 11.547  6.903   5.968   1   23.716 ? 450  LEU B CA  1 
ATOM   7646 C  C   . LEU B 1 458 ? 10.664  5.785   5.433   1   23.738 ? 450  LEU B C   1 
ATOM   7647 O  O   . LEU B 1 458 ? 9.621   5.473   6.017   1   26.535 ? 450  LEU B O   1 
ATOM   7648 C  CB  . LEU B 1 458 ? 12.821  6.349   6.634   1   23.159 ? 450  LEU B CB  1 
ATOM   7649 C  CG  . LEU B 1 458 ? 13.796  7.394   7.215   1   27.023 ? 450  LEU B CG  1 
ATOM   7650 C  CD1 . LEU B 1 458 ? 14.894  6.792   8.108   1   26.967 ? 450  LEU B CD1 1 
ATOM   7651 C  CD2 . LEU B 1 458 ? 14.439  8.215   6.068   1   31.983 ? 450  LEU B CD2 1 
ATOM   7652 N  N   . ILE B 1 459 ? 11.037  5.247   4.263   1   22.354 ? 451  ILE B N   1 
ATOM   7653 C  CA  . ILE B 1 459 ? 10.329  4.096   3.72    1   20.532 ? 451  ILE B CA  1 
ATOM   7654 C  C   . ILE B 1 459 ? 11.374  3.063   3.309   1   21.304 ? 451  ILE B C   1 
ATOM   7655 O  O   . ILE B 1 459 ? 12.464  3.422   2.883   1   23.429 ? 451  ILE B O   1 
ATOM   7656 C  CB  . ILE B 1 459 ? 9.368   4.491   2.572   1   21.072 ? 451  ILE B CB  1 
ATOM   7657 C  CG1 . ILE B 1 459 ? 8.4     3.38    2.174   1   20.74  ? 451  ILE B CG1 1 
ATOM   7658 C  CG2 . ILE B 1 459 ? 10.127  5.042   1.359   1   22.311 ? 451  ILE B CG2 1 
ATOM   7659 C  CD1 . ILE B 1 459 ? 7.189   3.893   1.392   1   21.166 ? 451  ILE B CD1 1 
ATOM   7660 N  N   . GLN B 1 460 ? 11.009  1.782   3.437   1   22.397 ? 452  GLN B N   1 
ATOM   7661 C  CA  . GLN B 1 460 ? 11.912  0.662   3.192   1   20.147 ? 452  GLN B CA  1 
ATOM   7662 C  C   . GLN B 1 460 ? 11.614  0.03    1.84    1   20.103 ? 452  GLN B C   1 
ATOM   7663 O  O   . GLN B 1 460 ? 10.807  0.547   1.05    1   20.037 ? 452  GLN B O   1 
ATOM   7664 C  CB  . GLN B 1 460 ? 11.827  -0.254  4.408   1   17.948 ? 452  GLN B CB  1 
ATOM   7665 C  CG  . GLN B 1 460 ? 12.404  0.401   5.662   1   21.372 ? 452  GLN B CG  1 
ATOM   7666 C  CD  . GLN B 1 460 ? 11.948  -0.33   6.91    1   24.74  ? 452  GLN B CD  1 
ATOM   7667 O  OE1 . GLN B 1 460 ? 12.039  -1.566  7.031   1   23.738 ? 452  GLN B OE1 1 
ATOM   7668 N  NE2 . GLN B 1 460 ? 11.462  0.442   7.865   1   21.827 ? 452  GLN B NE2 1 
ATOM   7669 N  N   . GLU B 1 461 ? 12.259  -1.117  1.584   1   20.066 ? 453  GLU B N   1 
ATOM   7670 C  CA  . GLU B 1 461 ? 12.239  -1.735  0.263   1   19.669 ? 453  GLU B CA  1 
ATOM   7671 C  C   . GLU B 1 461 ? 10.807  -2.068  -0.153  1   18.544 ? 453  GLU B C   1 
ATOM   7672 O  O   . GLU B 1 461 ? 10.032  -2.653  0.625   1   18.467 ? 453  GLU B O   1 
ATOM   7673 C  CB  . GLU B 1 461 ? 13.089  -3.012  0.302   1   19.164 ? 453  GLU B CB  1 
ATOM   7674 C  CG  . GLU B 1 461 ? 12.99   -3.806  -1.013  1   19.096 ? 453  GLU B CG  1 
ATOM   7675 C  CD  . GLU B 1 461 ? 13.596  -5.17   -0.779  1   22.159 ? 453  GLU B CD  1 
ATOM   7676 O  OE1 . GLU B 1 461 ? 13.087  -5.808  0.178   1   21.581 ? 453  GLU B OE1 1 
ATOM   7677 O  OE2 . GLU B 1 461 ? 14.503  -5.585  -1.517  1   23.658 ? 453  GLU B OE2 1 
ATOM   7678 N  N   . PRO B 1 462 ? 10.42   -1.751  -1.401  1   19.426 ? 454  PRO B N   1 
ATOM   7679 C  CA  . PRO B 1 462 ? 9.085   -2.1    -1.877  1   19.692 ? 454  PRO B CA  1 
ATOM   7680 C  C   . PRO B 1 462 ? 9.019   -3.531  -2.386  1   19.761 ? 454  PRO B C   1 
ATOM   7681 O  O   . PRO B 1 462 ? 10.028  -4.055  -2.897  1   20.767 ? 454  PRO B O   1 
ATOM   7682 C  CB  . PRO B 1 462 ? 8.901   -1.159  -3.09   1   20.784 ? 454  PRO B CB  1 
ATOM   7683 C  CG  . PRO B 1 462 ? 10.315  -0.934  -3.608  1   21.246 ? 454  PRO B CG  1 
ATOM   7684 C  CD  . PRO B 1 462 ? 11.211  -0.959  -2.389  1   20.988 ? 454  PRO B CD  1 
ATOM   7685 N  N   . VAL B 1 463 ? 7.806   -4.106  -2.319  1   19.248 ? 455  VAL B N   1 
ATOM   7686 C  CA  . VAL B 1 463 ? 7.514   -5.384  -2.956  1   21.047 ? 455  VAL B CA  1 
ATOM   7687 C  C   . VAL B 1 463 ? 6.246   -5.198  -3.795  1   22.298 ? 455  VAL B C   1 
ATOM   7688 O  O   . VAL B 1 463 ? 5.414   -4.358  -3.46   1   23.96  ? 455  VAL B O   1 
ATOM   7689 C  CB  . VAL B 1 463 ? 7.33    -6.541  -1.96   1   19.941 ? 455  VAL B CB  1 
ATOM   7690 C  CG1 . VAL B 1 463 ? 8.615   -6.777  -1.152  1   19.008 ? 455  VAL B CG1 1 
ATOM   7691 C  CG2 . VAL B 1 463 ? 6.101   -6.338  -1.03   1   19.924 ? 455  VAL B CG2 1 
ATOM   7692 N  N   . PHE B 1 464 ? 6.118   -6.044  -4.825  1   22.127 ? 456  PHE B N   1 
ATOM   7693 C  CA  . PHE B 1 464 ? 5.018   -5.937  -5.781  1   23.899 ? 456  PHE B CA  1 
ATOM   7694 C  C   . PHE B 1 464 ? 4.162   -7.188  -5.78   1   20.634 ? 456  PHE B C   1 
ATOM   7695 O  O   . PHE B 1 464 ? 4.646   -8.312  -5.868  1   20.858 ? 456  PHE B O   1 
ATOM   7696 C  CB  . PHE B 1 464 ? 5.601   -5.634  -7.169  1   22.372 ? 456  PHE B CB  1 
ATOM   7697 C  CG  . PHE B 1 464 ? 4.548   -5.728  -8.262  1   26.405 ? 456  PHE B CG  1 
ATOM   7698 C  CD1 . PHE B 1 464 ? 3.663   -4.67   -8.483  1   26.711 ? 456  PHE B CD1 1 
ATOM   7699 C  CD2 . PHE B 1 464 ? 4.425   -6.891  -9.033  1   25.027 ? 456  PHE B CD2 1 
ATOM   7700 C  CE1 . PHE B 1 464 ? 2.713   -4.736  -9.504  1   24.948 ? 456  PHE B CE1 1 
ATOM   7701 C  CE2 . PHE B 1 464 ? 3.451   -6.963  -10.029 1   22.933 ? 456  PHE B CE2 1 
ATOM   7702 C  CZ  . PHE B 1 464 ? 2.606   -5.886  -10.258 1   24.436 ? 456  PHE B CZ  1 
ATOM   7703 N  N   . SER B 1 465 ? 2.843   -6.973  -5.803  1   21.98  ? 457  SER B N   1 
ATOM   7704 C  CA  . SER B 1 465 ? 1.88    -8.048  -5.952  1   22.137 ? 457  SER B CA  1 
ATOM   7705 C  C   . SER B 1 465 ? 1.054   -7.728  -7.196  1   26.385 ? 457  SER B C   1 
ATOM   7706 O  O   . SER B 1 465 ? 0.408   -6.676  -7.217  1   23.2   ? 457  SER B O   1 
ATOM   7707 C  CB  . SER B 1 465 ? 0.951   -8.138  -4.738  1   22.381 ? 457  SER B CB  1 
ATOM   7708 O  OG  . SER B 1 465 ? -0.101  -9.092  -4.947  1   23.306 ? 457  SER B OG  1 
ATOM   7709 N  N   . PRO B 1 466 ? 1.002   -8.627  -8.202  1   26.309 ? 458  PRO B N   1 
ATOM   7710 C  CA  . PRO B 1 466 ? 0.196   -8.354  -9.39   1   27.485 ? 458  PRO B CA  1 
ATOM   7711 C  C   . PRO B 1 466 ? -1.296  -8.275  -9.06   1   29.416 ? 458  PRO B C   1 
ATOM   7712 O  O   . PRO B 1 466 ? -1.771  -8.995  -8.183  1   29.131 ? 458  PRO B O   1 
ATOM   7713 C  CB  . PRO B 1 466 ? 0.497   -9.535  -10.333 1   26.348 ? 458  PRO B CB  1 
ATOM   7714 C  CG  . PRO B 1 466 ? 1.623   -10.297 -9.683  1   31.187 ? 458  PRO B CG  1 
ATOM   7715 C  CD  . PRO B 1 466 ? 1.669   -9.942  -8.224  1   26.058 ? 458  PRO B CD  1 
ATOM   7716 N  N   . ARG B 1 467 ? -2.036  -7.443  -9.79   1   28.09  ? 459  ARG B N   1 
ATOM   7717 C  CA  . ARG B 1 467 ? -3.465  -7.253  -9.551  1   30.139 ? 459  ARG B CA  1 
ATOM   7718 C  C   . ARG B 1 467 ? -4.219  -8.582  -9.651  1   32.488 ? 459  ARG B C   1 
ATOM   7719 O  O   . ARG B 1 467 ? -5.16   -8.813  -8.89   1   32.052 ? 459  ARG B O   1 
ATOM   7720 C  CB  . ARG B 1 467 ? -4.056  -6.208  -10.503 1   29.237 ? 459  ARG B CB  1 
ATOM   7721 C  CG  . ARG B 1 467 ? -5.425  -5.676  -10.078 1   30.235 ? 459  ARG B CG  1 
ATOM   7722 C  CD  . ARG B 1 467 ? -5.946  -4.626  -11.06  1   29.932 ? 459  ARG B CD  1 
ATOM   7723 N  NE  . ARG B 1 467 ? -5.022  -3.505  -11.253 1   30.193 ? 459  ARG B NE  1 
ATOM   7724 C  CZ  . ARG B 1 467 ? -4.738  -2.558  -10.36  1   29.541 ? 459  ARG B CZ  1 
ATOM   7725 N  NH1 . ARG B 1 467 ? -5.533  -2.348  -9.304  1   29.842 ? 459  ARG B NH1 1 
ATOM   7726 N  NH2 . ARG B 1 467 ? -3.693  -1.768  -10.54  1   34.053 ? 459  ARG B NH2 1 
ATOM   7727 N  N   . SER B 1 468 ? -3.795  -9.42   -10.604 1   30.622 ? 460  SER B N   1 
ATOM   7728 C  CA  . SER B 1 468 ? -4.247  -10.786 -10.825 1   32.512 ? 460  SER B CA  1 
ATOM   7729 C  C   . SER B 1 468 ? -3.131  -11.505 -11.574 1   31.01  ? 460  SER B C   1 
ATOM   7730 O  O   . SER B 1 468 ? -2.217  -10.85  -12.036 1   31.694 ? 460  SER B O   1 
ATOM   7731 C  CB  . SER B 1 468 ? -5.532  -10.809 -11.63  1   32.747 ? 460  SER B CB  1 
ATOM   7732 O  OG  . SER B 1 468 ? -5.251  -10.322 -12.933 1   34.408 ? 460  SER B OG  1 
ATOM   7733 N  N   . LYS B 1 469 ? -3.255  -12.835 -11.715 1   33.99  ? 461  LYS B N   1 
ATOM   7734 C  CA  . LYS B 1 469 ? -2.255  -13.716 -12.303 1   46.655 ? 461  LYS B CA  1 
ATOM   7735 C  C   . LYS B 1 469 ? -1.826  -13.242 -13.697 1   49.965 ? 461  LYS B C   1 
ATOM   7736 O  O   . LYS B 1 469 ? -0.623  -13.291 -14.012 1   42.707 ? 461  LYS B O   1 
ATOM   7737 C  CB  . LYS B 1 469 ? -2.749  -15.17  -12.229 1   53.67  ? 461  LYS B CB  1 
ATOM   7738 C  CG  . LYS B 1 469 ? -1.655  -16.223 -12.01  1   67.983 ? 461  LYS B CG  1 
ATOM   7739 C  CD  . LYS B 1 469 ? -0.959  -16.224 -10.645 1   80.497 ? 461  LYS B CD  1 
ATOM   7740 C  CE  . LYS B 1 469 ? 0.483   -16.674 -10.662 1   85.634 ? 461  LYS B CE  1 
ATOM   7741 N  NZ  . LYS B 1 469 ? 0.644   -18.114 -10.888 1   86.9   ? 461  LYS B NZ  1 
ATOM   7742 N  N   . ASP B 1 470 ? -2.796  -12.727 -14.476 1   40.343 ? 462  ASP B N   1 
ATOM   7743 C  CA  . ASP B 1 470 ? -2.59   -12.281 -15.852 1   42.78  ? 462  ASP B CA  1 
ATOM   7744 C  C   . ASP B 1 470 ? -2.651  -10.754 -15.989 1   42.028 ? 462  ASP B C   1 
ATOM   7745 O  O   . ASP B 1 470 ? -2.796  -10.244 -17.096 1   38.475 ? 462  ASP B O   1 
ATOM   7746 C  CB  . ASP B 1 470 ? -3.577  -12.938 -16.809 1   55.235 ? 462  ASP B CB  1 
ATOM   7747 C  CG  . ASP B 1 470 ? -3.506  -14.457 -16.915 1   74.876 ? 462  ASP B CG  1 
ATOM   7748 O  OD1 . ASP B 1 470 ? -2.384  -14.989 -17.094 1   77.955 ? 462  ASP B OD1 1 
ATOM   7749 O  OD2 . ASP B 1 470 ? -4.58   -15.102 -16.861 1   81.931 ? 462  ASP B OD2 1 
ATOM   7750 N  N   . ALA B 1 471 ? -2.508  -10.003 -14.886 1   34.243 ? 463  ALA B N   1 
ATOM   7751 C  CA  . ALA B 1 471 ? -2.376  -8.55   -14.974 1   29.176 ? 463  ALA B CA  1 
ATOM   7752 C  C   . ALA B 1 471 ? -1.149  -8.194  -15.811 1   32.387 ? 463  ALA B C   1 
ATOM   7753 O  O   . ALA B 1 471 ? -0.167  -8.929  -15.75  1   34.902 ? 463  ALA B O   1 
ATOM   7754 C  CB  . ALA B 1 471 ? -2.249  -7.941  -13.583 1   28.073 ? 463  ALA B CB  1 
ATOM   7755 N  N   . PRO B 1 472 ? -1.123  -7.072  -16.575 1   31.737 ? 464  PRO B N   1 
ATOM   7756 C  CA  . PRO B 1 472 ? 0.102   -6.645  -17.24  1   31.606 ? 464  PRO B CA  1 
ATOM   7757 C  C   . PRO B 1 472 ? 1.262   -6.462  -16.252 1   34.766 ? 464  PRO B C   1 
ATOM   7758 O  O   . PRO B 1 472 ? 1.045   -6.274  -15.044 1   29.822 ? 464  PRO B O   1 
ATOM   7759 C  CB  . PRO B 1 472 ? -0.236  -5.277  -17.817 1   31.143 ? 464  PRO B CB  1 
ATOM   7760 C  CG  . PRO B 1 472 ? -1.752  -5.415  -18.059 1   33.597 ? 464  PRO B CG  1 
ATOM   7761 C  CD  . PRO B 1 472 ? -2.248  -6.145  -16.839 1   31.011 ? 464  PRO B CD  1 
ATOM   7762 N  N   . GLU B 1 473 ? 2.492   -6.489  -16.774 1   32.505 ? 465  GLU B N   1 
ATOM   7763 C  CA  . GLU B 1 473 ? 3.671   -6.294  -15.934 1   29.337 ? 465  GLU B CA  1 
ATOM   7764 C  C   . GLU B 1 473 ? 3.573   -5.001  -15.129 1   29.764 ? 465  GLU B C   1 
ATOM   7765 O  O   . GLU B 1 473 ? 3.277   -3.923  -15.662 1   25.293 ? 465  GLU B O   1 
ATOM   7766 C  CB  . GLU B 1 473 ? 4.916   -6.178  -16.805 1   31.234 ? 465  GLU B CB  1 
ATOM   7767 C  CG  . GLU B 1 473 ? 6.203   -6.069  -15.975 1   28.832 ? 465  GLU B CG  1 
ATOM   7768 C  CD  . GLU B 1 473 ? 7.486   -6.028  -16.788 1   33.632 ? 465  GLU B CD  1 
ATOM   7769 O  OE1 . GLU B 1 473 ? 7.375   -6.193  -18.053 1   30.188 ? 465  GLU B OE1 1 
ATOM   7770 O  OE2 . GLU B 1 473 ? 8.564   -5.829  -16.147 1   28.713 ? 465  GLU B OE2 1 
ATOM   7771 N  N   . GLY B 1 474 ? 3.785   -5.121  -13.804 1   28.042 ? 466  GLY B N   1 
ATOM   7772 C  CA  . GLY B 1 474 ? 3.868   -3.918  -12.982 1   24.675 ? 466  GLY B CA  1 
ATOM   7773 C  C   . GLY B 1 474 ? 2.491   -3.313  -12.682 1   25.914 ? 466  GLY B C   1 
ATOM   7774 O  O   . GLY B 1 474 ? 2.416   -2.198  -12.169 1   26.029 ? 466  GLY B O   1 
ATOM   7775 N  N   . ASP B 1 475 ? 1.422   -4.043  -13.002 1   26.673 ? 467  ASP B N   1 
ATOM   7776 C  CA  . ASP B 1 475 ? 0.065   -3.608  -12.695 1   27.674 ? 467  ASP B CA  1 
ATOM   7777 C  C   . ASP B 1 475 ? -0.426  -4.346  -11.442 1   24.436 ? 467  ASP B C   1 
ATOM   7778 O  O   . ASP B 1 475 ? -0.626  -5.557  -11.448 1   28.032 ? 467  ASP B O   1 
ATOM   7779 C  CB  . ASP B 1 475 ? -0.894  -3.841  -13.845 1   25.373 ? 467  ASP B CB  1 
ATOM   7780 C  CG  . ASP B 1 475 ? -2.323  -3.429  -13.511 1   29.355 ? 467  ASP B CG  1 
ATOM   7781 O  OD1 . ASP B 1 475 ? -2.533  -2.242  -13.202 1   30.144 ? 467  ASP B OD1 1 
ATOM   7782 O  OD2 . ASP B 1 475 ? -3.194  -4.302  -13.541 1   36.537 ? 467  ASP B OD2 1 
ATOM   7783 N  N   . GLY B 1 476 ? -0.622  -3.585  -10.372 1   27.785 ? 468  GLY B N   1 
ATOM   7784 C  CA  . GLY B 1 476 ? -0.946  -4.224  -9.106  1   28.177 ? 468  GLY B CA  1 
ATOM   7785 C  C   . GLY B 1 476 ? -0.652  -3.303  -7.94   1   25.327 ? 468  GLY B C   1 
ATOM   7786 O  O   . GLY B 1 476 ? -0.873  -2.097  -8.004  1   25.677 ? 468  GLY B O   1 
ATOM   7787 N  N   . PHE B 1 477 ? -0.128  -3.921  -6.885  1   24.541 ? 469  PHE B N   1 
ATOM   7788 C  CA  . PHE B 1 477 ? 0.018   -3.222  -5.62   1   23.867 ? 469  PHE B CA  1 
ATOM   7789 C  C   . PHE B 1 477 ? 1.481   -3.268  -5.184  1   21.276 ? 469  PHE B C   1 
ATOM   7790 O  O   . PHE B 1 477 ? 2.111   -4.337  -5.282  1   22.809 ? 469  PHE B O   1 
ATOM   7791 C  CB  . PHE B 1 477 ? -0.932  -3.733  -4.532  1   23.201 ? 469  PHE B CB  1 
ATOM   7792 C  CG  . PHE B 1 477 ? -2.38   -3.663  -5.011  1   25.128 ? 469  PHE B CG  1 
ATOM   7793 C  CD1 . PHE B 1 477 ? -3.077  -2.452  -4.959  1   29.147 ? 469  PHE B CD1 1 
ATOM   7794 C  CD2 . PHE B 1 477 ? -2.994  -4.793  -5.577  1   26.624 ? 469  PHE B CD2 1 
ATOM   7795 C  CE1 . PHE B 1 477 ? -4.372  -2.358  -5.491  1   29.238 ? 469  PHE B CE1 1 
ATOM   7796 C  CE2 . PHE B 1 477 ? -4.292  -4.69   -6.109  1   30.306 ? 469  PHE B CE2 1 
ATOM   7797 C  CZ  . PHE B 1 477 ? -4.968  -3.469  -6.05   1   27.096 ? 469  PHE B CZ  1 
ATOM   7798 N  N   . VAL B 1 478 ? 1.93    -2.118  -4.673  1   20.293 ? 470  VAL B N   1 
ATOM   7799 C  CA  . VAL B 1 478 ? 3.259   -2.007  -4.078  1   22.667 ? 470  VAL B CA  1 
ATOM   7800 C  C   . VAL B 1 478 ? 3.085   -1.812  -2.57   1   22.681 ? 470  VAL B C   1 
ATOM   7801 O  O   . VAL B 1 478 ? 2.258   -1.005  -2.139  1   23.747 ? 470  VAL B O   1 
ATOM   7802 C  CB  . VAL B 1 478 ? 4.086   -0.893  -4.733  1   22.618 ? 470  VAL B CB  1 
ATOM   7803 C  CG1 . VAL B 1 478 ? 5.397   -0.582  -3.977  1   22.802 ? 470  VAL B CG1 1 
ATOM   7804 C  CG2 . VAL B 1 478 ? 4.42    -1.31   -6.159  1   23.618 ? 470  VAL B CG2 1 
ATOM   7805 N  N   . LEU B 1 479 ? 3.858   -2.573  -1.792  1   20.562 ? 471  LEU B N   1 
ATOM   7806 C  CA  . LEU B 1 479 ? 3.785   -2.5    -0.332  1   19.05  ? 471  LEU B CA  1 
ATOM   7807 C  C   . LEU B 1 479 ? 5.185   -2.174  0.173   1   21.548 ? 471  LEU B C   1 
ATOM   7808 O  O   . LEU B 1 479 ? 6.157   -2.654  -0.412  1   22.041 ? 471  LEU B O   1 
ATOM   7809 C  CB  . LEU B 1 479 ? 3.366   -3.848  0.235   1   20.637 ? 471  LEU B CB  1 
ATOM   7810 C  CG  . LEU B 1 479 ? 1.9     -4.275  0.028   1   26.671 ? 471  LEU B CG  1 
ATOM   7811 C  CD1 . LEU B 1 479 ? 1.659   -4.726  -1.394  1   30.531 ? 471  LEU B CD1 1 
ATOM   7812 C  CD2 . LEU B 1 479 ? 1.73    -5.453  0.956   1   29.224 ? 471  LEU B CD2 1 
ATOM   7813 N  N   . ALA B 1 480 ? 5.267   -1.412  1.273   1   20.273 ? 472  ALA B N   1 
ATOM   7814 C  CA  . ALA B 1 480 ? 6.561   -1.103  1.873   1   21.869 ? 472  ALA B CA  1 
ATOM   7815 C  C   . ALA B 1 480 ? 6.327   -0.694  3.321   1   20.678 ? 472  ALA B C   1 
ATOM   7816 O  O   . ALA B 1 480 ? 5.274   -0.115  3.629   1   22.171 ? 472  ALA B O   1 
ATOM   7817 C  CB  . ALA B 1 480 ? 7.246   0.041   1.118   1   22.83  ? 472  ALA B CB  1 
ATOM   7818 N  N   . ILE B 1 481 ? 7.35    -0.888  4.155   1   19.725 ? 473  ILE B N   1 
ATOM   7819 C  CA  . ILE B 1 481 ? 7.294   -0.431  5.545   1   20.111 ? 473  ILE B CA  1 
ATOM   7820 C  C   . ILE B 1 481 ? 7.685   1.047   5.611   1   20.338 ? 473  ILE B C   1 
ATOM   7821 O  O   . ILE B 1 481 ? 8.763   1.417   5.116   1   20.269 ? 473  ILE B O   1 
ATOM   7822 C  CB  . ILE B 1 481 ? 8.231   -1.269  6.458   1   21.709 ? 473  ILE B CB  1 
ATOM   7823 C  CG1 . ILE B 1 481 ? 7.927   -2.796  6.369   1   23.765 ? 473  ILE B CG1 1 
ATOM   7824 C  CG2 . ILE B 1 481 ? 8.191   -0.768  7.925   1   20.184 ? 473  ILE B CG2 1 
ATOM   7825 C  CD1 . ILE B 1 481 ? 6.485   -3.201  6.649   1   24.364 ? 473  ILE B CD1 1 
ATOM   7826 N  N   . VAL B 1 482 ? 6.854   1.838   6.305   1   21.319 ? 474  VAL B N   1 
ATOM   7827 C  CA  . VAL B 1 482 ? 7.121   3.246   6.559   1   20.917 ? 474  VAL B CA  1 
ATOM   7828 C  C   . VAL B 1 482 ? 7.455   3.409   8.041   1   21.455 ? 474  VAL B C   1 
ATOM   7829 O  O   . VAL B 1 482 ? 6.726   2.892   8.888   1   22.678 ? 474  VAL B O   1 
ATOM   7830 C  CB  . VAL B 1 482 ? 5.928   4.141   6.182   1   22.117 ? 474  VAL B CB  1 
ATOM   7831 C  CG1 . VAL B 1 482 ? 6.195   5.6     6.563   1   21.851 ? 474  VAL B CG1 1 
ATOM   7832 C  CG2 . VAL B 1 482 ? 5.602   4.03    4.684   1   23.681 ? 474  VAL B CG2 1 
ATOM   7833 N  N   . ASP B 1 483 ? 8.565   4.114   8.317   1   21.889 ? 475  ASP B N   1 
ATOM   7834 C  CA  . ASP B 1 483 ? 8.882   4.55    9.676   1   22.495 ? 475  ASP B CA  1 
ATOM   7835 C  C   . ASP B 1 483 ? 8.276   5.925   9.908   1   22.333 ? 475  ASP B C   1 
ATOM   7836 O  O   . ASP B 1 483 ? 8.683   6.876   9.255   1   22.634 ? 475  ASP B O   1 
ATOM   7837 C  CB  . ASP B 1 483 ? 10.373  4.654   9.914   1   25.382 ? 475  ASP B CB  1 
ATOM   7838 C  CG  . ASP B 1 483 ? 11.104  3.376   9.541   1   31.876 ? 475  ASP B CG  1 
ATOM   7839 O  OD1 . ASP B 1 483 ? 11.396  3.201   8.316   1   32.409 ? 475  ASP B OD1 1 
ATOM   7840 O  OD2 . ASP B 1 483 ? 11.278  2.544   10.449  1   34.944 ? 475  ASP B OD2 1 
ATOM   7841 N  N   . ARG B 1 484 ? 7.304   6.005   10.816  1   24.903 ? 476  ARG B N   1 
ATOM   7842 C  CA  . ARG B 1 484 ? 6.694   7.272   11.195  1   25.267 ? 476  ARG B CA  1 
ATOM   7843 C  C   . ARG B 1 484 ? 7.54    7.782   12.356  1   30.524 ? 476  ARG B C   1 
ATOM   7844 O  O   . ARG B 1 484 ? 7.295   7.438   13.517  1   30.134 ? 476  ARG B O   1 
ATOM   7845 C  CB  . ARG B 1 484 ? 5.227   7.01    11.561  1   26.361 ? 476  ARG B CB  1 
ATOM   7846 C  CG  . ARG B 1 484 ? 4.302   6.457   10.488  1   22.164 ? 476  ARG B CG  1 
ATOM   7847 C  CD  . ARG B 1 484 ? 4.195   7.36    9.253   1   27.236 ? 476  ARG B CD  1 
ATOM   7848 N  NE  . ARG B 1 484 ? 3.638   8.672   9.625   1   27.02  ? 476  ARG B NE  1 
ATOM   7849 C  CZ  . ARG B 1 484 ? 2.322   8.917   9.685   1   26.803 ? 476  ARG B CZ  1 
ATOM   7850 N  NH1 . ARG B 1 484 ? 1.418   8.011   9.327   1   24.405 ? 476  ARG B NH1 1 
ATOM   7851 N  NH2 . ARG B 1 484 ? 1.912   10.113  10.053  1   27.512 ? 476  ARG B NH2 1 
ATOM   7852 N  N   . LEU B 1 485 ? 8.63    8.488   12.028  1   28.62  ? 477  LEU B N   1 
ATOM   7853 C  CA  . LEU B 1 485 ? 9.714   8.699   12.985  1   29.652 ? 477  LEU B CA  1 
ATOM   7854 C  C   . LEU B 1 485 ? 9.292   9.544   14.192  1   35.541 ? 477  LEU B C   1 
ATOM   7855 O  O   . LEU B 1 485 ? 9.884   9.434   15.257  1   40.9   ? 477  LEU B O   1 
ATOM   7856 C  CB  . LEU B 1 485 ? 10.908  9.347   12.301  1   28.643 ? 477  LEU B CB  1 
ATOM   7857 C  CG  . LEU B 1 485 ? 11.622  8.529   11.228  1   33.647 ? 477  LEU B CG  1 
ATOM   7858 C  CD1 . LEU B 1 485 ? 12.621  9.526   10.587  1   30.063 ? 477  LEU B CD1 1 
ATOM   7859 C  CD2 . LEU B 1 485 ? 12.301  7.308   11.875  1   31.937 ? 477  LEU B CD2 1 
ATOM   7860 N  N   . ASP B 1 486 ? 8.318   10.419  14.01   1   33.283 ? 478  ASP B N   1 
ATOM   7861 C  CA  . ASP B 1 486 ? 7.867   11.253  15.116  1   42.976 ? 478  ASP B CA  1 
ATOM   7862 C  C   . ASP B 1 486 ? 6.758   10.564  15.922  1   49.759 ? 478  ASP B C   1 
ATOM   7863 O  O   . ASP B 1 486 ? 6.336   11.092  16.954  1   43.738 ? 478  ASP B O   1 
ATOM   7864 C  CB  . ASP B 1 486 ? 7.465   12.625  14.606  1   46.243 ? 478  ASP B CB  1 
ATOM   7865 C  CG  . ASP B 1 486 ? 6.442   12.62   13.48   1   53.171 ? 478  ASP B CG  1 
ATOM   7866 O  OD1 . ASP B 1 486 ? 6.098   11.52   12.981  1   54.46  ? 478  ASP B OD1 1 
ATOM   7867 O  OD2 . ASP B 1 486 ? 6.011   13.722  13.103  1   64.872 ? 478  ASP B OD2 1 
ATOM   7868 N  N   . LEU B 1 487 ? 6.317   9.37    15.481  1   50.243 ? 479  LEU B N   1 
ATOM   7869 C  CA  . LEU B 1 487 ? 5.212   8.665   16.117  1   41.176 ? 479  LEU B CA  1 
ATOM   7870 C  C   . LEU B 1 487 ? 5.68    7.422   16.868  1   36.591 ? 479  LEU B C   1 
ATOM   7871 O  O   . LEU B 1 487 ? 4.833   6.764   17.474  1   38.307 ? 479  LEU B O   1 
ATOM   7872 C  CB  . LEU B 1 487 ? 4.089   8.377   15.111  1   36.42  ? 479  LEU B CB  1 
ATOM   7873 C  CG  . LEU B 1 487 ? 3.408   9.58    14.456  1   39.383 ? 479  LEU B CG  1 
ATOM   7874 C  CD1 . LEU B 1 487 ? 2.313   9.138   13.516  1   36.347 ? 479  LEU B CD1 1 
ATOM   7875 C  CD2 . LEU B 1 487 ? 2.811   10.547  15.482  1   45.589 ? 479  LEU B CD2 1 
ATOM   7876 N  N   . ASN B 1 488 ? 6.986   7.079   16.816  1   35.035 ? 480  ASN B N   1 
ATOM   7877 C  CA  . ASN B 1 488 ? 7.524   5.789   17.28   1   38.532 ? 480  ASN B CA  1 
ATOM   7878 C  C   . ASN B 1 488 ? 6.632   4.643   16.79   1   29.756 ? 480  ASN B C   1 
ATOM   7879 O  O   . ASN B 1 488 ? 6.297   3.75    17.572  1   30.487 ? 480  ASN B O   1 
ATOM   7880 C  CB  . ASN B 1 488 ? 7.84    5.712   18.795  1   40.425 ? 480  ASN B CB  1 
ATOM   7881 C  CG  . ASN B 1 488 ? 8.643   4.496   19.313  1   54.782 ? 480  ASN B CG  1 
ATOM   7882 O  OD1 . ASN B 1 488 ? 9.569   3.966   18.676  1   45.051 ? 480  ASN B OD1 1 
ATOM   7883 N  ND2 . ASN B 1 488 ? 8.352   4.014   20.52   1   45.691 ? 480  ASN B ND2 1 
ATOM   7884 N  N   . ARG B 1 489 ? 6.269   4.638   15.493  1   26.282 ? 481  ARG B N   1 
ATOM   7885 C  CA  . ARG B 1 489 ? 5.585   3.463   14.983  1   21.655 ? 481  ARG B CA  1 
ATOM   7886 C  C   . ARG B 1 489 ? 5.986   3.176   13.535  1   21.03  ? 481  ARG B C   1 
ATOM   7887 O  O   . ARG B 1 489 ? 6.571   4.027   12.845  1   22.433 ? 481  ARG B O   1 
ATOM   7888 C  CB  . ARG B 1 489 ? 4.052   3.57    15.135  1   23.372 ? 481  ARG B CB  1 
ATOM   7889 C  CG  . ARG B 1 489 ? 3.328   4.419   14.114  1   26.914 ? 481  ARG B CG  1 
ATOM   7890 C  CD  . ARG B 1 489 ? 1.826   4.291   14.375  1   30.919 ? 481  ARG B CD  1 
ATOM   7891 N  NE  . ARG B 1 489 ? 1.179   5.029   13.288  1   36.078 ? 481  ARG B NE  1 
ATOM   7892 C  CZ  . ARG B 1 489 ? 0.39    6.061   13.495  1   36.235 ? 481  ARG B CZ  1 
ATOM   7893 N  NH1 . ARG B 1 489 ? 0.114   6.456   14.741  1   36.208 ? 481  ARG B NH1 1 
ATOM   7894 N  NH2 . ARG B 1 489 ? -0.115  6.687   12.456  1   41.211 ? 481  ARG B NH2 1 
ATOM   7895 N  N   . SER B 1 490 ? 5.66    1.96    13.115  1   19.754 ? 482  SER B N   1 
ATOM   7896 C  CA  . SER B 1 490 ? 5.913   1.503   11.757  1   20.519 ? 482  SER B CA  1 
ATOM   7897 C  C   . SER B 1 490 ? 4.562   1.181   11.124  1   22.185 ? 482  SER B C   1 
ATOM   7898 O  O   . SER B 1 490 ? 3.621   0.854   11.849  1   21.174 ? 482  SER B O   1 
ATOM   7899 C  CB  . SER B 1 490 ? 6.841   0.303   11.728  1   19.987 ? 482  SER B CB  1 
ATOM   7900 O  OG  . SER B 1 490 ? 8.13    0.616   12.267  1   21.189 ? 482  SER B OG  1 
ATOM   7901 N  N   . GLU B 1 491 ? 4.496   1.273   9.784   1   20.88  ? 483  GLU B N   1 
ATOM   7902 C  CA  . GLU B 1 491 ? 3.245   1.089   9.069   1   20.902 ? 483  GLU B CA  1 
ATOM   7903 C  C   . GLU B 1 491 ? 3.581   0.375   7.78    1   20.78  ? 483  GLU B C   1 
ATOM   7904 O  O   . GLU B 1 491 ? 4.719   0.45    7.338   1   23.877 ? 483  GLU B O   1 
ATOM   7905 C  CB  . GLU B 1 491 ? 2.57    2.418   8.671   1   23.727 ? 483  GLU B CB  1 
ATOM   7906 C  CG  . GLU B 1 491 ? 2.124   3.207   9.888   1   27.691 ? 483  GLU B CG  1 
ATOM   7907 C  CD  . GLU B 1 491 ? 1.387   4.507   9.61    1   27.317 ? 483  GLU B CD  1 
ATOM   7908 O  OE1 . GLU B 1 491 ? 1.509   5.128   8.528   1   25.849 ? 483  GLU B OE1 1 
ATOM   7909 O  OE2 . GLU B 1 491 ? 0.711   4.869   10.564  1   27.03  ? 483  GLU B OE2 1 
ATOM   7910 N  N   . VAL B 1 492 ? 2.599   -0.32   7.2     1   19.127 ? 484  VAL B N   1 
ATOM   7911 C  CA  . VAL B 1 492 ? 2.781   -0.847  5.848   1   19.962 ? 484  VAL B CA  1 
ATOM   7912 C  C   . VAL B 1 492 ? 1.93    0.046   4.963   1   21.617 ? 484  VAL B C   1 
ATOM   7913 O  O   . VAL B 1 492 ? 0.737   0.116   5.176   1   23.999 ? 484  VAL B O   1 
ATOM   7914 C  CB  . VAL B 1 492 ? 2.383   -2.325  5.644   1   20.255 ? 484  VAL B CB  1 
ATOM   7915 C  CG1 . VAL B 1 492 ? 2.837   -2.863  4.276   1   22.45  ? 484  VAL B CG1 1 
ATOM   7916 C  CG2 . VAL B 1 492 ? 2.909   -3.234  6.771   1   22.969 ? 484  VAL B CG2 1 
ATOM   7917 N  N   . VAL B 1 493 ? 2.542   0.663   3.948   1   21.846 ? 485  VAL B N   1 
ATOM   7918 C  CA  . VAL B 1 493 ? 1.715   1.387   2.994   1   25.458 ? 485  VAL B CA  1 
ATOM   7919 C  C   . VAL B 1 493 ? 1.374   0.439   1.84    1   22.721 ? 485  VAL B C   1 
ATOM   7920 O  O   . VAL B 1 493 ? 2.167   -0.439  1.508   1   21.923 ? 485  VAL B O   1 
ATOM   7921 C  CB  . VAL B 1 493 ? 2.466   2.669   2.58    1   27.289 ? 485  VAL B CB  1 
ATOM   7922 C  CG1 . VAL B 1 493 ? 3.684   2.423   1.683   1   26.061 ? 485  VAL B CG1 1 
ATOM   7923 C  CG2 . VAL B 1 493 ? 1.557   3.682   1.924   1   36.196 ? 485  VAL B CG2 1 
ATOM   7924 N  N   . VAL B 1 494 ? 0.188   0.645   1.242   1   22.033 ? 486  VAL B N   1 
ATOM   7925 C  CA  . VAL B 1 494 ? -0.265  -0.07   0.071   1   22.831 ? 486  VAL B CA  1 
ATOM   7926 C  C   . VAL B 1 494 ? -0.581  0.954   -1.013  1   24.709 ? 486  VAL B C   1 
ATOM   7927 O  O   . VAL B 1 494 ? -1.336  1.891   -0.782  1   23.316 ? 486  VAL B O   1 
ATOM   7928 C  CB  . VAL B 1 494 ? -1.489  -0.968  0.363   1   24.222 ? 486  VAL B CB  1 
ATOM   7929 C  CG1 . VAL B 1 494 ? -1.872  -1.796  -0.855  1   23.356 ? 486  VAL B CG1 1 
ATOM   7930 C  CG2 . VAL B 1 494 ? -1.26   -1.899  1.548   1   24.463 ? 486  VAL B CG2 1 
ATOM   7931 N  N   . ILE B 1 495 ? 0.044   0.773   -2.182  1   25.218 ? 487  ILE B N   1 
ATOM   7932 C  CA  . ILE B 1 495 ? -0.032  1.733   -3.279  1   24.862 ? 487  ILE B CA  1 
ATOM   7933 C  C   . ILE B 1 495 ? -0.547  0.958   -4.482  1   26.963 ? 487  ILE B C   1 
ATOM   7934 O  O   . ILE B 1 495 ? -0.054  -0.11   -4.796  1   23.666 ? 487  ILE B O   1 
ATOM   7935 C  CB  . ILE B 1 495 ? 1.343   2.383   -3.555  1   24.964 ? 487  ILE B CB  1 
ATOM   7936 C  CG1 . ILE B 1 495 ? 1.853   3.227   -2.384  1   22.415 ? 487  ILE B CG1 1 
ATOM   7937 C  CG2 . ILE B 1 495 ? 1.344   3.193   -4.859  1   25.624 ? 487  ILE B CG2 1 
ATOM   7938 C  CD1 . ILE B 1 495 ? 3.383   3.368   -2.368  1   23.451 ? 487  ILE B CD1 1 
ATOM   7939 N  N   . ASP B 1 496 ? -1.589  1.487   -5.127  1   25.314 ? 488  ASP B N   1 
ATOM   7940 C  CA  . ASP B 1 496 ? -1.999  0.933   -6.421  1   24.996 ? 488  ASP B CA  1 
ATOM   7941 C  C   . ASP B 1 496 ? -1.139  1.584   -7.509  1   25.573 ? 488  ASP B C   1 
ATOM   7942 O  O   . ASP B 1 496 ? -1      2.802   -7.539  1   26.532 ? 488  ASP B O   1 
ATOM   7943 C  CB  . ASP B 1 496 ? -3.496  1.157   -6.592  1   25.365 ? 488  ASP B CB  1 
ATOM   7944 C  CG  . ASP B 1 496 ? -4.104  0.495   -7.81   1   29.285 ? 488  ASP B CG  1 
ATOM   7945 O  OD1 . ASP B 1 496 ? -3.448  0.538   -8.859  1   26.438 ? 488  ASP B OD1 1 
ATOM   7946 O  OD2 . ASP B 1 496 ? -5.208  -0.08   -7.682  1   30.025 ? 488  ASP B OD2 1 
ATOM   7947 N  N   . THR B 1 497 ? -0.519  0.774   -8.387  1   26.816 ? 489  THR B N   1 
ATOM   7948 C  CA  . THR B 1 497 ? 0.348   1.28    -9.465  1   27.49  ? 489  THR B CA  1 
ATOM   7949 C  C   . THR B 1 497 ? -0.413  2.16    -10.478 1   29.803 ? 489  THR B C   1 
ATOM   7950 O  O   . THR B 1 497 ? 0.22    2.95    -11.183 1   29.731 ? 489  THR B O   1 
ATOM   7951 C  CB  . THR B 1 497 ? 1.123   0.169   -10.193 1   26.184 ? 489  THR B CB  1 
ATOM   7952 O  OG1 . THR B 1 497 ? 0.128   -0.684  -10.773 1   30.306 ? 489  THR B OG1 1 
ATOM   7953 C  CG2 . THR B 1 497 ? 2.06    -0.614  -9.281  1   26.513 ? 489  THR B CG2 1 
ATOM   7954 N  N   . ARG B 1 498 ? -1.745  2.086   -10.483 1   27.815 ? 490  ARG B N   1 
ATOM   7955 C  CA  . ARG B 1 498 ? -2.569  2.98    -11.296 1   33.671 ? 490  ARG B CA  1 
ATOM   7956 C  C   . ARG B 1 498 ? -2.492  4.421   -10.801 1   35.054 ? 490  ARG B C   1 
ATOM   7957 O  O   . ARG B 1 498 ? -2.747  5.336   -11.578 1   34.802 ? 490  ARG B O   1 
ATOM   7958 C  CB  . ARG B 1 498 ? -4.032  2.549   -11.383 1   36.671 ? 490  ARG B CB  1 
ATOM   7959 C  CG  . ARG B 1 498 ? -4.312  1.275   -12.159 1   41.972 ? 490  ARG B CG  1 
ATOM   7960 C  CD  . ARG B 1 498 ? -5.773  1.092   -11.804 1   46.329 ? 490  ARG B CD  1 
ATOM   7961 N  NE  . ARG B 1 498 ? -6.321  -0.209  -12.194 1   56.536 ? 490  ARG B NE  1 
ATOM   7962 C  CZ  . ARG B 1 498 ? -7.513  -0.719  -11.864 1   61.371 ? 490  ARG B CZ  1 
ATOM   7963 N  NH1 . ARG B 1 498 ? -8.354  -0.058  -11.085 1   56.313 ? 490  ARG B NH1 1 
ATOM   7964 N  NH2 . ARG B 1 498 ? -7.853  -1.918  -12.315 1   62.733 ? 490  ARG B NH2 1 
ATOM   7965 N  N   . ASP B 1 499 ? -2.151  4.636   -9.514  1   32.864 ? 491  ASP B N   1 
ATOM   7966 C  CA  . ASP B 1 499 ? -1.773  5.962   -9.062  1   33.746 ? 491  ASP B CA  1 
ATOM   7967 C  C   . ASP B 1 499 ? -0.65   5.834   -8.047  1   32.788 ? 491  ASP B C   1 
ATOM   7968 O  O   . ASP B 1 499 ? -0.915  5.798   -6.846  1   32.002 ? 491  ASP B O   1 
ATOM   7969 C  CB  . ASP B 1 499 ? -2.939  6.825   -8.6    1   33.617 ? 491  ASP B CB  1 
ATOM   7970 C  CG  . ASP B 1 499 ? -2.518  8.223   -8.161  1   35.271 ? 491  ASP B CG  1 
ATOM   7971 O  OD1 . ASP B 1 499 ? -1.304  8.626   -8.342  1   37.834 ? 491  ASP B OD1 1 
ATOM   7972 O  OD2 . ASP B 1 499 ? -3.377  8.912   -7.598  1   39.734 ? 491  ASP B OD2 1 
ATOM   7973 N  N   . PHE B 1 500 ? 0.589   5.836   -8.551  1   31.444 ? 492  PHE B N   1 
ATOM   7974 C  CA  . PHE B 1 500 ? 1.738   5.51    -7.709  1   27.407 ? 492  PHE B CA  1 
ATOM   7975 C  C   . PHE B 1 500 ? 1.99    6.567   -6.635  1   30.392 ? 492  PHE B C   1 
ATOM   7976 O  O   . PHE B 1 500 ? 2.682   6.283   -5.653  1   29.437 ? 492  PHE B O   1 
ATOM   7977 C  CB  . PHE B 1 500 ? 2.973   5.256   -8.582  1   26.464 ? 492  PHE B CB  1 
ATOM   7978 C  CG  . PHE B 1 500 ? 4.079   4.518   -7.823  1   29.19  ? 492  PHE B CG  1 
ATOM   7979 C  CD1 . PHE B 1 500 ? 3.939   3.153   -7.506  1   26.701 ? 492  PHE B CD1 1 
ATOM   7980 C  CD2 . PHE B 1 500 ? 5.241   5.194   -7.42   1   26.949 ? 492  PHE B CD2 1 
ATOM   7981 C  CE1 . PHE B 1 500 ? 4.943   2.479   -6.798  1   28.342 ? 492  PHE B CE1 1 
ATOM   7982 C  CE2 . PHE B 1 500 ? 6.233   4.508   -6.716  1   26.39  ? 492  PHE B CE2 1 
ATOM   7983 C  CZ  . PHE B 1 500 ? 6.091   3.158   -6.422  1   28.291 ? 492  PHE B CZ  1 
ATOM   7984 N  N   . THR B 1 501 ? 1.441   7.795   -6.802  1   27.147 ? 493  THR B N   1 
ATOM   7985 C  CA  . THR B 1 501 ? 1.796   8.886   -5.902  1   28.211 ? 493  THR B CA  1 
ATOM   7986 C  C   . THR B 1 501 ? 0.994   8.815   -4.589  1   27.886 ? 493  THR B C   1 
ATOM   7987 O  O   . THR B 1 501 ? 1.311   9.539   -3.652  1   31.876 ? 493  THR B O   1 
ATOM   7988 C  CB  . THR B 1 501 ? 1.695   10.257  -6.597  1   31.264 ? 493  THR B CB  1 
ATOM   7989 O  OG1 . THR B 1 501 ? 0.303   10.521  -6.637  1   31.223 ? 493  THR B OG1 1 
ATOM   7990 C  CG2 . THR B 1 501 ? 2.299   10.275  -7.995  1   29.129 ? 493  THR B CG2 1 
ATOM   7991 N  N   . LYS B 1 502 ? -0.024  7.952   -4.536  1   28.125 ? 494  LYS B N   1 
ATOM   7992 C  CA  . LYS B 1 502 ? -0.981  7.904   -3.431  1   31.069 ? 494  LYS B CA  1 
ATOM   7993 C  C   . LYS B 1 502 ? -1.069  6.51    -2.819  1   30.51  ? 494  LYS B C   1 
ATOM   7994 O  O   . LYS B 1 502 ? -1.231  5.511   -3.53   1   28.964 ? 494  LYS B O   1 
ATOM   7995 C  CB  . LYS B 1 502 ? -2.369  8.397   -3.885  1   36.544 ? 494  LYS B CB  1 
ATOM   7996 C  CG  . LYS B 1 502 ? -2.56   9.923   -4.094  1   50.444 ? 494  LYS B CG  1 
ATOM   7997 C  CD  . LYS B 1 502 ? -2.02   10.878  -3.018  1   57.256 ? 494  LYS B CD  1 
ATOM   7998 C  CE  . LYS B 1 502 ? -2.407  12.335  -3.041  1   64.445 ? 494  LYS B CE  1 
ATOM   7999 N  NZ  . LYS B 1 502 ? -1.812  13.211  -4.064  1   44.207 ? 494  LYS B NZ  1 
ATOM   8000 N  N   . ALA B 1 503 ? -1.042  6.456   -1.475  1   28.183 ? 495  ALA B N   1 
ATOM   8001 C  CA  . ALA B 1 503 ? -1.381  5.229   -0.769  1   28.216 ? 495  ALA B CA  1 
ATOM   8002 C  C   . ALA B 1 503 ? -2.897  5.022   -0.761  1   31.607 ? 495  ALA B C   1 
ATOM   8003 O  O   . ALA B 1 503 ? -3.648  5.964   -0.49   1   31.191 ? 495  ALA B O   1 
ATOM   8004 C  CB  . ALA B 1 503 ? -0.911  5.341   0.67    1   27.956 ? 495  ALA B CB  1 
ATOM   8005 N  N   . VAL B 1 504 ? -3.322  3.788   -1.029  1   26.392 ? 496  VAL B N   1 
ATOM   8006 C  CA  . VAL B 1 504 ? -4.723  3.397   -0.892  1   29.546 ? 496  VAL B CA  1 
ATOM   8007 C  C   . VAL B 1 504 ? -5.023  2.953   0.541   1   30.582 ? 496  VAL B C   1 
ATOM   8008 O  O   . VAL B 1 504 ? -6.172  3.031   0.976   1   27.445 ? 496  VAL B O   1 
ATOM   8009 C  CB  . VAL B 1 504 ? -5.226  2.355   -1.905  1   32.048 ? 496  VAL B CB  1 
ATOM   8010 C  CG1 . VAL B 1 504 ? -5.196  2.932   -3.316  1   34.378 ? 496  VAL B CG1 1 
ATOM   8011 C  CG2 . VAL B 1 504 ? -4.476  1.022   -1.849  1   32.735 ? 496  VAL B CG2 1 
ATOM   8012 N  N   . ALA B 1 505 ? -4.013  2.432   1.244   1   28.475 ? 497  ALA B N   1 
ATOM   8013 C  CA  . ALA B 1 505 ? -4.246  1.919   2.584   1   23.019 ? 497  ALA B CA  1 
ATOM   8014 C  C   . ALA B 1 505 ? -2.956  1.99    3.371   1   26.4   ? 497  ALA B C   1 
ATOM   8015 O  O   . ALA B 1 505 ? -1.884  2.046   2.786   1   23.408 ? 497  ALA B O   1 
ATOM   8016 C  CB  . ALA B 1 505 ? -4.755  0.518   2.56    1   23.363 ? 497  ALA B CB  1 
ATOM   8017 N  N   . ALA B 1 506 ? -3.093  1.984   4.697   1   25.398 ? 498  ALA B N   1 
ATOM   8018 C  CA  . ALA B 1 506 ? -1.944  1.88    5.575   1   25.55  ? 498  ALA B CA  1 
ATOM   8019 C  C   . ALA B 1 506 ? -2.287  0.867   6.663   1   27.389 ? 498  ALA B C   1 
ATOM   8020 O  O   . ALA B 1 506 ? -3.388  0.901   7.213   1   31.719 ? 498  ALA B O   1 
ATOM   8021 C  CB  . ALA B 1 506 ? -1.59   3.224   6.149   1   26.281 ? 498  ALA B CB  1 
ATOM   8022 N  N   . VAL B 1 507 ? -1.364  -0.072  6.908   1   21.491 ? 499  VAL B N   1 
ATOM   8023 C  CA  . VAL B 1 507 ? -1.525  -1.028  7.979   1   20.684 ? 499  VAL B CA  1 
ATOM   8024 C  C   . VAL B 1 507 ? -0.776  -0.409  9.143   1   20.756 ? 499  VAL B C   1 
ATOM   8025 O  O   . VAL B 1 507 ? 0.414   -0.119  8.997   1   25.258 ? 499  VAL B O   1 
ATOM   8026 C  CB  . VAL B 1 507 ? -0.905  -2.377  7.554   1   21.981 ? 499  VAL B CB  1 
ATOM   8027 C  CG1 . VAL B 1 507 ? -0.995  -3.418  8.677   1   21.232 ? 499  VAL B CG1 1 
ATOM   8028 C  CG2 . VAL B 1 507 ? -1.556  -2.96   6.304   1   22.891 ? 499  VAL B CG2 1 
ATOM   8029 N  N   . GLN B 1 508 ? -1.443  -0.225  10.275  1   19.958 ? 500  GLN B N   1 
ATOM   8030 C  CA  . GLN B 1 508 ? -0.884  0.621   11.317  1   21.298 ? 500  GLN B CA  1 
ATOM   8031 C  C   . GLN B 1 508 ? -0.517  -0.286  12.493  1   23.902 ? 500  GLN B C   1 
ATOM   8032 O  O   . GLN B 1 508 ? -1.401  -0.707  13.237  1   22.388 ? 500  GLN B O   1 
ATOM   8033 C  CB  . GLN B 1 508 ? -1.951  1.679   11.67   1   22.503 ? 500  GLN B CB  1 
ATOM   8034 C  CG  . GLN B 1 508 ? -1.522  2.666   12.756  1   26.065 ? 500  GLN B CG  1 
ATOM   8035 C  CD  . GLN B 1 508 ? -2.618  3.648   13.142  1   27.758 ? 500  GLN B CD  1 
ATOM   8036 O  OE1 . GLN B 1 508 ? -3.461  4.03    12.311  1   27.755 ? 500  GLN B OE1 1 
ATOM   8037 N  NE2 . GLN B 1 508 ? -2.635  4.029   14.417  1   27.451 ? 500  GLN B NE2 1 
ATOM   8038 N  N   . LEU B 1 509 ? 0.793   -0.521  12.696  1   19.133 ? 501  LEU B N   1 
ATOM   8039 C  CA  . LEU B 1 509 ? 1.217   -1.166  13.93   1   17.996 ? 501  LEU B CA  1 
ATOM   8040 C  C   . LEU B 1 509 ? 1.072   -0.232  15.117  1   19.177 ? 501  LEU B C   1 
ATOM   8041 O  O   . LEU B 1 509 ? 1.138   0.991   14.961  1   19.917 ? 501  LEU B O   1 
ATOM   8042 C  CB  . LEU B 1 509 ? 2.64    -1.72   13.809  1   18.343 ? 501  LEU B CB  1 
ATOM   8043 C  CG  . LEU B 1 509 ? 2.809   -2.855  12.785  1   22.3   ? 501  LEU B CG  1 
ATOM   8044 C  CD1 . LEU B 1 509 ? 4.311   -3.082  12.627  1   20.935 ? 501  LEU B CD1 1 
ATOM   8045 C  CD2 . LEU B 1 509 ? 2.142   -4.175  13.221  1   21.62  ? 501  LEU B CD2 1 
ATOM   8046 N  N   . PRO B 1 510 ? 0.922   -0.78   16.349  1   18.542 ? 502  PRO B N   1 
ATOM   8047 C  CA  . PRO B 1 510 ? 0.905   0.026   17.56   1   20.567 ? 502  PRO B CA  1 
ATOM   8048 C  C   . PRO B 1 510 ? 2.299   0.292   18.122  1   23.129 ? 502  PRO B C   1 
ATOM   8049 O  O   . PRO B 1 510 ? 2.441   0.742   19.251  1   24.316 ? 502  PRO B O   1 
ATOM   8050 C  CB  . PRO B 1 510 ? 0.124   -0.851  18.576  1   21.128 ? 502  PRO B CB  1 
ATOM   8051 C  CG  . PRO B 1 510 ? 0.481   -2.252  18.144  1   21.612 ? 502  PRO B CG  1 
ATOM   8052 C  CD  . PRO B 1 510 ? 0.64    -2.199  16.619  1   19.523 ? 502  PRO B CD  1 
ATOM   8053 N  N   . PHE B 1 511 ? 3.305   0.002   17.303  1   19.602 ? 503  PHE B N   1 
ATOM   8054 C  CA  . PHE B 1 511 ? 4.699   0.166   17.713  1   20.166 ? 503  PHE B CA  1 
ATOM   8055 C  C   . PHE B 1 511 ? 5.559   0.275   16.458  1   20.5   ? 503  PHE B C   1 
ATOM   8056 O  O   . PHE B 1 511 ? 5.048   0.118   15.33   1   20.251 ? 503  PHE B O   1 
ATOM   8057 C  CB  . PHE B 1 511 ? 5.106   -0.97   18.674  1   19.857 ? 503  PHE B CB  1 
ATOM   8058 C  CG  . PHE B 1 511 ? 4.811   -2.393  18.22   1   19.477 ? 503  PHE B CG  1 
ATOM   8059 C  CD1 . PHE B 1 511 ? 5.135   -2.872  16.948  1   18.255 ? 503  PHE B CD1 1 
ATOM   8060 C  CD2 . PHE B 1 511 ? 4.184   -3.271  19.096  1   21.999 ? 503  PHE B CD2 1 
ATOM   8061 C  CE1 . PHE B 1 511 ? 4.8     -4.147  16.525  1   20.497 ? 503  PHE B CE1 1 
ATOM   8062 C  CE2 . PHE B 1 511 ? 3.911   -4.592  18.705  1   21.706 ? 503  PHE B CE2 1 
ATOM   8063 C  CZ  . PHE B 1 511 ? 4.182   -5.035  17.415  1   23.419 ? 503  PHE B CZ  1 
ATOM   8064 N  N   . ALA B 1 512 ? 6.855   0.54    16.679  1   21.522 ? 504  ALA B N   1 
ATOM   8065 C  CA  . ALA B 1 512 ? 7.838   0.514   15.602  1   20.044 ? 504  ALA B CA  1 
ATOM   8066 C  C   . ALA B 1 512 ? 8.556   -0.836  15.596  1   21.024 ? 504  ALA B C   1 
ATOM   8067 O  O   . ALA B 1 512 ? 8.773   -1.442  16.648  1   20.921 ? 504  ALA B O   1 
ATOM   8068 C  CB  . ALA B 1 512 ? 8.846   1.645   15.775  1   20.644 ? 504  ALA B CB  1 
ATOM   8069 N  N   . ILE B 1 513 ? 8.969   -1.268  14.399  1   18.093 ? 505  ILE B N   1 
ATOM   8070 C  CA  . ILE B 1 513 ? 9.799   -2.443  14.25   1   19.914 ? 505  ILE B CA  1 
ATOM   8071 C  C   . ILE B 1 513 ? 11.146  -1.959  13.711  1   19.296 ? 505  ILE B C   1 
ATOM   8072 O  O   . ILE B 1 513 ? 11.258  -0.819  13.262  1   18.398 ? 505  ILE B O   1 
ATOM   8073 C  CB  . ILE B 1 513 ? 9.136   -3.546  13.399  1   22.998 ? 505  ILE B CB  1 
ATOM   8074 C  CG1 . ILE B 1 513 ? 8.847   -3.079  11.954  1   23.193 ? 505  ILE B CG1 1 
ATOM   8075 C  CG2 . ILE B 1 513 ? 7.879   -4.101  14.1    1   27.41  ? 505  ILE B CG2 1 
ATOM   8076 C  CD1 . ILE B 1 513 ? 8.249   -4.147  11.028  1   26.851 ? 505  ILE B CD1 1 
ATOM   8077 N  N   . ARG B 1 514 ? 12.172  -2.807  13.795  1   18.606 ? 506  ARG B N   1 
ATOM   8078 C  CA  . ARG B 1 514 ? 13.482  -2.471  13.23   1   19.885 ? 506  ARG B CA  1 
ATOM   8079 C  C   . ARG B 1 514 ? 13.367  -2.11   11.759  1   20.258 ? 506  ARG B C   1 
ATOM   8080 O  O   . ARG B 1 514 ? 12.496  -2.64   11.071  1   19.736 ? 506  ARG B O   1 
ATOM   8081 C  CB  . ARG B 1 514 ? 14.468  -3.642  13.259  1   20.943 ? 506  ARG B CB  1 
ATOM   8082 C  CG  . ARG B 1 514 ? 15.026  -3.808  14.675  1   22.757 ? 506  ARG B CG  1 
ATOM   8083 C  CD  . ARG B 1 514 ? 16.154  -2.773  14.848  1   25.661 ? 506  ARG B CD  1 
ATOM   8084 N  NE  . ARG B 1 514 ? 17.073  -3.084  15.945  1   25.336 ? 506  ARG B NE  1 
ATOM   8085 C  CZ  . ARG B 1 514 ? 18.09   -2.333  16.319  1   24.4   ? 506  ARG B CZ  1 
ATOM   8086 N  NH1 . ARG B 1 514 ? 18.434  -1.247  15.639  1   25.051 ? 506  ARG B NH1 1 
ATOM   8087 N  NH2 . ARG B 1 514 ? 18.784  -2.687  17.401  1   24.969 ? 506  ARG B NH2 1 
ATOM   8088 N  N   . SER B 1 515 ? 14.197  -1.162  11.316  1   19.96  ? 507  SER B N   1 
ATOM   8089 C  CA  . SER B 1 515 ? 14.309  -0.972  9.882   1   21.634 ? 507  SER B CA  1 
ATOM   8090 C  C   . SER B 1 515 ? 15.05   -2.198  9.349   1   22.664 ? 507  SER B C   1 
ATOM   8091 O  O   . SER B 1 515 ? 16.063  -2.6    9.911   1   22.776 ? 507  SER B O   1 
ATOM   8092 C  CB  . SER B 1 515 ? 14.983  0.355   9.539   1   22.404 ? 507  SER B CB  1 
ATOM   8093 O  OG  . SER B 1 515 ? 15.097  0.512   8.114   1   23.439 ? 507  SER B OG  1 
ATOM   8094 N  N   . GLY B 1 516 ? 14.524  -2.794  8.282   1   22.893 ? 508  GLY B N   1 
ATOM   8095 C  CA  . GLY B 1 516 ? 14.996  -4.104  7.851   1   21.284 ? 508  GLY B CA  1 
ATOM   8096 C  C   . GLY B 1 516 ? 15.865  -4.039  6.607   1   22.276 ? 508  GLY B C   1 
ATOM   8097 O  O   . GLY B 1 516 ? 16.371  -2.983  6.229   1   23.296 ? 508  GLY B O   1 
ATOM   8098 N  N   . ILE B 1 517 ? 16.106  -5.215  6.054   1   18.766 ? 509  ILE B N   1 
ATOM   8099 C  CA  . ILE B 1 517 ? 16.955  -5.345  4.891   1   18.826 ? 509  ILE B CA  1 
ATOM   8100 C  C   . ILE B 1 517 ? 16.024  -5.616  3.716   1   19.92  ? 509  ILE B C   1 
ATOM   8101 O  O   . ILE B 1 517 ? 15.484  -4.664  3.135   1   22.886 ? 509  ILE B O   1 
ATOM   8102 C  CB  . ILE B 1 517 ? 18.053  -6.413  5.145   1   20.04  ? 509  ILE B CB  1 
ATOM   8103 C  CG1 . ILE B 1 517 ? 18.681  -6.293  6.557   1   22.881 ? 509  ILE B CG1 1 
ATOM   8104 C  CG2 . ILE B 1 517 ? 19.078  -6.405  4.005   1   19.856 ? 509  ILE B CG2 1 
ATOM   8105 C  CD1 . ILE B 1 517 ? 19.562  -5.082  6.782   1   26.445 ? 509  ILE B CD1 1 
ATOM   8106 N  N   . HIS B 1 518 ? 15.804  -6.899  3.393   1   19.958 ? 510  HIS B N   1 
ATOM   8107 C  CA  . HIS B 1 518 ? 14.866  -7.232  2.34    1   20.461 ? 510  HIS B CA  1 
ATOM   8108 C  C   . HIS B 1 518 ? 13.544  -7.74   2.9     1   22.387 ? 510  HIS B C   1 
ATOM   8109 O  O   . HIS B 1 518 ? 13.405  -8.094  4.076   1   21.586 ? 510  HIS B O   1 
ATOM   8110 C  CB  . HIS B 1 518 ? 15.465  -8.276  1.391   1   19.224 ? 510  HIS B CB  1 
ATOM   8111 C  CG  . HIS B 1 518 ? 16.72   -7.754  0.745   1   21.494 ? 510  HIS B CG  1 
ATOM   8112 N  ND1 . HIS B 1 518 ? 16.665  -6.893  -0.341  1   22.104 ? 510  HIS B ND1 1 
ATOM   8113 C  CD2 . HIS B 1 518 ? 18.046  -7.932  1.041   1   20.989 ? 510  HIS B CD2 1 
ATOM   8114 C  CE1 . HIS B 1 518 ? 17.91   -6.544  -0.681  1   23.462 ? 510  HIS B CE1 1 
ATOM   8115 N  NE2 . HIS B 1 518 ? 18.754  -7.182  0.127   1   19.16  ? 510  HIS B NE2 1 
ATOM   8116 N  N   . GLY B 1 519 ? 12.575  -7.771  1.986   1   21.494 ? 511  GLY B N   1 
ATOM   8117 C  CA  . GLY B 1 519 ? 11.288  -8.408  2.234   1   20.158 ? 511  GLY B CA  1 
ATOM   8118 C  C   . GLY B 1 519 ? 10.816  -8.982  0.912   1   20.372 ? 511  GLY B C   1 
ATOM   8119 O  O   . GLY B 1 519 ? 11.444  -8.706  -0.128  1   20.694 ? 511  GLY B O   1 
ATOM   8120 N  N   . GLN B 1 520 ? 9.756   -9.802  0.964   1   18.478 ? 512  GLN B N   1 
ATOM   8121 C  CA  . GLN B 1 520 ? 9.309   -10.409 -0.269  1   19.755 ? 512  GLN B CA  1 
ATOM   8122 C  C   . GLN B 1 520 ? 7.792   -10.455 -0.201  1   20.521 ? 512  GLN B C   1 
ATOM   8123 O  O   . GLN B 1 520 ? 7.244   -10.722 0.871   1   20.772 ? 512  GLN B O   1 
ATOM   8124 C  CB  . GLN B 1 520 ? 9.819   -11.853 -0.442  1   20.069 ? 512  GLN B CB  1 
ATOM   8125 C  CG  . GLN B 1 520 ? 11.34   -11.991 -0.587  1   20.281 ? 512  GLN B CG  1 
ATOM   8126 C  CD  . GLN B 1 520 ? 11.962  -11.287 -1.782  1   23.365 ? 512  GLN B CD  1 
ATOM   8127 O  OE1 . GLN B 1 520 ? 11.309  -11.089 -2.801  1   25.182 ? 512  GLN B OE1 1 
ATOM   8128 N  NE2 . GLN B 1 520 ? 13.198  -10.805 -1.666  1   21.436 ? 512  GLN B NE2 1 
ATOM   8129 N  N   . TRP B 1 521 ? 7.153   -10.218 -1.357  1   19.659 ? 513  TRP B N   1 
ATOM   8130 C  CA  . TRP B 1 521 ? 5.766   -10.629 -1.496  1   20.037 ? 513  TRP B CA  1 
ATOM   8131 C  C   . TRP B 1 521 ? 5.726   -12.113 -1.872  1   21.402 ? 513  TRP B C   1 
ATOM   8132 O  O   . TRP B 1 521 ? 6.177   -12.496 -2.951  1   22.018 ? 513  TRP B O   1 
ATOM   8133 C  CB  . TRP B 1 521 ? 5.051   -9.789  -2.564  1   18.968 ? 513  TRP B CB  1 
ATOM   8134 C  CG  . TRP B 1 521 ? 3.617   -10.249 -2.655  1   20.105 ? 513  TRP B CG  1 
ATOM   8135 C  CD1 . TRP B 1 521 ? 3.061   -10.984 -3.661  1   22.871 ? 513  TRP B CD1 1 
ATOM   8136 C  CD2 . TRP B 1 521 ? 2.597   -10.038 -1.662  1   24.262 ? 513  TRP B CD2 1 
ATOM   8137 N  NE1 . TRP B 1 521 ? 1.737   -11.251 -3.356  1   24.55  ? 513  TRP B NE1 1 
ATOM   8138 C  CE2 . TRP B 1 521 ? 1.43    -10.693 -2.136  1   23.522 ? 513  TRP B CE2 1 
ATOM   8139 C  CE3 . TRP B 1 521 ? 2.575   -9.38   -0.417  1   24.079 ? 513  TRP B CE3 1 
ATOM   8140 C  CZ2 . TRP B 1 521 ? 0.232   -10.671 -1.414  1   23.836 ? 513  TRP B CZ2 1 
ATOM   8141 C  CZ3 . TRP B 1 521 ? 1.389   -9.381  0.303   1   25.225 ? 513  TRP B CZ3 1 
ATOM   8142 C  CH2 . TRP B 1 521 ? 0.242   -10.031 -0.192  1   22.415 ? 513  TRP B CH2 1 
ATOM   8143 N  N   . ILE B 1 522 ? 5.111   -12.92  -1.004  1   20.197 ? 514  ILE B N   1 
ATOM   8144 C  CA  . ILE B 1 522 ? 4.989   -14.345 -1.252  1   20.761 ? 514  ILE B CA  1 
ATOM   8145 C  C   . ILE B 1 522 ? 3.512   -14.645 -1.484  1   22.926 ? 514  ILE B C   1 
ATOM   8146 O  O   . ILE B 1 522 ? 2.717   -14.584 -0.549  1   22.649 ? 514  ILE B O   1 
ATOM   8147 C  CB  . ILE B 1 522 ? 5.577   -15.183 -0.11   1   19.901 ? 514  ILE B CB  1 
ATOM   8148 C  CG1 . ILE B 1 522 ? 7.068   -14.799 0.234   1   20.93  ? 514  ILE B CG1 1 
ATOM   8149 C  CG2 . ILE B 1 522 ? 5.459   -16.686 -0.399  1   21.409 ? 514  ILE B CG2 1 
ATOM   8150 C  CD1 . ILE B 1 522 ? 8.049   -14.974 -0.906  1   26.101 ? 514  ILE B CD1 1 
ATOM   8151 N  N   . PRO B 1 523 ? 3.124   -15.003 -2.731  1   23.916 ? 515  PRO B N   1 
ATOM   8152 C  CA  . PRO B 1 523 ? 1.722   -15.293 -3.022  1   28.387 ? 515  PRO B CA  1 
ATOM   8153 C  C   . PRO B 1 523 ? 1.208   -16.463 -2.181  1   24.026 ? 515  PRO B C   1 
ATOM   8154 O  O   . PRO B 1 523 ? 1.961   -17.402 -1.845  1   24.671 ? 515  PRO B O   1 
ATOM   8155 C  CB  . PRO B 1 523 ? 1.713   -15.621 -4.537  1   28.696 ? 515  PRO B CB  1 
ATOM   8156 C  CG  . PRO B 1 523 ? 3.06    -15.073 -5.049  1   26.37  ? 515  PRO B CG  1 
ATOM   8157 C  CD  . PRO B 1 523 ? 4.013   -15.17  -3.894  1   24.346 ? 515  PRO B CD  1 
ATOM   8158 N  N   . GLY B 1 524 ? -0.075  -16.36  -1.792  1   25.136 ? 516  GLY B N   1 
ATOM   8159 C  CA  . GLY B 1 524 ? -0.718  -17.415 -1.003  1   23.423 ? 516  GLY B CA  1 
ATOM   8160 C  C   . GLY B 1 524 ? -0.693  -18.767 -1.723  1   25.484 ? 516  GLY B C   1 
ATOM   8161 O  O   . GLY B 1 524 ? -0.495  -19.793 -1.085  1   26.983 ? 516  GLY B O   1 
ATOM   8162 N  N   . GLU B 1 525 ? -0.76   -18.715 -3.068  1   30.942 ? 517  GLU B N   1 
ATOM   8163 C  CA  . GLU B 1 525 ? -0.769  -19.886 -3.943  1   33.86  ? 517  GLU B CA  1 
ATOM   8164 C  C   . GLU B 1 525 ? 0.496   -20.744 -3.807  1   34.204 ? 517  GLU B C   1 
ATOM   8165 O  O   . GLU B 1 525 ? 0.46    -21.948 -4.04   1   32.83  ? 517  GLU B O   1 
ATOM   8166 C  CB  . GLU B 1 525 ? -0.837  -19.421 -5.4    1   40.265 ? 517  GLU B CB  1 
ATOM   8167 C  CG  . GLU B 1 525 ? -2.165  -18.862 -5.9    1   65.618 ? 517  GLU B CG  1 
ATOM   8168 C  CD  . GLU B 1 525 ? -2.003  -18.445 -7.366  1   83.44  ? 517  GLU B CD  1 
ATOM   8169 O  OE1 . GLU B 1 525 ? -0.992  -17.764 -7.674  1   91.342 ? 517  GLU B OE1 1 
ATOM   8170 O  OE2 . GLU B 1 525 ? -2.86   -18.803 -8.213  1   87.781 ? 517  GLU B OE2 1 
ATOM   8171 N  N   . VAL B 1 526 ? 1.636   -20.149 -3.428  1   29.296 ? 518  VAL B N   1 
ATOM   8172 C  CA  . VAL B 1 526 ? 2.89    -20.883 -3.313  1   26.566 ? 518  VAL B CA  1 
ATOM   8173 C  C   . VAL B 1 526 ? 3.243   -21.169 -1.849  1   22.997 ? 518  VAL B C   1 
ATOM   8174 O  O   . VAL B 1 526 ? 4.292   -21.737 -1.567  1   26.314 ? 518  VAL B O   1 
ATOM   8175 C  CB  . VAL B 1 526 ? 4.072   -20.236 -4.064  1   29.534 ? 518  VAL B CB  1 
ATOM   8176 C  CG1 . VAL B 1 526 ? 3.773   -20.046 -5.554  1   30.21  ? 518  VAL B CG1 1 
ATOM   8177 C  CG2 . VAL B 1 526 ? 4.541   -18.92  -3.42   1   31.641 ? 518  VAL B CG2 1 
ATOM   8178 N  N   . THR B 1 527 ? 2.349   -20.804 -0.922  1   23.198 ? 519  THR B N   1 
ATOM   8179 C  CA  . THR B 1 527 ? 2.588   -21.03  0.497   1   23.279 ? 519  THR B CA  1 
ATOM   8180 C  C   . THR B 1 527 ? 1.809   -22.276 0.915   1   24.754 ? 519  THR B C   1 
ATOM   8181 O  O   . THR B 1 527 ? 0.59    -22.255 0.82    1   25.854 ? 519  THR B O   1 
ATOM   8182 C  CB  . THR B 1 527 ? 2.148   -19.812 1.304   1   25.789 ? 519  THR B CB  1 
ATOM   8183 O  OG1 . THR B 1 527 ? 2.764   -18.669 0.721   1   25.49  ? 519  THR B OG1 1 
ATOM   8184 C  CG2 . THR B 1 527 ? 2.491   -19.94  2.789   1   25.265 ? 519  THR B CG2 1 
ATOM   8185 N  N   . PRO B 1 528 ? 2.469   -23.348 1.412   1   24.962 ? 520  PRO B N   1 
ATOM   8186 C  CA  . PRO B 1 528 ? 1.759   -24.535 1.874   1   26.519 ? 520  PRO B CA  1 
ATOM   8187 C  C   . PRO B 1 528 ? 0.764   -24.183 2.969   1   28.664 ? 520  PRO B C   1 
ATOM   8188 O  O   . PRO B 1 528 ? 1.082   -23.381 3.847   1   29.659 ? 520  PRO B O   1 
ATOM   8189 C  CB  . PRO B 1 528 ? 2.846   -25.474 2.369   1   26.508 ? 520  PRO B CB  1 
ATOM   8190 C  CG  . PRO B 1 528 ? 4.067   -24.988 1.617   1   27.825 ? 520  PRO B CG  1 
ATOM   8191 C  CD  . PRO B 1 528 ? 3.935   -23.51  1.52    1   26.532 ? 520  PRO B CD  1 
ATOM   8192 N  N   . ASP B 1 529 ? -0.466  -24.691 2.821   1   26.023 ? 521  ASP B N   1 
ATOM   8193 C  CA  . ASP B 1 529 ? -1.515  -24.562 3.83    1   25.801 ? 521  ASP B CA  1 
ATOM   8194 C  C   . ASP B 1 529 ? -1.971  -23.114 4.042   1   29.669 ? 521  ASP B C   1 
ATOM   8195 O  O   . ASP B 1 529 ? -2.514  -22.824 5.106   1   29.941 ? 521  ASP B O   1 
ATOM   8196 C  CB  . ASP B 1 529 ? -1.122  -25.224 5.154   1   27.191 ? 521  ASP B CB  1 
ATOM   8197 C  CG  . ASP B 1 529 ? -0.575  -26.634 4.986   1   34.973 ? 521  ASP B CG  1 
ATOM   8198 O  OD1 . ASP B 1 529 ? -1.298  -27.473 4.412   1   31.397 ? 521  ASP B OD1 1 
ATOM   8199 O  OD2 . ASP B 1 529 ? 0.603   -26.851 5.303   1   33.27  ? 521  ASP B OD2 1 
ATOM   8200 N  N   . PHE B 1 530 ? -1.772  -22.236 3.044   1   26.153 ? 522  PHE B N   1 
ATOM   8201 C  CA  . PHE B 1 530 ? -2.182  -20.848 3.119   1   25.801 ? 522  PHE B CA  1 
ATOM   8202 C  C   . PHE B 1 530 ? -3.69   -20.791 3.37    1   30.161 ? 522  PHE B C   1 
ATOM   8203 O  O   . PHE B 1 530 ? -4.168  -19.91  4.073   1   29.065 ? 522  PHE B O   1 
ATOM   8204 C  CB  . PHE B 1 530 ? -1.824  -20.022 1.874   1   25.153 ? 522  PHE B CB  1 
ATOM   8205 C  CG  . PHE B 1 530 ? -2.103  -18.528 1.995   1   25.928 ? 522  PHE B CG  1 
ATOM   8206 C  CD1 . PHE B 1 530 ? -1.163  -17.666 2.593   1   22.655 ? 522  PHE B CD1 1 
ATOM   8207 C  CD2 . PHE B 1 530 ? -3.289  -17.98  1.511   1   24.023 ? 522  PHE B CD2 1 
ATOM   8208 C  CE1 . PHE B 1 530 ? -1.422  -16.289 2.645   1   20.532 ? 522  PHE B CE1 1 
ATOM   8209 C  CE2 . PHE B 1 530 ? -3.564  -16.611 1.61    1   25.752 ? 522  PHE B CE2 1 
ATOM   8210 C  CZ  . PHE B 1 530 ? -2.621  -15.768 2.187   1   22.384 ? 522  PHE B CZ  1 
ATOM   8211 N  N   . GLU B 1 531 ? -4.447  -21.733 2.787   1   30.553 ? 523  GLU B N   1 
ATOM   8212 C  CA  . GLU B 1 531 ? -5.906  -21.707 2.888   1   30.782 ? 523  GLU B CA  1 
ATOM   8213 C  C   . GLU B 1 531 ? -6.385  -22.191 4.252   1   30.33  ? 523  GLU B C   1 
ATOM   8214 O  O   . GLU B 1 531 ? -7.511  -21.895 4.618   1   34.436 ? 523  GLU B O   1 
ATOM   8215 C  CB  . GLU B 1 531 ? -6.567  -22.459 1.724   1   30.121 ? 523  GLU B CB  1 
ATOM   8216 C  CG  . GLU B 1 531 ? -6.232  -21.856 0.359   1   35.072 ? 523  GLU B CG  1 
ATOM   8217 C  CD  . GLU B 1 531 ? -6.614  -20.4   0.153   1   41.695 ? 523  GLU B CD  1 
ATOM   8218 O  OE1 . GLU B 1 531 ? -7.668  -19.934 0.64    1   43.132 ? 523  GLU B OE1 1 
ATOM   8219 O  OE2 . GLU B 1 531 ? -5.844  -19.727 -0.549  1   38.851 ? 523  GLU B OE2 1 
ATOM   8220 N  N   . THR B 1 532 ? -5.535  -22.849 5.05    1   30.38  ? 524  THR B N   1 
ATOM   8221 C  CA  . THR B 1 532 ? -6.013  -23.434 6.298   1   34.535 ? 524  THR B CA  1 
ATOM   8222 C  C   . THR B 1 532 ? -5.306  -22.889 7.541   1   36.408 ? 524  THR B C   1 
ATOM   8223 O  O   . THR B 1 532 ? -5.801  -23.062 8.652   1   34.732 ? 524  THR B O   1 
ATOM   8224 C  CB  . THR B 1 532 ? -6.016  -24.957 6.269   1   33.01  ? 524  THR B CB  1 
ATOM   8225 O  OG1 . THR B 1 532 ? -4.66   -25.395 6.225   1   36.519 ? 524  THR B OG1 1 
ATOM   8226 C  CG2 . THR B 1 532 ? -6.863  -25.523 5.137   1   32.547 ? 524  THR B CG2 1 
ATOM   8227 N  N   . LYS B 1 533 ? -4.157  -22.237 7.361   1   32.491 ? 525  LYS B N   1 
ATOM   8228 C  CA  . LYS B 1 533 ? -3.365  -21.783 8.495   1   30.182 ? 525  LYS B CA  1 
ATOM   8229 C  C   . LYS B 1 533 ? -3.169  -20.28  8.37    1   27.215 ? 525  LYS B C   1 
ATOM   8230 O  O   . LYS B 1 533 ? -2.768  -19.775 7.322   1   29.359 ? 525  LYS B O   1 
ATOM   8231 C  CB  . LYS B 1 533 ? -1.996  -22.466 8.552   1   32.035 ? 525  LYS B CB  1 
ATOM   8232 C  CG  . LYS B 1 533 ? -2.033  -23.956 8.797   1   31.57  ? 525  LYS B CG  1 
ATOM   8233 C  CD  . LYS B 1 533 ? -0.655  -24.565 8.903   1   33.73  ? 525  LYS B CD  1 
ATOM   8234 C  CE  . LYS B 1 533 ? -0.74   -26.041 8.954   1   45.666 ? 525  LYS B CE  1 
ATOM   8235 N  NZ  . LYS B 1 533 ? 0.605   -26.53  9.244   1   50.345 ? 525  LYS B NZ  1 
ATOM   8236 N  N   . GLY B 1 534 ? -3.446  -19.568 9.458   1   28.055 ? 526  GLY B N   1 
ATOM   8237 C  CA  . GLY B 1 534 ? -3.145  -18.144 9.454   1   24.289 ? 526  GLY B CA  1 
ATOM   8238 C  C   . GLY B 1 534 ? -1.841  -17.958 10.218  1   22.56  ? 526  GLY B C   1 
ATOM   8239 O  O   . GLY B 1 534 ? -1.306  -18.925 10.757  1   22.475 ? 526  GLY B O   1 
ATOM   8240 N  N   . LEU B 1 535 ? -1.416  -16.696 10.352  1   22.632 ? 527  LEU B N   1 
ATOM   8241 C  CA  . LEU B 1 535 ? -0.244  -16.396 11.177  1   21.382 ? 527  LEU B CA  1 
ATOM   8242 C  C   . LEU B 1 535 ? -0.612  -16.537 12.652  1   21.252 ? 527  LEU B C   1 
ATOM   8243 O  O   . LEU B 1 535 ? 0.266   -16.733 13.459  1   24.939 ? 527  LEU B O   1 
ATOM   8244 C  CB  . LEU B 1 535 ? 0.177   -14.958 10.903  1   21.272 ? 527  LEU B CB  1 
ATOM   8245 C  CG  . LEU B 1 535 ? 0.706   -14.678 9.492   1   20.891 ? 527  LEU B CG  1 
ATOM   8246 C  CD1 . LEU B 1 535 ? 1.163   -13.21  9.49    1   18.675 ? 527  LEU B CD1 1 
ATOM   8247 C  CD2 . LEU B 1 535 ? 1.898   -15.634 9.087   1   20.286 ? 527  LEU B CD2 1 
ATOM   8248 N  N   . VAL B 1 536 ? -1.916  -16.454 12.987  1   21.961 ? 528  VAL B N   1 
ATOM   8249 C  CA  . VAL B 1 536 ? -2.343  -16.562 14.381  1   22.732 ? 528  VAL B CA  1 
ATOM   8250 C  C   . VAL B 1 536 ? -3.298  -17.754 14.462  1   24.68  ? 528  VAL B C   1 
ATOM   8251 O  O   . VAL B 1 536 ? -4.306  -17.767 13.756  1   28.423 ? 528  VAL B O   1 
ATOM   8252 C  CB  . VAL B 1 536 ? -3.065  -15.26  14.816  1   24.223 ? 528  VAL B CB  1 
ATOM   8253 C  CG1 . VAL B 1 536 ? -3.556  -15.317 16.277  1   27.963 ? 528  VAL B CG1 1 
ATOM   8254 C  CG2 . VAL B 1 536 ? -2.234  -13.99  14.591  1   26.753 ? 528  VAL B CG2 1 
ATOM   8255 N  N   . ASP B 1 537 ? -3.035  -18.7   15.368  1   27.654 ? 529  ASP B N   1 
ATOM   8256 C  CA  . ASP B 1 537 ? -3.948  -19.833 15.477  1   29.159 ? 529  ASP B CA  1 
ATOM   8257 C  C   . ASP B 1 537 ? -5.229  -19.393 16.182  1   27.61  ? 529  ASP B C   1 
ATOM   8258 O  O   . ASP B 1 537 ? -5.157  -18.712 17.196  1   30.316 ? 529  ASP B O   1 
ATOM   8259 C  CB  . ASP B 1 537 ? -3.341  -21.022 16.193  1   35.6   ? 529  ASP B CB  1 
ATOM   8260 C  CG  . ASP B 1 537 ? -2.55   -21.979 15.314  1   45.429 ? 529  ASP B CG  1 
ATOM   8261 O  OD1 . ASP B 1 537 ? -2.674  -21.902 14.076  1   46.138 ? 529  ASP B OD1 1 
ATOM   8262 O  OD2 . ASP B 1 537 ? -1.812  -22.801 15.88   1   53.018 ? 529  ASP B OD2 1 
ATOM   8263 N  N   . LEU B 1 538 ? -6.367  -19.779 15.611  1   27.441 ? 530  LEU B N   1 
ATOM   8264 C  CA  . LEU B 1 538 ? -7.665  -19.401 16.138  1   28.289 ? 530  LEU B CA  1 
ATOM   8265 C  C   . LEU B 1 538 ? -7.897  -20.14  17.454  1   26.027 ? 530  LEU B C   1 
ATOM   8266 O  O   . LEU B 1 538 ? -7.484  -21.296 17.643  1   25.49  ? 530  LEU B O   1 
ATOM   8267 C  CB  . LEU B 1 538 ? -8.818  -19.619 15.166  1   32.428 ? 530  LEU B CB  1 
ATOM   8268 C  CG  . LEU B 1 538 ? -8.868  -18.673 13.957  1   36.334 ? 530  LEU B CG  1 
ATOM   8269 C  CD1 . LEU B 1 538 ? -10.113 -19.055 13.178  1   34.876 ? 530  LEU B CD1 1 
ATOM   8270 C  CD2 . LEU B 1 538 ? -8.908  -17.176 14.329  1   33.945 ? 530  LEU B CD2 1 
ATOM   8271 N  N   . PRO B 1 539 ? -8.576  -19.504 18.433  1   24.311 ? 531  PRO B N   1 
ATOM   8272 C  CA  . PRO B 1 539 ? -8.968  -20.239 19.629  1   25.268 ? 531  PRO B CA  1 
ATOM   8273 C  C   . PRO B 1 539 ? -10.028 -21.283 19.265  1   19.759 ? 531  PRO B C   1 
ATOM   8274 O  O   . PRO B 1 539 ? -10.613 -21.227 18.176  1   24.362 ? 531  PRO B O   1 
ATOM   8275 C  CB  . PRO B 1 539 ? -9.385  -19.171 20.634  1   26.712 ? 531  PRO B CB  1 
ATOM   8276 C  CG  . PRO B 1 539 ? -9.623  -17.931 19.791  1   30.667 ? 531  PRO B CG  1 
ATOM   8277 C  CD  . PRO B 1 539 ? -9.034  -18.098 18.416  1   29.189 ? 531  PRO B CD  1 
ATOM   8278 N  N   . LYS B 1 540 ? -10.257 -22.208 20.198  1   23.901 ? 532  LYS B N   1 
ATOM   8279 C  CA  . LYS B 1 540 ? -11.225 -23.277 19.964  1   23.819 ? 532  LYS B CA  1 
ATOM   8280 C  C   . LYS B 1 540 ? -12.635 -22.688 19.886  1   26.115 ? 532  LYS B C   1 
ATOM   8281 O  O   . LYS B 1 540 ? -12.941 -21.641 20.481  1   22.957 ? 532  LYS B O   1 
ATOM   8282 C  CB  . LYS B 1 540 ? -11.04  -24.346 21.051  1   23.948 ? 532  LYS B CB  1 
ATOM   8283 C  CG  . LYS B 1 540 ? -11.558 -23.933 22.427  1   25.55  ? 532  LYS B CG  1 
ATOM   8284 C  CD  . LYS B 1 540 ? -11.513 -25.131 23.377  1   30.428 ? 532  LYS B CD  1 
ATOM   8285 C  CE  . LYS B 1 540 ? -12.018 -24.77  24.753  1   31.829 ? 532  LYS B CE  1 
ATOM   8286 N  NZ  . LYS B 1 540 ? -12.24  -25.982 25.567  1   27.569 ? 532  LYS B NZ  1 
ATOM   8287 N  N   . GLU B 1 541 ? -13.513 -23.393 19.174  1   23.17  ? 533  GLU B N   1 
ATOM   8288 C  CA  . GLU B 1 541 ? -14.883 -22.932 19.053  1   24.714 ? 533  GLU B CA  1 
ATOM   8289 C  C   . GLU B 1 541 ? -15.69  -23.179 20.338  1   23.998 ? 533  GLU B C   1 
ATOM   8290 O  O   . GLU B 1 541 ? -16.489 -22.336 20.73   1   24.951 ? 533  GLU B O   1 
ATOM   8291 C  CB  . GLU B 1 541 ? -15.463 -23.72  17.886  1   26.781 ? 533  GLU B CB  1 
ATOM   8292 C  CG  . GLU B 1 541 ? -16.905 -23.34  17.623  1   30.412 ? 533  GLU B CG  1 
ATOM   8293 C  CD  . GLU B 1 541 ? -17.47  -24.115 16.439  1   42.381 ? 533  GLU B CD  1 
ATOM   8294 O  OE1 . GLU B 1 541 ? -16.891 -25.114 15.942  1   49.535 ? 533  GLU B OE1 1 
ATOM   8295 O  OE2 . GLU B 1 541 ? -18.547 -23.672 16.028  1   50.199 ? 533  GLU B OE2 1 
ATOM   8296 N  N   . GLU B 1 542 ? -15.529 -24.353 20.95   1   24.571 ? 534  GLU B N   1 
ATOM   8297 C  CA  . GLU B 1 542 ? -16.302 -24.784 22.109  1   28.692 ? 534  GLU B CA  1 
ATOM   8298 C  C   . GLU B 1 542 ? -16.167 -23.745 23.224  1   24.513 ? 534  GLU B C   1 
ATOM   8299 O  O   . GLU B 1 542 ? -15.076 -23.255 23.487  1   23.693 ? 534  GLU B O   1 
ATOM   8300 C  CB  . GLU B 1 542 ? -15.703 -26.107 22.57   1   29.803 ? 534  GLU B CB  1 
ATOM   8301 C  CG  . GLU B 1 542 ? -16.193 -26.643 23.909  1   44.831 ? 534  GLU B CG  1 
ATOM   8302 C  CD  . GLU B 1 542 ? -15.45  -27.925 24.278  1   54.96  ? 534  GLU B CD  1 
ATOM   8303 O  OE1 . GLU B 1 542 ? -14.171 -27.993 24.337  1   51.484 ? 534  GLU B OE1 1 
ATOM   8304 O  OE2 . GLU B 1 542 ? -16.22  -28.879 24.524  1   51.826 ? 534  GLU B OE2 1 
ATOM   8305 N  N   . HIS B 1 543 ? -17.295 -23.356 23.822  1   26.126 ? 535  HIS B N   1 
ATOM   8306 C  CA  . HIS B 1 543 ? -17.25  -22.478 24.986  1   24.628 ? 535  HIS B CA  1 
ATOM   8307 C  C   . HIS B 1 543 ? -16.581 -23.177 26.17   1   24.76  ? 535  HIS B C   1 
ATOM   8308 O  O   . HIS B 1 543 ? -16.781 -24.373 26.406  1   25.117 ? 535  HIS B O   1 
ATOM   8309 C  CB  . HIS B 1 543 ? -18.656 -21.999 25.345  1   25.724 ? 535  HIS B CB  1 
ATOM   8310 C  CG  . HIS B 1 543 ? -19.321 -21.173 24.291  1   28.195 ? 535  HIS B CG  1 
ATOM   8311 N  ND1 . HIS B 1 543 ? -18.734 -20.13  23.597  1   27.351 ? 535  HIS B ND1 1 
ATOM   8312 C  CD2 . HIS B 1 543 ? -20.611 -21.235 23.864  1   28.631 ? 535  HIS B CD2 1 
ATOM   8313 C  CE1 . HIS B 1 543 ? -19.621 -19.608 22.739  1   27.493 ? 535  HIS B CE1 1 
ATOM   8314 N  NE2 . HIS B 1 543 ? -20.791 -20.272 22.91   1   27.351 ? 535  HIS B NE2 1 
ATOM   8315 N  N   . TRP B 1 544 ? -15.822 -22.399 26.946  1   22.013 ? 536  TRP B N   1 
ATOM   8316 C  CA  . TRP B 1 544 ? -15.333 -22.838 28.239  1   22.281 ? 536  TRP B CA  1 
ATOM   8317 C  C   . TRP B 1 544 ? -16.483 -22.95  29.222  1   24.322 ? 536  TRP B C   1 
ATOM   8318 O  O   . TRP B 1 544 ? -16.454 -23.829 30.065  1   26.066 ? 536  TRP B O   1 
ATOM   8319 C  CB  . TRP B 1 544 ? -14.331 -21.849 28.85   1   21.614 ? 536  TRP B CB  1 
ATOM   8320 C  CG  . TRP B 1 544 ? -13.086 -21.601 28.048  1   22.549 ? 536  TRP B CG  1 
ATOM   8321 C  CD1 . TRP B 1 544 ? -12.734 -20.446 27.398  1   20.733 ? 536  TRP B CD1 1 
ATOM   8322 C  CD2 . TRP B 1 544 ? -11.98  -22.513 27.899  1   22.394 ? 536  TRP B CD2 1 
ATOM   8323 N  NE1 . TRP B 1 544 ? -11.468 -20.578 26.859  1   23.156 ? 536  TRP B NE1 1 
ATOM   8324 C  CE2 . TRP B 1 544 ? -10.989 -21.837 27.142  1   22.069 ? 536  TRP B CE2 1 
ATOM   8325 C  CE3 . TRP B 1 544 ? -11.731 -23.831 28.315  1   23.433 ? 536  TRP B CE3 1 
ATOM   8326 C  CZ2 . TRP B 1 544 ? -9.764  -22.425 26.813  1   21.23  ? 536  TRP B CZ2 1 
ATOM   8327 C  CZ3 . TRP B 1 544 ? -10.511 -24.4   28.001  1   24.673 ? 536  TRP B CZ3 1 
ATOM   8328 C  CH2 . TRP B 1 544 ? -9.552  -23.721 27.238  1   23.952 ? 536  TRP B CH2 1 
ATOM   8329 N  N   . ALA B 1 545 ? -17.436 -22.001 29.188  1   22.52  ? 537  ALA B N   1 
ATOM   8330 C  CA  . ALA B 1 545 ? -18.379 -21.918 30.295  1   21.252 ? 537  ALA B CA  1 
ATOM   8331 C  C   . ALA B 1 545 ? -19.655 -22.662 29.921  1   19.937 ? 537  ALA B C   1 
ATOM   8332 O  O   . ALA B 1 545 ? -20.023 -22.704 28.741  1   23.333 ? 537  ALA B O   1 
ATOM   8333 C  CB  . ALA B 1 545 ? -18.761 -20.468 30.545  1   20.961 ? 537  ALA B CB  1 
ATOM   8334 N  N   . PRO B 1 546 ? -20.384 -23.216 30.915  1   22.7   ? 538  PRO B N   1 
ATOM   8335 C  CA  . PRO B 1 546 ? -21.689 -23.828 30.648  1   23.059 ? 538  PRO B CA  1 
ATOM   8336 C  C   . PRO B 1 546 ? -22.77  -22.792 30.392  1   24.387 ? 538  PRO B C   1 
ATOM   8337 O  O   . PRO B 1 546 ? -22.669 -21.65  30.846  1   24.604 ? 538  PRO B O   1 
ATOM   8338 C  CB  . PRO B 1 546 ? -21.945 -24.657 31.899  1   25.391 ? 538  PRO B CB  1 
ATOM   8339 C  CG  . PRO B 1 546 ? -21.247 -23.868 32.966  1   22.937 ? 538  PRO B CG  1 
ATOM   8340 C  CD  . PRO B 1 546 ? -20     -23.299 32.34   1   22.056 ? 538  PRO B CD  1 
ATOM   8341 N  N   . LEU B 1 547 ? -23.844 -23.217 29.701  1   25.855 ? 539  LEU B N   1 
ATOM   8342 C  CA  . LEU B 1 547 ? -25.027 -22.403 29.441  1   25.949 ? 539  LEU B CA  1 
ATOM   8343 C  C   . LEU B 1 547 ? -25.56  -21.741 30.718  1   24.069 ? 539  LEU B C   1 
ATOM   8344 O  O   . LEU B 1 547 ? -25.896 -20.553 30.691  1   26.251 ? 539  LEU B O   1 
ATOM   8345 C  CB  . LEU B 1 547 ? -26.092 -23.281 28.769  1   29.044 ? 539  LEU B CB  1 
ATOM   8346 C  CG  . LEU B 1 547 ? -27.33  -22.538 28.24   1   32.789 ? 539  LEU B CG  1 
ATOM   8347 C  CD1 . LEU B 1 547 ? -27.012 -21.692 26.995  1   34.858 ? 539  LEU B CD1 1 
ATOM   8348 C  CD2 . LEU B 1 547 ? -28.49  -23.516 27.974  1   32.873 ? 539  LEU B CD2 1 
ATOM   8349 N  N   . SER B 1 548 ? -25.544 -22.494 31.824  1   24.726 ? 540  SER B N   1 
ATOM   8350 C  CA  . SER B 1 548 ? -26.108 -22.124 33.113  1   26.302 ? 540  SER B CA  1 
ATOM   8351 C  C   . SER B 1 548 ? -25.429 -20.894 33.723  1   24.575 ? 540  SER B C   1 
ATOM   8352 O  O   . SER B 1 548 ? -26.005 -20.258 34.596  1   28.661 ? 540  SER B O   1 
ATOM   8353 C  CB  . SER B 1 548 ? -26.076 -23.267 34.068  1   25.435 ? 540  SER B CB  1 
ATOM   8354 O  OG  . SER B 1 548 ? -24.745 -23.617 34.408  1   30.637 ? 540  SER B OG  1 
ATOM   8355 N  N   . GLN B 1 549 ? -24.208 -20.575 33.261  1   24.054 ? 541  GLN B N   1 
ATOM   8356 C  CA  . GLN B 1 549 ? -23.467 -19.458 33.82   1   22.025 ? 541  GLN B CA  1 
ATOM   8357 C  C   . GLN B 1 549 ? -23.841 -18.122 33.177  1   24.699 ? 541  GLN B C   1 
ATOM   8358 O  O   . GLN B 1 549 ? -23.382 -17.099 33.671  1   23.192 ? 541  GLN B O   1 
ATOM   8359 C  CB  . GLN B 1 549 ? -21.971 -19.761 33.713  1   21.906 ? 541  GLN B CB  1 
ATOM   8360 C  CG  . GLN B 1 549 ? -21.512 -20.715 34.799  1   19.898 ? 541  GLN B CG  1 
ATOM   8361 C  CD  . GLN B 1 549 ? -21.216 -20.015 36.101  1   21.418 ? 541  GLN B CD  1 
ATOM   8362 O  OE1 . GLN B 1 549 ? -20.523 -18.993 36.157  1   22.688 ? 541  GLN B OE1 1 
ATOM   8363 N  NE2 . GLN B 1 549 ? -21.794 -20.516 37.177  1   21.948 ? 541  GLN B NE2 1 
ATOM   8364 N  N   . SER B 1 550 ? -24.596 -18.121 32.057  1   22.472 ? 542  SER B N   1 
ATOM   8365 C  CA  . SER B 1 550 ? -24.917 -16.856 31.4    1   24.178 ? 542  SER B CA  1 
ATOM   8366 C  C   . SER B 1 550 ? -25.727 -15.982 32.353  1   22.224 ? 542  SER B C   1 
ATOM   8367 O  O   . SER B 1 550 ? -26.632 -16.48  33.049  1   23.156 ? 542  SER B O   1 
ATOM   8368 C  CB  . SER B 1 550 ? -25.708 -17.014 30.133  1   31.329 ? 542  SER B CB  1 
ATOM   8369 O  OG  . SER B 1 550 ? -25.825 -15.728 29.537  1   30.262 ? 542  SER B OG  1 
ATOM   8370 N  N   . PRO B 1 551 ? -25.438 -14.663 32.425  1   21.514 ? 543  PRO B N   1 
ATOM   8371 C  CA  . PRO B 1 551 ? -26.282 -13.758 33.194  1   22.258 ? 543  PRO B CA  1 
ATOM   8372 C  C   . PRO B 1 551 ? -27.68  -13.604 32.609  1   23.176 ? 543  PRO B C   1 
ATOM   8373 O  O   . PRO B 1 551 ? -28.612 -13.258 33.322  1   22.928 ? 543  PRO B O   1 
ATOM   8374 C  CB  . PRO B 1 551 ? -25.52  -12.433 33.175  1   21.524 ? 543  PRO B CB  1 
ATOM   8375 C  CG  . PRO B 1 551 ? -24.659 -12.529 31.906  1   22.264 ? 543  PRO B CG  1 
ATOM   8376 C  CD  . PRO B 1 551 ? -24.27  -13.983 31.828  1   22.107 ? 543  PRO B CD  1 
ATOM   8377 N  N   . TYR B 1 552 ? -27.786 -13.843 31.301  1   23.055 ? 544  TYR B N   1 
ATOM   8378 C  CA  . TYR B 1 552 ? -29.024 -13.66  30.554  1   22.199 ? 544  TYR B CA  1 
ATOM   8379 C  C   . TYR B 1 552 ? -29.887 -14.903 30.664  1   21.713 ? 544  TYR B C   1 
ATOM   8380 O  O   . TYR B 1 552 ? -29.418 -16.039 30.525  1   23.398 ? 544  TYR B O   1 
ATOM   8381 C  CB  . TYR B 1 552 ? -28.635 -13.421 29.089  1   20.635 ? 544  TYR B CB  1 
ATOM   8382 C  CG  . TYR B 1 552 ? -29.81  -13.504 28.123  1   22.669 ? 544  TYR B CG  1 
ATOM   8383 C  CD1 . TYR B 1 552 ? -30.699 -12.434 27.98   1   22.125 ? 544  TYR B CD1 1 
ATOM   8384 C  CD2 . TYR B 1 552 ? -29.992 -14.645 27.34   1   26.072 ? 544  TYR B CD2 1 
ATOM   8385 C  CE1 . TYR B 1 552 ? -31.74  -12.505 27.057  1   23.461 ? 544  TYR B CE1 1 
ATOM   8386 C  CE2 . TYR B 1 552 ? -31.025 -14.711 26.413  1   24.04  ? 544  TYR B CE2 1 
ATOM   8387 C  CZ  . TYR B 1 552 ? -31.882 -13.641 26.279  1   26.008 ? 544  TYR B CZ  1 
ATOM   8388 O  OH  . TYR B 1 552 ? -32.94  -13.688 25.412  1   29.7   ? 544  TYR B OH  1 
ATOM   8389 N  N   . ASP B 1 553 ? -31.171 -14.636 30.939  1   22.331 ? 545  ASP B N   1 
ATOM   8390 C  CA  . ASP B 1 553 ? -32.196 -15.655 30.948  1   24.836 ? 545  ASP B CA  1 
ATOM   8391 C  C   . ASP B 1 553 ? -33.257 -15.256 29.922  1   25.227 ? 545  ASP B C   1 
ATOM   8392 O  O   . ASP B 1 553 ? -33.875 -14.204 30.069  1   24.341 ? 545  ASP B O   1 
ATOM   8393 C  CB  . ASP B 1 553 ? -32.741 -15.757 32.363  1   25.533 ? 545  ASP B CB  1 
ATOM   8394 C  CG  . ASP B 1 553 ? -33.914 -16.71  32.573  1   32.405 ? 545  ASP B CG  1 
ATOM   8395 O  OD1 . ASP B 1 553 ? -34.393 -17.343 31.57   1   27.664 ? 545  ASP B OD1 1 
ATOM   8396 O  OD2 . ASP B 1 553 ? -34.342 -16.769 33.749  1   34.234 ? 545  ASP B OD2 1 
ATOM   8397 N  N   . PRO B 1 554 ? -33.53  -16.078 28.88   1   25.22  ? 546  PRO B N   1 
ATOM   8398 C  CA  . PRO B 1 554 ? -34.529 -15.702 27.882  1   24.223 ? 546  PRO B CA  1 
ATOM   8399 C  C   . PRO B 1 554 ? -35.954 -15.569 28.418  1   24.297 ? 546  PRO B C   1 
ATOM   8400 O  O   . PRO B 1 554 ? -36.788 -14.925 27.789  1   25.392 ? 546  PRO B O   1 
ATOM   8401 C  CB  . PRO B 1 554 ? -34.396 -16.744 26.762  1   25.74  ? 546  PRO B CB  1 
ATOM   8402 C  CG  . PRO B 1 554 ? -33.679 -17.891 27.417  1   28.604 ? 546  PRO B CG  1 
ATOM   8403 C  CD  . PRO B 1 554 ? -32.822 -17.322 28.53   1   28.307 ? 546  PRO B CD  1 
ATOM   8404 N  N   . ASP B 1 555 ? -36.2   -16.129 29.61   1   22.933 ? 547  ASP B N   1 
ATOM   8405 C  CA  . ASP B 1 555 ? -37.493 -16.041 30.272  1   27.989 ? 547  ASP B CA  1 
ATOM   8406 C  C   . ASP B 1 555 ? -37.65  -14.799 31.139  1   30.668 ? 547  ASP B C   1 
ATOM   8407 O  O   . ASP B 1 555 ? -38.776 -14.538 31.571  1   29.681 ? 547  ASP B O   1 
ATOM   8408 C  CB  . ASP B 1 555 ? -37.769 -17.314 31.056  1   30.376 ? 547  ASP B CB  1 
ATOM   8409 C  CG  . ASP B 1 555 ? -37.877 -18.546 30.171  1   31.037 ? 547  ASP B CG  1 
ATOM   8410 O  OD1 . ASP B 1 555 ? -38.495 -18.47  29.078  1   28.795 ? 547  ASP B OD1 1 
ATOM   8411 O  OD2 . ASP B 1 555 ? -37.356 -19.568 30.581  1   37.386 ? 547  ASP B OD2 1 
ATOM   8412 N  N   . ALA B 1 556 ? -36.545 -14.093 31.448  1   26.578 ? 548  ALA B N   1 
ATOM   8413 C  CA  . ALA B 1 556 ? -36.577 -12.982 32.391  1   28.815 ? 548  ALA B CA  1 
ATOM   8414 C  C   . ALA B 1 556 ? -37.185 -11.722 31.76   1   27.884 ? 548  ALA B C   1 
ATOM   8415 O  O   . ALA B 1 556 ? -37.451 -10.786 32.557  1   28.682 ? 548  ALA B O   1 
ATOM   8416 C  CB  . ALA B 1 556 ? -35.179 -12.701 32.925  1   28.161 ? 548  ALA B CB  1 
ATOM   8417 O  OXT . ALA B 1 556 ? -37.279 -11.627 30.512  1   27.242 ? 548  ALA B OXT 1 
HETATM 8418 C  CAI . V55 C 2 .   ? -14.062 -1.291  37.507  1   33.533 ? 601  V55 A CAI 1 
HETATM 8419 C  CAG . V55 C 2 .   ? -13.38  -1.929  36.451  1   32.786 ? 601  V55 A CAG 1 
HETATM 8420 C  CAK . V55 C 2 .   ? -14.027 -2.847  35.644  1   31.288 ? 601  V55 A CAK 1 
HETATM 8421 C  CAJ . V55 C 2 .   ? -15.344 -3.236  35.947  1   30.586 ? 601  V55 A CAJ 1 
HETATM 8422 C  CAF . V55 C 2 .   ? -15.998 -2.641  37.022  1   30.859 ? 601  V55 A CAF 1 
HETATM 8423 O  OAB . V55 C 2 .   ? -12.133 -0.093  38.172  1   31.575 ? 601  V55 A OAB 1 
HETATM 8424 C  CAE . V55 C 2 .   ? -15.365 -1.652  37.779  1   29.333 ? 601  V55 A CAE 1 
HETATM 8425 C  CAD . V55 C 2 .   ? -13.353 -0.279  38.296  1   32.871 ? 601  V55 A CAD 1 
HETATM 8426 C  CAA . V55 C 2 .   ? -12.14  -3.093  34.185  1   31.332 ? 601  V55 A CAA 1 
HETATM 8427 O  OAH . V55 C 2 .   ? -13.445 -3.511  34.582  1   35.286 ? 601  V55 A OAH 1 
HETATM 8428 O  OAC . V55 C 2 .   ? -15.965 -4.221  35.226  1   23.805 ? 601  V55 A OAC 1 
HETATM 8429 C  C1  . GOL D 3 .   ? -31.437 -20.226 46.925  1   75.929 ? 602  GOL A C1  1 
HETATM 8430 O  O1  . GOL D 3 .   ? -31.798 -18.884 47.256  1   65.748 ? 602  GOL A O1  1 
HETATM 8431 C  C2  . GOL D 3 .   ? -30.037 -20.236 46.355  1   61.221 ? 602  GOL A C2  1 
HETATM 8432 O  O2  . GOL D 3 .   ? -29.216 -19.552 47.287  1   66.138 ? 602  GOL A O2  1 
HETATM 8433 C  C3  . GOL D 3 .   ? -29.452 -21.592 46.024  1   70.95  ? 602  GOL A C3  1 
HETATM 8434 O  O3  . GOL D 3 .   ? -28.777 -21.56  44.77   1   62.742 ? 602  GOL A O3  1 
HETATM 8435 C  C1  . GOL E 3 .   ? -10.152 19.845  44.636  1   37.542 ? 603  GOL A C1  1 
HETATM 8436 O  O1  . GOL E 3 .   ? -11.413 19.177  44.635  1   31.404 ? 603  GOL A O1  1 
HETATM 8437 C  C2  . GOL E 3 .   ? -9.854  20.599  45.914  1   44.182 ? 603  GOL A C2  1 
HETATM 8438 O  O2  . GOL E 3 .   ? -10.459 19.99   47.059  1   41.399 ? 603  GOL A O2  1 
HETATM 8439 C  C3  . GOL E 3 .   ? -8.379  20.896  46.102  1   40.817 ? 603  GOL A C3  1 
HETATM 8440 O  O3  . GOL E 3 .   ? -7.881  20.425  47.35   1   46.573 ? 603  GOL A O3  1 
HETATM 8441 C  C1  . GOL F 3 .   ? -9.41   3.721   18.215  1   36.841 ? 604  GOL A C1  1 
HETATM 8442 O  O1  . GOL F 3 .   ? -9.532  4.056   19.605  1   29.643 ? 604  GOL A O1  1 
HETATM 8443 C  C2  . GOL F 3 .   ? -8.522  4.694   17.458  1   47.809 ? 604  GOL A C2  1 
HETATM 8444 O  O2  . GOL F 3 .   ? -8.328  4.296   16.104  1   54.297 ? 604  GOL A O2  1 
HETATM 8445 C  C3  . GOL F 3 .   ? -9.03   6.113   17.461  1   50.216 ? 604  GOL A C3  1 
HETATM 8446 O  O3  . GOL F 3 .   ? -8.598  6.782   18.639  1   62.971 ? 604  GOL A O3  1 
HETATM 8447 C  C1  . GOL G 3 .   ? 19.499  -6.95   28.404  1   47.451 ? 605  GOL A C1  1 
HETATM 8448 O  O1  . GOL G 3 .   ? 18.443  -6.31   27.691  1   30.127 ? 605  GOL A O1  1 
HETATM 8449 C  C2  . GOL G 3 .   ? 19.831  -6.324  29.747  1   50.322 ? 605  GOL A C2  1 
HETATM 8450 O  O2  . GOL G 3 .   ? 21.222  -5.993  29.87   1   49.699 ? 605  GOL A O2  1 
HETATM 8451 C  C3  . GOL G 3 .   ? 18.994  -5.134  30.108  1   45.737 ? 605  GOL A C3  1 
HETATM 8452 O  O3  . GOL G 3 .   ? 19.344  -3.994  29.334  1   28.811 ? 605  GOL A O3  1 
HETATM 8453 C  C1  . GOL H 3 .   ? -16.358 15.095  53.35   1   54.229 ? 606  GOL A C1  1 
HETATM 8454 O  O1  . GOL H 3 .   ? -17.695 15.051  53.841  1   61.313 ? 606  GOL A O1  1 
HETATM 8455 C  C2  . GOL H 3 .   ? -15.594 13.818  53.652  1   59.933 ? 606  GOL A C2  1 
HETATM 8456 O  O2  . GOL H 3 .   ? -14.421 13.75   52.848  1   50.283 ? 606  GOL A O2  1 
HETATM 8457 C  C3  . GOL H 3 .   ? -15.212 13.629  55.105  1   53.369 ? 606  GOL A C3  1 
HETATM 8458 O  O3  . GOL H 3 .   ? -16.361 13.431  55.917  1   61.638 ? 606  GOL A O3  1 
HETATM 8459 FE FE  . FE2 I 4 .   ? -10.884 -2.64   40.856  1   22.226 ? 607  FE2 A FE  1 
HETATM 8460 C  CAI . V55 J 2 .   ? 24.253  -6.699  3.145   1   38.867 ? 601  V55 B CAI 1 
HETATM 8461 C  CAG . V55 J 2 .   ? 23.488  -7.09   4.256   1   36.501 ? 601  V55 B CAG 1 
HETATM 8462 C  CAK . V55 J 2 .   ? 23.913  -8.123  5.079   1   30.262 ? 601  V55 B CAK 1 
HETATM 8463 C  CAJ . V55 J 2 .   ? 25.091  -8.838  4.755   1   31.509 ? 601  V55 B CAJ 1 
HETATM 8464 C  CAF . V55 J 2 .   ? 25.821  -8.485  3.628   1   30.811 ? 601  V55 B CAF 1 
HETATM 8465 O  OAB . V55 J 2 .   ? 22.634  -5.082  2.346   1   34.441 ? 601  V55 B OAB 1 
HETATM 8466 C  CAE . V55 J 2 .   ? 25.419  -7.399  2.858   1   33.403 ? 601  V55 B CAE 1 
HETATM 8467 C  CAD . V55 J 2 .   ? 23.775  -5.59   2.301   1   40.024 ? 601  V55 B CAD 1 
HETATM 8468 C  CAA . V55 J 2 .   ? 22.106  -7.816  6.673   1   35.933 ? 601  V55 B CAA 1 
HETATM 8469 O  OAH . V55 J 2 .   ? 23.25   -8.554  6.207   1   36.703 ? 601  V55 B OAH 1 
HETATM 8470 O  OAC . V55 J 2 .   ? 25.492  -9.904  5.499   1   25.3   ? 601  V55 B OAC 1 
HETATM 8471 C  C1  . GOL K 3 .   ? -8.769  -2.664  10.778  1   34.498 ? 602  GOL B C1  1 
HETATM 8472 O  O1  . GOL K 3 .   ? -8.678  -1.36   11.309  1   25.744 ? 602  GOL B O1  1 
HETATM 8473 C  C2  . GOL K 3 .   ? -9.122  -3.666  11.842  1   39.178 ? 602  GOL B C2  1 
HETATM 8474 O  O2  . GOL K 3 .   ? -9.108  -4.924  11.18   1   57.069 ? 602  GOL B O2  1 
HETATM 8475 C  C3  . GOL K 3 .   ? -8.326  -3.632  13.138  1   25.647 ? 602  GOL B C3  1 
HETATM 8476 O  O3  . GOL K 3 .   ? -8.595  -4.749  13.96   1   54.2   ? 602  GOL B O3  1 
HETATM 8477 FE FE  . FE2 L 4 .   ? 20.855  -7.487  -0.181  1   22.997 ? 603  FE2 B FE  1 
HETATM 8478 O  O   . HOH M 5 .   ? -6.118  17.035  37.225  1   29.28  ? 701  HOH A O   1 
HETATM 8479 O  O   . HOH M 5 .   ? 18.139  -31.745 18.088  1   35.542 ? 702  HOH A O   1 
HETATM 8480 O  O   . HOH M 5 .   ? -22.07  -15.404 41.873  1   37.424 ? 703  HOH A O   1 
HETATM 8481 O  O   . HOH M 5 .   ? -10.997 -2.057  38.942  1   31.93  ? 704  HOH A O   1 
HETATM 8482 O  O   . HOH M 5 .   ? 17.973  6.754   46.829  1   46.457 ? 705  HOH A O   1 
HETATM 8483 O  O   . HOH M 5 .   ? -10.742 7.704   61.79   1   33.441 ? 706  HOH A O   1 
HETATM 8484 O  O   . HOH M 5 .   ? 39.496  -23.599 17.62   1   44.075 ? 707  HOH A O   1 
HETATM 8485 O  O   . HOH M 5 .   ? -23.959 -0.745  30.422  1   20.961 ? 708  HOH A O   1 
HETATM 8486 O  O   . HOH M 5 .   ? -6.242  -6.375  56.007  1   35.495 ? 709  HOH A O   1 
HETATM 8487 O  O   . HOH M 5 .   ? -32.2   6.112   31.518  1   49.76  ? 710  HOH A O   1 
HETATM 8488 O  O   . HOH M 5 .   ? 11.896  6.352   51.645  1   35.346 ? 711  HOH A O   1 
HETATM 8489 O  O   . HOH M 5 .   ? 10.48   11.594  38.903  1   37.987 ? 712  HOH A O   1 
HETATM 8490 O  O   . HOH M 5 .   ? -21.463 15.110  59.280  1   45.234 ? 713  HOH A O   1 
HETATM 8491 O  O   . HOH M 5 .   ? -8.51   -22.678 55.415  1   33.28  ? 714  HOH A O   1 
HETATM 8492 O  O   . HOH M 5 .   ? -9.119  -24.292 34.718  1   29.032 ? 715  HOH A O   1 
HETATM 8493 O  O   . HOH M 5 .   ? -18.139 12.967  36.831  1   31.201 ? 716  HOH A O   1 
HETATM 8494 O  O   . HOH M 5 .   ? 16.952  -3.6    55.369  1   50.212 ? 717  HOH A O   1 
HETATM 8495 O  O   . HOH M 5 .   ? -7.721  -2.185  21.809  1   21.502 ? 718  HOH A O   1 
HETATM 8496 O  O   . HOH M 5 .   ? 13.881  -12.096 47.725  1   46.294 ? 719  HOH A O   1 
HETATM 8497 O  O   . HOH M 5 .   ? -8.593  20.522  49.812  1   30.91  ? 720  HOH A O   1 
HETATM 8498 O  O   . HOH M 5 .   ? -23.14  -5.412  64.431  1   36.076 ? 721  HOH A O   1 
HETATM 8499 O  O   . HOH M 5 .   ? -7.528  -6.716  63.189  1   29.176 ? 722  HOH A O   1 
HETATM 8500 O  O   . HOH M 5 .   ? -23.7   -8.77   33.541  1   23.731 ? 723  HOH A O   1 
HETATM 8501 O  O   . HOH M 5 .   ? -15.1   -6.591  41.402  1   21.82  ? 724  HOH A O   1 
HETATM 8502 O  O   . HOH M 5 .   ? -16.206 -25.388 56.773  1   24.466 ? 725  HOH A O   1 
HETATM 8503 O  O   . HOH M 5 .   ? -8.122  -9.214  44.58   1   26.971 ? 726  HOH A O   1 
HETATM 8504 O  O   . HOH M 5 .   ? -22.847 -13.252 63.666  1   46.683 ? 727  HOH A O   1 
HETATM 8505 O  O   . HOH M 5 .   ? -3.378  3.825   26.882  1   29.951 ? 728  HOH A O   1 
HETATM 8506 O  O   . HOH M 5 .   ? -7.698  2.184   12.118  1   32.683 ? 729  HOH A O   1 
HETATM 8507 O  O   . HOH M 5 .   ? -20.724 13.796  39.835  1   25.978 ? 730  HOH A O   1 
HETATM 8508 O  O   . HOH M 5 .   ? -7.487  -26.624 29.65   1   34.988 ? 731  HOH A O   1 
HETATM 8509 O  O   . HOH M 5 .   ? -5.556  -21.206 21.524  1   41.876 ? 732  HOH A O   1 
HETATM 8510 O  O   . HOH M 5 .   ? 14.613  3.893   45.591  1   25.353 ? 733  HOH A O   1 
HETATM 8511 O  O   . HOH M 5 .   ? -32.65  -12.23  56.914  1   48.655 ? 734  HOH A O   1 
HETATM 8512 O  O   . HOH M 5 .   ? 10.86   -18.662 36.177  1   27.868 ? 735  HOH A O   1 
HETATM 8513 O  O   . HOH M 5 .   ? 7.761   -21.942 30.021  1   48.167 ? 736  HOH A O   1 
HETATM 8514 O  O   . HOH M 5 .   ? 1.266   -0.446  37.432  1   19.414 ? 737  HOH A O   1 
HETATM 8515 O  O   . HOH M 5 .   ? -13.949 -20.375 40.181  1   22.743 ? 738  HOH A O   1 
HETATM 8516 O  O   . HOH M 5 .   ? 4.982   0.08    57.189  1   36.834 ? 739  HOH A O   1 
HETATM 8517 O  O   . HOH M 5 .   ? -6.338  18.42   46.775  1   39.998 ? 740  HOH A O   1 
HETATM 8518 O  O   . HOH M 5 .   ? -5.882  -17.188 21.723  1   29.02  ? 741  HOH A O   1 
HETATM 8519 O  O   . HOH M 5 .   ? -31.003 -0.193  20.602  1   51.088 ? 742  HOH A O   1 
HETATM 8520 O  O   . HOH M 5 .   ? -34.014 2.772   43.972  1   41.674 ? 743  HOH A O   1 
HETATM 8521 O  O   . HOH M 5 .   ? 42.441  -21.051 11.871  1   26.473 ? 744  HOH A O   1 
HETATM 8522 O  O   . HOH M 5 .   ? -28.878 -17.859 52.984  1   29.481 ? 745  HOH A O   1 
HETATM 8523 O  O   . HOH M 5 .   ? 10.315  -20.65  44.008  1   45.612 ? 746  HOH A O   1 
HETATM 8524 O  O   . HOH M 5 .   ? 15.571  -1.448  54.839  1   49.891 ? 747  HOH A O   1 
HETATM 8525 O  O   . HOH M 5 .   ? -11.615 7.085   32.588  1   42.985 ? 748  HOH A O   1 
HETATM 8526 O  O   . HOH M 5 .   ? -10.032 0.484   9.987   1   34.738 ? 749  HOH A O   1 
HETATM 8527 O  O   . HOH M 5 .   ? -9.604  9.636   45.369  1   23.447 ? 750  HOH A O   1 
HETATM 8528 O  O   . HOH M 5 .   ? 15.543  -11.318 49.607  1   46.09  ? 751  HOH A O   1 
HETATM 8529 O  O   . HOH M 5 .   ? 11.758  -8.28   46.76   1   25.541 ? 752  HOH A O   1 
HETATM 8530 O  O   . HOH M 5 .   ? 18.755  -8.042  50.679  1   42.661 ? 753  HOH A O   1 
HETATM 8531 O  O   . HOH M 5 .   ? -32.126 -11.559 51.972  1   49.263 ? 754  HOH A O   1 
HETATM 8532 O  O   . HOH M 5 .   ? -15.05  -12.894 34.796  1   20.65  ? 755  HOH A O   1 
HETATM 8533 O  O   . HOH M 5 .   ? -32.713 11.548  31.233  1   51.887 ? 756  HOH A O   1 
HETATM 8534 O  O   . HOH M 5 .   ? -17.44  -6.11   20.927  1   22.821 ? 757  HOH A O   1 
HETATM 8535 O  O   . HOH M 5 .   ? 18.325  -4.552  49.414  1   37.647 ? 758  HOH A O   1 
HETATM 8536 O  O   . HOH M 5 .   ? 12.328  -17.256 30.166  1   30.533 ? 759  HOH A O   1 
HETATM 8537 O  O   . HOH M 5 .   ? 8.834   7.348   36.456  1   25.632 ? 760  HOH A O   1 
HETATM 8538 O  O   . HOH M 5 .   ? -4.569  2.605   54.263  1   25.04  ? 761  HOH A O   1 
HETATM 8539 O  O   . HOH M 5 .   ? -2.582  2.383   56.174  1   32.937 ? 762  HOH A O   1 
HETATM 8540 O  O   . HOH M 5 .   ? -5.194  19.708  51.94   1   44.197 ? 763  HOH A O   1 
HETATM 8541 O  O   . HOH M 5 .   ? -18.433 -4.416  23.074  1   24.297 ? 764  HOH A O   1 
HETATM 8542 O  O   . HOH M 5 .   ? 7.052   13.097  52.093  1   48.527 ? 765  HOH A O   1 
HETATM 8543 O  O   . HOH M 5 .   ? 16.471  -7.997  31.711  1   22.165 ? 766  HOH A O   1 
HETATM 8544 O  O   . HOH M 5 .   ? -32.476 -2.672  42.537  1   28.84  ? 767  HOH A O   1 
HETATM 8545 O  O   . HOH M 5 .   ? -15.163 -7.029  65.654  1   31.107 ? 768  HOH A O   1 
HETATM 8546 O  O   . HOH M 5 .   ? -3.346  -19.325 50.118  1   31.157 ? 769  HOH A O   1 
HETATM 8547 O  O   . HOH M 5 .   ? -7.77   22.378  36.387  1   40.633 ? 770  HOH A O   1 
HETATM 8548 O  O   . HOH M 5 .   ? -19.729 15.223  37.825  1   29.567 ? 771  HOH A O   1 
HETATM 8549 O  O   . HOH M 5 .   ? -2.691  15.097  36.959  1   38.548 ? 772  HOH A O   1 
HETATM 8550 O  O   . HOH M 5 .   ? -4.881  -15.358 23.354  1   26.977 ? 773  HOH A O   1 
HETATM 8551 O  O   . HOH M 5 .   ? 27.561  -26.856 14.385  1   39.977 ? 774  HOH A O   1 
HETATM 8552 O  O   . HOH M 5 .   ? -19.606 -4.818  26.542  1   21.396 ? 775  HOH A O   1 
HETATM 8553 O  O   . HOH M 5 .   ? 8.954   4.397   51.843  1   32.017 ? 776  HOH A O   1 
HETATM 8554 O  O   . HOH M 5 .   ? 1.713   -13.004 56.024  1   37.289 ? 777  HOH A O   1 
HETATM 8555 O  O   . HOH M 5 .   ? -2.567  11.78   56.73   1   46.054 ? 778  HOH A O   1 
HETATM 8556 O  O   . HOH M 5 .   ? -30.477 -17.813 24.073  1   41.775 ? 779  HOH A O   1 
HETATM 8557 O  O   . HOH M 5 .   ? 41.742  -28.625 8.116   1   44.012 ? 780  HOH A O   1 
HETATM 8558 O  O   . HOH M 5 .   ? 0.609   -23.579 28.085  1   29.728 ? 781  HOH A O   1 
HETATM 8559 O  O   . HOH M 5 .   ? -25.516 -3.609  64.73   1   48.236 ? 782  HOH A O   1 
HETATM 8560 O  O   . HOH M 5 .   ? -20.105 -18.72  27.346  1   21.225 ? 783  HOH A O   1 
HETATM 8561 O  O   . HOH M 5 .   ? 29.234  -29.493 5.239   1   30.909 ? 784  HOH A O   1 
HETATM 8562 O  O   . HOH M 5 .   ? 5.854   -24.081 27.463  1   46.334 ? 785  HOH A O   1 
HETATM 8563 O  O   . HOH M 5 .   ? -0.606  13.654  10.196  1   33.884 ? 786  HOH A O   1 
HETATM 8564 O  O   . HOH M 5 .   ? 28.176  -21.761 7.598   1   30.211 ? 787  HOH A O   1 
HETATM 8565 O  O   . HOH M 5 .   ? 7.9     10.859  29.237  1   34.585 ? 788  HOH A O   1 
HETATM 8566 O  O   . HOH M 5 .   ? -19.517 -1.623  24.792  1   31.149 ? 789  HOH A O   1 
HETATM 8567 O  O   . HOH M 5 .   ? -35.01  -11.985 29.033  1   25.711 ? 790  HOH A O   1 
HETATM 8568 O  O   . HOH M 5 .   ? -12.599 -8.812  20.535  1   28.287 ? 791  HOH A O   1 
HETATM 8569 O  O   . HOH M 5 .   ? -8.697  -4.336  50.235  1   22.858 ? 792  HOH A O   1 
HETATM 8570 O  O   . HOH M 5 .   ? 1.07    1.68    29.797  1   27.816 ? 793  HOH A O   1 
HETATM 8571 O  O   . HOH M 5 .   ? -15.798 -5.567  14.568  1   23.858 ? 794  HOH A O   1 
HETATM 8572 O  O   . HOH M 5 .   ? 0.508   -3.041  54.411  1   24.387 ? 795  HOH A O   1 
HETATM 8573 O  O   . HOH M 5 .   ? 29.251  -33.048 8.101   1   53.326 ? 796  HOH A O   1 
HETATM 8574 O  O   . HOH M 5 .   ? -16.578 -14.551 28.331  1   20.304 ? 797  HOH A O   1 
HETATM 8575 O  O   . HOH M 5 .   ? -9.695  -11.194 26.467  1   18.819 ? 798  HOH A O   1 
HETATM 8576 O  O   . HOH M 5 .   ? -0.779  -22.356 37.819  1   25.963 ? 799  HOH A O   1 
HETATM 8577 O  O   . HOH M 5 .   ? -22.053 5.993   27.967  1   25.079 ? 800  HOH A O   1 
HETATM 8578 O  O   . HOH M 5 .   ? -6.002  -1.022  43.932  1   22.148 ? 801  HOH A O   1 
HETATM 8579 O  O   . HOH M 5 .   ? 4.29    1.087   59.429  1   36.318 ? 802  HOH A O   1 
HETATM 8580 O  O   . HOH M 5 .   ? -3.278  -2.593  17.597  1   20.025 ? 803  HOH A O   1 
HETATM 8581 O  O   . HOH M 5 .   ? 9.896   11.414  42.85   1   29.935 ? 804  HOH A O   1 
HETATM 8582 O  O   . HOH M 5 .   ? -24.228 2.775   62.862  1   32.728 ? 805  HOH A O   1 
HETATM 8583 O  O   . HOH M 5 .   ? -10.221 10.033  26.161  1   36.372 ? 806  HOH A O   1 
HETATM 8584 O  O   . HOH M 5 .   ? -17.625 -7.913  65.832  1   33.378 ? 807  HOH A O   1 
HETATM 8585 O  O   . HOH M 5 .   ? -3.96   17.668  45.363  1   46.44  ? 808  HOH A O   1 
HETATM 8586 O  O   . HOH M 5 .   ? 19.246  -1.711  42.457  1   34.12  ? 809  HOH A O   1 
HETATM 8587 O  O   . HOH M 5 .   ? -5.223  -5.795  56.034  1   34.284 ? 810  HOH A O   1 
HETATM 8588 O  O   . HOH M 5 .   ? -17.479 -7.566  42.635  1   19.532 ? 811  HOH A O   1 
HETATM 8589 O  O   . HOH M 5 .   ? 15.213  -7.883  54.259  1   37.983 ? 812  HOH A O   1 
HETATM 8590 O  O   . HOH M 5 .   ? -4.771  -16.967 26.937  1   19.538 ? 813  HOH A O   1 
HETATM 8591 O  O   . HOH M 5 .   ? -20.765 -13.091 32.189  1   25.72  ? 814  HOH A O   1 
HETATM 8592 O  O   . HOH M 5 .   ? -17.609 5.371   23.938  1   29.808 ? 815  HOH A O   1 
HETATM 8593 O  O   . HOH M 5 .   ? -30.211 7.375   38.246  1   26.574 ? 816  HOH A O   1 
HETATM 8594 O  O   . HOH M 5 .   ? -30.132 -5.041  20.875  1   42.375 ? 817  HOH A O   1 
HETATM 8595 O  O   . HOH M 5 .   ? -1.832  5.515   32.825  1   22.031 ? 818  HOH A O   1 
HETATM 8596 O  O   . HOH M 5 .   ? -7.803  -12.605 58.665  1   24.452 ? 819  HOH A O   1 
HETATM 8597 O  O   . HOH M 5 .   ? -4.996  11.346  30.844  1   41.273 ? 820  HOH A O   1 
HETATM 8598 O  O   . HOH M 5 .   ? -23.098 13.418  46.023  1   39.292 ? 821  HOH A O   1 
HETATM 8599 O  O   . HOH M 5 .   ? 10.11   11.965  27.933  1   46.451 ? 822  HOH A O   1 
HETATM 8600 O  O   . HOH M 5 .   ? 11.954  9.12    38.3    1   33.527 ? 823  HOH A O   1 
HETATM 8601 O  O   . HOH M 5 .   ? -6.365  -22.298 25.455  1   30.772 ? 824  HOH A O   1 
HETATM 8602 O  O   . HOH M 5 .   ? 12.269  -20.861 30.146  1   51.372 ? 825  HOH A O   1 
HETATM 8603 O  O   . HOH M 5 .   ? -13.672 20.533  45.168  1   32.053 ? 826  HOH A O   1 
HETATM 8604 O  O   . HOH M 5 .   ? 10.909  -15.586 32.712  1   22.168 ? 827  HOH A O   1 
HETATM 8605 O  O   . HOH M 5 .   ? 15.885  -10.173 40.321  1   29.35  ? 828  HOH A O   1 
HETATM 8606 O  O   . HOH M 5 .   ? 10.953  -22.505 30.215  1   40.362 ? 829  HOH A O   1 
HETATM 8607 O  O   . HOH M 5 .   ? 3.399   -24.686 35.968  1   30.184 ? 830  HOH A O   1 
HETATM 8608 O  O   . HOH M 5 .   ? -29.277 -14.957 47.738  1   25.44  ? 831  HOH A O   1 
HETATM 8609 O  O   . HOH M 5 .   ? 15.773  -11.151 23.484  1   22.41  ? 832  HOH A O   1 
HETATM 8610 O  O   . HOH M 5 .   ? -17.417 -16.854 16.221  1   23.842 ? 833  HOH A O   1 
HETATM 8611 O  O   . HOH M 5 .   ? -33.697 0.446   45.057  1   49.692 ? 834  HOH A O   1 
HETATM 8612 O  O   . HOH M 5 .   ? -2.827  2.168   24.543  1   27.037 ? 835  HOH A O   1 
HETATM 8613 O  O   . HOH M 5 .   ? -14.925 -25.615 45.247  1   43.551 ? 836  HOH A O   1 
HETATM 8614 O  O   . HOH M 5 .   ? -17.101 3.624   67.715  1   36.511 ? 837  HOH A O   1 
HETATM 8615 O  O   . HOH M 5 .   ? -0.983  -7.228  61.966  1   41.037 ? 838  HOH A O   1 
HETATM 8616 O  O   . HOH M 5 .   ? -5.681  3.005   33.577  1   22.525 ? 839  HOH A O   1 
HETATM 8617 O  O   . HOH M 5 .   ? 1.163   -4.762  46.848  1   24.161 ? 840  HOH A O   1 
HETATM 8618 O  O   . HOH M 5 .   ? -14.159 4.165   25.231  1   23.011 ? 841  HOH A O   1 
HETATM 8619 O  O   . HOH M 5 .   ? -9.112  16.49   47.182  1   33.535 ? 842  HOH A O   1 
HETATM 8620 O  O   . HOH M 5 .   ? -4.023  -9.474  18.529  1   22.857 ? 843  HOH A O   1 
HETATM 8621 O  O   . HOH M 5 .   ? -17.184 -1.235  45.576  1   22.083 ? 844  HOH A O   1 
HETATM 8622 O  O   . HOH M 5 .   ? -38.252 -6.446  32.669  1   39.002 ? 845  HOH A O   1 
HETATM 8623 O  O   . HOH M 5 .   ? -27.976 2.905   24.358  1   35.075 ? 846  HOH A O   1 
HETATM 8624 O  O   . HOH M 5 .   ? -4.372  -25.93  36.702  1   44.454 ? 847  HOH A O   1 
HETATM 8625 O  O   . HOH M 5 .   ? 15.926  -21.77  39.336  1   46.109 ? 848  HOH A O   1 
HETATM 8626 O  O   . HOH M 5 .   ? -32.843 -6.986  49.035  1   36.472 ? 849  HOH A O   1 
HETATM 8627 O  O   . HOH M 5 .   ? -3.067  -21.643 36.534  1   21.554 ? 850  HOH A O   1 
HETATM 8628 O  O   . HOH M 5 .   ? -2.843  -8.337  23.991  1   23.264 ? 851  HOH A O   1 
HETATM 8629 O  O   . HOH M 5 .   ? -31.883 -21.158 25.747  1   49.763 ? 852  HOH A O   1 
HETATM 8630 O  O   . HOH M 5 .   ? -25.205 2.519   59.183  1   27.956 ? 853  HOH A O   1 
HETATM 8631 O  O   . HOH M 5 .   ? -35.612 14.826  36.193  1   49.857 ? 854  HOH A O   1 
HETATM 8632 O  O   . HOH M 5 .   ? -12.697 0.821   25.081  1   22.815 ? 855  HOH A O   1 
HETATM 8633 O  O   . HOH M 5 .   ? 21.652  -9.047  29.424  1   30.281 ? 856  HOH A O   1 
HETATM 8634 O  O   . HOH M 5 .   ? -14.606 -6.402  37.525  1   20.649 ? 857  HOH A O   1 
HETATM 8635 O  O   . HOH M 5 .   ? 20.478  1.527   40.125  1   42.436 ? 858  HOH A O   1 
HETATM 8636 O  O   . HOH M 5 .   ? -5.155  8.14    22.663  1   34.428 ? 859  HOH A O   1 
HETATM 8637 O  O   . HOH M 5 .   ? -10.251 16.195  41.472  1   33.373 ? 860  HOH A O   1 
HETATM 8638 O  O   . HOH M 5 .   ? 9.479   0.968   54.886  1   39.872 ? 861  HOH A O   1 
HETATM 8639 O  O   . HOH M 5 .   ? -20.475 -6.758  28.841  1   23.269 ? 862  HOH A O   1 
HETATM 8640 O  O   . HOH M 5 .   ? 2.394   -10.248 46.933  1   30.434 ? 863  HOH A O   1 
HETATM 8641 O  O   . HOH M 5 .   ? -24.433 -12.71  27.861  1   27.114 ? 864  HOH A O   1 
HETATM 8642 O  O   . HOH M 5 .   ? -14.449 -17.581 39.905  1   21.76  ? 865  HOH A O   1 
HETATM 8643 O  O   . HOH M 5 .   ? -8.723  -3.261  46.723  1   21.127 ? 866  HOH A O   1 
HETATM 8644 O  O   . HOH M 5 .   ? 5.633   -15.413 39.971  1   23.311 ? 867  HOH A O   1 
HETATM 8645 O  O   . HOH M 5 .   ? -24.276 -4.534  14.097  1   36.704 ? 868  HOH A O   1 
HETATM 8646 O  O   . HOH M 5 .   ? -20.524 0.032   27.447  1   23.881 ? 869  HOH A O   1 
HETATM 8647 O  O   . HOH M 5 .   ? -17.114 -5.718  28.8    1   22.287 ? 870  HOH A O   1 
HETATM 8648 O  O   . HOH M 5 .   ? -25.197 -12.374 36.63   1   21.287 ? 871  HOH A O   1 
HETATM 8649 O  O   . HOH M 5 .   ? -21.723 -8.986  39.206  1   22.028 ? 872  HOH A O   1 
HETATM 8650 O  O   . HOH M 5 .   ? -15.59  -25.391 36.265  1   38.486 ? 873  HOH A O   1 
HETATM 8651 O  O   . HOH M 5 .   ? 17.055  -17.885 40.842  1   46.463 ? 874  HOH A O   1 
HETATM 8652 O  O   . HOH M 5 .   ? -1.294  -12.679 48.81   1   35.409 ? 875  HOH A O   1 
HETATM 8653 O  O   . HOH M 5 .   ? -22.966 -13.236 35.155  1   22.849 ? 876  HOH A O   1 
HETATM 8654 O  O   . HOH M 5 .   ? -2.81   9.624   58.959  1   42.516 ? 877  HOH A O   1 
HETATM 8655 O  O   . HOH M 5 .   ? 3.915   -8.602  50.528  1   33.155 ? 878  HOH A O   1 
HETATM 8656 O  O   . HOH M 5 .   ? -29.134 7.959   31.327  1   40.904 ? 879  HOH A O   1 
HETATM 8657 O  O   . HOH M 5 .   ? 8.908   12.97   45.191  1   39.57  ? 880  HOH A O   1 
HETATM 8658 O  O   . HOH M 5 .   ? -9.367  2.682   65.607  1   45.23  ? 881  HOH A O   1 
HETATM 8659 O  O   . HOH M 5 .   ? -32.281 -11.506 34.699  1   25.863 ? 882  HOH A O   1 
HETATM 8660 O  O   . HOH M 5 .   ? 5.723   7.011   54.713  1   28.229 ? 883  HOH A O   1 
HETATM 8661 O  O   . HOH M 5 .   ? -20.604 -2.911  20.427  1   19.221 ? 884  HOH A O   1 
HETATM 8662 O  O   . HOH M 5 .   ? -26.288 5.162   32.849  1   22.63  ? 885  HOH A O   1 
HETATM 8663 O  O   . HOH M 5 .   ? 10.302  -10.898 45.29   1   27.454 ? 886  HOH A O   1 
HETATM 8664 O  O   . HOH M 5 .   ? -8.324  -6.761  45.703  1   24.503 ? 887  HOH A O   1 
HETATM 8665 O  O   . HOH M 5 .   ? 20.269  -5.31   36.766  1   34.87  ? 888  HOH A O   1 
HETATM 8666 O  O   . HOH M 5 .   ? 44.794  -20.759 5.514   1   36.554 ? 889  HOH A O   1 
HETATM 8667 O  O   . HOH M 5 .   ? 4.795   18.12   44.975  1   64.494 ? 890  HOH A O   1 
HETATM 8668 O  O   . HOH M 5 .   ? -8.554  -22.235 22.399  1   31.586 ? 891  HOH A O   1 
HETATM 8669 O  O   . HOH M 5 .   ? 15.692  -13.563 41.778  1   27.457 ? 892  HOH A O   1 
HETATM 8670 O  O   . HOH M 5 .   ? -20.352 -19.221 55.949  1   27.573 ? 893  HOH A O   1 
HETATM 8671 O  O   . HOH M 5 .   ? -23.988 3.332   47.405  1   40.481 ? 894  HOH A O   1 
HETATM 8672 O  O   . HOH M 5 .   ? 23.109  -24.118 21.752  1   26.121 ? 895  HOH A O   1 
HETATM 8673 O  O   . HOH M 5 .   ? 14.669  -5.928  55.66   1   37.306 ? 896  HOH A O   1 
HETATM 8674 O  O   . HOH M 5 .   ? -0.537  -1.822  32.402  1   24.716 ? 897  HOH A O   1 
HETATM 8675 O  O   . HOH M 5 .   ? 20.507  -2.429  33.396  1   42.643 ? 898  HOH A O   1 
HETATM 8676 O  O   . HOH M 5 .   ? -12.011 -0.866  27.125  1   21.113 ? 899  HOH A O   1 
HETATM 8677 O  O   . HOH M 5 .   ? -4.017  8.455   35.116  1   23.672 ? 900  HOH A O   1 
HETATM 8678 O  O   . HOH M 5 .   ? -21.781 1.227   21.733  1   23.696 ? 901  HOH A O   1 
HETATM 8679 O  O   . HOH M 5 .   ? 13.287  -18.903 22.722  1   23.067 ? 902  HOH A O   1 
HETATM 8680 O  O   . HOH M 5 .   ? -2.172  -23.133 48.351  1   43.247 ? 903  HOH A O   1 
HETATM 8681 O  O   . HOH M 5 .   ? 0.476   -3.48   60.826  1   30.259 ? 904  HOH A O   1 
HETATM 8682 O  O   . HOH M 5 .   ? -37.834 -2.17   28.293  1   38.192 ? 905  HOH A O   1 
HETATM 8683 O  O   . HOH M 5 .   ? 6.782   -4.853  60.404  1   37.607 ? 906  HOH A O   1 
HETATM 8684 O  O   . HOH M 5 .   ? -12.429 -10.907 26.452  1   19.514 ? 907  HOH A O   1 
HETATM 8685 O  O   . HOH M 5 .   ? 17.96   -28.776 24.483  1   33.958 ? 908  HOH A O   1 
HETATM 8686 O  O   . HOH M 5 .   ? -15.146 -7.916  23.306  1   20.476 ? 909  HOH A O   1 
HETATM 8687 O  O   . HOH M 5 .   ? -26.7   -18.327 62.359  1   42.395 ? 910  HOH A O   1 
HETATM 8688 O  O   . HOH M 5 .   ? -14.893 -6.052  19.882  1   23.694 ? 911  HOH A O   1 
HETATM 8689 O  O   . HOH M 5 .   ? -20.416 -4.017  37.107  1   21.987 ? 912  HOH A O   1 
HETATM 8690 O  O   . HOH M 5 .   ? -0.812  -25.692 31.639  1   38.121 ? 913  HOH A O   1 
HETATM 8691 O  O   . HOH M 5 .   ? -0.437  -2.973  39.345  1   20.684 ? 914  HOH A O   1 
HETATM 8692 O  O   . HOH M 5 .   ? -28.452 1.841   52.302  1   29.886 ? 915  HOH A O   1 
HETATM 8693 O  O   . HOH M 5 .   ? 18.236  -13.267 42.695  1   51.728 ? 916  HOH A O   1 
HETATM 8694 O  O   . HOH M 5 .   ? -2.931  -20.246 47.671  1   28.744 ? 917  HOH A O   1 
HETATM 8695 O  O   . HOH M 5 .   ? -21.513 15.06   44.289  1   39.536 ? 918  HOH A O   1 
HETATM 8696 O  O   . HOH M 5 .   ? -17.062 -14.681 62.214  1   47.046 ? 919  HOH A O   1 
HETATM 8697 O  O   . HOH M 5 .   ? -4.088  1.028   58.087  1   29.856 ? 920  HOH A O   1 
HETATM 8698 O  O   . HOH M 5 .   ? 16.632  -15.6   35.49   1   41.199 ? 921  HOH A O   1 
HETATM 8699 O  O   . HOH M 5 .   ? -20.326 9.335   19.065  1   57.131 ? 922  HOH A O   1 
HETATM 8700 O  O   . HOH M 5 .   ? -25.252 -9.84   35.668  1   19.961 ? 923  HOH A O   1 
HETATM 8701 O  O   . HOH M 5 .   ? -19.431 -25.906 38.234  1   54.177 ? 924  HOH A O   1 
HETATM 8702 O  O   . HOH M 5 .   ? 3.494   14.299  52.898  1   47.516 ? 925  HOH A O   1 
HETATM 8703 O  O   . HOH M 5 .   ? -12.518 13.138  40.811  1   24.484 ? 926  HOH A O   1 
HETATM 8704 O  O   . HOH M 5 .   ? -5.728  -5.882  44.311  1   33.319 ? 927  HOH A O   1 
HETATM 8705 O  O   . HOH M 5 .   ? 16.045  7.222   39.073  1   35.604 ? 928  HOH A O   1 
HETATM 8706 O  O   . HOH M 5 .   ? -10.031 16.822  44.093  1   29.969 ? 929  HOH A O   1 
HETATM 8707 O  O   . HOH M 5 .   ? -36.181 12.924  34      1   42.062 ? 930  HOH A O   1 
HETATM 8708 O  O   . HOH M 5 .   ? -2.648  -11.481 50.648  1   34.404 ? 931  HOH A O   1 
HETATM 8709 O  O   . HOH M 5 .   ? -12.811 6.734   60.537  1   29.7   ? 932  HOH A O   1 
HETATM 8710 O  O   . HOH M 5 .   ? -2.397  6.138   35.402  1   23.022 ? 933  HOH A O   1 
HETATM 8711 O  O   . HOH M 5 .   ? -32.85  -3.793  40.089  1   46.34  ? 934  HOH A O   1 
HETATM 8712 O  O   . HOH M 5 .   ? -9.301  -10.894 18.131  1   18.975 ? 935  HOH A O   1 
HETATM 8713 O  O   . HOH M 5 .   ? 11.94   0.801   53.829  1   40.336 ? 936  HOH A O   1 
HETATM 8714 O  O   . HOH M 5 .   ? -30.339 -19.116 35.046  1   50.308 ? 937  HOH A O   1 
HETATM 8715 O  O   . HOH M 5 .   ? 28.914  -32.255 13.078  1   38.484 ? 938  HOH A O   1 
HETATM 8716 O  O   . HOH M 5 .   ? 8.111   -11.744 46.745  1   32.919 ? 939  HOH A O   1 
HETATM 8717 O  O   . HOH M 5 .   ? 10.435  6.086   34.23   1   33.638 ? 940  HOH A O   1 
HETATM 8718 O  O   . HOH M 5 .   ? -7.482  1.027   31.877  1   21.963 ? 941  HOH A O   1 
HETATM 8719 O  O   . HOH M 5 .   ? 0.255   -7.278  44.637  1   23.515 ? 942  HOH A O   1 
HETATM 8720 O  O   . HOH M 5 .   ? -19.149 3.144   63.336  1   27.979 ? 943  HOH A O   1 
HETATM 8721 O  O   . HOH M 5 .   ? 7.469   1.299   19.377  1   28.242 ? 944  HOH A O   1 
HETATM 8722 O  O   . HOH M 5 .   ? -15.157 12.576  36.707  1   30.318 ? 945  HOH A O   1 
HETATM 8723 O  O   . HOH M 5 .   ? -9.148  -5.979  52.38   1   21.748 ? 946  HOH A O   1 
HETATM 8724 O  O   . HOH M 5 .   ? -14.653 20.489  36.715  1   43.114 ? 947  HOH A O   1 
HETATM 8725 O  O   . HOH M 5 .   ? -28.79  8.011   61.589  1   46.781 ? 948  HOH A O   1 
HETATM 8726 O  O   . HOH M 5 .   ? -22.754 -8.272  60.505  1   26.163 ? 949  HOH A O   1 
HETATM 8727 O  O   . HOH M 5 .   ? -10.576 14.049  32.584  1   35.28  ? 950  HOH A O   1 
HETATM 8728 O  O   . HOH M 5 .   ? -18.227 18.932  42.597  1   40.58  ? 951  HOH A O   1 
HETATM 8729 O  O   . HOH M 5 .   ? -26.108 11.750  50.529  1   37.459 ? 952  HOH A O   1 
HETATM 8730 O  O   . HOH M 5 .   ? 14.792  -17.469 31.683  1   35.625 ? 953  HOH A O   1 
HETATM 8731 O  O   . HOH M 5 .   ? -9.878  13.82   40.145  1   25.226 ? 954  HOH A O   1 
HETATM 8732 O  O   . HOH M 5 .   ? -25.739 -5.799  44.425  1   22.602 ? 955  HOH A O   1 
HETATM 8733 O  O   . HOH M 5 .   ? -16.931 5.886   59.035  1   36.011 ? 956  HOH A O   1 
HETATM 8734 O  O   . HOH M 5 .   ? -33.309 -10.051 42.778  1   32.076 ? 957  HOH A O   1 
HETATM 8735 O  O   . HOH M 5 .   ? -17.638 -8.037  30.138  1   20.309 ? 958  HOH A O   1 
HETATM 8736 O  O   . HOH M 5 .   ? -14.293 14.761  35.329  1   38.306 ? 959  HOH A O   1 
HETATM 8737 O  O   . HOH M 5 .   ? -0.336  3.372   25.955  1   40.098 ? 960  HOH A O   1 
HETATM 8738 O  O   . HOH M 5 .   ? 18.158  -7.016  33.528  1   31.463 ? 961  HOH A O   1 
HETATM 8739 O  O   . HOH M 5 .   ? -2.558  19.864  44.101  1   41.306 ? 962  HOH A O   1 
HETATM 8740 O  O   . HOH M 5 .   ? -29.689 -10.928 52.777  1   31.191 ? 963  HOH A O   1 
HETATM 8741 O  O   . HOH M 5 .   ? -26.602 -8.357  43.604  1   21.93  ? 964  HOH A O   1 
HETATM 8742 O  O   . HOH M 5 .   ? 1.891   -14.592 24.543  1   19.976 ? 965  HOH A O   1 
HETATM 8743 O  O   . HOH M 5 .   ? 6.121   -18.027 23.138  1   46.688 ? 966  HOH A O   1 
HETATM 8744 O  O   . HOH M 5 .   ? -7.031  1.064   57.421  1   35.058 ? 967  HOH A O   1 
HETATM 8745 O  O   . HOH M 5 .   ? 0.592   -21.596 24.628  1   45.032 ? 968  HOH A O   1 
HETATM 8746 O  O   . HOH M 5 .   ? -9.68   -25.727 54.947  1   46.932 ? 969  HOH A O   1 
HETATM 8747 O  O   . HOH M 5 .   ? -20.772 -24.823 48.386  1   36.293 ? 970  HOH A O   1 
HETATM 8748 O  O   . HOH M 5 .   ? -17.994 -25.277 44.866  1   49.757 ? 971  HOH A O   1 
HETATM 8749 O  O   . HOH M 5 .   ? -17.767 -11.97  62.862  1   47.405 ? 972  HOH A O   1 
HETATM 8750 O  O   . HOH M 5 .   ? -15.321 7.785   61.247  1   29.958 ? 973  HOH A O   1 
HETATM 8751 O  O   . HOH M 5 .   ? -25.805 2.997   67.903  1   45.774 ? 974  HOH A O   1 
HETATM 8752 O  O   . HOH M 5 .   ? -5.725  -3.133  47.949  1   26.6   ? 975  HOH A O   1 
HETATM 8753 O  O   . HOH M 5 .   ? -9.558  19.635  53.135  1   26.15  ? 976  HOH A O   1 
HETATM 8754 O  O   . HOH M 5 .   ? -4.788  -19.277 25.353  1   31.021 ? 977  HOH A O   1 
HETATM 8755 O  O   . HOH M 5 .   ? -20.62  14.256  33.032  1   49.885 ? 978  HOH A O   1 
HETATM 8756 O  O   . HOH M 5 .   ? -28.646 4.2     29.099  1   28.869 ? 979  HOH A O   1 
HETATM 8757 O  O   . HOH M 5 .   ? -12.196 7.017   29.095  1   35.247 ? 980  HOH A O   1 
HETATM 8758 O  O   . HOH M 5 .   ? 20.597  -6.319  43.805  1   41.758 ? 981  HOH A O   1 
HETATM 8759 O  O   . HOH M 5 .   ? -23.627 -0.935  14.998  1   29.589 ? 982  HOH A O   1 
HETATM 8760 O  O   . HOH M 5 .   ? 13.16   -4.145  25.908  1   22.852 ? 983  HOH A O   1 
HETATM 8761 O  O   . HOH M 5 .   ? -26.751 -19.723 52.229  1   32.435 ? 984  HOH A O   1 
HETATM 8762 O  O   . HOH M 5 .   ? 19.099  -30.296 22.247  1   27.452 ? 985  HOH A O   1 
HETATM 8763 O  O   . HOH M 5 .   ? -11.465 -21.348 57.078  1   42.017 ? 986  HOH A O   1 
HETATM 8764 O  O   . HOH M 5 .   ? 8.046   -22.128 42.813  1   30.09  ? 987  HOH A O   1 
HETATM 8765 O  O   . HOH M 5 .   ? -26.859 -22.914 58.578  1   49.871 ? 988  HOH A O   1 
HETATM 8766 O  O   . HOH M 5 .   ? -13.661 -24.581 31.607  1   30.069 ? 989  HOH A O   1 
HETATM 8767 O  O   . HOH M 5 .   ? -26.833 -1.099  16.752  1   28.663 ? 990  HOH A O   1 
HETATM 8768 O  O   . HOH M 5 .   ? -29.002 -20.377 56.592  1   46.124 ? 991  HOH A O   1 
HETATM 8769 O  O   . HOH M 5 .   ? -5.67   -10.399 43.708  1   26.562 ? 992  HOH A O   1 
HETATM 8770 O  O   . HOH M 5 .   ? -6.093  4.783   35.57   1   22.796 ? 993  HOH A O   1 
HETATM 8771 O  O   . HOH M 5 .   ? -28.084 0.862   57.186  1   29.621 ? 994  HOH A O   1 
HETATM 8772 O  O   . HOH M 5 .   ? 3.072   14.154  35.13   1   31.334 ? 995  HOH A O   1 
HETATM 8773 O  O   . HOH M 5 .   ? -5.254  -10.421 48.583  1   25.48  ? 996  HOH A O   1 
HETATM 8774 O  O   . HOH M 5 .   ? -33.497 -9.511  37.753  1   28.313 ? 997  HOH A O   1 
HETATM 8775 O  O   . HOH M 5 .   ? -9.925  -1.428  25.127  1   24.066 ? 998  HOH A O   1 
HETATM 8776 O  O   . HOH M 5 .   ? -3.669  4.146   36.941  1   22.342 ? 999  HOH A O   1 
HETATM 8777 O  O   . HOH M 5 .   ? 3.526   -23.892 31.242  1   32.192 ? 1000 HOH A O   1 
HETATM 8778 O  O   . HOH M 5 .   ? -11.347 -15.319 12.155  1   35.911 ? 1001 HOH A O   1 
HETATM 8779 O  O   . HOH M 5 .   ? -31.975 9.562   38.234  1   38.715 ? 1002 HOH A O   1 
HETATM 8780 O  O   . HOH M 5 .   ? -0.54   -20.628 44.69   1   31.172 ? 1003 HOH A O   1 
HETATM 8781 O  O   . HOH M 5 .   ? -16.478 6.123   18.871  1   44.147 ? 1004 HOH A O   1 
HETATM 8782 O  O   . HOH M 5 .   ? -2.729  -5.169  48.102  1   29.454 ? 1005 HOH A O   1 
HETATM 8783 O  O   . HOH M 5 .   ? -13.77  -6.844  13.327  1   24.574 ? 1006 HOH A O   1 
HETATM 8784 O  O   . HOH M 5 .   ? -34.669 -4.369  37.408  1   29.626 ? 1007 HOH A O   1 
HETATM 8785 O  O   . HOH M 5 .   ? 19.527  -30.406 15.072  1   34.034 ? 1008 HOH A O   1 
HETATM 8786 O  O   . HOH M 5 .   ? 10.032  -27.521 33.855  1   50.641 ? 1009 HOH A O   1 
HETATM 8787 O  O   . HOH M 5 .   ? -11.493 -11.303 19.847  1   20.909 ? 1010 HOH A O   1 
HETATM 8788 O  O   . HOH M 5 .   ? -4.985  -7.811  63.442  1   31.227 ? 1011 HOH A O   1 
HETATM 8789 O  O   . HOH M 5 .   ? -3.245  15.232  52.692  1   31.566 ? 1012 HOH A O   1 
HETATM 8790 O  O   . HOH M 5 .   ? 29.077  -25.737 12.778  1   32.258 ? 1013 HOH A O   1 
HETATM 8791 O  O   . HOH M 5 .   ? 14.448  -29.994 16.765  1   34.11  ? 1014 HOH A O   1 
HETATM 8792 O  O   . HOH M 5 .   ? -23.072 -7.003  13.227  1   43.601 ? 1015 HOH A O   1 
HETATM 8793 O  O   . HOH M 5 .   ? -23.58  0.119   32.932  1   19.467 ? 1016 HOH A O   1 
HETATM 8794 O  O   . HOH M 5 .   ? 9.52    -16.082 45.936  1   34.677 ? 1017 HOH A O   1 
HETATM 8795 O  O   . HOH M 5 .   ? 2.39    -6.992  48.681  1   29.247 ? 1018 HOH A O   1 
HETATM 8796 O  O   . HOH M 5 .   ? -20.829 -24.239 39.331  1   53.849 ? 1019 HOH A O   1 
HETATM 8797 O  O   . HOH M 5 .   ? -11.054 14.197  58.526  1   32.469 ? 1020 HOH A O   1 
HETATM 8798 O  O   . HOH M 5 .   ? -1.683  -3.712  25.672  1   23.879 ? 1021 HOH A O   1 
HETATM 8799 O  O   . HOH M 5 .   ? -19.895 12.199  61.619  1   33.269 ? 1022 HOH A O   1 
HETATM 8800 O  O   . HOH M 5 .   ? 8.37    12.094  49.977  1   31.489 ? 1023 HOH A O   1 
HETATM 8801 O  O   . HOH M 5 .   ? 25.112  -29.782 19.033  1   33.235 ? 1024 HOH A O   1 
HETATM 8802 O  O   . HOH M 5 .   ? 9.365   -24.09  41.257  1   30.752 ? 1025 HOH A O   1 
HETATM 8803 O  O   . HOH M 5 .   ? -6.923  -15.736 10.223  1   52.362 ? 1026 HOH A O   1 
HETATM 8804 O  O   . HOH M 5 .   ? -1.072  -2.055  66.711  1   51.754 ? 1027 HOH A O   1 
HETATM 8805 O  O   . HOH M 5 .   ? -31.808 -11.85  31.783  1   23.311 ? 1028 HOH A O   1 
HETATM 8806 O  O   . HOH M 5 .   ? -11.831 9.694   28.313  1   41.94  ? 1029 HOH A O   1 
HETATM 8807 O  O   . HOH M 5 .   ? 9.097   19.255  30.777  1   45.955 ? 1030 HOH A O   1 
HETATM 8808 O  O   . HOH M 5 .   ? -21.651 -17.768 62.812  1   56.585 ? 1031 HOH A O   1 
HETATM 8809 O  O   . HOH M 5 .   ? 30.213  -32.196 10.427  1   32.698 ? 1032 HOH A O   1 
HETATM 8810 O  O   . HOH M 5 .   ? -11.146 7.967   10.08   1   42.755 ? 1033 HOH A O   1 
HETATM 8811 O  O   . HOH M 5 .   ? -6.047  -25.166 27.54   1   31.725 ? 1034 HOH A O   1 
HETATM 8812 O  O   . HOH M 5 .   ? 13.946  8.566   40.035  1   30.909 ? 1035 HOH A O   1 
HETATM 8813 O  O   . HOH M 5 .   ? -33.484 12.406  42.222  1   37.947 ? 1036 HOH A O   1 
HETATM 8814 O  O   . HOH M 5 .   ? -29.409 -17.941 55.551  1   30.64  ? 1037 HOH A O   1 
HETATM 8815 O  O   . HOH M 5 .   ? 6.295   -25.964 41.948  1   38.838 ? 1038 HOH A O   1 
HETATM 8816 O  O   . HOH M 5 .   ? 6.25    -19.929 28.61   1   40.058 ? 1039 HOH A O   1 
HETATM 8817 O  O   . HOH M 5 .   ? -1.339  21.349  47.667  1   51.782 ? 1040 HOH A O   1 
HETATM 8818 O  O   . HOH M 5 .   ? -14.181 -13.031 38.251  1   20.67  ? 1041 HOH A O   1 
HETATM 8819 O  O   . HOH M 5 .   ? -31.577 3.107   21.832  1   60.201 ? 1042 HOH A O   1 
HETATM 8820 O  O   . HOH M 5 .   ? -31.499 2.367   37.94   1   32.554 ? 1043 HOH A O   1 
HETATM 8821 O  O   . HOH M 5 .   ? -26.437 13.603  47.05   1   50.877 ? 1044 HOH A O   1 
HETATM 8822 O  O   . HOH M 5 .   ? 13.044  -23.309 28.864  1   39.988 ? 1045 HOH A O   1 
HETATM 8823 O  O   . HOH M 5 .   ? 8.175   -19.048 24.627  1   38.183 ? 1046 HOH A O   1 
HETATM 8824 O  O   . HOH M 5 .   ? -36.88  -3.337  35.576  1   34.212 ? 1047 HOH A O   1 
HETATM 8825 O  O   . HOH M 5 .   ? -19.134 -22.805 35.661  1   26.357 ? 1048 HOH A O   1 
HETATM 8826 O  O   . HOH M 5 .   ? -3.501  5.349   24.164  1   27.667 ? 1049 HOH A O   1 
HETATM 8827 O  O   . HOH M 5 .   ? -6.633  -25.688 43.339  1   40.62  ? 1050 HOH A O   1 
HETATM 8828 O  O   . HOH M 5 .   ? -19.254 -10.073 41.534  1   20.888 ? 1051 HOH A O   1 
HETATM 8829 O  O   . HOH M 5 .   ? -32.951 6.16    47.03   1   51.964 ? 1052 HOH A O   1 
HETATM 8830 O  O   . HOH M 5 .   ? 38.083  -22.404 6.394   1   37.466 ? 1053 HOH A O   1 
HETATM 8831 O  O   . HOH M 5 .   ? -18.521 -22.517 58.192  1   37.131 ? 1054 HOH A O   1 
HETATM 8832 O  O   . HOH M 5 .   ? -22.046 -7.829  63.06   1   33.437 ? 1055 HOH A O   1 
HETATM 8833 O  O   . HOH M 5 .   ? -2.597  -15.975 20.37   1   49.577 ? 1056 HOH A O   1 
HETATM 8834 O  O   . HOH M 5 .   ? 44.336  -22.731 15.941  1   47.111 ? 1057 HOH A O   1 
HETATM 8835 O  O   . HOH M 5 .   ? -13.41  11.602  38.757  1   21.149 ? 1058 HOH A O   1 
HETATM 8836 O  O   . HOH M 5 .   ? -3.675  1.403   37.212  1   20.658 ? 1059 HOH A O   1 
HETATM 8837 O  O   . HOH M 5 .   ? 13.613  -13.555 34.165  1   27.382 ? 1060 HOH A O   1 
HETATM 8838 O  O   . HOH M 5 .   ? -21.341 -25.064 41.815  1   51.865 ? 1061 HOH A O   1 
HETATM 8839 O  O   . HOH M 5 .   ? -37.914 17.888  41.273  1   66.647 ? 1062 HOH A O   1 
HETATM 8840 O  O   . HOH M 5 .   ? -29.367 -4.776  57.985  1   30.356 ? 1063 HOH A O   1 
HETATM 8841 O  O   . HOH M 5 .   ? 2.101   -15.051 20.159  1   53.049 ? 1064 HOH A O   1 
HETATM 8842 O  O   . HOH M 5 .   ? -11.309 4.618   64.387  1   55.207 ? 1065 HOH A O   1 
HETATM 8843 O  O   . HOH M 5 .   ? -40.035 -8.553  28.779  1   44.085 ? 1066 HOH A O   1 
HETATM 8844 O  O   . HOH M 5 .   ? -33.869 1.489   38.951  1   43.902 ? 1067 HOH A O   1 
HETATM 8845 O  O   . HOH M 5 .   ? 0.031   -4.811  23.896  1   28.961 ? 1068 HOH A O   1 
HETATM 8846 O  O   . HOH M 5 .   ? -14.965 6.392   23.793  1   46.635 ? 1069 HOH A O   1 
HETATM 8847 O  O   . HOH M 5 .   ? -13.673 7.532   33.893  1   37.106 ? 1070 HOH A O   1 
HETATM 8848 O  O   . HOH M 5 .   ? -27.881 -15.749 16.085  1   40.371 ? 1071 HOH A O   1 
HETATM 8849 O  O   . HOH M 5 .   ? -11.352 -11.512 67.447  1   49.641 ? 1072 HOH A O   1 
HETATM 8850 O  O   . HOH M 5 .   ? 19.844  8.291   45.699  1   61.978 ? 1073 HOH A O   1 
HETATM 8851 O  O   . HOH M 5 .   ? -26.326 20.695  33.414  1   49.761 ? 1074 HOH A O   1 
HETATM 8852 O  O   . HOH M 5 .   ? 8.249   1.179   59.044  1   49.126 ? 1075 HOH A O   1 
HETATM 8853 O  O   . HOH M 5 .   ? 6.985   -20.735 26.188  1   56.135 ? 1076 HOH A O   1 
HETATM 8854 O  O   . HOH M 5 .   ? 10.726  14.473  34.609  1   41.587 ? 1077 HOH A O   1 
HETATM 8855 O  O   . HOH M 5 .   ? -20.501 19.37   43.99   1   44.522 ? 1078 HOH A O   1 
HETATM 8856 O  O   . HOH M 5 .   ? -2.067  -13.472 44.453  1   29.801 ? 1079 HOH A O   1 
HETATM 8857 O  O   . HOH M 5 .   ? -30.217 -2.998  65.714  1   65.994 ? 1080 HOH A O   1 
HETATM 8858 O  O   . HOH M 5 .   ? -3.998  -6.812  46.368  1   39.316 ? 1081 HOH A O   1 
HETATM 8859 O  O   . HOH M 5 .   ? -17.173 -24.297 34.651  1   39.397 ? 1082 HOH A O   1 
HETATM 8860 O  O   . HOH M 5 .   ? -16.952 -20.603 14.678  1   46.461 ? 1083 HOH A O   1 
HETATM 8861 O  O   . HOH M 5 .   ? -17.222 3.148   14.29   1   59.807 ? 1084 HOH A O   1 
HETATM 8862 O  O   . HOH M 5 .   ? 1.165   4.016   18.093  1   27.994 ? 1085 HOH A O   1 
HETATM 8863 O  O   . HOH M 5 .   ? 11.516  3.557   55.66   1   68.418 ? 1086 HOH A O   1 
HETATM 8864 O  O   . HOH M 5 .   ? -7.132  12.794  29.6    1   50.685 ? 1087 HOH A O   1 
HETATM 8865 O  O   . HOH M 5 .   ? -17.094 -19.416 17.192  1   33.398 ? 1088 HOH A O   1 
HETATM 8866 O  O   . HOH M 5 .   ? 25.606  -27.706 21.476  1   56.467 ? 1089 HOH A O   1 
HETATM 8867 O  O   . HOH M 5 .   ? 21.525  -9.233  36.816  1   58.976 ? 1090 HOH A O   1 
HETATM 8868 O  O   . HOH M 5 .   ? -0.931  -18.865 46.496  1   40.224 ? 1091 HOH A O   1 
HETATM 8869 O  O   . HOH M 5 .   ? -7.135  -3.585  44.513  1   23.588 ? 1092 HOH A O   1 
HETATM 8870 O  O   . HOH M 5 .   ? 6.8     15.222  44.137  1   49.494 ? 1093 HOH A O   1 
HETATM 8871 O  O   . HOH M 5 .   ? -7.145  -15.365 7.424   1   41.636 ? 1094 HOH A O   1 
HETATM 8872 O  O   . HOH M 5 .   ? -20.432 -0.925  22.48   1   30.21  ? 1095 HOH A O   1 
HETATM 8873 O  O   . HOH M 5 .   ? -27.107 -7.368  66.887  1   64.596 ? 1096 HOH A O   1 
HETATM 8874 O  O   . HOH M 5 .   ? 13.699  -1.278  57.415  1   58.889 ? 1097 HOH A O   1 
HETATM 8875 O  O   . HOH M 5 .   ? -39.064 -4.991  27.541  1   40.664 ? 1098 HOH A O   1 
HETATM 8876 O  O   . HOH M 5 .   ? -6.175  -5.739  47.251  1   30.873 ? 1099 HOH A O   1 
HETATM 8877 O  O   . HOH M 5 .   ? 14.829  -17.237 34.285  1   29.267 ? 1100 HOH A O   1 
HETATM 8878 O  O   . HOH M 5 .   ? 3.283   16.515  48.88   1   52.616 ? 1101 HOH A O   1 
HETATM 8879 O  O   . HOH M 5 .   ? -30.962 -15.137 50.007  1   37.45  ? 1102 HOH A O   1 
HETATM 8880 O  O   . HOH M 5 .   ? -7.597  17.849  44.68   1   37.769 ? 1103 HOH A O   1 
HETATM 8881 O  O   . HOH M 5 .   ? -1.39   -18.869 55.3    1   45.965 ? 1104 HOH A O   1 
HETATM 8882 O  O   . HOH M 5 .   ? -5.161  -10.416 46.189  1   46.273 ? 1105 HOH A O   1 
HETATM 8883 O  O   . HOH M 5 .   ? 0.969   -15.637 22.316  1   37.494 ? 1106 HOH A O   1 
HETATM 8884 O  O   . HOH M 5 .   ? -34.352 -9.944  40.18   1   39.062 ? 1107 HOH A O   1 
HETATM 8885 O  O   . HOH M 5 .   ? 26.343  -30.501 5.309   1   30.346 ? 1108 HOH A O   1 
HETATM 8886 O  O   . HOH M 5 .   ? -7.865  -26.783 34.235  1   49.897 ? 1109 HOH A O   1 
HETATM 8887 O  O   . HOH M 5 .   ? -16.997 -10.989 65.407  1   51.459 ? 1110 HOH A O   1 
HETATM 8888 O  O   . HOH M 5 .   ? 5.844   -23.52  30.056  1   43.027 ? 1111 HOH A O   1 
HETATM 8889 O  O   . HOH M 5 .   ? -34.685 -11.352 36.124  1   30.723 ? 1112 HOH A O   1 
HETATM 8890 O  O   . HOH M 5 .   ? -14.64  9.28    32.09   1   40.451 ? 1113 HOH A O   1 
HETATM 8891 O  O   . HOH M 5 .   ? 21.638  -31.911 23.263  1   50.5   ? 1114 HOH A O   1 
HETATM 8892 O  O   . HOH M 5 .   ? -35.041 -7.168  37.852  1   34.473 ? 1115 HOH A O   1 
HETATM 8893 O  O   . HOH M 5 .   ? -17.775 14.748  34.382  1   46.233 ? 1116 HOH A O   1 
HETATM 8894 O  O   . HOH M 5 .   ? 4.878   16.31   46.734  1   61.082 ? 1117 HOH A O   1 
HETATM 8895 O  O   . HOH M 5 .   ? -27.552 5.954   30.68   1   39.403 ? 1118 HOH A O   1 
HETATM 8896 O  O   . HOH M 5 .   ? -16.616 4.028   12.108  1   60.984 ? 1119 HOH A O   1 
HETATM 8897 O  O   . HOH M 5 .   ? -21.747 3.817   63.434  1   29.511 ? 1120 HOH A O   1 
HETATM 8898 O  O   . HOH M 5 .   ? 1.096   -23.947 25.603  1   45.609 ? 1121 HOH A O   1 
HETATM 8899 O  O   . HOH M 5 .   ? 1.47    -12.357 48.039  1   39.443 ? 1122 HOH A O   1 
HETATM 8900 O  O   . HOH M 5 .   ? 0.63    -24.227 36.814  1   29.172 ? 1123 HOH A O   1 
HETATM 8901 O  O   . HOH M 5 .   ? -1.822  -20.642 51.997  1   40.036 ? 1124 HOH A O   1 
HETATM 8902 O  O   . HOH M 5 .   ? -27.725 4.757   26.527  1   39.54  ? 1125 HOH A O   1 
HETATM 8903 O  O   . HOH M 5 .   ? 12.253  -16.458 34.894  1   28.229 ? 1126 HOH A O   1 
HETATM 8904 O  O   . HOH M 5 .   ? -18.26  4.644   65.399  1   33.398 ? 1127 HOH A O   1 
HETATM 8905 O  O   . HOH M 5 .   ? -31.532 4.556   28.743  1   43.152 ? 1128 HOH A O   1 
HETATM 8906 O  O   . HOH M 5 .   ? 17.821  -7.86   53.229  1   51.403 ? 1129 HOH A O   1 
HETATM 8907 O  O   . HOH M 5 .   ? -7.398  10.454  1       1   37.574 ? 1130 HOH A O   1 
HETATM 8908 O  O   . HOH M 5 .   ? 45.714  -18.498 4.179   1   43.282 ? 1131 HOH A O   1 
HETATM 8909 O  O   . HOH M 5 .   ? -20.089 -16.493 15.352  1   46.621 ? 1132 HOH A O   1 
HETATM 8910 O  O   . HOH M 5 .   ? -4.68   -10.702 63.817  1   47.505 ? 1133 HOH A O   1 
HETATM 8911 O  O   . HOH N 5 .   ? 20.775  12.873  2.281   1   37.589 ? 701  HOH B O   1 
HETATM 8912 O  O   . HOH N 5 .   ? 21.174  -6.641  1.646   1   30.485 ? 702  HOH B O   1 
HETATM 8913 O  O   . HOH N 5 .   ? 40.738  -21.196 -4.186  1   46.365 ? 703  HOH B O   1 
HETATM 8914 O  O   . HOH N 5 .   ? 5.744   10.338  10.98   1   39.209 ? 704  HOH B O   1 
HETATM 8915 O  O   . HOH N 5 .   ? 14.875  0.372   13.578  1   45.891 ? 705  HOH B O   1 
HETATM 8916 O  O   . HOH N 5 .   ? 5.743   -2.345  -16.439 1   37.525 ? 706  HOH B O   1 
HETATM 8917 O  O   . HOH N 5 .   ? 41.412  9.802   7.346   1   45.231 ? 707  HOH B O   1 
HETATM 8918 O  O   . HOH N 5 .   ? 0.286   -23.747 14.965  1   42.985 ? 708  HOH B O   1 
HETATM 8919 O  O   . HOH N 5 .   ? 39.241  -22.533 -16.07  1   46.964 ? 709  HOH B O   1 
HETATM 8920 O  O   . HOH N 5 .   ? 19.209  7.09    -19.471 1   49.042 ? 710  HOH B O   1 
HETATM 8921 O  O   . HOH N 5 .   ? 2.949   -25.808 8.79    1   39.415 ? 711  HOH B O   1 
HETATM 8922 O  O   . HOH N 5 .   ? -3.577  -18.05  5.707   1   32.285 ? 712  HOH B O   1 
HETATM 8923 O  O   . HOH N 5 .   ? 26.003  -15.465 -24.907 1   37.732 ? 713  HOH B O   1 
HETATM 8924 O  O   . HOH N 5 .   ? 0.44    5.514   -11.386 1   37.589 ? 714  HOH B O   1 
HETATM 8925 O  O   . HOH N 5 .   ? 22.516  1.577   -21.76  1   30.414 ? 715  HOH B O   1 
HETATM 8926 O  O   . HOH N 5 .   ? -21.553 -15.448 34.195  1   26.262 ? 716  HOH B O   1 
HETATM 8927 O  O   . HOH N 5 .   ? 4.121   15.482  -1.702  1   36.662 ? 717  HOH B O   1 
HETATM 8928 O  O   . HOH N 5 .   ? 34.218  6.33    -0.725  1   27.437 ? 718  HOH B O   1 
HETATM 8929 O  O   . HOH N 5 .   ? -5.04   -1.506  -13.965 1   43.323 ? 719  HOH B O   1 
HETATM 8930 O  O   . HOH N 5 .   ? 28.242  9.036   4.313   1   44.229 ? 720  HOH B O   1 
HETATM 8931 O  O   . HOH N 5 .   ? -8.22   -3.435  -8.506  1   34.273 ? 721  HOH B O   1 
HETATM 8932 O  O   . HOH N 5 .   ? -6.944  0.546   -5.913  1   47.381 ? 722  HOH B O   1 
HETATM 8933 O  O   . HOH N 5 .   ? 31.718  -18.87  -22.054 1   37.937 ? 723  HOH B O   1 
HETATM 8934 O  O   . HOH N 5 .   ? 42.436  -5.411  -1.383  1   35.978 ? 724  HOH B O   1 
HETATM 8935 O  O   . HOH N 5 .   ? 2.368   -25.283 6.29    1   30.502 ? 725  HOH B O   1 
HETATM 8936 O  O   . HOH N 5 .   ? 39.232  -0.179  -14.276 1   44.89  ? 726  HOH B O   1 
HETATM 8937 O  O   . HOH N 5 .   ? 9.607   -2.399  3.138   1   21.104 ? 727  HOH B O   1 
HETATM 8938 O  O   . HOH N 5 .   ? 33.582  7.945   1.413   1   23.647 ? 728  HOH B O   1 
HETATM 8939 O  O   . HOH N 5 .   ? 34.145  -7.783  9.929   1   21.772 ? 729  HOH B O   1 
HETATM 8940 O  O   . HOH N 5 .   ? 31.669  -13.998 -23.986 1   39.37  ? 730  HOH B O   1 
HETATM 8941 O  O   . HOH N 5 .   ? 19.004  -30.939 -2.652  1   39.187 ? 731  HOH B O   1 
HETATM 8942 O  O   . HOH N 5 .   ? 18.118  -14.766 14.868  1   20.267 ? 732  HOH B O   1 
HETATM 8943 O  O   . HOH N 5 .   ? 27.079  -24.439 -21.2   1   44.75  ? 733  HOH B O   1 
HETATM 8944 O  O   . HOH N 5 .   ? -2.613  4.264   -5.321  1   28.679 ? 734  HOH B O   1 
HETATM 8945 O  O   . HOH N 5 .   ? 13.13   -19.386 20.064  1   36.979 ? 735  HOH B O   1 
HETATM 8946 O  O   . HOH N 5 .   ? 18.795  2.338   -22.485 1   51.809 ? 736  HOH B O   1 
HETATM 8947 O  O   . HOH N 5 .   ? 26.101  -17.314 30.51   1   37.588 ? 737  HOH B O   1 
HETATM 8948 O  O   . HOH N 5 .   ? -11.087 -4.82   1.533   1   45.82  ? 738  HOH B O   1 
HETATM 8949 O  O   . HOH N 5 .   ? 18.311  -5.184  18.903  1   21.443 ? 739  HOH B O   1 
HETATM 8950 O  O   . HOH N 5 .   ? 32.051  -15.657 7.474   1   24.057 ? 740  HOH B O   1 
HETATM 8951 O  O   . HOH N 5 .   ? 34.632  -12.555 -24.148 1   44.196 ? 741  HOH B O   1 
HETATM 8952 O  O   . HOH N 5 .   ? -6.706  -8.87   0.839   1   27.77  ? 742  HOH B O   1 
HETATM 8953 O  O   . HOH N 5 .   ? 23.771  2.322   8.12    1   36.141 ? 743  HOH B O   1 
HETATM 8954 O  O   . HOH N 5 .   ? 31.835  6.276   2.641   1   28.915 ? 744  HOH B O   1 
HETATM 8955 O  O   . HOH N 5 .   ? -5.957  -7.824  -13.116 1   42.448 ? 745  HOH B O   1 
HETATM 8956 O  O   . HOH N 5 .   ? 40.218  -22.984 -1.355  1   34.925 ? 746  HOH B O   1 
HETATM 8957 O  O   . HOH N 5 .   ? -9.564  0.017   7.105   1   41.711 ? 747  HOH B O   1 
HETATM 8958 O  O   . HOH N 5 .   ? 17.374  2.558   23.814  1   59.307 ? 748  HOH B O   1 
HETATM 8959 O  O   . HOH N 5 .   ? 34.71   -26.879 -11.762 1   30.169 ? 749  HOH B O   1 
HETATM 8960 O  O   . HOH N 5 .   ? 26.777  -11.179 19.868  1   25.272 ? 750  HOH B O   1 
HETATM 8961 O  O   . HOH N 5 .   ? 23.751  -14.067 -24.666 1   35.654 ? 751  HOH B O   1 
HETATM 8962 O  O   . HOH N 5 .   ? -35.526 -13.051 26.473  1   44.203 ? 752  HOH B O   1 
HETATM 8963 O  O   . HOH N 5 .   ? 6.877   -24.272 4.078   1   26.244 ? 753  HOH B O   1 
HETATM 8964 O  O   . HOH N 5 .   ? 27.195  -7.853  -5.133  1   21.882 ? 754  HOH B O   1 
HETATM 8965 O  O   . HOH N 5 .   ? 24.059  -12.288 -0.505  1   20.184 ? 755  HOH B O   1 
HETATM 8966 O  O   . HOH N 5 .   ? 32.418  -26.834 -21.227 1   49.552 ? 756  HOH B O   1 
HETATM 8967 O  O   . HOH N 5 .   ? -38.476 -13.057 28.522  1   29.47  ? 757  HOH B O   1 
HETATM 8968 O  O   . HOH N 5 .   ? 33.709  -10.202 26.565  1   33.041 ? 758  HOH B O   1 
HETATM 8969 O  O   . HOH N 5 .   ? 21.606  -12.756 20.59   1   20.764 ? 759  HOH B O   1 
HETATM 8970 O  O   . HOH N 5 .   ? -3.978  -27.067 4.32    1   33.417 ? 760  HOH B O   1 
HETATM 8971 O  O   . HOH N 5 .   ? 1.248   9.281   1.509   1   31.231 ? 761  HOH B O   1 
HETATM 8972 O  O   . HOH N 5 .   ? 16.618  -13.579 -3.394  1   24.871 ? 762  HOH B O   1 
HETATM 8973 O  O   . HOH N 5 .   ? 10.543  0.031   10.652  1   27.039 ? 763  HOH B O   1 
HETATM 8974 O  O   . HOH N 5 .   ? 24.22   9.144   6.912   1   39.891 ? 764  HOH B O   1 
HETATM 8975 O  O   . HOH N 5 .   ? 16.167  -12.067 -22.06  1   29.179 ? 765  HOH B O   1 
HETATM 8976 O  O   . HOH N 5 .   ? 23.497  -3.6    15.304  1   26.907 ? 766  HOH B O   1 
HETATM 8977 O  O   . HOH N 5 .   ? 24.812  -32.026 -1.507  1   35.045 ? 767  HOH B O   1 
HETATM 8978 O  O   . HOH N 5 .   ? 14.37   -0.018  15.994  1   28.541 ? 768  HOH B O   1 
HETATM 8979 O  O   . HOH N 5 .   ? 14.762  -10.656 -15.064 1   24.21  ? 769  HOH B O   1 
HETATM 8980 O  O   . HOH N 5 .   ? 20.47   -32.602 -13.438 1   45.776 ? 770  HOH B O   1 
HETATM 8981 O  O   . HOH N 5 .   ? 9.274   -24.077 5.375   1   22.659 ? 771  HOH B O   1 
HETATM 8982 O  O   . HOH N 5 .   ? -37.256 -10.801 35.187  1   28.762 ? 772  HOH B O   1 
HETATM 8983 O  O   . HOH N 5 .   ? 44.799  9.309   0.445   1   34.275 ? 773  HOH B O   1 
HETATM 8984 O  O   . HOH N 5 .   ? 9.374   -6.038  -13.626 1   24.304 ? 774  HOH B O   1 
HETATM 8985 O  O   . HOH N 5 .   ? 32.302  -11.839 -31.26  1   58.834 ? 775  HOH B O   1 
HETATM 8986 O  O   . HOH N 5 .   ? 9.411   -28.307 5.525   1   43.024 ? 776  HOH B O   1 
HETATM 8987 O  O   . HOH N 5 .   ? -8.502  3.885   0.067   1   42.811 ? 777  HOH B O   1 
HETATM 8988 O  O   . HOH N 5 .   ? 14.063  -27.567 -13.522 1   29.566 ? 778  HOH B O   1 
HETATM 8989 O  O   . HOH N 5 .   ? 10.979  -13.434 22.999  1   22.001 ? 779  HOH B O   1 
HETATM 8990 O  O   . HOH N 5 .   ? 10.121  2.904   12.803  1   54.167 ? 780  HOH B O   1 
HETATM 8991 O  O   . HOH N 5 .   ? 29.494  -0.02   16.037  1   34.25  ? 781  HOH B O   1 
HETATM 8992 O  O   . HOH N 5 .   ? 22.863  -18.13  6.54    1   20.813 ? 782  HOH B O   1 
HETATM 8993 O  O   . HOH N 5 .   ? -2.537  -8.328  -5.66   1   29.876 ? 783  HOH B O   1 
HETATM 8994 O  O   . HOH N 5 .   ? -8.828  -3.098  -5.257  1   43.473 ? 784  HOH B O   1 
HETATM 8995 O  O   . HOH N 5 .   ? 26.896  1.022   -21.074 1   32.324 ? 785  HOH B O   1 
HETATM 8996 O  O   . HOH N 5 .   ? 31.342  9.877   -11.672 1   52.395 ? 786  HOH B O   1 
HETATM 8997 O  O   . HOH N 5 .   ? 30.726  -16.493 -19.599 1   23.358 ? 787  HOH B O   1 
HETATM 8998 O  O   . HOH N 5 .   ? 17.198  -0.381  6.758   1   26.281 ? 788  HOH B O   1 
HETATM 8999 O  O   . HOH N 5 .   ? 6.542   -1.538  -18.899 1   35.434 ? 789  HOH B O   1 
HETATM 9000 O  O   . HOH N 5 .   ? 2.046   -16.16  1.586   1   25.04  ? 790  HOH B O   1 
HETATM 9001 O  O   . HOH N 5 .   ? 16.893  11.848  2.644   1   43.827 ? 791  HOH B O   1 
HETATM 9002 O  O   . HOH N 5 .   ? 12.139  -23.524 20.255  1   38.16  ? 792  HOH B O   1 
HETATM 9003 O  O   . HOH N 5 .   ? 12.043  -19.213 14.716  1   21.198 ? 793  HOH B O   1 
HETATM 9004 O  O   . HOH N 5 .   ? -2.451  -11.926 18.352  1   18.857 ? 794  HOH B O   1 
HETATM 9005 O  O   . HOH N 5 .   ? 16.417  -5.067  -3.291  1   23.109 ? 795  HOH B O   1 
HETATM 9006 O  O   . HOH N 5 .   ? 41.839  -12.555 -2.191  1   29.337 ? 796  HOH B O   1 
HETATM 9007 O  O   . HOH N 5 .   ? -7.418  -12.229 -0.264  1   30.875 ? 797  HOH B O   1 
HETATM 9008 O  O   . HOH N 5 .   ? 23.546  -21.705 -20.759 1   48.34  ? 798  HOH B O   1 
HETATM 9009 O  O   . HOH N 5 .   ? 20.126  -14.488 -25.768 1   56.241 ? 799  HOH B O   1 
HETATM 9010 O  O   . HOH N 5 .   ? 20.206  16.434  -1.975  1   50.644 ? 800  HOH B O   1 
HETATM 9011 O  O   . HOH N 5 .   ? 22.255  4.597   -5.46   1   24.726 ? 801  HOH B O   1 
HETATM 9012 O  O   . HOH N 5 .   ? 11.644  -27.068 -14.242 1   36.796 ? 802  HOH B O   1 
HETATM 9013 O  O   . HOH N 5 .   ? 18.512  -7.916  -6.02   1   21.994 ? 803  HOH B O   1 
HETATM 9014 O  O   . HOH N 5 .   ? -16.469 -19.75  20.056  1   27.214 ? 804  HOH B O   1 
HETATM 9015 O  O   . HOH N 5 .   ? 12.464  -29.354 -0.77   1   48.472 ? 805  HOH B O   1 
HETATM 9016 O  O   . HOH N 5 .   ? 43.094  -19.882 -6.654  1   59.48  ? 806  HOH B O   1 
HETATM 9017 O  O   . HOH N 5 .   ? 6.177   -12.448 -5.627  1   33.834 ? 807  HOH B O   1 
HETATM 9018 O  O   . HOH N 5 .   ? 29.529  -21.508 -22.59  1   37.966 ? 808  HOH B O   1 
HETATM 9019 O  O   . HOH N 5 .   ? 23.96   -19.524 13.183  1   19.971 ? 809  HOH B O   1 
HETATM 9020 O  O   . HOH N 5 .   ? 34.666  -28.444 6.193   1   56.821 ? 810  HOH B O   1 
HETATM 9021 O  O   . HOH N 5 .   ? 20.825  -15.007 14.786  1   19.431 ? 811  HOH B O   1 
HETATM 9022 O  O   . HOH N 5 .   ? 22.678  11.245  -7.497  1   36.74  ? 812  HOH B O   1 
HETATM 9023 O  O   . HOH N 5 .   ? 39.348  13.989  10.656  1   24.845 ? 813  HOH B O   1 
HETATM 9024 O  O   . HOH N 5 .   ? -21.544 -20.917 27.445  1   51.528 ? 814  HOH B O   1 
HETATM 9025 O  O   . HOH N 5 .   ? -2.947  -14.776 8.969   1   23.773 ? 815  HOH B O   1 
HETATM 9026 O  O   . HOH N 5 .   ? 36.294  -27.31  -5.9    1   34.783 ? 816  HOH B O   1 
HETATM 9027 O  O   . HOH N 5 .   ? -1.657  -22.592 -0.609  1   37.974 ? 817  HOH B O   1 
HETATM 9028 O  O   . HOH N 5 .   ? 9.7     -22.642 -8.307  1   29.149 ? 818  HOH B O   1 
HETATM 9029 O  O   . HOH N 5 .   ? 2.267   4.381   -15.35  1   61.878 ? 819  HOH B O   1 
HETATM 9030 O  O   . HOH N 5 .   ? 18.433  -2.663  8.65    1   30.045 ? 820  HOH B O   1 
HETATM 9031 O  O   . HOH N 5 .   ? 34.696  -4.977  -7.374  1   42.772 ? 821  HOH B O   1 
HETATM 9032 O  O   . HOH N 5 .   ? 37.706  -2.864  7.082   1   23.242 ? 822  HOH B O   1 
HETATM 9033 O  O   . HOH N 5 .   ? 9.692   18.104  0.703   1   56.585 ? 823  HOH B O   1 
HETATM 9034 O  O   . HOH N 5 .   ? 19.775  -25.414 1.698   1   22.802 ? 824  HOH B O   1 
HETATM 9035 O  O   . HOH N 5 .   ? -0.328  -15.469 19.14   1   38.58  ? 825  HOH B O   1 
HETATM 9036 O  O   . HOH N 5 .   ? 12.612  -17.53  18.145  1   29.678 ? 826  HOH B O   1 
HETATM 9037 O  O   . HOH N 5 .   ? 23.033  -23.511 18.988  1   22.459 ? 827  HOH B O   1 
HETATM 9038 O  O   . HOH N 5 .   ? 28.084  -1.101  -19.034 1   39.387 ? 828  HOH B O   1 
HETATM 9039 O  O   . HOH N 5 .   ? 29.56   -7.518  15.811  1   34.171 ? 829  HOH B O   1 
HETATM 9040 O  O   . HOH N 5 .   ? 15.264  5.194   -19.101 1   39.096 ? 830  HOH B O   1 
HETATM 9041 O  O   . HOH N 5 .   ? 3.904   6.824   3.715   1   27.974 ? 831  HOH B O   1 
HETATM 9042 O  O   . HOH N 5 .   ? 23.745  -11.793 3.414   1   20.68  ? 832  HOH B O   1 
HETATM 9043 O  O   . HOH N 5 .   ? 31.032  -6.167  13.154  1   25.009 ? 833  HOH B O   1 
HETATM 9044 O  O   . HOH N 5 .   ? 18.21   8.697   38.509  1   40.047 ? 834  HOH B O   1 
HETATM 9045 O  O   . HOH N 5 .   ? 15.247  -17.565 -17.4   1   24.646 ? 835  HOH B O   1 
HETATM 9046 O  O   . HOH N 5 .   ? -6.119  4.362   12.636  1   35.58  ? 836  HOH B O   1 
HETATM 9047 O  O   . HOH N 5 .   ? 39.795  -20.321 6.292   1   27     ? 837  HOH B O   1 
HETATM 9048 O  O   . HOH N 5 .   ? 28.955  -6.52   -30.307 1   55.525 ? 838  HOH B O   1 
HETATM 9049 O  O   . HOH N 5 .   ? -6.69   -5.94   9.322   1   22.352 ? 839  HOH B O   1 
HETATM 9050 O  O   . HOH N 5 .   ? 41.725  -1.198  8.566   1   43.898 ? 840  HOH B O   1 
HETATM 9051 O  O   . HOH N 5 .   ? -5.037  -5.826  -14.796 1   41.907 ? 841  HOH B O   1 
HETATM 9052 O  O   . HOH N 5 .   ? 16.919  -5.478  -31.784 1   40.355 ? 842  HOH B O   1 
HETATM 9053 O  O   . HOH N 5 .   ? 5.298   -24.588 13.919  1   33.924 ? 843  HOH B O   1 
HETATM 9054 O  O   . HOH N 5 .   ? 15.576  -1.797  -13.841 1   27.609 ? 844  HOH B O   1 
HETATM 9055 O  O   . HOH N 5 .   ? 25.772  -0.538  14.831  1   27.852 ? 845  HOH B O   1 
HETATM 9056 O  O   . HOH N 5 .   ? 13.113  -11.379 22.747  1   21.177 ? 846  HOH B O   1 
HETATM 9057 O  O   . HOH N 5 .   ? 36.999  5.805   -19.209 1   56.453 ? 847  HOH B O   1 
HETATM 9058 O  O   . HOH N 5 .   ? 26.64   -24.349 14.451  1   20.365 ? 848  HOH B O   1 
HETATM 9059 O  O   . HOH N 5 .   ? 40.498  2.183   -9.165  1   56.048 ? 849  HOH B O   1 
HETATM 9060 O  O   . HOH N 5 .   ? 16.817  5.199   4.904   1   25.19  ? 850  HOH B O   1 
HETATM 9061 O  O   . HOH N 5 .   ? -23.812 -22.536 36.715  1   34.375 ? 851  HOH B O   1 
HETATM 9062 O  O   . HOH N 5 .   ? 14.587  -27.922 7.579   1   36.205 ? 852  HOH B O   1 
HETATM 9063 O  O   . HOH N 5 .   ? 12.357  1.463   14.238  1   39.187 ? 853  HOH B O   1 
HETATM 9064 O  O   . HOH N 5 .   ? -11.958 -5.842  11.532  1   33.064 ? 854  HOH B O   1 
HETATM 9065 O  O   . HOH N 5 .   ? 36.153  -23.876 -6.477  1   27.017 ? 855  HOH B O   1 
HETATM 9066 O  O   . HOH N 5 .   ? 12.068  -10.232 17.159  1   26.694 ? 856  HOH B O   1 
HETATM 9067 O  O   . HOH N 5 .   ? -9.356  -7.183  -9.405  1   51.157 ? 857  HOH B O   1 
HETATM 9068 O  O   . HOH N 5 .   ? 42.705  -13.023 0.667   1   44.794 ? 858  HOH B O   1 
HETATM 9069 O  O   . HOH N 5 .   ? 18.159  -10.988 -11.555 1   23.329 ? 859  HOH B O   1 
HETATM 9070 O  O   . HOH N 5 .   ? 29.761  -10.64  3.662   1   21.062 ? 860  HOH B O   1 
HETATM 9071 O  O   . HOH N 5 .   ? 25.419  -9.806  26.289  1   22.169 ? 861  HOH B O   1 
HETATM 9072 O  O   . HOH N 5 .   ? 24.442  0.271   -20.458 1   26.662 ? 862  HOH B O   1 
HETATM 9073 O  O   . HOH N 5 .   ? 33.894  -0.63   11.992  1   33.672 ? 863  HOH B O   1 
HETATM 9074 O  O   . HOH N 5 .   ? 13.902  -14.081 -2.42   1   26.757 ? 864  HOH B O   1 
HETATM 9075 O  O   . HOH N 5 .   ? 17.584  -3.919  -16.853 1   31.48  ? 865  HOH B O   1 
HETATM 9076 O  O   . HOH N 5 .   ? 29.108  -10.667 14.39   1   23.724 ? 866  HOH B O   1 
HETATM 9077 O  O   . HOH N 5 .   ? -36.97  -16.926 34.467  1   48.963 ? 867  HOH B O   1 
HETATM 9078 O  O   . HOH N 5 .   ? 29.659  -12.99  12.381  1   22.837 ? 868  HOH B O   1 
HETATM 9079 O  O   . HOH N 5 .   ? 44.468  7.524   -2.96   1   47.342 ? 869  HOH B O   1 
HETATM 9080 O  O   . HOH N 5 .   ? 17.87   -13.888 23.146  1   18.854 ? 870  HOH B O   1 
HETATM 9081 O  O   . HOH N 5 .   ? 25.929  7.598   -1.266  1   29.569 ? 871  HOH B O   1 
HETATM 9082 O  O   . HOH N 5 .   ? 30.005  -15.89  1.788   1   19.531 ? 872  HOH B O   1 
HETATM 9083 O  O   . HOH N 5 .   ? -4.563  -15.87  11.599  1   32.552 ? 873  HOH B O   1 
HETATM 9084 O  O   . HOH N 5 .   ? -5.512  -12.925 -14.211 1   57.834 ? 874  HOH B O   1 
HETATM 9085 O  O   . HOH N 5 .   ? 26.522  -13.681 10.907  1   21.018 ? 875  HOH B O   1 
HETATM 9086 O  O   . HOH N 5 .   ? 26.087  -13.87  -1.684  1   19.809 ? 876  HOH B O   1 
HETATM 9087 O  O   . HOH N 5 .   ? 29.383  -11.05  26.362  1   29.723 ? 877  HOH B O   1 
HETATM 9088 O  O   . HOH N 5 .   ? 24.722  -21.326 25.299  1   23.37  ? 878  HOH B O   1 
HETATM 9089 O  O   . HOH N 5 .   ? 37.084  -12.171 21.188  1   34.506 ? 879  HOH B O   1 
HETATM 9090 O  O   . HOH N 5 .   ? 13.711  -1.695  -15.901 1   29.754 ? 880  HOH B O   1 
HETATM 9091 O  O   . HOH N 5 .   ? 42.006  -2.002  1.455   1   24.801 ? 881  HOH B O   1 
HETATM 9092 O  O   . HOH N 5 .   ? -8.366  -3.878  -14.16  1   56.706 ? 882  HOH B O   1 
HETATM 9093 O  O   . HOH N 5 .   ? 4.975   -10.592 -9.399  1   27.731 ? 883  HOH B O   1 
HETATM 9094 O  O   . HOH N 5 .   ? 33.672  -6.765  25.777  1   27.614 ? 884  HOH B O   1 
HETATM 9095 O  O   . HOH N 5 .   ? 6.248   -5.066  -20.283 1   50.934 ? 885  HOH B O   1 
HETATM 9096 O  O   . HOH N 5 .   ? 35.424  -6.492  -19.021 1   24.699 ? 886  HOH B O   1 
HETATM 9097 O  O   . HOH N 5 .   ? 13.897  -4.282  23.283  1   23.38  ? 887  HOH B O   1 
HETATM 9098 O  O   . HOH N 5 .   ? 15.95   -30.152 11.153  1   39.912 ? 888  HOH B O   1 
HETATM 9099 O  O   . HOH N 5 .   ? 35.592  13.669  8.08    1   36.755 ? 889  HOH B O   1 
HETATM 9100 O  O   . HOH N 5 .   ? 18.02   -9.226  -9.32   1   22.442 ? 890  HOH B O   1 
HETATM 9101 O  O   . HOH N 5 .   ? 9.195   -6.847  -20.023 1   31.675 ? 891  HOH B O   1 
HETATM 9102 O  O   . HOH N 5 .   ? 9.667   -10.994 -20.952 1   39.869 ? 892  HOH B O   1 
HETATM 9103 O  O   . HOH N 5 .   ? 20.937  -34.395 -0.573  1   42.051 ? 893  HOH B O   1 
HETATM 9104 O  O   . HOH N 5 .   ? 12.507  -24.757 16.584  1   29.313 ? 894  HOH B O   1 
HETATM 9105 O  O   . HOH N 5 .   ? 14.048  2.963   7.424   1   23.781 ? 895  HOH B O   1 
HETATM 9106 O  O   . HOH N 5 .   ? 47.303  -12.178 12.127  1   23.257 ? 896  HOH B O   1 
HETATM 9107 O  O   . HOH N 5 .   ? 24.441  10.922  -2.079  1   44.547 ? 897  HOH B O   1 
HETATM 9108 O  O   . HOH N 5 .   ? 2.982   3.258   -11.382 1   30.684 ? 898  HOH B O   1 
HETATM 9109 O  O   . HOH N 5 .   ? 26.427  -11.082 12.034  1   23.642 ? 899  HOH B O   1 
HETATM 9110 O  O   . HOH N 5 .   ? 12.216  -8.552  -7.32   1   29.8   ? 900  HOH B O   1 
HETATM 9111 O  O   . HOH N 5 .   ? 12.427  -29.411 12.822  1   31.788 ? 901  HOH B O   1 
HETATM 9112 O  O   . HOH N 5 .   ? 29.593  -4.747  -23.067 1   26.026 ? 902  HOH B O   1 
HETATM 9113 O  O   . HOH N 5 .   ? 35.974  5.286   -6.218  1   43.302 ? 903  HOH B O   1 
HETATM 9114 O  O   . HOH N 5 .   ? 20.842  -21.678 -20.985 1   41.07  ? 904  HOH B O   1 
HETATM 9115 O  O   . HOH N 5 .   ? 26.442  -8.415  28.201  1   38.344 ? 905  HOH B O   1 
HETATM 9116 O  O   . HOH N 5 .   ? 11.176  -3.897  8.237   1   27.066 ? 906  HOH B O   1 
HETATM 9117 O  O   . HOH N 5 .   ? 36.188  -10.585 23.857  1   32.375 ? 907  HOH B O   1 
HETATM 9118 O  O   . HOH N 5 .   ? 10.659  -5.376  1.427   1   19.893 ? 908  HOH B O   1 
HETATM 9119 O  O   . HOH N 5 .   ? 8.999   -9.777  -3.567  1   22.177 ? 909  HOH B O   1 
HETATM 9120 O  O   . HOH N 5 .   ? 41.784  -14.98  -0.112  1   46.54  ? 910  HOH B O   1 
HETATM 9121 O  O   . HOH N 5 .   ? 4.286   1.621   21.115  1   25.236 ? 911  HOH B O   1 
HETATM 9122 O  O   . HOH N 5 .   ? -16.41  -18.959 22.659  1   22.364 ? 912  HOH B O   1 
HETATM 9123 O  O   . HOH N 5 .   ? -34.95  -11.908 26.081  1   34.565 ? 913  HOH B O   1 
HETATM 9124 O  O   . HOH N 5 .   ? 28.135  -9.964  17.686  1   24.792 ? 914  HOH B O   1 
HETATM 9125 O  O   . HOH N 5 .   ? 25.616  -5.821  28.78   1   44.836 ? 915  HOH B O   1 
HETATM 9126 O  O   . HOH N 5 .   ? 34.261  -6.276  -22.525 1   35.642 ? 916  HOH B O   1 
HETATM 9127 O  O   . HOH N 5 .   ? 9.932   -16.581 -3.059  1   27.715 ? 917  HOH B O   1 
HETATM 9128 O  O   . HOH N 5 .   ? 22.499  -5.162  13.345  1   26.884 ? 918  HOH B O   1 
HETATM 9129 O  O   . HOH N 5 .   ? 8.51    -7.246  -5.987  1   22.649 ? 919  HOH B O   1 
HETATM 9130 O  O   . HOH N 5 .   ? 44.696  -7.572  -3.908  1   53.817 ? 920  HOH B O   1 
HETATM 9131 O  O   . HOH N 5 .   ? 16.077  3.439   -20.946 1   46.211 ? 921  HOH B O   1 
HETATM 9132 O  O   . HOH N 5 .   ? 23.519  8.812   -0.452  1   29.574 ? 922  HOH B O   1 
HETATM 9133 O  O   . HOH N 5 .   ? 32.511  -4.863  18.685  1   28.154 ? 923  HOH B O   1 
HETATM 9134 O  O   . HOH N 5 .   ? 25.821  -30.458 2.714   1   29.842 ? 924  HOH B O   1 
HETATM 9135 O  O   . HOH N 5 .   ? 40.942  -19.662 -1.942  1   28.548 ? 925  HOH B O   1 
HETATM 9136 O  O   . HOH N 5 .   ? -0.598  2.783   16.184  1   28.856 ? 926  HOH B O   1 
HETATM 9137 O  O   . HOH N 5 .   ? 48.971  1.962   5.776   1   35.169 ? 927  HOH B O   1 
HETATM 9138 O  O   . HOH N 5 .   ? 34.398  2.509   -19.559 1   42.104 ? 928  HOH B O   1 
HETATM 9139 O  O   . HOH N 5 .   ? 15.543  -7.183  -7.254  1   26.616 ? 929  HOH B O   1 
HETATM 9140 O  O   . HOH N 5 .   ? 38.47   6.565   6.7     1   41.438 ? 930  HOH B O   1 
HETATM 9141 O  O   . HOH N 5 .   ? 33.31   5.32    -7.907  1   42.798 ? 931  HOH B O   1 
HETATM 9142 O  O   . HOH N 5 .   ? 35.45   3.607   9.219   1   36.955 ? 932  HOH B O   1 
HETATM 9143 O  O   . HOH N 5 .   ? -6.605  -8.782  17.854  1   22.075 ? 933  HOH B O   1 
HETATM 9144 O  O   . HOH N 5 .   ? 12.257  7.925   -16.468 1   42.539 ? 934  HOH B O   1 
HETATM 9145 O  O   . HOH N 5 .   ? 30.576  -8.615  20.168  1   22.429 ? 935  HOH B O   1 
HETATM 9146 O  O   . HOH N 5 .   ? 32.645  -19.819 4.592   1   20.195 ? 936  HOH B O   1 
HETATM 9147 O  O   . HOH N 5 .   ? 17.242  11.195  -12.871 1   40.639 ? 937  HOH B O   1 
HETATM 9148 O  O   . HOH N 5 .   ? 21.027  -22.789 1.744   1   20.256 ? 938  HOH B O   1 
HETATM 9149 O  O   . HOH N 5 .   ? 17.27   -11.261 -4.741  1   23.019 ? 939  HOH B O   1 
HETATM 9150 O  O   . HOH N 5 .   ? 38.717  -7.542  -12.075 1   27.029 ? 940  HOH B O   1 
HETATM 9151 O  O   . HOH N 5 .   ? 24.113  -12.604 17.685  1   21.71  ? 941  HOH B O   1 
HETATM 9152 O  O   . HOH N 5 .   ? 28.213  -19.446 9.188   1   24.668 ? 942  HOH B O   1 
HETATM 9153 O  O   . HOH N 5 .   ? 5.994   -27.765 1.822   1   45.764 ? 943  HOH B O   1 
HETATM 9154 O  O   . HOH N 5 .   ? 14.699  -3.569  -17.611 1   30.282 ? 944  HOH B O   1 
HETATM 9155 O  O   . HOH N 5 .   ? 16.195  -19.908 -19.185 1   51.065 ? 945  HOH B O   1 
HETATM 9156 O  O   . HOH N 5 .   ? 34.798  -16.653 -2.721  1   22.2   ? 946  HOH B O   1 
HETATM 9157 O  O   . HOH N 5 .   ? 30.339  -20.325 6.048   1   25.103 ? 947  HOH B O   1 
HETATM 9158 O  O   . HOH N 5 .   ? 41.419  -18.84  3.231   1   29.824 ? 948  HOH B O   1 
HETATM 9159 O  O   . HOH N 5 .   ? 6.551   4.737   -14.516 1   29.03  ? 949  HOH B O   1 
HETATM 9160 O  O   . HOH N 5 .   ? 23.355  5.891   13.709  1   39.796 ? 950  HOH B O   1 
HETATM 9161 O  O   . HOH N 5 .   ? 23.138  -10.605 27.738  1   24.182 ? 951  HOH B O   1 
HETATM 9162 O  O   . HOH N 5 .   ? 14.592  -24.947 19.629  1   29.632 ? 952  HOH B O   1 
HETATM 9163 O  O   . HOH N 5 .   ? 19.189  -18.107 29.393  1   29.384 ? 953  HOH B O   1 
HETATM 9164 O  O   . HOH N 5 .   ? 0.397   -12.53  -5.475  1   33.421 ? 954  HOH B O   1 
HETATM 9165 O  O   . HOH N 5 .   ? 39.607  -26.722 -2.856  1   34.866 ? 955  HOH B O   1 
HETATM 9166 O  O   . HOH N 5 .   ? -10.699 -4.357  -2.743  1   41.183 ? 956  HOH B O   1 
HETATM 9167 O  O   . HOH N 5 .   ? 34.051  7.016   -15.267 1   57.189 ? 957  HOH B O   1 
HETATM 9168 O  O   . HOH N 5 .   ? 11.06   12.328  4.681   1   36.453 ? 958  HOH B O   1 
HETATM 9169 O  O   . HOH N 5 .   ? 27.357  -3.768  -27.285 1   31.442 ? 959  HOH B O   1 
HETATM 9170 O  O   . HOH N 5 .   ? -1.757  -11.187 -4.04   1   26.863 ? 960  HOH B O   1 
HETATM 9171 O  O   . HOH N 5 .   ? -5.886  -16.679 19.011  1   25.014 ? 961  HOH B O   1 
HETATM 9172 O  O   . HOH N 5 .   ? 15.067  -9.657  -3.441  1   36.227 ? 962  HOH B O   1 
HETATM 9173 O  O   . HOH N 5 .   ? 33.352  -17.294 5.306   1   19.35  ? 963  HOH B O   1 
HETATM 9174 O  O   . HOH N 5 .   ? -12.445 -25.572 17.729  1   35.287 ? 964  HOH B O   1 
HETATM 9175 O  O   . HOH N 5 .   ? 29.97   13.78   3.317   1   35.943 ? 965  HOH B O   1 
HETATM 9176 O  O   . HOH N 5 .   ? 7.038   -9.153  -7.771  1   37.727 ? 966  HOH B O   1 
HETATM 9177 O  O   . HOH N 5 .   ? 49.073  3.917   3.13    1   43.046 ? 967  HOH B O   1 
HETATM 9178 O  O   . HOH N 5 .   ? 33.987  12.012  5.715   1   41.325 ? 968  HOH B O   1 
HETATM 9179 O  O   . HOH N 5 .   ? 14.601  3.341   4.737   1   23.359 ? 969  HOH B O   1 
HETATM 9180 O  O   . HOH N 5 .   ? 10.818  11.558  -13.086 1   50.306 ? 970  HOH B O   1 
HETATM 9181 O  O   . HOH N 5 .   ? 21.251  0.188   20.95   1   35.021 ? 971  HOH B O   1 
HETATM 9182 O  O   . HOH N 5 .   ? 16.65   -25.962 27.84   1   49.042 ? 972  HOH B O   1 
HETATM 9183 O  O   . HOH N 5 .   ? 5.677   -22.321 17.232  1   37.477 ? 973  HOH B O   1 
HETATM 9184 O  O   . HOH N 5 .   ? 46.189  1.723   -2.734  1   46.314 ? 974  HOH B O   1 
HETATM 9185 O  O   . HOH N 5 .   ? 37.969  -8.578  -16.973 1   31.021 ? 975  HOH B O   1 
HETATM 9186 O  O   . HOH N 5 .   ? 18.952  -28.872 10.516  1   34.505 ? 976  HOH B O   1 
HETATM 9187 O  O   . HOH N 5 .   ? 19.072  14.04   -2.442  1   51.477 ? 977  HOH B O   1 
HETATM 9188 O  O   . HOH N 5 .   ? -30.988 -13.963 34.706  1   42.062 ? 978  HOH B O   1 
HETATM 9189 O  O   . HOH N 5 .   ? 11.128  -14.723 -9.077  1   46.624 ? 979  HOH B O   1 
HETATM 9190 O  O   . HOH N 5 .   ? -3.923  -27.108 8.368   1   44.621 ? 980  HOH B O   1 
HETATM 9191 O  O   . HOH N 5 .   ? 26.134  -26.55  -14.372 1   26.698 ? 981  HOH B O   1 
HETATM 9192 O  O   . HOH N 5 .   ? 28.576  6.466   2.778   1   32.936 ? 982  HOH B O   1 
HETATM 9193 O  O   . HOH N 5 .   ? 11.669  -21.557 16.462  1   27.25  ? 983  HOH B O   1 
HETATM 9194 O  O   . HOH N 5 .   ? 5.059   10.529  -10.018 1   39.249 ? 984  HOH B O   1 
HETATM 9195 O  O   . HOH N 5 .   ? -22.869 -19.459 29.042  1   32.18  ? 985  HOH B O   1 
HETATM 9196 O  O   . HOH N 5 .   ? 19.853  -32.345 -4.663  1   37.063 ? 986  HOH B O   1 
HETATM 9197 O  O   . HOH N 5 .   ? 43.503  -14.365 3.128   1   25.146 ? 987  HOH B O   1 
HETATM 9198 O  O   . HOH N 5 .   ? 32.007  -19.196 13.413  1   25.521 ? 988  HOH B O   1 
HETATM 9199 O  O   . HOH N 5 .   ? 40.622  -9.335  -17.571 1   46.63  ? 989  HOH B O   1 
HETATM 9200 O  O   . HOH N 5 .   ? 24.324  8.084   -18.552 1   37.895 ? 990  HOH B O   1 
HETATM 9201 O  O   . HOH N 5 .   ? 30.127  -30.574 1.471   1   32.158 ? 991  HOH B O   1 
HETATM 9202 O  O   . HOH N 5 .   ? -14.026 -26.572 19.981  1   32.58  ? 992  HOH B O   1 
HETATM 9203 O  O   . HOH N 5 .   ? 2.135   6.211   5.965   1   25.937 ? 993  HOH B O   1 
HETATM 9204 O  O   . HOH N 5 .   ? 39.923  -3.996  10.577  1   33.596 ? 994  HOH B O   1 
HETATM 9205 O  O   . HOH N 5 .   ? 24.422  -10.435 21.008  1   22.63  ? 995  HOH B O   1 
HETATM 9206 O  O   . HOH N 5 .   ? -0.978  0.151   -13.303 1   35.628 ? 996  HOH B O   1 
HETATM 9207 O  O   . HOH N 5 .   ? 5.849   -15.916 -14.687 1   41.338 ? 997  HOH B O   1 
HETATM 9208 O  O   . HOH N 5 .   ? 41.185  -16.337 18.04   1   36.89  ? 998  HOH B O   1 
HETATM 9209 O  O   . HOH N 5 .   ? -2.65   -2.695  14.871  1   21.648 ? 999  HOH B O   1 
HETATM 9210 O  O   . HOH N 5 .   ? 34.531  -14.017 -3.733  1   24.994 ? 1000 HOH B O   1 
HETATM 9211 O  O   . HOH N 5 .   ? 3.689   10.949  -2.914  1   30.829 ? 1001 HOH B O   1 
HETATM 9212 O  O   . HOH N 5 .   ? 2.702   -0.273  -18.574 1   47.297 ? 1002 HOH B O   1 
HETATM 9213 O  O   . HOH N 5 .   ? 7.893   -23.187 18.951  1   47.294 ? 1003 HOH B O   1 
HETATM 9214 O  O   . HOH N 5 .   ? 6.138   -15.247 16.91   1   21.751 ? 1004 HOH B O   1 
HETATM 9215 O  O   . HOH N 5 .   ? 22.157  -0.698  -23.055 1   47.987 ? 1005 HOH B O   1 
HETATM 9216 O  O   . HOH N 5 .   ? 17.928  5.599   17.33   1   37.595 ? 1006 HOH B O   1 
HETATM 9217 O  O   . HOH N 5 .   ? 38.791  2.576   -10.867 1   30.989 ? 1007 HOH B O   1 
HETATM 9218 O  O   . HOH N 5 .   ? 13.585  -14.289 -7.417  1   27.007 ? 1008 HOH B O   1 
HETATM 9219 O  O   . HOH N 5 .   ? 18.691  13.632  -5.428  1   46.304 ? 1009 HOH B O   1 
HETATM 9220 O  O   . HOH N 5 .   ? 15.283  1.876   13.39   1   38.333 ? 1010 HOH B O   1 
HETATM 9221 O  O   . HOH N 5 .   ? -4.933  -19.923 11.892  1   50.319 ? 1011 HOH B O   1 
HETATM 9222 O  O   . HOH N 5 .   ? 37.549  -14.683 22.617  1   35.778 ? 1012 HOH B O   1 
HETATM 9223 O  O   . HOH N 5 .   ? 32.201  -26.768 1.218   1   39.877 ? 1013 HOH B O   1 
HETATM 9224 O  O   . HOH N 5 .   ? 2.804   -7.102  -19.572 1   36.194 ? 1014 HOH B O   1 
HETATM 9225 O  O   . HOH N 5 .   ? -19.212 -25.589 27.364  1   55.368 ? 1015 HOH B O   1 
HETATM 9226 O  O   . HOH N 5 .   ? 5.527   -7.22   -20.012 1   51.97  ? 1016 HOH B O   1 
HETATM 9227 O  O   . HOH N 5 .   ? -0.938  -18.24  17.294  1   31.017 ? 1017 HOH B O   1 
HETATM 9228 O  O   . HOH N 5 .   ? -10.153 -2.533  4.144   1   34.031 ? 1018 HOH B O   1 
HETATM 9229 O  O   . HOH N 5 .   ? 35.802  -6.572  -27.783 1   47.328 ? 1019 HOH B O   1 
HETATM 9230 O  O   . HOH N 5 .   ? 20.606  -5.106  15.79   1   30.067 ? 1020 HOH B O   1 
HETATM 9231 O  O   . HOH N 5 .   ? -0.768  -26.572 0.648   1   34.739 ? 1021 HOH B O   1 
HETATM 9232 O  O   . HOH N 5 .   ? 29.163  -30.345 -6.6    1   35.938 ? 1022 HOH B O   1 
HETATM 9233 O  O   . HOH N 5 .   ? 7.936   -25.787 -6.185  1   31.974 ? 1023 HOH B O   1 
HETATM 9234 O  O   . HOH N 5 .   ? 41.269  -19.116 21.934  1   50.935 ? 1024 HOH B O   1 
HETATM 9235 O  O   . HOH N 5 .   ? 15.395  1.038   3.356   1   23.864 ? 1025 HOH B O   1 
HETATM 9236 O  O   . HOH N 5 .   ? 17.812  16.19   -4.849  1   38.668 ? 1026 HOH B O   1 
HETATM 9237 O  O   . HOH N 5 .   ? 39.382  -20.372 9.352   1   23.762 ? 1027 HOH B O   1 
HETATM 9238 O  O   . HOH N 5 .   ? 1.996   6.221   17.19   1   38.533 ? 1028 HOH B O   1 
HETATM 9239 O  O   . HOH N 5 .   ? 40.137  -1.879  -21.746 1   37.928 ? 1029 HOH B O   1 
HETATM 9240 O  O   . HOH N 5 .   ? 17.895  1.11    4.634   1   25.629 ? 1030 HOH B O   1 
HETATM 9241 O  O   . HOH N 5 .   ? 33.169  6.827   -10.254 1   44.537 ? 1031 HOH B O   1 
HETATM 9242 O  O   . HOH N 5 .   ? 19.265  -3.398  -25.594 1   41.099 ? 1032 HOH B O   1 
HETATM 9243 O  O   . HOH N 5 .   ? -0.83   8.946   0.012   1   36.946 ? 1033 HOH B O   1 
HETATM 9244 O  O   . HOH N 5 .   ? -6.505  -21.627 13.369  1   40.307 ? 1034 HOH B O   1 
HETATM 9245 O  O   . HOH N 5 .   ? 11.308  15.103  6.586   1   57.968 ? 1035 HOH B O   1 
HETATM 9246 O  O   . HOH N 5 .   ? 9.22    -23.376 -6      1   25.631 ? 1036 HOH B O   1 
HETATM 9247 O  O   . HOH N 5 .   ? 10.493  -19.835 20.391  1   42.008 ? 1037 HOH B O   1 
HETATM 9248 O  O   . HOH N 5 .   ? 6.94    -23.06  -2.907  1   28.1   ? 1038 HOH B O   1 
HETATM 9249 O  O   . HOH N 5 .   ? 21.824  -18.138 3.007   1   19.391 ? 1039 HOH B O   1 
HETATM 9250 O  O   . HOH N 5 .   ? 39.005  -4.385  15.381  1   50.252 ? 1040 HOH B O   1 
HETATM 9251 O  O   . HOH N 5 .   ? -3.147  8.342   1.121   1   35.499 ? 1041 HOH B O   1 
HETATM 9252 O  O   . HOH N 5 .   ? 32.124  4.167   -21.836 1   35.322 ? 1042 HOH B O   1 
HETATM 9253 O  O   . HOH N 5 .   ? 15.706  2.958   16.087  1   35.423 ? 1043 HOH B O   1 
HETATM 9254 O  O   . HOH N 5 .   ? 17.239  -28.952 6.952   1   41.514 ? 1044 HOH B O   1 
HETATM 9255 O  O   . HOH N 5 .   ? 42.026  -7.097  2.184   1   27.272 ? 1045 HOH B O   1 
HETATM 9256 O  O   . HOH N 5 .   ? 28.563  5.905   -15.794 1   48.657 ? 1046 HOH B O   1 
HETATM 9257 O  O   . HOH N 5 .   ? 11.899  -5.437  15.05   1   30.752 ? 1047 HOH B O   1 
HETATM 9258 O  O   . HOH N 5 .   ? 37.19   -20.521 -11.82  1   31.079 ? 1048 HOH B O   1 
HETATM 9259 O  O   . HOH N 5 .   ? -26.701 -20.703 37.407  1   60.179 ? 1049 HOH B O   1 
HETATM 9260 O  O   . HOH N 5 .   ? 44.159  -0.451  1.366   1   27.494 ? 1050 HOH B O   1 
HETATM 9261 O  O   . HOH N 5 .   ? 25.579  2.197   6.169   1   43.936 ? 1051 HOH B O   1 
HETATM 9262 O  O   . HOH N 5 .   ? 42.91   -12.995 -10.342 1   51.63  ? 1052 HOH B O   1 
HETATM 9263 O  O   . HOH N 5 .   ? 13.4    -12.625 -22.362 1   29.227 ? 1053 HOH B O   1 
HETATM 9264 O  O   . HOH N 5 .   ? -2.258  -0.124  15.984  1   55.593 ? 1054 HOH B O   1 
HETATM 9265 O  O   . HOH N 5 .   ? 27.824  7.487   -13.457 1   39.84  ? 1055 HOH B O   1 
HETATM 9266 O  O   . HOH N 5 .   ? 41.181  -19.409 17.107  1   50.714 ? 1056 HOH B O   1 
HETATM 9267 O  O   . HOH N 5 .   ? 19.955  -14.773 21.537  1   18.785 ? 1057 HOH B O   1 
HETATM 9268 O  O   . HOH N 5 .   ? -23.692 -26.062 28.952  1   36.251 ? 1058 HOH B O   1 
HETATM 9269 O  O   . HOH N 5 .   ? 6.76    11.572  -11.968 1   49.636 ? 1059 HOH B O   1 
HETATM 9270 O  O   . HOH N 5 .   ? -19.872 -24.548 23.002  1   34.807 ? 1060 HOH B O   1 
HETATM 9271 O  O   . HOH N 5 .   ? 23.343  -24.703 27.334  1   50.596 ? 1061 HOH B O   1 
HETATM 9272 O  O   . HOH N 5 .   ? 33.869  -6.985  7.488   1   21.605 ? 1062 HOH B O   1 
HETATM 9273 O  O   . HOH N 5 .   ? -3.538  -24.05  1.168   1   33.946 ? 1063 HOH B O   1 
HETATM 9274 O  O   . HOH N 5 .   ? 35.284  -27.216 -14.239 1   29.146 ? 1064 HOH B O   1 
HETATM 9275 O  O   . HOH N 5 .   ? 15.641  -0.496  -23.405 1   40.631 ? 1065 HOH B O   1 
HETATM 9276 O  O   . HOH N 5 .   ? 8.648   -16.313 -18.065 1   45.014 ? 1066 HOH B O   1 
HETATM 9277 O  O   . HOH N 5 .   ? 45.422  -3.19   -2.949  1   41.445 ? 1067 HOH B O   1 
HETATM 9278 O  O   . HOH N 5 .   ? 14.795  -1.766  3.255   1   22.148 ? 1068 HOH B O   1 
HETATM 9279 O  O   . HOH N 5 .   ? -9.409  -26.95  25.631  1   35.361 ? 1069 HOH B O   1 
HETATM 9280 O  O   . HOH N 5 .   ? 24.546  -28.572 6.29    1   20.988 ? 1070 HOH B O   1 
HETATM 9281 O  O   . HOH N 5 .   ? 7.69    -19.132 -4.92   1   37.432 ? 1071 HOH B O   1 
HETATM 9282 O  O   . HOH N 5 .   ? 44.237  -8.531  1.377   1   41.732 ? 1072 HOH B O   1 
HETATM 9283 O  O   . HOH N 5 .   ? 45.915  -13.711 4.855   1   27.249 ? 1073 HOH B O   1 
HETATM 9284 O  O   . HOH N 5 .   ? -25.43  -25.494 31.584  1   29.819 ? 1074 HOH B O   1 
HETATM 9285 O  O   . HOH N 5 .   ? 7.476   -14.014 -18.046 1   47.546 ? 1075 HOH B O   1 
HETATM 9286 O  O   . HOH N 5 .   ? 24.224  11.379  -4.923  1   41.978 ? 1076 HOH B O   1 
HETATM 9287 O  O   . HOH N 5 .   ? 2.263   -24.344 11.023  1   39.362 ? 1077 HOH B O   1 
HETATM 9288 O  O   . HOH N 5 .   ? 34.836  5.085   -11.08  1   51.444 ? 1078 HOH B O   1 
HETATM 9289 O  O   . HOH N 5 .   ? 41.302  -4.718  0.936   1   33.348 ? 1079 HOH B O   1 
HETATM 9290 O  O   . HOH N 5 .   ? 9.318   5.111   13.589  1   37.669 ? 1080 HOH B O   1 
HETATM 9291 O  O   . HOH N 5 .   ? 37.953  -14.398 -17.463 1   31.318 ? 1081 HOH B O   1 
HETATM 9292 O  O   . HOH N 5 .   ? 7.639   13.621  -4.096  1   34.048 ? 1082 HOH B O   1 
HETATM 9293 O  O   . HOH N 5 .   ? 27.333  -16.565 -0.517  1   20.148 ? 1083 HOH B O   1 
HETATM 9294 O  O   . HOH N 5 .   ? 26.472  5.873   0.815   1   27.698 ? 1084 HOH B O   1 
HETATM 9295 O  O   . HOH N 5 .   ? 8.608   10.159  -16.172 1   38.328 ? 1085 HOH B O   1 
HETATM 9296 O  O   . HOH N 5 .   ? 31.548  9.991   -5.129  1   37.957 ? 1086 HOH B O   1 
HETATM 9297 O  O   . HOH N 5 .   ? -8.818  -13.632 6.428   1   49.714 ? 1087 HOH B O   1 
HETATM 9298 O  O   . HOH N 5 .   ? 14.073  3.344   11.462  1   51.12  ? 1088 HOH B O   1 
HETATM 9299 O  O   . HOH N 5 .   ? 15.652  6.372   28.091  1   60.162 ? 1089 HOH B O   1 
HETATM 9300 O  O   . HOH N 5 .   ? 8.497   8.481   19.109  1   49.073 ? 1090 HOH B O   1 
HETATM 9301 O  O   . HOH N 5 .   ? 16.955  -27.127 -15.279 1   37.22  ? 1091 HOH B O   1 
HETATM 9302 O  O   . HOH N 5 .   ? -11.659 -3.215  10.798  1   39.424 ? 1092 HOH B O   1 
HETATM 9303 O  O   . HOH N 5 .   ? -5.124  -12.377 7.171   1   30.89  ? 1093 HOH B O   1 
HETATM 9304 O  O   . HOH N 5 .   ? 28.500  -2.372  -29.229 1   40.647 ? 1094 HOH B O   1 
HETATM 9305 O  O   . HOH N 5 .   ? 44.19   -5.381  14.622  1   44.89  ? 1095 HOH B O   1 
HETATM 9306 O  O   . HOH N 5 .   ? 9.405   -15.705 -7.341  1   37.752 ? 1096 HOH B O   1 
HETATM 9307 O  O   . HOH N 5 .   ? 36.821  -27.107 6.383   1   59.062 ? 1097 HOH B O   1 
HETATM 9308 O  O   . HOH N 5 .   ? 36.248  0.564   -23.077 1   46.614 ? 1098 HOH B O   1 
HETATM 9309 O  O   . HOH N 5 .   ? 0.539   -19.86  13.23   1   37.272 ? 1099 HOH B O   1 
HETATM 9310 O  O   . HOH N 5 .   ? 25.858  -30.231 -12.695 1   51.554 ? 1100 HOH B O   1 
HETATM 9311 O  O   . HOH N 5 .   ? 17.966  -22.464 -18.727 1   48.616 ? 1101 HOH B O   1 
HETATM 9312 O  O   . HOH N 5 .   ? 22.309  -29.594 7.673   1   29.919 ? 1102 HOH B O   1 
HETATM 9313 O  O   . HOH N 5 .   ? 24.964  4.998   11.764  1   38.969 ? 1103 HOH B O   1 
HETATM 9314 O  O   . HOH N 5 .   ? -4.802  14.330  -4.147  1   39.216 ? 1104 HOH B O   1 
HETATM 9315 O  O   . HOH N 5 .   ? 3.747   14.495  5.304   1   39.169 ? 1105 HOH B O   1 
HETATM 9316 O  O   . HOH N 5 .   ? 30.345  -16.17  -22.242 1   32.874 ? 1106 HOH B O   1 
HETATM 9317 O  O   . HOH N 5 .   ? 23.745  -23.732 24.343  1   33.529 ? 1107 HOH B O   1 
HETATM 9318 O  O   . HOH N 5 .   ? 10.893  2.878   22.19   1   35.807 ? 1108 HOH B O   1 
HETATM 9319 O  O   . HOH N 5 .   ? -1.536  8.301   -12.164 1   62.382 ? 1109 HOH B O   1 
HETATM 9320 O  O   . HOH N 5 .   ? 35.699  7.589   6.742   1   53.04  ? 1110 HOH B O   1 
HETATM 9321 O  O   . HOH N 5 .   ? -3.485  7.226   14.656  1   52.384 ? 1111 HOH B O   1 
HETATM 9322 O  O   . HOH N 5 .   ? 30.191  13.585  -3.461  1   55.684 ? 1112 HOH B O   1 
HETATM 9323 O  O   . HOH N 5 .   ? 15.121  5.296   11.768  1   53.886 ? 1113 HOH B O   1 
HETATM 9324 O  O   . HOH N 5 .   ? 16.892  -7.745  -3.768  1   26.019 ? 1114 HOH B O   1 
HETATM 9325 O  O   . HOH N 5 .   ? -10.523 4.374   1.796   1   51.668 ? 1115 HOH B O   1 
HETATM 9326 O  O   . HOH N 5 .   ? 30.826  -6.687  17.965  1   34.039 ? 1116 HOH B O   1 
HETATM 9327 O  O   . HOH N 5 .   ? 7.629   -16.796 -11.68  1   51.854 ? 1117 HOH B O   1 
HETATM 9328 O  O   . HOH N 5 .   ? 5.678   12.714  -5.095  1   45.678 ? 1118 HOH B O   1 
HETATM 9329 O  O   . HOH N 5 .   ? 21.382  1.521   23.045  1   57.701 ? 1119 HOH B O   1 
HETATM 9330 O  O   . HOH N 5 .   ? 6.86    -16.467 19.275  1   37.303 ? 1120 HOH B O   1 
HETATM 9331 O  O   . HOH N 5 .   ? -16.214 -27.524 18.6    1   50.101 ? 1121 HOH B O   1 
HETATM 9332 O  O   . HOH N 5 .   ? 17.688  -15.66  -25.375 1   67.609 ? 1122 HOH B O   1 
HETATM 9333 O  O   . HOH N 5 .   ? 13.061  -27.091 18.023  1   55.99  ? 1123 HOH B O   1 
HETATM 9334 O  O   . HOH N 5 .   ? 17.848  -11.380 -33.762 1   51.852 ? 1124 HOH B O   1 
HETATM 9335 O  O   . HOH N 5 .   ? 42.299  -4.735  18.511  1   42.167 ? 1125 HOH B O   1 
HETATM 9336 O  O   . HOH N 5 .   ? 36.82   -27.141 -10.222 1   36.662 ? 1126 HOH B O   1 
HETATM 9337 O  O   . HOH N 5 .   ? 27.635  -19.61  -23.147 1   44.883 ? 1127 HOH B O   1 
HETATM 9338 O  O   . HOH N 5 .   ? 37.472  -24.446 -8.895  1   37.144 ? 1128 HOH B O   1 
HETATM 9339 O  O   . HOH N 5 .   ? 13.373  -14.243 -4.989  1   47.95  ? 1129 HOH B O   1 
HETATM 9340 O  O   . HOH N 5 .   ? -21.215 -24.347 36.695  1   32.581 ? 1130 HOH B O   1 
HETATM 9341 O  O   . HOH N 5 .   ? 7.407   -16.68  -3.809  1   39.081 ? 1131 HOH B O   1 
HETATM 9342 O  O   . HOH N 5 .   ? 16.941  7.122   12.357  1   50.817 ? 1132 HOH B O   1 
HETATM 9343 O  O   . HOH N 5 .   ? 2.902   12.677  -1.03   1   40.453 ? 1133 HOH B O   1 
HETATM 9344 O  O   . HOH N 5 .   ? 42.095  -20.939 4.88    1   30.788 ? 1134 HOH B O   1 
HETATM 9345 O  O   . HOH N 5 .   ? 18.334  -29.214 -15.396 1   40.042 ? 1135 HOH B O   1 
HETATM 9346 O  O   . HOH N 5 .   ? -23.377 -21.858 25.909  1   49.135 ? 1136 HOH B O   1 
HETATM 9347 O  O   . HOH N 5 .   ? 38.949  -2.867  13.332  1   41.32  ? 1137 HOH B O   1 
HETATM 9348 O  O   . HOH N 5 .   ? 27.464  3.9     7.78    1   36.892 ? 1138 HOH B O   1 
HETATM 9349 O  O   . HOH N 5 .   ? 15.987  -26.483 -17.668 1   47.783 ? 1139 HOH B O   1 
HETATM 9350 O  O   . HOH N 5 .   ? 28.784  -3.099  -25.047 1   31.691 ? 1140 HOH B O   1 
HETATM 9351 O  O   . HOH N 5 .   ? 42.036  -20.038 0.519   1   35.874 ? 1141 HOH B O   1 
HETATM 9352 O  O   . HOH N 5 .   ? -9.73   -1.165  -7.276  1   57.193 ? 1142 HOH B O   1 
HETATM 9353 O  O   . HOH N 5 .   ? 27.475  6.537   7.599   1   50.936 ? 1143 HOH B O   1 
HETATM 9354 O  O   . HOH N 5 .   ? 28.353  -23.96  22.6    1   45.539 ? 1144 HOH B O   1 
HETATM 9355 O  O   . HOH N 5 .   ? 7.955   -23.632 -9.897  1   45.072 ? 1145 HOH B O   1 
HETATM 9356 O  O   . HOH N 5 .   ? 43.423  -17.1   3.005   1   30.922 ? 1146 HOH B O   1 
HETATM 9357 O  O   . HOH N 5 .   ? 25.195  5.827   -21.521 1   60.174 ? 1147 HOH B O   1 
HETATM 9358 O  O   . HOH N 5 .   ? 34.624  2.77    -22.57  1   63.589 ? 1148 HOH B O   1 
HETATM 9359 O  O   . HOH N 5 .   ? 32.292  -4.587  -23.175 1   34.055 ? 1149 HOH B O   1 
HETATM 9360 O  O   . HOH N 5 .   ? -5.038  5.364   -5.843  1   35.267 ? 1150 HOH B O   1 
HETATM 9361 O  O   . HOH N 5 .   ? 12.407  -26.727 -16.932 1   47.818 ? 1151 HOH B O   1 
HETATM 9362 O  O   . HOH N 5 .   ? -4.527  -15.488 6.912   1   32.009 ? 1152 HOH B O   1 
HETATM 9363 O  O   . HOH N 5 .   ? 48.288  -14.76  9.4     1   46.08  ? 1153 HOH B O   1 
HETATM 9364 O  O   . HOH N 5 .   ? 5.036   -25.565 5.395   1   30.109 ? 1154 HOH B O   1 
HETATM 9365 O  O   . HOH N 5 .   ? 42.543  -4.268  11.13   1   55.677 ? 1155 HOH B O   1 
HETATM 9366 O  O   . HOH N 5 .   ? 41.291  -1.726  -13.887 1   55.391 ? 1156 HOH B O   1 
HETATM 9367 O  O   . HOH N 5 .   ? 27.8    -32.028 1.715   1   28.197 ? 1157 HOH B O   1 
HETATM 9368 O  O   . HOH N 5 .   ? 25.291  -25.445 -22.432 1   54.936 ? 1158 HOH B O   1 
HETATM 9369 O  O   . HOH N 5 .   ? 12.698  -15.156 -22.518 1   53.82  ? 1159 HOH B O   1 
HETATM 9370 O  O   . HOH N 5 .   ? 15.436  -16.292 -24.317 1   59.676 ? 1160 HOH B O   1 
# 
