data_9G88
# 
_entry.id   9G88 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9G88         pdb_00009g88 10.2210/pdb9g88/pdb 
WWPDB D_1292140526 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9G88 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 jacek.plewka@uj.edu.pl       Jacek     Plewka         ? 'principal investigator/group leader' 0000-0002-0307-0907 
3 lukas.schober@tugraz.at      Lukas     Schober        ? 'principal investigator/group leader' 0009-0001-4003-0218 
4 k.magiera@uj.edu.pl          Katarzyna Magiera-Mularz ? 'principal investigator/group leader' 0000-0002-4826-6380 
5 florian.rudroff@tuwien.ac.at Florian   Rudroff        ? 'principal investigator/group leader' 0000-0002-6680-8200 
6 margit.winkler@tugraz.at     Margit    Winkler        ? 'principal investigator/group leader' 0000-0002-0754-9704 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Plewka, J.'         1 0000-0002-0307-0907 
'Schober, L.'        2 0009-0001-4003-0218 
'Magiera-Mularz, K.' 3 0000-0002-4826-6380 
'Rudroff, F.'        4 0000-0002-6680-8200 
'Winkler, M.'        5 0000-0002-0754-9704 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'structure of carotenoid cleavage oxygenase from Moesziomyces aphidis in apo and product bound forms' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.5c00456 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Schober, L.'        1 ? 
primary 'Plewka, J.'         2 ? 
primary 'Magiera-Mularz, K.' 3 ? 
primary 'Rudroff, F.'        4 ? 
primary 'Winkler, M.'        5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Lignostilbene dioxygenase' 62905.562 2    ? ? ? 'Aromatic dioxygenase' 
2 non-polymer syn 'ACETATE ION'               59.044    2    ? ? ? ?                      
3 non-polymer syn 'FE (II) ION'               55.845    2    ? ? ? ?                      
4 water       nat water                       18.015    1320 ? ? ? ?                      
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Carotenoid cleavage oxygenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MWSHPQFEKAPTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFY
RIMPDYAQPPTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVES
TANTNVVMHAGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDP
SGKVVRDLWLEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNG
MPIHTASGFEDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEF
PQIDNRFMGVEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLA
IVDRLDLNRSEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ACETATE ION' ACT 
3 'FE (II) ION' FE2 
4 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   TRP n 
1 3   SER n 
1 4   HIS n 
1 5   PRO n 
1 6   GLN n 
1 7   PHE n 
1 8   GLU n 
1 9   LYS n 
1 10  ALA n 
1 11  PRO n 
1 12  THR n 
1 13  ALA n 
1 14  THR n 
1 15  GLN n 
1 16  GLU n 
1 17  PRO n 
1 18  VAL n 
1 19  PRO n 
1 20  VAL n 
1 21  PRO n 
1 22  VAL n 
1 23  THR n 
1 24  SER n 
1 25  LYS n 
1 26  ALA n 
1 27  ALA n 
1 28  PRO n 
1 29  SER n 
1 30  HIS n 
1 31  GLY n 
1 32  TYR n 
1 33  VAL n 
1 34  HIS n 
1 35  PRO n 
1 36  THR n 
1 37  ASP n 
1 38  ILE n 
1 39  LEU n 
1 40  PRO n 
1 41  SER n 
1 42  GLY n 
1 43  TRP n 
1 44  PRO n 
1 45  THR n 
1 46  ALA n 
1 47  THR n 
1 48  ASP n 
1 49  LEU n 
1 50  SER n 
1 51  GLY n 
1 52  GLY n 
1 53  ALA n 
1 54  GLN n 
1 55  PRO n 
1 56  ARG n 
1 57  ARG n 
1 58  PHE n 
1 59  GLU n 
1 60  GLY n 
1 61  THR n 
1 62  ILE n 
1 63  PHE n 
1 64  ASP n 
1 65  VAL n 
1 66  MET n 
1 67  THR n 
1 68  ARG n 
1 69  GLY n 
1 70  THR n 
1 71  ILE n 
1 72  PRO n 
1 73  LYS n 
1 74  GLU n 
1 75  LEU n 
1 76  HIS n 
1 77  GLY n 
1 78  THR n 
1 79  PHE n 
1 80  TYR n 
1 81  ARG n 
1 82  ILE n 
1 83  MET n 
1 84  PRO n 
1 85  ASP n 
1 86  TYR n 
1 87  ALA n 
1 88  GLN n 
1 89  PRO n 
1 90  PRO n 
1 91  THR n 
1 92  TYR n 
1 93  TYR n 
1 94  LYS n 
1 95  GLY n 
1 96  GLY n 
1 97  GLU n 
1 98  LEU n 
1 99  ASN n 
1 100 ALA n 
1 101 PRO n 
1 102 ILE n 
1 103 ASP n 
1 104 GLY n 
1 105 ASP n 
1 106 GLY n 
1 107 THR n 
1 108 VAL n 
1 109 ALA n 
1 110 ALA n 
1 111 PHE n 
1 112 ARG n 
1 113 PHE n 
1 114 LYS n 
1 115 ASP n 
1 116 GLY n 
1 117 LYS n 
1 118 VAL n 
1 119 ASP n 
1 120 TYR n 
1 121 ARG n 
1 122 GLN n 
1 123 ARG n 
1 124 PHE n 
1 125 VAL n 
1 126 GLU n 
1 127 THR n 
1 128 ASP n 
1 129 ARG n 
1 130 PHE n 
1 131 LYS n 
1 132 VAL n 
1 133 GLU n 
1 134 ARG n 
1 135 ARG n 
1 136 ALA n 
1 137 ARG n 
1 138 LYS n 
1 139 SER n 
1 140 MET n 
1 141 TYR n 
1 142 GLY n 
1 143 LEU n 
1 144 TYR n 
1 145 ARG n 
1 146 ASN n 
1 147 PRO n 
1 148 TYR n 
1 149 THR n 
1 150 HIS n 
1 151 HIS n 
1 152 PRO n 
1 153 CYS n 
1 154 VAL n 
1 155 ARG n 
1 156 GLN n 
1 157 THR n 
1 158 VAL n 
1 159 GLU n 
1 160 SER n 
1 161 THR n 
1 162 ALA n 
1 163 ASN n 
1 164 THR n 
1 165 ASN n 
1 166 VAL n 
1 167 VAL n 
1 168 MET n 
1 169 HIS n 
1 170 ALA n 
1 171 GLY n 
1 172 ARG n 
1 173 PHE n 
1 174 LEU n 
1 175 ALA n 
1 176 MET n 
1 177 LYS n 
1 178 GLU n 
1 179 ASN n 
1 180 GLY n 
1 181 ASN n 
1 182 ALA n 
1 183 TYR n 
1 184 GLU n 
1 185 MET n 
1 186 ASP n 
1 187 PRO n 
1 188 HIS n 
1 189 THR n 
1 190 LEU n 
1 191 LYS n 
1 192 THR n 
1 193 LEU n 
1 194 GLY n 
1 195 TYR n 
1 196 ASN n 
1 197 PRO n 
1 198 PHE n 
1 199 ASN n 
1 200 LEU n 
1 201 PRO n 
1 202 SER n 
1 203 LYS n 
1 204 THR n 
1 205 MET n 
1 206 THR n 
1 207 ALA n 
1 208 HIS n 
1 209 PRO n 
1 210 LYS n 
1 211 GLN n 
1 212 CYS n 
1 213 SER n 
1 214 VAL n 
1 215 THR n 
1 216 GLY n 
1 217 ASN n 
1 218 LEU n 
1 219 VAL n 
1 220 GLY n 
1 221 PHE n 
1 222 GLY n 
1 223 TYR n 
1 224 GLU n 
1 225 ALA n 
1 226 LYS n 
1 227 GLY n 
1 228 LEU n 
1 229 ALA n 
1 230 THR n 
1 231 LYS n 
1 232 ASP n 
1 233 VAL n 
1 234 TYR n 
1 235 TYR n 
1 236 PHE n 
1 237 GLU n 
1 238 VAL n 
1 239 ASP n 
1 240 PRO n 
1 241 SER n 
1 242 GLY n 
1 243 LYS n 
1 244 VAL n 
1 245 VAL n 
1 246 ARG n 
1 247 ASP n 
1 248 LEU n 
1 249 TRP n 
1 250 LEU n 
1 251 GLU n 
1 252 ALA n 
1 253 PRO n 
1 254 TRP n 
1 255 CYS n 
1 256 ALA n 
1 257 PHE n 
1 258 ILE n 
1 259 HIS n 
1 260 ASP n 
1 261 CYS n 
1 262 ALA n 
1 263 LEU n 
1 264 THR n 
1 265 PRO n 
1 266 ASN n 
1 267 TYR n 
1 268 LEU n 
1 269 VAL n 
1 270 LEU n 
1 271 MET n 
1 272 LEU n 
1 273 TRP n 
1 274 PRO n 
1 275 PHE n 
1 276 GLU n 
1 277 ALA n 
1 278 ASN n 
1 279 LEU n 
1 280 GLU n 
1 281 ARG n 
1 282 MET n 
1 283 LYS n 
1 284 ALA n 
1 285 GLY n 
1 286 GLY n 
1 287 HIS n 
1 288 HIS n 
1 289 TRP n 
1 290 ALA n 
1 291 TYR n 
1 292 ASP n 
1 293 TYR n 
1 294 THR n 
1 295 LYS n 
1 296 PRO n 
1 297 ILE n 
1 298 THR n 
1 299 TRP n 
1 300 ILE n 
1 301 THR n 
1 302 ILE n 
1 303 PRO n 
1 304 ARG n 
1 305 GLY n 
1 306 ALA n 
1 307 LYS n 
1 308 SER n 
1 309 LYS n 
1 310 ASP n 
1 311 GLU n 
1 312 VAL n 
1 313 LYS n 
1 314 TYR n 
1 315 TRP n 
1 316 HIS n 
1 317 TRP n 
1 318 LYS n 
1 319 ASN n 
1 320 GLY n 
1 321 MET n 
1 322 PRO n 
1 323 ILE n 
1 324 HIS n 
1 325 THR n 
1 326 ALA n 
1 327 SER n 
1 328 GLY n 
1 329 PHE n 
1 330 GLU n 
1 331 ASP n 
1 332 GLU n 
1 333 GLN n 
1 334 GLY n 
1 335 ARG n 
1 336 ILE n 
1 337 ILE n 
1 338 ILE n 
1 339 ASP n 
1 340 SER n 
1 341 SER n 
1 342 LEU n 
1 343 VAL n 
1 344 HIS n 
1 345 GLY n 
1 346 ASN n 
1 347 ALA n 
1 348 PHE n 
1 349 PRO n 
1 350 PHE n 
1 351 PHE n 
1 352 PRO n 
1 353 PRO n 
1 354 ASP n 
1 355 SER n 
1 356 ASP n 
1 357 GLU n 
1 358 GLN n 
1 359 LYS n 
1 360 LYS n 
1 361 LYS n 
1 362 GLN n 
1 363 GLU n 
1 364 ALA n 
1 365 ASP n 
1 366 GLY n 
1 367 THR n 
1 368 PRO n 
1 369 LYS n 
1 370 ALA n 
1 371 GLN n 
1 372 PHE n 
1 373 VAL n 
1 374 ARG n 
1 375 TRP n 
1 376 THR n 
1 377 ILE n 
1 378 ASP n 
1 379 PRO n 
1 380 ARG n 
1 381 LYS n 
1 382 ASP n 
1 383 ASN n 
1 384 ASN n 
1 385 GLU n 
1 386 GLN n 
1 387 LEU n 
1 388 PRO n 
1 389 ASP n 
1 390 PRO n 
1 391 GLU n 
1 392 VAL n 
1 393 ILE n 
1 394 LEU n 
1 395 ASP n 
1 396 THR n 
1 397 PRO n 
1 398 SER n 
1 399 GLU n 
1 400 PHE n 
1 401 PRO n 
1 402 GLN n 
1 403 ILE n 
1 404 ASP n 
1 405 ASN n 
1 406 ARG n 
1 407 PHE n 
1 408 MET n 
1 409 GLY n 
1 410 VAL n 
1 411 GLU n 
1 412 TYR n 
1 413 SER n 
1 414 SER n 
1 415 ALA n 
1 416 PHE n 
1 417 ILE n 
1 418 ASN n 
1 419 VAL n 
1 420 PHE n 
1 421 VAL n 
1 422 PRO n 
1 423 ASP n 
1 424 ARG n 
1 425 SER n 
1 426 ASP n 
1 427 GLY n 
1 428 ASN n 
1 429 LYS n 
1 430 ASN n 
1 431 VAL n 
1 432 PHE n 
1 433 GLN n 
1 434 GLY n 
1 435 LEU n 
1 436 ASN n 
1 437 GLY n 
1 438 LEU n 
1 439 ALA n 
1 440 HIS n 
1 441 TYR n 
1 442 LYS n 
1 443 ARG n 
1 444 LYS n 
1 445 GLU n 
1 446 GLY n 
1 447 THR n 
1 448 THR n 
1 449 GLU n 
1 450 TRP n 
1 451 TYR n 
1 452 TYR n 
1 453 ALA n 
1 454 GLY n 
1 455 ASP n 
1 456 ASN n 
1 457 CYS n 
1 458 LEU n 
1 459 ILE n 
1 460 GLN n 
1 461 GLU n 
1 462 PRO n 
1 463 VAL n 
1 464 PHE n 
1 465 SER n 
1 466 PRO n 
1 467 ARG n 
1 468 SER n 
1 469 LYS n 
1 470 ASP n 
1 471 ALA n 
1 472 PRO n 
1 473 GLU n 
1 474 GLY n 
1 475 ASP n 
1 476 GLY n 
1 477 PHE n 
1 478 VAL n 
1 479 LEU n 
1 480 ALA n 
1 481 ILE n 
1 482 VAL n 
1 483 ASP n 
1 484 ARG n 
1 485 LEU n 
1 486 ASP n 
1 487 LEU n 
1 488 ASN n 
1 489 ARG n 
1 490 SER n 
1 491 GLU n 
1 492 VAL n 
1 493 VAL n 
1 494 VAL n 
1 495 ILE n 
1 496 ASP n 
1 497 THR n 
1 498 ARG n 
1 499 ASP n 
1 500 PHE n 
1 501 THR n 
1 502 LYS n 
1 503 ALA n 
1 504 VAL n 
1 505 ALA n 
1 506 ALA n 
1 507 VAL n 
1 508 GLN n 
1 509 LEU n 
1 510 PRO n 
1 511 PHE n 
1 512 ALA n 
1 513 ILE n 
1 514 ARG n 
1 515 SER n 
1 516 GLY n 
1 517 ILE n 
1 518 HIS n 
1 519 GLY n 
1 520 GLN n 
1 521 TRP n 
1 522 ILE n 
1 523 PRO n 
1 524 GLY n 
1 525 GLU n 
1 526 VAL n 
1 527 THR n 
1 528 PRO n 
1 529 ASP n 
1 530 PHE n 
1 531 GLU n 
1 532 THR n 
1 533 LYS n 
1 534 GLY n 
1 535 LEU n 
1 536 VAL n 
1 537 ASP n 
1 538 LEU n 
1 539 PRO n 
1 540 LYS n 
1 541 GLU n 
1 542 GLU n 
1 543 HIS n 
1 544 TRP n 
1 545 ALA n 
1 546 PRO n 
1 547 LEU n 
1 548 SER n 
1 549 GLN n 
1 550 SER n 
1 551 PRO n 
1 552 TYR n 
1 553 ASP n 
1 554 PRO n 
1 555 ASP n 
1 556 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   556 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PaG_05861 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Moesziomyces aphidis' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     84754 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ACT non-polymer         . 'ACETATE ION'   ? 'C2 H3 O2 -1'    59.044  
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
FE2 non-polymer         . 'FE (II) ION'   ? 'Fe 2'           55.845  
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -7  ?   ?   ?   A . n 
A 1 2   TRP 2   -6  ?   ?   ?   A . n 
A 1 3   SER 3   -5  ?   ?   ?   A . n 
A 1 4   HIS 4   -4  ?   ?   ?   A . n 
A 1 5   PRO 5   -3  ?   ?   ?   A . n 
A 1 6   GLN 6   -2  ?   ?   ?   A . n 
A 1 7   PHE 7   -1  ?   ?   ?   A . n 
A 1 8   GLU 8   0   ?   ?   ?   A . n 
A 1 9   LYS 9   1   ?   ?   ?   A . n 
A 1 10  ALA 10  2   ?   ?   ?   A . n 
A 1 11  PRO 11  3   ?   ?   ?   A . n 
A 1 12  THR 12  4   ?   ?   ?   A . n 
A 1 13  ALA 13  5   ?   ?   ?   A . n 
A 1 14  THR 14  6   ?   ?   ?   A . n 
A 1 15  GLN 15  7   ?   ?   ?   A . n 
A 1 16  GLU 16  8   ?   ?   ?   A . n 
A 1 17  PRO 17  9   ?   ?   ?   A . n 
A 1 18  VAL 18  10  ?   ?   ?   A . n 
A 1 19  PRO 19  11  ?   ?   ?   A . n 
A 1 20  VAL 20  12  ?   ?   ?   A . n 
A 1 21  PRO 21  13  ?   ?   ?   A . n 
A 1 22  VAL 22  14  ?   ?   ?   A . n 
A 1 23  THR 23  15  ?   ?   ?   A . n 
A 1 24  SER 24  16  ?   ?   ?   A . n 
A 1 25  LYS 25  17  ?   ?   ?   A . n 
A 1 26  ALA 26  18  ?   ?   ?   A . n 
A 1 27  ALA 27  19  ?   ?   ?   A . n 
A 1 28  PRO 28  20  ?   ?   ?   A . n 
A 1 29  SER 29  21  ?   ?   ?   A . n 
A 1 30  HIS 30  22  ?   ?   ?   A . n 
A 1 31  GLY 31  23  ?   ?   ?   A . n 
A 1 32  TYR 32  24  32  TYR TYR A . n 
A 1 33  VAL 33  25  33  VAL VAL A . n 
A 1 34  HIS 34  26  34  HIS HIS A . n 
A 1 35  PRO 35  27  35  PRO PRO A . n 
A 1 36  THR 36  28  36  THR THR A . n 
A 1 37  ASP 37  29  37  ASP ASP A . n 
A 1 38  ILE 38  30  38  ILE ILE A . n 
A 1 39  LEU 39  31  39  LEU LEU A . n 
A 1 40  PRO 40  32  40  PRO PRO A . n 
A 1 41  SER 41  33  41  SER SER A . n 
A 1 42  GLY 42  34  42  GLY GLY A . n 
A 1 43  TRP 43  35  43  TRP TRP A . n 
A 1 44  PRO 44  36  44  PRO PRO A . n 
A 1 45  THR 45  37  45  THR THR A . n 
A 1 46  ALA 46  38  46  ALA ALA A . n 
A 1 47  THR 47  39  47  THR THR A . n 
A 1 48  ASP 48  40  48  ASP ASP A . n 
A 1 49  LEU 49  41  49  LEU LEU A . n 
A 1 50  SER 50  42  50  SER SER A . n 
A 1 51  GLY 51  43  51  GLY GLY A . n 
A 1 52  GLY 52  44  52  GLY GLY A . n 
A 1 53  ALA 53  45  53  ALA ALA A . n 
A 1 54  GLN 54  46  54  GLN GLN A . n 
A 1 55  PRO 55  47  55  PRO PRO A . n 
A 1 56  ARG 56  48  56  ARG ARG A . n 
A 1 57  ARG 57  49  57  ARG ARG A . n 
A 1 58  PHE 58  50  58  PHE PHE A . n 
A 1 59  GLU 59  51  59  GLU GLU A . n 
A 1 60  GLY 60  52  60  GLY GLY A . n 
A 1 61  THR 61  53  61  THR THR A . n 
A 1 62  ILE 62  54  62  ILE ILE A . n 
A 1 63  PHE 63  55  63  PHE PHE A . n 
A 1 64  ASP 64  56  64  ASP ASP A . n 
A 1 65  VAL 65  57  65  VAL VAL A . n 
A 1 66  MET 66  58  66  MET MET A . n 
A 1 67  THR 67  59  67  THR THR A . n 
A 1 68  ARG 68  60  68  ARG ARG A . n 
A 1 69  GLY 69  61  69  GLY GLY A . n 
A 1 70  THR 70  62  70  THR THR A . n 
A 1 71  ILE 71  63  71  ILE ILE A . n 
A 1 72  PRO 72  64  72  PRO PRO A . n 
A 1 73  LYS 73  65  73  LYS LYS A . n 
A 1 74  GLU 74  66  74  GLU GLU A . n 
A 1 75  LEU 75  67  75  LEU LEU A . n 
A 1 76  HIS 76  68  76  HIS HIS A . n 
A 1 77  GLY 77  69  77  GLY GLY A . n 
A 1 78  THR 78  70  78  THR THR A . n 
A 1 79  PHE 79  71  79  PHE PHE A . n 
A 1 80  TYR 80  72  80  TYR TYR A . n 
A 1 81  ARG 81  73  81  ARG ARG A . n 
A 1 82  ILE 82  74  82  ILE ILE A . n 
A 1 83  MET 83  75  83  MET MET A . n 
A 1 84  PRO 84  76  84  PRO PRO A . n 
A 1 85  ASP 85  77  85  ASP ASP A . n 
A 1 86  TYR 86  78  86  TYR TYR A . n 
A 1 87  ALA 87  79  87  ALA ALA A . n 
A 1 88  GLN 88  80  88  GLN GLN A . n 
A 1 89  PRO 89  81  89  PRO PRO A . n 
A 1 90  PRO 90  82  90  PRO PRO A . n 
A 1 91  THR 91  83  91  THR THR A . n 
A 1 92  TYR 92  84  92  TYR TYR A . n 
A 1 93  TYR 93  85  93  TYR TYR A . n 
A 1 94  LYS 94  86  94  LYS LYS A . n 
A 1 95  GLY 95  87  95  GLY GLY A . n 
A 1 96  GLY 96  88  96  GLY GLY A . n 
A 1 97  GLU 97  89  97  GLU GLU A . n 
A 1 98  LEU 98  90  98  LEU LEU A . n 
A 1 99  ASN 99  91  99  ASN ASN A . n 
A 1 100 ALA 100 92  100 ALA ALA A . n 
A 1 101 PRO 101 93  101 PRO PRO A . n 
A 1 102 ILE 102 94  102 ILE ILE A . n 
A 1 103 ASP 103 95  103 ASP ASP A . n 
A 1 104 GLY 104 96  104 GLY GLY A . n 
A 1 105 ASP 105 97  105 ASP ASP A . n 
A 1 106 GLY 106 98  106 GLY GLY A . n 
A 1 107 THR 107 99  107 THR THR A . n 
A 1 108 VAL 108 100 108 VAL VAL A . n 
A 1 109 ALA 109 101 109 ALA ALA A . n 
A 1 110 ALA 110 102 110 ALA ALA A . n 
A 1 111 PHE 111 103 111 PHE PHE A . n 
A 1 112 ARG 112 104 112 ARG ARG A . n 
A 1 113 PHE 113 105 113 PHE PHE A . n 
A 1 114 LYS 114 106 114 LYS LYS A . n 
A 1 115 ASP 115 107 115 ASP ASP A . n 
A 1 116 GLY 116 108 116 GLY GLY A . n 
A 1 117 LYS 117 109 117 LYS LYS A . n 
A 1 118 VAL 118 110 118 VAL VAL A . n 
A 1 119 ASP 119 111 119 ASP ASP A . n 
A 1 120 TYR 120 112 120 TYR TYR A . n 
A 1 121 ARG 121 113 121 ARG ARG A . n 
A 1 122 GLN 122 114 122 GLN GLN A . n 
A 1 123 ARG 123 115 123 ARG ARG A . n 
A 1 124 PHE 124 116 124 PHE PHE A . n 
A 1 125 VAL 125 117 125 VAL VAL A . n 
A 1 126 GLU 126 118 126 GLU GLU A . n 
A 1 127 THR 127 119 127 THR THR A . n 
A 1 128 ASP 128 120 128 ASP ASP A . n 
A 1 129 ARG 129 121 129 ARG ARG A . n 
A 1 130 PHE 130 122 130 PHE PHE A . n 
A 1 131 LYS 131 123 131 LYS LYS A . n 
A 1 132 VAL 132 124 132 VAL VAL A . n 
A 1 133 GLU 133 125 133 GLU GLU A . n 
A 1 134 ARG 134 126 134 ARG ARG A . n 
A 1 135 ARG 135 127 135 ARG ARG A . n 
A 1 136 ALA 136 128 136 ALA ALA A . n 
A 1 137 ARG 137 129 137 ARG ARG A . n 
A 1 138 LYS 138 130 138 LYS LYS A . n 
A 1 139 SER 139 131 139 SER SER A . n 
A 1 140 MET 140 132 140 MET MET A . n 
A 1 141 TYR 141 133 141 TYR TYR A . n 
A 1 142 GLY 142 134 142 GLY GLY A . n 
A 1 143 LEU 143 135 143 LEU LEU A . n 
A 1 144 TYR 144 136 144 TYR TYR A . n 
A 1 145 ARG 145 137 145 ARG ARG A . n 
A 1 146 ASN 146 138 146 ASN ASN A . n 
A 1 147 PRO 147 139 147 PRO PRO A . n 
A 1 148 TYR 148 140 148 TYR TYR A . n 
A 1 149 THR 149 141 149 THR THR A . n 
A 1 150 HIS 150 142 150 HIS HIS A . n 
A 1 151 HIS 151 143 151 HIS HIS A . n 
A 1 152 PRO 152 144 152 PRO PRO A . n 
A 1 153 CYS 153 145 153 CYS CYS A . n 
A 1 154 VAL 154 146 154 VAL VAL A . n 
A 1 155 ARG 155 147 155 ARG ARG A . n 
A 1 156 GLN 156 148 156 GLN GLN A . n 
A 1 157 THR 157 149 157 THR THR A . n 
A 1 158 VAL 158 150 158 VAL VAL A . n 
A 1 159 GLU 159 151 159 GLU GLU A . n 
A 1 160 SER 160 152 160 SER SER A . n 
A 1 161 THR 161 153 161 THR THR A . n 
A 1 162 ALA 162 154 162 ALA ALA A . n 
A 1 163 ASN 163 155 163 ASN ASN A . n 
A 1 164 THR 164 156 164 THR THR A . n 
A 1 165 ASN 165 157 165 ASN ASN A . n 
A 1 166 VAL 166 158 166 VAL VAL A . n 
A 1 167 VAL 167 159 167 VAL VAL A . n 
A 1 168 MET 168 160 168 MET MET A . n 
A 1 169 HIS 169 161 169 HIS HIS A . n 
A 1 170 ALA 170 162 170 ALA ALA A . n 
A 1 171 GLY 171 163 171 GLY GLY A . n 
A 1 172 ARG 172 164 172 ARG ARG A . n 
A 1 173 PHE 173 165 173 PHE PHE A . n 
A 1 174 LEU 174 166 174 LEU LEU A . n 
A 1 175 ALA 175 167 175 ALA ALA A . n 
A 1 176 MET 176 168 176 MET MET A . n 
A 1 177 LYS 177 169 177 LYS LYS A . n 
A 1 178 GLU 178 170 178 GLU GLU A . n 
A 1 179 ASN 179 171 179 ASN ASN A . n 
A 1 180 GLY 180 172 180 GLY GLY A . n 
A 1 181 ASN 181 173 181 ASN ASN A . n 
A 1 182 ALA 182 174 182 ALA ALA A . n 
A 1 183 TYR 183 175 183 TYR TYR A . n 
A 1 184 GLU 184 176 184 GLU GLU A . n 
A 1 185 MET 185 177 185 MET MET A . n 
A 1 186 ASP 186 178 186 ASP ASP A . n 
A 1 187 PRO 187 179 187 PRO PRO A . n 
A 1 188 HIS 188 180 188 HIS HIS A . n 
A 1 189 THR 189 181 189 THR THR A . n 
A 1 190 LEU 190 182 190 LEU LEU A . n 
A 1 191 LYS 191 183 191 LYS LYS A . n 
A 1 192 THR 192 184 192 THR THR A . n 
A 1 193 LEU 193 185 193 LEU LEU A . n 
A 1 194 GLY 194 186 194 GLY GLY A . n 
A 1 195 TYR 195 187 195 TYR TYR A . n 
A 1 196 ASN 196 188 196 ASN ASN A . n 
A 1 197 PRO 197 189 197 PRO PRO A . n 
A 1 198 PHE 198 190 198 PHE PHE A . n 
A 1 199 ASN 199 191 199 ASN ASN A . n 
A 1 200 LEU 200 192 200 LEU LEU A . n 
A 1 201 PRO 201 193 201 PRO PRO A . n 
A 1 202 SER 202 194 202 SER SER A . n 
A 1 203 LYS 203 195 203 LYS LYS A . n 
A 1 204 THR 204 196 204 THR THR A . n 
A 1 205 MET 205 197 205 MET MET A . n 
A 1 206 THR 206 198 206 THR THR A . n 
A 1 207 ALA 207 199 207 ALA ALA A . n 
A 1 208 HIS 208 200 208 HIS HIS A . n 
A 1 209 PRO 209 201 209 PRO PRO A . n 
A 1 210 LYS 210 202 210 LYS LYS A . n 
A 1 211 GLN 211 203 211 GLN GLN A . n 
A 1 212 CYS 212 204 212 CYS CYS A . n 
A 1 213 SER 213 205 213 SER SER A . n 
A 1 214 VAL 214 206 214 VAL VAL A . n 
A 1 215 THR 215 207 215 THR THR A . n 
A 1 216 GLY 216 208 216 GLY GLY A . n 
A 1 217 ASN 217 209 217 ASN ASN A . n 
A 1 218 LEU 218 210 218 LEU LEU A . n 
A 1 219 VAL 219 211 219 VAL VAL A . n 
A 1 220 GLY 220 212 220 GLY GLY A . n 
A 1 221 PHE 221 213 221 PHE PHE A . n 
A 1 222 GLY 222 214 222 GLY GLY A . n 
A 1 223 TYR 223 215 223 TYR TYR A . n 
A 1 224 GLU 224 216 224 GLU GLU A . n 
A 1 225 ALA 225 217 225 ALA ALA A . n 
A 1 226 LYS 226 218 226 LYS LYS A . n 
A 1 227 GLY 227 219 227 GLY GLY A . n 
A 1 228 LEU 228 220 228 LEU LEU A . n 
A 1 229 ALA 229 221 229 ALA ALA A . n 
A 1 230 THR 230 222 230 THR THR A . n 
A 1 231 LYS 231 223 231 LYS LYS A . n 
A 1 232 ASP 232 224 232 ASP ASP A . n 
A 1 233 VAL 233 225 233 VAL VAL A . n 
A 1 234 TYR 234 226 234 TYR TYR A . n 
A 1 235 TYR 235 227 235 TYR TYR A . n 
A 1 236 PHE 236 228 236 PHE PHE A . n 
A 1 237 GLU 237 229 237 GLU GLU A . n 
A 1 238 VAL 238 230 238 VAL VAL A . n 
A 1 239 ASP 239 231 239 ASP ASP A . n 
A 1 240 PRO 240 232 240 PRO PRO A . n 
A 1 241 SER 241 233 241 SER SER A . n 
A 1 242 GLY 242 234 242 GLY GLY A . n 
A 1 243 LYS 243 235 243 LYS LYS A . n 
A 1 244 VAL 244 236 244 VAL VAL A . n 
A 1 245 VAL 245 237 245 VAL VAL A . n 
A 1 246 ARG 246 238 246 ARG ARG A . n 
A 1 247 ASP 247 239 247 ASP ASP A . n 
A 1 248 LEU 248 240 248 LEU LEU A . n 
A 1 249 TRP 249 241 249 TRP TRP A . n 
A 1 250 LEU 250 242 250 LEU LEU A . n 
A 1 251 GLU 251 243 251 GLU GLU A . n 
A 1 252 ALA 252 244 252 ALA ALA A . n 
A 1 253 PRO 253 245 253 PRO PRO A . n 
A 1 254 TRP 254 246 254 TRP TRP A . n 
A 1 255 CYS 255 247 255 CYS CYS A . n 
A 1 256 ALA 256 248 256 ALA ALA A . n 
A 1 257 PHE 257 249 257 PHE PHE A . n 
A 1 258 ILE 258 250 258 ILE ILE A . n 
A 1 259 HIS 259 251 259 HIS HIS A . n 
A 1 260 ASP 260 252 260 ASP ASP A . n 
A 1 261 CYS 261 253 261 CYS CYS A . n 
A 1 262 ALA 262 254 262 ALA ALA A . n 
A 1 263 LEU 263 255 263 LEU LEU A . n 
A 1 264 THR 264 256 264 THR THR A . n 
A 1 265 PRO 265 257 265 PRO PRO A . n 
A 1 266 ASN 266 258 266 ASN ASN A . n 
A 1 267 TYR 267 259 267 TYR TYR A . n 
A 1 268 LEU 268 260 268 LEU LEU A . n 
A 1 269 VAL 269 261 269 VAL VAL A . n 
A 1 270 LEU 270 262 270 LEU LEU A . n 
A 1 271 MET 271 263 271 MET MET A . n 
A 1 272 LEU 272 264 272 LEU LEU A . n 
A 1 273 TRP 273 265 273 TRP TRP A . n 
A 1 274 PRO 274 266 274 PRO PRO A . n 
A 1 275 PHE 275 267 275 PHE PHE A . n 
A 1 276 GLU 276 268 276 GLU GLU A . n 
A 1 277 ALA 277 269 277 ALA ALA A . n 
A 1 278 ASN 278 270 278 ASN ASN A . n 
A 1 279 LEU 279 271 279 LEU LEU A . n 
A 1 280 GLU 280 272 280 GLU GLU A . n 
A 1 281 ARG 281 273 281 ARG ARG A . n 
A 1 282 MET 282 274 282 MET MET A . n 
A 1 283 LYS 283 275 283 LYS LYS A . n 
A 1 284 ALA 284 276 284 ALA ALA A . n 
A 1 285 GLY 285 277 285 GLY GLY A . n 
A 1 286 GLY 286 278 286 GLY GLY A . n 
A 1 287 HIS 287 279 287 HIS HIS A . n 
A 1 288 HIS 288 280 288 HIS HIS A . n 
A 1 289 TRP 289 281 289 TRP TRP A . n 
A 1 290 ALA 290 282 290 ALA ALA A . n 
A 1 291 TYR 291 283 291 TYR TYR A . n 
A 1 292 ASP 292 284 292 ASP ASP A . n 
A 1 293 TYR 293 285 293 TYR TYR A . n 
A 1 294 THR 294 286 294 THR THR A . n 
A 1 295 LYS 295 287 295 LYS LYS A . n 
A 1 296 PRO 296 288 296 PRO PRO A . n 
A 1 297 ILE 297 289 297 ILE ILE A . n 
A 1 298 THR 298 290 298 THR THR A . n 
A 1 299 TRP 299 291 299 TRP TRP A . n 
A 1 300 ILE 300 292 300 ILE ILE A . n 
A 1 301 THR 301 293 301 THR THR A . n 
A 1 302 ILE 302 294 302 ILE ILE A . n 
A 1 303 PRO 303 295 303 PRO PRO A . n 
A 1 304 ARG 304 296 304 ARG ARG A . n 
A 1 305 GLY 305 297 305 GLY GLY A . n 
A 1 306 ALA 306 298 306 ALA ALA A . n 
A 1 307 LYS 307 299 307 LYS LYS A . n 
A 1 308 SER 308 300 308 SER SER A . n 
A 1 309 LYS 309 301 309 LYS LYS A . n 
A 1 310 ASP 310 302 310 ASP ASP A . n 
A 1 311 GLU 311 303 311 GLU GLU A . n 
A 1 312 VAL 312 304 312 VAL VAL A . n 
A 1 313 LYS 313 305 313 LYS LYS A . n 
A 1 314 TYR 314 306 314 TYR TYR A . n 
A 1 315 TRP 315 307 315 TRP TRP A . n 
A 1 316 HIS 316 308 316 HIS HIS A . n 
A 1 317 TRP 317 309 317 TRP TRP A . n 
A 1 318 LYS 318 310 318 LYS LYS A . n 
A 1 319 ASN 319 311 319 ASN ASN A . n 
A 1 320 GLY 320 312 320 GLY GLY A . n 
A 1 321 MET 321 313 321 MET MET A . n 
A 1 322 PRO 322 314 322 PRO PRO A . n 
A 1 323 ILE 323 315 323 ILE ILE A . n 
A 1 324 HIS 324 316 324 HIS HIS A . n 
A 1 325 THR 325 317 325 THR THR A . n 
A 1 326 ALA 326 318 326 ALA ALA A . n 
A 1 327 SER 327 319 327 SER SER A . n 
A 1 328 GLY 328 320 328 GLY GLY A . n 
A 1 329 PHE 329 321 329 PHE PHE A . n 
A 1 330 GLU 330 322 330 GLU GLU A . n 
A 1 331 ASP 331 323 331 ASP ASP A . n 
A 1 332 GLU 332 324 332 GLU GLU A . n 
A 1 333 GLN 333 325 333 GLN GLN A . n 
A 1 334 GLY 334 326 334 GLY GLY A . n 
A 1 335 ARG 335 327 335 ARG ARG A . n 
A 1 336 ILE 336 328 336 ILE ILE A . n 
A 1 337 ILE 337 329 337 ILE ILE A . n 
A 1 338 ILE 338 330 338 ILE ILE A . n 
A 1 339 ASP 339 331 339 ASP ASP A . n 
A 1 340 SER 340 332 340 SER SER A . n 
A 1 341 SER 341 333 341 SER SER A . n 
A 1 342 LEU 342 334 342 LEU LEU A . n 
A 1 343 VAL 343 335 343 VAL VAL A . n 
A 1 344 HIS 344 336 344 HIS HIS A . n 
A 1 345 GLY 345 337 345 GLY GLY A . n 
A 1 346 ASN 346 338 346 ASN ASN A . n 
A 1 347 ALA 347 339 347 ALA ALA A . n 
A 1 348 PHE 348 340 348 PHE PHE A . n 
A 1 349 PRO 349 341 349 PRO PRO A . n 
A 1 350 PHE 350 342 350 PHE PHE A . n 
A 1 351 PHE 351 343 351 PHE PHE A . n 
A 1 352 PRO 352 344 352 PRO PRO A . n 
A 1 353 PRO 353 345 353 PRO PRO A . n 
A 1 354 ASP 354 346 354 ASP ASP A . n 
A 1 355 SER 355 347 355 SER SER A . n 
A 1 356 ASP 356 348 356 ASP ASP A . n 
A 1 357 GLU 357 349 357 GLU GLU A . n 
A 1 358 GLN 358 350 358 GLN GLN A . n 
A 1 359 LYS 359 351 359 LYS LYS A . n 
A 1 360 LYS 360 352 360 LYS LYS A . n 
A 1 361 LYS 361 353 361 LYS LYS A . n 
A 1 362 GLN 362 354 362 GLN GLN A . n 
A 1 363 GLU 363 355 363 GLU GLU A . n 
A 1 364 ALA 364 356 364 ALA ALA A . n 
A 1 365 ASP 365 357 365 ASP ASP A . n 
A 1 366 GLY 366 358 366 GLY GLY A . n 
A 1 367 THR 367 359 367 THR THR A . n 
A 1 368 PRO 368 360 368 PRO PRO A . n 
A 1 369 LYS 369 361 369 LYS LYS A . n 
A 1 370 ALA 370 362 370 ALA ALA A . n 
A 1 371 GLN 371 363 371 GLN GLN A . n 
A 1 372 PHE 372 364 372 PHE PHE A . n 
A 1 373 VAL 373 365 373 VAL VAL A . n 
A 1 374 ARG 374 366 374 ARG ARG A . n 
A 1 375 TRP 375 367 375 TRP TRP A . n 
A 1 376 THR 376 368 376 THR THR A . n 
A 1 377 ILE 377 369 377 ILE ILE A . n 
A 1 378 ASP 378 370 378 ASP ASP A . n 
A 1 379 PRO 379 371 379 PRO PRO A . n 
A 1 380 ARG 380 372 380 ARG ARG A . n 
A 1 381 LYS 381 373 381 LYS LYS A . n 
A 1 382 ASP 382 374 382 ASP ASP A . n 
A 1 383 ASN 383 375 383 ASN ASN A . n 
A 1 384 ASN 384 376 384 ASN ASN A . n 
A 1 385 GLU 385 377 385 GLU GLU A . n 
A 1 386 GLN 386 378 386 GLN GLN A . n 
A 1 387 LEU 387 379 387 LEU LEU A . n 
A 1 388 PRO 388 380 388 PRO PRO A . n 
A 1 389 ASP 389 381 389 ASP ASP A . n 
A 1 390 PRO 390 382 390 PRO PRO A . n 
A 1 391 GLU 391 383 391 GLU GLU A . n 
A 1 392 VAL 392 384 392 VAL VAL A . n 
A 1 393 ILE 393 385 393 ILE ILE A . n 
A 1 394 LEU 394 386 394 LEU LEU A . n 
A 1 395 ASP 395 387 395 ASP ASP A . n 
A 1 396 THR 396 388 396 THR THR A . n 
A 1 397 PRO 397 389 397 PRO PRO A . n 
A 1 398 SER 398 390 398 SER SER A . n 
A 1 399 GLU 399 391 399 GLU GLU A . n 
A 1 400 PHE 400 392 400 PHE PHE A . n 
A 1 401 PRO 401 393 401 PRO PRO A . n 
A 1 402 GLN 402 394 402 GLN GLN A . n 
A 1 403 ILE 403 395 403 ILE ILE A . n 
A 1 404 ASP 404 396 404 ASP ASP A . n 
A 1 405 ASN 405 397 405 ASN ASN A . n 
A 1 406 ARG 406 398 406 ARG ARG A . n 
A 1 407 PHE 407 399 407 PHE PHE A . n 
A 1 408 MET 408 400 408 MET MET A . n 
A 1 409 GLY 409 401 409 GLY GLY A . n 
A 1 410 VAL 410 402 410 VAL VAL A . n 
A 1 411 GLU 411 403 411 GLU GLU A . n 
A 1 412 TYR 412 404 412 TYR TYR A . n 
A 1 413 SER 413 405 413 SER SER A . n 
A 1 414 SER 414 406 414 SER SER A . n 
A 1 415 ALA 415 407 415 ALA ALA A . n 
A 1 416 PHE 416 408 416 PHE PHE A . n 
A 1 417 ILE 417 409 417 ILE ILE A . n 
A 1 418 ASN 418 410 418 ASN ASN A . n 
A 1 419 VAL 419 411 419 VAL VAL A . n 
A 1 420 PHE 420 412 420 PHE PHE A . n 
A 1 421 VAL 421 413 421 VAL VAL A . n 
A 1 422 PRO 422 414 422 PRO PRO A . n 
A 1 423 ASP 423 415 423 ASP ASP A . n 
A 1 424 ARG 424 416 424 ARG ARG A . n 
A 1 425 SER 425 417 425 SER SER A . n 
A 1 426 ASP 426 418 426 ASP ASP A . n 
A 1 427 GLY 427 419 427 GLY GLY A . n 
A 1 428 ASN 428 420 428 ASN ASN A . n 
A 1 429 LYS 429 421 429 LYS LYS A . n 
A 1 430 ASN 430 422 430 ASN ASN A . n 
A 1 431 VAL 431 423 431 VAL VAL A . n 
A 1 432 PHE 432 424 432 PHE PHE A . n 
A 1 433 GLN 433 425 433 GLN GLN A . n 
A 1 434 GLY 434 426 434 GLY GLY A . n 
A 1 435 LEU 435 427 435 LEU LEU A . n 
A 1 436 ASN 436 428 436 ASN ASN A . n 
A 1 437 GLY 437 429 437 GLY GLY A . n 
A 1 438 LEU 438 430 438 LEU LEU A . n 
A 1 439 ALA 439 431 439 ALA ALA A . n 
A 1 440 HIS 440 432 440 HIS HIS A . n 
A 1 441 TYR 441 433 441 TYR TYR A . n 
A 1 442 LYS 442 434 442 LYS LYS A . n 
A 1 443 ARG 443 435 443 ARG ARG A . n 
A 1 444 LYS 444 436 444 LYS LYS A . n 
A 1 445 GLU 445 437 445 GLU GLU A . n 
A 1 446 GLY 446 438 446 GLY GLY A . n 
A 1 447 THR 447 439 447 THR THR A . n 
A 1 448 THR 448 440 448 THR THR A . n 
A 1 449 GLU 449 441 449 GLU GLU A . n 
A 1 450 TRP 450 442 450 TRP TRP A . n 
A 1 451 TYR 451 443 451 TYR TYR A . n 
A 1 452 TYR 452 444 452 TYR TYR A . n 
A 1 453 ALA 453 445 453 ALA ALA A . n 
A 1 454 GLY 454 446 454 GLY GLY A . n 
A 1 455 ASP 455 447 455 ASP ASP A . n 
A 1 456 ASN 456 448 456 ASN ASN A . n 
A 1 457 CYS 457 449 457 CYS CYS A . n 
A 1 458 LEU 458 450 458 LEU LEU A . n 
A 1 459 ILE 459 451 459 ILE ILE A . n 
A 1 460 GLN 460 452 460 GLN GLN A . n 
A 1 461 GLU 461 453 461 GLU GLU A . n 
A 1 462 PRO 462 454 462 PRO PRO A . n 
A 1 463 VAL 463 455 463 VAL VAL A . n 
A 1 464 PHE 464 456 464 PHE PHE A . n 
A 1 465 SER 465 457 465 SER SER A . n 
A 1 466 PRO 466 458 466 PRO PRO A . n 
A 1 467 ARG 467 459 467 ARG ARG A . n 
A 1 468 SER 468 460 468 SER SER A . n 
A 1 469 LYS 469 461 469 LYS LYS A . n 
A 1 470 ASP 470 462 470 ASP ASP A . n 
A 1 471 ALA 471 463 471 ALA ALA A . n 
A 1 472 PRO 472 464 472 PRO PRO A . n 
A 1 473 GLU 473 465 473 GLU GLU A . n 
A 1 474 GLY 474 466 474 GLY GLY A . n 
A 1 475 ASP 475 467 475 ASP ASP A . n 
A 1 476 GLY 476 468 476 GLY GLY A . n 
A 1 477 PHE 477 469 477 PHE PHE A . n 
A 1 478 VAL 478 470 478 VAL VAL A . n 
A 1 479 LEU 479 471 479 LEU LEU A . n 
A 1 480 ALA 480 472 480 ALA ALA A . n 
A 1 481 ILE 481 473 481 ILE ILE A . n 
A 1 482 VAL 482 474 482 VAL VAL A . n 
A 1 483 ASP 483 475 483 ASP ASP A . n 
A 1 484 ARG 484 476 484 ARG ARG A . n 
A 1 485 LEU 485 477 485 LEU LEU A . n 
A 1 486 ASP 486 478 486 ASP ASP A . n 
A 1 487 LEU 487 479 487 LEU LEU A . n 
A 1 488 ASN 488 480 488 ASN ASN A . n 
A 1 489 ARG 489 481 489 ARG ARG A . n 
A 1 490 SER 490 482 490 SER SER A . n 
A 1 491 GLU 491 483 491 GLU GLU A . n 
A 1 492 VAL 492 484 492 VAL VAL A . n 
A 1 493 VAL 493 485 493 VAL VAL A . n 
A 1 494 VAL 494 486 494 VAL VAL A . n 
A 1 495 ILE 495 487 495 ILE ILE A . n 
A 1 496 ASP 496 488 496 ASP ASP A . n 
A 1 497 THR 497 489 497 THR THR A . n 
A 1 498 ARG 498 490 498 ARG ARG A . n 
A 1 499 ASP 499 491 499 ASP ASP A . n 
A 1 500 PHE 500 492 500 PHE PHE A . n 
A 1 501 THR 501 493 501 THR THR A . n 
A 1 502 LYS 502 494 502 LYS LYS A . n 
A 1 503 ALA 503 495 503 ALA ALA A . n 
A 1 504 VAL 504 496 504 VAL VAL A . n 
A 1 505 ALA 505 497 505 ALA ALA A . n 
A 1 506 ALA 506 498 506 ALA ALA A . n 
A 1 507 VAL 507 499 507 VAL VAL A . n 
A 1 508 GLN 508 500 508 GLN GLN A . n 
A 1 509 LEU 509 501 509 LEU LEU A . n 
A 1 510 PRO 510 502 510 PRO PRO A . n 
A 1 511 PHE 511 503 511 PHE PHE A . n 
A 1 512 ALA 512 504 512 ALA ALA A . n 
A 1 513 ILE 513 505 513 ILE ILE A . n 
A 1 514 ARG 514 506 514 ARG ARG A . n 
A 1 515 SER 515 507 515 SER SER A . n 
A 1 516 GLY 516 508 516 GLY GLY A . n 
A 1 517 ILE 517 509 517 ILE ILE A . n 
A 1 518 HIS 518 510 518 HIS HIS A . n 
A 1 519 GLY 519 511 519 GLY GLY A . n 
A 1 520 GLN 520 512 520 GLN GLN A . n 
A 1 521 TRP 521 513 521 TRP TRP A . n 
A 1 522 ILE 522 514 522 ILE ILE A . n 
A 1 523 PRO 523 515 523 PRO PRO A . n 
A 1 524 GLY 524 516 524 GLY GLY A . n 
A 1 525 GLU 525 517 525 GLU GLU A . n 
A 1 526 VAL 526 518 526 VAL VAL A . n 
A 1 527 THR 527 519 527 THR THR A . n 
A 1 528 PRO 528 520 528 PRO PRO A . n 
A 1 529 ASP 529 521 529 ASP ASP A . n 
A 1 530 PHE 530 522 530 PHE PHE A . n 
A 1 531 GLU 531 523 531 GLU GLU A . n 
A 1 532 THR 532 524 532 THR THR A . n 
A 1 533 LYS 533 525 533 LYS LYS A . n 
A 1 534 GLY 534 526 534 GLY GLY A . n 
A 1 535 LEU 535 527 535 LEU LEU A . n 
A 1 536 VAL 536 528 536 VAL VAL A . n 
A 1 537 ASP 537 529 537 ASP ASP A . n 
A 1 538 LEU 538 530 538 LEU LEU A . n 
A 1 539 PRO 539 531 539 PRO PRO A . n 
A 1 540 LYS 540 532 540 LYS LYS A . n 
A 1 541 GLU 541 533 541 GLU GLU A . n 
A 1 542 GLU 542 534 542 GLU GLU A . n 
A 1 543 HIS 543 535 543 HIS HIS A . n 
A 1 544 TRP 544 536 544 TRP TRP A . n 
A 1 545 ALA 545 537 545 ALA ALA A . n 
A 1 546 PRO 546 538 546 PRO PRO A . n 
A 1 547 LEU 547 539 547 LEU LEU A . n 
A 1 548 SER 548 540 548 SER SER A . n 
A 1 549 GLN 549 541 549 GLN GLN A . n 
A 1 550 SER 550 542 550 SER SER A . n 
A 1 551 PRO 551 543 551 PRO PRO A . n 
A 1 552 TYR 552 544 552 TYR TYR A . n 
A 1 553 ASP 553 545 553 ASP ASP A . n 
A 1 554 PRO 554 546 554 PRO PRO A . n 
A 1 555 ASP 555 547 555 ASP ASP A . n 
A 1 556 ALA 556 548 556 ALA ALA A . n 
B 1 1   MET 1   -7  ?   ?   ?   B . n 
B 1 2   TRP 2   -6  ?   ?   ?   B . n 
B 1 3   SER 3   -5  ?   ?   ?   B . n 
B 1 4   HIS 4   -4  ?   ?   ?   B . n 
B 1 5   PRO 5   -3  ?   ?   ?   B . n 
B 1 6   GLN 6   -2  ?   ?   ?   B . n 
B 1 7   PHE 7   -1  ?   ?   ?   B . n 
B 1 8   GLU 8   0   ?   ?   ?   B . n 
B 1 9   LYS 9   1   ?   ?   ?   B . n 
B 1 10  ALA 10  2   ?   ?   ?   B . n 
B 1 11  PRO 11  3   ?   ?   ?   B . n 
B 1 12  THR 12  4   ?   ?   ?   B . n 
B 1 13  ALA 13  5   ?   ?   ?   B . n 
B 1 14  THR 14  6   ?   ?   ?   B . n 
B 1 15  GLN 15  7   ?   ?   ?   B . n 
B 1 16  GLU 16  8   ?   ?   ?   B . n 
B 1 17  PRO 17  9   ?   ?   ?   B . n 
B 1 18  VAL 18  10  ?   ?   ?   B . n 
B 1 19  PRO 19  11  ?   ?   ?   B . n 
B 1 20  VAL 20  12  ?   ?   ?   B . n 
B 1 21  PRO 21  13  ?   ?   ?   B . n 
B 1 22  VAL 22  14  ?   ?   ?   B . n 
B 1 23  THR 23  15  ?   ?   ?   B . n 
B 1 24  SER 24  16  ?   ?   ?   B . n 
B 1 25  LYS 25  17  ?   ?   ?   B . n 
B 1 26  ALA 26  18  ?   ?   ?   B . n 
B 1 27  ALA 27  19  ?   ?   ?   B . n 
B 1 28  PRO 28  20  ?   ?   ?   B . n 
B 1 29  SER 29  21  ?   ?   ?   B . n 
B 1 30  HIS 30  22  ?   ?   ?   B . n 
B 1 31  GLY 31  23  ?   ?   ?   B . n 
B 1 32  TYR 32  24  32  TYR TYR B . n 
B 1 33  VAL 33  25  33  VAL VAL B . n 
B 1 34  HIS 34  26  34  HIS HIS B . n 
B 1 35  PRO 35  27  35  PRO PRO B . n 
B 1 36  THR 36  28  36  THR THR B . n 
B 1 37  ASP 37  29  37  ASP ASP B . n 
B 1 38  ILE 38  30  38  ILE ILE B . n 
B 1 39  LEU 39  31  39  LEU LEU B . n 
B 1 40  PRO 40  32  40  PRO PRO B . n 
B 1 41  SER 41  33  41  SER SER B . n 
B 1 42  GLY 42  34  42  GLY GLY B . n 
B 1 43  TRP 43  35  43  TRP TRP B . n 
B 1 44  PRO 44  36  44  PRO PRO B . n 
B 1 45  THR 45  37  45  THR THR B . n 
B 1 46  ALA 46  38  46  ALA ALA B . n 
B 1 47  THR 47  39  47  THR THR B . n 
B 1 48  ASP 48  40  48  ASP ASP B . n 
B 1 49  LEU 49  41  49  LEU LEU B . n 
B 1 50  SER 50  42  50  SER SER B . n 
B 1 51  GLY 51  43  51  GLY GLY B . n 
B 1 52  GLY 52  44  52  GLY GLY B . n 
B 1 53  ALA 53  45  53  ALA ALA B . n 
B 1 54  GLN 54  46  54  GLN GLN B . n 
B 1 55  PRO 55  47  55  PRO PRO B . n 
B 1 56  ARG 56  48  56  ARG ARG B . n 
B 1 57  ARG 57  49  57  ARG ARG B . n 
B 1 58  PHE 58  50  58  PHE PHE B . n 
B 1 59  GLU 59  51  59  GLU GLU B . n 
B 1 60  GLY 60  52  60  GLY GLY B . n 
B 1 61  THR 61  53  61  THR THR B . n 
B 1 62  ILE 62  54  62  ILE ILE B . n 
B 1 63  PHE 63  55  63  PHE PHE B . n 
B 1 64  ASP 64  56  64  ASP ASP B . n 
B 1 65  VAL 65  57  65  VAL VAL B . n 
B 1 66  MET 66  58  66  MET MET B . n 
B 1 67  THR 67  59  67  THR THR B . n 
B 1 68  ARG 68  60  68  ARG ARG B . n 
B 1 69  GLY 69  61  69  GLY GLY B . n 
B 1 70  THR 70  62  70  THR THR B . n 
B 1 71  ILE 71  63  71  ILE ILE B . n 
B 1 72  PRO 72  64  72  PRO PRO B . n 
B 1 73  LYS 73  65  73  LYS LYS B . n 
B 1 74  GLU 74  66  74  GLU GLU B . n 
B 1 75  LEU 75  67  75  LEU LEU B . n 
B 1 76  HIS 76  68  76  HIS HIS B . n 
B 1 77  GLY 77  69  77  GLY GLY B . n 
B 1 78  THR 78  70  78  THR THR B . n 
B 1 79  PHE 79  71  79  PHE PHE B . n 
B 1 80  TYR 80  72  80  TYR TYR B . n 
B 1 81  ARG 81  73  81  ARG ARG B . n 
B 1 82  ILE 82  74  82  ILE ILE B . n 
B 1 83  MET 83  75  83  MET MET B . n 
B 1 84  PRO 84  76  84  PRO PRO B . n 
B 1 85  ASP 85  77  85  ASP ASP B . n 
B 1 86  TYR 86  78  86  TYR TYR B . n 
B 1 87  ALA 87  79  87  ALA ALA B . n 
B 1 88  GLN 88  80  88  GLN GLN B . n 
B 1 89  PRO 89  81  89  PRO PRO B . n 
B 1 90  PRO 90  82  90  PRO PRO B . n 
B 1 91  THR 91  83  91  THR THR B . n 
B 1 92  TYR 92  84  92  TYR TYR B . n 
B 1 93  TYR 93  85  93  TYR TYR B . n 
B 1 94  LYS 94  86  94  LYS LYS B . n 
B 1 95  GLY 95  87  95  GLY GLY B . n 
B 1 96  GLY 96  88  96  GLY GLY B . n 
B 1 97  GLU 97  89  97  GLU GLU B . n 
B 1 98  LEU 98  90  98  LEU LEU B . n 
B 1 99  ASN 99  91  99  ASN ASN B . n 
B 1 100 ALA 100 92  100 ALA ALA B . n 
B 1 101 PRO 101 93  101 PRO PRO B . n 
B 1 102 ILE 102 94  102 ILE ILE B . n 
B 1 103 ASP 103 95  103 ASP ASP B . n 
B 1 104 GLY 104 96  104 GLY GLY B . n 
B 1 105 ASP 105 97  105 ASP ASP B . n 
B 1 106 GLY 106 98  106 GLY GLY B . n 
B 1 107 THR 107 99  107 THR THR B . n 
B 1 108 VAL 108 100 108 VAL VAL B . n 
B 1 109 ALA 109 101 109 ALA ALA B . n 
B 1 110 ALA 110 102 110 ALA ALA B . n 
B 1 111 PHE 111 103 111 PHE PHE B . n 
B 1 112 ARG 112 104 112 ARG ARG B . n 
B 1 113 PHE 113 105 113 PHE PHE B . n 
B 1 114 LYS 114 106 114 LYS LYS B . n 
B 1 115 ASP 115 107 115 ASP ASP B . n 
B 1 116 GLY 116 108 116 GLY GLY B . n 
B 1 117 LYS 117 109 117 LYS LYS B . n 
B 1 118 VAL 118 110 118 VAL VAL B . n 
B 1 119 ASP 119 111 119 ASP ASP B . n 
B 1 120 TYR 120 112 120 TYR TYR B . n 
B 1 121 ARG 121 113 121 ARG ARG B . n 
B 1 122 GLN 122 114 122 GLN GLN B . n 
B 1 123 ARG 123 115 123 ARG ARG B . n 
B 1 124 PHE 124 116 124 PHE PHE B . n 
B 1 125 VAL 125 117 125 VAL VAL B . n 
B 1 126 GLU 126 118 126 GLU GLU B . n 
B 1 127 THR 127 119 127 THR THR B . n 
B 1 128 ASP 128 120 128 ASP ASP B . n 
B 1 129 ARG 129 121 129 ARG ARG B . n 
B 1 130 PHE 130 122 130 PHE PHE B . n 
B 1 131 LYS 131 123 131 LYS LYS B . n 
B 1 132 VAL 132 124 132 VAL VAL B . n 
B 1 133 GLU 133 125 133 GLU GLU B . n 
B 1 134 ARG 134 126 134 ARG ARG B . n 
B 1 135 ARG 135 127 135 ARG ARG B . n 
B 1 136 ALA 136 128 136 ALA ALA B . n 
B 1 137 ARG 137 129 137 ARG ARG B . n 
B 1 138 LYS 138 130 138 LYS LYS B . n 
B 1 139 SER 139 131 139 SER SER B . n 
B 1 140 MET 140 132 140 MET MET B . n 
B 1 141 TYR 141 133 141 TYR TYR B . n 
B 1 142 GLY 142 134 142 GLY GLY B . n 
B 1 143 LEU 143 135 143 LEU LEU B . n 
B 1 144 TYR 144 136 144 TYR TYR B . n 
B 1 145 ARG 145 137 145 ARG ARG B . n 
B 1 146 ASN 146 138 146 ASN ASN B . n 
B 1 147 PRO 147 139 147 PRO PRO B . n 
B 1 148 TYR 148 140 148 TYR TYR B . n 
B 1 149 THR 149 141 149 THR THR B . n 
B 1 150 HIS 150 142 150 HIS HIS B . n 
B 1 151 HIS 151 143 151 HIS HIS B . n 
B 1 152 PRO 152 144 152 PRO PRO B . n 
B 1 153 CYS 153 145 153 CYS CYS B . n 
B 1 154 VAL 154 146 154 VAL VAL B . n 
B 1 155 ARG 155 147 155 ARG ARG B . n 
B 1 156 GLN 156 148 156 GLN GLN B . n 
B 1 157 THR 157 149 157 THR THR B . n 
B 1 158 VAL 158 150 158 VAL VAL B . n 
B 1 159 GLU 159 151 159 GLU GLU B . n 
B 1 160 SER 160 152 160 SER SER B . n 
B 1 161 THR 161 153 161 THR THR B . n 
B 1 162 ALA 162 154 162 ALA ALA B . n 
B 1 163 ASN 163 155 163 ASN ASN B . n 
B 1 164 THR 164 156 164 THR THR B . n 
B 1 165 ASN 165 157 165 ASN ASN B . n 
B 1 166 VAL 166 158 166 VAL VAL B . n 
B 1 167 VAL 167 159 167 VAL VAL B . n 
B 1 168 MET 168 160 168 MET MET B . n 
B 1 169 HIS 169 161 169 HIS HIS B . n 
B 1 170 ALA 170 162 170 ALA ALA B . n 
B 1 171 GLY 171 163 171 GLY GLY B . n 
B 1 172 ARG 172 164 172 ARG ARG B . n 
B 1 173 PHE 173 165 173 PHE PHE B . n 
B 1 174 LEU 174 166 174 LEU LEU B . n 
B 1 175 ALA 175 167 175 ALA ALA B . n 
B 1 176 MET 176 168 176 MET MET B . n 
B 1 177 LYS 177 169 177 LYS LYS B . n 
B 1 178 GLU 178 170 178 GLU GLU B . n 
B 1 179 ASN 179 171 179 ASN ASN B . n 
B 1 180 GLY 180 172 180 GLY GLY B . n 
B 1 181 ASN 181 173 181 ASN ASN B . n 
B 1 182 ALA 182 174 182 ALA ALA B . n 
B 1 183 TYR 183 175 183 TYR TYR B . n 
B 1 184 GLU 184 176 184 GLU GLU B . n 
B 1 185 MET 185 177 185 MET MET B . n 
B 1 186 ASP 186 178 186 ASP ASP B . n 
B 1 187 PRO 187 179 187 PRO PRO B . n 
B 1 188 HIS 188 180 188 HIS HIS B . n 
B 1 189 THR 189 181 189 THR THR B . n 
B 1 190 LEU 190 182 190 LEU LEU B . n 
B 1 191 LYS 191 183 191 LYS LYS B . n 
B 1 192 THR 192 184 192 THR THR B . n 
B 1 193 LEU 193 185 193 LEU LEU B . n 
B 1 194 GLY 194 186 194 GLY GLY B . n 
B 1 195 TYR 195 187 195 TYR TYR B . n 
B 1 196 ASN 196 188 196 ASN ASN B . n 
B 1 197 PRO 197 189 197 PRO PRO B . n 
B 1 198 PHE 198 190 198 PHE PHE B . n 
B 1 199 ASN 199 191 199 ASN ASN B . n 
B 1 200 LEU 200 192 200 LEU LEU B . n 
B 1 201 PRO 201 193 201 PRO PRO B . n 
B 1 202 SER 202 194 202 SER SER B . n 
B 1 203 LYS 203 195 203 LYS LYS B . n 
B 1 204 THR 204 196 204 THR THR B . n 
B 1 205 MET 205 197 205 MET MET B . n 
B 1 206 THR 206 198 206 THR THR B . n 
B 1 207 ALA 207 199 207 ALA ALA B . n 
B 1 208 HIS 208 200 208 HIS HIS B . n 
B 1 209 PRO 209 201 209 PRO PRO B . n 
B 1 210 LYS 210 202 210 LYS LYS B . n 
B 1 211 GLN 211 203 211 GLN GLN B . n 
B 1 212 CYS 212 204 212 CYS CYS B . n 
B 1 213 SER 213 205 213 SER SER B . n 
B 1 214 VAL 214 206 214 VAL VAL B . n 
B 1 215 THR 215 207 215 THR THR B . n 
B 1 216 GLY 216 208 216 GLY GLY B . n 
B 1 217 ASN 217 209 217 ASN ASN B . n 
B 1 218 LEU 218 210 218 LEU LEU B . n 
B 1 219 VAL 219 211 219 VAL VAL B . n 
B 1 220 GLY 220 212 220 GLY GLY B . n 
B 1 221 PHE 221 213 221 PHE PHE B . n 
B 1 222 GLY 222 214 222 GLY GLY B . n 
B 1 223 TYR 223 215 223 TYR TYR B . n 
B 1 224 GLU 224 216 224 GLU GLU B . n 
B 1 225 ALA 225 217 225 ALA ALA B . n 
B 1 226 LYS 226 218 226 LYS LYS B . n 
B 1 227 GLY 227 219 227 GLY GLY B . n 
B 1 228 LEU 228 220 228 LEU LEU B . n 
B 1 229 ALA 229 221 229 ALA ALA B . n 
B 1 230 THR 230 222 230 THR THR B . n 
B 1 231 LYS 231 223 231 LYS LYS B . n 
B 1 232 ASP 232 224 232 ASP ASP B . n 
B 1 233 VAL 233 225 233 VAL VAL B . n 
B 1 234 TYR 234 226 234 TYR TYR B . n 
B 1 235 TYR 235 227 235 TYR TYR B . n 
B 1 236 PHE 236 228 236 PHE PHE B . n 
B 1 237 GLU 237 229 237 GLU GLU B . n 
B 1 238 VAL 238 230 238 VAL VAL B . n 
B 1 239 ASP 239 231 239 ASP ASP B . n 
B 1 240 PRO 240 232 240 PRO PRO B . n 
B 1 241 SER 241 233 241 SER SER B . n 
B 1 242 GLY 242 234 242 GLY GLY B . n 
B 1 243 LYS 243 235 243 LYS LYS B . n 
B 1 244 VAL 244 236 244 VAL VAL B . n 
B 1 245 VAL 245 237 245 VAL VAL B . n 
B 1 246 ARG 246 238 246 ARG ARG B . n 
B 1 247 ASP 247 239 247 ASP ASP B . n 
B 1 248 LEU 248 240 248 LEU LEU B . n 
B 1 249 TRP 249 241 249 TRP TRP B . n 
B 1 250 LEU 250 242 250 LEU LEU B . n 
B 1 251 GLU 251 243 251 GLU GLU B . n 
B 1 252 ALA 252 244 252 ALA ALA B . n 
B 1 253 PRO 253 245 253 PRO PRO B . n 
B 1 254 TRP 254 246 254 TRP TRP B . n 
B 1 255 CYS 255 247 255 CYS CYS B . n 
B 1 256 ALA 256 248 256 ALA ALA B . n 
B 1 257 PHE 257 249 257 PHE PHE B . n 
B 1 258 ILE 258 250 258 ILE ILE B . n 
B 1 259 HIS 259 251 259 HIS HIS B . n 
B 1 260 ASP 260 252 260 ASP ASP B . n 
B 1 261 CYS 261 253 261 CYS CYS B . n 
B 1 262 ALA 262 254 262 ALA ALA B . n 
B 1 263 LEU 263 255 263 LEU LEU B . n 
B 1 264 THR 264 256 264 THR THR B . n 
B 1 265 PRO 265 257 265 PRO PRO B . n 
B 1 266 ASN 266 258 266 ASN ASN B . n 
B 1 267 TYR 267 259 267 TYR TYR B . n 
B 1 268 LEU 268 260 268 LEU LEU B . n 
B 1 269 VAL 269 261 269 VAL VAL B . n 
B 1 270 LEU 270 262 270 LEU LEU B . n 
B 1 271 MET 271 263 271 MET MET B . n 
B 1 272 LEU 272 264 272 LEU LEU B . n 
B 1 273 TRP 273 265 273 TRP TRP B . n 
B 1 274 PRO 274 266 274 PRO PRO B . n 
B 1 275 PHE 275 267 275 PHE PHE B . n 
B 1 276 GLU 276 268 276 GLU GLU B . n 
B 1 277 ALA 277 269 277 ALA ALA B . n 
B 1 278 ASN 278 270 278 ASN ASN B . n 
B 1 279 LEU 279 271 279 LEU LEU B . n 
B 1 280 GLU 280 272 280 GLU GLU B . n 
B 1 281 ARG 281 273 281 ARG ARG B . n 
B 1 282 MET 282 274 282 MET MET B . n 
B 1 283 LYS 283 275 283 LYS LYS B . n 
B 1 284 ALA 284 276 284 ALA ALA B . n 
B 1 285 GLY 285 277 285 GLY GLY B . n 
B 1 286 GLY 286 278 286 GLY GLY B . n 
B 1 287 HIS 287 279 287 HIS HIS B . n 
B 1 288 HIS 288 280 288 HIS HIS B . n 
B 1 289 TRP 289 281 289 TRP TRP B . n 
B 1 290 ALA 290 282 290 ALA ALA B . n 
B 1 291 TYR 291 283 291 TYR TYR B . n 
B 1 292 ASP 292 284 292 ASP ASP B . n 
B 1 293 TYR 293 285 293 TYR TYR B . n 
B 1 294 THR 294 286 294 THR THR B . n 
B 1 295 LYS 295 287 295 LYS LYS B . n 
B 1 296 PRO 296 288 296 PRO PRO B . n 
B 1 297 ILE 297 289 297 ILE ILE B . n 
B 1 298 THR 298 290 298 THR THR B . n 
B 1 299 TRP 299 291 299 TRP TRP B . n 
B 1 300 ILE 300 292 300 ILE ILE B . n 
B 1 301 THR 301 293 301 THR THR B . n 
B 1 302 ILE 302 294 302 ILE ILE B . n 
B 1 303 PRO 303 295 303 PRO PRO B . n 
B 1 304 ARG 304 296 304 ARG ARG B . n 
B 1 305 GLY 305 297 305 GLY GLY B . n 
B 1 306 ALA 306 298 306 ALA ALA B . n 
B 1 307 LYS 307 299 307 LYS LYS B . n 
B 1 308 SER 308 300 308 SER SER B . n 
B 1 309 LYS 309 301 309 LYS LYS B . n 
B 1 310 ASP 310 302 310 ASP ASP B . n 
B 1 311 GLU 311 303 311 GLU GLU B . n 
B 1 312 VAL 312 304 312 VAL VAL B . n 
B 1 313 LYS 313 305 313 LYS LYS B . n 
B 1 314 TYR 314 306 314 TYR TYR B . n 
B 1 315 TRP 315 307 315 TRP TRP B . n 
B 1 316 HIS 316 308 316 HIS HIS B . n 
B 1 317 TRP 317 309 317 TRP TRP B . n 
B 1 318 LYS 318 310 318 LYS LYS B . n 
B 1 319 ASN 319 311 319 ASN ASN B . n 
B 1 320 GLY 320 312 320 GLY GLY B . n 
B 1 321 MET 321 313 321 MET MET B . n 
B 1 322 PRO 322 314 322 PRO PRO B . n 
B 1 323 ILE 323 315 323 ILE ILE B . n 
B 1 324 HIS 324 316 324 HIS HIS B . n 
B 1 325 THR 325 317 325 THR THR B . n 
B 1 326 ALA 326 318 326 ALA ALA B . n 
B 1 327 SER 327 319 327 SER SER B . n 
B 1 328 GLY 328 320 328 GLY GLY B . n 
B 1 329 PHE 329 321 329 PHE PHE B . n 
B 1 330 GLU 330 322 330 GLU GLU B . n 
B 1 331 ASP 331 323 331 ASP ASP B . n 
B 1 332 GLU 332 324 332 GLU GLU B . n 
B 1 333 GLN 333 325 333 GLN GLN B . n 
B 1 334 GLY 334 326 334 GLY GLY B . n 
B 1 335 ARG 335 327 335 ARG ARG B . n 
B 1 336 ILE 336 328 336 ILE ILE B . n 
B 1 337 ILE 337 329 337 ILE ILE B . n 
B 1 338 ILE 338 330 338 ILE ILE B . n 
B 1 339 ASP 339 331 339 ASP ASP B . n 
B 1 340 SER 340 332 340 SER SER B . n 
B 1 341 SER 341 333 341 SER SER B . n 
B 1 342 LEU 342 334 342 LEU LEU B . n 
B 1 343 VAL 343 335 343 VAL VAL B . n 
B 1 344 HIS 344 336 344 HIS HIS B . n 
B 1 345 GLY 345 337 345 GLY GLY B . n 
B 1 346 ASN 346 338 346 ASN ASN B . n 
B 1 347 ALA 347 339 347 ALA ALA B . n 
B 1 348 PHE 348 340 348 PHE PHE B . n 
B 1 349 PRO 349 341 349 PRO PRO B . n 
B 1 350 PHE 350 342 350 PHE PHE B . n 
B 1 351 PHE 351 343 351 PHE PHE B . n 
B 1 352 PRO 352 344 352 PRO PRO B . n 
B 1 353 PRO 353 345 353 PRO PRO B . n 
B 1 354 ASP 354 346 354 ASP ASP B . n 
B 1 355 SER 355 347 355 SER SER B . n 
B 1 356 ASP 356 348 356 ASP ASP B . n 
B 1 357 GLU 357 349 357 GLU GLU B . n 
B 1 358 GLN 358 350 358 GLN GLN B . n 
B 1 359 LYS 359 351 359 LYS LYS B . n 
B 1 360 LYS 360 352 360 LYS LYS B . n 
B 1 361 LYS 361 353 361 LYS LYS B . n 
B 1 362 GLN 362 354 362 GLN GLN B . n 
B 1 363 GLU 363 355 363 GLU GLU B . n 
B 1 364 ALA 364 356 364 ALA ALA B . n 
B 1 365 ASP 365 357 365 ASP ASP B . n 
B 1 366 GLY 366 358 366 GLY GLY B . n 
B 1 367 THR 367 359 367 THR THR B . n 
B 1 368 PRO 368 360 368 PRO PRO B . n 
B 1 369 LYS 369 361 369 LYS LYS B . n 
B 1 370 ALA 370 362 370 ALA ALA B . n 
B 1 371 GLN 371 363 371 GLN GLN B . n 
B 1 372 PHE 372 364 372 PHE PHE B . n 
B 1 373 VAL 373 365 373 VAL VAL B . n 
B 1 374 ARG 374 366 374 ARG ARG B . n 
B 1 375 TRP 375 367 375 TRP TRP B . n 
B 1 376 THR 376 368 376 THR THR B . n 
B 1 377 ILE 377 369 377 ILE ILE B . n 
B 1 378 ASP 378 370 378 ASP ASP B . n 
B 1 379 PRO 379 371 379 PRO PRO B . n 
B 1 380 ARG 380 372 380 ARG ARG B . n 
B 1 381 LYS 381 373 381 LYS LYS B . n 
B 1 382 ASP 382 374 382 ASP ASP B . n 
B 1 383 ASN 383 375 383 ASN ASN B . n 
B 1 384 ASN 384 376 384 ASN ASN B . n 
B 1 385 GLU 385 377 385 GLU GLU B . n 
B 1 386 GLN 386 378 386 GLN GLN B . n 
B 1 387 LEU 387 379 387 LEU LEU B . n 
B 1 388 PRO 388 380 388 PRO PRO B . n 
B 1 389 ASP 389 381 389 ASP ASP B . n 
B 1 390 PRO 390 382 390 PRO PRO B . n 
B 1 391 GLU 391 383 391 GLU GLU B . n 
B 1 392 VAL 392 384 392 VAL VAL B . n 
B 1 393 ILE 393 385 393 ILE ILE B . n 
B 1 394 LEU 394 386 394 LEU LEU B . n 
B 1 395 ASP 395 387 395 ASP ASP B . n 
B 1 396 THR 396 388 396 THR THR B . n 
B 1 397 PRO 397 389 397 PRO PRO B . n 
B 1 398 SER 398 390 398 SER SER B . n 
B 1 399 GLU 399 391 399 GLU GLU B . n 
B 1 400 PHE 400 392 400 PHE PHE B . n 
B 1 401 PRO 401 393 401 PRO PRO B . n 
B 1 402 GLN 402 394 402 GLN GLN B . n 
B 1 403 ILE 403 395 403 ILE ILE B . n 
B 1 404 ASP 404 396 404 ASP ASP B . n 
B 1 405 ASN 405 397 405 ASN ASN B . n 
B 1 406 ARG 406 398 406 ARG ARG B . n 
B 1 407 PHE 407 399 407 PHE PHE B . n 
B 1 408 MET 408 400 408 MET MET B . n 
B 1 409 GLY 409 401 409 GLY GLY B . n 
B 1 410 VAL 410 402 410 VAL VAL B . n 
B 1 411 GLU 411 403 411 GLU GLU B . n 
B 1 412 TYR 412 404 412 TYR TYR B . n 
B 1 413 SER 413 405 413 SER SER B . n 
B 1 414 SER 414 406 414 SER SER B . n 
B 1 415 ALA 415 407 415 ALA ALA B . n 
B 1 416 PHE 416 408 416 PHE PHE B . n 
B 1 417 ILE 417 409 417 ILE ILE B . n 
B 1 418 ASN 418 410 418 ASN ASN B . n 
B 1 419 VAL 419 411 419 VAL VAL B . n 
B 1 420 PHE 420 412 420 PHE PHE B . n 
B 1 421 VAL 421 413 421 VAL VAL B . n 
B 1 422 PRO 422 414 422 PRO PRO B . n 
B 1 423 ASP 423 415 423 ASP ASP B . n 
B 1 424 ARG 424 416 424 ARG ARG B . n 
B 1 425 SER 425 417 425 SER SER B . n 
B 1 426 ASP 426 418 426 ASP ASP B . n 
B 1 427 GLY 427 419 427 GLY GLY B . n 
B 1 428 ASN 428 420 428 ASN ASN B . n 
B 1 429 LYS 429 421 429 LYS LYS B . n 
B 1 430 ASN 430 422 430 ASN ASN B . n 
B 1 431 VAL 431 423 431 VAL VAL B . n 
B 1 432 PHE 432 424 432 PHE PHE B . n 
B 1 433 GLN 433 425 433 GLN GLN B . n 
B 1 434 GLY 434 426 434 GLY GLY B . n 
B 1 435 LEU 435 427 435 LEU LEU B . n 
B 1 436 ASN 436 428 436 ASN ASN B . n 
B 1 437 GLY 437 429 437 GLY GLY B . n 
B 1 438 LEU 438 430 438 LEU LEU B . n 
B 1 439 ALA 439 431 439 ALA ALA B . n 
B 1 440 HIS 440 432 440 HIS HIS B . n 
B 1 441 TYR 441 433 441 TYR TYR B . n 
B 1 442 LYS 442 434 442 LYS LYS B . n 
B 1 443 ARG 443 435 443 ARG ARG B . n 
B 1 444 LYS 444 436 444 LYS LYS B . n 
B 1 445 GLU 445 437 445 GLU GLU B . n 
B 1 446 GLY 446 438 446 GLY GLY B . n 
B 1 447 THR 447 439 447 THR THR B . n 
B 1 448 THR 448 440 448 THR THR B . n 
B 1 449 GLU 449 441 449 GLU GLU B . n 
B 1 450 TRP 450 442 450 TRP TRP B . n 
B 1 451 TYR 451 443 451 TYR TYR B . n 
B 1 452 TYR 452 444 452 TYR TYR B . n 
B 1 453 ALA 453 445 453 ALA ALA B . n 
B 1 454 GLY 454 446 454 GLY GLY B . n 
B 1 455 ASP 455 447 455 ASP ASP B . n 
B 1 456 ASN 456 448 456 ASN ASN B . n 
B 1 457 CYS 457 449 457 CYS CYS B . n 
B 1 458 LEU 458 450 458 LEU LEU B . n 
B 1 459 ILE 459 451 459 ILE ILE B . n 
B 1 460 GLN 460 452 460 GLN GLN B . n 
B 1 461 GLU 461 453 461 GLU GLU B . n 
B 1 462 PRO 462 454 462 PRO PRO B . n 
B 1 463 VAL 463 455 463 VAL VAL B . n 
B 1 464 PHE 464 456 464 PHE PHE B . n 
B 1 465 SER 465 457 465 SER SER B . n 
B 1 466 PRO 466 458 466 PRO PRO B . n 
B 1 467 ARG 467 459 467 ARG ARG B . n 
B 1 468 SER 468 460 468 SER SER B . n 
B 1 469 LYS 469 461 469 LYS LYS B . n 
B 1 470 ASP 470 462 470 ASP ASP B . n 
B 1 471 ALA 471 463 471 ALA ALA B . n 
B 1 472 PRO 472 464 472 PRO PRO B . n 
B 1 473 GLU 473 465 473 GLU GLU B . n 
B 1 474 GLY 474 466 474 GLY GLY B . n 
B 1 475 ASP 475 467 475 ASP ASP B . n 
B 1 476 GLY 476 468 476 GLY GLY B . n 
B 1 477 PHE 477 469 477 PHE PHE B . n 
B 1 478 VAL 478 470 478 VAL VAL B . n 
B 1 479 LEU 479 471 479 LEU LEU B . n 
B 1 480 ALA 480 472 480 ALA ALA B . n 
B 1 481 ILE 481 473 481 ILE ILE B . n 
B 1 482 VAL 482 474 482 VAL VAL B . n 
B 1 483 ASP 483 475 483 ASP ASP B . n 
B 1 484 ARG 484 476 484 ARG ARG B . n 
B 1 485 LEU 485 477 485 LEU LEU B . n 
B 1 486 ASP 486 478 486 ASP ASP B . n 
B 1 487 LEU 487 479 487 LEU LEU B . n 
B 1 488 ASN 488 480 488 ASN ASN B . n 
B 1 489 ARG 489 481 489 ARG ARG B . n 
B 1 490 SER 490 482 490 SER SER B . n 
B 1 491 GLU 491 483 491 GLU GLU B . n 
B 1 492 VAL 492 484 492 VAL VAL B . n 
B 1 493 VAL 493 485 493 VAL VAL B . n 
B 1 494 VAL 494 486 494 VAL VAL B . n 
B 1 495 ILE 495 487 495 ILE ILE B . n 
B 1 496 ASP 496 488 496 ASP ASP B . n 
B 1 497 THR 497 489 497 THR THR B . n 
B 1 498 ARG 498 490 498 ARG ARG B . n 
B 1 499 ASP 499 491 499 ASP ASP B . n 
B 1 500 PHE 500 492 500 PHE PHE B . n 
B 1 501 THR 501 493 501 THR THR B . n 
B 1 502 LYS 502 494 502 LYS LYS B . n 
B 1 503 ALA 503 495 503 ALA ALA B . n 
B 1 504 VAL 504 496 504 VAL VAL B . n 
B 1 505 ALA 505 497 505 ALA ALA B . n 
B 1 506 ALA 506 498 506 ALA ALA B . n 
B 1 507 VAL 507 499 507 VAL VAL B . n 
B 1 508 GLN 508 500 508 GLN GLN B . n 
B 1 509 LEU 509 501 509 LEU LEU B . n 
B 1 510 PRO 510 502 510 PRO PRO B . n 
B 1 511 PHE 511 503 511 PHE PHE B . n 
B 1 512 ALA 512 504 512 ALA ALA B . n 
B 1 513 ILE 513 505 513 ILE ILE B . n 
B 1 514 ARG 514 506 514 ARG ARG B . n 
B 1 515 SER 515 507 515 SER SER B . n 
B 1 516 GLY 516 508 516 GLY GLY B . n 
B 1 517 ILE 517 509 517 ILE ILE B . n 
B 1 518 HIS 518 510 518 HIS HIS B . n 
B 1 519 GLY 519 511 519 GLY GLY B . n 
B 1 520 GLN 520 512 520 GLN GLN B . n 
B 1 521 TRP 521 513 521 TRP TRP B . n 
B 1 522 ILE 522 514 522 ILE ILE B . n 
B 1 523 PRO 523 515 523 PRO PRO B . n 
B 1 524 GLY 524 516 524 GLY GLY B . n 
B 1 525 GLU 525 517 525 GLU GLU B . n 
B 1 526 VAL 526 518 526 VAL VAL B . n 
B 1 527 THR 527 519 527 THR THR B . n 
B 1 528 PRO 528 520 528 PRO PRO B . n 
B 1 529 ASP 529 521 529 ASP ASP B . n 
B 1 530 PHE 530 522 530 PHE PHE B . n 
B 1 531 GLU 531 523 531 GLU GLU B . n 
B 1 532 THR 532 524 532 THR THR B . n 
B 1 533 LYS 533 525 533 LYS LYS B . n 
B 1 534 GLY 534 526 534 GLY GLY B . n 
B 1 535 LEU 535 527 535 LEU LEU B . n 
B 1 536 VAL 536 528 536 VAL VAL B . n 
B 1 537 ASP 537 529 537 ASP ASP B . n 
B 1 538 LEU 538 530 538 LEU LEU B . n 
B 1 539 PRO 539 531 539 PRO PRO B . n 
B 1 540 LYS 540 532 540 LYS LYS B . n 
B 1 541 GLU 541 533 541 GLU GLU B . n 
B 1 542 GLU 542 534 542 GLU GLU B . n 
B 1 543 HIS 543 535 543 HIS HIS B . n 
B 1 544 TRP 544 536 544 TRP TRP B . n 
B 1 545 ALA 545 537 545 ALA ALA B . n 
B 1 546 PRO 546 538 546 PRO PRO B . n 
B 1 547 LEU 547 539 547 LEU LEU B . n 
B 1 548 SER 548 540 548 SER SER B . n 
B 1 549 GLN 549 541 549 GLN GLN B . n 
B 1 550 SER 550 542 550 SER SER B . n 
B 1 551 PRO 551 543 551 PRO PRO B . n 
B 1 552 TYR 552 544 552 TYR TYR B . n 
B 1 553 ASP 553 545 553 ASP ASP B . n 
B 1 554 PRO 554 546 554 PRO PRO B . n 
B 1 555 ASP 555 547 555 ASP ASP B . n 
B 1 556 ALA 556 548 556 ALA ALA B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ACT ? ? ACT ? ? 'SUBJECT OF INVESTIGATION' ? 
2 FE2 ? ? FE2 ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 ACT 1   601  601  ACT ACT A . 
D 3 FE2 1   602  1    FE2 FE  A . 
E 2 ACT 1   601  601  ACT ACT B . 
F 3 FE2 1   602  2    FE2 FE  B . 
G 4 HOH 1   701  1797 HOH HOH A . 
G 4 HOH 2   702  1825 HOH HOH A . 
G 4 HOH 3   703  595  HOH HOH A . 
G 4 HOH 4   704  1847 HOH HOH A . 
G 4 HOH 5   705  701  HOH HOH A . 
G 4 HOH 6   706  1801 HOH HOH A . 
G 4 HOH 7   707  705  HOH HOH A . 
G 4 HOH 8   708  1829 HOH HOH A . 
G 4 HOH 9   709  447  HOH HOH A . 
G 4 HOH 10  710  1225 HOH HOH A . 
G 4 HOH 11  711  1510 HOH HOH A . 
G 4 HOH 12  712  711  HOH HOH A . 
G 4 HOH 13  713  1798 HOH HOH A . 
G 4 HOH 14  714  1340 HOH HOH A . 
G 4 HOH 15  715  1290 HOH HOH A . 
G 4 HOH 16  716  105  HOH HOH A . 
G 4 HOH 17  717  1807 HOH HOH A . 
G 4 HOH 18  718  368  HOH HOH A . 
G 4 HOH 19  719  1352 HOH HOH A . 
G 4 HOH 20  720  397  HOH HOH A . 
G 4 HOH 21  721  1068 HOH HOH A . 
G 4 HOH 22  722  154  HOH HOH A . 
G 4 HOH 23  723  1849 HOH HOH A . 
G 4 HOH 24  724  937  HOH HOH A . 
G 4 HOH 25  725  768  HOH HOH A . 
G 4 HOH 26  726  556  HOH HOH A . 
G 4 HOH 27  727  377  HOH HOH A . 
G 4 HOH 28  728  287  HOH HOH A . 
G 4 HOH 29  729  344  HOH HOH A . 
G 4 HOH 30  730  836  HOH HOH A . 
G 4 HOH 31  731  36   HOH HOH A . 
G 4 HOH 32  732  253  HOH HOH A . 
G 4 HOH 33  733  681  HOH HOH A . 
G 4 HOH 34  734  406  HOH HOH A . 
G 4 HOH 35  735  424  HOH HOH A . 
G 4 HOH 36  736  203  HOH HOH A . 
G 4 HOH 37  737  460  HOH HOH A . 
G 4 HOH 38  738  904  HOH HOH A . 
G 4 HOH 39  739  472  HOH HOH A . 
G 4 HOH 40  740  509  HOH HOH A . 
G 4 HOH 41  741  399  HOH HOH A . 
G 4 HOH 42  742  1145 HOH HOH A . 
G 4 HOH 43  743  57   HOH HOH A . 
G 4 HOH 44  744  493  HOH HOH A . 
G 4 HOH 45  745  1033 HOH HOH A . 
G 4 HOH 46  746  315  HOH HOH A . 
G 4 HOH 47  747  325  HOH HOH A . 
G 4 HOH 48  748  167  HOH HOH A . 
G 4 HOH 49  749  1782 HOH HOH A . 
G 4 HOH 50  750  970  HOH HOH A . 
G 4 HOH 51  751  161  HOH HOH A . 
G 4 HOH 52  752  248  HOH HOH A . 
G 4 HOH 53  753  473  HOH HOH A . 
G 4 HOH 54  754  704  HOH HOH A . 
G 4 HOH 55  755  417  HOH HOH A . 
G 4 HOH 56  756  300  HOH HOH A . 
G 4 HOH 57  757  949  HOH HOH A . 
G 4 HOH 58  758  978  HOH HOH A . 
G 4 HOH 59  759  496  HOH HOH A . 
G 4 HOH 60  760  975  HOH HOH A . 
G 4 HOH 61  761  721  HOH HOH A . 
G 4 HOH 62  762  1343 HOH HOH A . 
G 4 HOH 63  763  363  HOH HOH A . 
G 4 HOH 64  764  568  HOH HOH A . 
G 4 HOH 65  765  1777 HOH HOH A . 
G 4 HOH 66  766  431  HOH HOH A . 
G 4 HOH 67  767  378  HOH HOH A . 
G 4 HOH 68  768  845  HOH HOH A . 
G 4 HOH 69  769  1368 HOH HOH A . 
G 4 HOH 70  770  613  HOH HOH A . 
G 4 HOH 71  771  531  HOH HOH A . 
G 4 HOH 72  772  18   HOH HOH A . 
G 4 HOH 73  773  91   HOH HOH A . 
G 4 HOH 74  774  259  HOH HOH A . 
G 4 HOH 75  775  260  HOH HOH A . 
G 4 HOH 76  776  1325 HOH HOH A . 
G 4 HOH 77  777  185  HOH HOH A . 
G 4 HOH 78  778  876  HOH HOH A . 
G 4 HOH 79  779  561  HOH HOH A . 
G 4 HOH 80  780  1170 HOH HOH A . 
G 4 HOH 81  781  107  HOH HOH A . 
G 4 HOH 82  782  1104 HOH HOH A . 
G 4 HOH 83  783  537  HOH HOH A . 
G 4 HOH 84  784  772  HOH HOH A . 
G 4 HOH 85  785  623  HOH HOH A . 
G 4 HOH 86  786  88   HOH HOH A . 
G 4 HOH 87  787  15   HOH HOH A . 
G 4 HOH 88  788  64   HOH HOH A . 
G 4 HOH 89  789  398  HOH HOH A . 
G 4 HOH 90  790  28   HOH HOH A . 
G 4 HOH 91  791  594  HOH HOH A . 
G 4 HOH 92  792  21   HOH HOH A . 
G 4 HOH 93  793  606  HOH HOH A . 
G 4 HOH 94  794  41   HOH HOH A . 
G 4 HOH 95  795  423  HOH HOH A . 
G 4 HOH 96  796  243  HOH HOH A . 
G 4 HOH 97  797  249  HOH HOH A . 
G 4 HOH 98  798  50   HOH HOH A . 
G 4 HOH 99  799  739  HOH HOH A . 
G 4 HOH 100 800  505  HOH HOH A . 
G 4 HOH 101 801  1423 HOH HOH A . 
G 4 HOH 102 802  1157 HOH HOH A . 
G 4 HOH 103 803  7    HOH HOH A . 
G 4 HOH 104 804  691  HOH HOH A . 
G 4 HOH 105 805  120  HOH HOH A . 
G 4 HOH 106 806  477  HOH HOH A . 
G 4 HOH 107 807  601  HOH HOH A . 
G 4 HOH 108 808  237  HOH HOH A . 
G 4 HOH 109 809  1779 HOH HOH A . 
G 4 HOH 110 810  269  HOH HOH A . 
G 4 HOH 111 811  832  HOH HOH A . 
G 4 HOH 112 812  128  HOH HOH A . 
G 4 HOH 113 813  1805 HOH HOH A . 
G 4 HOH 114 814  17   HOH HOH A . 
G 4 HOH 115 815  73   HOH HOH A . 
G 4 HOH 116 816  1018 HOH HOH A . 
G 4 HOH 117 817  103  HOH HOH A . 
G 4 HOH 118 818  20   HOH HOH A . 
G 4 HOH 119 819  117  HOH HOH A . 
G 4 HOH 120 820  586  HOH HOH A . 
G 4 HOH 121 821  548  HOH HOH A . 
G 4 HOH 122 822  271  HOH HOH A . 
G 4 HOH 123 823  383  HOH HOH A . 
G 4 HOH 124 824  115  HOH HOH A . 
G 4 HOH 125 825  339  HOH HOH A . 
G 4 HOH 126 826  13   HOH HOH A . 
G 4 HOH 127 827  1841 HOH HOH A . 
G 4 HOH 128 828  723  HOH HOH A . 
G 4 HOH 129 829  565  HOH HOH A . 
G 4 HOH 130 830  158  HOH HOH A . 
G 4 HOH 131 831  569  HOH HOH A . 
G 4 HOH 132 832  345  HOH HOH A . 
G 4 HOH 133 833  139  HOH HOH A . 
G 4 HOH 134 834  435  HOH HOH A . 
G 4 HOH 135 835  141  HOH HOH A . 
G 4 HOH 136 836  162  HOH HOH A . 
G 4 HOH 137 837  89   HOH HOH A . 
G 4 HOH 138 838  323  HOH HOH A . 
G 4 HOH 139 839  599  HOH HOH A . 
G 4 HOH 140 840  133  HOH HOH A . 
G 4 HOH 141 841  270  HOH HOH A . 
G 4 HOH 142 842  221  HOH HOH A . 
G 4 HOH 143 843  680  HOH HOH A . 
G 4 HOH 144 844  119  HOH HOH A . 
G 4 HOH 145 845  212  HOH HOH A . 
G 4 HOH 146 846  34   HOH HOH A . 
G 4 HOH 147 847  801  HOH HOH A . 
G 4 HOH 148 848  507  HOH HOH A . 
G 4 HOH 149 849  1449 HOH HOH A . 
G 4 HOH 150 850  953  HOH HOH A . 
G 4 HOH 151 851  110  HOH HOH A . 
G 4 HOH 152 852  1505 HOH HOH A . 
G 4 HOH 153 853  560  HOH HOH A . 
G 4 HOH 154 854  78   HOH HOH A . 
G 4 HOH 155 855  1406 HOH HOH A . 
G 4 HOH 156 856  686  HOH HOH A . 
G 4 HOH 157 857  23   HOH HOH A . 
G 4 HOH 158 858  649  HOH HOH A . 
G 4 HOH 159 859  571  HOH HOH A . 
G 4 HOH 160 860  217  HOH HOH A . 
G 4 HOH 161 861  482  HOH HOH A . 
G 4 HOH 162 862  321  HOH HOH A . 
G 4 HOH 163 863  1126 HOH HOH A . 
G 4 HOH 164 864  410  HOH HOH A . 
G 4 HOH 165 865  136  HOH HOH A . 
G 4 HOH 166 866  207  HOH HOH A . 
G 4 HOH 167 867  515  HOH HOH A . 
G 4 HOH 168 868  551  HOH HOH A . 
G 4 HOH 169 869  558  HOH HOH A . 
G 4 HOH 170 870  854  HOH HOH A . 
G 4 HOH 171 871  913  HOH HOH A . 
G 4 HOH 172 872  495  HOH HOH A . 
G 4 HOH 173 873  268  HOH HOH A . 
G 4 HOH 174 874  265  HOH HOH A . 
G 4 HOH 175 875  59   HOH HOH A . 
G 4 HOH 176 876  1112 HOH HOH A . 
G 4 HOH 177 877  294  HOH HOH A . 
G 4 HOH 178 878  644  HOH HOH A . 
G 4 HOH 179 879  1775 HOH HOH A . 
G 4 HOH 180 880  106  HOH HOH A . 
G 4 HOH 181 881  1025 HOH HOH A . 
G 4 HOH 182 882  633  HOH HOH A . 
G 4 HOH 183 883  1819 HOH HOH A . 
G 4 HOH 184 884  787  HOH HOH A . 
G 4 HOH 185 885  820  HOH HOH A . 
G 4 HOH 186 886  94   HOH HOH A . 
G 4 HOH 187 887  261  HOH HOH A . 
G 4 HOH 188 888  1778 HOH HOH A . 
G 4 HOH 189 889  430  HOH HOH A . 
G 4 HOH 190 890  385  HOH HOH A . 
G 4 HOH 191 891  113  HOH HOH A . 
G 4 HOH 192 892  74   HOH HOH A . 
G 4 HOH 193 893  930  HOH HOH A . 
G 4 HOH 194 894  612  HOH HOH A . 
G 4 HOH 195 895  58   HOH HOH A . 
G 4 HOH 196 896  157  HOH HOH A . 
G 4 HOH 197 897  1028 HOH HOH A . 
G 4 HOH 198 898  528  HOH HOH A . 
G 4 HOH 199 899  529  HOH HOH A . 
G 4 HOH 200 900  1845 HOH HOH A . 
G 4 HOH 201 901  521  HOH HOH A . 
G 4 HOH 202 902  145  HOH HOH A . 
G 4 HOH 203 903  231  HOH HOH A . 
G 4 HOH 204 904  730  HOH HOH A . 
G 4 HOH 205 905  9    HOH HOH A . 
G 4 HOH 206 906  225  HOH HOH A . 
G 4 HOH 207 907  384  HOH HOH A . 
G 4 HOH 208 908  1794 HOH HOH A . 
G 4 HOH 209 909  152  HOH HOH A . 
G 4 HOH 210 910  824  HOH HOH A . 
G 4 HOH 211 911  489  HOH HOH A . 
G 4 HOH 212 912  172  HOH HOH A . 
G 4 HOH 213 913  401  HOH HOH A . 
G 4 HOH 214 914  31   HOH HOH A . 
G 4 HOH 215 915  10   HOH HOH A . 
G 4 HOH 216 916  367  HOH HOH A . 
G 4 HOH 217 917  453  HOH HOH A . 
G 4 HOH 218 918  732  HOH HOH A . 
G 4 HOH 219 919  197  HOH HOH A . 
G 4 HOH 220 920  603  HOH HOH A . 
G 4 HOH 221 921  874  HOH HOH A . 
G 4 HOH 222 922  372  HOH HOH A . 
G 4 HOH 223 923  1080 HOH HOH A . 
G 4 HOH 224 924  1065 HOH HOH A . 
G 4 HOH 225 925  266  HOH HOH A . 
G 4 HOH 226 926  262  HOH HOH A . 
G 4 HOH 227 927  1237 HOH HOH A . 
G 4 HOH 228 928  222  HOH HOH A . 
G 4 HOH 229 929  1542 HOH HOH A . 
G 4 HOH 230 930  1039 HOH HOH A . 
G 4 HOH 231 931  244  HOH HOH A . 
G 4 HOH 232 932  1194 HOH HOH A . 
G 4 HOH 233 933  682  HOH HOH A . 
G 4 HOH 234 934  597  HOH HOH A . 
G 4 HOH 235 935  102  HOH HOH A . 
G 4 HOH 236 936  156  HOH HOH A . 
G 4 HOH 237 937  1537 HOH HOH A . 
G 4 HOH 238 938  480  HOH HOH A . 
G 4 HOH 239 939  696  HOH HOH A . 
G 4 HOH 240 940  1530 HOH HOH A . 
G 4 HOH 241 941  22   HOH HOH A . 
G 4 HOH 242 942  1052 HOH HOH A . 
G 4 HOH 243 943  277  HOH HOH A . 
G 4 HOH 244 944  849  HOH HOH A . 
G 4 HOH 245 945  298  HOH HOH A . 
G 4 HOH 246 946  155  HOH HOH A . 
G 4 HOH 247 947  351  HOH HOH A . 
G 4 HOH 248 948  66   HOH HOH A . 
G 4 HOH 249 949  134  HOH HOH A . 
G 4 HOH 250 950  232  HOH HOH A . 
G 4 HOH 251 951  6    HOH HOH A . 
G 4 HOH 252 952  708  HOH HOH A . 
G 4 HOH 253 953  181  HOH HOH A . 
G 4 HOH 254 954  144  HOH HOH A . 
G 4 HOH 255 955  85   HOH HOH A . 
G 4 HOH 256 956  340  HOH HOH A . 
G 4 HOH 257 957  1309 HOH HOH A . 
G 4 HOH 258 958  32   HOH HOH A . 
G 4 HOH 259 959  618  HOH HOH A . 
G 4 HOH 260 960  63   HOH HOH A . 
G 4 HOH 261 961  770  HOH HOH A . 
G 4 HOH 262 962  176  HOH HOH A . 
G 4 HOH 263 963  49   HOH HOH A . 
G 4 HOH 264 964  865  HOH HOH A . 
G 4 HOH 265 965  51   HOH HOH A . 
G 4 HOH 266 966  380  HOH HOH A . 
G 4 HOH 267 967  173  HOH HOH A . 
G 4 HOH 268 968  289  HOH HOH A . 
G 4 HOH 269 969  689  HOH HOH A . 
G 4 HOH 270 970  388  HOH HOH A . 
G 4 HOH 271 971  226  HOH HOH A . 
G 4 HOH 272 972  131  HOH HOH A . 
G 4 HOH 273 973  715  HOH HOH A . 
G 4 HOH 274 974  1318 HOH HOH A . 
G 4 HOH 275 975  859  HOH HOH A . 
G 4 HOH 276 976  552  HOH HOH A . 
G 4 HOH 277 977  1776 HOH HOH A . 
G 4 HOH 278 978  433  HOH HOH A . 
G 4 HOH 279 979  1091 HOH HOH A . 
G 4 HOH 280 980  389  HOH HOH A . 
G 4 HOH 281 981  1321 HOH HOH A . 
G 4 HOH 282 982  1786 HOH HOH A . 
G 4 HOH 283 983  205  HOH HOH A . 
G 4 HOH 284 984  75   HOH HOH A . 
G 4 HOH 285 985  971  HOH HOH A . 
G 4 HOH 286 986  149  HOH HOH A . 
G 4 HOH 287 987  264  HOH HOH A . 
G 4 HOH 288 988  56   HOH HOH A . 
G 4 HOH 289 989  168  HOH HOH A . 
G 4 HOH 290 990  1032 HOH HOH A . 
G 4 HOH 291 991  273  HOH HOH A . 
G 4 HOH 292 992  428  HOH HOH A . 
G 4 HOH 293 993  769  HOH HOH A . 
G 4 HOH 294 994  195  HOH HOH A . 
G 4 HOH 295 995  319  HOH HOH A . 
G 4 HOH 296 996  1534 HOH HOH A . 
G 4 HOH 297 997  718  HOH HOH A . 
G 4 HOH 298 998  847  HOH HOH A . 
G 4 HOH 299 999  1035 HOH HOH A . 
G 4 HOH 300 1000 1057 HOH HOH A . 
G 4 HOH 301 1001 258  HOH HOH A . 
G 4 HOH 302 1002 436  HOH HOH A . 
G 4 HOH 303 1003 187  HOH HOH A . 
G 4 HOH 304 1004 1257 HOH HOH A . 
G 4 HOH 305 1005 209  HOH HOH A . 
G 4 HOH 306 1006 538  HOH HOH A . 
G 4 HOH 307 1007 112  HOH HOH A . 
G 4 HOH 308 1008 471  HOH HOH A . 
G 4 HOH 309 1009 413  HOH HOH A . 
G 4 HOH 310 1010 199  HOH HOH A . 
G 4 HOH 311 1011 163  HOH HOH A . 
G 4 HOH 312 1012 795  HOH HOH A . 
G 4 HOH 313 1013 1152 HOH HOH A . 
G 4 HOH 314 1014 488  HOH HOH A . 
G 4 HOH 315 1015 1784 HOH HOH A . 
G 4 HOH 316 1016 527  HOH HOH A . 
G 4 HOH 317 1017 194  HOH HOH A . 
G 4 HOH 318 1018 97   HOH HOH A . 
G 4 HOH 319 1019 224  HOH HOH A . 
G 4 HOH 320 1020 143  HOH HOH A . 
G 4 HOH 321 1021 798  HOH HOH A . 
G 4 HOH 322 1022 52   HOH HOH A . 
G 4 HOH 323 1023 357  HOH HOH A . 
G 4 HOH 324 1024 1071 HOH HOH A . 
G 4 HOH 325 1025 48   HOH HOH A . 
G 4 HOH 326 1026 297  HOH HOH A . 
G 4 HOH 327 1027 235  HOH HOH A . 
G 4 HOH 328 1028 229  HOH HOH A . 
G 4 HOH 329 1029 159  HOH HOH A . 
G 4 HOH 330 1030 1022 HOH HOH A . 
G 4 HOH 331 1031 1282 HOH HOH A . 
G 4 HOH 332 1032 707  HOH HOH A . 
G 4 HOH 333 1033 40   HOH HOH A . 
G 4 HOH 334 1034 880  HOH HOH A . 
G 4 HOH 335 1035 153  HOH HOH A . 
G 4 HOH 336 1036 1854 HOH HOH A . 
G 4 HOH 337 1037 500  HOH HOH A . 
G 4 HOH 338 1038 437  HOH HOH A . 
G 4 HOH 339 1039 1305 HOH HOH A . 
G 4 HOH 340 1040 879  HOH HOH A . 
G 4 HOH 341 1041 525  HOH HOH A . 
G 4 HOH 342 1042 735  HOH HOH A . 
G 4 HOH 343 1043 293  HOH HOH A . 
G 4 HOH 344 1044 1    HOH HOH A . 
G 4 HOH 345 1045 951  HOH HOH A . 
G 4 HOH 346 1046 1832 HOH HOH A . 
G 4 HOH 347 1047 228  HOH HOH A . 
G 4 HOH 348 1048 446  HOH HOH A . 
G 4 HOH 349 1049 1827 HOH HOH A . 
G 4 HOH 350 1050 177  HOH HOH A . 
G 4 HOH 351 1051 353  HOH HOH A . 
G 4 HOH 352 1052 82   HOH HOH A . 
G 4 HOH 353 1053 716  HOH HOH A . 
G 4 HOH 354 1054 246  HOH HOH A . 
G 4 HOH 355 1055 130  HOH HOH A . 
G 4 HOH 356 1056 186  HOH HOH A . 
G 4 HOH 357 1057 408  HOH HOH A . 
G 4 HOH 358 1058 45   HOH HOH A . 
G 4 HOH 359 1059 301  HOH HOH A . 
G 4 HOH 360 1060 602  HOH HOH A . 
G 4 HOH 361 1061 1780 HOH HOH A . 
G 4 HOH 362 1062 835  HOH HOH A . 
G 4 HOH 363 1063 218  HOH HOH A . 
G 4 HOH 364 1064 8    HOH HOH A . 
G 4 HOH 365 1065 366  HOH HOH A . 
G 4 HOH 366 1066 726  HOH HOH A . 
G 4 HOH 367 1067 204  HOH HOH A . 
G 4 HOH 368 1068 77   HOH HOH A . 
G 4 HOH 369 1069 125  HOH HOH A . 
G 4 HOH 370 1070 295  HOH HOH A . 
G 4 HOH 371 1071 14   HOH HOH A . 
G 4 HOH 372 1072 917  HOH HOH A . 
G 4 HOH 373 1073 719  HOH HOH A . 
G 4 HOH 374 1074 364  HOH HOH A . 
G 4 HOH 375 1075 573  HOH HOH A . 
G 4 HOH 376 1076 165  HOH HOH A . 
G 4 HOH 377 1077 563  HOH HOH A . 
G 4 HOH 378 1078 242  HOH HOH A . 
G 4 HOH 379 1079 728  HOH HOH A . 
G 4 HOH 380 1080 717  HOH HOH A . 
G 4 HOH 381 1081 329  HOH HOH A . 
G 4 HOH 382 1082 1172 HOH HOH A . 
G 4 HOH 383 1083 382  HOH HOH A . 
G 4 HOH 384 1084 336  HOH HOH A . 
G 4 HOH 385 1085 712  HOH HOH A . 
G 4 HOH 386 1086 33   HOH HOH A . 
G 4 HOH 387 1087 624  HOH HOH A . 
G 4 HOH 388 1088 961  HOH HOH A . 
G 4 HOH 389 1089 871  HOH HOH A . 
G 4 HOH 390 1090 448  HOH HOH A . 
G 4 HOH 391 1091 393  HOH HOH A . 
G 4 HOH 392 1092 738  HOH HOH A . 
G 4 HOH 393 1093 332  HOH HOH A . 
G 4 HOH 394 1094 1329 HOH HOH A . 
G 4 HOH 395 1095 127  HOH HOH A . 
G 4 HOH 396 1096 1029 HOH HOH A . 
G 4 HOH 397 1097 390  HOH HOH A . 
G 4 HOH 398 1098 79   HOH HOH A . 
G 4 HOH 399 1099 906  HOH HOH A . 
G 4 HOH 400 1100 895  HOH HOH A . 
G 4 HOH 401 1101 11   HOH HOH A . 
G 4 HOH 402 1102 239  HOH HOH A . 
G 4 HOH 403 1103 116  HOH HOH A . 
G 4 HOH 404 1104 241  HOH HOH A . 
G 4 HOH 405 1105 121  HOH HOH A . 
G 4 HOH 406 1106 1800 HOH HOH A . 
G 4 HOH 407 1107 825  HOH HOH A . 
G 4 HOH 408 1108 512  HOH HOH A . 
G 4 HOH 409 1109 1133 HOH HOH A . 
G 4 HOH 410 1110 626  HOH HOH A . 
G 4 HOH 411 1111 627  HOH HOH A . 
G 4 HOH 412 1112 306  HOH HOH A . 
G 4 HOH 413 1113 892  HOH HOH A . 
G 4 HOH 414 1114 1816 HOH HOH A . 
G 4 HOH 415 1115 191  HOH HOH A . 
G 4 HOH 416 1116 4    HOH HOH A . 
G 4 HOH 417 1117 905  HOH HOH A . 
G 4 HOH 418 1118 954  HOH HOH A . 
G 4 HOH 419 1119 683  HOH HOH A . 
G 4 HOH 420 1120 1008 HOH HOH A . 
G 4 HOH 421 1121 175  HOH HOH A . 
G 4 HOH 422 1122 312  HOH HOH A . 
G 4 HOH 423 1123 150  HOH HOH A . 
G 4 HOH 424 1124 304  HOH HOH A . 
G 4 HOH 425 1125 487  HOH HOH A . 
G 4 HOH 426 1126 1096 HOH HOH A . 
G 4 HOH 427 1127 362  HOH HOH A . 
G 4 HOH 428 1128 607  HOH HOH A . 
G 4 HOH 429 1129 379  HOH HOH A . 
G 4 HOH 430 1130 890  HOH HOH A . 
G 4 HOH 431 1131 1804 HOH HOH A . 
G 4 HOH 432 1132 625  HOH HOH A . 
G 4 HOH 433 1133 238  HOH HOH A . 
G 4 HOH 434 1134 331  HOH HOH A . 
G 4 HOH 435 1135 426  HOH HOH A . 
G 4 HOH 436 1136 675  HOH HOH A . 
G 4 HOH 437 1137 53   HOH HOH A . 
G 4 HOH 438 1138 1150 HOH HOH A . 
G 4 HOH 439 1139 282  HOH HOH A . 
G 4 HOH 440 1140 574  HOH HOH A . 
G 4 HOH 441 1141 214  HOH HOH A . 
G 4 HOH 442 1142 322  HOH HOH A . 
G 4 HOH 443 1143 806  HOH HOH A . 
G 4 HOH 444 1144 61   HOH HOH A . 
G 4 HOH 445 1145 356  HOH HOH A . 
G 4 HOH 446 1146 358  HOH HOH A . 
G 4 HOH 447 1147 564  HOH HOH A . 
G 4 HOH 448 1148 310  HOH HOH A . 
G 4 HOH 449 1149 585  HOH HOH A . 
G 4 HOH 450 1150 851  HOH HOH A . 
G 4 HOH 451 1151 1802 HOH HOH A . 
G 4 HOH 452 1152 1155 HOH HOH A . 
G 4 HOH 453 1153 1102 HOH HOH A . 
G 4 HOH 454 1154 1508 HOH HOH A . 
G 4 HOH 455 1155 292  HOH HOH A . 
G 4 HOH 456 1156 1511 HOH HOH A . 
G 4 HOH 457 1157 233  HOH HOH A . 
G 4 HOH 458 1158 1531 HOH HOH A . 
G 4 HOH 459 1159 234  HOH HOH A . 
G 4 HOH 460 1160 536  HOH HOH A . 
G 4 HOH 461 1161 365  HOH HOH A . 
G 4 HOH 462 1162 532  HOH HOH A . 
G 4 HOH 463 1163 55   HOH HOH A . 
G 4 HOH 464 1164 396  HOH HOH A . 
G 4 HOH 465 1165 147  HOH HOH A . 
G 4 HOH 466 1166 1519 HOH HOH A . 
G 4 HOH 467 1167 376  HOH HOH A . 
G 4 HOH 468 1168 12   HOH HOH A . 
G 4 HOH 469 1169 989  HOH HOH A . 
G 4 HOH 470 1170 151  HOH HOH A . 
G 4 HOH 471 1171 635  HOH HOH A . 
G 4 HOH 472 1172 111  HOH HOH A . 
G 4 HOH 473 1173 230  HOH HOH A . 
G 4 HOH 474 1174 347  HOH HOH A . 
G 4 HOH 475 1175 750  HOH HOH A . 
G 4 HOH 476 1176 646  HOH HOH A . 
G 4 HOH 477 1177 816  HOH HOH A . 
G 4 HOH 478 1178 70   HOH HOH A . 
G 4 HOH 479 1179 967  HOH HOH A . 
G 4 HOH 480 1180 202  HOH HOH A . 
G 4 HOH 481 1181 1056 HOH HOH A . 
G 4 HOH 482 1182 1820 HOH HOH A . 
G 4 HOH 483 1183 429  HOH HOH A . 
G 4 HOH 484 1184 1834 HOH HOH A . 
G 4 HOH 485 1185 1811 HOH HOH A . 
G 4 HOH 486 1186 485  HOH HOH A . 
G 4 HOH 487 1187 481  HOH HOH A . 
G 4 HOH 488 1188 374  HOH HOH A . 
G 4 HOH 489 1189 927  HOH HOH A . 
G 4 HOH 490 1190 924  HOH HOH A . 
G 4 HOH 491 1191 126  HOH HOH A . 
G 4 HOH 492 1192 254  HOH HOH A . 
G 4 HOH 493 1193 171  HOH HOH A . 
G 4 HOH 494 1194 600  HOH HOH A . 
G 4 HOH 495 1195 1095 HOH HOH A . 
G 4 HOH 496 1196 1405 HOH HOH A . 
G 4 HOH 497 1197 1850 HOH HOH A . 
G 4 HOH 498 1198 257  HOH HOH A . 
G 4 HOH 499 1199 968  HOH HOH A . 
G 4 HOH 500 1200 1848 HOH HOH A . 
G 4 HOH 501 1201 1441 HOH HOH A . 
G 4 HOH 502 1202 1822 HOH HOH A . 
G 4 HOH 503 1203 409  HOH HOH A . 
G 4 HOH 504 1204 786  HOH HOH A . 
G 4 HOH 505 1205 1634 HOH HOH A . 
G 4 HOH 506 1206 457  HOH HOH A . 
G 4 HOH 507 1207 452  HOH HOH A . 
G 4 HOH 508 1208 421  HOH HOH A . 
G 4 HOH 509 1209 823  HOH HOH A . 
G 4 HOH 510 1210 455  HOH HOH A . 
G 4 HOH 511 1211 1823 HOH HOH A . 
G 4 HOH 512 1212 1851 HOH HOH A . 
G 4 HOH 513 1213 1081 HOH HOH A . 
G 4 HOH 514 1214 779  HOH HOH A . 
G 4 HOH 515 1215 846  HOH HOH A . 
G 4 HOH 516 1216 466  HOH HOH A . 
G 4 HOH 517 1217 1600 HOH HOH A . 
G 4 HOH 518 1218 775  HOH HOH A . 
G 4 HOH 519 1219 1626 HOH HOH A . 
G 4 HOH 520 1220 1069 HOH HOH A . 
G 4 HOH 521 1221 920  HOH HOH A . 
G 4 HOH 522 1222 275  HOH HOH A . 
G 4 HOH 523 1223 1675 HOH HOH A . 
G 4 HOH 524 1224 945  HOH HOH A . 
G 4 HOH 525 1225 1494 HOH HOH A . 
G 4 HOH 526 1226 1396 HOH HOH A . 
G 4 HOH 527 1227 908  HOH HOH A . 
G 4 HOH 528 1228 1242 HOH HOH A . 
G 4 HOH 529 1229 628  HOH HOH A . 
G 4 HOH 530 1230 542  HOH HOH A . 
G 4 HOH 531 1231 754  HOH HOH A . 
G 4 HOH 532 1232 790  HOH HOH A . 
G 4 HOH 533 1233 1757 HOH HOH A . 
G 4 HOH 534 1234 450  HOH HOH A . 
G 4 HOH 535 1235 725  HOH HOH A . 
G 4 HOH 536 1236 1606 HOH HOH A . 
G 4 HOH 537 1237 1586 HOH HOH A . 
G 4 HOH 538 1238 1665 HOH HOH A . 
G 4 HOH 539 1239 522  HOH HOH A . 
G 4 HOH 540 1240 1062 HOH HOH A . 
G 4 HOH 541 1241 958  HOH HOH A . 
G 4 HOH 542 1242 1637 HOH HOH A . 
G 4 HOH 543 1243 755  HOH HOH A . 
G 4 HOH 544 1244 1289 HOH HOH A . 
G 4 HOH 545 1245 1592 HOH HOH A . 
G 4 HOH 546 1246 1016 HOH HOH A . 
G 4 HOH 547 1247 837  HOH HOH A . 
G 4 HOH 548 1248 1513 HOH HOH A . 
G 4 HOH 549 1249 1662 HOH HOH A . 
G 4 HOH 550 1250 1376 HOH HOH A . 
G 4 HOH 551 1251 355  HOH HOH A . 
G 4 HOH 552 1252 1588 HOH HOH A . 
G 4 HOH 553 1253 449  HOH HOH A . 
G 4 HOH 554 1254 1346 HOH HOH A . 
G 4 HOH 555 1255 1809 HOH HOH A . 
G 4 HOH 556 1256 1287 HOH HOH A . 
G 4 HOH 557 1257 288  HOH HOH A . 
G 4 HOH 558 1258 1617 HOH HOH A . 
G 4 HOH 559 1259 1817 HOH HOH A . 
G 4 HOH 560 1260 545  HOH HOH A . 
G 4 HOH 561 1261 922  HOH HOH A . 
G 4 HOH 562 1262 995  HOH HOH A . 
G 4 HOH 563 1263 1108 HOH HOH A . 
G 4 HOH 564 1264 1050 HOH HOH A . 
G 4 HOH 565 1265 1701 HOH HOH A . 
G 4 HOH 566 1266 1275 HOH HOH A . 
G 4 HOH 567 1267 1159 HOH HOH A . 
G 4 HOH 568 1268 486  HOH HOH A . 
G 4 HOH 569 1269 1161 HOH HOH A . 
G 4 HOH 570 1270 966  HOH HOH A . 
G 4 HOH 571 1271 943  HOH HOH A . 
G 4 HOH 572 1272 939  HOH HOH A . 
G 4 HOH 573 1273 1657 HOH HOH A . 
G 4 HOH 574 1274 1545 HOH HOH A . 
G 4 HOH 575 1275 1456 HOH HOH A . 
G 4 HOH 576 1276 1612 HOH HOH A . 
G 4 HOH 577 1277 1640 HOH HOH A . 
G 4 HOH 578 1278 1105 HOH HOH A . 
G 4 HOH 579 1279 1077 HOH HOH A . 
G 4 HOH 580 1280 1131 HOH HOH A . 
G 4 HOH 581 1281 1840 HOH HOH A . 
G 4 HOH 582 1282 1762 HOH HOH A . 
G 4 HOH 583 1283 593  HOH HOH A . 
G 4 HOH 584 1284 1171 HOH HOH A . 
G 4 HOH 585 1285 1130 HOH HOH A . 
G 4 HOH 586 1286 1000 HOH HOH A . 
G 4 HOH 587 1287 182  HOH HOH A . 
G 4 HOH 588 1288 1416 HOH HOH A . 
G 4 HOH 589 1289 263  HOH HOH A . 
G 4 HOH 590 1290 981  HOH HOH A . 
G 4 HOH 591 1291 404  HOH HOH A . 
G 4 HOH 592 1292 1299 HOH HOH A . 
G 4 HOH 593 1293 1605 HOH HOH A . 
G 4 HOH 594 1294 1835 HOH HOH A . 
G 4 HOH 595 1295 1731 HOH HOH A . 
G 4 HOH 596 1296 582  HOH HOH A . 
G 4 HOH 597 1297 759  HOH HOH A . 
G 4 HOH 598 1298 788  HOH HOH A . 
G 4 HOH 599 1299 555  HOH HOH A . 
G 4 HOH 600 1300 670  HOH HOH A . 
G 4 HOH 601 1301 1293 HOH HOH A . 
G 4 HOH 602 1302 1664 HOH HOH A . 
G 4 HOH 603 1303 991  HOH HOH A . 
G 4 HOH 604 1304 1315 HOH HOH A . 
G 4 HOH 605 1305 1551 HOH HOH A . 
G 4 HOH 606 1306 84   HOH HOH A . 
G 4 HOH 607 1307 1591 HOH HOH A . 
G 4 HOH 608 1308 620  HOH HOH A . 
G 4 HOH 609 1309 313  HOH HOH A . 
G 4 HOH 610 1310 550  HOH HOH A . 
G 4 HOH 611 1311 1688 HOH HOH A . 
G 4 HOH 612 1312 1076 HOH HOH A . 
G 4 HOH 613 1313 774  HOH HOH A . 
G 4 HOH 614 1314 811  HOH HOH A . 
G 4 HOH 615 1315 1853 HOH HOH A . 
G 4 HOH 616 1316 240  HOH HOH A . 
G 4 HOH 617 1317 814  HOH HOH A . 
G 4 HOH 618 1318 1836 HOH HOH A . 
G 4 HOH 619 1319 1824 HOH HOH A . 
G 4 HOH 620 1320 1643 HOH HOH A . 
G 4 HOH 621 1321 1630 HOH HOH A . 
G 4 HOH 622 1322 1048 HOH HOH A . 
G 4 HOH 623 1323 977  HOH HOH A . 
G 4 HOH 624 1324 350  HOH HOH A . 
G 4 HOH 625 1325 1364 HOH HOH A . 
G 4 HOH 626 1326 1694 HOH HOH A . 
G 4 HOH 627 1327 742  HOH HOH A . 
G 4 HOH 628 1328 592  HOH HOH A . 
G 4 HOH 629 1329 1013 HOH HOH A . 
G 4 HOH 630 1330 766  HOH HOH A . 
G 4 HOH 631 1331 290  HOH HOH A . 
G 4 HOH 632 1332 819  HOH HOH A . 
G 4 HOH 633 1333 1621 HOH HOH A . 
G 4 HOH 634 1334 523  HOH HOH A . 
G 4 HOH 635 1335 1516 HOH HOH A . 
G 4 HOH 636 1336 1700 HOH HOH A . 
G 4 HOH 637 1337 491  HOH HOH A . 
G 4 HOH 638 1338 305  HOH HOH A . 
G 4 HOH 639 1339 1173 HOH HOH A . 
G 4 HOH 640 1340 578  HOH HOH A . 
G 4 HOH 641 1341 938  HOH HOH A . 
G 4 HOH 642 1342 445  HOH HOH A . 
G 4 HOH 643 1343 1598 HOH HOH A . 
G 4 HOH 644 1344 135  HOH HOH A . 
G 4 HOH 645 1345 669  HOH HOH A . 
G 4 HOH 646 1346 1587 HOH HOH A . 
G 4 HOH 647 1347 935  HOH HOH A . 
G 4 HOH 648 1348 1010 HOH HOH A . 
G 4 HOH 649 1349 1668 HOH HOH A . 
G 4 HOH 650 1350 1667 HOH HOH A . 
G 4 HOH 651 1351 414  HOH HOH A . 
G 4 HOH 652 1352 1447 HOH HOH A . 
G 4 HOH 653 1353 1590 HOH HOH A . 
G 4 HOH 654 1354 878  HOH HOH A . 
G 4 HOH 655 1355 903  HOH HOH A . 
G 4 HOH 656 1356 1855 HOH HOH A . 
G 4 HOH 657 1357 547  HOH HOH A . 
G 4 HOH 658 1358 540  HOH HOH A . 
G 4 HOH 659 1359 872  HOH HOH A . 
G 4 HOH 660 1360 764  HOH HOH A . 
G 4 HOH 661 1361 1615 HOH HOH A . 
G 4 HOH 662 1362 1125 HOH HOH A . 
G 4 HOH 663 1363 1593 HOH HOH A . 
G 4 HOH 664 1364 758  HOH HOH A . 
G 4 HOH 665 1365 1619 HOH HOH A . 
G 4 HOH 666 1366 1594 HOH HOH A . 
G 4 HOH 667 1367 1471 HOH HOH A . 
G 4 HOH 668 1368 1094 HOH HOH A . 
G 4 HOH 669 1369 605  HOH HOH A . 
G 4 HOH 670 1370 572  HOH HOH A . 
G 4 HOH 671 1371 1538 HOH HOH A . 
G 4 HOH 672 1372 1815 HOH HOH A . 
G 4 HOH 673 1373 1478 HOH HOH A . 
G 4 HOH 674 1374 1543 HOH HOH A . 
G 4 HOH 675 1375 1327 HOH HOH A . 
G 4 HOH 676 1376 856  HOH HOH A . 
G 4 HOH 677 1377 1564 HOH HOH A . 
G 4 HOH 678 1378 615  HOH HOH A . 
G 4 HOH 679 1379 1059 HOH HOH A . 
G 4 HOH 680 1380 1636 HOH HOH A . 
G 4 HOH 681 1381 499  HOH HOH A . 
G 4 HOH 682 1382 1678 HOH HOH A . 
G 4 HOH 683 1383 1642 HOH HOH A . 
G 4 HOH 684 1384 698  HOH HOH A . 
G 4 HOH 685 1385 1607 HOH HOH A . 
G 4 HOH 686 1386 1623 HOH HOH A . 
G 4 HOH 687 1387 808  HOH HOH A . 
G 4 HOH 688 1388 1646 HOH HOH A . 
G 4 HOH 689 1389 1079 HOH HOH A . 
G 4 HOH 690 1390 1671 HOH HOH A . 
G 4 HOH 691 1391 1158 HOH HOH A . 
G 4 HOH 692 1392 1632 HOH HOH A . 
G 4 HOH 693 1393 869  HOH HOH A . 
G 4 HOH 694 1394 1523 HOH HOH A . 
G 4 HOH 695 1395 1319 HOH HOH A . 
G 4 HOH 696 1396 834  HOH HOH A . 
G 4 HOH 697 1397 1064 HOH HOH A . 
G 4 HOH 698 1398 1576 HOH HOH A . 
H 4 HOH 1   701  651  HOH HOH B . 
H 4 HOH 2   702  676  HOH HOH B . 
H 4 HOH 3   703  1806 HOH HOH B . 
H 4 HOH 4   704  1506 HOH HOH B . 
H 4 HOH 5   705  662  HOH HOH B . 
H 4 HOH 6   706  897  HOH HOH B . 
H 4 HOH 7   707  763  HOH HOH B . 
H 4 HOH 8   708  671  HOH HOH B . 
H 4 HOH 9   709  1307 HOH HOH B . 
H 4 HOH 10  710  285  HOH HOH B . 
H 4 HOH 11  711  617  HOH HOH B . 
H 4 HOH 12  712  999  HOH HOH B . 
H 4 HOH 13  713  661  HOH HOH B . 
H 4 HOH 14  714  1813 HOH HOH B . 
H 4 HOH 15  715  866  HOH HOH B . 
H 4 HOH 16  716  123  HOH HOH B . 
H 4 HOH 17  717  1533 HOH HOH B . 
H 4 HOH 18  718  1839 HOH HOH B . 
H 4 HOH 19  719  668  HOH HOH B . 
H 4 HOH 20  720  566  HOH HOH B . 
H 4 HOH 21  721  1004 HOH HOH B . 
H 4 HOH 22  722  720  HOH HOH B . 
H 4 HOH 23  723  1597 HOH HOH B . 
H 4 HOH 24  724  1787 HOH HOH B . 
H 4 HOH 25  725  660  HOH HOH B . 
H 4 HOH 26  726  213  HOH HOH B . 
H 4 HOH 27  727  899  HOH HOH B . 
H 4 HOH 28  728  425  HOH HOH B . 
H 4 HOH 29  729  1548 HOH HOH B . 
H 4 HOH 30  730  724  HOH HOH B . 
H 4 HOH 31  731  1387 HOH HOH B . 
H 4 HOH 32  732  706  HOH HOH B . 
H 4 HOH 33  733  276  HOH HOH B . 
H 4 HOH 34  734  296  HOH HOH B . 
H 4 HOH 35  735  1082 HOH HOH B . 
H 4 HOH 36  736  1247 HOH HOH B . 
H 4 HOH 37  737  894  HOH HOH B . 
H 4 HOH 38  738  391  HOH HOH B . 
H 4 HOH 39  739  1226 HOH HOH B . 
H 4 HOH 40  740  386  HOH HOH B . 
H 4 HOH 41  741  929  HOH HOH B . 
H 4 HOH 42  742  1821 HOH HOH B . 
H 4 HOH 43  743  546  HOH HOH B . 
H 4 HOH 44  744  714  HOH HOH B . 
H 4 HOH 45  745  169  HOH HOH B . 
H 4 HOH 46  746  517  HOH HOH B . 
H 4 HOH 47  747  636  HOH HOH B . 
H 4 HOH 48  748  757  HOH HOH B . 
H 4 HOH 49  749  1298 HOH HOH B . 
H 4 HOH 50  750  375  HOH HOH B . 
H 4 HOH 51  751  1344 HOH HOH B . 
H 4 HOH 52  752  1790 HOH HOH B . 
H 4 HOH 53  753  1017 HOH HOH B . 
H 4 HOH 54  754  703  HOH HOH B . 
H 4 HOH 55  755  767  HOH HOH B . 
H 4 HOH 56  756  283  HOH HOH B . 
H 4 HOH 57  757  926  HOH HOH B . 
H 4 HOH 58  758  1124 HOH HOH B . 
H 4 HOH 59  759  1088 HOH HOH B . 
H 4 HOH 60  760  1258 HOH HOH B . 
H 4 HOH 61  761  1490 HOH HOH B . 
H 4 HOH 62  762  1034 HOH HOH B . 
H 4 HOH 63  763  35   HOH HOH B . 
H 4 HOH 64  764  740  HOH HOH B . 
H 4 HOH 65  765  650  HOH HOH B . 
H 4 HOH 66  766  93   HOH HOH B . 
H 4 HOH 67  767  805  HOH HOH B . 
H 4 HOH 68  768  1294 HOH HOH B . 
H 4 HOH 69  769  476  HOH HOH B . 
H 4 HOH 70  770  1838 HOH HOH B . 
H 4 HOH 71  771  807  HOH HOH B . 
H 4 HOH 72  772  1424 HOH HOH B . 
H 4 HOH 73  773  354  HOH HOH B . 
H 4 HOH 74  774  687  HOH HOH B . 
H 4 HOH 75  775  256  HOH HOH B . 
H 4 HOH 76  776  1136 HOH HOH B . 
H 4 HOH 77  777  1828 HOH HOH B . 
H 4 HOH 78  778  1110 HOH HOH B . 
H 4 HOH 79  779  1249 HOH HOH B . 
H 4 HOH 80  780  211  HOH HOH B . 
H 4 HOH 81  781  1455 HOH HOH B . 
H 4 HOH 82  782  104  HOH HOH B . 
H 4 HOH 83  783  286  HOH HOH B . 
H 4 HOH 84  784  685  HOH HOH B . 
H 4 HOH 85  785  877  HOH HOH B . 
H 4 HOH 86  786  1793 HOH HOH B . 
H 4 HOH 87  787  68   HOH HOH B . 
H 4 HOH 88  788  748  HOH HOH B . 
H 4 HOH 89  789  54   HOH HOH B . 
H 4 HOH 90  790  1431 HOH HOH B . 
H 4 HOH 91  791  567  HOH HOH B . 
H 4 HOH 92  792  590  HOH HOH B . 
H 4 HOH 93  793  101  HOH HOH B . 
H 4 HOH 94  794  1846 HOH HOH B . 
H 4 HOH 95  795  702  HOH HOH B . 
H 4 HOH 96  796  782  HOH HOH B . 
H 4 HOH 97  797  570  HOH HOH B . 
H 4 HOH 98  798  792  HOH HOH B . 
H 4 HOH 99  799  27   HOH HOH B . 
H 4 HOH 100 800  998  HOH HOH B . 
H 4 HOH 101 801  797  HOH HOH B . 
H 4 HOH 102 802  252  HOH HOH B . 
H 4 HOH 103 803  611  HOH HOH B . 
H 4 HOH 104 804  38   HOH HOH B . 
H 4 HOH 105 805  279  HOH HOH B . 
H 4 HOH 106 806  405  HOH HOH B . 
H 4 HOH 107 807  709  HOH HOH B . 
H 4 HOH 108 808  174  HOH HOH B . 
H 4 HOH 109 809  324  HOH HOH B . 
H 4 HOH 110 810  247  HOH HOH B . 
H 4 HOH 111 811  122  HOH HOH B . 
H 4 HOH 112 812  535  HOH HOH B . 
H 4 HOH 113 813  700  HOH HOH B . 
H 4 HOH 114 814  170  HOH HOH B . 
H 4 HOH 115 815  1814 HOH HOH B . 
H 4 HOH 116 816  554  HOH HOH B . 
H 4 HOH 117 817  227  HOH HOH B . 
H 4 HOH 118 818  1114 HOH HOH B . 
H 4 HOH 119 819  29   HOH HOH B . 
H 4 HOH 120 820  539  HOH HOH B . 
H 4 HOH 121 821  71   HOH HOH B . 
H 4 HOH 122 822  37   HOH HOH B . 
H 4 HOH 123 823  800  HOH HOH B . 
H 4 HOH 124 824  316  HOH HOH B . 
H 4 HOH 125 825  419  HOH HOH B . 
H 4 HOH 126 826  1084 HOH HOH B . 
H 4 HOH 127 827  746  HOH HOH B . 
H 4 HOH 128 828  42   HOH HOH B . 
H 4 HOH 129 829  83   HOH HOH B . 
H 4 HOH 130 830  638  HOH HOH B . 
H 4 HOH 131 831  501  HOH HOH B . 
H 4 HOH 132 832  1192 HOH HOH B . 
H 4 HOH 133 833  699  HOH HOH B . 
H 4 HOH 134 834  299  HOH HOH B . 
H 4 HOH 135 835  630  HOH HOH B . 
H 4 HOH 136 836  1810 HOH HOH B . 
H 4 HOH 137 837  307  HOH HOH B . 
H 4 HOH 138 838  642  HOH HOH B . 
H 4 HOH 139 839  1040 HOH HOH B . 
H 4 HOH 140 840  250  HOH HOH B . 
H 4 HOH 141 841  206  HOH HOH B . 
H 4 HOH 142 842  381  HOH HOH B . 
H 4 HOH 143 843  328  HOH HOH B . 
H 4 HOH 144 844  773  HOH HOH B . 
H 4 HOH 145 845  513  HOH HOH B . 
H 4 HOH 146 846  160  HOH HOH B . 
H 4 HOH 147 847  164  HOH HOH B . 
H 4 HOH 148 848  438  HOH HOH B . 
H 4 HOH 149 849  946  HOH HOH B . 
H 4 HOH 150 850  219  HOH HOH B . 
H 4 HOH 151 851  86   HOH HOH B . 
H 4 HOH 152 852  395  HOH HOH B . 
H 4 HOH 153 853  909  HOH HOH B . 
H 4 HOH 154 854  361  HOH HOH B . 
H 4 HOH 155 855  359  HOH HOH B . 
H 4 HOH 156 856  19   HOH HOH B . 
H 4 HOH 157 857  664  HOH HOH B . 
H 4 HOH 158 858  16   HOH HOH B . 
H 4 HOH 159 859  543  HOH HOH B . 
H 4 HOH 160 860  140  HOH HOH B . 
H 4 HOH 161 861  1236 HOH HOH B . 
H 4 HOH 162 862  349  HOH HOH B . 
H 4 HOH 163 863  596  HOH HOH B . 
H 4 HOH 164 864  1783 HOH HOH B . 
H 4 HOH 165 865  887  HOH HOH B . 
H 4 HOH 166 866  416  HOH HOH B . 
H 4 HOH 167 867  697  HOH HOH B . 
H 4 HOH 168 868  90   HOH HOH B . 
H 4 HOH 169 869  65   HOH HOH B . 
H 4 HOH 170 870  1067 HOH HOH B . 
H 4 HOH 171 871  208  HOH HOH B . 
H 4 HOH 172 872  645  HOH HOH B . 
H 4 HOH 173 873  741  HOH HOH B . 
H 4 HOH 174 874  30   HOH HOH B . 
H 4 HOH 175 875  308  HOH HOH B . 
H 4 HOH 176 876  1134 HOH HOH B . 
H 4 HOH 177 877  189  HOH HOH B . 
H 4 HOH 178 878  334  HOH HOH B . 
H 4 HOH 179 879  1833 HOH HOH B . 
H 4 HOH 180 880  465  HOH HOH B . 
H 4 HOH 181 881  3    HOH HOH B . 
H 4 HOH 182 882  451  HOH HOH B . 
H 4 HOH 183 883  514  HOH HOH B . 
H 4 HOH 184 884  196  HOH HOH B . 
H 4 HOH 185 885  1391 HOH HOH B . 
H 4 HOH 186 886  371  HOH HOH B . 
H 4 HOH 187 887  534  HOH HOH B . 
H 4 HOH 188 888  342  HOH HOH B . 
H 4 HOH 189 889  1213 HOH HOH B . 
H 4 HOH 190 890  108  HOH HOH B . 
H 4 HOH 191 891  553  HOH HOH B . 
H 4 HOH 192 892  659  HOH HOH B . 
H 4 HOH 193 893  751  HOH HOH B . 
H 4 HOH 194 894  656  HOH HOH B . 
H 4 HOH 195 895  891  HOH HOH B . 
H 4 HOH 196 896  69   HOH HOH B . 
H 4 HOH 197 897  557  HOH HOH B . 
H 4 HOH 198 898  5    HOH HOH B . 
H 4 HOH 199 899  87   HOH HOH B . 
H 4 HOH 200 900  794  HOH HOH B . 
H 4 HOH 201 901  46   HOH HOH B . 
H 4 HOH 202 902  98   HOH HOH B . 
H 4 HOH 203 903  427  HOH HOH B . 
H 4 HOH 204 904  236  HOH HOH B . 
H 4 HOH 205 905  544  HOH HOH B . 
H 4 HOH 206 906  663  HOH HOH B . 
H 4 HOH 207 907  1842 HOH HOH B . 
H 4 HOH 208 908  677  HOH HOH B . 
H 4 HOH 209 909  1844 HOH HOH B . 
H 4 HOH 210 910  402  HOH HOH B . 
H 4 HOH 211 911  124  HOH HOH B . 
H 4 HOH 212 912  403  HOH HOH B . 
H 4 HOH 213 913  1831 HOH HOH B . 
H 4 HOH 214 914  92   HOH HOH B . 
H 4 HOH 215 915  370  HOH HOH B . 
H 4 HOH 216 916  411  HOH HOH B . 
H 4 HOH 217 917  692  HOH HOH B . 
H 4 HOH 218 918  1781 HOH HOH B . 
H 4 HOH 219 919  503  HOH HOH B . 
H 4 HOH 220 920  533  HOH HOH B . 
H 4 HOH 221 921  1379 HOH HOH B . 
H 4 HOH 222 922  784  HOH HOH B . 
H 4 HOH 223 923  575  HOH HOH B . 
H 4 HOH 224 924  1278 HOH HOH B . 
H 4 HOH 225 925  220  HOH HOH B . 
H 4 HOH 226 926  341  HOH HOH B . 
H 4 HOH 227 927  166  HOH HOH B . 
H 4 HOH 228 928  478  HOH HOH B . 
H 4 HOH 229 929  1058 HOH HOH B . 
H 4 HOH 230 930  1437 HOH HOH B . 
H 4 HOH 231 931  25   HOH HOH B . 
H 4 HOH 232 932  461  HOH HOH B . 
H 4 HOH 233 933  327  HOH HOH B . 
H 4 HOH 234 934  506  HOH HOH B . 
H 4 HOH 235 935  469  HOH HOH B . 
H 4 HOH 236 936  1818 HOH HOH B . 
H 4 HOH 237 937  210  HOH HOH B . 
H 4 HOH 238 938  412  HOH HOH B . 
H 4 HOH 239 939  245  HOH HOH B . 
H 4 HOH 240 940  1090 HOH HOH B . 
H 4 HOH 241 941  853  HOH HOH B . 
H 4 HOH 242 942  255  HOH HOH B . 
H 4 HOH 243 943  456  HOH HOH B . 
H 4 HOH 244 944  1316 HOH HOH B . 
H 4 HOH 245 945  952  HOH HOH B . 
H 4 HOH 246 946  387  HOH HOH B . 
H 4 HOH 247 947  137  HOH HOH B . 
H 4 HOH 248 948  710  HOH HOH B . 
H 4 HOH 249 949  516  HOH HOH B . 
H 4 HOH 250 950  326  HOH HOH B . 
H 4 HOH 251 951  420  HOH HOH B . 
H 4 HOH 252 952  665  HOH HOH B . 
H 4 HOH 253 953  747  HOH HOH B . 
H 4 HOH 254 954  418  HOH HOH B . 
H 4 HOH 255 955  444  HOH HOH B . 
H 4 HOH 256 956  1109 HOH HOH B . 
H 4 HOH 257 957  80   HOH HOH B . 
H 4 HOH 258 958  1774 HOH HOH B . 
H 4 HOH 259 959  1347 HOH HOH B . 
H 4 HOH 260 960  530  HOH HOH B . 
H 4 HOH 261 961  95   HOH HOH B . 
H 4 HOH 262 962  1093 HOH HOH B . 
H 4 HOH 263 963  193  HOH HOH B . 
H 4 HOH 264 964  762  HOH HOH B . 
H 4 HOH 265 965  335  HOH HOH B . 
H 4 HOH 266 966  76   HOH HOH B . 
H 4 HOH 267 967  215  HOH HOH B . 
H 4 HOH 268 968  280  HOH HOH B . 
H 4 HOH 269 969  251  HOH HOH B . 
H 4 HOH 270 970  338  HOH HOH B . 
H 4 HOH 271 971  188  HOH HOH B . 
H 4 HOH 272 972  581  HOH HOH B . 
H 4 HOH 273 973  333  HOH HOH B . 
H 4 HOH 274 974  925  HOH HOH B . 
H 4 HOH 275 975  610  HOH HOH B . 
H 4 HOH 276 976  511  HOH HOH B . 
H 4 HOH 277 977  674  HOH HOH B . 
H 4 HOH 278 978  609  HOH HOH B . 
H 4 HOH 279 979  1288 HOH HOH B . 
H 4 HOH 280 980  468  HOH HOH B . 
H 4 HOH 281 981  284  HOH HOH B . 
H 4 HOH 282 982  1363 HOH HOH B . 
H 4 HOH 283 983  179  HOH HOH B . 
H 4 HOH 284 984  684  HOH HOH B . 
H 4 HOH 285 985  1799 HOH HOH B . 
H 4 HOH 286 986  1763 HOH HOH B . 
H 4 HOH 287 987  587  HOH HOH B . 
H 4 HOH 288 988  443  HOH HOH B . 
H 4 HOH 289 989  138  HOH HOH B . 
H 4 HOH 290 990  462  HOH HOH B . 
H 4 HOH 291 991  216  HOH HOH B . 
H 4 HOH 292 992  142  HOH HOH B . 
H 4 HOH 293 993  60   HOH HOH B . 
H 4 HOH 294 994  804  HOH HOH B . 
H 4 HOH 295 995  973  HOH HOH B . 
H 4 HOH 296 996  591  HOH HOH B . 
H 4 HOH 297 997  1792 HOH HOH B . 
H 4 HOH 298 998  1803 HOH HOH B . 
H 4 HOH 299 999  274  HOH HOH B . 
H 4 HOH 300 1000 200  HOH HOH B . 
H 4 HOH 301 1001 1221 HOH HOH B . 
H 4 HOH 302 1002 1002 HOH HOH B . 
H 4 HOH 303 1003 352  HOH HOH B . 
H 4 HOH 304 1004 291  HOH HOH B . 
H 4 HOH 305 1005 467  HOH HOH B . 
H 4 HOH 306 1006 1791 HOH HOH B . 
H 4 HOH 307 1007 81   HOH HOH B . 
H 4 HOH 308 1008 67   HOH HOH B . 
H 4 HOH 309 1009 223  HOH HOH B . 
H 4 HOH 310 1010 857  HOH HOH B . 
H 4 HOH 311 1011 777  HOH HOH B . 
H 4 HOH 312 1012 1541 HOH HOH B . 
H 4 HOH 313 1013 148  HOH HOH B . 
H 4 HOH 314 1014 896  HOH HOH B . 
H 4 HOH 315 1015 198  HOH HOH B . 
H 4 HOH 316 1016 348  HOH HOH B . 
H 4 HOH 317 1017 309  HOH HOH B . 
H 4 HOH 318 1018 1371 HOH HOH B . 
H 4 HOH 319 1019 918  HOH HOH B . 
H 4 HOH 320 1020 639  HOH HOH B . 
H 4 HOH 321 1021 281  HOH HOH B . 
H 4 HOH 322 1022 893  HOH HOH B . 
H 4 HOH 323 1023 881  HOH HOH B . 
H 4 HOH 324 1024 497  HOH HOH B . 
H 4 HOH 325 1025 272  HOH HOH B . 
H 4 HOH 326 1026 459  HOH HOH B . 
H 4 HOH 327 1027 915  HOH HOH B . 
H 4 HOH 328 1028 479  HOH HOH B . 
H 4 HOH 329 1029 850  HOH HOH B . 
H 4 HOH 330 1030 1297 HOH HOH B . 
H 4 HOH 331 1031 2    HOH HOH B . 
H 4 HOH 332 1032 902  HOH HOH B . 
H 4 HOH 333 1033 439  HOH HOH B . 
H 4 HOH 334 1034 44   HOH HOH B . 
H 4 HOH 335 1035 475  HOH HOH B . 
H 4 HOH 336 1036 688  HOH HOH B . 
H 4 HOH 337 1037 1128 HOH HOH B . 
H 4 HOH 338 1038 1808 HOH HOH B . 
H 4 HOH 339 1039 518  HOH HOH B . 
H 4 HOH 340 1040 369  HOH HOH B . 
H 4 HOH 341 1041 1336 HOH HOH B . 
H 4 HOH 342 1042 870  HOH HOH B . 
H 4 HOH 343 1043 962  HOH HOH B . 
H 4 HOH 344 1044 114  HOH HOH B . 
H 4 HOH 345 1045 490  HOH HOH B . 
H 4 HOH 346 1046 1785 HOH HOH B . 
H 4 HOH 347 1047 583  HOH HOH B . 
H 4 HOH 348 1048 584  HOH HOH B . 
H 4 HOH 349 1049 1789 HOH HOH B . 
H 4 HOH 350 1050 793  HOH HOH B . 
H 4 HOH 351 1051 1078 HOH HOH B . 
H 4 HOH 352 1052 483  HOH HOH B . 
H 4 HOH 353 1053 604  HOH HOH B . 
H 4 HOH 354 1054 184  HOH HOH B . 
H 4 HOH 355 1055 278  HOH HOH B . 
H 4 HOH 356 1056 744  HOH HOH B . 
H 4 HOH 357 1057 129  HOH HOH B . 
H 4 HOH 358 1058 1355 HOH HOH B . 
H 4 HOH 359 1059 109  HOH HOH B . 
H 4 HOH 360 1060 1197 HOH HOH B . 
H 4 HOH 361 1061 1142 HOH HOH B . 
H 4 HOH 362 1062 729  HOH HOH B . 
H 4 HOH 363 1063 589  HOH HOH B . 
H 4 HOH 364 1064 43   HOH HOH B . 
H 4 HOH 365 1065 1655 HOH HOH B . 
H 4 HOH 366 1066 311  HOH HOH B . 
H 4 HOH 367 1067 392  HOH HOH B . 
H 4 HOH 368 1068 888  HOH HOH B . 
H 4 HOH 369 1069 693  HOH HOH B . 
H 4 HOH 370 1070 654  HOH HOH B . 
H 4 HOH 371 1071 118  HOH HOH B . 
H 4 HOH 372 1072 1111 HOH HOH B . 
H 4 HOH 373 1073 422  HOH HOH B . 
H 4 HOH 374 1074 26   HOH HOH B . 
H 4 HOH 375 1075 1304 HOH HOH B . 
H 4 HOH 376 1076 1063 HOH HOH B . 
H 4 HOH 377 1077 178  HOH HOH B . 
H 4 HOH 378 1078 394  HOH HOH B . 
H 4 HOH 379 1079 343  HOH HOH B . 
H 4 HOH 380 1080 778  HOH HOH B . 
H 4 HOH 381 1081 432  HOH HOH B . 
H 4 HOH 382 1082 796  HOH HOH B . 
H 4 HOH 383 1083 541  HOH HOH B . 
H 4 HOH 384 1084 442  HOH HOH B . 
H 4 HOH 385 1085 24   HOH HOH B . 
H 4 HOH 386 1086 180  HOH HOH B . 
H 4 HOH 387 1087 858  HOH HOH B . 
H 4 HOH 388 1088 657  HOH HOH B . 
H 4 HOH 389 1089 454  HOH HOH B . 
H 4 HOH 390 1090 484  HOH HOH B . 
H 4 HOH 391 1091 415  HOH HOH B . 
H 4 HOH 392 1092 96   HOH HOH B . 
H 4 HOH 393 1093 330  HOH HOH B . 
H 4 HOH 394 1094 1256 HOH HOH B . 
H 4 HOH 395 1095 1469 HOH HOH B . 
H 4 HOH 396 1096 780  HOH HOH B . 
H 4 HOH 397 1097 400  HOH HOH B . 
H 4 HOH 398 1098 822  HOH HOH B . 
H 4 HOH 399 1099 885  HOH HOH B . 
H 4 HOH 400 1100 498  HOH HOH B . 
H 4 HOH 401 1101 267  HOH HOH B . 
H 4 HOH 402 1102 974  HOH HOH B . 
H 4 HOH 403 1103 183  HOH HOH B . 
H 4 HOH 404 1104 907  HOH HOH B . 
H 4 HOH 405 1105 504  HOH HOH B . 
H 4 HOH 406 1106 1417 HOH HOH B . 
H 4 HOH 407 1107 1027 HOH HOH B . 
H 4 HOH 408 1108 100  HOH HOH B . 
H 4 HOH 409 1109 320  HOH HOH B . 
H 4 HOH 410 1110 1788 HOH HOH B . 
H 4 HOH 411 1111 201  HOH HOH B . 
H 4 HOH 412 1112 695  HOH HOH B . 
H 4 HOH 413 1113 508  HOH HOH B . 
H 4 HOH 414 1114 1795 HOH HOH B . 
H 4 HOH 415 1115 464  HOH HOH B . 
H 4 HOH 416 1116 1165 HOH HOH B . 
H 4 HOH 417 1117 1210 HOH HOH B . 
H 4 HOH 418 1118 302  HOH HOH B . 
H 4 HOH 419 1119 621  HOH HOH B . 
H 4 HOH 420 1120 190  HOH HOH B . 
H 4 HOH 421 1121 883  HOH HOH B . 
H 4 HOH 422 1122 1005 HOH HOH B . 
H 4 HOH 423 1123 1507 HOH HOH B . 
H 4 HOH 424 1124 407  HOH HOH B . 
H 4 HOH 425 1125 99   HOH HOH B . 
H 4 HOH 426 1126 637  HOH HOH B . 
H 4 HOH 427 1127 1092 HOH HOH B . 
H 4 HOH 428 1128 1199 HOH HOH B . 
H 4 HOH 429 1129 1852 HOH HOH B . 
H 4 HOH 430 1130 346  HOH HOH B . 
H 4 HOH 431 1131 749  HOH HOH B . 
H 4 HOH 432 1132 360  HOH HOH B . 
H 4 HOH 433 1133 303  HOH HOH B . 
H 4 HOH 434 1134 947  HOH HOH B . 
H 4 HOH 435 1135 948  HOH HOH B . 
H 4 HOH 436 1136 562  HOH HOH B . 
H 4 HOH 437 1137 502  HOH HOH B . 
H 4 HOH 438 1138 1631 HOH HOH B . 
H 4 HOH 439 1139 964  HOH HOH B . 
H 4 HOH 440 1140 132  HOH HOH B . 
H 4 HOH 441 1141 580  HOH HOH B . 
H 4 HOH 442 1142 492  HOH HOH B . 
H 4 HOH 443 1143 1201 HOH HOH B . 
H 4 HOH 444 1144 474  HOH HOH B . 
H 4 HOH 445 1145 632  HOH HOH B . 
H 4 HOH 446 1146 1320 HOH HOH B . 
H 4 HOH 447 1147 1460 HOH HOH B . 
H 4 HOH 448 1148 1826 HOH HOH B . 
H 4 HOH 449 1149 655  HOH HOH B . 
H 4 HOH 450 1150 629  HOH HOH B . 
H 4 HOH 451 1151 1412 HOH HOH B . 
H 4 HOH 452 1152 1020 HOH HOH B . 
H 4 HOH 453 1153 736  HOH HOH B . 
H 4 HOH 454 1154 1073 HOH HOH B . 
H 4 HOH 455 1155 588  HOH HOH B . 
H 4 HOH 456 1156 690  HOH HOH B . 
H 4 HOH 457 1157 1306 HOH HOH B . 
H 4 HOH 458 1158 658  HOH HOH B . 
H 4 HOH 459 1159 39   HOH HOH B . 
H 4 HOH 460 1160 727  HOH HOH B . 
H 4 HOH 461 1161 972  HOH HOH B . 
H 4 HOH 462 1162 955  HOH HOH B . 
H 4 HOH 463 1163 1205 HOH HOH B . 
H 4 HOH 464 1164 694  HOH HOH B . 
H 4 HOH 465 1165 864  HOH HOH B . 
H 4 HOH 466 1166 983  HOH HOH B . 
H 4 HOH 467 1167 1268 HOH HOH B . 
H 4 HOH 468 1168 318  HOH HOH B . 
H 4 HOH 469 1169 1383 HOH HOH B . 
H 4 HOH 470 1170 1046 HOH HOH B . 
H 4 HOH 471 1171 1129 HOH HOH B . 
H 4 HOH 472 1172 510  HOH HOH B . 
H 4 HOH 473 1173 969  HOH HOH B . 
H 4 HOH 474 1174 1582 HOH HOH B . 
H 4 HOH 475 1175 1603 HOH HOH B . 
H 4 HOH 476 1176 1654 HOH HOH B . 
H 4 HOH 477 1177 791  HOH HOH B . 
H 4 HOH 478 1178 1215 HOH HOH B . 
H 4 HOH 479 1179 1674 HOH HOH B . 
H 4 HOH 480 1180 1138 HOH HOH B . 
H 4 HOH 481 1181 1167 HOH HOH B . 
H 4 HOH 482 1182 1164 HOH HOH B . 
H 4 HOH 483 1183 1021 HOH HOH B . 
H 4 HOH 484 1184 1625 HOH HOH B . 
H 4 HOH 485 1185 1409 HOH HOH B . 
H 4 HOH 486 1186 765  HOH HOH B . 
H 4 HOH 487 1187 1589 HOH HOH B . 
H 4 HOH 488 1188 1526 HOH HOH B . 
H 4 HOH 489 1189 1139 HOH HOH B . 
H 4 HOH 490 1190 1718 HOH HOH B . 
H 4 HOH 491 1191 373  HOH HOH B . 
H 4 HOH 492 1192 653  HOH HOH B . 
H 4 HOH 493 1193 1602 HOH HOH B . 
H 4 HOH 494 1194 1647 HOH HOH B . 
H 4 HOH 495 1195 1561 HOH HOH B . 
H 4 HOH 496 1196 959  HOH HOH B . 
H 4 HOH 497 1197 1676 HOH HOH B . 
H 4 HOH 498 1198 62   HOH HOH B . 
H 4 HOH 499 1199 731  HOH HOH B . 
H 4 HOH 500 1200 1752 HOH HOH B . 
H 4 HOH 501 1201 549  HOH HOH B . 
H 4 HOH 502 1202 672  HOH HOH B . 
H 4 HOH 503 1203 1796 HOH HOH B . 
H 4 HOH 504 1204 1430 HOH HOH B . 
H 4 HOH 505 1205 733  HOH HOH B . 
H 4 HOH 506 1206 860  HOH HOH B . 
H 4 HOH 507 1207 1486 HOH HOH B . 
H 4 HOH 508 1208 1322 HOH HOH B . 
H 4 HOH 509 1209 1812 HOH HOH B . 
H 4 HOH 510 1210 1381 HOH HOH B . 
H 4 HOH 511 1211 844  HOH HOH B . 
H 4 HOH 512 1212 1398 HOH HOH B . 
H 4 HOH 513 1213 1241 HOH HOH B . 
H 4 HOH 514 1214 886  HOH HOH B . 
H 4 HOH 515 1215 986  HOH HOH B . 
H 4 HOH 516 1216 831  HOH HOH B . 
H 4 HOH 517 1217 1276 HOH HOH B . 
H 4 HOH 518 1218 1601 HOH HOH B . 
H 4 HOH 519 1219 1023 HOH HOH B . 
H 4 HOH 520 1220 1562 HOH HOH B . 
H 4 HOH 521 1221 1837 HOH HOH B . 
H 4 HOH 522 1222 1633 HOH HOH B . 
H 4 HOH 523 1223 1720 HOH HOH B . 
H 4 HOH 524 1224 855  HOH HOH B . 
H 4 HOH 525 1225 1162 HOH HOH B . 
H 4 HOH 526 1226 1070 HOH HOH B . 
H 4 HOH 527 1227 884  HOH HOH B . 
H 4 HOH 528 1228 1672 HOH HOH B . 
H 4 HOH 529 1229 1604 HOH HOH B . 
H 4 HOH 530 1230 985  HOH HOH B . 
H 4 HOH 531 1231 434  HOH HOH B . 
H 4 HOH 532 1232 470  HOH HOH B . 
H 4 HOH 533 1233 652  HOH HOH B . 
H 4 HOH 534 1234 838  HOH HOH B . 
H 4 HOH 535 1235 1212 HOH HOH B . 
H 4 HOH 536 1236 1737 HOH HOH B . 
H 4 HOH 537 1237 1596 HOH HOH B . 
H 4 HOH 538 1238 1830 HOH HOH B . 
H 4 HOH 539 1239 1673 HOH HOH B . 
H 4 HOH 540 1240 1444 HOH HOH B . 
H 4 HOH 541 1241 317  HOH HOH B . 
H 4 HOH 542 1242 1198 HOH HOH B . 
H 4 HOH 543 1243 1645 HOH HOH B . 
H 4 HOH 544 1244 1014 HOH HOH B . 
H 4 HOH 545 1245 1440 HOH HOH B . 
H 4 HOH 546 1246 994  HOH HOH B . 
H 4 HOH 547 1247 337  HOH HOH B . 
H 4 HOH 548 1248 1609 HOH HOH B . 
H 4 HOH 549 1249 785  HOH HOH B . 
H 4 HOH 550 1250 1036 HOH HOH B . 
H 4 HOH 551 1251 1677 HOH HOH B . 
H 4 HOH 552 1252 1658 HOH HOH B . 
H 4 HOH 553 1253 1610 HOH HOH B . 
H 4 HOH 554 1254 1614 HOH HOH B . 
H 4 HOH 555 1255 936  HOH HOH B . 
H 4 HOH 556 1256 526  HOH HOH B . 
H 4 HOH 557 1257 1843 HOH HOH B . 
H 4 HOH 558 1258 598  HOH HOH B . 
H 4 HOH 559 1259 799  HOH HOH B . 
H 4 HOH 560 1260 1616 HOH HOH B . 
H 4 HOH 561 1261 616  HOH HOH B . 
H 4 HOH 562 1262 900  HOH HOH B . 
H 4 HOH 563 1263 634  HOH HOH B . 
H 4 HOH 564 1264 640  HOH HOH B . 
H 4 HOH 565 1265 1106 HOH HOH B . 
H 4 HOH 566 1266 919  HOH HOH B . 
H 4 HOH 567 1267 1620 HOH HOH B . 
H 4 HOH 568 1268 608  HOH HOH B . 
H 4 HOH 569 1269 842  HOH HOH B . 
H 4 HOH 570 1270 840  HOH HOH B . 
H 4 HOH 571 1271 576  HOH HOH B . 
H 4 HOH 572 1272 1085 HOH HOH B . 
H 4 HOH 573 1273 1641 HOH HOH B . 
H 4 HOH 574 1274 1758 HOH HOH B . 
H 4 HOH 575 1275 1624 HOH HOH B . 
H 4 HOH 576 1276 1595 HOH HOH B . 
H 4 HOH 577 1277 622  HOH HOH B . 
H 4 HOH 578 1278 72   HOH HOH B . 
H 4 HOH 579 1279 1571 HOH HOH B . 
H 4 HOH 580 1280 440  HOH HOH B . 
H 4 HOH 581 1281 1652 HOH HOH B . 
H 4 HOH 582 1282 722  HOH HOH B . 
H 4 HOH 583 1283 862  HOH HOH B . 
H 4 HOH 584 1284 1012 HOH HOH B . 
H 4 HOH 585 1285 713  HOH HOH B . 
H 4 HOH 586 1286 666  HOH HOH B . 
H 4 HOH 587 1287 1476 HOH HOH B . 
H 4 HOH 588 1288 1659 HOH HOH B . 
H 4 HOH 589 1289 1698 HOH HOH B . 
H 4 HOH 590 1290 579  HOH HOH B . 
H 4 HOH 591 1291 494  HOH HOH B . 
H 4 HOH 592 1292 1574 HOH HOH B . 
H 4 HOH 593 1293 1146 HOH HOH B . 
H 4 HOH 594 1294 1577 HOH HOH B . 
H 4 HOH 595 1295 1649 HOH HOH B . 
H 4 HOH 596 1296 815  HOH HOH B . 
H 4 HOH 597 1297 667  HOH HOH B . 
H 4 HOH 598 1298 1608 HOH HOH B . 
H 4 HOH 599 1299 841  HOH HOH B . 
H 4 HOH 600 1300 1415 HOH HOH B . 
H 4 HOH 601 1301 743  HOH HOH B . 
H 4 HOH 602 1302 1613 HOH HOH B . 
H 4 HOH 603 1303 1254 HOH HOH B . 
H 4 HOH 604 1304 1756 HOH HOH B . 
H 4 HOH 605 1305 1202 HOH HOH B . 
H 4 HOH 606 1306 934  HOH HOH B . 
H 4 HOH 607 1307 1408 HOH HOH B . 
H 4 HOH 608 1308 1354 HOH HOH B . 
H 4 HOH 609 1309 1622 HOH HOH B . 
H 4 HOH 610 1310 1174 HOH HOH B . 
H 4 HOH 611 1311 1695 HOH HOH B . 
H 4 HOH 612 1312 1771 HOH HOH B . 
H 4 HOH 613 1313 993  HOH HOH B . 
H 4 HOH 614 1314 1169 HOH HOH B . 
H 4 HOH 615 1315 1744 HOH HOH B . 
H 4 HOH 616 1316 1760 HOH HOH B . 
H 4 HOH 617 1317 914  HOH HOH B . 
H 4 HOH 618 1318 1397 HOH HOH B . 
H 4 HOH 619 1319 1653 HOH HOH B . 
H 4 HOH 620 1320 1629 HOH HOH B . 
H 4 HOH 621 1321 1666 HOH HOH B . 
H 4 HOH 622 1322 1644 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   100.336 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9G88 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     72.155 
_cell.length_a_esd                 ? 
_cell.length_b                     85.957 
_cell.length_b_esd                 ? 
_cell.length_c                     93.87 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9G88 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9G88 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.28 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.96 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20%w/vPolyethyleneglycol 3,350 200mM Lithiumacetate 30% GOL' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-06-05 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03322 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, DESY BEAMLINE P11' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03322 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   P11 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9G88 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.40 
_reflns.d_resolution_low                               46.17 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     216121 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.073 
_reflns.pdbx_Rpim_I_all                                0.048 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.054 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
7.67 46.17 ? ? ? ? ? ? 1422 ? ? ? ? ? ? ? ? ? ? ? 3.9 ? ? ? 0.043 0.029 ? 1 1 0.988 ? ? ? ? 0.031 ? ? ? ? ? ? ? ? ? 
1.40 1.42  ? ? ? ? ? ? 8729 ? ? ? ? ? ? ? ? ? ? ? 3.1 ? ? ? 1.325 0.851 ? 2 1 0.432 ? ? ? ? 1.005 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            -0.299 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            -0.363 
_refine.aniso_B[2][2]                            0.555 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -0.116 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               21.317 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.975 
_refine.correlation_coeff_Fo_to_Fc_free          0.965 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9G88 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.400 
_refine.ls_d_res_low                             46.17 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     215828 
_refine.ls_number_reflns_R_free                  10853 
_refine.ls_number_reflns_R_work                  204975 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.547 
_refine.ls_percent_reflns_R_free                 5.029 
_refine.ls_R_factor_all                          0.169 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1929 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1676 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.058 
_refine.pdbx_overall_ESU_R_Free                  0.061 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.246 
_refine.overall_SU_ML                            0.047 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.400 
_refine_hist.d_res_low                        46.17 
_refine_hist.number_atoms_solvent             1320 
_refine_hist.number_atoms_total               9750 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8420 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         10 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  0.012  8734  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 1.966  1.830  11898 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.241  5.000  1058  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 8.321  5.000  56    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 12.682 10.000 1366  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.747 10.000 432   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.128  0.200  1223  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.012  0.020  7024  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.197  0.200  4018  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.307  0.200  5873  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.113  0.200  1061  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.173  0.200  48    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.172  0.200  29    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.690  1.825  4225  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.295  3.282  5284  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.997  2.042  4509  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.246  3.640  6614  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.241  21.955 13889 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 0.067  0.050  17705 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.06749 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.06749 ? 0.05009 2 'Local ncs' ? A ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.400 1.436 . . 710 12700 82.3862  . . . . 0.310 . . . . . . . . . . . 0.312 
'X-RAY DIFFRACTION' 1.436 1.476 . . 765 14781 97.5282  . . . . 0.287 . . . . . . . . . . . 0.291 
'X-RAY DIFFRACTION' 1.476 1.518 . . 794 14538 99.3649  . . . . 0.251 . . . . . . . . . . . 0.261 
'X-RAY DIFFRACTION' 1.518 1.565 . . 758 14204 99.4351  . . . . 0.235 . . . . . . . . . . . 0.257 
'X-RAY DIFFRACTION' 1.565 1.616 . . 700 13681 99.0768  . . . . 0.205 . . . . . . . . . . . 0.220 
'X-RAY DIFFRACTION' 1.616 1.673 . . 699 13208 98.5683  . . . . 0.190 . . . . . . . . . . . 0.223 
'X-RAY DIFFRACTION' 1.673 1.736 . . 654 12578 97.5308  . . . . 0.183 . . . . . . . . . . . 0.202 
'X-RAY DIFFRACTION' 1.736 1.807 . . 617 12043 96.6043  . . . . 0.170 . . . . . . . . . . . 0.208 
'X-RAY DIFFRACTION' 1.807 1.887 . . 657 11882 99.7772  . . . . 0.165 . . . . . . . . . . . 0.209 
'X-RAY DIFFRACTION' 1.887 1.979 . . 615 11313 99.6908  . . . . 0.171 . . . . . . . . . . . 0.196 
'X-RAY DIFFRACTION' 1.979 2.086 . . 571 10841 99.5725  . . . . 0.182 . . . . . . . . . . . 0.208 
'X-RAY DIFFRACTION' 2.086 2.212 . . 534 10201 99.5826  . . . . 0.166 . . . . . . . . . . . 0.191 
'X-RAY DIFFRACTION' 2.212 2.364 . . 503 9507  98.4364  . . . . 0.162 . . . . . . . . . . . 0.196 
'X-RAY DIFFRACTION' 2.364 2.553 . . 449 8708  96.3996  . . . . 0.153 . . . . . . . . . . . 0.182 
'X-RAY DIFFRACTION' 2.553 2.796 . . 409 8301  100.0000 . . . . 0.154 . . . . . . . . . . . 0.178 
'X-RAY DIFFRACTION' 2.796 3.125 . . 391 7501  99.7472  . . . . 0.153 . . . . . . . . . . . 0.178 
'X-RAY DIFFRACTION' 3.125 3.605 . . 364 6620  99.5865  . . . . 0.145 . . . . . . . . . . . 0.174 
'X-RAY DIFFRACTION' 3.605 4.409 . . 305 5550  98.9354  . . . . 0.126 . . . . . . . . . . . 0.160 
'X-RAY DIFFRACTION' 4.409 6.207 . . 240 4302  98.1205  . . . . 0.143 . . . . . . . . . . . 0.151 
'X-RAY DIFFRACTION' 6.207 46.17 . . 118 2516  99.9621  . . . . 0.206 . . . . . . . . . . . 0.215 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 A 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A TYR 32 . A ALA 556 . A TYR 24 A ALA 548 ? ? 
1 2 1 A TYR 32 . A ALA 556 . A TYR 24 A ALA 548 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9G88 
_struct.title                        'Carotenoid cleavage oxygenase from Moesziomyces aphidis bound to acetate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9G88 
_struct_keywords.text            'oxygenase, Moesziomyces aphidis, METAL BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'METAL BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    W3VHW6_MOEAP 
_struct_ref.pdbx_db_accession          W3VHW6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;APTATQEPVPVPVTSKAAPSHGYVHPTDILPSGWPTATDLSGGAQPRRFEGTIFDVMTRGTIPKELHGTFYRIMPDYAQP
PTYYKGGELNAPIDGDGTVAAFRFKDGKVDYRQRFVETDRFKVERRARKSMYGLYRNPYTHHPCVRQTVESTANTNVVMH
AGRFLAMKENGNAYEMDPHTLKTLGYNPFNLPSKTMTAHPKQCSVTGNLVGFGYEAKGLATKDVYYFEVDPSGKVVRDLW
LEAPWCAFIHDCALTPNYLVLMLWPFEANLERMKAGGHHWAYDYTKPITWITIPRGAKSKDEVKYWHWKNGMPIHTASGF
EDEQGRIIIDSSLVHGNAFPFFPPDSDEQKKKQEADGTPKAQFVRWTIDPRKDNNEQLPDPEVILDTPSEFPQIDNRFMG
VEYSSAFINVFVPDRSDGNKNVFQGLNGLAHYKRKEGTTEWYYAGDNCLIQEPVFSPRSKDAPEGDGFVLAIVDRLDLNR
SEVVVIDTRDFTKAVAAVQLPFAIRSGIHGQWIPGEVTPDFETKGLVDLPKEEHWAPLSQSPYDPDA
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9G88 A 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
2 1 9G88 B 10 ? 556 ? W3VHW6 2 ? 548 ? 2 548 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9G88 MET A 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 1  
1 9G88 TRP A 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 2  
1 9G88 SER A 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 3  
1 9G88 HIS A 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 4  
1 9G88 PRO A 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 5  
1 9G88 GLN A 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 6  
1 9G88 PHE A 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 7  
1 9G88 GLU A 8 ? UNP W3VHW6 ? ? 'expression tag'        0  8  
1 9G88 LYS A 9 ? UNP W3VHW6 ? ? 'expression tag'        1  9  
2 9G88 MET B 1 ? UNP W3VHW6 ? ? 'initiating methionine' -7 10 
2 9G88 TRP B 2 ? UNP W3VHW6 ? ? 'expression tag'        -6 11 
2 9G88 SER B 3 ? UNP W3VHW6 ? ? 'expression tag'        -5 12 
2 9G88 HIS B 4 ? UNP W3VHW6 ? ? 'expression tag'        -4 13 
2 9G88 PRO B 5 ? UNP W3VHW6 ? ? 'expression tag'        -3 14 
2 9G88 GLN B 6 ? UNP W3VHW6 ? ? 'expression tag'        -2 15 
2 9G88 PHE B 7 ? UNP W3VHW6 ? ? 'expression tag'        -1 16 
2 9G88 GLU B 8 ? UNP W3VHW6 ? ? 'expression tag'        0  17 
2 9G88 LYS B 9 ? UNP W3VHW6 ? ? 'expression tag'        1  18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,G 
2 1 B,E,F,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'light scattering' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 34  ? LEU A 39  ? HIS A 26  LEU A 31  5 ? 6  
HELX_P HELX_P2  AA2 TYR A 93  ? GLU A 97  ? TYR A 85  GLU A 89  5 ? 5  
HELX_P HELX_P3  AA3 THR A 127 ? ARG A 137 ? THR A 119 ARG A 129 1 ? 11 
HELX_P HELX_P4  AA4 ASN A 146 ? HIS A 150 ? ASN A 138 HIS A 142 5 ? 5  
HELX_P HELX_P5  AA5 HIS A 151 ? ARG A 155 ? HIS A 143 ARG A 147 5 ? 5  
HELX_P HELX_P6  AA6 ASN A 278 ? ALA A 284 ? ASN A 270 ALA A 276 1 ? 7  
HELX_P HELX_P7  AA7 SER A 308 ? VAL A 312 ? SER A 300 VAL A 304 5 ? 5  
HELX_P HELX_P8  AA8 SER A 355 ? GLY A 366 ? SER A 347 GLY A 358 1 ? 12 
HELX_P HELX_P9  AA9 ASN A 405 ? MET A 408 ? ASN A 397 MET A 400 5 ? 4  
HELX_P HELX_P10 AB1 ARG A 498 ? PHE A 500 ? ARG A 490 PHE A 492 5 ? 3  
HELX_P HELX_P11 AB2 GLU A 525 ? THR A 527 ? GLU A 517 THR A 519 5 ? 3  
HELX_P HELX_P12 AB3 PRO A 546 ? SER A 550 ? PRO A 538 SER A 542 5 ? 5  
HELX_P HELX_P13 AB4 HIS B 34  ? LEU B 39  ? HIS B 26  LEU B 31  5 ? 6  
HELX_P HELX_P14 AB5 TYR B 93  ? GLU B 97  ? TYR B 85  GLU B 89  5 ? 5  
HELX_P HELX_P15 AB6 THR B 127 ? ARG B 137 ? THR B 119 ARG B 129 1 ? 11 
HELX_P HELX_P16 AB7 ASN B 146 ? HIS B 150 ? ASN B 138 HIS B 142 5 ? 5  
HELX_P HELX_P17 AB8 HIS B 151 ? ARG B 155 ? HIS B 143 ARG B 147 5 ? 5  
HELX_P HELX_P18 AB9 ASN B 278 ? ALA B 284 ? ASN B 270 ALA B 276 1 ? 7  
HELX_P HELX_P19 AC1 SER B 308 ? VAL B 312 ? SER B 300 VAL B 304 5 ? 5  
HELX_P HELX_P20 AC2 SER B 355 ? GLY B 366 ? SER B 347 GLY B 358 1 ? 12 
HELX_P HELX_P21 AC3 ASN B 405 ? MET B 408 ? ASN B 397 MET B 400 5 ? 4  
HELX_P HELX_P22 AC4 ARG B 498 ? PHE B 500 ? ARG B 490 PHE B 492 5 ? 3  
HELX_P HELX_P23 AC5 GLU B 525 ? THR B 527 ? GLU B 517 THR B 519 5 ? 3  
HELX_P HELX_P24 AC6 PRO B 546 ? SER B 550 ? PRO B 538 SER B 542 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS 208 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 200 A FE2 602 1_555 ? ? ? ? ? ? ? 2.187 ? ? 
metalc2  metalc ? ? A HIS 259 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 251 A FE2 602 1_555 ? ? ? ? ? ? ? 2.165 ? ? 
metalc3  metalc ? ? A HIS 324 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 316 A FE2 602 1_555 ? ? ? ? ? ? ? 2.045 ? ? 
metalc4  metalc ? ? A HIS 518 NE2 ? ? ? 1_555 D FE2 . FE ? ? A HIS 510 A FE2 602 1_555 ? ? ? ? ? ? ? 2.160 ? ? 
metalc5  metalc ? ? C ACT .   O   ? ? ? 1_555 D FE2 . FE ? ? A ACT 601 A FE2 602 1_555 ? ? ? ? ? ? ? 2.004 ? ? 
metalc6  metalc ? ? D FE2 .   FE  ? ? ? 1_555 G HOH . O  ? ? A FE2 602 A HOH 900 1_555 ? ? ? ? ? ? ? 2.039 ? ? 
metalc7  metalc ? ? B HIS 208 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 200 B FE2 602 1_555 ? ? ? ? ? ? ? 2.177 ? ? 
metalc8  metalc ? ? B HIS 259 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 251 B FE2 602 1_555 ? ? ? ? ? ? ? 2.155 ? ? 
metalc9  metalc ? ? B HIS 324 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 316 B FE2 602 1_555 ? ? ? ? ? ? ? 2.071 ? ? 
metalc10 metalc ? ? B HIS 518 NE2 ? ? ? 1_555 F FE2 . FE ? ? B HIS 510 B FE2 602 1_555 ? ? ? ? ? ? ? 2.187 ? ? 
metalc11 metalc ? ? E ACT .   O   ? ? ? 1_555 F FE2 . FE ? ? B ACT 601 B FE2 602 1_555 ? ? ? ? ? ? ? 2.061 ? ? 
metalc12 metalc ? ? F FE2 .   FE  ? ? ? 1_555 H HOH . O  ? ? B FE2 602 B HOH 794 1_555 ? ? ? ? ? ? ? 2.050 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 259 ? A HIS 251 ? 1_555 87.7  ? 
2  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 95.2  ? 
3  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 94.0  ? 
4  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 85.7  ? 
5  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 172.6 ? 
6  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 90.0  ? 
7  NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? C ACT .   ? A ACT 601 ? 1_555 176.7 ? 
8  NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? C ACT .   ? A ACT 601 ? 1_555 90.5  ? 
9  NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? C ACT .   ? A ACT 601 ? 1_555 87.6  ? 
10 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? C ACT .   ? A ACT 601 ? 1_555 95.9  ? 
11 NE2 ? A HIS 208 ? A HIS 200 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 900 ? 1_555 90.4  ? 
12 NE2 ? A HIS 259 ? A HIS 251 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 900 ? 1_555 89.1  ? 
13 NE2 ? A HIS 324 ? A HIS 316 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 900 ? 1_555 173.7 ? 
14 NE2 ? A HIS 518 ? A HIS 510 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 900 ? 1_555 87.5  ? 
15 O   ? C ACT .   ? A ACT 601 ? 1_555 FE ? D FE2 . ? A FE2 602 ? 1_555 O   ? G HOH .   ? A HOH 900 ? 1_555 86.8  ? 
16 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 88.9  ? 
17 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 94.6  ? 
18 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 92.6  ? 
19 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 85.0  ? 
20 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 173.7 ? 
21 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 89.3  ? 
22 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? E ACT .   ? B ACT 601 ? 1_555 177.4 ? 
23 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? E ACT .   ? B ACT 601 ? 1_555 90.7  ? 
24 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? E ACT .   ? B ACT 601 ? 1_555 88.0  ? 
25 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? E ACT .   ? B ACT 601 ? 1_555 95.3  ? 
26 NE2 ? B HIS 208 ? B HIS 200 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 794 ? 1_555 91.9  ? 
27 NE2 ? B HIS 259 ? B HIS 251 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 794 ? 1_555 89.1  ? 
28 NE2 ? B HIS 324 ? B HIS 316 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 794 ? 1_555 173.3 ? 
29 NE2 ? B HIS 518 ? B HIS 510 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 794 ? 1_555 89.7  ? 
30 O   ? E ACT .   ? B ACT 601 ? 1_555 FE ? F FE2 . ? B FE2 602 ? 1_555 O   ? H HOH .   ? B HOH 794 ? 1_555 85.5  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 5  ? 
AA3 ? 5  ? 
AA4 ? 4  ? 
AA5 ? 4  ? 
AA6 ? 3  ? 
AA7 ? 4  ? 
AA8 ? 4  ? 
AA9 ? 4  ? 
AB1 ? 5  ? 
AB2 ? 5  ? 
AB3 ? 4  ? 
AB4 ? 4  ? 
AB5 ? 3  ? 
AB6 ? 4  ? 
AB7 ? 4  ? 
AB8 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA1 4 5  ? anti-parallel 
AA1 5 6  ? anti-parallel 
AA1 6 7  ? anti-parallel 
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA3 3 4  ? anti-parallel 
AA3 4 5  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA5 2 3  ? anti-parallel 
AA5 3 4  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA6 2 3  ? anti-parallel 
AA7 1 2  ? anti-parallel 
AA7 2 3  ? anti-parallel 
AA7 3 4  ? anti-parallel 
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? anti-parallel 
AA9 3 4  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB1 4 5  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB2 4 5  ? anti-parallel 
AB3 1 2  ? anti-parallel 
AB3 2 3  ? anti-parallel 
AB3 3 4  ? anti-parallel 
AB4 1 2  ? anti-parallel 
AB4 2 3  ? anti-parallel 
AB4 3 4  ? anti-parallel 
AB5 1 2  ? anti-parallel 
AB5 2 3  ? anti-parallel 
AB6 1 2  ? anti-parallel 
AB6 2 3  ? anti-parallel 
AB6 3 4  ? anti-parallel 
AB7 1 2  ? anti-parallel 
AB7 2 3  ? anti-parallel 
AB7 3 4  ? anti-parallel 
AB8 1 2  ? anti-parallel 
AB8 2 3  ? anti-parallel 
AB8 3 4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLY A 519 ? PRO A 523 ? GLY A 511 PRO A 515 
AA1 2  GLY A 77  ? PRO A 84  ? GLY A 69  PRO A 76  
AA1 3  GLY A 106 ? LYS A 114 ? GLY A 98  LYS A 106 
AA1 4  LYS A 117 ? PHE A 124 ? LYS A 109 PHE A 116 
AA1 5  GLU A 59  ? ILE A 62  ? GLU A 51  ILE A 54  
AA1 6  GLU B 59  ? ILE B 62  ? GLU B 51  ILE B 54  
AA1 7  LYS B 117 ? PHE B 124 ? LYS B 109 PHE B 116 
AA1 8  GLY B 106 ? LYS B 114 ? GLY B 98  LYS B 106 
AA1 9  GLY B 77  ? PRO B 84  ? GLY B 69  PRO B 76  
AA1 10 GLY B 519 ? PRO B 523 ? GLY B 511 PRO B 515 
AA2 1  MET A 66  ? GLY A 69  ? MET A 58  GLY A 61  
AA2 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA2 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA2 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA2 5  CYS A 457 ? ILE A 459 ? CYS A 449 ILE A 451 
AA3 1  MET A 66  ? GLY A 69  ? MET A 58  GLY A 61  
AA3 2  ALA A 503 ? GLN A 508 ? ALA A 495 GLN A 500 
AA3 3  ARG A 489 ? ASP A 496 ? ARG A 481 ASP A 488 
AA3 4  GLY A 476 ? ARG A 484 ? GLY A 468 ARG A 476 
AA3 5  VAL A 463 ? PRO A 466 ? VAL A 455 PRO A 458 
AA4 1  ASN A 165 ? HIS A 169 ? ASN A 157 HIS A 161 
AA4 2  ARG A 172 ? MET A 176 ? ARG A 164 MET A 168 
AA4 3  TYR A 183 ? MET A 185 ? TYR A 175 MET A 177 
AA4 4  THR A 192 ? TYR A 195 ? THR A 184 TYR A 187 
AA5 1  LYS A 210 ? GLN A 211 ? LYS A 202 GLN A 203 
AA5 2  LEU A 218 ? TYR A 223 ? LEU A 210 TYR A 215 
AA5 3  ASP A 232 ? VAL A 238 ? ASP A 224 VAL A 230 
AA5 4  VAL A 244 ? GLU A 251 ? VAL A 236 GLU A 243 
AA6 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA6 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA6 3  TRP A 289 ? TYR A 291 ? TRP A 281 TYR A 283 
AA7 1  ALA A 256 ? LEU A 263 ? ALA A 248 LEU A 255 
AA7 2  TYR A 267 ? ALA A 277 ? TYR A 259 ALA A 269 
AA7 3  THR A 298 ? PRO A 303 ? THR A 290 PRO A 295 
AA7 4  LYS A 313 ? HIS A 316 ? LYS A 305 HIS A 308 
AA8 1  THR A 325 ? GLU A 330 ? THR A 317 GLU A 322 
AA8 2  ILE A 336 ? VAL A 343 ? ILE A 328 VAL A 335 
AA8 3  ALA A 370 ? ILE A 377 ? ALA A 362 ILE A 369 
AA8 4  GLU A 391 ? LEU A 394 ? GLU A 383 LEU A 386 
AA9 1  SER A 398 ? ILE A 403 ? SER A 390 ILE A 395 
AA9 2  SER A 414 ? VAL A 419 ? SER A 406 VAL A 411 
AA9 3  GLY A 437 ? LYS A 442 ? GLY A 429 LYS A 434 
AA9 4  THR A 447 ? TYR A 452 ? THR A 439 TYR A 444 
AB1 1  MET B 66  ? GLY B 69  ? MET B 58  GLY B 61  
AB1 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB1 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB1 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB1 5  CYS B 457 ? ILE B 459 ? CYS B 449 ILE B 451 
AB2 1  MET B 66  ? GLY B 69  ? MET B 58  GLY B 61  
AB2 2  ALA B 503 ? GLN B 508 ? ALA B 495 GLN B 500 
AB2 3  ARG B 489 ? ASP B 496 ? ARG B 481 ASP B 488 
AB2 4  GLY B 476 ? ARG B 484 ? GLY B 468 ARG B 476 
AB2 5  VAL B 463 ? PRO B 466 ? VAL B 455 PRO B 458 
AB3 1  ASN B 165 ? HIS B 169 ? ASN B 157 HIS B 161 
AB3 2  ARG B 172 ? MET B 176 ? ARG B 164 MET B 168 
AB3 3  TYR B 183 ? MET B 185 ? TYR B 175 MET B 177 
AB3 4  THR B 192 ? TYR B 195 ? THR B 184 TYR B 187 
AB4 1  LYS B 210 ? GLN B 211 ? LYS B 202 GLN B 203 
AB4 2  LEU B 218 ? TYR B 223 ? LEU B 210 TYR B 215 
AB4 3  ASP B 232 ? VAL B 238 ? ASP B 224 VAL B 230 
AB4 4  VAL B 244 ? GLU B 251 ? VAL B 236 GLU B 243 
AB5 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB5 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB5 3  TRP B 289 ? TYR B 291 ? TRP B 281 TYR B 283 
AB6 1  ALA B 256 ? LEU B 263 ? ALA B 248 LEU B 255 
AB6 2  TYR B 267 ? ALA B 277 ? TYR B 259 ALA B 269 
AB6 3  THR B 298 ? PRO B 303 ? THR B 290 PRO B 295 
AB6 4  LYS B 313 ? HIS B 316 ? LYS B 305 HIS B 308 
AB7 1  THR B 325 ? GLU B 330 ? THR B 317 GLU B 322 
AB7 2  ILE B 336 ? VAL B 343 ? ILE B 328 VAL B 335 
AB7 3  ALA B 370 ? ILE B 377 ? ALA B 362 ILE B 369 
AB7 4  GLU B 391 ? LEU B 394 ? GLU B 383 LEU B 386 
AB8 1  SER B 398 ? ILE B 403 ? SER B 390 ILE B 395 
AB8 2  SER B 414 ? VAL B 419 ? SER B 406 VAL B 411 
AB8 3  GLY B 437 ? LYS B 442 ? GLY B 429 LYS B 434 
AB8 4  THR B 447 ? TYR B 452 ? THR B 439 TYR B 444 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O ILE A 522 ? O ILE A 514 N THR A 78  ? N THR A 70  
AA1 2 3  N ARG A 81  ? N ARG A 73  O ALA A 109 ? O ALA A 101 
AA1 3 4  N ALA A 110 ? N ALA A 102 O ARG A 121 ? O ARG A 113 
AA1 4 5  O GLN A 122 ? O GLN A 114 N GLY A 60  ? N GLY A 52  
AA1 5 6  N GLU A 59  ? N GLU A 51  O THR B 61  ? O THR B 53  
AA1 6 7  N GLY B 60  ? N GLY B 52  O GLN B 122 ? O GLN B 114 
AA1 7 8  O ARG B 121 ? O ARG B 113 N ALA B 110 ? N ALA B 102 
AA1 8 9  O ALA B 109 ? O ALA B 101 N ARG B 81  ? N ARG B 73  
AA1 9 10 N THR B 78  ? N THR B 70  O ILE B 522 ? O ILE B 514 
AA2 1 2  N MET A 66  ? N MET A 58  O GLN A 508 ? O GLN A 500 
AA2 2 3  O VAL A 507 ? O VAL A 499 N VAL A 492 ? N VAL A 484 
AA2 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA2 4 5  O ASP A 483 ? O ASP A 475 N LEU A 458 ? N LEU A 450 
AA3 1 2  N MET A 66  ? N MET A 58  O GLN A 508 ? O GLN A 500 
AA3 2 3  O VAL A 507 ? O VAL A 499 N VAL A 492 ? N VAL A 484 
AA3 3 4  O GLU A 491 ? O GLU A 483 N VAL A 482 ? N VAL A 474 
AA3 4 5  O PHE A 477 ? O PHE A 469 N SER A 465 ? N SER A 457 
AA4 1 2  N VAL A 167 ? N VAL A 159 O LEU A 174 ? O LEU A 166 
AA4 2 3  N ALA A 175 ? N ALA A 167 O TYR A 183 ? O TYR A 175 
AA4 3 4  N GLU A 184 ? N GLU A 176 O LEU A 193 ? O LEU A 185 
AA5 1 2  N LYS A 210 ? N LYS A 202 O VAL A 219 ? O VAL A 211 
AA5 2 3  N LEU A 218 ? N LEU A 210 O VAL A 238 ? O VAL A 230 
AA5 3 4  N TYR A 235 ? N TYR A 227 O LEU A 248 ? O LEU A 240 
AA6 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA6 2 3  N GLU A 276 ? N GLU A 268 O ALA A 290 ? O ALA A 282 
AA7 1 2  N ALA A 262 ? N ALA A 254 O VAL A 269 ? O VAL A 261 
AA7 2 3  N LEU A 272 ? N LEU A 264 O THR A 298 ? O THR A 290 
AA7 3 4  N TRP A 299 ? N TRP A 291 O TRP A 315 ? O TRP A 307 
AA8 1 2  N PHE A 329 ? N PHE A 321 O ILE A 337 ? O ILE A 329 
AA8 2 3  N ILE A 338 ? N ILE A 330 O TRP A 375 ? O TRP A 367 
AA8 3 4  N PHE A 372 ? N PHE A 364 O ILE A 393 ? O ILE A 385 
AA9 1 2  N GLN A 402 ? N GLN A 394 O PHE A 416 ? O PHE A 408 
AA9 2 3  N ILE A 417 ? N ILE A 409 O ALA A 439 ? O ALA A 431 
AA9 3 4  N LEU A 438 ? N LEU A 430 O TYR A 451 ? O TYR A 443 
AB1 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB1 2 3  O VAL B 504 ? O VAL B 496 N VAL B 494 ? N VAL B 486 
AB1 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB1 4 5  O ASP B 483 ? O ASP B 475 N LEU B 458 ? N LEU B 450 
AB2 1 2  N ARG B 68  ? N ARG B 60  O ALA B 506 ? O ALA B 498 
AB2 2 3  O VAL B 504 ? O VAL B 496 N VAL B 494 ? N VAL B 486 
AB2 3 4  O GLU B 491 ? O GLU B 483 N VAL B 482 ? N VAL B 474 
AB2 4 5  O PHE B 477 ? O PHE B 469 N SER B 465 ? N SER B 457 
AB3 1 2  N VAL B 167 ? N VAL B 159 O LEU B 174 ? O LEU B 166 
AB3 2 3  N ALA B 175 ? N ALA B 167 O TYR B 183 ? O TYR B 175 
AB3 3 4  N GLU B 184 ? N GLU B 176 O LEU B 193 ? O LEU B 185 
AB4 1 2  N LYS B 210 ? N LYS B 202 O VAL B 219 ? O VAL B 211 
AB4 2 3  N LEU B 218 ? N LEU B 210 O VAL B 238 ? O VAL B 230 
AB4 3 4  N TYR B 235 ? N TYR B 227 O LEU B 248 ? O LEU B 240 
AB5 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB5 2 3  N GLU B 276 ? N GLU B 268 O ALA B 290 ? O ALA B 282 
AB6 1 2  N ALA B 262 ? N ALA B 254 O VAL B 269 ? O VAL B 261 
AB6 2 3  N LEU B 272 ? N LEU B 264 O THR B 298 ? O THR B 290 
AB6 3 4  N THR B 301 ? N THR B 293 O LYS B 313 ? O LYS B 305 
AB7 1 2  N PHE B 329 ? N PHE B 321 O ILE B 337 ? O ILE B 329 
AB7 2 3  N ILE B 338 ? N ILE B 330 O TRP B 375 ? O TRP B 367 
AB7 3 4  N PHE B 372 ? N PHE B 364 O ILE B 393 ? O ILE B 385 
AB8 1 2  N GLN B 402 ? N GLN B 394 O PHE B 416 ? O PHE B 408 
AB8 2 3  N ILE B 417 ? N ILE B 409 O ALA B 439 ? O ALA B 431 
AB8 3 4  N LEU B 438 ? N LEU B 430 O TYR B 451 ? O TYR B 443 
# 
_pdbx_entry_details.entry_id                   9G88 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 CB  A THR 156 ? ? O A HOH 701  ? ? 1.39 
2 1 CG2 A THR 156 ? ? O A HOH 701  ? ? 1.89 
3 1 CG2 A THR 156 ? ? O A HOH 900  ? ? 2.02 
4 1 SG  B CYS 145 ? ? O B HOH 1209 ? ? 2.13 
5 1 N   B TYR 24  ? ? O B HOH 701  ? ? 2.13 
6 1 O   B HOH 821 ? ? O B HOH 1129 ? ? 2.17 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 49  ? ? CZ A ARG 49  ? ? NH1 A ARG 49  ? ? 123.79 120.30 3.49   0.50 N 
2  1 NE A ARG 49  ? ? CZ A ARG 49  ? ? NH2 A ARG 49  ? ? 116.62 120.30 -3.68  0.50 N 
3  1 CG A ARG 73  ? ? CD A ARG 73  ? ? NE  A ARG 73  ? ? 96.76  111.80 -15.04 2.10 N 
4  1 CG A MET 75  ? ? SD A MET 75  ? ? CE  A MET 75  ? ? 90.07  100.20 -10.13 1.60 N 
5  1 NE A ARG 121 ? ? CZ A ARG 121 ? ? NH2 A ARG 121 ? ? 116.49 120.30 -3.81  0.50 N 
6  1 NE A ARG 126 ? ? CZ A ARG 126 ? ? NH2 A ARG 126 ? ? 116.12 120.30 -4.18  0.50 N 
7  1 CD A ARG 164 ? ? NE A ARG 164 ? ? CZ  A ARG 164 ? ? 132.57 123.60 8.97   1.40 N 
8  1 NE A ARG 164 ? ? CZ A ARG 164 ? ? NH2 A ARG 164 ? ? 117.24 120.30 -3.06  0.50 N 
9  1 CB A LEU 220 ? ? CG A LEU 220 ? ? CD2 A LEU 220 ? ? 100.69 111.00 -10.31 1.70 N 
10 1 NE A ARG 238 ? ? CZ A ARG 238 ? ? NH2 A ARG 238 ? ? 116.66 120.30 -3.64  0.50 N 
11 1 NE B ARG 49  ? ? CZ B ARG 49  ? ? NH2 B ARG 49  ? ? 116.33 120.30 -3.97  0.50 N 
12 1 CG B ARG 73  ? ? CD B ARG 73  ? ? NE  B ARG 73  ? ? 125.56 111.80 13.76  2.10 N 
13 1 NE B ARG 115 ? ? CZ B ARG 115 ? ? NH2 B ARG 115 ? ? 116.26 120.30 -4.04  0.50 N 
14 1 NE B ARG 164 ? ? CZ B ARG 164 ? ? NH2 B ARG 164 ? ? 115.91 120.30 -4.39  0.50 N 
15 1 NE B ARG 238 ? ? CZ B ARG 238 ? ? NH1 B ARG 238 ? ? 123.32 120.30 3.02   0.50 N 
16 1 CB B GLU 517 ? ? CA B GLU 517 ? ? C   B GLU 517 ? ? 124.13 110.40 13.73  2.00 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 48  ? ? -111.34 -77.32  
2  1 ASP A 56  ? ? 62.24   65.09   
3  1 ASP A 77  ? ? -151.05 84.07   
4  1 TRP A 309 ? ? -117.01 -107.96 
5  1 ALA A 318 ? ? -72.01  -72.46  
6  1 PHE A 340 ? ? -117.77 71.33   
7  1 PHE A 343 ? ? -118.51 76.60   
8  1 ILE A 509 ? ? -107.28 -95.28  
9  1 ARG B 48  ? ? -114.18 -76.31  
10 1 ASP B 56  ? ? 61.51   64.12   
11 1 ASP B 77  ? ? -150.11 79.78   
12 1 GLN B 148 ? ? -99.10  32.36   
13 1 TRP B 309 ? ? -119.21 -107.34 
14 1 ALA B 318 ? ? -73.41  -71.52  
15 1 PHE B 340 ? ? -115.27 68.43   
16 1 PHE B 343 ? ? -118.76 76.50   
17 1 ILE B 509 ? ? -107.57 -93.59  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 164 ? ? 0.083 'SIDE CHAIN' 
2 1 ARG A 238 ? ? 0.082 'SIDE CHAIN' 
3 1 ARG A 416 ? ? 0.108 'SIDE CHAIN' 
4 1 ARG A 459 ? ? 0.076 'SIDE CHAIN' 
5 1 ARG B 238 ? ? 0.074 'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1396 ? 5.98 . 
2 1 O ? A HOH 1397 ? 6.36 . 
3 1 O ? A HOH 1398 ? 6.74 . 
4 1 O ? B HOH 1321 ? 6.35 . 
5 1 O ? B HOH 1322 ? 6.63 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -7 ? A MET 1  
2  1 Y 1 A TRP -6 ? A TRP 2  
3  1 Y 1 A SER -5 ? A SER 3  
4  1 Y 1 A HIS -4 ? A HIS 4  
5  1 Y 1 A PRO -3 ? A PRO 5  
6  1 Y 1 A GLN -2 ? A GLN 6  
7  1 Y 1 A PHE -1 ? A PHE 7  
8  1 Y 1 A GLU 0  ? A GLU 8  
9  1 Y 1 A LYS 1  ? A LYS 9  
10 1 Y 1 A ALA 2  ? A ALA 10 
11 1 Y 1 A PRO 3  ? A PRO 11 
12 1 Y 1 A THR 4  ? A THR 12 
13 1 Y 1 A ALA 5  ? A ALA 13 
14 1 Y 1 A THR 6  ? A THR 14 
15 1 Y 1 A GLN 7  ? A GLN 15 
16 1 Y 1 A GLU 8  ? A GLU 16 
17 1 Y 1 A PRO 9  ? A PRO 17 
18 1 Y 1 A VAL 10 ? A VAL 18 
19 1 Y 1 A PRO 11 ? A PRO 19 
20 1 Y 1 A VAL 12 ? A VAL 20 
21 1 Y 1 A PRO 13 ? A PRO 21 
22 1 Y 1 A VAL 14 ? A VAL 22 
23 1 Y 1 A THR 15 ? A THR 23 
24 1 Y 1 A SER 16 ? A SER 24 
25 1 Y 1 A LYS 17 ? A LYS 25 
26 1 Y 1 A ALA 18 ? A ALA 26 
27 1 Y 1 A ALA 19 ? A ALA 27 
28 1 Y 1 A PRO 20 ? A PRO 28 
29 1 Y 1 A SER 21 ? A SER 29 
30 1 Y 1 A HIS 22 ? A HIS 30 
31 1 Y 1 A GLY 23 ? A GLY 31 
32 1 Y 1 B MET -7 ? B MET 1  
33 1 Y 1 B TRP -6 ? B TRP 2  
34 1 Y 1 B SER -5 ? B SER 3  
35 1 Y 1 B HIS -4 ? B HIS 4  
36 1 Y 1 B PRO -3 ? B PRO 5  
37 1 Y 1 B GLN -2 ? B GLN 6  
38 1 Y 1 B PHE -1 ? B PHE 7  
39 1 Y 1 B GLU 0  ? B GLU 8  
40 1 Y 1 B LYS 1  ? B LYS 9  
41 1 Y 1 B ALA 2  ? B ALA 10 
42 1 Y 1 B PRO 3  ? B PRO 11 
43 1 Y 1 B THR 4  ? B THR 12 
44 1 Y 1 B ALA 5  ? B ALA 13 
45 1 Y 1 B THR 6  ? B THR 14 
46 1 Y 1 B GLN 7  ? B GLN 15 
47 1 Y 1 B GLU 8  ? B GLU 16 
48 1 Y 1 B PRO 9  ? B PRO 17 
49 1 Y 1 B VAL 10 ? B VAL 18 
50 1 Y 1 B PRO 11 ? B PRO 19 
51 1 Y 1 B VAL 12 ? B VAL 20 
52 1 Y 1 B PRO 13 ? B PRO 21 
53 1 Y 1 B VAL 14 ? B VAL 22 
54 1 Y 1 B THR 15 ? B THR 23 
55 1 Y 1 B SER 16 ? B SER 24 
56 1 Y 1 B LYS 17 ? B LYS 25 
57 1 Y 1 B ALA 18 ? B ALA 26 
58 1 Y 1 B ALA 19 ? B ALA 27 
59 1 Y 1 B PRO 20 ? B PRO 28 
60 1 Y 1 B SER 21 ? B SER 29 
61 1 Y 1 B HIS 22 ? B HIS 30 
62 1 Y 1 B GLY 23 ? B GLY 31 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ACT C    C  N N 1   
ACT O    O  N N 2   
ACT OXT  O  N N 3   
ACT CH3  C  N N 4   
ACT H1   H  N N 5   
ACT H2   H  N N 6   
ACT H3   H  N N 7   
ALA N    N  N N 8   
ALA CA   C  N S 9   
ALA C    C  N N 10  
ALA O    O  N N 11  
ALA CB   C  N N 12  
ALA OXT  O  N N 13  
ALA H    H  N N 14  
ALA H2   H  N N 15  
ALA HA   H  N N 16  
ALA HB1  H  N N 17  
ALA HB2  H  N N 18  
ALA HB3  H  N N 19  
ALA HXT  H  N N 20  
ARG N    N  N N 21  
ARG CA   C  N S 22  
ARG C    C  N N 23  
ARG O    O  N N 24  
ARG CB   C  N N 25  
ARG CG   C  N N 26  
ARG CD   C  N N 27  
ARG NE   N  N N 28  
ARG CZ   C  N N 29  
ARG NH1  N  N N 30  
ARG NH2  N  N N 31  
ARG OXT  O  N N 32  
ARG H    H  N N 33  
ARG H2   H  N N 34  
ARG HA   H  N N 35  
ARG HB2  H  N N 36  
ARG HB3  H  N N 37  
ARG HG2  H  N N 38  
ARG HG3  H  N N 39  
ARG HD2  H  N N 40  
ARG HD3  H  N N 41  
ARG HE   H  N N 42  
ARG HH11 H  N N 43  
ARG HH12 H  N N 44  
ARG HH21 H  N N 45  
ARG HH22 H  N N 46  
ARG HXT  H  N N 47  
ASN N    N  N N 48  
ASN CA   C  N S 49  
ASN C    C  N N 50  
ASN O    O  N N 51  
ASN CB   C  N N 52  
ASN CG   C  N N 53  
ASN OD1  O  N N 54  
ASN ND2  N  N N 55  
ASN OXT  O  N N 56  
ASN H    H  N N 57  
ASN H2   H  N N 58  
ASN HA   H  N N 59  
ASN HB2  H  N N 60  
ASN HB3  H  N N 61  
ASN HD21 H  N N 62  
ASN HD22 H  N N 63  
ASN HXT  H  N N 64  
ASP N    N  N N 65  
ASP CA   C  N S 66  
ASP C    C  N N 67  
ASP O    O  N N 68  
ASP CB   C  N N 69  
ASP CG   C  N N 70  
ASP OD1  O  N N 71  
ASP OD2  O  N N 72  
ASP OXT  O  N N 73  
ASP H    H  N N 74  
ASP H2   H  N N 75  
ASP HA   H  N N 76  
ASP HB2  H  N N 77  
ASP HB3  H  N N 78  
ASP HD2  H  N N 79  
ASP HXT  H  N N 80  
CYS N    N  N N 81  
CYS CA   C  N R 82  
CYS C    C  N N 83  
CYS O    O  N N 84  
CYS CB   C  N N 85  
CYS SG   S  N N 86  
CYS OXT  O  N N 87  
CYS H    H  N N 88  
CYS H2   H  N N 89  
CYS HA   H  N N 90  
CYS HB2  H  N N 91  
CYS HB3  H  N N 92  
CYS HG   H  N N 93  
CYS HXT  H  N N 94  
FE2 FE   FE N N 95  
GLN N    N  N N 96  
GLN CA   C  N S 97  
GLN C    C  N N 98  
GLN O    O  N N 99  
GLN CB   C  N N 100 
GLN CG   C  N N 101 
GLN CD   C  N N 102 
GLN OE1  O  N N 103 
GLN NE2  N  N N 104 
GLN OXT  O  N N 105 
GLN H    H  N N 106 
GLN H2   H  N N 107 
GLN HA   H  N N 108 
GLN HB2  H  N N 109 
GLN HB3  H  N N 110 
GLN HG2  H  N N 111 
GLN HG3  H  N N 112 
GLN HE21 H  N N 113 
GLN HE22 H  N N 114 
GLN HXT  H  N N 115 
GLU N    N  N N 116 
GLU CA   C  N S 117 
GLU C    C  N N 118 
GLU O    O  N N 119 
GLU CB   C  N N 120 
GLU CG   C  N N 121 
GLU CD   C  N N 122 
GLU OE1  O  N N 123 
GLU OE2  O  N N 124 
GLU OXT  O  N N 125 
GLU H    H  N N 126 
GLU H2   H  N N 127 
GLU HA   H  N N 128 
GLU HB2  H  N N 129 
GLU HB3  H  N N 130 
GLU HG2  H  N N 131 
GLU HG3  H  N N 132 
GLU HE2  H  N N 133 
GLU HXT  H  N N 134 
GLY N    N  N N 135 
GLY CA   C  N N 136 
GLY C    C  N N 137 
GLY O    O  N N 138 
GLY OXT  O  N N 139 
GLY H    H  N N 140 
GLY H2   H  N N 141 
GLY HA2  H  N N 142 
GLY HA3  H  N N 143 
GLY HXT  H  N N 144 
HIS N    N  N N 145 
HIS CA   C  N S 146 
HIS C    C  N N 147 
HIS O    O  N N 148 
HIS CB   C  N N 149 
HIS CG   C  Y N 150 
HIS ND1  N  Y N 151 
HIS CD2  C  Y N 152 
HIS CE1  C  Y N 153 
HIS NE2  N  Y N 154 
HIS OXT  O  N N 155 
HIS H    H  N N 156 
HIS H2   H  N N 157 
HIS HA   H  N N 158 
HIS HB2  H  N N 159 
HIS HB3  H  N N 160 
HIS HD1  H  N N 161 
HIS HD2  H  N N 162 
HIS HE1  H  N N 163 
HIS HE2  H  N N 164 
HIS HXT  H  N N 165 
HOH O    O  N N 166 
HOH H1   H  N N 167 
HOH H2   H  N N 168 
ILE N    N  N N 169 
ILE CA   C  N S 170 
ILE C    C  N N 171 
ILE O    O  N N 172 
ILE CB   C  N S 173 
ILE CG1  C  N N 174 
ILE CG2  C  N N 175 
ILE CD1  C  N N 176 
ILE OXT  O  N N 177 
ILE H    H  N N 178 
ILE H2   H  N N 179 
ILE HA   H  N N 180 
ILE HB   H  N N 181 
ILE HG12 H  N N 182 
ILE HG13 H  N N 183 
ILE HG21 H  N N 184 
ILE HG22 H  N N 185 
ILE HG23 H  N N 186 
ILE HD11 H  N N 187 
ILE HD12 H  N N 188 
ILE HD13 H  N N 189 
ILE HXT  H  N N 190 
LEU N    N  N N 191 
LEU CA   C  N S 192 
LEU C    C  N N 193 
LEU O    O  N N 194 
LEU CB   C  N N 195 
LEU CG   C  N N 196 
LEU CD1  C  N N 197 
LEU CD2  C  N N 198 
LEU OXT  O  N N 199 
LEU H    H  N N 200 
LEU H2   H  N N 201 
LEU HA   H  N N 202 
LEU HB2  H  N N 203 
LEU HB3  H  N N 204 
LEU HG   H  N N 205 
LEU HD11 H  N N 206 
LEU HD12 H  N N 207 
LEU HD13 H  N N 208 
LEU HD21 H  N N 209 
LEU HD22 H  N N 210 
LEU HD23 H  N N 211 
LEU HXT  H  N N 212 
LYS N    N  N N 213 
LYS CA   C  N S 214 
LYS C    C  N N 215 
LYS O    O  N N 216 
LYS CB   C  N N 217 
LYS CG   C  N N 218 
LYS CD   C  N N 219 
LYS CE   C  N N 220 
LYS NZ   N  N N 221 
LYS OXT  O  N N 222 
LYS H    H  N N 223 
LYS H2   H  N N 224 
LYS HA   H  N N 225 
LYS HB2  H  N N 226 
LYS HB3  H  N N 227 
LYS HG2  H  N N 228 
LYS HG3  H  N N 229 
LYS HD2  H  N N 230 
LYS HD3  H  N N 231 
LYS HE2  H  N N 232 
LYS HE3  H  N N 233 
LYS HZ1  H  N N 234 
LYS HZ2  H  N N 235 
LYS HZ3  H  N N 236 
LYS HXT  H  N N 237 
MET N    N  N N 238 
MET CA   C  N S 239 
MET C    C  N N 240 
MET O    O  N N 241 
MET CB   C  N N 242 
MET CG   C  N N 243 
MET SD   S  N N 244 
MET CE   C  N N 245 
MET OXT  O  N N 246 
MET H    H  N N 247 
MET H2   H  N N 248 
MET HA   H  N N 249 
MET HB2  H  N N 250 
MET HB3  H  N N 251 
MET HG2  H  N N 252 
MET HG3  H  N N 253 
MET HE1  H  N N 254 
MET HE2  H  N N 255 
MET HE3  H  N N 256 
MET HXT  H  N N 257 
PHE N    N  N N 258 
PHE CA   C  N S 259 
PHE C    C  N N 260 
PHE O    O  N N 261 
PHE CB   C  N N 262 
PHE CG   C  Y N 263 
PHE CD1  C  Y N 264 
PHE CD2  C  Y N 265 
PHE CE1  C  Y N 266 
PHE CE2  C  Y N 267 
PHE CZ   C  Y N 268 
PHE OXT  O  N N 269 
PHE H    H  N N 270 
PHE H2   H  N N 271 
PHE HA   H  N N 272 
PHE HB2  H  N N 273 
PHE HB3  H  N N 274 
PHE HD1  H  N N 275 
PHE HD2  H  N N 276 
PHE HE1  H  N N 277 
PHE HE2  H  N N 278 
PHE HZ   H  N N 279 
PHE HXT  H  N N 280 
PRO N    N  N N 281 
PRO CA   C  N S 282 
PRO C    C  N N 283 
PRO O    O  N N 284 
PRO CB   C  N N 285 
PRO CG   C  N N 286 
PRO CD   C  N N 287 
PRO OXT  O  N N 288 
PRO H    H  N N 289 
PRO HA   H  N N 290 
PRO HB2  H  N N 291 
PRO HB3  H  N N 292 
PRO HG2  H  N N 293 
PRO HG3  H  N N 294 
PRO HD2  H  N N 295 
PRO HD3  H  N N 296 
PRO HXT  H  N N 297 
SER N    N  N N 298 
SER CA   C  N S 299 
SER C    C  N N 300 
SER O    O  N N 301 
SER CB   C  N N 302 
SER OG   O  N N 303 
SER OXT  O  N N 304 
SER H    H  N N 305 
SER H2   H  N N 306 
SER HA   H  N N 307 
SER HB2  H  N N 308 
SER HB3  H  N N 309 
SER HG   H  N N 310 
SER HXT  H  N N 311 
THR N    N  N N 312 
THR CA   C  N S 313 
THR C    C  N N 314 
THR O    O  N N 315 
THR CB   C  N R 316 
THR OG1  O  N N 317 
THR CG2  C  N N 318 
THR OXT  O  N N 319 
THR H    H  N N 320 
THR H2   H  N N 321 
THR HA   H  N N 322 
THR HB   H  N N 323 
THR HG1  H  N N 324 
THR HG21 H  N N 325 
THR HG22 H  N N 326 
THR HG23 H  N N 327 
THR HXT  H  N N 328 
TRP N    N  N N 329 
TRP CA   C  N S 330 
TRP C    C  N N 331 
TRP O    O  N N 332 
TRP CB   C  N N 333 
TRP CG   C  Y N 334 
TRP CD1  C  Y N 335 
TRP CD2  C  Y N 336 
TRP NE1  N  Y N 337 
TRP CE2  C  Y N 338 
TRP CE3  C  Y N 339 
TRP CZ2  C  Y N 340 
TRP CZ3  C  Y N 341 
TRP CH2  C  Y N 342 
TRP OXT  O  N N 343 
TRP H    H  N N 344 
TRP H2   H  N N 345 
TRP HA   H  N N 346 
TRP HB2  H  N N 347 
TRP HB3  H  N N 348 
TRP HD1  H  N N 349 
TRP HE1  H  N N 350 
TRP HE3  H  N N 351 
TRP HZ2  H  N N 352 
TRP HZ3  H  N N 353 
TRP HH2  H  N N 354 
TRP HXT  H  N N 355 
TYR N    N  N N 356 
TYR CA   C  N S 357 
TYR C    C  N N 358 
TYR O    O  N N 359 
TYR CB   C  N N 360 
TYR CG   C  Y N 361 
TYR CD1  C  Y N 362 
TYR CD2  C  Y N 363 
TYR CE1  C  Y N 364 
TYR CE2  C  Y N 365 
TYR CZ   C  Y N 366 
TYR OH   O  N N 367 
TYR OXT  O  N N 368 
TYR H    H  N N 369 
TYR H2   H  N N 370 
TYR HA   H  N N 371 
TYR HB2  H  N N 372 
TYR HB3  H  N N 373 
TYR HD1  H  N N 374 
TYR HD2  H  N N 375 
TYR HE1  H  N N 376 
TYR HE2  H  N N 377 
TYR HH   H  N N 378 
TYR HXT  H  N N 379 
VAL N    N  N N 380 
VAL CA   C  N S 381 
VAL C    C  N N 382 
VAL O    O  N N 383 
VAL CB   C  N N 384 
VAL CG1  C  N N 385 
VAL CG2  C  N N 386 
VAL OXT  O  N N 387 
VAL H    H  N N 388 
VAL H2   H  N N 389 
VAL HA   H  N N 390 
VAL HB   H  N N 391 
VAL HG11 H  N N 392 
VAL HG12 H  N N 393 
VAL HG13 H  N N 394 
VAL HG21 H  N N 395 
VAL HG22 H  N N 396 
VAL HG23 H  N N 397 
VAL HXT  H  N N 398 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ACT C   O    doub N N 1   
ACT C   OXT  sing N N 2   
ACT C   CH3  sing N N 3   
ACT CH3 H1   sing N N 4   
ACT CH3 H2   sing N N 5   
ACT CH3 H3   sing N N 6   
ALA N   CA   sing N N 7   
ALA N   H    sing N N 8   
ALA N   H2   sing N N 9   
ALA CA  C    sing N N 10  
ALA CA  CB   sing N N 11  
ALA CA  HA   sing N N 12  
ALA C   O    doub N N 13  
ALA C   OXT  sing N N 14  
ALA CB  HB1  sing N N 15  
ALA CB  HB2  sing N N 16  
ALA CB  HB3  sing N N 17  
ALA OXT HXT  sing N N 18  
ARG N   CA   sing N N 19  
ARG N   H    sing N N 20  
ARG N   H2   sing N N 21  
ARG CA  C    sing N N 22  
ARG CA  CB   sing N N 23  
ARG CA  HA   sing N N 24  
ARG C   O    doub N N 25  
ARG C   OXT  sing N N 26  
ARG CB  CG   sing N N 27  
ARG CB  HB2  sing N N 28  
ARG CB  HB3  sing N N 29  
ARG CG  CD   sing N N 30  
ARG CG  HG2  sing N N 31  
ARG CG  HG3  sing N N 32  
ARG CD  NE   sing N N 33  
ARG CD  HD2  sing N N 34  
ARG CD  HD3  sing N N 35  
ARG NE  CZ   sing N N 36  
ARG NE  HE   sing N N 37  
ARG CZ  NH1  sing N N 38  
ARG CZ  NH2  doub N N 39  
ARG NH1 HH11 sing N N 40  
ARG NH1 HH12 sing N N 41  
ARG NH2 HH21 sing N N 42  
ARG NH2 HH22 sing N N 43  
ARG OXT HXT  sing N N 44  
ASN N   CA   sing N N 45  
ASN N   H    sing N N 46  
ASN N   H2   sing N N 47  
ASN CA  C    sing N N 48  
ASN CA  CB   sing N N 49  
ASN CA  HA   sing N N 50  
ASN C   O    doub N N 51  
ASN C   OXT  sing N N 52  
ASN CB  CG   sing N N 53  
ASN CB  HB2  sing N N 54  
ASN CB  HB3  sing N N 55  
ASN CG  OD1  doub N N 56  
ASN CG  ND2  sing N N 57  
ASN ND2 HD21 sing N N 58  
ASN ND2 HD22 sing N N 59  
ASN OXT HXT  sing N N 60  
ASP N   CA   sing N N 61  
ASP N   H    sing N N 62  
ASP N   H2   sing N N 63  
ASP CA  C    sing N N 64  
ASP CA  CB   sing N N 65  
ASP CA  HA   sing N N 66  
ASP C   O    doub N N 67  
ASP C   OXT  sing N N 68  
ASP CB  CG   sing N N 69  
ASP CB  HB2  sing N N 70  
ASP CB  HB3  sing N N 71  
ASP CG  OD1  doub N N 72  
ASP CG  OD2  sing N N 73  
ASP OD2 HD2  sing N N 74  
ASP OXT HXT  sing N N 75  
CYS N   CA   sing N N 76  
CYS N   H    sing N N 77  
CYS N   H2   sing N N 78  
CYS CA  C    sing N N 79  
CYS CA  CB   sing N N 80  
CYS CA  HA   sing N N 81  
CYS C   O    doub N N 82  
CYS C   OXT  sing N N 83  
CYS CB  SG   sing N N 84  
CYS CB  HB2  sing N N 85  
CYS CB  HB3  sing N N 86  
CYS SG  HG   sing N N 87  
CYS OXT HXT  sing N N 88  
GLN N   CA   sing N N 89  
GLN N   H    sing N N 90  
GLN N   H2   sing N N 91  
GLN CA  C    sing N N 92  
GLN CA  CB   sing N N 93  
GLN CA  HA   sing N N 94  
GLN C   O    doub N N 95  
GLN C   OXT  sing N N 96  
GLN CB  CG   sing N N 97  
GLN CB  HB2  sing N N 98  
GLN CB  HB3  sing N N 99  
GLN CG  CD   sing N N 100 
GLN CG  HG2  sing N N 101 
GLN CG  HG3  sing N N 102 
GLN CD  OE1  doub N N 103 
GLN CD  NE2  sing N N 104 
GLN NE2 HE21 sing N N 105 
GLN NE2 HE22 sing N N 106 
GLN OXT HXT  sing N N 107 
GLU N   CA   sing N N 108 
GLU N   H    sing N N 109 
GLU N   H2   sing N N 110 
GLU CA  C    sing N N 111 
GLU CA  CB   sing N N 112 
GLU CA  HA   sing N N 113 
GLU C   O    doub N N 114 
GLU C   OXT  sing N N 115 
GLU CB  CG   sing N N 116 
GLU CB  HB2  sing N N 117 
GLU CB  HB3  sing N N 118 
GLU CG  CD   sing N N 119 
GLU CG  HG2  sing N N 120 
GLU CG  HG3  sing N N 121 
GLU CD  OE1  doub N N 122 
GLU CD  OE2  sing N N 123 
GLU OE2 HE2  sing N N 124 
GLU OXT HXT  sing N N 125 
GLY N   CA   sing N N 126 
GLY N   H    sing N N 127 
GLY N   H2   sing N N 128 
GLY CA  C    sing N N 129 
GLY CA  HA2  sing N N 130 
GLY CA  HA3  sing N N 131 
GLY C   O    doub N N 132 
GLY C   OXT  sing N N 133 
GLY OXT HXT  sing N N 134 
HIS N   CA   sing N N 135 
HIS N   H    sing N N 136 
HIS N   H2   sing N N 137 
HIS CA  C    sing N N 138 
HIS CA  CB   sing N N 139 
HIS CA  HA   sing N N 140 
HIS C   O    doub N N 141 
HIS C   OXT  sing N N 142 
HIS CB  CG   sing N N 143 
HIS CB  HB2  sing N N 144 
HIS CB  HB3  sing N N 145 
HIS CG  ND1  sing Y N 146 
HIS CG  CD2  doub Y N 147 
HIS ND1 CE1  doub Y N 148 
HIS ND1 HD1  sing N N 149 
HIS CD2 NE2  sing Y N 150 
HIS CD2 HD2  sing N N 151 
HIS CE1 NE2  sing Y N 152 
HIS CE1 HE1  sing N N 153 
HIS NE2 HE2  sing N N 154 
HIS OXT HXT  sing N N 155 
HOH O   H1   sing N N 156 
HOH O   H2   sing N N 157 
ILE N   CA   sing N N 158 
ILE N   H    sing N N 159 
ILE N   H2   sing N N 160 
ILE CA  C    sing N N 161 
ILE CA  CB   sing N N 162 
ILE CA  HA   sing N N 163 
ILE C   O    doub N N 164 
ILE C   OXT  sing N N 165 
ILE CB  CG1  sing N N 166 
ILE CB  CG2  sing N N 167 
ILE CB  HB   sing N N 168 
ILE CG1 CD1  sing N N 169 
ILE CG1 HG12 sing N N 170 
ILE CG1 HG13 sing N N 171 
ILE CG2 HG21 sing N N 172 
ILE CG2 HG22 sing N N 173 
ILE CG2 HG23 sing N N 174 
ILE CD1 HD11 sing N N 175 
ILE CD1 HD12 sing N N 176 
ILE CD1 HD13 sing N N 177 
ILE OXT HXT  sing N N 178 
LEU N   CA   sing N N 179 
LEU N   H    sing N N 180 
LEU N   H2   sing N N 181 
LEU CA  C    sing N N 182 
LEU CA  CB   sing N N 183 
LEU CA  HA   sing N N 184 
LEU C   O    doub N N 185 
LEU C   OXT  sing N N 186 
LEU CB  CG   sing N N 187 
LEU CB  HB2  sing N N 188 
LEU CB  HB3  sing N N 189 
LEU CG  CD1  sing N N 190 
LEU CG  CD2  sing N N 191 
LEU CG  HG   sing N N 192 
LEU CD1 HD11 sing N N 193 
LEU CD1 HD12 sing N N 194 
LEU CD1 HD13 sing N N 195 
LEU CD2 HD21 sing N N 196 
LEU CD2 HD22 sing N N 197 
LEU CD2 HD23 sing N N 198 
LEU OXT HXT  sing N N 199 
LYS N   CA   sing N N 200 
LYS N   H    sing N N 201 
LYS N   H2   sing N N 202 
LYS CA  C    sing N N 203 
LYS CA  CB   sing N N 204 
LYS CA  HA   sing N N 205 
LYS C   O    doub N N 206 
LYS C   OXT  sing N N 207 
LYS CB  CG   sing N N 208 
LYS CB  HB2  sing N N 209 
LYS CB  HB3  sing N N 210 
LYS CG  CD   sing N N 211 
LYS CG  HG2  sing N N 212 
LYS CG  HG3  sing N N 213 
LYS CD  CE   sing N N 214 
LYS CD  HD2  sing N N 215 
LYS CD  HD3  sing N N 216 
LYS CE  NZ   sing N N 217 
LYS CE  HE2  sing N N 218 
LYS CE  HE3  sing N N 219 
LYS NZ  HZ1  sing N N 220 
LYS NZ  HZ2  sing N N 221 
LYS NZ  HZ3  sing N N 222 
LYS OXT HXT  sing N N 223 
MET N   CA   sing N N 224 
MET N   H    sing N N 225 
MET N   H2   sing N N 226 
MET CA  C    sing N N 227 
MET CA  CB   sing N N 228 
MET CA  HA   sing N N 229 
MET C   O    doub N N 230 
MET C   OXT  sing N N 231 
MET CB  CG   sing N N 232 
MET CB  HB2  sing N N 233 
MET CB  HB3  sing N N 234 
MET CG  SD   sing N N 235 
MET CG  HG2  sing N N 236 
MET CG  HG3  sing N N 237 
MET SD  CE   sing N N 238 
MET CE  HE1  sing N N 239 
MET CE  HE2  sing N N 240 
MET CE  HE3  sing N N 241 
MET OXT HXT  sing N N 242 
PHE N   CA   sing N N 243 
PHE N   H    sing N N 244 
PHE N   H2   sing N N 245 
PHE CA  C    sing N N 246 
PHE CA  CB   sing N N 247 
PHE CA  HA   sing N N 248 
PHE C   O    doub N N 249 
PHE C   OXT  sing N N 250 
PHE CB  CG   sing N N 251 
PHE CB  HB2  sing N N 252 
PHE CB  HB3  sing N N 253 
PHE CG  CD1  doub Y N 254 
PHE CG  CD2  sing Y N 255 
PHE CD1 CE1  sing Y N 256 
PHE CD1 HD1  sing N N 257 
PHE CD2 CE2  doub Y N 258 
PHE CD2 HD2  sing N N 259 
PHE CE1 CZ   doub Y N 260 
PHE CE1 HE1  sing N N 261 
PHE CE2 CZ   sing Y N 262 
PHE CE2 HE2  sing N N 263 
PHE CZ  HZ   sing N N 264 
PHE OXT HXT  sing N N 265 
PRO N   CA   sing N N 266 
PRO N   CD   sing N N 267 
PRO N   H    sing N N 268 
PRO CA  C    sing N N 269 
PRO CA  CB   sing N N 270 
PRO CA  HA   sing N N 271 
PRO C   O    doub N N 272 
PRO C   OXT  sing N N 273 
PRO CB  CG   sing N N 274 
PRO CB  HB2  sing N N 275 
PRO CB  HB3  sing N N 276 
PRO CG  CD   sing N N 277 
PRO CG  HG2  sing N N 278 
PRO CG  HG3  sing N N 279 
PRO CD  HD2  sing N N 280 
PRO CD  HD3  sing N N 281 
PRO OXT HXT  sing N N 282 
SER N   CA   sing N N 283 
SER N   H    sing N N 284 
SER N   H2   sing N N 285 
SER CA  C    sing N N 286 
SER CA  CB   sing N N 287 
SER CA  HA   sing N N 288 
SER C   O    doub N N 289 
SER C   OXT  sing N N 290 
SER CB  OG   sing N N 291 
SER CB  HB2  sing N N 292 
SER CB  HB3  sing N N 293 
SER OG  HG   sing N N 294 
SER OXT HXT  sing N N 295 
THR N   CA   sing N N 296 
THR N   H    sing N N 297 
THR N   H2   sing N N 298 
THR CA  C    sing N N 299 
THR CA  CB   sing N N 300 
THR CA  HA   sing N N 301 
THR C   O    doub N N 302 
THR C   OXT  sing N N 303 
THR CB  OG1  sing N N 304 
THR CB  CG2  sing N N 305 
THR CB  HB   sing N N 306 
THR OG1 HG1  sing N N 307 
THR CG2 HG21 sing N N 308 
THR CG2 HG22 sing N N 309 
THR CG2 HG23 sing N N 310 
THR OXT HXT  sing N N 311 
TRP N   CA   sing N N 312 
TRP N   H    sing N N 313 
TRP N   H2   sing N N 314 
TRP CA  C    sing N N 315 
TRP CA  CB   sing N N 316 
TRP CA  HA   sing N N 317 
TRP C   O    doub N N 318 
TRP C   OXT  sing N N 319 
TRP CB  CG   sing N N 320 
TRP CB  HB2  sing N N 321 
TRP CB  HB3  sing N N 322 
TRP CG  CD1  doub Y N 323 
TRP CG  CD2  sing Y N 324 
TRP CD1 NE1  sing Y N 325 
TRP CD1 HD1  sing N N 326 
TRP CD2 CE2  doub Y N 327 
TRP CD2 CE3  sing Y N 328 
TRP NE1 CE2  sing Y N 329 
TRP NE1 HE1  sing N N 330 
TRP CE2 CZ2  sing Y N 331 
TRP CE3 CZ3  doub Y N 332 
TRP CE3 HE3  sing N N 333 
TRP CZ2 CH2  doub Y N 334 
TRP CZ2 HZ2  sing N N 335 
TRP CZ3 CH2  sing Y N 336 
TRP CZ3 HZ3  sing N N 337 
TRP CH2 HH2  sing N N 338 
TRP OXT HXT  sing N N 339 
TYR N   CA   sing N N 340 
TYR N   H    sing N N 341 
TYR N   H2   sing N N 342 
TYR CA  C    sing N N 343 
TYR CA  CB   sing N N 344 
TYR CA  HA   sing N N 345 
TYR C   O    doub N N 346 
TYR C   OXT  sing N N 347 
TYR CB  CG   sing N N 348 
TYR CB  HB2  sing N N 349 
TYR CB  HB3  sing N N 350 
TYR CG  CD1  doub Y N 351 
TYR CG  CD2  sing Y N 352 
TYR CD1 CE1  sing Y N 353 
TYR CD1 HD1  sing N N 354 
TYR CD2 CE2  doub Y N 355 
TYR CD2 HD2  sing N N 356 
TYR CE1 CZ   doub Y N 357 
TYR CE1 HE1  sing N N 358 
TYR CE2 CZ   sing Y N 359 
TYR CE2 HE2  sing N N 360 
TYR CZ  OH   sing N N 361 
TYR OH  HH   sing N N 362 
TYR OXT HXT  sing N N 363 
VAL N   CA   sing N N 364 
VAL N   H    sing N N 365 
VAL N   H2   sing N N 366 
VAL CA  C    sing N N 367 
VAL CA  CB   sing N N 368 
VAL CA  HA   sing N N 369 
VAL C   O    doub N N 370 
VAL C   OXT  sing N N 371 
VAL CB  CG1  sing N N 372 
VAL CB  CG2  sing N N 373 
VAL CB  HB   sing N N 374 
VAL CG1 HG11 sing N N 375 
VAL CG1 HG12 sing N N 376 
VAL CG1 HG13 sing N N 377 
VAL CG2 HG21 sing N N 378 
VAL CG2 HG22 sing N N 379 
VAL CG2 HG23 sing N N 380 
VAL OXT HXT  sing N N 381 
# 
_pdbx_audit_support.funding_organization   'Austrian Science Fund' 
_pdbx_audit_support.country                Austria 
_pdbx_audit_support.grant_number           P33687 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9G88 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013859 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.002528 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011634 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.010829 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
FE 26 26 11.7738 4.7611  7.3600 0.3072  3.5235 15.3535 2.3054 76.8805 1.2402   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0650   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . TYR A 1 32  ? 6.887   -32.411 20.594  1   49.636 ? 24   TYR A N   1 
ATOM   2    C  CA  . TYR A 1 32  ? 6.359   -31.419 19.612  1   52.481 ? 24   TYR A CA  1 
ATOM   3    C  C   . TYR A 1 32  ? 6.958   -30.041 19.888  1   51.509 ? 24   TYR A C   1 
ATOM   4    O  O   . TYR A 1 32  ? 6.887   -29.542 21.011  1   51.147 ? 24   TYR A O   1 
ATOM   5    C  CB  . TYR A 1 32  ? 4.831   -31.287 19.645  1   55.861 ? 24   TYR A CB  1 
ATOM   6    C  CG  . TYR A 1 32  ? 4.243   -30.312 18.626  1   54.965 ? 24   TYR A CG  1 
ATOM   7    C  CD1 . TYR A 1 32  ? 4.088   -30.695 17.288  1   49.969 ? 24   TYR A CD1 1 
ATOM   8    C  CD2 . TYR A 1 32  ? 3.838   -29.021 18.997  1   44.178 ? 24   TYR A CD2 1 
ATOM   9    C  CE1 . TYR A 1 32  ? 3.558   -29.822 16.346  1   47.761 ? 24   TYR A CE1 1 
ATOM   10   C  CE2 . TYR A 1 32  ? 3.319   -28.135 18.06   1   46.065 ? 24   TYR A CE2 1 
ATOM   11   C  CZ  . TYR A 1 32  ? 3.182   -28.543 16.742  1   43.02  ? 24   TYR A CZ  1 
ATOM   12   O  OH  . TYR A 1 32  ? 2.641   -27.716 15.816  1   38.061 ? 24   TYR A OH  1 
ATOM   13   N  N   . VAL A 1 33  ? 7.504   -29.429 18.828  1   44.949 ? 25   VAL A N   1 
ATOM   14   C  CA  . VAL A 1 33  ? 7.906   -28.025 18.814  1   47.219 ? 25   VAL A CA  1 
ATOM   15   C  C   . VAL A 1 33  ? 7.058   -27.35  17.734  1   43.983 ? 25   VAL A C   1 
ATOM   16   O  O   . VAL A 1 33  ? 6.911   -27.905 16.645  1   38.015 ? 25   VAL A O   1 
ATOM   17   C  CB  . VAL A 1 33  ? 9.416   -27.752 18.601  1   47.865 ? 25   VAL A CB  1 
ATOM   18   C  CG1 . VAL A 1 33  ? 9.764   -26.28  18.805  1   49.872 ? 25   VAL A CG1 1 
ATOM   19   C  CG2 . VAL A 1 33  ? 10.313  -28.62  19.493  1   50.947 ? 25   VAL A CG2 1 
ATOM   20   N  N   . HIS A 1 34  ? 6.476   -26.178 18.043  1   34.583 ? 26   HIS A N   1 
ATOM   21   C  CA  . HIS A 1 34  ? 5.73    -25.433 17.036  1   29.855 ? 26   HIS A CA  1 
ATOM   22   C  C   . HIS A 1 34  ? 6.738   -24.875 16.028  1   28.97  ? 26   HIS A C   1 
ATOM   23   O  O   . HIS A 1 34  ? 7.704   -24.23  16.44   1   30.594 ? 26   HIS A O   1 
ATOM   24   C  CB  . HIS A 1 34  ? 4.915   -24.303 17.689  1   29.515 ? 26   HIS A CB  1 
ATOM   25   C  CG  . HIS A 1 34  ? 3.866   -23.764 16.768  1   25.565 ? 26   HIS A CG  1 
ATOM   26   N  ND1 . HIS A 1 34  ? 4.165   -23.07  15.607  1   28.389 ? 26   HIS A ND1 1 
ATOM   27   C  CD2 . HIS A 1 34  ? 2.537   -23.934 16.811  1   26.012 ? 26   HIS A CD2 1 
ATOM   28   C  CE1 . HIS A 1 34  ? 3.021   -22.792 14.978  1   25.709 ? 26   HIS A CE1 1 
ATOM   29   N  NE2 . HIS A 1 34  ? 2.023   -23.278 15.703  1   25.774 ? 26   HIS A NE2 1 
ATOM   30   N  N   . PRO A 1 35  ? 6.591   -25.09  14.693  1   27.047 ? 27   PRO A N   1 
ATOM   31   C  CA  . PRO A 1 35  ? 7.588   -24.608 13.74   1   25.777 ? 27   PRO A CA  1 
ATOM   32   C  C   . PRO A 1 35  ? 7.896   -23.108 13.804  1   28.591 ? 27   PRO A C   1 
ATOM   33   O  O   . PRO A 1 35  ? 9.035   -22.704 13.56   1   26.9   ? 27   PRO A O   1 
ATOM   34   C  CB  . PRO A 1 35  ? 7.022   -24.986 12.353  1   29.893 ? 27   PRO A CB  1 
ATOM   35   C  CG  . PRO A 1 35  ? 6.015   -26.054 12.649  1   31.174 ? 27   PRO A CG  1 
ATOM   36   C  CD  . PRO A 1 35  ? 5.487   -25.843 14.061  1   27.676 ? 27   PRO A CD  1 
ATOM   37   N  N   . THR A 1 36  ? 6.893   -22.284 14.157  1   28.417 ? 28   THR A N   1 
ATOM   38   C  CA  . THR A 1 36  ? 7.152   -20.837 14.212  1   27.004 ? 28   THR A CA  1 
ATOM   39   C  C   . THR A 1 36  ? 8.001   -20.461 15.442  1   25.746 ? 28   THR A C   1 
ATOM   40   O  O   . THR A 1 36  ? 8.588   -19.388 15.476  1   24.189 ? 28   THR A O   1 
ATOM   41   C  CB  . THR A 1 36  ? 5.892   -19.976 14.113  1   28.029 ? 28   THR A CB  1 
ATOM   42   O  OG1 . THR A 1 36  ? 5.15    -20.269 15.278  1   25.291 ? 28   THR A OG1 1 
ATOM   43   C  CG2 . THR A 1 36  ? 5.036   -20.321 12.909  1   27.675 ? 28   THR A CG2 1 
ATOM   44   N  N   . ASP A 1 37  ? 8.089   -21.37  16.417  1   26.89  ? 29   ASP A N   1 
ATOM   45   C  CA  . ASP A 1 37  ? 8.816   -21.095 17.661  1   26.453 ? 29   ASP A CA  1 
ATOM   46   C  C   . ASP A 1 37  ? 10.323  -21.206 17.479  1   27.89  ? 29   ASP A C   1 
ATOM   47   O  O   . ASP A 1 37  ? 11.054  -20.769 18.368  1   33.936 ? 29   ASP A O   1 
ATOM   48   C  CB  . ASP A 1 37  ? 8.314   -21.902 18.846  1   25.822 ? 29   ASP A CB  1 
ATOM   49   C  CG  . ASP A 1 37  ? 6.938   -21.491 19.342  1   27.734 ? 29   ASP A CG  1 
ATOM   50   O  OD1 . ASP A 1 37  ? 6.439   -20.43  18.878  1   28.673 ? 29   ASP A OD1 1 
ATOM   51   O  OD2 . ASP A 1 37  ? 6.358   -22.27  20.118  1   27.713 ? 29   ASP A OD2 1 
ATOM   52   N  N   . ILE A 1 38  ? 10.77   -21.833 16.389  1   29.571 ? 30   ILE A N   1 
ATOM   53   C  CA  . ILE A 1 38  ? 12.198  -21.89  16.092  1   36.244 ? 30   ILE A CA  1 
ATOM   54   C  C   . ILE A 1 38  ? 12.656  -20.727 15.202  1   34.468 ? 30   ILE A C   1 
ATOM   55   O  O   . ILE A 1 38  ? 13.853  -20.592 14.955  1   34.233 ? 30   ILE A O   1 
ATOM   56   C  CB  . ILE A 1 38  ? 12.661  -23.282 15.603  1   38.777 ? 30   ILE A CB  1 
ATOM   57   C  CG1 . ILE A 1 38  ? 12.169  -23.609 14.184  1   38.747 ? 30   ILE A CG1 1 
ATOM   58   C  CG2 . ILE A 1 38  ? 12.283  -24.348 16.638  1   46.833 ? 30   ILE A CG2 1 
ATOM   59   C  CD1 . ILE A 1 38  ? 12.947  -24.707 13.468  1   44.072 ? 30   ILE A CD1 1 
ATOM   60   N  N   . LEU A 1 39  ? 11.729  -19.861 14.745  1   28.578 ? 31   LEU A N   1 
ATOM   61   C  CA  . LEU A 1 39  ? 12.126  -18.67  14      1   28.376 ? 31   LEU A CA  1 
ATOM   62   C  C   . LEU A 1 39  ? 12.85   -17.735 14.97   1   29.249 ? 31   LEU A C   1 
ATOM   63   O  O   . LEU A 1 39  ? 12.405  -17.631 16.112  1   29.765 ? 31   LEU A O   1 
ATOM   64   C  CB  . LEU A 1 39  ? 10.911  -17.977 13.372  1   27.596 ? 31   LEU A CB  1 
ATOM   65   C  CG  . LEU A 1 39  ? 10.095  -18.784 12.353  1   26.294 ? 31   LEU A CG  1 
ATOM   66   C  CD1 . LEU A 1 39  ? 8.785   -18.092 12.005  1   26.869 ? 31   LEU A CD1 1 
ATOM   67   C  CD2 . LEU A 1 39  ? 10.865  -19.058 11.049  1   31.355 ? 31   LEU A CD2 1 
ATOM   68   N  N   . PRO A 1 40  ? 13.987  -17.082 14.605  1   30.26  ? 32   PRO A N   1 
ATOM   69   C  CA  . PRO A 1 40  ? 14.776  -16.314 15.567  1   31.295 ? 32   PRO A CA  1 
ATOM   70   C  C   . PRO A 1 40  ? 14.115  -15.043 16.088  1   31.119 ? 32   PRO A C   1 
ATOM   71   O  O   . PRO A 1 40  ? 13.487  -14.281 15.353  1   27.599 ? 32   PRO A O   1 
ATOM   72   C  CB  . PRO A 1 40  ? 16.077  -15.974 14.802  1   28.723 ? 32   PRO A CB  1 
ATOM   73   C  CG  . PRO A 1 40  ? 15.654  -15.948 13.339  1   32.252 ? 32   PRO A CG  1 
ATOM   74   C  CD  . PRO A 1 40  ? 14.596  -17.056 13.256  1   30.786 ? 32   PRO A CD  1 
ATOM   75   N  N   . SER A 1 41  ? 14.358  -14.805 17.374  1   34.532 ? 33   SER A N   1 
ATOM   76   C  CA  . SER A 1 41  ? 14.058  -13.559 18.043  1   29.319 ? 33   SER A CA  1 
ATOM   77   C  C   . SER A 1 41  ? 15.366  -12.779 18.232  1   31.501 ? 33   SER A C   1 
ATOM   78   O  O   . SER A 1 41  ? 16.433  -13.357 18.501  1   40.101 ? 33   SER A O   1 
ATOM   79   C  CB  . SER A 1 41  ? 13.41   -13.899 19.348  1   33.282 ? 33   SER A CB  1 
ATOM   80   O  OG  . SER A 1 41  ? 13.264  -12.745 20.166  1   27.343 ? 33   SER A OG  1 
ATOM   81   N  N   . GLY A 1 42  ? 15.261  -11.467 18.048  1   26.985 ? 34   GLY A N   1 
ATOM   82   C  CA  . GLY A 1 42  ? 16.291  -10.49  18.357  1   24.185 ? 34   GLY A CA  1 
ATOM   83   C  C   . GLY A 1 42  ? 16.305  -10.052 19.826  1   25.578 ? 34   GLY A C   1 
ATOM   84   O  O   . GLY A 1 42  ? 17.104  -9.168  20.174  1   27.621 ? 34   GLY A O   1 
ATOM   85   N  N   . TRP A 1 43  ? 15.428  -10.625 20.667  1   21.144 ? 35   TRP A N   1 
ATOM   86   C  CA  . TRP A 1 43  ? 15.404  -10.18  22.053  1   21.23  ? 35   TRP A CA  1 
ATOM   87   C  C   . TRP A 1 43  ? 16.425  -10.942 22.89   1   21.183 ? 35   TRP A C   1 
ATOM   88   O  O   . TRP A 1 43  ? 16.476  -12.187 22.858  1   22.853 ? 35   TRP A O   1 
ATOM   89   C  CB  . TRP A 1 43  ? 14.015  -10.364 22.669  1   19.918 ? 35   TRP A CB  1 
ATOM   90   C  CG  . TRP A 1 43  ? 13.149  -9.142  22.505  1   18.537 ? 35   TRP A CG  1 
ATOM   91   C  CD1 . TRP A 1 43  ? 12.471  -8.751  21.381  1   19.577 ? 35   TRP A CD1 1 
ATOM   92   C  CD2 . TRP A 1 43  ? 12.896  -8.14   23.504  1   16.057 ? 35   TRP A CD2 1 
ATOM   93   N  NE1 . TRP A 1 43  ? 11.81   -7.573  21.604  1   19.836 ? 35   TRP A NE1 1 
ATOM   94   C  CE2 . TRP A 1 43  ? 12.056  -7.175  22.888  1   17.262 ? 35   TRP A CE2 1 
ATOM   95   C  CE3 . TRP A 1 43  ? 13.3    -7.988  24.832  1   16.962 ? 35   TRP A CE3 1 
ATOM   96   C  CZ2 . TRP A 1 43  ? 11.604  -6.059  23.589  1   15.331 ? 35   TRP A CZ2 1 
ATOM   97   C  CZ3 . TRP A 1 43  ? 12.841  -6.887  25.543  1   15.756 ? 35   TRP A CZ3 1 
ATOM   98   C  CH2 . TRP A 1 43  ? 12.048  -5.917  24.889  1   15.963 ? 35   TRP A CH2 1 
ATOM   99   N  N   . PRO A 1 44  ? 17.2    -10.234 23.737  1   19.668 ? 36   PRO A N   1 
ATOM   100  C  CA  . PRO A 1 44  ? 17.96   -10.899 24.801  1   20.772 ? 36   PRO A CA  1 
ATOM   101  C  C   . PRO A 1 44  ? 16.989  -11.261 25.925  1   24.774 ? 36   PRO A C   1 
ATOM   102  O  O   . PRO A 1 44  ? 15.817  -10.862 25.905  1   23.843 ? 36   PRO A O   1 
ATOM   103  C  CB  . PRO A 1 44  ? 18.992  -9.852  25.197  1   22.783 ? 36   PRO A CB  1 
ATOM   104  C  CG  . PRO A 1 44  ? 18.245  -8.563  24.996  1   24.495 ? 36   PRO A CG  1 
ATOM   105  C  CD  . PRO A 1 44  ? 17.337  -8.766  23.769  1   20.846 ? 36   PRO A CD  1 
ATOM   106  N  N   . THR A 1 45  ? 17.48   -12.055 26.876  1   21.067 ? 37   THR A N   1 
ATOM   107  C  CA  . THR A 1 45  ? 16.683  -12.455 28.018  1   19.83  ? 37   THR A CA  1 
ATOM   108  C  C   . THR A 1 45  ? 16.592  -11.269 28.973  1   19.402 ? 37   THR A C   1 
ATOM   109  O  O   . THR A 1 45  ? 17.617  -10.878 29.538  1   25.31  ? 37   THR A O   1 
ATOM   110  C  CB  . THR A 1 45  ? 17.357  -13.625 28.723  1   21.246 ? 37   THR A CB  1 
ATOM   111  O  OG1 . THR A 1 45  ? 17.37   -14.656 27.745  1   25.824 ? 37   THR A OG1 1 
ATOM   112  C  CG2 . THR A 1 45  ? 16.436  -14.14  29.815  1   22.338 ? 37   THR A CG2 1 
ATOM   113  N  N   . ALA A 1 46  ? 15.388  -10.695 29.119  1   20.598 ? 38   ALA A N   1 
ATOM   114  C  CA  . ALA A 1 46  ? 15.178  -9.487  29.923  1   19.539 ? 38   ALA A CA  1 
ATOM   115  C  C   . ALA A 1 46  ? 14.296  -9.888  31.108  1   17.63  ? 38   ALA A C   1 
ATOM   116  O  O   . ALA A 1 46  ? 13.063  -9.945  30.989  1   17.27  ? 38   ALA A O   1 
ATOM   117  C  CB  . ALA A 1 46  ? 14.474  -8.436  29.043  1   22.43  ? 38   ALA A CB  1 
ATOM   118  N  N   . THR A 1 47  ? 14.931  -10.287 32.225  1   16.745 ? 39   THR A N   1 
ATOM   119  C  CA  . THR A 1 47  ? 14.174  -10.744 33.398  1   16.615 ? 39   THR A CA  1 
ATOM   120  C  C   . THR A 1 47  ? 13.651  -9.551  34.214  1   15.672 ? 39   THR A C   1 
ATOM   121  O  O   . THR A 1 47  ? 14.164  -8.432  34.139  1   16.852 ? 39   THR A O   1 
ATOM   122  C  CB  . THR A 1 47  ? 15.004  -11.626 34.336  1   17.266 ? 39   THR A CB  1 
ATOM   123  O  OG1 . THR A 1 47  ? 16.018  -10.841 34.962  1   18.336 ? 39   THR A OG1 1 
ATOM   124  C  CG2 . THR A 1 47  ? 15.631  -12.81  33.599  1   16.98  ? 39   THR A CG2 1 
ATOM   125  N  N   . ASP A 1 48  ? 12.635  -9.864  35.025  1   15.119 ? 40   ASP A N   1 
ATOM   126  C  CA  . ASP A 1 48  ? 12.219  -8.992  36.124  1   15.297 ? 40   ASP A CA  1 
ATOM   127  C  C   . ASP A 1 48  ? 12.649  -9.705  37.413  1   16.195 ? 40   ASP A C   1 
ATOM   128  O  O   . ASP A 1 48  ? 13.261  -10.773 37.366  1   16.042 ? 40   ASP A O   1 
ATOM   129  C  CB  . ASP A 1 48  ? 10.726  -8.675  36.017  1   14.139 ? 40   ASP A CB  1 
ATOM   130  C  CG  . ASP A 1 48  ? 9.79    -9.866  36.115  1   17.102 ? 40   ASP A CG  1 
ATOM   131  O  OD1 . ASP A 1 48  ? 10.025  -10.734 36.978  1   16.315 ? 40   ASP A OD1 1 
ATOM   132  O  OD2 . ASP A 1 48  ? 8.814   -9.905  35.343  1   17.221 ? 40   ASP A OD2 1 
ATOM   133  N  N   . LEU A 1 49  ? 12.369  -9.112  38.58   1   16.01  ? 41   LEU A N   1 
ATOM   134  C  CA  . LEU A 1 49  ? 12.912  -9.666  39.814  1   15.523 ? 41   LEU A CA  1 
ATOM   135  C  C   . LEU A 1 49  ? 12.377  -11.068 40.099  1   16.478 ? 41   LEU A C   1 
ATOM   136  O  O   . LEU A 1 49  ? 13.058  -11.837 40.79   1   17.202 ? 41   LEU A O   1 
ATOM   137  C  CB  . LEU A 1 49  ? 12.584  -8.771  41.002  1   16.795 ? 41   LEU A CB  1 
ATOM   138  C  CG  . LEU A 1 49  ? 13.513  -7.569  41.148  1   18.322 ? 41   LEU A CG  1 
ATOM   139  C  CD1 . LEU A 1 49  ? 12.881  -6.692  42.235  1   20.352 ? 41   LEU A CD1 1 
ATOM   140  C  CD2 . LEU A 1 49  ? 14.965  -7.958  41.52   1   17.447 ? 41   LEU A CD2 1 
ATOM   141  N  N   . SER A 1 50  ? 11.182  -11.409 39.603  1   16.351 ? 42   SER A N   1 
ATOM   142  C  CA  . SER A 1 50  ? 10.649  -12.755 39.808  1   18.444 ? 42   SER A CA  1 
ATOM   143  C  C   . SER A 1 50  ? 11.452  -13.815 39.041  1   15.981 ? 42   SER A C   1 
ATOM   144  O  O   . SER A 1 50  ? 11.298  -15.014 39.33   1   18.468 ? 42   SER A O   1 
ATOM   145  C  CB  . SER A 1 50  ? 9.156   -12.845 39.371  1   17.89  ? 42   SER A CB  1 
ATOM   146  O  OG  . SER A 1 50  ? 9.062   -12.876 37.964  1   18.494 ? 42   SER A OG  1 
ATOM   147  N  N   . GLY A 1 51  ? 12.246  -13.394 38.062  1   16.183 ? 43   GLY A N   1 
ATOM   148  C  CA  . GLY A 1 51  ? 12.933  -14.286 37.132  1   17.923 ? 43   GLY A CA  1 
ATOM   149  C  C   . GLY A 1 51  ? 12.195  -14.466 35.801  1   19.141 ? 43   GLY A C   1 
ATOM   150  O  O   . GLY A 1 51  ? 12.785  -14.98  34.838  1   19.224 ? 43   GLY A O   1 
ATOM   151  N  N   . GLY A 1 52  ? 10.935  -14.007 35.756  1   18.726 ? 44   GLY A N   1 
ATOM   152  C  CA  . GLY A 1 52  ? 10.148  -14.099 34.531  1   17.395 ? 44   GLY A CA  1 
ATOM   153  C  C   . GLY A 1 52  ? 10.782  -13.247 33.434  1   18.266 ? 44   GLY A C   1 
ATOM   154  O  O   . GLY A 1 52  ? 11.364  -12.205 33.715  1   17.816 ? 44   GLY A O   1 
ATOM   155  N  N   . ALA A 1 53  ? 10.676  -13.687 32.166  1   17.651 ? 45   ALA A N   1 
ATOM   156  C  CA  . ALA A 1 53  ? 11.415  -12.987 31.125  1   19.478 ? 45   ALA A CA  1 
ATOM   157  C  C   . ALA A 1 53  ? 10.531  -12.682 29.915  1   19.133 ? 45   ALA A C   1 
ATOM   158  O  O   . ALA A 1 53  ? 11.064  -12.518 28.811  1   22.894 ? 45   ALA A O   1 
ATOM   159  C  CB  . ALA A 1 53  ? 12.619  -13.788 30.713  1   21.719 ? 45   ALA A CB  1 
ATOM   160  N  N   . GLN A 1 54  ? 9.205   -12.618 30.12   1   17.586 ? 46   GLN A N   1 
ATOM   161  C  CA  . GLN A 1 54  ? 8.367   -12.313 28.964  1   15.285 ? 46   GLN A CA  1 
ATOM   162  C  C   . GLN A 1 54  ? 8.153   -10.798 28.861  1   14.6   ? 46   GLN A C   1 
ATOM   163  O  O   . GLN A 1 54  ? 7.499   -10.23  29.724  1   15.173 ? 46   GLN A O   1 
ATOM   164  C  CB  . GLN A 1 54  ? 7.004   -13.025 29.041  1   18.23  ? 46   GLN A CB  1 
ATOM   165  C  CG  . GLN A 1 54  ? 5.988   -12.718 27.926  1   25.963 ? 46   GLN A CG  1 
ATOM   166  C  CD  . GLN A 1 54  ? 6.463   -12.884 26.491  1   32.339 ? 46   GLN A CD  1 
ATOM   167  O  OE1 . GLN A 1 54  ? 7.113   -13.879 26.128  1   30.735 ? 46   GLN A OE1 1 
ATOM   168  N  NE2 . GLN A 1 54  ? 6.211   -11.856 25.676  1   23.716 ? 46   GLN A NE2 1 
ATOM   169  N  N   . PRO A 1 55  ? 8.603   -10.107 27.799  1   14.854 ? 47   PRO A N   1 
ATOM   170  C  CA  . PRO A 1 55  ? 8.268   -8.689  27.63   1   14.253 ? 47   PRO A CA  1 
ATOM   171  C  C   . PRO A 1 55  ? 6.77    -8.49   27.43   1   14.456 ? 47   PRO A C   1 
ATOM   172  O  O   . PRO A 1 55  ? 6.117   -9.312  26.752  1   15.31  ? 47   PRO A O   1 
ATOM   173  C  CB  . PRO A 1 55  ? 9.048   -8.267  26.39   1   15.891 ? 47   PRO A CB  1 
ATOM   174  C  CG  . PRO A 1 55  ? 10.186  -9.32   26.289  1   15.836 ? 47   PRO A CG  1 
ATOM   175  C  CD  . PRO A 1 55  ? 9.485   -10.607 26.708  1   15.39  ? 47   PRO A CD  1 
ATOM   176  N  N   . ARG A 1 56  ? 6.224   -7.444  28.065  1   12.417 ? 48   ARG A N   1 
ATOM   177  C  CA  . ARG A 1 56  ? 4.782   -7.172  27.942  1   13.846 ? 48   ARG A CA  1 
ATOM   178  C  C   . ARG A 1 56  ? 4.627   -5.888  27.141  1   14.554 ? 48   ARG A C   1 
ATOM   179  O  O   . ARG A 1 56  ? 4.285   -5.947  25.952  1   14.447 ? 48   ARG A O   1 
ATOM   180  C  CB  . ARG A 1 56  ? 4.166   -7.155  29.347  1   14.042 ? 48   ARG A CB  1 
ATOM   181  C  CG  . ARG A 1 56  ? 4.293   -8.418  30.187  1   14.698 ? 48   ARG A CG  1 
ATOM   182  C  CD  . ARG A 1 56  ? 3.673   -9.646  29.538  1   15.47  ? 48   ARG A CD  1 
ATOM   183  N  NE  . ARG A 1 56  ? 3.898   -10.773 30.459  1   16.275 ? 48   ARG A NE  1 
ATOM   184  C  CZ  . ARG A 1 56  ? 3.452   -12.003 30.177  1   20.131 ? 48   ARG A CZ  1 
ATOM   185  N  NH1 . ARG A 1 56  ? 2.68    -12.258 29.117  1   18.856 ? 48   ARG A NH1 1 
ATOM   186  N  NH2 . ARG A 1 56  ? 3.77    -12.993 31.003  1   22.524 ? 48   ARG A NH2 1 
ATOM   187  N  N   . ARG A 1 57  ? 4.857   -4.728  27.78   1   13.597 ? 49   ARG A N   1 
ATOM   188  C  CA  . ARG A 1 57  ? 5.092   -3.465  27.061  1   14.38  ? 49   ARG A CA  1 
ATOM   189  C  C   . ARG A 1 57  ? 3.815   -2.826  26.497  1   15.063 ? 49   ARG A C   1 
ATOM   190  O  O   . ARG A 1 57  ? 3.914   -1.889  25.713  1   18.388 ? 49   ARG A O   1 
ATOM   191  C  CB  . ARG A 1 57  ? 6.147   -3.535  25.951  1   14.189 ? 49   ARG A CB  1 
ATOM   192  C  CG  . ARG A 1 57  ? 7.443   -4.267  26.369  1   14.555 ? 49   ARG A CG  1 
ATOM   193  C  CD  . ARG A 1 57  ? 8.434   -4.443  25.241  1   16.607 ? 49   ARG A CD  1 
ATOM   194  N  NE  . ARG A 1 57  ? 7.852   -5.194  24.131  1   17.966 ? 49   ARG A NE  1 
ATOM   195  C  CZ  . ARG A 1 57  ? 7.935   -4.853  22.841  1   15.72  ? 49   ARG A CZ  1 
ATOM   196  N  NH1 . ARG A 1 57  ? 8.611   -3.801  22.398  1   16.545 ? 49   ARG A NH1 1 
ATOM   197  N  NH2 . ARG A 1 57  ? 7.295   -5.608  21.996  1   17.006 ? 49   ARG A NH2 1 
ATOM   198  N  N   . PHE A 1 58  ? 2.657   -3.279  26.89   1   16.967 ? 50   PHE A N   1 
ATOM   199  C  CA  . PHE A 1 58  ? 1.498   -2.6    26.362  1   16.397 ? 50   PHE A CA  1 
ATOM   200  C  C   . PHE A 1 58  ? 1.195   -1.369  27.203  1   13.161 ? 50   PHE A C   1 
ATOM   201  O  O   . PHE A 1 58  ? 1.462   -1.245  28.406  1   15.553 ? 50   PHE A O   1 
ATOM   202  C  CB  . PHE A 1 58  ? 0.359   -3.58   26.125  1   20.163 ? 50   PHE A CB  1 
ATOM   203  C  CG  . PHE A 1 58  ? 0.187   -4.488  27.324  1   16.664 ? 50   PHE A CG  1 
ATOM   204  C  CD1 . PHE A 1 58  ? -0.42   -4.078  28.511  1   19.915 ? 50   PHE A CD1 1 
ATOM   205  C  CD2 . PHE A 1 58  ? 0.717   -5.795  27.261  1   19.499 ? 50   PHE A CD2 1 
ATOM   206  C  CE1 . PHE A 1 58  ? -0.555  -5.032  29.561  1   21.56  ? 50   PHE A CE1 1 
ATOM   207  C  CE2 . PHE A 1 58  ? 0.597   -6.732  28.314  1   21.023 ? 50   PHE A CE2 1 
ATOM   208  C  CZ  . PHE A 1 58  ? -0.048  -6.355  29.453  1   18.209 ? 50   PHE A CZ  1 
ATOM   209  N  N   . GLU A 1 59  ? 0.506   -0.462  26.515  1   12.669 ? 51   GLU A N   1 
ATOM   210  C  CA  . GLU A 1 59  ? 0.099   0.817   27.093  1   11.994 ? 51   GLU A CA  1 
ATOM   211  C  C   . GLU A 1 59  ? -1.36   1.03    26.749  1   12.191 ? 51   GLU A C   1 
ATOM   212  O  O   . GLU A 1 59  ? -1.729  1.1     25.554  1   13.172 ? 51   GLU A O   1 
ATOM   213  C  CB  . GLU A 1 59  ? 0.91    1.975   26.483  1   11.534 ? 51   GLU A CB  1 
ATOM   214  C  CG  . GLU A 1 59  ? 2.425   1.788   26.702  1   13.118 ? 51   GLU A CG  1 
ATOM   215  C  CD  . GLU A 1 59  ? 3.147   3.085   26.382  1   12.854 ? 51   GLU A CD  1 
ATOM   216  O  OE1 . GLU A 1 59  ? 3.332   3.343   25.16   1   13.668 ? 51   GLU A OE1 1 
ATOM   217  O  OE2 . GLU A 1 59  ? 3.466   3.864   27.312  1   12.1   ? 51   GLU A OE2 1 
ATOM   218  N  N   . GLY A 1 60  ? -2.21   1.11    27.789  1   12.452 ? 52   GLY A N   1 
ATOM   219  C  CA  . GLY A 1 60  ? -3.618  1.309   27.486  1   12.951 ? 52   GLY A CA  1 
ATOM   220  C  C   . GLY A 1 60  ? -4.477  0.96    28.692  1   12.178 ? 52   GLY A C   1 
ATOM   221  O  O   . GLY A 1 60  ? -3.976  0.958   29.819  1   13.431 ? 52   GLY A O   1 
ATOM   222  N  N   . THR A 1 61  ? -5.746  0.705   28.428  1   12.751 ? 53   THR A N   1 
ATOM   223  C  CA  . THR A 1 61  ? -6.745  0.622   29.5    1   12.893 ? 53   THR A CA  1 
ATOM   224  C  C   . THR A 1 61  ? -7.659  -0.584  29.326  1   11.764 ? 53   THR A C   1 
ATOM   225  O  O   . THR A 1 61  ? -7.849  -1.118  28.226  1   12.511 ? 53   THR A O   1 
ATOM   226  C  CB  . THR A 1 61  ? -7.601  1.88    29.547  1   12.011 ? 53   THR A CB  1 
ATOM   227  O  OG1 . THR A 1 61  ? -8.275  2.057   28.283  1   14.206 ? 53   THR A OG1 1 
ATOM   228  C  CG2 . THR A 1 61  ? -6.794  3.14    29.834  1   13.943 ? 53   THR A CG2 1 
ATOM   229  N  N   . ILE A 1 62  ? -8.282  -0.955  30.456  1   12.065 ? 54   ILE A N   1 
ATOM   230  C  CA  . ILE A 1 62  ? -9.517  -1.752  30.446  1   12.393 ? 54   ILE A CA  1 
ATOM   231  C  C   . ILE A 1 62  ? -10.477 -1.058  31.393  1   12.273 ? 54   ILE A C   1 
ATOM   232  O  O   . ILE A 1 62  ? -10.175 -0.795  32.553  1   12.377 ? 54   ILE A O   1 
ATOM   233  C  CB  . ILE A 1 62  ? -9.272  -3.181  30.965  1   13.586 ? 54   ILE A CB  1 
ATOM   234  C  CG1 . ILE A 1 62  ? -8.278  -3.882  30.049  1   15.151 ? 54   ILE A CG1 1 
ATOM   235  C  CG2 . ILE A 1 62  ? -10.6   -3.934  31.111  1   17.19  ? 54   ILE A CG2 1 
ATOM   236  C  CD1 . ILE A 1 62  ? -7.672  -5.095  30.72   1   20.129 ? 54   ILE A CD1 1 
ATOM   237  N  N   . PHE A 1 63  ? -11.647 -0.708  30.833  1   13.12  ? 55   PHE A N   1 
ATOM   238  C  CA  . PHE A 1 63  ? -12.719 -0.112  31.596  1   12.465 ? 55   PHE A CA  1 
ATOM   239  C  C   . PHE A 1 63  ? -13.592 -1.207  32.229  1   13.537 ? 55   PHE A C   1 
ATOM   240  O  O   . PHE A 1 63  ? -13.977 -2.138  31.515  1   13.167 ? 55   PHE A O   1 
ATOM   241  C  CB  . PHE A 1 63  ? -13.554 0.761   30.653  1   13.189 ? 55   PHE A CB  1 
ATOM   242  C  CG  . PHE A 1 63  ? -14.669 1.478   31.368  1   14.345 ? 55   PHE A CG  1 
ATOM   243  C  CD1 . PHE A 1 63  ? -14.453 2.739   31.974  1   14.4   ? 55   PHE A CD1 1 
ATOM   244  C  CD2 . PHE A 1 63  ? -15.963 0.957   31.316  1   14.278 ? 55   PHE A CD2 1 
ATOM   245  C  CE1 . PHE A 1 63  ? -15.489 3.428   32.573  1   15.947 ? 55   PHE A CE1 1 
ATOM   246  C  CE2 . PHE A 1 63  ? -17.005 1.653   31.939  1   14.805 ? 55   PHE A CE2 1 
ATOM   247  C  CZ  . PHE A 1 63  ? -16.792 2.868   32.567  1   15.187 ? 55   PHE A CZ  1 
ATOM   248  N  N   . ASP A 1 64  ? -13.796 -1.146  33.549  1   13.228 ? 56   ASP A N   1 
ATOM   249  C  CA  . ASP A 1 64  ? -14.628 -2.098  34.288  1   13.23  ? 56   ASP A CA  1 
ATOM   250  C  C   . ASP A 1 64  ? -14.027 -3.506  34.166  1   12.93  ? 56   ASP A C   1 
ATOM   251  O  O   . ASP A 1 64  ? -14.571 -4.439  33.544  1   12.63  ? 56   ASP A O   1 
ATOM   252  C  CB  . ASP A 1 64  ? -16.081 -2.026  33.804  1   12.408 ? 56   ASP A CB  1 
ATOM   253  C  CG  . ASP A 1 64  ? -17.095 -2.43   34.851  1   17.227 ? 56   ASP A CG  1 
ATOM   254  O  OD1 . ASP A 1 64  ? -16.781 -2.371  36.044  1   17.313 ? 56   ASP A OD1 1 
ATOM   255  O  OD2 . ASP A 1 64  ? -18.23  -2.705  34.462  1   19.585 ? 56   ASP A OD2 1 
ATOM   256  N  N   . VAL A 1 65  ? -12.828 -3.652  34.74   1   12.708 ? 57   VAL A N   1 
ATOM   257  C  CA  . VAL A 1 65  ? -12.097 -4.931  34.734  1   11.749 ? 57   VAL A CA  1 
ATOM   258  C  C   . VAL A 1 65  ? -12.972 -5.997  35.403  1   11.955 ? 57   VAL A C   1 
ATOM   259  O  O   . VAL A 1 65  ? -13.698 -5.743  36.367  1   13.377 ? 57   VAL A O   1 
ATOM   260  C  CB  . VAL A 1 65  ? -10.815 -4.724  35.54   1   12.482 ? 57   VAL A CB  1 
ATOM   261  C  CG1 . VAL A 1 65  ? -9.961  -6.009  35.467  1   14.071 ? 57   VAL A CG1 1 
ATOM   262  C  CG2 . VAL A 1 65  ? -9.99   -3.566  34.991  1   13.409 ? 57   VAL A CG2 1 
ATOM   263  N  N   . MET A 1 66  ? -12.945 -7.192  34.797  1   12.607 ? 58   MET A N   1 
ATOM   264  C  CA  . MET A 1 66  ? -13.683 -8.311  35.378  1   13.424 ? 58   MET A CA  1 
ATOM   265  C  C   . MET A 1 66  ? -13.294 -8.555  36.817  1   14.35  ? 58   MET A C   1 
ATOM   266  O  O   . MET A 1 66  ? -12.101 -8.475  37.157  1   14.153 ? 58   MET A O   1 
ATOM   267  C  CB  . MET A 1 66  ? -13.388 -9.585  34.579  1   15.319 ? 58   MET A CB  1 
ATOM   268  C  CG  . MET A 1 66  ? -13.967 -9.485  33.178  1   18.461 ? 58   MET A CG  1 
ATOM   269  S  SD  . MET A 1 66  ? -13.601 -10.977 32.235  1   20.872 ? 58   MET A SD  1 
ATOM   270  C  CE  . MET A 1 66  ? -14.799 -12.081 33.007  1   22.006 ? 58   MET A CE  1 
ATOM   271  N  N   . THR A 1 67  ? -14.306 -8.85   37.661  1   13.919 ? 59   THR A N   1 
ATOM   272  C  CA  . THR A 1 67  ? -14.042 -9.205  39.05   1   13.844 ? 59   THR A CA  1 
ATOM   273  C  C   . THR A 1 67  ? -14.735 -10.503 39.421  1   14.745 ? 59   THR A C   1 
ATOM   274  O  O   . THR A 1 67  ? -15.767 -10.83  38.832  1   15.123 ? 59   THR A O   1 
ATOM   275  C  CB  . THR A 1 67  ? -14.436 -8.094  40.02   1   14.781 ? 59   THR A CB  1 
ATOM   276  O  OG1 . THR A 1 67  ? -15.84  -7.79   39.883  1   17.435 ? 59   THR A OG1 1 
ATOM   277  C  CG2 . THR A 1 67  ? -13.697 -6.79   39.708  1   16.739 ? 59   THR A CG2 1 
ATOM   278  N  N   . ARG A 1 68  ? -14.162 -11.159 40.423  1   15.641 ? 60   ARG A N   1 
ATOM   279  C  CA  . ARG A 1 68  ? -14.783 -12.309 41.065  1   15.084 ? 60   ARG A CA  1 
ATOM   280  C  C   . ARG A 1 68  ? -14.969 -11.923 42.508  1   16.865 ? 60   ARG A C   1 
ATOM   281  O  O   . ARG A 1 68  ? -14.118 -11.306 43.134  1   17.532 ? 60   ARG A O   1 
ATOM   282  C  CB  . ARG A 1 68  ? -13.944 -13.576 40.931  1   17.638 ? 60   ARG A CB  1 
ATOM   283  C  CG  . ARG A 1 68  ? -13.638 -13.953 39.486  1   18.978 ? 60   ARG A CG  1 
ATOM   284  C  CD  . ARG A 1 68  ? -12.946 -15.35  39.335  1   20.493 ? 60   ARG A CD  1 
ATOM   285  N  NE  . ARG A 1 68  ? -11.726 -15.58  40.132  1   21.374 ? 60   ARG A NE  1 
ATOM   286  C  CZ  . ARG A 1 68  ? -10.466 -15.239 39.789  1   22.616 ? 60   ARG A CZ  1 
ATOM   287  N  NH1 . ARG A 1 68  ? -10.25  -14.588 38.623  1   20.56  ? 60   ARG A NH1 1 
ATOM   288  N  NH2 . ARG A 1 68  ? -9.43   -15.577 40.595  1   17.608 ? 60   ARG A NH2 1 
ATOM   289  N  N   . GLY A 1 69  ? -16.068 -12.348 43.106  1   15.97  ? 61   GLY A N   1 
ATOM   290  C  CA  . GLY A 1 69  ? -16.319 -11.999 44.491  1   17.957 ? 61   GLY A CA  1 
ATOM   291  C  C   . GLY A 1 69  ? -16.923 -10.617 44.597  1   18.988 ? 61   GLY A C   1 
ATOM   292  O  O   . GLY A 1 69  ? -17.525 -10.163 43.623  1   25.502 ? 61   GLY A O   1 
ATOM   293  N  N   . THR A 1 70  ? -16.809 -9.975  45.757  1   19.783 ? 62   THR A N   1 
ATOM   294  C  CA  . THR A 1 70  ? -17.434 -8.678  45.965  1   21.501 ? 62   THR A CA  1 
ATOM   295  C  C   . THR A 1 70  ? -16.303 -7.698  46.28   1   17.706 ? 62   THR A C   1 
ATOM   296  O  O   . THR A 1 70  ? -15.583 -7.884  47.274  1   18.92  ? 62   THR A O   1 
ATOM   297  C  CB  . THR A 1 70  ? -18.447 -8.753  47.118  1   27.236 ? 62   THR A CB  1 
ATOM   298  O  OG1 . THR A 1 70  ? -19.529 -9.507  46.583  1   32.891 ? 62   THR A OG1 1 
ATOM   299  C  CG2 . THR A 1 70  ? -19.118 -7.423  47.394  1   27.423 ? 62   THR A CG2 1 
ATOM   300  N  N   . ILE A 1 71  ? -16.178 -6.673  45.434  1   17.198 ? 63   ILE A N   1 
ATOM   301  C  CA  . ILE A 1 71  ? -15.207 -5.619  45.685  1   17.806 ? 63   ILE A CA  1 
ATOM   302  C  C   . ILE A 1 71  ? -15.697 -4.799  46.879  1   17.683 ? 63   ILE A C   1 
ATOM   303  O  O   . ILE A 1 71  ? -16.808 -4.247  46.838  1   19.344 ? 63   ILE A O   1 
ATOM   304  C  CB  . ILE A 1 71  ? -14.991 -4.729  44.451  1   17.363 ? 63   ILE A CB  1 
ATOM   305  C  CG1 . ILE A 1 71  ? -14.508 -5.563  43.242  1   19.069 ? 63   ILE A CG1 1 
ATOM   306  C  CG2 . ILE A 1 71  ? -14.083 -3.538  44.791  1   17.695 ? 63   ILE A CG2 1 
ATOM   307  C  CD1 . ILE A 1 71  ? -13.08  -6.117  43.327  1   17.748 ? 63   ILE A CD1 1 
ATOM   308  N  N   . PRO A 1 72  ? -14.914 -4.676  47.973  1   14.681 ? 64   PRO A N   1 
ATOM   309  C  CA  . PRO A 1 72  ? -15.365 -3.899  49.126  1   15.646 ? 64   PRO A CA  1 
ATOM   310  C  C   . PRO A 1 72  ? -15.705 -2.467  48.733  1   18.528 ? 64   PRO A C   1 
ATOM   311  O  O   . PRO A 1 72  ? -14.926 -1.799  48.021  1   17.173 ? 64   PRO A O   1 
ATOM   312  C  CB  . PRO A 1 72  ? -14.146 -3.942  50.089  1   16.558 ? 64   PRO A CB  1 
ATOM   313  C  CG  . PRO A 1 72  ? -13.424 -5.215  49.713  1   18.243 ? 64   PRO A CG  1 
ATOM   314  C  CD  . PRO A 1 72  ? -13.618 -5.341  48.218  1   15.662 ? 64   PRO A CD  1 
ATOM   315  N  N   . LYS A 1 73  ? -16.88  -2.013  49.222  1   19.707 ? 65   LYS A N   1 
ATOM   316  C  CA  . LYS A 1 73  ? -17.289 -0.643  48.965  1   21.06  ? 65   LYS A CA  1 
ATOM   317  C  C   . LYS A 1 73  ? -16.388 0.373   49.669  1   18.517 ? 65   LYS A C   1 
ATOM   318  O  O   . LYS A 1 73  ? -16.325 1.535   49.259  1   20.55  ? 65   LYS A O   1 
ATOM   319  C  CB  . LYS A 1 73  ? -18.757 -0.484  49.378  1   27.387 ? 65   LYS A CB  1 
ATOM   320  C  CG  . LYS A 1 73  ? -19.775 -0.895  48.292  1   39.234 ? 65   LYS A CG  1 
ATOM   321  C  CD  . LYS A 1 73  ? -19.672 -0.231  46.919  1   42.735 ? 65   LYS A CD  1 
ATOM   322  C  CE  . LYS A 1 73  ? -20.93  0.243   46.243  1   53.581 ? 65   LYS A CE  1 
ATOM   323  N  NZ  . LYS A 1 73  ? -22.019 -0.734  46.289  1   57.408 ? 65   LYS A NZ  1 
ATOM   324  N  N   . GLU A 1 74  ? -15.601 -0.103  50.647  1   18.348 ? 66   GLU A N   1 
ATOM   325  C  CA  . GLU A 1 74  ? -14.727 0.773   51.406  1   17.826 ? 66   GLU A CA  1 
ATOM   326  C  C   . GLU A 1 74  ? -13.47  1.159   50.612  1   16.309 ? 66   GLU A C   1 
ATOM   327  O  O   . GLU A 1 74  ? -12.737 2.055   51.052  1   18.474 ? 66   GLU A O   1 
ATOM   328  C  CB  . GLU A 1 74  ? -14.252 0.132   52.698  1   17.181 ? 66   GLU A CB  1 
ATOM   329  C  CG  . GLU A 1 74  ? -15.392 -0.12   53.699  1   21.011 ? 66   GLU A CG  1 
ATOM   330  C  CD  . GLU A 1 74  ? -16.076 -1.463  53.553  1   20.495 ? 66   GLU A CD  1 
ATOM   331  O  OE1 . GLU A 1 74  ? -15.921 -2.191  52.566  1   20.261 ? 66   GLU A OE1 1 
ATOM   332  O  OE2 . GLU A 1 74  ? -16.861 -1.782  54.531  1   23.551 ? 66   GLU A OE2 1 
ATOM   333  N  N   . LEU A 1 75  ? -13.217 0.46    49.492  1   15.51  ? 67   LEU A N   1 
ATOM   334  C  CA  . LEU A 1 75  ? -12.02  0.813   48.702  1   15.336 ? 67   LEU A CA  1 
ATOM   335  C  C   . LEU A 1 75  ? -12.354 2.013   47.815  1   13.81  ? 67   LEU A C   1 
ATOM   336  O  O   . LEU A 1 75  ? -13.271 1.935   46.992  1   15.825 ? 67   LEU A O   1 
ATOM   337  C  CB  . LEU A 1 75  ? -11.545 -0.346  47.834  1   15.007 ? 67   LEU A CB  1 
ATOM   338  C  CG  . LEU A 1 75  ? -10.969 -1.512  48.638  1   14.822 ? 67   LEU A CG  1 
ATOM   339  C  CD1 . LEU A 1 75  ? -10.697 -2.646  47.698  1   15.822 ? 67   LEU A CD1 1 
ATOM   340  C  CD2 . LEU A 1 75  ? -9.667  -1.026  49.343  1   14.965 ? 67   LEU A CD2 1 
ATOM   341  N  N   . HIS A 1 76  ? -11.607 3.111   47.985  1   13.847 ? 68   HIS A N   1 
ATOM   342  C  CA  . HIS A 1 76  ? -11.858 4.349   47.266  1   12.833 ? 68   HIS A CA  1 
ATOM   343  C  C   . HIS A 1 76  ? -10.513 4.986   46.993  1   13.567 ? 68   HIS A C   1 
ATOM   344  O  O   . HIS A 1 76  ? -9.977  5.701   47.809  1   15.143 ? 68   HIS A O   1 
ATOM   345  C  CB  . HIS A 1 76  ? -12.708 5.274   48.176  1   15.712 ? 68   HIS A CB  1 
ATOM   346  C  CG  . HIS A 1 76  ? -13.325 6.402   47.401  1   16.231 ? 68   HIS A CG  1 
ATOM   347  N  ND1 . HIS A 1 76  ? -12.942 7.722   47.447  1   21.228 ? 68   HIS A ND1 1 
ATOM   348  C  CD2 . HIS A 1 76  ? -14.345 6.332   46.567  1   17.06  ? 68   HIS A CD2 1 
ATOM   349  C  CE1 . HIS A 1 76  ? -13.735 8.413   46.669  1   17.258 ? 68   HIS A CE1 1 
ATOM   350  N  NE2 . HIS A 1 76  ? -14.595 7.601   46.134  1   23.395 ? 68   HIS A NE2 1 
ATOM   351  N  N   . GLY A 1 77  ? -9.914  4.541   45.88   1   12.679 ? 69   GLY A N   1 
ATOM   352  C  CA  . GLY A 1 77  ? -8.539  4.937   45.639  1   12.652 ? 69   GLY A CA  1 
ATOM   353  C  C   . GLY A 1 77  ? -7.956  4.107   44.523  1   11.681 ? 69   GLY A C   1 
ATOM   354  O  O   . GLY A 1 77  ? -8.695  3.555   43.717  1   12.952 ? 69   GLY A O   1 
ATOM   355  N  N   . THR A 1 78  ? -6.611  4.157   44.435  1   12.37  ? 70   THR A N   1 
ATOM   356  C  CA  . THR A 1 78  ? -5.94   3.54    43.293  1   10.983 ? 70   THR A CA  1 
ATOM   357  C  C   . THR A 1 78  ? -4.76   2.749   43.823  1   11.317 ? 70   THR A C   1 
ATOM   358  O  O   . THR A 1 78  ? -3.978  3.262   44.613  1   12.508 ? 70   THR A O   1 
ATOM   359  C  CB  . THR A 1 78  ? -5.439  4.573   42.274  1   11.313 ? 70   THR A CB  1 
ATOM   360  O  OG1 . THR A 1 78  ? -6.454  5.513   42.015  1   12.511 ? 70   THR A OG1 1 
ATOM   361  C  CG2 . THR A 1 78  ? -5.005  3.899   40.972  1   10.547 ? 70   THR A CG2 1 
ATOM   362  N  N   . PHE A 1 79  ? -4.645  1.495   43.34   1   11.307 ? 71   PHE A N   1 
ATOM   363  C  CA  . PHE A 1 79  ? -3.44   0.712   43.59   1   12.08  ? 71   PHE A CA  1 
ATOM   364  C  C   . PHE A 1 79  ? -2.548  0.95    42.37   1   11.871 ? 71   PHE A C   1 
ATOM   365  O  O   . PHE A 1 79  ? -2.852  0.494   41.256  1   11.694 ? 71   PHE A O   1 
ATOM   366  C  CB  . PHE A 1 79  ? -3.814  -0.784  43.699  1   12.612 ? 71   PHE A CB  1 
ATOM   367  C  CG  . PHE A 1 79  ? -2.686  -1.771  43.927  1   12.161 ? 71   PHE A CG  1 
ATOM   368  C  CD1 . PHE A 1 79  ? -1.422  -1.413  44.392  1   12.468 ? 71   PHE A CD1 1 
ATOM   369  C  CD2 . PHE A 1 79  ? -2.972  -3.142  43.769  1   12.654 ? 71   PHE A CD2 1 
ATOM   370  C  CE1 . PHE A 1 79  ? -0.431  -2.394  44.621  1   12.441 ? 71   PHE A CE1 1 
ATOM   371  C  CE2 . PHE A 1 79  ? -2.006  -4.129  44.058  1   13.088 ? 71   PHE A CE2 1 
ATOM   372  C  CZ  . PHE A 1 79  ? -0.717  -3.745  44.459  1   13.82  ? 71   PHE A CZ  1 
ATOM   373  N  N   . TYR A 1 80  ? -1.455  1.681   42.598  1   10.659 ? 72   TYR A N   1 
ATOM   374  C  CA  . TYR A 1 80  ? -0.477  1.943   41.532  1   11.251 ? 72   TYR A CA  1 
ATOM   375  C  C   . TYR A 1 80  ? 0.7     1.004   41.744  1   13.011 ? 72   TYR A C   1 
ATOM   376  O  O   . TYR A 1 80  ? 1.267   1.018   42.836  1   14.671 ? 72   TYR A O   1 
ATOM   377  C  CB  . TYR A 1 80  ? 0.068   3.38    41.532  1   13.243 ? 72   TYR A CB  1 
ATOM   378  C  CG  . TYR A 1 80  ? -0.942  4.452   41.188  1   12.5   ? 72   TYR A CG  1 
ATOM   379  C  CD1 . TYR A 1 80  ? -1.156  4.832   39.854  1   12.909 ? 72   TYR A CD1 1 
ATOM   380  C  CD2 . TYR A 1 80  ? -1.599  5.166   42.194  1   13.53  ? 72   TYR A CD2 1 
ATOM   381  C  CE1 . TYR A 1 80  ? -2.052  5.863   39.545  1   13.208 ? 72   TYR A CE1 1 
ATOM   382  C  CE2 . TYR A 1 80  ? -2.443  6.249   41.901  1   13.586 ? 72   TYR A CE2 1 
ATOM   383  C  CZ  . TYR A 1 80  ? -2.693  6.581   40.55   1   12.901 ? 72   TYR A CZ  1 
ATOM   384  O  OH  . TYR A 1 80  ? -3.577  7.58    40.271  1   14.825 ? 72   TYR A OH  1 
ATOM   385  N  N   . ARG A 1 81  ? 1.098   0.252   40.708  1   12.467 ? 73   ARG A N   1 
ATOM   386  C  CA  . ARG A 1 81  ? 2.243   -0.65   40.822  1   12.064 ? 73   ARG A CA  1 
ATOM   387  C  C   . ARG A 1 81  ? 3.202   -0.332  39.696  1   12.265 ? 73   ARG A C   1 
ATOM   388  O  O   . ARG A 1 81  ? 2.762   0.001   38.614  1   14.209 ? 73   ARG A O   1 
ATOM   389  C  CB  . ARG A 1 81  ? 1.769   -2.09   40.652  1   19.109 ? 73   ARG A CB  1 
ATOM   390  C  CG  . ARG A 1 81  ? 2.867   -2.914  41.292  1   23.274 ? 73   ARG A CG  1 
ATOM   391  C  CD  . ARG A 1 81  ? 2.26    -3.857  42.301  1   15.682 ? 73   ARG A CD  1 
ATOM   392  N  NE  . ARG A 1 81  ? 3.178   -4.956  42.081  1   14.565 ? 73   ARG A NE  1 
ATOM   393  C  CZ  . ARG A 1 81  ? 4.346   -5.054  42.746  1   12.993 ? 73   ARG A CZ  1 
ATOM   394  N  NH1 . ARG A 1 81  ? 4.646   -4.309  43.817  1   12.583 ? 73   ARG A NH1 1 
ATOM   395  N  NH2 . ARG A 1 81  ? 5.247   -5.932  42.319  1   14.255 ? 73   ARG A NH2 1 
ATOM   396  N  N   . ILE A 1 82  ? 4.505   -0.413  39.966  1   11.015 ? 74   ILE A N   1 
ATOM   397  C  CA  . ILE A 1 82  ? 5.471   -0.073  38.931  1   12.664 ? 74   ILE A CA  1 
ATOM   398  C  C   . ILE A 1 82  ? 6.352   -1.29   38.676  1   12.003 ? 74   ILE A C   1 
ATOM   399  O  O   . ILE A 1 82  ? 6.635   -2.075  39.583  1   13.133 ? 74   ILE A O   1 
ATOM   400  C  CB  . ILE A 1 82  ? 6.247   1.193   39.325  1   10.792 ? 74   ILE A CB  1 
ATOM   401  C  CG1 . ILE A 1 82  ? 6.952   1.827   38.117  1   12.312 ? 74   ILE A CG1 1 
ATOM   402  C  CG2 . ILE A 1 82  ? 7.222   0.972   40.487  1   12.824 ? 74   ILE A CG2 1 
ATOM   403  C  CD1 . ILE A 1 82  ? 7.407   3.265   38.373  1   14.035 ? 74   ILE A CD1 1 
ATOM   404  N  N   . MET A 1 83  ? 6.739   -1.426  37.404  1   11.656 ? 75   MET A N   1 
ATOM   405  C  CA  . MET A 1 83  ? 7.438   -2.626  36.957  1   11.904 ? 75   MET A CA  1 
ATOM   406  C  C   . MET A 1 83  ? 8.499   -2.24   35.965  1   12.422 ? 75   MET A C   1 
ATOM   407  O  O   . MET A 1 83  ? 8.367   -1.299  35.17   1   11.741 ? 75   MET A O   1 
ATOM   408  C  CB  . MET A 1 83  ? 6.477   -3.54   36.156  1   13.6   ? 75   MET A CB  1 
ATOM   409  C  CG  . MET A 1 83  ? 5.306   -4.118  36.965  1   15.193 ? 75   MET A CG  1 
ATOM   410  S  SD  . MET A 1 83  ? 3.802   -4.214  35.953  1   17.124 ? 75   MET A SD  1 
ATOM   411  C  CE  . MET A 1 83  ? 3.324   -2.606  36.507  1   14.754 ? 75   MET A CE  1 
ATOM   412  N  N   . PRO A 1 84  ? 9.607   -3.011  35.915  1   11.496 ? 76   PRO A N   1 
ATOM   413  C  CA  . PRO A 1 84  ? 10.61   -2.879  34.854  1   11.252 ? 76   PRO A CA  1 
ATOM   414  C  C   . PRO A 1 84  ? 10.164  -3.68   33.64   1   11.819 ? 76   PRO A C   1 
ATOM   415  O  O   . PRO A 1 84  ? 9.872   -4.882  33.775  1   14.037 ? 76   PRO A O   1 
ATOM   416  C  CB  . PRO A 1 84  ? 11.881  -3.488  35.543  1   11.374 ? 76   PRO A CB  1 
ATOM   417  C  CG  . PRO A 1 84  ? 11.305  -4.606  36.461  1   12.993 ? 76   PRO A CG  1 
ATOM   418  C  CD  . PRO A 1 84  ? 9.93    -4.082  36.893  1   13.187 ? 76   PRO A CD  1 
ATOM   419  N  N   . ASP A 1 85  ? 10.085  -3.016  32.481  1   11.39  ? 77   ASP A N   1 
ATOM   420  C  CA  . ASP A 1 85  ? 9.641   -3.75   31.294  1   12.434 ? 77   ASP A CA  1 
ATOM   421  C  C   . ASP A 1 85  ? 10.303  -3.075  30.105  1   11.52  ? 77   ASP A C   1 
ATOM   422  O  O   . ASP A 1 85  ? 9.698   -2.229  29.441  1   13.282 ? 77   ASP A O   1 
ATOM   423  C  CB  . ASP A 1 85  ? 8.108   -3.633  31.19   1   13.626 ? 77   ASP A CB  1 
ATOM   424  C  CG  . ASP A 1 85  ? 7.359   -4.639  30.316  1   15.916 ? 77   ASP A CG  1 
ATOM   425  O  OD1 . ASP A 1 85  ? 7.957   -5.605  29.788  1   15.736 ? 77   ASP A OD1 1 
ATOM   426  O  OD2 . ASP A 1 85  ? 6.118   -4.419  30.202  1   17.028 ? 77   ASP A OD2 1 
ATOM   427  N  N   . TYR A 1 86  ? 11.555  -3.457  29.81   1   12.921 ? 78   TYR A N   1 
ATOM   428  C  CA  . TYR A 1 86  ? 12.277  -2.801  28.719  1   13.061 ? 78   TYR A CA  1 
ATOM   429  C  C   . TYR A 1 86  ? 11.378  -2.624  27.483  1   12.259 ? 78   TYR A C   1 
ATOM   430  O  O   . TYR A 1 86  ? 10.789  -3.613  26.992  1   13.382 ? 78   TYR A O   1 
ATOM   431  C  CB  . TYR A 1 86  ? 13.45   -3.708  28.323  1   15.266 ? 78   TYR A CB  1 
ATOM   432  C  CG  . TYR A 1 86  ? 14.762  -3.402  29.035  1   14.096 ? 78   TYR A CG  1 
ATOM   433  C  CD1 . TYR A 1 86  ? 15.394  -2.162  28.815  1   14.17  ? 78   TYR A CD1 1 
ATOM   434  C  CD2 . TYR A 1 86  ? 15.356  -4.355  29.851  1   14.436 ? 78   TYR A CD2 1 
ATOM   435  C  CE1 . TYR A 1 86  ? 16.645  -1.893  29.38   1   15.308 ? 78   TYR A CE1 1 
ATOM   436  C  CE2 . TYR A 1 86  ? 16.633  -4.105  30.382  1   13.169 ? 78   TYR A CE2 1 
ATOM   437  C  CZ  . TYR A 1 86  ? 17.248  -2.88   30.14   1   13.835 ? 78   TYR A CZ  1 
ATOM   438  O  OH  . TYR A 1 86  ? 18.527  -2.689  30.623  1   15.841 ? 78   TYR A OH  1 
ATOM   439  N  N   . ALA A 1 87  ? 11.311  -1.379  26.976  1   12.249 ? 79   ALA A N   1 
ATOM   440  C  CA  . ALA A 1 87  ? 10.406  -1.069  25.875  1   13.28  ? 79   ALA A CA  1 
ATOM   441  C  C   . ALA A 1 87  ? 10.978  -1.477  24.521  1   14.844 ? 79   ALA A C   1 
ATOM   442  O  O   . ALA A 1 87  ? 10.233  -1.819  23.603  1   16.022 ? 79   ALA A O   1 
ATOM   443  C  CB  . ALA A 1 87  ? 10.037  0.421   25.94   1   13.266 ? 79   ALA A CB  1 
ATOM   444  N  N   . GLN A 1 88  ? 12.304  -1.414  24.408  1   14.96  ? 80   GLN A N   1 
ATOM   445  C  CA  . GLN A 1 88  ? 13.053  -1.898  23.245  1   14.576 ? 80   GLN A CA  1 
ATOM   446  C  C   . GLN A 1 88  ? 14.003  -2.987  23.706  1   15.506 ? 80   GLN A C   1 
ATOM   447  O  O   . GLN A 1 88  ? 14.441  -2.989  24.859  1   15.08  ? 80   GLN A O   1 
ATOM   448  C  CB  . GLN A 1 88  ? 13.885  -0.763  22.634  1   15.58  ? 80   GLN A CB  1 
ATOM   449  C  CG  . GLN A 1 88  ? 13.036  0.402   22.109  1   15.58  ? 80   GLN A CG  1 
ATOM   450  C  CD  . GLN A 1 88  ? 12.07   0.035   20.993  1   15.378 ? 80   GLN A CD  1 
ATOM   451  O  OE1 . GLN A 1 88  ? 10.878  0.372   21.014  1   16.216 ? 80   GLN A OE1 1 
ATOM   452  N  NE2 . GLN A 1 88  ? 12.542  -0.67   19.96   1   16.705 ? 80   GLN A NE2 1 
ATOM   453  N  N   . PRO A 1 89  ? 14.365  -3.953  22.827  1   14.939 ? 81   PRO A N   1 
ATOM   454  C  CA  . PRO A 1 89  ? 15.266  -5.035  23.248  1   15.316 ? 81   PRO A CA  1 
ATOM   455  C  C   . PRO A 1 89  ? 16.611  -4.393  23.643  1   13.977 ? 81   PRO A C   1 
ATOM   456  O  O   . PRO A 1 89  ? 17.148  -3.591  22.876  1   13.82  ? 81   PRO A O   1 
ATOM   457  C  CB  . PRO A 1 89  ? 15.366  -5.913  21.962  1   16.666 ? 81   PRO A CB  1 
ATOM   458  C  CG  . PRO A 1 89  ? 14.871  -5.026  20.859  1   17.179 ? 81   PRO A CG  1 
ATOM   459  C  CD  . PRO A 1 89  ? 13.847  -4.097  21.438  1   15.428 ? 81   PRO A CD  1 
ATOM   460  N  N   . PRO A 1 90  ? 17.161  -4.709  24.847  1   14.755 ? 82   PRO A N   1 
ATOM   461  C  CA  . PRO A 1 90  ? 18.249  -3.869  25.414  1   14.725 ? 82   PRO A CA  1 
ATOM   462  C  C   . PRO A 1 90  ? 19.659  -4.251  24.942  1   15.934 ? 82   PRO A C   1 
ATOM   463  O  O   . PRO A 1 90  ? 20.516  -4.574  25.762  1   16.738 ? 82   PRO A O   1 
ATOM   464  C  CB  . PRO A 1 90  ? 18.042  -4.063  26.925  1   15.825 ? 82   PRO A CB  1 
ATOM   465  C  CG  . PRO A 1 90  ? 17.503  -5.483  27.043  1   14.995 ? 82   PRO A CG  1 
ATOM   466  C  CD  . PRO A 1 90  ? 16.499  -5.521  25.89   1   13.558 ? 82   PRO A CD  1 
ATOM   467  N  N   . THR A 1 91  ? 19.844  -4.231  23.619  1   15.238 ? 83   THR A N   1 
ATOM   468  C  CA  . THR A 1 91  ? 21.002  -4.897  23.013  1   15.821 ? 83   THR A CA  1 
ATOM   469  C  C   . THR A 1 91  ? 22.246  -4.005  22.908  1   16.631 ? 83   THR A C   1 
ATOM   470  O  O   . THR A 1 91  ? 23.236  -4.492  22.355  1   18.205 ? 83   THR A O   1 
ATOM   471  C  CB  . THR A 1 91  ? 20.601  -5.407  21.617  1   19.077 ? 83   THR A CB  1 
ATOM   472  O  OG1 . THR A 1 91  ? 20.095  -4.289  20.897  1   20.437 ? 83   THR A OG1 1 
ATOM   473  C  CG2 . THR A 1 91  ? 19.626  -6.565  21.69   1   24.341 ? 83   THR A CG2 1 
ATOM   474  N  N   . TYR A 1 92  ? 22.223  -2.742  23.376  1   14.722 ? 84   TYR A N   1 
ATOM   475  C  CA  . TYR A 1 92  ? 23.321  -1.818  23.073  1   15.553 ? 84   TYR A CA  1 
ATOM   476  C  C   . TYR A 1 92  ? 24.669  -2.347  23.6    1   15.27  ? 84   TYR A C   1 
ATOM   477  O  O   . TYR A 1 92  ? 25.687  -2.309  22.851  1   16.902 ? 84   TYR A O   1 
ATOM   478  C  CB  . TYR A 1 92  ? 23.059  -0.4    23.602  1   15.16  ? 84   TYR A CB  1 
ATOM   479  C  CG  . TYR A 1 92  ? 24.206  0.507   23.192  1   17.647 ? 84   TYR A CG  1 
ATOM   480  C  CD1 . TYR A 1 92  ? 24.356  0.874   21.848  1   17.385 ? 84   TYR A CD1 1 
ATOM   481  C  CD2 . TYR A 1 92  ? 25.21   0.847   24.11   1   17.2   ? 84   TYR A CD2 1 
ATOM   482  C  CE1 . TYR A 1 92  ? 25.5    1.557   21.421  1   18.606 ? 84   TYR A CE1 1 
ATOM   483  C  CE2 . TYR A 1 92  ? 26.326  1.573   23.687  1   18.92  ? 84   TYR A CE2 1 
ATOM   484  C  CZ  . TYR A 1 92  ? 26.436  1.943   22.36   1   20.309 ? 84   TYR A CZ  1 
ATOM   485  O  OH  . TYR A 1 92  ? 27.542  2.631   21.883  1   24.447 ? 84   TYR A OH  1 
ATOM   486  N  N   . TYR A 1 93  ? 24.713  -2.812  24.853  1   14.858 ? 85   TYR A N   1 
ATOM   487  C  CA  . TYR A 1 93  ? 26.01   -3.193  25.439  1   15.045 ? 85   TYR A CA  1 
ATOM   488  C  C   . TYR A 1 93  ? 26.08   -4.696  25.601  1   16.488 ? 85   TYR A C   1 
ATOM   489  O  O   . TYR A 1 93  ? 25.267  -5.279  26.298  1   17.828 ? 85   TYR A O   1 
ATOM   490  C  CB  . TYR A 1 93  ? 26.148  -2.501  26.787  1   17.279 ? 85   TYR A CB  1 
ATOM   491  C  CG  . TYR A 1 93  ? 27.513  -2.692  27.439  1   16.736 ? 85   TYR A CG  1 
ATOM   492  C  CD1 . TYR A 1 93  ? 28.649  -2.116  26.849  1   18.829 ? 85   TYR A CD1 1 
ATOM   493  C  CD2 . TYR A 1 93  ? 27.654  -3.467  28.568  1   15.667 ? 85   TYR A CD2 1 
ATOM   494  C  CE1 . TYR A 1 93  ? 29.904  -2.274  27.436  1   16.732 ? 85   TYR A CE1 1 
ATOM   495  C  CE2 . TYR A 1 93  ? 28.905  -3.616  29.183  1   16.595 ? 85   TYR A CE2 1 
ATOM   496  C  CZ  . TYR A 1 93  ? 30.005  -2.982  28.626  1   19.151 ? 85   TYR A CZ  1 
ATOM   497  O  OH  . TYR A 1 93  ? 31.212  -3.116  29.238  1   19.577 ? 85   TYR A OH  1 
ATOM   498  N  N   . LYS A 1 94  ? 27.105  -5.314  24.967  1   17.444 ? 86   LYS A N   1 
ATOM   499  C  CA  . LYS A 1 94  ? 27.342  -6.751  25.115  1   17.794 ? 86   LYS A CA  1 
ATOM   500  C  C   . LYS A 1 94  ? 26.084  -7.54   24.754  1   16.957 ? 86   LYS A C   1 
ATOM   501  O  O   . LYS A 1 94  ? 25.78   -8.555  25.374  1   19.054 ? 86   LYS A O   1 
ATOM   502  C  CB  . LYS A 1 94  ? 27.999  -7.092  26.464  1   17.651 ? 86   LYS A CB  1 
ATOM   503  C  CG  . LYS A 1 94  ? 29.393  -6.433  26.703  1   19.102 ? 86   LYS A CG  1 
ATOM   504  C  CD  . LYS A 1 94  ? 30.048  -6.901  28.01   1   18.503 ? 86   LYS A CD  1 
ATOM   505  C  CE  . LYS A 1 94  ? 31.456  -6.341  28.004  1   24.262 ? 86   LYS A CE  1 
ATOM   506  N  NZ  . LYS A 1 94  ? 32.196  -6.725  29.224  1   26.131 ? 86   LYS A NZ  1 
ATOM   507  N  N   . GLY A 1 95  ? 25.332  -7.058  23.748  1   18.968 ? 87   GLY A N   1 
ATOM   508  C  CA  . GLY A 1 95  ? 24.085  -7.691  23.325  1   19.283 ? 87   GLY A CA  1 
ATOM   509  C  C   . GLY A 1 95  ? 22.992  -7.77   24.41   1   18.892 ? 87   GLY A C   1 
ATOM   510  O  O   . GLY A 1 95  ? 22.08   -8.605  24.323  1   21.043 ? 87   GLY A O   1 
ATOM   511  N  N   . GLY A 1 96  ? 23.132  -6.938  25.454  1   17.933 ? 88   GLY A N   1 
ATOM   512  C  CA  . GLY A 1 96  ? 22.215  -7.004  26.599  1   17.749 ? 88   GLY A CA  1 
ATOM   513  C  C   . GLY A 1 96  ? 22.454  -8.19   27.527  1   17.944 ? 88   GLY A C   1 
ATOM   514  O  O   . GLY A 1 96  ? 21.634  -8.412  28.418  1   17.664 ? 88   GLY A O   1 
ATOM   515  N  N   . GLU A 1 97  ? 23.6    -8.903  27.403  1   18.026 ? 89   GLU A N   1 
ATOM   516  C  CA  . GLU A 1 97  ? 23.827  -10.133 28.17   1   20.709 ? 89   GLU A CA  1 
ATOM   517  C  C   . GLU A 1 97  ? 23.853  -9.879  29.69   1   17.759 ? 89   GLU A C   1 
ATOM   518  O  O   . GLU A 1 97  ? 23.512  -10.777 30.475  1   18.461 ? 89   GLU A O   1 
ATOM   519  C  CB  . GLU A 1 97  ? 25.203  -10.677 27.741  1   26.284 ? 89   GLU A CB  1 
ATOM   520  C  CG  . GLU A 1 97  ? 25.705  -11.902 28.51   1   38.969 ? 89   GLU A CG  1 
ATOM   521  C  CD  . GLU A 1 97  ? 27.201  -12.219 28.561  1   58.363 ? 89   GLU A CD  1 
ATOM   522  O  OE1 . GLU A 1 97  ? 28.072  -11.376 28.184  1   53.805 ? 89   GLU A OE1 1 
ATOM   523  O  OE2 . GLU A 1 97  ? 27.498  -13.357 29.014  1   65.36  ? 89   GLU A OE2 1 
ATOM   524  N  N   . LEU A 1 98  ? 24.24   -8.653  30.098  1   16.771 ? 90   LEU A N   1 
ATOM   525  C  CA  . LEU A 1 98  ? 24.394  -8.342  31.515  1   17.892 ? 90   LEU A CA  1 
ATOM   526  C  C   . LEU A 1 98  ? 23.3    -7.382  32.021  1   17.236 ? 90   LEU A C   1 
ATOM   527  O  O   . LEU A 1 98  ? 23.472  -6.777  33.095  1   16.606 ? 90   LEU A O   1 
ATOM   528  C  CB  . LEU A 1 98  ? 25.798  -7.772  31.737  1   20.202 ? 90   LEU A CB  1 
ATOM   529  C  CG  . LEU A 1 98  ? 26.95   -8.741  31.47   1   20.479 ? 90   LEU A CG  1 
ATOM   530  C  CD1 . LEU A 1 98  ? 28.276  -8.01   31.686  1   22.445 ? 90   LEU A CD1 1 
ATOM   531  C  CD2 . LEU A 1 98  ? 26.869  -10.047 32.304  1   22.337 ? 90   LEU A CD2 1 
ATOM   532  N  N   . ASN A 1 99  ? 22.183  -7.255  31.255  1   15.63  ? 91   ASN A N   1 
ATOM   533  C  CA  . ASN A 1 99  ? 21.039  -6.522  31.81   1   16.422 ? 91   ASN A CA  1 
ATOM   534  C  C   . ASN A 1 99  ? 20.605  -7.14   33.145  1   16.119 ? 91   ASN A C   1 
ATOM   535  O  O   . ASN A 1 99  ? 20.644  -8.351  33.33   1   18.545 ? 91   ASN A O   1 
ATOM   536  C  CB  . ASN A 1 99  ? 19.92   -6.343  30.774  1   16.235 ? 91   ASN A CB  1 
ATOM   537  C  CG  . ASN A 1 99  ? 18.961  -7.506  30.75   1   20.193 ? 91   ASN A CG  1 
ATOM   538  O  OD1 . ASN A 1 99  ? 18.081  -7.602  31.619  1   19.768 ? 91   ASN A OD1 1 
ATOM   539  N  ND2 . ASN A 1 99  ? 19.11   -8.449  29.811  1   19.205 ? 91   ASN A ND2 1 
ATOM   540  N  N   . ALA A 1 100 ? 20.181  -6.266  34.09   1   15.547 ? 92   ALA A N   1 
ATOM   541  C  CA  . ALA A 1 100 ? 19.779  -6.695  35.407  1   14.607 ? 92   ALA A CA  1 
ATOM   542  C  C   . ALA A 1 100 ? 18.253  -6.643  35.515  1   15.749 ? 92   ALA A C   1 
ATOM   543  O  O   . ALA A 1 100 ? 17.614  -5.844  34.814  1   14.771 ? 92   ALA A O   1 
ATOM   544  C  CB  . ALA A 1 100 ? 20.411  -5.761  36.451  1   16.083 ? 92   ALA A CB  1 
ATOM   545  N  N   . PRO A 1 101 ? 17.622  -7.436  36.404  1   13.671 ? 93   PRO A N   1 
ATOM   546  C  CA  . PRO A 1 101 ? 16.16   -7.39   36.576  1   14.505 ? 93   PRO A CA  1 
ATOM   547  C  C   . PRO A 1 101 ? 15.633  -6.033  37.015  1   13.858 ? 93   PRO A C   1 
ATOM   548  O  O   . PRO A 1 101 ? 14.456  -5.744  36.757  1   15.485 ? 93   PRO A O   1 
ATOM   549  C  CB  . PRO A 1 101 ? 15.863  -8.472  37.595  1   14.418 ? 93   PRO A CB  1 
ATOM   550  C  CG  . PRO A 1 101 ? 17.185  -8.675  38.343  1   14.522 ? 93   PRO A CG  1 
ATOM   551  C  CD  . PRO A 1 101 ? 18.236  -8.474  37.268  1   14.696 ? 93   PRO A CD  1 
ATOM   552  N  N   . ILE A 1 102 ? 16.51   -5.207  37.598  1   13.632 ? 94   ILE A N   1 
ATOM   553  C  CA  . ILE A 1 102 ? 16.127  -3.864  38.05   1   13.617 ? 94   ILE A CA  1 
ATOM   554  C  C   . ILE A 1 102 ? 16.34   -2.791  36.983  1   14.661 ? 94   ILE A C   1 
ATOM   555  O  O   . ILE A 1 102 ? 16.23   -1.607  37.297  1   12.797 ? 94   ILE A O   1 
ATOM   556  C  CB  . ILE A 1 102 ? 16.82   -3.509  39.39   1   14.029 ? 94   ILE A CB  1 
ATOM   557  C  CG1 . ILE A 1 102 ? 18.376  -3.511  39.242  1   14.636 ? 94   ILE A CG1 1 
ATOM   558  C  CG2 . ILE A 1 102 ? 16.368  -4.47   40.494  1   15.065 ? 94   ILE A CG2 1 
ATOM   559  C  CD1 . ILE A 1 102 ? 19.118  -3.05   40.491  1   13.941 ? 94   ILE A CD1 1 
ATOM   560  N  N   . ASP A 1 103 ? 16.746  -3.165  35.774  1   12.624 ? 95   ASP A N   1 
ATOM   561  C  CA  . ASP A 1 103 ? 17.092  -2.167  34.76   1   12.431 ? 95   ASP A CA  1 
ATOM   562  C  C   . ASP A 1 103 ? 15.904  -1.606  33.968  1   13.527 ? 95   ASP A C   1 
ATOM   563  O  O   . ASP A 1 103 ? 15.947  -0.408  33.61   1   13.986 ? 95   ASP A O   1 
ATOM   564  C  CB  . ASP A 1 103 ? 18.038  -2.778  33.739  1   12.993 ? 95   ASP A CB  1 
ATOM   565  C  CG  . ASP A 1 103 ? 19.532  -2.531  34.01   1   15.357 ? 95   ASP A CG  1 
ATOM   566  O  OD1 . ASP A 1 103 ? 19.875  -1.39   34.373  1   15.853 ? 95   ASP A OD1 1 
ATOM   567  O  OD2 . ASP A 1 103 ? 20.322  -3.483  33.818  1   15.185 ? 95   ASP A OD2 1 
ATOM   568  N  N   . GLY A 1 104 ? 14.92   -2.456  33.62   1   12.827 ? 96   GLY A N   1 
ATOM   569  C  CA  . GLY A 1 104 ? 14.085  -2.127  32.447  1   13.708 ? 96   GLY A CA  1 
ATOM   570  C  C   . GLY A 1 104 ? 13.2    -0.879  32.626  1   12.58  ? 96   GLY A C   1 
ATOM   571  O  O   . GLY A 1 104 ? 12.824  -0.507  33.73   1   12.859 ? 96   GLY A O   1 
ATOM   572  N  N   . ASP A 1 105 ? 12.835  -0.272  31.494  1   11.987 ? 97   ASP A N   1 
ATOM   573  C  CA  . ASP A 1 105 ? 12.01   0.949   31.491  1   12.515 ? 97   ASP A CA  1 
ATOM   574  C  C   . ASP A 1 105 ? 10.791  0.802   32.405  1   11.083 ? 97   ASP A C   1 
ATOM   575  O  O   . ASP A 1 105 ? 10.033  -0.171  32.354  1   12.144 ? 97   ASP A O   1 
ATOM   576  C  CB  . ASP A 1 105 ? 11.485  1.264   30.088  1   11.836 ? 97   ASP A CB  1 
ATOM   577  C  CG  . ASP A 1 105 ? 12.652  1.433   29.139  1   11.971 ? 97   ASP A CG  1 
ATOM   578  O  OD1 . ASP A 1 105 ? 13.435  2.361   29.36   1   13.192 ? 97   ASP A OD1 1 
ATOM   579  O  OD2 . ASP A 1 105 ? 12.847  0.586   28.258  1   13.403 ? 97   ASP A OD2 1 
ATOM   580  N  N   . GLY A 1 106 ? 10.584  1.837   33.246  1   10.86  ? 98   GLY A N   1 
ATOM   581  C  CA  . GLY A 1 106 ? 9.474   1.798   34.208  1   10.949 ? 98   GLY A CA  1 
ATOM   582  C  C   . GLY A 1 106 ? 8.119   1.955   33.52   1   11.226 ? 98   GLY A C   1 
ATOM   583  O  O   . GLY A 1 106 ? 7.948   2.828   32.657  1   11.466 ? 98   GLY A O   1 
ATOM   584  N  N   . THR A 1 107 ? 7.193   1.061   33.903  1   10.876 ? 99   THR A N   1 
ATOM   585  C  CA  . THR A 1 107 ? 5.806   1.163   33.44   1   10.915 ? 99   THR A CA  1 
ATOM   586  C  C   . THR A 1 107 ? 4.9     1.044   34.669  1   11.331 ? 99   THR A C   1 
ATOM   587  O  O   . THR A 1 107 ? 5.159   0.186   35.536  1   11.541 ? 99   THR A O   1 
ATOM   588  C  CB  . THR A 1 107 ? 5.536   0.1     32.36   1   11.289 ? 99   THR A CB  1 
ATOM   589  O  OG1 . THR A 1 107 ? 4.151   0.287   32.012  1   12.586 ? 99   THR A OG1 1 
ATOM   590  C  CG2 . THR A 1 107 ? 5.752   -1.335  32.827  1   12.901 ? 99   THR A CG2 1 
ATOM   591  N  N   . VAL A 1 108 ? 3.892   1.916   34.727  1   11.842 ? 100  VAL A N   1 
ATOM   592  C  CA  . VAL A 1 108 ? 2.979   2.007   35.861  1   12.856 ? 100  VAL A CA  1 
ATOM   593  C  C   . VAL A 1 108 ? 1.667   1.349   35.477  1   11.46  ? 100  VAL A C   1 
ATOM   594  O  O   . VAL A 1 108 ? 1.08    1.677   34.431  1   12.013 ? 100  VAL A O   1 
ATOM   595  C  CB  . VAL A 1 108 ? 2.773   3.461   36.311  1   12.008 ? 100  VAL A CB  1 
ATOM   596  C  CG1 . VAL A 1 108 ? 1.73    3.605   37.413  1   13.187 ? 100  VAL A CG1 1 
ATOM   597  C  CG2 . VAL A 1 108 ? 4.091   4.083   36.786  1   13.192 ? 100  VAL A CG2 1 
ATOM   598  N  N   . ALA A 1 109 ? 1.224   0.424   36.335  1   11.314 ? 101  ALA A N   1 
ATOM   599  C  CA  . ALA A 1 109 ? -0.148  -0.079  36.246  1   13.41  ? 101  ALA A CA  1 
ATOM   600  C  C   . ALA A 1 109 ? -0.96   0.572   37.35   1   13.046 ? 101  ALA A C   1 
ATOM   601  O  O   . ALA A 1 109 ? -0.549  0.61    38.512  1   15.594 ? 101  ALA A O   1 
ATOM   602  C  CB  . ALA A 1 109 ? -0.191  -1.589  36.412  1   15.245 ? 101  ALA A CB  1 
ATOM   603  N  N   . ALA A 1 110 ? -2.142  1.03    36.991  1   12.251 ? 102  ALA A N   1 
ATOM   604  C  CA  . ALA A 1 110 ? -3.06   1.636   37.947  1   11.135 ? 102  ALA A CA  1 
ATOM   605  C  C   . ALA A 1 110 ? -4.349  0.841   37.959  1   11.18  ? 102  ALA A C   1 
ATOM   606  O  O   . ALA A 1 110 ? -4.944  0.602   36.891  1   11.133 ? 102  ALA A O   1 
ATOM   607  C  CB  . ALA A 1 110 ? -3.353  3.083   37.518  1   11.974 ? 102  ALA A CB  1 
ATOM   608  N  N   . PHE A 1 111 ? -4.827  0.504   39.169  1   12.273 ? 103  PHE A N   1 
ATOM   609  C  CA  . PHE A 1 111 ? -6.115  -0.173  39.341  1   11.156 ? 103  PHE A CA  1 
ATOM   610  C  C   . PHE A 1 111 ? -6.936  0.703   40.253  1   11.531 ? 103  PHE A C   1 
ATOM   611  O  O   . PHE A 1 111 ? -6.634  0.843   41.428  1   11.992 ? 103  PHE A O   1 
ATOM   612  C  CB  . PHE A 1 111 ? -5.907  -1.539  40.038  1   11.263 ? 103  PHE A CB  1 
ATOM   613  C  CG  . PHE A 1 111 ? -5.048  -2.506  39.231  1   11.37  ? 103  PHE A CG  1 
ATOM   614  C  CD1 . PHE A 1 111 ? -3.667  -2.53   39.388  1   12.363 ? 103  PHE A CD1 1 
ATOM   615  C  CD2 . PHE A 1 111 ? -5.637  -3.419  38.366  1   11.694 ? 103  PHE A CD2 1 
ATOM   616  C  CE1 . PHE A 1 111 ? -2.882  -3.402  38.651  1   12.921 ? 103  PHE A CE1 1 
ATOM   617  C  CE2 . PHE A 1 111 ? -4.843  -4.311  37.627  1   14.487 ? 103  PHE A CE2 1 
ATOM   618  C  CZ  . PHE A 1 111 ? -3.469  -4.306  37.801  1   14.846 ? 103  PHE A CZ  1 
ATOM   619  N  N   . ARG A 1 112 ? -7.935  1.391   39.657  1   11.767 ? 104  ARG A N   1 
ATOM   620  C  CA  . ARG A 1 112 ? -8.713  2.365   40.442  1   11.34  ? 104  ARG A CA  1 
ATOM   621  C  C   . ARG A 1 112 ? -10.038 1.75    40.857  1   12.286 ? 104  ARG A C   1 
ATOM   622  O  O   . ARG A 1 112 ? -10.79  1.277   40.002  1   12.651 ? 104  ARG A O   1 
ATOM   623  C  CB  . ARG A 1 112 ? -8.934  3.631   39.591  1   11.95  ? 104  ARG A CB  1 
ATOM   624  C  CG  . ARG A 1 112 ? -9.7    4.681   40.42   1   12.295 ? 104  ARG A CG  1 
ATOM   625  C  CD  . ARG A 1 112 ? -9.557  6.061   39.755  1   12.292 ? 104  ARG A CD  1 
ATOM   626  N  NE  . ARG A 1 112 ? -8.197  6.554   40.016  1   13.109 ? 104  ARG A NE  1 
ATOM   627  C  CZ  . ARG A 1 112 ? -7.755  7.71    39.498  1   12.526 ? 104  ARG A CZ  1 
ATOM   628  N  NH1 . ARG A 1 112 ? -8.527  8.465   38.738  1   14.036 ? 104  ARG A NH1 1 
ATOM   629  N  NH2 . ARG A 1 112 ? -6.489  8.097   39.688  1   13.565 ? 104  ARG A NH2 1 
ATOM   630  N  N   . PHE A 1 113 ? -10.262 1.785   42.161  1   12.359 ? 105  PHE A N   1 
ATOM   631  C  CA  . PHE A 1 113 ? -11.483 1.255   42.771  1   11.725 ? 105  PHE A CA  1 
ATOM   632  C  C   . PHE A 1 113 ? -12.37  2.42    43.214  1   12.683 ? 105  PHE A C   1 
ATOM   633  O  O   . PHE A 1 113 ? -11.975 3.28    44.005  1   14.07  ? 105  PHE A O   1 
ATOM   634  C  CB  . PHE A 1 113 ? -11.024 0.543   44.045  1   12.979 ? 105  PHE A CB  1 
ATOM   635  C  CG  . PHE A 1 113 ? -10.199 -0.716  43.831  1   12.973 ? 105  PHE A CG  1 
ATOM   636  C  CD1 . PHE A 1 113 ? -8.847  -0.609  43.47   1   12.807 ? 105  PHE A CD1 1 
ATOM   637  C  CD2 . PHE A 1 113 ? -10.76  -1.98   44.003  1   15.697 ? 105  PHE A CD2 1 
ATOM   638  C  CE1 . PHE A 1 113 ? -8.084  -1.764  43.221  1   13.785 ? 105  PHE A CE1 1 
ATOM   639  C  CE2 . PHE A 1 113 ? -9.994  -3.139  43.767  1   15.999 ? 105  PHE A CE2 1 
ATOM   640  C  CZ  . PHE A 1 113 ? -8.664  -3.016  43.365  1   15.64  ? 105  PHE A CZ  1 
ATOM   641  N  N   . LYS A 1 114 ? -13.609 2.407   42.713  1   14.296 ? 106  LYS A N   1 
ATOM   642  C  CA  . LYS A 1 114 ? -14.574 3.415   43.136  1   16.363 ? 106  LYS A CA  1 
ATOM   643  C  C   . LYS A 1 114 ? -15.951 2.761   43.094  1   17.663 ? 106  LYS A C   1 
ATOM   644  O  O   . LYS A 1 114 ? -16.34  2.228   42.042  1   17.23  ? 106  LYS A O   1 
ATOM   645  C  CB  . LYS A 1 114 ? -14.4   4.681   42.249  1   17.765 ? 106  LYS A CB  1 
ATOM   646  C  CG  . LYS A 1 114 ? -15.316 5.834   42.712  1   23.359 ? 106  LYS A CG  1 
ATOM   647  C  CD  . LYS A 1 114 ? -14.987 7.074   41.866  1   28.953 ? 106  LYS A CD  1 
ATOM   648  C  CE  . LYS A 1 114 ? -16.078 8.097   42.003  1   39.046 ? 106  LYS A CE  1 
ATOM   649  N  NZ  . LYS A 1 114 ? -15.362 9.37    41.881  1   50.139 ? 106  LYS A NZ  1 
ATOM   650  N  N   . ASP A 1 115 ? -16.661 2.779   44.234  1   18.414 ? 107  ASP A N   1 
ATOM   651  C  CA  . ASP A 1 115 ? -18.036 2.266   44.288  1   20.998 ? 107  ASP A CA  1 
ATOM   652  C  C   . ASP A 1 115 ? -18.143 0.819   43.765  1   19.958 ? 107  ASP A C   1 
ATOM   653  O  O   . ASP A 1 115 ? -19.061 0.471   43.011  1   21.982 ? 107  ASP A O   1 
ATOM   654  C  CB  . ASP A 1 115 ? -18.991 3.205   43.532  1   21.207 ? 107  ASP A CB  1 
ATOM   655  C  CG  . ASP A 1 115 ? -19.035 4.654   44.013  1   29.749 ? 107  ASP A CG  1 
ATOM   656  O  OD1 . ASP A 1 115 ? -18.908 4.872   45.245  1   36.909 ? 107  ASP A OD1 1 
ATOM   657  O  OD2 . ASP A 1 115 ? -19.142 5.54    43.146  1   34.771 ? 107  ASP A OD2 1 
ATOM   658  N  N   . GLY A 1 116 ? -17.174 -0.053  44.092  1   16.218 ? 108  GLY A N   1 
ATOM   659  C  CA  . GLY A 1 116 ? -17.231 -1.453  43.752  1   16.981 ? 108  GLY A CA  1 
ATOM   660  C  C   . GLY A 1 116 ? -16.739 -1.801  42.351  1   17.47  ? 108  GLY A C   1 
ATOM   661  O  O   . GLY A 1 116 ? -16.751 -2.984  42.035  1   19.265 ? 108  GLY A O   1 
ATOM   662  N  N   . LYS A 1 117 ? -16.331 -0.79   41.581  1   16.417 ? 109  LYS A N   1 
ATOM   663  C  CA  . LYS A 1 117 ? -15.912 -1.017  40.196  1   16.88  ? 109  LYS A CA  1 
ATOM   664  C  C   . LYS A 1 117 ? -14.429 -0.692  40.051  1   13.991 ? 109  LYS A C   1 
ATOM   665  O  O   . LYS A 1 117 ? -13.942 0.136   40.784  1   14.904 ? 109  LYS A O   1 
ATOM   666  C  CB  . LYS A 1 117 ? -16.677 -0.111  39.232  1   20.734 ? 109  LYS A CB  1 
ATOM   667  C  CG  . LYS A 1 117 ? -18.197 -0.45   39.207  1   26.092 ? 109  LYS A CG  1 
ATOM   668  C  CD  . LYS A 1 117 ? -18.739 -1.836  38.869  1   24.997 ? 109  LYS A CD  1 
ATOM   669  C  CE  . LYS A 1 117 ? -20.254 -1.716  38.82   1   30.076 ? 109  LYS A CE  1 
ATOM   670  N  NZ  . LYS A 1 117 ? -20.741 -3.083  38.524  1   30.331 ? 109  LYS A NZ  1 
ATOM   671  N  N   . VAL A 1 118 ? -13.737 -1.391  39.155  1   12.814 ? 110  VAL A N   1 
ATOM   672  C  CA  . VAL A 1 118 ? -12.299 -1.271  38.993  1   13.687 ? 110  VAL A CA  1 
ATOM   673  C  C   . VAL A 1 118 ? -12     -0.961  37.535  1   13.118 ? 110  VAL A C   1 
ATOM   674  O  O   . VAL A 1 118 ? -12.49  -1.668  36.654  1   14.095 ? 110  VAL A O   1 
ATOM   675  C  CB  . VAL A 1 118 ? -11.576 -2.561  39.424  1   15.389 ? 110  VAL A CB  1 
ATOM   676  C  CG1 . VAL A 1 118 ? -10.052 -2.305  39.434  1   15.146 ? 110  VAL A CG1 1 
ATOM   677  C  CG2 . VAL A 1 118 ? -12.023 -3.006  40.814  1   17.106 ? 110  VAL A CG2 1 
ATOM   678  N  N   . ASP A 1 119 ? -11.148 0.072   37.271  1   12.368 ? 111  ASP A N   1 
ATOM   679  C  CA  . ASP A 1 119 ? -10.595 0.342   35.936  1   12.153 ? 111  ASP A CA  1 
ATOM   680  C  C   . ASP A 1 119 ? -9.088  0.137   36.017  1   11.917 ? 111  ASP A C   1 
ATOM   681  O  O   . ASP A 1 119 ? -8.466  0.244   37.096  1   12.258 ? 111  ASP A O   1 
ATOM   682  C  CB  . ASP A 1 119 ? -10.911 1.787   35.507  1   12.346 ? 111  ASP A CB  1 
ATOM   683  C  CG  . ASP A 1 119 ? -12.411 2.07    35.403  1   14.164 ? 111  ASP A CG  1 
ATOM   684  O  OD1 . ASP A 1 119 ? -13.134 1.153   35.028  1   13.73  ? 111  ASP A OD1 1 
ATOM   685  O  OD2 . ASP A 1 119 ? -12.835 3.19    35.719  1   17.929 ? 111  ASP A OD2 1 
ATOM   686  N  N   . TYR A 1 120 ? -8.498  -0.123  34.848  1   11.501 ? 112  TYR A N   1 
ATOM   687  C  CA  . TYR A 1 120 ? -7.061  -0.325  34.774  1   10.803 ? 112  TYR A CA  1 
ATOM   688  C  C   . TYR A 1 120 ? -6.445  0.531   33.676  1   12.102 ? 112  TYR A C   1 
ATOM   689  O  O   . TYR A 1 120 ? -7.041  0.679   32.582  1   13.038 ? 112  TYR A O   1 
ATOM   690  C  CB  . TYR A 1 120 ? -6.789  -1.8    34.45   1   11.573 ? 112  TYR A CB  1 
ATOM   691  C  CG  . TYR A 1 120 ? -5.471  -2.185  33.824  1   13.107 ? 112  TYR A CG  1 
ATOM   692  C  CD1 . TYR A 1 120 ? -4.353  -2.378  34.621  1   13.65  ? 112  TYR A CD1 1 
ATOM   693  C  CD2 . TYR A 1 120 ? -5.384  -2.373  32.452  1   15.408 ? 112  TYR A CD2 1 
ATOM   694  C  CE1 . TYR A 1 120 ? -3.157  -2.81   34.04   1   14.844 ? 112  TYR A CE1 1 
ATOM   695  C  CE2 . TYR A 1 120 ? -4.194  -2.812  31.859  1   16.04  ? 112  TYR A CE2 1 
ATOM   696  C  CZ  . TYR A 1 120 ? -3.107  -3.028  32.683  1   16.396 ? 112  TYR A CZ  1 
ATOM   697  O  OH  . TYR A 1 120 ? -1.916  -3.478  32.147  1   20.964 ? 112  TYR A OH  1 
ATOM   698  N  N   . ARG A 1 121 ? -5.261  1.078   33.96   1   11.064 ? 113  ARG A N   1 
ATOM   699  C  CA  . ARG A 1 121 ? -4.45   1.734   32.926  1   12.109 ? 113  ARG A CA  1 
ATOM   700  C  C   . ARG A 1 121 ? -3.013  1.332   33.146  1   12.814 ? 113  ARG A C   1 
ATOM   701  O  O   . ARG A 1 121 ? -2.564  1.261   34.299  1   13.914 ? 113  ARG A O   1 
ATOM   702  C  CB  . ARG A 1 121 ? -4.56   3.268   33.038  1   12.1   ? 113  ARG A CB  1 
ATOM   703  C  CG  . ARG A 1 121 ? -3.706  3.952   31.966  1   11.323 ? 113  ARG A CG  1 
ATOM   704  C  CD  . ARG A 1 121 ? -3.851  5.514   32.097  1   13.626 ? 113  ARG A CD  1 
ATOM   705  N  NE  . ARG A 1 121 ? -5.083  5.975   31.444  1   13.332 ? 113  ARG A NE  1 
ATOM   706  C  CZ  . ARG A 1 121 ? -5.288  6.215   30.145  1   13.76  ? 113  ARG A CZ  1 
ATOM   707  N  NH1 . ARG A 1 121 ? -4.407  5.832   29.235  1   15.438 ? 113  ARG A NH1 1 
ATOM   708  N  NH2 . ARG A 1 121 ? -6.45   6.761   29.799  1   14.878 ? 113  ARG A NH2 1 
ATOM   709  N  N   A GLN A 1 122 ? -2.272  1.045   32.049  0.5 12.127 ? 114  GLN A N   1 
ATOM   710  N  N   B GLN A 1 122 ? -2.295  1.131   32.047  0.5 12.403 ? 114  GLN A N   1 
ATOM   711  C  CA  A GLN A 1 122 ? -0.83   0.715   32.007  0.5 12.442 ? 114  GLN A CA  1 
ATOM   712  C  CA  B GLN A 1 122 ? -0.861  0.933   32.149  0.5 13.335 ? 114  GLN A CA  1 
ATOM   713  C  C   A GLN A 1 122 ? -0.12   1.758   31.132  0.5 12.595 ? 114  GLN A C   1 
ATOM   714  C  C   B GLN A 1 122 ? -0.143  1.824   31.151  0.5 13.078 ? 114  GLN A C   1 
ATOM   715  O  O   A GLN A 1 122 ? -0.619  2.001   30.046  0.5 12.742 ? 114  GLN A O   1 
ATOM   716  O  O   B GLN A 1 122 ? -0.624  1.996   30.044  0.5 13.209 ? 114  GLN A O   1 
ATOM   717  C  CB  A GLN A 1 122 ? -0.644  -0.676  31.372  0.5 11.449 ? 114  GLN A CB  1 
ATOM   718  C  CB  B GLN A 1 122 ? -0.531  -0.534  31.947  0.5 12.378 ? 114  GLN A CB  1 
ATOM   719  C  CG  A GLN A 1 122 ? 0.754   -1.332  31.399  0.5 10.925 ? 114  GLN A CG  1 
ATOM   720  C  CG  B GLN A 1 122 ? 0.973   -0.731  32.006  0.5 12.925 ? 114  GLN A CG  1 
ATOM   721  C  CD  A GLN A 1 122 ? 1.137   -1.836  32.774  0.5 11.546 ? 114  GLN A CD  1 
ATOM   722  C  CD  B GLN A 1 122 ? 1.322   -2.175  32.236  0.5 14.526 ? 114  GLN A CD  1 
ATOM   723  O  OE1 A GLN A 1 122 ? 0.375   -2.575  33.4    0.5 11.58  ? 114  GLN A OE1 1 
ATOM   724  O  OE1 B GLN A 1 122 ? 0.46    -3.052  32.226  0.5 15.477 ? 114  GLN A OE1 1 
ATOM   725  N  NE2 A GLN A 1 122 ? 2.274   -1.412  33.317  0.5 12.473 ? 114  GLN A NE2 1 
ATOM   726  N  NE2 B GLN A 1 122 ? 2.592   -2.432  32.498  0.5 15.974 ? 114  GLN A NE2 1 
ATOM   727  N  N   . ARG A 1 123 ? 0.985   2.4     31.591  1   11.015 ? 115  ARG A N   1 
ATOM   728  C  CA  . ARG A 1 123 ? 1.71    3.269   30.672  1   12.059 ? 115  ARG A CA  1 
ATOM   729  C  C   . ARG A 1 123 ? 3.171   3.362   31.079  1   11.483 ? 115  ARG A C   1 
ATOM   730  O  O   . ARG A 1 123 ? 3.466   3.48    32.269  1   12.266 ? 115  ARG A O   1 
ATOM   731  C  CB  . ARG A 1 123 ? 1.095   4.683   30.736  1   12.662 ? 115  ARG A CB  1 
ATOM   732  C  CG  . ARG A 1 123 ? 1.478   5.542   29.526  1   13.269 ? 115  ARG A CG  1 
ATOM   733  C  CD  . ARG A 1 123 ? 0.626   6.809   29.53   1   14.82  ? 115  ARG A CD  1 
ATOM   734  N  NE  . ARG A 1 123 ? 1.033   7.623   28.385  1   15.969 ? 115  ARG A NE  1 
ATOM   735  C  CZ  . ARG A 1 123 ? 0.249   8.655   27.997  1   18.318 ? 115  ARG A CZ  1 
ATOM   736  N  NH1 . ARG A 1 123 ? -0.827  9.016   28.688  1   17.407 ? 115  ARG A NH1 1 
ATOM   737  N  NH2 . ARG A 1 123 ? 0.54    9.25    26.873  1   17.372 ? 115  ARG A NH2 1 
ATOM   738  N  N   . PHE A 1 124 ? 4.051   3.417   30.06   1   11.286 ? 116  PHE A N   1 
ATOM   739  C  CA  . PHE A 1 124 ? 5.459   3.707   30.342  1   12.115 ? 116  PHE A CA  1 
ATOM   740  C  C   . PHE A 1 124 ? 5.648   5.132   30.852  1   12.175 ? 116  PHE A C   1 
ATOM   741  O  O   . PHE A 1 124 ? 5.05    6.075   30.322  1   13.357 ? 116  PHE A O   1 
ATOM   742  C  CB  . PHE A 1 124 ? 6.314   3.603   29.075  1   11.461 ? 116  PHE A CB  1 
ATOM   743  C  CG  . PHE A 1 124 ? 6.623   2.153   28.73   1   12.701 ? 116  PHE A CG  1 
ATOM   744  C  CD1 . PHE A 1 124 ? 7.509   1.46    29.58   1   12.389 ? 116  PHE A CD1 1 
ATOM   745  C  CD2 . PHE A 1 124 ? 6.07    1.521   27.604  1   11.01  ? 116  PHE A CD2 1 
ATOM   746  C  CE1 . PHE A 1 124 ? 7.773   0.115   29.277  1   12.188 ? 116  PHE A CE1 1 
ATOM   747  C  CE2 . PHE A 1 124 ? 6.379   0.182   27.301  1   12.485 ? 116  PHE A CE2 1 
ATOM   748  C  CZ  . PHE A 1 124 ? 7.238   -0.499  28.138  1   11.598 ? 116  PHE A CZ  1 
ATOM   749  N  N   . VAL A 1 125 ? 6.572   5.284   31.831  1   11.477 ? 117  VAL A N   1 
ATOM   750  C  CA  . VAL A 1 125 ? 7.092   6.615   32.183  1   11.055 ? 117  VAL A CA  1 
ATOM   751  C  C   . VAL A 1 125 ? 7.928   7.148   31.013  1   11.946 ? 117  VAL A C   1 
ATOM   752  O  O   . VAL A 1 125 ? 8.763   6.419   30.472  1   12.204 ? 117  VAL A O   1 
ATOM   753  C  CB  . VAL A 1 125 ? 7.997   6.526   33.439  1   11.82  ? 117  VAL A CB  1 
ATOM   754  C  CG1 . VAL A 1 125 ? 8.356   7.96    33.868  1   13.464 ? 117  VAL A CG1 1 
ATOM   755  C  CG2 . VAL A 1 125 ? 7.317   5.769   34.584  1   11.452 ? 117  VAL A CG2 1 
ATOM   756  N  N   . GLU A 1 126 ? 7.67    8.403   30.583  1   12.509 ? 118  GLU A N   1 
ATOM   757  C  CA  . GLU A 1 126 ? 8.435   8.907   29.443  1   14.019 ? 118  GLU A CA  1 
ATOM   758  C  C   . GLU A 1 126 ? 9.757   9.508   29.922  1   13.658 ? 118  GLU A C   1 
ATOM   759  O  O   . GLU A 1 126 ? 9.974   10.74   29.836  1   14.695 ? 118  GLU A O   1 
ATOM   760  C  CB  . GLU A 1 126 ? 7.697   9.992   28.677  1   16.126 ? 118  GLU A CB  1 
ATOM   761  C  CG  . GLU A 1 126 ? 6.443   9.525   27.978  1   18.803 ? 118  GLU A CG  1 
ATOM   762  C  CD  . GLU A 1 126 ? 5.986   10.729  27.126  1   20.879 ? 118  GLU A CD  1 
ATOM   763  O  OE1 . GLU A 1 126 ? 6.359   11.929  27.279  1   22.437 ? 118  GLU A OE1 1 
ATOM   764  O  OE2 . GLU A 1 126 ? 5.151   10.425  26.323  1   19.274 ? 118  GLU A OE2 1 
ATOM   765  N  N   . THR A 1 127 ? 10.598  8.668   30.53   1   12.585 ? 119  THR A N   1 
ATOM   766  C  CA  . THR A 1 127 ? 11.914  9.146   30.969  1   12.592 ? 119  THR A CA  1 
ATOM   767  C  C   . THR A 1 127 ? 12.695  9.652   29.746  1   12.948 ? 119  THR A C   1 
ATOM   768  O  O   . THR A 1 127 ? 12.42   9.195   28.626  1   12.728 ? 119  THR A O   1 
ATOM   769  C  CB  . THR A 1 127 ? 12.699  8.024   31.646  1   11.555 ? 119  THR A CB  1 
ATOM   770  O  OG1 . THR A 1 127 ? 13.03   7.037   30.671  1   12.495 ? 119  THR A OG1 1 
ATOM   771  C  CG2 . THR A 1 127 ? 11.907  7.374   32.78   1   13.587 ? 119  THR A CG2 1 
ATOM   772  N  N   . ASP A 1 128 ? 13.736  10.466  30.02   1   13.56  ? 120  ASP A N   1 
ATOM   773  C  CA  . ASP A 1 128 ? 14.558  10.898  28.883  1   12.391 ? 120  ASP A CA  1 
ATOM   774  C  C   . ASP A 1 128 ? 15.158  9.714   28.133  1   12.987 ? 120  ASP A C   1 
ATOM   775  O  O   . ASP A 1 128 ? 15.259  9.72    26.896  1   14.026 ? 120  ASP A O   1 
ATOM   776  C  CB  . ASP A 1 128 ? 15.613  11.864  29.358  1   12.6   ? 120  ASP A CB  1 
ATOM   777  C  CG  . ASP A 1 128 ? 15.027  13.221  29.699  1   13.155 ? 120  ASP A CG  1 
ATOM   778  O  OD1 . ASP A 1 128 ? 13.846  13.484  29.276  1   14.478 ? 120  ASP A OD1 1 
ATOM   779  O  OD2 . ASP A 1 128 ? 15.772  13.987  30.363  1   13.52  ? 120  ASP A OD2 1 
ATOM   780  N  N   . ARG A 1 129 ? 15.526  8.662   28.9    1   11.943 ? 121  ARG A N   1 
ATOM   781  C  CA  . ARG A 1 129 ? 16.056  7.438   28.318  1   12.534 ? 121  ARG A CA  1 
ATOM   782  C  C   . ARG A 1 129 ? 15.035  6.732   27.43   1   13.028 ? 121  ARG A C   1 
ATOM   783  O  O   . ARG A 1 129 ? 15.363  6.268   26.341  1   13.16  ? 121  ARG A O   1 
ATOM   784  C  CB  . ARG A 1 129 ? 16.54   6.577   29.501  1   13.123 ? 121  ARG A CB  1 
ATOM   785  C  CG  . ARG A 1 129 ? 16.811  5.109   29.197  1   12.438 ? 121  ARG A CG  1 
ATOM   786  C  CD  . ARG A 1 129 ? 17.681  4.545   30.293  1   11.783 ? 121  ARG A CD  1 
ATOM   787  N  NE  . ARG A 1 129 ? 17.869  3.101   30.133  1   13.463 ? 121  ARG A NE  1 
ATOM   788  C  CZ  . ARG A 1 129 ? 18.691  2.421   30.927  1   13.07  ? 121  ARG A CZ  1 
ATOM   789  N  NH1 . ARG A 1 129 ? 19.404  3.05    31.844  1   14.1   ? 121  ARG A NH1 1 
ATOM   790  N  NH2 . ARG A 1 129 ? 18.757  1.102   30.727  1   14.526 ? 121  ARG A NH2 1 
ATOM   791  N  N   . PHE A 1 130 ? 13.82   6.538   27.971  1   12.244 ? 122  PHE A N   1 
ATOM   792  C  CA  . PHE A 1 130 ? 12.765  5.907   27.18   1   11.742 ? 122  PHE A CA  1 
ATOM   793  C  C   . PHE A 1 130 ? 12.498  6.695   25.895  1   11.925 ? 122  PHE A C   1 
ATOM   794  O  O   . PHE A 1 130 ? 12.316  6.057   24.854  1   13.113 ? 122  PHE A O   1 
ATOM   795  C  CB  . PHE A 1 130 ? 11.498  5.856   28.072  1   12.197 ? 122  PHE A CB  1 
ATOM   796  C  CG  . PHE A 1 130 ? 10.221  5.48    27.337  1   12.372 ? 122  PHE A CG  1 
ATOM   797  C  CD1 . PHE A 1 130 ? 9.425   6.494   26.753  1   12.866 ? 122  PHE A CD1 1 
ATOM   798  C  CD2 . PHE A 1 130 ? 9.86    4.145   27.176  1   12.029 ? 122  PHE A CD2 1 
ATOM   799  C  CE1 . PHE A 1 130 ? 8.256   6.161   26.061  1   13.414 ? 122  PHE A CE1 1 
ATOM   800  C  CE2 . PHE A 1 130 ? 8.646   3.813   26.512  1   13.13  ? 122  PHE A CE2 1 
ATOM   801  C  CZ  . PHE A 1 130 ? 7.856   4.828   25.952  1   13.046 ? 122  PHE A CZ  1 
ATOM   802  N  N   . LYS A 1 131 ? 12.478  8.031   25.983  1   13.282 ? 123  LYS A N   1 
ATOM   803  C  CA  . LYS A 1 131 ? 12.204  8.838   24.791  1   13.55  ? 123  LYS A CA  1 
ATOM   804  C  C   . LYS A 1 131 ? 13.316  8.63    23.757  1   13.546 ? 123  LYS A C   1 
ATOM   805  O  O   . LYS A 1 131 ? 12.984  8.459   22.58   1   13.679 ? 123  LYS A O   1 
ATOM   806  C  CB  . LYS A 1 131 ? 11.993  10.306  25.147  1   14.475 ? 123  LYS A CB  1 
ATOM   807  C  CG  . LYS A 1 131 ? 10.787  10.537  26.103  1   15.158 ? 123  LYS A CG  1 
ATOM   808  C  CD  . LYS A 1 131 ? 10.303  11.99   26.188  1   14.633 ? 123  LYS A CD  1 
ATOM   809  C  CE  . LYS A 1 131 ? 11.328  12.984  26.649  1   14.639 ? 123  LYS A CE  1 
ATOM   810  N  NZ  . LYS A 1 131 ? 12.317  13.447  25.607  1   14.368 ? 123  LYS A NZ  1 
ATOM   811  N  N   . VAL A 1 132 ? 14.581  8.654   24.205  1   13.919 ? 124  VAL A N   1 
ATOM   812  C  CA  . VAL A 1 132 ? 15.69   8.439   23.261  1   14.104 ? 124  VAL A CA  1 
ATOM   813  C  C   . VAL A 1 132 ? 15.479  7.093   22.578  1   13.72  ? 124  VAL A C   1 
ATOM   814  O  O   . VAL A 1 132 ? 15.612  7.002   21.354  1   15.059 ? 124  VAL A O   1 
ATOM   815  C  CB  . VAL A 1 132 ? 17.046  8.475   24.012  1   14.181 ? 124  VAL A CB  1 
ATOM   816  C  CG1 . VAL A 1 132 ? 18.159  7.79    23.201  1   16.713 ? 124  VAL A CG1 1 
ATOM   817  C  CG2 . VAL A 1 132 ? 17.449  9.898   24.367  1   17.062 ? 124  VAL A CG2 1 
ATOM   818  N  N   . GLU A 1 133 ? 15.256  6.028   23.355  1   12.661 ? 125  GLU A N   1 
ATOM   819  C  CA  . GLU A 1 133 ? 15.241  4.71    22.729  1   12.954 ? 125  GLU A CA  1 
ATOM   820  C  C   . GLU A 1 133 ? 14.007  4.476   21.847  1   14.088 ? 125  GLU A C   1 
ATOM   821  O  O   . GLU A 1 133 ? 14.091  3.76    20.838  1   14.992 ? 125  GLU A O   1 
ATOM   822  C  CB  . GLU A 1 133 ? 15.372  3.633   23.801  1   13.84  ? 125  GLU A CB  1 
ATOM   823  C  CG  . GLU A 1 133 ? 16.738  3.707   24.514  1   14.897 ? 125  GLU A CG  1 
ATOM   824  C  CD  . GLU A 1 133 ? 17.031  2.483   25.343  1   16.037 ? 125  GLU A CD  1 
ATOM   825  O  OE1 . GLU A 1 133 ? 16.104  1.746   25.761  1   15.679 ? 125  GLU A OE1 1 
ATOM   826  O  OE2 . GLU A 1 133 ? 18.26   2.243   25.593  1   14.299 ? 125  GLU A OE2 1 
ATOM   827  N  N   . ARG A 1 134 ? 12.848  5.051   22.208  1   14.076 ? 126  ARG A N   1 
ATOM   828  C  CA  . ARG A 1 134 ? 11.66   4.837   21.384  1   13.927 ? 126  ARG A CA  1 
ATOM   829  C  C   . ARG A 1 134 ? 11.806  5.611   20.072  1   14.667 ? 126  ARG A C   1 
ATOM   830  O  O   . ARG A 1 134 ? 11.499  5.064   19.02   1   15.848 ? 126  ARG A O   1 
ATOM   831  C  CB  . ARG A 1 134 ? 10.412  5.324   22.158  1   13.007 ? 126  ARG A CB  1 
ATOM   832  C  CG  . ARG A 1 134 ? 9.183   5.181   21.251  1   13.72  ? 126  ARG A CG  1 
ATOM   833  C  CD  . ARG A 1 134 ? 7.838   5.063   22.041  1   14.076 ? 126  ARG A CD  1 
ATOM   834  N  NE  . ARG A 1 134 ? 7.672   3.739   22.617  1   14.205 ? 126  ARG A NE  1 
ATOM   835  C  CZ  . ARG A 1 134 ? 6.573   3.379   23.258  1   14.602 ? 126  ARG A CZ  1 
ATOM   836  N  NH1 . ARG A 1 134 ? 5.503   4.213   23.349  1   13.944 ? 126  ARG A NH1 1 
ATOM   837  N  NH2 . ARG A 1 134 ? 6.59    2.185   23.812  1   14.25  ? 126  ARG A NH2 1 
ATOM   838  N  N   . ARG A 1 135 ? 12.295  6.847   20.156  1   14.801 ? 127  ARG A N   1 
ATOM   839  C  CA  . ARG A 1 135 ? 12.468  7.689   18.968  1   15.336 ? 127  ARG A CA  1 
ATOM   840  C  C   . ARG A 1 135 ? 13.481  7.051   18.026  1   17.841 ? 127  ARG A C   1 
ATOM   841  O  O   . ARG A 1 135 ? 13.32   7.156   16.813  1   19.62  ? 127  ARG A O   1 
ATOM   842  C  CB  . ARG A 1 135 ? 12.861  9.13    19.285  1   16.843 ? 127  ARG A CB  1 
ATOM   843  C  CG  . ARG A 1 135 ? 11.726  9.863   19.993  1   16.404 ? 127  ARG A CG  1 
ATOM   844  C  CD  . ARG A 1 135 ? 12.08   11.273  20.469  1   17.716 ? 127  ARG A CD  1 
ATOM   845  N  NE  . ARG A 1 135 ? 12.394  12.092  19.294  1   20.377 ? 127  ARG A NE  1 
ATOM   846  C  CZ  . ARG A 1 135 ? 11.49   12.621  18.468  1   21.027 ? 127  ARG A CZ  1 
ATOM   847  N  NH1 . ARG A 1 135 ? 10.208  12.683  18.792  1   18.306 ? 127  ARG A NH1 1 
ATOM   848  N  NH2 . ARG A 1 135 ? 11.925  13.179  17.327  1   24.031 ? 127  ARG A NH2 1 
ATOM   849  N  N   . ALA A 1 136 ? 14.537  6.431   18.567  1   17.255 ? 128  ALA A N   1 
ATOM   850  C  CA  . ALA A 1 136 ? 15.557  5.805   17.723  1   18.196 ? 128  ALA A CA  1 
ATOM   851  C  C   . ALA A 1 136 ? 15.164  4.391   17.342  1   16.963 ? 128  ALA A C   1 
ATOM   852  O  O   . ALA A 1 136 ? 15.852  3.775   16.516  1   19.196 ? 128  ALA A O   1 
ATOM   853  C  CB  . ALA A 1 136 ? 16.875  5.822   18.471  1   17.136 ? 128  ALA A CB  1 
ATOM   854  N  N   . ARG A 1 137 ? 14.104  3.825   17.95   1   16.172 ? 129  ARG A N   1 
ATOM   855  C  CA  . ARG A 1 137 ? 13.77   2.402   17.901  1   15.894 ? 129  ARG A CA  1 
ATOM   856  C  C   . ARG A 1 137 ? 15.033  1.544   18.135  1   17.715 ? 129  ARG A C   1 
ATOM   857  O  O   . ARG A 1 137 ? 15.308  0.545   17.434  1   18.12  ? 129  ARG A O   1 
ATOM   858  C  CB  . ARG A 1 137 ? 13.045  2.037   16.586  1   18.372 ? 129  ARG A CB  1 
ATOM   859  C  CG  . ARG A 1 137 ? 12.442  0.649   16.576  1   20.95  ? 129  ARG A CG  1 
ATOM   860  C  CD  . ARG A 1 137 ? 12.829  0.057   15.198  1   23.959 ? 129  ARG A CD  1 
ATOM   861  N  NE  . ARG A 1 137 ? 12.208  -1.277  15.164  1   23.97  ? 129  ARG A NE  1 
ATOM   862  C  CZ  . ARG A 1 137 ? 12.276  -2.204  14.183  1   24.218 ? 129  ARG A CZ  1 
ATOM   863  N  NH1 . ARG A 1 137 ? 12.963  -1.957  13.071  1   24.127 ? 129  ARG A NH1 1 
ATOM   864  N  NH2 . ARG A 1 137 ? 11.701  -3.394  14.361  1   23.21  ? 129  ARG A NH2 1 
ATOM   865  N  N   . LYS A 1 138 ? 15.782  1.887   19.19   1   15.878 ? 130  LYS A N   1 
ATOM   866  C  CA  . LYS A 1 138 ? 17.094  1.282   19.41   1   17.143 ? 130  LYS A CA  1 
ATOM   867  C  C   . LYS A 1 138 ? 17.484  1.474   20.868  1   15.143 ? 130  LYS A C   1 
ATOM   868  O  O   . LYS A 1 138 ? 17.452  2.576   21.37   1   16.468 ? 130  LYS A O   1 
ATOM   869  C  CB  . LYS A 1 138 ? 18.099  1.946   18.466  1   19.436 ? 130  LYS A CB  1 
ATOM   870  C  CG  . LYS A 1 138 ? 19.44   1.209   18.475  1   23.849 ? 130  LYS A CG  1 
ATOM   871  C  CD  . LYS A 1 138 ? 20.433  1.735   17.44   1   23.178 ? 130  LYS A CD  1 
ATOM   872  C  CE  . LYS A 1 138 ? 21.767  1.007   17.585  1   25.979 ? 130  LYS A CE  1 
ATOM   873  N  NZ  . LYS A 1 138 ? 22.684  1.595   16.594  1   31.814 ? 130  LYS A NZ  1 
ATOM   874  N  N   . SER A 1 139 ? 18.001  0.399   21.461  1   14.556 ? 131  SER A N   1 
ATOM   875  C  CA  . SER A 1 139 ? 18.727  0.484   22.721  1   14.323 ? 131  SER A CA  1 
ATOM   876  C  C   . SER A 1 139 ? 19.982  1.371   22.58   1   15.986 ? 131  SER A C   1 
ATOM   877  O  O   . SER A 1 139 ? 20.786  1.217   21.654  1   16.139 ? 131  SER A O   1 
ATOM   878  C  CB  . SER A 1 139 ? 19.077  -0.917  23.163  1   14.996 ? 131  SER A CB  1 
ATOM   879  O  OG  . SER A 1 139 ? 19.978  -0.923  24.279  1   15.981 ? 131  SER A OG  1 
ATOM   880  N  N   . MET A 1 140 ? 20.172  2.279   23.548  1   14.702 ? 132  MET A N   1 
ATOM   881  C  CA  . MET A 1 140 ? 21.277  3.224   23.546  1   14.354 ? 132  MET A CA  1 
ATOM   882  C  C   . MET A 1 140 ? 21.982  3.262   24.89   1   14.775 ? 132  MET A C   1 
ATOM   883  O  O   . MET A 1 140 ? 22.916  4.038   25.071  1   15.128 ? 132  MET A O   1 
ATOM   884  C  CB  . MET A 1 140 ? 20.83   4.651   23.162  1   15.913 ? 132  MET A CB  1 
ATOM   885  C  CG  . MET A 1 140 ? 20.181  4.736   21.774  1   16.334 ? 132  MET A CG  1 
ATOM   886  S  SD  . MET A 1 140 ? 21.47   4.652   20.51   1   23.17  ? 132  MET A SD  1 
ATOM   887  C  CE  . MET A 1 140 ? 21.933  6.396   20.596  1   20.393 ? 132  MET A CE  1 
ATOM   888  N  N   . TYR A 1 141 ? 21.55   2.388   25.823  1   13.541 ? 133  TYR A N   1 
ATOM   889  C  CA  . TYR A 1 141 ? 22.057  2.41    27.19   1   13.278 ? 133  TYR A CA  1 
ATOM   890  C  C   . TYR A 1 141 ? 22.564  1.029   27.519  1   13.085 ? 133  TYR A C   1 
ATOM   891  O  O   . TYR A 1 141 ? 22.039  0.02    27.032  1   14.086 ? 133  TYR A O   1 
ATOM   892  C  CB  . TYR A 1 141 ? 20.919  2.835   28.145  1   13.575 ? 133  TYR A CB  1 
ATOM   893  C  CG  . TYR A 1 141 ? 20.575  4.306   28.055  1   11.817 ? 133  TYR A CG  1 
ATOM   894  C  CD1 . TYR A 1 141 ? 19.703  4.751   27.047  1   13.814 ? 133  TYR A CD1 1 
ATOM   895  C  CD2 . TYR A 1 141 ? 21.093  5.241   28.935  1   11.641 ? 133  TYR A CD2 1 
ATOM   896  C  CE1 . TYR A 1 141 ? 19.352  6.088   26.945  1   13.363 ? 133  TYR A CE1 1 
ATOM   897  C  CE2 . TYR A 1 141 ? 20.767  6.592   28.83   1   12.839 ? 133  TYR A CE2 1 
ATOM   898  C  CZ  . TYR A 1 141 ? 19.886  7.026   27.829  1   13.912 ? 133  TYR A CZ  1 
ATOM   899  O  OH  . TYR A 1 141 ? 19.483  8.373   27.694  1   15.277 ? 133  TYR A OH  1 
ATOM   900  N  N   . GLY A 1 142 ? 23.618  1.014   28.347  1   13.311 ? 134  GLY A N   1 
ATOM   901  C  CA  . GLY A 1 142 ? 24.307  -0.221  28.725  1   15.543 ? 134  GLY A CA  1 
ATOM   902  C  C   . GLY A 1 142 ? 23.91   -0.731  30.094  1   15.097 ? 134  GLY A C   1 
ATOM   903  O  O   . GLY A 1 142 ? 22.73   -0.91   30.396  1   15.47  ? 134  GLY A O   1 
ATOM   904  N  N   . LEU A 1 143 ? 24.923  -0.905  30.961  1   14.689 ? 135  LEU A N   1 
ATOM   905  C  CA  . LEU A 1 143 ? 24.743  -1.537  32.275  1   14.402 ? 135  LEU A CA  1 
ATOM   906  C  C   . LEU A 1 143 ? 24.051  -0.602  33.252  1   13.323 ? 135  LEU A C   1 
ATOM   907  O  O   . LEU A 1 143 ? 24.142  0.622   33.122  1   14.075 ? 135  LEU A O   1 
ATOM   908  C  CB  . LEU A 1 143 ? 26.077  -1.916  32.931  1   15.136 ? 135  LEU A CB  1 
ATOM   909  C  CG  . LEU A 1 143 ? 26.965  -2.87   32.13   1   14.931 ? 135  LEU A CG  1 
ATOM   910  C  CD1 . LEU A 1 143 ? 28.229  -3.182  32.952  1   16.806 ? 135  LEU A CD1 1 
ATOM   911  C  CD2 . LEU A 1 143 ? 26.261  -4.178  31.799  1   15.762 ? 135  LEU A CD2 1 
ATOM   912  N  N   . TYR A 1 144 ? 23.4    -1.215  34.266  1   13.396 ? 136  TYR A N   1 
ATOM   913  C  CA  . TYR A 1 144 ? 22.815  -0.514  35.391  1   13.763 ? 136  TYR A CA  1 
ATOM   914  C  C   . TYR A 1 144 ? 23.787  0.525   35.942  1   13.612 ? 136  TYR A C   1 
ATOM   915  O  O   . TYR A 1 144 ? 24.886  0.207   36.408  1   14.208 ? 136  TYR A O   1 
ATOM   916  C  CB  . TYR A 1 144 ? 22.431  -1.554  36.464  1   13.617 ? 136  TYR A CB  1 
ATOM   917  C  CG  . TYR A 1 144 ? 21.758  -0.957  37.701  1   13.01  ? 136  TYR A CG  1 
ATOM   918  C  CD1 . TYR A 1 144 ? 20.448  -0.453  37.647  1   13.798 ? 136  TYR A CD1 1 
ATOM   919  C  CD2 . TYR A 1 144 ? 22.442  -0.909  38.933  1   12.814 ? 136  TYR A CD2 1 
ATOM   920  C  CE1 . TYR A 1 144 ? 19.867  0.05    38.809  1   14.493 ? 136  TYR A CE1 1 
ATOM   921  C  CE2 . TYR A 1 144 ? 21.877  -0.357  40.077  1   13.925 ? 136  TYR A CE2 1 
ATOM   922  C  CZ  . TYR A 1 144 ? 20.562  0.087   40.022  1   14.125 ? 136  TYR A CZ  1 
ATOM   923  O  OH  . TYR A 1 144 ? 19.933  0.648   41.106  1   14.736 ? 136  TYR A OH  1 
ATOM   924  N  N   . ARG A 1 145 ? 23.395  1.796   35.9    1   13.638 ? 137  ARG A N   1 
ATOM   925  C  CA  . ARG A 1 145 ? 24.14   2.886   36.518  1   13.696 ? 137  ARG A CA  1 
ATOM   926  C  C   . ARG A 1 145 ? 25.577  2.986   35.983  1   13.572 ? 137  ARG A C   1 
ATOM   927  O  O   . ARG A 1 145 ? 26.46   3.397   36.749  1   13.649 ? 137  ARG A O   1 
ATOM   928  C  CB  . ARG A 1 145 ? 24.115  2.779   38.048  1   12.943 ? 137  ARG A CB  1 
ATOM   929  C  CG  . ARG A 1 145 ? 22.667  2.846   38.556  1   12.103 ? 137  ARG A CG  1 
ATOM   930  C  CD  . ARG A 1 145 ? 22.689  3.046   40.067  1   13.182 ? 137  ARG A CD  1 
ATOM   931  N  NE  . ARG A 1 145 ? 23.211  4.38    40.391  1   13.027 ? 137  ARG A NE  1 
ATOM   932  C  CZ  . ARG A 1 145 ? 22.998  5.007   41.536  1   12.803 ? 137  ARG A CZ  1 
ATOM   933  N  NH1 . ARG A 1 145 ? 22.362  4.389   42.568  1   13.445 ? 137  ARG A NH1 1 
ATOM   934  N  NH2 . ARG A 1 145 ? 23.351  6.279   41.671  1   13.827 ? 137  ARG A NH2 1 
ATOM   935  N  N   . ASN A 1 146 ? 25.822  2.624   34.703  1   13.141 ? 138  ASN A N   1 
ATOM   936  C  CA  . ASN A 1 146 ? 27.193  2.814   34.215  1   14.049 ? 138  ASN A CA  1 
ATOM   937  C  C   . ASN A 1 146 ? 27.171  3.581   32.89   1   12.851 ? 138  ASN A C   1 
ATOM   938  O  O   . ASN A 1 146 ? 27.146  2.986   31.807  1   13.953 ? 138  ASN A O   1 
ATOM   939  C  CB  . ASN A 1 146 ? 27.974  1.501   34.077  1   14.073 ? 138  ASN A CB  1 
ATOM   940  C  CG  . ASN A 1 146 ? 29.413  1.84    33.713  1   12.816 ? 138  ASN A CG  1 
ATOM   941  O  OD1 . ASN A 1 146 ? 29.762  2.997   33.448  1   14.646 ? 138  ASN A OD1 1 
ATOM   942  N  ND2 . ASN A 1 146 ? 30.241  0.822   33.656  1   14.358 ? 138  ASN A ND2 1 
ATOM   943  N  N   . PRO A 1 147 ? 27.183  4.927   32.951  1   13.632 ? 139  PRO A N   1 
ATOM   944  C  CA  . PRO A 1 147 ? 27.236  5.767   31.74   1   12.812 ? 139  PRO A CA  1 
ATOM   945  C  C   . PRO A 1 147 ? 28.397  5.482   30.77   1   14.2   ? 139  PRO A C   1 
ATOM   946  O  O   . PRO A 1 147 ? 28.265  5.779   29.593  1   15.617 ? 139  PRO A O   1 
ATOM   947  C  CB  . PRO A 1 147 ? 27.369  7.14    32.39   1   14.082 ? 139  PRO A CB  1 
ATOM   948  C  CG  . PRO A 1 147 ? 26.502  7.045   33.642  1   14.363 ? 139  PRO A CG  1 
ATOM   949  C  CD  . PRO A 1 147 ? 26.98   5.729   34.177  1   13.596 ? 139  PRO A CD  1 
ATOM   950  N  N   . TYR A 1 148 ? 29.509  4.906   31.263  1   13.812 ? 140  TYR A N   1 
ATOM   951  C  CA  . TYR A 1 148 ? 30.643  4.591   30.367  1   13.271 ? 140  TYR A CA  1 
ATOM   952  C  C   . TYR A 1 148 ? 30.268  3.48    29.404  1   16.047 ? 140  TYR A C   1 
ATOM   953  O  O   . TYR A 1 148 ? 31.021  3.236   28.441  1   17.049 ? 140  TYR A O   1 
ATOM   954  C  CB  . TYR A 1 148 ? 31.883  4.265   31.204  1   13.38  ? 140  TYR A CB  1 
ATOM   955  C  CG  . TYR A 1 148 ? 32.329  5.455   32.03   1   14.125 ? 140  TYR A CG  1 
ATOM   956  C  CD1 . TYR A 1 148 ? 33.015  6.498   31.42   1   15.423 ? 140  TYR A CD1 1 
ATOM   957  C  CD2 . TYR A 1 148 ? 31.967  5.566   33.38   1   15.279 ? 140  TYR A CD2 1 
ATOM   958  C  CE1 . TYR A 1 148 ? 33.353  7.615   32.147  1   15.586 ? 140  TYR A CE1 1 
ATOM   959  C  CE2 . TYR A 1 148 ? 32.299  6.696   34.114  1   14.425 ? 140  TYR A CE2 1 
ATOM   960  C  CZ  . TYR A 1 148 ? 32.994  7.733   33.484  1   15.943 ? 140  TYR A CZ  1 
ATOM   961  O  OH  . TYR A 1 148 ? 33.255  8.848   34.24   1   17.272 ? 140  TYR A OH  1 
ATOM   962  N  N   . THR A 1 149 ? 29.136  2.788   29.637  1   14.14  ? 141  THR A N   1 
ATOM   963  C  CA  . THR A 1 149 ? 28.672  1.737   28.74   1   14.913 ? 141  THR A CA  1 
ATOM   964  C  C   . THR A 1 149 ? 27.447  2.187   27.929  1   15.163 ? 141  THR A C   1 
ATOM   965  O  O   . THR A 1 149 ? 26.966  1.362   27.163  1   16.374 ? 141  THR A O   1 
ATOM   966  C  CB  . THR A 1 149 ? 28.375  0.442   29.516  1   14.408 ? 141  THR A CB  1 
ATOM   967  O  OG1 . THR A 1 149 ? 27.234  0.607   30.384  1   15.171 ? 141  THR A OG1 1 
ATOM   968  C  CG2 . THR A 1 149 ? 29.575  0.017   30.364  1   15.847 ? 141  THR A CG2 1 
ATOM   969  N  N   . HIS A 1 150 ? 27.003  3.448   28.076  1   13.704 ? 142  HIS A N   1 
ATOM   970  C  CA  . HIS A 1 150 ? 25.896  3.933   27.235  1   13.222 ? 142  HIS A CA  1 
ATOM   971  C  C   . HIS A 1 150 ? 26.499  4.456   25.941  1   17.031 ? 142  HIS A C   1 
ATOM   972  O  O   . HIS A 1 150 ? 27.726  4.688   25.873  1   17.314 ? 142  HIS A O   1 
ATOM   973  C  CB  . HIS A 1 150 ? 25.149  5.081   27.919  1   14.831 ? 142  HIS A CB  1 
ATOM   974  C  CG  . HIS A 1 150 ? 24.601  4.713   29.251  1   12.719 ? 142  HIS A CG  1 
ATOM   975  N  ND1 . HIS A 1 150 ? 24.356  3.431   29.694  1   14.344 ? 142  HIS A ND1 1 
ATOM   976  C  CD2 . HIS A 1 150 ? 24.269  5.551   30.254  1   12.151 ? 142  HIS A CD2 1 
ATOM   977  C  CE1 . HIS A 1 150 ? 23.864  3.489   30.919  1   13.045 ? 142  HIS A CE1 1 
ATOM   978  N  NE2 . HIS A 1 150 ? 23.836  4.752   31.311  1   13.838 ? 142  HIS A NE2 1 
ATOM   979  N  N   . HIS A 1 151 ? 25.637  4.659   24.916  1   15.142 ? 143  HIS A N   1 
ATOM   980  C  CA  . HIS A 1 151 ? 26.134  5.231   23.672  1   16.773 ? 143  HIS A CA  1 
ATOM   981  C  C   . HIS A 1 151 ? 26.708  6.621   23.948  1   16.83  ? 143  HIS A C   1 
ATOM   982  O  O   . HIS A 1 151 ? 26.182  7.393   24.76   1   17.245 ? 143  HIS A O   1 
ATOM   983  C  CB  . HIS A 1 151 ? 24.94   5.357   22.716  1   14.724 ? 143  HIS A CB  1 
ATOM   984  C  CG  . HIS A 1 151 ? 25.325  5.789   21.341  1   16.092 ? 143  HIS A CG  1 
ATOM   985  N  ND1 . HIS A 1 151 ? 25.647  7.094   21.054  1   19.207 ? 143  HIS A ND1 1 
ATOM   986  C  CD2 . HIS A 1 151 ? 25.318  5.073   20.212  1   16.917 ? 143  HIS A CD2 1 
ATOM   987  C  CE1 . HIS A 1 151 ? 25.881  7.177   19.745  1   19.415 ? 143  HIS A CE1 1 
ATOM   988  N  NE2 . HIS A 1 151 ? 25.72   5.977   19.224  1   17.898 ? 143  HIS A NE2 1 
ATOM   989  N  N   . PRO A 1 152 ? 27.855  7.029   23.335  1   17.192 ? 144  PRO A N   1 
ATOM   990  C  CA  . PRO A 1 152 ? 28.426  8.351   23.628  1   18.947 ? 144  PRO A CA  1 
ATOM   991  C  C   . PRO A 1 152 ? 27.48   9.534   23.584  1   18.537 ? 144  PRO A C   1 
ATOM   992  O  O   . PRO A 1 152 ? 27.605  10.478  24.375  1   21.344 ? 144  PRO A O   1 
ATOM   993  C  CB  . PRO A 1 152 ? 29.522  8.539   22.528  1   19.655 ? 144  PRO A CB  1 
ATOM   994  C  CG  . PRO A 1 152 ? 29.838  7.118   22.08   1   23.028 ? 144  PRO A CG  1 
ATOM   995  C  CD  . PRO A 1 152 ? 28.655  6.215   22.39   1   18.697 ? 144  PRO A CD  1 
ATOM   996  N  N   . CYS A 1 153 ? 26.476  9.447   22.697  1   17.895 ? 145  CYS A N   1 
ATOM   997  C  CA  . CYS A 1 153 ? 25.578  10.574  22.522  1   20.757 ? 145  CYS A CA  1 
ATOM   998  C  C   . CYS A 1 153 ? 24.6    10.728  23.694  1   20.622 ? 145  CYS A C   1 
ATOM   999  O  O   . CYS A 1 153 ? 24.02   11.791  23.82   1   22.064 ? 145  CYS A O   1 
ATOM   1000 C  CB  . CYS A 1 153 ? 24.808  10.463  21.208  1   24.485 ? 145  CYS A CB  1 
ATOM   1001 S  SG  . CYS A 1 153 ? 25.888  10.956  19.831  1   34.853 ? 145  CYS A SG  1 
ATOM   1002 N  N   . VAL A 1 154 ? 24.468  9.71    24.57   1   16.527 ? 146  VAL A N   1 
ATOM   1003 C  CA  . VAL A 1 154 ? 23.517  9.796   25.672  1   17.919 ? 146  VAL A CA  1 
ATOM   1004 C  C   . VAL A 1 154 ? 24.225  9.731   27.032  1   18.637 ? 146  VAL A C   1 
ATOM   1005 O  O   . VAL A 1 154 ? 23.556  9.651   28.067  1   17.593 ? 146  VAL A O   1 
ATOM   1006 C  CB  . VAL A 1 154 ? 22.408  8.726   25.618  1   17.081 ? 146  VAL A CB  1 
ATOM   1007 C  CG1 . VAL A 1 154 ? 21.658  8.807   24.274  1   22.036 ? 146  VAL A CG1 1 
ATOM   1008 C  CG2 . VAL A 1 154 ? 22.911  7.295   25.892  1   19.006 ? 146  VAL A CG2 1 
ATOM   1009 N  N   . ARG A 1 155 ? 25.58   9.739   27.056  1   18.622 ? 147  ARG A N   1 
ATOM   1010 C  CA  . ARG A 1 155 ? 26.253  9.511   28.333  1   18.946 ? 147  ARG A CA  1 
ATOM   1011 C  C   . ARG A 1 155 ? 25.904  10.604  29.336  1   18.915 ? 147  ARG A C   1 
ATOM   1012 O  O   . ARG A 1 155 ? 25.914  10.32   30.538  1   19.411 ? 147  ARG A O   1 
ATOM   1013 C  CB  . ARG A 1 155 ? 27.775  9.571   28.139  1   20.092 ? 147  ARG A CB  1 
ATOM   1014 C  CG  . ARG A 1 155 ? 28.132  8.234   27.529  1   22.201 ? 147  ARG A CG  1 
ATOM   1015 C  CD  . ARG A 1 155 ? 29.666  7.942   27.647  1   20.209 ? 147  ARG A CD  1 
ATOM   1016 N  NE  . ARG A 1 155 ? 29.774  6.678   26.922  1   25.652 ? 147  ARG A NE  1 
ATOM   1017 C  CZ  . ARG A 1 155 ? 30.814  6.318   26.205  1   29.755 ? 147  ARG A CZ  1 
ATOM   1018 N  NH1 . ARG A 1 155 ? 31.887  7.106   26.183  1   31.304 ? 147  ARG A NH1 1 
ATOM   1019 N  NH2 . ARG A 1 155 ? 30.745  5.195   25.522  1   28.928 ? 147  ARG A NH2 1 
ATOM   1020 N  N   . GLN A 1 156 ? 25.638  11.836  28.871  1   18.485 ? 148  GLN A N   1 
ATOM   1021 C  CA  . GLN A 1 156 ? 25.365  12.929  29.781  1   17.333 ? 148  GLN A CA  1 
ATOM   1022 C  C   . GLN A 1 156 ? 23.869  13.206  29.887  1   20.557 ? 148  GLN A C   1 
ATOM   1023 O  O   . GLN A 1 156 ? 23.469  14.323  30.193  1   20.516 ? 148  GLN A O   1 
ATOM   1024 C  CB  . GLN A 1 156 ? 26.211  14.134  29.355  1   25.274 ? 148  GLN A CB  1 
ATOM   1025 C  CG  . GLN A 1 156 ? 26.657  14.982  30.539  1   26.301 ? 148  GLN A CG  1 
ATOM   1026 C  CD  . GLN A 1 156 ? 27.606  16.107  30.14   1   31.785 ? 148  GLN A CD  1 
ATOM   1027 O  OE1 . GLN A 1 156 ? 27.709  17.114  30.838  1   38.341 ? 148  GLN A OE1 1 
ATOM   1028 N  NE2 . GLN A 1 156 ? 28.284  15.96   29.011  1   38.32  ? 148  GLN A NE2 1 
ATOM   1029 N  N   . THR A 1 157 ? 23.031  12.164  29.769  1   18.431 ? 149  THR A N   1 
ATOM   1030 C  CA  . THR A 1 157 ? 21.589  12.268  29.992  1   15.668 ? 149  THR A CA  1 
ATOM   1031 C  C   . THR A 1 157 ? 21.298  11.739  31.386  1   14.37  ? 149  THR A C   1 
ATOM   1032 O  O   . THR A 1 157 ? 22.156  11.115  32.029  1   15.093 ? 149  THR A O   1 
ATOM   1033 C  CB  . THR A 1 157 ? 20.773  11.45   28.985  1   15.729 ? 149  THR A CB  1 
ATOM   1034 O  OG1 . THR A 1 157 ? 21.124  10.063  29.053  1   15.797 ? 149  THR A OG1 1 
ATOM   1035 C  CG2 . THR A 1 157 ? 20.953  11.965  27.57   1   17.28  ? 149  THR A CG2 1 
ATOM   1036 N  N   . VAL A 1 158 ? 20.069  12.035  31.862  1   12.243 ? 150  VAL A N   1 
ATOM   1037 C  CA  . VAL A 1 158 ? 19.526  11.292  33.019  1   12.594 ? 150  VAL A CA  1 
ATOM   1038 C  C   . VAL A 1 158 ? 19.244  9.881   32.528  1   12.391 ? 150  VAL A C   1 
ATOM   1039 O  O   . VAL A 1 158 ? 18.458  9.68    31.609  1   13.429 ? 150  VAL A O   1 
ATOM   1040 C  CB  . VAL A 1 158 ? 18.305  12.055  33.563  1   14.175 ? 150  VAL A CB  1 
ATOM   1041 C  CG1 . VAL A 1 158 ? 17.515  11.176  34.534  1   14.565 ? 150  VAL A CG1 1 
ATOM   1042 C  CG2 . VAL A 1 158 ? 18.82   13.309  34.261  1   16.484 ? 150  VAL A CG2 1 
ATOM   1043 N  N   . GLU A 1 159 ? 19.897  8.894   33.176  1   12.185 ? 151  GLU A N   1 
ATOM   1044 C  CA  . GLU A 1 159 ? 19.842  7.5     32.752  1   12.686 ? 151  GLU A CA  1 
ATOM   1045 C  C   . GLU A 1 159 ? 18.759  6.718   33.511  1   11.133 ? 151  GLU A C   1 
ATOM   1046 O  O   . GLU A 1 159 ? 18.557  5.546   33.208  1   12.739 ? 151  GLU A O   1 
ATOM   1047 C  CB  . GLU A 1 159 ? 21.191  6.762   32.889  1   13.512 ? 151  GLU A CB  1 
ATOM   1048 C  CG  . GLU A 1 159 ? 21.735  6.917   34.324  1   13.838 ? 151  GLU A CG  1 
ATOM   1049 C  CD  . GLU A 1 159 ? 22.652  5.807   34.808  1   14.76  ? 151  GLU A CD  1 
ATOM   1050 O  OE1 . GLU A 1 159 ? 23.09   4.978   33.983  1   14.903 ? 151  GLU A OE1 1 
ATOM   1051 O  OE2 . GLU A 1 159 ? 22.768  5.726   36.066  1   15.742 ? 151  GLU A OE2 1 
ATOM   1052 N  N   . SER A 1 160 ? 18.068  7.355   34.457  1   10.932 ? 152  SER A N   1 
ATOM   1053 C  CA  . SER A 1 160 ? 17.044  6.662   35.254  1   10.551 ? 152  SER A CA  1 
ATOM   1054 C  C   . SER A 1 160 ? 15.93   6.124   34.359  1   11.654 ? 152  SER A C   1 
ATOM   1055 O  O   . SER A 1 160 ? 15.399  6.819   33.469  1   13.038 ? 152  SER A O   1 
ATOM   1056 C  CB  . SER A 1 160 ? 16.399  7.667   36.157  1   11.678 ? 152  SER A CB  1 
ATOM   1057 O  OG  . SER A 1 160 ? 15.225  7.13    36.782  1   11.929 ? 152  SER A OG  1 
ATOM   1058 N  N   . THR A 1 161 ? 15.531  4.888   34.671  1   10.834 ? 153  THR A N   1 
ATOM   1059 C  CA  . THR A 1 161 ? 14.345  4.298   34.06   1   11.301 ? 153  THR A CA  1 
ATOM   1060 C  C   . THR A 1 161 ? 13.11   4.397   34.951  1   10.803 ? 153  THR A C   1 
ATOM   1061 O  O   . THR A 1 161 ? 12.058  3.87    34.582  1   11.595 ? 153  THR A O   1 
ATOM   1062 C  CB  . THR A 1 161 ? 14.61   2.824   33.718  1   11.697 ? 153  THR A CB  1 
ATOM   1063 O  OG1 . THR A 1 161 ? 15.086  2.153   34.896  1   11.261 ? 153  THR A OG1 1 
ATOM   1064 C  CG2 . THR A 1 161 ? 15.613  2.667   32.583  1   12.436 ? 153  THR A CG2 1 
ATOM   1065 N  N   . ALA A 1 162 ? 13.221  5.106   36.098  1   11.283 ? 154  ALA A N   1 
ATOM   1066 C  CA  . ALA A 1 162 ? 12.042  5.47    36.897  1   11.231 ? 154  ALA A CA  1 
ATOM   1067 C  C   . ALA A 1 162 ? 11.109  4.278   37.092  1   12.523 ? 154  ALA A C   1 
ATOM   1068 O  O   . ALA A 1 162 ? 9.916   4.345   36.78   1   12.739 ? 154  ALA A O   1 
ATOM   1069 C  CB  . ALA A 1 162 ? 11.35   6.692   36.27   1   11.2   ? 154  ALA A CB  1 
ATOM   1070 N  N   . ASN A 1 163 ? 11.685  3.19    37.66   1   11.416 ? 155  ASN A N   1 
ATOM   1071 C  CA  . ASN A 1 163 ? 10.999  1.897   37.565  1   11.879 ? 155  ASN A CA  1 
ATOM   1072 C  C   . ASN A 1 163 ? 10.832  1.218   38.913  1   12.414 ? 155  ASN A C   1 
ATOM   1073 O  O   . ASN A 1 163 ? 10.49   0.032   38.906  1   12.41  ? 155  ASN A O   1 
ATOM   1074 C  CB  . ASN A 1 163 ? 11.725  0.948   36.59   1   10.366 ? 155  ASN A CB  1 
ATOM   1075 C  CG  . ASN A 1 163 ? 13.079  0.538   37.093  1   11.249 ? 155  ASN A CG  1 
ATOM   1076 O  OD1 . ASN A 1 163 ? 13.55   1.061   38.109  1   12.759 ? 155  ASN A OD1 1 
ATOM   1077 N  ND2 . ASN A 1 163 ? 13.693  -0.423  36.422  1   12.262 ? 155  ASN A ND2 1 
ATOM   1078 N  N   . THR A 1 164 ? 11.048  1.911   40.065  1   11.194 ? 156  THR A N   1 
ATOM   1079 C  CA  . THR A 1 164 ? 11.031  1.103   41.297  1   11.572 ? 156  THR A CA  1 
ATOM   1080 C  C   . THR A 1 164 ? 9.89    1.407   42.248  1   12.448 ? 156  THR A C   1 
ATOM   1081 O  O   . THR A 1 164 ? 9.457   0.483   42.936  1   12.166 ? 156  THR A O   1 
ATOM   1082 C  CB  . THR A 1 164 ? 12.408  1.171   41.946  1   18.292 ? 156  THR A CB  1 
ATOM   1083 O  OG1 . THR A 1 164 ? 13.498  0.676   41.162  1   22.77  ? 156  THR A OG1 1 
ATOM   1084 C  CG2 . THR A 1 164 ? 12.523  0.615   43.332  1   24.332 ? 156  THR A CG2 1 
ATOM   1085 N  N   . ASN A 1 165 ? 9.47    2.666   42.417  1   10.871 ? 157  ASN A N   1 
ATOM   1086 C  CA  . ASN A 1 165 ? 8.379   2.941   43.366  1   10.969 ? 157  ASN A CA  1 
ATOM   1087 C  C   . ASN A 1 165 ? 7.689   4.242   42.955  1   11.729 ? 157  ASN A C   1 
ATOM   1088 O  O   . ASN A 1 165 ? 8.153   4.959   42.072  1   11.372 ? 157  ASN A O   1 
ATOM   1089 C  CB  . ASN A 1 165 ? 8.966   3       44.782  1   11.857 ? 157  ASN A CB  1 
ATOM   1090 C  CG  . ASN A 1 165 ? 7.96    3.058   45.902  1   11.286 ? 157  ASN A CG  1 
ATOM   1091 O  OD1 . ASN A 1 165 ? 6.801   2.659   45.731  1   12.537 ? 157  ASN A OD1 1 
ATOM   1092 N  ND2 . ASN A 1 165 ? 8.421   3.52    47.056  1   11.57  ? 157  ASN A ND2 1 
ATOM   1093 N  N   . VAL A 1 166 ? 6.527   4.493   43.556  1   11.292 ? 158  VAL A N   1 
ATOM   1094 C  CA  . VAL A 1 166 ? 5.717   5.673   43.26   1   11.895 ? 158  VAL A CA  1 
ATOM   1095 C  C   . VAL A 1 166 ? 5.282   6.298   44.579  1   11.378 ? 158  VAL A C   1 
ATOM   1096 O  O   . VAL A 1 166 ? 5.304   5.655   45.627  1   11.726 ? 158  VAL A O   1 
ATOM   1097 C  CB  . VAL A 1 166 ? 4.472   5.322   42.421  1   10.866 ? 158  VAL A CB  1 
ATOM   1098 C  CG1 . VAL A 1 166 ? 4.856   4.733   41.055  1   11.606 ? 158  VAL A CG1 1 
ATOM   1099 C  CG2 . VAL A 1 166 ? 3.523   4.383   43.18   1   12.291 ? 158  VAL A CG2 1 
ATOM   1100 N  N   . VAL A 1 167 ? 4.899   7.597   44.501  1   11.295 ? 159  VAL A N   1 
ATOM   1101 C  CA  . VAL A 1 167 ? 4.393   8.306   45.692  1   11.942 ? 159  VAL A CA  1 
ATOM   1102 C  C   . VAL A 1 167 ? 3.453   9.416   45.193  1   12.484 ? 159  VAL A C   1 
ATOM   1103 O  O   . VAL A 1 167 ? 3.671   9.964   44.101  1   12.854 ? 159  VAL A O   1 
ATOM   1104 C  CB  . VAL A 1 167 ? 5.52    8.85    46.602  1   11.56  ? 159  VAL A CB  1 
ATOM   1105 C  CG1 . VAL A 1 167 ? 6.349   9.935   45.901  1   13.545 ? 159  VAL A CG1 1 
ATOM   1106 C  CG2 . VAL A 1 167 ? 5.034   9.35    47.97   1   12.774 ? 159  VAL A CG2 1 
ATOM   1107 N  N   . MET A 1 168 ? 2.429   9.751   45.984  1   10.809 ? 160  MET A N   1 
ATOM   1108 C  CA  . MET A 1 168 ? 1.611   10.941  45.77   1   11.907 ? 160  MET A CA  1 
ATOM   1109 C  C   . MET A 1 168 ? 1.931   11.879  46.922  1   12.989 ? 160  MET A C   1 
ATOM   1110 O  O   . MET A 1 168 ? 1.652   11.533  48.064  1   13.204 ? 160  MET A O   1 
ATOM   1111 C  CB  . MET A 1 168 ? 0.128   10.556  45.841  1   12.637 ? 160  MET A CB  1 
ATOM   1112 C  CG  . MET A 1 168 ? -0.857  11.746  45.663  1   13.928 ? 160  MET A CG  1 
ATOM   1113 S  SD  . MET A 1 168 ? -0.838  12.507  44.015  1   16.428 ? 160  MET A SD  1 
ATOM   1114 C  CE  . MET A 1 168 ? -1.776  11.286  43.152  1   16.848 ? 160  MET A CE  1 
ATOM   1115 N  N   . HIS A 1 169 ? 2.534   13.036  46.602  1   12.687 ? 161  HIS A N   1 
ATOM   1116 C  CA  . HIS A 1 169 ? 2.944   13.937  47.671  1   13.252 ? 161  HIS A CA  1 
ATOM   1117 C  C   . HIS A 1 169 ? 2.595   15.346  47.184  1   12.973 ? 161  HIS A C   1 
ATOM   1118 O  O   . HIS A 1 169 ? 2.966   15.71   46.076  1   13.93  ? 161  HIS A O   1 
ATOM   1119 C  CB  . HIS A 1 169 ? 4.458   13.841  47.954  1   12.78  ? 161  HIS A CB  1 
ATOM   1120 C  CG  . HIS A 1 169 ? 4.77    14.691  49.133  1   14.551 ? 161  HIS A CG  1 
ATOM   1121 N  ND1 . HIS A 1 169 ? 4.377   14.4    50.42   1   12.908 ? 161  HIS A ND1 1 
ATOM   1122 C  CD2 . HIS A 1 169 ? 5.363   15.934  49.161  1   14.485 ? 161  HIS A CD2 1 
ATOM   1123 C  CE1 . HIS A 1 169 ? 4.732   15.396  51.215  1   13.78  ? 161  HIS A CE1 1 
ATOM   1124 N  NE2 . HIS A 1 169 ? 5.302   16.353  50.472  1   13.183 ? 161  HIS A NE2 1 
ATOM   1125 N  N   . ALA A 1 170 ? 1.963   16.14   48.084  1   13.918 ? 162  ALA A N   1 
ATOM   1126 C  CA  . ALA A 1 170 ? 1.667   17.543  47.744  1   15.171 ? 162  ALA A CA  1 
ATOM   1127 C  C   . ALA A 1 170 ? 0.928   17.669  46.409  1   14.759 ? 162  ALA A C   1 
ATOM   1128 O  O   . ALA A 1 170 ? 1.114   18.587  45.615  1   16.037 ? 162  ALA A O   1 
ATOM   1129 C  CB  . ALA A 1 170 ? 2.923   18.405  47.805  1   15.467 ? 162  ALA A CB  1 
ATOM   1130 N  N   . GLY A 1 171 ? 0.028   16.714  46.165  1   13.691 ? 163  GLY A N   1 
ATOM   1131 C  CA  . GLY A 1 171 ? -0.794  16.755  44.966  1   13.501 ? 163  GLY A CA  1 
ATOM   1132 C  C   . GLY A 1 171 ? -0.087  16.284  43.697  1   11.936 ? 163  GLY A C   1 
ATOM   1133 O  O   . GLY A 1 171 ? -0.614  16.536  42.621  1   14.224 ? 163  GLY A O   1 
ATOM   1134 N  N   . ARG A 1 172 ? 1.147   15.808  43.819  1   13.462 ? 164  ARG A N   1 
ATOM   1135 C  CA  . ARG A 1 172 ? 1.957   15.426  42.663  1   13.456 ? 164  ARG A CA  1 
ATOM   1136 C  C   . ARG A 1 172 ? 2.255   13.904  42.734  1   11.407 ? 164  ARG A C   1 
ATOM   1137 O  O   . ARG A 1 172 ? 2.68    13.369  43.769  1   12.166 ? 164  ARG A O   1 
ATOM   1138 C  CB  . ARG A 1 172 ? 3.315   16.147  42.656  1   16.124 ? 164  ARG A CB  1 
ATOM   1139 C  CG  . ARG A 1 172 ? 3.265   17.61   43.076  1   21.858 ? 164  ARG A CG  1 
ATOM   1140 C  CD  . ARG A 1 172 ? 2.691   18.456  42.024  1   24.7   ? 164  ARG A CD  1 
ATOM   1141 N  NE  . ARG A 1 172 ? 3.703   18.769  40.997  1   27.787 ? 164  ARG A NE  1 
ATOM   1142 C  CZ  . ARG A 1 172 ? 4.473   19.814  40.798  1   27.898 ? 164  ARG A CZ  1 
ATOM   1143 N  NH1 . ARG A 1 172 ? 4.77    20.663  41.772  1   30.333 ? 164  ARG A NH1 1 
ATOM   1144 N  NH2 . ARG A 1 172 ? 4.986   19.964  39.595  1   23.547 ? 164  ARG A NH2 1 
ATOM   1145 N  N   . PHE A 1 173 ? 2.082   13.248  41.605  1   12.04  ? 165  PHE A N   1 
ATOM   1146 C  CA  . PHE A 1 173 ? 2.315   11.808  41.466  1   11.354 ? 165  PHE A CA  1 
ATOM   1147 C  C   . PHE A 1 173 ? 3.674   11.556  40.822  1   11.237 ? 165  PHE A C   1 
ATOM   1148 O  O   . PHE A 1 173 ? 3.904   12.011  39.696  1   12.214 ? 165  PHE A O   1 
ATOM   1149 C  CB  . PHE A 1 173 ? 1.159   11.152  40.697  1   12.332 ? 165  PHE A CB  1 
ATOM   1150 C  CG  . PHE A 1 173 ? 1.312   9.639   40.604  1   13.155 ? 165  PHE A CG  1 
ATOM   1151 C  CD1 . PHE A 1 173 ? 1.181   8.826   41.731  1   13.389 ? 165  PHE A CD1 1 
ATOM   1152 C  CD2 . PHE A 1 173 ? 1.559   9.05    39.375  1   14.976 ? 165  PHE A CD2 1 
ATOM   1153 C  CE1 . PHE A 1 173 ? 1.336   7.444   41.605  1   15.102 ? 165  PHE A CE1 1 
ATOM   1154 C  CE2 . PHE A 1 173 ? 1.717   7.65    39.258  1   17.297 ? 165  PHE A CE2 1 
ATOM   1155 C  CZ  . PHE A 1 173 ? 1.582   6.856   40.392  1   14.811 ? 165  PHE A CZ  1 
ATOM   1156 N  N   . LEU A 1 174 ? 4.545   10.842  41.553  1   12.116 ? 166  LEU A N   1 
ATOM   1157 C  CA  . LEU A 1 174 ? 5.957   10.643  41.137  1   11.972 ? 166  LEU A CA  1 
ATOM   1158 C  C   . LEU A 1 174 ? 6.268   9.162   40.877  1   11.841 ? 166  LEU A C   1 
ATOM   1159 O  O   . LEU A 1 174 ? 5.889   8.294   41.673  1   12.857 ? 166  LEU A O   1 
ATOM   1160 C  CB  . LEU A 1 174 ? 6.871   11.118  42.267  1   13.058 ? 166  LEU A CB  1 
ATOM   1161 C  CG  . LEU A 1 174 ? 7.218   12.621  42.356  1   16.123 ? 166  LEU A CG  1 
ATOM   1162 C  CD1 . LEU A 1 174 ? 5.985   13.53   42.458  1   18.47  ? 166  LEU A CD1 1 
ATOM   1163 C  CD2 . LEU A 1 174 ? 8.083   12.868  43.591  1   16.834 ? 166  LEU A CD2 1 
ATOM   1164 N  N   . ALA A 1 175 ? 7.043   8.915   39.814  1   11.52  ? 167  ALA A N   1 
ATOM   1165 C  CA  . ALA A 1 175 ? 7.72    7.653   39.557  1   11.149 ? 167  ALA A CA  1 
ATOM   1166 C  C   . ALA A 1 175 ? 9.182   7.856   39.935  1   11.522 ? 167  ALA A C   1 
ATOM   1167 O  O   . ALA A 1 175 ? 9.791   8.824   39.472  1   12.388 ? 167  ALA A O   1 
ATOM   1168 C  CB  . ALA A 1 175 ? 7.564   7.254   38.085  1   12.038 ? 167  ALA A CB  1 
ATOM   1169 N  N   . MET A 1 176 ? 9.75    6.919   40.698  1   11.029 ? 168  MET A N   1 
ATOM   1170 C  CA  . MET A 1 176 ? 11.069  7.104   41.288  1   11.243 ? 168  MET A CA  1 
ATOM   1171 C  C   . MET A 1 176 ? 12.006  5.962   40.932  1   12.135 ? 168  MET A C   1 
ATOM   1172 O  O   . MET A 1 176 ? 11.59   4.805   40.79   1   12.377 ? 168  MET A O   1 
ATOM   1173 C  CB  . MET A 1 176 ? 10.879  7.132   42.805  1   12.892 ? 168  MET A CB  1 
ATOM   1174 C  CG  . MET A 1 176 ? 10.037  8.292   43.286  1   13.165 ? 168  MET A CG  1 
ATOM   1175 S  SD  . MET A 1 176 ? 9.76    8.324   45.078  1   13.157 ? 168  MET A SD  1 
ATOM   1176 C  CE  . MET A 1 176 ? 8.674   6.894   45.318  1   14.768 ? 168  MET A CE  1 
ATOM   1177 N  N   . LYS A 1 177 ? 13.302  6.308   40.932  1   11.378 ? 169  LYS A N   1 
ATOM   1178 C  CA  . LYS A 1 177 ? 14.402  5.367   40.868  1   12.434 ? 169  LYS A CA  1 
ATOM   1179 C  C   . LYS A 1 177 ? 15.617  6.113   41.443  1   12.565 ? 169  LYS A C   1 
ATOM   1180 O  O   . LYS A 1 177 ? 15.827  7.284   41.127  1   12.112 ? 169  LYS A O   1 
ATOM   1181 C  CB  . LYS A 1 177 ? 14.652  4.897   39.43   1   13.399 ? 169  LYS A CB  1 
ATOM   1182 C  CG  . LYS A 1 177 ? 15.676  3.743   39.384  1   12.89  ? 169  LYS A CG  1 
ATOM   1183 C  CD  . LYS A 1 177 ? 15.989  3.326   37.943  1   12.199 ? 169  LYS A CD  1 
ATOM   1184 C  CE  . LYS A 1 177 ? 16.879  2.103   37.816  1   13.58  ? 169  LYS A CE  1 
ATOM   1185 N  NZ  . LYS A 1 177 ? 16.277  0.928   38.48   1   12.83  ? 169  LYS A NZ  1 
ATOM   1186 N  N   . GLU A 1 178 ? 16.409  5.41    42.27   1   12.009 ? 170  GLU A N   1 
ATOM   1187 C  CA  . GLU A 1 178 ? 17.375  6.079   43.138  1   11.172 ? 170  GLU A CA  1 
ATOM   1188 C  C   . GLU A 1 178 ? 18.595  6.706   42.442  1   11.544 ? 170  GLU A C   1 
ATOM   1189 O  O   . GLU A 1 178 ? 19.348  7.399   43.139  1   11.919 ? 170  GLU A O   1 
ATOM   1190 C  CB  . GLU A 1 178 ? 17.801  5.101   44.223  1   11.787 ? 170  GLU A CB  1 
ATOM   1191 C  CG  . GLU A 1 178 ? 18.671  3.93    43.709  1   12.216 ? 170  GLU A CG  1 
ATOM   1192 C  CD  . GLU A 1 178 ? 18.554  2.782   44.723  1   13.712 ? 170  GLU A CD  1 
ATOM   1193 O  OE1 . GLU A 1 178 ? 17.466  2.19    44.725  1   17.771 ? 170  GLU A OE1 1 
ATOM   1194 O  OE2 . GLU A 1 178 ? 19.395  2.618   45.588  1   14.57  ? 170  GLU A OE2 1 
ATOM   1195 N  N   . ASN A 1 179 ? 18.748  6.495   41.131  1   10.547 ? 171  ASN A N   1 
ATOM   1196 C  CA  . ASN A 1 179 ? 19.869  7.082   40.369  1   11.285 ? 171  ASN A CA  1 
ATOM   1197 C  C   . ASN A 1 179 ? 19.475  8.368   39.67   1   12.428 ? 171  ASN A C   1 
ATOM   1198 O  O   . ASN A 1 179 ? 20.273  8.872   38.883  1   12.719 ? 171  ASN A O   1 
ATOM   1199 C  CB  . ASN A 1 179 ? 20.504  6.087   39.399  1   11.101 ? 171  ASN A CB  1 
ATOM   1200 C  CG  . ASN A 1 179 ? 19.521  5.61    38.352  1   11.692 ? 171  ASN A CG  1 
ATOM   1201 O  OD1 . ASN A 1 179 ? 18.298  5.581   38.573  1   12.352 ? 171  ASN A OD1 1 
ATOM   1202 N  ND2 . ASN A 1 179 ? 20.003  5.17    37.203  1   13.152 ? 171  ASN A ND2 1 
ATOM   1203 N  N   . GLY A 1 180 ? 18.334  8.954   40.037  1   11.735 ? 172  GLY A N   1 
ATOM   1204 C  CA  . GLY A 1 180 ? 17.939  10.23   39.464  1   11.885 ? 172  GLY A CA  1 
ATOM   1205 C  C   . GLY A 1 180 ? 16.864  10.87   40.349  1   11.137 ? 172  GLY A C   1 
ATOM   1206 O  O   . GLY A 1 180 ? 16.347  10.236  41.268  1   12.361 ? 172  GLY A O   1 
ATOM   1207 N  N   . ASN A 1 181 ? 16.515  12.136  40.054  1   11.689 ? 173  ASN A N   1 
ATOM   1208 C  CA  . ASN A 1 181 ? 15.288  12.651  40.641  1   11.413 ? 173  ASN A CA  1 
ATOM   1209 C  C   . ASN A 1 181 ? 14.074  12.002  39.987  1   10.38  ? 173  ASN A C   1 
ATOM   1210 O  O   . ASN A 1 181 ? 14.183  11.265  38.998  1   12.124 ? 173  ASN A O   1 
ATOM   1211 C  CB  . ASN A 1 181 ? 15.276  14.183  40.531  1   11.971 ? 173  ASN A CB  1 
ATOM   1212 C  CG  . ASN A 1 181 ? 16.006  14.773  41.713  1   12.435 ? 173  ASN A CG  1 
ATOM   1213 O  OD1 . ASN A 1 181 ? 15.527  14.695  42.858  1   13.683 ? 173  ASN A OD1 1 
ATOM   1214 N  ND2 . ASN A 1 181 ? 17.204  15.327  41.487  1   12.978 ? 173  ASN A ND2 1 
ATOM   1215 N  N   . ALA A 1 182 ? 12.908  12.202  40.618  1   12.185 ? 174  ALA A N   1 
ATOM   1216 C  CA  . ALA A 1 182 ? 11.681  11.571  40.124  1   12.103 ? 174  ALA A CA  1 
ATOM   1217 C  C   . ALA A 1 182 ? 11.163  12.204  38.841  1   13.215 ? 174  ALA A C   1 
ATOM   1218 O  O   . ALA A 1 182 ? 11.391  13.393  38.584  1   13.99  ? 174  ALA A O   1 
ATOM   1219 C  CB  . ALA A 1 182 ? 10.618  11.662  41.19   1   13.404 ? 174  ALA A CB  1 
ATOM   1220 N  N   . TYR A 1 183 ? 10.341  11.431  38.114  1   11.953 ? 175  TYR A N   1 
ATOM   1221 C  CA  . TYR A 1 183 ? 9.517   11.966  37.034  1   11.631 ? 175  TYR A CA  1 
ATOM   1222 C  C   . TYR A 1 183 ? 8.089   12.1    37.54   1   13.035 ? 175  TYR A C   1 
ATOM   1223 O  O   . TYR A 1 183 ? 7.56    11.181  38.181  1   13.575 ? 175  TYR A O   1 
ATOM   1224 C  CB  . TYR A 1 183 ? 9.56    11.035  35.816  1   11.663 ? 175  TYR A CB  1 
ATOM   1225 C  CG  . TYR A 1 183 ? 10.877  11.111  35.036  1   11.35  ? 175  TYR A CG  1 
ATOM   1226 C  CD1 . TYR A 1 183 ? 11.991  10.334  35.414  1   12.409 ? 175  TYR A CD1 1 
ATOM   1227 C  CD2 . TYR A 1 183 ? 11.003  11.979  33.954  1   12.704 ? 175  TYR A CD2 1 
ATOM   1228 C  CE1 . TYR A 1 183 ? 13.171  10.344  34.658  1   11.67  ? 175  TYR A CE1 1 
ATOM   1229 C  CE2 . TYR A 1 183 ? 12.179  12.025  33.211  1   13.094 ? 175  TYR A CE2 1 
ATOM   1230 C  CZ  . TYR A 1 183 ? 13.249  11.226  33.579  1   12.696 ? 175  TYR A CZ  1 
ATOM   1231 O  OH  . TYR A 1 183 ? 14.356  11.284  32.772  1   13.187 ? 175  TYR A OH  1 
ATOM   1232 N  N   . GLU A 1 184 ? 7.415   13.176  37.177  1   11.553 ? 176  GLU A N   1 
ATOM   1233 C  CA  . GLU A 1 184 ? 6.018   13.364  37.534  1   12.364 ? 176  GLU A CA  1 
ATOM   1234 C  C   . GLU A 1 184 ? 5.121   12.857  36.414  1   12.358 ? 176  GLU A C   1 
ATOM   1235 O  O   . GLU A 1 184 ? 5.408   13.065  35.221  1   12.716 ? 176  GLU A O   1 
ATOM   1236 C  CB  . GLU A 1 184 ? 5.772   14.859  37.798  1   13.199 ? 176  GLU A CB  1 
ATOM   1237 C  CG  . GLU A 1 184 ? 4.339   15.108  38.301  1   15.057 ? 176  GLU A CG  1 
ATOM   1238 C  CD  . GLU A 1 184 ? 3.974   16.554  38.608  1   17.7   ? 176  GLU A CD  1 
ATOM   1239 O  OE1 . GLU A 1 184 ? 4.808   17.409  38.292  1   18.917 ? 176  GLU A OE1 1 
ATOM   1240 O  OE2 . GLU A 1 184 ? 2.81    16.798  39.028  1   17.472 ? 176  GLU A OE2 1 
ATOM   1241 N  N   . MET A 1 185 ? 3.985   12.262  36.837  1   12.459 ? 177  MET A N   1 
ATOM   1242 C  CA  . MET A 1 185 ? 2.993   11.793  35.863  1   11.703 ? 177  MET A CA  1 
ATOM   1243 C  C   . MET A 1 185 ? 1.618   12.265  36.3    1   11.946 ? 177  MET A C   1 
ATOM   1244 O  O   . MET A 1 185 ? 1.377   12.473  37.476  1   13.69  ? 177  MET A O   1 
ATOM   1245 C  CB  . MET A 1 185 ? 2.926   10.25   35.806  1   13.257 ? 177  MET A CB  1 
ATOM   1246 C  CG  . MET A 1 185 ? 4.317   9.63    35.564  1   14.3   ? 177  MET A CG  1 
ATOM   1247 S  SD  . MET A 1 185 ? 4.34    7.841   35.831  1   15.454 ? 177  MET A SD  1 
ATOM   1248 C  CE  . MET A 1 185 ? 3.67    7.243   34.279  1   14.449 ? 177  MET A CE  1 
ATOM   1249 N  N   . ASP A 1 186 ? 0.71    12.43   35.315  1   12.368 ? 178  ASP A N   1 
ATOM   1250 C  CA  . ASP A 1 186 ? -0.691  12.693  35.619  1   11.883 ? 178  ASP A CA  1 
ATOM   1251 C  C   . ASP A 1 186 ? -1.237  11.426  36.281  1   12.465 ? 178  ASP A C   1 
ATOM   1252 O  O   . ASP A 1 186 ? -1.075  10.325  35.718  1   12.375 ? 178  ASP A O   1 
ATOM   1253 C  CB  . ASP A 1 186 ? -1.414  13.067  34.348  1   12.21  ? 178  ASP A CB  1 
ATOM   1254 C  CG  . ASP A 1 186 ? -2.865  13.418  34.576  1   16.635 ? 178  ASP A CG  1 
ATOM   1255 O  OD1 . ASP A 1 186 ? -3.697  12.502  34.798  1   14.658 ? 178  ASP A OD1 1 
ATOM   1256 O  OD2 . ASP A 1 186 ? -3.156  14.631  34.662  1   17.989 ? 178  ASP A OD2 1 
ATOM   1257 N  N   . PRO A 1 187 ? -1.965  11.522  37.412  1   12.464 ? 179  PRO A N   1 
ATOM   1258 C  CA  . PRO A 1 187 ? -2.425  10.309  38.099  1   12.267 ? 179  PRO A CA  1 
ATOM   1259 C  C   . PRO A 1 187 ? -3.602  9.6     37.415  1   12.727 ? 179  PRO A C   1 
ATOM   1260 O  O   . PRO A 1 187 ? -3.96   8.483   37.864  1   13.304 ? 179  PRO A O   1 
ATOM   1261 C  CB  . PRO A 1 187 ? -2.771  10.804  39.527  1   14.523 ? 179  PRO A CB  1 
ATOM   1262 C  CG  . PRO A 1 187 ? -3.2    12.224  39.264  1   14.539 ? 179  PRO A CG  1 
ATOM   1263 C  CD  . PRO A 1 187 ? -2.301  12.772  38.131  1   13.316 ? 179  PRO A CD  1 
ATOM   1264 N  N   . HIS A 1 188 ? -4.162  10.196  36.352  1   11.819 ? 180  HIS A N   1 
ATOM   1265 C  CA  . HIS A 1 188 ? -5.337  9.601   35.692  1   12.09  ? 180  HIS A CA  1 
ATOM   1266 C  C   . HIS A 1 188 ? -4.994  9.082   34.32   1   13.01  ? 180  HIS A C   1 
ATOM   1267 O  O   . HIS A 1 188 ? -5.394  7.97    33.976  1   12.796 ? 180  HIS A O   1 
ATOM   1268 C  CB  . HIS A 1 188 ? -6.466  10.647  35.561  1   12.294 ? 180  HIS A CB  1 
ATOM   1269 C  CG  . HIS A 1 188 ? -6.652  11.403  36.805  1   12.407 ? 180  HIS A CG  1 
ATOM   1270 N  ND1 . HIS A 1 188 ? -7.155  10.874  37.989  1   12.762 ? 180  HIS A ND1 1 
ATOM   1271 C  CD2 . HIS A 1 188 ? -6.353  12.703  37.069  1   14.474 ? 180  HIS A CD2 1 
ATOM   1272 C  CE1 . HIS A 1 188 ? -7.16   11.838  38.918  1   14.698 ? 180  HIS A CE1 1 
ATOM   1273 N  NE2 . HIS A 1 188 ? -6.703  12.964  38.366  1   14.837 ? 180  HIS A NE2 1 
ATOM   1274 N  N   . THR A 1 189 ? -4.272  9.883   33.512  1   12.593 ? 181  THR A N   1 
ATOM   1275 C  CA  . THR A 1 189 ? -3.844  9.43    32.188  1   12.505 ? 181  THR A CA  1 
ATOM   1276 C  C   . THR A 1 189 ? -2.458  8.791   32.2    1   11.659 ? 181  THR A C   1 
ATOM   1277 O  O   . THR A 1 189 ? -2.066  8.192   31.188  1   12.362 ? 181  THR A O   1 
ATOM   1278 C  CB  . THR A 1 189 ? -3.776  10.614  31.212  1   13.363 ? 181  THR A CB  1 
ATOM   1279 O  OG1 . THR A 1 189 ? -2.729  11.455  31.665  1   13.667 ? 181  THR A OG1 1 
ATOM   1280 C  CG2 . THR A 1 189 ? -5.113  11.347  31.112  1   16.091 ? 181  THR A CG2 1 
ATOM   1281 N  N   . LEU A 1 190 ? -1.697  8.993   33.286  1   11.307 ? 182  LEU A N   1 
ATOM   1282 C  CA  . LEU A 1 190 ? -0.319  8.545   33.426  1   13.58  ? 182  LEU A CA  1 
ATOM   1283 C  C   . LEU A 1 190 ? 0.585   9.241   32.403  1   13.259 ? 182  LEU A C   1 
ATOM   1284 O  O   . LEU A 1 190 ? 1.711   8.776   32.209  1   13.042 ? 182  LEU A O   1 
ATOM   1285 C  CB  . LEU A 1 190 ? -0.198  7.004   33.383  1   11.645 ? 182  LEU A CB  1 
ATOM   1286 C  CG  . LEU A 1 190 ? -0.835  6.293   34.594  1   12.113 ? 182  LEU A CG  1 
ATOM   1287 C  CD1 . LEU A 1 190 ? -0.741  4.763   34.411  1   12.26  ? 182  LEU A CD1 1 
ATOM   1288 C  CD2 . LEU A 1 190 ? -0.145  6.725   35.881  1   13.614 ? 182  LEU A CD2 1 
ATOM   1289 N  N   . LYS A 1 191 ? 0.144   10.349  31.767  1   13.201 ? 183  LYS A N   1 
ATOM   1290 C  CA  . LYS A 1 191 ? 1.046   11.096  30.88   1   13.077 ? 183  LYS A CA  1 
ATOM   1291 C  C   . LYS A 1 191 ? 2.194   11.647  31.727  1   12.928 ? 183  LYS A C   1 
ATOM   1292 O  O   . LYS A 1 191 ? 1.98    12.135  32.843  1   13.747 ? 183  LYS A O   1 
ATOM   1293 C  CB  . LYS A 1 191 ? 0.221   12.236  30.247  1   14.34  ? 183  LYS A CB  1 
ATOM   1294 C  CG  . LYS A 1 191 ? 1.031   13.074  29.244  1   16.719 ? 183  LYS A CG  1 
ATOM   1295 C  CD  . LYS A 1 191 ? 0.139   13.873  28.305  1   20.057 ? 183  LYS A CD  1 
ATOM   1296 C  CE  . LYS A 1 191 ? 0.956   14.623  27.243  1   20.42  ? 183  LYS A CE  1 
ATOM   1297 N  NZ  . LYS A 1 191 ? 1.703   13.783  26.292  1   22.427 ? 183  LYS A NZ  1 
ATOM   1298 N  N   . THR A 1 192 ? 3.386   11.667  31.165  1   12.563 ? 184  THR A N   1 
ATOM   1299 C  CA  . THR A 1 192 ? 4.507   12.222  31.9    1   12.735 ? 184  THR A CA  1 
ATOM   1300 C  C   . THR A 1 192 ? 4.489   13.754  31.792  1   13.202 ? 184  THR A C   1 
ATOM   1301 O  O   . THR A 1 192 ? 4.229   14.28   30.694  1   13.297 ? 184  THR A O   1 
ATOM   1302 C  CB  . THR A 1 192 ? 5.811   11.64   31.359  1   13.951 ? 184  THR A CB  1 
ATOM   1303 O  OG1 . THR A 1 192 ? 5.796   10.24   31.699  1   12.782 ? 184  THR A OG1 1 
ATOM   1304 C  CG2 . THR A 1 192 ? 7.044   12.242  32.027  1   13.602 ? 184  THR A CG2 1 
ATOM   1305 N  N   . LEU A 1 193 ? 4.716   14.411  32.918  1   12.758 ? 185  LEU A N   1 
ATOM   1306 C  CA  . LEU A 1 193 ? 4.595   15.88   33.004  1   13.158 ? 185  LEU A CA  1 
ATOM   1307 C  C   . LEU A 1 193 ? 5.926   16.608  33.132  1   14.804 ? 185  LEU A C   1 
ATOM   1308 O  O   . LEU A 1 193 ? 5.983   17.803  32.803  1   16.439 ? 185  LEU A O   1 
ATOM   1309 C  CB  . LEU A 1 193 ? 3.701   16.238  34.193  1   14.785 ? 185  LEU A CB  1 
ATOM   1310 C  CG  . LEU A 1 193 ? 2.295   15.616  34.128  1   13.959 ? 185  LEU A CG  1 
ATOM   1311 C  CD1 . LEU A 1 193 ? 1.519   16.061  35.322  1   14.691 ? 185  LEU A CD1 1 
ATOM   1312 C  CD2 . LEU A 1 193 ? 1.564   15.951  32.824  1   16.651 ? 185  LEU A CD2 1 
ATOM   1313 N  N   . GLY A 1 194 ? 6.943   15.964  33.717  1   14.188 ? 186  GLY A N   1 
ATOM   1314 C  CA  . GLY A 1 194 ? 8.213   16.638  33.931  1   14.826 ? 186  GLY A CA  1 
ATOM   1315 C  C   . GLY A 1 194 ? 9.153   15.831  34.801  1   15.635 ? 186  GLY A C   1 
ATOM   1316 O  O   . GLY A 1 194 ? 8.857   14.696  35.2    1   14.403 ? 186  GLY A O   1 
ATOM   1317 N  N   . TYR A 1 195 ? 10.265  16.469  35.145  1   13.477 ? 187  TYR A N   1 
ATOM   1318 C  CA  . TYR A 1 195 ? 11.331  15.843  35.9    1   12.762 ? 187  TYR A CA  1 
ATOM   1319 C  C   . TYR A 1 195 ? 11.599  16.736  37.106  1   12.703 ? 187  TYR A C   1 
ATOM   1320 O  O   . TYR A 1 195 ? 11.62   17.999  37.005  1   14.458 ? 187  TYR A O   1 
ATOM   1321 C  CB  . TYR A 1 195 ? 12.587  15.728  35.015  1   12.828 ? 187  TYR A CB  1 
ATOM   1322 C  CG  . TYR A 1 195 ? 13.805  15.212  35.759  1   13.603 ? 187  TYR A CG  1 
ATOM   1323 C  CD1 . TYR A 1 195 ? 13.998  13.832  35.994  1   13.483 ? 187  TYR A CD1 1 
ATOM   1324 C  CD2 . TYR A 1 195 ? 14.803  16.095  36.185  1   12.831 ? 187  TYR A CD2 1 
ATOM   1325 C  CE1 . TYR A 1 195 ? 15.134  13.368  36.631  1   12.897 ? 187  TYR A CE1 1 
ATOM   1326 C  CE2 . TYR A 1 195 ? 15.938  15.645  36.842  1   13.928 ? 187  TYR A CE2 1 
ATOM   1327 C  CZ  . TYR A 1 195 ? 16.107  14.276  37.066  1   12.682 ? 187  TYR A CZ  1 
ATOM   1328 O  OH  . TYR A 1 195 ? 17.23   13.812  37.722  1   13.95  ? 187  TYR A OH  1 
ATOM   1329 N  N   . ASN A 1 196 ? 11.91   16.095  38.246  1   12.041 ? 188  ASN A N   1 
ATOM   1330 C  CA  . ASN A 1 196 ? 12.333  16.779  39.473  1   14.15  ? 188  ASN A CA  1 
ATOM   1331 C  C   . ASN A 1 196 ? 11.298  17.824  39.894  1   14.426 ? 188  ASN A C   1 
ATOM   1332 O  O   . ASN A 1 196 ? 11.634  19.027  40.029  1   15.192 ? 188  ASN A O   1 
ATOM   1333 C  CB  . ASN A 1 196 ? 13.744  17.368  39.334  1   13.37  ? 188  ASN A CB  1 
ATOM   1334 C  CG  . ASN A 1 196 ? 14.366  17.786  40.648  1   13.001 ? 188  ASN A CG  1 
ATOM   1335 O  OD1 . ASN A 1 196 ? 13.887  17.482  41.742  1   13.916 ? 188  ASN A OD1 1 
ATOM   1336 N  ND2 . ASN A 1 196 ? 15.495  18.463  40.545  1   13.732 ? 188  ASN A ND2 1 
ATOM   1337 N  N   . PRO A 1 197 ? 10.017  17.452  40.121  1   15.03  ? 189  PRO A N   1 
ATOM   1338 C  CA  . PRO A 1 197 ? 8.986   18.442  40.434  1   15.55  ? 189  PRO A CA  1 
ATOM   1339 C  C   . PRO A 1 197 ? 9.188   19.279  41.688  1   14.309 ? 189  PRO A C   1 
ATOM   1340 O  O   . PRO A 1 197 ? 8.747   20.417  41.726  1   18.856 ? 189  PRO A O   1 
ATOM   1341 C  CB  . PRO A 1 197 ? 7.706   17.539  40.559  1   17.39  ? 189  PRO A CB  1 
ATOM   1342 C  CG  . PRO A 1 197 ? 8.222   16.153  40.879  1   16.724 ? 189  PRO A CG  1 
ATOM   1343 C  CD  . PRO A 1 197 ? 9.504   16.07   40.057  1   14.614 ? 189  PRO A CD  1 
ATOM   1344 N  N   . PHE A 1 198 ? 9.933   18.732  42.662  1   13.456 ? 190  PHE A N   1 
ATOM   1345 C  CA  . PHE A 1 198 ? 10.202  19.431  43.902  1   13.581 ? 190  PHE A CA  1 
ATOM   1346 C  C   . PHE A 1 198 ? 11.519  20.211  43.827  1   13.645 ? 190  PHE A C   1 
ATOM   1347 O  O   . PHE A 1 198 ? 11.904  20.802  44.855  1   14.494 ? 190  PHE A O   1 
ATOM   1348 C  CB  . PHE A 1 198 ? 10.148  18.486  45.119  1   14.626 ? 190  PHE A CB  1 
ATOM   1349 C  CG  . PHE A 1 198 ? 8.737   17.937  45.303  1   14.589 ? 190  PHE A CG  1 
ATOM   1350 C  CD1 . PHE A 1 198 ? 7.614   18.783  45.372  1   16.258 ? 190  PHE A CD1 1 
ATOM   1351 C  CD2 . PHE A 1 198 ? 8.551   16.552  45.388  1   15.758 ? 190  PHE A CD2 1 
ATOM   1352 C  CE1 . PHE A 1 198 ? 6.336   18.253  45.582  1   18.186 ? 190  PHE A CE1 1 
ATOM   1353 C  CE2 . PHE A 1 198 ? 7.295   16.016  45.519  1   16.52  ? 190  PHE A CE2 1 
ATOM   1354 C  CZ  . PHE A 1 198 ? 6.186   16.855  45.63   1   16.404 ? 190  PHE A CZ  1 
ATOM   1355 N  N   A ASN A 1 199 ? 12.203  20.185  42.673  0.5 13.96  ? 191  ASN A N   1 
ATOM   1356 N  N   B ASN A 1 199 ? 12.205  20.2    42.672  0.5 15.209 ? 191  ASN A N   1 
ATOM   1357 C  CA  A ASN A 1 199 ? 13.411  20.982  42.43   0.5 13.708 ? 191  ASN A CA  1 
ATOM   1358 C  CA  B ASN A 1 199 ? 13.42   20.995  42.455  0.5 15.828 ? 191  ASN A CA  1 
ATOM   1359 C  C   A ASN A 1 199 ? 14.461  20.696  43.498  0.5 15.118 ? 191  ASN A C   1 
ATOM   1360 C  C   B ASN A 1 199 ? 14.464  20.695  43.518  0.5 16.377 ? 191  ASN A C   1 
ATOM   1361 O  O   A ASN A 1 199 ? 15.099  21.61   43.999  0.5 15.29  ? 191  ASN A O   1 
ATOM   1362 O  O   B ASN A 1 199 ? 15.085  21.609  44.045  0.5 16.226 ? 191  ASN A O   1 
ATOM   1363 C  CB  A ASN A 1 199 ? 13.08   22.477  42.277  0.5 15.061 ? 191  ASN A CB  1 
ATOM   1364 C  CB  B ASN A 1 199 ? 13.143  22.507  42.47   0.5 20.014 ? 191  ASN A CB  1 
ATOM   1365 C  CG  A ASN A 1 199 ? 14.265  23.269  41.762  0.5 13.853 ? 191  ASN A CG  1 
ATOM   1366 C  CG  B ASN A 1 199 ? 12.311  22.886  41.277  0.5 20.712 ? 191  ASN A CG  1 
ATOM   1367 O  OD1 A ASN A 1 199 ? 15.045  22.762  40.946  0.5 15.2   ? 191  ASN A OD1 1 
ATOM   1368 O  OD1 B ASN A 1 199 ? 12.676  22.547  40.15   0.5 25.692 ? 191  ASN A OD1 1 
ATOM   1369 N  ND2 A ASN A 1 199 ? 14.405  24.501  42.247  0.5 15.322 ? 191  ASN A ND2 1 
ATOM   1370 N  ND2 B ASN A 1 199 ? 11.186  23.543  41.5    0.5 29.172 ? 191  ASN A ND2 1 
ATOM   1371 N  N   . LEU A 1 200 ? 14.678  19.402  43.819  1   15.161 ? 192  LEU A N   1 
ATOM   1372 C  CA  . LEU A 1 200 ? 15.722  19.034  44.746  1   14.191 ? 192  LEU A CA  1 
ATOM   1373 C  C   . LEU A 1 200 ? 17.08   19.395  44.126  1   14.968 ? 192  LEU A C   1 
ATOM   1374 O  O   . LEU A 1 200 ? 17.288  19.275  42.919  1   14.538 ? 192  LEU A O   1 
ATOM   1375 C  CB  . LEU A 1 200 ? 15.679  17.543  45.08   1   14.768 ? 192  LEU A CB  1 
ATOM   1376 C  CG  . LEU A 1 200 ? 14.377  17.1    45.745  1   13.97  ? 192  LEU A CG  1 
ATOM   1377 C  CD1 . LEU A 1 200 ? 14.582  15.671  46.191  1   15.109 ? 192  LEU A CD1 1 
ATOM   1378 C  CD2 . LEU A 1 200 ? 13.945  17.962  46.941  1   14.411 ? 192  LEU A CD2 1 
ATOM   1379 N  N   . PRO A 1 201 ? 18.035  19.849  44.961  1   13.496 ? 193  PRO A N   1 
ATOM   1380 C  CA  . PRO A 1 201 ? 19.34   20.238  44.434  1   14.335 ? 193  PRO A CA  1 
ATOM   1381 C  C   . PRO A 1 201 ? 20.341  19.13   44.182  1   16.552 ? 193  PRO A C   1 
ATOM   1382 O  O   . PRO A 1 201 ? 21.407  19.378  43.602  1   15.784 ? 193  PRO A O   1 
ATOM   1383 C  CB  . PRO A 1 201 ? 19.796  21.228  45.54   1   14.285 ? 193  PRO A CB  1 
ATOM   1384 C  CG  . PRO A 1 201 ? 19.257  20.59   46.832  1   14.996 ? 193  PRO A CG  1 
ATOM   1385 C  CD  . PRO A 1 201 ? 17.861  20.198  46.371  1   14.44  ? 193  PRO A CD  1 
ATOM   1386 N  N   . SER A 1 202 ? 20.037  17.919  44.667  1   14.72  ? 194  SER A N   1 
ATOM   1387 C  CA  . SER A 1 202 ? 20.859  16.744  44.427  1   14.117 ? 194  SER A CA  1 
ATOM   1388 C  C   . SER A 1 202 ? 20.606  16.231  43.017  1   13.52  ? 194  SER A C   1 
ATOM   1389 O  O   . SER A 1 202 ? 19.585  16.573  42.376  1   13.474 ? 194  SER A O   1 
ATOM   1390 C  CB  . SER A 1 202 ? 20.504  15.714  45.491  1   13.937 ? 194  SER A CB  1 
ATOM   1391 O  OG  . SER A 1 202 ? 19.092  15.528  45.527  1   15.153 ? 194  SER A OG  1 
ATOM   1392 N  N   . LYS A 1 203 ? 21.507  15.353  42.563  1   12.683 ? 195  LYS A N   1 
ATOM   1393 C  CA  . LYS A 1 203 ? 21.348  14.693  41.269  1   14.071 ? 195  LYS A CA  1 
ATOM   1394 C  C   . LYS A 1 203 ? 20.465  13.437  41.381  1   13.885 ? 195  LYS A C   1 
ATOM   1395 O  O   . LYS A 1 203 ? 20.047  12.893  40.355  1   15.051 ? 195  LYS A O   1 
ATOM   1396 C  CB  . LYS A 1 203 ? 22.724  14.285  40.732  1   16.706 ? 195  LYS A CB  1 
ATOM   1397 C  CG  . LYS A 1 203 ? 23.5    15.536  40.3    1   21.009 ? 195  LYS A CG  1 
ATOM   1398 C  CD  . LYS A 1 203 ? 24.721  15.224  39.453  1   22.119 ? 195  LYS A CD  1 
ATOM   1399 C  CE  . LYS A 1 203 ? 25.518  16.49   39.322  1   24.159 ? 195  LYS A CE  1 
ATOM   1400 N  NZ  . LYS A 1 203 ? 26.221  16.518  38.036  1   32.625 ? 195  LYS A NZ  1 
ATOM   1401 N  N   . THR A 1 204 ? 20.108  13.05   42.609  1   13.49  ? 196  THR A N   1 
ATOM   1402 C  CA  . THR A 1 204 ? 19.381  11.81   42.873  1   13.882 ? 196  THR A CA  1 
ATOM   1403 C  C   . THR A 1 204 ? 18.342  12.058  43.947  1   12.483 ? 196  THR A C   1 
ATOM   1404 O  O   . THR A 1 204 ? 18.464  12.953  44.784  1   13.336 ? 196  THR A O   1 
ATOM   1405 C  CB  . THR A 1 204 ? 20.325  10.705  43.343  1   12.999 ? 196  THR A CB  1 
ATOM   1406 O  OG1 . THR A 1 204 ? 20.891  11.15   44.579  1   14.274 ? 196  THR A OG1 1 
ATOM   1407 C  CG2 . THR A 1 204 ? 21.401  10.398  42.301  1   13.376 ? 196  THR A CG2 1 
ATOM   1408 N  N   . MET A 1 205 ? 17.35   11.161  43.983  1   12.883 ? 197  MET A N   1 
ATOM   1409 C  CA  . MET A 1 205 ? 16.423  11.073  45.1    1   12.495 ? 197  MET A CA  1 
ATOM   1410 C  C   . MET A 1 205 ? 16.14   9.579   45.282  1   12.467 ? 197  MET A C   1 
ATOM   1411 O  O   . MET A 1 205 ? 15.951  8.835   44.303  1   12.406 ? 197  MET A O   1 
ATOM   1412 C  CB  . MET A 1 205 ? 15.084  11.79   44.806  1   11.36  ? 197  MET A CB  1 
ATOM   1413 C  CG  . MET A 1 205 ? 14.216  11.797  46.078  1   11.221 ? 197  MET A CG  1 
ATOM   1414 S  SD  . MET A 1 205 ? 12.539  12.434  45.83   1   13.075 ? 197  MET A SD  1 
ATOM   1415 C  CE  . MET A 1 205 ? 11.838  11.005  45.013  1   13.545 ? 197  MET A CE  1 
ATOM   1416 N  N   . THR A 1 206 ? 16.114  9.147   46.545  1   12.735 ? 198  THR A N   1 
ATOM   1417 C  CA  . THR A 1 206 ? 15.745  7.774   46.869  1   11.994 ? 198  THR A CA  1 
ATOM   1418 C  C   . THR A 1 206 ? 14.39   7.447   46.282  1   13.07  ? 198  THR A C   1 
ATOM   1419 O  O   . THR A 1 206 ? 13.523  8.328   46.171  1   12.881 ? 198  THR A O   1 
ATOM   1420 C  CB  . THR A 1 206 ? 15.725  7.632   48.393  1   12.395 ? 198  THR A CB  1 
ATOM   1421 O  OG1 . THR A 1 206 ? 15.468  6.264   48.734  1   11.842 ? 198  THR A OG1 1 
ATOM   1422 C  CG2 . THR A 1 206 ? 14.643  8.446   49.098  1   11.581 ? 198  THR A CG2 1 
ATOM   1423 N  N   . ALA A 1 207 ? 14.217  6.158   45.972  1   11.794 ? 199  ALA A N   1 
ATOM   1424 C  CA  . ALA A 1 207 ? 12.895  5.676   45.635  1   11.877 ? 199  ALA A CA  1 
ATOM   1425 C  C   . ALA A 1 207 ? 12.163  5.17    46.873  1   12.429 ? 199  ALA A C   1 
ATOM   1426 O  O   . ALA A 1 207 ? 11.034  4.663   46.739  1   12.874 ? 199  ALA A O   1 
ATOM   1427 C  CB  . ALA A 1 207 ? 12.989  4.634   44.542  1   14.553 ? 199  ALA A CB  1 
ATOM   1428 N  N   . HIS A 1 208 ? 12.747  5.335   48.07   1   12.57  ? 200  HIS A N   1 
ATOM   1429 C  CA  . HIS A 1 208 ? 12.101  4.9     49.309  1   11.706 ? 200  HIS A CA  1 
ATOM   1430 C  C   . HIS A 1 208 ? 11.98   6.097   50.263  1   13.014 ? 200  HIS A C   1 
ATOM   1431 O  O   . HIS A 1 208 ? 12.342  6.003   51.435  1   12.863 ? 200  HIS A O   1 
ATOM   1432 C  CB  . HIS A 1 208 ? 12.867  3.705   49.947  1   11.751 ? 200  HIS A CB  1 
ATOM   1433 C  CG  . HIS A 1 208 ? 12.581  2.434   49.228  1   12.44  ? 200  HIS A CG  1 
ATOM   1434 N  ND1 . HIS A 1 208 ? 11.318  1.914   49.343  1   12.892 ? 200  HIS A ND1 1 
ATOM   1435 C  CD2 . HIS A 1 208 ? 13.29   1.613   48.443  1   11.974 ? 200  HIS A CD2 1 
ATOM   1436 C  CE1 . HIS A 1 208 ? 11.245  0.815   48.647  1   12.789 ? 200  HIS A CE1 1 
ATOM   1437 N  NE2 . HIS A 1 208 ? 12.441  0.601   48.059  1   12.914 ? 200  HIS A NE2 1 
ATOM   1438 N  N   . PRO A 1 209 ? 11.4    7.259   49.853  1   12.402 ? 201  PRO A N   1 
ATOM   1439 C  CA  . PRO A 1 209 ? 11.088  8.286   50.848  1   12.163 ? 201  PRO A CA  1 
ATOM   1440 C  C   . PRO A 1 209 ? 9.929   7.801   51.715  1   11.916 ? 201  PRO A C   1 
ATOM   1441 O  O   . PRO A 1 209 ? 9.19    6.885   51.324  1   13.334 ? 201  PRO A O   1 
ATOM   1442 C  CB  . PRO A 1 209 ? 10.73   9.44    49.933  1   11.334 ? 201  PRO A CB  1 
ATOM   1443 C  CG  . PRO A 1 209 ? 9.964   8.784   48.79   1   12.039 ? 201  PRO A CG  1 
ATOM   1444 C  CD  . PRO A 1 209 ? 10.778  7.538   48.54   1   12.036 ? 201  PRO A CD  1 
ATOM   1445 N  N   . LYS A 1 210 ? 9.724   8.463   52.848  1   11.673 ? 202  LYS A N   1 
ATOM   1446 C  CA  . LYS A 1 210 ? 8.66    8.037   53.776  1   10.948 ? 202  LYS A CA  1 
ATOM   1447 C  C   . LYS A 1 210 ? 7.788   9.255   54.049  1   12.002 ? 202  LYS A C   1 
ATOM   1448 O  O   . LYS A 1 210 ? 8.349   10.328  54.314  1   14.329 ? 202  LYS A O   1 
ATOM   1449 C  CB  . LYS A 1 210 ? 9.213   7.492   55.108  1   11.733 ? 202  LYS A CB  1 
ATOM   1450 C  CG  . LYS A 1 210 ? 10.35   6.427   54.915  1   13.004 ? 202  LYS A CG  1 
ATOM   1451 C  CD  . LYS A 1 210 ? 9.886   5.128   54.266  1   11.905 ? 202  LYS A CD  1 
ATOM   1452 C  CE  . LYS A 1 210 ? 11.068  4.26    53.927  1   12.376 ? 202  LYS A CE  1 
ATOM   1453 N  NZ  . LYS A 1 210 ? 10.706  2.924   53.38   1   13.177 ? 202  LYS A NZ  1 
ATOM   1454 N  N   . GLN A 1 211 ? 6.466   9.108   54.017  1   11.713 ? 203  GLN A N   1 
ATOM   1455 C  CA  . GLN A 1 211 ? 5.553   10.203  54.349  1   12.463 ? 203  GLN A CA  1 
ATOM   1456 C  C   . GLN A 1 211 ? 5.192   10.142  55.815  1   13.115 ? 203  GLN A C   1 
ATOM   1457 O  O   . GLN A 1 211 ? 4.467   9.271   56.282  1   13.714 ? 203  GLN A O   1 
ATOM   1458 C  CB  . GLN A 1 211 ? 4.346   10.101  53.427  1   12.264 ? 203  GLN A CB  1 
ATOM   1459 C  CG  . GLN A 1 211 ? 4.7     10.607  52.036  1   13.5   ? 203  GLN A CG  1 
ATOM   1460 C  CD  . GLN A 1 211 ? 3.517   10.545  51.097  1   14.498 ? 203  GLN A CD  1 
ATOM   1461 O  OE1 . GLN A 1 211 ? 2.982   9.465   50.813  1   14.426 ? 203  GLN A OE1 1 
ATOM   1462 N  NE2 . GLN A 1 211 ? 3.195   11.669  50.47   1   14.232 ? 203  GLN A NE2 1 
ATOM   1463 N  N   . CYS A 1 212 ? 5.74    11.106  56.557  1   12.987 ? 204  CYS A N   1 
ATOM   1464 C  CA  . CYS A 1 212 ? 5.598   11.207  58.009  1   15.178 ? 204  CYS A CA  1 
ATOM   1465 C  C   . CYS A 1 212 ? 4.122   11.392  58.395  1   14.98  ? 204  CYS A C   1 
ATOM   1466 O  O   . CYS A 1 212 ? 3.496   12.321  57.906  1   15.386 ? 204  CYS A O   1 
ATOM   1467 C  CB  . CYS A 1 212 ? 6.409   12.428  58.443  1   15.301 ? 204  CYS A CB  1 
ATOM   1468 S  SG  . CYS A 1 212 ? 6.321   12.775  60.236  1   15.431 ? 204  CYS A SG  1 
ATOM   1469 N  N   . SER A 1 213 ? 3.604   10.536  59.272  1   14.512 ? 205  SER A N   1 
ATOM   1470 C  CA  . SER A 1 213 ? 2.213   10.649  59.709  1   14.426 ? 205  SER A CA  1 
ATOM   1471 C  C   . SER A 1 213 ? 1.995   11.867  60.619  1   17.181 ? 205  SER A C   1 
ATOM   1472 O  O   . SER A 1 213 ? 0.835   12.258  60.79   1   19.759 ? 205  SER A O   1 
ATOM   1473 C  CB  . SER A 1 213 ? 1.745   9.361   60.379  1   14.89  ? 205  SER A CB  1 
ATOM   1474 O  OG  . SER A 1 213 ? 2.466   9.135   61.574  1   16.347 ? 205  SER A OG  1 
ATOM   1475 N  N   . VAL A 1 214 ? 3.052   12.445  61.21   1   17.265 ? 206  VAL A N   1 
ATOM   1476 C  CA  . VAL A 1 214 ? 2.863   13.554  62.144  1   18.439 ? 206  VAL A CA  1 
ATOM   1477 C  C   . VAL A 1 214 ? 2.89    14.884  61.391  1   19.556 ? 206  VAL A C   1 
ATOM   1478 O  O   . VAL A 1 214 ? 1.975   15.709  61.571  1   22.305 ? 206  VAL A O   1 
ATOM   1479 C  CB  . VAL A 1 214 ? 3.94    13.466  63.24   1   18.811 ? 206  VAL A CB  1 
ATOM   1480 C  CG1 . VAL A 1 214 ? 3.969   14.699  64.159  1   21.333 ? 206  VAL A CG1 1 
ATOM   1481 C  CG2 . VAL A 1 214 ? 3.747   12.21   64.096  1   20.082 ? 206  VAL A CG2 1 
ATOM   1482 N  N   . THR A 1 215 ? 3.939   15.1    60.582  1   17.532 ? 207  THR A N   1 
ATOM   1483 C  CA  . THR A 1 215 ? 4.108   16.352  59.865  1   17.345 ? 207  THR A CA  1 
ATOM   1484 C  C   . THR A 1 215 ? 3.438   16.334  58.497  1   16.13  ? 207  THR A C   1 
ATOM   1485 O  O   . THR A 1 215 ? 3.279   17.408  57.909  1   18.748 ? 207  THR A O   1 
ATOM   1486 C  CB  . THR A 1 215 ? 5.58    16.727  59.707  1   17.101 ? 207  THR A CB  1 
ATOM   1487 O  OG1 . THR A 1 215 ? 6.189   15.677  58.938  1   15.934 ? 207  THR A OG1 1 
ATOM   1488 C  CG2 . THR A 1 215 ? 6.313   16.828  61.042  1   18.5   ? 207  THR A CG2 1 
ATOM   1489 N  N   . GLY A 1 216 ? 3.266   15.142  57.883  1   15.738 ? 208  GLY A N   1 
ATOM   1490 C  CA  . GLY A 1 216 ? 2.904   15.053  56.475  1   14.034 ? 208  GLY A CA  1 
ATOM   1491 C  C   . GLY A 1 216 ? 4.111   15.24   55.542  1   13.656 ? 208  GLY A C   1 
ATOM   1492 O  O   . GLY A 1 216 ? 3.922   15.226  54.332  1   16.429 ? 208  GLY A O   1 
ATOM   1493 N  N   . ASN A 1 217 ? 5.32    15.415  56.1    1   13.922 ? 209  ASN A N   1 
ATOM   1494 C  CA  . ASN A 1 217 ? 6.472   15.656  55.231  1   14     ? 209  ASN A CA  1 
ATOM   1495 C  C   . ASN A 1 217 ? 6.858   14.382  54.466  1   13.36  ? 209  ASN A C   1 
ATOM   1496 O  O   . ASN A 1 217 ? 6.78    13.271  55.008  1   13.87  ? 209  ASN A O   1 
ATOM   1497 C  CB  . ASN A 1 217 ? 7.701   16.078  56.037  1   13.942 ? 209  ASN A CB  1 
ATOM   1498 C  CG  . ASN A 1 217 ? 7.569   17.454  56.674  1   15.206 ? 209  ASN A CG  1 
ATOM   1499 O  OD1 . ASN A 1 217 ? 6.599   18.185  56.414  1   16.267 ? 209  ASN A OD1 1 
ATOM   1500 N  ND2 . ASN A 1 217 ? 8.562   17.784  57.495  1   13.644 ? 209  ASN A ND2 1 
ATOM   1501 N  N   . LEU A 1 218 ? 7.312   14.582  53.216  1   13.209 ? 210  LEU A N   1 
ATOM   1502 C  CA  . LEU A 1 218 ? 8.023   13.537  52.476  1   12.019 ? 210  LEU A CA  1 
ATOM   1503 C  C   . LEU A 1 218 ? 9.483   13.583  52.925  1   13.373 ? 210  LEU A C   1 
ATOM   1504 O  O   . LEU A 1 218 ? 10.2    14.566  52.632  1   13.526 ? 210  LEU A O   1 
ATOM   1505 C  CB  . LEU A 1 218 ? 7.923   13.842  50.981  1   12.873 ? 210  LEU A CB  1 
ATOM   1506 C  CG  . LEU A 1 218 ? 8.496   12.771  50.029  1   13.66  ? 210  LEU A CG  1 
ATOM   1507 C  CD1 . LEU A 1 218 ? 7.652   11.499  50.016  1   14.975 ? 210  LEU A CD1 1 
ATOM   1508 C  CD2 . LEU A 1 218 ? 8.673   13.313  48.63   1   14.768 ? 210  LEU A CD2 1 
ATOM   1509 N  N   . VAL A 1 219 ? 9.924   12.552  53.656  1   11.43  ? 211  VAL A N   1 
ATOM   1510 C  CA  . VAL A 1 219 ? 11.239  12.56   54.285  1   11.75  ? 211  VAL A CA  1 
ATOM   1511 C  C   . VAL A 1 219 ? 12.1    11.583  53.481  1   12.984 ? 211  VAL A C   1 
ATOM   1512 O  O   . VAL A 1 219 ? 11.706  10.433  53.259  1   13.476 ? 211  VAL A O   1 
ATOM   1513 C  CB  . VAL A 1 219 ? 11.149  12.141  55.753  1   14.076 ? 211  VAL A CB  1 
ATOM   1514 C  CG1 . VAL A 1 219 ? 12.553  12.176  56.375  1   14.002 ? 211  VAL A CG1 1 
ATOM   1515 C  CG2 . VAL A 1 219 ? 10.182  12.998  56.57   1   13.137 ? 211  VAL A CG2 1 
ATOM   1516 N  N   . GLY A 1 220 ? 13.256  12.053  53.016  1   11.82  ? 212  GLY A N   1 
ATOM   1517 C  CA  . GLY A 1 220 ? 14.11   11.145  52.256  1   11.322 ? 212  GLY A CA  1 
ATOM   1518 C  C   . GLY A 1 220 ? 15.525  11.672  52.135  1   11.706 ? 212  GLY A C   1 
ATOM   1519 O  O   . GLY A 1 220 ? 15.979  12.509  52.926  1   12.658 ? 212  GLY A O   1 
ATOM   1520 N  N   . PHE A 1 221 ? 16.199  11.152  51.124  1   11.932 ? 213  PHE A N   1 
ATOM   1521 C  CA  . PHE A 1 221 ? 17.61   11.426  50.886  1   11.646 ? 213  PHE A CA  1 
ATOM   1522 C  C   . PHE A 1 221 ? 17.887  11.111  49.442  1   12.553 ? 213  PHE A C   1 
ATOM   1523 O  O   . PHE A 1 221 ? 17.08   10.494  48.783  1   12.185 ? 213  PHE A O   1 
ATOM   1524 C  CB  . PHE A 1 221 ? 18.51   10.586  51.825  1   11.563 ? 213  PHE A CB  1 
ATOM   1525 C  CG  . PHE A 1 221 ? 18.396  9.096   51.571  1   11.576 ? 213  PHE A CG  1 
ATOM   1526 C  CD1 . PHE A 1 221 ? 17.267  8.416   52.026  1   11.754 ? 213  PHE A CD1 1 
ATOM   1527 C  CD2 . PHE A 1 221 ? 19.383  8.445   50.827  1   11.525 ? 213  PHE A CD2 1 
ATOM   1528 C  CE1 . PHE A 1 221 ? 17.088  7.054   51.723  1   11.493 ? 213  PHE A CE1 1 
ATOM   1529 C  CE2 . PHE A 1 221 ? 19.22   7.069   50.55   1   12.409 ? 213  PHE A CE2 1 
ATOM   1530 C  CZ  . PHE A 1 221 ? 18.077  6.367   50.98   1   12.229 ? 213  PHE A CZ  1 
ATOM   1531 N  N   . GLY A 1 222 ? 19.05   11.555  48.966  1   11.503 ? 214  GLY A N   1 
ATOM   1532 C  CA  . GLY A 1 222 ? 19.625  11.083  47.716  1   12.419 ? 214  GLY A CA  1 
ATOM   1533 C  C   . GLY A 1 222 ? 21.088  10.758  47.978  1   12.927 ? 214  GLY A C   1 
ATOM   1534 O  O   . GLY A 1 222 ? 21.767  11.548  48.633  1   15.083 ? 214  GLY A O   1 
ATOM   1535 N  N   . TYR A 1 223 ? 21.556  9.598   47.536  1   12.239 ? 215  TYR A N   1 
ATOM   1536 C  CA  . TYR A 1 223 ? 22.981  9.277   47.666  1   12.997 ? 215  TYR A CA  1 
ATOM   1537 C  C   . TYR A 1 223 ? 23.611  9.291   46.271  1   12.989 ? 215  TYR A C   1 
ATOM   1538 O  O   . TYR A 1 223 ? 22.931  9.444   45.242  1   12.162 ? 215  TYR A O   1 
ATOM   1539 C  CB  . TYR A 1 223 ? 23.213  7.986   48.456  1   13.634 ? 215  TYR A CB  1 
ATOM   1540 C  CG  . TYR A 1 223 ? 22.874  6.729   47.659  1   12.212 ? 215  TYR A CG  1 
ATOM   1541 C  CD1 . TYR A 1 223 ? 21.551  6.266   47.539  1   13.88  ? 215  TYR A CD1 1 
ATOM   1542 C  CD2 . TYR A 1 223 ? 23.89   6.022   46.98   1   12.375 ? 215  TYR A CD2 1 
ATOM   1543 C  CE1 . TYR A 1 223 ? 21.235  5.124   46.783  1   12.536 ? 215  TYR A CE1 1 
ATOM   1544 C  CE2 . TYR A 1 223 ? 23.553  4.901   46.214  1   13.963 ? 215  TYR A CE2 1 
ATOM   1545 C  CZ  . TYR A 1 223 ? 22.245  4.472   46.107  1   12.957 ? 215  TYR A CZ  1 
ATOM   1546 O  OH  . TYR A 1 223 ? 21.945  3.35    45.355  1   14.009 ? 215  TYR A OH  1 
ATOM   1547 N  N   . GLU A 1 224 ? 24.944  9.198   46.213  1   12.483 ? 216  GLU A N   1 
ATOM   1548 C  CA  . GLU A 1 224 ? 25.659  9.604   44.996  1   13.685 ? 216  GLU A CA  1 
ATOM   1549 C  C   . GLU A 1 224 ? 25.127  10.961  44.542  1   13.299 ? 216  GLU A C   1 
ATOM   1550 O  O   . GLU A 1 224 ? 24.922  11.239  43.363  1   13.234 ? 216  GLU A O   1 
ATOM   1551 C  CB  . GLU A 1 224 ? 25.661  8.579   43.867  1   14.22  ? 216  GLU A CB  1 
ATOM   1552 C  CG  . GLU A 1 224 ? 26.265  7.26    44.328  1   13.222 ? 216  GLU A CG  1 
ATOM   1553 C  CD  . GLU A 1 224 ? 26.693  6.274   43.25   1   14.03  ? 216  GLU A CD  1 
ATOM   1554 O  OE1 . GLU A 1 224 ? 26.885  6.655   42.07   1   13.61  ? 216  GLU A OE1 1 
ATOM   1555 O  OE2 . GLU A 1 224 ? 26.762  5.07    43.578  1   15.693 ? 216  GLU A OE2 1 
ATOM   1556 N  N   . ALA A 1 225 ? 24.939  11.867  45.52   1   13.046 ? 217  ALA A N   1 
ATOM   1557 C  CA  . ALA A 1 225 ? 24.114  13.043  45.275  1   12.993 ? 217  ALA A CA  1 
ATOM   1558 C  C   . ALA A 1 225 ? 24.799  14.097  44.419  1   14.045 ? 217  ALA A C   1 
ATOM   1559 O  O   . ALA A 1 225 ? 24.105  14.974  43.932  1   14.949 ? 217  ALA A O   1 
ATOM   1560 C  CB  . ALA A 1 225 ? 23.654  13.637  46.577  1   14.022 ? 217  ALA A CB  1 
ATOM   1561 N  N   . LYS A 1 226 ? 26.123  13.951  44.203  1   15.219 ? 218  LYS A N   1 
ATOM   1562 C  CA  . LYS A 1 226 ? 26.883  14.898  43.371  1   15.445 ? 218  LYS A CA  1 
ATOM   1563 C  C   . LYS A 1 226 ? 27.399  14.207  42.12   1   18.09  ? 218  LYS A C   1 
ATOM   1564 O  O   . LYS A 1 226 ? 28.204  14.802  41.392  1   19.762 ? 218  LYS A O   1 
ATOM   1565 C  CB  . LYS A 1 226 ? 28.019  15.55   44.19   1   16.039 ? 218  LYS A CB  1 
ATOM   1566 C  CG  . LYS A 1 226 ? 27.462  16.427  45.319  1   16.348 ? 218  LYS A CG  1 
ATOM   1567 C  CD  . LYS A 1 226 ? 28.5    17.401  45.876  1   18.629 ? 218  LYS A CD  1 
ATOM   1568 C  CE  . LYS A 1 226 ? 27.954  18.122  46.984  1   17.492 ? 218  LYS A CE  1 
ATOM   1569 N  NZ  . LYS A 1 226 ? 28.776  19.303  47.364  1   21.623 ? 218  LYS A NZ  1 
ATOM   1570 N  N   . GLY A 1 227 ? 26.913  12.997  41.804  1   14.365 ? 219  GLY A N   1 
ATOM   1571 C  CA  . GLY A 1 227 ? 27.262  12.32   40.56   1   16.708 ? 219  GLY A CA  1 
ATOM   1572 C  C   . GLY A 1 227 ? 27.859  10.941  40.795  1   14.793 ? 219  GLY A C   1 
ATOM   1573 O  O   . GLY A 1 227 ? 27.916  10.422  41.937  1   14.409 ? 219  GLY A O   1 
ATOM   1574 N  N   . LEU A 1 228 ? 28.278  10.296  39.697  1   15.772 ? 220  LEU A N   1 
ATOM   1575 C  CA  . LEU A 1 228 ? 28.659  8.898   39.742  1   17.022 ? 220  LEU A CA  1 
ATOM   1576 C  C   . LEU A 1 228 ? 29.76   8.637   40.773  1   17.421 ? 220  LEU A C   1 
ATOM   1577 O  O   . LEU A 1 228 ? 30.811  9.294   40.755  1   17.847 ? 220  LEU A O   1 
ATOM   1578 C  CB  . LEU A 1 228 ? 29.192  8.619   38.332  1   18.858 ? 220  LEU A CB  1 
ATOM   1579 C  CG  . LEU A 1 228 ? 29.135  7.187   37.838  1   23.43  ? 220  LEU A CG  1 
ATOM   1580 C  CD1 . LEU A 1 228 ? 27.696  6.605   37.743  1   16.476 ? 220  LEU A CD1 1 
ATOM   1581 C  CD2 . LEU A 1 228 ? 29.678  7.354   36.423  1   22.98  ? 220  LEU A CD2 1 
ATOM   1582 N  N   . ALA A 1 229 ? 29.513  7.664   41.671  1   15.707 ? 221  ALA A N   1 
ATOM   1583 C  CA  . ALA A 1 229 ? 30.45   7.152   42.667  1   16.227 ? 221  ALA A CA  1 
ATOM   1584 C  C   . ALA A 1 229 ? 30.77   8.175   43.765  1   16.784 ? 221  ALA A C   1 
ATOM   1585 O  O   . ALA A 1 229 ? 31.639  7.916   44.608  1   19.727 ? 221  ALA A O   1 
ATOM   1586 C  CB  . ALA A 1 229 ? 31.742  6.568   42.054  1   17.555 ? 221  ALA A CB  1 
ATOM   1587 N  N   . THR A 1 230 ? 30.003  9.265   43.839  1   14.571 ? 222  THR A N   1 
ATOM   1588 C  CA  . THR A 1 230 ? 30.201  10.252  44.913  1   14.355 ? 222  THR A CA  1 
ATOM   1589 C  C   . THR A 1 230 ? 29.698  9.716   46.249  1   14.266 ? 222  THR A C   1 
ATOM   1590 O  O   . THR A 1 230 ? 28.683  8.994   46.317  1   14.785 ? 222  THR A O   1 
ATOM   1591 C  CB  . THR A 1 230 ? 29.698  11.657  44.587  1   14.841 ? 222  THR A CB  1 
ATOM   1592 O  OG1 . THR A 1 230 ? 28.271  11.666  44.392  1   15.276 ? 222  THR A OG1 1 
ATOM   1593 C  CG2 . THR A 1 230 ? 30.396  12.246  43.362  1   14.115 ? 222  THR A CG2 1 
ATOM   1594 N  N   . LYS A 1 231 ? 30.424  10.094  47.332  1   14.95  ? 223  LYS A N   1 
ATOM   1595 C  CA  . LYS A 1 231 ? 30.009  9.691   48.678  1   15.333 ? 223  LYS A CA  1 
ATOM   1596 C  C   . LYS A 1 231 ? 28.914  10.592  49.262  1   14.599 ? 223  LYS A C   1 
ATOM   1597 O  O   . LYS A 1 231 ? 28.336  10.294  50.328  1   13.597 ? 223  LYS A O   1 
ATOM   1598 C  CB  . LYS A 1 231 ? 31.223  9.701   49.612  1   16.639 ? 223  LYS A CB  1 
ATOM   1599 C  CG  . LYS A 1 231 ? 32.103  8.456   49.332  1   19.453 ? 223  LYS A CG  1 
ATOM   1600 C  CD  . LYS A 1 231 ? 33.26   8.254   50.321  1   23.045 ? 223  LYS A CD  1 
ATOM   1601 C  CE  . LYS A 1 231 ? 34.266  9.36    50.282  1   31.054 ? 223  LYS A CE  1 
ATOM   1602 N  NZ  . LYS A 1 231 ? 35.149  9.196   51.443  1   42.623 ? 223  LYS A NZ  1 
ATOM   1603 N  N   . ASP A 1 232 ? 28.645  11.722  48.579  1   14.056 ? 224  ASP A N   1 
ATOM   1604 C  CA  . ASP A 1 232 ? 27.708  12.7    49.125  1   13.711 ? 224  ASP A CA  1 
ATOM   1605 C  C   . ASP A 1 232 ? 26.29   12.15   49.252  1   14.104 ? 224  ASP A C   1 
ATOM   1606 O  O   . ASP A 1 232 ? 25.791  11.438  48.367  1   14.62  ? 224  ASP A O   1 
ATOM   1607 C  CB  . ASP A 1 232 ? 27.641  13.906  48.202  1   15.547 ? 224  ASP A CB  1 
ATOM   1608 C  CG  . ASP A 1 232 ? 29.029  14.51   48.009  1   16.172 ? 224  ASP A CG  1 
ATOM   1609 O  OD1 . ASP A 1 232 ? 29.732  14.067  47.099  1   17.569 ? 224  ASP A OD1 1 
ATOM   1610 O  OD2 . ASP A 1 232 ? 29.409  15.369  48.827  1   17.715 ? 224  ASP A OD2 1 
ATOM   1611 N  N   . VAL A 1 233 ? 25.669  12.535  50.362  1   13.288 ? 225  VAL A N   1 
ATOM   1612 C  CA  . VAL A 1 233 ? 24.283  12.207  50.656  1   12.309 ? 225  VAL A CA  1 
ATOM   1613 C  C   . VAL A 1 233 ? 23.566  13.49   51.002  1   13.167 ? 225  VAL A C   1 
ATOM   1614 O  O   . VAL A 1 233 ? 24.08   14.271  51.793  1   14.085 ? 225  VAL A O   1 
ATOM   1615 C  CB  . VAL A 1 233 ? 24.173  11.174  51.8    1   12.74  ? 225  VAL A CB  1 
ATOM   1616 C  CG1 . VAL A 1 233 ? 22.733  10.959  52.281  1   15.316 ? 225  VAL A CG1 1 
ATOM   1617 C  CG2 . VAL A 1 233 ? 24.831  9.85    51.405  1   13.912 ? 225  VAL A CG2 1 
ATOM   1618 N  N   . TYR A 1 234 ? 22.418  13.717  50.37   1   13.099 ? 226  TYR A N   1 
ATOM   1619 C  CA  . TYR A 1 234 ? 21.584  14.87   50.653  1   11.933 ? 226  TYR A CA  1 
ATOM   1620 C  C   . TYR A 1 234 ? 20.337  14.383  51.386  1   12.908 ? 226  TYR A C   1 
ATOM   1621 O  O   . TYR A 1 234 ? 19.59   13.594  50.812  1   14.403 ? 226  TYR A O   1 
ATOM   1622 C  CB  . TYR A 1 234 ? 21.24   15.548  49.32   1   12.002 ? 226  TYR A CB  1 
ATOM   1623 C  CG  . TYR A 1 234 ? 20.249  16.7    49.435  1   13.584 ? 226  TYR A CG  1 
ATOM   1624 C  CD1 . TYR A 1 234 ? 20.607  17.869  50.118  1   13.598 ? 226  TYR A CD1 1 
ATOM   1625 C  CD2 . TYR A 1 234 ? 18.96   16.602  48.922  1   13.742 ? 226  TYR A CD2 1 
ATOM   1626 C  CE1 . TYR A 1 234 ? 19.721  18.937  50.198  1   13.679 ? 226  TYR A CE1 1 
ATOM   1627 C  CE2 . TYR A 1 234 ? 18.058  17.639  49.022  1   13.313 ? 226  TYR A CE2 1 
ATOM   1628 C  CZ  . TYR A 1 234 ? 18.442  18.806  49.663  1   14.791 ? 226  TYR A CZ  1 
ATOM   1629 O  OH  . TYR A 1 234 ? 17.573  19.856  49.751  1   16.258 ? 226  TYR A OH  1 
ATOM   1630 N  N   . TYR A 1 235 ? 20.064  14.88   52.585  1   12.332 ? 227  TYR A N   1 
ATOM   1631 C  CA  . TYR A 1 235 ? 18.847  14.579  53.315  1   12.414 ? 227  TYR A CA  1 
ATOM   1632 C  C   . TYR A 1 235 ? 17.867  15.725  53.133  1   14.706 ? 227  TYR A C   1 
ATOM   1633 O  O   . TYR A 1 235 ? 18.287  16.881  53.087  1   15.433 ? 227  TYR A O   1 
ATOM   1634 C  CB  . TYR A 1 235 ? 19.22   14.451  54.804  1   12.402 ? 227  TYR A CB  1 
ATOM   1635 C  CG  . TYR A 1 235 ? 18.143  14.861  55.802  1   12.489 ? 227  TYR A CG  1 
ATOM   1636 C  CD1 . TYR A 1 235 ? 17.039  14.056  56.083  1   13.523 ? 227  TYR A CD1 1 
ATOM   1637 C  CD2 . TYR A 1 235 ? 18.251  16.079  56.48   1   13.531 ? 227  TYR A CD2 1 
ATOM   1638 C  CE1 . TYR A 1 235 ? 16.062  14.439  57.012  1   13.693 ? 227  TYR A CE1 1 
ATOM   1639 C  CE2 . TYR A 1 235 ? 17.273  16.472  57.376  1   15.056 ? 227  TYR A CE2 1 
ATOM   1640 C  CZ  . TYR A 1 235 ? 16.184  15.654  57.662  1   13.997 ? 227  TYR A CZ  1 
ATOM   1641 O  OH  . TYR A 1 235 ? 15.239  16.041  58.566  1   14.915 ? 227  TYR A OH  1 
ATOM   1642 N  N   . PHE A 1 236 ? 16.57   15.411  53.05   1   14.037 ? 228  PHE A N   1 
ATOM   1643 C  CA  . PHE A 1 236 ? 15.562  16.462  52.923  1   13.069 ? 228  PHE A CA  1 
ATOM   1644 C  C   . PHE A 1 236 ? 14.245  16.038  53.55   1   14.082 ? 228  PHE A C   1 
ATOM   1645 O  O   . PHE A 1 236 ? 13.953  14.851  53.718  1   12.931 ? 228  PHE A O   1 
ATOM   1646 C  CB  . PHE A 1 236 ? 15.304  16.814  51.445  1   13.365 ? 228  PHE A CB  1 
ATOM   1647 C  CG  . PHE A 1 236 ? 14.792  15.619  50.647  1   13.438 ? 228  PHE A CG  1 
ATOM   1648 C  CD1 . PHE A 1 236 ? 13.408  15.327  50.63   1   13.52  ? 228  PHE A CD1 1 
ATOM   1649 C  CD2 . PHE A 1 236 ? 15.688  14.785  49.954  1   12.535 ? 228  PHE A CD2 1 
ATOM   1650 C  CE1 . PHE A 1 236 ? 12.936  14.2    49.989  1   13.269 ? 228  PHE A CE1 1 
ATOM   1651 C  CE2 . PHE A 1 236 ? 15.164  13.67   49.296  1   12.654 ? 228  PHE A CE2 1 
ATOM   1652 C  CZ  . PHE A 1 236 ? 13.814  13.384  49.307  1   13.594 ? 228  PHE A CZ  1 
ATOM   1653 N  N   . GLU A 1 237 ? 13.423  17.06   53.861  1   13.038 ? 229  GLU A N   1 
ATOM   1654 C  CA  . GLU A 1 237 ? 12.015  16.869  54.122  1   13.07  ? 229  GLU A CA  1 
ATOM   1655 C  C   . GLU A 1 237 ? 11.244  17.912  53.335  1   15.944 ? 229  GLU A C   1 
ATOM   1656 O  O   . GLU A 1 237 ? 11.556  19.107  53.407  1   15.482 ? 229  GLU A O   1 
ATOM   1657 C  CB  . GLU A 1 237 ? 11.639  17.003  55.599  1   12.569 ? 229  GLU A CB  1 
ATOM   1658 C  CG  . GLU A 1 237 ? 12.474  16.105  56.511  1   12.911 ? 229  GLU A CG  1 
ATOM   1659 C  CD  . GLU A 1 237 ? 12.001  15.781  57.909  1   12.974 ? 229  GLU A CD  1 
ATOM   1660 O  OE1 . GLU A 1 237 ? 10.803  16.062  58.212  1   14.604 ? 229  GLU A OE1 1 
ATOM   1661 O  OE2 . GLU A 1 237 ? 12.798  15.172  58.662  1   13.868 ? 229  GLU A OE2 1 
ATOM   1662 N  N   . VAL A 1 238 ? 10.276  17.452  52.538  1   13.456 ? 230  VAL A N   1 
ATOM   1663 C  CA  . VAL A 1 238 ? 9.417   18.285  51.697  1   13.197 ? 230  VAL A CA  1 
ATOM   1664 C  C   . VAL A 1 238 ? 8.072   18.331  52.402  1   13.106 ? 230  VAL A C   1 
ATOM   1665 O  O   . VAL A 1 238 ? 7.445   17.313  52.679  1   14.058 ? 230  VAL A O   1 
ATOM   1666 C  CB  . VAL A 1 238 ? 9.223   17.705  50.296  1   13.255 ? 230  VAL A CB  1 
ATOM   1667 C  CG1 . VAL A 1 238 ? 8.299   18.601  49.469  1   14.331 ? 230  VAL A CG1 1 
ATOM   1668 C  CG2 . VAL A 1 238 ? 10.536  17.542  49.533  1   13.928 ? 230  VAL A CG2 1 
ATOM   1669 N  N   . ASP A 1 239 ? 7.576   19.544  52.691  1   15.046 ? 231  ASP A N   1 
ATOM   1670 C  CA  . ASP A 1 239 ? 6.337   19.646  53.433  1   15.314 ? 231  ASP A CA  1 
ATOM   1671 C  C   . ASP A 1 239 ? 5.114   19.393  52.55   1   14.854 ? 231  ASP A C   1 
ATOM   1672 O  O   . ASP A 1 239 ? 5.243   19.184  51.333  1   14.955 ? 231  ASP A O   1 
ATOM   1673 C  CB  . ASP A 1 239 ? 6.297   20.993  54.164  1   17.353 ? 231  ASP A CB  1 
ATOM   1674 C  CG  . ASP A 1 239 ? 5.92    22.21   53.335  1   18.097 ? 231  ASP A CG  1 
ATOM   1675 O  OD1 . ASP A 1 239 ? 5.596   22.123  52.131  1   17.712 ? 231  ASP A OD1 1 
ATOM   1676 O  OD2 . ASP A 1 239 ? 5.933   23.316  53.993  1   22.201 ? 231  ASP A OD2 1 
ATOM   1677 N  N   . PRO A 1 240 ? 3.892   19.302  53.15   1   15.117 ? 232  PRO A N   1 
ATOM   1678 C  CA  . PRO A 1 240 ? 2.699   19.023  52.335  1   15.45  ? 232  PRO A CA  1 
ATOM   1679 C  C   . PRO A 1 240 ? 2.358   20.015  51.253  1   15.398 ? 232  PRO A C   1 
ATOM   1680 O  O   . PRO A 1 240 ? 1.502   19.739  50.407  1   17.045 ? 232  PRO A O   1 
ATOM   1681 C  CB  . PRO A 1 240 ? 1.586   18.968  53.393  1   16.361 ? 232  PRO A CB  1 
ATOM   1682 C  CG  . PRO A 1 240 ? 2.311   18.5    54.65   1   16.376 ? 232  PRO A CG  1 
ATOM   1683 C  CD  . PRO A 1 240 ? 3.587   19.319  54.587  1   15.896 ? 232  PRO A CD  1 
ATOM   1684 N  N   . SER A 1 241 ? 3.024   21.177  51.277  1   16.377 ? 233  SER A N   1 
ATOM   1685 C  CA  . SER A 1 241 ? 2.809   22.163  50.222  1   17.759 ? 233  SER A CA  1 
ATOM   1686 C  C   . SER A 1 241 ? 3.845   22.069  49.107  1   18.013 ? 233  SER A C   1 
ATOM   1687 O  O   . SER A 1 241 ? 3.81    22.852  48.154  1   20.039 ? 233  SER A O   1 
ATOM   1688 C  CB  . SER A 1 241 ? 2.71    23.609  50.807  1   19.293 ? 233  SER A CB  1 
ATOM   1689 O  OG  . SER A 1 241 ? 4.008   24.059  51.18   1   24.19  ? 233  SER A OG  1 
ATOM   1690 N  N   . GLY A 1 242 ? 4.852   21.171  49.244  1   15.652 ? 234  GLY A N   1 
ATOM   1691 C  CA  . GLY A 1 242 ? 5.847   20.999  48.217  1   16.012 ? 234  GLY A CA  1 
ATOM   1692 C  C   . GLY A 1 242 ? 7.162   21.727  48.47   1   16.416 ? 234  GLY A C   1 
ATOM   1693 O  O   . GLY A 1 242 ? 7.991   21.73   47.557  1   18.96  ? 234  GLY A O   1 
ATOM   1694 N  N   . LYS A 1 243 ? 7.318   22.334  49.647  1   17.143 ? 235  LYS A N   1 
ATOM   1695 C  CA  . LYS A 1 243 ? 8.522   23.131  49.943  1   19.635 ? 235  LYS A CA  1 
ATOM   1696 C  C   . LYS A 1 243 ? 9.532   22.287  50.732  1   16.27  ? 235  LYS A C   1 
ATOM   1697 O  O   . LYS A 1 243 ? 9.157   21.627  51.677  1   16.388 ? 235  LYS A O   1 
ATOM   1698 C  CB  . LYS A 1 243 ? 8.058   24.336  50.774  1   23.834 ? 235  LYS A CB  1 
ATOM   1699 C  CG  . LYS A 1 243 ? 9.159   25.282  51.21   1   30.815 ? 235  LYS A CG  1 
ATOM   1700 C  CD  . LYS A 1 243 ? 8.739   26.465  52.071  1   34.51  ? 235  LYS A CD  1 
ATOM   1701 C  CE  . LYS A 1 243 ? 9.948   27.178  52.62   1   47.152 ? 235  LYS A CE  1 
ATOM   1702 N  NZ  . LYS A 1 243 ? 11.001  27.558  51.664  1   49.512 ? 235  LYS A NZ  1 
ATOM   1703 N  N   . VAL A 1 244 ? 10.827  22.398  50.381  1   15.501 ? 236  VAL A N   1 
ATOM   1704 C  CA  . VAL A 1 244 ? 11.886  21.758  51.162  1   17.07  ? 236  VAL A CA  1 
ATOM   1705 C  C   . VAL A 1 244 ? 12.046  22.584  52.431  1   18.152 ? 236  VAL A C   1 
ATOM   1706 O  O   . VAL A 1 244 ? 12.471  23.748  52.335  1   21.012 ? 236  VAL A O   1 
ATOM   1707 C  CB  . VAL A 1 244 ? 13.22   21.607  50.418  1   17.907 ? 236  VAL A CB  1 
ATOM   1708 C  CG1 . VAL A 1 244 ? 14.333  21.07   51.346  1   18.567 ? 236  VAL A CG1 1 
ATOM   1709 C  CG2 . VAL A 1 244 ? 13.056  20.749  49.171  1   18.243 ? 236  VAL A CG2 1 
ATOM   1710 N  N   . VAL A 1 245 ? 11.702  21.998  53.565  1   16.412 ? 237  VAL A N   1 
ATOM   1711 C  CA  . VAL A 1 245 ? 11.701  22.705  54.84   1   17.696 ? 237  VAL A CA  1 
ATOM   1712 C  C   . VAL A 1 245 ? 12.87   22.305  55.721  1   17.394 ? 237  VAL A C   1 
ATOM   1713 O  O   . VAL A 1 245 ? 13.155  23.026  56.686  1   18.651 ? 237  VAL A O   1 
ATOM   1714 C  CB  . VAL A 1 245 ? 10.358  22.61   55.592  1   18.564 ? 237  VAL A CB  1 
ATOM   1715 C  CG1 . VAL A 1 245 ? 9.252   23.329  54.817  1   19.16  ? 237  VAL A CG1 1 
ATOM   1716 C  CG2 . VAL A 1 245 ? 9.985   21.152  55.917  1   16.269 ? 237  VAL A CG2 1 
ATOM   1717 N  N   . ARG A 1 246 ? 13.52   21.156  55.449  1   14.965 ? 238  ARG A N   1 
ATOM   1718 C  CA  . ARG A 1 246 ? 14.681  20.716  56.204  1   15.238 ? 238  ARG A CA  1 
ATOM   1719 C  C   . ARG A 1 246 ? 15.599  20.026  55.209  1   16.048 ? 238  ARG A C   1 
ATOM   1720 O  O   . ARG A 1 246 ? 15.13   19.317  54.323  1   15.375 ? 238  ARG A O   1 
ATOM   1721 C  CB  . ARG A 1 246 ? 14.36   19.637  57.244  1   15.38  ? 238  ARG A CB  1 
ATOM   1722 C  CG  . ARG A 1 246 ? 13.497  20.141  58.41   1   16.145 ? 238  ARG A CG  1 
ATOM   1723 C  CD  . ARG A 1 246 ? 12.915  18.933  59.142  1   17.631 ? 238  ARG A CD  1 
ATOM   1724 N  NE  . ARG A 1 246 ? 12.491  19.293  60.499  1   22.443 ? 238  ARG A NE  1 
ATOM   1725 C  CZ  . ARG A 1 246 ? 11.837  18.487  61.331  1   25.339 ? 238  ARG A CZ  1 
ATOM   1726 N  NH1 . ARG A 1 246 ? 11.162  17.399  60.92   1   22.219 ? 238  ARG A NH1 1 
ATOM   1727 N  NH2 . ARG A 1 246 ? 11.825  18.836  62.613  1   27.706 ? 238  ARG A NH2 1 
ATOM   1728 N  N   . ASP A 1 247 ? 16.91   20.276  55.307  1   14.298 ? 239  ASP A N   1 
ATOM   1729 C  CA  . ASP A 1 247 ? 17.876  19.555  54.488  1   14.994 ? 239  ASP A CA  1 
ATOM   1730 C  C   . ASP A 1 247 ? 19.225  19.556  55.175  1   15.295 ? 239  ASP A C   1 
ATOM   1731 O  O   . ASP A 1 247 ? 19.439  20.25   56.19   1   17.563 ? 239  ASP A O   1 
ATOM   1732 C  CB  . ASP A 1 247 ? 17.857  19.986  53.028  1   17.292 ? 239  ASP A CB  1 
ATOM   1733 C  CG  . ASP A 1 247 ? 18.423  21.371  52.714  1   17.936 ? 239  ASP A CG  1 
ATOM   1734 O  OD1 . ASP A 1 247 ? 18.823  22.053  53.681  1   20.118 ? 239  ASP A OD1 1 
ATOM   1735 O  OD2 . ASP A 1 247 ? 18.41   21.72   51.529  1   18.145 ? 239  ASP A OD2 1 
ATOM   1736 N  N   . LEU A 1 248 ? 20.124  18.752  54.616  1   14.918 ? 240  LEU A N   1 
ATOM   1737 C  CA  . LEU A 1 248 ? 21.487  18.617  55.109  1   14.744 ? 240  LEU A CA  1 
ATOM   1738 C  C   . LEU A 1 248 ? 22.317  17.884  54.067  1   16.449 ? 240  LEU A C   1 
ATOM   1739 O  O   . LEU A 1 248 ? 21.867  16.85   53.547  1   15.966 ? 240  LEU A O   1 
ATOM   1740 C  CB  . LEU A 1 248 ? 21.552  17.862  56.437  1   15.564 ? 240  LEU A CB  1 
ATOM   1741 C  CG  . LEU A 1 248 ? 22.938  17.747  57.073  1   18.08  ? 240  LEU A CG  1 
ATOM   1742 C  CD1 . LEU A 1 248 ? 23.342  19.116  57.622  1   20.849 ? 240  LEU A CD1 1 
ATOM   1743 C  CD2 . LEU A 1 248 ? 22.869  16.789  58.264  1   18.519 ? 240  LEU A CD2 1 
ATOM   1744 N  N   . TRP A 1 249 ? 23.545  18.349  53.82   1   15.171 ? 241  TRP A N   1 
ATOM   1745 C  CA  . TRP A 1 249 ? 24.53   17.602  53.051  1   13.506 ? 241  TRP A CA  1 
ATOM   1746 C  C   . TRP A 1 249 ? 25.451  16.867  54.021  1   14.944 ? 241  TRP A C   1 
ATOM   1747 O  O   . TRP A 1 249 ? 25.922  17.417  55.022  1   18.433 ? 241  TRP A O   1 
ATOM   1748 C  CB  . TRP A 1 249 ? 25.343  18.518  52.126  1   16.472 ? 241  TRP A CB  1 
ATOM   1749 C  CG  . TRP A 1 249 ? 24.519  18.983  50.954  1   15.007 ? 241  TRP A CG  1 
ATOM   1750 C  CD1 . TRP A 1 249 ? 23.649  20.037  50.894  1   16.261 ? 241  TRP A CD1 1 
ATOM   1751 C  CD2 . TRP A 1 249 ? 24.423  18.327  49.674  1   16.397 ? 241  TRP A CD2 1 
ATOM   1752 N  NE1 . TRP A 1 249 ? 23.097  20.138  49.65   1   18.911 ? 241  TRP A NE1 1 
ATOM   1753 C  CE2 . TRP A 1 249 ? 23.546  19.103  48.883  1   17.651 ? 241  TRP A CE2 1 
ATOM   1754 C  CE3 . TRP A 1 249 ? 25.035  17.204  49.125  1   18.575 ? 241  TRP A CE3 1 
ATOM   1755 C  CZ2 . TRP A 1 249 ? 23.219  18.755  47.562  1   20.744 ? 241  TRP A CZ2 1 
ATOM   1756 C  CZ3 . TRP A 1 249 ? 24.716  16.852  47.824  1   21.101 ? 241  TRP A CZ3 1 
ATOM   1757 C  CH2 . TRP A 1 249 ? 23.881  17.661  47.056  1   20.641 ? 241  TRP A CH2 1 
ATOM   1758 N  N   . LEU A 1 250 ? 25.756  15.62   53.723  1   15.258 ? 242  LEU A N   1 
ATOM   1759 C  CA  . LEU A 1 250 ? 26.612  14.747  54.516  1   14.633 ? 242  LEU A CA  1 
ATOM   1760 C  C   . LEU A 1 250 ? 27.258  13.741  53.574  1   14     ? 242  LEU A C   1 
ATOM   1761 O  O   . LEU A 1 250 ? 27.195  13.875  52.338  1   14.728 ? 242  LEU A O   1 
ATOM   1762 C  CB  . LEU A 1 250 ? 25.829  14.038  55.635  1   15.987 ? 242  LEU A CB  1 
ATOM   1763 C  CG  . LEU A 1 250 ? 24.635  13.186  55.154  1   17.137 ? 242  LEU A CG  1 
ATOM   1764 C  CD1 . LEU A 1 250 ? 24.648  11.828  55.89   1   16.804 ? 242  LEU A CD1 1 
ATOM   1765 C  CD2 . LEU A 1 250 ? 23.282  13.853  55.321  1   17.068 ? 242  LEU A CD2 1 
ATOM   1766 N  N   . GLU A 1 251 ? 27.982  12.768  54.141  1   16.263 ? 243  GLU A N   1 
ATOM   1767 C  CA  . GLU A 1 251 ? 28.628  11.746  53.313  1   15.484 ? 243  GLU A CA  1 
ATOM   1768 C  C   . GLU A 1 251 ? 28.376  10.392  53.957  1   15.475 ? 243  GLU A C   1 
ATOM   1769 O  O   . GLU A 1 251 ? 28.21   10.293  55.175  1   16.656 ? 243  GLU A O   1 
ATOM   1770 C  CB  . GLU A 1 251 ? 30.148  11.936  53.229  1   18.086 ? 243  GLU A CB  1 
ATOM   1771 C  CG  . GLU A 1 251 ? 30.556  13.06   52.274  1   22.188 ? 243  GLU A CG  1 
ATOM   1772 C  CD  . GLU A 1 251 ? 32.056  13.365  52.285  1   30.693 ? 243  GLU A CD  1 
ATOM   1773 O  OE1 . GLU A 1 251 ? 32.543  13.863  53.316  1   33.632 ? 243  GLU A OE1 1 
ATOM   1774 O  OE2 . GLU A 1 251 ? 32.72   13.093  51.276  1   34.524 ? 243  GLU A OE2 1 
ATOM   1775 N  N   . ALA A 1 252 ? 28.374  9.344   53.122  1   14.487 ? 244  ALA A N   1 
ATOM   1776 C  CA  . ALA A 1 252 ? 28.398  7.973   53.627  1   14.612 ? 244  ALA A CA  1 
ATOM   1777 C  C   . ALA A 1 252 ? 29.849  7.552   53.894  1   16.097 ? 244  ALA A C   1 
ATOM   1778 O  O   . ALA A 1 252 ? 30.759  8.117   53.279  1   16.385 ? 244  ALA A O   1 
ATOM   1779 C  CB  . ALA A 1 252 ? 27.722  7.048   52.603  1   15.181 ? 244  ALA A CB  1 
ATOM   1780 N  N   . PRO A 1 253 ? 30.119  6.555   54.753  1   15.052 ? 245  PRO A N   1 
ATOM   1781 C  CA  . PRO A 1 253 ? 31.501  6.126   55.008  1   15.922 ? 245  PRO A CA  1 
ATOM   1782 C  C   . PRO A 1 253 ? 32.263  5.561   53.827  1   17.866 ? 245  PRO A C   1 
ATOM   1783 O  O   . PRO A 1 253 ? 33.505  5.63    53.79   1   18.369 ? 245  PRO A O   1 
ATOM   1784 C  CB  . PRO A 1 253 ? 31.38   5.176   56.192  1   16.945 ? 245  PRO A CB  1 
ATOM   1785 C  CG  . PRO A 1 253 ? 29.941  4.655   56.116  1   15.832 ? 245  PRO A CG  1 
ATOM   1786 C  CD  . PRO A 1 253 ? 29.158  5.849   55.629  1   15.211 ? 245  PRO A CD  1 
ATOM   1787 N  N   . TRP A 1 254 ? 31.519  5.006   52.873  1   15.271 ? 246  TRP A N   1 
ATOM   1788 C  CA  . TRP A 1 254 ? 32.012  4.543   51.59   1   14.402 ? 246  TRP A CA  1 
ATOM   1789 C  C   . TRP A 1 254 ? 30.896  4.825   50.581  1   14.758 ? 246  TRP A C   1 
ATOM   1790 O  O   . TRP A 1 254 ? 29.779  5.16    51.033  1   15.127 ? 246  TRP A O   1 
ATOM   1791 C  CB  . TRP A 1 254 ? 32.489  3.077   51.641  1   16.499 ? 246  TRP A CB  1 
ATOM   1792 C  CG  . TRP A 1 254 ? 31.398  2.021   51.6    1   14.425 ? 246  TRP A CG  1 
ATOM   1793 C  CD1 . TRP A 1 254 ? 30.89   1.419   50.478  1   15.718 ? 246  TRP A CD1 1 
ATOM   1794 C  CD2 . TRP A 1 254 ? 30.747  1.409   52.732  1   13.845 ? 246  TRP A CD2 1 
ATOM   1795 N  NE1 . TRP A 1 254 ? 29.951  0.484   50.865  1   15.321 ? 246  TRP A NE1 1 
ATOM   1796 C  CE2 . TRP A 1 254 ? 29.842  0.456   52.229  1   14.41  ? 246  TRP A CE2 1 
ATOM   1797 C  CE3 . TRP A 1 254 ? 30.843  1.586   54.129  1   14.754 ? 246  TRP A CE3 1 
ATOM   1798 C  CZ2 . TRP A 1 254 ? 29.016  -0.312  53.056  1   14.903 ? 246  TRP A CZ2 1 
ATOM   1799 C  CZ3 . TRP A 1 254 ? 30.055  0.786   54.954  1   15.947 ? 246  TRP A CZ3 1 
ATOM   1800 C  CH2 . TRP A 1 254 ? 29.136  -0.133  54.418  1   15.965 ? 246  TRP A CH2 1 
ATOM   1801 N  N   . CYS A 1 255 ? 31.185  4.711   49.269  1   16.959 ? 247  CYS A N   1 
ATOM   1802 C  CA  . CYS A 1 255 ? 30.087  4.892   48.321  1   15.651 ? 247  CYS A CA  1 
ATOM   1803 C  C   . CYS A 1 255 ? 29.319  3.579   48.275  1   14.697 ? 247  CYS A C   1 
ATOM   1804 O  O   . CYS A 1 255 ? 29.702  2.631   47.602  1   13.963 ? 247  CYS A O   1 
ATOM   1805 C  CB  . CYS A 1 255 ? 30.512  5.325   46.929  1   15.594 ? 247  CYS A CB  1 
ATOM   1806 S  SG  . CYS A 1 255 ? 29.078  5.687   45.877  1   17.91  ? 247  CYS A SG  1 
ATOM   1807 N  N   . ALA A 1 256 ? 28.243  3.564   49.075  1   15.146 ? 248  ALA A N   1 
ATOM   1808 C  CA  . ALA A 1 256 ? 27.456  2.387   49.376  1   12.537 ? 248  ALA A CA  1 
ATOM   1809 C  C   . ALA A 1 256 ? 26.102  2.458   48.68   1   14.629 ? 248  ALA A C   1 
ATOM   1810 O  O   . ALA A 1 256 ? 25.594  3.551   48.353  1   14.931 ? 248  ALA A O   1 
ATOM   1811 C  CB  . ALA A 1 256 ? 27.271  2.353   50.881  1   16.028 ? 248  ALA A CB  1 
ATOM   1812 N  N   . PHE A 1 257 ? 25.475  1.28    48.543  1   12.762 ? 249  PHE A N   1 
ATOM   1813 C  CA  . PHE A 1 257 ? 24.16   1.187   47.904  1   12.291 ? 249  PHE A CA  1 
ATOM   1814 C  C   . PHE A 1 257 ? 23.147  1.387   49.037  1   12.5   ? 249  PHE A C   1 
ATOM   1815 O  O   . PHE A 1 257 ? 22.852  0.459   49.831  1   13.309 ? 249  PHE A O   1 
ATOM   1816 C  CB  . PHE A 1 257 ? 24.137  -0.209  47.27   1   12.734 ? 249  PHE A CB  1 
ATOM   1817 C  CG  . PHE A 1 257 ? 23.015  -0.52   46.299  1   13.732 ? 249  PHE A CG  1 
ATOM   1818 C  CD1 . PHE A 1 257 ? 21.749  0.089   46.339  1   13.069 ? 249  PHE A CD1 1 
ATOM   1819 C  CD2 . PHE A 1 257 ? 23.258  -1.478  45.306  1   13.727 ? 249  PHE A CD2 1 
ATOM   1820 C  CE1 . PHE A 1 257 ? 20.777  -0.235  45.367  1   12.911 ? 249  PHE A CE1 1 
ATOM   1821 C  CE2 . PHE A 1 257 ? 22.269  -1.817  44.391  1   13.323 ? 249  PHE A CE2 1 
ATOM   1822 C  CZ  . PHE A 1 257 ? 21.022  -1.193  44.403  1   12.855 ? 249  PHE A CZ  1 
ATOM   1823 N  N   . ILE A 1 258 ? 22.611  2.61    49.123  1   12.001 ? 250  ILE A N   1 
ATOM   1824 C  CA  . ILE A 1 258 ? 21.684  2.991   50.2    1   12.04  ? 250  ILE A CA  1 
ATOM   1825 C  C   . ILE A 1 258 ? 20.265  2.947   49.631  1   12.283 ? 250  ILE A C   1 
ATOM   1826 O  O   . ILE A 1 258 ? 19.724  3.97    49.234  1   11.968 ? 250  ILE A O   1 
ATOM   1827 C  CB  . ILE A 1 258 ? 22.032  4.377   50.795  1   11.015 ? 250  ILE A CB  1 
ATOM   1828 C  CG1 . ILE A 1 258 ? 23.533  4.491   51.093  1   12.53  ? 250  ILE A CG1 1 
ATOM   1829 C  CG2 . ILE A 1 258 ? 21.175  4.567   52.054  1   13.288 ? 250  ILE A CG2 1 
ATOM   1830 C  CD1 . ILE A 1 258 ? 23.931  5.812   51.744  1   12.443 ? 250  ILE A CD1 1 
ATOM   1831 N  N   . HIS A 1 259 ? 19.705  1.742   49.577  1   11.162 ? 251  HIS A N   1 
ATOM   1832 C  CA  . HIS A 1 259 ? 18.428  1.563   48.898  1   11.657 ? 251  HIS A CA  1 
ATOM   1833 C  C   . HIS A 1 259 ? 17.273  2.143   49.713  1   11.872 ? 251  HIS A C   1 
ATOM   1834 O  O   . HIS A 1 259 ? 16.352  2.711   49.112  1   12.57  ? 251  HIS A O   1 
ATOM   1835 C  CB  . HIS A 1 259 ? 18.237  0.043   48.653  1   12.662 ? 251  HIS A CB  1 
ATOM   1836 C  CG  . HIS A 1 259 ? 17      -0.204  47.851  1   11.793 ? 251  HIS A CG  1 
ATOM   1837 N  ND1 . HIS A 1 259 ? 16.805  0.278   46.571  1   13.412 ? 251  HIS A ND1 1 
ATOM   1838 C  CD2 . HIS A 1 259 ? 15.845  -0.791  48.218  1   11.48  ? 251  HIS A CD2 1 
ATOM   1839 C  CE1 . HIS A 1 259 ? 15.607  -0.079  46.131  1   13.036 ? 251  HIS A CE1 1 
ATOM   1840 N  NE2 . HIS A 1 259 ? 14.987  -0.714  47.118  1   11.37  ? 251  HIS A NE2 1 
ATOM   1841 N  N   . ASP A 1 260 ? 17.246  1.833   51.003  1   12.068 ? 252  ASP A N   1 
ATOM   1842 C  CA  . ASP A 1 260 ? 16.064  2.106   51.817  1   11.195 ? 252  ASP A CA  1 
ATOM   1843 C  C   . ASP A 1 260 ? 16.516  2.761   53.116  1   11.256 ? 252  ASP A C   1 
ATOM   1844 O  O   . ASP A 1 260 ? 17.704  2.949   53.401  1   12.371 ? 252  ASP A O   1 
ATOM   1845 C  CB  . ASP A 1 260 ? 15.248  0.829   51.935  1   13.147 ? 252  ASP A CB  1 
ATOM   1846 C  CG  . ASP A 1 260 ? 13.797  0.939   52.397  1   13.196 ? 252  ASP A CG  1 
ATOM   1847 O  OD1 . ASP A 1 260 ? 13.263  2.054   52.594  1   11.786 ? 252  ASP A OD1 1 
ATOM   1848 O  OD2 . ASP A 1 260 ? 13.197  -0.139  52.599  1   12.96  ? 252  ASP A OD2 1 
ATOM   1849 N  N   . CYS A 1 261 ? 15.544  3.066   53.974  1   12.119 ? 253  CYS A N   1 
ATOM   1850 C  CA  . CYS A 1 261 ? 15.734  3.849   55.174  1   11.584 ? 253  CYS A CA  1 
ATOM   1851 C  C   . CYS A 1 261 ? 14.569  3.542   56.113  1   10.566 ? 253  CYS A C   1 
ATOM   1852 O  O   . CYS A 1 261 ? 13.593  2.9     55.727  1   11.253 ? 253  CYS A O   1 
ATOM   1853 C  CB  . CYS A 1 261 ? 15.849  5.356   54.86   1   11.339 ? 253  CYS A CB  1 
ATOM   1854 S  SG  . CYS A 1 261 ? 14.338  6.079   54.162  1   13.185 ? 253  CYS A SG  1 
ATOM   1855 N  N   . ALA A 1 262 ? 14.648  4.092   57.326  1   12.738 ? 254  ALA A N   1 
ATOM   1856 C  CA  . ALA A 1 262 ? 13.513  4.005   58.237  1   11.182 ? 254  ALA A CA  1 
ATOM   1857 C  C   . ALA A 1 262 ? 13.318  5.381   58.86   1   12.35  ? 254  ALA A C   1 
ATOM   1858 O  O   . ALA A 1 262 ? 14.286  6.045   59.237  1   12.787 ? 254  ALA A O   1 
ATOM   1859 C  CB  . ALA A 1 262 ? 13.794  3.015   59.362  1   13.027 ? 254  ALA A CB  1 
ATOM   1860 N  N   . LEU A 1 263 ? 12.042  5.763   59.016  1   12.486 ? 255  LEU A N   1 
ATOM   1861 C  CA  . LEU A 1 263 ? 11.646  7.044   59.604  1   12.79  ? 255  LEU A CA  1 
ATOM   1862 C  C   . LEU A 1 263 ? 11.115  6.805   61.012  1   14.106 ? 255  LEU A C   1 
ATOM   1863 O  O   . LEU A 1 263 ? 10.251  5.955   61.239  1   14.491 ? 255  LEU A O   1 
ATOM   1864 C  CB  . LEU A 1 263 ? 10.517  7.682   58.779  1   13.45  ? 255  LEU A CB  1 
ATOM   1865 C  CG  . LEU A 1 263 ? 10.135  9.093   59.275  1   12.666 ? 255  LEU A CG  1 
ATOM   1866 C  CD1 . LEU A 1 263 ? 11.254  10.051  59.031  1   13.88  ? 255  LEU A CD1 1 
ATOM   1867 C  CD2 . LEU A 1 263 ? 8.89    9.48    58.529  1   14.4   ? 255  LEU A CD2 1 
ATOM   1868 N  N   . THR A 1 264 ? 11.63   7.633   61.954  1   14.739 ? 256  THR A N   1 
ATOM   1869 C  CA  . THR A 1 264 ? 11.195  7.59    63.346  1   14.79  ? 256  THR A CA  1 
ATOM   1870 C  C   . THR A 1 264 ? 10.811  9.01    63.746  1   13.801 ? 256  THR A C   1 
ATOM   1871 O  O   . THR A 1 264 ? 11.056  9.957   62.962  1   14.726 ? 256  THR A O   1 
ATOM   1872 C  CB  . THR A 1 264 ? 12.252  6.999   64.295  1   16.595 ? 256  THR A CB  1 
ATOM   1873 O  OG1 . THR A 1 264 ? 13.263  7.976   64.541  1   14.995 ? 256  THR A OG1 1 
ATOM   1874 C  CG2 . THR A 1 264 ? 12.896  5.747   63.729  1   14.966 ? 256  THR A CG2 1 
ATOM   1875 N  N   . PRO A 1 265 ? 10.244  9.256   64.958  1   14.705 ? 257  PRO A N   1 
ATOM   1876 C  CA  . PRO A 1 265 ? 9.888   10.642  65.255  1   16.929 ? 257  PRO A CA  1 
ATOM   1877 C  C   . PRO A 1 265 ? 11.029  11.64   65.161  1   15.503 ? 257  PRO A C   1 
ATOM   1878 O  O   . PRO A 1 265 ? 10.85   12.784  64.699  1   18.66  ? 257  PRO A O   1 
ATOM   1879 C  CB  . PRO A 1 265 ? 9.294   10.532  66.666  1   16.493 ? 257  PRO A CB  1 
ATOM   1880 C  CG  . PRO A 1 265 ? 8.729   9.167   66.724  1   15.745 ? 257  PRO A CG  1 
ATOM   1881 C  CD  . PRO A 1 265 ? 9.733   8.273   65.938  1   15.204 ? 257  PRO A CD  1 
ATOM   1882 N  N   . ASN A 1 266 ? 12.235  11.198  65.564  1   15.976 ? 258  ASN A N   1 
ATOM   1883 C  CA  . ASN A 1 266 ? 13.364  12.115  65.676  1   16.503 ? 258  ASN A CA  1 
ATOM   1884 C  C   . ASN A 1 266 ? 14.518  11.826  64.721  1   17.151 ? 258  ASN A C   1 
ATOM   1885 O  O   . ASN A 1 266 ? 15.513  12.577  64.725  1   16.839 ? 258  ASN A O   1 
ATOM   1886 C  CB  . ASN A 1 266 ? 13.88   12.175  67.119  1   17.814 ? 258  ASN A CB  1 
ATOM   1887 C  CG  . ASN A 1 266 ? 12.783  12.658  68.036  1   20.713 ? 258  ASN A CG  1 
ATOM   1888 O  OD1 . ASN A 1 266 ? 12.287  13.787  67.865  1   21.494 ? 258  ASN A OD1 1 
ATOM   1889 N  ND2 . ASN A 1 266 ? 12.319  11.769  68.904  1   18.042 ? 258  ASN A ND2 1 
ATOM   1890 N  N   . TYR A 1 267 ? 14.374  10.769  63.884  1   14.592 ? 259  TYR A N   1 
ATOM   1891 C  CA  . TYR A 1 267 ? 15.497  10.368  63.034  1   14.204 ? 259  TYR A CA  1 
ATOM   1892 C  C   . TYR A 1 267 ? 15.022  9.909   61.667  1   13.92  ? 259  TYR A C   1 
ATOM   1893 O  O   . TYR A 1 267 ? 13.924  9.389   61.511  1   15.639 ? 259  TYR A O   1 
ATOM   1894 C  CB  . TYR A 1 267 ? 16.243  9.168   63.632  1   15.532 ? 259  TYR A CB  1 
ATOM   1895 C  CG  . TYR A 1 267 ? 17.024  9.48    64.891  1   17.35  ? 259  TYR A CG  1 
ATOM   1896 C  CD1 . TYR A 1 267 ? 18.331  9.941   64.829  1   16.099 ? 259  TYR A CD1 1 
ATOM   1897 C  CD2 . TYR A 1 267 ? 16.45   9.272   66.146  1   16.052 ? 259  TYR A CD2 1 
ATOM   1898 C  CE1 . TYR A 1 267 ? 19.083  10.191  65.98   1   16.753 ? 259  TYR A CE1 1 
ATOM   1899 C  CE2 . TYR A 1 267 ? 17.183  9.525   67.303  1   18.188 ? 259  TYR A CE2 1 
ATOM   1900 C  CZ  . TYR A 1 267 ? 18.485  9.996   67.21   1   19.708 ? 259  TYR A CZ  1 
ATOM   1901 O  OH  . TYR A 1 267 ? 19.233  10.24   68.348  1   22.054 ? 259  TYR A OH  1 
ATOM   1902 N  N   . LEU A 1 268 ? 15.904  10.133  60.69   1   13.325 ? 260  LEU A N   1 
ATOM   1903 C  CA  . LEU A 1 268 ? 15.863  9.346   59.46   1   12.748 ? 260  LEU A CA  1 
ATOM   1904 C  C   . LEU A 1 268 ? 17.103  8.46    59.499  1   14.421 ? 260  LEU A C   1 
ATOM   1905 O  O   . LEU A 1 268 ? 18.196  8.938   59.792  1   14.324 ? 260  LEU A O   1 
ATOM   1906 C  CB  . LEU A 1 268 ? 15.868  10.255  58.223  1   13.025 ? 260  LEU A CB  1 
ATOM   1907 C  CG  . LEU A 1 268 ? 15.879  9.449   56.91   1   12.821 ? 260  LEU A CG  1 
ATOM   1908 C  CD1 . LEU A 1 268 ? 14.577  8.725   56.701  1   14.22  ? 260  LEU A CD1 1 
ATOM   1909 C  CD2 . LEU A 1 268 ? 16.135  10.357  55.686  1   12.797 ? 260  LEU A CD2 1 
ATOM   1910 N  N   . VAL A 1 269 ? 16.888  7.158   59.308  1   12.484 ? 261  VAL A N   1 
ATOM   1911 C  CA  . VAL A 1 269 ? 17.989  6.195   59.47   1   12.133 ? 261  VAL A CA  1 
ATOM   1912 C  C   . VAL A 1 269 ? 18.222  5.534   58.109  1   12.172 ? 261  VAL A C   1 
ATOM   1913 O  O   . VAL A 1 269 ? 17.369  4.855   57.596  1   12.962 ? 261  VAL A O   1 
ATOM   1914 C  CB  . VAL A 1 269 ? 17.717  5.131   60.545  1   13.849 ? 261  VAL A CB  1 
ATOM   1915 C  CG1 . VAL A 1 269 ? 19.013  4.337   60.797  1   13.622 ? 261  VAL A CG1 1 
ATOM   1916 C  CG2 . VAL A 1 269 ? 17.204  5.767   61.844  1   13.982 ? 261  VAL A CG2 1 
ATOM   1917 N  N   . LEU A 1 270 ? 19.406  5.762   57.53   1   11.316 ? 262  LEU A N   1 
ATOM   1918 C  CA  . LEU A 1 270 ? 19.753  5.209   56.225  1   12.668 ? 262  LEU A CA  1 
ATOM   1919 C  C   . LEU A 1 270 ? 20.335  3.813   56.41   1   12.614 ? 262  LEU A C   1 
ATOM   1920 O  O   . LEU A 1 270 ? 21.138  3.604   57.326  1   12.508 ? 262  LEU A O   1 
ATOM   1921 C  CB  . LEU A 1 270 ? 20.789  6.08    55.506  1   13.445 ? 262  LEU A CB  1 
ATOM   1922 C  CG  . LEU A 1 270 ? 20.432  7.572   55.415  1   15.587 ? 262  LEU A CG  1 
ATOM   1923 C  CD1 . LEU A 1 270 ? 21.393  8.282   54.478  1   13.998 ? 262  LEU A CD1 1 
ATOM   1924 C  CD2 . LEU A 1 270 ? 19.012  7.818   54.945  1   15.496 ? 262  LEU A CD2 1 
ATOM   1925 N  N   . MET A 1 271 ? 20.011  2.894   55.482  1   12.184 ? 263  MET A N   1 
ATOM   1926 C  CA  . MET A 1 271 ? 20.401  1.48    55.608  1   12.1   ? 263  MET A CA  1 
ATOM   1927 C  C   . MET A 1 271 ? 21.403  1.194   54.475  1   12.398 ? 263  MET A C   1 
ATOM   1928 O  O   . MET A 1 271 ? 21.031  1.282   53.292  1   12.645 ? 263  MET A O   1 
ATOM   1929 C  CB  . MET A 1 271 ? 19.127  0.607   55.539  1   12.149 ? 263  MET A CB  1 
ATOM   1930 C  CG  . MET A 1 271 ? 19.415  -0.892  55.717  1   12.248 ? 263  MET A CG  1 
ATOM   1931 S  SD  . MET A 1 271 ? 17.898  -1.82   55.987  1   14.1   ? 263  MET A SD  1 
ATOM   1932 C  CE  . MET A 1 271 ? 17.067  -1.592  54.416  1   13.99  ? 263  MET A CE  1 
ATOM   1933 N  N   . LEU A 1 272 ? 22.664  0.903   54.812  1   11.525 ? 264  LEU A N   1 
ATOM   1934 C  CA  . LEU A 1 272 ? 23.692  0.664   53.783  1   11.52  ? 264  LEU A CA  1 
ATOM   1935 C  C   . LEU A 1 272 ? 23.876  -0.806  53.489  1   13.242 ? 264  LEU A C   1 
ATOM   1936 O  O   . LEU A 1 272 ? 24.204  -1.593  54.386  1   13.333 ? 264  LEU A O   1 
ATOM   1937 C  CB  . LEU A 1 272 ? 25.047  1.235   54.212  1   11.499 ? 264  LEU A CB  1 
ATOM   1938 C  CG  . LEU A 1 272 ? 25.228  2.746   54.039  1   12.43  ? 264  LEU A CG  1 
ATOM   1939 C  CD1 . LEU A 1 272 ? 24.229  3.56    54.887  1   13.561 ? 264  LEU A CD1 1 
ATOM   1940 C  CD2 . LEU A 1 272 ? 26.68   3.149   54.448  1   13.151 ? 264  LEU A CD2 1 
ATOM   1941 N  N   . TRP A 1 273 ? 23.635  -1.186  52.232  1   12.839 ? 265  TRP A N   1 
ATOM   1942 C  CA  . TRP A 1 273 ? 23.954  -2.547  51.803  1   12.317 ? 265  TRP A CA  1 
ATOM   1943 C  C   . TRP A 1 273 ? 25.459  -2.633  51.543  1   13.97  ? 265  TRP A C   1 
ATOM   1944 O  O   . TRP A 1 273 ? 26.107  -1.659  51.193  1   12.674 ? 265  TRP A O   1 
ATOM   1945 C  CB  . TRP A 1 273 ? 23.266  -2.859  50.485  1   13.455 ? 265  TRP A CB  1 
ATOM   1946 C  CG  . TRP A 1 273 ? 21.765  -2.911  50.524  1   13.753 ? 265  TRP A CG  1 
ATOM   1947 C  CD1 . TRP A 1 273 ? 20.933  -2.912  51.613  1   14.347 ? 265  TRP A CD1 1 
ATOM   1948 C  CD2 . TRP A 1 273 ? 20.935  -3.058  49.352  1   13.144 ? 265  TRP A CD2 1 
ATOM   1949 N  NE1 . TRP A 1 273 ? 19.63   -2.952  51.2    1   13.603 ? 265  TRP A NE1 1 
ATOM   1950 C  CE2 . TRP A 1 273 ? 19.614  -3.108  49.836  1   12.748 ? 265  TRP A CE2 1 
ATOM   1951 C  CE3 . TRP A 1 273 ? 21.177  -3.148  47.973  1   12.983 ? 265  TRP A CE3 1 
ATOM   1952 C  CZ2 . TRP A 1 273 ? 18.536  -3.264  48.972  1   12.897 ? 265  TRP A CZ2 1 
ATOM   1953 C  CZ3 . TRP A 1 273 ? 20.104  -3.307  47.117  1   13.957 ? 265  TRP A CZ3 1 
ATOM   1954 C  CH2 . TRP A 1 273 ? 18.778  -3.362  47.609  1   13.78  ? 265  TRP A CH2 1 
ATOM   1955 N  N   . PRO A 1 274 ? 26.049  -3.854  51.685  1   13.906 ? 266  PRO A N   1 
ATOM   1956 C  CA  . PRO A 1 274 ? 27.489  -4.091  51.489  1   14.165 ? 266  PRO A CA  1 
ATOM   1957 C  C   . PRO A 1 274 ? 27.919  -4.181  50.041  1   14.28  ? 266  PRO A C   1 
ATOM   1958 O  O   . PRO A 1 274 ? 28.475  -5.188  49.591  1   15.208 ? 266  PRO A O   1 
ATOM   1959 C  CB  . PRO A 1 274 ? 27.664  -5.394  52.287  1   13.8   ? 266  PRO A CB  1 
ATOM   1960 C  CG  . PRO A 1 274 ? 26.409  -6.157  52.01   1   13.849 ? 266  PRO A CG  1 
ATOM   1961 C  CD  . PRO A 1 274 ? 25.365  -5.04   52.22   1   13.66  ? 266  PRO A CD  1 
ATOM   1962 N  N   . PHE A 1 275 ? 27.555  -3.144  49.26   1   13.337 ? 267  PHE A N   1 
ATOM   1963 C  CA  . PHE A 1 275 ? 28.067  -2.966  47.913  1   13.663 ? 267  PHE A CA  1 
ATOM   1964 C  C   . PHE A 1 275 ? 28.896  -1.699  47.917  1   13.394 ? 267  PHE A C   1 
ATOM   1965 O  O   . PHE A 1 275 ? 28.546  -0.749  48.597  1   14.762 ? 267  PHE A O   1 
ATOM   1966 C  CB  . PHE A 1 275 ? 27.017  -2.852  46.794  1   13.534 ? 267  PHE A CB  1 
ATOM   1967 C  CG  . PHE A 1 275 ? 26.113  -4.065  46.667  1   14.16  ? 267  PHE A CG  1 
ATOM   1968 C  CD1 . PHE A 1 275 ? 25.012  -4.211  47.528  1   14.343 ? 267  PHE A CD1 1 
ATOM   1969 C  CD2 . PHE A 1 275 ? 26.307  -5.04   45.659  1   13.611 ? 267  PHE A CD2 1 
ATOM   1970 C  CE1 . PHE A 1 275 ? 24.148  -5.327  47.452  1   14.866 ? 267  PHE A CE1 1 
ATOM   1971 C  CE2 . PHE A 1 275 ? 25.456  -6.155  45.579  1   13.057 ? 267  PHE A CE2 1 
ATOM   1972 C  CZ  . PHE A 1 275 ? 24.381  -6.298  46.476  1   14.693 ? 267  PHE A CZ  1 
ATOM   1973 N  N   . GLU A 1 276 ? 29.957  -1.668  47.099  1   12.879 ? 268  GLU A N   1 
ATOM   1974 C  CA  . GLU A 1 276 ? 30.721  -0.457  46.911  1   14.318 ? 268  GLU A CA  1 
ATOM   1975 C  C   . GLU A 1 276 ? 30.796  -0.14   45.431  1   13.325 ? 268  GLU A C   1 
ATOM   1976 O  O   . GLU A 1 276 ? 30.846  -1.041  44.597  1   13.643 ? 268  GLU A O   1 
ATOM   1977 C  CB  . GLU A 1 276 ? 32.1    -0.585  47.547  1   15.444 ? 268  GLU A CB  1 
ATOM   1978 C  CG  . GLU A 1 276 ? 32.953  0.687   47.467  1   17.813 ? 268  GLU A CG  1 
ATOM   1979 C  CD  . GLU A 1 276 ? 34.129  0.697   48.466  1   20.581 ? 268  GLU A CD  1 
ATOM   1980 O  OE1 . GLU A 1 276 ? 34.468  -0.371  48.978  1   21.921 ? 268  GLU A OE1 1 
ATOM   1981 O  OE2 . GLU A 1 276 ? 34.646  1.788   48.781  1   23.386 ? 268  GLU A OE2 1 
ATOM   1982 N  N   . ALA A 1 277 ? 30.752  1.166   45.158  1   13.197 ? 269  ALA A N   1 
ATOM   1983 C  CA  . ALA A 1 277 ? 30.895  1.682   43.795  1   14.401 ? 269  ALA A CA  1 
ATOM   1984 C  C   . ALA A 1 277 ? 32.356  2.006   43.512  1   17.024 ? 269  ALA A C   1 
ATOM   1985 O  O   . ALA A 1 277 ? 33.049  2.484   44.416  1   19.689 ? 269  ALA A O   1 
ATOM   1986 C  CB  . ALA A 1 277 ? 30.06   2.928   43.613  1   15.724 ? 269  ALA A CB  1 
ATOM   1987 N  N   . ASN A 1 278 ? 32.787  1.758   42.276  1   16.277 ? 270  ASN A N   1 
ATOM   1988 C  CA  . ASN A 1 278 ? 34.182  2.027   41.916  1   16.515 ? 270  ASN A CA  1 
ATOM   1989 C  C   . ASN A 1 278 ? 34.181  2.66    40.52   1   14.543 ? 270  ASN A C   1 
ATOM   1990 O  O   . ASN A 1 278 ? 33.791  1.983   39.566  1   15.533 ? 270  ASN A O   1 
ATOM   1991 C  CB  . ASN A 1 278 ? 34.946  0.71    41.959  1   16.709 ? 270  ASN A CB  1 
ATOM   1992 C  CG  . ASN A 1 278 ? 36.423  0.973   41.737  1   20.759 ? 270  ASN A CG  1 
ATOM   1993 O  OD1 . ASN A 1 278 ? 36.873  1.098   40.595  1   19.312 ? 270  ASN A OD1 1 
ATOM   1994 N  ND2 . ASN A 1 278 ? 37.22   1.109   42.798  1   24.495 ? 270  ASN A ND2 1 
ATOM   1995 N  N   . LEU A 1 279 ? 34.657  3.911   40.412  1   15.883 ? 271  LEU A N   1 
ATOM   1996 C  CA  . LEU A 1 279 ? 34.669  4.62    39.14   1   14.776 ? 271  LEU A CA  1 
ATOM   1997 C  C   . LEU A 1 279 ? 35.592  3.936   38.129  1   15.889 ? 271  LEU A C   1 
ATOM   1998 O  O   . LEU A 1 279 ? 35.253  3.838   36.945  1   16.304 ? 271  LEU A O   1 
ATOM   1999 C  CB  . LEU A 1 279 ? 35.062  6.083   39.369  1   17.132 ? 271  LEU A CB  1 
ATOM   2000 C  CG  . LEU A 1 279 ? 34.959  7.006   38.15   1   19.916 ? 271  LEU A CG  1 
ATOM   2001 C  CD1 . LEU A 1 279 ? 33.523  7.138   37.666  1   23.079 ? 271  LEU A CD1 1 
ATOM   2002 C  CD2 . LEU A 1 279 ? 35.508  8.356   38.508  1   22.166 ? 271  LEU A CD2 1 
ATOM   2003 N  N   . GLU A 1 280 ? 36.769  3.46    38.561  1   16.471 ? 272  GLU A N   1 
ATOM   2004 C  CA  . GLU A 1 280 ? 37.697  2.803   37.634  1   17.28  ? 272  GLU A CA  1 
ATOM   2005 C  C   . GLU A 1 280 ? 37.051  1.569   37.015  1   17.982 ? 272  GLU A C   1 
ATOM   2006 O  O   . GLU A 1 280 ? 37.187  1.33    35.803  1   17.256 ? 272  GLU A O   1 
ATOM   2007 C  CB  . GLU A 1 280 ? 39.052  2.552   38.328  1   21.829 ? 272  GLU A CB  1 
ATOM   2008 C  CG  . GLU A 1 280 ? 40.073  1.705   37.551  1   32.038 ? 272  GLU A CG  1 
ATOM   2009 C  CD  . GLU A 1 280 ? 41.387  1.309   38.251  1   43.655 ? 272  GLU A CD  1 
ATOM   2010 O  OE1 . GLU A 1 280 ? 41.519  1.419   39.496  1   47.038 ? 272  GLU A OE1 1 
ATOM   2011 O  OE2 . GLU A 1 280 ? 42.304  0.859   37.518  1   50.366 ? 272  GLU A OE2 1 
ATOM   2012 N  N   . ARG A 1 281 ? 36.364  0.751   37.821  1   16.522 ? 273  ARG A N   1 
ATOM   2013 C  CA  . ARG A 1 281 ? 35.672  -0.434  37.31   1   16.456 ? 273  ARG A CA  1 
ATOM   2014 C  C   . ARG A 1 281 ? 34.63   -0.008  36.258  1   16.236 ? 273  ARG A C   1 
ATOM   2015 O  O   . ARG A 1 281 ? 34.496  -0.653  35.222  1   16.3   ? 273  ARG A O   1 
ATOM   2016 C  CB  . ARG A 1 281 ? 35.047  -1.274  38.446  1   16.468 ? 273  ARG A CB  1 
ATOM   2017 C  CG  . ARG A 1 281 ? 34.219  -2.441  37.938  1   16.528 ? 273  ARG A CG  1 
ATOM   2018 C  CD  . ARG A 1 281 ? 33.717  -3.332  39.078  1   14.987 ? 273  ARG A CD  1 
ATOM   2019 N  NE  . ARG A 1 281 ? 32.821  -2.595  39.987  1   16.207 ? 273  ARG A NE  1 
ATOM   2020 C  CZ  . ARG A 1 281 ? 33.029  -2.332  41.278  1   14.806 ? 273  ARG A CZ  1 
ATOM   2021 N  NH1 . ARG A 1 281 ? 34.108  -2.835  41.91   1   15.905 ? 273  ARG A NH1 1 
ATOM   2022 N  NH2 . ARG A 1 281 ? 32.157  -1.569  41.921  1   16.186 ? 273  ARG A NH2 1 
ATOM   2023 N  N   . MET A 1 282 ? 33.869  1.047   36.559  1   14.967 ? 274  MET A N   1 
ATOM   2024 C  CA  . MET A 1 282 ? 32.832  1.493   35.619  1   14.997 ? 274  MET A CA  1 
ATOM   2025 C  C   . MET A 1 282 ? 33.487  1.977   34.327  1   16.948 ? 274  MET A C   1 
ATOM   2026 O  O   . MET A 1 282 ? 33.011  1.63    33.251  1   14.966 ? 274  MET A O   1 
ATOM   2027 C  CB  . MET A 1 282 ? 32.033  2.647   36.22   1   14.788 ? 274  MET A CB  1 
ATOM   2028 C  CG  . MET A 1 282 ? 31.115  2.108   37.305  1   15.657 ? 274  MET A CG  1 
ATOM   2029 S  SD  . MET A 1 282 ? 29.982  3.363   37.898  1   18.819 ? 274  MET A SD  1 
ATOM   2030 C  CE  . MET A 1 282 ? 30.559  3.688   39.56   1   17.926 ? 274  MET A CE  1 
ATOM   2031 N  N   . LYS A 1 283 ? 34.588  2.738   34.432  1   16.402 ? 275  LYS A N   1 
ATOM   2032 C  CA  . LYS A 1 283 ? 35.242  3.189   33.204  1   15.904 ? 275  LYS A CA  1 
ATOM   2033 C  C   . LYS A 1 283 ? 35.731  2.003   32.363  1   16.114 ? 275  LYS A C   1 
ATOM   2034 O  O   . LYS A 1 283 ? 35.718  2.082   31.124  1   16.904 ? 275  LYS A O   1 
ATOM   2035 C  CB  . LYS A 1 283 ? 36.39   4.164   33.476  1   16.485 ? 275  LYS A CB  1 
ATOM   2036 C  CG  . LYS A 1 283 ? 35.936  5.534   34.001  1   19.844 ? 275  LYS A CG  1 
ATOM   2037 C  CD  . LYS A 1 283 ? 37.156  6.433   34.234  1   21.955 ? 275  LYS A CD  1 
ATOM   2038 C  CE  . LYS A 1 283 ? 36.684  7.841   34.483  1   24.369 ? 275  LYS A CE  1 
ATOM   2039 N  NZ  . LYS A 1 283 ? 37.817  8.79    34.401  1   36.201 ? 275  LYS A NZ  1 
ATOM   2040 N  N   . ALA A 1 284 ? 36.12   0.902   33.024  1   14.836 ? 276  ALA A N   1 
ATOM   2041 C  CA  . ALA A 1 284 ? 36.566  -0.31   32.351  1   15.234 ? 276  ALA A CA  1 
ATOM   2042 C  C   . ALA A 1 284 ? 35.42   -1.161  31.828  1   16.166 ? 276  ALA A C   1 
ATOM   2043 O  O   . ALA A 1 284 ? 35.629  -2.207  31.217  1   15.881 ? 276  ALA A O   1 
ATOM   2044 C  CB  . ALA A 1 284 ? 37.425  -1.13   33.34   1   16.304 ? 276  ALA A CB  1 
ATOM   2045 N  N   . GLY A 1 285 ? 34.173  -0.659  32.018  1   15.561 ? 277  GLY A N   1 
ATOM   2046 C  CA  . GLY A 1 285 ? 33.007  -1.337  31.459  1   16.304 ? 277  GLY A CA  1 
ATOM   2047 C  C   . GLY A 1 285 ? 32.356  -2.367  32.391  1   14.27  ? 277  GLY A C   1 
ATOM   2048 O  O   . GLY A 1 285 ? 31.522  -3.136  31.947  1   17.318 ? 277  GLY A O   1 
ATOM   2049 N  N   . GLY A 1 286 ? 32.755  -2.361  33.668  1   15.615 ? 278  GLY A N   1 
ATOM   2050 C  CA  . GLY A 1 286 ? 32.202  -3.284  34.63   1   14.937 ? 278  GLY A CA  1 
ATOM   2051 C  C   . GLY A 1 286 ? 30.989  -2.667  35.345  1   12.878 ? 278  GLY A C   1 
ATOM   2052 O  O   . GLY A 1 286 ? 30.636  -1.523  35.082  1   15.325 ? 278  GLY A O   1 
ATOM   2053 N  N   . HIS A 1 287 ? 30.438  -3.46   36.26   1   14.334 ? 279  HIS A N   1 
ATOM   2054 C  CA  . HIS A 1 287 ? 29.251  -3.033  37.002  1   14.318 ? 279  HIS A CA  1 
ATOM   2055 C  C   . HIS A 1 287 ? 29.56   -1.877  37.941  1   13.921 ? 279  HIS A C   1 
ATOM   2056 O  O   . HIS A 1 287 ? 30.661  -1.704  38.47   1   14.884 ? 279  HIS A O   1 
ATOM   2057 C  CB  . HIS A 1 287 ? 28.663  -4.23   37.759  1   13.876 ? 279  HIS A CB  1 
ATOM   2058 C  CG  . HIS A 1 287 ? 27.813  -5.091  36.895  1   14.834 ? 279  HIS A CG  1 
ATOM   2059 N  ND1 . HIS A 1 287 ? 26.7    -4.639  36.199  1   15.115 ? 279  HIS A ND1 1 
ATOM   2060 C  CD2 . HIS A 1 287 ? 27.897  -6.455  36.685  1   16.249 ? 279  HIS A CD2 1 
ATOM   2061 C  CE1 . HIS A 1 287 ? 26.196  -5.688  35.545  1   17.524 ? 279  HIS A CE1 1 
ATOM   2062 N  NE2 . HIS A 1 287 ? 26.847  -6.8    35.875  1   16.06  ? 279  HIS A NE2 1 
ATOM   2063 N  N   . HIS A 1 288 ? 28.548  -1.042  38.163  1   12.942 ? 280  HIS A N   1 
ATOM   2064 C  CA  . HIS A 1 288 ? 28.616  0.037   39.148  1   12.702 ? 280  HIS A CA  1 
ATOM   2065 C  C   . HIS A 1 288 ? 28.945  -0.509  40.539  1   12.966 ? 280  HIS A C   1 
ATOM   2066 O  O   . HIS A 1 288 ? 29.876  -0.006  41.203  1   13.511 ? 280  HIS A O   1 
ATOM   2067 C  CB  . HIS A 1 288 ? 27.256  0.748   39.114  1   13.823 ? 280  HIS A CB  1 
ATOM   2068 C  CG  . HIS A 1 288 ? 27.175  1.972   40.001  1   12.873 ? 280  HIS A CG  1 
ATOM   2069 N  ND1 . HIS A 1 288 ? 27.027  3.206   39.402  1   12.528 ? 280  HIS A ND1 1 
ATOM   2070 C  CD2 . HIS A 1 288 ? 27.217  2.168   41.327  1   13.995 ? 280  HIS A CD2 1 
ATOM   2071 C  CE1 . HIS A 1 288 ? 26.943  4.135   40.373  1   12.877 ? 280  HIS A CE1 1 
ATOM   2072 N  NE2 . HIS A 1 288 ? 27.046  3.53    41.556  1   13.953 ? 280  HIS A NE2 1 
ATOM   2073 N  N   . TRP A 1 289 ? 28.187  -1.509  40.984  1   11.854 ? 281  TRP A N   1 
ATOM   2074 C  CA  . TRP A 1 289 ? 28.311  -2.08   42.303  1   12.932 ? 281  TRP A CA  1 
ATOM   2075 C  C   . TRP A 1 289 ? 29.005  -3.432  42.283  1   13.485 ? 281  TRP A C   1 
ATOM   2076 O  O   . TRP A 1 289 ? 28.787  -4.218  41.35   1   14.395 ? 281  TRP A O   1 
ATOM   2077 C  CB  . TRP A 1 289 ? 26.882  -2.356  42.85   1   12.671 ? 281  TRP A CB  1 
ATOM   2078 C  CG  . TRP A 1 289 ? 26.024  -1.121  42.991  1   13.269 ? 281  TRP A CG  1 
ATOM   2079 C  CD1 . TRP A 1 289 ? 24.89   -0.799  42.278  1   12.867 ? 281  TRP A CD1 1 
ATOM   2080 C  CD2 . TRP A 1 289 ? 26.302  -0.03   43.879  1   13.052 ? 281  TRP A CD2 1 
ATOM   2081 N  NE1 . TRP A 1 289 ? 24.386  0.389   42.73   1   12.541 ? 281  TRP A NE1 1 
ATOM   2082 C  CE2 . TRP A 1 289 ? 25.249  0.893   43.692  1   12.297 ? 281  TRP A CE2 1 
ATOM   2083 C  CE3 . TRP A 1 289 ? 27.31   0.244   44.845  1   12.375 ? 281  TRP A CE3 1 
ATOM   2084 C  CZ2 . TRP A 1 289 ? 25.198  2.102   44.395  1   12.848 ? 281  TRP A CZ2 1 
ATOM   2085 C  CZ3 . TRP A 1 289 ? 27.261  1.443   45.538  1   12.77  ? 281  TRP A CZ3 1 
ATOM   2086 C  CH2 . TRP A 1 289 ? 26.217  2.388   45.287  1   12.769 ? 281  TRP A CH2 1 
ATOM   2087 N  N   . ALA A 1 290 ? 29.736  -3.711  43.37   1   13.576 ? 282  ALA A N   1 
ATOM   2088 C  CA  . ALA A 1 290 ? 30.232  -5.053  43.653  1   13.883 ? 282  ALA A CA  1 
ATOM   2089 C  C   . ALA A 1 290 ? 29.999  -5.359  45.129  1   13.155 ? 282  ALA A C   1 
ATOM   2090 O  O   . ALA A 1 290 ? 30.314  -4.518  45.991  1   13.896 ? 282  ALA A O   1 
ATOM   2091 C  CB  . ALA A 1 290 ? 31.702  -5.106  43.352  1   14.264 ? 282  ALA A CB  1 
ATOM   2092 N  N   . TYR A 1 291 ? 29.436  -6.542  45.406  1   13.502 ? 283  TYR A N   1 
ATOM   2093 C  CA  . TYR A 1 291 ? 29.197  -7.003  46.775  1   13.201 ? 283  TYR A CA  1 
ATOM   2094 C  C   . TYR A 1 291 ? 30.532  -7.18   47.49   1   14.773 ? 283  TYR A C   1 
ATOM   2095 O  O   . TYR A 1 291 ? 31.498  -7.63   46.842  1   15.735 ? 283  TYR A O   1 
ATOM   2096 C  CB  . TYR A 1 291 ? 28.427  -8.334  46.694  1   13.544 ? 283  TYR A CB  1 
ATOM   2097 C  CG  . TYR A 1 291 ? 27.908  -8.785  48.056  1   13.28  ? 283  TYR A CG  1 
ATOM   2098 C  CD1 . TYR A 1 291 ? 28.724  -9.536  48.949  1   13.637 ? 283  TYR A CD1 1 
ATOM   2099 C  CD2 . TYR A 1 291 ? 26.624  -8.425  48.488  1   13.157 ? 283  TYR A CD2 1 
ATOM   2100 C  CE1 . TYR A 1 291 ? 28.234  -9.93   50.177  1   13.938 ? 283  TYR A CE1 1 
ATOM   2101 C  CE2 . TYR A 1 291 ? 26.15   -8.82   49.728  1   13.564 ? 283  TYR A CE2 1 
ATOM   2102 C  CZ  . TYR A 1 291 ? 26.964  -9.542  50.59   1   14.258 ? 283  TYR A CZ  1 
ATOM   2103 O  OH  . TYR A 1 291 ? 26.465  -9.924  51.81   1   15.669 ? 283  TYR A OH  1 
ATOM   2104 N  N   . ASP A 1 292 ? 30.592  -6.806  48.773  1   14.533 ? 284  ASP A N   1 
ATOM   2105 C  CA  . ASP A 1 292 ? 31.814  -6.981  49.533  1   14.451 ? 284  ASP A CA  1 
ATOM   2106 C  C   . ASP A 1 292 ? 31.462  -7.671  50.848  1   15.179 ? 284  ASP A C   1 
ATOM   2107 O  O   . ASP A 1 292 ? 30.851  -7.057  51.728  1   14.837 ? 284  ASP A O   1 
ATOM   2108 C  CB  . ASP A 1 292 ? 32.511  -5.649  49.707  1   15.055 ? 284  ASP A CB  1 
ATOM   2109 C  CG  . ASP A 1 292 ? 33.854  -5.683  50.43   1   17.555 ? 284  ASP A CG  1 
ATOM   2110 O  OD1 . ASP A 1 292 ? 34.207  -6.748  50.959  1   17.461 ? 284  ASP A OD1 1 
ATOM   2111 O  OD2 . ASP A 1 292 ? 34.528  -4.617  50.452  1   19.021 ? 284  ASP A OD2 1 
ATOM   2112 N  N   . TYR A 1 293 ? 31.923  -8.945  51.014  1   14.924 ? 285  TYR A N   1 
ATOM   2113 C  CA  . TYR A 1 293 ? 31.699  -9.724  52.23   1   16.297 ? 285  TYR A CA  1 
ATOM   2114 C  C   . TYR A 1 293 ? 32.345  -9.082  53.454  1   15.585 ? 285  TYR A C   1 
ATOM   2115 O  O   . TYR A 1 293 ? 31.937  -9.408  54.574  1   17.855 ? 285  TYR A O   1 
ATOM   2116 C  CB  . TYR A 1 293 ? 32.242  -11.159 52.056  1   16.466 ? 285  TYR A CB  1 
ATOM   2117 C  CG  . TYR A 1 293 ? 31.326  -11.993 51.179  1   16.595 ? 285  TYR A CG  1 
ATOM   2118 C  CD1 . TYR A 1 293 ? 30.122  -12.518 51.701  1   16.566 ? 285  TYR A CD1 1 
ATOM   2119 C  CD2 . TYR A 1 293 ? 31.637  -12.243 49.835  1   16.037 ? 285  TYR A CD2 1 
ATOM   2120 C  CE1 . TYR A 1 293 ? 29.238  -13.226 50.879  1   18.77  ? 285  TYR A CE1 1 
ATOM   2121 C  CE2 . TYR A 1 293 ? 30.811  -13.036 49.058  1   16.743 ? 285  TYR A CE2 1 
ATOM   2122 C  CZ  . TYR A 1 293 ? 29.603  -13.507 49.572  1   18.978 ? 285  TYR A CZ  1 
ATOM   2123 O  OH  . TYR A 1 293 ? 28.8    -14.146 48.659  1   22.483 ? 285  TYR A OH  1 
ATOM   2124 N  N   . THR A 1 294 ? 33.324  -8.209  53.257  1   16.417 ? 286  THR A N   1 
ATOM   2125 C  CA  . THR A 1 294 ? 34.023  -7.589  54.387  1   17.134 ? 286  THR A CA  1 
ATOM   2126 C  C   . THR A 1 294 ? 33.318  -6.318  54.867  1   18.483 ? 286  THR A C   1 
ATOM   2127 O  O   . THR A 1 294 ? 33.718  -5.784  55.913  1   19.874 ? 286  THR A O   1 
ATOM   2128 C  CB  . THR A 1 294 ? 35.497  -7.286  54.087  1   18.22  ? 286  THR A CB  1 
ATOM   2129 O  OG1 . THR A 1 294 ? 35.601  -6.169  53.233  1   18.977 ? 286  THR A OG1 1 
ATOM   2130 C  CG2 . THR A 1 294 ? 36.289  -8.463  53.514  1   20.245 ? 286  THR A CG2 1 
ATOM   2131 N  N   . LYS A 1 295 ? 32.289  -5.824  54.143  1   15.453 ? 287  LYS A N   1 
ATOM   2132 C  CA  . LYS A 1 295 ? 31.59   -4.633  54.612  1   15.892 ? 287  LYS A CA  1 
ATOM   2133 C  C   . LYS A 1 295 ? 30.502  -5.067  55.588  1   15.793 ? 287  LYS A C   1 
ATOM   2134 O  O   . LYS A 1 295 ? 29.671  -5.923  55.262  1   15.627 ? 287  LYS A O   1 
ATOM   2135 C  CB  . LYS A 1 295 ? 30.938  -3.853  53.45   1   15.628 ? 287  LYS A CB  1 
ATOM   2136 C  CG  . LYS A 1 295 ? 31.894  -3.064  52.552  1   18.409 ? 287  LYS A CG  1 
ATOM   2137 C  CD  . LYS A 1 295 ? 32.624  -1.945  53.258  1   18.332 ? 287  LYS A CD  1 
ATOM   2138 C  CE  . LYS A 1 295 ? 33.317  -1.191  52.184  1   20.373 ? 287  LYS A CE  1 
ATOM   2139 N  NZ  . LYS A 1 295 ? 34.364  -0.32   52.74   1   26.518 ? 287  LYS A NZ  1 
ATOM   2140 N  N   . PRO A 1 296 ? 30.378  -4.429  56.77   1   15.258 ? 288  PRO A N   1 
ATOM   2141 C  CA  . PRO A 1 296 ? 29.276  -4.747  57.682  1   14.182 ? 288  PRO A CA  1 
ATOM   2142 C  C   . PRO A 1 296 ? 28.06   -3.925  57.245  1   14.161 ? 288  PRO A C   1 
ATOM   2143 O  O   . PRO A 1 296 ? 28.2    -2.803  56.689  1   15.159 ? 288  PRO A O   1 
ATOM   2144 C  CB  . PRO A 1 296 ? 29.808  -4.257  59.051  1   16.912 ? 288  PRO A CB  1 
ATOM   2145 C  CG  . PRO A 1 296 ? 30.653  -3.047  58.681  1   17.637 ? 288  PRO A CG  1 
ATOM   2146 C  CD  . PRO A 1 296 ? 31.309  -3.434  57.356  1   15.306 ? 288  PRO A CD  1 
ATOM   2147 N  N   . ILE A 1 297 ? 26.871  -4.502  57.523  1   14.021 ? 289  ILE A N   1 
ATOM   2148 C  CA  . ILE A 1 297 ? 25.66   -3.684  57.428  1   14.28  ? 289  ILE A CA  1 
ATOM   2149 C  C   . ILE A 1 297 ? 25.861  -2.436  58.291  1   14.473 ? 289  ILE A C   1 
ATOM   2150 O  O   . ILE A 1 297 ? 26.344  -2.549  59.432  1   15.583 ? 289  ILE A O   1 
ATOM   2151 C  CB  . ILE A 1 297 ? 24.456  -4.488  57.943  1   14.283 ? 289  ILE A CB  1 
ATOM   2152 C  CG1 . ILE A 1 297 ? 24.105  -5.61   56.911  1   14.487 ? 289  ILE A CG1 1 
ATOM   2153 C  CG2 . ILE A 1 297 ? 23.247  -3.566  58.193  1   15.34  ? 289  ILE A CG2 1 
ATOM   2154 C  CD1 . ILE A 1 297 ? 23.177  -6.666  57.5    1   13.854 ? 289  ILE A CD1 1 
ATOM   2155 N  N   . THR A 1 298 ? 25.616  -1.261  57.712  1   14.024 ? 290  THR A N   1 
ATOM   2156 C  CA  . THR A 1 298 ? 25.905  -0.001  58.378  1   13.344 ? 290  THR A CA  1 
ATOM   2157 C  C   . THR A 1 298 ? 24.65   0.861   58.304  1   13.239 ? 290  THR A C   1 
ATOM   2158 O  O   . THR A 1 298 ? 23.895  0.79    57.325  1   14.024 ? 290  THR A O   1 
ATOM   2159 C  CB  . THR A 1 298 ? 27.101  0.649   57.656  1   13.707 ? 290  THR A CB  1 
ATOM   2160 O  OG1 . THR A 1 298 ? 28.242  -0.21   57.87   1   14.737 ? 290  THR A OG1 1 
ATOM   2161 C  CG2 . THR A 1 298 ? 27.469  2.024   58.214  1   15.35  ? 290  THR A CG2 1 
ATOM   2162 N  N   . TRP A 1 299 ? 24.415  1.644   59.346  1   14.436 ? 291  TRP A N   1 
ATOM   2163 C  CA  . TRP A 1 299 ? 23.263  2.52    59.483  1   13.117 ? 291  TRP A CA  1 
ATOM   2164 C  C   . TRP A 1 299 ? 23.758  3.922   59.702  1   14.243 ? 291  TRP A C   1 
ATOM   2165 O  O   . TRP A 1 299 ? 24.713  4.116   60.48   1   15.608 ? 291  TRP A O   1 
ATOM   2166 C  CB  . TRP A 1 299 ? 22.346  2.106   60.638  1   13.295 ? 291  TRP A CB  1 
ATOM   2167 C  CG  . TRP A 1 299 ? 21.874  0.678   60.589  1   15.869 ? 291  TRP A CG  1 
ATOM   2168 C  CD1 . TRP A 1 299 ? 22.521  -0.425  61.1    1   15.672 ? 291  TRP A CD1 1 
ATOM   2169 C  CD2 . TRP A 1 299 ? 20.616  0.208   60.045  1   15.536 ? 291  TRP A CD2 1 
ATOM   2170 N  NE1 . TRP A 1 299 ? 21.719  -1.536  60.926  1   16.715 ? 291  TRP A NE1 1 
ATOM   2171 C  CE2 . TRP A 1 299 ? 20.561  -1.192  60.289  1   15.743 ? 291  TRP A CE2 1 
ATOM   2172 C  CE3 . TRP A 1 299 ? 19.523  0.826   59.413  1   15.325 ? 291  TRP A CE3 1 
ATOM   2173 C  CZ2 . TRP A 1 299 ? 19.469  -1.958  59.887  1   16.699 ? 291  TRP A CZ2 1 
ATOM   2174 C  CZ3 . TRP A 1 299 ? 18.421  0.063   59.052  1   17.636 ? 291  TRP A CZ3 1 
ATOM   2175 C  CH2 . TRP A 1 299 ? 18.417  -1.324  59.272  1   17.005 ? 291  TRP A CH2 1 
ATOM   2176 N  N   . ILE A 1 300 ? 23.159  4.893   59.013  1   12.971 ? 292  ILE A N   1 
ATOM   2177 C  CA  . ILE A 1 300 ? 23.467  6.298   59.292  1   12.576 ? 292  ILE A CA  1 
ATOM   2178 C  C   . ILE A 1 300 ? 22.263  6.932   59.954  1   12.695 ? 292  ILE A C   1 
ATOM   2179 O  O   . ILE A 1 300 ? 21.202  7.058   59.325  1   13.502 ? 292  ILE A O   1 
ATOM   2180 C  CB  . ILE A 1 300 ? 23.842  7.022   57.985  1   13.336 ? 292  ILE A CB  1 
ATOM   2181 C  CG1 . ILE A 1 300 ? 25.003  6.348   57.235  1   13.985 ? 292  ILE A CG1 1 
ATOM   2182 C  CG2 . ILE A 1 300 ? 24.081  8.533   58.227  1   14.465 ? 292  ILE A CG2 1 
ATOM   2183 C  CD1 . ILE A 1 300 ? 25.342  7.022   55.915  1   14.434 ? 292  ILE A CD1 1 
ATOM   2184 N  N   . THR A 1 301 ? 22.444  7.388   61.2    1   13.704 ? 293  THR A N   1 
ATOM   2185 C  CA  . THR A 1 301 ? 21.372  8.094   61.891  1   14.565 ? 293  THR A CA  1 
ATOM   2186 C  C   . THR A 1 301 ? 21.485  9.602   61.588  1   15.646 ? 293  THR A C   1 
ATOM   2187 O  O   . THR A 1 301 ? 22.539  10.214  61.798  1   15.46  ? 293  THR A O   1 
ATOM   2188 C  CB  . THR A 1 301 ? 21.359  7.788   63.398  1   14.812 ? 293  THR A CB  1 
ATOM   2189 O  OG1 . THR A 1 301 ? 22.668  8.039   63.948  1   15.333 ? 293  THR A OG1 1 
ATOM   2190 C  CG2 . THR A 1 301 ? 20.992  6.353   63.7    1   15.88  ? 293  THR A CG2 1 
ATOM   2191 N  N   . ILE A 1 302 ? 20.377  10.204  61.134  1   13.532 ? 294  ILE A N   1 
ATOM   2192 C  CA  . ILE A 1 302 ? 20.348  11.61   60.788  1   15.495 ? 294  ILE A CA  1 
ATOM   2193 C  C   . ILE A 1 302 ? 19.279  12.21   61.694  1   15.084 ? 294  ILE A C   1 
ATOM   2194 O  O   . ILE A 1 302 ? 18.079  11.943  61.514  1   14.271 ? 294  ILE A O   1 
ATOM   2195 C  CB  . ILE A 1 302 ? 20.015  11.881  59.309  1   14.401 ? 294  ILE A CB  1 
ATOM   2196 C  CG1 . ILE A 1 302 ? 21.01   11.195  58.393  1   14.76  ? 294  ILE A CG1 1 
ATOM   2197 C  CG2 . ILE A 1 302 ? 20.005  13.408  59.06   1   15.797 ? 294  ILE A CG2 1 
ATOM   2198 C  CD1 . ILE A 1 302 ? 20.635  11.266  56.905  1   15.731 ? 294  ILE A CD1 1 
ATOM   2199 N  N   . PRO A 1 303 ? 19.638  12.967  62.764  1   14.169 ? 295  PRO A N   1 
ATOM   2200 C  CA  . PRO A 1 303 ? 18.563  13.576  63.545  1   15.025 ? 295  PRO A CA  1 
ATOM   2201 C  C   . PRO A 1 303 ? 17.753  14.492  62.641  1   14.051 ? 295  PRO A C   1 
ATOM   2202 O  O   . PRO A 1 303 ? 18.279  15.226  61.816  1   16.261 ? 295  PRO A O   1 
ATOM   2203 C  CB  . PRO A 1 303 ? 19.36   14.395  64.609  1   16.79  ? 295  PRO A CB  1 
ATOM   2204 C  CG  . PRO A 1 303 ? 20.632  13.605  64.726  1   15.889 ? 295  PRO A CG  1 
ATOM   2205 C  CD  . PRO A 1 303 ? 20.992  13.199  63.312  1   15.446 ? 295  PRO A CD  1 
ATOM   2206 N  N   . ARG A 1 304 ? 16.425  14.391  62.736  1   13.92  ? 296  ARG A N   1 
ATOM   2207 C  CA  . ARG A 1 304 ? 15.586  15.171  61.823  1   14.693 ? 296  ARG A CA  1 
ATOM   2208 C  C   . ARG A 1 304 ? 15.78   16.654  62.125  1   16.835 ? 296  ARG A C   1 
ATOM   2209 O  O   . ARG A 1 304 ? 15.831  17.025  63.312  1   18.841 ? 296  ARG A O   1 
ATOM   2210 C  CB  . ARG A 1 304 ? 14.118  14.736  61.895  1   15.568 ? 296  ARG A CB  1 
ATOM   2211 C  CG  . ARG A 1 304 ? 13.982  13.3    61.355  1   15.315 ? 296  ARG A CG  1 
ATOM   2212 C  CD  . ARG A 1 304 ? 12.57   12.771  61.548  1   13.844 ? 296  ARG A CD  1 
ATOM   2213 N  NE  . ARG A 1 304 ? 11.618  13.461  60.678  1   13.243 ? 296  ARG A NE  1 
ATOM   2214 C  CZ  . ARG A 1 304 ? 10.282  13.327  60.765  1   13.62  ? 296  ARG A CZ  1 
ATOM   2215 N  NH1 . ARG A 1 304 ? 9.754   12.385  61.55   1   14.852 ? 296  ARG A NH1 1 
ATOM   2216 N  NH2 . ARG A 1 304 ? 9.506   14.062  59.992  1   13.391 ? 296  ARG A NH2 1 
ATOM   2217 N  N   . GLY A 1 305 ? 15.871  17.44   61.058  1   16.334 ? 297  GLY A N   1 
ATOM   2218 C  CA  . GLY A 1 305 ? 16.156  18.872  61.179  1   17.436 ? 297  GLY A CA  1 
ATOM   2219 C  C   . GLY A 1 305 ? 17.593  19.148  61.629  1   19.638 ? 297  GLY A C   1 
ATOM   2220 O  O   . GLY A 1 305 ? 17.874  20.261  62.059  1   21.348 ? 297  GLY A O   1 
ATOM   2221 N  N   . ALA A 1 306 ? 18.524  18.181  61.544  1   18.039 ? 298  ALA A N   1 
ATOM   2222 C  CA  . ALA A 1 306 ? 19.91   18.418  61.974  1   19.415 ? 298  ALA A CA  1 
ATOM   2223 C  C   . ALA A 1 306 ? 20.461  19.674  61.282  1   19.043 ? 298  ALA A C   1 
ATOM   2224 O  O   . ALA A 1 306 ? 20.208  19.921  60.112  1   20.398 ? 298  ALA A O   1 
ATOM   2225 C  CB  . ALA A 1 306 ? 20.758  17.207  61.612  1   21.029 ? 298  ALA A CB  1 
ATOM   2226 N  N   . LYS A 1 307 ? 21.336  20.39   62.012  1   21.587 ? 299  LYS A N   1 
ATOM   2227 C  CA  . LYS A 1 307 ? 21.924  21.58   61.418  1   22.14  ? 299  LYS A CA  1 
ATOM   2228 C  C   . LYS A 1 307 ? 23.378  21.388  61.01   1   22.912 ? 299  LYS A C   1 
ATOM   2229 O  O   . LYS A 1 307 ? 23.9    22.236  60.291  1   26.468 ? 299  LYS A O   1 
ATOM   2230 C  CB  . LYS A 1 307 ? 21.792  22.705  62.451  1   24.515 ? 299  LYS A CB  1 
ATOM   2231 C  CG  . LYS A 1 307 ? 20.334  23.101  62.661  1   25.839 ? 299  LYS A CG  1 
ATOM   2232 C  CD  . LYS A 1 307 ? 19.644  23.654  61.413  1   26.8   ? 299  LYS A CD  1 
ATOM   2233 C  CE  . LYS A 1 307 ? 18.255  24.003  61.82   1   33.411 ? 299  LYS A CE  1 
ATOM   2234 N  NZ  . LYS A 1 307 ? 17.568  24.786  60.784  1   37.939 ? 299  LYS A NZ  1 
ATOM   2235 N  N   . SER A 1 308 ? 23.991  20.284  61.445  1   19.432 ? 300  SER A N   1 
ATOM   2236 C  CA  . SER A 1 308 ? 25.379  20.029  61.115  1   21.496 ? 300  SER A CA  1 
ATOM   2237 C  C   . SER A 1 308 ? 25.5    18.538  60.82   1   20.187 ? 300  SER A C   1 
ATOM   2238 O  O   . SER A 1 308 ? 24.915  17.735  61.562  1   21.498 ? 300  SER A O   1 
ATOM   2239 C  CB  . SER A 1 308 ? 26.26   20.394  62.317  1   22.072 ? 300  SER A CB  1 
ATOM   2240 O  OG  . SER A 1 308 ? 27.597  19.995  62.05   1   27.852 ? 300  SER A OG  1 
ATOM   2241 N  N   . LYS A 1 309 ? 26.369  18.217  59.861  1   20.39  ? 301  LYS A N   1 
ATOM   2242 C  CA  . LYS A 1 309 ? 26.747  16.826  59.622  1   20.72  ? 301  LYS A CA  1 
ATOM   2243 C  C   . LYS A 1 309 ? 27.438  16.214  60.851  1   20.731 ? 301  LYS A C   1 
ATOM   2244 O  O   . LYS A 1 309 ? 27.491  14.999  61.007  1   20.859 ? 301  LYS A O   1 
ATOM   2245 C  CB  . LYS A 1 309 ? 27.541  16.695  58.318  1   22.016 ? 301  LYS A CB  1 
ATOM   2246 C  CG  . LYS A 1 309 ? 28.92   17.334  58.438  1   24.077 ? 301  LYS A CG  1 
ATOM   2247 C  CD  . LYS A 1 309 ? 29.66   17.273  57.107  1   29.183 ? 301  LYS A CD  1 
ATOM   2248 C  CE  . LYS A 1 309 ? 31.127  17.468  57.407  1   33.087 ? 301  LYS A CE  1 
ATOM   2249 N  NZ  . LYS A 1 309 ? 31.812  17.589  56.126  1   43.498 ? 301  LYS A NZ  1 
ATOM   2250 N  N   . ASP A 1 310 ? 27.897  17.038  61.812  1   22.855 ? 302  ASP A N   1 
ATOM   2251 C  CA  . ASP A 1 310 ? 28.495  16.511  63.04   1   22.225 ? 302  ASP A CA  1 
ATOM   2252 C  C   . ASP A 1 310 ? 27.483  15.742  63.903  1   19.869 ? 302  ASP A C   1 
ATOM   2253 O  O   . ASP A 1 310 ? 27.883  14.975  64.782  1   23.011 ? 302  ASP A O   1 
ATOM   2254 C  CB  . ASP A 1 310 ? 29.103  17.635  63.881  1   27.525 ? 302  ASP A CB  1 
ATOM   2255 C  CG  . ASP A 1 310 ? 30.228  18.423  63.227  1   40.203 ? 302  ASP A CG  1 
ATOM   2256 O  OD1 . ASP A 1 310 ? 30.803  17.956  62.207  1   38.241 ? 302  ASP A OD1 1 
ATOM   2257 O  OD2 . ASP A 1 310 ? 30.504  19.524  63.731  1   47.081 ? 302  ASP A OD2 1 
ATOM   2258 N  N   . GLU A 1 311 ? 26.169  15.959  63.657  1   19.127 ? 303  GLU A N   1 
ATOM   2259 C  CA  . GLU A 1 311 ? 25.128  15.277  64.42   1   18.662 ? 303  GLU A CA  1 
ATOM   2260 C  C   . GLU A 1 311 ? 24.847  13.868  63.882  1   17.123 ? 303  GLU A C   1 
ATOM   2261 O  O   . GLU A 1 311 ? 24.206  13.094  64.594  1   17.796 ? 303  GLU A O   1 
ATOM   2262 C  CB  . GLU A 1 311 ? 23.826  16.048  64.281  1   21.001 ? 303  GLU A CB  1 
ATOM   2263 C  CG  . GLU A 1 311 ? 23.868  17.408  64.995  1   23.929 ? 303  GLU A CG  1 
ATOM   2264 C  CD  . GLU A 1 311 ? 22.537  18.152  64.833  1   25.928 ? 303  GLU A CD  1 
ATOM   2265 O  OE1 . GLU A 1 311 ? 21.467  17.577  65.186  1   25.917 ? 303  GLU A OE1 1 
ATOM   2266 O  OE2 . GLU A 1 311 ? 22.569  19.31   64.315  1   26.934 ? 303  GLU A OE2 1 
ATOM   2267 N  N   . VAL A 1 312 ? 25.352  13.565  62.692  1   17.187 ? 304  VAL A N   1 
ATOM   2268 C  CA  . VAL A 1 312 ? 25.092  12.292  62.033  1   17.427 ? 304  VAL A CA  1 
ATOM   2269 C  C   . VAL A 1 312 ? 26.058  11.259  62.613  1   17.505 ? 304  VAL A C   1 
ATOM   2270 O  O   . VAL A 1 312 ? 27.221  11.579  62.915  1   18.642 ? 304  VAL A O   1 
ATOM   2271 C  CB  . VAL A 1 312 ? 25.326  12.526  60.544  1   18.656 ? 304  VAL A CB  1 
ATOM   2272 C  CG1 . VAL A 1 312 ? 25.356  11.212  59.77   1   19.415 ? 304  VAL A CG1 1 
ATOM   2273 C  CG2 . VAL A 1 312 ? 24.275  13.448  59.923  1   17.905 ? 304  VAL A CG2 1 
ATOM   2274 N  N   . LYS A 1 313 ? 25.573  10.016  62.799  1   16.546 ? 305  LYS A N   1 
ATOM   2275 C  CA  . LYS A 1 313 ? 26.426  8.965   63.318  1   15.936 ? 305  LYS A CA  1 
ATOM   2276 C  C   . LYS A 1 313 ? 26.316  7.714   62.461  1   16.318 ? 305  LYS A C   1 
ATOM   2277 O  O   . LYS A 1 313 ? 25.241  7.46    61.875  1   14.934 ? 305  LYS A O   1 
ATOM   2278 C  CB  . LYS A 1 313 ? 26.084  8.584   64.764  1   18.05  ? 305  LYS A CB  1 
ATOM   2279 C  CG  . LYS A 1 313 ? 26.41   9.728   65.74   1   22.556 ? 305  LYS A CG  1 
ATOM   2280 C  CD  . LYS A 1 313 ? 26.437  9.259   67.195  1   35.098 ? 305  LYS A CD  1 
ATOM   2281 C  CE  . LYS A 1 313 ? 26.819  10.264  68.273  1   39.564 ? 305  LYS A CE  1 
ATOM   2282 N  NZ  . LYS A 1 313 ? 27.921  11.13   67.844  1   52.362 ? 305  LYS A NZ  1 
ATOM   2283 N  N   . TYR A 1 314 ? 27.42   6.956   62.357  1   15.76  ? 306  TYR A N   1 
ATOM   2284 C  CA  . TYR A 1 314 ? 27.461  5.685   61.642  1   13.91  ? 306  TYR A CA  1 
ATOM   2285 C  C   . TYR A 1 314 ? 27.487  4.553   62.66   1   15.822 ? 306  TYR A C   1 
ATOM   2286 O  O   . TYR A 1 314 ? 28.262  4.583   63.637  1   16.393 ? 306  TYR A O   1 
ATOM   2287 C  CB  . TYR A 1 314 ? 28.738  5.586   60.801  1   14.44  ? 306  TYR A CB  1 
ATOM   2288 C  CG  . TYR A 1 314 ? 29.06   6.707   59.827  1   14.894 ? 306  TYR A CG  1 
ATOM   2289 C  CD1 . TYR A 1 314 ? 28.048  7.49    59.245  1   14.636 ? 306  TYR A CD1 1 
ATOM   2290 C  CD2 . TYR A 1 314 ? 30.378  6.948   59.444  1   14.455 ? 306  TYR A CD2 1 
ATOM   2291 C  CE1 . TYR A 1 314 ? 28.333  8.493   58.335  1   14.332 ? 306  TYR A CE1 1 
ATOM   2292 C  CE2 . TYR A 1 314 ? 30.697  7.946   58.536  1   15.744 ? 306  TYR A CE2 1 
ATOM   2293 C  CZ  . TYR A 1 314 ? 29.669  8.707   57.984  1   15.113 ? 306  TYR A CZ  1 
ATOM   2294 O  OH  . TYR A 1 314 ? 29.977  9.685   57.078  1   18.788 ? 306  TYR A OH  1 
ATOM   2295 N  N   . TRP A 1 315 ? 26.667  3.523   62.417  1   14.556 ? 307  TRP A N   1 
ATOM   2296 C  CA  . TRP A 1 315 ? 26.539  2.359   63.29   1   15.037 ? 307  TRP A CA  1 
ATOM   2297 C  C   . TRP A 1 315 ? 26.757  1.11    62.446  1   16.258 ? 307  TRP A C   1 
ATOM   2298 O  O   . TRP A 1 315 ? 26.401  1.109   61.265  1   17.875 ? 307  TRP A O   1 
ATOM   2299 C  CB  . TRP A 1 315 ? 25.144  2.286   63.936  1   15.149 ? 307  TRP A CB  1 
ATOM   2300 C  CG  . TRP A 1 315 ? 24.715  3.56    64.605  1   14.64  ? 307  TRP A CG  1 
ATOM   2301 C  CD1 . TRP A 1 315 ? 24.262  4.686   63.983  1   14.302 ? 307  TRP A CD1 1 
ATOM   2302 C  CD2 . TRP A 1 315 ? 24.728  3.842   66.01   1   17.159 ? 307  TRP A CD2 1 
ATOM   2303 N  NE1 . TRP A 1 315 ? 23.987  5.679   64.905  1   14.978 ? 307  TRP A NE1 1 
ATOM   2304 C  CE2 . TRP A 1 315 ? 24.273  5.177   66.162  1   16.253 ? 307  TRP A CE2 1 
ATOM   2305 C  CE3 . TRP A 1 315 ? 25.062  3.058   67.138  1   17.9   ? 307  TRP A CE3 1 
ATOM   2306 C  CZ2 . TRP A 1 315 ? 24.16   5.764   67.433  1   17.858 ? 307  TRP A CZ2 1 
ATOM   2307 C  CZ3 . TRP A 1 315 ? 24.927  3.637   68.393  1   19.208 ? 307  TRP A CZ3 1 
ATOM   2308 C  CH2 . TRP A 1 315 ? 24.478  4.954   68.517  1   19.033 ? 307  TRP A CH2 1 
ATOM   2309 N  N   . HIS A 1 316 ? 27.271  0.03    63.015  1   14.427 ? 308  HIS A N   1 
ATOM   2310 C  CA  . HIS A 1 316 ? 27.608  -1.123  62.194  1   14.922 ? 308  HIS A CA  1 
ATOM   2311 C  C   . HIS A 1 316 ? 27.294  -2.419  62.919  1   15.066 ? 308  HIS A C   1 
ATOM   2312 O  O   . HIS A 1 316 ? 27.346  -2.474  64.143  1   15.553 ? 308  HIS A O   1 
ATOM   2313 C  CB  . HIS A 1 316 ? 29.057  -1.125  61.691  1   16.72  ? 308  HIS A CB  1 
ATOM   2314 C  CG  . HIS A 1 316 ? 30.014  -1.346  62.821  1   18.707 ? 308  HIS A CG  1 
ATOM   2315 N  ND1 . HIS A 1 316 ? 30.608  -2.54   63.175  1   22.242 ? 308  HIS A ND1 1 
ATOM   2316 C  CD2 . HIS A 1 316 ? 30.452  -0.432  63.691  1   16.744 ? 308  HIS A CD2 1 
ATOM   2317 C  CE1 . HIS A 1 316 ? 31.393  -2.342  64.234  1   16.999 ? 308  HIS A CE1 1 
ATOM   2318 N  NE2 . HIS A 1 316 ? 31.294  -1.088  64.591  1   21.236 ? 308  HIS A NE2 1 
ATOM   2319 N  N   . TRP A 1 317 ? 26.937  -3.443  62.124  1   15.012 ? 309  TRP A N   1 
ATOM   2320 C  CA  . TRP A 1 317 ? 26.788  -4.806  62.611  1   15.932 ? 309  TRP A CA  1 
ATOM   2321 C  C   . TRP A 1 317 ? 27.808  -5.714  61.92   1   15.859 ? 309  TRP A C   1 
ATOM   2322 O  O   . TRP A 1 317 ? 28.992  -5.611  62.21   1   17.195 ? 309  TRP A O   1 
ATOM   2323 C  CB  . TRP A 1 317 ? 25.323  -5.259  62.456  1   16.886 ? 309  TRP A CB  1 
ATOM   2324 C  CG  . TRP A 1 317 ? 25.086  -6.628  63.024  1   15.165 ? 309  TRP A CG  1 
ATOM   2325 C  CD1 . TRP A 1 317 ? 25.331  -7.06   64.309  1   16.66  ? 309  TRP A CD1 1 
ATOM   2326 C  CD2 . TRP A 1 317 ? 24.674  -7.783  62.27   1   16.179 ? 309  TRP A CD2 1 
ATOM   2327 N  NE1 . TRP A 1 317 ? 25.067  -8.407  64.385  1   16.16  ? 309  TRP A NE1 1 
ATOM   2328 C  CE2 . TRP A 1 317 ? 24.649  -8.884  63.161  1   16.047 ? 309  TRP A CE2 1 
ATOM   2329 C  CE3 . TRP A 1 317 ? 24.313  -7.994  60.931  1   15.966 ? 309  TRP A CE3 1 
ATOM   2330 C  CZ2 . TRP A 1 317 ? 24.309  -10.174 62.742  1   16.771 ? 309  TRP A CZ2 1 
ATOM   2331 C  CZ3 . TRP A 1 317 ? 23.941  -9.26   60.537  1   17.45  ? 309  TRP A CZ3 1 
ATOM   2332 C  CH2 . TRP A 1 317 ? 23.944  -10.362 61.413  1   16.753 ? 309  TRP A CH2 1 
ATOM   2333 N  N   . LYS A 1 318 ? 27.358  -6.587  61.003  1   15.117 ? 310  LYS A N   1 
ATOM   2334 C  CA  . LYS A 1 318 ? 28.151  -7.631  60.35   1   14.069 ? 310  LYS A CA  1 
ATOM   2335 C  C   . LYS A 1 318 ? 27.67   -7.692  58.906  1   15.353 ? 310  LYS A C   1 
ATOM   2336 O  O   . LYS A 1 318 ? 26.652  -7.084  58.535  1   15.876 ? 310  LYS A O   1 
ATOM   2337 C  CB  . LYS A 1 318 ? 27.949  -8.992  61.053  1   16.925 ? 310  LYS A CB  1 
ATOM   2338 C  CG  . LYS A 1 318 ? 28.408  -9.039  62.537  1   19.808 ? 310  LYS A CG  1 
ATOM   2339 C  CD  . LYS A 1 318 ? 28.065  -10.41  63.163  1   22.133 ? 310  LYS A CD  1 
ATOM   2340 C  CE  . LYS A 1 318 ? 28.502  -10.536 64.602  1   31.823 ? 310  LYS A CE  1 
ATOM   2341 N  NZ  . LYS A 1 318 ? 27.8    -11.572 65.394  1   33.821 ? 310  LYS A NZ  1 
ATOM   2342 N  N   . ASN A 1 319 ? 28.362  -8.484  58.083  1   14.853 ? 311  ASN A N   1 
ATOM   2343 C  CA  . ASN A 1 319 ? 27.942  -8.555  56.684  1   14.114 ? 311  ASN A CA  1 
ATOM   2344 C  C   . ASN A 1 319 ? 26.598  -9.271  56.526  1   13.688 ? 311  ASN A C   1 
ATOM   2345 O  O   . ASN A 1 319 ? 26.245  -10.173 57.266  1   15.538 ? 311  ASN A O   1 
ATOM   2346 C  CB  . ASN A 1 319 ? 29.013  -9.285  55.864  1   14.599 ? 311  ASN A CB  1 
ATOM   2347 C  CG  . ASN A 1 319 ? 28.687  -9.291  54.384  1   15.401 ? 311  ASN A CG  1 
ATOM   2348 O  OD1 . ASN A 1 319 ? 28.345  -10.348 53.825  1   15.778 ? 311  ASN A OD1 1 
ATOM   2349 N  ND2 . ASN A 1 319 ? 28.82   -8.147  53.735  1   14.488 ? 311  ASN A ND2 1 
ATOM   2350 N  N   . GLY A 1 320 ? 25.826  -8.804  55.522  1   13.129 ? 312  GLY A N   1 
ATOM   2351 C  CA  . GLY A 1 320 ? 24.533  -9.363  55.129  1   13.563 ? 312  GLY A CA  1 
ATOM   2352 C  C   . GLY A 1 320 ? 23.812  -8.279  54.341  1   14.123 ? 312  GLY A C   1 
ATOM   2353 O  O   . GLY A 1 320 ? 24.347  -7.201  54.115  1   13.608 ? 312  GLY A O   1 
ATOM   2354 N  N   . MET A 1 321 ? 22.58   -8.619  53.904  1   13.66  ? 313  MET A N   1 
ATOM   2355 C  CA  . MET A 1 321 ? 21.863  -7.736  52.994  1   12.845 ? 313  MET A CA  1 
ATOM   2356 C  C   . MET A 1 321 ? 20.439  -7.584  53.494  1   12.85  ? 313  MET A C   1 
ATOM   2357 O  O   . MET A 1 321 ? 19.558  -8.407  53.215  1   13.224 ? 313  MET A O   1 
ATOM   2358 C  CB  . MET A 1 321 ? 21.907  -8.275  51.563  1   12.632 ? 313  MET A CB  1 
ATOM   2359 C  CG  . MET A 1 321 ? 21.24   -7.341  50.545  1   13.416 ? 313  MET A CG  1 
ATOM   2360 S  SD  . MET A 1 321 ? 21.81   -7.798  48.891  1   14.423 ? 313  MET A SD  1 
ATOM   2361 C  CE  . MET A 1 321 ? 20.587  -6.902  47.907  1   14.427 ? 313  MET A CE  1 
ATOM   2362 N  N   . PRO A 1 322 ? 20.14   -6.479  54.24   1   12.405 ? 314  PRO A N   1 
ATOM   2363 C  CA  . PRO A 1 322 ? 18.791  -6.227  54.727  1   11.827 ? 314  PRO A CA  1 
ATOM   2364 C  C   . PRO A 1 322 ? 18.186  -5.352  53.614  1   11.373 ? 314  PRO A C   1 
ATOM   2365 O  O   . PRO A 1 322 ? 18.615  -4.216  53.367  1   13.035 ? 314  PRO A O   1 
ATOM   2366 C  CB  . PRO A 1 322 ? 19.077  -5.443  56.042  1   12.636 ? 314  PRO A CB  1 
ATOM   2367 C  CG  . PRO A 1 322 ? 20.391  -4.685  55.755  1   11.739 ? 314  PRO A CG  1 
ATOM   2368 C  CD  . PRO A 1 322 ? 21.163  -5.513  54.701  1   13.222 ? 314  PRO A CD  1 
ATOM   2369 N  N   . ILE A 1 323 ? 17.228  -5.93   52.885  1   11.849 ? 315  ILE A N   1 
ATOM   2370 C  CA  . ILE A 1 323 ? 16.844  -5.349  51.6    1   11.682 ? 315  ILE A CA  1 
ATOM   2371 C  C   . ILE A 1 323 ? 15.912  -4.154  51.817  1   11.725 ? 315  ILE A C   1 
ATOM   2372 O  O   . ILE A 1 323 ? 16.16   -3.067  51.277  1   13.5   ? 315  ILE A O   1 
ATOM   2373 C  CB  . ILE A 1 323 ? 16.28   -6.416  50.645  1   12.269 ? 315  ILE A CB  1 
ATOM   2374 C  CG1 . ILE A 1 323 ? 17.34   -7.515  50.408  1   14.468 ? 315  ILE A CG1 1 
ATOM   2375 C  CG2 . ILE A 1 323 ? 15.81   -5.764  49.339  1   12.66  ? 315  ILE A CG2 1 
ATOM   2376 C  CD1 . ILE A 1 323 ? 16.684  -8.767  49.807  1   14.19  ? 315  ILE A CD1 1 
ATOM   2377 N  N   . HIS A 1 324 ? 14.829  -4.352  52.57   1   12.196 ? 316  HIS A N   1 
ATOM   2378 C  CA  . HIS A 1 324 ? 13.845  -3.305  52.815  1   12.354 ? 316  HIS A CA  1 
ATOM   2379 C  C   . HIS A 1 324 ? 13.492  -3.271  54.299  1   13.481 ? 316  HIS A C   1 
ATOM   2380 O  O   . HIS A 1 324 ? 13.389  -4.327  54.953  1   13.466 ? 316  HIS A O   1 
ATOM   2381 C  CB  . HIS A 1 324 ? 12.54   -3.568  52.052  1   13.104 ? 316  HIS A CB  1 
ATOM   2382 C  CG  . HIS A 1 324 ? 12.648  -3.308  50.583  1   12.103 ? 316  HIS A CG  1 
ATOM   2383 N  ND1 . HIS A 1 324 ? 12.594  -4.334  49.645  1   12.341 ? 316  HIS A ND1 1 
ATOM   2384 C  CD2 . HIS A 1 324 ? 12.818  -2.155  49.895  1   11.718 ? 316  HIS A CD2 1 
ATOM   2385 C  CE1 . HIS A 1 324 ? 12.765  -3.767  48.418  1   11.774 ? 316  HIS A CE1 1 
ATOM   2386 N  NE2 . HIS A 1 324 ? 12.883  -2.458  48.54   1   11.827 ? 316  HIS A NE2 1 
ATOM   2387 N  N   . THR A 1 325 ? 13.184  -2.081  54.785  1   13.24  ? 317  THR A N   1 
ATOM   2388 C  CA  . THR A 1 325 ? 12.59   -1.92   56.104  1   13.236 ? 317  THR A CA  1 
ATOM   2389 C  C   . THR A 1 325 ? 11.077  -2.099  56.008  1   12.526 ? 317  THR A C   1 
ATOM   2390 O  O   . THR A 1 325 ? 10.437  -1.724  55.013  1   12.364 ? 317  THR A O   1 
ATOM   2391 C  CB  . THR A 1 325 ? 12.937  -0.576  56.755  1   12.039 ? 317  THR A CB  1 
ATOM   2392 O  OG1 . THR A 1 325 ? 12.432  0.431   55.877  1   12.213 ? 317  THR A OG1 1 
ATOM   2393 C  CG2 . THR A 1 325 ? 14.437  -0.4    56.942  1   12.861 ? 317  THR A CG2 1 
ATOM   2394 N  N   . ALA A 1 326 ? 10.482  -2.636  57.09   1   11.665 ? 318  ALA A N   1 
ATOM   2395 C  CA  . ALA A 1 326 ? 9.048   -2.454  57.3    1   11.071 ? 318  ALA A CA  1 
ATOM   2396 C  C   . ALA A 1 326 ? 8.805   -1.003  57.701  1   12.176 ? 318  ALA A C   1 
ATOM   2397 O  O   . ALA A 1 326 ? 8.374   -0.182  56.889  1   12.549 ? 318  ALA A O   1 
ATOM   2398 C  CB  . ALA A 1 326 ? 8.559   -3.482  58.331  1   12.101 ? 318  ALA A CB  1 
ATOM   2399 N  N   . SER A 1 327 ? 9.19    -0.661  58.93   1   12.554 ? 319  SER A N   1 
ATOM   2400 C  CA  . SER A 1 327 ? 9.3     0.722   59.329  1   12.38  ? 319  SER A CA  1 
ATOM   2401 C  C   . SER A 1 327 ? 10.198  0.768   60.571  1   13.039 ? 319  SER A C   1 
ATOM   2402 O  O   . SER A 1 327 ? 10.807  -0.249  60.966  1   13.445 ? 319  SER A O   1 
ATOM   2403 C  CB  . SER A 1 327 ? 7.951   1.409   59.495  1   12.793 ? 319  SER A CB  1 
ATOM   2404 O  OG  . SER A 1 327 ? 8.152   2.824   59.519  1   13.229 ? 319  SER A OG  1 
ATOM   2405 N  N   . GLY A 1 328 ? 10.254  1.947   61.181  1   12.374 ? 320  GLY A N   1 
ATOM   2406 C  CA  . GLY A 1 328 ? 10.965  2.123   62.433  1   12.477 ? 320  GLY A CA  1 
ATOM   2407 C  C   . GLY A 1 328 ? 10.144  2.951   63.415  1   13.436 ? 320  GLY A C   1 
ATOM   2408 O  O   . GLY A 1 328 ? 9.132   3.563   63.053  1   14.328 ? 320  GLY A O   1 
ATOM   2409 N  N   . PHE A 1 329 ? 10.665  2.95    64.655  1   13.296 ? 321  PHE A N   1 
ATOM   2410 C  CA  . PHE A 1 329 ? 10.072  3.824   65.67   1   12.944 ? 321  PHE A CA  1 
ATOM   2411 C  C   . PHE A 1 329 ? 11.078  3.959   66.808  1   14.408 ? 321  PHE A C   1 
ATOM   2412 O  O   . PHE A 1 329 ? 12.16   3.347   66.79   1   14.924 ? 321  PHE A O   1 
ATOM   2413 C  CB  . PHE A 1 329 ? 8.714   3.314   66.161  1   14.121 ? 321  PHE A CB  1 
ATOM   2414 C  CG  . PHE A 1 329 ? 8.762   2.03    66.976  1   16.191 ? 321  PHE A CG  1 
ATOM   2415 C  CD1 . PHE A 1 329 ? 8.775   0.802   66.312  1   14.593 ? 321  PHE A CD1 1 
ATOM   2416 C  CD2 . PHE A 1 329 ? 8.725   2.03    68.383  1   17.829 ? 321  PHE A CD2 1 
ATOM   2417 C  CE1 . PHE A 1 329 ? 8.769   -0.401  67      1   15.305 ? 321  PHE A CE1 1 
ATOM   2418 C  CE2 . PHE A 1 329 ? 8.725   0.819   69.09   1   16.592 ? 321  PHE A CE2 1 
ATOM   2419 C  CZ  . PHE A 1 329 ? 8.775   -0.382  68.408  1   16.592 ? 321  PHE A CZ  1 
ATOM   2420 N  N   . GLU A 1 330 ? 10.722  4.809   67.808  1   15.28  ? 322  GLU A N   1 
ATOM   2421 C  CA  . GLU A 1 330 ? 11.565  4.879   69.006  1   16.173 ? 322  GLU A CA  1 
ATOM   2422 C  C   . GLU A 1 330 ? 10.802  4.28    70.184  1   15.356 ? 322  GLU A C   1 
ATOM   2423 O  O   . GLU A 1 330 ? 9.635   4.626   70.383  1   16.728 ? 322  GLU A O   1 
ATOM   2424 C  CB  . GLU A 1 330 ? 11.924  6.35    69.245  1   16.172 ? 322  GLU A CB  1 
ATOM   2425 C  CG  . GLU A 1 330 ? 13.024  6.827   68.282  1   17.129 ? 322  GLU A CG  1 
ATOM   2426 C  CD  . GLU A 1 330 ? 13.036  8.34    68.149  1   18.929 ? 322  GLU A CD  1 
ATOM   2427 O  OE1 . GLU A 1 330 ? 13.068  9.048   69.192  1   23.598 ? 322  GLU A OE1 1 
ATOM   2428 O  OE2 . GLU A 1 330 ? 12.993  8.883   67.014  1   17.654 ? 322  GLU A OE2 1 
ATOM   2429 N  N   . ASP A 1 331 ? 11.481  3.423   70.943  1   17.58  ? 323  ASP A N   1 
ATOM   2430 C  CA  . ASP A 1 331 ? 10.838  2.711   72.063  1   16.483 ? 323  ASP A CA  1 
ATOM   2431 C  C   . ASP A 1 331 ? 10.714  3.676   73.265  1   18.117 ? 323  ASP A C   1 
ATOM   2432 O  O   . ASP A 1 331 ? 11.065  4.857   73.175  1   18.846 ? 323  ASP A O   1 
ATOM   2433 C  CB  . ASP A 1 331 ? 11.48   1.358   72.342  1   18.642 ? 323  ASP A CB  1 
ATOM   2434 C  CG  . ASP A 1 331 ? 12.836  1.398   73.015  1   17.46  ? 323  ASP A CG  1 
ATOM   2435 O  OD1 . ASP A 1 331 ? 13.289  2.512   73.397  1   17.318 ? 323  ASP A OD1 1 
ATOM   2436 O  OD2 . ASP A 1 331 ? 13.499  0.338   73.052  1   18.742 ? 323  ASP A OD2 1 
ATOM   2437 N  N   . GLU A 1 332 ? 10.245  3.136   74.393  1   20.928 ? 324  GLU A N   1 
ATOM   2438 C  CA  . GLU A 1 332 ? 10.023  3.945   75.592  1   21.981 ? 324  GLU A CA  1 
ATOM   2439 C  C   . GLU A 1 332 ? 11.331  4.488   76.179  1   23.138 ? 324  GLU A C   1 
ATOM   2440 O  O   . GLU A 1 332 ? 11.24   5.412   76.983  1   24.763 ? 324  GLU A O   1 
ATOM   2441 C  CB  . GLU A 1 332 ? 9.096   3.175   76.551  1   26.38  ? 324  GLU A CB  1 
ATOM   2442 C  CG  . GLU A 1 332 ? 9.73    1.931   77.183  1   34.32  ? 324  GLU A CG  1 
ATOM   2443 C  CD  . GLU A 1 332 ? 10.181  0.707   76.369  1   49.35  ? 324  GLU A CD  1 
ATOM   2444 O  OE1 . GLU A 1 332 ? 9.66    0.466   75.234  1   40.61  ? 324  GLU A OE1 1 
ATOM   2445 O  OE2 . GLU A 1 332 ? 11.128  0.028   76.858  1   60.327 ? 324  GLU A OE2 1 
ATOM   2446 N  N   . GLN A 1 333 ? 12.508  3.949   75.813  1   19.553 ? 325  GLN A N   1 
ATOM   2447 C  CA  . GLN A 1 333 ? 13.803  4.445   76.241  1   20.205 ? 325  GLN A CA  1 
ATOM   2448 C  C   . GLN A 1 333 ? 14.524  5.266   75.169  1   18.732 ? 325  GLN A C   1 
ATOM   2449 O  O   . GLN A 1 333 ? 15.7    5.6     75.33   1   23.168 ? 325  GLN A O   1 
ATOM   2450 C  CB  . GLN A 1 333 ? 14.72   3.272   76.576  1   22.71  ? 325  GLN A CB  1 
ATOM   2451 C  CG  . GLN A 1 333 ? 14.293  2.438   77.782  1   26.883 ? 325  GLN A CG  1 
ATOM   2452 C  CD  . GLN A 1 333 ? 15.242  1.282   77.964  1   26.378 ? 325  GLN A CD  1 
ATOM   2453 O  OE1 . GLN A 1 333 ? 16.416  1.492   78.296  1   28.652 ? 325  GLN A OE1 1 
ATOM   2454 N  NE2 . GLN A 1 333 ? 14.737  0.083   77.789  1   26.794 ? 325  GLN A NE2 1 
ATOM   2455 N  N   . GLY A 1 334 ? 13.813  5.602   74.083  1   18.182 ? 326  GLY A N   1 
ATOM   2456 C  CA  . GLY A 1 334 ? 14.359  6.416   72.997  1   18.73  ? 326  GLY A CA  1 
ATOM   2457 C  C   . GLY A 1 334 ? 15.219  5.597   72.009  1   18.539 ? 326  GLY A C   1 
ATOM   2458 O  O   . GLY A 1 334 ? 15.948  6.176   71.205  1   19.524 ? 326  GLY A O   1 
ATOM   2459 N  N   . ARG A 1 335 ? 15.191  4.266   72.116  1   16.723 ? 327  ARG A N   1 
ATOM   2460 C  CA  . ARG A 1 335 ? 16.027  3.439   71.252  1   16.766 ? 327  ARG A CA  1 
ATOM   2461 C  C   . ARG A 1 335 ? 15.315  3.313   69.899  1   15.589 ? 327  ARG A C   1 
ATOM   2462 O  O   . ARG A 1 335 ? 14.089  3.241   69.828  1   15.237 ? 327  ARG A O   1 
ATOM   2463 C  CB  . ARG A 1 335 ? 16.221  2.036   71.836  1   15.755 ? 327  ARG A CB  1 
ATOM   2464 C  CG  . ARG A 1 335 ? 16.972  2.17    73.176  1   17.483 ? 327  ARG A CG  1 
ATOM   2465 C  CD  . ARG A 1 335 ? 17.386  0.819   73.699  1   21.742 ? 327  ARG A CD  1 
ATOM   2466 N  NE  . ARG A 1 335 ? 16.204  0.023   74.013  1   20.488 ? 327  ARG A NE  1 
ATOM   2467 C  CZ  . ARG A 1 335 ? 16.263  -1.05   74.777  1   26.449 ? 327  ARG A CZ  1 
ATOM   2468 N  NH1 . ARG A 1 335 ? 17.439  -1.496  75.244  1   25.274 ? 327  ARG A NH1 1 
ATOM   2469 N  NH2 . ARG A 1 335 ? 15.145  -1.677  75.064  1   23.329 ? 327  ARG A NH2 1 
ATOM   2470 N  N   . ILE A 1 336 ? 16.127  3.338   68.818  1   13.79  ? 328  ILE A N   1 
ATOM   2471 C  CA  . ILE A 1 336 ? 15.596  3.146   67.459  1   14.439 ? 328  ILE A CA  1 
ATOM   2472 C  C   . ILE A 1 336 ? 15.376  1.66    67.211  1   13.813 ? 328  ILE A C   1 
ATOM   2473 O  O   . ILE A 1 336 ? 16.311  0.87    67.304  1   14.787 ? 328  ILE A O   1 
ATOM   2474 C  CB  . ILE A 1 336 ? 16.602  3.79    66.485  1   13.511 ? 328  ILE A CB  1 
ATOM   2475 C  CG1 . ILE A 1 336 ? 16.69   5.301   66.662  1   16.094 ? 328  ILE A CG1 1 
ATOM   2476 C  CG2 . ILE A 1 336 ? 16.183  3.452   65.037  1   15.067 ? 328  ILE A CG2 1 
ATOM   2477 C  CD1 . ILE A 1 336 ? 17.968  5.851   66.074  1   15.092 ? 328  ILE A CD1 1 
ATOM   2478 N  N   . ILE A 1 337 ? 14.13   1.318   66.856  1   13.665 ? 329  ILE A N   1 
ATOM   2479 C  CA  . ILE A 1 337 ? 13.749  -0.054  66.549  1   14.261 ? 329  ILE A CA  1 
ATOM   2480 C  C   . ILE A 1 337 ? 13.334  -0.069  65.078  1   13.319 ? 329  ILE A C   1 
ATOM   2481 O  O   . ILE A 1 337 ? 12.489  0.717   64.676  1   15.119 ? 329  ILE A O   1 
ATOM   2482 C  CB  . ILE A 1 337 ? 12.559  -0.484  67.433  1   14.281 ? 329  ILE A CB  1 
ATOM   2483 C  CG1 . ILE A 1 337 ? 12.804  -0.184  68.966  1   17.008 ? 329  ILE A CG1 1 
ATOM   2484 C  CG2 . ILE A 1 337 ? 12.174  -1.956  67.188  1   14.656 ? 329  ILE A CG2 1 
ATOM   2485 C  CD1 . ILE A 1 337 ? 14.034  -0.891  69.528  1   16.928 ? 329  ILE A CD1 1 
ATOM   2486 N  N   . ILE A 1 338 ? 13.945  -0.996  64.324  1   12.571 ? 330  ILE A N   1 
ATOM   2487 C  CA  . ILE A 1 338 ? 13.681  -1.087  62.879  1   13.005 ? 330  ILE A CA  1 
ATOM   2488 C  C   . ILE A 1 338 ? 13.521  -2.57   62.544  1   12.962 ? 330  ILE A C   1 
ATOM   2489 O  O   . ILE A 1 338 ? 14.364  -3.384  62.89   1   13.408 ? 330  ILE A O   1 
ATOM   2490 C  CB  . ILE A 1 338 ? 14.866  -0.5    62.064  1   12.846 ? 330  ILE A CB  1 
ATOM   2491 C  CG1 . ILE A 1 338 ? 15.062  1.004   62.389  1   15.138 ? 330  ILE A CG1 1 
ATOM   2492 C  CG2 . ILE A 1 338 ? 14.646  -0.731  60.553  1   12.909 ? 330  ILE A CG2 1 
ATOM   2493 C  CD1 . ILE A 1 338 ? 16.338  1.59    61.795  1   14.563 ? 330  ILE A CD1 1 
ATOM   2494 N  N   . ASP A 1 339 ? 12.45   -2.92   61.829  1   13.11  ? 331  ASP A N   1 
ATOM   2495 C  CA  . ASP A 1 339 ? 12.367  -4.279  61.289  1   13.295 ? 331  ASP A CA  1 
ATOM   2496 C  C   . ASP A 1 339 ? 12.72   -4.245  59.803  1   13.114 ? 331  ASP A C   1 
ATOM   2497 O  O   . ASP A 1 339 ? 12.383  -3.289  59.087  1   13.434 ? 331  ASP A O   1 
ATOM   2498 C  CB  . ASP A 1 339 ? 10.997  -4.933  61.48   1   13.911 ? 331  ASP A CB  1 
ATOM   2499 C  CG  . ASP A 1 339 ? 10.594  -5.257  62.912  1   14.528 ? 331  ASP A CG  1 
ATOM   2500 O  OD1 . ASP A 1 339 ? 11.32   -4.812  63.84   1   14.373 ? 331  ASP A OD1 1 
ATOM   2501 O  OD2 . ASP A 1 339 ? 9.556   -5.906  63.076  1   14.394 ? 331  ASP A OD2 1 
ATOM   2502 N  N   . SER A 1 340 ? 13.363  -5.321  59.348  1   12.565 ? 332  SER A N   1 
ATOM   2503 C  CA  . SER A 1 340 ? 13.719  -5.417  57.953  1   12.254 ? 332  SER A CA  1 
ATOM   2504 C  C   . SER A 1 340 ? 13.823  -6.854  57.528  1   12.419 ? 332  SER A C   1 
ATOM   2505 O  O   . SER A 1 340 ? 13.974  -7.76   58.352  1   13.289 ? 332  SER A O   1 
ATOM   2506 C  CB  . SER A 1 340 ? 15.047  -4.74   57.681  1   13.322 ? 332  SER A CB  1 
ATOM   2507 O  OG  . SER A 1 340 ? 16.174  -5.524  58.117  1   13.836 ? 332  SER A OG  1 
ATOM   2508 N  N   . SER A 1 341 ? 13.822  -7.072  56.206  1   12.714 ? 333  SER A N   1 
ATOM   2509 C  CA  . SER A 1 341 ? 14.321  -8.357  55.737  1   12.585 ? 333  SER A CA  1 
ATOM   2510 C  C   . SER A 1 341 ? 15.826  -8.467  56.009  1   13.396 ? 333  SER A C   1 
ATOM   2511 O  O   . SER A 1 341 ? 16.521  -7.449  56.204  1   13.427 ? 333  SER A O   1 
ATOM   2512 C  CB  . SER A 1 341 ? 14.003  -8.555  54.279  1   13.488 ? 333  SER A CB  1 
ATOM   2513 O  OG  . SER A 1 341 ? 14.625  -7.523  53.497  1   13.743 ? 333  SER A OG  1 
ATOM   2514 N  N   . LEU A 1 342 ? 16.299  -9.723  56.06   1   12.921 ? 334  LEU A N   1 
ATOM   2515 C  CA  . LEU A 1 342 ? 17.741  -9.964  56.164  1   12.756 ? 334  LEU A CA  1 
ATOM   2516 C  C   . LEU A 1 342 ? 18.089  -11.219 55.378  1   13.499 ? 334  LEU A C   1 
ATOM   2517 O  O   . LEU A 1 342 ? 17.699  -12.316 55.775  1   14.184 ? 334  LEU A O   1 
ATOM   2518 C  CB  . LEU A 1 342 ? 18.243  -10.07  57.605  1   13.719 ? 334  LEU A CB  1 
ATOM   2519 C  CG  . LEU A 1 342 ? 19.732  -10.391 57.774  1   14.522 ? 334  LEU A CG  1 
ATOM   2520 C  CD1 . LEU A 1 342 ? 20.616  -9.289  57.136  1   14.659 ? 334  LEU A CD1 1 
ATOM   2521 C  CD2 . LEU A 1 342 ? 20.005  -10.435 59.266  1   16.113 ? 334  LEU A CD2 1 
ATOM   2522 N  N   . VAL A 1 343 ? 18.862  -10.999 54.315  1   12.65  ? 335  VAL A N   1 
ATOM   2523 C  CA  . VAL A 1 343 ? 19.423  -12.131 53.55   1   12.617 ? 335  VAL A CA  1 
ATOM   2524 C  C   . VAL A 1 343 ? 20.885  -12.221 53.966  1   13.598 ? 335  VAL A C   1 
ATOM   2525 O  O   . VAL A 1 343 ? 21.599  -11.217 53.975  1   14.427 ? 335  VAL A O   1 
ATOM   2526 C  CB  . VAL A 1 343 ? 19.249  -11.948 52.044  1   13.255 ? 335  VAL A CB  1 
ATOM   2527 C  CG1 . VAL A 1 343 ? 19.943  -13.049 51.264  1   13.436 ? 335  VAL A CG1 1 
ATOM   2528 C  CG2 . VAL A 1 343 ? 17.764  -11.921 51.667  1   16.121 ? 335  VAL A CG2 1 
ATOM   2529 N  N   . HIS A 1 344 ? 21.308  -13.425 54.372  1   13.821 ? 336  HIS A N   1 
ATOM   2530 C  CA  . HIS A 1 344 ? 22.629  -13.631 54.969  1   14.788 ? 336  HIS A CA  1 
ATOM   2531 C  C   . HIS A 1 344 ? 23.67   -13.851 53.875  1   15.804 ? 336  HIS A C   1 
ATOM   2532 O  O   . HIS A 1 344 ? 24.389  -14.862 53.833  1   17.193 ? 336  HIS A O   1 
ATOM   2533 C  CB  . HIS A 1 344 ? 22.605  -14.822 55.933  1   15.862 ? 336  HIS A CB  1 
ATOM   2534 C  CG  . HIS A 1 344 ? 21.778  -14.49  57.125  1   17.333 ? 336  HIS A CG  1 
ATOM   2535 N  ND1 . HIS A 1 344 ? 22.302  -13.935 58.29   1   19.611 ? 336  HIS A ND1 1 
ATOM   2536 C  CD2 . HIS A 1 344 ? 20.444  -14.61  57.309  1   16.629 ? 336  HIS A CD2 1 
ATOM   2537 C  CE1 . HIS A 1 344 ? 21.285  -13.772 59.152  1   21.679 ? 336  HIS A CE1 1 
ATOM   2538 N  NE2 . HIS A 1 344 ? 20.162  -14.193 58.559  1   18.493 ? 336  HIS A NE2 1 
ATOM   2539 N  N   . GLY A 1 345 ? 23.762  -12.851 52.953  1   15.135 ? 337  GLY A N   1 
ATOM   2540 C  CA  . GLY A 1 345 ? 24.6    -12.978 51.763  1   13.396 ? 337  GLY A CA  1 
ATOM   2541 C  C   . GLY A 1 345 ? 24.033  -12.105 50.636  1   14.456 ? 337  GLY A C   1 
ATOM   2542 O  O   . GLY A 1 345 ? 23.19   -11.246 50.909  1   14.771 ? 337  GLY A O   1 
ATOM   2543 N  N   . ASN A 1 346 ? 24.432  -12.389 49.406  1   13.907 ? 338  ASN A N   1 
ATOM   2544 C  CA  . ASN A 1 346 ? 24.091  -11.5   48.301  1   15.022 ? 338  ASN A CA  1 
ATOM   2545 C  C   . ASN A 1 346 ? 22.775  -11.901 47.642  1   13.806 ? 338  ASN A C   1 
ATOM   2546 O  O   . ASN A 1 346 ? 22.701  -12.9   46.933  1   16.569 ? 338  ASN A O   1 
ATOM   2547 C  CB  . ASN A 1 346 ? 25.254  -11.421 47.319  1   13.185 ? 338  ASN A CB  1 
ATOM   2548 C  CG  . ASN A 1 346 ? 25.045  -10.373 46.256  1   15.408 ? 338  ASN A CG  1 
ATOM   2549 O  OD1 . ASN A 1 346 ? 24.068  -9.624  46.343  1   14.019 ? 338  ASN A OD1 1 
ATOM   2550 N  ND2 . ASN A 1 346 ? 25.925  -10.306 45.292  1   14.04  ? 338  ASN A ND2 1 
ATOM   2551 N  N   . ALA A 1 347 ? 21.732  -11.071 47.811  1   13.013 ? 339  ALA A N   1 
ATOM   2552 C  CA  . ALA A 1 347 ? 20.451  -11.278 47.132  1   13.801 ? 339  ALA A CA  1 
ATOM   2553 C  C   . ALA A 1 347 ? 20.426  -10.684 45.731  1   15.542 ? 339  ALA A C   1 
ATOM   2554 O  O   . ALA A 1 347 ? 19.413  -10.862 45.027  1   15.17  ? 339  ALA A O   1 
ATOM   2555 C  CB  . ALA A 1 347 ? 19.304  -10.697 47.969  1   15.379 ? 339  ALA A CB  1 
ATOM   2556 N  N   . PHE A 1 348 ? 21.479  -9.966  45.323  1   15.494 ? 340  PHE A N   1 
ATOM   2557 C  CA  . PHE A 1 348 ? 21.601  -9.49   43.941  1   14.064 ? 340  PHE A CA  1 
ATOM   2558 C  C   . PHE A 1 348 ? 22.862  -10.157 43.373  1   14.832 ? 340  PHE A C   1 
ATOM   2559 O  O   . PHE A 1 348 ? 23.889  -9.512  43.13   1   15.505 ? 340  PHE A O   1 
ATOM   2560 C  CB  . PHE A 1 348 ? 21.776  -7.967  43.927  1   14.528 ? 340  PHE A CB  1 
ATOM   2561 C  CG  . PHE A 1 348 ? 20.545  -7.072  44.008  1   14.803 ? 340  PHE A CG  1 
ATOM   2562 C  CD1 . PHE A 1 348 ? 19.255  -7.566  44.185  1   17.294 ? 340  PHE A CD1 1 
ATOM   2563 C  CD2 . PHE A 1 348 ? 20.718  -5.699  43.883  1   15.578 ? 340  PHE A CD2 1 
ATOM   2564 C  CE1 . PHE A 1 348 ? 18.148  -6.674  44.19   1   17.784 ? 340  PHE A CE1 1 
ATOM   2565 C  CE2 . PHE A 1 348 ? 19.641  -4.828  43.898  1   15.682 ? 340  PHE A CE2 1 
ATOM   2566 C  CZ  . PHE A 1 348 ? 18.363  -5.314  44.032  1   16.68  ? 340  PHE A CZ  1 
ATOM   2567 N  N   . PRO A 1 349 ? 22.818  -11.493 43.114  1   16.317 ? 341  PRO A N   1 
ATOM   2568 C  CA  . PRO A 1 349 ? 24.059  -12.166 42.687  1   15.504 ? 341  PRO A CA  1 
ATOM   2569 C  C   . PRO A 1 349 ? 24.579  -11.686 41.33   1   14.88  ? 341  PRO A C   1 
ATOM   2570 O  O   . PRO A 1 349 ? 25.753  -11.913 41.024  1   16.493 ? 341  PRO A O   1 
ATOM   2571 C  CB  . PRO A 1 349 ? 23.641  -13.67  42.662  1   15.965 ? 341  PRO A CB  1 
ATOM   2572 C  CG  . PRO A 1 349 ? 22.147  -13.635 42.52   1   16.617 ? 341  PRO A CG  1 
ATOM   2573 C  CD  . PRO A 1 349 ? 21.665  -12.413 43.33   1   15.804 ? 341  PRO A CD  1 
ATOM   2574 N  N   . PHE A 1 350 ? 23.721  -11.007 40.547  1   13.896 ? 342  PHE A N   1 
ATOM   2575 C  CA  . PHE A 1 350 ? 24.118  -10.39  39.3    1   16.596 ? 342  PHE A CA  1 
ATOM   2576 C  C   . PHE A 1 350 ? 25.068  -9.2    39.458  1   15.175 ? 342  PHE A C   1 
ATOM   2577 O  O   . PHE A 1 350 ? 25.619  -8.73   38.457  1   17.666 ? 342  PHE A O   1 
ATOM   2578 C  CB  . PHE A 1 350 ? 22.863  -10.064 38.474  1   14.228 ? 342  PHE A CB  1 
ATOM   2579 C  CG  . PHE A 1 350 ? 21.799  -9.34   39.291  1   16.337 ? 342  PHE A CG  1 
ATOM   2580 C  CD1 . PHE A 1 350 ? 21.817  -7.954  39.417  1   15.787 ? 342  PHE A CD1 1 
ATOM   2581 C  CD2 . PHE A 1 350 ? 20.758  -10.047 39.904  1   15.921 ? 342  PHE A CD2 1 
ATOM   2582 C  CE1 . PHE A 1 350 ? 20.832  -7.283  40.131  1   15.837 ? 342  PHE A CE1 1 
ATOM   2583 C  CE2 . PHE A 1 350 ? 19.79   -9.378  40.632  1   15.551 ? 342  PHE A CE2 1 
ATOM   2584 C  CZ  . PHE A 1 350 ? 19.803  -7.985  40.732  1   16.266 ? 342  PHE A CZ  1 
ATOM   2585 N  N   . PHE A 1 351 ? 25.295  -8.75   40.698  1   15.343 ? 343  PHE A N   1 
ATOM   2586 C  CA  . PHE A 1 351 ? 26.371  -7.808  40.998  1   14.774 ? 343  PHE A CA  1 
ATOM   2587 C  C   . PHE A 1 351 ? 27.328  -8.487  41.97   1   15.316 ? 343  PHE A C   1 
ATOM   2588 O  O   . PHE A 1 351 ? 27.341  -8.209  43.187  1   15.763 ? 343  PHE A O   1 
ATOM   2589 C  CB  . PHE A 1 351 ? 25.851  -6.478  41.595  1   14.434 ? 343  PHE A CB  1 
ATOM   2590 C  CG  . PHE A 1 351 ? 24.821  -5.718  40.75   1   14.264 ? 343  PHE A CG  1 
ATOM   2591 C  CD1 . PHE A 1 351 ? 24.862  -5.683  39.343  1   14.11  ? 343  PHE A CD1 1 
ATOM   2592 C  CD2 . PHE A 1 351 ? 23.834  -4.999  41.415  1   13.593 ? 343  PHE A CD2 1 
ATOM   2593 C  CE1 . PHE A 1 351 ? 23.879  -5.005  38.619  1   15.298 ? 343  PHE A CE1 1 
ATOM   2594 C  CE2 . PHE A 1 351 ? 22.863  -4.293  40.691  1   14.692 ? 343  PHE A CE2 1 
ATOM   2595 C  CZ  . PHE A 1 351 ? 22.896  -4.29   39.302  1   14.301 ? 343  PHE A CZ  1 
ATOM   2596 N  N   . PRO A 1 352 ? 28.165  -9.402  41.455  1   16.125 ? 344  PRO A N   1 
ATOM   2597 C  CA  . PRO A 1 352 ? 29.06   -10.177 42.327  1   15.355 ? 344  PRO A CA  1 
ATOM   2598 C  C   . PRO A 1 352 ? 30.205  -9.34   42.885  1   15.982 ? 344  PRO A C   1 
ATOM   2599 O  O   . PRO A 1 352 ? 30.42   -8.166  42.507  1   15.768 ? 344  PRO A O   1 
ATOM   2600 C  CB  . PRO A 1 352 ? 29.558  -11.271 41.344  1   16.185 ? 344  PRO A CB  1 
ATOM   2601 C  CG  . PRO A 1 352 ? 29.644  -10.531 40.026  1   15.706 ? 344  PRO A CG  1 
ATOM   2602 C  CD  . PRO A 1 352 ? 28.287  -9.77   40.028  1   15.488 ? 344  PRO A CD  1 
ATOM   2603 N  N   . PRO A 1 353 ? 31.022  -9.904  43.814  1   14.743 ? 345  PRO A N   1 
ATOM   2604 C  CA  . PRO A 1 353 ? 32.206  -9.192  44.27   1   14.636 ? 345  PRO A CA  1 
ATOM   2605 C  C   . PRO A 1 353 ? 33.238  -8.916  43.192  1   15.304 ? 345  PRO A C   1 
ATOM   2606 O  O   . PRO A 1 353 ? 33.206  -9.497  42.099  1   17.448 ? 345  PRO A O   1 
ATOM   2607 C  CB  . PRO A 1 353 ? 32.79   -10.209 45.291  1   15.668 ? 345  PRO A CB  1 
ATOM   2608 C  CG  . PRO A 1 353 ? 31.594  -11.009 45.74   1   14.887 ? 345  PRO A CG  1 
ATOM   2609 C  CD  . PRO A 1 353 ? 30.819  -11.222 44.45   1   15.835 ? 345  PRO A CD  1 
ATOM   2610 N  N   . ASP A 1 354 ? 34.173  -8.029  43.537  1   16.635 ? 346  ASP A N   1 
ATOM   2611 C  CA  . ASP A 1 354 ? 35.236  -7.624  42.654  1   21.165 ? 346  ASP A CA  1 
ATOM   2612 C  C   . ASP A 1 354 ? 36.37   -8.657  42.682  1   20.883 ? 346  ASP A C   1 
ATOM   2613 O  O   . ASP A 1 354 ? 36.824  -9.055  41.608  1   25.202 ? 346  ASP A O   1 
ATOM   2614 C  CB  . ASP A 1 354 ? 35.674  -6.253  43.161  1   26.475 ? 346  ASP A CB  1 
ATOM   2615 C  CG  . ASP A 1 354 ? 36.484  -5.457  42.172  1   34.278 ? 346  ASP A CG  1 
ATOM   2616 O  OD1 . ASP A 1 354 ? 35.911  -4.935  41.208  1   27.43  ? 346  ASP A OD1 1 
ATOM   2617 O  OD2 . ASP A 1 354 ? 37.707  -5.468  42.352  1   45.583 ? 346  ASP A OD2 1 
ATOM   2618 N  N   . SER A 1 355 ? 36.746  -9.139  43.883  1   20.076 ? 347  SER A N   1 
ATOM   2619 C  CA  . SER A 1 355 ? 37.967  -9.939  43.979  1   18.954 ? 347  SER A CA  1 
ATOM   2620 C  C   . SER A 1 355 ? 37.668  -11.391 43.626  1   21.207 ? 347  SER A C   1 
ATOM   2621 O  O   . SER A 1 355 ? 36.542  -11.884 43.832  1   20.344 ? 347  SER A O   1 
ATOM   2622 C  CB  . SER A 1 355 ? 38.592  -9.83   45.355  1   21.382 ? 347  SER A CB  1 
ATOM   2623 O  OG  . SER A 1 355 ? 37.872  -10.656 46.28   1   23.657 ? 347  SER A OG  1 
ATOM   2624 N  N   . ASP A 1 356 ? 38.695  -12.097 43.134  1   22.62  ? 348  ASP A N   1 
ATOM   2625 C  CA  . ASP A 1 356 ? 38.545  -13.512 42.817  1   23.602 ? 348  ASP A CA  1 
ATOM   2626 C  C   . ASP A 1 356 ? 38.087  -14.354 44.002  1   18.888 ? 348  ASP A C   1 
ATOM   2627 O  O   . ASP A 1 356 ? 37.171  -15.17  43.846  1   20.498 ? 348  ASP A O   1 
ATOM   2628 C  CB  . ASP A 1 356 ? 39.824  -14.06  42.201  1   32.83  ? 348  ASP A CB  1 
ATOM   2629 C  CG  . ASP A 1 356 ? 40.192  -13.451 40.852  1   39.64  ? 348  ASP A CG  1 
ATOM   2630 O  OD1 . ASP A 1 356 ? 39.298  -12.907 40.148  1   38.743 ? 348  ASP A OD1 1 
ATOM   2631 O  OD2 . ASP A 1 356 ? 41.394  -13.493 40.526  1   46.651 ? 348  ASP A OD2 1 
ATOM   2632 N  N   . GLU A 1 357 ? 38.681  -14.141 45.186  1   18.109 ? 349  GLU A N   1 
ATOM   2633 C  CA  . GLU A 1 357 ? 38.356  -14.952 46.348  1   18.759 ? 349  GLU A CA  1 
ATOM   2634 C  C   . GLU A 1 357 ? 36.891  -14.768 46.752  1   18.668 ? 349  GLU A C   1 
ATOM   2635 O  O   . GLU A 1 357 ? 36.206  -15.73  47.101  1   19.328 ? 349  GLU A O   1 
ATOM   2636 C  CB  . GLU A 1 357 ? 39.306  -14.592 47.49   1   24.199 ? 349  GLU A CB  1 
ATOM   2637 C  CG  . GLU A 1 357 ? 39.044  -15.337 48.79   1   40.22  ? 349  GLU A CG  1 
ATOM   2638 C  CD  . GLU A 1 357 ? 39.988  -15.001 49.923  1   58.915 ? 349  GLU A CD  1 
ATOM   2639 O  OE1 . GLU A 1 357 ? 40.909  -14.149 49.789  1   61.399 ? 349  GLU A OE1 1 
ATOM   2640 O  OE2 . GLU A 1 357 ? 39.769  -15.66  50.964  1   69.958 ? 349  GLU A OE2 1 
ATOM   2641 N  N   . GLN A 1 358 ? 36.42   -13.501 46.752  1   17.416 ? 350  GLN A N   1 
ATOM   2642 C  CA  . GLN A 1 358 ? 35.042  -13.271 47.176  1   16.062 ? 350  GLN A CA  1 
ATOM   2643 C  C   . GLN A 1 358 ? 34.052  -13.803 46.134  1   15.154 ? 350  GLN A C   1 
ATOM   2644 O  O   . GLN A 1 358 ? 33.009  -14.299 46.53   1   16.06  ? 350  GLN A O   1 
ATOM   2645 C  CB  . GLN A 1 358 ? 34.842  -11.783 47.446  1   16.666 ? 350  GLN A CB  1 
ATOM   2646 C  CG  . GLN A 1 358 ? 35.473  -11.294 48.753  1   16.59  ? 350  GLN A CG  1 
ATOM   2647 C  CD  . GLN A 1 358 ? 34.847  -9.99   49.217  1   17.169 ? 350  GLN A CD  1 
ATOM   2648 O  OE1 . GLN A 1 358 ? 33.685  -9.715  48.885  1   16.927 ? 350  GLN A OE1 1 
ATOM   2649 N  NE2 . GLN A 1 358 ? 35.63   -9.138  49.849  1   16.676 ? 350  GLN A NE2 1 
ATOM   2650 N  N   . LYS A 1 359 ? 34.384  -13.719 44.838  1   16.047 ? 351  LYS A N   1 
ATOM   2651 C  CA  . LYS A 1 359 ? 33.527  -14.267 43.804  1   16.947 ? 351  LYS A CA  1 
ATOM   2652 C  C   . LYS A 1 359 ? 33.372  -15.773 44.028  1   15.785 ? 351  LYS A C   1 
ATOM   2653 O  O   . LYS A 1 359 ? 32.271  -16.3   43.85   1   16.684 ? 351  LYS A O   1 
ATOM   2654 C  CB  . LYS A 1 359 ? 34.091  -14.07  42.394  1   19.456 ? 351  LYS A CB  1 
ATOM   2655 C  CG  . LYS A 1 359 ? 34.021  -12.644 41.854  1   22.62  ? 351  LYS A CG  1 
ATOM   2656 C  CD  . LYS A 1 359 ? 34.687  -12.749 40.477  1   26.804 ? 351  LYS A CD  1 
ATOM   2657 C  CE  . LYS A 1 359 ? 34.738  -11.493 39.74   1   43.774 ? 351  LYS A CE  1 
ATOM   2658 N  NZ  . LYS A 1 359 ? 35.672  -11.727 38.636  1   50.76  ? 351  LYS A NZ  1 
ATOM   2659 N  N   . LYS A 1 360 ? 34.479  -16.457 44.403  1   16.638 ? 352  LYS A N   1 
ATOM   2660 C  CA  . LYS A 1 360 ? 34.393  -17.904 44.612  1   16.562 ? 352  LYS A CA  1 
ATOM   2661 C  C   . LYS A 1 360 ? 33.479  -18.242 45.789  1   15.677 ? 352  LYS A C   1 
ATOM   2662 O  O   . LYS A 1 360 ? 32.668  -19.179 45.726  1   18.259 ? 352  LYS A O   1 
ATOM   2663 C  CB  . LYS A 1 360 ? 35.792  -18.506 44.824  1   16.647 ? 352  LYS A CB  1 
ATOM   2664 C  CG  . LYS A 1 360 ? 36.575  -18.442 43.522  1   18.909 ? 352  LYS A CG  1 
ATOM   2665 C  CD  . LYS A 1 360 ? 37.879  -19.259 43.582  1   18.831 ? 352  LYS A CD  1 
ATOM   2666 C  CE  . LYS A 1 360 ? 38.843  -18.92  42.467  1   19.593 ? 352  LYS A CE  1 
ATOM   2667 N  NZ  . LYS A 1 360 ? 38.31   -18.874 41.097  1   23.385 ? 352  LYS A NZ  1 
ATOM   2668 N  N   . LYS A 1 361 ? 33.514  -17.398 46.847  1   15.455 ? 353  LYS A N   1 
ATOM   2669 C  CA  . LYS A 1 361 ? 32.598  -17.59  47.954  1   15.342 ? 353  LYS A CA  1 
ATOM   2670 C  C   . LYS A 1 361 ? 31.117  -17.449 47.53   1   15.731 ? 353  LYS A C   1 
ATOM   2671 O  O   . LYS A 1 361 ? 30.254  -18.24  47.928  1   15.282 ? 353  LYS A O   1 
ATOM   2672 C  CB  . LYS A 1 361 ? 32.977  -16.653 49.112  1   16.39  ? 353  LYS A CB  1 
ATOM   2673 C  CG  . LYS A 1 361 ? 31.975  -16.765 50.278  1   18.032 ? 353  LYS A CG  1 
ATOM   2674 C  CD  . LYS A 1 361 ? 32.359  -15.853 51.458  1   20.199 ? 353  LYS A CD  1 
ATOM   2675 C  CE  . LYS A 1 361 ? 31.296  -15.775 52.531  1   23.21  ? 353  LYS A CE  1 
ATOM   2676 N  NZ  . LYS A 1 361 ? 30.822  -17.052 53.104  1   22.413 ? 353  LYS A NZ  1 
ATOM   2677 N  N   . GLN A 1 362 ? 30.829  -16.417 46.733  1   15.04  ? 354  GLN A N   1 
ATOM   2678 C  CA  . GLN A 1 362 ? 29.433  -16.238 46.347  1   16.271 ? 354  GLN A CA  1 
ATOM   2679 C  C   . GLN A 1 362 ? 28.915  -17.466 45.582  1   15.757 ? 354  GLN A C   1 
ATOM   2680 O  O   . GLN A 1 362 ? 27.805  -17.901 45.822  1   17.305 ? 354  GLN A O   1 
ATOM   2681 C  CB  . GLN A 1 362 ? 29.253  -14.953 45.533  1   15.729 ? 354  GLN A CB  1 
ATOM   2682 C  CG  . GLN A 1 362 ? 27.804  -14.797 45.054  1   17.115 ? 354  GLN A CG  1 
ATOM   2683 C  CD  . GLN A 1 362 ? 27.578  -13.527 44.261  1   17.14  ? 354  GLN A CD  1 
ATOM   2684 O  OE1 . GLN A 1 362 ? 27.817  -12.436 44.803  1   17.543 ? 354  GLN A OE1 1 
ATOM   2685 N  NE2 . GLN A 1 362 ? 27.135  -13.682 43.018  1   18.063 ? 354  GLN A NE2 1 
ATOM   2686 N  N   . GLU A 1 363 ? 29.751  -17.981 44.67   1   17.458 ? 355  GLU A N   1 
ATOM   2687 C  CA  . GLU A 1 363 ? 29.34   -19.105 43.843  1   19.259 ? 355  GLU A CA  1 
ATOM   2688 C  C   . GLU A 1 363 ? 29.173  -20.339 44.723  1   17.366 ? 355  GLU A C   1 
ATOM   2689 O  O   . GLU A 1 363 ? 28.131  -21.016 44.633  1   21.555 ? 355  GLU A O   1 
ATOM   2690 C  CB  . GLU A 1 363 ? 30.445  -19.311 42.807  1   24.367 ? 355  GLU A CB  1 
ATOM   2691 C  CG  . GLU A 1 363 ? 30.225  -18.685 41.437  1   31.029 ? 355  GLU A CG  1 
ATOM   2692 C  CD  . GLU A 1 363 ? 30.713  -19.627 40.32   1   28.679 ? 355  GLU A CD  1 
ATOM   2693 O  OE1 . GLU A 1 363 ? 31.937  -19.558 40.105  1   35.491 ? 355  GLU A OE1 1 
ATOM   2694 O  OE2 . GLU A 1 363 ? 29.931  -20.456 39.739  1   32.045 ? 355  GLU A OE2 1 
ATOM   2695 N  N   . ALA A 1 364 ? 30.11   -20.553 45.65   1   16.486 ? 356  ALA A N   1 
ATOM   2696 C  CA  . ALA A 1 364 ? 30.021  -21.706 46.537  1   19.527 ? 356  ALA A CA  1 
ATOM   2697 C  C   . ALA A 1 364 ? 28.784  -21.664 47.436  1   21.796 ? 356  ALA A C   1 
ATOM   2698 O  O   . ALA A 1 364 ? 28.113  -22.688 47.654  1   21.671 ? 356  ALA A O   1 
ATOM   2699 C  CB  . ALA A 1 364 ? 31.285  -21.854 47.377  1   19.879 ? 356  ALA A CB  1 
ATOM   2700 N  N   . ASP A 1 365 ? 28.468  -20.48  47.962  1   19.108 ? 357  ASP A N   1 
ATOM   2701 C  CA  . ASP A 1 365 ? 27.364  -20.387 48.917  1   19.933 ? 357  ASP A CA  1 
ATOM   2702 C  C   . ASP A 1 365 ? 25.984  -20.533 48.286  1   20.633 ? 357  ASP A C   1 
ATOM   2703 O  O   . ASP A 1 365 ? 25.051  -20.942 49.007  1   23.321 ? 357  ASP A O   1 
ATOM   2704 C  CB  . ASP A 1 365 ? 27.424  -19.08  49.712  1   20.551 ? 357  ASP A CB  1 
ATOM   2705 C  CG  . ASP A 1 365 ? 28.597  -19.004 50.695  1   23.168 ? 357  ASP A CG  1 
ATOM   2706 O  OD1 . ASP A 1 365 ? 29.261  -20.025 50.945  1   25.471 ? 357  ASP A OD1 1 
ATOM   2707 O  OD2 . ASP A 1 365 ? 28.851  -17.916 51.228  1   20.802 ? 357  ASP A OD2 1 
ATOM   2708 N  N   . GLY A 1 366 ? 25.807  -20.056 47.043  1   20.307 ? 358  GLY A N   1 
ATOM   2709 C  CA  . GLY A 1 366 ? 24.501  -20.079 46.384  1   19.115 ? 358  GLY A CA  1 
ATOM   2710 C  C   . GLY A 1 366 ? 23.473  -19.216 47.143  1   20.21  ? 358  GLY A C   1 
ATOM   2711 O  O   . GLY A 1 366 ? 23.833  -18.236 47.809  1   20.904 ? 358  GLY A O   1 
ATOM   2712 N  N   . THR A 1 367 ? 22.202  -19.674 47.146  1   20.709 ? 359  THR A N   1 
ATOM   2713 C  CA  . THR A 1 367 ? 21.147  -18.926 47.827  1   18.845 ? 359  THR A CA  1 
ATOM   2714 C  C   . THR A 1 367 ? 21.376  -18.866 49.351  1   18.01  ? 359  THR A C   1 
ATOM   2715 O  O   . THR A 1 367 ? 21.334  -19.908 50.035  1   18.655 ? 359  THR A O   1 
ATOM   2716 C  CB  . THR A 1 367 ? 19.791  -19.549 47.514  1   18.76  ? 359  THR A CB  1 
ATOM   2717 O  OG1 . THR A 1 367 ? 19.684  -19.43  46.102  1   20.724 ? 359  THR A OG1 1 
ATOM   2718 C  CG2 . THR A 1 367 ? 18.653  -18.788 48.191  1   20.285 ? 359  THR A CG2 1 
ATOM   2719 N  N   . PRO A 1 368 ? 21.521  -17.657 49.957  1   17.662 ? 360  PRO A N   1 
ATOM   2720 C  CA  . PRO A 1 368 ? 21.667  -17.532 51.404  1   16.265 ? 360  PRO A CA  1 
ATOM   2721 C  C   . PRO A 1 368 ? 20.37   -17.743 52.191  1   15.736 ? 360  PRO A C   1 
ATOM   2722 O  O   . PRO A 1 368 ? 19.273  -17.722 51.62   1   16.8   ? 360  PRO A O   1 
ATOM   2723 C  CB  . PRO A 1 368 ? 22.181  -16.076 51.608  1   16.767 ? 360  PRO A CB  1 
ATOM   2724 C  CG  . PRO A 1 368 ? 22.57   -15.607 50.236  1   17.81  ? 360  PRO A CG  1 
ATOM   2725 C  CD  . PRO A 1 368 ? 21.645  -16.341 49.278  1   17.453 ? 360  PRO A CD  1 
ATOM   2726 N  N   . LYS A 1 369 ? 20.508  -17.992 53.502  1   16.434 ? 361  LYS A N   1 
ATOM   2727 C  CA  . LYS A 1 369 ? 19.406  -17.942 54.461  1   16.886 ? 361  LYS A CA  1 
ATOM   2728 C  C   . LYS A 1 369 ? 18.765  -16.534 54.439  1   15.5   ? 361  LYS A C   1 
ATOM   2729 O  O   . LYS A 1 369 ? 19.449  -15.531 54.224  1   16.364 ? 361  LYS A O   1 
ATOM   2730 C  CB  . LYS A 1 369 ? 19.953  -18.236 55.868  1   20.792 ? 361  LYS A CB  1 
ATOM   2731 C  CG  . LYS A 1 369 ? 18.954  -18.36  57.048  1   28.358 ? 361  LYS A CG  1 
ATOM   2732 C  CD  . LYS A 1 369 ? 19.578  -18.75  58.401  1   37.928 ? 361  LYS A CD  1 
ATOM   2733 C  CE  . LYS A 1 369 ? 20.473  -17.667 59.032  1   45.214 ? 361  LYS A CE  1 
ATOM   2734 N  NZ  . LYS A 1 369 ? 21.151  -17.919 60.314  1   47.71  ? 361  LYS A NZ  1 
ATOM   2735 N  N   . ALA A 1 370 ? 17.448  -16.509 54.578  1   15.273 ? 362  ALA A N   1 
ATOM   2736 C  CA  . ALA A 1 370 ? 16.699  -15.265 54.506  1   14.723 ? 362  ALA A CA  1 
ATOM   2737 C  C   . ALA A 1 370 ? 15.609  -15.269 55.573  1   14.275 ? 362  ALA A C   1 
ATOM   2738 O  O   . ALA A 1 370 ? 14.923  -16.278 55.791  1   14.972 ? 362  ALA A O   1 
ATOM   2739 C  CB  . ALA A 1 370 ? 16.106  -15.12  53.121  1   14.624 ? 362  ALA A CB  1 
ATOM   2740 N  N   . GLN A 1 371 ? 15.502  -14.141 56.299  1   14.347 ? 363  GLN A N   1 
ATOM   2741 C  CA  . GLN A 1 371 ? 14.612  -14.033 57.45   1   14.446 ? 363  GLN A CA  1 
ATOM   2742 C  C   . GLN A 1 371 ? 14.026  -12.614 57.5    1   14.252 ? 363  GLN A C   1 
ATOM   2743 O  O   . GLN A 1 371 ? 14.378  -11.745 56.676  1   13.616 ? 363  GLN A O   1 
ATOM   2744 C  CB  . GLN A 1 371 ? 15.457  -14.199 58.73   1   13.587 ? 363  GLN A CB  1 
ATOM   2745 C  CG  . GLN A 1 371 ? 16.084  -15.588 58.841  1   16.809 ? 363  GLN A CG  1 
ATOM   2746 C  CD  . GLN A 1 371 ? 17.009  -15.68  60.032  1   17.282 ? 363  GLN A CD  1 
ATOM   2747 O  OE1 . GLN A 1 371 ? 17.907  -14.846 60.219  1   18.483 ? 363  GLN A OE1 1 
ATOM   2748 N  NE2 . GLN A 1 371 ? 16.87   -16.783 60.774  1   20.349 ? 363  GLN A NE2 1 
ATOM   2749 N  N   . PHE A 1 372 ? 13.16   -12.365 58.493  1   13.997 ? 364  PHE A N   1 
ATOM   2750 C  CA  . PHE A 1 372 ? 12.671  -11.033 58.822  1   13.705 ? 364  PHE A CA  1 
ATOM   2751 C  C   . PHE A 1 372 ? 13.122  -10.763 60.251  1   15.029 ? 364  PHE A C   1 
ATOM   2752 O  O   . PHE A 1 372 ? 12.859  -11.601 61.114  1   14.14  ? 364  PHE A O   1 
ATOM   2753 C  CB  . PHE A 1 372 ? 11.142  -11.025 58.683  1   13.911 ? 364  PHE A CB  1 
ATOM   2754 C  CG  . PHE A 1 372 ? 10.473  -9.67   58.872  1   14.7   ? 364  PHE A CG  1 
ATOM   2755 C  CD1 . PHE A 1 372 ? 10.608  -8.678  57.883  1   14.676 ? 364  PHE A CD1 1 
ATOM   2756 C  CD2 . PHE A 1 372 ? 9.709   -9.386  60.015  1   14.688 ? 364  PHE A CD2 1 
ATOM   2757 C  CE1 . PHE A 1 372 ? 10.005  -7.417  58.095  1   15.457 ? 364  PHE A CE1 1 
ATOM   2758 C  CE2 . PHE A 1 372 ? 9.098   -8.133  60.212  1   14.892 ? 364  PHE A CE2 1 
ATOM   2759 C  CZ  . PHE A 1 372 ? 9.249   -7.152  59.247  1   13.5   ? 364  PHE A CZ  1 
ATOM   2760 N  N   . VAL A 1 373 ? 13.756  -9.618  60.495  1   14.228 ? 365  VAL A N   1 
ATOM   2761 C  CA  . VAL A 1 373 ? 14.46   -9.377  61.757  1   12.19  ? 365  VAL A CA  1 
ATOM   2762 C  C   . VAL A 1 373 ? 14.165  -7.988  62.331  1   14.675 ? 365  VAL A C   1 
ATOM   2763 O  O   . VAL A 1 373 ? 13.699  -7.092  61.627  1   14.27  ? 365  VAL A O   1 
ATOM   2764 C  CB  . VAL A 1 373 ? 15.997  -9.625  61.603  1   13.899 ? 365  VAL A CB  1 
ATOM   2765 C  CG1 . VAL A 1 373 ? 16.28   -11.015 60.998  1   14.698 ? 365  VAL A CG1 1 
ATOM   2766 C  CG2 . VAL A 1 373 ? 16.675  -8.517  60.775  1   15.596 ? 365  VAL A CG2 1 
ATOM   2767 N  N   . ARG A 1 374 ? 14.614  -7.773  63.581  1   13.291 ? 366  ARG A N   1 
ATOM   2768 C  CA  . ARG A 1 374 ? 14.421  -6.527  64.293  1   13.642 ? 366  ARG A CA  1 
ATOM   2769 C  C   . ARG A 1 374 ? 15.758  -6.054  64.847  1   13.866 ? 366  ARG A C   1 
ATOM   2770 O  O   . ARG A 1 374 ? 16.446  -6.769  65.597  1   15.661 ? 366  ARG A O   1 
ATOM   2771 C  CB  . ARG A 1 374 ? 13.476  -6.771  65.492  1   12.955 ? 366  ARG A CB  1 
ATOM   2772 C  CG  . ARG A 1 374 ? 13.261  -5.524  66.349  1   13.624 ? 366  ARG A CG  1 
ATOM   2773 C  CD  . ARG A 1 374 ? 12.01   -5.592  67.234  1   14.375 ? 366  ARG A CD  1 
ATOM   2774 N  NE  . ARG A 1 374 ? 10.81   -5.784  66.402  1   14.575 ? 366  ARG A NE  1 
ATOM   2775 C  CZ  . ARG A 1 374 ? 9.825   -6.633  66.645  1   17.676 ? 366  ARG A CZ  1 
ATOM   2776 N  NH1 . ARG A 1 374 ? 9.672   -7.181  67.877  1   19.074 ? 366  ARG A NH1 1 
ATOM   2777 N  NH2 . ARG A 1 374 ? 8.963   -6.914  65.691  1   15.811 ? 366  ARG A NH2 1 
ATOM   2778 N  N   . TRP A 1 375 ? 16.078  -4.808  64.517  1   13.628 ? 367  TRP A N   1 
ATOM   2779 C  CA  . TRP A 1 375 ? 17.301  -4.122  64.928  1   13.378 ? 367  TRP A CA  1 
ATOM   2780 C  C   . TRP A 1 375 ? 17.007  -3.149  66.057  1   14.146 ? 367  TRP A C   1 
ATOM   2781 O  O   . TRP A 1 375 ? 15.945  -2.524  66.074  1   14.736 ? 367  TRP A O   1 
ATOM   2782 C  CB  . TRP A 1 375 ? 17.893  -3.292  63.772  1   13.859 ? 367  TRP A CB  1 
ATOM   2783 C  CG  . TRP A 1 375 ? 18.077  -4.072  62.493  1   13.6   ? 367  TRP A CG  1 
ATOM   2784 C  CD1 . TRP A 1 375 ? 17.168  -4.261  61.487  1   13.64  ? 367  TRP A CD1 1 
ATOM   2785 C  CD2 . TRP A 1 375 ? 19.257  -4.783  62.097  1   14.788 ? 367  TRP A CD2 1 
ATOM   2786 N  NE1 . TRP A 1 375 ? 17.708  -5.062  60.49   1   13.609 ? 367  TRP A NE1 1 
ATOM   2787 C  CE2 . TRP A 1 375 ? 18.987  -5.391  60.852  1   14.002 ? 367  TRP A CE2 1 
ATOM   2788 C  CE3 . TRP A 1 375 ? 20.515  -4.96   62.712  1   13.786 ? 367  TRP A CE3 1 
ATOM   2789 C  CZ2 . TRP A 1 375 ? 19.926  -6.17   60.167  1   14.797 ? 367  TRP A CZ2 1 
ATOM   2790 C  CZ3 . TRP A 1 375 ? 21.449  -5.719  62.025  1   16.839 ? 367  TRP A CZ3 1 
ATOM   2791 C  CH2 . TRP A 1 375 ? 21.161  -6.324  60.789  1   16.003 ? 367  TRP A CH2 1 
ATOM   2792 N  N   . THR A 1 376 ? 17.997  -3.005  66.985  1   14.537 ? 368  THR A N   1 
ATOM   2793 C  CA  . THR A 1 376 ? 17.931  -2.033  68.06   1   15.778 ? 368  THR A CA  1 
ATOM   2794 C  C   . THR A 1 376 ? 19.185  -1.145  68.007  1   15.232 ? 368  THR A C   1 
ATOM   2795 O  O   . THR A 1 376 ? 20.312  -1.658  68.144  1   17.033 ? 368  THR A O   1 
ATOM   2796 C  CB  . THR A 1 376 ? 17.843  -2.724  69.424  1   16.565 ? 368  THR A CB  1 
ATOM   2797 O  OG1 . THR A 1 376 ? 16.636  -3.475  69.465  1   17.118 ? 368  THR A OG1 1 
ATOM   2798 C  CG2 . THR A 1 376 ? 17.761  -1.688  70.548  1   17.243 ? 368  THR A CG2 1 
ATOM   2799 N  N   . ILE A 1 377 ? 18.982  0.159   67.768  1   15.52  ? 369  ILE A N   1 
ATOM   2800 C  CA  . ILE A 1 377 ? 20.076  1.113   67.79   1   15.242 ? 369  ILE A CA  1 
ATOM   2801 C  C   . ILE A 1 377 ? 19.79   2.076   68.938  1   15.817 ? 369  ILE A C   1 
ATOM   2802 O  O   . ILE A 1 377 ? 18.921  2.954   68.834  1   16.408 ? 369  ILE A O   1 
ATOM   2803 C  CB  . ILE A 1 377 ? 20.161  1.886   66.452  1   16.928 ? 369  ILE A CB  1 
ATOM   2804 C  CG1 . ILE A 1 377 ? 20.386  0.902   65.296  1   15.649 ? 369  ILE A CG1 1 
ATOM   2805 C  CG2 . ILE A 1 377 ? 21.272  2.947   66.572  1   17.341 ? 369  ILE A CG2 1 
ATOM   2806 C  CD1 . ILE A 1 377 ? 20.313  1.559   63.919  1   16.6   ? 369  ILE A CD1 1 
ATOM   2807 N  N   . ASP A 1 378 ? 20.583  1.913   70.018  1   16.742 ? 370  ASP A N   1 
ATOM   2808 C  CA  . ASP A 1 378 ? 20.402  2.771   71.188  1   17.844 ? 370  ASP A CA  1 
ATOM   2809 C  C   . ASP A 1 378 ? 21.336  3.978   71.077  1   18.007 ? 370  ASP A C   1 
ATOM   2810 O  O   . ASP A 1 378 ? 22.545  3.811   71.169  1   18.979 ? 370  ASP A O   1 
ATOM   2811 C  CB  . ASP A 1 378 ? 20.681  1.974   72.454  1   17.565 ? 370  ASP A CB  1 
ATOM   2812 C  CG  . ASP A 1 378 ? 20.439  2.724   73.758  1   20.104 ? 370  ASP A CG  1 
ATOM   2813 O  OD1 . ASP A 1 378 ? 20.246  3.936   73.723  1   19.861 ? 370  ASP A OD1 1 
ATOM   2814 O  OD2 . ASP A 1 378 ? 20.302  2.059   74.808  1   20.156 ? 370  ASP A OD2 1 
ATOM   2815 N  N   . PRO A 1 379 ? 20.786  5.195   70.816  1   19.53  ? 371  PRO A N   1 
ATOM   2816 C  CA  . PRO A 1 379 ? 21.615  6.378   70.593  1   19.753 ? 371  PRO A CA  1 
ATOM   2817 C  C   . PRO A 1 379 ? 22.476  6.814   71.788  1   21.466 ? 371  PRO A C   1 
ATOM   2818 O  O   . PRO A 1 379 ? 23.358  7.639   71.605  1   22.058 ? 371  PRO A O   1 
ATOM   2819 C  CB  . PRO A 1 379 ? 20.656  7.5     70.22   1   23.256 ? 371  PRO A CB  1 
ATOM   2820 C  CG  . PRO A 1 379 ? 19.314  6.849   70.033  1   27.691 ? 371  PRO A CG  1 
ATOM   2821 C  CD  . PRO A 1 379 ? 19.335  5.494   70.696  1   20.222 ? 371  PRO A CD  1 
ATOM   2822 N  N   . ARG A 1 380 ? 22.234  6.209   72.965  1   20.999 ? 372  ARG A N   1 
ATOM   2823 C  CA  . ARG A 1 380 ? 23.046  6.477   74.151  1   19.753 ? 372  ARG A CA  1 
ATOM   2824 C  C   . ARG A 1 380 ? 24.369  5.718   74.088  1   23.565 ? 372  ARG A C   1 
ATOM   2825 O  O   . ARG A 1 380 ? 25.313  6.055   74.814  1   23.399 ? 372  ARG A O   1 
ATOM   2826 C  CB  . ARG A 1 380 ? 22.298  6.065   75.411  1   21.43  ? 372  ARG A CB  1 
ATOM   2827 C  CG  . ARG A 1 380 ? 21.068  6.941   75.617  1   22.026 ? 372  ARG A CG  1 
ATOM   2828 C  CD  . ARG A 1 380 ? 20.228  6.338   76.69   1   22.422 ? 372  ARG A CD  1 
ATOM   2829 N  NE  . ARG A 1 380 ? 19.709  4.983   76.446  1   21.948 ? 372  ARG A NE  1 
ATOM   2830 C  CZ  . ARG A 1 380 ? 18.867  4.304   77.182  1   21.663 ? 372  ARG A CZ  1 
ATOM   2831 N  NH1 . ARG A 1 380 ? 18.38   4.835   78.284  1   23.386 ? 372  ARG A NH1 1 
ATOM   2832 N  NH2 . ARG A 1 380 ? 18.494  3.086   76.836  1   22.983 ? 372  ARG A NH2 1 
ATOM   2833 N  N   . LYS A 1 381 ? 24.435  4.658   73.262  1   19.959 ? 373  LYS A N   1 
ATOM   2834 C  CA  . LYS A 1 381 ? 25.597  3.793   73.195  1   20.135 ? 373  LYS A CA  1 
ATOM   2835 C  C   . LYS A 1 381 ? 26.679  4.435   72.339  1   18.84  ? 373  LYS A C   1 
ATOM   2836 O  O   . LYS A 1 381 ? 26.417  5.318   71.532  1   21.429 ? 373  LYS A O   1 
ATOM   2837 C  CB  . LYS A 1 381 ? 25.262  2.375   72.719  1   21.64  ? 373  LYS A CB  1 
ATOM   2838 C  CG  . LYS A 1 381 ? 24.396  1.643   73.756  1   27.09  ? 373  LYS A CG  1 
ATOM   2839 C  CD  . LYS A 1 381 ? 24.345  0.134   73.896  1   35.904 ? 373  LYS A CD  1 
ATOM   2840 C  CE  . LYS A 1 381 ? 25.385  -0.28   74.845  1   35.231 ? 373  LYS A CE  1 
ATOM   2841 N  NZ  . LYS A 1 381 ? 25.67   -1.713  74.886  1   32.484 ? 373  LYS A NZ  1 
ATOM   2842 N  N   . ASP A 1 382 ? 27.921  3.953   72.503  1   20.258 ? 374  ASP A N   1 
ATOM   2843 C  CA  . ASP A 1 382 ? 29      4.38    71.62   1   22.783 ? 374  ASP A CA  1 
ATOM   2844 C  C   . ASP A 1 382 ? 28.775  3.767   70.223  1   19.906 ? 374  ASP A C   1 
ATOM   2845 O  O   . ASP A 1 382 ? 28.792  2.557   70.084  1   20.644 ? 374  ASP A O   1 
ATOM   2846 C  CB  . ASP A 1 382 ? 30.342  3.998   72.24   1   26.478 ? 374  ASP A CB  1 
ATOM   2847 C  CG  . ASP A 1 382 ? 31.592  4.328   71.433  1   28.389 ? 374  ASP A CG  1 
ATOM   2848 O  OD1 . ASP A 1 382 ? 31.496  4.85    70.311  1   25.918 ? 374  ASP A OD1 1 
ATOM   2849 O  OD2 . ASP A 1 382 ? 32.683  4.053   71.949  1   33.068 ? 374  ASP A OD2 1 
ATOM   2850 N  N   . ASN A 1 383 ? 28.622  4.643   69.211  1   18.664 ? 375  ASN A N   1 
ATOM   2851 C  CA  . ASN A 1 383 ? 28.353  4.168   67.841  1   18.411 ? 375  ASN A CA  1 
ATOM   2852 C  C   . ASN A 1 383 ? 29.541  3.409   67.244  1   19.856 ? 375  ASN A C   1 
ATOM   2853 O  O   . ASN A 1 383 ? 29.374  2.705   66.241  1   18.773 ? 375  ASN A O   1 
ATOM   2854 C  CB  . ASN A 1 383 ? 27.892  5.277   66.902  1   23.059 ? 375  ASN A CB  1 
ATOM   2855 C  CG  . ASN A 1 383 ? 28.954  6.32    66.678  1   25.373 ? 375  ASN A CG  1 
ATOM   2856 O  OD1 . ASN A 1 383 ? 29.33   7.019   67.618  1   28.412 ? 375  ASN A OD1 1 
ATOM   2857 N  ND2 . ASN A 1 383 ? 29.473  6.436   65.481  1   22.514 ? 375  ASN A ND2 1 
ATOM   2858 N  N   . ASN A 1 384 ? 30.747  3.492   67.84   1   20.808 ? 376  ASN A N   1 
ATOM   2859 C  CA  . ASN A 1 384 ? 31.881  2.691   67.389  1   23.471 ? 376  ASN A CA  1 
ATOM   2860 C  C   . ASN A 1 384 ? 31.792  1.23    67.827  1   20.537 ? 376  ASN A C   1 
ATOM   2861 O  O   . ASN A 1 384 ? 32.549  0.403   67.328  1   21.593 ? 376  ASN A O   1 
ATOM   2862 C  CB  . ASN A 1 384 ? 33.218  3.26    67.865  1   23.053 ? 376  ASN A CB  1 
ATOM   2863 C  CG  . ASN A 1 384 ? 33.471  4.588   67.199  1   27.257 ? 376  ASN A CG  1 
ATOM   2864 O  OD1 . ASN A 1 384 ? 33.291  4.72    65.987  1   30.29  ? 376  ASN A OD1 1 
ATOM   2865 N  ND2 . ASN A 1 384 ? 33.812  5.606   67.978  1   33.841 ? 376  ASN A ND2 1 
ATOM   2866 N  N   . GLU A 1 385 ? 30.924  0.907   68.808  1   18.948 ? 377  GLU A N   1 
ATOM   2867 C  CA  . GLU A 1 385 ? 30.738  -0.457  69.248  1   21.122 ? 377  GLU A CA  1 
ATOM   2868 C  C   . GLU A 1 385 ? 29.752  -1.154  68.301  1   18.47  ? 377  GLU A C   1 
ATOM   2869 O  O   . GLU A 1 385 ? 28.712  -0.584  67.969  1   20.069 ? 377  GLU A O   1 
ATOM   2870 C  CB  . GLU A 1 385 ? 30.184  -0.419  70.674  1   26.763 ? 377  GLU A CB  1 
ATOM   2871 C  CG  . GLU A 1 385 ? 30.004  -1.806  71.29   1   33.655 ? 377  GLU A CG  1 
ATOM   2872 C  CD  . GLU A 1 385 ? 29.894  -1.85   72.818  1   42.845 ? 377  GLU A CD  1 
ATOM   2873 O  OE1 . GLU A 1 385 ? 29.597  -0.815  73.463  1   36.56  ? 377  GLU A OE1 1 
ATOM   2874 O  OE2 . GLU A 1 385 ? 30.14   -2.954  73.354  1   43.21  ? 377  GLU A OE2 1 
ATOM   2875 N  N   . GLN A 1 386 ? 30.1    -2.364  67.902  1   16.855 ? 378  GLN A N   1 
ATOM   2876 C  CA  . GLN A 1 386 ? 29.242  -3.218  67.081  1   18.096 ? 378  GLN A CA  1 
ATOM   2877 C  C   . GLN A 1 386 ? 27.847  -3.295  67.707  1   17.58  ? 378  GLN A C   1 
ATOM   2878 O  O   . GLN A 1 386 ? 27.67   -3.545  68.92   1   18.279 ? 378  GLN A O   1 
ATOM   2879 C  CB  . GLN A 1 386 ? 29.834  -4.614  66.895  1   18.851 ? 378  GLN A CB  1 
ATOM   2880 C  CG  . GLN A 1 386 ? 29.083  -5.464  65.873  1   23.971 ? 378  GLN A CG  1 
ATOM   2881 C  CD  . GLN A 1 386 ? 29.711  -6.841  65.706  1   27.269 ? 378  GLN A CD  1 
ATOM   2882 O  OE1 . GLN A 1 386 ? 30.514  -7.076  64.801  1   34.162 ? 378  GLN A OE1 1 
ATOM   2883 N  NE2 . GLN A 1 386 ? 29.33   -7.78   66.541  1   35.97  ? 378  GLN A NE2 1 
ATOM   2884 N  N   . LEU A 1 387 ? 26.809  -3.109  66.859  1   15.843 ? 379  LEU A N   1 
ATOM   2885 C  CA  . LEU A 1 387 ? 25.418  -3.296  67.271  1   16.224 ? 379  LEU A CA  1 
ATOM   2886 C  C   . LEU A 1 387 ? 25.146  -4.716  67.76   1   15.247 ? 379  LEU A C   1 
ATOM   2887 O  O   . LEU A 1 387 ? 25.805  -5.654  67.308  1   16.448 ? 379  LEU A O   1 
ATOM   2888 C  CB  . LEU A 1 387 ? 24.453  -2.976  66.121  1   16.572 ? 379  LEU A CB  1 
ATOM   2889 C  CG  . LEU A 1 387 ? 24.4    -1.522  65.691  1   16.433 ? 379  LEU A CG  1 
ATOM   2890 C  CD1 . LEU A 1 387 ? 23.591  -1.486  64.397  1   15.632 ? 379  LEU A CD1 1 
ATOM   2891 C  CD2 . LEU A 1 387 ? 23.724  -0.684  66.747  1   15.965 ? 379  LEU A CD2 1 
ATOM   2892 N  N   . PRO A 1 388 ? 24.125  -4.906  68.623  1   17.578 ? 380  PRO A N   1 
ATOM   2893 C  CA  . PRO A 1 388 ? 23.668  -6.234  69.003  1   18.69  ? 380  PRO A CA  1 
ATOM   2894 C  C   . PRO A 1 388 ? 23.077  -6.955  67.791  1   18.909 ? 380  PRO A C   1 
ATOM   2895 O  O   . PRO A 1 388 ? 22.586  -6.337  66.825  1   18.566 ? 380  PRO A O   1 
ATOM   2896 C  CB  . PRO A 1 388 ? 22.609  -5.949  70.102  1   18.308 ? 380  PRO A CB  1 
ATOM   2897 C  CG  . PRO A 1 388 ? 22.046  -4.617  69.686  1   18.901 ? 380  PRO A CG  1 
ATOM   2898 C  CD  . PRO A 1 388 ? 23.291  -3.845  69.22   1   16.154 ? 380  PRO A CD  1 
ATOM   2899 N  N   . ASP A 1 389 ? 23.139  -8.283  67.828  1   17.872 ? 381  ASP A N   1 
ATOM   2900 C  CA  . ASP A 1 389 ? 22.601  -9.063  66.736  1   17.834 ? 381  ASP A CA  1 
ATOM   2901 C  C   . ASP A 1 389 ? 21.09   -8.823  66.649  1   18.446 ? 381  ASP A C   1 
ATOM   2902 O  O   . ASP A 1 389 ? 20.422  -8.699  67.675  1   18.252 ? 381  ASP A O   1 
ATOM   2903 C  CB  . ASP A 1 389 ? 22.771  -10.55  66.993  1   19.903 ? 381  ASP A CB  1 
ATOM   2904 C  CG  . ASP A 1 389 ? 24.19   -11.068 66.841  1   24.336 ? 381  ASP A CG  1 
ATOM   2905 O  OD1 . ASP A 1 389 ? 25.141  -10.282 66.518  1   19.86  ? 381  ASP A OD1 1 
ATOM   2906 O  OD2 . ASP A 1 389 ? 24.361  -12.297 67.099  1   26.502 ? 381  ASP A OD2 1 
ATOM   2907 N  N   . PRO A 1 390 ? 20.529  -8.722  65.419  1   17.151 ? 382  PRO A N   1 
ATOM   2908 C  CA  . PRO A 1 390 ? 19.081  -8.521  65.309  1   17.212 ? 382  PRO A CA  1 
ATOM   2909 C  C   . PRO A 1 390 ? 18.325  -9.761  65.768  1   17.947 ? 382  PRO A C   1 
ATOM   2910 O  O   . PRO A 1 390 ? 18.85   -10.889 65.682  1   17.479 ? 382  PRO A O   1 
ATOM   2911 C  CB  . PRO A 1 390 ? 18.942  -8.202  63.81   1   17.933 ? 382  PRO A CB  1 
ATOM   2912 C  CG  . PRO A 1 390 ? 20.007  -8.967  63.138  1   18.028 ? 382  PRO A CG  1 
ATOM   2913 C  CD  . PRO A 1 390 ? 21.202  -8.832  64.111  1   16.835 ? 382  PRO A CD  1 
ATOM   2914 N  N   . GLU A 1 391 ? 17.108  -9.513  66.264  1   17.69  ? 383  GLU A N   1 
ATOM   2915 C  CA  . GLU A 1 391 ? 16.23   -10.581 66.702  1   16.023 ? 383  GLU A CA  1 
ATOM   2916 C  C   . GLU A 1 391 ? 15.496  -11.146 65.488  1   17.075 ? 383  GLU A C   1 
ATOM   2917 O  O   . GLU A 1 391 ? 14.968  -10.376 64.677  1   15.945 ? 383  GLU A O   1 
ATOM   2918 C  CB  . GLU A 1 391 ? 15.254  -9.982  67.713  1   17.444 ? 383  GLU A CB  1 
ATOM   2919 C  CG  . GLU A 1 391 ? 14.322  -11.068 68.252  1   24.093 ? 383  GLU A CG  1 
ATOM   2920 C  CD  . GLU A 1 391 ? 13.272  -10.556 69.215  1   30.267 ? 383  GLU A CD  1 
ATOM   2921 O  OE1 . GLU A 1 391 ? 13.204  -9.33   69.457  1   30.25  ? 383  GLU A OE1 1 
ATOM   2922 O  OE2 . GLU A 1 391 ? 12.492  -11.398 69.703  1   33.776 ? 383  GLU A OE2 1 
ATOM   2923 N  N   . VAL A 1 392 ? 15.404  -12.476 65.378  1   16.655 ? 384  VAL A N   1 
ATOM   2924 C  CA  . VAL A 1 392 ? 14.649  -13.112 64.308  1   17.093 ? 384  VAL A CA  1 
ATOM   2925 C  C   . VAL A 1 392 ? 13.176  -13.015 64.639  1   17.866 ? 384  VAL A C   1 
ATOM   2926 O  O   . VAL A 1 392 ? 12.719  -13.521 65.678  1   20.455 ? 384  VAL A O   1 
ATOM   2927 C  CB  . VAL A 1 392 ? 15.089  -14.576 64.051  1   17.487 ? 384  VAL A CB  1 
ATOM   2928 C  CG1 . VAL A 1 392 ? 14.237  -15.247 62.975  1   18.01  ? 384  VAL A CG1 1 
ATOM   2929 C  CG2 . VAL A 1 392 ? 16.569  -14.577 63.646  1   16.407 ? 384  VAL A CG2 1 
ATOM   2930 N  N   . ILE A 1 393 ? 12.404  -12.415 63.722  1   16.923 ? 385  ILE A N   1 
ATOM   2931 C  CA  . ILE A 1 393 ? 10.965  -12.25  63.89   1   17.239 ? 385  ILE A CA  1 
ATOM   2932 C  C   . ILE A 1 393 ? 10.246  -13.326 63.093  1   17.876 ? 385  ILE A C   1 
ATOM   2933 O  O   . ILE A 1 393 ? 9.349   -13.971 63.643  1   18.739 ? 385  ILE A O   1 
ATOM   2934 C  CB  . ILE A 1 393 ? 10.542  -10.81  63.505  1   16.658 ? 385  ILE A CB  1 
ATOM   2935 C  CG1 . ILE A 1 393 ? 11.281  -9.734  64.364  1   16.708 ? 385  ILE A CG1 1 
ATOM   2936 C  CG2 . ILE A 1 393 ? 9.006   -10.615 63.554  1   16.911 ? 385  ILE A CG2 1 
ATOM   2937 C  CD1 . ILE A 1 393 ? 11.173  -9.899  65.891  1   16.845 ? 385  ILE A CD1 1 
ATOM   2938 N  N   . LEU A 1 394 ? 10.584  -13.473 61.806  1   16.129 ? 386  LEU A N   1 
ATOM   2939 C  CA  . LEU A 1 394 ? 10.102  -14.584 60.996  1   16.327 ? 386  LEU A CA  1 
ATOM   2940 C  C   . LEU A 1 394 ? 11.295  -15.355 60.462  1   19.405 ? 386  LEU A C   1 
ATOM   2941 O  O   . LEU A 1 394 ? 12.161  -14.787 59.801  1   17.1   ? 386  LEU A O   1 
ATOM   2942 C  CB  . LEU A 1 394 ? 9.173   -14.181 59.84   1   17.578 ? 386  LEU A CB  1 
ATOM   2943 C  CG  . LEU A 1 394 ? 7.947   -13.331 60.196  1   21.317 ? 386  LEU A CG  1 
ATOM   2944 C  CD1 . LEU A 1 394 ? 7.272   -13.056 58.839  1   22.473 ? 386  LEU A CD1 1 
ATOM   2945 C  CD2 . LEU A 1 394 ? 6.996   -14.079 61.162  1   23.742 ? 386  LEU A CD2 1 
ATOM   2946 N  N   . ASP A 1 395 ? 11.334  -16.668 60.73   1   17.303 ? 387  ASP A N   1 
ATOM   2947 C  CA  . ASP A 1 395 ? 12.386  -17.487 60.172  1   16.586 ? 387  ASP A CA  1 
ATOM   2948 C  C   . ASP A 1 395 ? 11.899  -18.084 58.857  1   19.574 ? 387  ASP A C   1 
ATOM   2949 O  O   . ASP A 1 395 ? 11.862  -19.29  58.666  1   18.16  ? 387  ASP A O   1 
ATOM   2950 C  CB  . ASP A 1 395 ? 12.821  -18.548 61.192  1   19.4   ? 387  ASP A CB  1 
ATOM   2951 C  CG  . ASP A 1 395 ? 14.105  -19.266 60.813  1   23.704 ? 387  ASP A CG  1 
ATOM   2952 O  OD1 . ASP A 1 395 ? 14.866  -18.783 59.958  1   21.351 ? 387  ASP A OD1 1 
ATOM   2953 O  OD2 . ASP A 1 395 ? 14.309  -20.391 61.344  1   28.364 ? 387  ASP A OD2 1 
ATOM   2954 N  N   . THR A 1 396 ? 11.558  -17.212 57.89   1   16.701 ? 388  THR A N   1 
ATOM   2955 C  CA  . THR A 1 396 ? 11.198  -17.623 56.555  1   16.365 ? 388  THR A CA  1 
ATOM   2956 C  C   . THR A 1 396 ? 11.663  -16.504 55.62   1   15.386 ? 388  THR A C   1 
ATOM   2957 O  O   . THR A 1 396 ? 11.69   -15.351 56.04   1   15.921 ? 388  THR A O   1 
ATOM   2958 C  CB  . THR A 1 396 ? 9.703   -17.971 56.398  1   19.511 ? 388  THR A CB  1 
ATOM   2959 O  OG1 . THR A 1 396 ? 9.572   -18.765 55.199  1   20.499 ? 388  THR A OG1 1 
ATOM   2960 C  CG2 . THR A 1 396 ? 8.78    -16.771 56.233  1   19.561 ? 388  THR A CG2 1 
ATOM   2961 N  N   . PRO A 1 397 ? 12.045  -16.819 54.373  1   16.38  ? 389  PRO A N   1 
ATOM   2962 C  CA  . PRO A 1 397 ? 12.378  -15.757 53.417  1   14.657 ? 389  PRO A CA  1 
ATOM   2963 C  C   . PRO A 1 397 ? 11.197  -14.796 53.298  1   16.202 ? 389  PRO A C   1 
ATOM   2964 O  O   . PRO A 1 397 ? 10.039  -15.219 53.135  1   15.928 ? 389  PRO A O   1 
ATOM   2965 C  CB  . PRO A 1 397 ? 12.682  -16.48  52.119  1   18.183 ? 389  PRO A CB  1 
ATOM   2966 C  CG  . PRO A 1 397 ? 13.145  -17.892 52.585  1   19.951 ? 389  PRO A CG  1 
ATOM   2967 C  CD  . PRO A 1 397 ? 12.269  -18.175 53.792  1   18.198 ? 389  PRO A CD  1 
ATOM   2968 N  N   . SER A 1 398 ? 11.526  -13.501 53.451  1   13.887 ? 390  SER A N   1 
ATOM   2969 C  CA  . SER A 1 398 ? 10.568  -12.416 53.649  1   13.508 ? 390  SER A CA  1 
ATOM   2970 C  C   . SER A 1 398 ? 11.075  -11.221 52.837  1   13.794 ? 390  SER A C   1 
ATOM   2971 O  O   . SER A 1 398 ? 12.293  -10.928 52.83   1   15.304 ? 390  SER A O   1 
ATOM   2972 C  CB  . SER A 1 398 ? 10.556  -12.024 55.113  1   15.087 ? 390  SER A CB  1 
ATOM   2973 O  OG  . SER A 1 398 ? 10.021  -13.093 55.9    1   15.026 ? 390  SER A OG  1 
ATOM   2974 N  N   . GLU A 1 399 ? 10.163  -10.52  52.157  1   12.577 ? 391  GLU A N   1 
ATOM   2975 C  CA  . GLU A 1 399 ? 10.637  -9.346  51.414  1   12.701 ? 391  GLU A CA  1 
ATOM   2976 C  C   . GLU A 1 399 ? 9.414   -8.451  51.206  1   13.506 ? 391  GLU A C   1 
ATOM   2977 O  O   . GLU A 1 399 ? 8.329   -8.72   51.663  1   12.594 ? 391  GLU A O   1 
ATOM   2978 C  CB  . GLU A 1 399 ? 11.411  -9.674  50.105  1   12.346 ? 391  GLU A CB  1 
ATOM   2979 C  CG  . GLU A 1 399 ? 12.822  -9.054  50.126  1   17.244 ? 391  GLU A CG  1 
ATOM   2980 C  CD  . GLU A 1 399 ? 12.726  -7.568  50.361  1   14.507 ? 391  GLU A CD  1 
ATOM   2981 O  OE1 . GLU A 1 399 ? 12.203  -6.935  49.412  1   16.317 ? 391  GLU A OE1 1 
ATOM   2982 O  OE2 . GLU A 1 399 ? 13.06   -7.042  51.385  1   16.924 ? 391  GLU A OE2 1 
ATOM   2983 N  N   . PHE A 1 400 ? 9.636   -7.293  50.564  1   12.216 ? 392  PHE A N   1 
ATOM   2984 C  CA  . PHE A 1 400 ? 8.593   -6.34   50.225  1   11.447 ? 392  PHE A CA  1 
ATOM   2985 C  C   . PHE A 1 400 ? 7.624   -6.13   51.377  1   11.831 ? 392  PHE A C   1 
ATOM   2986 O  O   . PHE A 1 400 ? 6.412   -6.176  51.164  1   12.534 ? 392  PHE A O   1 
ATOM   2987 C  CB  . PHE A 1 400 ? 7.877   -6.727  48.928  1   12.337 ? 392  PHE A CB  1 
ATOM   2988 C  CG  . PHE A 1 400 ? 8.79    -6.67   47.718  1   14.097 ? 392  PHE A CG  1 
ATOM   2989 C  CD1 . PHE A 1 400 ? 9.257   -5.447  47.239  1   14.999 ? 392  PHE A CD1 1 
ATOM   2990 C  CD2 . PHE A 1 400 ? 9.115   -7.845  47.012  1   14.48  ? 392  PHE A CD2 1 
ATOM   2991 C  CE1 . PHE A 1 400 ? 10.082  -5.385  46.101  1   14.893 ? 392  PHE A CE1 1 
ATOM   2992 C  CE2 . PHE A 1 400 ? 9.945   -7.764  45.888  1   15.286 ? 392  PHE A CE2 1 
ATOM   2993 C  CZ  . PHE A 1 400 ? 10.396  -6.541  45.412  1   15.642 ? 392  PHE A CZ  1 
ATOM   2994 N  N   . PRO A 1 401 ? 8.093   -5.745  52.587  1   11.989 ? 393  PRO A N   1 
ATOM   2995 C  CA  . PRO A 1 401 ? 7.175   -5.383  53.657  1   11.709 ? 393  PRO A CA  1 
ATOM   2996 C  C   . PRO A 1 401 ? 6.588   -3.976  53.479  1   12.231 ? 393  PRO A C   1 
ATOM   2997 O  O   . PRO A 1 401 ? 7.266   -3.072  52.994  1   12.449 ? 393  PRO A O   1 
ATOM   2998 C  CB  . PRO A 1 401 ? 8.116   -5.417  54.908  1   12.288 ? 393  PRO A CB  1 
ATOM   2999 C  CG  . PRO A 1 401 ? 9.467   -4.926  54.33   1   12.513 ? 393  PRO A CG  1 
ATOM   3000 C  CD  . PRO A 1 401 ? 9.529   -5.561  52.943  1   12.345 ? 393  PRO A CD  1 
ATOM   3001 N  N   . GLN A 1 402 ? 5.33    -3.823  53.904  1   11.204 ? 394  GLN A N   1 
ATOM   3002 C  CA  . GLN A 1 402 ? 4.711   -2.509  54.037  1   12.637 ? 394  GLN A CA  1 
ATOM   3003 C  C   . GLN A 1 402 ? 3.987   -2.483  55.377  1   12.261 ? 394  GLN A C   1 
ATOM   3004 O  O   . GLN A 1 402 ? 3.868   -3.509  56.059  1   12.48  ? 394  GLN A O   1 
ATOM   3005 C  CB  . GLN A 1 402 ? 3.725   -2.166  52.917  1   12.232 ? 394  GLN A CB  1 
ATOM   3006 C  CG  . GLN A 1 402 ? 4.448   -1.799  51.606  1   12.745 ? 394  GLN A CG  1 
ATOM   3007 C  CD  . GLN A 1 402 ? 3.598   -1.027  50.627  1   12.609 ? 394  GLN A CD  1 
ATOM   3008 O  OE1 . GLN A 1 402 ? 2.505   -0.544  50.955  1   13.692 ? 394  GLN A OE1 1 
ATOM   3009 N  NE2 . GLN A 1 402 ? 4.153   -0.837  49.43   1   12.345 ? 394  GLN A NE2 1 
ATOM   3010 N  N   . ILE A 1 403 ? 3.528   -1.29   55.776  1   11.667 ? 395  ILE A N   1 
ATOM   3011 C  CA  . ILE A 1 403 ? 2.853   -1.129  57.063  1   12.285 ? 395  ILE A CA  1 
ATOM   3012 C  C   . ILE A 1 403 ? 1.529   -0.388  56.85   1   11.938 ? 395  ILE A C   1 
ATOM   3013 O  O   . ILE A 1 403 ? 1.096   -0.143  55.729  1   12.334 ? 395  ILE A O   1 
ATOM   3014 C  CB  . ILE A 1 403 ? 3.783   -0.401  58.067  1   12.571 ? 395  ILE A CB  1 
ATOM   3015 C  CG1 . ILE A 1 403 ? 4.017   1.084   57.705  1   12.659 ? 395  ILE A CG1 1 
ATOM   3016 C  CG2 . ILE A 1 403 ? 5.117   -1.155  58.247  1   12.395 ? 395  ILE A CG2 1 
ATOM   3017 C  CD1 . ILE A 1 403 ? 4.278   1.927   58.961  1   13.312 ? 395  ILE A CD1 1 
ATOM   3018 N  N   . ASP A 1 404 ? 0.885   -0.035  57.971  1   13.338 ? 396  ASP A N   1 
ATOM   3019 C  CA  . ASP A 1 404 ? -0.247  0.876   57.99   1   13.617 ? 396  ASP A CA  1 
ATOM   3020 C  C   . ASP A 1 404 ? 0.313   2.291   58.108  1   13.393 ? 396  ASP A C   1 
ATOM   3021 O  O   . ASP A 1 404 ? 0.794   2.685   59.173  1   14.124 ? 396  ASP A O   1 
ATOM   3022 C  CB  . ASP A 1 404 ? -1.198  0.476   59.127  1   12.204 ? 396  ASP A CB  1 
ATOM   3023 C  CG  . ASP A 1 404 ? -2.429  1.382   59.311  1   14.05  ? 396  ASP A CG  1 
ATOM   3024 O  OD1 . ASP A 1 404 ? -2.522  2.457   58.697  1   14.65  ? 396  ASP A OD1 1 
ATOM   3025 O  OD2 . ASP A 1 404 ? -3.35   0.938   60.034  1   15.504 ? 396  ASP A OD2 1 
ATOM   3026 N  N   . ASN A 1 405 ? 0.266   3.044   57.002  1   13.877 ? 397  ASN A N   1 
ATOM   3027 C  CA  . ASN A 1 405 ? 0.996   4.31    56.883  1   14.659 ? 397  ASN A CA  1 
ATOM   3028 C  C   . ASN A 1 405 ? 0.399   5.404   57.764  1   13.991 ? 397  ASN A C   1 
ATOM   3029 O  O   . ASN A 1 405 ? 1.03    6.444   57.962  1   15.002 ? 397  ASN A O   1 
ATOM   3030 C  CB  . ASN A 1 405 ? 1.065   4.773   55.431  1   15.022 ? 397  ASN A CB  1 
ATOM   3031 C  CG  . ASN A 1 405 ? 2.065   3.964   54.65   1   15.617 ? 397  ASN A CG  1 
ATOM   3032 O  OD1 . ASN A 1 405 ? 2.957   3.376   55.242  1   14.833 ? 397  ASN A OD1 1 
ATOM   3033 N  ND2 . ASN A 1 405 ? 1.967   3.98    53.334  1   17.1   ? 397  ASN A ND2 1 
ATOM   3034 N  N   . ARG A 1 406 ? -0.762  5.124   58.368  1   13.606 ? 398  ARG A N   1 
ATOM   3035 C  CA  . ARG A 1 406 ? -1.215  6.044   59.42   1   13.589 ? 398  ARG A CA  1 
ATOM   3036 C  C   . ARG A 1 406 ? -0.274  6.034   60.616  1   15.535 ? 398  ARG A C   1 
ATOM   3037 O  O   . ARG A 1 406 ? -0.377  6.928   61.478  1   16.782 ? 398  ARG A O   1 
ATOM   3038 C  CB  . ARG A 1 406 ? -2.633  5.62    59.844  1   14.75  ? 398  ARG A CB  1 
ATOM   3039 C  CG  . ARG A 1 406 ? -3.645  5.82    58.715  1   14.59  ? 398  ARG A CG  1 
ATOM   3040 C  CD  . ARG A 1 406 ? -5.014  5.335   59.132  1   15.095 ? 398  ARG A CD  1 
ATOM   3041 N  NE  . ARG A 1 406 ? -5.034  3.903   59.445  1   16.113 ? 398  ARG A NE  1 
ATOM   3042 C  CZ  . ARG A 1 406 ? -5.983  3.282   60.126  1   16.464 ? 398  ARG A CZ  1 
ATOM   3043 N  NH1 . ARG A 1 406 ? -7.104  3.971   60.466  1   17.179 ? 398  ARG A NH1 1 
ATOM   3044 N  NH2 . ARG A 1 406 ? -5.834  2.033   60.451  1   17.054 ? 398  ARG A NH2 1 
ATOM   3045 N  N   . PHE A 1 407 ? 0.635   5.045   60.672  1   13.983 ? 399  PHE A N   1 
ATOM   3046 C  CA  . PHE A 1 407 ? 1.616   4.908   61.743  1   13.398 ? 399  PHE A CA  1 
ATOM   3047 C  C   . PHE A 1 407 ? 3.047   5.077   61.188  1   13.083 ? 399  PHE A C   1 
ATOM   3048 O  O   . PHE A 1 407 ? 4.016   4.765   61.914  1   14.511 ? 399  PHE A O   1 
ATOM   3049 C  CB  . PHE A 1 407 ? 1.434   3.559   62.464  1   14.408 ? 399  PHE A CB  1 
ATOM   3050 C  CG  . PHE A 1 407 ? 0.054   3.5     63.102  1   15.163 ? 399  PHE A CG  1 
ATOM   3051 C  CD1 . PHE A 1 407 ? -1.072  3.154   62.347  1   17.104 ? 399  PHE A CD1 1 
ATOM   3052 C  CD2 . PHE A 1 407 ? -0.088  3.784   64.468  1   17.515 ? 399  PHE A CD2 1 
ATOM   3053 C  CE1 . PHE A 1 407 ? -2.357  3.175   62.9    1   16.899 ? 399  PHE A CE1 1 
ATOM   3054 C  CE2 . PHE A 1 407 ? -1.384  3.781   65.041  1   17.592 ? 399  PHE A CE2 1 
ATOM   3055 C  CZ  . PHE A 1 407 ? -2.51   3.472   64.263  1   16.763 ? 399  PHE A CZ  1 
ATOM   3056 N  N   . MET A 1 408 ? 3.18    5.713   60.011  1   13.008 ? 400  MET A N   1 
ATOM   3057 C  CA  . MET A 1 408 ? 4.5     5.917   59.447  1   12.917 ? 400  MET A CA  1 
ATOM   3058 C  C   . MET A 1 408 ? 5.215   7.007   60.254  1   13.811 ? 400  MET A C   1 
ATOM   3059 O  O   . MET A 1 408 ? 4.72    8.117   60.411  1   14.603 ? 400  MET A O   1 
ATOM   3060 C  CB  . MET A 1 408 ? 4.374   6.288   57.958  1   12.275 ? 400  MET A CB  1 
ATOM   3061 C  CG  . MET A 1 408 ? 5.74    6.585   57.327  1   14.397 ? 400  MET A CG  1 
ATOM   3062 S  SD  . MET A 1 408 ? 7.014   5.308   57.521  1   14.292 ? 400  MET A SD  1 
ATOM   3063 C  CE  . MET A 1 408 ? 6.419   4.108   56.33   1   15.423 ? 400  MET A CE  1 
ATOM   3064 N  N   . GLY A 1 409 ? 6.438   6.703   60.679  1   13.55  ? 401  GLY A N   1 
ATOM   3065 C  CA  . GLY A 1 409 ? 7.271   7.619   61.449  1   15.423 ? 401  GLY A CA  1 
ATOM   3066 C  C   . GLY A 1 409 ? 6.924   7.662   62.946  1   16.308 ? 401  GLY A C   1 
ATOM   3067 O  O   . GLY A 1 409 ? 7.502   8.492   63.65   1   16.807 ? 401  GLY A O   1 
ATOM   3068 N  N   . VAL A 1 410 ? 6.03    6.797   63.416  1   14.942 ? 402  VAL A N   1 
ATOM   3069 C  CA  . VAL A 1 410 ? 5.72    6.65    64.844  1   14.861 ? 402  VAL A CA  1 
ATOM   3070 C  C   . VAL A 1 410 ? 5.705   5.169   65.184  1   15.131 ? 402  VAL A C   1 
ATOM   3071 O  O   . VAL A 1 410 ? 5.891   4.325   64.293  1   15.126 ? 402  VAL A O   1 
ATOM   3072 C  CB  . VAL A 1 410 ? 4.406   7.355   65.233  1   16.177 ? 402  VAL A CB  1 
ATOM   3073 C  CG1 . VAL A 1 410 ? 4.486   8.855   64.974  1   15.678 ? 402  VAL A CG1 1 
ATOM   3074 C  CG2 . VAL A 1 410 ? 3.181   6.749   64.533  1   14.704 ? 402  VAL A CG2 1 
ATOM   3075 N  N   . GLU A 1 411 ? 5.428   4.825   66.47   1   14.717 ? 403  GLU A N   1 
ATOM   3076 C  CA  . GLU A 1 411 ? 5.316   3.419   66.803  1   15.055 ? 403  GLU A CA  1 
ATOM   3077 C  C   . GLU A 1 411 ? 4.238   2.751   65.932  1   14.746 ? 403  GLU A C   1 
ATOM   3078 O  O   . GLU A 1 411 ? 3.111   3.243   65.803  1   16.935 ? 403  GLU A O   1 
ATOM   3079 C  CB  . GLU A 1 411 ? 5.075   3.24    68.302  1   16.974 ? 403  GLU A CB  1 
ATOM   3080 C  CG  . GLU A 1 411 ? 4.946   1.764   68.689  1   17.508 ? 403  GLU A CG  1 
ATOM   3081 C  CD  . GLU A 1 411 ? 4.866   1.512   70.188  1   20.304 ? 403  GLU A CD  1 
ATOM   3082 O  OE1 . GLU A 1 411 ? 4.951   2.485   70.96   1   25.525 ? 403  GLU A OE1 1 
ATOM   3083 O  OE2 . GLU A 1 411 ? 4.695   0.341   70.57   1   23.625 ? 403  GLU A OE2 1 
ATOM   3084 N  N   . TYR A 1 412 ? 4.621   1.611   65.353  1   13.5   ? 404  TYR A N   1 
ATOM   3085 C  CA  . TYR A 1 412 ? 3.748   0.818   64.513  1   13.552 ? 404  TYR A CA  1 
ATOM   3086 C  C   . TYR A 1 412 ? 3.815   -0.623  64.981  1   14.65  ? 404  TYR A C   1 
ATOM   3087 O  O   . TYR A 1 412 ? 4.788   -1.027  65.624  1   15.363 ? 404  TYR A O   1 
ATOM   3088 C  CB  . TYR A 1 412 ? 4.127   1.005   63.028  1   13.465 ? 404  TYR A CB  1 
ATOM   3089 C  CG  . TYR A 1 412 ? 5.309   0.119   62.626  1   14.339 ? 404  TYR A CG  1 
ATOM   3090 C  CD1 . TYR A 1 412 ? 6.614   0.47    62.923  1   14.043 ? 404  TYR A CD1 1 
ATOM   3091 C  CD2 . TYR A 1 412 ? 5.097   -1.085  61.952  1   14.34  ? 404  TYR A CD2 1 
ATOM   3092 C  CE1 . TYR A 1 412 ? 7.678   -0.352  62.611  1   14.264 ? 404  TYR A CE1 1 
ATOM   3093 C  CE2 . TYR A 1 412 ? 6.158   -1.932  61.617  1   14.68  ? 404  TYR A CE2 1 
ATOM   3094 C  CZ  . TYR A 1 412 ? 7.456   -1.546  61.937  1   13.31  ? 404  TYR A CZ  1 
ATOM   3095 O  OH  . TYR A 1 412 ? 8.508   -2.362  61.652  1   14.479 ? 404  TYR A OH  1 
ATOM   3096 N  N   . SER A 1 413 ? 2.783   -1.399  64.606  1   15.676 ? 405  SER A N   1 
ATOM   3097 C  CA  . SER A 1 413 ? 2.665   -2.79   65.002  1   15.739 ? 405  SER A CA  1 
ATOM   3098 C  C   . SER A 1 413 ? 2.441   -3.741  63.815  1   14.451 ? 405  SER A C   1 
ATOM   3099 O  O   . SER A 1 413 ? 3.066   -4.802  63.777  1   14.989 ? 405  SER A O   1 
ATOM   3100 C  CB  . SER A 1 413 ? 1.557   -2.912  66.062  1   15.92  ? 405  SER A CB  1 
ATOM   3101 O  OG  . SER A 1 413 ? 1.36    -4.277  66.417  1   16.913 ? 405  SER A OG  1 
ATOM   3102 N  N   . SER A 1 414 ? 1.519   -3.395  62.893  1   13.679 ? 406  SER A N   1 
ATOM   3103 C  CA  . SER A 1 414 ? 1.247   -4.269  61.744  1   14.328 ? 406  SER A CA  1 
ATOM   3104 C  C   . SER A 1 414 ? 2.368   -4.16   60.718  1   13.029 ? 406  SER A C   1 
ATOM   3105 O  O   . SER A 1 414 ? 2.769   -3.041  60.346  1   15.032 ? 406  SER A O   1 
ATOM   3106 C  CB  . SER A 1 414 ? -0.045  -3.897  61.09   1   15.126 ? 406  SER A CB  1 
ATOM   3107 O  OG  . SER A 1 414 ? -1.179  -4.474  61.752  1   15.024 ? 406  SER A OG  1 
ATOM   3108 N  N   . ALA A 1 415 ? 2.764   -5.305  60.191  1   13.105 ? 407  ALA A N   1 
ATOM   3109 C  CA  . ALA A 1 415 ? 3.571   -5.382  58.966  1   13.209 ? 407  ALA A CA  1 
ATOM   3110 C  C   . ALA A 1 415 ? 2.938   -6.393  58.026  1   13.743 ? 407  ALA A C   1 
ATOM   3111 O  O   . ALA A 1 415 ? 2.523   -7.464  58.454  1   14.377 ? 407  ALA A O   1 
ATOM   3112 C  CB  . ALA A 1 415 ? 5.02    -5.732  59.252  1   13.279 ? 407  ALA A CB  1 
ATOM   3113 N  N   . PHE A 1 416 ? 2.834   -6.006  56.754  1   12.73  ? 408  PHE A N   1 
ATOM   3114 C  CA  . PHE A 1 416 ? 2.32    -6.859  55.687  1   11.992 ? 408  PHE A CA  1 
ATOM   3115 C  C   . PHE A 1 416 ? 3.517   -7.267  54.852  1   12.681 ? 408  PHE A C   1 
ATOM   3116 O  O   . PHE A 1 416 ? 4.189   -6.398  54.315  1   13.293 ? 408  PHE A O   1 
ATOM   3117 C  CB  . PHE A 1 416 ? 1.273   -6.113  54.853  1   13.077 ? 408  PHE A CB  1 
ATOM   3118 C  CG  . PHE A 1 416 ? 0.156   -5.547  55.715  1   12.716 ? 408  PHE A CG  1 
ATOM   3119 C  CD1 . PHE A 1 416 ? -0.833  -6.395  56.214  1   12.869 ? 408  PHE A CD1 1 
ATOM   3120 C  CD2 . PHE A 1 416 ? 0.156   -4.19   56.099  1   14.879 ? 408  PHE A CD2 1 
ATOM   3121 C  CE1 . PHE A 1 416 ? -1.866  -5.875  57.035  1   13.873 ? 408  PHE A CE1 1 
ATOM   3122 C  CE2 . PHE A 1 416 ? -0.832  -3.694  56.926  1   15.58  ? 408  PHE A CE2 1 
ATOM   3123 C  CZ  . PHE A 1 416 ? -1.834  -4.553  57.398  1   15.967 ? 408  PHE A CZ  1 
ATOM   3124 N  N   . ILE A 1 417 ? 3.828   -8.571  54.767  1   12.971 ? 409  ILE A N   1 
ATOM   3125 C  CA  . ILE A 1 417 ? 5.139   -9.021  54.291  1   12.278 ? 409  ILE A CA  1 
ATOM   3126 C  C   . ILE A 1 417 ? 4.931   -10.057 53.193  1   13.017 ? 409  ILE A C   1 
ATOM   3127 O  O   . ILE A 1 417 ? 4.068   -10.947 53.318  1   13.817 ? 409  ILE A O   1 
ATOM   3128 C  CB  . ILE A 1 417 ? 5.912   -9.648  55.469  1   12.52  ? 409  ILE A CB  1 
ATOM   3129 C  CG1 . ILE A 1 417 ? 5.978   -8.694  56.664  1   13.925 ? 409  ILE A CG1 1 
ATOM   3130 C  CG2 . ILE A 1 417 ? 7.315   -10.054 55.027  1   13.65  ? 409  ILE A CG2 1 
ATOM   3131 C  CD1 . ILE A 1 417 ? 6.535   -9.347  57.928  1   14.374 ? 409  ILE A CD1 1 
ATOM   3132 N  N   . ASN A 1 418 ? 5.709   -9.951  52.104  1   12.07  ? 410  ASN A N   1 
ATOM   3133 C  CA  . ASN A 1 418 ? 5.703   -10.955 51.046  1   12.425 ? 410  ASN A CA  1 
ATOM   3134 C  C   . ASN A 1 418 ? 6.609   -12.097 51.513  1   14.6   ? 410  ASN A C   1 
ATOM   3135 O  O   . ASN A 1 418 ? 7.74    -11.828 51.953  1   14.003 ? 410  ASN A O   1 
ATOM   3136 C  CB  . ASN A 1 418 ? 6.216   -10.283 49.776  1   13.716 ? 410  ASN A CB  1 
ATOM   3137 C  CG  . ASN A 1 418 ? 5.808   -10.863 48.437  1   13.11  ? 410  ASN A CG  1 
ATOM   3138 O  OD1 . ASN A 1 418 ? 4.996   -11.823 48.298  1   16.642 ? 410  ASN A OD1 1 
ATOM   3139 N  ND2 . ASN A 1 418 ? 6.338   -10.195 47.439  1   11.863 ? 410  ASN A ND2 1 
ATOM   3140 N  N   . VAL A 1 419 ? 6.075   -13.33  51.514  1   13.811 ? 411  VAL A N   1 
ATOM   3141 C  CA  . VAL A 1 419 ? 6.842   -14.43  52.114  1   13.299 ? 411  VAL A CA  1 
ATOM   3142 C  C   . VAL A 1 419 ? 6.933   -15.643 51.196  1   13.43  ? 411  VAL A C   1 
ATOM   3143 O  O   . VAL A 1 419 ? 6.06    -15.873 50.361  1   14.769 ? 411  VAL A O   1 
ATOM   3144 C  CB  . VAL A 1 419 ? 6.245   -14.847 53.463  1   13.965 ? 411  VAL A CB  1 
ATOM   3145 C  CG1 . VAL A 1 419 ? 6.405   -13.764 54.537  1   15.33  ? 411  VAL A CG1 1 
ATOM   3146 C  CG2 . VAL A 1 419 ? 4.779   -15.273 53.341  1   14.758 ? 411  VAL A CG2 1 
ATOM   3147 N  N   . PHE A 1 420 ? 7.968   -16.45  51.449  1   15.26  ? 412  PHE A N   1 
ATOM   3148 C  CA  . PHE A 1 420 ? 7.96    -17.86  51.061  1   16.387 ? 412  PHE A CA  1 
ATOM   3149 C  C   . PHE A 1 420 ? 7.177   -18.588 52.148  1   15.545 ? 412  PHE A C   1 
ATOM   3150 O  O   . PHE A 1 420 ? 7.537   -18.513 53.322  1   18.727 ? 412  PHE A O   1 
ATOM   3151 C  CB  . PHE A 1 420 ? 9.395   -18.429 51.118  1   18.127 ? 412  PHE A CB  1 
ATOM   3152 C  CG  . PHE A 1 420 ? 10.378  -18.083 50.01   1   19.01  ? 412  PHE A CG  1 
ATOM   3153 C  CD1 . PHE A 1 420 ? 10.461  -16.782 49.472  1   18.694 ? 412  PHE A CD1 1 
ATOM   3154 C  CD2 . PHE A 1 420 ? 11.286  -19.042 49.517  1   20.674 ? 412  PHE A CD2 1 
ATOM   3155 C  CE1 . PHE A 1 420 ? 11.394  -16.453 48.48   1   17.312 ? 412  PHE A CE1 1 
ATOM   3156 C  CE2 . PHE A 1 420 ? 12.21   -18.729 48.512  1   21.148 ? 412  PHE A CE2 1 
ATOM   3157 C  CZ  . PHE A 1 420 ? 12.271  -17.427 47.987  1   18.859 ? 412  PHE A CZ  1 
ATOM   3158 N  N   . VAL A 1 421 ? 6.067   -19.223 51.777  1   17.286 ? 413  VAL A N   1 
ATOM   3159 C  CA  . VAL A 1 421 ? 5.195   -19.785 52.805  1   17.724 ? 413  VAL A CA  1 
ATOM   3160 C  C   . VAL A 1 421 ? 5.882   -21.008 53.429  1   20.305 ? 413  VAL A C   1 
ATOM   3161 O  O   . VAL A 1 421 ? 6.299   -21.893 52.683  1   21.334 ? 413  VAL A O   1 
ATOM   3162 C  CB  . VAL A 1 421 ? 3.854   -20.174 52.149  1   19.876 ? 413  VAL A CB  1 
ATOM   3163 C  CG1 . VAL A 1 421 ? 2.985   -21.01  53.103  1   21.379 ? 413  VAL A CG1 1 
ATOM   3164 C  CG2 . VAL A 1 421 ? 3.097   -18.904 51.772  1   19.575 ? 413  VAL A CG2 1 
ATOM   3165 N  N   . PRO A 1 422 ? 6.013   -21.073 54.781  1   21.008 ? 414  PRO A N   1 
ATOM   3166 C  CA  . PRO A 1 422 ? 6.697   -22.213 55.424  1   23.83  ? 414  PRO A CA  1 
ATOM   3167 C  C   . PRO A 1 422 ? 6.094   -23.552 54.973  1   27.126 ? 414  PRO A C   1 
ATOM   3168 O  O   . PRO A 1 422 ? 4.87    -23.686 54.896  1   23.594 ? 414  PRO A O   1 
ATOM   3169 C  CB  . PRO A 1 422 ? 6.42    -21.925 56.919  1   23.451 ? 414  PRO A CB  1 
ATOM   3170 C  CG  . PRO A 1 422 ? 6.415   -20.419 57.025  1   21.444 ? 414  PRO A CG  1 
ATOM   3171 C  CD  . PRO A 1 422 ? 5.572   -20.062 55.772  1   21.459 ? 414  PRO A CD  1 
ATOM   3172 N  N   . ASP A 1 423 ? 6.967   -24.475 54.552  1   27.27  ? 415  ASP A N   1 
ATOM   3173 C  CA  . ASP A 1 423 ? 6.635   -25.86  54.181  1   31.296 ? 415  ASP A CA  1 
ATOM   3174 C  C   . ASP A 1 423 ? 5.955   -25.965 52.816  1   31.783 ? 415  ASP A C   1 
ATOM   3175 O  O   . ASP A 1 423 ? 5.608   -27.063 52.385  1   32.71  ? 415  ASP A O   1 
ATOM   3176 C  CB  . ASP A 1 423 ? 5.878   -26.631 55.274  1   32.764 ? 415  ASP A CB  1 
ATOM   3177 C  CG  . ASP A 1 423 ? 6.518   -26.58  56.654  1   36.244 ? 415  ASP A CG  1 
ATOM   3178 O  OD1 . ASP A 1 423 ? 7.738   -26.835 56.728  1   32.717 ? 415  ASP A OD1 1 
ATOM   3179 O  OD2 . ASP A 1 423 ? 5.801   -26.233 57.618  1   41.586 ? 415  ASP A OD2 1 
ATOM   3180 N  N   . ARG A 1 424 ? 5.836   -24.843 52.093  1   26.841 ? 416  ARG A N   1 
ATOM   3181 C  CA  . ARG A 1 424 ? 5.134   -24.805 50.819  1   27.869 ? 416  ARG A CA  1 
ATOM   3182 C  C   . ARG A 1 424 ? 5.899   -23.929 49.828  1   32.586 ? 416  ARG A C   1 
ATOM   3183 O  O   . ARG A 1 424 ? 5.309   -23.348 48.912  1   33.405 ? 416  ARG A O   1 
ATOM   3184 C  CB  . ARG A 1 424 ? 3.735   -24.178 50.946  1   30.07  ? 416  ARG A CB  1 
ATOM   3185 C  CG  . ARG A 1 424 ? 2.819   -24.457 52.128  1   37.501 ? 416  ARG A CG  1 
ATOM   3186 C  CD  . ARG A 1 424 ? 1.515   -25.18  51.878  1   37.123 ? 416  ARG A CD  1 
ATOM   3187 N  NE  . ARG A 1 424 ? 0.913   -25.352 50.549  1   36.625 ? 416  ARG A NE  1 
ATOM   3188 C  CZ  . ARG A 1 424 ? -0.385  -25.25  50.198  1   32.086 ? 416  ARG A CZ  1 
ATOM   3189 N  NH1 . ARG A 1 424 ? -1.226  -24.519 50.912  1   33.354 ? 416  ARG A NH1 1 
ATOM   3190 N  NH2 . ARG A 1 424 ? -0.817  -25.87  49.101  1   32.574 ? 416  ARG A NH2 1 
ATOM   3191 N  N   . SER A 1 425 ? 7.218   -23.856 50.005  1   32.472 ? 417  SER A N   1 
ATOM   3192 C  CA  . SER A 1 425 ? 8.043   -22.968 49.203  1   30.353 ? 417  SER A CA  1 
ATOM   3193 C  C   . SER A 1 425 ? 9.409   -23.605 48.979  1   33.604 ? 417  SER A C   1 
ATOM   3194 O  O   . SER A 1 425 ? 9.778   -24.563 49.668  1   32.066 ? 417  SER A O   1 
ATOM   3195 C  CB  . SER A 1 425 ? 8.122   -21.574 49.807  1   26.522 ? 417  SER A CB  1 
ATOM   3196 O  OG  . SER A 1 425 ? 8.562   -21.633 51.158  1   25.907 ? 417  SER A OG  1 
ATOM   3197 N  N   . ASP A 1 426 ? 10.128  -23.049 47.997  1   33.993 ? 418  ASP A N   1 
ATOM   3198 C  CA  . ASP A 1 426 ? 11.428  -23.558 47.597  1   38.44  ? 418  ASP A CA  1 
ATOM   3199 C  C   . ASP A 1 426 ? 12.51   -22.628 48.147  1   35.34  ? 418  ASP A C   1 
ATOM   3200 O  O   . ASP A 1 426 ? 12.794  -21.588 47.537  1   28.769 ? 418  ASP A O   1 
ATOM   3201 C  CB  . ASP A 1 426 ? 11.465  -23.792 46.092  1   41.304 ? 418  ASP A CB  1 
ATOM   3202 C  CG  . ASP A 1 426 ? 12.774  -24.322 45.511  1   41.875 ? 418  ASP A CG  1 
ATOM   3203 O  OD1 . ASP A 1 426 ? 13.725  -24.649 46.284  1   40.065 ? 418  ASP A OD1 1 
ATOM   3204 O  OD2 . ASP A 1 426 ? 12.829  -24.399 44.277  1   48.746 ? 418  ASP A OD2 1 
ATOM   3205 N  N   . GLY A 1 427 ? 13.136  -23.058 49.261  1   32.238 ? 419  GLY A N   1 
ATOM   3206 C  CA  . GLY A 1 427 ? 14.139  -22.286 49.977  1   35.213 ? 419  GLY A CA  1 
ATOM   3207 C  C   . GLY A 1 427 ? 15.412  -22.048 49.156  1   33.451 ? 419  GLY A C   1 
ATOM   3208 O  O   . GLY A 1 427 ? 16.214  -21.194 49.532  1   36.595 ? 419  GLY A O   1 
ATOM   3209 N  N   . ASN A 1 428 ? 15.569  -22.789 48.039  1   29.338 ? 420  ASN A N   1 
ATOM   3210 C  CA  . ASN A 1 428 ? 16.758  -22.621 47.221  1   32.904 ? 420  ASN A CA  1 
ATOM   3211 C  C   . ASN A 1 428 ? 16.581  -21.495 46.207  1   25.902 ? 420  ASN A C   1 
ATOM   3212 O  O   . ASN A 1 428 ? 17.554  -21.158 45.543  1   25.849 ? 420  ASN A O   1 
ATOM   3213 C  CB  . ASN A 1 428 ? 17.337  -23.931 46.69   1   42.592 ? 420  ASN A CB  1 
ATOM   3214 C  CG  . ASN A 1 428 ? 18.697  -24.192 47.315  1   59.079 ? 420  ASN A CG  1 
ATOM   3215 O  OD1 . ASN A 1 428 ? 19.69   -23.508 47.008  1   54.411 ? 420  ASN A OD1 1 
ATOM   3216 N  ND2 . ASN A 1 428 ? 18.759  -25.158 48.222  1   66.341 ? 420  ASN A ND2 1 
ATOM   3217 N  N   . LYS A 1 429 ? 15.355  -20.943 46.047  1   21.867 ? 421  LYS A N   1 
ATOM   3218 C  CA  . LYS A 1 429 ? 15.179  -19.817 45.139  1   20.396 ? 421  LYS A CA  1 
ATOM   3219 C  C   . LYS A 1 429 ? 15.722  -18.539 45.8    1   20.423 ? 421  LYS A C   1 
ATOM   3220 O  O   . LYS A 1 429 ? 15.589  -18.33  47.011  1   18.421 ? 421  LYS A O   1 
ATOM   3221 C  CB  . LYS A 1 429 ? 13.676  -19.635 44.828  1   26.422 ? 421  LYS A CB  1 
ATOM   3222 C  CG  . LYS A 1 429 ? 12.94   -20.664 43.948  1   34.497 ? 421  LYS A CG  1 
ATOM   3223 C  CD  . LYS A 1 429 ? 13.23   -20.366 42.477  1   39.547 ? 421  LYS A CD  1 
ATOM   3224 C  CE  . LYS A 1 429 ? 12.877  -21.384 41.41   1   44.471 ? 421  LYS A CE  1 
ATOM   3225 N  NZ  . LYS A 1 429 ? 11.669  -21.078 40.632  1   48.179 ? 421  LYS A NZ  1 
ATOM   3226 N  N   . ASN A 1 430 ? 16.351  -17.696 44.97   1   17.112 ? 422  ASN A N   1 
ATOM   3227 C  CA  . ASN A 1 430 ? 16.647  -16.318 45.35   1   15.304 ? 422  ASN A CA  1 
ATOM   3228 C  C   . ASN A 1 430 ? 15.392  -15.715 45.986  1   15.173 ? 422  ASN A C   1 
ATOM   3229 O  O   . ASN A 1 430 ? 14.262  -16.059 45.596  1   16.161 ? 422  ASN A O   1 
ATOM   3230 C  CB  . ASN A 1 430 ? 17.101  -15.588 44.1    1   14.617 ? 422  ASN A CB  1 
ATOM   3231 C  CG  . ASN A 1 430 ? 17.194  -14.087 44.276  1   15.107 ? 422  ASN A CG  1 
ATOM   3232 O  OD1 . ASN A 1 430 ? 16.202  -13.391 43.993  1   15.783 ? 422  ASN A OD1 1 
ATOM   3233 N  ND2 . ASN A 1 430 ? 18.369  -13.586 44.637  1   16.215 ? 422  ASN A ND2 1 
ATOM   3234 N  N   . VAL A 1 431 ? 15.59   -14.789 46.941  1   14.545 ? 423  VAL A N   1 
ATOM   3235 C  CA  . VAL A 1 431 ? 14.51   -14.274 47.775  1   14.436 ? 423  VAL A CA  1 
ATOM   3236 C  C   . VAL A 1 431 ? 13.41   -13.614 46.913  1   14.39  ? 423  VAL A C   1 
ATOM   3237 O  O   . VAL A 1 431 ? 12.244  -13.593 47.333  1   16.433 ? 423  VAL A O   1 
ATOM   3238 C  CB  . VAL A 1 431 ? 15.076  -13.315 48.851  1   15.194 ? 423  VAL A CB  1 
ATOM   3239 C  CG1 . VAL A 1 431 ? 15.619  -11.993 48.282  1   15.243 ? 423  VAL A CG1 1 
ATOM   3240 C  CG2 . VAL A 1 431 ? 14.028  -13.007 49.912  1   17.951 ? 423  VAL A CG2 1 
ATOM   3241 N  N   . PHE A 1 432 ? 13.758  -13.048 45.741  1   15.094 ? 424  PHE A N   1 
ATOM   3242 C  CA  . PHE A 1 432 ? 12.75   -12.353 44.934  1   15.659 ? 424  PHE A CA  1 
ATOM   3243 C  C   . PHE A 1 432 ? 11.955  -13.318 44.062  1   14.646 ? 424  PHE A C   1 
ATOM   3244 O  O   . PHE A 1 432 ? 10.992  -12.863 43.428  1   15.133 ? 424  PHE A O   1 
ATOM   3245 C  CB  . PHE A 1 432 ? 13.385  -11.284 44.022  1   15.992 ? 424  PHE A CB  1 
ATOM   3246 C  CG  . PHE A 1 432 ? 14.046  -10.183 44.843  1   15.028 ? 424  PHE A CG  1 
ATOM   3247 C  CD1 . PHE A 1 432 ? 13.285  -9.21   45.463  1   16.698 ? 424  PHE A CD1 1 
ATOM   3248 C  CD2 . PHE A 1 432 ? 15.455  -10.122 44.925  1   16.014 ? 424  PHE A CD2 1 
ATOM   3249 C  CE1 . PHE A 1 432 ? 13.893  -8.223  46.23   1   16.535 ? 424  PHE A CE1 1 
ATOM   3250 C  CE2 . PHE A 1 432 ? 16.056  -9.106  45.71   1   15.846 ? 424  PHE A CE2 1 
ATOM   3251 C  CZ  . PHE A 1 432 ? 15.267  -8.147  46.326  1   15.61  ? 424  PHE A CZ  1 
ATOM   3252 N  N   . GLN A 1 433 ? 12.317  -14.625 44.054  1   16.477 ? 425  GLN A N   1 
ATOM   3253 C  CA  . GLN A 1 433 ? 11.785  -15.525 43.029  1   16.668 ? 425  GLN A CA  1 
ATOM   3254 C  C   . GLN A 1 433 ? 10.915  -16.643 43.605  1   18.727 ? 425  GLN A C   1 
ATOM   3255 O  O   . GLN A 1 433 ? 10.362  -17.419 42.809  1   20.396 ? 425  GLN A O   1 
ATOM   3256 C  CB  . GLN A 1 433 ? 12.943  -16.162 42.25   1   16.762 ? 425  GLN A CB  1 
ATOM   3257 C  CG  . GLN A 1 433 ? 13.866  -15.126 41.6    1   18.175 ? 425  GLN A CG  1 
ATOM   3258 C  CD  . GLN A 1 433 ? 14.865  -15.729 40.645  1   23.335 ? 425  GLN A CD  1 
ATOM   3259 O  OE1 . GLN A 1 433 ? 15.044  -16.943 40.606  1   31.723 ? 425  GLN A OE1 1 
ATOM   3260 N  NE2 . GLN A 1 433 ? 15.518  -14.88  39.867  1   25.242 ? 425  GLN A NE2 1 
ATOM   3261 N  N   . GLY A 1 434 ? 10.74   -16.73  44.911  1   15.19  ? 426  GLY A N   1 
ATOM   3262 C  CA  . GLY A 1 434 ? 9.895   -17.783 45.475  1   17.013 ? 426  GLY A CA  1 
ATOM   3263 C  C   . GLY A 1 434 ? 8.754   -17.283 46.349  1   17.325 ? 426  GLY A C   1 
ATOM   3264 O  O   . GLY A 1 434 ? 8.282   -18.033 47.214  1   18.379 ? 426  GLY A O   1 
ATOM   3265 N  N   . LEU A 1 435 ? 8.355   -16.011 46.163  1   16.325 ? 427  LEU A N   1 
ATOM   3266 C  CA  . LEU A 1 435 ? 7.411   -15.382 47.093  1   16.084 ? 427  LEU A CA  1 
ATOM   3267 C  C   . LEU A 1 435 ? 5.99    -15.78  46.679  1   16.269 ? 427  LEU A C   1 
ATOM   3268 O  O   . LEU A 1 435 ? 5.445   -15.292 45.66   1   16.107 ? 427  LEU A O   1 
ATOM   3269 C  CB  . LEU A 1 435 ? 7.638   -13.864 47.004  1   15.689 ? 427  LEU A CB  1 
ATOM   3270 C  CG  . LEU A 1 435 ? 8.99    -13.38  47.557  1   15.271 ? 427  LEU A CG  1 
ATOM   3271 C  CD1 . LEU A 1 435 ? 9.38    -11.987 47.029  1   17.624 ? 427  LEU A CD1 1 
ATOM   3272 C  CD2 . LEU A 1 435 ? 9.07    -13.395 49.091  1   18.521 ? 427  LEU A CD2 1 
ATOM   3273 N  N   . ASN A 1 436 ? 5.406   -16.7   47.465  1   16.273 ? 428  ASN A N   1 
ATOM   3274 C  CA  . ASN A 1 436 ? 4.116   -17.31  47.147  1   15.716 ? 428  ASN A CA  1 
ATOM   3275 C  C   . ASN A 1 436 ? 3.082   -17.11  48.246  1   14.968 ? 428  ASN A C   1 
ATOM   3276 O  O   . ASN A 1 436 ? 2.027   -17.765 48.251  1   16.212 ? 428  ASN A O   1 
ATOM   3277 C  CB  . ASN A 1 436 ? 4.284   -18.771 46.763  1   15.54  ? 428  ASN A CB  1 
ATOM   3278 C  CG  . ASN A 1 436 ? 4.786   -19.617 47.92   1   18.085 ? 428  ASN A CG  1 
ATOM   3279 O  OD1 . ASN A 1 436 ? 5.237   -19.125 48.971  1   16.615 ? 428  ASN A OD1 1 
ATOM   3280 N  ND2 . ASN A 1 436 ? 4.718   -20.939 47.743  1   22.322 ? 428  ASN A ND2 1 
ATOM   3281 N  N   . GLY A 1 437 ? 3.356   -16.189 49.183  1   14.029 ? 429  GLY A N   1 
ATOM   3282 C  CA  . GLY A 1 437 ? 2.361   -15.843 50.163  1   14.674 ? 429  GLY A CA  1 
ATOM   3283 C  C   . GLY A 1 437 ? 2.529   -14.459 50.76   1   13.132 ? 429  GLY A C   1 
ATOM   3284 O  O   . GLY A 1 437 ? 3.466   -13.717 50.374  1   14.237 ? 429  GLY A O   1 
ATOM   3285 N  N   . LEU A 1 438 ? 1.585   -14.117 51.633  1   13.402 ? 430  LEU A N   1 
ATOM   3286 C  CA  . LEU A 1 438 ? 1.698   -12.905 52.426  1   14.054 ? 430  LEU A CA  1 
ATOM   3287 C  C   . LEU A 1 438 ? 1.617   -13.267 53.897  1   13.792 ? 430  LEU A C   1 
ATOM   3288 O  O   . LEU A 1 438 ? 0.942   -14.247 54.26   1   14.698 ? 430  LEU A O   1 
ATOM   3289 C  CB  . LEU A 1 438 ? 0.59    -11.897 52.121  1   15.109 ? 430  LEU A CB  1 
ATOM   3290 C  CG  . LEU A 1 438 ? 0.424   -11.506 50.645  1   15.248 ? 430  LEU A CG  1 
ATOM   3291 C  CD1 . LEU A 1 438 ? -0.844  -10.68  50.449  1   15.592 ? 430  LEU A CD1 1 
ATOM   3292 C  CD2 . LEU A 1 438 ? 1.654   -10.752 50.132  1   14.826 ? 430  LEU A CD2 1 
ATOM   3293 N  N   . ALA A 1 439 ? 2.233   -12.423 54.726  1   13.998 ? 431  ALA A N   1 
ATOM   3294 C  CA  . ALA A 1 439 ? 2.039   -12.539 56.159  1   14.31  ? 431  ALA A CA  1 
ATOM   3295 C  C   . ALA A 1 439 ? 1.537   -11.229 56.725  1   15.054 ? 431  ALA A C   1 
ATOM   3296 O  O   . ALA A 1 439 ? 1.96    -10.165 56.261  1   14.789 ? 431  ALA A O   1 
ATOM   3297 C  CB  . ALA A 1 439 ? 3.335   -12.933 56.863  1   14.633 ? 431  ALA A CB  1 
ATOM   3298 N  N   . HIS A 1 440 ? 0.619   -11.287 57.7    1   14.126 ? 432  HIS A N   1 
ATOM   3299 C  CA  . HIS A 1 440 ? 0.257   -10.11  58.476  1   13.573 ? 432  HIS A CA  1 
ATOM   3300 C  C   . HIS A 1 440 ? 0.806   -10.333 59.879  1   13.863 ? 432  HIS A C   1 
ATOM   3301 O  O   . HIS A 1 440 ? 0.257   -11.152 60.614  1   16.043 ? 432  HIS A O   1 
ATOM   3302 C  CB  . HIS A 1 440 ? -1.266  -9.89   58.529  1   14.908 ? 432  HIS A CB  1 
ATOM   3303 C  CG  . HIS A 1 440 ? -1.654  -8.639  59.231  1   14.369 ? 432  HIS A CG  1 
ATOM   3304 N  ND1 . HIS A 1 440 ? -2.971  -8.299  59.455  1   15.366 ? 432  HIS A ND1 1 
ATOM   3305 C  CD2 . HIS A 1 440 ? -0.919  -7.651  59.815  1   13.488 ? 432  HIS A CD2 1 
ATOM   3306 C  CE1 . HIS A 1 440 ? -3.025  -7.15   60.084  1   14.581 ? 432  HIS A CE1 1 
ATOM   3307 N  NE2 . HIS A 1 440 ? -1.797  -6.754  60.329  1   15.041 ? 432  HIS A NE2 1 
ATOM   3308 N  N   . TYR A 1 441 ? 1.927   -9.705  60.184  1   14.123 ? 433  TYR A N   1 
ATOM   3309 C  CA  . TYR A 1 441 ? 2.605   -9.769  61.467  1   13.78  ? 433  TYR A CA  1 
ATOM   3310 C  C   . TYR A 1 441 ? 2.125   -8.613  62.325  1   13.756 ? 433  TYR A C   1 
ATOM   3311 O  O   . TYR A 1 441 ? 2.004   -7.477  61.855  1   14.989 ? 433  TYR A O   1 
ATOM   3312 C  CB  . TYR A 1 441 ? 4.119   -9.715  61.22   1   14.91  ? 433  TYR A CB  1 
ATOM   3313 C  CG  . TYR A 1 441 ? 4.92    -9.511  62.5    1   15.176 ? 433  TYR A CG  1 
ATOM   3314 C  CD1 . TYR A 1 441 ? 4.988   -10.548 63.425  1   16.232 ? 433  TYR A CD1 1 
ATOM   3315 C  CD2 . TYR A 1 441 ? 5.487   -8.287  62.857  1   16.255 ? 433  TYR A CD2 1 
ATOM   3316 C  CE1 . TYR A 1 441 ? 5.628   -10.33  64.64   1   15.494 ? 433  TYR A CE1 1 
ATOM   3317 C  CE2 . TYR A 1 441 ? 6.157   -8.076  64.062  1   15.501 ? 433  TYR A CE2 1 
ATOM   3318 C  CZ  . TYR A 1 441 ? 6.225   -9.121  64.961  1   15.774 ? 433  TYR A CZ  1 
ATOM   3319 O  OH  . TYR A 1 441 ? 6.874   -8.965  66.174  1   16.027 ? 433  TYR A OH  1 
ATOM   3320 N  N   . LYS A 1 442 ? 1.838   -8.89   63.613  1   14.871 ? 434  LYS A N   1 
ATOM   3321 C  CA  . LYS A 1 442 ? 1.463   -7.843  64.558  1   15.127 ? 434  LYS A CA  1 
ATOM   3322 C  C   . LYS A 1 442 ? 2.399   -7.922  65.756  1   17.194 ? 434  LYS A C   1 
ATOM   3323 O  O   . LYS A 1 442 ? 2.337   -8.905  66.522  1   17.963 ? 434  LYS A O   1 
ATOM   3324 C  CB  . LYS A 1 442 ? 0.004   -7.978  65.035  1   16.305 ? 434  LYS A CB  1 
ATOM   3325 C  CG  . LYS A 1 442 ? -1.03   -7.69   63.958  1   16.705 ? 434  LYS A CG  1 
ATOM   3326 C  CD  . LYS A 1 442 ? -2.44   -7.838  64.539  1   18.671 ? 434  LYS A CD  1 
ATOM   3327 C  CE  . LYS A 1 442 ? -3.468  -7.659  63.468  1   20.621 ? 434  LYS A CE  1 
ATOM   3328 N  NZ  . LYS A 1 442 ? -4.833  -7.635  64.017  1   22.879 ? 434  LYS A NZ  1 
ATOM   3329 N  N   . ARG A 1 443 ? 3.252   -6.895  65.9    1   15.644 ? 435  ARG A N   1 
ATOM   3330 C  CA  . ARG A 1 443 ? 4.235   -6.896  66.981  1   17.473 ? 435  ARG A CA  1 
ATOM   3331 C  C   . ARG A 1 443 ? 3.529   -6.882  68.342  1   19.341 ? 435  ARG A C   1 
ATOM   3332 O  O   . ARG A 1 443 ? 3.95    -7.639  69.232  1   21.471 ? 435  ARG A O   1 
ATOM   3333 C  CB  . ARG A 1 443 ? 5.156   -5.687  66.83   1   17.02  ? 435  ARG A CB  1 
ATOM   3334 C  CG  . ARG A 1 443 ? 6.229   -5.755  67.922  1   18.514 ? 435  ARG A CG  1 
ATOM   3335 C  CD  . ARG A 1 443 ? 7.223   -4.596  67.793  1   18.847 ? 435  ARG A CD  1 
ATOM   3336 N  NE  . ARG A 1 443 ? 6.565   -3.281  67.766  1   17.931 ? 435  ARG A NE  1 
ATOM   3337 C  CZ  . ARG A 1 443 ? 5.976   -2.62   68.776  1   18.513 ? 435  ARG A CZ  1 
ATOM   3338 N  NH1 . ARG A 1 443 ? 6.136   -3.019  70.059  1   19.472 ? 435  ARG A NH1 1 
ATOM   3339 N  NH2 . ARG A 1 443 ? 5.267   -1.526  68.548  1   17.911 ? 435  ARG A NH2 1 
ATOM   3340 N  N   . LYS A 1 444 ? 2.479   -6.06   68.484  1   16.38  ? 436  LYS A N   1 
ATOM   3341 C  CA  . LYS A 1 444 ? 1.91    -5.874  69.838  1   20.145 ? 436  LYS A CA  1 
ATOM   3342 C  C   . LYS A 1 444 ? 1.312   -7.186  70.328  1   19.774 ? 436  LYS A C   1 
ATOM   3343 O  O   . LYS A 1 444 ? 1.6     -7.571  71.469  1   22.184 ? 436  LYS A O   1 
ATOM   3344 C  CB  . LYS A 1 444 ? 0.915   -4.717  69.895  1   20.685 ? 436  LYS A CB  1 
ATOM   3345 C  CG  . LYS A 1 444 ? 1.651   -3.353  69.835  1   24.787 ? 436  LYS A CG  1 
ATOM   3346 C  CD  . LYS A 1 444 ? 0.709   -2.159  69.699  1   25.726 ? 436  LYS A CD  1 
ATOM   3347 C  CE  . LYS A 1 444 ? 1.509   -0.906  69.725  1   28.202 ? 436  LYS A CE  1 
ATOM   3348 N  NZ  . LYS A 1 444 ? 0.584   0.226   69.593  1   27.605 ? 436  LYS A NZ  1 
ATOM   3349 N  N   . GLU A 1 445 ? 0.556   -7.871  69.467  1   21.059 ? 437  GLU A N   1 
ATOM   3350 C  CA  . GLU A 1 445 ? -0.052  -9.155  69.806  1   20.163 ? 437  GLU A CA  1 
ATOM   3351 C  C   . GLU A 1 445 ? 0.956   -10.305 69.686  1   20.287 ? 437  GLU A C   1 
ATOM   3352 O  O   . GLU A 1 445 ? 0.737   -11.342 70.331  1   24.959 ? 437  GLU A O   1 
ATOM   3353 C  CB  . GLU A 1 445 ? -1.298  -9.448  68.97   1   19.804 ? 437  GLU A CB  1 
ATOM   3354 C  CG  . GLU A 1 445 ? -2.479  -8.514  69.21   1   23.879 ? 437  GLU A CG  1 
ATOM   3355 C  CD  . GLU A 1 445 ? -2.502  -7.207  68.462  1   25.219 ? 437  GLU A CD  1 
ATOM   3356 O  OE1 . GLU A 1 445 ? -1.466  -6.855  67.826  1   24.615 ? 437  GLU A OE1 1 
ATOM   3357 O  OE2 . GLU A 1 445 ? -3.524  -6.51   68.528  1   27.73  ? 437  GLU A OE2 1 
ATOM   3358 N  N   . GLY A 1 446 ? 2.015   -10.169 68.878  1   21.995 ? 438  GLY A N   1 
ATOM   3359 C  CA  . GLY A 1 446 ? 3.035   -11.192 68.691  1   19.897 ? 438  GLY A CA  1 
ATOM   3360 C  C   . GLY A 1 446 ? 2.629   -12.293 67.7    1   23.804 ? 438  GLY A C   1 
ATOM   3361 O  O   . GLY A 1 446 ? 3.286   -13.328 67.658  1   29.652 ? 438  GLY A O   1 
ATOM   3362 N  N   . THR A 1 447 ? 1.585   -12.041 66.901  1   23.485 ? 439  THR A N   1 
ATOM   3363 C  CA  . THR A 1 447 ? 0.943   -13.031 66.059  1   20.611 ? 439  THR A CA  1 
ATOM   3364 C  C   . THR A 1 447 ? 1.348   -12.818 64.609  1   18.618 ? 439  THR A C   1 
ATOM   3365 O  O   . THR A 1 447 ? 1.602   -11.68  64.212  1   18.03  ? 439  THR A O   1 
ATOM   3366 C  CB  . THR A 1 447 ? -0.583  -12.855 66.161  1   22.336 ? 439  THR A CB  1 
ATOM   3367 O  OG1 . THR A 1 447 ? -1.05   -11.558 65.788  1   24.42  ? 439  THR A OG1 1 
ATOM   3368 C  CG2 . THR A 1 447 ? -1.164  -13.165 67.533  1   24.93  ? 439  THR A CG2 1 
ATOM   3369 N  N   . THR A 1 448 ? 1.279   -13.891 63.823  1   16.749 ? 440  THR A N   1 
ATOM   3370 C  CA  . THR A 1 448 ? 1.447   -13.83  62.375  1   16.718 ? 440  THR A CA  1 
ATOM   3371 C  C   . THR A 1 448 ? 0.317   -14.632 61.741  1   18.912 ? 440  THR A C   1 
ATOM   3372 O  O   . THR A 1 448 ? 0.083   -15.784 62.124  1   20.408 ? 440  THR A O   1 
ATOM   3373 C  CB  . THR A 1 448 ? 2.807   -14.346 61.909  1   19.865 ? 440  THR A CB  1 
ATOM   3374 O  OG1 . THR A 1 448 ? 3.837   -13.699 62.656  1   21.196 ? 440  THR A OG1 1 
ATOM   3375 C  CG2 . THR A 1 448 ? 3.028   -14.077 60.423  1   20.359 ? 440  THR A CG2 1 
ATOM   3376 N  N   . GLU A 1 449 ? -0.385  -14.025 60.782  1   16.757 ? 441  GLU A N   1 
ATOM   3377 C  CA  . GLU A 1 449 ? -1.371  -14.687 59.936  1   16.888 ? 441  GLU A CA  1 
ATOM   3378 C  C   . GLU A 1 449 ? -0.83   -14.8   58.519  1   18.082 ? 441  GLU A C   1 
ATOM   3379 O  O   . GLU A 1 449 ? -0.005  -13.989 58.103  1   17.322 ? 441  GLU A O   1 
ATOM   3380 C  CB  . GLU A 1 449 ? -2.712  -13.947 59.955  1   18.589 ? 441  GLU A CB  1 
ATOM   3381 C  CG  . GLU A 1 449 ? -3.216  -13.783 61.392  1   20.799 ? 441  GLU A CG  1 
ATOM   3382 C  CD  . GLU A 1 449 ? -4.35   -12.8   61.546  1   26.276 ? 441  GLU A CD  1 
ATOM   3383 O  OE1 . GLU A 1 449 ? -4.077  -11.634 61.885  1   30.959 ? 441  GLU A OE1 1 
ATOM   3384 O  OE2 . GLU A 1 449 ? -5.498  -13.235 61.353  1   28.698 ? 441  GLU A OE2 1 
ATOM   3385 N  N   . TRP A 1 450 ? -1.309  -15.781 57.755  1   16.585 ? 442  TRP A N   1 
ATOM   3386 C  CA  . TRP A 1 450 ? -0.687  -16.197 56.498  1   16.292 ? 442  TRP A CA  1 
ATOM   3387 C  C   . TRP A 1 450 ? -1.74   -16.344 55.414  1   17.358 ? 442  TRP A C   1 
ATOM   3388 O  O   . TRP A 1 450 ? -2.824  -16.885 55.647  1   18.442 ? 442  TRP A O   1 
ATOM   3389 C  CB  . TRP A 1 450 ? 0.05    -17.531 56.65   1   17.418 ? 442  TRP A CB  1 
ATOM   3390 C  CG  . TRP A 1 450 ? 1.07    -17.534 57.764  1   17.354 ? 442  TRP A CG  1 
ATOM   3391 C  CD1 . TRP A 1 450 ? 0.858   -17.825 59.085  1   19.325 ? 442  TRP A CD1 1 
ATOM   3392 C  CD2 . TRP A 1 450 ? 2.482   -17.264 57.619  1   17.241 ? 442  TRP A CD2 1 
ATOM   3393 N  NE1 . TRP A 1 450 ? 2.038   -17.718 59.779  1   18.972 ? 442  TRP A NE1 1 
ATOM   3394 C  CE2 . TRP A 1 450 ? 3.051   -17.394 58.908  1   16.944 ? 442  TRP A CE2 1 
ATOM   3395 C  CE3 . TRP A 1 450 ? 3.308   -16.943 56.538  1   18.941 ? 442  TRP A CE3 1 
ATOM   3396 C  CZ2 . TRP A 1 450 ? 4.422   -17.206 59.145  1   19.786 ? 442  TRP A CZ2 1 
ATOM   3397 C  CZ3 . TRP A 1 450 ? 4.653   -16.778 56.764  1   19.234 ? 442  TRP A CZ3 1 
ATOM   3398 C  CH2 . TRP A 1 450 ? 5.213   -16.921 58.042  1   19.169 ? 442  TRP A CH2 1 
ATOM   3399 N  N   . TYR A 1 451 ? -1.43   -15.805 54.234  1   14.929 ? 443  TYR A N   1 
ATOM   3400 C  CA  . TYR A 1 451 ? -2.21   -15.98  53.022  1   15.889 ? 443  TYR A CA  1 
ATOM   3401 C  C   . TYR A 1 451 ? -1.365  -16.746 52.012  1   15.544 ? 443  TYR A C   1 
ATOM   3402 O  O   . TYR A 1 451 ? -0.22   -16.37  51.736  1   15.906 ? 443  TYR A O   1 
ATOM   3403 C  CB  . TYR A 1 451 ? -2.571  -14.598 52.425  1   15.408 ? 443  TYR A CB  1 
ATOM   3404 C  CG  . TYR A 1 451 ? -3.352  -14.806 51.127  1   15.981 ? 443  TYR A CG  1 
ATOM   3405 C  CD1 . TYR A 1 451 ? -4.705  -15.127 51.174  1   15.548 ? 443  TYR A CD1 1 
ATOM   3406 C  CD2 . TYR A 1 451 ? -2.77   -14.64  49.865  1   15.101 ? 443  TYR A CD2 1 
ATOM   3407 C  CE1 . TYR A 1 451 ? -5.436  -15.376 50.009  1   15.324 ? 443  TYR A CE1 1 
ATOM   3408 C  CE2 . TYR A 1 451 ? -3.485  -14.827 48.684  1   15.546 ? 443  TYR A CE2 1 
ATOM   3409 C  CZ  . TYR A 1 451 ? -4.83   -15.233 48.76   1   15.887 ? 443  TYR A CZ  1 
ATOM   3410 O  OH  . TYR A 1 451 ? -5.562  -15.458 47.615  1   15.947 ? 443  TYR A OH  1 
ATOM   3411 N  N   . TYR A 1 452 ? -1.914  -17.853 51.459  1   16.451 ? 444  TYR A N   1 
ATOM   3412 C  CA  . TYR A 1 452 ? -1.22   -18.605 50.419  1   15.475 ? 444  TYR A CA  1 
ATOM   3413 C  C   . TYR A 1 452 ? -1.739  -18.194 49.038  1   17.199 ? 444  TYR A C   1 
ATOM   3414 O  O   . TYR A 1 452 ? -2.945  -18.256 48.789  1   18.678 ? 444  TYR A O   1 
ATOM   3415 C  CB  . TYR A 1 452 ? -1.461  -20.12  50.667  1   17.41  ? 444  TYR A CB  1 
ATOM   3416 C  CG  . TYR A 1 452 ? -0.821  -21.021 49.618  1   17.013 ? 444  TYR A CG  1 
ATOM   3417 C  CD1 . TYR A 1 452 ? 0.542   -20.977 49.346  1   19.465 ? 444  TYR A CD1 1 
ATOM   3418 C  CD2 . TYR A 1 452 ? -1.603  -21.929 48.9    1   21.456 ? 444  TYR A CD2 1 
ATOM   3419 C  CE1 . TYR A 1 452 ? 1.13    -21.813 48.403  1   20.372 ? 444  TYR A CE1 1 
ATOM   3420 C  CE2 . TYR A 1 452 ? -1.022  -22.78  47.96   1   19.357 ? 444  TYR A CE2 1 
ATOM   3421 C  CZ  . TYR A 1 452 ? 0.332   -22.715 47.714  1   21.308 ? 444  TYR A CZ  1 
ATOM   3422 O  OH  . TYR A 1 452 ? 0.941   -23.551 46.814  1   28.295 ? 444  TYR A OH  1 
ATOM   3423 N  N   . ALA A 1 453 ? -0.827  -17.869 48.121  1   15.752 ? 445  ALA A N   1 
ATOM   3424 C  CA  . ALA A 1 453 ? -1.254  -17.37  46.817  1   16.313 ? 445  ALA A CA  1 
ATOM   3425 C  C   . ALA A 1 453 ? -1.957  -18.448 45.982  1   19.016 ? 445  ALA A C   1 
ATOM   3426 O  O   . ALA A 1 453 ? -2.772  -18.111 45.114  1   17.812 ? 445  ALA A O   1 
ATOM   3427 C  CB  . ALA A 1 453 ? -0.066  -16.839 46.029  1   18.083 ? 445  ALA A CB  1 
ATOM   3428 N  N   . GLY A 1 454 ? -1.536  -19.705 46.168  1   19.672 ? 446  GLY A N   1 
ATOM   3429 C  CA  . GLY A 1 454 ? -2.083  -20.818 45.411  1   21.355 ? 446  GLY A CA  1 
ATOM   3430 C  C   . GLY A 1 454 ? -0.965  -21.626 44.756  1   19.451 ? 446  GLY A C   1 
ATOM   3431 O  O   . GLY A 1 454 ? 0.144   -21.151 44.52   1   21.621 ? 446  GLY A O   1 
ATOM   3432 N  N   . ASP A 1 455 ? -1.281  -22.892 44.395  1   24.224 ? 447  ASP A N   1 
ATOM   3433 C  CA  . ASP A 1 455 ? -0.353  -23.691 43.602  1   24.114 ? 447  ASP A CA  1 
ATOM   3434 C  C   . ASP A 1 455 ? -0.138  -23.035 42.242  1   23.475 ? 447  ASP A C   1 
ATOM   3435 O  O   . ASP A 1 455 ? -1.09   -22.506 41.681  1   27.972 ? 447  ASP A O   1 
ATOM   3436 C  CB  . ASP A 1 455 ? -0.919  -25.086 43.389  1   32.113 ? 447  ASP A CB  1 
ATOM   3437 C  CG  . ASP A 1 455 ? -0.593  -26.073 44.502  1   47.598 ? 447  ASP A CG  1 
ATOM   3438 O  OD1 . ASP A 1 455 ? -0.372  -25.624 45.691  1   40.881 ? 447  ASP A OD1 1 
ATOM   3439 O  OD2 . ASP A 1 455 ? -0.494  -27.274 44.163  1   63.027 ? 447  ASP A OD2 1 
ATOM   3440 N  N   . ASN A 1 456 ? 1.121   -23.059 41.788  1   25.303 ? 448  ASN A N   1 
ATOM   3441 C  CA  . ASN A 1 456 ? 1.589   -22.49  40.529  1   26.675 ? 448  ASN A CA  1 
ATOM   3442 C  C   . ASN A 1 456 ? 1.282   -20.983 40.478  1   26.09  ? 448  ASN A C   1 
ATOM   3443 O  O   . ASN A 1 456 ? 0.962   -20.431 39.417  1   24.953 ? 448  ASN A O   1 
ATOM   3444 C  CB  . ASN A 1 456 ? 1.017   -23.192 39.292  1   33.981 ? 448  ASN A CB  1 
ATOM   3445 C  CG  . ASN A 1 456 ? 1.302   -24.678 39.289  1   39.486 ? 448  ASN A CG  1 
ATOM   3446 O  OD1 . ASN A 1 456 ? 0.361   -25.474 39.384  1   43.39  ? 448  ASN A OD1 1 
ATOM   3447 N  ND2 . ASN A 1 456 ? 2.569   -25.061 39.213  1   42.607 ? 448  ASN A ND2 1 
ATOM   3448 N  N   . CYS A 1 457 ? 1.356   -20.338 41.646  1   20.345 ? 449  CYS A N   1 
ATOM   3449 C  CA  . CYS A 1 457 ? 1.163   -18.888 41.74   1   18.145 ? 449  CYS A CA  1 
ATOM   3450 C  C   . CYS A 1 457 ? 2.341   -18.262 42.471  1   18.455 ? 449  CYS A C   1 
ATOM   3451 O  O   . CYS A 1 457 ? 2.972   -18.874 43.354  1   20.618 ? 449  CYS A O   1 
ATOM   3452 C  CB  . CYS A 1 457 ? -0.079  -18.527 42.522  1   17.595 ? 449  CYS A CB  1 
ATOM   3453 S  SG  . CYS A 1 457 ? -1.606  -19.076 41.722  1   22.309 ? 449  CYS A SG  1 
ATOM   3454 N  N   . LEU A 1 458 ? 2.643   -17.01  42.112  1   15.788 ? 450  LEU A N   1 
ATOM   3455 C  CA  . LEU A 1 458 ? 3.443   -16.113 42.93   1   15.926 ? 450  LEU A CA  1 
ATOM   3456 C  C   . LEU A 1 458 ? 2.535   -14.947 43.31   1   15.88  ? 450  LEU A C   1 
ATOM   3457 O  O   . LEU A 1 458 ? 1.479   -14.726 42.691  1   16.573 ? 450  LEU A O   1 
ATOM   3458 C  CB  . LEU A 1 458 ? 4.716   -15.715 42.182  1   17.756 ? 450  LEU A CB  1 
ATOM   3459 C  CG  . LEU A 1 458 ? 5.704   -16.865 41.864  1   19.8   ? 450  LEU A CG  1 
ATOM   3460 C  CD1 . LEU A 1 458 ? 6.844   -16.372 40.951  1   20.439 ? 450  LEU A CD1 1 
ATOM   3461 C  CD2 . LEU A 1 458 ? 6.343   -17.482 43.114  1   19.498 ? 450  LEU A CD2 1 
ATOM   3462 N  N   . ILE A 1 459 ? 2.936   -14.25  44.38   1   14.779 ? 451  ILE A N   1 
ATOM   3463 C  CA  . ILE A 1 459 ? 2.22    -13.048 44.799  1   13.601 ? 451  ILE A CA  1 
ATOM   3464 C  C   . ILE A 1 459 ? 3.271   -11.981 45.1    1   13.071 ? 451  ILE A C   1 
ATOM   3465 O  O   . ILE A 1 459 ? 4.404   -12.271 45.514  1   12.733 ? 451  ILE A O   1 
ATOM   3466 C  CB  . ILE A 1 459 ? 1.254   -13.362 45.951  1   12.36  ? 451  ILE A CB  1 
ATOM   3467 C  CG1 . ILE A 1 459 ? 0.322   -12.163 46.282  1   13.935 ? 451  ILE A CG1 1 
ATOM   3468 C  CG2 . ILE A 1 459 ? 2.028   -13.777 47.208  1   12.575 ? 451  ILE A CG2 1 
ATOM   3469 C  CD1 . ILE A 1 459 ? -0.884  -12.594 47.124  1   15.291 ? 451  ILE A CD1 1 
ATOM   3470 N  N   . GLN A 1 460 ? 2.925   -10.733 44.754  1   13.184 ? 452  GLN A N   1 
ATOM   3471 C  CA  . GLN A 1 460 ? 3.856   -9.607  44.839  1   12.373 ? 452  GLN A CA  1 
ATOM   3472 C  C   . GLN A 1 460 ? 3.557   -8.762  46.089  1   12.528 ? 452  GLN A C   1 
ATOM   3473 O  O   . GLN A 1 460 ? 2.73    -9.143  46.937  1   12.633 ? 452  GLN A O   1 
ATOM   3474 C  CB  . GLN A 1 460 ? 3.761   -8.8    43.527  1   12.235 ? 452  GLN A CB  1 
ATOM   3475 C  CG  . GLN A 1 460 ? 4.348   -9.609  42.364  1   13.485 ? 452  GLN A CG  1 
ATOM   3476 C  CD  . GLN A 1 460 ? 3.877   -9.086  41.028  1   13.04  ? 452  GLN A CD  1 
ATOM   3477 O  OE1 . GLN A 1 460 ? 3.975   -7.887  40.714  1   14.277 ? 452  GLN A OE1 1 
ATOM   3478 N  NE2 . GLN A 1 460 ? 3.337   -9.986  40.2    1   14.458 ? 452  GLN A NE2 1 
ATOM   3479 N  N   . GLU A 1 461 ? 4.276   -7.631  46.244  1   12.44  ? 453  GLU A N   1 
ATOM   3480 C  CA  . GLU A 1 461 ? 4.264   -6.851  47.495  1   10.785 ? 453  GLU A CA  1 
ATOM   3481 C  C   . GLU A 1 461 ? 2.823   -6.456  47.843  1   10.803 ? 453  GLU A C   1 
ATOM   3482 O  O   . GLU A 1 461 ? 2.077   -5.963  46.982  1   11.608 ? 453  GLU A O   1 
ATOM   3483 C  CB  . GLU A 1 461 ? 5.04    -5.567  47.197  1   10.128 ? 453  GLU A CB  1 
ATOM   3484 C  CG  . GLU A 1 461 ? 4.963   -4.59   48.368  1   11.607 ? 453  GLU A CG  1 
ATOM   3485 C  CD  . GLU A 1 461 ? 5.548   -3.269  47.941  1   11.965 ? 453  GLU A CD  1 
ATOM   3486 O  OE1 . GLU A 1 461 ? 5.091   -2.745  46.912  1   12.143 ? 453  GLU A OE1 1 
ATOM   3487 O  OE2 . GLU A 1 461 ? 6.428   -2.716  48.627  1   12.54  ? 453  GLU A OE2 1 
ATOM   3488 N  N   . PRO A 1 462 ? 2.421   -6.618  49.115  1   11.596 ? 454  PRO A N   1 
ATOM   3489 C  CA  . PRO A 1 462 ? 1.08    -6.182  49.546  1   12.023 ? 454  PRO A CA  1 
ATOM   3490 C  C   . PRO A 1 462 ? 1.027   -4.68   49.828  1   11.673 ? 454  PRO A C   1 
ATOM   3491 O  O   . PRO A 1 462 ? 2.029   -4.062  50.265  1   12.202 ? 454  PRO A O   1 
ATOM   3492 C  CB  . PRO A 1 462 ? 0.921   -7.003  50.835  1   12.153 ? 454  PRO A CB  1 
ATOM   3493 C  CG  . PRO A 1 462 ? 2.334   -7.103  51.414  1   11.8   ? 454  PRO A CG  1 
ATOM   3494 C  CD  . PRO A 1 462 ? 3.237   -7.245  50.162  1   12.287 ? 454  PRO A CD  1 
ATOM   3495 N  N   . VAL A 1 463 ? -0.172  -4.13   49.642  1   11.392 ? 455  VAL A N   1 
ATOM   3496 C  CA  . VAL A 1 463 ? -0.481  -2.79   50.131  1   11.031 ? 455  VAL A CA  1 
ATOM   3497 C  C   . VAL A 1 463 ? -1.738  -2.833  50.984  1   13.069 ? 455  VAL A C   1 
ATOM   3498 O  O   . VAL A 1 463 ? -2.611  -3.699  50.78   1   13.082 ? 455  VAL A O   1 
ATOM   3499 C  CB  . VAL A 1 463 ? -0.646  -1.772  48.98   1   10.45  ? 455  VAL A CB  1 
ATOM   3500 C  CG1 . VAL A 1 463 ? 0.646   -1.683  48.109  1   11.391 ? 455  VAL A CG1 1 
ATOM   3501 C  CG2 . VAL A 1 463 ? -1.817  -2.089  48.049  1   11.438 ? 455  VAL A CG2 1 
ATOM   3502 N  N   . PHE A 1 464 ? -1.865  -1.864  51.887  1   12.56  ? 456  PHE A N   1 
ATOM   3503 C  CA  . PHE A 1 464 ? -2.986  -1.875  52.841  1   12.937 ? 456  PHE A CA  1 
ATOM   3504 C  C   . PHE A 1 464 ? -3.844  -0.609  52.686  1   13.908 ? 456  PHE A C   1 
ATOM   3505 O  O   . PHE A 1 464 ? -3.345  0.506   52.478  1   13.421 ? 456  PHE A O   1 
ATOM   3506 C  CB  . PHE A 1 464 ? -2.417  -1.952  54.267  1   12.973 ? 456  PHE A CB  1 
ATOM   3507 C  CG  . PHE A 1 464 ? -3.441  -1.74   55.365  1   13.215 ? 456  PHE A CG  1 
ATOM   3508 C  CD1 . PHE A 1 464 ? -4.295  -2.778  55.73   1   14.162 ? 456  PHE A CD1 1 
ATOM   3509 C  CD2 . PHE A 1 464 ? -3.527  -0.516  56.023  1   13.673 ? 456  PHE A CD2 1 
ATOM   3510 C  CE1 . PHE A 1 464 ? -5.224  -2.586  56.762  1   13.868 ? 456  PHE A CE1 1 
ATOM   3511 C  CE2 . PHE A 1 464 ? -4.454  -0.331  57.046  1   15.03  ? 456  PHE A CE2 1 
ATOM   3512 C  CZ  . PHE A 1 464 ? -5.307  -1.354  57.396  1   13.939 ? 456  PHE A CZ  1 
ATOM   3513 N  N   . SER A 1 465 ? -5.152  -0.822  52.795  1   13.592 ? 457  SER A N   1 
ATOM   3514 C  CA  . SER A 1 465 ? -6.074  0.311   52.847  1   14.49  ? 457  SER A CA  1 
ATOM   3515 C  C   . SER A 1 465 ? -6.928  0.148   54.106  1   14.935 ? 457  SER A C   1 
ATOM   3516 O  O   . SER A 1 465 ? -7.584  -0.884  54.231  1   14.301 ? 457  SER A O   1 
ATOM   3517 C  CB  . SER A 1 465 ? -6.976  0.353   51.609  1   14.043 ? 457  SER A CB  1 
ATOM   3518 O  OG  . SER A 1 465 ? -7.962  1.389   51.725  1   17.548 ? 457  SER A OG  1 
ATOM   3519 N  N   . PRO A 1 466 ? -6.976  1.136   55.032  1   14.811 ? 458  PRO A N   1 
ATOM   3520 C  CA  . PRO A 1 466 ? -7.8    0.956   56.251  1   14.556 ? 458  PRO A CA  1 
ATOM   3521 C  C   . PRO A 1 466 ? -9.292  0.869   55.941  1   14.237 ? 458  PRO A C   1 
ATOM   3522 O  O   . PRO A 1 466 ? -9.756  1.512   54.993  1   16.48  ? 458  PRO A O   1 
ATOM   3523 C  CB  . PRO A 1 466 ? -7.443  2.169   57.148  1   16.757 ? 458  PRO A CB  1 
ATOM   3524 C  CG  . PRO A 1 466 ? -6.904  3.183   56.194  1   18.223 ? 458  PRO A CG  1 
ATOM   3525 C  CD  . PRO A 1 466 ? -6.274  2.432   54.975  1   16.443 ? 458  PRO A CD  1 
ATOM   3526 N  N   . ARG A 1 467 ? -10.019 0.131   56.786  1   15.408 ? 459  ARG A N   1 
ATOM   3527 C  CA  . ARG A 1 467 ? -11.448 -0.053  56.532  1   15.936 ? 459  ARG A CA  1 
ATOM   3528 C  C   . ARG A 1 467 ? -12.167 1.304   56.526  1   17.245 ? 459  ARG A C   1 
ATOM   3529 O  O   . ARG A 1 467 ? -13.093 1.497   55.735  1   19.392 ? 459  ARG A O   1 
ATOM   3530 C  CB  . ARG A 1 467 ? -12.006 -0.929  57.661  1   16.797 ? 459  ARG A CB  1 
ATOM   3531 C  CG  . ARG A 1 467 ? -13.426 -1.403  57.327  1   17.978 ? 459  ARG A CG  1 
ATOM   3532 C  CD  . ARG A 1 467 ? -13.945 -2.356  58.441  1   16.638 ? 459  ARG A CD  1 
ATOM   3533 N  NE  . ARG A 1 467 ? -13.032 -3.46   58.767  1   17.081 ? 459  ARG A NE  1 
ATOM   3534 C  CZ  . ARG A 1 467 ? -12.79  -4.522  57.973  1   16.285 ? 459  ARG A CZ  1 
ATOM   3535 N  NH1 . ARG A 1 467 ? -13.595 -4.807  56.947  1   18.041 ? 459  ARG A NH1 1 
ATOM   3536 N  NH2 . ARG A 1 467 ? -11.722 -5.305  58.217  1   17.448 ? 459  ARG A NH2 1 
ATOM   3537 N  N   . SER A 1 468 ? -11.735 2.24    57.386  1   18.38  ? 460  SER A N   1 
ATOM   3538 C  CA  . SER A 1 468 ? -12.141 3.644   57.43   1   19.917 ? 460  SER A CA  1 
ATOM   3539 C  C   . SER A 1 468 ? -10.998 4.438   58.064  1   20.479 ? 460  SER A C   1 
ATOM   3540 O  O   . SER A 1 468 ? -10.067 3.855   58.608  1   20.925 ? 460  SER A O   1 
ATOM   3541 C  CB  . SER A 1 468 ? -13.44  3.821   58.266  1   22.01  ? 460  SER A CB  1 
ATOM   3542 O  OG  . SER A 1 468 ? -13.181 3.398   59.602  1   22.796 ? 460  SER A OG  1 
ATOM   3543 N  N   . LYS A 1 469 ? -11.097 5.787   58.022  1   24.025 ? 461  LYS A N   1 
ATOM   3544 C  CA  . LYS A 1 469 ? -10.012 6.652   58.491  1   26.101 ? 461  LYS A CA  1 
ATOM   3545 C  C   . LYS A 1 469 ? -9.663  6.365   59.951  1   25.355 ? 461  LYS A C   1 
ATOM   3546 O  O   . LYS A 1 469 ? -8.476  6.447   60.298  1   24.693 ? 461  LYS A O   1 
ATOM   3547 C  CB  . LYS A 1 469 ? -10.248 8.146   58.201  1   32.943 ? 461  LYS A CB  1 
ATOM   3548 C  CG  . LYS A 1 469 ? -9.97   8.526   56.738  1   45.171 ? 461  LYS A CG  1 
ATOM   3549 C  CD  . LYS A 1 469 ? -10.44  9.892   56.242  1   51.94  ? 461  LYS A CD  1 
ATOM   3550 C  CE  . LYS A 1 469 ? -9.7    11.097  56.752  1   56.318 ? 461  LYS A CE  1 
ATOM   3551 N  NZ  . LYS A 1 469 ? -8.285  11.073  56.369  1   53.314 ? 461  LYS A NZ  1 
ATOM   3552 N  N   . ASP A 1 470 ? -10.663 5.999   60.785  1   24.014 ? 462  ASP A N   1 
ATOM   3553 C  CA  . ASP A 1 470 ? -10.385 5.744   62.197  1   24.24  ? 462  ASP A CA  1 
ATOM   3554 C  C   . ASP A 1 470 ? -10.515 4.276   62.583  1   24.695 ? 462  ASP A C   1 
ATOM   3555 O  O   . ASP A 1 470 ? -10.582 3.945   63.778  1   25.857 ? 462  ASP A O   1 
ATOM   3556 C  CB  . ASP A 1 470 ? -11.217 6.631   63.119  1   38.13  ? 462  ASP A CB  1 
ATOM   3557 C  CG  . ASP A 1 470 ? -11.152 8.131   62.869  1   48.665 ? 462  ASP A CG  1 
ATOM   3558 O  OD1 . ASP A 1 470 ? -10.024 8.686   62.812  1   55.062 ? 462  ASP A OD1 1 
ATOM   3559 O  OD2 . ASP A 1 470 ? -12.241 8.736   62.754  1   57.726 ? 462  ASP A OD2 1 
ATOM   3560 N  N   . ALA A 1 471 ? -10.429 3.366   61.592  1   20.64  ? 463  ALA A N   1 
ATOM   3561 C  CA  . ALA A 1 471 ? -10.308 1.944   61.911  1   19.026 ? 463  ALA A CA  1 
ATOM   3562 C  C   . ALA A 1 471 ? -9.053  1.697   62.759  1   17.977 ? 463  ALA A C   1 
ATOM   3563 O  O   . ALA A 1 471 ? -8.075  2.444   62.629  1   19.077 ? 463  ALA A O   1 
ATOM   3564 C  CB  . ALA A 1 471 ? -10.305 1.102   60.643  1   18.396 ? 463  ALA A CB  1 
ATOM   3565 N  N   . PRO A 1 472 ? -9.017  0.646   63.599  1   17.821 ? 464  PRO A N   1 
ATOM   3566 C  CA  . PRO A 1 472 ? -7.8    0.288   64.339  1   17.49  ? 464  PRO A CA  1 
ATOM   3567 C  C   . PRO A 1 472 ? -6.648  -0.009  63.366  1   17.372 ? 464  PRO A C   1 
ATOM   3568 O  O   . PRO A 1 472 ? -6.874  -0.334  62.183  1   17.575 ? 464  PRO A O   1 
ATOM   3569 C  CB  . PRO A 1 472 ? -8.208  -0.994  65.119  1   20.274 ? 464  PRO A CB  1 
ATOM   3570 C  CG  . PRO A 1 472 ? -9.714  -0.906  65.208  1   20.671 ? 464  PRO A CG  1 
ATOM   3571 C  CD  . PRO A 1 472 ? -10.168 -0.236  63.946  1   19.208 ? 464  PRO A CD  1 
ATOM   3572 N  N   . GLU A 1 473 ? -5.427  0.088   63.902  1   17.698 ? 465  GLU A N   1 
ATOM   3573 C  CA  . GLU A 1 473 ? -4.249  -0.211  63.073  1   16.257 ? 465  GLU A CA  1 
ATOM   3574 C  C   . GLU A 1 473 ? -4.373  -1.591  62.439  1   16.233 ? 465  GLU A C   1 
ATOM   3575 O  O   . GLU A 1 473 ? -4.7    -2.582  63.098  1   16.222 ? 465  GLU A O   1 
ATOM   3576 C  CB  . GLU A 1 473 ? -3.022  -0.208  63.975  1   15.114 ? 465  GLU A CB  1 
ATOM   3577 C  CG  . GLU A 1 473 ? -1.743  -0.457  63.153  1   15.235 ? 465  GLU A CG  1 
ATOM   3578 C  CD  . GLU A 1 473 ? -0.456  -0.339  63.918  1   19.025 ? 465  GLU A CD  1 
ATOM   3579 O  OE1 . GLU A 1 473 ? -0.462  -0.009  65.134  1   17.659 ? 465  GLU A OE1 1 
ATOM   3580 O  OE2 . GLU A 1 473 ? 0.57    -0.63   63.27   1   15.777 ? 465  GLU A OE2 1 
ATOM   3581 N  N   . GLY A 1 474 ? -4.109  -1.64   61.12   1   14.494 ? 466  GLY A N   1 
ATOM   3582 C  CA  . GLY A 1 474 ? -4.077  -2.907  60.386  1   13.708 ? 466  GLY A CA  1 
ATOM   3583 C  C   . GLY A 1 474 ? -5.462  -3.532  60.214  1   14.795 ? 466  GLY A C   1 
ATOM   3584 O  O   . GLY A 1 474 ? -5.494  -4.716  59.859  1   16.881 ? 466  GLY A O   1 
ATOM   3585 N  N   . ASP A 1 475 ? -6.555  -2.774  60.441  1   14.294 ? 467  ASP A N   1 
ATOM   3586 C  CA  . ASP A 1 475 ? -7.896  -3.259  60.112  1   15.3   ? 467  ASP A CA  1 
ATOM   3587 C  C   . ASP A 1 475 ? -8.373  -2.672  58.798  1   15.163 ? 467  ASP A C   1 
ATOM   3588 O  O   . ASP A 1 475 ? -8.539  -1.462  58.666  1   15.955 ? 467  ASP A O   1 
ATOM   3589 C  CB  . ASP A 1 475 ? -8.895  -2.893  61.223  1   15.832 ? 467  ASP A CB  1 
ATOM   3590 C  CG  . ASP A 1 475 ? -10.294 -3.398  60.913  1   18.24  ? 467  ASP A CG  1 
ATOM   3591 O  OD1 . ASP A 1 475 ? -10.432 -4.613  60.715  1   20.161 ? 467  ASP A OD1 1 
ATOM   3592 O  OD2 . ASP A 1 475 ? -11.182 -2.571  60.836  1   22.952 ? 467  ASP A OD2 1 
ATOM   3593 N  N   . GLY A 1 476 ? -8.558  -3.569  57.82   1   14.12  ? 468  GLY A N   1 
ATOM   3594 C  CA  . GLY A 1 476 ? -8.981  -3.103  56.511  1   14.294 ? 468  GLY A CA  1 
ATOM   3595 C  C   . GLY A 1 476 ? -8.673  -4.159  55.459  1   14.181 ? 468  GLY A C   1 
ATOM   3596 O  O   . GLY A 1 476 ? -8.907  -5.337  55.664  1   13.919 ? 468  GLY A O   1 
ATOM   3597 N  N   . PHE A 1 477 ? -8.121  -3.703  54.317  1   13.019 ? 469  PHE A N   1 
ATOM   3598 C  CA  . PHE A 1 477 ? -7.975  -4.598  53.187  1   13.628 ? 469  PHE A CA  1 
ATOM   3599 C  C   . PHE A 1 477 ? -6.508  -4.599  52.745  1   13.635 ? 469  PHE A C   1 
ATOM   3600 O  O   . PHE A 1 477 ? -5.851  -3.539  52.752  1   14.358 ? 469  PHE A O   1 
ATOM   3601 C  CB  . PHE A 1 477 ? -8.875  -4.076  52.038  1   15.084 ? 469  PHE A CB  1 
ATOM   3602 C  CG  . PHE A 1 477 ? -10.335 -4.072  52.486  1   14.603 ? 469  PHE A CG  1 
ATOM   3603 C  CD1 . PHE A 1 477 ? -11.057 -5.269  52.515  1   15.857 ? 469  PHE A CD1 1 
ATOM   3604 C  CD2 . PHE A 1 477 ? -10.903 -2.874  52.97   1   18.915 ? 469  PHE A CD2 1 
ATOM   3605 C  CE1 . PHE A 1 477 ? -12.376 -5.26   53.04   1   18.578 ? 469  PHE A CE1 1 
ATOM   3606 C  CE2 . PHE A 1 477 ? -12.214 -2.878  53.457  1   19.027 ? 469  PHE A CE2 1 
ATOM   3607 C  CZ  . PHE A 1 477 ? -12.898 -4.058  53.5    1   18.33  ? 469  PHE A CZ  1 
ATOM   3608 N  N   . VAL A 1 478 ? -6.09   -5.76   52.269  1   12.362 ? 470  VAL A N   1 
ATOM   3609 C  CA  . VAL A 1 478 ? -4.751  -5.955  51.697  1   12.779 ? 470  VAL A CA  1 
ATOM   3610 C  C   . VAL A 1 478 ? -4.938  -6.361  50.254  1   12.656 ? 470  VAL A C   1 
ATOM   3611 O  O   . VAL A 1 478 ? -5.765  -7.212  49.914  1   13.598 ? 470  VAL A O   1 
ATOM   3612 C  CB  . VAL A 1 478 ? -3.917  -6.966  52.495  1   12.912 ? 470  VAL A CB  1 
ATOM   3613 C  CG1 . VAL A 1 478 ? -2.606  -7.291  51.763  1   14.058 ? 470  VAL A CG1 1 
ATOM   3614 C  CG2 . VAL A 1 478 ? -3.588  -6.392  53.881  1   16.648 ? 470  VAL A CG2 1 
ATOM   3615 N  N   . LEU A 1 479 ? -4.197  -5.677  49.372  1   11.268 ? 471  LEU A N   1 
ATOM   3616 C  CA  . LEU A 1 479 ? -4.253  -5.954  47.948  1   12.89  ? 471  LEU A CA  1 
ATOM   3617 C  C   . LEU A 1 479 ? -2.862  -6.353  47.465  1   11.287 ? 471  LEU A C   1 
ATOM   3618 O  O   . LEU A 1 479 ? -1.857  -5.867  47.987  1   11.881 ? 471  LEU A O   1 
ATOM   3619 C  CB  . LEU A 1 479 ? -4.649  -4.697  47.16   1   11.87  ? 471  LEU A CB  1 
ATOM   3620 C  CG  . LEU A 1 479 ? -6.094  -4.197  47.383  1   12.068 ? 471  LEU A CG  1 
ATOM   3621 C  CD1 . LEU A 1 479 ? -6.178  -3.342  48.639  1   19.266 ? 471  LEU A CD1 1 
ATOM   3622 C  CD2 . LEU A 1 479 ? -6.566  -3.359  46.195  1   15.862 ? 471  LEU A CD2 1 
ATOM   3623 N  N   . ALA A 1 480 ? -2.82   -7.261  46.493  1   11.939 ? 472  ALA A N   1 
ATOM   3624 C  CA  . ALA A 1 480 ? -1.531  -7.616  45.906  1   11.411 ? 472  ALA A CA  1 
ATOM   3625 C  C   . ALA A 1 480 ? -1.747  -8.242  44.539  1   12.132 ? 472  ALA A C   1 
ATOM   3626 O  O   . ALA A 1 480 ? -2.828  -8.804  44.274  1   12.796 ? 472  ALA A O   1 
ATOM   3627 C  CB  . ALA A 1 480 ? -0.793  -8.627  46.848  1   12.686 ? 472  ALA A CB  1 
ATOM   3628 N  N   . ILE A 1 481 ? -0.736  -8.159  43.689  1   11.69  ? 473  ILE A N   1 
ATOM   3629 C  CA  . ILE A 1 481 ? -0.795  -8.816  42.371  1   11.581 ? 473  ILE A CA  1 
ATOM   3630 C  C   . ILE A 1 481 ? -0.389  -10.289 42.468  1   12.206 ? 473  ILE A C   1 
ATOM   3631 O  O   . ILE A 1 481 ? 0.644   -10.622 43.058  1   13.467 ? 473  ILE A O   1 
ATOM   3632 C  CB  . ILE A 1 481 ? 0.097   -8.095  41.336  1   12.346 ? 473  ILE A CB  1 
ATOM   3633 C  CG1 . ILE A 1 481 ? -0.147  -6.59   41.257  1   14.293 ? 473  ILE A CG1 1 
ATOM   3634 C  CG2 . ILE A 1 481 ? 0.014   -8.745  39.95   1   14.504 ? 473  ILE A CG2 1 
ATOM   3635 C  CD1 . ILE A 1 481 ? -1.56   -6.143  40.921  1   17.67  ? 473  ILE A CD1 1 
ATOM   3636 N  N   . VAL A 1 482 ? -1.241  -11.16  41.926  1   12.898 ? 474  VAL A N   1 
ATOM   3637 C  CA  . VAL A 1 482 ? -0.971  -12.594 41.841  1   13.793 ? 474  VAL A CA  1 
ATOM   3638 C  C   . VAL A 1 482 ? -0.684  -12.97  40.398  1   13.761 ? 474  VAL A C   1 
ATOM   3639 O  O   . VAL A 1 482 ? -1.442  -12.598 39.48   1   14.126 ? 474  VAL A O   1 
ATOM   3640 C  CB  . VAL A 1 482 ? -2.184  -13.393 42.373  1   14.209 ? 474  VAL A CB  1 
ATOM   3641 C  CG1 . VAL A 1 482 ? -2.036  -14.906 42.092  1   17.955 ? 474  VAL A CG1 1 
ATOM   3642 C  CG2 . VAL A 1 482 ? -2.39   -13.12  43.847  1   15.971 ? 474  VAL A CG2 1 
ATOM   3643 N  N   . ASP A 1 483 ? 0.441   -13.668 40.194  1   14.655 ? 475  ASP A N   1 
ATOM   3644 C  CA  . ASP A 1 483 ? 0.769   -14.273 38.895  1   14.514 ? 475  ASP A CA  1 
ATOM   3645 C  C   . ASP A 1 483 ? 0.157   -15.668 38.844  1   17.124 ? 475  ASP A C   1 
ATOM   3646 O  O   . ASP A 1 483 ? 0.563   -16.53  39.645  1   17.243 ? 475  ASP A O   1 
ATOM   3647 C  CB  . ASP A 1 483 ? 2.282   -14.445 38.75   1   19.239 ? 475  ASP A CB  1 
ATOM   3648 C  CG  . ASP A 1 483 ? 3.055   -13.162 38.943  1   23.481 ? 475  ASP A CG  1 
ATOM   3649 O  OD1 . ASP A 1 483 ? 3.322   -12.831 40.119  1   23.15  ? 475  ASP A OD1 1 
ATOM   3650 O  OD2 . ASP A 1 483 ? 3.365   -12.513 37.912  1   22.813 ? 475  ASP A OD2 1 
ATOM   3651 N  N   . ARG A 1 484 ? -0.857  -15.854 37.975  1   17.742 ? 476  ARG A N   1 
ATOM   3652 C  CA  . ARG A 1 484 ? -1.448  -17.174 37.759  1   17.893 ? 476  ARG A CA  1 
ATOM   3653 C  C   . ARG A 1 484 ? -0.607  -17.868 36.693  1   20.862 ? 476  ARG A C   1 
ATOM   3654 O  O   . ARG A 1 484 ? -0.899  -17.71  35.499  1   20.313 ? 476  ARG A O   1 
ATOM   3655 C  CB  . ARG A 1 484 ? -2.903  -16.966 37.327  1   18.461 ? 476  ARG A CB  1 
ATOM   3656 C  CG  . ARG A 1 484 ? -3.856  -16.335 38.326  1   18.763 ? 476  ARG A CG  1 
ATOM   3657 C  CD  . ARG A 1 484 ? -3.932  -17.104 39.676  1   19.606 ? 476  ARG A CD  1 
ATOM   3658 N  NE  . ARG A 1 484 ? -4.504  -18.449 39.48   1   20.7   ? 476  ARG A NE  1 
ATOM   3659 C  CZ  . ARG A 1 484 ? -5.818  -18.678 39.43   1   21.349 ? 476  ARG A CZ  1 
ATOM   3660 N  NH1 . ARG A 1 484 ? -6.727  -17.753 39.704  1   19.03  ? 476  ARG A NH1 1 
ATOM   3661 N  NH2 . ARG A 1 484 ? -6.244  -19.927 39.19   1   20.254 ? 476  ARG A NH2 1 
ATOM   3662 N  N   . LEU A 1 485 ? 0.493   -18.499 37.104  1   19.73  ? 477  LEU A N   1 
ATOM   3663 C  CA  . LEU A 1 485 ? 1.541   -18.904 36.176  1   23.431 ? 477  LEU A CA  1 
ATOM   3664 C  C   . LEU A 1 485 ? 1.077   -19.91  35.126  1   26.837 ? 477  LEU A C   1 
ATOM   3665 O  O   . LEU A 1 485 ? 1.562   -19.843 34.011  1   32.217 ? 477  LEU A O   1 
ATOM   3666 C  CB  . LEU A 1 485 ? 2.78    -19.421 36.908  1   23.57  ? 477  LEU A CB  1 
ATOM   3667 C  CG  . LEU A 1 485 ? 3.464   -18.388 37.82   1   24.331 ? 477  LEU A CG  1 
ATOM   3668 C  CD1 . LEU A 1 485 ? 4.456   -19.103 38.743  1   27.242 ? 477  LEU A CD1 1 
ATOM   3669 C  CD2 . LEU A 1 485 ? 4.159   -17.304 37.009  1   26.999 ? 477  LEU A CD2 1 
ATOM   3670 N  N   . ASP A 1 486 ? 0.149   -20.788 35.476  1   26.037 ? 478  ASP A N   1 
ATOM   3671 C  CA  . ASP A 1 486 ? -0.359  -21.761 34.51   1   31.866 ? 478  ASP A CA  1 
ATOM   3672 C  C   . ASP A 1 486 ? -1.385  -21.147 33.549  1   35.807 ? 478  ASP A C   1 
ATOM   3673 O  O   . ASP A 1 486 ? -1.738  -21.783 32.542  1   32.888 ? 478  ASP A O   1 
ATOM   3674 C  CB  . ASP A 1 486 ? -0.908  -22.997 35.2    1   36.354 ? 478  ASP A CB  1 
ATOM   3675 C  CG  . ASP A 1 486 ? -1.906  -22.761 36.325  1   47.224 ? 478  ASP A CG  1 
ATOM   3676 O  OD1 . ASP A 1 486 ? -2.158  -21.583 36.657  1   46.501 ? 478  ASP A OD1 1 
ATOM   3677 O  OD2 . ASP A 1 486 ? -2.403  -23.765 36.885  1   56.737 ? 478  ASP A OD2 1 
ATOM   3678 N  N   . LEU A 1 487 ? -1.844  -19.909 33.831  1   29.608 ? 479  LEU A N   1 
ATOM   3679 C  CA  . LEU A 1 487 ? -2.895  -19.293 33.018  1   25.464 ? 479  LEU A CA  1 
ATOM   3680 C  C   . LEU A 1 487 ? -2.395  -18.123 32.16   1   24.997 ? 479  LEU A C   1 
ATOM   3681 O  O   . LEU A 1 487 ? -3.201  -17.584 31.411  1   23.097 ? 479  LEU A O   1 
ATOM   3682 C  CB  . LEU A 1 487 ? -4.105  -18.932 33.881  1   25.301 ? 479  LEU A CB  1 
ATOM   3683 C  CG  . LEU A 1 487 ? -4.732  -20.038 34.73   1   27.963 ? 479  LEU A CG  1 
ATOM   3684 C  CD1 . LEU A 1 487 ? -5.829  -19.516 35.604  1   27.289 ? 479  LEU A CD1 1 
ATOM   3685 C  CD2 . LEU A 1 487 ? -5.255  -21.241 33.906  1   30.634 ? 479  LEU A CD2 1 
ATOM   3686 N  N   . ASN A 1 488 ? -1.11   -17.733 32.241  1   22.5   ? 480  ASN A N   1 
ATOM   3687 C  CA  . ASN A 1 488 ? -0.548  -16.566 31.565  1   22.595 ? 480  ASN A CA  1 
ATOM   3688 C  C   . ASN A 1 488 ? -1.493  -15.39  31.839  1   18.708 ? 480  ASN A C   1 
ATOM   3689 O  O   . ASN A 1 488 ? -1.85   -14.643 30.944  1   19.925 ? 480  ASN A O   1 
ATOM   3690 C  CB  . ASN A 1 488 ? -0.297  -16.758 30.052  1   27.601 ? 480  ASN A CB  1 
ATOM   3691 C  CG  . ASN A 1 488 ? 0.509   -15.641 29.365  1   32.885 ? 480  ASN A CG  1 
ATOM   3692 O  OD1 . ASN A 1 488 ? 1.478   -15.112 29.928  1   34.286 ? 480  ASN A OD1 1 
ATOM   3693 N  ND2 . ASN A 1 488 ? 0.178   -15.241 28.136  1   30.491 ? 480  ASN A ND2 1 
ATOM   3694 N  N   . ARG A 1 489 ? -1.817  -15.186 33.13   1   17.603 ? 481  ARG A N   1 
ATOM   3695 C  CA  . ARG A 1 489 ? -2.547  -13.968 33.494  1   17.177 ? 481  ARG A CA  1 
ATOM   3696 C  C   . ARG A 1 489 ? -2.137  -13.487 34.888  1   15.56  ? 481  ARG A C   1 
ATOM   3697 O  O   . ARG A 1 489 ? -1.605  -14.262 35.694  1   16.841 ? 481  ARG A O   1 
ATOM   3698 C  CB  . ARG A 1 489 ? -4.066  -14.121 33.362  1   18.627 ? 481  ARG A CB  1 
ATOM   3699 C  CG  . ARG A 1 489 ? -4.703  -14.963 34.451  1   21.591 ? 481  ARG A CG  1 
ATOM   3700 C  CD  . ARG A 1 489 ? -6.221  -14.64  34.351  1   29.417 ? 481  ARG A CD  1 
ATOM   3701 N  NE  . ARG A 1 489 ? -6.987  -15.292 35.424  1   33.216 ? 481  ARG A NE  1 
ATOM   3702 C  CZ  . ARG A 1 489 ? -7.778  -16.341 35.267  1   34.73  ? 481  ARG A CZ  1 
ATOM   3703 N  NH1 . ARG A 1 489 ? -7.97   -16.895 34.076  1   33.287 ? 481  ARG A NH1 1 
ATOM   3704 N  NH2 . ARG A 1 489 ? -8.365  -16.853 36.333  1   30.799 ? 481  ARG A NH2 1 
ATOM   3705 N  N   . SER A 1 490 ? -2.464  -12.224 35.185  1   12.985 ? 482  SER A N   1 
ATOM   3706 C  CA  . SER A 1 490 ? -2.228  -11.58  36.467  1   12.986 ? 482  SER A CA  1 
ATOM   3707 C  C   . SER A 1 490 ? -3.565  -11.12  37.009  1   13.013 ? 482  SER A C   1 
ATOM   3708 O  O   . SER A 1 490 ? -4.468  -10.794 36.216  1   14.089 ? 482  SER A O   1 
ATOM   3709 C  CB  . SER A 1 490 ? -1.29   -10.374 36.345  1   14.459 ? 482  SER A CB  1 
ATOM   3710 O  OG  . SER A 1 490 ? -0.032  -10.766 35.816  1   14.647 ? 482  SER A OG  1 
ATOM   3711 N  N   . GLU A 1 491 ? -3.666  -11.118 38.342  1   12.987 ? 483  GLU A N   1 
ATOM   3712 C  CA  . GLU A 1 491 ? -4.894  -10.724 39.013  1   13.284 ? 483  GLU A CA  1 
ATOM   3713 C  C   . GLU A 1 491 ? -4.529  -9.874  40.219  1   12.832 ? 483  GLU A C   1 
ATOM   3714 O  O   . GLU A 1 491 ? -3.427  -9.944  40.717  1   15.336 ? 483  GLU A O   1 
ATOM   3715 C  CB  . GLU A 1 491 ? -5.725  -11.928 39.486  1   16.519 ? 483  GLU A CB  1 
ATOM   3716 C  CG  . GLU A 1 491 ? -6.011  -12.994 38.44   1   24.279 ? 483  GLU A CG  1 
ATOM   3717 C  CD  . GLU A 1 491 ? -6.791  -14.159 39.011  1   19.091 ? 483  GLU A CD  1 
ATOM   3718 O  OE1 . GLU A 1 491 ? -6.551  -14.63  40.15   1   22.029 ? 483  GLU A OE1 1 
ATOM   3719 O  OE2 . GLU A 1 491 ? -7.503  -14.644 38.093  1   24.654 ? 483  GLU A OE2 1 
ATOM   3720 N  N   . VAL A 1 492 ? -5.437  -9.037  40.707  1   12.867 ? 484  VAL A N   1 
ATOM   3721 C  CA  . VAL A 1 492 ? -5.281  -8.365  41.995  1   12.059 ? 484  VAL A CA  1 
ATOM   3722 C  C   . VAL A 1 492 ? -6.127  -9.129  42.992  1   13.338 ? 484  VAL A C   1 
ATOM   3723 O  O   . VAL A 1 492 ? -7.339  -9.219  42.776  1   15.118 ? 484  VAL A O   1 
ATOM   3724 C  CB  . VAL A 1 492 ? -5.747  -6.896  41.977  1   13.222 ? 484  VAL A CB  1 
ATOM   3725 C  CG1 . VAL A 1 492 ? -5.389  -6.191  43.289  1   14.834 ? 484  VAL A CG1 1 
ATOM   3726 C  CG2 . VAL A 1 492 ? -5.179  -6.159  40.762  1   16.136 ? 484  VAL A CG2 1 
ATOM   3727 N  N   . VAL A 1 493 ? -5.542  -9.61   44.086  1   12.672 ? 485  VAL A N   1 
ATOM   3728 C  CA  . VAL A 1 493 ? -6.404  -10.184 45.115  1   12.22  ? 485  VAL A CA  1 
ATOM   3729 C  C   . VAL A 1 493 ? -6.721  -9.139  46.177  1   13.783 ? 485  VAL A C   1 
ATOM   3730 O  O   . VAL A 1 493 ? -5.905  -8.233  46.417  1   14.054 ? 485  VAL A O   1 
ATOM   3731 C  CB  . VAL A 1 493 ? -5.815  -11.425 45.788  1   14.943 ? 485  VAL A CB  1 
ATOM   3732 C  CG1 . VAL A 1 493 ? -5.757  -12.566 44.789  1   21.225 ? 485  VAL A CG1 1 
ATOM   3733 C  CG2 . VAL A 1 493 ? -4.481  -11.186 46.529  1   14.848 ? 485  VAL A CG2 1 
ATOM   3734 N  N   . VAL A 1 494 ? -7.892  -9.269  46.828  1   12.76  ? 486  VAL A N   1 
ATOM   3735 C  CA  . VAL A 1 494 ? -8.282  -8.336  47.871  1   13.277 ? 486  VAL A CA  1 
ATOM   3736 C  C   . VAL A 1 494 ? -8.61   -9.215  49.079  1   14.257 ? 486  VAL A C   1 
ATOM   3737 O  O   . VAL A 1 494 ? -9.478  -10.088 48.966  1   14.958 ? 486  VAL A O   1 
ATOM   3738 C  CB  . VAL A 1 494 ? -9.546  -7.524  47.464  1   13.926 ? 486  VAL A CB  1 
ATOM   3739 C  CG1 . VAL A 1 494 ? -9.943  -6.521  48.567  1   15.484 ? 486  VAL A CG1 1 
ATOM   3740 C  CG2 . VAL A 1 494 ? -9.313  -6.776  46.123  1   15.93  ? 486  VAL A CG2 1 
ATOM   3741 N  N   . ILE A 1 495 ? -7.953  -8.921  50.21   1   13.444 ? 487  ILE A N   1 
ATOM   3742 C  CA  . ILE A 1 495 ? -8.099  -9.722  51.439  1   12.391 ? 487  ILE A CA  1 
ATOM   3743 C  C   . ILE A 1 495 ? -8.627  -8.789  52.517  1   14.062 ? 487  ILE A C   1 
ATOM   3744 O  O   . ILE A 1 495 ? -8.083  -7.702  52.707  1   14.489 ? 487  ILE A O   1 
ATOM   3745 C  CB  . ILE A 1 495 ? -6.732  -10.288 51.85   1   13.01  ? 487  ILE A CB  1 
ATOM   3746 C  CG1 . ILE A 1 495 ? -6.244  -11.274 50.795  1   12.945 ? 487  ILE A CG1 1 
ATOM   3747 C  CG2 . ILE A 1 495 ? -6.796  -10.955 53.248  1   15.191 ? 487  ILE A CG2 1 
ATOM   3748 C  CD1 . ILE A 1 495 ? -4.72   -11.369 50.758  1   14.115 ? 487  ILE A CD1 1 
ATOM   3749 N  N   . ASP A 1 496 ? -9.652  -9.208  53.285  1   13.764 ? 488  ASP A N   1 
ATOM   3750 C  CA  . ASP A 1 496 ? -10.064 -8.487  54.488  1   14.871 ? 488  ASP A CA  1 
ATOM   3751 C  C   . ASP A 1 496 ? -9.267  -9.038  55.676  1   15.788 ? 488  ASP A C   1 
ATOM   3752 O  O   . ASP A 1 496 ? -9.205  -10.256 55.871  1   15.938 ? 488  ASP A O   1 
ATOM   3753 C  CB  . ASP A 1 496 ? -11.556 -8.743  54.712  1   15.093 ? 488  ASP A CB  1 
ATOM   3754 C  CG  . ASP A 1 496 ? -12.182 -7.883  55.808  1   16.995 ? 488  ASP A CG  1 
ATOM   3755 O  OD1 . ASP A 1 496 ? -11.555 -7.733  56.856  1   17.405 ? 488  ASP A OD1 1 
ATOM   3756 O  OD2 . ASP A 1 496 ? -13.299 -7.348  55.582  1   18.662 ? 488  ASP A OD2 1 
ATOM   3757 N  N   . THR A 1 497 ? -8.618  -8.141  56.421  1   14.88  ? 489  THR A N   1 
ATOM   3758 C  CA  . THR A 1 497 ? -7.769  -8.535  57.544  1   15.652 ? 489  THR A CA  1 
ATOM   3759 C  C   . THR A 1 497 ? -8.534  -9.303  58.633  1   15.692 ? 489  THR A C   1 
ATOM   3760 O  O   . THR A 1 497 ? -7.881  -9.926  59.477  1   17.105 ? 489  THR A O   1 
ATOM   3761 C  CB  . THR A 1 497 ? -7.044  -7.314  58.139  1   16.274 ? 489  THR A CB  1 
ATOM   3762 O  OG1 . THR A 1 497 ? -8.023  -6.365  58.585  1   17.615 ? 489  THR A OG1 1 
ATOM   3763 C  CG2 . THR A 1 497 ? -6.124  -6.68   57.093  1   16.652 ? 489  THR A CG2 1 
ATOM   3764 N  N   . ARG A 1 498 ? -9.87   -9.261  58.586  1   17.214 ? 490  ARG A N   1 
ATOM   3765 C  CA  . ARG A 1 498 ? -10.621 -10.018 59.594  1   18.827 ? 490  ARG A CA  1 
ATOM   3766 C  C   . ARG A 1 498 ? -10.508 -11.512 59.311  1   22.385 ? 490  ARG A C   1 
ATOM   3767 O  O   . ARG A 1 498 ? -10.761 -12.331 60.205  1   23.131 ? 490  ARG A O   1 
ATOM   3768 C  CB  . ARG A 1 498 ? -12.107 -9.661  59.529  1   21.326 ? 490  ARG A CB  1 
ATOM   3769 C  CG  . ARG A 1 498 ? -12.374 -8.292  60.125  1   23.298 ? 490  ARG A CG  1 
ATOM   3770 C  CD  . ARG A 1 498 ? -13.821 -7.833  60.044  1   28.704 ? 490  ARG A CD  1 
ATOM   3771 N  NE  . ARG A 1 498 ? -14.26  -7.667  58.658  1   41.785 ? 490  ARG A NE  1 
ATOM   3772 C  CZ  . ARG A 1 498 ? -15.517 -7.618  58.233  1   43.815 ? 490  ARG A CZ  1 
ATOM   3773 N  NH1 . ARG A 1 498 ? -16.504 -7.42   59.103  1   36.005 ? 490  ARG A NH1 1 
ATOM   3774 N  NH2 . ARG A 1 498 ? -15.752 -7.746  56.933  1   34.028 ? 490  ARG A NH2 1 
ATOM   3775 N  N   . ASP A 1 499 ? -10.146 -11.907 58.087  1   18.434 ? 491  ASP A N   1 
ATOM   3776 C  CA  . ASP A 1 499 ? -9.725  -13.26  57.802  1   20.262 ? 491  ASP A CA  1 
ATOM   3777 C  C   . ASP A 1 499 ? -8.628  -13.21  56.736  1   17.001 ? 491  ASP A C   1 
ATOM   3778 O  O   . ASP A 1 499 ? -8.907  -13.331 55.54   1   18.536 ? 491  ASP A O   1 
ATOM   3779 C  CB  . ASP A 1 499 ? -10.838 -14.195 57.346  1   22.32  ? 491  ASP A CB  1 
ATOM   3780 C  CG  . ASP A 1 499 ? -10.418 -15.654 57.117  1   23.347 ? 491  ASP A CG  1 
ATOM   3781 O  OD1 . ASP A 1 499 ? -9.208  -16.026 57.3    1   24.885 ? 491  ASP A OD1 1 
ATOM   3782 O  OD2 . ASP A 1 499 ? -11.275 -16.43  56.666  1   26.93  ? 491  ASP A OD2 1 
ATOM   3783 N  N   . PHE A 1 500 ? -7.394  -13.18  57.216  1   18.465 ? 492  PHE A N   1 
ATOM   3784 C  CA  . PHE A 1 500 ? -6.255  -12.963 56.335  1   16.242 ? 492  PHE A CA  1 
ATOM   3785 C  C   . PHE A 1 500 ? -6.032  -14.131 55.373  1   18.444 ? 492  PHE A C   1 
ATOM   3786 O  O   . PHE A 1 500 ? -5.339  -13.979 54.363  1   17.919 ? 492  PHE A O   1 
ATOM   3787 C  CB  . PHE A 1 500 ? -5.021  -12.622 57.167  1   16.087 ? 492  PHE A CB  1 
ATOM   3788 C  CG  . PHE A 1 500 ? -3.913  -11.986 56.325  1   17.168 ? 492  PHE A CG  1 
ATOM   3789 C  CD1 . PHE A 1 500 ? -4.078  -10.679 55.843  1   16.283 ? 492  PHE A CD1 1 
ATOM   3790 C  CD2 . PHE A 1 500 ? -2.738  -12.684 56.034  1   16.577 ? 492  PHE A CD2 1 
ATOM   3791 C  CE1 . PHE A 1 500 ? -3.07   -10.101 55.063  1   15.765 ? 492  PHE A CE1 1 
ATOM   3792 C  CE2 . PHE A 1 500 ? -1.748  -12.121 55.244  1   15.996 ? 492  PHE A CE2 1 
ATOM   3793 C  CZ  . PHE A 1 500 ? -1.888  -10.816 54.814  1   16.763 ? 492  PHE A CZ  1 
ATOM   3794 N  N   . THR A 1 501 ? -6.572  -15.321 55.722  1   17.217 ? 493  THR A N   1 
ATOM   3795 C  CA  . THR A 1 501 ? -6.338  -16.515 54.931  1   16.46  ? 493  THR A CA  1 
ATOM   3796 C  C   . THR A 1 501 ? -7.175  -16.56  53.65   1   15.721 ? 493  THR A C   1 
ATOM   3797 O  O   . THR A 1 501 ? -6.938  -17.441 52.819  1   18.171 ? 493  THR A O   1 
ATOM   3798 C  CB  . THR A 1 501 ? -6.523  -17.8   55.763  1   18.369 ? 493  THR A CB  1 
ATOM   3799 O  OG1 . THR A 1 501 ? -7.942  -17.993 55.872  1   19.765 ? 493  THR A OG1 1 
ATOM   3800 C  CG2 . THR A 1 501 ? -5.8    -17.777 57.092  1   18     ? 493  THR A CG2 1 
ATOM   3801 N  N   . LYS A 1 502 ? -8.178  -15.677 53.521  1   16.73  ? 494  LYS A N   1 
ATOM   3802 C  CA  . LYS A 1 502 ? -9.13   -15.783 52.403  1   17.506 ? 494  LYS A CA  1 
ATOM   3803 C  C   . LYS A 1 502 ? -9.215  -14.486 51.585  1   17.245 ? 494  LYS A C   1 
ATOM   3804 O  O   . LYS A 1 502 ? -9.3    -13.404 52.159  1   17.927 ? 494  LYS A O   1 
ATOM   3805 C  CB  . LYS A 1 502 ? -10.476 -16.132 53.061  1   22.693 ? 494  LYS A CB  1 
ATOM   3806 C  CG  . LYS A 1 502 ? -11.674 -16.37  52.161  1   30.666 ? 494  LYS A CG  1 
ATOM   3807 C  CD  . LYS A 1 502 ? -12.814 -16.802 53.095  1   41.074 ? 494  LYS A CD  1 
ATOM   3808 C  CE  . LYS A 1 502 ? -13.996 -17.514 52.505  1   50.186 ? 494  LYS A CE  1 
ATOM   3809 N  NZ  . LYS A 1 502 ? -14.621 -16.896 51.331  1   52.307 ? 494  LYS A NZ  1 
ATOM   3810 N  N   . ALA A 1 503 ? -9.203  -14.634 50.263  1   16.131 ? 495  ALA A N   1 
ATOM   3811 C  CA  . ALA A 1 503 ? -9.532  -13.508 49.39   1   16.238 ? 495  ALA A CA  1 
ATOM   3812 C  C   . ALA A 1 503 ? -11.036 -13.275 49.378  1   17.448 ? 495  ALA A C   1 
ATOM   3813 O  O   . ALA A 1 503 ? -11.821 -14.253 49.244  1   20.057 ? 495  ALA A O   1 
ATOM   3814 C  CB  . ALA A 1 503 ? -9.045  -13.78  47.988  1   19.036 ? 495  ALA A CB  1 
ATOM   3815 N  N   . VAL A 1 504 ? -11.459 -11.994 49.469  1   14.981 ? 496  VAL A N   1 
ATOM   3816 C  CA  . VAL A 1 504 ? -12.872 -11.663 49.275  1   15.314 ? 496  VAL A CA  1 
ATOM   3817 C  C   . VAL A 1 504 ? -13.172 -11.36  47.802  1   15.407 ? 496  VAL A C   1 
ATOM   3818 O  O   . VAL A 1 504 ? -14.336 -11.335 47.405  1   17.432 ? 496  VAL A O   1 
ATOM   3819 C  CB  . VAL A 1 504 ? -13.352 -10.504 50.172  1   14.92  ? 496  VAL A CB  1 
ATOM   3820 C  CG1 . VAL A 1 504 ? -13.213 -10.864 51.653  1   20.801 ? 496  VAL A CG1 1 
ATOM   3821 C  CG2 . VAL A 1 504 ? -12.645 -9.148  49.919  1   18.126 ? 496  VAL A CG2 1 
ATOM   3822 N  N   . ALA A 1 505 ? -12.152 -10.968 47.018  1   15.454 ? 497  ALA A N   1 
ATOM   3823 C  CA  . ALA A 1 505 ? -12.381 -10.594 45.639  1   15.45  ? 497  ALA A CA  1 
ATOM   3824 C  C   . ALA A 1 505 ? -11.091 -10.789 44.867  1   13.314 ? 497  ALA A C   1 
ATOM   3825 O  O   . ALA A 1 505 ? -10.003 -10.815 45.45   1   14.189 ? 497  ALA A O   1 
ATOM   3826 C  CB  . ALA A 1 505 ? -12.834 -9.144  45.504  1   16.195 ? 497  ALA A CB  1 
ATOM   3827 N  N   . ALA A 1 506 ? -11.25  -10.922 43.54   1   15.507 ? 498  ALA A N   1 
ATOM   3828 C  CA  . ALA A 1 506 ? -10.115 -10.928 42.625  1   14.523 ? 498  ALA A CA  1 
ATOM   3829 C  C   . ALA A 1 506 ? -10.473 -10.031 41.471  1   16.935 ? 498  ALA A C   1 
ATOM   3830 O  O   . ALA A 1 506 ? -11.592 -10.124 40.978  1   18.155 ? 498  ALA A O   1 
ATOM   3831 C  CB  . ALA A 1 506 ? -9.752  -12.322 42.125  1   17.155 ? 498  ALA A CB  1 
ATOM   3832 N  N   . VAL A 1 507 ? -9.525  -9.2    41.062  1   13.665 ? 499  VAL A N   1 
ATOM   3833 C  CA  . VAL A 1 507 ? -9.647  -8.41   39.849  1   12.754 ? 499  VAL A CA  1 
ATOM   3834 C  C   . VAL A 1 507 ? -8.902  -9.159  38.757  1   13.447 ? 499  VAL A C   1 
ATOM   3835 O  O   . VAL A 1 507 ? -7.695  -9.396  38.901  1   16.2   ? 499  VAL A O   1 
ATOM   3836 C  CB  . VAL A 1 507 ? -9.024  -7.031  40.107  1   12.861 ? 499  VAL A CB  1 
ATOM   3837 C  CG1 . VAL A 1 507 ? -9.052  -6.197  38.794  1   14.462 ? 499  VAL A CG1 1 
ATOM   3838 C  CG2 . VAL A 1 507 ? -9.731  -6.313  41.248  1   14.823 ? 499  VAL A CG2 1 
ATOM   3839 N  N   . GLN A 1 508 ? -9.609  -9.593  37.719  1   13.032 ? 500  GLN A N   1 
ATOM   3840 C  CA  . GLN A 1 508 ? -9.031  -10.557 36.78   1   12.617 ? 500  GLN A CA  1 
ATOM   3841 C  C   . GLN A 1 508 ? -8.696  -9.822  35.477  1   12.471 ? 500  GLN A C   1 
ATOM   3842 O  O   . GLN A 1 508 ? -9.586  -9.548  34.653  1   13.566 ? 500  GLN A O   1 
ATOM   3843 C  CB  . GLN A 1 508 ? -10.094 -11.638 36.537  1   16.269 ? 500  GLN A CB  1 
ATOM   3844 C  CG  . GLN A 1 508 ? -9.689  -12.769 35.605  1   19.955 ? 500  GLN A CG  1 
ATOM   3845 C  CD  . GLN A 1 508 ? -10.795 -13.793 35.383  1   25.865 ? 500  GLN A CD  1 
ATOM   3846 O  OE1 . GLN A 1 508 ? -11.657 -14.01  36.262  1   21.613 ? 500  GLN A OE1 1 
ATOM   3847 N  NE2 . GLN A 1 508 ? -10.721 -14.455 34.224  1   28.118 ? 500  GLN A NE2 1 
ATOM   3848 N  N   . LEU A 1 509 ? -7.407  -9.565  35.245  1   13.051 ? 501  LEU A N   1 
ATOM   3849 C  CA  . LEU A 1 509 ? -7.012  -9.068  33.93   1   13.374 ? 501  LEU A CA  1 
ATOM   3850 C  C   . LEU A 1 509 ? -7.124  -10.205 32.915  1   15.338 ? 501  LEU A C   1 
ATOM   3851 O  O   . LEU A 1 509 ? -7.074  -11.381 33.294  1   15.677 ? 501  LEU A O   1 
ATOM   3852 C  CB  . LEU A 1 509 ? -5.57   -8.544  33.937  1   13.055 ? 501  LEU A CB  1 
ATOM   3853 C  CG  . LEU A 1 509 ? -5.357  -7.276  34.775  1   12.965 ? 501  LEU A CG  1 
ATOM   3854 C  CD1 . LEU A 1 509 ? -3.86   -6.982  34.886  1   14.473 ? 501  LEU A CD1 1 
ATOM   3855 C  CD2 . LEU A 1 509 ? -5.989  -6.07   34.06   1   14.637 ? 501  LEU A CD2 1 
ATOM   3856 N  N   . PRO A 1 510 ? -7.27   -9.864  31.618  1   14.206 ? 502  PRO A N   1 
ATOM   3857 C  CA  . PRO A 1 510 ? -7.293  -10.838 30.546  1   14.911 ? 502  PRO A CA  1 
ATOM   3858 C  C   . PRO A 1 510 ? -5.907  -11.253 30.035  1   16.239 ? 502  PRO A C   1 
ATOM   3859 O  O   . PRO A 1 510 ? -5.792  -11.927 29.012  1   18.197 ? 502  PRO A O   1 
ATOM   3860 C  CB  . PRO A 1 510 ? -8.08   -10.095 29.472  1   15.076 ? 502  PRO A CB  1 
ATOM   3861 C  CG  . PRO A 1 510 ? -7.688  -8.686  29.619  1   16.542 ? 502  PRO A CG  1 
ATOM   3862 C  CD  . PRO A 1 510 ? -7.513  -8.491  31.14   1   15.424 ? 502  PRO A CD  1 
ATOM   3863 N  N   . PHE A 1 511 ? -4.868  -10.854 30.783  1   15.052 ? 503  PHE A N   1 
ATOM   3864 C  CA  . PHE A 1 511 ? -3.465  -11.075 30.39   1   14.157 ? 503  PHE A CA  1 
ATOM   3865 C  C   . PHE A 1 511 ? -2.613  -10.971 31.631  1   14.776 ? 503  PHE A C   1 
ATOM   3866 O  O   . PHE A 1 511 ? -3.124  -10.624 32.71   1   13.942 ? 503  PHE A O   1 
ATOM   3867 C  CB  . PHE A 1 511 ? -3.062  -10.066 29.301  1   14.576 ? 503  PHE A CB  1 
ATOM   3868 C  CG  . PHE A 1 511 ? -3.404  -8.599  29.509  1   13.628 ? 503  PHE A CG  1 
ATOM   3869 C  CD1 . PHE A 1 511 ? -3.081  -7.907  30.684  1   14.565 ? 503  PHE A CD1 1 
ATOM   3870 C  CD2 . PHE A 1 511 ? -4.123  -7.925  28.512  1   15.901 ? 503  PHE A CD2 1 
ATOM   3871 C  CE1 . PHE A 1 511 ? -3.333  -6.539  30.842  1   17.044 ? 503  PHE A CE1 1 
ATOM   3872 C  CE2 . PHE A 1 511 ? -4.359  -6.556  28.65   1   17.562 ? 503  PHE A CE2 1 
ATOM   3873 C  CZ  . PHE A 1 511 ? -3.997  -5.856  29.806  1   17.743 ? 503  PHE A CZ  1 
ATOM   3874 N  N   . ALA A 1 512 ? -1.324  -11.273 31.434  1   14.051 ? 504  ALA A N   1 
ATOM   3875 C  CA  . ALA A 1 512 ? -0.316  -11.111 32.485  1   13.869 ? 504  ALA A CA  1 
ATOM   3876 C  C   . ALA A 1 512 ? 0.418   -9.796  32.278  1   13.749 ? 504  ALA A C   1 
ATOM   3877 O  O   . ALA A 1 512 ? 0.575   -9.314  31.149  1   14.973 ? 504  ALA A O   1 
ATOM   3878 C  CB  . ALA A 1 512 ? 0.696   -12.236 32.393  1   14.161 ? 504  ALA A CB  1 
ATOM   3879 N  N   . ILE A 1 513 ? 0.832   -9.199  33.399  1   14.044 ? 505  ILE A N   1 
ATOM   3880 C  CA  . ILE A 1 513 ? 1.707   -8.036  33.4    1   13.39  ? 505  ILE A CA  1 
ATOM   3881 C  C   . ILE A 1 513 ? 3.051   -8.474  33.993  1   12.67  ? 505  ILE A C   1 
ATOM   3882 O  O   . ILE A 1 513 ? 3.176   -9.546  34.6    1   13.152 ? 505  ILE A O   1 
ATOM   3883 C  CB  . ILE A 1 513 ? 1.078   -6.817  34.112  1   14.046 ? 505  ILE A CB  1 
ATOM   3884 C  CG1 . ILE A 1 513 ? 0.851   -7.073  35.629  1   15.056 ? 505  ILE A CG1 1 
ATOM   3885 C  CG2 . ILE A 1 513 ? -0.205  -6.376  33.391  1   16.521 ? 505  ILE A CG2 1 
ATOM   3886 C  CD1 . ILE A 1 513 ? 0.316   -5.873  36.436  1   17.445 ? 505  ILE A CD1 1 
ATOM   3887 N  N   . ARG A 1 514 ? 4.092   -7.63   33.804  1   12.924 ? 506  ARG A N   1 
ATOM   3888 C  CA  . ARG A 1 514 ? 5.367   -7.957  34.431  1   13.005 ? 506  ARG A CA  1 
ATOM   3889 C  C   . ARG A 1 514 ? 5.216   -8.062  35.95   1   13.435 ? 506  ARG A C   1 
ATOM   3890 O  O   . ARG A 1 514 ? 4.376   -7.37   36.574  1   13.523 ? 506  ARG A O   1 
ATOM   3891 C  CB  . ARG A 1 514 ? 6.332   -6.772  34.214  1   14.506 ? 506  ARG A CB  1 
ATOM   3892 C  CG  . ARG A 1 514 ? 7.042   -6.809  32.861  1   16.252 ? 506  ARG A CG  1 
ATOM   3893 C  CD  . ARG A 1 514 ? 8.143   -7.899  32.866  1   19.262 ? 506  ARG A CD  1 
ATOM   3894 N  NE  . ARG A 1 514 ? 8.953   -7.672  31.677  1   20.432 ? 506  ARG A NE  1 
ATOM   3895 C  CZ  . ARG A 1 514 ? 9.979   -8.448  31.365  1   18.044 ? 506  ARG A CZ  1 
ATOM   3896 N  NH1 . ARG A 1 514 ? 10.374  -9.396  32.223  1   19.342 ? 506  ARG A NH1 1 
ATOM   3897 N  NH2 . ARG A 1 514 ? 10.691  -8.21   30.285  1   17.882 ? 506  ARG A NH2 1 
ATOM   3898 N  N   . SER A 1 515 ? 6.079   -8.901  36.569  1   13.627 ? 507  SER A N   1 
ATOM   3899 C  CA  . SER A 1 515 ? 6.205   -8.904  38.006  1   13.969 ? 507  SER A CA  1 
ATOM   3900 C  C   . SER A 1 515 ? 6.991   -7.642  38.377  1   15.357 ? 507  SER A C   1 
ATOM   3901 O  O   . SER A 1 515 ? 8.059   -7.371  37.798  1   15.658 ? 507  SER A O   1 
ATOM   3902 C  CB  . SER A 1 515 ? 6.921   -10.143 38.487  1   16.155 ? 507  SER A CB  1 
ATOM   3903 O  OG  . SER A 1 515 ? 6.908   -10.191 39.919  1   16.054 ? 507  SER A OG  1 
ATOM   3904 N  N   . GLY A 1 516 ? 6.432   -6.824  39.265  1   12.765 ? 508  GLY A N   1 
ATOM   3905 C  CA  . GLY A 1 516 ? 6.967   -5.493  39.509  1   13.378 ? 508  GLY A CA  1 
ATOM   3906 C  C   . GLY A 1 516 ? 7.893   -5.412  40.716  1   13.728 ? 508  GLY A C   1 
ATOM   3907 O  O   . GLY A 1 516 ? 8.397   -6.41   41.237  1   14.477 ? 508  GLY A O   1 
ATOM   3908 N  N   . ILE A 1 517 ? 8.132   -4.173  41.134  1   12.245 ? 509  ILE A N   1 
ATOM   3909 C  CA  . ILE A 1 517 ? 8.971   -3.881  42.281  1   12.607 ? 509  ILE A CA  1 
ATOM   3910 C  C   . ILE A 1 517 ? 8.009   -3.439  43.379  1   12.762 ? 509  ILE A C   1 
ATOM   3911 O  O   . ILE A 1 517 ? 7.501   -4.343  44.069  1   13.38  ? 509  ILE A O   1 
ATOM   3912 C  CB  . ILE A 1 517 ? 10.173  -2.983  41.884  1   13.703 ? 509  ILE A CB  1 
ATOM   3913 C  CG1 . ILE A 1 517 ? 10.931  -3.665  40.72   1   15.967 ? 509  ILE A CG1 1 
ATOM   3914 C  CG2 . ILE A 1 517 ? 11.095  -2.78   43.098  1   15.023 ? 509  ILE A CG2 1 
ATOM   3915 C  CD1 . ILE A 1 517 ? 12.091  -2.866  40.136  1   16.01  ? 509  ILE A CD1 1 
ATOM   3916 N  N   . HIS A 1 518 ? 7.791   -2.134  43.55   1   11.783 ? 510  HIS A N   1 
ATOM   3917 C  CA  . HIS A 1 518 ? 6.865   -1.674  44.563  1   11.679 ? 510  HIS A CA  1 
ATOM   3918 C  C   . HIS A 1 518 ? 5.586   -1.193  43.894  1   13.054 ? 510  HIS A C   1 
ATOM   3919 O  O   . HIS A 1 518 ? 5.484   -0.94   42.681  1   13.74  ? 510  HIS A O   1 
ATOM   3920 C  CB  . HIS A 1 518 ? 7.458   -0.518  45.389  1   12.699 ? 510  HIS A CB  1 
ATOM   3921 C  CG  . HIS A 1 518 ? 8.682   -0.947  46.12   1   12.675 ? 510  HIS A CG  1 
ATOM   3922 N  ND1 . HIS A 1 518 ? 8.663   -1.735  47.255  1   11.927 ? 510  HIS A ND1 1 
ATOM   3923 C  CD2 . HIS A 1 518 ? 9.972   -0.784  45.784  1   12.497 ? 510  HIS A CD2 1 
ATOM   3924 C  CE1 . HIS A 1 518 ? 9.906   -2.022  47.606  1   11.692 ? 510  HIS A CE1 1 
ATOM   3925 N  NE2 . HIS A 1 518 ? 10.748  -1.432  46.739  1   12.264 ? 510  HIS A NE2 1 
ATOM   3926 N  N   . GLY A 1 519 ? 4.587   -1.036  44.755  1   12.025 ? 511  GLY A N   1 
ATOM   3927 C  CA  . GLY A 1 519 ? 3.337   -0.382  44.446  1   13.003 ? 511  GLY A CA  1 
ATOM   3928 C  C   . GLY A 1 519 ? 2.872   0.34    45.706  1   11.781 ? 511  GLY A C   1 
ATOM   3929 O  O   . GLY A 1 519 ? 3.363   0.093   46.816  1   12.489 ? 511  GLY A O   1 
ATOM   3930 N  N   . GLN A 1 520 ? 1.802   1.115   45.535  1   11.876 ? 512  GLN A N   1 
ATOM   3931 C  CA  . GLN A 1 520 ? 1.258   1.815   46.691  1   11.697 ? 512  GLN A CA  1 
ATOM   3932 C  C   . GLN A 1 520 ? -0.244  1.922   46.549  1   11.487 ? 512  GLN A C   1 
ATOM   3933 O  O   . GLN A 1 520 ? -0.794  2.128   45.431  1   11.228 ? 512  GLN A O   1 
ATOM   3934 C  CB  . GLN A 1 520 ? 1.799   3.25    46.784  1   12.646 ? 512  GLN A CB  1 
ATOM   3935 C  CG  . GLN A 1 520 ? 3.325   3.31    46.868  1   12.024 ? 512  GLN A CG  1 
ATOM   3936 C  CD  . GLN A 1 520 ? 3.907   2.755   48.162  1   13.691 ? 512  GLN A CD  1 
ATOM   3937 O  OE1 . GLN A 1 520 ? 3.224   2.761   49.213  1   14.156 ? 512  GLN A OE1 1 
ATOM   3938 N  NE2 . GLN A 1 520 ? 5.169   2.323   48.124  1   14.373 ? 512  GLN A NE2 1 
ATOM   3939 N  N   . TRP A 1 521 ? -0.932  1.783   47.699  1   11.784 ? 513  TRP A N   1 
ATOM   3940 C  CA  . TRP A 1 521 ? -2.328  2.213   47.752  1   11.451 ? 513  TRP A CA  1 
ATOM   3941 C  C   . TRP A 1 521 ? -2.361  3.725   47.947  1   11.769 ? 513  TRP A C   1 
ATOM   3942 O  O   . TRP A 1 521 ? -1.788  4.226   48.917  1   13.329 ? 513  TRP A O   1 
ATOM   3943 C  CB  . TRP A 1 521 ? -3.057  1.557   48.94   1   11.727 ? 513  TRP A CB  1 
ATOM   3944 C  CG  . TRP A 1 521 ? -4.499  1.99    48.953  1   12.969 ? 513  TRP A CG  1 
ATOM   3945 C  CD1 . TRP A 1 521 ? -5.031  2.901   49.839  1   13.378 ? 513  TRP A CD1 1 
ATOM   3946 C  CD2 . TRP A 1 521 ? -5.536  1.638   48.013  1   12.608 ? 513  TRP A CD2 1 
ATOM   3947 N  NE1 . TRP A 1 521 ? -6.336  3.135   49.493  1   13.504 ? 513  TRP A NE1 1 
ATOM   3948 C  CE2 . TRP A 1 521 ? -6.704  2.362   48.416  1   12.38  ? 513  TRP A CE2 1 
ATOM   3949 C  CE3 . TRP A 1 521 ? -5.604  0.761   46.929  1   12.761 ? 513  TRP A CE3 1 
ATOM   3950 C  CZ2 . TRP A 1 521 ? -7.896  2.233   47.691  1   13.535 ? 513  TRP A CZ2 1 
ATOM   3951 C  CZ3 . TRP A 1 521 ? -6.782  0.656   46.23   1   14.321 ? 513  TRP A CZ3 1 
ATOM   3952 C  CH2 . TRP A 1 521 ? -7.925  1.381   46.629  1   14.028 ? 513  TRP A CH2 1 
ATOM   3953 N  N   A ILE A 1 522 ? -3.026  4.418   47.013  0.5 12.091 ? 514  ILE A N   1 
ATOM   3954 N  N   B ILE A 1 522 ? -3.032  4.416   47.017  0.5 12.338 ? 514  ILE A N   1 
ATOM   3955 C  CA  A ILE A 1 522 ? -3.127  5.868   47.105  0.5 12.532 ? 514  ILE A CA  1 
ATOM   3956 C  CA  B ILE A 1 522 ? -3.135  5.865   47.112  0.5 13.056 ? 514  ILE A CA  1 
ATOM   3957 C  C   A ILE A 1 522 ? -4.603  6.191   47.256  0.5 13.408 ? 514  ILE A C   1 
ATOM   3958 C  C   B ILE A 1 522 ? -4.606  6.198   47.251  0.5 13.723 ? 514  ILE A C   1 
ATOM   3959 O  O   A ILE A 1 522 ? -5.358  6.004   46.292  0.5 13.032 ? 514  ILE A O   1 
ATOM   3960 O  O   B ILE A 1 522 ? -5.358  6.014   46.284  0.5 13.321 ? 514  ILE A O   1 
ATOM   3961 C  CB  A ILE A 1 522 ? -2.551  6.573   45.878  0.5 12.548 ? 514  ILE A CB  1 
ATOM   3962 C  CB  B ILE A 1 522 ? -2.498  6.561   45.912  0.5 13.552 ? 514  ILE A CB  1 
ATOM   3963 C  CG1 A ILE A 1 522 ? -1.098  6.141   45.571  0.5 12.569 ? 514  ILE A CG1 1 
ATOM   3964 C  CG1 B ILE A 1 522 ? -1.023  6.184   45.862  0.5 14.147 ? 514  ILE A CG1 1 
ATOM   3965 C  CG2 A ILE A 1 522 ? -2.677  8.089   46.023  0.5 13.868 ? 514  ILE A CG2 1 
ATOM   3966 C  CG2 B ILE A 1 522 ? -2.701  8.074   45.982  0.5 15.133 ? 514  ILE A CG2 1 
ATOM   3967 C  CD1 A ILE A 1 522 ? -0.117  6.492   46.669  0.5 13.079 ? 514  ILE A CD1 1 
ATOM   3968 C  CD1 B ILE A 1 522 ? -0.195  6.874   44.814  0.5 14.946 ? 514  ILE A CD1 1 
ATOM   3969 N  N   . PRO A 1 523 ? -5.046  6.676   48.44   1   13.847 ? 515  PRO A N   1 
ATOM   3970 C  CA  . PRO A 1 523 ? -6.471  6.952   48.653  1   15.084 ? 515  PRO A CA  1 
ATOM   3971 C  C   . PRO A 1 523 ? -6.99   8.022   47.712  1   12.924 ? 515  PRO A C   1 
ATOM   3972 O  O   . PRO A 1 523 ? -6.269  8.958   47.3    1   14.879 ? 515  PRO A O   1 
ATOM   3973 C  CB  . PRO A 1 523 ? -6.468  7.505   50.117  1   16.83  ? 515  PRO A CB  1 
ATOM   3974 C  CG  . PRO A 1 523 ? -5.195  7.105   50.75   1   19.025 ? 515  PRO A CG  1 
ATOM   3975 C  CD  . PRO A 1 523 ? -4.207  6.891   49.648  1   15.74  ? 515  PRO A CD  1 
ATOM   3976 N  N   . GLY A 1 524 ? -8.255  7.9     47.33   1   14.47  ? 516  GLY A N   1 
ATOM   3977 C  CA  . GLY A 1 524 ? -8.84   8.917   46.454  1   15.403 ? 516  GLY A CA  1 
ATOM   3978 C  C   . GLY A 1 524 ? -8.823  10.305  47.113  1   16.454 ? 516  GLY A C   1 
ATOM   3979 O  O   . GLY A 1 524 ? -8.633  11.305  46.398  1   15.43  ? 516  GLY A O   1 
ATOM   3980 N  N   . GLU A 1 525 ? -8.89   10.315  48.457  1   16.402 ? 517  GLU A N   1 
ATOM   3981 C  CA  . GLU A 1 525 ? -8.919  11.563  49.214  1   16.824 ? 517  GLU A CA  1 
ATOM   3982 C  C   . GLU A 1 525 ? -7.722  12.448  48.879  1   18.385 ? 517  GLU A C   1 
ATOM   3983 O  O   . GLU A 1 525 ? -7.886  13.654  48.842  1   19.855 ? 517  GLU A O   1 
ATOM   3984 C  CB  . GLU A 1 525 ? -8.874  11.096  50.668  1   22.765 ? 517  GLU A CB  1 
ATOM   3985 C  CG  . GLU A 1 525 ? -8.837  12.205  51.715  1   32.285 ? 517  GLU A CG  1 
ATOM   3986 C  CD  . GLU A 1 525 ? -8.392  11.718  53.086  1   41.471 ? 517  GLU A CD  1 
ATOM   3987 O  OE1 . GLU A 1 525 ? -7.878  10.563  53.276  1   42.761 ? 517  GLU A OE1 1 
ATOM   3988 O  OE2 . GLU A 1 525 ? -8.549  12.583  53.99   1   47.269 ? 517  GLU A OE2 1 
ATOM   3989 N  N   . VAL A 1 526 ? -6.533  11.873  48.607  1   14.697 ? 518  VAL A N   1 
ATOM   3990 C  CA  . VAL A 1 526 ? -5.29   12.607  48.402  1   14.572 ? 518  VAL A CA  1 
ATOM   3991 C  C   . VAL A 1 526 ? -4.982  12.76   46.917  1   13.731 ? 518  VAL A C   1 
ATOM   3992 O  O   . VAL A 1 526 ? -3.944  13.319  46.561  1   16.67  ? 518  VAL A O   1 
ATOM   3993 C  CB  . VAL A 1 526 ? -4.055  12.009  49.134  1   15.547 ? 518  VAL A CB  1 
ATOM   3994 C  CG1 . VAL A 1 526 ? -4.313  11.943  50.635  1   16.599 ? 518  VAL A CG1 1 
ATOM   3995 C  CG2 . VAL A 1 526 ? -3.648  10.632  48.589  1   14.239 ? 518  VAL A CG2 1 
ATOM   3996 N  N   . THR A 1 527 ? -5.884  12.297  46.042  1   13.856 ? 519  THR A N   1 
ATOM   3997 C  CA  . THR A 1 527 ? -5.628  12.272  44.624  1   13.846 ? 519  THR A CA  1 
ATOM   3998 C  C   . THR A 1 527 ? -6.371  13.451  44.015  1   13.931 ? 519  THR A C   1 
ATOM   3999 O  O   . THR A 1 527 ? -7.603  13.431  44.04   1   14.113 ? 519  THR A O   1 
ATOM   4000 C  CB  . THR A 1 527 ? -6.085  10.941  44.015  1   14.382 ? 519  THR A CB  1 
ATOM   4001 O  OG1 . THR A 1 527 ? -5.334  9.902   44.668  1   12.859 ? 519  THR A OG1 1 
ATOM   4002 C  CG2 . THR A 1 527 ? -5.76   10.854  42.53   1   14.732 ? 519  THR A CG2 1 
ATOM   4003 N  N   . PRO A 1 528 ? -5.676  14.445  43.407  1   13.407 ? 520  PRO A N   1 
ATOM   4004 C  CA  . PRO A 1 528 ? -6.398  15.545  42.759  1   13.218 ? 520  PRO A CA  1 
ATOM   4005 C  C   . PRO A 1 528 ? -7.411  15.049  41.764  1   13.508 ? 520  PRO A C   1 
ATOM   4006 O  O   . PRO A 1 528 ? -7.114  14.176  40.966  1   14.177 ? 520  PRO A O   1 
ATOM   4007 C  CB  . PRO A 1 528 ? -5.276  16.344  42.079  1   12.701 ? 520  PRO A CB  1 
ATOM   4008 C  CG  . PRO A 1 528 ? -4.104  16.134  43.001  1   13.742 ? 520  PRO A CG  1 
ATOM   4009 C  CD  . PRO A 1 528 ? -4.211  14.593  43.336  1   12.688 ? 520  PRO A CD  1 
ATOM   4010 N  N   . ASP A 1 529 ? -8.637  15.611  41.834  1   13.814 ? 521  ASP A N   1 
ATOM   4011 C  CA  . ASP A 1 529 ? -9.685  15.364  40.858  1   13.479 ? 521  ASP A CA  1 
ATOM   4012 C  C   . ASP A 1 529 ? -10.209 13.92   40.873  1   13.037 ? 521  ASP A C   1 
ATOM   4013 O  O   . ASP A 1 529 ? -10.892 13.537  39.929  1   14.617 ? 521  ASP A O   1 
ATOM   4014 C  CB  . ASP A 1 529 ? -9.306  15.835  39.463  1   14.92  ? 521  ASP A CB  1 
ATOM   4015 C  CG  . ASP A 1 529 ? -8.832  17.28   39.433  1   19.242 ? 521  ASP A CG  1 
ATOM   4016 O  OD1 . ASP A 1 529 ? -9.667  18.143  39.791  1   20.232 ? 521  ASP A OD1 1 
ATOM   4017 O  OD2 . ASP A 1 529 ? -7.624  17.565  39.208  1   20.339 ? 521  ASP A OD2 1 
ATOM   4018 N  N   . PHE A 1 530 ? -9.937  13.147  41.937  1   13.841 ? 522  PHE A N   1 
ATOM   4019 C  CA  . PHE A 1 530 ? -10.463 11.794  41.987  1   14.926 ? 522  PHE A CA  1 
ATOM   4020 C  C   . PHE A 1 530 ? -11.989 11.75   41.882  1   15.688 ? 522  PHE A C   1 
ATOM   4021 O  O   . PHE A 1 530 ? -12.53  10.79   41.323  1   16.421 ? 522  PHE A O   1 
ATOM   4022 C  CB  . PHE A 1 530 ? -10.023 11.134  43.294  1   14.596 ? 522  PHE A CB  1 
ATOM   4023 C  CG  . PHE A 1 530 ? -10.281 9.633   43.382  1   14.337 ? 522  PHE A CG  1 
ATOM   4024 C  CD1 . PHE A 1 530 ? -9.341  8.715   42.908  1   13.688 ? 522  PHE A CD1 1 
ATOM   4025 C  CD2 . PHE A 1 530 ? -11.502 9.142   43.9    1   15.82  ? 522  PHE A CD2 1 
ATOM   4026 C  CE1 . PHE A 1 530 ? -9.564  7.349   43.022  1   15.154 ? 522  PHE A CE1 1 
ATOM   4027 C  CE2 . PHE A 1 530 ? -11.758 7.757   43.935  1   13.333 ? 522  PHE A CE2 1 
ATOM   4028 C  CZ  . PHE A 1 530 ? -10.769 6.854   43.518  1   14.09  ? 522  PHE A CZ  1 
ATOM   4029 N  N   . GLU A 1 531 ? -12.644 12.804  42.404  1   17.911 ? 523  GLU A N   1 
ATOM   4030 C  CA  . GLU A 1 531 ? -14.105 12.768  42.333  1   22.476 ? 523  GLU A CA  1 
ATOM   4031 C  C   . GLU A 1 531 ? -14.633 12.881  40.896  1   23.674 ? 523  GLU A C   1 
ATOM   4032 O  O   . GLU A 1 531 ? -15.764 12.491  40.643  1   27.935 ? 523  GLU A O   1 
ATOM   4033 C  CB  . GLU A 1 531 ? -14.662 13.822  43.289  1   24.403 ? 523  GLU A CB  1 
ATOM   4034 C  CG  . GLU A 1 531 ? -16.153 13.653  43.586  1   40.235 ? 523  GLU A CG  1 
ATOM   4035 C  CD  . GLU A 1 531 ? -16.759 12.255  43.778  1   47.759 ? 523  GLU A CD  1 
ATOM   4036 O  OE1 . GLU A 1 531 ? -17.707 11.874  43.027  1   45.549 ? 523  GLU A OE1 1 
ATOM   4037 O  OE2 . GLU A 1 531 ? -16.259 11.522  44.669  1   37.127 ? 523  GLU A OE2 1 
ATOM   4038 N  N   . THR A 1 532 ? -13.866 13.431  39.957  1   19.557 ? 524  THR A N   1 
ATOM   4039 C  CA  . THR A 1 532 ? -14.408 13.716  38.628  1   18.619 ? 524  THR A CA  1 
ATOM   4040 C  C   . THR A 1 532 ? -13.682 12.997  37.498  1   19.811 ? 524  THR A C   1 
ATOM   4041 O  O   . THR A 1 532 ? -14.191 12.983  36.369  1   21.187 ? 524  THR A O   1 
ATOM   4042 C  CB  . THR A 1 532 ? -14.446 15.221  38.332  1   19.694 ? 524  THR A CB  1 
ATOM   4043 O  OG1 . THR A 1 532 ? -13.116 15.741  38.308  1   19.845 ? 524  THR A OG1 1 
ATOM   4044 C  CG2 . THR A 1 532 ? -15.328 15.984  39.308  1   21.129 ? 524  THR A CG2 1 
ATOM   4045 N  N   . LYS A 1 533 ? -12.463 12.506  37.762  1   19.227 ? 525  LYS A N   1 
ATOM   4046 C  CA  . LYS A 1 533 ? -11.683 11.939  36.671  1   20.321 ? 525  LYS A CA  1 
ATOM   4047 C  C   . LYS A 1 533 ? -11.477 10.455  36.937  1   18.074 ? 525  LYS A C   1 
ATOM   4048 O  O   . LYS A 1 533 ? -10.954 10.066  37.987  1   22.368 ? 525  LYS A O   1 
ATOM   4049 C  CB  . LYS A 1 533 ? -10.307 12.617  36.536  1   18.757 ? 525  LYS A CB  1 
ATOM   4050 C  CG  . LYS A 1 533 ? -10.437 14.064  36.03   1   22.394 ? 525  LYS A CG  1 
ATOM   4051 C  CD  . LYS A 1 533 ? -9.113  14.721  35.718  1   28.166 ? 525  LYS A CD  1 
ATOM   4052 C  CE  . LYS A 1 533 ? -9.212  16.185  35.524  1   36.887 ? 525  LYS A CE  1 
ATOM   4053 N  NZ  . LYS A 1 533 ? -7.914  16.529  34.933  1   48.175 ? 525  LYS A NZ  1 
ATOM   4054 N  N   . GLY A 1 534 ? -11.808 9.63    35.948  1   16.992 ? 526  GLY A N   1 
ATOM   4055 C  CA  . GLY A 1 534 ? -11.444 8.213   35.951  1   17.222 ? 526  GLY A CA  1 
ATOM   4056 C  C   . GLY A 1 534 ? -10.096 7.994   35.248  1   15.152 ? 526  GLY A C   1 
ATOM   4057 O  O   . GLY A 1 534 ? -9.525  8.886   34.632  1   16.27  ? 526  GLY A O   1 
ATOM   4058 N  N   . LEU A 1 535 ? -9.653  6.733   35.276  1   13.295 ? 527  LEU A N   1 
ATOM   4059 C  CA  . LEU A 1 535 ? -8.506  6.312   34.48   1   13.874 ? 527  LEU A CA  1 
ATOM   4060 C  C   . LEU A 1 535 ? -8.857  6.288   33.007  1   13.5   ? 527  LEU A C   1 
ATOM   4061 O  O   . LEU A 1 535 ? -7.936  6.399   32.203  1   16.495 ? 527  LEU A O   1 
ATOM   4062 C  CB  . LEU A 1 535 ? -8.032  4.916   34.883  1   13.594 ? 527  LEU A CB  1 
ATOM   4063 C  CG  . LEU A 1 535 ? -7.511  4.757   36.317  1   13.399 ? 527  LEU A CG  1 
ATOM   4064 C  CD1 . LEU A 1 535 ? -7.013  3.347   36.512  1   14.151 ? 527  LEU A CD1 1 
ATOM   4065 C  CD2 . LEU A 1 535 ? -6.391  5.774   36.654  1   13.961 ? 527  LEU A CD2 1 
ATOM   4066 N  N   . VAL A 1 536 ? -10.149 6.13    32.634  1   14.895 ? 528  VAL A N   1 
ATOM   4067 C  CA  . VAL A 1 536 ? -10.571 6.086   31.237  1   14.96  ? 528  VAL A CA  1 
ATOM   4068 C  C   . VAL A 1 536 ? -11.506 7.289   31.021  1   16.327 ? 528  VAL A C   1 
ATOM   4069 O  O   . VAL A 1 536 ? -12.457 7.453   31.771  1   19.594 ? 528  VAL A O   1 
ATOM   4070 C  CB  . VAL A 1 536 ? -11.265 4.748   30.929  1   16.212 ? 528  VAL A CB  1 
ATOM   4071 C  CG1 . VAL A 1 536 ? -11.783 4.718   29.476  1   17.565 ? 528  VAL A CG1 1 
ATOM   4072 C  CG2 . VAL A 1 536 ? -10.413 3.547   31.326  1   15.919 ? 528  VAL A CG2 1 
ATOM   4073 N  N   . ASP A 1 537 ? -11.241 8.117   30.015  1   21.77  ? 529  ASP A N   1 
ATOM   4074 C  CA  . ASP A 1 537 ? -12.204 9.194   29.756  1   21.735 ? 529  ASP A CA  1 
ATOM   4075 C  C   . ASP A 1 537 ? -13.429 8.633   29.036  1   18.711 ? 529  ASP A C   1 
ATOM   4076 O  O   . ASP A 1 537 ? -13.281 7.794   28.147  1   20.115 ? 529  ASP A O   1 
ATOM   4077 C  CB  . ASP A 1 537 ? -11.615 10.311  28.917  1   25.301 ? 529  ASP A CB  1 
ATOM   4078 C  CG  . ASP A 1 537 ? -10.71  11.257  29.679  1   35.558 ? 529  ASP A CG  1 
ATOM   4079 O  OD1 . ASP A 1 537 ? -10.881 11.367  30.916  1   31.152 ? 529  ASP A OD1 1 
ATOM   4080 O  OD2 . ASP A 1 537 ? -9.823  11.833  29.025  1   43.709 ? 529  ASP A OD2 1 
ATOM   4081 N  N   . LEU A 1 538 ? -14.603 9.076   29.469  1   21.504 ? 530  LEU A N   1 
ATOM   4082 C  CA  . LEU A 1 538 ? -15.833 8.59    28.884  1   17.644 ? 530  LEU A CA  1 
ATOM   4083 C  C   . LEU A 1 538 ? -16.019 9.134   27.476  1   16.517 ? 530  LEU A C   1 
ATOM   4084 O  O   . LEU A 1 538 ? -15.578 10.264  27.167  1   19.79  ? 530  LEU A O   1 
ATOM   4085 C  CB  . LEU A 1 538 ? -17.059 8.897   29.732  1   21.538 ? 530  LEU A CB  1 
ATOM   4086 C  CG  . LEU A 1 538 ? -17.096 8.255   31.117  1   24.13  ? 530  LEU A CG  1 
ATOM   4087 C  CD1 . LEU A 1 538 ? -18.33  8.845   31.771  1   26.848 ? 530  LEU A CD1 1 
ATOM   4088 C  CD2 . LEU A 1 538 ? -17.112 6.722   31.08   1   24.948 ? 530  LEU A CD2 1 
ATOM   4089 N  N   . PRO A 1 539 ? -16.662 8.358   26.589  1   15.722 ? 531  PRO A N   1 
ATOM   4090 C  CA  . PRO A 1 539 ? -17.027 8.895   25.277  1   16.169 ? 531  PRO A CA  1 
ATOM   4091 C  C   . PRO A 1 539 ? -18.144 9.915   25.47   1   16.254 ? 531  PRO A C   1 
ATOM   4092 O  O   . PRO A 1 539 ? -18.751 10.025  26.537  1   16.425 ? 531  PRO A O   1 
ATOM   4093 C  CB  . PRO A 1 539 ? -17.51  7.672   24.469  1   18.463 ? 531  PRO A CB  1 
ATOM   4094 C  CG  . PRO A 1 539 ? -17.861 6.658   25.522  1   20.912 ? 531  PRO A CG  1 
ATOM   4095 C  CD  . PRO A 1 539 ? -17.101 6.953   26.818  1   17.884 ? 531  PRO A CD  1 
ATOM   4096 N  N   . LYS A 1 540 ? -18.39  10.675  24.399  1   17.737 ? 532  LYS A N   1 
ATOM   4097 C  CA  . LYS A 1 540 ? -19.375 11.743  24.473  1   18.313 ? 532  LYS A CA  1 
ATOM   4098 C  C   . LYS A 1 540 ? -20.804 11.207  24.654  1   16.508 ? 532  LYS A C   1 
ATOM   4099 O  O   . LYS A 1 540 ? -21.166 10.089  24.237  1   16.447 ? 532  LYS A O   1 
ATOM   4100 C  CB  . LYS A 1 540 ? -19.206 12.609  23.219  1   17.471 ? 532  LYS A CB  1 
ATOM   4101 C  CG  . LYS A 1 540 ? -19.806 12.061  21.918  1   18.655 ? 532  LYS A CG  1 
ATOM   4102 C  CD  . LYS A 1 540 ? -19.709 13.122  20.809  1   18.288 ? 532  LYS A CD  1 
ATOM   4103 C  CE  . LYS A 1 540 ? -20.365 12.625  19.562  1   19.312 ? 532  LYS A CE  1 
ATOM   4104 N  NZ  . LYS A 1 540 ? -20.325 13.761  18.585  1   20.597 ? 532  LYS A NZ  1 
ATOM   4105 N  N   . GLU A 1 541 ? -21.639 12.078  25.227  1   17.496 ? 533  GLU A N   1 
ATOM   4106 C  CA  . GLU A 1 541 ? -23.036 11.726  25.452  1   16.551 ? 533  GLU A CA  1 
ATOM   4107 C  C   . GLU A 1 541 ? -23.871 11.733  24.159  1   18.194 ? 533  GLU A C   1 
ATOM   4108 O  O   . GLU A 1 541 ? -24.652 10.791  23.938  1   19.754 ? 533  GLU A O   1 
ATOM   4109 C  CB  . GLU A 1 541 ? -23.647 12.677  26.474  1   18.67  ? 533  GLU A CB  1 
ATOM   4110 C  CG  . GLU A 1 541 ? -25.088 12.309  26.837  1   23.092 ? 533  GLU A CG  1 
ATOM   4111 C  CD  . GLU A 1 541 ? -25.698 13.156  27.959  1   29.027 ? 533  GLU A CD  1 
ATOM   4112 O  OE1 . GLU A 1 541 ? -25.071 14.099  28.462  1   31.752 ? 533  GLU A OE1 1 
ATOM   4113 O  OE2 . GLU A 1 541 ? -26.792 12.764  28.389  1   35.702 ? 533  GLU A OE2 1 
ATOM   4114 N  N   . GLU A 1 542 ? -23.721 12.801  23.34   1   18.136 ? 534  GLU A N   1 
ATOM   4115 C  CA  . GLU A 1 542 ? -24.566 12.964  22.164  1   20.031 ? 534  GLU A CA  1 
ATOM   4116 C  C   . GLU A 1 542 ? -24.408 11.745  21.245  1   17.315 ? 534  GLU A C   1 
ATOM   4117 O  O   . GLU A 1 542 ? -23.281 11.305  21.002  1   17.111 ? 534  GLU A O   1 
ATOM   4118 C  CB  . GLU A 1 542 ? -24.097 14.228  21.434  1   22.45  ? 534  GLU A CB  1 
ATOM   4119 C  CG  . GLU A 1 542 ? -24.987 14.634  20.261  1   34.635 ? 534  GLU A CG  1 
ATOM   4120 C  CD  . GLU A 1 542 ? -24.685 16.031  19.72   1   44.004 ? 534  GLU A CD  1 
ATOM   4121 O  OE1 . GLU A 1 542 ? -23.496 16.352  19.497  1   44.639 ? 534  GLU A OE1 1 
ATOM   4122 O  OE2 . GLU A 1 542 ? -25.672 16.785  19.536  1   53.555 ? 534  GLU A OE2 1 
ATOM   4123 N  N   . HIS A 1 543 ? -25.527 11.259  20.69   1   17.843 ? 535  HIS A N   1 
ATOM   4124 C  CA  . HIS A 1 543 ? -25.442 10.186  19.695  1   16.13  ? 535  HIS A CA  1 
ATOM   4125 C  C   . HIS A 1 543 ? -24.8   10.694  18.406  1   17.169 ? 535  HIS A C   1 
ATOM   4126 O  O   . HIS A 1 543 ? -25.013 11.863  17.999  1   19.976 ? 535  HIS A O   1 
ATOM   4127 C  CB  . HIS A 1 543 ? -26.849 9.644   19.359  1   17.986 ? 535  HIS A CB  1 
ATOM   4128 C  CG  . HIS A 1 543 ? -27.541 9.026   20.508  1   19.563 ? 535  HIS A CG  1 
ATOM   4129 N  ND1 . HIS A 1 543 ? -26.87  8.235   21.419  1   16.971 ? 535  HIS A ND1 1 
ATOM   4130 C  CD2 . HIS A 1 543 ? -28.837 9.097   20.957  1   19.19  ? 535  HIS A CD2 1 
ATOM   4131 C  CE1 . HIS A 1 543 ? -27.762 7.77    22.322  1   19.08  ? 535  HIS A CE1 1 
ATOM   4132 N  NE2 . HIS A 1 543 ? -28.973 8.319   22.064  1   18.755 ? 535  HIS A NE2 1 
ATOM   4133 N  N   . TRP A 1 544 ? -24.051 9.796   17.732  1   15.179 ? 536  TRP A N   1 
ATOM   4134 C  CA  . TRP A 1 544 ? -23.554 10.106  16.397  1   15.029 ? 536  TRP A CA  1 
ATOM   4135 C  C   . TRP A 1 544 ? -24.694 10.113  15.386  1   19.044 ? 536  TRP A C   1 
ATOM   4136 O  O   . TRP A 1 544 ? -24.662 10.894  14.418  1   20.724 ? 536  TRP A O   1 
ATOM   4137 C  CB  . TRP A 1 544 ? -22.514 9.082   15.918  1   15.378 ? 536  TRP A CB  1 
ATOM   4138 C  CG  . TRP A 1 544 ? -21.254 8.996   16.747  1   16.604 ? 536  TRP A CG  1 
ATOM   4139 C  CD1 . TRP A 1 544 ? -20.891 7.981   17.582  1   15.418 ? 536  TRP A CD1 1 
ATOM   4140 C  CD2 . TRP A 1 544 ? -20.137 9.931   16.721  1   16.294 ? 536  TRP A CD2 1 
ATOM   4141 N  NE1 . TRP A 1 544 ? -19.645 8.251   18.129  1   16.893 ? 536  TRP A NE1 1 
ATOM   4142 C  CE2 . TRP A 1 544 ? -19.16  9.42    17.612  1   16.757 ? 536  TRP A CE2 1 
ATOM   4143 C  CE3 . TRP A 1 544 ? -19.864 11.154  16.068  1   18.204 ? 536  TRP A CE3 1 
ATOM   4144 C  CZ2 . TRP A 1 544 ? -17.948 10.069  17.836  1   17.583 ? 536  TRP A CZ2 1 
ATOM   4145 C  CZ3 . TRP A 1 544 ? -18.657 11.815  16.328  1   18.738 ? 536  TRP A CZ3 1 
ATOM   4146 C  CH2 . TRP A 1 544 ? -17.708 11.283  17.221  1   17.842 ? 536  TRP A CH2 1 
ATOM   4147 N  N   . ALA A 1 545 ? -25.581 9.132   15.484  1   17.231 ? 537  ALA A N   1 
ATOM   4148 C  CA  . ALA A 1 545 ? -26.565 8.888   14.435  1   17.326 ? 537  ALA A CA  1 
ATOM   4149 C  C   . ALA A 1 545 ? -27.802 9.747   14.667  1   19.644 ? 537  ALA A C   1 
ATOM   4150 O  O   . ALA A 1 545 ? -28.195 9.962   15.803  1   20.308 ? 537  ALA A O   1 
ATOM   4151 C  CB  . ALA A 1 545 ? -26.987 7.443   14.469  1   16.447 ? 537  ALA A CB  1 
ATOM   4152 N  N   . PRO A 1 546 ? -28.472 10.227  13.587  1   20.051 ? 538  PRO A N   1 
ATOM   4153 C  CA  . PRO A 1 546 ? -29.77  10.902  13.755  1   20.756 ? 538  PRO A CA  1 
ATOM   4154 C  C   . PRO A 1 546 ? -30.863 9.917   14.152  1   19.752 ? 538  PRO A C   1 
ATOM   4155 O  O   . PRO A 1 546 ? -30.801 8.709   13.858  1   20.449 ? 538  PRO A O   1 
ATOM   4156 C  CB  . PRO A 1 546 ? -30.015 11.504  12.351  1   20.964 ? 538  PRO A CB  1 
ATOM   4157 C  CG  . PRO A 1 546 ? -29.345 10.54   11.424  1   21.319 ? 538  PRO A CG  1 
ATOM   4158 C  CD  . PRO A 1 546 ? -28.066 10.1    12.189  1   20.275 ? 538  PRO A CD  1 
ATOM   4159 N  N   . LEU A 1 547 ? -31.896 10.473  14.809  1   21.229 ? 539  LEU A N   1 
ATOM   4160 C  CA  . LEU A 1 547 ? -33.024 9.678   15.261  1   22.433 ? 539  LEU A CA  1 
ATOM   4161 C  C   . LEU A 1 547 ? -33.639 8.834   14.141  1   22.352 ? 539  LEU A C   1 
ATOM   4162 O  O   . LEU A 1 547 ? -34.025 7.695   14.384  1   22.799 ? 539  LEU A O   1 
ATOM   4163 C  CB  . LEU A 1 547 ? -34.055 10.64   15.866  1   25.466 ? 539  LEU A CB  1 
ATOM   4164 C  CG  . LEU A 1 547 ? -35.307 9.98    16.474  1   28.742 ? 539  LEU A CG  1 
ATOM   4165 C  CD1 . LEU A 1 547 ? -35.003 9.073   17.687  1   28.747 ? 539  LEU A CD1 1 
ATOM   4166 C  CD2 . LEU A 1 547 ? -36.413 11.025  16.778  1   29.859 ? 539  LEU A CD2 1 
ATOM   4167 N  N   . SER A 1 548 ? -33.667 9.38    12.922  1   23.313 ? 540  SER A N   1 
ATOM   4168 C  CA  . SER A 1 548 ? -34.31  8.759   11.773  1   24.39  ? 540  SER A CA  1 
ATOM   4169 C  C   . SER A 1 548 ? -33.673 7.429   11.375  1   22.629 ? 540  SER A C   1 
ATOM   4170 O  O   . SER A 1 548 ? -34.303 6.624   10.709  1   24.217 ? 540  SER A O   1 
ATOM   4171 C  CB  . SER A 1 548 ? -34.307 9.699   10.579  1   27.021 ? 540  SER A CB  1 
ATOM   4172 O  OG  . SER A 1 548 ? -32.973 10.028  10.174  1   25.511 ? 540  SER A OG  1 
ATOM   4173 N  N   . GLN A 1 549 ? -32.408 7.185   11.787  1   19.785 ? 541  GLN A N   1 
ATOM   4174 C  CA  . GLN A 1 549 ? -31.745 5.957   11.376  1   18.388 ? 541  GLN A CA  1 
ATOM   4175 C  C   . GLN A 1 549 ? -32.107 4.749   12.25   1   17.409 ? 541  GLN A C   1 
ATOM   4176 O  O   . GLN A 1 549 ? -31.71  3.643   11.89   1   19.346 ? 541  GLN A O   1 
ATOM   4177 C  CB  . GLN A 1 549 ? -30.243 6.241   11.44   1   15.698 ? 541  GLN A CB  1 
ATOM   4178 C  CG  . GLN A 1 549 ? -29.764 7.002   10.202  1   17.346 ? 541  GLN A CG  1 
ATOM   4179 C  CD  . GLN A 1 549 ? -29.432 6.08    9.04    1   19.762 ? 541  GLN A CD  1 
ATOM   4180 O  OE1 . GLN A 1 549 ? -28.679 5.087   9.134   1   17.034 ? 541  GLN A OE1 1 
ATOM   4181 N  NE2 . GLN A 1 549 ? -30.039 6.376   7.879   1   18.958 ? 541  GLN A NE2 1 
ATOM   4182 N  N   . SER A 1 550 ? -32.854 4.918   13.353  1   19.245 ? 542  SER A N   1 
ATOM   4183 C  CA  . SER A 1 550 ? -33.177 3.74    14.157  1   19.838 ? 542  SER A CA  1 
ATOM   4184 C  C   . SER A 1 550 ? -33.981 2.715   13.359  1   18.39  ? 542  SER A C   1 
ATOM   4185 O  O   . SER A 1 550 ? -34.885 3.108   12.599  1   18.076 ? 542  SER A O   1 
ATOM   4186 C  CB  . SER A 1 550 ? -33.951 4.09    15.376  1   20.989 ? 542  SER A CB  1 
ATOM   4187 O  OG  . SER A 1 550 ? -34.141 2.948   16.22   1   22.547 ? 542  SER A OG  1 
ATOM   4188 N  N   . PRO A 1 551 ? -33.702 1.401   13.504  1   18.491 ? 543  PRO A N   1 
ATOM   4189 C  CA  . PRO A 1 551 ? -34.554 0.373   12.919  1   19.148 ? 543  PRO A CA  1 
ATOM   4190 C  C   . PRO A 1 551 ? -35.97  0.387   13.499  1   17.862 ? 543  PRO A C   1 
ATOM   4191 O  O   . PRO A 1 551 ? -36.897 -0.077  12.833  1   18.549 ? 543  PRO A O   1 
ATOM   4192 C  CB  . PRO A 1 551 ? -33.849 -0.979  13.171  1   19.963 ? 543  PRO A CB  1 
ATOM   4193 C  CG  . PRO A 1 551 ? -32.942 -0.681  14.379  1   19.977 ? 543  PRO A CG  1 
ATOM   4194 C  CD  . PRO A 1 551 ? -32.554 0.784   14.244  1   18.106 ? 543  PRO A CD  1 
ATOM   4195 N  N   . TYR A 1 552 ? -36.105 0.893   14.719  1   17.295 ? 544  TYR A N   1 
ATOM   4196 C  CA  . TYR A 1 552 ? -37.378 0.82    15.434  1   17.899 ? 544  TYR A CA  1 
ATOM   4197 C  C   . TYR A 1 552 ? -38.254 2.028   15.13   1   20.314 ? 544  TYR A C   1 
ATOM   4198 O  O   . TYR A 1 552 ? -37.813 3.173   15.175  1   19.9   ? 544  TYR A O   1 
ATOM   4199 C  CB  . TYR A 1 552 ? -37.034 0.717   16.923  1   18.236 ? 544  TYR A CB  1 
ATOM   4200 C  CG  . TYR A 1 552 ? -38.167 1.063   17.884  1   18.68  ? 544  TYR A CG  1 
ATOM   4201 C  CD1 . TYR A 1 552 ? -39.142 0.088   18.189  1   20.961 ? 544  TYR A CD1 1 
ATOM   4202 C  CD2 . TYR A 1 552 ? -38.253 2.329   18.457  1   20.329 ? 544  TYR A CD2 1 
ATOM   4203 C  CE1 . TYR A 1 552 ? -40.145 0.388   19.099  1   19.681 ? 544  TYR A CE1 1 
ATOM   4204 C  CE2 . TYR A 1 552 ? -39.271 2.633   19.359  1   19.668 ? 544  TYR A CE2 1 
ATOM   4205 C  CZ  . TYR A 1 552 ? -40.185 1.637   19.689  1   19.094 ? 544  TYR A CZ  1 
ATOM   4206 O  OH  . TYR A 1 552 ? -41.207 1.932   20.587  1   21.332 ? 544  TYR A OH  1 
ATOM   4207 N  N   . ASP A 1 553 ? -39.567 1.734   14.978  1   21.919 ? 545  ASP A N   1 
ATOM   4208 C  CA  . ASP A 1 553 ? -40.586 2.761   14.827  1   22.704 ? 545  ASP A CA  1 
ATOM   4209 C  C   . ASP A 1 553 ? -41.641 2.542   15.911  1   19.277 ? 545  ASP A C   1 
ATOM   4210 O  O   . ASP A 1 553 ? -42.226 1.455   15.897  1   20.543 ? 545  ASP A O   1 
ATOM   4211 C  CB  . ASP A 1 553 ? -41.174 2.683   13.426  1   22.341 ? 545  ASP A CB  1 
ATOM   4212 C  CG  . ASP A 1 553 ? -42.352 3.604   13.155  1   24.947 ? 545  ASP A CG  1 
ATOM   4213 O  OD1 . ASP A 1 553 ? -42.783 4.32    14.083  1   24.316 ? 545  ASP A OD1 1 
ATOM   4214 O  OD2 . ASP A 1 553 ? -42.782 3.622   11.988  1   33.394 ? 545  ASP A OD2 1 
ATOM   4215 N  N   . PRO A 1 554 ? -41.886 3.498   16.851  1   21.871 ? 546  PRO A N   1 
ATOM   4216 C  CA  . PRO A 1 554 ? -42.878 3.283   17.919  1   22.436 ? 546  PRO A CA  1 
ATOM   4217 C  C   . PRO A 1 554 ? -44.299 3.031   17.425  1   20.711 ? 546  PRO A C   1 
ATOM   4218 O  O   . PRO A 1 554 ? -45.102 2.485   18.173  1   22.476 ? 546  PRO A O   1 
ATOM   4219 C  CB  . PRO A 1 554 ? -42.821 4.534   18.816  1   22.356 ? 546  PRO A CB  1 
ATOM   4220 C  CG  . PRO A 1 554 ? -42.234 5.586   17.88   1   27.256 ? 546  PRO A CG  1 
ATOM   4221 C  CD  . PRO A 1 554 ? -41.266 4.827   16.942  1   24.863 ? 546  PRO A CD  1 
ATOM   4222 N  N   . ASP A 1 555 ? -44.562 3.377   16.148  1   22.178 ? 547  ASP A N   1 
ATOM   4223 C  CA  . ASP A 1 555 ? -45.891 3.211   15.544  1   22.432 ? 547  ASP A CA  1 
ATOM   4224 C  C   . ASP A 1 555 ? -46.054 1.871   14.841  1   21.765 ? 547  ASP A C   1 
ATOM   4225 O  O   . ASP A 1 555 ? -47.175 1.472   14.517  1   24.018 ? 547  ASP A O   1 
ATOM   4226 C  CB  . ASP A 1 555 ? -46.288 4.407   14.671  1   21.002 ? 547  ASP A CB  1 
ATOM   4227 C  CG  . ASP A 1 555 ? -46.336 5.713   15.445  1   24.459 ? 547  ASP A CG  1 
ATOM   4228 O  OD1 . ASP A 1 555 ? -46.987 5.711   16.522  1   25.645 ? 547  ASP A OD1 1 
ATOM   4229 O  OD2 . ASP A 1 555 ? -45.799 6.725   14.968  1   32.575 ? 547  ASP A OD2 1 
ATOM   4230 N  N   . ALA A 1 556 ? -44.975 1.138   14.626  1   21.484 ? 548  ALA A N   1 
ATOM   4231 C  CA  . ALA A 1 556 ? -45.029 -0.083  13.856  1   20.985 ? 548  ALA A CA  1 
ATOM   4232 C  C   . ALA A 1 556 ? -45.574 -1.245  14.695  1   22.973 ? 548  ALA A C   1 
ATOM   4233 O  O   . ALA A 1 556 ? -45.962 -2.235  14.074  1   27.678 ? 548  ALA A O   1 
ATOM   4234 C  CB  . ALA A 1 556 ? -43.592 -0.36   13.329  1   19.676 ? 548  ALA A CB  1 
ATOM   4235 O  OXT . ALA A 1 556 ? -45.529 -1.184  15.954  1   24.321 ? 548  ALA A OXT 1 
ATOM   4236 N  N   . TYR B 1 32  ? -4.739  -28.517 41.647  1   31.516 ? 24   TYR B N   1 
ATOM   4237 C  CA  . TYR B 1 32  ? -5.764  -28.123 42.664  1   26.987 ? 24   TYR B CA  1 
ATOM   4238 C  C   . TYR B 1 32  ? -6.525  -26.91  42.145  1   32.227 ? 24   TYR B C   1 
ATOM   4239 O  O   . TYR B 1 32  ? -5.908  -26.014 41.573  1   31.349 ? 24   TYR B O   1 
ATOM   4240 C  CB  . TYR B 1 32  ? -5.114  -27.709 43.983  1   27.562 ? 24   TYR B CB  1 
ATOM   4241 C  CG  . TYR B 1 32  ? -4.433  -28.857 44.713  1   29.03  ? 24   TYR B CG  1 
ATOM   4242 C  CD1 . TYR B 1 32  ? -5.177  -29.912 45.289  1   26.693 ? 24   TYR B CD1 1 
ATOM   4243 C  CD2 . TYR B 1 32  ? -3.039  -28.882 44.85   1   28.941 ? 24   TYR B CD2 1 
ATOM   4244 C  CE1 . TYR B 1 32  ? -4.564  -30.969 45.946  1   27.482 ? 24   TYR B CE1 1 
ATOM   4245 C  CE2 . TYR B 1 32  ? -2.406  -29.937 45.51   1   32.141 ? 24   TYR B CE2 1 
ATOM   4246 C  CZ  . TYR B 1 32  ? -3.178  -30.955 46.075  1   28.928 ? 24   TYR B CZ  1 
ATOM   4247 O  OH  . TYR B 1 32  ? -2.533  -31.928 46.739  1   26.895 ? 24   TYR B OH  1 
ATOM   4248 N  N   . VAL B 1 33  ? -7.843  -26.902 42.368  1   28.142 ? 25   VAL B N   1 
ATOM   4249 C  CA  . VAL B 1 33  ? -8.725  -25.788 42.017  1   27.322 ? 25   VAL B CA  1 
ATOM   4250 C  C   . VAL B 1 33  ? -8.265  -24.617 42.894  1   26.285 ? 25   VAL B C   1 
ATOM   4251 O  O   . VAL B 1 33  ? -7.86   -24.773 44.056  1   26.636 ? 25   VAL B O   1 
ATOM   4252 C  CB  . VAL B 1 33  ? -10.213 -26.144 42.222  1   29.484 ? 25   VAL B CB  1 
ATOM   4253 C  CG1 . VAL B 1 33  ? -11.193 -24.967 42.02   1   35.979 ? 25   VAL B CG1 1 
ATOM   4254 C  CG2 . VAL B 1 33  ? -10.651 -27.28  41.29   1   31.422 ? 25   VAL B CG2 1 
ATOM   4255 N  N   . HIS B 1 34  ? -8.29   -23.422 42.3    1   23.229 ? 26   HIS B N   1 
ATOM   4256 C  CA  . HIS B 1 34  ? -7.934  -22.222 43.036  1   21.631 ? 26   HIS B CA  1 
ATOM   4257 C  C   . HIS B 1 34  ? -9.155  -21.704 43.794  1   21.123 ? 26   HIS B C   1 
ATOM   4258 O  O   . HIS B 1 34  ? -10.185 -21.48  43.183  1   21.451 ? 26   HIS B O   1 
ATOM   4259 C  CB  . HIS B 1 34  ? -7.363  -21.211 42.034  1   20.722 ? 26   HIS B CB  1 
ATOM   4260 C  CG  . HIS B 1 34  ? -6.55   -20.207 42.758  1   20.656 ? 26   HIS B CG  1 
ATOM   4261 N  ND1 . HIS B 1 34  ? -7.095  -19.301 43.653  1   21.892 ? 26   HIS B ND1 1 
ATOM   4262 C  CD2 . HIS B 1 34  ? -5.189  -20.073 42.792  1   21.044 ? 26   HIS B CD2 1 
ATOM   4263 C  CE1 . HIS B 1 34  ? -6.093  -18.634 44.233  1   22.852 ? 26   HIS B CE1 1 
ATOM   4264 N  NE2 . HIS B 1 34  ? -4.936  -19.052 43.685  1   24.511 ? 26   HIS B NE2 1 
ATOM   4265 N  N   . PRO B 1 35  ? -9.097  -21.455 45.125  1   18.979 ? 27   PRO B N   1 
ATOM   4266 C  CA  . PRO B 1 35  ? -10.232 -20.911 45.871  1   19.88  ? 27   PRO B CA  1 
ATOM   4267 C  C   . PRO B 1 35  ? -10.881 -19.655 45.294  1   21.33  ? 27   PRO B C   1 
ATOM   4268 O  O   . PRO B 1 35  ? -12.101 -19.49  45.373  1   19.756 ? 27   PRO B O   1 
ATOM   4269 C  CB  . PRO B 1 35  ? -9.713  -20.658 47.302  1   21.318 ? 27   PRO B CB  1 
ATOM   4270 C  CG  . PRO B 1 35  ? -8.385  -21.34  47.332  1   22.58  ? 27   PRO B CG  1 
ATOM   4271 C  CD  . PRO B 1 35  ? -7.924  -21.716 45.986  1   21.051 ? 27   PRO B CD  1 
ATOM   4272 N  N   . THR B 1 36  ? -10.046 -18.757 44.706  1   19.86  ? 28   THR B N   1 
ATOM   4273 C  CA  . THR B 1 36  ? -10.6   -17.514 44.198  1   19.592 ? 28   THR B CA  1 
ATOM   4274 C  C   . THR B 1 36  ? -11.374 -17.743 42.89   1   18.698 ? 28   THR B C   1 
ATOM   4275 O  O   . THR B 1 36  ? -12.195 -16.885 42.53   1   17.903 ? 28   THR B O   1 
ATOM   4276 C  CB  . THR B 1 36  ? -9.547  -16.409 44.015  1   20.452 ? 28   THR B CB  1 
ATOM   4277 O  OG1 . THR B 1 36  ? -8.665  -16.806 42.968  1   21.866 ? 28   THR B OG1 1 
ATOM   4278 C  CG2 . THR B 1 36  ? -8.736  -16.176 45.286  1   21.817 ? 28   THR B CG2 1 
ATOM   4279 N  N   . ASP B 1 37  ? -11.15  -18.91  42.247  1   19.013 ? 29   ASP B N   1 
ATOM   4280 C  CA  . ASP B 1 37  ? -11.81  -19.189 40.975  1   20.38  ? 29   ASP B CA  1 
ATOM   4281 C  C   . ASP B 1 37  ? -13.277 -19.547 41.141  1   22.276 ? 29   ASP B C   1 
ATOM   4282 O  O   . ASP B 1 37  ? -14.006 -19.489 40.13   1   26.42  ? 29   ASP B O   1 
ATOM   4283 C  CB  . ASP B 1 37  ? -11.104 -20.234 40.132  1   20.71  ? 29   ASP B CB  1 
ATOM   4284 C  CG  . ASP B 1 37  ? -9.804  -19.749 39.521  1   21.231 ? 29   ASP B CG  1 
ATOM   4285 O  OD1 . ASP B 1 37  ? -9.513  -18.502 39.631  1   23.468 ? 29   ASP B OD1 1 
ATOM   4286 O  OD2 . ASP B 1 37  ? -9.067  -20.618 39.047  1   22.25  ? 29   ASP B OD2 1 
ATOM   4287 N  N   . ILE B 1 38  ? -13.658 -19.952 42.361  1   21.586 ? 30   ILE B N   1 
ATOM   4288 C  CA  . ILE B 1 38  ? -15.051 -20.256 42.627  1   22.712 ? 30   ILE B CA  1 
ATOM   4289 C  C   . ILE B 1 38  ? -15.806 -19.064 43.219  1   24.179 ? 30   ILE B C   1 
ATOM   4290 O  O   . ILE B 1 38  ? -17.01  -19.17  43.436  1   23.655 ? 30   ILE B O   1 
ATOM   4291 C  CB  . ILE B 1 38  ? -15.24  -21.597 43.359  1   30.13  ? 30   ILE B CB  1 
ATOM   4292 C  CG1 . ILE B 1 38  ? -14.741 -21.5   44.806  1   30.497 ? 30   ILE B CG1 1 
ATOM   4293 C  CG2 . ILE B 1 38  ? -14.599 -22.733 42.547  1   29.638 ? 30   ILE B CG2 1 
ATOM   4294 C  CD1 . ILE B 1 38  ? -15.041 -22.713 45.684  1   36.862 ? 30   ILE B CD1 1 
ATOM   4295 N  N   . LEU B 1 39  ? -15.151 -17.897 43.402  1   20.23  ? 31   LEU B N   1 
ATOM   4296 C  CA  . LEU B 1 39  ? -15.868 -16.68  43.761  1   20.583 ? 31   LEU B CA  1 
ATOM   4297 C  C   . LEU B 1 39  ? -16.759 -16.285 42.575  1   21.509 ? 31   LEU B C   1 
ATOM   4298 O  O   . LEU B 1 39  ? -16.339 -16.412 41.442  1   21.934 ? 31   LEU B O   1 
ATOM   4299 C  CB  . LEU B 1 39  ? -14.869 -15.565 44.096  1   20.453 ? 31   LEU B CB  1 
ATOM   4300 C  CG  . LEU B 1 39  ? -14.031 -15.775 45.367  1   23.127 ? 31   LEU B CG  1 
ATOM   4301 C  CD1 . LEU B 1 39  ? -12.943 -14.687 45.394  1   22.615 ? 31   LEU B CD1 1 
ATOM   4302 C  CD2 . LEU B 1 39  ? -14.881 -15.685 46.623  1   29.016 ? 31   LEU B CD2 1 
ATOM   4303 N  N   . PRO B 1 40  ? -17.985 -15.798 42.823  1   22.053 ? 32   PRO B N   1 
ATOM   4304 C  CA  . PRO B 1 40  ? -18.914 -15.484 41.736  1   23.451 ? 32   PRO B CA  1 
ATOM   4305 C  C   . PRO B 1 40  ? -18.529 -14.324 40.83   1   24.337 ? 32   PRO B C   1 
ATOM   4306 O  O   . PRO B 1 40  ? -17.977 -13.321 41.254  1   19.907 ? 32   PRO B O   1 
ATOM   4307 C  CB  . PRO B 1 40  ? -20.222 -15.133 42.46   1   23.446 ? 32   PRO B CB  1 
ATOM   4308 C  CG  . PRO B 1 40  ? -19.81  -14.692 43.823  1   27.623 ? 32   PRO B CG  1 
ATOM   4309 C  CD  . PRO B 1 40  ? -18.545 -15.5   44.142  1   21.14  ? 32   PRO B CD  1 
ATOM   4310 N  N   . SER B 1 41  ? -18.939 -14.491 39.583  1   23.338 ? 33   SER B N   1 
ATOM   4311 C  CA  . SER B 1 41  ? -18.753 -13.535 38.514  1   24.09  ? 33   SER B CA  1 
ATOM   4312 C  C   . SER B 1 41  ? -20.159 -13.056 38.144  1   23.521 ? 33   SER B C   1 
ATOM   4313 O  O   . SER B 1 41  ? -21.123 -13.853 38.121  1   25.533 ? 33   SER B O   1 
ATOM   4314 C  CB  . SER B 1 41  ? -18.063 -14.23  37.376  1   23.113 ? 33   SER B CB  1 
ATOM   4315 O  OG  . SER B 1 41  ? -18.063 -13.402 36.214  1   22.248 ? 33   SER B OG  1 
ATOM   4316 N  N   . GLY B 1 42  ? -20.256 -11.752 37.862  1   21.774 ? 34   GLY B N   1 
ATOM   4317 C  CA  . GLY B 1 42  ? -21.448 -11.16  37.276  1   21.195 ? 34   GLY B CA  1 
ATOM   4318 C  C   . GLY B 1 42  ? -21.467 -11.258 35.759  1   21.895 ? 34   GLY B C   1 
ATOM   4319 O  O   . GLY B 1 42  ? -22.414 -10.744 35.173  1   23.612 ? 34   GLY B O   1 
ATOM   4320 N  N   . TRP B 1 43  ? -20.481 -11.891 35.119  1   18.462 ? 35   TRP B N   1 
ATOM   4321 C  CA  . TRP B 1 43  ? -20.513 -11.989 33.669  1   19.11  ? 35   TRP B CA  1 
ATOM   4322 C  C   . TRP B 1 43  ? -21.329 -13.198 33.24   1   20.42  ? 35   TRP B C   1 
ATOM   4323 O  O   . TRP B 1 43  ? -21.093 -14.318 33.722  1   23.566 ? 35   TRP B O   1 
ATOM   4324 C  CB  . TRP B 1 43  ? -19.109 -12.102 33.09   1   16.971 ? 35   TRP B CB  1 
ATOM   4325 C  CG  . TRP B 1 43  ? -18.509 -10.76  32.754  1   16.951 ? 35   TRP B CG  1 
ATOM   4326 C  CD1 . TRP B 1 43  ? -17.924 -9.863  33.622  1   17.24  ? 35   TRP B CD1 1 
ATOM   4327 C  CD2 . TRP B 1 43  ? -18.401 -10.187 31.439  1   16.533 ? 35   TRP B CD2 1 
ATOM   4328 N  NE1 . TRP B 1 43  ? -17.499 -8.749  32.935  1   17.262 ? 35   TRP B NE1 1 
ATOM   4329 C  CE2 . TRP B 1 43  ? -17.775 -8.916  31.607  1   16.972 ? 35   TRP B CE2 1 
ATOM   4330 C  CE3 . TRP B 1 43  ? -18.791 -10.591 30.156  1   16.095 ? 35   TRP B CE3 1 
ATOM   4331 C  CZ2 . TRP B 1 43  ? -17.536 -8.074  30.532  1   15.551 ? 35   TRP B CZ2 1 
ATOM   4332 C  CZ3 . TRP B 1 43  ? -18.549 -9.733  29.083  1   15.574 ? 35   TRP B CZ3 1 
ATOM   4333 C  CH2 . TRP B 1 43  ? -17.937 -8.491  29.288  1   15.454 ? 35   TRP B CH2 1 
ATOM   4334 N  N   . PRO B 1 44  ? -22.225 -13.026 32.237  1   17.81  ? 36   PRO B N   1 
ATOM   4335 C  CA  . PRO B 1 44  ? -22.785 -14.174 31.536  1   21.093 ? 36   PRO B CA  1 
ATOM   4336 C  C   . PRO B 1 44  ? -21.708 -14.67  30.577  1   20.462 ? 36   PRO B C   1 
ATOM   4337 O  O   . PRO B 1 44  ? -20.677 -14.021 30.353  1   21.822 ? 36   PRO B O   1 
ATOM   4338 C  CB  . PRO B 1 44  ? -23.973 -13.518 30.805  1   22.379 ? 36   PRO B CB  1 
ATOM   4339 C  CG  . PRO B 1 44  ? -23.528 -12.124 30.505  1   23.07  ? 36   PRO B CG  1 
ATOM   4340 C  CD  . PRO B 1 44  ? -22.65  -11.714 31.68   1   20.356 ? 36   PRO B CD  1 
ATOM   4341 N  N   . THR B 1 45  ? -21.965 -15.845 30.007  1   20.921 ? 37   THR B N   1 
ATOM   4342 C  CA  . THR B 1 45  ? -21.067 -16.412 29.015  1   20.297 ? 37   THR B CA  1 
ATOM   4343 C  C   . THR B 1 45  ? -21.201 -15.659 27.697  1   20.573 ? 37   THR B C   1 
ATOM   4344 O  O   . THR B 1 45  ? -22.258 -15.696 27.077  1   23.406 ? 37   THR B O   1 
ATOM   4345 C  CB  . THR B 1 45  ? -21.382 -17.9   28.861  1   22.884 ? 37   THR B CB  1 
ATOM   4346 O  OG1 . THR B 1 45  ? -21.144 -18.411 30.175  1   26.424 ? 37   THR B OG1 1 
ATOM   4347 C  CG2 . THR B 1 45  ? -20.454 -18.587 27.887  1   24.473 ? 37   THR B CG2 1 
ATOM   4348 N  N   . ALA B 1 46  ? -20.115 -14.974 27.295  1   18.448 ? 38   ALA B N   1 
ATOM   4349 C  CA  . ALA B 1 46  ? -20.107 -14.118 26.109  1   19.471 ? 38   ALA B CA  1 
ATOM   4350 C  C   . ALA B 1 46  ? -19.143 -14.73  25.107  1   17.626 ? 38   ALA B C   1 
ATOM   4351 O  O   . ALA B 1 46  ? -17.946 -14.473 25.157  1   19.248 ? 38   ALA B O   1 
ATOM   4352 C  CB  . ALA B 1 46  ? -19.661 -12.715 26.52   1   20.977 ? 38   ALA B CB  1 
ATOM   4353 N  N   . THR B 1 47  ? -19.638 -15.621 24.229  1   17.779 ? 39   THR B N   1 
ATOM   4354 C  CA  . THR B 1 47  ? -18.796 -16.327 23.271  1   18.923 ? 39   THR B CA  1 
ATOM   4355 C  C   . THR B 1 47  ? -18.516 -15.423 22.066  1   19.347 ? 39   THR B C   1 
ATOM   4356 O  O   . THR B 1 47  ? -19.261 -14.469 21.792  1   19.493 ? 39   THR B O   1 
ATOM   4357 C  CB  . THR B 1 47  ? -19.43  -17.629 22.767  1   20.538 ? 39   THR B CB  1 
ATOM   4358 O  OG1 . THR B 1 47  ? -20.522 -17.33  21.884  1   22.293 ? 39   THR B OG1 1 
ATOM   4359 C  CG2 . THR B 1 47  ? -19.798 -18.58  23.9    1   20.391 ? 39   THR B CG2 1 
ATOM   4360 N  N   . ASP B 1 48  ? -17.425 -15.725 21.36   1   17.546 ? 40   ASP B N   1 
ATOM   4361 C  CA  . ASP B 1 48  ? -17.199 -15.264 20      1   17.868 ? 40   ASP B CA  1 
ATOM   4362 C  C   . ASP B 1 48  ? -17.435 -16.453 19.051  1   18.63  ? 40   ASP B C   1 
ATOM   4363 O  O   . ASP B 1 48  ? -17.776 -17.549 19.515  1   19.175 ? 40   ASP B O   1 
ATOM   4364 C  CB  . ASP B 1 48  ? -15.832 -14.58  19.883  1   18.824 ? 40   ASP B CB  1 
ATOM   4365 C  CG  . ASP B 1 48  ? -14.637 -15.491 20.18   1   19.204 ? 40   ASP B CG  1 
ATOM   4366 O  OD1 . ASP B 1 48  ? -14.656 -16.632 19.677  1   18.778 ? 40   ASP B OD1 1 
ATOM   4367 O  OD2 . ASP B 1 48  ? -13.699 -15.056 20.93   1   21.33  ? 40   ASP B OD2 1 
ATOM   4368 N  N   . LEU B 1 49  ? -17.242 -16.254 17.753  1   18.317 ? 41   LEU B N   1 
ATOM   4369 C  CA  . LEU B 1 49  ? -17.591 -17.307 16.788  1   18.843 ? 41   LEU B CA  1 
ATOM   4370 C  C   . LEU B 1 49  ? -16.759 -18.582 16.969  1   19.784 ? 41   LEU B C   1 
ATOM   4371 O  O   . LEU B 1 49  ? -17.188 -19.682 16.599  1   20.968 ? 41   LEU B O   1 
ATOM   4372 C  CB  . LEU B 1 49  ? -17.453 -16.843 15.345  1   18.532 ? 41   LEU B CB  1 
ATOM   4373 C  CG  . LEU B 1 49  ? -18.605 -15.98  14.844  1   19.152 ? 41   LEU B CG  1 
ATOM   4374 C  CD1 . LEU B 1 49  ? -18.179 -15.415 13.508  1   20.449 ? 41   LEU B CD1 1 
ATOM   4375 C  CD2 . LEU B 1 49  ? -19.937 -16.782 14.746  1   21.268 ? 41   LEU B CD2 1 
ATOM   4376 N  N   . SER B 1 50  ? -15.546 -18.443 17.516  1   18.198 ? 42   SER B N   1 
ATOM   4377 C  CA  . SER B 1 50  ? -14.681 -19.578 17.785  1   18.869 ? 42   SER B CA  1 
ATOM   4378 C  C   . SER B 1 50  ? -15.261 -20.474 18.885  1   20.57  ? 42   SER B C   1 
ATOM   4379 O  O   . SER B 1 50  ? -14.789 -21.624 19.006  1   21.014 ? 42   SER B O   1 
ATOM   4380 C  CB  . SER B 1 50  ? -13.253 -19.167 18.12   1   17.958 ? 42   SER B CB  1 
ATOM   4381 O  OG  . SER B 1 50  ? -13.199 -18.709 19.459  1   20.88  ? 42   SER B OG  1 
ATOM   4382 N  N   . GLY B 1 51  ? -16.199 -19.933 19.695  1   19.563 ? 43   GLY B N   1 
ATOM   4383 C  CA  . GLY B 1 51  ? -16.678 -20.604 20.903  1   21.056 ? 43   GLY B CA  1 
ATOM   4384 C  C   . GLY B 1 51  ? -15.947 -20.164 22.176  1   19.333 ? 43   GLY B C   1 
ATOM   4385 O  O   . GLY B 1 51  ? -16.42  -20.439 23.276  1   21.737 ? 43   GLY B O   1 
ATOM   4386 N  N   . GLY B 1 52  ? -14.822 -19.463 22.001  1   18.11  ? 44   GLY B N   1 
ATOM   4387 C  CA  . GLY B 1 52  ? -14.078 -18.891 23.128  1   19.451 ? 44   GLY B CA  1 
ATOM   4388 C  C   . GLY B 1 52  ? -14.948 -17.902 23.9    1   18.227 ? 44   GLY B C   1 
ATOM   4389 O  O   . GLY B 1 52  ? -15.737 -17.188 23.291  1   20.126 ? 44   GLY B O   1 
ATOM   4390 N  N   . ALA B 1 53  ? -14.787 -17.827 25.233  1   19.368 ? 45   ALA B N   1 
ATOM   4391 C  CA  . ALA B 1 53  ? -15.693 -16.961 25.981  1   19.485 ? 45   ALA B CA  1 
ATOM   4392 C  C   . ALA B 1 53  ? -14.913 -16.051 26.932  1   19.338 ? 45   ALA B C   1 
ATOM   4393 O  O   . ALA B 1 53  ? -15.483 -15.637 27.938  1   21.587 ? 45   ALA B O   1 
ATOM   4394 C  CB  . ALA B 1 53  ? -16.793 -17.748 26.694  1   24.213 ? 45   ALA B CB  1 
ATOM   4395 N  N   . GLN B 1 54  ? -13.631 -15.8   26.651  1   18.209 ? 46   GLN B N   1 
ATOM   4396 C  CA  . GLN B 1 54  ? -12.887 -14.945 27.588  1   16.771 ? 46   GLN B CA  1 
ATOM   4397 C  C   . GLN B 1 54  ? -13.007 -13.498 27.099  1   14.399 ? 46   GLN B C   1 
ATOM   4398 O  O   . GLN B 1 54  ? -12.441 -13.155 26.046  1   14.794 ? 46   GLN B O   1 
ATOM   4399 C  CB  . GLN B 1 54  ? -11.409 -15.352 27.707  1   20.553 ? 46   GLN B CB  1 
ATOM   4400 C  CG  . GLN B 1 54  ? -10.534 -14.46  28.599  1   28.996 ? 46   GLN B CG  1 
ATOM   4401 C  CD  . GLN B 1 54  ? -11.027 -14.235 30.022  1   35.753 ? 46   GLN B CD  1 
ATOM   4402 O  OE1 . GLN B 1 54  ? -11.352 -15.203 30.73   1   32.35  ? 46   GLN B OE1 1 
ATOM   4403 N  NE2 . GLN B 1 54  ? -11.064 -12.972 30.471  1   23.311 ? 46   GLN B NE2 1 
ATOM   4404 N  N   . PRO B 1 55  ? -13.612 -12.56  27.867  1   14.55  ? 47   PRO B N   1 
ATOM   4405 C  CA  . PRO B 1 55  ? -13.582 -11.145 27.503  1   14.447 ? 47   PRO B CA  1 
ATOM   4406 C  C   . PRO B 1 55  ? -12.153 -10.607 27.542  1   13.495 ? 47   PRO B C   1 
ATOM   4407 O  O   . PRO B 1 55  ? -11.395 -10.946 28.478  1   14.471 ? 47   PRO B O   1 
ATOM   4408 C  CB  . PRO B 1 55  ? -14.48  -10.428 28.544  1   15.968 ? 47   PRO B CB  1 
ATOM   4409 C  CG  . PRO B 1 55  ? -15.37  -11.586 29.025  1   16.09  ? 47   PRO B CG  1 
ATOM   4410 C  CD  . PRO B 1 55  ? -14.439 -12.783 29.085  1   15.909 ? 47   PRO B CD  1 
ATOM   4411 N  N   . ARG B 1 56  ? -11.812 -9.744  26.572  1   13.359 ? 48   ARG B N   1 
ATOM   4412 C  CA  . ARG B 1 56  ? -10.458 -9.183  26.511  1   13.423 ? 48   ARG B CA  1 
ATOM   4413 C  C   . ARG B 1 56  ? -10.561 -7.683  26.771  1   14.201 ? 48   ARG B C   1 
ATOM   4414 O  O   . ARG B 1 56  ? -10.262 -7.226  27.884  1   14.83  ? 48   ARG B O   1 
ATOM   4415 C  CB  . ARG B 1 56  ? -9.752  -9.532  25.188  1   13.935 ? 48   ARG B CB  1 
ATOM   4416 C  CG  . ARG B 1 56  ? -9.659  -11.033 24.915  1   13.714 ? 48   ARG B CG  1 
ATOM   4417 C  CD  . ARG B 1 56  ? -8.819  -11.777 25.964  1   13.606 ? 48   ARG B CD  1 
ATOM   4418 N  NE  . ARG B 1 56  ? -8.714  -13.186 25.528  1   15.574 ? 48   ARG B NE  1 
ATOM   4419 C  CZ  . ARG B 1 56  ? -8.055  -14.13  26.207  1   16.75  ? 48   ARG B CZ  1 
ATOM   4420 N  NH1 . ARG B 1 56  ? -7.328  -13.814 27.275  1   16.939 ? 48   ARG B NH1 1 
ATOM   4421 N  NH2 . ARG B 1 56  ? -8.083  -15.401 25.767  1   19.6   ? 48   ARG B NH2 1 
ATOM   4422 N  N   . ARG B 1 57  ? -11.01  -6.909  25.774  1   14.782 ? 49   ARG B N   1 
ATOM   4423 C  CA  . ARG B 1 57  ? -11.512 -5.537  25.958  1   15.293 ? 49   ARG B CA  1 
ATOM   4424 C  C   . ARG B 1 57  ? -10.395 -4.513  26.192  1   15.476 ? 49   ARG B C   1 
ATOM   4425 O  O   . ARG B 1 57  ? -10.71  -3.417  26.659  1   16.303 ? 49   ARG B O   1 
ATOM   4426 C  CB  . ARG B 1 57  ? -12.566 -5.418  27.069  1   14.772 ? 49   ARG B CB  1 
ATOM   4427 C  CG  . ARG B 1 57  ? -13.684 -6.455  27.062  1   14.822 ? 49   ARG B CG  1 
ATOM   4428 C  CD  . ARG B 1 57  ? -14.64  -6.414  28.24   1   15.327 ? 49   ARG B CD  1 
ATOM   4429 N  NE  . ARG B 1 57  ? -13.929 -6.577  29.512  1   16.663 ? 49   ARG B NE  1 
ATOM   4430 C  CZ  . ARG B 1 57  ? -14.151 -5.927  30.64   1   13.516 ? 49   ARG B CZ  1 
ATOM   4431 N  NH1 . ARG B 1 57  ? -15.134 -5.052  30.781  1   14.32  ? 49   ARG B NH1 1 
ATOM   4432 N  NH2 . ARG B 1 57  ? -13.365 -6.244  31.67   1   14.42  ? 49   ARG B NH2 1 
ATOM   4433 N  N   . PHE B 1 58  ? -9.16   -4.848  25.816  1   16.439 ? 50   PHE B N   1 
ATOM   4434 C  CA  . PHE B 1 58  ? -8.052  -3.894  25.976  1   15.116 ? 50   PHE B CA  1 
ATOM   4435 C  C   . PHE B 1 58  ? -8.193  -2.832  24.9    1   14.463 ? 50   PHE B C   1 
ATOM   4436 O  O   . PHE B 1 58  ? -8.463  -3.118  23.733  1   14.311 ? 50   PHE B O   1 
ATOM   4437 C  CB  . PHE B 1 58  ? -6.71   -4.643  25.738  1   19.83  ? 50   PHE B CB  1 
ATOM   4438 C  CG  . PHE B 1 58  ? -5.453  -3.767  25.915  1   17.659 ? 50   PHE B CG  1 
ATOM   4439 C  CD1 . PHE B 1 58  ? -5.089  -3.319  27.201  1   19.776 ? 50   PHE B CD1 1 
ATOM   4440 C  CD2 . PHE B 1 58  ? -4.625  -3.419  24.833  1   19.45  ? 50   PHE B CD2 1 
ATOM   4441 C  CE1 . PHE B 1 58  ? -3.914  -2.553  27.403  1   18.359 ? 50   PHE B CE1 1 
ATOM   4442 C  CE2 . PHE B 1 58  ? -3.446  -2.666  25.055  1   16.754 ? 50   PHE B CE2 1 
ATOM   4443 C  CZ  . PHE B 1 58  ? -3.183  -2.191  26.304  1   18.84  ? 50   PHE B CZ  1 
ATOM   4444 N  N   . GLU B 1 59  ? -7.838  -1.6    25.292  1   12.896 ? 51   GLU B N   1 
ATOM   4445 C  CA  . GLU B 1 59  ? -7.715  -0.493  24.35   1   11.833 ? 51   GLU B CA  1 
ATOM   4446 C  C   . GLU B 1 59  ? -6.315  0.087   24.537  1   12.804 ? 51   GLU B C   1 
ATOM   4447 O  O   . GLU B 1 59  ? -6.034  0.636   25.624  1   12.964 ? 51   GLU B O   1 
ATOM   4448 C  CB  . GLU B 1 59  ? -8.82   0.545   24.586  1   12.073 ? 51   GLU B CB  1 
ATOM   4449 C  CG  . GLU B 1 59  ? -10.225 -0.017  24.422  1   13.889 ? 51   GLU B CG  1 
ATOM   4450 C  CD  . GLU B 1 59  ? -11.196 1.15    24.405  1   14.3   ? 51   GLU B CD  1 
ATOM   4451 O  OE1 . GLU B 1 59  ? -11.422 1.752   25.478  1   14.327 ? 51   GLU B OE1 1 
ATOM   4452 O  OE2 . GLU B 1 59  ? -11.686 1.482   23.29   1   13.134 ? 51   GLU B OE2 1 
ATOM   4453 N  N   . GLY B 1 60  ? -5.47   0.018   23.509  1   13.052 ? 52   GLY B N   1 
ATOM   4454 C  CA  . GLY B 1 60  ? -4.165  0.665   23.642  1   12.693 ? 52   GLY B CA  1 
ATOM   4455 C  C   . GLY B 1 60  ? -3.193  0.139   22.6    1   14.046 ? 52   GLY B C   1 
ATOM   4456 O  O   . GLY B 1 60  ? -3.631  -0.376  21.56   1   14.502 ? 52   GLY B O   1 
ATOM   4457 N  N   . THR B 1 61  ? -1.896  0.22    22.932  1   13.488 ? 53   THR B N   1 
ATOM   4458 C  CA  . THR B 1 61  ? -0.873  0.017   21.894  1   12.879 ? 53   THR B CA  1 
ATOM   4459 C  C   . THR B 1 61  ? 0.274   -0.834  22.394  1   13.176 ? 53   THR B C   1 
ATOM   4460 O  O   . THR B 1 61  ? 0.545   -0.903  23.588  1   14.948 ? 53   THR B O   1 
ATOM   4461 C  CB  . THR B 1 61  ? -0.338  1.365   21.406  1   13.343 ? 53   THR B CB  1 
ATOM   4462 O  OG1 . THR B 1 61  ? 0.242   2.093   22.487  1   14.637 ? 53   THR B OG1 1 
ATOM   4463 C  CG2 . THR B 1 61  ? -1.4    2.212   20.715  1   15.025 ? 53   THR B CG2 1 
ATOM   4464 N  N   . ILE B 1 62  ? 1.016   -1.392  21.415  1   13.843 ? 54   ILE B N   1 
ATOM   4465 C  CA  . ILE B 1 62  ? 2.373   -1.879  21.654  1   14.123 ? 54   ILE B CA  1 
ATOM   4466 C  C   . ILE B 1 62  ? 3.219   -1.333  20.512  1   14.703 ? 54   ILE B C   1 
ATOM   4467 O  O   . ILE B 1 62  ? 2.881   -1.554  19.339  1   16.396 ? 54   ILE B O   1 
ATOM   4468 C  CB  . ILE B 1 62  ? 2.453   -3.413  21.652  1   13.806 ? 54   ILE B CB  1 
ATOM   4469 C  CG1 . ILE B 1 62  ? 1.629   -4.002  22.78   1   16.784 ? 54   ILE B CG1 1 
ATOM   4470 C  CG2 . ILE B 1 62  ? 3.919   -3.882  21.749  1   14.97  ? 54   ILE B CG2 1 
ATOM   4471 C  CD1 . ILE B 1 62  ? 1.339   -5.472  22.616  1   20.392 ? 54   ILE B CD1 1 
ATOM   4472 N  N   . PHE B 1 63  ? 4.304   -0.613  20.858  1   14.473 ? 55   PHE B N   1 
ATOM   4473 C  CA  . PHE B 1 63  ? 5.231   -0.108  19.85   1   15.215 ? 55   PHE B CA  1 
ATOM   4474 C  C   . PHE B 1 63  ? 6.304   -1.172  19.609  1   14.743 ? 55   PHE B C   1 
ATOM   4475 O  O   . PHE B 1 63  ? 6.868   -1.677  20.57   1   14.175 ? 55   PHE B O   1 
ATOM   4476 C  CB  . PHE B 1 63  ? 5.85    1.198   20.371  1   15.087 ? 55   PHE B CB  1 
ATOM   4477 C  CG  . PHE B 1 63  ? 6.872   1.798   19.43   1   16.03  ? 55   PHE B CG  1 
ATOM   4478 C  CD1 . PHE B 1 63  ? 6.479   2.649   18.383  1   16.703 ? 55   PHE B CD1 1 
ATOM   4479 C  CD2 . PHE B 1 63  ? 8.24    1.552   19.636  1   16.38  ? 55   PHE B CD2 1 
ATOM   4480 C  CE1 . PHE B 1 63  ? 7.401   3.233   17.522  1   19.201 ? 55   PHE B CE1 1 
ATOM   4481 C  CE2 . PHE B 1 63  ? 9.182   2.139   18.79   1   17.79  ? 55   PHE B CE2 1 
ATOM   4482 C  CZ  . PHE B 1 63  ? 8.766   2.99    17.727  1   17.705 ? 55   PHE B CZ  1 
ATOM   4483 N  N   . ASP B 1 64  ? 6.548   -1.529  18.33   1   15.284 ? 56   ASP B N   1 
ATOM   4484 C  CA  . ASP B 1 64  ? 7.608   -2.498  17.981  1   14.93  ? 56   ASP B CA  1 
ATOM   4485 C  C   . ASP B 1 64  ? 7.305   -3.851  18.631  1   14.199 ? 56   ASP B C   1 
ATOM   4486 O  O   . ASP B 1 64  ? 8.038   -4.352  19.513  1   15.352 ? 56   ASP B O   1 
ATOM   4487 C  CB  . ASP B 1 64  ? 8.984   -1.947  18.368  1   15.856 ? 56   ASP B CB  1 
ATOM   4488 C  CG  . ASP B 1 64  ? 10.121  -2.531  17.547  1   17.032 ? 56   ASP B CG  1 
ATOM   4489 O  OD1 . ASP B 1 64  ? 9.889   -3.391  16.696  1   19.002 ? 56   ASP B OD1 1 
ATOM   4490 O  OD2 . ASP B 1 64  ? 11.279  -2.141  17.802  1   17.589 ? 56   ASP B OD2 1 
ATOM   4491 N  N   . VAL B 1 65  ? 6.175   -4.445  18.188  1   14.406 ? 57   VAL B N   1 
ATOM   4492 C  CA  . VAL B 1 65  ? 5.72    -5.735  18.698  1   13.933 ? 57   VAL B CA  1 
ATOM   4493 C  C   . VAL B 1 65  ? 6.833   -6.771  18.455  1   13.892 ? 57   VAL B C   1 
ATOM   4494 O  O   . VAL B 1 65  ? 7.467   -6.736  17.381  1   15.948 ? 57   VAL B O   1 
ATOM   4495 C  CB  . VAL B 1 65  ? 4.408   -6.163  17.974  1   14.717 ? 57   VAL B CB  1 
ATOM   4496 C  CG1 . VAL B 1 65  ? 3.87    -7.467  18.566  1   16.494 ? 57   VAL B CG1 1 
ATOM   4497 C  CG2 . VAL B 1 65  ? 3.341   -5.086  18.1    1   14.728 ? 57   VAL B CG2 1 
ATOM   4498 N  N   . MET B 1 66  ? 7.047   -7.68   19.415  1   15.536 ? 58   MET B N   1 
ATOM   4499 C  CA  . MET B 1 66  ? 8.031   -8.759  19.261  1   15.771 ? 58   MET B CA  1 
ATOM   4500 C  C   . MET B 1 66  ? 7.72    -9.55   18.001  1   16.461 ? 58   MET B C   1 
ATOM   4501 O  O   . MET B 1 66  ? 6.55    -9.85   17.713  1   16.746 ? 58   MET B O   1 
ATOM   4502 C  CB  . MET B 1 66  ? 7.928   -9.721  20.45   1   20.041 ? 58   MET B CB  1 
ATOM   4503 C  CG  . MET B 1 66  ? 9.192   -10.514 20.718  1   34.767 ? 58   MET B CG  1 
ATOM   4504 S  SD  . MET B 1 66  ? 9.208   -11.387 22.304  1   51.224 ? 58   MET B SD  1 
ATOM   4505 C  CE  . MET B 1 66  ? 8.349   -10.108 23.203  1   13.979 ? 58   MET B CE  1 
ATOM   4506 N  N   . THR B 1 67  ? 8.793   -9.901  17.281  1   17.927 ? 59   THR B N   1 
ATOM   4507 C  CA  . THR B 1 67  ? 8.641   -10.729 16.087  1   18.525 ? 59   THR B CA  1 
ATOM   4508 C  C   . THR B 1 67  ? 9.62    -11.893 16.115  1   21.401 ? 59   THR B C   1 
ATOM   4509 O  O   . THR B 1 67  ? 10.694  -11.806 16.722  1   22.678 ? 59   THR B O   1 
ATOM   4510 C  CB  . THR B 1 67  ? 8.819   -9.91   14.806  1   21.299 ? 59   THR B CB  1 
ATOM   4511 O  OG1 . THR B 1 67  ? 10.127  -9.328  14.768  1   23.19  ? 59   THR B OG1 1 
ATOM   4512 C  CG2 . THR B 1 67  ? 7.761   -8.827  14.618  1   19.826 ? 59   THR B CG2 1 
ATOM   4513 N  N   . ARG B 1 68  ? 9.213   -12.981 15.476  1   19.472 ? 60   ARG B N   1 
ATOM   4514 C  CA  . ARG B 1 68  ? 10.095  -14.117 15.244  1   20.245 ? 60   ARG B CA  1 
ATOM   4515 C  C   . ARG B 1 68  ? 10.237  -14.303 13.755  1   20.261 ? 60   ARG B C   1 
ATOM   4516 O  O   . ARG B 1 68  ? 9.278   -14.179 13.017  1   21.595 ? 60   ARG B O   1 
ATOM   4517 C  CB  . ARG B 1 68  ? 9.543   -15.38  15.871  1   21.549 ? 60   ARG B CB  1 
ATOM   4518 C  CG  . ARG B 1 68  ? 9.34    -15.299 17.378  1   24.478 ? 60   ARG B CG  1 
ATOM   4519 C  CD  . ARG B 1 68  ? 8.961   -16.664 18.005  1   24.543 ? 60   ARG B CD  1 
ATOM   4520 N  NE  . ARG B 1 68  ? 7.825   -17.32  17.318  1   26.576 ? 60   ARG B NE  1 
ATOM   4521 C  CZ  . ARG B 1 68  ? 6.524   -17.235 17.652  1   28.241 ? 60   ARG B CZ  1 
ATOM   4522 N  NH1 . ARG B 1 68  ? 6.106   -16.304 18.527  1   25.789 ? 60   ARG B NH1 1 
ATOM   4523 N  NH2 . ARG B 1 68  ? 5.632   -18.037 17.063  1   23.238 ? 60   ARG B NH2 1 
ATOM   4524 N  N   . GLY B 1 69  ? 11.477  -14.495 13.309  1   22.464 ? 61   GLY B N   1 
ATOM   4525 C  CA  . GLY B 1 69  ? 11.68   -14.551 11.869  1   24.023 ? 61   GLY B CA  1 
ATOM   4526 C  C   . GLY B 1 69  ? 11.929  -13.159 11.322  1   27.352 ? 61   GLY B C   1 
ATOM   4527 O  O   . GLY B 1 69  ? 12.205  -12.237 12.08   1   32.371 ? 61   GLY B O   1 
ATOM   4528 N  N   . THR B 1 70  ? 11.859  -13.005 10.002  1   31.504 ? 62   THR B N   1 
ATOM   4529 C  CA  . THR B 1 70  ? 12.116  -11.722 9.362   1   28.615 ? 62   THR B CA  1 
ATOM   4530 C  C   . THR B 1 70  ? 10.82   -11.229 8.73    1   24.525 ? 62   THR B C   1 
ATOM   4531 O  O   . THR B 1 70  ? 10.241  -11.916 7.903   1   25.532 ? 62   THR B O   1 
ATOM   4532 C  CB  . THR B 1 70  ? 13.238  -11.848 8.325   1   35.565 ? 62   THR B CB  1 
ATOM   4533 O  OG1 . THR B 1 70  ? 14.411  -12.2   9.052   1   40.917 ? 62   THR B OG1 1 
ATOM   4534 C  CG2 . THR B 1 70  ? 13.583  -10.524 7.669   1   35.234 ? 62   THR B CG2 1 
ATOM   4535 N  N   . ILE B 1 71  ? 10.383  -10.042 9.153   1   24.428 ? 63   ILE B N   1 
ATOM   4536 C  CA  . ILE B 1 71  ? 9.202   -9.418  8.583   1   23.151 ? 63   ILE B CA  1 
ATOM   4537 C  C   . ILE B 1 71  ? 9.538   -9      7.155   1   20.865 ? 63   ILE B C   1 
ATOM   4538 O  O   . ILE B 1 71  ? 10.497  -8.262  6.948   1   23.199 ? 63   ILE B O   1 
ATOM   4539 C  CB  . ILE B 1 71  ? 8.714   -8.227  9.437   1   25.032 ? 63   ILE B CB  1 
ATOM   4540 C  CG1 . ILE B 1 71  ? 8.346   -8.713  10.871  1   22.783 ? 63   ILE B CG1 1 
ATOM   4541 C  CG2 . ILE B 1 71  ? 7.59    -7.456  8.728   1   22.773 ? 63   ILE B CG2 1 
ATOM   4542 C  CD1 . ILE B 1 71  ? 7.087   -9.58   10.973  1   22.803 ? 63   ILE B CD1 1 
ATOM   4543 N  N   . PRO B 1 72  ? 8.775   -9.452  6.124   1   21.107 ? 64   PRO B N   1 
ATOM   4544 C  CA  . PRO B 1 72  ? 9.085   -9.111  4.737   1   22.246 ? 64   PRO B CA  1 
ATOM   4545 C  C   . PRO B 1 72  ? 9.125   -7.605  4.543   1   24.133 ? 64   PRO B C   1 
ATOM   4546 O  O   . PRO B 1 72  ? 8.225   -6.874  5.005   1   22.207 ? 64   PRO B O   1 
ATOM   4547 C  CB  . PRO B 1 72  ? 7.935   -9.765  3.947   1   20.663 ? 64   PRO B CB  1 
ATOM   4548 C  CG  . PRO B 1 72  ? 7.549   -10.98  4.779   1   21.979 ? 64   PRO B CG  1 
ATOM   4549 C  CD  . PRO B 1 72  ? 7.68    -10.443 6.208   1   22.425 ? 64   PRO B CD  1 
ATOM   4550 N  N   . LYS B 1 73  ? 10.172  -7.132  3.859   1   24.408 ? 65   LYS B N   1 
ATOM   4551 C  CA  . LYS B 1 73  ? 10.294  -5.717  3.557   1   24.624 ? 65   LYS B CA  1 
ATOM   4552 C  C   . LYS B 1 73  ? 9.174   -5.21   2.636   1   22.174 ? 65   LYS B C   1 
ATOM   4553 O  O   . LYS B 1 73  ? 8.86    -4.022  2.603   1   22.24  ? 65   LYS B O   1 
ATOM   4554 C  CB  . LYS B 1 73  ? 11.715  -5.355  3.103   1   31.717 ? 65   LYS B CB  1 
ATOM   4555 C  CG  . LYS B 1 73  ? 12.674  -5.152  4.308   1   43.428 ? 65   LYS B CG  1 
ATOM   4556 C  CD  . LYS B 1 73  ? 12.358  -4.133  5.431   1   42.669 ? 65   LYS B CD  1 
ATOM   4557 C  CE  . LYS B 1 73  ? 13.477  -3.994  6.434   1   51.494 ? 65   LYS B CE  1 
ATOM   4558 N  NZ  . LYS B 1 73  ? 14.794  -3.685  5.863   1   60.364 ? 65   LYS B NZ  1 
ATOM   4559 N  N   . GLU B 1 74  ? 8.54    -6.141  1.921   1   23.139 ? 66   GLU B N   1 
ATOM   4560 C  CA  . GLU B 1 74  ? 7.506   -5.774  0.962   1   23.266 ? 66   GLU B CA  1 
ATOM   4561 C  C   . GLU B 1 74  ? 6.173   -5.436  1.643   1   22.634 ? 66   GLU B C   1 
ATOM   4562 O  O   . GLU B 1 74  ? 5.27    -4.929  0.98    1   23.333 ? 66   GLU B O   1 
ATOM   4563 C  CB  . GLU B 1 74  ? 7.242   -6.937  0.01    1   23.081 ? 66   GLU B CB  1 
ATOM   4564 C  CG  . GLU B 1 74  ? 8.436   -7.237  -0.914  1   24.536 ? 66   GLU B CG  1 
ATOM   4565 C  CD  . GLU B 1 74  ? 9.402   -8.287  -0.365  1   29.866 ? 66   GLU B CD  1 
ATOM   4566 O  OE1 . GLU B 1 74  ? 9.332   -8.662  0.833   1   25.972 ? 66   GLU B OE1 1 
ATOM   4567 O  OE2 . GLU B 1 74  ? 10.239  -8.83   -1.155  1   29.694 ? 66   GLU B OE2 1 
ATOM   4568 N  N   . LEU B 1 75  ? 6.029   -5.758  2.943   1   20.257 ? 67   LEU B N   1 
ATOM   4569 C  CA  . LEU B 1 75  ? 4.803   -5.375  3.648   1   18.058 ? 67   LEU B CA  1 
ATOM   4570 C  C   . LEU B 1 75  ? 4.842   -3.903  4.018   1   18.465 ? 67   LEU B C   1 
ATOM   4571 O  O   . LEU B 1 75  ? 5.763   -3.47   4.733   1   21.042 ? 67   LEU B O   1 
ATOM   4572 C  CB  . LEU B 1 75  ? 4.61    -6.237  4.891   1   17.281 ? 67   LEU B CB  1 
ATOM   4573 C  CG  . LEU B 1 75  ? 4.274   -7.698  4.574   1   19.555 ? 67   LEU B CG  1 
ATOM   4574 C  CD1 . LEU B 1 75  ? 4.236   -8.436  5.897   1   20.112 ? 67   LEU B CD1 1 
ATOM   4575 C  CD2 . LEU B 1 75  ? 2.934   -7.81   3.842   1   22.23  ? 67   LEU B CD2 1 
ATOM   4576 N  N   . HIS B 1 76  ? 3.859   -3.149  3.525   1   17.772 ? 68   HIS B N   1 
ATOM   4577 C  CA  . HIS B 1 76  ? 3.823   -1.691  3.695   1   17.016 ? 68   HIS B CA  1 
ATOM   4578 C  C   . HIS B 1 76  ? 2.36    -1.319  3.805   1   17.803 ? 68   HIS B C   1 
ATOM   4579 O  O   . HIS B 1 76  ? 1.696   -0.982  2.834   1   18.88  ? 68   HIS B O   1 
ATOM   4580 C  CB  . HIS B 1 76  ? 4.489   -0.969  2.5     1   17.628 ? 68   HIS B CB  1 
ATOM   4581 C  CG  . HIS B 1 76  ? 4.823   0.466   2.741   1   18.755 ? 68   HIS B CG  1 
ATOM   4582 N  ND1 . HIS B 1 76  ? 5.833   0.899   3.6     1   19.872 ? 68   HIS B ND1 1 
ATOM   4583 C  CD2 . HIS B 1 76  ? 4.256   1.568   2.303   1   18.696 ? 68   HIS B CD2 1 
ATOM   4584 C  CE1 . HIS B 1 76  ? 5.861   2.219   3.61    1   20.074 ? 68   HIS B CE1 1 
ATOM   4585 N  NE2 . HIS B 1 76  ? 4.889   2.65    2.86    1   21.209 ? 68   HIS B NE2 1 
ATOM   4586 N  N   . GLY B 1 77  ? 1.82    -1.45   5.029   1   16.687 ? 69   GLY B N   1 
ATOM   4587 C  CA  . GLY B 1 77  ? 0.39    -1.272  5.182   1   18.14  ? 69   GLY B CA  1 
ATOM   4588 C  C   . GLY B 1 77  ? -0.047  -1.766  6.564   1   16.776 ? 69   GLY B C   1 
ATOM   4589 O  O   . GLY B 1 77  ? 0.773   -1.878  7.463   1   16.182 ? 69   GLY B O   1 
ATOM   4590 N  N   . THR B 1 78  ? -1.361  -1.974  6.712   1   16.835 ? 70   THR B N   1 
ATOM   4591 C  CA  . THR B 1 78  ? -1.937  -2.303  8.024   1   15.812 ? 70   THR B CA  1 
ATOM   4592 C  C   . THR B 1 78  ? -2.886  -3.47   7.843   1   15.857 ? 70   THR B C   1 
ATOM   4593 O  O   . THR B 1 78  ? -3.756  -3.417  6.974   1   16.498 ? 70   THR B O   1 
ATOM   4594 C  CB  . THR B 1 78  ? -2.662  -1.11   8.63    1   16.807 ? 70   THR B CB  1 
ATOM   4595 O  OG1 . THR B 1 78  ? -1.881  0.072   8.487   1   17.419 ? 70   THR B OG1 1 
ATOM   4596 C  CG2 . THR B 1 78  ? -2.948  -1.325  10.117  1   15.253 ? 70   THR B CG2 1 
ATOM   4597 N  N   . PHE B 1 79  ? -2.766  -4.453  8.727   1   15.29  ? 71   PHE B N   1 
ATOM   4598 C  CA  . PHE B 1 79  ? -3.752  -5.514  8.843   1   14.863 ? 71   PHE B CA  1 
ATOM   4599 C  C   . PHE B 1 79  ? -4.705  -5.085  9.947   1   15.832 ? 71   PHE B C   1 
ATOM   4600 O  O   . PHE B 1 79  ? -4.314  -4.999  11.11   1   14.794 ? 71   PHE B O   1 
ATOM   4601 C  CB  . PHE B 1 79  ? -3.048  -6.811  9.215   1   16.482 ? 71   PHE B CB  1 
ATOM   4602 C  CG  . PHE B 1 79  ? -3.92   -8.054  9.374   1   15.981 ? 71   PHE B CG  1 
ATOM   4603 C  CD1 . PHE B 1 79  ? -5.238  -8.132  8.858   1   15.667 ? 71   PHE B CD1 1 
ATOM   4604 C  CD2 . PHE B 1 79  ? -3.36   -9.156  10.001  1   18.046 ? 71   PHE B CD2 1 
ATOM   4605 C  CE1 . PHE B 1 79  ? -5.987  -9.305  9.034   1   16.968 ? 71   PHE B CE1 1 
ATOM   4606 C  CE2 . PHE B 1 79  ? -4.082  -10.343 10.153  1   19.261 ? 71   PHE B CE2 1 
ATOM   4607 C  CZ  . PHE B 1 79  ? -5.396  -10.419 9.635   1   17.806 ? 71   PHE B CZ  1 
ATOM   4608 N  N   . TYR B 1 80  ? -5.934  -4.745  9.542   1   15.175 ? 72   TYR B N   1 
ATOM   4609 C  CA  . TYR B 1 80  ? -6.981  -4.332  10.487  1   14.744 ? 72   TYR B CA  1 
ATOM   4610 C  C   . TYR B 1 80  ? -7.906  -5.517  10.686  1   18.035 ? 72   TYR B C   1 
ATOM   4611 O  O   . TYR B 1 80  ? -8.474  -6.021  9.718   1   17.059 ? 72   TYR B O   1 
ATOM   4612 C  CB  . TYR B 1 80  ? -7.813  -3.16   9.992   1   17.035 ? 72   TYR B CB  1 
ATOM   4613 C  CG  . TYR B 1 80  ? -7.067  -1.832  9.919   1   15.377 ? 72   TYR B CG  1 
ATOM   4614 C  CD1 . TYR B 1 80  ? -6.962  -0.951  11.012  1   15.051 ? 72   TYR B CD1 1 
ATOM   4615 C  CD2 . TYR B 1 80  ? -6.543  -1.397  8.699   1   16.857 ? 72   TYR B CD2 1 
ATOM   4616 C  CE1 . TYR B 1 80  ? -6.369  0.299   10.881  1   17.414 ? 72   TYR B CE1 1 
ATOM   4617 C  CE2 . TYR B 1 80  ? -5.959  -0.138  8.564   1   16.561 ? 72   TYR B CE2 1 
ATOM   4618 C  CZ  . TYR B 1 80  ? -5.816  0.696   9.663   1   16.323 ? 72   TYR B CZ  1 
ATOM   4619 O  OH  . TYR B 1 80  ? -5.257  1.935   9.516   1   17.555 ? 72   TYR B OH  1 
ATOM   4620 N  N   . ARG B 1 81  ? -8.092  -5.981  11.935  1   15.832 ? 73   ARG B N   1 
ATOM   4621 C  CA  . ARG B 1 81  ? -9.01   -7.082  12.19   1   15.047 ? 73   ARG B CA  1 
ATOM   4622 C  C   . ARG B 1 81  ? -10.08  -6.584  13.149  1   15.758 ? 73   ARG B C   1 
ATOM   4623 O  O   . ARG B 1 81  ? -9.773  -5.752  14.009  1   17.142 ? 73   ARG B O   1 
ATOM   4624 C  CB  . ARG B 1 81  ? -8.255  -8.126  13.016  1   19.246 ? 73   ARG B CB  1 
ATOM   4625 C  CG  . ARG B 1 81  ? -7.441  -9.267  12.42   1   26.243 ? 73   ARG B CG  1 
ATOM   4626 C  CD  . ARG B 1 81  ? -8.312  -10.419 11.798  1   19.315 ? 73   ARG B CD  1 
ATOM   4627 N  NE  . ARG B 1 81  ? -9.023  -11.452 12.554  1   19.174 ? 73   ARG B NE  1 
ATOM   4628 C  CZ  . ARG B 1 81  ? -10.076 -12.122 12.04   1   17.941 ? 73   ARG B CZ  1 
ATOM   4629 N  NH1 . ARG B 1 81  ? -10.474 -11.892 10.781  1   17.788 ? 73   ARG B NH1 1 
ATOM   4630 N  NH2 . ARG B 1 81  ? -10.754 -12.968 12.801  1   17.74  ? 73   ARG B NH2 1 
ATOM   4631 N  N   . ILE B 1 82  ? -11.32  -7.046  12.973  1   14.244 ? 74   ILE B N   1 
ATOM   4632 C  CA  . ILE B 1 82  ? -12.375 -6.609  13.877  1   13.504 ? 74   ILE B CA  1 
ATOM   4633 C  C   . ILE B 1 82  ? -12.994 -7.804  14.59   1   15.453 ? 74   ILE B C   1 
ATOM   4634 O  O   . ILE B 1 82  ? -13.066 -8.914  14.048  1   15.735 ? 74   ILE B O   1 
ATOM   4635 C  CB  . ILE B 1 82  ? -13.417 -5.76   13.122  1   12.951 ? 74   ILE B CB  1 
ATOM   4636 C  CG1 . ILE B 1 82  ? -14.282 -4.896  14.082  1   15.739 ? 74   ILE B CG1 1 
ATOM   4637 C  CG2 . ILE B 1 82  ? -14.284 -6.564  12.139  1   14.035 ? 74   ILE B CG2 1 
ATOM   4638 C  CD1 . ILE B 1 82  ? -15.013 -3.79   13.337  1   14.442 ? 74   ILE B CD1 1 
ATOM   4639 N  N   . MET B 1 83  ? -13.345 -7.565  15.858  1   13.904 ? 75   MET B N   1 
ATOM   4640 C  CA  . MET B 1 83  ? -13.792 -8.633  16.731  1   14.375 ? 75   MET B CA  1 
ATOM   4641 C  C   . MET B 1 83  ? -14.983 -8.188  17.55   1   12.797 ? 75   MET B C   1 
ATOM   4642 O  O   . MET B 1 83  ? -15.121 -7.023  17.915  1   14.098 ? 75   MET B O   1 
ATOM   4643 C  CB  . MET B 1 83  ? -12.708 -9.018  17.75   1   14.167 ? 75   MET B CB  1 
ATOM   4644 C  CG  . MET B 1 83  ? -11.414 -9.589  17.133  1   13.814 ? 75   MET B CG  1 
ATOM   4645 S  SD  . MET B 1 83  ? -9.91   -8.987  17.954  1   17.303 ? 75   MET B SD  1 
ATOM   4646 C  CE  . MET B 1 83  ? -9.842  -7.42   17.122  1   17.924 ? 75   MET B CE  1 
ATOM   4647 N  N   . PRO B 1 84  ? -15.893 -9.121  17.902  1   13.275 ? 76   PRO B N   1 
ATOM   4648 C  CA  . PRO B 1 84  ? -16.921 -8.862  18.895  1   14.33  ? 76   PRO B CA  1 
ATOM   4649 C  C   . PRO B 1 84  ? -16.354 -9.069  20.295  1   14.642 ? 76   PRO B C   1 
ATOM   4650 O  O   . PRO B 1 84  ? -15.817 -10.125 20.58   1   15.396 ? 76   PRO B O   1 
ATOM   4651 C  CB  . PRO B 1 84  ? -18.02  -9.895  18.52   1   13.838 ? 76   PRO B CB  1 
ATOM   4652 C  CG  . PRO B 1 84  ? -17.203 -11.137 18.072  1   17.156 ? 76   PRO B CG  1 
ATOM   4653 C  CD  . PRO B 1 84  ? -15.934 -10.518 17.377  1   15.872 ? 76   PRO B CD  1 
ATOM   4654 N  N   . ASP B 1 85  ? -16.444 -8.047  21.146  1   12.536 ? 77   ASP B N   1 
ATOM   4655 C  CA  . ASP B 1 85  ? -15.851 -8.153  22.487  1   13.598 ? 77   ASP B CA  1 
ATOM   4656 C  C   . ASP B 1 85  ? -16.698 -7.279  23.398  1   13.182 ? 77   ASP B C   1 
ATOM   4657 O  O   . ASP B 1 85  ? -16.272 -6.174  23.744  1   14.004 ? 77   ASP B O   1 
ATOM   4658 C  CB  . ASP B 1 85  ? -14.398 -7.701  22.437  1   13.942 ? 77   ASP B CB  1 
ATOM   4659 C  CG  . ASP B 1 85  ? -13.461 -8.173  23.56   1   15.077 ? 77   ASP B CG  1 
ATOM   4660 O  OD1 . ASP B 1 85  ? -13.871 -9.02   24.404  1   15.141 ? 77   ASP B OD1 1 
ATOM   4661 O  OD2 . ASP B 1 85  ? -12.249 -7.759  23.477  1   15.979 ? 77   ASP B OD2 1 
ATOM   4662 N  N   . TYR B 1 86  ? -17.857 -7.796  23.834  1   12.826 ? 78   TYR B N   1 
ATOM   4663 C  CA  . TYR B 1 86  ? -18.727 -6.988  24.67   1   13.441 ? 78   TYR B CA  1 
ATOM   4664 C  C   . TYR B 1 86  ? -17.939 -6.226  25.734  1   14.453 ? 78   TYR B C   1 
ATOM   4665 O  O   . TYR B 1 86  ? -17.152 -6.803  26.513  1   14.021 ? 78   TYR B O   1 
ATOM   4666 C  CB  . TYR B 1 86  ? -19.671 -7.942  25.396  1   14.263 ? 78   TYR B CB  1 
ATOM   4667 C  CG  . TYR B 1 86  ? -21.008 -8.176  24.717  1   13.391 ? 78   TYR B CG  1 
ATOM   4668 C  CD1 . TYR B 1 86  ? -21.906 -7.12   24.579  1   15.249 ? 78   TYR B CD1 1 
ATOM   4669 C  CD2 . TYR B 1 86  ? -21.385 -9.459  24.343  1   13.479 ? 78   TYR B CD2 1 
ATOM   4670 C  CE1 . TYR B 1 86  ? -23.181 -7.345  24.036  1   13.307 ? 78   TYR B CE1 1 
ATOM   4671 C  CE2 . TYR B 1 86  ? -22.657 -9.688  23.813  1   14.62  ? 78   TYR B CE2 1 
ATOM   4672 C  CZ  . TYR B 1 86  ? -23.549 -8.637  23.699  1   14.465 ? 78   TYR B CZ  1 
ATOM   4673 O  OH  . TYR B 1 86  ? -24.848 -8.86   23.291  1   15.658 ? 78   TYR B OH  1 
ATOM   4674 N  N   . ALA B 1 87  ? -18.146 -4.899  25.735  1   13.214 ? 79   ALA B N   1 
ATOM   4675 C  CA  . ALA B 1 87  ? -17.336 -4.042  26.61   1   13.62  ? 79   ALA B CA  1 
ATOM   4676 C  C   . ALA B 1 87  ? -17.847 -4.045  28.046  1   12.897 ? 79   ALA B C   1 
ATOM   4677 O  O   . ALA B 1 87  ? -17.058 -3.894  28.999  1   13.895 ? 79   ALA B O   1 
ATOM   4678 C  CB  . ALA B 1 87  ? -17.298 -2.619  26.055  1   12.657 ? 79   ALA B CB  1 
ATOM   4679 N  N   . GLN B 1 88  ? -19.163 -4.203  28.203  1   14.214 ? 80   GLN B N   1 
ATOM   4680 C  CA  . GLN B 1 88  ? -19.776 -4.426  29.498  1   14.009 ? 80   GLN B CA  1 
ATOM   4681 C  C   . GLN B 1 88  ? -20.499 -5.764  29.518  1   14.373 ? 80   GLN B C   1 
ATOM   4682 O  O   . GLN B 1 88  ? -20.895 -6.285  28.462  1   14.198 ? 80   GLN B O   1 
ATOM   4683 C  CB  . GLN B 1 88  ? -20.869 -3.39   29.749  1   14.045 ? 80   GLN B CB  1 
ATOM   4684 C  CG  . GLN B 1 88  ? -20.374 -1.94   29.782  1   14.434 ? 80   GLN B CG  1 
ATOM   4685 C  CD  . GLN B 1 88  ? -19.409 -1.747  30.94   1   13.57  ? 80   GLN B CD  1 
ATOM   4686 O  OE1 . GLN B 1 88  ? -19.629 -2.16   32.098  1   15.973 ? 80   GLN B OE1 1 
ATOM   4687 N  NE2 . GLN B 1 88  ? -18.31  -1.107  30.681  1   13.866 ? 80   GLN B NE2 1 
ATOM   4688 N  N   . PRO B 1 89  ? -20.64  -6.412  30.692  1   14.374 ? 81   PRO B N   1 
ATOM   4689 C  CA  . PRO B 1 89  ? -21.324 -7.697  30.735  1   14.324 ? 81   PRO B CA  1 
ATOM   4690 C  C   . PRO B 1 89  ? -22.76  -7.531  30.227  1   13.83  ? 81   PRO B C   1 
ATOM   4691 O  O   . PRO B 1 89  ? -23.46  -6.67   30.737  1   14.031 ? 81   PRO B O   1 
ATOM   4692 C  CB  . PRO B 1 89  ? -21.281 -8.102  32.235  1   14.369 ? 81   PRO B CB  1 
ATOM   4693 C  CG  . PRO B 1 89  ? -20.991 -6.805  32.972  1   14.95  ? 81   PRO B CG  1 
ATOM   4694 C  CD  . PRO B 1 89  ? -20.137 -5.951  32.029  1   14.274 ? 81   PRO B CD  1 
ATOM   4695 N  N   . PRO B 1 90  ? -23.218 -8.325  29.222  1   12.87  ? 82   PRO B N   1 
ATOM   4696 C  CA  . PRO B 1 90  ? -24.465 -7.955  28.524  1   13.786 ? 82   PRO B CA  1 
ATOM   4697 C  C   . PRO B 1 90  ? -25.723 -8.499  29.213  1   14.651 ? 82   PRO B C   1 
ATOM   4698 O  O   . PRO B 1 90  ? -26.495 -9.238  28.59   1   16.288 ? 82   PRO B O   1 
ATOM   4699 C  CB  . PRO B 1 90  ? -24.171 -8.597  27.138  1   15.326 ? 82   PRO B CB  1 
ATOM   4700 C  CG  . PRO B 1 90  ? -23.382 -9.834  27.467  1   14.833 ? 82   PRO B CG  1 
ATOM   4701 C  CD  . PRO B 1 90  ? -22.419 -9.345  28.516  1   14.273 ? 82   PRO B CD  1 
ATOM   4702 N  N   . THR B 1 91  ? -25.951 -8.029  30.44   1   15.116 ? 83   THR B N   1 
ATOM   4703 C  CA  . THR B 1 91  ? -26.974 -8.652  31.288  1   16.646 ? 83   THR B CA  1 
ATOM   4704 C  C   . THR B 1 91  ? -28.379 -8.041  31.133  1   16.374 ? 83   THR B C   1 
ATOM   4705 O  O   . THR B 1 91  ? -29.277 -8.459  31.875  1   19.243 ? 83   THR B O   1 
ATOM   4706 C  CB  . THR B 1 91  ? -26.503 -8.52   32.75   1   18.658 ? 83   THR B CB  1 
ATOM   4707 O  OG1 . THR B 1 91  ? -26.301 -7.138  33.031  1   21.209 ? 83   THR B OG1 1 
ATOM   4708 C  CG2 . THR B 1 91  ? -25.296 -9.39   33.068  1   20.66  ? 83   THR B CG2 1 
ATOM   4709 N  N   . TYR B 1 92  ? -28.605 -7.038  30.266  1   15.949 ? 84   TYR B N   1 
ATOM   4710 C  CA  . TYR B 1 92  ? -29.872 -6.288  30.311  1   14.592 ? 84   TYR B CA  1 
ATOM   4711 C  C   . TYR B 1 92  ? -31.088 -7.218  30.108  1   16.527 ? 84   TYR B C   1 
ATOM   4712 O  O   . TYR B 1 92  ? -32.063 -7.148  30.879  1   16.916 ? 84   TYR B O   1 
ATOM   4713 C  CB  . TYR B 1 92  ? -29.898 -5.127  29.288  1   17.231 ? 84   TYR B CB  1 
ATOM   4714 C  CG  . TYR B 1 92  ? -31.293 -4.527  29.193  1   14.549 ? 84   TYR B CG  1 
ATOM   4715 C  CD1 . TYR B 1 92  ? -31.761 -3.685  30.201  1   16.191 ? 84   TYR B CD1 1 
ATOM   4716 C  CD2 . TYR B 1 92  ? -32.158 -4.894  28.141  1   14.648 ? 84   TYR B CD2 1 
ATOM   4717 C  CE1 . TYR B 1 92  ? -33.101 -3.286  30.231  1   16.915 ? 84   TYR B CE1 1 
ATOM   4718 C  CE2 . TYR B 1 92  ? -33.496 -4.492  28.143  1   15.526 ? 84   TYR B CE2 1 
ATOM   4719 C  CZ  . TYR B 1 92  ? -33.928 -3.669  29.185  1   15.782 ? 84   TYR B CZ  1 
ATOM   4720 O  OH  . TYR B 1 92  ? -35.263 -3.3    29.202  1   16.349 ? 84   TYR B OH  1 
ATOM   4721 N  N   . TYR B 1 93  ? -31.048 -8.055  29.072  1   15.682 ? 85   TYR B N   1 
ATOM   4722 C  CA  . TYR B 1 93  ? -32.207 -8.867  28.726  1   18.04  ? 85   TYR B CA  1 
ATOM   4723 C  C   . TYR B 1 93  ? -31.964 -10.309 29.114  1   16.311 ? 85   TYR B C   1 
ATOM   4724 O  O   . TYR B 1 93  ? -31.05  -10.945 28.612  1   17.476 ? 85   TYR B O   1 
ATOM   4725 C  CB  . TYR B 1 93  ? -32.46  -8.762  27.236  1   18.573 ? 85   TYR B CB  1 
ATOM   4726 C  CG  . TYR B 1 93  ? -33.779 -9.413  26.82   1   17.798 ? 85   TYR B CG  1 
ATOM   4727 C  CD1 . TYR B 1 93  ? -34.989 -8.808  27.192  1   19.06  ? 85   TYR B CD1 1 
ATOM   4728 C  CD2 . TYR B 1 93  ? -33.792 -10.591 26.066  1   16.314 ? 85   TYR B CD2 1 
ATOM   4729 C  CE1 . TYR B 1 93  ? -36.202 -9.373  26.78   1   20.048 ? 85   TYR B CE1 1 
ATOM   4730 C  CE2 . TYR B 1 93  ? -34.978 -11.157 25.635  1   20.595 ? 85   TYR B CE2 1 
ATOM   4731 C  CZ  . TYR B 1 93  ? -36.166 -10.553 26.042  1   20.769 ? 85   TYR B CZ  1 
ATOM   4732 O  OH  . TYR B 1 93  ? -37.385 -11.029 25.619  1   23.189 ? 85   TYR B OH  1 
ATOM   4733 N  N   . LYS B 1 94  ? -32.83  -10.838 30.019  1   18.208 ? 86   LYS B N   1 
ATOM   4734 C  CA  . LYS B 1 94  ? -32.76  -12.251 30.405  1   18.966 ? 86   LYS B CA  1 
ATOM   4735 C  C   . LYS B 1 94  ? -31.354 -12.634 30.903  1   17.798 ? 86   LYS B C   1 
ATOM   4736 O  O   . LYS B 1 94  ? -30.863 -13.719 30.603  1   19.723 ? 86   LYS B O   1 
ATOM   4737 C  CB  . LYS B 1 94  ? -33.332 -13.177 29.311  1   20.866 ? 86   LYS B CB  1 
ATOM   4738 C  CG  . LYS B 1 94  ? -34.839 -12.967 29.036  1   23.638 ? 86   LYS B CG  1 
ATOM   4739 C  CD  . LYS B 1 94  ? -35.362 -13.929 27.981  1   29.188 ? 86   LYS B CD  1 
ATOM   4740 C  CE  . LYS B 1 94  ? -36.847 -13.688 27.848  1   33.26  ? 86   LYS B CE  1 
ATOM   4741 N  NZ  . LYS B 1 94  ? -37.398 -14.552 26.791  1   38.169 ? 86   LYS B NZ  1 
ATOM   4742 N  N   . GLY B 1 95  ? -30.703 -11.675 31.573  1   18.437 ? 87   GLY B N   1 
ATOM   4743 C  CA  . GLY B 1 95  ? -29.391 -11.912 32.166  1   18.29  ? 87   GLY B CA  1 
ATOM   4744 C  C   . GLY B 1 95  ? -28.304 -12.151 31.101  1   19.285 ? 87   GLY B C   1 
ATOM   4745 O  O   . GLY B 1 95  ? -27.217 -12.682 31.41   1   20.733 ? 87   GLY B O   1 
ATOM   4746 N  N   . GLY B 1 96  ? -28.597 -11.774 29.852  1   18.325 ? 88   GLY B N   1 
ATOM   4747 C  CA  . GLY B 1 96  ? -27.664 -12.018 28.749  1   17.475 ? 88   GLY B CA  1 
ATOM   4748 C  C   . GLY B 1 96  ? -27.602 -13.465 28.268  1   16.094 ? 88   GLY B C   1 
ATOM   4749 O  O   . GLY B 1 96  ? -26.719 -13.827 27.482  1   19.462 ? 88   GLY B O   1 
ATOM   4750 N  N   . GLU B 1 97  ? -28.555 -14.307 28.726  1   17.258 ? 89   GLU B N   1 
ATOM   4751 C  CA  . GLU B 1 97  ? -28.517 -15.735 28.448  1   18.955 ? 89   GLU B CA  1 
ATOM   4752 C  C   . GLU B 1 97  ? -28.548 -16.062 26.946  1   17.183 ? 89   GLU B C   1 
ATOM   4753 O  O   . GLU B 1 97  ? -28.005 -17.097 26.528  1   20.436 ? 89   GLU B O   1 
ATOM   4754 C  CB  . GLU B 1 97  ? -29.713 -16.352 29.18   1   24.293 ? 89   GLU B CB  1 
ATOM   4755 C  CG  . GLU B 1 97  ? -29.978 -17.828 28.886  1   31.293 ? 89   GLU B CG  1 
ATOM   4756 C  CD  . GLU B 1 97  ? -31.324 -18.311 29.425  1   44.107 ? 89   GLU B CD  1 
ATOM   4757 O  OE1 . GLU B 1 97  ? -31.589 -19.489 29.084  1   49.612 ? 89   GLU B OE1 1 
ATOM   4758 O  OE2 . GLU B 1 97  ? -32.071 -17.574 30.153  1   43.944 ? 89   GLU B OE2 1 
ATOM   4759 N  N   . LEU B 1 98  ? -29.169 -15.165 26.156  1   17.411 ? 90   LEU B N   1 
ATOM   4760 C  CA  . LEU B 1 98  ? -29.364 -15.417 24.733  1   18.499 ? 90   LEU B CA  1 
ATOM   4761 C  C   . LEU B 1 98  ? -28.487 -14.533 23.844  1   17.088 ? 90   LEU B C   1 
ATOM   4762 O  O   . LEU B 1 98  ? -28.76  -14.405 22.642  1   17.506 ? 90   LEU B O   1 
ATOM   4763 C  CB  . LEU B 1 98  ? -30.864 -15.283 24.445  1   20.136 ? 90   LEU B CB  1 
ATOM   4764 C  CG  . LEU B 1 98  ? -31.768 -16.338 25.116  1   20.929 ? 90   LEU B CG  1 
ATOM   4765 C  CD1 . LEU B 1 98  ? -33.188 -16.056 24.637  1   23.797 ? 90   LEU B CD1 1 
ATOM   4766 C  CD2 . LEU B 1 98  ? -31.351 -17.768 24.707  1   25.016 ? 90   LEU B CD2 1 
ATOM   4767 N  N   . ASN B 1 99  ? -27.42  -13.936 24.438  1   16.479 ? 91   ASN B N   1 
ATOM   4768 C  CA  . ASN B 1 99  ? -26.457 -13.227 23.606  1   16.836 ? 91   ASN B CA  1 
ATOM   4769 C  C   . ASN B 1 99  ? -25.859 -14.188 22.579  1   17.624 ? 91   ASN B C   1 
ATOM   4770 O  O   . ASN B 1 99  ? -25.634 -15.354 22.856  1   18.921 ? 91   ASN B O   1 
ATOM   4771 C  CB  . ASN B 1 99  ? -25.452 -12.491 24.488  1   16.025 ? 91   ASN B CB  1 
ATOM   4772 C  CG  . ASN B 1 99  ? -24.25  -13.321 24.885  1   19.286 ? 91   ASN B CG  1 
ATOM   4773 O  OD1 . ASN B 1 99  ? -23.343 -13.534 24.067  1   18.424 ? 91   ASN B OD1 1 
ATOM   4774 N  ND2 . ASN B 1 99  ? -24.255 -13.844 26.112  1   19.472 ? 91   ASN B ND2 1 
ATOM   4775 N  N   . ALA B 1 100 ? -25.58  -13.646 21.372  1   15.45  ? 92   ALA B N   1 
ATOM   4776 C  CA  . ALA B 1 100 ? -25.062 -14.412 20.264  1   17.687 ? 92   ALA B CA  1 
ATOM   4777 C  C   . ALA B 1 100 ? -23.587 -14.074 20.072  1   16.75  ? 92   ALA B C   1 
ATOM   4778 O  O   . ALA B 1 100 ? -23.165 -12.961 20.423  1   17.226 ? 92   ALA B O   1 
ATOM   4779 C  CB  . ALA B 1 100 ? -25.87  -14.048 19.011  1   18.574 ? 92   ALA B CB  1 
ATOM   4780 N  N   . PRO B 1 101 ? -22.786 -14.985 19.471  1   15.109 ? 93   PRO B N   1 
ATOM   4781 C  CA  . PRO B 1 101 ? -21.366 -14.701 19.233  1   15.04  ? 93   PRO B CA  1 
ATOM   4782 C  C   . PRO B 1 101 ? -21.116 -13.501 18.326  1   16.546 ? 93   PRO B C   1 
ATOM   4783 O  O   . PRO B 1 101 ? -20.033 -12.891 18.386  1   17.935 ? 93   PRO B O   1 
ATOM   4784 C  CB  . PRO B 1 101 ? -20.781 -15.988 18.632  1   17.813 ? 93   PRO B CB  1 
ATOM   4785 C  CG  . PRO B 1 101 ? -21.995 -16.744 18.135  1   18.463 ? 93   PRO B CG  1 
ATOM   4786 C  CD  . PRO B 1 101 ? -23.103 -16.396 19.126  1   16.602 ? 93   PRO B CD  1 
ATOM   4787 N  N   . ILE B 1 102 ? -22.143 -13.147 17.526  1   15.353 ? 94   ILE B N   1 
ATOM   4788 C  CA  . ILE B 1 102 ? -22.035 -12.017 16.601  1   14.748 ? 94   ILE B CA  1 
ATOM   4789 C  C   . ILE B 1 102 ? -22.537 -10.709 17.247  1   15.052 ? 94   ILE B C   1 
ATOM   4790 O  O   . ILE B 1 102 ? -22.62  -9.688  16.561  1   16.496 ? 94   ILE B O   1 
ATOM   4791 C  CB  . ILE B 1 102 ? -22.769 -12.299 15.266  1   14.536 ? 94   ILE B CB  1 
ATOM   4792 C  CG1 . ILE B 1 102 ? -24.288 -12.545 15.518  1   14.149 ? 94   ILE B CG1 1 
ATOM   4793 C  CG2 . ILE B 1 102 ? -22.103 -13.472 14.544  1   17.492 ? 94   ILE B CG2 1 
ATOM   4794 C  CD1 . ILE B 1 102 ? -25.105 -12.753 14.241  1   17.37  ? 94   ILE B CD1 1 
ATOM   4795 N  N   . ASP B 1 103 ? -22.899 -10.71  18.544  1   14.614 ? 95   ASP B N   1 
ATOM   4796 C  CA  . ASP B 1 103 ? -23.43  -9.487  19.144  1   14.702 ? 95   ASP B CA  1 
ATOM   4797 C  C   . ASP B 1 103 ? -22.417 -8.431  19.606  1   14.258 ? 95   ASP B C   1 
ATOM   4798 O  O   . ASP B 1 103 ? -22.727 -7.227  19.556  1   15.624 ? 95   ASP B O   1 
ATOM   4799 C  CB  . ASP B 1 103 ? -24.314 -9.818  20.334  1   15.023 ? 95   ASP B CB  1 
ATOM   4800 C  CG  . ASP B 1 103 ? -25.786 -10.039 20.056  1   16.298 ? 95   ASP B CG  1 
ATOM   4801 O  OD1 . ASP B 1 103 ? -26.346 -9.211  19.333  1   15.766 ? 95   ASP B OD1 1 
ATOM   4802 O  OD2 . ASP B 1 103 ? -26.337 -11.007 20.622  1   16.943 ? 95   ASP B OD2 1 
ATOM   4803 N  N   . GLY B 1 104 ? -21.275 -8.896  20.151  1   14.1   ? 96   GLY B N   1 
ATOM   4804 C  CA  . GLY B 1 104 ? -20.53  -8.047  21.086  1   13.717 ? 96   GLY B CA  1 
ATOM   4805 C  C   . GLY B 1 104 ? -19.944 -6.788  20.421  1   13.94  ? 96   GLY B C   1 
ATOM   4806 O  O   . GLY B 1 104 ? -19.585 -6.785  19.228  1   14.569 ? 96   GLY B O   1 
ATOM   4807 N  N   . ASP B 1 105 ? -19.751 -5.746  21.254  1   12.399 ? 97   ASP B N   1 
ATOM   4808 C  CA  . ASP B 1 105 ? -19.203 -4.477  20.772  1   12.348 ? 97   ASP B CA  1 
ATOM   4809 C  C   . ASP B 1 105 ? -17.97  -4.676  19.893  1   12.971 ? 97   ASP B C   1 
ATOM   4810 O  O   . ASP B 1 105 ? -17     -5.35   20.268  1   13.502 ? 97   ASP B O   1 
ATOM   4811 C  CB  . ASP B 1 105 ? -18.811 -3.58   21.946  1   12.358 ? 97   ASP B CB  1 
ATOM   4812 C  CG  . ASP B 1 105 ? -19.997 -3.301  22.847  1   14.329 ? 97   ASP B CG  1 
ATOM   4813 O  OD1 . ASP B 1 105 ? -20.95  -2.681  22.382  1   13.536 ? 97   ASP B OD1 1 
ATOM   4814 O  OD2 . ASP B 1 105 ? -20.081 -3.87   23.965  1   14.674 ? 97   ASP B OD2 1 
ATOM   4815 N  N   . GLY B 1 106 ? -17.96  -3.998  18.731  1   13.274 ? 98   GLY B N   1 
ATOM   4816 C  CA  . GLY B 1 106 ? -16.829 -4.06   17.813  1   13.542 ? 98   GLY B CA  1 
ATOM   4817 C  C   . GLY B 1 106 ? -15.574 -3.407  18.396  1   12.608 ? 98   GLY B C   1 
ATOM   4818 O  O   . GLY B 1 106 ? -15.605 -2.267  18.847  1   13.87  ? 98   GLY B O   1 
ATOM   4819 N  N   . THR B 1 107 ? -14.463 -4.12   18.239  1   12.575 ? 99   THR B N   1 
ATOM   4820 C  CA  . THR B 1 107 ? -13.142 -3.611  18.587  1   12.585 ? 99   THR B CA  1 
ATOM   4821 C  C   . THR B 1 107 ? -12.2   -3.934  17.432  1   12.886 ? 99   THR B C   1 
ATOM   4822 O  O   . THR B 1 107 ? -12.254 -5.041  16.884  1   13.359 ? 99   THR B O   1 
ATOM   4823 C  CB  . THR B 1 107 ? -12.678 -4.22   19.925  1   13.719 ? 99   THR B CB  1 
ATOM   4824 O  OG1 . THR B 1 107 ? -11.373 -3.643  20.134  1   14.221 ? 99   THR B OG1 1 
ATOM   4825 C  CG2 . THR B 1 107 ? -12.63  -5.744  19.974  1   15.083 ? 99   THR B CG2 1 
ATOM   4826 N  N   . VAL B 1 108 ? -11.426 -2.918  17.014  1   13.585 ? 100  VAL B N   1 
ATOM   4827 C  CA  . VAL B 1 108 ? -10.499 -3.035  15.909  1   13.212 ? 100  VAL B CA  1 
ATOM   4828 C  C   . VAL B 1 108 ? -9.083  -3.223  16.437  1   12.855 ? 100  VAL B C   1 
ATOM   4829 O  O   . VAL B 1 108 ? -8.647  -2.407  17.25   1   13.831 ? 100  VAL B O   1 
ATOM   4830 C  CB  . VAL B 1 108 ? -10.603 -1.841  14.939  1   13.432 ? 100  VAL B CB  1 
ATOM   4831 C  CG1 . VAL B 1 108 ? -9.529  -1.916  13.835  1   14.579 ? 100  VAL B CG1 1 
ATOM   4832 C  CG2 . VAL B 1 108 ? -12.019 -1.773  14.319  1   14.602 ? 100  VAL B CG2 1 
ATOM   4833 N  N   . ALA B 1 109 ? -8.408  -4.278  15.949  1   13.919 ? 101  ALA B N   1 
ATOM   4834 C  CA  . ALA B 1 109 ? -6.96   -4.416  16.181  1   13.578 ? 101  ALA B CA  1 
ATOM   4835 C  C   . ALA B 1 109 ? -6.248  -4.079  14.883  1   15.94  ? 101  ALA B C   1 
ATOM   4836 O  O   . ALA B 1 109 ? -6.562  -4.662  13.848  1   17.061 ? 101  ALA B O   1 
ATOM   4837 C  CB  . ALA B 1 109 ? -6.595  -5.8    16.652  1   15.558 ? 101  ALA B CB  1 
ATOM   4838 N  N   . ALA B 1 110 ? -5.289  -3.195  14.95   1   13.898 ? 102  ALA B N   1 
ATOM   4839 C  CA  . ALA B 1 110 ? -4.48   -2.783  13.805  1   13.758 ? 102  ALA B CA  1 
ATOM   4840 C  C   . ALA B 1 110 ? -3.049  -3.242  14.027  1   14.516 ? 102  ALA B C   1 
ATOM   4841 O  O   . ALA B 1 110 ? -2.457  -3.009  15.093  1   15.09  ? 102  ALA B O   1 
ATOM   4842 C  CB  . ALA B 1 110 ? -4.539  -1.289  13.673  1   13.487 ? 102  ALA B CB  1 
ATOM   4843 N  N   . PHE B 1 111 ? -2.501  -3.911  12.999  1   13.122 ? 103  PHE B N   1 
ATOM   4844 C  CA  . PHE B 1 111 ? -1.094  -4.323  13.003  1   14.886 ? 103  PHE B CA  1 
ATOM   4845 C  C   . PHE B 1 111 ? -0.435  -3.632  11.809  1   15.721 ? 103  PHE B C   1 
ATOM   4846 O  O   . PHE B 1 111 ? -0.737  -3.984  10.67   1   14.878 ? 103  PHE B O   1 
ATOM   4847 C  CB  . PHE B 1 111 ? -0.959  -5.822  12.854  1   14.845 ? 103  PHE B CB  1 
ATOM   4848 C  CG  . PHE B 1 111 ? -1.61   -6.611  13.978  1   14.579 ? 103  PHE B CG  1 
ATOM   4849 C  CD1 . PHE B 1 111 ? -2.951  -6.964  13.877  1   15.411 ? 103  PHE B CD1 1 
ATOM   4850 C  CD2 . PHE B 1 111 ? -0.88   -6.966  15.125  1   15.27  ? 103  PHE B CD2 1 
ATOM   4851 C  CE1 . PHE B 1 111 ? -3.566  -7.687  14.91   1   14.888 ? 103  PHE B CE1 1 
ATOM   4852 C  CE2 . PHE B 1 111 ? -1.506  -7.712  16.14   1   16.964 ? 103  PHE B CE2 1 
ATOM   4853 C  CZ  . PHE B 1 111 ? -2.848  -8.053  16.033  1   17.012 ? 103  PHE B CZ  1 
ATOM   4854 N  N   . ARG B 1 112 ? 0.383   -2.616  12.088  1   16.104 ? 104  ARG B N   1 
ATOM   4855 C  CA  . ARG B 1 112 ? 0.955   -1.806  11.02   1   16.363 ? 104  ARG B CA  1 
ATOM   4856 C  C   . ARG B 1 112 ? 2.391   -2.218  10.744  1   16.2   ? 104  ARG B C   1 
ATOM   4857 O  O   . ARG B 1 112 ? 3.217   -2.226  11.653  1   16.563 ? 104  ARG B O   1 
ATOM   4858 C  CB  . ARG B 1 112 ? 0.881   -0.305  11.319  1   14.939 ? 104  ARG B CB  1 
ATOM   4859 C  CG  . ARG B 1 112 ? 1.418   0.521   10.153  1   15.33  ? 104  ARG B CG  1 
ATOM   4860 C  CD  . ARG B 1 112 ? 0.97    1.952   10.26   1   15.679 ? 104  ARG B CD  1 
ATOM   4861 N  NE  . ARG B 1 112 ? -0.478  2.046   9.972   1   14.908 ? 104  ARG B NE  1 
ATOM   4862 C  CZ  . ARG B 1 112 ? -1.175  3.157   10.089  1   16.559 ? 104  ARG B CZ  1 
ATOM   4863 N  NH1 . ARG B 1 112 ? -0.638  4.287   10.515  1   16.608 ? 104  ARG B NH1 1 
ATOM   4864 N  NH2 . ARG B 1 112 ? -2.48   3.139   9.771   1   16.223 ? 104  ARG B NH2 1 
ATOM   4865 N  N   . PHE B 1 113 ? 2.651   -2.586  9.489   1   14.882 ? 105  PHE B N   1 
ATOM   4866 C  CA  . PHE B 1 113 ? 3.958   -3.077  9.028   1   14.844 ? 105  PHE B CA  1 
ATOM   4867 C  C   . PHE B 1 113 ? 4.608   -1.99   8.164   1   16.549 ? 105  PHE B C   1 
ATOM   4868 O  O   . PHE B 1 113 ? 4.048   -1.548  7.159   1   16.43  ? 105  PHE B O   1 
ATOM   4869 C  CB  . PHE B 1 113 ? 3.717   -4.264  8.095   1   16.195 ? 105  PHE B CB  1 
ATOM   4870 C  CG  . PHE B 1 113 ? 3.157   -5.491  8.817   1   17.197 ? 105  PHE B CG  1 
ATOM   4871 C  CD1 . PHE B 1 113 ? 1.802   -5.552  9.164   1   16.297 ? 105  PHE B CD1 1 
ATOM   4872 C  CD2 . PHE B 1 113 ? 3.967   -6.597  9.084   1   18.239 ? 105  PHE B CD2 1 
ATOM   4873 C  CE1 . PHE B 1 113 ? 1.293   -6.66   9.833   1   16.365 ? 105  PHE B CE1 1 
ATOM   4874 C  CE2 . PHE B 1 113 ? 3.455   -7.716  9.771   1   20.62  ? 105  PHE B CE2 1 
ATOM   4875 C  CZ  . PHE B 1 113 ? 2.101   -7.744  10.106  1   17.776 ? 105  PHE B CZ  1 
ATOM   4876 N  N   . LYS B 1 114 ? 5.801   -1.532  8.6     1   17.214 ? 106  LYS B N   1 
ATOM   4877 C  CA  . LYS B 1 114 ? 6.52    -0.543  7.803   1   19.683 ? 106  LYS B CA  1 
ATOM   4878 C  C   . LYS B 1 114 ? 8.005   -0.768  8.045   1   20.301 ? 106  LYS B C   1 
ATOM   4879 O  O   . LYS B 1 114 ? 8.44    -0.756  9.194   1   18.958 ? 106  LYS B O   1 
ATOM   4880 C  CB  . LYS B 1 114 ? 6.098   0.876   8.218   1   20.262 ? 106  LYS B CB  1 
ATOM   4881 C  CG  . LYS B 1 114 ? 6.733   1.996   7.397   1   24.442 ? 106  LYS B CG  1 
ATOM   4882 C  CD  . LYS B 1 114 ? 5.914   3.237   7.762   1   25.02  ? 106  LYS B CD  1 
ATOM   4883 C  CE  . LYS B 1 114 ? 6.169   4.32    6.791   1   33.349 ? 106  LYS B CE  1 
ATOM   4884 N  NZ  . LYS B 1 114 ? 5.925   5.56    7.522   1   35.862 ? 106  LYS B NZ  1 
ATOM   4885 N  N   . ASP B 1 115 ? 8.742   -1.065  6.967   1   21.891 ? 107  ASP B N   1 
ATOM   4886 C  CA  . ASP B 1 115 ? 10.203  -1.218  7.061   1   21.966 ? 107  ASP B CA  1 
ATOM   4887 C  C   . ASP B 1 115 ? 10.578  -2.277  8.092   1   18.68  ? 107  ASP B C   1 
ATOM   4888 O  O   . ASP B 1 115 ? 11.525  -2.066  8.85    1   22.207 ? 107  ASP B O   1 
ATOM   4889 C  CB  . ASP B 1 115 ? 10.869  0.154   7.234   1   26.406 ? 107  ASP B CB  1 
ATOM   4890 C  CG  . ASP B 1 115 ? 10.622  1.096   6.054   1   31.292 ? 107  ASP B CG  1 
ATOM   4891 O  OD1 . ASP B 1 115 ? 10.568  0.623   4.9     1   37.426 ? 107  ASP B OD1 1 
ATOM   4892 O  OD2 . ASP B 1 115 ? 10.441  2.28    6.29    1   35.361 ? 107  ASP B OD2 1 
ATOM   4893 N  N   . GLY B 1 116 ? 9.829   -3.399  8.143   1   19.259 ? 108  GLY B N   1 
ATOM   4894 C  CA  . GLY B 1 116 ? 10.147  -4.544  9       1   19.655 ? 108  GLY B CA  1 
ATOM   4895 C  C   . GLY B 1 116 ? 9.651   -4.423  10.452  1   18.283 ? 108  GLY B C   1 
ATOM   4896 O  O   . GLY B 1 116 ? 9.767   -5.43   11.192  1   23.217 ? 108  GLY B O   1 
ATOM   4897 N  N   . LYS B 1 117 ? 9.165   -3.228  10.84   1   19.788 ? 109  LYS B N   1 
ATOM   4898 C  CA  . LYS B 1 117 ? 8.683   -2.934  12.191  1   20.297 ? 109  LYS B CA  1 
ATOM   4899 C  C   . LYS B 1 117 ? 7.166   -3.12   12.208  1   18.311 ? 109  LYS B C   1 
ATOM   4900 O  O   . LYS B 1 117 ? 6.496   -2.708  11.249  1   19.269 ? 109  LYS B O   1 
ATOM   4901 C  CB  . LYS B 1 117 ? 9.001   -1.517  12.731  1   21.844 ? 109  LYS B CB  1 
ATOM   4902 C  CG  . LYS B 1 117 ? 8.394   -1.189  14.141  1   22.955 ? 109  LYS B CG  1 
ATOM   4903 C  CD  . LYS B 1 117 ? 8.871   0.076   14.89   1   23.963 ? 109  LYS B CD  1 
ATOM   4904 C  CE  . LYS B 1 117 ? 8.441   1.418   14.343  1   25.912 ? 109  LYS B CE  1 
ATOM   4905 N  NZ  . LYS B 1 117 ? 6.987   1.487   14.22   1   26.268 ? 109  LYS B NZ  1 
ATOM   4906 N  N   . VAL B 1 118 ? 6.667   -3.743  13.291  1   14.219 ? 110  VAL B N   1 
ATOM   4907 C  CA  . VAL B 1 118 ? 5.222   -3.876  13.461  1   16.421 ? 110  VAL B CA  1 
ATOM   4908 C  C   . VAL B 1 118 ? 4.814   -3.13   14.73   1   14.852 ? 110  VAL B C   1 
ATOM   4909 O  O   . VAL B 1 118 ? 5.404   -3.424  15.799  1   16.312 ? 110  VAL B O   1 
ATOM   4910 C  CB  . VAL B 1 118 ? 4.809   -5.347  13.541  1   17.583 ? 110  VAL B CB  1 
ATOM   4911 C  CG1 . VAL B 1 118 ? 3.285   -5.445  13.455  1   17.332 ? 110  VAL B CG1 1 
ATOM   4912 C  CG2 . VAL B 1 118 ? 5.398   -6.152  12.385  1   20.413 ? 110  VAL B CG2 1 
ATOM   4913 N  N   . ASP B 1 119 ? 3.733   -2.329  14.624  1   14.059 ? 111  ASP B N   1 
ATOM   4914 C  CA  . ASP B 1 119 ? 3.097   -1.723  15.798  1   13.702 ? 111  ASP B CA  1 
ATOM   4915 C  C   . ASP B 1 119 ? 1.676   -2.264  15.877  1   15.693 ? 111  ASP B C   1 
ATOM   4916 O  O   . ASP B 1 119 ? 1.101   -2.687  14.86   1   14.791 ? 111  ASP B O   1 
ATOM   4917 C  CB  . ASP B 1 119 ? 3.043   -0.203  15.751  1   15.4   ? 111  ASP B CB  1 
ATOM   4918 C  CG  . ASP B 1 119 ? 4.39    0.508   15.711  1   16.636 ? 111  ASP B CG  1 
ATOM   4919 O  OD1 . ASP B 1 119 ? 5.377   -0.056  16.233  1   15.48  ? 111  ASP B OD1 1 
ATOM   4920 O  OD2 . ASP B 1 119 ? 4.387   1.661   15.265  1   17.667 ? 111  ASP B OD2 1 
ATOM   4921 N  N   . TYR B 1 120 ? 1.137   -2.212  17.094  1   14.978 ? 112  TYR B N   1 
ATOM   4922 C  CA  . TYR B 1 120 ? -0.228  -2.669  17.302  1   14.252 ? 112  TYR B CA  1 
ATOM   4923 C  C   . TYR B 1 120 ? -1.013  -1.584  18.023  1   14.918 ? 112  TYR B C   1 
ATOM   4924 O  O   . TYR B 1 120 ? -0.512  -0.96   18.966  1   14.13  ? 112  TYR B O   1 
ATOM   4925 C  CB  . TYR B 1 120 ? -0.216  -3.945  18.142  1   13.734 ? 112  TYR B CB  1 
ATOM   4926 C  CG  . TYR B 1 120 ? -1.451  -4.301  18.956  1   16.037 ? 112  TYR B CG  1 
ATOM   4927 C  CD1 . TYR B 1 120 ? -2.533  -5.019  18.424  1   15.545 ? 112  TYR B CD1 1 
ATOM   4928 C  CD2 . TYR B 1 120 ? -1.477  -3.904  20.292  1   16.996 ? 112  TYR B CD2 1 
ATOM   4929 C  CE1 . TYR B 1 120 ? -3.591  -5.376  19.291  1   16.39  ? 112  TYR B CE1 1 
ATOM   4930 C  CE2 . TYR B 1 120 ? -2.55   -4.186  21.123  1   19.871 ? 112  TYR B CE2 1 
ATOM   4931 C  CZ  . TYR B 1 120 ? -3.59   -4.932  20.616  1   16.788 ? 112  TYR B CZ  1 
ATOM   4932 O  OH  . TYR B 1 120 ? -4.556  -5.087  21.629  1   19.867 ? 112  TYR B OH  1 
ATOM   4933 N  N   . ARG B 1 121 ? -2.294  -1.453  17.618  1   14.142 ? 113  ARG B N   1 
ATOM   4934 C  CA  . ARG B 1 121 ? -3.232  -0.616  18.37   1   13.885 ? 113  ARG B CA  1 
ATOM   4935 C  C   . ARG B 1 121 ? -4.581  -1.324  18.352  1   16.933 ? 113  ARG B C   1 
ATOM   4936 O  O   . ARG B 1 121 ? -4.998  -1.871  17.309  1   16.756 ? 113  ARG B O   1 
ATOM   4937 C  CB  . ARG B 1 121 ? -3.412  0.779   17.747  1   14.983 ? 113  ARG B CB  1 
ATOM   4938 C  CG  . ARG B 1 121 ? -4.486  1.596   18.489  1   14.721 ? 113  ARG B CG  1 
ATOM   4939 C  CD  . ARG B 1 121 ? -4.629  3.02    17.906  1   15.997 ? 113  ARG B CD  1 
ATOM   4940 N  NE  . ARG B 1 121 ? -3.536  3.93    18.277  1   14.901 ? 113  ARG B NE  1 
ATOM   4941 C  CZ  . ARG B 1 121 ? -3.464  4.611   19.424  1   16.265 ? 113  ARG B CZ  1 
ATOM   4942 N  NH1 . ARG B 1 121 ? -4.313  4.407   20.446  1   17.435 ? 113  ARG B NH1 1 
ATOM   4943 N  NH2 . ARG B 1 121 ? -2.44   5.413   19.6    1   16.989 ? 113  ARG B NH2 1 
ATOM   4944 N  N   . GLN B 1 122 ? -5.277  -1.307  19.49   1   14.223 ? 114  GLN B N   1 
ATOM   4945 C  CA  . GLN B 1 122 ? -6.63   -1.842  19.534  1   14.677 ? 114  GLN B CA  1 
ATOM   4946 C  C   . GLN B 1 122 ? -7.556  -0.855  20.211  1   15.143 ? 114  GLN B C   1 
ATOM   4947 O  O   . GLN B 1 122 ? -7.138  -0.18   21.153  1   13.652 ? 114  GLN B O   1 
ATOM   4948 C  CB  . GLN B 1 122 ? -6.644  -3.14   20.32   1   14.001 ? 114  GLN B CB  1 
ATOM   4949 C  CG  . GLN B 1 122 ? -8.042  -3.741  20.354  1   16.887 ? 114  GLN B CG  1 
ATOM   4950 C  CD  . GLN B 1 122 ? -8.036  -5.209  20.67   1   16.936 ? 114  GLN B CD  1 
ATOM   4951 O  OE1 . GLN B 1 122 ? -7.044  -5.798  21.093  1   21.553 ? 114  GLN B OE1 1 
ATOM   4952 N  NE2 . GLN B 1 122 ? -9.197  -5.828  20.522  1   19.368 ? 114  GLN B NE2 1 
ATOM   4953 N  N   . ARG B 1 123 ? -8.799  -0.744  19.698  1   14.199 ? 115  ARG B N   1 
ATOM   4954 C  CA  . ARG B 1 123 ? -9.723  0.242   20.273  1   13.438 ? 115  ARG B CA  1 
ATOM   4955 C  C   . ARG B 1 123 ? -11.148 -0.155  19.907  1   12.93  ? 115  ARG B C   1 
ATOM   4956 O  O   . ARG B 1 123 ? -11.429 -0.579  18.78   1   13.043 ? 115  ARG B O   1 
ATOM   4957 C  CB  . ARG B 1 123 ? -9.441  1.646   19.721  1   14.372 ? 115  ARG B CB  1 
ATOM   4958 C  CG  . ARG B 1 123 ? -10.006 2.767   20.591  1   14.496 ? 115  ARG B CG  1 
ATOM   4959 C  CD  . ARG B 1 123 ? -9.482  4.096   20.037  1   15.536 ? 115  ARG B CD  1 
ATOM   4960 N  NE  . ARG B 1 123 ? -9.976  5.153   20.932  1   19.257 ? 115  ARG B NE  1 
ATOM   4961 C  CZ  . ARG B 1 123 ? -9.474  6.381   20.865  1   20.884 ? 115  ARG B CZ  1 
ATOM   4962 N  NH1 . ARG B 1 123 ? -8.529  6.715   19.974  1   19.68  ? 115  ARG B NH1 1 
ATOM   4963 N  NH2 . ARG B 1 123 ? -9.979  7.265   21.705  1   21.762 ? 115  ARG B NH2 1 
ATOM   4964 N  N   . PHE B 1 124 ? -12.074 0.067   20.853  1   11.518 ? 116  PHE B N   1 
ATOM   4965 C  CA  . PHE B 1 124 ? -13.49  -0.122  20.547  1   11.935 ? 116  PHE B CA  1 
ATOM   4966 C  C   . PHE B 1 124 ? -13.952 0.992   19.619  1   12.86  ? 116  PHE B C   1 
ATOM   4967 O  O   . PHE B 1 124 ? -13.626 2.187   19.78   1   13.941 ? 116  PHE B O   1 
ATOM   4968 C  CB  . PHE B 1 124 ? -14.333 0.008   21.815  1   12.369 ? 116  PHE B CB  1 
ATOM   4969 C  CG  . PHE B 1 124 ? -14.305 -1.252  22.661  1   12.806 ? 116  PHE B CG  1 
ATOM   4970 C  CD1 . PHE B 1 124 ? -14.969 -2.391  22.168  1   10.966 ? 116  PHE B CD1 1 
ATOM   4971 C  CD2 . PHE B 1 124 ? -13.648 -1.304  23.887  1   13.128 ? 116  PHE B CD2 1 
ATOM   4972 C  CE1 . PHE B 1 124 ? -14.956 -3.571  22.902  1   11.839 ? 116  PHE B CE1 1 
ATOM   4973 C  CE2 . PHE B 1 124 ? -13.613 -2.51   24.634  1   12.826 ? 116  PHE B CE2 1 
ATOM   4974 C  CZ  . PHE B 1 124 ? -14.271 -3.614  24.134  1   13.752 ? 116  PHE B CZ  1 
ATOM   4975 N  N   . VAL B 1 125 ? -14.849 0.582   18.706  1   13.37  ? 117  VAL B N   1 
ATOM   4976 C  CA  . VAL B 1 125 ? -15.648 1.545   17.919  1   12.659 ? 117  VAL B CA  1 
ATOM   4977 C  C   . VAL B 1 125 ? -16.613 2.273   18.864  1   12.644 ? 117  VAL B C   1 
ATOM   4978 O  O   . VAL B 1 125 ? -17.265 1.609   19.686  1   14.031 ? 117  VAL B O   1 
ATOM   4979 C  CB  . VAL B 1 125 ? -16.458 0.828   16.826  1   13.097 ? 117  VAL B CB  1 
ATOM   4980 C  CG1 . VAL B 1 125 ? -17.143 1.866   15.921  1   15.994 ? 117  VAL B CG1 1 
ATOM   4981 C  CG2 . VAL B 1 125 ? -15.615 -0.14   16      1   13.998 ? 117  VAL B CG2 1 
ATOM   4982 N  N   . GLU B 1 126 ? -16.672 3.623   18.818  1   13.84  ? 118  GLU B N   1 
ATOM   4983 C  CA  . GLU B 1 126 ? -17.537 4.312   19.753  1   14.347 ? 118  GLU B CA  1 
ATOM   4984 C  C   . GLU B 1 126 ? -18.936 4.403   19.142  1   14.755 ? 118  GLU B C   1 
ATOM   4985 O  O   . GLU B 1 126 ? -19.426 5.501   18.805  1   16.992 ? 118  GLU B O   1 
ATOM   4986 C  CB  . GLU B 1 126 ? -17.074 5.735   20.041  1   16.455 ? 118  GLU B CB  1 
ATOM   4987 C  CG  . GLU B 1 126 ? -15.767 5.799   20.795  1   18.057 ? 118  GLU B CG  1 
ATOM   4988 C  CD  . GLU B 1 126 ? -15.588 7.289   21.115  1   22.629 ? 118  GLU B CD  1 
ATOM   4989 O  OE1 . GLU B 1 126 ? -16.272 8.277   20.609  1   23.633 ? 118  GLU B OE1 1 
ATOM   4990 O  OE2 . GLU B 1 126 ? -14.817 7.513   22.038  1   20.923 ? 118  GLU B OE2 1 
ATOM   4991 N  N   . THR B 1 127 ? -19.551 3.243   18.904  1   12.352 ? 119  THR B N   1 
ATOM   4992 C  CA  . THR B 1 127 ? -20.937 3.211   18.416  1   12.369 ? 119  THR B CA  1 
ATOM   4993 C  C   . THR B 1 127 ? -21.843 3.917   19.437  1   12.849 ? 119  THR B C   1 
ATOM   4994 O  O   . THR B 1 127 ? -21.507 4.015   20.625  1   13.819 ? 119  THR B O   1 
ATOM   4995 C  CB  . THR B 1 127 ? -21.427 1.795   18.189  1   12.88  ? 119  THR B CB  1 
ATOM   4996 O  OG1 . THR B 1 127 ? -21.561 1.165   19.487  1   13.017 ? 119  THR B OG1 1 
ATOM   4997 C  CG2 . THR B 1 127 ? -20.508 0.999   17.295  1   13.091 ? 119  THR B CG2 1 
ATOM   4998 N  N   . ASP B 1 128 ? -23.026 4.362   18.984  1   13.222 ? 120  ASP B N   1 
ATOM   4999 C  CA  . ASP B 1 128 ? -23.941 4.99    19.94   1   13.471 ? 120  ASP B CA  1 
ATOM   5000 C  C   . ASP B 1 128 ? -24.284 4.032   21.086  1   12.312 ? 120  ASP B C   1 
ATOM   5001 O  O   . ASP B 1 128 ? -24.4   4.442   22.247  1   13.372 ? 120  ASP B O   1 
ATOM   5002 C  CB  . ASP B 1 128 ? -25.192 5.502   19.246  1   13.578 ? 120  ASP B CB  1 
ATOM   5003 C  CG  . ASP B 1 128 ? -24.915 6.729   18.395  1   16.814 ? 120  ASP B CG  1 
ATOM   5004 O  OD1 . ASP B 1 128 ? -23.828 7.35    18.61   1   16.729 ? 120  ASP B OD1 1 
ATOM   5005 O  OD2 . ASP B 1 128 ? -25.77  7.017   17.522  1   16.148 ? 120  ASP B OD2 1 
ATOM   5006 N  N   . ARG B 1 129 ? -24.392 2.747   20.765  1   12.773 ? 121  ARG B N   1 
ATOM   5007 C  CA  . ARG B 1 129 ? -24.62  1.681   21.73   1   12.929 ? 121  ARG B CA  1 
ATOM   5008 C  C   . ARG B 1 129 ? -23.477 1.572   22.752  1   14.18  ? 121  ARG B C   1 
ATOM   5009 O  O   . ARG B 1 129 ? -23.735 1.482   23.95   1   13.356 ? 121  ARG B O   1 
ATOM   5010 C  CB  . ARG B 1 129 ? -24.816 0.392   20.926  1   13.193 ? 121  ARG B CB  1 
ATOM   5011 C  CG  . ARG B 1 129 ? -24.774 -0.893  21.758  1   13.074 ? 121  ARG B CG  1 
ATOM   5012 C  CD  . ARG B 1 129 ? -25.515 -1.965  20.957  1   13.14  ? 121  ARG B CD  1 
ATOM   5013 N  NE  . ARG B 1 129 ? -25.41  -3.26   21.641  1   14.503 ? 121  ARG B NE  1 
ATOM   5014 C  CZ  . ARG B 1 129 ? -26.03  -4.339  21.205  1   15.203 ? 121  ARG B CZ  1 
ATOM   5015 N  NH1 . ARG B 1 129 ? -26.881 -4.206  20.172  1   14.758 ? 121  ARG B NH1 1 
ATOM   5016 N  NH2 . ARG B 1 129 ? -25.818 -5.515  21.772  1   14.435 ? 121  ARG B NH2 1 
ATOM   5017 N  N   . PHE B 1 130 ? -22.237 1.515   22.235  1   13.357 ? 122  PHE B N   1 
ATOM   5018 C  CA  . PHE B 1 130 ? -21.094 1.434   23.135  1   13.76  ? 122  PHE B CA  1 
ATOM   5019 C  C   . PHE B 1 130 ? -21.045 2.643   24.041  1   13.233 ? 122  PHE B C   1 
ATOM   5020 O  O   . PHE B 1 130 ? -20.72  2.491   25.222  1   13.732 ? 122  PHE B O   1 
ATOM   5021 C  CB  . PHE B 1 130 ? -19.838 1.363   22.253  1   12.816 ? 122  PHE B CB  1 
ATOM   5022 C  CG  . PHE B 1 130 ? -18.516 1.548   22.992  1   12.49  ? 122  PHE B CG  1 
ATOM   5023 C  CD1 . PHE B 1 130 ? -17.872 0.469   23.607  1   12.864 ? 122  PHE B CD1 1 
ATOM   5024 C  CD2 . PHE B 1 130 ? -17.984 2.834   23.148  1   14.593 ? 122  PHE B CD2 1 
ATOM   5025 C  CE1 . PHE B 1 130 ? -16.675 0.665   24.317  1   13.349 ? 122  PHE B CE1 1 
ATOM   5026 C  CE2 . PHE B 1 130 ? -16.755 3.029   23.803  1   14.247 ? 122  PHE B CE2 1 
ATOM   5027 C  CZ  . PHE B 1 130 ? -16.126 1.94    24.41   1   13.756 ? 122  PHE B CZ  1 
ATOM   5028 N  N   . LYS B 1 131 ? -21.324 3.844   23.489  1   13.143 ? 123  LYS B N   1 
ATOM   5029 C  CA  . LYS B 1 131 ? -21.22  5.049   24.318  1   13.578 ? 123  LYS B CA  1 
ATOM   5030 C  C   . LYS B 1 131 ? -22.252 5       25.449  1   13.951 ? 123  LYS B C   1 
ATOM   5031 O  O   . LYS B 1 131 ? -21.917 5.35    26.584  1   14.138 ? 123  LYS B O   1 
ATOM   5032 C  CB  . LYS B 1 131 ? -21.311 6.358   23.529  1   13.698 ? 123  LYS B CB  1 
ATOM   5033 C  CG  . LYS B 1 131 ? -20.262 6.453   22.402  1   14.101 ? 123  LYS B CG  1 
ATOM   5034 C  CD  . LYS B 1 131 ? -20.119 7.865   21.809  1   14.54  ? 123  LYS B CD  1 
ATOM   5035 C  CE  . LYS B 1 131 ? -21.362 8.384   21.077  1   13.776 ? 123  LYS B CE  1 
ATOM   5036 N  NZ  . LYS B 1 131 ? -22.379 8.949   22.008  1   15.43  ? 123  LYS B NZ  1 
ATOM   5037 N  N   . VAL B 1 132 ? -23.501 4.616   25.098  1   13.892 ? 124  VAL B N   1 
ATOM   5038 C  CA  . VAL B 1 132 ? -24.548 4.525   26.128  1   14.478 ? 124  VAL B CA  1 
ATOM   5039 C  C   . VAL B 1 132 ? -24.109 3.564   27.235  1   14.202 ? 124  VAL B C   1 
ATOM   5040 O  O   . VAL B 1 132 ? -24.238 3.89    28.434  1   15.932 ? 124  VAL B O   1 
ATOM   5041 C  CB  . VAL B 1 132 ? -25.852 4.028   25.454  1   16.805 ? 124  VAL B CB  1 
ATOM   5042 C  CG1 . VAL B 1 132 ? -26.821 3.442   26.477  1   25.364 ? 124  VAL B CG1 1 
ATOM   5043 C  CG2 . VAL B 1 132 ? -26.492 5.187   24.699  1   21.041 ? 124  VAL B CG2 1 
ATOM   5044 N  N   . GLU B 1 133 ? -23.635 2.375   26.837  1   13.802 ? 125  GLU B N   1 
ATOM   5045 C  CA  . GLU B 1 133 ? -23.361 1.381   27.867  1   13.471 ? 125  GLU B CA  1 
ATOM   5046 C  C   . GLU B 1 133 ? -22.124 1.75    28.692  1   13.976 ? 125  GLU B C   1 
ATOM   5047 O  O   . GLU B 1 133 ? -22.073 1.424   29.887  1   14.704 ? 125  GLU B O   1 
ATOM   5048 C  CB  . GLU B 1 133 ? -23.239 -0.002  27.229  1   13.495 ? 125  GLU B CB  1 
ATOM   5049 C  CG  . GLU B 1 133 ? -24.576 -0.488  26.636  1   13.839 ? 125  GLU B CG  1 
ATOM   5050 C  CD  . GLU B 1 133 ? -24.572 -1.949  26.267  1   14.524 ? 125  GLU B CD  1 
ATOM   5051 O  OE1 . GLU B 1 133 ? -23.485 -2.598  26.089  1   15.091 ? 125  GLU B OE1 1 
ATOM   5052 O  OE2 . GLU B 1 133 ? -25.686 -2.546  26.202  1   13.872 ? 125  GLU B OE2 1 
ATOM   5053 N  N   . ARG B 1 134 ? -21.104 2.354   28.07   1   12.588 ? 126  ARG B N   1 
ATOM   5054 C  CA  . ARG B 1 134 ? -19.911 2.72    28.831  1   13.099 ? 126  ARG B CA  1 
ATOM   5055 C  C   . ARG B 1 134 ? -20.255 3.832   29.832  1   14.484 ? 126  ARG B C   1 
ATOM   5056 O  O   . ARG B 1 134 ? -19.823 3.779   30.981  1   14.557 ? 126  ARG B O   1 
ATOM   5057 C  CB  . ARG B 1 134 ? -18.791 3.156   27.875  1   13.385 ? 126  ARG B CB  1 
ATOM   5058 C  CG  . ARG B 1 134 ? -17.586 3.611   28.704  1   13.246 ? 126  ARG B CG  1 
ATOM   5059 C  CD  . ARG B 1 134 ? -16.23  3.565   27.964  1   13.406 ? 126  ARG B CD  1 
ATOM   5060 N  NE  . ARG B 1 134 ? -15.82  2.157   27.845  1   12.702 ? 126  ARG B NE  1 
ATOM   5061 C  CZ  . ARG B 1 134 ? -14.638 1.792   27.347  1   13.013 ? 126  ARG B CZ  1 
ATOM   5062 N  NH1 . ARG B 1 134 ? -13.756 2.696   26.945  1   12.64  ? 126  ARG B NH1 1 
ATOM   5063 N  NH2 . ARG B 1 134 ? -14.358 0.488   27.203  1   14.109 ? 126  ARG B NH2 1 
ATOM   5064 N  N   . ARG B 1 135 ? -21.006 4.852   29.379  1   14.77  ? 127  ARG B N   1 
ATOM   5065 C  CA  . ARG B 1 135 ? -21.33  5.988   30.263  1   14.876 ? 127  ARG B CA  1 
ATOM   5066 C  C   . ARG B 1 135 ? -22.217 5.498   31.415  1   15.827 ? 127  ARG B C   1 
ATOM   5067 O  O   . ARG B 1 135 ? -22.07  6.018   32.52   1   17.746 ? 127  ARG B O   1 
ATOM   5068 C  CB  . ARG B 1 135 ? -22.043 7.073   29.447  1   14.48  ? 127  ARG B CB  1 
ATOM   5069 C  CG  . ARG B 1 135 ? -21.051 7.777   28.517  1   15.067 ? 127  ARG B CG  1 
ATOM   5070 C  CD  . ARG B 1 135 ? -21.72  8.766   27.542  1   16.748 ? 127  ARG B CD  1 
ATOM   5071 N  NE  . ARG B 1 135 ? -22.323 9.832   28.352  1   18.333 ? 127  ARG B NE  1 
ATOM   5072 C  CZ  . ARG B 1 135 ? -21.675 10.852  28.917  1   18.812 ? 127  ARG B CZ  1 
ATOM   5073 N  NH1 . ARG B 1 135 ? -20.397 11.088  28.63   1   20.524 ? 127  ARG B NH1 1 
ATOM   5074 N  NH2 . ARG B 1 135 ? -22.348 11.641  29.761  1   24.485 ? 127  ARG B NH2 1 
ATOM   5075 N  N   . ALA B 1 136 ? -23.081 4.512   31.191  1   15.227 ? 128  ALA B N   1 
ATOM   5076 C  CA  . ALA B 1 136 ? -23.942 3.979   32.245  1   15.262 ? 128  ALA B CA  1 
ATOM   5077 C  C   . ALA B 1 136 ? -23.218 2.89    33.035  1   15.736 ? 128  ALA B C   1 
ATOM   5078 O  O   . ALA B 1 136 ? -23.718 2.428   34.073  1   17.576 ? 128  ALA B O   1 
ATOM   5079 C  CB  . ALA B 1 136 ? -25.217 3.453   31.629  1   18.23  ? 128  ALA B CB  1 
ATOM   5080 N  N   . ARG B 1 137 ? -22.044 2.42    32.55   1   15.482 ? 129  ARG B N   1 
ATOM   5081 C  CA  . ARG B 1 137 ? -21.385 1.218   33.064  1   15.645 ? 129  ARG B CA  1 
ATOM   5082 C  C   . ARG B 1 137 ? -22.369 0.053   33.199  1   17.649 ? 129  ARG B C   1 
ATOM   5083 O  O   . ARG B 1 137 ? -22.395 -0.658  34.212  1   17.935 ? 129  ARG B O   1 
ATOM   5084 C  CB  . ARG B 1 137 ? -20.58  1.489   34.343  1   17.49  ? 129  ARG B CB  1 
ATOM   5085 C  CG  . ARG B 1 137 ? -19.515 0.43    34.665  1   18.435 ? 129  ARG B CG  1 
ATOM   5086 C  CD  . ARG B 1 137 ? -18.788 0.741   35.97   1   18.831 ? 129  ARG B CD  1 
ATOM   5087 N  NE  . ARG B 1 137 ? -17.948 1.958   36.01   1   20.009 ? 129  ARG B NE  1 
ATOM   5088 C  CZ  . ARG B 1 137 ? -16.604 1.955   35.904  1   18.132 ? 129  ARG B CZ  1 
ATOM   5089 N  NH1 . ARG B 1 137 ? -15.975 0.803   35.789  1   16.696 ? 129  ARG B NH1 1 
ATOM   5090 N  NH2 . ARG B 1 137 ? -15.92  3.082   35.913  1   20.419 ? 129  ARG B NH2 1 
ATOM   5091 N  N   . LYS B 1 138 ? -23.197 -0.132  32.159  1   16.407 ? 130  LYS B N   1 
ATOM   5092 C  CA  . LYS B 1 138 ? -24.309 -1.068  32.261  1   16.965 ? 130  LYS B CA  1 
ATOM   5093 C  C   . LYS B 1 138 ? -24.839 -1.442  30.884  1   15.006 ? 130  LYS B C   1 
ATOM   5094 O  O   . LYS B 1 138 ? -24.979 -0.578  30.007  1   16.231 ? 130  LYS B O   1 
ATOM   5095 C  CB  . LYS B 1 138 ? -25.463 -0.421  33.038  1   20.565 ? 130  LYS B CB  1 
ATOM   5096 C  CG  . LYS B 1 138 ? -26.365 -1.502  33.602  1   28.292 ? 130  LYS B CG  1 
ATOM   5097 C  CD  . LYS B 1 138 ? -27.312 -1.121  34.74   1   36.071 ? 130  LYS B CD  1 
ATOM   5098 C  CE  . LYS B 1 138 ? -27.814 -2.388  35.396  1   41.292 ? 130  LYS B CE  1 
ATOM   5099 N  NZ  . LYS B 1 138 ? -29.054 -2.151  36.147  1   52.26  ? 130  LYS B NZ  1 
ATOM   5100 N  N   . SER B 1 139 ? -25.102 -2.746  30.724  1   14.659 ? 131  SER B N   1 
ATOM   5101 C  CA  . SER B 1 139 ? -25.822 -3.256  29.562  1   13.962 ? 131  SER B CA  1 
ATOM   5102 C  C   . SER B 1 139 ? -27.22  -2.631  29.443  1   14.983 ? 131  SER B C   1 
ATOM   5103 O  O   . SER B 1 139 ? -27.97  -2.564  30.434  1   16.648 ? 131  SER B O   1 
ATOM   5104 C  CB  . SER B 1 139 ? -25.912 -4.742  29.644  1   14.436 ? 131  SER B CB  1 
ATOM   5105 O  OG  . SER B 1 139 ? -26.755 -5.319  28.642  1   14.673 ? 131  SER B OG  1 
ATOM   5106 N  N   . MET B 1 140 ? -27.552 -2.169  28.214  1   14.55  ? 132  MET B N   1 
ATOM   5107 C  CA  . MET B 1 140 ? -28.851 -1.522  27.932  1   14.824 ? 132  MET B CA  1 
ATOM   5108 C  C   . MET B 1 140 ? -29.485 -2.103  26.666  1   14.98  ? 132  MET B C   1 
ATOM   5109 O  O   . MET B 1 140 ? -30.509 -1.57   26.229  1   16.411 ? 132  MET B O   1 
ATOM   5110 C  CB  . MET B 1 140 ? -28.657 -0.004  27.797  1   18.349 ? 132  MET B CB  1 
ATOM   5111 C  CG  . MET B 1 140 ? -28.118 0.54    29.102  1   21.605 ? 132  MET B CG  1 
ATOM   5112 S  SD  . MET B 1 140 ? -28.188 2.316   29.213  1   26.64  ? 132  MET B SD  1 
ATOM   5113 C  CE  . MET B 1 140 ? -29.967 2.672   29.272  1   19.487 ? 132  MET B CE  1 
ATOM   5114 N  N   . TYR B 1 141 ? -28.918 -3.165  26.107  1   13.864 ? 133  TYR B N   1 
ATOM   5115 C  CA  . TYR B 1 141 ? -29.371 -3.762  24.864  1   14.989 ? 133  TYR B CA  1 
ATOM   5116 C  C   . TYR B 1 141 ? -29.589 -5.243  25.064  1   15.298 ? 133  TYR B C   1 
ATOM   5117 O  O   . TYR B 1 141 ? -28.884 -5.875  25.867  1   14.85  ? 133  TYR B O   1 
ATOM   5118 C  CB  . TYR B 1 141 ? -28.409 -3.487  23.706  1   15.886 ? 133  TYR B CB  1 
ATOM   5119 C  CG  . TYR B 1 141 ? -28.347 -2.024  23.283  1   14.316 ? 133  TYR B CG  1 
ATOM   5120 C  CD1 . TYR B 1 141 ? -27.625 -1.034  23.986  1   14.351 ? 133  TYR B CD1 1 
ATOM   5121 C  CD2 . TYR B 1 141 ? -29.042 -1.622  22.122  1   14.907 ? 133  TYR B CD2 1 
ATOM   5122 C  CE1 . TYR B 1 141 ? -27.603 0.288   23.584  1   13.167 ? 133  TYR B CE1 1 
ATOM   5123 C  CE2 . TYR B 1 141 ? -28.992 -0.302  21.688  1   14.375 ? 133  TYR B CE2 1 
ATOM   5124 C  CZ  . TYR B 1 141 ? -28.295 0.655   22.42   1   13.637 ? 133  TYR B CZ  1 
ATOM   5125 O  OH  . TYR B 1 141 ? -28.17  1.969   22.056  1   16.061 ? 133  TYR B OH  1 
ATOM   5126 N  N   . GLY B 1 142 ? -30.577 -5.781  24.317  1   14.722 ? 134  GLY B N   1 
ATOM   5127 C  CA  . GLY B 1 142 ? -30.972 -7.171  24.461  1   14.762 ? 134  GLY B CA  1 
ATOM   5128 C  C   . GLY B 1 142 ? -30.481 -8.03   23.319  1   16.299 ? 134  GLY B C   1 
ATOM   5129 O  O   . GLY B 1 142 ? -29.274 -8.009  23.025  1   16.123 ? 134  GLY B O   1 
ATOM   5130 N  N   . LEU B 1 143 ? -31.428 -8.74   22.678  1   14.372 ? 135  LEU B N   1 
ATOM   5131 C  CA  . LEU B 1 143 ? -31.127 -9.694  21.606  1   14.728 ? 135  LEU B CA  1 
ATOM   5132 C  C   . LEU B 1 143 ? -30.625 -8.995  20.348  1   14.668 ? 135  LEU B C   1 
ATOM   5133 O  O   . LEU B 1 143 ? -30.997 -7.851  20.046  1   15.543 ? 135  LEU B O   1 
ATOM   5134 C  CB  . LEU B 1 143 ? -32.381 -10.514 21.252  1   15.413 ? 135  LEU B CB  1 
ATOM   5135 C  CG  . LEU B 1 143 ? -33.037 -11.213 22.456  1   15.35  ? 135  LEU B CG  1 
ATOM   5136 C  CD1 . LEU B 1 143 ? -34.217 -11.979 21.834  1   18.043 ? 135  LEU B CD1 1 
ATOM   5137 C  CD2 . LEU B 1 143 ? -32.128 -12.186 23.217  1   18.751 ? 135  LEU B CD2 1 
ATOM   5138 N  N   . TYR B 1 144 ? -29.836 -9.782  19.588  1   16.212 ? 136  TYR B N   1 
ATOM   5139 C  CA  . TYR B 1 144 ? -29.354 -9.362  18.28   1   15.388 ? 136  TYR B CA  1 
ATOM   5140 C  C   . TYR B 1 144 ? -30.544 -8.84   17.45   1   15.801 ? 136  TYR B C   1 
ATOM   5141 O  O   . TYR B 1 144 ? -31.534 -9.544  17.224  1   16.171 ? 136  TYR B O   1 
ATOM   5142 C  CB  . TYR B 1 144 ? -28.774 -10.611 17.598  1   16.977 ? 136  TYR B CB  1 
ATOM   5143 C  CG  . TYR B 1 144 ? -28.226 -10.393 16.194  1   16.724 ? 136  TYR B CG  1 
ATOM   5144 C  CD1 . TYR B 1 144 ? -27.062 -9.618  15.992  1   17.281 ? 136  TYR B CD1 1 
ATOM   5145 C  CD2 . TYR B 1 144 ? -28.879 -10.95  15.081  1   16.631 ? 136  TYR B CD2 1 
ATOM   5146 C  CE1 . TYR B 1 144 ? -26.547 -9.449  14.717  1   16.861 ? 136  TYR B CE1 1 
ATOM   5147 C  CE2 . TYR B 1 144 ? -28.36  -10.764 13.799  1   15.604 ? 136  TYR B CE2 1 
ATOM   5148 C  CZ  . TYR B 1 144 ? -27.216 -9.989  13.621  1   16.225 ? 136  TYR B CZ  1 
ATOM   5149 O  OH  . TYR B 1 144 ? -26.674 -9.806  12.367  1   15.695 ? 136  TYR B OH  1 
ATOM   5150 N  N   . ARG B 1 145 ? -30.432 -7.591  16.996  1   14.777 ? 137  ARG B N   1 
ATOM   5151 C  CA  . ARG B 1 145 ? -31.394 -6.97   16.073  1   13.889 ? 137  ARG B CA  1 
ATOM   5152 C  C   . ARG B 1 145 ? -32.823 -6.983  16.638  1   16.135 ? 137  ARG B C   1 
ATOM   5153 O  O   . ARG B 1 145 ? -33.759 -7.075  15.84   1   14.827 ? 137  ARG B O   1 
ATOM   5154 C  CB  . ARG B 1 145 ? -31.318 -7.661  14.698  1   15.166 ? 137  ARG B CB  1 
ATOM   5155 C  CG  . ARG B 1 145 ? -29.935 -7.387  14.1    1   15.302 ? 137  ARG B CG  1 
ATOM   5156 C  CD  . ARG B 1 145 ? -29.95  -7.796  12.622  1   16.041 ? 137  ARG B CD  1 
ATOM   5157 N  NE  . ARG B 1 145 ? -30.691 -6.754  11.898  1   16.202 ? 137  ARG B NE  1 
ATOM   5158 C  CZ  . ARG B 1 145 ? -30.611 -6.527  10.592  1   17.464 ? 137  ARG B CZ  1 
ATOM   5159 N  NH1 . ARG B 1 145 ? -29.857 -7.327  9.827   1   17.132 ? 137  ARG B NH1 1 
ATOM   5160 N  NH2 . ARG B 1 145 ? -31.271 -5.494  10.09   1   15.623 ? 137  ARG B NH2 1 
ATOM   5161 N  N   . ASN B 1 146 ? -33.031 -6.921  17.951  1   15.193 ? 138  ASN B N   1 
ATOM   5162 C  CA  . ASN B 1 146 ? -34.416 -6.862  18.433  1   15.337 ? 138  ASN B CA  1 
ATOM   5163 C  C   . ASN B 1 146 ? -34.59  -5.675  19.378  1   15.32  ? 138  ASN B C   1 
ATOM   5164 O  O   . ASN B 1 146 ? -34.456 -5.829  20.606  1   16.396 ? 138  ASN B O   1 
ATOM   5165 C  CB  . ASN B 1 146 ? -34.918 -8.158  19.071  1   16.731 ? 138  ASN B CB  1 
ATOM   5166 C  CG  . ASN B 1 146 ? -36.41  -8.006  19.382  1   16.278 ? 138  ASN B CG  1 
ATOM   5167 O  OD1 . ASN B 1 146 ? -36.977 -6.912  19.211  1   16.49  ? 138  ASN B OD1 1 
ATOM   5168 N  ND2 . ASN B 1 146 ? -37.026 -9.059  19.89   1   15.717 ? 138  ASN B ND2 1 
ATOM   5169 N  N   . PRO B 1 147 ? -34.885 -4.466  18.884  1   16.244 ? 139  PRO B N   1 
ATOM   5170 C  CA  . PRO B 1 147 ? -35.15  -3.295  19.721  1   15.125 ? 139  PRO B CA  1 
ATOM   5171 C  C   . PRO B 1 147 ? -36.206 -3.445  20.823  1   16.097 ? 139  PRO B C   1 
ATOM   5172 O  O   . PRO B 1 147 ? -36.135 -2.734  21.831  1   16.319 ? 139  PRO B O   1 
ATOM   5173 C  CB  . PRO B 1 147 ? -35.567 -2.216  18.687  1   16.448 ? 139  PRO B CB  1 
ATOM   5174 C  CG  . PRO B 1 147 ? -34.769 -2.638  17.463  1   17.385 ? 139  PRO B CG  1 
ATOM   5175 C  CD  . PRO B 1 147 ? -34.874 -4.129  17.445  1   17.5   ? 139  PRO B CD  1 
ATOM   5176 N  N   . TYR B 1 148 ? -37.159 -4.387  20.623  1   16.11  ? 140  TYR B N   1 
ATOM   5177 C  CA  . TYR B 1 148 ? -38.197 -4.611  21.632  1   16.812 ? 140  TYR B CA  1 
ATOM   5178 C  C   . TYR B 1 148 ? -37.581 -5.225  22.894  1   18.03  ? 140  TYR B C   1 
ATOM   5179 O  O   . TYR B 1 148 ? -38.238 -5.218  23.942  1   20.266 ? 140  TYR B O   1 
ATOM   5180 C  CB  . TYR B 1 148 ? -39.35  -5.471  21.08   1   15.622 ? 140  TYR B CB  1 
ATOM   5181 C  CG  . TYR B 1 148 ? -40.044 -4.73   19.938  1   17.606 ? 140  TYR B CG  1 
ATOM   5182 C  CD1 . TYR B 1 148 ? -40.895 -3.638  20.179  1   16.947 ? 140  TYR B CD1 1 
ATOM   5183 C  CD2 . TYR B 1 148 ? -39.757 -5.098  18.626  1   17.776 ? 140  TYR B CD2 1 
ATOM   5184 C  CE1 . TYR B 1 148 ? -41.482 -2.952  19.127  1   18.174 ? 140  TYR B CE1 1 
ATOM   5185 C  CE2 . TYR B 1 148 ? -40.276 -4.365  17.566  1   18.446 ? 140  TYR B CE2 1 
ATOM   5186 C  CZ  . TYR B 1 148 ? -41.142 -3.313  17.834  1   18.058 ? 140  TYR B CZ  1 
ATOM   5187 O  OH  . TYR B 1 148 ? -41.694 -2.615  16.785  1   17.684 ? 140  TYR B OH  1 
ATOM   5188 N  N   . THR B 1 149 ? -36.338 -5.706  22.81   1   15.385 ? 141  THR B N   1 
ATOM   5189 C  CA  . THR B 1 149 ? -35.651 -6.275  23.971  1   15.44  ? 141  THR B CA  1 
ATOM   5190 C  C   . THR B 1 149 ? -34.516 -5.35   24.449  1   15.847 ? 141  THR B C   1 
ATOM   5191 O  O   . THR B 1 149 ? -33.731 -5.77   25.313  1   14.975 ? 141  THR B O   1 
ATOM   5192 C  CB  . THR B 1 149 ? -35.109 -7.675  23.665  1   15.101 ? 141  THR B CB  1 
ATOM   5193 O  OG1 . THR B 1 149 ? -34.06  -7.657  22.67   1   15.861 ? 141  THR B OG1 1 
ATOM   5194 C  CG2 . THR B 1 149 ? -36.234 -8.566  23.142  1   17.094 ? 141  THR B CG2 1 
ATOM   5195 N  N   . HIS B 1 150 ? -34.402 -4.113  23.936  1   15.365 ? 142  HIS B N   1 
ATOM   5196 C  CA  . HIS B 1 150 ? -33.438 -3.152  24.476  1   15.228 ? 142  HIS B CA  1 
ATOM   5197 C  C   . HIS B 1 150 ? -34.13  -2.285  25.52   1   17.603 ? 142  HIS B C   1 
ATOM   5198 O  O   . HIS B 1 150 ? -35.371 -2.278  25.647  1   17.901 ? 142  HIS B O   1 
ATOM   5199 C  CB  . HIS B 1 150 ? -32.895 -2.191  23.401  1   15.582 ? 142  HIS B CB  1 
ATOM   5200 C  CG  . HIS B 1 150 ? -32.303 -2.91   22.23   1   15.828 ? 142  HIS B CG  1 
ATOM   5201 N  ND1 . HIS B 1 150 ? -31.788 -4.189  22.271  1   15.032 ? 142  HIS B ND1 1 
ATOM   5202 C  CD2 . HIS B 1 150 ? -32.141 -2.437  20.981  1   15.102 ? 142  HIS B CD2 1 
ATOM   5203 C  CE1 . HIS B 1 150 ? -31.343 -4.504  21.063  1   15.904 ? 142  HIS B CE1 1 
ATOM   5204 N  NE2 . HIS B 1 150 ? -31.567 -3.447  20.24   1   14.953 ? 142  HIS B NE2 1 
ATOM   5205 N  N   . HIS B 1 151 ? -33.318 -1.595  26.328  1   14.923 ? 143  HIS B N   1 
ATOM   5206 C  CA  . HIS B 1 151 ? -33.826 -0.712  27.361  1   14.242 ? 143  HIS B CA  1 
ATOM   5207 C  C   . HIS B 1 151 ? -34.698 0.372   26.724  1   17.613 ? 143  HIS B C   1 
ATOM   5208 O  O   . HIS B 1 151 ? -34.37  0.911   25.681  1   16.626 ? 143  HIS B O   1 
ATOM   5209 C  CB  . HIS B 1 151 ? -32.613 -0.1    28.093  1   13.712 ? 143  HIS B CB  1 
ATOM   5210 C  CG  . HIS B 1 151 ? -32.97  0.76    29.256  1   13.981 ? 143  HIS B CG  1 
ATOM   5211 N  ND1 . HIS B 1 151 ? -32.6   0.526   30.58   1   16.736 ? 143  HIS B ND1 1 
ATOM   5212 C  CD2 . HIS B 1 151 ? -33.5   1.996   29.212  1   12.728 ? 143  HIS B CD2 1 
ATOM   5213 C  CE1 . HIS B 1 151 ? -32.932 1.594   31.298  1   12.313 ? 143  HIS B CE1 1 
ATOM   5214 N  NE2 . HIS B 1 151 ? -33.481 2.488   30.489  1   16.986 ? 143  HIS B NE2 1 
ATOM   5215 N  N   . PRO B 1 152 ? -35.847 0.739   27.312  1   15.061 ? 144  PRO B N   1 
ATOM   5216 C  CA  . PRO B 1 152 ? -36.703 1.795   26.759  1   16.219 ? 144  PRO B CA  1 
ATOM   5217 C  C   . PRO B 1 152 ? -36.006 3.073   26.307  1   17.214 ? 144  PRO B C   1 
ATOM   5218 O  O   . PRO B 1 152 ? -36.383 3.647   25.282  1   19.965 ? 144  PRO B O   1 
ATOM   5219 C  CB  . PRO B 1 152 ? -37.681 2.094   27.935  1   17.177 ? 144  PRO B CB  1 
ATOM   5220 C  CG  . PRO B 1 152 ? -37.849 0.726   28.538  1   16.378 ? 144  PRO B CG  1 
ATOM   5221 C  CD  . PRO B 1 152 ? -36.412 0.113   28.534  1   15.704 ? 144  PRO B CD  1 
ATOM   5222 N  N   . CYS B 1 153 ? -34.983 3.507   27.058  1   16.319 ? 145  CYS B N   1 
ATOM   5223 C  CA  . CYS B 1 153 ? -34.32  4.767   26.72   1   18.49  ? 145  CYS B CA  1 
ATOM   5224 C  C   . CYS B 1 153 ? -33.506 4.666   25.425  1   16.903 ? 145  CYS B C   1 
ATOM   5225 O  O   . CYS B 1 153 ? -33.194 5.726   24.881  1   21.368 ? 145  CYS B O   1 
ATOM   5226 C  CB  . CYS B 1 153 ? -33.334 5.138   27.814  1   22.353 ? 145  CYS B CB  1 
ATOM   5227 S  SG  . CYS B 1 153 ? -34.146 5.769   29.304  1   35.686 ? 145  CYS B SG  1 
ATOM   5228 N  N   . VAL B 1 154 ? -33.188 3.455   24.987  1   15.772 ? 146  VAL B N   1 
ATOM   5229 C  CA  . VAL B 1 154 ? -32.326 3.314   23.797  1   16.881 ? 146  VAL B CA  1 
ATOM   5230 C  C   . VAL B 1 154 ? -33.038 2.614   22.632  1   18.775 ? 146  VAL B C   1 
ATOM   5231 O  O   . VAL B 1 154 ? -32.392 2.312   21.621  1   17.538 ? 146  VAL B O   1 
ATOM   5232 C  CB  . VAL B 1 154 ? -30.985 2.599   24.089  1   17.718 ? 146  VAL B CB  1 
ATOM   5233 C  CG1 . VAL B 1 154 ? -30.277 3.319   25.228  1   21.204 ? 146  VAL B CG1 1 
ATOM   5234 C  CG2 . VAL B 1 154 ? -31.156 1.111   24.413  1   19.901 ? 146  VAL B CG2 1 
ATOM   5235 N  N   . ARG B 1 155 ? -34.349 2.346   22.739  1   17.971 ? 147  ARG B N   1 
ATOM   5236 C  CA  . ARG B 1 155 ? -35.024 1.569   21.718  1   19.736 ? 147  ARG B CA  1 
ATOM   5237 C  C   . ARG B 1 155 ? -34.947 2.251   20.351  1   17.952 ? 147  ARG B C   1 
ATOM   5238 O  O   . ARG B 1 155 ? -34.883 1.51    19.371  1   18.599 ? 147  ARG B O   1 
ATOM   5239 C  CB  . ARG B 1 155 ? -36.478 1.383   22.169  1   19.706 ? 147  ARG B CB  1 
ATOM   5240 C  CG  . ARG B 1 155 ? -37.145 0.319   21.316  1   24.434 ? 147  ARG B CG  1 
ATOM   5241 C  CD  . ARG B 1 155 ? -38.351 -0.319  22.006  1   26.985 ? 147  ARG B CD  1 
ATOM   5242 N  NE  . ARG B 1 155 ? -37.911 -1.081  23.188  1   33.221 ? 147  ARG B NE  1 
ATOM   5243 C  CZ  . ARG B 1 155 ? -38.523 -1.073  24.334  1   31.73  ? 147  ARG B CZ  1 
ATOM   5244 N  NH1 . ARG B 1 155 ? -39.763 -0.574  24.4    1   33.556 ? 147  ARG B NH1 1 
ATOM   5245 N  NH2 . ARG B 1 155 ? -37.951 -1.649  25.367  1   36.226 ? 147  ARG B NH2 1 
ATOM   5246 N  N   . GLN B 1 156 ? -34.938 3.598   20.347  1   18.136 ? 148  GLN B N   1 
ATOM   5247 C  CA  . GLN B 1 156 ? -34.913 4.343   19.105  1   19.899 ? 148  GLN B CA  1 
ATOM   5248 C  C   . GLN B 1 156 ? -33.502 4.828   18.74   1   20.788 ? 148  GLN B C   1 
ATOM   5249 O  O   . GLN B 1 156 ? -33.356 5.831   18.065  1   22.209 ? 148  GLN B O   1 
ATOM   5250 C  CB  . GLN B 1 156 ? -36.044 5.373   19.095  1   20.937 ? 148  GLN B CB  1 
ATOM   5251 C  CG  . GLN B 1 156 ? -36.593 5.641   17.691  1   24.768 ? 148  GLN B CG  1 
ATOM   5252 C  CD  . GLN B 1 156 ? -37.856 6.482   17.697  1   33.164 ? 148  GLN B CD  1 
ATOM   5253 O  OE1 . GLN B 1 156 ? -38.196 7.129   16.697  1   35.857 ? 148  GLN B OE1 1 
ATOM   5254 N  NE2 . GLN B 1 156 ? -38.567 6.488   18.819  1   27.53  ? 148  GLN B NE2 1 
ATOM   5255 N  N   . THR B 1 157 ? -32.473 4.052   19.107  1   18.493 ? 149  THR B N   1 
ATOM   5256 C  CA  . THR B 1 157 ? -31.103 4.377   18.753  1   16.017 ? 149  THR B CA  1 
ATOM   5257 C  C   . THR B 1 157 ? -30.715 3.47    17.593  1   15.722 ? 149  THR B C   1 
ATOM   5258 O  O   . THR B 1 157 ? -31.404 2.504   17.259  1   17.166 ? 149  THR B O   1 
ATOM   5259 C  CB  . THR B 1 157 ? -30.116 4.13    19.904  1   14.522 ? 149  THR B CB  1 
ATOM   5260 O  OG1 . THR B 1 157 ? -30.162 2.75    20.308  1   16.391 ? 149  THR B OG1 1 
ATOM   5261 C  CG2 . THR B 1 157 ? -30.36  5.11    21.029  1   16.305 ? 149  THR B CG2 1 
ATOM   5262 N  N   . VAL B 1 158 ? -29.575 3.819   16.961  1   15.511 ? 150  VAL B N   1 
ATOM   5263 C  CA  . VAL B 1 158 ? -28.862 2.847   16.124  1   15.103 ? 150  VAL B CA  1 
ATOM   5264 C  C   . VAL B 1 158 ? -28.252 1.791   17.044  1   13.635 ? 150  VAL B C   1 
ATOM   5265 O  O   . VAL B 1 158 ? -27.465 2.157   17.919  1   14.566 ? 150  VAL B O   1 
ATOM   5266 C  CB  . VAL B 1 158 ? -27.814 3.592   15.27   1   14.32  ? 150  VAL B CB  1 
ATOM   5267 C  CG1 . VAL B 1 158 ? -26.819 2.62    14.604  1   15.656 ? 150  VAL B CG1 1 
ATOM   5268 C  CG2 . VAL B 1 158 ? -28.579 4.374   14.199  1   15.987 ? 150  VAL B CG2 1 
ATOM   5269 N  N   . GLU B 1 159 ? -28.629 0.521   16.844  1   14.355 ? 151  GLU B N   1 
ATOM   5270 C  CA  . GLU B 1 159 ? -28.262 -0.563  17.746  1   13.991 ? 151  GLU B CA  1 
ATOM   5271 C  C   . GLU B 1 159 ? -27.015 -1.319  17.265  1   14.931 ? 151  GLU B C   1 
ATOM   5272 O  O   . GLU B 1 159 ? -26.573 -2.228  17.941  1   15.277 ? 151  GLU B O   1 
ATOM   5273 C  CB  . GLU B 1 159 ? -29.433 -1.536  17.927  1   15.422 ? 151  GLU B CB  1 
ATOM   5274 C  CG  . GLU B 1 159 ? -29.956 -2.027  16.564  1   17.884 ? 151  GLU B CG  1 
ATOM   5275 C  CD  . GLU B 1 159 ? -30.523 -3.415  16.506  1   17.522 ? 151  GLU B CD  1 
ATOM   5276 O  OE1 . GLU B 1 159 ? -30.821 -3.975  17.57   1   16.646 ? 151  GLU B OE1 1 
ATOM   5277 O  OE2 . GLU B 1 159 ? -30.614 -4.015  15.412  1   18.633 ? 151  GLU B OE2 1 
ATOM   5278 N  N   . SER B 1 160 ? -26.444 -0.92   16.118  1   13.728 ? 152  SER B N   1 
ATOM   5279 C  CA  . SER B 1 160 ? -25.263 -1.583  15.58   1   13.126 ? 152  SER B CA  1 
ATOM   5280 C  C   . SER B 1 160 ? -24.094 -1.56   16.582  1   12.692 ? 152  SER B C   1 
ATOM   5281 O  O   . SER B 1 160 ? -23.756 -0.521  17.114  1   13.506 ? 152  SER B O   1 
ATOM   5282 C  CB  . SER B 1 160 ? -24.875 -0.877  14.319  1   13.167 ? 152  SER B CB  1 
ATOM   5283 O  OG  . SER B 1 160 ? -23.616 -1.383  13.894  1   14.084 ? 152  SER B OG  1 
ATOM   5284 N  N   . THR B 1 161 ? -23.437 -2.715  16.678  1   13.607 ? 153  THR B N   1 
ATOM   5285 C  CA  . THR B 1 161 ? -22.167 -2.807  17.39   1   12.942 ? 153  THR B CA  1 
ATOM   5286 C  C   . THR B 1 161 ? -20.97  -2.773  16.434  1   13.483 ? 153  THR B C   1 
ATOM   5287 O  O   . THR B 1 161 ? -19.821 -2.893  16.877  1   13.133 ? 153  THR B O   1 
ATOM   5288 C  CB  . THR B 1 161 ? -22.116 -4.074  18.244  1   12.846 ? 153  THR B CB  1 
ATOM   5289 O  OG1 . THR B 1 161 ? -22.386 -5.198  17.396  1   13.905 ? 153  THR B OG1 1 
ATOM   5290 C  CG2 . THR B 1 161 ? -23.048 -3.984  19.45   1   13.957 ? 153  THR B CG2 1 
ATOM   5291 N  N   . ALA B 1 162 ? -21.203 -2.546  15.121  1   12.812 ? 154  ALA B N   1 
ATOM   5292 C  CA  . ALA B 1 162 ? -20.11  -2.228  14.183  1   14.056 ? 154  ALA B CA  1 
ATOM   5293 C  C   . ALA B 1 162 ? -18.921 -3.179  14.348  1   12.909 ? 154  ALA B C   1 
ATOM   5294 O  O   . ALA B 1 162 ? -17.772 -2.739  14.558  1   14.186 ? 154  ALA B O   1 
ATOM   5295 C  CB  . ALA B 1 162 ? -19.727 -0.749  14.292  1   15.324 ? 154  ALA B CB  1 
ATOM   5296 N  N   . ASN B 1 163 ? -19.212 -4.487  14.244  1   13.46  ? 155  ASN B N   1 
ATOM   5297 C  CA  . ASN B 1 163 ? -18.264 -5.483  14.742  1   14.173 ? 155  ASN B CA  1 
ATOM   5298 C  C   . ASN B 1 163 ? -17.921 -6.561  13.711  1   15.043 ? 155  ASN B C   1 
ATOM   5299 O  O   . ASN B 1 163 ? -17.283 -7.538  14.125  1   15.145 ? 155  ASN B O   1 
ATOM   5300 C  CB  . ASN B 1 163 ? -18.789 -6.138  16.018  1   12.463 ? 155  ASN B CB  1 
ATOM   5301 C  CG  . ASN B 1 163 ? -19.983 -7.027  15.785  1   12.946 ? 155  ASN B CG  1 
ATOM   5302 O  OD1 . ASN B 1 163 ? -20.605 -6.939  14.717  1   14.045 ? 155  ASN B OD1 1 
ATOM   5303 N  ND2 . ASN B 1 163 ? -20.407 -7.831  16.751  1   14.05  ? 155  ASN B ND2 1 
ATOM   5304 N  N   . THR B 1 164 ? -18.284 -6.402  12.423  1   14.924 ? 156  THR B N   1 
ATOM   5305 C  CA  . THR B 1 164 ? -18.064 -7.536  11.53   1   15.675 ? 156  THR B CA  1 
ATOM   5306 C  C   . THR B 1 164 ? -16.983 -7.348  10.465  1   13.287 ? 156  THR B C   1 
ATOM   5307 O  O   . THR B 1 164 ? -16.324 -8.333  10.137  1   14.323 ? 156  THR B O   1 
ATOM   5308 C  CB  . THR B 1 164 ? -19.331 -8.202  10.985  1   19.224 ? 156  THR B CB  1 
ATOM   5309 O  OG1 . THR B 1 164 ? -19.879 -7.26   10.075  1   21.742 ? 156  THR B OG1 1 
ATOM   5310 C  CG2 . THR B 1 164 ? -20.404 -8.418  12.038  1   17.092 ? 156  THR B CG2 1 
ATOM   5311 N  N   . ASN B 1 165 ? -16.842 -6.14   9.889   1   13.608 ? 157  ASN B N   1 
ATOM   5312 C  CA  . ASN B 1 165 ? -15.813 -5.986  8.844   1   13.106 ? 157  ASN B CA  1 
ATOM   5313 C  C   . ASN B 1 165 ? -15.43  -4.515  8.738   1   13.312 ? 157  ASN B C   1 
ATOM   5314 O  O   . ASN B 1 165 ? -16.061 -3.659  9.359   1   14.55  ? 157  ASN B O   1 
ATOM   5315 C  CB  . ASN B 1 165 ? -16.378 -6.545  7.523   1   13.529 ? 157  ASN B CB  1 
ATOM   5316 C  CG  . ASN B 1 165 ? -15.354 -6.693  6.411   1   14.192 ? 157  ASN B CG  1 
ATOM   5317 O  OD1 . ASN B 1 165 ? -14.131 -6.749  6.635   1   15.859 ? 157  ASN B OD1 1 
ATOM   5318 N  ND2 . ASN B 1 165 ? -15.888 -6.765  5.184   1   15.621 ? 157  ASN B ND2 1 
ATOM   5319 N  N   . VAL B 1 166 ? -14.336 -4.257  7.994   1   13.911 ? 158  VAL B N   1 
ATOM   5320 C  CA  . VAL B 1 166 ? -13.819 -2.897  7.824   1   13.787 ? 158  VAL B CA  1 
ATOM   5321 C  C   . VAL B 1 166 ? -13.523 -2.693  6.349   1   15.258 ? 158  VAL B C   1 
ATOM   5322 O  O   . VAL B 1 166 ? -13.354 -3.655  5.603   1   15.668 ? 158  VAL B O   1 
ATOM   5323 C  CB  . VAL B 1 166 ? -12.547 -2.619  8.654   1   14.615 ? 158  VAL B CB  1 
ATOM   5324 C  CG1 . VAL B 1 166 ? -12.807 -2.774  10.152  1   13.846 ? 158  VAL B CG1 1 
ATOM   5325 C  CG2 . VAL B 1 166 ? -11.406 -3.563  8.269   1   15.572 ? 158  VAL B CG2 1 
ATOM   5326 N  N   . VAL B 1 167 ? -13.437 -1.424  5.969   1   14.896 ? 159  VAL B N   1 
ATOM   5327 C  CA  . VAL B 1 167 ? -13.032 -1.053  4.603   1   15.78  ? 159  VAL B CA  1 
ATOM   5328 C  C   . VAL B 1 167 ? -12.37  0.317   4.652   1   14.899 ? 159  VAL B C   1 
ATOM   5329 O  O   . VAL B 1 167 ? -12.724 1.15    5.486   1   15.607 ? 159  VAL B O   1 
ATOM   5330 C  CB  . VAL B 1 167 ? -14.245 -1.076  3.634   1   16.076 ? 159  VAL B CB  1 
ATOM   5331 C  CG1 . VAL B 1 167 ? -15.292 -0.002  3.945   1   17.429 ? 159  VAL B CG1 1 
ATOM   5332 C  CG2 . VAL B 1 167 ? -13.832 -1.039  2.155   1   17.572 ? 159  VAL B CG2 1 
ATOM   5333 N  N   . MET B 1 168 ? -11.394 0.547   3.756   1   15.562 ? 160  MET B N   1 
ATOM   5334 C  CA  . MET B 1 168 ? -10.916 1.898   3.474   1   16.307 ? 160  MET B CA  1 
ATOM   5335 C  C   . MET B 1 168 ? -11.428 2.282   2.083   1   16.078 ? 160  MET B C   1 
ATOM   5336 O  O   . MET B 1 168 ? -11.045 1.641   1.098   1   17.432 ? 160  MET B O   1 
ATOM   5337 C  CB  . MET B 1 168 ? -9.375  1.899   3.469   1   17.16  ? 160  MET B CB  1 
ATOM   5338 C  CG  . MET B 1 168 ? -8.761  3.254   3.155   1   16.687 ? 160  MET B CG  1 
ATOM   5339 S  SD  . MET B 1 168 ? -8.94   4.482   4.453   1   20.672 ? 160  MET B SD  1 
ATOM   5340 C  CE  . MET B 1 168 ? -7.655  3.952   5.592   1   19.742 ? 160  MET B CE  1 
ATOM   5341 N  N   . HIS B 1 169 ? -12.266 3.316   2.036   1   15.705 ? 161  HIS B N   1 
ATOM   5342 C  CA  . HIS B 1 169 ? -12.838 3.704   0.759   1   16.557 ? 161  HIS B CA  1 
ATOM   5343 C  C   . HIS B 1 169 ? -12.861 5.219   0.735   1   16.186 ? 161  HIS B C   1 
ATOM   5344 O  O   . HIS B 1 169 ? -13.337 5.849   1.668   1   17.326 ? 161  HIS B O   1 
ATOM   5345 C  CB  . HIS B 1 169 ? -14.268 3.157   0.568   1   17.006 ? 161  HIS B CB  1 
ATOM   5346 C  CG  . HIS B 1 169 ? -14.78  3.509   -0.8    1   15.533 ? 161  HIS B CG  1 
ATOM   5347 N  ND1 . HIS B 1 169 ? -14.288 2.817   -1.875  1   15.885 ? 161  HIS B ND1 1 
ATOM   5348 C  CD2 . HIS B 1 169 ? -15.588 4.459   -1.237  1   18.886 ? 161  HIS B CD2 1 
ATOM   5349 C  CE1 . HIS B 1 169 ? -14.866 3.351   -2.982  1   17.668 ? 161  HIS B CE1 1 
ATOM   5350 N  NE2 . HIS B 1 169 ? -15.643 4.343   -2.61   1   19.258 ? 161  HIS B NE2 1 
ATOM   5351 N  N   . ALA B 1 170 ? -12.409 5.808   -0.39   1   17.549 ? 162  ALA B N   1 
ATOM   5352 C  CA  . ALA B 1 170 ? -12.455 7.263   -0.549  1   20.673 ? 162  ALA B CA  1 
ATOM   5353 C  C   . ALA B 1 170 ? -11.727 7.956   0.601   1   17.917 ? 162  ALA B C   1 
ATOM   5354 O  O   . ALA B 1 170 ? -12.138 9.028   1.04    1   21.064 ? 162  ALA B O   1 
ATOM   5355 C  CB  . ALA B 1 170 ? -13.869 7.773   -0.796  1   20.845 ? 162  ALA B CB  1 
ATOM   5356 N  N   . GLY B 1 171 ? -10.632 7.33    1.061   1   17.75  ? 163  GLY B N   1 
ATOM   5357 C  CA  . GLY B 1 171 ? -9.821  7.887   2.146   1   19.202 ? 163  GLY B CA  1 
ATOM   5358 C  C   . GLY B 1 171 ? -10.496 7.837   3.523   1   19.911 ? 163  GLY B C   1 
ATOM   5359 O  O   . GLY B 1 171 ? -10.029 8.514   4.448   1   21.175 ? 163  GLY B O   1 
ATOM   5360 N  N   . ARG B 1 172 ? -11.59  7.067   3.661   1   18.951 ? 164  ARG B N   1 
ATOM   5361 C  CA  . ARG B 1 172 ? -12.333 6.947   4.928   1   17.468 ? 164  ARG B CA  1 
ATOM   5362 C  C   . ARG B 1 172 ? -12.277 5.487   5.382   1   16.016 ? 164  ARG B C   1 
ATOM   5363 O  O   . ARG B 1 172 ? -12.594 4.558   4.624   1   16.81  ? 164  ARG B O   1 
ATOM   5364 C  CB  . ARG B 1 172 ? -13.802 7.346   4.762   1   21.197 ? 164  ARG B CB  1 
ATOM   5365 C  CG  . ARG B 1 172 ? -13.926 8.763   4.227   1   24.105 ? 164  ARG B CG  1 
ATOM   5366 C  CD  . ARG B 1 172 ? -15.348 8.99    4.643   1   30.788 ? 164  ARG B CD  1 
ATOM   5367 N  NE  . ARG B 1 172 ? -15.629 10.317  4.101   1   34.951 ? 164  ARG B NE  1 
ATOM   5368 C  CZ  . ARG B 1 172 ? -15.932 11.394  4.762   1   32.88  ? 164  ARG B CZ  1 
ATOM   5369 N  NH1 . ARG B 1 172 ? -15.994 11.402  6.091   1   25.319 ? 164  ARG B NH1 1 
ATOM   5370 N  NH2 . ARG B 1 172 ? -16.167 12.476  4.031   1   33.013 ? 164  ARG B NH2 1 
ATOM   5371 N  N   . PHE B 1 173 ? -11.889 5.301   6.656   1   16.837 ? 165  PHE B N   1 
ATOM   5372 C  CA  . PHE B 1 173 ? -11.796 3.962   7.247   1   15.311 ? 165  PHE B CA  1 
ATOM   5373 C  C   . PHE B 1 173 ? -13.074 3.695   8.055   1   15.682 ? 165  PHE B C   1 
ATOM   5374 O  O   . PHE B 1 173 ? -13.433 4.471   8.929   1   17.094 ? 165  PHE B O   1 
ATOM   5375 C  CB  . PHE B 1 173 ? -10.546 3.919   8.136   1   17.08  ? 165  PHE B CB  1 
ATOM   5376 C  CG  . PHE B 1 173 ? -10.361 2.559   8.797   1   16.458 ? 165  PHE B CG  1 
ATOM   5377 C  CD1 . PHE B 1 173 ? -10.025 1.448   8.036   1   15.953 ? 165  PHE B CD1 1 
ATOM   5378 C  CD2 . PHE B 1 173 ? -10.576 2.383   10.181  1   17.624 ? 165  PHE B CD2 1 
ATOM   5379 C  CE1 . PHE B 1 173 ? -9.929  0.201   8.627   1   16.134 ? 165  PHE B CE1 1 
ATOM   5380 C  CE2 . PHE B 1 173 ? -10.459 1.118   10.77   1   18.605 ? 165  PHE B CE2 1 
ATOM   5381 C  CZ  . PHE B 1 173 ? -10.114 0.045   9.987   1   17.168 ? 165  PHE B CZ  1 
ATOM   5382 N  N   . LEU B 1 174 ? -13.767 2.626   7.664   1   14.064 ? 166  LEU B N   1 
ATOM   5383 C  CA  . LEU B 1 174 ? -15.123 2.323   8.181   1   15.797 ? 166  LEU B CA  1 
ATOM   5384 C  C   . LEU B 1 174 ? -15.13  0.983   8.931   1   14.817 ? 166  LEU B C   1 
ATOM   5385 O  O   . LEU B 1 174 ? -14.606 -0.005  8.439   1   15.041 ? 166  LEU B O   1 
ATOM   5386 C  CB  . LEU B 1 174 ? -16.08  2.168   6.997   1   16.392 ? 166  LEU B CB  1 
ATOM   5387 C  CG  . LEU B 1 174 ? -16.668 3.426   6.347   1   24.399 ? 166  LEU B CG  1 
ATOM   5388 C  CD1 . LEU B 1 174 ? -15.811 4.632   6.196   1   25.381 ? 166  LEU B CD1 1 
ATOM   5389 C  CD2 . LEU B 1 174 ? -17.36  3.1     5.034   1   22.769 ? 166  LEU B CD2 1 
ATOM   5390 N  N   . ALA B 1 175 ? -15.865 0.967   10.038  1   13.772 ? 167  ALA B N   1 
ATOM   5391 C  CA  . ALA B 1 175 ? -16.281 -0.251  10.719  1   13.433 ? 167  ALA B CA  1 
ATOM   5392 C  C   . ALA B 1 175 ? -17.759 -0.485  10.381  1   14.226 ? 167  ALA B C   1 
ATOM   5393 O  O   . ALA B 1 175 ? -18.549 0.449   10.47   1   14.777 ? 167  ALA B O   1 
ATOM   5394 C  CB  . ALA B 1 175 ? -16.02  -0.105  12.217  1   14.898 ? 167  ALA B CB  1 
ATOM   5395 N  N   . MET B 1 176 ? -18.062 -1.74   10.029  1   13.116 ? 168  MET B N   1 
ATOM   5396 C  CA  . MET B 1 176 ? -19.38  -2.03   9.475   1   13.911 ? 168  MET B CA  1 
ATOM   5397 C  C   . MET B 1 176 ? -20.065 -3.154  10.239  1   14.354 ? 168  MET B C   1 
ATOM   5398 O  O   . MET B 1 176 ? -19.42  -4.095  10.759  1   14.666 ? 168  MET B O   1 
ATOM   5399 C  CB  . MET B 1 176 ? -19.165 -2.528  8.041   1   15.67  ? 168  MET B CB  1 
ATOM   5400 C  CG  . MET B 1 176 ? -18.565 -1.413  7.143   1   14.618 ? 168  MET B CG  1 
ATOM   5401 S  SD  . MET B 1 176 ? -18.282 -1.977  5.439   1   16.575 ? 168  MET B SD  1 
ATOM   5402 C  CE  . MET B 1 176 ? -16.89  -3.094  5.656   1   17.655 ? 168  MET B CE  1 
ATOM   5403 N  N   . LYS B 1 177 ? -21.405 -3.098  10.2    1   14.19  ? 169  LYS B N   1 
ATOM   5404 C  CA  . LYS B 1 177 ? -22.276 -4.2    10.637  1   14.154 ? 169  LYS B CA  1 
ATOM   5405 C  C   . LYS B 1 177 ? -23.617 -3.989  9.92    1   13.284 ? 169  LYS B C   1 
ATOM   5406 O  O   . LYS B 1 177 ? -24.077 -2.861  9.803   1   14.35  ? 169  LYS B O   1 
ATOM   5407 C  CB  . LYS B 1 177 ? -22.439 -4.227  12.169  1   15.416 ? 169  LYS B CB  1 
ATOM   5408 C  CG  . LYS B 1 177 ? -23.214 -5.463  12.678  1   14.585 ? 169  LYS B CG  1 
ATOM   5409 C  CD  . LYS B 1 177 ? -23.448 -5.403  14.188  1   14.744 ? 169  LYS B CD  1 
ATOM   5410 C  CE  . LYS B 1 177 ? -24.076 -6.646  14.766  1   14.904 ? 169  LYS B CE  1 
ATOM   5411 N  NZ  . LYS B 1 177 ? -23.243 -7.841  14.536  1   14.538 ? 169  LYS B NZ  1 
ATOM   5412 N  N   . GLU B 1 178 ? -24.205 -5.085  9.419   1   15.177 ? 170  GLU B N   1 
ATOM   5413 C  CA  . GLU B 1 178 ? -25.286 -5.027  8.43    1   14.656 ? 170  GLU B CA  1 
ATOM   5414 C  C   . GLU B 1 178 ? -26.598 -4.429  8.928   1   16.097 ? 170  GLU B C   1 
ATOM   5415 O  O   . GLU B 1 178 ? -27.525 -4.215  8.111   1   15.649 ? 170  GLU B O   1 
ATOM   5416 C  CB  . GLU B 1 178 ? -25.489 -6.376  7.775   1   14.857 ? 170  GLU B CB  1 
ATOM   5417 C  CG  . GLU B 1 178 ? -26.061 -7.422  8.726   1   15.576 ? 170  GLU B CG  1 
ATOM   5418 C  CD  . GLU B 1 178 ? -25.676 -8.79   8.187   1   18.22  ? 170  GLU B CD  1 
ATOM   5419 O  OE1 . GLU B 1 178 ? -24.516 -9.181  8.359   1   20.185 ? 170  GLU B OE1 1 
ATOM   5420 O  OE2 . GLU B 1 178 ? -26.469 -9.46   7.487   1   19.536 ? 170  GLU B OE2 1 
ATOM   5421 N  N   . ASN B 1 179 ? -26.744 -4.217  10.243  1   14.763 ? 171  ASN B N   1 
ATOM   5422 C  CA  . ASN B 1 179 ? -27.982 -3.651  10.795  1   14.004 ? 171  ASN B CA  1 
ATOM   5423 C  C   . ASN B 1 179 ? -27.904 -2.135  11      1   14.646 ? 171  ASN B C   1 
ATOM   5424 O  O   . ASN B 1 179 ? -28.751 -1.551  11.67   1   15.122 ? 171  ASN B O   1 
ATOM   5425 C  CB  . ASN B 1 179 ? -28.368 -4.344  12.104  1   13.873 ? 171  ASN B CB  1 
ATOM   5426 C  CG  . ASN B 1 179 ? -27.351 -4.156  13.209  1   14.839 ? 171  ASN B CG  1 
ATOM   5427 O  OD1 . ASN B 1 179 ? -26.151 -4.042  12.948  1   15.004 ? 171  ASN B OD1 1 
ATOM   5428 N  ND2 . ASN B 1 179 ? -27.791 -4.265  14.446  1   15.645 ? 171  ASN B ND2 1 
ATOM   5429 N  N   . GLY B 1 180 ? -26.913 -1.468  10.392  1   13.507 ? 172  GLY B N   1 
ATOM   5430 C  CA  . GLY B 1 180 ? -26.753 -0.028  10.494  1   13.73  ? 172  GLY B CA  1 
ATOM   5431 C  C   . GLY B 1 180 ? -25.861 0.455   9.367   1   14.048 ? 172  GLY B C   1 
ATOM   5432 O  O   . GLY B 1 180 ? -25.217 -0.357  8.685   1   14.721 ? 172  GLY B O   1 
ATOM   5433 N  N   . ASN B 1 181 ? -25.789 1.785   9.219   1   14.111 ? 173  ASN B N   1 
ATOM   5434 C  CA  . ASN B 1 181 ? -24.707 2.326   8.394   1   15.078 ? 173  ASN B CA  1 
ATOM   5435 C  C   . ASN B 1 181 ? -23.364 2.205   9.131   1   16.147 ? 173  ASN B C   1 
ATOM   5436 O  O   . ASN B 1 181 ? -23.312 1.842   10.313  1   16.091 ? 173  ASN B O   1 
ATOM   5437 C  CB  . ASN B 1 181 ? -25.036 3.768   7.952   1   14.447 ? 173  ASN B CB  1 
ATOM   5438 C  CG  . ASN B 1 181 ? -25.882 3.77    6.691   1   15.859 ? 173  ASN B CG  1 
ATOM   5439 O  OD1 . ASN B 1 181 ? -25.381 3.351   5.65    1   17.193 ? 173  ASN B OD1 1 
ATOM   5440 N  ND2 . ASN B 1 181 ? -27.172 4.07    6.812   1   16.636 ? 173  ASN B ND2 1 
ATOM   5441 N  N   . ALA B 1 182 ? -22.272 2.482   8.416   1   15.464 ? 174  ALA B N   1 
ATOM   5442 C  CA  . ALA B 1 182 ? -20.919 2.353   8.967   1   15.439 ? 174  ALA B CA  1 
ATOM   5443 C  C   . ALA B 1 182 ? -20.606 3.469   9.944   1   16.089 ? 174  ALA B C   1 
ATOM   5444 O  O   . ALA B 1 182 ? -21.095 4.566   9.83    1   17.174 ? 174  ALA B O   1 
ATOM   5445 C  CB  . ALA B 1 182 ? -19.941 2.409   7.814   1   15.487 ? 174  ALA B CB  1 
ATOM   5446 N  N   . TYR B 1 183 ? -19.655 3.187   10.856  1   14.253 ? 175  TYR B N   1 
ATOM   5447 C  CA  . TYR B 1 183 ? -19.02  4.232   11.652  1   13.943 ? 175  TYR B CA  1 
ATOM   5448 C  C   . TYR B 1 183 ? -17.609 4.444   11.136  1   15.077 ? 175  TYR B C   1 
ATOM   5449 O  O   . TYR B 1 183 ? -16.887 3.487   10.839  1   14.819 ? 175  TYR B O   1 
ATOM   5450 C  CB  . TYR B 1 183 ? -18.918 3.802   13.122  1   14.147 ? 175  TYR B CB  1 
ATOM   5451 C  CG  . TYR B 1 183 ? -20.248 3.842   13.871  1   12.991 ? 175  TYR B CG  1 
ATOM   5452 C  CD1 . TYR B 1 183 ? -21.141 2.754   13.859  1   13.718 ? 175  TYR B CD1 1 
ATOM   5453 C  CD2 . TYR B 1 183 ? -20.576 4.981   14.589  1   14.086 ? 175  TYR B CD2 1 
ATOM   5454 C  CE1 . TYR B 1 183 ? -22.324 2.787   14.605  1   13.399 ? 175  TYR B CE1 1 
ATOM   5455 C  CE2 . TYR B 1 183 ? -21.757 5.019   15.341  1   15.502 ? 175  TYR B CE2 1 
ATOM   5456 C  CZ  . TYR B 1 183 ? -22.628 3.933   15.338  1   15.23  ? 175  TYR B CZ  1 
ATOM   5457 O  OH  . TYR B 1 183 ? -23.767 4.028   16.132  1   14.642 ? 175  TYR B OH  1 
ATOM   5458 N  N   . GLU B 1 184 ? -17.235 5.713   11.015  1   14.537 ? 176  GLU B N   1 
ATOM   5459 C  CA  . GLU B 1 184 ? -15.891 6.012   10.537  1   15.297 ? 176  GLU B CA  1 
ATOM   5460 C  C   . GLU B 1 184 ? -14.939 6.159   11.716  1   15.421 ? 176  GLU B C   1 
ATOM   5461 O  O   . GLU B 1 184 ? -15.318 6.704   12.753  1   16.397 ? 176  GLU B O   1 
ATOM   5462 C  CB  . GLU B 1 184 ? -15.937 7.333   9.753   1   15.256 ? 176  GLU B CB  1 
ATOM   5463 C  CG  . GLU B 1 184 ? -14.586 7.662   9.137   1   16.449 ? 176  GLU B CG  1 
ATOM   5464 C  CD  . GLU B 1 184 ? -14.52  8.927   8.292   1   19.66  ? 176  GLU B CD  1 
ATOM   5465 O  OE1 . GLU B 1 184 ? -15.567 9.561   8.114   1   21.593 ? 176  GLU B OE1 1 
ATOM   5466 O  OE2 . GLU B 1 184 ? -13.417 9.209   7.772   1   20.358 ? 176  GLU B OE2 1 
ATOM   5467 N  N   . MET B 1 185 ? -13.696 5.703   11.51   1   15.508 ? 177  MET B N   1 
ATOM   5468 C  CA  . MET B 1 185 ? -12.645 5.851   12.525  1   15.259 ? 177  MET B CA  1 
ATOM   5469 C  C   . MET B 1 185 ? -11.403 6.462   11.884  1   15.739 ? 177  MET B C   1 
ATOM   5470 O  O   . MET B 1 185 ? -11.16  6.259   10.695  1   16.403 ? 177  MET B O   1 
ATOM   5471 C  CB  . MET B 1 185 ? -12.251 4.493   13.114  1   16.668 ? 177  MET B CB  1 
ATOM   5472 C  CG  . MET B 1 185 ? -13.459 3.714   13.633  1   18.143 ? 177  MET B CG  1 
ATOM   5473 S  SD  . MET B 1 185 ? -13.154 1.969   14.006  1   18.13  ? 177  MET B SD  1 
ATOM   5474 C  CE  . MET B 1 185 ? -12.355 2.088   15.607  1   17.955 ? 177  MET B CE  1 
ATOM   5475 N  N   . ASP B 1 186 ? -10.578 7.128   12.709  1   14.348 ? 178  ASP B N   1 
ATOM   5476 C  CA  . ASP B 1 186 ? -9.273  7.594   12.232  1   15.658 ? 178  ASP B CA  1 
ATOM   5477 C  C   . ASP B 1 186 ? -8.4    6.346   12.063  1   15.335 ? 178  ASP B C   1 
ATOM   5478 O  O   . ASP B 1 186 ? -8.387  5.473   12.941  1   15.8   ? 178  ASP B O   1 
ATOM   5479 C  CB  . ASP B 1 186 ? -8.679  8.552   13.259  1   15.497 ? 178  ASP B CB  1 
ATOM   5480 C  CG  . ASP B 1 186 ? -7.318  9.089   12.837  1   17.588 ? 178  ASP B CG  1 
ATOM   5481 O  OD1 . ASP B 1 186 ? -6.316  8.365   12.937  1   18.221 ? 178  ASP B OD1 1 
ATOM   5482 O  OD2 . ASP B 1 186 ? -7.301  10.209  12.253  1   20.942 ? 178  ASP B OD2 1 
ATOM   5483 N  N   . PRO B 1 187 ? -7.692  6.165   10.921  1   15.653 ? 179  PRO B N   1 
ATOM   5484 C  CA  . PRO B 1 187 ? -6.951  4.911   10.686  1   15.707 ? 179  PRO B CA  1 
ATOM   5485 C  C   . PRO B 1 187 ? -5.654  4.768   11.495  1   16.574 ? 179  PRO B C   1 
ATOM   5486 O  O   . PRO B 1 187 ? -5.079  3.691   11.465  1   17.535 ? 179  PRO B O   1 
ATOM   5487 C  CB  . PRO B 1 187 ? -6.679  4.938   9.157   1   17.833 ? 179  PRO B CB  1 
ATOM   5488 C  CG  . PRO B 1 187 ? -6.571  6.441   8.882   1   17.349 ? 179  PRO B CG  1 
ATOM   5489 C  CD  . PRO B 1 187 ? -7.604  7.132   9.807   1   16.172 ? 179  PRO B CD  1 
ATOM   5490 N  N   . HIS B 1 188 ? -5.263  5.823   12.233  1   15.885 ? 180  HIS B N   1 
ATOM   5491 C  CA  . HIS B 1 188 ? -4.038  5.786   13.02   1   16.389 ? 180  HIS B CA  1 
ATOM   5492 C  C   . HIS B 1 188 ? -4.326  5.699   14.503  1   16.818 ? 180  HIS B C   1 
ATOM   5493 O  O   . HIS B 1 188 ? -3.64   4.926   15.185  1   16.946 ? 180  HIS B O   1 
ATOM   5494 C  CB  . HIS B 1 188 ? -3.167  7.022   12.748  1   17.304 ? 180  HIS B CB  1 
ATOM   5495 C  CG  . HIS B 1 188 ? -3.113  7.328   11.296  1   18.249 ? 180  HIS B CG  1 
ATOM   5496 N  ND1 . HIS B 1 188 ? -2.468  6.523   10.37   1   18.348 ? 180  HIS B ND1 1 
ATOM   5497 C  CD2 . HIS B 1 188 ? -3.649  8.36    10.631  1   18.073 ? 180  HIS B CD2 1 
ATOM   5498 C  CE1 . HIS B 1 188 ? -2.595  7.07    9.164   1   18.431 ? 180  HIS B CE1 1 
ATOM   5499 N  NE2 . HIS B 1 188 ? -3.302  8.177   9.277   1   20.286 ? 180  HIS B NE2 1 
ATOM   5500 N  N   . THR B 1 189 ? -5.262  6.54    14.992  1   15.038 ? 181  THR B N   1 
ATOM   5501 C  CA  . THR B 1 189 ? -5.593  6.523   16.423  1   15.744 ? 181  THR B CA  1 
ATOM   5502 C  C   . THR B 1 189 ? -6.786  5.622   16.703  1   15.435 ? 181  THR B C   1 
ATOM   5503 O  O   . THR B 1 189 ? -7.071  5.337   17.873  1   14.159 ? 181  THR B O   1 
ATOM   5504 C  CB  . THR B 1 189 ? -5.932  7.938   16.909  1   17.83  ? 181  THR B CB  1 
ATOM   5505 O  OG1 . THR B 1 189 ? -7.155  8.283   16.252  1   16.23  ? 181  THR B OG1 1 
ATOM   5506 C  CG2 . THR B 1 189 ? -4.829  8.96    16.624  1   21.441 ? 181  THR B CG2 1 
ATOM   5507 N  N   . LEU B 1 190 ? -7.547  5.27    15.639  1   15.226 ? 182  LEU B N   1 
ATOM   5508 C  CA  . LEU B 1 190 ? -8.792  4.508   15.764  1   15.217 ? 182  LEU B CA  1 
ATOM   5509 C  C   . LEU B 1 190 ? -9.865  5.279   16.523  1   15.951 ? 182  LEU B C   1 
ATOM   5510 O  O   . LEU B 1 190 ? -10.865 4.669   16.905  1   15.277 ? 182  LEU B O   1 
ATOM   5511 C  CB  . LEU B 1 190 ? -8.567  3.086   16.318  1   13.53  ? 182  LEU B CB  1 
ATOM   5512 C  CG  . LEU B 1 190 ? -7.709  2.16    15.431  1   13.176 ? 182  LEU B CG  1 
ATOM   5513 C  CD1 . LEU B 1 190 ? -7.559  0.83    16.136  1   15.141 ? 182  LEU B CD1 1 
ATOM   5514 C  CD2 . LEU B 1 190 ? -8.432  1.911   14.11   1   16.207 ? 182  LEU B CD2 1 
ATOM   5515 N  N   . LYS B 1 191 ? -9.696  6.594   16.704  1   15.025 ? 183  LYS B N   1 
ATOM   5516 C  CA  . LYS B 1 191 ? -10.766 7.4     17.29   1   16.242 ? 183  LYS B CA  1 
ATOM   5517 C  C   . LYS B 1 191 ? -11.987 7.409   16.363  1   14.2   ? 183  LYS B C   1 
ATOM   5518 O  O   . LYS B 1 191 ? -11.825 7.499   15.141  1   16.525 ? 183  LYS B O   1 
ATOM   5519 C  CB  . LYS B 1 191 ? -10.251 8.845   17.438  1   17.498 ? 183  LYS B CB  1 
ATOM   5520 C  CG  . LYS B 1 191 ? -11.242 9.81    18.108  1   21.236 ? 183  LYS B CG  1 
ATOM   5521 C  CD  . LYS B 1 191 ? -10.533 11.023  18.727  1   25.537 ? 183  LYS B CD  1 
ATOM   5522 C  CE  . LYS B 1 191 ? -11.532 11.964  19.435  1   26.205 ? 183  LYS B CE  1 
ATOM   5523 N  NZ  . LYS B 1 191 ? -12.329 11.379  20.529  1   28.559 ? 183  LYS B NZ  1 
ATOM   5524 N  N   . THR B 1 192 ? -13.198 7.32    16.939  1   14.256 ? 184  THR B N   1 
ATOM   5525 C  CA  . THR B 1 192 ? -14.39  7.326   16.098  1   14.304 ? 184  THR B CA  1 
ATOM   5526 C  C   . THR B 1 192 ? -14.659 8.759   15.665  1   15.617 ? 184  THR B C   1 
ATOM   5527 O  O   . THR B 1 192 ? -14.599 9.665   16.47   1   15.033 ? 184  THR B O   1 
ATOM   5528 C  CB  . THR B 1 192 ? -15.55  6.719   16.889  1   14.534 ? 184  THR B CB  1 
ATOM   5529 O  OG1 . THR B 1 192 ? -15.226 5.328   17.05   1   15.653 ? 184  THR B OG1 1 
ATOM   5530 C  CG2 . THR B 1 192 ? -16.855 6.748   16.095  1   14.776 ? 184  THR B CG2 1 
ATOM   5531 N  N   . LEU B 1 193 ? -14.996 8.933   14.381  1   15.519 ? 185  LEU B N   1 
ATOM   5532 C  CA  . LEU B 1 193 ? -15.186 10.263  13.799  1   16.906 ? 185  LEU B CA  1 
ATOM   5533 C  C   . LEU B 1 193 ? -16.64  10.586  13.441  1   17.098 ? 185  LEU B C   1 
ATOM   5534 O  O   . LEU B 1 193 ? -16.976 11.77   13.343  1   19.186 ? 185  LEU B O   1 
ATOM   5535 C  CB  . LEU B 1 193 ? -14.345 10.317  12.52   1   15.8   ? 185  LEU B CB  1 
ATOM   5536 C  CG  . LEU B 1 193 ? -12.842 10.114  12.748  1   17.936 ? 185  LEU B CG  1 
ATOM   5537 C  CD1 . LEU B 1 193 ? -12.092 10.236  11.426  1   16.348 ? 185  LEU B CD1 1 
ATOM   5538 C  CD2 . LEU B 1 193 ? -12.24  11.047  13.78   1   21.192 ? 185  LEU B CD2 1 
ATOM   5539 N  N   . GLY B 1 194 ? -17.479 9.566   13.198  1   16.612 ? 186  GLY B N   1 
ATOM   5540 C  CA  . GLY B 1 194 ? -18.839 9.829   12.755  1   15.495 ? 186  GLY B CA  1 
ATOM   5541 C  C   . GLY B 1 194 ? -19.557 8.586   12.29   1   18.539 ? 186  GLY B C   1 
ATOM   5542 O  O   . GLY B 1 194 ? -19.014 7.492   12.352  1   16.749 ? 186  GLY B O   1 
ATOM   5543 N  N   . TYR B 1 195 ? -20.798 8.817   11.812  1   18.658 ? 187  TYR B N   1 
ATOM   5544 C  CA  . TYR B 1 195 ? -21.688 7.74    11.398  1   17.607 ? 187  TYR B CA  1 
ATOM   5545 C  C   . TYR B 1 195 ? -22.195 8.098   10.005  1   16.249 ? 187  TYR B C   1 
ATOM   5546 O  O   . TYR B 1 195 ? -22.495 9.264   9.721   1   18.259 ? 187  TYR B O   1 
ATOM   5547 C  CB  . TYR B 1 195 ? -22.846 7.657   12.406  1   16.525 ? 187  TYR B CB  1 
ATOM   5548 C  CG  . TYR B 1 195 ? -23.942 6.692   11.985  1   15.907 ? 187  TYR B CG  1 
ATOM   5549 C  CD1 . TYR B 1 195 ? -23.82  5.309   12.222  1   15.727 ? 187  TYR B CD1 1 
ATOM   5550 C  CD2 . TYR B 1 195 ? -25.132 7.151   11.397  1   15.95  ? 187  TYR B CD2 1 
ATOM   5551 C  CE1 . TYR B 1 195 ? -24.798 4.419   11.815  1   16.968 ? 187  TYR B CE1 1 
ATOM   5552 C  CE2 . TYR B 1 195 ? -26.119 6.265   10.972  1   15.348 ? 187  TYR B CE2 1 
ATOM   5553 C  CZ  . TYR B 1 195 ? -25.966 4.899   11.211  1   14.601 ? 187  TYR B CZ  1 
ATOM   5554 O  OH  . TYR B 1 195 ? -26.938 3.992   10.826  1   16.949 ? 187  TYR B OH  1 
ATOM   5555 N  N   . ASN B 1 196 ? -22.336 7.07    9.177   1   15.207 ? 188  ASN B N   1 
ATOM   5556 C  CA  . ASN B 1 196 ? -22.911 7.181   7.831   1   16.226 ? 188  ASN B CA  1 
ATOM   5557 C  C   . ASN B 1 196 ? -22.158 8.245   7.008   1   18.179 ? 188  ASN B C   1 
ATOM   5558 O  O   . ASN B 1 196 ? -22.775 9.201   6.503   1   18.647 ? 188  ASN B O   1 
ATOM   5559 C  CB  . ASN B 1 196 ? -24.417 7.443   7.864   1   16.629 ? 188  ASN B CB  1 
ATOM   5560 C  CG  . ASN B 1 196 ? -25.102 7.256   6.532   1   17.644 ? 188  ASN B CG  1 
ATOM   5561 O  OD1 . ASN B 1 196 ? -24.556 6.706   5.572   1   18.164 ? 188  ASN B OD1 1 
ATOM   5562 N  ND2 . ASN B 1 196 ? -26.373 7.645   6.527   1   16.608 ? 188  ASN B ND2 1 
ATOM   5563 N  N   . PRO B 1 197 ? -20.829 8.14    6.831   1   18.459 ? 189  PRO B N   1 
ATOM   5564 C  CA  . PRO B 1 197 ? -20.079 9.184   6.112   1   21.377 ? 189  PRO B CA  1 
ATOM   5565 C  C   . PRO B 1 197 ? -20.467 9.453   4.663   1   18.965 ? 189  PRO B C   1 
ATOM   5566 O  O   . PRO B 1 197 ? -20.269 10.568  4.184   1   22.656 ? 189  PRO B O   1 
ATOM   5567 C  CB  . PRO B 1 197 ? -18.608 8.728   6.227   1   22.348 ? 189  PRO B CB  1 
ATOM   5568 C  CG  . PRO B 1 197 ? -18.687 7.226   6.381   1   21.194 ? 189  PRO B CG  1 
ATOM   5569 C  CD  . PRO B 1 197 ? -19.933 7.066   7.31    1   18.772 ? 189  PRO B CD  1 
ATOM   5570 N  N   . PHE B 1 198 ? -21.011 8.432   3.993   1   18.811 ? 190  PHE B N   1 
ATOM   5571 C  CA  . PHE B 1 198 ? -21.426 8.571   2.599   1   18.887 ? 190  PHE B CA  1 
ATOM   5572 C  C   . PHE B 1 198 ? -22.885 9.016   2.508   1   20.591 ? 190  PHE B C   1 
ATOM   5573 O  O   . PHE B 1 198 ? -23.416 9.102   1.388   1   20.316 ? 190  PHE B O   1 
ATOM   5574 C  CB  . PHE B 1 198 ? -21.099 7.305   1.794   1   20.047 ? 190  PHE B CB  1 
ATOM   5575 C  CG  . PHE B 1 198 ? -19.622 6.941   1.797   1   18.348 ? 190  PHE B CG  1 
ATOM   5576 C  CD1 . PHE B 1 198 ? -18.664 7.901   1.444   1   18.729 ? 190  PHE B CD1 1 
ATOM   5577 C  CD2 . PHE B 1 198 ? -19.173 5.666   2.163   1   20.43  ? 190  PHE B CD2 1 
ATOM   5578 C  CE1 . PHE B 1 198 ? -17.299 7.599   1.419   1   20.256 ? 190  PHE B CE1 1 
ATOM   5579 C  CE2 . PHE B 1 198 ? -17.79  5.361   2.134   1   20.932 ? 190  PHE B CE2 1 
ATOM   5580 C  CZ  . PHE B 1 198 ? -16.851 6.335   1.769   1   20.539 ? 190  PHE B CZ  1 
ATOM   5581 N  N   . ASN B 1 199 ? -23.563 9.243   3.642   1   19.733 ? 191  ASN B N   1 
ATOM   5582 C  CA  . ASN B 1 199 ? -24.936 9.754   3.703   1   20.813 ? 191  ASN B CA  1 
ATOM   5583 C  C   . ASN B 1 199 ? -25.872 8.877   2.873   1   21.83  ? 191  ASN B C   1 
ATOM   5584 O  O   . ASN B 1 199 ? -26.657 9.385   2.059   1   22.339 ? 191  ASN B O   1 
ATOM   5585 C  CB  . ASN B 1 199 ? -25.036 11.213  3.231   1   24.42  ? 191  ASN B CB  1 
ATOM   5586 C  CG  . ASN B 1 199 ? -24.271 12.156  4.128   1   29.684 ? 191  ASN B CG  1 
ATOM   5587 O  OD1 . ASN B 1 199 ? -24.502 12.186  5.336   1   35.223 ? 191  ASN B OD1 1 
ATOM   5588 N  ND2 . ASN B 1 199 ? -23.364 12.939  3.567   1   39.759 ? 191  ASN B ND2 1 
ATOM   5589 N  N   . LEU B 1 200 ? -25.791 7.548   3.039   1   19.663 ? 192  LEU B N   1 
ATOM   5590 C  CA  . LEU B 1 200 ? -26.703 6.653   2.354   1   20.494 ? 192  LEU B CA  1 
ATOM   5591 C  C   . LEU B 1 200 ? -28.107 6.886   2.899   1   22.073 ? 192  LEU B C   1 
ATOM   5592 O  O   . LEU B 1 200 ? -28.3   7.149   4.087   1   20.477 ? 192  LEU B O   1 
ATOM   5593 C  CB  . LEU B 1 200 ? -26.296 5.191   2.508   1   18.127 ? 192  LEU B CB  1 
ATOM   5594 C  CG  . LEU B 1 200 ? -24.872 4.823   2.06    1   18.805 ? 192  LEU B CG  1 
ATOM   5595 C  CD1 . LEU B 1 200 ? -24.703 3.317   2.131   1   19.514 ? 192  LEU B CD1 1 
ATOM   5596 C  CD2 . LEU B 1 200 ? -24.597 5.31    0.596   1   19.06  ? 192  LEU B CD2 1 
ATOM   5597 N  N   . PRO B 1 201 ? -29.146 6.833   2.032   1   18.35  ? 193  PRO B N   1 
ATOM   5598 C  CA  . PRO B 1 201 ? -30.515 7.028   2.501   1   20.857 ? 193  PRO B CA  1 
ATOM   5599 C  C   . PRO B 1 201 ? -31.205 5.849   3.192   1   23.061 ? 193  PRO B C   1 
ATOM   5600 O  O   . PRO B 1 201 ? -32.295 5.997   3.757   1   24.374 ? 193  PRO B O   1 
ATOM   5601 C  CB  . PRO B 1 201 ? -31.166 7.47    1.149   1   21.87  ? 193  PRO B CB  1 
ATOM   5602 C  CG  . PRO B 1 201 ? -30.484 6.582   0.115   1   23.364 ? 193  PRO B CG  1 
ATOM   5603 C  CD  . PRO B 1 201 ? -29.011 6.739   0.558   1   19.957 ? 193  PRO B CD  1 
ATOM   5604 N  N   A SER B 1 202 ? -30.571 4.676   3.121   0.5 18.81  ? 194  SER B N   1 
ATOM   5605 N  N   B SER B 1 202 ? -30.534 4.694   3.166   0.5 19.18  ? 194  SER B N   1 
ATOM   5606 C  CA  A SER B 1 202 ? -31.045 3.486   3.813   0.5 18.053 ? 194  SER B CA  1 
ATOM   5607 C  CA  B SER B 1 202 ? -30.958 3.452   3.794   0.5 19.041 ? 194  SER B CA  1 
ATOM   5608 C  C   A SER B 1 202 ? -30.68  3.598   5.297   0.5 17.65  ? 194  SER B C   1 
ATOM   5609 C  C   B SER B 1 202 ? -30.625 3.538   5.283   0.5 18.054 ? 194  SER B C   1 
ATOM   5610 O  O   A SER B 1 202 ? -29.798 4.362   5.698   0.5 18.321 ? 194  SER B O   1 
ATOM   5611 O  O   B SER B 1 202 ? -29.681 4.221   5.667   0.5 18.243 ? 194  SER B O   1 
ATOM   5612 C  CB  A SER B 1 202 ? -30.432 2.267   3.175   0.5 17.211 ? 194  SER B CB  1 
ATOM   5613 C  CB  B SER B 1 202 ? -30.182 2.341   3.157   0.5 18.258 ? 194  SER B CB  1 
ATOM   5614 O  OG  A SER B 1 202 ? -29.031 2.43    3.065   0.5 16.767 ? 194  SER B OG  1 
ATOM   5615 O  OG  B SER B 1 202 ? -30.443 1.126   3.826   0.5 19.048 ? 194  SER B OG  1 
ATOM   5616 N  N   . LYS B 1 203 ? -31.393 2.819   6.105   1   16.811 ? 195  LYS B N   1 
ATOM   5617 C  CA  . LYS B 1 203 ? -31.05  2.67    7.532   1   16.174 ? 195  LYS B CA  1 
ATOM   5618 C  C   . LYS B 1 203 ? -29.861 1.737   7.731   1   15.581 ? 195  LYS B C   1 
ATOM   5619 O  O   . LYS B 1 203 ? -29.296 1.698   8.846   1   17.119 ? 195  LYS B O   1 
ATOM   5620 C  CB  . LYS B 1 203 ? -32.271 2.192   8.311   1   18.558 ? 195  LYS B CB  1 
ATOM   5621 C  CG  . LYS B 1 203 ? -33.371 3.237   8.353   1   19.527 ? 195  LYS B CG  1 
ATOM   5622 C  CD  . LYS B 1 203 ? -34.46  2.76    9.3     1   22.177 ? 195  LYS B CD  1 
ATOM   5623 C  CE  . LYS B 1 203 ? -35.765 3.446   9.132   1   29.227 ? 195  LYS B CE  1 
ATOM   5624 N  NZ  . LYS B 1 203 ? -35.82  4.611   9.982   1   29.588 ? 195  LYS B NZ  1 
ATOM   5625 N  N   . THR B 1 204 ? -29.479 0.957   6.71    1   15.919 ? 196  THR B N   1 
ATOM   5626 C  CA  . THR B 1 204 ? -28.48  -0.083  6.824   1   16.707 ? 196  THR B CA  1 
ATOM   5627 C  C   . THR B 1 204 ? -27.51  -0.011  5.656   1   18.322 ? 196  THR B C   1 
ATOM   5628 O  O   . THR B 1 204 ? -27.839 0.476   4.548   1   17.37  ? 196  THR B O   1 
ATOM   5629 C  CB  . THR B 1 204 ? -29.151 -1.446  6.843   1   15.809 ? 196  THR B CB  1 
ATOM   5630 O  OG1 . THR B 1 204 ? -29.831 -1.577  5.579   1   17.454 ? 196  THR B OG1 1 
ATOM   5631 C  CG2 . THR B 1 204 ? -30.16  -1.541  7.975   1   17.08  ? 196  THR B CG2 1 
ATOM   5632 N  N   . MET B 1 205 ? -26.336 -0.603  5.9     1   15.828 ? 197  MET B N   1 
ATOM   5633 C  CA  . MET B 1 205 ? -25.388 -0.893  4.854   1   16.836 ? 197  MET B CA  1 
ATOM   5634 C  C   . MET B 1 205 ? -24.826 -2.265  5.154   1   16.825 ? 197  MET B C   1 
ATOM   5635 O  O   . MET B 1 205 ? -24.473 -2.539  6.306   1   17.066 ? 197  MET B O   1 
ATOM   5636 C  CB  . MET B 1 205 ? -24.279 0.172   4.795   1   14.462 ? 197  MET B CB  1 
ATOM   5637 C  CG  . MET B 1 205 ? -23.404 -0.049  3.581   1   16.238 ? 197  MET B CG  1 
ATOM   5638 S  SD  . MET B 1 205 ? -21.927 0.977   3.468   1   16.863 ? 197  MET B SD  1 
ATOM   5639 C  CE  . MET B 1 205 ? -20.904 0.06    4.644   1   16.914 ? 197  MET B CE  1 
ATOM   5640 N  N   . THR B 1 206 ? -24.657 -3.097  4.13    1   17.218 ? 198  THR B N   1 
ATOM   5641 C  CA  . THR B 1 206 ? -23.987 -4.383  4.263   1   15.639 ? 198  THR B CA  1 
ATOM   5642 C  C   . THR B 1 206 ? -22.601 -4.164  4.866   1   15.921 ? 198  THR B C   1 
ATOM   5643 O  O   . THR B 1 206 ? -21.975 -3.126  4.618   1   16.922 ? 198  THR B O   1 
ATOM   5644 C  CB  . THR B 1 206 ? -23.887 -5.09   2.897   1   15.472 ? 198  THR B CB  1 
ATOM   5645 O  OG1 . THR B 1 206 ? -23.32  -6.371  3.072   1   16.441 ? 198  THR B OG1 1 
ATOM   5646 C  CG2 . THR B 1 206 ? -23.026 -4.33   1.89    1   17.365 ? 198  THR B CG2 1 
ATOM   5647 N  N   . ALA B 1 207 ? -22.159 -5.196  5.577   1   15.666 ? 199  ALA B N   1 
ATOM   5648 C  CA  . ALA B 1 207 ? -20.77  -5.207  6       1   15.972 ? 199  ALA B CA  1 
ATOM   5649 C  C   . ALA B 1 207 ? -19.912 -5.975  5.008   1   17.501 ? 199  ALA B C   1 
ATOM   5650 O  O   . ALA B 1 207 ? -18.72  -6.156  5.256   1   17.293 ? 199  ALA B O   1 
ATOM   5651 C  CB  . ALA B 1 207 ? -20.67  -5.816  7.39    1   19.032 ? 199  ALA B CB  1 
ATOM   5652 N  N   . HIS B 1 208 ? -20.509 -6.414  3.864   1   15.209 ? 200  HIS B N   1 
ATOM   5653 C  CA  . HIS B 1 208 ? -19.753 -7.103  2.821   1   15.878 ? 200  HIS B CA  1 
ATOM   5654 C  C   . HIS B 1 208 ? -19.856 -6.314  1.508   1   15.921 ? 200  HIS B C   1 
ATOM   5655 O  O   . HIS B 1 208 ? -20.16  -6.922  0.479   1   17.577 ? 200  HIS B O   1 
ATOM   5656 C  CB  . HIS B 1 208 ? -20.208 -8.562  2.725   1   17.699 ? 200  HIS B CB  1 
ATOM   5657 C  CG  . HIS B 1 208 ? -19.643 -9.426  3.799   1   16.157 ? 200  HIS B CG  1 
ATOM   5658 N  ND1 . HIS B 1 208 ? -18.292 -9.679  3.796   1   16.921 ? 200  HIS B ND1 1 
ATOM   5659 C  CD2 . HIS B 1 208 ? -20.15  -10.037 4.888   1   16.786 ? 200  HIS B CD2 1 
ATOM   5660 C  CE1 . HIS B 1 208 ? -17.955 -10.408 4.84    1   17.594 ? 200  HIS B CE1 1 
ATOM   5661 N  NE2 . HIS B 1 208 ? -19.084 -10.66  5.522   1   16.293 ? 200  HIS B NE2 1 
ATOM   5662 N  N   . PRO B 1 209 ? -19.564 -5.006  1.453   1   14.897 ? 201  PRO B N   1 
ATOM   5663 C  CA  . PRO B 1 209 ? -19.47  -4.325  0.156   1   15.667 ? 201  PRO B CA  1 
ATOM   5664 C  C   . PRO B 1 209 ? -18.197 -4.815  -0.535  1   15.23  ? 201  PRO B C   1 
ATOM   5665 O  O   . PRO B 1 209 ? -17.289 -5.366  0.079   1   17.169 ? 201  PRO B O   1 
ATOM   5666 C  CB  . PRO B 1 209 ? -19.379 -2.895  0.589   1   16.101 ? 201  PRO B CB  1 
ATOM   5667 C  CG  . PRO B 1 209 ? -18.493 -2.933  1.851   1   16.543 ? 201  PRO B CG  1 
ATOM   5668 C  CD  . PRO B 1 209 ? -19.066 -4.118  2.548   1   15.278 ? 201  PRO B CD  1 
ATOM   5669 N  N   . LYS B 1 210 ? -18.13  -4.571  -1.853  1   16.813 ? 202  LYS B N   1 
ATOM   5670 C  CA  . LYS B 1 210 ? -16.967 -5.04   -2.608  1   15.713 ? 202  LYS B CA  1 
ATOM   5671 C  C   . LYS B 1 210 ? -16.375 -3.851  -3.361  1   16.534 ? 202  LYS B C   1 
ATOM   5672 O  O   . LYS B 1 210 ? -17.138 -3.074  -3.935  1   18.424 ? 202  LYS B O   1 
ATOM   5673 C  CB  . LYS B 1 210 ? -17.408 -6.112  -3.641  1   16.414 ? 202  LYS B CB  1 
ATOM   5674 C  CG  . LYS B 1 210 ? -18.252 -7.279  -3.058  1   18.345 ? 202  LYS B CG  1 
ATOM   5675 C  CD  . LYS B 1 210 ? -17.491 -8.144  -2.039  1   16.557 ? 202  LYS B CD  1 
ATOM   5676 C  CE  . LYS B 1 210 ? -18.445 -9.083  -1.339  1   16.461 ? 202  LYS B CE  1 
ATOM   5677 N  NZ  . LYS B 1 210 ? -17.828 -10.015 -0.37   1   17.233 ? 202  LYS B NZ  1 
ATOM   5678 N  N   . GLN B 1 211 ? -15.042 -3.751  -3.351  1   17.866 ? 203  GLN B N   1 
ATOM   5679 C  CA  . GLN B 1 211 ? -14.382 -2.644  -4.052  1   17.932 ? 203  GLN B CA  1 
ATOM   5680 C  C   . GLN B 1 211 ? -13.977 -3.092  -5.449  1   17.92  ? 203  GLN B C   1 
ATOM   5681 O  O   . GLN B 1 211 ? -13.027 -3.85   -5.607  1   18.807 ? 203  GLN B O   1 
ATOM   5682 C  CB  . GLN B 1 211 ? -13.208 -2.121  -3.224  1   17.135 ? 203  GLN B CB  1 
ATOM   5683 C  CG  . GLN B 1 211 ? -13.71  -1.314  -2.027  1   17.549 ? 203  GLN B CG  1 
ATOM   5684 C  CD  . GLN B 1 211 ? -12.576 -0.747  -1.187  1   17.189 ? 203  GLN B CD  1 
ATOM   5685 O  OE1 . GLN B 1 211 ? -11.762 -1.523  -0.645  1   19.335 ? 203  GLN B OE1 1 
ATOM   5686 N  NE2 . GLN B 1 211 ? -12.532 0.574   -1.068  1   18.086 ? 203  GLN B NE2 1 
ATOM   5687 N  N   . CYS B 1 212 ? -14.754 -2.611  -6.444  1   18.801 ? 204  CYS B N   1 
ATOM   5688 C  CA  . CYS B 1 212 ? -14.565 -2.964  -7.851  1   19.709 ? 204  CYS B CA  1 
ATOM   5689 C  C   . CYS B 1 212 ? -13.144 -2.59   -8.313  1   19.238 ? 204  CYS B C   1 
ATOM   5690 O  O   . CYS B 1 212 ? -12.773 -1.429  -8.235  1   19.898 ? 204  CYS B O   1 
ATOM   5691 C  CB  . CYS B 1 212 ? -15.616 -2.188  -8.64   1   17.965 ? 204  CYS B CB  1 
ATOM   5692 S  SG  . CYS B 1 212 ? -15.559 -2.529  -10.43  1   21.175 ? 204  CYS B SG  1 
ATOM   5693 N  N   . SER B 1 213 ? -12.414 -3.58   -8.841  1   20.61  ? 205  SER B N   1 
ATOM   5694 C  CA  . SER B 1 213 ? -11.077 -3.355  -9.367  1   21.046 ? 205  SER B CA  1 
ATOM   5695 C  C   . SER B 1 213 ? -11.093 -2.544  -10.667 1   21.77  ? 205  SER B C   1 
ATOM   5696 O  O   . SER B 1 213 ? -10.032 -2.03   -11.02  1   25.823 ? 205  SER B O   1 
ATOM   5697 C  CB  . SER B 1 213 ? -10.314 -4.654  -9.535  1   21.543 ? 205  SER B CB  1 
ATOM   5698 O  OG  . SER B 1 213 ? -10.933 -5.443  -10.559 1   25.521 ? 205  SER B OG  1 
ATOM   5699 N  N   . VAL B 1 214 ? -12.253 -2.439  -11.34  1   20.27  ? 206  VAL B N   1 
ATOM   5700 C  CA  . VAL B 1 214 ? -12.303 -1.755  -12.625 1   24.033 ? 206  VAL B CA  1 
ATOM   5701 C  C   . VAL B 1 214 ? -12.634 -0.279  -12.396 1   25.422 ? 206  VAL B C   1 
ATOM   5702 O  O   . VAL B 1 214 ? -11.889 0.604   -12.881 1   26.272 ? 206  VAL B O   1 
ATOM   5703 C  CB  . VAL B 1 214 ? -13.303 -2.447  -13.565 1   24.709 ? 206  VAL B CB  1 
ATOM   5704 C  CG1 . VAL B 1 214 ? -13.52  -1.652  -14.865 1   26.401 ? 206  VAL B CG1 1 
ATOM   5705 C  CG2 . VAL B 1 214 ? -12.859 -3.876  -13.886 1   27.047 ? 206  VAL B CG2 1 
ATOM   5706 N  N   . THR B 1 215 ? -13.744 -0.025  -11.682 1   21.693 ? 207  THR B N   1 
ATOM   5707 C  CA  . THR B 1 215 ? -14.249 1.32    -11.463 1   21.004 ? 207  THR B CA  1 
ATOM   5708 C  C   . THR B 1 215 ? -13.648 1.978   -10.218 1   21.258 ? 207  THR B C   1 
ATOM   5709 O  O   . THR B 1 215 ? -13.766 3.19    -10.063 1   23.482 ? 207  THR B O   1 
ATOM   5710 C  CB  . THR B 1 215 ? -15.779 1.362   -11.385 1   22.726 ? 207  THR B CB  1 
ATOM   5711 O  OG1 . THR B 1 215 ? -16.145 0.592   -10.225 1   20.163 ? 207  THR B OG1 1 
ATOM   5712 C  CG2 . THR B 1 215 ? -16.452 0.787   -12.624 1   21.821 ? 207  THR B CG2 1 
ATOM   5713 N  N   . GLY B 1 216 ? -13.211 1.156   -9.232  1   20.123 ? 208  GLY B N   1 
ATOM   5714 C  CA  . GLY B 1 216 ? -12.888 1.695   -7.913  1   19.185 ? 208  GLY B CA  1 
ATOM   5715 C  C   . GLY B 1 216 ? -14.139 1.912   -7.055  1   20.006 ? 208  GLY B C   1 
ATOM   5716 O  O   . GLY B 1 216 ? -14.023 2.412   -5.941  1   22.31  ? 208  GLY B O   1 
ATOM   5717 N  N   . ASN B 1 217 ? -15.34  1.596   -7.568  1   20.093 ? 209  ASN B N   1 
ATOM   5718 C  CA  . ASN B 1 217 ? -16.546 1.842   -6.778  1   17.696 ? 209  ASN B CA  1 
ATOM   5719 C  C   . ASN B 1 217 ? -16.609 0.89    -5.574  1   17.813 ? 209  ASN B C   1 
ATOM   5720 O  O   . ASN B 1 217 ? -16.258 -0.282  -5.688  1   19.414 ? 209  ASN B O   1 
ATOM   5721 C  CB  . ASN B 1 217 ? -17.803 1.664   -7.618  1   18.741 ? 209  ASN B CB  1 
ATOM   5722 C  CG  . ASN B 1 217 ? -17.959 2.712   -8.72   1   20.677 ? 209  ASN B CG  1 
ATOM   5723 O  OD1 . ASN B 1 217 ? -17.232 3.712   -8.788  1   20.213 ? 209  ASN B OD1 1 
ATOM   5724 N  ND2 . ASN B 1 217 ? -18.963 2.513   -9.556  1   20.282 ? 209  ASN B ND2 1 
ATOM   5725 N  N   . LEU B 1 218 ? -17.154 1.395   -4.464  1   17.427 ? 210  LEU B N   1 
ATOM   5726 C  CA  . LEU B 1 218 ? -17.655 0.562   -3.375  1   18.06  ? 210  LEU B CA  1 
ATOM   5727 C  C   . LEU B 1 218 ? -19.064 0.12    -3.776  1   16.263 ? 210  LEU B C   1 
ATOM   5728 O  O   . LEU B 1 218 ? -19.979 0.939   -3.752  1   16.992 ? 210  LEU B O   1 
ATOM   5729 C  CB  . LEU B 1 218 ? -17.626 1.353   -2.058  1   18.256 ? 210  LEU B CB  1 
ATOM   5730 C  CG  . LEU B 1 218 ? -18.045 0.561   -0.797  1   16.639 ? 210  LEU B CG  1 
ATOM   5731 C  CD1 . LEU B 1 218 ? -16.932 -0.349  -0.364  1   17.269 ? 210  LEU B CD1 1 
ATOM   5732 C  CD2 . LEU B 1 218 ? -18.367 1.521   0.341   1   18.451 ? 210  LEU B CD2 1 
ATOM   5733 N  N   . VAL B 1 219 ? -19.211 -1.177  -4.037  1   16.882 ? 211  VAL B N   1 
ATOM   5734 C  CA  . VAL B 1 219 ? -20.484 -1.683  -4.539  1   15.134 ? 211  VAL B CA  1 
ATOM   5735 C  C   . VAL B 1 219 ? -21.13  -2.469  -3.398  1   17.058 ? 211  VAL B C   1 
ATOM   5736 O  O   . VAL B 1 219 ? -20.483 -3.361  -2.827  1   18.224 ? 211  VAL B O   1 
ATOM   5737 C  CB  . VAL B 1 219 ? -20.237 -2.576  -5.762  1   16.868 ? 211  VAL B CB  1 
ATOM   5738 C  CG1 . VAL B 1 219 ? -21.587 -3.038  -6.308  1   19.712 ? 211  VAL B CG1 1 
ATOM   5739 C  CG2 . VAL B 1 219 ? -19.481 -1.844  -6.905  1   19.024 ? 211  VAL B CG2 1 
ATOM   5740 N  N   . GLY B 1 220 ? -22.383 -2.122  -3.085  1   16.289 ? 212  GLY B N   1 
ATOM   5741 C  CA  . GLY B 1 220 ? -23.054 -2.857  -2.018  1   16.964 ? 212  GLY B CA  1 
ATOM   5742 C  C   . GLY B 1 220 ? -24.546 -2.617  -1.993  1   19.485 ? 212  GLY B C   1 
ATOM   5743 O  O   . GLY B 1 220 ? -25.176 -2.218  -2.981  1   17.34  ? 212  GLY B O   1 
ATOM   5744 N  N   . PHE B 1 221 ? -25.127 -2.911  -0.827  1   16.521 ? 213  PHE B N   1 
ATOM   5745 C  CA  . PHE B 1 221 ? -26.562 -2.863  -0.654  1   17.309 ? 213  PHE B CA  1 
ATOM   5746 C  C   . PHE B 1 221 ? -26.798 -2.696  0.839   1   17.274 ? 213  PHE B C   1 
ATOM   5747 O  O   . PHE B 1 221 ? -25.864 -2.857  1.623   1   17.696 ? 213  PHE B O   1 
ATOM   5748 C  CB  . PHE B 1 221 ? -27.256 -4.148  -1.162  1   17.574 ? 213  PHE B CB  1 
ATOM   5749 C  CG  . PHE B 1 221 ? -26.794 -5.379  -0.403  1   16.815 ? 213  PHE B CG  1 
ATOM   5750 C  CD1 . PHE B 1 221 ? -25.524 -5.936  -0.625  1   14.331 ? 213  PHE B CD1 1 
ATOM   5751 C  CD2 . PHE B 1 221 ? -27.619 -5.93   0.595   1   18.97  ? 213  PHE B CD2 1 
ATOM   5752 C  CE1 . PHE B 1 221 ? -25.098 -7.07   0.079   1   14.608 ? 213  PHE B CE1 1 
ATOM   5753 C  CE2 . PHE B 1 221 ? -27.167 -7.036  1.357   1   18.017 ? 213  PHE B CE2 1 
ATOM   5754 C  CZ  . PHE B 1 221 ? -25.929 -7.617  1.072   1   15.726 ? 213  PHE B CZ  1 
ATOM   5755 N  N   . GLY B 1 222 ? -28.026 -2.334  1.206   1   18.555 ? 214  GLY B N   1 
ATOM   5756 C  CA  . GLY B 1 222 ? -28.481 -2.457  2.592   1   18.478 ? 214  GLY B CA  1 
ATOM   5757 C  C   . GLY B 1 222 ? -29.844 -3.141  2.563   1   17.323 ? 214  GLY B C   1 
ATOM   5758 O  O   . GLY B 1 222 ? -30.684 -2.781  1.726   1   18.736 ? 214  GLY B O   1 
ATOM   5759 N  N   . TYR B 1 223 ? -30.065 -4.158  3.408   1   16.114 ? 215  TYR B N   1 
ATOM   5760 C  CA  . TYR B 1 223 ? -31.378 -4.794  3.499   1   15.831 ? 215  TYR B CA  1 
ATOM   5761 C  C   . TYR B 1 223 ? -32.04  -4.41   4.819   1   17.663 ? 215  TYR B C   1 
ATOM   5762 O  O   . TYR B 1 223 ? -31.437 -3.752  5.68    1   17.856 ? 215  TYR B O   1 
ATOM   5763 C  CB  . TYR B 1 223 ? -31.342 -6.312  3.25    1   17.308 ? 215  TYR B CB  1 
ATOM   5764 C  CG  . TYR B 1 223 ? -30.712 -7.102  4.389   1   16.225 ? 215  TYR B CG  1 
ATOM   5765 C  CD1 . TYR B 1 223 ? -29.321 -7.231  4.528   1   18.133 ? 215  TYR B CD1 1 
ATOM   5766 C  CD2 . TYR B 1 223 ? -31.538 -7.726  5.316   1   17.071 ? 215  TYR B CD2 1 
ATOM   5767 C  CE1 . TYR B 1 223 ? -28.766 -7.95   5.596   1   17.11  ? 215  TYR B CE1 1 
ATOM   5768 C  CE2 . TYR B 1 223 ? -31.003 -8.419  6.395   1   16.014 ? 215  TYR B CE2 1 
ATOM   5769 C  CZ  . TYR B 1 223 ? -29.626 -8.534  6.525   1   16.112 ? 215  TYR B CZ  1 
ATOM   5770 O  OH  . TYR B 1 223 ? -29.089 -9.279  7.574   1   16.239 ? 215  TYR B OH  1 
ATOM   5771 N  N   . GLU B 1 224 ? -33.339 -4.755  4.96    1   16.258 ? 216  GLU B N   1 
ATOM   5772 C  CA  . GLU B 1 224 ? -34.175 -4.108  5.974   1   16.498 ? 216  GLU B CA  1 
ATOM   5773 C  C   . GLU B 1 224 ? -33.978 -2.6    5.904   1   17.715 ? 216  GLU B C   1 
ATOM   5774 O  O   . GLU B 1 224 ? -33.836 -1.903  6.902   1   17.476 ? 216  GLU B O   1 
ATOM   5775 C  CB  . GLU B 1 224 ? -34     -4.666  7.404   1   15.768 ? 216  GLU B CB  1 
ATOM   5776 C  CG  . GLU B 1 224 ? -34.223 -6.169  7.437   1   16.856 ? 216  GLU B CG  1 
ATOM   5777 C  CD  . GLU B 1 224 ? -34.445 -6.791  8.821   1   15.573 ? 216  GLU B CD  1 
ATOM   5778 O  OE1 . GLU B 1 224 ? -34.789 -6.051  9.777   1   16.481 ? 216  GLU B OE1 1 
ATOM   5779 O  OE2 . GLU B 1 224 ? -34.295 -8.013  8.889   1   19.803 ? 216  GLU B OE2 1 
ATOM   5780 N  N   . ALA B 1 225 ? -33.939 -2.077  4.658   1   17.406 ? 217  ALA B N   1 
ATOM   5781 C  CA  . ALA B 1 225 ? -33.402 -0.742  4.447   1   17.26  ? 217  ALA B CA  1 
ATOM   5782 C  C   . ALA B 1 225 ? -34.309 0.365   4.978   1   18.973 ? 217  ALA B C   1 
ATOM   5783 O  O   . ALA B 1 225 ? -33.843 1.486   5.147   1   18.252 ? 217  ALA B O   1 
ATOM   5784 C  CB  . ALA B 1 225 ? -33.118 -0.517  2.973   1   19.631 ? 217  ALA B CB  1 
ATOM   5785 N  N   . LYS B 1 226 ? -35.605 0.035   5.247   1   19.333 ? 218  LYS B N   1 
ATOM   5786 C  CA  . LYS B 1 226 ? -36.561 1.004   5.757   1   20.373 ? 218  LYS B CA  1 
ATOM   5787 C  C   . LYS B 1 226 ? -36.962 0.74    7.201   1   24.945 ? 218  LYS B C   1 
ATOM   5788 O  O   . LYS B 1 226 ? -37.888 1.39    7.705   1   25.811 ? 218  LYS B O   1 
ATOM   5789 C  CB  . LYS B 1 226 ? -37.791 1.102   4.838   1   20.037 ? 218  LYS B CB  1 
ATOM   5790 C  CG  . LYS B 1 226 ? -37.383 1.643   3.458   1   21.95  ? 218  LYS B CG  1 
ATOM   5791 C  CD  . LYS B 1 226 ? -38.655 2.015   2.686   1   28.46  ? 218  LYS B CD  1 
ATOM   5792 C  CE  . LYS B 1 226 ? -38.234 2.434   1.306   1   28.231 ? 218  LYS B CE  1 
ATOM   5793 N  NZ  . LYS B 1 226 ? -39.474 2.824   0.615   1   35.037 ? 218  LYS B NZ  1 
ATOM   5794 N  N   . GLY B 1 227 ? -36.222 -0.151  7.874   1   19.081 ? 219  GLY B N   1 
ATOM   5795 C  CA  . GLY B 1 227 ? -36.515 -0.425  9.281   1   19.605 ? 219  GLY B CA  1 
ATOM   5796 C  C   . GLY B 1 227 ? -36.714 -1.899  9.563   1   17.286 ? 219  GLY B C   1 
ATOM   5797 O  O   . GLY B 1 227 ? -36.636 -2.778  8.694   1   18.019 ? 219  GLY B O   1 
ATOM   5798 N  N   . LEU B 1 228 ? -36.983 -2.18   10.849  1   17.594 ? 220  LEU B N   1 
ATOM   5799 C  CA  . LEU B 1 228 ? -37.054 -3.568  11.28   1   18.012 ? 220  LEU B CA  1 
ATOM   5800 C  C   . LEU B 1 228 ? -38.051 -4.413  10.473  1   19.385 ? 220  LEU B C   1 
ATOM   5801 O  O   . LEU B 1 228 ? -39.226 -4.046  10.36   1   19.79  ? 220  LEU B O   1 
ATOM   5802 C  CB  . LEU B 1 228 ? -37.506 -3.456  12.742  1   23.044 ? 220  LEU B CB  1 
ATOM   5803 C  CG  . LEU B 1 228 ? -37.162 -4.642  13.63   1   23.148 ? 220  LEU B CG  1 
ATOM   5804 C  CD1 . LEU B 1 228 ? -35.643 -4.724  13.91   1   20.757 ? 220  LEU B CD1 1 
ATOM   5805 C  CD2 . LEU B 1 228 ? -37.913 -4.417  14.942  1   22.523 ? 220  LEU B CD2 1 
ATOM   5806 N  N   . ALA B 1 229 ? -37.586 -5.562  9.98    1   17.774 ? 221  ALA B N   1 
ATOM   5807 C  CA  . ALA B 1 229 ? -38.343 -6.59   9.274   1   19.351 ? 221  ALA B CA  1 
ATOM   5808 C  C   . ALA B 1 229 ? -38.872 -6.114  7.905   1   22.02  ? 221  ALA B C   1 
ATOM   5809 O  O   . ALA B 1 229 ? -39.624 -6.86   7.26    1   25.137 ? 221  ALA B O   1 
ATOM   5810 C  CB  . ALA B 1 229 ? -39.479 -7.173  10.159  1   21.25  ? 221  ALA B CB  1 
ATOM   5811 N  N   . THR B 1 230 ? -38.401 -4.955  7.421   1   18.596 ? 222  THR B N   1 
ATOM   5812 C  CA  . THR B 1 230 ? -38.775 -4.477  6.079   1   18.176 ? 222  THR B CA  1 
ATOM   5813 C  C   . THR B 1 230 ? -38.072 -5.298  4.994   1   19.416 ? 222  THR B C   1 
ATOM   5814 O  O   . THR B 1 230 ? -36.922 -5.754  5.13    1   19.383 ? 222  THR B O   1 
ATOM   5815 C  CB  . THR B 1 230 ? -38.571 -2.966  5.898   1   19.184 ? 222  THR B CB  1 
ATOM   5816 O  OG1 . THR B 1 230 ? -37.187 -2.618  6.017   1   18.407 ? 222  THR B OG1 1 
ATOM   5817 C  CG2 . THR B 1 230 ? -39.416 -2.137  6.85    1   18.055 ? 222  THR B CG2 1 
ATOM   5818 N  N   . LYS B 1 231 ? -38.774 -5.504  3.86    1   19.479 ? 223  LYS B N   1 
ATOM   5819 C  CA  . LYS B 1 231 ? -38.225 -6.281  2.757   1   19.179 ? 223  LYS B CA  1 
ATOM   5820 C  C   . LYS B 1 231 ? -37.381 -5.434  1.798   1   17.649 ? 223  LYS B C   1 
ATOM   5821 O  O   . LYS B 1 231 ? -36.707 -5.987  0.916   1   18.943 ? 223  LYS B O   1 
ATOM   5822 C  CB  . LYS B 1 231 ? -39.396 -6.891  1.962   1   21.946 ? 223  LYS B CB  1 
ATOM   5823 C  CG  . LYS B 1 231 ? -40.002 -8.118  2.68    1   25.688 ? 223  LYS B CG  1 
ATOM   5824 C  CD  . LYS B 1 231 ? -41.047 -8.844  1.835   1   29.149 ? 223  LYS B CD  1 
ATOM   5825 C  CE  . LYS B 1 231 ? -42.3   -8.04   1.721   1   32.901 ? 223  LYS B CE  1 
ATOM   5826 N  NZ  . LYS B 1 231 ? -43.206 -8.725  0.799   1   47.733 ? 223  LYS B NZ  1 
ATOM   5827 N  N   . ASP B 1 232 ? -37.389 -4.122  2.021   1   16.704 ? 224  ASP B N   1 
ATOM   5828 C  CA  . ASP B 1 232 ? -36.671 -3.176  1.168   1   17.7   ? 224  ASP B CA  1 
ATOM   5829 C  C   . ASP B 1 232 ? -35.17  -3.464  1.141   1   21.081 ? 224  ASP B C   1 
ATOM   5830 O  O   . ASP B 1 232 ? -34.522 -3.702  2.18    1   19.692 ? 224  ASP B O   1 
ATOM   5831 C  CB  . ASP B 1 232 ? -36.913 -1.759  1.626   1   17.914 ? 224  ASP B CB  1 
ATOM   5832 C  CG  . ASP B 1 232 ? -38.398 -1.455  1.668   1   21.227 ? 224  ASP B CG  1 
ATOM   5833 O  OD1 . ASP B 1 232 ? -38.946 -1.08   0.599   1   22.748 ? 224  ASP B OD1 1 
ATOM   5834 O  OD2 . ASP B 1 232 ? -39.017 -1.638  2.718   1   21.472 ? 224  ASP B OD2 1 
ATOM   5835 N  N   . VAL B 1 233 ? -34.624 -3.379  -0.068  1   17.997 ? 225  VAL B N   1 
ATOM   5836 C  CA  . VAL B 1 233 ? -33.184 -3.47   -0.321  1   17.616 ? 225  VAL B CA  1 
ATOM   5837 C  C   . VAL B 1 233 ? -32.778 -2.234  -1.106  1   19.182 ? 225  VAL B C   1 
ATOM   5838 O  O   . VAL B 1 233 ? -33.423 -1.906  -2.109  1   18.822 ? 225  VAL B O   1 
ATOM   5839 C  CB  . VAL B 1 233 ? -32.824 -4.771  -1.054  1   17.722 ? 225  VAL B CB  1 
ATOM   5840 C  CG1 . VAL B 1 233 ? -31.369 -4.812  -1.486  1   20.683 ? 225  VAL B CG1 1 
ATOM   5841 C  CG2 . VAL B 1 233 ? -33.174 -6.003  -0.22   1   17.857 ? 225  VAL B CG2 1 
ATOM   5842 N  N   . TYR B 1 234 ? -31.773 -1.51   -0.627  1   19.523 ? 226  TYR B N   1 
ATOM   5843 C  CA  . TYR B 1 234 ? -31.167 -0.417  -1.37   1   17.709 ? 226  TYR B CA  1 
ATOM   5844 C  C   . TYR B 1 234 ? -29.828 -0.845  -1.97   1   19.16  ? 226  TYR B C   1 
ATOM   5845 O  O   . TYR B 1 234 ? -28.956 -1.282  -1.222  1   20.267 ? 226  TYR B O   1 
ATOM   5846 C  CB  . TYR B 1 234 ? -30.994 0.726   -0.368  1   18.983 ? 226  TYR B CB  1 
ATOM   5847 C  CG  . TYR B 1 234 ? -30.307 1.96    -0.941  1   20.09  ? 226  TYR B CG  1 
ATOM   5848 C  CD1 . TYR B 1 234 ? -30.906 2.723   -1.955  1   19.883 ? 226  TYR B CD1 1 
ATOM   5849 C  CD2 . TYR B 1 234 ? -29.043 2.346   -0.498  1   20.346 ? 226  TYR B CD2 1 
ATOM   5850 C  CE1 . TYR B 1 234 ? -30.285 3.855   -2.477  1   20.953 ? 226  TYR B CE1 1 
ATOM   5851 C  CE2 . TYR B 1 234 ? -28.394 3.462   -1.022  1   20.192 ? 226  TYR B CE2 1 
ATOM   5852 C  CZ  . TYR B 1 234 ? -29.027 4.222   -2.003  1   20.144 ? 226  TYR B CZ  1 
ATOM   5853 O  OH  . TYR B 1 234 ? -28.411 5.317   -2.533  1   20.476 ? 226  TYR B OH  1 
ATOM   5854 N  N   . TYR B 1 235 ? -29.644 -0.762  -3.303  1   17.471 ? 227  TYR B N   1 
ATOM   5855 C  CA  . TYR B 1 235 ? -28.405 -1.071  -3.988  1   17.669 ? 227  TYR B CA  1 
ATOM   5856 C  C   . TYR B 1 235 ? -27.685 0.248   -4.269  1   17.994 ? 227  TYR B C   1 
ATOM   5857 O  O   . TYR B 1 235 ? -28.34  1.266   -4.54   1   18.279 ? 227  TYR B O   1 
ATOM   5858 C  CB  . TYR B 1 235 ? -28.719 -1.798  -5.316  1   19.059 ? 227  TYR B CB  1 
ATOM   5859 C  CG  . TYR B 1 235 ? -27.721 -1.557  -6.449  1   18.31  ? 227  TYR B CG  1 
ATOM   5860 C  CD1 . TYR B 1 235 ? -26.458 -2.165  -6.471  1   19.565 ? 227  TYR B CD1 1 
ATOM   5861 C  CD2 . TYR B 1 235 ? -28.069 -0.731  -7.521  1   18.991 ? 227  TYR B CD2 1 
ATOM   5862 C  CE1 . TYR B 1 235 ? -25.554 -1.95   -7.513  1   19.632 ? 227  TYR B CE1 1 
ATOM   5863 C  CE2 . TYR B 1 235 ? -27.179 -0.514  -8.566  1   18.828 ? 227  TYR B CE2 1 
ATOM   5864 C  CZ  . TYR B 1 235 ? -25.94  -1.135  -8.58   1   19.295 ? 227  TYR B CZ  1 
ATOM   5865 O  OH  . TYR B 1 235 ? -25.044 -0.864  -9.595  1   19.15  ? 227  TYR B OH  1 
ATOM   5866 N  N   . PHE B 1 236 ? -26.344 0.244   -4.15   1   17.931 ? 228  PHE B N   1 
ATOM   5867 C  CA  . PHE B 1 236 ? -25.585 1.451   -4.416  1   17.457 ? 228  PHE B CA  1 
ATOM   5868 C  C   . PHE B 1 236 ? -24.193 1.11    -4.938  1   17.946 ? 228  PHE B C   1 
ATOM   5869 O  O   . PHE B 1 236 ? -23.632 0.024   -4.718  1   19.047 ? 228  PHE B O   1 
ATOM   5870 C  CB  . PHE B 1 236 ? -25.432 2.361   -3.179  1   16.873 ? 228  PHE B CB  1 
ATOM   5871 C  CG  . PHE B 1 236 ? -24.713 1.635   -2.042  1   17.857 ? 228  PHE B CG  1 
ATOM   5872 C  CD1 . PHE B 1 236 ? -23.31  1.632   -2.007  1   19.694 ? 228  PHE B CD1 1 
ATOM   5873 C  CD2 . PHE B 1 236 ? -25.431 0.958   -1.042  1   16.952 ? 228  PHE B CD2 1 
ATOM   5874 C  CE1 . PHE B 1 236 ? -22.598 0.927   -1.021  1   19.164 ? 228  PHE B CE1 1 
ATOM   5875 C  CE2 . PHE B 1 236 ? -24.715 0.282   -0.038  1   17.584 ? 228  PHE B CE2 1 
ATOM   5876 C  CZ  . PHE B 1 236 ? -23.323 0.274   -0.03   1   18.497 ? 228  PHE B CZ  1 
ATOM   5877 N  N   . GLU B 1 237 ? -23.616 2.103   -5.636  1   17.987 ? 229  GLU B N   1 
ATOM   5878 C  CA  . GLU B 1 237 ? -22.18  2.122   -5.916  1   17.708 ? 229  GLU B CA  1 
ATOM   5879 C  C   . GLU B 1 237 ? -21.703 3.519   -5.575  1   20.11  ? 229  GLU B C   1 
ATOM   5880 O  O   . GLU B 1 237 ? -22.25  4.498   -6.086  1   18.684 ? 229  GLU B O   1 
ATOM   5881 C  CB  . GLU B 1 237 ? -21.853 1.831   -7.379  1   19.132 ? 229  GLU B CB  1 
ATOM   5882 C  CG  . GLU B 1 237 ? -22.45  0.505   -7.87   1   19.427 ? 229  GLU B CG  1 
ATOM   5883 C  CD  . GLU B 1 237 ? -21.83  -0.178  -9.079  1   19.591 ? 229  GLU B CD  1 
ATOM   5884 O  OE1 . GLU B 1 237 ? -20.723 0.209   -9.523  1   18.967 ? 229  GLU B OE1 1 
ATOM   5885 O  OE2 . GLU B 1 237 ? -22.468 -1.153  -9.556  1   19.406 ? 229  GLU B OE2 1 
ATOM   5886 N  N   . VAL B 1 238 ? -20.739 3.606   -4.642  1   18.495 ? 230  VAL B N   1 
ATOM   5887 C  CA  . VAL B 1 238 ? -20.088 4.827   -4.205  1   18.924 ? 230  VAL B CA  1 
ATOM   5888 C  C   . VAL B 1 238 ? -18.753 4.923   -4.945  1   18.044 ? 230  VAL B C   1 
ATOM   5889 O  O   . VAL B 1 238 ? -17.901 4.029   -4.884  1   18.296 ? 230  VAL B O   1 
ATOM   5890 C  CB  . VAL B 1 238 ? -19.846 4.835   -2.68   1   20.443 ? 230  VAL B CB  1 
ATOM   5891 C  CG1 . VAL B 1 238 ? -19.11  6.114   -2.283  1   19.294 ? 230  VAL B CG1 1 
ATOM   5892 C  CG2 . VAL B 1 238 ? -21.136 4.704   -1.872  1   22.236 ? 230  VAL B CG2 1 
ATOM   5893 N  N   . ASP B 1 239 ? -18.549 6.045   -5.662  1   20.225 ? 231  ASP B N   1 
ATOM   5894 C  CA  . ASP B 1 239 ? -17.34  6.137   -6.459  1   20.915 ? 231  ASP B CA  1 
ATOM   5895 C  C   . ASP B 1 239 ? -16.109 6.457   -5.589  1   21.451 ? 231  ASP B C   1 
ATOM   5896 O  O   . ASP B 1 239 ? -16.239 6.679   -4.364  1   20.877 ? 231  ASP B O   1 
ATOM   5897 C  CB  . ASP B 1 239 ? -17.581 7.112   -7.612  1   22.238 ? 231  ASP B CB  1 
ATOM   5898 C  CG  . ASP B 1 239 ? -17.519 8.596   -7.271  1   22.814 ? 231  ASP B CG  1 
ATOM   5899 O  OD1 . ASP B 1 239 ? -17.221 8.997   -6.127  1   24.121 ? 231  ASP B OD1 1 
ATOM   5900 O  OD2 . ASP B 1 239 ? -17.788 9.396   -8.199  1   24.486 ? 231  ASP B OD2 1 
ATOM   5901 N  N   . PRO B 1 240 ? -14.884 6.495   -6.165  1   19.997 ? 232  PRO B N   1 
ATOM   5902 C  CA  . PRO B 1 240 ? -13.663 6.757   -5.379  1   21.603 ? 232  PRO B CA  1 
ATOM   5903 C  C   . PRO B 1 240 ? -13.616 8.108   -4.696  1   21.078 ? 232  PRO B C   1 
ATOM   5904 O  O   . PRO B 1 240 ? -12.773 8.303   -3.79   1   21.974 ? 232  PRO B O   1 
ATOM   5905 C  CB  . PRO B 1 240 ? -12.559 6.658   -6.456  1   23.096 ? 232  PRO B CB  1 
ATOM   5906 C  CG  . PRO B 1 240 ? -13.093 5.626   -7.443  1   24.348 ? 232  PRO B CG  1 
ATOM   5907 C  CD  . PRO B 1 240 ? -14.553 6.028   -7.548  1   22.129 ? 232  PRO B CD  1 
ATOM   5908 N  N   . SER B 1 241 ? -14.516 9.016   -5.106  1   22.059 ? 233  SER B N   1 
ATOM   5909 C  CA  . SER B 1 241 ? -14.584 10.318  -4.468  1   22.975 ? 233  SER B CA  1 
ATOM   5910 C  C   . SER B 1 241 ? -15.597 10.384  -3.325  1   23.998 ? 233  SER B C   1 
ATOM   5911 O  O   . SER B 1 241 ? -15.716 11.415  -2.666  1   27.151 ? 233  SER B O   1 
ATOM   5912 C  CB  . SER B 1 241 ? -14.807 11.44   -5.493  1   29.886 ? 233  SER B CB  1 
ATOM   5913 O  OG  . SER B 1 241 ? -16.18  11.468  -5.864  1   33.415 ? 233  SER B OG  1 
ATOM   5914 N  N   . GLY B 1 242 ? -16.352 9.294   -3.103  1   24.374 ? 234  GLY B N   1 
ATOM   5915 C  CA  . GLY B 1 242 ? -17.319 9.241   -2.02   1   20.898 ? 234  GLY B CA  1 
ATOM   5916 C  C   . GLY B 1 242 ? -18.753 9.55    -2.447  1   22.469 ? 234  GLY B C   1 
ATOM   5917 O  O   . GLY B 1 242 ? -19.582 9.773   -1.566  1   22.746 ? 234  GLY B O   1 
ATOM   5918 N  N   . LYS B 1 243 ? -19.04  9.631   -3.766  1   23.084 ? 235  LYS B N   1 
ATOM   5919 C  CA  . LYS B 1 243 ? -20.374 10.025  -4.227  1   23.971 ? 235  LYS B CA  1 
ATOM   5920 C  C   . LYS B 1 243 ? -21.139 8.783   -4.691  1   20.705 ? 235  LYS B C   1 
ATOM   5921 O  O   . LYS B 1 243 ? -20.566 7.942   -5.392  1   20.363 ? 235  LYS B O   1 
ATOM   5922 C  CB  . LYS B 1 243 ? -20.149 11.009  -5.4    1   24.176 ? 235  LYS B CB  1 
ATOM   5923 C  CG  . LYS B 1 243 ? -21.424 11.509  -6.047  1   34.183 ? 235  LYS B CG  1 
ATOM   5924 C  CD  . LYS B 1 243 ? -21.231 12.314  -7.335  1   37.553 ? 235  LYS B CD  1 
ATOM   5925 C  CE  . LYS B 1 243 ? -22.549 12.501  -8.037  1   49.165 ? 235  LYS B CE  1 
ATOM   5926 N  NZ  . LYS B 1 243 ? -23.477 13.318  -7.241  1   56.942 ? 235  LYS B NZ  1 
ATOM   5927 N  N   . VAL B 1 244 ? -22.45  8.71    -4.366  1   21.733 ? 236  VAL B N   1 
ATOM   5928 C  CA  . VAL B 1 244 ? -23.29  7.633   -4.882  1   20.438 ? 236  VAL B CA  1 
ATOM   5929 C  C   . VAL B 1 244 ? -23.548 7.922   -6.364  1   21.422 ? 236  VAL B C   1 
ATOM   5930 O  O   . VAL B 1 244 ? -24.163 8.939   -6.661  1   25.369 ? 236  VAL B O   1 
ATOM   5931 C  CB  . VAL B 1 244 ? -24.598 7.427   -4.101  1   20.693 ? 236  VAL B CB  1 
ATOM   5932 C  CG1 . VAL B 1 244 ? -25.559 6.435   -4.771  1   20.336 ? 236  VAL B CG1 1 
ATOM   5933 C  CG2 . VAL B 1 244 ? -24.311 6.996   -2.674  1   20.88  ? 236  VAL B CG2 1 
ATOM   5934 N  N   . VAL B 1 245 ? -23.03  7.042   -7.235  1   21.055 ? 237  VAL B N   1 
ATOM   5935 C  CA  . VAL B 1 245 ? -23.145 7.261   -8.673  1   21.66  ? 237  VAL B CA  1 
ATOM   5936 C  C   . VAL B 1 245 ? -24.164 6.333   -9.319  1   23.935 ? 237  VAL B C   1 
ATOM   5937 O  O   . VAL B 1 245 ? -24.558 6.573   -10.471 1   23.68  ? 237  VAL B O   1 
ATOM   5938 C  CB  . VAL B 1 245 ? -21.787 7.202   -9.404  1   21.71  ? 237  VAL B CB  1 
ATOM   5939 C  CG1 . VAL B 1 245 ? -20.895 8.374   -9.006  1   22.802 ? 237  VAL B CG1 1 
ATOM   5940 C  CG2 . VAL B 1 245 ? -21.063 5.858   -9.245  1   21.312 ? 237  VAL B CG2 1 
ATOM   5941 N  N   . ARG B 1 246 ? -24.57  5.251   -8.633  1   21.83  ? 238  ARG B N   1 
ATOM   5942 C  CA  . ARG B 1 246 ? -25.595 4.333   -9.083  1   19.447 ? 238  ARG B CA  1 
ATOM   5943 C  C   . ARG B 1 246 ? -26.343 3.833   -7.852  1   21.621 ? 238  ARG B C   1 
ATOM   5944 O  O   . ARG B 1 246 ? -25.739 3.576   -6.809  1   21.739 ? 238  ARG B O   1 
ATOM   5945 C  CB  . ARG B 1 246 ? -25.021 3.058   -9.705  1   21.855 ? 238  ARG B CB  1 
ATOM   5946 C  CG  . ARG B 1 246 ? -24.302 3.26    -11.033 1   23.091 ? 238  ARG B CG  1 
ATOM   5947 C  CD  . ARG B 1 246 ? -23.489 2.029   -11.322 1   25.447 ? 238  ARG B CD  1 
ATOM   5948 N  NE  . ARG B 1 246 ? -23.12  1.902   -12.735 1   28.871 ? 238  ARG B NE  1 
ATOM   5949 C  CZ  . ARG B 1 246 ? -22.236 1.034   -13.242 1   35.16  ? 238  ARG B CZ  1 
ATOM   5950 N  NH1 . ARG B 1 246 ? -21.305 0.41    -12.5   1   30.073 ? 238  ARG B NH1 1 
ATOM   5951 N  NH2 . ARG B 1 246 ? -22.243 0.851   -14.563 1   35.818 ? 238  ARG B NH2 1 
ATOM   5952 N  N   . ASP B 1 247 ? -27.658 3.781   -7.927  1   20.361 ? 239  ASP B N   1 
ATOM   5953 C  CA  . ASP B 1 247 ? -28.467 3.238   -6.83   1   19.389 ? 239  ASP B CA  1 
ATOM   5954 C  C   . ASP B 1 247 ? -29.801 2.765   -7.39   1   22.254 ? 239  ASP B C   1 
ATOM   5955 O  O   . ASP B 1 247 ? -30.17  3.057   -8.543  1   20.826 ? 239  ASP B O   1 
ATOM   5956 C  CB  . ASP B 1 247 ? -28.586 4.151   -5.61   1   19.778 ? 239  ASP B CB  1 
ATOM   5957 C  CG  . ASP B 1 247 ? -29.359 5.452   -5.78   1   23.538 ? 239  ASP B CG  1 
ATOM   5958 O  OD1 . ASP B 1 247 ? -29.766 5.754   -6.921  1   26.311 ? 239  ASP B OD1 1 
ATOM   5959 O  OD2 . ASP B 1 247 ? -29.616 6.164   -4.776  1   23.805 ? 239  ASP B OD2 1 
ATOM   5960 N  N   . LEU B 1 248 ? -30.515 2.018   -6.567  1   19.535 ? 240  LEU B N   1 
ATOM   5961 C  CA  . LEU B 1 248 ? -31.832 1.471   -6.905  1   20.745 ? 240  LEU B CA  1 
ATOM   5962 C  C   . LEU B 1 248 ? -32.489 0.936   -5.635  1   21.848 ? 240  LEU B C   1 
ATOM   5963 O  O   . LEU B 1 248 ? -31.817 0.289   -4.821  1   19.512 ? 240  LEU B O   1 
ATOM   5964 C  CB  . LEU B 1 248 ? -31.736 0.323   -7.924  1   20.858 ? 240  LEU B CB  1 
ATOM   5965 C  CG  . LEU B 1 248 ? -33.085 -0.233  -8.426  1   20.538 ? 240  LEU B CG  1 
ATOM   5966 C  CD1 . LEU B 1 248 ? -33.795 0.768   -9.349  1   24.892 ? 240  LEU B CD1 1 
ATOM   5967 C  CD2 . LEU B 1 248 ? -32.787 -1.521  -9.188  1   23.077 ? 240  LEU B CD2 1 
ATOM   5968 N  N   . TRP B 1 249 ? -33.787 1.188   -5.479  1   19.794 ? 241  TRP B N   1 
ATOM   5969 C  CA  . TRP B 1 249 ? -34.602 0.563   -4.437  1   21.774 ? 241  TRP B CA  1 
ATOM   5970 C  C   . TRP B 1 249 ? -35.298 -0.657  -5.017  1   23.042 ? 241  TRP B C   1 
ATOM   5971 O  O   . TRP B 1 249 ? -35.883 -0.612  -6.109  1   22.426 ? 241  TRP B O   1 
ATOM   5972 C  CB  . TRP B 1 249 ? -35.612 1.554   -3.85   1   20.043 ? 241  TRP B CB  1 
ATOM   5973 C  CG  . TRP B 1 249 ? -34.937 2.598   -2.995  1   21.728 ? 241  TRP B CG  1 
ATOM   5974 C  CD1 . TRP B 1 249 ? -34.414 3.789   -3.391  1   21.951 ? 241  TRP B CD1 1 
ATOM   5975 C  CD2 . TRP B 1 249 ? -34.713 2.528   -1.573  1   22.471 ? 241  TRP B CD2 1 
ATOM   5976 N  NE1 . TRP B 1 249 ? -33.888 4.471   -2.326  1   22.918 ? 241  TRP B NE1 1 
ATOM   5977 C  CE2 . TRP B 1 249 ? -34.075 3.733   -1.191  1   23.105 ? 241  TRP B CE2 1 
ATOM   5978 C  CE3 . TRP B 1 249 ? -35.031 1.57    -0.593  1   23.72  ? 241  TRP B CE3 1 
ATOM   5979 C  CZ2 . TRP B 1 249 ? -33.714 4.002   0.135   1   22.223 ? 241  TRP B CZ2 1 
ATOM   5980 C  CZ3 . TRP B 1 249 ? -34.681 1.841   0.713   1   25.871 ? 241  TRP B CZ3 1 
ATOM   5981 C  CH2 . TRP B 1 249 ? -34.047 3.036   1.064   1   23.093 ? 241  TRP B CH2 1 
ATOM   5982 N  N   . LEU B 1 250 ? -35.273 -1.768  -4.281  1   19.719 ? 242  LEU B N   1 
ATOM   5983 C  CA  . LEU B 1 250 ? -35.9   -3.034  -4.68   1   19.995 ? 242  LEU B CA  1 
ATOM   5984 C  C   . LEU B 1 250 ? -36.354 -3.755  -3.405  1   22.206 ? 242  LEU B C   1 
ATOM   5985 O  O   . LEU B 1 250 ? -36.364 -3.154  -2.318  1   21.415 ? 242  LEU B O   1 
ATOM   5986 C  CB  . LEU B 1 250 ? -34.96  -3.888  -5.528  1   22.619 ? 242  LEU B CB  1 
ATOM   5987 C  CG  . LEU B 1 250 ? -33.626 -4.265  -4.85   1   20.764 ? 242  LEU B CG  1 
ATOM   5988 C  CD1 . LEU B 1 250 ? -33.277 -5.727  -5.051  1   21.368 ? 242  LEU B CD1 1 
ATOM   5989 C  CD2 . LEU B 1 250 ? -32.452 -3.411  -5.339  1   24.091 ? 242  LEU B CD2 1 
ATOM   5990 N  N   . GLU B 1 251 ? -36.774 -5.015  -3.553  1   23.17  ? 243  GLU B N   1 
ATOM   5991 C  CA  . GLU B 1 251 ? -37.219 -5.803  -2.413  1   23.974 ? 243  GLU B CA  1 
ATOM   5992 C  C   . GLU B 1 251 ? -36.658 -7.201  -2.542  1   23.253 ? 243  GLU B C   1 
ATOM   5993 O  O   . GLU B 1 251 ? -36.359 -7.67   -3.646  1   26.46  ? 243  GLU B O   1 
ATOM   5994 C  CB  . GLU B 1 251 ? -38.739 -5.917  -2.263  1   24.916 ? 243  GLU B CB  1 
ATOM   5995 C  CG  . GLU B 1 251 ? -39.397 -4.654  -1.715  1   37.873 ? 243  GLU B CG  1 
ATOM   5996 C  CD  . GLU B 1 251 ? -40.914 -4.638  -1.736  1   46.131 ? 243  GLU B CD  1 
ATOM   5997 O  OE1 . GLU B 1 251 ? -41.468 -4.498  -2.839  1   45.059 ? 243  GLU B OE1 1 
ATOM   5998 O  OE2 . GLU B 1 251 ? -41.529 -4.752  -0.658  1   52.612 ? 243  GLU B OE2 1 
ATOM   5999 N  N   . ALA B 1 252 ? -36.5   -7.864  -1.37   1   20.584 ? 244  ALA B N   1 
ATOM   6000 C  CA  . ALA B 1 252 ? -36.188 -9.284  -1.352  1   21.26  ? 244  ALA B CA  1 
ATOM   6001 C  C   . ALA B 1 252 ? -37.49  -10.08  -1.385  1   19.765 ? 244  ALA B C   1 
ATOM   6002 O  O   . ALA B 1 252 ? -38.522 -9.556  -0.992  1   22.816 ? 244  ALA B O   1 
ATOM   6003 C  CB  . ALA B 1 252 ? -35.368 -9.612  -0.094  1   22.04  ? 244  ALA B CB  1 
ATOM   6004 N  N   . PRO B 1 253 ? -37.494 -11.356 -1.839  1   21.154 ? 245  PRO B N   1 
ATOM   6005 C  CA  . PRO B 1 253 ? -38.751 -12.125 -1.864  1   22.901 ? 245  PRO B CA  1 
ATOM   6006 C  C   . PRO B 1 253 ? -39.402 -12.409 -0.509  1   27.147 ? 245  PRO B C   1 
ATOM   6007 O  O   . PRO B 1 253 ? -40.618 -12.595 -0.438  1   27.673 ? 245  PRO B O   1 
ATOM   6008 C  CB  . PRO B 1 253 ? -38.369 -13.413 -2.598  1   23.959 ? 245  PRO B CB  1 
ATOM   6009 C  CG  . PRO B 1 253 ? -36.875 -13.541 -2.36   1   26.211 ? 245  PRO B CG  1 
ATOM   6010 C  CD  . PRO B 1 253 ? -36.386 -12.103 -2.453  1   22.092 ? 245  PRO B CD  1 
ATOM   6011 N  N   . TRP B 1 254 ? -38.572 -12.456 0.546   1   22.638 ? 246  TRP B N   1 
ATOM   6012 C  CA  . TRP B 1 254 ? -39.027 -12.507 1.933   1   21.574 ? 246  TRP B CA  1 
ATOM   6013 C  C   . TRP B 1 254 ? -38.031 -11.652 2.737   1   21.62  ? 246  TRP B C   1 
ATOM   6014 O  O   . TRP B 1 254 ? -37.021 -11.248 2.152   1   21.777 ? 246  TRP B O   1 
ATOM   6015 C  CB  . TRP B 1 254 ? -39.166 -13.966 2.443   1   22.969 ? 246  TRP B CB  1 
ATOM   6016 C  CG  . TRP B 1 254 ? -37.88  -14.682 2.791   1   22.16  ? 246  TRP B CG  1 
ATOM   6017 C  CD1 . TRP B 1 254 ? -37.283 -14.728 4.032   1   22.41  ? 246  TRP B CD1 1 
ATOM   6018 C  CD2 . TRP B 1 254 ? -37.069 -15.499 1.919   1   20.687 ? 246  TRP B CD2 1 
ATOM   6019 N  NE1 . TRP B 1 254 ? -36.143 -15.482 3.959   1   23.057 ? 246  TRP B NE1 1 
ATOM   6020 C  CE2 . TRP B 1 254 ? -35.982 -15.982 2.691   1   21.34  ? 246  TRP B CE2 1 
ATOM   6021 C  CE3 . TRP B 1 254 ? -37.159 -15.874 0.559   1   20.643 ? 246  TRP B CE3 1 
ATOM   6022 C  CZ2 . TRP B 1 254 ? -34.998 -16.822 2.153   1   20.74  ? 246  TRP B CZ2 1 
ATOM   6023 C  CZ3 . TRP B 1 254 ? -36.182 -16.681 0.027   1   21.201 ? 246  TRP B CZ3 1 
ATOM   6024 C  CH2 . TRP B 1 254 ? -35.094 -17.127 0.801   1   20.719 ? 246  TRP B CH2 1 
ATOM   6025 N  N   . CYS B 1 255 ? -38.329 -11.346 4.01    1   22.78  ? 247  CYS B N   1 
ATOM   6026 C  CA  . CYS B 1 255 ? -37.329 -10.633 4.8     1   23.501 ? 247  CYS B CA  1 
ATOM   6027 C  C   . CYS B 1 255 ? -36.265 -11.649 5.216   1   23.464 ? 247  CYS B C   1 
ATOM   6028 O  O   . CYS B 1 255 ? -36.434 -12.389 6.203   1   20.852 ? 247  CYS B O   1 
ATOM   6029 C  CB  . CYS B 1 255 ? -37.888 -9.774  5.941   1   24.965 ? 247  CYS B CB  1 
ATOM   6030 S  SG  . CYS B 1 255 ? -36.549 -8.806  6.722   1   23.951 ? 247  CYS B SG  1 
ATOM   6031 N  N   . ALA B 1 256 ? -35.19  -11.663 4.438   1   21.902 ? 248  ALA B N   1 
ATOM   6032 C  CA  . ALA B 1 256 ? -34.154 -12.668 4.498   1   19.166 ? 248  ALA B CA  1 
ATOM   6033 C  C   . ALA B 1 256 ? -32.866 -12.084 5.077   1   18.103 ? 248  ALA B C   1 
ATOM   6034 O  O   . ALA B 1 256 ? -32.628 -10.887 4.964   1   17.72  ? 248  ALA B O   1 
ATOM   6035 C  CB  . ALA B 1 256 ? -33.904 -13.218 3.099   1   19.069 ? 248  ALA B CB  1 
ATOM   6036 N  N   . PHE B 1 257 ? -31.988 -12.979 5.557   1   18.298 ? 249  PHE B N   1 
ATOM   6037 C  CA  . PHE B 1 257 ? -30.707 -12.577 6.122   1   16.634 ? 249  PHE B CA  1 
ATOM   6038 C  C   . PHE B 1 257 ? -29.732 -12.566 4.934   1   16.448 ? 249  PHE B C   1 
ATOM   6039 O  O   . PHE B 1 257 ? -29.253 -13.63  4.523   1   17.554 ? 249  PHE B O   1 
ATOM   6040 C  CB  . PHE B 1 257 ? -30.403 -13.643 7.192   1   16.136 ? 249  PHE B CB  1 
ATOM   6041 C  CG  . PHE B 1 257 ? -29.273 -13.339 8.171   1   18.78  ? 249  PHE B CG  1 
ATOM   6042 C  CD1 . PHE B 1 257 ? -28.199 -12.5   7.86    1   17.202 ? 249  PHE B CD1 1 
ATOM   6043 C  CD2 . PHE B 1 257 ? -29.298 -13.925 9.438   1   18.307 ? 249  PHE B CD2 1 
ATOM   6044 C  CE1 . PHE B 1 257 ? -27.189 -12.259 8.791   1   17.332 ? 249  PHE B CE1 1 
ATOM   6045 C  CE2 . PHE B 1 257 ? -28.287 -13.688 10.359  1   18.244 ? 249  PHE B CE2 1 
ATOM   6046 C  CZ  . PHE B 1 257 ? -27.237 -12.82  10.053  1   19.285 ? 249  PHE B CZ  1 
ATOM   6047 N  N   . ILE B 1 258 ? -29.476 -11.354 4.436   1   17.012 ? 250  ILE B N   1 
ATOM   6048 C  CA  . ILE B 1 258 ? -28.626 -11.199 3.247   1   17.672 ? 250  ILE B CA  1 
ATOM   6049 C  C   . ILE B 1 258 ? -27.233 -10.731 3.701   1   15.603 ? 250  ILE B C   1 
ATOM   6050 O  O   . ILE B 1 258 ? -26.935 -9.524  3.679   1   15.335 ? 250  ILE B O   1 
ATOM   6051 C  CB  . ILE B 1 258 ? -29.24  -10.23  2.212   1   18.654 ? 250  ILE B CB  1 
ATOM   6052 C  CG1 . ILE B 1 258 ? -30.73  -10.55  1.974   1   19.178 ? 250  ILE B CG1 1 
ATOM   6053 C  CG2 . ILE B 1 258 ? -28.427 -10.353 0.917   1   18.663 ? 250  ILE B CG2 1 
ATOM   6054 C  CD1 . ILE B 1 258 ? -31.42  -9.675  0.936   1   20.853 ? 250  ILE B CD1 1 
ATOM   6055 N  N   . HIS B 1 259 ? -26.431 -11.697 4.114   1   15.788 ? 251  HIS B N   1 
ATOM   6056 C  CA  . HIS B 1 259 ? -25.172 -11.367 4.769   1   16.627 ? 251  HIS B CA  1 
ATOM   6057 C  C   . HIS B 1 259 ? -24.135 -10.88  3.739   1   17.015 ? 251  HIS B C   1 
ATOM   6058 O  O   . HIS B 1 259 ? -23.379 -9.94   4.005   1   15.839 ? 251  HIS B O   1 
ATOM   6059 C  CB  . HIS B 1 259 ? -24.647 -12.603 5.527   1   14.764 ? 251  HIS B CB  1 
ATOM   6060 C  CG  . HIS B 1 259 ? -23.379 -12.305 6.245   1   15.399 ? 251  HIS B CG  1 
ATOM   6061 N  ND1 . HIS B 1 259 ? -23.346 -11.359 7.247   1   16.953 ? 251  HIS B ND1 1 
ATOM   6062 C  CD2 . HIS B 1 259 ? -22.113 -12.718 6.05    1   16.039 ? 251  HIS B CD2 1 
ATOM   6063 C  CE1 . HIS B 1 259 ? -22.085 -11.28  7.674   1   16.148 ? 251  HIS B CE1 1 
ATOM   6064 N  NE2 . HIS B 1 259 ? -21.303 -12.105 7       1   16.051 ? 251  HIS B NE2 1 
ATOM   6065 N  N   . ASP B 1 260 ? -24.015 -11.591 2.617   1   18.344 ? 252  ASP B N   1 
ATOM   6066 C  CA  . ASP B 1 260 ? -22.894 -11.377 1.725   1   16.489 ? 252  ASP B CA  1 
ATOM   6067 C  C   . ASP B 1 260 ? -23.439 -11.389 0.294   1   18.715 ? 252  ASP B C   1 
ATOM   6068 O  O   . ASP B 1 260 ? -24.622 -11.538 0.057   1   18.733 ? 252  ASP B O   1 
ATOM   6069 C  CB  . ASP B 1 260 ? -21.806 -12.416 1.998   1   17.412 ? 252  ASP B CB  1 
ATOM   6070 C  CG  . ASP B 1 260 ? -20.398 -12.195 1.436   1   16.532 ? 252  ASP B CG  1 
ATOM   6071 O  OD1 . ASP B 1 260 ? -20.154 -11.12  0.81    1   17.215 ? 252  ASP B OD1 1 
ATOM   6072 O  OD2 . ASP B 1 260 ? -19.544 -13.071 1.619   1   17.254 ? 252  ASP B OD2 1 
ATOM   6073 N  N   . CYS B 1 261 ? -22.532 -11.107 -0.641  1   17.354 ? 253  CYS B N   1 
ATOM   6074 C  CA  . CYS B 1 261 ? -22.893 -10.904 -2.047  1   16.578 ? 253  CYS B CA  1 
ATOM   6075 C  C   . CYS B 1 261 ? -21.665 -11.257 -2.885  1   16.899 ? 253  CYS B C   1 
ATOM   6076 O  O   . CYS B 1 261 ? -20.568 -11.522 -2.364  1   17.958 ? 253  CYS B O   1 
ATOM   6077 C  CB  . CYS B 1 261 ? -23.347 -9.455  -2.279  1   17.883 ? 253  CYS B CB  1 
ATOM   6078 S  SG  . CYS B 1 261 ? -22.045 -8.225  -1.953  1   18.16  ? 253  CYS B SG  1 
ATOM   6079 N  N   . ALA B 1 262 ? -21.843 -11.232 -4.234  1   17.81  ? 254  ALA B N   1 
ATOM   6080 C  CA  . ALA B 1 262 ? -20.684 -11.352 -5.112  1   17.837 ? 254  ALA B CA  1 
ATOM   6081 C  C   . ALA B 1 262 ? -20.765 -10.292 -6.192  1   18.261 ? 254  ALA B C   1 
ATOM   6082 O  O   . ALA B 1 262 ? -21.866 -10.033 -6.701  1   18.681 ? 254  ALA B O   1 
ATOM   6083 C  CB  . ALA B 1 262 ? -20.698 -12.71  -5.808  1   20.687 ? 254  ALA B CB  1 
ATOM   6084 N  N   . LEU B 1 263 ? -19.601 -9.724  -6.532  1   18.576 ? 255  LEU B N   1 
ATOM   6085 C  CA  . LEU B 1 263 ? -19.488 -8.664  -7.536  1   18.157 ? 255  LEU B CA  1 
ATOM   6086 C  C   . LEU B 1 263 ? -18.874 -9.272  -8.797  1   18.829 ? 255  LEU B C   1 
ATOM   6087 O  O   . LEU B 1 263 ? -17.859 -9.941  -8.732  1   19.32  ? 255  LEU B O   1 
ATOM   6088 C  CB  . LEU B 1 263 ? -18.563 -7.551  -7.059  1   19.059 ? 255  LEU B CB  1 
ATOM   6089 C  CG  . LEU B 1 263 ? -18.44  -6.378  -8.029  1   18.992 ? 255  LEU B CG  1 
ATOM   6090 C  CD1 . LEU B 1 263 ? -19.765 -5.629  -8.109  1   16.636 ? 255  LEU B CD1 1 
ATOM   6091 C  CD2 . LEU B 1 263 ? -17.333 -5.469  -7.564  1   21.697 ? 255  LEU B CD2 1 
ATOM   6092 N  N   . THR B 1 264 ? -19.555 -8.992  -9.936  1   19.251 ? 256  THR B N   1 
ATOM   6093 C  CA  . THR B 1 264 ? -19.062 -9.415  -11.245 1   21.566 ? 256  THR B CA  1 
ATOM   6094 C  C   . THR B 1 264 ? -19.007 -8.162  -12.12  1   20.117 ? 256  THR B C   1 
ATOM   6095 O  O   . THR B 1 264 ? -19.495 -7.1    -11.717 1   20.629 ? 256  THR B O   1 
ATOM   6096 C  CB  . THR B 1 264 ? -19.937 -10.516 -11.87  1   20.655 ? 256  THR B CB  1 
ATOM   6097 O  OG1 . THR B 1 264 ? -21.114 -9.92   -12.41  1   20.468 ? 256  THR B OG1 1 
ATOM   6098 C  CG2 . THR B 1 264 ? -20.241 -11.648 -10.901 1   21.287 ? 256  THR B CG2 1 
ATOM   6099 N  N   . PRO B 1 265 ? -18.472 -8.212  -13.368 1   21.603 ? 257  PRO B N   1 
ATOM   6100 C  CA  . PRO B 1 265 ? -18.441 -6.969  -14.141 1   20.715 ? 257  PRO B CA  1 
ATOM   6101 C  C   . PRO B 1 265 ? -19.784 -6.299  -14.351 1   19.441 ? 257  PRO B C   1 
ATOM   6102 O  O   . PRO B 1 265 ? -19.836 -5.076  -14.361 1   21.54  ? 257  PRO B O   1 
ATOM   6103 C  CB  . PRO B 1 265 ? -17.783 -7.415  -15.465 1   21.397 ? 257  PRO B CB  1 
ATOM   6104 C  CG  . PRO B 1 265 ? -16.949 -8.6    -15.059 1   23.227 ? 257  PRO B CG  1 
ATOM   6105 C  CD  . PRO B 1 265 ? -17.742 -9.336  -13.994 1   22.077 ? 257  PRO B CD  1 
ATOM   6106 N  N   . ASN B 1 266 ? -20.856 -7.092  -14.508 1   20.274 ? 258  ASN B N   1 
ATOM   6107 C  CA  . ASN B 1 266 ? -22.156 -6.533  -14.863 1   20.753 ? 258  ASN B CA  1 
ATOM   6108 C  C   . ASN B 1 266 ? -23.254 -6.788  -13.828 1   21.224 ? 258  ASN B C   1 
ATOM   6109 O  O   . ASN B 1 266 ? -24.392 -6.333  -14.02  1   20.398 ? 258  ASN B O   1 
ATOM   6110 C  CB  . ASN B 1 266 ? -22.609 -7.098  -16.216 1   22.475 ? 258  ASN B CB  1 
ATOM   6111 C  CG  . ASN B 1 266 ? -21.594 -6.781  -17.305 1   26.723 ? 258  ASN B CG  1 
ATOM   6112 O  OD1 . ASN B 1 266 ? -21.353 -5.603  -17.585 1   26.74  ? 258  ASN B OD1 1 
ATOM   6113 N  ND2 . ASN B 1 266 ? -20.93  -7.795  -17.833 1   22.94  ? 258  ASN B ND2 1 
ATOM   6114 N  N   . TYR B 1 267 ? -22.894 -7.395  -12.663 1   19.95  ? 259  TYR B N   1 
ATOM   6115 C  CA  . TYR B 1 267 ? -23.92  -7.723  -11.672 1   18.946 ? 259  TYR B CA  1 
ATOM   6116 C  C   . TYR B 1 267 ? -23.379 -7.551  -10.246 1   17.552 ? 259  TYR B C   1 
ATOM   6117 O  O   . TYR B 1 267 ? -22.195 -7.744  -10.001 1   20.022 ? 259  TYR B O   1 
ATOM   6118 C  CB  . TYR B 1 267 ? -24.37  -9.192  -11.742 1   20.028 ? 259  TYR B CB  1 
ATOM   6119 C  CG  . TYR B 1 267 ? -25.138 -9.557  -13.008 1   22.123 ? 259  TYR B CG  1 
ATOM   6120 C  CD1 . TYR B 1 267 ? -26.519 -9.375  -13.078 1   23.083 ? 259  TYR B CD1 1 
ATOM   6121 C  CD2 . TYR B 1 267 ? -24.478 -10.102 -14.096 1   25.016 ? 259  TYR B CD2 1 
ATOM   6122 C  CE1 . TYR B 1 267 ? -27.239 -9.724  -14.22  1   26.955 ? 259  TYR B CE1 1 
ATOM   6123 C  CE2 . TYR B 1 267 ? -25.176 -10.453 -15.244 1   23.863 ? 259  TYR B CE2 1 
ATOM   6124 C  CZ  . TYR B 1 267 ? -26.556 -10.277 -15.291 1   28.547 ? 259  TYR B CZ  1 
ATOM   6125 O  OH  . TYR B 1 267 ? -27.265 -10.626 -16.429 1   31.238 ? 259  TYR B OH  1 
ATOM   6126 N  N   . LEU B 1 268 ? -24.302 -7.162  -9.361  1   18.513 ? 260  LEU B N   1 
ATOM   6127 C  CA  . LEU B 1 268 ? -24.139 -7.445  -7.937  1   18.302 ? 260  LEU B CA  1 
ATOM   6128 C  C   . LEU B 1 268 ? -25.141 -8.533  -7.595  1   19.25  ? 260  LEU B C   1 
ATOM   6129 O  O   . LEU B 1 268 ? -26.317 -8.428  -7.962  1   19.633 ? 260  LEU B O   1 
ATOM   6130 C  CB  . LEU B 1 268 ? -24.372 -6.204  -7.087  1   18.736 ? 260  LEU B CB  1 
ATOM   6131 C  CG  . LEU B 1 268 ? -24.196 -6.441  -5.574  1   18.137 ? 260  LEU B CG  1 
ATOM   6132 C  CD1 . LEU B 1 268 ? -22.734 -6.758  -5.24   1   18.955 ? 260  LEU B CD1 1 
ATOM   6133 C  CD2 . LEU B 1 268 ? -24.754 -5.208  -4.844  1   18.553 ? 260  LEU B CD2 1 
ATOM   6134 N  N   . VAL B 1 269 ? -24.65  -9.617  -6.975  1   18.539 ? 261  VAL B N   1 
ATOM   6135 C  CA  . VAL B 1 269 ? -25.498 -10.787 -6.738  1   19.174 ? 261  VAL B CA  1 
ATOM   6136 C  C   . VAL B 1 269 ? -25.631 -10.968 -5.221  1   18.198 ? 261  VAL B C   1 
ATOM   6137 O  O   . VAL B 1 269 ? -24.633 -11.272 -4.577  1   18.63  ? 261  VAL B O   1 
ATOM   6138 C  CB  . VAL B 1 269 ? -24.975 -12.073 -7.388  1   18.487 ? 261  VAL B CB  1 
ATOM   6139 C  CG1 . VAL B 1 269 ? -26.007 -13.193 -7.29   1   19.279 ? 261  VAL B CG1 1 
ATOM   6140 C  CG2 . VAL B 1 269 ? -24.582 -11.843 -8.845  1   20.085 ? 261  VAL B CG2 1 
ATOM   6141 N  N   . LEU B 1 270 ? -26.851 -10.802 -4.702  1   17.777 ? 262  LEU B N   1 
ATOM   6142 C  CA  . LEU B 1 270 ? -27.097 -10.95  -3.257  1   17.675 ? 262  LEU B CA  1 
ATOM   6143 C  C   . LEU B 1 270 ? -27.299 -12.425 -2.938  1   21.517 ? 262  LEU B C   1 
ATOM   6144 O  O   . LEU B 1 270 ? -28.004 -13.119 -3.674  1   19.655 ? 262  LEU B O   1 
ATOM   6145 C  CB  . LEU B 1 270 ? -28.325 -10.145 -2.852  1   17.123 ? 262  LEU B CB  1 
ATOM   6146 C  CG  . LEU B 1 270 ? -28.316 -8.661  -3.257  1   21.803 ? 262  LEU B CG  1 
ATOM   6147 C  CD1 . LEU B 1 270 ? -29.38  -7.831  -2.604  1   18.841 ? 262  LEU B CD1 1 
ATOM   6148 C  CD2 . LEU B 1 270 ? -26.98  -7.942  -3.088  1   21.391 ? 262  LEU B CD2 1 
ATOM   6149 N  N   . MET B 1 271 ? -26.828 -12.875 -1.778  1   18.197 ? 263  MET B N   1 
ATOM   6150 C  CA  . MET B 1 271 ? -26.905 -14.268 -1.343  1   17.766 ? 263  MET B CA  1 
ATOM   6151 C  C   . MET B 1 271 ? -27.833 -14.334 -0.122  1   20.515 ? 263  MET B C   1 
ATOM   6152 O  O   . MET B 1 271 ? -27.529 -13.743 0.919   1   18.893 ? 263  MET B O   1 
ATOM   6153 C  CB  . MET B 1 271 ? -25.508 -14.787 -0.986  1   18.568 ? 263  MET B CB  1 
ATOM   6154 C  CG  . MET B 1 271 ? -25.389 -16.274 -0.728  1   19.511 ? 263  MET B CG  1 
ATOM   6155 S  SD  . MET B 1 271 ? -23.688 -16.84  -0.716  1   19.679 ? 263  MET B SD  1 
ATOM   6156 C  CE  . MET B 1 271 ? -22.945 -15.884 0.631   1   18.61  ? 263  MET B CE  1 
ATOM   6157 N  N   . LEU B 1 272 ? -29.001 -14.99  -0.25   1   17.874 ? 264  LEU B N   1 
ATOM   6158 C  CA  . LEU B 1 272 ? -29.988 -15.038 0.829   1   18.747 ? 264  LEU B CA  1 
ATOM   6159 C  C   . LEU B 1 272 ? -29.846 -16.33  1.614   1   21.329 ? 264  LEU B C   1 
ATOM   6160 O  O   . LEU B 1 272 ? -29.958 -17.44  1.056   1   20.334 ? 264  LEU B O   1 
ATOM   6161 C  CB  . LEU B 1 272 ? -31.422 -14.945 0.285   1   17.852 ? 264  LEU B CB  1 
ATOM   6162 C  CG  . LEU B 1 272 ? -31.914 -13.556 -0.118  1   19.351 ? 264  LEU B CG  1 
ATOM   6163 C  CD1 . LEU B 1 272 ? -31.042 -12.895 -1.199  1   18.335 ? 264  LEU B CD1 1 
ATOM   6164 C  CD2 . LEU B 1 272 ? -33.431 -13.578 -0.56   1   20.814 ? 264  LEU B CD2 1 
ATOM   6165 N  N   . TRP B 1 273 ? -29.573 -16.161 2.911   1   17.718 ? 265  TRP B N   1 
ATOM   6166 C  CA  . TRP B 1 273 ? -29.628 -17.306 3.813   1   18.849 ? 265  TRP B CA  1 
ATOM   6167 C  C   . TRP B 1 273 ? -31.08  -17.63  4.134   1   19.681 ? 265  TRP B C   1 
ATOM   6168 O  O   . TRP B 1 273 ? -31.925 -16.737 4.159   1   19.067 ? 265  TRP B O   1 
ATOM   6169 C  CB  . TRP B 1 273 ? -28.9   -16.95  5.121   1   17.284 ? 265  TRP B CB  1 
ATOM   6170 C  CG  . TRP B 1 273 ? -27.424 -16.714 4.985   1   17.723 ? 265  TRP B CG  1 
ATOM   6171 C  CD1 . TRP B 1 273 ? -26.577 -16.956 3.926   1   19.158 ? 265  TRP B CD1 1 
ATOM   6172 C  CD2 . TRP B 1 273 ? -26.594 -16.243 6.066   1   17.512 ? 265  TRP B CD2 1 
ATOM   6173 N  NE1 . TRP B 1 273 ? -25.292 -16.593 4.25    1   19.536 ? 265  TRP B NE1 1 
ATOM   6174 C  CE2 . TRP B 1 273 ? -25.271 -16.191 5.565   1   18.169 ? 265  TRP B CE2 1 
ATOM   6175 C  CE3 . TRP B 1 273 ? -26.849 -15.885 7.41    1   17.102 ? 265  TRP B CE3 1 
ATOM   6176 C  CZ2 . TRP B 1 273 ? -24.19  -15.797 6.361   1   18.958 ? 265  TRP B CZ2 1 
ATOM   6177 C  CZ3 . TRP B 1 273 ? -25.774 -15.494 8.197   1   19.172 ? 265  TRP B CZ3 1 
ATOM   6178 C  CH2 . TRP B 1 273 ? -24.478 -15.458 7.669   1   18.898 ? 265  TRP B CH2 1 
ATOM   6179 N  N   . PRO B 1 274 ? -31.376 -18.912 4.472   1   19.085 ? 266  PRO B N   1 
ATOM   6180 C  CA  . PRO B 1 274 ? -32.729 -19.362 4.827   1   20.573 ? 266  PRO B CA  1 
ATOM   6181 C  C   . PRO B 1 274 ? -33.159 -19.032 6.252   1   21.89  ? 266  PRO B C   1 
ATOM   6182 O  O   . PRO B 1 274 ? -33.522 -19.923 7.027   1   21.229 ? 266  PRO B O   1 
ATOM   6183 C  CB  . PRO B 1 274 ? -32.591 -20.909 4.577   1   20.751 ? 266  PRO B CB  1 
ATOM   6184 C  CG  . PRO B 1 274 ? -31.196 -21.215 5.069   1   20.568 ? 266  PRO B CG  1 
ATOM   6185 C  CD  . PRO B 1 274 ? -30.441 -20.044 4.395   1   20.723 ? 266  PRO B CD  1 
ATOM   6186 N  N   . PHE B 1 275 ? -33.035 -17.756 6.613   1   19.976 ? 267  PHE B N   1 
ATOM   6187 C  CA  . PHE B 1 275 ? -33.633 -17.249 7.835   1   18.666 ? 267  PHE B CA  1 
ATOM   6188 C  C   . PHE B 1 275 ? -34.7   -16.252 7.437   1   21.385 ? 267  PHE B C   1 
ATOM   6189 O  O   . PHE B 1 275 ? -34.535 -15.512 6.453   1   20.399 ? 267  PHE B O   1 
ATOM   6190 C  CB  . PHE B 1 275 ? -32.649 -16.532 8.781   1   19.135 ? 267  PHE B CB  1 
ATOM   6191 C  CG  . PHE B 1 275 ? -31.473 -17.36  9.271   1   18.97  ? 267  PHE B CG  1 
ATOM   6192 C  CD1 . PHE B 1 275 ? -30.359 -17.59  8.457   1   17.838 ? 267  PHE B CD1 1 
ATOM   6193 C  CD2 . PHE B 1 275 ? -31.482 -17.96  10.547  1   17.684 ? 267  PHE B CD2 1 
ATOM   6194 C  CE1 . PHE B 1 275 ? -29.275 -18.368 8.869   1   20.096 ? 267  PHE B CE1 1 
ATOM   6195 C  CE2 . PHE B 1 275 ? -30.416 -18.768 10.943  1   18.294 ? 267  PHE B CE2 1 
ATOM   6196 C  CZ  . PHE B 1 275 ? -29.335 -18.997 10.118  1   20.012 ? 267  PHE B CZ  1 
ATOM   6197 N  N   . GLU B 1 276 ? -35.745 -16.162 8.253   1   20.185 ? 268  GLU B N   1 
ATOM   6198 C  CA  . GLU B 1 276 ? -36.774 -15.163 8.033   1   21.662 ? 268  GLU B CA  1 
ATOM   6199 C  C   . GLU B 1 276 ? -36.962 -14.354 9.305   1   21.769 ? 268  GLU B C   1 
ATOM   6200 O  O   . GLU B 1 276 ? -36.866 -14.903 10.408  1   21.254 ? 268  GLU B O   1 
ATOM   6201 C  CB  . GLU B 1 276 ? -38.071 -15.84  7.569   1   23.325 ? 268  GLU B CB  1 
ATOM   6202 C  CG  . GLU B 1 276 ? -39.168 -14.837 7.199   1   26.689 ? 268  GLU B CG  1 
ATOM   6203 C  CD  . GLU B 1 276 ? -40.328 -15.424 6.387   1   29.906 ? 268  GLU B CD  1 
ATOM   6204 O  OE1 . GLU B 1 276 ? -40.434 -16.655 6.316   1   29.985 ? 268  GLU B OE1 1 
ATOM   6205 O  OE2 . GLU B 1 276 ? -41.086 -14.644 5.766   1   31.587 ? 268  GLU B OE2 1 
ATOM   6206 N  N   . ALA B 1 277 ? -37.204 -13.058 9.125   1   20.608 ? 269  ALA B N   1 
ATOM   6207 C  CA  . ALA B 1 277 ? -37.512 -12.101 10.179  1   20.722 ? 269  ALA B CA  1 
ATOM   6208 C  C   . ALA B 1 277 ? -39.017 -12.04  10.386  1   24.017 ? 269  ALA B C   1 
ATOM   6209 O  O   . ALA B 1 277 ? -39.783 -12.086 9.411   1   23.928 ? 269  ALA B O   1 
ATOM   6210 C  CB  . ALA B 1 277 ? -36.992 -10.725 9.807   1   19.965 ? 269  ALA B CB  1 
ATOM   6211 N  N   . ASN B 1 278 ? -39.424 -11.907 11.646  1   23.06  ? 270  ASN B N   1 
ATOM   6212 C  CA  . ASN B 1 278 ? -40.837 -11.83  11.984  1   25.159 ? 270  ASN B CA  1 
ATOM   6213 C  C   . ASN B 1 278 ? -41.027 -10.767 13.054  1   22.225 ? 270  ASN B C   1 
ATOM   6214 O  O   . ASN B 1 278 ? -40.504 -10.924 14.159  1   20.519 ? 270  ASN B O   1 
ATOM   6215 C  CB  . ASN B 1 278 ? -41.286 -13.208 12.46   1   22.74  ? 270  ASN B CB  1 
ATOM   6216 C  CG  . ASN B 1 278 ? -42.782 -13.255 12.663  1   25.402 ? 270  ASN B CG  1 
ATOM   6217 O  OD1 . ASN B 1 278 ? -43.324 -12.727 13.634  1   25.765 ? 270  ASN B OD1 1 
ATOM   6218 N  ND2 . ASN B 1 278 ? -43.484 -13.852 11.714  1   33.933 ? 270  ASN B ND2 1 
ATOM   6219 N  N   . LEU B 1 279 ? -41.752 -9.679  12.747  1   20.957 ? 271  LEU B N   1 
ATOM   6220 C  CA  . LEU B 1 279 ? -41.991 -8.576  13.668  1   19.869 ? 271  LEU B CA  1 
ATOM   6221 C  C   . LEU B 1 279 ? -42.776 -9.034  14.908  1   23.558 ? 271  LEU B C   1 
ATOM   6222 O  O   . LEU B 1 279 ? -42.46  -8.615  16.023  1   20.425 ? 271  LEU B O   1 
ATOM   6223 C  CB  . LEU B 1 279 ? -42.668 -7.396  12.964  1   21.073 ? 271  LEU B CB  1 
ATOM   6224 C  CG  . LEU B 1 279 ? -42.882 -6.116  13.789  1   23.447 ? 271  LEU B CG  1 
ATOM   6225 C  CD1 . LEU B 1 279 ? -41.531 -5.478  14.169  1   23.369 ? 271  LEU B CD1 1 
ATOM   6226 C  CD2 . LEU B 1 279 ? -43.728 -5.125  12.985  1   24.215 ? 271  LEU B CD2 1 
ATOM   6227 N  N   . GLU B 1 280 ? -43.818 -9.882  14.717  1   24.195 ? 272  GLU B N   1 
ATOM   6228 C  CA  . GLU B 1 280 ? -44.608 -10.347 15.86   1   25.809 ? 272  GLU B CA  1 
ATOM   6229 C  C   . GLU B 1 280 ? -43.729 -11.115 16.865  1   20.311 ? 272  GLU B C   1 
ATOM   6230 O  O   . GLU B 1 280 ? -43.84  -10.884 18.073  1   23.945 ? 272  GLU B O   1 
ATOM   6231 C  CB  . GLU B 1 280 ? -45.843 -11.121 15.364  1   31.135 ? 272  GLU B CB  1 
ATOM   6232 C  CG  . GLU B 1 280 ? -46.736 -11.669 16.484  1   46.736 ? 272  GLU B CG  1 
ATOM   6233 C  CD  . GLU B 1 280 ? -48.066 -12.38  16.19   1   61.757 ? 272  GLU B CD  1 
ATOM   6234 O  OE1 . GLU B 1 280 ? -48.259 -12.9   15.068  1   62.015 ? 272  GLU B OE1 1 
ATOM   6235 O  OE2 . GLU B 1 280 ? -48.937 -12.394 17.094  1   60.055 ? 272  GLU B OE2 1 
ATOM   6236 N  N   . ARG B 1 281 ? -42.877 -12.004 16.344  1   20.64  ? 273  ARG B N   1 
ATOM   6237 C  CA  . ARG B 1 281 ? -41.927 -12.751 17.18   1   20.05  ? 273  ARG B CA  1 
ATOM   6238 C  C   . ARG B 1 281 ? -41.047 -11.783 17.999  1   19.624 ? 273  ARG B C   1 
ATOM   6239 O  O   . ARG B 1 281 ? -40.825 -11.965 19.212  1   20.121 ? 273  ARG B O   1 
ATOM   6240 C  CB  . ARG B 1 281 ? -41.082 -13.753 16.388  1   20.621 ? 273  ARG B CB  1 
ATOM   6241 C  CG  . ARG B 1 281 ? -40.015 -14.458 17.228  1   18.837 ? 273  ARG B CG  1 
ATOM   6242 C  CD  . ARG B 1 281 ? -39.309 -15.585 16.476  1   18.84  ? 273  ARG B CD  1 
ATOM   6243 N  NE  . ARG B 1 281 ? -38.57  -15.062 15.32   1   21.232 ? 273  ARG B NE  1 
ATOM   6244 C  CZ  . ARG B 1 281 ? -38.753 -15.298 14.03   1   22.032 ? 273  ARG B CZ  1 
ATOM   6245 N  NH1 . ARG B 1 281 ? -39.636 -16.193 13.627  1   23.905 ? 273  ARG B NH1 1 
ATOM   6246 N  NH2 . ARG B 1 281 ? -38.036 -14.643 13.126  1   20.745 ? 273  ARG B NH2 1 
ATOM   6247 N  N   . MET B 1 282 ? -40.53  -10.745 17.323  1   19.036 ? 274  MET B N   1 
ATOM   6248 C  CA  . MET B 1 282 ? -39.666 -9.779  18.001  1   17.105 ? 274  MET B CA  1 
ATOM   6249 C  C   . MET B 1 282 ? -40.44  -9.054  19.098  1   17.718 ? 274  MET B C   1 
ATOM   6250 O  O   . MET B 1 282 ? -39.93  -8.864  20.197  1   19.236 ? 274  MET B O   1 
ATOM   6251 C  CB  . MET B 1 282 ? -39.042 -8.823  16.981  1   16.673 ? 274  MET B CB  1 
ATOM   6252 C  CG  . MET B 1 282 ? -37.991 -9.557  16.194  1   17.53  ? 274  MET B CG  1 
ATOM   6253 S  SD  . MET B 1 282 ? -37.154 -8.361  15.138  1   21.212 ? 274  MET B SD  1 
ATOM   6254 C  CE  . MET B 1 282 ? -37.773 -8.717  13.495  1   18.313 ? 274  MET B CE  1 
ATOM   6255 N  N   . LYS B 1 283 ? -41.68  -8.617  18.78   1   20.853 ? 275  LYS B N   1 
ATOM   6256 C  CA  . LYS B 1 283 ? -42.451 -7.902  19.789  1   20.219 ? 275  LYS B CA  1 
ATOM   6257 C  C   . LYS B 1 283 ? -42.778 -8.777  21.013  1   19.017 ? 275  LYS B C   1 
ATOM   6258 O  O   . LYS B 1 283 ? -42.873 -8.229  22.105  1   22.022 ? 275  LYS B O   1 
ATOM   6259 C  CB  . LYS B 1 283 ? -43.72  -7.31   19.172  1   23.307 ? 275  LYS B CB  1 
ATOM   6260 C  CG  . LYS B 1 283 ? -43.522 -6.103  18.262  1   25.436 ? 275  LYS B CG  1 
ATOM   6261 C  CD  . LYS B 1 283 ? -44.882 -5.603  17.771  1   24.352 ? 275  LYS B CD  1 
ATOM   6262 C  CE  . LYS B 1 283 ? -44.803 -4.286  17.106  1   26.092 ? 275  LYS B CE  1 
ATOM   6263 N  NZ  . LYS B 1 283 ? -46.05  -4.09   16.313  1   34.262 ? 275  LYS B NZ  1 
ATOM   6264 N  N   . ALA B 1 284 ? -42.844 -10.108 20.814  1   19.789 ? 276  ALA B N   1 
ATOM   6265 C  CA  . ALA B 1 284 ? -43.068 -11.096 21.862  1   21.799 ? 276  ALA B CA  1 
ATOM   6266 C  C   . ALA B 1 284 ? -41.763 -11.398 22.597  1   28.08  ? 276  ALA B C   1 
ATOM   6267 O  O   . ALA B 1 284 ? -41.766 -12.237 23.482  1   29.027 ? 276  ALA B O   1 
ATOM   6268 C  CB  . ALA B 1 284 ? -43.638 -12.369 21.258  1   22.835 ? 276  ALA B CB  1 
ATOM   6269 N  N   . GLY B 1 285 ? -40.655 -10.741 22.209  1   22.199 ? 277  GLY B N   1 
ATOM   6270 C  CA  . GLY B 1 285 ? -39.396 -10.864 22.938  1   20.227 ? 277  GLY B CA  1 
ATOM   6271 C  C   . GLY B 1 285 ? -38.467 -11.954 22.385  1   20.243 ? 277  GLY B C   1 
ATOM   6272 O  O   . GLY B 1 285 ? -37.491 -12.324 23.044  1   20.52  ? 277  GLY B O   1 
ATOM   6273 N  N   . GLY B 1 286 ? -38.768 -12.492 21.196  1   20.381 ? 278  GLY B N   1 
ATOM   6274 C  CA  . GLY B 1 286 ? -37.964 -13.546 20.599  1   18.6   ? 278  GLY B CA  1 
ATOM   6275 C  C   . GLY B 1 286 ? -36.943 -12.995 19.598  1   16.781 ? 278  GLY B C   1 
ATOM   6276 O  O   . GLY B 1 286 ? -36.833 -11.771 19.392  1   17.856 ? 278  GLY B O   1 
ATOM   6277 N  N   . HIS B 1 287 ? -36.221 -13.941 19.003  1   16.681 ? 279  HIS B N   1 
ATOM   6278 C  CA  . HIS B 1 287 ? -35.13  -13.634 18.079  1   16.881 ? 279  HIS B CA  1 
ATOM   6279 C  C   . HIS B 1 287 ? -35.645 -12.938 16.819  1   17.664 ? 279  HIS B C   1 
ATOM   6280 O  O   . HIS B 1 287 ? -36.749 -13.201 16.324  1   19.029 ? 279  HIS B O   1 
ATOM   6281 C  CB  . HIS B 1 287 ? -34.294 -14.882 17.771  1   18.067 ? 279  HIS B CB  1 
ATOM   6282 C  CG  . HIS B 1 287 ? -33.204 -15.099 18.762  1   17.9   ? 279  HIS B CG  1 
ATOM   6283 N  ND1 . HIS B 1 287 ? -32.978 -16.29  19.438  1   21.183 ? 279  HIS B ND1 1 
ATOM   6284 C  CD2 . HIS B 1 287 ? -32.328 -14.208 19.261  1   16.304 ? 279  HIS B CD2 1 
ATOM   6285 C  CE1 . HIS B 1 287 ? -31.922 -16.115 20.277  1   17.029 ? 279  HIS B CE1 1 
ATOM   6286 N  NE2 . HIS B 1 287 ? -31.53  -14.855 20.158  1   22.21  ? 279  HIS B NE2 1 
ATOM   6287 N  N   . HIS B 1 288 ? -34.78  -12.091 16.25   1   16.611 ? 280  HIS B N   1 
ATOM   6288 C  CA  . HIS B 1 288 ? -35.061 -11.468 14.969  1   16.128 ? 280  HIS B CA  1 
ATOM   6289 C  C   . HIS B 1 288 ? -35.217 -12.544 13.891  1   16.374 ? 280  HIS B C   1 
ATOM   6290 O  O   . HIS B 1 288 ? -36.206 -12.502 13.144  1   18.216 ? 280  HIS B O   1 
ATOM   6291 C  CB  . HIS B 1 288 ? -33.903 -10.518 14.617  1   16.188 ? 280  HIS B CB  1 
ATOM   6292 C  CG  . HIS B 1 288 ? -34.094 -9.692  13.376  1   15.581 ? 280  HIS B CG  1 
ATOM   6293 N  ND1 . HIS B 1 288 ? -34.234 -8.329  13.497  1   16.091 ? 280  HIS B ND1 1 
ATOM   6294 C  CD2 . HIS B 1 288 ? -34.125 -10.006 12.035  1   16.52  ? 280  HIS B CD2 1 
ATOM   6295 C  CE1 . HIS B 1 288 ? -34.378 -7.789  12.27   1   16.057 ? 280  HIS B CE1 1 
ATOM   6296 N  NE2 . HIS B 1 288 ? -34.26  -8.778  11.361  1   15.895 ? 280  HIS B NE2 1 
ATOM   6297 N  N   . TRP B 1 289 ? -34.253 -13.458 13.781  1   16.033 ? 281  TRP B N   1 
ATOM   6298 C  CA  . TRP B 1 289 ? -34.175 -14.479 12.752  1   16.847 ? 281  TRP B CA  1 
ATOM   6299 C  C   . TRP B 1 289 ? -34.566 -15.85  13.287  1   19.965 ? 281  TRP B C   1 
ATOM   6300 O  O   . TRP B 1 289 ? -34.258 -16.171 14.439  1   20.974 ? 281  TRP B O   1 
ATOM   6301 C  CB  . TRP B 1 289 ? -32.723 -14.617 12.259  1   19.084 ? 281  TRP B CB  1 
ATOM   6302 C  CG  . TRP B 1 289 ? -32.172 -13.375 11.618  1   17.067 ? 281  TRP B CG  1 
ATOM   6303 C  CD1 . TRP B 1 289 ? -31.15  -12.593 12.098  1   16.079 ? 281  TRP B CD1 1 
ATOM   6304 C  CD2 . TRP B 1 289 ? -32.659 -12.725 10.423  1   17.314 ? 281  TRP B CD2 1 
ATOM   6305 N  NE1 . TRP B 1 289 ? -30.938 -11.532 11.246  1   16.415 ? 281  TRP B NE1 1 
ATOM   6306 C  CE2 . TRP B 1 289 ? -31.84  -11.594 10.207  1   19.175 ? 281  TRP B CE2 1 
ATOM   6307 C  CE3 . TRP B 1 289 ? -33.666 -13.028 9.487   1   18.052 ? 281  TRP B CE3 1 
ATOM   6308 C  CZ2 . TRP B 1 289 ? -32.025 -10.721 9.127   1   19.382 ? 281  TRP B CZ2 1 
ATOM   6309 C  CZ3 . TRP B 1 289 ? -33.859 -12.157 8.431   1   20.96  ? 281  TRP B CZ3 1 
ATOM   6310 C  CH2 . TRP B 1 289 ? -33.073 -11.007 8.268   1   20.818 ? 281  TRP B CH2 1 
ATOM   6311 N  N   . ALA B 1 290 ? -35.183 -16.663 12.409  1   19.053 ? 282  ALA B N   1 
ATOM   6312 C  CA  . ALA B 1 290 ? -35.395 -18.084 12.656  1   20.186 ? 282  ALA B CA  1 
ATOM   6313 C  C   . ALA B 1 290 ? -35.04  -18.843 11.395  1   21.409 ? 282  ALA B C   1 
ATOM   6314 O  O   . ALA B 1 290 ? -35.488 -18.471 10.314  1   20.984 ? 282  ALA B O   1 
ATOM   6315 C  CB  . ALA B 1 290 ? -36.839 -18.345 13.029  1   19.712 ? 282  ALA B CB  1 
ATOM   6316 N  N   . TYR B 1 291 ? -34.246 -19.89  11.523  1   19.421 ? 283  TYR B N   1 
ATOM   6317 C  CA  . TYR B 1 291 ? -33.856 -20.746 10.41   1   20.509 ? 283  TYR B CA  1 
ATOM   6318 C  C   . TYR B 1 291 ? -35.108 -21.433 9.867   1   20.626 ? 283  TYR B C   1 
ATOM   6319 O  O   . TYR B 1 291 ? -35.958 -21.839 10.662  1   22.052 ? 283  TYR B O   1 
ATOM   6320 C  CB  . TYR B 1 291 ? -32.827 -21.783 10.876  1   19.593 ? 283  TYR B CB  1 
ATOM   6321 C  CG  . TYR B 1 291 ? -32.199 -22.569 9.738   1   19.308 ? 283  TYR B CG  1 
ATOM   6322 C  CD1 . TYR B 1 291 ? -32.783 -23.741 9.251   1   20.48  ? 283  TYR B CD1 1 
ATOM   6323 C  CD2 . TYR B 1 291 ? -31.044 -22.097 9.101   1   18.507 ? 283  TYR B CD2 1 
ATOM   6324 C  CE1 . TYR B 1 291 ? -32.199 -24.455 8.206   1   18.998 ? 283  TYR B CE1 1 
ATOM   6325 C  CE2 . TYR B 1 291 ? -30.443 -22.804 8.068   1   20.226 ? 283  TYR B CE2 1 
ATOM   6326 C  CZ  . TYR B 1 291 ? -31.053 -23.965 7.586   1   20.449 ? 283  TYR B CZ  1 
ATOM   6327 O  OH  . TYR B 1 291 ? -30.429 -24.628 6.556   1   22.56  ? 283  TYR B OH  1 
ATOM   6328 N  N   . ASP B 1 292 ? -35.2   -21.563 8.542   1   22.693 ? 284  ASP B N   1 
ATOM   6329 C  CA  . ASP B 1 292 ? -36.338 -22.268 7.957   1   24.632 ? 284  ASP B CA  1 
ATOM   6330 C  C   . ASP B 1 292 ? -35.833 -23.299 6.946   1   26.119 ? 284  ASP B C   1 
ATOM   6331 O  O   . ASP B 1 292 ? -35.342 -22.937 5.885   1   22.525 ? 284  ASP B O   1 
ATOM   6332 C  CB  . ASP B 1 292 ? -37.36  -21.254 7.464   1   22.269 ? 284  ASP B CB  1 
ATOM   6333 C  CG  . ASP B 1 292 ? -38.615 -21.836 6.828   1   25.023 ? 284  ASP B CG  1 
ATOM   6334 O  OD1 . ASP B 1 292 ? -38.698 -23.092 6.717   1   26.158 ? 284  ASP B OD1 1 
ATOM   6335 O  OD2 . ASP B 1 292 ? -39.453 -21.011 6.431   1   28.686 ? 284  ASP B OD2 1 
ATOM   6336 N  N   . TYR B 1 293 ? -35.981 -24.595 7.281   1   23.978 ? 285  TYR B N   1 
ATOM   6337 C  CA  . TYR B 1 293 ? -35.61  -25.708 6.411   1   24.867 ? 285  TYR B CA  1 
ATOM   6338 C  C   . TYR B 1 293 ? -36.359 -25.709 5.065   1   24.014 ? 285  TYR B C   1 
ATOM   6339 O  O   . TYR B 1 293 ? -35.845 -26.319 4.131   1   27.093 ? 285  TYR B O   1 
ATOM   6340 C  CB  . TYR B 1 293 ? -35.863 -27.039 7.133   1   25.131 ? 285  TYR B CB  1 
ATOM   6341 C  CG  . TYR B 1 293 ? -34.747 -27.352 8.112   1   23.112 ? 285  TYR B CG  1 
ATOM   6342 C  CD1 . TYR B 1 293 ? -33.529 -27.848 7.653   1   26.808 ? 285  TYR B CD1 1 
ATOM   6343 C  CD2 . TYR B 1 293 ? -34.914 -27.147 9.494   1   24.124 ? 285  TYR B CD2 1 
ATOM   6344 C  CE1 . TYR B 1 293 ? -32.494 -28.152 8.52    1   26.891 ? 285  TYR B CE1 1 
ATOM   6345 C  CE2 . TYR B 1 293 ? -33.899 -27.465 10.384  1   25.158 ? 285  TYR B CE2 1 
ATOM   6346 C  CZ  . TYR B 1 293 ? -32.681 -27.944 9.888   1   29.953 ? 285  TYR B CZ  1 
ATOM   6347 O  OH  . TYR B 1 293 ? -31.652 -28.3   10.708  1   32.776 ? 285  TYR B OH  1 
ATOM   6348 N  N   . THR B 1 294 ? -37.5   -25.027 4.975   1   26.112 ? 286  THR B N   1 
ATOM   6349 C  CA  . THR B 1 294 ? -38.298 -24.991 3.749   1   26.665 ? 286  THR B CA  1 
ATOM   6350 C  C   . THR B 1 294 ? -37.826 -23.897 2.785   1   30.344 ? 286  THR B C   1 
ATOM   6351 O  O   . THR B 1 294 ? -38.325 -23.828 1.652   1   30.472 ? 286  THR B O   1 
ATOM   6352 C  CB  . THR B 1 294 ? -39.806 -24.853 4.003   1   27.28  ? 286  THR B CB  1 
ATOM   6353 O  OG1 . THR B 1 294 ? -40.172 -23.522 4.352   1   34.201 ? 286  THR B OG1 1 
ATOM   6354 C  CG2 . THR B 1 294 ? -40.386 -25.853 4.988   1   27.467 ? 286  THR B CG2 1 
ATOM   6355 N  N   . LYS B 1 295 ? -36.944 -22.982 3.24    1   25.962 ? 287  LYS B N   1 
ATOM   6356 C  CA  . LYS B 1 295 ? -36.477 -21.903 2.378   1   24.306 ? 287  LYS B CA  1 
ATOM   6357 C  C   . LYS B 1 295 ? -35.299 -22.401 1.554   1   23.696 ? 287  LYS B C   1 
ATOM   6358 O  O   . LYS B 1 295 ? -34.346 -22.978 2.099   1   23.896 ? 287  LYS B O   1 
ATOM   6359 C  CB  . LYS B 1 295 ? -36.06  -20.639 3.148   1   24.885 ? 287  LYS B CB  1 
ATOM   6360 C  CG  . LYS B 1 295 ? -37.157 -19.809 3.813   1   25.886 ? 287  LYS B CG  1 
ATOM   6361 C  CD  . LYS B 1 295 ? -38.066 -19.131 2.79    1   29.757 ? 287  LYS B CD  1 
ATOM   6362 C  CE  . LYS B 1 295 ? -38.989 -18.235 3.554   1   27.084 ? 287  LYS B CE  1 
ATOM   6363 N  NZ  . LYS B 1 295 ? -40.156 -17.863 2.775   1   37.056 ? 287  LYS B NZ  1 
ATOM   6364 N  N   . PRO B 1 296 ? -35.269 -22.19  0.213   1   21.485 ? 288  PRO B N   1 
ATOM   6365 C  CA  . PRO B 1 296 ? -34.09  -22.57  -0.562  1   21.871 ? 288  PRO B CA  1 
ATOM   6366 C  C   . PRO B 1 296 ? -33.1   -21.412 -0.488  1   20.768 ? 288  PRO B C   1 
ATOM   6367 O  O   . PRO B 1 296 ? -33.516 -20.239 -0.362  1   21.361 ? 288  PRO B O   1 
ATOM   6368 C  CB  . PRO B 1 296 ? -34.687 -22.733 -2.001  1   22.792 ? 288  PRO B CB  1 
ATOM   6369 C  CG  . PRO B 1 296 ? -35.781 -21.684 -2.017  1   21.474 ? 288  PRO B CG  1 
ATOM   6370 C  CD  . PRO B 1 296 ? -36.384 -21.676 -0.616  1   24.559 ? 288  PRO B CD  1 
ATOM   6371 N  N   . ILE B 1 297 ? -31.814 -21.758 -0.594  1   21.447 ? 289  ILE B N   1 
ATOM   6372 C  CA  . ILE B 1 297 ? -30.802 -20.734 -0.88   1   20.003 ? 289  ILE B CA  1 
ATOM   6373 C  C   . ILE B 1 297 ? -31.286 -19.98  -2.117  1   21.579 ? 289  ILE B C   1 
ATOM   6374 O  O   . ILE B 1 297 ? -31.665 -20.605 -3.128  1   23.166 ? 289  ILE B O   1 
ATOM   6375 C  CB  . ILE B 1 297 ? -29.441 -21.385 -1.151  1   20.827 ? 289  ILE B CB  1 
ATOM   6376 C  CG1 . ILE B 1 297 ? -28.878 -22.016 0.158   1   19.724 ? 289  ILE B CG1 1 
ATOM   6377 C  CG2 . ILE B 1 297 ? -28.43  -20.427 -1.805  1   20.905 ? 289  ILE B CG2 1 
ATOM   6378 C  CD1 . ILE B 1 297 ? -27.735 -22.96  -0.093  1   18.914 ? 289  ILE B CD1 1 
ATOM   6379 N  N   . THR B 1 298 ? -31.315 -18.645 -2.011  1   19.339 ? 290  THR B N   1 
ATOM   6380 C  CA  . THR B 1 298 ? -31.873 -17.792 -3.051  1   20.09  ? 290  THR B CA  1 
ATOM   6381 C  C   . THR B 1 298 ? -30.822 -16.73  -3.375  1   21.71  ? 290  THR B C   1 
ATOM   6382 O  O   . THR B 1 298 ? -30.073 -16.299 -2.48   1   20.439 ? 290  THR B O   1 
ATOM   6383 C  CB  . THR B 1 298 ? -33.206 -17.214 -2.576  1   21.079 ? 290  THR B CB  1 
ATOM   6384 O  OG1 . THR B 1 298 ? -34.107 -18.315 -2.389  1   21.774 ? 290  THR B OG1 1 
ATOM   6385 C  CG2 . THR B 1 298 ? -33.867 -16.286 -3.581  1   20.48  ? 290  THR B CG2 1 
ATOM   6386 N  N   . TRP B 1 299 ? -30.768 -16.305 -4.641  1   21.396 ? 291  TRP B N   1 
ATOM   6387 C  CA  . TRP B 1 299 ? -29.834 -15.291 -5.115  1   22.137 ? 291  TRP B CA  1 
ATOM   6388 C  C   . TRP B 1 299 ? -30.648 -14.199 -5.791  1   24.816 ? 291  TRP B C   1 
ATOM   6389 O  O   . TRP B 1 299 ? -31.599 -14.488 -6.523  1   23.949 ? 291  TRP B O   1 
ATOM   6390 C  CB  . TRP B 1 299 ? -28.828 -15.865 -6.113  1   21.461 ? 291  TRP B CB  1 
ATOM   6391 C  CG  . TRP B 1 299 ? -28.034 -17.041 -5.606  1   20.798 ? 291  TRP B CG  1 
ATOM   6392 C  CD1 . TRP B 1 299 ? -28.389 -18.365 -5.638  1   22.235 ? 291  TRP B CD1 1 
ATOM   6393 C  CD2 . TRP B 1 299 ? -26.707 -16.993 -5.029  1   21.606 ? 291  TRP B CD2 1 
ATOM   6394 N  NE1 . TRP B 1 299 ? -27.379 -19.14  -5.134  1   23.019 ? 291  TRP B NE1 1 
ATOM   6395 C  CE2 . TRP B 1 299 ? -26.337 -18.332 -4.753  1   24.577 ? 291  TRP B CE2 1 
ATOM   6396 C  CE3 . TRP B 1 299 ? -25.791 -15.957 -4.751  1   20.695 ? 291  TRP B CE3 1 
ATOM   6397 C  CZ2 . TRP B 1 299 ? -25.102 -18.66  -4.191  1   24.079 ? 291  TRP B CZ2 1 
ATOM   6398 C  CZ3 . TRP B 1 299 ? -24.555 -16.277 -4.208  1   21.889 ? 291  TRP B CZ3 1 
ATOM   6399 C  CH2 . TRP B 1 299 ? -24.215 -17.625 -3.961  1   21.987 ? 291  TRP B CH2 1 
ATOM   6400 N  N   . ILE B 1 300 ? -30.257 -12.948 -5.566  1   19.608 ? 292  ILE B N   1 
ATOM   6401 C  CA  . ILE B 1 300 ? -30.863 -11.817 -6.265  1   19.054 ? 292  ILE B CA  1 
ATOM   6402 C  C   . ILE B 1 300 ? -29.818 -11.224 -7.193  1   20.176 ? 292  ILE B C   1 
ATOM   6403 O  O   . ILE B 1 300 ? -28.806 -10.698 -6.73   1   19.995 ? 292  ILE B O   1 
ATOM   6404 C  CB  . ILE B 1 300 ? -31.437 -10.749 -5.312  1   18.914 ? 292  ILE B CB  1 
ATOM   6405 C  CG1 . ILE B 1 300 ? -32.425 -11.347 -4.261  1   20.409 ? 292  ILE B CG1 1 
ATOM   6406 C  CG2 . ILE B 1 300 ? -32.027 -9.565  -6.083  1   22.348 ? 292  ILE B CG2 1 
ATOM   6407 C  CD1 . ILE B 1 300 ? -32.926 -10.323 -3.257  1   19.712 ? 292  ILE B CD1 1 
ATOM   6408 N  N   . THR B 1 301 ? -30.061 -11.304 -8.513  1   19.088 ? 293  THR B N   1 
ATOM   6409 C  CA  . THR B 1 301 ? -29.158 -10.664 -9.476  1   20.144 ? 293  THR B CA  1 
ATOM   6410 C  C   . THR B 1 301 ? -29.601 -9.23   -9.721  1   20.931 ? 293  THR B C   1 
ATOM   6411 O  O   . THR B 1 301 ? -30.762 -8.991  -10.068 1   21.85  ? 293  THR B O   1 
ATOM   6412 C  CB  . THR B 1 301 ? -29.039 -11.436 -10.8   1   20.241 ? 293  THR B CB  1 
ATOM   6413 O  OG1 . THR B 1 301 ? -30.362 -11.692 -11.298 1   22.729 ? 293  THR B OG1 1 
ATOM   6414 C  CG2 . THR B 1 301 ? -28.298 -12.743 -10.646 1   23.331 ? 293  THR B CG2 1 
ATOM   6415 N  N   . ILE B 1 302 ? -28.673 -8.284  -9.534  1   20.739 ? 294  ILE B N   1 
ATOM   6416 C  CA  . ILE B 1 302 ? -28.938 -6.873  -9.751  1   20.482 ? 294  ILE B CA  1 
ATOM   6417 C  C   . ILE B 1 302 ? -28.016 -6.422  -10.866 1   21.994 ? 294  ILE B C   1 
ATOM   6418 O  O   . ILE B 1 302 ? -26.806 -6.318  -10.657 1   20.547 ? 294  ILE B O   1 
ATOM   6419 C  CB  . ILE B 1 302 ? -28.765 -6.007  -8.482  1   20.492 ? 294  ILE B CB  1 
ATOM   6420 C  CG1 . ILE B 1 302 ? -29.578 -6.518  -7.304  1   19.966 ? 294  ILE B CG1 1 
ATOM   6421 C  CG2 . ILE B 1 302 ? -29.102 -4.544  -8.806  1   21.245 ? 294  ILE B CG2 1 
ATOM   6422 C  CD1 . ILE B 1 302 ? -29.236 -5.831  -5.972  1   21.268 ? 294  ILE B CD1 1 
ATOM   6423 N  N   . PRO B 1 303 ? -28.531 -6.17   -12.101 1   20.304 ? 295  PRO B N   1 
ATOM   6424 C  CA  . PRO B 1 303 ? -27.66  -5.611  -13.126 1   20.585 ? 295  PRO B CA  1 
ATOM   6425 C  C   . PRO B 1 303 ? -27.052 -4.298  -12.648 1   18.538 ? 295  PRO B C   1 
ATOM   6426 O  O   . PRO B 1 303 ? -27.768 -3.451  -12.128 1   19.676 ? 295  PRO B O   1 
ATOM   6427 C  CB  . PRO B 1 303 ? -28.638 -5.41   -14.307 1   20.904 ? 295  PRO B CB  1 
ATOM   6428 C  CG  . PRO B 1 303 ? -29.617 -6.514  -14.076 1   22.399 ? 295  PRO B CG  1 
ATOM   6429 C  CD  . PRO B 1 303 ? -29.917 -6.401  -12.565 1   20.643 ? 295  PRO B CD  1 
ATOM   6430 N  N   . ARG B 1 304 ? -25.728 -4.164  -12.815 1   19.237 ? 296  ARG B N   1 
ATOM   6431 C  CA  . ARG B 1 304 ? -25.116 -2.94   -12.296 1   20.367 ? 296  ARG B CA  1 
ATOM   6432 C  C   . ARG B 1 304 ? -25.62  -1.762  -13.12  1   23.112 ? 296  ARG B C   1 
ATOM   6433 O  O   . ARG B 1 304 ? -25.757 -1.888  -14.35  1   24.872 ? 296  ARG B O   1 
ATOM   6434 C  CB  . ARG B 1 304 ? -23.593 -3.065  -12.299 1   19.939 ? 296  ARG B CB  1 
ATOM   6435 C  CG  . ARG B 1 304 ? -23.108 -4.107  -11.275 1   19.856 ? 296  ARG B CG  1 
ATOM   6436 C  CD  . ARG B 1 304 ? -21.63  -4.398  -11.311 1   20.154 ? 296  ARG B CD  1 
ATOM   6437 N  NE  . ARG B 1 304 ? -20.892 -3.194  -10.884 1   19.025 ? 296  ARG B NE  1 
ATOM   6438 C  CZ  . ARG B 1 304 ? -19.551 -3.072  -10.943 1   18.938 ? 296  ARG B CZ  1 
ATOM   6439 N  NH1 . ARG B 1 304 ? -18.794 -4.081  -11.338 1   18.04  ? 296  ARG B NH1 1 
ATOM   6440 N  NH2 . ARG B 1 304 ? -18.957 -1.949  -10.513 1   18.38  ? 296  ARG B NH2 1 
ATOM   6441 N  N   . GLY B 1 305 ? -25.982 -0.681  -12.438 1   20.312 ? 297  GLY B N   1 
ATOM   6442 C  CA  . GLY B 1 305 ? -26.609 0.488   -13.037 1   23.251 ? 297  GLY B CA  1 
ATOM   6443 C  C   . GLY B 1 305 ? -28.066 0.262   -13.456 1   22.566 ? 297  GLY B C   1 
ATOM   6444 O  O   . GLY B 1 305 ? -28.631 1.072   -14.198 1   24.048 ? 297  GLY B O   1 
ATOM   6445 N  N   . ALA B 1 306 ? -28.736 -0.802  -12.966 1   22.721 ? 298  ALA B N   1 
ATOM   6446 C  CA  . ALA B 1 306 ? -30.16  -0.997  -13.222 1   21.782 ? 298  ALA B CA  1 
ATOM   6447 C  C   . ALA B 1 306 ? -30.966 0.235   -12.863 1   23.593 ? 298  ALA B C   1 
ATOM   6448 O  O   . ALA B 1 306 ? -30.671 0.882   -11.866 1   24.818 ? 298  ALA B O   1 
ATOM   6449 C  CB  . ALA B 1 306 ? -30.662 -2.197  -12.448 1   22.484 ? 298  ALA B CB  1 
ATOM   6450 N  N   . LYS B 1 307 ? -32.006 0.535   -13.653 1   19.758 ? 299  LYS B N   1 
ATOM   6451 C  CA  . LYS B 1 307 ? -32.871 1.673   -13.401 1   20.492 ? 299  LYS B CA  1 
ATOM   6452 C  C   . LYS B 1 307 ? -34.294 1.254   -13.032 1   18.795 ? 299  LYS B C   1 
ATOM   6453 O  O   . LYS B 1 307 ? -35.083 2.08    -12.592 1   23.988 ? 299  LYS B O   1 
ATOM   6454 C  CB  . LYS B 1 307 ? -32.843 2.615   -14.61  1   20.591 ? 299  LYS B CB  1 
ATOM   6455 C  CG  . LYS B 1 307 ? -31.488 3.216   -14.886 1   24.449 ? 299  LYS B CG  1 
ATOM   6456 C  CD  . LYS B 1 307 ? -31.031 4.128   -13.742 1   29.4   ? 299  LYS B CD  1 
ATOM   6457 C  CE  . LYS B 1 307 ? -29.657 4.659   -14.023 1   35.141 ? 299  LYS B CE  1 
ATOM   6458 N  NZ  . LYS B 1 307 ? -29.032 5.095   -12.765 1   41.989 ? 299  LYS B NZ  1 
ATOM   6459 N  N   . SER B 1 308 ? -34.613 -0.024  -13.235 1   23.21  ? 300  SER B N   1 
ATOM   6460 C  CA  . SER B 1 308 ? -35.903 -0.53   -12.821 1   25.191 ? 300  SER B CA  1 
ATOM   6461 C  C   . SER B 1 308 ? -35.704 -1.75   -11.945 1   23.663 ? 300  SER B C   1 
ATOM   6462 O  O   . SER B 1 308 ? -34.91  -2.61   -12.275 1   21.744 ? 300  SER B O   1 
ATOM   6463 C  CB  . SER B 1 308 ? -36.749 -0.899  -14.003 1   27.448 ? 300  SER B CB  1 
ATOM   6464 O  OG  . SER B 1 308 ? -37.996 -1.352  -13.493 1   30.352 ? 300  SER B OG  1 
ATOM   6465 N  N   . LYS B 1 309 ? -36.514 -1.836  -10.886 1   26.693 ? 301  LYS B N   1 
ATOM   6466 C  CA  . LYS B 1 309 ? -36.519 -3.061  -10.097 1   28.085 ? 301  LYS B CA  1 
ATOM   6467 C  C   . LYS B 1 309 ? -36.954 -4.27   -10.936 1   25.48  ? 301  LYS B C   1 
ATOM   6468 O  O   . LYS B 1 309 ? -36.625 -5.411  -10.616 1   26.48  ? 301  LYS B O   1 
ATOM   6469 C  CB  . LYS B 1 309 ? -37.24  -2.867  -8.76   1   28.684 ? 301  LYS B CB  1 
ATOM   6470 C  CG  . LYS B 1 309 ? -38.711 -2.625  -8.958  1   31.094 ? 301  LYS B CG  1 
ATOM   6471 C  CD  . LYS B 1 309 ? -39.387 -2.306  -7.629  1   34.26  ? 301  LYS B CD  1 
ATOM   6472 C  CE  . LYS B 1 309 ? -40.855 -2.579  -7.795  1   39.967 ? 301  LYS B CE  1 
ATOM   6473 N  NZ  . LYS B 1 309 ? -41.597 -1.725  -6.865  1   49.442 ? 301  LYS B NZ  1 
ATOM   6474 N  N   . ASP B 1 310 ? -37.649 -4.054  -12.068 1   29.003 ? 302  ASP B N   1 
ATOM   6475 C  CA  . ASP B 1 310 ? -38.014 -5.212  -12.872 1   25.679 ? 302  ASP B CA  1 
ATOM   6476 C  C   . ASP B 1 310 ? -36.829 -5.863  -13.592 1   25.195 ? 302  ASP B C   1 
ATOM   6477 O  O   . ASP B 1 310 ? -36.979 -6.923  -14.183 1   26.8   ? 302  ASP B O   1 
ATOM   6478 C  CB  . ASP B 1 310 ? -39.322 -5.01   -13.631 1   31.133 ? 302  ASP B CB  1 
ATOM   6479 C  CG  . ASP B 1 310 ? -39.245 -3.963  -14.721 1   36.371 ? 302  ASP B CG  1 
ATOM   6480 O  OD1 . ASP B 1 310 ? -38.106 -3.82   -15.307 1   25.961 ? 302  ASP B OD1 1 
ATOM   6481 O  OD2 . ASP B 1 310 ? -40.318 -3.304  -14.942 1   35.882 ? 302  ASP B OD2 1 
ATOM   6482 N  N   . GLU B 1 311 ? -35.622 -5.271  -13.545 1   21.912 ? 303  GLU B N   1 
ATOM   6483 C  CA  . GLU B 1 311 ? -34.414 -5.862  -14.094 1   21.343 ? 303  GLU B CA  1 
ATOM   6484 C  C   . GLU B 1 311 ? -33.792 -6.882  -13.137 1   19.155 ? 303  GLU B C   1 
ATOM   6485 O  O   . GLU B 1 311 ? -32.938 -7.665  -13.563 1   21.303 ? 303  GLU B O   1 
ATOM   6486 C  CB  . GLU B 1 311 ? -33.369 -4.777  -14.354 1   21.474 ? 303  GLU B CB  1 
ATOM   6487 C  CG  . GLU B 1 311 ? -33.78  -3.675  -15.347 1   23.16  ? 303  GLU B CG  1 
ATOM   6488 C  CD  . GLU B 1 311 ? -32.683 -2.639  -15.608 1   23.146 ? 303  GLU B CD  1 
ATOM   6489 O  OE1 . GLU B 1 311 ? -31.512 -2.984  -15.9   1   23.733 ? 303  GLU B OE1 1 
ATOM   6490 O  OE2 . GLU B 1 311 ? -33.028 -1.455  -15.491 1   23.757 ? 303  GLU B OE2 1 
ATOM   6491 N  N   . VAL B 1 312 ? -34.229 -6.839  -11.872 1   21.693 ? 304  VAL B N   1 
ATOM   6492 C  CA  . VAL B 1 312 ? -33.693 -7.738  -10.844 1   23.274 ? 304  VAL B CA  1 
ATOM   6493 C  C   . VAL B 1 312 ? -34.387 -9.094  -10.975 1   23.149 ? 304  VAL B C   1 
ATOM   6494 O  O   . VAL B 1 312 ? -35.578 -9.163  -11.303 1   24.054 ? 304  VAL B O   1 
ATOM   6495 C  CB  . VAL B 1 312 ? -34.029 -7.036  -9.514  1   27.275 ? 304  VAL B CB  1 
ATOM   6496 C  CG1 . VAL B 1 312 ? -33.957 -7.922  -8.276  1   29.871 ? 304  VAL B CG1 1 
ATOM   6497 C  CG2 . VAL B 1 312 ? -33.237 -5.764  -9.309  1   26.985 ? 304  VAL B CG2 1 
ATOM   6498 N  N   . LYS B 1 313 ? -33.624 -10.175 -10.79  1   22.279 ? 305  LYS B N   1 
ATOM   6499 C  CA  . LYS B 1 313 ? -34.215 -11.507 -10.841 1   22.655 ? 305  LYS B CA  1 
ATOM   6500 C  C   . LYS B 1 313 ? -33.872 -12.301 -9.582  1   23.419 ? 305  LYS B C   1 
ATOM   6501 O  O   . LYS B 1 313 ? -32.771 -12.121 -9.026  1   23.864 ? 305  LYS B O   1 
ATOM   6502 C  CB  . LYS B 1 313 ? -33.751 -12.294 -12.069 1   22.708 ? 305  LYS B CB  1 
ATOM   6503 C  CG  . LYS B 1 313 ? -34.41  -11.693 -13.317 1   28.705 ? 305  LYS B CG  1 
ATOM   6504 C  CD  . LYS B 1 313 ? -34.396 -12.479 -14.622 1   42.001 ? 305  LYS B CD  1 
ATOM   6505 C  CE  . LYS B 1 313 ? -34.777 -11.66  -15.846 1   42.24  ? 305  LYS B CE  1 
ATOM   6506 N  NZ  . LYS B 1 313 ? -35.914 -10.743 -15.639 1   46.645 ? 305  LYS B NZ  1 
ATOM   6507 N  N   . TYR B 1 314 ? -34.795 -13.18  -9.187  1   22.882 ? 306  TYR B N   1 
ATOM   6508 C  CA  . TYR B 1 314 ? -34.571 -14.093 -8.058  1   22.408 ? 306  TYR B CA  1 
ATOM   6509 C  C   . TYR B 1 314 ? -34.33  -15.508 -8.581  1   25.425 ? 306  TYR B C   1 
ATOM   6510 O  O   . TYR B 1 314 ? -35.064 -15.967 -9.473  1   26.248 ? 306  TYR B O   1 
ATOM   6511 C  CB  . TYR B 1 314 ? -35.787 -14.12  -7.141  1   21.386 ? 306  TYR B CB  1 
ATOM   6512 C  CG  . TYR B 1 314 ? -36.355 -12.799 -6.654  1   22.047 ? 306  TYR B CG  1 
ATOM   6513 C  CD1 . TYR B 1 314 ? -35.544 -11.664 -6.435  1   21.89  ? 306  TYR B CD1 1 
ATOM   6514 C  CD2 . TYR B 1 314 ? -37.696 -12.72  -6.286  1   23.83  ? 306  TYR B CD2 1 
ATOM   6515 C  CE1 . TYR B 1 314 ? -36.077 -10.476 -5.954  1   21.692 ? 306  TYR B CE1 1 
ATOM   6516 C  CE2 . TYR B 1 314 ? -38.239 -11.553 -5.782  1   23.84  ? 306  TYR B CE2 1 
ATOM   6517 C  CZ  . TYR B 1 314 ? -37.435 -10.423 -5.649  1   22.148 ? 306  TYR B CZ  1 
ATOM   6518 O  OH  . TYR B 1 314 ? -37.972 -9.307  -5.129  1   25.839 ? 306  TYR B OH  1 
ATOM   6519 N  N   . TRP B 1 315 ? -33.325 -16.2   -8.032  1   20.84  ? 307  TRP B N   1 
ATOM   6520 C  CA  . TRP B 1 315 ? -32.911 -17.535 -8.444  1   21.636 ? 307  TRP B CA  1 
ATOM   6521 C  C   . TRP B 1 315 ? -32.848 -18.417 -7.209  1   24.647 ? 307  TRP B C   1 
ATOM   6522 O  O   . TRP B 1 315 ? -32.5   -17.927 -6.144  1   23.268 ? 307  TRP B O   1 
ATOM   6523 C  CB  . TRP B 1 315 ? -31.507 -17.518 -9.065  1   20.744 ? 307  TRP B CB  1 
ATOM   6524 C  CG  . TRP B 1 315 ? -31.34  -16.492 -10.164 1   20.513 ? 307  TRP B CG  1 
ATOM   6525 C  CD1 . TRP B 1 315 ? -31.146 -15.152 -10.012 1   22.411 ? 307  TRP B CD1 1 
ATOM   6526 C  CD2 . TRP B 1 315 ? -31.368 -16.745 -11.579 1   22.959 ? 307  TRP B CD2 1 
ATOM   6527 N  NE1 . TRP B 1 315 ? -31.087 -14.519 -11.233 1   23.423 ? 307  TRP B NE1 1 
ATOM   6528 C  CE2 . TRP B 1 315 ? -31.203 -15.48  -12.208 1   22.166 ? 307  TRP B CE2 1 
ATOM   6529 C  CE3 . TRP B 1 315 ? -31.498 -17.913 -12.361 1   24.196 ? 307  TRP B CE3 1 
ATOM   6530 C  CZ2 . TRP B 1 315 ? -31.193 -15.339 -13.595 1   24.726 ? 307  TRP B CZ2 1 
ATOM   6531 C  CZ3 . TRP B 1 315 ? -31.476 -17.778 -13.742 1   27.131 ? 307  TRP B CZ3 1 
ATOM   6532 C  CH2 . TRP B 1 315 ? -31.339 -16.505 -14.337 1   27.387 ? 307  TRP B CH2 1 
ATOM   6533 N  N   . HIS B 1 316 ? -33.075 -19.731 -7.351  1   22.671 ? 308  HIS B N   1 
ATOM   6534 C  CA  . HIS B 1 316 ? -33.165 -20.553 -6.153  1   23.403 ? 308  HIS B CA  1 
ATOM   6535 C  C   . HIS B 1 316 ? -32.551 -21.92  -6.39   1   23.394 ? 308  HIS B C   1 
ATOM   6536 O  O   . HIS B 1 316 ? -32.54  -22.424 -7.508  1   24.121 ? 308  HIS B O   1 
ATOM   6537 C  CB  . HIS B 1 316 ? -34.6   -20.69  -5.62   1   21.006 ? 308  HIS B CB  1 
ATOM   6538 C  CG  . HIS B 1 316 ? -35.444 -21.531 -6.542  1   26.775 ? 308  HIS B CG  1 
ATOM   6539 N  ND1 . HIS B 1 316 ? -35.728 -22.878 -6.408  1   32.2   ? 308  HIS B ND1 1 
ATOM   6540 C  CD2 . HIS B 1 316 ? -36.016 -21.157 -7.702  1   26.7   ? 308  HIS B CD2 1 
ATOM   6541 C  CE1 . HIS B 1 316 ? -36.471 -23.283 -7.44   1   28.334 ? 308  HIS B CE1 1 
ATOM   6542 N  NE2 . HIS B 1 316 ? -36.644 -22.259 -8.24   1   29.496 ? 308  HIS B NE2 1 
ATOM   6543 N  N   . TRP B 1 317 ? -32.018 -22.507 -5.305  1   21.258 ? 309  TRP B N   1 
ATOM   6544 C  CA  . TRP B 1 317 ? -31.51  -23.868 -5.312  1   20.453 ? 309  TRP B CA  1 
ATOM   6545 C  C   . TRP B 1 317 ? -32.331 -24.676 -4.287  1   25.163 ? 309  TRP B C   1 
ATOM   6546 O  O   . TRP B 1 317 ? -33.517 -24.948 -4.525  1   24.025 ? 309  TRP B O   1 
ATOM   6547 C  CB  . TRP B 1 317 ? -29.995 -23.911 -5.053  1   23.051 ? 309  TRP B CB  1 
ATOM   6548 C  CG  . TRP B 1 317 ? -29.433 -25.304 -5.121  1   24.362 ? 309  TRP B CG  1 
ATOM   6549 C  CD1 . TRP B 1 317 ? -29.491 -26.202 -6.158  1   22.968 ? 309  TRP B CD1 1 
ATOM   6550 C  CD2 . TRP B 1 317 ? -28.781 -25.999 -4.045  1   23.618 ? 309  TRP B CD2 1 
ATOM   6551 N  NE1 . TRP B 1 317 ? -28.909 -27.392 -5.81   1   23.694 ? 309  TRP B NE1 1 
ATOM   6552 C  CE2 . TRP B 1 317 ? -28.451 -27.298 -4.509  1   24.334 ? 309  TRP B CE2 1 
ATOM   6553 C  CE3 . TRP B 1 317 ? -28.422 -25.637 -2.738  1   23.786 ? 309  TRP B CE3 1 
ATOM   6554 C  CZ2 . TRP B 1 317 ? -27.794 -28.247 -3.714  1   24.485 ? 309  TRP B CZ2 1 
ATOM   6555 C  CZ3 . TRP B 1 317 ? -27.766 -26.569 -1.965  1   27.169 ? 309  TRP B CZ3 1 
ATOM   6556 C  CH2 . TRP B 1 317 ? -27.448 -27.854 -2.435  1   25.402 ? 309  TRP B CH2 1 
ATOM   6557 N  N   . LYS B 1 318 ? -31.722 -25.017 -3.135  1   21.749 ? 310  LYS B N   1 
ATOM   6558 C  CA  . LYS B 1 318 ? -32.294 -25.894 -2.116  1   23.236 ? 310  LYS B CA  1 
ATOM   6559 C  C   . LYS B 1 318 ? -31.832 -25.346 -0.767  1   25.174 ? 310  LYS B C   1 
ATOM   6560 O  O   . LYS B 1 318 ? -30.983 -24.441 -0.721  1   23.347 ? 310  LYS B O   1 
ATOM   6561 C  CB  . LYS B 1 318 ? -31.772 -27.336 -2.293  1   24.877 ? 310  LYS B CB  1 
ATOM   6562 C  CG  . LYS B 1 318 ? -32.098 -28.041 -3.642  1   26.928 ? 310  LYS B CG  1 
ATOM   6563 C  CD  . LYS B 1 318 ? -31.409 -29.407 -3.733  1   36.226 ? 310  LYS B CD  1 
ATOM   6564 C  CE  . LYS B 1 318 ? -31.731 -30.231 -4.933  1   42.122 ? 310  LYS B CE  1 
ATOM   6565 N  NZ  . LYS B 1 318 ? -30.747 -31.28  -5.229  1   46.808 ? 310  LYS B NZ  1 
ATOM   6566 N  N   . ASN B 1 319 ? -32.405 -25.889 0.326   1   21.345 ? 311  ASN B N   1 
ATOM   6567 C  CA  . ASN B 1 319 ? -32.033 -25.431 1.659   1   22.938 ? 311  ASN B CA  1 
ATOM   6568 C  C   . ASN B 1 319 ? -30.563 -25.71  1.967   1   22.973 ? 311  ASN B C   1 
ATOM   6569 O  O   . ASN B 1 319 ? -30.002 -26.758 1.623   1   21.997 ? 311  ASN B O   1 
ATOM   6570 C  CB  . ASN B 1 319 ? -32.926 -26.071 2.714   1   21.763 ? 311  ASN B CB  1 
ATOM   6571 C  CG  . ASN B 1 319 ? -32.688 -25.466 4.095   1   21.271 ? 311  ASN B CG  1 
ATOM   6572 O  OD1 . ASN B 1 319 ? -32.11  -26.129 4.975   1   22.101 ? 311  ASN B OD1 1 
ATOM   6573 N  ND2 . ASN B 1 319 ? -33.082 -24.212 4.289   1   22.544 ? 311  ASN B ND2 1 
ATOM   6574 N  N   . GLY B 1 320 ? -29.95  -24.725 2.657   1   20.934 ? 312  GLY B N   1 
ATOM   6575 C  CA  . GLY B 1 320 ? -28.561 -24.802 3.1     1   21.126 ? 312  GLY B CA  1 
ATOM   6576 C  C   . GLY B 1 320 ? -28.111 -23.386 3.485   1   18.822 ? 312  GLY B C   1 
ATOM   6577 O  O   . GLY B 1 320 ? -28.892 -22.45  3.365   1   19.776 ? 312  GLY B O   1 
ATOM   6578 N  N   . MET B 1 321 ? -26.846 -23.281 3.891   1   19.893 ? 313  MET B N   1 
ATOM   6579 C  CA  . MET B 1 321 ? -26.315 -22.018 4.395   1   21.414 ? 313  MET B CA  1 
ATOM   6580 C  C   . MET B 1 321 ? -24.958 -21.744 3.769   1   18.032 ? 313  MET B C   1 
ATOM   6581 O  O   . MET B 1 321 ? -23.913 -22.221 4.248   1   19.942 ? 313  MET B O   1 
ATOM   6582 C  CB  . MET B 1 321 ? -26.255 -22.014 5.915   1   21.573 ? 313  MET B CB  1 
ATOM   6583 C  CG  . MET B 1 321 ? -25.933 -20.608 6.442   1   18.995 ? 313  MET B CG  1 
ATOM   6584 S  SD  . MET B 1 321 ? -26.4   -20.611 8.183   1   20.373 ? 313  MET B SD  1 
ATOM   6585 C  CE  . MET B 1 321 ? -25.418 -19.178 8.706   1   22.655 ? 313  MET B CE  1 
ATOM   6586 N  N   . PRO B 1 322 ? -24.92  -20.954 2.651   1   18.024 ? 314  PRO B N   1 
ATOM   6587 C  CA  . PRO B 1 322 ? -23.64  -20.555 2.052   1   18.433 ? 314  PRO B CA  1 
ATOM   6588 C  C   . PRO B 1 322 ? -23.229 -19.244 2.728   1   17.593 ? 314  PRO B C   1 
ATOM   6589 O  O   . PRO B 1 322 ? -23.958 -18.245 2.594   1   18.475 ? 314  PRO B O   1 
ATOM   6590 C  CB  . PRO B 1 322 ? -23.961 -20.383 0.549   1   19.368 ? 314  PRO B CB  1 
ATOM   6591 C  CG  . PRO B 1 322 ? -25.415 -19.98  0.567   1   20.262 ? 314  PRO B CG  1 
ATOM   6592 C  CD  . PRO B 1 322 ? -26.079 -20.451 1.902   1   17.794 ? 314  PRO B CD  1 
ATOM   6593 N  N   . ILE B 1 323 ? -22.186 -19.3   3.564   1   17.412 ? 315  ILE B N   1 
ATOM   6594 C  CA  . ILE B 1 323 ? -21.985 -18.204 4.513   1   17.167 ? 315  ILE B CA  1 
ATOM   6595 C  C   . ILE B 1 323 ? -21.309 -17.002 3.835   1   15.381 ? 315  ILE B C   1 
ATOM   6596 O  O   . ILE B 1 323 ? -21.815 -15.868 3.963   1   17.503 ? 315  ILE B O   1 
ATOM   6597 C  CB  . ILE B 1 323 ? -21.251 -18.725 5.76    1   18.177 ? 315  ILE B CB  1 
ATOM   6598 C  CG1 . ILE B 1 323 ? -22.037 -19.88  6.427   1   17.527 ? 315  ILE B CG1 1 
ATOM   6599 C  CG2 . ILE B 1 323 ? -20.951 -17.566 6.725   1   16.26  ? 315  ILE B CG2 1 
ATOM   6600 C  CD1 . ILE B 1 323 ? -21.166 -20.674 7.395   1   19.669 ? 315  ILE B CD1 1 
ATOM   6601 N  N   . HIS B 1 324 ? -20.192 -17.264 3.132   1   16.635 ? 316  HIS B N   1 
ATOM   6602 C  CA  . HIS B 1 324 ? -19.44  -16.204 2.489   1   16.144 ? 316  HIS B CA  1 
ATOM   6603 C  C   . HIS B 1 324 ? -19.058 -16.605 1.073   1   17.462 ? 316  HIS B C   1 
ATOM   6604 O  O   . HIS B 1 324 ? -18.72  -17.766 0.837   1   19.221 ? 316  HIS B O   1 
ATOM   6605 C  CB  . HIS B 1 324 ? -18.14  -15.913 3.248   1   17.286 ? 316  HIS B CB  1 
ATOM   6606 C  CG  . HIS B 1 324 ? -18.35  -15.14  4.533   1   16.155 ? 316  HIS B CG  1 
ATOM   6607 N  ND1 . HIS B 1 324 ? -18.099 -15.73  5.75    1   17.215 ? 316  HIS B ND1 1 
ATOM   6608 C  CD2 . HIS B 1 324 ? -18.806 -13.895 4.777   1   16.587 ? 316  HIS B CD2 1 
ATOM   6609 C  CE1 . HIS B 1 324 ? -18.444 -14.839 6.7     1   16.992 ? 316  HIS B CE1 1 
ATOM   6610 N  NE2 . HIS B 1 324 ? -18.85  -13.711 6.138   1   17.006 ? 316  HIS B NE2 1 
ATOM   6611 N  N   . THR B 1 325 ? -19.052 -15.599 0.196   1   17.749 ? 317  THR B N   1 
ATOM   6612 C  CA  . THR B 1 325 ? -18.47  -15.796 -1.135  1   19.477 ? 317  THR B CA  1 
ATOM   6613 C  C   . THR B 1 325 ? -16.959 -15.605 -1.083  1   17.706 ? 317  THR B C   1 
ATOM   6614 O  O   . THR B 1 325 ? -16.457 -14.798 -0.274  1   17.73  ? 317  THR B O   1 
ATOM   6615 C  CB  . THR B 1 325 ? -19.119 -14.871 -2.162  1   17.23  ? 317  THR B CB  1 
ATOM   6616 O  OG1 . THR B 1 325 ? -18.837 -13.522 -1.775  1   18.826 ? 317  THR B OG1 1 
ATOM   6617 C  CG2 . THR B 1 325 ? -20.622 -15.13  -2.272  1   16.89  ? 317  THR B CG2 1 
ATOM   6618 N  N   . ALA B 1 326 ? -16.215 -16.333 -1.933  1   16.39  ? 318  ALA B N   1 
ATOM   6619 C  CA  . ALA B 1 326 ? -14.841 -15.937 -2.236  1   16.902 ? 318  ALA B CA  1 
ATOM   6620 C  C   . ALA B 1 326 ? -14.91  -14.707 -3.145  1   18.976 ? 318  ALA B C   1 
ATOM   6621 O  O   . ALA B 1 326 ? -14.691 -13.58  -2.695  1   18.134 ? 318  ALA B O   1 
ATOM   6622 C  CB  . ALA B 1 326 ? -14.047 -17.114 -2.824  1   16.958 ? 318  ALA B CB  1 
ATOM   6623 N  N   . SER B 1 327 ? -15.328 -14.932 -4.408  1   18.749 ? 319  SER B N   1 
ATOM   6624 C  CA  . SER B 1 327 ? -15.77  -13.834 -5.259  1   18.349 ? 319  SER B CA  1 
ATOM   6625 C  C   . SER B 1 327 ? -16.611 -14.419 -6.399  1   20.59  ? 319  SER B C   1 
ATOM   6626 O  O   . SER B 1 327 ? -16.963 -15.602 -6.36   1   19.529 ? 319  SER B O   1 
ATOM   6627 C  CB  . SER B 1 327 ? -14.609 -12.926 -5.708  1   17.938 ? 319  SER B CB  1 
ATOM   6628 O  OG  . SER B 1 327 ? -15.141 -11.72  -6.241  1   19.517 ? 319  SER B OG  1 
ATOM   6629 N  N   . GLY B 1 328 ? -16.949 -13.562 -7.37   1   20.747 ? 320  GLY B N   1 
ATOM   6630 C  CA  . GLY B 1 328 ? -17.664 -14.007 -8.565  1   21.512 ? 320  GLY B CA  1 
ATOM   6631 C  C   . GLY B 1 328 ? -17.044 -13.409 -9.815  1   22.324 ? 320  GLY B C   1 
ATOM   6632 O  O   . GLY B 1 328 ? -16.192 -12.508 -9.756  1   22.057 ? 320  GLY B O   1 
ATOM   6633 N  N   . PHE B 1 329 ? -17.499 -13.971 -10.949 1   21.194 ? 321  PHE B N   1 
ATOM   6634 C  CA  . PHE B 1 329 ? -17.107 -13.439 -12.251 1   21.338 ? 321  PHE B CA  1 
ATOM   6635 C  C   . PHE B 1 329 ? -18.107 -13.95  -13.291 1   24.285 ? 321  PHE B C   1 
ATOM   6636 O  O   . PHE B 1 329 ? -18.98  -14.761 -12.997 1   22.286 ? 321  PHE B O   1 
ATOM   6637 C  CB  . PHE B 1 329 ? -15.649 -13.735 -12.624 1   23.251 ? 321  PHE B CB  1 
ATOM   6638 C  CG  . PHE B 1 329 ? -15.361 -15.205 -12.902 1   25.089 ? 321  PHE B CG  1 
ATOM   6639 C  CD1 . PHE B 1 329 ? -15.119 -16.095 -11.855 1   23.963 ? 321  PHE B CD1 1 
ATOM   6640 C  CD2 . PHE B 1 329 ? -15.315 -15.705 -14.223 1   25.17  ? 321  PHE B CD2 1 
ATOM   6641 C  CE1 . PHE B 1 329 ? -14.817 -17.434 -12.073 1   26.703 ? 321  PHE B CE1 1 
ATOM   6642 C  CE2 . PHE B 1 329 ? -15.022 -17.055 -14.438 1   22.862 ? 321  PHE B CE2 1 
ATOM   6643 C  CZ  . PHE B 1 329 ? -14.778 -17.923 -13.376 1   24.486 ? 321  PHE B CZ  1 
ATOM   6644 N  N   . GLU B 1 330 ? -17.97  -13.475 -14.529 1   22.35  ? 322  GLU B N   1 
ATOM   6645 C  CA  . GLU B 1 330 ? -18.792 -13.976 -15.614 1   21.262 ? 322  GLU B CA  1 
ATOM   6646 C  C   . GLU B 1 330 ? -17.896 -14.742 -16.578 1   22.085 ? 322  GLU B C   1 
ATOM   6647 O  O   . GLU B 1 330 ? -16.857 -14.222 -16.988 1   25.496 ? 322  GLU B O   1 
ATOM   6648 C  CB  . GLU B 1 330 ? -19.444 -12.785 -16.32  1   22.362 ? 322  GLU B CB  1 
ATOM   6649 C  CG  . GLU B 1 330 ? -20.618 -12.244 -15.509 1   20.757 ? 322  GLU B CG  1 
ATOM   6650 C  CD  . GLU B 1 330 ? -20.956 -10.808 -15.887 1   25.38  ? 322  GLU B CD  1 
ATOM   6651 O  OE1 . GLU B 1 330 ? -21.234 -10.562 -17.106 1   25.583 ? 322  GLU B OE1 1 
ATOM   6652 O  OE2 . GLU B 1 330 ? -20.989 -9.9    -15.015 1   23.746 ? 322  GLU B OE2 1 
ATOM   6653 N  N   . ASP B 1 331 ? -18.353 -15.926 -16.973 1   24.944 ? 323  ASP B N   1 
ATOM   6654 C  CA  . ASP B 1 331 ? -17.582 -16.762 -17.892 1   27.521 ? 323  ASP B CA  1 
ATOM   6655 C  C   . ASP B 1 331 ? -17.757 -16.258 -19.333 1   28.891 ? 323  ASP B C   1 
ATOM   6656 O  O   . ASP B 1 331 ? -18.425 -15.245 -19.581 1   25.788 ? 323  ASP B O   1 
ATOM   6657 C  CB  . ASP B 1 331 ? -17.866 -18.245 -17.672 1   30.04  ? 323  ASP B CB  1 
ATOM   6658 C  CG  . ASP B 1 331 ? -19.229 -18.736 -18.137 1   29.249 ? 323  ASP B CG  1 
ATOM   6659 O  OD1 . ASP B 1 331 ? -19.949 -17.986 -18.831 1   30.629 ? 323  ASP B OD1 1 
ATOM   6660 O  OD2 . ASP B 1 331 ? -19.598 -19.837 -17.708 1   31.66  ? 323  ASP B OD2 1 
ATOM   6661 N  N   . GLU B 1 332 ? -17.171 -17.007 -20.286 1   33.901 ? 324  GLU B N   1 
ATOM   6662 C  CA  . GLU B 1 332 ? -17.194 -16.687 -21.715 1   42.325 ? 324  GLU B CA  1 
ATOM   6663 C  C   . GLU B 1 332 ? -18.614 -16.614 -22.288 1   39.26  ? 324  GLU B C   1 
ATOM   6664 O  O   . GLU B 1 332 ? -18.825 -15.913 -23.284 1   37.565 ? 324  GLU B O   1 
ATOM   6665 C  CB  . GLU B 1 332 ? -16.386 -17.649 -22.59  1   48.44  ? 324  GLU B CB  1 
ATOM   6666 C  CG  . GLU B 1 332 ? -14.894 -17.707 -22.263 1   66.024 ? 324  GLU B CG  1 
ATOM   6667 C  CD  . GLU B 1 332 ? -14.416 -18.536 -21.069 1   83.024 ? 324  GLU B CD  1 
ATOM   6668 O  OE1 . GLU B 1 332 ? -15.199 -19.092 -20.236 1   77.099 ? 324  GLU B OE1 1 
ATOM   6669 O  OE2 . GLU B 1 332 ? -13.163 -18.641 -20.995 1   89.56  ? 324  GLU B OE2 1 
ATOM   6670 N  N   . GLN B 1 333 ? -19.583 -17.309 -21.656 1   32.213 ? 325  GLN B N   1 
ATOM   6671 C  CA  . GLN B 1 333 ? -20.972 -17.339 -22.086 1   32.35  ? 325  GLN B CA  1 
ATOM   6672 C  C   . GLN B 1 333 ? -21.866 -16.398 -21.274 1   33.159 ? 325  GLN B C   1 
ATOM   6673 O  O   . GLN B 1 333 ? -23.086 -16.451 -21.42  1   30.357 ? 325  GLN B O   1 
ATOM   6674 C  CB  . GLN B 1 333 ? -21.483 -18.769 -21.929 1   42.675 ? 325  GLN B CB  1 
ATOM   6675 C  CG  . GLN B 1 333 ? -20.921 -19.778 -22.926 1   46.52  ? 325  GLN B CG  1 
ATOM   6676 C  CD  . GLN B 1 333 ? -21.308 -21.193 -22.547 1   57.708 ? 325  GLN B CD  1 
ATOM   6677 O  OE1 . GLN B 1 333 ? -22.482 -21.579 -22.545 1   61.182 ? 325  GLN B OE1 1 
ATOM   6678 N  NE2 . GLN B 1 333 ? -20.325 -21.971 -22.121 1   66.383 ? 325  GLN B NE2 1 
ATOM   6679 N  N   . GLY B 1 334 ? -21.258 -15.544 -20.418 1   27.665 ? 326  GLY B N   1 
ATOM   6680 C  CA  . GLY B 1 334 ? -21.985 -14.564 -19.626 1   27.432 ? 326  GLY B CA  1 
ATOM   6681 C  C   . GLY B 1 334 ? -22.585 -15.163 -18.341 1   23.121 ? 326  GLY B C   1 
ATOM   6682 O  O   . GLY B 1 334 ? -23.358 -14.459 -17.691 1   27.248 ? 326  GLY B O   1 
ATOM   6683 N  N   . ARG B 1 335 ? -22.243 -16.415 -18.016 1   24.564 ? 327  ARG B N   1 
ATOM   6684 C  CA  . ARG B 1 335 ? -22.804 -17.054 -16.833 1   24.504 ? 327  ARG B CA  1 
ATOM   6685 C  C   . ARG B 1 335 ? -22.064 -16.517 -15.608 1   22.743 ? 327  ARG B C   1 
ATOM   6686 O  O   . ARG B 1 335 ? -20.849 -16.323 -15.638 1   24.436 ? 327  ARG B O   1 
ATOM   6687 C  CB  . ARG B 1 335 ? -22.638 -18.582 -16.875 1   26.341 ? 327  ARG B CB  1 
ATOM   6688 C  CG  . ARG B 1 335 ? -23.367 -19.138 -18.102 1   26.607 ? 327  ARG B CG  1 
ATOM   6689 C  CD  . ARG B 1 335 ? -23.436 -20.64  -18.107 1   26.856 ? 327  ARG B CD  1 
ATOM   6690 N  NE  . ARG B 1 335 ? -22.087 -21.17  -18.259 1   32.685 ? 327  ARG B NE  1 
ATOM   6691 C  CZ  . ARG B 1 335 ? -21.808 -22.366 -18.767 1   44.431 ? 327  ARG B CZ  1 
ATOM   6692 N  NH1 . ARG B 1 335 ? -22.802 -23.201 -19.034 1   42.951 ? 327  ARG B NH1 1 
ATOM   6693 N  NH2 . ARG B 1 335 ? -20.544 -22.704 -18.984 1   39.758 ? 327  ARG B NH2 1 
ATOM   6694 N  N   . ILE B 1 336 ? -22.841 -16.296 -14.538 1   21.835 ? 328  ILE B N   1 
ATOM   6695 C  CA  . ILE B 1 336 ? -22.298 -15.83  -13.261 1   20.22  ? 328  ILE B CA  1 
ATOM   6696 C  C   . ILE B 1 336 ? -21.772 -17.055 -12.514 1   19.497 ? 328  ILE B C   1 
ATOM   6697 O  O   . ILE B 1 336 ? -22.508 -18.014 -12.265 1   22.135 ? 328  ILE B O   1 
ATOM   6698 C  CB  . ILE B 1 336 ? -23.445 -15.144 -12.515 1   18.431 ? 328  ILE B CB  1 
ATOM   6699 C  CG1 . ILE B 1 336 ? -23.941 -13.864 -13.203 1   21.01  ? 328  ILE B CG1 1 
ATOM   6700 C  CG2 . ILE B 1 336 ? -23.049 -14.897 -11.04  1   20     ? 328  ILE B CG2 1 
ATOM   6701 C  CD1 . ILE B 1 336 ? -25.327 -13.456 -12.762 1   23.687 ? 328  ILE B CD1 1 
ATOM   6702 N  N   . ILE B 1 337 ? -20.485 -16.999 -12.174 1   19.824 ? 329  ILE B N   1 
ATOM   6703 C  CA  . ILE B 1 337 ? -19.803 -18.058 -11.442 1   20.924 ? 329  ILE B CA  1 
ATOM   6704 C  C   . ILE B 1 337 ? -19.421 -17.467 -10.086 1   21.537 ? 329  ILE B C   1 
ATOM   6705 O  O   . ILE B 1 337 ? -18.772 -16.422 -10.041 1   21.853 ? 329  ILE B O   1 
ATOM   6706 C  CB  . ILE B 1 337 ? -18.527 -18.523 -12.194 1   22.306 ? 329  ILE B CB  1 
ATOM   6707 C  CG1 . ILE B 1 337 ? -18.801 -18.855 -13.701 1   23.806 ? 329  ILE B CG1 1 
ATOM   6708 C  CG2 . ILE B 1 337 ? -17.827 -19.693 -11.466 1   21.514 ? 329  ILE B CG2 1 
ATOM   6709 C  CD1 . ILE B 1 337 ? -19.873 -19.929 -13.908 1   23.269 ? 329  ILE B CD1 1 
ATOM   6710 N  N   . ILE B 1 338 ? -19.822 -18.161 -9.013  1   21.324 ? 330  ILE B N   1 
ATOM   6711 C  CA  . ILE B 1 338 ? -19.555 -17.688 -7.654  1   20.717 ? 330  ILE B CA  1 
ATOM   6712 C  C   . ILE B 1 338 ? -19.029 -18.889 -6.866  1   20.362 ? 330  ILE B C   1 
ATOM   6713 O  O   . ILE B 1 338 ? -19.653 -19.958 -6.865  1   20.65  ? 330  ILE B O   1 
ATOM   6714 C  CB  . ILE B 1 338 ? -20.843 -17.133 -7.019  1   19.917 ? 330  ILE B CB  1 
ATOM   6715 C  CG1 . ILE B 1 338 ? -21.389 -15.947 -7.796  1   19.362 ? 330  ILE B CG1 1 
ATOM   6716 C  CG2 . ILE B 1 338 ? -20.62  -16.756 -5.541  1   20.199 ? 330  ILE B CG2 1 
ATOM   6717 C  CD1 . ILE B 1 338 ? -22.802 -15.517 -7.433  1   19.701 ? 330  ILE B CD1 1 
ATOM   6718 N  N   . ASP B 1 339 ? -17.928 -18.699 -6.117  1   18.806 ? 331  ASP B N   1 
ATOM   6719 C  CA  . ASP B 1 339 ? -17.549 -19.738 -5.157  1   18.436 ? 331  ASP B CA  1 
ATOM   6720 C  C   . ASP B 1 339 ? -17.933 -19.283 -3.749  1   17.377 ? 331  ASP B C   1 
ATOM   6721 O  O   . ASP B 1 339 ? -17.835 -18.086 -3.44   1   19.809 ? 331  ASP B O   1 
ATOM   6722 C  CB  . ASP B 1 339 ? -16.065 -20.063 -5.209  1   18.686 ? 331  ASP B CB  1 
ATOM   6723 C  CG  . ASP B 1 339 ? -15.573 -20.827 -6.44   1   20.879 ? 331  ASP B CG  1 
ATOM   6724 O  OD1 . ASP B 1 339 ? -16.353 -20.887 -7.422  1   21.982 ? 331  ASP B OD1 1 
ATOM   6725 O  OD2 . ASP B 1 339 ? -14.421 -21.285 -6.421  1   20.774 ? 331  ASP B OD2 1 
ATOM   6726 N  N   . SER B 1 340 ? -18.339 -20.25  -2.92   1   19.565 ? 332  SER B N   1 
ATOM   6727 C  CA  . SER B 1 340 ? -18.708 -19.894 -1.552  1   18.601 ? 332  SER B CA  1 
ATOM   6728 C  C   . SER B 1 340 ? -18.512 -21.071 -0.628  1   20.331 ? 332  SER B C   1 
ATOM   6729 O  O   . SER B 1 340 ? -18.445 -22.209 -1.084  1   20.367 ? 332  SER B O   1 
ATOM   6730 C  CB  . SER B 1 340 ? -20.156 -19.442 -1.489  1   18.46  ? 332  SER B CB  1 
ATOM   6731 O  OG  . SER B 1 340 ? -21.073 -20.547 -1.531  1   20.119 ? 332  SER B OG  1 
ATOM   6732 N  N   . SER B 1 341 ? -18.471 -20.79  0.691   1   18.962 ? 333  SER B N   1 
ATOM   6733 C  CA  . SER B 1 341 ? -18.705 -21.918 1.593   1   19.539 ? 333  SER B CA  1 
ATOM   6734 C  C   . SER B 1 341 ? -20.139 -22.442 1.429   1   18.306 ? 333  SER B C   1 
ATOM   6735 O  O   . SER B 1 341 ? -21.028 -21.723 0.972   1   18.765 ? 333  SER B O   1 
ATOM   6736 C  CB  . SER B 1 341 ? -18.448 -21.533 3.056   1   19.07  ? 333  SER B CB  1 
ATOM   6737 O  OG  . SER B 1 341 ? -19.294 -20.456 3.445   1   18.749 ? 333  SER B OG  1 
ATOM   6738 N  N   . LEU B 1 342 ? -20.359 -23.706 1.838   1   18.898 ? 334  LEU B N   1 
ATOM   6739 C  CA  . LEU B 1 342 ? -21.713 -24.234 1.919   1   18.423 ? 334  LEU B CA  1 
ATOM   6740 C  C   . LEU B 1 342 ? -21.79  -25.186 3.108   1   19.904 ? 334  LEU B C   1 
ATOM   6741 O  O   . LEU B 1 342 ? -21.144 -26.242 3.098   1   20.588 ? 334  LEU B O   1 
ATOM   6742 C  CB  . LEU B 1 342 ? -22.133 -24.985 0.64    1   19.656 ? 334  LEU B CB  1 
ATOM   6743 C  CG  . LEU B 1 342 ? -23.547 -25.598 0.677   1   18.938 ? 334  LEU B CG  1 
ATOM   6744 C  CD1 . LEU B 1 342 ? -24.69  -24.607 0.975   1   19.003 ? 334  LEU B CD1 1 
ATOM   6745 C  CD2 . LEU B 1 342 ? -23.867 -26.333 -0.663  1   22.068 ? 334  LEU B CD2 1 
ATOM   6746 N  N   . VAL B 1 343 ? -22.638 -24.814 4.061   1   19.227 ? 335  VAL B N   1 
ATOM   6747 C  CA  . VAL B 1 343 ? -22.961 -25.692 5.19    1   19.058 ? 335  VAL B CA  1 
ATOM   6748 C  C   . VAL B 1 343 ? -24.356 -26.238 4.91    1   20.51  ? 335  VAL B C   1 
ATOM   6749 O  O   . VAL B 1 343 ? -25.293 -25.472 4.669   1   20.201 ? 335  VAL B O   1 
ATOM   6750 C  CB  . VAL B 1 343 ? -22.852 -24.95  6.537   1   19.988 ? 335  VAL B CB  1 
ATOM   6751 C  CG1 . VAL B 1 343 ? -23.297 -25.827 7.717   1   19.434 ? 335  VAL B CG1 1 
ATOM   6752 C  CG2 . VAL B 1 343 ? -21.42  -24.481 6.766   1   23.537 ? 335  VAL B CG2 1 
ATOM   6753 N  N   . HIS B 1 344 ? -24.48  -27.585 4.996   1   18.572 ? 336  HIS B N   1 
ATOM   6754 C  CA  . HIS B 1 344 ? -25.711 -28.258 4.585   1   22.312 ? 336  HIS B CA  1 
ATOM   6755 C  C   . HIS B 1 344 ? -26.688 -28.33  5.76    1   22.352 ? 336  HIS B C   1 
ATOM   6756 O  O   . HIS B 1 344 ? -27.08  -29.427 6.194   1   22.297 ? 336  HIS B O   1 
ATOM   6757 C  CB  . HIS B 1 344 ? -25.4   -29.644 3.998   1   22.745 ? 336  HIS B CB  1 
ATOM   6758 C  CG  . HIS B 1 344 ? -24.696 -29.595 2.686   1   21.995 ? 336  HIS B CG  1 
ATOM   6759 N  ND1 . HIS B 1 344 ? -23.339 -29.413 2.496   1   25.166 ? 336  HIS B ND1 1 
ATOM   6760 C  CD2 . HIS B 1 344 ? -25.232 -29.717 1.461   1   24.346 ? 336  HIS B CD2 1 
ATOM   6761 C  CE1 . HIS B 1 344 ? -23.08  -29.403 1.194   1   23.962 ? 336  HIS B CE1 1 
ATOM   6762 N  NE2 . HIS B 1 344 ? -24.217 -29.569 0.554   1   28.329 ? 336  HIS B NE2 1 
ATOM   6763 N  N   . GLY B 1 345 ? -27.02  -27.151 6.325   1   20.019 ? 337  GLY B N   1 
ATOM   6764 C  CA  . GLY B 1 345 ? -27.831 -26.997 7.519   1   20.648 ? 337  GLY B CA  1 
ATOM   6765 C  C   . GLY B 1 345 ? -27.54  -25.662 8.206   1   23.788 ? 337  GLY B C   1 
ATOM   6766 O  O   . GLY B 1 345 ? -26.907 -24.798 7.599   1   21.076 ? 337  GLY B O   1 
ATOM   6767 N  N   . ASN B 1 346 ? -27.932 -25.547 9.479   1   20.861 ? 338  ASN B N   1 
ATOM   6768 C  CA  . ASN B 1 346 ? -27.839 -24.269 10.182  1   21.784 ? 338  ASN B CA  1 
ATOM   6769 C  C   . ASN B 1 346 ? -26.467 -24.109 10.854  1   21.114 ? 338  ASN B C   1 
ATOM   6770 O  O   . ASN B 1 346 ? -26.193 -24.754 11.865  1   21.112 ? 338  ASN B O   1 
ATOM   6771 C  CB  . ASN B 1 346 ? -29.007 -24.132 11.153  1   20.679 ? 338  ASN B CB  1 
ATOM   6772 C  CG  . ASN B 1 346 ? -29.085 -22.746 11.766  1   22.609 ? 338  ASN B CG  1 
ATOM   6773 O  OD1 . ASN B 1 346 ? -28.286 -21.876 11.386  1   21.059 ? 338  ASN B OD1 1 
ATOM   6774 N  ND2 . ASN B 1 346 ? -30.008 -22.52  12.7    1   20.073 ? 338  ASN B ND2 1 
ATOM   6775 N  N   . ALA B 1 347 ? -25.639 -23.179 10.361  1   20.312 ? 339  ALA B N   1 
ATOM   6776 C  CA  . ALA B 1 347 ? -24.352 -22.848 10.981  1   19.278 ? 339  ALA B CA  1 
ATOM   6777 C  C   . ALA B 1 347 ? -24.509 -21.825 12.1    1   18.912 ? 339  ALA B C   1 
ATOM   6778 O  O   . ALA B 1 347 ? -23.502 -21.568 12.773  1   20.091 ? 339  ALA B O   1 
ATOM   6779 C  CB  . ALA B 1 347 ? -23.372 -22.362 9.918   1   20.377 ? 339  ALA B CB  1 
ATOM   6780 N  N   . PHE B 1 348 ? -25.699 -21.242 12.253  1   18.547 ? 340  PHE B N   1 
ATOM   6781 C  CA  . PHE B 1 348 ? -26.005 -20.361 13.394  1   18.865 ? 340  PHE B CA  1 
ATOM   6782 C  C   . PHE B 1 348 ? -27.099 -21.031 14.231  1   18.619 ? 340  PHE B C   1 
ATOM   6783 O  O   . PHE B 1 348 ? -28.244 -20.553 14.279  1   19.147 ? 340  PHE B O   1 
ATOM   6784 C  CB  . PHE B 1 348 ? -26.516 -18.992 12.911  1   18.436 ? 340  PHE B CB  1 
ATOM   6785 C  CG  . PHE B 1 348 ? -25.511 -17.943 12.449  1   16.53  ? 340  PHE B CG  1 
ATOM   6786 C  CD1 . PHE B 1 348 ? -24.12  -18.182 12.403  1   18.516 ? 340  PHE B CD1 1 
ATOM   6787 C  CD2 . PHE B 1 348 ? -25.992 -16.688 12.087  1   17.994 ? 340  PHE B CD2 1 
ATOM   6788 C  CE1 . PHE B 1 348 ? -23.221 -17.166 12.066  1   20.277 ? 340  PHE B CE1 1 
ATOM   6789 C  CE2 . PHE B 1 348 ? -25.099 -15.659 11.724  1   17.299 ? 340  PHE B CE2 1 
ATOM   6790 C  CZ  . PHE B 1 348 ? -23.726 -15.914 11.721  1   18.41  ? 340  PHE B CZ  1 
ATOM   6791 N  N   . PRO B 1 349 ? -26.8   -22.167 14.914  1   19.537 ? 341  PRO B N   1 
ATOM   6792 C  CA  . PRO B 1 349 ? -27.861 -22.911 15.599  1   21.103 ? 341  PRO B CA  1 
ATOM   6793 C  C   . PRO B 1 349 ? -28.528 -22.115 16.729  1   20.559 ? 341  PRO B C   1 
ATOM   6794 O  O   . PRO B 1 349 ? -29.608 -22.478 17.205  1   21.453 ? 341  PRO B O   1 
ATOM   6795 C  CB  . PRO B 1 349 ? -27.126 -24.177 16.125  1   20.819 ? 341  PRO B CB  1 
ATOM   6796 C  CG  . PRO B 1 349 ? -25.688 -23.773 16.202  1   21.253 ? 341  PRO B CG  1 
ATOM   6797 C  CD  . PRO B 1 349 ? -25.475 -22.821 15.012  1   20.304 ? 341  PRO B CD  1 
ATOM   6798 N  N   . PHE B 1 350 ? -27.856 -21.053 17.2    1   19.805 ? 342  PHE B N   1 
ATOM   6799 C  CA  . PHE B 1 350 ? -28.393 -20.148 18.212  1   18.551 ? 342  PHE B CA  1 
ATOM   6800 C  C   . PHE B 1 350 ? -29.551 -19.289 17.689  1   20.134 ? 342  PHE B C   1 
ATOM   6801 O  O   . PHE B 1 350 ? -30.22  -18.629 18.485  1   20.673 ? 342  PHE B O   1 
ATOM   6802 C  CB  . PHE B 1 350 ? -27.229 -19.326 18.79   1   19.15  ? 342  PHE B CB  1 
ATOM   6803 C  CG  . PHE B 1 350 ? -26.342 -18.634 17.747  1   16.953 ? 342  PHE B CG  1 
ATOM   6804 C  CD1 . PHE B 1 350 ? -26.699 -17.434 17.157  1   17.689 ? 342  PHE B CD1 1 
ATOM   6805 C  CD2 . PHE B 1 350 ? -25.168 -19.264 17.329  1   19.31  ? 342  PHE B CD2 1 
ATOM   6806 C  CE1 . PHE B 1 350 ? -25.866 -16.851 16.189  1   17.538 ? 342  PHE B CE1 1 
ATOM   6807 C  CE2 . PHE B 1 350 ? -24.348 -18.72  16.363  1   18.916 ? 342  PHE B CE2 1 
ATOM   6808 C  CZ  . PHE B 1 350 ? -24.691 -17.484 15.808  1   18.546 ? 342  PHE B CZ  1 
ATOM   6809 N  N   . PHE B 1 351 ? -29.843 -19.357 16.368  1   19.676 ? 343  PHE B N   1 
ATOM   6810 C  CA  . PHE B 1 351 ? -31.1   -18.806 15.86   1   18.866 ? 343  PHE B CA  1 
ATOM   6811 C  C   . PHE B 1 351 ? -31.868 -19.971 15.241  1   20.668 ? 343  PHE B C   1 
ATOM   6812 O  O   . PHE B 1 351 ? -31.897 -20.151 14.011  1   20.457 ? 343  PHE B O   1 
ATOM   6813 C  CB  . PHE B 1 351 ? -30.868 -17.708 14.812  1   18.025 ? 343  PHE B CB  1 
ATOM   6814 C  CG  . PHE B 1 351 ? -30.056 -16.487 15.265  1   17.718 ? 343  PHE B CG  1 
ATOM   6815 C  CD1 . PHE B 1 351 ? -30.124 -15.974 16.571  1   18.021 ? 343  PHE B CD1 1 
ATOM   6816 C  CD2 . PHE B 1 351 ? -29.215 -15.843 14.342  1   17.516 ? 343  PHE B CD2 1 
ATOM   6817 C  CE1 . PHE B 1 351 ? -29.386 -14.864 16.954  1   18.872 ? 343  PHE B CE1 1 
ATOM   6818 C  CE2 . PHE B 1 351 ? -28.458 -14.736 14.722  1   18.313 ? 343  PHE B CE2 1 
ATOM   6819 C  CZ  . PHE B 1 351 ? -28.556 -14.228 16.026  1   17.868 ? 343  PHE B CZ  1 
ATOM   6820 N  N   . PRO B 1 352 ? -32.485 -20.838 16.079  1   20.589 ? 344  PRO B N   1 
ATOM   6821 C  CA  . PRO B 1 352 ? -33.116 -22.047 15.55   1   22.457 ? 344  PRO B CA  1 
ATOM   6822 C  C   . PRO B 1 352 ? -34.434 -21.744 14.839  1   20.495 ? 344  PRO B C   1 
ATOM   6823 O  O   . PRO B 1 352 ? -34.943 -20.602 14.859  1   22.245 ? 344  PRO B O   1 
ATOM   6824 C  CB  . PRO B 1 352 ? -33.303 -22.862 16.874  1   20.554 ? 344  PRO B CB  1 
ATOM   6825 C  CG  . PRO B 1 352 ? -33.6   -21.788 17.902  1   23.255 ? 344  PRO B CG  1 
ATOM   6826 C  CD  . PRO B 1 352 ? -32.525 -20.755 17.56   1   21.638 ? 344  PRO B CD  1 
ATOM   6827 N  N   . PRO B 1 353 ? -35.061 -22.779 14.223  1   22.93  ? 345  PRO B N   1 
ATOM   6828 C  CA  . PRO B 1 353 ? -36.394 -22.615 13.667  1   21.819 ? 345  PRO B CA  1 
ATOM   6829 C  C   . PRO B 1 353 ? -37.457 -22.236 14.69   1   26.011 ? 345  PRO B C   1 
ATOM   6830 O  O   . PRO B 1 353 ? -37.259 -22.381 15.888  1   24.308 ? 345  PRO B O   1 
ATOM   6831 C  CB  . PRO B 1 353 ? -36.656 -24.032 13.105  1   22.621 ? 345  PRO B CB  1 
ATOM   6832 C  CG  . PRO B 1 353 ? -35.293 -24.604 12.82   1   21.364 ? 345  PRO B CG  1 
ATOM   6833 C  CD  . PRO B 1 353 ? -34.503 -24.137 14.022  1   23.925 ? 345  PRO B CD  1 
ATOM   6834 N  N   . ASP B 1 354 ? -38.584 -21.774 14.17   1   28.45  ? 346  ASP B N   1 
ATOM   6835 C  CA  . ASP B 1 354 ? -39.733 -21.312 14.93   1   32.907 ? 346  ASP B CA  1 
ATOM   6836 C  C   . ASP B 1 354 ? -40.549 -22.518 15.419  1   37.34  ? 346  ASP B C   1 
ATOM   6837 O  O   . ASP B 1 354 ? -40.818 -22.641 16.614  1   35.614 ? 346  ASP B O   1 
ATOM   6838 C  CB  . ASP B 1 354 ? -40.531 -20.358 14.047  1   40.467 ? 346  ASP B CB  1 
ATOM   6839 C  CG  . ASP B 1 354 ? -41.132 -19.161 14.755  1   50.723 ? 346  ASP B CG  1 
ATOM   6840 O  OD1 . ASP B 1 354 ? -40.384 -18.499 15.497  1   46.804 ? 346  ASP B OD1 1 
ATOM   6841 O  OD2 . ASP B 1 354 ? -42.338 -18.901 14.556  1   58.994 ? 346  ASP B OD2 1 
ATOM   6842 N  N   . SER B 1 355 ? -40.869 -23.435 14.496  1   35.455 ? 347  SER B N   1 
ATOM   6843 C  CA  . SER B 1 355 ? -41.794 -24.53  14.757  1   38.641 ? 347  SER B CA  1 
ATOM   6844 C  C   . SER B 1 355 ? -41.11  -25.647 15.534  1   38.636 ? 347  SER B C   1 
ATOM   6845 O  O   . SER B 1 355 ? -39.909 -25.895 15.417  1   36.747 ? 347  SER B O   1 
ATOM   6846 C  CB  . SER B 1 355 ? -42.401 -25.053 13.469  1   40.417 ? 347  SER B CB  1 
ATOM   6847 O  OG  . SER B 1 355 ? -41.519 -25.947 12.796  1   45.517 ? 347  SER B OG  1 
ATOM   6848 N  N   . ASP B 1 356 ? -41.929 -26.377 16.303  1   43.226 ? 348  ASP B N   1 
ATOM   6849 C  CA  . ASP B 1 356 ? -41.475 -27.52  17.074  1   44.498 ? 348  ASP B CA  1 
ATOM   6850 C  C   . ASP B 1 356 ? -40.809 -28.591 16.204  1   38.493 ? 348  ASP B C   1 
ATOM   6851 O  O   . ASP B 1 356 ? -39.728 -29.083 16.544  1   32.307 ? 348  ASP B O   1 
ATOM   6852 C  CB  . ASP B 1 356 ? -42.61  -28.083 17.915  1   58.34  ? 348  ASP B CB  1 
ATOM   6853 C  CG  . ASP B 1 356 ? -42.161 -28.547 19.291  1   68.906 ? 348  ASP B CG  1 
ATOM   6854 O  OD1 . ASP B 1 356 ? -41.198 -29.347 19.345  1   73.687 ? 348  ASP B OD1 1 
ATOM   6855 O  OD2 . ASP B 1 356 ? -42.742 -28.064 20.292  1   76.435 ? 348  ASP B OD2 1 
ATOM   6856 N  N   . GLU B 1 357 ? -41.44  -28.936 15.07   1   40.063 ? 349  GLU B N   1 
ATOM   6857 C  CA  . GLU B 1 357 ? -40.91  -29.99  14.211  1   38.957 ? 349  GLU B CA  1 
ATOM   6858 C  C   . GLU B 1 357 ? -39.537 -29.616 13.641  1   34.765 ? 349  GLU B C   1 
ATOM   6859 O  O   . GLU B 1 357 ? -38.622 -30.445 13.634  1   32.937 ? 349  GLU B O   1 
ATOM   6860 C  CB  . GLU B 1 357 ? -41.889 -30.382 13.108  1   42.345 ? 349  GLU B CB  1 
ATOM   6861 C  CG  . GLU B 1 357 ? -41.445 -31.658 12.402  1   52.42  ? 349  GLU B CG  1 
ATOM   6862 C  CD  . GLU B 1 357 ? -42.326 -32.146 11.273  1   61.487 ? 349  GLU B CD  1 
ATOM   6863 O  OE1 . GLU B 1 357 ? -42.589 -31.333 10.363  1   60.706 ? 349  GLU B OE1 1 
ATOM   6864 O  OE2 . GLU B 1 357 ? -42.712 -33.336 11.293  1   64.3   ? 349  GLU B OE2 1 
ATOM   6865 N  N   . GLN B 1 358 ? -39.4   -28.362 13.185  1   32.92  ? 350  GLN B N   1 
ATOM   6866 C  CA  . GLN B 1 358 ? -38.136 -27.939 12.589  1   31.498 ? 350  GLN B CA  1 
ATOM   6867 C  C   . GLN B 1 358 ? -37.047 -27.838 13.655  1   27.244 ? 350  GLN B C   1 
ATOM   6868 O  O   . GLN B 1 358 ? -35.895 -28.163 13.366  1   26.577 ? 350  GLN B O   1 
ATOM   6869 C  CB  . GLN B 1 358 ? -38.318 -26.642 11.804  1   28.739 ? 350  GLN B CB  1 
ATOM   6870 C  CG  . GLN B 1 358 ? -38.929 -26.8   10.413  1   29.396 ? 350  GLN B CG  1 
ATOM   6871 C  CD  . GLN B 1 358 ? -38.603 -25.612 9.53    1   33.368 ? 350  GLN B CD  1 
ATOM   6872 O  OE1 . GLN B 1 358 ? -37.506 -25.036 9.639   1   27.494 ? 350  GLN B OE1 1 
ATOM   6873 N  NE2 . GLN B 1 358 ? -39.549 -25.204 8.688   1   32.06  ? 350  GLN B NE2 1 
ATOM   6874 N  N   . LYS B 1 359 ? -37.404 -27.408 14.885  1   28.776 ? 351  LYS B N   1 
ATOM   6875 C  CA  . LYS B 1 359 ? -36.429 -27.397 15.971  1   29.547 ? 351  LYS B CA  1 
ATOM   6876 C  C   . LYS B 1 359 ? -35.907 -28.804 16.261  1   30.936 ? 351  LYS B C   1 
ATOM   6877 O  O   . LYS B 1 359 ? -34.721 -28.998 16.492  1   29.691 ? 351  LYS B O   1 
ATOM   6878 C  CB  . LYS B 1 359 ? -36.974 -26.828 17.275  1   32.509 ? 351  LYS B CB  1 
ATOM   6879 C  CG  . LYS B 1 359 ? -37.136 -25.328 17.318  1   37.801 ? 351  LYS B CG  1 
ATOM   6880 C  CD  . LYS B 1 359 ? -37.321 -24.999 18.798  1   42.619 ? 351  LYS B CD  1 
ATOM   6881 C  CE  . LYS B 1 359 ? -38.178 -23.802 18.974  1   47.756 ? 351  LYS B CE  1 
ATOM   6882 N  NZ  . LYS B 1 359 ? -38.474 -23.79  20.41   1   59.442 ? 351  LYS B NZ  1 
ATOM   6883 N  N   . LYS B 1 360 ? -36.815 -29.794 16.215  1   39.006 ? 352  LYS B N   1 
ATOM   6884 C  CA  . LYS B 1 360 ? -36.433 -31.182 16.464  1   39.47  ? 352  LYS B CA  1 
ATOM   6885 C  C   . LYS B 1 360 ? -35.559 -31.699 15.328  1   28.478 ? 352  LYS B C   1 
ATOM   6886 O  O   . LYS B 1 360 ? -34.625 -32.426 15.595  1   32.251 ? 352  LYS B O   1 
ATOM   6887 C  CB  . LYS B 1 360 ? -37.614 -32.044 16.933  1   44.832 ? 352  LYS B CB  1 
ATOM   6888 C  CG  . LYS B 1 360 ? -37.694 -31.905 18.451  1   53.428 ? 352  LYS B CG  1 
ATOM   6889 C  CD  . LYS B 1 360 ? -39     -32.145 19.193  1   66.326 ? 352  LYS B CD  1 
ATOM   6890 C  CE  . LYS B 1 360 ? -38.776 -31.604 20.578  1   63.522 ? 352  LYS B CE  1 
ATOM   6891 N  NZ  . LYS B 1 360 ? -40.043 -31.121 21.13   1   74.734 ? 352  LYS B NZ  1 
ATOM   6892 N  N   . LYS B 1 361 ? -35.788 -31.231 14.095  1   28.417 ? 353  LYS B N   1 
ATOM   6893 C  CA  . LYS B 1 361 ? -34.915 -31.569 12.979  1   29.027 ? 353  LYS B CA  1 
ATOM   6894 C  C   . LYS B 1 361 ? -33.513 -31.005 13.202  1   27.988 ? 353  LYS B C   1 
ATOM   6895 O  O   . LYS B 1 361 ? -32.54  -31.7   12.983  1   25.895 ? 353  LYS B O   1 
ATOM   6896 C  CB  . LYS B 1 361 ? -35.577 -31.169 11.658  1   25.453 ? 353  LYS B CB  1 
ATOM   6897 C  CG  . LYS B 1 361 ? -34.659 -31.415 10.469  1   26.354 ? 353  LYS B CG  1 
ATOM   6898 C  CD  . LYS B 1 361 ? -35.328 -31.102 9.136   1   28.307 ? 353  LYS B CD  1 
ATOM   6899 C  CE  . LYS B 1 361 ? -34.43  -31.295 7.951   1   31.863 ? 353  LYS B CE  1 
ATOM   6900 N  NZ  . LYS B 1 361 ? -33.893 -32.652 7.85    1   32.42  ? 353  LYS B NZ  1 
ATOM   6901 N  N   . GLN B 1 362 ? -33.396 -29.736 13.639  1   27.132 ? 354  GLN B N   1 
ATOM   6902 C  CA  . GLN B 1 362 ? -32.068 -29.166 13.833  1   26.32  ? 354  GLN B CA  1 
ATOM   6903 C  C   . GLN B 1 362 ? -31.3   -29.982 14.88   1   26.596 ? 354  GLN B C   1 
ATOM   6904 O  O   . GLN B 1 362 ? -30.126 -30.266 14.698  1   27.512 ? 354  GLN B O   1 
ATOM   6905 C  CB  . GLN B 1 362 ? -32.155 -27.675 14.189  1   24.808 ? 354  GLN B CB  1 
ATOM   6906 C  CG  . GLN B 1 362 ? -30.792 -27.081 14.553  1   25.008 ? 354  GLN B CG  1 
ATOM   6907 C  CD  . GLN B 1 362 ? -30.827 -25.589 14.82   1   24.033 ? 354  GLN B CD  1 
ATOM   6908 O  OE1 . GLN B 1 362 ? -31.331 -24.815 14.007  1   23.284 ? 354  GLN B OE1 1 
ATOM   6909 N  NE2 . GLN B 1 362 ? -30.342 -25.159 15.978  1   25.113 ? 354  GLN B NE2 1 
ATOM   6910 N  N   . GLU B 1 363 ? -32.021 -30.332 15.958  1   31.436 ? 355  GLU B N   1 
ATOM   6911 C  CA  . GLU B 1 363 ? -31.417 -31.043 17.068  1   35.253 ? 355  GLU B CA  1 
ATOM   6912 C  C   . GLU B 1 363 ? -31.082 -32.451 16.597  1   34.342 ? 355  GLU B C   1 
ATOM   6913 O  O   . GLU B 1 363 ? -29.968 -32.914 16.792  1   34.036 ? 355  GLU B O   1 
ATOM   6914 C  CB  . GLU B 1 363 ? -32.348 -31.051 18.282  1   36.437 ? 355  GLU B CB  1 
ATOM   6915 C  CG  . GLU B 1 363 ? -31.594 -31.459 19.551  1   44.889 ? 355  GLU B CG  1 
ATOM   6916 C  CD  . GLU B 1 363 ? -30.245 -30.778 19.785  1   43.456 ? 355  GLU B CD  1 
ATOM   6917 O  OE1 . GLU B 1 363 ? -30.237 -29.539 19.953  1   50.766 ? 355  GLU B OE1 1 
ATOM   6918 O  OE2 . GLU B 1 363 ? -29.2   -31.465 19.748  1   35.801 ? 355  GLU B OE2 1 
ATOM   6919 N  N   . ALA B 1 364 ? -32.029 -33.07  15.869  1   31.401 ? 356  ALA B N   1 
ATOM   6920 C  CA  . ALA B 1 364 ? -31.885 -34.461 15.441  1   30.691 ? 356  ALA B CA  1 
ATOM   6921 C  C   . ALA B 1 364 ? -30.74  -34.602 14.446  1   33.498 ? 356  ALA B C   1 
ATOM   6922 O  O   . ALA B 1 364 ? -29.999 -35.579 14.495  1   43.927 ? 356  ALA B O   1 
ATOM   6923 C  CB  . ALA B 1 364 ? -33.182 -35.002 14.858  1   33.149 ? 356  ALA B CB  1 
ATOM   6924 N  N   . ASP B 1 365 ? -30.59  -33.608 13.558  1   34.098 ? 357  ASP B N   1 
ATOM   6925 C  CA  . ASP B 1 365 ? -29.625 -33.698 12.475  1   33.492 ? 357  ASP B CA  1 
ATOM   6926 C  C   . ASP B 1 365 ? -28.191 -33.445 12.93   1   37.615 ? 357  ASP B C   1 
ATOM   6927 O  O   . ASP B 1 365 ? -27.279 -33.926 12.266  1   40.636 ? 357  ASP B O   1 
ATOM   6928 C  CB  . ASP B 1 365 ? -30.006 -32.822 11.293  1   34.033 ? 357  ASP B CB  1 
ATOM   6929 C  CG  . ASP B 1 365 ? -31.18  -33.296 10.451  1   38.612 ? 357  ASP B CG  1 
ATOM   6930 O  OD1 . ASP B 1 365 ? -31.708 -34.419 10.685  1   40.458 ? 357  ASP B OD1 1 
ATOM   6931 O  OD2 . ASP B 1 365 ? -31.583 -32.52  9.569   1   47.627 ? 357  ASP B OD2 1 
ATOM   6932 N  N   . GLY B 1 366 ? -27.985 -32.66  13.999  1   37.466 ? 358  GLY B N   1 
ATOM   6933 C  CA  . GLY B 1 366 ? -26.65  -32.355 14.506  1   36.374 ? 358  GLY B CA  1 
ATOM   6934 C  C   . GLY B 1 366 ? -25.799 -31.547 13.52   1   38.91  ? 358  GLY B C   1 
ATOM   6935 O  O   . GLY B 1 366 ? -26.34  -30.865 12.639  1   37.113 ? 358  GLY B O   1 
ATOM   6936 N  N   . THR B 1 367 ? -24.47  -31.679 13.646  1   33.505 ? 359  THR B N   1 
ATOM   6937 C  CA  . THR B 1 367 ? -23.505 -30.845 12.925  1   34.461 ? 359  THR B CA  1 
ATOM   6938 C  C   . THR B 1 367 ? -23.61  -31.083 11.416  1   29.936 ? 359  THR B C   1 
ATOM   6939 O  O   . THR B 1 367 ? -23.322 -32.19  10.971  1   29.102 ? 359  THR B O   1 
ATOM   6940 C  CB  . THR B 1 367 ? -22.068 -31.041 13.417  1   37.142 ? 359  THR B CB  1 
ATOM   6941 O  OG1 . THR B 1 367 ? -22.156 -30.568 14.761  1   41.231 ? 359  THR B OG1 1 
ATOM   6942 C  CG2 . THR B 1 367 ? -21.063 -30.162 12.678  1   39.541 ? 359  THR B CG2 1 
ATOM   6943 N  N   . PRO B 1 368 ? -23.977 -30.055 10.594  1   26.199 ? 360  PRO B N   1 
ATOM   6944 C  CA  . PRO B 1 368 ? -24.069 -30.253 9.145   1   25.218 ? 360  PRO B CA  1 
ATOM   6945 C  C   . PRO B 1 368 ? -22.732 -30.456 8.445   1   26.362 ? 360  PRO B C   1 
ATOM   6946 O  O   . PRO B 1 368 ? -21.678 -30.065 8.958   1   26.889 ? 360  PRO B O   1 
ATOM   6947 C  CB  . PRO B 1 368 ? -24.789 -29.014 8.639   1   23.415 ? 360  PRO B CB  1 
ATOM   6948 C  CG  . PRO B 1 368 ? -25.248 -28.234 9.855   1   25.332 ? 360  PRO B CG  1 
ATOM   6949 C  CD  . PRO B 1 368 ? -24.379 -28.693 11.015  1   22.139 ? 360  PRO B CD  1 
ATOM   6950 N  N   . LYS B 1 369 ? -22.772 -31.148 7.293   1   23.896 ? 361  LYS B N   1 
ATOM   6951 C  CA  . LYS B 1 369 ? -21.661 -31.244 6.348   1   24.682 ? 361  LYS B CA  1 
ATOM   6952 C  C   . LYS B 1 369 ? -21.28  -29.842 5.875   1   23.368 ? 361  LYS B C   1 
ATOM   6953 O  O   . LYS B 1 369 ? -22.163 -29.008 5.7     1   24.261 ? 361  LYS B O   1 
ATOM   6954 C  CB  . LYS B 1 369 ? -22.102 -32.11  5.153   1   30.319 ? 361  LYS B CB  1 
ATOM   6955 C  CG  . LYS B 1 369 ? -21.085 -32.511 4.079   1   38.025 ? 361  LYS B CG  1 
ATOM   6956 C  CD  . LYS B 1 369 ? -21.612 -33.467 2.989   1   39.321 ? 361  LYS B CD  1 
ATOM   6957 C  CE  . LYS B 1 369 ? -22.646 -32.886 2.035   1   48.184 ? 361  LYS B CE  1 
ATOM   6958 N  NZ  . LYS B 1 369 ? -23.249 -33.759 1.014   1   48.995 ? 361  LYS B NZ  1 
ATOM   6959 N  N   . ALA B 1 370 ? -19.978 -29.616 5.693   1   23.198 ? 362  ALA B N   1 
ATOM   6960 C  CA  . ALA B 1 370 ? -19.504 -28.302 5.295   1   21.196 ? 362  ALA B CA  1 
ATOM   6961 C  C   . ALA B 1 370 ? -18.427 -28.438 4.229   1   21.906 ? 362  ALA B C   1 
ATOM   6962 O  O   . ALA B 1 370 ? -17.502 -29.256 4.364   1   22.082 ? 362  ALA B O   1 
ATOM   6963 C  CB  . ALA B 1 370 ? -18.991 -27.579 6.543   1   23.366 ? 362  ALA B CB  1 
ATOM   6964 N  N   . GLN B 1 371 ? -18.598 -27.636 3.153   1   22.363 ? 363  GLN B N   1 
ATOM   6965 C  CA  . GLN B 1 371 ? -17.751 -27.727 1.962   1   21.378 ? 363  GLN B CA  1 
ATOM   6966 C  C   . GLN B 1 371 ? -17.481 -26.33  1.389   1   20.894 ? 363  GLN B C   1 
ATOM   6967 O  O   . GLN B 1 371 ? -18.013 -25.342 1.908   1   22.032 ? 363  GLN B O   1 
ATOM   6968 C  CB  . GLN B 1 371 ? -18.477 -28.56  0.89    1   23.023 ? 363  GLN B CB  1 
ATOM   6969 C  CG  . GLN B 1 371 ? -18.811 -29.993 1.319   1   24.455 ? 363  GLN B CG  1 
ATOM   6970 C  CD  . GLN B 1 371 ? -19.651 -30.732 0.29    1   22.147 ? 363  GLN B CD  1 
ATOM   6971 O  OE1 . GLN B 1 371 ? -20.683 -30.25  -0.183  1   25.017 ? 363  GLN B OE1 1 
ATOM   6972 N  NE2 . GLN B 1 371 ? -19.224 -31.952 -0.007  1   25.661 ? 363  GLN B NE2 1 
ATOM   6973 N  N   . PHE B 1 372 ? -16.611 -26.255 0.362   1   21.978 ? 364  PHE B N   1 
ATOM   6974 C  CA  . PHE B 1 372 ? -16.438 -25.072 -0.48   1   20.634 ? 364  PHE B CA  1 
ATOM   6975 C  C   . PHE B 1 372 ? -16.895 -25.443 -1.894  1   20.124 ? 364  PHE B C   1 
ATOM   6976 O  O   . PHE B 1 372 ? -16.453 -26.48  -2.42   1   23.551 ? 364  PHE B O   1 
ATOM   6977 C  CB  . PHE B 1 372 ? -14.968 -24.668 -0.431  1   21.461 ? 364  PHE B CB  1 
ATOM   6978 C  CG  . PHE B 1 372 ? -14.624 -23.366 -1.146  1   20.159 ? 364  PHE B CG  1 
ATOM   6979 C  CD1 . PHE B 1 372 ? -14.966 -22.144 -0.564  1   21.478 ? 364  PHE B CD1 1 
ATOM   6980 C  CD2 . PHE B 1 372 ? -13.887 -23.369 -2.331  1   21.122 ? 364  PHE B CD2 1 
ATOM   6981 C  CE1 . PHE B 1 372 ? -14.633 -20.943 -1.207  1   20.608 ? 364  PHE B CE1 1 
ATOM   6982 C  CE2 . PHE B 1 372 ? -13.571 -22.16  -2.982  1   23.547 ? 364  PHE B CE2 1 
ATOM   6983 C  CZ  . PHE B 1 372 ? -13.941 -20.949 -2.41   1   22.933 ? 364  PHE B CZ  1 
ATOM   6984 N  N   . VAL B 1 373 ? -17.769 -24.607 -2.463  1   20.638 ? 365  VAL B N   1 
ATOM   6985 C  CA  . VAL B 1 373 ? -18.475 -25.007 -3.679  1   21.591 ? 365  VAL B CA  1 
ATOM   6986 C  C   . VAL B 1 373 ? -18.482 -23.884 -4.712  1   22.526 ? 365  VAL B C   1 
ATOM   6987 O  O   . VAL B 1 373 ? -18.225 -22.71  -4.415  1   21.003 ? 365  VAL B O   1 
ATOM   6988 C  CB  . VAL B 1 373 ? -19.908 -25.489 -3.339  1   19.786 ? 365  VAL B CB  1 
ATOM   6989 C  CG1 . VAL B 1 373 ? -19.891 -26.64  -2.311  1   20.616 ? 365  VAL B CG1 1 
ATOM   6990 C  CG2 . VAL B 1 373 ? -20.864 -24.354 -2.933  1   18.309 ? 365  VAL B CG2 1 
ATOM   6991 N  N   . ARG B 1 374 ? -18.932 -24.257 -5.933  1   21.337 ? 366  ARG B N   1 
ATOM   6992 C  CA  . ARG B 1 374 ? -19.014 -23.343 -7.071  1   21.987 ? 366  ARG B CA  1 
ATOM   6993 C  C   . ARG B 1 374 ? -20.422 -23.365 -7.639  1   22.425 ? 366  ARG B C   1 
ATOM   6994 O  O   . ARG B 1 374 ? -20.911 -24.433 -8.029  1   23.138 ? 366  ARG B O   1 
ATOM   6995 C  CB  . ARG B 1 374 ? -17.988 -23.731 -8.135  1   23.279 ? 366  ARG B CB  1 
ATOM   6996 C  CG  . ARG B 1 374 ? -18.058 -22.865 -9.39   1   21.553 ? 366  ARG B CG  1 
ATOM   6997 C  CD  . ARG B 1 374 ? -16.814 -22.946 -10.249 1   22.69  ? 366  ARG B CD  1 
ATOM   6998 N  NE  . ARG B 1 374 ? -15.609 -22.613 -9.468  1   21.14  ? 366  ARG B NE  1 
ATOM   6999 C  CZ  . ARG B 1 374 ? -14.452 -23.254 -9.474  1   23.877 ? 366  ARG B CZ  1 
ATOM   7000 N  NH1 . ARG B 1 374 ? -14.139 -24.138 -10.445 1   25.84  ? 366  ARG B NH1 1 
ATOM   7001 N  NH2 . ARG B 1 374 ? -13.54  -23.007 -8.534  1   23.697 ? 366  ARG B NH2 1 
ATOM   7002 N  N   . TRP B 1 375 ? -21.025 -22.187 -7.715  1   19.261 ? 367  TRP B N   1 
ATOM   7003 C  CA  . TRP B 1 375 ? -22.368 -21.944 -8.228  1   19.121 ? 367  TRP B CA  1 
ATOM   7004 C  C   . TRP B 1 375 ? -22.283 -21.436 -9.668  1   23.235 ? 367  TRP B C   1 
ATOM   7005 O  O   . TRP B 1 375 ? -21.401 -20.639 -9.992  1   20.071 ? 367  TRP B O   1 
ATOM   7006 C  CB  . TRP B 1 375 ? -23.117 -20.885 -7.407  1   18.748 ? 367  TRP B CB  1 
ATOM   7007 C  CG  . TRP B 1 375 ? -23.177 -21.202 -5.934  1   20.269 ? 367  TRP B CG  1 
ATOM   7008 C  CD1 . TRP B 1 375 ? -22.258 -20.825 -4.979  1   19.913 ? 367  TRP B CD1 1 
ATOM   7009 C  CD2 . TRP B 1 375 ? -24.187 -21.988 -5.259  1   21.375 ? 367  TRP B CD2 1 
ATOM   7010 N  NE1 . TRP B 1 375 ? -22.671 -21.306 -3.762  1   19.999 ? 367  TRP B NE1 1 
ATOM   7011 C  CE2 . TRP B 1 375 ? -23.828 -22.03  -3.894  1   20.997 ? 367  TRP B CE2 1 
ATOM   7012 C  CE3 . TRP B 1 375 ? -25.346 -22.645 -5.684  1   20.791 ? 367  TRP B CE3 1 
ATOM   7013 C  CZ2 . TRP B 1 375 ? -24.584 -22.719 -2.942  1   22.111 ? 367  TRP B CZ2 1 
ATOM   7014 C  CZ3 . TRP B 1 375 ? -26.099 -23.333 -4.756  1   20.966 ? 367  TRP B CZ3 1 
ATOM   7015 C  CH2 . TRP B 1 375 ? -25.725 -23.366 -3.4    1   21.595 ? 367  TRP B CH2 1 
ATOM   7016 N  N   . THR B 1 376 ? -23.256 -21.84  -10.517 1   22.663 ? 368  THR B N   1 
ATOM   7017 C  CA  . THR B 1 376 ? -23.388 -21.29  -11.869 1   22.832 ? 368  THR B CA  1 
ATOM   7018 C  C   . THR B 1 376 ? -24.812 -20.762 -12.022 1   23.049 ? 368  THR B C   1 
ATOM   7019 O  O   . THR B 1 376 ? -25.789 -21.526 -11.907 1   23.736 ? 368  THR B O   1 
ATOM   7020 C  CB  . THR B 1 376 ? -23.096 -22.392 -12.903 1   22.766 ? 368  THR B CB  1 
ATOM   7021 O  OG1 . THR B 1 376 ? -21.766 -22.861 -12.757 1   24.361 ? 368  THR B OG1 1 
ATOM   7022 C  CG2 . THR B 1 376 ? -23.254 -21.895 -14.328 1   22.13  ? 368  THR B CG2 1 
ATOM   7023 N  N   . ILE B 1 377 ? -24.926 -19.447 -12.247 1   22.623 ? 369  ILE B N   1 
ATOM   7024 C  CA  . ILE B 1 377 ? -26.198 -18.786 -12.484 1   22.29  ? 369  ILE B CA  1 
ATOM   7025 C  C   . ILE B 1 377 ? -26.148 -18.253 -13.912 1   24.794 ? 369  ILE B C   1 
ATOM   7026 O  O   . ILE B 1 377 ? -25.499 -17.255 -14.175 1   22.63  ? 369  ILE B O   1 
ATOM   7027 C  CB  . ILE B 1 377 ? -26.461 -17.65  -11.485 1   22.916 ? 369  ILE B CB  1 
ATOM   7028 C  CG1 . ILE B 1 377 ? -26.416 -18.16  -10.028 1   22.328 ? 369  ILE B CG1 1 
ATOM   7029 C  CG2 . ILE B 1 377 ? -27.774 -16.967 -11.838 1   21.665 ? 369  ILE B CG2 1 
ATOM   7030 C  CD1 . ILE B 1 377 ? -26.474 -17.007 -9.022  1   23.201 ? 369  ILE B CD1 1 
ATOM   7031 N  N   . ASP B 1 378 ? -26.858 -18.944 -14.819 1   26.352 ? 370  ASP B N   1 
ATOM   7032 C  CA  . ASP B 1 378 ? -26.868 -18.577 -16.228 1   26.791 ? 370  ASP B CA  1 
ATOM   7033 C  C   . ASP B 1 378 ? -28.027 -17.622 -16.496 1   26.147 ? 370  ASP B C   1 
ATOM   7034 O  O   . ASP B 1 378 ? -29.183 -18.053 -16.496 1   26.66  ? 370  ASP B O   1 
ATOM   7035 C  CB  . ASP B 1 378 ? -26.924 -19.85  -17.074 1   24.149 ? 370  ASP B CB  1 
ATOM   7036 C  CG  . ASP B 1 378 ? -26.841 -19.608 -18.579 1   27.793 ? 370  ASP B CG  1 
ATOM   7037 O  OD1 . ASP B 1 378 ? -26.923 -18.439 -18.993 1   26.921 ? 370  ASP B OD1 1 
ATOM   7038 O  OD2 . ASP B 1 378 ? -26.572 -20.594 -19.292 1   28.909 ? 370  ASP B OD2 1 
ATOM   7039 N  N   . PRO B 1 379 ? -27.787 -16.303 -16.718 1   26.444 ? 371  PRO B N   1 
ATOM   7040 C  CA  . PRO B 1 379 ? -28.86  -15.331 -16.948 1   27.568 ? 371  PRO B CA  1 
ATOM   7041 C  C   . PRO B 1 379 ? -29.742 -15.547 -18.179 1   26.634 ? 371  PRO B C   1 
ATOM   7042 O  O   . PRO B 1 379 ? -30.773 -14.907 -18.287 1   26.728 ? 371  PRO B O   1 
ATOM   7043 C  CB  . PRO B 1 379 ? -28.142 -13.972 -17.07  1   28.061 ? 371  PRO B CB  1 
ATOM   7044 C  CG  . PRO B 1 379 ? -26.817 -14.209 -16.412 1   30.768 ? 371  PRO B CG  1 
ATOM   7045 C  CD  . PRO B 1 379 ? -26.472 -15.646 -16.73  1   25.808 ? 371  PRO B CD  1 
ATOM   7046 N  N   . ARG B 1 380 ? -29.314 -16.441 -19.067 1   28.487 ? 372  ARG B N   1 
ATOM   7047 C  CA  . ARG B 1 380 ? -30.094 -16.788 -20.253 1   30.515 ? 372  ARG B CA  1 
ATOM   7048 C  C   . ARG B 1 380 ? -31.215 -17.753 -19.883 1   35.202 ? 372  ARG B C   1 
ATOM   7049 O  O   . ARG B 1 380 ? -32.179 -17.871 -20.636 1   34.477 ? 372  ARG B O   1 
ATOM   7050 C  CB  . ARG B 1 380 ? -29.189 -17.459 -21.285 1   29.318 ? 372  ARG B CB  1 
ATOM   7051 C  CG  . ARG B 1 380 ? -28.148 -16.509 -21.853 1   29.717 ? 372  ARG B CG  1 
ATOM   7052 C  CD  . ARG B 1 380 ? -27.071 -17.255 -22.587 1   28.821 ? 372  ARG B CD  1 
ATOM   7053 N  NE  . ARG B 1 380 ? -26.414 -18.387 -21.914 1   31.538 ? 372  ARG B NE  1 
ATOM   7054 C  CZ  . ARG B 1 380 ? -25.507 -19.193 -22.417 1   32.782 ? 372  ARG B CZ  1 
ATOM   7055 N  NH1 . ARG B 1 380 ? -25.132 -19.054 -23.696 1   37.833 ? 372  ARG B NH1 1 
ATOM   7056 N  NH2 . ARG B 1 380 ? -24.958 -20.148 -21.663 1   31.286 ? 372  ARG B NH2 1 
ATOM   7057 N  N   . LYS B 1 381 ? -31.086 -18.438 -18.736 1   31.914 ? 373  LYS B N   1 
ATOM   7058 C  CA  . LYS B 1 381 ? -32.06  -19.426 -18.309 1   31.696 ? 373  LYS B CA  1 
ATOM   7059 C  C   . LYS B 1 381 ? -33.271 -18.748 -17.693 1   29.492 ? 373  LYS B C   1 
ATOM   7060 O  O   . LYS B 1 381 ? -33.232 -17.59  -17.268 1   31.889 ? 373  LYS B O   1 
ATOM   7061 C  CB  . LYS B 1 381 ? -31.451 -20.508 -17.412 1   31.806 ? 373  LYS B CB  1 
ATOM   7062 C  CG  . LYS B 1 381 ? -30.484 -21.409 -18.123 1   31.259 ? 373  LYS B CG  1 
ATOM   7063 C  CD  . LYS B 1 381 ? -30.5   -22.758 -17.406 1   37.004 ? 373  LYS B CD  1 
ATOM   7064 C  CE  . LYS B 1 381 ? -29.691 -23.802 -18.092 1   44.935 ? 373  LYS B CE  1 
ATOM   7065 N  NZ  . LYS B 1 381 ? -30.573 -24.455 -19.066 1   53.209 ? 373  LYS B NZ  1 
ATOM   7066 N  N   . ASP B 1 382 ? -34.367 -19.503 -17.606 1   28.513 ? 374  ASP B N   1 
ATOM   7067 C  CA  . ASP B 1 382 ? -35.538 -19.082 -16.869 1   28.594 ? 374  ASP B CA  1 
ATOM   7068 C  C   . ASP B 1 382 ? -35.197 -19.115 -15.369 1   27.887 ? 374  ASP B C   1 
ATOM   7069 O  O   . ASP B 1 382 ? -34.897 -20.192 -14.834 1   27.805 ? 374  ASP B O   1 
ATOM   7070 C  CB  . ASP B 1 382 ? -36.714 -19.981 -17.232 1   30.799 ? 374  ASP B CB  1 
ATOM   7071 C  CG  . ASP B 1 382 ? -38.043 -19.712 -16.547 1   37.847 ? 374  ASP B CG  1 
ATOM   7072 O  OD1 . ASP B 1 382 ? -38.105 -18.873 -15.618 1   34.399 ? 374  ASP B OD1 1 
ATOM   7073 O  OD2 . ASP B 1 382 ? -39.053 -20.295 -17.017 1   45.871 ? 374  ASP B OD2 1 
ATOM   7074 N  N   . ASN B 1 383 ? -35.3   -17.943 -14.709 1   28.555 ? 375  ASN B N   1 
ATOM   7075 C  CA  . ASN B 1 383 ? -34.946 -17.829 -13.285 1   29.9   ? 375  ASN B CA  1 
ATOM   7076 C  C   . ASN B 1 383 ? -35.928 -18.603 -12.398 1   31.393 ? 375  ASN B C   1 
ATOM   7077 O  O   . ASN B 1 383 ? -35.614 -18.874 -11.242 1   29.497 ? 375  ASN B O   1 
ATOM   7078 C  CB  . ASN B 1 383 ? -34.756 -16.382 -12.828 1   28.951 ? 375  ASN B CB  1 
ATOM   7079 C  CG  . ASN B 1 383 ? -36.054 -15.61  -12.906 1   32.968 ? 375  ASN B CG  1 
ATOM   7080 O  OD1 . ASN B 1 383 ? -36.576 -15.41  -14.012 1   33.079 ? 375  ASN B OD1 1 
ATOM   7081 N  ND2 . ASN B 1 383 ? -36.648 -15.223 -11.782 1   26.614 ? 375  ASN B ND2 1 
ATOM   7082 N  N   . ASN B 1 384 ? -37.107 -19.001 -12.921 1   28.534 ? 376  ASN B N   1 
ATOM   7083 C  CA  . ASN B 1 384 ? -37.994 -19.875 -12.149 1   28.791 ? 376  ASN B CA  1 
ATOM   7084 C  C   . ASN B 1 384 ? -37.535 -21.328 -12.075 1   28.434 ? 376  ASN B C   1 
ATOM   7085 O  O   . ASN B 1 384 ? -38.087 -22.087 -11.271 1   30.083 ? 376  ASN B O   1 
ATOM   7086 C  CB  . ASN B 1 384 ? -39.415 -19.885 -12.691 1   32.684 ? 376  ASN B CB  1 
ATOM   7087 C  CG  . ASN B 1 384 ? -40.049 -18.533 -12.554 1   37.153 ? 376  ASN B CG  1 
ATOM   7088 O  OD1 . ASN B 1 384 ? -39.912 -17.868 -11.528 1   39.371 ? 376  ASN B OD1 1 
ATOM   7089 N  ND2 . ASN B 1 384 ? -40.735 -18.1   -13.596 1   42.892 ? 376  ASN B ND2 1 
ATOM   7090 N  N   . GLU B 1 385 ? -36.577 -21.739 -12.917 1   30.063 ? 377  GLU B N   1 
ATOM   7091 C  CA  . GLU B 1 385 ? -36.066 -23.095 -12.872 1   28.417 ? 377  GLU B CA  1 
ATOM   7092 C  C   . GLU B 1 385 ? -34.994 -23.195 -11.78  1   29.337 ? 377  GLU B C   1 
ATOM   7093 O  O   . GLU B 1 385 ? -34.102 -22.345 -11.728 1   30.274 ? 377  GLU B O   1 
ATOM   7094 C  CB  . GLU B 1 385 ? -35.509 -23.416 -14.256 1   31.791 ? 377  GLU B CB  1 
ATOM   7095 C  CG  . GLU B 1 385 ? -34.883 -24.8   -14.403 1   39.512 ? 377  GLU B CG  1 
ATOM   7096 C  CD  . GLU B 1 385 ? -34.265 -24.962 -15.782 1   38.154 ? 377  GLU B CD  1 
ATOM   7097 O  OE1 . GLU B 1 385 ? -35.033 -24.786 -16.757 1   45.441 ? 377  GLU B OE1 1 
ATOM   7098 O  OE2 . GLU B 1 385 ? -33.056 -25.263 -15.898 1   36.344 ? 377  GLU B OE2 1 
ATOM   7099 N  N   . GLN B 1 386 ? -35.08  -24.263 -10.97  1   24.938 ? 378  GLN B N   1 
ATOM   7100 C  CA  . GLN B 1 386 ? -34.094 -24.528 -9.924  1   24.127 ? 378  GLN B CA  1 
ATOM   7101 C  C   . GLN B 1 386 ? -32.692 -24.549 -10.522 1   27.337 ? 378  GLN B C   1 
ATOM   7102 O  O   . GLN B 1 386 ? -32.431 -25.17  -11.557 1   26.291 ? 378  GLN B O   1 
ATOM   7103 C  CB  . GLN B 1 386 ? -34.393 -25.849 -9.212  1   26.07  ? 378  GLN B CB  1 
ATOM   7104 C  CG  . GLN B 1 386 ? -33.524 -26.122 -7.982  1   25.766 ? 378  GLN B CG  1 
ATOM   7105 C  CD  . GLN B 1 386 ? -33.89  -27.423 -7.3    1   31.915 ? 378  GLN B CD  1 
ATOM   7106 O  OE1 . GLN B 1 386 ? -34.856 -27.515 -6.545  1   36.455 ? 378  GLN B OE1 1 
ATOM   7107 N  NE2 . GLN B 1 386 ? -33.083 -28.436 -7.517  1   34.383 ? 378  GLN B NE2 1 
ATOM   7108 N  N   . LEU B 1 387 ? -31.756 -23.858 -9.845  1   25.511 ? 379  LEU B N   1 
ATOM   7109 C  CA  . LEU B 1 387 ? -30.347 -23.834 -10.24  1   23.781 ? 379  LEU B CA  1 
ATOM   7110 C  C   . LEU B 1 387 ? -29.755 -25.245 -10.224 1   21.387 ? 379  LEU B C   1 
ATOM   7111 O  O   . LEU B 1 387 ? -30.175 -26.09  -9.408  1   23.395 ? 379  LEU B O   1 
ATOM   7112 C  CB  . LEU B 1 387 ? -29.558 -22.912 -9.289  1   21.914 ? 379  LEU B CB  1 
ATOM   7113 C  CG  . LEU B 1 387 ? -29.816 -21.412 -9.457  1   21.163 ? 379  LEU B CG  1 
ATOM   7114 C  CD1 . LEU B 1 387 ? -29.125 -20.72  -8.234  1   20.677 ? 379  LEU B CD1 1 
ATOM   7115 C  CD2 . LEU B 1 387 ? -29.152 -20.914 -10.766 1   20.236 ? 379  LEU B CD2 1 
ATOM   7116 N  N   . PRO B 1 388 ? -28.699 -25.51  -11.031 1   25.257 ? 380  PRO B N   1 
ATOM   7117 C  CA  . PRO B 1 388 ? -27.96  -26.767 -10.974 1   24.322 ? 380  PRO B CA  1 
ATOM   7118 C  C   . PRO B 1 388 ? -27.247 -26.883 -9.621  1   26.518 ? 380  PRO B C   1 
ATOM   7119 O  O   . PRO B 1 388 ? -26.924 -25.866 -8.981  1   27.563 ? 380  PRO B O   1 
ATOM   7120 C  CB  . PRO B 1 388 ? -26.971 -26.655 -12.184 1   23.567 ? 380  PRO B CB  1 
ATOM   7121 C  CG  . PRO B 1 388 ? -26.778 -25.174 -12.345 1   26.664 ? 380  PRO B CG  1 
ATOM   7122 C  CD  . PRO B 1 388 ? -28.138 -24.585 -12.048 1   24.785 ? 380  PRO B CD  1 
ATOM   7123 N  N   . ASP B 1 389 ? -27.003 -28.123 -9.196  1   27.943 ? 381  ASP B N   1 
ATOM   7124 C  CA  . ASP B 1 389 ? -26.32  -28.348 -7.933  1   27.555 ? 381  ASP B CA  1 
ATOM   7125 C  C   . ASP B 1 389 ? -24.924 -27.756 -8.031  1   28.213 ? 381  ASP B C   1 
ATOM   7126 O  O   . ASP B 1 389 ? -24.27  -27.849 -9.073  1   27.839 ? 381  ASP B O   1 
ATOM   7127 C  CB  . ASP B 1 389 ? -26.193 -29.832 -7.618  1   27.202 ? 381  ASP B CB  1 
ATOM   7128 C  CG  . ASP B 1 389 ? -27.507 -30.552 -7.332  1   30.404 ? 381  ASP B CG  1 
ATOM   7129 O  OD1 . ASP B 1 389 ? -28.535 -29.884 -7.095  1   27.268 ? 381  ASP B OD1 1 
ATOM   7130 O  OD2 . ASP B 1 389 ? -27.503 -31.81  -7.401  1   37.52  ? 381  ASP B OD2 1 
ATOM   7131 N  N   . PRO B 1 390 ? -24.413 -27.085 -6.964  1   25.704 ? 382  PRO B N   1 
ATOM   7132 C  CA  . PRO B 1 390 ? -23.077 -26.516 -7.042  1   26.393 ? 382  PRO B CA  1 
ATOM   7133 C  C   . PRO B 1 390 ? -22.03  -27.623 -7.067  1   25.54  ? 382  PRO B C   1 
ATOM   7134 O  O   . PRO B 1 390 ? -22.285 -28.724 -6.589  1   25.5   ? 382  PRO B O   1 
ATOM   7135 C  CB  . PRO B 1 390 ? -23.027 -25.65  -5.755  1   22.527 ? 382  PRO B CB  1 
ATOM   7136 C  CG  . PRO B 1 390 ? -23.937 -26.341 -4.781  1   24.995 ? 382  PRO B CG  1 
ATOM   7137 C  CD  . PRO B 1 390 ? -25.072 -26.848 -5.659  1   25.963 ? 382  PRO B CD  1 
ATOM   7138 N  N   . GLU B 1 391 ? -20.894 -27.314 -7.695  1   23.707 ? 383  GLU B N   1 
ATOM   7139 C  CA  . GLU B 1 391 ? -19.779 -28.239 -7.781  1   23.7   ? 383  GLU B CA  1 
ATOM   7140 C  C   . GLU B 1 391 ? -18.968 -28.16  -6.483  1   24.881 ? 383  GLU B C   1 
ATOM   7141 O  O   . GLU B 1 391 ? -18.662 -27.049 -6.02   1   22.677 ? 383  GLU B O   1 
ATOM   7142 C  CB  . GLU B 1 391 ? -18.95  -27.816 -8.995  1   25.017 ? 383  GLU B CB  1 
ATOM   7143 C  CG  . GLU B 1 391 ? -17.781 -28.776 -9.171  1   29.848 ? 383  GLU B CG  1 
ATOM   7144 C  CD  . GLU B 1 391 ? -16.826 -28.385 -10.27  1   32.754 ? 383  GLU B CD  1 
ATOM   7145 O  OE1 . GLU B 1 391 ? -17.065 -27.353 -10.966 1   36.832 ? 383  GLU B OE1 1 
ATOM   7146 O  OE2 . GLU B 1 391 ? -15.83  -29.135 -10.365 1   37.082 ? 383  GLU B OE2 1 
ATOM   7147 N  N   . VAL B 1 392 ? -18.592 -29.335 -5.955  1   23.482 ? 384  VAL B N   1 
ATOM   7148 C  CA  . VAL B 1 392 ? -17.755 -29.411 -4.768  1   24.905 ? 384  VAL B CA  1 
ATOM   7149 C  C   . VAL B 1 392 ? -16.315 -29.098 -5.176  1   26.875 ? 384  VAL B C   1 
ATOM   7150 O  O   . VAL B 1 392 ? -15.727 -29.815 -5.987  1   26.485 ? 384  VAL B O   1 
ATOM   7151 C  CB  . VAL B 1 392 ? -17.869 -30.737 -3.989  1   23.683 ? 384  VAL B CB  1 
ATOM   7152 C  CG1 . VAL B 1 392 ? -16.958 -30.723 -2.747  1   23.087 ? 384  VAL B CG1 1 
ATOM   7153 C  CG2 . VAL B 1 392 ? -19.308 -30.994 -3.61   1   24.405 ? 384  VAL B CG2 1 
ATOM   7154 N  N   . ILE B 1 393 ? -15.746 -28.017 -4.597  1   22.821 ? 385  ILE B N   1 
ATOM   7155 C  CA  . ILE B 1 393 ? -14.391 -27.599 -4.883  1   23.924 ? 385  ILE B CA  1 
ATOM   7156 C  C   . ILE B 1 393 ? -13.443 -28.13  -3.805  1   21.435 ? 385  ILE B C   1 
ATOM   7157 O  O   . ILE B 1 393 ? -12.414 -28.705 -4.134  1   24.705 ? 385  ILE B O   1 
ATOM   7158 C  CB  . ILE B 1 393 ? -14.309 -26.066 -5.068  1   23.752 ? 385  ILE B CB  1 
ATOM   7159 C  CG1 . ILE B 1 393 ? -15.258 -25.566 -6.195  1   24.882 ? 385  ILE B CG1 1 
ATOM   7160 C  CG2 . ILE B 1 393 ? -12.867 -25.586 -5.248  1   25.412 ? 385  ILE B CG2 1 
ATOM   7161 C  CD1 . ILE B 1 393 ? -15.087 -26.225 -7.563  1   26.169 ? 385  ILE B CD1 1 
ATOM   7162 N  N   . LEU B 1 394 ? -13.822 -27.954 -2.522  1   24.846 ? 386  LEU B N   1 
ATOM   7163 C  CA  . LEU B 1 394 ? -13.117 -28.552 -1.401  1   24.977 ? 386  LEU B CA  1 
ATOM   7164 C  C   . LEU B 1 394 ? -14.129 -29.306 -0.562  1   23.278 ? 386  LEU B C   1 
ATOM   7165 O  O   . LEU B 1 394 ? -15.129 -28.738 -0.125  1   25.282 ? 386  LEU B O   1 
ATOM   7166 C  CB  . LEU B 1 394 ? -12.363 -27.549 -0.52   1   27.189 ? 386  LEU B CB  1 
ATOM   7167 C  CG  . LEU B 1 394 ? -11.239 -26.748 -1.187  1   30.054 ? 386  LEU B CG  1 
ATOM   7168 C  CD1 . LEU B 1 394 ? -10.656 -25.816 -0.12   1   32.814 ? 386  LEU B CD1 1 
ATOM   7169 C  CD2 . LEU B 1 394 ? -10.149 -27.601 -1.827  1   34.205 ? 386  LEU B CD2 1 
ATOM   7170 N  N   . ASP B 1 395 ? -13.884 -30.605 -0.386  1   26.337 ? 387  ASP B N   1 
ATOM   7171 C  CA  . ASP B 1 395 ? -14.719 -31.388 0.509   1   25.19  ? 387  ASP B CA  1 
ATOM   7172 C  C   . ASP B 1 395 ? -14.144 -31.335 1.923   1   30.636 ? 387  ASP B C   1 
ATOM   7173 O  O   . ASP B 1 395 ? -13.797 -32.36  2.502   1   27.357 ? 387  ASP B O   1 
ATOM   7174 C  CB  . ASP B 1 395 ? -14.88  -32.813 -0.022  1   28.078 ? 387  ASP B CB  1 
ATOM   7175 C  CG  . ASP B 1 395 ? -15.978 -33.596 0.676   1   32.131 ? 387  ASP B CG  1 
ATOM   7176 O  OD1 . ASP B 1 395 ? -16.842 -32.976 1.35    1   29.796 ? 387  ASP B OD1 1 
ATOM   7177 O  OD2 . ASP B 1 395 ? -15.969 -34.83  0.576   1   40.318 ? 387  ASP B OD2 1 
ATOM   7178 N  N   . THR B 1 396 ? -14.047 -30.121 2.488   1   27.355 ? 388  THR B N   1 
ATOM   7179 C  CA  . THR B 1 396 ? -13.574 -29.925 3.849   1   26.834 ? 388  THR B CA  1 
ATOM   7180 C  C   . THR B 1 396 ? -14.277 -28.67  4.358   1   25.757 ? 388  THR B C   1 
ATOM   7181 O  O   . THR B 1 396 ? -14.6   -27.778 3.557   1   23.046 ? 388  THR B O   1 
ATOM   7182 C  CB  . THR B 1 396 ? -12.039 -29.856 3.982   1   38.655 ? 388  THR B CB  1 
ATOM   7183 O  OG1 . THR B 1 396 ? -11.702 -30.091 5.354   1   37.079 ? 388  THR B OG1 1 
ATOM   7184 C  CG2 . THR B 1 396 ? -11.421 -28.516 3.623   1   33.543 ? 388  THR B CG2 1 
ATOM   7185 N  N   . PRO B 1 397 ? -14.587 -28.592 5.668   1   23.543 ? 389  PRO B N   1 
ATOM   7186 C  CA  . PRO B 1 397 ? -15.176 -27.363 6.214   1   23.128 ? 389  PRO B CA  1 
ATOM   7187 C  C   . PRO B 1 397 ? -14.244 -26.192 5.915   1   21.079 ? 389  PRO B C   1 
ATOM   7188 O  O   . PRO B 1 397 ? -13.043 -26.248 6.171   1   22.931 ? 389  PRO B O   1 
ATOM   7189 C  CB  . PRO B 1 397 ? -15.341 -27.685 7.705   1   23.631 ? 389  PRO B CB  1 
ATOM   7190 C  CG  . PRO B 1 397 ? -15.403 -29.245 7.767   1   25.523 ? 389  PRO B CG  1 
ATOM   7191 C  CD  . PRO B 1 397 ? -14.48  -29.677 6.681   1   26.628 ? 389  PRO B CD  1 
ATOM   7192 N  N   . SER B 1 398 ? -14.851 -25.149 5.332   1   20.517 ? 390  SER B N   1 
ATOM   7193 C  CA  . SER B 1 398 ? -14.18  -24.018 4.721   1   20.917 ? 390  SER B CA  1 
ATOM   7194 C  C   . SER B 1 398 ? -14.964 -22.769 5.085   1   20.693 ? 390  SER B C   1 
ATOM   7195 O  O   . SER B 1 398 ? -16.193 -22.762 5.03    1   21.095 ? 390  SER B O   1 
ATOM   7196 C  CB  . SER B 1 398 ? -14.22  -24.167 3.227   1   20.684 ? 390  SER B CB  1 
ATOM   7197 O  OG  . SER B 1 398 ? -13.464 -25.29  2.82    1   21.147 ? 390  SER B OG  1 
ATOM   7198 N  N   . GLU B 1 399 ? -14.25  -21.701 5.472   1   19.304 ? 391  GLU B N   1 
ATOM   7199 C  CA  . GLU B 1 399 ? -14.996 -20.485 5.778   1   18.814 ? 391  GLU B CA  1 
ATOM   7200 C  C   . GLU B 1 399 ? -14.042 -19.302 5.572   1   18.325 ? 391  GLU B C   1 
ATOM   7201 O  O   . GLU B 1 399 ? -12.888 -19.488 5.205   1   18.729 ? 391  GLU B O   1 
ATOM   7202 C  CB  . GLU B 1 399 ? -15.719 -20.542 7.14    1   19.943 ? 391  GLU B CB  1 
ATOM   7203 C  CG  . GLU B 1 399 ? -17.23  -20.292 6.997   1   21.585 ? 391  GLU B CG  1 
ATOM   7204 C  CD  . GLU B 1 399 ? -17.503 -18.984 6.285   1   22.091 ? 391  GLU B CD  1 
ATOM   7205 O  OE1 . GLU B 1 399 ? -17.207 -17.957 6.919   1   24.992 ? 391  GLU B OE1 1 
ATOM   7206 O  OE2 . GLU B 1 399 ? -17.938 -18.939 5.143   1   24.806 ? 391  GLU B OE2 1 
ATOM   7207 N  N   . PHE B 1 400 ? -14.567 -18.09  5.817   1   20.795 ? 392  PHE B N   1 
ATOM   7208 C  CA  . PHE B 1 400 ? -13.813 -16.843 5.744   1   18.998 ? 392  PHE B CA  1 
ATOM   7209 C  C   . PHE B 1 400 ? -12.877 -16.808 4.533   1   17.979 ? 392  PHE B C   1 
ATOM   7210 O  O   . PHE B 1 400 ? -11.669 -16.585 4.684   1   17.368 ? 392  PHE B O   1 
ATOM   7211 C  CB  . PHE B 1 400 ? -13.049 -16.625 7.055   1   17.544 ? 392  PHE B CB  1 
ATOM   7212 C  CG  . PHE B 1 400 ? -13.95  -16.369 8.25    1   17.968 ? 392  PHE B CG  1 
ATOM   7213 C  CD1 . PHE B 1 400 ? -14.737 -15.212 8.291   1   19.086 ? 392  PHE B CD1 1 
ATOM   7214 C  CD2 . PHE B 1 400 ? -14.005 -17.276 9.319   1   19.36  ? 392  PHE B CD2 1 
ATOM   7215 C  CE1 . PHE B 1 400 ? -15.596 -14.948 9.361   1   19.606 ? 392  PHE B CE1 1 
ATOM   7216 C  CE2 . PHE B 1 400 ? -14.875 -17.008 10.386  1   17.874 ? 392  PHE B CE2 1 
ATOM   7217 C  CZ  . PHE B 1 400 ? -15.626 -15.823 10.438  1   18.713 ? 392  PHE B CZ  1 
ATOM   7218 N  N   . PRO B 1 401 ? -13.378 -17.007 3.289   1   18.093 ? 393  PRO B N   1 
ATOM   7219 C  CA  . PRO B 1 401 ? -12.515 -16.88  2.121   1   18.052 ? 393  PRO B CA  1 
ATOM   7220 C  C   . PRO B 1 401 ? -12.25  -15.422 1.74    1   16.498 ? 393  PRO B C   1 
ATOM   7221 O  O   . PRO B 1 401 ? -13.131 -14.587 1.909   1   17.943 ? 393  PRO B O   1 
ATOM   7222 C  CB  . PRO B 1 401 ? -13.37  -17.568 1.021   1   17.373 ? 393  PRO B CB  1 
ATOM   7223 C  CG  . PRO B 1 401 ? -14.787 -17.236 1.418   1   19.336 ? 393  PRO B CG  1 
ATOM   7224 C  CD  . PRO B 1 401 ? -14.771 -17.38  2.936   1   19.648 ? 393  PRO B CD  1 
ATOM   7225 N  N   . GLN B 1 402 ? -11.028 -15.169 1.217   1   17.241 ? 394  GLN B N   1 
ATOM   7226 C  CA  . GLN B 1 402 ? -10.699 -13.893 0.592   1   16.921 ? 394  GLN B CA  1 
ATOM   7227 C  C   . GLN B 1 402 ? -9.957  -14.199 -0.704  1   17.443 ? 394  GLN B C   1 
ATOM   7228 O  O   . GLN B 1 402 ? -9.615  -15.355 -0.976  1   19.263 ? 394  GLN B O   1 
ATOM   7229 C  CB  . GLN B 1 402 ? -9.849  -12.984 1.5     1   18.471 ? 394  GLN B CB  1 
ATOM   7230 C  CG  . GLN B 1 402 ? -10.666 -12.351 2.622   1   18.198 ? 394  GLN B CG  1 
ATOM   7231 C  CD  . GLN B 1 402 ? -10.009 -11.14  3.229   1   19.641 ? 394  GLN B CD  1 
ATOM   7232 O  OE1 . GLN B 1 402 ? -9.054  -10.573 2.682   1   18.855 ? 394  GLN B OE1 1 
ATOM   7233 N  NE2 . GLN B 1 402 ? -10.629 -10.648 4.304   1   16.658 ? 394  GLN B NE2 1 
ATOM   7234 N  N   . ILE B 1 403 ? -9.736  -13.142 -1.494  1   17.404 ? 395  ILE B N   1 
ATOM   7235 C  CA  . ILE B 1 403 ? -9.128  -13.32  -2.814  1   18.109 ? 395  ILE B CA  1 
ATOM   7236 C  C   . ILE B 1 403 ? -8.022  -12.283 -2.963  1   20.584 ? 395  ILE B C   1 
ATOM   7237 O  O   . ILE B 1 403 ? -7.659  -11.603 -1.997  1   18.48  ? 395  ILE B O   1 
ATOM   7238 C  CB  . ILE B 1 403 ? -10.195 -13.195 -3.926  1   19.502 ? 395  ILE B CB  1 
ATOM   7239 C  CG1 . ILE B 1 403 ? -10.755 -11.747 -4.115  1   19.851 ? 395  ILE B CG1 1 
ATOM   7240 C  CG2 . ILE B 1 403 ? -11.287 -14.262 -3.774  1   20.3   ? 395  ILE B CG2 1 
ATOM   7241 C  CD1 . ILE B 1 403 ? -11.177 -11.521 -5.573  1   21.128 ? 395  ILE B CD1 1 
ATOM   7242 N  N   . ASP B 1 404 ? -7.433  -12.203 -4.179  1   19.13  ? 396  ASP B N   1 
ATOM   7243 C  CA  . ASP B 1 404 ? -6.539  -11.108 -4.51   1   18.874 ? 396  ASP B CA  1 
ATOM   7244 C  C   . ASP B 1 404 ? -7.385  -9.976  -5.074  1   20.419 ? 396  ASP B C   1 
ATOM   7245 O  O   . ASP B 1 404 ? -7.91   -10.085 -6.199  1   21.096 ? 396  ASP B O   1 
ATOM   7246 C  CB  . ASP B 1 404 ? -5.487  -11.617 -5.495  1   19.106 ? 396  ASP B CB  1 
ATOM   7247 C  CG  . ASP B 1 404 ? -4.461  -10.631 -6.012  1   18.772 ? 396  ASP B CG  1 
ATOM   7248 O  OD1 . ASP B 1 404 ? -4.637  -9.426  -5.861  1   20.342 ? 396  ASP B OD1 1 
ATOM   7249 O  OD2 . ASP B 1 404 ? -3.463  -11.107 -6.61   1   21.59  ? 396  ASP B OD2 1 
ATOM   7250 N  N   . ASN B 1 405 ? -7.567  -8.909  -4.29   1   19.229 ? 397  ASN B N   1 
ATOM   7251 C  CA  . ASN B 1 405 ? -8.553  -7.887  -4.609  1   20.758 ? 397  ASN B CA  1 
ATOM   7252 C  C   . ASN B 1 405 ? -8.203  -7.083  -5.866  1   20.001 ? 397  ASN B C   1 
ATOM   7253 O  O   . ASN B 1 405 ? -9.043  -6.327  -6.358  1   20.425 ? 397  ASN B O   1 
ATOM   7254 C  CB  . ASN B 1 405 ? -8.742  -6.949  -3.416  1   22.24  ? 397  ASN B CB  1 
ATOM   7255 C  CG  . ASN B 1 405 ? -9.516  -7.608  -2.291  1   23.476 ? 397  ASN B CG  1 
ATOM   7256 O  OD1 . ASN B 1 405 ? -9.456  -7.143  -1.133  1   25.422 ? 397  ASN B OD1 1 
ATOM   7257 N  ND2 . ASN B 1 405 ? -10.246 -8.661  -2.601  1   20.001 ? 397  ASN B ND2 1 
ATOM   7258 N  N   . ARG B 1 406 ? -6.99   -7.289  -6.403  1   18.657 ? 398  ARG B N   1 
ATOM   7259 C  CA  . ARG B 1 406 ? -6.677  -6.725  -7.72   1   21.187 ? 398  ARG B CA  1 
ATOM   7260 C  C   . ARG B 1 406 ? -7.558  -7.365  -8.798  1   21.46  ? 398  ARG B C   1 
ATOM   7261 O  O   . ARG B 1 406 ? -7.653  -6.817  -9.906  1   23.976 ? 398  ARG B O   1 
ATOM   7262 C  CB  . ARG B 1 406 ? -5.188  -6.95   -7.992  1   20.149 ? 398  ARG B CB  1 
ATOM   7263 C  CG  . ARG B 1 406 ? -4.279  -6.104  -7.102  1   20.556 ? 398  ARG B CG  1 
ATOM   7264 C  CD  . ARG B 1 406 ? -2.796  -6.409  -7.294  1   21.991 ? 398  ARG B CD  1 
ATOM   7265 N  NE  . ARG B 1 406 ? -2.461  -7.826  -7.124  1   21.861 ? 398  ARG B NE  1 
ATOM   7266 C  CZ  . ARG B 1 406 ? -1.381  -8.424  -7.622  1   21.851 ? 398  ARG B CZ  1 
ATOM   7267 N  NH1 . ARG B 1 406 ? -0.458  -7.692  -8.263  1   23.15  ? 398  ARG B NH1 1 
ATOM   7268 N  NH2 . ARG B 1 406 ? -1.244  -9.734  -7.488  1   22.515 ? 398  ARG B NH2 1 
ATOM   7269 N  N   . PHE B 1 407 ? -8.25   -8.466  -8.455  1   22.051 ? 399  PHE B N   1 
ATOM   7270 C  CA  . PHE B 1 407 ? -9.161  -9.168  -9.356  1   20.708 ? 399  PHE B CA  1 
ATOM   7271 C  C   . PHE B 1 407 ? -10.598 -9.123  -8.827  1   20.403 ? 399  PHE B C   1 
ATOM   7272 O  O   . PHE B 1 407 ? -11.456 -9.886  -9.28   1   20.917 ? 399  PHE B O   1 
ATOM   7273 C  CB  . PHE B 1 407 ? -8.667  -10.612 -9.562  1   23.279 ? 399  PHE B CB  1 
ATOM   7274 C  CG  . PHE B 1 407 ? -7.281  -10.625 -10.186 1   23.21  ? 399  PHE B CG  1 
ATOM   7275 C  CD1 . PHE B 1 407 ? -6.133  -10.435 -9.408  1   22.706 ? 399  PHE B CD1 1 
ATOM   7276 C  CD2 . PHE B 1 407 ? -7.144  -10.759 -11.578 1   25.634 ? 399  PHE B CD2 1 
ATOM   7277 C  CE1 . PHE B 1 407 ? -4.864  -10.338 -9.987  1   26.327 ? 399  PHE B CE1 1 
ATOM   7278 C  CE2 . PHE B 1 407 ? -5.871  -10.694 -12.161 1   24.221 ? 399  PHE B CE2 1 
ATOM   7279 C  CZ  . PHE B 1 407 ? -4.732  -10.5   -11.371 1   26.936 ? 399  PHE B CZ  1 
ATOM   7280 N  N   . MET B 1 408 ? -10.902 -8.197  -7.904  1   18.325 ? 400  MET B N   1 
ATOM   7281 C  CA  . MET B 1 408 ? -12.255 -8.086  -7.392  1   18.173 ? 400  MET B CA  1 
ATOM   7282 C  C   . MET B 1 408 ? -13.189 -7.53   -8.474  1   20.57  ? 400  MET B C   1 
ATOM   7283 O  O   . MET B 1 408 ? -12.955 -6.445  -9.022  1   20.488 ? 400  MET B O   1 
ATOM   7284 C  CB  . MET B 1 408 ? -12.295 -7.163  -6.154  1   18.335 ? 400  MET B CB  1 
ATOM   7285 C  CG  . MET B 1 408 ? -13.699 -6.993  -5.573  1   17.826 ? 400  MET B CG  1 
ATOM   7286 S  SD  . MET B 1 408 ? -14.618 -8.533  -5.225  1   20.16  ? 400  MET B SD  1 
ATOM   7287 C  CE  . MET B 1 408 ? -13.853 -9.082  -3.692  1   18.307 ? 400  MET B CE  1 
ATOM   7288 N  N   . GLY B 1 409 ? -14.299 -8.257  -8.705  1   19.984 ? 401  GLY B N   1 
ATOM   7289 C  CA  . GLY B 1 409 ? -15.298 -7.886  -9.698  1   21.936 ? 401  GLY B CA  1 
ATOM   7290 C  C   . GLY B 1 409 ? -14.929 -8.266  -11.143 1   20.497 ? 401  GLY B C   1 
ATOM   7291 O  O   . GLY B 1 409 ? -15.659 -7.84   -12.049 1   21.819 ? 401  GLY B O   1 
ATOM   7292 N  N   . VAL B 1 410 ? -13.828 -8.989  -11.328 1   20.331 ? 402  VAL B N   1 
ATOM   7293 C  CA  . VAL B 1 410 ? -13.479 -9.617  -12.606 1   21.463 ? 402  VAL B CA  1 
ATOM   7294 C  C   . VAL B 1 410 ? -13.101 -11.081 -12.379 1   23.776 ? 402  VAL B C   1 
ATOM   7295 O  O   . VAL B 1 410 ? -13.061 -11.583 -11.248 1   20.136 ? 402  VAL B O   1 
ATOM   7296 C  CB  . VAL B 1 410 ? -12.351 -8.807  -13.291 1   21.716 ? 402  VAL B CB  1 
ATOM   7297 C  CG1 . VAL B 1 410 ? -12.748 -7.37   -13.62  1   22.72  ? 402  VAL B CG1 1 
ATOM   7298 C  CG2 . VAL B 1 410 ? -11.034 -8.844  -12.501 1   20.367 ? 402  VAL B CG2 1 
ATOM   7299 N  N   . GLU B 1 411 ? -12.724 -11.78  -13.466 1   21.071 ? 403  GLU B N   1 
ATOM   7300 C  CA  . GLU B 1 411 ? -12.284 -13.134 -13.35  1   19.441 ? 403  GLU B CA  1 
ATOM   7301 C  C   . GLU B 1 411 ? -11.104 -13.213 -12.377 1   21.506 ? 403  GLU B C   1 
ATOM   7302 O  O   . GLU B 1 411 ? -10.114 -12.486 -12.496 1   24.108 ? 403  GLU B O   1 
ATOM   7303 C  CB  . GLU B 1 411 ? -11.955 -13.768 -14.708 1   22.917 ? 403  GLU B CB  1 
ATOM   7304 C  CG  . GLU B 1 411 ? -11.582 -15.245 -14.569 1   24.86  ? 403  GLU B CG  1 
ATOM   7305 C  CD  . GLU B 1 411 ? -11.333 -16.002 -15.872 1   28.943 ? 403  GLU B CD  1 
ATOM   7306 O  OE1 . GLU B 1 411 ? -11.692 -15.412 -16.917 1   32.952 ? 403  GLU B OE1 1 
ATOM   7307 O  OE2 . GLU B 1 411 ? -10.827 -17.14  -15.824 1   30.351 ? 403  GLU B OE2 1 
ATOM   7308 N  N   . TYR B 1 412 ? -11.244 -14.156 -11.436 1   20.665 ? 404  TYR B N   1 
ATOM   7309 C  CA  . TYR B 1 412 ? -10.239 -14.379 -10.41  1   20.294 ? 404  TYR B CA  1 
ATOM   7310 C  C   . TYR B 1 412 ? -9.954  -15.872 -10.348 1   23.021 ? 404  TYR B C   1 
ATOM   7311 O  O   . TYR B 1 412 ? -10.803 -16.685 -10.754 1   23.092 ? 404  TYR B O   1 
ATOM   7312 C  CB  . TYR B 1 412 ? -10.667 -13.776 -9.06   1   21.016 ? 404  TYR B CB  1 
ATOM   7313 C  CG  . TYR B 1 412 ? -11.645 -14.677 -8.31   1   20.665 ? 404  TYR B CG  1 
ATOM   7314 C  CD1 . TYR B 1 412 ? -12.995 -14.742 -8.67   1   20.142 ? 404  TYR B CD1 1 
ATOM   7315 C  CD2 . TYR B 1 412 ? -11.197 -15.5   -7.273  1   18.556 ? 404  TYR B CD2 1 
ATOM   7316 C  CE1 . TYR B 1 412 ? -13.869 -15.628 -8.044  1   20.744 ? 404  TYR B CE1 1 
ATOM   7317 C  CE2 . TYR B 1 412 ? -12.071 -16.347 -6.608  1   18.24  ? 404  TYR B CE2 1 
ATOM   7318 C  CZ  . TYR B 1 412 ? -13.392 -16.436 -7.019  1   20.272 ? 404  TYR B CZ  1 
ATOM   7319 O  OH  . TYR B 1 412 ? -14.253 -17.288 -6.392  1   20.849 ? 404  TYR B OH  1 
ATOM   7320 N  N   . SER B 1 413 ? -8.803  -16.215 -9.773  1   21.404 ? 405  SER B N   1 
ATOM   7321 C  CA  . SER B 1 413 ? -8.332  -17.583 -9.657  1   22.456 ? 405  SER B CA  1 
ATOM   7322 C  C   . SER B 1 413 ? -7.986  -17.976 -8.207  1   22.111 ? 405  SER B C   1 
ATOM   7323 O  O   . SER B 1 413 ? -8.339  -19.082 -7.764  1   22.84  ? 405  SER B O   1 
ATOM   7324 C  CB  . SER B 1 413 ? -7.203  -17.853 -10.655 1   22.746 ? 405  SER B CB  1 
ATOM   7325 O  OG  . SER B 1 413 ? -6.687  -19.172 -10.466 1   23.342 ? 405  SER B OG  1 
ATOM   7326 N  N   . SER B 1 414 ? -7.184  -17.127 -7.528  1   21.047 ? 406  SER B N   1 
ATOM   7327 C  CA  . SER B 1 414 ? -6.73   -17.447 -6.171  1   21.373 ? 406  SER B CA  1 
ATOM   7328 C  C   . SER B 1 414 ? -7.841  -17.21  -5.152  1   19.468 ? 406  SER B C   1 
ATOM   7329 O  O   . SER B 1 414 ? -8.504  -16.178 -5.196  1   20.053 ? 406  SER B O   1 
ATOM   7330 C  CB  . SER B 1 414 ? -5.553  -16.609 -5.772  1   20.385 ? 406  SER B CB  1 
ATOM   7331 O  OG  . SER B 1 414 ? -4.312  -17.164 -6.193  1   22.791 ? 406  SER B OG  1 
ATOM   7332 N  N   . ALA B 1 415 ? -7.983  -18.183 -4.237  1   20.649 ? 407  ALA B N   1 
ATOM   7333 C  CA  . ALA B 1 415 ? -8.815  -17.992 -3.045  1   19.031 ? 407  ALA B CA  1 
ATOM   7334 C  C   . ALA B 1 415 ? -7.986  -18.444 -1.852  1   20.772 ? 407  ALA B C   1 
ATOM   7335 O  O   . ALA B 1 415 ? -7.318  -19.476 -1.888  1   21.428 ? 407  ALA B O   1 
ATOM   7336 C  CB  . ALA B 1 415 ? -10.108 -18.764 -3.11   1   20.303 ? 407  ALA B CB  1 
ATOM   7337 N  N   . PHE B 1 416 ? -8.029  -17.625 -0.789  1   20.157 ? 408  PHE B N   1 
ATOM   7338 C  CA  . PHE B 1 416 ? -7.377  -17.93  0.485   1   19.123 ? 408  PHE B CA  1 
ATOM   7339 C  C   . PHE B 1 416 ? -8.486  -18.27  1.475   1   17.892 ? 408  PHE B C   1 
ATOM   7340 O  O   . PHE B 1 416 ? -9.394  -17.461 1.707   1   19.743 ? 408  PHE B O   1 
ATOM   7341 C  CB  . PHE B 1 416 ? -6.602  -16.676 0.909   1   19.089 ? 408  PHE B CB  1 
ATOM   7342 C  CG  . PHE B 1 416 ? -5.575  -16.266 -0.126  1   20.759 ? 408  PHE B CG  1 
ATOM   7343 C  CD1 . PHE B 1 416 ? -4.397  -17.007 -0.292  1   18.706 ? 408  PHE B CD1 1 
ATOM   7344 C  CD2 . PHE B 1 416 ? -5.827  -15.158 -0.935  1   20.651 ? 408  PHE B CD2 1 
ATOM   7345 C  CE1 . PHE B 1 416 ? -3.466  -16.636 -1.261  1   19.821 ? 408  PHE B CE1 1 
ATOM   7346 C  CE2 . PHE B 1 416 ? -4.899  -14.798 -1.92   1   22.4   ? 408  PHE B CE2 1 
ATOM   7347 C  CZ  . PHE B 1 416 ? -3.716  -15.534 -2.048  1   20.833 ? 408  PHE B CZ  1 
ATOM   7348 N  N   . ILE B 1 417 ? -8.449  -19.504 1.999   1   18.664 ? 409  ILE B N   1 
ATOM   7349 C  CA  . ILE B 1 417 ? -9.624  -20.037 2.703   1   21.009 ? 409  ILE B CA  1 
ATOM   7350 C  C   . ILE B 1 417 ? -9.216  -20.537 4.095   1   20.135 ? 409  ILE B C   1 
ATOM   7351 O  O   . ILE B 1 417 ? -8.183  -21.184 4.251   1   19.345 ? 409  ILE B O   1 
ATOM   7352 C  CB  . ILE B 1 417 ? -10.248 -21.176 1.867   1   20.173 ? 409  ILE B CB  1 
ATOM   7353 C  CG1 . ILE B 1 417 ? -10.513 -20.745 0.406   1   21.164 ? 409  ILE B CG1 1 
ATOM   7354 C  CG2 . ILE B 1 417 ? -11.537 -21.659 2.516   1   20.041 ? 409  ILE B CG2 1 
ATOM   7355 C  CD1 . ILE B 1 417 ? -10.875 -21.915 -0.518  1   22.12  ? 409  ILE B CD1 1 
ATOM   7356 N  N   . ASN B 1 418 ? -10.049 -20.222 5.102   1   17.59  ? 410  ASN B N   1 
ATOM   7357 C  CA  . ASN B 1 418 ? -9.879  -20.741 6.461   1   18.741 ? 410  ASN B CA  1 
ATOM   7358 C  C   . ASN B 1 418 ? -10.479 -22.15  6.456   1   19.667 ? 410  ASN B C   1 
ATOM   7359 O  O   . ASN B 1 418 ? -11.629 -22.326 6.034   1   21.14  ? 410  ASN B O   1 
ATOM   7360 C  CB  . ASN B 1 418 ? -10.598 -19.778 7.414   1   18.165 ? 410  ASN B CB  1 
ATOM   7361 C  CG  . ASN B 1 418 ? -10.151 -19.72  8.852   1   17.804 ? 410  ASN B CG  1 
ATOM   7362 O  OD1 . ASN B 1 418 ? -10.786 -18.935 9.582   1   18.146 ? 410  ASN B OD1 1 
ATOM   7363 N  ND2 . ASN B 1 418 ? -9.127  -20.444 9.278   1   19.17  ? 410  ASN B ND2 1 
ATOM   7364 N  N   . VAL B 1 419 ? -9.699  -23.144 6.879   1   19.183 ? 411  VAL B N   1 
ATOM   7365 C  CA  . VAL B 1 419 ? -10.139 -24.533 6.736   1   20.257 ? 411  VAL B CA  1 
ATOM   7366 C  C   . VAL B 1 419 ? -10     -25.327 8.031   1   21.749 ? 411  VAL B C   1 
ATOM   7367 O  O   . VAL B 1 419 ? -9.141  -25.025 8.855   1   22.758 ? 411  VAL B O   1 
ATOM   7368 C  CB  . VAL B 1 419 ? -9.442  -25.281 5.573   1   21.077 ? 411  VAL B CB  1 
ATOM   7369 C  CG1 . VAL B 1 419 ? -9.829  -24.694 4.197   1   21.329 ? 411  VAL B CG1 1 
ATOM   7370 C  CG2 . VAL B 1 419 ? -7.932  -25.331 5.783   1   20.243 ? 411  VAL B CG2 1 
ATOM   7371 N  N   . PHE B 1 420 ? -10.818 -26.377 8.141   1   25.94  ? 412  PHE B N   1 
ATOM   7372 C  CA  . PHE B 1 420 ? -10.488 -27.53  8.962   1   28.177 ? 412  PHE B CA  1 
ATOM   7373 C  C   . PHE B 1 420 ? -9.554  -28.405 8.132   1   28.835 ? 412  PHE B C   1 
ATOM   7374 O  O   . PHE B 1 420 ? -9.938  -28.835 7.037   1   29.326 ? 412  PHE B O   1 
ATOM   7375 C  CB  . PHE B 1 420 ? -11.738 -28.376 9.217   1   31.716 ? 412  PHE B CB  1 
ATOM   7376 C  CG  . PHE B 1 420 ? -12.842 -27.899 10.144  1   37.97  ? 412  PHE B CG  1 
ATOM   7377 C  CD1 . PHE B 1 420 ? -13.253 -26.556 10.186  1   34.307 ? 412  PHE B CD1 1 
ATOM   7378 C  CD2 . PHE B 1 420 ? -13.528 -28.822 10.947  1   37.755 ? 412  PHE B CD2 1 
ATOM   7379 C  CE1 . PHE B 1 420 ? -14.319 -26.137 11.015  1   29.219 ? 412  PHE B CE1 1 
ATOM   7380 C  CE2 . PHE B 1 420 ? -14.615 -28.419 11.744  1   38.764 ? 412  PHE B CE2 1 
ATOM   7381 C  CZ  . PHE B 1 420 ? -15.009 -27.071 11.782  1   35.245 ? 412  PHE B CZ  1 
ATOM   7382 N  N   . VAL B 1 421 ? -8.309  -28.603 8.602   1   29.131 ? 413  VAL B N   1 
ATOM   7383 C  CA  . VAL B 1 421 ? -7.29   -29.272 7.798   1   32.159 ? 413  VAL B CA  1 
ATOM   7384 C  C   . VAL B 1 421 ? -7.674  -30.747 7.68    1   35.834 ? 413  VAL B C   1 
ATOM   7385 O  O   . VAL B 1 421 ? -7.878  -31.375 8.718   1   37.839 ? 413  VAL B O   1 
ATOM   7386 C  CB  . VAL B 1 421 ? -5.892  -29.105 8.429   1   32.516 ? 413  VAL B CB  1 
ATOM   7387 C  CG1 . VAL B 1 421 ? -4.843  -30.019 7.808   1   32.496 ? 413  VAL B CG1 1 
ATOM   7388 C  CG2 . VAL B 1 421 ? -5.406  -27.667 8.359   1   30.075 ? 413  VAL B CG2 1 
ATOM   7389 N  N   . PRO B 1 422 ? -7.814  -31.323 6.45    1   42.37  ? 414  PRO B N   1 
ATOM   7390 C  CA  . PRO B 1 422 ? -8.204  -32.734 6.289   1   40.374 ? 414  PRO B CA  1 
ATOM   7391 C  C   . PRO B 1 422 ? -7.305  -33.663 7.113   1   41.499 ? 414  PRO B C   1 
ATOM   7392 O  O   . PRO B 1 422 ? -6.082  -33.482 7.149   1   41.794 ? 414  PRO B O   1 
ATOM   7393 C  CB  . PRO B 1 422 ? -8.122  -32.989 4.757   1   38.073 ? 414  PRO B CB  1 
ATOM   7394 C  CG  . PRO B 1 422 ? -8.254  -31.613 4.129   1   42.272 ? 414  PRO B CG  1 
ATOM   7395 C  CD  . PRO B 1 422 ? -7.6    -30.662 5.142   1   42.192 ? 414  PRO B CD  1 
ATOM   7396 N  N   . ASP B 1 423 ? -7.949  -34.568 7.866   1   46.282 ? 415  ASP B N   1 
ATOM   7397 C  CA  . ASP B 1 423 ? -7.346  -35.643 8.655   1   60.152 ? 415  ASP B CA  1 
ATOM   7398 C  C   . ASP B 1 423 ? -6.711  -35.136 9.955   1   63.892 ? 415  ASP B C   1 
ATOM   7399 O  O   . ASP B 1 423 ? -6.159  -35.937 10.714  1   53.764 ? 415  ASP B O   1 
ATOM   7400 C  CB  . ASP B 1 423 ? -6.428  -36.551 7.835   1   69.436 ? 415  ASP B CB  1 
ATOM   7401 C  CG  . ASP B 1 423 ? -7.005  -37.067 6.524   1   73.477 ? 415  ASP B CG  1 
ATOM   7402 O  OD1 . ASP B 1 423 ? -8.133  -37.613 6.557   1   76.927 ? 415  ASP B OD1 1 
ATOM   7403 O  OD2 . ASP B 1 423 ? -6.333  -36.895 5.479   1   71.345 ? 415  ASP B OD2 1 
ATOM   7404 N  N   . ARG B 1 424 ? -6.799  -33.82  10.221  1   70.595 ? 416  ARG B N   1 
ATOM   7405 C  CA  . ARG B 1 424 ? -6.105  -33.172 11.328  1   74.834 ? 416  ARG B CA  1 
ATOM   7406 C  C   . ARG B 1 424 ? -7.049  -32.186 12.023  1   77.738 ? 416  ARG B C   1 
ATOM   7407 O  O   . ARG B 1 424 ? -6.596  -31.211 12.628  1   73.655 ? 416  ARG B O   1 
ATOM   7408 C  CB  . ARG B 1 424 ? -4.828  -32.437 10.881  1   71.844 ? 416  ARG B CB  1 
ATOM   7409 C  CG  . ARG B 1 424 ? -3.86   -33.089 9.899   1   70.094 ? 416  ARG B CG  1 
ATOM   7410 C  CD  . ARG B 1 424 ? -2.536  -32.371 9.644   1   73.811 ? 416  ARG B CD  1 
ATOM   7411 N  NE  . ARG B 1 424 ? -1.647  -32.411 10.813  1   70.461 ? 416  ARG B NE  1 
ATOM   7412 C  CZ  . ARG B 1 424 ? -0.39   -31.955 10.931  1   70.401 ? 416  ARG B CZ  1 
ATOM   7413 N  NH1 . ARG B 1 424 ? 0.216   -31.308 9.942   1   64.462 ? 416  ARG B NH1 1 
ATOM   7414 N  NH2 . ARG B 1 424 ? 0.245   -32.135 12.079  1   62.422 ? 416  ARG B NH2 1 
ATOM   7415 N  N   . SER B 1 425 ? -8.36   -32.452 11.937  1   73.588 ? 417  SER B N   1 
ATOM   7416 C  CA  . SER B 1 425 ? -9.4    -31.563 12.443  1   67.824 ? 417  SER B CA  1 
ATOM   7417 C  C   . SER B 1 425 ? -10.6   -32.371 12.937  1   67.326 ? 417  SER B C   1 
ATOM   7418 O  O   . SER B 1 425 ? -10.688 -33.574 12.68   1   63.631 ? 417  SER B O   1 
ATOM   7419 C  CB  . SER B 1 425 ? -9.787  -30.516 11.413  1   55.547 ? 417  SER B CB  1 
ATOM   7420 O  OG  . SER B 1 425 ? -10.173 -31.127 10.192  1   52.867 ? 417  SER B OG  1 
ATOM   7421 N  N   . ASP B 1 426 ? -11.505 -31.694 13.66   1   68.378 ? 418  ASP B N   1 
ATOM   7422 C  CA  . ASP B 1 426 ? -12.681 -32.31  14.255  1   72.9   ? 418  ASP B CA  1 
ATOM   7423 C  C   . ASP B 1 426 ? -13.922 -31.918 13.453  1   80.79  ? 418  ASP B C   1 
ATOM   7424 O  O   . ASP B 1 426 ? -14.492 -30.844 13.667  1   80.657 ? 418  ASP B O   1 
ATOM   7425 C  CB  . ASP B 1 426 ? -12.736 -32.038 15.753  1   67.202 ? 418  ASP B CB  1 
ATOM   7426 C  CG  . ASP B 1 426 ? -13.912 -32.618 16.528  1   61.824 ? 418  ASP B CG  1 
ATOM   7427 O  OD1 . ASP B 1 426 ? -14.746 -33.359 15.947  1   61.989 ? 418  ASP B OD1 1 
ATOM   7428 O  OD2 . ASP B 1 426 ? -13.992 -32.306 17.731  1   71.361 ? 418  ASP B OD2 1 
ATOM   7429 N  N   . GLY B 1 427 ? -14.354 -32.847 12.582  1   82.175 ? 419  GLY B N   1 
ATOM   7430 C  CA  . GLY B 1 427 ? -15.489 -32.695 11.676  1   75.342 ? 419  GLY B CA  1 
ATOM   7431 C  C   . GLY B 1 427 ? -16.83  -32.49  12.386  1   70.113 ? 419  GLY B C   1 
ATOM   7432 O  O   . GLY B 1 427 ? -17.798 -32.052 11.757  1   68.893 ? 419  GLY B O   1 
ATOM   7433 N  N   . ASN B 1 428 ? -16.88  -32.789 13.695  1   62.55  ? 420  ASN B N   1 
ATOM   7434 C  CA  . ASN B 1 428 ? -18.111 -32.659 14.46   1   67.351 ? 420  ASN B CA  1 
ATOM   7435 C  C   . ASN B 1 428 ? -18.318 -31.233 14.988  1   60.664 ? 420  ASN B C   1 
ATOM   7436 O  O   . ASN B 1 428 ? -19.395 -30.931 15.503  1   65.357 ? 420  ASN B O   1 
ATOM   7437 C  CB  . ASN B 1 428 ? -18.251 -33.792 15.476  1   73.008 ? 420  ASN B CB  1 
ATOM   7438 C  CG  . ASN B 1 428 ? -19.693 -34.178 15.703  1   76.985 ? 420  ASN B CG  1 
ATOM   7439 O  OD1 . ASN B 1 428 ? -20.198 -34.045 16.823  1   78.676 ? 420  ASN B OD1 1 
ATOM   7440 N  ND2 . ASN B 1 428 ? -20.368 -34.652 14.664  1   80.363 ? 420  ASN B ND2 1 
ATOM   7441 N  N   . LYS B 1 429 ? -17.301 -30.363 14.865  1   50.596 ? 421  LYS B N   1 
ATOM   7442 C  CA  . LYS B 1 429 ? -17.416 -28.975 15.296  1   42.394 ? 421  LYS B CA  1 
ATOM   7443 C  C   . LYS B 1 429 ? -18.244 -28.169 14.288  1   37.042 ? 421  LYS B C   1 
ATOM   7444 O  O   . LYS B 1 429 ? -18.144 -28.38  13.077  1   37.786 ? 421  LYS B O   1 
ATOM   7445 C  CB  . LYS B 1 429 ? -16.024 -28.362 15.519  1   46.464 ? 421  LYS B CB  1 
ATOM   7446 C  CG  . LYS B 1 429 ? -15.184 -28.888 16.7    1   46.359 ? 421  LYS B CG  1 
ATOM   7447 C  CD  . LYS B 1 429 ? -14.524 -27.811 17.547  1   51.444 ? 421  LYS B CD  1 
ATOM   7448 C  CE  . LYS B 1 429 ? -14.442 -28.144 19.023  1   54.4   ? 421  LYS B CE  1 
ATOM   7449 N  NZ  . LYS B 1 429 ? -13.214 -28.884 19.309  1   56.191 ? 421  LYS B NZ  1 
ATOM   7450 N  N   . ASN B 1 430 ? -19.058 -27.239 14.82   1   27.367 ? 422  ASN B N   1 
ATOM   7451 C  CA  . ASN B 1 430 ? -19.605 -26.086 14.088  1   24.536 ? 422  ASN B CA  1 
ATOM   7452 C  C   . ASN B 1 430 ? -18.493 -25.47  13.228  1   21.686 ? 422  ASN B C   1 
ATOM   7453 O  O   . ASN B 1 430 ? -17.32  -25.455 13.618  1   24.04  ? 422  ASN B O   1 
ATOM   7454 C  CB  . ASN B 1 430 ? -20.2   -25.076 15.084  1   22.055 ? 422  ASN B CB  1 
ATOM   7455 C  CG  . ASN B 1 430 ? -20.68  -23.805 14.421  1   22.971 ? 422  ASN B CG  1 
ATOM   7456 O  OD1 . ASN B 1 430 ? -21.854 -23.706 14.02   1   27.083 ? 422  ASN B OD1 1 
ATOM   7457 N  ND2 . ASN B 1 430 ? -19.814 -22.812 14.351  1   19.14  ? 422  ASN B ND2 1 
ATOM   7458 N  N   . VAL B 1 431 ? -18.858 -25.006 12.02   1   19.912 ? 423  VAL B N   1 
ATOM   7459 C  CA  . VAL B 1 431 ? -17.925 -24.56  10.99   1   20.895 ? 423  VAL B CA  1 
ATOM   7460 C  C   . VAL B 1 431 ? -16.968 -23.455 11.482  1   20.857 ? 423  VAL B C   1 
ATOM   7461 O  O   . VAL B 1 431 ? -15.847 -23.349 10.999  1   22.114 ? 423  VAL B O   1 
ATOM   7462 C  CB  . VAL B 1 431 ? -18.671 -24.171 9.68    1   21.602 ? 423  VAL B CB  1 
ATOM   7463 C  CG1 . VAL B 1 431 ? -19.477 -22.876 9.808   1   20.37  ? 423  VAL B CG1 1 
ATOM   7464 C  CG2 . VAL B 1 431 ? -17.716 -24.085 8.483   1   22.95  ? 423  VAL B CG2 1 
ATOM   7465 N  N   . PHE B 1 432 ? -17.427 -22.622 12.423  1   20.882 ? 424  PHE B N   1 
ATOM   7466 C  CA  . PHE B 1 432 ? -16.616 -21.494 12.885  1   18.63  ? 424  PHE B CA  1 
ATOM   7467 C  C   . PHE B 1 432 ? -15.63  -21.907 13.967  1   20.489 ? 424  PHE B C   1 
ATOM   7468 O  O   . PHE B 1 432 ? -14.818 -21.061 14.385  1   19.615 ? 424  PHE B O   1 
ATOM   7469 C  CB  . PHE B 1 432 ? -17.533 -20.39  13.428  1   17.711 ? 424  PHE B CB  1 
ATOM   7470 C  CG  . PHE B 1 432 ? -18.419 -19.766 12.351  1   18.718 ? 424  PHE B CG  1 
ATOM   7471 C  CD1 . PHE B 1 432 ? -17.864 -18.91  11.398  1   19.022 ? 424  PHE B CD1 1 
ATOM   7472 C  CD2 . PHE B 1 432 ? -19.802 -20.035 12.317  1   19.031 ? 424  PHE B CD2 1 
ATOM   7473 C  CE1 . PHE B 1 432 ? -18.656 -18.358 10.395  1   21.849 ? 424  PHE B CE1 1 
ATOM   7474 C  CE2 . PHE B 1 432 ? -20.603 -19.451 11.325  1   21.184 ? 424  PHE B CE2 1 
ATOM   7475 C  CZ  . PHE B 1 432 ? -20.031 -18.609 10.354  1   19.188 ? 424  PHE B CZ  1 
ATOM   7476 N  N   . GLN B 1 433 ? -15.702 -23.161 14.446  1   21.882 ? 425  GLN B N   1 
ATOM   7477 C  CA  . GLN B 1 433 ? -15.053 -23.529 15.711  1   23.124 ? 425  GLN B CA  1 
ATOM   7478 C  C   . GLN B 1 433 ? -13.894 -24.518 15.53   1   25.525 ? 425  GLN B C   1 
ATOM   7479 O  O   . GLN B 1 433 ? -13.075 -24.667 16.443  1   26.346 ? 425  GLN B O   1 
ATOM   7480 C  CB  . GLN B 1 433 ? -16.064 -24.096 16.712  1   21.804 ? 425  GLN B CB  1 
ATOM   7481 C  CG  . GLN B 1 433 ? -17.174 -23.107 17.043  1   22.671 ? 425  GLN B CG  1 
ATOM   7482 C  CD  . GLN B 1 433 ? -18.042 -23.543 18.201  1   26.699 ? 425  GLN B CD  1 
ATOM   7483 O  OE1 . GLN B 1 433 ? -17.917 -24.661 18.711  1   34.583 ? 425  GLN B OE1 1 
ATOM   7484 N  NE2 . GLN B 1 433 ? -18.968 -22.676 18.596  1   28.33  ? 425  GLN B NE2 1 
ATOM   7485 N  N   . GLY B 1 434 ? -13.789 -25.155 14.371  1   23.352 ? 426  GLY B N   1 
ATOM   7486 C  CA  . GLY B 1 434 ? -12.636 -26.051 14.204  1   29.715 ? 426  GLY B CA  1 
ATOM   7487 C  C   . GLY B 1 434 ? -11.556 -25.576 13.217  1   29.937 ? 426  GLY B C   1 
ATOM   7488 O  O   . GLY B 1 434 ? -10.889 -26.403 12.594  1   29.125 ? 426  GLY B O   1 
ATOM   7489 N  N   . LEU B 1 435 ? -11.407 -24.251 13.015  1   25.299 ? 427  LEU B N   1 
ATOM   7490 C  CA  . LEU B 1 435 ? -10.62  -23.767 11.879  1   25.013 ? 427  LEU B CA  1 
ATOM   7491 C  C   . LEU B 1 435 ? -9.149  -23.679 12.271  1   26.781 ? 427  LEU B C   1 
ATOM   7492 O  O   . LEU B 1 435 ? -8.76   -22.789 13.025  1   24.135 ? 427  LEU B O   1 
ATOM   7493 C  CB  . LEU B 1 435 ? -11.163 -22.445 11.318  1   23.092 ? 427  LEU B CB  1 
ATOM   7494 C  CG  . LEU B 1 435 ? -12.602 -22.5   10.776  1   22.196 ? 427  LEU B CG  1 
ATOM   7495 C  CD1 . LEU B 1 435 ? -13.218 -21.118 10.726  1   22.59  ? 427  LEU B CD1 1 
ATOM   7496 C  CD2 . LEU B 1 435 ? -12.613 -23.095 9.352   1   23.775 ? 427  LEU B CD2 1 
ATOM   7497 N  N   . ASN B 1 436 ? -8.34   -24.644 11.802  1   22.618 ? 428  ASN B N   1 
ATOM   7498 C  CA  . ASN B 1 436 ? -6.96   -24.818 12.237  1   21.683 ? 428  ASN B CA  1 
ATOM   7499 C  C   . ASN B 1 436 ? -5.983  -24.824 11.064  1   21.394 ? 428  ASN B C   1 
ATOM   7500 O  O   . ASN B 1 436 ? -4.825  -25.19  11.226  1   22.715 ? 428  ASN B O   1 
ATOM   7501 C  CB  . ASN B 1 436 ? -6.796  -26.078 13.087  1   22.031 ? 428  ASN B CB  1 
ATOM   7502 C  CG  . ASN B 1 436 ? -7.09   -27.349 12.298  1   27.08  ? 428  ASN B CG  1 
ATOM   7503 O  OD1 . ASN B 1 436 ? -7.62   -27.322 11.17   1   26.655 ? 428  ASN B OD1 1 
ATOM   7504 N  ND2 . ASN B 1 436 ? -6.737  -28.491 12.873  1   28.98  ? 428  ASN B ND2 1 
ATOM   7505 N  N   . GLY B 1 437 ? -6.435  -24.324 9.904   1   19.659 ? 429  GLY B N   1 
ATOM   7506 C  CA  . GLY B 1 437 ? -5.522  -24.159 8.794   1   18.97  ? 429  GLY B CA  1 
ATOM   7507 C  C   . GLY B 1 437 ? -6.003  -23.122 7.804   1   19.293 ? 429  GLY B C   1 
ATOM   7508 O  O   . GLY B 1 437 ? -7.09   -22.55  7.961   1   19.816 ? 429  GLY B O   1 
ATOM   7509 N  N   . LEU B 1 438 ? -5.151  -22.937 6.789   1   18.575 ? 430  LEU B N   1 
ATOM   7510 C  CA  . LEU B 1 438 ? -5.489  -22.113 5.631   1   17.544 ? 430  LEU B CA  1 
ATOM   7511 C  C   . LEU B 1 438 ? -5.275  -22.963 4.379   1   21.654 ? 430  LEU B C   1 
ATOM   7512 O  O   . LEU B 1 438 ? -4.39   -23.829 4.357   1   20.583 ? 430  LEU B O   1 
ATOM   7513 C  CB  . LEU B 1 438 ? -4.627  -20.862 5.532   1   19.528 ? 430  LEU B CB  1 
ATOM   7514 C  CG  . LEU B 1 438 ? -4.661  -19.951 6.766   1   19.517 ? 430  LEU B CG  1 
ATOM   7515 C  CD1 . LEU B 1 438 ? -3.586  -18.873 6.547   1   21.942 ? 430  LEU B CD1 1 
ATOM   7516 C  CD2 . LEU B 1 438 ? -6.042  -19.332 7.038   1   19.484 ? 430  LEU B CD2 1 
ATOM   7517 N  N   . ALA B 1 439 ? -6.038  -22.625 3.339   1   20.352 ? 431  ALA B N   1 
ATOM   7518 C  CA  . ALA B 1 439 ? -5.778  -23.187 2.021   1   22.308 ? 431  ALA B CA  1 
ATOM   7519 C  C   . ALA B 1 439 ? -5.58   -22.067 1.009   1   19.037 ? 431  ALA B C   1 
ATOM   7520 O  O   . ALA B 1 439 ? -6.265  -21.051 1.083   1   20.709 ? 431  ALA B O   1 
ATOM   7521 C  CB  . ALA B 1 439 ? -6.956  -24.06  1.591   1   25.784 ? 431  ALA B CB  1 
ATOM   7522 N  N   . HIS B 1 440 ? -4.646  -22.263 0.085   1   20.398 ? 432  HIS B N   1 
ATOM   7523 C  CA  . HIS B 1 440 ? -4.531  -21.401 -1.084  1   18.92  ? 432  HIS B CA  1 
ATOM   7524 C  C   . HIS B 1 440 ? -4.975  -22.232 -2.281  1   20.962 ? 432  HIS B C   1 
ATOM   7525 O  O   . HIS B 1 440 ? -4.235  -23.136 -2.695  1   21.628 ? 432  HIS B O   1 
ATOM   7526 C  CB  . HIS B 1 440 ? -3.095  -20.894 -1.299  1   21.004 ? 432  HIS B CB  1 
ATOM   7527 C  CG  . HIS B 1 440 ? -2.959  -19.931 -2.431  1   22.06  ? 432  HIS B CG  1 
ATOM   7528 N  ND1 . HIS B 1 440 ? -1.729  -19.422 -2.801  1   22.199 ? 432  HIS B ND1 1 
ATOM   7529 C  CD2 . HIS B 1 440 ? -3.862  -19.379 -3.271  1   20.868 ? 432  HIS B CD2 1 
ATOM   7530 C  CE1 . HIS B 1 440 ? -1.902  -18.555 -3.797  1   22.279 ? 432  HIS B CE1 1 
ATOM   7531 N  NE2 . HIS B 1 440 ? -3.188  -18.507 -4.084  1   20.913 ? 432  HIS B NE2 1 
ATOM   7532 N  N   . TYR B 1 441 ? -6.213  -21.996 -2.713  1   20.143 ? 433  TYR B N   1 
ATOM   7533 C  CA  . TYR B 1 441 ? -6.805  -22.654 -3.871  1   23.292 ? 433  TYR B CA  1 
ATOM   7534 C  C   . TYR B 1 441 ? -6.56   -21.787 -5.104  1   23.842 ? 433  TYR B C   1 
ATOM   7535 O  O   . TYR B 1 441 ? -6.708  -20.572 -5.07   1   22.878 ? 433  TYR B O   1 
ATOM   7536 C  CB  . TYR B 1 441 ? -8.293  -22.867 -3.615  1   21.204 ? 433  TYR B CB  1 
ATOM   7537 C  CG  . TYR B 1 441 ? -9.068  -23.279 -4.862  1   20.871 ? 433  TYR B CG  1 
ATOM   7538 C  CD1 . TYR B 1 441 ? -8.898  -24.578 -5.367  1   20.932 ? 433  TYR B CD1 1 
ATOM   7539 C  CD2 . TYR B 1 441 ? -9.912  -22.4   -5.543  1   23.67  ? 433  TYR B CD2 1 
ATOM   7540 C  CE1 . TYR B 1 441 ? -9.539  -24.98  -6.532  1   21.815 ? 433  TYR B CE1 1 
ATOM   7541 C  CE2 . TYR B 1 441 ? -10.589 -22.812 -6.697  1   22.436 ? 433  TYR B CE2 1 
ATOM   7542 C  CZ  . TYR B 1 441 ? -10.395 -24.105 -7.185  1   24.116 ? 433  TYR B CZ  1 
ATOM   7543 O  OH  . TYR B 1 441 ? -11.074 -24.523 -8.318  1   23.984 ? 433  TYR B OH  1 
ATOM   7544 N  N   . LYS B 1 442 ? -6.157  -22.441 -6.217  1   23.727 ? 434  LYS B N   1 
ATOM   7545 C  CA  . LYS B 1 442 ? -6.026  -21.756 -7.494  1   21.63  ? 434  LYS B CA  1 
ATOM   7546 C  C   . LYS B 1 442 ? -6.893  -22.479 -8.533  1   26.156 ? 434  LYS B C   1 
ATOM   7547 O  O   . LYS B 1 442 ? -6.574  -23.639 -8.891  1   25.881 ? 434  LYS B O   1 
ATOM   7548 C  CB  . LYS B 1 442 ? -4.566  -21.76  -7.963  1   23.94  ? 434  LYS B CB  1 
ATOM   7549 C  CG  . LYS B 1 442 ? -3.607  -20.865 -7.151  1   28.806 ? 434  LYS B CG  1 
ATOM   7550 C  CD  . LYS B 1 442 ? -2.175  -20.908 -7.674  1   29.477 ? 434  LYS B CD  1 
ATOM   7551 C  CE  . LYS B 1 442 ? -1.245  -20.085 -6.836  1   30.106 ? 434  LYS B CE  1 
ATOM   7552 N  NZ  . LYS B 1 442 ? 0.128   -19.974 -7.362  1   29.471 ? 434  LYS B NZ  1 
ATOM   7553 N  N   . ARG B 1 443 ? -7.947  -21.777 -9.005  1   23.293 ? 435  ARG B N   1 
ATOM   7554 C  CA  . ARG B 1 443 ? -8.881  -22.385 -9.953  1   23.958 ? 435  ARG B CA  1 
ATOM   7555 C  C   . ARG B 1 443 ? -8.147  -22.736 -11.249 1   26.505 ? 435  ARG B C   1 
ATOM   7556 O  O   . ARG B 1 443 ? -8.335  -23.852 -11.756 1   29.913 ? 435  ARG B O   1 
ATOM   7557 C  CB  . ARG B 1 443 ? -10.07  -21.463 -10.204 1   23.917 ? 435  ARG B CB  1 
ATOM   7558 C  CG  . ARG B 1 443 ? -11.063 -22.124 -11.164 1   25.243 ? 435  ARG B CG  1 
ATOM   7559 C  CD  . ARG B 1 443 ? -12.28  -21.253 -11.409 1   25.251 ? 435  ARG B CD  1 
ATOM   7560 N  NE  . ARG B 1 443 ? -11.989 -19.879 -11.853 1   26.408 ? 435  ARG B NE  1 
ATOM   7561 C  CZ  . ARG B 1 443 ? -11.56  -19.505 -13.056 1   27.045 ? 435  ARG B CZ  1 
ATOM   7562 N  NH1 . ARG B 1 443 ? -11.682 -20.335 -14.112 1   31.185 ? 435  ARG B NH1 1 
ATOM   7563 N  NH2 . ARG B 1 443 ? -11.115 -18.279 -13.263 1   26.065 ? 435  ARG B NH2 1 
ATOM   7564 N  N   . LYS B 1 444 ? -7.291  -21.827 -11.743 1   27.175 ? 436  LYS B N   1 
ATOM   7565 C  CA  . LYS B 1 444 ? -6.684  -22.002 -13.06  1   29.722 ? 436  LYS B CA  1 
ATOM   7566 C  C   . LYS B 1 444 ? -5.794  -23.241 -13.079 1   33.585 ? 436  LYS B C   1 
ATOM   7567 O  O   . LYS B 1 444 ? -5.932  -24.088 -13.963 1   34.112 ? 436  LYS B O   1 
ATOM   7568 C  CB  . LYS B 1 444 ? -6.005  -20.73  -13.585 1   28.687 ? 436  LYS B CB  1 
ATOM   7569 C  CG  . LYS B 1 444 ? -7.003  -19.652 -14.015 1   33.025 ? 436  LYS B CG  1 
ATOM   7570 C  CD  . LYS B 1 444 ? -6.424  -18.279 -14.358 1   34.565 ? 436  LYS B CD  1 
ATOM   7571 C  CE  . LYS B 1 444 ? -7.499  -17.379 -14.913 1   34.677 ? 436  LYS B CE  1 
ATOM   7572 N  NZ  . LYS B 1 444 ? -7.027  -15.995 -14.963 1   37.109 ? 436  LYS B NZ  1 
ATOM   7573 N  N   . GLU B 1 445 ? -4.921  -23.374 -12.075 1   29.368 ? 437  GLU B N   1 
ATOM   7574 C  CA  . GLU B 1 445 ? -4.008  -24.497 -11.936 1   29.882 ? 437  GLU B CA  1 
ATOM   7575 C  C   . GLU B 1 445 ? -4.695  -25.737 -11.342 1   29.769 ? 437  GLU B C   1 
ATOM   7576 O  O   . GLU B 1 445 ? -4.162  -26.842 -11.489 1   36.094 ? 437  GLU B O   1 
ATOM   7577 C  CB  . GLU B 1 445 ? -2.757  -24.144 -11.125 1   29.363 ? 437  GLU B CB  1 
ATOM   7578 C  CG  . GLU B 1 445 ? -1.842  -23.112 -11.788 1   33.14  ? 437  GLU B CG  1 
ATOM   7579 C  CD  . GLU B 1 445 ? -2.187  -21.644 -11.585 1   32.52  ? 437  GLU B CD  1 
ATOM   7580 O  OE1 . GLU B 1 445 ? -3.28   -21.298 -11.087 1   30.959 ? 437  GLU B OE1 1 
ATOM   7581 O  OE2 . GLU B 1 445 ? -1.323  -20.82  -11.947 1   37.179 ? 437  GLU B OE2 1 
ATOM   7582 N  N   . GLY B 1 446 ? -5.81   -25.562 -10.623 1   25.889 ? 438  GLY B N   1 
ATOM   7583 C  CA  . GLY B 1 446 ? -6.595  -26.625 -10     1   27.646 ? 438  GLY B CA  1 
ATOM   7584 C  C   . GLY B 1 446 ? -6.006  -27.159 -8.691  1   26.482 ? 438  GLY B C   1 
ATOM   7585 O  O   . GLY B 1 446 ? -6.498  -28.165 -8.163  1   28.122 ? 438  GLY B O   1 
ATOM   7586 N  N   . THR B 1 447 ? -5.021  -26.448 -8.125  1   29.639 ? 439  THR B N   1 
ATOM   7587 C  CA  . THR B 1 447 ? -4.259  -26.92  -6.966  1   26.61  ? 439  THR B CA  1 
ATOM   7588 C  C   . THR B 1 447 ? -4.781  -26.25  -5.689  1   25.616 ? 439  THR B C   1 
ATOM   7589 O  O   . THR B 1 447 ? -5.378  -25.181 -5.759  1   25.512 ? 439  THR B O   1 
ATOM   7590 C  CB  . THR B 1 447 ? -2.781  -26.583 -7.122  1   31.035 ? 439  THR B CB  1 
ATOM   7591 O  OG1 . THR B 1 447 ? -2.672  -25.182 -7.412  1   31.29  ? 439  THR B OG1 1 
ATOM   7592 C  CG2 . THR B 1 447 ? -2.12   -27.383 -8.239  1   30.976 ? 439  THR B CG2 1 
ATOM   7593 N  N   . THR B 1 448 ? -4.613  -26.963 -4.572  1   28.716 ? 440  THR B N   1 
ATOM   7594 C  CA  . THR B 1 448 ? -4.828  -26.417 -3.24   1   24.215 ? 440  THR B CA  1 
ATOM   7595 C  C   . THR B 1 448 ? -3.578  -26.715 -2.425  1   25.161 ? 440  THR B C   1 
ATOM   7596 O  O   . THR B 1 448 ? -3.132  -27.862 -2.34   1   25.607 ? 440  THR B O   1 
ATOM   7597 C  CB  . THR B 1 448 ? -6.073  -27.006 -2.576  1   23.388 ? 440  THR B CB  1 
ATOM   7598 O  OG1 . THR B 1 448 ? -7.189  -26.831 -3.458  1   26.329 ? 440  THR B OG1 1 
ATOM   7599 C  CG2 . THR B 1 448 ? -6.377  -26.301 -1.258  1   25.506 ? 440  THR B CG2 1 
ATOM   7600 N  N   . GLU B 1 449 ? -3.024  -25.664 -1.813  1   23.067 ? 441  GLU B N   1 
ATOM   7601 C  CA  . GLU B 1 449 ? -1.888  -25.781 -0.906  1   22.127 ? 441  GLU B CA  1 
ATOM   7602 C  C   . GLU B 1 449 ? -2.401  -25.496 0.504   1   24.979 ? 441  GLU B C   1 
ATOM   7603 O  O   . GLU B 1 449 ? -3.364  -24.73  0.665   1   24.82  ? 441  GLU B O   1 
ATOM   7604 C  CB  . GLU B 1 449 ? -0.75   -24.827 -1.269  1   26.845 ? 441  GLU B CB  1 
ATOM   7605 C  CG  . GLU B 1 449 ? -0.288  -25.052 -2.71   1   29.868 ? 441  GLU B CG  1 
ATOM   7606 C  CD  . GLU B 1 449 ? 0.498   -23.885 -3.276  1   29.489 ? 441  GLU B CD  1 
ATOM   7607 O  OE1 . GLU B 1 449 ? 1.705   -23.848 -3.013  1   34.965 ? 441  GLU B OE1 1 
ATOM   7608 O  OE2 . GLU B 1 449 ? -0.085  -23.026 -3.961  1   37.293 ? 441  GLU B OE2 1 
ATOM   7609 N  N   . TRP B 1 450 ? -1.764  -26.152 1.487   1   24.732 ? 442  TRP B N   1 
ATOM   7610 C  CA  . TRP B 1 450 ? -2.314  -26.169 2.841   1   27.408 ? 442  TRP B CA  1 
ATOM   7611 C  C   . TRP B 1 450 ? -1.292  -25.642 3.848   1   25.284 ? 442  TRP B C   1 
ATOM   7612 O  O   . TRP B 1 450 ? -0.125  -26.022 3.819   1   25.87  ? 442  TRP B O   1 
ATOM   7613 C  CB  . TRP B 1 450 ? -2.731  -27.598 3.204   1   27.389 ? 442  TRP B CB  1 
ATOM   7614 C  CG  . TRP B 1 450 ? -3.712  -28.205 2.239   1   24.408 ? 442  TRP B CG  1 
ATOM   7615 C  CD1 . TRP B 1 450 ? -3.405  -28.941 1.122   1   27.859 ? 442  TRP B CD1 1 
ATOM   7616 C  CD2 . TRP B 1 450 ? -5.156  -28.176 2.324   1   26.314 ? 442  TRP B CD2 1 
ATOM   7617 N  NE1 . TRP B 1 450 ? -4.568  -29.317 0.482   1   26.277 ? 442  TRP B NE1 1 
ATOM   7618 C  CE2 . TRP B 1 450 ? -5.653  -28.877 1.196   1   25.641 ? 442  TRP B CE2 1 
ATOM   7619 C  CE3 . TRP B 1 450 ? -6.082  -27.625 3.23    1   25.479 ? 442  TRP B CE3 1 
ATOM   7620 C  CZ2 . TRP B 1 450 ? -7.022  -29.067 0.97    1   27.34  ? 442  TRP B CZ2 1 
ATOM   7621 C  CZ3 . TRP B 1 450 ? -7.43   -27.805 2.999   1   29.275 ? 442  TRP B CZ3 1 
ATOM   7622 C  CH2 . TRP B 1 450 ? -7.902  -28.518 1.883   1   29.457 ? 442  TRP B CH2 1 
ATOM   7623 N  N   . TYR B 1 451 ? -1.774  -24.76  4.75    1   24.806 ? 443  TYR B N   1 
ATOM   7624 C  CA  . TYR B 1 451 ? -0.998  -24.31  5.896   1   23.862 ? 443  TYR B CA  1 
ATOM   7625 C  C   . TYR B 1 451 ? -1.681  -24.828 7.16    1   21.709 ? 443  TYR B C   1 
ATOM   7626 O  O   . TYR B 1 451 ? -2.88   -24.601 7.35    1   22.115 ? 443  TYR B O   1 
ATOM   7627 C  CB  . TYR B 1 451 ? -0.906  -22.78  5.947   1   22.948 ? 443  TYR B CB  1 
ATOM   7628 C  CG  . TYR B 1 451 ? -0.144  -22.337 7.2     1   22.906 ? 443  TYR B CG  1 
ATOM   7629 C  CD1 . TYR B 1 451 ? 1.249   -22.432 7.268   1   22.166 ? 443  TYR B CD1 1 
ATOM   7630 C  CD2 . TYR B 1 451 ? -0.824  -21.869 8.341   1   21.937 ? 443  TYR B CD2 1 
ATOM   7631 C  CE1 . TYR B 1 451 ? 1.948   -22.046 8.411   1   23.024 ? 443  TYR B CE1 1 
ATOM   7632 C  CE2 . TYR B 1 451 ? -0.13   -21.467 9.486   1   22.084 ? 443  TYR B CE2 1 
ATOM   7633 C  CZ  . TYR B 1 451 ? 1.254   -21.573 9.514   1   21.524 ? 443  TYR B CZ  1 
ATOM   7634 O  OH  . TYR B 1 451 ? 1.94    -21.227 10.656  1   22.889 ? 443  TYR B OH  1 
ATOM   7635 N  N   . TYR B 1 452 ? -0.906  -25.522 8.017   1   21.843 ? 444  TYR B N   1 
ATOM   7636 C  CA  . TYR B 1 452 ? -1.433  -26.014 9.283   1   23.563 ? 444  TYR B CA  1 
ATOM   7637 C  C   . TYR B 1 452 ? -1.039  -25.067 10.419  1   21.904 ? 444  TYR B C   1 
ATOM   7638 O  O   . TYR B 1 452 ? 0.136   -24.766 10.59   1   23.844 ? 444  TYR B O   1 
ATOM   7639 C  CB  . TYR B 1 452 ? -0.891  -27.419 9.586   1   23.564 ? 444  TYR B CB  1 
ATOM   7640 C  CG  . TYR B 1 452 ? -1.276  -28.011 10.941  1   23.527 ? 444  TYR B CG  1 
ATOM   7641 C  CD1 . TYR B 1 452 ? -2.608  -28.156 11.328  1   25.533 ? 444  TYR B CD1 1 
ATOM   7642 C  CD2 . TYR B 1 452 ? -0.289  -28.467 11.827  1   25.866 ? 444  TYR B CD2 1 
ATOM   7643 C  CE1 . TYR B 1 452 ? -2.951  -28.733 12.55   1   28.87  ? 444  TYR B CE1 1 
ATOM   7644 C  CE2 . TYR B 1 452 ? -0.621  -29.06  13.043  1   23.086 ? 444  TYR B CE2 1 
ATOM   7645 C  CZ  . TYR B 1 452 ? -1.953  -29.179 13.411  1   25.888 ? 444  TYR B CZ  1 
ATOM   7646 O  OH  . TYR B 1 452 ? -2.325  -29.725 14.618  1   27.91  ? 444  TYR B OH  1 
ATOM   7647 N  N   . ALA B 1 453 ? -2.031  -24.63  11.217  1   22.057 ? 445  ALA B N   1 
ATOM   7648 C  CA  . ALA B 1 453 ? -1.749  -23.603 12.233  1   25.678 ? 445  ALA B CA  1 
ATOM   7649 C  C   . ALA B 1 453 ? -0.841  -24.127 13.347  1   25.905 ? 445  ALA B C   1 
ATOM   7650 O  O   . ALA B 1 453 ? -0.148  -23.35  14.016  1   24.427 ? 445  ALA B O   1 
ATOM   7651 C  CB  . ALA B 1 453 ? -3.037  -23.046 12.808  1   26.356 ? 445  ALA B CB  1 
ATOM   7652 N  N   . GLY B 1 454 ? -0.891  -25.44  13.588  1   25.517 ? 446  GLY B N   1 
ATOM   7653 C  CA  . GLY B 1 454 ? -0.094  -26.079 14.63   1   24.877 ? 446  GLY B CA  1 
ATOM   7654 C  C   . GLY B 1 454 ? -0.992  -26.79  15.639  1   25.35  ? 446  GLY B C   1 
ATOM   7655 O  O   . GLY B 1 454 ? -2.191  -26.537 15.736  1   26.2   ? 446  GLY B O   1 
ATOM   7656 N  N   . ASP B 1 455 ? -0.387  -27.704 16.423  1   28.047 ? 447  ASP B N   1 
ATOM   7657 C  CA  . ASP B 1 455 ? -1.123  -28.371 17.489  1   27.396 ? 447  ASP B CA  1 
ATOM   7658 C  C   . ASP B 1 455 ? -1.558  -27.345 18.532  1   27.148 ? 447  ASP B C   1 
ATOM   7659 O  O   . ASP B 1 455 ? -0.781  -26.438 18.848  1   29.168 ? 447  ASP B O   1 
ATOM   7660 C  CB  . ASP B 1 455 ? -0.256  -29.402 18.189  1   29.442 ? 447  ASP B CB  1 
ATOM   7661 C  CG  . ASP B 1 455 ? 0.086   -30.653 17.394  1   37.232 ? 447  ASP B CG  1 
ATOM   7662 O  OD1 . ASP B 1 455 ? -0.334  -30.771 16.216  1   35.734 ? 447  ASP B OD1 1 
ATOM   7663 O  OD2 . ASP B 1 455 ? 0.761   -31.514 17.978  1   32.416 ? 447  ASP B OD2 1 
ATOM   7664 N  N   . ASN B 1 456 ? -2.8    -27.501 19.006  1   29.043 ? 448  ASN B N   1 
ATOM   7665 C  CA  . ASN B 1 456 ? -3.426  -26.66  20.026  1   30.053 ? 448  ASN B CA  1 
ATOM   7666 C  C   . ASN B 1 456 ? -3.473  -25.201 19.558  1   31.953 ? 448  ASN B C   1 
ATOM   7667 O  O   . ASN B 1 456 ? -3.317  -24.272 20.368  1   27.928 ? 448  ASN B O   1 
ATOM   7668 C  CB  . ASN B 1 456 ? -2.755  -26.762 21.401  1   34.44  ? 448  ASN B CB  1 
ATOM   7669 C  CG  . ASN B 1 456 ? -2.728  -28.181 21.915  1   42.51  ? 448  ASN B CG  1 
ATOM   7670 O  OD1 . ASN B 1 456 ? -1.647  -28.776 22.018  1   45.014 ? 448  ASN B OD1 1 
ATOM   7671 N  ND2 . ASN B 1 456 ? -3.896  -28.74  22.193  1   43.986 ? 448  ASN B ND2 1 
ATOM   7672 N  N   . CYS B 1 457 ? -3.679  -25.036 18.244  1   26.515 ? 449  CYS B N   1 
ATOM   7673 C  CA  . CYS B 1 457 ? -3.826  -23.734 17.619  1   24.876 ? 449  CYS B CA  1 
ATOM   7674 C  C   . CYS B 1 457 ? -5.122  -23.653 16.82   1   24.892 ? 449  CYS B C   1 
ATOM   7675 O  O   . CYS B 1 457 ? -5.595  -24.638 16.248  1   25.981 ? 449  CYS B O   1 
ATOM   7676 C  CB  . CYS B 1 457 ? -2.659  -23.413 16.701  1   25.177 ? 449  CYS B CB  1 
ATOM   7677 S  SG  . CYS B 1 457 ? -1.064  -23.265 17.557  1   25.945 ? 449  CYS B SG  1 
ATOM   7678 N  N   . LEU B 1 458 ? -5.657  -22.431 16.742  1   21.9   ? 450  LEU B N   1 
ATOM   7679 C  CA  . LEU B 1 458 ? -6.637  -22.096 15.731  1   22.045 ? 450  LEU B CA  1 
ATOM   7680 C  C   . LEU B 1 458 ? -6.041  -20.987 14.892  1   21.619 ? 450  LEU B C   1 
ATOM   7681 O  O   . LEU B 1 458 ? -5.064  -20.343 15.302  1   23.07  ? 450  LEU B O   1 
ATOM   7682 C  CB  . LEU B 1 458 ? -7.991  -21.717 16.34   1   23.703 ? 450  LEU B CB  1 
ATOM   7683 C  CG  . LEU B 1 458 ? -8.719  -22.805 17.135  1   27.926 ? 450  LEU B CG  1 
ATOM   7684 C  CD1 . LEU B 1 458 ? -9.891  -22.138 17.871  1   32.66  ? 450  LEU B CD1 1 
ATOM   7685 C  CD2 . LEU B 1 458 ? -9.191  -23.917 16.208  1   26.174 ? 450  LEU B CD2 1 
ATOM   7686 N  N   . ILE B 1 459 ? -6.617  -20.796 13.701  1   19.786 ? 451  ILE B N   1 
ATOM   7687 C  CA  . ILE B 1 459 ? -6.194  -19.693 12.85   1   17.891 ? 451  ILE B CA  1 
ATOM   7688 C  C   . ILE B 1 459 ? -7.455  -19.059 12.254  1   18.423 ? 451  ILE B C   1 
ATOM   7689 O  O   . ILE B 1 459 ? -8.469  -19.725 12.018  1   20.377 ? 451  ILE B O   1 
ATOM   7690 C  CB  . ILE B 1 459 ? -5.167  -20.154 11.804  1   19.076 ? 451  ILE B CB  1 
ATOM   7691 C  CG1 . ILE B 1 459 ? -4.517  -19.034 11.006  1   19.621 ? 451  ILE B CG1 1 
ATOM   7692 C  CG2 . ILE B 1 459 ? -5.804  -21.181 10.862  1   19.394 ? 451  ILE B CG2 1 
ATOM   7693 C  CD1 . ILE B 1 459 ? -3.211  -19.448 10.316  1   19.168 ? 451  ILE B CD1 1 
ATOM   7694 N  N   . GLN B 1 460 ? -7.41   -17.73  12.099  1   18.161 ? 452  GLN B N   1 
ATOM   7695 C  CA  . GLN B 1 460 ? -8.568  -16.951 11.653  1   17.389 ? 452  GLN B CA  1 
ATOM   7696 C  C   . GLN B 1 460 ? -8.412  -16.568 10.175  1   16.163 ? 452  GLN B C   1 
ATOM   7697 O  O   . GLN B 1 460 ? -7.49   -17.03  9.484   1   17.463 ? 452  GLN B O   1 
ATOM   7698 C  CB  . GLN B 1 460 ? -8.675  -15.756 12.616  1   15.834 ? 452  GLN B CB  1 
ATOM   7699 C  CG  . GLN B 1 460 ? -9.155  -16.176 14.013  1   18.154 ? 452  GLN B CG  1 
ATOM   7700 C  CD  . GLN B 1 460 ? -8.861  -15.141 15.069  1   17.828 ? 452  GLN B CD  1 
ATOM   7701 O  OE1 . GLN B 1 460 ? -9.223  -13.961 14.926  1   17.963 ? 452  GLN B OE1 1 
ATOM   7702 N  NE2 . GLN B 1 460 ? -8.106  -15.543 16.088  1   16.715 ? 452  GLN B NE2 1 
ATOM   7703 N  N   . GLU B 1 461 ? -9.313  -15.709 9.691   1   16.491 ? 453  GLU B N   1 
ATOM   7704 C  CA  . GLU B 1 461 ? -9.455  -15.451 8.254   1   16.252 ? 453  GLU B CA  1 
ATOM   7705 C  C   . GLU B 1 461 ? -8.139  -14.901 7.685   1   17.964 ? 453  GLU B C   1 
ATOM   7706 O  O   . GLU B 1 461 ? -7.526  -14.004 8.279   1   17.815 ? 453  GLU B O   1 
ATOM   7707 C  CB  . GLU B 1 461 ? -10.514 -14.376 8.078   1   15.855 ? 453  GLU B CB  1 
ATOM   7708 C  CG  . GLU B 1 461 ? -10.618 -13.878 6.628   1   15.237 ? 453  GLU B CG  1 
ATOM   7709 C  CD  . GLU B 1 461 ? -11.5   -12.667 6.597   1   17.307 ? 453  GLU B CD  1 
ATOM   7710 O  OE1 . GLU B 1 461 ? -11.197 -11.725 7.339   1   17.562 ? 453  GLU B OE1 1 
ATOM   7711 O  OE2 . GLU B 1 461 ? -12.458 -12.559 5.803   1   16.135 ? 453  GLU B OE2 1 
ATOM   7712 N  N   . PRO B 1 462 ? -7.666  -15.411 6.53    1   16.799 ? 454  PRO B N   1 
ATOM   7713 C  CA  . PRO B 1 462 ? -6.458  -14.877 5.889   1   17.274 ? 454  PRO B CA  1 
ATOM   7714 C  C   . PRO B 1 462 ? -6.728  -13.609 5.093   1   17.245 ? 454  PRO B C   1 
ATOM   7715 O  O   . PRO B 1 462 ? -7.831  -13.417 4.552   1   19.059 ? 454  PRO B O   1 
ATOM   7716 C  CB  . PRO B 1 462 ? -6.031  -16.027 4.975   1   16.169 ? 454  PRO B CB  1 
ATOM   7717 C  CG  . PRO B 1 462 ? -7.393  -16.645 4.553   1   16.832 ? 454  PRO B CG  1 
ATOM   7718 C  CD  . PRO B 1 462 ? -8.312  -16.52  5.777   1   18.185 ? 454  PRO B CD  1 
ATOM   7719 N  N   . VAL B 1 463 ? -5.692  -12.767 5.011   1   17.025 ? 455  VAL B N   1 
ATOM   7720 C  CA  . VAL B 1 463 ? -5.66   -11.647 4.091   1   16.142 ? 455  VAL B CA  1 
ATOM   7721 C  C   . VAL B 1 463 ? -4.392  -11.768 3.262   1   16.839 ? 455  VAL B C   1 
ATOM   7722 O  O   . VAL B 1 463 ? -3.379  -12.27  3.735   1   16.663 ? 455  VAL B O   1 
ATOM   7723 C  CB  . VAL B 1 463 ? -5.749  -10.272 4.801   1   16.955 ? 455  VAL B CB  1 
ATOM   7724 C  CG1 . VAL B 1 463 ? -7.063  -10.154 5.611   1   17.399 ? 455  VAL B CG1 1 
ATOM   7725 C  CG2 . VAL B 1 463 ? -4.53   -9.98   5.69    1   19.094 ? 455  VAL B CG2 1 
ATOM   7726 N  N   . PHE B 1 464 ? -4.449  -11.16  2.062   1   20.004 ? 456  PHE B N   1 
ATOM   7727 C  CA  . PHE B 1 464 ? -3.319  -11.221 1.148   1   18.476 ? 456  PHE B CA  1 
ATOM   7728 C  C   . PHE B 1 464 ? -2.781  -9.831  0.814   1   17.671 ? 456  PHE B C   1 
ATOM   7729 O  O   . PHE B 1 464 ? -3.519  -8.847  0.663   1   17.623 ? 456  PHE B O   1 
ATOM   7730 C  CB  . PHE B 1 464 ? -3.86   -11.904 -0.119  1   17.532 ? 456  PHE B CB  1 
ATOM   7731 C  CG  . PHE B 1 464 ? -2.887  -11.869 -1.297  1   18.502 ? 456  PHE B CG  1 
ATOM   7732 C  CD1 . PHE B 1 464 ? -1.782  -12.739 -1.33   1   19.225 ? 456  PHE B CD1 1 
ATOM   7733 C  CD2 . PHE B 1 464 ? -3.087  -10.94  -2.323  1   17.81  ? 456  PHE B CD2 1 
ATOM   7734 C  CE1 . PHE B 1 464 ? -0.894  -12.716 -2.416  1   19.401 ? 456  PHE B CE1 1 
ATOM   7735 C  CE2 . PHE B 1 464 ? -2.184  -10.91  -3.402  1   21.644 ? 456  PHE B CE2 1 
ATOM   7736 C  CZ  . PHE B 1 464 ? -1.105  -11.803 -3.432  1   19.31  ? 456  PHE B CZ  1 
ATOM   7737 N  N   . SER B 1 465 ? -1.445  -9.765  0.705   1   17.962 ? 457  SER B N   1 
ATOM   7738 C  CA  . SER B 1 465 ? -0.773  -8.56   0.232   1   18.158 ? 457  SER B CA  1 
ATOM   7739 C  C   . SER B 1 465 ? 0.122   -8.962  -0.947  1   20.496 ? 457  SER B C   1 
ATOM   7740 O  O   . SER B 1 465 ? 1.006   -9.8    -0.756  1   20.333 ? 457  SER B O   1 
ATOM   7741 C  CB  . SER B 1 465 ? 0.077   -7.926  1.353   1   18.567 ? 457  SER B CB  1 
ATOM   7742 O  OG  . SER B 1 465 ? 0.766   -6.773  0.836   1   23.617 ? 457  SER B OG  1 
ATOM   7743 N  N   . PRO B 1 466 ? -0.043  -8.37   -2.153  1   18.552 ? 458  PRO B N   1 
ATOM   7744 C  CA  . PRO B 1 466 ? 0.81    -8.775  -3.284  1   20.953 ? 458  PRO B CA  1 
ATOM   7745 C  C   . PRO B 1 466 ? 2.274   -8.434  -3.041  1   22.099 ? 458  PRO B C   1 
ATOM   7746 O  O   . PRO B 1 466 ? 2.578   -7.417  -2.423  1   21.164 ? 458  PRO B O   1 
ATOM   7747 C  CB  . PRO B 1 466 ? 0.224   -8.073  -4.514  1   23.993 ? 458  PRO B CB  1 
ATOM   7748 C  CG  . PRO B 1 466 ? -0.548  -6.933  -3.927  1   26.211 ? 458  PRO B CG  1 
ATOM   7749 C  CD  . PRO B 1 466 ? -1.009  -7.305  -2.501  1   21.004 ? 458  PRO B CD  1 
ATOM   7750 N  N   . ARG B 1 467 ? 3.179   -9.268  -3.574  1   20.523 ? 459  ARG B N   1 
ATOM   7751 C  CA  . ARG B 1 467 ? 4.595   -9.008  -3.371  1   20.356 ? 459  ARG B CA  1 
ATOM   7752 C  C   . ARG B 1 467 ? 5.007   -7.616  -3.852  1   22.774 ? 459  ARG B C   1 
ATOM   7753 O  O   . ARG B 1 467 ? 5.899   -7.02   -3.256  1   24.182 ? 459  ARG B O   1 
ATOM   7754 C  CB  . ARG B 1 467 ? 5.354   -10.067 -4.176  1   20.341 ? 459  ARG B CB  1 
ATOM   7755 C  CG  . ARG B 1 467 ? 6.807   -10.176 -3.743  1   22.052 ? 459  ARG B CG  1 
ATOM   7756 C  CD  . ARG B 1 467 ? 7.507   -11.308 -4.51   1   21.356 ? 459  ARG B CD  1 
ATOM   7757 N  NE  . ARG B 1 467 ? 6.856   -12.614 -4.347  1   24.02  ? 459  ARG B NE  1 
ATOM   7758 C  CZ  . ARG B 1 467 ? 6.84    -13.35  -3.241  1   23     ? 459  ARG B CZ  1 
ATOM   7759 N  NH1 . ARG B 1 467 ? 7.695   -13.082 -2.261  1   24.649 ? 459  ARG B NH1 1 
ATOM   7760 N  NH2 . ARG B 1 467 ? 6.034   -14.406 -3.152  1   21.898 ? 459  ARG B NH2 1 
ATOM   7761 N  N   . SER B 1 468 ? 4.41    -7.172  -4.964  1   23.599 ? 460  SER B N   1 
ATOM   7762 C  CA  . SER B 1 468 ? 4.515   -5.84   -5.545  1   27.307 ? 460  SER B CA  1 
ATOM   7763 C  C   . SER B 1 468 ? 3.241   -5.597  -6.358  1   26.548 ? 460  SER B C   1 
ATOM   7764 O  O   . SER B 1 468 ? 2.484   -6.539  -6.603  1   27.483 ? 460  SER B O   1 
ATOM   7765 C  CB  . SER B 1 468 ? 5.764   -5.73   -6.43   1   27.163 ? 460  SER B CB  1 
ATOM   7766 O  OG  . SER B 1 468 ? 5.625   -6.676  -7.49   1   28.607 ? 460  SER B OG  1 
ATOM   7767 N  N   . LYS B 1 469 ? 3.025   -4.344  -6.795  1   29.44  ? 461  LYS B N   1 
ATOM   7768 C  CA  . LYS B 1 469 ? 1.764   -3.971  -7.432  1   34.734 ? 461  LYS B CA  1 
ATOM   7769 C  C   . LYS B 1 469 ? 1.513   -4.776  -8.711  1   35.445 ? 461  LYS B C   1 
ATOM   7770 O  O   . LYS B 1 469 ? 0.346   -5.057  -9.011  1   32.478 ? 461  LYS B O   1 
ATOM   7771 C  CB  . LYS B 1 469 ? 1.538   -2.456  -7.513  1   43.526 ? 461  LYS B CB  1 
ATOM   7772 C  CG  . LYS B 1 469 ? 2.378   -1.601  -8.462  1   56.326 ? 461  LYS B CG  1 
ATOM   7773 C  CD  . LYS B 1 469 ? 2.476   -0.148  -7.98   1   67.127 ? 461  LYS B CD  1 
ATOM   7774 C  CE  . LYS B 1 469 ? 2.179   0.946   -8.976  1   73.827 ? 461  LYS B CE  1 
ATOM   7775 N  NZ  . LYS B 1 469 ? 2.922   0.838   -10.237 1   74.521 ? 461  LYS B NZ  1 
ATOM   7776 N  N   . ASP B 1 470 ? 2.588   -5.203  -9.407  1   32.199 ? 462  ASP B N   1 
ATOM   7777 C  CA  . ASP B 1 470 ? 2.431   -5.972  -10.636 1   32.83  ? 462  ASP B CA  1 
ATOM   7778 C  C   . ASP B 1 470 ? 2.893   -7.416  -10.491 1   33.774 ? 462  ASP B C   1 
ATOM   7779 O  O   . ASP B 1 470 ? 3.063   -8.102  -11.502 1   32.97  ? 462  ASP B O   1 
ATOM   7780 C  CB  . ASP B 1 470 ? 3.087   -5.298  -11.836 1   44.196 ? 462  ASP B CB  1 
ATOM   7781 C  CG  . ASP B 1 470 ? 2.669   -3.859  -12.122 1   53.557 ? 462  ASP B CG  1 
ATOM   7782 O  OD1 . ASP B 1 470 ? 1.442   -3.589  -12.222 1   50.679 ? 462  ASP B OD1 1 
ATOM   7783 O  OD2 . ASP B 1 470 ? 3.579   -3.017  -12.263 1   60.027 ? 462  ASP B OD2 1 
ATOM   7784 N  N   . ALA B 1 471 ? 2.998   -7.928  -9.256  1   26.841 ? 463  ALA B N   1 
ATOM   7785 C  CA  . ALA B 1 471 ? 3.181   -9.354  -9.035  1   24.418 ? 463  ALA B CA  1 
ATOM   7786 C  C   . ALA B 1 471 ? 2.028   -10.132 -9.691  1   24.018 ? 463  ALA B C   1 
ATOM   7787 O  O   . ALA B 1 471 ? 0.906   -9.622  -9.767  1   27.979 ? 463  ALA B O   1 
ATOM   7788 C  CB  . ALA B 1 471 ? 3.278   -9.67   -7.548  1   24.717 ? 463  ALA B CB  1 
ATOM   7789 N  N   . PRO B 1 472 ? 2.242   -11.404 -10.122 1   26.204 ? 464  PRO B N   1 
ATOM   7790 C  CA  . PRO B 1 472 ? 1.143   -12.244 -10.604 1   24.47  ? 464  PRO B CA  1 
ATOM   7791 C  C   . PRO B 1 472 ? 0.062   -12.432 -9.535  1   25.391 ? 464  PRO B C   1 
ATOM   7792 O  O   . PRO B 1 472 ? 0.326   -12.276 -8.333  1   23.852 ? 464  PRO B O   1 
ATOM   7793 C  CB  . PRO B 1 472 ? 1.815   -13.588 -10.948 1   28.351 ? 464  PRO B CB  1 
ATOM   7794 C  CG  . PRO B 1 472 ? 3.287   -13.223 -11.171 1   31.055 ? 464  PRO B CG  1 
ATOM   7795 C  CD  . PRO B 1 472 ? 3.553   -12.093 -10.186 1   28.302 ? 464  PRO B CD  1 
ATOM   7796 N  N   . GLU B 1 473 ? -1.138  -12.757 -9.989  1   23.045 ? 465  GLU B N   1 
ATOM   7797 C  CA  . GLU B 1 473 ? -2.242  -13.039 -9.077  1   24.598 ? 465  GLU B CA  1 
ATOM   7798 C  C   . GLU B 1 473 ? -1.833  -14.045 -7.995  1   24.976 ? 465  GLU B C   1 
ATOM   7799 O  O   . GLU B 1 473 ? -1.312  -15.128 -8.267  1   24.051 ? 465  GLU B O   1 
ATOM   7800 C  CB  . GLU B 1 473 ? -3.405  -13.629 -9.869  1   21.96  ? 465  GLU B CB  1 
ATOM   7801 C  CG  . GLU B 1 473 ? -4.621  -13.872 -8.975  1   23.527 ? 465  GLU B CG  1 
ATOM   7802 C  CD  . GLU B 1 473 ? -5.881  -14.32  -9.66   1   25.053 ? 465  GLU B CD  1 
ATOM   7803 O  OE1 . GLU B 1 473 ? -5.941  -14.413 -10.917 1   25.85  ? 465  GLU B OE1 1 
ATOM   7804 O  OE2 . GLU B 1 473 ? -6.839  -14.564 -8.908  1   23.185 ? 465  GLU B OE2 1 
ATOM   7805 N  N   . GLY B 1 474 ? -2.111  -13.673 -6.723  1   20.892 ? 466  GLY B N   1 
ATOM   7806 C  CA  . GLY B 1 474 ? -1.878  -14.574 -5.608  1   23.4   ? 466  GLY B CA  1 
ATOM   7807 C  C   . GLY B 1 474 ? -0.402  -14.777 -5.292  1   20.465 ? 466  GLY B C   1 
ATOM   7808 O  O   . GLY B 1 474 ? -0.084  -15.719 -4.588  1   21.963 ? 466  GLY B O   1 
ATOM   7809 N  N   . ASP B 1 475 ? 0.494   -13.913 -5.798  1   21.889 ? 467  ASP B N   1 
ATOM   7810 C  CA  . ASP B 1 475 ? 1.916   -13.977 -5.466  1   22.191 ? 467  ASP B CA  1 
ATOM   7811 C  C   . ASP B 1 475 ? 2.249   -12.892 -4.439  1   19.096 ? 467  ASP B C   1 
ATOM   7812 O  O   . ASP B 1 475 ? 2.137   -11.716 -4.727  1   21.587 ? 467  ASP B O   1 
ATOM   7813 C  CB  . ASP B 1 475 ? 2.824   -13.874 -6.694  1   23.491 ? 467  ASP B CB  1 
ATOM   7814 C  CG  . ASP B 1 475 ? 4.291   -13.884 -6.294  1   23.28  ? 467  ASP B CG  1 
ATOM   7815 O  OD1 . ASP B 1 475 ? 4.691   -14.887 -5.679  1   26.597 ? 467  ASP B OD1 1 
ATOM   7816 O  OD2 . ASP B 1 475 ? 4.986   -12.859 -6.555  1   28.196 ? 467  ASP B OD2 1 
ATOM   7817 N  N   . GLY B 1 476 ? 2.618   -13.327 -3.233  1   19.844 ? 468  GLY B N   1 
ATOM   7818 C  CA  . GLY B 1 476 ? 2.893   -12.344 -2.187  1   22.532 ? 468  GLY B CA  1 
ATOM   7819 C  C   . GLY B 1 476 ? 2.804   -12.995 -0.819  1   22.482 ? 468  GLY B C   1 
ATOM   7820 O  O   . GLY B 1 476 ? 3.297   -14.109 -0.621  1   23.344 ? 468  GLY B O   1 
ATOM   7821 N  N   . PHE B 1 477 ? 2.144   -12.277 0.11    1   20.222 ? 469  PHE B N   1 
ATOM   7822 C  CA  . PHE B 1 477 ? 2.133   -12.696 1.509   1   20.534 ? 469  PHE B CA  1 
ATOM   7823 C  C   . PHE B 1 477 ? 0.707   -12.838 2.007   1   18.208 ? 469  PHE B C   1 
ATOM   7824 O  O   . PHE B 1 477 ? -0.174  -12.067 1.625   1   20.357 ? 469  PHE B O   1 
ATOM   7825 C  CB  . PHE B 1 477 ? 2.9     -11.675 2.356   1   20.964 ? 469  PHE B CB  1 
ATOM   7826 C  CG  . PHE B 1 477 ? 4.33    -11.54  1.836   1   22.567 ? 469  PHE B CG  1 
ATOM   7827 C  CD1 . PHE B 1 477 ? 5.304   -12.467 2.212   1   24.034 ? 469  PHE B CD1 1 
ATOM   7828 C  CD2 . PHE B 1 477 ? 4.667   -10.48  0.977   1   22.743 ? 469  PHE B CD2 1 
ATOM   7829 C  CE1 . PHE B 1 477 ? 6.602   -12.372 1.68    1   24.233 ? 469  PHE B CE1 1 
ATOM   7830 C  CE2 . PHE B 1 477 ? 5.972   -10.384 0.456   1   23.269 ? 469  PHE B CE2 1 
ATOM   7831 C  CZ  . PHE B 1 477 ? 6.908   -11.321 0.833   1   21.174 ? 469  PHE B CZ  1 
ATOM   7832 N  N   . VAL B 1 478 ? 0.537   -13.859 2.844   1   19.433 ? 470  VAL B N   1 
ATOM   7833 C  CA  . VAL B 1 478 ? -0.728  -14.123 3.513   1   19.813 ? 470  VAL B CA  1 
ATOM   7834 C  C   . VAL B 1 478 ? -0.487  -13.959 5.009   1   17.327 ? 470  VAL B C   1 
ATOM   7835 O  O   . VAL B 1 478 ? 0.498   -14.453 5.573   1   19.429 ? 470  VAL B O   1 
ATOM   7836 C  CB  . VAL B 1 478 ? -1.306  -15.515 3.166   1   20.691 ? 470  VAL B CB  1 
ATOM   7837 C  CG1 . VAL B 1 478 ? -2.511  -15.879 4.048   1   22.714 ? 470  VAL B CG1 1 
ATOM   7838 C  CG2 . VAL B 1 478 ? -1.748  -15.527 1.699   1   20.453 ? 470  VAL B CG2 1 
ATOM   7839 N  N   . LEU B 1 479 ? -1.42   -13.226 5.65    1   16.535 ? 471  LEU B N   1 
ATOM   7840 C  CA  . LEU B 1 479 ? -1.345  -12.947 7.085   1   18.397 ? 471  LEU B CA  1 
ATOM   7841 C  C   . LEU B 1 479 ? -2.63   -13.444 7.729   1   16.489 ? 471  LEU B C   1 
ATOM   7842 O  O   . LEU B 1 479 ? -3.695  -13.408 7.096   1   16.326 ? 471  LEU B O   1 
ATOM   7843 C  CB  . LEU B 1 479 ? -1.247  -11.443 7.336   1   17.859 ? 471  LEU B CB  1 
ATOM   7844 C  CG  . LEU B 1 479 ? 0.046   -10.759 6.857   1   20.919 ? 471  LEU B CG  1 
ATOM   7845 C  CD1 . LEU B 1 479 ? -0.058  -10.38  5.386   1   24.96  ? 471  LEU B CD1 1 
ATOM   7846 C  CD2 . LEU B 1 479 ? 0.2     -9.456  7.649   1   22.548 ? 471  LEU B CD2 1 
ATOM   7847 N  N   . ALA B 1 480 ? -2.523  -13.887 8.974   1   15.931 ? 472  ALA B N   1 
ATOM   7848 C  CA  . ALA B 1 480 ? -3.699  -14.356 9.71    1   16.645 ? 472  ALA B CA  1 
ATOM   7849 C  C   . ALA B 1 480 ? -3.378  -14.405 11.191  1   16.516 ? 472  ALA B C   1 
ATOM   7850 O  O   . ALA B 1 480 ? -2.224  -14.585 11.57   1   18.162 ? 472  ALA B O   1 
ATOM   7851 C  CB  . ALA B 1 480 ? -4.204  -15.737 9.214   1   17.791 ? 472  ALA B CB  1 
ATOM   7852 N  N   . ILE B 1 481 ? -4.438  -14.22  12.005  1   17.003 ? 473  ILE B N   1 
ATOM   7853 C  CA  . ILE B 1 481 ? -4.293  -14.333 13.466  1   15.764 ? 473  ILE B CA  1 
ATOM   7854 C  C   . ILE B 1 481 ? -4.34   -15.802 13.881  1   16.476 ? 473  ILE B C   1 
ATOM   7855 O  O   . ILE B 1 481 ? -5.262  -16.551 13.509  1   16.874 ? 473  ILE B O   1 
ATOM   7856 C  CB  . ILE B 1 481 ? -5.376  -13.511 14.198  1   15.171 ? 473  ILE B CB  1 
ATOM   7857 C  CG1 . ILE B 1 481 ? -5.444  -12.053 13.695  1   18.68  ? 473  ILE B CG1 1 
ATOM   7858 C  CG2 . ILE B 1 481 ? -5.139  -13.599 15.724  1   17.182 ? 473  ILE B CG2 1 
ATOM   7859 C  CD1 . ILE B 1 481 ? -4.173  -11.225 13.793  1   18.212 ? 473  ILE B CD1 1 
ATOM   7860 N  N   . VAL B 1 482 ? -3.322  -16.199 14.674  1   16.895 ? 474  VAL B N   1 
ATOM   7861 C  CA  . VAL B 1 482 ? -3.256  -17.54  15.248  1   17.873 ? 474  VAL B CA  1 
ATOM   7862 C  C   . VAL B 1 482 ? -3.492  -17.459 16.747  1   18.694 ? 474  VAL B C   1 
ATOM   7863 O  O   . VAL B 1 482 ? -2.864  -16.642 17.438  1   18.778 ? 474  VAL B O   1 
ATOM   7864 C  CB  . VAL B 1 482 ? -1.877  -18.159 14.953  1   19.016 ? 474  VAL B CB  1 
ATOM   7865 C  CG1 . VAL B 1 482 ? -1.649  -19.469 15.71   1   19.046 ? 474  VAL B CG1 1 
ATOM   7866 C  CG2 . VAL B 1 482 ? -1.698  -18.417 13.469  1   20.493 ? 474  VAL B CG2 1 
ATOM   7867 N  N   . ASP B 1 483 ? -4.419  -18.28  17.221  1   17.724 ? 475  ASP B N   1 
ATOM   7868 C  CA  . ASP B 1 483 ? -4.637  -18.469 18.655  1   19.876 ? 475  ASP B CA  1 
ATOM   7869 C  C   . ASP B 1 483 ? -3.723  -19.567 19.169  1   19.427 ? 475  ASP B C   1 
ATOM   7870 O  O   . ASP B 1 483 ? -3.855  -20.73  18.754  1   21.231 ? 475  ASP B O   1 
ATOM   7871 C  CB  . ASP B 1 483 ? -6.073  -18.89  18.926  1   19.425 ? 475  ASP B CB  1 
ATOM   7872 C  CG  . ASP B 1 483 ? -7.104  -17.928 18.374  1   25.212 ? 475  ASP B CG  1 
ATOM   7873 O  OD1 . ASP B 1 483 ? -7.441  -18.107 17.168  1   25.032 ? 475  ASP B OD1 1 
ATOM   7874 O  OD2 . ASP B 1 483 ? -7.506  -16.979 19.125  1   25.072 ? 475  ASP B OD2 1 
ATOM   7875 N  N   . ARG B 1 484 ? -2.76   -19.203 20.038  1   19.786 ? 476  ARG B N   1 
ATOM   7876 C  CA  . ARG B 1 484 ? -1.907  -20.178 20.702  1   22.072 ? 476  ARG B CA  1 
ATOM   7877 C  C   . ARG B 1 484 ? -2.637  -20.597 21.971  1   24.215 ? 476  ARG B C   1 
ATOM   7878 O  O   . ARG B 1 484 ? -2.478  -19.961 23.015  1   24.543 ? 476  ARG B O   1 
ATOM   7879 C  CB  . ARG B 1 484 ? -0.519  -19.565 20.975  1   22.044 ? 476  ARG B CB  1 
ATOM   7880 C  CG  . ARG B 1 484 ? 0.275   -19.12  19.744  1   20.771 ? 476  ARG B CG  1 
ATOM   7881 C  CD  . ARG B 1 484 ? 0.618   -20.224 18.711  1   19.446 ? 476  ARG B CD  1 
ATOM   7882 N  NE  . ARG B 1 484 ? 1.463   -21.228 19.388  1   20.658 ? 476  ARG B NE  1 
ATOM   7883 C  CZ  . ARG B 1 484 ? 2.797   -21.216 19.354  1   22.543 ? 476  ARG B CZ  1 
ATOM   7884 N  NH1 . ARG B 1 484 ? 3.479   -20.267 18.715  1   24.353 ? 476  ARG B NH1 1 
ATOM   7885 N  NH2 . ARG B 1 484 ? 3.46    -22.129 20.055  1   23.661 ? 476  ARG B NH2 1 
ATOM   7886 N  N   . LEU B 1 485 ? -3.519  -21.604 21.842  1   24.771 ? 477  LEU B N   1 
ATOM   7887 C  CA  . LEU B 1 485 ? -4.496  -21.911 22.879  1   24.963 ? 477  LEU B CA  1 
ATOM   7888 C  C   . LEU B 1 485 ? -3.862  -22.313 24.206  1   26.17  ? 477  LEU B C   1 
ATOM   7889 O  O   . LEU B 1 485 ? -4.439  -22.022 25.246  1   31.74  ? 477  LEU B O   1 
ATOM   7890 C  CB  . LEU B 1 485 ? -5.518  -22.948 22.421  1   24.024 ? 477  LEU B CB  1 
ATOM   7891 C  CG  . LEU B 1 485 ? -6.332  -22.529 21.192  1   23.878 ? 477  LEU B CG  1 
ATOM   7892 C  CD1 . LEU B 1 485 ? -7.027  -23.773 20.598  1   25.494 ? 477  LEU B CD1 1 
ATOM   7893 C  CD2 . LEU B 1 485 ? -7.376  -21.464 21.528  1   25.249 ? 477  LEU B CD2 1 
ATOM   7894 N  N   . ASP B 1 486 ? -2.709  -22.983 24.17   1   27.133 ? 478  ASP B N   1 
ATOM   7895 C  CA  . ASP B 1 486 ? -2.074  -23.411 25.417  1   29.166 ? 478  ASP B CA  1 
ATOM   7896 C  C   . ASP B 1 486 ? -1.271  -22.272 26.059  1   29.094 ? 478  ASP B C   1 
ATOM   7897 O  O   . ASP B 1 486 ? -0.823  -22.416 27.196  1   29.779 ? 478  ASP B O   1 
ATOM   7898 C  CB  . ASP B 1 486 ? -1.238  -24.672 25.222  1   30.967 ? 478  ASP B CB  1 
ATOM   7899 C  CG  . ASP B 1 486 ? -0.255  -24.632 24.058  1   42.245 ? 478  ASP B CG  1 
ATOM   7900 O  OD1 . ASP B 1 486 ? -0.265  -23.629 23.288  1   38.345 ? 478  ASP B OD1 1 
ATOM   7901 O  OD2 . ASP B 1 486 ? 0.48    -25.625 23.89   1   45.779 ? 478  ASP B OD2 1 
ATOM   7902 N  N   . LEU B 1 487 ? -1.097  -21.141 25.353  1   28.479 ? 479  LEU B N   1 
ATOM   7903 C  CA  . LEU B 1 487 ? -0.24   -20.056 25.811  1   26.158 ? 479  LEU B CA  1 
ATOM   7904 C  C   . LEU B 1 487 ? -1.019  -18.804 26.212  1   29.272 ? 479  LEU B C   1 
ATOM   7905 O  O   . LEU B 1 487 ? -0.381  -17.845 26.669  1   26.088 ? 479  LEU B O   1 
ATOM   7906 C  CB  . LEU B 1 487 ? 0.862   -19.779 24.783  1   28.688 ? 479  LEU B CB  1 
ATOM   7907 C  CG  . LEU B 1 487 ? 1.789   -20.954 24.431  1   31.705 ? 479  LEU B CG  1 
ATOM   7908 C  CD1 . LEU B 1 487 ? 2.748   -20.636 23.281  1   31.668 ? 479  LEU B CD1 1 
ATOM   7909 C  CD2 . LEU B 1 487 ? 2.541   -21.521 25.644  1   32.993 ? 479  LEU B CD2 1 
ATOM   7910 N  N   . ASN B 1 488 ? -2.368  -18.785 26.056  1   23.442 ? 480  ASN B N   1 
ATOM   7911 C  CA  . ASN B 1 488 ? -3.149  -17.58  26.318  1   24.244 ? 480  ASN B CA  1 
ATOM   7912 C  C   . ASN B 1 488 ? -2.495  -16.402 25.582  1   21.072 ? 480  ASN B C   1 
ATOM   7913 O  O   . ASN B 1 488 ? -2.375  -15.308 26.127  1   24.041 ? 480  ASN B O   1 
ATOM   7914 C  CB  . ASN B 1 488 ? -3.377  -17.306 27.816  1   26.838 ? 480  ASN B CB  1 
ATOM   7915 C  CG  . ASN B 1 488 ? -4.381  -16.199 28.155  1   25.594 ? 480  ASN B CG  1 
ATOM   7916 O  OD1 . ASN B 1 488 ? -5.413  -16.074 27.501  1   25.334 ? 480  ASN B OD1 1 
ATOM   7917 N  ND2 . ASN B 1 488 ? -4.163  -15.413 29.21   1   23.336 ? 480  ASN B ND2 1 
ATOM   7918 N  N   . ARG B 1 489 ? -2.148  -16.611 24.288  1   21.077 ? 481  ARG B N   1 
ATOM   7919 C  CA  . ARG B 1 489 ? -1.698  -15.495 23.463  1   19.169 ? 481  ARG B CA  1 
ATOM   7920 C  C   . ARG B 1 489 ? -2.154  -15.669 22.015  1   16.427 ? 481  ARG B C   1 
ATOM   7921 O  O   . ARG B 1 489 ? -2.496  -16.758 21.578  1   18.969 ? 481  ARG B O   1 
ATOM   7922 C  CB  . ARG B 1 489 ? -0.182  -15.265 23.564  1   22.679 ? 481  ARG B CB  1 
ATOM   7923 C  CG  . ARG B 1 489 ? 0.662   -16.305 22.83   1   25.59  ? 481  ARG B CG  1 
ATOM   7924 C  CD  . ARG B 1 489 ? 2.093   -15.701 22.758  1   26.396 ? 481  ARG B CD  1 
ATOM   7925 N  NE  . ARG B 1 489 ? 2.99    -16.516 21.932  1   32.912 ? 481  ARG B NE  1 
ATOM   7926 C  CZ  . ARG B 1 489 ? 3.995   -17.242 22.402  1   32.72  ? 481  ARG B CZ  1 
ATOM   7927 N  NH1 . ARG B 1 489 ? 4.253   -17.282 23.708  1   35.251 ? 481  ARG B NH1 1 
ATOM   7928 N  NH2 . ARG B 1 489 ? 4.739   -17.945 21.549  1   33.647 ? 481  ARG B NH2 1 
ATOM   7929 N  N   . SER B 1 490 ? -2.151  -14.571 21.281  1   16.347 ? 482  SER B N   1 
ATOM   7930 C  CA  . SER B 1 490 ? -2.456  -14.477 19.853  1   14.883 ? 482  SER B CA  1 
ATOM   7931 C  C   . SER B 1 490 ? -1.227  -13.972 19.125  1   17.96  ? 482  SER B C   1 
ATOM   7932 O  O   . SER B 1 490 ? -0.409  -13.25  19.703  1   16.941 ? 482  SER B O   1 
ATOM   7933 C  CB  . SER B 1 490 ? -3.599  -13.531 19.575  1   16.065 ? 482  SER B CB  1 
ATOM   7934 O  OG  . SER B 1 490 ? -4.8    -13.961 20.252  1   18.004 ? 482  SER B OG  1 
ATOM   7935 N  N   . GLU B 1 491 ? -1.068  -14.436 17.875  1   16.666 ? 483  GLU B N   1 
ATOM   7936 C  CA  . GLU B 1 491 ? 0.062   -14.036 17.051  1   18.175 ? 483  GLU B CA  1 
ATOM   7937 C  C   . GLU B 1 491 ? -0.415  -13.793 15.626  1   19.247 ? 483  GLU B C   1 
ATOM   7938 O  O   . GLU B 1 491 ? -1.501  -14.217 15.248  1   18.874 ? 483  GLU B O   1 
ATOM   7939 C  CB  . GLU B 1 491 ? 1.107   -15.158 16.997  1   19.733 ? 483  GLU B CB  1 
ATOM   7940 C  CG  . GLU B 1 491 ? 1.555   -15.698 18.35   1   25.108 ? 483  GLU B CG  1 
ATOM   7941 C  CD  . GLU B 1 491 ? 2.645   -16.742 18.201  1   23.835 ? 483  GLU B CD  1 
ATOM   7942 O  OE1 . GLU B 1 491 ? 2.575   -17.587 17.301  1   25.502 ? 483  GLU B OE1 1 
ATOM   7943 O  OE2 . GLU B 1 491 ? 3.44    -16.742 19.148  1   27.635 ? 483  GLU B OE2 1 
ATOM   7944 N  N   . VAL B 1 492 ? 0.334   -13.011 14.863  1   17.502 ? 484  VAL B N   1 
ATOM   7945 C  CA  . VAL B 1 492 ? 0.042   -12.87  13.441  1   16.503 ? 484  VAL B CA  1 
ATOM   7946 C  C   . VAL B 1 492 ? 1.074   -13.713 12.705  1   18.307 ? 484  VAL B C   1 
ATOM   7947 O  O   . VAL B 1 492 ? 2.261   -13.467 12.86   1   19.472 ? 484  VAL B O   1 
ATOM   7948 C  CB  . VAL B 1 492 ? 0.135   -11.41  12.94   1   18.633 ? 484  VAL B CB  1 
ATOM   7949 C  CG1 . VAL B 1 492 ? -0.373  -11.262 11.502  1   19.778 ? 484  VAL B CG1 1 
ATOM   7950 C  CG2 . VAL B 1 492 ? -0.602  -10.438 13.875  1   18.86  ? 484  VAL B CG2 1 
ATOM   7951 N  N   . VAL B 1 493 ? 0.63    -14.642 11.865  1   17.592 ? 485  VAL B N   1 
ATOM   7952 C  CA  . VAL B 1 493 ? 1.607   -15.386 11.051  1   18.258 ? 485  VAL B CA  1 
ATOM   7953 C  C   . VAL B 1 493 ? 1.694   -14.726 9.682   1   18.941 ? 485  VAL B C   1 
ATOM   7954 O  O   . VAL B 1 493 ? 0.721   -14.152 9.204   1   18.014 ? 485  VAL B O   1 
ATOM   7955 C  CB  . VAL B 1 493 ? 1.349   -16.891 10.93   1   21.563 ? 485  VAL B CB  1 
ATOM   7956 C  CG1 . VAL B 1 493 ? 1.541   -17.537 12.283  1   25.873 ? 485  VAL B CG1 1 
ATOM   7957 C  CG2 . VAL B 1 493 ? 0.015   -17.207 10.224  1   20.171 ? 485  VAL B CG2 1 
ATOM   7958 N  N   . VAL B 1 494 ? 2.886   -14.816 9.086   1   18.146 ? 486  VAL B N   1 
ATOM   7959 C  CA  . VAL B 1 494 ? 3.115   -14.248 7.768   1   19.844 ? 486  VAL B CA  1 
ATOM   7960 C  C   . VAL B 1 494 ? 3.668   -15.407 6.933   1   18.672 ? 486  VAL B C   1 
ATOM   7961 O  O   . VAL B 1 494 ? 4.674   -16.006 7.309   1   19.6   ? 486  VAL B O   1 
ATOM   7962 C  CB  . VAL B 1 494 ? 4.13    -13.084 7.799   1   20.701 ? 486  VAL B CB  1 
ATOM   7963 C  CG1 . VAL B 1 494 ? 4.365   -12.479 6.427   1   22.598 ? 486  VAL B CG1 1 
ATOM   7964 C  CG2 . VAL B 1 494 ? 3.707   -11.988 8.762   1   21.766 ? 486  VAL B CG2 1 
ATOM   7965 N  N   . ILE B 1 495 ? 2.981   -15.677 5.815   1   20.86  ? 487  ILE B N   1 
ATOM   7966 C  CA  . ILE B 1 495 ? 3.336   -16.78  4.903   1   22.091 ? 487  ILE B CA  1 
ATOM   7967 C  C   . ILE B 1 495 ? 3.667   -16.163 3.547   1   20.207 ? 487  ILE B C   1 
ATOM   7968 O  O   . ILE B 1 495 ? 2.915   -15.342 3.035   1   20.653 ? 487  ILE B O   1 
ATOM   7969 C  CB  . ILE B 1 495 ? 2.148   -17.752 4.806   1   20.895 ? 487  ILE B CB  1 
ATOM   7970 C  CG1 . ILE B 1 495 ? 1.87    -18.447 6.143   1   19.608 ? 487  ILE B CG1 1 
ATOM   7971 C  CG2 . ILE B 1 495 ? 2.406   -18.834 3.732   1   18.885 ? 487  ILE B CG2 1 
ATOM   7972 C  CD1 . ILE B 1 495 ? 0.418   -18.861 6.304   1   23.334 ? 487  ILE B CD1 1 
ATOM   7973 N  N   . ASP B 1 496 ? 4.766   -16.636 2.918   1   21.217 ? 488  ASP B N   1 
ATOM   7974 C  CA  . ASP B 1 496 ? 5.055   -16.332 1.518   1   22.01  ? 488  ASP B CA  1 
ATOM   7975 C  C   . ASP B 1 496 ? 4.389   -17.408 0.65    1   21.257 ? 488  ASP B C   1 
ATOM   7976 O  O   . ASP B 1 496 ? 4.58    -18.609 0.904   1   21.95  ? 488  ASP B O   1 
ATOM   7977 C  CB  . ASP B 1 496 ? 6.566   -16.293 1.315   1   22.092 ? 488  ASP B CB  1 
ATOM   7978 C  CG  . ASP B 1 496 ? 7.022   -15.806 -0.052  1   25.076 ? 488  ASP B CG  1 
ATOM   7979 O  OD1 . ASP B 1 496 ? 6.377   -16.194 -1.032  1   23.843 ? 488  ASP B OD1 1 
ATOM   7980 O  OD2 . ASP B 1 496 ? 7.976   -14.996 -0.117  1   26.187 ? 488  ASP B OD2 1 
ATOM   7981 N  N   . THR B 1 497 ? 3.537   -16.985 -0.302  1   20.148 ? 489  THR B N   1 
ATOM   7982 C  CA  . THR B 1 497 ? 2.833   -17.898 -1.193  1   22.059 ? 489  THR B CA  1 
ATOM   7983 C  C   . THR B 1 497 ? 3.78    -18.812 -1.987  1   25.34  ? 489  THR B C   1 
ATOM   7984 O  O   . THR B 1 497 ? 3.318   -19.814 -2.509  1   25.591 ? 489  THR B O   1 
ATOM   7985 C  CB  . THR B 1 497 ? 1.88    -17.156 -2.131  1   22.534 ? 489  THR B CB  1 
ATOM   7986 O  OG1 . THR B 1 497 ? 2.648   -16.251 -2.918  1   24.683 ? 489  THR B OG1 1 
ATOM   7987 C  CG2 . THR B 1 497 ? 0.819   -16.4   -1.359  1   23.163 ? 489  THR B CG2 1 
ATOM   7988 N  N   . ARG B 1 498 ? 5.076   -18.485 -2.048  1   23.327 ? 490  ARG B N   1 
ATOM   7989 C  CA  . ARG B 1 498 ? 6.024   -19.369 -2.723  1   23.59  ? 490  ARG B CA  1 
ATOM   7990 C  C   . ARG B 1 498 ? 6.215   -20.671 -1.958  1   29.302 ? 490  ARG B C   1 
ATOM   7991 O  O   . ARG B 1 498 ? 6.638   -21.68  -2.536  1   26.885 ? 490  ARG B O   1 
ATOM   7992 C  CB  . ARG B 1 498 ? 7.403   -18.738 -2.914  1   27.621 ? 490  ARG B CB  1 
ATOM   7993 C  CG  . ARG B 1 498 ? 7.393   -17.632 -3.949  1   32.821 ? 490  ARG B CG  1 
ATOM   7994 C  CD  . ARG B 1 498 ? 8.688   -16.944 -3.626  1   38.369 ? 490  ARG B CD  1 
ATOM   7995 N  NE  . ARG B 1 498 ? 8.922   -15.803 -4.51   1   45.278 ? 490  ARG B NE  1 
ATOM   7996 C  CZ  . ARG B 1 498 ? 9.968   -14.985 -4.42   1   53.946 ? 490  ARG B CZ  1 
ATOM   7997 N  NH1 . ARG B 1 498 ? 11.003  -15.302 -3.645  1   46.702 ? 490  ARG B NH1 1 
ATOM   7998 N  NH2 . ARG B 1 498 ? 9.972   -13.869 -5.134  1   54.733 ? 490  ARG B NH2 1 
ATOM   7999 N  N   . ASP B 1 499 ? 5.942   -20.656 -0.65   1   25.04  ? 491  ASP B N   1 
ATOM   8000 C  CA  . ASP B 1 499 ? 5.81    -21.897 0.094   1   29.025 ? 491  ASP B CA  1 
ATOM   8001 C  C   . ASP B 1 499 ? 4.724   -21.73  1.145   1   25.658 ? 491  ASP B C   1 
ATOM   8002 O  O   . ASP B 1 499 ? 5.013   -21.382 2.289   1   25.272 ? 491  ASP B O   1 
ATOM   8003 C  CB  . ASP B 1 499 ? 7.1     -22.379 0.736   1   28.113 ? 491  ASP B CB  1 
ATOM   8004 C  CG  . ASP B 1 499 ? 7.015   -23.701 1.5     1   30.055 ? 491  ASP B CG  1 
ATOM   8005 O  OD1 . ASP B 1 499 ? 5.914   -24.38  1.519   1   31.853 ? 491  ASP B OD1 1 
ATOM   8006 O  OD2 . ASP B 1 499 ? 8.028   -24.023 2.148   1   36.145 ? 491  ASP B OD2 1 
ATOM   8007 N  N   . PHE B 1 500 ? 3.508   -22.093 0.748   1   25.877 ? 492  PHE B N   1 
ATOM   8008 C  CA  . PHE B 1 500 ? 2.345   -21.827 1.573   1   22.669 ? 492  PHE B CA  1 
ATOM   8009 C  C   . PHE B 1 500 ? 2.347   -22.654 2.856   1   27.061 ? 492  PHE B C   1 
ATOM   8010 O  O   . PHE B 1 500 ? 1.617   -22.306 3.77    1   23.548 ? 492  PHE B O   1 
ATOM   8011 C  CB  . PHE B 1 500 ? 1.085   -22.095 0.748   1   22.725 ? 492  PHE B CB  1 
ATOM   8012 C  CG  . PHE B 1 500 ? -0.15   -21.447 1.39    1   22.605 ? 492  PHE B CG  1 
ATOM   8013 C  CD1 . PHE B 1 500 ? -0.294  -20.048 1.353   1   22.587 ? 492  PHE B CD1 1 
ATOM   8014 C  CD2 . PHE B 1 500 ? -1.151  -22.235 1.971   1   22.488 ? 492  PHE B CD2 1 
ATOM   8015 C  CE1 . PHE B 1 500 ? -1.42   -19.44  1.9     1   20.62  ? 492  PHE B CE1 1 
ATOM   8016 C  CE2 . PHE B 1 500 ? -2.266  -21.619 2.543   1   22.455 ? 492  PHE B CE2 1 
ATOM   8017 C  CZ  . PHE B 1 500 ? -2.412  -20.219 2.473   1   22.802 ? 492  PHE B CZ  1 
ATOM   8018 N  N   . THR B 1 501 ? 3.155   -23.726 2.938   1   24.357 ? 493  THR B N   1 
ATOM   8019 C  CA  . THR B 1 501 ? 3.171   -24.598 4.099   1   23.538 ? 493  THR B CA  1 
ATOM   8020 C  C   . THR B 1 501 ? 3.975   -24.008 5.267   1   23.348 ? 493  THR B C   1 
ATOM   8021 O  O   . THR B 1 501 ? 3.917   -24.602 6.339   1   25.426 ? 493  THR B O   1 
ATOM   8022 C  CB  . THR B 1 501 ? 3.681   -26.009 3.748   1   28.288 ? 493  THR B CB  1 
ATOM   8023 O  OG1 . THR B 1 501 ? 5.101   -25.886 3.608   1   26.432 ? 493  THR B OG1 1 
ATOM   8024 C  CG2 . THR B 1 501 ? 3.001   -26.604 2.523   1   27.923 ? 493  THR B CG2 1 
ATOM   8025 N  N   . LYS B 1 502 ? 4.7     -22.904 5.059   1   23.689 ? 494  LYS B N   1 
ATOM   8026 C  CA  . LYS B 1 502 ? 5.68    -22.441 6.032   1   27.659 ? 494  LYS B CA  1 
ATOM   8027 C  C   . LYS B 1 502 ? 5.48    -20.952 6.323   1   23.159 ? 494  LYS B C   1 
ATOM   8028 O  O   . LYS B 1 502 ? 5.412   -20.122 5.41    1   24.959 ? 494  LYS B O   1 
ATOM   8029 C  CB  . LYS B 1 502 ? 7.088   -22.724 5.49    1   33.656 ? 494  LYS B CB  1 
ATOM   8030 C  CG  . LYS B 1 502 ? 8.209   -22.5   6.491   1   40.33  ? 494  LYS B CG  1 
ATOM   8031 C  CD  . LYS B 1 502 ? 9.546   -23.079 6.046   1   50.869 ? 494  LYS B CD  1 
ATOM   8032 C  CE  . LYS B 1 502 ? 10.597  -22.615 6.99    1   51.251 ? 494  LYS B CE  1 
ATOM   8033 N  NZ  . LYS B 1 502 ? 11.912  -23.03  6.494   1   66.511 ? 494  LYS B NZ  1 
ATOM   8034 N  N   . ALA B 1 503 ? 5.46    -20.623 7.623   1   23.605 ? 495  ALA B N   1 
ATOM   8035 C  CA  . ALA B 1 503 ? 5.516   -19.241 8.044   1   24.299 ? 495  ALA B CA  1 
ATOM   8036 C  C   . ALA B 1 503 ? 6.936   -18.695 7.9     1   21.362 ? 495  ALA B C   1 
ATOM   8037 O  O   . ALA B 1 503 ? 7.885   -19.375 8.288   1   25.818 ? 495  ALA B O   1 
ATOM   8038 C  CB  . ALA B 1 503 ? 5.058   -19.172 9.485   1   24.853 ? 495  ALA B CB  1 
ATOM   8039 N  N   . VAL B 1 504 ? 7.06    -17.469 7.376   1   20.616 ? 496  VAL B N   1 
ATOM   8040 C  CA  . VAL B 1 504 ? 8.327   -16.76  7.334   1   23.382 ? 496  VAL B CA  1 
ATOM   8041 C  C   . VAL B 1 504 ? 8.536   -15.925 8.595   1   22.799 ? 496  VAL B C   1 
ATOM   8042 O  O   . VAL B 1 504 ? 9.679   -15.649 8.956   1   24.374 ? 496  VAL B O   1 
ATOM   8043 C  CB  . VAL B 1 504 ? 8.595   -15.936 6.068   1   24.765 ? 496  VAL B CB  1 
ATOM   8044 C  CG1 . VAL B 1 504 ? 8.596   -16.808 4.821   1   25.888 ? 496  VAL B CG1 1 
ATOM   8045 C  CG2 . VAL B 1 504 ? 7.598   -14.8   5.868   1   25.405 ? 496  VAL B CG2 1 
ATOM   8046 N  N   . ALA B 1 505 ? 7.436   -15.494 9.246   1   20.622 ? 497  ALA B N   1 
ATOM   8047 C  CA  . ALA B 1 505 ? 7.558   -14.636 10.418  1   20.632 ? 497  ALA B CA  1 
ATOM   8048 C  C   . ALA B 1 505 ? 6.291   -14.816 11.258  1   22.672 ? 497  ALA B C   1 
ATOM   8049 O  O   . ALA B 1 505 ? 5.259   -15.27  10.764  1   18.783 ? 497  ALA B O   1 
ATOM   8050 C  CB  . ALA B 1 505 ? 7.775   -13.167 10.047  1   21.292 ? 497  ALA B CB  1 
ATOM   8051 N  N   . ALA B 1 506 ? 6.409   -14.49  12.547  1   19.746 ? 498  ALA B N   1 
ATOM   8052 C  CA  . ALA B 1 506 ? 5.275   -14.402 13.462  1   19.515 ? 498  ALA B CA  1 
ATOM   8053 C  C   . ALA B 1 506 ? 5.422   -13.109 14.24   1   22.369 ? 498  ALA B C   1 
ATOM   8054 O  O   . ALA B 1 506 ? 6.537   -12.772 14.647  1   24.235 ? 498  ALA B O   1 
ATOM   8055 C  CB  . ALA B 1 506 ? 5.163   -15.585 14.394  1   20.832 ? 498  ALA B CB  1 
ATOM   8056 N  N   . VAL B 1 507 ? 4.304   -12.388 14.399  1   18.38  ? 499  VAL B N   1 
ATOM   8057 C  CA  . VAL B 1 507 ? 4.224   -11.218 15.253  1   16.667 ? 499  VAL B CA  1 
ATOM   8058 C  C   . VAL B 1 507 ? 3.623   -11.723 16.555  1   17.695 ? 499  VAL B C   1 
ATOM   8059 O  O   . VAL B 1 507 ? 2.523   -12.245 16.576  1   20.813 ? 499  VAL B O   1 
ATOM   8060 C  CB  . VAL B 1 507 ? 3.323   -10.175 14.582  1   18.179 ? 499  VAL B CB  1 
ATOM   8061 C  CG1 . VAL B 1 507 ? 3.216   -8.935  15.479  1   18.562 ? 499  VAL B CG1 1 
ATOM   8062 C  CG2 . VAL B 1 507 ? 3.837   -9.766  13.206  1   18.562 ? 499  VAL B CG2 1 
ATOM   8063 N  N   . GLN B 1 508 ? 4.404   -11.664 17.635  1   16.432 ? 500  GLN B N   1 
ATOM   8064 C  CA  . GLN B 1 508 ? 4.037   -12.287 18.899  1   16.456 ? 500  GLN B CA  1 
ATOM   8065 C  C   . GLN B 1 508 ? 3.51    -11.21  19.863  1   16.553 ? 500  GLN B C   1 
ATOM   8066 O  O   . GLN B 1 508 ? 4.289   -10.496 20.498  1   18.006 ? 500  GLN B O   1 
ATOM   8067 C  CB  . GLN B 1 508 ? 5.311   -12.943 19.441  1   19.848 ? 500  GLN B CB  1 
ATOM   8068 C  CG  . GLN B 1 508 ? 5.128   -13.731 20.735  1   22.974 ? 500  GLN B CG  1 
ATOM   8069 C  CD  . GLN B 1 508 ? 6.403   -14.335 21.291  1   25.599 ? 500  GLN B CD  1 
ATOM   8070 O  OE1 . GLN B 1 508 ? 7.324   -14.709 20.536  1   24.72  ? 500  GLN B OE1 1 
ATOM   8071 N  NE2 . GLN B 1 508 ? 6.417   -14.493 22.62   1   28.172 ? 500  GLN B NE2 1 
ATOM   8072 N  N   . LEU B 1 509 ? 2.196   -11.177 20.04   1   15.897 ? 501  LEU B N   1 
ATOM   8073 C  CA  . LEU B 1 509 ? 1.617   -10.35  21.101  1   15.144 ? 501  LEU B CA  1 
ATOM   8074 C  C   . LEU B 1 509 ? 1.973   -10.965 22.437  1   16.361 ? 501  LEU B C   1 
ATOM   8075 O  O   . LEU B 1 509 ? 2.175   -12.172 22.525  1   17.016 ? 501  LEU B O   1 
ATOM   8076 C  CB  . LEU B 1 509 ? 0.098   -10.222 20.969  1   15.519 ? 501  LEU B CB  1 
ATOM   8077 C  CG  . LEU B 1 509 ? -0.366  -9.381  19.777  1   16.819 ? 501  LEU B CG  1 
ATOM   8078 C  CD1 . LEU B 1 509 ? -1.896  -9.518  19.613  1   15.734 ? 501  LEU B CD1 1 
ATOM   8079 C  CD2 . LEU B 1 509 ? -0.003  -7.866  19.863  1   16.482 ? 501  LEU B CD2 1 
ATOM   8080 N  N   . PRO B 1 510 ? 1.987   -10.166 23.534  1   15.855 ? 502  PRO B N   1 
ATOM   8081 C  CA  . PRO B 1 510 ? 2.166   -10.743 24.875  1   17.387 ? 502  PRO B CA  1 
ATOM   8082 C  C   . PRO B 1 510 ? 0.881   -11.284 25.514  1   19.557 ? 502  PRO B C   1 
ATOM   8083 O  O   . PRO B 1 510 ? 0.869   -11.71  26.675  1   22.743 ? 502  PRO B O   1 
ATOM   8084 C  CB  . PRO B 1 510 ? 2.687   -9.487  25.631  1   17.596 ? 502  PRO B CB  1 
ATOM   8085 C  CG  . PRO B 1 510 ? 1.952   -8.361  25.005  1   17.852 ? 502  PRO B CG  1 
ATOM   8086 C  CD  . PRO B 1 510 ? 1.95    -8.704  23.509  1   16.167 ? 502  PRO B CD  1 
ATOM   8087 N  N   . PHE B 1 511 ? -0.219  -11.247 24.76   1   16.889 ? 503  PHE B N   1 
ATOM   8088 C  CA  . PHE B 1 511 ? -1.535  -11.566 25.271  1   16.037 ? 503  PHE B CA  1 
ATOM   8089 C  C   . PHE B 1 511 ? -2.38   -12.059 24.104  1   16.693 ? 503  PHE B C   1 
ATOM   8090 O  O   . PHE B 1 511 ? -1.902  -12.063 22.959  1   16.691 ? 503  PHE B O   1 
ATOM   8091 C  CB  . PHE B 1 511 ? -2.148  -10.351 25.979  1   15.377 ? 503  PHE B CB  1 
ATOM   8092 C  CG  . PHE B 1 511 ? -2.221  -9.021  25.27   1   16.058 ? 503  PHE B CG  1 
ATOM   8093 C  CD1 . PHE B 1 511 ? -2.649  -8.912  23.932  1   16.316 ? 503  PHE B CD1 1 
ATOM   8094 C  CD2 . PHE B 1 511 ? -1.842  -7.843  25.931  1   16.906 ? 503  PHE B CD2 1 
ATOM   8095 C  CE1 . PHE B 1 511 ? -2.737  -7.677  23.267  1   17.669 ? 503  PHE B CE1 1 
ATOM   8096 C  CE2 . PHE B 1 511 ? -1.936  -6.624  25.274  1   17.912 ? 503  PHE B CE2 1 
ATOM   8097 C  CZ  . PHE B 1 511 ? -2.398  -6.525  23.98   1   18.643 ? 503  PHE B CZ  1 
ATOM   8098 N  N   . ALA B 1 512 ? -3.557  -12.588 24.472  1   16.792 ? 504  ALA B N   1 
ATOM   8099 C  CA  . ALA B 1 512 ? -4.565  -13.031 23.512  1   15.318 ? 504  ALA B CA  1 
ATOM   8100 C  C   . ALA B 1 512 ? -5.554  -11.915 23.267  1   16.817 ? 504  ALA B C   1 
ATOM   8101 O  O   . ALA B 1 512 ? -5.882  -11.145 24.178  1   16.943 ? 504  ALA B O   1 
ATOM   8102 C  CB  . ALA B 1 512 ? -5.294  -14.226 24.056  1   17.17  ? 504  ALA B CB  1 
ATOM   8103 N  N   . ILE B 1 513 ? -6.022  -11.848 22.019  1   16.92  ? 505  ILE B N   1 
ATOM   8104 C  CA  . ILE B 1 513 ? -7.145  -11.002 21.639  1   16.248 ? 505  ILE B CA  1 
ATOM   8105 C  C   . ILE B 1 513 ? -8.323  -11.916 21.296  1   15.907 ? 505  ILE B C   1 
ATOM   8106 O  O   . ILE B 1 513 ? -8.155  -13.136 21.119  1   15.703 ? 505  ILE B O   1 
ATOM   8107 C  CB  . ILE B 1 513 ? -6.778  -9.995  20.522  1   16.295 ? 505  ILE B CB  1 
ATOM   8108 C  CG1 . ILE B 1 513 ? -6.41   -10.708 19.167  1   16.543 ? 505  ILE B CG1 1 
ATOM   8109 C  CG2 . ILE B 1 513 ? -5.624  -9.062  21.001  1   17.184 ? 505  ILE B CG2 1 
ATOM   8110 C  CD1 . ILE B 1 513 ? -6.124  -9.73   18.025  1   17.047 ? 505  ILE B CD1 1 
ATOM   8111 N  N   . ARG B 1 514 ? -9.515  -11.317 21.217  1   15.546 ? 506  ARG B N   1 
ATOM   8112 C  CA  . ARG B 1 514 ? -10.683 -12.085 20.815  1   14.888 ? 506  ARG B CA  1 
ATOM   8113 C  C   . ARG B 1 514 ? -10.476 -12.736 19.439  1   15.043 ? 506  ARG B C   1 
ATOM   8114 O  O   . ARG B 1 514 ? -9.771  -12.196 18.588  1   16.007 ? 506  ARG B O   1 
ATOM   8115 C  CB  . ARG B 1 514 ? -11.918 -11.185 20.672  1   17.409 ? 506  ARG B CB  1 
ATOM   8116 C  CG  . ARG B 1 514 ? -12.685 -10.924 21.95   1   17.171 ? 506  ARG B CG  1 
ATOM   8117 C  CD  . ARG B 1 514 ? -13.5   -12.129 22.385  1   16.933 ? 506  ARG B CD  1 
ATOM   8118 N  NE  . ARG B 1 514 ? -14.373 -11.702 23.497  1   17.493 ? 506  ARG B NE  1 
ATOM   8119 C  CZ  . ARG B 1 514 ? -15.223 -12.544 24.052  1   17.039 ? 506  ARG B CZ  1 
ATOM   8120 N  NH1 . ARG B 1 514 ? -15.387 -13.785 23.617  1   17.762 ? 506  ARG B NH1 1 
ATOM   8121 N  NH2 . ARG B 1 514 ? -16.009 -12.145 25.008  1   19.15  ? 506  ARG B NH2 1 
ATOM   8122 N  N   . SER B 1 515 ? -11.115 -13.902 19.245  1   15.341 ? 507  SER B N   1 
ATOM   8123 C  CA  . SER B 1 515 ? -11.263 -14.465 17.905  1   16.814 ? 507  SER B CA  1 
ATOM   8124 C  C   . SER B 1 515 ? -12.296 -13.617 17.177  1   16.446 ? 507  SER B C   1 
ATOM   8125 O  O   . SER B 1 515 ? -13.375 -13.396 17.7    1   17.211 ? 507  SER B O   1 
ATOM   8126 C  CB  . SER B 1 515 ? -11.69  -15.935 17.956  1   16.068 ? 507  SER B CB  1 
ATOM   8127 O  OG  . SER B 1 515 ? -11.585 -16.484 16.626  1   17.657 ? 507  SER B OG  1 
ATOM   8128 N  N   . GLY B 1 516 ? -11.899 -13.088 16.022  1   16.451 ? 508  GLY B N   1 
ATOM   8129 C  CA  . GLY B 1 516 ? -12.703 -12.082 15.337  1   15.969 ? 508  GLY B CA  1 
ATOM   8130 C  C   . GLY B 1 516 ? -13.559 -12.639 14.203  1   17.436 ? 508  GLY B C   1 
ATOM   8131 O  O   . GLY B 1 516 ? -13.755 -13.859 14.064  1   17.913 ? 508  GLY B O   1 
ATOM   8132 N  N   . ILE B 1 517 ? -14.035 -11.666 13.419  1   16.083 ? 509  ILE B N   1 
ATOM   8133 C  CA  . ILE B 1 517 ? -14.881 -11.993 12.277  1   15.368 ? 509  ILE B CA  1 
ATOM   8134 C  C   . ILE B 1 517 ? -14.006 -11.75  11.042  1   16.808 ? 509  ILE B C   1 
ATOM   8135 O  O   . ILE B 1 517 ? -13.253 -12.669 10.68   1   16.132 ? 509  ILE B O   1 
ATOM   8136 C  CB  . ILE B 1 517 ? -16.245 -11.291 12.39   1   15.696 ? 509  ILE B CB  1 
ATOM   8137 C  CG1 . ILE B 1 517 ? -16.901 -11.689 13.738  1   16.508 ? 509  ILE B CG1 1 
ATOM   8138 C  CG2 . ILE B 1 517 ? -17.156 -11.722 11.233  1   17.212 ? 509  ILE B CG2 1 
ATOM   8139 C  CD1 . ILE B 1 517 ? -18.221 -10.969 14.065  1   17.541 ? 509  ILE B CD1 1 
ATOM   8140 N  N   . HIS B 1 518 ? -14.07  -10.554 10.441  1   15.023 ? 510  HIS B N   1 
ATOM   8141 C  CA  . HIS B 1 518 ? -13.245 -10.303 9.259   1   14.925 ? 510  HIS B CA  1 
ATOM   8142 C  C   . HIS B 1 518 ? -12.106 -9.359  9.629   1   16.862 ? 510  HIS B C   1 
ATOM   8143 O  O   . HIS B 1 518 ? -12.102 -8.689  10.684  1   16.454 ? 510  HIS B O   1 
ATOM   8144 C  CB  . HIS B 1 518 ? -14.062 -9.671  8.128   1   15.121 ? 510  HIS B CB  1 
ATOM   8145 C  CG  . HIS B 1 518 ? -15.148 -10.593 7.652   1   14.955 ? 510  HIS B CG  1 
ATOM   8146 N  ND1 . HIS B 1 518 ? -14.894 -11.712 6.873   1   14.267 ? 510  HIS B ND1 1 
ATOM   8147 C  CD2 . HIS B 1 518 ? -16.439 -10.62  7.986   1   15.599 ? 510  HIS B CD2 1 
ATOM   8148 C  CE1 . HIS B 1 518 ? -16.05  -12.345 6.686   1   15.177 ? 510  HIS B CE1 1 
ATOM   8149 N  NE2 . HIS B 1 518 ? -17.001 -11.686 7.338   1   15.544 ? 510  HIS B NE2 1 
ATOM   8150 N  N   . GLY B 1 519 ? -11.17  -9.292  8.697   1   16.065 ? 511  GLY B N   1 
ATOM   8151 C  CA  . GLY B 1 519 ? -10.12  -8.29   8.73    1   16.228 ? 511  GLY B CA  1 
ATOM   8152 C  C   . GLY B 1 519 ? -9.719  -7.992  7.302   1   17.281 ? 511  GLY B C   1 
ATOM   8153 O  O   . GLY B 1 519 ? -10.102 -8.721  6.374   1   16.143 ? 511  GLY B O   1 
ATOM   8154 N  N   . GLN B 1 520 ? -8.889  -6.952  7.159   1   15.395 ? 512  GLN B N   1 
ATOM   8155 C  CA  . GLN B 1 520 ? -8.478  -6.526  5.822   1   15.978 ? 512  GLN B CA  1 
ATOM   8156 C  C   . GLN B 1 520 ? -7.04   -6.1    5.823   1   16.098 ? 512  GLN B C   1 
ATOM   8157 O  O   . GLN B 1 520 ? -6.604  -5.391  6.75    1   16.691 ? 512  GLN B O   1 
ATOM   8158 C  CB  . GLN B 1 520 ? -9.36   -5.427  5.242   1   17.467 ? 512  GLN B CB  1 
ATOM   8159 C  CG  . GLN B 1 520 ? -10.859 -5.775  5.229   1   14.904 ? 512  GLN B CG  1 
ATOM   8160 C  CD  . GLN B 1 520 ? -11.233 -6.843  4.224   1   17.826 ? 512  GLN B CD  1 
ATOM   8161 O  OE1 . GLN B 1 520 ? -10.51  -7.113  3.257   1   18.012 ? 512  GLN B OE1 1 
ATOM   8162 N  NE2 . GLN B 1 520 ? -12.372 -7.49   4.436   1   17.551 ? 512  GLN B NE2 1 
ATOM   8163 N  N   . TRP B 1 521 ? -6.318  -6.47   4.751   1   16.807 ? 513  TRP B N   1 
ATOM   8164 C  CA  . TRP B 1 521 ? -5.039  -5.823  4.473   1   16.416 ? 513  TRP B CA  1 
ATOM   8165 C  C   . TRP B 1 521 ? -5.33   -4.517  3.768   1   17.078 ? 513  TRP B C   1 
ATOM   8166 O  O   . TRP B 1 521 ? -6.005  -4.513  2.726   1   19.56  ? 513  TRP B O   1 
ATOM   8167 C  CB  . TRP B 1 521 ? -4.138  -6.702  3.578   1   17.572 ? 513  TRP B CB  1 
ATOM   8168 C  CG  . TRP B 1 521 ? -2.827  -6.005  3.322   1   17.477 ? 513  TRP B CG  1 
ATOM   8169 C  CD1 . TRP B 1 521 ? -2.463  -5.36   2.174   1   17.48  ? 513  TRP B CD1 1 
ATOM   8170 C  CD2 . TRP B 1 521 ? -1.766  -5.777  4.279   1   17.827 ? 513  TRP B CD2 1 
ATOM   8171 N  NE1 . TRP B 1 521 ? -1.223  -4.75   2.347   1   18.478 ? 513  TRP B NE1 1 
ATOM   8172 C  CE2 . TRP B 1 521 ? -0.775  -4.996  3.626   1   16.679 ? 513  TRP B CE2 1 
ATOM   8173 C  CE3 . TRP B 1 521 ? -1.556  -6.173  5.604   1   18.442 ? 513  TRP B CE3 1 
ATOM   8174 C  CZ2 . TRP B 1 521 ? 0.404   -4.622  4.278   1   20.394 ? 513  TRP B CZ2 1 
ATOM   8175 C  CZ3 . TRP B 1 521 ? -0.393  -5.785  6.255   1   17.886 ? 513  TRP B CZ3 1 
ATOM   8176 C  CH2 . TRP B 1 521 ? 0.574   -5.03   5.582   1   19.511 ? 513  TRP B CH2 1 
ATOM   8177 N  N   A ILE B 1 522 ? -4.865  -3.418  4.36    0.5 14.841 ? 514  ILE B N   1 
ATOM   8178 N  N   B ILE B 1 522 ? -4.896  -3.415  4.375   0.5 15.071 ? 514  ILE B N   1 
ATOM   8179 C  CA  A ILE B 1 522 ? -5.072  -2.102  3.784   0.5 16.978 ? 514  ILE B CA  1 
ATOM   8180 C  CA  B ILE B 1 522 ? -5.071  -2.086  3.823   0.5 17.521 ? 514  ILE B CA  1 
ATOM   8181 C  C   A ILE B 1 522 ? -3.698  -1.531  3.466   0.5 18.422 ? 514  ILE B C   1 
ATOM   8182 C  C   B ILE B 1 522 ? -3.685  -1.564  3.467   0.5 18.551 ? 514  ILE B C   1 
ATOM   8183 O  O   A ILE B 1 522 ? -2.932  -1.206  4.38    0.5 17.663 ? 514  ILE B O   1 
ATOM   8184 O  O   B ILE B 1 522 ? -2.881  -1.294  4.359   0.5 17.09  ? 514  ILE B O   1 
ATOM   8185 C  CB  A ILE B 1 522 ? -5.9    -1.184  4.694   0.5 15.96  ? 514  ILE B CB  1 
ATOM   8186 C  CB  B ILE B 1 522 ? -5.771  -1.152  4.819   0.5 17.204 ? 514  ILE B CB  1 
ATOM   8187 C  CG1 A ILE B 1 522 ? -7.26   -1.808  4.962   0.5 16.465 ? 514  ILE B CG1 1 
ATOM   8188 C  CG1 B ILE B 1 522 ? -7.082  -1.764  5.312   0.5 18.319 ? 514  ILE B CG1 1 
ATOM   8189 C  CG2 A ILE B 1 522 ? -6.029  0.223   4.082   0.5 16.241 ? 514  ILE B CG2 1 
ATOM   8190 C  CG2 B ILE B 1 522 ? -5.973  0.235   4.189   0.5 18.05  ? 514  ILE B CG2 1 
ATOM   8191 C  CD1 A ILE B 1 522 ? -8.208  -0.886  5.702   0.5 15.289 ? 514  ILE B CD1 1 
ATOM   8192 C  CD1 B ILE B 1 522 ? -8.064  -2.092  4.214   0.5 16.252 ? 514  ILE B CD1 1 
ATOM   8193 N  N   . PRO B 1 523 ? -3.323  -1.437  2.163   1   18.724 ? 515  PRO B N   1 
ATOM   8194 C  CA  . PRO B 1 523 ? -1.992  -0.934  1.792   1   20.241 ? 515  PRO B CA  1 
ATOM   8195 C  C   . PRO B 1 523 ? -1.768  0.492   2.267   1   18.619 ? 515  PRO B C   1 
ATOM   8196 O  O   . PRO B 1 523 ? -2.701  1.311   2.369   1   19.369 ? 515  PRO B O   1 
ATOM   8197 C  CB  . PRO B 1 523 ? -1.965  -1.022  0.247   1   20.932 ? 515  PRO B CB  1 
ATOM   8198 C  CG  . PRO B 1 523 ? -3.131  -1.88   -0.103  1   23.535 ? 515  PRO B CG  1 
ATOM   8199 C  CD  . PRO B 1 523 ? -4.165  -1.831  1.009   1   18.618 ? 515  PRO B CD  1 
ATOM   8200 N  N   . GLY B 1 524 ? -0.486  0.797   2.539   1   17.782 ? 516  GLY B N   1 
ATOM   8201 C  CA  . GLY B 1 524 ? -0.138  2.154   2.935   1   17.573 ? 516  GLY B CA  1 
ATOM   8202 C  C   . GLY B 1 524 ? -0.569  3.211   1.926   1   18.618 ? 516  GLY B C   1 
ATOM   8203 O  O   . GLY B 1 524 ? -0.982  4.298   2.314   1   18.874 ? 516  GLY B O   1 
ATOM   8204 N  N   . GLU B 1 525 ? -0.493  2.849   0.623   1   21.086 ? 517  GLU B N   1 
ATOM   8205 C  CA  . GLU B 1 525 ? -0.735  3.831   -0.431  1   21.316 ? 517  GLU B CA  1 
ATOM   8206 C  C   . GLU B 1 525 ? -2.179  4.359   -0.437  1   23.294 ? 517  GLU B C   1 
ATOM   8207 O  O   . GLU B 1 525 ? -2.417  5.45    -0.961  1   23.985 ? 517  GLU B O   1 
ATOM   8208 C  CB  . GLU B 1 525 ? -0.007  3.296   -1.675  1   33.748 ? 517  GLU B CB  1 
ATOM   8209 C  CG  . GLU B 1 525 ? -0.625  3.574   -3.047  1   55.999 ? 517  GLU B CG  1 
ATOM   8210 C  CD  . GLU B 1 525 ? -1.317  2.384   -3.709  1   69.968 ? 517  GLU B CD  1 
ATOM   8211 O  OE1 . GLU B 1 525 ? -0.855  1.231   -3.517  1   70.641 ? 517  GLU B OE1 1 
ATOM   8212 O  OE2 . GLU B 1 525 ? -2.305  2.616   -4.448  1   77.88  ? 517  GLU B OE2 1 
ATOM   8213 N  N   . VAL B 1 526 ? -3.144  3.608   0.145   1   18.383 ? 518  VAL B N   1 
ATOM   8214 C  CA  . VAL B 1 526 ? -4.537  4.014   0.178   1   20.332 ? 518  VAL B CA  1 
ATOM   8215 C  C   . VAL B 1 526 ? -4.881  4.594   1.549   1   19.267 ? 518  VAL B C   1 
ATOM   8216 O  O   . VAL B 1 526 ? -6.043  4.928   1.792   1   20.502 ? 518  VAL B O   1 
ATOM   8217 C  CB  . VAL B 1 526 ? -5.542  2.905   -0.228  1   19.635 ? 518  VAL B CB  1 
ATOM   8218 C  CG1 . VAL B 1 526 ? -5.217  2.358   -1.619  1   21.076 ? 518  VAL B CG1 1 
ATOM   8219 C  CG2 . VAL B 1 526 ? -5.613  1.749   0.768   1   18.766 ? 518  VAL B CG2 1 
ATOM   8220 N  N   . THR B 1 527 ? -3.873  4.711   2.43    1   18.499 ? 519  THR B N   1 
ATOM   8221 C  CA  . THR B 1 527 ? -4.133  5.169   3.789   1   18.492 ? 519  THR B CA  1 
ATOM   8222 C  C   . THR B 1 527 ? -3.627  6.603   3.903   1   20.758 ? 519  THR B C   1 
ATOM   8223 O  O   . THR B 1 527 ? -2.402  6.816   3.806   1   19.046 ? 519  THR B O   1 
ATOM   8224 C  CB  . THR B 1 527 ? -3.398  4.262   4.789   1   18.637 ? 519  THR B CB  1 
ATOM   8225 O  OG1 . THR B 1 527 ? -3.813  2.908   4.618   1   18.696 ? 519  THR B OG1 1 
ATOM   8226 C  CG2 . THR B 1 527 ? -3.746  4.615   6.229   1   17.628 ? 519  THR B CG2 1 
ATOM   8227 N  N   . PRO B 1 528 ? -4.477  7.612   4.164   1   19.959 ? 520  PRO B N   1 
ATOM   8228 C  CA  . PRO B 1 528 ? -3.991  8.989   4.321   1   22.241 ? 520  PRO B CA  1 
ATOM   8229 C  C   . PRO B 1 528 ? -2.886  9.073   5.367   1   21.067 ? 520  PRO B C   1 
ATOM   8230 O  O   . PRO B 1 528 ? -2.992  8.495   6.464   1   21.341 ? 520  PRO B O   1 
ATOM   8231 C  CB  . PRO B 1 528 ? -5.254  9.757   4.773   1   23.152 ? 520  PRO B CB  1 
ATOM   8232 C  CG  . PRO B 1 528 ? -6.398  8.961   4.112   1   23.256 ? 520  PRO B CG  1 
ATOM   8233 C  CD  . PRO B 1 528 ? -5.953  7.508   4.249   1   19.908 ? 520  PRO B CD  1 
ATOM   8234 N  N   . ASP B 1 529 ? -1.783  9.741   5.012   1   20.052 ? 521  ASP B N   1 
ATOM   8235 C  CA  . ASP B 1 529 ? -0.664  10.066  5.9     1   20.102 ? 521  ASP B CA  1 
ATOM   8236 C  C   . ASP B 1 529 ? 0.09    8.843   6.414   1   20.1   ? 521  ASP B C   1 
ATOM   8237 O  O   . ASP B 1 529 ? 0.869   8.95    7.376   1   20.465 ? 521  ASP B O   1 
ATOM   8238 C  CB  . ASP B 1 529 ? -1.106  11.005  7.016   1   23.718 ? 521  ASP B CB  1 
ATOM   8239 C  CG  . ASP B 1 529 ? -1.861  12.237  6.545   1   28.399 ? 521  ASP B CG  1 
ATOM   8240 O  OD1 . ASP B 1 529 ? -1.216  13.03   5.846   1   37.131 ? 521  ASP B OD1 1 
ATOM   8241 O  OD2 . ASP B 1 529 ? -3.087  12.325  6.81    1   27.797 ? 521  ASP B OD2 1 
ATOM   8242 N  N   . PHE B 1 530 ? -0.047  7.695   5.735   1   20.016 ? 522  PHE B N   1 
ATOM   8243 C  CA  . PHE B 1 530 ? 0.723   6.508   6.096   1   17.805 ? 522  PHE B CA  1 
ATOM   8244 C  C   . PHE B 1 530 ? 2.233   6.762   6.19    1   19.813 ? 522  PHE B C   1 
ATOM   8245 O  O   . PHE B 1 530 ? 2.921   6.174   7.037   1   20.163 ? 522  PHE B O   1 
ATOM   8246 C  CB  . PHE B 1 530 ? 0.467   5.355   5.127   1   18.035 ? 522  PHE B CB  1 
ATOM   8247 C  CG  . PHE B 1 530 ? 1.037   4.027   5.589   1   18.137 ? 522  PHE B CG  1 
ATOM   8248 C  CD1 . PHE B 1 530 ? 0.273   3.179   6.405   1   20.065 ? 522  PHE B CD1 1 
ATOM   8249 C  CD2 . PHE B 1 530 ? 2.326   3.602   5.204   1   16.568 ? 522  PHE B CD2 1 
ATOM   8250 C  CE1 . PHE B 1 530 ? 0.795   1.953   6.8     1   20.095 ? 522  PHE B CE1 1 
ATOM   8251 C  CE2 . PHE B 1 530 ? 2.863   2.408   5.651   1   18.24  ? 522  PHE B CE2 1 
ATOM   8252 C  CZ  . PHE B 1 530 ? 2.104   1.584   6.478   1   19.789 ? 522  PHE B CZ  1 
ATOM   8253 N  N   . GLU B 1 531 ? 2.742   7.652   5.329   1   21.715 ? 523  GLU B N   1 
ATOM   8254 C  CA  . GLU B 1 531 ? 4.189   7.859   5.295   1   20.676 ? 523  GLU B CA  1 
ATOM   8255 C  C   . GLU B 1 531 ? 4.729   8.526   6.551   1   21.78  ? 523  GLU B C   1 
ATOM   8256 O  O   . GLU B 1 531 ? 5.927   8.358   6.826   1   23.93  ? 523  GLU B O   1 
ATOM   8257 C  CB  . GLU B 1 531 ? 4.592   8.625   4.026   1   23.201 ? 523  GLU B CB  1 
ATOM   8258 C  CG  . GLU B 1 531 ? 4.34    7.796   2.763   1   24.808 ? 523  GLU B CG  1 
ATOM   8259 C  CD  . GLU B 1 531 ? 4.996   6.424   2.741   1   29.287 ? 523  GLU B CD  1 
ATOM   8260 O  OE1 . GLU B 1 531 ? 6.241   6.316   2.966   1   33.601 ? 523  GLU B OE1 1 
ATOM   8261 O  OE2 . GLU B 1 531 ? 4.259   5.435   2.529   1   27.053 ? 523  GLU B OE2 1 
ATOM   8262 N  N   . THR B 1 532 ? 3.893   9.242   7.314   1   21.254 ? 524  THR B N   1 
ATOM   8263 C  CA  . THR B 1 532 ? 4.434   9.962   8.455   1   24.891 ? 524  THR B CA  1 
ATOM   8264 C  C   . THR B 1 532 ? 3.721   9.627   9.759   1   25.484 ? 524  THR B C   1 
ATOM   8265 O  O   . THR B 1 532 ? 4.255   9.991   10.821  1   26.54  ? 524  THR B O   1 
ATOM   8266 C  CB  . THR B 1 532 ? 4.432   11.486  8.236   1   23.384 ? 524  THR B CB  1 
ATOM   8267 O  OG1 . THR B 1 532 ? 3.08    11.926  8.073   1   24.636 ? 524  THR B OG1 1 
ATOM   8268 C  CG2 . THR B 1 532 ? 5.316   11.921  7.079   1   29.203 ? 524  THR B CG2 1 
ATOM   8269 N  N   . LYS B 1 533 ? 2.518   9.02    9.7     1   22.619 ? 525  LYS B N   1 
ATOM   8270 C  CA  . LYS B 1 533 ? 1.724   8.801   10.912  1   21.892 ? 525  LYS B CA  1 
ATOM   8271 C  C   . LYS B 1 533 ? 1.754   7.329   11.303  1   20.449 ? 525  LYS B C   1 
ATOM   8272 O  O   . LYS B 1 533 ? 1.39    6.467   10.517  1   23.877 ? 525  LYS B O   1 
ATOM   8273 C  CB  . LYS B 1 533 ? 0.272   9.275   10.795  1   26.953 ? 525  LYS B CB  1 
ATOM   8274 C  CG  . LYS B 1 533 ? 0.207   10.78   10.77   1   32.559 ? 525  LYS B CG  1 
ATOM   8275 C  CD  . LYS B 1 533 ? -1.197  11.375  10.848  1   33.739 ? 525  LYS B CD  1 
ATOM   8276 C  CE  . LYS B 1 533 ? -1.173  12.861  10.478  1   39.275 ? 525  LYS B CE  1 
ATOM   8277 N  NZ  . LYS B 1 533 ? 0.055   13.629  10.768  1   43.134 ? 525  LYS B NZ  1 
ATOM   8278 N  N   . GLY B 1 534 ? 2.231   7.044   12.521  1   19.98  ? 526  GLY B N   1 
ATOM   8279 C  CA  . GLY B 1 534 ? 2.244   5.671   13.019  1   18.431 ? 526  GLY B CA  1 
ATOM   8280 C  C   . GLY B 1 534 ? 1.001   5.385   13.846  1   15.309 ? 526  GLY B C   1 
ATOM   8281 O  O   . GLY B 1 534 ? 0.219   6.284   14.144  1   18.745 ? 526  GLY B O   1 
ATOM   8282 N  N   . LEU B 1 535 ? 0.862   4.116   14.261  1   15.249 ? 527  LEU B N   1 
ATOM   8283 C  CA  . LEU B 1 535 ? -0.208  3.815   15.209  1   15.846 ? 527  LEU B CA  1 
ATOM   8284 C  C   . LEU B 1 535 ? 0.112   4.387   16.591  1   17.421 ? 527  LEU B C   1 
ATOM   8285 O  O   . LEU B 1 535 ? -0.81   4.568   17.389  1   16.513 ? 527  LEU B O   1 
ATOM   8286 C  CB  . LEU B 1 535 ? -0.407  2.305   15.339  1   15.665 ? 527  LEU B CB  1 
ATOM   8287 C  CG  . LEU B 1 535 ? -0.828  1.589   14.048  1   14.575 ? 527  LEU B CG  1 
ATOM   8288 C  CD1 . LEU B 1 535 ? -0.951  0.108   14.373  1   15.682 ? 527  LEU B CD1 1 
ATOM   8289 C  CD2 . LEU B 1 535 ? -2.158  2.2     13.514  1   15.717 ? 527  LEU B CD2 1 
ATOM   8290 N  N   . VAL B 1 536 ? 1.398   4.6     16.909  1   16.106 ? 528  VAL B N   1 
ATOM   8291 C  CA  . VAL B 1 536 ? 1.823   5.125   18.2    1   16.668 ? 528  VAL B CA  1 
ATOM   8292 C  C   . VAL B 1 536 ? 2.576   6.425   17.934  1   16.647 ? 528  VAL B C   1 
ATOM   8293 O  O   . VAL B 1 536 ? 3.532   6.442   17.175  1   20.774 ? 528  VAL B O   1 
ATOM   8294 C  CB  . VAL B 1 536 ? 2.736   4.102   18.925  1   17.224 ? 528  VAL B CB  1 
ATOM   8295 C  CG1 . VAL B 1 536 ? 3.16    4.662   20.292  1   21.246 ? 528  VAL B CG1 1 
ATOM   8296 C  CG2 . VAL B 1 536 ? 2.138   2.7     19.023  1   21.708 ? 528  VAL B CG2 1 
ATOM   8297 N  N   . ASP B 1 537 ? 2.138   7.517   18.566  1   17.706 ? 529  ASP B N   1 
ATOM   8298 C  CA  . ASP B 1 537 ? 2.856   8.77    18.363  1   19.213 ? 529  ASP B CA  1 
ATOM   8299 C  C   . ASP B 1 537 ? 4.096   8.754   19.26   1   16.027 ? 529  ASP B C   1 
ATOM   8300 O  O   . ASP B 1 537 ? 4.055   8.241   20.394  1   17.932 ? 529  ASP B O   1 
ATOM   8301 C  CB  . ASP B 1 537 ? 1.995   9.948   18.789  1   19.734 ? 529  ASP B CB  1 
ATOM   8302 C  CG  . ASP B 1 537 ? 0.944   10.353  17.76   1   26.572 ? 529  ASP B CG  1 
ATOM   8303 O  OD1 . ASP B 1 537 ? 1.146   10.036  16.557  1   25.951 ? 529  ASP B OD1 1 
ATOM   8304 O  OD2 . ASP B 1 537 ? -0.057  10.947  18.191  1   30.334 ? 529  ASP B OD2 1 
ATOM   8305 N  N   . LEU B 1 538 ? 5.19    9.261   18.708  1   17.281 ? 530  LEU B N   1 
ATOM   8306 C  CA  . LEU B 1 538 ? 6.436   9.25    19.442  1   18.153 ? 530  LEU B CA  1 
ATOM   8307 C  C   . LEU B 1 538 ? 6.391   10.274  20.57   1   17.089 ? 530  LEU B C   1 
ATOM   8308 O  O   . LEU B 1 538 ? 5.686   11.296  20.525  1   19.243 ? 530  LEU B O   1 
ATOM   8309 C  CB  . LEU B 1 538 ? 7.587   9.588   18.494  1   20.177 ? 530  LEU B CB  1 
ATOM   8310 C  CG  . LEU B 1 538 ? 7.91    8.546   17.414  1   20.739 ? 530  LEU B CG  1 
ATOM   8311 C  CD1 . LEU B 1 538 ? 9.045   9.115   16.58   1   21.91  ? 530  LEU B CD1 1 
ATOM   8312 C  CD2 . LEU B 1 538 ? 8.244   7.131   17.946  1   23.189 ? 530  LEU B CD2 1 
ATOM   8313 N  N   . PRO B 1 539 ? 7.153   10.019  21.671  1   16.058 ? 531  PRO B N   1 
ATOM   8314 C  CA  . PRO B 1 539 ? 7.3     11.047  22.703  1   16.58  ? 531  PRO B CA  1 
ATOM   8315 C  C   . PRO B 1 539 ? 8.146   12.197  22.15   1   15.571 ? 531  PRO B C   1 
ATOM   8316 O  O   . PRO B 1 539 ? 8.778   12.052  21.105  1   16.795 ? 531  PRO B O   1 
ATOM   8317 C  CB  . PRO B 1 539 ? 7.993   10.289  23.865  1   18.111 ? 531  PRO B CB  1 
ATOM   8318 C  CG  . PRO B 1 539 ? 8.684   9.126   23.193  1   19.922 ? 531  PRO B CG  1 
ATOM   8319 C  CD  . PRO B 1 539 ? 7.919   8.773   21.91   1   15.787 ? 531  PRO B CD  1 
ATOM   8320 N  N   . LYS B 1 540 ? 8.17    13.315  22.867  1   15.165 ? 532  LYS B N   1 
ATOM   8321 C  CA  . LYS B 1 540 ? 8.899   14.481  22.37   1   16.302 ? 532  LYS B CA  1 
ATOM   8322 C  C   . LYS B 1 540 ? 10.413  14.241  22.359  1   16.51  ? 532  LYS B C   1 
ATOM   8323 O  O   . LYS B 1 540 ? 10.951  13.432  23.133  1   16.682 ? 532  LYS B O   1 
ATOM   8324 C  CB  . LYS B 1 540 ? 8.525   15.719  23.203  1   15.41  ? 532  LYS B CB  1 
ATOM   8325 C  CG  . LYS B 1 540 ? 9.129   15.786  24.626  1   16.697 ? 532  LYS B CG  1 
ATOM   8326 C  CD  . LYS B 1 540 ? 8.652   17.052  25.343  1   15.912 ? 532  LYS B CD  1 
ATOM   8327 C  CE  . LYS B 1 540 ? 9.41    17.214  26.66   1   17.208 ? 532  LYS B CE  1 
ATOM   8328 N  NZ  . LYS B 1 540 ? 9.1     18.56   27.188  1   18.819 ? 532  LYS B NZ  1 
ATOM   8329 N  N   . GLU B 1 541 ? 11.113  15.002  21.498  1   17.62  ? 533  GLU B N   1 
ATOM   8330 C  CA  . GLU B 1 541 ? 12.569  14.902  21.439  1   15.767 ? 533  GLU B CA  1 
ATOM   8331 C  C   . GLU B 1 541 ? 13.251  15.595  22.614  1   16.871 ? 533  GLU B C   1 
ATOM   8332 O  O   . GLU B 1 541 ? 14.206  15.011  23.145  1   17.894 ? 533  GLU B O   1 
ATOM   8333 C  CB  . GLU B 1 541 ? 12.98   15.5    20.088  1   18.969 ? 533  GLU B CB  1 
ATOM   8334 C  CG  . GLU B 1 541 ? 14.482  15.359  19.818  1   21.904 ? 533  GLU B CG  1 
ATOM   8335 C  CD  . GLU B 1 541 ? 14.913  15.809  18.436  1   29.4   ? 533  GLU B CD  1 
ATOM   8336 O  OE1 . GLU B 1 541 ? 14.096  16.367  17.675  1   31.149 ? 533  GLU B OE1 1 
ATOM   8337 O  OE2 . GLU B 1 541 ? 16.125  15.652  18.172  1   32.133 ? 533  GLU B OE2 1 
ATOM   8338 N  N   . GLU B 1 542 ? 12.819  16.8    23.005  1   17.894 ? 534  GLU B N   1 
ATOM   8339 C  CA  . GLU B 1 542 ? 13.524  17.569  24.03   1   17.165 ? 534  GLU B CA  1 
ATOM   8340 C  C   . GLU B 1 542 ? 13.595  16.732  25.319  1   16.718 ? 534  GLU B C   1 
ATOM   8341 O  O   . GLU B 1 542 ? 12.563  16.167  25.729  1   17.748 ? 534  GLU B O   1 
ATOM   8342 C  CB  . GLU B 1 542 ? 12.699  18.844  24.201  1   23.941 ? 534  GLU B CB  1 
ATOM   8343 C  CG  . GLU B 1 542 ? 13.059  19.803  25.327  1   34.717 ? 534  GLU B CG  1 
ATOM   8344 C  CD  . GLU B 1 542 ? 11.946  20.855  25.508  1   44.719 ? 534  GLU B CD  1 
ATOM   8345 O  OE1 . GLU B 1 542 ? 10.671  20.63   25.483  1   38.632 ? 534  GLU B OE1 1 
ATOM   8346 O  OE2 . GLU B 1 542 ? 12.438  21.98   25.733  1   48.867 ? 534  GLU B OE2 1 
ATOM   8347 N  N   . HIS B 1 543 ? 14.765  16.73   25.973  1   16.852 ? 535  HIS B N   1 
ATOM   8348 C  CA  . HIS B 1 543 ? 14.878  16.105  27.295  1   13.716 ? 535  HIS B CA  1 
ATOM   8349 C  C   . HIS B 1 543 ? 14.048  16.863  28.323  1   15.895 ? 535  HIS B C   1 
ATOM   8350 O  O   . HIS B 1 543 ? 13.956  18.102  28.323  1   18.292 ? 535  HIS B O   1 
ATOM   8351 C  CB  . HIS B 1 543 ? 16.338  16.069  27.752  1   15.661 ? 535  HIS B CB  1 
ATOM   8352 C  CG  . HIS B 1 543 ? 17.202  15.216  26.91   1   16.888 ? 535  HIS B CG  1 
ATOM   8353 N  ND1 . HIS B 1 543 ? 16.845  14.006  26.329  1   16.71  ? 535  HIS B ND1 1 
ATOM   8354 C  CD2 . HIS B 1 543 ? 18.479  15.468  26.462  1   18.48  ? 535  HIS B CD2 1 
ATOM   8355 C  CE1 . HIS B 1 543 ? 17.871  13.502  25.633  1   18.71  ? 535  HIS B CE1 1 
ATOM   8356 N  NE2 . HIS B 1 543 ? 18.873  14.424  25.67   1   17.668 ? 535  HIS B NE2 1 
ATOM   8357 N  N   . TRP B 1 544 ? 13.444  16.099  29.258  1   15.069 ? 536  TRP B N   1 
ATOM   8358 C  CA  . TRP B 1 544 ? 12.846  16.721  30.42   1   14.992 ? 536  TRP B CA  1 
ATOM   8359 C  C   . TRP B 1 544 ? 13.909  17.282  31.359  1   16.63  ? 536  TRP B C   1 
ATOM   8360 O  O   . TRP B 1 544 ? 13.656  18.284  32.011  1   17.831 ? 536  TRP B O   1 
ATOM   8361 C  CB  . TRP B 1 544 ? 12.046  15.683  31.229  1   14.836 ? 536  TRP B CB  1 
ATOM   8362 C  CG  . TRP B 1 544 ? 10.88   15.044  30.533  1   14.599 ? 536  TRP B CG  1 
ATOM   8363 C  CD1 . TRP B 1 544 ? 10.806  13.739  30.104  1   15.655 ? 536  TRP B CD1 1 
ATOM   8364 C  CD2 . TRP B 1 544 ? 9.599   15.662  30.207  1   15.72  ? 536  TRP B CD2 1 
ATOM   8365 N  NE1 . TRP B 1 544 ? 9.571   13.498  29.547  1   15.682 ? 536  TRP B NE1 1 
ATOM   8366 C  CE2 . TRP B 1 544 ? 8.818   14.656  29.603  1   15.258 ? 536  TRP B CE2 1 
ATOM   8367 C  CE3 . TRP B 1 544 ? 9.044   16.944  30.418  1   14.658 ? 536  TRP B CE3 1 
ATOM   8368 C  CZ2 . TRP B 1 544 ? 7.503   14.883  29.168  1   16.118 ? 536  TRP B CZ2 1 
ATOM   8369 C  CZ3 . TRP B 1 544 ? 7.735   17.172  29.978  1   16.234 ? 536  TRP B CZ3 1 
ATOM   8370 C  CH2 . TRP B 1 544 ? 6.972   16.147  29.377  1   16.468 ? 536  TRP B CH2 1 
ATOM   8371 N  N   . ALA B 1 545 ? 15.018  16.554  31.547  1   15.474 ? 537  ALA B N   1 
ATOM   8372 C  CA  . ALA B 1 545 ? 15.949  16.924  32.61   1   14.77  ? 537  ALA B CA  1 
ATOM   8373 C  C   . ALA B 1 545 ? 17.007  17.889  32.076  1   16.533 ? 537  ALA B C   1 
ATOM   8374 O  O   . ALA B 1 545 ? 17.431  17.755  30.924  1   18.029 ? 537  ALA B O   1 
ATOM   8375 C  CB  . ALA B 1 545 ? 16.664  15.665  33.096  1   14.697 ? 537  ALA B CB  1 
ATOM   8376 N  N   . PRO B 1 546 ? 17.539  18.774  32.944  1   17.635 ? 538  PRO B N   1 
ATOM   8377 C  CA  . PRO B 1 546 ? 18.685  19.605  32.531  1   18.413 ? 538  PRO B CA  1 
ATOM   8378 C  C   . PRO B 1 546 ? 19.972  18.804  32.467  1   17.527 ? 538  PRO B C   1 
ATOM   8379 O  O   . PRO B 1 546 ? 20.152  17.771  33.136  1   18.023 ? 538  PRO B O   1 
ATOM   8380 C  CB  . PRO B 1 546 ? 18.745  20.69   33.582  1   19.84  ? 538  PRO B CB  1 
ATOM   8381 C  CG  . PRO B 1 546 ? 18.211  20.013  34.833  1   19.674 ? 538  PRO B CG  1 
ATOM   8382 C  CD  . PRO B 1 546 ? 17.115  19.058  34.317  1   17.968 ? 538  PRO B CD  1 
ATOM   8383 N  N   . LEU B 1 547 ? 20.923  19.304  31.653  1   19.686 ? 539  LEU B N   1 
ATOM   8384 C  CA  . LEU B 1 547 ? 22.2    18.644  31.479  1   20.492 ? 539  LEU B CA  1 
ATOM   8385 C  C   . LEU B 1 547 ? 22.91   18.399  32.818  1   18.636 ? 539  LEU B C   1 
ATOM   8386 O  O   . LEU B 1 547 ? 23.511  17.337  32.993  1   20.74  ? 539  LEU B O   1 
ATOM   8387 C  CB  . LEU B 1 547 ? 23.071  19.533  30.573  1   26.461 ? 539  LEU B CB  1 
ATOM   8388 C  CG  . LEU B 1 547 ? 24.363  18.863  30.102  1   30.251 ? 539  LEU B CG  1 
ATOM   8389 C  CD1 . LEU B 1 547 ? 24.05   17.808  29.035  1   28.68  ? 539  LEU B CD1 1 
ATOM   8390 C  CD2 . LEU B 1 547 ? 25.326  19.944  29.542  1   36.362 ? 539  LEU B CD2 1 
ATOM   8391 N  N   . SER B 1 548 ? 22.752  19.348  33.752  1   19.059 ? 540  SER B N   1 
ATOM   8392 C  CA  . SER B 1 548 ? 23.435  19.313  35.044  1   21.806 ? 540  SER B CA  1 
ATOM   8393 C  C   . SER B 1 548 ? 23.023  18.095  35.886  1   21.144 ? 540  SER B C   1 
ATOM   8394 O  O   . SER B 1 548 ? 23.726  17.714  36.823  1   24.071 ? 540  SER B O   1 
ATOM   8395 C  CB  . SER B 1 548 ? 23.211  20.576  35.832  1   22.467 ? 540  SER B CB  1 
ATOM   8396 O  OG  . SER B 1 548 ? 21.819  20.792  36.056  1   25.095 ? 540  SER B OG  1 
ATOM   8397 N  N   . GLN B 1 549 ? 21.898  17.445  35.543  1   18.249 ? 541  GLN B N   1 
ATOM   8398 C  CA  . GLN B 1 549 ? 21.449  16.34   36.38   1   15.842 ? 541  GLN B CA  1 
ATOM   8399 C  C   . GLN B 1 549 ? 22.06   14.985  36.014  1   17.642 ? 541  GLN B C   1 
ATOM   8400 O  O   . GLN B 1 549 ? 21.793  14.009  36.703  1   17.912 ? 541  GLN B O   1 
ATOM   8401 C  CB  . GLN B 1 549 ? 19.914  16.254  36.277  1   15.543 ? 541  GLN B CB  1 
ATOM   8402 C  CG  . GLN B 1 549 ? 19.253  17.303  37.157  1   15.126 ? 541  GLN B CG  1 
ATOM   8403 C  CD  . GLN B 1 549 ? 19.128  16.845  38.612  1   15.722 ? 541  GLN B CD  1 
ATOM   8404 O  OE1 . GLN B 1 549 ? 18.548  15.783  38.937  1   15.073 ? 541  GLN B OE1 1 
ATOM   8405 N  NE2 . GLN B 1 549 ? 19.662  17.638  39.542  1   14.964 ? 541  GLN B NE2 1 
ATOM   8406 N  N   . SER B 1 550 ? 22.834  14.891  34.926  1   17.993 ? 542  SER B N   1 
ATOM   8407 C  CA  . SER B 1 550 ? 23.403  13.583  34.597  1   19.002 ? 542  SER B CA  1 
ATOM   8408 C  C   . SER B 1 550 ? 24.368  13.121  35.69   1   16.64  ? 542  SER B C   1 
ATOM   8409 O  O   . SER B 1 550 ? 25.108  13.94   36.266  1   16.972 ? 542  SER B O   1 
ATOM   8410 C  CB  . SER B 1 550 ? 24.136  13.639  33.32   1   20.252 ? 542  SER B CB  1 
ATOM   8411 O  OG  . SER B 1 550 ? 24.587  12.334  32.961  1   20.601 ? 542  SER B OG  1 
ATOM   8412 N  N   . PRO B 1 551 ? 24.362  11.794  36.011  1   17.581 ? 543  PRO B N   1 
ATOM   8413 C  CA  . PRO B 1 551 ? 25.352  11.264  36.946  1   17.028 ? 543  PRO B CA  1 
ATOM   8414 C  C   . PRO B 1 551 ? 26.764  11.353  36.381  1   16.63  ? 543  PRO B C   1 
ATOM   8415 O  O   . PRO B 1 551 ? 27.735  11.403  37.138  1   15.945 ? 543  PRO B O   1 
ATOM   8416 C  CB  . PRO B 1 551 ? 24.944  9.795   37.191  1   17.988 ? 543  PRO B CB  1 
ATOM   8417 C  CG  . PRO B 1 551 ? 24.063  9.416   35.962  1   19.182 ? 543  PRO B CG  1 
ATOM   8418 C  CD  . PRO B 1 551 ? 23.391  10.751  35.597  1   17.802 ? 543  PRO B CD  1 
ATOM   8419 N  N   . TYR B 1 552 ? 26.88   11.42   35.046  1   16.873 ? 544  TYR B N   1 
ATOM   8420 C  CA  . TYR B 1 552 ? 28.199  11.388  34.408  1   17.336 ? 544  TYR B CA  1 
ATOM   8421 C  C   . TYR B 1 552 ? 28.777  12.792  34.261  1   19.141 ? 544  TYR B C   1 
ATOM   8422 O  O   . TYR B 1 552 ? 28.111  13.717  33.81   1   20.228 ? 544  TYR B O   1 
ATOM   8423 C  CB  . TYR B 1 552 ? 27.972  10.809  33.013  1   17.953 ? 544  TYR B CB  1 
ATOM   8424 C  CG  . TYR B 1 552 ? 29.102  10.947  32.011  1   18.868 ? 544  TYR B CG  1 
ATOM   8425 C  CD1 . TYR B 1 552 ? 30.186  10.061  32.033  1   18.904 ? 544  TYR B CD1 1 
ATOM   8426 C  CD2 . TYR B 1 552 ? 29.028  11.928  31.019  1   19.156 ? 544  TYR B CD2 1 
ATOM   8427 C  CE1 . TYR B 1 552 ? 31.202  10.176  31.088  1   19.169 ? 544  TYR B CE1 1 
ATOM   8428 C  CE2 . TYR B 1 552 ? 30.028  12.039  30.048  1   20.156 ? 544  TYR B CE2 1 
ATOM   8429 C  CZ  . TYR B 1 552 ? 31.117  11.183  30.129  1   20.182 ? 544  TYR B CZ  1 
ATOM   8430 O  OH  . TYR B 1 552 ? 32.095  11.309  29.161  1   25.016 ? 544  TYR B OH  1 
ATOM   8431 N  N   . ASP B 1 553 ? 30.074  12.864  34.576  1   18.549 ? 545  ASP B N   1 
ATOM   8432 C  CA  . ASP B 1 553 ? 30.852  14.084  34.425  1   20.852 ? 545  ASP B CA  1 
ATOM   8433 C  C   . ASP B 1 553 ? 31.984  13.778  33.459  1   21.27  ? 545  ASP B C   1 
ATOM   8434 O  O   . ASP B 1 553 ? 32.804  12.937  33.769  1   21.432 ? 545  ASP B O   1 
ATOM   8435 C  CB  . ASP B 1 553 ? 31.364  14.581  35.76   1   24.334 ? 545  ASP B CB  1 
ATOM   8436 C  CG  . ASP B 1 553 ? 32.252  15.823  35.69   1   30.778 ? 545  ASP B CG  1 
ATOM   8437 O  OD1 . ASP B 1 553 ? 32.58   16.271  34.566  1   29.348 ? 545  ASP B OD1 1 
ATOM   8438 O  OD2 . ASP B 1 553 ? 32.566  16.337  36.776  1   34.878 ? 545  ASP B OD2 1 
ATOM   8439 N  N   . PRO B 1 554 ? 32.041  14.398  32.26   1   22.677 ? 546  PRO B N   1 
ATOM   8440 C  CA  . PRO B 1 554 ? 33.111  14.062  31.312  1   23.32  ? 546  PRO B CA  1 
ATOM   8441 C  C   . PRO B 1 554 ? 34.528  14.38   31.779  1   26.124 ? 546  PRO B C   1 
ATOM   8442 O  O   . PRO B 1 554 ? 35.457  13.82   31.213  1   29.185 ? 546  PRO B O   1 
ATOM   8443 C  CB  . PRO B 1 554 ? 32.743  14.869  30.05   1   27.029 ? 546  PRO B CB  1 
ATOM   8444 C  CG  . PRO B 1 554 ? 31.912  16.018  30.575  1   24.994 ? 546  PRO B CG  1 
ATOM   8445 C  CD  . PRO B 1 554 ? 31.101  15.422  31.748  1   25.553 ? 546  PRO B CD  1 
ATOM   8446 N  N   . ASP B 1 555 ? 34.657  15.196  32.84   1   26.176 ? 547  ASP B N   1 
ATOM   8447 C  CA  . ASP B 1 555 ? 35.94   15.547  33.442  1   28.789 ? 547  ASP B CA  1 
ATOM   8448 C  C   . ASP B 1 555 ? 36.37   14.6    34.555  1   30.106 ? 547  ASP B C   1 
ATOM   8449 O  O   . ASP B 1 555 ? 37.517  14.643  35.003  1   27.833 ? 547  ASP B O   1 
ATOM   8450 C  CB  . ASP B 1 555 ? 35.994  17.001  33.887  1   31.104 ? 547  ASP B CB  1 
ATOM   8451 C  CG  . ASP B 1 555 ? 35.755  18.024  32.78   1   33.746 ? 547  ASP B CG  1 
ATOM   8452 O  OD1 . ASP B 1 555 ? 36.198  17.808  31.629  1   41.121 ? 547  ASP B OD1 1 
ATOM   8453 O  OD2 . ASP B 1 555 ? 35.117  19.025  33.082  1   45.827 ? 547  ASP B OD2 1 
ATOM   8454 N  N   . ALA B 1 556 ? 35.471  13.728  35.018  1   23.904 ? 548  ALA B N   1 
ATOM   8455 C  CA  . ALA B 1 556 ? 35.766  12.829  36.109  1   23.863 ? 548  ALA B CA  1 
ATOM   8456 C  C   . ALA B 1 556 ? 36.665  11.679  35.645  1   24.12  ? 548  ALA B C   1 
ATOM   8457 O  O   . ALA B 1 556 ? 37.279  11.092  36.555  1   28.027 ? 548  ALA B O   1 
ATOM   8458 C  CB  . ALA B 1 556 ? 34.437  12.308  36.659  1   22.443 ? 548  ALA B CB  1 
ATOM   8459 O  OXT . ALA B 1 556 ? 36.709  11.374  34.431  1   24.181 ? 548  ALA B OXT 1 
HETATM 8460 C  C   . ACT C 2 .   ? 14.097  -2.958  44.805  1   16.318 ? 601  ACT A C   1 
HETATM 8461 O  O   . ACT C 2 .   ? 13.354  -2.806  45.798  1   15.322 ? 601  ACT A O   1 
HETATM 8462 O  OXT . ACT C 2 .   ? 14.372  -2.06   43.942  1   18.395 ? 601  ACT A OXT 1 
HETATM 8463 C  CH3 . ACT C 2 .   ? 14.67   -4.357  44.562  1   17.091 ? 601  ACT A CH3 1 
HETATM 8464 FE FE  . FE2 D 3 .   ? 12.889  -1.211  46.919  1   14.096 ? 602  FE2 A FE  1 
HETATM 8465 C  C   . ACT E 2 .   ? -20.044 -13.098 9.933   1   21.025 ? 601  ACT B C   1 
HETATM 8466 O  O   . ACT E 2 .   ? -19.266 -13.174 8.927   1   17.757 ? 601  ACT B O   1 
HETATM 8467 O  OXT . ACT E 2 .   ? -20.52  -12.04  10.364  1   22.107 ? 601  ACT B OXT 1 
HETATM 8468 C  CH3 . ACT E 2 .   ? -20.372 -14.416 10.643  1   19.45  ? 601  ACT B CH3 1 
HETATM 8469 FE FE  . FE2 F 3 .   ? -19.165 -11.989 7.244   1   17.617 ? 602  FE2 B FE  1 
HETATM 8470 O  O   . HOH G 4 .   ? 12.7    2.353   42.619  1   20.176 ? 701  HOH A O   1 
HETATM 8471 O  O   . HOH G 4 .   ? -7.99   13.171  29.913  1   32.654 ? 702  HOH A O   1 
HETATM 8472 O  O   . HOH G 4 .   ? -6.176  19.467  39.732  1   33.503 ? 703  HOH A O   1 
HETATM 8473 O  O   . HOH G 4 .   ? -17.639 -8.777  41.608  1   30.063 ? 704  HOH A O   1 
HETATM 8474 O  O   . HOH G 4 .   ? 10.919  -12.182 19.618  1   32.389 ? 705  HOH A O   1 
HETATM 8475 O  O   . HOH G 4 .   ? -11.795 8.61    39.821  1   23.819 ? 706  HOH A O   1 
HETATM 8476 O  O   . HOH G 4 .   ? -11.35  -18.905 56.969  1   40.528 ? 707  HOH A O   1 
HETATM 8477 O  O   . HOH G 4 .   ? 18.002  10.507  70.525  1   33.445 ? 708  HOH A O   1 
HETATM 8478 O  O   . HOH G 4 .   ? 2.763   -23.199 56.2    1   31.262 ? 709  HOH A O   1 
HETATM 8479 O  O   . HOH G 4 .   ? 16.894  3.059   80.226  1   44.015 ? 710  HOH A O   1 
HETATM 8480 O  O   . HOH G 4 .   ? 2.824   -27.841 13.292  1   39.727 ? 711  HOH A O   1 
HETATM 8481 O  O   . HOH G 4 .   ? 29.012  20.856  65.298  1   52.374 ? 712  HOH A O   1 
HETATM 8482 O  O   . HOH G 4 .   ? 14.715  -7.273  69.625  1   23.912 ? 713  HOH A O   1 
HETATM 8483 O  O   . HOH G 4 .   ? 21.807  22.015  48.476  1   29.894 ? 714  HOH A O   1 
HETATM 8484 O  O   . HOH G 4 .   ? 24.368  20.961  65.099  1   37.98  ? 715  HOH A O   1 
HETATM 8485 O  O   . HOH G 4 .   ? 25.848  -16.704 47.388  1   19.327 ? 716  HOH A O   1 
HETATM 8486 O  O   . HOH G 4 .   ? -17.425 -0.264  56.527  1   29.67  ? 717  HOH A O   1 
HETATM 8487 O  O   . HOH G 4 .   ? -7.645  -12.586 60.078  1   27.66  ? 718  HOH A O   1 
HETATM 8488 O  O   . HOH G 4 .   ? -2.732  -20.414 38.886  1   36.959 ? 719  HOH A O   1 
HETATM 8489 O  O   . HOH G 4 .   ? -29.903 1.823   11.587  1   20.815 ? 720  HOH A O   1 
HETATM 8490 O  O   . HOH G 4 .   ? 17.802  6.155   73.936  1   27.297 ? 721  HOH A O   1 
HETATM 8491 O  O   . HOH G 4 .   ? -9.368  10.969  33.11   1   35.773 ? 722  HOH A O   1 
HETATM 8492 O  O   . HOH G 4 .   ? 0.697   -27.316 47.328  1   38.727 ? 723  HOH A O   1 
HETATM 8493 O  O   . HOH G 4 .   ? 26.815  -8.024  67.593  1   32.489 ? 724  HOH A O   1 
HETATM 8494 O  O   . HOH G 4 .   ? 30.929  15.001  55.001  1   39.827 ? 725  HOH A O   1 
HETATM 8495 O  O   . HOH G 4 .   ? -1.974  0.463   67.196  1   26.525 ? 726  HOH A O   1 
HETATM 8496 O  O   . HOH G 4 .   ? -1.225  -4.492  66.63   1   20.023 ? 727  HOH A O   1 
HETATM 8497 O  O   . HOH G 4 .   ? -20.16  -3.956  35.689  1   22.588 ? 728  HOH A O   1 
HETATM 8498 O  O   . HOH G 4 .   ? -43.279 -0.477  17.303  1   19.928 ? 729  HOH A O   1 
HETATM 8499 O  O   . HOH G 4 .   ? 22.788  4.201   16.798  1   34.946 ? 730  HOH A O   1 
HETATM 8500 O  O   . HOH G 4 .   ? 14.696  8.594   38.885  1   14.086 ? 731  HOH A O   1 
HETATM 8501 O  O   . HOH G 4 .   ? 4.99    8       25.35   1   17.708 ? 732  HOH A O   1 
HETATM 8502 O  O   . HOH G 4 .   ? 20.338  -0.553  75      1   22.41  ? 733  HOH A O   1 
HETATM 8503 O  O   . HOH G 4 .   ? 28.48   1.503   73.965  1   40.792 ? 734  HOH A O   1 
HETATM 8504 O  O   . HOH G 4 .   ? 24.109  8.906   69.434  1   28.007 ? 735  HOH A O   1 
HETATM 8505 O  O   . HOH G 4 .   ? 33.868  -6.763  46.115  1   19.595 ? 736  HOH A O   1 
HETATM 8506 O  O   . HOH G 4 .   ? -16.091 2.932   39.523  1   40.087 ? 737  HOH A O   1 
HETATM 8507 O  O   . HOH G 4 .   ? -9.604  12.245  26.432  1   39.115 ? 738  HOH A O   1 
HETATM 8508 O  O   . HOH G 4 .   ? 19.781  -14.596 62.054  1   29.989 ? 739  HOH A O   1 
HETATM 8509 O  O   . HOH G 4 .   ? -12.968 -0.955  61.905  1   26.724 ? 740  HOH A O   1 
HETATM 8510 O  O   . HOH G 4 .   ? 31.789  -20.477 51.536  1   22.648 ? 741  HOH A O   1 
HETATM 8511 O  O   . HOH G 4 .   ? 10.52   -21.19  55.64   1   36.433 ? 742  HOH A O   1 
HETATM 8512 O  O   . HOH G 4 .   ? -10.706 -11.926 53.838  1   17.597 ? 743  HOH A O   1 
HETATM 8513 O  O   . HOH G 4 .   ? 34.451  -2.95   48.397  1   22.849 ? 744  HOH A O   1 
HETATM 8514 O  O   . HOH G 4 .   ? 32.355  -10.566 56.914  1   38.072 ? 745  HOH A O   1 
HETATM 8515 O  O   . HOH G 4 .   ? 26.916  19.781  55.668  1   26.278 ? 746  HOH A O   1 
HETATM 8516 O  O   . HOH G 4 .   ? 26.858  -16.195 51.486  1   21.93  ? 747  HOH A O   1 
HETATM 8517 O  O   . HOH G 4 .   ? 13.517  1.191   25.702  1   15.054 ? 748  HOH A O   1 
HETATM 8518 O  O   . HOH G 4 .   ? -4.275  -15.736 45.317  1   16.861 ? 749  HOH A O   1 
HETATM 8519 O  O   . HOH G 4 .   ? -9.151  8.273   52.886  1   38.076 ? 750  HOH A O   1 
HETATM 8520 O  O   . HOH G 4 .   ? 1.59    14.71   53.186  1   20.539 ? 751  HOH A O   1 
HETATM 8521 O  O   . HOH G 4 .   ? 8.991   -9.088  41.129  1   16.368 ? 752  HOH A O   1 
HETATM 8522 O  O   . HOH G 4 .   ? 4.999   5.134   71.05   1   27.143 ? 753  HOH A O   1 
HETATM 8523 O  O   . HOH G 4 .   ? -9.080  14.548  45.938  1   32.397 ? 754  HOH A O   1 
HETATM 8524 O  O   . HOH G 4 .   ? 33.761  4.234   48.265  1   24.055 ? 755  HOH A O   1 
HETATM 8525 O  O   . HOH G 4 .   ? -5.189  -19.646 48.514  1   27.219 ? 756  HOH A O   1 
HETATM 8526 O  O   . HOH G 4 .   ? -1.495  -11.897 71.658  1   42.615 ? 757  HOH A O   1 
HETATM 8527 O  O   . HOH G 4 .   ? 4.823   -20.762 43.098  1   31.932 ? 758  HOH A O   1 
HETATM 8528 O  O   . HOH G 4 .   ? 6.433   13.529  25.158  1   25.015 ? 759  HOH A O   1 
HETATM 8529 O  O   . HOH G 4 .   ? -15.277 -14.439 50.553  1   50.123 ? 760  HOH A O   1 
HETATM 8530 O  O   . HOH G 4 .   ? 2.258   20.874  44.884  1   35.304 ? 761  HOH A O   1 
HETATM 8531 O  O   . HOH G 4 .   ? 10.207  -17.499 40.155  1   34.098 ? 762  HOH A O   1 
HETATM 8532 O  O   . HOH G 4 .   ? 28.11   -12.766 54.91   1   24.638 ? 763  HOH A O   1 
HETATM 8533 O  O   . HOH G 4 .   ? 6.765   -24.864 20.556  1   33.2   ? 764  HOH A O   1 
HETATM 8534 O  O   . HOH G 4 .   ? 7.662   -4.926  61.482  1   13.839 ? 765  HOH A O   1 
HETATM 8535 O  O   . HOH G 4 .   ? 7.162   -11.932 34.841  1   24.69  ? 766  HOH A O   1 
HETATM 8536 O  O   . HOH G 4 .   ? 3.956   12.179  24.715  1   24.321 ? 767  HOH A O   1 
HETATM 8537 O  O   . HOH G 4 .   ? 31.321  19.014  46.633  1   31.594 ? 768  HOH A O   1 
HETATM 8538 O  O   . HOH G 4 .   ? 10.28   22.348  46.341  1   29.433 ? 769  HOH A O   1 
HETATM 8539 O  O   . HOH G 4 .   ? 1.738   19.015  38.01   1   34.458 ? 770  HOH A O   1 
HETATM 8540 O  O   . HOH G 4 .   ? 23.772  13.651  67.164  1   39.089 ? 771  HOH A O   1 
HETATM 8541 O  O   . HOH G 4 .   ? 14.257  -12.405 53.862  1   15.732 ? 772  HOH A O   1 
HETATM 8542 O  O   . HOH G 4 .   ? 4.04    2.582   51.744  1   16.7   ? 773  HOH A O   1 
HETATM 8543 O  O   . HOH G 4 .   ? 12.565  -2.091  72.474  1   23.483 ? 774  HOH A O   1 
HETATM 8544 O  O   . HOH G 4 .   ? 7.716   5.075   50.034  1   23.546 ? 775  HOH A O   1 
HETATM 8545 O  O   . HOH G 4 .   ? 19.448  19.076  66.075  1   43.812 ? 776  HOH A O   1 
HETATM 8546 O  O   . HOH G 4 .   ? 5.816   -12.409 40.965  1   16.961 ? 777  HOH A O   1 
HETATM 8547 O  O   . HOH G 4 .   ? 39.415  -10.815 48.45   1   39.295 ? 778  HOH A O   1 
HETATM 8548 O  O   . HOH G 4 .   ? 21.428  -10.649 32.225  1   28.735 ? 779  HOH A O   1 
HETATM 8549 O  O   . HOH G 4 .   ? -3.666  -11.294 66.252  1   35.859 ? 780  HOH A O   1 
HETATM 8550 O  O   . HOH G 4 .   ? 17.264  0.783   41.103  1   15.047 ? 781  HOH A O   1 
HETATM 8551 O  O   . HOH G 4 .   ? -12.528 17.072  36.063  1   37.93  ? 782  HOH A O   1 
HETATM 8552 O  O   . HOH G 4 .   ? -2.296  16.741  33.259  1   30.43  ? 783  HOH A O   1 
HETATM 8553 O  O   . HOH G 4 .   ? 3.437   19.973  58.656  1   31.508 ? 784  HOH A O   1 
HETATM 8554 O  O   . HOH G 4 .   ? 12.136  20.898  38.112  1   28.053 ? 785  HOH A O   1 
HETATM 8555 O  O   . HOH G 4 .   ? 15.724  2.657   42.744  1   15.77  ? 786  HOH A O   1 
HETATM 8556 O  O   . HOH G 4 .   ? 7.545   -11.289 67.33   1   23.573 ? 787  HOH A O   1 
HETATM 8557 O  O   . HOH G 4 .   ? 3.904   8.577   30.679  1   13.951 ? 788  HOH A O   1 
HETATM 8558 O  O   . HOH G 4 .   ? 26.251  -14.715 49.274  1   18.853 ? 789  HOH A O   1 
HETATM 8559 O  O   . HOH G 4 .   ? 21.734  1.622   42.842  1   14.345 ? 790  HOH A O   1 
HETATM 8560 O  O   . HOH G 4 .   ? -8.283  -16.6   59.754  1   35.415 ? 791  HOH A O   1 
HETATM 8561 O  O   . HOH G 4 .   ? 26.147  -2.104  36.935  1   14.265 ? 792  HOH A O   1 
HETATM 8562 O  O   . HOH G 4 .   ? -13.487 5.349   61.423  1   39.34  ? 793  HOH A O   1 
HETATM 8563 O  O   . HOH G 4 .   ? -11.215 4.898   37.013  1   15.14  ? 794  HOH A O   1 
HETATM 8564 O  O   . HOH G 4 .   ? -14.873 3.335   54.916  1   28.57  ? 795  HOH A O   1 
HETATM 8565 O  O   . HOH G 4 .   ? -2.373  -4.05   64.121  1   21.083 ? 796  HOH A O   1 
HETATM 8566 O  O   . HOH G 4 .   ? 15.481  -6.983  32.299  1   19.026 ? 797  HOH A O   1 
HETATM 8567 O  O   . HOH G 4 .   ? -10.696 0.94    27.94   1   13.07  ? 798  HOH A O   1 
HETATM 8568 O  O   . HOH G 4 .   ? -19.308 -3.691  46.017  1   38.439 ? 799  HOH A O   1 
HETATM 8569 O  O   . HOH G 4 .   ? 6.383   18.218  36.266  1   24.61  ? 800  HOH A O   1 
HETATM 8570 O  O   . HOH G 4 .   ? -3.722  -22.399 41.132  1   47.551 ? 801  HOH A O   1 
HETATM 8571 O  O   . HOH G 4 .   ? 15.805  8.837   70.812  1   38.966 ? 802  HOH A O   1 
HETATM 8572 O  O   . HOH G 4 .   ? 1.486   -6.556  44.421  1   12.081 ? 803  HOH A O   1 
HETATM 8573 O  O   . HOH G 4 .   ? 27.702  -21.613 40.715  1   33.216 ? 804  HOH A O   1 
HETATM 8574 O  O   . HOH G 4 .   ? -5.889  15.723  38.282  1   16.943 ? 805  HOH A O   1 
HETATM 8575 O  O   . HOH G 4 .   ? -3.05   -19.499 55.031  1   24.914 ? 806  HOH A O   1 
HETATM 8576 O  O   . HOH G 4 .   ? 16.593  -18.483 42.186  1   32.209 ? 807  HOH A O   1 
HETATM 8577 O  O   . HOH G 4 .   ? 10.209  -5.976  28.352  1   16.737 ? 808  HOH A O   1 
HETATM 8578 O  O   . HOH G 4 .   ? 12.753  4.398   31.156  1   12.912 ? 809  HOH A O   1 
HETATM 8579 O  O   . HOH G 4 .   ? 4.925   -0.365  23.729  1   15.552 ? 810  HOH A O   1 
HETATM 8580 O  O   . HOH G 4 .   ? -44.806 8.459   16.782  1   35.328 ? 811  HOH A O   1 
HETATM 8581 O  O   . HOH G 4 .   ? 27.631  0.548   65.77   1   16.432 ? 812  HOH A O   1 
HETATM 8582 O  O   . HOH G 4 .   ? 11.656  -6.849  33.289  1   29.286 ? 813  HOH A O   1 
HETATM 8583 O  O   . HOH G 4 .   ? 12.948  13.907  42.994  1   13.217 ? 814  HOH A O   1 
HETATM 8584 O  O   . HOH G 4 .   ? 8.416   -3.08   50.418  1   12.679 ? 815  HOH A O   1 
HETATM 8585 O  O   . HOH G 4 .   ? 31.387  17.178  48.499  1   36.106 ? 816  HOH A O   1 
HETATM 8586 O  O   . HOH G 4 .   ? -10.49  0.804   52.475  1   17.51  ? 817  HOH A O   1 
HETATM 8587 O  O   . HOH G 4 .   ? 19.161  -0.042  51.858  1   14.369 ? 818  HOH A O   1 
HETATM 8588 O  O   . HOH G 4 .   ? 16.596  -5.996  68.183  1   16.883 ? 819  HOH A O   1 
HETATM 8589 O  O   . HOH G 4 .   ? 29.474  3.044   23.729  1   27.165 ? 820  HOH A O   1 
HETATM 8590 O  O   . HOH G 4 .   ? -4.918  -5.949  66.279  1   28.596 ? 821  HOH A O   1 
HETATM 8591 O  O   . HOH G 4 .   ? 27.986  16.281  50.939  1   20.369 ? 822  HOH A O   1 
HETATM 8592 O  O   . HOH G 4 .   ? -16.276 -8.034  49.885  1   27.433 ? 823  HOH A O   1 
HETATM 8593 O  O   . HOH G 4 .   ? -15.1   -3.686  37.708  1   13.391 ? 824  HOH A O   1 
HETATM 8594 O  O   . HOH G 4 .   ? 13.178  -11.384 27.555  1   29.077 ? 825  HOH A O   1 
HETATM 8595 O  O   . HOH G 4 .   ? 15.85   9.086   32.046  1   13.115 ? 826  HOH A O   1 
HETATM 8596 O  O   . HOH G 4 .   ? -5.948  3.663   63.786  1   33.922 ? 827  HOH A O   1 
HETATM 8597 O  O   . HOH G 4 .   ? -24.792 8.318   25.04   1   22.646 ? 828  HOH A O   1 
HETATM 8598 O  O   . HOH G 4 .   ? -1.525  -17.944 61.808  1   30.528 ? 829  HOH A O   1 
HETATM 8599 O  O   . HOH G 4 .   ? 4.175   18.873  31.088  1   20.871 ? 830  HOH A O   1 
HETATM 8600 O  O   . HOH G 4 .   ? 8.646   -20.662 46.656  1   26.201 ? 831  HOH A O   1 
HETATM 8601 O  O   . HOH G 4 .   ? 17.726  -9.871  33.062  1   22.078 ? 832  HOH A O   1 
HETATM 8602 O  O   . HOH G 4 .   ? 4.153   6.482   27.491  1   17.48  ? 833  HOH A O   1 
HETATM 8603 O  O   . HOH G 4 .   ? -13.453 -15.096 55.752  1   39.109 ? 834  HOH A O   1 
HETATM 8604 O  O   . HOH G 4 .   ? 29.538  -6.684  40.413  1   16.696 ? 835  HOH A O   1 
HETATM 8605 O  O   . HOH G 4 .   ? 24.102  6.064   38.404  1   15.514 ? 836  HOH A O   1 
HETATM 8606 O  O   . HOH G 4 .   ? 22.783  10.496  65.093  1   18.226 ? 837  HOH A O   1 
HETATM 8607 O  O   . HOH G 4 .   ? 18.452  13.581  30.203  1   16.189 ? 838  HOH A O   1 
HETATM 8608 O  O   . HOH G 4 .   ? -14.325 -14.43  35.975  1   26.635 ? 839  HOH A O   1 
HETATM 8609 O  O   . HOH G 4 .   ? -1.151  2.043   52.029  1   14.817 ? 840  HOH A O   1 
HETATM 8610 O  O   . HOH G 4 .   ? 19.99   -1.069  29.005  1   15.542 ? 841  HOH A O   1 
HETATM 8611 O  O   . HOH G 4 .   ? 30.843  -5.736  31.542  1   21.984 ? 842  HOH A O   1 
HETATM 8612 O  O   . HOH G 4 .   ? 10.164  -22.868 11.093  1   35.748 ? 843  HOH A O   1 
HETATM 8613 O  O   . HOH G 4 .   ? 6.856   4.009   61.594  1   14.798 ? 844  HOH A O   1 
HETATM 8614 O  O   . HOH G 4 .   ? 6.207   -10.612 32.085  1   20.263 ? 845  HOH A O   1 
HETATM 8615 O  O   . HOH G 4 .   ? -6.093  7.322   44.013  1   15.38  ? 846  HOH A O   1 
HETATM 8616 O  O   . HOH G 4 .   ? 15.581  -12.055 39.797  1   30.246 ? 847  HOH A O   1 
HETATM 8617 O  O   . HOH G 4 .   ? 23.414  18.475  42.003  1   28.089 ? 848  HOH A O   1 
HETATM 8618 O  O   . HOH G 4 .   ? 14.312  0.233   12.185  1   43.832 ? 849  HOH A O   1 
HETATM 8619 O  O   . HOH G 4 .   ? 21.605  15.896  67.322  1   29.93  ? 850  HOH A O   1 
HETATM 8620 O  O   . HOH G 4 .   ? 25.713  -9.471  35.839  1   21.9   ? 851  HOH A O   1 
HETATM 8621 O  O   . HOH G 4 .   ? 1.007   2.89    69.223  1   46.042 ? 852  HOH A O   1 
HETATM 8622 O  O   . HOH G 4 .   ? -9.703  20.6    38.617  1   32.832 ? 853  HOH A O   1 
HETATM 8623 O  O   . HOH G 4 .   ? -8.949  -6.854  61.16   1   22.294 ? 854  HOH A O   1 
HETATM 8624 O  O   . HOH G 4 .   ? 23.154  -8.254  35.362  1   36.424 ? 855  HOH A O   1 
HETATM 8625 O  O   . HOH G 4 .   ? 13      15.702  66.063  1   45.897 ? 856  HOH A O   1 
HETATM 8626 O  O   . HOH G 4 .   ? 1.567   -0.623  60.711  1   13.954 ? 857  HOH A O   1 
HETATM 8627 O  O   . HOH G 4 .   ? -14.016 0.827   59.951  1   27.738 ? 858  HOH A O   1 
HETATM 8628 O  O   . HOH G 4 .   ? -45.582 -2.598  11.399  1   30.695 ? 859  HOH A O   1 
HETATM 8629 O  O   . HOH G 4 .   ? 3.141   -5.824  39.138  1   17.44  ? 860  HOH A O   1 
HETATM 8630 O  O   . HOH G 4 .   ? -5.342  16.218  35.784  1   28.499 ? 861  HOH A O   1 
HETATM 8631 O  O   . HOH G 4 .   ? 1.909   4.982   67.526  1   23.417 ? 862  HOH A O   1 
HETATM 8632 O  O   . HOH G 4 .   ? 32.864  3.018   63.899  1   41.575 ? 863  HOH A O   1 
HETATM 8633 O  O   . HOH G 4 .   ? -6.946  -17.809 47.611  1   21.674 ? 864  HOH A O   1 
HETATM 8634 O  O   . HOH G 4 .   ? 10.479  0.071   52.706  1   13.763 ? 865  HOH A O   1 
HETATM 8635 O  O   . HOH G 4 .   ? -16.388 -12.493 48.781  1   27.321 ? 866  HOH A O   1 
HETATM 8636 O  O   . HOH G 4 .   ? 31.777  15.018  45.563  1   26.74  ? 867  HOH A O   1 
HETATM 8637 O  O   . HOH G 4 .   ? -8.451  4.437   26.955  1   25.16  ? 868  HOH A O   1 
HETATM 8638 O  O   . HOH G 4 .   ? 35.769  1.616   51.265  1   27.099 ? 869  HOH A O   1 
HETATM 8639 O  O   . HOH G 4 .   ? -46.940 0.532   17.651  1   28.271 ? 870  HOH A O   1 
HETATM 8640 O  O   . HOH G 4 .   ? 21.672  -22.462 49.124  1   34.12  ? 871  HOH A O   1 
HETATM 8641 O  O   . HOH G 4 .   ? 10.19   7.414   72.758  1   37.575 ? 872  HOH A O   1 
HETATM 8642 O  O   . HOH G 4 .   ? 6.047   20.42   57.892  1   23.925 ? 873  HOH A O   1 
HETATM 8643 O  O   . HOH G 4 .   ? -1.353  14.79   40.646  1   16.459 ? 874  HOH A O   1 
HETATM 8644 O  O   . HOH G 4 .   ? 14.884  12.178  25.749  1   15.859 ? 875  HOH A O   1 
HETATM 8645 O  O   . HOH G 4 .   ? 14.891  12.345  18.196  1   50.341 ? 876  HOH A O   1 
HETATM 8646 O  O   . HOH G 4 .   ? -32.051 8.472   8.116   1   26.006 ? 877  HOH A O   1 
HETATM 8647 O  O   . HOH G 4 .   ? 9.944   -16.223 31.431  1   33.519 ? 878  HOH A O   1 
HETATM 8648 O  O   . HOH G 4 .   ? 10.003  4.077   31.169  1   12.438 ? 879  HOH A O   1 
HETATM 8649 O  O   . HOH G 4 .   ? 9.776   1.977   22.943  1   13.857 ? 880  HOH A O   1 
HETATM 8650 O  O   . HOH G 4 .   ? 18.682  -4.089  18.557  1   47.3   ? 881  HOH A O   1 
HETATM 8651 O  O   . HOH G 4 .   ? 7.735   4.875   72.343  1   30.897 ? 882  HOH A O   1 
HETATM 8652 O  O   . HOH G 4 .   ? 14.55   -18.789 56.826  1   29.943 ? 883  HOH A O   1 
HETATM 8653 O  O   . HOH G 4 .   ? -6.467  -4.658  63.387  1   44.04  ? 884  HOH A O   1 
HETATM 8654 O  O   . HOH G 4 .   ? 37.11   -18.055 48.238  1   29.349 ? 885  HOH A O   1 
HETATM 8655 O  O   . HOH G 4 .   ? 10.038  1.784   55.949  1   12.092 ? 886  HOH A O   1 
HETATM 8656 O  O   . HOH G 4 .   ? 31.012  -21.892 37.666  1   22.184 ? 887  HOH A O   1 
HETATM 8657 O  O   . HOH G 4 .   ? 15.825  3.753   46.629  1   13.67  ? 888  HOH A O   1 
HETATM 8658 O  O   . HOH G 4 .   ? 2.291   -10.043 37.383  1   19.058 ? 889  HOH A O   1 
HETATM 8659 O  O   . HOH G 4 .   ? 16.738  -12.153 37.263  1   26.558 ? 890  HOH A O   1 
HETATM 8660 O  O   . HOH G 4 .   ? -2.95   2.995   56.038  1   15.424 ? 891  HOH A O   1 
HETATM 8661 O  O   . HOH G 4 .   ? -2.953  13.932  30.5    1   23.578 ? 892  HOH A O   1 
HETATM 8662 O  O   . HOH G 4 .   ? -36.679 6.988   14.387  1   35.703 ? 893  HOH A O   1 
HETATM 8663 O  O   . HOH G 4 .   ? 28.759  -24.428 49.679  1   28.167 ? 894  HOH A O   1 
HETATM 8664 O  O   . HOH G 4 .   ? 1.114   14.647  39.234  1   13.839 ? 895  HOH A O   1 
HETATM 8665 O  O   . HOH G 4 .   ? 26.852  -2.746  54.296  1   26.299 ? 896  HOH A O   1 
HETATM 8666 O  O   . HOH G 4 .   ? 21.045  21.682  57.899  1   29.555 ? 897  HOH A O   1 
HETATM 8667 O  O   . HOH G 4 .   ? -16.939 -5.637  38.576  1   22.015 ? 898  HOH A O   1 
HETATM 8668 O  O   . HOH G 4 .   ? -5.342  -3.248  65.686  1   31.044 ? 899  HOH A O   1 
HETATM 8669 O  O   . HOH G 4 .   ? 12.835  -0.147  45.18   1   17.827 ? 900  HOH A O   1 
HETATM 8670 O  O   . HOH G 4 .   ? 4.734   21.145  44.478  1   31.375 ? 901  HOH A O   1 
HETATM 8671 O  O   . HOH G 4 .   ? 18.721  -0.251  26.654  1   14.752 ? 902  HOH A O   1 
HETATM 8672 O  O   . HOH G 4 .   ? 16.797  -1.329  42.868  1   23.011 ? 903  HOH A O   1 
HETATM 8673 O  O   . HOH G 4 .   ? 26.197  -2.72   71.093  1   30.817 ? 904  HOH A O   1 
HETATM 8674 O  O   . HOH G 4 .   ? 22.015  7.067   43.944  1   12.161 ? 905  HOH A O   1 
HETATM 8675 O  O   . HOH G 4 .   ? 4.302   7.05    50.774  1   19.882 ? 906  HOH A O   1 
HETATM 8676 O  O   . HOH G 4 .   ? 33.249  -8.812  39.433  1   28.743 ? 907  HOH A O   1 
HETATM 8677 O  O   . HOH G 4 .   ? -0.393  17.767  50.723  1   19.319 ? 908  HOH A O   1 
HETATM 8678 O  O   . HOH G 4 .   ? -14.732 -2.216  28.867  1   14.238 ? 909  HOH A O   1 
HETATM 8679 O  O   . HOH G 4 .   ? -41.656 -0.049  22.448  1   28.191 ? 910  HOH A O   1 
HETATM 8680 O  O   . HOH G 4 .   ? 33.086  9.486   53.827  1   26.445 ? 911  HOH A O   1 
HETATM 8681 O  O   . HOH G 4 .   ? -12.326 17.662  40.334  1   21.709 ? 912  HOH A O   1 
HETATM 8682 O  O   . HOH G 4 .   ? 24.3    -14.881 45.871  1   21.1   ? 913  HOH A O   1 
HETATM 8683 O  O   . HOH G 4 .   ? 3.969   -0.724  29.449  1   17.353 ? 914  HOH A O   1 
HETATM 8684 O  O   . HOH G 4 .   ? 11.588  16.389  42.812  1   13.23  ? 915  HOH A O   1 
HETATM 8685 O  O   . HOH G 4 .   ? 21.654  -3.307  31.247  1   20.799 ? 916  HOH A O   1 
HETATM 8686 O  O   . HOH G 4 .   ? 7.665   19.989  32.948  1   25.104 ? 917  HOH A O   1 
HETATM 8687 O  O   . HOH G 4 .   ? 17.898  19.871  58.598  1   21.995 ? 918  HOH A O   1 
HETATM 8688 O  O   . HOH G 4 .   ? 20.958  0.186   32.373  1   15.787 ? 919  HOH A O   1 
HETATM 8689 O  O   . HOH G 4 .   ? 26.843  -13.029 38.737  1   28.712 ? 920  HOH A O   1 
HETATM 8690 O  O   . HOH G 4 .   ? 15.905  15.692  65.738  1   39.013 ? 921  HOH A O   1 
HETATM 8691 O  O   . HOH G 4 .   ? 31.42   1.472   26.344  1   22.314 ? 922  HOH A O   1 
HETATM 8692 O  O   . HOH G 4 .   ? 4.49    -11.95  34.194  1   35.645 ? 923  HOH A O   1 
HETATM 8693 O  O   . HOH G 4 .   ? -16.483 12.845  27.616  1   37.42  ? 924  HOH A O   1 
HETATM 8694 O  O   . HOH G 4 .   ? -5.115  -10.088 59.558  1   20.244 ? 925  HOH A O   1 
HETATM 8695 O  O   . HOH G 4 .   ? 10.51   -6.831  38.976  1   16.007 ? 926  HOH A O   1 
HETATM 8696 O  O   . HOH G 4 .   ? 28.006  14.447  37.576  1   30.12  ? 927  HOH A O   1 
HETATM 8697 O  O   . HOH G 4 .   ? 0.566   -0.682  52.932  1   13.82  ? 928  HOH A O   1 
HETATM 8698 O  O   . HOH G 4 .   ? 3.923   -6.78   72.764  1   49.877 ? 929  HOH A O   1 
HETATM 8699 O  O   . HOH G 4 .   ? -13.515 9.266   33.586  1   42.395 ? 930  HOH A O   1 
HETATM 8700 O  O   . HOH G 4 .   ? 1.392   0.898   66.989  1   19.14  ? 931  HOH A O   1 
HETATM 8701 O  O   . HOH G 4 .   ? 3.08    -24.013 43.509  1   43.664 ? 932  HOH A O   1 
HETATM 8702 O  O   . HOH G 4 .   ? 6.089   -9.333  69.748  1   31.322 ? 933  HOH A O   1 
HETATM 8703 O  O   . HOH G 4 .   ? 32.593  10.515  56.64   1   35.637 ? 934  HOH A O   1 
HETATM 8704 O  O   . HOH G 4 .   ? -0.723  1.687   54.695  1   14.921 ? 935  HOH A O   1 
HETATM 8705 O  O   . HOH G 4 .   ? 7.267   11.142  62.841  1   16.385 ? 936  HOH A O   1 
HETATM 8706 O  O   . HOH G 4 .   ? 11.063  -22.484 52.026  1   38.242 ? 937  HOH A O   1 
HETATM 8707 O  O   . HOH G 4 .   ? 21.524  2.68    33.925  1   15.091 ? 938  HOH A O   1 
HETATM 8708 O  O   . HOH G 4 .   ? 18.236  4.501   15.28   1   32.687 ? 939  HOH A O   1 
HETATM 8709 O  O   . HOH G 4 .   ? 39.928  -19.271 38.869  1   36.804 ? 940  HOH A O   1 
HETATM 8710 O  O   . HOH G 4 .   ? -16.247 -3.894  56.237  1   23.585 ? 941  HOH A O   1 
HETATM 8711 O  O   . HOH G 4 .   ? 8.733   -33.952 21.997  1   67.04  ? 942  HOH A O   1 
HETATM 8712 O  O   . HOH G 4 .   ? 22.981  -4.133  34.327  1   15.389 ? 943  HOH A O   1 
HETATM 8713 O  O   . HOH G 4 .   ? 16.437  23.574  45.483  1   32.038 ? 944  HOH A O   1 
HETATM 8714 O  O   . HOH G 4 .   ? -14.937 0.024   45.836  1   18.579 ? 945  HOH A O   1 
HETATM 8715 O  O   . HOH G 4 .   ? 16.337  -1.057  25.526  1   16.378 ? 946  HOH A O   1 
HETATM 8716 O  O   . HOH G 4 .   ? -11.513 -16.769 48.083  1   21.678 ? 947  HOH A O   1 
HETATM 8717 O  O   . HOH G 4 .   ? 32.978  11.173  47.037  1   23.26  ? 948  HOH A O   1 
HETATM 8718 O  O   . HOH G 4 .   ? 0.795   1.481   50.089  1   13.43  ? 949  HOH A O   1 
HETATM 8719 O  O   . HOH G 4 .   ? 17.894  -15.799 50.145  1   18.03  ? 950  HOH A O   1 
HETATM 8720 O  O   . HOH G 4 .   ? 2.66    -3.378  45.701  1   12.575 ? 951  HOH A O   1 
HETATM 8721 O  O   . HOH G 4 .   ? 7.476   -13.517 65.661  1   26.771 ? 952  HOH A O   1 
HETATM 8722 O  O   . HOH G 4 .   ? -4.542  -18.773 52.297  1   20.851 ? 953  HOH A O   1 
HETATM 8723 O  O   . HOH G 4 .   ? 8.633   -14.319 43.752  1   16.156 ? 954  HOH A O   1 
HETATM 8724 O  O   . HOH G 4 .   ? 9.423   -18.003 62.265  1   30.889 ? 955  HOH A O   1 
HETATM 8725 O  O   . HOH G 4 .   ? 4.63    -14.284 65.268  1   30.102 ? 956  HOH A O   1 
HETATM 8726 O  O   . HOH G 4 .   ? 5.409   -1.727  72.425  1   45.054 ? 957  HOH A O   1 
HETATM 8727 O  O   . HOH G 4 .   ? 17.553  21.567  41.229  1   20.026 ? 958  HOH A O   1 
HETATM 8728 O  O   . HOH G 4 .   ? 8.337   13.705  16.988  1   35.84  ? 959  HOH A O   1 
HETATM 8729 O  O   . HOH G 4 .   ? 25.256  7.979   40.228  1   13.69  ? 960  HOH A O   1 
HETATM 8730 O  O   . HOH G 4 .   ? 12.521  -24.869 51.298  1   42.961 ? 961  HOH A O   1 
HETATM 8731 O  O   . HOH G 4 .   ? 16.092  1.594   28.59   1   14.501 ? 962  HOH A O   1 
HETATM 8732 O  O   . HOH G 4 .   ? -15.489 3.674   46.608  1   17.407 ? 963  HOH A O   1 
HETATM 8733 O  O   . HOH G 4 .   ? -0.062  8.813   56.959  1   35.131 ? 964  HOH A O   1 
HETATM 8734 O  O   . HOH G 4 .   ? 14.367  -5.175  33.961  1   13.889 ? 965  HOH A O   1 
HETATM 8735 O  O   . HOH G 4 .   ? 19.2    -6.462  68.823  1   20.757 ? 966  HOH A O   1 
HETATM 8736 O  O   . HOH G 4 .   ? 6.493   -12.501 43.669  1   14.483 ? 967  HOH A O   1 
HETATM 8737 O  O   . HOH G 4 .   ? 26.035  -1.796  20.123  1   24.473 ? 968  HOH A O   1 
HETATM 8738 O  O   . HOH G 4 .   ? -19.154 -2.783  53.275  1   38.753 ? 969  HOH A O   1 
HETATM 8739 O  O   . HOH G 4 .   ? -12.885 -5.465  61.762  1   31.46  ? 970  HOH A O   1 
HETATM 8740 O  O   . HOH G 4 .   ? 32.203  -9.525  29.198  1   36.786 ? 971  HOH A O   1 
HETATM 8741 O  O   . HOH G 4 .   ? 24.77   -6.16   28.91   1   18.818 ? 972  HOH A O   1 
HETATM 8742 O  O   . HOH G 4 .   ? -14.759 11.104  31.397  1   33.689 ? 973  HOH A O   1 
HETATM 8743 O  O   . HOH G 4 .   ? -13.476 10.761  25.38   1   39.571 ? 974  HOH A O   1 
HETATM 8744 O  O   . HOH G 4 .   ? 26.969  -11.908 59.346  1   28.92  ? 975  HOH A O   1 
HETATM 8745 O  O   . HOH G 4 .   ? 26.735  0.759   69.435  1   23.419 ? 976  HOH A O   1 
HETATM 8746 O  O   . HOH G 4 .   ? 17.965  5.453   47.628  1   13.484 ? 977  HOH A O   1 
HETATM 8747 O  O   . HOH G 4 .   ? 15.539  -17.113 49.539  1   18.727 ? 978  HOH A O   1 
HETATM 8748 O  O   . HOH G 4 .   ? -22.991 13.675  17.289  1   33.21  ? 979  HOH A O   1 
HETATM 8749 O  O   . HOH G 4 .   ? 15.338  -16.077 35.232  1   26.768 ? 980  HOH A O   1 
HETATM 8750 O  O   . HOH G 4 .   ? 34.402  0.601   65.228  1   40.756 ? 981  HOH A O   1 
HETATM 8751 O  O   . HOH G 4 .   ? 9.773   -2.477  64.156  1   18.65  ? 982  HOH A O   1 
HETATM 8752 O  O   . HOH G 4 .   ? 30.845  -9.533  58.869  1   23.862 ? 983  HOH A O   1 
HETATM 8753 O  O   . HOH G 4 .   ? 4.108   1.069   54.126  1   16.362 ? 984  HOH A O   1 
HETATM 8754 O  O   . HOH G 4 .   ? 10.566  14.772  15.454  1   39.439 ? 985  HOH A O   1 
HETATM 8755 O  O   . HOH G 4 .   ? 21.901  -0.731  70.268  1   19.604 ? 986  HOH A O   1 
HETATM 8756 O  O   . HOH G 4 .   ? -0.326  10.924  49.965  1   20.792 ? 987  HOH A O   1 
HETATM 8757 O  O   . HOH G 4 .   ? 5.702   5.788   48.406  1   15.501 ? 988  HOH A O   1 
HETATM 8758 O  O   . HOH G 4 .   ? 4.168   13.611  27.962  1   18.154 ? 989  HOH A O   1 
HETATM 8759 O  O   . HOH G 4 .   ? 25.077  -14.393 58.396  1   35.654 ? 990  HOH A O   1 
HETATM 8760 O  O   . HOH G 4 .   ? 14.805  -3.698  71.592  1   20.725 ? 991  HOH A O   1 
HETATM 8761 O  O   . HOH G 4 .   ? 30.485  -15.075 42.051  1   26.03  ? 992  HOH A O   1 
HETATM 8762 O  O   . HOH G 4 .   ? -12.469 4.552   52.325  1   45.132 ? 993  HOH A O   1 
HETATM 8763 O  O   . HOH G 4 .   ? 18.359  0.979   34.516  1   14.407 ? 994  HOH A O   1 
HETATM 8764 O  O   . HOH G 4 .   ? 5.878   -7.51   24.234  1   17.945 ? 995  HOH A O   1 
HETATM 8765 O  O   . HOH G 4 .   ? 8.828   22.815  43.201  1   44.372 ? 996  HOH A O   1 
HETATM 8766 O  O   . HOH G 4 .   ? -32.964 12.816  9.769   1   41.125 ? 997  HOH A O   1 
HETATM 8767 O  O   . HOH G 4 .   ? 21.237  -10.079 35.476  1   33.257 ? 998  HOH A O   1 
HETATM 8768 O  O   . HOH G 4 .   ? 19.869  -10.722 69.562  1   41.296 ? 999  HOH A O   1 
HETATM 8769 O  O   . HOH G 4 .   ? -39.222 0.485   11.337  1   33.898 ? 1000 HOH A O   1 
HETATM 8770 O  O   . HOH G 4 .   ? 22.455  -2.767  26.731  1   16.695 ? 1001 HOH A O   1 
HETATM 8771 O  O   . HOH G 4 .   ? -40.363 3.883   22.444  1   30.371 ? 1002 HOH A O   1 
HETATM 8772 O  O   . HOH G 4 .   ? 16.64   9.123   19.801  1   20.601 ? 1003 HOH A O   1 
HETATM 8773 O  O   . HOH G 4 .   ? 2.306   15.266  23.967  1   42.998 ? 1004 HOH A O   1 
HETATM 8774 O  O   . HOH G 4 .   ? 30.804  0.646   58.69   1   19.337 ? 1005 HOH A O   1 
HETATM 8775 O  O   . HOH G 4 .   ? 10.959  5.286   16.257  1   25.139 ? 1006 HOH A O   1 
HETATM 8776 O  O   . HOH G 4 .   ? 17.4    -2.295  20.379  1   17.518 ? 1007 HOH A O   1 
HETATM 8777 O  O   . HOH G 4 .   ? 11.481  24.143  48.258  1   25.663 ? 1008 HOH A O   1 
HETATM 8778 O  O   . HOH G 4 .   ? -16.712 -6.216  34.035  1   20.405 ? 1009 HOH A O   1 
HETATM 8779 O  O   . HOH G 4 .   ? 3.125   7.23    54.86   1   18.196 ? 1010 HOH A O   1 
HETATM 8780 O  O   . HOH G 4 .   ? 8.268   6.182   68.459  1   22.191 ? 1011 HOH A O   1 
HETATM 8781 O  O   . HOH G 4 .   ? 5.361   -13.84  69.509  1   48     ? 1012 HOH A O   1 
HETATM 8782 O  O   . HOH G 4 .   ? 20.252  -12.612 26.807  1   41.573 ? 1013 HOH A O   1 
HETATM 8783 O  O   . HOH G 4 .   ? 32.969  -18.868 53.414  1   28.221 ? 1014 HOH A O   1 
HETATM 8784 O  O   . HOH G 4 .   ? 5.881   -4.812  63.492  1   16.651 ? 1015 HOH A O   1 
HETATM 8785 O  O   . HOH G 4 .   ? 25.94   -5.179  21.721  1   25.959 ? 1016 HOH A O   1 
HETATM 8786 O  O   . HOH G 4 .   ? -2.143  9.083   60.98   1   22.575 ? 1017 HOH A O   1 
HETATM 8787 O  O   . HOH G 4 .   ? 0.962   15.318  50.602  1   17.375 ? 1018 HOH A O   1 
HETATM 8788 O  O   . HOH G 4 .   ? 20.02   9.611   36.161  1   17.237 ? 1019 HOH A O   1 
HETATM 8789 O  O   . HOH G 4 .   ? 39.398  2.004   34.166  1   17.912 ? 1020 HOH A O   1 
HETATM 8790 O  O   . HOH G 4 .   ? 6.81    22.713  45.177  1   34.996 ? 1021 HOH A O   1 
HETATM 8791 O  O   . HOH G 4 .   ? -10.825 -7.822  32.776  1   14.228 ? 1022 HOH A O   1 
HETATM 8792 O  O   . HOH G 4 .   ? 7.73    -0.521  54.141  1   17.351 ? 1023 HOH A O   1 
HETATM 8793 O  O   . HOH G 4 .   ? -0.054  15.579  63.549  1   43.241 ? 1024 HOH A O   1 
HETATM 8794 O  O   . HOH G 4 .   ? -1.994  4.352   29.035  1   14.438 ? 1025 HOH A O   1 
HETATM 8795 O  O   . HOH G 4 .   ? -8.71   -13.478 32.304  1   25.849 ? 1026 HOH A O   1 
HETATM 8796 O  O   . HOH G 4 .   ? -0.956  -12.524 28.913  1   21.216 ? 1027 HOH A O   1 
HETATM 8797 O  O   . HOH G 4 .   ? -0.709  7.452   64.248  1   22.081 ? 1028 HOH A O   1 
HETATM 8798 O  O   . HOH G 4 .   ? 15.055  -1.796  19.022  1   17.582 ? 1029 HOH A O   1 
HETATM 8799 O  O   . HOH G 4 .   ? -5.487  9.042   53.474  1   29.441 ? 1030 HOH A O   1 
HETATM 8800 O  O   . HOH G 4 .   ? 17.024  13.486  66.953  1   30.25  ? 1031 HOH A O   1 
HETATM 8801 O  O   . HOH G 4 .   ? 34.664  -6.851  58.372  1   42.859 ? 1032 HOH A O   1 
HETATM 8802 O  O   . HOH G 4 .   ? 0.859   9.705   63.849  1   19.102 ? 1033 HOH A O   1 
HETATM 8803 O  O   . HOH G 4 .   ? 9.628   16.239  63.014  1   34.446 ? 1034 HOH A O   1 
HETATM 8804 O  O   . HOH G 4 .   ? -1.367  -11.132 62.994  1   21.77  ? 1035 HOH A O   1 
HETATM 8805 O  O   . HOH G 4 .   ? 12.689  25.569  44.248  1   36.263 ? 1036 HOH A O   1 
HETATM 8806 O  O   . HOH G 4 .   ? 25.482  -12.675 56.149  1   26.374 ? 1037 HOH A O   1 
HETATM 8807 O  O   . HOH G 4 .   ? 34.948  -6.181  28.752  1   25.91  ? 1038 HOH A O   1 
HETATM 8808 O  O   . HOH G 4 .   ? 9.297   -20     42.26   1   35.488 ? 1039 HOH A O   1 
HETATM 8809 O  O   . HOH G 4 .   ? 2.944   1.709   72.822  1   48.487 ? 1040 HOH A O   1 
HETATM 8810 O  O   . HOH G 4 .   ? -31.795 13.255  15.4    1   35.977 ? 1041 HOH A O   1 
HETATM 8811 O  O   . HOH G 4 .   ? 32.618  -3.498  68.593  1   28.986 ? 1042 HOH A O   1 
HETATM 8812 O  O   . HOH G 4 .   ? -12.643 5.524   34.098  1   18.287 ? 1043 HOH A O   1 
HETATM 8813 O  O   . HOH G 4 .   ? 26.725  8.447   48.313  1   15.691 ? 1044 HOH A O   1 
HETATM 8814 O  O   . HOH G 4 .   ? 18.095  -17.87  63.106  1   34.208 ? 1045 HOH A O   1 
HETATM 8815 O  O   . HOH G 4 .   ? 5.669   -13.886 38.875  1   34.857 ? 1046 HOH A O   1 
HETATM 8816 O  O   . HOH G 4 .   ? 18.409  3.595   35.281  1   14.19  ? 1047 HOH A O   1 
HETATM 8817 O  O   . HOH G 4 .   ? -14.931 -7.615  53.26   1   35.276 ? 1048 HOH A O   1 
HETATM 8818 O  O   . HOH G 4 .   ? 38.268  -9.791  50.711  1   33.211 ? 1049 HOH A O   1 
HETATM 8819 O  O   . HOH G 4 .   ? 5.207   6.981   22.732  1   16.692 ? 1050 HOH A O   1 
HETATM 8820 O  O   . HOH G 4 .   ? 2.915   -21.586 45.033  1   28.121 ? 1051 HOH A O   1 
HETATM 8821 O  O   . HOH G 4 .   ? 1.701   8.38    48.502  1   15.046 ? 1052 HOH A O   1 
HETATM 8822 O  O   . HOH G 4 .   ? 20.975  22.708  50.751  1   31.111 ? 1053 HOH A O   1 
HETATM 8823 O  O   . HOH G 4 .   ? -4.97   0.944   66.59   1   26.701 ? 1054 HOH A O   1 
HETATM 8824 O  O   . HOH G 4 .   ? 9.196   3.103   50.844  1   19.263 ? 1055 HOH A O   1 
HETATM 8825 O  O   . HOH G 4 .   ? 7.341   -10.007 44.767  1   14.384 ? 1056 HOH A O   1 
HETATM 8826 O  O   . HOH G 4 .   ? -9.286  7.217   28.131  1   22.59  ? 1057 HOH A O   1 
HETATM 8827 O  O   . HOH G 4 .   ? 10.237  3.866   57.861  1   14.035 ? 1058 HOH A O   1 
HETATM 8828 O  O   . HOH G 4 .   ? 35.515  5.276   42.776  1   22.599 ? 1059 HOH A O   1 
HETATM 8829 O  O   . HOH G 4 .   ? 36.115  -4.722  32.494  1   35.826 ? 1060 HOH A O   1 
HETATM 8830 O  O   . HOH G 4 .   ? 6.963   -2.767  64.965  1   16.135 ? 1061 HOH A O   1 
HETATM 8831 O  O   . HOH G 4 .   ? 1.356   -14.136 70.407  1   41.775 ? 1062 HOH A O   1 
HETATM 8832 O  O   . HOH G 4 .   ? -14.076 5.549   26.558  1   17.749 ? 1063 HOH A O   1 
HETATM 8833 O  O   . HOH G 4 .   ? 23.932  8.771   31.907  1   17.764 ? 1064 HOH A O   1 
HETATM 8834 O  O   . HOH G 4 .   ? 35.7    4.452   52.377  1   34.002 ? 1065 HOH A O   1 
HETATM 8835 O  O   . HOH G 4 .   ? 20.058  -5.014  66.569  1   28.015 ? 1066 HOH A O   1 
HETATM 8836 O  O   . HOH G 4 .   ? 22.269  10.923  39.059  1   15.281 ? 1067 HOH A O   1 
HETATM 8837 O  O   . HOH G 4 .   ? 24.572  10.604  40.588  1   14.418 ? 1068 HOH A O   1 
HETATM 8838 O  O   . HOH G 4 .   ? 31.735  11.003  38.645  1   18.049 ? 1069 HOH A O   1 
HETATM 8839 O  O   . HOH G 4 .   ? 9.81    -10.251 43.52   1   15.548 ? 1070 HOH A O   1 
HETATM 8840 O  O   . HOH G 4 .   ? 26.538  5.953   49.608  1   18.087 ? 1071 HOH A O   1 
HETATM 8841 O  O   . HOH G 4 .   ? 16.601  0.771   14.881  1   41.327 ? 1072 HOH A O   1 
HETATM 8842 O  O   . HOH G 4 .   ? 41.2    -10.772 42.655  1   30.906 ? 1073 HOH A O   1 
HETATM 8843 O  O   . HOH G 4 .   ? -22.09  15.098  23.913  1   25.47  ? 1074 HOH A O   1 
HETATM 8844 O  O   . HOH G 4 .   ? -2.651  3.695   24.726  1   26.83  ? 1075 HOH A O   1 
HETATM 8845 O  O   . HOH G 4 .   ? 36.12   -8.169  46.517  1   25.122 ? 1076 HOH A O   1 
HETATM 8846 O  O   . HOH G 4 .   ? 28.316  -1.246  23.338  1   26.857 ? 1077 HOH A O   1 
HETATM 8847 O  O   . HOH G 4 .   ? 3.361   10.379  28.592  1   20.885 ? 1078 HOH A O   1 
HETATM 8848 O  O   . HOH G 4 .   ? 0.15    6.261   49.553  1   29.29  ? 1079 HOH A O   1 
HETATM 8849 O  O   . HOH G 4 .   ? -6.405  -6.656  61.809  1   24.807 ? 1080 HOH A O   1 
HETATM 8850 O  O   . HOH G 4 .   ? 33.287  9.899   42.103  1   21.211 ? 1081 HOH A O   1 
HETATM 8851 O  O   . HOH G 4 .   ? 20.371  -12.864 64.23   1   42.994 ? 1082 HOH A O   1 
HETATM 8852 O  O   . HOH G 4 .   ? -27.967 12.562  21.511  1   25.405 ? 1083 HOH A O   1 
HETATM 8853 O  O   . HOH G 4 .   ? -16.534 -5.007  52.73   1   28.137 ? 1084 HOH A O   1 
HETATM 8854 O  O   . HOH G 4 .   ? -0.152  11.738  25.449  1   27.013 ? 1085 HOH A O   1 
HETATM 8855 O  O   . HOH G 4 .   ? 29.338  13.515  56.579  1   24.45  ? 1086 HOH A O   1 
HETATM 8856 O  O   . HOH G 4 .   ? 31.799  -6.006  36.363  1   20.977 ? 1087 HOH A O   1 
HETATM 8857 O  O   . HOH G 4 .   ? -29.982 8.436   17.484  1   26.903 ? 1088 HOH A O   1 
HETATM 8858 O  O   . HOH G 4 .   ? 27.667  -16.246 41.796  1   34.147 ? 1089 HOH A O   1 
HETATM 8859 O  O   . HOH G 4 .   ? 33.952  -1.81   44.608  1   21.954 ? 1090 HOH A O   1 
HETATM 8860 O  O   . HOH G 4 .   ? 27.304  20.411  58.227  1   25.147 ? 1091 HOH A O   1 
HETATM 8861 O  O   . HOH G 4 .   ? 16.664  -18.949 51.406  1   26.702 ? 1092 HOH A O   1 
HETATM 8862 O  O   . HOH G 4 .   ? -1.98   19.067  42.327  1   24.287 ? 1093 HOH A O   1 
HETATM 8863 O  O   . HOH G 4 .   ? 13.471  20.934  63.73   1   49.199 ? 1094 HOH A O   1 
HETATM 8864 O  O   . HOH G 4 .   ? 6.737   -7.196  44.451  1   13.367 ? 1095 HOH A O   1 
HETATM 8865 O  O   . HOH G 4 .   ? 6.037   23.015  56.869  1   34.01  ? 1096 HOH A O   1 
HETATM 8866 O  O   . HOH G 4 .   ? -18.305 -6.528  43.477  1   31.729 ? 1097 HOH A O   1 
HETATM 8867 O  O   . HOH G 4 .   ? 10.507  -5.927  70.348  1   31.104 ? 1098 HOH A O   1 
HETATM 8868 O  O   . HOH G 4 .   ? -10.994 -17.861 37.007  1   43.402 ? 1099 HOH A O   1 
HETATM 8869 O  O   . HOH G 4 .   ? 19.913  -9.826  19.919  1   46.652 ? 1100 HOH A O   1 
HETATM 8870 O  O   . HOH G 4 .   ? 25.837  -2.492  39.601  1   14.179 ? 1101 HOH A O   1 
HETATM 8871 O  O   . HOH G 4 .   ? 41.085  -12.549 45.485  1   30.186 ? 1102 HOH A O   1 
HETATM 8872 O  O   . HOH G 4 .   ? 1.359   5.465   25.05   1   20.34  ? 1103 HOH A O   1 
HETATM 8873 O  O   . HOH G 4 .   ? 27.283  -14.935 53.662  1   25.01  ? 1104 HOH A O   1 
HETATM 8874 O  O   . HOH G 4 .   ? -17.605 14.728  18.306  1   27.613 ? 1105 HOH A O   1 
HETATM 8875 O  O   . HOH G 4 .   ? 29.334  -3.917  23.745  1   26.073 ? 1106 HOH A O   1 
HETATM 8876 O  O   . HOH G 4 .   ? 28.241  19.261  50.215  1   28.497 ? 1107 HOH A O   1 
HETATM 8877 O  O   . HOH G 4 .   ? 2.594   -18.223 62.582  1   31.732 ? 1108 HOH A O   1 
HETATM 8878 O  O   . HOH G 4 .   ? 7.376   -14.999 36.927  1   37.383 ? 1109 HOH A O   1 
HETATM 8879 O  O   . HOH G 4 .   ? 17.406  -11.773 41.903  1   27.387 ? 1110 HOH A O   1 
HETATM 8880 O  O   . HOH G 4 .   ? 21.198  15.172  31.799  1   26.86  ? 1111 HOH A O   1 
HETATM 8881 O  O   . HOH G 4 .   ? -20.67  14.566  26.38   1   24.659 ? 1112 HOH A O   1 
HETATM 8882 O  O   . HOH G 4 .   ? 37.27   -5.426  49.908  1   39.896 ? 1113 HOH A O   1 
HETATM 8883 O  O   . HOH G 4 .   ? -0.614  -22.959 53.292  1   30.848 ? 1114 HOH A O   1 
HETATM 8884 O  O   . HOH G 4 .   ? -16.942 -8.354  36.527  1   26.551 ? 1115 HOH A O   1 
HETATM 8885 O  O   . HOH G 4 .   ? 13.753  9.133   42.414  1   13.351 ? 1116 HOH A O   1 
HETATM 8886 O  O   . HOH G 4 .   ? 19.134  -12.087 31.712  1   38.07  ? 1117 HOH A O   1 
HETATM 8887 O  O   . HOH G 4 .   ? 18.019  20.958  64.885  1   33.049 ? 1118 HOH A O   1 
HETATM 8888 O  O   . HOH G 4 .   ? -11.13  8.133   26.21   1   35.941 ? 1119 HOH A O   1 
HETATM 8889 O  O   . HOH G 4 .   ? 8.956   19.171  37.173  1   29.541 ? 1120 HOH A O   1 
HETATM 8890 O  O   . HOH G 4 .   ? 12.544  -5.604  31.517  1   23.74  ? 1121 HOH A O   1 
HETATM 8891 O  O   . HOH G 4 .   ? -9.189  -17.388 49.303  1   21.917 ? 1122 HOH A O   1 
HETATM 8892 O  O   . HOH G 4 .   ? 16.493  19.082  37.875  1   16.651 ? 1123 HOH A O   1 
HETATM 8893 O  O   . HOH G 4 .   ? 7.969   -5.054  71.069  1   36.102 ? 1124 HOH A O   1 
HETATM 8894 O  O   . HOH G 4 .   ? 24.367  -9.601  70.125  1   30.949 ? 1125 HOH A O   1 
HETATM 8895 O  O   . HOH G 4 .   ? 25.905  22.833  58.255  1   41.623 ? 1126 HOH A O   1 
HETATM 8896 O  O   . HOH G 4 .   ? -2.217  4.488   51.793  1   20.412 ? 1127 HOH A O   1 
HETATM 8897 O  O   . HOH G 4 .   ? -1.818  16.135  36.781  1   28.923 ? 1128 HOH A O   1 
HETATM 8898 O  O   . HOH G 4 .   ? -9.071  17.901  43.598  1   22.609 ? 1129 HOH A O   1 
HETATM 8899 O  O   . HOH G 4 .   ? -13.201 6.947   56.357  1   36.677 ? 1130 HOH A O   1 
HETATM 8900 O  O   . HOH G 4 .   ? 20.757  -17.078 44.734  1   25.597 ? 1131 HOH A O   1 
HETATM 8901 O  O   . HOH G 4 .   ? 38.824  -1.012  40.048  1   31.054 ? 1132 HOH A O   1 
HETATM 8902 O  O   . HOH G 4 .   ? 10.454  19.078  33.832  1   25.785 ? 1133 HOH A O   1 
HETATM 8903 O  O   . HOH G 4 .   ? 3.215   16.768  29.531  1   21.884 ? 1134 HOH A O   1 
HETATM 8904 O  O   . HOH G 4 .   ? -9.747  3.276   50.241  1   23.342 ? 1135 HOH A O   1 
HETATM 8905 O  O   . HOH G 4 .   ? 6.438   -16.034 27.993  1   56.03  ? 1136 HOH A O   1 
HETATM 8906 O  O   . HOH G 4 .   ? 5.337   6.504   53.286  1   15.513 ? 1137 HOH A O   1 
HETATM 8907 O  O   . HOH G 4 .   ? -21.038 1.146   40.953  1   43.744 ? 1138 HOH A O   1 
HETATM 8908 O  O   . HOH G 4 .   ? 23.206  -18.22  54.629  1   23.541 ? 1139 HOH A O   1 
HETATM 8909 O  O   . HOH G 4 .   ? 21.897  -21.915 45.278  1   29.74  ? 1140 HOH A O   1 
HETATM 8910 O  O   . HOH G 4 .   ? 16.716  -14.147 67.404  1   23.817 ? 1141 HOH A O   1 
HETATM 8911 O  O   . HOH G 4 .   ? 21.466  -1.275  20.259  1   19.972 ? 1142 HOH A O   1 
HETATM 8912 O  O   . HOH G 4 .   ? 33.191  -3.974  46.206  1   27.888 ? 1143 HOH A O   1 
HETATM 8913 O  O   . HOH G 4 .   ? 18.349  -14.368 47.853  1   17.079 ? 1144 HOH A O   1 
HETATM 8914 O  O   . HOH G 4 .   ? -2.649  11.012  27.535  1   28.943 ? 1145 HOH A O   1 
HETATM 8915 O  O   . HOH G 4 .   ? 21.817  22.164  42.756  1   20.518 ? 1146 HOH A O   1 
HETATM 8916 O  O   . HOH G 4 .   ? 25.829  -20.553 42.863  1   30.673 ? 1147 HOH A O   1 
HETATM 8917 O  O   . HOH G 4 .   ? -10.155 8.045   49.835  1   25.945 ? 1148 HOH A O   1 
HETATM 8918 O  O   . HOH G 4 .   ? 29.06   0.737   25.191  1   32.183 ? 1149 HOH A O   1 
HETATM 8919 O  O   . HOH G 4 .   ? -4.799  -22.345 38.335  1   33.585 ? 1150 HOH A O   1 
HETATM 8920 O  O   . HOH G 4 .   ? -7.619  9.308   31.882  1   24.56  ? 1151 HOH A O   1 
HETATM 8921 O  O   . HOH G 4 .   ? 22.056  -21.164 52.598  1   43.617 ? 1152 HOH A O   1 
HETATM 8922 O  O   . HOH G 4 .   ? 24.764  13.122  26.367  1   32.734 ? 1153 HOH A O   1 
HETATM 8923 O  O   . HOH G 4 .   ? 3.927   -5.072  32.345  1   19.154 ? 1154 HOH A O   1 
HETATM 8924 O  O   . HOH G 4 .   ? 5.763   6.846   68.592  1   24.441 ? 1155 HOH A O   1 
HETATM 8925 O  O   . HOH G 4 .   ? 37.718  -3.874  39.128  1   53.898 ? 1156 HOH A O   1 
HETATM 8926 O  O   . HOH G 4 .   ? 20.595  -14.838 46.121  1   18.359 ? 1157 HOH A O   1 
HETATM 8927 O  O   . HOH G 4 .   ? 35.319  -6.76   38.96   1   44.951 ? 1158 HOH A O   1 
HETATM 8928 O  O   . HOH G 4 .   ? -18.797 -3.946  50.377  1   27.303 ? 1159 HOH A O   1 
HETATM 8929 O  O   . HOH G 4 .   ? 1.348   11.346  56.121  1   30.124 ? 1160 HOH A O   1 
HETATM 8930 O  O   . HOH G 4 .   ? 8.775   20.107  59.317  1   28.726 ? 1161 HOH A O   1 
HETATM 8931 O  O   . HOH G 4 .   ? -33.507 12.31   12.464  1   29.809 ? 1162 HOH A O   1 
HETATM 8932 O  O   . HOH G 4 .   ? 37.979  4.269   41.151  1   23.218 ? 1163 HOH A O   1 
HETATM 8933 O  O   . HOH G 4 .   ? -11.435 15.069  43.902  1   22.925 ? 1164 HOH A O   1 
HETATM 8934 O  O   . HOH G 4 .   ? 2.265   8.001   24.798  1   20.208 ? 1165 HOH A O   1 
HETATM 8935 O  O   . HOH G 4 .   ? 13.451  25.617  50.233  1   51.299 ? 1166 HOH A O   1 
HETATM 8936 O  O   . HOH G 4 .   ? -10.212 4.447   54.735  1   29.663 ? 1167 HOH A O   1 
HETATM 8937 O  O   . HOH G 4 .   ? 19.251  8.134   46.027  1   13.405 ? 1168 HOH A O   1 
HETATM 8938 O  O   . HOH G 4 .   ? -11.267 -15.195 60.877  1   50.422 ? 1169 HOH A O   1 
HETATM 8939 O  O   . HOH G 4 .   ? 30.004  8.349   62.9    1   23.057 ? 1170 HOH A O   1 
HETATM 8940 O  O   . HOH G 4 .   ? 36.89   -16.248 41.003  1   31.19  ? 1171 HOH A O   1 
HETATM 8941 O  O   . HOH G 4 .   ? -1.381  14.515  47.615  1   18.528 ? 1172 HOH A O   1 
HETATM 8942 O  O   . HOH G 4 .   ? -5.951  14.171  33.706  1   26.48  ? 1173 HOH A O   1 
HETATM 8943 O  O   . HOH G 4 .   ? -7.455  4.429   51.945  1   25.489 ? 1174 HOH A O   1 
HETATM 8944 O  O   . HOH G 4 .   ? 28.718  -16.558 55.18   1   42.626 ? 1175 HOH A O   1 
HETATM 8945 O  O   . HOH G 4 .   ? 17.38   23.045  56.355  1   30.582 ? 1176 HOH A O   1 
HETATM 8946 O  O   . HOH G 4 .   ? 12.309  5.134   79.772  1   38.216 ? 1177 HOH A O   1 
HETATM 8947 O  O   . HOH G 4 .   ? 7.895   13.23   64.415  1   30.292 ? 1178 HOH A O   1 
HETATM 8948 O  O   . HOH G 4 .   ? 9.72    -21.393 58.79   1   37.031 ? 1179 HOH A O   1 
HETATM 8949 O  O   . HOH G 4 .   ? 30.187  2.302   63.261  1   20.616 ? 1180 HOH A O   1 
HETATM 8950 O  O   . HOH G 4 .   ? 1.694   -9.972  73.284  1   51.461 ? 1181 HOH A O   1 
HETATM 8951 O  O   . HOH G 4 .   ? 2.042   -4.669  30.237  1   35.821 ? 1182 HOH A O   1 
HETATM 8952 O  O   . HOH G 4 .   ? 22.197  -11.405 25.44   1   44.317 ? 1183 HOH A O   1 
HETATM 8953 O  O   . HOH G 4 .   ? -17.367 -6.032  55.047  1   33.81  ? 1184 HOH A O   1 
HETATM 8954 O  O   . HOH G 4 .   ? 8.616   -9.887  68.706  1   26.438 ? 1185 HOH A O   1 
HETATM 8955 O  O   . HOH G 4 .   ? 0.774   -16.375 65.47   1   31.987 ? 1186 HOH A O   1 
HETATM 8956 O  O   . HOH G 4 .   ? 1.332   8.022   52.91   1   22.37  ? 1187 HOH A O   1 
HETATM 8957 O  O   . HOH G 4 .   ? -2.991  -17.678 59.431  1   21.763 ? 1188 HOH A O   1 
HETATM 8958 O  O   . HOH G 4 .   ? 25.69   -18.206 43.659  1   38.13  ? 1189 HOH A O   1 
HETATM 8959 O  O   . HOH G 4 .   ? 19.494  -16.43  29.008  1   48.483 ? 1190 HOH A O   1 
HETATM 8960 O  O   . HOH G 4 .   ? 11.846  3.066   24.514  1   13.999 ? 1191 HOH A O   1 
HETATM 8961 O  O   . HOH G 4 .   ? 6.854   1.336   50.465  1   15.335 ? 1192 HOH A O   1 
HETATM 8962 O  O   . HOH G 4 .   ? 7.432   -13.293 32.507  1   25.416 ? 1193 HOH A O   1 
HETATM 8963 O  O   . HOH G 4 .   ? 16.566  22.199  59.515  1   29.92  ? 1194 HOH A O   1 
HETATM 8964 O  O   . HOH G 4 .   ? 39.981  2.709   41.794  1   35.789 ? 1195 HOH A O   1 
HETATM 8965 O  O   . HOH G 4 .   ? 9.901   -23.689 54.85   1   32.125 ? 1196 HOH A O   1 
HETATM 8966 O  O   . HOH G 4 .   ? -0.132  6.06    52.549  1   33.424 ? 1197 HOH A O   1 
HETATM 8967 O  O   . HOH G 4 .   ? 16.146  -19.29  54.445  1   35.526 ? 1198 HOH A O   1 
HETATM 8968 O  O   . HOH G 4 .   ? -48.98  -1.829  13.634  1   58.255 ? 1199 HOH A O   1 
HETATM 8969 O  O   . HOH G 4 .   ? 27.739  -3.861  21.145  1   38.573 ? 1200 HOH A O   1 
HETATM 8970 O  O   . HOH G 4 .   ? -20.436 -8.081  43.99   1   54.278 ? 1201 HOH A O   1 
HETATM 8971 O  O   . HOH G 4 .   ? 11.974  2.17    45.159  1   31.8   ? 1202 HOH A O   1 
HETATM 8972 O  O   . HOH G 4 .   ? 2.843   5.828   49.494  1   27.024 ? 1203 HOH A O   1 
HETATM 8973 O  O   . HOH G 4 .   ? 41.758  0.599   34.47   1   41.338 ? 1204 HOH A O   1 
HETATM 8974 O  O   . HOH G 4 .   ? 18.998  7.583   79.599  1   37.731 ? 1205 HOH A O   1 
HETATM 8975 O  O   . HOH G 4 .   ? 16.77   -14.855 37.015  1   30.491 ? 1206 HOH A O   1 
HETATM 8976 O  O   . HOH G 4 .   ? 36.179  -0.217  45.432  1   26.903 ? 1207 HOH A O   1 
HETATM 8977 O  O   . HOH G 4 .   ? 22.334  10.466  67.94   1   28.529 ? 1208 HOH A O   1 
HETATM 8978 O  O   . HOH G 4 .   ? 1.206   -15.373 34.754  1   24.998 ? 1209 HOH A O   1 
HETATM 8979 O  O   . HOH G 4 .   ? -13.375 2.737   38.881  1   21.339 ? 1210 HOH A O   1 
HETATM 8980 O  O   . HOH G 4 .   ? -3.252  -26.204 46.892  1   37.35  ? 1211 HOH A O   1 
HETATM 8981 O  O   . HOH G 4 .   ? -3.852  16.47   47.011  1   34.832 ? 1212 HOH A O   1 
HETATM 8982 O  O   . HOH G 4 .   ? 15.284  -22.019 17.426  1   60.789 ? 1213 HOH A O   1 
HETATM 8983 O  O   . HOH G 4 .   ? -4.187  -23.854 45.301  1   35.93  ? 1214 HOH A O   1 
HETATM 8984 O  O   . HOH G 4 .   ? -10.25  5.743   51.01   1   33.397 ? 1215 HOH A O   1 
HETATM 8985 O  O   . HOH G 4 .   ? 28.286  0.111   20.029  1   23.834 ? 1216 HOH A O   1 
HETATM 8986 O  O   . HOH G 4 .   ? 8.537   -0.967  72.561  1   41.032 ? 1217 HOH A O   1 
HETATM 8987 O  O   . HOH G 4 .   ? 34.219  -17.303 40.704  1   36.304 ? 1218 HOH A O   1 
HETATM 8988 O  O   . HOH G 4 .   ? 13.055  -21.082 56.188  1   28.948 ? 1219 HOH A O   1 
HETATM 8989 O  O   . HOH G 4 .   ? 10.982  21.002  35.728  1   36.377 ? 1220 HOH A O   1 
HETATM 8990 O  O   . HOH G 4 .   ? 2.521   -28.023 53.239  1   50.6   ? 1221 HOH A O   1 
HETATM 8991 O  O   . HOH G 4 .   ? 30.881  9.462   65.195  1   42.724 ? 1222 HOH A O   1 
HETATM 8992 O  O   . HOH G 4 .   ? 3.894   23.033  38.796  1   43.826 ? 1223 HOH A O   1 
HETATM 8993 O  O   . HOH G 4 .   ? 32.012  -6.993  58.539  1   41.004 ? 1224 HOH A O   1 
HETATM 8994 O  O   . HOH G 4 .   ? -27.122 13.234  14.226  1   40.823 ? 1225 HOH A O   1 
HETATM 8995 O  O   . HOH G 4 .   ? 42.229  4.048   36.47   1   42.046 ? 1226 HOH A O   1 
HETATM 8996 O  O   . HOH G 4 .   ? 2.284   -26.952 41.977  1   50.992 ? 1227 HOH A O   1 
HETATM 8997 O  O   . HOH G 4 .   ? -25.401 15.501  31.504  1   59.597 ? 1228 HOH A O   1 
HETATM 8998 O  O   . HOH G 4 .   ? -21.931 15.333  28.7    1   39.468 ? 1229 HOH A O   1 
HETATM 8999 O  O   . HOH G 4 .   ? 14.249  20.088  36.592  1   33.437 ? 1230 HOH A O   1 
HETATM 9000 O  O   . HOH G 4 .   ? -3.391  -23.113 53.104  1   33.18  ? 1231 HOH A O   1 
HETATM 9001 O  O   . HOH G 4 .   ? 25.974  19.897  38.464  1   31.308 ? 1232 HOH A O   1 
HETATM 9002 O  O   . HOH G 4 .   ? 0.355   10.613  52.725  1   38.154 ? 1233 HOH A O   1 
HETATM 9003 O  O   . HOH G 4 .   ? -5.331  -16.54  60.335  1   30.426 ? 1234 HOH A O   1 
HETATM 9004 O  O   . HOH G 4 .   ? 30.46   -10.933 30.698  1   42.049 ? 1235 HOH A O   1 
HETATM 9005 O  O   . HOH G 4 .   ? -2.66   7.355   26.202  1   37.276 ? 1236 HOH A O   1 
HETATM 9006 O  O   . HOH G 4 .   ? 8.92    -0.387  50.5    1   14.395 ? 1237 HOH A O   1 
HETATM 9007 O  O   . HOH G 4 .   ? 14.378  -5.478  13.31   1   43.426 ? 1238 HOH A O   1 
HETATM 9008 O  O   . HOH G 4 .   ? 22.847  -4.203  29.064  1   22.762 ? 1239 HOH A O   1 
HETATM 9009 O  O   . HOH G 4 .   ? -28.038 8.688   25.477  1   36.564 ? 1240 HOH A O   1 
HETATM 9010 O  O   . HOH G 4 .   ? 19.701  13.769  68.199  1   40.048 ? 1241 HOH A O   1 
HETATM 9011 O  O   . HOH G 4 .   ? 23.37   22.62   56.787  1   28.019 ? 1242 HOH A O   1 
HETATM 9012 O  O   . HOH G 4 .   ? 2.412   22.598  54.498  1   36.569 ? 1243 HOH A O   1 
HETATM 9013 O  O   . HOH G 4 .   ? 15.172  -3.612  15.355  1   37.64  ? 1244 HOH A O   1 
HETATM 9014 O  O   . HOH G 4 .   ? 29.6    16.908  53.38   1   34.699 ? 1245 HOH A O   1 
HETATM 9015 O  O   . HOH G 4 .   ? 35.907  -14.869 50.585  1   40.786 ? 1246 HOH A O   1 
HETATM 9016 O  O   . HOH G 4 .   ? 38.695  6.59    37.116  1   33.245 ? 1247 HOH A O   1 
HETATM 9017 O  O   . HOH G 4 .   ? 39.124  -1.518  37.355  1   42.578 ? 1248 HOH A O   1 
HETATM 9018 O  O   . HOH G 4 .   ? -1.521  3.015   68.68   1   41.082 ? 1249 HOH A O   1 
HETATM 9019 O  O   . HOH G 4 .   ? -27.406 15.213  22.29   1   54.163 ? 1250 HOH A O   1 
HETATM 9020 O  O   . HOH G 4 .   ? -1.026  5.276   26.562  1   21.22  ? 1251 HOH A O   1 
HETATM 9021 O  O   . HOH G 4 .   ? 23.487  -17.033 44.416  1   24.095 ? 1252 HOH A O   1 
HETATM 9022 O  O   . HOH G 4 .   ? 16.085  9.482   17.148  1   27.531 ? 1253 HOH A O   1 
HETATM 9023 O  O   . HOH G 4 .   ? -14.145 -20.473 51.772  1   46.131 ? 1254 HOH A O   1 
HETATM 9024 O  O   . HOH G 4 .   ? 33.125  -4.294  65.144  1   33.048 ? 1255 HOH A O   1 
HETATM 9025 O  O   . HOH G 4 .   ? 31.577  20.965  49.003  1   48.995 ? 1256 HOH A O   1 
HETATM 9026 O  O   . HOH G 4 .   ? 15.744  11.495  20.606  1   27.436 ? 1257 HOH A O   1 
HETATM 9027 O  O   . HOH G 4 .   ? 4.276   19.837  35.621  1   37.481 ? 1258 HOH A O   1 
HETATM 9028 O  O   . HOH G 4 .   ? -18.347 -13.147 46.849  1   32.469 ? 1259 HOH A O   1 
HETATM 9029 O  O   . HOH G 4 .   ? 18.53   -16.395 38.365  1   37.543 ? 1260 HOH A O   1 
HETATM 9030 O  O   . HOH G 4 .   ? -8.034  12.943  32.694  1   32.5   ? 1261 HOH A O   1 
HETATM 9031 O  O   . HOH G 4 .   ? -4.973  9.365   27.563  1   48.549 ? 1262 HOH A O   1 
HETATM 9032 O  O   . HOH G 4 .   ? -9.44   -19.697 51.201  1   52.602 ? 1263 HOH A O   1 
HETATM 9033 O  O   . HOH G 4 .   ? 25.201  -18.329 52.693  1   28.495 ? 1264 HOH A O   1 
HETATM 9034 O  O   . HOH G 4 .   ? -3.859  -13.969 65.191  1   45.245 ? 1265 HOH A O   1 
HETATM 9035 O  O   . HOH G 4 .   ? -15.554 -10.627 54.514  1   48.051 ? 1266 HOH A O   1 
HETATM 9036 O  O   . HOH G 4 .   ? 16.223  -4.956  73.487  1   32.987 ? 1267 HOH A O   1 
HETATM 9037 O  O   . HOH G 4 .   ? -29.538 10.141  7.725   1   26.932 ? 1268 HOH A O   1 
HETATM 9038 O  O   . HOH G 4 .   ? -4.979  5.995   62.892  1   33.999 ? 1269 HOH A O   1 
HETATM 9039 O  O   . HOH G 4 .   ? -20.686 16.65   22.054  1   39.131 ? 1270 HOH A O   1 
HETATM 9040 O  O   . HOH G 4 .   ? -4.754  18.617  35.447  1   34.3   ? 1271 HOH A O   1 
HETATM 9041 O  O   . HOH G 4 .   ? 4.97    15.552  25.386  1   46.232 ? 1272 HOH A O   1 
HETATM 9042 O  O   . HOH G 4 .   ? 22.164  -8.498  20.498  1   44.013 ? 1273 HOH A O   1 
HETATM 9043 O  O   . HOH G 4 .   ? -12.367 9.207   50.93   1   44.203 ? 1274 HOH A O   1 
HETATM 9044 O  O   . HOH G 4 .   ? -5.318  15.313  31.57   1   36.013 ? 1275 HOH A O   1 
HETATM 9045 O  O   . HOH G 4 .   ? -36.261 12.207  13.06   1   33.256 ? 1276 HOH A O   1 
HETATM 9046 O  O   . HOH G 4 .   ? 27.12   -18.941 54.531  1   39.197 ? 1277 HOH A O   1 
HETATM 9047 O  O   . HOH G 4 .   ? 19.227  -13.516 40.856  1   33.427 ? 1278 HOH A O   1 
HETATM 9048 O  O   . HOH G 4 .   ? -18.315 -6.109  36.333  1   35.79  ? 1279 HOH A O   1 
HETATM 9049 O  O   . HOH G 4 .   ? -30.492 12.601  8.62    1   46.773 ? 1280 HOH A O   1 
HETATM 9050 O  O   . HOH G 4 .   ? -37.5   10.043  13.261  1   33.826 ? 1281 HOH A O   1 
HETATM 9051 O  O   . HOH G 4 .   ? 24.665  -7.395  19.89   1   33.793 ? 1282 HOH A O   1 
HETATM 9052 O  O   . HOH G 4 .   ? 29.037  19.697  54.146  1   33.875 ? 1283 HOH A O   1 
HETATM 9053 O  O   . HOH G 4 .   ? 3.242   -33.862 21.186  1   58.173 ? 1284 HOH A O   1 
HETATM 9054 O  O   . HOH G 4 .   ? 37.958  -6.695  47.736  1   38.02  ? 1285 HOH A O   1 
HETATM 9055 O  O   . HOH G 4 .   ? -3.054  -20.019 58.093  1   38.637 ? 1286 HOH A O   1 
HETATM 9056 O  O   . HOH G 4 .   ? -1.085  13.55   50.149  1   19.68  ? 1287 HOH A O   1 
HETATM 9057 O  O   . HOH G 4 .   ? 40.577  -17.536 46.098  1   49.125 ? 1288 HOH A O   1 
HETATM 9058 O  O   . HOH G 4 .   ? 2.688   20.044  33.119  1   37.937 ? 1289 HOH A O   1 
HETATM 9059 O  O   . HOH G 4 .   ? 32.702  -0.588  60.379  1   36.162 ? 1290 HOH A O   1 
HETATM 9060 O  O   . HOH G 4 .   ? 13.055  -5.644  71.026  1   28.637 ? 1291 HOH A O   1 
HETATM 9061 O  O   . HOH G 4 .   ? 15.551  -18.367 64.585  1   54.914 ? 1292 HOH A O   1 
HETATM 9062 O  O   . HOH G 4 .   ? -1.755  7.252   55.096  1   26.366 ? 1293 HOH A O   1 
HETATM 9063 O  O   . HOH G 4 .   ? 23.645  -18.012 57.151  1   30.152 ? 1294 HOH A O   1 
HETATM 9064 O  O   . HOH G 4 .   ? 25.634  17.117  26.194  1   57.655 ? 1295 HOH A O   1 
HETATM 9065 O  O   . HOH G 4 .   ? 32.208  6.745   62.515  1   30.127 ? 1296 HOH A O   1 
HETATM 9066 O  O   . HOH G 4 .   ? -9.983  -8.787  62.745  1   31.69  ? 1297 HOH A O   1 
HETATM 9067 O  O   . HOH G 4 .   ? -24.471 16.458  24.939  1   49.406 ? 1298 HOH A O   1 
HETATM 9068 O  O   . HOH G 4 .   ? -0.471  -20.403 54.284  1   29.261 ? 1299 HOH A O   1 
HETATM 9069 O  O   . HOH G 4 .   ? 33.946  11.268  44.383  1   26.803 ? 1300 HOH A O   1 
HETATM 9070 O  O   . HOH G 4 .   ? -31.53  9.893   18.851  1   44.363 ? 1301 HOH A O   1 
HETATM 9071 O  O   . HOH G 4 .   ? 10.291  26.978  55.677  1   45.938 ? 1302 HOH A O   1 
HETATM 9072 O  O   . HOH G 4 .   ? 29.873  21.057  58.785  1   39.834 ? 1303 HOH A O   1 
HETATM 9073 O  O   . HOH G 4 .   ? -2.303  -16.18  65.462  1   43.846 ? 1304 HOH A O   1 
HETATM 9074 O  O   . HOH G 4 .   ? 21.287  10.565  20.978  1   49.6   ? 1305 HOH A O   1 
HETATM 9075 O  O   . HOH G 4 .   ? 6.351   4.114   52.481  1   16.584 ? 1306 HOH A O   1 
HETATM 9076 O  O   . HOH G 4 .   ? 34.11   11.717  40.092  1   22.537 ? 1307 HOH A O   1 
HETATM 9077 O  O   . HOH G 4 .   ? 40.004  4.326   35.25   1   35.071 ? 1308 HOH A O   1 
HETATM 9078 O  O   . HOH G 4 .   ? 35.306  8.038   42.656  1   25.198 ? 1309 HOH A O   1 
HETATM 9079 O  O   . HOH G 4 .   ? -2.401  -2.449  67.927  1   33.335 ? 1310 HOH A O   1 
HETATM 9080 O  O   . HOH G 4 .   ? -17.79  14.51   25.983  1   41.73  ? 1311 HOH A O   1 
HETATM 9081 O  O   . HOH G 4 .   ? 28.576  -15.012 39.309  1   50.462 ? 1312 HOH A O   1 
HETATM 9082 O  O   . HOH G 4 .   ? -17.81  -3.121  58.395  1   46.083 ? 1313 HOH A O   1 
HETATM 9083 O  O   . HOH G 4 .   ? 7.359   6.675   73.951  1   44.19  ? 1314 HOH A O   1 
HETATM 9084 O  O   . HOH G 4 .   ? -3.439  13.448  28.031  1   30.654 ? 1315 HOH A O   1 
HETATM 9085 O  O   . HOH G 4 .   ? 6.666   1.681   53.406  1   22.637 ? 1316 HOH A O   1 
HETATM 9086 O  O   . HOH G 4 .   ? 1.397   21.054  56.864  1   42.118 ? 1317 HOH A O   1 
HETATM 9087 O  O   . HOH G 4 .   ? 31.531  18.805  50.547  1   36.123 ? 1318 HOH A O   1 
HETATM 9088 O  O   . HOH G 4 .   ? -4.653  5.152   52.822  1   29.004 ? 1319 HOH A O   1 
HETATM 9089 O  O   . HOH G 4 .   ? 7.531   -20.24  40.201  1   40.218 ? 1320 HOH A O   1 
HETATM 9090 O  O   . HOH G 4 .   ? -14.275 -14.239 58.724  1   48.328 ? 1321 HOH A O   1 
HETATM 9091 O  O   . HOH G 4 .   ? 9.804   22.633  59.269  1   39.528 ? 1322 HOH A O   1 
HETATM 9092 O  O   . HOH G 4 .   ? 30.517  2.665   60.585  1   29.765 ? 1323 HOH A O   1 
HETATM 9093 O  O   . HOH G 4 .   ? 30.884  -7.717  38.289  1   20.89  ? 1324 HOH A O   1 
HETATM 9094 O  O   . HOH G 4 .   ? 0.692   -24.539 55.087  1   41.969 ? 1325 HOH A O   1 
HETATM 9095 O  O   . HOH G 4 .   ? 24.956  23.457  64.248  1   52.711 ? 1326 HOH A O   1 
HETATM 9096 O  O   . HOH G 4 .   ? 19.256  -6.223  71.452  1   28.148 ? 1327 HOH A O   1 
HETATM 9097 O  O   . HOH G 4 .   ? 32.006  15.831  43.089  1   36.319 ? 1328 HOH A O   1 
HETATM 9098 O  O   . HOH G 4 .   ? -4.837  -22.27  47.167  1   28.948 ? 1329 HOH A O   1 
HETATM 9099 O  O   . HOH G 4 .   ? 29.843  -9.795  36.663  1   32.939 ? 1330 HOH A O   1 
HETATM 9100 O  O   . HOH G 4 .   ? -12.778 5.974   39.014  1   22.575 ? 1331 HOH A O   1 
HETATM 9101 O  O   . HOH G 4 .   ? 7.309   -21.082 44.29   1   33.308 ? 1332 HOH A O   1 
HETATM 9102 O  O   . HOH G 4 .   ? -20.332 -0.422  52.342  1   42.721 ? 1333 HOH A O   1 
HETATM 9103 O  O   . HOH G 4 .   ? -17.281 -10.58  50.483  1   31.368 ? 1334 HOH A O   1 
HETATM 9104 O  O   . HOH G 4 .   ? -4.439  13.926  53.775  1   34.835 ? 1335 HOH A O   1 
HETATM 9105 O  O   . HOH G 4 .   ? -37.147 8.281   7.877   1   57.931 ? 1336 HOH A O   1 
HETATM 9106 O  O   . HOH G 4 .   ? 24.69   -0.745  70.396  1   24.328 ? 1337 HOH A O   1 
HETATM 9107 O  O   . HOH G 4 .   ? -3.471  18.697  39.924  1   23.477 ? 1338 HOH A O   1 
HETATM 9108 O  O   . HOH G 4 .   ? -4.734  8.467   61.285  1   37.783 ? 1339 HOH A O   1 
HETATM 9109 O  O   . HOH G 4 .   ? -13.137 -12.633 54.664  1   27.011 ? 1340 HOH A O   1 
HETATM 9110 O  O   . HOH G 4 .   ? -5.782  3.667   66.402  1   33.352 ? 1341 HOH A O   1 
HETATM 9111 O  O   . HOH G 4 .   ? 10.323  -2.286  71.126  1   33.42  ? 1342 HOH A O   1 
HETATM 9112 O  O   . HOH G 4 .   ? -1.225  8.406   50.134  1   27.886 ? 1343 HOH A O   1 
HETATM 9113 O  O   . HOH G 4 .   ? -3.264  16.169  39.115  1   18.05  ? 1344 HOH A O   1 
HETATM 9114 O  O   . HOH G 4 .   ? -3.503  7.302   64.59   1   32.211 ? 1345 HOH A O   1 
HETATM 9115 O  O   . HOH G 4 .   ? -3.724  5.374   55.083  1   24.122 ? 1346 HOH A O   1 
HETATM 9116 O  O   . HOH G 4 .   ? -1.933  9.714   58.403  1   40.688 ? 1347 HOH A O   1 
HETATM 9117 O  O   . HOH G 4 .   ? -29.763 12.221  19.296  1   40.16  ? 1348 HOH A O   1 
HETATM 9118 O  O   . HOH G 4 .   ? 17.085  -1.715  11.42   1   61.887 ? 1349 HOH A O   1 
HETATM 9119 O  O   . HOH G 4 .   ? 37.781  -3.394  36.442  1   34.613 ? 1350 HOH A O   1 
HETATM 9120 O  O   . HOH G 4 .   ? 4.295   17.34   26.965  1   27.248 ? 1351 HOH A O   1 
HETATM 9121 O  O   . HOH G 4 .   ? -22.41  -12.456 44.898  1   60.019 ? 1352 HOH A O   1 
HETATM 9122 O  O   . HOH G 4 .   ? 5.442   20.469  29.263  1   31.503 ? 1353 HOH A O   1 
HETATM 9123 O  O   . HOH G 4 .   ? 34.465  -10.298 30.673  1   48.564 ? 1354 HOH A O   1 
HETATM 9124 O  O   . HOH G 4 .   ? -8.556  -4.78   64.779  1   43.607 ? 1355 HOH A O   1 
HETATM 9125 O  O   . HOH G 4 .   ? 20.05   -16.857 42.077  1   34.978 ? 1356 HOH A O   1 
HETATM 9126 O  O   . HOH G 4 .   ? 31.315  -7.208  33.817  1   28.088 ? 1357 HOH A O   1 
HETATM 9127 O  O   . HOH G 4 .   ? -0.553  15.716  54.37   1   32.601 ? 1358 HOH A O   1 
HETATM 9128 O  O   . HOH G 4 .   ? 19.245  8.837   19.35   1   35.435 ? 1359 HOH A O   1 
HETATM 9129 O  O   . HOH G 4 .   ? -1.904  18.155  52.952  1   40.673 ? 1360 HOH A O   1 
HETATM 9130 O  O   . HOH G 4 .   ? -12.248 -7.328  63.872  1   45.071 ? 1361 HOH A O   1 
HETATM 9131 O  O   . HOH G 4 .   ? -11.807 7.897   54.061  1   51.929 ? 1362 HOH A O   1 
HETATM 9132 O  O   . HOH G 4 .   ? 34.617  -1.619  57.492  1   45.28  ? 1363 HOH A O   1 
HETATM 9133 O  O   . HOH G 4 .   ? -17.964 -6.3    50.93   1   36.573 ? 1364 HOH A O   1 
HETATM 9134 O  O   . HOH G 4 .   ? 20.101  -12.094 36.54   1   32.393 ? 1365 HOH A O   1 
HETATM 9135 O  O   . HOH G 4 .   ? 19.367  23.369  42.286  1   21.317 ? 1366 HOH A O   1 
HETATM 9136 O  O   . HOH G 4 .   ? 35.158  -13.112 52.066  1   35.546 ? 1367 HOH A O   1 
HETATM 9137 O  O   . HOH G 4 .   ? -16.304 0.106   59.017  1   42.171 ? 1368 HOH A O   1 
HETATM 9138 O  O   . HOH G 4 .   ? 1.445   -20.835 56.439  1   35.376 ? 1369 HOH A O   1 
HETATM 9139 O  O   . HOH G 4 .   ? 35.28   -17.861 52.195  1   40.381 ? 1370 HOH A O   1 
HETATM 9140 O  O   . HOH G 4 .   ? -28.93  9.125   30.338  1   39.901 ? 1371 HOH A O   1 
HETATM 9141 O  O   . HOH G 4 .   ? -0.661  18.665  36.559  1   29.379 ? 1372 HOH A O   1 
HETATM 9142 O  O   . HOH G 4 .   ? -6.83   0.045   68.36   1   47.598 ? 1373 HOH A O   1 
HETATM 9143 O  O   . HOH G 4 .   ? 3.72    0.702   75.138  1   48.23  ? 1374 HOH A O   1 
HETATM 9144 O  O   . HOH G 4 .   ? -8.611  -19.485 60.408  1   63.682 ? 1375 HOH A O   1 
HETATM 9145 O  O   . HOH G 4 .   ? -8.166  5.901   53.761  1   29.651 ? 1376 HOH A O   1 
HETATM 9146 O  O   . HOH G 4 .   ? 41.382  -8.317  44.069  1   55.179 ? 1377 HOH A O   1 
HETATM 9147 O  O   . HOH G 4 .   ? 0.007   6.67    66.757  1   25.173 ? 1378 HOH A O   1 
HETATM 9148 O  O   . HOH G 4 .   ? 31.23   -14.152 39.759  1   39.067 ? 1379 HOH A O   1 
HETATM 9149 O  O   . HOH G 4 .   ? 34.517  -5.903  36.513  1   28.041 ? 1380 HOH A O   1 
HETATM 9150 O  O   . HOH G 4 .   ? 16.966  -16.357 33.004  1   35.784 ? 1381 HOH A O   1 
HETATM 9151 O  O   . HOH G 4 .   ? 43.546  2.120   32.967  1   43.458 ? 1382 HOH A O   1 
HETATM 9152 O  O   . HOH G 4 .   ? 1.327   -27.125 55.227  1   50.37  ? 1383 HOH A O   1 
HETATM 9153 O  O   . HOH G 4 .   ? 0.554   17.463  29.596  1   24.683 ? 1384 HOH A O   1 
HETATM 9154 O  O   . HOH G 4 .   ? 18.946  -14.428 32.836  1   31.072 ? 1385 HOH A O   1 
HETATM 9155 O  O   . HOH G 4 .   ? -0.594  19.018  33.852  1   40.818 ? 1386 HOH A O   1 
HETATM 9156 O  O   . HOH G 4 .   ? 1.199   10.603  66.365  1   29.654 ? 1387 HOH A O   1 
HETATM 9157 O  O   . HOH G 4 .   ? -2.923  8.96    52.917  1   30.883 ? 1388 HOH A O   1 
HETATM 9158 O  O   . HOH G 4 .   ? -51.870 7.702   17.232  1   37.347 ? 1389 HOH A O   1 
HETATM 9159 O  O   . HOH G 4 .   ? -46.022 -6.035  10.198  1   48.449 ? 1390 HOH A O   1 
HETATM 9160 O  O   . HOH G 4 .   ? -16.656 -12.026 52.665  1   58.187 ? 1391 HOH A O   1 
HETATM 9161 O  O   . HOH G 4 .   ? 20.165  -14.403 35.336  1   46.971 ? 1392 HOH A O   1 
HETATM 9162 O  O   . HOH G 4 .   ? -2.816  20.095  37.747  1   38.934 ? 1393 HOH A O   1 
HETATM 9163 O  O   . HOH G 4 .   ? -9.052  0.757   69.25   1   60.584 ? 1394 HOH A O   1 
HETATM 9164 O  O   . HOH G 4 .   ? -8.426  -3.745  67.37   1   49.978 ? 1395 HOH A O   1 
HETATM 9165 O  O   . HOH G 4 .   ? -2.489  14.3    52.289  1   34.771 ? 1396 HOH A O   1 
HETATM 9166 O  O   . HOH G 4 .   ? -2.361  5.674   67.948  1   43.832 ? 1397 HOH A O   1 
HETATM 9167 O  O   . HOH G 4 .   ? -12.16  -7.654  66.472  1   53.615 ? 1398 HOH A O   1 
HETATM 9168 O  O   . HOH H 4 .   ? -4.584  -30.609 42.032  1   36.801 ? 701  HOH B O   1 
HETATM 9169 O  O   . HOH H 4 .   ? 7.698   6.255   4.97    1   49.349 ? 702  HOH B O   1 
HETATM 9170 O  O   . HOH H 4 .   ? 0.511   -10.13  28.566  1   30.244 ? 703  HOH B O   1 
HETATM 9171 O  O   . HOH H 4 .   ? -30.157 -30.487 9.297   1   37.529 ? 704  HOH B O   1 
HETATM 9172 O  O   . HOH H 4 .   ? -16.75  -17.379 39.175  1   33.707 ? 705  HOH B O   1 
HETATM 9173 O  O   . HOH H 4 .   ? -32     -13.442 -16.648 1   37.446 ? 706  HOH B O   1 
HETATM 9174 O  O   . HOH H 4 .   ? -41.273 -1.04   3.699   1   32.753 ? 707  HOH B O   1 
HETATM 9175 O  O   . HOH H 4 .   ? -2.214  11.468  16.968  1   32.498 ? 708  HOH B O   1 
HETATM 9176 O  O   . HOH H 4 .   ? 12.284  -10.422 13.849  1   46.29  ? 709  HOH B O   1 
HETATM 9177 O  O   . HOH H 4 .   ? 2.336   12.668  5.763   1   39.543 ? 710  HOH B O   1 
HETATM 9178 O  O   . HOH H 4 .   ? -25.942 2.983   35.188  1   36.46  ? 711  HOH B O   1 
HETATM 9179 O  O   . HOH H 4 .   ? 9.704   -22.149 2.585   1   43.917 ? 712  HOH B O   1 
HETATM 9180 O  O   . HOH H 4 .   ? -23.688 11.314  7.627   1   35.567 ? 713  HOH B O   1 
HETATM 9181 O  O   . HOH H 4 .   ? -0.056  -23.339 20.745  1   34.274 ? 714  HOH B O   1 
HETATM 9182 O  O   . HOH H 4 .   ? -16.791 10.362  22.021  1   27.974 ? 715  HOH B O   1 
HETATM 9183 O  O   . HOH H 4 .   ? 14.208  16.768  15.133  1   44.344 ? 716  HOH B O   1 
HETATM 9184 O  O   . HOH H 4 .   ? 2.49    -25.472 11.386  1   41.475 ? 717  HOH B O   1 
HETATM 9185 O  O   . HOH H 4 .   ? -12.899 11.737  7.648   1   33.065 ? 718  HOH B O   1 
HETATM 9186 O  O   . HOH H 4 .   ? -32.872 -8.256  -16.078 1   31.984 ? 719  HOH B O   1 
HETATM 9187 O  O   . HOH H 4 .   ? -29.076 -27.996 10.687  1   27.962 ? 720  HOH B O   1 
HETATM 9188 O  O   . HOH H 4 .   ? 8.932   3.672   4.698   1   40.784 ? 721  HOH B O   1 
HETATM 9189 O  O   . HOH H 4 .   ? -8.682  12.324  12.878  1   32.239 ? 722  HOH B O   1 
HETATM 9190 O  O   . HOH H 4 .   ? -43.268 -5.657  22.086  1   33.457 ? 723  HOH B O   1 
HETATM 9191 O  O   . HOH H 4 .   ? -32.27  -12.016 17.571  1   17.089 ? 724  HOH B O   1 
HETATM 9192 O  O   . HOH H 4 .   ? 12.592  -6.842  7.559   1   46.211 ? 725  HOH B O   1 
HETATM 9193 O  O   . HOH H 4 .   ? -38.427 -21.38  11.352  1   26.88  ? 726  HOH B O   1 
HETATM 9194 O  O   . HOH H 4 .   ? 9.794   -14.771 1.735   1   37.898 ? 727  HOH B O   1 
HETATM 9195 O  O   . HOH H 4 .   ? 11.148  -12.826 5.635   1   32.399 ? 728  HOH B O   1 
HETATM 9196 O  O   . HOH H 4 .   ? -38.935 -2.789  27.499  1   29.968 ? 729  HOH B O   1 
HETATM 9197 O  O   . HOH H 4 .   ? 10.583  -6.765  14.983  1   35.342 ? 730  HOH B O   1 
HETATM 9198 O  O   . HOH H 4 .   ? -9.999  -25.858 -11.55  1   37.996 ? 731  HOH B O   1 
HETATM 9199 O  O   . HOH H 4 .   ? 1.973   5.432   1.258   1   31.27  ? 732  HOH B O   1 
HETATM 9200 O  O   . HOH H 4 .   ? -17.189 5.35    -10.827 1   27.25  ? 733  HOH B O   1 
HETATM 9201 O  O   . HOH H 4 .   ? -15.582 13.667  14.487  1   26.14  ? 734  HOH B O   1 
HETATM 9202 O  O   . HOH H 4 .   ? -0.564  8.733   15.063  1   36.196 ? 735  HOH B O   1 
HETATM 9203 O  O   . HOH H 4 .   ? 10.367  -15.464 -1.087  1   48.7   ? 736  HOH B O   1 
HETATM 9204 O  O   . HOH H 4 .   ? -17.077 -14.286 -24.369 1   56.559 ? 737  HOH B O   1 
HETATM 9205 O  O   . HOH H 4 .   ? -4.098  -18.791 -10.682 1   25.951 ? 738  HOH B O   1 
HETATM 9206 O  O   . HOH H 4 .   ? -13.371 -19.055 47.634  1   42.58  ? 739  HOH B O   1 
HETATM 9207 O  O   . HOH H 4 .   ? -11.506 -16.183 21.847  1   30.476 ? 740  HOH B O   1 
HETATM 9208 O  O   . HOH H 4 .   ? 1.625   -25.895 19.768  1   34.907 ? 741  HOH B O   1 
HETATM 9209 O  O   . HOH H 4 .   ? -32.357 -19.05  1.682   1   37.835 ? 742  HOH B O   1 
HETATM 9210 O  O   . HOH H 4 .   ? -14.14  -11.126 -8.604  1   22.064 ? 743  HOH B O   1 
HETATM 9211 O  O   . HOH H 4 .   ? -15.841 -11.981 36.276  1   23.703 ? 744  HOH B O   1 
HETATM 9212 O  O   . HOH H 4 .   ? 8.37    -5.063  15.333  1   16.88  ? 745  HOH B O   1 
HETATM 9213 O  O   . HOH H 4 .   ? -9.176  -23.209 39.546  1   25.185 ? 746  HOH B O   1 
HETATM 9214 O  O   . HOH H 4 .   ? 2.828   4.645   9.257   1   24.504 ? 747  HOH B O   1 
HETATM 9215 O  O   . HOH H 4 .   ? -0.317  -24.581 -8.45   1   37.82  ? 748  HOH B O   1 
HETATM 9216 O  O   . HOH H 4 .   ? 5.857   -3.259  -0.984  1   43.776 ? 749  HOH B O   1 
HETATM 9217 O  O   . HOH H 4 .   ? -13.885 -16.271 15.141  1   20.127 ? 750  HOH B O   1 
HETATM 9218 O  O   . HOH H 4 .   ? -39.865 -18.762 7.81    1   41.152 ? 751  HOH B O   1 
HETATM 9219 O  O   . HOH H 4 .   ? 0.726   -20.847 12.977  1   22.819 ? 752  HOH B O   1 
HETATM 9220 O  O   . HOH H 4 .   ? -19.044 -4.571  -18.371 1   47.676 ? 753  HOH B O   1 
HETATM 9221 O  O   . HOH H 4 .   ? -33.396 -20.349 -10.136 1   26.192 ? 754  HOH B O   1 
HETATM 9222 O  O   . HOH H 4 .   ? -4.373  -14.509 -13.05  1   29.417 ? 755  HOH B O   1 
HETATM 9223 O  O   . HOH H 4 .   ? 6.524   -18.994 3.285   1   24.161 ? 756  HOH B O   1 
HETATM 9224 O  O   . HOH H 4 .   ? -28.813 -3.804  32.62   1   34.477 ? 757  HOH B O   1 
HETATM 9225 O  O   . HOH H 4 .   ? -41.265 -8.659  6.212   1   38.721 ? 758  HOH B O   1 
HETATM 9226 O  O   . HOH H 4 .   ? -30.492 -28.628 -8.709  1   35.512 ? 759  HOH B O   1 
HETATM 9227 O  O   . HOH H 4 .   ? -4.695  -27.403 15.615  1   39.84  ? 760  HOH B O   1 
HETATM 9228 O  O   . HOH H 4 .   ? -42.116 -13.431 -2.461  1   42.322 ? 761  HOH B O   1 
HETATM 9229 O  O   . HOH H 4 .   ? -21.98  10.334  -0.575  1   37.185 ? 762  HOH B O   1 
HETATM 9230 O  O   . HOH H 4 .   ? -23.35  -0.662  11.353  1   15.395 ? 763  HOH B O   1 
HETATM 9231 O  O   . HOH H 4 .   ? -30.606 -23.219 19.551  1   34.721 ? 764  HOH B O   1 
HETATM 9232 O  O   . HOH H 4 .   ? -28.424 -29.241 12.906  1   29.805 ? 765  HOH B O   1 
HETATM 9233 O  O   . HOH H 4 .   ? -20.832 -2.496  26.156  1   15.735 ? 766  HOH B O   1 
HETATM 9234 O  O   . HOH H 4 .   ? -34.298 4.2     -11.196 1   34.512 ? 767  HOH B O   1 
HETATM 9235 O  O   . HOH H 4 .   ? -31.236 -24.881 -14     1   34.387 ? 768  HOH B O   1 
HETATM 9236 O  O   . HOH H 4 .   ? -20.987 -19.445 20.344  1   35.131 ? 769  HOH B O   1 
HETATM 9237 O  O   . HOH H 4 .   ? -27.388 2.404   -16.133 1   35.869 ? 770  HOH B O   1 
HETATM 9238 O  O   . HOH H 4 .   ? -18.216 -28.098 10.435  1   33.504 ? 771  HOH B O   1 
HETATM 9239 O  O   . HOH H 4 .   ? 6.025   13.406  18.944  1   35.162 ? 772  HOH B O   1 
HETATM 9240 O  O   . HOH H 4 .   ? 34.401  10.969  32.966  1   22.455 ? 773  HOH B O   1 
HETATM 9241 O  O   . HOH H 4 .   ? 10.103  -11.338 -2.027  1   29.135 ? 774  HOH B O   1 
HETATM 9242 O  O   . HOH H 4 .   ? -11.675 2.909   -4.793  1   24.604 ? 775  HOH B O   1 
HETATM 9243 O  O   . HOH H 4 .   ? -28.567 2.181   -10.884 1   27.572 ? 776  HOH B O   1 
HETATM 9244 O  O   . HOH H 4 .   ? 6.901   -8.981  -7.101  1   34.736 ? 777  HOH B O   1 
HETATM 9245 O  O   . HOH H 4 .   ? -7.889  -29.971 -9.54   1   33.919 ? 778  HOH B O   1 
HETATM 9246 O  O   . HOH H 4 .   ? -16.536 -31.734 4.52    1   38.193 ? 779  HOH B O   1 
HETATM 9247 O  O   . HOH H 4 .   ? -7.08   -14.383 18.702  1   21.472 ? 780  HOH B O   1 
HETATM 9248 O  O   . HOH H 4 .   ? -10.532 -1.045  -6.845  1   44.741 ? 781  HOH B O   1 
HETATM 9249 O  O   . HOH H 4 .   ? -14.081 5.599   23.745  1   19.11  ? 782  HOH B O   1 
HETATM 9250 O  O   . HOH H 4 .   ? -12.946 3.608   22.282  1   16.782 ? 783  HOH B O   1 
HETATM 9251 O  O   . HOH H 4 .   ? -36.159 -14.3   24.246  1   25.532 ? 784  HOH B O   1 
HETATM 9252 O  O   . HOH H 4 .   ? -25.951 -22.994 -18.302 1   29.412 ? 785  HOH B O   1 
HETATM 9253 O  O   . HOH H 4 .   ? -12.865 -19.392 -5.361  1   21.758 ? 786  HOH B O   1 
HETATM 9254 O  O   . HOH H 4 .   ? -16.036 -9.361  25.931  1   14.401 ? 787  HOH B O   1 
HETATM 9255 O  O   . HOH H 4 .   ? -0.246  -19.219 -10.099 1   32.887 ? 788  HOH B O   1 
HETATM 9256 O  O   . HOH H 4 .   ? 2.7     2.227   13.269  1   17.72  ? 789  HOH B O   1 
HETATM 9257 O  O   . HOH H 4 .   ? -4.87   -23.916 42.866  1   45.183 ? 790  HOH B O   1 
HETATM 9258 O  O   . HOH H 4 .   ? -41.028 -9.163  -1.843  1   36.821 ? 791  HOH B O   1 
HETATM 9259 O  O   . HOH H 4 .   ? -37.489 -20.74  17.989  1   34.784 ? 792  HOH B O   1 
HETATM 9260 O  O   . HOH H 4 .   ? -13.016 4.565   18.5    1   15.253 ? 793  HOH B O   1 
HETATM 9261 O  O   . HOH H 4 .   ? -19.43  -10.416 8.532   1   21.139 ? 794  HOH B O   1 
HETATM 9262 O  O   . HOH H 4 .   ? -8.836  -25.829 46.318  1   35.116 ? 795  HOH B O   1 
HETATM 9263 O  O   . HOH H 4 .   ? -23.686 -30.13  -4.785  1   42.313 ? 796  HOH B O   1 
HETATM 9264 O  O   . HOH H 4 .   ? -3.275  -17.185 -8.668  1   27.132 ? 797  HOH B O   1 
HETATM 9265 O  O   . HOH H 4 .   ? -41.036 0.674   0.238   1   36.504 ? 798  HOH B O   1 
HETATM 9266 O  O   . HOH H 4 .   ? -6.956  -13.442 10.842  1   15.523 ? 799  HOH B O   1 
HETATM 9267 O  O   . HOH H 4 .   ? -32.95  -27.648 -12.454 1   35.687 ? 800  HOH B O   1 
HETATM 9268 O  O   . HOH H 4 .   ? 1.092   -31.288 20.636  1   41.866 ? 801  HOH B O   1 
HETATM 9269 O  O   . HOH H 4 .   ? -22.974 -7.662  9.954   1   19.64  ? 802  HOH B O   1 
HETATM 9270 O  O   . HOH H 4 .   ? -7.452  -7.228  -12.556 1   28.179 ? 803  HOH B O   1 
HETATM 9271 O  O   . HOH H 4 .   ? -2.569  0.933   6.034   1   18.92  ? 804  HOH B O   1 
HETATM 9272 O  O   . HOH H 4 .   ? -24.077 -9.139  12.154  1   17.645 ? 805  HOH B O   1 
HETATM 9273 O  O   . HOH H 4 .   ? 7.34    -15.262 -6.617  1   44.142 ? 806  HOH B O   1 
HETATM 9274 O  O   . HOH H 4 .   ? -25.848 -17.235 24.767  1   27.905 ? 807  HOH B O   1 
HETATM 9275 O  O   . HOH H 4 .   ? -28.303 6.179   17.866  1   16.505 ? 808  HOH B O   1 
HETATM 9276 O  O   . HOH H 4 .   ? -9.967  -18.621 16.392  1   19.499 ? 809  HOH B O   1 
HETATM 9277 O  O   . HOH H 4 .   ? -19.102 -25.863 -11.9   1   29.915 ? 810  HOH B O   1 
HETATM 9278 O  O   . HOH H 4 .   ? -12.186 -1.624  28.019  1   13.755 ? 811  HOH B O   1 
HETATM 9279 O  O   . HOH H 4 .   ? -23.611 10.665  -2.926  1   29.754 ? 812  HOH B O   1 
HETATM 9280 O  O   . HOH H 4 .   ? 7.997   -21.309 10.159  1   31.27  ? 813  HOH B O   1 
HETATM 9281 O  O   . HOH H 4 .   ? 2.839   1.7     23.083  1   15.644 ? 814  HOH B O   1 
HETATM 9282 O  O   . HOH H 4 .   ? 3.768   -17.372 -5.196  1   30.116 ? 815  HOH B O   1 
HETATM 9283 O  O   . HOH H 4 .   ? -22.634 -30.789 -1.962  1   35.514 ? 816  HOH B O   1 
HETATM 9284 O  O   . HOH H 4 .   ? 21.063  19.948  38.501  1   23.403 ? 817  HOH B O   1 
HETATM 9285 O  O   . HOH H 4 .   ? 7.006   6.174   9.913   1   40.901 ? 818  HOH B O   1 
HETATM 9286 O  O   . HOH H 4 .   ? -24.762 1.937   17.573  1   14.597 ? 819  HOH B O   1 
HETATM 9287 O  O   . HOH H 4 .   ? -9.453  11.094  3.914   1   28.985 ? 820  HOH B O   1 
HETATM 9288 O  O   . HOH H 4 .   ? -11.05  -27.202 -8.628  1   31.964 ? 821  HOH B O   1 
HETATM 9289 O  O   . HOH H 4 .   ? -22.687 3.241   5.57    1   16.644 ? 822  HOH B O   1 
HETATM 9290 O  O   . HOH H 4 .   ? -25.233 -16.188 -19.806 1   33.8   ? 823  HOH B O   1 
HETATM 9291 O  O   . HOH H 4 .   ? -40.491 -4.156  24.984  1   26.846 ? 824  HOH B O   1 
HETATM 9292 O  O   . HOH H 4 .   ? -20.917 -12.744 23.046  1   17.744 ? 825  HOH B O   1 
HETATM 9293 O  O   . HOH H 4 .   ? -30.608 -21.053 31.055  1   35.196 ? 826  HOH B O   1 
HETATM 9294 O  O   . HOH H 4 .   ? -21.187 13.819  30.859  1   46.74  ? 827  HOH B O   1 
HETATM 9295 O  O   . HOH H 4 .   ? -7.888  -13.866 -6.45   1   22.088 ? 828  HOH B O   1 
HETATM 9296 O  O   . HOH H 4 .   ? -10.981 -3.447  22.808  1   16.596 ? 829  HOH B O   1 
HETATM 9297 O  O   . HOH H 4 .   ? -10.418 7.001   -3.537  1   26.933 ? 830  HOH B O   1 
HETATM 9298 O  O   . HOH H 4 .   ? -26.781 -12.939 34.066  1   32.666 ? 831  HOH B O   1 
HETATM 9299 O  O   . HOH H 4 .   ? 5.275   -5.028  -9.665  1   54.045 ? 832  HOH B O   1 
HETATM 9300 O  O   . HOH H 4 .   ? -7.927  -14.685 -12.774 1   27.028 ? 833  HOH B O   1 
HETATM 9301 O  O   . HOH H 4 .   ? -25.614 -5.25   26.146  1   15.894 ? 834  HOH B O   1 
HETATM 9302 O  O   . HOH H 4 .   ? -17.243 10.657  9.935   1   28.661 ? 835  HOH B O   1 
HETATM 9303 O  O   . HOH H 4 .   ? -12.55  -3.979  0.177   1   28.983 ? 836  HOH B O   1 
HETATM 9304 O  O   . HOH H 4 .   ? -37.239 1.317   -7.439  1   28.917 ? 837  HOH B O   1 
HETATM 9305 O  O   . HOH H 4 .   ? -2.5    -23.619 -5.031  1   27.618 ? 838  HOH B O   1 
HETATM 9306 O  O   . HOH H 4 .   ? -40.061 -15.163 -11.507 1   43.665 ? 839  HOH B O   1 
HETATM 9307 O  O   . HOH H 4 .   ? -16.843 -11.795 -2.396  1   18.537 ? 840  HOH B O   1 
HETATM 9308 O  O   . HOH H 4 .   ? -26.625 -7.079  24.3    1   16.461 ? 841  HOH B O   1 
HETATM 9309 O  O   . HOH H 4 .   ? -13.816 9.893   22.869  1   26.687 ? 842  HOH B O   1 
HETATM 9310 O  O   . HOH H 4 .   ? -32.145 -5.794  33.228  1   32.868 ? 843  HOH B O   1 
HETATM 9311 O  O   . HOH H 4 .   ? -0.51   11.987  20.657  1   39.417 ? 844  HOH B O   1 
HETATM 9312 O  O   . HOH H 4 .   ? -40.678 -12     5.3     1   30.667 ? 845  HOH B O   1 
HETATM 9313 O  O   . HOH H 4 .   ? -0.048  4.785   22.696  1   29.962 ? 846  HOH B O   1 
HETATM 9314 O  O   . HOH H 4 .   ? -11.303 -8.265  0.927   1   20.683 ? 847  HOH B O   1 
HETATM 9315 O  O   . HOH H 4 .   ? 13.542  -3.624  17.537  1   23.146 ? 848  HOH B O   1 
HETATM 9316 O  O   . HOH H 4 .   ? -23.624 -33.22  15.72   1   43.821 ? 849  HOH B O   1 
HETATM 9317 O  O   . HOH H 4 .   ? -10.915 -13.973 23.949  1   19.378 ? 850  HOH B O   1 
HETATM 9318 O  O   . HOH H 4 .   ? -28.638 -9.798  10.486  1   16.893 ? 851  HOH B O   1 
HETATM 9319 O  O   . HOH H 4 .   ? -34.483 -18.217 16.218  1   22.677 ? 852  HOH B O   1 
HETATM 9320 O  O   . HOH H 4 .   ? -13.645 -19.716 26.824  1   33.004 ? 853  HOH B O   1 
HETATM 9321 O  O   . HOH H 4 .   ? -8.821  -11.355 15.599  1   17.994 ? 854  HOH B O   1 
HETATM 9322 O  O   . HOH H 4 .   ? -18.048 -21.66  -16.41  1   32.871 ? 855  HOH B O   1 
HETATM 9323 O  O   . HOH H 4 .   ? -22.091 5.861   4.782   1   18.108 ? 856  HOH B O   1 
HETATM 9324 O  O   . HOH H 4 .   ? -28.086 -34.878 16.666  1   38.81  ? 857  HOH B O   1 
HETATM 9325 O  O   . HOH H 4 .   ? -17.776 -24.961 4.752   1   20.23  ? 858  HOH B O   1 
HETATM 9326 O  O   . HOH H 4 .   ? -7.099  -10.912 0.815   1   19.763 ? 859  HOH B O   1 
HETATM 9327 O  O   . HOH H 4 .   ? -11.224 7.67    8.27    1   17.909 ? 860  HOH B O   1 
HETATM 9328 O  O   . HOH H 4 .   ? -19.872 -11.366 41.373  1   39.418 ? 861  HOH B O   1 
HETATM 9329 O  O   . HOH H 4 .   ? -6.026  -7.78   0.601   1   21.756 ? 862  HOH B O   1 
HETATM 9330 O  O   . HOH H 4 .   ? -32.545 -21.1   -13.587 1   27.227 ? 863  HOH B O   1 
HETATM 9331 O  O   . HOH H 4 .   ? -25.596 -7.294  4.495   1   17.126 ? 864  HOH B O   1 
HETATM 9332 O  O   . HOH H 4 .   ? -22.835 -0.029  36.828  1   38.413 ? 865  HOH B O   1 
HETATM 9333 O  O   . HOH H 4 .   ? 0.734   -20.684 -2.462  1   28.18  ? 866  HOH B O   1 
HETATM 9334 O  O   . HOH H 4 .   ? -35.927 -26     -3.802  1   38.508 ? 867  HOH B O   1 
HETATM 9335 O  O   . HOH H 4 .   ? -25.398 -14.086 2.586   1   19.467 ? 868  HOH B O   1 
HETATM 9336 O  O   . HOH H 4 .   ? -24.543 7.156   22.504  1   16.48  ? 869  HOH B O   1 
HETATM 9337 O  O   . HOH H 4 .   ? 7.411   4.769   1.045   1   44.68  ? 870  HOH B O   1 
HETATM 9338 O  O   . HOH H 4 .   ? -27.755 -10.279 23.053  1   20.803 ? 871  HOH B O   1 
HETATM 9339 O  O   . HOH H 4 .   ? -41.919 -15.879 3.476   1   36.188 ? 872  HOH B O   1 
HETATM 9340 O  O   . HOH H 4 .   ? -7.683  -28.447 -5.605  1   25.229 ? 873  HOH B O   1 
HETATM 9341 O  O   . HOH H 4 .   ? -29.994 -5.255  7.572   1   16.501 ? 874  HOH B O   1 
HETATM 9342 O  O   . HOH H 4 .   ? -21.234 -24.669 -10.778 1   24.959 ? 875  HOH B O   1 
HETATM 9343 O  O   . HOH H 4 .   ? -24.795 -5.914  34.958  1   33.278 ? 876  HOH B O   1 
HETATM 9344 O  O   . HOH H 4 .   ? -30.383 -18.269 21.192  1   22.809 ? 877  HOH B O   1 
HETATM 9345 O  O   . HOH H 4 .   ? -39.028 3.221   24.72   1   24.446 ? 878  HOH B O   1 
HETATM 9346 O  O   . HOH H 4 .   ? 8.049   8.239   2.239   1   37.413 ? 879  HOH B O   1 
HETATM 9347 O  O   . HOH H 4 .   ? -28.831 -8.296  27.146  1   16.321 ? 880  HOH B O   1 
HETATM 9348 O  O   . HOH H 4 .   ? -17.938 -1.035  19.926  1   13.95  ? 881  HOH B O   1 
HETATM 9349 O  O   . HOH H 4 .   ? -4.549  10.603  8.362   1   26.107 ? 882  HOH B O   1 
HETATM 9350 O  O   . HOH H 4 .   ? -8.886  7.865   6.853   1   22.055 ? 883  HOH B O   1 
HETATM 9351 O  O   . HOH H 4 .   ? -16.946 -12.287 1.234   1   17.643 ? 884  HOH B O   1 
HETATM 9352 O  O   . HOH H 4 .   ? -15.336 -26.315 -12.823 1   47.877 ? 885  HOH B O   1 
HETATM 9353 O  O   . HOH H 4 .   ? -32.083 -4.763  13.221  1   19.951 ? 886  HOH B O   1 
HETATM 9354 O  O   . HOH H 4 .   ? -9.335  -11.128 -14.75  1   26.072 ? 887  HOH B O   1 
HETATM 9355 O  O   . HOH H 4 .   ? -31.022 -9.864  -13.236 1   23.459 ? 888  HOH B O   1 
HETATM 9356 O  O   . HOH H 4 .   ? -37.773 6.536   9.853   1   44.989 ? 889  HOH B O   1 
HETATM 9357 O  O   . HOH H 4 .   ? 4.178   4.391   15.465  1   19.978 ? 890  HOH B O   1 
HETATM 9358 O  O   . HOH H 4 .   ? -37.672 -0.653  -1.795  1   25.06  ? 891  HOH B O   1 
HETATM 9359 O  O   . HOH H 4 .   ? 10.54   -10.948 1.759   1   34.072 ? 892  HOH B O   1 
HETATM 9360 O  O   . HOH H 4 .   ? 12.825  -8.936  -0.23   1   43.6   ? 893  HOH B O   1 
HETATM 9361 O  O   . HOH H 4 .   ? -19.99  -23.127 -14.838 1   31.663 ? 894  HOH B O   1 
HETATM 9362 O  O   . HOH H 4 .   ? -32.9   -32.959 5.303   1   47.428 ? 895  HOH B O   1 
HETATM 9363 O  O   . HOH H 4 .   ? -17.447 -0.082  28.276  1   14.476 ? 896  HOH B O   1 
HETATM 9364 O  O   . HOH H 4 .   ? -19.108 13.301  12.512  1   26.924 ? 897  HOH B O   1 
HETATM 9365 O  O   . HOH H 4 .   ? -20.679 -1.419  19.949  1   13.241 ? 898  HOH B O   1 
HETATM 9366 O  O   . HOH H 4 .   ? -12.211 -21.909 14.663  1   20.786 ? 899  HOH B O   1 
HETATM 9367 O  O   . HOH H 4 .   ? 12.442  -8.643  3.462   1   34.067 ? 900  HOH B O   1 
HETATM 9368 O  O   . HOH H 4 .   ? -7.523  11.007  16.45   1   26.571 ? 901  HOH B O   1 
HETATM 9369 O  O   . HOH H 4 .   ? -11.524 -8.354  30.059  1   14.932 ? 902  HOH B O   1 
HETATM 9370 O  O   . HOH H 4 .   ? 7.164   -4.575  -3.122  1   32.714 ? 903  HOH B O   1 
HETATM 9371 O  O   . HOH H 4 .   ? -4.417  -7.927  -3.557  1   23.18  ? 904  HOH B O   1 
HETATM 9372 O  O   . HOH H 4 .   ? -12.564 -12.969 -17.855 1   33.742 ? 905  HOH B O   1 
HETATM 9373 O  O   . HOH H 4 .   ? -18.664 -22.027 23.514  1   30.164 ? 906  HOH B O   1 
HETATM 9374 O  O   . HOH H 4 .   ? -18.35  -9.838  38.427  1   30.95  ? 907  HOH B O   1 
HETATM 9375 O  O   . HOH H 4 .   ? -34.219 -15.216 -16.263 1   41.273 ? 908  HOH B O   1 
HETATM 9376 O  O   . HOH H 4 .   ? 33.183  9.053   28      1   32.868 ? 909  HOH B O   1 
HETATM 9377 O  O   . HOH H 4 .   ? -30.887 -28.606 4.976   1   30.284 ? 910  HOH B O   1 
HETATM 9378 O  O   . HOH H 4 .   ? -25.356 -6.84   18.318  1   15.197 ? 911  HOH B O   1 
HETATM 9379 O  O   . HOH H 4 .   ? 14.907  12.345  22.958  1   21.654 ? 912  HOH B O   1 
HETATM 9380 O  O   . HOH H 4 .   ? -28.939 9.646   5.085   1   31.919 ? 913  HOH B O   1 
HETATM 9381 O  O   . HOH H 4 .   ? -14.344 -13.968 4.315   1   17.386 ? 914  HOH B O   1 
HETATM 9382 O  O   . HOH H 4 .   ? -7.895  -8.063  2.717   1   18.439 ? 915  HOH B O   1 
HETATM 9383 O  O   . HOH H 4 .   ? 7.75    -4.401  6.416   1   23.568 ? 916  HOH B O   1 
HETATM 9384 O  O   . HOH H 4 .   ? -30.792 -5.29   -17.249 1   30.734 ? 917  HOH B O   1 
HETATM 9385 O  O   . HOH H 4 .   ? -23.131 -7.996  5.959   1   17.244 ? 918  HOH B O   1 
HETATM 9386 O  O   . HOH H 4 .   ? -14.113 -12.788 -0.107  1   23.411 ? 919  HOH B O   1 
HETATM 9387 O  O   . HOH H 4 .   ? 19.54   16.225  29.991  1   23.335 ? 920  HOH B O   1 
HETATM 9388 O  O   . HOH H 4 .   ? 2.816   13.452  10.666  1   41.215 ? 921  HOH B O   1 
HETATM 9389 O  O   . HOH H 4 .   ? -22.452 -16.093 23.438  1   22.769 ? 922  HOH B O   1 
HETATM 9390 O  O   . HOH H 4 .   ? -6.482  -4.349  -10.365 1   26.234 ? 923  HOH B O   1 
HETATM 9391 O  O   . HOH H 4 .   ? -1.679  -27.273 -12.641 1   44.146 ? 924  HOH B O   1 
HETATM 9392 O  O   . HOH H 4 .   ? -16.064 -5.104  -12.219 1   22.076 ? 925  HOH B O   1 
HETATM 9393 O  O   . HOH H 4 .   ? -15.819 -13.94  16.512  1   19.719 ? 926  HOH B O   1 
HETATM 9394 O  O   . HOH H 4 .   ? -33.541 -3.876  10.959  1   16.911 ? 927  HOH B O   1 
HETATM 9395 O  O   . HOH H 4 .   ? 1.874   -26.117 7.444   1   25.052 ? 928  HOH B O   1 
HETATM 9396 O  O   . HOH H 4 .   ? -42.062 -9.005  24.643  1   35.69  ? 929  HOH B O   1 
HETATM 9397 O  O   . HOH H 4 .   ? -13.021 13.529  22.143  1   46.058 ? 930  HOH B O   1 
HETATM 9398 O  O   . HOH H 4 .   ? -8.732  -11.331 8.555   1   17.685 ? 931  HOH B O   1 
HETATM 9399 O  O   . HOH H 4 .   ? -10.876 -10.63  -0.746  1   20.937 ? 932  HOH B O   1 
HETATM 9400 O  O   . HOH H 4 .   ? 4.299   -13.463 24.093  1   26.985 ? 933  HOH B O   1 
HETATM 9401 O  O   . HOH H 4 .   ? 2.226   -23.866 22.08   1   44.082 ? 934  HOH B O   1 
HETATM 9402 O  O   . HOH H 4 .   ? -8.912  0.853   -0.5    1   22.271 ? 935  HOH B O   1 
HETATM 9403 O  O   . HOH H 4 .   ? 6.45    -11.247 -8.284  1   32.33  ? 936  HOH B O   1 
HETATM 9404 O  O   . HOH H 4 .   ? -14.432 10.044  19.293  1   21.256 ? 937  HOH B O   1 
HETATM 9405 O  O   . HOH H 4 .   ? -27.486 -31.11  10.114  1   33.659 ? 938  HOH B O   1 
HETATM 9406 O  O   . HOH H 4 .   ? -14.305 -18.473 13.494  1   20.597 ? 939  HOH B O   1 
HETATM 9407 O  O   . HOH H 4 .   ? -19.929 -34.088 -1.649  1   42.569 ? 940  HOH B O   1 
HETATM 9408 O  O   . HOH H 4 .   ? -39.011 -18.573 -8.988  1   43.81  ? 941  HOH B O   1 
HETATM 9409 O  O   . HOH H 4 .   ? -29.053 0.121   13.879  1   19.344 ? 942  HOH B O   1 
HETATM 9410 O  O   . HOH H 4 .   ? -17.842 -14.501 28.893  1   27.459 ? 943  HOH B O   1 
HETATM 9411 O  O   . HOH H 4 .   ? -8.522  -3.588  -6.283  1   46.58  ? 944  HOH B O   1 
HETATM 9412 O  O   . HOH H 4 .   ? 10.283  -1.863  3.668   1   37.852 ? 945  HOH B O   1 
HETATM 9413 O  O   . HOH H 4 .   ? -23.106 -11.466 11.238  1   22.779 ? 946  HOH B O   1 
HETATM 9414 O  O   . HOH H 4 .   ? 7.497   -1.216  4.475   1   20.24  ? 947  HOH B O   1 
HETATM 9415 O  O   . HOH H 4 .   ? 21.41   14.123  24.549  1   34.361 ? 948  HOH B O   1 
HETATM 9416 O  O   . HOH H 4 .   ? 11.388  16.957  17.337  1   30.866 ? 949  HOH B O   1 
HETATM 9417 O  O   . HOH H 4 .   ? -42.869 -9.46   10.196  1   28.919 ? 950  HOH B O   1 
HETATM 9418 O  O   . HOH H 4 .   ? -9.42   -5.341  -12.906 1   26.264 ? 951  HOH B O   1 
HETATM 9419 O  O   . HOH H 4 .   ? -11.467 -4.955  -3.569  1   24.978 ? 952  HOH B O   1 
HETATM 9420 O  O   . HOH H 4 .   ? 20.956  23.213  34.957  1   40.321 ? 953  HOH B O   1 
HETATM 9421 O  O   . HOH H 4 .   ? -27.559 -21.684 -14.065 1   24.022 ? 954  HOH B O   1 
HETATM 9422 O  O   . HOH H 4 .   ? -30.262 -12.596 26.498  1   19.272 ? 955  HOH B O   1 
HETATM 9423 O  O   . HOH H 4 .   ? 12.956  -3.587  10.709  1   38.348 ? 956  HOH B O   1 
HETATM 9424 O  O   . HOH H 4 .   ? -23.343 -3.764  23.55   1   13.851 ? 957  HOH B O   1 
HETATM 9425 O  O   . HOH H 4 .   ? -18.542 12.703  2.569   1   60.968 ? 958  HOH B O   1 
HETATM 9426 O  O   . HOH H 4 .   ? -4.2    -29.801 18.242  1   39.034 ? 959  HOH B O   1 
HETATM 9427 O  O   . HOH H 4 .   ? -5.605  -5.214  0.046   1   26.775 ? 960  HOH B O   1 
HETATM 9428 O  O   . HOH H 4 .   ? -23.163 -5.105  27.294  1   16.694 ? 961  HOH B O   1 
HETATM 9429 O  O   . HOH H 4 .   ? -23.356 -24.205 -22.118 1   49.256 ? 962  HOH B O   1 
HETATM 9430 O  O   . HOH H 4 .   ? -20.215 -11.398 20.833  1   16.381 ? 963  HOH B O   1 
HETATM 9431 O  O   . HOH H 4 .   ? -8.508  -15.536 22.523  1   30.493 ? 964  HOH B O   1 
HETATM 9432 O  O   . HOH H 4 .   ? 7.632   -0.596  23.043  1   15.645 ? 965  HOH B O   1 
HETATM 9433 O  O   . HOH H 4 .   ? -21.89  -3.355  33.629  1   16.626 ? 966  HOH B O   1 
HETATM 9434 O  O   . HOH H 4 .   ? -28.767 -5.718  18.353  1   17.505 ? 967  HOH B O   1 
HETATM 9435 O  O   . HOH H 4 .   ? -20.75  -27.546 9.773   1   25.541 ? 968  HOH B O   1 
HETATM 9436 O  O   . HOH H 4 .   ? -27.815 -7.277  20.743  1   15.387 ? 969  HOH B O   1 
HETATM 9437 O  O   . HOH H 4 .   ? -37.459 -12.911 -10.027 1   24.637 ? 970  HOH B O   1 
HETATM 9438 O  O   . HOH H 4 .   ? -13.643 -4.65   2.993   1   19.861 ? 971  HOH B O   1 
HETATM 9439 O  O   . HOH H 4 .   ? -27.169 -26.721 13.616  1   27.102 ? 972  HOH B O   1 
HETATM 9440 O  O   . HOH H 4 .   ? -25.5   6.223   29.358  1   17.869 ? 973  HOH B O   1 
HETATM 9441 O  O   . HOH H 4 .   ? -23.146 6.252   35.104  1   38.451 ? 974  HOH B O   1 
HETATM 9442 O  O   . HOH H 4 .   ? -46.15  -10.207 19.525  1   30.642 ? 975  HOH B O   1 
HETATM 9443 O  O   . HOH H 4 .   ? 3.842   -23.14  11.451  1   27.838 ? 976  HOH B O   1 
HETATM 9444 O  O   . HOH H 4 .   ? 4.976   10.731  16.318  1   29.142 ? 977  HOH B O   1 
HETATM 9445 O  O   . HOH H 4 .   ? 8.956   1.691   10.487  1   28.99  ? 978  HOH B O   1 
HETATM 9446 O  O   . HOH H 4 .   ? -45.789 -8.335  -0.251  1   53.641 ? 979  HOH B O   1 
HETATM 9447 O  O   . HOH H 4 .   ? 3.344   11.365  22.087  1   26.906 ? 980  HOH B O   1 
HETATM 9448 O  O   . HOH H 4 .   ? 1.322   -17.973 -5.78   1   33.406 ? 981  HOH B O   1 
HETATM 9449 O  O   . HOH H 4 .   ? -15.294 -18.522 -8.7    1   27.472 ? 982  HOH B O   1 
HETATM 9450 O  O   . HOH H 4 .   ? -24.024 -4.708  32.681  1   17.146 ? 983  HOH B O   1 
HETATM 9451 O  O   . HOH H 4 .   ? -15.352 -6.263  1.926   1   31.987 ? 984  HOH B O   1 
HETATM 9452 O  O   . HOH H 4 .   ? -33.993 -9.352  3.026   1   27.142 ? 985  HOH B O   1 
HETATM 9453 O  O   . HOH H 4 .   ? -19.365 12.822  5.626   1   44.834 ? 986  HOH B O   1 
HETATM 9454 O  O   . HOH H 4 .   ? 3.497   -7.232  0.276   1   25.95  ? 987  HOH B O   1 
HETATM 9455 O  O   . HOH H 4 .   ? -39.792 -16.383 10.812  1   27.65  ? 988  HOH B O   1 
HETATM 9456 O  O   . HOH H 4 .   ? -25.919 -4.679  16.696  1   15.931 ? 989  HOH B O   1 
HETATM 9457 O  O   . HOH H 4 .   ? -14.188 12.45   16.718  1   24.328 ? 990  HOH B O   1 
HETATM 9458 O  O   . HOH H 4 .   ? 5.04    -8.023  21.649  1   17.464 ? 991  HOH B O   1 
HETATM 9459 O  O   . HOH H 4 .   ? -10.557 -19.708 13.928  1   19.669 ? 992  HOH B O   1 
HETATM 9460 O  O   . HOH H 4 .   ? -6.35   2.601   21.219  1   14.676 ? 993  HOH B O   1 
HETATM 9461 O  O   . HOH H 4 .   ? -5.75   -16.386 21.359  1   30.51  ? 994  HOH B O   1 
HETATM 9462 O  O   . HOH H 4 .   ? -22.941 -8.065  35.92   1   35.016 ? 995  HOH B O   1 
HETATM 9463 O  O   . HOH H 4 .   ? -35.121 -9.506  31.014  1   25.938 ? 996  HOH B O   1 
HETATM 9464 O  O   . HOH H 4 .   ? -12.505 -18.511 -9.415  1   23.475 ? 997  HOH B O   1 
HETATM 9465 O  O   . HOH H 4 .   ? -5.811  3.457   25.458  1   27.541 ? 998  HOH B O   1 
HETATM 9466 O  O   . HOH H 4 .   ? -11.171 4.481   -2.569  1   19.884 ? 999  HOH B O   1 
HETATM 9467 O  O   . HOH H 4 .   ? -6.311  -9.12   -1.749  1   20.803 ? 1000 HOH B O   1 
HETATM 9468 O  O   . HOH H 4 .   ? -11.072 -19.778 21.003  1   34.152 ? 1001 HOH B O   1 
HETATM 9469 O  O   . HOH H 4 .   ? 11.591  -11.721 -4.229  1   49.928 ? 1002 HOH B O   1 
HETATM 9470 O  O   . HOH H 4 .   ? -28.829 -12.368 20.563  1   16.055 ? 1003 HOH B O   1 
HETATM 9471 O  O   . HOH H 4 .   ? -3.705  -12.949 27.286  1   19.303 ? 1004 HOH B O   1 
HETATM 9472 O  O   . HOH H 4 .   ? -29.786 -30.153 6.671   1   27.931 ? 1005 HOH B O   1 
HETATM 9473 O  O   . HOH H 4 .   ? -11.104 -19.591 -7.337  1   23.747 ? 1006 HOH B O   1 
HETATM 9474 O  O   . HOH H 4 .   ? -33.501 -1.449  9.691   1   16.069 ? 1007 HOH B O   1 
HETATM 9475 O  O   . HOH H 4 .   ? -10.347 -1.395  1.823   1   17.925 ? 1008 HOH B O   1 
HETATM 9476 O  O   . HOH H 4 .   ? -31.284 -0.416  11.029  1   18.144 ? 1009 HOH B O   1 
HETATM 9477 O  O   . HOH H 4 .   ? -42.639 -13.238 1.465   1   36.369 ? 1010 HOH B O   1 
HETATM 9478 O  O   . HOH H 4 .   ? 20.391  21.68   30.17   1   35.161 ? 1011 HOH B O   1 
HETATM 9479 O  O   . HOH H 4 .   ? -0.899  -29.493 -1.645  1   38.381 ? 1012 HOH B O   1 
HETATM 9480 O  O   . HOH H 4 .   ? -10.042 4.162   24.832  1   20.425 ? 1013 HOH B O   1 
HETATM 9481 O  O   . HOH H 4 .   ? 6.532   4.291   13.97   1   30.509 ? 1014 HOH B O   1 
HETATM 9482 O  O   . HOH H 4 .   ? -17.441 -10.666 -4.92   1   19.685 ? 1015 HOH B O   1 
HETATM 9483 O  O   . HOH H 4 .   ? -23.736 -25.895 -11.084 1   29.486 ? 1016 HOH B O   1 
HETATM 9484 O  O   . HOH H 4 .   ? -16.023 -11.741 -15.84  1   26.152 ? 1017 HOH B O   1 
HETATM 9485 O  O   . HOH H 4 .   ? -18.666 11.619  0.415   1   47.837 ? 1018 HOH B O   1 
HETATM 9486 O  O   . HOH H 4 .   ? -24.877 -23.897 -9.315  1   28.393 ? 1019 HOH B O   1 
HETATM 9487 O  O   . HOH H 4 .   ? 0.16    -27.977 0.415   1   28.806 ? 1020 HOH B O   1 
HETATM 9488 O  O   . HOH H 4 .   ? -31.863 -9.372  32.814  1   23.752 ? 1021 HOH B O   1 
HETATM 9489 O  O   . HOH H 4 .   ? -19.545 4.212   36.758  1   33.995 ? 1022 HOH B O   1 
HETATM 9490 O  O   . HOH H 4 .   ? -26.745 -15.5   31.587  1   35.702 ? 1023 HOH B O   1 
HETATM 9491 O  O   . HOH H 4 .   ? -38.226 -5.463  -5.98   1   29.771 ? 1024 HOH B O   1 
HETATM 9492 O  O   . HOH H 4 .   ? -36.766 -18.308 -3.453  1   27.95  ? 1025 HOH B O   1 
HETATM 9493 O  O   . HOH H 4 .   ? -45.067 -10.201 12.155  1   30.668 ? 1026 HOH B O   1 
HETATM 9494 O  O   . HOH H 4 .   ? -38.838 5.741   21.575  1   31.119 ? 1027 HOH B O   1 
HETATM 9495 O  O   . HOH H 4 .   ? -11.564 -31.911 -1.455  1   37.907 ? 1028 HOH B O   1 
HETATM 9496 O  O   . HOH H 4 .   ? -26.167 5.799   -12.717 1   35.609 ? 1029 HOH B O   1 
HETATM 9497 O  O   . HOH H 4 .   ? -31.141 6.683   -11.64  1   40.752 ? 1030 HOH B O   1 
HETATM 9498 O  O   . HOH H 4 .   ? -32.598 0.112   18.341  1   20.25  ? 1031 HOH B O   1 
HETATM 9499 O  O   . HOH H 4 .   ? -26.043 -6.661  -16.346 1   34.594 ? 1032 HOH B O   1 
HETATM 9500 O  O   . HOH H 4 .   ? -36.969 -16.625 19.7    1   25.233 ? 1033 HOH B O   1 
HETATM 9501 O  O   . HOH H 4 .   ? -13.398 -5.517  -1.791  1   19.851 ? 1034 HOH B O   1 
HETATM 9502 O  O   . HOH H 4 .   ? 10.157  -7.476  -3.688  1   42.415 ? 1035 HOH B O   1 
HETATM 9503 O  O   . HOH H 4 .   ? 36.837  11.518  39.363  1   28.451 ? 1036 HOH B O   1 
HETATM 9504 O  O   . HOH H 4 .   ? -13.633 11.483  1.108   1   46.449 ? 1037 HOH B O   1 
HETATM 9505 O  O   . HOH H 4 .   ? 6.253   18.958  27.093  1   29.083 ? 1038 HOH B O   1 
HETATM 9506 O  O   . HOH H 4 .   ? 19.793  12.015  37.251  1   23.405 ? 1039 HOH B O   1 
HETATM 9507 O  O   . HOH H 4 .   ? -7.969  -7.044  23.517  1   19.773 ? 1040 HOH B O   1 
HETATM 9508 O  O   . HOH H 4 .   ? -11.376 10.441  -2.46   1   37.29  ? 1041 HOH B O   1 
HETATM 9509 O  O   . HOH H 4 .   ? -12.79  -22.992 -14.216 1   39.573 ? 1042 HOH B O   1 
HETATM 9510 O  O   . HOH H 4 .   ? -41.548 -5.239  -16.687 1   46.787 ? 1043 HOH B O   1 
HETATM 9511 O  O   . HOH H 4 .   ? -12.853 7.05    19.789  1   22.192 ? 1044 HOH B O   1 
HETATM 9512 O  O   . HOH H 4 .   ? 2.097   -4.242  1.521   1   24.854 ? 1045 HOH B O   1 
HETATM 9513 O  O   . HOH H 4 .   ? -31.793 -13.401 15.287  1   17.173 ? 1046 HOH B O   1 
HETATM 9514 O  O   . HOH H 4 .   ? -21.552 11.591  12.074  1   29.436 ? 1047 HOH B O   1 
HETATM 9515 O  O   . HOH H 4 .   ? -10.45  -28.695 -6.25   1   31.847 ? 1048 HOH B O   1 
HETATM 9516 O  O   . HOH H 4 .   ? -34.803 -6.624  3.316   1   20.97  ? 1049 HOH B O   1 
HETATM 9517 O  O   . HOH H 4 .   ? -31.377 7.574   23.607  1   32.832 ? 1050 HOH B O   1 
HETATM 9518 O  O   . HOH H 4 .   ? -15.483 -21.488 25.799  1   35.257 ? 1051 HOH B O   1 
HETATM 9519 O  O   . HOH H 4 .   ? 11.394  19.528  28.656  1   35.594 ? 1052 HOH B O   1 
HETATM 9520 O  O   . HOH H 4 .   ? -8.502  5.401   0.344   1   23.201 ? 1053 HOH B O   1 
HETATM 9521 O  O   . HOH H 4 .   ? -11.837 -18.05  12.13   1   18.368 ? 1054 HOH B O   1 
HETATM 9522 O  O   . HOH H 4 .   ? -40.619 -1.999  11.86   1   22.03  ? 1055 HOH B O   1 
HETATM 9523 O  O   . HOH H 4 .   ? -27.94  -30.343 -10.803 1   32.588 ? 1056 HOH B O   1 
HETATM 9524 O  O   . HOH H 4 .   ? -0.158  7.187   2.01    1   24.747 ? 1057 HOH B O   1 
HETATM 9525 O  O   . HOH H 4 .   ? -37.827 -6.927  -8.457  1   48.647 ? 1058 HOH B O   1 
HETATM 9526 O  O   . HOH H 4 .   ? -9.885  -8.38   21.916  1   16.044 ? 1059 HOH B O   1 
HETATM 9527 O  O   . HOH H 4 .   ? -4.301  -29.882 -4.062  1   40.633 ? 1060 HOH B O   1 
HETATM 9528 O  O   . HOH H 4 .   ? -40.838 -9.08   -4.741  1   50     ? 1061 HOH B O   1 
HETATM 9529 O  O   . HOH H 4 .   ? -34.286 5.796   22.192  1   36.968 ? 1062 HOH B O   1 
HETATM 9530 O  O   . HOH H 4 .   ? -37.019 -4.47   26.601  1   22.589 ? 1063 HOH B O   1 
HETATM 9531 O  O   . HOH H 4 .   ? -27.378 8.946   8.921   1   20.311 ? 1064 HOH B O   1 
HETATM 9532 O  O   . HOH H 4 .   ? -19.956 -11.337 -19.596 1   45.486 ? 1065 HOH B O   1 
HETATM 9533 O  O   . HOH H 4 .   ? -16.616 -8.438  1.747   1   25.384 ? 1066 HOH B O   1 
HETATM 9534 O  O   . HOH H 4 .   ? -34.434 -27.962 0.143   1   29.683 ? 1067 HOH B O   1 
HETATM 9535 O  O   . HOH H 4 .   ? -1.72   -13.1   -12.816 1   32.755 ? 1068 HOH B O   1 
HETATM 9536 O  O   . HOH H 4 .   ? 5.921   -22.764 9.535   1   25.749 ? 1069 HOH B O   1 
HETATM 9537 O  O   . HOH H 4 .   ? -41.815 -4.434  9.089   1   26.397 ? 1070 HOH B O   1 
HETATM 9538 O  O   . HOH H 4 .   ? 10.801  18.38   21.621  1   24.804 ? 1071 HOH B O   1 
HETATM 9539 O  O   . HOH H 4 .   ? -40.811 8.18    15.961  1   41.162 ? 1072 HOH B O   1 
HETATM 9540 O  O   . HOH H 4 .   ? 16.945  18.283  24.822  1   24.525 ? 1073 HOH B O   1 
HETATM 9541 O  O   . HOH H 4 .   ? -22.413 -1.198  7.871   1   16.302 ? 1074 HOH B O   1 
HETATM 9542 O  O   . HOH H 4 .   ? -36.993 -26.374 -11.589 1   39.36  ? 1075 HOH B O   1 
HETATM 9543 O  O   . HOH H 4 .   ? 5.087   -2.392  -6.134  1   46.343 ? 1076 HOH B O   1 
HETATM 9544 O  O   . HOH H 4 .   ? 9.605   16.619  19.597  1   23.712 ? 1077 HOH B O   1 
HETATM 9545 O  O   . HOH H 4 .   ? -35.015 3.297   -7.075  1   28.471 ? 1078 HOH B O   1 
HETATM 9546 O  O   . HOH H 4 .   ? 10.537  -5.857  19.599  1   21.123 ? 1079 HOH B O   1 
HETATM 9547 O  O   . HOH H 4 .   ? -17.952 13.776  -6.108  1   65.135 ? 1080 HOH B O   1 
HETATM 9548 O  O   . HOH H 4 .   ? -19.368 -31.874 -7.172  1   31.872 ? 1081 HOH B O   1 
HETATM 9549 O  O   . HOH H 4 .   ? -28.824 5.947   -9.68   1   34.815 ? 1082 HOH B O   1 
HETATM 9550 O  O   . HOH H 4 .   ? -1.662  11.18   2.471   1   31.131 ? 1083 HOH B O   1 
HETATM 9551 O  O   . HOH H 4 .   ? 22.099  22.078  32.934  1   27.485 ? 1084 HOH B O   1 
HETATM 9552 O  O   . HOH H 4 .   ? -27.561 -4.468  5.198   1   17.117 ? 1085 HOH B O   1 
HETATM 9553 O  O   . HOH H 4 .   ? 31.29   10.464  35.729  1   17.946 ? 1086 HOH B O   1 
HETATM 9554 O  O   . HOH H 4 .   ? -18.784 -30.695 9.357   1   39.516 ? 1087 HOH B O   1 
HETATM 9555 O  O   . HOH H 4 .   ? -13.43  -10.765 -16.121 1   26.472 ? 1088 HOH B O   1 
HETATM 9556 O  O   . HOH H 4 .   ? -17.744 8.365   -10.942 1   32.378 ? 1089 HOH B O   1 
HETATM 9557 O  O   . HOH H 4 .   ? -25.483 -32.024 6.602   1   30.296 ? 1090 HOH B O   1 
HETATM 9558 O  O   . HOH H 4 .   ? 1.292   9.227   3.325   1   25.093 ? 1091 HOH B O   1 
HETATM 9559 O  O   . HOH H 4 .   ? 11.319  -8.686  18.144  1   24.313 ? 1092 HOH B O   1 
HETATM 9560 O  O   . HOH H 4 .   ? -34.929 -6.629  30.532  1   25.01  ? 1093 HOH B O   1 
HETATM 9561 O  O   . HOH H 4 .   ? -19.898 -1.547  -14.172 1   43.176 ? 1094 HOH B O   1 
HETATM 9562 O  O   . HOH H 4 .   ? -11.081 -31.253 -3.554  1   44.394 ? 1095 HOH B O   1 
HETATM 9563 O  O   . HOH H 4 .   ? -7.435  9.408   20.388  1   33.451 ? 1096 HOH B O   1 
HETATM 9564 O  O   . HOH H 4 .   ? -23.72  -25.779 13.1    1   28.435 ? 1097 HOH B O   1 
HETATM 9565 O  O   . HOH H 4 .   ? -8.243  -3.231  1.32    1   32.612 ? 1098 HOH B O   1 
HETATM 9566 O  O   . HOH H 4 .   ? 2.941   9.214   14.381  1   32.299 ? 1099 HOH B O   1 
HETATM 9567 O  O   . HOH H 4 .   ? -0.344  -4.328  -0.428  1   29.542 ? 1100 HOH B O   1 
HETATM 9568 O  O   . HOH H 4 .   ? -11.761 -16.907 24.668  1   28.404 ? 1101 HOH B O   1 
HETATM 9569 O  O   . HOH H 4 .   ? 0.379   6.953   20.857  1   30.966 ? 1102 HOH B O   1 
HETATM 9570 O  O   . HOH H 4 .   ? 1.673   -1.61   -0.042  1   27.639 ? 1103 HOH B O   1 
HETATM 9571 O  O   . HOH H 4 .   ? -10.131 10.174  22.142  1   30.509 ? 1104 HOH B O   1 
HETATM 9572 O  O   . HOH H 4 .   ? -21.906 8.923   32.98   1   42.398 ? 1105 HOH B O   1 
HETATM 9573 O  O   . HOH H 4 .   ? -45.061 -14.76  14.871  1   42.047 ? 1106 HOH B O   1 
HETATM 9574 O  O   . HOH H 4 .   ? -8.884  10.6    9.787   1   34.366 ? 1107 HOH B O   1 
HETATM 9575 O  O   . HOH H 4 .   ? -11.901 -15.229 11.279  1   17.466 ? 1108 HOH B O   1 
HETATM 9576 O  O   . HOH H 4 .   ? -41.653 -4.838  4.013   1   29.363 ? 1109 HOH B O   1 
HETATM 9577 O  O   . HOH H 4 .   ? -6.052  -15.425 43.121  1   20.218 ? 1110 HOH B O   1 
HETATM 9578 O  O   . HOH H 4 .   ? -18.243 -10.522 22.747  1   21.145 ? 1111 HOH B O   1 
HETATM 9579 O  O   . HOH H 4 .   ? -19.452 5.173   33.624  1   26.066 ? 1112 HOH B O   1 
HETATM 9580 O  O   . HOH H 4 .   ? -24.775 -16.778 30.175  1   33.545 ? 1113 HOH B O   1 
HETATM 9581 O  O   . HOH H 4 .   ? 2.321   -19.407 14.973  1   25.534 ? 1114 HOH B O   1 
HETATM 9582 O  O   . HOH H 4 .   ? -21.649 -25.533 11.163  1   25.399 ? 1115 HOH B O   1 
HETATM 9583 O  O   . HOH H 4 .   ? 12.157  -8.288  10.761  1   32.945 ? 1116 HOH B O   1 
HETATM 9584 O  O   . HOH H 4 .   ? -30.163 -29.3   0.097   1   37.094 ? 1117 HOH B O   1 
HETATM 9585 O  O   . HOH H 4 .   ? -40.158 -1.23   14.647  1   19.177 ? 1118 HOH B O   1 
HETATM 9586 O  O   . HOH H 4 .   ? -1.879  7.239   16.629  1   25.624 ? 1119 HOH B O   1 
HETATM 9587 O  O   . HOH H 4 .   ? -11.422 6.419   24.167  1   23.478 ? 1120 HOH B O   1 
HETATM 9588 O  O   . HOH H 4 .   ? -25.512 9.908   -0.639  1   38.732 ? 1121 HOH B O   1 
HETATM 9589 O  O   . HOH H 4 .   ? -42.086 -15.499 9.664   1   39.036 ? 1122 HOH B O   1 
HETATM 9590 O  O   . HOH H 4 .   ? -34.582 4.406   4.827   1   40.519 ? 1123 HOH B O   1 
HETATM 9591 O  O   . HOH H 4 .   ? -36.437 -18.35  -8.309  1   27.119 ? 1124 HOH B O   1 
HETATM 9592 O  O   . HOH H 4 .   ? 5.437   -0.033  12.055  1   19.643 ? 1125 HOH B O   1 
HETATM 9593 O  O   . HOH H 4 .   ? -19.448 3.946   -12.134 1   27.462 ? 1126 HOH B O   1 
HETATM 9594 O  O   . HOH H 4 .   ? -40.423 -16.795 -0.007  1   53.965 ? 1127 HOH B O   1 
HETATM 9595 O  O   . HOH H 4 .   ? -14.489 -33.393 5.228   1   37.63  ? 1128 HOH B O   1 
HETATM 9596 O  O   . HOH H 4 .   ? -12.541 -26.652 -10.105 1   38.812 ? 1129 HOH B O   1 
HETATM 9597 O  O   . HOH H 4 .   ? -4.489  10.823  13.134  1   22.685 ? 1130 HOH B O   1 
HETATM 9598 O  O   . HOH H 4 .   ? -40.138 -23.431 11.572  1   31.377 ? 1131 HOH B O   1 
HETATM 9599 O  O   . HOH H 4 .   ? 1.773   8.955   22.229  1   36.147 ? 1132 HOH B O   1 
HETATM 9600 O  O   . HOH H 4 .   ? -13.75  -9.6    2.78    1   19.407 ? 1133 HOH B O   1 
HETATM 9601 O  O   . HOH H 4 .   ? -10.3   -0.199  -15.317 1   53.326 ? 1134 HOH B O   1 
HETATM 9602 O  O   . HOH H 4 .   ? -30.083 -1.255  32.154  1   28.387 ? 1135 HOH B O   1 
HETATM 9603 O  O   . HOH H 4 .   ? -31.29  6.642   16.013  1   26.487 ? 1136 HOH B O   1 
HETATM 9604 O  O   . HOH H 4 .   ? -10.543 -4.534  1.679   1   34.185 ? 1137 HOH B O   1 
HETATM 9605 O  O   . HOH H 4 .   ? 3.315   12.05   12.831  1   39.212 ? 1138 HOH B O   1 
HETATM 9606 O  O   . HOH H 4 .   ? -9.787  -3.16   -2.256  1   29.518 ? 1139 HOH B O   1 
HETATM 9607 O  O   . HOH H 4 .   ? -19.657 -0.003  26.578  1   13.968 ? 1140 HOH B O   1 
HETATM 9608 O  O   . HOH H 4 .   ? -19.771 -17.265 38.668  1   34.617 ? 1141 HOH B O   1 
HETATM 9609 O  O   . HOH H 4 .   ? -4.959  -18.201 23.002  1   26.045 ? 1142 HOH B O   1 
HETATM 9610 O  O   . HOH H 4 .   ? -28.588 -21.401 -21.432 1   43.108 ? 1143 HOH B O   1 
HETATM 9611 O  O   . HOH H 4 .   ? -17.263 5.703   35.102  1   27.775 ? 1144 HOH B O   1 
HETATM 9612 O  O   . HOH H 4 .   ? -29.283 -27.242 17.953  1   40.04  ? 1145 HOH B O   1 
HETATM 9613 O  O   . HOH H 4 .   ? 17.124  15.849  22.758  1   43.435 ? 1146 HOH B O   1 
HETATM 9614 O  O   . HOH H 4 .   ? 12.883  -20.814 8.383   1   46.356 ? 1147 HOH B O   1 
HETATM 9615 O  O   . HOH H 4 .   ? -39.536 0.071   -11.244 1   32     ? 1148 HOH B O   1 
HETATM 9616 O  O   . HOH H 4 .   ? -46.425 -6.707  14.733  1   39.801 ? 1149 HOH B O   1 
HETATM 9617 O  O   . HOH H 4 .   ? -17.919 -14.91  31.414  1   44.788 ? 1150 HOH B O   1 
HETATM 9618 O  O   . HOH H 4 .   ? -19.985 10.94   9.073   1   37.799 ? 1151 HOH B O   1 
HETATM 9619 O  O   . HOH H 4 .   ? -16.661 -20.685 39.085  1   36.406 ? 1152 HOH B O   1 
HETATM 9620 O  O   . HOH H 4 .   ? -16.151 10.941  1.112   1   35.883 ? 1153 HOH B O   1 
HETATM 9621 O  O   . HOH H 4 .   ? -7.774  -4.557  -1.439  1   33.32  ? 1154 HOH B O   1 
HETATM 9622 O  O   . HOH H 4 .   ? -7.845  -3.182  -12.893 1   39.7   ? 1155 HOH B O   1 
HETATM 9623 O  O   . HOH H 4 .   ? -25.33  10.59   9.713   1   30.926 ? 1156 HOH B O   1 
HETATM 9624 O  O   . HOH H 4 .   ? -27.599 8.337   -2.298  1   40.149 ? 1157 HOH B O   1 
HETATM 9625 O  O   . HOH H 4 .   ? -20.25  -22.018 21.386  1   34.491 ? 1158 HOH B O   1 
HETATM 9626 O  O   . HOH H 4 .   ? -5.885  -8.107  24.987  1   19.46  ? 1159 HOH B O   1 
HETATM 9627 O  O   . HOH H 4 .   ? -15.243 -23.829 -13.374 1   41.667 ? 1160 HOH B O   1 
HETATM 9628 O  O   . HOH H 4 .   ? -1.916  8.562   19.059  1   35.892 ? 1161 HOH B O   1 
HETATM 9629 O  O   . HOH H 4 .   ? -6.611  -18.099 25.088  1   48.049 ? 1162 HOH B O   1 
HETATM 9630 O  O   . HOH H 4 .   ? -5.398  13.188  4.852   1   43.712 ? 1163 HOH B O   1 
HETATM 9631 O  O   . HOH H 4 .   ? -37.922 -33.496 13.2    1   34.287 ? 1164 HOH B O   1 
HETATM 9632 O  O   . HOH H 4 .   ? -16.9   -3.881  -14.552 1   40.53  ? 1165 HOH B O   1 
HETATM 9633 O  O   . HOH H 4 .   ? -40.386 -13.442 26.75   1   51.027 ? 1166 HOH B O   1 
HETATM 9634 O  O   . HOH H 4 .   ? 2.32    -4.428  -3.558  1   43.789 ? 1167 HOH B O   1 
HETATM 9635 O  O   . HOH H 4 .   ? -7.109  -14.855 30.379  1   25.428 ? 1168 HOH B O   1 
HETATM 9636 O  O   . HOH H 4 .   ? -23.675 4.656   -14.325 1   41.425 ? 1169 HOH B O   1 
HETATM 9637 O  O   . HOH H 4 .   ? -46.515 -12.725 11.969  1   39.947 ? 1170 HOH B O   1 
HETATM 9638 O  O   . HOH H 4 .   ? -1.751  -35.507 11.782  1   56.602 ? 1171 HOH B O   1 
HETATM 9639 O  O   . HOH H 4 .   ? -38.051 3.789   -2.146  1   47.261 ? 1172 HOH B O   1 
HETATM 9640 O  O   . HOH H 4 .   ? 2.841   -14.285 26.413  1   27.998 ? 1173 HOH B O   1 
HETATM 9641 O  O   . HOH H 4 .   ? 29.929  13.251  38.694  1   26.855 ? 1174 HOH B O   1 
HETATM 9642 O  O   . HOH H 4 .   ? -25.159 8.308   27.799  1   22.648 ? 1175 HOH B O   1 
HETATM 9643 O  O   . HOH H 4 .   ? -14.138 9.454   -8.329  1   35.732 ? 1176 HOH B O   1 
HETATM 9644 O  O   . HOH H 4 .   ? -41.249 -14.828 20.808  1   41.745 ? 1177 HOH B O   1 
HETATM 9645 O  O   . HOH H 4 .   ? 8.625   10.23   6.433   1   49.731 ? 1178 HOH B O   1 
HETATM 9646 O  O   . HOH H 4 .   ? 7.593   1.104   0.743   1   43.576 ? 1179 HOH B O   1 
HETATM 9647 O  O   . HOH H 4 .   ? -21.347 -24.8   -16.456 1   45.854 ? 1180 HOH B O   1 
HETATM 9648 O  O   . HOH H 4 .   ? -0.459  16.344  6.153   1   47.055 ? 1181 HOH B O   1 
HETATM 9649 O  O   . HOH H 4 .   ? -0.596  16.980  10.670  1   42.904 ? 1182 HOH B O   1 
HETATM 9650 O  O   . HOH H 4 .   ? 8.833   19.907  22.667  1   42.216 ? 1183 HOH B O   1 
HETATM 9651 O  O   . HOH H 4 .   ? -22.546 12.723  9.62    1   45.333 ? 1184 HOH B O   1 
HETATM 9652 O  O   . HOH H 4 .   ? -33.408 7.961   27.525  1   55.463 ? 1185 HOH B O   1 
HETATM 9653 O  O   . HOH H 4 .   ? -9.159  -0.632  -2.762  1   34.278 ? 1186 HOH B O   1 
HETATM 9654 O  O   . HOH H 4 .   ? -15.429 -11.602 3.388   1   18.641 ? 1187 HOH B O   1 
HETATM 9655 O  O   . HOH H 4 .   ? -2.663  -6.976  -10.849 1   57.437 ? 1188 HOH B O   1 
HETATM 9656 O  O   . HOH H 4 .   ? 29.645  17.891  37.881  1   49.474 ? 1189 HOH B O   1 
HETATM 9657 O  O   . HOH H 4 .   ? -4.845  -31.67  3.047   1   49.414 ? 1190 HOH B O   1 
HETATM 9658 O  O   . HOH H 4 .   ? 6.77    3.364   11.276  1   27.992 ? 1191 HOH B O   1 
HETATM 9659 O  O   . HOH H 4 .   ? -30.726 -10.761 -15.852 1   34.81  ? 1192 HOH B O   1 
HETATM 9660 O  O   . HOH H 4 .   ? -25.154 7.546   31.698  1   30.225 ? 1193 HOH B O   1 
HETATM 9661 O  O   . HOH H 4 .   ? -5.214  8.615   0.814   1   39.571 ? 1194 HOH B O   1 
HETATM 9662 O  O   . HOH H 4 .   ? 11.318  -1.83   1.177   1   47.352 ? 1195 HOH B O   1 
HETATM 9663 O  O   . HOH H 4 .   ? -34.166 -19.443 20.735  1   38.742 ? 1196 HOH B O   1 
HETATM 9664 O  O   . HOH H 4 .   ? -9.031  9.854   -0.971  1   36.671 ? 1197 HOH B O   1 
HETATM 9665 O  O   . HOH H 4 .   ? -7.52   4.017   23.332  1   21.402 ? 1198 HOH B O   1 
HETATM 9666 O  O   . HOH H 4 .   ? 2.216   -26.661 -0.782  1   44.145 ? 1199 HOH B O   1 
HETATM 9667 O  O   . HOH H 4 .   ? 5.489   2.528   -0.735  1   53.969 ? 1200 HOH B O   1 
HETATM 9668 O  O   . HOH H 4 .   ? -28.671 -10.614 25.514  1   22.914 ? 1201 HOH B O   1 
HETATM 9669 O  O   . HOH H 4 .   ? 23.56   19.97   39.695  1   24.228 ? 1202 HOH B O   1 
HETATM 9670 O  O   . HOH H 4 .   ? 18.422  20.982  38.709  1   22.024 ? 1203 HOH B O   1 
HETATM 9671 O  O   . HOH H 4 .   ? 13.929  -16.029 10.031  1   50.784 ? 1204 HOH B O   1 
HETATM 9672 O  O   . HOH H 4 .   ? -35.556 -18.768 18.558  1   26.835 ? 1205 HOH B O   1 
HETATM 9673 O  O   . HOH H 4 .   ? -26.766 -33.018 8.713   1   32.157 ? 1206 HOH B O   1 
HETATM 9674 O  O   . HOH H 4 .   ? -39.08  -14.644 -9.022  1   41.043 ? 1207 HOH B O   1 
HETATM 9675 O  O   . HOH H 4 .   ? -11.074 0.323   -4.509  1   40.28  ? 1208 HOH B O   1 
HETATM 9676 O  O   . HOH H 4 .   ? -32.686 6.14    30.808  1   37.439 ? 1209 HOH B O   1 
HETATM 9677 O  O   . HOH H 4 .   ? -44.227 -31.056 16.455  1   39.811 ? 1210 HOH B O   1 
HETATM 9678 O  O   . HOH H 4 .   ? 13.509  19.311  20.282  1   47.864 ? 1211 HOH B O   1 
HETATM 9679 O  O   . HOH H 4 .   ? -15.295 -22.422 38.139  1   43.195 ? 1212 HOH B O   1 
HETATM 9680 O  O   . HOH H 4 .   ? -28.66  -7.27   -17.478 1   41.173 ? 1213 HOH B O   1 
HETATM 9681 O  O   . HOH H 4 .   ? -21.523 5.398   -12.819 1   36.054 ? 1214 HOH B O   1 
HETATM 9682 O  O   . HOH H 4 .   ? -7.245  7.829   -0.736  1   42.97  ? 1215 HOH B O   1 
HETATM 9683 O  O   . HOH H 4 .   ? -6.522  -4.119  -4.233  1   35.048 ? 1216 HOH B O   1 
HETATM 9684 O  O   . HOH H 4 .   ? -37.075 4.535   5.591   1   54.984 ? 1217 HOH B O   1 
HETATM 9685 O  O   . HOH H 4 .   ? -8.851  3.378   -1.589  1   20.64  ? 1218 HOH B O   1 
HETATM 9686 O  O   . HOH H 4 .   ? 15.221  14.516  14.455  1   53.024 ? 1219 HOH B O   1 
HETATM 9687 O  O   . HOH H 4 .   ? -11.6   10.985  -6.744  1   59.661 ? 1220 HOH B O   1 
HETATM 9688 O  O   . HOH H 4 .   ? -2.605  -31.983 -1.545  1   35.549 ? 1221 HOH B O   1 
HETATM 9689 O  O   . HOH H 4 .   ? -38.888 -23.025 -4.149  1   55.228 ? 1222 HOH B O   1 
HETATM 9690 O  O   . HOH H 4 .   ? -23.138 -22.192 17.368  1   44.598 ? 1223 HOH B O   1 
HETATM 9691 O  O   . HOH H 4 .   ? -6.733  -30.671 -4.021  1   51.734 ? 1224 HOH B O   1 
HETATM 9692 O  O   . HOH H 4 .   ? -26.108 -13.772 -20.423 1   37.894 ? 1225 HOH B O   1 
HETATM 9693 O  O   . HOH H 4 .   ? -9.215  -28.003 15.919  1   39.38  ? 1226 HOH B O   1 
HETATM 9694 O  O   . HOH H 4 .   ? -3.696  -17.133 -12.735 1   48.892 ? 1227 HOH B O   1 
HETATM 9695 O  O   . HOH H 4 .   ? -39.6   -21.091 -5.831  1   56.284 ? 1228 HOH B O   1 
HETATM 9696 O  O   . HOH H 4 .   ? -2.21   10.654  14.479  1   31.29  ? 1229 HOH B O   1 
HETATM 9697 O  O   . HOH H 4 .   ? -42.588 -4.233  6.599   1   33.248 ? 1230 HOH B O   1 
HETATM 9698 O  O   . HOH H 4 .   ? -4.303  12.462  10.791  1   40.448 ? 1231 HOH B O   1 
HETATM 9699 O  O   . HOH H 4 .   ? -17.783 -24.589 -13.805 1   37.433 ? 1232 HOH B O   1 
HETATM 9700 O  O   . HOH H 4 .   ? -5.404  12.349  15.123  1   30.824 ? 1233 HOH B O   1 
HETATM 9701 O  O   . HOH H 4 .   ? 24.767  22.64   32.515  1   36.576 ? 1234 HOH B O   1 
HETATM 9702 O  O   . HOH H 4 .   ? -25.063 -8.034  -18.635 1   42.792 ? 1235 HOH B O   1 
HETATM 9703 O  O   . HOH H 4 .   ? 8.76    -4.123  -6.92   1   53.621 ? 1236 HOH B O   1 
HETATM 9704 O  O   . HOH H 4 .   ? -9.238  1.779   -8.45   1   42.859 ? 1237 HOH B O   1 
HETATM 9705 O  O   . HOH H 4 .   ? -15.365 13.71   18.988  1   32.131 ? 1238 HOH B O   1 
HETATM 9706 O  O   . HOH H 4 .   ? 5.011   -19.66  -6.275  1   38.658 ? 1239 HOH B O   1 
HETATM 9707 O  O   . HOH H 4 .   ? 12.683  -22.257 10.491  1   42.279 ? 1240 HOH B O   1 
HETATM 9708 O  O   . HOH H 4 .   ? -43.021 -2.367  10.415  1   25.179 ? 1241 HOH B O   1 
HETATM 9709 O  O   . HOH H 4 .   ? -36.831 -17.186 -5.917  1   37.068 ? 1242 HOH B O   1 
HETATM 9710 O  O   . HOH H 4 .   ? -11.52  -24.59  46.385  1   35.586 ? 1243 HOH B O   1 
HETATM 9711 O  O   . HOH H 4 .   ? -31.574 5.447   32.702  1   34.569 ? 1244 HOH B O   1 
HETATM 9712 O  O   . HOH H 4 .   ? -20.405 11.219  33.417  1   48.293 ? 1245 HOH B O   1 
HETATM 9713 O  O   . HOH H 4 .   ? -1.654  -10.568 -13.504 1   38.71  ? 1246 HOH B O   1 
HETATM 9714 O  O   . HOH H 4 .   ? -13.784 -7.661  -0.151  1   22.605 ? 1247 HOH B O   1 
HETATM 9715 O  O   . HOH H 4 .   ? -25.8   -33.181 4.296   1   37.256 ? 1248 HOH B O   1 
HETATM 9716 O  O   . HOH H 4 .   ? -33.126 -29.992 0.841   1   46.511 ? 1249 HOH B O   1 
HETATM 9717 O  O   . HOH H 4 .   ? -47.592 -8.435  16.512  1   41.249 ? 1250 HOH B O   1 
HETATM 9718 O  O   . HOH H 4 .   ? -11.478 -22.045 21.795  1   49.277 ? 1251 HOH B O   1 
HETATM 9719 O  O   . HOH H 4 .   ? -24.478 -22.054 19.546  1   43.538 ? 1252 HOH B O   1 
HETATM 9720 O  O   . HOH H 4 .   ? -30.159 -22.392 -13.828 1   28.818 ? 1253 HOH B O   1 
HETATM 9721 O  O   . HOH H 4 .   ? -12.482 -22.266 37.132  1   40.666 ? 1254 HOH B O   1 
HETATM 9722 O  O   . HOH H 4 .   ? -43.311 -6.645  9.359   1   33.098 ? 1255 HOH B O   1 
HETATM 9723 O  O   . HOH H 4 .   ? -13.591 -10.24  -0.159  1   27.278 ? 1256 HOH B O   1 
HETATM 9724 O  O   . HOH H 4 .   ? -6.876  11.555  18.978  1   32.408 ? 1257 HOH B O   1 
HETATM 9725 O  O   . HOH H 4 .   ? -6.55   14.037  10.49   1   53.534 ? 1258 HOH B O   1 
HETATM 9726 O  O   . HOH H 4 .   ? 12.596  -15.268 5.843   1   34.533 ? 1259 HOH B O   1 
HETATM 9727 O  O   . HOH H 4 .   ? 8.867   5.329   14.556  1   29.108 ? 1260 HOH B O   1 
HETATM 9728 O  O   . HOH H 4 .   ? -15.302 -16.804 37.017  1   31.311 ? 1261 HOH B O   1 
HETATM 9729 O  O   . HOH H 4 .   ? -38.537 -33.164 10.221  1   39.088 ? 1262 HOH B O   1 
HETATM 9730 O  O   . HOH H 4 .   ? -9.42   12.349  15.349  1   36.771 ? 1263 HOH B O   1 
HETATM 9731 O  O   . HOH H 4 .   ? -34.150 -2.044  -19.624 1   26.276 ? 1264 HOH B O   1 
HETATM 9732 O  O   . HOH H 4 .   ? -17.251 -17.532 35.205  1   43.537 ? 1265 HOH B O   1 
HETATM 9733 O  O   . HOH H 4 .   ? -8.644  11.557  1.635   1   44.112 ? 1266 HOH B O   1 
HETATM 9734 O  O   . HOH H 4 .   ? -26.207 -27.818 15.77   1   34.844 ? 1267 HOH B O   1 
HETATM 9735 O  O   . HOH H 4 .   ? 9.707   -13.036 3.386   1   45.841 ? 1268 HOH B O   1 
HETATM 9736 O  O   . HOH H 4 .   ? -23.959 -19.839 20.877  1   39.087 ? 1269 HOH B O   1 
HETATM 9737 O  O   . HOH H 4 .   ? -18.58  3.257   -14.489 1   47.127 ? 1270 HOH B O   1 
HETATM 9738 O  O   . HOH H 4 .   ? 8.985   -19.552 2.729   1   31.126 ? 1271 HOH B O   1 
HETATM 9739 O  O   . HOH H 4 .   ? -4.601  -6.862  -13.075 1   35.227 ? 1272 HOH B O   1 
HETATM 9740 O  O   . HOH H 4 .   ? -27.788 -25.838 -15.952 1   40.288 ? 1273 HOH B O   1 
HETATM 9741 O  O   . HOH H 4 .   ? 11.213  -16.767 20.778  1   42.74  ? 1274 HOH B O   1 
HETATM 9742 O  O   . HOH H 4 .   ? -7.686  11.988  5.823   1   30.244 ? 1275 HOH B O   1 
HETATM 9743 O  O   . HOH H 4 .   ? -7.412  10.014  7.677   1   25.702 ? 1276 HOH B O   1 
HETATM 9744 O  O   . HOH H 4 .   ? -17.238 15.538  15.674  1   32.304 ? 1277 HOH B O   1 
HETATM 9745 O  O   . HOH H 4 .   ? 4.145   2.772   10.967  1   20.756 ? 1278 HOH B O   1 
HETATM 9746 O  O   . HOH H 4 .   ? 9.532   -8.349  -6.181  1   40.701 ? 1279 HOH B O   1 
HETATM 9747 O  O   . HOH H 4 .   ? -9.838  3.819   -6.567  1   41.908 ? 1280 HOH B O   1 
HETATM 9748 O  O   . HOH H 4 .   ? -4.312  12.702  2.523   1   34.824 ? 1281 HOH B O   1 
HETATM 9749 O  O   . HOH H 4 .   ? -7.265  -1.158  0.038   1   33.412 ? 1282 HOH B O   1 
HETATM 9750 O  O   . HOH H 4 .   ? -26.416 -23.61  -15.826 1   29.412 ? 1283 HOH B O   1 
HETATM 9751 O  O   . HOH H 4 .   ? -22.206 10.075  -12.082 1   53.152 ? 1284 HOH B O   1 
HETATM 9752 O  O   . HOH H 4 .   ? -23.754 -26.831 -13.587 1   30.71  ? 1285 HOH B O   1 
HETATM 9753 O  O   . HOH H 4 .   ? -36.346 -16.683 22.657  1   30.007 ? 1286 HOH B O   1 
HETATM 9754 O  O   . HOH H 4 .   ? -39.835 -20.607 -1.149  1   53.53  ? 1287 HOH B O   1 
HETATM 9755 O  O   . HOH H 4 .   ? -15.982 -19.89  47.807  1   45.689 ? 1288 HOH B O   1 
HETATM 9756 O  O   . HOH H 4 .   ? 18.159  23.245  37.273  1   40.53  ? 1289 HOH B O   1 
HETATM 9757 O  O   . HOH H 4 .   ? -4.126  -5.268  -3.45   1   33.92  ? 1290 HOH B O   1 
HETATM 9758 O  O   . HOH H 4 .   ? -39.711 -16.866 20.046  1   28.484 ? 1291 HOH B O   1 
HETATM 9759 O  O   . HOH H 4 .   ? -34.178 -7.395  34.988  1   48.37  ? 1292 HOH B O   1 
HETATM 9760 O  O   . HOH H 4 .   ? -20.065 -21.753 25.841  1   38.774 ? 1293 HOH B O   1 
HETATM 9761 O  O   . HOH H 4 .   ? -29.235 -13.281 35.693  1   54.053 ? 1294 HOH B O   1 
HETATM 9762 O  O   . HOH H 4 .   ? -10.511 12.603  9.166   1   29.21  ? 1295 HOH B O   1 
HETATM 9763 O  O   . HOH H 4 .   ? -2.206  -3.693  -4.94   1   43.28  ? 1296 HOH B O   1 
HETATM 9764 O  O   . HOH H 4 .   ? -28.185 5.87    30.04   1   25.694 ? 1297 HOH B O   1 
HETATM 9765 O  O   . HOH H 4 .   ? 17.843  22.744  30.43   1   44.193 ? 1298 HOH B O   1 
HETATM 9766 O  O   . HOH H 4 .   ? -43.619 -15.79  19.272  1   53.932 ? 1299 HOH B O   1 
HETATM 9767 O  O   . HOH H 4 .   ? -5.386  15.695  4.316   1   45.782 ? 1300 HOH B O   1 
HETATM 9768 O  O   . HOH H 4 .   ? -7.774  -8.951  -14.774 1   30.076 ? 1301 HOH B O   1 
HETATM 9769 O  O   . HOH H 4 .   ? -34.641 -4.583  -19.218 1   33.642 ? 1302 HOH B O   1 
HETATM 9770 O  O   . HOH H 4 .   ? -38.714 -20.295 -3.593  1   51.852 ? 1303 HOH B O   1 
HETATM 9771 O  O   . HOH H 4 .   ? -12.421 -23.034 48.682  1   31.277 ? 1304 HOH B O   1 
HETATM 9772 O  O   . HOH H 4 .   ? -17.096 12.465  31.947  1   40.914 ? 1305 HOH B O   1 
HETATM 9773 O  O   . HOH H 4 .   ? -11.742 13.658  16.203  1   27.797 ? 1306 HOH B O   1 
HETATM 9774 O  O   . HOH H 4 .   ? -10.548 -24.567 20.671  1   54.183 ? 1307 HOH B O   1 
HETATM 9775 O  O   . HOH H 4 .   ? -39.168 -16.065 -6.702  1   49.915 ? 1308 HOH B O   1 
HETATM 9776 O  O   . HOH H 4 .   ? -13.261 -8.416  -17.138 1   41.591 ? 1309 HOH B O   1 
HETATM 9777 O  O   . HOH H 4 .   ? -10.231 -5.749  -15.513 1   42.107 ? 1310 HOH B O   1 
HETATM 9778 O  O   . HOH H 4 .   ? -22.412 -20.488 25.487  1   39.216 ? 1311 HOH B O   1 
HETATM 9779 O  O   . HOH H 4 .   ? -3.695  9.684   -3.447  1   64.385 ? 1312 HOH B O   1 
HETATM 9780 O  O   . HOH H 4 .   ? -10.761 13.91   11.329  1   42.946 ? 1313 HOH B O   1 
HETATM 9781 O  O   . HOH H 4 .   ? -7.037  0.558   -4.124  1   41.047 ? 1314 HOH B O   1 
HETATM 9782 O  O   . HOH H 4 .   ? -7.376  3.585   -3.996  1   37.408 ? 1315 HOH B O   1 
HETATM 9783 O  O   . HOH H 4 .   ? -32.396 9.405   -1.749  1   47.611 ? 1316 HOH B O   1 
HETATM 9784 O  O   . HOH H 4 .   ? 37.485  9.125   41.43   1   38.118 ? 1317 HOH B O   1 
HETATM 9785 O  O   . HOH H 4 .   ? -40.163 -15.989 -4.505  1   45.056 ? 1318 HOH B O   1 
HETATM 9786 O  O   . HOH H 4 .   ? -5.866  -1.373  -2.683  1   31.722 ? 1319 HOH B O   1 
HETATM 9787 O  O   . HOH H 4 .   ? -28.904 4.962   32.331  1   27.734 ? 1320 HOH B O   1 
HETATM 9788 O  O   . HOH H 4 .   ? -9.156  14.1    7.421   1   38.746 ? 1321 HOH B O   1 
HETATM 9789 O  O   . HOH H 4 .   ? -4.175  -9.294  -14.981 1   49.627 ? 1322 HOH B O   1 
# 
