data_9G2J
# 
_entry.id   9G2J 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9G2J         pdb_00009g2j 10.2210/pdb9g2j/pdb 
WWPDB D_1292140181 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-18 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9G2J 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              Thomas.Barends@mr.mpg.de 
_pdbx_contact_author.name_first         Thomas 
_pdbx_contact_author.name_last          Barends 
_pdbx_contact_author.name_mi            R.M. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9488-3005 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Doak, R.B.'      1 ? 
'Shoeman, R.L.'   2 ? 
'Gorel, A.'       3 ? 
'Barends, T.R.M.' 4 ? 
'Schlichting, I.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   DK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Appl.Crystallogr. 
_citation.journal_id_ASTM           JACGAR 
_citation.journal_id_CSD            0228 
_citation.journal_id_ISSN           0021-8898 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            57 
_citation.language                  ? 
_citation.page_first                1725 
_citation.page_last                 1732 
_citation.title                     
'Sheet-on-sheet fixed target data collection devices for serial crystallography at synchrotron and XFEL sources.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S1600576724008914 
_citation.pdbx_database_id_PubMed   39628875 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Doak, R.B.'      1 ?                   
primary 'Shoeman, R.L.'   2 ?                   
primary 'Gorel, A.'       3 ?                   
primary 'Nizinski, S.'    4 0000-0001-7608-7702 
primary 'Barends, T.R.M.' 5 0000-0002-9488-3005 
primary 'Schlichting, I.' 6 0000-0002-0936-7496 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat 'Thaumatin I'        22243.119 1   ? ? ? ? 
2 non-polymer syn 'L(+)-TARTARIC ACID' 150.087   1   ? ? ? ? 
3 water       nat water                18.015    128 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        Thaumatin-1 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTKGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRF
GRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCT
TGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTKGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRF
GRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCT
TGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'L(+)-TARTARIC ACID' TLA 
3 water                HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   THR n 
1 3   PHE n 
1 4   GLU n 
1 5   ILE n 
1 6   VAL n 
1 7   ASN n 
1 8   ARG n 
1 9   CYS n 
1 10  SER n 
1 11  TYR n 
1 12  THR n 
1 13  VAL n 
1 14  TRP n 
1 15  ALA n 
1 16  ALA n 
1 17  ALA n 
1 18  SER n 
1 19  LYS n 
1 20  GLY n 
1 21  ASP n 
1 22  ALA n 
1 23  ALA n 
1 24  LEU n 
1 25  ASP n 
1 26  ALA n 
1 27  GLY n 
1 28  GLY n 
1 29  ARG n 
1 30  GLN n 
1 31  LEU n 
1 32  ASN n 
1 33  SER n 
1 34  GLY n 
1 35  GLU n 
1 36  SER n 
1 37  TRP n 
1 38  THR n 
1 39  ILE n 
1 40  ASN n 
1 41  VAL n 
1 42  GLU n 
1 43  PRO n 
1 44  GLY n 
1 45  THR n 
1 46  LYS n 
1 47  GLY n 
1 48  GLY n 
1 49  LYS n 
1 50  ILE n 
1 51  TRP n 
1 52  ALA n 
1 53  ARG n 
1 54  THR n 
1 55  ASP n 
1 56  CYS n 
1 57  TYR n 
1 58  PHE n 
1 59  ASP n 
1 60  ASP n 
1 61  SER n 
1 62  GLY n 
1 63  SER n 
1 64  GLY n 
1 65  ILE n 
1 66  CYS n 
1 67  LYS n 
1 68  THR n 
1 69  GLY n 
1 70  ASP n 
1 71  CYS n 
1 72  GLY n 
1 73  GLY n 
1 74  LEU n 
1 75  LEU n 
1 76  ARG n 
1 77  CYS n 
1 78  LYS n 
1 79  ARG n 
1 80  PHE n 
1 81  GLY n 
1 82  ARG n 
1 83  PRO n 
1 84  PRO n 
1 85  THR n 
1 86  THR n 
1 87  LEU n 
1 88  ALA n 
1 89  GLU n 
1 90  PHE n 
1 91  SER n 
1 92  LEU n 
1 93  ASN n 
1 94  GLN n 
1 95  TYR n 
1 96  GLY n 
1 97  LYS n 
1 98  ASP n 
1 99  TYR n 
1 100 ILE n 
1 101 ASP n 
1 102 ILE n 
1 103 SER n 
1 104 ASN n 
1 105 ILE n 
1 106 LYS n 
1 107 GLY n 
1 108 PHE n 
1 109 ASN n 
1 110 VAL n 
1 111 PRO n 
1 112 MET n 
1 113 ASP n 
1 114 PHE n 
1 115 SER n 
1 116 PRO n 
1 117 THR n 
1 118 THR n 
1 119 ARG n 
1 120 GLY n 
1 121 CYS n 
1 122 ARG n 
1 123 GLY n 
1 124 VAL n 
1 125 ARG n 
1 126 CYS n 
1 127 ALA n 
1 128 ALA n 
1 129 ASP n 
1 130 ILE n 
1 131 VAL n 
1 132 GLY n 
1 133 GLN n 
1 134 CYS n 
1 135 PRO n 
1 136 ALA n 
1 137 LYS n 
1 138 LEU n 
1 139 LYS n 
1 140 ALA n 
1 141 PRO n 
1 142 GLY n 
1 143 GLY n 
1 144 GLY n 
1 145 CYS n 
1 146 ASN n 
1 147 ASP n 
1 148 ALA n 
1 149 CYS n 
1 150 THR n 
1 151 VAL n 
1 152 PHE n 
1 153 GLN n 
1 154 THR n 
1 155 SER n 
1 156 GLU n 
1 157 TYR n 
1 158 CYS n 
1 159 CYS n 
1 160 THR n 
1 161 THR n 
1 162 GLY n 
1 163 LYS n 
1 164 CYS n 
1 165 GLY n 
1 166 PRO n 
1 167 THR n 
1 168 GLU n 
1 169 TYR n 
1 170 SER n 
1 171 ARG n 
1 172 PHE n 
1 173 PHE n 
1 174 LYS n 
1 175 ARG n 
1 176 LEU n 
1 177 CYS n 
1 178 PRO n 
1 179 ASP n 
1 180 ALA n 
1 181 PHE n 
1 182 SER n 
1 183 TYR n 
1 184 VAL n 
1 185 LEU n 
1 186 ASP n 
1 187 LYS n 
1 188 PRO n 
1 189 THR n 
1 190 THR n 
1 191 VAL n 
1 192 THR n 
1 193 CYS n 
1 194 PRO n 
1 195 GLY n 
1 196 SER n 
1 197 SER n 
1 198 ASN n 
1 199 TYR n 
1 200 ARG n 
1 201 VAL n 
1 202 THR n 
1 203 PHE n 
1 204 CYS n 
1 205 PRO n 
1 206 THR n 
1 207 ALA n 
# 
_entity_src_nat.entity_id                  1 
_entity_src_nat.pdbx_src_id                1 
_entity_src_nat.pdbx_alt_source_flag       sample 
_entity_src_nat.pdbx_beg_seq_num           1 
_entity_src_nat.pdbx_end_seq_num           207 
_entity_src_nat.common_name                ? 
_entity_src_nat.pdbx_organism_scientific   'Thaumatococcus daniellii' 
_entity_src_nat.pdbx_ncbi_taxonomy_id      4621 
_entity_src_nat.genus                      ? 
_entity_src_nat.species                    ? 
_entity_src_nat.strain                     ? 
_entity_src_nat.tissue                     ? 
_entity_src_nat.tissue_fraction            ? 
_entity_src_nat.pdbx_secretion             ? 
_entity_src_nat.pdbx_fragment              ? 
_entity_src_nat.pdbx_variant               ? 
_entity_src_nat.pdbx_cell_line             ? 
_entity_src_nat.pdbx_atcc                  ? 
_entity_src_nat.pdbx_cellular_location     ? 
_entity_src_nat.pdbx_organ                 ? 
_entity_src_nat.pdbx_organelle             ? 
_entity_src_nat.pdbx_cell                  ? 
_entity_src_nat.pdbx_plasmid_name          ? 
_entity_src_nat.pdbx_plasmid_details       ? 
_entity_src_nat.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE              ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE             ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE           ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'      ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE             ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE            ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'      ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE              ? 'C2 H5 N O2'     75.067  
HOH non-polymer         . WATER                ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE           ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE              ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE               ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE           ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE        ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE              ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE               ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE            ? 'C4 H9 N O3'     119.119 
TLA non-polymer         . 'L(+)-TARTARIC ACID' ? 'C4 H6 O6'       150.087 
TRP 'L-peptide linking' y TRYPTOPHAN           ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE             ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE               ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   THR 2   2   2   THR THR A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   VAL 6   6   6   VAL VAL A . n 
A 1 7   ASN 7   7   7   ASN ASN A . n 
A 1 8   ARG 8   8   8   ARG ARG A . n 
A 1 9   CYS 9   9   9   CYS CYS A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  TYR 11  11  11  TYR TYR A . n 
A 1 12  THR 12  12  12  THR THR A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  TRP 14  14  14  TRP TRP A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  SER 18  18  18  SER SER A . n 
A 1 19  LYS 19  19  19  LYS LYS A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  ASP 21  21  21  ASP ASP A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  ASP 25  25  25  ASP ASP A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  GLY 28  28  28  GLY GLY A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  GLN 30  30  30  GLN GLN A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  ASN 32  32  32  ASN ASN A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  GLU 35  35  35  GLU GLU A . n 
A 1 36  SER 36  36  36  SER SER A . n 
A 1 37  TRP 37  37  37  TRP TRP A . n 
A 1 38  THR 38  38  38  THR THR A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  ASN 40  40  40  ASN ASN A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  GLU 42  42  42  GLU GLU A . n 
A 1 43  PRO 43  43  43  PRO PRO A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  TRP 51  51  51  TRP TRP A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ASP 55  55  55  ASP ASP A . n 
A 1 56  CYS 56  56  56  CYS CYS A . n 
A 1 57  TYR 57  57  57  TYR TYR A . n 
A 1 58  PHE 58  58  58  PHE PHE A . n 
A 1 59  ASP 59  59  59  ASP ASP A . n 
A 1 60  ASP 60  60  60  ASP ASP A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  SER 63  63  63  SER SER A . n 
A 1 64  GLY 64  64  64  GLY GLY A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  CYS 66  66  66  CYS CYS A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  CYS 71  71  71  CYS CYS A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  GLY 73  73  73  GLY GLY A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  CYS 77  77  77  CYS CYS A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  PHE 80  80  80  PHE PHE A . n 
A 1 81  GLY 81  81  81  GLY GLY A . n 
A 1 82  ARG 82  82  82  ARG ARG A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  PRO 84  84  84  PRO PRO A . n 
A 1 85  THR 85  85  85  THR THR A . n 
A 1 86  THR 86  86  86  THR THR A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  GLU 89  89  89  GLU GLU A . n 
A 1 90  PHE 90  90  90  PHE PHE A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  ASN 93  93  93  ASN ASN A . n 
A 1 94  GLN 94  94  94  GLN GLN A . n 
A 1 95  TYR 95  95  95  TYR TYR A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  ASP 98  98  98  ASP ASP A . n 
A 1 99  TYR 99  99  99  TYR TYR A . n 
A 1 100 ILE 100 100 100 ILE ILE A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 ILE 102 102 102 ILE ILE A . n 
A 1 103 SER 103 103 103 SER SER A . n 
A 1 104 ASN 104 104 104 ASN ASN A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 ASN 109 109 109 ASN ASN A . n 
A 1 110 VAL 110 110 110 VAL VAL A . n 
A 1 111 PRO 111 111 111 PRO PRO A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 PRO 116 116 116 PRO PRO A . n 
A 1 117 THR 117 117 117 THR THR A . n 
A 1 118 THR 118 118 118 THR THR A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 CYS 121 121 121 CYS CYS A . n 
A 1 122 ARG 122 122 122 ARG ARG A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 CYS 126 126 126 CYS CYS A . n 
A 1 127 ALA 127 127 127 ALA ALA A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 ASP 129 129 129 ASP ASP A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 GLY 132 132 132 GLY GLY A . n 
A 1 133 GLN 133 133 133 GLN GLN A . n 
A 1 134 CYS 134 134 134 CYS CYS A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 ALA 136 136 136 ALA ALA A . n 
A 1 137 LYS 137 137 137 LYS LYS A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 PRO 141 141 141 PRO PRO A . n 
A 1 142 GLY 142 142 142 GLY GLY A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 GLY 144 144 144 GLY GLY A . n 
A 1 145 CYS 145 145 145 CYS CYS A . n 
A 1 146 ASN 146 146 146 ASN ASN A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 CYS 149 149 149 CYS CYS A . n 
A 1 150 THR 150 150 150 THR THR A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 PHE 152 152 152 PHE PHE A . n 
A 1 153 GLN 153 153 153 GLN GLN A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 TYR 157 157 157 TYR TYR A . n 
A 1 158 CYS 158 158 158 CYS CYS A . n 
A 1 159 CYS 159 159 159 CYS CYS A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 THR 161 161 161 THR THR A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 LYS 163 163 163 LYS LYS A . n 
A 1 164 CYS 164 164 164 CYS CYS A . n 
A 1 165 GLY 165 165 165 GLY GLY A . n 
A 1 166 PRO 166 166 166 PRO PRO A . n 
A 1 167 THR 167 167 167 THR THR A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 TYR 169 169 169 TYR TYR A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 PHE 172 172 172 PHE PHE A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 LYS 174 174 174 LYS LYS A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 LEU 176 176 176 LEU LEU A . n 
A 1 177 CYS 177 177 177 CYS CYS A . n 
A 1 178 PRO 178 178 178 PRO PRO A . n 
A 1 179 ASP 179 179 179 ASP ASP A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 TYR 183 183 183 TYR TYR A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 LEU 185 185 185 LEU LEU A . n 
A 1 186 ASP 186 186 186 ASP ASP A . n 
A 1 187 LYS 187 187 187 LYS LYS A . n 
A 1 188 PRO 188 188 188 PRO PRO A . n 
A 1 189 THR 189 189 189 THR THR A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 CYS 193 193 193 CYS CYS A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 ASN 198 198 198 ASN ASN A . n 
A 1 199 TYR 199 199 199 TYR TYR A . n 
A 1 200 ARG 200 200 200 ARG ARG A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 PHE 203 203 203 PHE PHE A . n 
A 1 204 CYS 204 204 204 CYS CYS A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ALA 207 207 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 TLA 1   1001 1001 TLA TLA A . 
C 3 HOH 1   1101 100  HOH HOH A . 
C 3 HOH 2   1102 212  HOH HOH A . 
C 3 HOH 3   1103 108  HOH HOH A . 
C 3 HOH 4   1104 4    HOH HOH A . 
C 3 HOH 5   1105 2    HOH HOH A . 
C 3 HOH 6   1106 185  HOH HOH A . 
C 3 HOH 7   1107 88   HOH HOH A . 
C 3 HOH 8   1108 49   HOH HOH A . 
C 3 HOH 9   1109 4    HOH HOH A . 
C 3 HOH 10  1110 45   HOH HOH A . 
C 3 HOH 11  1111 120  HOH HOH A . 
C 3 HOH 12  1112 98   HOH HOH A . 
C 3 HOH 13  1113 1    HOH HOH A . 
C 3 HOH 14  1114 62   HOH HOH A . 
C 3 HOH 15  1115 49   HOH HOH A . 
C 3 HOH 16  1116 4    HOH HOH A . 
C 3 HOH 17  1117 9    HOH HOH A . 
C 3 HOH 18  1118 31   HOH HOH A . 
C 3 HOH 19  1119 26   HOH HOH A . 
C 3 HOH 20  1120 22   HOH HOH A . 
C 3 HOH 21  1121 76   HOH HOH A . 
C 3 HOH 22  1122 9    HOH HOH A . 
C 3 HOH 23  1123 32   HOH HOH A . 
C 3 HOH 24  1124 38   HOH HOH A . 
C 3 HOH 25  1125 206  HOH HOH A . 
C 3 HOH 26  1126 216  HOH HOH A . 
C 3 HOH 27  1127 72   HOH HOH A . 
C 3 HOH 28  1128 37   HOH HOH A . 
C 3 HOH 29  1129 28   HOH HOH A . 
C 3 HOH 30  1130 97   HOH HOH A . 
C 3 HOH 31  1131 118  HOH HOH A . 
C 3 HOH 32  1132 126  HOH HOH A . 
C 3 HOH 33  1133 68   HOH HOH A . 
C 3 HOH 34  1134 23   HOH HOH A . 
C 3 HOH 35  1135 24   HOH HOH A . 
C 3 HOH 36  1136 99   HOH HOH A . 
C 3 HOH 37  1137 213  HOH HOH A . 
C 3 HOH 38  1138 55   HOH HOH A . 
C 3 HOH 39  1139 153  HOH HOH A . 
C 3 HOH 40  1140 30   HOH HOH A . 
C 3 HOH 41  1141 133  HOH HOH A . 
C 3 HOH 42  1142 3    HOH HOH A . 
C 3 HOH 43  1143 50   HOH HOH A . 
C 3 HOH 44  1144 43   HOH HOH A . 
C 3 HOH 45  1145 80   HOH HOH A . 
C 3 HOH 46  1146 2    HOH HOH A . 
C 3 HOH 47  1147 12   HOH HOH A . 
C 3 HOH 48  1148 14   HOH HOH A . 
C 3 HOH 49  1149 8    HOH HOH A . 
C 3 HOH 50  1150 20   HOH HOH A . 
C 3 HOH 51  1151 41   HOH HOH A . 
C 3 HOH 52  1152 27   HOH HOH A . 
C 3 HOH 53  1153 7    HOH HOH A . 
C 3 HOH 54  1154 40   HOH HOH A . 
C 3 HOH 55  1155 143  HOH HOH A . 
C 3 HOH 56  1156 15   HOH HOH A . 
C 3 HOH 57  1157 35   HOH HOH A . 
C 3 HOH 58  1158 9    HOH HOH A . 
C 3 HOH 59  1159 110  HOH HOH A . 
C 3 HOH 60  1160 18   HOH HOH A . 
C 3 HOH 61  1161 14   HOH HOH A . 
C 3 HOH 62  1162 146  HOH HOH A . 
C 3 HOH 63  1163 48   HOH HOH A . 
C 3 HOH 64  1164 93   HOH HOH A . 
C 3 HOH 65  1165 16   HOH HOH A . 
C 3 HOH 66  1166 21   HOH HOH A . 
C 3 HOH 67  1167 39   HOH HOH A . 
C 3 HOH 68  1168 36   HOH HOH A . 
C 3 HOH 69  1169 84   HOH HOH A . 
C 3 HOH 70  1170 94   HOH HOH A . 
C 3 HOH 71  1171 19   HOH HOH A . 
C 3 HOH 72  1172 187  HOH HOH A . 
C 3 HOH 73  1173 200  HOH HOH A . 
C 3 HOH 74  1174 109  HOH HOH A . 
C 3 HOH 75  1175 24   HOH HOH A . 
C 3 HOH 76  1176 89   HOH HOH A . 
C 3 HOH 77  1177 75   HOH HOH A . 
C 3 HOH 78  1178 211  HOH HOH A . 
C 3 HOH 79  1179 66   HOH HOH A . 
C 3 HOH 80  1180 31   HOH HOH A . 
C 3 HOH 81  1181 58   HOH HOH A . 
C 3 HOH 82  1182 73   HOH HOH A . 
C 3 HOH 83  1183 29   HOH HOH A . 
C 3 HOH 84  1184 10   HOH HOH A . 
C 3 HOH 85  1185 60   HOH HOH A . 
C 3 HOH 86  1186 116  HOH HOH A . 
C 3 HOH 87  1187 3    HOH HOH A . 
C 3 HOH 88  1188 108  HOH HOH A . 
C 3 HOH 89  1189 1    HOH HOH A . 
C 3 HOH 90  1190 215  HOH HOH A . 
C 3 HOH 91  1191 170  HOH HOH A . 
C 3 HOH 92  1192 13   HOH HOH A . 
C 3 HOH 93  1193 57   HOH HOH A . 
C 3 HOH 94  1194 123  HOH HOH A . 
C 3 HOH 95  1195 28   HOH HOH A . 
C 3 HOH 96  1196 16   HOH HOH A . 
C 3 HOH 97  1197 18   HOH HOH A . 
C 3 HOH 98  1198 129  HOH HOH A . 
C 3 HOH 99  1199 46   HOH HOH A . 
C 3 HOH 100 1200 30   HOH HOH A . 
C 3 HOH 101 1201 20   HOH HOH A . 
C 3 HOH 102 1202 53   HOH HOH A . 
C 3 HOH 103 1203 2    HOH HOH A . 
C 3 HOH 104 1204 36   HOH HOH A . 
C 3 HOH 105 1205 43   HOH HOH A . 
C 3 HOH 106 1206 85   HOH HOH A . 
C 3 HOH 107 1207 100  HOH HOH A . 
C 3 HOH 108 1208 44   HOH HOH A . 
C 3 HOH 109 1209 214  HOH HOH A . 
C 3 HOH 110 1210 59   HOH HOH A . 
C 3 HOH 111 1211 122  HOH HOH A . 
C 3 HOH 112 1212 90   HOH HOH A . 
C 3 HOH 113 1213 101  HOH HOH A . 
C 3 HOH 114 1214 31   HOH HOH A . 
C 3 HOH 115 1215 67   HOH HOH A . 
C 3 HOH 116 1216 65   HOH HOH A . 
C 3 HOH 117 1217 165  HOH HOH A . 
C 3 HOH 118 1218 5    HOH HOH A . 
C 3 HOH 119 1219 87   HOH HOH A . 
C 3 HOH 120 1220 130  HOH HOH A . 
C 3 HOH 121 1221 91   HOH HOH A . 
C 3 HOH 122 1222 63   HOH HOH A . 
C 3 HOH 123 1223 164  HOH HOH A . 
C 3 HOH 124 1224 207  HOH HOH A . 
C 3 HOH 125 1225 51   HOH HOH A . 
C 3 HOH 126 1226 25   HOH HOH A . 
C 3 HOH 127 1227 105  HOH HOH A . 
C 3 HOH 128 1228 121  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0405 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9G2J 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     57.849 
_cell.length_a_esd                 ? 
_cell.length_b                     57.849 
_cell.length_b_esd                 ? 
_cell.length_c                     150.328 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9G2J 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9G2J 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.83 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          56.49 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.8 M NA, K TARTRATE, 0.1 M NA HEPES' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'PSI JUNGFRAU 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-01-01 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.073 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID29' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.073 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID29 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9G2J 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.69 
_reflns.d_resolution_low                               38 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     29237 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4475 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   0.067 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.69 
_reflns_shell.d_res_low                                     1.8 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1412 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  0.73 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.389 
_refine.aniso_B[1][2]                            0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            0.389 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.777 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               28.840 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.968 
_refine.correlation_coeff_Fo_to_Fc_free          0.966 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9G2J 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.690 
_refine.ls_d_res_low                             37.904 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     29237 
_refine.ls_number_reflns_R_free                  1412 
_refine.ls_number_reflns_R_work                  27825 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.934 
_refine.ls_percent_reflns_R_free                 4.829 
_refine.ls_R_factor_all                          0.158 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1688 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1576 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.078 
_refine.pdbx_overall_ESU_R_Free                  0.072 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.657 
_refine.overall_SU_ML                            0.053 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        1546 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         10 
_refine_hist.number_atoms_solvent             128 
_refine_hist.number_atoms_total               1684 
_refine_hist.d_res_high                       1.690 
_refine_hist.d_res_low                        37.904 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.013  0.011  1629 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  1460 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.751  1.656  2222 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.640  1.568  3388 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.946  5.000  217  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 8.124  5.000  12   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.898 10.000 251  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.535 10.000 67   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.089  0.200  238  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  1960 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  392  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200  300  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.200  0.200  1442 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.194  0.200  878  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.095  0.200  982  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.238  0.200  98   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.214  0.200  15   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.210  0.200  59   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.197  0.200  20   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 0.028  0.200  2    ? r_xyhbond_nbd_other            ? ? 
'X-RAY DIFFRACTION' ? 2.499  2.681  835  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.488  2.680  835  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.385  4.786  1045 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.388  4.788  1046 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 4.922  3.242  794  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.924  3.241  793  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 7.438  5.632  1171 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 7.439  5.631  1171 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 8.558  28.658 1877 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 8.523  28.307 1862 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.690 1.733  2139 . 68  1928 93.3146  . 0.278 . . 0.280 . . . . . 0.259 . 20 . 0.944 0.953 0.237 
'X-RAY DIFFRACTION' 1.733 1.781  2076 . 116 1960 100.0000 . 0.232 . . 0.231 . . . . . 0.204 . 20 . 0.964 0.954 0.246 
'X-RAY DIFFRACTION' 1.781 1.832  2026 . 97  1929 100.0000 . 0.200 . . 0.200 . . . . . 0.168 . 20 . 0.974 0.971 0.213 
'X-RAY DIFFRACTION' 1.832 1.889  1954 . 106 1848 100.0000 . 0.178 . . 0.177 . . . . . 0.144 . 20 . 0.980 0.975 0.197 
'X-RAY DIFFRACTION' 1.889 1.950  1929 . 90  1839 100.0000 . 0.153 . . 0.151 . . . . . 0.124 . 20 . 0.986 0.980 0.181 
'X-RAY DIFFRACTION' 1.950 2.019  1848 . 82  1766 100.0000 . 0.135 . . 0.136 . . . . . 0.114 . 20 . 0.989 0.990 0.133 
'X-RAY DIFFRACTION' 2.019 2.095  1799 . 83  1716 100.0000 . 0.137 . . 0.136 . . . . . 0.113 . 20 . 0.988 0.987 0.145 
'X-RAY DIFFRACTION' 2.095 2.180  1721 . 83  1470 90.2382  . 0.167 . . 0.167 . . . . . 0.142 . 20 . 0.970 0.958 0.171 
'X-RAY DIFFRACTION' 2.180 2.276  1674 . 73  1601 100.0000 . 0.419 . . 0.419 . . . . . 0.169 . 20 . 0.778 0.745 0.420 
'X-RAY DIFFRACTION' 2.276 2.387  1579 . 82  1497 100.0000 . 0.154 . . 0.154 . . . . . 0.135 . 20 . 0.983 0.982 0.164 
'X-RAY DIFFRACTION' 2.387 2.516  1549 . 68  1481 100.0000 . 0.141 . . 0.140 . . . . . 0.127 . 20 . 0.989 0.985 0.160 
'X-RAY DIFFRACTION' 2.516 2.668  1419 . 63  1356 100.0000 . 0.145 . . 0.145 . . . . . 0.132 . 20 . 0.988 0.986 0.155 
'X-RAY DIFFRACTION' 2.668 2.851  1368 . 80  1288 100.0000 . 0.143 . . 0.141 . . . . . 0.135 . 20 . 0.988 0.982 0.174 
'X-RAY DIFFRACTION' 2.851 3.078  1283 . 71  1212 100.0000 . 0.141 . . 0.139 . . . . . 0.138 . 20 . 0.987 0.981 0.170 
'X-RAY DIFFRACTION' 3.078 3.369  1188 . 60  1128 100.0000 . 0.131 . . 0.130 . . . . . 0.135 . 20 . 0.990 0.985 0.156 
'X-RAY DIFFRACTION' 3.369 3.763  1084 . 56  1028 100.0000 . 0.125 . . 0.124 . . . . . 0.133 . 20 . 0.991 0.992 0.141 
'X-RAY DIFFRACTION' 3.763 4.338  976  . 51  925  100.0000 . 0.111 . . 0.111 . . . . . 0.129 . 20 . 0.993 0.991 0.119 
'X-RAY DIFFRACTION' 4.338 5.296  832  . 39  793  100.0000 . 0.101 . . 0.100 . . . . . 0.120 . 20 . 0.995 0.994 0.111 
'X-RAY DIFFRACTION' 5.296 7.417  680  . 27  653  100.0000 . 0.141 . . 0.139 . . . . . 0.162 . 20 . 0.990 0.984 0.185 
'X-RAY DIFFRACTION' 7.417 37.904 424  . 17  407  100.0000 . 0.160 . . 0.159 . . . . . 0.185 . 20 . 0.978 0.972 0.185 
# 
_struct.entry_id                     9G2J 
_struct.title                        'Thaumatin structure determined using SoS chip at ID29 (serial crystallography)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9G2J 
_struct_keywords.text            'Thaumatin, PLANT PROTEIN' 
_struct_keywords.pdbx_keywords   'PLANT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    THM1_THADA 
_struct_ref.pdbx_db_accession          P02883 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRF
GRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCT
TGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA
;
_struct_ref.pdbx_align_begin           23 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9G2J 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 207 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P02883 
_struct_ref_seq.db_align_beg                  23 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  229 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       207 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9G2J 
_struct_ref_seq_dif.mon_id                       LYS 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      46 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P02883 
_struct_ref_seq_dif.db_mon_id                    ASN 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          68 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            46 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 190  ? 
1 MORE         1    ? 
1 'SSA (A^2)'  9480 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ASP A 129 ? CYS A 134 ? ASP A 129 CYS A 134 1 ? 6  
HELX_P HELX_P2 AA2 PRO A 135 ? LYS A 139 ? PRO A 135 LYS A 139 5 ? 5  
HELX_P HELX_P3 AA3 ASP A 147 ? GLN A 153 ? ASP A 147 GLN A 153 1 ? 7  
HELX_P HELX_P4 AA4 THR A 154 ? CYS A 159 ? THR A 154 CYS A 159 1 ? 6  
HELX_P HELX_P5 AA5 THR A 167 ? CYS A 177 ? THR A 167 CYS A 177 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 9   SG ? ? ? 1_555 A CYS 204 SG ? ? A CYS 9   A CYS 204 1_555 ? ? ? ? ? ? ? 1.996 ? ? 
disulf2 disulf ? ? A CYS 56  SG ? ? ? 1_555 A CYS 66  SG ? ? A CYS 56  A CYS 66  1_555 ? ? ? ? ? ? ? 2.021 ? ? 
disulf3 disulf ? ? A CYS 71  SG ? ? ? 1_555 A CYS 77  SG ? ? A CYS 71  A CYS 77  1_555 ? ? ? ? ? ? ? 2.018 ? ? 
disulf4 disulf ? ? A CYS 121 SG ? ? ? 1_555 A CYS 193 SG ? ? A CYS 121 A CYS 193 1_555 ? ? ? ? ? ? ? 2.041 ? ? 
disulf5 disulf ? ? A CYS 126 SG ? ? ? 1_555 A CYS 177 SG ? ? A CYS 126 A CYS 177 1_555 ? ? ? ? ? ? ? 2.017 ? ? 
disulf6 disulf ? ? A CYS 134 SG ? ? ? 1_555 A CYS 145 SG ? ? A CYS 134 A CYS 145 1_555 ? ? ? ? ? ? ? 2.019 ? ? 
disulf7 disulf ? ? A CYS 149 SG ? ? ? 1_555 A CYS 158 SG ? ? A CYS 149 A CYS 158 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf8 disulf ? ? A CYS 159 SG A ? ? 1_555 A CYS 164 SG ? ? A CYS 159 A CYS 164 1_555 ? ? ? ? ? ? ? 1.967 ? ? 
disulf9 disulf ? ? A CYS 159 SG B ? ? 1_555 A CYS 164 SG ? ? A CYS 159 A CYS 164 1_555 ? ? ? ? ? ? ? 1.888 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 9   ? CYS A 204 ? CYS A 9   ? 1_555 CYS A 204 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 56  ? CYS A 66  ? CYS A 56  ? 1_555 CYS A 66  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 71  ? CYS A 77  ? CYS A 71  ? 1_555 CYS A 77  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS A 121 ? CYS A 193 ? CYS A 121 ? 1_555 CYS A 193 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS A 126 ? CYS A 177 ? CYS A 126 ? 1_555 CYS A 177 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS A 134 ? CYS A 145 ? CYS A 134 ? 1_555 CYS A 145 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7 CYS A 149 ? CYS A 158 ? CYS A 149 ? 1_555 CYS A 158 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8 CYS A 159 A CYS A 164 ? CYS A 159 ? 1_555 CYS A 164 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9 CYS A 159 B CYS A 164 ? CYS A 159 ? 1_555 CYS A 164 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          PRO 
_struct_mon_prot_cis.label_seq_id           83 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           PRO 
_struct_mon_prot_cis.auth_seq_id            83 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    84 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     84 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       7.12 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 36  ? ASN A 40  ? SER A 36  ASN A 40  
AA1 2 THR A 2   ? ASN A 7   ? THR A 2   ASN A 7   
AA1 3 TYR A 199 ? PHE A 203 ? TYR A 199 PHE A 203 
AA1 4 MET A 112 ? PRO A 116 ? MET A 112 PRO A 116 
AA1 5 VAL A 124 ? CYS A 126 ? VAL A 124 CYS A 126 
AA2 1 ALA A 23  ? LEU A 31  ? ALA A 23  LEU A 31  
AA2 2 VAL A 13  ? SER A 18  ? VAL A 13  SER A 18  
AA2 3 GLY A 48  ? PHE A 58  ? GLY A 48  PHE A 58  
AA2 4 GLY A 64  ? THR A 68  ? GLY A 64  THR A 68  
AA3 1 ALA A 23  ? LEU A 31  ? ALA A 23  LEU A 31  
AA3 2 VAL A 13  ? SER A 18  ? VAL A 13  SER A 18  
AA3 3 GLY A 48  ? PHE A 58  ? GLY A 48  PHE A 58  
AA3 4 LEU A 87  ? GLN A 94  ? LEU A 87  GLN A 94  
AA3 5 LYS A 97  ? SER A 103 ? LYS A 97  SER A 103 
AA3 6 VAL A 191 ? PRO A 194 ? VAL A 191 PRO A 194 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TRP A 37  ? O TRP A 37  N ILE A 5   ? N ILE A 5   
AA1 2 3 N VAL A 6   ? N VAL A 6   O VAL A 201 ? O VAL A 201 
AA1 3 4 O ARG A 200 ? O ARG A 200 N SER A 115 ? N SER A 115 
AA1 4 5 N PHE A 114 ? N PHE A 114 O VAL A 124 ? O VAL A 124 
AA2 1 2 O LEU A 31  ? O LEU A 31  N VAL A 13  ? N VAL A 13  
AA2 2 3 N ALA A 16  ? N ALA A 16  O TRP A 51  ? O TRP A 51  
AA2 3 4 N TYR A 57  ? N TYR A 57  O ILE A 65  ? O ILE A 65  
AA3 1 2 O LEU A 31  ? O LEU A 31  N VAL A 13  ? N VAL A 13  
AA3 2 3 N ALA A 16  ? N ALA A 16  O TRP A 51  ? O TRP A 51  
AA3 3 4 N ILE A 50  ? N ILE A 50  O ALA A 88  ? O ALA A 88  
AA3 4 5 N GLN A 94  ? N GLN A 94  O LYS A 97  ? O LYS A 97  
AA3 5 6 N ASP A 98  ? N ASP A 98  O CYS A 193 ? O CYS A 193 
# 
_pdbx_entry_details.entry_id                   9G2J 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_1             168 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OE1 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            GLU 
_pdbx_validate_rmsd_bond.auth_seq_id_2             168 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.344 
_pdbx_validate_rmsd_bond.bond_target_value         1.252 
_pdbx_validate_rmsd_bond.bond_deviation            0.092 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.011 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             NE 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_1              29 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CZ 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_2              29 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             NH1 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ARG 
_pdbx_validate_rmsd_angle.auth_seq_id_3              29 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                117.03 
_pdbx_validate_rmsd_angle.angle_target_value         120.30 
_pdbx_validate_rmsd_angle.angle_deviation            -3.27 
_pdbx_validate_rmsd_angle.angle_standard_deviation   0.50 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 25 ? ? 55.82   -138.03 
2 1 CYS A 71 ? ? -112.36 68.23   
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     76 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.089 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     ALA 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      207 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    ALA 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     207 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HOH O    O N N 137 
HOH H1   H N N 138 
HOH H2   H N N 139 
ILE N    N N N 140 
ILE CA   C N S 141 
ILE C    C N N 142 
ILE O    O N N 143 
ILE CB   C N S 144 
ILE CG1  C N N 145 
ILE CG2  C N N 146 
ILE CD1  C N N 147 
ILE OXT  O N N 148 
ILE H    H N N 149 
ILE H2   H N N 150 
ILE HA   H N N 151 
ILE HB   H N N 152 
ILE HG12 H N N 153 
ILE HG13 H N N 154 
ILE HG21 H N N 155 
ILE HG22 H N N 156 
ILE HG23 H N N 157 
ILE HD11 H N N 158 
ILE HD12 H N N 159 
ILE HD13 H N N 160 
ILE HXT  H N N 161 
LEU N    N N N 162 
LEU CA   C N S 163 
LEU C    C N N 164 
LEU O    O N N 165 
LEU CB   C N N 166 
LEU CG   C N N 167 
LEU CD1  C N N 168 
LEU CD2  C N N 169 
LEU OXT  O N N 170 
LEU H    H N N 171 
LEU H2   H N N 172 
LEU HA   H N N 173 
LEU HB2  H N N 174 
LEU HB3  H N N 175 
LEU HG   H N N 176 
LEU HD11 H N N 177 
LEU HD12 H N N 178 
LEU HD13 H N N 179 
LEU HD21 H N N 180 
LEU HD22 H N N 181 
LEU HD23 H N N 182 
LEU HXT  H N N 183 
LYS N    N N N 184 
LYS CA   C N S 185 
LYS C    C N N 186 
LYS O    O N N 187 
LYS CB   C N N 188 
LYS CG   C N N 189 
LYS CD   C N N 190 
LYS CE   C N N 191 
LYS NZ   N N N 192 
LYS OXT  O N N 193 
LYS H    H N N 194 
LYS H2   H N N 195 
LYS HA   H N N 196 
LYS HB2  H N N 197 
LYS HB3  H N N 198 
LYS HG2  H N N 199 
LYS HG3  H N N 200 
LYS HD2  H N N 201 
LYS HD3  H N N 202 
LYS HE2  H N N 203 
LYS HE3  H N N 204 
LYS HZ1  H N N 205 
LYS HZ2  H N N 206 
LYS HZ3  H N N 207 
LYS HXT  H N N 208 
MET N    N N N 209 
MET CA   C N S 210 
MET C    C N N 211 
MET O    O N N 212 
MET CB   C N N 213 
MET CG   C N N 214 
MET SD   S N N 215 
MET CE   C N N 216 
MET OXT  O N N 217 
MET H    H N N 218 
MET H2   H N N 219 
MET HA   H N N 220 
MET HB2  H N N 221 
MET HB3  H N N 222 
MET HG2  H N N 223 
MET HG3  H N N 224 
MET HE1  H N N 225 
MET HE2  H N N 226 
MET HE3  H N N 227 
MET HXT  H N N 228 
PHE N    N N N 229 
PHE CA   C N S 230 
PHE C    C N N 231 
PHE O    O N N 232 
PHE CB   C N N 233 
PHE CG   C Y N 234 
PHE CD1  C Y N 235 
PHE CD2  C Y N 236 
PHE CE1  C Y N 237 
PHE CE2  C Y N 238 
PHE CZ   C Y N 239 
PHE OXT  O N N 240 
PHE H    H N N 241 
PHE H2   H N N 242 
PHE HA   H N N 243 
PHE HB2  H N N 244 
PHE HB3  H N N 245 
PHE HD1  H N N 246 
PHE HD2  H N N 247 
PHE HE1  H N N 248 
PHE HE2  H N N 249 
PHE HZ   H N N 250 
PHE HXT  H N N 251 
PRO N    N N N 252 
PRO CA   C N S 253 
PRO C    C N N 254 
PRO O    O N N 255 
PRO CB   C N N 256 
PRO CG   C N N 257 
PRO CD   C N N 258 
PRO OXT  O N N 259 
PRO H    H N N 260 
PRO HA   H N N 261 
PRO HB2  H N N 262 
PRO HB3  H N N 263 
PRO HG2  H N N 264 
PRO HG3  H N N 265 
PRO HD2  H N N 266 
PRO HD3  H N N 267 
PRO HXT  H N N 268 
SER N    N N N 269 
SER CA   C N S 270 
SER C    C N N 271 
SER O    O N N 272 
SER CB   C N N 273 
SER OG   O N N 274 
SER OXT  O N N 275 
SER H    H N N 276 
SER H2   H N N 277 
SER HA   H N N 278 
SER HB2  H N N 279 
SER HB3  H N N 280 
SER HG   H N N 281 
SER HXT  H N N 282 
THR N    N N N 283 
THR CA   C N S 284 
THR C    C N N 285 
THR O    O N N 286 
THR CB   C N R 287 
THR OG1  O N N 288 
THR CG2  C N N 289 
THR OXT  O N N 290 
THR H    H N N 291 
THR H2   H N N 292 
THR HA   H N N 293 
THR HB   H N N 294 
THR HG1  H N N 295 
THR HG21 H N N 296 
THR HG22 H N N 297 
THR HG23 H N N 298 
THR HXT  H N N 299 
TLA O1   O N N 300 
TLA O11  O N N 301 
TLA C1   C N N 302 
TLA C2   C N R 303 
TLA O2   O N N 304 
TLA C3   C N R 305 
TLA O3   O N N 306 
TLA C4   C N N 307 
TLA O4   O N N 308 
TLA O41  O N N 309 
TLA H11  H N N 310 
TLA H2   H N N 311 
TLA HA   H N N 312 
TLA H3   H N N 313 
TLA HB   H N N 314 
TLA H41  H N N 315 
TRP N    N N N 316 
TRP CA   C N S 317 
TRP C    C N N 318 
TRP O    O N N 319 
TRP CB   C N N 320 
TRP CG   C Y N 321 
TRP CD1  C Y N 322 
TRP CD2  C Y N 323 
TRP NE1  N Y N 324 
TRP CE2  C Y N 325 
TRP CE3  C Y N 326 
TRP CZ2  C Y N 327 
TRP CZ3  C Y N 328 
TRP CH2  C Y N 329 
TRP OXT  O N N 330 
TRP H    H N N 331 
TRP H2   H N N 332 
TRP HA   H N N 333 
TRP HB2  H N N 334 
TRP HB3  H N N 335 
TRP HD1  H N N 336 
TRP HE1  H N N 337 
TRP HE3  H N N 338 
TRP HZ2  H N N 339 
TRP HZ3  H N N 340 
TRP HH2  H N N 341 
TRP HXT  H N N 342 
TYR N    N N N 343 
TYR CA   C N S 344 
TYR C    C N N 345 
TYR O    O N N 346 
TYR CB   C N N 347 
TYR CG   C Y N 348 
TYR CD1  C Y N 349 
TYR CD2  C Y N 350 
TYR CE1  C Y N 351 
TYR CE2  C Y N 352 
TYR CZ   C Y N 353 
TYR OH   O N N 354 
TYR OXT  O N N 355 
TYR H    H N N 356 
TYR H2   H N N 357 
TYR HA   H N N 358 
TYR HB2  H N N 359 
TYR HB3  H N N 360 
TYR HD1  H N N 361 
TYR HD2  H N N 362 
TYR HE1  H N N 363 
TYR HE2  H N N 364 
TYR HH   H N N 365 
TYR HXT  H N N 366 
VAL N    N N N 367 
VAL CA   C N S 368 
VAL C    C N N 369 
VAL O    O N N 370 
VAL CB   C N N 371 
VAL CG1  C N N 372 
VAL CG2  C N N 373 
VAL OXT  O N N 374 
VAL H    H N N 375 
VAL H2   H N N 376 
VAL HA   H N N 377 
VAL HB   H N N 378 
VAL HG11 H N N 379 
VAL HG12 H N N 380 
VAL HG13 H N N 381 
VAL HG21 H N N 382 
VAL HG22 H N N 383 
VAL HG23 H N N 384 
VAL HXT  H N N 385 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HOH O   H1   sing N N 129 
HOH O   H2   sing N N 130 
ILE N   CA   sing N N 131 
ILE N   H    sing N N 132 
ILE N   H2   sing N N 133 
ILE CA  C    sing N N 134 
ILE CA  CB   sing N N 135 
ILE CA  HA   sing N N 136 
ILE C   O    doub N N 137 
ILE C   OXT  sing N N 138 
ILE CB  CG1  sing N N 139 
ILE CB  CG2  sing N N 140 
ILE CB  HB   sing N N 141 
ILE CG1 CD1  sing N N 142 
ILE CG1 HG12 sing N N 143 
ILE CG1 HG13 sing N N 144 
ILE CG2 HG21 sing N N 145 
ILE CG2 HG22 sing N N 146 
ILE CG2 HG23 sing N N 147 
ILE CD1 HD11 sing N N 148 
ILE CD1 HD12 sing N N 149 
ILE CD1 HD13 sing N N 150 
ILE OXT HXT  sing N N 151 
LEU N   CA   sing N N 152 
LEU N   H    sing N N 153 
LEU N   H2   sing N N 154 
LEU CA  C    sing N N 155 
LEU CA  CB   sing N N 156 
LEU CA  HA   sing N N 157 
LEU C   O    doub N N 158 
LEU C   OXT  sing N N 159 
LEU CB  CG   sing N N 160 
LEU CB  HB2  sing N N 161 
LEU CB  HB3  sing N N 162 
LEU CG  CD1  sing N N 163 
LEU CG  CD2  sing N N 164 
LEU CG  HG   sing N N 165 
LEU CD1 HD11 sing N N 166 
LEU CD1 HD12 sing N N 167 
LEU CD1 HD13 sing N N 168 
LEU CD2 HD21 sing N N 169 
LEU CD2 HD22 sing N N 170 
LEU CD2 HD23 sing N N 171 
LEU OXT HXT  sing N N 172 
LYS N   CA   sing N N 173 
LYS N   H    sing N N 174 
LYS N   H2   sing N N 175 
LYS CA  C    sing N N 176 
LYS CA  CB   sing N N 177 
LYS CA  HA   sing N N 178 
LYS C   O    doub N N 179 
LYS C   OXT  sing N N 180 
LYS CB  CG   sing N N 181 
LYS CB  HB2  sing N N 182 
LYS CB  HB3  sing N N 183 
LYS CG  CD   sing N N 184 
LYS CG  HG2  sing N N 185 
LYS CG  HG3  sing N N 186 
LYS CD  CE   sing N N 187 
LYS CD  HD2  sing N N 188 
LYS CD  HD3  sing N N 189 
LYS CE  NZ   sing N N 190 
LYS CE  HE2  sing N N 191 
LYS CE  HE3  sing N N 192 
LYS NZ  HZ1  sing N N 193 
LYS NZ  HZ2  sing N N 194 
LYS NZ  HZ3  sing N N 195 
LYS OXT HXT  sing N N 196 
MET N   CA   sing N N 197 
MET N   H    sing N N 198 
MET N   H2   sing N N 199 
MET CA  C    sing N N 200 
MET CA  CB   sing N N 201 
MET CA  HA   sing N N 202 
MET C   O    doub N N 203 
MET C   OXT  sing N N 204 
MET CB  CG   sing N N 205 
MET CB  HB2  sing N N 206 
MET CB  HB3  sing N N 207 
MET CG  SD   sing N N 208 
MET CG  HG2  sing N N 209 
MET CG  HG3  sing N N 210 
MET SD  CE   sing N N 211 
MET CE  HE1  sing N N 212 
MET CE  HE2  sing N N 213 
MET CE  HE3  sing N N 214 
MET OXT HXT  sing N N 215 
PHE N   CA   sing N N 216 
PHE N   H    sing N N 217 
PHE N   H2   sing N N 218 
PHE CA  C    sing N N 219 
PHE CA  CB   sing N N 220 
PHE CA  HA   sing N N 221 
PHE C   O    doub N N 222 
PHE C   OXT  sing N N 223 
PHE CB  CG   sing N N 224 
PHE CB  HB2  sing N N 225 
PHE CB  HB3  sing N N 226 
PHE CG  CD1  doub Y N 227 
PHE CG  CD2  sing Y N 228 
PHE CD1 CE1  sing Y N 229 
PHE CD1 HD1  sing N N 230 
PHE CD2 CE2  doub Y N 231 
PHE CD2 HD2  sing N N 232 
PHE CE1 CZ   doub Y N 233 
PHE CE1 HE1  sing N N 234 
PHE CE2 CZ   sing Y N 235 
PHE CE2 HE2  sing N N 236 
PHE CZ  HZ   sing N N 237 
PHE OXT HXT  sing N N 238 
PRO N   CA   sing N N 239 
PRO N   CD   sing N N 240 
PRO N   H    sing N N 241 
PRO CA  C    sing N N 242 
PRO CA  CB   sing N N 243 
PRO CA  HA   sing N N 244 
PRO C   O    doub N N 245 
PRO C   OXT  sing N N 246 
PRO CB  CG   sing N N 247 
PRO CB  HB2  sing N N 248 
PRO CB  HB3  sing N N 249 
PRO CG  CD   sing N N 250 
PRO CG  HG2  sing N N 251 
PRO CG  HG3  sing N N 252 
PRO CD  HD2  sing N N 253 
PRO CD  HD3  sing N N 254 
PRO OXT HXT  sing N N 255 
SER N   CA   sing N N 256 
SER N   H    sing N N 257 
SER N   H2   sing N N 258 
SER CA  C    sing N N 259 
SER CA  CB   sing N N 260 
SER CA  HA   sing N N 261 
SER C   O    doub N N 262 
SER C   OXT  sing N N 263 
SER CB  OG   sing N N 264 
SER CB  HB2  sing N N 265 
SER CB  HB3  sing N N 266 
SER OG  HG   sing N N 267 
SER OXT HXT  sing N N 268 
THR N   CA   sing N N 269 
THR N   H    sing N N 270 
THR N   H2   sing N N 271 
THR CA  C    sing N N 272 
THR CA  CB   sing N N 273 
THR CA  HA   sing N N 274 
THR C   O    doub N N 275 
THR C   OXT  sing N N 276 
THR CB  OG1  sing N N 277 
THR CB  CG2  sing N N 278 
THR CB  HB   sing N N 279 
THR OG1 HG1  sing N N 280 
THR CG2 HG21 sing N N 281 
THR CG2 HG22 sing N N 282 
THR CG2 HG23 sing N N 283 
THR OXT HXT  sing N N 284 
TLA O1  C1   doub N N 285 
TLA O11 C1   sing N N 286 
TLA O11 H11  sing N N 287 
TLA C1  C2   sing N N 288 
TLA C2  O2   sing N N 289 
TLA C2  C3   sing N N 290 
TLA C2  H2   sing N N 291 
TLA O2  HA   sing N N 292 
TLA C3  O3   sing N N 293 
TLA C3  C4   sing N N 294 
TLA C3  H3   sing N N 295 
TLA O3  HB   sing N N 296 
TLA C4  O4   doub N N 297 
TLA C4  O41  sing N N 298 
TLA O41 H41  sing N N 299 
TRP N   CA   sing N N 300 
TRP N   H    sing N N 301 
TRP N   H2   sing N N 302 
TRP CA  C    sing N N 303 
TRP CA  CB   sing N N 304 
TRP CA  HA   sing N N 305 
TRP C   O    doub N N 306 
TRP C   OXT  sing N N 307 
TRP CB  CG   sing N N 308 
TRP CB  HB2  sing N N 309 
TRP CB  HB3  sing N N 310 
TRP CG  CD1  doub Y N 311 
TRP CG  CD2  sing Y N 312 
TRP CD1 NE1  sing Y N 313 
TRP CD1 HD1  sing N N 314 
TRP CD2 CE2  doub Y N 315 
TRP CD2 CE3  sing Y N 316 
TRP NE1 CE2  sing Y N 317 
TRP NE1 HE1  sing N N 318 
TRP CE2 CZ2  sing Y N 319 
TRP CE3 CZ3  doub Y N 320 
TRP CE3 HE3  sing N N 321 
TRP CZ2 CH2  doub Y N 322 
TRP CZ2 HZ2  sing N N 323 
TRP CZ3 CH2  sing Y N 324 
TRP CZ3 HZ3  sing N N 325 
TRP CH2 HH2  sing N N 326 
TRP OXT HXT  sing N N 327 
TYR N   CA   sing N N 328 
TYR N   H    sing N N 329 
TYR N   H2   sing N N 330 
TYR CA  C    sing N N 331 
TYR CA  CB   sing N N 332 
TYR CA  HA   sing N N 333 
TYR C   O    doub N N 334 
TYR C   OXT  sing N N 335 
TYR CB  CG   sing N N 336 
TYR CB  HB2  sing N N 337 
TYR CB  HB3  sing N N 338 
TYR CG  CD1  doub Y N 339 
TYR CG  CD2  sing Y N 340 
TYR CD1 CE1  sing Y N 341 
TYR CD1 HD1  sing N N 342 
TYR CD2 CE2  doub Y N 343 
TYR CD2 HD2  sing N N 344 
TYR CE1 CZ   doub Y N 345 
TYR CE1 HE1  sing N N 346 
TYR CE2 CZ   sing Y N 347 
TYR CE2 HE2  sing N N 348 
TYR CZ  OH   sing N N 349 
TYR OH  HH   sing N N 350 
TYR OXT HXT  sing N N 351 
VAL N   CA   sing N N 352 
VAL N   H    sing N N 353 
VAL N   H2   sing N N 354 
VAL CA  C    sing N N 355 
VAL CA  CB   sing N N 356 
VAL CA  HA   sing N N 357 
VAL C   O    doub N N 358 
VAL C   OXT  sing N N 359 
VAL CB  CG1  sing N N 360 
VAL CB  CG2  sing N N 361 
VAL CB  HB   sing N N 362 
VAL CG1 HG11 sing N N 363 
VAL CG1 HG12 sing N N 364 
VAL CG1 HG13 sing N N 365 
VAL CG2 HG21 sing N N 366 
VAL CG2 HG22 sing N N 367 
VAL CG2 HG23 sing N N 368 
VAL OXT HXT  sing N N 369 
# 
_pdbx_audit_support.funding_organization   'Max Planck Society' 
_pdbx_audit_support.country                Germany 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5FGT 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9G2J 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017286 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.017286 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006652 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 0.8669   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . ALA A 1 1   ? 18.011 7.325  27.912 1.000 38.837  0 1    ALA A N   1 ? 
ATOM   2    C CA  . ALA A 1 1   ? 16.589 7.659  27.651 1.000 36.233  0 1    ALA A CA  1 ? 
ATOM   3    C C   . ALA A 1 1   ? 16.575 8.642  26.492 1.000 29.731  0 1    ALA A C   1 ? 
ATOM   4    O O   . ALA A 1 1   ? 17.524 9.389  26.325 1.000 32.441  0 1    ALA A O   1 ? 
ATOM   5    C CB  . ALA A 1 1   ? 15.944 8.263  28.862 1.000 39.162  0 1    ALA A CB  1 ? 
ATOM   6    N N   . THR A 1 2   ? 15.488 8.641  25.731 1.000 29.740  0 2    THR A N   1 ? 
ATOM   7    C CA  A THR A 1 2   ? 15.397 9.624  24.667 0.500 27.141  0 2    THR A CA  1 ? 
ATOM   8    C CA  B THR A 1 2   ? 15.278 9.527  24.602 0.500 26.383  0 2    THR A CA  1 ? 
ATOM   9    C C   . THR A 1 2   ? 14.345 10.656 25.058 1.000 25.381  0 2    THR A C   1 ? 
ATOM   10   O O   . THR A 1 2   ? 13.319 10.347 25.621 1.000 26.742  0 2    THR A O   1 ? 
ATOM   11   C CB  A THR A 1 2   ? 15.110 9.022  23.296 0.500 28.419  0 2    THR A CB  1 ? 
ATOM   12   C CB  B THR A 1 2   ? 14.598 8.716  23.494 0.500 27.847  0 2    THR A CB  1 ? 
ATOM   13   O OG1 A THR A 1 2   ? 13.821 8.437  23.447 0.500 32.693  0 2    THR A OG1 1 ? 
ATOM   14   O OG1 B THR A 1 2   ? 15.376 7.542  23.266 0.500 26.098  0 2    THR A OG1 1 ? 
ATOM   15   C CG2 A THR A 1 2   ? 16.177 8.036  22.891 0.500 28.539  0 2    THR A CG2 1 ? 
ATOM   16   C CG2 B THR A 1 2   ? 14.387 9.479  22.209 0.500 27.406  0 2    THR A CG2 1 ? 
ATOM   17   N N   . PHE A 1 3   ? 14.695 11.894 24.784 1.000 25.664  0 3    PHE A N   1 ? 
ATOM   18   C CA  . PHE A 1 3   ? 13.757 12.982 24.945 1.000 24.448  0 3    PHE A CA  1 ? 
ATOM   19   C C   . PHE A 1 3   ? 13.561 13.599 23.565 1.000 21.804  0 3    PHE A C   1 ? 
ATOM   20   O O   . PHE A 1 3   ? 14.522 13.945 22.907 1.000 28.241  0 3    PHE A O   1 ? 
ATOM   21   C CB  . PHE A 1 3   ? 14.338 14.067 25.833 1.000 23.887  0 3    PHE A CB  1 ? 
ATOM   22   C CG  . PHE A 1 3   ? 14.391 13.738 27.296 1.000 26.990  0 3    PHE A CG  1 ? 
ATOM   23   C CD1 . PHE A 1 3   ? 15.207 12.726 27.772 1.000 26.168  0 3    PHE A CD1 1 ? 
ATOM   24   C CD2 . PHE A 1 3   ? 13.581 14.390 28.196 1.000 27.802  0 3    PHE A CD2 1 ? 
ATOM   25   C CE1 . PHE A 1 3   ? 15.244 12.417 29.122 1.000 30.000  0 3    PHE A CE1 1 ? 
ATOM   26   C CE2 . PHE A 1 3   ? 13.618 14.084 29.543 1.000 28.435  0 3    PHE A CE2 1 ? 
ATOM   27   C CZ  . PHE A 1 3   ? 14.451 13.097 30.000 1.000 28.535  0 3    PHE A CZ  1 ? 
ATOM   28   N N   . GLU A 1 4   ? 12.322 13.749 23.172 1.000 21.858  0 4    GLU A N   1 ? 
ATOM   29   C CA  . GLU A 1 4   ? 12.057 14.505 21.978 1.000 21.090  0 4    GLU A CA  1 ? 
ATOM   30   C C   . GLU A 1 4   ? 11.604 15.873 22.478 1.000 22.685  0 4    GLU A C   1 ? 
ATOM   31   O O   . GLU A 1 4   ? 10.671 15.947 23.276 1.000 24.929  0 4    GLU A O   1 ? 
ATOM   32   C CB  . GLU A 1 4   ? 10.948 13.876 21.169 1.000 25.518  0 4    GLU A CB  1 ? 
ATOM   33   C CG  . GLU A 1 4   ? 10.824 14.556 19.834 1.000 28.192  0 4    GLU A CG  1 ? 
ATOM   34   C CD  . GLU A 1 4   ? 9.758  14.005 18.909 1.000 30.488  0 4    GLU A CD  1 ? 
ATOM   35   O OE1 . GLU A 1 4   ? 8.663  13.811 19.377 1.000 29.906  0 4    GLU A OE1 1 ? 
ATOM   36   O OE2 . GLU A 1 4   ? 10.081 13.792 17.725 1.000 32.414  0 4    GLU A OE2 1 ? 
ATOM   37   N N   . ILE A 1 5   ? 12.251 16.889 21.962 1.000 21.398  0 5    ILE A N   1 ? 
ATOM   38   C CA  . ILE A 1 5   ? 11.932 18.246 22.377 1.000 20.415  0 5    ILE A CA  1 ? 
ATOM   39   C C   . ILE A 1 5   ? 11.317 18.897 21.155 1.000 20.540  0 5    ILE A C   1 ? 
ATOM   40   O O   . ILE A 1 5   ? 11.933 19.011 20.107 1.000 21.907  0 5    ILE A O   1 ? 
ATOM   41   C CB  . ILE A 1 5   ? 13.193 18.954 22.854 1.000 21.856  0 5    ILE A CB  1 ? 
ATOM   42   C CG1 . ILE A 1 5   ? 13.833 18.208 24.029 1.000 23.664  0 5    ILE A CG1 1 ? 
ATOM   43   C CG2 . ILE A 1 5   ? 12.854 20.389 23.236 1.000 23.689  0 5    ILE A CG2 1 ? 
ATOM   44   C CD1 . ILE A 1 5   ? 15.247 18.670 24.352 1.000 30.396  0 5    ILE A CD1 1 ? 
ATOM   45   N N   . VAL A 1 6   ? 10.089 19.367 21.338 1.000 20.331  0 6    VAL A N   1 ? 
ATOM   46   C CA  . VAL A 1 6   ? 9.300  19.858 20.231 1.000 21.021  0 6    VAL A CA  1 ? 
ATOM   47   C C   . VAL A 1 6   ? 8.967  21.321 20.494 1.000 19.786  0 6    VAL A C   1 ? 
ATOM   48   O O   . VAL A 1 6   ? 8.439  21.616 21.560 1.000 21.676  0 6    VAL A O   1 ? 
ATOM   49   C CB  . VAL A 1 6   ? 8.006  19.077 20.094 1.000 24.964  0 6    VAL A CB  1 ? 
ATOM   50   C CG1 . VAL A 1 6   ? 7.139  19.650 18.960 1.000 23.639  0 6    VAL A CG1 1 ? 
ATOM   51   C CG2 . VAL A 1 6   ? 8.325  17.610 19.887 1.000 26.036  0 6    VAL A CG2 1 ? 
ATOM   52   N N   . ASN A 1 7   ? 9.239  22.185 19.518 1.000 20.067  0 7    ASN A N   1 ? 
ATOM   53   C CA  . ASN A 1 7   ? 8.833  23.551 19.669 1.000 19.620  0 7    ASN A CA  1 ? 
ATOM   54   C C   . ASN A 1 7   ? 7.509  23.743 18.911 1.000 19.962  0 7    ASN A C   1 ? 
ATOM   55   O O   . ASN A 1 7   ? 7.535  23.843 17.701 1.000 22.831  0 7    ASN A O   1 ? 
ATOM   56   C CB  . ASN A 1 7   ? 9.888  24.473 19.107 1.000 21.438  0 7    ASN A CB  1 ? 
ATOM   57   C CG  . ASN A 1 7   ? 9.428  25.896 19.265 1.000 21.192  0 7    ASN A CG  1 ? 
ATOM   58   O OD1 . ASN A 1 7   ? 8.577  26.165 20.078 1.000 22.177  0 7    ASN A OD1 1 ? 
ATOM   59   N ND2 . ASN A 1 7   ? 10.009 26.774 18.483 1.000 21.872  0 7    ASN A ND2 1 ? 
ATOM   60   N N   . ARG A 1 8   ? 6.392  23.788 19.625 1.000 18.954  0 8    ARG A N   1 ? 
ATOM   61   C CA  . ARG A 1 8   ? 5.111  24.103 19.027 1.000 20.679  0 8    ARG A CA  1 ? 
ATOM   62   C C   . ARG A 1 8   ? 4.799  25.604 19.088 1.000 22.414  0 8    ARG A C   1 ? 
ATOM   63   O O   . ARG A 1 8   ? 3.755  26.062 18.592 1.000 21.314  0 8    ARG A O   1 ? 
ATOM   64   C CB  . ARG A 1 8   ? 4.047  23.248 19.698 1.000 21.351  0 8    ARG A CB  1 ? 
ATOM   65   C CG  . ARG A 1 8   ? 2.713  23.303 18.997 1.000 23.235  0 8    ARG A CG  1 ? 
ATOM   66   C CD  . ARG A 1 8   ? 1.752  22.335 19.596 1.000 25.574  0 8    ARG A CD  1 ? 
ATOM   67   N NE  . ARG A 1 8   ? 2.192  20.983 19.369 1.000 24.209  0 8    ARG A NE  1 ? 
ATOM   68   C CZ  . ARG A 1 8   ? 1.872  19.945 20.111 1.000 26.902  0 8    ARG A CZ  1 ? 
ATOM   69   N NH1 . ARG A 1 8   ? 1.146  20.082 21.207 1.000 28.930  0 8    ARG A NH1 1 ? 
ATOM   70   N NH2 . ARG A 1 8   ? 2.377  18.769 19.823 1.000 27.088  0 8    ARG A NH2 1 ? 
ATOM   71   N N   . CYS A 1 9   ? 5.715  26.386 19.626 1.000 19.859  0 9    CYS A N   1 ? 
ATOM   72   C CA  . CYS A 1 9   ? 5.544  27.821 19.669 1.000 20.324  0 9    CYS A CA  1 ? 
ATOM   73   C C   . CYS A 1 9   ? 5.590  28.366 18.251 1.000 21.966  0 9    CYS A C   1 ? 
ATOM   74   O O   . CYS A 1 9   ? 6.209  27.800 17.356 1.000 23.040  0 9    CYS A O   1 ? 
ATOM   75   C CB  . CYS A 1 9   ? 6.625  28.511 20.498 1.000 21.632  0 9    CYS A CB  1 ? 
ATOM   76   S SG  . CYS A 1 9   ? 6.747  27.844 22.171 1.000 22.736  0 9    CYS A SG  1 ? 
ATOM   77   N N   . SER A 1 10  ? 4.968  29.528 18.081 1.000 22.239  0 10   SER A N   1 ? 
ATOM   78   C CA  . SER A 1 10  ? 4.999  30.220 16.800 1.000 26.094  0 10   SER A CA  1 ? 
ATOM   79   C C   . SER A 1 10  ? 6.325  30.931 16.576 1.000 28.949  0 10   SER A C   1 ? 
ATOM   80   O O   . SER A 1 10  ? 6.609  31.438 15.508 1.000 33.158  0 10   SER A O   1 ? 
ATOM   81   C CB  . SER A 1 10  ? 3.802  31.147 16.674 1.000 28.366  0 10   SER A CB  1 ? 
ATOM   82   O OG  . SER A 1 10  ? 3.900  32.104 17.685 1.000 31.388  0 10   SER A OG  1 ? 
ATOM   83   N N   . TYR A 1 11  ? 7.149  31.004 17.614 1.000 24.632  0 11   TYR A N   1 ? 
ATOM   84   C CA  . TYR A 1 11  ? 8.428  31.645 17.569 1.000 23.540  0 11   TYR A CA  1 ? 
ATOM   85   C C   . TYR A 1 11  ? 9.524  30.600 17.789 1.000 22.691  0 11   TYR A C   1 ? 
ATOM   86   O O   . TYR A 1 11  ? 9.303  29.531 18.350 1.000 24.063  0 11   TYR A O   1 ? 
ATOM   87   C CB  . TYR A 1 11  ? 8.464  32.752 18.634 1.000 26.493  0 11   TYR A CB  1 ? 
ATOM   88   C CG  . TYR A 1 11  ? 8.015  32.353 19.998 1.000 26.852  0 11   TYR A CG  1 ? 
ATOM   89   C CD1 . TYR A 1 11  ? 8.894  31.833 20.936 1.000 25.812  0 11   TYR A CD1 1 ? 
ATOM   90   C CD2 . TYR A 1 11  ? 6.719  32.545 20.408 1.000 25.854  0 11   TYR A CD2 1 ? 
ATOM   91   C CE1 . TYR A 1 11  ? 8.461  31.418 22.173 1.000 26.087  0 11   TYR A CE1 1 ? 
ATOM   92   C CE2 . TYR A 1 11  ? 6.285  32.180 21.659 1.000 27.132  0 11   TYR A CE2 1 ? 
ATOM   93   C CZ  . TYR A 1 11  ? 7.174  31.649 22.572 1.000 26.859  0 11   TYR A CZ  1 ? 
ATOM   94   O OH  . TYR A 1 11  ? 6.729  31.265 23.808 1.000 28.361  0 11   TYR A OH  1 ? 
ATOM   95   N N   . THR A 1 12  ? 10.715 30.960 17.333 1.000 23.496  0 12   THR A N   1 ? 
ATOM   96   C CA  . THR A 1 12  ? 11.908 30.165 17.504 1.000 20.863  0 12   THR A CA  1 ? 
ATOM   97   C C   . THR A 1 12  ? 12.280 30.178 18.969 1.000 23.078  0 12   THR A C   1 ? 
ATOM   98   O O   . THR A 1 12  ? 12.247 31.207 19.632 1.000 24.130  0 12   THR A O   1 ? 
ATOM   99   C CB  . THR A 1 12  ? 13.073 30.696 16.690 1.000 25.071  0 12   THR A CB  1 ? 
ATOM   100  O OG1 . THR A 1 12  ? 12.616 30.660 15.342 1.000 26.422  0 12   THR A OG1 1 ? 
ATOM   101  C CG2 . THR A 1 12  ? 14.347 29.906 16.822 1.000 24.503  0 12   THR A CG2 1 ? 
ATOM   102  N N   . VAL A 1 13  ? 12.685 29.026 19.417 1.000 21.557  0 13   VAL A N   1 ? 
ATOM   103  C CA  . VAL A 1 13  ? 13.304 28.888 20.724 1.000 21.186  0 13   VAL A CA  1 ? 
ATOM   104  C C   . VAL A 1 13  ? 14.613 28.157 20.545 1.000 22.568  0 13   VAL A C   1 ? 
ATOM   105  O O   . VAL A 1 13  ? 14.872 27.518 19.536 1.000 24.391  0 13   VAL A O   1 ? 
ATOM   106  C CB  . VAL A 1 13  ? 12.431 28.168 21.748 1.000 23.586  0 13   VAL A CB  1 ? 
ATOM   107  C CG1 . VAL A 1 13  ? 11.108 28.857 21.925 1.000 25.798  0 13   VAL A CG1 1 ? 
ATOM   108  C CG2 . VAL A 1 13  ? 12.262 26.709 21.419 1.000 26.167  0 13   VAL A CG2 1 ? 
ATOM   109  N N   . TRP A 1 14  ? 15.482 28.384 21.526 1.000 20.980  0 14   TRP A N   1 ? 
ATOM   110  C CA  . TRP A 1 14  ? 16.735 27.692 21.579 1.000 21.240  0 14   TRP A CA  1 ? 
ATOM   111  C C   . TRP A 1 14  ? 16.677 26.775 22.775 1.000 23.371  0 14   TRP A C   1 ? 
ATOM   112  O O   . TRP A 1 14  ? 16.744 27.210 23.912 1.000 21.799  0 14   TRP A O   1 ? 
ATOM   113  C CB  . TRP A 1 14  ? 17.889 28.649 21.615 1.000 23.586  0 14   TRP A CB  1 ? 
ATOM   114  C CG  . TRP A 1 14  ? 18.094 29.345 20.322 1.000 21.596  0 14   TRP A CG  1 ? 
ATOM   115  C CD1 . TRP A 1 14  ? 19.088 29.089 19.423 1.000 26.020  0 14   TRP A CD1 1 ? 
ATOM   116  C CD2 . TRP A 1 14  ? 17.338 30.438 19.807 1.000 21.486  0 14   TRP A CD2 1 ? 
ATOM   117  N NE1 . TRP A 1 14  ? 19.037 29.993 18.398 1.000 24.800  0 14   TRP A NE1 1 ? 
ATOM   118  C CE2 . TRP A 1 14  ? 17.949 30.789 18.572 1.000 23.891  0 14   TRP A CE2 1 ? 
ATOM   119  C CE3 . TRP A 1 14  ? 16.282 31.212 20.283 1.000 23.664  0 14   TRP A CE3 1 ? 
ATOM   120  C CZ2 . TRP A 1 14  ? 17.510 31.855 17.828 1.000 25.506  0 14   TRP A CZ2 1 ? 
ATOM   121  C CZ3 . TRP A 1 14  ? 15.795 32.220 19.484 1.000 26.090  0 14   TRP A CZ3 1 ? 
ATOM   122  C CH2 . TRP A 1 14  ? 16.422 32.538 18.288 1.000 24.809  0 14   TRP A CH2 1 ? 
ATOM   123  N N   . ALA A 1 15  ? 16.427 25.501 22.491 1.000 20.771  0 15   ALA A N   1 ? 
ATOM   124  C CA  . ALA A 1 15  ? 16.292 24.515 23.539 1.000 20.479  0 15   ALA A CA  1 ? 
ATOM   125  C C   . ALA A 1 15  ? 17.646 24.375 24.209 1.000 19.446  0 15   ALA A C   1 ? 
ATOM   126  O O   . ALA A 1 15  ? 18.663 24.540 23.581 1.000 21.290  0 15   ALA A O   1 ? 
ATOM   127  C CB  . ALA A 1 15  ? 15.834 23.187 22.991 1.000 21.686  0 15   ALA A CB  1 ? 
ATOM   128  N N   . ALA A 1 16  ? 17.631 23.976 25.468 1.000 21.146  0 16   ALA A N   1 ? 
ATOM   129  C CA  . ALA A 1 16  ? 18.816 23.727 26.245 1.000 22.846  0 16   ALA A CA  1 ? 
ATOM   130  C C   . ALA A 1 16  ? 18.551 22.489 27.079 1.000 22.346  0 16   ALA A C   1 ? 
ATOM   131  O O   . ALA A 1 16  ? 17.444 22.233 27.572 1.000 23.455  0 16   ALA A O   1 ? 
ATOM   132  C CB  . ALA A 1 16  ? 19.123 24.934 27.111 1.000 23.206  0 16   ALA A CB  1 ? 
ATOM   133  N N   . ALA A 1 17  ? 19.622 21.741 27.344 1.000 22.001  0 17   ALA A N   1 ? 
ATOM   134  C CA  . ALA A 1 17  ? 19.555 20.536 28.131 1.000 22.822  0 17   ALA A CA  1 ? 
ATOM   135  C C   . ALA A 1 17  ? 20.878 20.395 28.864 1.000 23.596  0 17   ALA A C   1 ? 
ATOM   136  O O   . ALA A 1 17  ? 21.905 20.347 28.211 1.000 25.977  0 17   ALA A O   1 ? 
ATOM   137  C CB  . ALA A 1 17  ? 19.288 19.374 27.234 1.000 26.785  0 17   ALA A CB  1 ? 
ATOM   138  N N   . SER A 1 18  ? 20.813 20.349 30.192 1.000 22.753  0 18   SER A N   1 ? 
ATOM   139  C CA  . SER A 1 18  ? 22.011 20.369 31.014 1.000 23.167  0 18   SER A CA  1 ? 
ATOM   140  C C   . SER A 1 18  ? 21.760 19.614 32.305 1.000 25.160  0 18   SER A C   1 ? 
ATOM   141  O O   . SER A 1 18  ? 20.635 19.516 32.732 1.000 24.172  0 18   SER A O   1 ? 
ATOM   142  C CB  . SER A 1 18  ? 22.393 21.808 31.321 1.000 26.915  0 18   SER A CB  1 ? 
ATOM   143  O OG  . SER A 1 18  ? 23.526 21.891 32.193 1.000 32.444  0 18   SER A OG  1 ? 
ATOM   144  N N   . LYS A 1 19  ? 22.835 19.157 32.965 1.000 28.174  0 19   LYS A N   1 ? 
ATOM   145  C CA  . LYS A 1 19  ? 22.690 18.675 34.333 1.000 30.166  0 19   LYS A CA  1 ? 
ATOM   146  C C   . LYS A 1 19  ? 23.490 19.550 35.284 1.000 32.485  0 19   LYS A C   1 ? 
ATOM   147  O O   . LYS A 1 19  ? 23.760 19.120 36.396 1.000 37.721  0 19   LYS A O   1 ? 
ATOM   148  C CB  . LYS A 1 19  ? 23.045 17.192 34.481 1.000 31.525  0 19   LYS A CB  1 ? 
ATOM   149  C CG  . LYS A 1 19  ? 24.446 16.793 34.048 1.000 37.739  0 19   LYS A CG  1 ? 
ATOM   150  C CD  . LYS A 1 19  ? 24.684 15.286 34.300 1.000 43.270  0 19   LYS A CD  1 ? 
ATOM   151  C CE  . LYS A 1 19  ? 26.129 14.856 34.169 1.000 55.256  0 19   LYS A CE  1 ? 
ATOM   152  N NZ  . LYS A 1 19  ? 26.930 15.368 35.320 1.000 58.975  0 19   LYS A NZ  1 ? 
ATOM   153  N N   . GLY A 1 20  ? 23.808 20.766 34.859 1.000 30.041  0 20   GLY A N   1 ? 
ATOM   154  C CA  . GLY A 1 20  ? 24.351 21.790 35.738 1.000 36.313  0 20   GLY A CA  1 ? 
ATOM   155  C C   . GLY A 1 20  ? 25.860 21.913 35.605 1.000 33.355  0 20   GLY A C   1 ? 
ATOM   156  O O   . GLY A 1 20  ? 26.378 23.016 35.626 1.000 35.988  0 20   GLY A O   1 ? 
ATOM   157  N N   . ASP A 1 21  ? 26.540 20.775 35.434 1.000 35.121  0 21   ASP A N   1 ? 
ATOM   158  C CA  . ASP A 1 21  ? 27.986 20.794 35.294 1.000 39.119  0 21   ASP A CA  1 ? 
ATOM   159  C C   . ASP A 1 21  ? 28.386 20.197 33.960 1.000 40.061  0 21   ASP A C   1 ? 
ATOM   160  O O   . ASP A 1 21  ? 29.555 20.029 33.694 1.000 41.177  0 21   ASP A O   1 ? 
ATOM   161  C CB  . ASP A 1 21  ? 28.627 20.025 36.445 1.000 43.001  0 21   ASP A CB  1 ? 
ATOM   162  C CG  . ASP A 1 21  ? 28.157 18.595 36.625 1.000 47.687  0 21   ASP A CG  1 ? 
ATOM   163  O OD1 . ASP A 1 21  ? 27.312 18.097 35.841 1.000 40.584  0 21   ASP A OD1 1 ? 
ATOM   164  O OD2 . ASP A 1 21  ? 28.646 17.976 37.558 1.000 61.032  0 21   ASP A OD2 1 ? 
ATOM   165  N N   . ALA A 1 22  ? 27.419 19.846 33.125 1.000 33.281  0 22   ALA A N   1 ? 
ATOM   166  C CA  . ALA A 1 22  ? 27.695 19.355 31.798 1.000 30.336  0 22   ALA A CA  1 ? 
ATOM   167  C C   . ALA A 1 22  ? 26.435 19.531 30.950 1.000 27.384  0 22   ALA A C   1 ? 
ATOM   168  O O   . ALA A 1 22  ? 25.325 19.451 31.514 1.000 29.269  0 22   ALA A O   1 ? 
ATOM   169  C CB  . ALA A 1 22  ? 28.031 17.885 31.835 1.000 31.637  0 22   ALA A CB  1 ? 
ATOM   170  N N   . ALA A 1 23  ? 26.670 19.549 29.629 1.000 29.253  0 23   ALA A N   1 ? 
ATOM   171  C CA  . ALA A 1 23  ? 25.612 19.438 28.630 1.000 28.696  0 23   ALA A CA  1 ? 
ATOM   172  C C   . ALA A 1 23  ? 25.001 18.051 28.710 1.000 35.124  0 23   ALA A C   1 ? 
ATOM   173  O O   . ALA A 1 23  ? 25.661 17.071 29.057 1.000 32.067  0 23   ALA A O   1 ? 
ATOM   174  C CB  . ALA A 1 23  ? 26.126 19.694 27.244 1.000 31.181  0 23   ALA A CB  1 ? 
ATOM   175  N N   . LEU A 1 24  ? 23.715 17.981 28.379 1.000 25.981  0 24   LEU A N   1 ? 
ATOM   176  C CA  . LEU A 1 24  ? 23.086 16.739 27.983 1.000 26.644  0 24   LEU A CA  1 ? 
ATOM   177  C C   . LEU A 1 24  ? 22.999 16.707 26.466 1.000 28.549  0 24   LEU A C   1 ? 
ATOM   178  O O   . LEU A 1 24  ? 22.532 17.627 25.821 1.000 28.353  0 24   LEU A O   1 ? 
ATOM   179  C CB  . LEU A 1 24  ? 21.698 16.636 28.589 1.000 27.518  0 24   LEU A CB  1 ? 
ATOM   180  C CG  . LEU A 1 24  ? 21.681 16.602 30.117 1.000 29.734  0 24   LEU A CG  1 ? 
ATOM   181  C CD1 . LEU A 1 24  ? 20.250 16.523 30.623 1.000 29.259  0 24   LEU A CD1 1 ? 
ATOM   182  C CD2 . LEU A 1 24  ? 22.503 15.412 30.637 1.000 32.898  0 24   LEU A CD2 1 ? 
ATOM   183  N N   . ASP A 1 25  ? 23.526 15.640 25.872 1.000 32.042  0 25   ASP A N   1 ? 
ATOM   184  C CA  . ASP A 1 25  ? 23.612 15.553 24.437 1.000 30.974  0 25   ASP A CA  1 ? 
ATOM   185  C C   . ASP A 1 25  ? 24.377 16.783 23.967 1.000 28.796  0 25   ASP A C   1 ? 
ATOM   186  O O   . ASP A 1 25  ? 25.336 17.171 24.616 1.000 29.524  0 25   ASP A O   1 ? 
ATOM   187  C CB  . ASP A 1 25  ? 22.216 15.340 23.866 1.000 32.160  0 25   ASP A CB  1 ? 
ATOM   188  C CG  . ASP A 1 25  ? 22.201 14.789 22.456 1.000 35.443  0 25   ASP A CG  1 ? 
ATOM   189  O OD1 . ASP A 1 25  ? 22.519 15.538 21.546 1.000 35.148  0 25   ASP A OD1 1 ? 
ATOM   190  O OD2 . ASP A 1 25  ? 21.785 13.653 22.304 1.000 33.027  0 25   ASP A OD2 1 ? 
ATOM   191  N N   . ALA A 1 26  ? 23.952 17.427 22.885 1.000 27.095  0 26   ALA A N   1 ? 
ATOM   192  C CA  . ALA A 1 26  ? 24.632 18.600 22.370 1.000 29.717  0 26   ALA A CA  1 ? 
ATOM   193  C C   . ALA A 1 26  ? 24.432 19.819 23.278 1.000 29.939  0 26   ALA A C   1 ? 
ATOM   194  O O   . ALA A 1 26  ? 25.140 20.793 23.141 1.000 34.224  0 26   ALA A O   1 ? 
ATOM   195  C CB  . ALA A 1 26  ? 24.124 18.903 20.976 1.000 34.084  0 26   ALA A CB  1 ? 
ATOM   196  N N   . GLY A 1 27  ? 23.468 19.782 24.195 1.000 28.029  0 27   GLY A N   1 ? 
ATOM   197  C CA  . GLY A 1 27  ? 23.333 20.855 25.176 1.000 26.696  0 27   GLY A CA  1 ? 
ATOM   198  C C   . GLY A 1 27  ? 22.410 21.984 24.732 1.000 26.965  0 27   GLY A C   1 ? 
ATOM   199  O O   . GLY A 1 27  ? 21.857 22.695 25.550 1.000 27.213  0 27   GLY A O   1 ? 
ATOM   200  N N   . GLY A 1 28  ? 22.238 22.161 23.445 1.000 25.019  0 28   GLY A N   1 ? 
ATOM   201  C CA  . GLY A 1 28  ? 21.363 23.211 22.970 1.000 26.519  0 28   GLY A CA  1 ? 
ATOM   202  C C   . GLY A 1 28  ? 21.254 23.184 21.470 1.000 27.154  0 28   GLY A C   1 ? 
ATOM   203  O O   . GLY A 1 28  ? 22.127 22.704 20.761 1.000 28.075  0 28   GLY A O   1 ? 
ATOM   204  N N   . ARG A 1 29  ? 20.136 23.719 20.996 1.000 24.367  0 29   ARG A N   1 ? 
ATOM   205  C CA  . ARG A 1 29  ? 19.918 23.817 19.581 1.000 23.983  0 29   ARG A CA  1 ? 
ATOM   206  C C   . ARG A 1 29  ? 18.797 24.791 19.321 1.000 23.080  0 29   ARG A C   1 ? 
ATOM   207  O O   . ARG A 1 29  ? 17.869 24.865 20.099 1.000 24.187  0 29   ARG A O   1 ? 
ATOM   208  C CB  . ARG A 1 29  ? 19.470 22.449 19.061 1.000 28.150  0 29   ARG A CB  1 ? 
ATOM   209  C CG  . ARG A 1 29  ? 20.051 22.178 17.691 1.000 33.238  0 29   ARG A CG  1 ? 
ATOM   210  C CD  . ARG A 1 29  ? 19.224 21.096 17.036 1.000 32.482  0 29   ARG A CD  1 ? 
ATOM   211  N NE  . ARG A 1 29  ? 18.018 21.645 16.463 1.000 30.955  0 29   ARG A NE  1 ? 
ATOM   212  C CZ  . ARG A 1 29  ? 17.232 20.969 15.664 1.000 30.092  0 29   ARG A CZ  1 ? 
ATOM   213  N NH1 . ARG A 1 29  ? 17.447 19.668 15.569 1.000 28.781  0 29   ARG A NH1 1 ? 
ATOM   214  N NH2 . ARG A 1 29  ? 16.224 21.580 15.043 1.000 27.898  0 29   ARG A NH2 1 ? 
ATOM   215  N N   . GLN A 1 30  ? 18.870 25.406 18.156 1.000 22.478  0 30   GLN A N   1 ? 
ATOM   216  C CA  . GLN A 1 30  ? 17.773 26.187 17.655 1.000 22.036  0 30   GLN A CA  1 ? 
ATOM   217  C C   . GLN A 1 30  ? 16.625 25.282 17.222 1.000 23.839  0 30   GLN A C   1 ? 
ATOM   218  O O   . GLN A 1 30  ? 16.816 24.261 16.574 1.000 24.876  0 30   GLN A O   1 ? 
ATOM   219  C CB  . GLN A 1 30  ? 18.253 27.001 16.461 1.000 25.348  0 30   GLN A CB  1 ? 
ATOM   220  C CG  . GLN A 1 30  ? 17.144 27.885 15.930 1.000 25.232  0 30   GLN A CG  1 ? 
ATOM   221  C CD  . GLN A 1 30  ? 17.640 28.875 14.906 1.000 29.533  0 30   GLN A CD  1 ? 
ATOM   222  O OE1 . GLN A 1 30  ? 18.784 29.305 14.921 1.000 34.273  0 30   GLN A OE1 1 ? 
ATOM   223  N NE2 . GLN A 1 30  ? 16.814 29.134 13.932 1.000 35.402  0 30   GLN A NE2 1 ? 
ATOM   224  N N   . LEU A 1 31  ? 15.415 25.607 17.646 1.000 21.360  0 31   LEU A N   1 ? 
ATOM   225  C CA  . LEU A 1 31  ? 14.226 24.950 17.163 1.000 22.016  0 31   LEU A CA  1 ? 
ATOM   226  C C   . LEU A 1 31  ? 13.322 26.018 16.584 1.000 22.562  0 31   LEU A C   1 ? 
ATOM   227  O O   . LEU A 1 31  ? 12.674 26.776 17.279 1.000 22.178  0 31   LEU A O   1 ? 
ATOM   228  C CB  . LEU A 1 31  ? 13.478 24.248 18.298 1.000 22.898  0 31   LEU A CB  1 ? 
ATOM   229  C CG  . LEU A 1 31  ? 14.115 23.008 18.883 1.000 27.725  0 31   LEU A CG  1 ? 
ATOM   230  C CD1 . LEU A 1 31  ? 13.229 22.490 19.975 1.000 31.865  0 31   LEU A CD1 1 ? 
ATOM   231  C CD2 . LEU A 1 31  ? 14.246 21.956 17.820 1.000 33.777  0 31   LEU A CD2 1 ? 
ATOM   232  N N   . ASN A 1 32  ? 13.176 26.021 15.264 1.000 22.170  0 32   ASN A N   1 ? 
ATOM   233  C CA  . ASN A 1 32  ? 12.156 26.846 14.679 1.000 23.121  0 32   ASN A CA  1 ? 
ATOM   234  C C   . ASN A 1 32  ? 10.814 26.241 15.019 1.000 22.425  0 32   ASN A C   1 ? 
ATOM   235  O O   . ASN A 1 32  ? 10.713 25.114 15.489 1.000 22.129  0 32   ASN A O   1 ? 
ATOM   236  C CB  . ASN A 1 32  ? 12.314 26.902 13.162 1.000 26.446  0 32   ASN A CB  1 ? 
ATOM   237  C CG  . ASN A 1 32  ? 13.640 27.517 12.798 1.000 31.533  0 32   ASN A CG  1 ? 
ATOM   238  O OD1 . ASN A 1 32  ? 14.286 27.102 11.855 1.000 42.320  0 32   ASN A OD1 1 ? 
ATOM   239  N ND2 . ASN A 1 32  ? 14.025 28.545 13.490 1.000 29.659  0 32   ASN A ND2 1 ? 
ATOM   240  N N   . SER A 1 33  ? 9.763  27.022 14.766 1.000 21.000  0 33   SER A N   1 ? 
ATOM   241  C CA  . SER A 1 33  ? 8.412  26.607 15.006 1.000 20.525  0 33   SER A CA  1 ? 
ATOM   242  C C   . SER A 1 33  ? 8.154  25.298 14.288 1.000 20.052  0 33   SER A C   1 ? 
ATOM   243  O O   . SER A 1 33  ? 8.254  25.212 13.044 1.000 21.207  0 33   SER A O   1 ? 
ATOM   244  C CB  . SER A 1 33  ? 7.425  27.660 14.562 1.000 25.070  0 33   SER A CB  1 ? 
ATOM   245  O OG  . SER A 1 33  ? 6.119  27.195 14.732 1.000 23.107  0 33   SER A OG  1 ? 
ATOM   246  N N   . GLY A 1 34  ? 7.758  24.318 15.080 1.000 21.154  0 34   GLY A N   1 ? 
ATOM   247  C CA  . GLY A 1 34  ? 7.445  22.995 14.584 1.000 20.044  0 34   GLY A CA  1 ? 
ATOM   248  C C   . GLY A 1 34  ? 8.584  21.967 14.623 1.000 20.871  0 34   GLY A C   1 ? 
ATOM   249  O O   . GLY A 1 34  ? 8.331  20.766 14.432 1.000 22.671  0 34   GLY A O   1 ? 
ATOM   250  N N   . GLU A 1 35  ? 9.812  22.405 14.843 1.000 20.558  0 35   GLU A N   1 ? 
ATOM   251  C CA  . GLU A 1 35  ? 10.952 21.521 14.795 1.000 21.715  0 35   GLU A CA  1 ? 
ATOM   252  C C   . GLU A 1 35  ? 11.002 20.680 16.067 1.000 21.668  0 35   GLU A C   1 ? 
ATOM   253  O O   . GLU A 1 35  ? 10.548 21.067 17.134 1.000 23.220  0 35   GLU A O   1 ? 
ATOM   254  C CB  . GLU A 1 35  ? 12.240 22.302 14.615 1.000 20.802  0 35   GLU A CB  1 ? 
ATOM   255  C CG  . GLU A 1 35  ? 12.400 22.860 13.211 1.000 21.760  0 35   GLU A CG  1 ? 
ATOM   256  C CD  . GLU A 1 35  ? 13.729 23.460 12.913 1.000 27.216  0 35   GLU A CD  1 ? 
ATOM   257  O OE1 . GLU A 1 35  ? 14.390 23.916 13.837 1.000 25.539  0 35   GLU A OE1 1 ? 
ATOM   258  O OE2 . GLU A 1 35  ? 14.156 23.346 11.767 1.000 29.042  0 35   GLU A OE2 1 ? 
ATOM   259  N N   . SER A 1 36  ? 11.557 19.498 15.899 1.000 21.117  0 36   SER A N   1 ? 
ATOM   260  C CA  . SER A 1 36  ? 11.724 18.518 16.957 1.000 23.315  0 36   SER A CA  1 ? 
ATOM   261  C C   . SER A 1 36  ? 13.199 18.167 17.015 1.000 25.458  0 36   SER A C   1 ? 
ATOM   262  O O   . SER A 1 36  ? 13.867 18.048 16.001 1.000 26.030  0 36   SER A O   1 ? 
ATOM   263  C CB  . SER A 1 36  ? 10.907 17.280 16.619 1.000 22.576  0 36   SER A CB  1 ? 
ATOM   264  O OG  . SER A 1 36  ? 9.538  17.614 16.469 1.000 25.718  0 36   SER A OG  1 ? 
ATOM   265  N N   . TRP A 1 37  ? 13.697 17.952 18.222 1.000 22.975  0 37   TRP A N   1 ? 
ATOM   266  C CA  . TRP A 1 37  ? 15.097 17.667 18.450 1.000 22.662  0 37   TRP A CA  1 ? 
ATOM   267  C C   . TRP A 1 37  ? 15.095 16.466 19.361 1.000 24.798  0 37   TRP A C   1 ? 
ATOM   268  O O   . TRP A 1 37  ? 14.502 16.509 20.405 1.000 24.591  0 37   TRP A O   1 ? 
ATOM   269  C CB  . TRP A 1 37  ? 15.782 18.843 19.116 1.000 24.882  0 37   TRP A CB  1 ? 
ATOM   270  C CG  . TRP A 1 37  ? 17.205 18.638 19.511 1.000 28.545  0 37   TRP A CG  1 ? 
ATOM   271  C CD1 . TRP A 1 37  ? 18.153 17.919 18.861 1.000 31.796  0 37   TRP A CD1 1 ? 
ATOM   272  C CD2 . TRP A 1 37  ? 17.862 19.264 20.638 1.000 27.125  0 37   TRP A CD2 1 ? 
ATOM   273  N NE1 . TRP A 1 37  ? 19.349 18.058 19.521 1.000 32.019  0 37   TRP A NE1 1 ? 
ATOM   274  C CE2 . TRP A 1 37  ? 19.209 18.858 20.605 1.000 29.907  0 37   TRP A CE2 1 ? 
ATOM   275  C CE3 . TRP A 1 37  ? 17.420 20.067 21.677 1.000 25.665  0 37   TRP A CE3 1 ? 
ATOM   276  C CZ2 . TRP A 1 37  ? 20.116 19.245 21.589 1.000 28.460  0 37   TRP A CZ2 1 ? 
ATOM   277  C CZ3 . TRP A 1 37  ? 18.311 20.478 22.643 1.000 32.608  0 37   TRP A CZ3 1 ? 
ATOM   278  C CH2 . TRP A 1 37  ? 19.641 20.054 22.599 1.000 30.012  0 37   TRP A CH2 1 ? 
ATOM   279  N N   . THR A 1 38  ? 15.714 15.378 18.929 1.000 26.699  0 38   THR A N   1 ? 
ATOM   280  C CA  . THR A 1 38  ? 15.751 14.200 19.754 1.000 26.357  0 38   THR A CA  1 ? 
ATOM   281  C C   . THR A 1 38  ? 17.132 14.105 20.385 1.000 24.441  0 38   THR A C   1 ? 
ATOM   282  O O   . THR A 1 38  ? 18.143 14.276 19.680 1.000 29.106  0 38   THR A O   1 ? 
ATOM   283  C CB  . THR A 1 38  ? 15.465 12.977 18.877 1.000 32.880  0 38   THR A CB  1 ? 
ATOM   284  O OG1 . THR A 1 38  ? 14.115 13.090 18.442 1.000 32.469  0 38   THR A OG1 1 ? 
ATOM   285  C CG2 . THR A 1 38  ? 15.626 11.685 19.633 1.000 37.429  0 38   THR A CG2 1 ? 
ATOM   286  N N   . ILE A 1 39  ? 17.132 13.996 21.692 1.000 26.097  0 39   ILE A N   1 ? 
ATOM   287  C CA  . ILE A 1 39  ? 18.372 13.869 22.417 1.000 26.850  0 39   ILE A CA  1 ? 
ATOM   288  C C   . ILE A 1 39  ? 18.346 12.563 23.173 1.000 28.533  0 39   ILE A C   1 ? 
ATOM   289  O O   . ILE A 1 39  ? 17.306 12.055 23.561 1.000 27.478  0 39   ILE A O   1 ? 
ATOM   290  C CB  . ILE A 1 39  ? 18.670 15.060 23.338 1.000 26.642  0 39   ILE A CB  1 ? 
ATOM   291  C CG1 . ILE A 1 39  ? 17.699 15.157 24.498 1.000 26.693  0 39   ILE A CG1 1 ? 
ATOM   292  C CG2 . ILE A 1 39  ? 18.752 16.334 22.506 1.000 33.127  0 39   ILE A CG2 1 ? 
ATOM   293  C CD1 . ILE A 1 39  ? 18.084 16.223 25.538 1.000 30.793  0 39   ILE A CD1 1 ? 
ATOM   294  N N   . ASN A 1 40  ? 19.559 12.097 23.458 1.000 29.933  0 40   ASN A N   1 ? 
ATOM   295  C CA  A ASN A 1 40  ? 19.721 10.937 24.303 0.500 28.739  0 40   ASN A CA  1 ? 
ATOM   296  C CA  B ASN A 1 40  ? 19.761 10.937 24.288 0.500 29.322  0 40   ASN A CA  1 ? 
ATOM   297  C C   . ASN A 1 40  ? 20.382 11.401 25.595 1.000 28.226  0 40   ASN A C   1 ? 
ATOM   298  O O   . ASN A 1 40  ? 21.375 12.148 25.596 1.000 32.109  0 40   ASN A O   1 ? 
ATOM   299  C CB  A ASN A 1 40  ? 20.467 9.807  23.572 0.500 36.158  0 40   ASN A CB  1 ? 
ATOM   300  C CB  B ASN A 1 40  ? 20.673 9.915  23.600 0.500 36.145  0 40   ASN A CB  1 ? 
ATOM   301  C CG  A ASN A 1 40  ? 19.672 9.202  22.428 0.500 35.437  0 40   ASN A CG  1 ? 
ATOM   302  C CG  B ASN A 1 40  ? 20.758 8.624  24.390 0.500 39.172  0 40   ASN A CG  1 ? 
ATOM   303  O OD1 A ASN A 1 40  ? 18.653 8.522  22.602 0.500 40.319  0 40   ASN A OD1 1 ? 
ATOM   304  O OD1 B ASN A 1 40  ? 19.793 7.861  24.478 0.500 39.296  0 40   ASN A OD1 1 ? 
ATOM   305  N ND2 A ASN A 1 40  ? 20.087 9.536  21.226 0.500 38.304  0 40   ASN A ND2 1 ? 
ATOM   306  N ND2 B ASN A 1 40  ? 21.894 8.416  25.018 0.500 40.336  0 40   ASN A ND2 1 ? 
ATOM   307  N N   . VAL A 1 41  ? 19.778 10.966 26.675 1.000 27.986  0 41   VAL A N   1 ? 
ATOM   308  C CA  . VAL A 1 41  ? 20.212 11.270 28.013 1.000 28.415  0 41   VAL A CA  1 ? 
ATOM   309  C C   . VAL A 1 41  ? 20.649 9.969  28.677 1.000 28.450  0 41   VAL A C   1 ? 
ATOM   310  O O   . VAL A 1 41  ? 19.910 9.008  28.692 1.000 31.757  0 41   VAL A O   1 ? 
ATOM   311  C CB  . VAL A 1 41  ? 19.101 11.967 28.791 1.000 29.512  0 41   VAL A CB  1 ? 
ATOM   312  C CG1 . VAL A 1 41  ? 19.535 12.207 30.212 1.000 33.943  0 41   VAL A CG1 1 ? 
ATOM   313  C CG2 . VAL A 1 41  ? 18.739 13.302 28.104 1.000 30.005  0 41   VAL A CG2 1 ? 
ATOM   314  N N   . GLU A 1 42  ? 21.870 10.005 29.196 1.000 33.269  0 42   GLU A N   1 ? 
ATOM   315  C CA  . GLU A 1 42  ? 22.448 8.824  29.819 1.000 31.211  0 42   GLU A CA  1 ? 
ATOM   316  C C   . GLU A 1 42  ? 21.559 8.354  30.959 1.000 30.716  0 42   GLU A C   1 ? 
ATOM   317  O O   . GLU A 1 42  ? 21.131 9.129  31.818 1.000 31.580  0 42   GLU A O   1 ? 
ATOM   318  C CB  . GLU A 1 42  ? 23.833 9.167  30.353 1.000 38.455  0 42   GLU A CB  1 ? 
ATOM   319  C CG  . GLU A 1 42  ? 24.988 8.663  29.506 1.000 60.643  0 42   GLU A CG  1 ? 
ATOM   320  C CD  . GLU A 1 42  ? 25.927 7.833  30.383 1.000 77.837  0 42   GLU A CD  1 ? 
ATOM   321  O OE1 . GLU A 1 42  ? 26.317 8.318  31.485 1.000 73.428  0 42   GLU A OE1 1 ? 
ATOM   322  O OE2 . GLU A 1 42  ? 26.219 6.672  30.013 1.000 82.020  0 42   GLU A OE2 1 ? 
ATOM   323  N N   . PRO A 1 43  ? 21.281 7.046  31.063 1.000 28.952  0 43   PRO A N   1 ? 
ATOM   324  C CA  . PRO A 1 43  ? 20.632 6.503  32.250 1.000 29.010  0 43   PRO A CA  1 ? 
ATOM   325  C C   . PRO A 1 43  ? 21.387 6.908  33.513 1.000 30.428  0 43   PRO A C   1 ? 
ATOM   326  O O   . PRO A 1 43  ? 22.589 7.153  33.506 1.000 31.481  0 43   PRO A O   1 ? 
ATOM   327  C CB  . PRO A 1 43  ? 20.701 4.972  32.045 1.000 32.024  0 43   PRO A CB  1 ? 
ATOM   328  C CG  . PRO A 1 43  ? 20.967 4.796  30.578 1.000 34.811  0 43   PRO A CG  1 ? 
ATOM   329  C CD  . PRO A 1 43  ? 21.748 6.011  30.127 1.000 33.280  0 43   PRO A CD  1 ? 
ATOM   330  N N   . GLY A 1 44  ? 20.609 7.079  34.581 1.000 30.530  0 44   GLY A N   1 ? 
ATOM   331  C CA  . GLY A 1 44  ? 21.131 7.466  35.869 1.000 33.431  0 44   GLY A CA  1 ? 
ATOM   332  C C   . GLY A 1 44  ? 21.389 8.950  36.000 1.000 36.644  0 44   GLY A C   1 ? 
ATOM   333  O O   . GLY A 1 44  ? 21.863 9.381  37.042 1.000 35.394  0 44   GLY A O   1 ? 
ATOM   334  N N   . THR A 1 45  ? 21.083 9.723  34.951 1.000 31.134  0 45   THR A N   1 ? 
ATOM   335  C CA  . THR A 1 45  ? 21.280 11.150 35.025 1.000 32.670  0 45   THR A CA  1 ? 
ATOM   336  C C   . THR A 1 45  ? 20.366 11.679 36.131 1.000 27.716  0 45   THR A C   1 ? 
ATOM   337  O O   . THR A 1 45  ? 19.164 11.409 36.183 1.000 30.625  0 45   THR A O   1 ? 
ATOM   338  C CB  . THR A 1 45  ? 20.996 11.836 33.694 1.000 30.575  0 45   THR A CB  1 ? 
ATOM   339  O OG1 . THR A 1 45  ? 21.926 11.424 32.697 1.000 32.377  0 45   THR A OG1 1 ? 
ATOM   340  C CG2 . THR A 1 45  ? 21.085 13.343 33.818 1.000 33.169  0 45   THR A CG2 1 ? 
ATOM   341  N N   . LYS A 1 46  ? 20.972 12.456 37.022 1.000 29.850  0 46   LYS A N   1 ? 
ATOM   342  C CA  . LYS A 1 46  ? 20.308 12.974 38.202 1.000 30.495  0 46   LYS A CA  1 ? 
ATOM   343  C C   . LYS A 1 46  ? 20.355 14.493 38.079 1.000 30.432  0 46   LYS A C   1 ? 
ATOM   344  O O   . LYS A 1 46  ? 21.404 15.032 37.793 1.000 31.128  0 46   LYS A O   1 ? 
ATOM   345  C CB  . LYS A 1 46  ? 21.067 12.542 39.460 1.000 37.142  0 46   LYS A CB  1 ? 
ATOM   346  C CG  . LYS A 1 46  ? 20.585 13.197 40.739 1.000 51.410  0 46   LYS A CG  1 ? 
ATOM   347  C CD  . LYS A 1 46  ? 19.704 12.277 41.533 1.000 73.057  0 46   LYS A CD  1 ? 
ATOM   348  C CE  . LYS A 1 46  ? 19.394 12.792 42.927 1.000 89.948  0 46   LYS A CE  1 ? 
ATOM   349  N NZ  . LYS A 1 46  ? 18.372 13.864 42.877 1.000 94.943  0 46   LYS A NZ  1 ? 
ATOM   350  N N   . GLY A 1 47  ? 19.220 15.169 38.213 1.000 28.551  0 47   GLY A N   1 ? 
ATOM   351  C CA  . GLY A 1 47  ? 19.259 16.630 38.206 1.000 29.580  0 47   GLY A CA  1 ? 
ATOM   352  C C   . GLY A 1 47  ? 19.396 17.226 36.800 1.000 29.684  0 47   GLY A C   1 ? 
ATOM   353  O O   . GLY A 1 47  ? 19.970 18.299 36.640 1.000 29.816  0 47   GLY A O   1 ? 
ATOM   354  N N   . GLY A 1 48  ? 18.832 16.555 35.781 1.000 23.899  0 48   GLY A N   1 ? 
ATOM   355  C CA  . GLY A 1 48  ? 18.789 17.114 34.443 1.000 21.683  0 48   GLY A CA  1 ? 
ATOM   356  C C   . GLY A 1 48  ? 17.672 18.132 34.303 1.000 23.397  0 48   GLY A C   1 ? 
ATOM   357  O O   . GLY A 1 48  ? 16.678 18.059 35.004 1.000 24.672  0 48   GLY A O   1 ? 
ATOM   358  N N   . LYS A 1 49  ? 17.919 19.112 33.437 1.000 22.294  0 49   LYS A N   1 ? 
ATOM   359  C CA  . LYS A 1 49  ? 16.890 20.085 33.143 1.000 21.740  0 49   LYS A CA  1 ? 
ATOM   360  C C   . LYS A 1 49  ? 16.887 20.358 31.652 1.000 20.079  0 49   LYS A C   1 ? 
ATOM   361  O O   . LYS A 1 49  ? 17.942 20.413 30.996 1.000 22.987  0 49   LYS A O   1 ? 
ATOM   362  C CB  . LYS A 1 49  ? 17.159 21.361 33.916 1.000 23.329  0 49   LYS A CB  1 ? 
ATOM   363  C CG  . LYS A 1 49  ? 17.293 21.167 35.410 1.000 25.025  0 49   LYS A CG  1 ? 
ATOM   364  C CD  . LYS A 1 49  ? 17.194 22.441 36.211 1.000 27.267  0 49   LYS A CD  1 ? 
ATOM   365  C CE  . LYS A 1 49  ? 17.682 22.321 37.636 1.000 32.198  0 49   LYS A CE  1 ? 
ATOM   366  N NZ  . LYS A 1 49  ? 16.793 21.476 38.434 1.000 36.171  0 49   LYS A NZ  1 ? 
ATOM   367  N N   . ILE A 1 50  ? 15.683 20.617 31.165 1.000 20.566  0 50   ILE A N   1 ? 
ATOM   368  C CA  . ILE A 1 50  ? 15.499 21.126 29.830 1.000 19.290  0 50   ILE A CA  1 ? 
ATOM   369  C C   . ILE A 1 50  ? 14.704 22.414 29.957 1.000 18.168  0 50   ILE A C   1 ? 
ATOM   370  O O   . ILE A 1 50  ? 13.759 22.485 30.742 1.000 22.106  0 50   ILE A O   1 ? 
ATOM   371  C CB  . ILE A 1 50  ? 14.783 20.051 28.995 1.000 21.915  0 50   ILE A CB  1 ? 
ATOM   372  C CG1 . ILE A 1 50  ? 15.781 18.926 28.699 1.000 22.796  0 50   ILE A CG1 1 ? 
ATOM   373  C CG2 . ILE A 1 50  ? 14.151 20.605 27.747 1.000 22.830  0 50   ILE A CG2 1 ? 
ATOM   374  C CD1 . ILE A 1 50  ? 15.135 17.645 28.181 1.000 27.352  0 50   ILE A CD1 1 ? 
ATOM   375  N N   . TRP A 1 51  ? 15.080 23.374 29.125 1.000 20.205  0 51   TRP A N   1 ? 
ATOM   376  C CA  . TRP A 1 51  ? 14.359 24.626 29.091 1.000 19.861  0 51   TRP A CA  1 ? 
ATOM   377  C C   . TRP A 1 51  ? 14.500 25.201 27.694 1.000 20.804  0 51   TRP A C   1 ? 
ATOM   378  O O   . TRP A 1 51  ? 15.312 24.733 26.883 1.000 21.115  0 51   TRP A O   1 ? 
ATOM   379  C CB  . TRP A 1 51  ? 14.894 25.553 30.178 1.000 21.125  0 51   TRP A CB  1 ? 
ATOM   380  C CG  . TRP A 1 51  ? 16.277 26.081 30.015 1.000 20.145  0 51   TRP A CG  1 ? 
ATOM   381  C CD1 . TRP A 1 51  ? 16.642 27.332 29.603 1.000 20.506  0 51   TRP A CD1 1 ? 
ATOM   382  C CD2 . TRP A 1 51  ? 17.503 25.404 30.340 1.000 21.376  0 51   TRP A CD2 1 ? 
ATOM   383  N NE1 . TRP A 1 51  ? 17.991 27.470 29.627 1.000 22.198  0 51   TRP A NE1 1 ? 
ATOM   384  C CE2 . TRP A 1 51  ? 18.541 26.303 30.079 1.000 21.900  0 51   TRP A CE2 1 ? 
ATOM   385  C CE3 . TRP A 1 51  ? 17.810 24.127 30.823 1.000 24.031  0 51   TRP A CE3 1 ? 
ATOM   386  C CZ2 . TRP A 1 51  ? 19.876 25.968 30.237 1.000 24.972  0 51   TRP A CZ2 1 ? 
ATOM   387  C CZ3 . TRP A 1 51  ? 19.140 23.797 30.958 1.000 23.761  0 51   TRP A CZ3 1 ? 
ATOM   388  C CH2 . TRP A 1 51  ? 20.142 24.723 30.741 1.000 23.876  0 51   TRP A CH2 1 ? 
ATOM   389  N N   . ALA A 1 52  ? 13.715 26.246 27.469 1.000 20.853  0 52   ALA A N   1 ? 
ATOM   390  C CA  . ALA A 1 52  ? 13.773 27.023 26.271 1.000 19.349  0 52   ALA A CA  1 ? 
ATOM   391  C C   . ALA A 1 52  ? 14.390 28.374 26.618 1.000 19.428  0 52   ALA A C   1 ? 
ATOM   392  O O   . ALA A 1 52  ? 14.230 28.898 27.703 1.000 21.693  0 52   ALA A O   1 ? 
ATOM   393  C CB  . ALA A 1 52  ? 12.385 27.215 25.715 1.000 21.677  0 52   ALA A CB  1 ? 
ATOM   394  N N   . ARG A 1 53  ? 15.099 28.865 25.645 1.000 19.006  0 53   ARG A N   1 ? 
ATOM   395  C CA  . ARG A 1 53  ? 15.649 30.209 25.627 1.000 19.894  0 53   ARG A CA  1 ? 
ATOM   396  C C   . ARG A 1 53  ? 14.960 30.972 24.537 1.000 21.071  0 53   ARG A C   1 ? 
ATOM   397  O O   . ARG A 1 53  ? 14.719 30.444 23.464 1.000 22.354  0 53   ARG A O   1 ? 
ATOM   398  C CB  . ARG A 1 53  ? 17.141 30.108 25.439 1.000 21.094  0 53   ARG A CB  1 ? 
ATOM   399  C CG  . ARG A 1 53  ? 17.813 29.347 26.545 1.000 20.542  0 53   ARG A CG  1 ? 
ATOM   400  C CD  . ARG A 1 53  ? 19.236 29.070 26.169 1.000 22.241  0 53   ARG A CD  1 ? 
ATOM   401  N NE  . ARG A 1 53  ? 19.315 28.113 25.074 1.000 21.451  0 53   ARG A NE  1 ? 
ATOM   402  C CZ  . ARG A 1 53  ? 20.458 27.767 24.502 1.000 23.681  0 53   ARG A CZ  1 ? 
ATOM   403  N NH1 . ARG A 1 53  ? 21.552 28.451 24.793 1.000 25.559  0 53   ARG A NH1 1 ? 
ATOM   404  N NH2 . ARG A 1 53  ? 20.507 26.723 23.683 1.000 24.837  0 53   ARG A NH2 1 ? 
ATOM   405  N N   . THR A 1 54  ? 14.705 32.255 24.805 1.000 20.761  0 54   THR A N   1 ? 
ATOM   406  C CA  . THR A 1 54  ? 14.085 33.115 23.829 1.000 20.621  0 54   THR A CA  1 ? 
ATOM   407  C C   . THR A 1 54  ? 15.001 34.237 23.423 1.000 24.264  0 54   THR A C   1 ? 
ATOM   408  O O   . THR A 1 54  ? 15.852 34.639 24.192 1.000 22.059  0 54   THR A O   1 ? 
ATOM   409  C CB  . THR A 1 54  ? 12.761 33.671 24.301 1.000 23.790  0 54   THR A CB  1 ? 
ATOM   410  O OG1 . THR A 1 54  ? 13.021 34.370 25.525 1.000 23.107  0 54   THR A OG1 1 ? 
ATOM   411  C CG2 . THR A 1 54  ? 11.761 32.560 24.548 1.000 25.528  0 54   THR A CG2 1 ? 
ATOM   412  N N   . ASP A 1 55  ? 14.769 34.682 22.193 1.000 23.031  0 55   ASP A N   1 ? 
ATOM   413  C CA  . ASP A 1 55  ? 15.439 35.848 21.630 1.000 25.441  0 55   ASP A CA  1 ? 
ATOM   414  C C   . ASP A 1 55  ? 16.934 35.755 21.794 1.000 27.910  0 55   ASP A C   1 ? 
ATOM   415  O O   . ASP A 1 55  ? 17.538 36.604 22.410 1.000 26.386  0 55   ASP A O   1 ? 
ATOM   416  C CB  . ASP A 1 55  ? 14.940 37.139 22.263 1.000 27.636  0 55   ASP A CB  1 ? 
ATOM   417  C CG  . ASP A 1 55  ? 13.502 37.417 21.921 1.000 35.753  0 55   ASP A CG  1 ? 
ATOM   418  O OD1 . ASP A 1 55  ? 13.196 37.452 20.759 1.000 46.982  0 55   ASP A OD1 1 ? 
ATOM   419  O OD2 . ASP A 1 55  ? 12.715 37.477 22.829 1.000 41.619  0 55   ASP A OD2 1 ? 
ATOM   420  N N   . CYS A 1 56  ? 17.503 34.744 21.155 1.000 24.557  0 56   CYS A N   1 ? 
ATOM   421  C CA  . CYS A 1 56  ? 18.930 34.543 21.189 1.000 24.577  0 56   CYS A CA  1 ? 
ATOM   422  C C   . CYS A 1 56  ? 19.570 35.042 19.900 1.000 28.186  0 56   CYS A C   1 ? 
ATOM   423  O O   . CYS A 1 56  ? 18.948 34.990 18.834 1.000 30.266  0 56   CYS A O   1 ? 
ATOM   424  C CB  . CYS A 1 56  ? 19.270 33.070 21.253 1.000 23.892  0 56   CYS A CB  1 ? 
ATOM   425  S SG  . CYS A 1 56  ? 18.525 32.246 22.666 1.000 24.248  0 56   CYS A SG  1 ? 
ATOM   426  N N   . TYR A 1 57  ? 20.830 35.429 20.043 1.000 28.335  0 57   TYR A N   1 ? 
ATOM   427  C CA  . TYR A 1 57  ? 21.734 35.726 18.939 1.000 33.325  0 57   TYR A CA  1 ? 
ATOM   428  C C   . TYR A 1 57  ? 23.009 34.960 19.219 1.000 32.063  0 57   TYR A C   1 ? 
ATOM   429  O O   . TYR A 1 57  ? 23.645 35.172 20.244 1.000 36.339  0 57   TYR A O   1 ? 
ATOM   430  C CB  . TYR A 1 57  ? 21.963 37.244 18.819 1.000 33.835  0 57   TYR A CB  1 ? 
ATOM   431  C CG  . TYR A 1 57  ? 20.683 37.995 18.514 1.000 47.007  0 57   TYR A CG  1 ? 
ATOM   432  C CD1 . TYR A 1 57  ? 19.826 38.393 19.537 1.000 47.669  0 57   TYR A CD1 1 ? 
ATOM   433  C CD2 . TYR A 1 57  ? 20.226 38.180 17.200 1.000 58.020  0 57   TYR A CD2 1 ? 
ATOM   434  C CE1 . TYR A 1 57  ? 18.603 39.004 19.281 1.000 51.549  0 57   TYR A CE1 1 ? 
ATOM   435  C CE2 . TYR A 1 57  ? 19.014 38.816 16.928 1.000 46.188  0 57   TYR A CE2 1 ? 
ATOM   436  C CZ  . TYR A 1 57  ? 18.196 39.217 17.970 1.000 55.792  0 57   TYR A CZ  1 ? 
ATOM   437  O OH  . TYR A 1 57  ? 16.972 39.818 17.783 1.000 63.572  0 57   TYR A OH  1 ? 
ATOM   438  N N   . PHE A 1 58  ? 23.424 34.141 18.257 1.000 30.808  0 58   PHE A N   1 ? 
ATOM   439  C CA  . PHE A 1 58  ? 24.677 33.427 18.336 1.000 33.646  0 58   PHE A CA  1 ? 
ATOM   440  C C   . PHE A 1 58  ? 25.484 33.669 17.059 1.000 36.729  0 58   PHE A C   1 ? 
ATOM   441  O O   . PHE A 1 58  ? 24.910 33.789 15.994 1.000 39.399  0 58   PHE A O   1 ? 
ATOM   442  C CB  . PHE A 1 58  ? 24.389 31.943 18.507 1.000 32.288  0 58   PHE A CB  1 ? 
ATOM   443  C CG  . PHE A 1 58  ? 23.709 31.625 19.807 1.000 30.213  0 58   PHE A CG  1 ? 
ATOM   444  C CD1 . PHE A 1 58  ? 24.407 31.711 20.998 1.000 30.436  0 58   PHE A CD1 1 ? 
ATOM   445  C CD2 . PHE A 1 58  ? 22.382 31.246 19.829 1.000 28.457  0 58   PHE A CD2 1 ? 
ATOM   446  C CE1 . PHE A 1 58  ? 23.796 31.403 22.198 1.000 31.097  0 58   PHE A CE1 1 ? 
ATOM   447  C CE2 . PHE A 1 58  ? 21.781 30.937 21.023 1.000 28.030  0 58   PHE A CE2 1 ? 
ATOM   448  C CZ  . PHE A 1 58  ? 22.483 31.016 22.209 1.000 28.578  0 58   PHE A CZ  1 ? 
ATOM   449  N N   . ASP A 1 59  ? 26.786 33.778 17.217 1.000 41.896  0 59   ASP A N   1 ? 
ATOM   450  C CA  . ASP A 1 59  ? 27.681 33.884 16.076 1.000 42.273  0 59   ASP A CA  1 ? 
ATOM   451  C C   . ASP A 1 59  ? 27.936 32.476 15.543 1.000 48.406  0 59   ASP A C   1 ? 
ATOM   452  O O   . ASP A 1 59  ? 27.355 31.516 16.032 1.000 42.013  0 59   ASP A O   1 ? 
ATOM   453  C CB  . ASP A 1 59  ? 28.928 34.659 16.495 1.000 43.455  0 59   ASP A CB  1 ? 
ATOM   454  C CG  . ASP A 1 59  ? 29.856 33.969 17.468 1.000 45.346  0 59   ASP A CG  1 ? 
ATOM   455  O OD1 . ASP A 1 59  ? 29.719 32.736 17.703 1.000 45.981  0 59   ASP A OD1 1 ? 
ATOM   456  O OD2 . ASP A 1 59  ? 30.711 34.678 18.002 1.000 56.595  0 59   ASP A OD2 1 ? 
ATOM   457  N N   . ASP A 1 60  ? 28.838 32.342 14.559 1.000 55.174  0 60   ASP A N   1 ? 
ATOM   458  C CA  . ASP A 1 60  ? 29.176 31.035 14.013 1.000 62.115  0 60   ASP A CA  1 ? 
ATOM   459  C C   . ASP A 1 60  ? 29.883 30.150 15.039 1.000 49.254  0 60   ASP A C   1 ? 
ATOM   460  O O   . ASP A 1 60  ? 29.772 28.937 14.942 1.000 59.431  0 60   ASP A O   1 ? 
ATOM   461  C CB  . ASP A 1 60  ? 30.024 31.170 12.746 1.000 70.584  0 60   ASP A CB  1 ? 
ATOM   462  C CG  . ASP A 1 60  ? 29.350 32.092 11.749 1.000 77.119  0 60   ASP A CG  1 ? 
ATOM   463  O OD1 . ASP A 1 60  ? 28.183 31.811 11.374 1.000 75.401  0 60   ASP A OD1 1 ? 
ATOM   464  O OD2 . ASP A 1 60  ? 29.965 33.115 11.410 1.000 88.535  0 60   ASP A OD2 1 ? 
ATOM   465  N N   . SER A 1 61  ? 30.588 30.721 16.031 1.000 49.949  0 61   SER A N   1 ? 
ATOM   466  C CA  . SER A 1 61  ? 31.219 29.896 17.061 1.000 52.596  0 61   SER A CA  1 ? 
ATOM   467  C C   . SER A 1 61  ? 30.221 29.363 18.110 1.000 52.398  0 61   SER A C   1 ? 
ATOM   468  O O   . SER A 1 61  ? 30.623 28.639 19.006 1.000 46.300  0 61   SER A O   1 ? 
ATOM   469  C CB  . SER A 1 61  ? 32.360 30.636 17.728 1.000 58.310  0 61   SER A CB  1 ? 
ATOM   470  O OG  . SER A 1 61  ? 31.885 31.669 18.588 1.000 66.240  0 61   SER A OG  1 ? 
ATOM   471  N N   . GLY A 1 62  ? 28.931 29.736 18.056 1.000 45.783  0 62   GLY A N   1 ? 
ATOM   472  C CA  . GLY A 1 62  ? 27.977 29.272 19.061 1.000 45.109  0 62   GLY A CA  1 ? 
ATOM   473  C C   . GLY A 1 62  ? 28.019 30.094 20.350 1.000 38.927  0 62   GLY A C   1 ? 
ATOM   474  O O   . GLY A 1 62  ? 27.684 29.598 21.421 1.000 37.009  0 62   GLY A O   1 ? 
ATOM   475  N N   . SER A 1 63  ? 28.428 31.357 20.221 1.000 37.123  0 63   SER A N   1 ? 
ATOM   476  C CA  A SER A 1 63  ? 28.548 32.265 21.343 0.700 37.770  0 63   SER A CA  1 ? 
ATOM   477  C CA  B SER A 1 63  ? 28.551 32.265 21.347 0.300 35.111  0 63   SER A CA  1 ? 
ATOM   478  C C   . SER A 1 63  ? 27.612 33.444 21.114 1.000 34.434  0 63   SER A C   1 ? 
ATOM   479  O O   . SER A 1 63  ? 27.437 33.902 19.995 1.000 36.052  0 63   SER A O   1 ? 
ATOM   480  C CB  A SER A 1 63  ? 29.971 32.720 21.493 0.700 42.555  0 63   SER A CB  1 ? 
ATOM   481  C CB  B SER A 1 63  ? 29.987 32.711 21.535 0.300 35.095  0 63   SER A CB  1 ? 
ATOM   482  O OG  A SER A 1 63  ? 30.156 33.311 22.765 0.700 46.269  0 63   SER A OG  1 ? 
ATOM   483  O OG  B SER A 1 63  ? 30.788 31.660 22.068 0.300 32.480  0 63   SER A OG  1 ? 
ATOM   484  N N   . GLY A 1 64  ? 26.968 33.933 22.178 1.000 33.232  0 64   GLY A N   1 ? 
ATOM   485  C CA  . GLY A 1 64  ? 26.009 34.987 21.973 1.000 29.210  0 64   GLY A CA  1 ? 
ATOM   486  C C   . GLY A 1 64  ? 25.262 35.286 23.267 1.000 26.910  0 64   GLY A C   1 ? 
ATOM   487  O O   . GLY A 1 64  ? 25.839 35.240 24.341 1.000 27.365  0 64   GLY A O   1 ? 
ATOM   488  N N   . ILE A 1 65  ? 23.974 35.519 23.133 1.000 27.848  0 65   ILE A N   1 ? 
ATOM   489  C CA  . ILE A 1 65  ? 23.168 35.917 24.256 1.000 25.793  0 65   ILE A CA  1 ? 
ATOM   490  C C   . ILE A 1 65  ? 21.712 35.596 23.966 1.000 24.392  0 65   ILE A C   1 ? 
ATOM   491  O O   . ILE A 1 65  ? 21.277 35.688 22.833 1.000 27.691  0 65   ILE A O   1 ? 
ATOM   492  C CB  . ILE A 1 65  ? 23.338 37.416 24.532 1.000 26.921  0 65   ILE A CB  1 ? 
ATOM   493  C CG1 . ILE A 1 65  ? 22.622 37.765 25.833 1.000 32.189  0 65   ILE A CG1 1 ? 
ATOM   494  C CG2 . ILE A 1 65  ? 22.868 38.231 23.331 1.000 31.496  0 65   ILE A CG2 1 ? 
ATOM   495  C CD1 . ILE A 1 65  ? 23.216 38.915 26.541 1.000 40.437  0 65   ILE A CD1 1 ? 
ATOM   496  N N   . CYS A 1 66  ? 20.954 35.307 25.031 1.000 24.080  0 66   CYS A N   1 ? 
ATOM   497  C CA  . CYS A 1 66  ? 19.522 35.116 24.922 1.000 21.987  0 66   CYS A CA  1 ? 
ATOM   498  C C   . CYS A 1 66  ? 18.853 35.964 25.991 1.000 23.803  0 66   CYS A C   1 ? 
ATOM   499  O O   . CYS A 1 66  ? 19.466 36.230 27.007 1.000 25.057  0 66   CYS A O   1 ? 
ATOM   500  C CB  . CYS A 1 66  ? 19.145 33.675 25.240 1.000 23.880  0 66   CYS A CB  1 ? 
ATOM   501  S SG  . CYS A 1 66  ? 19.888 32.453 24.144 1.000 24.353  0 66   CYS A SG  1 ? 
ATOM   502  N N   . LYS A 1 67  ? 17.610 36.393 25.764 1.000 24.776  0 67   LYS A N   1 ? 
ATOM   503  C CA  . LYS A 1 67  ? 16.941 37.236 26.734 1.000 23.500  0 67   LYS A CA  1 ? 
ATOM   504  C C   . LYS A 1 67  ? 16.372 36.421 27.870 1.000 26.072  0 67   LYS A C   1 ? 
ATOM   505  O O   . LYS A 1 67  ? 16.182 36.941 28.963 1.000 27.754  0 67   LYS A O   1 ? 
ATOM   506  C CB  . LYS A 1 67  ? 15.868 38.050 26.030 1.000 25.129  0 67   LYS A CB  1 ? 
ATOM   507  C CG  . LYS A 1 67  ? 16.457 39.074 25.101 1.000 30.392  0 67   LYS A CG  1 ? 
ATOM   508  C CD  . LYS A 1 67  ? 15.560 40.194 24.910 1.000 33.956  0 67   LYS A CD  1 ? 
ATOM   509  C CE  . LYS A 1 67  ? 16.071 41.089 23.817 1.000 37.134  0 67   LYS A CE  1 ? 
ATOM   510  N NZ  . LYS A 1 67  ? 15.068 42.141 23.643 1.000 45.883  0 67   LYS A NZ  1 ? 
ATOM   511  N N   . THR A 1 68  ? 16.096 35.132 27.652 1.000 21.641  0 68   THR A N   1 ? 
ATOM   512  C CA  . THR A 1 68  ? 15.725 34.320 28.792 1.000 21.967  0 68   THR A CA  1 ? 
ATOM   513  C C   . THR A 1 68  ? 16.535 33.046 28.694 1.000 22.908  0 68   THR A C   1 ? 
ATOM   514  O O   . THR A 1 68  ? 16.796 32.589 27.592 1.000 20.933  0 68   THR A O   1 ? 
ATOM   515  C CB  . THR A 1 68  ? 14.232 33.970 28.848 1.000 24.127  0 68   THR A CB  1 ? 
ATOM   516  O OG1 . THR A 1 68  ? 13.796 33.183 27.744 1.000 21.439  0 68   THR A OG1 1 ? 
ATOM   517  C CG2 . THR A 1 68  ? 13.358 35.203 28.932 1.000 23.278  0 68   THR A CG2 1 ? 
ATOM   518  N N   . GLY A 1 69  ? 16.925 32.510 29.847 1.000 22.634  0 69   GLY A N   1 ? 
ATOM   519  C CA  . GLY A 1 69  ? 17.535 31.200 29.940 1.000 22.397  0 69   GLY A CA  1 ? 
ATOM   520  C C   . GLY A 1 69  ? 18.960 31.101 29.414 1.000 20.216  0 69   GLY A C   1 ? 
ATOM   521  O O   . GLY A 1 69  ? 19.434 29.996 29.219 1.000 22.988  0 69   GLY A O   1 ? 
ATOM   522  N N   . ASP A 1 70  ? 19.647 32.226 29.263 1.000 22.604  0 70   ASP A N   1 ? 
ATOM   523  C CA  . ASP A 1 70  ? 21.014 32.248 28.769 1.000 21.715  0 70   ASP A CA  1 ? 
ATOM   524  C C   . ASP A 1 70  ? 21.885 31.404 29.687 1.000 22.717  0 70   ASP A C   1 ? 
ATOM   525  O O   . ASP A 1 70  ? 21.798 31.530 30.915 1.000 24.414  0 70   ASP A O   1 ? 
ATOM   526  C CB  . ASP A 1 70  ? 21.535 33.670 28.701 1.000 22.882  0 70   ASP A CB  1 ? 
ATOM   527  C CG  . ASP A 1 70  ? 22.842 33.773 27.958 1.000 27.537  0 70   ASP A CG  1 ? 
ATOM   528  O OD1 . ASP A 1 70  ? 22.839 33.532 26.772 1.000 32.356  0 70   ASP A OD1 1 ? 
ATOM   529  O OD2 . ASP A 1 70  ? 23.833 33.934 28.646 1.000 33.880  0 70   ASP A OD2 1 ? 
ATOM   530  N N   . CYS A 1 71  ? 22.699 30.527 29.085 1.000 22.970  0 71   CYS A N   1 ? 
ATOM   531  C CA  . CYS A 1 71  ? 23.568 29.648 29.864 1.000 26.852  0 71   CYS A CA  1 ? 
ATOM   532  C C   . CYS A 1 71  ? 25.017 30.061 29.618 1.000 29.651  0 71   CYS A C   1 ? 
ATOM   533  O O   . CYS A 1 71  ? 25.717 29.442 28.830 1.000 29.576  0 71   CYS A O   1 ? 
ATOM   534  C CB  . CYS A 1 71  ? 23.375 28.185 29.502 1.000 25.550  0 71   CYS A CB  1 ? 
ATOM   535  S SG  . CYS A 1 71  ? 23.694 27.883 27.769 1.000 27.117  0 71   CYS A SG  1 ? 
ATOM   536  N N   . GLY A 1 72  ? 25.374 31.237 30.105 1.000 31.757  0 72   GLY A N   1 ? 
ATOM   537  C CA  . GLY A 1 72  ? 26.724 31.753 29.936 1.000 32.267  0 72   GLY A CA  1 ? 
ATOM   538  C C   . GLY A 1 72  ? 27.086 32.100 28.495 1.000 31.049  0 72   GLY A C   1 ? 
ATOM   539  O O   . GLY A 1 72  ? 28.238 31.993 28.088 1.000 31.592  0 72   GLY A O   1 ? 
ATOM   540  N N   . GLY A 1 73  ? 26.115 32.481 27.678 1.000 28.882  0 73   GLY A N   1 ? 
ATOM   541  C CA  . GLY A 1 73  ? 26.408 32.941 26.339 1.000 30.421  0 73   GLY A CA  1 ? 
ATOM   542  C C   . GLY A 1 73  ? 26.607 31.829 25.308 1.000 27.823  0 73   GLY A C   1 ? 
ATOM   543  O O   . GLY A 1 73  ? 27.015 32.122 24.215 1.000 31.617  0 73   GLY A O   1 ? 
ATOM   544  N N   . LEU A 1 74  ? 26.364 30.572 25.644 1.000 26.824  0 74   LEU A N   1 ? 
ATOM   545  C CA  . LEU A 1 74  ? 26.643 29.479 24.720 1.000 29.718  0 74   LEU A CA  1 ? 
ATOM   546  C C   . LEU A 1 74  ? 25.361 28.932 24.091 1.000 26.502  0 74   LEU A C   1 ? 
ATOM   547  O O   . LEU A 1 74  ? 24.324 28.906 24.723 1.000 28.139  0 74   LEU A O   1 ? 
ATOM   548  C CB  . LEU A 1 74  ? 27.328 28.341 25.460 1.000 30.155  0 74   LEU A CB  1 ? 
ATOM   549  C CG  . LEU A 1 74  ? 28.663 28.739 26.092 1.000 38.121  0 74   LEU A CG  1 ? 
ATOM   550  C CD1 . LEU A 1 74  ? 29.286 27.572 26.805 1.000 39.610  0 74   LEU A CD1 1 ? 
ATOM   551  C CD2 . LEU A 1 74  ? 29.593 29.321 25.035 1.000 39.263  0 74   LEU A CD2 1 ? 
ATOM   552  N N   . LEU A 1 75  ? 25.457 28.529 22.846 1.000 27.024  0 75   LEU A N   1 ? 
ATOM   553  C CA  . LEU A 1 75  ? 24.373 27.817 22.197 1.000 28.227  0 75   LEU A CA  1 ? 
ATOM   554  C C   . LEU A 1 75  ? 24.235 26.458 22.861 1.000 28.930  0 75   LEU A C   1 ? 
ATOM   555  O O   . LEU A 1 75  ? 23.167 26.016 23.232 1.000 29.996  0 75   LEU A O   1 ? 
ATOM   556  C CB  . LEU A 1 75  ? 24.699 27.686 20.714 1.000 31.322  0 75   LEU A CB  1 ? 
ATOM   557  C CG  . LEU A 1 75  ? 23.780 26.737 19.957 1.000 34.561  0 75   LEU A CG  1 ? 
ATOM   558  C CD1 . LEU A 1 75  ? 22.360 27.216 20.041 1.000 36.695  0 75   LEU A CD1 1 ? 
ATOM   559  C CD2 . LEU A 1 75  ? 24.207 26.624 18.499 1.000 35.687  0 75   LEU A CD2 1 ? 
ATOM   560  N N   . ARG A 1 76  ? 25.375 25.798 23.083 1.000 29.713  0 76   ARG A N   1 ? 
ATOM   561  C CA  . ARG A 1 76  ? 25.383 24.475 23.645 1.000 31.098  0 76   ARG A CA  1 ? 
ATOM   562  C C   . ARG A 1 76  ? 25.615 24.599 25.130 1.000 33.130  0 76   ARG A C   1 ? 
ATOM   563  O O   . ARG A 1 76  ? 26.736 24.736 25.597 1.000 34.719  0 76   ARG A O   1 ? 
ATOM   564  C CB  . ARG A 1 76  ? 26.450 23.606 22.958 1.000 31.755  0 76   ARG A CB  1 ? 
ATOM   565  C CG  . ARG A 1 76  ? 26.162 23.311 21.490 1.000 38.884  0 76   ARG A CG  1 ? 
ATOM   566  C CD  . ARG A 1 76  ? 27.337 22.553 20.858 1.000 50.878  0 76   ARG A CD  1 ? 
ATOM   567  N NE  . ARG A 1 76  ? 27.353 22.796 19.420 1.000 74.676  0 76   ARG A NE  1 ? 
ATOM   568  C CZ  . ARG A 1 76  ? 27.571 23.986 18.845 1.000 82.680  0 76   ARG A CZ  1 ? 
ATOM   569  N NH1 . ARG A 1 76  ? 28.168 24.973 19.503 1.000 75.288  0 76   ARG A NH1 1 ? 
ATOM   570  N NH2 . ARG A 1 76  ? 27.220 24.171 17.584 1.000 87.287  0 76   ARG A NH2 1 ? 
ATOM   571  N N   . CYS A 1 77  ? 24.538 24.582 25.906 1.000 28.363  0 77   CYS A N   1 ? 
ATOM   572  C CA  . CYS A 1 77  ? 24.662 24.854 27.318 1.000 25.588  0 77   CYS A CA  1 ? 
ATOM   573  C C   . CYS A 1 77  ? 25.353 23.733 28.074 1.000 32.004  0 77   CYS A C   1 ? 
ATOM   574  O O   . CYS A 1 77  ? 24.990 22.585 27.900 1.000 34.900  0 77   CYS A O   1 ? 
ATOM   575  C CB  . CYS A 1 77  ? 23.298 24.944 27.990 1.000 26.016  0 77   CYS A CB  1 ? 
ATOM   576  S SG  . CYS A 1 77  ? 22.419 26.377 27.346 1.000 27.366  0 77   CYS A SG  1 ? 
ATOM   577  N N   . LYS A 1 78  ? 26.270 24.114 28.968 1.000 29.970  0 78   LYS A N   1 ? 
ATOM   578  C CA  . LYS A 1 78  ? 26.874 23.195 29.927 1.000 37.955  0 78   LYS A CA  1 ? 
ATOM   579  C C   . LYS A 1 78  ? 26.321 23.451 31.318 1.000 36.995  0 78   LYS A C   1 ? 
ATOM   580  O O   . LYS A 1 78  ? 26.363 22.593 32.205 1.000 46.854  0 78   LYS A O   1 ? 
ATOM   581  C CB  . LYS A 1 78  ? 28.380 23.422 30.073 1.000 47.151  0 78   LYS A CB  1 ? 
ATOM   582  C CG  . LYS A 1 78  ? 29.237 23.040 28.878 1.000 62.154  0 78   LYS A CG  1 ? 
ATOM   583  C CD  . LYS A 1 78  ? 30.721 23.012 29.238 1.000 75.829  0 78   LYS A CD  1 ? 
ATOM   584  C CE  . LYS A 1 78  ? 31.652 22.954 28.041 1.000 89.033  0 78   LYS A CE  1 ? 
ATOM   585  N NZ  . LYS A 1 78  ? 31.756 24.265 27.349 1.000 87.026  0 78   LYS A NZ  1 ? 
ATOM   586  N N   . ARG A 1 79  ? 25.856 24.682 31.535 1.000 32.106  0 79   ARG A N   1 ? 
ATOM   587  C CA  . ARG A 1 79  ? 25.390 25.087 32.841 1.000 32.997  0 79   ARG A CA  1 ? 
ATOM   588  C C   . ARG A 1 79  ? 23.897 25.364 32.705 1.000 30.667  0 79   ARG A C   1 ? 
ATOM   589  O O   . ARG A 1 79  ? 23.397 25.499 31.595 1.000 29.161  0 79   ARG A O   1 ? 
ATOM   590  C CB  . ARG A 1 79  ? 26.027 26.393 33.345 1.000 38.464  0 79   ARG A CB  1 ? 
ATOM   591  C CG  . ARG A 1 79  ? 27.536 26.473 33.142 1.000 65.342  0 79   ARG A CG  1 ? 
ATOM   592  C CD  . ARG A 1 79  ? 28.381 26.749 34.383 1.000 85.785  0 79   ARG A CD  1 ? 
ATOM   593  N NE  . ARG A 1 79  ? 28.963 25.520 34.940 1.000 99.605  0 79   ARG A NE  1 ? 
ATOM   594  C CZ  . ARG A 1 79  ? 28.855 25.113 36.207 1.000 111.013 0 79   ARG A CZ  1 ? 
ATOM   595  N NH1 . ARG A 1 79  ? 28.210 25.848 37.100 1.000 118.282 0 79   ARG A NH1 1 ? 
ATOM   596  N NH2 . ARG A 1 79  ? 29.402 23.967 36.582 1.000 104.487 0 79   ARG A NH2 1 ? 
ATOM   597  N N   . PHE A 1 80  ? 23.266 25.604 33.844 1.000 26.312  0 80   PHE A N   1 ? 
ATOM   598  C CA  . PHE A 1 80  ? 21.874 26.004 33.835 1.000 27.133  0 80   PHE A CA  1 ? 
ATOM   599  C C   . PHE A 1 80  ? 21.722 27.451 33.401 1.000 28.706  0 80   PHE A C   1 ? 
ATOM   600  O O   . PHE A 1 80  ? 22.668 28.221 33.369 1.000 30.068  0 80   PHE A O   1 ? 
ATOM   601  C CB  . PHE A 1 80  ? 21.259 25.815 35.204 1.000 24.992  0 80   PHE A CB  1 ? 
ATOM   602  C CG  . PHE A 1 80  ? 21.165 24.371 35.605 1.000 24.763  0 80   PHE A CG  1 ? 
ATOM   603  C CD1 . PHE A 1 80  ? 20.776 23.397 34.689 1.000 28.236  0 80   PHE A CD1 1 ? 
ATOM   604  C CD2 . PHE A 1 80  ? 21.430 24.020 36.910 1.000 30.833  0 80   PHE A CD2 1 ? 
ATOM   605  C CE1 . PHE A 1 80  ? 20.658 22.080 35.092 1.000 30.093  0 80   PHE A CE1 1 ? 
ATOM   606  C CE2 . PHE A 1 80  ? 21.333 22.692 37.303 1.000 31.506  0 80   PHE A CE2 1 ? 
ATOM   607  C CZ  . PHE A 1 80  ? 20.955 21.735 36.386 1.000 33.571  0 80   PHE A CZ  1 ? 
ATOM   608  N N   . GLY A 1 81  ? 20.480 27.787 33.034 1.000 25.791  0 81   GLY A N   1 ? 
ATOM   609  C CA  . GLY A 1 81  ? 20.225 29.053 32.409 1.000 24.469  0 81   GLY A CA  1 ? 
ATOM   610  C C   . GLY A 1 81  ? 19.772 30.093 33.422 1.000 23.080  0 81   GLY A C   1 ? 
ATOM   611  O O   . GLY A 1 81  ? 19.257 29.788 34.483 1.000 26.006  0 81   GLY A O   1 ? 
ATOM   612  N N   . ARG A 1 82  ? 19.909 31.335 32.989 1.000 22.172  0 82   ARG A N   1 ? 
ATOM   613  C CA  . ARG A 1 82  ? 19.495 32.472 33.758 1.000 24.720  0 82   ARG A CA  1 ? 
ATOM   614  C C   . ARG A 1 82  ? 17.982 32.551 33.769 1.000 21.833  0 82   ARG A C   1 ? 
ATOM   615  O O   . ARG A 1 82  ? 17.325 32.481 32.735 1.000 22.295  0 82   ARG A O   1 ? 
ATOM   616  C CB  . ARG A 1 82  ? 20.125 33.702 33.116 1.000 27.040  0 82   ARG A CB  1 ? 
ATOM   617  C CG  . ARG A 1 82  ? 19.903 34.990 33.880 1.000 36.567  0 82   ARG A CG  1 ? 
ATOM   618  C CD  . ARG A 1 82  ? 20.833 36.019 33.234 1.000 38.958  0 82   ARG A CD  1 ? 
ATOM   619  N NE  . ARG A 1 82  ? 20.943 37.293 33.923 1.000 50.717  0 82   ARG A NE  1 ? 
ATOM   620  C CZ  . ARG A 1 82  ? 19.976 38.205 33.978 1.000 47.575  0 82   ARG A CZ  1 ? 
ATOM   621  N NH1 . ARG A 1 82  ? 18.890 38.090 33.239 1.000 54.711  0 82   ARG A NH1 1 ? 
ATOM   622  N NH2 . ARG A 1 82  ? 20.069 39.221 34.808 1.000 57.155  0 82   ARG A NH2 1 ? 
ATOM   623  N N   . PRO A 1 83  ? 17.352 32.733 34.937 1.000 20.895  0 83   PRO A N   1 ? 
ATOM   624  C CA  . PRO A 1 83  ? 15.910 32.908 34.999 1.000 19.168  0 83   PRO A CA  1 ? 
ATOM   625  C C   . PRO A 1 83  ? 15.538 34.136 34.214 1.000 19.957  0 83   PRO A C   1 ? 
ATOM   626  O O   . PRO A 1 83  ? 16.288 35.090 34.120 1.000 24.177  0 83   PRO A O   1 ? 
ATOM   627  C CB  . PRO A 1 83  ? 15.608 33.167 36.479 1.000 24.648  0 83   PRO A CB  1 ? 
ATOM   628  C CG  . PRO A 1 83  ? 16.790 32.567 37.181 1.000 27.106  0 83   PRO A CG  1 ? 
ATOM   629  C CD  . PRO A 1 83  ? 17.971 32.718 36.263 1.000 26.641  0 83   PRO A CD  1 ? 
ATOM   630  N N   . PRO A 1 84  ? 14.318 34.235 33.718 1.000 22.097  0 84   PRO A N   1 ? 
ATOM   631  C CA  . PRO A 1 84  ? 13.289 33.271 34.035 1.000 20.498  0 84   PRO A CA  1 ? 
ATOM   632  C C   . PRO A 1 84  ? 13.283 32.123 33.055 1.000 21.972  0 84   PRO A C   1 ? 
ATOM   633  O O   . PRO A 1 84  ? 13.408 32.333 31.861 1.000 23.836  0 84   PRO A O   1 ? 
ATOM   634  C CB  . PRO A 1 84  ? 12.024 34.127 33.939 1.000 22.948  0 84   PRO A CB  1 ? 
ATOM   635  C CG  . PRO A 1 84  ? 12.339 35.132 32.867 1.000 24.971  0 84   PRO A CG  1 ? 
ATOM   636  C CD  . PRO A 1 84  ? 13.798 35.416 33.008 1.000 24.785  0 84   PRO A CD  1 ? 
ATOM   637  N N   . THR A 1 85  ? 13.073 30.924 33.582 1.000 21.492  0 85   THR A N   1 ? 
ATOM   638  C CA  . THR A 1 85  ? 13.060 29.729 32.774 1.000 19.350  0 85   THR A CA  1 ? 
ATOM   639  C C   . THR A 1 85  ? 12.082 28.734 33.358 1.000 19.571  0 85   THR A C   1 ? 
ATOM   640  O O   . THR A 1 85  ? 12.293 28.224 34.446 1.000 20.326  0 85   THR A O   1 ? 
ATOM   641  C CB  . THR A 1 85  ? 14.414 29.001 32.804 1.000 22.242  0 85   THR A CB  1 ? 
ATOM   642  O OG1 . THR A 1 85  ? 14.815 28.804 34.160 1.000 25.024  0 85   THR A OG1 1 ? 
ATOM   643  C CG2 . THR A 1 85  ? 15.461 29.725 31.994 1.000 23.518  0 85   THR A CG2 1 ? 
ATOM   644  N N   . THR A 1 86  ? 11.059 28.378 32.594 1.000 19.508  0 86   THR A N   1 ? 
ATOM   645  C CA  . THR A 1 86  ? 10.224 27.256 32.942 1.000 19.510  0 86   THR A CA  1 ? 
ATOM   646  C C   . THR A 1 86  ? 11.114 26.019 32.828 1.000 20.998  0 86   THR A C   1 ? 
ATOM   647  O O   . THR A 1 86  ? 11.816 25.926 31.854 1.000 21.770  0 86   THR A O   1 ? 
ATOM   648  C CB  . THR A 1 86  ? 9.076  27.089 31.951 1.000 21.374  0 86   THR A CB  1 ? 
ATOM   649  O OG1 . THR A 1 86  ? 8.561  28.379 31.671 1.000 20.553  0 86   THR A OG1 1 ? 
ATOM   650  C CG2 . THR A 1 86  ? 7.992  26.189 32.462 1.000 21.505  0 86   THR A CG2 1 ? 
ATOM   651  N N   . LEU A 1 87  ? 11.095 25.139 33.804 1.000 19.648  0 87   LEU A N   1 ? 
ATOM   652  C CA  . LEU A 1 87  ? 12.023 24.024 33.777 1.000 19.864  0 87   LEU A CA  1 ? 
ATOM   653  C C   . LEU A 1 87  ? 11.336 22.687 33.744 1.000 20.571  0 87   LEU A C   1 ? 
ATOM   654  O O   . LEU A 1 87  ? 10.477 22.425 34.573 1.000 22.021  0 87   LEU A O   1 ? 
ATOM   655  C CB  . LEU A 1 87  ? 12.857 24.108 35.047 1.000 21.245  0 87   LEU A CB  1 ? 
ATOM   656  C CG  . LEU A 1 87  ? 13.820 25.276 35.130 1.000 23.186  0 87   LEU A CG  1 ? 
ATOM   657  C CD1 . LEU A 1 87  ? 14.449 25.327 36.501 1.000 25.926  0 87   LEU A CD1 1 ? 
ATOM   658  C CD2 . LEU A 1 87  ? 14.857 25.167 34.072 1.000 24.515  0 87   LEU A CD2 1 ? 
ATOM   659  N N   . ALA A 1 88  ? 11.804 21.821 32.834 1.000 20.173  0 88   ALA A N   1 ? 
ATOM   660  C CA  . ALA A 1 88  ? 11.495 20.412 32.896 1.000 19.663  0 88   ALA A CA  1 ? 
ATOM   661  C C   . ALA A 1 88  ? 12.671 19.788 33.627 1.000 20.041  0 88   ALA A C   1 ? 
ATOM   662  O O   . ALA A 1 88  ? 13.802 19.984 33.216 1.000 23.234  0 88   ALA A O   1 ? 
ATOM   663  C CB  . ALA A 1 88  ? 11.373 19.854 31.531 1.000 23.387  0 88   ALA A CB  1 ? 
ATOM   664  N N   . GLU A 1 89  ? 12.366 19.096 34.738 1.000 20.427  0 89   GLU A N   1 ? 
ATOM   665  C CA  . GLU A 1 89  ? 13.415 18.561 35.578 1.000 19.590  0 89   GLU A CA  1 ? 
ATOM   666  C C   . GLU A 1 89  ? 13.255 17.049 35.664 1.000 22.066  0 89   GLU A C   1 ? 
ATOM   667  O O   . GLU A 1 89  ? 12.137 16.537 35.767 1.000 22.178  0 89   GLU A O   1 ? 
ATOM   668  C CB  . GLU A 1 89  ? 13.336 19.130 36.990 1.000 22.765  0 89   GLU A CB  1 ? 
ATOM   669  C CG  . GLU A 1 89  ? 13.288 20.652 37.008 1.000 26.005  0 89   GLU A CG  1 ? 
ATOM   670  C CD  . GLU A 1 89  ? 13.280 21.217 38.417 1.000 26.243  0 89   GLU A CD  1 ? 
ATOM   671  O OE1 . GLU A 1 89  ? 12.417 20.833 39.228 1.000 26.454  0 89   GLU A OE1 1 ? 
ATOM   672  O OE2 . GLU A 1 89  ? 14.121 22.068 38.660 1.000 28.766  0 89   GLU A OE2 1 ? 
ATOM   673  N N   . PHE A 1 90  ? 14.385 16.376 35.717 1.000 23.187  0 90   PHE A N   1 ? 
ATOM   674  C CA  . PHE A 1 90  ? 14.261 14.940 35.752 1.000 22.692  0 90   PHE A CA  1 ? 
ATOM   675  C C   . PHE A 1 90  ? 15.483 14.335 36.407 1.000 22.779  0 90   PHE A C   1 ? 
ATOM   676  O O   . PHE A 1 90  ? 16.593 14.835 36.285 1.000 24.691  0 90   PHE A O   1 ? 
ATOM   677  C CB  . PHE A 1 90  ? 14.035 14.376 34.347 1.000 22.802  0 90   PHE A CB  1 ? 
ATOM   678  C CG  . PHE A 1 90  ? 14.988 14.895 33.342 1.000 21.654  0 90   PHE A CG  1 ? 
ATOM   679  C CD1 . PHE A 1 90  ? 14.704 16.077 32.681 1.000 25.420  0 90   PHE A CD1 1 ? 
ATOM   680  C CD2 . PHE A 1 90  ? 16.200 14.290 33.095 1.000 27.127  0 90   PHE A CD2 1 ? 
ATOM   681  C CE1 . PHE A 1 90  ? 15.605 16.612 31.777 1.000 27.150  0 90   PHE A CE1 1 ? 
ATOM   682  C CE2 . PHE A 1 90  ? 17.083 14.825 32.186 1.000 27.155  0 90   PHE A CE2 1 ? 
ATOM   683  C CZ  . PHE A 1 90  ? 16.792 15.992 31.524 1.000 27.018  0 90   PHE A CZ  1 ? 
ATOM   684  N N   . SER A 1 91  ? 15.203 13.230 37.068 1.000 25.756  0 91   SER A N   1 ? 
ATOM   685  C CA  . SER A 1 91  ? 16.250 12.365 37.576 1.000 25.222  0 91   SER A CA  1 ? 
ATOM   686  C C   . SER A 1 91  ? 15.906 10.965 37.101 1.000 23.569  0 91   SER A C   1 ? 
ATOM   687  O O   . SER A 1 91  ? 14.804 10.511 37.345 1.000 27.573  0 91   SER A O   1 ? 
ATOM   688  C CB  . SER A 1 91  ? 16.301 12.530 39.070 1.000 28.146  0 91   SER A CB  1 ? 
ATOM   689  O OG  . SER A 1 91  ? 16.908 13.765 39.391 1.000 29.767  0 91   SER A OG  1 ? 
ATOM   690  N N   . LEU A 1 92  ? 16.857 10.303 36.423 1.000 23.868  0 92   LEU A N   1 ? 
ATOM   691  C CA  . LEU A 1 92  ? 16.509 9.051  35.771 1.000 26.024  0 92   LEU A CA  1 ? 
ATOM   692  C C   . LEU A 1 92  ? 17.168 7.881  36.521 1.000 25.366  0 92   LEU A C   1 ? 
ATOM   693  O O   . LEU A 1 92  ? 18.288 8.013  37.011 1.000 29.005  0 92   LEU A O   1 ? 
ATOM   694  C CB  . LEU A 1 92  ? 17.005 9.072  34.341 1.000 25.938  0 92   LEU A CB  1 ? 
ATOM   695  C CG  . LEU A 1 92  ? 16.599 10.289 33.504 1.000 29.951  0 92   LEU A CG  1 ? 
ATOM   696  C CD1 . LEU A 1 92  ? 17.203 10.169 32.129 1.000 30.969  0 92   LEU A CD1 1 ? 
ATOM   697  C CD2 . LEU A 1 92  ? 15.116 10.395 33.469 1.000 27.141  0 92   LEU A CD2 1 ? 
ATOM   698  N N   . ASN A 1 93  ? 16.429 6.789  36.555 1.000 28.248  0 93   ASN A N   1 ? 
ATOM   699  C CA  . ASN A 1 93  ? 16.958 5.502  37.025 1.000 29.635  0 93   ASN A CA  1 ? 
ATOM   700  C C   . ASN A 1 93  ? 17.443 5.644  38.458 1.000 30.655  0 93   ASN A C   1 ? 
ATOM   701  O O   . ASN A 1 93  ? 18.579 5.330  38.763 1.000 32.088  0 93   ASN A O   1 ? 
ATOM   702  C CB  . ASN A 1 93  ? 18.130 5.054  36.159 1.000 29.866  0 93   ASN A CB  1 ? 
ATOM   703  C CG  . ASN A 1 93  ? 17.733 4.963  34.705 1.000 33.706  0 93   ASN A CG  1 ? 
ATOM   704  O OD1 . ASN A 1 93  ? 18.131 5.829  33.928 1.000 33.457  0 93   ASN A OD1 1 ? 
ATOM   705  N ND2 . ASN A 1 93  ? 16.913 3.980  34.350 1.000 34.689  0 93   ASN A ND2 1 ? 
ATOM   706  N N   . GLN A 1 94  ? 16.568 6.162  39.303 1.000 29.414  0 94   GLN A N   1 ? 
ATOM   707  C CA  . GLN A 1 94  ? 16.895 6.391  40.704 1.000 32.547  0 94   GLN A CA  1 ? 
ATOM   708  C C   . GLN A 1 94  ? 16.200 5.280  41.471 1.000 31.993  0 94   GLN A C   1 ? 
ATOM   709  O O   . GLN A 1 94  ? 15.005 5.319  41.683 1.000 29.000  0 94   GLN A O   1 ? 
ATOM   710  C CB  . GLN A 1 94  ? 16.438 7.763  41.188 1.000 34.164  0 94   GLN A CB  1 ? 
ATOM   711  C CG  . GLN A 1 94  ? 17.026 8.871  40.347 1.000 37.180  0 94   GLN A CG  1 ? 
ATOM   712  C CD  . GLN A 1 94  ? 18.498 8.989  40.582 1.000 45.033  0 94   GLN A CD  1 ? 
ATOM   713  O OE1 . GLN A 1 94  ? 18.944 9.096  41.725 1.000 50.963  0 94   GLN A OE1 1 ? 
ATOM   714  N NE2 . GLN A 1 94  ? 19.259 8.978  39.505 1.000 42.172  0 94   GLN A NE2 1 ? 
ATOM   715  N N   . TYR A 1 95  ? 16.957 4.226  41.802 1.000 32.498  0 95   TYR A N   1 ? 
ATOM   716  C CA  . TYR A 1 95  ? 16.329 3.097  42.472 1.000 34.515  0 95   TYR A CA  1 ? 
ATOM   717  C C   . TYR A 1 95  ? 15.137 2.568  41.682 1.000 34.723  0 95   TYR A C   1 ? 
ATOM   718  O O   . TYR A 1 95  ? 14.096 2.273  42.239 1.000 35.654  0 95   TYR A O   1 ? 
ATOM   719  C CB  . TYR A 1 95  ? 16.013 3.459  43.923 1.000 36.410  0 95   TYR A CB  1 ? 
ATOM   720  C CG  . TYR A 1 95  ? 17.251 3.845  44.680 1.000 43.374  0 95   TYR A CG  1 ? 
ATOM   721  C CD1 . TYR A 1 95  ? 18.144 2.885  45.145 1.000 49.929  0 95   TYR A CD1 1 ? 
ATOM   722  C CD2 . TYR A 1 95  ? 17.578 5.177  44.868 1.000 50.229  0 95   TYR A CD2 1 ? 
ATOM   723  C CE1 . TYR A 1 95  ? 19.298 3.242  45.827 1.000 54.107  0 95   TYR A CE1 1 ? 
ATOM   724  C CE2 . TYR A 1 95  ? 18.730 5.554  45.542 1.000 54.745  0 95   TYR A CE2 1 ? 
ATOM   725  C CZ  . TYR A 1 95  ? 19.585 4.583  46.034 1.000 60.086  0 95   TYR A CZ  1 ? 
ATOM   726  O OH  . TYR A 1 95  ? 20.718 4.973  46.702 1.000 65.340  0 95   TYR A OH  1 ? 
ATOM   727  N N   . GLY A 1 96  ? 15.307 2.436  40.354 1.000 32.375  0 96   GLY A N   1 ? 
ATOM   728  C CA  . GLY A 1 96  ? 14.338 1.789  39.488 1.000 35.905  0 96   GLY A CA  1 ? 
ATOM   729  C C   . GLY A 1 96  ? 13.235 2.730  39.015 1.000 37.326  0 96   GLY A C   1 ? 
ATOM   730  O O   . GLY A 1 96  ? 12.354 2.327  38.289 1.000 33.763  0 96   GLY A O   1 ? 
ATOM   731  N N   . LYS A 1 97  ? 13.310 4.016  39.394 1.000 35.145  0 97   LYS A N   1 ? 
ATOM   732  C CA  . LYS A 1 97  ? 12.260 4.950  39.039 1.000 33.872  0 97   LYS A CA  1 ? 
ATOM   733  C C   . LYS A 1 97  ? 12.883 6.169  38.356 1.000 28.292  0 97   LYS A C   1 ? 
ATOM   734  O O   . LYS A 1 97  ? 14.044 6.537  38.603 1.000 30.214  0 97   LYS A O   1 ? 
ATOM   735  C CB  . LYS A 1 97  ? 11.526 5.428  40.290 1.000 40.648  0 97   LYS A CB  1 ? 
ATOM   736  C CG  . LYS A 1 97  ? 10.743 4.372  41.067 1.000 48.087  0 97   LYS A CG  1 ? 
ATOM   737  C CD  . LYS A 1 97  ? 9.833  3.612  40.175 1.000 51.981  0 97   LYS A CD  1 ? 
ATOM   738  C CE  . LYS A 1 97  ? 8.683  2.965  40.912 1.000 62.526  0 97   LYS A CE  1 ? 
ATOM   739  N NZ  . LYS A 1 97  ? 7.860  2.231  39.928 1.000 70.374  0 97   LYS A NZ  1 ? 
ATOM   740  N N   . ASP A 1 98  ? 12.071 6.783  37.508 1.000 29.852  0 98   ASP A N   1 ? 
ATOM   741  C CA  . ASP A 1 98  ? 12.376 8.093  36.957 1.000 27.430  0 98   ASP A CA  1 ? 
ATOM   742  C C   . ASP A 1 98  ? 11.468 9.103  37.655 1.000 24.953  0 98   ASP A C   1 ? 
ATOM   743  O O   . ASP A 1 98  ? 10.323 8.821  38.007 1.000 26.514  0 98   ASP A O   1 ? 
ATOM   744  C CB  . ASP A 1 98  ? 12.072 8.172  35.453 1.000 27.380  0 98   ASP A CB  1 ? 
ATOM   745  C CG  . ASP A 1 98  ? 13.007 7.455  34.516 1.000 33.139  0 98   ASP A CG  1 ? 
ATOM   746  O OD1 . ASP A 1 98  ? 14.032 6.854  34.966 1.000 28.673  0 98   ASP A OD1 1 ? 
ATOM   747  O OD2 . ASP A 1 98  ? 12.723 7.540  33.311 1.000 29.726  0 98   ASP A OD2 1 ? 
ATOM   748  N N   . TYR A 1 99  ? 12.007 10.297 37.876 1.000 25.471  0 99   TYR A N   1 ? 
ATOM   749  C CA  . TYR A 1 99  ? 11.218 11.340 38.512 1.000 26.257  0 99   TYR A CA  1 ? 
ATOM   750  C C   . TYR A 1 99  ? 11.221 12.563 37.617 1.000 24.027  0 99   TYR A C   1 ? 
ATOM   751  O O   . TYR A 1 99  ? 12.324 12.982 37.239 1.000 26.432  0 99   TYR A O   1 ? 
ATOM   752  C CB  . TYR A 1 99  ? 11.863 11.700 39.841 1.000 29.097  0 99   TYR A CB  1 ? 
ATOM   753  C CG  . TYR A 1 99  ? 11.757 10.561 40.836 1.000 28.904  0 99   TYR A CG  1 ? 
ATOM   754  C CD1 . TYR A 1 99  ? 10.554 10.288 41.456 1.000 34.529  0 99   TYR A CD1 1 ? 
ATOM   755  C CD2 . TYR A 1 99  ? 12.821 9.705  41.062 1.000 37.096  0 99   TYR A CD2 1 ? 
ATOM   756  C CE1 . TYR A 1 99  ? 10.420 9.231  42.348 1.000 42.264  0 99   TYR A CE1 1 ? 
ATOM   757  C CE2 . TYR A 1 99  ? 12.696 8.627  41.927 1.000 36.892  0 99   TYR A CE2 1 ? 
ATOM   758  C CZ  . TYR A 1 99  ? 11.508 8.417  42.597 1.000 42.487  0 99   TYR A CZ  1 ? 
ATOM   759  O OH  . TYR A 1 99  ? 11.402 7.374  43.481 1.000 41.410  0 99   TYR A OH  1 ? 
ATOM   760  N N   . ILE A 1 100 ? 10.033 13.059 37.297 1.000 24.412  0 100  ILE A N   1 ? 
ATOM   761  C CA  . ILE A 1 100 ? 9.950  14.232 36.437 1.000 24.226  0 100  ILE A CA  1 ? 
ATOM   762  C C   . ILE A 1 100 ? 9.069  15.270 37.116 1.000 24.190  0 100  ILE A C   1 ? 
ATOM   763  O O   . ILE A 1 100 ? 8.144  14.956 37.865 1.000 26.271  0 100  ILE A O   1 ? 
ATOM   764  C CB  . ILE A 1 100 ? 9.423  13.900 35.029 1.000 26.444  0 100  ILE A CB  1 ? 
ATOM   765  C CG1 . ILE A 1 100 ? 7.967  13.449 35.056 1.000 27.012  0 100  ILE A CG1 1 ? 
ATOM   766  C CG2 . ILE A 1 100 ? 10.344 12.887 34.399 1.000 25.430  0 100  ILE A CG2 1 ? 
ATOM   767  C CD1 . ILE A 1 100 ? 7.392  13.271 33.708 1.000 30.797  0 100  ILE A CD1 1 ? 
ATOM   768  N N   . ASP A 1 101 ? 9.350  16.534 36.778 1.000 23.038  0 101  ASP A N   1 ? 
ATOM   769  C CA  . ASP A 1 101 ? 8.499  17.596 37.235 1.000 23.598  0 101  ASP A CA  1 ? 
ATOM   770  C C   . ASP A 1 101 ? 8.741  18.778 36.319 1.000 19.888  0 101  ASP A C   1 ? 
ATOM   771  O O   . ASP A 1 101 ? 9.694  18.781 35.549 1.000 21.715  0 101  ASP A O   1 ? 
ATOM   772  C CB  . ASP A 1 101 ? 8.772  17.974 38.681 1.000 24.213  0 101  ASP A CB  1 ? 
ATOM   773  C CG  . ASP A 1 101 ? 10.136 18.562 38.901 1.000 26.598  0 101  ASP A CG  1 ? 
ATOM   774  O OD1 . ASP A 1 101 ? 10.346 19.744 38.593 1.000 26.562  0 101  ASP A OD1 1 ? 
ATOM   775  O OD2 . ASP A 1 101 ? 11.052 17.823 39.326 1.000 29.567  0 101  ASP A OD2 1 ? 
ATOM   776  N N   . ILE A 1 102 ? 7.789  19.695 36.396 1.000 21.061  0 102  ILE A N   1 ? 
ATOM   777  C CA  . ILE A 1 102 ? 7.970  21.034 35.880 1.000 18.956  0 102  ILE A CA  1 ? 
ATOM   778  C C   . ILE A 1 102 ? 8.066  21.955 37.070 1.000 21.255  0 102  ILE A C   1 ? 
ATOM   779  O O   . ILE A 1 102 ? 7.390  21.752 38.077 1.000 22.281  0 102  ILE A O   1 ? 
ATOM   780  C CB  . ILE A 1 102 ? 6.836  21.437 34.943 1.000 21.357  0 102  ILE A CB  1 ? 
ATOM   781  C CG1 . ILE A 1 102 ? 6.935  20.631 33.650 1.000 24.859  0 102  ILE A CG1 1 ? 
ATOM   782  C CG2 . ILE A 1 102 ? 6.943  22.918 34.609 1.000 24.940  0 102  ILE A CG2 1 ? 
ATOM   783  C CD1 . ILE A 1 102 ? 5.768  20.901 32.775 1.000 32.181  0 102  ILE A CD1 1 ? 
ATOM   784  N N   . SER A 1 103 ? 8.936  22.935 36.923 1.000 22.726  0 103  SER A N   1 ? 
ATOM   785  C CA  . SER A 1 103 ? 9.172  23.848 38.030 1.000 19.776  0 103  SER A CA  1 ? 
ATOM   786  C C   . SER A 1 103 ? 9.095  25.267 37.500 1.000 21.297  0 103  SER A C   1 ? 
ATOM   787  O O   . SER A 1 103 ? 9.652  25.551 36.461 1.000 21.169  0 103  SER A O   1 ? 
ATOM   788  C CB  . SER A 1 103 ? 10.516 23.581 38.621 1.000 21.635  0 103  SER A CB  1 ? 
ATOM   789  O OG  . SER A 1 103 ? 10.881 24.544 39.579 1.000 24.109  0 103  SER A OG  1 ? 
ATOM   790  N N   . ASN A 1 104 ? 8.441  26.117 38.311 1.000 19.086  0 104  ASN A N   1 ? 
ATOM   791  C CA  . ASN A 1 104 ? 8.466  27.554 38.162 1.000 20.733  0 104  ASN A CA  1 ? 
ATOM   792  C C   . ASN A 1 104 ? 9.329  28.207 39.244 1.000 22.857  0 104  ASN A C   1 ? 
ATOM   793  O O   . ASN A 1 104 ? 9.244  29.410 39.448 1.000 20.636  0 104  ASN A O   1 ? 
ATOM   794  C CB  . ASN A 1 104 ? 7.029  28.079 38.269 1.000 21.398  0 104  ASN A CB  1 ? 
ATOM   795  C CG  . ASN A 1 104 ? 6.184  27.721 37.072 1.000 24.551  0 104  ASN A CG  1 ? 
ATOM   796  O OD1 . ASN A 1 104 ? 4.991  27.417 37.146 1.000 27.821  0 104  ASN A OD1 1 ? 
ATOM   797  N ND2 . ASN A 1 104 ? 6.797  27.837 35.944 1.000 21.543  0 104  ASN A ND2 1 ? 
ATOM   798  N N   . ILE A 1 105 ? 10.179 27.437 39.935 1.000 21.987  0 105  ILE A N   1 ? 
ATOM   799  C CA  . ILE A 1 105 ? 10.989 28.027 40.983 1.000 21.890  0 105  ILE A CA  1 ? 
ATOM   800  C C   . ILE A 1 105 ? 11.942 29.062 40.453 1.000 23.269  0 105  ILE A C   1 ? 
ATOM   801  O O   . ILE A 1 105 ? 12.422 29.917 41.214 1.000 21.608  0 105  ILE A O   1 ? 
ATOM   802  C CB  . ILE A 1 105 ? 11.701 26.913 41.765 1.000 21.936  0 105  ILE A CB  1 ? 
ATOM   803  C CG1 . ILE A 1 105 ? 10.634 26.138 42.550 1.000 26.646  0 105  ILE A CG1 1 ? 
ATOM   804  C CG2 . ILE A 1 105 ? 12.813 27.404 42.654 1.000 25.163  0 105  ILE A CG2 1 ? 
ATOM   805  C CD1 . ILE A 1 105 ? 11.118 24.810 43.080 1.000 30.370  0 105  ILE A CD1 1 ? 
ATOM   806  N N   . LYS A 1 106 ? 12.372 28.904 39.187 1.000 20.659  0 106  LYS A N   1 ? 
ATOM   807  C CA  . LYS A 1 106 ? 13.219 29.876 38.533 1.000 20.065  0 106  LYS A CA  1 ? 
ATOM   808  C C   . LYS A 1 106 ? 12.430 30.643 37.478 1.000 19.140  0 106  LYS A C   1 ? 
ATOM   809  O O   . LYS A 1 106 ? 13.023 31.144 36.538 1.000 21.982  0 106  LYS A O   1 ? 
ATOM   810  C CB  . LYS A 1 106 ? 14.367 29.143 37.838 1.000 23.981  0 106  LYS A CB  1 ? 
ATOM   811  C CG  . LYS A 1 106 ? 15.234 28.338 38.786 1.000 30.646  0 106  LYS A CG  1 ? 
ATOM   812  C CD  . LYS A 1 106 ? 16.062 29.262 39.568 1.000 39.978  0 106  LYS A CD  1 ? 
ATOM   813  C CE  . LYS A 1 106 ? 17.092 28.580 40.436 1.000 45.851  0 106  LYS A CE  1 ? 
ATOM   814  N NZ  . LYS A 1 106 ? 17.565 29.556 41.429 1.000 47.405  0 106  LYS A NZ  1 ? 
ATOM   815  N N   . GLY A 1 107 ? 11.156 30.843 37.743 1.000 20.094  0 107  GLY A N   1 ? 
ATOM   816  C CA  . GLY A 1 107 ? 10.336 31.692 36.925 1.000 20.389  0 107  GLY A CA  1 ? 
ATOM   817  C C   . GLY A 1 107 ? 9.770  30.901 35.764 1.000 23.562  0 107  GLY A C   1 ? 
ATOM   818  O O   . GLY A 1 107 ? 9.947  29.689 35.679 1.000 22.923  0 107  GLY A O   1 ? 
ATOM   819  N N   . PHE A 1 108 ? 9.229  31.656 34.846 1.000 20.986  0 108  PHE A N   1 ? 
ATOM   820  C CA  . PHE A 1 108 ? 8.516  31.101 33.716 1.000 21.698  0 108  PHE A CA  1 ? 
ATOM   821  C C   . PHE A 1 108 ? 8.828  31.948 32.510 1.000 20.840  0 108  PHE A C   1 ? 
ATOM   822  O O   . PHE A 1 108 ? 8.820  33.155 32.563 1.000 23.024  0 108  PHE A O   1 ? 
ATOM   823  C CB  . PHE A 1 108 ? 7.013  31.085 33.979 1.000 20.772  0 108  PHE A CB  1 ? 
ATOM   824  C CG  . PHE A 1 108 ? 6.156  30.654 32.821 1.000 19.019  0 108  PHE A CG  1 ? 
ATOM   825  C CD1 . PHE A 1 108 ? 5.895  31.512 31.770 1.000 20.714  0 108  PHE A CD1 1 ? 
ATOM   826  C CD2 . PHE A 1 108 ? 5.587  29.380 32.824 1.000 21.928  0 108  PHE A CD2 1 ? 
ATOM   827  C CE1 . PHE A 1 108 ? 5.087  31.096 30.733 1.000 22.336  0 108  PHE A CE1 1 ? 
ATOM   828  C CE2 . PHE A 1 108 ? 4.764  28.974 31.789 1.000 21.705  0 108  PHE A CE2 1 ? 
ATOM   829  C CZ  . PHE A 1 108 ? 4.515  29.831 30.762 1.000 21.281  0 108  PHE A CZ  1 ? 
ATOM   830  N N   . ASN A 1 109 ? 9.168  31.295 31.394 1.000 20.340  0 109  ASN A N   1 ? 
ATOM   831  C CA  . ASN A 1 109 ? 9.331  32.041 30.151 1.000 19.619  0 109  ASN A CA  1 ? 
ATOM   832  C C   . ASN A 1 109 ? 8.440  31.486 29.059 1.000 21.879  0 109  ASN A C   1 ? 
ATOM   833  O O   . ASN A 1 109 ? 7.829  32.234 28.318 1.000 23.154  0 109  ASN A O   1 ? 
ATOM   834  C CB  . ASN A 1 109 ? 10.782 32.087 29.684 1.000 21.456  0 109  ASN A CB  1 ? 
ATOM   835  C CG  . ASN A 1 109 ? 11.438 30.739 29.479 1.000 20.165  0 109  ASN A CG  1 ? 
ATOM   836  O OD1 . ASN A 1 109 ? 10.966 29.698 29.926 1.000 19.129  0 109  ASN A OD1 1 ? 
ATOM   837  N ND2 . ASN A 1 109 ? 12.521 30.773 28.748 1.000 20.775  0 109  ASN A ND2 1 ? 
ATOM   838  N N   . VAL A 1 110 ? 8.415  30.184 28.919 1.000 20.953  0 110  VAL A N   1 ? 
ATOM   839  C CA  . VAL A 1 110 ? 7.709  29.530 27.818 1.000 22.196  0 110  VAL A CA  1 ? 
ATOM   840  C C   . VAL A 1 110 ? 6.812  28.457 28.415 1.000 21.382  0 110  VAL A C   1 ? 
ATOM   841  O O   . VAL A 1 110 ? 7.214  27.672 29.298 1.000 22.506  0 110  VAL A O   1 ? 
ATOM   842  C CB  . VAL A 1 110 ? 8.723  28.946 26.811 1.000 26.715  0 110  VAL A CB  1 ? 
ATOM   843  C CG1 . VAL A 1 110 ? 8.064  28.111 25.738 1.000 32.528  0 110  VAL A CG1 1 ? 
ATOM   844  C CG2 . VAL A 1 110 ? 9.568  30.035 26.172 1.000 26.433  0 110  VAL A CG2 1 ? 
ATOM   845  N N   . PRO A 1 111 ? 5.569  28.288 27.935 1.000 19.922  0 111  PRO A N   1 ? 
ATOM   846  C CA  . PRO A 1 111 ? 4.708  27.222 28.417 1.000 20.081  0 111  PRO A CA  1 ? 
ATOM   847  C C   . PRO A 1 111 ? 5.250  25.877 27.969 1.000 21.283  0 111  PRO A C   1 ? 
ATOM   848  O O   . PRO A 1 111 ? 5.893  25.799 26.944 1.000 21.322  0 111  PRO A O   1 ? 
ATOM   849  C CB  . PRO A 1 111 ? 3.353  27.474 27.769 1.000 23.369  0 111  PRO A CB  1 ? 
ATOM   850  C CG  . PRO A 1 111 ? 3.641  28.389 26.661 1.000 26.061  0 111  PRO A CG  1 ? 
ATOM   851  C CD  . PRO A 1 111 ? 4.935  29.105 26.900 1.000 23.796  0 111  PRO A CD  1 ? 
ATOM   852  N N   . MET A 1 112 ? 4.978  24.862 28.747 1.000 21.572  0 112  MET A N   1 ? 
ATOM   853  C CA  . MET A 1 112 ? 5.653  23.597 28.547 1.000 22.233  0 112  MET A CA  1 ? 
ATOM   854  C C   . MET A 1 112 ? 4.770  22.439 28.993 1.000 22.829  0 112  MET A C   1 ? 
ATOM   855  O O   . MET A 1 112 ? 4.056  22.533 29.957 1.000 23.268  0 112  MET A O   1 ? 
ATOM   856  C CB  . MET A 1 112 ? 6.931  23.625 29.411 1.000 24.974  0 112  MET A CB  1 ? 
ATOM   857  C CG  . MET A 1 112 ? 7.598  22.331 29.522 1.000 35.629  0 112  MET A CG  1 ? 
ATOM   858  S SD  . MET A 1 112 ? 8.932  22.521 30.702 1.000 30.712  0 112  MET A SD  1 ? 
ATOM   859  C CE  . MET A 1 112 ? 9.997  23.585 29.753 1.000 30.207  0 112  MET A CE  1 ? 
ATOM   860  N N   . ASP A 1 113 ? 4.806  21.344 28.211 1.000 22.005  0 113  ASP A N   1 ? 
ATOM   861  C CA  . ASP A 1 113 ? 4.307  20.030 28.559 1.000 24.176  0 113  ASP A CA  1 ? 
ATOM   862  C C   . ASP A 1 113 ? 5.504  19.096 28.629 1.000 20.792  0 113  ASP A C   1 ? 
ATOM   863  O O   . ASP A 1 113 ? 6.402  19.153 27.789 1.000 22.833  0 113  ASP A O   1 ? 
ATOM   864  C CB  . ASP A 1 113 ? 3.296  19.550 27.520 1.000 24.025  0 113  ASP A CB  1 ? 
ATOM   865  C CG  . ASP A 1 113 ? 2.705  18.201 27.857 1.000 27.927  0 113  ASP A CG  1 ? 
ATOM   866  O OD1 . ASP A 1 113 ? 3.360  17.208 27.548 1.000 28.990  0 113  ASP A OD1 1 ? 
ATOM   867  O OD2 . ASP A 1 113 ? 1.682  18.184 28.564 1.000 28.046  0 113  ASP A OD2 1 ? 
ATOM   868  N N   . PHE A 1 114 ? 5.494  18.250 29.652 1.000 21.348  0 114  PHE A N   1 ? 
ATOM   869  C CA  . PHE A 1 114 ? 6.555  17.292 29.854 1.000 21.798  0 114  PHE A CA  1 ? 
ATOM   870  C C   . PHE A 1 114 ? 5.898  15.937 30.121 1.000 20.900  0 114  PHE A C   1 ? 
ATOM   871  O O   . PHE A 1 114 ? 5.280  15.747 31.159 1.000 24.119  0 114  PHE A O   1 ? 
ATOM   872  C CB  . PHE A 1 114 ? 7.413  17.722 31.030 1.000 21.526  0 114  PHE A CB  1 ? 
ATOM   873  C CG  . PHE A 1 114 ? 8.635  16.914 31.325 1.000 22.032  0 114  PHE A CG  1 ? 
ATOM   874  C CD1 . PHE A 1 114 ? 9.077  15.884 30.481 1.000 23.282  0 114  PHE A CD1 1 ? 
ATOM   875  C CD2 . PHE A 1 114 ? 9.360  17.142 32.489 1.000 24.112  0 114  PHE A CD2 1 ? 
ATOM   876  C CE1 . PHE A 1 114 ? 10.261 15.201 30.747 1.000 24.949  0 114  PHE A CE1 1 ? 
ATOM   877  C CE2 . PHE A 1 114 ? 10.504 16.425 32.776 1.000 24.278  0 114  PHE A CE2 1 ? 
ATOM   878  C CZ  . PHE A 1 114 ? 10.979 15.466 31.893 1.000 26.130  0 114  PHE A CZ  1 ? 
ATOM   879  N N   . SER A 1 115 ? 5.919  15.073 29.122 1.000 21.969  0 115  SER A N   1 ? 
ATOM   880  C CA  . SER A 1 115 ? 5.098  13.868 29.096 1.000 24.717  0 115  SER A CA  1 ? 
ATOM   881  C C   . SER A 1 115 ? 5.973  12.686 28.737 1.000 27.675  0 115  SER A C   1 ? 
ATOM   882  O O   . SER A 1 115 ? 6.885  12.757 27.910 1.000 27.679  0 115  SER A O   1 ? 
ATOM   883  C CB  . SER A 1 115 ? 3.963  13.970 28.114 1.000 27.137  0 115  SER A CB  1 ? 
ATOM   884  O OG  . SER A 1 115 ? 2.989  14.830 28.639 1.000 28.999  0 115  SER A OG  1 ? 
ATOM   885  N N   . PRO A 1 116 ? 5.720  11.535 29.366 1.000 26.628  0 116  PRO A N   1 ? 
ATOM   886  C CA  . PRO A 1 116 ? 6.349  10.293 28.904 1.000 26.667  0 116  PRO A CA  1 ? 
ATOM   887  C C   . PRO A 1 116 ? 5.794  9.922  27.541 1.000 26.730  0 116  PRO A C   1 ? 
ATOM   888  O O   . PRO A 1 116 ? 4.655  10.231 27.211 1.000 30.345  0 116  PRO A O   1 ? 
ATOM   889  C CB  . PRO A 1 116 ? 5.902  9.303  29.991 1.000 27.179  0 116  PRO A CB  1 ? 
ATOM   890  C CG  . PRO A 1 116 ? 4.586  9.821  30.448 1.000 29.417  0 116  PRO A CG  1 ? 
ATOM   891  C CD  . PRO A 1 116 ? 4.758  11.330 30.456 1.000 27.415  0 116  PRO A CD  1 ? 
ATOM   892  N N   . THR A 1 117 ? 6.643  9.313  26.735 1.000 29.052  0 117  THR A N   1 ? 
ATOM   893  C CA  . THR A 1 117 ? 6.197  8.741  25.469 1.000 31.164  0 117  THR A CA  1 ? 
ATOM   894  C C   . THR A 1 117 ? 6.094  7.240  25.599 1.000 35.555  0 117  THR A C   1 ? 
ATOM   895  O O   . THR A 1 117 ? 5.639  6.603  24.671 1.000 39.985  0 117  THR A O   1 ? 
ATOM   896  C CB  . THR A 1 117 ? 7.163  9.049  24.338 1.000 30.695  0 117  THR A CB  1 ? 
ATOM   897  O OG1 . THR A 1 117 ? 8.468  8.582  24.654 1.000 31.439  0 117  THR A OG1 1 ? 
ATOM   898  C CG2 . THR A 1 117 ? 7.244  10.529 24.043 1.000 33.838  0 117  THR A CG2 1 ? 
ATOM   899  N N   . THR A 1 118 ? 6.532  6.709  26.733 1.000 34.243  0 118  THR A N   1 ? 
ATOM   900  C CA  . THR A 1 118 ? 6.371  5.293  27.084 1.000 36.958  0 118  THR A CA  1 ? 
ATOM   901  C C   . THR A 1 118 ? 5.269  5.195  28.138 1.000 41.469  0 118  THR A C   1 ? 
ATOM   902  O O   . THR A 1 118 ? 4.737  6.201  28.587 1.000 45.095  0 118  THR A O   1 ? 
ATOM   903  C CB  . THR A 1 118 ? 7.744  4.722  27.476 1.000 35.534  0 118  THR A CB  1 ? 
ATOM   904  O OG1 . THR A 1 118 ? 8.264  5.524  28.545 1.000 37.273  0 118  THR A OG1 1 ? 
ATOM   905  C CG2 . THR A 1 118 ? 8.760  4.694  26.356 1.000 41.039  0 118  THR A CG2 1 ? 
ATOM   906  N N   . ARG A 1 119 ? 4.938  3.974  28.571 1.000 44.713  0 119  ARG A N   1 ? 
ATOM   907  C CA  . ARG A 1 119 ? 3.736  3.746  29.367 1.000 51.849  0 119  ARG A CA  1 ? 
ATOM   908  C C   . ARG A 1 119 ? 4.038  3.948  30.852 1.000 48.525  0 119  ARG A C   1 ? 
ATOM   909  O O   . ARG A 1 119 ? 5.199  3.892  31.273 1.000 49.245  0 119  ARG A O   1 ? 
ATOM   910  C CB  . ARG A 1 119 ? 3.221  2.300  29.233 1.000 68.119  0 119  ARG A CB  1 ? 
ATOM   911  C CG  . ARG A 1 119 ? 3.502  1.613  27.896 1.000 96.180  0 119  ARG A CG  1 ? 
ATOM   912  C CD  . ARG A 1 119 ? 3.427  0.085  27.944 1.000 108.018 0 119  ARG A CD  1 ? 
ATOM   913  N NE  . ARG A 1 119 ? 2.083  -0.445 28.180 1.000 112.969 0 119  ARG A NE  1 ? 
ATOM   914  C CZ  . ARG A 1 119 ? 1.080  -0.436 27.298 1.000 111.472 0 119  ARG A CZ  1 ? 
ATOM   915  N NH1 . ARG A 1 119 ? 1.260  -0.018 26.055 1.000 106.074 0 119  ARG A NH1 1 ? 
ATOM   916  N NH2 . ARG A 1 119 ? -0.113 -0.874 27.664 1.000 107.167 0 119  ARG A NH2 1 ? 
ATOM   917  N N   . GLY A 1 120 ? 2.976  4.160  31.648 1.000 42.542  0 120  GLY A N   1 ? 
ATOM   918  C CA  . GLY A 1 120 ? 3.038  3.911  33.078 1.000 43.365  0 120  GLY A CA  1 ? 
ATOM   919  C C   . GLY A 1 120 ? 3.171  5.150  33.963 1.000 44.741  0 120  GLY A C   1 ? 
ATOM   920  O O   . GLY A 1 120 ? 3.470  5.015  35.138 1.000 45.382  0 120  GLY A O   1 ? 
ATOM   921  N N   . CYS A 1 121 ? 2.989  6.352  33.411 1.000 39.590  0 121  CYS A N   1 ? 
ATOM   922  C CA  . CYS A 1 121 ? 2.850  7.524  34.252 1.000 37.330  0 121  CYS A CA  1 ? 
ATOM   923  C C   . CYS A 1 121 ? 2.234  8.615  33.384 1.000 39.612  0 121  CYS A C   1 ? 
ATOM   924  O O   . CYS A 1 121 ? 2.139  8.455  32.184 1.000 42.797  0 121  CYS A O   1 ? 
ATOM   925  C CB  . CYS A 1 121 ? 4.192  7.973  34.826 1.000 36.087  0 121  CYS A CB  1 ? 
ATOM   926  S SG  . CYS A 1 121 ? 5.469  8.084  33.543 1.000 34.730  0 121  CYS A SG  1 ? 
ATOM   927  N N   . ARG A 1 122 ? 1.894  9.721  34.008 1.000 35.529  0 122  ARG A N   1 ? 
ATOM   928  C CA  . ARG A 1 122 ? 1.183  10.819 33.385 1.000 37.598  0 122  ARG A CA  1 ? 
ATOM   929  C C   . ARG A 1 122 ? 2.208  11.924 33.187 1.000 32.826  0 122  ARG A C   1 ? 
ATOM   930  O O   . ARG A 1 122 ? 3.309  11.843 33.714 1.000 35.851  0 122  ARG A O   1 ? 
ATOM   931  C CB  . ARG A 1 122 ? 0.054  11.304 34.293 1.000 45.909  0 122  ARG A CB  1 ? 
ATOM   932  C CG  . ARG A 1 122 ? 0.540  12.002 35.559 1.000 53.169  0 122  ARG A CG  1 ? 
ATOM   933  C CD  . ARG A 1 122 ? -0.581 12.499 36.452 1.000 68.186  0 122  ARG A CD  1 ? 
ATOM   934  N NE  . ARG A 1 122 ? -0.036 13.369 37.490 1.000 81.075  0 122  ARG A NE  1 ? 
ATOM   935  C CZ  . ARG A 1 122 ? -0.055 14.707 37.462 1.000 93.690  0 122  ARG A CZ  1 ? 
ATOM   936  N NH1 . ARG A 1 122 ? -0.625 15.354 36.457 1.000 85.337  0 122  ARG A NH1 1 ? 
ATOM   937  N NH2 . ARG A 1 122 ? 0.509  15.399 38.443 1.000 93.145  0 122  ARG A NH2 1 ? 
ATOM   938  N N   . GLY A 1 123 ? 1.882  12.855 32.327 1.000 29.496  0 123  GLY A N   1 ? 
ATOM   939  C CA  . GLY A 1 123 ? 2.718  14.024 32.158 1.000 29.763  0 123  GLY A CA  1 ? 
ATOM   940  C C   . GLY A 1 123 ? 2.269  15.185 33.024 1.000 31.030  0 123  GLY A C   1 ? 
ATOM   941  O O   . GLY A 1 123 ? 1.254  15.152 33.708 1.000 31.821  0 123  GLY A O   1 ? 
ATOM   942  N N   . VAL A 1 124 ? 3.035  16.263 32.935 1.000 28.373  0 124  VAL A N   1 ? 
ATOM   943  C CA  . VAL A 1 124 ? 2.709  17.476 33.653 1.000 28.942  0 124  VAL A CA  1 ? 
ATOM   944  C C   . VAL A 1 124 ? 2.831  18.608 32.655 1.000 26.109  0 124  VAL A C   1 ? 
ATOM   945  O O   . VAL A 1 124 ? 3.499  18.505 31.630 1.000 24.024  0 124  VAL A O   1 ? 
ATOM   946  C CB  . VAL A 1 124 ? 3.622  17.699 34.866 1.000 32.950  0 124  VAL A CB  1 ? 
ATOM   947  C CG1 . VAL A 1 124 ? 3.186  16.878 36.068 1.000 41.681  0 124  VAL A CG1 1 ? 
ATOM   948  C CG2 . VAL A 1 124 ? 5.044  17.422 34.536 1.000 32.397  0 124  VAL A CG2 1 ? 
ATOM   949  N N   . ARG A 1 125 ? 2.114  19.670 32.942 1.000 25.863  0 125  ARG A N   1 ? 
ATOM   950  C CA  . ARG A 1 125 ? 2.022  20.749 32.005 1.000 25.071  0 125  ARG A CA  1 ? 
ATOM   951  C C   . ARG A 1 125 ? 1.938  22.030 32.819 1.000 27.797  0 125  ARG A C   1 ? 
ATOM   952  O O   . ARG A 1 125 ? 1.267  22.075 33.864 1.000 29.213  0 125  ARG A O   1 ? 
ATOM   953  C CB  . ARG A 1 125 ? 0.769  20.523 31.163 1.000 29.465  0 125  ARG A CB  1 ? 
ATOM   954  C CG  . ARG A 1 125 ? 0.456  21.644 30.192 1.000 40.160  0 125  ARG A CG  1 ? 
ATOM   955  C CD  . ARG A 1 125 ? -0.765 21.244 29.387 1.000 41.868  0 125  ARG A CD  1 ? 
ATOM   956  N NE  . ARG A 1 125 ? -0.426 20.147 28.488 1.000 46.961  0 125  ARG A NE  1 ? 
ATOM   957  C CZ  . ARG A 1 125 ? -1.111 19.841 27.385 1.000 53.130  0 125  ARG A CZ  1 ? 
ATOM   958  N NH1 . ARG A 1 125 ? -2.090 20.625 26.970 1.000 54.190  0 125  ARG A NH1 1 ? 
ATOM   959  N NH2 . ARG A 1 125 ? -0.775 18.788 26.664 1.000 53.180  0 125  ARG A NH2 1 ? 
ATOM   960  N N   . CYS A 1 126 ? 2.555  23.068 32.275 1.000 24.408  0 126  CYS A N   1 ? 
ATOM   961  C CA  . CYS A 1 126 ? 2.278  24.412 32.721 1.000 24.008  0 126  CYS A CA  1 ? 
ATOM   962  C C   . CYS A 1 126 ? 2.102  25.233 31.463 1.000 25.626  0 126  CYS A C   1 ? 
ATOM   963  O O   . CYS A 1 126 ? 3.100  25.580 30.814 1.000 25.866  0 126  CYS A O   1 ? 
ATOM   964  C CB  . CYS A 1 126 ? 3.401  24.950 33.579 1.000 25.533  0 126  CYS A CB  1 ? 
ATOM   965  S SG  . CYS A 1 126 ? 3.142  26.666 34.064 1.000 25.092  0 126  CYS A SG  1 ? 
ATOM   966  N N   . ALA A 1 127 ? 0.851  25.518 31.119 1.000 25.161  0 127  ALA A N   1 ? 
ATOM   967  C CA  . ALA A 1 127 ? 0.595  26.151 29.817 1.000 29.718  0 127  ALA A CA  1 ? 
ATOM   968  C C   . ALA A 1 127 ? -0.237 27.409 29.921 1.000 33.313  0 127  ALA A C   1 ? 
ATOM   969  O O   . ALA A 1 127 ? -0.660 27.939 28.916 1.000 35.408  0 127  ALA A O   1 ? 
ATOM   970  C CB  . ALA A 1 127 ? -0.101 25.206 28.908 1.000 30.036  0 127  ALA A CB  1 ? 
ATOM   971  N N   . ALA A 1 128 ? -0.349 27.956 31.108 1.000 28.546  0 128  ALA A N   1 ? 
ATOM   972  C CA  . ALA A 1 128 ? -1.100 29.171 31.319 1.000 28.187  0 128  ALA A CA  1 ? 
ATOM   973  C C   . ALA A 1 128 ? -0.261 30.342 30.862 1.000 29.177  0 128  ALA A C   1 ? 
ATOM   974  O O   . ALA A 1 128 ? 0.963  30.257 30.740 1.000 26.494  0 128  ALA A O   1 ? 
ATOM   975  C CB  . ALA A 1 128 ? -1.415 29.292 32.790 1.000 29.048  0 128  ALA A CB  1 ? 
ATOM   976  N N   . ASP A 1 129 ? -0.934 31.465 30.660 1.000 28.185  0 129  ASP A N   1 ? 
ATOM   977  C CA  . ASP A 1 129 ? -0.263 32.678 30.233 1.000 31.686  0 129  ASP A CA  1 ? 
ATOM   978  C C   . ASP A 1 129 ? 0.321  33.381 31.447 1.000 28.079  0 129  ASP A C   1 ? 
ATOM   979  O O   . ASP A 1 129 ? -0.157 34.428 31.863 1.000 27.147  0 129  ASP A O   1 ? 
ATOM   980  C CB  . ASP A 1 129 ? -1.217 33.635 29.521 1.000 35.640  0 129  ASP A CB  1 ? 
ATOM   981  C CG  . ASP A 1 129 ? -0.519 34.835 28.912 1.000 36.170  0 129  ASP A CG  1 ? 
ATOM   982  O OD1 . ASP A 1 129 ? 0.721  34.817 28.766 1.000 34.387  0 129  ASP A OD1 1 ? 
ATOM   983  O OD2 . ASP A 1 129 ? -1.239 35.782 28.571 1.000 44.625  0 129  ASP A OD2 1 ? 
ATOM   984  N N   . ILE A 1 130 ? 1.343  32.773 32.019 1.000 25.622  0 130  ILE A N   1 ? 
ATOM   985  C CA  . ILE A 1 130 ? 2.006  33.372 33.145 1.000 23.599  0 130  ILE A CA  1 ? 
ATOM   986  C C   . ILE A 1 130 ? 2.668  34.686 32.782 1.000 24.750  0 130  ILE A C   1 ? 
ATOM   987  O O   . ILE A 1 130 ? 2.687  35.586 33.603 1.000 27.187  0 130  ILE A O   1 ? 
ATOM   988  C CB  . ILE A 1 130 ? 2.936  32.339 33.774 1.000 24.237  0 130  ILE A CB  1 ? 
ATOM   989  C CG1 . ILE A 1 130 ? 2.086  31.283 34.472 1.000 27.761  0 130  ILE A CG1 1 ? 
ATOM   990  C CG2 . ILE A 1 130 ? 3.988  33.020 34.648 1.000 24.598  0 130  ILE A CG2 1 ? 
ATOM   991  C CD1 . ILE A 1 130 ? 2.842  30.175 35.110 1.000 29.936  0 130  ILE A CD1 1 ? 
ATOM   992  N N   . VAL A 1 131 ? 3.242  34.839 31.587 1.000 23.589  0 131  VAL A N   1 ? 
ATOM   993  C CA  . VAL A 1 131 ? 3.897  36.077 31.287 1.000 25.242  0 131  VAL A CA  1 ? 
ATOM   994  C C   . VAL A 1 131 ? 2.882  37.218 31.233 1.000 26.587  0 131  VAL A C   1 ? 
ATOM   995  O O   . VAL A 1 131 ? 3.151  38.297 31.770 1.000 27.798  0 131  VAL A O   1 ? 
ATOM   996  C CB  . VAL A 1 131 ? 4.707  35.971 29.982 1.000 26.536  0 131  VAL A CB  1 ? 
ATOM   997  C CG1 . VAL A 1 131 ? 5.354  37.290 29.621 1.000 31.031  0 131  VAL A CG1 1 ? 
ATOM   998  C CG2 . VAL A 1 131 ? 5.757  34.876 30.161 1.000 29.020  0 131  VAL A CG2 1 ? 
ATOM   999  N N   . GLY A 1 132 ? 1.755  36.955 30.576 1.000 26.138  0 132  GLY A N   1 ? 
ATOM   1000 C CA  . GLY A 1 132 ? 0.719  37.951 30.437 1.000 28.563  0 132  GLY A CA  1 ? 
ATOM   1001 C C   . GLY A 1 132 ? 0.178  38.407 31.793 1.000 32.179  0 132  GLY A C   1 ? 
ATOM   1002 O O   . GLY A 1 132 ? -0.124 39.590 31.980 1.000 31.642  0 132  GLY A O   1 ? 
ATOM   1003 N N   . GLN A 1 133 ? 0.047  37.471 32.733 1.000 25.758  0 133  GLN A N   1 ? 
ATOM   1004 C CA  . GLN A 1 133 ? -0.605 37.803 33.991 1.000 28.723  0 133  GLN A CA  1 ? 
ATOM   1005 C C   . GLN A 1 133 ? 0.426  38.154 35.074 1.000 27.082  0 133  GLN A C   1 ? 
ATOM   1006 O O   . GLN A 1 133 ? 0.060  38.427 36.200 1.000 25.411  0 133  GLN A O   1 ? 
ATOM   1007 C CB  . GLN A 1 133 ? -1.385 36.597 34.502 1.000 29.007  0 133  GLN A CB  1 ? 
ATOM   1008 C CG  . GLN A 1 133 ? -2.506 36.091 33.619 1.000 32.818  0 133  GLN A CG  1 ? 
ATOM   1009 C CD  . GLN A 1 133 ? -3.541 37.156 33.395 1.000 39.040  0 133  GLN A CD  1 ? 
ATOM   1010 O OE1 . GLN A 1 133 ? -3.516 38.237 33.973 1.000 38.325  0 133  GLN A OE1 1 ? 
ATOM   1011 N NE2 . GLN A 1 133 ? -4.451 36.879 32.492 1.000 53.008  0 133  GLN A NE2 1 ? 
ATOM   1012 N N   . CYS A 1 134 ? 1.702  38.130 34.721 1.000 25.244  0 134  CYS A N   1 ? 
ATOM   1013 C CA  . CYS A 1 134 ? 2.790  38.202 35.689 1.000 23.601  0 134  CYS A CA  1 ? 
ATOM   1014 C C   . CYS A 1 134 ? 2.680  39.480 36.516 1.000 25.754  0 134  CYS A C   1 ? 
ATOM   1015 O O   . CYS A 1 134 ? 2.540  40.577 35.982 1.000 26.535  0 134  CYS A O   1 ? 
ATOM   1016 C CB  . CYS A 1 134 ? 4.117  38.221 34.935 1.000 22.427  0 134  CYS A CB  1 ? 
ATOM   1017 S SG  . CYS A 1 134 ? 5.587  38.208 35.965 1.000 22.934  0 134  CYS A SG  1 ? 
ATOM   1018 N N   . PRO A 1 135 ? 2.797  39.380 37.842 1.000 27.348  0 135  PRO A N   1 ? 
ATOM   1019 C CA  . PRO A 1 135 ? 2.784  40.566 38.690 1.000 29.610  0 135  PRO A CA  1 ? 
ATOM   1020 C C   . PRO A 1 135 ? 3.843  41.524 38.225 1.000 27.288  0 135  PRO A C   1 ? 
ATOM   1021 O O   . PRO A 1 135 ? 4.955  41.150 37.896 1.000 27.854  0 135  PRO A O   1 ? 
ATOM   1022 C CB  . PRO A 1 135 ? 3.098  40.012 40.088 1.000 28.518  0 135  PRO A CB  1 ? 
ATOM   1023 C CG  . PRO A 1 135 ? 2.726  38.596 40.048 1.000 32.986  0 135  PRO A CG  1 ? 
ATOM   1024 C CD  . PRO A 1 135 ? 2.924  38.155 38.616 1.000 25.939  0 135  PRO A CD  1 ? 
ATOM   1025 N N   . ALA A 1 136 ? 3.546  42.831 38.303 1.000 29.242  0 136  ALA A N   1 ? 
ATOM   1026 C CA  . ALA A 1 136 ? 4.438  43.863 37.826 1.000 30.232  0 136  ALA A CA  1 ? 
ATOM   1027 C C   . ALA A 1 136 ? 5.871  43.716 38.352 1.000 28.041  0 136  ALA A C   1 ? 
ATOM   1028 O O   . ALA A 1 136 ? 6.857  43.907 37.628 1.000 28.604  0 136  ALA A O   1 ? 
ATOM   1029 C CB  . ALA A 1 136 ? 3.839  45.184 38.256 1.000 36.621  0 136  ALA A CB  1 ? 
ATOM   1030 N N   . LYS A 1 137 ? 6.029  43.403 39.640 1.000 27.693  0 137  LYS A N   1 ? 
ATOM   1031 C CA  . LYS A 1 137 ? 7.371  43.372 40.185 1.000 25.840  0 137  LYS A CA  1 ? 
ATOM   1032 C C   . LYS A 1 137 ? 8.180  42.172 39.718 1.000 24.857  0 137  LYS A C   1 ? 
ATOM   1033 O O   . LYS A 1 137 ? 9.409  42.167 39.871 1.000 29.316  0 137  LYS A O   1 ? 
ATOM   1034 C CB  . LYS A 1 137 ? 7.297  43.358 41.705 1.000 35.678  0 137  LYS A CB  1 ? 
ATOM   1035 C CG  . LYS A 1 137 ? 6.823  44.703 42.224 1.000 38.407  0 137  LYS A CG  1 ? 
ATOM   1036 C CD  . LYS A 1 137 ? 7.132  44.965 43.642 1.000 52.450  0 137  LYS A CD  1 ? 
ATOM   1037 C CE  . LYS A 1 137 ? 7.202  46.461 43.864 1.000 63.384  0 137  LYS A CE  1 ? 
ATOM   1038 N NZ  . LYS A 1 137 ? 6.745  46.790 45.231 1.000 74.251  0 137  LYS A NZ  1 ? 
ATOM   1039 N N   . LEU A 1 138 ? 7.514  41.160 39.192 1.000 22.992  0 138  LEU A N   1 ? 
ATOM   1040 C CA  . LEU A 1 138 ? 8.263  39.997 38.728 1.000 23.452  0 138  LEU A CA  1 ? 
ATOM   1041 C C   . LEU A 1 138 ? 8.487  39.991 37.215 1.000 22.993  0 138  LEU A C   1 ? 
ATOM   1042 O O   . LEU A 1 138 ? 9.167  39.110 36.709 1.000 25.044  0 138  LEU A O   1 ? 
ATOM   1043 C CB  . LEU A 1 138 ? 7.492  38.735 39.070 1.000 22.265  0 138  LEU A CB  1 ? 
ATOM   1044 C CG  . LEU A 1 138 ? 7.192  38.522 40.545 1.000 22.716  0 138  LEU A CG  1 ? 
ATOM   1045 C CD1 . LEU A 1 138 ? 6.456  37.229 40.679 1.000 25.556  0 138  LEU A CD1 1 ? 
ATOM   1046 C CD2 . LEU A 1 138 ? 8.478  38.527 41.321 1.000 26.992  0 138  LEU A CD2 1 ? 
ATOM   1047 N N   . LYS A 1 139 ? 7.887  40.908 36.473 1.000 21.219  0 139  LYS A N   1 ? 
ATOM   1048 C CA  . LYS A 1 139 ? 8.046  40.894 35.037 1.000 24.915  0 139  LYS A CA  1 ? 
ATOM   1049 C C   . LYS A 1 139 ? 9.499  41.138 34.668 1.000 27.098  0 139  LYS A C   1 ? 
ATOM   1050 O O   . LYS A 1 139 ? 10.134 42.027 35.186 1.000 31.295  0 139  LYS A O   1 ? 
ATOM   1051 C CB  . LYS A 1 139 ? 7.245  41.992 34.365 1.000 31.651  0 139  LYS A CB  1 ? 
ATOM   1052 C CG  . LYS A 1 139 ? 5.749  41.816 34.322 1.000 41.325  0 139  LYS A CG  1 ? 
ATOM   1053 C CD  . LYS A 1 139 ? 5.086  43.013 33.611 1.000 52.359  0 139  LYS A CD  1 ? 
ATOM   1054 C CE  . LYS A 1 139 ? 3.588  42.890 33.452 1.000 62.377  0 139  LYS A CE  1 ? 
ATOM   1055 N NZ  . LYS A 1 139 ? 3.243  41.636 32.728 1.000 69.020  0 139  LYS A NZ  1 ? 
ATOM   1056 N N   . ALA A 1 140 ? 10.034 40.309 33.798 1.000 26.588  0 140  ALA A N   1 ? 
ATOM   1057 C CA  . ALA A 1 140 ? 11.381 40.535 33.318 1.000 31.705  0 140  ALA A CA  1 ? 
ATOM   1058 C C   . ALA A 1 140 ? 11.274 41.305 32.015 1.000 32.343  0 140  ALA A C   1 ? 
ATOM   1059 O O   . ALA A 1 140 ? 10.513 40.893 31.149 1.000 32.514  0 140  ALA A O   1 ? 
ATOM   1060 C CB  . ALA A 1 140 ? 12.071 39.219 33.099 1.000 34.066  0 140  ALA A CB  1 ? 
ATOM   1061 N N   . PRO A 1 141 ? 12.089 42.361 31.830 1.000 39.095  0 141  PRO A N   1 ? 
ATOM   1062 C CA  . PRO A 1 141 ? 12.023 43.203 30.627 1.000 42.121  0 141  PRO A CA  1 ? 
ATOM   1063 C C   . PRO A 1 141 ? 12.283 42.415 29.355 1.000 41.675  0 141  PRO A C   1 ? 
ATOM   1064 O O   . PRO A 1 141 ? 11.547 42.571 28.370 1.000 48.582  0 141  PRO A O   1 ? 
ATOM   1065 C CB  . PRO A 1 141 ? 13.161 44.190 30.877 1.000 40.519  0 141  PRO A CB  1 ? 
ATOM   1066 C CG  . PRO A 1 141 ? 13.247 44.290 32.357 1.000 44.449  0 141  PRO A CG  1 ? 
ATOM   1067 C CD  . PRO A 1 141 ? 13.066 42.861 32.810 1.000 41.500  0 141  PRO A CD  1 ? 
ATOM   1068 N N   . GLY A 1 142 ? 13.269 41.510 29.466 1.000 45.872  0 142  GLY A N   1 ? 
ATOM   1069 C CA  . GLY A 1 142 ? 13.663 40.613 28.390 1.000 45.786  0 142  GLY A CA  1 ? 
ATOM   1070 C C   . GLY A 1 142 ? 12.543 39.672 27.952 1.000 47.840  0 142  GLY A C   1 ? 
ATOM   1071 O O   . GLY A 1 142 ? 12.591 39.055 26.891 1.000 42.728  0 142  GLY A O   1 ? 
ATOM   1072 N N   . GLY A 1 143 ? 11.508 39.541 28.775 1.000 40.941  0 143  GLY A N   1 ? 
ATOM   1073 C CA  . GLY A 1 143 ? 10.445 38.582 28.510 1.000 39.811  0 143  GLY A CA  1 ? 
ATOM   1074 C C   . GLY A 1 143 ? 10.431 37.644 29.715 1.000 35.554  0 143  GLY A C   1 ? 
ATOM   1075 O O   . GLY A 1 143 ? 11.424 37.508 30.454 1.000 37.205  0 143  GLY A O   1 ? 
ATOM   1076 N N   . GLY A 1 144 ? 9.267  37.146 30.035 1.000 30.987  0 144  GLY A N   1 ? 
ATOM   1077 C CA  . GLY A 1 144 ? 9.220  36.176 31.097 1.000 25.005  0 144  GLY A CA  1 ? 
ATOM   1078 C C   . GLY A 1 144 ? 8.786  36.780 32.409 1.000 24.690  0 144  GLY A C   1 ? 
ATOM   1079 O O   . GLY A 1 144 ? 8.589  37.984 32.534 1.000 25.216  0 144  GLY A O   1 ? 
ATOM   1080 N N   . CYS A 1 145 ? 8.571  35.879 33.347 1.000 20.443  0 145  CYS A N   1 ? 
ATOM   1081 C CA  . CYS A 1 145 ? 8.056  36.213 34.661 1.000 20.744  0 145  CYS A CA  1 ? 
ATOM   1082 C C   . CYS A 1 145 ? 9.000  35.598 35.665 1.000 20.644  0 145  CYS A C   1 ? 
ATOM   1083 O O   . CYS A 1 145 ? 9.145  34.389 35.778 1.000 20.378  0 145  CYS A O   1 ? 
ATOM   1084 C CB  . CYS A 1 145 ? 6.655  35.691 34.826 1.000 22.850  0 145  CYS A CB  1 ? 
ATOM   1085 S SG  . CYS A 1 145 ? 5.863  36.244 36.341 1.000 22.945  0 145  CYS A SG  1 ? 
ATOM   1086 N N   . ASN A 1 146 ? 9.738  36.450 36.373 1.000 20.551  0 146  ASN A N   1 ? 
ATOM   1087 C CA  . ASN A 1 146 ? 10.715 35.925 37.296 1.000 21.020  0 146  ASN A CA  1 ? 
ATOM   1088 C C   . ASN A 1 146 ? 10.049 35.401 38.540 1.000 19.880  0 146  ASN A C   1 ? 
ATOM   1089 O O   . ASN A 1 146 ? 8.985  35.843 38.926 1.000 21.614  0 146  ASN A O   1 ? 
ATOM   1090 C CB  . ASN A 1 146 ? 11.639 36.980 37.825 1.000 21.570  0 146  ASN A CB  1 ? 
ATOM   1091 C CG  . ASN A 1 146 ? 12.652 37.461 36.816 1.000 28.831  0 146  ASN A CG  1 ? 
ATOM   1092 O OD1 . ASN A 1 146 ? 13.412 36.670 36.300 1.000 31.306  0 146  ASN A OD1 1 ? 
ATOM   1093 N ND2 . ASN A 1 146 ? 12.706 38.764 36.613 1.000 34.146  0 146  ASN A ND2 1 ? 
ATOM   1094 N N   . ASP A 1 147 ? 10.730 34.459 39.182 1.000 20.140  0 147  ASP A N   1 ? 
ATOM   1095 C CA  . ASP A 1 147 ? 10.328 34.042 40.521 1.000 19.609  0 147  ASP A CA  1 ? 
ATOM   1096 C C   . ASP A 1 147 ? 10.814 35.102 41.516 1.000 19.629  0 147  ASP A C   1 ? 
ATOM   1097 O O   . ASP A 1 147 ? 11.725 35.923 41.263 1.000 19.357  0 147  ASP A O   1 ? 
ATOM   1098 C CB  . ASP A 1 147 ? 11.029 32.749 40.909 1.000 20.782  0 147  ASP A CB  1 ? 
ATOM   1099 C CG  . ASP A 1 147 ? 12.536 32.896 40.948 1.000 23.187  0 147  ASP A CG  1 ? 
ATOM   1100 O OD1 . ASP A 1 147 ? 13.163 32.959 39.882 1.000 20.755  0 147  ASP A OD1 1 ? 
ATOM   1101 O OD2 . ASP A 1 147 ? 13.082 32.997 42.097 1.000 22.991  0 147  ASP A OD2 1 ? 
ATOM   1102 N N   . ALA A 1 148 ? 10.243 35.057 42.711 1.000 18.471  0 148  ALA A N   1 ? 
ATOM   1103 C CA  . ALA A 1 148 ? 10.502 36.090 43.691 1.000 19.468  0 148  ALA A CA  1 ? 
ATOM   1104 C C   . ALA A 1 148 ? 11.874 35.989 44.311 1.000 18.527  0 148  ALA A C   1 ? 
ATOM   1105 O O   . ALA A 1 148 ? 12.375 36.985 44.822 1.000 21.195  0 148  ALA A O   1 ? 
ATOM   1106 C CB  . ALA A 1 148 ? 9.450  35.975 44.803 1.000 20.970  0 148  ALA A CB  1 ? 
ATOM   1107 N N   . CYS A 1 149 ? 12.464 34.809 44.349 1.000 19.619  0 149  CYS A N   1 ? 
ATOM   1108 C CA  . CYS A 1 149 ? 13.789 34.636 44.888 1.000 19.611  0 149  CYS A CA  1 ? 
ATOM   1109 C C   . CYS A 1 149 ? 14.780 35.382 44.003 1.000 22.211  0 149  CYS A C   1 ? 
ATOM   1110 O O   . CYS A 1 149 ? 15.570 36.178 44.481 1.000 21.590  0 149  CYS A O   1 ? 
ATOM   1111 C CB  . CYS A 1 149 ? 14.125 33.158 45.053 1.000 23.059  0 149  CYS A CB  1 ? 
ATOM   1112 S SG  . CYS A 1 149 ? 15.877 32.902 45.407 1.000 23.115  0 149  CYS A SG  1 ? 
ATOM   1113 N N   . THR A 1 150 ? 14.701 35.165 42.695 1.000 20.080  0 150  THR A N   1 ? 
ATOM   1114 C CA  . THR A 1 150 ? 15.535 35.878 41.769 1.000 20.735  0 150  THR A CA  1 ? 
ATOM   1115 C C   . THR A 1 150 ? 15.413 37.380 41.939 1.000 19.612  0 150  THR A C   1 ? 
ATOM   1116 O O   . THR A 1 150 ? 16.404 38.079 41.903 1.000 24.882  0 150  THR A O   1 ? 
ATOM   1117 C CB  . THR A 1 150 ? 15.139 35.486 40.343 1.000 23.381  0 150  THR A CB  1 ? 
ATOM   1118 O OG1 . THR A 1 150 ? 15.465 34.113 40.235 1.000 22.499  0 150  THR A OG1 1 ? 
ATOM   1119 C CG2 . THR A 1 150 ? 15.862 36.278 39.291 1.000 25.956  0 150  THR A CG2 1 ? 
ATOM   1120 N N   . VAL A 1 151 ? 14.199 37.891 42.074 1.000 22.259  0 151  VAL A N   1 ? 
ATOM   1121 C CA  . VAL A 1 151 ? 13.993 39.308 42.131 1.000 20.765  0 151  VAL A CA  1 ? 
ATOM   1122 C C   . VAL A 1 151 ? 14.466 39.901 43.461 1.000 23.812  0 151  VAL A C   1 ? 
ATOM   1123 O O   . VAL A 1 151 ? 15.136 40.920 43.463 1.000 24.235  0 151  VAL A O   1 ? 
ATOM   1124 C CB  . VAL A 1 151 ? 12.525 39.646 41.839 1.000 22.516  0 151  VAL A CB  1 ? 
ATOM   1125 C CG1 . VAL A 1 151 ? 12.194 41.114 41.992 1.000 23.082  0 151  VAL A CG1 1 ? 
ATOM   1126 C CG2 . VAL A 1 151 ? 12.202 39.181 40.442 1.000 24.386  0 151  VAL A CG2 1 ? 
ATOM   1127 N N   . PHE A 1 152 ? 14.057 39.316 44.556 1.000 21.591  0 152  PHE A N   1 ? 
ATOM   1128 C CA  . PHE A 1 152 ? 14.156 39.985 45.857 1.000 22.996  0 152  PHE A CA  1 ? 
ATOM   1129 C C   . PHE A 1 152 ? 15.263 39.449 46.745 1.000 22.674  0 152  PHE A C   1 ? 
ATOM   1130 O O   . PHE A 1 152 ? 15.649 40.110 47.682 1.000 23.433  0 152  PHE A O   1 ? 
ATOM   1131 C CB  . PHE A 1 152 ? 12.838 39.857 46.589 1.000 21.858  0 152  PHE A CB  1 ? 
ATOM   1132 C CG  . PHE A 1 152 ? 11.771 40.679 45.973 1.000 21.627  0 152  PHE A CG  1 ? 
ATOM   1133 C CD1 . PHE A 1 152 ? 11.792 42.058 46.072 1.000 24.798  0 152  PHE A CD1 1 ? 
ATOM   1134 C CD2 . PHE A 1 152 ? 10.780 40.082 45.238 1.000 23.304  0 152  PHE A CD2 1 ? 
ATOM   1135 C CE1 . PHE A 1 152 ? 10.769 42.803 45.499 1.000 25.660  0 152  PHE A CE1 1 ? 
ATOM   1136 C CE2 . PHE A 1 152 ? 9.769  40.825 44.676 1.000 26.253  0 152  PHE A CE2 1 ? 
ATOM   1137 C CZ  . PHE A 1 152 ? 9.808  42.175 44.759 1.000 24.719  0 152  PHE A CZ  1 ? 
ATOM   1138 N N   . GLN A 1 153 ? 15.714 38.215 46.501 1.000 21.105  0 153  GLN A N   1 ? 
ATOM   1139 C CA  A GLN A 1 153 ? 16.864 37.659 47.191 0.700 20.999  0 153  GLN A CA  1 ? 
ATOM   1140 C CA  B GLN A 1 153 ? 16.809 37.571 47.204 0.300 21.550  0 153  GLN A CA  1 ? 
ATOM   1141 C C   . GLN A 1 153 ? 16.658 37.700 48.707 1.000 21.774  0 153  GLN A C   1 ? 
ATOM   1142 O O   . GLN A 1 153 ? 17.567 38.115 49.421 1.000 22.362  0 153  GLN A O   1 ? 
ATOM   1143 C CB  A GLN A 1 153 ? 18.145 38.434 46.813 0.700 20.566  0 153  GLN A CB  1 ? 
ATOM   1144 C CB  B GLN A 1 153 ? 18.136 38.135 46.729 0.300 22.442  0 153  GLN A CB  1 ? 
ATOM   1145 C CG  A GLN A 1 153 ? 18.579 38.264 45.343 0.700 25.132  0 153  GLN A CG  1 ? 
ATOM   1146 C CG  B GLN A 1 153 ? 18.455 37.601 45.354 0.300 24.366  0 153  GLN A CG  1 ? 
ATOM   1147 C CD  A GLN A 1 153 ? 19.203 36.906 45.069 0.700 28.434  0 153  GLN A CD  1 ? 
ATOM   1148 C CD  B GLN A 1 153 ? 19.615 38.377 44.825 0.300 24.691  0 153  GLN A CD  1 ? 
ATOM   1149 O OE1 A GLN A 1 153 ? 20.389 36.686 45.243 0.700 27.000  0 153  GLN A OE1 1 ? 
ATOM   1150 O OE1 B GLN A 1 153 ? 19.519 39.571 44.542 0.300 29.711  0 153  GLN A OE1 1 ? 
ATOM   1151 N NE2 A GLN A 1 153 ? 18.441 35.940 44.597 0.700 32.195  0 153  GLN A NE2 1 ? 
ATOM   1152 N NE2 B GLN A 1 153 ? 20.733 37.691 44.747 0.300 24.752  0 153  GLN A NE2 1 ? 
ATOM   1153 N N   . THR A 1 154 ? 15.514 37.247 49.193 1.000 18.780  0 154  THR A N   1 ? 
ATOM   1154 C CA  . THR A 1 154 ? 15.278 37.122 50.618 1.000 19.864  0 154  THR A CA  1 ? 
ATOM   1155 C C   . THR A 1 154 ? 15.318 35.647 51.019 1.000 20.781  0 154  THR A C   1 ? 
ATOM   1156 O O   . THR A 1 154 ? 15.079 34.735 50.234 1.000 22.096  0 154  THR A O   1 ? 
ATOM   1157 C CB  . THR A 1 154 ? 13.953 37.724 51.044 1.000 22.021  0 154  THR A CB  1 ? 
ATOM   1158 O OG1 . THR A 1 154 ? 12.931 36.866 50.558 1.000 21.690  0 154  THR A OG1 1 ? 
ATOM   1159 C CG2 . THR A 1 154 ? 13.760 39.142 50.593 1.000 25.898  0 154  THR A CG2 1 ? 
ATOM   1160 N N   . SER A 1 155 ? 15.561 35.431 52.313 1.000 20.536  0 155  SER A N   1 ? 
ATOM   1161 C CA  A SER A 1 155 ? 15.579 34.089 52.870 0.700 20.859  0 155  SER A CA  1 ? 
ATOM   1162 C CA  B SER A 1 155 ? 15.560 34.109 52.916 0.300 20.372  0 155  SER A CA  1 ? 
ATOM   1163 C C   . SER A 1 155 ? 14.221 33.421 52.676 1.000 20.781  0 155  SER A C   1 ? 
ATOM   1164 O O   . SER A 1 155 ? 14.168 32.255 52.409 1.000 21.952  0 155  SER A O   1 ? 
ATOM   1165 C CB  A SER A 1 155 ? 16.002 34.055 54.314 0.700 23.587  0 155  SER A CB  1 ? 
ATOM   1166 C CB  B SER A 1 155 ? 15.864 34.181 54.391 0.300 21.058  0 155  SER A CB  1 ? 
ATOM   1167 O OG  A SER A 1 155 ? 17.325 34.567 54.463 0.700 28.405  0 155  SER A OG  1 ? 
ATOM   1168 O OG  B SER A 1 155 ? 14.881 34.937 55.093 0.300 21.744  0 155  SER A OG  1 ? 
ATOM   1169 N N   . GLU A 1 156 ? 13.138 34.189 52.764 1.000 20.023  0 156  GLU A N   1 ? 
ATOM   1170 C CA  . GLU A 1 156 ? 11.821 33.642 52.618 1.000 19.649  0 156  GLU A CA  1 ? 
ATOM   1171 C C   . GLU A 1 156 ? 11.551 33.169 51.205 1.000 21.412  0 156  GLU A C   1 ? 
ATOM   1172 O O   . GLU A 1 156 ? 11.094 32.062 51.059 1.000 22.768  0 156  GLU A O   1 ? 
ATOM   1173 C CB  . GLU A 1 156 ? 10.770 34.649 53.023 1.000 21.948  0 156  GLU A CB  1 ? 
ATOM   1174 C CG  . GLU A 1 156 ? 9.406  34.018 53.270 1.000 20.545  0 156  GLU A CG  1 ? 
ATOM   1175 C CD  . GLU A 1 156 ? 9.341  32.942 54.335 1.000 24.025  0 156  GLU A CD  1 ? 
ATOM   1176 O OE1 . GLU A 1 156 ? 10.272 32.825 55.162 1.000 23.634  0 156  GLU A OE1 1 ? 
ATOM   1177 O OE2 . GLU A 1 156 ? 8.361  32.196 54.372 1.000 25.708  0 156  GLU A OE2 1 ? 
ATOM   1178 N N   . TYR A 1 157 ? 11.854 33.997 50.221 1.000 20.747  0 157  TYR A N   1 ? 
ATOM   1179 C CA  . TYR A 1 157 ? 11.569 33.563 48.856 1.000 20.057  0 157  TYR A CA  1 ? 
ATOM   1180 C C   . TYR A 1 157 ? 12.506 32.468 48.401 1.000 22.241  0 157  TYR A C   1 ? 
ATOM   1181 O O   . TYR A 1 157 ? 12.118 31.646 47.592 1.000 21.630  0 157  TYR A O   1 ? 
ATOM   1182 C CB  . TYR A 1 157 ? 11.691 34.736 47.902 1.000 18.725  0 157  TYR A CB  1 ? 
ATOM   1183 C CG  . TYR A 1 157 ? 10.666 35.812 48.128 1.000 19.334  0 157  TYR A CG  1 ? 
ATOM   1184 C CD1 . TYR A 1 157 ? 9.347  35.513 48.373 1.000 21.987  0 157  TYR A CD1 1 ? 
ATOM   1185 C CD2 . TYR A 1 157 ? 11.015 37.134 48.086 1.000 19.418  0 157  TYR A CD2 1 ? 
ATOM   1186 C CE1 . TYR A 1 157 ? 8.411  36.495 48.609 1.000 21.450  0 157  TYR A CE1 1 ? 
ATOM   1187 C CE2 . TYR A 1 157 ? 10.095 38.130 48.299 1.000 21.312  0 157  TYR A CE2 1 ? 
ATOM   1188 C CZ  . TYR A 1 157 ? 8.801  37.809 48.611 1.000 20.075  0 157  TYR A CZ  1 ? 
ATOM   1189 O OH  . TYR A 1 157 ? 7.886  38.787 48.833 1.000 22.502  0 157  TYR A OH  1 ? 
ATOM   1190 N N   . CYS A 1 158 ? 13.760 32.551 48.833 1.000 21.164  0 158  CYS A N   1 ? 
ATOM   1191 C CA  . CYS A 1 158 ? 14.778 31.615 48.394 1.000 21.501  0 158  CYS A CA  1 ? 
ATOM   1192 C C   . CYS A 1 158 ? 14.832 30.368 49.255 1.000 23.401  0 158  CYS A C   1 ? 
ATOM   1193 O O   . CYS A 1 158 ? 15.465 29.402 48.838 1.000 25.266  0 158  CYS A O   1 ? 
ATOM   1194 C CB  . CYS A 1 158 ? 16.131 32.279 48.312 1.000 20.717  0 158  CYS A CB  1 ? 
ATOM   1195 S SG  . CYS A 1 158 ? 16.114 33.727 47.242 1.000 22.229  0 158  CYS A SG  1 ? 
ATOM   1196 N N   . CYS A 1 159 ? 14.102 30.377 50.372 1.000 23.345  0 159  CYS A N   1 ? 
ATOM   1197 C CA  A CYS A 1 159 ? 14.004 29.274 51.287 0.500 24.047  0 159  CYS A CA  1 ? 
ATOM   1198 C CA  B CYS A 1 159 ? 14.000 29.258 51.293 0.500 25.163  0 159  CYS A CA  1 ? 
ATOM   1199 C C   . CYS A 1 159 ? 15.378 28.862 51.785 1.000 26.410  0 159  CYS A C   1 ? 
ATOM   1200 O O   . CYS A 1 159 ? 15.689 27.695 51.972 1.000 26.919  0 159  CYS A O   1 ? 
ATOM   1201 C CB  A CYS A 1 159 ? 13.272 28.126 50.638 0.500 25.519  0 159  CYS A CB  1 ? 
ATOM   1202 C CB  B CYS A 1 159 ? 13.322 28.043 50.685 0.500 28.268  0 159  CYS A CB  1 ? 
ATOM   1203 S SG  A CYS A 1 159 ? 12.379 27.234 51.911 0.500 22.729  0 159  CYS A SG  1 ? 
ATOM   1204 S SG  B CYS A 1 159 ? 11.598 28.359 50.252 0.500 29.275  0 159  CYS A SG  1 ? 
ATOM   1205 N N   . THR A 1 160 ? 16.167 29.869 52.096 1.000 27.625  0 160  THR A N   1 ? 
ATOM   1206 C CA  . THR A 1 160 ? 17.562 29.726 52.424 1.000 27.391  0 160  THR A CA  1 ? 
ATOM   1207 C C   . THR A 1 160 ? 17.763 28.912 53.696 1.000 31.999  0 160  THR A C   1 ? 
ATOM   1208 O O   . THR A 1 160 ? 18.744 28.182 53.755 1.000 37.649  0 160  THR A O   1 ? 
ATOM   1209 C CB  . THR A 1 160 ? 18.164 31.121 52.624 1.000 29.381  0 160  THR A CB  1 ? 
ATOM   1210 O OG1 . THR A 1 160 ? 17.917 31.779 51.392 1.000 34.379  0 160  THR A OG1 1 ? 
ATOM   1211 C CG2 . THR A 1 160 ? 19.647 31.101 52.889 1.000 41.779  0 160  THR A CG2 1 ? 
ATOM   1212 N N   . THR A 1 161 ? 16.881 29.086 54.677 1.000 30.395  0 161  THR A N   1 ? 
ATOM   1213 C CA  . THR A 1 161 ? 17.019 28.418 55.964 1.000 36.049  0 161  THR A CA  1 ? 
ATOM   1214 C C   . THR A 1 161 ? 16.403 27.030 55.916 1.000 40.818  0 161  THR A C   1 ? 
ATOM   1215 O O   . THR A 1 161 ? 16.508 26.299 56.887 1.000 41.767  0 161  THR A O   1 ? 
ATOM   1216 C CB  . THR A 1 161 ? 16.351 29.209 57.091 1.000 35.330  0 161  THR A CB  1 ? 
ATOM   1217 O OG1 . THR A 1 161 ? 14.943 29.095 56.932 1.000 37.658  0 161  THR A OG1 1 ? 
ATOM   1218 C CG2 . THR A 1 161 ? 16.727 30.679 57.116 1.000 40.005  0 161  THR A CG2 1 ? 
ATOM   1219 N N   . GLY A 1 162 ? 15.745 26.670 54.811 1.000 38.775  0 162  GLY A N   1 ? 
ATOM   1220 C CA  . GLY A 1 162 ? 15.059 25.399 54.722 1.000 37.964  0 162  GLY A CA  1 ? 
ATOM   1221 C C   . GLY A 1 162 ? 13.692 25.471 55.390 1.000 37.462  0 162  GLY A C   1 ? 
ATOM   1222 O O   . GLY A 1 162 ? 12.934 24.518 55.364 1.000 38.903  0 162  GLY A O   1 ? 
ATOM   1223 N N   . LYS A 1 163 ? 13.350 26.634 55.945 1.000 36.255  0 163  LYS A N   1 ? 
ATOM   1224 C CA  . LYS A 1 163 ? 12.032 26.913 56.461 1.000 41.114  0 163  LYS A CA  1 ? 
ATOM   1225 C C   . LYS A 1 163 ? 11.540 28.073 55.620 1.000 37.616  0 163  LYS A C   1 ? 
ATOM   1226 O O   . LYS A 1 163 ? 12.193 29.087 55.525 1.000 42.356  0 163  LYS A O   1 ? 
ATOM   1227 C CB  . LYS A 1 163 ? 12.056 27.362 57.925 1.000 52.175  0 163  LYS A CB  1 ? 
ATOM   1228 C CG  . LYS A 1 163 ? 12.544 26.312 58.917 1.000 64.096  0 163  LYS A CG  1 ? 
ATOM   1229 C CD  . LYS A 1 163 ? 11.454 25.327 59.339 1.000 77.658  0 163  LYS A CD  1 ? 
ATOM   1230 C CE  . LYS A 1 163 ? 11.975 24.061 59.987 1.000 88.379  0 163  LYS A CE  1 ? 
ATOM   1231 N NZ  . LYS A 1 163 ? 13.118 24.343 60.888 1.000 97.105  0 163  LYS A NZ  1 ? 
ATOM   1232 N N   . CYS A 1 164 ? 10.422 27.895 54.964 1.000 30.341  0 164  CYS A N   1 ? 
ATOM   1233 C CA  . CYS A 1 164 ? 9.820  29.015 54.275 1.000 25.949  0 164  CYS A CA  1 ? 
ATOM   1234 C C   . CYS A 1 164 ? 8.419  28.561 53.970 1.000 28.286  0 164  CYS A C   1 ? 
ATOM   1235 O O   . CYS A 1 164 ? 8.141  27.382 54.003 1.000 31.205  0 164  CYS A O   1 ? 
ATOM   1236 C CB  . CYS A 1 164 ? 10.485 29.371 52.954 1.000 26.813  0 164  CYS A CB  1 ? 
ATOM   1237 S SG  . CYS A 1 164 ? 10.569 27.995 51.792 1.000 29.381  0 164  CYS A SG  1 ? 
ATOM   1238 N N   . GLY A 1 165 ? 7.554  29.520 53.690 1.000 24.795  0 165  GLY A N   1 ? 
ATOM   1239 C CA  . GLY A 1 165 ? 6.191  29.208 53.368 1.000 24.870  0 165  GLY A CA  1 ? 
ATOM   1240 C C   . GLY A 1 165 ? 5.896  29.713 51.977 1.000 24.694  0 165  GLY A C   1 ? 
ATOM   1241 O O   . GLY A 1 165 ? 6.693  30.439 51.392 1.000 23.947  0 165  GLY A O   1 ? 
ATOM   1242 N N   . PRO A 1 166 ? 4.677  29.439 51.511 1.000 23.232  0 166  PRO A N   1 ? 
ATOM   1243 C CA  . PRO A 1 166 ? 4.204  30.018 50.275 1.000 21.730  0 166  PRO A CA  1 ? 
ATOM   1244 C C   . PRO A 1 166 ? 4.143  31.525 50.486 1.000 23.218  0 166  PRO A C   1 ? 
ATOM   1245 O O   . PRO A 1 166 ? 3.988  31.965 51.613 1.000 21.863  0 166  PRO A O   1 ? 
ATOM   1246 C CB  . PRO A 1 166 ? 2.815  29.396 50.079 1.000 24.592  0 166  PRO A CB  1 ? 
ATOM   1247 C CG  . PRO A 1 166 ? 2.483  28.680 51.366 1.000 28.631  0 166  PRO A CG  1 ? 
ATOM   1248 C CD  . PRO A 1 166 ? 3.678  28.682 52.263 1.000 26.429  0 166  PRO A CD  1 ? 
ATOM   1249 N N   . THR A 1 167 ? 4.118  32.273 49.395 1.000 21.911  0 167  THR A N   1 ? 
ATOM   1250 C CA  . THR A 1 167 ? 4.112  33.722 49.393 1.000 22.136  0 167  THR A CA  1 ? 
ATOM   1251 C C   . THR A 1 167 ? 3.080  34.172 48.394 1.000 21.710  0 167  THR A C   1 ? 
ATOM   1252 O O   . THR A 1 167 ? 2.598  33.389 47.562 1.000 22.323  0 167  THR A O   1 ? 
ATOM   1253 C CB  . THR A 1 167 ? 5.510  34.273 49.072 1.000 21.157  0 167  THR A CB  1 ? 
ATOM   1254 O OG1 . THR A 1 167 ? 5.765  33.909 47.707 1.000 20.154  0 167  THR A OG1 1 ? 
ATOM   1255 C CG2 . THR A 1 167 ? 6.570  33.670 49.978 1.000 20.718  0 167  THR A CG2 1 ? 
ATOM   1256 N N   . GLU A 1 168 ? 2.799  35.463 48.407 1.000 20.800  0 168  GLU A N   1 ? 
ATOM   1257 C CA  . GLU A 1 168 ? 1.908  35.993 47.396 1.000 23.998  0 168  GLU A CA  1 ? 
ATOM   1258 C C   . GLU A 1 168 ? 2.437  35.606 46.021 1.000 21.800  0 168  GLU A C   1 ? 
ATOM   1259 O O   . GLU A 1 168 ? 1.663  35.354 45.097 1.000 23.008  0 168  GLU A O   1 ? 
ATOM   1260 C CB  . GLU A 1 168 ? 1.758  37.504 47.468 1.000 29.718  0 168  GLU A CB  1 ? 
ATOM   1261 C CG  . GLU A 1 168 ? 0.677  37.932 48.466 1.000 45.376  0 168  GLU A CG  1 ? 
ATOM   1262 C CD  . GLU A 1 168 ? -0.673 37.219 48.299 1.000 46.473  0 168  GLU A CD  1 ? 
ATOM   1263 O OE1 . GLU A 1 168 ? -0.950 36.104 48.997 1.000 43.150  0 168  GLU A OE1 1 ? 
ATOM   1264 O OE2 . GLU A 1 168 ? -1.408 37.685 47.406 1.000 56.958  0 168  GLU A OE2 1 ? 
ATOM   1265 N N   . TYR A 1 169 ? 3.750  35.682 45.877 1.000 20.729  0 169  TYR A N   1 ? 
ATOM   1266 C CA  . TYR A 1 169 ? 4.331  35.452 44.570 1.000 21.456  0 169  TYR A CA  1 ? 
ATOM   1267 C C   . TYR A 1 169 ? 4.299  33.992 44.188 1.000 21.396  0 169  TYR A C   1 ? 
ATOM   1268 O O   . TYR A 1 169 ? 3.931  33.681 43.061 1.000 22.597  0 169  TYR A O   1 ? 
ATOM   1269 C CB  . TYR A 1 169 ? 5.731  35.989 44.492 1.000 20.515  0 169  TYR A CB  1 ? 
ATOM   1270 C CG  . TYR A 1 169 ? 5.797  37.480 44.633 1.000 20.451  0 169  TYR A CG  1 ? 
ATOM   1271 C CD1 . TYR A 1 169 ? 5.109  38.320 43.780 1.000 23.011  0 169  TYR A CD1 1 ? 
ATOM   1272 C CD2 . TYR A 1 169 ? 6.565  38.044 45.625 1.000 20.615  0 169  TYR A CD2 1 ? 
ATOM   1273 C CE1 . TYR A 1 169 ? 5.211  39.685 43.903 1.000 24.576  0 169  TYR A CE1 1 ? 
ATOM   1274 C CE2 . TYR A 1 169 ? 6.683  39.413 45.768 1.000 22.251  0 169  TYR A CE2 1 ? 
ATOM   1275 C CZ  . TYR A 1 169 ? 5.972  40.234 44.912 1.000 25.816  0 169  TYR A CZ  1 ? 
ATOM   1276 O OH  . TYR A 1 169 ? 6.080  41.585 45.059 1.000 25.869  0 169  TYR A OH  1 ? 
ATOM   1277 N N   . SER A 1 170 ? 4.594  33.101 45.126 1.000 21.142  0 170  SER A N   1 ? 
ATOM   1278 C CA  . SER A 1 170 ? 4.539  31.684 44.818 1.000 21.486  0 170  SER A CA  1 ? 
ATOM   1279 C C   . SER A 1 170 ? 3.110  31.273 44.500 1.000 22.416  0 170  SER A C   1 ? 
ATOM   1280 O O   . SER A 1 170 ? 2.893  30.487 43.584 1.000 22.680  0 170  SER A O   1 ? 
ATOM   1281 C CB  . SER A 1 170 ? 5.144  30.837 45.873 1.000 21.801  0 170  SER A CB  1 ? 
ATOM   1282 O OG  . SER A 1 170 ? 4.322  30.682 46.996 1.000 22.374  0 170  SER A OG  1 ? 
ATOM   1283 N N   . ARG A 1 171 ? 2.131  31.911 45.155 1.000 20.061  0 171  ARG A N   1 ? 
ATOM   1284 C CA  . ARG A 1 171 ? 0.746  31.525 44.948 1.000 21.347  0 171  ARG A CA  1 ? 
ATOM   1285 C C   . ARG A 1 171 ? 0.268  31.940 43.569 1.000 20.853  0 171  ARG A C   1 ? 
ATOM   1286 O O   . ARG A 1 171 ? -0.654 31.298 43.024 1.000 23.992  0 171  ARG A O   1 ? 
ATOM   1287 C CB  . ARG A 1 171 ? -0.143 32.126 46.043 1.000 21.075  0 171  ARG A CB  1 ? 
ATOM   1288 C CG  . ARG A 1 171 ? -0.012 31.426 47.379 1.000 24.785  0 171  ARG A CG  1 ? 
ATOM   1289 C CD  . ARG A 1 171 ? -0.975 32.151 48.334 1.000 27.952  0 171  ARG A CD  1 ? 
ATOM   1290 N NE  . ARG A 1 171 ? -0.778 31.651 49.657 1.000 31.122  0 171  ARG A NE  1 ? 
ATOM   1291 C CZ  . ARG A 1 171 ? -0.005 32.215 50.587 1.000 30.173  0 171  ARG A CZ  1 ? 
ATOM   1292 N NH1 . ARG A 1 171 ? 0.553  33.400 50.412 1.000 34.031  0 171  ARG A NH1 1 ? 
ATOM   1293 N NH2 . ARG A 1 171 ? 0.133  31.585 51.732 1.000 34.658  0 171  ARG A NH2 1 ? 
ATOM   1294 N N   . PHE A 1 172 ? 0.864  32.968 43.005 1.000 21.131  0 172  PHE A N   1 ? 
ATOM   1295 C CA  . PHE A 1 172 ? 0.534  33.394 41.667 1.000 22.714  0 172  PHE A CA  1 ? 
ATOM   1296 C C   . PHE A 1 172 ? 0.871  32.247 40.713 1.000 23.266  0 172  PHE A C   1 ? 
ATOM   1297 O O   . PHE A 1 172 ? 0.052  31.869 39.872 1.000 22.818  0 172  PHE A O   1 ? 
ATOM   1298 C CB  . PHE A 1 172 ? 1.225  34.717 41.334 1.000 23.987  0 172  PHE A CB  1 ? 
ATOM   1299 C CG  . PHE A 1 172 ? 1.381  34.927 39.858 1.000 21.601  0 172  PHE A CG  1 ? 
ATOM   1300 C CD1 . PHE A 1 172 ? 0.264  35.250 39.115 1.000 24.960  0 172  PHE A CD1 1 ? 
ATOM   1301 C CD2 . PHE A 1 172 ? 2.582  34.653 39.206 1.000 23.621  0 172  PHE A CD2 1 ? 
ATOM   1302 C CE1 . PHE A 1 172 ? 0.338  35.391 37.740 1.000 26.924  0 172  PHE A CE1 1 ? 
ATOM   1303 C CE2 . PHE A 1 172 ? 2.650  34.775 37.822 1.000 24.866  0 172  PHE A CE2 1 ? 
ATOM   1304 C CZ  . PHE A 1 172 ? 1.533  35.140 37.094 1.000 26.205  0 172  PHE A CZ  1 ? 
ATOM   1305 N N   . PHE A 1 173 ? 2.103  31.724 40.826 1.000 21.771  0 173  PHE A N   1 ? 
ATOM   1306 C CA  . PHE A 1 173 ? 2.525  30.685 39.902 1.000 21.073  0 173  PHE A CA  1 ? 
ATOM   1307 C C   . PHE A 1 173 ? 1.695  29.440 40.137 1.000 22.096  0 173  PHE A C   1 ? 
ATOM   1308 O O   . PHE A 1 173 ? 1.378  28.722 39.216 1.000 23.951  0 173  PHE A O   1 ? 
ATOM   1309 C CB  . PHE A 1 173 ? 4.003  30.364 40.085 1.000 19.929  0 173  PHE A CB  1 ? 
ATOM   1310 C CG  . PHE A 1 173 ? 4.945  31.396 39.562 1.000 20.063  0 173  PHE A CG  1 ? 
ATOM   1311 C CD1 . PHE A 1 173 ? 5.349  31.382 38.248 1.000 22.861  0 173  PHE A CD1 1 ? 
ATOM   1312 C CD2 . PHE A 1 173 ? 5.438  32.412 40.393 1.000 22.193  0 173  PHE A CD2 1 ? 
ATOM   1313 C CE1 . PHE A 1 173 ? 6.175  32.379 37.765 1.000 24.089  0 173  PHE A CE1 1 ? 
ATOM   1314 C CE2 . PHE A 1 173 ? 6.267  33.388 39.910 1.000 23.166  0 173  PHE A CE2 1 ? 
ATOM   1315 C CZ  . PHE A 1 173 ? 6.647  33.355 38.582 1.000 25.363  0 173  PHE A CZ  1 ? 
ATOM   1316 N N   . LYS A 1 174 ? 1.367  29.185 41.374 1.000 21.490  0 174  LYS A N   1 ? 
ATOM   1317 C CA  . LYS A 1 174 ? 0.661  27.964 41.731 1.000 21.705  0 174  LYS A CA  1 ? 
ATOM   1318 C C   . LYS A 1 174 ? -0.784 28.022 41.274 1.000 22.918  0 174  LYS A C   1 ? 
ATOM   1319 O O   . LYS A 1 174 ? -1.326 27.027 40.837 1.000 25.545  0 174  LYS A O   1 ? 
ATOM   1320 C CB  . LYS A 1 174 ? 0.746  27.713 43.224 1.000 22.532  0 174  LYS A CB  1 ? 
ATOM   1321 C CG  . LYS A 1 174 ? 0.382  26.314 43.677 1.000 25.637  0 174  LYS A CG  1 ? 
ATOM   1322 C CD  . LYS A 1 174 ? 1.299  25.329 43.135 1.000 27.871  0 174  LYS A CD  1 ? 
ATOM   1323 C CE  . LYS A 1 174 ? 1.179  23.973 43.780 1.000 30.817  0 174  LYS A CE  1 ? 
ATOM   1324 N NZ  . LYS A 1 174 ? 2.268  23.148 43.251 1.000 29.267  0 174  LYS A NZ  1 ? 
ATOM   1325 N N   . ARG A 1 175 ? -1.365 29.205 41.290 1.000 23.449  0 175  ARG A N   1 ? 
ATOM   1326 C CA  . ARG A 1 175 ? -2.739 29.337 40.839 1.000 26.446  0 175  ARG A CA  1 ? 
ATOM   1327 C C   . ARG A 1 175 ? -2.822 29.056 39.345 1.000 27.899  0 175  ARG A C   1 ? 
ATOM   1328 O O   . ARG A 1 175 ? -3.754 28.399 38.914 1.000 27.701  0 175  ARG A O   1 ? 
ATOM   1329 C CB  . ARG A 1 175 ? -3.181 30.751 41.176 1.000 28.591  0 175  ARG A CB  1 ? 
ATOM   1330 C CG  . ARG A 1 175 ? -4.529 31.141 40.624 1.000 33.490  0 175  ARG A CG  1 ? 
ATOM   1331 C CD  . ARG A 1 175 ? -4.999 32.475 41.184 1.000 35.717  0 175  ARG A CD  1 ? 
ATOM   1332 N NE  . ARG A 1 175 ? -4.195 33.662 40.839 1.000 41.430  0 175  ARG A NE  1 ? 
ATOM   1333 C CZ  . ARG A 1 175 ? -4.274 34.330 39.687 1.000 43.681  0 175  ARG A CZ  1 ? 
ATOM   1334 N NH1 . ARG A 1 175 ? -5.071 33.890 38.728 1.000 46.958  0 175  ARG A NH1 1 ? 
ATOM   1335 N NH2 . ARG A 1 175 ? -3.577 35.438 39.497 1.000 40.814  0 175  ARG A NH2 1 ? 
ATOM   1336 N N   . LEU A 1 176 ? -1.879 29.574 38.565 1.000 25.212  0 176  LEU A N   1 ? 
ATOM   1337 C CA  . LEU A 1 176 ? -1.880 29.406 37.114 1.000 24.603  0 176  LEU A CA  1 ? 
ATOM   1338 C C   . LEU A 1 176 ? -1.404 28.022 36.678 1.000 27.258  0 176  LEU A C   1 ? 
ATOM   1339 O O   . LEU A 1 176 ? -1.934 27.476 35.682 1.000 25.446  0 176  LEU A O   1 ? 
ATOM   1340 C CB  . LEU A 1 176 ? -1.072 30.531 36.480 1.000 28.861  0 176  LEU A CB  1 ? 
ATOM   1341 C CG  . LEU A 1 176 ? -1.776 31.888 36.527 1.000 36.624  0 176  LEU A CG  1 ? 
ATOM   1342 C CD1 . LEU A 1 176 ? -1.105 32.863 35.596 1.000 38.825  0 176  LEU A CD1 1 ? 
ATOM   1343 C CD2 . LEU A 1 176 ? -3.230 31.769 36.142 1.000 43.523  0 176  LEU A CD2 1 ? 
ATOM   1344 N N   . CYS A 1 177 ? -0.454 27.455 37.420 1.000 23.908  0 177  CYS A N   1 ? 
ATOM   1345 C CA  . CYS A 1 177 ? 0.121  26.156 37.114 1.000 25.538  0 177  CYS A CA  1 ? 
ATOM   1346 C C   . CYS A 1 177 ? 0.263  25.308 38.368 1.000 26.430  0 177  CYS A C   1 ? 
ATOM   1347 O O   . CYS A 1 177 ? 1.314  25.211 38.992 1.000 23.554  0 177  CYS A O   1 ? 
ATOM   1348 C CB  . CYS A 1 177 ? 1.483  26.370 36.493 1.000 24.782  0 177  CYS A CB  1 ? 
ATOM   1349 S SG  . CYS A 1 177 ? 1.253  26.795 34.759 1.000 24.948  0 177  CYS A SG  1 ? 
ATOM   1350 N N   . PRO A 1 178 ? -0.827 24.681 38.801 1.000 24.437  0 178  PRO A N   1 ? 
ATOM   1351 C CA  . PRO A 1 178 ? -0.833 23.906 40.015 1.000 26.484  0 178  PRO A CA  1 ? 
ATOM   1352 C C   . PRO A 1 178 ? 0.066  22.687 39.952 1.000 25.288  0 178  PRO A C   1 ? 
ATOM   1353 O O   . PRO A 1 178 ? 0.532  22.244 40.967 1.000 26.345  0 178  PRO A O   1 ? 
ATOM   1354 C CB  . PRO A 1 178 ? -2.300 23.475 40.213 1.000 30.916  0 178  PRO A CB  1 ? 
ATOM   1355 C CG  . PRO A 1 178 ? -3.024 23.905 38.995 1.000 31.727  0 178  PRO A CG  1 ? 
ATOM   1356 C CD  . PRO A 1 178 ? -2.164 24.853 38.210 1.000 29.377  0 178  PRO A CD  1 ? 
ATOM   1357 N N   . ASP A 1 179 ? 0.370  22.209 38.748 1.000 26.142  0 179  ASP A N   1 ? 
ATOM   1358 C CA  . ASP A 1 179 ? 1.150  21.001 38.646 1.000 29.773  0 179  ASP A CA  1 ? 
ATOM   1359 C C   . ASP A 1 179 ? 2.634  21.287 38.552 1.000 30.159  0 179  ASP A C   1 ? 
ATOM   1360 O O   . ASP A 1 179 ? 3.381  20.379 38.305 1.000 32.992  0 179  ASP A O   1 ? 
ATOM   1361 C CB  . ASP A 1 179 ? 0.724  20.179 37.438 1.000 37.607  0 179  ASP A CB  1 ? 
ATOM   1362 C CG  . ASP A 1 179 ? -0.641 19.547 37.662 1.000 41.878  0 179  ASP A CG  1 ? 
ATOM   1363 O OD1 . ASP A 1 179 ? -0.970 19.182 38.842 1.000 49.496  0 179  ASP A OD1 1 ? 
ATOM   1364 O OD2 . ASP A 1 179 ? -1.380 19.463 36.703 1.000 46.619  0 179  ASP A OD2 1 ? 
ATOM   1365 N N   . ALA A 1 180 ? 3.061  22.528 38.737 1.000 24.734  0 180  ALA A N   1 ? 
ATOM   1366 C CA  . ALA A 1 180 ? 4.472  22.854 38.721 1.000 22.687  0 180  ALA A CA  1 ? 
ATOM   1367 C C   . ALA A 1 180 ? 4.877  23.315 40.109 1.000 23.299  0 180  ALA A C   1 ? 
ATOM   1368 O O   . ALA A 1 180 ? 4.108  23.980 40.756 1.000 23.477  0 180  ALA A O   1 ? 
ATOM   1369 C CB  . ALA A 1 180 ? 4.763  23.968 37.770 1.000 23.541  0 180  ALA A CB  1 ? 
ATOM   1370 N N   . PHE A 1 181 ? 6.125  23.092 40.471 1.000 23.013  0 181  PHE A N   1 ? 
ATOM   1371 C CA  . PHE A 1 181 ? 6.623  23.627 41.724 1.000 22.862  0 181  PHE A CA  1 ? 
ATOM   1372 C C   . PHE A 1 181 ? 6.613  25.148 41.700 1.000 21.666  0 181  PHE A C   1 ? 
ATOM   1373 O O   . PHE A 1 181 ? 7.093  25.742 40.758 1.000 22.145  0 181  PHE A O   1 ? 
ATOM   1374 C CB  . PHE A 1 181 ? 8.069  23.256 41.923 1.000 25.115  0 181  PHE A CB  1 ? 
ATOM   1375 C CG  . PHE A 1 181 ? 8.284  21.876 42.450 1.000 26.930  0 181  PHE A CG  1 ? 
ATOM   1376 C CD1 . PHE A 1 181 ? 8.293  20.792 41.592 1.000 29.523  0 181  PHE A CD1 1 ? 
ATOM   1377 C CD2 . PHE A 1 181 ? 8.405  21.655 43.803 1.000 30.737  0 181  PHE A CD2 1 ? 
ATOM   1378 C CE1 . PHE A 1 181 ? 8.472  19.503 42.076 1.000 33.881  0 181  PHE A CE1 1 ? 
ATOM   1379 C CE2 . PHE A 1 181 ? 8.606  20.372 44.282 1.000 31.074  0 181  PHE A CE2 1 ? 
ATOM   1380 C CZ  . PHE A 1 181 ? 8.619  19.299 43.424 1.000 31.723  0 181  PHE A CZ  1 ? 
ATOM   1381 N N   . SER A 1 182 ? 6.125  25.767 42.768 1.000 21.005  0 182  SER A N   1 ? 
ATOM   1382 C CA  . SER A 1 182 ? 6.013  27.218 42.802 1.000 21.659  0 182  SER A CA  1 ? 
ATOM   1383 C C   . SER A 1 182 ? 7.031  27.841 43.763 1.000 21.588  0 182  SER A C   1 ? 
ATOM   1384 O O   . SER A 1 182 ? 7.314  29.026 43.677 1.000 24.898  0 182  SER A O   1 ? 
ATOM   1385 C CB  . SER A 1 182 ? 4.632  27.611 43.125 1.000 21.727  0 182  SER A CB  1 ? 
ATOM   1386 O OG  . SER A 1 182 ? 4.266  27.289 44.464 1.000 23.372  0 182  SER A OG  1 ? 
ATOM   1387 N N   . TYR A 1 183 ? 7.541  27.069 44.709 1.000 20.569  0 183  TYR A N   1 ? 
ATOM   1388 C CA  . TYR A 1 183 ? 8.572  27.515 45.616 1.000 23.216  0 183  TYR A CA  1 ? 
ATOM   1389 C C   . TYR A 1 183 ? 9.267  26.264 46.110 1.000 25.147  0 183  TYR A C   1 ? 
ATOM   1390 O O   . TYR A 1 183 ? 8.819  25.158 45.850 1.000 26.049  0 183  TYR A O   1 ? 
ATOM   1391 C CB  . TYR A 1 183 ? 8.002  28.425 46.707 1.000 24.366  0 183  TYR A CB  1 ? 
ATOM   1392 C CG  . TYR A 1 183 ? 7.207  27.724 47.769 1.000 23.332  0 183  TYR A CG  1 ? 
ATOM   1393 C CD1 . TYR A 1 183 ? 5.918  27.266 47.565 1.000 22.890  0 183  TYR A CD1 1 ? 
ATOM   1394 C CD2 . TYR A 1 183 ? 7.750  27.544 49.033 1.000 24.520  0 183  TYR A CD2 1 ? 
ATOM   1395 C CE1 . TYR A 1 183 ? 5.201  26.605 48.552 1.000 23.664  0 183  TYR A CE1 1 ? 
ATOM   1396 C CE2 . TYR A 1 183 ? 7.020  26.946 50.054 1.000 25.335  0 183  TYR A CE2 1 ? 
ATOM   1397 C CZ  . TYR A 1 183 ? 5.755  26.456 49.806 1.000 27.991  0 183  TYR A CZ  1 ? 
ATOM   1398 O OH  . TYR A 1 183 ? 5.034  25.810 50.773 1.000 29.702  0 183  TYR A OH  1 ? 
ATOM   1399 N N   . VAL A 1 184 ? 10.368 26.464 46.815 1.000 27.795  0 184  VAL A N   1 ? 
ATOM   1400 C CA  . VAL A 1 184 ? 11.279 25.370 47.091 1.000 27.833  0 184  VAL A CA  1 ? 
ATOM   1401 C C   . VAL A 1 184 ? 10.567 24.296 47.903 1.000 28.690  0 184  VAL A C   1 ? 
ATOM   1402 O O   . VAL A 1 184 ? 10.705 23.128 47.548 1.000 33.594  0 184  VAL A O   1 ? 
ATOM   1403 C CB  . VAL A 1 184 ? 12.556 25.868 47.792 1.000 32.522  0 184  VAL A CB  1 ? 
ATOM   1404 C CG1 . VAL A 1 184 ? 13.345 24.715 48.359 1.000 34.102  0 184  VAL A CG1 1 ? 
ATOM   1405 C CG2 . VAL A 1 184 ? 13.416 26.697 46.886 1.000 35.238  0 184  VAL A CG2 1 ? 
ATOM   1406 N N   . LEU A 1 185 ? 9.709  24.629 48.877 1.000 27.865  0 185  LEU A N   1 ? 
ATOM   1407 C CA  . LEU A 1 185 ? 9.106  23.630 49.739 1.000 30.813  0 185  LEU A CA  1 ? 
ATOM   1408 C C   . LEU A 1 185 ? 7.669  23.361 49.386 1.000 31.115  0 185  LEU A C   1 ? 
ATOM   1409 O O   . LEU A 1 185 ? 6.907  22.921 50.229 1.000 31.127  0 185  LEU A O   1 ? 
ATOM   1410 C CB  . LEU A 1 185 ? 9.143  24.101 51.191 1.000 35.592  0 185  LEU A CB  1 ? 
ATOM   1411 C CG  . LEU A 1 185 ? 10.505 24.130 51.859 1.000 41.443  0 185  LEU A CG  1 ? 
ATOM   1412 C CD1 . LEU A 1 185 ? 10.309 24.484 53.328 1.000 36.900  0 185  LEU A CD1 1 ? 
ATOM   1413 C CD2 . LEU A 1 185 ? 11.241 22.814 51.704 1.000 46.367  0 185  LEU A CD2 1 ? 
ATOM   1414 N N   . ASP A 1 186 ? 7.273  23.689 48.151 1.000 25.637  0 186  ASP A N   1 ? 
ATOM   1415 C CA  . ASP A 1 186 ? 5.969  23.332 47.665 1.000 26.240  0 186  ASP A CA  1 ? 
ATOM   1416 C C   . ASP A 1 186 ? 5.741  21.828 47.812 1.000 29.220  0 186  ASP A C   1 ? 
ATOM   1417 O O   . ASP A 1 186 ? 6.702  21.069 47.764 1.000 33.662  0 186  ASP A O   1 ? 
ATOM   1418 C CB  . ASP A 1 186 ? 5.900  23.764 46.213 1.000 26.444  0 186  ASP A CB  1 ? 
ATOM   1419 C CG  . ASP A 1 186 ? 4.512  24.062 45.705 1.000 28.074  0 186  ASP A CG  1 ? 
ATOM   1420 O OD1 . ASP A 1 186 ? 3.533  23.880 46.437 1.000 28.306  0 186  ASP A OD1 1 ? 
ATOM   1421 O OD2 . ASP A 1 186 ? 4.416  24.529 44.587 1.000 27.591  0 186  ASP A OD2 1 ? 
ATOM   1422 N N   . LYS A 1 187 ? 4.491  21.471 48.061 1.000 33.157  0 187  LYS A N   1 ? 
ATOM   1423 C CA  . LYS A 1 187 ? 4.074  20.086 48.069 1.000 38.096  0 187  LYS A CA  1 ? 
ATOM   1424 C C   . LYS A 1 187 ? 4.460  19.529 46.698 1.000 34.251  0 187  LYS A C   1 ? 
ATOM   1425 O O   . LYS A 1 187 ? 4.128  20.132 45.674 1.000 32.657  0 187  LYS A O   1 ? 
ATOM   1426 C CB  . LYS A 1 187 ? 2.571  19.986 48.355 1.000 45.792  0 187  LYS A CB  1 ? 
ATOM   1427 C CG  . LYS A 1 187 ? 1.942  18.606 48.152 1.000 60.283  0 187  LYS A CG  1 ? 
ATOM   1428 C CD  . LYS A 1 187 ? 0.607  18.731 47.389 1.000 81.732  0 187  LYS A CD  1 ? 
ATOM   1429 C CE  . LYS A 1 187 ? 0.126  17.473 46.690 1.000 88.005  0 187  LYS A CE  1 ? 
ATOM   1430 N NZ  . LYS A 1 187 ? -1.018 16.866 47.417 1.000 92.437  0 187  LYS A NZ  1 ? 
ATOM   1431 N N   . PRO A 1 188 ? 5.231  18.435 46.666 1.000 37.511  0 188  PRO A N   1 ? 
ATOM   1432 C CA  . PRO A 1 188 ? 5.866  17.987 45.426 1.000 40.103  0 188  PRO A CA  1 ? 
ATOM   1433 C C   . PRO A 1 188 ? 4.850  17.600 44.366 1.000 36.200  0 188  PRO A C   1 ? 
ATOM   1434 O O   . PRO A 1 188 ? 3.783  17.065 44.637 1.000 33.784  0 188  PRO A O   1 ? 
ATOM   1435 C CB  . PRO A 1 188 ? 6.782  16.827 45.863 1.000 41.808  0 188  PRO A CB  1 ? 
ATOM   1436 C CG  . PRO A 1 188 ? 6.981  17.058 47.349 1.000 50.455  0 188  PRO A CG  1 ? 
ATOM   1437 C CD  . PRO A 1 188 ? 5.663  17.643 47.832 1.000 45.363  0 188  PRO A CD  1 ? 
ATOM   1438 N N   . THR A 1 189 ? 5.131  18.042 43.138 1.000 32.159  0 189  THR A N   1 ? 
ATOM   1439 C CA  . THR A 1 189 ? 4.306  17.679 42.003 1.000 32.811  0 189  THR A CA  1 ? 
ATOM   1440 C C   . THR A 1 189 ? 5.102  16.733 41.114 1.000 29.856  0 189  THR A C   1 ? 
ATOM   1441 O O   . THR A 1 189 ? 4.772  16.561 39.952 1.000 31.810  0 189  THR A O   1 ? 
ATOM   1442 C CB  . THR A 1 189 ? 3.912  18.951 41.269 1.000 32.956  0 189  THR A CB  1 ? 
ATOM   1443 O OG1 . THR A 1 189 ? 5.106  19.707 41.058 1.000 35.607  0 189  THR A OG1 1 ? 
ATOM   1444 C CG2 . THR A 1 189 ? 2.912  19.727 42.097 1.000 38.200  0 189  THR A CG2 1 ? 
ATOM   1445 N N   . THR A 1 190 ? 6.127  16.125 41.708 1.000 33.797  0 190  THR A N   1 ? 
ATOM   1446 C CA  . THR A 1 190 ? 6.936  15.141 41.023 1.000 29.322  0 190  THR A CA  1 ? 
ATOM   1447 C C   . THR A 1 190 ? 6.047  13.987 40.599 1.000 35.855  0 190  THR A C   1 ? 
ATOM   1448 O O   . THR A 1 190 ? 5.196  13.544 41.365 1.000 34.983  0 190  THR A O   1 ? 
ATOM   1449 C CB  . THR A 1 190 ? 8.063  14.715 41.958 1.000 33.561  0 190  THR A CB  1 ? 
ATOM   1450 O OG1 . THR A 1 190 ? 8.651  15.959 42.329 1.000 37.153  0 190  THR A OG1 1 ? 
ATOM   1451 C CG2 . THR A 1 190 ? 9.084  13.837 41.274 1.000 32.868  0 190  THR A CG2 1 ? 
ATOM   1452 N N   . VAL A 1 191 ? 6.270  13.516 39.383 1.000 28.835  0 191  VAL A N   1 ? 
ATOM   1453 C CA  . VAL A 1 191 ? 5.664  12.305 38.862 1.000 30.889  0 191  VAL A CA  1 ? 
ATOM   1454 C C   . VAL A 1 191 ? 6.709  11.209 38.835 1.000 27.633  0 191  VAL A C   1 ? 
ATOM   1455 O O   . VAL A 1 191 ? 7.841  11.421 38.401 1.000 28.612  0 191  VAL A O   1 ? 
ATOM   1456 C CB  . VAL A 1 191 ? 5.125  12.535 37.450 1.000 30.643  0 191  VAL A CB  1 ? 
ATOM   1457 C CG1 . VAL A 1 191 ? 4.651  11.235 36.822 1.000 33.987  0 191  VAL A CG1 1 ? 
ATOM   1458 C CG2 . VAL A 1 191 ? 4.042  13.594 37.478 1.000 32.274  0 191  VAL A CG2 1 ? 
ATOM   1459 N N   . THR A 1 192 ? 6.279  10.017 39.276 1.000 29.611  0 192  THR A N   1 ? 
ATOM   1460 C CA  . THR A 1 192 ? 7.155  8.869  39.291 1.000 29.976  0 192  THR A CA  1 ? 
ATOM   1461 C C   . THR A 1 192 ? 6.797  8.052  38.071 1.000 28.757  0 192  THR A C   1 ? 
ATOM   1462 O O   . THR A 1 192 ? 5.632  7.744  37.859 1.000 31.512  0 192  THR A O   1 ? 
ATOM   1463 C CB  . THR A 1 192 ? 6.955  8.018  40.554 1.000 35.662  0 192  THR A CB  1 ? 
ATOM   1464 O OG1 . THR A 1 192 ? 7.197  8.841  41.683 1.000 34.051  0 192  THR A OG1 1 ? 
ATOM   1465 C CG2 . THR A 1 192 ? 7.910  6.847  40.616 1.000 40.047  0 192  THR A CG2 1 ? 
ATOM   1466 N N   . CYS A 1 193 ? 7.795  7.790  37.269 1.000 29.446  0 193  CYS A N   1 ? 
ATOM   1467 C CA  . CYS A 1 193 ? 7.652  6.979  36.091 1.000 31.217  0 193  CYS A CA  1 ? 
ATOM   1468 C C   . CYS A 1 193 ? 8.543  5.759  36.214 1.000 29.151  0 193  CYS A C   1 ? 
ATOM   1469 O O   . CYS A 1 193 ? 9.546  5.763  36.914 1.000 29.672  0 193  CYS A O   1 ? 
ATOM   1470 C CB  . CYS A 1 193 ? 8.129  7.709  34.851 1.000 31.619  0 193  CYS A CB  1 ? 
ATOM   1471 S SG  . CYS A 1 193 ? 7.024  9.071  34.422 1.000 31.839  0 193  CYS A SG  1 ? 
ATOM   1472 N N   . PRO A 1 194 ? 8.249  4.720  35.421 1.000 32.960  0 194  PRO A N   1 ? 
ATOM   1473 C CA  . PRO A 1 194 ? 9.152  3.581  35.353 1.000 33.604  0 194  PRO A CA  1 ? 
ATOM   1474 C C   . PRO A 1 194 ? 10.542 4.027  34.968 1.000 32.730  0 194  PRO A C   1 ? 
ATOM   1475 O O   . PRO A 1 194 ? 10.705 4.881  34.095 1.000 35.262  0 194  PRO A O   1 ? 
ATOM   1476 C CB  . PRO A 1 194 ? 8.532  2.742  34.231 1.000 38.244  0 194  PRO A CB  1 ? 
ATOM   1477 C CG  . PRO A 1 194 ? 7.063  3.081  34.286 1.000 35.581  0 194  PRO A CG  1 ? 
ATOM   1478 C CD  . PRO A 1 194 ? 7.020  4.563  34.626 1.000 38.574  0 194  PRO A CD  1 ? 
ATOM   1479 N N   . GLY A 1 195 ? 11.555 3.395  35.563 1.000 30.531  0 195  GLY A N   1 ? 
ATOM   1480 C CA  . GLY A 1 195 ? 12.934 3.623  35.181 1.000 29.202  0 195  GLY A CA  1 ? 
ATOM   1481 C C   . GLY A 1 195 ? 13.072 3.432  33.687 1.000 32.301  0 195  GLY A C   1 ? 
ATOM   1482 O O   . GLY A 1 195 ? 12.421 2.539  33.150 1.000 33.478  0 195  GLY A O   1 ? 
ATOM   1483 N N   . SER A 1 196 ? 13.898 4.260  33.050 1.000 28.807  0 196  SER A N   1 ? 
ATOM   1484 C CA  . SER A 1 196 ? 14.186 4.140  31.621 1.000 32.142  0 196  SER A CA  1 ? 
ATOM   1485 C C   . SER A 1 196 ? 12.980 4.448  30.740 1.000 34.554  0 196  SER A C   1 ? 
ATOM   1486 O O   . SER A 1 196 ? 12.875 3.930  29.634 1.000 34.187  0 196  SER A O   1 ? 
ATOM   1487 C CB  . SER A 1 196 ? 14.713 2.742  31.314 1.000 34.472  0 196  SER A CB  1 ? 
ATOM   1488 O OG  . SER A 1 196 ? 15.996 2.651  31.873 1.000 38.173  0 196  SER A OG  1 ? 
ATOM   1489 N N   . SER A 1 197 ? 12.093 5.316  31.195 1.000 29.905  0 197  SER A N   1 ? 
ATOM   1490 C CA  . SER A 1 197 ? 11.049 5.856  30.339 1.000 28.933  0 197  SER A CA  1 ? 
ATOM   1491 C C   . SER A 1 197 ? 11.680 6.797  29.324 1.000 24.991  0 197  SER A C   1 ? 
ATOM   1492 O O   . SER A 1 197 ? 12.819 7.191  29.460 1.000 29.883  0 197  SER A O   1 ? 
ATOM   1493 C CB  . SER A 1 197 ? 9.967  6.539  31.147 1.000 30.348  0 197  SER A CB  1 ? 
ATOM   1494 O OG  . SER A 1 197 ? 9.354  5.626  32.052 1.000 30.879  0 197  SER A OG  1 ? 
ATOM   1495 N N   . ASN A 1 198 ? 10.912 7.105  28.277 1.000 27.370  0 198  ASN A N   1 ? 
ATOM   1496 C CA  . ASN A 1 198 ? 11.270 8.120  27.307 1.000 27.090  0 198  ASN A CA  1 ? 
ATOM   1497 C C   . ASN A 1 198 ? 10.235 9.228  27.397 1.000 23.353  0 198  ASN A C   1 ? 
ATOM   1498 O O   . ASN A 1 198 ? 9.164  9.072  27.938 1.000 25.198  0 198  ASN A O   1 ? 
ATOM   1499 C CB  . ASN A 1 198 ? 11.341 7.580  25.895 1.000 27.297  0 198  ASN A CB  1 ? 
ATOM   1500 C CG  . ASN A 1 198 ? 12.450 6.559  25.729 1.000 31.185  0 198  ASN A CG  1 ? 
ATOM   1501 O OD1 . ASN A 1 198 ? 13.540 6.683  26.256 1.000 29.310  0 198  ASN A OD1 1 ? 
ATOM   1502 N ND2 . ASN A 1 198 ? 12.140 5.478  25.043 1.000 38.525  0 198  ASN A ND2 1 ? 
ATOM   1503 N N   . TYR A 1 199 ? 10.616 10.396 26.881 1.000 24.812  0 199  TYR A N   1 ? 
ATOM   1504 C CA  . TYR A 1 199 ? 9.825  11.570 27.166 1.000 22.513  0 199  TYR A CA  1 ? 
ATOM   1505 C C   . TYR A 1 199 ? 9.792  12.524 25.982 1.000 22.366  0 199  TYR A C   1 ? 
ATOM   1506 O O   . TYR A 1 199 ? 10.660 12.467 25.106 1.000 24.393  0 199  TYR A O   1 ? 
ATOM   1507 C CB  . TYR A 1 199 ? 10.470 12.345 28.330 1.000 22.688  0 199  TYR A CB  1 ? 
ATOM   1508 C CG  . TYR A 1 199 ? 10.565 11.550 29.602 1.000 22.422  0 199  TYR A CG  1 ? 
ATOM   1509 C CD1 . TYR A 1 199 ? 9.459  11.427 30.410 1.000 23.648  0 199  TYR A CD1 1 ? 
ATOM   1510 C CD2 . TYR A 1 199 ? 11.714 10.847 29.907 1.000 25.087  0 199  TYR A CD2 1 ? 
ATOM   1511 C CE1 . TYR A 1 199 ? 9.502  10.651 31.558 1.000 25.566  0 199  TYR A CE1 1 ? 
ATOM   1512 C CE2 . TYR A 1 199 ? 11.775 10.080 31.059 1.000 23.659  0 199  TYR A CE2 1 ? 
ATOM   1513 C CZ  . TYR A 1 199 ? 10.643 9.925  31.831 1.000 24.713  0 199  TYR A CZ  1 ? 
ATOM   1514 O OH  . TYR A 1 199 ? 10.657 9.183  33.020 1.000 28.410  0 199  TYR A OH  1 ? 
ATOM   1515 N N   . ARG A 1 200 ? 8.773  13.371 26.022 1.000 23.560  0 200  ARG A N   1 ? 
ATOM   1516 C CA  . ARG A 1 200 ? 8.658  14.484 25.100 1.000 22.814  0 200  ARG A CA  1 ? 
ATOM   1517 C C   . ARG A 1 200 ? 8.425  15.770 25.887 1.000 22.507  0 200  ARG A C   1 ? 
ATOM   1518 O O   . ARG A 1 200 ? 7.599  15.784 26.771 1.000 24.247  0 200  ARG A O   1 ? 
ATOM   1519 C CB  . ARG A 1 200 ? 7.485  14.285 24.143 1.000 23.377  0 200  ARG A CB  1 ? 
ATOM   1520 C CG  . ARG A 1 200 ? 7.358  15.415 23.150 1.000 26.256  0 200  ARG A CG  1 ? 
ATOM   1521 C CD  . ARG A 1 200 ? 6.228  15.169 22.193 1.000 30.535  0 200  ARG A CD  1 ? 
ATOM   1522 N NE  . ARG A 1 200 ? 6.674  14.113 21.300 1.000 30.251  0 200  ARG A NE  1 ? 
ATOM   1523 C CZ  . ARG A 1 200 ? 6.015  12.999 21.106 1.000 37.670  0 200  ARG A CZ  1 ? 
ATOM   1524 N NH1 . ARG A 1 200 ? 4.972  12.730 21.861 1.000 39.732  0 200  ARG A NH1 1 ? 
ATOM   1525 N NH2 . ARG A 1 200 ? 6.425  12.146 20.182 1.000 37.650  0 200  ARG A NH2 1 ? 
ATOM   1526 N N   . VAL A 1 201 ? 9.257  16.765 25.595 1.000 21.612  0 201  VAL A N   1 ? 
ATOM   1527 C CA  . VAL A 1 201 ? 9.026  18.092 26.120 1.000 19.908  0 201  VAL A CA  1 ? 
ATOM   1528 C C   . VAL A 1 201 ? 8.499  18.913 24.969 1.000 19.549  0 201  VAL A C   1 ? 
ATOM   1529 O O   . VAL A 1 201 ? 9.166  19.037 23.962 1.000 21.568  0 201  VAL A O   1 ? 
ATOM   1530 C CB  . VAL A 1 201 ? 10.310 18.702 26.670 1.000 22.472  0 201  VAL A CB  1 ? 
ATOM   1531 C CG1 . VAL A 1 201 ? 10.027 20.103 27.158 1.000 26.477  0 201  VAL A CG1 1 ? 
ATOM   1532 C CG2 . VAL A 1 201 ? 10.912 17.854 27.761 1.000 25.268  0 201  VAL A CG2 1 ? 
ATOM   1533 N N   . THR A 1 202 ? 7.339  19.498 25.163 1.000 21.122  0 202  THR A N   1 ? 
ATOM   1534 C CA  . THR A 1 202 ? 6.739  20.313 24.141 1.000 20.775  0 202  THR A CA  1 ? 
ATOM   1535 C C   . THR A 1 202 ? 6.643  21.739 24.679 1.000 20.760  0 202  THR A C   1 ? 
ATOM   1536 O O   . THR A 1 202 ? 5.927  21.986 25.646 1.000 23.695  0 202  THR A O   1 ? 
ATOM   1537 C CB  . THR A 1 202 ? 5.358  19.807 23.739 1.000 22.698  0 202  THR A CB  1 ? 
ATOM   1538 O OG1 . THR A 1 202 ? 5.419  18.428 23.418 1.000 23.572  0 202  THR A OG1 1 ? 
ATOM   1539 C CG2 . THR A 1 202 ? 4.732  20.572 22.602 1.000 23.819  0 202  THR A CG2 1 ? 
ATOM   1540 N N   . PHE A 1 203 ? 7.235  22.637 23.940 1.000 20.991  0 203  PHE A N   1 ? 
ATOM   1541 C CA  . PHE A 1 203 ? 7.072  24.040 24.229 1.000 19.591  0 203  PHE A CA  1 ? 
ATOM   1542 C C   . PHE A 1 203 ? 5.828  24.538 23.520 1.000 19.916  0 203  PHE A C   1 ? 
ATOM   1543 O O   . PHE A 1 203 ? 5.583  24.131 22.397 1.000 21.308  0 203  PHE A O   1 ? 
ATOM   1544 C CB  . PHE A 1 203 ? 8.275  24.815 23.773 1.000 19.971  0 203  PHE A CB  1 ? 
ATOM   1545 C CG  . PHE A 1 203 ? 9.568  24.321 24.344 1.000 21.535  0 203  PHE A CG  1 ? 
ATOM   1546 C CD1 . PHE A 1 203 ? 9.794  24.339 25.697 1.000 24.569  0 203  PHE A CD1 1 ? 
ATOM   1547 C CD2 . PHE A 1 203 ? 10.571 23.935 23.500 1.000 23.641  0 203  PHE A CD2 1 ? 
ATOM   1548 C CE1 . PHE A 1 203 ? 10.991 23.890 26.188 1.000 25.781  0 203  PHE A CE1 1 ? 
ATOM   1549 C CE2 . PHE A 1 203 ? 11.793 23.566 24.008 1.000 25.679  0 203  PHE A CE2 1 ? 
ATOM   1550 C CZ  . PHE A 1 203 ? 11.977 23.489 25.340 1.000 24.607  0 203  PHE A CZ  1 ? 
ATOM   1551 N N   . CYS A 1 204 ? 5.056  25.382 24.220 1.000 20.521  0 204  CYS A N   1 ? 
ATOM   1552 C CA  . CYS A 1 204 ? 3.784  25.903 23.753 1.000 20.802  0 204  CYS A CA  1 ? 
ATOM   1553 C C   . CYS A 1 204 ? 2.850  24.781 23.320 1.000 22.127  0 204  CYS A C   1 ? 
ATOM   1554 O O   . CYS A 1 204 ? 2.413  24.695 22.164 1.000 22.966  0 204  CYS A O   1 ? 
ATOM   1555 C CB  . CYS A 1 204 ? 3.927  26.887 22.610 1.000 22.582  0 204  CYS A CB  1 ? 
ATOM   1556 S SG  . CYS A 1 204 ? 4.989  28.281 23.009 1.000 24.150  0 204  CYS A SG  1 ? 
ATOM   1557 N N   . PRO A 1 205 ? 2.500  23.901 24.255 1.000 22.124  0 205  PRO A N   1 ? 
ATOM   1558 C CA  . PRO A 1 205 ? 1.716  22.733 23.914 1.000 24.463  0 205  PRO A CA  1 ? 
ATOM   1559 C C   . PRO A 1 205 ? 0.323  23.059 23.413 1.000 27.559  0 205  PRO A C   1 ? 
ATOM   1560 O O   . PRO A 1 205 ? -0.221 22.241 22.720 1.000 28.232  0 205  PRO A O   1 ? 
ATOM   1561 C CB  . PRO A 1 205 ? 1.707  21.929 25.218 1.000 28.148  0 205  PRO A CB  1 ? 
ATOM   1562 C CG  . PRO A 1 205 ? 1.880  22.943 26.270 1.000 26.497  0 205  PRO A CG  1 ? 
ATOM   1563 C CD  . PRO A 1 205 ? 2.866  23.924 25.688 1.000 25.497  0 205  PRO A CD  1 ? 
ATOM   1564 N N   . THR A 1 206 ? -0.272 24.203 23.729 1.000 29.410  0 206  THR A N   1 ? 
ATOM   1565 C CA  . THR A 1 206 ? -1.692 24.343 23.375 1.000 41.138  0 206  THR A CA  1 ? 
ATOM   1566 C C   . THR A 1 206 ? -1.970 25.291 22.193 1.000 45.131  0 206  THR A C   1 ? 
ATOM   1567 O O   . THR A 1 206 ? -1.003 25.797 21.643 1.000 52.099  0 206  THR A O   1 ? 
ATOM   1568 C CB  . THR A 1 206 ? -2.485 24.747 24.623 1.000 44.899  0 206  THR A CB  1 ? 
ATOM   1569 O OG1 . THR A 1 206 ? -1.919 25.992 24.999 1.000 49.199  0 206  THR A OG1 1 ? 
ATOM   1570 C CG2 . THR A 1 206 ? -2.378 23.748 25.756 1.000 45.002  0 206  THR A CG2 1 ? 
HETATM 1571 O O1  . TLA B 2 .   ? 12.170 19.978 11.343 1.000 25.302  0 1001 TLA A O1  1 ? 
HETATM 1572 O O11 . TLA B 2 .   ? 11.657 18.552 12.980 1.000 25.177  0 1001 TLA A O11 1 ? 
HETATM 1573 C C1  . TLA B 2 .   ? 12.385 19.002 12.078 1.000 22.339  0 1001 TLA A C1  1 ? 
HETATM 1574 C C2  . TLA B 2 .   ? 13.738 18.330 11.956 1.000 25.058  0 1001 TLA A C2  1 ? 
HETATM 1575 O O2  . TLA B 2 .   ? 13.672 17.146 12.723 1.000 25.952  0 1001 TLA A O2  1 ? 
HETATM 1576 C C3  . TLA B 2 .   ? 14.803 19.292 12.475 1.000 28.494  0 1001 TLA A C3  1 ? 
HETATM 1577 O O3  . TLA B 2 .   ? 14.529 19.610 13.838 1.000 27.094  0 1001 TLA A O3  1 ? 
HETATM 1578 C C4  . TLA B 2 .   ? 16.173 18.624 12.317 1.000 33.081  0 1001 TLA A C4  1 ? 
HETATM 1579 O O4  . TLA B 2 .   ? 16.597 18.464 11.166 1.000 32.280  0 1001 TLA A O4  1 ? 
HETATM 1580 O O41 . TLA B 2 .   ? 16.658 18.155 13.334 1.000 31.186  0 1001 TLA A O41 1 ? 
HETATM 1581 O O   . HOH C 3 .   ? 16.604 32.528 41.626 1.000 51.028  0 1101 HOH A O   1 ? 
HETATM 1582 O O   . HOH C 3 .   ? 13.277 36.640 54.544 1.000 25.861  0 1102 HOH A O   1 ? 
HETATM 1583 O O   . HOH C 3 .   ? 19.183 30.866 49.550 1.000 49.207  0 1103 HOH A O   1 ? 
HETATM 1584 O O   . HOH C 3 .   ? 22.740 38.913 45.421 1.000 26.514  0 1104 HOH A O   1 ? 
HETATM 1585 O O   . HOH C 3 .   ? -0.210 19.046 34.577 1.000 38.402  0 1105 HOH A O   1 ? 
HETATM 1586 O O   . HOH C 3 .   ? 24.398 8.641  34.283 1.000 50.285  0 1106 HOH A O   1 ? 
HETATM 1587 O O   . HOH C 3 .   ? 12.367 36.902 25.221 1.000 38.804  0 1107 HOH A O   1 ? 
HETATM 1588 O O   . HOH C 3 .   ? 22.304 8.953  39.472 1.000 58.045  0 1108 HOH A O   1 ? 
HETATM 1589 O O   . HOH C 3 .   ? 1.505  24.912 47.505 1.000 48.241  0 1109 HOH A O   1 ? 
HETATM 1590 O O   . HOH C 3 .   ? 1.809  20.963 44.998 1.000 36.462  0 1110 HOH A O   1 ? 
HETATM 1591 O O   . HOH C 3 .   ? 13.401 5.720  43.636 1.000 47.286  0 1111 HOH A O   1 ? 
HETATM 1592 O O   . HOH C 3 .   ? 7.821  4.119  30.657 1.000 42.072  0 1112 HOH A O   1 ? 
HETATM 1593 O O   . HOH C 3 .   ? 14.605 7.350  31.558 1.000 30.889  0 1113 HOH A O   1 ? 
HETATM 1594 O O   . HOH C 3 .   ? 6.064  25.490 53.117 1.000 40.442  0 1114 HOH A O   1 ? 
HETATM 1595 O O   . HOH C 3 .   ? 4.305  31.799 24.545 1.000 38.846  0 1115 HOH A O   1 ? 
HETATM 1596 O O   . HOH C 3 .   ? 21.824 34.648 44.539 1.000 53.292  0 1116 HOH A O   1 ? 
HETATM 1597 O O   . HOH C 3 .   ? 9.306  23.862 11.093 1.000 27.460  0 1117 HOH A O   1 ? 
HETATM 1598 O O   . HOH C 3 .   ? 0.530  16.670 30.330 1.000 44.897  0 1118 HOH A O   1 ? 
HETATM 1599 O O   . HOH C 3 .   ? 9.108  18.329 13.986 1.000 23.740  0 1119 HOH A O   1 ? 
HETATM 1600 O O   . HOH C 3 .   ? 5.130  16.803 25.685 1.000 25.738  0 1120 HOH A O   1 ? 
HETATM 1601 O O   . HOH C 3 .   ? 21.534 16.358 19.275 1.000 49.013  0 1121 HOH A O   1 ? 
HETATM 1602 O O   . HOH C 3 .   ? 1.168  26.472 20.351 1.000 45.624  0 1122 HOH A O   1 ? 
HETATM 1603 O O   . HOH C 3 .   ? 12.648 33.593 20.630 1.000 26.003  0 1123 HOH A O   1 ? 
HETATM 1604 O O   . HOH C 3 .   ? 13.352 24.001 40.283 1.000 33.782  0 1124 HOH A O   1 ? 
HETATM 1605 O O   . HOH C 3 .   ? 14.666 5.595  21.648 1.000 55.415  0 1125 HOH A O   1 ? 
HETATM 1606 O O   . HOH C 3 .   ? 8.566  12.212 16.257 1.000 28.516  0 1126 HOH A O   1 ? 
HETATM 1607 O O   . HOH C 3 .   ? 14.234 30.383 54.449 1.000 37.350  0 1127 HOH A O   1 ? 
HETATM 1608 O O   . HOH C 3 .   ? 13.572 21.575 9.764  1.000 24.551  0 1128 HOH A O   1 ? 
HETATM 1609 O O   . HOH C 3 .   ? 23.474 12.116 29.173 1.000 50.360  0 1129 HOH A O   1 ? 
HETATM 1610 O O   . HOH C 3 .   ? 28.444 35.563 24.735 1.000 40.138  0 1130 HOH A O   1 ? 
HETATM 1611 O O   . HOH C 3 .   ? 16.681 28.964 46.518 1.000 44.152  0 1131 HOH A O   1 ? 
HETATM 1612 O O   . HOH C 3 .   ? -2.284 35.079 46.941 1.000 51.086  0 1132 HOH A O   1 ? 
HETATM 1613 O O   . HOH C 3 .   ? 23.610 21.989 18.665 1.000 38.841  0 1133 HOH A O   1 ? 
HETATM 1614 O O   . HOH C 3 .   ? 2.848  33.218 28.924 1.000 31.854  0 1134 HOH A O   1 ? 
HETATM 1615 O O   . HOH C 3 .   ? 8.261  30.708 41.838 1.000 28.945  0 1135 HOH A O   1 ? 
HETATM 1616 O O   . HOH C 3 .   ? 16.768 25.052 13.433 1.000 36.555  0 1136 HOH A O   1 ? 
HETATM 1617 O O   . HOH C 3 .   ? 5.532  18.809 38.146 1.000 28.110  0 1137 HOH A O   1 ? 
HETATM 1618 O O   . HOH C 3 .   ? 9.349  20.653 47.879 1.000 40.633  0 1138 HOH A O   1 ? 
HETATM 1619 O O   . HOH C 3 .   ? 27.114 15.800 26.083 1.000 48.233  0 1139 HOH A O   1 ? 
HETATM 1620 O O   . HOH C 3 .   ? 17.213 28.044 35.103 1.000 32.914  0 1140 HOH A O   1 ? 
HETATM 1621 O O   . HOH C 3 .   ? 17.593 5.060  29.306 1.000 48.290  0 1141 HOH A O   1 ? 
HETATM 1622 O O   . HOH C 3 .   ? 17.171 6.293  31.441 1.000 28.480  0 1142 HOH A O   1 ? 
HETATM 1623 O O   . HOH C 3 .   ? 16.615 36.152 18.099 1.000 40.377  0 1143 HOH A O   1 ? 
HETATM 1624 O O   . HOH C 3 .   ? 14.635 4.649  27.675 1.000 44.851  0 1144 HOH A O   1 ? 
HETATM 1625 O O   . HOH C 3 .   ? 0.766  41.363 33.828 1.000 44.832  0 1145 HOH A O   1 ? 
HETATM 1626 O O   . HOH C 3 .   ? 11.784 27.033 29.379 1.000 21.545  0 1146 HOH A O   1 ? 
HETATM 1627 O O   . HOH C 3 .   ? -1.274 29.267 51.840 1.000 57.975  0 1147 HOH A O   1 ? 
HETATM 1628 O O   . HOH C 3 .   ? 7.952  32.338 47.358 1.000 23.147  0 1148 HOH A O   1 ? 
HETATM 1629 O O   . HOH C 3 .   ? 21.782 40.647 43.495 1.000 29.272  0 1149 HOH A O   1 ? 
HETATM 1630 O O   . HOH C 3 .   ? 10.833 44.358 40.627 1.000 41.490  0 1150 HOH A O   1 ? 
HETATM 1631 O O   . HOH C 3 .   ? -4.395 28.156 34.735 1.000 51.136  0 1151 HOH A O   1 ? 
HETATM 1632 O O   . HOH C 3 .   ? 12.585 33.940 56.168 1.000 30.073  0 1152 HOH A O   1 ? 
HETATM 1633 O O   . HOH C 3 .   ? 11.529 27.469 36.991 1.000 21.836  0 1153 HOH A O   1 ? 
HETATM 1634 O O   . HOH C 3 .   ? -0.138 23.137 35.964 1.000 28.313  0 1154 HOH A O   1 ? 
HETATM 1635 O O   . HOH C 3 .   ? 4.502  14.126 43.954 1.000 48.934  0 1155 HOH A O   1 ? 
HETATM 1636 O O   . HOH C 3 .   ? 14.778 30.882 42.527 1.000 36.149  0 1156 HOH A O   1 ? 
HETATM 1637 O O   . HOH C 3 .   ? 23.325 17.019 38.111 1.000 48.651  0 1157 HOH A O   1 ? 
HETATM 1638 O O   . HOH C 3 .   ? 3.813  42.962 44.305 1.000 45.385  0 1158 HOH A O   1 ? 
HETATM 1639 O O   . HOH C 3 .   ? 30.344 30.648 29.266 1.000 56.702  0 1159 HOH A O   1 ? 
HETATM 1640 O O   . HOH C 3 .   ? 18.730 33.585 43.181 1.000 50.513  0 1160 HOH A O   1 ? 
HETATM 1641 O O   . HOH C 3 .   ? 5.493  31.621 12.984 1.000 48.082  0 1161 HOH A O   1 ? 
HETATM 1642 O O   . HOH C 3 .   ? 21.194 4.565  38.280 1.000 48.501  0 1162 HOH A O   1 ? 
HETATM 1643 O O   . HOH C 3 .   ? 3.810  9.664  40.478 1.000 47.979  0 1163 HOH A O   1 ? 
HETATM 1644 O O   . HOH C 3 .   ? -1.060 35.638 44.671 1.000 29.779  0 1164 HOH A O   1 ? 
HETATM 1645 O O   . HOH C 3 .   ? 8.195  45.027 46.815 1.000 35.742  0 1165 HOH A O   1 ? 
HETATM 1646 O O   . HOH C 3 .   ? 14.520 38.307 30.722 1.000 40.803  0 1166 HOH A O   1 ? 
HETATM 1647 O O   . HOH C 3 .   ? -1.273 24.202 32.343 1.000 38.016  0 1167 HOH A O   1 ? 
HETATM 1648 O O   . HOH C 3 .   ? -3.672 31.541 31.151 1.000 40.935  0 1168 HOH A O   1 ? 
HETATM 1649 O O   . HOH C 3 .   ? -1.056 38.730 38.732 1.000 46.221  0 1169 HOH A O   1 ? 
HETATM 1650 O O   . HOH C 3 .   ? 21.082 29.833 16.405 1.000 40.504  0 1170 HOH A O   1 ? 
HETATM 1651 O O   . HOH C 3 .   ? 5.921  33.204 53.480 1.000 26.807  0 1171 HOH A O   1 ? 
HETATM 1652 O O   . HOH C 3 .   ? 20.191 29.392 37.084 1.000 48.868  0 1172 HOH A O   1 ? 
HETATM 1653 O O   . HOH C 3 .   ? 23.552 13.135 27.110 1.000 55.345  0 1173 HOH A O   1 ? 
HETATM 1654 O O   . HOH C 3 .   ? 16.012 37.470 35.563 1.000 41.863  0 1174 HOH A O   1 ? 
HETATM 1655 O O   . HOH C 3 .   ? 2.052  30.691 28.197 1.000 46.590  0 1175 HOH A O   1 ? 
HETATM 1656 O O   . HOH C 3 .   ? 16.586 18.512 37.775 1.000 33.026  0 1176 HOH A O   1 ? 
HETATM 1657 O O   . HOH C 3 .   ? 26.778 26.900 29.444 1.000 33.191  0 1177 HOH A O   1 ? 
HETATM 1658 O O   . HOH C 3 .   ? 22.720 30.747 26.150 1.000 25.270  0 1178 HOH A O   1 ? 
HETATM 1659 O O   . HOH C 3 .   ? 17.800 2.435  39.008 1.000 37.899  0 1179 HOH A O   1 ? 
HETATM 1660 O O   . HOH C 3 .   ? 3.880  43.457 41.502 1.000 38.386  0 1180 HOH A O   1 ? 
HETATM 1661 O O   . HOH C 3 .   ? 10.331 29.655 13.853 1.000 30.054  0 1181 HOH A O   1 ? 
HETATM 1662 O O   . HOH C 3 .   ? 14.617 42.530 48.769 1.000 37.691  0 1182 HOH A O   1 ? 
HETATM 1663 O O   . HOH C 3 .   ? -2.404 29.689 44.598 1.000 35.186  0 1183 HOH A O   1 ? 
HETATM 1664 O O   . HOH C 3 .   ? 18.361 25.939 33.527 1.000 31.898  0 1184 HOH A O   1 ? 
HETATM 1665 O O   . HOH C 3 .   ? 11.120 30.595 43.663 1.000 37.840  0 1185 HOH A O   1 ? 
HETATM 1666 O O   . HOH C 3 .   ? 10.897 29.118 48.130 1.000 35.670  0 1186 HOH A O   1 ? 
HETATM 1667 O O   . HOH C 3 .   ? 10.777 10.155 23.425 1.000 36.776  0 1187 HOH A O   1 ? 
HETATM 1668 O O   . HOH C 3 .   ? 7.734  39.994 30.683 1.000 43.102  0 1188 HOH A O   1 ? 
HETATM 1669 O O   . HOH C 3 .   ? 3.634  26.683 39.809 1.000 23.273  0 1189 HOH A O   1 ? 
HETATM 1670 O O   . HOH C 3 .   ? 16.000 0.063  33.108 1.000 50.199  0 1190 HOH A O   1 ? 
HETATM 1671 O O   . HOH C 3 .   ? 24.087 32.979 31.995 1.000 43.568  0 1191 HOH A O   1 ? 
HETATM 1672 O O   . HOH C 3 .   ? 8.924  30.807 49.616 1.000 24.752  0 1192 HOH A O   1 ? 
HETATM 1673 O O   . HOH C 3 .   ? 17.054 15.205 16.390 1.000 42.743  0 1193 HOH A O   1 ? 
HETATM 1674 O O   . HOH C 3 .   ? 12.536 15.370 39.075 1.000 36.791  0 1194 HOH A O   1 ? 
HETATM 1675 O O   . HOH C 3 .   ? 21.185 25.230 16.453 1.000 30.546  0 1195 HOH A O   1 ? 
HETATM 1676 O O   . HOH C 3 .   ? 29.402 19.456 28.693 1.000 40.576  0 1196 HOH A O   1 ? 
HETATM 1677 O O   . HOH C 3 .   ? 24.885 25.379 36.360 1.000 36.864  0 1197 HOH A O   1 ? 
HETATM 1678 O O   . HOH C 3 .   ? 19.946 18.252 15.907 1.000 45.902  0 1198 HOH A O   1 ? 
HETATM 1679 O O   . HOH C 3 .   ? 15.496 16.295 39.283 1.000 38.784  0 1199 HOH A O   1 ? 
HETATM 1680 O O   . HOH C 3 .   ? -3.512 26.031 42.461 1.000 46.677  0 1200 HOH A O   1 ? 
HETATM 1681 O O   . HOH C 3 .   ? 8.025  33.207 43.062 1.000 24.710  0 1201 HOH A O   1 ? 
HETATM 1682 O O   . HOH C 3 .   ? 11.398 41.546 37.766 1.000 37.540  0 1202 HOH A O   1 ? 
HETATM 1683 O O   . HOH C 3 .   ? 11.737 29.265 45.957 1.000 43.025  0 1203 HOH A O   1 ? 
HETATM 1684 O O   . HOH C 3 .   ? 19.929 19.727 39.196 1.000 47.267  0 1204 HOH A O   1 ? 
HETATM 1685 O O   . HOH C 3 .   ? 0.942  26.680 25.040 1.000 35.877  0 1205 HOH A O   1 ? 
HETATM 1686 O O   . HOH C 3 .   ? 27.994 26.728 22.052 1.000 38.709  0 1206 HOH A O   1 ? 
HETATM 1687 O O   . HOH C 3 .   ? 5.194  32.873 27.114 1.000 41.425  0 1207 HOH A O   1 ? 
HETATM 1688 O O   . HOH C 3 .   ? 3.276  30.464 20.336 1.000 31.951  0 1208 HOH A O   1 ? 
HETATM 1689 O O   . HOH C 3 .   ? 18.388 2.484  30.118 1.000 54.607  0 1209 HOH A O   1 ? 
HETATM 1690 O O   . HOH C 3 .   ? 18.664 38.605 52.148 1.000 33.369  0 1210 HOH A O   1 ? 
HETATM 1691 O O   . HOH C 3 .   ? 25.725 35.866 27.255 1.000 46.767  0 1211 HOH A O   1 ? 
HETATM 1692 O O   . HOH C 3 .   ? 11.047 33.802 16.211 1.000 36.475  0 1212 HOH A O   1 ? 
HETATM 1693 O O   . HOH C 3 .   ? 24.041 12.276 37.022 1.000 43.174  0 1213 HOH A O   1 ? 
HETATM 1694 O O   . HOH C 3 .   ? 1.494  9.172  37.008 1.000 48.581  0 1214 HOH A O   1 ? 
HETATM 1695 O O   . HOH C 3 .   ? 16.107 1.922  36.509 1.000 42.609  0 1215 HOH A O   1 ? 
HETATM 1696 O O   . HOH C 3 .   ? -1.064 28.539 49.632 1.000 49.528  0 1216 HOH A O   1 ? 
HETATM 1697 O O   . HOH C 3 .   ? 0.376  43.175 38.921 1.000 49.961  0 1217 HOH A O   1 ? 
HETATM 1698 O O   . HOH C 3 .   ? 11.704 25.093 10.185 1.000 30.911  0 1218 HOH A O   1 ? 
HETATM 1699 O O   . HOH C 3 .   ? 10.478 35.116 21.391 1.000 44.764  0 1219 HOH A O   1 ? 
HETATM 1700 O O   . HOH C 3 .   ? 22.366 19.283 17.920 1.000 60.499  0 1220 HOH A O   1 ? 
HETATM 1701 O O   . HOH C 3 .   ? 13.138 34.705 18.083 1.000 48.739  0 1221 HOH A O   1 ? 
HETATM 1702 O O   . HOH C 3 .   ? 23.330 23.489 16.519 1.000 47.590  0 1222 HOH A O   1 ? 
HETATM 1703 O O   . HOH C 3 .   ? 29.185 27.687 30.476 1.000 49.430  0 1223 HOH A O   1 ? 
HETATM 1704 O O   . HOH C 3 .   ? 20.178 31.882 38.717 1.000 56.400  0 1224 HOH A O   1 ? 
HETATM 1705 O O   . HOH C 3 .   ? 18.092 26.338 37.037 1.000 47.914  0 1225 HOH A O   1 ? 
HETATM 1706 O O   . HOH C 3 .   ? 0.783  27.417 47.596 1.000 43.676  0 1226 HOH A O   1 ? 
HETATM 1707 O O   . HOH C 3 .   ? 1.592  29.165 23.800 1.000 52.837  0 1227 HOH A O   1 ? 
HETATM 1708 O O   . HOH C 3 .   ? -1.519 27.889 46.391 1.000 48.510  0 1228 HOH A O   1 ? 
# 
