data_9FXT
# 
_entry.id   9FXT 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FXT         pdb_00009fxt 10.2210/pdb9fxt/pdb 
WWPDB D_1292139765 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FXT 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          9FY8 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jereno@cicbiogune.es 
_pdbx_contact_author.name_first         June 
_pdbx_contact_author.name_last          'Ereno Orbea' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8982-1857 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Laugieri, M.E.'      1 ? 
'Ereno Orbea, J.'     2 ? 
'Jimenez Barbero, J.' 3 ? 
'Oyenarte, I.'        4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            5 
_citation.language                  ? 
_citation.page_first                225 
_citation.page_last                 236 
_citation.title                     'Decoding the Molecular Basis of the Specificity of an Anti-sTn Antibody.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.4c00921 
_citation.pdbx_database_id_PubMed   39886580 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Soares, C.O.'        1  ?                   
primary 'Laugieri, M.E.'      2  ?                   
primary 'Grosso, A.S.'        3  ?                   
primary 'Natale, M.'          4  ?                   
primary 'Coelho, H.'          5  0000-0003-1992-8557 
primary 'Behren, S.'          6  ?                   
primary 'Yu, J.'              7  ?                   
primary 'Cai, H.'             8  0000-0002-5394-8167 
primary 'Franconetti, A.'     9  ?                   
primary 'Oyenarte, I.'        10 ?                   
primary 'Magnasco, M.'        11 ?                   
primary 'Gimeno, A.'          12 0000-0001-9668-2605 
primary 'Ramos, N.'           13 ?                   
primary 'Chai, W.'            14 0000-0003-2977-5347 
primary 'Corzana, F.'         15 0000-0001-5597-8127 
primary 'Westerlind, U.'      16 ?                   
primary 'Jimenez-Barbero, J.' 17 0000-0001-5421-8513 
primary 'Palma, A.S.'         18 ?                   
primary 'Videira, P.A.'       19 ?                   
primary 'Ereno-Orbea, J.'     20 0000-0002-5076-2105 
primary 'Marcelo, F.'         21 0000-0001-5049-8511 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'L2A5 Fab Heavy Chain'                                                             23231.879 2   ? ? ? ? 
2 polymer     man 'Anti kappa Variable Heavy Chain'                                                  12155.135 2   ? ? ? ? 
3 polymer     man 'L2A5 Fab Light Chain'                                                             23313.918 2   ? ? ? ? 
4 branched    man 'N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-galactopyranose' 512.463   2   ? ? ? ? 
5 non-polymer syn SERINE                                                                             105.093   2   ? ? ? ? 
6 non-polymer syn GLYCEROL                                                                           92.094    8   ? ? ? ? 
7 non-polymer syn 'DI(HYDROXYETHYL)ETHER'                                                            106.120   2   ? ? ? ? 
8 water       nat water                                                                              18.015    217 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVQLQESGPGLVKPSQSLSLTCSVIGYSITSGYYWNWIRQFPGNKLEWMGSINYDGSNIYNPSLKDRISITRDTSKNQFF
LKLNSVTTEDTATYYCARGGDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALT
SGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC
;
;EVQLQESGPGLVKPSQSLSLTCSVIGYSITSGYYWNWIRQFPGNKLEWMGSINYDGSNIYNPSLKDRISITRDTSKNQFF
LKLNSVTTEDTATYYCARGGDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALT
SGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC
;
H,I ? 
2 'polypeptide(L)' no no 
;(UNK)VQL(UNK)(UNK)SGGG(UNK)VQ(UNK)G(UNK)SL(UNK)LSC(UNK)A(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)W(UNK)RQ(UNK)PG(UNK)(UNK)RE(UNK)V(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)DS(UNK)(UNK)GRFT(UNK)S
(UNK)D(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)LQ(UNK)(UNK)(UNK)L(UNK)(UNK)(UNK)D(UNK)
A(UNK)YYC(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)W
G(UNK)GT(UNK)VTVSSHHHHHH
;
;XVQLXXSGGGXVQXGXSLXLSCXAXXXXXXXXXXXWXRQXPGXXREXVXXXXXXXXXXXXXDSXXGRFTXSXDXXXXXXX
LQXXXLXXXDXAXYYCXXXXXXXXXXXXXXWGXGTXVTVSSHHHHHH
;
K,V ? 
3 'polypeptide(L)' no no 
;DIVLTQTPAIMSASPGEKVTLTCSASSSVSYMHWFQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAE
DAAAYYCQQWSSDPPMLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;DIVLTQTPAIMSASPGEKVTLTCSASSSVSYMHWFQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAE
DAAAYYCQQWSSDPPMLTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L,M ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
5 SERINE                  SER 
6 GLYCEROL                GOL 
7 'DI(HYDROXYETHYL)ETHER' PEG 
8 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   GLN n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   PRO n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  LYS n 
1 14  PRO n 
1 15  SER n 
1 16  GLN n 
1 17  SER n 
1 18  LEU n 
1 19  SER n 
1 20  LEU n 
1 21  THR n 
1 22  CYS n 
1 23  SER n 
1 24  VAL n 
1 25  ILE n 
1 26  GLY n 
1 27  TYR n 
1 28  SER n 
1 29  ILE n 
1 30  THR n 
1 31  SER n 
1 32  GLY n 
1 33  TYR n 
1 34  TYR n 
1 35  TRP n 
1 36  ASN n 
1 37  TRP n 
1 38  ILE n 
1 39  ARG n 
1 40  GLN n 
1 41  PHE n 
1 42  PRO n 
1 43  GLY n 
1 44  ASN n 
1 45  LYS n 
1 46  LEU n 
1 47  GLU n 
1 48  TRP n 
1 49  MET n 
1 50  GLY n 
1 51  SER n 
1 52  ILE n 
1 53  ASN n 
1 54  TYR n 
1 55  ASP n 
1 56  GLY n 
1 57  SER n 
1 58  ASN n 
1 59  ILE n 
1 60  TYR n 
1 61  ASN n 
1 62  PRO n 
1 63  SER n 
1 64  LEU n 
1 65  LYS n 
1 66  ASP n 
1 67  ARG n 
1 68  ILE n 
1 69  SER n 
1 70  ILE n 
1 71  THR n 
1 72  ARG n 
1 73  ASP n 
1 74  THR n 
1 75  SER n 
1 76  LYS n 
1 77  ASN n 
1 78  GLN n 
1 79  PHE n 
1 80  PHE n 
1 81  LEU n 
1 82  LYS n 
1 83  LEU n 
1 84  ASN n 
1 85  SER n 
1 86  VAL n 
1 87  THR n 
1 88  THR n 
1 89  GLU n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  THR n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  ARG n 
1 99  GLY n 
1 100 GLY n 
1 101 ASP n 
1 102 TYR n 
1 103 TRP n 
1 104 GLY n 
1 105 GLN n 
1 106 GLY n 
1 107 THR n 
1 108 SER n 
1 109 VAL n 
1 110 THR n 
1 111 VAL n 
1 112 SER n 
1 113 SER n 
1 114 ALA n 
1 115 SER n 
1 116 THR n 
1 117 LYS n 
1 118 GLY n 
1 119 PRO n 
1 120 SER n 
1 121 VAL n 
1 122 PHE n 
1 123 PRO n 
1 124 LEU n 
1 125 ALA n 
1 126 PRO n 
1 127 SER n 
1 128 SER n 
1 129 LYS n 
1 130 SER n 
1 131 THR n 
1 132 SER n 
1 133 GLY n 
1 134 GLY n 
1 135 THR n 
1 136 ALA n 
1 137 ALA n 
1 138 LEU n 
1 139 GLY n 
1 140 CYS n 
1 141 LEU n 
1 142 VAL n 
1 143 LYS n 
1 144 ASP n 
1 145 TYR n 
1 146 PHE n 
1 147 PRO n 
1 148 GLU n 
1 149 PRO n 
1 150 VAL n 
1 151 THR n 
1 152 VAL n 
1 153 SER n 
1 154 TRP n 
1 155 ASN n 
1 156 SER n 
1 157 GLY n 
1 158 ALA n 
1 159 LEU n 
1 160 THR n 
1 161 SER n 
1 162 GLY n 
1 163 VAL n 
1 164 HIS n 
1 165 THR n 
1 166 PHE n 
1 167 PRO n 
1 168 ALA n 
1 169 VAL n 
1 170 LEU n 
1 171 GLN n 
1 172 SER n 
1 173 SER n 
1 174 GLY n 
1 175 LEU n 
1 176 TYR n 
1 177 SER n 
1 178 LEU n 
1 179 SER n 
1 180 SER n 
1 181 VAL n 
1 182 VAL n 
1 183 THR n 
1 184 VAL n 
1 185 PRO n 
1 186 SER n 
1 187 SER n 
1 188 SER n 
1 189 LEU n 
1 190 GLY n 
1 191 THR n 
1 192 GLN n 
1 193 THR n 
1 194 TYR n 
1 195 ILE n 
1 196 CYS n 
1 197 ASN n 
1 198 VAL n 
1 199 ASN n 
1 200 HIS n 
1 201 LYS n 
1 202 PRO n 
1 203 SER n 
1 204 ASN n 
1 205 THR n 
1 206 LYS n 
1 207 VAL n 
1 208 ASP n 
1 209 LYS n 
1 210 ARG n 
1 211 VAL n 
1 212 GLU n 
1 213 PRO n 
1 214 LYS n 
1 215 SER n 
1 216 CYS n 
2 1   UNK n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   UNK n 
2 6   UNK n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  UNK n 
2 12  VAL n 
2 13  GLN n 
2 14  UNK n 
2 15  GLY n 
2 16  UNK n 
2 17  SER n 
2 18  LEU n 
2 19  UNK n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  UNK n 
2 24  ALA n 
2 25  UNK n 
2 26  UNK n 
2 27  UNK n 
2 28  UNK n 
2 29  UNK n 
2 30  UNK n 
2 31  UNK n 
2 32  UNK n 
2 33  UNK n 
2 34  UNK n 
2 35  UNK n 
2 36  TRP n 
2 37  UNK n 
2 38  ARG n 
2 39  GLN n 
2 40  UNK n 
2 41  PRO n 
2 42  GLY n 
2 43  UNK n 
2 44  UNK n 
2 45  ARG n 
2 46  GLU n 
2 47  UNK n 
2 48  VAL n 
2 49  UNK n 
2 50  UNK n 
2 51  UNK n 
2 52  UNK n 
2 53  UNK n 
2 54  UNK n 
2 55  UNK n 
2 56  UNK n 
2 57  UNK n 
2 58  UNK n 
2 59  UNK n 
2 60  UNK n 
2 61  UNK n 
2 62  ASP n 
2 63  SER n 
2 64  UNK n 
2 65  UNK n 
2 66  GLY n 
2 67  ARG n 
2 68  PHE n 
2 69  THR n 
2 70  UNK n 
2 71  SER n 
2 72  UNK n 
2 73  ASP n 
2 74  UNK n 
2 75  UNK n 
2 76  UNK n 
2 77  UNK n 
2 78  UNK n 
2 79  UNK n 
2 80  UNK n 
2 81  LEU n 
2 82  GLN n 
2 83  UNK n 
2 84  UNK n 
2 85  UNK n 
2 86  LEU n 
2 87  UNK n 
2 88  UNK n 
2 89  UNK n 
2 90  ASP n 
2 91  UNK n 
2 92  ALA n 
2 93  UNK n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  UNK n 
2 98  UNK n 
2 99  UNK n 
2 100 UNK n 
2 101 UNK n 
2 102 UNK n 
2 103 UNK n 
2 104 UNK n 
2 105 UNK n 
2 106 UNK n 
2 107 UNK n 
2 108 UNK n 
2 109 UNK n 
2 110 UNK n 
2 111 TRP n 
2 112 GLY n 
2 113 UNK n 
2 114 GLY n 
2 115 THR n 
2 116 UNK n 
2 117 VAL n 
2 118 THR n 
2 119 VAL n 
2 120 SER n 
2 121 SER n 
2 122 HIS n 
2 123 HIS n 
2 124 HIS n 
2 125 HIS n 
2 126 HIS n 
2 127 HIS n 
3 1   ASP n 
3 2   ILE n 
3 3   VAL n 
3 4   LEU n 
3 5   THR n 
3 6   GLN n 
3 7   THR n 
3 8   PRO n 
3 9   ALA n 
3 10  ILE n 
3 11  MET n 
3 12  SER n 
3 13  ALA n 
3 14  SER n 
3 15  PRO n 
3 16  GLY n 
3 17  GLU n 
3 18  LYS n 
3 19  VAL n 
3 20  THR n 
3 21  LEU n 
3 22  THR n 
3 23  CYS n 
3 24  SER n 
3 25  ALA n 
3 26  SER n 
3 27  SER n 
3 28  SER n 
3 29  VAL n 
3 30  SER n 
3 31  TYR n 
3 32  MET n 
3 33  HIS n 
3 34  TRP n 
3 35  PHE n 
3 36  GLN n 
3 37  GLN n 
3 38  LYS n 
3 39  SER n 
3 40  GLY n 
3 41  THR n 
3 42  SER n 
3 43  PRO n 
3 44  LYS n 
3 45  ARG n 
3 46  TRP n 
3 47  ILE n 
3 48  TYR n 
3 49  ASP n 
3 50  THR n 
3 51  SER n 
3 52  LYS n 
3 53  LEU n 
3 54  ALA n 
3 55  SER n 
3 56  GLY n 
3 57  VAL n 
3 58  PRO n 
3 59  ALA n 
3 60  ARG n 
3 61  PHE n 
3 62  SER n 
3 63  GLY n 
3 64  SER n 
3 65  GLY n 
3 66  SER n 
3 67  GLY n 
3 68  THR n 
3 69  SER n 
3 70  TYR n 
3 71  SER n 
3 72  LEU n 
3 73  THR n 
3 74  ILE n 
3 75  SER n 
3 76  SER n 
3 77  MET n 
3 78  GLU n 
3 79  ALA n 
3 80  GLU n 
3 81  ASP n 
3 82  ALA n 
3 83  ALA n 
3 84  ALA n 
3 85  TYR n 
3 86  TYR n 
3 87  CYS n 
3 88  GLN n 
3 89  GLN n 
3 90  TRP n 
3 91  SER n 
3 92  SER n 
3 93  ASP n 
3 94  PRO n 
3 95  PRO n 
3 96  MET n 
3 97  LEU n 
3 98  THR n 
3 99  PHE n 
3 100 GLY n 
3 101 ALA n 
3 102 GLY n 
3 103 THR n 
3 104 LYS n 
3 105 LEU n 
3 106 GLU n 
3 107 LEU n 
3 108 LYS n 
3 109 ARG n 
3 110 THR n 
3 111 VAL n 
3 112 ALA n 
3 113 ALA n 
3 114 PRO n 
3 115 SER n 
3 116 VAL n 
3 117 PHE n 
3 118 ILE n 
3 119 PHE n 
3 120 PRO n 
3 121 PRO n 
3 122 SER n 
3 123 ASP n 
3 124 GLU n 
3 125 GLN n 
3 126 LEU n 
3 127 LYS n 
3 128 SER n 
3 129 GLY n 
3 130 THR n 
3 131 ALA n 
3 132 SER n 
3 133 VAL n 
3 134 VAL n 
3 135 CYS n 
3 136 LEU n 
3 137 LEU n 
3 138 ASN n 
3 139 ASN n 
3 140 PHE n 
3 141 TYR n 
3 142 PRO n 
3 143 ARG n 
3 144 GLU n 
3 145 ALA n 
3 146 LYS n 
3 147 VAL n 
3 148 GLN n 
3 149 TRP n 
3 150 LYS n 
3 151 VAL n 
3 152 ASP n 
3 153 ASN n 
3 154 ALA n 
3 155 LEU n 
3 156 GLN n 
3 157 SER n 
3 158 GLY n 
3 159 ASN n 
3 160 SER n 
3 161 GLN n 
3 162 GLU n 
3 163 SER n 
3 164 VAL n 
3 165 THR n 
3 166 GLU n 
3 167 GLN n 
3 168 ASP n 
3 169 SER n 
3 170 LYS n 
3 171 ASP n 
3 172 SER n 
3 173 THR n 
3 174 TYR n 
3 175 SER n 
3 176 LEU n 
3 177 SER n 
3 178 SER n 
3 179 THR n 
3 180 LEU n 
3 181 THR n 
3 182 LEU n 
3 183 SER n 
3 184 LYS n 
3 185 ALA n 
3 186 ASP n 
3 187 TYR n 
3 188 GLU n 
3 189 LYS n 
3 190 HIS n 
3 191 LYS n 
3 192 VAL n 
3 193 TYR n 
3 194 ALA n 
3 195 CYS n 
3 196 GLU n 
3 197 VAL n 
3 198 THR n 
3 199 HIS n 
3 200 GLN n 
3 201 GLY n 
3 202 LEU n 
3 203 SER n 
3 204 SER n 
3 205 PRO n 
3 206 VAL n 
3 207 THR n 
3 208 LYS n 
3 209 SER n 
3 210 PHE n 
3 211 ASN n 
3 212 ARG n 
3 213 GLY n 
3 214 GLU n 
3 215 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 216 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 127 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 215 ? ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   4 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 4 DNeup5Aca2-6DGalpNAca1-                                                           'Glycam Condensed Sequence' GMML       1.0   
2 4 'WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2/a6-b2' WURCS                       PDB2Glycan 1.1.0 
3 4 '[]{[(3+1)][a-D-GalpNAc]{[(6+2)][a-D-Neup5Ac]{}}}'                                LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  4 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  SIA 
_pdbx_entity_branch_link.atom_id_1                  C2 
_pdbx_entity_branch_link.leaving_atom_id_1          O2 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  A2G 
_pdbx_entity_branch_link.atom_id_2                  O6 
_pdbx_entity_branch_link.leaving_atom_id_2          HO6 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A2G 'D-saccharide, alpha linking' . 2-acetamido-2-deoxy-alpha-D-galactopyranose 
;N-acetyl-alpha-D-galactosamine; 2-acetamido-2-deoxy-alpha-D-galactose; 2-acetamido-2-deoxy-D-galactose; 2-acetamido-2-deoxy-galactose; N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE
;
'C8 H15 N O6'    221.208 
ALA 'L-peptide linking'           y ALANINE                                     ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                    ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                                  ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                             ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'           y CYSTEINE                                    ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE                                   ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                             ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                     ? 'C2 H5 N O2'     75.067  
GOL non-polymer                   . GLYCEROL                                    'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       
92.094  
HIS 'L-peptide linking'           y HISTIDINE                                   ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                                       ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                                  ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                     ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                      ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                                  ? 'C5 H11 N O2 S'  149.211 
PEG non-polymer                   . 'DI(HYDROXYETHYL)ETHER'                     ? 'C4 H10 O3'      106.120 
PHE 'L-peptide linking'           y PHENYLALANINE                               ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                     ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                      ? 'C3 H7 N O3'     105.093 
SIA 'D-saccharide, alpha linking' . 'N-acetyl-alpha-neuraminic acid'            
'N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID' 'C11 H19 N O9'   309.270 
THR 'L-peptide linking'           y THREONINE                                   ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                                  ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                    ? 'C9 H11 N O3'    181.189 
UNK 'L-peptide linking'           . UNKNOWN                                     ? 'C4 H9 N O2'     103.120 
VAL 'L-peptide linking'           y VALINE                                      ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
A2G 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGalpNAca                        
A2G 'COMMON NAME'                         GMML     1.0 N-acetyl-a-D-galactopyranosamine 
A2G 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-GalpNAc                      
A2G 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GalNAc                           
SIA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DNeup5Aca                        
SIA 'COMMON NAME'                         GMML     1.0 'N-acetyl-a-D-neuraminic acid'   
SIA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Neup5Ac                      
SIA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Neu5Ac                           
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   ?   ?   ?   H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   GLN 5   5   5   GLN GLN H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   PRO 9   9   9   PRO PRO H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  LYS 13  13  13  LYS LYS H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  SER 15  15  15  SER SER H . n 
A 1 16  GLN 16  16  16  GLN GLN H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  SER 19  19  19  SER SER H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  THR 21  21  21  THR THR H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  SER 23  23  23  SER SER H . n 
A 1 24  VAL 24  24  24  VAL VAL H . n 
A 1 25  ILE 25  25  ?   ?   ?   H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  TYR 27  27  27  TYR TYR H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  ILE 29  29  29  ILE ILE H . n 
A 1 30  THR 30  30  30  THR THR H . n 
A 1 31  SER 31  31  ?   ?   ?   H . n 
A 1 32  GLY 32  32  ?   ?   ?   H . n 
A 1 33  TYR 33  33  ?   ?   ?   H . n 
A 1 34  TYR 34  34  34  TYR TYR H . n 
A 1 35  TRP 35  35  35  TRP TRP H . n 
A 1 36  ASN 36  35  35  ASN ASN H A n 
A 1 37  TRP 37  36  36  TRP TRP H . n 
A 1 38  ILE 38  37  37  ILE ILE H . n 
A 1 39  ARG 39  38  38  ARG ARG H . n 
A 1 40  GLN 40  39  39  GLN GLN H . n 
A 1 41  PHE 41  40  40  PHE PHE H . n 
A 1 42  PRO 42  41  41  PRO PRO H . n 
A 1 43  GLY 43  42  42  GLY GLY H . n 
A 1 44  ASN 44  43  43  ASN ASN H . n 
A 1 45  LYS 45  44  44  LYS LYS H . n 
A 1 46  LEU 46  45  45  LEU LEU H . n 
A 1 47  GLU 47  46  46  GLU GLU H . n 
A 1 48  TRP 48  47  47  TRP TRP H . n 
A 1 49  MET 49  48  48  MET MET H . n 
A 1 50  GLY 50  49  49  GLY GLY H . n 
A 1 51  SER 51  50  50  SER SER H . n 
A 1 52  ILE 52  51  51  ILE ILE H . n 
A 1 53  ASN 53  52  52  ASN ASN H . n 
A 1 54  TYR 54  53  ?   ?   ?   H . n 
A 1 55  ASP 55  54  ?   ?   ?   H . n 
A 1 56  GLY 56  55  ?   ?   ?   H . n 
A 1 57  SER 57  56  ?   ?   ?   H . n 
A 1 58  ASN 58  57  ?   ?   ?   H . n 
A 1 59  ILE 59  58  ?   ?   ?   H . n 
A 1 60  TYR 60  59  59  TYR TYR H . n 
A 1 61  ASN 61  60  60  ASN ASN H . n 
A 1 62  PRO 62  61  61  PRO PRO H . n 
A 1 63  SER 63  62  62  SER SER H . n 
A 1 64  LEU 64  63  63  LEU LEU H . n 
A 1 65  LYS 65  64  64  LYS LYS H . n 
A 1 66  ASP 66  65  65  ASP ASP H . n 
A 1 67  ARG 67  66  66  ARG ARG H . n 
A 1 68  ILE 68  67  67  ILE ILE H . n 
A 1 69  SER 69  68  ?   ?   ?   H . n 
A 1 70  ILE 70  69  69  ILE ILE H . n 
A 1 71  THR 71  70  70  THR THR H . n 
A 1 72  ARG 72  71  71  ARG ARG H . n 
A 1 73  ASP 73  72  72  ASP ASP H . n 
A 1 74  THR 74  73  73  THR THR H . n 
A 1 75  SER 75  74  74  SER SER H . n 
A 1 76  LYS 76  75  75  LYS LYS H . n 
A 1 77  ASN 77  76  76  ASN ASN H . n 
A 1 78  GLN 78  77  77  GLN GLN H . n 
A 1 79  PHE 79  78  78  PHE PHE H . n 
A 1 80  PHE 80  79  79  PHE PHE H . n 
A 1 81  LEU 81  80  80  LEU LEU H . n 
A 1 82  LYS 82  81  81  LYS LYS H . n 
A 1 83  LEU 83  82  82  LEU LEU H . n 
A 1 84  ASN 84  82  82  ASN ASN H A n 
A 1 85  SER 85  82  82  SER SER H B n 
A 1 86  VAL 86  82  82  VAL VAL H C n 
A 1 87  THR 87  83  83  THR THR H . n 
A 1 88  THR 88  84  84  THR THR H . n 
A 1 89  GLU 89  85  85  GLU GLU H . n 
A 1 90  ASP 90  86  86  ASP ASP H . n 
A 1 91  THR 91  87  87  THR THR H . n 
A 1 92  ALA 92  88  88  ALA ALA H . n 
A 1 93  THR 93  89  89  THR THR H . n 
A 1 94  TYR 94  90  90  TYR TYR H . n 
A 1 95  TYR 95  91  91  TYR TYR H . n 
A 1 96  CYS 96  92  92  CYS CYS H . n 
A 1 97  ALA 97  93  93  ALA ALA H . n 
A 1 98  ARG 98  94  94  ARG ARG H . n 
A 1 99  GLY 99  95  95  GLY GLY H . n 
A 1 100 GLY 100 96  96  GLY GLY H . n 
A 1 101 ASP 101 101 101 ASP ASP H . n 
A 1 102 TYR 102 102 102 TYR TYR H . n 
A 1 103 TRP 103 103 103 TRP TRP H . n 
A 1 104 GLY 104 104 104 GLY GLY H . n 
A 1 105 GLN 105 105 105 GLN GLN H . n 
A 1 106 GLY 106 106 106 GLY GLY H . n 
A 1 107 THR 107 107 107 THR THR H . n 
A 1 108 SER 108 108 108 SER SER H . n 
A 1 109 VAL 109 109 109 VAL VAL H . n 
A 1 110 THR 110 110 110 THR THR H . n 
A 1 111 VAL 111 111 111 VAL VAL H . n 
A 1 112 SER 112 112 112 SER SER H . n 
A 1 113 SER 113 113 113 SER SER H . n 
A 1 114 ALA 114 114 114 ALA ALA H . n 
A 1 115 SER 115 115 115 SER SER H . n 
A 1 116 THR 116 116 116 THR THR H . n 
A 1 117 LYS 117 117 117 LYS LYS H . n 
A 1 118 GLY 118 118 118 GLY GLY H . n 
A 1 119 PRO 119 119 119 PRO PRO H . n 
A 1 120 SER 120 120 120 SER SER H . n 
A 1 121 VAL 121 121 121 VAL VAL H . n 
A 1 122 PHE 122 122 122 PHE PHE H . n 
A 1 123 PRO 123 123 123 PRO PRO H . n 
A 1 124 LEU 124 124 124 LEU LEU H . n 
A 1 125 ALA 125 125 125 ALA ALA H . n 
A 1 126 PRO 126 126 126 PRO PRO H . n 
A 1 127 SER 127 127 127 SER SER H . n 
A 1 128 SER 128 128 128 SER SER H . n 
A 1 129 LYS 129 129 ?   ?   ?   H . n 
A 1 130 SER 130 130 ?   ?   ?   H . n 
A 1 131 THR 131 131 ?   ?   ?   H . n 
A 1 132 SER 132 132 ?   ?   ?   H . n 
A 1 133 GLY 133 133 133 GLY GLY H . n 
A 1 134 GLY 134 134 134 GLY GLY H . n 
A 1 135 THR 135 135 135 THR THR H . n 
A 1 136 ALA 136 136 136 ALA ALA H . n 
A 1 137 ALA 137 137 137 ALA ALA H . n 
A 1 138 LEU 138 138 138 LEU LEU H . n 
A 1 139 GLY 139 139 139 GLY GLY H . n 
A 1 140 CYS 140 140 140 CYS CYS H . n 
A 1 141 LEU 141 141 141 LEU LEU H . n 
A 1 142 VAL 142 142 142 VAL VAL H . n 
A 1 143 LYS 143 143 143 LYS LYS H . n 
A 1 144 ASP 144 144 144 ASP ASP H . n 
A 1 145 TYR 145 145 145 TYR TYR H . n 
A 1 146 PHE 146 146 146 PHE PHE H . n 
A 1 147 PRO 147 147 147 PRO PRO H . n 
A 1 148 GLU 148 148 148 GLU GLU H . n 
A 1 149 PRO 149 149 149 PRO PRO H . n 
A 1 150 VAL 150 150 150 VAL VAL H . n 
A 1 151 THR 151 151 151 THR THR H . n 
A 1 152 VAL 152 152 152 VAL VAL H . n 
A 1 153 SER 153 153 153 SER SER H . n 
A 1 154 TRP 154 154 154 TRP TRP H . n 
A 1 155 ASN 155 155 155 ASN ASN H . n 
A 1 156 SER 156 156 156 SER SER H . n 
A 1 157 GLY 157 157 157 GLY GLY H . n 
A 1 158 ALA 158 158 158 ALA ALA H . n 
A 1 159 LEU 159 159 159 LEU LEU H . n 
A 1 160 THR 160 160 160 THR THR H . n 
A 1 161 SER 161 161 161 SER SER H . n 
A 1 162 GLY 162 162 162 GLY GLY H . n 
A 1 163 VAL 163 163 163 VAL VAL H . n 
A 1 164 HIS 164 164 164 HIS HIS H . n 
A 1 165 THR 165 165 165 THR THR H . n 
A 1 166 PHE 166 166 166 PHE PHE H . n 
A 1 167 PRO 167 167 167 PRO PRO H . n 
A 1 168 ALA 168 168 168 ALA ALA H . n 
A 1 169 VAL 169 169 169 VAL VAL H . n 
A 1 170 LEU 170 170 170 LEU LEU H . n 
A 1 171 GLN 171 171 171 GLN GLN H . n 
A 1 172 SER 172 172 172 SER SER H . n 
A 1 173 SER 173 173 173 SER SER H . n 
A 1 174 GLY 174 174 174 GLY GLY H . n 
A 1 175 LEU 175 175 175 LEU LEU H . n 
A 1 176 TYR 176 176 176 TYR TYR H . n 
A 1 177 SER 177 177 177 SER SER H . n 
A 1 178 LEU 178 178 178 LEU LEU H . n 
A 1 179 SER 179 179 179 SER SER H . n 
A 1 180 SER 180 180 180 SER SER H . n 
A 1 181 VAL 181 181 181 VAL VAL H . n 
A 1 182 VAL 182 182 182 VAL VAL H . n 
A 1 183 THR 183 183 183 THR THR H . n 
A 1 184 VAL 184 184 184 VAL VAL H . n 
A 1 185 PRO 185 185 185 PRO PRO H . n 
A 1 186 SER 186 186 186 SER SER H . n 
A 1 187 SER 187 187 187 SER SER H . n 
A 1 188 SER 188 188 188 SER SER H . n 
A 1 189 LEU 189 189 189 LEU LEU H . n 
A 1 190 GLY 190 190 190 GLY GLY H . n 
A 1 191 THR 191 191 191 THR THR H . n 
A 1 192 GLN 192 192 192 GLN GLN H . n 
A 1 193 THR 193 193 193 THR THR H . n 
A 1 194 TYR 194 194 194 TYR TYR H . n 
A 1 195 ILE 195 195 195 ILE ILE H . n 
A 1 196 CYS 196 196 196 CYS CYS H . n 
A 1 197 ASN 197 197 197 ASN ASN H . n 
A 1 198 VAL 198 198 198 VAL VAL H . n 
A 1 199 ASN 199 199 199 ASN ASN H . n 
A 1 200 HIS 200 200 200 HIS HIS H . n 
A 1 201 LYS 201 201 201 LYS LYS H . n 
A 1 202 PRO 202 202 202 PRO PRO H . n 
A 1 203 SER 203 203 203 SER SER H . n 
A 1 204 ASN 204 204 204 ASN ASN H . n 
A 1 205 THR 205 205 205 THR THR H . n 
A 1 206 LYS 206 206 206 LYS LYS H . n 
A 1 207 VAL 207 207 207 VAL VAL H . n 
A 1 208 ASP 208 208 208 ASP ASP H . n 
A 1 209 LYS 209 209 209 LYS LYS H . n 
A 1 210 ARG 210 210 210 ARG ARG H . n 
A 1 211 VAL 211 211 211 VAL VAL H . n 
A 1 212 GLU 212 212 212 GLU GLU H . n 
A 1 213 PRO 213 213 213 PRO PRO H . n 
A 1 214 LYS 214 214 214 LYS LYS H . n 
A 1 215 SER 215 215 ?   ?   ?   H . n 
A 1 216 CYS 216 216 ?   ?   ?   H . n 
B 1 1   GLU 1   1   1   GLU GLU I . n 
B 1 2   VAL 2   2   2   VAL VAL I . n 
B 1 3   GLN 3   3   3   GLN GLN I . n 
B 1 4   LEU 4   4   4   LEU LEU I . n 
B 1 5   GLN 5   5   5   GLN GLN I . n 
B 1 6   GLU 6   6   6   GLU GLU I . n 
B 1 7   SER 7   7   7   SER SER I . n 
B 1 8   GLY 8   8   8   GLY GLY I . n 
B 1 9   PRO 9   9   9   PRO PRO I . n 
B 1 10  GLY 10  10  10  GLY GLY I . n 
B 1 11  LEU 11  11  11  LEU LEU I . n 
B 1 12  VAL 12  12  12  VAL VAL I . n 
B 1 13  LYS 13  13  13  LYS LYS I . n 
B 1 14  PRO 14  14  14  PRO PRO I . n 
B 1 15  SER 15  15  15  SER SER I . n 
B 1 16  GLN 16  16  16  GLN GLN I . n 
B 1 17  SER 17  17  17  SER SER I . n 
B 1 18  LEU 18  18  18  LEU LEU I . n 
B 1 19  SER 19  19  19  SER SER I . n 
B 1 20  LEU 20  20  20  LEU LEU I . n 
B 1 21  THR 21  21  21  THR THR I . n 
B 1 22  CYS 22  22  22  CYS CYS I . n 
B 1 23  SER 23  23  23  SER SER I . n 
B 1 24  VAL 24  24  24  VAL VAL I . n 
B 1 25  ILE 25  25  25  ILE ILE I . n 
B 1 26  GLY 26  26  26  GLY GLY I . n 
B 1 27  TYR 27  27  27  TYR TYR I . n 
B 1 28  SER 28  28  28  SER SER I . n 
B 1 29  ILE 29  29  29  ILE ILE I . n 
B 1 30  THR 30  30  30  THR THR I . n 
B 1 31  SER 31  31  31  SER SER I . n 
B 1 32  GLY 32  32  32  GLY GLY I . n 
B 1 33  TYR 33  33  33  TYR TYR I . n 
B 1 34  TYR 34  34  34  TYR TYR I . n 
B 1 35  TRP 35  35  35  TRP TRP I . n 
B 1 36  ASN 36  35  35  ASN ASN I A n 
B 1 37  TRP 37  36  36  TRP TRP I . n 
B 1 38  ILE 38  37  37  ILE ILE I . n 
B 1 39  ARG 39  38  38  ARG ARG I . n 
B 1 40  GLN 40  39  39  GLN GLN I . n 
B 1 41  PHE 41  40  40  PHE PHE I . n 
B 1 42  PRO 42  41  41  PRO PRO I . n 
B 1 43  GLY 43  42  42  GLY GLY I . n 
B 1 44  ASN 44  43  43  ASN ASN I . n 
B 1 45  LYS 45  44  44  LYS LYS I . n 
B 1 46  LEU 46  45  45  LEU LEU I . n 
B 1 47  GLU 47  46  46  GLU GLU I . n 
B 1 48  TRP 48  47  47  TRP TRP I . n 
B 1 49  MET 49  48  48  MET MET I . n 
B 1 50  GLY 50  49  49  GLY GLY I . n 
B 1 51  SER 51  50  50  SER SER I . n 
B 1 52  ILE 52  51  51  ILE ILE I . n 
B 1 53  ASN 53  52  52  ASN ASN I . n 
B 1 54  TYR 54  53  53  TYR TYR I . n 
B 1 55  ASP 55  54  54  ASP ASP I . n 
B 1 56  GLY 56  55  55  GLY GLY I . n 
B 1 57  SER 57  56  56  SER SER I . n 
B 1 58  ASN 58  57  57  ASN ASN I . n 
B 1 59  ILE 59  58  58  ILE ILE I . n 
B 1 60  TYR 60  59  59  TYR TYR I . n 
B 1 61  ASN 61  60  60  ASN ASN I . n 
B 1 62  PRO 62  61  61  PRO PRO I . n 
B 1 63  SER 63  62  62  SER SER I . n 
B 1 64  LEU 64  63  63  LEU LEU I . n 
B 1 65  LYS 65  64  64  LYS LYS I . n 
B 1 66  ASP 66  65  65  ASP ASP I . n 
B 1 67  ARG 67  66  66  ARG ARG I . n 
B 1 68  ILE 68  67  67  ILE ILE I . n 
B 1 69  SER 69  68  68  SER SER I . n 
B 1 70  ILE 70  69  69  ILE ILE I . n 
B 1 71  THR 71  70  70  THR THR I . n 
B 1 72  ARG 72  71  71  ARG ARG I . n 
B 1 73  ASP 73  72  72  ASP ASP I . n 
B 1 74  THR 74  73  73  THR THR I . n 
B 1 75  SER 75  74  74  SER SER I . n 
B 1 76  LYS 76  75  75  LYS LYS I . n 
B 1 77  ASN 77  76  76  ASN ASN I . n 
B 1 78  GLN 78  77  77  GLN GLN I . n 
B 1 79  PHE 79  78  78  PHE PHE I . n 
B 1 80  PHE 80  79  79  PHE PHE I . n 
B 1 81  LEU 81  80  80  LEU LEU I . n 
B 1 82  LYS 82  81  81  LYS LYS I . n 
B 1 83  LEU 83  82  82  LEU LEU I . n 
B 1 84  ASN 84  82  82  ASN ASN I A n 
B 1 85  SER 85  82  82  SER SER I B n 
B 1 86  VAL 86  82  82  VAL VAL I C n 
B 1 87  THR 87  83  83  THR THR I . n 
B 1 88  THR 88  84  84  THR THR I . n 
B 1 89  GLU 89  85  85  GLU GLU I . n 
B 1 90  ASP 90  86  86  ASP ASP I . n 
B 1 91  THR 91  87  87  THR THR I . n 
B 1 92  ALA 92  88  88  ALA ALA I . n 
B 1 93  THR 93  89  89  THR THR I . n 
B 1 94  TYR 94  90  90  TYR TYR I . n 
B 1 95  TYR 95  91  91  TYR TYR I . n 
B 1 96  CYS 96  92  92  CYS CYS I . n 
B 1 97  ALA 97  93  93  ALA ALA I . n 
B 1 98  ARG 98  94  94  ARG ARG I . n 
B 1 99  GLY 99  95  95  GLY GLY I . n 
B 1 100 GLY 100 96  96  GLY GLY I . n 
B 1 101 ASP 101 101 101 ASP ASP I . n 
B 1 102 TYR 102 102 102 TYR TYR I . n 
B 1 103 TRP 103 103 103 TRP TRP I . n 
B 1 104 GLY 104 104 104 GLY GLY I . n 
B 1 105 GLN 105 105 105 GLN GLN I . n 
B 1 106 GLY 106 106 106 GLY GLY I . n 
B 1 107 THR 107 107 107 THR THR I . n 
B 1 108 SER 108 108 108 SER SER I . n 
B 1 109 VAL 109 109 109 VAL VAL I . n 
B 1 110 THR 110 110 110 THR THR I . n 
B 1 111 VAL 111 111 111 VAL VAL I . n 
B 1 112 SER 112 112 112 SER SER I . n 
B 1 113 SER 113 113 113 SER SER I . n 
B 1 114 ALA 114 114 114 ALA ALA I . n 
B 1 115 SER 115 115 115 SER SER I . n 
B 1 116 THR 116 116 116 THR THR I . n 
B 1 117 LYS 117 117 117 LYS LYS I . n 
B 1 118 GLY 118 118 118 GLY GLY I . n 
B 1 119 PRO 119 119 119 PRO PRO I . n 
B 1 120 SER 120 120 120 SER SER I . n 
B 1 121 VAL 121 121 121 VAL VAL I . n 
B 1 122 PHE 122 122 122 PHE PHE I . n 
B 1 123 PRO 123 123 123 PRO PRO I . n 
B 1 124 LEU 124 124 124 LEU LEU I . n 
B 1 125 ALA 125 125 125 ALA ALA I . n 
B 1 126 PRO 126 126 126 PRO PRO I . n 
B 1 127 SER 127 127 127 SER SER I . n 
B 1 128 SER 128 128 128 SER SER I . n 
B 1 129 LYS 129 129 129 LYS LYS I . n 
B 1 130 SER 130 130 130 SER SER I . n 
B 1 131 THR 131 131 131 THR THR I . n 
B 1 132 SER 132 132 132 SER SER I . n 
B 1 133 GLY 133 133 133 GLY GLY I . n 
B 1 134 GLY 134 134 134 GLY GLY I . n 
B 1 135 THR 135 135 135 THR THR I . n 
B 1 136 ALA 136 136 136 ALA ALA I . n 
B 1 137 ALA 137 137 137 ALA ALA I . n 
B 1 138 LEU 138 138 138 LEU LEU I . n 
B 1 139 GLY 139 139 139 GLY GLY I . n 
B 1 140 CYS 140 140 140 CYS CYS I . n 
B 1 141 LEU 141 141 141 LEU LEU I . n 
B 1 142 VAL 142 142 142 VAL VAL I . n 
B 1 143 LYS 143 143 143 LYS LYS I . n 
B 1 144 ASP 144 144 144 ASP ASP I . n 
B 1 145 TYR 145 145 145 TYR TYR I . n 
B 1 146 PHE 146 146 146 PHE PHE I . n 
B 1 147 PRO 147 147 147 PRO PRO I . n 
B 1 148 GLU 148 148 148 GLU GLU I . n 
B 1 149 PRO 149 149 149 PRO PRO I . n 
B 1 150 VAL 150 150 150 VAL VAL I . n 
B 1 151 THR 151 151 151 THR THR I . n 
B 1 152 VAL 152 152 152 VAL VAL I . n 
B 1 153 SER 153 153 153 SER SER I . n 
B 1 154 TRP 154 154 154 TRP TRP I . n 
B 1 155 ASN 155 155 155 ASN ASN I . n 
B 1 156 SER 156 156 156 SER SER I . n 
B 1 157 GLY 157 157 157 GLY GLY I . n 
B 1 158 ALA 158 158 158 ALA ALA I . n 
B 1 159 LEU 159 159 159 LEU LEU I . n 
B 1 160 THR 160 160 160 THR THR I . n 
B 1 161 SER 161 161 161 SER SER I . n 
B 1 162 GLY 162 162 162 GLY GLY I . n 
B 1 163 VAL 163 163 163 VAL VAL I . n 
B 1 164 HIS 164 164 164 HIS HIS I . n 
B 1 165 THR 165 165 165 THR THR I . n 
B 1 166 PHE 166 166 166 PHE PHE I . n 
B 1 167 PRO 167 167 167 PRO PRO I . n 
B 1 168 ALA 168 168 168 ALA ALA I . n 
B 1 169 VAL 169 169 169 VAL VAL I . n 
B 1 170 LEU 170 170 170 LEU LEU I . n 
B 1 171 GLN 171 171 171 GLN GLN I . n 
B 1 172 SER 172 172 172 SER SER I . n 
B 1 173 SER 173 173 173 SER SER I . n 
B 1 174 GLY 174 174 174 GLY GLY I . n 
B 1 175 LEU 175 175 175 LEU LEU I . n 
B 1 176 TYR 176 176 176 TYR TYR I . n 
B 1 177 SER 177 177 177 SER SER I . n 
B 1 178 LEU 178 178 178 LEU LEU I . n 
B 1 179 SER 179 179 179 SER SER I . n 
B 1 180 SER 180 180 180 SER SER I . n 
B 1 181 VAL 181 181 181 VAL VAL I . n 
B 1 182 VAL 182 182 182 VAL VAL I . n 
B 1 183 THR 183 183 183 THR THR I . n 
B 1 184 VAL 184 184 184 VAL VAL I . n 
B 1 185 PRO 185 185 185 PRO PRO I . n 
B 1 186 SER 186 186 186 SER SER I . n 
B 1 187 SER 187 187 187 SER SER I . n 
B 1 188 SER 188 188 188 SER SER I . n 
B 1 189 LEU 189 189 189 LEU LEU I . n 
B 1 190 GLY 190 190 190 GLY GLY I . n 
B 1 191 THR 191 191 191 THR THR I . n 
B 1 192 GLN 192 192 192 GLN GLN I . n 
B 1 193 THR 193 193 193 THR THR I . n 
B 1 194 TYR 194 194 194 TYR TYR I . n 
B 1 195 ILE 195 195 195 ILE ILE I . n 
B 1 196 CYS 196 196 196 CYS CYS I . n 
B 1 197 ASN 197 197 197 ASN ASN I . n 
B 1 198 VAL 198 198 198 VAL VAL I . n 
B 1 199 ASN 199 199 199 ASN ASN I . n 
B 1 200 HIS 200 200 200 HIS HIS I . n 
B 1 201 LYS 201 201 201 LYS LYS I . n 
B 1 202 PRO 202 202 202 PRO PRO I . n 
B 1 203 SER 203 203 203 SER SER I . n 
B 1 204 ASN 204 204 204 ASN ASN I . n 
B 1 205 THR 205 205 205 THR THR I . n 
B 1 206 LYS 206 206 206 LYS LYS I . n 
B 1 207 VAL 207 207 207 VAL VAL I . n 
B 1 208 ASP 208 208 208 ASP ASP I . n 
B 1 209 LYS 209 209 209 LYS LYS I . n 
B 1 210 ARG 210 210 210 ARG ARG I . n 
B 1 211 VAL 211 211 211 VAL VAL I . n 
B 1 212 GLU 212 212 212 GLU GLU I . n 
B 1 213 PRO 213 213 213 PRO PRO I . n 
B 1 214 LYS 214 214 214 LYS LYS I . n 
B 1 215 SER 215 215 215 SER SER I . n 
B 1 216 CYS 216 216 216 CYS CYS I . n 
C 2 1   UNK 1   3   3   UNK UNK K . n 
C 2 2   VAL 2   4   4   VAL VAL K . n 
C 2 3   GLN 3   5   5   GLN GLN K . n 
C 2 4   LEU 4   6   6   LEU LEU K . n 
C 2 5   UNK 5   7   7   UNK UNK K . n 
C 2 6   UNK 6   8   8   UNK UNK K . n 
C 2 7   SER 7   9   9   SER SER K . n 
C 2 8   GLY 8   10  10  GLY GLY K . n 
C 2 9   GLY 9   11  11  GLY GLY K . n 
C 2 10  GLY 10  12  12  GLY GLY K . n 
C 2 11  UNK 11  13  13  UNK UNK K . n 
C 2 12  VAL 12  14  14  VAL VAL K . n 
C 2 13  GLN 13  15  15  GLN GLN K . n 
C 2 14  UNK 14  16  16  UNK UNK K . n 
C 2 15  GLY 15  17  17  GLY GLY K . n 
C 2 16  UNK 16  18  18  UNK UNK K . n 
C 2 17  SER 17  19  19  SER SER K . n 
C 2 18  LEU 18  20  20  LEU LEU K . n 
C 2 19  UNK 19  21  21  UNK UNK K . n 
C 2 20  LEU 20  22  22  LEU LEU K . n 
C 2 21  SER 21  23  23  SER SER K . n 
C 2 22  CYS 22  24  24  CYS CYS K . n 
C 2 23  UNK 23  25  25  UNK UNK K . n 
C 2 24  ALA 24  26  26  ALA ALA K . n 
C 2 25  UNK 25  27  27  UNK ALA K . n 
C 2 26  UNK 26  28  28  UNK UNK K . n 
C 2 27  UNK 27  29  29  UNK UNK K . n 
C 2 28  UNK 28  30  30  UNK UNK K . n 
C 2 29  UNK 29  31  31  UNK UNK K . n 
C 2 30  UNK 30  32  32  UNK UNK K . n 
C 2 31  UNK 31  33  33  UNK UNK K . n 
C 2 32  UNK 32  34  34  UNK UNK K . n 
C 2 33  UNK 33  35  35  UNK UNK K . n 
C 2 34  UNK 34  36  36  UNK UNK K . n 
C 2 35  UNK 35  37  37  UNK UNK K . n 
C 2 36  TRP 36  38  38  TRP TRP K . n 
C 2 37  UNK 37  39  39  UNK UNK K . n 
C 2 38  ARG 38  40  40  ARG ARG K . n 
C 2 39  GLN 39  41  41  GLN GLN K . n 
C 2 40  UNK 40  42  42  UNK UNK K . n 
C 2 41  PRO 41  43  43  PRO PRO K . n 
C 2 42  GLY 42  44  44  GLY GLY K . n 
C 2 43  UNK 43  45  45  UNK UNK K . n 
C 2 44  UNK 44  46  46  UNK UNK K . n 
C 2 45  ARG 45  47  47  ARG ARG K . n 
C 2 46  GLU 46  48  48  GLU GLU K . n 
C 2 47  UNK 47  49  49  UNK UNK K . n 
C 2 48  VAL 48  50  50  VAL VAL K . n 
C 2 49  UNK 49  51  51  UNK UNK K . n 
C 2 50  UNK 50  52  52  UNK UNK K . n 
C 2 51  UNK 51  53  53  UNK UNK K . n 
C 2 52  UNK 52  54  54  UNK UNK K . n 
C 2 53  UNK 53  55  55  UNK UNK K . n 
C 2 54  UNK 54  56  56  UNK UNK K . n 
C 2 55  UNK 55  57  57  UNK UNK K . n 
C 2 56  UNK 56  58  58  UNK UNK K . n 
C 2 57  UNK 57  59  59  UNK UNK K . n 
C 2 58  UNK 58  60  60  UNK UNK K . n 
C 2 59  UNK 59  61  61  UNK UNK K . n 
C 2 60  UNK 60  62  62  UNK UNK K . n 
C 2 61  UNK 61  63  63  UNK UNK K . n 
C 2 62  ASP 62  64  64  ASP ASP K . n 
C 2 63  SER 63  65  65  SER SER K . n 
C 2 64  UNK 64  66  66  UNK UNK K . n 
C 2 65  UNK 65  67  67  UNK UNK K . n 
C 2 66  GLY 66  68  68  GLY GLY K . n 
C 2 67  ARG 67  69  69  ARG ARG K . n 
C 2 68  PHE 68  70  70  PHE PHE K . n 
C 2 69  THR 69  71  71  THR THR K . n 
C 2 70  UNK 70  72  72  UNK UNK K . n 
C 2 71  SER 71  73  73  SER SER K . n 
C 2 72  UNK 72  74  74  UNK UNK K . n 
C 2 73  ASP 73  75  75  ASP ASP K . n 
C 2 74  UNK 74  76  76  UNK UNK K . n 
C 2 75  UNK 75  77  77  UNK UNK K . n 
C 2 76  UNK 76  78  78  UNK UNK K . n 
C 2 77  UNK 77  79  79  UNK UNK K . n 
C 2 78  UNK 78  80  80  UNK UNK K . n 
C 2 79  UNK 79  81  81  UNK UNK K . n 
C 2 80  UNK 80  82  82  UNK UNK K . n 
C 2 81  LEU 81  83  83  LEU LEU K . n 
C 2 82  GLN 82  84  84  GLN GLN K . n 
C 2 83  UNK 83  85  85  UNK UNK K . n 
C 2 84  UNK 84  86  86  UNK UNK K . n 
C 2 85  UNK 85  87  87  UNK ALA K . n 
C 2 86  LEU 86  88  88  LEU LEU K . n 
C 2 87  UNK 87  89  89  UNK UNK K . n 
C 2 88  UNK 88  90  90  UNK UNK K . n 
C 2 89  UNK 89  91  91  UNK UNK K . n 
C 2 90  ASP 90  92  92  ASP ASP K . n 
C 2 91  UNK 91  93  93  UNK UNK K . n 
C 2 92  ALA 92  94  94  ALA ALA K . n 
C 2 93  UNK 93  95  95  UNK UNK K . n 
C 2 94  TYR 94  96  96  TYR TYR K . n 
C 2 95  TYR 95  97  97  TYR TYR K . n 
C 2 96  CYS 96  98  98  CYS CYS K . n 
C 2 97  UNK 97  99  99  UNK UNK K . n 
C 2 98  UNK 98  100 100 UNK UNK K . n 
C 2 99  UNK 99  101 101 UNK UNK K . n 
C 2 100 UNK 100 102 102 UNK UNK K . n 
C 2 101 UNK 101 103 103 UNK UNK K . n 
C 2 102 UNK 102 104 104 UNK UNK K . n 
C 2 103 UNK 103 105 105 UNK UNK K . n 
C 2 104 UNK 104 106 106 UNK ALA K . n 
C 2 105 UNK 105 107 107 UNK UNK K . n 
C 2 106 UNK 106 108 108 UNK UNK K . n 
C 2 107 UNK 107 109 109 UNK UNK K . n 
C 2 108 UNK 108 110 110 UNK UNK K . n 
C 2 109 UNK 109 111 111 UNK UNK K . n 
C 2 110 UNK 110 112 112 UNK UNK K . n 
C 2 111 TRP 111 113 113 TRP TRP K . n 
C 2 112 GLY 112 114 114 GLY GLY K . n 
C 2 113 UNK 113 115 115 UNK UNK K . n 
C 2 114 GLY 114 116 116 GLY GLY K . n 
C 2 115 THR 115 117 117 THR THR K . n 
C 2 116 UNK 116 118 118 UNK UNK K . n 
C 2 117 VAL 117 119 119 VAL VAL K . n 
C 2 118 THR 118 120 120 THR THR K . n 
C 2 119 VAL 119 121 121 VAL VAL K . n 
C 2 120 SER 120 122 122 SER SER K . n 
C 2 121 SER 121 123 ?   ?   ?   K . n 
C 2 122 HIS 122 124 ?   ?   ?   K . n 
C 2 123 HIS 123 125 ?   ?   ?   K . n 
C 2 124 HIS 124 126 ?   ?   ?   K . n 
C 2 125 HIS 125 127 ?   ?   ?   K . n 
C 2 126 HIS 126 128 ?   ?   ?   K . n 
C 2 127 HIS 127 129 ?   ?   ?   K . n 
D 3 1   ASP 1   1   1   ASP ASP L . n 
D 3 2   ILE 2   2   2   ILE ILE L . n 
D 3 3   VAL 3   3   3   VAL VAL L . n 
D 3 4   LEU 4   4   4   LEU LEU L . n 
D 3 5   THR 5   5   5   THR THR L . n 
D 3 6   GLN 6   6   6   GLN GLN L . n 
D 3 7   THR 7   7   7   THR THR L . n 
D 3 8   PRO 8   8   8   PRO PRO L . n 
D 3 9   ALA 9   9   9   ALA ALA L . n 
D 3 10  ILE 10  10  10  ILE ILE L . n 
D 3 11  MET 11  11  11  MET MET L . n 
D 3 12  SER 12  12  12  SER SER L . n 
D 3 13  ALA 13  13  13  ALA ALA L . n 
D 3 14  SER 14  14  14  SER SER L . n 
D 3 15  PRO 15  15  15  PRO PRO L . n 
D 3 16  GLY 16  16  16  GLY GLY L . n 
D 3 17  GLU 17  17  17  GLU GLU L . n 
D 3 18  LYS 18  18  18  LYS LYS L . n 
D 3 19  VAL 19  19  19  VAL VAL L . n 
D 3 20  THR 20  20  20  THR THR L . n 
D 3 21  LEU 21  21  21  LEU LEU L . n 
D 3 22  THR 22  22  22  THR THR L . n 
D 3 23  CYS 23  23  23  CYS CYS L . n 
D 3 24  SER 24  24  24  SER SER L . n 
D 3 25  ALA 25  25  25  ALA ALA L . n 
D 3 26  SER 26  26  26  SER SER L . n 
D 3 27  SER 27  27  27  SER SER L . n 
D 3 28  SER 28  29  29  SER SER L . n 
D 3 29  VAL 29  30  30  VAL VAL L . n 
D 3 30  SER 30  31  31  SER SER L . n 
D 3 31  TYR 31  32  32  TYR TYR L . n 
D 3 32  MET 32  33  33  MET MET L . n 
D 3 33  HIS 33  34  34  HIS HIS L . n 
D 3 34  TRP 34  35  35  TRP TRP L . n 
D 3 35  PHE 35  36  36  PHE PHE L . n 
D 3 36  GLN 36  37  37  GLN GLN L . n 
D 3 37  GLN 37  38  38  GLN GLN L . n 
D 3 38  LYS 38  39  39  LYS LYS L . n 
D 3 39  SER 39  40  40  SER SER L . n 
D 3 40  GLY 40  41  41  GLY GLY L . n 
D 3 41  THR 41  42  42  THR THR L . n 
D 3 42  SER 42  43  43  SER SER L . n 
D 3 43  PRO 43  44  44  PRO PRO L . n 
D 3 44  LYS 44  45  45  LYS LYS L . n 
D 3 45  ARG 45  46  46  ARG ARG L . n 
D 3 46  TRP 46  47  47  TRP TRP L . n 
D 3 47  ILE 47  48  48  ILE ILE L . n 
D 3 48  TYR 48  49  49  TYR TYR L . n 
D 3 49  ASP 49  50  50  ASP ASP L . n 
D 3 50  THR 50  51  51  THR THR L . n 
D 3 51  SER 51  52  52  SER SER L . n 
D 3 52  LYS 52  53  53  LYS LYS L . n 
D 3 53  LEU 53  54  54  LEU LEU L . n 
D 3 54  ALA 54  55  55  ALA ALA L . n 
D 3 55  SER 55  56  56  SER SER L . n 
D 3 56  GLY 56  57  57  GLY GLY L . n 
D 3 57  VAL 57  58  58  VAL VAL L . n 
D 3 58  PRO 58  59  59  PRO PRO L . n 
D 3 59  ALA 59  60  60  ALA ALA L . n 
D 3 60  ARG 60  61  61  ARG ARG L . n 
D 3 61  PHE 61  62  62  PHE PHE L . n 
D 3 62  SER 62  63  63  SER SER L . n 
D 3 63  GLY 63  64  64  GLY GLY L . n 
D 3 64  SER 64  65  65  SER SER L . n 
D 3 65  GLY 65  66  66  GLY GLY L . n 
D 3 66  SER 66  67  67  SER SER L . n 
D 3 67  GLY 67  68  68  GLY GLY L . n 
D 3 68  THR 68  69  69  THR THR L . n 
D 3 69  SER 69  70  70  SER SER L . n 
D 3 70  TYR 70  71  71  TYR TYR L . n 
D 3 71  SER 71  72  72  SER SER L . n 
D 3 72  LEU 72  73  73  LEU LEU L . n 
D 3 73  THR 73  74  74  THR THR L . n 
D 3 74  ILE 74  75  75  ILE ILE L . n 
D 3 75  SER 75  76  76  SER SER L . n 
D 3 76  SER 76  77  77  SER SER L . n 
D 3 77  MET 77  78  78  MET MET L . n 
D 3 78  GLU 78  79  79  GLU GLU L . n 
D 3 79  ALA 79  80  80  ALA ALA L . n 
D 3 80  GLU 80  81  81  GLU GLU L . n 
D 3 81  ASP 81  82  82  ASP ASP L . n 
D 3 82  ALA 82  83  83  ALA ALA L . n 
D 3 83  ALA 83  84  84  ALA ALA L . n 
D 3 84  ALA 84  85  85  ALA ALA L . n 
D 3 85  TYR 85  86  86  TYR TYR L . n 
D 3 86  TYR 86  87  87  TYR TYR L . n 
D 3 87  CYS 87  88  88  CYS CYS L . n 
D 3 88  GLN 88  89  89  GLN GLN L . n 
D 3 89  GLN 89  90  90  GLN GLN L . n 
D 3 90  TRP 90  91  91  TRP TRP L . n 
D 3 91  SER 91  92  92  SER SER L . n 
D 3 92  SER 92  93  93  SER SER L . n 
D 3 93  ASP 93  94  94  ASP ASP L . n 
D 3 94  PRO 94  95  95  PRO PRO L . n 
D 3 95  PRO 95  95  95  PRO PRO L A n 
D 3 96  MET 96  95  95  MET MET L B n 
D 3 97  LEU 97  96  96  LEU LEU L . n 
D 3 98  THR 98  97  97  THR THR L . n 
D 3 99  PHE 99  98  98  PHE PHE L . n 
D 3 100 GLY 100 99  99  GLY GLY L . n 
D 3 101 ALA 101 100 100 ALA ALA L . n 
D 3 102 GLY 102 101 101 GLY GLY L . n 
D 3 103 THR 103 102 102 THR THR L . n 
D 3 104 LYS 104 103 103 LYS LYS L . n 
D 3 105 LEU 105 104 104 LEU LEU L . n 
D 3 106 GLU 106 105 105 GLU GLU L . n 
D 3 107 LEU 107 106 106 LEU LEU L . n 
D 3 108 LYS 108 107 107 LYS LYS L . n 
D 3 109 ARG 109 108 108 ARG ARG L . n 
D 3 110 THR 110 109 109 THR THR L . n 
D 3 111 VAL 111 110 110 VAL VAL L . n 
D 3 112 ALA 112 111 111 ALA ALA L . n 
D 3 113 ALA 113 112 112 ALA ALA L . n 
D 3 114 PRO 114 113 113 PRO PRO L . n 
D 3 115 SER 115 114 114 SER SER L . n 
D 3 116 VAL 116 115 115 VAL VAL L . n 
D 3 117 PHE 117 116 116 PHE PHE L . n 
D 3 118 ILE 118 117 117 ILE ILE L . n 
D 3 119 PHE 119 118 118 PHE PHE L . n 
D 3 120 PRO 120 119 119 PRO PRO L . n 
D 3 121 PRO 121 120 120 PRO PRO L . n 
D 3 122 SER 122 121 121 SER SER L . n 
D 3 123 ASP 123 122 122 ASP ASP L . n 
D 3 124 GLU 124 123 123 GLU GLU L . n 
D 3 125 GLN 125 124 124 GLN GLN L . n 
D 3 126 LEU 126 125 125 LEU LEU L . n 
D 3 127 LYS 127 126 126 LYS LYS L . n 
D 3 128 SER 128 127 127 SER SER L . n 
D 3 129 GLY 129 128 128 GLY GLY L . n 
D 3 130 THR 130 129 129 THR THR L . n 
D 3 131 ALA 131 130 130 ALA ALA L . n 
D 3 132 SER 132 131 131 SER SER L . n 
D 3 133 VAL 133 132 132 VAL VAL L . n 
D 3 134 VAL 134 133 133 VAL VAL L . n 
D 3 135 CYS 135 134 134 CYS CYS L . n 
D 3 136 LEU 136 135 135 LEU LEU L . n 
D 3 137 LEU 137 136 136 LEU LEU L . n 
D 3 138 ASN 138 137 137 ASN ASN L . n 
D 3 139 ASN 139 138 138 ASN ASN L . n 
D 3 140 PHE 140 139 139 PHE PHE L . n 
D 3 141 TYR 141 140 140 TYR TYR L . n 
D 3 142 PRO 142 141 141 PRO PRO L . n 
D 3 143 ARG 143 142 142 ARG ARG L . n 
D 3 144 GLU 144 143 143 GLU GLU L . n 
D 3 145 ALA 145 144 144 ALA ALA L . n 
D 3 146 LYS 146 145 145 LYS LYS L . n 
D 3 147 VAL 147 146 146 VAL VAL L . n 
D 3 148 GLN 148 147 147 GLN GLN L . n 
D 3 149 TRP 149 148 148 TRP TRP L . n 
D 3 150 LYS 150 149 149 LYS LYS L . n 
D 3 151 VAL 151 150 150 VAL VAL L . n 
D 3 152 ASP 152 151 151 ASP ASP L . n 
D 3 153 ASN 153 152 152 ASN ASN L . n 
D 3 154 ALA 154 153 153 ALA ALA L . n 
D 3 155 LEU 155 154 154 LEU LEU L . n 
D 3 156 GLN 156 155 155 GLN GLN L . n 
D 3 157 SER 157 156 156 SER SER L . n 
D 3 158 GLY 158 157 157 GLY GLY L . n 
D 3 159 ASN 159 158 158 ASN ASN L . n 
D 3 160 SER 160 159 159 SER SER L . n 
D 3 161 GLN 161 160 160 GLN GLN L . n 
D 3 162 GLU 162 161 161 GLU GLU L . n 
D 3 163 SER 163 162 162 SER SER L . n 
D 3 164 VAL 164 163 163 VAL VAL L . n 
D 3 165 THR 165 164 164 THR THR L . n 
D 3 166 GLU 166 165 165 GLU GLU L . n 
D 3 167 GLN 167 166 166 GLN GLN L . n 
D 3 168 ASP 168 167 167 ASP ASP L . n 
D 3 169 SER 169 168 168 SER SER L . n 
D 3 170 LYS 170 169 169 LYS LYS L . n 
D 3 171 ASP 171 170 170 ASP ASP L . n 
D 3 172 SER 172 171 171 SER SER L . n 
D 3 173 THR 173 172 172 THR THR L . n 
D 3 174 TYR 174 173 173 TYR TYR L . n 
D 3 175 SER 175 174 174 SER SER L . n 
D 3 176 LEU 176 175 175 LEU LEU L . n 
D 3 177 SER 177 176 176 SER SER L . n 
D 3 178 SER 178 177 177 SER SER L . n 
D 3 179 THR 179 178 178 THR THR L . n 
D 3 180 LEU 180 179 179 LEU LEU L . n 
D 3 181 THR 181 180 180 THR THR L . n 
D 3 182 LEU 182 181 181 LEU LEU L . n 
D 3 183 SER 183 182 182 SER SER L . n 
D 3 184 LYS 184 183 183 LYS LYS L . n 
D 3 185 ALA 185 184 184 ALA ALA L . n 
D 3 186 ASP 186 185 185 ASP ASP L . n 
D 3 187 TYR 187 186 186 TYR TYR L . n 
D 3 188 GLU 188 187 187 GLU GLU L . n 
D 3 189 LYS 189 188 188 LYS LYS L . n 
D 3 190 HIS 190 189 189 HIS HIS L . n 
D 3 191 LYS 191 190 190 LYS LYS L . n 
D 3 192 VAL 192 191 191 VAL VAL L . n 
D 3 193 TYR 193 192 192 TYR TYR L . n 
D 3 194 ALA 194 193 193 ALA ALA L . n 
D 3 195 CYS 195 194 194 CYS CYS L . n 
D 3 196 GLU 196 195 195 GLU GLU L . n 
D 3 197 VAL 197 196 196 VAL VAL L . n 
D 3 198 THR 198 197 197 THR THR L . n 
D 3 199 HIS 199 198 198 HIS HIS L . n 
D 3 200 GLN 200 199 199 GLN GLN L . n 
D 3 201 GLY 201 200 200 GLY GLY L . n 
D 3 202 LEU 202 201 201 LEU LEU L . n 
D 3 203 SER 203 202 202 SER SER L . n 
D 3 204 SER 204 203 203 SER SER L . n 
D 3 205 PRO 205 204 204 PRO PRO L . n 
D 3 206 VAL 206 205 205 VAL VAL L . n 
D 3 207 THR 207 206 206 THR THR L . n 
D 3 208 LYS 208 207 207 LYS LYS L . n 
D 3 209 SER 209 208 208 SER SER L . n 
D 3 210 PHE 210 209 209 PHE PHE L . n 
D 3 211 ASN 211 210 210 ASN ASN L . n 
D 3 212 ARG 212 211 211 ARG ARG L . n 
D 3 213 GLY 213 212 212 GLY GLY L . n 
D 3 214 GLU 214 213 213 GLU GLU L . n 
D 3 215 CYS 215 214 ?   ?   ?   L . n 
E 3 1   ASP 1   1   ?   ?   ?   M . n 
E 3 2   ILE 2   2   ?   ?   ?   M . n 
E 3 3   VAL 3   3   ?   ?   ?   M . n 
E 3 4   LEU 4   4   4   LEU LEU M . n 
E 3 5   THR 5   5   5   THR THR M . n 
E 3 6   GLN 6   6   6   GLN GLN M . n 
E 3 7   THR 7   7   7   THR THR M . n 
E 3 8   PRO 8   8   8   PRO PRO M . n 
E 3 9   ALA 9   9   9   ALA ALA M . n 
E 3 10  ILE 10  10  10  ILE ILE M . n 
E 3 11  MET 11  11  11  MET MET M . n 
E 3 12  SER 12  12  12  SER SER M . n 
E 3 13  ALA 13  13  13  ALA ALA M . n 
E 3 14  SER 14  14  14  SER SER M . n 
E 3 15  PRO 15  15  15  PRO PRO M . n 
E 3 16  GLY 16  16  16  GLY GLY M . n 
E 3 17  GLU 17  17  17  GLU GLU M . n 
E 3 18  LYS 18  18  18  LYS LYS M . n 
E 3 19  VAL 19  19  19  VAL VAL M . n 
E 3 20  THR 20  20  20  THR THR M . n 
E 3 21  LEU 21  21  21  LEU LEU M . n 
E 3 22  THR 22  22  22  THR THR M . n 
E 3 23  CYS 23  23  23  CYS CYS M . n 
E 3 24  SER 24  24  24  SER SER M . n 
E 3 25  ALA 25  25  25  ALA ALA M . n 
E 3 26  SER 26  27  ?   ?   ?   M . n 
E 3 27  SER 27  28  ?   ?   ?   M . n 
E 3 28  SER 28  29  ?   ?   ?   M . n 
E 3 29  VAL 29  30  ?   ?   ?   M . n 
E 3 30  SER 30  31  ?   ?   ?   M . n 
E 3 31  TYR 31  32  ?   ?   ?   M . n 
E 3 32  MET 32  33  33  MET MET M . n 
E 3 33  HIS 33  34  34  HIS HIS M . n 
E 3 34  TRP 34  35  35  TRP TRP M . n 
E 3 35  PHE 35  36  36  PHE PHE M . n 
E 3 36  GLN 36  37  37  GLN GLN M . n 
E 3 37  GLN 37  38  38  GLN GLN M . n 
E 3 38  LYS 38  39  39  LYS LYS M . n 
E 3 39  SER 39  40  40  SER SER M . n 
E 3 40  GLY 40  41  41  GLY GLY M . n 
E 3 41  THR 41  42  42  THR THR M . n 
E 3 42  SER 42  43  43  SER SER M . n 
E 3 43  PRO 43  44  44  PRO PRO M . n 
E 3 44  LYS 44  45  45  LYS LYS M . n 
E 3 45  ARG 45  46  46  ARG ARG M . n 
E 3 46  TRP 46  47  47  TRP TRP M . n 
E 3 47  ILE 47  48  48  ILE ILE M . n 
E 3 48  TYR 48  49  49  TYR TYR M . n 
E 3 49  ASP 49  50  50  ASP ASP M . n 
E 3 50  THR 50  51  51  THR THR M . n 
E 3 51  SER 51  52  52  SER SER M . n 
E 3 52  LYS 52  53  53  LYS LYS M . n 
E 3 53  LEU 53  54  54  LEU LEU M . n 
E 3 54  ALA 54  55  55  ALA ALA M . n 
E 3 55  SER 55  56  56  SER SER M . n 
E 3 56  GLY 56  57  57  GLY GLY M . n 
E 3 57  VAL 57  58  58  VAL VAL M . n 
E 3 58  PRO 58  59  59  PRO PRO M . n 
E 3 59  ALA 59  60  60  ALA ALA M . n 
E 3 60  ARG 60  61  61  ARG ARG M . n 
E 3 61  PHE 61  62  62  PHE PHE M . n 
E 3 62  SER 62  63  63  SER SER M . n 
E 3 63  GLY 63  64  64  GLY GLY M . n 
E 3 64  SER 64  65  65  SER SER M . n 
E 3 65  GLY 65  66  66  GLY GLY M . n 
E 3 66  SER 66  67  67  SER SER M . n 
E 3 67  GLY 67  68  68  GLY GLY M . n 
E 3 68  THR 68  69  69  THR THR M . n 
E 3 69  SER 69  70  70  SER SER M . n 
E 3 70  TYR 70  71  71  TYR TYR M . n 
E 3 71  SER 71  72  72  SER SER M . n 
E 3 72  LEU 72  73  73  LEU LEU M . n 
E 3 73  THR 73  74  74  THR THR M . n 
E 3 74  ILE 74  75  75  ILE ILE M . n 
E 3 75  SER 75  76  76  SER SER M . n 
E 3 76  SER 76  77  77  SER SER M . n 
E 3 77  MET 77  78  78  MET MET M . n 
E 3 78  GLU 78  79  79  GLU GLU M . n 
E 3 79  ALA 79  80  80  ALA ALA M . n 
E 3 80  GLU 80  81  81  GLU GLU M . n 
E 3 81  ASP 81  82  82  ASP ASP M . n 
E 3 82  ALA 82  83  83  ALA ALA M . n 
E 3 83  ALA 83  84  84  ALA ALA M . n 
E 3 84  ALA 84  85  85  ALA ALA M . n 
E 3 85  TYR 85  86  86  TYR TYR M . n 
E 3 86  TYR 86  87  87  TYR TYR M . n 
E 3 87  CYS 87  88  88  CYS CYS M . n 
E 3 88  GLN 88  89  89  GLN GLN M . n 
E 3 89  GLN 89  90  90  GLN GLN M . n 
E 3 90  TRP 90  91  91  TRP TRP M . n 
E 3 91  SER 91  92  92  SER SER M . n 
E 3 92  SER 92  93  93  SER SER M . n 
E 3 93  ASP 93  94  ?   ?   ?   M . n 
E 3 94  PRO 94  95  95  PRO PRO M . n 
E 3 95  PRO 95  95  95  PRO PRO M A n 
E 3 96  MET 96  95  95  MET MET M B n 
E 3 97  LEU 97  96  96  LEU LEU M . n 
E 3 98  THR 98  97  97  THR THR M . n 
E 3 99  PHE 99  98  98  PHE PHE M . n 
E 3 100 GLY 100 99  99  GLY GLY M . n 
E 3 101 ALA 101 100 100 ALA ALA M . n 
E 3 102 GLY 102 101 101 GLY GLY M . n 
E 3 103 THR 103 102 102 THR THR M . n 
E 3 104 LYS 104 103 103 LYS LYS M . n 
E 3 105 LEU 105 104 104 LEU LEU M . n 
E 3 106 GLU 106 105 105 GLU GLU M . n 
E 3 107 LEU 107 106 106 LEU LEU M . n 
E 3 108 LYS 108 107 107 LYS LYS M . n 
E 3 109 ARG 109 108 108 ARG ARG M . n 
E 3 110 THR 110 109 109 THR THR M . n 
E 3 111 VAL 111 110 110 VAL VAL M . n 
E 3 112 ALA 112 111 111 ALA ALA M . n 
E 3 113 ALA 113 112 112 ALA ALA M . n 
E 3 114 PRO 114 113 113 PRO PRO M . n 
E 3 115 SER 115 114 114 SER SER M . n 
E 3 116 VAL 116 115 115 VAL VAL M . n 
E 3 117 PHE 117 116 116 PHE PHE M . n 
E 3 118 ILE 118 117 117 ILE ILE M . n 
E 3 119 PHE 119 118 118 PHE PHE M . n 
E 3 120 PRO 120 119 119 PRO PRO M . n 
E 3 121 PRO 121 120 120 PRO PRO M . n 
E 3 122 SER 122 121 121 SER SER M . n 
E 3 123 ASP 123 122 122 ASP ASP M . n 
E 3 124 GLU 124 123 123 GLU GLU M . n 
E 3 125 GLN 125 124 124 GLN GLN M . n 
E 3 126 LEU 126 125 125 LEU LEU M . n 
E 3 127 LYS 127 126 126 LYS LYS M . n 
E 3 128 SER 128 127 127 SER SER M . n 
E 3 129 GLY 129 128 128 GLY GLY M . n 
E 3 130 THR 130 129 129 THR THR M . n 
E 3 131 ALA 131 130 130 ALA ALA M . n 
E 3 132 SER 132 131 131 SER SER M . n 
E 3 133 VAL 133 132 132 VAL VAL M . n 
E 3 134 VAL 134 133 133 VAL VAL M . n 
E 3 135 CYS 135 134 134 CYS CYS M . n 
E 3 136 LEU 136 135 135 LEU LEU M . n 
E 3 137 LEU 137 136 136 LEU LEU M . n 
E 3 138 ASN 138 137 137 ASN ASN M . n 
E 3 139 ASN 139 138 138 ASN ASN M . n 
E 3 140 PHE 140 139 139 PHE PHE M . n 
E 3 141 TYR 141 140 140 TYR TYR M . n 
E 3 142 PRO 142 141 141 PRO PRO M . n 
E 3 143 ARG 143 142 142 ARG ARG M . n 
E 3 144 GLU 144 143 143 GLU GLU M . n 
E 3 145 ALA 145 144 144 ALA ALA M . n 
E 3 146 LYS 146 145 145 LYS LYS M . n 
E 3 147 VAL 147 146 146 VAL VAL M . n 
E 3 148 GLN 148 147 147 GLN GLN M . n 
E 3 149 TRP 149 148 148 TRP TRP M . n 
E 3 150 LYS 150 149 149 LYS LYS M . n 
E 3 151 VAL 151 150 150 VAL VAL M . n 
E 3 152 ASP 152 151 151 ASP ASP M . n 
E 3 153 ASN 153 152 152 ASN ASN M . n 
E 3 154 ALA 154 153 153 ALA ALA M . n 
E 3 155 LEU 155 154 154 LEU LEU M . n 
E 3 156 GLN 156 155 155 GLN GLN M . n 
E 3 157 SER 157 156 156 SER SER M . n 
E 3 158 GLY 158 157 157 GLY GLY M . n 
E 3 159 ASN 159 158 158 ASN ASN M . n 
E 3 160 SER 160 159 159 SER SER M . n 
E 3 161 GLN 161 160 160 GLN GLN M . n 
E 3 162 GLU 162 161 161 GLU GLU M . n 
E 3 163 SER 163 162 162 SER SER M . n 
E 3 164 VAL 164 163 163 VAL VAL M . n 
E 3 165 THR 165 164 164 THR THR M . n 
E 3 166 GLU 166 165 165 GLU GLU M . n 
E 3 167 GLN 167 166 166 GLN GLN M . n 
E 3 168 ASP 168 167 167 ASP ASP M . n 
E 3 169 SER 169 168 168 SER SER M . n 
E 3 170 LYS 170 169 169 LYS LYS M . n 
E 3 171 ASP 171 170 170 ASP ASP M . n 
E 3 172 SER 172 171 171 SER SER M . n 
E 3 173 THR 173 172 172 THR THR M . n 
E 3 174 TYR 174 173 173 TYR TYR M . n 
E 3 175 SER 175 174 174 SER SER M . n 
E 3 176 LEU 176 175 175 LEU LEU M . n 
E 3 177 SER 177 176 176 SER SER M . n 
E 3 178 SER 178 177 177 SER SER M . n 
E 3 179 THR 179 178 178 THR THR M . n 
E 3 180 LEU 180 179 179 LEU LEU M . n 
E 3 181 THR 181 180 180 THR THR M . n 
E 3 182 LEU 182 181 181 LEU LEU M . n 
E 3 183 SER 183 182 182 SER SER M . n 
E 3 184 LYS 184 183 183 LYS LYS M . n 
E 3 185 ALA 185 184 184 ALA ALA M . n 
E 3 186 ASP 186 185 185 ASP ASP M . n 
E 3 187 TYR 187 186 186 TYR TYR M . n 
E 3 188 GLU 188 187 187 GLU GLU M . n 
E 3 189 LYS 189 188 188 LYS LYS M . n 
E 3 190 HIS 190 189 189 HIS HIS M . n 
E 3 191 LYS 191 190 190 LYS LYS M . n 
E 3 192 VAL 192 191 191 VAL VAL M . n 
E 3 193 TYR 193 192 192 TYR TYR M . n 
E 3 194 ALA 194 193 193 ALA ALA M . n 
E 3 195 CYS 195 194 194 CYS CYS M . n 
E 3 196 GLU 196 195 195 GLU GLU M . n 
E 3 197 VAL 197 196 196 VAL VAL M . n 
E 3 198 THR 198 197 197 THR THR M . n 
E 3 199 HIS 199 198 198 HIS HIS M . n 
E 3 200 GLN 200 199 199 GLN GLN M . n 
E 3 201 GLY 201 200 200 GLY GLY M . n 
E 3 202 LEU 202 201 201 LEU LEU M . n 
E 3 203 SER 203 202 202 SER SER M . n 
E 3 204 SER 204 203 203 SER SER M . n 
E 3 205 PRO 205 204 204 PRO PRO M . n 
E 3 206 VAL 206 205 205 VAL VAL M . n 
E 3 207 THR 207 206 206 THR THR M . n 
E 3 208 LYS 208 207 207 LYS LYS M . n 
E 3 209 SER 209 208 208 SER SER M . n 
E 3 210 PHE 210 209 209 PHE PHE M . n 
E 3 211 ASN 211 210 210 ASN ASN M . n 
E 3 212 ARG 212 211 211 ARG ARG M . n 
E 3 213 GLY 213 212 212 GLY GLY M . n 
E 3 214 GLU 214 213 213 GLU GLU M . n 
E 3 215 CYS 215 214 ?   ?   ?   M . n 
F 2 1   UNK 1   3   3   UNK UNK V . n 
F 2 2   VAL 2   4   4   VAL VAL V . n 
F 2 3   GLN 3   5   5   GLN GLN V . n 
F 2 4   LEU 4   6   6   LEU LEU V . n 
F 2 5   UNK 5   7   7   UNK UNK V . n 
F 2 6   UNK 6   8   8   UNK UNK V . n 
F 2 7   SER 7   9   9   SER SER V . n 
F 2 8   GLY 8   10  10  GLY GLY V . n 
F 2 9   GLY 9   11  11  GLY GLY V . n 
F 2 10  GLY 10  12  12  GLY GLY V . n 
F 2 11  UNK 11  13  13  UNK UNK V . n 
F 2 12  VAL 12  14  14  VAL VAL V . n 
F 2 13  GLN 13  15  15  GLN GLN V . n 
F 2 14  UNK 14  16  16  UNK UNK V . n 
F 2 15  GLY 15  17  17  GLY GLY V . n 
F 2 16  UNK 16  18  18  UNK UNK V . n 
F 2 17  SER 17  19  19  SER SER V . n 
F 2 18  LEU 18  20  20  LEU LEU V . n 
F 2 19  UNK 19  21  21  UNK UNK V . n 
F 2 20  LEU 20  22  22  LEU LEU V . n 
F 2 21  SER 21  23  23  SER SER V . n 
F 2 22  CYS 22  24  24  CYS CYS V . n 
F 2 23  UNK 23  25  25  UNK UNK V . n 
F 2 24  ALA 24  26  26  ALA ALA V . n 
F 2 25  UNK 25  27  27  UNK UNK V . n 
F 2 26  UNK 26  28  28  UNK UNK V . n 
F 2 27  UNK 27  29  29  UNK UNK V . n 
F 2 28  UNK 28  30  30  UNK UNK V . n 
F 2 29  UNK 29  31  31  UNK UNK V . n 
F 2 30  UNK 30  32  32  UNK UNK V . n 
F 2 31  UNK 31  33  33  UNK UNK V . n 
F 2 32  UNK 32  34  34  UNK UNK V . n 
F 2 33  UNK 33  35  35  UNK UNK V . n 
F 2 34  UNK 34  36  36  UNK UNK V . n 
F 2 35  UNK 35  37  37  UNK UNK V . n 
F 2 36  TRP 36  38  38  TRP TRP V . n 
F 2 37  UNK 37  39  39  UNK UNK V . n 
F 2 38  ARG 38  40  40  ARG ARG V . n 
F 2 39  GLN 39  41  41  GLN GLN V . n 
F 2 40  UNK 40  42  42  UNK UNK V . n 
F 2 41  PRO 41  43  43  PRO PRO V . n 
F 2 42  GLY 42  44  44  GLY GLY V . n 
F 2 43  UNK 43  45  45  UNK UNK V . n 
F 2 44  UNK 44  46  46  UNK UNK V . n 
F 2 45  ARG 45  47  47  ARG ARG V . n 
F 2 46  GLU 46  48  48  GLU GLU V . n 
F 2 47  UNK 47  49  49  UNK UNK V . n 
F 2 48  VAL 48  50  50  VAL VAL V . n 
F 2 49  UNK 49  51  51  UNK UNK V . n 
F 2 50  UNK 50  52  52  UNK UNK V . n 
F 2 51  UNK 51  53  53  UNK UNK V . n 
F 2 52  UNK 52  54  54  UNK UNK V . n 
F 2 53  UNK 53  55  55  UNK UNK V . n 
F 2 54  UNK 54  56  56  UNK UNK V . n 
F 2 55  UNK 55  57  57  UNK UNK V . n 
F 2 56  UNK 56  58  58  UNK UNK V . n 
F 2 57  UNK 57  59  59  UNK UNK V . n 
F 2 58  UNK 58  60  60  UNK UNK V . n 
F 2 59  UNK 59  61  61  UNK UNK V . n 
F 2 60  UNK 60  62  62  UNK UNK V . n 
F 2 61  UNK 61  63  63  UNK UNK V . n 
F 2 62  ASP 62  64  64  ASP ASP V . n 
F 2 63  SER 63  65  65  SER SER V . n 
F 2 64  UNK 64  66  66  UNK UNK V . n 
F 2 65  UNK 65  67  67  UNK UNK V . n 
F 2 66  GLY 66  68  68  GLY GLY V . n 
F 2 67  ARG 67  69  69  ARG ARG V . n 
F 2 68  PHE 68  70  70  PHE PHE V . n 
F 2 69  THR 69  71  71  THR THR V . n 
F 2 70  UNK 70  72  72  UNK UNK V . n 
F 2 71  SER 71  73  73  SER SER V . n 
F 2 72  UNK 72  74  74  UNK UNK V . n 
F 2 73  ASP 73  75  75  ASP ASP V . n 
F 2 74  UNK 74  76  76  UNK UNK V . n 
F 2 75  UNK 75  77  77  UNK UNK V . n 
F 2 76  UNK 76  78  78  UNK UNK V . n 
F 2 77  UNK 77  79  79  UNK UNK V . n 
F 2 78  UNK 78  80  80  UNK UNK V . n 
F 2 79  UNK 79  81  81  UNK UNK V . n 
F 2 80  UNK 80  82  82  UNK UNK V . n 
F 2 81  LEU 81  83  83  LEU LEU V . n 
F 2 82  GLN 82  84  84  GLN GLN V . n 
F 2 83  UNK 83  85  85  UNK UNK V . n 
F 2 84  UNK 84  86  86  UNK UNK V . n 
F 2 85  UNK 85  87  87  UNK UNK V . n 
F 2 86  LEU 86  88  88  LEU LEU V . n 
F 2 87  UNK 87  89  89  UNK UNK V . n 
F 2 88  UNK 88  90  90  UNK UNK V . n 
F 2 89  UNK 89  91  91  UNK UNK V . n 
F 2 90  ASP 90  92  92  ASP ASP V . n 
F 2 91  UNK 91  93  93  UNK UNK V . n 
F 2 92  ALA 92  94  94  ALA ALA V . n 
F 2 93  UNK 93  95  95  UNK UNK V . n 
F 2 94  TYR 94  96  96  TYR TYR V . n 
F 2 95  TYR 95  97  97  TYR TYR V . n 
F 2 96  CYS 96  98  98  CYS CYS V . n 
F 2 97  UNK 97  99  99  UNK UNK V . n 
F 2 98  UNK 98  100 100 UNK UNK V . n 
F 2 99  UNK 99  101 101 UNK UNK V . n 
F 2 100 UNK 100 102 102 UNK UNK V . n 
F 2 101 UNK 101 103 103 UNK UNK V . n 
F 2 102 UNK 102 104 104 UNK UNK V . n 
F 2 103 UNK 103 105 105 UNK UNK V . n 
F 2 104 UNK 104 106 106 UNK UNK V . n 
F 2 105 UNK 105 107 107 UNK UNK V . n 
F 2 106 UNK 106 108 108 UNK UNK V . n 
F 2 107 UNK 107 109 109 UNK UNK V . n 
F 2 108 UNK 108 110 110 UNK UNK V . n 
F 2 109 UNK 109 111 111 UNK UNK V . n 
F 2 110 UNK 110 112 112 UNK UNK V . n 
F 2 111 TRP 111 113 113 TRP TRP V . n 
F 2 112 GLY 112 114 114 GLY GLY V . n 
F 2 113 UNK 113 115 115 UNK UNK V . n 
F 2 114 GLY 114 116 116 GLY GLY V . n 
F 2 115 THR 115 117 117 THR THR V . n 
F 2 116 UNK 116 118 118 UNK UNK V . n 
F 2 117 VAL 117 119 119 VAL VAL V . n 
F 2 118 THR 118 120 120 THR THR V . n 
F 2 119 VAL 119 121 121 VAL VAL V . n 
F 2 120 SER 120 122 ?   ?   ?   V . n 
F 2 121 SER 121 123 ?   ?   ?   V . n 
F 2 122 HIS 122 124 ?   ?   ?   V . n 
F 2 123 HIS 123 125 ?   ?   ?   V . n 
F 2 124 HIS 124 126 ?   ?   ?   V . n 
F 2 125 HIS 125 127 ?   ?   ?   V . n 
F 2 126 HIS 126 128 ?   ?   ?   V . n 
F 2 127 HIS 127 129 ?   ?   ?   V . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
G 4 A2G 1 B A2G 1 L LIG 301 n 
G 4 SIA 2 B SIA 2 L LIG 301 n 
H 4 A2G 1 C A2G 1 M LIG 301 n 
H 4 SIA 2 C SIA 2 M LIG 301 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 5 SER 1  301 301 SER LIG H . 
J 6 GOL 1  302 4   GOL GOL H . 
K 7 PEG 1  303 11  PEG PEG H . 
L 5 SER 1  301 301 SER LIG I . 
M 6 GOL 1  302 2   GOL GOL I . 
N 6 GOL 1  303 9   GOL GOL I . 
O 6 GOL 1  304 10  GOL GOL I . 
P 7 PEG 1  305 301 PEG PEG I . 
Q 6 GOL 1  301 3   GOL GOL L . 
R 6 GOL 1  302 6   GOL GOL L . 
S 6 GOL 1  301 5   GOL GOL M . 
T 6 GOL 1  201 8   GOL GOL V . 
U 8 HOH 1  401 177 HOH HOH H . 
U 8 HOH 2  402 35  HOH HOH H . 
U 8 HOH 3  403 220 HOH HOH H . 
U 8 HOH 4  404 45  HOH HOH H . 
U 8 HOH 5  405 6   HOH HOH H . 
U 8 HOH 6  406 87  HOH HOH H . 
U 8 HOH 7  407 144 HOH HOH H . 
U 8 HOH 8  408 120 HOH HOH H . 
U 8 HOH 9  409 68  HOH HOH H . 
U 8 HOH 10 410 105 HOH HOH H . 
U 8 HOH 11 411 169 HOH HOH H . 
U 8 HOH 12 412 175 HOH HOH H . 
U 8 HOH 13 413 9   HOH HOH H . 
U 8 HOH 14 414 54  HOH HOH H . 
U 8 HOH 15 415 214 HOH HOH H . 
U 8 HOH 16 416 195 HOH HOH H . 
U 8 HOH 17 417 128 HOH HOH H . 
U 8 HOH 18 418 73  HOH HOH H . 
U 8 HOH 19 419 40  HOH HOH H . 
U 8 HOH 20 420 198 HOH HOH H . 
U 8 HOH 21 421 75  HOH HOH H . 
U 8 HOH 22 422 81  HOH HOH H . 
U 8 HOH 23 423 39  HOH HOH H . 
U 8 HOH 24 424 103 HOH HOH H . 
U 8 HOH 25 425 24  HOH HOH H . 
U 8 HOH 26 426 127 HOH HOH H . 
U 8 HOH 27 427 52  HOH HOH H . 
U 8 HOH 28 428 44  HOH HOH H . 
U 8 HOH 29 429 76  HOH HOH H . 
U 8 HOH 30 430 38  HOH HOH H . 
U 8 HOH 31 431 183 HOH HOH H . 
U 8 HOH 32 432 202 HOH HOH H . 
U 8 HOH 33 433 223 HOH HOH H . 
U 8 HOH 34 434 179 HOH HOH H . 
U 8 HOH 35 435 98  HOH HOH H . 
V 8 HOH 1  401 123 HOH HOH I . 
V 8 HOH 2  402 222 HOH HOH I . 
V 8 HOH 3  403 3   HOH HOH I . 
V 8 HOH 4  404 143 HOH HOH I . 
V 8 HOH 5  405 112 HOH HOH I . 
V 8 HOH 6  406 141 HOH HOH I . 
V 8 HOH 7  407 126 HOH HOH I . 
V 8 HOH 8  408 106 HOH HOH I . 
V 8 HOH 9  409 55  HOH HOH I . 
V 8 HOH 10 410 124 HOH HOH I . 
V 8 HOH 11 411 97  HOH HOH I . 
V 8 HOH 12 412 138 HOH HOH I . 
V 8 HOH 13 413 2   HOH HOH I . 
V 8 HOH 14 414 113 HOH HOH I . 
V 8 HOH 15 415 166 HOH HOH I . 
V 8 HOH 16 416 192 HOH HOH I . 
V 8 HOH 17 417 67  HOH HOH I . 
V 8 HOH 18 418 63  HOH HOH I . 
V 8 HOH 19 419 70  HOH HOH I . 
V 8 HOH 20 420 53  HOH HOH I . 
V 8 HOH 21 421 160 HOH HOH I . 
V 8 HOH 22 422 111 HOH HOH I . 
V 8 HOH 23 423 146 HOH HOH I . 
V 8 HOH 24 424 185 HOH HOH I . 
V 8 HOH 25 425 37  HOH HOH I . 
V 8 HOH 26 426 209 HOH HOH I . 
V 8 HOH 27 427 84  HOH HOH I . 
V 8 HOH 28 428 66  HOH HOH I . 
V 8 HOH 29 429 217 HOH HOH I . 
V 8 HOH 30 430 41  HOH HOH I . 
V 8 HOH 31 431 125 HOH HOH I . 
V 8 HOH 32 432 216 HOH HOH I . 
V 8 HOH 33 433 145 HOH HOH I . 
V 8 HOH 34 434 8   HOH HOH I . 
V 8 HOH 35 435 42  HOH HOH I . 
V 8 HOH 36 436 26  HOH HOH I . 
V 8 HOH 37 437 74  HOH HOH I . 
V 8 HOH 38 438 58  HOH HOH I . 
V 8 HOH 39 439 189 HOH HOH I . 
V 8 HOH 40 440 88  HOH HOH I . 
V 8 HOH 41 441 80  HOH HOH I . 
V 8 HOH 42 442 140 HOH HOH I . 
V 8 HOH 43 443 188 HOH HOH I . 
V 8 HOH 44 444 108 HOH HOH I . 
V 8 HOH 45 445 136 HOH HOH I . 
V 8 HOH 46 446 130 HOH HOH I . 
V 8 HOH 47 447 168 HOH HOH I . 
V 8 HOH 48 448 61  HOH HOH I . 
V 8 HOH 49 449 211 HOH HOH I . 
V 8 HOH 50 450 60  HOH HOH I . 
V 8 HOH 51 451 30  HOH HOH I . 
V 8 HOH 52 452 119 HOH HOH I . 
V 8 HOH 53 453 170 HOH HOH I . 
V 8 HOH 54 454 104 HOH HOH I . 
V 8 HOH 55 455 182 HOH HOH I . 
V 8 HOH 56 456 167 HOH HOH I . 
V 8 HOH 57 457 96  HOH HOH I . 
V 8 HOH 58 458 196 HOH HOH I . 
V 8 HOH 59 459 200 HOH HOH I . 
V 8 HOH 60 460 151 HOH HOH I . 
V 8 HOH 61 461 206 HOH HOH I . 
V 8 HOH 62 462 199 HOH HOH I . 
W 8 HOH 1  201 100 HOH HOH K . 
W 8 HOH 2  202 10  HOH HOH K . 
W 8 HOH 3  203 154 HOH HOH K . 
W 8 HOH 4  204 173 HOH HOH K . 
W 8 HOH 5  205 71  HOH HOH K . 
W 8 HOH 6  206 134 HOH HOH K . 
W 8 HOH 7  207 83  HOH HOH K . 
W 8 HOH 8  208 184 HOH HOH K . 
W 8 HOH 9  209 191 HOH HOH K . 
W 8 HOH 10 210 115 HOH HOH K . 
X 8 HOH 1  401 131 HOH HOH L . 
X 8 HOH 2  402 59  HOH HOH L . 
X 8 HOH 3  403 36  HOH HOH L . 
X 8 HOH 4  404 187 HOH HOH L . 
X 8 HOH 5  405 174 HOH HOH L . 
X 8 HOH 6  406 117 HOH HOH L . 
X 8 HOH 7  407 72  HOH HOH L . 
X 8 HOH 8  408 159 HOH HOH L . 
X 8 HOH 9  409 204 HOH HOH L . 
X 8 HOH 10 410 157 HOH HOH L . 
X 8 HOH 11 411 14  HOH HOH L . 
X 8 HOH 12 412 150 HOH HOH L . 
X 8 HOH 13 413 47  HOH HOH L . 
X 8 HOH 14 414 11  HOH HOH L . 
X 8 HOH 15 415 193 HOH HOH L . 
X 8 HOH 16 416 28  HOH HOH L . 
X 8 HOH 17 417 122 HOH HOH L . 
X 8 HOH 18 418 50  HOH HOH L . 
X 8 HOH 19 419 162 HOH HOH L . 
X 8 HOH 20 420 15  HOH HOH L . 
X 8 HOH 21 421 22  HOH HOH L . 
X 8 HOH 22 422 194 HOH HOH L . 
X 8 HOH 23 423 20  HOH HOH L . 
X 8 HOH 24 424 18  HOH HOH L . 
X 8 HOH 25 425 109 HOH HOH L . 
X 8 HOH 26 426 137 HOH HOH L . 
X 8 HOH 27 427 210 HOH HOH L . 
X 8 HOH 28 428 118 HOH HOH L . 
X 8 HOH 29 429 77  HOH HOH L . 
X 8 HOH 30 430 5   HOH HOH L . 
X 8 HOH 31 431 178 HOH HOH L . 
X 8 HOH 32 432 1   HOH HOH L . 
X 8 HOH 33 433 176 HOH HOH L . 
X 8 HOH 34 434 49  HOH HOH L . 
X 8 HOH 35 435 133 HOH HOH L . 
X 8 HOH 36 436 65  HOH HOH L . 
X 8 HOH 37 437 135 HOH HOH L . 
X 8 HOH 38 438 4   HOH HOH L . 
X 8 HOH 39 439 164 HOH HOH L . 
X 8 HOH 40 440 205 HOH HOH L . 
X 8 HOH 41 441 156 HOH HOH L . 
X 8 HOH 42 442 153 HOH HOH L . 
X 8 HOH 43 443 86  HOH HOH L . 
X 8 HOH 44 444 13  HOH HOH L . 
X 8 HOH 45 445 46  HOH HOH L . 
X 8 HOH 46 446 92  HOH HOH L . 
X 8 HOH 47 447 221 HOH HOH L . 
X 8 HOH 48 448 121 HOH HOH L . 
X 8 HOH 49 449 17  HOH HOH L . 
X 8 HOH 50 450 107 HOH HOH L . 
X 8 HOH 51 451 197 HOH HOH L . 
X 8 HOH 52 452 161 HOH HOH L . 
X 8 HOH 53 453 181 HOH HOH L . 
X 8 HOH 54 454 31  HOH HOH L . 
X 8 HOH 55 455 132 HOH HOH L . 
X 8 HOH 56 456 208 HOH HOH L . 
X 8 HOH 57 457 190 HOH HOH L . 
Y 8 HOH 1  401 203 HOH HOH M . 
Y 8 HOH 2  402 94  HOH HOH M . 
Y 8 HOH 3  403 43  HOH HOH M . 
Y 8 HOH 4  404 29  HOH HOH M . 
Y 8 HOH 5  405 155 HOH HOH M . 
Y 8 HOH 6  406 23  HOH HOH M . 
Y 8 HOH 7  407 21  HOH HOH M . 
Y 8 HOH 8  408 7   HOH HOH M . 
Y 8 HOH 9  409 91  HOH HOH M . 
Y 8 HOH 10 410 186 HOH HOH M . 
Y 8 HOH 11 411 32  HOH HOH M . 
Y 8 HOH 12 412 215 HOH HOH M . 
Y 8 HOH 13 413 163 HOH HOH M . 
Y 8 HOH 14 414 62  HOH HOH M . 
Y 8 HOH 15 415 114 HOH HOH M . 
Y 8 HOH 16 416 99  HOH HOH M . 
Y 8 HOH 17 417 79  HOH HOH M . 
Y 8 HOH 18 418 172 HOH HOH M . 
Y 8 HOH 19 419 48  HOH HOH M . 
Y 8 HOH 20 420 12  HOH HOH M . 
Y 8 HOH 21 421 82  HOH HOH M . 
Y 8 HOH 22 422 142 HOH HOH M . 
Y 8 HOH 23 423 33  HOH HOH M . 
Y 8 HOH 24 424 51  HOH HOH M . 
Y 8 HOH 25 425 110 HOH HOH M . 
Y 8 HOH 26 426 25  HOH HOH M . 
Y 8 HOH 27 427 102 HOH HOH M . 
Y 8 HOH 28 428 148 HOH HOH M . 
Y 8 HOH 29 429 27  HOH HOH M . 
Y 8 HOH 30 430 158 HOH HOH M . 
Y 8 HOH 31 431 147 HOH HOH M . 
Y 8 HOH 32 432 90  HOH HOH M . 
Y 8 HOH 33 433 212 HOH HOH M . 
Y 8 HOH 34 434 171 HOH HOH M . 
Y 8 HOH 35 435 207 HOH HOH M . 
Y 8 HOH 36 436 69  HOH HOH M . 
Y 8 HOH 37 437 219 HOH HOH M . 
Y 8 HOH 38 438 129 HOH HOH M . 
Z 8 HOH 1  301 152 HOH HOH V . 
Z 8 HOH 2  302 89  HOH HOH V . 
Z 8 HOH 3  303 16  HOH HOH V . 
Z 8 HOH 4  304 101 HOH HOH V . 
Z 8 HOH 5  305 34  HOH HOH V . 
Z 8 HOH 6  306 19  HOH HOH V . 
Z 8 HOH 7  307 85  HOH HOH V . 
Z 8 HOH 8  308 64  HOH HOH V . 
Z 8 HOH 9  309 57  HOH HOH V . 
Z 8 HOH 10 310 93  HOH HOH V . 
Z 8 HOH 11 311 201 HOH HOH V . 
Z 8 HOH 12 312 213 HOH HOH V . 
Z 8 HOH 13 313 149 HOH HOH V . 
Z 8 HOH 14 314 218 HOH HOH V . 
Z 8 HOH 15 315 180 HOH HOH V . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.21rc1_5109: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                     2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                     3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .                     4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FXT 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     48.355 
_cell.length_a_esd                 ? 
_cell.length_b                     125.277 
_cell.length_b_esd                 ? 
_cell.length_c                     190.759 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FXT 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FXT 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.53 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.43 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '22% PEG 3350, 0.1M NH4Cl pH7' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-10-19 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.67019 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.67019 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9FXT 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.3 
_reflns.d_resolution_low                               47.69 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     52514 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                23.27 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          15.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.170 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.166 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.30 2.44 ? ? ? ? ? ? 5942 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 1.3   ? ? 1 1 0.3   ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
2.44 2.61 ? ? ? ? ? ? 6983 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.96  ? ? 2 1 0.47  ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
2.61 2.81 ? ? ? ? ? ? 6723 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.57  ? ? 3 1 0.73  ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
2.81 3.08 ? ? ? ? ? ? 6190 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.3   ? ? 4 1 0.90  ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
3.08 3.44 ? ? ? ? ? ? 5543 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.16  ? ? 5 1 0.97  ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
3.44 3.97 ? ? ? ? ? ? 4831 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.09  ? ? 6 1 0.98  ? ? ? ? 0.08 ? ? ? ? ? ? ? ? ? 
3.97 4.86 ? ? ? ? ? ? 4108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.06  ? ? 7 1 0.994 ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
4.86 6.83 ? ? ? ? ? ? 3137 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.062 ? ? 8 1 0.993 ? ? ? ? ?    ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FXT 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.30 
_refine.ls_d_res_low                             47.69 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     52436 
_refine.ls_number_reflns_R_free                  2636 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.70 
_refine.ls_percent_reflns_R_free                 5.03 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2635 
_refine.ls_R_factor_R_free                       0.3121 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2610 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 32.49 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.37 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.30 
_refine_hist.d_res_low                        47.69 
_refine_hist.number_atoms_solvent             217 
_refine_hist.number_atoms_total               8110 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7749 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         144 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.002  ? ?    ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.652  ? ?    ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 13.662 ? 2773 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.043  ? 1267 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.004  ? 1393 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.30 2.34  . . 135 2447 96.00  . . . . 0.3294 . . . . . . . . . . . 0.3838 
'X-RAY DIFFRACTION' 2.34 2.39  . . 127 2543 98.00  . . . . 0.3105 . . . . . . . . . . . 0.3582 
'X-RAY DIFFRACTION' 2.39 2.44  . . 127 2640 100.00 . . . . 0.3090 . . . . . . . . . . . 0.3705 
'X-RAY DIFFRACTION' 2.44 2.49  . . 140 2553 100.00 . . . . 0.3118 . . . . . . . . . . . 0.3698 
'X-RAY DIFFRACTION' 2.49 2.55  . . 131 2652 100.00 . . . . 0.3203 . . . . . . . . . . . 0.3817 
'X-RAY DIFFRACTION' 2.55 2.61  . . 136 2549 100.00 . . . . 0.3289 . . . . . . . . . . . 0.3934 
'X-RAY DIFFRACTION' 2.61 2.68  . . 148 2633 100.00 . . . . 0.3173 . . . . . . . . . . . 0.4758 
'X-RAY DIFFRACTION' 2.68 2.76  . . 141 2537 100.00 . . . . 0.3060 . . . . . . . . . . . 0.3584 
'X-RAY DIFFRACTION' 2.76 2.85  . . 168 2639 100.00 . . . . 0.2918 . . . . . . . . . . . 0.3644 
'X-RAY DIFFRACTION' 2.85 2.95  . . 134 2552 100.00 . . . . 0.2748 . . . . . . . . . . . 0.3320 
'X-RAY DIFFRACTION' 2.95 3.07  . . 131 2638 100.00 . . . . 0.2709 . . . . . . . . . . . 0.3113 
'X-RAY DIFFRACTION' 3.07 3.21  . . 137 2633 100.00 . . . . 0.2696 . . . . . . . . . . . 0.2826 
'X-RAY DIFFRACTION' 3.21 3.38  . . 150 2587 100.00 . . . . 0.2842 . . . . . . . . . . . 0.3507 
'X-RAY DIFFRACTION' 3.38 3.59  . . 131 2650 100.00 . . . . 0.2643 . . . . . . . . . . . 0.3007 
'X-RAY DIFFRACTION' 3.59 3.87  . . 134 2643 100.00 . . . . 0.2501 . . . . . . . . . . . 0.3023 
'X-RAY DIFFRACTION' 3.87 4.25  . . 146 2648 100.00 . . . . 0.2362 . . . . . . . . . . . 0.2716 
'X-RAY DIFFRACTION' 4.25 4.87  . . 143 2692 100.00 . . . . 0.2203 . . . . . . . . . . . 0.2530 
'X-RAY DIFFRACTION' 4.87 6.13  . . 139 2710 100.00 . . . . 0.2398 . . . . . . . . . . . 0.2945 
'X-RAY DIFFRACTION' 6.13 47.69 . . 138 2854 100.00 . . . . 0.2363 . . . . . . . . . . . 0.2944 
# 
_struct.entry_id                     9FXT 
_struct.title                        'L2A5 Fab in complex with STn-Ser' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FXT 
_struct_keywords.text            'Antibody, Fab, SUGAR BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'SUGAR BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 6 ? 
K N N 7 ? 
L N N 5 ? 
M N N 6 ? 
N N N 6 ? 
O N N 6 ? 
P N N 7 ? 
Q N N 6 ? 
R N N 6 ? 
S N N 6 ? 
T N N 6 ? 
U N N 8 ? 
V N N 8 ? 
W N N 8 ? 
X N N 8 ? 
Y N N 8 ? 
Z N N 8 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9FXT 9FXT ? 1 ? 1 
2 PDB 9FXT 9FXT ? 2 ? 1 
3 PDB 9FXT 9FXT ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FXT H 1 ? 216 ? 9FXT 1 ? 216 ? 1 216 
2 1 9FXT I 1 ? 216 ? 9FXT 1 ? 216 ? 1 216 
3 2 9FXT K 1 ? 127 ? 9FXT 3 ? 129 ? 3 129 
4 3 9FXT L 1 ? 215 ? 9FXT 1 ? 214 ? 1 214 
5 3 9FXT M 1 ? 215 ? 9FXT 1 ? 214 ? 1 214 
6 2 9FXT V 1 ? 127 ? 9FXT 3 ? 129 ? 3 129 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? trimeric 3 
2 author_defined_assembly ? trimeric 3 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,E,H,I,J,K,S,U,W,Y         
2 1 B,D,F,G,L,M,N,O,P,Q,R,T,V,X,Z 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 64  ? ILE A 68  ? LEU H 63  ILE H 67  5 ? 5 
HELX_P HELX_P2  AA2 THR A 87  ? THR A 91  ? THR H 83  THR H 87  5 ? 5 
HELX_P HELX_P3  AA3 SER A 156 ? ALA A 158 ? SER H 156 ALA H 158 5 ? 3 
HELX_P HELX_P4  AA4 SER A 187 ? LEU A 189 ? SER H 187 LEU H 189 5 ? 3 
HELX_P HELX_P5  AA5 PRO B 62  ? LYS B 65  ? PRO I 61  LYS I 64  5 ? 4 
HELX_P HELX_P6  AA6 THR B 87  ? THR B 91  ? THR I 83  THR I 87  5 ? 5 
HELX_P HELX_P7  AA7 SER B 127 ? LYS B 129 ? SER I 127 LYS I 129 5 ? 3 
HELX_P HELX_P8  AA8 SER B 156 ? ALA B 158 ? SER I 156 ALA I 158 5 ? 3 
HELX_P HELX_P9  AA9 SER B 187 ? LEU B 189 ? SER I 187 LEU I 189 5 ? 3 
HELX_P HELX_P10 AB1 LYS B 201 ? ASN B 204 ? LYS I 201 ASN I 204 5 ? 4 
HELX_P HELX_P11 AB2 UNK C 87  ? UNK C 91  ? UNK K 89  UNK K 93  5 ? 5 
HELX_P HELX_P12 AB3 GLU D 78  ? ALA D 82  ? GLU L 79  ALA L 83  5 ? 5 
HELX_P HELX_P13 AB4 SER D 122 ? LYS D 127 ? SER L 121 LYS L 126 1 ? 6 
HELX_P HELX_P14 AB5 LYS D 184 ? LYS D 189 ? LYS L 183 LYS L 188 1 ? 6 
HELX_P HELX_P15 AB6 GLU E 78  ? ALA E 82  ? GLU M 79  ALA M 83  5 ? 5 
HELX_P HELX_P16 AB7 SER E 122 ? LYS E 127 ? SER M 121 LYS M 126 1 ? 6 
HELX_P HELX_P17 AB8 LYS E 184 ? LYS E 189 ? LYS M 183 LYS M 188 1 ? 6 
HELX_P HELX_P18 AB9 UNK F 74  ? UNK F 76  ? UNK V 76  UNK V 78  5 ? 3 
HELX_P HELX_P19 AC1 UNK F 87  ? UNK F 91  ? UNK V 89  UNK V 93  5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 22  SG ? ? ? 1_555 A CYS 96  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ?    ? A CYS 140 SG ? ? ? 1_555 A CYS 196 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ?    ? B CYS 22  SG ? ? ? 1_555 B CYS 96  SG ? ? I CYS 22  I CYS 92  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf4 disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 196 SG ? ? I CYS 140 I CYS 196 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf5 disulf ?    ? D CYS 23  SG ? ? ? 1_555 D CYS 87  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf6 disulf ?    ? D CYS 135 SG ? ? ? 1_555 D CYS 195 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf7 disulf ?    ? E CYS 23  SG ? ? ? 1_555 E CYS 87  SG ? ? M CYS 23  M CYS 88  1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf8 disulf ?    ? E CYS 135 SG ? ? ? 1_555 E CYS 195 SG ? ? M CYS 134 M CYS 194 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
covale1 covale one  ? I SER .   OG ? ? ? 1_555 H A2G .   C1 ? ? H SER 301 C A2G 1   1_555 ? ? ? ? ? ? ? 1.397 ? ? 
covale2 covale one  ? L SER .   OG ? ? ? 1_555 G A2G .   C1 ? ? I SER 301 B A2G 1   1_555 ? ? ? ? ? ? ? 1.397 ? ? 
covale3 covale both ? G A2G .   O6 ? ? ? 1_555 G SIA .   C2 ? ? B A2G 1   B SIA 2   1_555 ? ? ? ? ? ? ? 1.401 ? ? 
covale4 covale both ? H A2G .   O6 ? ? ? 1_555 H SIA .   C2 ? ? C A2G 1   C SIA 2   1_555 ? ? ? ? ? ? ? 1.403 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 22  ? CYS A 96  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 140 ? CYS A 196 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 22  ? CYS B 96  ? CYS I 22  ? 1_555 CYS I 92  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 140 ? CYS B 196 ? CYS I 140 ? 1_555 CYS I 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS D 23  ? CYS D 87  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS D 135 ? CYS D 195 ? CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7 CYS E 23  ? CYS E 87  ? CYS M 23  ? 1_555 CYS M 88  ? 1_555 SG SG . . . None 'Disulfide bridge' 
8 CYS E 135 ? CYS E 195 ? CYS M 134 ? 1_555 CYS M 194 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 146 A . ? PHE 146 H PRO 147 A ? PRO 147 H 1 -5.22 
2 GLU 148 A . ? GLU 148 H PRO 149 A ? PRO 149 H 1 -2.12 
3 PHE 146 B . ? PHE 146 I PRO 147 B ? PRO 147 I 1 -4.92 
4 GLU 148 B . ? GLU 148 I PRO 149 B ? PRO 149 I 1 -2.15 
5 THR 7   D . ? THR 7   L PRO 8   D ? PRO 8   L 1 -4.67 
6 TYR 141 D . ? TYR 140 L PRO 142 D ? PRO 141 L 1 0.91  
7 THR 7   E . ? THR 7   M PRO 8   E ? PRO 8   M 1 -4.73 
8 TYR 141 E . ? TYR 140 M PRO 142 E ? PRO 141 M 1 0.85  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 3 ? 
AB4 ? 4 ? 
AB5 ? 6 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 6 ? 
AB9 ? 4 ? 
AC1 ? 4 ? 
AC2 ? 4 ? 
AC3 ? 4 ? 
AC4 ? 6 ? 
AC5 ? 4 ? 
AC6 ? 4 ? 
AC7 ? 4 ? 
AC8 ? 4 ? 
AC9 ? 6 ? 
AD1 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? parallel      
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB8 4 5 ? anti-parallel 
AB8 5 6 ? anti-parallel 
AB9 1 2 ? parallel      
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? parallel      
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC4 4 5 ? anti-parallel 
AC4 5 6 ? anti-parallel 
AC5 1 2 ? parallel      
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
AC9 1 2 ? parallel      
AC9 2 3 ? anti-parallel 
AC9 3 4 ? anti-parallel 
AC9 4 5 ? anti-parallel 
AC9 5 6 ? anti-parallel 
AD1 1 2 ? parallel      
AD1 2 3 ? anti-parallel 
AD1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 5   ? SER A 7   ? GLN H 5   SER H 7   
AA1 2 SER A 17  ? SER A 23  ? SER H 17  SER H 23  
AA1 3 GLN A 78  ? ASN A 84  A GLN H 77  ASN H 82  
AA1 4 THR A 71  ? ASP A 73  ? THR H 70  ASP H 72  
AA2 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA2 2 THR A 107 ? VAL A 111 ? THR H 107 VAL H 111 
AA2 3 ALA A 92  ? ARG A 98  ? ALA H 88  ARG H 94  
AA2 4 TRP A 35  ? GLN A 40  ? TRP H 35  GLN H 39  
AA2 5 LEU A 46  ? ILE A 52  ? LEU H 45  ILE H 51  
AA3 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA3 2 THR A 107 ? VAL A 111 ? THR H 107 VAL H 111 
AA3 3 ALA A 92  ? ARG A 98  ? ALA H 88  ARG H 94  
AA3 4 TYR A 102 ? TRP A 103 ? TYR H 102 TRP H 103 
AA4 1 SER A 120 ? LEU A 124 ? SER H 120 LEU H 124 
AA4 2 THR A 135 ? TYR A 145 ? THR H 135 TYR H 145 
AA4 3 TYR A 176 ? PRO A 185 ? TYR H 176 PRO H 185 
AA4 4 VAL A 163 ? THR A 165 ? VAL H 163 THR H 165 
AA5 1 SER A 120 ? LEU A 124 ? SER H 120 LEU H 124 
AA5 2 THR A 135 ? TYR A 145 ? THR H 135 TYR H 145 
AA5 3 TYR A 176 ? PRO A 185 ? TYR H 176 PRO H 185 
AA5 4 VAL A 169 ? LEU A 170 ? VAL H 169 LEU H 170 
AA6 1 THR A 151 ? TRP A 154 ? THR H 151 TRP H 154 
AA6 2 ILE A 195 ? HIS A 200 ? ILE H 195 HIS H 200 
AA6 3 THR A 205 ? ARG A 210 ? THR H 205 ARG H 210 
AA7 1 GLN B 3   ? SER B 7   ? GLN I 3   SER I 7   
AA7 2 LEU B 18  ? ILE B 25  ? LEU I 18  ILE I 25  
AA7 3 GLN B 78  ? LEU B 83  ? GLN I 77  LEU I 82  
AA7 4 ILE B 68  ? ASP B 73  ? ILE I 67  ASP I 72  
AA8 1 LEU B 11  ? VAL B 12  ? LEU I 11  VAL I 12  
AA8 2 THR B 107 ? VAL B 111 ? THR I 107 VAL I 111 
AA8 3 ALA B 92  ? ARG B 98  ? ALA I 88  ARG I 94  
AA8 4 TRP B 35  ? GLN B 40  ? TRP I 35  GLN I 39  
AA8 5 LEU B 46  ? ILE B 52  ? LEU I 45  ILE I 51  
AA8 6 ASN B 58  ? TYR B 60  ? ASN I 57  TYR I 59  
AA9 1 LEU B 11  ? VAL B 12  ? LEU I 11  VAL I 12  
AA9 2 THR B 107 ? VAL B 111 ? THR I 107 VAL I 111 
AA9 3 ALA B 92  ? ARG B 98  ? ALA I 88  ARG I 94  
AA9 4 TYR B 102 ? TRP B 103 ? TYR I 102 TRP I 103 
AB1 1 SER B 120 ? LEU B 124 ? SER I 120 LEU I 124 
AB1 2 THR B 135 ? TYR B 145 ? THR I 135 TYR I 145 
AB1 3 TYR B 176 ? PRO B 185 ? TYR I 176 PRO I 185 
AB1 4 VAL B 163 ? THR B 165 ? VAL I 163 THR I 165 
AB2 1 THR B 131 ? SER B 132 ? THR I 131 SER I 132 
AB2 2 THR B 135 ? TYR B 145 ? THR I 135 TYR I 145 
AB2 3 TYR B 176 ? PRO B 185 ? TYR I 176 PRO I 185 
AB2 4 VAL B 169 ? LEU B 170 ? VAL I 169 LEU I 170 
AB3 1 THR B 151 ? TRP B 154 ? THR I 151 TRP I 154 
AB3 2 ILE B 195 ? HIS B 200 ? ILE I 195 HIS I 200 
AB3 3 THR B 205 ? ARG B 210 ? THR I 205 ARG I 210 
AB4 1 GLN C 3   ? SER C 7   ? GLN K 5   SER K 9   
AB4 2 LEU C 18  ? UNK C 25  ? LEU K 20  UNK K 27  
AB4 3 UNK C 78  ? UNK C 83  ? UNK K 80  UNK K 85  
AB4 4 PHE C 68  ? ASP C 73  ? PHE K 70  ASP K 75  
AB5 1 GLY C 10  ? VAL C 12  ? GLY K 12  VAL K 14  
AB5 2 THR C 115 ? VAL C 119 ? THR K 117 VAL K 121 
AB5 3 ALA C 92  ? UNK C 99  ? ALA K 94  UNK K 101 
AB5 4 UNK C 34  ? GLN C 39  ? UNK K 36  GLN K 41  
AB5 5 GLU C 46  ? UNK C 51  ? GLU K 48  UNK K 53  
AB5 6 UNK C 58  ? UNK C 60  ? UNK K 60  UNK K 62  
AB6 1 GLY C 10  ? VAL C 12  ? GLY K 12  VAL K 14  
AB6 2 THR C 115 ? VAL C 119 ? THR K 117 VAL K 121 
AB6 3 ALA C 92  ? UNK C 99  ? ALA K 94  UNK K 101 
AB6 4 UNK C 108 ? TRP C 111 ? UNK K 110 TRP K 113 
AB7 1 LEU D 4   ? THR D 7   ? LEU L 4   THR L 7   
AB7 2 VAL D 19  ? ALA D 25  ? VAL L 19  ALA L 25  
AB7 3 SER D 69  ? ILE D 74  ? SER L 70  ILE L 75  
AB7 4 PHE D 61  ? SER D 66  ? PHE L 62  SER L 67  
AB8 1 ILE D 10  ? ALA D 13  ? ILE L 10  ALA L 13  
AB8 2 THR D 103 ? LEU D 107 ? THR L 102 LEU L 106 
AB8 3 ALA D 83  ? SER D 91  ? ALA L 84  SER L 92  
AB8 4 HIS D 33  ? GLN D 37  ? HIS L 34  GLN L 38  
AB8 5 LYS D 44  ? TYR D 48  ? LYS L 45  TYR L 49  
AB8 6 LYS D 52  ? LEU D 53  ? LYS L 53  LEU L 54  
AB9 1 ILE D 10  ? ALA D 13  ? ILE L 10  ALA L 13  
AB9 2 THR D 103 ? LEU D 107 ? THR L 102 LEU L 106 
AB9 3 ALA D 83  ? SER D 91  ? ALA L 84  SER L 92  
AB9 4 MET D 96  B PHE D 99  ? MET L 95  PHE L 98  
AC1 1 SER D 115 ? PHE D 119 ? SER L 114 PHE L 118 
AC1 2 THR D 130 ? PHE D 140 ? THR L 129 PHE L 139 
AC1 3 TYR D 174 ? SER D 183 ? TYR L 173 SER L 182 
AC1 4 SER D 160 ? VAL D 164 ? SER L 159 VAL L 163 
AC2 1 ALA D 154 ? LEU D 155 ? ALA L 153 LEU L 154 
AC2 2 ALA D 145 ? VAL D 151 ? ALA L 144 VAL L 150 
AC2 3 VAL D 192 ? HIS D 199 ? VAL L 191 HIS L 198 
AC2 4 VAL D 206 ? ASN D 211 ? VAL L 205 ASN L 210 
AC3 1 THR E 5   ? THR E 7   ? THR M 5   THR M 7   
AC3 2 VAL E 19  ? SER E 24  ? VAL M 19  SER M 24  
AC3 3 SER E 69  ? ILE E 74  ? SER M 70  ILE M 75  
AC3 4 PHE E 61  ? SER E 66  ? PHE M 62  SER M 67  
AC4 1 ILE E 10  ? ALA E 13  ? ILE M 10  ALA M 13  
AC4 2 THR E 103 ? LEU E 107 ? THR M 102 LEU M 106 
AC4 3 ALA E 83  ? SER E 91  ? ALA M 84  SER M 92  
AC4 4 HIS E 33  ? GLN E 37  ? HIS M 34  GLN M 38  
AC4 5 LYS E 44  ? TYR E 48  ? LYS M 45  TYR M 49  
AC4 6 LYS E 52  ? LEU E 53  ? LYS M 53  LEU M 54  
AC5 1 ILE E 10  ? ALA E 13  ? ILE M 10  ALA M 13  
AC5 2 THR E 103 ? LEU E 107 ? THR M 102 LEU M 106 
AC5 3 ALA E 83  ? SER E 91  ? ALA M 84  SER M 92  
AC5 4 MET E 96  B PHE E 99  ? MET M 95  PHE M 98  
AC6 1 SER E 115 ? PHE E 119 ? SER M 114 PHE M 118 
AC6 2 THR E 130 ? PHE E 140 ? THR M 129 PHE M 139 
AC6 3 TYR E 174 ? SER E 183 ? TYR M 173 SER M 182 
AC6 4 SER E 160 ? VAL E 164 ? SER M 159 VAL M 163 
AC7 1 ALA E 154 ? LEU E 155 ? ALA M 153 LEU M 154 
AC7 2 LYS E 146 ? VAL E 151 ? LYS M 145 VAL M 150 
AC7 3 VAL E 192 ? THR E 198 ? VAL M 191 THR M 197 
AC7 4 VAL E 206 ? ASN E 211 ? VAL M 205 ASN M 210 
AC8 1 GLN F 3   ? SER F 7   ? GLN V 5   SER V 9   
AC8 2 SER F 17  ? UNK F 25  ? SER V 19  UNK V 27  
AC8 3 UNK F 78  ? UNK F 84  ? UNK V 80  UNK V 86  
AC8 4 PHE F 68  ? ASP F 73  ? PHE V 70  ASP V 75  
AC9 1 GLY F 10  ? UNK F 11  ? GLY V 12  UNK V 13  
AC9 2 THR F 115 ? THR F 118 ? THR V 117 THR V 120 
AC9 3 ALA F 92  ? UNK F 98  ? ALA V 94  UNK V 100 
AC9 4 UNK F 34  ? GLN F 39  ? UNK V 36  GLN V 41  
AC9 5 GLU F 46  ? UNK F 51  ? GLU V 48  UNK V 53  
AC9 6 UNK F 58  ? UNK F 60  ? UNK V 60  UNK V 62  
AD1 1 GLY F 10  ? UNK F 11  ? GLY V 12  UNK V 13  
AD1 2 THR F 115 ? THR F 118 ? THR V 117 THR V 120 
AD1 3 ALA F 92  ? UNK F 98  ? ALA V 94  UNK V 100 
AD1 4 UNK F 110 ? TRP F 111 ? UNK V 112 TRP V 113 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O THR A 21  ? O THR H 21  
AA1 2 3 N LEU A 18  ? N LEU H 18  O LEU A 83  ? O LEU H 82  
AA1 3 4 O GLN A 78  ? O GLN H 77  N ASP A 73  ? N ASP H 72  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 110 ? O THR H 110 
AA2 2 3 O THR A 107 ? O THR H 107 N TYR A 94  ? N TYR H 90  
AA2 3 4 O TYR A 95  ? O TYR H 91  N ILE A 38  ? N ILE H 37  
AA2 4 5 N TRP A 37  ? N TRP H 36  O MET A 49  ? O MET H 48  
AA3 1 2 N VAL A 12  ? N VAL H 12  O THR A 110 ? O THR H 110 
AA3 2 3 O THR A 107 ? O THR H 107 N TYR A 94  ? N TYR H 90  
AA3 3 4 N ARG A 98  ? N ARG H 94  O TYR A 102 ? O TYR H 102 
AA4 1 2 N PHE A 122 ? N PHE H 122 O LEU A 141 ? O LEU H 141 
AA4 2 3 N TYR A 145 ? N TYR H 145 O TYR A 176 ? O TYR H 176 
AA4 3 4 O VAL A 181 ? O VAL H 181 N HIS A 164 ? N HIS H 164 
AA5 1 2 N PHE A 122 ? N PHE H 122 O LEU A 141 ? O LEU H 141 
AA5 2 3 N TYR A 145 ? N TYR H 145 O TYR A 176 ? O TYR H 176 
AA5 3 4 O SER A 177 ? O SER H 177 N VAL A 169 ? N VAL H 169 
AA6 1 2 N SER A 153 ? N SER H 153 O ASN A 197 ? O ASN H 197 
AA6 2 3 N HIS A 200 ? N HIS H 200 O THR A 205 ? O THR H 205 
AA7 1 2 N SER B 7   ? N SER I 7   O THR B 21  ? O THR I 21  
AA7 2 3 N LEU B 18  ? N LEU I 18  O LEU B 83  ? O LEU I 82  
AA7 3 4 O GLN B 78  ? O GLN I 77  N ASP B 73  ? N ASP I 72  
AA8 1 2 N VAL B 12  ? N VAL I 12  O THR B 110 ? O THR I 110 
AA8 2 3 O THR B 107 ? O THR I 107 N TYR B 94  ? N TYR I 90  
AA8 3 4 O TYR B 95  ? O TYR I 91  N ILE B 38  ? N ILE I 37  
AA8 4 5 N ARG B 39  ? N ARG I 38  O GLU B 47  ? O GLU I 46  
AA8 5 6 N SER B 51  ? N SER I 50  O ILE B 59  ? O ILE I 58  
AA9 1 2 N VAL B 12  ? N VAL I 12  O THR B 110 ? O THR I 110 
AA9 2 3 O THR B 107 ? O THR I 107 N TYR B 94  ? N TYR I 90  
AA9 3 4 N ARG B 98  ? N ARG I 94  O TYR B 102 ? O TYR I 102 
AB1 1 2 N PHE B 122 ? N PHE I 122 O LEU B 141 ? O LEU I 141 
AB1 2 3 N TYR B 145 ? N TYR I 145 O TYR B 176 ? O TYR I 176 
AB1 3 4 O VAL B 181 ? O VAL I 181 N HIS B 164 ? N HIS I 164 
AB2 1 2 N SER B 132 ? N SER I 132 O THR B 135 ? O THR I 135 
AB2 2 3 N TYR B 145 ? N TYR I 145 O TYR B 176 ? O TYR I 176 
AB2 3 4 O SER B 177 ? O SER I 177 N VAL B 169 ? N VAL I 169 
AB3 1 2 N SER B 153 ? N SER I 153 O ASN B 197 ? O ASN I 197 
AB3 2 3 N HIS B 200 ? N HIS I 200 O THR B 205 ? O THR I 205 
AB4 1 2 N SER C 7   ? N SER K 9   O SER C 21  ? O SER K 23  
AB4 2 3 N LEU C 18  ? N LEU K 20  O UNK C 83  ? O UNK K 85  
AB4 3 4 O GLN C 82  ? O GLN K 84  N THR C 69  ? N THR K 71  
AB5 1 2 N VAL C 12  ? N VAL K 14  O THR C 118 ? O THR K 120 
AB5 2 3 O VAL C 117 ? O VAL K 119 N ALA C 92  ? N ALA K 94  
AB5 3 4 O UNK C 93  ? O UNK K 95  N GLN C 39  ? N GLN K 41  
AB5 4 5 N ARG C 38  ? N ARG K 40  O GLU C 46  ? O GLU K 48  
AB5 5 6 N UNK C 50  ? N UNK K 52  O UNK C 59  ? O UNK K 61  
AB6 1 2 N VAL C 12  ? N VAL K 14  O THR C 118 ? O THR K 120 
AB6 2 3 O VAL C 117 ? O VAL K 119 N ALA C 92  ? N ALA K 94  
AB6 3 4 N UNK C 98  ? N UNK K 100 O UNK C 110 ? O UNK K 112 
AB7 1 2 N THR D 5   ? N THR L 5   O SER D 24  ? O SER L 24  
AB7 2 3 N LEU D 21  ? N LEU L 21  O LEU D 72  ? O LEU L 73  
AB7 3 4 O THR D 73  ? O THR L 74  N SER D 62  ? N SER L 63  
AB8 1 2 N MET D 11  ? N MET L 11  O LYS D 104 ? O LYS L 103 
AB8 2 3 O LEU D 105 ? O LEU L 104 N ALA D 83  ? N ALA L 84  
AB8 3 4 O ALA D 84  ? O ALA L 85  N GLN D 37  ? N GLN L 38  
AB8 4 5 N GLN D 36  ? N GLN L 37  O LYS D 44  ? O LYS L 45  
AB8 5 6 N TYR D 48  ? N TYR L 49  O LYS D 52  ? O LYS L 53  
AB9 1 2 N MET D 11  ? N MET L 11  O LYS D 104 ? O LYS L 103 
AB9 2 3 O LEU D 105 ? O LEU L 104 N ALA D 83  ? N ALA L 84  
AB9 3 4 N SER D 91  ? N SER L 92  O MET D 96  B O MET L 95  
AC1 1 2 N PHE D 117 ? N PHE L 116 O LEU D 136 ? O LEU L 135 
AC1 2 3 N PHE D 140 ? N PHE L 139 O TYR D 174 ? O TYR L 173 
AC1 3 4 O THR D 179 ? O THR L 178 N GLN D 161 ? N GLN L 160 
AC2 1 2 O ALA D 154 ? O ALA L 153 N VAL D 151 ? N VAL L 150 
AC2 2 3 N LYS D 150 ? N LYS L 149 O ALA D 194 ? O ALA L 193 
AC2 3 4 N VAL D 197 ? N VAL L 196 O VAL D 206 ? O VAL L 205 
AC3 1 2 N THR E 5   ? N THR M 5   O SER E 24  ? O SER M 24  
AC3 2 3 N LEU E 21  ? N LEU M 21  O LEU E 72  ? O LEU M 73  
AC3 3 4 O THR E 73  ? O THR M 74  N SER E 62  ? N SER M 63  
AC4 1 2 N MET E 11  ? N MET M 11  O LYS E 104 ? O LYS M 103 
AC4 2 3 O LEU E 105 ? O LEU M 104 N ALA E 83  ? N ALA M 84  
AC4 3 4 O ALA E 84  ? O ALA M 85  N GLN E 37  ? N GLN M 38  
AC4 4 5 N TRP E 34  ? N TRP M 35  O TRP E 46  ? O TRP M 47  
AC4 5 6 N TYR E 48  ? N TYR M 49  O LYS E 52  ? O LYS M 53  
AC5 1 2 N MET E 11  ? N MET M 11  O LYS E 104 ? O LYS M 103 
AC5 2 3 O LEU E 105 ? O LEU M 104 N ALA E 83  ? N ALA M 84  
AC5 3 4 N SER E 91  ? N SER M 92  O MET E 96  B O MET M 95  
AC6 1 2 N PHE E 117 ? N PHE M 116 O LEU E 136 ? O LEU M 135 
AC6 2 3 N PHE E 140 ? N PHE M 139 O TYR E 174 ? O TYR M 173 
AC6 3 4 O THR E 179 ? O THR M 178 N GLN E 161 ? N GLN M 160 
AC7 1 2 O ALA E 154 ? O ALA M 153 N VAL E 151 ? N VAL M 150 
AC7 2 3 N LYS E 150 ? N LYS M 149 O ALA E 194 ? O ALA M 193 
AC7 3 4 N VAL E 197 ? N VAL M 196 O VAL E 206 ? O VAL M 205 
AC8 1 2 N GLN F 3   ? N GLN V 5   O UNK F 25  ? O UNK V 27  
AC8 2 3 N LEU F 18  ? N LEU V 20  O UNK F 83  ? O UNK V 85  
AC8 3 4 O UNK F 80  ? O UNK V 82  N SER F 71  ? N SER V 73  
AC9 1 2 N GLY F 10  ? N GLY V 12  O THR F 118 ? O THR V 120 
AC9 2 3 O THR F 115 ? O THR V 117 N TYR F 94  ? N TYR V 96  
AC9 3 4 O UNK F 93  ? O UNK V 95  N GLN F 39  ? N GLN V 41  
AC9 4 5 N ARG F 38  ? N ARG V 40  O GLU F 46  ? O GLU V 48  
AC9 5 6 N UNK F 50  ? N UNK V 52  O UNK F 59  ? O UNK V 61  
AD1 1 2 N GLY F 10  ? N GLY V 12  O THR F 118 ? O THR V 120 
AD1 2 3 O THR F 115 ? O THR V 117 N TYR F 94  ? N TYR V 96  
AD1 3 4 N UNK F 98  ? N UNK V 100 O UNK F 110 ? O UNK V 112 
# 
_pdbx_entry_details.entry_id                   9FXT 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           
'Activation of an aberrant glycosylation pathway in cancer cells can lead to expression of the onco-foetal sialyl-Tn (sTn) antigen.' 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER H 15  ? ? 71.29   -4.13   
2  1 SER I 15  ? ? 72.19   -5.18   
3  1 TYR I 33  ? ? 70.10   150.16  
4  1 ARG I 66  ? ? -143.74 19.44   
5  1 UNK K 18  ? ? -100.90 -162.83 
6  1 UNK K 28  ? ? 75.24   -1.97   
7  1 UNK K 54  ? ? -76.42  -169.36 
8  1 UNK K 59  ? ? 65.82   -177.38 
9  1 UNK K 108 ? ? 69.85   67.32   
10 1 THR L 51  ? ? 68.87   -50.29  
11 1 ASN L 138 ? ? 57.80   71.72   
12 1 THR M 51  ? ? 69.11   -50.89  
13 1 ASN M 138 ? ? 58.01   71.22   
14 1 UNK V 18  ? ? -93.05  -138.85 
15 1 UNK V 28  ? ? 69.49   -2.53   
16 1 UNK V 57  ? ? 79.13   -3.47   
17 1 UNK V 59  ? ? 72.91   178.80  
18 1 UNK V 108 ? ? 82.29   59.47   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ASP 
_pdbx_validate_peptide_omega.auth_asym_id_1   L 
_pdbx_validate_peptide_omega.auth_seq_id_1    94 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   L 
_pdbx_validate_peptide_omega.auth_seq_id_2    95 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            148.26 
# 
_pdbx_molecule_features.prd_id    PRD_002573 
_pdbx_molecule_features.name      Sialyl-Tn-Ser 
_pdbx_molecule_features.type      Oligosaccharide 
_pdbx_molecule_features.class     Antigen 
_pdbx_molecule_features.details   
;Sialyl-Tn (sTn) antigen is a truncated O-glycan containing a sialic acid alpha-2,6 linked to N-acetylgalactosamine (GalNAc) alpha-O-serine or to N-acetylgalactosamine (GalNAc) alpha-O-threonine.
;
# 
loop_
_pdbx_molecule.instance_id 
_pdbx_molecule.prd_id 
_pdbx_molecule.asym_id 
1 PRD_002573 G 
1 PRD_002573 L 
2 PRD_002573 H 
2 PRD_002573 I 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      V 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       315 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.76 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H GLU 1   ? A GLU 1   
2  1 Y 1 H ILE 25  ? A ILE 25  
3  1 Y 1 H SER 31  ? A SER 31  
4  1 Y 1 H GLY 32  ? A GLY 32  
5  1 Y 1 H TYR 33  ? A TYR 33  
6  1 Y 1 H TYR 53  ? A TYR 54  
7  1 Y 1 H ASP 54  ? A ASP 55  
8  1 Y 1 H GLY 55  ? A GLY 56  
9  1 Y 1 H SER 56  ? A SER 57  
10 1 Y 1 H ASN 57  ? A ASN 58  
11 1 Y 1 H ILE 58  ? A ILE 59  
12 1 Y 1 H SER 68  ? A SER 69  
13 1 Y 1 H LYS 129 ? A LYS 129 
14 1 Y 1 H SER 130 ? A SER 130 
15 1 Y 1 H THR 131 ? A THR 131 
16 1 Y 1 H SER 132 ? A SER 132 
17 1 Y 1 H SER 215 ? A SER 215 
18 1 Y 1 H CYS 216 ? A CYS 216 
19 1 Y 1 K SER 123 ? C SER 121 
20 1 Y 1 K HIS 124 ? C HIS 122 
21 1 Y 1 K HIS 125 ? C HIS 123 
22 1 Y 1 K HIS 126 ? C HIS 124 
23 1 Y 1 K HIS 127 ? C HIS 125 
24 1 Y 1 K HIS 128 ? C HIS 126 
25 1 Y 1 K HIS 129 ? C HIS 127 
26 1 Y 1 L CYS 214 ? D CYS 215 
27 1 Y 1 M ASP 1   ? E ASP 1   
28 1 Y 1 M ILE 2   ? E ILE 2   
29 1 Y 1 M VAL 3   ? E VAL 3   
30 1 Y 1 M SER 27  ? E SER 26  
31 1 Y 1 M SER 28  ? E SER 27  
32 1 Y 1 M SER 29  ? E SER 28  
33 1 Y 1 M VAL 30  ? E VAL 29  
34 1 Y 1 M SER 31  ? E SER 30  
35 1 Y 1 M TYR 32  ? E TYR 31  
36 1 Y 1 M ASP 94  ? E ASP 93  
37 1 Y 1 M CYS 214 ? E CYS 215 
38 1 Y 1 V SER 122 ? F SER 120 
39 1 Y 1 V SER 123 ? F SER 121 
40 1 Y 1 V HIS 124 ? F HIS 122 
41 1 Y 1 V HIS 125 ? F HIS 123 
42 1 Y 1 V HIS 126 ? F HIS 124 
43 1 Y 1 V HIS 127 ? F HIS 125 
44 1 Y 1 V HIS 128 ? F HIS 126 
45 1 Y 1 V HIS 129 ? F HIS 127 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A2G O5   O N N 1   
A2G C1   C N S 2   
A2G O1   O N N 3   
A2G C2   C N R 4   
A2G N2   N N N 5   
A2G C3   C N R 6   
A2G O3   O N N 7   
A2G C4   C N R 8   
A2G O4   O N N 9   
A2G C5   C N R 10  
A2G C6   C N N 11  
A2G O6   O N N 12  
A2G C7   C N N 13  
A2G O7   O N N 14  
A2G C8   C N N 15  
A2G H1   H N N 16  
A2G HO1  H N N 17  
A2G H2   H N N 18  
A2G HN2  H N N 19  
A2G H3   H N N 20  
A2G HO3  H N N 21  
A2G H4   H N N 22  
A2G HO4  H N N 23  
A2G H5   H N N 24  
A2G H61  H N N 25  
A2G H81  H N N 26  
A2G H82  H N N 27  
A2G H83  H N N 28  
A2G H62  H N N 29  
A2G HO6  H N N 30  
ALA N    N N N 31  
ALA CA   C N S 32  
ALA C    C N N 33  
ALA O    O N N 34  
ALA CB   C N N 35  
ALA OXT  O N N 36  
ALA H    H N N 37  
ALA H2   H N N 38  
ALA HA   H N N 39  
ALA HB1  H N N 40  
ALA HB2  H N N 41  
ALA HB3  H N N 42  
ALA HXT  H N N 43  
ARG N    N N N 44  
ARG CA   C N S 45  
ARG C    C N N 46  
ARG O    O N N 47  
ARG CB   C N N 48  
ARG CG   C N N 49  
ARG CD   C N N 50  
ARG NE   N N N 51  
ARG CZ   C N N 52  
ARG NH1  N N N 53  
ARG NH2  N N N 54  
ARG OXT  O N N 55  
ARG H    H N N 56  
ARG H2   H N N 57  
ARG HA   H N N 58  
ARG HB2  H N N 59  
ARG HB3  H N N 60  
ARG HG2  H N N 61  
ARG HG3  H N N 62  
ARG HD2  H N N 63  
ARG HD3  H N N 64  
ARG HE   H N N 65  
ARG HH11 H N N 66  
ARG HH12 H N N 67  
ARG HH21 H N N 68  
ARG HH22 H N N 69  
ARG HXT  H N N 70  
ASN N    N N N 71  
ASN CA   C N S 72  
ASN C    C N N 73  
ASN O    O N N 74  
ASN CB   C N N 75  
ASN CG   C N N 76  
ASN OD1  O N N 77  
ASN ND2  N N N 78  
ASN OXT  O N N 79  
ASN H    H N N 80  
ASN H2   H N N 81  
ASN HA   H N N 82  
ASN HB2  H N N 83  
ASN HB3  H N N 84  
ASN HD21 H N N 85  
ASN HD22 H N N 86  
ASN HXT  H N N 87  
ASP N    N N N 88  
ASP CA   C N S 89  
ASP C    C N N 90  
ASP O    O N N 91  
ASP CB   C N N 92  
ASP CG   C N N 93  
ASP OD1  O N N 94  
ASP OD2  O N N 95  
ASP OXT  O N N 96  
ASP H    H N N 97  
ASP H2   H N N 98  
ASP HA   H N N 99  
ASP HB2  H N N 100 
ASP HB3  H N N 101 
ASP HD2  H N N 102 
ASP HXT  H N N 103 
CYS N    N N N 104 
CYS CA   C N R 105 
CYS C    C N N 106 
CYS O    O N N 107 
CYS CB   C N N 108 
CYS SG   S N N 109 
CYS OXT  O N N 110 
CYS H    H N N 111 
CYS H2   H N N 112 
CYS HA   H N N 113 
CYS HB2  H N N 114 
CYS HB3  H N N 115 
CYS HG   H N N 116 
CYS HXT  H N N 117 
GLN N    N N N 118 
GLN CA   C N S 119 
GLN C    C N N 120 
GLN O    O N N 121 
GLN CB   C N N 122 
GLN CG   C N N 123 
GLN CD   C N N 124 
GLN OE1  O N N 125 
GLN NE2  N N N 126 
GLN OXT  O N N 127 
GLN H    H N N 128 
GLN H2   H N N 129 
GLN HA   H N N 130 
GLN HB2  H N N 131 
GLN HB3  H N N 132 
GLN HG2  H N N 133 
GLN HG3  H N N 134 
GLN HE21 H N N 135 
GLN HE22 H N N 136 
GLN HXT  H N N 137 
GLU N    N N N 138 
GLU CA   C N S 139 
GLU C    C N N 140 
GLU O    O N N 141 
GLU CB   C N N 142 
GLU CG   C N N 143 
GLU CD   C N N 144 
GLU OE1  O N N 145 
GLU OE2  O N N 146 
GLU OXT  O N N 147 
GLU H    H N N 148 
GLU H2   H N N 149 
GLU HA   H N N 150 
GLU HB2  H N N 151 
GLU HB3  H N N 152 
GLU HG2  H N N 153 
GLU HG3  H N N 154 
GLU HE2  H N N 155 
GLU HXT  H N N 156 
GLY N    N N N 157 
GLY CA   C N N 158 
GLY C    C N N 159 
GLY O    O N N 160 
GLY OXT  O N N 161 
GLY H    H N N 162 
GLY H2   H N N 163 
GLY HA2  H N N 164 
GLY HA3  H N N 165 
GLY HXT  H N N 166 
GOL C1   C N N 167 
GOL O1   O N N 168 
GOL C2   C N N 169 
GOL O2   O N N 170 
GOL C3   C N N 171 
GOL O3   O N N 172 
GOL H11  H N N 173 
GOL H12  H N N 174 
GOL HO1  H N N 175 
GOL H2   H N N 176 
GOL HO2  H N N 177 
GOL H31  H N N 178 
GOL H32  H N N 179 
GOL HO3  H N N 180 
HIS N    N N N 181 
HIS CA   C N S 182 
HIS C    C N N 183 
HIS O    O N N 184 
HIS CB   C N N 185 
HIS CG   C Y N 186 
HIS ND1  N Y N 187 
HIS CD2  C Y N 188 
HIS CE1  C Y N 189 
HIS NE2  N Y N 190 
HIS OXT  O N N 191 
HIS H    H N N 192 
HIS H2   H N N 193 
HIS HA   H N N 194 
HIS HB2  H N N 195 
HIS HB3  H N N 196 
HIS HD1  H N N 197 
HIS HD2  H N N 198 
HIS HE1  H N N 199 
HIS HE2  H N N 200 
HIS HXT  H N N 201 
HOH O    O N N 202 
HOH H1   H N N 203 
HOH H2   H N N 204 
ILE N    N N N 205 
ILE CA   C N S 206 
ILE C    C N N 207 
ILE O    O N N 208 
ILE CB   C N S 209 
ILE CG1  C N N 210 
ILE CG2  C N N 211 
ILE CD1  C N N 212 
ILE OXT  O N N 213 
ILE H    H N N 214 
ILE H2   H N N 215 
ILE HA   H N N 216 
ILE HB   H N N 217 
ILE HG12 H N N 218 
ILE HG13 H N N 219 
ILE HG21 H N N 220 
ILE HG22 H N N 221 
ILE HG23 H N N 222 
ILE HD11 H N N 223 
ILE HD12 H N N 224 
ILE HD13 H N N 225 
ILE HXT  H N N 226 
LEU N    N N N 227 
LEU CA   C N S 228 
LEU C    C N N 229 
LEU O    O N N 230 
LEU CB   C N N 231 
LEU CG   C N N 232 
LEU CD1  C N N 233 
LEU CD2  C N N 234 
LEU OXT  O N N 235 
LEU H    H N N 236 
LEU H2   H N N 237 
LEU HA   H N N 238 
LEU HB2  H N N 239 
LEU HB3  H N N 240 
LEU HG   H N N 241 
LEU HD11 H N N 242 
LEU HD12 H N N 243 
LEU HD13 H N N 244 
LEU HD21 H N N 245 
LEU HD22 H N N 246 
LEU HD23 H N N 247 
LEU HXT  H N N 248 
LYS N    N N N 249 
LYS CA   C N S 250 
LYS C    C N N 251 
LYS O    O N N 252 
LYS CB   C N N 253 
LYS CG   C N N 254 
LYS CD   C N N 255 
LYS CE   C N N 256 
LYS NZ   N N N 257 
LYS OXT  O N N 258 
LYS H    H N N 259 
LYS H2   H N N 260 
LYS HA   H N N 261 
LYS HB2  H N N 262 
LYS HB3  H N N 263 
LYS HG2  H N N 264 
LYS HG3  H N N 265 
LYS HD2  H N N 266 
LYS HD3  H N N 267 
LYS HE2  H N N 268 
LYS HE3  H N N 269 
LYS HZ1  H N N 270 
LYS HZ2  H N N 271 
LYS HZ3  H N N 272 
LYS HXT  H N N 273 
MET N    N N N 274 
MET CA   C N S 275 
MET C    C N N 276 
MET O    O N N 277 
MET CB   C N N 278 
MET CG   C N N 279 
MET SD   S N N 280 
MET CE   C N N 281 
MET OXT  O N N 282 
MET H    H N N 283 
MET H2   H N N 284 
MET HA   H N N 285 
MET HB2  H N N 286 
MET HB3  H N N 287 
MET HG2  H N N 288 
MET HG3  H N N 289 
MET HE1  H N N 290 
MET HE2  H N N 291 
MET HE3  H N N 292 
MET HXT  H N N 293 
PEG C1   C N N 294 
PEG O1   O N N 295 
PEG C2   C N N 296 
PEG O2   O N N 297 
PEG C3   C N N 298 
PEG C4   C N N 299 
PEG O4   O N N 300 
PEG H11  H N N 301 
PEG H12  H N N 302 
PEG HO1  H N N 303 
PEG H21  H N N 304 
PEG H22  H N N 305 
PEG H31  H N N 306 
PEG H32  H N N 307 
PEG H41  H N N 308 
PEG H42  H N N 309 
PEG HO4  H N N 310 
PHE N    N N N 311 
PHE CA   C N S 312 
PHE C    C N N 313 
PHE O    O N N 314 
PHE CB   C N N 315 
PHE CG   C Y N 316 
PHE CD1  C Y N 317 
PHE CD2  C Y N 318 
PHE CE1  C Y N 319 
PHE CE2  C Y N 320 
PHE CZ   C Y N 321 
PHE OXT  O N N 322 
PHE H    H N N 323 
PHE H2   H N N 324 
PHE HA   H N N 325 
PHE HB2  H N N 326 
PHE HB3  H N N 327 
PHE HD1  H N N 328 
PHE HD2  H N N 329 
PHE HE1  H N N 330 
PHE HE2  H N N 331 
PHE HZ   H N N 332 
PHE HXT  H N N 333 
PRO N    N N N 334 
PRO CA   C N S 335 
PRO C    C N N 336 
PRO O    O N N 337 
PRO CB   C N N 338 
PRO CG   C N N 339 
PRO CD   C N N 340 
PRO OXT  O N N 341 
PRO H    H N N 342 
PRO HA   H N N 343 
PRO HB2  H N N 344 
PRO HB3  H N N 345 
PRO HG2  H N N 346 
PRO HG3  H N N 347 
PRO HD2  H N N 348 
PRO HD3  H N N 349 
PRO HXT  H N N 350 
SER N    N N N 351 
SER CA   C N S 352 
SER C    C N N 353 
SER O    O N N 354 
SER CB   C N N 355 
SER OG   O N N 356 
SER OXT  O N N 357 
SER H    H N N 358 
SER H2   H N N 359 
SER HA   H N N 360 
SER HB2  H N N 361 
SER HB3  H N N 362 
SER HG   H N N 363 
SER HXT  H N N 364 
SIA C1   C N N 365 
SIA C2   C N R 366 
SIA C3   C N N 367 
SIA C4   C N S 368 
SIA C5   C N R 369 
SIA C6   C N R 370 
SIA C7   C N R 371 
SIA C8   C N R 372 
SIA C9   C N N 373 
SIA C10  C N N 374 
SIA C11  C N N 375 
SIA N5   N N N 376 
SIA O1A  O N N 377 
SIA O1B  O N N 378 
SIA O2   O N N 379 
SIA O4   O N N 380 
SIA O6   O N N 381 
SIA O7   O N N 382 
SIA O8   O N N 383 
SIA O9   O N N 384 
SIA O10  O N N 385 
SIA H32  H N N 386 
SIA H31  H N N 387 
SIA H4   H N N 388 
SIA H5   H N N 389 
SIA H6   H N N 390 
SIA H7   H N N 391 
SIA H8   H N N 392 
SIA H92  H N N 393 
SIA H91  H N N 394 
SIA H111 H N N 395 
SIA H113 H N N 396 
SIA H112 H N N 397 
SIA HN5  H N N 398 
SIA HO1B H N N 399 
SIA HO2  H N N 400 
SIA HO4  H N N 401 
SIA HO7  H N N 402 
SIA HO8  H N N 403 
SIA HO9  H N N 404 
THR N    N N N 405 
THR CA   C N S 406 
THR C    C N N 407 
THR O    O N N 408 
THR CB   C N R 409 
THR OG1  O N N 410 
THR CG2  C N N 411 
THR OXT  O N N 412 
THR H    H N N 413 
THR H2   H N N 414 
THR HA   H N N 415 
THR HB   H N N 416 
THR HG1  H N N 417 
THR HG21 H N N 418 
THR HG22 H N N 419 
THR HG23 H N N 420 
THR HXT  H N N 421 
TRP N    N N N 422 
TRP CA   C N S 423 
TRP C    C N N 424 
TRP O    O N N 425 
TRP CB   C N N 426 
TRP CG   C Y N 427 
TRP CD1  C Y N 428 
TRP CD2  C Y N 429 
TRP NE1  N Y N 430 
TRP CE2  C Y N 431 
TRP CE3  C Y N 432 
TRP CZ2  C Y N 433 
TRP CZ3  C Y N 434 
TRP CH2  C Y N 435 
TRP OXT  O N N 436 
TRP H    H N N 437 
TRP H2   H N N 438 
TRP HA   H N N 439 
TRP HB2  H N N 440 
TRP HB3  H N N 441 
TRP HD1  H N N 442 
TRP HE1  H N N 443 
TRP HE3  H N N 444 
TRP HZ2  H N N 445 
TRP HZ3  H N N 446 
TRP HH2  H N N 447 
TRP HXT  H N N 448 
TYR N    N N N 449 
TYR CA   C N S 450 
TYR C    C N N 451 
TYR O    O N N 452 
TYR CB   C N N 453 
TYR CG   C Y N 454 
TYR CD1  C Y N 455 
TYR CD2  C Y N 456 
TYR CE1  C Y N 457 
TYR CE2  C Y N 458 
TYR CZ   C Y N 459 
TYR OH   O N N 460 
TYR OXT  O N N 461 
TYR H    H N N 462 
TYR H2   H N N 463 
TYR HA   H N N 464 
TYR HB2  H N N 465 
TYR HB3  H N N 466 
TYR HD1  H N N 467 
TYR HD2  H N N 468 
TYR HE1  H N N 469 
TYR HE2  H N N 470 
TYR HH   H N N 471 
TYR HXT  H N N 472 
VAL N    N N N 473 
VAL CA   C N S 474 
VAL C    C N N 475 
VAL O    O N N 476 
VAL CB   C N N 477 
VAL CG1  C N N 478 
VAL CG2  C N N 479 
VAL OXT  O N N 480 
VAL H    H N N 481 
VAL H2   H N N 482 
VAL HA   H N N 483 
VAL HB   H N N 484 
VAL HG11 H N N 485 
VAL HG12 H N N 486 
VAL HG13 H N N 487 
VAL HG21 H N N 488 
VAL HG22 H N N 489 
VAL HG23 H N N 490 
VAL HXT  H N N 491 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A2G O5  C5   sing N N 1   
A2G C1  O5   sing N N 2   
A2G C1  C2   sing N N 3   
A2G C1  H1   sing N N 4   
A2G O1  C1   sing N N 5   
A2G O1  HO1  sing N N 6   
A2G C2  C3   sing N N 7   
A2G C2  H2   sing N N 8   
A2G N2  C2   sing N N 9   
A2G N2  HN2  sing N N 10  
A2G C3  C4   sing N N 11  
A2G C3  O3   sing N N 12  
A2G C3  H3   sing N N 13  
A2G O3  HO3  sing N N 14  
A2G C4  O4   sing N N 15  
A2G C4  H4   sing N N 16  
A2G O4  HO4  sing N N 17  
A2G C5  C4   sing N N 18  
A2G C5  C6   sing N N 19  
A2G C5  H5   sing N N 20  
A2G C6  O6   sing N N 21  
A2G C6  H61  sing N N 22  
A2G C7  N2   sing N N 23  
A2G O7  C7   doub N N 24  
A2G C8  C7   sing N N 25  
A2G C8  H81  sing N N 26  
A2G C8  H82  sing N N 27  
A2G C8  H83  sing N N 28  
A2G C6  H62  sing N N 29  
A2G O6  HO6  sing N N 30  
ALA N   CA   sing N N 31  
ALA N   H    sing N N 32  
ALA N   H2   sing N N 33  
ALA CA  C    sing N N 34  
ALA CA  CB   sing N N 35  
ALA CA  HA   sing N N 36  
ALA C   O    doub N N 37  
ALA C   OXT  sing N N 38  
ALA CB  HB1  sing N N 39  
ALA CB  HB2  sing N N 40  
ALA CB  HB3  sing N N 41  
ALA OXT HXT  sing N N 42  
ARG N   CA   sing N N 43  
ARG N   H    sing N N 44  
ARG N   H2   sing N N 45  
ARG CA  C    sing N N 46  
ARG CA  CB   sing N N 47  
ARG CA  HA   sing N N 48  
ARG C   O    doub N N 49  
ARG C   OXT  sing N N 50  
ARG CB  CG   sing N N 51  
ARG CB  HB2  sing N N 52  
ARG CB  HB3  sing N N 53  
ARG CG  CD   sing N N 54  
ARG CG  HG2  sing N N 55  
ARG CG  HG3  sing N N 56  
ARG CD  NE   sing N N 57  
ARG CD  HD2  sing N N 58  
ARG CD  HD3  sing N N 59  
ARG NE  CZ   sing N N 60  
ARG NE  HE   sing N N 61  
ARG CZ  NH1  sing N N 62  
ARG CZ  NH2  doub N N 63  
ARG NH1 HH11 sing N N 64  
ARG NH1 HH12 sing N N 65  
ARG NH2 HH21 sing N N 66  
ARG NH2 HH22 sing N N 67  
ARG OXT HXT  sing N N 68  
ASN N   CA   sing N N 69  
ASN N   H    sing N N 70  
ASN N   H2   sing N N 71  
ASN CA  C    sing N N 72  
ASN CA  CB   sing N N 73  
ASN CA  HA   sing N N 74  
ASN C   O    doub N N 75  
ASN C   OXT  sing N N 76  
ASN CB  CG   sing N N 77  
ASN CB  HB2  sing N N 78  
ASN CB  HB3  sing N N 79  
ASN CG  OD1  doub N N 80  
ASN CG  ND2  sing N N 81  
ASN ND2 HD21 sing N N 82  
ASN ND2 HD22 sing N N 83  
ASN OXT HXT  sing N N 84  
ASP N   CA   sing N N 85  
ASP N   H    sing N N 86  
ASP N   H2   sing N N 87  
ASP CA  C    sing N N 88  
ASP CA  CB   sing N N 89  
ASP CA  HA   sing N N 90  
ASP C   O    doub N N 91  
ASP C   OXT  sing N N 92  
ASP CB  CG   sing N N 93  
ASP CB  HB2  sing N N 94  
ASP CB  HB3  sing N N 95  
ASP CG  OD1  doub N N 96  
ASP CG  OD2  sing N N 97  
ASP OD2 HD2  sing N N 98  
ASP OXT HXT  sing N N 99  
CYS N   CA   sing N N 100 
CYS N   H    sing N N 101 
CYS N   H2   sing N N 102 
CYS CA  C    sing N N 103 
CYS CA  CB   sing N N 104 
CYS CA  HA   sing N N 105 
CYS C   O    doub N N 106 
CYS C   OXT  sing N N 107 
CYS CB  SG   sing N N 108 
CYS CB  HB2  sing N N 109 
CYS CB  HB3  sing N N 110 
CYS SG  HG   sing N N 111 
CYS OXT HXT  sing N N 112 
GLN N   CA   sing N N 113 
GLN N   H    sing N N 114 
GLN N   H2   sing N N 115 
GLN CA  C    sing N N 116 
GLN CA  CB   sing N N 117 
GLN CA  HA   sing N N 118 
GLN C   O    doub N N 119 
GLN C   OXT  sing N N 120 
GLN CB  CG   sing N N 121 
GLN CB  HB2  sing N N 122 
GLN CB  HB3  sing N N 123 
GLN CG  CD   sing N N 124 
GLN CG  HG2  sing N N 125 
GLN CG  HG3  sing N N 126 
GLN CD  OE1  doub N N 127 
GLN CD  NE2  sing N N 128 
GLN NE2 HE21 sing N N 129 
GLN NE2 HE22 sing N N 130 
GLN OXT HXT  sing N N 131 
GLU N   CA   sing N N 132 
GLU N   H    sing N N 133 
GLU N   H2   sing N N 134 
GLU CA  C    sing N N 135 
GLU CA  CB   sing N N 136 
GLU CA  HA   sing N N 137 
GLU C   O    doub N N 138 
GLU C   OXT  sing N N 139 
GLU CB  CG   sing N N 140 
GLU CB  HB2  sing N N 141 
GLU CB  HB3  sing N N 142 
GLU CG  CD   sing N N 143 
GLU CG  HG2  sing N N 144 
GLU CG  HG3  sing N N 145 
GLU CD  OE1  doub N N 146 
GLU CD  OE2  sing N N 147 
GLU OE2 HE2  sing N N 148 
GLU OXT HXT  sing N N 149 
GLY N   CA   sing N N 150 
GLY N   H    sing N N 151 
GLY N   H2   sing N N 152 
GLY CA  C    sing N N 153 
GLY CA  HA2  sing N N 154 
GLY CA  HA3  sing N N 155 
GLY C   O    doub N N 156 
GLY C   OXT  sing N N 157 
GLY OXT HXT  sing N N 158 
GOL C1  O1   sing N N 159 
GOL C1  C2   sing N N 160 
GOL C1  H11  sing N N 161 
GOL C1  H12  sing N N 162 
GOL O1  HO1  sing N N 163 
GOL C2  O2   sing N N 164 
GOL C2  C3   sing N N 165 
GOL C2  H2   sing N N 166 
GOL O2  HO2  sing N N 167 
GOL C3  O3   sing N N 168 
GOL C3  H31  sing N N 169 
GOL C3  H32  sing N N 170 
GOL O3  HO3  sing N N 171 
HIS N   CA   sing N N 172 
HIS N   H    sing N N 173 
HIS N   H2   sing N N 174 
HIS CA  C    sing N N 175 
HIS CA  CB   sing N N 176 
HIS CA  HA   sing N N 177 
HIS C   O    doub N N 178 
HIS C   OXT  sing N N 179 
HIS CB  CG   sing N N 180 
HIS CB  HB2  sing N N 181 
HIS CB  HB3  sing N N 182 
HIS CG  ND1  sing Y N 183 
HIS CG  CD2  doub Y N 184 
HIS ND1 CE1  doub Y N 185 
HIS ND1 HD1  sing N N 186 
HIS CD2 NE2  sing Y N 187 
HIS CD2 HD2  sing N N 188 
HIS CE1 NE2  sing Y N 189 
HIS CE1 HE1  sing N N 190 
HIS NE2 HE2  sing N N 191 
HIS OXT HXT  sing N N 192 
HOH O   H1   sing N N 193 
HOH O   H2   sing N N 194 
ILE N   CA   sing N N 195 
ILE N   H    sing N N 196 
ILE N   H2   sing N N 197 
ILE CA  C    sing N N 198 
ILE CA  CB   sing N N 199 
ILE CA  HA   sing N N 200 
ILE C   O    doub N N 201 
ILE C   OXT  sing N N 202 
ILE CB  CG1  sing N N 203 
ILE CB  CG2  sing N N 204 
ILE CB  HB   sing N N 205 
ILE CG1 CD1  sing N N 206 
ILE CG1 HG12 sing N N 207 
ILE CG1 HG13 sing N N 208 
ILE CG2 HG21 sing N N 209 
ILE CG2 HG22 sing N N 210 
ILE CG2 HG23 sing N N 211 
ILE CD1 HD11 sing N N 212 
ILE CD1 HD12 sing N N 213 
ILE CD1 HD13 sing N N 214 
ILE OXT HXT  sing N N 215 
LEU N   CA   sing N N 216 
LEU N   H    sing N N 217 
LEU N   H2   sing N N 218 
LEU CA  C    sing N N 219 
LEU CA  CB   sing N N 220 
LEU CA  HA   sing N N 221 
LEU C   O    doub N N 222 
LEU C   OXT  sing N N 223 
LEU CB  CG   sing N N 224 
LEU CB  HB2  sing N N 225 
LEU CB  HB3  sing N N 226 
LEU CG  CD1  sing N N 227 
LEU CG  CD2  sing N N 228 
LEU CG  HG   sing N N 229 
LEU CD1 HD11 sing N N 230 
LEU CD1 HD12 sing N N 231 
LEU CD1 HD13 sing N N 232 
LEU CD2 HD21 sing N N 233 
LEU CD2 HD22 sing N N 234 
LEU CD2 HD23 sing N N 235 
LEU OXT HXT  sing N N 236 
LYS N   CA   sing N N 237 
LYS N   H    sing N N 238 
LYS N   H2   sing N N 239 
LYS CA  C    sing N N 240 
LYS CA  CB   sing N N 241 
LYS CA  HA   sing N N 242 
LYS C   O    doub N N 243 
LYS C   OXT  sing N N 244 
LYS CB  CG   sing N N 245 
LYS CB  HB2  sing N N 246 
LYS CB  HB3  sing N N 247 
LYS CG  CD   sing N N 248 
LYS CG  HG2  sing N N 249 
LYS CG  HG3  sing N N 250 
LYS CD  CE   sing N N 251 
LYS CD  HD2  sing N N 252 
LYS CD  HD3  sing N N 253 
LYS CE  NZ   sing N N 254 
LYS CE  HE2  sing N N 255 
LYS CE  HE3  sing N N 256 
LYS NZ  HZ1  sing N N 257 
LYS NZ  HZ2  sing N N 258 
LYS NZ  HZ3  sing N N 259 
LYS OXT HXT  sing N N 260 
MET N   CA   sing N N 261 
MET N   H    sing N N 262 
MET N   H2   sing N N 263 
MET CA  C    sing N N 264 
MET CA  CB   sing N N 265 
MET CA  HA   sing N N 266 
MET C   O    doub N N 267 
MET C   OXT  sing N N 268 
MET CB  CG   sing N N 269 
MET CB  HB2  sing N N 270 
MET CB  HB3  sing N N 271 
MET CG  SD   sing N N 272 
MET CG  HG2  sing N N 273 
MET CG  HG3  sing N N 274 
MET SD  CE   sing N N 275 
MET CE  HE1  sing N N 276 
MET CE  HE2  sing N N 277 
MET CE  HE3  sing N N 278 
MET OXT HXT  sing N N 279 
PEG C1  O1   sing N N 280 
PEG C1  C2   sing N N 281 
PEG C1  H11  sing N N 282 
PEG C1  H12  sing N N 283 
PEG O1  HO1  sing N N 284 
PEG C2  O2   sing N N 285 
PEG C2  H21  sing N N 286 
PEG C2  H22  sing N N 287 
PEG O2  C3   sing N N 288 
PEG C3  C4   sing N N 289 
PEG C3  H31  sing N N 290 
PEG C3  H32  sing N N 291 
PEG C4  O4   sing N N 292 
PEG C4  H41  sing N N 293 
PEG C4  H42  sing N N 294 
PEG O4  HO4  sing N N 295 
PHE N   CA   sing N N 296 
PHE N   H    sing N N 297 
PHE N   H2   sing N N 298 
PHE CA  C    sing N N 299 
PHE CA  CB   sing N N 300 
PHE CA  HA   sing N N 301 
PHE C   O    doub N N 302 
PHE C   OXT  sing N N 303 
PHE CB  CG   sing N N 304 
PHE CB  HB2  sing N N 305 
PHE CB  HB3  sing N N 306 
PHE CG  CD1  doub Y N 307 
PHE CG  CD2  sing Y N 308 
PHE CD1 CE1  sing Y N 309 
PHE CD1 HD1  sing N N 310 
PHE CD2 CE2  doub Y N 311 
PHE CD2 HD2  sing N N 312 
PHE CE1 CZ   doub Y N 313 
PHE CE1 HE1  sing N N 314 
PHE CE2 CZ   sing Y N 315 
PHE CE2 HE2  sing N N 316 
PHE CZ  HZ   sing N N 317 
PHE OXT HXT  sing N N 318 
PRO N   CA   sing N N 319 
PRO N   CD   sing N N 320 
PRO N   H    sing N N 321 
PRO CA  C    sing N N 322 
PRO CA  CB   sing N N 323 
PRO CA  HA   sing N N 324 
PRO C   O    doub N N 325 
PRO C   OXT  sing N N 326 
PRO CB  CG   sing N N 327 
PRO CB  HB2  sing N N 328 
PRO CB  HB3  sing N N 329 
PRO CG  CD   sing N N 330 
PRO CG  HG2  sing N N 331 
PRO CG  HG3  sing N N 332 
PRO CD  HD2  sing N N 333 
PRO CD  HD3  sing N N 334 
PRO OXT HXT  sing N N 335 
SER N   CA   sing N N 336 
SER N   H    sing N N 337 
SER N   H2   sing N N 338 
SER CA  C    sing N N 339 
SER CA  CB   sing N N 340 
SER CA  HA   sing N N 341 
SER C   O    doub N N 342 
SER C   OXT  sing N N 343 
SER CB  OG   sing N N 344 
SER CB  HB2  sing N N 345 
SER CB  HB3  sing N N 346 
SER OG  HG   sing N N 347 
SER OXT HXT  sing N N 348 
SIA C1  C2   sing N N 349 
SIA C1  O1A  doub N N 350 
SIA C1  O1B  sing N N 351 
SIA C2  C3   sing N N 352 
SIA C2  O2   sing N N 353 
SIA C2  O6   sing N N 354 
SIA C3  C4   sing N N 355 
SIA C3  H32  sing N N 356 
SIA C3  H31  sing N N 357 
SIA C4  C5   sing N N 358 
SIA C4  O4   sing N N 359 
SIA C4  H4   sing N N 360 
SIA C5  C6   sing N N 361 
SIA C5  N5   sing N N 362 
SIA C5  H5   sing N N 363 
SIA C6  C7   sing N N 364 
SIA C6  O6   sing N N 365 
SIA C6  H6   sing N N 366 
SIA C7  C8   sing N N 367 
SIA C7  O7   sing N N 368 
SIA C7  H7   sing N N 369 
SIA C8  C9   sing N N 370 
SIA C8  O8   sing N N 371 
SIA C8  H8   sing N N 372 
SIA C9  O9   sing N N 373 
SIA C9  H92  sing N N 374 
SIA C9  H91  sing N N 375 
SIA C10 C11  sing N N 376 
SIA C10 N5   sing N N 377 
SIA C10 O10  doub N N 378 
SIA C11 H111 sing N N 379 
SIA C11 H113 sing N N 380 
SIA C11 H112 sing N N 381 
SIA N5  HN5  sing N N 382 
SIA O1B HO1B sing N N 383 
SIA O2  HO2  sing N N 384 
SIA O4  HO4  sing N N 385 
SIA O7  HO7  sing N N 386 
SIA O8  HO8  sing N N 387 
SIA O9  HO9  sing N N 388 
THR N   CA   sing N N 389 
THR N   H    sing N N 390 
THR N   H2   sing N N 391 
THR CA  C    sing N N 392 
THR CA  CB   sing N N 393 
THR CA  HA   sing N N 394 
THR C   O    doub N N 395 
THR C   OXT  sing N N 396 
THR CB  OG1  sing N N 397 
THR CB  CG2  sing N N 398 
THR CB  HB   sing N N 399 
THR OG1 HG1  sing N N 400 
THR CG2 HG21 sing N N 401 
THR CG2 HG22 sing N N 402 
THR CG2 HG23 sing N N 403 
THR OXT HXT  sing N N 404 
TRP N   CA   sing N N 405 
TRP N   H    sing N N 406 
TRP N   H2   sing N N 407 
TRP CA  C    sing N N 408 
TRP CA  CB   sing N N 409 
TRP CA  HA   sing N N 410 
TRP C   O    doub N N 411 
TRP C   OXT  sing N N 412 
TRP CB  CG   sing N N 413 
TRP CB  HB2  sing N N 414 
TRP CB  HB3  sing N N 415 
TRP CG  CD1  doub Y N 416 
TRP CG  CD2  sing Y N 417 
TRP CD1 NE1  sing Y N 418 
TRP CD1 HD1  sing N N 419 
TRP CD2 CE2  doub Y N 420 
TRP CD2 CE3  sing Y N 421 
TRP NE1 CE2  sing Y N 422 
TRP NE1 HE1  sing N N 423 
TRP CE2 CZ2  sing Y N 424 
TRP CE3 CZ3  doub Y N 425 
TRP CE3 HE3  sing N N 426 
TRP CZ2 CH2  doub Y N 427 
TRP CZ2 HZ2  sing N N 428 
TRP CZ3 CH2  sing Y N 429 
TRP CZ3 HZ3  sing N N 430 
TRP CH2 HH2  sing N N 431 
TRP OXT HXT  sing N N 432 
TYR N   CA   sing N N 433 
TYR N   H    sing N N 434 
TYR N   H2   sing N N 435 
TYR CA  C    sing N N 436 
TYR CA  CB   sing N N 437 
TYR CA  HA   sing N N 438 
TYR C   O    doub N N 439 
TYR C   OXT  sing N N 440 
TYR CB  CG   sing N N 441 
TYR CB  HB2  sing N N 442 
TYR CB  HB3  sing N N 443 
TYR CG  CD1  doub Y N 444 
TYR CG  CD2  sing Y N 445 
TYR CD1 CE1  sing Y N 446 
TYR CD1 HD1  sing N N 447 
TYR CD2 CE2  doub Y N 448 
TYR CD2 HD2  sing N N 449 
TYR CE1 CZ   doub Y N 450 
TYR CE1 HE1  sing N N 451 
TYR CE2 CZ   sing Y N 452 
TYR CE2 HE2  sing N N 453 
TYR CZ  OH   sing N N 454 
TYR OH  HH   sing N N 455 
TYR OXT HXT  sing N N 456 
VAL N   CA   sing N N 457 
VAL N   H    sing N N 458 
VAL N   H2   sing N N 459 
VAL CA  C    sing N N 460 
VAL CA  CB   sing N N 461 
VAL CA  HA   sing N N 462 
VAL C   O    doub N N 463 
VAL C   OXT  sing N N 464 
VAL CB  CG1  sing N N 465 
VAL CB  CG2  sing N N 466 
VAL CB  HB   sing N N 467 
VAL CG1 HG11 sing N N 468 
VAL CG1 HG12 sing N N 469 
VAL CG1 HG13 sing N N 470 
VAL CG2 HG21 sing N N 471 
VAL CG2 HG22 sing N N 472 
VAL CG2 HG23 sing N N 473 
VAL OXT HXT  sing N N 474 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Agencia Estatal de Investigacion (AEI)' Spain            ?         1 
'European Commission'                    'European Union' 101079417 2 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
4 A2G 1 n 
4 SIA 2 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7ZOZ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9FXT 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.020681 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007982 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005242 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . VAL A 1 2   ? 3.132   16.692  -46.667 1.00 87.53  ? 2   VAL H N   1 
ATOM   2    C CA  . VAL A 1 2   ? 3.012   16.770  -45.217 1.00 85.20  ? 2   VAL H CA  1 
ATOM   3    C C   . VAL A 1 2   ? 2.744   15.386  -44.639 1.00 80.64  ? 2   VAL H C   1 
ATOM   4    O O   . VAL A 1 2   ? 1.804   14.701  -45.049 1.00 78.65  ? 2   VAL H O   1 
ATOM   5    C CB  . VAL A 1 2   ? 1.909   17.757  -44.802 1.00 83.62  ? 2   VAL H CB  1 
ATOM   6    C CG1 . VAL A 1 2   ? 1.902   17.939  -43.293 1.00 81.21  ? 2   VAL H CG1 1 
ATOM   7    C CG2 . VAL A 1 2   ? 2.100   19.091  -45.509 1.00 84.17  ? 2   VAL H CG2 1 
ATOM   8    N N   . GLN A 1 3   ? 3.580   14.976  -43.688 1.00 78.87  ? 3   GLN H N   1 
ATOM   9    C CA  . GLN A 1 3   ? 3.449   13.681  -43.036 1.00 75.21  ? 3   GLN H CA  1 
ATOM   10   C C   . GLN A 1 3   ? 3.400   13.862  -41.526 1.00 77.90  ? 3   GLN H C   1 
ATOM   11   O O   . GLN A 1 3   ? 4.241   14.562  -40.952 1.00 75.23  ? 3   GLN H O   1 
ATOM   12   C CB  . GLN A 1 3   ? 4.602   12.754  -43.437 1.00 72.26  ? 3   GLN H CB  1 
ATOM   13   C CG  . GLN A 1 3   ? 4.323   11.949  -44.698 1.00 78.60  ? 3   GLN H CG  1 
ATOM   14   C CD  . GLN A 1 3   ? 5.509   11.126  -45.154 1.00 83.98  ? 3   GLN H CD  1 
ATOM   15   O OE1 . GLN A 1 3   ? 6.193   10.500  -44.346 1.00 84.10  ? 3   GLN H OE1 1 
ATOM   16   N NE2 . GLN A 1 3   ? 5.743   11.100  -46.461 1.00 81.10  ? 3   GLN H NE2 1 
ATOM   17   N N   . LEU A 1 4   ? 2.414   13.233  -40.889 1.00 75.23  ? 4   LEU H N   1 
ATOM   18   C CA  . LEU A 1 4   ? 2.258   13.250  -39.442 1.00 69.91  ? 4   LEU H CA  1 
ATOM   19   C C   . LEU A 1 4   ? 2.297   11.824  -38.912 1.00 71.02  ? 4   LEU H C   1 
ATOM   20   O O   . LEU A 1 4   ? 1.710   10.916  -39.510 1.00 73.62  ? 4   LEU H O   1 
ATOM   21   C CB  . LEU A 1 4   ? 0.944   13.927  -39.023 1.00 65.56  ? 4   LEU H CB  1 
ATOM   22   C CG  . LEU A 1 4   ? 0.776   15.424  -39.301 1.00 69.67  ? 4   LEU H CG  1 
ATOM   23   C CD1 . LEU A 1 4   ? 0.340   15.685  -40.738 1.00 74.21  ? 4   LEU H CD1 1 
ATOM   24   C CD2 . LEU A 1 4   ? -0.213  16.035  -38.322 1.00 72.82  ? 4   LEU H CD2 1 
ATOM   25   N N   . GLN A 1 5   ? 2.991   11.627  -37.793 1.00 74.18  ? 5   GLN H N   1 
ATOM   26   C CA  . GLN A 1 5   ? 3.141   10.311  -37.185 1.00 74.83  ? 5   GLN H CA  1 
ATOM   27   C C   . GLN A 1 5   ? 2.881   10.406  -35.689 1.00 76.07  ? 5   GLN H C   1 
ATOM   28   O O   . GLN A 1 5   ? 3.480   11.242  -35.006 1.00 77.42  ? 5   GLN H O   1 
ATOM   29   C CB  . GLN A 1 5   ? 4.539   9.739   -37.442 1.00 74.33  ? 5   GLN H CB  1 
ATOM   30   C CG  . GLN A 1 5   ? 4.751   8.346   -36.872 1.00 74.81  ? 5   GLN H CG  1 
ATOM   31   C CD  . GLN A 1 5   ? 6.153   7.825   -37.110 1.00 82.79  ? 5   GLN H CD  1 
ATOM   32   O OE1 . GLN A 1 5   ? 6.344   6.787   -37.742 1.00 85.95  ? 5   GLN H OE1 1 
ATOM   33   N NE2 . GLN A 1 5   ? 7.145   8.543   -36.597 1.00 79.28  ? 5   GLN H NE2 1 
ATOM   34   N N   . GLU A 1 6   ? 1.999   9.549   -35.186 1.00 74.44  ? 6   GLU H N   1 
ATOM   35   C CA  . GLU A 1 6   ? 1.718   9.476   -33.760 1.00 70.87  ? 6   GLU H CA  1 
ATOM   36   C C   . GLU A 1 6   ? 2.655   8.485   -33.081 1.00 66.88  ? 6   GLU H C   1 
ATOM   37   O O   . GLU A 1 6   ? 3.094   7.500   -33.681 1.00 68.73  ? 6   GLU H O   1 
ATOM   38   C CB  . GLU A 1 6   ? 0.266   9.065   -33.504 1.00 63.90  ? 6   GLU H CB  1 
ATOM   39   C CG  . GLU A 1 6   ? -0.768  10.013  -34.083 1.00 60.53  ? 6   GLU H CG  1 
ATOM   40   C CD  . GLU A 1 6   ? -1.124  9.682   -35.517 1.00 61.69  ? 6   GLU H CD  1 
ATOM   41   O OE1 . GLU A 1 6   ? -0.475  8.789   -36.102 1.00 64.99  ? 6   GLU H OE1 1 
ATOM   42   O OE2 . GLU A 1 6   ? -2.055  10.312  -36.062 1.00 60.50  ? 6   GLU H OE2 1 
ATOM   43   N N   . SER A 1 7   ? 2.961   8.760   -31.814 1.00 69.23  ? 7   SER H N   1 
ATOM   44   C CA  . SER A 1 7   ? 3.793   7.874   -31.015 1.00 69.73  ? 7   SER H CA  1 
ATOM   45   C C   . SER A 1 7   ? 3.416   8.030   -29.550 1.00 69.06  ? 7   SER H C   1 
ATOM   46   O O   . SER A 1 7   ? 2.879   9.059   -29.132 1.00 67.02  ? 7   SER H O   1 
ATOM   47   C CB  . SER A 1 7   ? 5.285   8.159   -31.223 1.00 66.10  ? 7   SER H CB  1 
ATOM   48   O OG  . SER A 1 7   ? 5.600   9.500   -30.891 1.00 68.71  ? 7   SER H OG  1 
ATOM   49   N N   . GLY A 1 8   ? 3.706   6.991   -28.771 1.00 70.28  ? 8   GLY H N   1 
ATOM   50   C CA  . GLY A 1 8   ? 3.374   6.978   -27.367 1.00 70.78  ? 8   GLY H CA  1 
ATOM   51   C C   . GLY A 1 8   ? 2.869   5.626   -26.908 1.00 66.65  ? 8   GLY H C   1 
ATOM   52   O O   . GLY A 1 8   ? 2.743   4.682   -27.695 1.00 64.59  ? 8   GLY H O   1 
ATOM   53   N N   . PRO A 1 9   ? 2.573   5.505   -25.615 1.00 67.94  ? 9   PRO H N   1 
ATOM   54   C CA  . PRO A 1 9   ? 2.127   4.213   -25.084 1.00 62.25  ? 9   PRO H CA  1 
ATOM   55   C C   . PRO A 1 9   ? 0.724   3.869   -25.558 1.00 60.18  ? 9   PRO H C   1 
ATOM   56   O O   . PRO A 1 9   ? -0.145  4.737   -25.674 1.00 59.08  ? 9   PRO H O   1 
ATOM   57   C CB  . PRO A 1 9   ? 2.169   4.424   -23.567 1.00 56.29  ? 9   PRO H CB  1 
ATOM   58   C CG  . PRO A 1 9   ? 1.934   5.890   -23.399 1.00 62.78  ? 9   PRO H CG  1 
ATOM   59   C CD  . PRO A 1 9   ? 2.607   6.551   -24.576 1.00 67.07  ? 9   PRO H CD  1 
ATOM   60   N N   . GLY A 1 10  ? 0.511   2.586   -25.833 1.00 56.13  ? 10  GLY H N   1 
ATOM   61   C CA  . GLY A 1 10  ? -0.794  2.087   -26.203 1.00 48.35  ? 10  GLY H CA  1 
ATOM   62   C C   . GLY A 1 10  ? -1.626  1.566   -25.057 1.00 53.82  ? 10  GLY H C   1 
ATOM   63   O O   . GLY A 1 10  ? -2.780  1.176   -25.262 1.00 54.15  ? 10  GLY H O   1 
ATOM   64   N N   . LEU A 1 11  ? -1.074  1.544   -23.845 1.00 50.62  ? 11  LEU H N   1 
ATOM   65   C CA  . LEU A 1 11  ? -1.786  1.065   -22.666 1.00 51.90  ? 11  LEU H CA  1 
ATOM   66   C C   . LEU A 1 11  ? -1.533  2.044   -21.532 1.00 52.99  ? 11  LEU H C   1 
ATOM   67   O O   . LEU A 1 11  ? -0.380  2.258   -21.144 1.00 53.54  ? 11  LEU H O   1 
ATOM   68   C CB  . LEU A 1 11  ? -1.326  -0.344  -22.279 1.00 46.51  ? 11  LEU H CB  1 
ATOM   69   C CG  . LEU A 1 11  ? -2.330  -1.309  -21.637 1.00 49.20  ? 11  LEU H CG  1 
ATOM   70   C CD1 . LEU A 1 11  ? -1.654  -2.638  -21.343 1.00 49.71  ? 11  LEU H CD1 1 
ATOM   71   C CD2 . LEU A 1 11  ? -2.954  -0.735  -20.372 1.00 51.48  ? 11  LEU H CD2 1 
ATOM   72   N N   . VAL A 1 12  ? -2.602  2.637   -21.003 1.00 51.99  ? 12  VAL H N   1 
ATOM   73   C CA  . VAL A 1 12  ? -2.522  3.539   -19.860 1.00 53.04  ? 12  VAL H CA  1 
ATOM   74   C C   . VAL A 1 12  ? -3.504  3.059   -18.800 1.00 50.70  ? 12  VAL H C   1 
ATOM   75   O O   . VAL A 1 12  ? -4.576  2.535   -19.121 1.00 50.51  ? 12  VAL H O   1 
ATOM   76   C CB  . VAL A 1 12  ? -2.795  5.011   -20.250 1.00 57.67  ? 12  VAL H CB  1 
ATOM   77   C CG1 . VAL A 1 12  ? -2.036  5.385   -21.518 1.00 58.92  ? 12  VAL H CG1 1 
ATOM   78   C CG2 . VAL A 1 12  ? -4.280  5.277   -20.412 1.00 56.76  ? 12  VAL H CG2 1 
ATOM   79   N N   . LYS A 1 13  ? -3.117  3.198   -17.538 1.00 58.72  ? 13  LYS H N   1 
ATOM   80   C CA  . LYS A 1 13  ? -3.983  2.792   -16.444 1.00 50.68  ? 13  LYS H CA  1 
ATOM   81   C C   . LYS A 1 13  ? -5.049  3.856   -16.193 1.00 50.32  ? 13  LYS H C   1 
ATOM   82   O O   . LYS A 1 13  ? -4.812  5.045   -16.421 1.00 51.50  ? 13  LYS H O   1 
ATOM   83   C CB  . LYS A 1 13  ? -3.169  2.587   -15.171 1.00 54.50  ? 13  LYS H CB  1 
ATOM   84   C CG  . LYS A 1 13  ? -1.963  1.665   -15.310 1.00 56.58  ? 13  LYS H CG  1 
ATOM   85   C CD  . LYS A 1 13  ? -2.239  0.286   -14.735 1.00 54.29  ? 13  LYS H CD  1 
ATOM   86   C CE  . LYS A 1 13  ? -1.310  -0.758  -15.332 1.00 60.22  ? 13  LYS H CE  1 
ATOM   87   N NZ  . LYS A 1 13  ? -1.598  -2.124  -14.812 1.00 60.12  ? 13  LYS H NZ  1 
ATOM   88   N N   . PRO A 1 14  ? -6.234  3.453   -15.736 1.00 51.35  ? 14  PRO H N   1 
ATOM   89   C CA  . PRO A 1 14  ? -7.276  4.441   -15.433 1.00 51.18  ? 14  PRO H CA  1 
ATOM   90   C C   . PRO A 1 14  ? -6.814  5.424   -14.366 1.00 51.76  ? 14  PRO H C   1 
ATOM   91   O O   . PRO A 1 14  ? -6.050  5.081   -13.460 1.00 53.40  ? 14  PRO H O   1 
ATOM   92   C CB  . PRO A 1 14  ? -8.446  3.583   -14.940 1.00 47.88  ? 14  PRO H CB  1 
ATOM   93   C CG  . PRO A 1 14  ? -8.212  2.243   -15.564 1.00 44.74  ? 14  PRO H CG  1 
ATOM   94   C CD  . PRO A 1 14  ? -6.723  2.071   -15.594 1.00 52.02  ? 14  PRO H CD  1 
ATOM   95   N N   . SER A 1 15  ? -7.279  6.667   -14.501 1.00 57.14  ? 15  SER H N   1 
ATOM   96   C CA  . SER A 1 15  ? -6.965  7.812   -13.648 1.00 61.10  ? 15  SER H CA  1 
ATOM   97   C C   . SER A 1 15  ? -5.538  8.320   -13.831 1.00 59.00  ? 15  SER H C   1 
ATOM   98   O O   . SER A 1 15  ? -5.177  9.331   -13.217 1.00 67.52  ? 15  SER H O   1 
ATOM   99   C CB  . SER A 1 15  ? -7.205  7.524   -12.158 1.00 54.87  ? 15  SER H CB  1 
ATOM   100  O OG  . SER A 1 15  ? -6.210  6.659   -11.637 1.00 49.15  ? 15  SER H OG  1 
ATOM   101  N N   . GLN A 1 16  ? -4.715  7.661   -14.643 1.00 64.41  ? 16  GLN H N   1 
ATOM   102  C CA  . GLN A 1 16  ? -3.366  8.130   -14.933 1.00 58.42  ? 16  GLN H CA  1 
ATOM   103  C C   . GLN A 1 16  ? -3.404  9.081   -16.132 1.00 64.33  ? 16  GLN H C   1 
ATOM   104  O O   . GLN A 1 16  ? -4.469  9.577   -16.513 1.00 63.28  ? 16  GLN H O   1 
ATOM   105  C CB  . GLN A 1 16  ? -2.426  6.940   -15.156 1.00 56.59  ? 16  GLN H CB  1 
ATOM   106  C CG  . GLN A 1 16  ? -2.174  6.092   -13.921 1.00 59.10  ? 16  GLN H CG  1 
ATOM   107  C CD  . GLN A 1 16  ? -1.081  5.066   -14.147 1.00 65.72  ? 16  GLN H CD  1 
ATOM   108  O OE1 . GLN A 1 16  ? -0.540  4.954   -15.247 1.00 68.25  ? 16  GLN H OE1 1 
ATOM   109  N NE2 . GLN A 1 16  ? -0.751  4.311   -13.106 1.00 72.25  ? 16  GLN H NE2 1 
ATOM   110  N N   . SER A 1 17  ? -2.248  9.349   -16.735 1.00 70.95  ? 17  SER H N   1 
ATOM   111  C CA  . SER A 1 17  ? -2.119  10.337  -17.796 1.00 69.84  ? 17  SER H CA  1 
ATOM   112  C C   . SER A 1 17  ? -1.799  9.666   -19.124 1.00 64.61  ? 17  SER H C   1 
ATOM   113  O O   . SER A 1 17  ? -0.959  8.763   -19.190 1.00 62.51  ? 17  SER H O   1 
ATOM   114  C CB  . SER A 1 17  ? -1.021  11.349  -17.462 1.00 72.93  ? 17  SER H CB  1 
ATOM   115  O OG  . SER A 1 17  ? 0.254   10.727  -17.468 1.00 77.56  ? 17  SER H OG  1 
ATOM   116  N N   . LEU A 1 18  ? -2.476  10.110  -20.179 1.00 67.72  ? 18  LEU H N   1 
ATOM   117  C CA  . LEU A 1 18  ? -2.207  9.659   -21.539 1.00 65.27  ? 18  LEU H CA  1 
ATOM   118  C C   . LEU A 1 18  ? -1.447  10.756  -22.277 1.00 65.59  ? 18  LEU H C   1 
ATOM   119  O O   . LEU A 1 18  ? -1.959  11.869  -22.443 1.00 60.74  ? 18  LEU H O   1 
ATOM   120  C CB  . LEU A 1 18  ? -3.499  9.311   -22.277 1.00 59.42  ? 18  LEU H CB  1 
ATOM   121  C CG  . LEU A 1 18  ? -3.385  9.207   -23.798 1.00 66.15  ? 18  LEU H CG  1 
ATOM   122  C CD1 . LEU A 1 18  ? -2.473  8.054   -24.198 1.00 61.53  ? 18  LEU H CD1 1 
ATOM   123  C CD2 . LEU A 1 18  ? -4.759  9.056   -24.435 1.00 61.31  ? 18  LEU H CD2 1 
ATOM   124  N N   . SER A 1 19  ? -0.232  10.442  -22.714 1.00 68.45  ? 19  SER H N   1 
ATOM   125  C CA  . SER A 1 19  ? 0.623   11.384  -23.424 1.00 73.52  ? 19  SER H CA  1 
ATOM   126  C C   . SER A 1 19  ? 0.951   10.830  -24.803 1.00 66.81  ? 19  SER H C   1 
ATOM   127  O O   . SER A 1 19  ? 1.440   9.702   -24.922 1.00 65.84  ? 19  SER H O   1 
ATOM   128  C CB  . SER A 1 19  ? 1.910   11.663  -22.642 1.00 69.28  ? 19  SER H CB  1 
ATOM   129  O OG  . SER A 1 19  ? 1.754   12.791  -21.798 1.00 74.83  ? 19  SER H OG  1 
ATOM   130  N N   . LEU A 1 20  ? 0.681   11.620  -25.840 1.00 69.51  ? 20  LEU H N   1 
ATOM   131  C CA  . LEU A 1 20  ? 0.971   11.228  -27.211 1.00 71.43  ? 20  LEU H CA  1 
ATOM   132  C C   . LEU A 1 20  ? 1.718   12.350  -27.913 1.00 75.96  ? 20  LEU H C   1 
ATOM   133  O O   . LEU A 1 20  ? 1.410   13.530  -27.719 1.00 73.58  ? 20  LEU H O   1 
ATOM   134  C CB  . LEU A 1 20  ? -0.310  10.889  -27.984 1.00 67.04  ? 20  LEU H CB  1 
ATOM   135  C CG  . LEU A 1 20  ? -1.034  9.609   -27.564 1.00 66.42  ? 20  LEU H CG  1 
ATOM   136  C CD1 . LEU A 1 20  ? -2.296  9.417   -28.385 1.00 65.39  ? 20  LEU H CD1 1 
ATOM   137  C CD2 . LEU A 1 20  ? -0.113  8.405   -27.696 1.00 63.66  ? 20  LEU H CD2 1 
ATOM   138  N N   . THR A 1 21  ? 2.697   11.974  -28.730 1.00 79.69  ? 21  THR H N   1 
ATOM   139  C CA  . THR A 1 21  ? 3.502   12.916  -29.492 1.00 80.25  ? 21  THR H CA  1 
ATOM   140  C C   . THR A 1 21  ? 3.244   12.719  -30.979 1.00 78.62  ? 21  THR H C   1 
ATOM   141  O O   . THR A 1 21  ? 3.159   11.584  -31.458 1.00 74.53  ? 21  THR H O   1 
ATOM   142  C CB  . THR A 1 21  ? 4.994   12.739  -29.193 1.00 81.19  ? 21  THR H CB  1 
ATOM   143  O OG1 . THR A 1 21  ? 5.481   11.570  -29.861 1.00 78.90  ? 21  THR H OG1 1 
ATOM   144  C CG2 . THR A 1 21  ? 5.221   12.585  -27.696 1.00 74.37  ? 21  THR H CG2 1 
ATOM   145  N N   . CYS A 1 22  ? 3.124   13.827  -31.704 1.00 84.19  ? 22  CYS H N   1 
ATOM   146  C CA  . CYS A 1 22  ? 2.939   13.816  -33.150 1.00 84.29  ? 22  CYS H CA  1 
ATOM   147  C C   . CYS A 1 22  ? 4.114   14.522  -33.809 1.00 83.95  ? 22  CYS H C   1 
ATOM   148  O O   . CYS A 1 22  ? 4.353   15.706  -33.552 1.00 85.00  ? 22  CYS H O   1 
ATOM   149  C CB  . CYS A 1 22  ? 1.625   14.491  -33.544 1.00 78.63  ? 22  CYS H CB  1 
ATOM   150  S SG  . CYS A 1 22  ? 1.265   14.467  -35.320 1.00 82.41  ? 22  CYS H SG  1 
ATOM   151  N N   . SER A 1 23  ? 4.837   13.798  -34.657 1.00 80.63  ? 23  SER H N   1 
ATOM   152  C CA  . SER A 1 23  ? 5.948   14.365  -35.407 1.00 81.85  ? 23  SER H CA  1 
ATOM   153  C C   . SER A 1 23  ? 5.451   14.834  -36.767 1.00 83.65  ? 23  SER H C   1 
ATOM   154  O O   . SER A 1 23  ? 4.855   14.056  -37.520 1.00 82.11  ? 23  SER H O   1 
ATOM   155  C CB  . SER A 1 23  ? 7.069   13.339  -35.574 1.00 78.15  ? 23  SER H CB  1 
ATOM   156  O OG  . SER A 1 23  ? 7.439   12.780  -34.325 1.00 80.43  ? 23  SER H OG  1 
ATOM   157  N N   . VAL A 1 24  ? 5.695   16.103  -37.076 1.00 82.59  ? 24  VAL H N   1 
ATOM   158  C CA  . VAL A 1 24  ? 5.215   16.694  -38.318 1.00 82.98  ? 24  VAL H CA  1 
ATOM   159  C C   . VAL A 1 24  ? 6.370   16.892  -39.292 1.00 86.03  ? 24  VAL H C   1 
ATOM   160  O O   . VAL A 1 24  ? 6.999   17.950  -39.318 1.00 86.67  ? 24  VAL H O   1 
ATOM   161  C CB  . VAL A 1 24  ? 4.495   18.027  -38.053 1.00 79.87  ? 24  VAL H CB  1 
ATOM   162  C CG1 . VAL A 1 24  ? 3.728   18.472  -39.288 1.00 80.52  ? 24  VAL H CG1 1 
ATOM   163  C CG2 . VAL A 1 24  ? 3.568   17.904  -36.854 1.00 82.16  ? 24  VAL H CG2 1 
ATOM   164  N N   . GLY A 1 26  ? 7.613   18.406  -42.739 1.00 86.71  ? 26  GLY H N   1 
ATOM   165  C CA  . GLY A 1 26  ? 7.255   18.784  -44.093 1.00 88.64  ? 26  GLY H CA  1 
ATOM   166  C C   . GLY A 1 26  ? 6.531   20.114  -44.182 1.00 88.99  ? 26  GLY H C   1 
ATOM   167  O O   . GLY A 1 26  ? 6.255   20.602  -45.279 1.00 85.69  ? 26  GLY H O   1 
ATOM   168  N N   . TYR A 1 27  ? 6.227   20.704  -43.027 1.00 91.01  ? 27  TYR H N   1 
ATOM   169  C CA  . TYR A 1 27  ? 5.509   21.971  -42.973 1.00 92.22  ? 27  TYR H CA  1 
ATOM   170  C C   . TYR A 1 27  ? 5.595   22.530  -41.559 1.00 93.79  ? 27  TYR H C   1 
ATOM   171  O O   . TYR A 1 27  ? 5.619   21.778  -40.581 1.00 92.71  ? 27  TYR H O   1 
ATOM   172  C CB  . TYR A 1 27  ? 4.048   21.804  -43.413 1.00 92.22  ? 27  TYR H CB  1 
ATOM   173  C CG  . TYR A 1 27  ? 3.270   23.098  -43.468 1.00 92.40  ? 27  TYR H CG  1 
ATOM   174  C CD1 . TYR A 1 27  ? 3.470   24.008  -44.498 1.00 89.12  ? 27  TYR H CD1 1 
ATOM   175  C CD2 . TYR A 1 27  ? 2.307   23.391  -42.514 1.00 93.07  ? 27  TYR H CD2 1 
ATOM   176  C CE1 . TYR A 1 27  ? 2.757   25.190  -44.556 1.00 88.71  ? 27  TYR H CE1 1 
ATOM   177  C CE2 . TYR A 1 27  ? 1.587   24.569  -42.565 1.00 93.26  ? 27  TYR H CE2 1 
ATOM   178  C CZ  . TYR A 1 27  ? 1.814   25.464  -43.587 1.00 93.69  ? 27  TYR H CZ  1 
ATOM   179  O OH  . TYR A 1 27  ? 1.097   26.636  -43.640 1.00 92.54  ? 27  TYR H OH  1 
ATOM   180  N N   . SER A 1 28  ? 5.645   23.858  -41.468 1.00 92.99  ? 28  SER H N   1 
ATOM   181  C CA  . SER A 1 28  ? 5.805   24.569  -40.208 1.00 96.90  ? 28  SER H CA  1 
ATOM   182  C C   . SER A 1 28  ? 4.470   24.722  -39.479 1.00 97.71  ? 28  SER H C   1 
ATOM   183  O O   . SER A 1 28  ? 3.394   24.683  -40.078 1.00 99.67  ? 28  SER H O   1 
ATOM   184  C CB  . SER A 1 28  ? 6.428   25.947  -40.446 1.00 97.20  ? 28  SER H CB  1 
ATOM   185  O OG  . SER A 1 28  ? 6.373   26.737  -39.272 1.00 94.00  ? 28  SER H OG  1 
ATOM   186  N N   . ILE A 1 29  ? 4.557   24.911  -38.157 1.00 97.21  ? 29  ILE H N   1 
ATOM   187  C CA  . ILE A 1 29  ? 3.368   25.017  -37.316 1.00 97.03  ? 29  ILE H CA  1 
ATOM   188  C C   . ILE A 1 29  ? 2.871   26.447  -37.145 1.00 96.90  ? 29  ILE H C   1 
ATOM   189  O O   . ILE A 1 29  ? 1.821   26.652  -36.520 1.00 93.31  ? 29  ILE H O   1 
ATOM   190  C CB  . ILE A 1 29  ? 3.617   24.413  -35.916 1.00 98.43  ? 29  ILE H CB  1 
ATOM   191  C CG1 . ILE A 1 29  ? 5.005   23.773  -35.831 1.00 99.42  ? 29  ILE H CG1 1 
ATOM   192  C CG2 . ILE A 1 29  ? 2.531   23.407  -35.567 1.00 96.76  ? 29  ILE H CG2 1 
ATOM   193  C CD1 . ILE A 1 29  ? 6.104   24.723  -35.380 1.00 101.28 ? 29  ILE H CD1 1 
ATOM   194  N N   . THR A 1 30  ? 3.579   27.441  -37.674 1.00 100.64 ? 30  THR H N   1 
ATOM   195  C CA  . THR A 1 30  ? 3.097   28.818  -37.599 1.00 100.56 ? 30  THR H CA  1 
ATOM   196  C C   . THR A 1 30  ? 2.460   29.269  -38.910 1.00 100.11 ? 30  THR H C   1 
ATOM   197  O O   . THR A 1 30  ? 2.617   28.620  -39.944 1.00 97.72  ? 30  THR H O   1 
ATOM   198  C CB  . THR A 1 30  ? 4.228   29.799  -37.229 1.00 100.46 ? 30  THR H CB  1 
ATOM   199  O OG1 . THR A 1 30  ? 5.235   29.778  -38.247 1.00 106.87 ? 30  THR H OG1 1 
ATOM   200  C CG2 . THR A 1 30  ? 4.850   29.417  -35.893 1.00 98.96  ? 30  THR H CG2 1 
ATOM   201  N N   . TYR A 1 34  ? -4.752  25.351  -38.125 1.00 84.82  ? 34  TYR H N   1 
ATOM   202  C CA  . TYR A 1 34  ? -4.812  24.698  -36.823 1.00 87.84  ? 34  TYR H CA  1 
ATOM   203  C C   . TYR A 1 34  ? -4.340  23.249  -36.921 1.00 86.20  ? 34  TYR H C   1 
ATOM   204  O O   . TYR A 1 34  ? -4.581  22.576  -37.923 1.00 85.15  ? 34  TYR H O   1 
ATOM   205  C CB  . TYR A 1 34  ? -6.235  24.749  -36.261 1.00 88.47  ? 34  TYR H CB  1 
ATOM   206  C CG  . TYR A 1 34  ? -6.602  26.060  -35.598 1.00 89.36  ? 34  TYR H CG  1 
ATOM   207  C CD1 . TYR A 1 34  ? -6.026  26.439  -34.393 1.00 90.94  ? 34  TYR H CD1 1 
ATOM   208  C CD2 . TYR A 1 34  ? -7.535  26.913  -36.175 1.00 91.39  ? 34  TYR H CD2 1 
ATOM   209  C CE1 . TYR A 1 34  ? -6.364  27.636  -33.785 1.00 93.40  ? 34  TYR H CE1 1 
ATOM   210  C CE2 . TYR A 1 34  ? -7.879  28.110  -35.574 1.00 99.78  ? 34  TYR H CE2 1 
ATOM   211  C CZ  . TYR A 1 34  ? -7.291  28.466  -34.380 1.00 100.20 ? 34  TYR H CZ  1 
ATOM   212  O OH  . TYR A 1 34  ? -7.630  29.657  -33.778 1.00 104.15 ? 34  TYR H OH  1 
ATOM   213  N N   . TRP A 1 35  ? -3.667  22.776  -35.875 1.00 84.19  ? 35  TRP H N   1 
ATOM   214  C CA  . TRP A 1 35  ? -3.195  21.398  -35.787 1.00 88.04  ? 35  TRP H CA  1 
ATOM   215  C C   . TRP A 1 35  ? -3.990  20.672  -34.713 1.00 84.62  ? 35  TRP H C   1 
ATOM   216  O O   . TRP A 1 35  ? -3.902  21.015  -33.529 1.00 88.28  ? 35  TRP H O   1 
ATOM   217  C CB  . TRP A 1 35  ? -1.692  21.335  -35.506 1.00 88.43  ? 35  TRP H CB  1 
ATOM   218  C CG  . TRP A 1 35  ? -0.829  21.648  -36.703 1.00 91.69  ? 35  TRP H CG  1 
ATOM   219  C CD1 . TRP A 1 35  ? -0.014  20.771  -37.358 1.00 90.13  ? 35  TRP H CD1 1 
ATOM   220  C CD2 . TRP A 1 35  ? -0.713  22.898  -37.402 1.00 93.94  ? 35  TRP H CD2 1 
ATOM   221  N NE1 . TRP A 1 35  ? 0.611   21.395  -38.408 1.00 93.86  ? 35  TRP H NE1 1 
ATOM   222  C CE2 . TRP A 1 35  ? 0.199   22.700  -38.458 1.00 91.33  ? 35  TRP H CE2 1 
ATOM   223  C CE3 . TRP A 1 35  ? -1.281  24.165  -37.232 1.00 89.75  ? 35  TRP H CE3 1 
ATOM   224  C CZ2 . TRP A 1 35  ? 0.550   23.717  -39.342 1.00 94.13  ? 35  TRP H CZ2 1 
ATOM   225  C CZ3 . TRP A 1 35  ? -0.932  25.172  -38.114 1.00 92.81  ? 35  TRP H CZ3 1 
ATOM   226  C CH2 . TRP A 1 35  ? -0.024  24.943  -39.153 1.00 95.03  ? 35  TRP H CH2 1 
ATOM   227  N N   . ASN A 1 36  A -4.757  19.669  -35.133 1.00 83.11  ? 35  ASN H N   1 
ATOM   228  C CA  . ASN A 1 36  A -5.822  19.083  -34.339 1.00 80.96  ? 35  ASN H CA  1 
ATOM   229  C C   . ASN A 1 36  A -5.454  17.683  -33.863 1.00 74.65  ? 35  ASN H C   1 
ATOM   230  O O   . ASN A 1 36  A -4.701  16.954  -34.520 1.00 69.72  ? 35  ASN H O   1 
ATOM   231  C CB  . ASN A 1 36  A -7.121  18.997  -35.150 1.00 81.81  ? 35  ASN H CB  1 
ATOM   232  C CG  . ASN A 1 36  A -7.485  20.307  -35.819 1.00 83.08  ? 35  ASN H CG  1 
ATOM   233  O OD1 . ASN A 1 36  A -6.896  21.347  -35.537 1.00 86.06  ? 35  ASN H OD1 1 
ATOM   234  N ND2 . ASN A 1 36  A -8.463  20.259  -36.717 1.00 77.79  ? 35  ASN H ND2 1 
ATOM   235  N N   . TRP A 1 37  ? -6.018  17.319  -32.714 1.00 72.72  ? 36  TRP H N   1 
ATOM   236  C CA  . TRP A 1 37  ? -6.088  15.939  -32.246 1.00 68.98  ? 36  TRP H CA  1 
ATOM   237  C C   . TRP A 1 37  ? -7.533  15.476  -32.354 1.00 66.25  ? 36  TRP H C   1 
ATOM   238  O O   . TRP A 1 37  ? -8.435  16.121  -31.810 1.00 65.96  ? 36  TRP H O   1 
ATOM   239  C CB  . TRP A 1 37  ? -5.591  15.804  -30.807 1.00 64.41  ? 36  TRP H CB  1 
ATOM   240  C CG  . TRP A 1 37  ? -4.103  15.832  -30.655 1.00 65.52  ? 36  TRP H CG  1 
ATOM   241  C CD1 . TRP A 1 37  ? -3.340  16.880  -30.231 1.00 67.21  ? 36  TRP H CD1 1 
ATOM   242  C CD2 . TRP A 1 37  ? -3.198  14.749  -30.897 1.00 65.62  ? 36  TRP H CD2 1 
ATOM   243  N NE1 . TRP A 1 37  ? -2.014  16.521  -30.208 1.00 68.93  ? 36  TRP H NE1 1 
ATOM   244  C CE2 . TRP A 1 37  ? -1.900  15.217  -30.613 1.00 68.77  ? 36  TRP H CE2 1 
ATOM   245  C CE3 . TRP A 1 37  ? -3.358  13.430  -31.334 1.00 66.17  ? 36  TRP H CE3 1 
ATOM   246  C CZ2 . TRP A 1 37  ? -0.769  14.414  -30.750 1.00 72.38  ? 36  TRP H CZ2 1 
ATOM   247  C CZ3 . TRP A 1 37  ? -2.234  12.634  -31.470 1.00 63.47  ? 36  TRP H CZ3 1 
ATOM   248  C CH2 . TRP A 1 37  ? -0.957  13.129  -31.179 1.00 68.25  ? 36  TRP H CH2 1 
ATOM   249  N N   . ILE A 1 38  ? -7.752  14.365  -33.055 1.00 61.88  ? 37  ILE H N   1 
ATOM   250  C CA  . ILE A 1 38  ? -9.087  13.827  -33.289 1.00 61.36  ? 37  ILE H CA  1 
ATOM   251  C C   . ILE A 1 38  ? -9.061  12.344  -32.952 1.00 58.10  ? 37  ILE H C   1 
ATOM   252  O O   . ILE A 1 38  ? -8.174  11.618  -33.411 1.00 57.66  ? 37  ILE H O   1 
ATOM   253  C CB  . ILE A 1 38  ? -9.530  14.040  -34.751 1.00 65.74  ? 37  ILE H CB  1 
ATOM   254  C CG1 . ILE A 1 38  ? -9.173  15.450  -35.226 1.00 65.44  ? 37  ILE H CG1 1 
ATOM   255  C CG2 . ILE A 1 38  ? -11.023 13.795  -34.898 1.00 60.53  ? 37  ILE H CG2 1 
ATOM   256  C CD1 . ILE A 1 38  ? -9.183  15.618  -36.729 1.00 63.66  ? 37  ILE H CD1 1 
ATOM   257  N N   . ARG A 1 39  ? -10.033 11.882  -32.174 1.00 60.12  ? 38  ARG H N   1 
ATOM   258  C CA  . ARG A 1 39  ? -10.055 10.482  -31.779 1.00 58.62  ? 38  ARG H CA  1 
ATOM   259  C C   . ARG A 1 39  ? -11.319 9.807   -32.291 1.00 55.03  ? 38  ARG H C   1 
ATOM   260  O O   . ARG A 1 39  ? -12.343 10.453  -32.528 1.00 56.76  ? 38  ARG H O   1 
ATOM   261  C CB  . ARG A 1 39  ? -9.960  10.303  -30.257 1.00 60.59  ? 38  ARG H CB  1 
ATOM   262  C CG  . ARG A 1 39  ? -11.139 10.837  -29.463 1.00 59.83  ? 38  ARG H CG  1 
ATOM   263  C CD  . ARG A 1 39  ? -10.951 10.529  -27.984 1.00 60.36  ? 38  ARG H CD  1 
ATOM   264  N NE  . ARG A 1 39  ? -12.002 11.100  -27.153 1.00 63.85  ? 38  ARG H NE  1 
ATOM   265  C CZ  . ARG A 1 39  ? -12.034 11.019  -25.830 1.00 62.76  ? 38  ARG H CZ  1 
ATOM   266  N NH1 . ARG A 1 39  ? -11.079 10.403  -25.152 1.00 51.64  ? 38  ARG H NH1 1 
ATOM   267  N NH2 . ARG A 1 39  ? -13.049 11.569  -25.170 1.00 66.52  ? 38  ARG H NH2 1 
ATOM   268  N N   . GLN A 1 40  ? -11.222 8.493   -32.462 1.00 59.66  ? 39  GLN H N   1 
ATOM   269  C CA  . GLN A 1 40  ? -12.320 7.664   -32.940 1.00 59.14  ? 39  GLN H CA  1 
ATOM   270  C C   . GLN A 1 40  ? -12.504 6.513   -31.964 1.00 55.42  ? 39  GLN H C   1 
ATOM   271  O O   . GLN A 1 40  ? -11.555 5.771   -31.688 1.00 55.51  ? 39  GLN H O   1 
ATOM   272  C CB  . GLN A 1 40  ? -12.056 7.147   -34.357 1.00 56.04  ? 39  GLN H CB  1 
ATOM   273  C CG  . GLN A 1 40  ? -13.262 6.482   -35.002 1.00 56.53  ? 39  GLN H CG  1 
ATOM   274  C CD  . GLN A 1 40  ? -13.047 6.183   -36.473 1.00 51.65  ? 39  GLN H CD  1 
ATOM   275  O OE1 . GLN A 1 40  ? -11.933 5.884   -36.902 1.00 56.72  ? 39  GLN H OE1 1 
ATOM   276  N NE2 . GLN A 1 40  ? -14.117 6.265   -37.256 1.00 50.71  ? 39  GLN H NE2 1 
ATOM   277  N N   . PHE A 1 41  ? -13.711 6.382   -31.432 1.00 52.42  ? 40  PHE H N   1 
ATOM   278  C CA  . PHE A 1 41  ? -14.016 5.376   -30.430 1.00 55.27  ? 40  PHE H CA  1 
ATOM   279  C C   . PHE A 1 41  ? -14.191 4.019   -31.103 1.00 55.55  ? 40  PHE H C   1 
ATOM   280  O O   . PHE A 1 41  ? -14.284 3.930   -32.329 1.00 52.97  ? 40  PHE H O   1 
ATOM   281  C CB  . PHE A 1 41  ? -15.261 5.799   -29.653 1.00 58.10  ? 40  PHE H CB  1 
ATOM   282  C CG  . PHE A 1 41  ? -15.115 7.125   -28.955 1.00 58.48  ? 40  PHE H CG  1 
ATOM   283  C CD1 . PHE A 1 41  ? -14.418 7.221   -27.761 1.00 59.03  ? 40  PHE H CD1 1 
ATOM   284  C CD2 . PHE A 1 41  ? -15.669 8.274   -29.495 1.00 60.93  ? 40  PHE H CD2 1 
ATOM   285  C CE1 . PHE A 1 41  ? -14.278 8.438   -27.118 1.00 62.48  ? 40  PHE H CE1 1 
ATOM   286  C CE2 . PHE A 1 41  ? -15.533 9.494   -28.857 1.00 62.97  ? 40  PHE H CE2 1 
ATOM   287  C CZ  . PHE A 1 41  ? -14.837 9.575   -27.667 1.00 62.86  ? 40  PHE H CZ  1 
ATOM   288  N N   . PRO A 1 42  ? -14.217 2.931   -30.323 1.00 51.35  ? 41  PRO H N   1 
ATOM   289  C CA  . PRO A 1 42  ? -14.567 1.620   -30.902 1.00 46.90  ? 41  PRO H CA  1 
ATOM   290  C C   . PRO A 1 42  ? -15.844 1.623   -31.726 1.00 54.95  ? 41  PRO H C   1 
ATOM   291  O O   . PRO A 1 42  ? -15.978 0.807   -32.647 1.00 58.65  ? 41  PRO H O   1 
ATOM   292  C CB  . PRO A 1 42  ? -14.691 0.721   -29.665 1.00 49.60  ? 41  PRO H CB  1 
ATOM   293  C CG  . PRO A 1 42  ? -13.749 1.328   -28.685 1.00 47.75  ? 41  PRO H CG  1 
ATOM   294  C CD  . PRO A 1 42  ? -13.808 2.815   -28.911 1.00 51.82  ? 41  PRO H CD  1 
ATOM   295  N N   . GLY A 1 43  ? -16.787 2.510   -31.427 1.00 54.58  ? 42  GLY H N   1 
ATOM   296  C CA  . GLY A 1 43  ? -18.038 2.584   -32.148 1.00 49.56  ? 42  GLY H CA  1 
ATOM   297  C C   . GLY A 1 43  ? -17.962 3.368   -33.437 1.00 57.02  ? 42  GLY H C   1 
ATOM   298  O O   . GLY A 1 43  ? -18.990 3.584   -34.086 1.00 55.44  ? 42  GLY H O   1 
ATOM   299  N N   . ASN A 1 44  ? -16.758 3.821   -33.800 1.00 58.88  ? 43  ASN H N   1 
ATOM   300  C CA  . ASN A 1 44  ? -16.448 4.515   -35.049 1.00 55.37  ? 43  ASN H CA  1 
ATOM   301  C C   . ASN A 1 44  ? -16.957 5.950   -35.057 1.00 56.68  ? 43  ASN H C   1 
ATOM   302  O O   . ASN A 1 44  ? -17.122 6.546   -36.126 1.00 59.58  ? 43  ASN H O   1 
ATOM   303  C CB  . ASN A 1 44  ? -16.971 3.760   -36.279 1.00 54.37  ? 43  ASN H CB  1 
ATOM   304  C CG  . ASN A 1 44  ? -16.287 2.422   -36.475 1.00 57.19  ? 43  ASN H CG  1 
ATOM   305  O OD1 . ASN A 1 44  ? -15.073 2.303   -36.303 1.00 60.42  ? 43  ASN H OD1 1 
ATOM   306  N ND2 . ASN A 1 44  ? -17.061 1.408   -36.842 1.00 58.36  ? 43  ASN H ND2 1 
ATOM   307  N N   . LYS A 1 45  ? -17.213 6.516   -33.880 1.00 56.98  ? 44  LYS H N   1 
ATOM   308  C CA  . LYS A 1 45  ? -17.593 7.915   -33.759 1.00 61.12  ? 44  LYS H CA  1 
ATOM   309  C C   . LYS A 1 45  ? -16.341 8.778   -33.695 1.00 59.82  ? 44  LYS H C   1 
ATOM   310  O O   . LYS A 1 45  ? -15.448 8.527   -32.880 1.00 60.01  ? 44  LYS H O   1 
ATOM   311  C CB  . LYS A 1 45  ? -18.453 8.138   -32.515 1.00 61.93  ? 44  LYS H CB  1 
ATOM   312  C CG  . LYS A 1 45  ? -18.860 9.590   -32.299 1.00 63.38  ? 44  LYS H CG  1 
ATOM   313  C CD  . LYS A 1 45  ? -19.873 9.724   -31.173 1.00 60.25  ? 44  LYS H CD  1 
ATOM   314  C CE  . LYS A 1 45  ? -21.287 9.874   -31.714 1.00 63.43  ? 44  LYS H CE  1 
ATOM   315  N NZ  . LYS A 1 45  ? -21.652 8.785   -32.661 1.00 56.92  ? 44  LYS H NZ  1 
ATOM   316  N N   . LEU A 1 46  ? -16.281 9.793   -34.550 1.00 59.20  ? 45  LEU H N   1 
ATOM   317  C CA  . LEU A 1 46  ? -15.155 10.714  -34.575 1.00 62.12  ? 45  LEU H CA  1 
ATOM   318  C C   . LEU A 1 46  ? -15.455 11.911  -33.685 1.00 61.15  ? 45  LEU H C   1 
ATOM   319  O O   . LEU A 1 46  ? -16.590 12.394  -33.637 1.00 65.68  ? 45  LEU H O   1 
ATOM   320  C CB  . LEU A 1 46  ? -14.869 11.181  -36.004 1.00 56.79  ? 45  LEU H CB  1 
ATOM   321  C CG  . LEU A 1 46  ? -14.245 10.160  -36.958 1.00 54.85  ? 45  LEU H CG  1 
ATOM   322  C CD1 . LEU A 1 46  ? -14.423 10.602  -38.403 1.00 55.13  ? 45  LEU H CD1 1 
ATOM   323  C CD2 . LEU A 1 46  ? -12.774 9.948   -36.638 1.00 52.69  ? 45  LEU H CD2 1 
ATOM   324  N N   . GLU A 1 47  ? -14.434 12.388  -32.976 1.00 57.97  ? 46  GLU H N   1 
ATOM   325  C CA  . GLU A 1 47  ? -14.600 13.518  -32.069 1.00 64.41  ? 46  GLU H CA  1 
ATOM   326  C C   . GLU A 1 47  ? -13.346 14.375  -32.103 1.00 67.22  ? 46  GLU H C   1 
ATOM   327  O O   . GLU A 1 47  ? -12.250 13.893  -31.799 1.00 64.41  ? 46  GLU H O   1 
ATOM   328  C CB  . GLU A 1 47  ? -14.894 13.047  -30.640 1.00 65.15  ? 46  GLU H CB  1 
ATOM   329  C CG  . GLU A 1 47  ? -14.493 14.044  -29.559 1.00 66.00  ? 46  GLU H CG  1 
ATOM   330  C CD  . GLU A 1 47  ? -15.129 13.735  -28.219 1.00 74.31  ? 46  GLU H CD  1 
ATOM   331  O OE1 . GLU A 1 47  ? -16.313 13.338  -28.202 1.00 69.27  ? 46  GLU H OE1 1 
ATOM   332  O OE2 . GLU A 1 47  ? -14.450 13.893  -27.184 1.00 66.88  ? 46  GLU H OE2 1 
ATOM   333  N N   . TRP A 1 48  ? -13.508 15.640  -32.481 1.00 71.33  ? 47  TRP H N   1 
ATOM   334  C CA  . TRP A 1 48  ? -12.417 16.603  -32.412 1.00 71.95  ? 47  TRP H CA  1 
ATOM   335  C C   . TRP A 1 48  ? -12.191 17.016  -30.963 1.00 72.01  ? 47  TRP H C   1 
ATOM   336  O O   . TRP A 1 48  ? -13.110 17.508  -30.301 1.00 71.87  ? 47  TRP H O   1 
ATOM   337  C CB  . TRP A 1 48  ? -12.731 17.824  -33.271 1.00 72.04  ? 47  TRP H CB  1 
ATOM   338  C CG  . TRP A 1 48  ? -11.766 18.944  -33.059 1.00 76.74  ? 47  TRP H CG  1 
ATOM   339  C CD1 . TRP A 1 48  ? -10.461 18.989  -33.449 1.00 77.88  ? 47  TRP H CD1 1 
ATOM   340  C CD2 . TRP A 1 48  ? -12.025 20.177  -32.378 1.00 79.30  ? 47  TRP H CD2 1 
ATOM   341  N NE1 . TRP A 1 48  ? -9.893  20.180  -33.065 1.00 77.41  ? 47  TRP H NE1 1 
ATOM   342  C CE2 . TRP A 1 48  ? -10.833 20.927  -32.404 1.00 79.32  ? 47  TRP H CE2 1 
ATOM   343  C CE3 . TRP A 1 48  ? -13.151 20.722  -31.753 1.00 81.39  ? 47  TRP H CE3 1 
ATOM   344  C CZ2 . TRP A 1 48  ? -10.735 22.192  -31.830 1.00 81.53  ? 47  TRP H CZ2 1 
ATOM   345  C CZ3 . TRP A 1 48  ? -13.052 21.978  -31.185 1.00 83.85  ? 47  TRP H CZ3 1 
ATOM   346  C CH2 . TRP A 1 48  ? -11.853 22.699  -31.227 1.00 81.48  ? 47  TRP H CH2 1 
ATOM   347  N N   . MET A 1 49  ? -10.972 16.814  -30.466 1.00 68.48  ? 48  MET H N   1 
ATOM   348  C CA  . MET A 1 49  ? -10.663 17.150  -29.081 1.00 69.23  ? 48  MET H CA  1 
ATOM   349  C C   . MET A 1 49  ? -10.108 18.566  -28.936 1.00 79.01  ? 48  MET H C   1 
ATOM   350  O O   . MET A 1 49  ? -10.577 19.331  -28.088 1.00 79.26  ? 48  MET H O   1 
ATOM   351  C CB  . MET A 1 49  ? -9.702  16.110  -28.499 1.00 66.79  ? 48  MET H CB  1 
ATOM   352  C CG  . MET A 1 49  ? -10.028 14.688  -28.948 1.00 69.35  ? 48  MET H CG  1 
ATOM   353  S SD  . MET A 1 49  ? -9.130  13.418  -28.051 1.00 71.69  ? 48  MET H SD  1 
ATOM   354  C CE  . MET A 1 49  ? -7.475  14.057  -28.198 1.00 65.76  ? 48  MET H CE  1 
ATOM   355  N N   . GLY A 1 50  ? -9.118  18.936  -29.740 1.00 79.88  ? 49  GLY H N   1 
ATOM   356  C CA  . GLY A 1 50  ? -8.561  20.272  -29.623 1.00 81.29  ? 49  GLY H CA  1 
ATOM   357  C C   . GLY A 1 50  ? -7.576  20.557  -30.733 1.00 80.15  ? 49  GLY H C   1 
ATOM   358  O O   . GLY A 1 50  ? -7.291  19.704  -31.579 1.00 80.36  ? 49  GLY H O   1 
ATOM   359  N N   . SER A 1 51  ? -7.040  21.778  -30.702 1.00 81.37  ? 50  SER H N   1 
ATOM   360  C CA  . SER A 1 51  ? -6.123  22.252  -31.730 1.00 85.00  ? 50  SER H CA  1 
ATOM   361  C C   . SER A 1 51  ? -5.129  23.228  -31.118 1.00 87.34  ? 50  SER H C   1 
ATOM   362  O O   . SER A 1 51  ? -5.482  24.021  -30.242 1.00 91.95  ? 50  SER H O   1 
ATOM   363  C CB  . SER A 1 51  ? -6.876  22.934  -32.878 1.00 83.45  ? 50  SER H CB  1 
ATOM   364  O OG  . SER A 1 51  ? -7.962  22.140  -33.321 1.00 83.63  ? 50  SER H OG  1 
ATOM   365  N N   . ILE A 1 52  ? -3.887  23.155  -31.587 1.00 85.37  ? 51  ILE H N   1 
ATOM   366  C CA  . ILE A 1 52  ? -2.858  24.146  -31.298 1.00 90.43  ? 51  ILE H CA  1 
ATOM   367  C C   . ILE A 1 52  ? -2.305  24.694  -32.608 1.00 91.86  ? 51  ILE H C   1 
ATOM   368  O O   . ILE A 1 52  ? -2.230  23.987  -33.621 1.00 89.48  ? 51  ILE H O   1 
ATOM   369  C CB  . ILE A 1 52  ? -1.728  23.570  -30.415 1.00 90.18  ? 51  ILE H CB  1 
ATOM   370  C CG1 . ILE A 1 52  ? -0.800  24.689  -29.938 1.00 92.14  ? 51  ILE H CG1 1 
ATOM   371  C CG2 . ILE A 1 52  ? -0.928  22.525  -31.176 1.00 86.82  ? 51  ILE H CG2 1 
ATOM   372  C CD1 . ILE A 1 52  ? 0.246   24.231  -28.955 1.00 91.45  ? 51  ILE H CD1 1 
ATOM   373  N N   . ASN A 1 53  ? -1.963  25.981  -32.595 1.00 95.09  ? 52  ASN H N   1 
ATOM   374  C CA  . ASN A 1 53  ? -1.429  26.655  -33.774 1.00 91.21  ? 52  ASN H CA  1 
ATOM   375  C C   . ASN A 1 53  ? 0.064   26.382  -33.912 1.00 93.30  ? 52  ASN H C   1 
ATOM   376  O O   . ASN A 1 53  ? 0.893   27.123  -33.382 1.00 94.19  ? 52  ASN H O   1 
ATOM   377  C CB  . ASN A 1 53  ? -1.671  28.164  -33.696 1.00 92.60  ? 52  ASN H CB  1 
ATOM   378  C CG  . ASN A 1 53  ? -1.283  28.885  -34.974 1.00 94.52  ? 52  ASN H CG  1 
ATOM   379  O OD1 . ASN A 1 53  ? -1.412  28.343  -36.071 1.00 99.83  ? 52  ASN H OD1 1 
ATOM   380  N ND2 . ASN A 1 53  ? -0.788  30.110  -34.835 1.00 91.01  ? 52  ASN H ND2 1 
ATOM   381  N N   . TYR A 1 60  ? -10.267 24.165  -27.492 1.00 78.88  ? 59  TYR H N   1 
ATOM   382  C CA  . TYR A 1 60  ? -10.555 22.803  -27.061 1.00 78.49  ? 59  TYR H CA  1 
ATOM   383  C C   . TYR A 1 60  ? -12.048 22.501  -27.118 1.00 79.38  ? 59  TYR H C   1 
ATOM   384  O O   . TYR A 1 60  ? -12.878 23.408  -27.069 1.00 75.80  ? 59  TYR H O   1 
ATOM   385  C CB  . TYR A 1 60  ? -10.040 22.565  -25.640 1.00 75.15  ? 59  TYR H CB  1 
ATOM   386  C CG  . TYR A 1 60  ? -8.537  22.638  -25.497 1.00 72.73  ? 59  TYR H CG  1 
ATOM   387  C CD1 . TYR A 1 60  ? -7.723  21.633  -26.003 1.00 75.51  ? 59  TYR H CD1 1 
ATOM   388  C CD2 . TYR A 1 60  ? -7.933  23.705  -24.845 1.00 75.93  ? 59  TYR H CD2 1 
ATOM   389  C CE1 . TYR A 1 60  ? -6.351  21.690  -25.865 1.00 78.17  ? 59  TYR H CE1 1 
ATOM   390  C CE2 . TYR A 1 60  ? -6.560  23.772  -24.706 1.00 76.83  ? 59  TYR H CE2 1 
ATOM   391  C CZ  . TYR A 1 60  ? -5.774  22.762  -25.218 1.00 80.10  ? 59  TYR H CZ  1 
ATOM   392  O OH  . TYR A 1 60  ? -4.407  22.821  -25.082 1.00 79.85  ? 59  TYR H OH  1 
ATOM   393  N N   . ASN A 1 61  ? -12.377 21.221  -27.222 1.00 78.20  ? 60  ASN H N   1 
ATOM   394  C CA  . ASN A 1 61  ? -13.771 20.800  -27.183 1.00 81.29  ? 60  ASN H CA  1 
ATOM   395  C C   . ASN A 1 61  ? -14.299 20.968  -25.762 1.00 85.39  ? 60  ASN H C   1 
ATOM   396  O O   . ASN A 1 61  ? -13.663 20.493  -24.813 1.00 86.31  ? 60  ASN H O   1 
ATOM   397  C CB  . ASN A 1 61  ? -13.888 19.346  -27.646 1.00 78.29  ? 60  ASN H CB  1 
ATOM   398  C CG  . ASN A 1 61  ? -15.296 18.971  -28.084 1.00 82.10  ? 60  ASN H CG  1 
ATOM   399  O OD1 . ASN A 1 61  ? -16.284 19.384  -27.482 1.00 88.18  ? 60  ASN H OD1 1 
ATOM   400  N ND2 . ASN A 1 61  ? -15.387 18.185  -29.150 1.00 78.58  ? 60  ASN H ND2 1 
ATOM   401  N N   . PRO A 1 62  ? -15.435 21.646  -25.569 1.00 86.20  ? 61  PRO H N   1 
ATOM   402  C CA  . PRO A 1 62  ? -15.976 21.792  -24.206 1.00 85.35  ? 61  PRO H CA  1 
ATOM   403  C C   . PRO A 1 62  ? -16.216 20.476  -23.485 1.00 88.25  ? 61  PRO H C   1 
ATOM   404  O O   . PRO A 1 62  ? -16.193 20.453  -22.248 1.00 91.13  ? 61  PRO H O   1 
ATOM   405  C CB  . PRO A 1 62  ? -17.280 22.571  -24.430 1.00 85.67  ? 61  PRO H CB  1 
ATOM   406  C CG  . PRO A 1 62  ? -17.632 22.352  -25.860 1.00 83.16  ? 61  PRO H CG  1 
ATOM   407  C CD  . PRO A 1 62  ? -16.319 22.249  -26.581 1.00 82.72  ? 61  PRO H CD  1 
ATOM   408  N N   . SER A 1 63  ? -16.467 19.384  -24.210 1.00 86.81  ? 62  SER H N   1 
ATOM   409  C CA  . SER A 1 63  ? -16.664 18.096  -23.553 1.00 85.69  ? 62  SER H CA  1 
ATOM   410  C C   . SER A 1 63  ? -15.431 17.630  -22.783 1.00 86.78  ? 62  SER H C   1 
ATOM   411  O O   . SER A 1 63  ? -15.559 16.779  -21.897 1.00 92.41  ? 62  SER H O   1 
ATOM   412  C CB  . SER A 1 63  ? -17.056 17.036  -24.584 1.00 84.48  ? 62  SER H CB  1 
ATOM   413  O OG  . SER A 1 63  ? -15.930 16.616  -25.339 1.00 87.10  ? 62  SER H OG  1 
ATOM   414  N N   . LEU A 1 64  ? -14.243 18.161  -23.095 1.00 82.53  ? 63  LEU H N   1 
ATOM   415  C CA  . LEU A 1 64  ? -13.010 17.712  -22.456 1.00 86.77  ? 63  LEU H CA  1 
ATOM   416  C C   . LEU A 1 64  ? -12.091 18.846  -22.010 1.00 88.24  ? 63  LEU H C   1 
ATOM   417  O O   . LEU A 1 64  ? -10.949 18.572  -21.622 1.00 86.56  ? 63  LEU H O   1 
ATOM   418  C CB  . LEU A 1 64  ? -12.230 16.772  -23.383 1.00 85.91  ? 63  LEU H CB  1 
ATOM   419  C CG  . LEU A 1 64  ? -12.916 15.461  -23.762 1.00 86.67  ? 63  LEU H CG  1 
ATOM   420  C CD1 . LEU A 1 64  ? -12.082 14.698  -24.778 1.00 82.07  ? 63  LEU H CD1 1 
ATOM   421  C CD2 . LEU A 1 64  ? -13.176 14.622  -22.523 1.00 81.75  ? 63  LEU H CD2 1 
ATOM   422  N N   . LYS A 1 65  ? -12.543 20.102  -22.052 1.00 89.46  ? 64  LYS H N   1 
ATOM   423  C CA  . LYS A 1 65  ? -11.635 21.227  -21.830 1.00 92.38  ? 64  LYS H CA  1 
ATOM   424  C C   . LYS A 1 65  ? -10.995 21.214  -20.443 1.00 90.70  ? 64  LYS H C   1 
ATOM   425  O O   . LYS A 1 65  ? -9.912  21.784  -20.269 1.00 85.88  ? 64  LYS H O   1 
ATOM   426  C CB  . LYS A 1 65  ? -12.374 22.550  -22.062 1.00 95.69  ? 64  LYS H CB  1 
ATOM   427  C CG  . LYS A 1 65  ? -11.513 23.794  -21.865 1.00 97.35  ? 64  LYS H CG  1 
ATOM   428  C CD  . LYS A 1 65  ? -12.251 25.073  -22.224 1.00 99.01  ? 64  LYS H CD  1 
ATOM   429  C CE  . LYS A 1 65  ? -12.491 25.168  -23.721 1.00 91.14  ? 64  LYS H CE  1 
ATOM   430  N NZ  . LYS A 1 65  ? -13.097 26.472  -24.104 1.00 97.80  ? 64  LYS H NZ  1 
ATOM   431  N N   . ASP A 1 66  ? -11.610 20.553  -19.465 1.00 88.40  ? 65  ASP H N   1 
ATOM   432  C CA  . ASP A 1 66  ? -11.090 20.584  -18.103 1.00 85.64  ? 65  ASP H CA  1 
ATOM   433  C C   . ASP A 1 66  ? -9.887  19.672  -17.890 1.00 84.95  ? 65  ASP H C   1 
ATOM   434  O O   . ASP A 1 66  ? -9.226  19.789  -16.853 1.00 80.20  ? 65  ASP H O   1 
ATOM   435  C CB  . ASP A 1 66  ? -12.195 20.225  -17.107 1.00 90.25  ? 65  ASP H CB  1 
ATOM   436  C CG  . ASP A 1 66  ? -12.732 21.440  -16.375 1.00 93.03  ? 65  ASP H CG  1 
ATOM   437  O OD1 . ASP A 1 66  ? -11.916 22.280  -15.938 1.00 89.81  ? 65  ASP H OD1 1 
ATOM   438  O OD2 . ASP A 1 66  ? -13.967 21.560  -16.241 1.00 92.32  ? 65  ASP H OD2 1 
ATOM   439  N N   . ARG A 1 67  ? -9.581  18.771  -18.833 1.00 86.28  ? 66  ARG H N   1 
ATOM   440  C CA  . ARG A 1 67  ? -8.505  17.811  -18.616 1.00 80.71  ? 66  ARG H CA  1 
ATOM   441  C C   . ARG A 1 67  ? -7.660  17.584  -19.867 1.00 78.32  ? 66  ARG H C   1 
ATOM   442  O O   . ARG A 1 67  ? -7.006  16.540  -19.981 1.00 80.67  ? 66  ARG H O   1 
ATOM   443  C CB  . ARG A 1 67  ? -9.047  16.459  -18.137 1.00 74.19  ? 66  ARG H CB  1 
ATOM   444  C CG  . ARG A 1 67  ? -10.222 15.925  -18.938 1.00 76.78  ? 66  ARG H CG  1 
ATOM   445  C CD  . ARG A 1 67  ? -10.645 14.561  -18.415 1.00 67.41  ? 66  ARG H CD  1 
ATOM   446  N NE  . ARG A 1 67  ? -11.533 13.857  -19.332 1.00 68.80  ? 66  ARG H NE  1 
ATOM   447  C CZ  . ARG A 1 67  ? -11.234 12.709  -19.926 1.00 59.48  ? 66  ARG H CZ  1 
ATOM   448  N NH1 . ARG A 1 67  ? -10.074 12.107  -19.722 1.00 58.05  ? 66  ARG H NH1 1 
ATOM   449  N NH2 . ARG A 1 67  ? -12.126 12.146  -20.736 1.00 58.06  ? 66  ARG H NH2 1 
ATOM   450  N N   . ILE A 1 68  ? -7.657  18.526  -20.803 1.00 79.71  ? 67  ILE H N   1 
ATOM   451  C CA  . ILE A 1 68  ? -6.942  18.356  -22.060 1.00 76.47  ? 67  ILE H CA  1 
ATOM   452  C C   . ILE A 1 68  ? -5.745  19.298  -22.142 1.00 73.84  ? 67  ILE H C   1 
ATOM   453  O O   . ILE A 1 68  ? -5.747  20.377  -21.550 1.00 76.05  ? 67  ILE H O   1 
ATOM   454  C CB  . ILE A 1 68  ? -7.882  18.578  -23.252 1.00 77.71  ? 67  ILE H CB  1 
ATOM   455  C CG1 . ILE A 1 68  ? -7.125  18.395  -24.569 1.00 76.80  ? 67  ILE H CG1 1 
ATOM   456  C CG2 . ILE A 1 68  ? -8.532  19.953  -23.158 1.00 80.38  ? 67  ILE H CG2 1 
ATOM   457  C CD1 . ILE A 1 68  ? -7.943  17.743  -25.661 1.00 73.43  ? 67  ILE H CD1 1 
ATOM   458  N N   . ILE A 1 70  ? -2.805  20.490  -24.819 1.00 80.72  ? 69  ILE H N   1 
ATOM   459  C CA  . ILE A 1 70  ? -2.065  20.375  -26.069 1.00 84.12  ? 69  ILE H CA  1 
ATOM   460  C C   . ILE A 1 70  ? -0.945  21.409  -26.114 1.00 89.78  ? 69  ILE H C   1 
ATOM   461  O O   . ILE A 1 70  ? -1.197  22.614  -26.082 1.00 91.56  ? 69  ILE H O   1 
ATOM   462  C CB  . ILE A 1 70  ? -2.994  20.520  -27.285 1.00 84.32  ? 69  ILE H CB  1 
ATOM   463  C CG1 . ILE A 1 70  ? -4.086  19.449  -27.256 1.00 79.82  ? 69  ILE H CG1 1 
ATOM   464  C CG2 . ILE A 1 70  ? -2.198  20.409  -28.571 1.00 84.34  ? 69  ILE H CG2 1 
ATOM   465  C CD1 . ILE A 1 70  ? -5.049  19.530  -28.422 1.00 78.06  ? 69  ILE H CD1 1 
ATOM   466  N N   . THR A 1 71  ? 0.291   20.931  -26.190 1.00 88.34  ? 70  THR H N   1 
ATOM   467  C CA  . THR A 1 71  ? 1.483   21.769  -26.203 1.00 88.20  ? 70  THR H CA  1 
ATOM   468  C C   . THR A 1 71  ? 2.225   21.581  -27.524 1.00 88.99  ? 70  THR H C   1 
ATOM   469  O O   . THR A 1 71  ? 1.771   20.870  -28.424 1.00 87.70  ? 70  THR H O   1 
ATOM   470  C CB  . THR A 1 71  ? 2.391   21.448  -25.013 1.00 90.71  ? 70  THR H CB  1 
ATOM   471  O OG1 . THR A 1 71  ? 2.821   20.083  -25.091 1.00 88.96  ? 70  THR H OG1 1 
ATOM   472  C CG2 . THR A 1 71  ? 1.650   21.668  -23.702 1.00 86.06  ? 70  THR H CG2 1 
ATOM   473  N N   . ARG A 1 72  ? 3.383   22.230  -27.636 1.00 92.87  ? 71  ARG H N   1 
ATOM   474  C CA  . ARG A 1 72  ? 4.148   22.207  -28.873 1.00 92.01  ? 71  ARG H CA  1 
ATOM   475  C C   . ARG A 1 72  ? 5.624   22.426  -28.575 1.00 92.71  ? 71  ARG H C   1 
ATOM   476  O O   . ARG A 1 72  ? 5.987   23.062  -27.582 1.00 95.95  ? 71  ARG H O   1 
ATOM   477  C CB  . ARG A 1 72  ? 3.609   23.267  -29.845 1.00 89.73  ? 71  ARG H CB  1 
ATOM   478  C CG  . ARG A 1 72  ? 3.873   24.707  -29.414 1.00 93.22  ? 71  ARG H CG  1 
ATOM   479  C CD  . ARG A 1 72  ? 3.289   25.704  -30.408 1.00 97.05  ? 71  ARG H CD  1 
ATOM   480  N NE  . ARG A 1 72  ? 3.449   27.084  -29.961 1.00 95.30  ? 71  ARG H NE  1 
ATOM   481  C CZ  . ARG A 1 72  ? 3.066   28.146  -30.656 1.00 94.89  ? 71  ARG H CZ  1 
ATOM   482  N NH1 . ARG A 1 72  ? 2.487   28.027  -31.840 1.00 93.92  ? 71  ARG H NH1 1 
ATOM   483  N NH2 . ARG A 1 72  ? 3.259   29.360  -30.146 1.00 94.65  ? 71  ARG H NH2 1 
ATOM   484  N N   . ASP A 1 73  ? 6.470   21.883  -29.450 1.00 90.52  ? 72  ASP H N   1 
ATOM   485  C CA  . ASP A 1 73  ? 7.918   22.050  -29.368 1.00 93.47  ? 72  ASP H CA  1 
ATOM   486  C C   . ASP A 1 73  ? 8.469   22.239  -30.773 1.00 96.96  ? 72  ASP H C   1 
ATOM   487  O O   . ASP A 1 73  ? 8.297   21.366  -31.628 1.00 96.64  ? 72  ASP H O   1 
ATOM   488  C CB  . ASP A 1 73  ? 8.580   20.849  -28.686 1.00 93.62  ? 72  ASP H CB  1 
ATOM   489  C CG  . ASP A 1 73  ? 10.092  20.947  -28.672 1.00 96.45  ? 72  ASP H CG  1 
ATOM   490  O OD1 . ASP A 1 73  ? 10.632  21.669  -27.808 1.00 99.88  ? 72  ASP H OD1 1 
ATOM   491  O OD2 . ASP A 1 73  ? 10.739  20.306  -29.525 1.00 95.31  ? 72  ASP H OD2 1 
ATOM   492  N N   . THR A 1 74  ? 9.126   23.372  -31.010 1.00 98.42  ? 73  THR H N   1 
ATOM   493  C CA  . THR A 1 74  ? 9.583   23.738  -32.345 1.00 94.94  ? 73  THR H CA  1 
ATOM   494  C C   . THR A 1 74  ? 10.962  23.190  -32.697 1.00 94.45  ? 73  THR H C   1 
ATOM   495  O O   . THR A 1 74  ? 11.336  23.226  -33.874 1.00 94.94  ? 73  THR H O   1 
ATOM   496  C CB  . THR A 1 74  ? 9.603   25.263  -32.496 1.00 95.79  ? 73  THR H CB  1 
ATOM   497  O OG1 . THR A 1 74  ? 10.614  25.817  -31.645 1.00 100.28 ? 73  THR H OG1 1 
ATOM   498  C CG2 . THR A 1 74  ? 8.251   25.855  -32.124 1.00 91.77  ? 73  THR H CG2 1 
ATOM   499  N N   . SER A 1 75  ? 11.728  22.693  -31.721 1.00 95.96  ? 74  SER H N   1 
ATOM   500  C CA  . SER A 1 75  ? 13.062  22.185  -32.029 1.00 97.18  ? 74  SER H CA  1 
ATOM   501  C C   . SER A 1 75  ? 13.007  20.926  -32.888 1.00 97.96  ? 74  SER H C   1 
ATOM   502  O O   . SER A 1 75  ? 13.801  20.774  -33.824 1.00 93.56  ? 74  SER H O   1 
ATOM   503  C CB  . SER A 1 75  ? 13.830  21.912  -30.736 1.00 91.94  ? 74  SER H CB  1 
ATOM   504  O OG  . SER A 1 75  ? 13.996  23.098  -29.979 1.00 83.79  ? 74  SER H OG  1 
ATOM   505  N N   . LYS A 1 76  ? 12.084  20.013  -32.591 1.00 99.32  ? 75  LYS H N   1 
ATOM   506  C CA  . LYS A 1 76  ? 11.905  18.802  -33.382 1.00 95.71  ? 75  LYS H CA  1 
ATOM   507  C C   . LYS A 1 76  ? 10.645  18.836  -34.238 1.00 93.99  ? 75  LYS H C   1 
ATOM   508  O O   . LYS A 1 76  ? 10.321  17.834  -34.886 1.00 92.64  ? 75  LYS H O   1 
ATOM   509  C CB  . LYS A 1 76  ? 11.907  17.567  -32.479 1.00 95.63  ? 75  LYS H CB  1 
ATOM   510  C CG  . LYS A 1 76  ? 13.185  17.410  -31.668 1.00 93.37  ? 75  LYS H CG  1 
ATOM   511  C CD  . LYS A 1 76  ? 13.166  16.149  -30.819 1.00 91.75  ? 75  LYS H CD  1 
ATOM   512  C CE  . LYS A 1 76  ? 14.580  15.724  -30.444 1.00 90.23  ? 75  LYS H CE  1 
ATOM   513  N NZ  . LYS A 1 76  ? 14.599  14.438  -29.694 1.00 77.14  ? 75  LYS H NZ  1 
ATOM   514  N N   . ASN A 1 77  ? 9.929   19.962  -34.253 1.00 94.03  ? 76  ASN H N   1 
ATOM   515  C CA  . ASN A 1 77  ? 8.711   20.133  -35.046 1.00 93.61  ? 76  ASN H CA  1 
ATOM   516  C C   . ASN A 1 77  ? 7.662   19.080  -34.679 1.00 93.12  ? 76  ASN H C   1 
ATOM   517  O O   . ASN A 1 77  ? 7.201   18.295  -35.511 1.00 88.74  ? 76  ASN H O   1 
ATOM   518  C CB  . ASN A 1 77  ? 9.022   20.109  -36.547 1.00 91.77  ? 76  ASN H CB  1 
ATOM   519  C CG  . ASN A 1 77  ? 7.944   20.779  -37.374 1.00 90.60  ? 76  ASN H CG  1 
ATOM   520  O OD1 . ASN A 1 77  ? 7.248   21.675  -36.897 1.00 89.63  ? 76  ASN H OD1 1 
ATOM   521  N ND2 . ASN A 1 77  ? 7.797   20.344  -38.619 1.00 91.06  ? 76  ASN H ND2 1 
ATOM   522  N N   . GLN A 1 78  ? 7.297   19.080  -33.400 1.00 95.63  ? 77  GLN H N   1 
ATOM   523  C CA  . GLN A 1 78  ? 6.347   18.131  -32.843 1.00 88.84  ? 77  GLN H CA  1 
ATOM   524  C C   . GLN A 1 78  ? 5.321   18.885  -32.010 1.00 88.88  ? 77  GLN H C   1 
ATOM   525  O O   . GLN A 1 78  ? 5.623   19.932  -31.430 1.00 93.30  ? 77  GLN H O   1 
ATOM   526  C CB  . GLN A 1 78  ? 7.053   17.081  -31.967 1.00 85.01  ? 77  GLN H CB  1 
ATOM   527  C CG  . GLN A 1 78  ? 7.990   16.143  -32.718 1.00 85.17  ? 77  GLN H CG  1 
ATOM   528  C CD  . GLN A 1 78  ? 8.828   15.289  -31.783 1.00 83.98  ? 77  GLN H CD  1 
ATOM   529  O OE1 . GLN A 1 78  ? 8.978   15.606  -30.603 1.00 84.60  ? 77  GLN H OE1 1 
ATOM   530  N NE2 . GLN A 1 78  ? 9.379   14.201  -32.308 1.00 82.68  ? 77  GLN H NE2 1 
ATOM   531  N N   . PHE A 1 79  ? 4.103   18.347  -31.947 1.00 86.75  ? 78  PHE H N   1 
ATOM   532  C CA  . PHE A 1 79  ? 3.098   18.849  -31.021 1.00 88.33  ? 78  PHE H CA  1 
ATOM   533  C C   . PHE A 1 79  ? 2.465   17.668  -30.299 1.00 85.79  ? 78  PHE H C   1 
ATOM   534  O O   . PHE A 1 79  ? 2.339   16.573  -30.853 1.00 84.60  ? 78  PHE H O   1 
ATOM   535  C CB  . PHE A 1 79  ? 2.026   19.712  -31.722 1.00 87.07  ? 78  PHE H CB  1 
ATOM   536  C CG  . PHE A 1 79  ? 1.064   18.939  -32.579 1.00 87.29  ? 78  PHE H CG  1 
ATOM   537  C CD1 . PHE A 1 79  ? 1.445   18.447  -33.816 1.00 85.60  ? 78  PHE H CD1 1 
ATOM   538  C CD2 . PHE A 1 79  ? -0.243  18.747  -32.162 1.00 85.12  ? 78  PHE H CD2 1 
ATOM   539  C CE1 . PHE A 1 79  ? 0.547   17.754  -34.606 1.00 81.08  ? 78  PHE H CE1 1 
ATOM   540  C CE2 . PHE A 1 79  ? -1.144  18.056  -32.947 1.00 81.39  ? 78  PHE H CE2 1 
ATOM   541  C CZ  . PHE A 1 79  ? -0.749  17.559  -34.170 1.00 82.92  ? 78  PHE H CZ  1 
ATOM   542  N N   . PHE A 1 80  ? 2.063   17.906  -29.053 1.00 88.77  ? 79  PHE H N   1 
ATOM   543  C CA  . PHE A 1 80  ? 1.785   16.836  -28.108 1.00 85.55  ? 79  PHE H CA  1 
ATOM   544  C C   . PHE A 1 80  ? 0.394   16.979  -27.511 1.00 82.75  ? 79  PHE H C   1 
ATOM   545  O O   . PHE A 1 80  ? -0.156  18.079  -27.417 1.00 80.81  ? 79  PHE H O   1 
ATOM   546  C CB  . PHE A 1 80  ? 2.829   16.822  -26.985 1.00 79.64  ? 79  PHE H CB  1 
ATOM   547  C CG  . PHE A 1 80  ? 4.225   17.099  -27.461 1.00 85.47  ? 79  PHE H CG  1 
ATOM   548  C CD1 . PHE A 1 80  ? 5.028   16.074  -27.930 1.00 86.99  ? 79  PHE H CD1 1 
ATOM   549  C CD2 . PHE A 1 80  ? 4.733   18.387  -27.444 1.00 84.84  ? 79  PHE H CD2 1 
ATOM   550  C CE1 . PHE A 1 80  ? 6.312   16.327  -28.372 1.00 84.88  ? 79  PHE H CE1 1 
ATOM   551  C CE2 . PHE A 1 80  ? 6.014   18.646  -27.885 1.00 89.55  ? 79  PHE H CE2 1 
ATOM   552  C CZ  . PHE A 1 80  ? 6.806   17.615  -28.349 1.00 89.94  ? 79  PHE H CZ  1 
ATOM   553  N N   . LEU A 1 81  ? -0.166  15.841  -27.111 1.00 79.66  ? 80  LEU H N   1 
ATOM   554  C CA  . LEU A 1 81  ? -1.462  15.767  -26.455 1.00 74.87  ? 80  LEU H CA  1 
ATOM   555  C C   . LEU A 1 81  ? -1.287  15.268  -25.028 1.00 68.81  ? 80  LEU H C   1 
ATOM   556  O O   . LEU A 1 81  ? -0.530  14.324  -24.779 1.00 71.21  ? 80  LEU H O   1 
ATOM   557  C CB  . LEU A 1 81  ? -2.406  14.839  -27.215 1.00 68.67  ? 80  LEU H CB  1 
ATOM   558  C CG  . LEU A 1 81  ? -3.708  14.503  -26.491 1.00 68.10  ? 80  LEU H CG  1 
ATOM   559  C CD1 . LEU A 1 81  ? -4.710  15.640  -26.634 1.00 69.43  ? 80  LEU H CD1 1 
ATOM   560  C CD2 . LEU A 1 81  ? -4.270  13.186  -27.001 1.00 67.84  ? 80  LEU H CD2 1 
ATOM   561  N N   . LYS A 1 82  ? -1.991  15.904  -24.093 1.00 70.62  ? 81  LYS H N   1 
ATOM   562  C CA  . LYS A 1 82  ? -1.993  15.499  -22.691 1.00 71.80  ? 81  LYS H CA  1 
ATOM   563  C C   . LYS A 1 82  ? -3.430  15.362  -22.215 1.00 70.70  ? 81  LYS H C   1 
ATOM   564  O O   . LYS A 1 82  ? -4.163  16.355  -22.161 1.00 73.47  ? 81  LYS H O   1 
ATOM   565  C CB  . LYS A 1 82  ? -1.238  16.514  -21.828 1.00 71.65  ? 81  LYS H CB  1 
ATOM   566  C CG  . LYS A 1 82  ? 0.212   16.158  -21.559 1.00 70.25  ? 81  LYS H CG  1 
ATOM   567  C CD  . LYS A 1 82  ? 0.335   15.278  -20.328 1.00 74.58  ? 81  LYS H CD  1 
ATOM   568  C CE  . LYS A 1 82  ? -0.216  15.979  -19.097 1.00 78.31  ? 81  LYS H CE  1 
ATOM   569  N NZ  . LYS A 1 82  ? -0.051  15.157  -17.867 1.00 80.13  ? 81  LYS H NZ  1 
ATOM   570  N N   . LEU A 1 83  ? -3.834  14.138  -21.877 1.00 72.20  ? 82  LEU H N   1 
ATOM   571  C CA  . LEU A 1 83  ? -5.170  13.859  -21.358 1.00 73.67  ? 82  LEU H CA  1 
ATOM   572  C C   . LEU A 1 83  ? -5.033  13.187  -19.995 1.00 72.60  ? 82  LEU H C   1 
ATOM   573  O O   . LEU A 1 83  ? -4.548  12.055  -19.904 1.00 72.99  ? 82  LEU H O   1 
ATOM   574  C CB  . LEU A 1 83  ? -5.957  12.976  -22.327 1.00 65.98  ? 82  LEU H CB  1 
ATOM   575  C CG  . LEU A 1 83  ? -7.460  12.834  -22.070 1.00 66.57  ? 82  LEU H CG  1 
ATOM   576  C CD1 . LEU A 1 83  ? -8.213  13.996  -22.704 1.00 64.82  ? 82  LEU H CD1 1 
ATOM   577  C CD2 . LEU A 1 83  ? -7.989  11.503  -22.583 1.00 64.84  ? 82  LEU H CD2 1 
ATOM   578  N N   . ASN A 1 84  A -5.456  13.880  -18.943 1.00 74.03  ? 82  ASN H N   1 
ATOM   579  C CA  . ASN A 1 84  A -5.322  13.397  -17.575 1.00 75.16  ? 82  ASN H CA  1 
ATOM   580  C C   . ASN A 1 84  A -6.621  12.773  -17.078 1.00 69.52  ? 82  ASN H C   1 
ATOM   581  O O   . ASN A 1 84  A -7.712  13.056  -17.580 1.00 63.16  ? 82  ASN H O   1 
ATOM   582  C CB  . ASN A 1 84  A -4.891  14.516  -16.624 1.00 72.38  ? 82  ASN H CB  1 
ATOM   583  C CG  . ASN A 1 84  A -3.385  14.656  -16.537 1.00 76.71  ? 82  ASN H CG  1 
ATOM   584  O OD1 . ASN A 1 84  A -2.697  13.747  -16.070 1.00 80.28  ? 82  ASN H OD1 1 
ATOM   585  N ND2 . ASN A 1 84  A -2.865  15.793  -16.978 1.00 78.43  ? 82  ASN H ND2 1 
ATOM   586  N N   . SER A 1 85  B -6.479  11.918  -16.067 1.00 69.11  ? 82  SER H N   1 
ATOM   587  C CA  . SER A 1 85  B -7.596  11.251  -15.401 1.00 68.50  ? 82  SER H CA  1 
ATOM   588  C C   . SER A 1 85  B -8.458  10.494  -16.410 1.00 65.39  ? 82  SER H C   1 
ATOM   589  O O   . SER A 1 85  B -9.646  10.764  -16.595 1.00 61.15  ? 82  SER H O   1 
ATOM   590  C CB  . SER A 1 85  B -8.429  12.255  -14.599 1.00 70.91  ? 82  SER H CB  1 
ATOM   591  O OG  . SER A 1 85  B -7.628  12.931  -13.645 1.00 73.24  ? 82  SER H OG  1 
ATOM   592  N N   . VAL A 1 86  C -7.826  9.529   -17.066 1.00 67.50  ? 82  VAL H N   1 
ATOM   593  C CA  . VAL A 1 86  C -8.480  8.758   -18.115 1.00 64.50  ? 82  VAL H CA  1 
ATOM   594  C C   . VAL A 1 86  C -9.356  7.677   -17.497 1.00 59.82  ? 82  VAL H C   1 
ATOM   595  O O   . VAL A 1 86  C -9.064  7.140   -16.422 1.00 56.90  ? 82  VAL H O   1 
ATOM   596  C CB  . VAL A 1 86  C -7.435  8.157   -19.076 1.00 57.83  ? 82  VAL H CB  1 
ATOM   597  C CG1 . VAL A 1 86  C -6.696  9.264   -19.811 1.00 62.46  ? 82  VAL H CG1 1 
ATOM   598  C CG2 . VAL A 1 86  C -6.456  7.283   -18.312 1.00 58.62  ? 82  VAL H CG2 1 
ATOM   599  N N   . THR A 1 87  ? -10.450 7.363   -18.181 1.00 58.57  ? 83  THR H N   1 
ATOM   600  C CA  . THR A 1 87  ? -11.337 6.260   -17.838 1.00 58.08  ? 83  THR H CA  1 
ATOM   601  C C   . THR A 1 87  ? -11.393 5.288   -19.014 1.00 58.50  ? 83  THR H C   1 
ATOM   602  O O   . THR A 1 87  ? -10.804 5.526   -20.071 1.00 60.29  ? 83  THR H O   1 
ATOM   603  C CB  . THR A 1 87  ? -12.738 6.769   -17.483 1.00 56.83  ? 83  THR H CB  1 
ATOM   604  O OG1 . THR A 1 87  ? -13.379 7.272   -18.662 1.00 59.18  ? 83  THR H OG1 1 
ATOM   605  C CG2 . THR A 1 87  ? -12.656 7.882   -16.448 1.00 58.73  ? 83  THR H CG2 1 
ATOM   606  N N   . THR A 1 88  ? -12.113 4.179   -18.824 1.00 53.81  ? 84  THR H N   1 
ATOM   607  C CA  . THR A 1 88  ? -12.229 3.192   -19.892 1.00 58.55  ? 84  THR H CA  1 
ATOM   608  C C   . THR A 1 88  ? -12.925 3.755   -21.124 1.00 50.90  ? 84  THR H C   1 
ATOM   609  O O   . THR A 1 88  ? -12.730 3.231   -22.226 1.00 50.11  ? 84  THR H O   1 
ATOM   610  C CB  . THR A 1 88  ? -12.976 1.952   -19.398 1.00 54.11  ? 84  THR H CB  1 
ATOM   611  O OG1 . THR A 1 88  ? -14.294 2.318   -18.971 1.00 58.08  ? 84  THR H OG1 1 
ATOM   612  C CG2 . THR A 1 88  ? -12.227 1.305   -18.246 1.00 46.76  ? 84  THR H CG2 1 
ATOM   613  N N   . GLU A 1 89  ? -13.725 4.811   -20.965 1.00 54.09  ? 85  GLU H N   1 
ATOM   614  C CA  . GLU A 1 89  ? -14.361 5.454   -22.106 1.00 57.17  ? 85  GLU H CA  1 
ATOM   615  C C   . GLU A 1 89  ? -13.368 6.191   -22.996 1.00 52.57  ? 85  GLU H C   1 
ATOM   616  O O   . GLU A 1 89  ? -13.723 6.548   -24.124 1.00 54.62  ? 85  GLU H O   1 
ATOM   617  C CB  . GLU A 1 89  ? -15.444 6.427   -21.631 1.00 63.73  ? 85  GLU H CB  1 
ATOM   618  C CG  . GLU A 1 89  ? -16.765 5.775   -21.239 1.00 61.86  ? 85  GLU H CG  1 
ATOM   619  C CD  . GLU A 1 89  ? -16.663 4.938   -19.978 1.00 72.44  ? 85  GLU H CD  1 
ATOM   620  O OE1 . GLU A 1 89  ? -16.584 3.697   -20.089 1.00 72.94  ? 85  GLU H OE1 1 
ATOM   621  O OE2 . GLU A 1 89  ? -16.659 5.523   -18.875 1.00 75.11  ? 85  GLU H OE2 1 
ATOM   622  N N   . ASP A 1 90  ? -12.146 6.427   -22.524 1.00 48.96  ? 86  ASP H N   1 
ATOM   623  C CA  . ASP A 1 90  ? -11.120 7.091   -23.317 1.00 55.63  ? 86  ASP H CA  1 
ATOM   624  C C   . ASP A 1 90  ? -10.346 6.135   -24.217 1.00 56.16  ? 86  ASP H C   1 
ATOM   625  O O   . ASP A 1 90  ? -9.470  6.586   -24.963 1.00 54.32  ? 86  ASP H O   1 
ATOM   626  C CB  . ASP A 1 90  ? -10.149 7.838   -22.398 1.00 53.27  ? 86  ASP H CB  1 
ATOM   627  C CG  . ASP A 1 90  ? -10.807 9.002   -21.682 1.00 56.70  ? 86  ASP H CG  1 
ATOM   628  O OD1 . ASP A 1 90  ? -11.697 9.641   -22.281 1.00 57.78  ? 86  ASP H OD1 1 
ATOM   629  O OD2 . ASP A 1 90  ? -10.439 9.277   -20.523 1.00 59.63  ? 86  ASP H OD2 1 
ATOM   630  N N   . THR A 1 91  ? -10.634 4.836   -24.156 1.00 51.14  ? 87  THR H N   1 
ATOM   631  C CA  . THR A 1 91  ? -10.062 3.885   -25.102 1.00 49.07  ? 87  THR H CA  1 
ATOM   632  C C   . THR A 1 91  ? -10.482 4.246   -26.520 1.00 49.43  ? 87  THR H C   1 
ATOM   633  O O   . THR A 1 91  ? -11.676 4.254   -26.833 1.00 47.62  ? 87  THR H O   1 
ATOM   634  C CB  . THR A 1 91  ? -10.523 2.468   -24.760 1.00 45.19  ? 87  THR H CB  1 
ATOM   635  O OG1 . THR A 1 91  ? -10.087 2.123   -23.439 1.00 46.82  ? 87  THR H OG1 1 
ATOM   636  C CG2 . THR A 1 91  ? -9.956  1.469   -25.756 1.00 45.20  ? 87  THR H CG2 1 
ATOM   637  N N   . ALA A 1 92  ? -9.507  4.528   -27.384 1.00 49.46  ? 88  ALA H N   1 
ATOM   638  C CA  . ALA A 1 92  ? -9.841  5.006   -28.723 1.00 50.78  ? 88  ALA H CA  1 
ATOM   639  C C   . ALA A 1 92  ? -8.590  5.031   -29.590 1.00 46.05  ? 88  ALA H C   1 
ATOM   640  O O   . ALA A 1 92  ? -7.468  4.875   -29.105 1.00 44.00  ? 88  ALA H O   1 
ATOM   641  C CB  . ALA A 1 92  ? -10.481 6.398   -28.679 1.00 54.29  ? 88  ALA H CB  1 
ATOM   642  N N   . THR A 1 93  ? -8.803  5.225   -30.890 1.00 47.04  ? 89  THR H N   1 
ATOM   643  C CA  . THR A 1 93  ? -7.714  5.456   -31.832 1.00 51.62  ? 89  THR H CA  1 
ATOM   644  C C   . THR A 1 93  ? -7.527  6.959   -32.004 1.00 53.59  ? 89  THR H C   1 
ATOM   645  O O   . THR A 1 93  ? -8.465  7.664   -32.389 1.00 53.35  ? 89  THR H O   1 
ATOM   646  C CB  . THR A 1 93  ? -8.006  4.794   -33.177 1.00 55.54  ? 89  THR H CB  1 
ATOM   647  O OG1 . THR A 1 93  ? -8.097  3.374   -33.006 1.00 57.52  ? 89  THR H OG1 1 
ATOM   648  C CG2 . THR A 1 93  ? -6.903  5.111   -34.175 1.00 54.84  ? 89  THR H CG2 1 
ATOM   649  N N   . TYR A 1 94  ? -6.323  7.446   -31.728 1.00 54.93  ? 90  TYR H N   1 
ATOM   650  C CA  . TYR A 1 94  ? -6.031  8.872   -31.749 1.00 57.20  ? 90  TYR H CA  1 
ATOM   651  C C   . TYR A 1 94  ? -5.242  9.228   -33.003 1.00 55.71  ? 90  TYR H C   1 
ATOM   652  O O   . TYR A 1 94  ? -4.261  8.554   -33.341 1.00 53.71  ? 90  TYR H O   1 
ATOM   653  C CB  . TYR A 1 94  ? -5.257  9.283   -30.495 1.00 55.34  ? 90  TYR H CB  1 
ATOM   654  C CG  . TYR A 1 94  ? -6.084  9.234   -29.228 1.00 56.16  ? 90  TYR H CG  1 
ATOM   655  C CD1 . TYR A 1 94  ? -6.430  8.021   -28.644 1.00 56.17  ? 90  TYR H CD1 1 
ATOM   656  C CD2 . TYR A 1 94  ? -6.529  10.400  -28.620 1.00 58.77  ? 90  TYR H CD2 1 
ATOM   657  C CE1 . TYR A 1 94  ? -7.189  7.972   -27.489 1.00 55.59  ? 90  TYR H CE1 1 
ATOM   658  C CE2 . TYR A 1 94  ? -7.289  10.360  -27.464 1.00 61.38  ? 90  TYR H CE2 1 
ATOM   659  C CZ  . TYR A 1 94  ? -7.616  9.144   -26.904 1.00 60.82  ? 90  TYR H CZ  1 
ATOM   660  O OH  . TYR A 1 94  ? -8.371  9.101   -25.754 1.00 56.91  ? 90  TYR H OH  1 
ATOM   661  N N   . TYR A 1 95  ? -5.677  10.284  -33.688 1.00 58.07  ? 91  TYR H N   1 
ATOM   662  C CA  . TYR A 1 95  ? -5.048  10.798  -34.892 1.00 61.00  ? 91  TYR H CA  1 
ATOM   663  C C   . TYR A 1 95  ? -4.629  12.240  -34.651 1.00 61.02  ? 91  TYR H C   1 
ATOM   664  O O   . TYR A 1 95  ? -5.359  13.009  -34.013 1.00 61.59  ? 91  TYR H O   1 
ATOM   665  C CB  . TYR A 1 95  ? -6.010  10.763  -36.092 1.00 60.22  ? 91  TYR H CB  1 
ATOM   666  C CG  . TYR A 1 95  ? -6.565  9.403   -36.453 1.00 57.28  ? 91  TYR H CG  1 
ATOM   667  C CD1 . TYR A 1 95  ? -5.882  8.557   -37.314 1.00 54.90  ? 91  TYR H CD1 1 
ATOM   668  C CD2 . TYR A 1 95  ? -7.788  8.977   -35.951 1.00 59.69  ? 91  TYR H CD2 1 
ATOM   669  C CE1 . TYR A 1 95  ? -6.392  7.317   -37.652 1.00 58.89  ? 91  TYR H CE1 1 
ATOM   670  C CE2 . TYR A 1 95  ? -8.307  7.740   -36.284 1.00 56.73  ? 91  TYR H CE2 1 
ATOM   671  C CZ  . TYR A 1 95  ? -7.605  6.914   -37.136 1.00 57.64  ? 91  TYR H CZ  1 
ATOM   672  O OH  . TYR A 1 95  ? -8.115  5.681   -37.472 1.00 59.43  ? 91  TYR H OH  1 
ATOM   673  N N   . CYS A 1 96  ? -3.453  12.605  -35.145 1.00 64.57  ? 92  CYS H N   1 
ATOM   674  C CA  . CYS A 1 96  ? -3.096  14.007  -35.281 1.00 71.21  ? 92  CYS H CA  1 
ATOM   675  C C   . CYS A 1 96  ? -3.232  14.426  -36.739 1.00 71.41  ? 92  CYS H C   1 
ATOM   676  O O   . CYS A 1 96  ? -2.990  13.637  -37.656 1.00 66.69  ? 92  CYS H O   1 
ATOM   677  C CB  . CYS A 1 96  ? -1.679  14.273  -34.773 1.00 72.42  ? 92  CYS H CB  1 
ATOM   678  S SG  . CYS A 1 96  ? -0.364  13.269  -35.491 1.00 72.06  ? 92  CYS H SG  1 
ATOM   679  N N   . ALA A 1 97  ? -3.626  15.680  -36.948 1.00 71.73  ? 93  ALA H N   1 
ATOM   680  C CA  . ALA A 1 97  ? -3.899  16.148  -38.298 1.00 73.54  ? 93  ALA H CA  1 
ATOM   681  C C   . ALA A 1 97  ? -3.615  17.639  -38.393 1.00 79.20  ? 93  ALA H C   1 
ATOM   682  O O   . ALA A 1 97  ? -3.590  18.352  -37.389 1.00 79.53  ? 93  ALA H O   1 
ATOM   683  C CB  . ALA A 1 97  ? -5.346  15.853  -38.713 1.00 73.05  ? 93  ALA H CB  1 
ATOM   684  N N   . ARG A 1 98  ? -3.381  18.097  -39.619 1.00 80.21  ? 94  ARG H N   1 
ATOM   685  C CA  . ARG A 1 98  ? -3.322  19.521  -39.928 1.00 79.25  ? 94  ARG H CA  1 
ATOM   686  C C   . ARG A 1 98  ? -4.664  19.908  -40.535 1.00 75.41  ? 94  ARG H C   1 
ATOM   687  O O   . ARG A 1 98  ? -5.003  19.464  -41.636 1.00 81.22  ? 94  ARG H O   1 
ATOM   688  C CB  . ARG A 1 98  ? -2.177  19.835  -40.888 1.00 83.61  ? 94  ARG H CB  1 
ATOM   689  C CG  . ARG A 1 98  ? -1.979  21.322  -41.138 1.00 90.11  ? 94  ARG H CG  1 
ATOM   690  C CD  . ARG A 1 98  ? -1.070  21.571  -42.329 1.00 90.58  ? 94  ARG H CD  1 
ATOM   691  N NE  . ARG A 1 98  ? -1.792  21.457  -43.591 1.00 89.26  ? 94  ARG H NE  1 
ATOM   692  C CZ  . ARG A 1 98  ? -1.255  21.669  -44.785 1.00 90.34  ? 94  ARG H CZ  1 
ATOM   693  N NH1 . ARG A 1 98  ? 0.017   22.007  -44.921 1.00 87.93  ? 94  ARG H NH1 1 
ATOM   694  N NH2 . ARG A 1 98  ? -2.013  21.537  -45.870 1.00 88.53  ? 94  ARG H NH2 1 
ATOM   695  N N   . GLY A 1 99  ? -5.419  20.742  -39.823 1.00 79.62  ? 95  GLY H N   1 
ATOM   696  C CA  . GLY A 1 99  ? -6.764  21.079  -40.246 1.00 79.96  ? 95  GLY H CA  1 
ATOM   697  C C   . GLY A 1 99  ? -7.610  19.850  -40.507 1.00 81.88  ? 95  GLY H C   1 
ATOM   698  O O   . GLY A 1 99  ? -8.082  19.200  -39.569 1.00 83.81  ? 95  GLY H O   1 
ATOM   699  N N   . GLY A 1 100 ? -7.806  19.519  -41.781 1.00 77.68  ? 96  GLY H N   1 
ATOM   700  C CA  . GLY A 1 100 ? -8.505  18.304  -42.145 1.00 74.86  ? 96  GLY H CA  1 
ATOM   701  C C   . GLY A 1 100 ? -7.970  17.654  -43.404 1.00 69.89  ? 96  GLY H C   1 
ATOM   702  O O   . GLY A 1 100 ? -8.507  16.640  -43.861 1.00 67.10  ? 96  GLY H O   1 
ATOM   703  N N   . ASP A 1 101 ? -6.907  18.222  -43.975 1.00 76.81  ? 101 ASP H N   1 
ATOM   704  C CA  . ASP A 1 101 ? -6.395  17.747  -45.254 1.00 74.67  ? 101 ASP H CA  1 
ATOM   705  C C   . ASP A 1 101 ? -5.347  16.650  -45.114 1.00 70.42  ? 101 ASP H C   1 
ATOM   706  O O   . ASP A 1 101 ? -5.286  15.755  -45.964 1.00 72.85  ? 101 ASP H O   1 
ATOM   707  C CB  . ASP A 1 101 ? -5.813  18.916  -46.057 1.00 76.39  ? 101 ASP H CB  1 
ATOM   708  C CG  . ASP A 1 101 ? -4.918  19.813  -45.223 1.00 82.44  ? 101 ASP H CG  1 
ATOM   709  O OD1 . ASP A 1 101 ? -4.302  19.318  -44.260 1.00 82.77  ? 101 ASP H OD1 1 
ATOM   710  O OD2 . ASP A 1 101 ? -4.835  21.021  -45.532 1.00 84.40  ? 101 ASP H OD2 1 
ATOM   711  N N   . TYR A 1 102 ? -4.522  16.691  -44.069 1.00 70.07  ? 102 TYR H N   1 
ATOM   712  C CA  . TYR A 1 102 ? -3.475  15.696  -43.863 1.00 72.34  ? 102 TYR H CA  1 
ATOM   713  C C   . TYR A 1 102 ? -3.634  15.089  -42.477 1.00 73.07  ? 102 TYR H C   1 
ATOM   714  O O   . TYR A 1 102 ? -3.541  15.801  -41.472 1.00 67.85  ? 102 TYR H O   1 
ATOM   715  C CB  . TYR A 1 102 ? -2.085  16.319  -44.032 1.00 72.35  ? 102 TYR H CB  1 
ATOM   716  C CG  . TYR A 1 102 ? -1.768  16.711  -45.460 1.00 79.67  ? 102 TYR H CG  1 
ATOM   717  C CD1 . TYR A 1 102 ? -2.135  17.955  -45.957 1.00 79.47  ? 102 TYR H CD1 1 
ATOM   718  C CD2 . TYR A 1 102 ? -1.106  15.837  -46.313 1.00 78.55  ? 102 TYR H CD2 1 
ATOM   719  C CE1 . TYR A 1 102 ? -1.853  18.319  -47.259 1.00 81.11  ? 102 TYR H CE1 1 
ATOM   720  C CE2 . TYR A 1 102 ? -0.818  16.194  -47.620 1.00 83.16  ? 102 TYR H CE2 1 
ATOM   721  C CZ  . TYR A 1 102 ? -1.194  17.436  -48.086 1.00 84.34  ? 102 TYR H CZ  1 
ATOM   722  O OH  . TYR A 1 102 ? -0.911  17.798  -49.383 1.00 81.67  ? 102 TYR H OH  1 
ATOM   723  N N   . TRP A 1 103 ? -3.867  13.780  -42.427 1.00 70.97  ? 103 TRP H N   1 
ATOM   724  C CA  . TRP A 1 103 ? -4.042  13.045  -41.183 1.00 64.68  ? 103 TRP H CA  1 
ATOM   725  C C   . TRP A 1 103 ? -2.847  12.131  -40.936 1.00 60.70  ? 103 TRP H C   1 
ATOM   726  O O   . TRP A 1 103 ? -2.181  11.682  -41.872 1.00 55.33  ? 103 TRP H O   1 
ATOM   727  C CB  . TRP A 1 103 ? -5.324  12.203  -41.207 1.00 56.38  ? 103 TRP H CB  1 
ATOM   728  C CG  . TRP A 1 103 ? -6.606  12.987  -41.312 1.00 63.70  ? 103 TRP H CG  1 
ATOM   729  C CD1 . TRP A 1 103 ? -6.956  13.858  -42.303 1.00 70.84  ? 103 TRP H CD1 1 
ATOM   730  C CD2 . TRP A 1 103 ? -7.726  12.931  -40.416 1.00 64.50  ? 103 TRP H CD2 1 
ATOM   731  N NE1 . TRP A 1 103 ? -8.212  14.364  -42.068 1.00 66.52  ? 103 TRP H NE1 1 
ATOM   732  C CE2 . TRP A 1 103 ? -8.707  13.809  -40.918 1.00 61.31  ? 103 TRP H CE2 1 
ATOM   733  C CE3 . TRP A 1 103 ? -7.990  12.231  -39.233 1.00 58.80  ? 103 TRP H CE3 1 
ATOM   734  C CZ2 . TRP A 1 103 ? -9.930  14.007  -40.279 1.00 60.14  ? 103 TRP H CZ2 1 
ATOM   735  C CZ3 . TRP A 1 103 ? -9.206  12.429  -38.601 1.00 61.96  ? 103 TRP H CZ3 1 
ATOM   736  C CH2 . TRP A 1 103 ? -10.161 13.309  -39.127 1.00 64.33  ? 103 TRP H CH2 1 
ATOM   737  N N   . GLY A 1 104 ? -2.588  11.850  -39.660 1.00 62.20  ? 104 GLY H N   1 
ATOM   738  C CA  . GLY A 1 104 ? -1.599  10.865  -39.274 1.00 57.00  ? 104 GLY H CA  1 
ATOM   739  C C   . GLY A 1 104 ? -2.105  9.436   -39.427 1.00 57.78  ? 104 GLY H C   1 
ATOM   740  O O   . GLY A 1 104 ? -3.234  9.177   -39.843 1.00 56.26  ? 104 GLY H O   1 
ATOM   741  N N   . GLN A 1 105 ? -1.235  8.484   -39.075 1.00 59.53  ? 105 GLN H N   1 
ATOM   742  C CA  . GLN A 1 105 ? -1.607  7.077   -39.194 1.00 57.96  ? 105 GLN H CA  1 
ATOM   743  C C   . GLN A 1 105 ? -2.552  6.648   -38.076 1.00 59.80  ? 105 GLN H C   1 
ATOM   744  O O   . GLN A 1 105 ? -3.360  5.731   -38.267 1.00 55.77  ? 105 GLN H O   1 
ATOM   745  C CB  . GLN A 1 105 ? -0.356  6.189   -39.202 1.00 65.66  ? 105 GLN H CB  1 
ATOM   746  C CG  . GLN A 1 105 ? 0.530   6.357   -40.424 1.00 76.77  ? 105 GLN H CG  1 
ATOM   747  C CD  . GLN A 1 105 ? 1.471   7.539   -40.309 1.00 81.30  ? 105 GLN H CD  1 
ATOM   748  O OE1 . GLN A 1 105 ? 1.540   8.382   -41.203 1.00 84.51  ? 105 GLN H OE1 1 
ATOM   749  N NE2 . GLN A 1 105 ? 2.204   7.605   -39.199 1.00 82.16  ? 105 GLN H NE2 1 
ATOM   750  N N   . GLY A 1 106 ? -2.466  7.283   -36.906 1.00 62.44  ? 106 GLY H N   1 
ATOM   751  C CA  . GLY A 1 106 ? -3.319  6.921   -35.784 1.00 58.05  ? 106 GLY H CA  1 
ATOM   752  C C   . GLY A 1 106 ? -2.732  5.840   -34.894 1.00 55.16  ? 106 GLY H C   1 
ATOM   753  O O   . GLY A 1 106 ? -2.159  4.862   -35.387 1.00 56.04  ? 106 GLY H O   1 
ATOM   754  N N   . THR A 1 107 ? -2.884  5.994   -33.581 1.00 58.88  ? 107 THR H N   1 
ATOM   755  C CA  . THR A 1 107 ? -2.398  5.019   -32.616 1.00 51.95  ? 107 THR H CA  1 
ATOM   756  C C   . THR A 1 107 ? -3.533  4.601   -31.692 1.00 50.17  ? 107 THR H C   1 
ATOM   757  O O   . THR A 1 107 ? -4.317  5.438   -31.238 1.00 49.45  ? 107 THR H O   1 
ATOM   758  C CB  . THR A 1 107 ? -1.223  5.574   -31.797 1.00 52.06  ? 107 THR H CB  1 
ATOM   759  O OG1 . THR A 1 107 ? -0.863  4.635   -30.775 1.00 61.84  ? 107 THR H OG1 1 
ATOM   760  C CG2 . THR A 1 107 ? -1.580  6.910   -31.154 1.00 50.39  ? 107 THR H CG2 1 
ATOM   761  N N   . SER A 1 108 ? -3.628  3.299   -31.437 1.00 46.20  ? 108 SER H N   1 
ATOM   762  C CA  . SER A 1 108 ? -4.670  2.763   -30.571 1.00 50.95  ? 108 SER H CA  1 
ATOM   763  C C   . SER A 1 108 ? -4.242  2.862   -29.112 1.00 44.28  ? 108 SER H C   1 
ATOM   764  O O   . SER A 1 108 ? -3.160  2.394   -28.742 1.00 49.43  ? 108 SER H O   1 
ATOM   765  C CB  . SER A 1 108 ? -4.971  1.311   -30.938 1.00 46.58  ? 108 SER H CB  1 
ATOM   766  O OG  . SER A 1 108 ? -5.915  0.747   -30.046 1.00 60.96  ? 108 SER H OG  1 
ATOM   767  N N   . VAL A 1 109 ? -5.088  3.473   -28.285 1.00 43.19  ? 109 VAL H N   1 
ATOM   768  C CA  . VAL A 1 109 ? -4.837  3.621   -26.857 1.00 47.74  ? 109 VAL H CA  1 
ATOM   769  C C   . VAL A 1 109 ? -5.923  2.864   -26.105 1.00 47.73  ? 109 VAL H C   1 
ATOM   770  O O   . VAL A 1 109 ? -7.119  3.153   -26.267 1.00 48.16  ? 109 VAL H O   1 
ATOM   771  C CB  . VAL A 1 109 ? -4.799  5.096   -26.430 1.00 52.17  ? 109 VAL H CB  1 
ATOM   772  C CG1 . VAL A 1 109 ? -4.697  5.204   -24.916 1.00 52.16  ? 109 VAL H CG1 1 
ATOM   773  C CG2 . VAL A 1 109 ? -3.637  5.809   -27.100 1.00 51.89  ? 109 VAL H CG2 1 
ATOM   774  N N   . THR A 1 110 ? -5.503  1.898   -25.290 1.00 48.04  ? 110 THR H N   1 
ATOM   775  C CA  . THR A 1 110 ? -6.385  1.100   -24.447 1.00 50.49  ? 110 THR H CA  1 
ATOM   776  C C   . THR A 1 110 ? -6.218  1.550   -23.002 1.00 46.45  ? 110 THR H C   1 
ATOM   777  O O   . THR A 1 110 ? -5.106  1.515   -22.463 1.00 48.64  ? 110 THR H O   1 
ATOM   778  C CB  . THR A 1 110 ? -6.068  -0.390  -24.579 1.00 49.21  ? 110 THR H CB  1 
ATOM   779  O OG1 . THR A 1 110 ? -6.284  -0.813  -25.931 1.00 47.46  ? 110 THR H OG1 1 
ATOM   780  C CG2 . THR A 1 110 ? -6.948  -1.209  -23.646 1.00 41.60  ? 110 THR H CG2 1 
ATOM   781  N N   . VAL A 1 111 ? -7.313  1.974   -22.382 1.00 44.62  ? 111 VAL H N   1 
ATOM   782  C CA  . VAL A 1 111 ? -7.324  2.367   -20.978 1.00 48.06  ? 111 VAL H CA  1 
ATOM   783  C C   . VAL A 1 111 ? -7.931  1.218   -20.183 1.00 40.81  ? 111 VAL H C   1 
ATOM   784  O O   . VAL A 1 111 ? -9.139  0.969   -20.263 1.00 46.48  ? 111 VAL H O   1 
ATOM   785  C CB  . VAL A 1 111 ? -8.106  3.668   -20.762 1.00 52.30  ? 111 VAL H CB  1 
ATOM   786  C CG1 . VAL A 1 111 ? -8.041  4.085   -19.300 1.00 52.32  ? 111 VAL H CG1 1 
ATOM   787  C CG2 . VAL A 1 111 ? -7.583  4.766   -21.677 1.00 51.64  ? 111 VAL H CG2 1 
ATOM   788  N N   . SER A 1 112 ? -7.103  0.514   -19.413 1.00 37.68  ? 112 SER H N   1 
ATOM   789  C CA  . SER A 1 112 ? -7.577  -0.651  -18.679 1.00 39.69  ? 112 SER H CA  1 
ATOM   790  C C   . SER A 1 112 ? -6.702  -0.895  -17.458 1.00 43.08  ? 112 SER H C   1 
ATOM   791  O O   . SER A 1 112 ? -5.506  -0.590  -17.458 1.00 45.46  ? 112 SER H O   1 
ATOM   792  C CB  . SER A 1 112 ? -7.595  -1.902  -19.566 1.00 42.07  ? 112 SER H CB  1 
ATOM   793  O OG  . SER A 1 112 ? -7.810  -3.068  -18.790 1.00 39.12  ? 112 SER H OG  1 
ATOM   794  N N   . SER A 1 113 ? -7.320  -1.448  -16.416 1.00 45.23  ? 113 SER H N   1 
ATOM   795  C CA  . SER A 1 113 ? -6.625  -1.891  -15.215 1.00 41.07  ? 113 SER H CA  1 
ATOM   796  C C   . SER A 1 113 ? -6.115  -3.322  -15.321 1.00 42.95  ? 113 SER H C   1 
ATOM   797  O O   . SER A 1 113 ? -5.460  -3.801  -14.390 1.00 40.28  ? 113 SER H O   1 
ATOM   798  C CB  . SER A 1 113 ? -7.548  -1.774  -13.997 1.00 40.46  ? 113 SER H CB  1 
ATOM   799  O OG  . SER A 1 113 ? -8.052  -0.458  -13.856 1.00 51.25  ? 113 SER H OG  1 
ATOM   800  N N   . ALA A 1 114 ? -6.394  -4.009  -16.425 1.00 41.87  ? 114 ALA H N   1 
ATOM   801  C CA  . ALA A 1 114 ? -6.064  -5.419  -16.545 1.00 40.05  ? 114 ALA H CA  1 
ATOM   802  C C   . ALA A 1 114 ? -4.559  -5.626  -16.683 1.00 42.80  ? 114 ALA H C   1 
ATOM   803  O O   . ALA A 1 114 ? -3.810  -4.736  -17.094 1.00 45.50  ? 114 ALA H O   1 
ATOM   804  C CB  . ALA A 1 114 ? -6.784  -6.037  -17.745 1.00 39.50  ? 114 ALA H CB  1 
ATOM   805  N N   . SER A 1 115 ? -4.123  -6.831  -16.328 1.00 41.80  ? 115 SER H N   1 
ATOM   806  C CA  . SER A 1 115 ? -2.729  -7.227  -16.425 1.00 42.80  ? 115 SER H CA  1 
ATOM   807  C C   . SER A 1 115 ? -2.570  -8.266  -17.527 1.00 43.60  ? 115 SER H C   1 
ATOM   808  O O   . SER A 1 115 ? -3.534  -8.915  -17.943 1.00 44.93  ? 115 SER H O   1 
ATOM   809  C CB  . SER A 1 115 ? -2.222  -7.791  -15.091 1.00 47.16  ? 115 SER H CB  1 
ATOM   810  O OG  . SER A 1 115 ? -2.328  -6.830  -14.054 1.00 52.21  ? 115 SER H OG  1 
ATOM   811  N N   . THR A 1 116 ? -1.335  -8.403  -18.006 1.00 50.37  ? 116 THR H N   1 
ATOM   812  C CA  . THR A 1 116 ? -1.047  -9.324  -19.097 1.00 44.69  ? 116 THR H CA  1 
ATOM   813  C C   . THR A 1 116 ? -1.461  -10.744 -18.729 1.00 40.92  ? 116 THR H C   1 
ATOM   814  O O   . THR A 1 116 ? -1.142  -11.236 -17.642 1.00 45.12  ? 116 THR H O   1 
ATOM   815  C CB  . THR A 1 116 ? 0.439   -9.277  -19.448 1.00 43.08  ? 116 THR H CB  1 
ATOM   816  O OG1 . THR A 1 116 ? 0.821   -7.923  -19.723 1.00 46.14  ? 116 THR H OG1 1 
ATOM   817  C CG2 . THR A 1 116 ? 0.724   -10.131 -20.675 1.00 38.59  ? 116 THR H CG2 1 
ATOM   818  N N   . LYS A 1 117 ? -2.173  -11.402 -19.640 1.00 42.87  ? 117 LYS H N   1 
ATOM   819  C CA  . LYS A 1 117 ? -2.637  -12.763 -19.405 1.00 39.21  ? 117 LYS H CA  1 
ATOM   820  C C   . LYS A 1 117 ? -2.814  -13.475 -20.736 1.00 38.98  ? 117 LYS H C   1 
ATOM   821  O O   . LYS A 1 117 ? -3.457  -12.944 -21.646 1.00 36.54  ? 117 LYS H O   1 
ATOM   822  C CB  . LYS A 1 117 ? -3.956  -12.771 -18.624 1.00 35.26  ? 117 LYS H CB  1 
ATOM   823  C CG  . LYS A 1 117 ? -4.598  -14.143 -18.518 1.00 36.53  ? 117 LYS H CG  1 
ATOM   824  C CD  . LYS A 1 117 ? -5.786  -14.139 -17.575 1.00 42.62  ? 117 LYS H CD  1 
ATOM   825  C CE  . LYS A 1 117 ? -6.439  -15.509 -17.511 1.00 50.61  ? 117 LYS H CE  1 
ATOM   826  N NZ  . LYS A 1 117 ? -5.900  -16.435 -18.545 1.00 49.20  ? 117 LYS H NZ  1 
ATOM   827  N N   . GLY A 1 118 ? -2.241  -14.672 -20.842 1.00 41.81  ? 118 GLY H N   1 
ATOM   828  C CA  . GLY A 1 118 ? -2.399  -15.491 -22.018 1.00 38.79  ? 118 GLY H CA  1 
ATOM   829  C C   . GLY A 1 118 ? -3.786  -16.094 -22.086 1.00 36.52  ? 118 GLY H C   1 
ATOM   830  O O   . GLY A 1 118 ? -4.480  -16.228 -21.073 1.00 38.14  ? 118 GLY H O   1 
ATOM   831  N N   . PRO A 1 119 ? -4.218  -16.474 -23.284 1.00 38.19  ? 119 PRO H N   1 
ATOM   832  C CA  . PRO A 1 119 ? -5.579  -16.978 -23.460 1.00 36.34  ? 119 PRO H CA  1 
ATOM   833  C C   . PRO A 1 119 ? -5.691  -18.480 -23.240 1.00 37.35  ? 119 PRO H C   1 
ATOM   834  O O   . PRO A 1 119 ? -4.722  -19.235 -23.347 1.00 36.24  ? 119 PRO H O   1 
ATOM   835  C CB  . PRO A 1 119 ? -5.877  -16.631 -24.923 1.00 35.14  ? 119 PRO H CB  1 
ATOM   836  C CG  . PRO A 1 119 ? -4.552  -16.779 -25.587 1.00 37.74  ? 119 PRO H CG  1 
ATOM   837  C CD  . PRO A 1 119 ? -3.522  -16.315 -24.574 1.00 37.48  ? 119 PRO H CD  1 
ATOM   838  N N   . SER A 1 120 ? -6.912  -18.899 -22.920 1.00 32.06  ? 120 SER H N   1 
ATOM   839  C CA  . SER A 1 120 ? -7.287  -20.303 -22.981 1.00 33.92  ? 120 SER H CA  1 
ATOM   840  C C   . SER A 1 120 ? -7.932  -20.573 -24.334 1.00 36.71  ? 120 SER H C   1 
ATOM   841  O O   . SER A 1 120 ? -8.800  -19.813 -24.777 1.00 33.73  ? 120 SER H O   1 
ATOM   842  C CB  . SER A 1 120 ? -8.247  -20.665 -21.848 1.00 39.64  ? 120 SER H CB  1 
ATOM   843  O OG  . SER A 1 120 ? -7.649  -20.457 -20.581 1.00 45.26  ? 120 SER H OG  1 
ATOM   844  N N   . VAL A 1 121 ? -7.511  -21.650 -24.986 1.00 37.46  ? 121 VAL H N   1 
ATOM   845  C CA  . VAL A 1 121 ? -8.013  -22.010 -26.305 1.00 33.79  ? 121 VAL H CA  1 
ATOM   846  C C   . VAL A 1 121 ? -8.853  -23.269 -26.145 1.00 43.47  ? 121 VAL H C   1 
ATOM   847  O O   . VAL A 1 121 ? -8.321  -24.353 -25.873 1.00 46.75  ? 121 VAL H O   1 
ATOM   848  C CB  . VAL A 1 121 ? -6.876  -22.217 -27.314 1.00 44.93  ? 121 VAL H CB  1 
ATOM   849  C CG1 . VAL A 1 121 ? -7.442  -22.475 -28.701 1.00 43.01  ? 121 VAL H CG1 1 
ATOM   850  C CG2 . VAL A 1 121 ? -5.948  -21.010 -27.323 1.00 42.25  ? 121 VAL H CG2 1 
ATOM   851  N N   . PHE A 1 122 ? -10.167 -23.128 -26.318 1.00 41.97  ? 122 PHE H N   1 
ATOM   852  C CA  . PHE A 1 122 ? -11.093 -24.243 -26.213 1.00 39.32  ? 122 PHE H CA  1 
ATOM   853  C C   . PHE A 1 122 ? -11.617 -24.631 -27.592 1.00 43.47  ? 122 PHE H C   1 
ATOM   854  O O   . PHE A 1 122 ? -11.744 -23.780 -28.475 1.00 38.26  ? 122 PHE H O   1 
ATOM   855  C CB  . PHE A 1 122 ? -12.276 -23.899 -25.300 1.00 42.33  ? 122 PHE H CB  1 
ATOM   856  C CG  . PHE A 1 122 ? -11.871 -23.456 -23.925 1.00 44.07  ? 122 PHE H CG  1 
ATOM   857  C CD1 . PHE A 1 122 ? -11.197 -24.317 -23.075 1.00 43.23  ? 122 PHE H CD1 1 
ATOM   858  C CD2 . PHE A 1 122 ? -12.168 -22.179 -23.480 1.00 41.27  ? 122 PHE H CD2 1 
ATOM   859  C CE1 . PHE A 1 122 ? -10.824 -23.911 -21.809 1.00 43.76  ? 122 PHE H CE1 1 
ATOM   860  C CE2 . PHE A 1 122 ? -11.799 -21.767 -22.215 1.00 40.13  ? 122 PHE H CE2 1 
ATOM   861  C CZ  . PHE A 1 122 ? -11.127 -22.635 -21.377 1.00 44.94  ? 122 PHE H CZ  1 
ATOM   862  N N   . PRO A 1 123 ? -11.911 -25.907 -27.819 1.00 41.85  ? 123 PRO H N   1 
ATOM   863  C CA  . PRO A 1 123 ? -12.410 -26.322 -29.131 1.00 43.39  ? 123 PRO H CA  1 
ATOM   864  C C   . PRO A 1 123 ? -13.895 -26.041 -29.293 1.00 39.81  ? 123 PRO H C   1 
ATOM   865  O O   . PRO A 1 123 ? -14.677 -26.100 -28.342 1.00 43.14  ? 123 PRO H O   1 
ATOM   866  C CB  . PRO A 1 123 ? -12.135 -27.829 -29.144 1.00 43.74  ? 123 PRO H CB  1 
ATOM   867  C CG  . PRO A 1 123 ? -12.266 -28.221 -27.714 1.00 47.02  ? 123 PRO H CG  1 
ATOM   868  C CD  . PRO A 1 123 ? -11.754 -27.052 -26.904 1.00 48.34  ? 123 PRO H CD  1 
ATOM   869  N N   . LEU A 1 124 ? -14.275 -25.727 -30.528 1.00 39.32  ? 124 LEU H N   1 
ATOM   870  C CA  . LEU A 1 124 ? -15.665 -25.650 -30.959 1.00 39.43  ? 124 LEU H CA  1 
ATOM   871  C C   . LEU A 1 124 ? -15.818 -26.808 -31.939 1.00 37.19  ? 124 LEU H C   1 
ATOM   872  O O   . LEU A 1 124 ? -15.560 -26.663 -33.136 1.00 39.33  ? 124 LEU H O   1 
ATOM   873  C CB  . LEU A 1 124 ? -15.990 -24.307 -31.607 1.00 37.09  ? 124 LEU H CB  1 
ATOM   874  C CG  . LEU A 1 124 ? -15.799 -23.047 -30.764 1.00 34.85  ? 124 LEU H CG  1 
ATOM   875  C CD1 . LEU A 1 124 ? -15.834 -21.804 -31.640 1.00 31.72  ? 124 LEU H CD1 1 
ATOM   876  C CD2 . LEU A 1 124 ? -16.863 -22.973 -29.688 1.00 33.44  ? 124 LEU H CD2 1 
ATOM   877  N N   . ALA A 1 125 ? -16.207 -27.966 -31.408 1.00 40.98  ? 125 ALA H N   1 
ATOM   878  C CA  . ALA A 1 125 ? -16.144 -29.224 -32.135 1.00 49.15  ? 125 ALA H CA  1 
ATOM   879  C C   . ALA A 1 125 ? -17.335 -29.365 -33.080 1.00 47.93  ? 125 ALA H C   1 
ATOM   880  O O   . ALA A 1 125 ? -18.450 -28.957 -32.743 1.00 50.20  ? 125 ALA H O   1 
ATOM   881  C CB  . ALA A 1 125 ? -16.116 -30.401 -31.161 1.00 49.28  ? 125 ALA H CB  1 
ATOM   882  N N   . PRO A 1 126 ? -17.122 -29.933 -34.264 1.00 50.52  ? 126 PRO H N   1 
ATOM   883  C CA  . PRO A 1 126 ? -18.242 -30.195 -35.172 1.00 57.68  ? 126 PRO H CA  1 
ATOM   884  C C   . PRO A 1 126 ? -19.032 -31.415 -34.725 1.00 64.32  ? 126 PRO H C   1 
ATOM   885  O O   . PRO A 1 126 ? -18.470 -32.414 -34.268 1.00 63.69  ? 126 PRO H O   1 
ATOM   886  C CB  . PRO A 1 126 ? -17.551 -30.439 -36.518 1.00 54.63  ? 126 PRO H CB  1 
ATOM   887  C CG  . PRO A 1 126 ? -16.220 -31.004 -36.140 1.00 57.86  ? 126 PRO H CG  1 
ATOM   888  C CD  . PRO A 1 126 ? -15.829 -30.336 -34.845 1.00 53.78  ? 126 PRO H CD  1 
ATOM   889  N N   . SER A 1 127 ? -20.354 -31.325 -34.855 1.00 69.47  ? 127 SER H N   1 
ATOM   890  C CA  . SER A 1 127 ? -21.241 -32.434 -34.538 1.00 73.88  ? 127 SER H CA  1 
ATOM   891  C C   . SER A 1 127 ? -22.356 -32.476 -35.576 1.00 76.78  ? 127 SER H C   1 
ATOM   892  O O   . SER A 1 127 ? -22.363 -31.710 -36.545 1.00 77.22  ? 127 SER H O   1 
ATOM   893  C CB  . SER A 1 127 ? -21.800 -32.308 -33.116 1.00 75.54  ? 127 SER H CB  1 
ATOM   894  O OG  . SER A 1 127 ? -22.079 -30.956 -32.799 1.00 81.42  ? 127 SER H OG  1 
ATOM   895  N N   . SER A 1 128 ? -23.305 -33.383 -35.370 1.00 78.24  ? 128 SER H N   1 
ATOM   896  C CA  . SER A 1 128 ? -24.467 -33.485 -36.244 1.00 83.38  ? 128 SER H CA  1 
ATOM   897  C C   . SER A 1 128 ? -25.333 -32.230 -36.181 1.00 84.06  ? 128 SER H C   1 
ATOM   898  O O   . SER A 1 128 ? -25.833 -31.761 -37.203 1.00 81.37  ? 128 SER H O   1 
ATOM   899  C CB  . SER A 1 128 ? -25.304 -34.714 -35.880 1.00 82.30  ? 128 SER H CB  1 
ATOM   900  O OG  . SER A 1 128 ? -25.797 -34.628 -34.554 1.00 77.60  ? 128 SER H OG  1 
ATOM   901  N N   . GLY A 1 133 ? -26.304 -30.227 -43.649 1.00 74.09  ? 133 GLY H N   1 
ATOM   902  C CA  . GLY A 1 133 ? -26.123 -30.934 -44.903 1.00 72.48  ? 133 GLY H CA  1 
ATOM   903  C C   . GLY A 1 133 ? -24.718 -31.473 -45.086 1.00 71.94  ? 133 GLY H C   1 
ATOM   904  O O   . GLY A 1 133 ? -24.210 -32.206 -44.237 1.00 74.44  ? 133 GLY H O   1 
ATOM   905  N N   . GLY A 1 134 ? -24.087 -31.109 -46.199 1.00 73.61  ? 134 GLY H N   1 
ATOM   906  C CA  . GLY A 1 134 ? -22.730 -31.518 -46.483 1.00 70.40  ? 134 GLY H CA  1 
ATOM   907  C C   . GLY A 1 134 ? -21.654 -30.574 -46.004 1.00 67.48  ? 134 GLY H C   1 
ATOM   908  O O   . GLY A 1 134 ? -20.472 -30.811 -46.269 1.00 60.80  ? 134 GLY H O   1 
ATOM   909  N N   . THR A 1 135 ? -22.023 -29.507 -45.302 1.00 65.96  ? 135 THR H N   1 
ATOM   910  C CA  . THR A 1 135 ? -21.077 -28.517 -44.803 1.00 59.19  ? 135 THR H CA  1 
ATOM   911  C C   . THR A 1 135 ? -21.086 -28.566 -43.281 1.00 60.47  ? 135 THR H C   1 
ATOM   912  O O   . THR A 1 135 ? -22.147 -28.439 -42.660 1.00 60.27  ? 135 THR H O   1 
ATOM   913  C CB  . THR A 1 135 ? -21.434 -27.116 -45.300 1.00 63.44  ? 135 THR H CB  1 
ATOM   914  O OG1 . THR A 1 135 ? -21.387 -27.089 -46.732 1.00 61.50  ? 135 THR H OG1 1 
ATOM   915  C CG2 . THR A 1 135 ? -20.462 -26.085 -44.743 1.00 51.59  ? 135 THR H CG2 1 
ATOM   916  N N   . ALA A 1 136 ? -19.912 -28.751 -42.685 1.00 61.06  ? 136 ALA H N   1 
ATOM   917  C CA  . ALA A 1 136 ? -19.760 -28.723 -41.240 1.00 55.19  ? 136 ALA H CA  1 
ATOM   918  C C   . ALA A 1 136 ? -18.968 -27.489 -40.831 1.00 51.57  ? 136 ALA H C   1 
ATOM   919  O O   . ALA A 1 136 ? -18.185 -26.949 -41.615 1.00 53.59  ? 136 ALA H O   1 
ATOM   920  C CB  . ALA A 1 136 ? -19.060 -29.987 -40.731 1.00 58.88  ? 136 ALA H CB  1 
ATOM   921  N N   . ALA A 1 137 ? -19.187 -27.037 -39.601 1.00 44.91  ? 137 ALA H N   1 
ATOM   922  C CA  . ALA A 1 137 ? -18.471 -25.896 -39.055 1.00 43.54  ? 137 ALA H CA  1 
ATOM   923  C C   . ALA A 1 137 ? -17.742 -26.309 -37.786 1.00 44.45  ? 137 ALA H C   1 
ATOM   924  O O   . ALA A 1 137 ? -18.282 -27.056 -36.964 1.00 42.45  ? 137 ALA H O   1 
ATOM   925  C CB  . ALA A 1 137 ? -19.423 -24.733 -38.759 1.00 40.73  ? 137 ALA H CB  1 
ATOM   926  N N   . LEU A 1 138 ? -16.515 -25.820 -37.630 1.00 41.69  ? 138 LEU H N   1 
ATOM   927  C CA  . LEU A 1 138 ? -15.741 -26.063 -36.421 1.00 40.51  ? 138 LEU H CA  1 
ATOM   928  C C   . LEU A 1 138 ? -14.912 -24.822 -36.128 1.00 39.33  ? 138 LEU H C   1 
ATOM   929  O O   . LEU A 1 138 ? -14.916 -23.861 -36.899 1.00 40.40  ? 138 LEU H O   1 
ATOM   930  C CB  . LEU A 1 138 ? -14.869 -27.320 -36.559 1.00 44.57  ? 138 LEU H CB  1 
ATOM   931  C CG  . LEU A 1 138 ? -13.971 -27.473 -37.789 1.00 52.87  ? 138 LEU H CG  1 
ATOM   932  C CD1 . LEU A 1 138 ? -12.602 -26.849 -37.562 1.00 46.14  ? 138 LEU H CD1 1 
ATOM   933  C CD2 . LEU A 1 138 ? -13.844 -28.941 -38.178 1.00 53.19  ? 138 LEU H CD2 1 
ATOM   934  N N   . GLY A 1 139 ? -14.225 -24.819 -34.994 1.00 37.32  ? 139 GLY H N   1 
ATOM   935  C CA  . GLY A 1 139 ? -13.390 -23.674 -34.685 1.00 36.41  ? 139 GLY H CA  1 
ATOM   936  C C   . GLY A 1 139 ? -12.734 -23.732 -33.326 1.00 36.57  ? 139 GLY H C   1 
ATOM   937  O O   . GLY A 1 139 ? -12.643 -24.785 -32.694 1.00 36.56  ? 139 GLY H O   1 
ATOM   938  N N   . CYS A 1 140 ? -12.290 -22.558 -32.882 1.00 36.36  ? 140 CYS H N   1 
ATOM   939  C CA  . CYS A 1 140 ? -11.598 -22.394 -31.613 1.00 33.69  ? 140 CYS H CA  1 
ATOM   940  C C   . CYS A 1 140 ? -12.067 -21.118 -30.931 1.00 33.51  ? 140 CYS H C   1 
ATOM   941  O O   . CYS A 1 140 ? -12.223 -20.076 -31.576 1.00 36.01  ? 140 CYS H O   1 
ATOM   942  C CB  . CYS A 1 140 ? -10.074 -22.351 -31.806 1.00 40.95  ? 140 CYS H CB  1 
ATOM   943  S SG  . CYS A 1 140 ? -9.322  -23.961 -32.133 1.00 56.60  ? 140 CYS H SG  1 
ATOM   944  N N   . LEU A 1 141 ? -12.291 -21.212 -29.623 1.00 35.21  ? 141 LEU H N   1 
ATOM   945  C CA  . LEU A 1 141 ? -12.642 -20.072 -28.788 1.00 34.48  ? 141 LEU H CA  1 
ATOM   946  C C   . LEU A 1 141 ? -11.406 -19.656 -28.000 1.00 35.99  ? 141 LEU H C   1 
ATOM   947  O O   . LEU A 1 141 ? -10.887 -20.437 -27.193 1.00 37.79  ? 141 LEU H O   1 
ATOM   948  C CB  . LEU A 1 141 ? -13.797 -20.425 -27.849 1.00 31.80  ? 141 LEU H CB  1 
ATOM   949  C CG  . LEU A 1 141 ? -14.313 -19.343 -26.898 1.00 31.64  ? 141 LEU H CG  1 
ATOM   950  C CD1 . LEU A 1 141 ? -14.906 -18.187 -27.684 1.00 29.86  ? 141 LEU H CD1 1 
ATOM   951  C CD2 . LEU A 1 141 ? -15.340 -19.917 -25.933 1.00 39.00  ? 141 LEU H CD2 1 
ATOM   952  N N   . VAL A 1 142 ? -10.938 -18.435 -28.241 1.00 31.96  ? 142 VAL H N   1 
ATOM   953  C CA  . VAL A 1 142 ? -9.746  -17.887 -27.608 1.00 30.10  ? 142 VAL H CA  1 
ATOM   954  C C   . VAL A 1 142 ? -10.247 -16.906 -26.554 1.00 32.22  ? 142 VAL H C   1 
ATOM   955  O O   . VAL A 1 142 ? -10.685 -15.798 -26.877 1.00 26.43  ? 142 VAL H O   1 
ATOM   956  C CB  . VAL A 1 142 ? -8.828  -17.218 -28.635 1.00 36.31  ? 142 VAL H CB  1 
ATOM   957  C CG1 . VAL A 1 142 ? -7.525  -16.779 -27.997 1.00 35.77  ? 142 VAL H CG1 1 
ATOM   958  C CG2 . VAL A 1 142 ? -8.573  -18.159 -29.810 1.00 32.47  ? 142 VAL H CG2 1 
ATOM   959  N N   . LYS A 1 143 ? -10.193 -17.314 -25.288 1.00 29.94  ? 143 LYS H N   1 
ATOM   960  C CA  . LYS A 1 143 ? -10.921 -16.651 -24.217 1.00 35.34  ? 143 LYS H CA  1 
ATOM   961  C C   . LYS A 1 143 ? -9.977  -16.188 -23.112 1.00 34.30  ? 143 LYS H C   1 
ATOM   962  O O   . LYS A 1 143 ? -8.958  -16.830 -22.831 1.00 37.98  ? 143 LYS H O   1 
ATOM   963  C CB  . LYS A 1 143 ? -11.989 -17.605 -23.653 1.00 35.39  ? 143 LYS H CB  1 
ATOM   964  C CG  . LYS A 1 143 ? -13.058 -16.983 -22.771 1.00 32.84  ? 143 LYS H CG  1 
ATOM   965  C CD  . LYS A 1 143 ? -14.271 -17.906 -22.704 1.00 36.50  ? 143 LYS H CD  1 
ATOM   966  C CE  . LYS A 1 143 ? -15.088 -17.686 -21.442 1.00 38.28  ? 143 LYS H CE  1 
ATOM   967  N NZ  . LYS A 1 143 ? -14.960 -16.302 -20.913 1.00 36.93  ? 143 LYS H NZ  1 
ATOM   968  N N   . ASP A 1 144 ? -10.323 -15.047 -22.504 1.00 31.72  ? 144 ASP H N   1 
ATOM   969  C CA  . ASP A 1 144 ? -9.700  -14.568 -21.274 1.00 32.15  ? 144 ASP H CA  1 
ATOM   970  C C   . ASP A 1 144 ? -8.226  -14.235 -21.471 1.00 37.45  ? 144 ASP H C   1 
ATOM   971  O O   . ASP A 1 144 ? -7.359  -14.813 -20.809 1.00 32.86  ? 144 ASP H O   1 
ATOM   972  C CB  . ASP A 1 144 ? -9.881  -15.590 -20.150 1.00 33.93  ? 144 ASP H CB  1 
ATOM   973  C CG  . ASP A 1 144 ? -11.339 -15.806 -19.796 1.00 40.22  ? 144 ASP H CG  1 
ATOM   974  O OD1 . ASP A 1 144 ? -12.159 -14.904 -20.069 1.00 33.61  ? 144 ASP H OD1 1 
ATOM   975  O OD2 . ASP A 1 144 ? -11.667 -16.878 -19.247 1.00 45.94  ? 144 ASP H OD2 1 
ATOM   976  N N   . TYR A 1 145 ? -7.932  -13.301 -22.375 1.00 29.30  ? 145 TYR H N   1 
ATOM   977  C CA  . TYR A 1 145 ? -6.576  -12.817 -22.582 1.00 30.52  ? 145 TYR H CA  1 
ATOM   978  C C   . TYR A 1 145 ? -6.551  -11.298 -22.501 1.00 31.32  ? 145 TYR H C   1 
ATOM   979  O O   . TYR A 1 145 ? -7.584  -10.629 -22.595 1.00 31.29  ? 145 TYR H O   1 
ATOM   980  C CB  . TYR A 1 145 ? -5.994  -13.272 -23.932 1.00 33.01  ? 145 TYR H CB  1 
ATOM   981  C CG  . TYR A 1 145 ? -6.679  -12.701 -25.157 1.00 31.00  ? 145 TYR H CG  1 
ATOM   982  C CD1 . TYR A 1 145 ? -6.270  -11.491 -25.706 1.00 32.78  ? 145 TYR H CD1 1 
ATOM   983  C CD2 . TYR A 1 145 ? -7.717  -13.383 -25.778 1.00 30.64  ? 145 TYR H CD2 1 
ATOM   984  C CE1 . TYR A 1 145 ? -6.887  -10.969 -26.828 1.00 31.08  ? 145 TYR H CE1 1 
ATOM   985  C CE2 . TYR A 1 145 ? -8.338  -12.869 -26.902 1.00 33.33  ? 145 TYR H CE2 1 
ATOM   986  C CZ  . TYR A 1 145 ? -7.919  -11.663 -27.422 1.00 33.98  ? 145 TYR H CZ  1 
ATOM   987  O OH  . TYR A 1 145 ? -8.535  -11.148 -28.539 1.00 34.19  ? 145 TYR H OH  1 
ATOM   988  N N   . PHE A 1 146 ? -5.341  -10.760 -22.320 1.00 33.90  ? 146 PHE H N   1 
ATOM   989  C CA  . PHE A 1 146 ? -5.116  -9.323  -22.294 1.00 32.64  ? 146 PHE H CA  1 
ATOM   990  C C   . PHE A 1 146 ? -3.637  -9.074  -22.520 1.00 30.25  ? 146 PHE H C   1 
ATOM   991  O O   . PHE A 1 146 ? -2.810  -9.822  -21.981 1.00 36.89  ? 146 PHE H O   1 
ATOM   992  C CB  . PHE A 1 146 ? -5.558  -8.703  -20.963 1.00 34.03  ? 146 PHE H CB  1 
ATOM   993  C CG  . PHE A 1 146 ? -5.475  -7.200  -20.938 1.00 32.45  ? 146 PHE H CG  1 
ATOM   994  C CD1 . PHE A 1 146 ? -6.553  -6.429  -21.339 1.00 31.00  ? 146 PHE H CD1 1 
ATOM   995  C CD2 . PHE A 1 146 ? -4.317  -6.558  -20.523 1.00 34.17  ? 146 PHE H CD2 1 
ATOM   996  C CE1 . PHE A 1 146 ? -6.484  -5.048  -21.321 1.00 30.03  ? 146 PHE H CE1 1 
ATOM   997  C CE2 . PHE A 1 146 ? -4.242  -5.177  -20.504 1.00 35.69  ? 146 PHE H CE2 1 
ATOM   998  C CZ  . PHE A 1 146 ? -5.326  -4.421  -20.903 1.00 32.87  ? 146 PHE H CZ  1 
ATOM   999  N N   . PRO A 1 147 ? -3.262  -8.052  -23.294 1.00 31.14  ? 147 PRO H N   1 
ATOM   1000 C CA  . PRO A 1 147 ? -4.125  -7.158  -24.071 1.00 32.51  ? 147 PRO H CA  1 
ATOM   1001 C C   . PRO A 1 147 ? -4.291  -7.651  -25.501 1.00 33.27  ? 147 PRO H C   1 
ATOM   1002 O O   . PRO A 1 147 ? -3.858  -8.750  -25.843 1.00 31.85  ? 147 PRO H O   1 
ATOM   1003 C CB  . PRO A 1 147 ? -3.367  -5.830  -24.005 1.00 35.18  ? 147 PRO H CB  1 
ATOM   1004 C CG  . PRO A 1 147 ? -1.924  -6.264  -24.054 1.00 33.41  ? 147 PRO H CG  1 
ATOM   1005 C CD  . PRO A 1 147 ? -1.864  -7.583  -23.299 1.00 31.66  ? 147 PRO H CD  1 
ATOM   1006 N N   . GLU A 1 148 ? -4.925  -6.857  -26.357 1.00 36.11  ? 148 GLU H N   1 
ATOM   1007 C CA  . GLU A 1 148 ? -4.936  -7.164  -27.775 1.00 31.73  ? 148 GLU H CA  1 
ATOM   1008 C C   . GLU A 1 148 ? -3.520  -7.040  -28.340 1.00 35.61  ? 148 GLU H C   1 
ATOM   1009 O O   . GLU A 1 148 ? -2.693  -6.296  -27.805 1.00 33.22  ? 148 GLU H O   1 
ATOM   1010 C CB  . GLU A 1 148 ? -5.882  -6.219  -28.514 1.00 33.38  ? 148 GLU H CB  1 
ATOM   1011 C CG  . GLU A 1 148 ? -7.357  -6.513  -28.288 1.00 33.77  ? 148 GLU H CG  1 
ATOM   1012 C CD  . GLU A 1 148 ? -7.930  -7.468  -29.318 1.00 41.20  ? 148 GLU H CD  1 
ATOM   1013 O OE1 . GLU A 1 148 ? -7.422  -8.602  -29.419 1.00 40.71  ? 148 GLU H OE1 1 
ATOM   1014 O OE2 . GLU A 1 148 ? -8.890  -7.087  -30.019 1.00 46.35  ? 148 GLU H OE2 1 
ATOM   1015 N N   . PRO A 1 149 ? -3.210  -7.761  -29.425 1.00 32.73  ? 149 PRO H N   1 
ATOM   1016 C CA  . PRO A 1 149 ? -4.056  -8.714  -30.144 1.00 32.40  ? 149 PRO H CA  1 
ATOM   1017 C C   . PRO A 1 149 ? -3.585  -10.158 -30.021 1.00 34.08  ? 149 PRO H C   1 
ATOM   1018 O O   . PRO A 1 149 ? -2.532  -10.443 -29.456 1.00 36.35  ? 149 PRO H O   1 
ATOM   1019 C CB  . PRO A 1 149 ? -3.928  -8.219  -31.584 1.00 37.34  ? 149 PRO H CB  1 
ATOM   1020 C CG  . PRO A 1 149 ? -2.459  -7.838  -31.665 1.00 33.03  ? 149 PRO H CG  1 
ATOM   1021 C CD  . PRO A 1 149 ? -2.075  -7.346  -30.271 1.00 35.89  ? 149 PRO H CD  1 
ATOM   1022 N N   . VAL A 1 150 ? -4.378  -11.091 -30.541 1.00 32.08  ? 150 VAL H N   1 
ATOM   1023 C CA  . VAL A 1 150 ? -3.932  -12.451 -30.802 1.00 33.60  ? 150 VAL H CA  1 
ATOM   1024 C C   . VAL A 1 150 ? -4.027  -12.686 -32.302 1.00 32.77  ? 150 VAL H C   1 
ATOM   1025 O O   . VAL A 1 150 ? -4.757  -11.996 -33.019 1.00 33.92  ? 150 VAL H O   1 
ATOM   1026 C CB  . VAL A 1 150 ? -4.754  -13.507 -30.033 1.00 37.99  ? 150 VAL H CB  1 
ATOM   1027 C CG1 . VAL A 1 150 ? -4.761  -13.199 -28.545 1.00 35.60  ? 150 VAL H CG1 1 
ATOM   1028 C CG2 . VAL A 1 150 ? -6.172  -13.580 -30.582 1.00 30.57  ? 150 VAL H CG2 1 
ATOM   1029 N N   . THR A 1 151 ? -3.269  -13.668 -32.779 1.00 31.49  ? 151 THR H N   1 
ATOM   1030 C CA  . THR A 1 151 ? -3.370  -14.109 -34.162 1.00 34.40  ? 151 THR H CA  1 
ATOM   1031 C C   . THR A 1 151 ? -3.778  -15.573 -34.186 1.00 35.46  ? 151 THR H C   1 
ATOM   1032 O O   . THR A 1 151 ? -3.345  -16.361 -33.340 1.00 34.74  ? 151 THR H O   1 
ATOM   1033 C CB  . THR A 1 151 ? -2.052  -13.914 -34.921 1.00 31.62  ? 151 THR H CB  1 
ATOM   1034 O OG1 . THR A 1 151 ? -1.008  -14.656 -34.279 1.00 31.85  ? 151 THR H OG1 1 
ATOM   1035 C CG2 . THR A 1 151 ? -1.675  -12.440 -34.965 1.00 35.25  ? 151 THR H CG2 1 
ATOM   1036 N N   . VAL A 1 152 ? -4.617  -15.932 -35.154 1.00 37.81  ? 152 VAL H N   1 
ATOM   1037 C CA  . VAL A 1 152 ? -5.104  -17.296 -35.305 1.00 34.74  ? 152 VAL H CA  1 
ATOM   1038 C C   . VAL A 1 152 ? -4.881  -17.728 -36.746 1.00 38.77  ? 152 VAL H C   1 
ATOM   1039 O O   . VAL A 1 152 ? -5.269  -17.019 -37.681 1.00 36.56  ? 152 VAL H O   1 
ATOM   1040 C CB  . VAL A 1 152 ? -6.594  -17.429 -34.931 1.00 37.56  ? 152 VAL H CB  1 
ATOM   1041 C CG1 . VAL A 1 152 ? -7.014  -18.892 -34.951 1.00 35.72  ? 152 VAL H CG1 1 
ATOM   1042 C CG2 . VAL A 1 152 ? -6.866  -16.813 -33.566 1.00 34.06  ? 152 VAL H CG2 1 
ATOM   1043 N N   . SER A 1 153 ? -4.258  -18.886 -36.920 1.00 34.67  ? 153 SER H N   1 
ATOM   1044 C CA  . SER A 1 153 ? -4.149  -19.542 -38.213 1.00 39.64  ? 153 SER H CA  1 
ATOM   1045 C C   . SER A 1 153 ? -4.726  -20.947 -38.098 1.00 41.11  ? 153 SER H C   1 
ATOM   1046 O O   . SER A 1 153 ? -5.028  -21.431 -37.006 1.00 38.55  ? 153 SER H O   1 
ATOM   1047 C CB  . SER A 1 153 ? -2.693  -19.588 -38.696 1.00 43.64  ? 153 SER H CB  1 
ATOM   1048 O OG  . SER A 1 153 ? -1.900  -20.416 -37.865 1.00 45.47  ? 153 SER H OG  1 
ATOM   1049 N N   . TRP A 1 154 ? -4.886  -21.609 -39.241 1.00 38.58  ? 154 TRP H N   1 
ATOM   1050 C CA  . TRP A 1 154 ? -5.429  -22.961 -39.270 1.00 40.43  ? 154 TRP H CA  1 
ATOM   1051 C C   . TRP A 1 154 ? -4.500  -23.868 -40.060 1.00 41.44  ? 154 TRP H C   1 
ATOM   1052 O O   . TRP A 1 154 ? -4.131  -23.548 -41.195 1.00 42.06  ? 154 TRP H O   1 
ATOM   1053 C CB  . TRP A 1 154 ? -6.838  -22.974 -39.869 1.00 40.69  ? 154 TRP H CB  1 
ATOM   1054 C CG  . TRP A 1 154 ? -7.880  -22.501 -38.902 1.00 41.27  ? 154 TRP H CG  1 
ATOM   1055 C CD1 . TRP A 1 154 ? -8.351  -21.227 -38.760 1.00 37.57  ? 154 TRP H CD1 1 
ATOM   1056 C CD2 . TRP A 1 154 ? -8.568  -23.293 -37.927 1.00 37.15  ? 154 TRP H CD2 1 
ATOM   1057 N NE1 . TRP A 1 154 ? -9.295  -21.180 -37.763 1.00 35.60  ? 154 TRP H NE1 1 
ATOM   1058 C CE2 . TRP A 1 154 ? -9.447  -22.436 -37.237 1.00 34.70  ? 154 TRP H CE2 1 
ATOM   1059 C CE3 . TRP A 1 154 ? -8.529  -24.646 -37.575 1.00 42.06  ? 154 TRP H CE3 1 
ATOM   1060 C CZ2 . TRP A 1 154 ? -10.279 -22.887 -36.215 1.00 33.05  ? 154 TRP H CZ2 1 
ATOM   1061 C CZ3 . TRP A 1 154 ? -9.355  -25.091 -36.560 1.00 41.43  ? 154 TRP H CZ3 1 
ATOM   1062 C CH2 . TRP A 1 154 ? -10.216 -24.215 -35.892 1.00 37.38  ? 154 TRP H CH2 1 
ATOM   1063 N N   . ASN A 1 155 ? -4.145  -25.006 -39.461 1.00 38.97  ? 155 ASN H N   1 
ATOM   1064 C CA  . ASN A 1 155 ? -3.220  -25.974 -40.050 1.00 45.48  ? 155 ASN H CA  1 
ATOM   1065 C C   . ASN A 1 155 ? -1.930  -25.296 -40.510 1.00 45.92  ? 155 ASN H C   1 
ATOM   1066 O O   . ASN A 1 155 ? -1.424  -25.540 -41.607 1.00 49.45  ? 155 ASN H O   1 
ATOM   1067 C CB  . ASN A 1 155 ? -3.884  -26.739 -41.196 1.00 41.14  ? 155 ASN H CB  1 
ATOM   1068 C CG  . ASN A 1 155 ? -5.050  -27.588 -40.730 1.00 46.75  ? 155 ASN H CG  1 
ATOM   1069 O OD1 . ASN A 1 155 ? -5.272  -27.750 -39.531 1.00 49.09  ? 155 ASN H OD1 1 
ATOM   1070 N ND2 . ASN A 1 155 ? -5.799  -28.139 -41.678 1.00 42.43  ? 155 ASN H ND2 1 
ATOM   1071 N N   . SER A 1 156 ? -1.399  -24.432 -39.642 1.00 46.18  ? 156 SER H N   1 
ATOM   1072 C CA  . SER A 1 156 ? -0.146  -23.714 -39.885 1.00 46.98  ? 156 SER H CA  1 
ATOM   1073 C C   . SER A 1 156 ? -0.200  -22.891 -41.169 1.00 48.80  ? 156 SER H C   1 
ATOM   1074 O O   . SER A 1 156 ? 0.821   -22.681 -41.828 1.00 47.55  ? 156 SER H O   1 
ATOM   1075 C CB  . SER A 1 156 ? 1.048   -24.674 -39.915 1.00 50.81  ? 156 SER H CB  1 
ATOM   1076 O OG  . SER A 1 156 ? 1.180   -25.359 -38.682 1.00 43.95  ? 156 SER H OG  1 
ATOM   1077 N N   . GLY A 1 157 ? -1.390  -22.416 -41.534 1.00 46.78  ? 157 GLY H N   1 
ATOM   1078 C CA  . GLY A 1 157 ? -1.569  -21.603 -42.717 1.00 42.46  ? 157 GLY H CA  1 
ATOM   1079 C C   . GLY A 1 157 ? -2.069  -22.348 -43.936 1.00 46.80  ? 157 GLY H C   1 
ATOM   1080 O O   . GLY A 1 157 ? -2.422  -21.703 -44.932 1.00 44.80  ? 157 GLY H O   1 
ATOM   1081 N N   . ALA A 1 158 ? -2.108  -23.682 -43.894 1.00 44.99  ? 158 ALA H N   1 
ATOM   1082 C CA  . ALA A 1 158 ? -2.538  -24.451 -45.055 1.00 45.49  ? 158 ALA H CA  1 
ATOM   1083 C C   . ALA A 1 158 ? -4.039  -24.359 -45.297 1.00 46.93  ? 158 ALA H C   1 
ATOM   1084 O O   . ALA A 1 158 ? -4.492  -24.657 -46.407 1.00 49.26  ? 158 ALA H O   1 
ATOM   1085 C CB  . ALA A 1 158 ? -2.128  -25.915 -44.897 1.00 38.40  ? 158 ALA H CB  1 
ATOM   1086 N N   . LEU A 1 159 ? -4.816  -23.954 -44.295 1.00 40.56  ? 159 LEU H N   1 
ATOM   1087 C CA  . LEU A 1 159 ? -6.267  -23.834 -44.408 1.00 33.43  ? 159 LEU H CA  1 
ATOM   1088 C C   . LEU A 1 159 ? -6.652  -22.372 -44.225 1.00 41.22  ? 159 LEU H C   1 
ATOM   1089 O O   . LEU A 1 159 ? -6.513  -21.822 -43.127 1.00 43.53  ? 159 LEU H O   1 
ATOM   1090 C CB  . LEU A 1 159 ? -6.968  -24.720 -43.379 1.00 42.76  ? 159 LEU H CB  1 
ATOM   1091 C CG  . LEU A 1 159 ? -8.495  -24.664 -43.309 1.00 41.68  ? 159 LEU H CG  1 
ATOM   1092 C CD1 . LEU A 1 159 ? -9.120  -25.025 -44.648 1.00 38.14  ? 159 LEU H CD1 1 
ATOM   1093 C CD2 . LEU A 1 159 ? -9.010  -25.584 -42.212 1.00 38.92  ? 159 LEU H CD2 1 
ATOM   1094 N N   . THR A 1 160 ? -7.130  -21.742 -45.299 1.00 41.36  ? 160 THR H N   1 
ATOM   1095 C CA  . THR A 1 160 ? -7.547  -20.345 -45.241 1.00 41.42  ? 160 THR H CA  1 
ATOM   1096 C C   . THR A 1 160 ? -8.965  -20.173 -45.770 1.00 44.79  ? 160 THR H C   1 
ATOM   1097 O O   . THR A 1 160 ? -9.686  -19.265 -45.342 1.00 45.71  ? 160 THR H O   1 
ATOM   1098 C CB  . THR A 1 160 ? -6.583  -19.457 -46.033 1.00 44.74  ? 160 THR H CB  1 
ATOM   1099 O OG1 . THR A 1 160 ? -6.513  -19.912 -47.390 1.00 51.95  ? 160 THR H OG1 1 
ATOM   1100 C CG2 . THR A 1 160 ? -5.192  -19.487 -45.416 1.00 42.03  ? 160 THR H CG2 1 
ATOM   1101 N N   . SER A 1 161 ? -9.373  -21.033 -46.701 1.00 46.74  ? 161 SER H N   1 
ATOM   1102 C CA  . SER A 1 161 ? -10.693 -20.912 -47.305 1.00 44.63  ? 161 SER H CA  1 
ATOM   1103 C C   . SER A 1 161 ? -11.776 -21.269 -46.295 1.00 41.02  ? 161 SER H C   1 
ATOM   1104 O O   . SER A 1 161 ? -11.713 -22.315 -45.641 1.00 38.40  ? 161 SER H O   1 
ATOM   1105 C CB  . SER A 1 161 ? -10.800 -21.807 -48.539 1.00 45.39  ? 161 SER H CB  1 
ATOM   1106 O OG  . SER A 1 161 ? -10.150 -21.218 -49.652 1.00 48.25  ? 161 SER H OG  1 
ATOM   1107 N N   . GLY A 1 162 ? -12.773 -20.395 -46.174 1.00 39.28  ? 162 GLY H N   1 
ATOM   1108 C CA  . GLY A 1 162 ? -13.857 -20.596 -45.236 1.00 49.92  ? 162 GLY H CA  1 
ATOM   1109 C C   . GLY A 1 162 ? -13.566 -20.168 -43.817 1.00 40.54  ? 162 GLY H C   1 
ATOM   1110 O O   . GLY A 1 162 ? -14.396 -20.408 -42.933 1.00 41.43  ? 162 GLY H O   1 
ATOM   1111 N N   . VAL A 1 163 ? -12.420 -19.542 -43.568 1.00 40.13  ? 163 VAL H N   1 
ATOM   1112 C CA  . VAL A 1 163 ? -12.028 -19.127 -42.227 1.00 35.65  ? 163 VAL H CA  1 
ATOM   1113 C C   . VAL A 1 163 ? -12.616 -17.753 -41.932 1.00 35.76  ? 163 VAL H C   1 
ATOM   1114 O O   . VAL A 1 163 ? -12.489 -16.823 -42.738 1.00 33.26  ? 163 VAL H O   1 
ATOM   1115 C CB  . VAL A 1 163 ? -10.497 -19.112 -42.084 1.00 39.55  ? 163 VAL H CB  1 
ATOM   1116 C CG1 . VAL A 1 163 ? -10.090 -18.551 -40.730 1.00 36.07  ? 163 VAL H CG1 1 
ATOM   1117 C CG2 . VAL A 1 163 ? -9.935  -20.512 -42.278 1.00 38.34  ? 163 VAL H CG2 1 
ATOM   1118 N N   . HIS A 1 164 ? -13.265 -17.629 -40.776 1.00 36.25  ? 164 HIS H N   1 
ATOM   1119 C CA  . HIS A 1 164 ? -13.731 -16.349 -40.253 1.00 34.08  ? 164 HIS H CA  1 
ATOM   1120 C C   . HIS A 1 164 ? -13.204 -16.197 -38.833 1.00 38.50  ? 164 HIS H C   1 
ATOM   1121 O O   . HIS A 1 164 ? -13.621 -16.932 -37.932 1.00 37.73  ? 164 HIS H O   1 
ATOM   1122 C CB  . HIS A 1 164 ? -15.258 -16.250 -40.276 1.00 36.56  ? 164 HIS H CB  1 
ATOM   1123 C CG  . HIS A 1 164 ? -15.840 -16.159 -41.652 1.00 36.00  ? 164 HIS H CG  1 
ATOM   1124 N ND1 . HIS A 1 164 ? -16.579 -17.175 -42.219 1.00 37.09  ? 164 HIS H ND1 1 
ATOM   1125 C CD2 . HIS A 1 164 ? -15.797 -15.167 -42.573 1.00 33.77  ? 164 HIS H CD2 1 
ATOM   1126 C CE1 . HIS A 1 164 ? -16.964 -16.813 -43.430 1.00 39.82  ? 164 HIS H CE1 1 
ATOM   1127 N NE2 . HIS A 1 164 ? -16.502 -15.600 -43.670 1.00 35.94  ? 164 HIS H NE2 1 
ATOM   1128 N N   . THR A 1 165 ? -12.278 -15.262 -38.638 1.00 37.89  ? 165 THR H N   1 
ATOM   1129 C CA  . THR A 1 165 ? -11.776 -14.913 -37.313 1.00 33.04  ? 165 THR H CA  1 
ATOM   1130 C C   . THR A 1 165 ? -12.460 -13.620 -36.886 1.00 36.42  ? 165 THR H C   1 
ATOM   1131 O O   . THR A 1 165 ? -12.220 -12.559 -37.472 1.00 34.07  ? 165 THR H O   1 
ATOM   1132 C CB  . THR A 1 165 ? -10.256 -14.761 -37.317 1.00 31.74  ? 165 THR H CB  1 
ATOM   1133 O OG1 . THR A 1 165 ? -9.650  -16.020 -37.636 1.00 34.95  ? 165 THR H OG1 1 
ATOM   1134 C CG2 . THR A 1 165 ? -9.764  -14.309 -35.950 1.00 33.54  ? 165 THR H CG2 1 
ATOM   1135 N N   . PHE A 1 166 ? -13.308 -13.710 -35.869 1.00 31.47  ? 166 PHE H N   1 
ATOM   1136 C CA  . PHE A 1 166 ? -14.175 -12.601 -35.513 1.00 30.92  ? 166 PHE H CA  1 
ATOM   1137 C C   . PHE A 1 166 ? -13.428 -11.568 -34.672 1.00 29.81  ? 166 PHE H C   1 
ATOM   1138 O O   . PHE A 1 166 ? -12.450 -11.896 -33.995 1.00 29.83  ? 166 PHE H O   1 
ATOM   1139 C CB  . PHE A 1 166 ? -15.388 -13.103 -34.739 1.00 30.88  ? 166 PHE H CB  1 
ATOM   1140 C CG  . PHE A 1 166 ? -16.370 -13.856 -35.581 1.00 35.80  ? 166 PHE H CG  1 
ATOM   1141 C CD1 . PHE A 1 166 ? -16.227 -15.218 -35.784 1.00 32.97  ? 166 PHE H CD1 1 
ATOM   1142 C CD2 . PHE A 1 166 ? -17.430 -13.200 -36.183 1.00 32.21  ? 166 PHE H CD2 1 
ATOM   1143 C CE1 . PHE A 1 166 ? -17.129 -15.915 -36.563 1.00 38.20  ? 166 PHE H CE1 1 
ATOM   1144 C CE2 . PHE A 1 166 ? -18.335 -13.891 -36.966 1.00 29.37  ? 166 PHE H CE2 1 
ATOM   1145 C CZ  . PHE A 1 166 ? -18.184 -15.249 -37.155 1.00 31.04  ? 166 PHE H CZ  1 
ATOM   1146 N N   . PRO A 1 167 ? -13.861 -10.308 -34.717 1.00 32.47  ? 167 PRO H N   1 
ATOM   1147 C CA  . PRO A 1 167 ? -13.307 -9.311  -33.795 1.00 32.17  ? 167 PRO H CA  1 
ATOM   1148 C C   . PRO A 1 167 ? -13.533 -9.728  -32.350 1.00 35.56  ? 167 PRO H C   1 
ATOM   1149 O O   . PRO A 1 167 ? -14.571 -10.295 -32.002 1.00 30.99  ? 167 PRO H O   1 
ATOM   1150 C CB  . PRO A 1 167 ? -14.083 -8.035  -34.142 1.00 28.39  ? 167 PRO H CB  1 
ATOM   1151 C CG  . PRO A 1 167 ? -14.562 -8.247  -35.538 1.00 32.23  ? 167 PRO H CG  1 
ATOM   1152 C CD  . PRO A 1 167 ? -14.832 -9.717  -35.654 1.00 31.60  ? 167 PRO H CD  1 
ATOM   1153 N N   . ALA A 1 168 ? -12.544 -9.447  -31.508 1.00 36.74  ? 168 ALA H N   1 
ATOM   1154 C CA  . ALA A 1 168 ? -12.665 -9.770  -30.096 1.00 32.51  ? 168 ALA H CA  1 
ATOM   1155 C C   . ALA A 1 168 ? -13.710 -8.881  -29.432 1.00 32.06  ? 168 ALA H C   1 
ATOM   1156 O O   . ALA A 1 168 ? -13.935 -7.737  -29.836 1.00 32.97  ? 168 ALA H O   1 
ATOM   1157 C CB  . ALA A 1 168 ? -11.318 -9.611  -29.393 1.00 31.05  ? 168 ALA H CB  1 
ATOM   1158 N N   . VAL A 1 169 ? -14.356 -9.423  -28.405 1.00 34.35  ? 169 VAL H N   1 
ATOM   1159 C CA  . VAL A 1 169 ? -15.253 -8.652  -27.556 1.00 34.94  ? 169 VAL H CA  1 
ATOM   1160 C C   . VAL A 1 169 ? -14.592 -8.488  -26.198 1.00 36.76  ? 169 VAL H C   1 
ATOM   1161 O O   . VAL A 1 169 ? -13.831 -9.351  -25.743 1.00 31.86  ? 169 VAL H O   1 
ATOM   1162 C CB  . VAL A 1 169 ? -16.644 -9.309  -27.418 1.00 34.64  ? 169 VAL H CB  1 
ATOM   1163 C CG1 . VAL A 1 169 ? -17.300 -9.462  -28.782 1.00 30.85  ? 169 VAL H CG1 1 
ATOM   1164 C CG2 . VAL A 1 169 ? -16.539 -10.657 -26.716 1.00 33.22  ? 169 VAL H CG2 1 
ATOM   1165 N N   . LEU A 1 170 ? -14.870 -7.360  -25.554 1.00 32.09  ? 170 LEU H N   1 
ATOM   1166 C CA  . LEU A 1 170 ? -14.373 -7.102  -24.210 1.00 32.71  ? 170 LEU H CA  1 
ATOM   1167 C C   . LEU A 1 170 ? -15.409 -7.600  -23.209 1.00 36.32  ? 170 LEU H C   1 
ATOM   1168 O O   . LEU A 1 170 ? -16.541 -7.104  -23.180 1.00 35.58  ? 170 LEU H O   1 
ATOM   1169 C CB  . LEU A 1 170 ? -14.087 -5.615  -24.010 1.00 32.85  ? 170 LEU H CB  1 
ATOM   1170 C CG  . LEU A 1 170 ? -13.585 -5.197  -22.628 1.00 36.27  ? 170 LEU H CG  1 
ATOM   1171 C CD1 . LEU A 1 170 ? -12.304 -5.942  -22.277 1.00 34.03  ? 170 LEU H CD1 1 
ATOM   1172 C CD2 . LEU A 1 170 ? -13.363 -3.695  -22.573 1.00 33.26  ? 170 LEU H CD2 1 
ATOM   1173 N N   . GLN A 1 171 ? -15.023 -8.577  -22.396 1.00 33.08  ? 171 GLN H N   1 
ATOM   1174 C CA  . GLN A 1 171 ? -15.930 -9.143  -21.412 1.00 33.45  ? 171 GLN H CA  1 
ATOM   1175 C C   . GLN A 1 171 ? -15.959 -8.279  -20.153 1.00 36.33  ? 171 GLN H C   1 
ATOM   1176 O O   . GLN A 1 171 ? -15.120 -7.399  -19.947 1.00 31.31  ? 171 GLN H O   1 
ATOM   1177 C CB  . GLN A 1 171 ? -15.523 -10.576 -21.071 1.00 32.18  ? 171 GLN H CB  1 
ATOM   1178 C CG  . GLN A 1 171 ? -15.453 -11.504 -22.273 1.00 32.93  ? 171 GLN H CG  1 
ATOM   1179 C CD  . GLN A 1 171 ? -14.776 -12.822 -21.953 1.00 35.85  ? 171 GLN H CD  1 
ATOM   1180 O OE1 . GLN A 1 171 ? -15.432 -13.856 -21.821 1.00 38.45  ? 171 GLN H OE1 1 
ATOM   1181 N NE2 . GLN A 1 171 ? -13.455 -12.791 -21.821 1.00 33.35  ? 171 GLN H NE2 1 
ATOM   1182 N N   . SER A 1 172 ? -16.955 -8.540  -19.304 1.00 33.14  ? 172 SER H N   1 
ATOM   1183 C CA  . SER A 1 172 ? -17.076 -7.804  -18.050 1.00 32.19  ? 172 SER H CA  1 
ATOM   1184 C C   . SER A 1 172 ? -15.898 -8.057  -17.119 1.00 31.90  ? 172 SER H C   1 
ATOM   1185 O O   . SER A 1 172 ? -15.660 -7.260  -16.206 1.00 40.60  ? 172 SER H O   1 
ATOM   1186 C CB  . SER A 1 172 ? -18.386 -8.169  -17.348 1.00 30.48  ? 172 SER H CB  1 
ATOM   1187 O OG  . SER A 1 172 ? -18.445 -9.555  -17.060 1.00 34.16  ? 172 SER H OG  1 
ATOM   1188 N N   . SER A 1 173 ? -15.149 -9.138  -17.333 1.00 31.97  ? 173 SER H N   1 
ATOM   1189 C CA  . SER A 1 173 ? -13.946 -9.392  -16.550 1.00 31.83  ? 173 SER H CA  1 
ATOM   1190 C C   . SER A 1 173 ? -12.784 -8.495  -16.950 1.00 35.81  ? 173 SER H C   1 
ATOM   1191 O O   . SER A 1 173 ? -11.736 -8.541  -16.296 1.00 40.01  ? 173 SER H O   1 
ATOM   1192 C CB  . SER A 1 173 ? -13.535 -10.860 -16.685 1.00 33.58  ? 173 SER H CB  1 
ATOM   1193 O OG  . SER A 1 173 ? -13.233 -11.188 -18.032 1.00 38.01  ? 173 SER H OG  1 
ATOM   1194 N N   . GLY A 1 174 ? -12.941 -7.686  -17.996 1.00 33.94  ? 174 GLY H N   1 
ATOM   1195 C CA  . GLY A 1 174 ? -11.854 -6.899  -18.532 1.00 34.44  ? 174 GLY H CA  1 
ATOM   1196 C C   . GLY A 1 174 ? -10.936 -7.651  -19.467 1.00 34.76  ? 174 GLY H C   1 
ATOM   1197 O O   . GLY A 1 174 ? -9.984  -7.055  -19.986 1.00 34.95  ? 174 GLY H O   1 
ATOM   1198 N N   . LEU A 1 175 ? -11.193 -8.933  -19.701 1.00 36.41  ? 175 LEU H N   1 
ATOM   1199 C CA  . LEU A 1 175 ? -10.392 -9.757  -20.592 1.00 34.52  ? 175 LEU H CA  1 
ATOM   1200 C C   . LEU A 1 175 ? -11.112 -9.946  -21.921 1.00 35.25  ? 175 LEU H C   1 
ATOM   1201 O O   . LEU A 1 175 ? -12.344 -9.935  -21.991 1.00 32.95  ? 175 LEU H O   1 
ATOM   1202 C CB  . LEU A 1 175 ? -10.096 -11.119 -19.960 1.00 32.57  ? 175 LEU H CB  1 
ATOM   1203 C CG  . LEU A 1 175 ? -9.444  -11.096 -18.575 1.00 35.77  ? 175 LEU H CG  1 
ATOM   1204 C CD1 . LEU A 1 175 ? -9.262  -12.510 -18.048 1.00 33.66  ? 175 LEU H CD1 1 
ATOM   1205 C CD2 . LEU A 1 175 ? -8.113  -10.360 -18.618 1.00 36.74  ? 175 LEU H CD2 1 
ATOM   1206 N N   . TYR A 1 176 ? -10.328 -10.118 -22.977 1.00 33.44  ? 176 TYR H N   1 
ATOM   1207 C CA  . TYR A 1 176 ? -10.864 -10.242 -24.322 1.00 32.27  ? 176 TYR H CA  1 
ATOM   1208 C C   . TYR A 1 176 ? -11.200 -11.693 -24.649 1.00 29.61  ? 176 TYR H C   1 
ATOM   1209 O O   . TYR A 1 176 ? -10.635 -12.637 -24.091 1.00 29.42  ? 176 TYR H O   1 
ATOM   1210 C CB  . TYR A 1 176 ? -9.867  -9.700  -25.348 1.00 34.37  ? 176 TYR H CB  1 
ATOM   1211 C CG  . TYR A 1 176 ? -9.639  -8.209  -25.261 1.00 32.72  ? 176 TYR H CG  1 
ATOM   1212 C CD1 . TYR A 1 176 ? -10.486 -7.319  -25.905 1.00 32.19  ? 176 TYR H CD1 1 
ATOM   1213 C CD2 . TYR A 1 176 ? -8.578  -7.693  -24.530 1.00 31.56  ? 176 TYR H CD2 1 
ATOM   1214 C CE1 . TYR A 1 176 ? -10.281 -5.955  -25.828 1.00 36.62  ? 176 TYR H CE1 1 
ATOM   1215 C CE2 . TYR A 1 176 ? -8.364  -6.331  -24.447 1.00 33.21  ? 176 TYR H CE2 1 
ATOM   1216 C CZ  . TYR A 1 176 ? -9.219  -5.466  -25.099 1.00 34.07  ? 176 TYR H CZ  1 
ATOM   1217 O OH  . TYR A 1 176 ? -9.011  -4.108  -25.016 1.00 37.15  ? 176 TYR H OH  1 
ATOM   1218 N N   . SER A 1 177 ? -12.125 -11.857 -25.590 1.00 35.44  ? 177 SER H N   1 
ATOM   1219 C CA  . SER A 1 177 ? -12.510 -13.174 -26.069 1.00 33.53  ? 177 SER H CA  1 
ATOM   1220 C C   . SER A 1 177 ? -12.909 -13.058 -27.531 1.00 29.97  ? 177 SER H C   1 
ATOM   1221 O O   . SER A 1 177 ? -13.592 -12.108 -27.921 1.00 33.29  ? 177 SER H O   1 
ATOM   1222 C CB  . SER A 1 177 ? -13.663 -13.757 -25.244 1.00 29.78  ? 177 SER H CB  1 
ATOM   1223 O OG  . SER A 1 177 ? -14.082 -15.007 -25.763 1.00 32.20  ? 177 SER H OG  1 
ATOM   1224 N N   . LEU A 1 178 ? -12.472 -14.023 -28.334 1.00 29.42  ? 178 LEU H N   1 
ATOM   1225 C CA  . LEU A 1 178 ? -12.868 -14.089 -29.731 1.00 34.96  ? 178 LEU H CA  1 
ATOM   1226 C C   . LEU A 1 178 ? -13.030 -15.547 -30.127 1.00 31.83  ? 178 LEU H C   1 
ATOM   1227 O O   . LEU A 1 178 ? -12.701 -16.465 -29.371 1.00 35.99  ? 178 LEU H O   1 
ATOM   1228 C CB  . LEU A 1 178 ? -11.868 -13.364 -30.653 1.00 32.24  ? 178 LEU H CB  1 
ATOM   1229 C CG  . LEU A 1 178 ? -10.424 -13.826 -30.890 1.00 32.84  ? 178 LEU H CG  1 
ATOM   1230 C CD1 . LEU A 1 178 ? -10.324 -14.981 -31.887 1.00 31.18  ? 178 LEU H CD1 1 
ATOM   1231 C CD2 . LEU A 1 178 ? -9.601  -12.646 -31.372 1.00 34.79  ? 178 LEU H CD2 1 
ATOM   1232 N N   . SER A 1 179 ? -13.588 -15.751 -31.313 1.00 30.79  ? 179 SER H N   1 
ATOM   1233 C CA  . SER A 1 179 ? -13.720 -17.075 -31.891 1.00 34.83  ? 179 SER H CA  1 
ATOM   1234 C C   . SER A 1 179 ? -13.205 -17.044 -33.321 1.00 30.34  ? 179 SER H C   1 
ATOM   1235 O O   . SER A 1 179 ? -13.343 -16.040 -34.026 1.00 34.33  ? 179 SER H O   1 
ATOM   1236 C CB  . SER A 1 179 ? -15.175 -17.563 -31.867 1.00 34.21  ? 179 SER H CB  1 
ATOM   1237 O OG  . SER A 1 179 ? -16.009 -16.705 -32.627 1.00 33.30  ? 179 SER H OG  1 
ATOM   1238 N N   . SER A 1 180 ? -12.606 -18.154 -33.740 1.00 32.04  ? 180 SER H N   1 
ATOM   1239 C CA  . SER A 1 180 ? -12.184 -18.337 -35.122 1.00 33.91  ? 180 SER H CA  1 
ATOM   1240 C C   . SER A 1 180 ? -12.802 -19.630 -35.621 1.00 36.95  ? 180 SER H C   1 
ATOM   1241 O O   . SER A 1 180 ? -12.517 -20.702 -35.079 1.00 36.34  ? 180 SER H O   1 
ATOM   1242 C CB  . SER A 1 180 ? -10.659 -18.377 -35.244 1.00 34.11  ? 180 SER H CB  1 
ATOM   1243 O OG  . SER A 1 180 ? -10.260 -18.504 -36.598 1.00 33.52  ? 180 SER H OG  1 
ATOM   1244 N N   . VAL A 1 181 ? -13.637 -19.533 -36.652 1.00 35.21  ? 181 VAL H N   1 
ATOM   1245 C CA  . VAL A 1 181 ? -14.391 -20.671 -37.153 1.00 36.11  ? 181 VAL H CA  1 
ATOM   1246 C C   . VAL A 1 181 ? -14.002 -20.919 -38.604 1.00 38.62  ? 181 VAL H C   1 
ATOM   1247 O O   . VAL A 1 181 ? -13.388 -20.081 -39.263 1.00 42.37  ? 181 VAL H O   1 
ATOM   1248 C CB  . VAL A 1 181 ? -15.914 -20.467 -37.027 1.00 36.19  ? 181 VAL H CB  1 
ATOM   1249 C CG1 . VAL A 1 181 ? -16.285 -20.058 -35.608 1.00 34.51  ? 181 VAL H CG1 1 
ATOM   1250 C CG2 . VAL A 1 181 ? -16.397 -19.432 -38.035 1.00 37.44  ? 181 VAL H CG2 1 
ATOM   1251 N N   . VAL A 1 182 ? -14.374 -22.097 -39.094 1.00 32.83  ? 182 VAL H N   1 
ATOM   1252 C CA  . VAL A 1 182 ? -14.145 -22.470 -40.483 1.00 40.55  ? 182 VAL H CA  1 
ATOM   1253 C C   . VAL A 1 182 ? -15.147 -23.556 -40.850 1.00 41.96  ? 182 VAL H C   1 
ATOM   1254 O O   . VAL A 1 182 ? -15.461 -24.440 -40.042 1.00 38.14  ? 182 VAL H O   1 
ATOM   1255 C CB  . VAL A 1 182 ? -12.681 -22.919 -40.713 1.00 40.66  ? 182 VAL H CB  1 
ATOM   1256 C CG1 . VAL A 1 182 ? -12.316 -24.070 -39.793 1.00 40.84  ? 182 VAL H CG1 1 
ATOM   1257 C CG2 . VAL A 1 182 ? -12.448 -23.291 -42.172 1.00 41.79  ? 182 VAL H CG2 1 
ATOM   1258 N N   . THR A 1 183 ? -15.663 -23.464 -42.073 1.00 41.99  ? 183 THR H N   1 
ATOM   1259 C CA  . THR A 1 183 ? -16.566 -24.452 -42.642 1.00 45.16  ? 183 THR H CA  1 
ATOM   1260 C C   . THR A 1 183 ? -15.808 -25.345 -43.616 1.00 46.98  ? 183 THR H C   1 
ATOM   1261 O O   . THR A 1 183 ? -14.984 -24.870 -44.403 1.00 45.17  ? 183 THR H O   1 
ATOM   1262 C CB  . THR A 1 183 ? -17.739 -23.779 -43.357 1.00 45.77  ? 183 THR H CB  1 
ATOM   1263 O OG1 . THR A 1 183 ? -17.242 -22.824 -44.303 1.00 45.43  ? 183 THR H OG1 1 
ATOM   1264 C CG2 . THR A 1 183 ? -18.639 -23.072 -42.354 1.00 46.03  ? 183 THR H CG2 1 
ATOM   1265 N N   . VAL A 1 184 ? -16.097 -26.640 -43.555 1.00 51.09  ? 184 VAL H N   1 
ATOM   1266 C CA  . VAL A 1 184 ? -15.394 -27.652 -44.340 1.00 53.17  ? 184 VAL H CA  1 
ATOM   1267 C C   . VAL A 1 184 ? -16.404 -28.667 -44.868 1.00 56.95  ? 184 VAL H C   1 
ATOM   1268 O O   . VAL A 1 184 ? -17.564 -28.675 -44.425 1.00 55.03  ? 184 VAL H O   1 
ATOM   1269 C CB  . VAL A 1 184 ? -14.303 -28.344 -43.504 1.00 53.39  ? 184 VAL H CB  1 
ATOM   1270 C CG1 . VAL A 1 184 ? -13.197 -27.365 -43.136 1.00 50.24  ? 184 VAL H CG1 1 
ATOM   1271 C CG2 . VAL A 1 184 ? -14.910 -28.960 -42.251 1.00 53.66  ? 184 VAL H CG2 1 
ATOM   1272 N N   . PRO A 1 185 ? -16.030 -29.510 -45.832 1.00 55.72  ? 185 PRO H N   1 
ATOM   1273 C CA  . PRO A 1 185 ? -16.905 -30.629 -46.204 1.00 58.04  ? 185 PRO H CA  1 
ATOM   1274 C C   . PRO A 1 185 ? -17.037 -31.618 -45.057 1.00 58.32  ? 185 PRO H C   1 
ATOM   1275 O O   . PRO A 1 185 ? -16.076 -31.887 -44.332 1.00 61.91  ? 185 PRO H O   1 
ATOM   1276 C CB  . PRO A 1 185 ? -16.193 -31.256 -47.408 1.00 59.94  ? 185 PRO H CB  1 
ATOM   1277 C CG  . PRO A 1 185 ? -15.347 -30.156 -47.960 1.00 58.77  ? 185 PRO H CG  1 
ATOM   1278 C CD  . PRO A 1 185 ? -14.904 -29.359 -46.770 1.00 58.41  ? 185 PRO H CD  1 
ATOM   1279 N N   . SER A 1 186 ? -18.249 -32.153 -44.890 1.00 62.54  ? 186 SER H N   1 
ATOM   1280 C CA  . SER A 1 186 ? -18.488 -33.104 -43.808 1.00 60.84  ? 186 SER H CA  1 
ATOM   1281 C C   . SER A 1 186 ? -17.666 -34.374 -43.993 1.00 63.99  ? 186 SER H C   1 
ATOM   1282 O O   . SER A 1 186 ? -17.116 -34.914 -43.024 1.00 67.84  ? 186 SER H O   1 
ATOM   1283 C CB  . SER A 1 186 ? -19.978 -33.439 -43.727 1.00 66.45  ? 186 SER H CB  1 
ATOM   1284 O OG  . SER A 1 186 ? -20.761 -32.266 -43.588 1.00 70.20  ? 186 SER H OG  1 
ATOM   1285 N N   . SER A 1 187 ? -17.529 -34.838 -45.238 1.00 68.00  ? 187 SER H N   1 
ATOM   1286 C CA  . SER A 1 187 ? -16.791 -36.066 -45.511 1.00 75.45  ? 187 SER H CA  1 
ATOM   1287 C C   . SER A 1 187 ? -15.320 -35.967 -45.133 1.00 75.75  ? 187 SER H C   1 
ATOM   1288 O O   . SER A 1 187 ? -14.649 -37.002 -45.050 1.00 82.65  ? 187 SER H O   1 
ATOM   1289 C CB  . SER A 1 187 ? -16.915 -36.437 -46.991 1.00 75.89  ? 187 SER H CB  1 
ATOM   1290 O OG  . SER A 1 187 ? -16.324 -35.447 -47.817 1.00 72.92  ? 187 SER H OG  1 
ATOM   1291 N N   . SER A 1 188 ? -14.808 -34.763 -44.897 1.00 66.42  ? 188 SER H N   1 
ATOM   1292 C CA  . SER A 1 188 ? -13.418 -34.577 -44.512 1.00 70.09  ? 188 SER H CA  1 
ATOM   1293 C C   . SER A 1 188 ? -13.209 -34.639 -43.005 1.00 71.90  ? 188 SER H C   1 
ATOM   1294 O O   . SER A 1 188 ? -12.062 -34.563 -42.553 1.00 71.83  ? 188 SER H O   1 
ATOM   1295 C CB  . SER A 1 188 ? -12.897 -33.238 -45.045 1.00 65.34  ? 188 SER H CB  1 
ATOM   1296 O OG  . SER A 1 188 ? -13.283 -32.170 -44.197 1.00 66.02  ? 188 SER H OG  1 
ATOM   1297 N N   . LEU A 1 189 ? -14.280 -34.774 -42.217 1.00 68.39  ? 189 LEU H N   1 
ATOM   1298 C CA  . LEU A 1 189 ? -14.118 -34.766 -40.768 1.00 70.58  ? 189 LEU H CA  1 
ATOM   1299 C C   . LEU A 1 189 ? -13.428 -36.024 -40.257 1.00 75.79  ? 189 LEU H C   1 
ATOM   1300 O O   . LEU A 1 189 ? -12.874 -36.005 -39.152 1.00 74.00  ? 189 LEU H O   1 
ATOM   1301 C CB  . LEU A 1 189 ? -15.471 -34.582 -40.082 1.00 67.63  ? 189 LEU H CB  1 
ATOM   1302 C CG  . LEU A 1 189 ? -16.111 -33.208 -40.299 1.00 63.70  ? 189 LEU H CG  1 
ATOM   1303 C CD1 . LEU A 1 189 ? -17.237 -32.971 -39.306 1.00 62.74  ? 189 LEU H CD1 1 
ATOM   1304 C CD2 . LEU A 1 189 ? -15.070 -32.100 -40.215 1.00 68.92  ? 189 LEU H CD2 1 
ATOM   1305 N N   . GLY A 1 190 ? -13.444 -37.106 -41.030 1.00 72.80  ? 190 GLY H N   1 
ATOM   1306 C CA  . GLY A 1 190 ? -12.818 -38.343 -40.610 1.00 72.71  ? 190 GLY H CA  1 
ATOM   1307 C C   . GLY A 1 190 ? -11.434 -38.545 -41.192 1.00 77.82  ? 190 GLY H C   1 
ATOM   1308 O O   . GLY A 1 190 ? -10.701 -39.442 -40.764 1.00 80.15  ? 190 GLY H O   1 
ATOM   1309 N N   . THR A 1 191 ? -11.063 -37.720 -42.171 1.00 76.89  ? 191 THR H N   1 
ATOM   1310 C CA  . THR A 1 191 ? -9.797  -37.878 -42.873 1.00 77.43  ? 191 THR H CA  1 
ATOM   1311 C C   . THR A 1 191 ? -8.828  -36.723 -42.678 1.00 77.27  ? 191 THR H C   1 
ATOM   1312 O O   . THR A 1 191 ? -7.618  -36.934 -42.777 1.00 72.69  ? 191 THR H O   1 
ATOM   1313 C CB  . THR A 1 191 ? -10.038 -38.052 -44.382 1.00 80.30  ? 191 THR H CB  1 
ATOM   1314 O OG1 . THR A 1 191 ? -10.465 -36.805 -44.945 1.00 75.25  ? 191 THR H OG1 1 
ATOM   1315 C CG2 . THR A 1 191 ? -11.105 -39.106 -44.635 1.00 80.35  ? 191 THR H CG2 1 
ATOM   1316 N N   . GLN A 1 192 ? -9.316  -35.517 -42.406 1.00 70.74  ? 192 GLN H N   1 
ATOM   1317 C CA  . GLN A 1 192 ? -8.475  -34.333 -42.290 1.00 67.90  ? 192 GLN H CA  1 
ATOM   1318 C C   . GLN A 1 192 ? -8.405  -33.884 -40.837 1.00 61.16  ? 192 GLN H C   1 
ATOM   1319 O O   . GLN A 1 192 ? -9.439  -33.736 -40.177 1.00 60.33  ? 192 GLN H O   1 
ATOM   1320 C CB  . GLN A 1 192 ? -9.006  -33.197 -43.167 1.00 61.59  ? 192 GLN H CB  1 
ATOM   1321 C CG  . GLN A 1 192 ? -8.259  -31.881 -43.007 1.00 58.59  ? 192 GLN H CG  1 
ATOM   1322 C CD  . GLN A 1 192 ? -6.841  -31.942 -43.542 1.00 58.85  ? 192 GLN H CD  1 
ATOM   1323 O OE1 . GLN A 1 192 ? -5.887  -31.597 -42.844 1.00 60.09  ? 192 GLN H OE1 1 
ATOM   1324 N NE2 . GLN A 1 192 ? -6.697  -32.377 -44.789 1.00 65.02  ? 192 GLN H NE2 1 
ATOM   1325 N N   . THR A 1 193 ? -7.187  -33.669 -40.346 1.00 56.63  ? 193 THR H N   1 
ATOM   1326 C CA  . THR A 1 193 ? -6.988  -33.128 -39.009 1.00 58.33  ? 193 THR H CA  1 
ATOM   1327 C C   . THR A 1 193 ? -7.066  -31.607 -39.046 1.00 56.22  ? 193 THR H C   1 
ATOM   1328 O O   . THR A 1 193 ? -6.593  -30.970 -39.992 1.00 54.45  ? 193 THR H O   1 
ATOM   1329 C CB  . THR A 1 193 ? -5.640  -33.573 -38.441 1.00 61.45  ? 193 THR H CB  1 
ATOM   1330 O OG1 . THR A 1 193 ? -4.614  -33.371 -39.421 1.00 58.35  ? 193 THR H OG1 1 
ATOM   1331 C CG2 . THR A 1 193 ? -5.683  -35.043 -38.050 1.00 60.56  ? 193 THR H CG2 1 
ATOM   1332 N N   . TYR A 1 194 ? -7.668  -31.025 -38.011 1.00 50.71  ? 194 TYR H N   1 
ATOM   1333 C CA  . TYR A 1 194 ? -7.867  -29.583 -37.924 1.00 49.72  ? 194 TYR H CA  1 
ATOM   1334 C C   . TYR A 1 194 ? -7.243  -29.061 -36.639 1.00 48.72  ? 194 TYR H C   1 
ATOM   1335 O O   . TYR A 1 194 ? -7.647  -29.458 -35.541 1.00 50.85  ? 194 TYR H O   1 
ATOM   1336 C CB  . TYR A 1 194 ? -9.355  -29.234 -37.982 1.00 43.59  ? 194 TYR H CB  1 
ATOM   1337 C CG  . TYR A 1 194 ? -9.989  -29.547 -39.317 1.00 55.71  ? 194 TYR H CG  1 
ATOM   1338 C CD1 . TYR A 1 194 ? -9.772  -28.729 -40.417 1.00 50.90  ? 194 TYR H CD1 1 
ATOM   1339 C CD2 . TYR A 1 194 ? -10.799 -30.663 -39.479 1.00 54.27  ? 194 TYR H CD2 1 
ATOM   1340 C CE1 . TYR A 1 194 ? -10.344 -29.011 -41.640 1.00 48.42  ? 194 TYR H CE1 1 
ATOM   1341 C CE2 . TYR A 1 194 ? -11.376 -30.954 -40.700 1.00 54.22  ? 194 TYR H CE2 1 
ATOM   1342 C CZ  . TYR A 1 194 ? -11.145 -30.124 -41.777 1.00 54.15  ? 194 TYR H CZ  1 
ATOM   1343 O OH  . TYR A 1 194 ? -11.717 -30.407 -42.996 1.00 58.97  ? 194 TYR H OH  1 
ATOM   1344 N N   . ILE A 1 195 ? -6.262  -28.172 -36.780 1.00 48.00  ? 195 ILE H N   1 
ATOM   1345 C CA  . ILE A 1 195 ? -5.545  -27.585 -35.656 1.00 45.94  ? 195 ILE H CA  1 
ATOM   1346 C C   . ILE A 1 195 ? -5.536  -26.073 -35.830 1.00 44.19  ? 195 ILE H C   1 
ATOM   1347 O O   . ILE A 1 195 ? -5.163  -25.569 -36.896 1.00 41.01  ? 195 ILE H O   1 
ATOM   1348 C CB  . ILE A 1 195 ? -4.104  -28.122 -35.551 1.00 44.51  ? 195 ILE H CB  1 
ATOM   1349 C CG1 . ILE A 1 195 ? -4.102  -29.644 -35.406 1.00 48.73  ? 195 ILE H CG1 1 
ATOM   1350 C CG2 . ILE A 1 195 ? -3.372  -27.473 -34.386 1.00 42.77  ? 195 ILE H CG2 1 
ATOM   1351 C CD1 . ILE A 1 195 ? -2.724  -30.260 -35.493 1.00 43.58  ? 195 ILE H CD1 1 
ATOM   1352 N N   . CYS A 1 196 ? -5.947  -25.355 -34.790 1.00 40.88  ? 196 CYS H N   1 
ATOM   1353 C CA  . CYS A 1 196 ? -5.883  -23.900 -34.769 1.00 41.19  ? 196 CYS H CA  1 
ATOM   1354 C C   . CYS A 1 196 ? -4.631  -23.464 -34.018 1.00 40.87  ? 196 CYS H C   1 
ATOM   1355 O O   . CYS A 1 196 ? -4.335  -23.980 -32.934 1.00 43.14  ? 196 CYS H O   1 
ATOM   1356 C CB  . CYS A 1 196 ? -7.142  -23.300 -34.134 1.00 42.28  ? 196 CYS H CB  1 
ATOM   1357 S SG  . CYS A 1 196 ? -7.339  -23.580 -32.358 1.00 46.32  ? 196 CYS H SG  1 
ATOM   1358 N N   . ASN A 1 197 ? -3.895  -22.527 -34.606 1.00 39.02  ? 197 ASN H N   1 
ATOM   1359 C CA  . ASN A 1 197 ? -2.642  -22.022 -34.060 1.00 43.43  ? 197 ASN H CA  1 
ATOM   1360 C C   . ASN A 1 197 ? -2.884  -20.605 -33.553 1.00 38.74  ? 197 ASN H C   1 
ATOM   1361 O O   . ASN A 1 197 ? -3.094  -19.683 -34.351 1.00 38.88  ? 197 ASN H O   1 
ATOM   1362 C CB  . ASN A 1 197 ? -1.539  -22.056 -35.115 1.00 34.94  ? 197 ASN H CB  1 
ATOM   1363 C CG  . ASN A 1 197 ? -1.572  -23.323 -35.947 1.00 40.81  ? 197 ASN H CG  1 
ATOM   1364 O OD1 . ASN A 1 197 ? -1.855  -23.284 -37.144 1.00 41.87  ? 197 ASN H OD1 1 
ATOM   1365 N ND2 . ASN A 1 197 ? -1.286  -24.456 -35.315 1.00 40.30  ? 197 ASN H ND2 1 
ATOM   1366 N N   . VAL A 1 198 ? -2.875  -20.449 -32.231 1.00 38.28  ? 198 VAL H N   1 
ATOM   1367 C CA  . VAL A 1 198 ? -3.139  -19.182 -31.560 1.00 41.15  ? 198 VAL H CA  1 
ATOM   1368 C C   . VAL A 1 198 ? -1.823  -18.637 -31.026 1.00 41.88  ? 198 VAL H C   1 
ATOM   1369 O O   . VAL A 1 198 ? -1.049  -19.370 -30.396 1.00 39.35  ? 198 VAL H O   1 
ATOM   1370 C CB  . VAL A 1 198 ? -4.162  -19.354 -30.424 1.00 39.13  ? 198 VAL H CB  1 
ATOM   1371 C CG1 . VAL A 1 198 ? -4.372  -18.039 -29.685 1.00 33.03  ? 198 VAL H CG1 1 
ATOM   1372 C CG2 . VAL A 1 198 ? -5.477  -19.887 -30.971 1.00 41.83  ? 198 VAL H CG2 1 
ATOM   1373 N N   . ASN A 1 199 ? -1.577  -17.352 -31.272 1.00 37.02  ? 199 ASN H N   1 
ATOM   1374 C CA  . ASN A 1 199 ? -0.368  -16.677 -30.822 1.00 37.76  ? 199 ASN H CA  1 
ATOM   1375 C C   . ASN A 1 199 ? -0.751  -15.401 -30.090 1.00 36.67  ? 199 ASN H C   1 
ATOM   1376 O O   . ASN A 1 199 ? -1.497  -14.574 -30.627 1.00 31.83  ? 199 ASN H O   1 
ATOM   1377 C CB  . ASN A 1 199 ? 0.555   -16.353 -32.005 1.00 38.28  ? 199 ASN H CB  1 
ATOM   1378 C CG  . ASN A 1 199 ? 1.987   -16.081 -31.575 1.00 47.95  ? 199 ASN H CG  1 
ATOM   1379 O OD1 . ASN A 1 199 ? 2.244   -15.668 -30.444 1.00 54.12  ? 199 ASN H OD1 1 
ATOM   1380 N ND2 . ASN A 1 199 ? 2.929   -16.307 -32.485 1.00 53.81  ? 199 ASN H ND2 1 
ATOM   1381 N N   . HIS A 1 200 ? -0.240  -15.245 -28.868 1.00 38.89  ? 200 HIS H N   1 
ATOM   1382 C CA  . HIS A 1 200 ? -0.427  -14.038 -28.066 1.00 41.50  ? 200 HIS H CA  1 
ATOM   1383 C C   . HIS A 1 200 ? 0.960   -13.603 -27.601 1.00 42.52  ? 200 HIS H C   1 
ATOM   1384 O O   . HIS A 1 200 ? 1.509   -14.167 -26.647 1.00 42.47  ? 200 HIS H O   1 
ATOM   1385 C CB  . HIS A 1 200 ? -1.369  -14.279 -26.890 1.00 36.53  ? 200 HIS H CB  1 
ATOM   1386 C CG  . HIS A 1 200 ? -1.673  -13.045 -26.097 1.00 37.91  ? 200 HIS H CG  1 
ATOM   1387 N ND1 . HIS A 1 200 ? -1.280  -12.887 -24.785 1.00 35.17  ? 200 HIS H ND1 1 
ATOM   1388 C CD2 . HIS A 1 200 ? -2.326  -11.907 -26.433 1.00 33.56  ? 200 HIS H CD2 1 
ATOM   1389 C CE1 . HIS A 1 200 ? -1.682  -11.707 -24.346 1.00 37.95  ? 200 HIS H CE1 1 
ATOM   1390 N NE2 . HIS A 1 200 ? -2.319  -11.093 -25.326 1.00 36.11  ? 200 HIS H NE2 1 
ATOM   1391 N N   . LYS A 1 201 ? 1.534   -12.618 -28.302 1.00 41.63  ? 201 LYS H N   1 
ATOM   1392 C CA  . LYS A 1 201 ? 2.898   -12.192 -27.984 1.00 45.01  ? 201 LYS H CA  1 
ATOM   1393 C C   . LYS A 1 201 ? 3.034   -11.534 -26.619 1.00 47.76  ? 201 LYS H C   1 
ATOM   1394 O O   . LYS A 1 201 ? 4.002   -11.853 -25.906 1.00 47.93  ? 201 LYS H O   1 
ATOM   1395 C CB  . LYS A 1 201 ? 3.434   -11.262 -29.076 1.00 45.87  ? 201 LYS H CB  1 
ATOM   1396 C CG  . LYS A 1 201 ? 4.046   -11.914 -30.287 1.00 46.64  ? 201 LYS H CG  1 
ATOM   1397 C CD  . LYS A 1 201 ? 4.533   -10.782 -31.176 1.00 53.58  ? 201 LYS H CD  1 
ATOM   1398 C CE  . LYS A 1 201 ? 4.937   -11.218 -32.560 1.00 55.46  ? 201 LYS H CE  1 
ATOM   1399 N NZ  . LYS A 1 201 ? 5.406   -10.018 -33.312 1.00 54.90  ? 201 LYS H NZ  1 
ATOM   1400 N N   . PRO A 1 202 ? 2.167   -10.599 -26.204 1.00 43.71  ? 202 PRO H N   1 
ATOM   1401 C CA  . PRO A 1 202 ? 2.381   -9.927  -24.908 1.00 38.33  ? 202 PRO H CA  1 
ATOM   1402 C C   . PRO A 1 202 ? 2.570   -10.869 -23.732 1.00 43.57  ? 202 PRO H C   1 
ATOM   1403 O O   . PRO A 1 202 ? 3.254   -10.511 -22.763 1.00 43.01  ? 202 PRO H O   1 
ATOM   1404 C CB  . PRO A 1 202 ? 1.113   -9.077  -24.751 1.00 37.29  ? 202 PRO H CB  1 
ATOM   1405 C CG  . PRO A 1 202 ? 0.725   -8.762  -26.146 1.00 34.98  ? 202 PRO H CG  1 
ATOM   1406 C CD  . PRO A 1 202 ? 1.025   -10.007 -26.925 1.00 40.09  ? 202 PRO H CD  1 
ATOM   1407 N N   . SER A 1 203 ? 1.988   -12.061 -23.782 1.00 43.64  ? 203 SER H N   1 
ATOM   1408 C CA  . SER A 1 203 ? 2.206   -13.074 -22.762 1.00 45.37  ? 203 SER H CA  1 
ATOM   1409 C C   . SER A 1 203 ? 3.149   -14.171 -23.234 1.00 47.98  ? 203 SER H C   1 
ATOM   1410 O O   . SER A 1 203 ? 3.450   -15.086 -22.461 1.00 50.34  ? 203 SER H O   1 
ATOM   1411 C CB  . SER A 1 203 ? 0.869   -13.688 -22.336 1.00 44.16  ? 203 SER H CB  1 
ATOM   1412 O OG  . SER A 1 203 ? 0.270   -14.386 -23.413 1.00 46.42  ? 203 SER H OG  1 
ATOM   1413 N N   . ASN A 1 204 ? 3.628   -14.084 -24.475 1.00 52.05  ? 204 ASN H N   1 
ATOM   1414 C CA  . ASN A 1 204 ? 4.462   -15.115 -25.090 1.00 50.48  ? 204 ASN H CA  1 
ATOM   1415 C C   . ASN A 1 204 ? 3.825   -16.496 -24.960 1.00 50.79  ? 204 ASN H C   1 
ATOM   1416 O O   . ASN A 1 204 ? 4.453   -17.461 -24.520 1.00 56.11  ? 204 ASN H O   1 
ATOM   1417 C CB  . ASN A 1 204 ? 5.874   -15.100 -24.503 1.00 50.38  ? 204 ASN H CB  1 
ATOM   1418 C CG  . ASN A 1 204 ? 6.823   -14.238 -25.305 1.00 58.48  ? 204 ASN H CG  1 
ATOM   1419 O OD1 . ASN A 1 204 ? 7.166   -13.126 -24.904 1.00 60.15  ? 204 ASN H OD1 1 
ATOM   1420 N ND2 . ASN A 1 204 ? 7.245   -14.745 -26.458 1.00 59.54  ? 204 ASN H ND2 1 
ATOM   1421 N N   . THR A 1 205 ? 2.556   -16.584 -25.350 1.00 48.54  ? 205 THR H N   1 
ATOM   1422 C CA  . THR A 1 205 ? 1.826   -17.843 -25.341 1.00 48.63  ? 205 THR H CA  1 
ATOM   1423 C C   . THR A 1 205 ? 1.551   -18.285 -26.770 1.00 43.62  ? 205 THR H C   1 
ATOM   1424 O O   . THR A 1 205 ? 1.165   -17.477 -27.622 1.00 53.13  ? 205 THR H O   1 
ATOM   1425 C CB  . THR A 1 205 ? 0.513   -17.730 -24.560 1.00 49.67  ? 205 THR H CB  1 
ATOM   1426 O OG1 . THR A 1 205 ? -0.239  -16.607 -25.034 1.00 58.97  ? 205 THR H OG1 1 
ATOM   1427 C CG2 . THR A 1 205 ? 0.790   -17.563 -23.072 1.00 49.52  ? 205 THR H CG2 1 
ATOM   1428 N N   . LYS A 1 206 ? 1.766   -19.567 -27.036 1.00 45.71  ? 206 LYS H N   1 
ATOM   1429 C CA  . LYS A 1 206 ? 1.457   -20.127 -28.344 1.00 47.94  ? 206 LYS H CA  1 
ATOM   1430 C C   . LYS A 1 206 ? 0.826   -21.495 -28.154 1.00 47.20  ? 206 LYS H C   1 
ATOM   1431 O O   . LYS A 1 206 ? 1.401   -22.364 -27.492 1.00 46.37  ? 206 LYS H O   1 
ATOM   1432 C CB  . LYS A 1 206 ? 2.716   -20.184 -29.210 1.00 48.22  ? 206 LYS H CB  1 
ATOM   1433 C CG  . LYS A 1 206 ? 2.459   -20.464 -30.668 1.00 52.99  ? 206 LYS H CG  1 
ATOM   1434 C CD  . LYS A 1 206 ? 3.773   -20.495 -31.410 1.00 64.47  ? 206 LYS H CD  1 
ATOM   1435 C CE  . LYS A 1 206 ? 4.402   -19.109 -31.287 1.00 62.90  ? 206 LYS H CE  1 
ATOM   1436 N NZ  . LYS A 1 206 ? 5.467   -18.818 -32.279 1.00 58.40  ? 206 LYS H NZ  1 
ATOM   1437 N N   . VAL A 1 207 ? -0.366  -21.667 -28.721 1.00 47.52  ? 207 VAL H N   1 
ATOM   1438 C CA  . VAL A 1 207 ? -1.173  -22.864 -28.535 1.00 48.73  ? 207 VAL H CA  1 
ATOM   1439 C C   . VAL A 1 207 ? -1.497  -23.459 -29.895 1.00 49.89  ? 207 VAL H C   1 
ATOM   1440 O O   . VAL A 1 207 ? -1.846  -22.738 -30.835 1.00 53.91  ? 207 VAL H O   1 
ATOM   1441 C CB  . VAL A 1 207 ? -2.468  -22.546 -27.754 1.00 48.97  ? 207 VAL H CB  1 
ATOM   1442 C CG1 . VAL A 1 207 ? -3.331  -23.790 -27.604 1.00 47.24  ? 207 VAL H CG1 1 
ATOM   1443 C CG2 . VAL A 1 207 ? -2.137  -21.954 -26.391 1.00 48.46  ? 207 VAL H CG2 1 
ATOM   1444 N N   . ASP A 1 208 ? -1.362  -24.776 -30.004 1.00 54.60  ? 208 ASP H N   1 
ATOM   1445 C CA  . ASP A 1 208 ? -1.796  -25.523 -31.181 1.00 48.12  ? 208 ASP H CA  1 
ATOM   1446 C C   . ASP A 1 208 ? -2.902  -26.462 -30.713 1.00 54.06  ? 208 ASP H C   1 
ATOM   1447 O O   . ASP A 1 208 ? -2.625  -27.560 -30.222 1.00 59.54  ? 208 ASP H O   1 
ATOM   1448 C CB  . ASP A 1 208 ? -0.635  -26.283 -31.819 1.00 50.23  ? 208 ASP H CB  1 
ATOM   1449 C CG  . ASP A 1 208 ? 0.351   -25.364 -32.515 1.00 58.71  ? 208 ASP H CG  1 
ATOM   1450 O OD1 . ASP A 1 208 ? -0.098  -24.458 -33.246 1.00 54.61  ? 208 ASP H OD1 1 
ATOM   1451 O OD2 . ASP A 1 208 ? 1.572   -25.544 -32.325 1.00 62.47  ? 208 ASP H OD2 1 
ATOM   1452 N N   . LYS A 1 209 ? -4.151  -26.032 -30.863 1.00 49.95  ? 209 LYS H N   1 
ATOM   1453 C CA  . LYS A 1 209 ? -5.296  -26.760 -30.330 1.00 49.62  ? 209 LYS H CA  1 
ATOM   1454 C C   . LYS A 1 209 ? -5.931  -27.589 -31.435 1.00 49.04  ? 209 LYS H C   1 
ATOM   1455 O O   . LYS A 1 209 ? -6.323  -27.046 -32.472 1.00 47.28  ? 209 LYS H O   1 
ATOM   1456 C CB  . LYS A 1 209 ? -6.328  -25.804 -29.734 1.00 49.50  ? 209 LYS H CB  1 
ATOM   1457 C CG  . LYS A 1 209 ? -7.501  -26.512 -29.076 1.00 52.59  ? 209 LYS H CG  1 
ATOM   1458 C CD  . LYS A 1 209 ? -7.088  -27.267 -27.814 1.00 52.78  ? 209 LYS H CD  1 
ATOM   1459 C CE  . LYS A 1 209 ? -8.300  -27.529 -26.931 1.00 53.25  ? 209 LYS H CE  1 
ATOM   1460 N NZ  . LYS A 1 209 ? -7.979  -28.374 -25.743 1.00 61.21  ? 209 LYS H NZ  1 
ATOM   1461 N N   . ARG A 1 210 ? -6.048  -28.893 -31.198 1.00 53.98  ? 210 ARG H N   1 
ATOM   1462 C CA  . ARG A 1 210 ? -6.669  -29.815 -32.139 1.00 45.43  ? 210 ARG H CA  1 
ATOM   1463 C C   . ARG A 1 210 ? -8.172  -29.902 -31.894 1.00 45.84  ? 210 ARG H C   1 
ATOM   1464 O O   . ARG A 1 210 ? -8.617  -30.088 -30.755 1.00 54.76  ? 210 ARG H O   1 
ATOM   1465 C CB  . ARG A 1 210 ? -6.037  -31.201 -32.022 1.00 54.89  ? 210 ARG H CB  1 
ATOM   1466 C CG  . ARG A 1 210 ? -6.514  -32.195 -33.073 1.00 63.47  ? 210 ARG H CG  1 
ATOM   1467 C CD  . ARG A 1 210 ? -5.684  -33.469 -33.056 1.00 75.29  ? 210 ARG H CD  1 
ATOM   1468 N NE  . ARG A 1 210 ? -6.334  -34.551 -33.787 1.00 81.49  ? 210 ARG H NE  1 
ATOM   1469 C CZ  . ARG A 1 210 ? -5.693  -35.538 -34.398 1.00 80.15  ? 210 ARG H CZ  1 
ATOM   1470 N NH1 . ARG A 1 210 ? -4.372  -35.602 -34.408 1.00 81.30  ? 210 ARG H NH1 1 
ATOM   1471 N NH2 . ARG A 1 210 ? -6.396  -36.486 -35.011 1.00 82.50  ? 210 ARG H NH2 1 
ATOM   1472 N N   . VAL A 1 211 ? -8.947  -29.773 -32.965 1.00 47.61  ? 211 VAL H N   1 
ATOM   1473 C CA  . VAL A 1 211 ? -10.403 -29.785 -32.899 1.00 51.77  ? 211 VAL H CA  1 
ATOM   1474 C C   . VAL A 1 211 ? -10.888 -31.098 -33.499 1.00 57.58  ? 211 VAL H C   1 
ATOM   1475 O O   . VAL A 1 211 ? -10.765 -31.322 -34.710 1.00 55.24  ? 211 VAL H O   1 
ATOM   1476 C CB  . VAL A 1 211 ? -11.013 -28.581 -33.627 1.00 51.50  ? 211 VAL H CB  1 
ATOM   1477 C CG1 . VAL A 1 211 ? -12.533 -28.630 -33.552 1.00 43.64  ? 211 VAL H CG1 1 
ATOM   1478 C CG2 . VAL A 1 211 ? -10.483 -27.282 -33.039 1.00 48.09  ? 211 VAL H CG2 1 
ATOM   1479 N N   . GLU A 1 212 ? -11.449 -31.970 -32.654 1.00 64.11  ? 212 GLU H N   1 
ATOM   1480 C CA  . GLU A 1 212 ? -11.949 -33.262 -33.095 1.00 64.15  ? 212 GLU H CA  1 
ATOM   1481 C C   . GLU A 1 212 ? -13.469 -33.299 -33.005 1.00 64.41  ? 212 GLU H C   1 
ATOM   1482 O O   . GLU A 1 212 ? -14.045 -32.746 -32.060 1.00 63.87  ? 212 GLU H O   1 
ATOM   1483 C CB  . GLU A 1 212 ? -11.366 -34.410 -32.261 1.00 70.49  ? 212 GLU H CB  1 
ATOM   1484 C CG  . GLU A 1 212 ? -9.860  -34.578 -32.392 1.00 75.46  ? 212 GLU H CG  1 
ATOM   1485 C CD  . GLU A 1 212 ? -9.300  -35.586 -31.408 1.00 86.38  ? 212 GLU H CD  1 
ATOM   1486 O OE1 . GLU A 1 212 ? -9.988  -36.591 -31.130 1.00 84.98  ? 212 GLU H OE1 1 
ATOM   1487 O OE2 . GLU A 1 212 ? -8.172  -35.376 -30.915 1.00 90.29  ? 212 GLU H OE2 1 
ATOM   1488 N N   . PRO A 1 213 ? -14.144 -33.930 -33.964 1.00 65.77  ? 213 PRO H N   1 
ATOM   1489 C CA  . PRO A 1 213 ? -15.611 -33.940 -33.949 1.00 63.53  ? 213 PRO H CA  1 
ATOM   1490 C C   . PRO A 1 213 ? -16.164 -34.698 -32.753 1.00 69.34  ? 213 PRO H C   1 
ATOM   1491 O O   . PRO A 1 213 ? -15.491 -35.520 -32.127 1.00 71.37  ? 213 PRO H O   1 
ATOM   1492 C CB  . PRO A 1 213 ? -15.978 -34.642 -35.263 1.00 65.99  ? 213 PRO H CB  1 
ATOM   1493 C CG  . PRO A 1 213 ? -14.747 -34.548 -36.115 1.00 64.54  ? 213 PRO H CG  1 
ATOM   1494 C CD  . PRO A 1 213 ? -13.598 -34.592 -35.160 1.00 62.38  ? 213 PRO H CD  1 
ATOM   1495 N N   . LYS A 1 214 ? -17.424 -34.407 -32.444 1.00 72.05  ? 214 LYS H N   1 
ATOM   1496 C CA  . LYS A 1 214 ? -18.115 -35.050 -31.333 1.00 73.60  ? 214 LYS H CA  1 
ATOM   1497 C C   . LYS A 1 214 ? -19.323 -35.846 -31.816 1.00 78.85  ? 214 LYS H C   1 
ATOM   1498 O O   . LYS A 1 214 ? -19.214 -37.031 -32.129 1.00 84.29  ? 214 LYS H O   1 
ATOM   1499 C CB  . LYS A 1 214 ? -18.537 -34.004 -30.299 1.00 67.89  ? 214 LYS H CB  1 
ATOM   1500 C CG  . LYS A 1 214 ? -17.396 -33.560 -29.395 1.00 75.11  ? 214 LYS H CG  1 
ATOM   1501 C CD  . LYS A 1 214 ? -17.872 -33.224 -27.992 1.00 80.13  ? 214 LYS H CD  1 
ATOM   1502 C CE  . LYS A 1 214 ? -18.637 -31.911 -27.969 1.00 76.15  ? 214 LYS H CE  1 
ATOM   1503 N NZ  . LYS A 1 214 ? -18.842 -31.413 -26.581 1.00 70.76  ? 214 LYS H NZ  1 
ATOM   1504 N N   . GLU B 1 1   ? 41.458  -14.696 23.504  1.00 59.24  ? 1   GLU I N   1 
ATOM   1505 C CA  . GLU B 1 1   ? 42.705  -14.192 22.944  1.00 63.82  ? 1   GLU I CA  1 
ATOM   1506 C C   . GLU B 1 1   ? 42.824  -14.577 21.470  1.00 60.42  ? 1   GLU I C   1 
ATOM   1507 O O   . GLU B 1 1   ? 43.808  -14.251 20.806  1.00 61.33  ? 1   GLU I O   1 
ATOM   1508 C CB  . GLU B 1 1   ? 43.902  -14.728 23.732  1.00 66.39  ? 1   GLU I CB  1 
ATOM   1509 C CG  . GLU B 1 1   ? 45.177  -13.915 23.568  1.00 66.79  ? 1   GLU I CG  1 
ATOM   1510 C CD  . GLU B 1 1   ? 46.399  -14.788 23.368  1.00 72.30  ? 1   GLU I CD  1 
ATOM   1511 O OE1 . GLU B 1 1   ? 46.254  -16.028 23.392  1.00 70.80  ? 1   GLU I OE1 1 
ATOM   1512 O OE2 . GLU B 1 1   ? 47.503  -14.234 23.183  1.00 73.59  ? 1   GLU I OE2 1 
ATOM   1513 N N   . VAL B 1 2   ? 41.813  -15.272 20.961  1.00 53.07  ? 2   VAL I N   1 
ATOM   1514 C CA  . VAL B 1 2   ? 41.791  -15.669 19.559  1.00 57.18  ? 2   VAL I CA  1 
ATOM   1515 C C   . VAL B 1 2   ? 41.456  -14.453 18.705  1.00 49.35  ? 2   VAL I C   1 
ATOM   1516 O O   . VAL B 1 2   ? 40.446  -13.777 18.934  1.00 53.95  ? 2   VAL I O   1 
ATOM   1517 C CB  . VAL B 1 2   ? 40.780  -16.804 19.331  1.00 51.06  ? 2   VAL I CB  1 
ATOM   1518 C CG1 . VAL B 1 2   ? 40.870  -17.314 17.901  1.00 42.80  ? 2   VAL I CG1 1 
ATOM   1519 C CG2 . VAL B 1 2   ? 41.014  -17.932 20.322  1.00 50.68  ? 2   VAL I CG2 1 
ATOM   1520 N N   . GLN B 1 3   ? 42.303  -14.172 17.718  1.00 47.70  ? 3   GLN I N   1 
ATOM   1521 C CA  . GLN B 1 3   ? 42.107  -13.053 16.806  1.00 49.78  ? 3   GLN I CA  1 
ATOM   1522 C C   . GLN B 1 3   ? 42.106  -13.572 15.379  1.00 51.04  ? 3   GLN I C   1 
ATOM   1523 O O   . GLN B 1 3   ? 42.991  -14.343 14.994  1.00 49.45  ? 3   GLN I O   1 
ATOM   1524 C CB  . GLN B 1 3   ? 43.199  -11.992 16.962  1.00 47.69  ? 3   GLN I CB  1 
ATOM   1525 C CG  . GLN B 1 3   ? 42.936  -10.936 18.019  1.00 56.34  ? 3   GLN I CG  1 
ATOM   1526 C CD  . GLN B 1 3   ? 44.108  -9.986  18.171  1.00 63.26  ? 3   GLN I CD  1 
ATOM   1527 O OE1 . GLN B 1 3   ? 44.662  -9.504  17.183  1.00 67.66  ? 3   GLN I OE1 1 
ATOM   1528 N NE2 . GLN B 1 3   ? 44.510  -9.734  19.411  1.00 69.79  ? 3   GLN I NE2 1 
ATOM   1529 N N   . LEU B 1 4   ? 41.113  -13.154 14.602  1.00 45.51  ? 4   LEU I N   1 
ATOM   1530 C CA  . LEU B 1 4   ? 41.006  -13.506 13.195  1.00 39.42  ? 4   LEU I CA  1 
ATOM   1531 C C   . LEU B 1 4   ? 41.008  -12.236 12.356  1.00 42.80  ? 4   LEU I C   1 
ATOM   1532 O O   . LEU B 1 4   ? 40.368  -11.242 12.716  1.00 49.65  ? 4   LEU I O   1 
ATOM   1533 C CB  . LEU B 1 4   ? 39.735  -14.320 12.909  1.00 32.78  ? 4   LEU I CB  1 
ATOM   1534 C CG  . LEU B 1 4   ? 39.623  -15.723 13.516  1.00 37.42  ? 4   LEU I CG  1 
ATOM   1535 C CD1 . LEU B 1 4   ? 39.144  -15.676 14.962  1.00 34.45  ? 4   LEU I CD1 1 
ATOM   1536 C CD2 . LEU B 1 4   ? 38.713  -16.602 12.673  1.00 35.88  ? 4   LEU I CD2 1 
ATOM   1537 N N   . GLN B 1 5   ? 41.731  -12.277 11.237  1.00 42.28  ? 5   GLN I N   1 
ATOM   1538 C CA  . GLN B 1 5   ? 41.856  -11.134 10.340  1.00 42.82  ? 5   GLN I CA  1 
ATOM   1539 C C   . GLN B 1 5   ? 41.613  -11.570 8.905   1.00 45.14  ? 5   GLN I C   1 
ATOM   1540 O O   . GLN B 1 5   ? 42.264  -12.498 8.419   1.00 42.05  ? 5   GLN I O   1 
ATOM   1541 C CB  . GLN B 1 5   ? 43.244  -10.491 10.445  1.00 42.41  ? 5   GLN I CB  1 
ATOM   1542 C CG  . GLN B 1 5   ? 43.450  -9.289  9.524   1.00 50.95  ? 5   GLN I CG  1 
ATOM   1543 C CD  . GLN B 1 5   ? 42.549  -8.117  9.852   1.00 58.19  ? 5   GLN I CD  1 
ATOM   1544 O OE1 . GLN B 1 5   ? 41.619  -7.796  9.106   1.00 59.47  ? 5   GLN I OE1 1 
ATOM   1545 N NE2 . GLN B 1 5   ? 42.844  -7.447  10.958  1.00 60.24  ? 5   GLN I NE2 1 
ATOM   1546 N N   . GLU B 1 6   ? 40.698  -10.884 8.226   1.00 46.86  ? 6   GLU I N   1 
ATOM   1547 C CA  . GLU B 1 6   ? 40.451  -11.129 6.814   1.00 39.30  ? 6   GLU I CA  1 
ATOM   1548 C C   . GLU B 1 6   ? 41.344  -10.239 5.959   1.00 39.07  ? 6   GLU I C   1 
ATOM   1549 O O   . GLU B 1 6   ? 41.690  -9.117  6.340   1.00 40.46  ? 6   GLU I O   1 
ATOM   1550 C CB  . GLU B 1 6   ? 38.985  -10.878 6.449   1.00 38.19  ? 6   GLU I CB  1 
ATOM   1551 C CG  . GLU B 1 6   ? 37.973  -11.751 7.174   1.00 37.59  ? 6   GLU I CG  1 
ATOM   1552 C CD  . GLU B 1 6   ? 37.522  -11.158 8.493   1.00 43.27  ? 6   GLU I CD  1 
ATOM   1553 O OE1 . GLU B 1 6   ? 38.090  -10.129 8.912   1.00 36.90  ? 6   GLU I OE1 1 
ATOM   1554 O OE2 . GLU B 1 6   ? 36.589  -11.717 9.107   1.00 40.91  ? 6   GLU I OE2 1 
ATOM   1555 N N   . SER B 1 7   ? 41.711  -10.757 4.789   1.00 38.36  ? 7   SER I N   1 
ATOM   1556 C CA  . SER B 1 7   ? 42.502  -10.008 3.827   1.00 45.28  ? 7   SER I CA  1 
ATOM   1557 C C   . SER B 1 7   ? 42.182  -10.519 2.431   1.00 40.68  ? 7   SER I C   1 
ATOM   1558 O O   . SER B 1 7   ? 41.750  -11.660 2.247   1.00 44.82  ? 7   SER I O   1 
ATOM   1559 C CB  . SER B 1 7   ? 44.005  -10.118 4.117   1.00 42.45  ? 7   SER I CB  1 
ATOM   1560 O OG  . SER B 1 7   ? 44.435  -11.468 4.100   1.00 41.66  ? 7   SER I OG  1 
ATOM   1561 N N   . GLY B 1 8   ? 42.402  -9.655  1.444   1.00 45.21  ? 8   GLY I N   1 
ATOM   1562 C CA  . GLY B 1 8   ? 42.104  -9.980  0.072   1.00 43.84  ? 8   GLY I CA  1 
ATOM   1563 C C   . GLY B 1 8   ? 41.492  -8.808  -0.666  1.00 44.34  ? 8   GLY I C   1 
ATOM   1564 O O   . GLY B 1 8   ? 41.264  -7.735  -0.098  1.00 45.24  ? 8   GLY I O   1 
ATOM   1565 N N   . PRO B 1 9   ? 41.214  -8.993  -1.954  1.00 51.04  ? 9   PRO I N   1 
ATOM   1566 C CA  . PRO B 1 9   ? 40.668  -7.891  -2.753  1.00 47.47  ? 9   PRO I CA  1 
ATOM   1567 C C   . PRO B 1 9   ? 39.229  -7.579  -2.372  1.00 47.20  ? 9   PRO I C   1 
ATOM   1568 O O   . PRO B 1 9   ? 38.437  -8.473  -2.068  1.00 49.89  ? 9   PRO I O   1 
ATOM   1569 C CB  . PRO B 1 9   ? 40.766  -8.416  -4.189  1.00 47.85  ? 9   PRO I CB  1 
ATOM   1570 C CG  . PRO B 1 9   ? 40.668  -9.900  -4.039  1.00 55.50  ? 9   PRO I CG  1 
ATOM   1571 C CD  . PRO B 1 9   ? 41.370  -10.228 -2.744  1.00 50.03  ? 9   PRO I CD  1 
ATOM   1572 N N   . GLY B 1 10  ? 38.901  -6.290  -2.388  1.00 45.29  ? 10  GLY I N   1 
ATOM   1573 C CA  . GLY B 1 10  ? 37.556  -5.821  -2.147  1.00 41.25  ? 10  GLY I CA  1 
ATOM   1574 C C   . GLY B 1 10  ? 36.718  -5.627  -3.387  1.00 39.72  ? 10  GLY I C   1 
ATOM   1575 O O   . GLY B 1 10  ? 35.538  -5.277  -3.282  1.00 41.18  ? 10  GLY I O   1 
ATOM   1576 N N   . LEU B 1 11  ? 37.293  -5.849  -4.567  1.00 43.84  ? 11  LEU I N   1 
ATOM   1577 C CA  . LEU B 1 11  ? 36.596  -5.679  -5.837  1.00 37.79  ? 11  LEU I CA  1 
ATOM   1578 C C   . LEU B 1 11  ? 36.888  -6.883  -6.717  1.00 38.17  ? 11  LEU I C   1 
ATOM   1579 O O   . LEU B 1 11  ? 38.052  -7.163  -7.021  1.00 38.55  ? 11  LEU I O   1 
ATOM   1580 C CB  . LEU B 1 11  ? 37.034  -4.392  -6.543  1.00 38.94  ? 11  LEU I CB  1 
ATOM   1581 C CG  . LEU B 1 11  ? 37.007  -3.076  -5.765  1.00 47.36  ? 11  LEU I CG  1 
ATOM   1582 C CD1 . LEU B 1 11  ? 37.587  -1.953  -6.613  1.00 40.21  ? 11  LEU I CD1 1 
ATOM   1583 C CD2 . LEU B 1 11  ? 35.598  -2.738  -5.315  1.00 42.54  ? 11  LEU I CD2 1 
ATOM   1584 N N   . VAL B 1 12  ? 35.838  -7.596  -7.119  1.00 38.41  ? 12  VAL I N   1 
ATOM   1585 C CA  . VAL B 1 12  ? 35.957  -8.724  -8.035  1.00 39.45  ? 12  VAL I CA  1 
ATOM   1586 C C   . VAL B 1 12  ? 34.993  -8.506  -9.193  1.00 43.51  ? 12  VAL I C   1 
ATOM   1587 O O   . VAL B 1 12  ? 33.863  -8.046  -8.995  1.00 42.62  ? 12  VAL I O   1 
ATOM   1588 C CB  . VAL B 1 12  ? 35.665  -10.066 -7.327  1.00 44.43  ? 12  VAL I CB  1 
ATOM   1589 C CG1 . VAL B 1 12  ? 35.872  -11.236 -8.278  1.00 42.36  ? 12  VAL I CG1 1 
ATOM   1590 C CG2 . VAL B 1 12  ? 36.539  -10.222 -6.090  1.00 34.47  ? 12  VAL I CG2 1 
ATOM   1591 N N   . LYS B 1 13  ? 35.441  -8.835  -10.403 1.00 41.66  ? 13  LYS I N   1 
ATOM   1592 C CA  . LYS B 1 13  ? 34.589  -8.709  -11.573 1.00 40.66  ? 13  LYS I CA  1 
ATOM   1593 C C   . LYS B 1 13  ? 33.660  -9.916  -11.687 1.00 41.20  ? 13  LYS I C   1 
ATOM   1594 O O   . LYS B 1 13  ? 34.002  -11.014 -11.238 1.00 42.22  ? 13  LYS I O   1 
ATOM   1595 C CB  . LYS B 1 13  ? 35.430  -8.569  -12.838 1.00 39.92  ? 13  LYS I CB  1 
ATOM   1596 C CG  . LYS B 1 13  ? 36.447  -7.447  -12.758 1.00 42.89  ? 13  LYS I CG  1 
ATOM   1597 C CD  . LYS B 1 13  ? 35.949  -6.213  -13.491 1.00 43.65  ? 13  LYS I CD  1 
ATOM   1598 C CE  . LYS B 1 13  ? 36.638  -4.959  -12.980 1.00 44.18  ? 13  LYS I CE  1 
ATOM   1599 N NZ  . LYS B 1 13  ? 36.126  -3.735  -13.655 1.00 52.46  ? 13  LYS I NZ  1 
ATOM   1600 N N   . PRO B 1 14  ? 32.470  -9.730  -12.261 1.00 40.70  ? 14  PRO I N   1 
ATOM   1601 C CA  . PRO B 1 14  ? 31.534  -10.852 -12.403 1.00 42.83  ? 14  PRO I CA  1 
ATOM   1602 C C   . PRO B 1 14  ? 32.126  -12.008 -13.197 1.00 46.06  ? 14  PRO I C   1 
ATOM   1603 O O   . PRO B 1 14  ? 32.929  -11.818 -14.116 1.00 40.39  ? 14  PRO I O   1 
ATOM   1604 C CB  . PRO B 1 14  ? 30.340  -10.226 -13.135 1.00 41.77  ? 14  PRO I CB  1 
ATOM   1605 C CG  . PRO B 1 14  ? 30.411  -8.783  -12.791 1.00 38.84  ? 14  PRO I CG  1 
ATOM   1606 C CD  . PRO B 1 14  ? 31.873  -8.458  -12.701 1.00 38.87  ? 14  PRO I CD  1 
ATOM   1607 N N   . SER B 1 15  ? 31.713  -13.222 -12.808 1.00 46.21  ? 15  SER I N   1 
ATOM   1608 C CA  . SER B 1 15  ? 32.144  -14.502 -13.372 1.00 44.26  ? 15  SER I CA  1 
ATOM   1609 C C   . SER B 1 15  ? 33.575  -14.873 -12.990 1.00 37.96  ? 15  SER I C   1 
ATOM   1610 O O   . SER B 1 15  ? 34.035  -15.974 -13.315 1.00 48.35  ? 15  SER I O   1 
ATOM   1611 C CB  . SER B 1 15  ? 32.000  -14.503 -14.898 1.00 47.53  ? 15  SER I CB  1 
ATOM   1612 O OG  . SER B 1 15  ? 32.999  -13.701 -15.507 1.00 47.31  ? 15  SER I OG  1 
ATOM   1613 N N   . GLN B 1 16  ? 34.289  -13.983 -12.305 1.00 41.00  ? 16  GLN I N   1 
ATOM   1614 C CA  . GLN B 1 16  ? 35.628  -14.313 -11.843 1.00 42.95  ? 16  GLN I CA  1 
ATOM   1615 C C   . GLN B 1 16  ? 35.547  -14.954 -10.457 1.00 38.68  ? 16  GLN I C   1 
ATOM   1616 O O   . GLN B 1 16  ? 34.469  -15.321 -9.981  1.00 36.00  ? 16  GLN I O   1 
ATOM   1617 C CB  . GLN B 1 16  ? 36.518  -13.072 -11.867 1.00 38.70  ? 16  GLN I CB  1 
ATOM   1618 C CG  . GLN B 1 16  ? 36.794  -12.525 -13.267 1.00 46.13  ? 16  GLN I CG  1 
ATOM   1619 C CD  . GLN B 1 16  ? 37.488  -13.528 -14.175 1.00 45.93  ? 16  GLN I CD  1 
ATOM   1620 O OE1 . GLN B 1 16  ? 38.716  -13.579 -14.234 1.00 45.89  ? 16  GLN I OE1 1 
ATOM   1621 N NE2 . GLN B 1 16  ? 36.704  -14.323 -14.896 1.00 43.12  ? 16  GLN I NE2 1 
ATOM   1622 N N   . SER B 1 17  ? 36.691  -15.090 -9.790  1.00 39.66  ? 17  SER I N   1 
ATOM   1623 C CA  . SER B 1 17  ? 36.787  -15.800 -8.522  1.00 49.33  ? 17  SER I CA  1 
ATOM   1624 C C   . SER B 1 17  ? 37.154  -14.840 -7.398  1.00 41.64  ? 17  SER I C   1 
ATOM   1625 O O   . SER B 1 17  ? 38.008  -13.964 -7.567  1.00 44.74  ? 17  SER I O   1 
ATOM   1626 C CB  . SER B 1 17  ? 37.812  -16.937 -8.600  1.00 44.71  ? 17  SER I CB  1 
ATOM   1627 O OG  . SER B 1 17  ? 39.127  -16.434 -8.755  1.00 59.16  ? 17  SER I OG  1 
ATOM   1628 N N   . LEU B 1 18  ? 36.509  -15.022 -6.249  1.00 48.26  ? 18  LEU I N   1 
ATOM   1629 C CA  . LEU B 1 18  ? 36.771  -14.244 -5.045  1.00 42.82  ? 18  LEU I CA  1 
ATOM   1630 C C   . LEU B 1 18  ? 37.658  -15.062 -4.114  1.00 41.21  ? 18  LEU I C   1 
ATOM   1631 O O   . LEU B 1 18  ? 37.294  -16.180 -3.727  1.00 44.57  ? 18  LEU I O   1 
ATOM   1632 C CB  . LEU B 1 18  ? 35.464  -13.864 -4.348  1.00 42.51  ? 18  LEU I CB  1 
ATOM   1633 C CG  . LEU B 1 18  ? 35.566  -13.400 -2.895  1.00 46.73  ? 18  LEU I CG  1 
ATOM   1634 C CD1 . LEU B 1 18  ? 36.348  -12.098 -2.797  1.00 43.78  ? 18  LEU I CD1 1 
ATOM   1635 C CD2 . LEU B 1 18  ? 34.181  -13.246 -2.283  1.00 43.99  ? 18  LEU I CD2 1 
ATOM   1636 N N   . SER B 1 19  ? 38.819  -14.503 -3.767  1.00 40.07  ? 19  SER I N   1 
ATOM   1637 C CA  . SER B 1 19  ? 39.819  -15.159 -2.933  1.00 41.64  ? 19  SER I CA  1 
ATOM   1638 C C   . SER B 1 19  ? 39.987  -14.358 -1.651  1.00 43.28  ? 19  SER I C   1 
ATOM   1639 O O   . SER B 1 19  ? 40.267  -13.155 -1.702  1.00 43.56  ? 19  SER I O   1 
ATOM   1640 C CB  . SER B 1 19  ? 41.156  -15.258 -3.668  1.00 38.10  ? 19  SER I CB  1 
ATOM   1641 O OG  . SER B 1 19  ? 41.265  -16.468 -4.387  1.00 47.37  ? 19  SER I OG  1 
ATOM   1642 N N   . LEU B 1 20  ? 39.818  -15.020 -0.507  1.00 42.68  ? 20  LEU I N   1 
ATOM   1643 C CA  . LEU B 1 20  ? 39.971  -14.372 0.790   1.00 41.85  ? 20  LEU I CA  1 
ATOM   1644 C C   . LEU B 1 20  ? 40.837  -15.218 1.713   1.00 37.99  ? 20  LEU I C   1 
ATOM   1645 O O   . LEU B 1 20  ? 40.750  -16.448 1.706   1.00 37.48  ? 20  LEU I O   1 
ATOM   1646 C CB  . LEU B 1 20  ? 38.613  -14.108 1.445   1.00 43.27  ? 20  LEU I CB  1 
ATOM   1647 C CG  . LEU B 1 20  ? 37.762  -13.024 0.783   1.00 40.89  ? 20  LEU I CG  1 
ATOM   1648 C CD1 . LEU B 1 20  ? 36.433  -12.881 1.499   1.00 39.53  ? 20  LEU I CD1 1 
ATOM   1649 C CD2 . LEU B 1 20  ? 38.504  -11.696 0.763   1.00 38.27  ? 20  LEU I CD2 1 
ATOM   1650 N N   . THR B 1 21  ? 41.679  -14.551 2.499   1.00 34.42  ? 21  THR I N   1 
ATOM   1651 C CA  . THR B 1 21  ? 42.556  -15.198 3.464   1.00 38.82  ? 21  THR I CA  1 
ATOM   1652 C C   . THR B 1 21  ? 42.164  -14.774 4.873   1.00 38.55  ? 21  THR I C   1 
ATOM   1653 O O   . THR B 1 21  ? 41.866  -13.601 5.112   1.00 42.36  ? 21  THR I O   1 
ATOM   1654 C CB  . THR B 1 21  ? 44.022  -14.833 3.202   1.00 42.91  ? 21  THR I CB  1 
ATOM   1655 O OG1 . THR B 1 21  ? 44.417  -15.333 1.918   1.00 44.00  ? 21  THR I OG1 1 
ATOM   1656 C CG2 . THR B 1 21  ? 44.931  -15.416 4.279   1.00 37.50  ? 21  THR I CG2 1 
ATOM   1657 N N   . CYS B 1 22  ? 42.145  -15.724 5.805   1.00 40.84  ? 22  CYS I N   1 
ATOM   1658 C CA  . CYS B 1 22  ? 41.912  -15.431 7.212   1.00 37.53  ? 22  CYS I CA  1 
ATOM   1659 C C   . CYS B 1 22  ? 43.129  -15.892 7.998   1.00 39.98  ? 22  CYS I C   1 
ATOM   1660 O O   . CYS B 1 22  ? 43.452  -17.089 8.003   1.00 44.41  ? 22  CYS I O   1 
ATOM   1661 C CB  . CYS B 1 22  ? 40.647  -16.120 7.720   1.00 38.36  ? 22  CYS I CB  1 
ATOM   1662 S SG  . CYS B 1 22  ? 40.196  -15.731 9.428   1.00 42.30  ? 22  CYS I SG  1 
ATOM   1663 N N   . SER B 1 23  ? 43.800  -14.937 8.638   1.00 39.13  ? 23  SER I N   1 
ATOM   1664 C CA  . SER B 1 23  ? 44.947  -15.191 9.499   1.00 42.84  ? 23  SER I CA  1 
ATOM   1665 C C   . SER B 1 23  ? 44.475  -15.261 10.947  1.00 42.36  ? 23  SER I C   1 
ATOM   1666 O O   . SER B 1 23  ? 43.814  -14.335 11.434  1.00 41.04  ? 23  SER I O   1 
ATOM   1667 C CB  . SER B 1 23  ? 46.007  -14.104 9.327   1.00 41.57  ? 23  SER I CB  1 
ATOM   1668 O OG  . SER B 1 23  ? 46.340  -13.923 7.963   1.00 42.11  ? 23  SER I OG  1 
ATOM   1669 N N   . VAL B 1 24  ? 44.796  -16.365 11.619  1.00 46.47  ? 24  VAL I N   1 
ATOM   1670 C CA  . VAL B 1 24  ? 44.403  -16.607 13.002  1.00 43.18  ? 24  VAL I CA  1 
ATOM   1671 C C   . VAL B 1 24  ? 45.640  -16.508 13.884  1.00 46.47  ? 24  VAL I C   1 
ATOM   1672 O O   . VAL B 1 24  ? 46.689  -17.078 13.559  1.00 49.06  ? 24  VAL I O   1 
ATOM   1673 C CB  . VAL B 1 24  ? 43.727  -17.980 13.161  1.00 42.33  ? 24  VAL I CB  1 
ATOM   1674 C CG1 . VAL B 1 24  ? 43.054  -18.084 14.519  1.00 40.62  ? 24  VAL I CG1 1 
ATOM   1675 C CG2 . VAL B 1 24  ? 42.725  -18.212 12.041  1.00 33.38  ? 24  VAL I CG2 1 
ATOM   1676 N N   . ILE B 1 25  ? 45.519  -15.789 14.999  1.00 48.21  ? 25  ILE I N   1 
ATOM   1677 C CA  . ILE B 1 25  ? 46.567  -15.741 16.011  1.00 52.19  ? 25  ILE I CA  1 
ATOM   1678 C C   . ILE B 1 25  ? 45.947  -16.016 17.374  1.00 51.48  ? 25  ILE I C   1 
ATOM   1679 O O   . ILE B 1 25  ? 44.772  -15.720 17.616  1.00 52.16  ? 25  ILE I O   1 
ATOM   1680 C CB  . ILE B 1 25  ? 47.329  -14.394 16.028  1.00 51.14  ? 25  ILE I CB  1 
ATOM   1681 C CG1 . ILE B 1 25  ? 46.398  -13.250 16.428  1.00 53.91  ? 25  ILE I CG1 1 
ATOM   1682 C CG2 . ILE B 1 25  ? 47.977  -14.120 14.676  1.00 53.56  ? 25  ILE I CG2 1 
ATOM   1683 C CD1 . ILE B 1 25  ? 47.120  -12.015 16.921  1.00 53.40  ? 25  ILE I CD1 1 
ATOM   1684 N N   . GLY B 1 26  ? 46.751  -16.594 18.268  1.00 50.00  ? 26  GLY I N   1 
ATOM   1685 C CA  . GLY B 1 26  ? 46.330  -16.889 19.620  1.00 49.97  ? 26  GLY I CA  1 
ATOM   1686 C C   . GLY B 1 26  ? 45.762  -18.275 19.834  1.00 50.15  ? 26  GLY I C   1 
ATOM   1687 O O   . GLY B 1 26  ? 45.485  -18.641 20.984  1.00 49.54  ? 26  GLY I O   1 
ATOM   1688 N N   . TYR B 1 27  ? 45.593  -19.060 18.773  1.00 47.74  ? 27  TYR I N   1 
ATOM   1689 C CA  . TYR B 1 27  ? 45.028  -20.399 18.861  1.00 39.82  ? 27  TYR I CA  1 
ATOM   1690 C C   . TYR B 1 27  ? 45.278  -21.098 17.534  1.00 45.64  ? 27  TYR I C   1 
ATOM   1691 O O   . TYR B 1 27  ? 45.215  -20.464 16.480  1.00 46.81  ? 27  TYR I O   1 
ATOM   1692 C CB  . TYR B 1 27  ? 43.523  -20.332 19.165  1.00 41.56  ? 27  TYR I CB  1 
ATOM   1693 C CG  . TYR B 1 27  ? 42.830  -21.662 19.374  1.00 44.91  ? 27  TYR I CG  1 
ATOM   1694 C CD1 . TYR B 1 27  ? 42.965  -22.364 20.565  1.00 38.67  ? 27  TYR I CD1 1 
ATOM   1695 C CD2 . TYR B 1 27  ? 42.013  -22.201 18.389  1.00 41.84  ? 27  TYR I CD2 1 
ATOM   1696 C CE1 . TYR B 1 27  ? 42.320  -23.575 20.759  1.00 37.17  ? 27  TYR I CE1 1 
ATOM   1697 C CE2 . TYR B 1 27  ? 41.368  -23.410 18.574  1.00 43.88  ? 27  TYR I CE2 1 
ATOM   1698 C CZ  . TYR B 1 27  ? 41.523  -24.091 19.759  1.00 46.92  ? 27  TYR I CZ  1 
ATOM   1699 O OH  . TYR B 1 27  ? 40.880  -25.294 19.946  1.00 38.86  ? 27  TYR I OH  1 
ATOM   1700 N N   . SER B 1 28  ? 45.563  -22.395 17.589  1.00 41.74  ? 28  SER I N   1 
ATOM   1701 C CA  . SER B 1 28  ? 45.851  -23.134 16.369  1.00 45.97  ? 28  SER I CA  1 
ATOM   1702 C C   . SER B 1 28  ? 44.555  -23.596 15.714  1.00 46.45  ? 28  SER I C   1 
ATOM   1703 O O   . SER B 1 28  ? 43.544  -23.823 16.384  1.00 49.23  ? 28  SER I O   1 
ATOM   1704 C CB  . SER B 1 28  ? 46.749  -24.339 16.666  1.00 48.55  ? 28  SER I CB  1 
ATOM   1705 O OG  . SER B 1 28  ? 46.838  -25.198 15.542  1.00 51.56  ? 28  SER I OG  1 
ATOM   1706 N N   . ILE B 1 29  ? 44.598  -23.767 14.388  1.00 49.03  ? 29  ILE I N   1 
ATOM   1707 C CA  . ILE B 1 29  ? 43.415  -24.205 13.656  1.00 46.88  ? 29  ILE I CA  1 
ATOM   1708 C C   . ILE B 1 29  ? 43.349  -25.717 13.546  1.00 43.10  ? 29  ILE I C   1 
ATOM   1709 O O   . ILE B 1 29  ? 42.373  -26.251 13.001  1.00 43.53  ? 29  ILE I O   1 
ATOM   1710 C CB  . ILE B 1 29  ? 43.341  -23.576 12.248  1.00 48.01  ? 29  ILE I CB  1 
ATOM   1711 C CG1 . ILE B 1 29  ? 44.562  -23.957 11.413  1.00 50.34  ? 29  ILE I CG1 1 
ATOM   1712 C CG2 . ILE B 1 29  ? 43.187  -22.065 12.345  1.00 41.25  ? 29  ILE I CG2 1 
ATOM   1713 C CD1 . ILE B 1 29  ? 44.523  -23.405 10.003  1.00 46.12  ? 29  ILE I CD1 1 
ATOM   1714 N N   . THR B 1 30  ? 44.363  -26.424 14.037  1.00 45.92  ? 30  THR I N   1 
ATOM   1715 C CA  . THR B 1 30  ? 44.362  -27.876 14.107  1.00 47.28  ? 30  THR I CA  1 
ATOM   1716 C C   . THR B 1 30  ? 44.030  -28.385 15.502  1.00 44.48  ? 30  THR I C   1 
ATOM   1717 O O   . THR B 1 30  ? 44.055  -29.598 15.730  1.00 45.83  ? 30  THR I O   1 
ATOM   1718 C CB  . THR B 1 30  ? 45.721  -28.427 13.665  1.00 44.02  ? 30  THR I CB  1 
ATOM   1719 O OG1 . THR B 1 30  ? 46.741  -27.955 14.554  1.00 43.44  ? 30  THR I OG1 1 
ATOM   1720 C CG2 . THR B 1 30  ? 46.042  -27.975 12.250  1.00 43.64  ? 30  THR I CG2 1 
ATOM   1721 N N   . SER B 1 31  ? 43.723  -27.485 16.440  1.00 45.00  ? 31  SER I N   1 
ATOM   1722 C CA  . SER B 1 31  ? 43.391  -27.894 17.799  1.00 44.41  ? 31  SER I CA  1 
ATOM   1723 C C   . SER B 1 31  ? 41.929  -28.309 17.913  1.00 43.59  ? 31  SER I C   1 
ATOM   1724 O O   . SER B 1 31  ? 41.622  -29.382 18.441  1.00 48.02  ? 31  SER I O   1 
ATOM   1725 C CB  . SER B 1 31  ? 43.704  -26.763 18.781  1.00 39.63  ? 31  SER I CB  1 
ATOM   1726 O OG  . SER B 1 31  ? 45.097  -26.514 18.845  1.00 44.49  ? 31  SER I OG  1 
ATOM   1727 N N   . GLY B 1 32  ? 41.018  -27.472 17.428  1.00 44.02  ? 32  GLY I N   1 
ATOM   1728 C CA  . GLY B 1 32  ? 39.603  -27.783 17.512  1.00 42.59  ? 32  GLY I CA  1 
ATOM   1729 C C   . GLY B 1 32  ? 38.786  -26.772 16.739  1.00 45.58  ? 32  GLY I C   1 
ATOM   1730 O O   . GLY B 1 32  ? 39.324  -25.903 16.046  1.00 46.84  ? 32  GLY I O   1 
ATOM   1731 N N   . TYR B 1 33  ? 37.463  -26.920 16.861  1.00 44.44  ? 33  TYR I N   1 
ATOM   1732 C CA  . TYR B 1 33  ? 36.470  -26.015 16.286  1.00 46.57  ? 33  TYR I CA  1 
ATOM   1733 C C   . TYR B 1 33  ? 36.386  -26.093 14.765  1.00 45.43  ? 33  TYR I C   1 
ATOM   1734 O O   . TYR B 1 33  ? 37.375  -26.394 14.090  1.00 47.48  ? 33  TYR I O   1 
ATOM   1735 C CB  . TYR B 1 33  ? 36.749  -24.562 16.690  1.00 42.77  ? 33  TYR I CB  1 
ATOM   1736 C CG  . TYR B 1 33  ? 36.351  -24.200 18.100  1.00 45.92  ? 33  TYR I CG  1 
ATOM   1737 C CD1 . TYR B 1 33  ? 35.057  -23.787 18.392  1.00 43.79  ? 33  TYR I CD1 1 
ATOM   1738 C CD2 . TYR B 1 33  ? 37.273  -24.246 19.136  1.00 47.39  ? 33  TYR I CD2 1 
ATOM   1739 C CE1 . TYR B 1 33  ? 34.689  -23.445 19.678  1.00 47.26  ? 33  TYR I CE1 1 
ATOM   1740 C CE2 . TYR B 1 33  ? 36.915  -23.906 20.425  1.00 47.05  ? 33  TYR I CE2 1 
ATOM   1741 C CZ  . TYR B 1 33  ? 35.622  -23.506 20.692  1.00 50.56  ? 33  TYR I CZ  1 
ATOM   1742 O OH  . TYR B 1 33  ? 35.263  -23.167 21.976  1.00 49.20  ? 33  TYR I OH  1 
ATOM   1743 N N   . TYR B 1 34  ? 35.199  -25.826 14.225  1.00 44.29  ? 34  TYR I N   1 
ATOM   1744 C CA  . TYR B 1 34  ? 35.065  -25.493 12.817  1.00 39.05  ? 34  TYR I CA  1 
ATOM   1745 C C   . TYR B 1 34  ? 35.501  -24.054 12.581  1.00 39.34  ? 34  TYR I C   1 
ATOM   1746 O O   . TYR B 1 34  ? 35.300  -23.173 13.422  1.00 42.10  ? 34  TYR I O   1 
ATOM   1747 C CB  . TYR B 1 34  ? 33.624  -25.664 12.334  1.00 39.69  ? 34  TYR I CB  1 
ATOM   1748 C CG  . TYR B 1 34  ? 33.237  -27.069 11.938  1.00 44.61  ? 34  TYR I CG  1 
ATOM   1749 C CD1 . TYR B 1 34  ? 33.772  -27.660 10.801  1.00 41.79  ? 34  TYR I CD1 1 
ATOM   1750 C CD2 . TYR B 1 34  ? 32.308  -27.789 12.675  1.00 42.29  ? 34  TYR I CD2 1 
ATOM   1751 C CE1 . TYR B 1 34  ? 33.413  -28.939 10.425  1.00 41.01  ? 34  TYR I CE1 1 
ATOM   1752 C CE2 . TYR B 1 34  ? 31.940  -29.069 12.306  1.00 45.95  ? 34  TYR I CE2 1 
ATOM   1753 C CZ  . TYR B 1 34  ? 32.497  -29.640 11.180  1.00 44.80  ? 34  TYR I CZ  1 
ATOM   1754 O OH  . TYR B 1 34  ? 32.132  -30.914 10.808  1.00 41.80  ? 34  TYR I OH  1 
ATOM   1755 N N   . TRP B 1 35  ? 36.112  -23.824 11.428  1.00 39.76  ? 35  TRP I N   1 
ATOM   1756 C CA  . TRP B 1 35  ? 36.565  -22.499 11.028  1.00 37.08  ? 35  TRP I CA  1 
ATOM   1757 C C   . TRP B 1 35  ? 35.720  -22.096 9.823   1.00 40.69  ? 35  TRP I C   1 
ATOM   1758 O O   . TRP B 1 35  ? 35.814  -22.718 8.757   1.00 41.69  ? 35  TRP I O   1 
ATOM   1759 C CB  . TRP B 1 35  ? 38.059  -22.535 10.721  1.00 36.59  ? 35  TRP I CB  1 
ATOM   1760 C CG  . TRP B 1 35  ? 38.855  -22.873 11.957  1.00 40.43  ? 35  TRP I CG  1 
ATOM   1761 C CD1 . TRP B 1 35  ? 39.157  -24.127 12.407  1.00 39.54  ? 35  TRP I CD1 1 
ATOM   1762 C CD2 . TRP B 1 35  ? 39.410  -21.962 12.915  1.00 35.06  ? 35  TRP I CD2 1 
ATOM   1763 N NE1 . TRP B 1 35  ? 39.877  -24.054 13.573  1.00 42.01  ? 35  TRP I NE1 1 
ATOM   1764 C CE2 . TRP B 1 35  ? 40.048  -22.736 13.907  1.00 40.05  ? 35  TRP I CE2 1 
ATOM   1765 C CE3 . TRP B 1 35  ? 39.442  -20.569 13.024  1.00 36.05  ? 35  TRP I CE3 1 
ATOM   1766 C CZ2 . TRP B 1 35  ? 40.705  -22.164 14.994  1.00 37.63  ? 35  TRP I CZ2 1 
ATOM   1767 C CZ3 . TRP B 1 35  ? 40.096  -20.003 14.105  1.00 38.39  ? 35  TRP I CZ3 1 
ATOM   1768 C CH2 . TRP B 1 35  ? 40.720  -20.800 15.073  1.00 40.17  ? 35  TRP I CH2 1 
ATOM   1769 N N   . ASN B 1 36  A 34.886  -21.073 10.001  1.00 42.04  ? 35  ASN I N   1 
ATOM   1770 C CA  . ASN B 1 36  A 33.779  -20.777 9.103   1.00 35.80  ? 35  ASN I CA  1 
ATOM   1771 C C   . ASN B 1 36  A 34.000  -19.503 8.300   1.00 37.05  ? 35  ASN I C   1 
ATOM   1772 O O   . ASN B 1 36  A 34.658  -18.560 8.753   1.00 34.88  ? 35  ASN I O   1 
ATOM   1773 C CB  . ASN B 1 36  A 32.469  -20.624 9.881   1.00 33.24  ? 35  ASN I CB  1 
ATOM   1774 C CG  . ASN B 1 36  A 32.191  -21.792 10.790  1.00 40.24  ? 35  ASN I CG  1 
ATOM   1775 O OD1 . ASN B 1 36  A 31.631  -22.796 10.362  1.00 39.34  ? 35  ASN I OD1 1 
ATOM   1776 N ND2 . ASN B 1 36  A 32.574  -21.668 12.056  1.00 36.08  ? 35  ASN I ND2 1 
ATOM   1777 N N   . TRP B 1 37  ? 33.407  -19.491 7.107   1.00 33.96  ? 36  TRP I N   1 
ATOM   1778 C CA  . TRP B 1 37  ? 33.170  -18.284 6.326   1.00 33.04  ? 36  TRP I CA  1 
ATOM   1779 C C   . TRP B 1 37  ? 31.670  -18.017 6.307   1.00 34.73  ? 36  TRP I C   1 
ATOM   1780 O O   . TRP B 1 37  ? 30.888  -18.896 5.906   1.00 34.40  ? 36  TRP I O   1 
ATOM   1781 C CB  . TRP B 1 37  ? 33.706  -18.426 4.902   1.00 34.81  ? 36  TRP I CB  1 
ATOM   1782 C CG  . TRP B 1 37  ? 35.190  -18.340 4.820   1.00 35.13  ? 36  TRP I CG  1 
ATOM   1783 C CD1 . TRP B 1 37  ? 36.058  -19.375 4.651   1.00 32.70  ? 36  TRP I CD1 1 
ATOM   1784 C CD2 . TRP B 1 37  ? 35.990  -17.157 4.928   1.00 35.70  ? 36  TRP I CD2 1 
ATOM   1785 N NE1 . TRP B 1 37  ? 37.350  -18.911 4.631   1.00 36.10  ? 36  TRP I NE1 1 
ATOM   1786 C CE2 . TRP B 1 37  ? 37.336  -17.551 4.804   1.00 34.19  ? 36  TRP I CE2 1 
ATOM   1787 C CE3 . TRP B 1 37  ? 35.699  -15.802 5.114   1.00 35.54  ? 36  TRP I CE3 1 
ATOM   1788 C CZ2 . TRP B 1 37  ? 38.389  -16.641 4.858   1.00 33.09  ? 36  TRP I CZ2 1 
ATOM   1789 C CZ3 . TRP B 1 37  ? 36.747  -14.899 5.167   1.00 36.27  ? 36  TRP I CZ3 1 
ATOM   1790 C CH2 . TRP B 1 37  ? 38.074  -15.323 5.039   1.00 39.45  ? 36  TRP I CH2 1 
ATOM   1791 N N   . ILE B 1 38  ? 31.288  -16.811 6.747   1.00 31.17  ? 37  ILE I N   1 
ATOM   1792 C CA  . ILE B 1 38  ? 29.903  -16.350 6.839   1.00 32.58  ? 37  ILE I CA  1 
ATOM   1793 C C   . ILE B 1 38  ? 29.825  -14.954 6.233   1.00 35.21  ? 37  ILE I C   1 
ATOM   1794 O O   . ILE B 1 38  ? 30.648  -14.092 6.554   1.00 30.49  ? 37  ILE I O   1 
ATOM   1795 C CB  . ILE B 1 38  ? 29.402  -16.315 8.298   1.00 35.06  ? 37  ILE I CB  1 
ATOM   1796 C CG1 . ILE B 1 38  ? 29.790  -17.589 9.053   1.00 31.06  ? 37  ILE I CG1 1 
ATOM   1797 C CG2 . ILE B 1 38  ? 27.901  -16.050 8.354   1.00 37.92  ? 37  ILE I CG2 1 
ATOM   1798 C CD1 . ILE B 1 38  ? 29.700  -17.451 10.561  1.00 28.36  ? 37  ILE I CD1 1 
ATOM   1799 N N   . ARG B 1 39  ? 28.834  -14.714 5.380   1.00 34.79  ? 38  ARG I N   1 
ATOM   1800 C CA  . ARG B 1 39  ? 28.710  -13.418 4.727   1.00 35.92  ? 38  ARG I CA  1 
ATOM   1801 C C   . ARG B 1 39  ? 27.385  -12.746 5.071   1.00 33.23  ? 38  ARG I C   1 
ATOM   1802 O O   . ARG B 1 39  ? 26.401  -13.398 5.432   1.00 33.61  ? 38  ARG I O   1 
ATOM   1803 C CB  . ARG B 1 39  ? 28.866  -13.546 3.206   1.00 32.84  ? 38  ARG I CB  1 
ATOM   1804 C CG  . ARG B 1 39  ? 27.804  -14.377 2.513   1.00 35.55  ? 38  ARG I CG  1 
ATOM   1805 C CD  . ARG B 1 39  ? 28.047  -14.375 1.013   1.00 36.26  ? 38  ARG I CD  1 
ATOM   1806 N NE  . ARG B 1 39  ? 27.128  -15.245 0.291   1.00 39.89  ? 38  ARG I NE  1 
ATOM   1807 C CZ  . ARG B 1 39  ? 27.168  -15.446 -1.019  1.00 42.45  ? 38  ARG I CZ  1 
ATOM   1808 N NH1 . ARG B 1 39  ? 28.073  -14.854 -1.780  1.00 34.05  ? 38  ARG I NH1 1 
ATOM   1809 N NH2 . ARG B 1 39  ? 26.282  -16.265 -1.577  1.00 33.69  ? 38  ARG I NH2 1 
ATOM   1810 N N   . GLN B 1 40  ? 27.382  -11.417 4.959   1.00 33.01  ? 39  GLN I N   1 
ATOM   1811 C CA  . GLN B 1 40  ? 26.214  -10.588 5.237   1.00 38.60  ? 39  GLN I CA  1 
ATOM   1812 C C   . GLN B 1 40  ? 25.956  -9.707  4.024   1.00 33.40  ? 39  GLN I C   1 
ATOM   1813 O O   . GLN B 1 40  ? 26.825  -8.923  3.628   1.00 33.76  ? 39  GLN I O   1 
ATOM   1814 C CB  . GLN B 1 40  ? 26.425  -9.730  6.491   1.00 33.49  ? 39  GLN I CB  1 
ATOM   1815 C CG  . GLN B 1 40  ? 25.176  -9.009  6.988   1.00 34.73  ? 39  GLN I CG  1 
ATOM   1816 C CD  . GLN B 1 40  ? 25.386  -8.339  8.335   1.00 35.39  ? 39  GLN I CD  1 
ATOM   1817 O OE1 . GLN B 1 40  ? 26.479  -7.866  8.642   1.00 31.01  ? 39  GLN I OE1 1 
ATOM   1818 N NE2 . GLN B 1 40  ? 24.335  -8.301  9.147   1.00 32.29  ? 39  GLN I NE2 1 
ATOM   1819 N N   . PHE B 1 41  ? 24.772  -9.846  3.435   1.00 35.22  ? 40  PHE I N   1 
ATOM   1820 C CA  . PHE B 1 41  ? 24.403  -9.130  2.222   1.00 37.83  ? 40  PHE I CA  1 
ATOM   1821 C C   . PHE B 1 41  ? 23.934  -7.717  2.536   1.00 42.03  ? 40  PHE I C   1 
ATOM   1822 O O   . PHE B 1 41  ? 23.673  -7.373  3.692   1.00 39.28  ? 40  PHE I O   1 
ATOM   1823 C CB  . PHE B 1 41  ? 23.288  -9.880  1.499   1.00 39.92  ? 40  PHE I CB  1 
ATOM   1824 C CG  . PHE B 1 41  ? 23.644  -11.280 1.115   1.00 36.36  ? 40  PHE I CG  1 
ATOM   1825 C CD1 . PHE B 1 41  ? 24.434  -11.525 0.007   1.00 40.86  ? 40  PHE I CD1 1 
ATOM   1826 C CD2 . PHE B 1 41  ? 23.168  -12.354 1.847   1.00 36.31  ? 40  PHE I CD2 1 
ATOM   1827 C CE1 . PHE B 1 41  ? 24.758  -12.815 -0.356  1.00 44.76  ? 40  PHE I CE1 1 
ATOM   1828 C CE2 . PHE B 1 41  ? 23.487  -13.647 1.489   1.00 36.76  ? 40  PHE I CE2 1 
ATOM   1829 C CZ  . PHE B 1 41  ? 24.282  -13.878 0.385   1.00 41.85  ? 40  PHE I CZ  1 
ATOM   1830 N N   . PRO B 1 42  ? 23.843  -6.857  1.518   1.00 40.32  ? 41  PRO I N   1 
ATOM   1831 C CA  . PRO B 1 42  ? 23.069  -5.623  1.676   1.00 40.26  ? 41  PRO I CA  1 
ATOM   1832 C C   . PRO B 1 42  ? 21.669  -5.970  2.159   1.00 41.01  ? 41  PRO I C   1 
ATOM   1833 O O   . PRO B 1 42  ? 21.019  -6.880  1.640   1.00 47.67  ? 41  PRO I O   1 
ATOM   1834 C CB  . PRO B 1 42  ? 23.063  -5.025  0.266   1.00 43.67  ? 41  PRO I CB  1 
ATOM   1835 C CG  . PRO B 1 42  ? 24.338  -5.508  -0.330  1.00 48.70  ? 41  PRO I CG  1 
ATOM   1836 C CD  . PRO B 1 42  ? 24.562  -6.891  0.232   1.00 41.04  ? 41  PRO I CD  1 
ATOM   1837 N N   . GLY B 1 43  ? 21.206  -5.239  3.163   1.00 37.47  ? 42  GLY I N   1 
ATOM   1838 C CA  . GLY B 1 43  ? 19.971  -5.570  3.835   1.00 39.56  ? 42  GLY I CA  1 
ATOM   1839 C C   . GLY B 1 43  ? 20.182  -6.368  5.101   1.00 42.88  ? 42  GLY I C   1 
ATOM   1840 O O   . GLY B 1 43  ? 19.198  -6.760  5.741   1.00 45.12  ? 42  GLY I O   1 
ATOM   1841 N N   . ASN B 1 44  ? 21.440  -6.653  5.449   1.00 38.70  ? 43  ASN I N   1 
ATOM   1842 C CA  . ASN B 1 44  ? 21.860  -7.203  6.735   1.00 42.10  ? 43  ASN I CA  1 
ATOM   1843 C C   . ASN B 1 44  ? 21.498  -8.673  6.929   1.00 41.09  ? 43  ASN I C   1 
ATOM   1844 O O   . ASN B 1 44  ? 21.441  -9.142  8.070   1.00 43.60  ? 43  ASN I O   1 
ATOM   1845 C CB  . ASN B 1 44  ? 21.297  -6.367  7.890   1.00 40.27  ? 43  ASN I CB  1 
ATOM   1846 C CG  . ASN B 1 44  ? 21.806  -4.939  7.872   1.00 43.39  ? 43  ASN I CG  1 
ATOM   1847 O OD1 . ASN B 1 44  ? 22.981  -4.688  7.606   1.00 37.84  ? 43  ASN I OD1 1 
ATOM   1848 N ND2 . ASN B 1 44  ? 20.916  -3.991  8.143   1.00 41.55  ? 43  ASN I ND2 1 
ATOM   1849 N N   . LYS B 1 45  ? 21.261  -9.429  5.859   1.00 33.09  ? 44  LYS I N   1 
ATOM   1850 C CA  . LYS B 1 45  ? 20.972  -10.850 6.014   1.00 40.12  ? 44  LYS I CA  1 
ATOM   1851 C C   . LYS B 1 45  ? 22.267  -11.650 6.103   1.00 39.06  ? 44  LYS I C   1 
ATOM   1852 O O   . LYS B 1 45  ? 23.149  -11.523 5.248   1.00 37.66  ? 44  LYS I O   1 
ATOM   1853 C CB  . LYS B 1 45  ? 20.114  -11.366 4.859   1.00 39.15  ? 44  LYS I CB  1 
ATOM   1854 C CG  . LYS B 1 45  ? 19.786  -12.850 4.974   1.00 42.37  ? 44  LYS I CG  1 
ATOM   1855 C CD  . LYS B 1 45  ? 18.771  -13.298 3.937   1.00 53.92  ? 44  LYS I CD  1 
ATOM   1856 C CE  . LYS B 1 45  ? 19.397  -13.428 2.560   1.00 50.59  ? 44  LYS I CE  1 
ATOM   1857 N NZ  . LYS B 1 45  ? 18.403  -13.870 1.539   1.00 64.60  ? 44  LYS I NZ  1 
ATOM   1858 N N   . LEU B 1 46  ? 22.369  -12.484 7.134   1.00 38.59  ? 45  LEU I N   1 
ATOM   1859 C CA  . LEU B 1 46  ? 23.538  -13.325 7.348   1.00 37.36  ? 45  LEU I CA  1 
ATOM   1860 C C   . LEU B 1 46  ? 23.346  -14.688 6.695   1.00 36.27  ? 45  LEU I C   1 
ATOM   1861 O O   . LEU B 1 46  ? 22.243  -15.242 6.695   1.00 41.48  ? 45  LEU I O   1 
ATOM   1862 C CB  . LEU B 1 46  ? 23.810  -13.494 8.843   1.00 40.12  ? 45  LEU I CB  1 
ATOM   1863 C CG  . LEU B 1 46  ? 24.385  -12.273 9.560   1.00 38.64  ? 45  LEU I CG  1 
ATOM   1864 C CD1 . LEU B 1 46  ? 24.193  -12.394 11.062  1.00 32.58  ? 45  LEU I CD1 1 
ATOM   1865 C CD2 . LEU B 1 46  ? 25.860  -12.116 9.225   1.00 36.25  ? 45  LEU I CD2 1 
ATOM   1866 N N   . GLU B 1 47  ? 24.432  -15.223 6.140   1.00 34.76  ? 46  GLU I N   1 
ATOM   1867 C CA  . GLU B 1 47  ? 24.408  -16.505 5.443   1.00 35.25  ? 46  GLU I CA  1 
ATOM   1868 C C   . GLU B 1 47  ? 25.701  -17.248 5.732   1.00 35.76  ? 46  GLU I C   1 
ATOM   1869 O O   . GLU B 1 47  ? 26.789  -16.743 5.433   1.00 34.81  ? 46  GLU I O   1 
ATOM   1870 C CB  . GLU B 1 47  ? 24.228  -16.309 3.934   1.00 36.08  ? 46  GLU I CB  1 
ATOM   1871 C CG  . GLU B 1 47  ? 24.792  -17.440 3.084   1.00 39.19  ? 46  GLU I CG  1 
ATOM   1872 C CD  . GLU B 1 47  ? 24.286  -17.400 1.658   1.00 41.29  ? 46  GLU I CD  1 
ATOM   1873 O OE1 . GLU B 1 47  ? 23.088  -17.100 1.463   1.00 49.39  ? 46  GLU I OE1 1 
ATOM   1874 O OE2 . GLU B 1 47  ? 25.083  -17.658 0.730   1.00 40.65  ? 46  GLU I OE2 1 
ATOM   1875 N N   . TRP B 1 48  ? 25.584  -18.442 6.309   1.00 33.93  ? 47  TRP I N   1 
ATOM   1876 C CA  . TRP B 1 48  ? 26.745  -19.295 6.513   1.00 35.20  ? 47  TRP I CA  1 
ATOM   1877 C C   . TRP B 1 48  ? 27.165  -19.899 5.179   1.00 34.87  ? 47  TRP I C   1 
ATOM   1878 O O   . TRP B 1 48  ? 26.377  -20.596 4.529   1.00 32.45  ? 47  TRP I O   1 
ATOM   1879 C CB  . TRP B 1 48  ? 26.420  -20.385 7.534   1.00 36.38  ? 47  TRP I CB  1 
ATOM   1880 C CG  . TRP B 1 48  ? 27.477  -21.446 7.687   1.00 38.06  ? 47  TRP I CG  1 
ATOM   1881 C CD1 . TRP B 1 48  ? 28.712  -21.299 8.248   1.00 37.14  ? 47  TRP I CD1 1 
ATOM   1882 C CD2 . TRP B 1 48  ? 27.373  -22.825 7.305   1.00 40.14  ? 47  TRP I CD2 1 
ATOM   1883 N NE1 . TRP B 1 48  ? 29.390  -22.494 8.224   1.00 38.93  ? 47  TRP I NE1 1 
ATOM   1884 C CE2 . TRP B 1 48  ? 28.590  -23.447 7.650   1.00 38.73  ? 47  TRP I CE2 1 
ATOM   1885 C CE3 . TRP B 1 48  ? 26.373  -23.592 6.698   1.00 40.55  ? 47  TRP I CE3 1 
ATOM   1886 C CZ2 . TRP B 1 48  ? 28.833  -24.799 7.409   1.00 41.17  ? 47  TRP I CZ2 1 
ATOM   1887 C CZ3 . TRP B 1 48  ? 26.617  -24.933 6.460   1.00 39.40  ? 47  TRP I CZ3 1 
ATOM   1888 C CH2 . TRP B 1 48  ? 27.836  -25.522 6.815   1.00 41.99  ? 47  TRP I CH2 1 
ATOM   1889 N N   . MET B 1 49  ? 28.410  -19.639 4.775   1.00 36.71  ? 48  MET I N   1 
ATOM   1890 C CA  . MET B 1 49  ? 28.915  -20.142 3.505   1.00 38.34  ? 48  MET I CA  1 
ATOM   1891 C C   . MET B 1 49  ? 29.562  -21.507 3.664   1.00 41.87  ? 48  MET I C   1 
ATOM   1892 O O   . MET B 1 49  ? 29.220  -22.449 2.940   1.00 36.40  ? 48  MET I O   1 
ATOM   1893 C CB  . MET B 1 49  ? 29.945  -19.179 2.905   1.00 36.80  ? 48  MET I CB  1 
ATOM   1894 C CG  . MET B 1 49  ? 29.643  -17.706 3.061   1.00 36.49  ? 48  MET I CG  1 
ATOM   1895 S SD  . MET B 1 49  ? 30.765  -16.706 2.068   1.00 38.37  ? 48  MET I SD  1 
ATOM   1896 C CE  . MET B 1 49  ? 31.044  -17.785 0.666   1.00 40.92  ? 48  MET I CE  1 
ATOM   1897 N N   . GLY B 1 50  ? 30.487  -21.636 4.606   1.00 42.16  ? 49  GLY I N   1 
ATOM   1898 C CA  . GLY B 1 50  ? 31.125  -22.934 4.726   1.00 40.43  ? 49  GLY I CA  1 
ATOM   1899 C C   . GLY B 1 50  ? 32.049  -23.018 5.917   1.00 38.70  ? 49  GLY I C   1 
ATOM   1900 O O   . GLY B 1 50  ? 32.212  -22.065 6.681   1.00 37.85  ? 49  GLY I O   1 
ATOM   1901 N N   . SER B 1 51  ? 32.663  -24.192 6.059   1.00 36.75  ? 50  SER I N   1 
ATOM   1902 C CA  . SER B 1 51  ? 33.549  -24.463 7.177   1.00 40.02  ? 50  SER I CA  1 
ATOM   1903 C C   . SER B 1 51  ? 34.622  -25.459 6.765   1.00 41.41  ? 50  SER I C   1 
ATOM   1904 O O   . SER B 1 51  ? 34.368  -26.391 5.992   1.00 44.06  ? 50  SER I O   1 
ATOM   1905 C CB  . SER B 1 51  ? 32.783  -25.019 8.383   1.00 38.39  ? 50  SER I CB  1 
ATOM   1906 O OG  . SER B 1 51  ? 31.639  -24.239 8.674   1.00 44.02  ? 50  SER I OG  1 
ATOM   1907 N N   . ILE B 1 52  ? 35.815  -25.264 7.323   1.00 39.31  ? 51  ILE I N   1 
ATOM   1908 C CA  . ILE B 1 52  ? 36.868  -26.269 7.302   1.00 41.18  ? 51  ILE I CA  1 
ATOM   1909 C C   . ILE B 1 52  ? 37.142  -26.640 8.751   1.00 43.33  ? 51  ILE I C   1 
ATOM   1910 O O   . ILE B 1 52  ? 37.221  -25.769 9.623   1.00 39.42  ? 51  ILE I O   1 
ATOM   1911 C CB  . ILE B 1 52  ? 38.147  -25.776 6.586   1.00 34.43  ? 51  ILE I CB  1 
ATOM   1912 C CG1 . ILE B 1 52  ? 39.156  -26.920 6.439   1.00 44.62  ? 51  ILE I CG1 1 
ATOM   1913 C CG2 . ILE B 1 52  ? 38.761  -24.568 7.293   1.00 39.79  ? 51  ILE I CG2 1 
ATOM   1914 C CD1 . ILE B 1 52  ? 40.382  -26.565 5.630   1.00 46.98  ? 51  ILE I CD1 1 
ATOM   1915 N N   . ASN B 1 53  ? 37.269  -27.934 9.008   1.00 44.92  ? 52  ASN I N   1 
ATOM   1916 C CA  . ASN B 1 53  ? 37.383  -28.414 10.373  1.00 44.14  ? 52  ASN I CA  1 
ATOM   1917 C C   . ASN B 1 53  ? 38.838  -28.387 10.839  1.00 44.34  ? 52  ASN I C   1 
ATOM   1918 O O   . ASN B 1 53  ? 39.764  -28.123 10.068  1.00 41.34  ? 52  ASN I O   1 
ATOM   1919 C CB  . ASN B 1 53  ? 36.780  -29.816 10.478  1.00 44.31  ? 52  ASN I CB  1 
ATOM   1920 C CG  . ASN B 1 53  ? 36.600  -30.273 11.910  1.00 45.99  ? 52  ASN I CG  1 
ATOM   1921 O OD1 . ASN B 1 53  ? 36.328  -29.466 12.799  1.00 45.05  ? 52  ASN I OD1 1 
ATOM   1922 N ND2 . ASN B 1 53  ? 36.738  -31.571 12.141  1.00 45.85  ? 52  ASN I ND2 1 
ATOM   1923 N N   . TYR B 1 54  ? 39.032  -28.657 12.134  1.00 42.03  ? 53  TYR I N   1 
ATOM   1924 C CA  . TYR B 1 54  ? 40.382  -28.713 12.683  1.00 38.93  ? 53  TYR I CA  1 
ATOM   1925 C C   . TYR B 1 54  ? 41.193  -29.844 12.065  1.00 35.58  ? 53  TYR I C   1 
ATOM   1926 O O   . TYR B 1 54  ? 42.421  -29.744 11.966  1.00 35.00  ? 53  TYR I O   1 
ATOM   1927 C CB  . TYR B 1 54  ? 40.327  -28.872 14.204  1.00 44.46  ? 53  TYR I CB  1 
ATOM   1928 C CG  . TYR B 1 54  ? 39.809  -30.217 14.671  1.00 41.31  ? 53  TYR I CG  1 
ATOM   1929 C CD1 . TYR B 1 54  ? 40.679  -31.277 14.902  1.00 41.52  ? 53  TYR I CD1 1 
ATOM   1930 C CD2 . TYR B 1 54  ? 38.453  -30.426 14.886  1.00 42.97  ? 53  TYR I CD2 1 
ATOM   1931 C CE1 . TYR B 1 54  ? 40.213  -32.505 15.326  1.00 42.99  ? 53  TYR I CE1 1 
ATOM   1932 C CE2 . TYR B 1 54  ? 37.978  -31.652 15.313  1.00 47.88  ? 53  TYR I CE2 1 
ATOM   1933 C CZ  . TYR B 1 54  ? 38.862  -32.687 15.531  1.00 46.73  ? 53  TYR I CZ  1 
ATOM   1934 O OH  . TYR B 1 54  ? 38.399  -33.911 15.955  1.00 48.09  ? 53  TYR I OH  1 
ATOM   1935 N N   . ASP B 1 55  ? 40.532  -30.922 11.649  1.00 38.15  ? 54  ASP I N   1 
ATOM   1936 C CA  . ASP B 1 55  ? 41.210  -32.065 11.055  1.00 45.98  ? 54  ASP I CA  1 
ATOM   1937 C C   . ASP B 1 55  ? 41.347  -31.954 9.542   1.00 43.13  ? 54  ASP I C   1 
ATOM   1938 O O   . ASP B 1 55  ? 41.923  -32.853 8.920   1.00 45.66  ? 54  ASP I O   1 
ATOM   1939 C CB  . ASP B 1 55  ? 40.478  -33.363 11.417  1.00 40.74  ? 54  ASP I CB  1 
ATOM   1940 C CG  . ASP B 1 55  ? 39.031  -33.374 10.953  1.00 46.80  ? 54  ASP I CG  1 
ATOM   1941 O OD1 . ASP B 1 55  ? 38.577  -32.371 10.367  1.00 48.89  ? 54  ASP I OD1 1 
ATOM   1942 O OD2 . ASP B 1 55  ? 38.345  -34.392 11.177  1.00 45.99  ? 54  ASP I OD2 1 
ATOM   1943 N N   . GLY B 1 56  ? 40.832  -30.886 8.937   1.00 43.55  ? 55  GLY I N   1 
ATOM   1944 C CA  . GLY B 1 56  ? 40.966  -30.668 7.513   1.00 40.73  ? 55  GLY I CA  1 
ATOM   1945 C C   . GLY B 1 56  ? 39.762  -31.045 6.678   1.00 42.02  ? 55  GLY I C   1 
ATOM   1946 O O   . GLY B 1 56  ? 39.822  -30.918 5.449   1.00 48.04  ? 55  GLY I O   1 
ATOM   1947 N N   . SER B 1 57  ? 38.678  -31.507 7.295   1.00 42.20  ? 56  SER I N   1 
ATOM   1948 C CA  . SER B 1 57  ? 37.474  -31.825 6.545   1.00 42.83  ? 56  SER I CA  1 
ATOM   1949 C C   . SER B 1 57  ? 36.667  -30.558 6.275   1.00 45.46  ? 56  SER I C   1 
ATOM   1950 O O   . SER B 1 57  ? 36.812  -29.539 6.954   1.00 40.96  ? 56  SER I O   1 
ATOM   1951 C CB  . SER B 1 57  ? 36.622  -32.850 7.297   1.00 42.68  ? 56  SER I CB  1 
ATOM   1952 O OG  . SER B 1 57  ? 36.256  -32.375 8.580   1.00 46.32  ? 56  SER I OG  1 
ATOM   1953 N N   . ASN B 1 58  ? 35.807  -30.634 5.263   1.00 43.79  ? 57  ASN I N   1 
ATOM   1954 C CA  . ASN B 1 58  ? 35.023  -29.494 4.813   1.00 44.68  ? 57  ASN I CA  1 
ATOM   1955 C C   . ASN B 1 58  ? 33.534  -29.782 4.929   1.00 41.61  ? 57  ASN I C   1 
ATOM   1956 O O   . ASN B 1 58  ? 33.096  -30.933 4.831   1.00 39.79  ? 57  ASN I O   1 
ATOM   1957 C CB  . ASN B 1 58  ? 35.347  -29.130 3.357   1.00 41.46  ? 57  ASN I CB  1 
ATOM   1958 C CG  . ASN B 1 58  ? 36.684  -28.439 3.211   1.00 47.75  ? 57  ASN I CG  1 
ATOM   1959 O OD1 . ASN B 1 58  ? 37.521  -28.846 2.406   1.00 53.86  ? 57  ASN I OD1 1 
ATOM   1960 N ND2 . ASN B 1 58  ? 36.890  -27.384 3.987   1.00 43.29  ? 57  ASN I ND2 1 
ATOM   1961 N N   . ILE B 1 59  ? 32.760  -28.718 5.140   1.00 43.01  ? 58  ILE I N   1 
ATOM   1962 C CA  . ILE B 1 59  ? 31.311  -28.755 4.967   1.00 42.88  ? 58  ILE I CA  1 
ATOM   1963 C C   . ILE B 1 59  ? 30.879  -27.444 4.328   1.00 41.79  ? 58  ILE I C   1 
ATOM   1964 O O   . ILE B 1 59  ? 31.466  -26.389 4.592   1.00 40.94  ? 58  ILE I O   1 
ATOM   1965 C CB  . ILE B 1 59  ? 30.558  -28.999 6.293   1.00 46.91  ? 58  ILE I CB  1 
ATOM   1966 C CG1 . ILE B 1 59  ? 31.224  -28.264 7.453   1.00 42.93  ? 58  ILE I CG1 1 
ATOM   1967 C CG2 . ILE B 1 59  ? 30.436  -30.493 6.578   1.00 47.68  ? 58  ILE I CG2 1 
ATOM   1968 C CD1 . ILE B 1 59  ? 30.426  -28.335 8.738   1.00 44.11  ? 58  ILE I CD1 1 
ATOM   1969 N N   . TYR B 1 60  ? 29.857  -27.509 3.478   1.00 37.03  ? 59  TYR I N   1 
ATOM   1970 C CA  . TYR B 1 60  ? 29.438  -26.358 2.693   1.00 44.38  ? 59  TYR I CA  1 
ATOM   1971 C C   . TYR B 1 60  ? 27.925  -26.197 2.725   1.00 42.27  ? 59  TYR I C   1 
ATOM   1972 O O   . TYR B 1 60  ? 27.179  -27.169 2.877   1.00 43.98  ? 59  TYR I O   1 
ATOM   1973 C CB  . TYR B 1 60  ? 29.904  -26.474 1.230   1.00 41.08  ? 59  TYR I CB  1 
ATOM   1974 C CG  . TYR B 1 60  ? 31.401  -26.599 1.055   1.00 33.71  ? 59  TYR I CG  1 
ATOM   1975 C CD1 . TYR B 1 60  ? 32.263  -25.629 1.551   1.00 39.94  ? 59  TYR I CD1 1 
ATOM   1976 C CD2 . TYR B 1 60  ? 31.950  -27.680 0.377   1.00 36.73  ? 59  TYR I CD2 1 
ATOM   1977 C CE1 . TYR B 1 60  ? 33.632  -25.738 1.386   1.00 40.29  ? 59  TYR I CE1 1 
ATOM   1978 C CE2 . TYR B 1 60  ? 33.317  -27.797 0.207   1.00 32.38  ? 59  TYR I CE2 1 
ATOM   1979 C CZ  . TYR B 1 60  ? 34.153  -26.823 0.714   1.00 33.77  ? 59  TYR I CZ  1 
ATOM   1980 O OH  . TYR B 1 60  ? 35.515  -26.935 0.547   1.00 38.68  ? 59  TYR I OH  1 
ATOM   1981 N N   . ASN B 1 61  ? 27.490  -24.949 2.585   1.00 45.52  ? 60  ASN I N   1 
ATOM   1982 C CA  . ASN B 1 61  ? 26.090  -24.653 2.333   1.00 53.08  ? 60  ASN I CA  1 
ATOM   1983 C C   . ASN B 1 61  ? 25.683  -25.247 0.987   1.00 45.50  ? 60  ASN I C   1 
ATOM   1984 O O   . ASN B 1 61  ? 26.371  -25.017 -0.018  1.00 44.54  ? 60  ASN I O   1 
ATOM   1985 C CB  . ASN B 1 61  ? 25.885  -23.135 2.347   1.00 46.18  ? 60  ASN I CB  1 
ATOM   1986 C CG  . ASN B 1 61  ? 24.429  -22.723 2.532   1.00 48.59  ? 60  ASN I CG  1 
ATOM   1987 O OD1 . ASN B 1 61  ? 23.516  -23.339 1.985   1.00 51.05  ? 60  ASN I OD1 1 
ATOM   1988 N ND2 . ASN B 1 61  ? 24.211  -21.672 3.313   1.00 41.75  ? 60  ASN I ND2 1 
ATOM   1989 N N   . PRO B 1 62  ? 24.602  -26.030 0.921   1.00 46.92  ? 61  PRO I N   1 
ATOM   1990 C CA  . PRO B 1 62  ? 24.164  -26.558 -0.386  1.00 52.16  ? 61  PRO I CA  1 
ATOM   1991 C C   . PRO B 1 62  ? 23.886  -25.477 -1.416  1.00 54.21  ? 61  PRO I C   1 
ATOM   1992 O O   . PRO B 1 62  ? 24.082  -25.711 -2.615  1.00 55.23  ? 61  PRO I O   1 
ATOM   1993 C CB  . PRO B 1 62  ? 22.895  -27.357 -0.041  1.00 49.29  ? 61  PRO I CB  1 
ATOM   1994 C CG  . PRO B 1 62  ? 22.436  -26.799 1.281   1.00 52.94  ? 61  PRO I CG  1 
ATOM   1995 C CD  . PRO B 1 62  ? 23.691  -26.415 2.011   1.00 53.05  ? 61  PRO I CD  1 
ATOM   1996 N N   . SER B 1 63  ? 23.449  -24.293 -0.980  1.00 52.82  ? 62  SER I N   1 
ATOM   1997 C CA  . SER B 1 63  ? 23.216  -23.183 -1.898  1.00 47.42  ? 62  SER I CA  1 
ATOM   1998 C C   . SER B 1 63  ? 24.488  -22.742 -2.610  1.00 50.76  ? 62  SER I C   1 
ATOM   1999 O O   . SER B 1 63  ? 24.405  -22.036 -3.621  1.00 64.15  ? 62  SER I O   1 
ATOM   2000 C CB  . SER B 1 63  ? 22.602  -22.001 -1.148  1.00 46.29  ? 62  SER I CB  1 
ATOM   2001 O OG  . SER B 1 63  ? 23.577  -21.324 -0.378  1.00 46.17  ? 62  SER I OG  1 
ATOM   2002 N N   . LEU B 1 64  ? 25.660  -23.142 -2.111  1.00 51.18  ? 63  LEU I N   1 
ATOM   2003 C CA  . LEU B 1 64  ? 26.929  -22.696 -2.666  1.00 49.57  ? 63  LEU I CA  1 
ATOM   2004 C C   . LEU B 1 64  ? 27.877  -23.852 -2.957  1.00 55.49  ? 63  LEU I C   1 
ATOM   2005 O O   . LEU B 1 64  ? 29.020  -23.608 -3.353  1.00 57.84  ? 63  LEU I O   1 
ATOM   2006 C CB  . LEU B 1 64  ? 27.606  -21.715 -1.701  1.00 51.43  ? 63  LEU I CB  1 
ATOM   2007 C CG  . LEU B 1 64  ? 26.886  -20.407 -1.376  1.00 57.20  ? 63  LEU I CG  1 
ATOM   2008 C CD1 . LEU B 1 64  ? 27.633  -19.651 -0.287  1.00 46.89  ? 63  LEU I CD1 1 
ATOM   2009 C CD2 . LEU B 1 64  ? 26.741  -19.551 -2.621  1.00 47.71  ? 63  LEU I CD2 1 
ATOM   2010 N N   . LYS B 1 65  ? 27.421  -25.100 -2.811  1.00 56.93  ? 64  LYS I N   1 
ATOM   2011 C CA  . LYS B 1 65  ? 28.313  -26.252 -2.915  1.00 59.68  ? 64  LYS I CA  1 
ATOM   2012 C C   . LYS B 1 65  ? 28.943  -26.376 -4.297  1.00 63.16  ? 64  LYS I C   1 
ATOM   2013 O O   . LYS B 1 65  ? 30.017  -26.976 -4.428  1.00 59.22  ? 64  LYS I O   1 
ATOM   2014 C CB  . LYS B 1 65  ? 27.543  -27.532 -2.572  1.00 61.80  ? 64  LYS I CB  1 
ATOM   2015 C CG  . LYS B 1 65  ? 28.366  -28.812 -2.626  1.00 63.37  ? 64  LYS I CG  1 
ATOM   2016 C CD  . LYS B 1 65  ? 27.553  -30.018 -2.183  1.00 68.62  ? 64  LYS I CD  1 
ATOM   2017 C CE  . LYS B 1 65  ? 27.237  -29.961 -0.700  1.00 70.03  ? 64  LYS I CE  1 
ATOM   2018 N NZ  . LYS B 1 65  ? 26.545  -31.194 -0.236  1.00 70.39  ? 64  LYS I NZ  1 
ATOM   2019 N N   . ASP B 1 66  ? 28.319  -25.798 -5.322  1.00 61.27  ? 65  ASP I N   1 
ATOM   2020 C CA  . ASP B 1 66  ? 28.789  -25.964 -6.690  1.00 61.33  ? 65  ASP I CA  1 
ATOM   2021 C C   . ASP B 1 66  ? 30.000  -25.102 -7.026  1.00 61.24  ? 65  ASP I C   1 
ATOM   2022 O O   . ASP B 1 66  ? 30.659  -25.360 -8.039  1.00 67.24  ? 65  ASP I O   1 
ATOM   2023 C CB  . ASP B 1 66  ? 27.655  -25.639 -7.664  1.00 71.43  ? 65  ASP I CB  1 
ATOM   2024 C CG  . ASP B 1 66  ? 26.761  -24.520 -7.159  1.00 73.12  ? 65  ASP I CG  1 
ATOM   2025 O OD1 . ASP B 1 66  ? 25.543  -24.561 -7.424  1.00 75.74  ? 65  ASP I OD1 1 
ATOM   2026 O OD2 . ASP B 1 66  ? 27.272  -23.613 -6.472  1.00 68.52  ? 65  ASP I OD2 1 
ATOM   2027 N N   . ARG B 1 67  ? 30.314  -24.090 -6.209  1.00 57.76  ? 66  ARG I N   1 
ATOM   2028 C CA  . ARG B 1 67  ? 31.382  -23.168 -6.575  1.00 54.04  ? 66  ARG I CA  1 
ATOM   2029 C C   . ARG B 1 67  ? 32.218  -22.683 -5.391  1.00 49.59  ? 66  ARG I C   1 
ATOM   2030 O O   . ARG B 1 67  ? 32.900  -21.658 -5.514  1.00 51.89  ? 66  ARG I O   1 
ATOM   2031 C CB  . ARG B 1 67  ? 30.778  -21.969 -7.317  1.00 52.04  ? 66  ARG I CB  1 
ATOM   2032 C CG  . ARG B 1 67  ? 29.525  -21.423 -6.647  1.00 57.16  ? 66  ARG I CG  1 
ATOM   2033 C CD  . ARG B 1 67  ? 28.937  -20.237 -7.391  1.00 46.95  ? 66  ARG I CD  1 
ATOM   2034 N NE  . ARG B 1 67  ? 27.924  -19.549 -6.600  1.00 46.82  ? 66  ARG I NE  1 
ATOM   2035 C CZ  . ARG B 1 67  ? 28.014  -18.291 -6.190  1.00 42.89  ? 66  ARG I CZ  1 
ATOM   2036 N NH1 . ARG B 1 67  ? 29.061  -17.540 -6.487  1.00 42.48  ? 66  ARG I NH1 1 
ATOM   2037 N NH2 . ARG B 1 67  ? 27.026  -17.773 -5.466  1.00 36.25  ? 66  ARG I NH2 1 
ATOM   2038 N N   . ILE B 1 68  ? 32.202  -23.381 -4.255  1.00 47.87  ? 67  ILE I N   1 
ATOM   2039 C CA  . ILE B 1 68  ? 32.922  -22.930 -3.069  1.00 46.62  ? 67  ILE I CA  1 
ATOM   2040 C C   . ILE B 1 68  ? 34.054  -23.906 -2.768  1.00 44.69  ? 67  ILE I C   1 
ATOM   2041 O O   . ILE B 1 68  ? 33.948  -25.115 -3.012  1.00 51.38  ? 67  ILE I O   1 
ATOM   2042 C CB  . ILE B 1 68  ? 31.982  -22.776 -1.852  1.00 48.53  ? 67  ILE I CB  1 
ATOM   2043 C CG1 . ILE B 1 68  ? 32.733  -22.229 -0.636  1.00 44.95  ? 67  ILE I CG1 1 
ATOM   2044 C CG2 . ILE B 1 68  ? 31.377  -24.103 -1.474  1.00 50.92  ? 67  ILE I CG2 1 
ATOM   2045 C CD1 . ILE B 1 68  ? 31.902  -21.282 0.201   1.00 49.15  ? 67  ILE I CD1 1 
ATOM   2046 N N   . SER B 1 69  ? 35.154  -23.366 -2.245  1.00 43.36  ? 68  SER I N   1 
ATOM   2047 C CA  . SER B 1 69  ? 36.296  -24.174 -1.829  1.00 43.37  ? 68  SER I CA  1 
ATOM   2048 C C   . SER B 1 69  ? 36.976  -23.491 -0.653  1.00 42.52  ? 68  SER I C   1 
ATOM   2049 O O   . SER B 1 69  ? 37.482  -22.376 -0.795  1.00 37.80  ? 68  SER I O   1 
ATOM   2050 C CB  . SER B 1 69  ? 37.282  -24.363 -2.982  1.00 43.61  ? 68  SER I CB  1 
ATOM   2051 O OG  . SER B 1 69  ? 38.595  -24.581 -2.496  1.00 53.36  ? 68  SER I OG  1 
ATOM   2052 N N   . ILE B 1 70  ? 37.000  -24.153 0.500   1.00 40.83  ? 69  ILE I N   1 
ATOM   2053 C CA  . ILE B 1 70  ? 37.656  -23.625 1.692   1.00 34.58  ? 69  ILE I CA  1 
ATOM   2054 C C   . ILE B 1 70  ? 38.867  -24.496 1.992   1.00 39.08  ? 69  ILE I C   1 
ATOM   2055 O O   . ILE B 1 70  ? 38.727  -25.689 2.287   1.00 44.70  ? 69  ILE I O   1 
ATOM   2056 C CB  . ILE B 1 70  ? 36.700  -23.568 2.891   1.00 38.57  ? 69  ILE I CB  1 
ATOM   2057 C CG1 . ILE B 1 70  ? 35.502  -22.678 2.559   1.00 36.28  ? 69  ILE I CG1 1 
ATOM   2058 C CG2 . ILE B 1 70  ? 37.421  -23.057 4.128   1.00 37.93  ? 69  ILE I CG2 1 
ATOM   2059 C CD1 . ILE B 1 70  ? 34.513  -22.562 3.678   1.00 38.11  ? 69  ILE I CD1 1 
ATOM   2060 N N   . THR B 1 71  ? 40.051  -23.899 1.920   1.00 37.13  ? 70  THR I N   1 
ATOM   2061 C CA  . THR B 1 71  ? 41.303  -24.614 2.145   1.00 36.26  ? 70  THR I CA  1 
ATOM   2062 C C   . THR B 1 71  ? 42.033  -24.005 3.338   1.00 38.24  ? 70  THR I C   1 
ATOM   2063 O O   . THR B 1 71  ? 41.537  -23.087 3.989   1.00 38.22  ? 70  THR I O   1 
ATOM   2064 C CB  . THR B 1 71  ? 42.180  -24.589 0.888   1.00 39.59  ? 70  THR I CB  1 
ATOM   2065 O OG1 . THR B 1 71  ? 42.506  -23.234 0.555   1.00 44.98  ? 70  THR I OG1 1 
ATOM   2066 C CG2 . THR B 1 71  ? 41.449  -25.234 -0.282  1.00 42.09  ? 70  THR I CG2 1 
ATOM   2067 N N   . ARG B 1 72  ? 43.227  -24.519 3.626   1.00 39.34  ? 71  ARG I N   1 
ATOM   2068 C CA  . ARG B 1 72  ? 43.964  -24.037 4.787   1.00 41.73  ? 71  ARG I CA  1 
ATOM   2069 C C   . ARG B 1 72  ? 45.452  -24.282 4.593   1.00 41.02  ? 71  ARG I C   1 
ATOM   2070 O O   . ARG B 1 72  ? 45.869  -25.121 3.790   1.00 44.39  ? 71  ARG I O   1 
ATOM   2071 C CB  . ARG B 1 72  ? 43.513  -24.704 6.090   1.00 41.75  ? 71  ARG I CB  1 
ATOM   2072 C CG  . ARG B 1 72  ? 43.990  -26.135 6.247   1.00 43.41  ? 71  ARG I CG  1 
ATOM   2073 C CD  . ARG B 1 72  ? 43.566  -26.711 7.584   1.00 43.90  ? 71  ARG I CD  1 
ATOM   2074 N NE  . ARG B 1 72  ? 43.989  -28.097 7.732   1.00 50.73  ? 71  ARG I NE  1 
ATOM   2075 C CZ  . ARG B 1 72  ? 43.812  -28.820 8.829   1.00 47.37  ? 71  ARG I CZ  1 
ATOM   2076 N NH1 . ARG B 1 72  ? 43.214  -28.320 9.898   1.00 42.49  ? 71  ARG I NH1 1 
ATOM   2077 N NH2 . ARG B 1 72  ? 44.251  -30.075 8.856   1.00 47.48  ? 71  ARG I NH2 1 
ATOM   2078 N N   . ASP B 1 73  ? 46.242  -23.522 5.347   1.00 44.54  ? 72  ASP I N   1 
ATOM   2079 C CA  . ASP B 1 73  ? 47.685  -23.694 5.433   1.00 51.52  ? 72  ASP I CA  1 
ATOM   2080 C C   . ASP B 1 73  ? 48.045  -23.589 6.905   1.00 50.01  ? 72  ASP I C   1 
ATOM   2081 O O   . ASP B 1 73  ? 47.834  -22.540 7.523   1.00 54.32  ? 72  ASP I O   1 
ATOM   2082 C CB  . ASP B 1 73  ? 48.425  -22.636 4.604   1.00 52.04  ? 72  ASP I CB  1 
ATOM   2083 C CG  . ASP B 1 73  ? 49.935  -22.707 4.765   1.00 56.91  ? 72  ASP I CG  1 
ATOM   2084 O OD1 . ASP B 1 73  ? 50.448  -22.297 5.828   1.00 61.88  ? 72  ASP I OD1 1 
ATOM   2085 O OD2 . ASP B 1 73  ? 50.610  -23.175 3.825   1.00 66.70  ? 72  ASP I OD2 1 
ATOM   2086 N N   . THR B 1 74  ? 48.578  -24.676 7.466   1.00 49.70  ? 73  THR I N   1 
ATOM   2087 C CA  . THR B 1 74  ? 48.826  -24.746 8.899   1.00 49.55  ? 73  THR I CA  1 
ATOM   2088 C C   . THR B 1 74  ? 50.190  -24.204 9.294   1.00 49.47  ? 73  THR I C   1 
ATOM   2089 O O   . THR B 1 74  ? 50.411  -23.928 10.480  1.00 53.23  ? 73  THR I O   1 
ATOM   2090 C CB  . THR B 1 74  ? 48.693  -26.191 9.392   1.00 47.07  ? 73  THR I CB  1 
ATOM   2091 O OG1 . THR B 1 74  ? 49.752  -26.984 8.841   1.00 51.75  ? 73  THR I OG1 1 
ATOM   2092 C CG2 . THR B 1 74  ? 47.354  -26.777 8.968   1.00 42.23  ? 73  THR I CG2 1 
ATOM   2093 N N   . SER B 1 75  ? 51.106  -24.047 8.337   1.00 50.47  ? 74  SER I N   1 
ATOM   2094 C CA  . SER B 1 75  ? 52.405  -23.467 8.654   1.00 53.92  ? 74  SER I CA  1 
ATOM   2095 C C   . SER B 1 75  ? 52.257  -22.000 9.030   1.00 54.56  ? 74  SER I C   1 
ATOM   2096 O O   . SER B 1 75  ? 52.961  -21.502 9.917   1.00 54.00  ? 74  SER I O   1 
ATOM   2097 C CB  . SER B 1 75  ? 53.366  -23.633 7.477   1.00 55.31  ? 74  SER I CB  1 
ATOM   2098 O OG  . SER B 1 75  ? 53.356  -22.488 6.642   1.00 63.72  ? 74  SER I OG  1 
ATOM   2099 N N   . LYS B 1 76  ? 51.343  -21.294 8.367   1.00 51.85  ? 75  LYS I N   1 
ATOM   2100 C CA  . LYS B 1 76  ? 51.059  -19.898 8.658   1.00 55.41  ? 75  LYS I CA  1 
ATOM   2101 C C   . LYS B 1 76  ? 49.770  -19.714 9.448   1.00 49.92  ? 75  LYS I C   1 
ATOM   2102 O O   . LYS B 1 76  ? 49.387  -18.572 9.721   1.00 47.26  ? 75  LYS I O   1 
ATOM   2103 C CB  . LYS B 1 76  ? 50.972  -19.099 7.353   1.00 55.42  ? 75  LYS I CB  1 
ATOM   2104 C CG  . LYS B 1 76  ? 52.216  -19.175 6.484   1.00 58.56  ? 75  LYS I CG  1 
ATOM   2105 C CD  . LYS B 1 76  ? 52.056  -18.345 5.220   1.00 60.15  ? 75  LYS I CD  1 
ATOM   2106 C CE  . LYS B 1 76  ? 53.407  -17.990 4.623   1.00 67.07  ? 75  LYS I CE  1 
ATOM   2107 N NZ  . LYS B 1 76  ? 54.207  -19.201 4.297   1.00 68.06  ? 75  LYS I NZ  1 
ATOM   2108 N N   . ASN B 1 77  ? 49.098  -20.807 9.816   1.00 50.53  ? 76  ASN I N   1 
ATOM   2109 C CA  . ASN B 1 77  ? 47.870  -20.774 10.612  1.00 46.87  ? 76  ASN I CA  1 
ATOM   2110 C C   . ASN B 1 77  ? 46.815  -19.886 9.948   1.00 47.42  ? 76  ASN I C   1 
ATOM   2111 O O   . ASN B 1 77  ? 46.291  -18.940 10.539  1.00 43.34  ? 76  ASN I O   1 
ATOM   2112 C CB  . ASN B 1 77  ? 48.162  -20.317 12.046  1.00 42.89  ? 76  ASN I CB  1 
ATOM   2113 C CG  . ASN B 1 77  ? 47.083  -20.741 13.025  1.00 47.27  ? 76  ASN I CG  1 
ATOM   2114 O OD1 . ASN B 1 77  ? 46.409  -21.751 12.824  1.00 46.22  ? 76  ASN I OD1 1 
ATOM   2115 N ND2 . ASN B 1 77  ? 46.917  -19.971 14.093  1.00 44.54  ? 76  ASN I ND2 1 
ATOM   2116 N N   . GLN B 1 78  ? 46.508  -20.216 8.696   1.00 47.85  ? 77  GLN I N   1 
ATOM   2117 C CA  . GLN B 1 78  ? 45.574  -19.444 7.892   1.00 39.65  ? 77  GLN I CA  1 
ATOM   2118 C C   . GLN B 1 78  ? 44.594  -20.382 7.208   1.00 42.22  ? 77  GLN I C   1 
ATOM   2119 O O   . GLN B 1 78  ? 44.914  -21.540 6.933   1.00 47.35  ? 77  GLN I O   1 
ATOM   2120 C CB  . GLN B 1 78  ? 46.301  -18.610 6.828   1.00 42.65  ? 77  GLN I CB  1 
ATOM   2121 C CG  . GLN B 1 78  ? 47.182  -17.505 7.379   1.00 44.76  ? 77  GLN I CG  1 
ATOM   2122 C CD  . GLN B 1 78  ? 48.039  -16.864 6.307   1.00 48.53  ? 77  GLN I CD  1 
ATOM   2123 O OE1 . GLN B 1 78  ? 48.242  -17.436 5.236   1.00 49.67  ? 77  GLN I OE1 1 
ATOM   2124 N NE2 . GLN B 1 78  ? 48.546  -15.671 6.589   1.00 49.68  ? 77  GLN I NE2 1 
ATOM   2125 N N   . PHE B 1 79  ? 43.387  -19.887 6.952   1.00 37.45  ? 78  PHE I N   1 
ATOM   2126 C CA  . PHE B 1 79  ? 42.469  -20.624 6.091   1.00 35.50  ? 78  PHE I CA  1 
ATOM   2127 C C   . PHE B 1 79  ? 41.814  -19.688 5.085   1.00 39.11  ? 78  PHE I C   1 
ATOM   2128 O O   . PHE B 1 79  ? 41.575  -18.511 5.364   1.00 40.78  ? 78  PHE I O   1 
ATOM   2129 C CB  . PHE B 1 79  ? 41.419  -21.421 6.905   1.00 33.30  ? 78  PHE I CB  1 
ATOM   2130 C CG  . PHE B 1 79  ? 40.405  -20.579 7.623   1.00 40.34  ? 78  PHE I CG  1 
ATOM   2131 C CD1 . PHE B 1 79  ? 40.743  -19.907 8.785   1.00 40.30  ? 78  PHE I CD1 1 
ATOM   2132 C CD2 . PHE B 1 79  ? 39.101  -20.500 7.165   1.00 35.51  ? 78  PHE I CD2 1 
ATOM   2133 C CE1 . PHE B 1 79  ? 39.807  -19.149 9.461   1.00 36.06  ? 78  PHE I CE1 1 
ATOM   2134 C CE2 . PHE B 1 79  ? 38.159  -19.742 7.836   1.00 37.14  ? 78  PHE I CE2 1 
ATOM   2135 C CZ  . PHE B 1 79  ? 38.514  -19.067 8.986   1.00 37.50  ? 78  PHE I CZ  1 
ATOM   2136 N N   . PHE B 1 80  ? 41.519  -20.232 3.905   1.00 38.72  ? 79  PHE I N   1 
ATOM   2137 C CA  . PHE B 1 80  ? 41.198  -19.433 2.734   1.00 40.48  ? 79  PHE I CA  1 
ATOM   2138 C C   . PHE B 1 80  ? 39.856  -19.844 2.154   1.00 38.58  ? 79  PHE I C   1 
ATOM   2139 O O   . PHE B 1 80  ? 39.463  -21.015 2.203   1.00 36.75  ? 79  PHE I O   1 
ATOM   2140 C CB  . PHE B 1 80  ? 42.257  -19.577 1.627   1.00 35.72  ? 79  PHE I CB  1 
ATOM   2141 C CG  . PHE B 1 80  ? 43.667  -19.612 2.129   1.00 33.80  ? 79  PHE I CG  1 
ATOM   2142 C CD1 . PHE B 1 80  ? 44.372  -18.440 2.334   1.00 38.36  ? 79  PHE I CD1 1 
ATOM   2143 C CD2 . PHE B 1 80  ? 44.296  -20.820 2.380   1.00 37.89  ? 79  PHE I CD2 1 
ATOM   2144 C CE1 . PHE B 1 80  ? 45.674  -18.470 2.791   1.00 39.76  ? 79  PHE I CE1 1 
ATOM   2145 C CE2 . PHE B 1 80  ? 45.597  -20.856 2.838   1.00 44.43  ? 79  PHE I CE2 1 
ATOM   2146 C CZ  . PHE B 1 80  ? 46.287  -19.680 3.042   1.00 41.81  ? 79  PHE I CZ  1 
ATOM   2147 N N   . LEU B 1 81  ? 39.196  -18.859 1.553   1.00 35.37  ? 80  LEU I N   1 
ATOM   2148 C CA  . LEU B 1 81  ? 37.925  -19.010 0.865   1.00 39.46  ? 80  LEU I CA  1 
ATOM   2149 C C   . LEU B 1 81  ? 38.111  -18.716 -0.616  1.00 41.82  ? 80  LEU I C   1 
ATOM   2150 O O   . LEU B 1 81  ? 38.750  -17.723 -0.989  1.00 40.87  ? 80  LEU I O   1 
ATOM   2151 C CB  . LEU B 1 81  ? 36.869  -18.061 1.448   1.00 37.11  ? 80  LEU I CB  1 
ATOM   2152 C CG  . LEU B 1 81  ? 35.551  -17.927 0.684   1.00 39.28  ? 80  LEU I CG  1 
ATOM   2153 C CD1 . LEU B 1 81  ? 34.647  -19.104 0.987   1.00 39.23  ? 80  LEU I CD1 1 
ATOM   2154 C CD2 . LEU B 1 81  ? 34.856  -16.611 1.012   1.00 35.17  ? 80  LEU I CD2 1 
ATOM   2155 N N   . LYS B 1 82  ? 37.532  -19.576 -1.451  1.00 39.63  ? 81  LYS I N   1 
ATOM   2156 C CA  . LYS B 1 82  ? 37.524  -19.413 -2.897  1.00 44.52  ? 81  LYS I CA  1 
ATOM   2157 C C   . LYS B 1 82  ? 36.085  -19.576 -3.362  1.00 46.13  ? 81  LYS I C   1 
ATOM   2158 O O   . LYS B 1 82  ? 35.509  -20.660 -3.223  1.00 43.72  ? 81  LYS I O   1 
ATOM   2159 C CB  . LYS B 1 82  ? 38.436  -20.446 -3.571  1.00 45.97  ? 81  LYS I CB  1 
ATOM   2160 C CG  . LYS B 1 82  ? 38.865  -20.098 -4.988  1.00 50.60  ? 81  LYS I CG  1 
ATOM   2161 C CD  . LYS B 1 82  ? 40.095  -19.205 -4.990  1.00 53.68  ? 81  LYS I CD  1 
ATOM   2162 C CE  . LYS B 1 82  ? 41.366  -19.982 -5.313  1.00 59.72  ? 81  LYS I CE  1 
ATOM   2163 N NZ  . LYS B 1 82  ? 42.571  -19.103 -5.334  1.00 46.55  ? 81  LYS I NZ  1 
ATOM   2164 N N   . LEU B 1 83  ? 35.505  -18.509 -3.905  1.00 42.31  ? 82  LEU I N   1 
ATOM   2165 C CA  . LEU B 1 83  ? 34.137  -18.539 -4.415  1.00 46.07  ? 82  LEU I CA  1 
ATOM   2166 C C   . LEU B 1 83  ? 34.175  -18.204 -5.897  1.00 47.55  ? 82  LEU I C   1 
ATOM   2167 O O   . LEU B 1 83  ? 34.512  -17.078 -6.273  1.00 44.47  ? 82  LEU I O   1 
ATOM   2168 C CB  . LEU B 1 83  ? 33.237  -17.564 -3.653  1.00 40.19  ? 82  LEU I CB  1 
ATOM   2169 C CG  . LEU B 1 83  ? 31.735  -17.699 -3.921  1.00 36.90  ? 82  LEU I CG  1 
ATOM   2170 C CD1 . LEU B 1 83  ? 31.126  -18.799 -3.062  1.00 43.50  ? 82  LEU I CD1 1 
ATOM   2171 C CD2 . LEU B 1 83  ? 31.029  -16.377 -3.672  1.00 39.34  ? 82  LEU I CD2 1 
ATOM   2172 N N   . ASN B 1 84  A 33.802  -19.168 -6.730  1.00 49.86  ? 82  ASN I N   1 
ATOM   2173 C CA  . ASN B 1 84  A 33.979  -19.056 -8.169  1.00 48.10  ? 82  ASN I CA  1 
ATOM   2174 C C   . ASN B 1 84  A 32.708  -18.558 -8.847  1.00 43.75  ? 82  ASN I C   1 
ATOM   2175 O O   . ASN B 1 84  A 31.596  -18.718 -8.336  1.00 44.68  ? 82  ASN I O   1 
ATOM   2176 C CB  . ASN B 1 84  A 34.380  -20.414 -8.751  1.00 41.70  ? 82  ASN I CB  1 
ATOM   2177 C CG  . ASN B 1 84  A 35.862  -20.692 -8.610  1.00 47.95  ? 82  ASN I CG  1 
ATOM   2178 O OD1 . ASN B 1 84  A 36.697  -19.993 -9.183  1.00 58.85  ? 82  ASN I OD1 1 
ATOM   2179 N ND2 . ASN B 1 84  A 36.197  -21.722 -7.839  1.00 53.83  ? 82  ASN I ND2 1 
ATOM   2180 N N   . SER B 1 85  B 32.896  -17.951 -10.019 1.00 51.70  ? 82  SER I N   1 
ATOM   2181 C CA  . SER B 1 85  B 31.807  -17.464 -10.868 1.00 42.17  ? 82  SER I CA  1 
ATOM   2182 C C   . SER B 1 85  B 30.873  -16.534 -10.092 1.00 40.90  ? 82  SER I C   1 
ATOM   2183 O O   . SER B 1 85  B 29.681  -16.797 -9.920  1.00 36.36  ? 82  SER I O   1 
ATOM   2184 C CB  . SER B 1 85  B 31.038  -18.634 -11.488 1.00 44.98  ? 82  SER I CB  1 
ATOM   2185 O OG  . SER B 1 85  B 29.685  -18.638 -11.075 1.00 49.82  ? 82  SER I OG  1 
ATOM   2186 N N   . VAL B 1 86  C 31.438  -15.426 -9.626  1.00 41.01  ? 82  VAL I N   1 
ATOM   2187 C CA  . VAL B 1 86  C 30.690  -14.496 -8.790  1.00 42.59  ? 82  VAL I CA  1 
ATOM   2188 C C   . VAL B 1 86  C 29.788  -13.622 -9.653  1.00 43.54  ? 82  VAL I C   1 
ATOM   2189 O O   . VAL B 1 86  C 30.105  -13.294 -10.802 1.00 43.63  ? 82  VAL I O   1 
ATOM   2190 C CB  . VAL B 1 86  C 31.646  -13.641 -7.934  1.00 42.34  ? 82  VAL I CB  1 
ATOM   2191 C CG1 . VAL B 1 86  C 32.413  -14.518 -6.958  1.00 41.11  ? 82  VAL I CG1 1 
ATOM   2192 C CG2 . VAL B 1 86  C 32.599  -12.857 -8.820  1.00 45.50  ? 82  VAL I CG2 1 
ATOM   2193 N N   . THR B 1 87  ? 28.642  -13.256 -9.091  1.00 43.01  ? 83  THR I N   1 
ATOM   2194 C CA  . THR B 1 87  ? 27.707  -12.303 -9.671  1.00 38.56  ? 83  THR I CA  1 
ATOM   2195 C C   . THR B 1 87  ? 27.519  -11.143 -8.697  1.00 44.84  ? 83  THR I C   1 
ATOM   2196 O O   . THR B 1 87  ? 28.061  -11.141 -7.589  1.00 44.83  ? 83  THR I O   1 
ATOM   2197 C CB  . THR B 1 87  ? 26.365  -12.968 -9.992  1.00 41.80  ? 83  THR I CB  1 
ATOM   2198 O OG1 . THR B 1 87  ? 25.692  -13.301 -8.771  1.00 45.09  ? 83  THR I OG1 1 
ATOM   2199 C CG2 . THR B 1 87  ? 26.577  -14.234 -10.811 1.00 43.82  ? 83  THR I CG2 1 
ATOM   2200 N N   . THR B 1 88  ? 26.733  -10.148 -9.117  1.00 32.29  ? 84  THR I N   1 
ATOM   2201 C CA  . THR B 1 88  ? 26.484  -8.992  -8.263  1.00 41.83  ? 84  THR I CA  1 
ATOM   2202 C C   . THR B 1 88  ? 25.770  -9.372  -6.974  1.00 39.03  ? 84  THR I C   1 
ATOM   2203 O O   . THR B 1 88  ? 25.849  -8.627  -5.990  1.00 37.82  ? 84  THR I O   1 
ATOM   2204 C CB  . THR B 1 88  ? 25.668  -7.940  -9.017  1.00 36.33  ? 84  THR I CB  1 
ATOM   2205 O OG1 . THR B 1 88  ? 24.406  -8.498  -9.404  1.00 43.15  ? 84  THR I OG1 1 
ATOM   2206 C CG2 . THR B 1 88  ? 26.417  -7.471  -10.257 1.00 35.58  ? 84  THR I CG2 1 
ATOM   2207 N N   . GLU B 1 89  ? 25.077  -10.513 -6.955  1.00 42.06  ? 85  GLU I N   1 
ATOM   2208 C CA  . GLU B 1 89  ? 24.432  -10.977 -5.733  1.00 44.04  ? 85  GLU I CA  1 
ATOM   2209 C C   . GLU B 1 89  ? 25.441  -11.407 -4.676  1.00 37.28  ? 85  GLU I C   1 
ATOM   2210 O O   . GLU B 1 89  ? 25.069  -11.558 -3.508  1.00 42.86  ? 85  GLU I O   1 
ATOM   2211 C CB  . GLU B 1 89  ? 23.483  -12.133 -6.050  1.00 44.41  ? 85  GLU I CB  1 
ATOM   2212 C CG  . GLU B 1 89  ? 22.152  -11.695 -6.632  1.00 53.80  ? 85  GLU I CG  1 
ATOM   2213 C CD  . GLU B 1 89  ? 21.272  -11.004 -5.609  1.00 67.69  ? 85  GLU I CD  1 
ATOM   2214 O OE1 . GLU B 1 89  ? 20.958  -11.630 -4.576  1.00 65.47  ? 85  GLU I OE1 1 
ATOM   2215 O OE2 . GLU B 1 89  ? 20.901  -9.835  -5.835  1.00 69.38  ? 85  GLU I OE2 1 
ATOM   2216 N N   . ASP B 1 90  ? 26.701  -11.606 -5.056  1.00 37.17  ? 86  ASP I N   1 
ATOM   2217 C CA  . ASP B 1 90  ? 27.752  -11.962 -4.113  1.00 36.31  ? 86  ASP I CA  1 
ATOM   2218 C C   . ASP B 1 90  ? 28.380  -10.749 -3.439  1.00 35.31  ? 86  ASP I C   1 
ATOM   2219 O O   . ASP B 1 90  ? 29.269  -10.919 -2.597  1.00 36.44  ? 86  ASP I O   1 
ATOM   2220 C CB  . ASP B 1 90  ? 28.834  -12.789 -4.814  1.00 35.83  ? 86  ASP I CB  1 
ATOM   2221 C CG  . ASP B 1 90  ? 28.331  -14.153 -5.243  1.00 40.31  ? 86  ASP I CG  1 
ATOM   2222 O OD1 . ASP B 1 90  ? 27.488  -14.726 -4.522  1.00 38.36  ? 86  ASP I OD1 1 
ATOM   2223 O OD2 . ASP B 1 90  ? 28.775  -14.653 -6.294  1.00 45.87  ? 86  ASP I OD2 1 
ATOM   2224 N N   . THR B 1 91  ? 27.953  -9.539  -3.795  1.00 30.86  ? 87  THR I N   1 
ATOM   2225 C CA  . THR B 1 91  ? 28.378  -8.348  -3.071  1.00 33.10  ? 87  THR I CA  1 
ATOM   2226 C C   . THR B 1 91  ? 27.944  -8.459  -1.618  1.00 36.07  ? 87  THR I C   1 
ATOM   2227 O O   . THR B 1 91  ? 26.746  -8.540  -1.330  1.00 33.79  ? 87  THR I O   1 
ATOM   2228 C CB  . THR B 1 91  ? 27.771  -7.100  -3.711  1.00 34.00  ? 87  THR I CB  1 
ATOM   2229 O OG1 . THR B 1 91  ? 28.218  -6.986  -5.069  1.00 29.69  ? 87  THR I OG1 1 
ATOM   2230 C CG2 . THR B 1 91  ? 28.168  -5.852  -2.938  1.00 30.12  ? 87  THR I CG2 1 
ATOM   2231 N N   . ALA B 1 92  ? 28.910  -8.456  -0.701  1.00 36.68  ? 88  ALA I N   1 
ATOM   2232 C CA  . ALA B 1 92  ? 28.584  -8.690  0.702   1.00 38.29  ? 88  ALA I CA  1 
ATOM   2233 C C   . ALA B 1 92  ? 29.808  -8.417  1.563   1.00 33.59  ? 88  ALA I C   1 
ATOM   2234 O O   . ALA B 1 92  ? 30.925  -8.255  1.065   1.00 31.97  ? 88  ALA I O   1 
ATOM   2235 C CB  . ALA B 1 92  ? 28.085  -10.121 0.931   1.00 32.13  ? 88  ALA I CB  1 
ATOM   2236 N N   . THR B 1 93  ? 29.578  -8.367  2.872   1.00 33.22  ? 89  THR I N   1 
ATOM   2237 C CA  . THR B 1 93  ? 30.657  -8.306  3.849   1.00 31.61  ? 89  THR I CA  1 
ATOM   2238 C C   . THR B 1 93  ? 30.964  -9.724  4.313   1.00 31.29  ? 89  THR I C   1 
ATOM   2239 O O   . THR B 1 93  ? 30.078  -10.420 4.818   1.00 35.49  ? 89  THR I O   1 
ATOM   2240 C CB  . THR B 1 93  ? 30.275  -7.421  5.033   1.00 32.62  ? 89  THR I CB  1 
ATOM   2241 O OG1 . THR B 1 93  ? 30.062  -6.079  4.577   1.00 40.47  ? 89  THR I OG1 1 
ATOM   2242 C CG2 . THR B 1 93  ? 31.381  -7.425  6.076   1.00 35.71  ? 89  THR I CG2 1 
ATOM   2243 N N   . TYR B 1 94  ? 32.211  -10.148 4.147   1.00 29.69  ? 90  TYR I N   1 
ATOM   2244 C CA  . TYR B 1 94  ? 32.619  -11.514 4.439   1.00 31.66  ? 90  TYR I CA  1 
ATOM   2245 C C   . TYR B 1 94  ? 33.387  -11.557 5.752   1.00 31.42  ? 90  TYR I C   1 
ATOM   2246 O O   . TYR B 1 94  ? 34.300  -10.752 5.973   1.00 35.38  ? 90  TYR I O   1 
ATOM   2247 C CB  . TYR B 1 94  ? 33.473  -12.070 3.299   1.00 32.33  ? 90  TYR I CB  1 
ATOM   2248 C CG  . TYR B 1 94  ? 32.698  -12.333 2.025   1.00 40.38  ? 90  TYR I CG  1 
ATOM   2249 C CD1 . TYR B 1 94  ? 32.249  -11.286 1.229   1.00 35.31  ? 90  TYR I CD1 1 
ATOM   2250 C CD2 . TYR B 1 94  ? 32.422  -13.628 1.613   1.00 34.92  ? 90  TYR I CD2 1 
ATOM   2251 C CE1 . TYR B 1 94  ? 31.540  -11.524 0.064   1.00 36.17  ? 90  TYR I CE1 1 
ATOM   2252 C CE2 . TYR B 1 94  ? 31.718  -13.874 0.447   1.00 36.72  ? 90  TYR I CE2 1 
ATOM   2253 C CZ  . TYR B 1 94  ? 31.277  -12.820 -0.321  1.00 40.16  ? 90  TYR I CZ  1 
ATOM   2254 O OH  . TYR B 1 94  ? 30.576  -13.066 -1.479  1.00 36.77  ? 90  TYR I OH  1 
ATOM   2255 N N   . TYR B 1 95  ? 33.013  -12.496 6.618   1.00 31.26  ? 91  TYR I N   1 
ATOM   2256 C CA  . TYR B 1 95  ? 33.637  -12.708 7.913   1.00 30.45  ? 91  TYR I CA  1 
ATOM   2257 C C   . TYR B 1 95  ? 34.188  -14.124 7.985   1.00 33.62  ? 91  TYR I C   1 
ATOM   2258 O O   . TYR B 1 95  ? 33.551  -15.074 7.509   1.00 33.14  ? 91  TYR I O   1 
ATOM   2259 C CB  . TYR B 1 95  ? 32.634  -12.528 9.067   1.00 31.55  ? 91  TYR I CB  1 
ATOM   2260 C CG  . TYR B 1 95  ? 31.962  -11.178 9.169   1.00 31.07  ? 91  TYR I CG  1 
ATOM   2261 C CD1 . TYR B 1 95  ? 32.550  -10.143 9.879   1.00 31.96  ? 91  TYR I CD1 1 
ATOM   2262 C CD2 . TYR B 1 95  ? 30.723  -10.951 8.584   1.00 32.94  ? 91  TYR I CD2 1 
ATOM   2263 C CE1 . TYR B 1 95  ? 31.935  -8.911  9.988   1.00 29.85  ? 91  TYR I CE1 1 
ATOM   2264 C CE2 . TYR B 1 95  ? 30.098  -9.721  8.689   1.00 33.49  ? 91  TYR I CE2 1 
ATOM   2265 C CZ  . TYR B 1 95  ? 30.709  -8.705  9.393   1.00 33.10  ? 91  TYR I CZ  1 
ATOM   2266 O OH  . TYR B 1 95  ? 30.098  -7.477  9.504   1.00 35.85  ? 91  TYR I OH  1 
ATOM   2267 N N   . CYS B 1 96  ? 35.369  -14.261 8.576   1.00 34.56  ? 92  CYS I N   1 
ATOM   2268 C CA  . CYS B 1 96  ? 35.839  -15.558 9.032   1.00 37.61  ? 92  CYS I CA  1 
ATOM   2269 C C   . CYS B 1 96  ? 35.644  -15.640 10.538  1.00 37.05  ? 92  CYS I C   1 
ATOM   2270 O O   . CYS B 1 96  ? 35.718  -14.634 11.249  1.00 41.56  ? 92  CYS I O   1 
ATOM   2271 C CB  . CYS B 1 96  ? 37.304  -15.803 8.672   1.00 37.64  ? 92  CYS I CB  1 
ATOM   2272 S SG  . CYS B 1 96  ? 38.520  -14.602 9.244   1.00 39.73  ? 92  CYS I SG  1 
ATOM   2273 N N   . ALA B 1 97  ? 35.378  -16.849 11.021  1.00 30.20  ? 93  ALA I N   1 
ATOM   2274 C CA  . ALA B 1 97  ? 35.063  -17.012 12.431  1.00 37.17  ? 93  ALA I CA  1 
ATOM   2275 C C   . ALA B 1 97  ? 35.535  -18.375 12.908  1.00 34.94  ? 93  ALA I C   1 
ATOM   2276 O O   . ALA B 1 97  ? 35.701  -19.308 12.120  1.00 37.05  ? 93  ALA I O   1 
ATOM   2277 C CB  . ALA B 1 97  ? 33.560  -16.849 12.691  1.00 29.87  ? 93  ALA I CB  1 
ATOM   2278 N N   . ARG B 1 98  ? 35.762  -18.475 14.216  1.00 37.56  ? 94  ARG I N   1 
ATOM   2279 C CA  . ARG B 1 98  ? 35.993  -19.754 14.875  1.00 39.29  ? 94  ARG I CA  1 
ATOM   2280 C C   . ARG B 1 98  ? 34.689  -20.157 15.549  1.00 34.61  ? 94  ARG I C   1 
ATOM   2281 O O   . ARG B 1 98  ? 34.251  -19.501 16.500  1.00 41.33  ? 94  ARG I O   1 
ATOM   2282 C CB  . ARG B 1 98  ? 37.124  -19.675 15.897  1.00 34.61  ? 94  ARG I CB  1 
ATOM   2283 C CG  . ARG B 1 98  ? 37.479  -21.041 16.463  1.00 42.75  ? 94  ARG I CG  1 
ATOM   2284 C CD  . ARG B 1 98  ? 38.357  -20.978 17.700  1.00 44.28  ? 94  ARG I CD  1 
ATOM   2285 N NE  . ARG B 1 98  ? 37.585  -20.733 18.912  1.00 46.51  ? 94  ARG I NE  1 
ATOM   2286 C CZ  . ARG B 1 98  ? 38.102  -20.699 20.132  1.00 48.39  ? 94  ARG I CZ  1 
ATOM   2287 N NH1 . ARG B 1 98  ? 39.394  -20.891 20.340  1.00 48.13  ? 94  ARG I NH1 1 
ATOM   2288 N NH2 . ARG B 1 98  ? 37.302  -20.474 21.171  1.00 40.94  ? 94  ARG I NH2 1 
ATOM   2289 N N   . GLY B 1 99  ? 34.081  -21.240 15.067  1.00 36.64  ? 95  GLY I N   1 
ATOM   2290 C CA  . GLY B 1 99  ? 32.778  -21.638 15.558  1.00 36.70  ? 95  GLY I CA  1 
ATOM   2291 C C   . GLY B 1 99  ? 31.797  -20.487 15.490  1.00 44.90  ? 95  GLY I C   1 
ATOM   2292 O O   . GLY B 1 99  ? 31.283  -20.157 14.417  1.00 50.04  ? 95  GLY I O   1 
ATOM   2293 N N   . GLY B 1 100 ? 31.535  -19.867 16.637  1.00 42.71  ? 96  GLY I N   1 
ATOM   2294 C CA  . GLY B 1 100 ? 30.716  -18.674 16.688  1.00 36.67  ? 96  GLY I CA  1 
ATOM   2295 C C   . GLY B 1 100 ? 31.164  -17.690 17.751  1.00 40.69  ? 96  GLY I C   1 
ATOM   2296 O O   . GLY B 1 100 ? 30.532  -16.647 17.940  1.00 36.95  ? 96  GLY I O   1 
ATOM   2297 N N   . ASP B 1 101 ? 32.257  -18.002 18.448  1.00 35.51  ? 101 ASP I N   1 
ATOM   2298 C CA  . ASP B 1 101 ? 32.687  -17.179 19.572  1.00 42.73  ? 101 ASP I CA  1 
ATOM   2299 C C   . ASP B 1 101 ? 33.636  -16.056 19.170  1.00 40.61  ? 101 ASP I C   1 
ATOM   2300 O O   . ASP B 1 101 ? 33.600  -14.982 19.783  1.00 44.65  ? 101 ASP I O   1 
ATOM   2301 C CB  . ASP B 1 101 ? 33.337  -18.049 20.656  1.00 43.59  ? 101 ASP I CB  1 
ATOM   2302 C CG  . ASP B 1 101 ? 34.334  -19.047 20.097  1.00 47.73  ? 101 ASP I CG  1 
ATOM   2303 O OD1 . ASP B 1 101 ? 34.944  -18.764 19.048  1.00 44.92  ? 101 ASP I OD1 1 
ATOM   2304 O OD2 . ASP B 1 101 ? 34.510  -20.118 20.717  1.00 53.84  ? 101 ASP I OD2 1 
ATOM   2305 N N   . TYR B 1 102 ? 34.483  -16.267 18.164  1.00 34.48  ? 102 TYR I N   1 
ATOM   2306 C CA  . TYR B 1 102 ? 35.439  -15.259 17.719  1.00 39.25  ? 102 TYR I CA  1 
ATOM   2307 C C   . TYR B 1 102 ? 35.258  -15.005 16.229  1.00 43.14  ? 102 TYR I C   1 
ATOM   2308 O O   . TYR B 1 102 ? 35.430  -15.917 15.413  1.00 36.25  ? 102 TYR I O   1 
ATOM   2309 C CB  . TYR B 1 102 ? 36.876  -15.686 18.023  1.00 42.51  ? 102 TYR I CB  1 
ATOM   2310 C CG  . TYR B 1 102 ? 37.208  -15.673 19.498  1.00 49.11  ? 102 TYR I CG  1 
ATOM   2311 C CD1 . TYR B 1 102 ? 37.554  -14.490 20.139  1.00 49.22  ? 102 TYR I CD1 1 
ATOM   2312 C CD2 . TYR B 1 102 ? 37.173  -16.839 20.251  1.00 46.98  ? 102 TYR I CD2 1 
ATOM   2313 C CE1 . TYR B 1 102 ? 37.857  -14.468 21.487  1.00 50.77  ? 102 TYR I CE1 1 
ATOM   2314 C CE2 . TYR B 1 102 ? 37.474  -16.826 21.600  1.00 48.86  ? 102 TYR I CE2 1 
ATOM   2315 C CZ  . TYR B 1 102 ? 37.815  -15.638 22.212  1.00 50.58  ? 102 TYR I CZ  1 
ATOM   2316 O OH  . TYR B 1 102 ? 38.115  -15.619 23.555  1.00 42.47  ? 102 TYR I OH  1 
ATOM   2317 N N   . TRP B 1 103 ? 34.921  -13.765 15.883  1.00 37.18  ? 103 TRP I N   1 
ATOM   2318 C CA  . TRP B 1 103 ? 34.741  -13.324 14.508  1.00 35.97  ? 103 TRP I CA  1 
ATOM   2319 C C   . TRP B 1 103 ? 35.871  -12.384 14.107  1.00 33.99  ? 103 TRP I C   1 
ATOM   2320 O O   . TRP B 1 103 ? 36.462  -11.705 14.953  1.00 34.87  ? 103 TRP I O   1 
ATOM   2321 C CB  . TRP B 1 103 ? 33.406  -12.589 14.325  1.00 31.66  ? 103 TRP I CB  1 
ATOM   2322 C CG  . TRP B 1 103 ? 32.179  -13.417 14.537  1.00 34.02  ? 103 TRP I CG  1 
ATOM   2323 C CD1 . TRP B 1 103 ? 31.828  -14.098 15.666  1.00 37.96  ? 103 TRP I CD1 1 
ATOM   2324 C CD2 . TRP B 1 103 ? 31.119  -13.623 13.597  1.00 35.34  ? 103 TRP I CD2 1 
ATOM   2325 N NE1 . TRP B 1 103 ? 30.620  -14.729 15.480  1.00 37.85  ? 103 TRP I NE1 1 
ATOM   2326 C CE2 . TRP B 1 103 ? 30.166  -14.453 14.217  1.00 32.80  ? 103 TRP I CE2 1 
ATOM   2327 C CE3 . TRP B 1 103 ? 30.888  -13.192 12.286  1.00 30.67  ? 103 TRP I CE3 1 
ATOM   2328 C CZ2 . TRP B 1 103 ? 28.999  -14.860 13.573  1.00 39.56  ? 103 TRP I CZ2 1 
ATOM   2329 C CZ3 . TRP B 1 103 ? 29.729  -13.597 11.648  1.00 32.05  ? 103 TRP I CZ3 1 
ATOM   2330 C CH2 . TRP B 1 103 ? 28.799  -14.422 12.292  1.00 27.75  ? 103 TRP I CH2 1 
ATOM   2331 N N   . GLY B 1 104 ? 36.175  -12.355 12.808  1.00 38.52  ? 104 GLY I N   1 
ATOM   2332 C CA  . GLY B 1 104 ? 37.061  -11.343 12.277  1.00 38.82  ? 104 GLY I CA  1 
ATOM   2333 C C   . GLY B 1 104 ? 36.349  -10.011 12.137  1.00 38.75  ? 104 GLY I C   1 
ATOM   2334 O O   . GLY B 1 104 ? 35.171  -9.859  12.459  1.00 33.86  ? 104 GLY I O   1 
ATOM   2335 N N   . GLN B 1 105 ? 37.090  -9.018  11.642  1.00 40.49  ? 105 GLN I N   1 
ATOM   2336 C CA  . GLN B 1 105 ? 36.491  -7.702  11.448  1.00 40.65  ? 105 GLN I CA  1 
ATOM   2337 C C   . GLN B 1 105 ? 35.555  -7.675  10.251  1.00 38.51  ? 105 GLN I C   1 
ATOM   2338 O O   . GLN B 1 105 ? 34.629  -6.857  10.207  1.00 39.52  ? 105 GLN I O   1 
ATOM   2339 C CB  . GLN B 1 105 ? 37.575  -6.655  11.262  1.00 41.70  ? 105 GLN I CB  1 
ATOM   2340 C CG  . GLN B 1 105 ? 38.430  -6.390  12.488  1.00 54.49  ? 105 GLN I CG  1 
ATOM   2341 C CD  . GLN B 1 105 ? 39.446  -7.488  12.706  1.00 57.82  ? 105 GLN I CD  1 
ATOM   2342 O OE1 . GLN B 1 105 ? 39.629  -7.967  13.813  1.00 58.64  ? 105 GLN I OE1 1 
ATOM   2343 N NE2 . GLN B 1 105 ? 40.036  -7.952  11.626  1.00 60.76  ? 105 GLN I NE2 1 
ATOM   2344 N N   . GLY B 1 106 ? 35.794  -8.534  9.271   1.00 32.43  ? 106 GLY I N   1 
ATOM   2345 C CA  . GLY B 1 106 ? 34.980  -8.556  8.080   1.00 33.78  ? 106 GLY I CA  1 
ATOM   2346 C C   . GLY B 1 106 ? 35.503  -7.639  7.002   1.00 37.53  ? 106 GLY I C   1 
ATOM   2347 O O   . GLY B 1 106 ? 35.994  -6.546  7.296   1.00 37.69  ? 106 GLY I O   1 
ATOM   2348 N N   . THR B 1 107 ? 35.437  -8.086  5.750   1.00 34.98  ? 107 THR I N   1 
ATOM   2349 C CA  . THR B 1 107 ? 35.906  -7.301  4.618   1.00 35.70  ? 107 THR I CA  1 
ATOM   2350 C C   . THR B 1 107 ? 34.785  -7.153  3.601   1.00 37.51  ? 107 THR I C   1 
ATOM   2351 O O   . THR B 1 107 ? 34.064  -8.111  3.310   1.00 35.11  ? 107 THR I O   1 
ATOM   2352 C CB  . THR B 1 107 ? 37.147  -7.948  3.968   1.00 31.67  ? 107 THR I CB  1 
ATOM   2353 O OG1 . THR B 1 107 ? 37.507  -7.225  2.784   1.00 42.49  ? 107 THR I OG1 1 
ATOM   2354 C CG2 . THR B 1 107 ? 36.884  -9.408  3.623   1.00 30.97  ? 107 THR I CG2 1 
ATOM   2355 N N   . SER B 1 108 ? 34.630  -5.940  3.079   1.00 32.95  ? 108 SER I N   1 
ATOM   2356 C CA  . SER B 1 108 ? 33.585  -5.658  2.105   1.00 38.02  ? 108 SER I CA  1 
ATOM   2357 C C   . SER B 1 108 ? 34.048  -6.064  0.712   1.00 38.51  ? 108 SER I C   1 
ATOM   2358 O O   . SER B 1 108 ? 35.112  -5.637  0.254   1.00 39.73  ? 108 SER I O   1 
ATOM   2359 C CB  . SER B 1 108 ? 33.224  -4.173  2.136   1.00 36.49  ? 108 SER I CB  1 
ATOM   2360 O OG  . SER B 1 108 ? 32.282  -3.849  1.130   1.00 51.14  ? 108 SER I OG  1 
ATOM   2361 N N   . VAL B 1 109 ? 33.256  -6.898  0.039   1.00 37.02  ? 109 VAL I N   1 
ATOM   2362 C CA  . VAL B 1 109 ? 33.550  -7.353  -1.313  1.00 37.51  ? 109 VAL I CA  1 
ATOM   2363 C C   . VAL B 1 109 ? 32.432  -6.868  -2.223  1.00 38.15  ? 109 VAL I C   1 
ATOM   2364 O O   . VAL B 1 109 ? 31.257  -7.203  -2.010  1.00 37.70  ? 109 VAL I O   1 
ATOM   2365 C CB  . VAL B 1 109 ? 33.697  -8.881  -1.385  1.00 35.90  ? 109 VAL I CB  1 
ATOM   2366 C CG1 . VAL B 1 109 ? 33.843  -9.330  -2.830  1.00 37.19  ? 109 VAL I CG1 1 
ATOM   2367 C CG2 . VAL B 1 109 ? 34.888  -9.334  -0.557  1.00 38.21  ? 109 VAL I CG2 1 
ATOM   2368 N N   . THR B 1 110 ? 32.799  -6.075  -3.227  1.00 33.66  ? 110 THR I N   1 
ATOM   2369 C CA  . THR B 1 110 ? 31.879  -5.564  -4.233  1.00 35.49  ? 110 THR I CA  1 
ATOM   2370 C C   . THR B 1 110 ? 32.131  -6.301  -5.540  1.00 36.11  ? 110 THR I C   1 
ATOM   2371 O O   . THR B 1 110 ? 33.250  -6.276  -6.064  1.00 36.96  ? 110 THR I O   1 
ATOM   2372 C CB  . THR B 1 110 ? 32.061  -4.058  -4.429  1.00 37.43  ? 110 THR I CB  1 
ATOM   2373 O OG1 . THR B 1 110 ? 31.766  -3.373  -3.206  1.00 35.04  ? 110 THR I OG1 1 
ATOM   2374 C CG2 . THR B 1 110 ? 31.146  -3.546  -5.534  1.00 33.03  ? 110 THR I CG2 1 
ATOM   2375 N N   . VAL B 1 111 ? 31.099  -6.957  -6.058  1.00 33.01  ? 111 VAL I N   1 
ATOM   2376 C CA  . VAL B 1 111 ? 31.166  -7.629  -7.349  1.00 36.69  ? 111 VAL I CA  1 
ATOM   2377 C C   . VAL B 1 111 ? 30.464  -6.734  -8.360  1.00 38.04  ? 111 VAL I C   1 
ATOM   2378 O O   . VAL B 1 111 ? 29.238  -6.584  -8.329  1.00 39.01  ? 111 VAL I O   1 
ATOM   2379 C CB  . VAL B 1 111 ? 30.536  -9.026  -7.302  1.00 35.87  ? 111 VAL I CB  1 
ATOM   2380 C CG1 . VAL B 1 111 ? 30.672  -9.702  -8.657  1.00 42.32  ? 111 VAL I CG1 1 
ATOM   2381 C CG2 . VAL B 1 111 ? 31.190  -9.865  -6.214  1.00 35.99  ? 111 VAL I CG2 1 
ATOM   2382 N N   . SER B 1 112 ? 31.241  -6.136  -9.258  1.00 33.52  ? 112 SER I N   1 
ATOM   2383 C CA  . SER B 1 112 ? 30.700  -5.186  -10.216 1.00 36.53  ? 112 SER I CA  1 
ATOM   2384 C C   . SER B 1 112 ? 31.571  -5.174  -11.460 1.00 39.14  ? 112 SER I C   1 
ATOM   2385 O O   . SER B 1 112 ? 32.780  -5.412  -11.394 1.00 39.80  ? 112 SER I O   1 
ATOM   2386 C CB  . SER B 1 112 ? 30.614  -3.776  -9.618  1.00 32.99  ? 112 SER I CB  1 
ATOM   2387 O OG  . SER B 1 112 ? 30.334  -2.812  -10.619 1.00 40.00  ? 112 SER I OG  1 
ATOM   2388 N N   . SER B 1 113 ? 30.941  -4.894  -12.597 1.00 38.71  ? 113 SER I N   1 
ATOM   2389 C CA  . SER B 1 113 ? 31.652  -4.711  -13.854 1.00 41.90  ? 113 SER I CA  1 
ATOM   2390 C C   . SER B 1 113 ? 32.142  -3.282  -14.043 1.00 44.52  ? 113 SER I C   1 
ATOM   2391 O O   . SER B 1 113 ? 32.830  -3.001  -15.030 1.00 44.05  ? 113 SER I O   1 
ATOM   2392 C CB  . SER B 1 113 ? 30.753  -5.106  -15.031 1.00 36.44  ? 113 SER I CB  1 
ATOM   2393 O OG  . SER B 1 113 ? 29.614  -4.267  -15.111 1.00 42.03  ? 113 SER I OG  1 
ATOM   2394 N N   . ALA B 1 114 ? 31.802  -2.379  -13.127 1.00 37.63  ? 114 ALA I N   1 
ATOM   2395 C CA  . ALA B 1 114 ? 32.165  -0.979  -13.264 1.00 36.16  ? 114 ALA I CA  1 
ATOM   2396 C C   . ALA B 1 114 ? 33.651  -0.778  -12.979 1.00 41.41  ? 114 ALA I C   1 
ATOM   2397 O O   . ALA B 1 114 ? 34.297  -1.572  -12.289 1.00 43.67  ? 114 ALA I O   1 
ATOM   2398 C CB  . ALA B 1 114 ? 31.325  -0.110  -12.327 1.00 36.44  ? 114 ALA I CB  1 
ATOM   2399 N N   . SER B 1 115 ? 34.190  0.304   -13.527 1.00 44.69  ? 115 SER I N   1 
ATOM   2400 C CA  . SER B 1 115 ? 35.580  0.689   -13.341 1.00 45.51  ? 115 SER I CA  1 
ATOM   2401 C C   . SER B 1 115 ? 35.668  1.974   -12.528 1.00 38.82  ? 115 SER I C   1 
ATOM   2402 O O   . SER B 1 115 ? 34.684  2.700   -12.361 1.00 34.84  ? 115 SER I O   1 
ATOM   2403 C CB  . SER B 1 115 ? 36.288  0.864   -14.688 1.00 39.88  ? 115 SER I CB  1 
ATOM   2404 O OG  . SER B 1 115 ? 36.271  -0.348  -15.423 1.00 40.73  ? 115 SER I OG  1 
ATOM   2405 N N   . THR B 1 116 ? 36.867  2.231   -12.007 1.00 36.60  ? 116 THR I N   1 
ATOM   2406 C CA  . THR B 1 116 ? 37.101  3.398   -11.164 1.00 40.18  ? 116 THR I CA  1 
ATOM   2407 C C   . THR B 1 116 ? 36.694  4.678   -11.884 1.00 41.99  ? 116 THR I C   1 
ATOM   2408 O O   . THR B 1 116 ? 37.055  4.898   -13.044 1.00 44.53  ? 116 THR I O   1 
ATOM   2409 C CB  . THR B 1 116 ? 38.576  3.470   -10.764 1.00 44.45  ? 116 THR I CB  1 
ATOM   2410 O OG1 . THR B 1 116 ? 38.969  2.235   -10.152 1.00 50.55  ? 116 THR I OG1 1 
ATOM   2411 C CG2 . THR B 1 116 ? 38.812  4.613   -9.787  1.00 37.53  ? 116 THR I CG2 1 
ATOM   2412 N N   . LYS B 1 117 ? 35.939  5.524   -11.186 1.00 38.51  ? 117 LYS I N   1 
ATOM   2413 C CA  . LYS B 1 117 ? 35.462  6.778   -11.751 1.00 40.03  ? 117 LYS I CA  1 
ATOM   2414 C C   . LYS B 1 117 ? 35.238  7.776   -10.626 1.00 45.39  ? 117 LYS I C   1 
ATOM   2415 O O   . LYS B 1 117 ? 34.589  7.452   -9.627  1.00 39.60  ? 117 LYS I O   1 
ATOM   2416 C CB  . LYS B 1 117 ? 34.171  6.566   -12.549 1.00 39.32  ? 117 LYS I CB  1 
ATOM   2417 C CG  . LYS B 1 117 ? 33.501  7.848   -13.012 1.00 37.99  ? 117 LYS I CG  1 
ATOM   2418 C CD  . LYS B 1 117 ? 32.355  7.550   -13.965 1.00 41.60  ? 117 LYS I CD  1 
ATOM   2419 C CE  . LYS B 1 117 ? 31.645  8.821   -14.406 1.00 36.92  ? 117 LYS I CE  1 
ATOM   2420 N NZ  . LYS B 1 117 ? 32.094  10.016  -13.641 1.00 45.16  ? 117 LYS I NZ  1 
ATOM   2421 N N   . GLY B 1 118 ? 35.782  8.979   -10.789 1.00 42.02  ? 118 GLY I N   1 
ATOM   2422 C CA  . GLY B 1 118 ? 35.598  10.042  -9.830  1.00 43.43  ? 118 GLY I CA  1 
ATOM   2423 C C   . GLY B 1 118 ? 34.198  10.618  -9.872  1.00 41.24  ? 118 GLY I C   1 
ATOM   2424 O O   . GLY B 1 118 ? 33.478  10.492  -10.867 1.00 38.23  ? 118 GLY I O   1 
ATOM   2425 N N   . PRO B 1 119 ? 33.782  11.258  -8.784  1.00 41.15  ? 119 PRO I N   1 
ATOM   2426 C CA  . PRO B 1 119 ? 32.416  11.773  -8.697  1.00 37.92  ? 119 PRO I CA  1 
ATOM   2427 C C   . PRO B 1 119 ? 32.272  13.185  -9.248  1.00 40.50  ? 119 PRO I C   1 
ATOM   2428 O O   . PRO B 1 119 ? 33.226  13.961  -9.326  1.00 38.55  ? 119 PRO I O   1 
ATOM   2429 C CB  . PRO B 1 119 ? 32.152  11.761  -7.187  1.00 36.97  ? 119 PRO I CB  1 
ATOM   2430 C CG  . PRO B 1 119 ? 33.488  12.067  -6.601  1.00 38.64  ? 119 PRO I CG  1 
ATOM   2431 C CD  . PRO B 1 119 ? 34.504  11.400  -7.506  1.00 39.11  ? 119 PRO I CD  1 
ATOM   2432 N N   . SER B 1 120 ? 31.040  13.501  -9.637  1.00 34.91  ? 120 SER I N   1 
ATOM   2433 C CA  . SER B 1 120 ? 30.640  14.877  -9.897  1.00 38.85  ? 120 SER I CA  1 
ATOM   2434 C C   . SER B 1 120 ? 29.991  15.445  -8.641  1.00 41.11  ? 120 SER I C   1 
ATOM   2435 O O   . SER B 1 120 ? 29.130  14.799  -8.034  1.00 37.40  ? 120 SER I O   1 
ATOM   2436 C CB  . SER B 1 120 ? 29.674  14.949  -11.080 1.00 39.15  ? 120 SER I CB  1 
ATOM   2437 O OG  . SER B 1 120 ? 30.278  14.459  -12.264 1.00 48.25  ? 120 SER I OG  1 
ATOM   2438 N N   . VAL B 1 121 ? 30.402  16.648  -8.254  1.00 36.41  ? 121 VAL I N   1 
ATOM   2439 C CA  . VAL B 1 121 ? 29.900  17.300  -7.049  1.00 37.48  ? 121 VAL I CA  1 
ATOM   2440 C C   . VAL B 1 121 ? 29.062  18.496  -7.476  1.00 41.46  ? 121 VAL I C   1 
ATOM   2441 O O   . VAL B 1 121 ? 29.591  19.490  -7.989  1.00 43.05  ? 121 VAL I O   1 
ATOM   2442 C CB  . VAL B 1 121 ? 31.037  17.721  -6.109  1.00 40.55  ? 121 VAL I CB  1 
ATOM   2443 C CG1 . VAL B 1 121 ? 30.467  18.295  -4.820  1.00 33.26  ? 121 VAL I CG1 1 
ATOM   2444 C CG2 . VAL B 1 121 ? 31.942  16.536  -5.814  1.00 36.59  ? 121 VAL I CG2 1 
ATOM   2445 N N   . PHE B 1 122 ? 27.752  18.399  -7.266  1.00 40.24  ? 122 PHE I N   1 
ATOM   2446 C CA  . PHE B 1 122 ? 26.835  19.476  -7.593  1.00 41.55  ? 122 PHE I CA  1 
ATOM   2447 C C   . PHE B 1 122 ? 26.310  20.133  -6.321  1.00 43.85  ? 122 PHE I C   1 
ATOM   2448 O O   . PHE B 1 122 ? 26.167  19.471  -5.290  1.00 38.73  ? 122 PHE I O   1 
ATOM   2449 C CB  . PHE B 1 122 ? 25.652  18.965  -8.422  1.00 39.95  ? 122 PHE I CB  1 
ATOM   2450 C CG  . PHE B 1 122 ? 26.058  18.241  -9.671  1.00 40.37  ? 122 PHE I CG  1 
ATOM   2451 C CD1 . PHE B 1 122 ? 26.757  18.898  -10.671 1.00 44.82  ? 122 PHE I CD1 1 
ATOM   2452 C CD2 . PHE B 1 122 ? 25.740  16.905  -9.847  1.00 36.10  ? 122 PHE I CD2 1 
ATOM   2453 C CE1 . PHE B 1 122 ? 27.135  18.234  -11.822 1.00 43.55  ? 122 PHE I CE1 1 
ATOM   2454 C CE2 . PHE B 1 122 ? 26.114  16.236  -10.997 1.00 42.54  ? 122 PHE I CE2 1 
ATOM   2455 C CZ  . PHE B 1 122 ? 26.812  16.902  -11.986 1.00 43.09  ? 122 PHE I CZ  1 
ATOM   2456 N N   . PRO B 1 123 ? 26.032  21.431  -6.349  1.00 39.39  ? 123 PRO I N   1 
ATOM   2457 C CA  . PRO B 1 123 ? 25.514  22.093  -5.150  1.00 40.85  ? 123 PRO I CA  1 
ATOM   2458 C C   . PRO B 1 123 ? 24.024  21.851  -4.968  1.00 39.40  ? 123 PRO I C   1 
ATOM   2459 O O   . PRO B 1 123 ? 23.260  21.738  -5.929  1.00 38.18  ? 123 PRO I O   1 
ATOM   2460 C CB  . PRO B 1 123 ? 25.802  23.574  -5.420  1.00 37.01  ? 123 PRO I CB  1 
ATOM   2461 C CG  . PRO B 1 123 ? 25.720  23.687  -6.904  1.00 46.99  ? 123 PRO I CG  1 
ATOM   2462 C CD  . PRO B 1 123 ? 26.247  22.382  -7.455  1.00 45.82  ? 123 PRO I CD  1 
ATOM   2463 N N   . LEU B 1 124 ? 23.618  21.772  -3.705  1.00 34.56  ? 124 LEU I N   1 
ATOM   2464 C CA  . LEU B 1 124 ? 22.219  21.761  -3.299  1.00 37.16  ? 124 LEU I CA  1 
ATOM   2465 C C   . LEU B 1 124 ? 22.023  23.080  -2.559  1.00 32.06  ? 124 LEU I C   1 
ATOM   2466 O O   . LEU B 1 124 ? 22.237  23.165  -1.348  1.00 34.60  ? 124 LEU I O   1 
ATOM   2467 C CB  . LEU B 1 124 ? 21.896  20.556  -2.420  1.00 36.31  ? 124 LEU I CB  1 
ATOM   2468 C CG  . LEU B 1 124 ? 22.139  19.173  -3.026  1.00 39.96  ? 124 LEU I CG  1 
ATOM   2469 C CD1 . LEU B 1 124 ? 22.110  18.106  -1.944  1.00 35.54  ? 124 LEU I CD1 1 
ATOM   2470 C CD2 . LEU B 1 124 ? 21.111  18.875  -4.103  1.00 35.74  ? 124 LEU I CD2 1 
ATOM   2471 N N   . ALA B 1 125 ? 21.643  24.112  -3.309  1.00 41.14  ? 125 ALA I N   1 
ATOM   2472 C CA  . ALA B 1 125 ? 21.653  25.493  -2.851  1.00 38.63  ? 125 ALA I CA  1 
ATOM   2473 C C   . ALA B 1 125 ? 20.418  25.791  -2.005  1.00 40.12  ? 125 ALA I C   1 
ATOM   2474 O O   . ALA B 1 125 ? 19.330  25.284  -2.290  1.00 43.10  ? 125 ALA I O   1 
ATOM   2475 C CB  . ALA B 1 125 ? 21.707  26.449  -4.039  1.00 43.62  ? 125 ALA I CB  1 
ATOM   2476 N N   . PRO B 1 126 ? 20.558  26.609  -0.964  1.00 41.65  ? 126 PRO I N   1 
ATOM   2477 C CA  . PRO B 1 126 ? 19.388  26.999  -0.174  1.00 42.06  ? 126 PRO I CA  1 
ATOM   2478 C C   . PRO B 1 126 ? 18.549  28.039  -0.899  1.00 49.78  ? 126 PRO I C   1 
ATOM   2479 O O   . PRO B 1 126 ? 19.069  28.965  -1.527  1.00 45.44  ? 126 PRO I O   1 
ATOM   2480 C CB  . PRO B 1 126 ? 20.006  27.578  1.104   1.00 35.94  ? 126 PRO I CB  1 
ATOM   2481 C CG  . PRO B 1 126 ? 21.320  28.119  0.657   1.00 44.40  ? 126 PRO I CG  1 
ATOM   2482 C CD  . PRO B 1 126 ? 21.803  27.200  -0.441  1.00 40.70  ? 126 PRO I CD  1 
ATOM   2483 N N   . SER B 1 127 ? 17.234  27.874  -0.804  1.00 50.48  ? 127 SER I N   1 
ATOM   2484 C CA  . SER B 1 127 ? 16.284  28.813  -1.382  1.00 53.98  ? 127 SER I CA  1 
ATOM   2485 C C   . SER B 1 127 ? 15.109  28.941  -0.422  1.00 56.71  ? 127 SER I C   1 
ATOM   2486 O O   . SER B 1 127 ? 15.122  28.392  0.684   1.00 55.09  ? 127 SER I O   1 
ATOM   2487 C CB  . SER B 1 127 ? 15.846  28.350  -2.778  1.00 54.72  ? 127 SER I CB  1 
ATOM   2488 O OG  . SER B 1 127 ? 15.700  26.941  -2.830  1.00 60.02  ? 127 SER I OG  1 
ATOM   2489 N N   . SER B 1 128 ? 14.086  29.687  -0.843  1.00 55.04  ? 128 SER I N   1 
ATOM   2490 C CA  . SER B 1 128 ? 12.860  29.756  -0.059  1.00 54.47  ? 128 SER I CA  1 
ATOM   2491 C C   . SER B 1 128 ? 12.169  28.402  0.013   1.00 52.76  ? 128 SER I C   1 
ATOM   2492 O O   . SER B 1 128 ? 11.385  28.164  0.938   1.00 53.58  ? 128 SER I O   1 
ATOM   2493 C CB  . SER B 1 128 ? 11.912  30.798  -0.652  1.00 55.52  ? 128 SER I CB  1 
ATOM   2494 O OG  . SER B 1 128 ? 11.542  30.451  -1.975  1.00 54.39  ? 128 SER I OG  1 
ATOM   2495 N N   . LYS B 1 129 ? 12.449  27.513  -0.941  1.00 51.50  ? 129 LYS I N   1 
ATOM   2496 C CA  . LYS B 1 129 ? 11.904  26.164  -0.939  1.00 49.25  ? 129 LYS I CA  1 
ATOM   2497 C C   . LYS B 1 129 ? 12.618  25.243  0.041   1.00 49.44  ? 129 LYS I C   1 
ATOM   2498 O O   . LYS B 1 129 ? 12.106  24.155  0.327   1.00 38.55  ? 129 LYS I O   1 
ATOM   2499 C CB  . LYS B 1 129 ? 11.979  25.567  -2.347  1.00 46.59  ? 129 LYS I CB  1 
ATOM   2500 C CG  . LYS B 1 129 ? 11.707  26.561  -3.469  1.00 53.11  ? 129 LYS I CG  1 
ATOM   2501 C CD  . LYS B 1 129 ? 10.294  27.117  -3.408  1.00 59.46  ? 129 LYS I CD  1 
ATOM   2502 C CE  . LYS B 1 129 ? 10.017  28.028  -4.591  1.00 61.14  ? 129 LYS I CE  1 
ATOM   2503 N NZ  . LYS B 1 129 ? 8.616   28.526  -4.589  1.00 59.63  ? 129 LYS I NZ  1 
ATOM   2504 N N   . SER B 1 130 ? 13.785  25.642  0.549   1.00 51.45  ? 130 SER I N   1 
ATOM   2505 C CA  . SER B 1 130 ? 14.503  24.892  1.572   1.00 50.22  ? 130 SER I CA  1 
ATOM   2506 C C   . SER B 1 130 ? 14.728  25.745  2.816   1.00 55.04  ? 130 SER I C   1 
ATOM   2507 O O   . SER B 1 130 ? 15.726  25.583  3.522   1.00 54.18  ? 130 SER I O   1 
ATOM   2508 C CB  . SER B 1 130 ? 15.832  24.363  1.034   1.00 48.10  ? 130 SER I CB  1 
ATOM   2509 O OG  . SER B 1 130 ? 16.787  25.402  0.916   1.00 54.88  ? 130 SER I OG  1 
ATOM   2510 N N   . THR B 1 131 ? 13.810  26.669  3.084   1.00 56.80  ? 131 THR I N   1 
ATOM   2511 C CA  . THR B 1 131 ? 13.835  27.498  4.280   1.00 54.28  ? 131 THR I CA  1 
ATOM   2512 C C   . THR B 1 131 ? 12.576  27.222  5.089   1.00 64.65  ? 131 THR I C   1 
ATOM   2513 O O   . THR B 1 131 ? 11.462  27.318  4.564   1.00 68.19  ? 131 THR I O   1 
ATOM   2514 C CB  . THR B 1 131 ? 13.930  28.988  3.927   1.00 60.59  ? 131 THR I CB  1 
ATOM   2515 O OG1 . THR B 1 131 ? 15.289  29.324  3.621   1.00 57.29  ? 131 THR I OG1 1 
ATOM   2516 C CG2 . THR B 1 131 ? 13.443  29.851  5.085   1.00 65.45  ? 131 THR I CG2 1 
ATOM   2517 N N   . SER B 1 132 ? 12.758  26.869  6.361   1.00 67.84  ? 132 SER I N   1 
ATOM   2518 C CA  . SER B 1 132 ? 11.654  26.573  7.274   1.00 65.51  ? 132 SER I CA  1 
ATOM   2519 C C   . SER B 1 132 ? 11.854  27.425  8.524   1.00 66.94  ? 132 SER I C   1 
ATOM   2520 O O   . SER B 1 132 ? 12.540  27.014  9.464   1.00 64.18  ? 132 SER I O   1 
ATOM   2521 C CB  . SER B 1 132 ? 11.594  25.084  7.603   1.00 64.24  ? 132 SER I CB  1 
ATOM   2522 O OG  . SER B 1 132 ? 10.448  24.780  8.378   1.00 77.38  ? 132 SER I OG  1 
ATOM   2523 N N   . GLY B 1 133 ? 11.255  28.610  8.530   1.00 64.18  ? 133 GLY I N   1 
ATOM   2524 C CA  . GLY B 1 133 ? 11.426  29.505  9.664   1.00 67.66  ? 133 GLY I CA  1 
ATOM   2525 C C   . GLY B 1 133 ? 12.809  30.124  9.648   1.00 68.84  ? 133 GLY I C   1 
ATOM   2526 O O   . GLY B 1 133 ? 13.230  30.736  8.661   1.00 71.49  ? 133 GLY I O   1 
ATOM   2527 N N   . GLY B 1 134 ? 13.529  29.967  10.754  1.00 56.08  ? 134 GLY I N   1 
ATOM   2528 C CA  . GLY B 1 134 ? 14.883  30.458  10.883  1.00 52.56  ? 134 GLY I CA  1 
ATOM   2529 C C   . GLY B 1 134 ? 15.961  29.473  10.489  1.00 49.67  ? 134 GLY I C   1 
ATOM   2530 O O   . GLY B 1 134 ? 17.148  29.772  10.658  1.00 45.36  ? 134 GLY I O   1 
ATOM   2531 N N   . THR B 1 135 ? 15.588  28.306  9.972   1.00 50.26  ? 135 THR I N   1 
ATOM   2532 C CA  . THR B 1 135 ? 16.532  27.261  9.600   1.00 44.27  ? 135 THR I CA  1 
ATOM   2533 C C   . THR B 1 135 ? 16.510  27.042  8.093   1.00 48.22  ? 135 THR I C   1 
ATOM   2534 O O   . THR B 1 135 ? 15.445  26.815  7.509   1.00 51.20  ? 135 THR I O   1 
ATOM   2535 C CB  . THR B 1 135 ? 16.208  25.950  10.320  1.00 45.28  ? 135 THR I CB  1 
ATOM   2536 O OG1 . THR B 1 135 ? 16.302  26.142  11.736  1.00 52.38  ? 135 THR I OG1 1 
ATOM   2537 C CG2 . THR B 1 135 ? 17.173  24.854  9.895   1.00 40.97  ? 135 THR I CG2 1 
ATOM   2538 N N   . ALA B 1 136 ? 17.682  27.118  7.472   1.00 41.49  ? 136 ALA I N   1 
ATOM   2539 C CA  . ALA B 1 136 ? 17.857  26.802  6.064   1.00 42.00  ? 136 ALA I CA  1 
ATOM   2540 C C   . ALA B 1 136 ? 18.678  25.526  5.938   1.00 41.04  ? 136 ALA I C   1 
ATOM   2541 O O   . ALA B 1 136 ? 19.442  25.172  6.838   1.00 39.78  ? 136 ALA I O   1 
ATOM   2542 C CB  . ALA B 1 136 ? 18.545  27.948  5.315   1.00 41.83  ? 136 ALA I CB  1 
ATOM   2543 N N   . ALA B 1 137 ? 18.499  24.823  4.826   1.00 42.81  ? 137 ALA I N   1 
ATOM   2544 C CA  . ALA B 1 137 ? 19.244  23.604  4.547   1.00 36.99  ? 137 ALA I CA  1 
ATOM   2545 C C   . ALA B 1 137 ? 19.995  23.752  3.234   1.00 38.60  ? 137 ALA I C   1 
ATOM   2546 O O   . ALA B 1 137 ? 19.471  24.319  2.270   1.00 31.27  ? 137 ALA I O   1 
ATOM   2547 C CB  . ALA B 1 137 ? 18.318  22.386  4.486   1.00 35.26  ? 137 ALA I CB  1 
ATOM   2548 N N   . LEU B 1 138 ? 21.226  23.240  3.197   1.00 33.52  ? 138 LEU I N   1 
ATOM   2549 C CA  . LEU B 1 138 ? 22.018  23.235  1.972   1.00 39.02  ? 138 LEU I CA  1 
ATOM   2550 C C   . LEU B 1 138 ? 22.831  21.949  1.938   1.00 37.54  ? 138 LEU I C   1 
ATOM   2551 O O   . LEU B 1 138 ? 22.794  21.151  2.877   1.00 37.93  ? 138 LEU I O   1 
ATOM   2552 C CB  . LEU B 1 138 ? 22.909  24.482  1.876   1.00 35.28  ? 138 LEU I CB  1 
ATOM   2553 C CG  . LEU B 1 138 ? 23.830  24.842  3.045   1.00 36.99  ? 138 LEU I CG  1 
ATOM   2554 C CD1 . LEU B 1 138 ? 25.191  24.172  2.898   1.00 32.97  ? 138 LEU I CD1 1 
ATOM   2555 C CD2 . LEU B 1 138 ? 23.980  26.348  3.176   1.00 40.12  ? 138 LEU I CD2 1 
ATOM   2556 N N   . GLY B 1 139 ? 23.544  21.721  0.843   1.00 32.82  ? 139 GLY I N   1 
ATOM   2557 C CA  . GLY B 1 139 ? 24.371  20.531  0.775   1.00 35.94  ? 139 GLY I CA  1 
ATOM   2558 C C   . GLY B 1 139 ? 25.065  20.336  -0.554  1.00 37.87  ? 139 GLY I C   1 
ATOM   2559 O O   . GLY B 1 139 ? 25.192  21.259  -1.360  1.00 37.59  ? 139 GLY I O   1 
ATOM   2560 N N   . CYS B 1 140 ? 25.507  19.098  -0.765  1.00 36.82  ? 140 CYS I N   1 
ATOM   2561 C CA  . CYS B 1 140 ? 26.230  18.693  -1.960  1.00 36.22  ? 140 CYS I CA  1 
ATOM   2562 C C   . CYS B 1 140 ? 25.778  17.307  -2.398  1.00 34.54  ? 140 CYS I C   1 
ATOM   2563 O O   . CYS B 1 140 ? 25.596  16.408  -1.571  1.00 33.45  ? 140 CYS I O   1 
ATOM   2564 C CB  . CYS B 1 140 ? 27.748  18.701  -1.725  1.00 34.38  ? 140 CYS I CB  1 
ATOM   2565 S SG  . CYS B 1 140 ? 28.479  20.353  -1.715  1.00 52.19  ? 140 CYS I SG  1 
ATOM   2566 N N   . LEU B 1 141 ? 25.598  17.148  -3.707  1.00 37.49  ? 141 LEU I N   1 
ATOM   2567 C CA  . LEU B 1 141 ? 25.264  15.873  -4.326  1.00 38.40  ? 141 LEU I CA  1 
ATOM   2568 C C   . LEU B 1 141 ? 26.514  15.297  -4.977  1.00 34.53  ? 141 LEU I C   1 
ATOM   2569 O O   . LEU B 1 141 ? 27.078  15.906  -5.893  1.00 34.62  ? 141 LEU I O   1 
ATOM   2570 C CB  . LEU B 1 141 ? 24.154  16.047  -5.362  1.00 31.10  ? 141 LEU I CB  1 
ATOM   2571 C CG  . LEU B 1 141 ? 23.712  14.789  -6.112  1.00 37.30  ? 141 LEU I CG  1 
ATOM   2572 C CD1 . LEU B 1 141 ? 23.096  13.777  -5.160  1.00 35.62  ? 141 LEU I CD1 1 
ATOM   2573 C CD2 . LEU B 1 141 ? 22.745  15.142  -7.231  1.00 36.35  ? 141 LEU I CD2 1 
ATOM   2574 N N   . VAL B 1 142 ? 26.946  14.136  -4.498  1.00 33.71  ? 142 VAL I N   1 
ATOM   2575 C CA  . VAL B 1 142 ? 28.138  13.449  -4.982  1.00 30.67  ? 142 VAL I CA  1 
ATOM   2576 C C   . VAL B 1 142 ? 27.648  12.278  -5.826  1.00 30.38  ? 142 VAL I C   1 
ATOM   2577 O O   . VAL B 1 142 ? 27.199  11.261  -5.285  1.00 31.53  ? 142 VAL I O   1 
ATOM   2578 C CB  . VAL B 1 142 ? 29.026  12.981  -3.823  1.00 32.74  ? 142 VAL I CB  1 
ATOM   2579 C CG1 . VAL B 1 142 ? 30.322  12.396  -4.338  1.00 34.74  ? 142 VAL I CG1 1 
ATOM   2580 C CG2 . VAL B 1 142 ? 29.294  14.133  -2.863  1.00 31.33  ? 142 VAL I CG2 1 
ATOM   2581 N N   . LYS B 1 143 ? 27.723  12.408  -7.152  1.00 37.09  ? 143 LYS I N   1 
ATOM   2582 C CA  . LYS B 1 143 ? 27.026  11.508  -8.061  1.00 33.78  ? 143 LYS I CA  1 
ATOM   2583 C C   . LYS B 1 143 ? 27.998  10.829  -9.017  1.00 37.39  ? 143 LYS I C   1 
ATOM   2584 O O   . LYS B 1 143 ? 29.012  11.414  -9.414  1.00 40.26  ? 143 LYS I O   1 
ATOM   2585 C CB  . LYS B 1 143 ? 25.969  12.260  -8.882  1.00 39.23  ? 143 LYS I CB  1 
ATOM   2586 C CG  . LYS B 1 143 ? 24.944  11.356  -9.550  1.00 39.70  ? 143 LYS I CG  1 
ATOM   2587 C CD  . LYS B 1 143 ? 23.713  12.140  -9.979  1.00 42.66  ? 143 LYS I CD  1 
ATOM   2588 C CE  . LYS B 1 143 ? 22.926  11.405  -11.057 1.00 36.03  ? 143 LYS I CE  1 
ATOM   2589 N NZ  . LYS B 1 143 ? 23.795  10.767  -12.086 1.00 48.62  ? 143 LYS I NZ  1 
ATOM   2590 N N   . ASP B 1 144 ? 27.676  9.580   -9.374  1.00 38.11  ? 144 ASP I N   1 
ATOM   2591 C CA  . ASP B 1 144 ? 28.323  8.864   -10.468 1.00 36.16  ? 144 ASP I CA  1 
ATOM   2592 C C   . ASP B 1 144 ? 29.800  8.608   -10.205 1.00 39.06  ? 144 ASP I C   1 
ATOM   2593 O O   . ASP B 1 144 ? 30.656  9.041   -10.983 1.00 43.68  ? 144 ASP I O   1 
ATOM   2594 C CB  . ASP B 1 144 ? 28.137  9.627   -11.778 1.00 38.27  ? 144 ASP I CB  1 
ATOM   2595 C CG  . ASP B 1 144 ? 26.679  9.742   -12.176 1.00 46.70  ? 144 ASP I CG  1 
ATOM   2596 O OD1 . ASP B 1 144 ? 25.871  8.907   -11.722 1.00 39.22  ? 144 ASP I OD1 1 
ATOM   2597 O OD2 . ASP B 1 144 ? 26.340  10.670  -12.935 1.00 39.60  ? 144 ASP I OD2 1 
ATOM   2598 N N   . TYR B 1 145 ? 30.105  7.906   -9.117  1.00 33.46  ? 145 TYR I N   1 
ATOM   2599 C CA  . TYR B 1 145 ? 31.462  7.494   -8.802  1.00 34.76  ? 145 TYR I CA  1 
ATOM   2600 C C   . TYR B 1 145 ? 31.485  5.998   -8.527  1.00 36.04  ? 145 TYR I C   1 
ATOM   2601 O O   . TYR B 1 145 ? 30.453  5.374   -8.266  1.00 33.99  ? 145 TYR I O   1 
ATOM   2602 C CB  . TYR B 1 145 ? 32.025  8.264   -7.599  1.00 36.14  ? 145 TYR I CB  1 
ATOM   2603 C CG  . TYR B 1 145 ? 31.311  8.002   -6.289  1.00 35.56  ? 145 TYR I CG  1 
ATOM   2604 C CD1 . TYR B 1 145 ? 31.708  6.968   -5.450  1.00 35.22  ? 145 TYR I CD1 1 
ATOM   2605 C CD2 . TYR B 1 145 ? 30.243  8.794   -5.890  1.00 34.88  ? 145 TYR I CD2 1 
ATOM   2606 C CE1 . TYR B 1 145 ? 31.057  6.728   -4.253  1.00 36.11  ? 145 TYR I CE1 1 
ATOM   2607 C CE2 . TYR B 1 145 ? 29.587  8.562   -4.695  1.00 36.63  ? 145 TYR I CE2 1 
ATOM   2608 C CZ  . TYR B 1 145 ? 29.999  7.527   -3.881  1.00 38.51  ? 145 TYR I CZ  1 
ATOM   2609 O OH  . TYR B 1 145 ? 29.350  7.293   -2.691  1.00 34.30  ? 145 TYR I OH  1 
ATOM   2610 N N   . PHE B 1 146 ? 32.691  5.429   -8.587  1.00 38.16  ? 146 PHE I N   1 
ATOM   2611 C CA  . PHE B 1 146 ? 32.908  4.024   -8.276  1.00 35.53  ? 146 PHE I CA  1 
ATOM   2612 C C   . PHE B 1 146 ? 34.388  3.825   -8.006  1.00 34.75  ? 146 PHE I C   1 
ATOM   2613 O O   . PHE B 1 146 ? 35.215  4.427   -8.705  1.00 41.08  ? 146 PHE I O   1 
ATOM   2614 C CB  . PHE B 1 146 ? 32.447  3.112   -9.420  1.00 34.36  ? 146 PHE I CB  1 
ATOM   2615 C CG  . PHE B 1 146 ? 32.535  1.643   -9.100  1.00 34.37  ? 146 PHE I CG  1 
ATOM   2616 C CD1 . PHE B 1 146 ? 31.473  0.984   -8.500  1.00 34.36  ? 146 PHE I CD1 1 
ATOM   2617 C CD2 . PHE B 1 146 ? 33.680  0.921   -9.400  1.00 37.74  ? 146 PHE I CD2 1 
ATOM   2618 C CE1 . PHE B 1 146 ? 31.554  -0.364  -8.204  1.00 35.44  ? 146 PHE I CE1 1 
ATOM   2619 C CE2 . PHE B 1 146 ? 33.765  -0.428  -9.106  1.00 37.27  ? 146 PHE I CE2 1 
ATOM   2620 C CZ  . PHE B 1 146 ? 32.700  -1.071  -8.509  1.00 34.03  ? 146 PHE I CZ  1 
ATOM   2621 N N   . PRO B 1 147 ? 34.761  3.011   -7.014  1.00 35.96  ? 147 PRO I N   1 
ATOM   2622 C CA  . PRO B 1 147 ? 33.896  2.327   -6.047  1.00 35.87  ? 147 PRO I CA  1 
ATOM   2623 C C   . PRO B 1 147 ? 33.714  3.138   -4.771  1.00 36.93  ? 147 PRO I C   1 
ATOM   2624 O O   . PRO B 1 147 ? 34.152  4.284   -4.683  1.00 37.01  ? 147 PRO I O   1 
ATOM   2625 C CB  . PRO B 1 147 ? 34.660  1.024   -5.791  1.00 35.37  ? 147 PRO I CB  1 
ATOM   2626 C CG  . PRO B 1 147 ? 36.104  1.461   -5.848  1.00 38.56  ? 147 PRO I CG  1 
ATOM   2627 C CD  . PRO B 1 147 ? 36.159  2.556   -6.900  1.00 37.81  ? 147 PRO I CD  1 
ATOM   2628 N N   . GLU B 1 148 ? 33.061  2.560   -3.765  1.00 34.38  ? 148 GLU I N   1 
ATOM   2629 C CA  . GLU B 1 148 ? 33.033  3.163   -2.447  1.00 35.35  ? 148 GLU I CA  1 
ATOM   2630 C C   . GLU B 1 148 ? 34.437  3.158   -1.847  1.00 37.46  ? 148 GLU I C   1 
ATOM   2631 O O   . GLU B 1 148 ? 35.275  2.328   -2.208  1.00 37.08  ? 148 GLU I O   1 
ATOM   2632 C CB  . GLU B 1 148 ? 32.064  2.409   -1.535  1.00 38.48  ? 148 GLU I CB  1 
ATOM   2633 C CG  . GLU B 1 148 ? 30.589  2.689   -1.790  1.00 38.51  ? 148 GLU I CG  1 
ATOM   2634 C CD  . GLU B 1 148 ? 30.054  3.824   -0.930  1.00 45.16  ? 148 GLU I CD  1 
ATOM   2635 O OE1 . GLU B 1 148 ? 30.581  4.951   -1.034  1.00 43.27  ? 148 GLU I OE1 1 
ATOM   2636 O OE2 . GLU B 1 148 ? 29.110  3.587   -0.146  1.00 43.27  ? 148 GLU I OE2 1 
ATOM   2637 N N   . PRO B 1 149 ? 34.725  4.087   -0.928  1.00 36.94  ? 149 PRO I N   1 
ATOM   2638 C CA  . PRO B 1 149 ? 33.856  5.160   -0.444  1.00 36.66  ? 149 PRO I CA  1 
ATOM   2639 C C   . PRO B 1 149 ? 34.327  6.550   -0.850  1.00 37.06  ? 149 PRO I C   1 
ATOM   2640 O O   . PRO B 1 149 ? 35.401  6.720   -1.421  1.00 36.30  ? 149 PRO I O   1 
ATOM   2641 C CB  . PRO B 1 149 ? 33.940  4.969   1.070   1.00 37.92  ? 149 PRO I CB  1 
ATOM   2642 C CG  . PRO B 1 149 ? 35.407  4.621   1.269   1.00 36.02  ? 149 PRO I CG  1 
ATOM   2643 C CD  . PRO B 1 149 ? 35.834  3.860   0.016   1.00 32.11  ? 149 PRO I CD  1 
ATOM   2644 N N   . VAL B 1 150 ? 33.519  7.566   -0.562  1.00 32.79  ? 150 VAL I N   1 
ATOM   2645 C CA  . VAL B 1 150 ? 33.967  8.949   -0.577  1.00 35.82  ? 150 VAL I CA  1 
ATOM   2646 C C   . VAL B 1 150 ? 33.833  9.483   0.841   1.00 37.22  ? 150 VAL I C   1 
ATOM   2647 O O   . VAL B 1 150 ? 33.078  8.956   1.662   1.00 29.73  ? 150 VAL I O   1 
ATOM   2648 C CB  . VAL B 1 150 ? 33.180  9.830   -1.571  1.00 33.76  ? 150 VAL I CB  1 
ATOM   2649 C CG1 . VAL B 1 150 ? 33.206  9.222   -2.962  1.00 35.47  ? 150 VAL I CG1 1 
ATOM   2650 C CG2 . VAL B 1 150 ? 31.753  10.030  -1.097  1.00 35.72  ? 150 VAL I CG2 1 
ATOM   2651 N N   . THR B 1 151 ? 34.583  10.540  1.127   1.00 35.80  ? 151 THR I N   1 
ATOM   2652 C CA  . THR B 1 151 ? 34.480  11.242  2.396   1.00 35.21  ? 151 THR I CA  1 
ATOM   2653 C C   . THR B 1 151 ? 34.050  12.677  2.135   1.00 35.96  ? 151 THR I C   1 
ATOM   2654 O O   . THR B 1 151 ? 34.461  13.286  1.144   1.00 34.89  ? 151 THR I O   1 
ATOM   2655 C CB  . THR B 1 151 ? 35.808  11.218  3.161   1.00 36.54  ? 151 THR I CB  1 
ATOM   2656 O OG1 . THR B 1 151 ? 36.830  11.835  2.370   1.00 39.43  ? 151 THR I OG1 1 
ATOM   2657 C CG2 . THR B 1 151 ? 36.213  9.786   3.478   1.00 38.89  ? 151 THR I CG2 1 
ATOM   2658 N N   . VAL B 1 152 ? 33.213  13.210  3.021   1.00 35.35  ? 152 VAL I N   1 
ATOM   2659 C CA  . VAL B 1 152 ? 32.698  14.567  2.892   1.00 38.14  ? 152 VAL I CA  1 
ATOM   2660 C C   . VAL B 1 152 ? 32.918  15.301  4.205   1.00 38.74  ? 152 VAL I C   1 
ATOM   2661 O O   . VAL B 1 152 ? 32.560  14.794  5.274   1.00 35.31  ? 152 VAL I O   1 
ATOM   2662 C CB  . VAL B 1 152 ? 31.203  14.585  2.515   1.00 37.55  ? 152 VAL I CB  1 
ATOM   2663 C CG1 . VAL B 1 152 ? 30.748  16.008  2.232   1.00 33.62  ? 152 VAL I CG1 1 
ATOM   2664 C CG2 . VAL B 1 152 ? 30.935  13.685  1.316   1.00 33.21  ? 152 VAL I CG2 1 
ATOM   2665 N N   . SER B 1 153 ? 33.511  16.485  4.123   1.00 37.06  ? 153 SER I N   1 
ATOM   2666 C CA  . SER B 1 153 ? 33.596  17.407  5.245   1.00 34.25  ? 153 SER I CA  1 
ATOM   2667 C C   . SER B 1 153 ? 32.997  18.743  4.827   1.00 37.29  ? 153 SER I C   1 
ATOM   2668 O O   . SER B 1 153 ? 32.705  18.976  3.653   1.00 37.29  ? 153 SER I O   1 
ATOM   2669 C CB  . SER B 1 153 ? 35.045  17.588  5.718   1.00 35.33  ? 153 SER I CB  1 
ATOM   2670 O OG  . SER B 1 153 ? 35.829  18.241  4.736   1.00 39.39  ? 153 SER I OG  1 
ATOM   2671 N N   . TRP B 1 154 ? 32.809  19.631  5.798   1.00 34.90  ? 154 TRP I N   1 
ATOM   2672 C CA  . TRP B 1 154 ? 32.253  20.950  5.527   1.00 32.50  ? 154 TRP I CA  1 
ATOM   2673 C C   . TRP B 1 154 ? 33.151  22.019  6.128   1.00 36.42  ? 154 TRP I C   1 
ATOM   2674 O O   . TRP B 1 154 ? 33.504  21.947  7.310   1.00 35.43  ? 154 TRP I O   1 
ATOM   2675 C CB  . TRP B 1 154 ? 30.825  21.074  6.067   1.00 34.02  ? 154 TRP I CB  1 
ATOM   2676 C CG  . TRP B 1 154 ? 29.818  20.410  5.178   1.00 36.49  ? 154 TRP I CG  1 
ATOM   2677 C CD1 . TRP B 1 154 ? 29.349  19.132  5.276   1.00 32.22  ? 154 TRP I CD1 1 
ATOM   2678 C CD2 . TRP B 1 154 ? 29.172  20.987  4.036   1.00 32.72  ? 154 TRP I CD2 1 
ATOM   2679 N NE1 . TRP B 1 154 ? 28.443  18.882  4.273   1.00 35.09  ? 154 TRP I NE1 1 
ATOM   2680 C CE2 . TRP B 1 154 ? 28.318  20.005  3.498   1.00 35.07  ? 154 TRP I CE2 1 
ATOM   2681 C CE3 . TRP B 1 154 ? 29.230  22.241  3.420   1.00 35.14  ? 154 TRP I CE3 1 
ATOM   2682 C CZ2 . TRP B 1 154 ? 27.528  20.238  2.375   1.00 36.76  ? 154 TRP I CZ2 1 
ATOM   2683 C CZ3 . TRP B 1 154 ? 28.446  22.470  2.304   1.00 34.16  ? 154 TRP I CZ3 1 
ATOM   2684 C CH2 . TRP B 1 154 ? 27.606  21.474  1.793   1.00 33.82  ? 154 TRP I CH2 1 
ATOM   2685 N N   . ASN B 1 155 ? 33.503  23.012  5.309   1.00 38.12  ? 155 ASN I N   1 
ATOM   2686 C CA  . ASN B 1 155 ? 34.393  24.105  5.699   1.00 38.56  ? 155 ASN I CA  1 
ATOM   2687 C C   . ASN B 1 155 ? 35.685  23.575  6.319   1.00 37.30  ? 155 ASN I C   1 
ATOM   2688 O O   . ASN B 1 155 ? 36.156  24.058  7.350   1.00 40.10  ? 155 ASN I O   1 
ATOM   2689 C CB  . ASN B 1 155 ? 33.682  25.076  6.641   1.00 34.11  ? 155 ASN I CB  1 
ATOM   2690 C CG  . ASN B 1 155 ? 32.508  25.770  5.981   1.00 39.49  ? 155 ASN I CG  1 
ATOM   2691 O OD1 . ASN B 1 155 ? 32.310  25.665  4.771   1.00 42.75  ? 155 ASN I OD1 1 
ATOM   2692 N ND2 . ASN B 1 155 ? 31.724  26.492  6.774   1.00 35.49  ? 155 ASN I ND2 1 
ATOM   2693 N N   . SER B 1 156 ? 36.259  22.561  5.666   1.00 35.43  ? 156 SER I N   1 
ATOM   2694 C CA  . SER B 1 156 ? 37.524  21.950  6.077   1.00 37.11  ? 156 SER I CA  1 
ATOM   2695 C C   . SER B 1 156 ? 37.468  21.415  7.506   1.00 40.55  ? 156 SER I C   1 
ATOM   2696 O O   . SER B 1 156 ? 38.480  21.388  8.210   1.00 46.56  ? 156 SER I O   1 
ATOM   2697 C CB  . SER B 1 156 ? 38.690  22.931  5.916   1.00 42.70  ? 156 SER I CB  1 
ATOM   2698 O OG  . SER B 1 156 ? 38.829  23.336  4.566   1.00 43.68  ? 156 SER I OG  1 
ATOM   2699 N N   . GLY B 1 157 ? 36.286  20.988  7.946   1.00 41.51  ? 157 GLY I N   1 
ATOM   2700 C CA  . GLY B 1 157 ? 36.105  20.425  9.266   1.00 38.52  ? 157 GLY I CA  1 
ATOM   2701 C C   . GLY B 1 157 ? 35.569  21.388  10.304  1.00 36.11  ? 157 GLY I C   1 
ATOM   2702 O O   . GLY B 1 157 ? 35.196  20.945  11.399  1.00 44.38  ? 157 GLY I O   1 
ATOM   2703 N N   . ALA B 1 158 ? 35.517  22.686  9.997   1.00 38.15  ? 158 ALA I N   1 
ATOM   2704 C CA  . ALA B 1 158 ? 35.048  23.665  10.970  1.00 36.03  ? 158 ALA I CA  1 
ATOM   2705 C C   . ALA B 1 158 ? 33.542  23.597  11.183  1.00 40.09  ? 158 ALA I C   1 
ATOM   2706 O O   . ALA B 1 158 ? 33.050  24.105  12.196  1.00 43.72  ? 158 ALA I O   1 
ATOM   2707 C CB  . ALA B 1 158 ? 35.452  25.074  10.535  1.00 34.72  ? 158 ALA I CB  1 
ATOM   2708 N N   . LEU B 1 159 ? 32.803  22.988  10.258  1.00 37.38  ? 159 LEU I N   1 
ATOM   2709 C CA  . LEU B 1 159 ? 31.353  22.865  10.355  1.00 34.92  ? 159 LEU I CA  1 
ATOM   2710 C C   . LEU B 1 159 ? 31.006  21.385  10.454  1.00 41.24  ? 159 LEU I C   1 
ATOM   2711 O O   . LEU B 1 159 ? 31.182  20.635  9.488   1.00 35.88  ? 159 LEU I O   1 
ATOM   2712 C CB  . LEU B 1 159 ? 30.665  23.515  9.155   1.00 34.80  ? 159 LEU I CB  1 
ATOM   2713 C CG  . LEU B 1 159 ? 29.141  23.404  9.104   1.00 36.75  ? 159 LEU I CG  1 
ATOM   2714 C CD1 . LEU B 1 159 ? 28.515  24.017  10.349  1.00 34.10  ? 159 LEU I CD1 1 
ATOM   2715 C CD2 . LEU B 1 159 ? 28.605  24.071  7.851   1.00 33.85  ? 159 LEU I CD2 1 
ATOM   2716 N N   . THR B 1 160 ? 30.514  20.970  11.619  1.00 35.01  ? 160 THR I N   1 
ATOM   2717 C CA  . THR B 1 160 ? 30.136  19.581  11.849  1.00 35.95  ? 160 THR I CA  1 
ATOM   2718 C C   . THR B 1 160 ? 28.706  19.497  12.365  1.00 39.68  ? 160 THR I C   1 
ATOM   2719 O O   . THR B 1 160 ? 28.012  18.502  12.136  1.00 37.35  ? 160 THR I O   1 
ATOM   2720 C CB  . THR B 1 160 ? 31.090  18.916  12.845  1.00 38.70  ? 160 THR I CB  1 
ATOM   2721 O OG1 . THR B 1 160 ? 31.088  19.655  14.074  1.00 37.19  ? 160 THR I OG1 1 
ATOM   2722 C CG2 . THR B 1 160 ? 32.506  18.872  12.289  1.00 36.79  ? 160 THR I CG2 1 
ATOM   2723 N N   . SER B 1 161 ? 28.264  20.539  13.064  1.00 35.82  ? 161 SER I N   1 
ATOM   2724 C CA  . SER B 1 161 ? 26.938  20.536  13.665  1.00 39.10  ? 161 SER I CA  1 
ATOM   2725 C C   . SER B 1 161 ? 25.860  20.621  12.591  1.00 36.39  ? 161 SER I C   1 
ATOM   2726 O O   . SER B 1 161 ? 25.912  21.483  11.707  1.00 39.69  ? 161 SER I O   1 
ATOM   2727 C CB  . SER B 1 161 ? 26.804  21.700  14.645  1.00 35.72  ? 161 SER I CB  1 
ATOM   2728 O OG  . SER B 1 161 ? 25.599  21.611  15.384  1.00 43.92  ? 161 SER I OG  1 
ATOM   2729 N N   . GLY B 1 162 ? 24.883  19.720  12.669  1.00 38.05  ? 162 GLY I N   1 
ATOM   2730 C CA  . GLY B 1 162 ? 23.799  19.689  11.710  1.00 38.61  ? 162 GLY I CA  1 
ATOM   2731 C C   . GLY B 1 162 ? 24.104  18.981  10.411  1.00 38.22  ? 162 GLY I C   1 
ATOM   2732 O O   . GLY B 1 162 ? 23.267  19.003  9.503   1.00 30.97  ? 162 GLY I O   1 
ATOM   2733 N N   . VAL B 1 163 ? 25.265  18.348  10.293  1.00 35.71  ? 163 VAL I N   1 
ATOM   2734 C CA  . VAL B 1 163 ? 25.670  17.681  9.061   1.00 34.79  ? 163 VAL I CA  1 
ATOM   2735 C C   . VAL B 1 163 ? 25.111  16.265  9.046   1.00 37.75  ? 163 VAL I C   1 
ATOM   2736 O O   . VAL B 1 163 ? 25.255  15.516  10.019  1.00 35.39  ? 163 VAL I O   1 
ATOM   2737 C CB  . VAL B 1 163 ? 27.201  17.671  8.920   1.00 31.09  ? 163 VAL I CB  1 
ATOM   2738 C CG1 . VAL B 1 163 ? 27.620  16.853  7.709   1.00 32.92  ? 163 VAL I CG1 1 
ATOM   2739 C CG2 . VAL B 1 163 ? 27.730  19.093  8.815   1.00 35.38  ? 163 VAL I CG2 1 
ATOM   2740 N N   . HIS B 1 164 ? 24.475  15.900  7.934   1.00 34.15  ? 164 HIS I N   1 
ATOM   2741 C CA  . HIS B 1 164 ? 24.023  14.536  7.676   1.00 34.91  ? 164 HIS I CA  1 
ATOM   2742 C C   . HIS B 1 164 ? 24.592  14.116  6.329   1.00 36.94  ? 164 HIS I C   1 
ATOM   2743 O O   . HIS B 1 164 ? 24.172  14.632  5.289   1.00 31.60  ? 164 HIS I O   1 
ATOM   2744 C CB  . HIS B 1 164 ? 22.496  14.441  7.658   1.00 34.85  ? 164 HIS I CB  1 
ATOM   2745 C CG  . HIS B 1 164 ? 21.848  14.680  8.986   1.00 36.44  ? 164 HIS I CG  1 
ATOM   2746 N ND1 . HIS B 1 164 ? 22.029  13.844  10.066  1.00 36.28  ? 164 HIS I ND1 1 
ATOM   2747 C CD2 . HIS B 1 164 ? 20.999  15.650  9.401   1.00 35.01  ? 164 HIS I CD2 1 
ATOM   2748 C CE1 . HIS B 1 164 ? 21.333  14.297  11.094  1.00 36.12  ? 164 HIS I CE1 1 
ATOM   2749 N NE2 . HIS B 1 164 ? 20.698  15.391  10.716  1.00 35.28  ? 164 HIS I NE2 1 
ATOM   2750 N N   . THR B 1 165 ? 25.542  13.188  6.340   1.00 35.32  ? 165 THR I N   1 
ATOM   2751 C CA  . THR B 1 165 ? 26.072  12.604  5.114   1.00 30.85  ? 165 THR I CA  1 
ATOM   2752 C C   . THR B 1 165 ? 25.420  11.237  4.946   1.00 36.55  ? 165 THR I C   1 
ATOM   2753 O O   . THR B 1 165 ? 25.689  10.313  5.721   1.00 39.23  ? 165 THR I O   1 
ATOM   2754 C CB  . THR B 1 165 ? 27.594  12.494  5.158   1.00 37.18  ? 165 THR I CB  1 
ATOM   2755 O OG1 . THR B 1 165 ? 28.166  13.806  5.224   1.00 33.92  ? 165 THR I OG1 1 
ATOM   2756 C CG2 . THR B 1 165 ? 28.110  11.788  3.912   1.00 32.34  ? 165 THR I CG2 1 
ATOM   2757 N N   . PHE B 1 166 ? 24.573  11.110  3.932   1.00 28.20  ? 166 PHE I N   1 
ATOM   2758 C CA  . PHE B 1 166 ? 23.732  9.932   3.818   1.00 34.17  ? 166 PHE I CA  1 
ATOM   2759 C C   . PHE B 1 166 ? 24.500  8.760   3.214   1.00 36.22  ? 166 PHE I C   1 
ATOM   2760 O O   . PHE B 1 166 ? 25.461  8.956   2.465   1.00 36.47  ? 166 PHE I O   1 
ATOM   2761 C CB  . PHE B 1 166 ? 22.506  10.237  2.964   1.00 34.85  ? 166 PHE I CB  1 
ATOM   2762 C CG  . PHE B 1 166 ? 21.496  11.104  3.650   1.00 34.72  ? 166 PHE I CG  1 
ATOM   2763 C CD1 . PHE B 1 166 ? 21.598  12.484  3.605   1.00 35.60  ? 166 PHE I CD1 1 
ATOM   2764 C CD2 . PHE B 1 166 ? 20.445  10.537  4.349   1.00 35.16  ? 166 PHE I CD2 1 
ATOM   2765 C CE1 . PHE B 1 166 ? 20.667  13.282  4.241   1.00 35.23  ? 166 PHE I CE1 1 
ATOM   2766 C CE2 . PHE B 1 166 ? 19.513  11.329  4.987   1.00 35.04  ? 166 PHE I CE2 1 
ATOM   2767 C CZ  . PHE B 1 166 ? 19.623  12.702  4.934   1.00 34.88  ? 166 PHE I CZ  1 
ATOM   2768 N N   . PRO B 1 167 ? 24.098  7.533   3.540   1.00 31.93  ? 167 PRO I N   1 
ATOM   2769 C CA  . PRO B 1 167 ? 24.670  6.367   2.858   1.00 32.85  ? 167 PRO I CA  1 
ATOM   2770 C C   . PRO B 1 167 ? 24.430  6.442   1.358   1.00 35.93  ? 167 PRO I C   1 
ATOM   2771 O O   . PRO B 1 167 ? 23.375  6.884   0.898   1.00 36.18  ? 167 PRO I O   1 
ATOM   2772 C CB  . PRO B 1 167 ? 23.926  5.185   3.492   1.00 32.59  ? 167 PRO I CB  1 
ATOM   2773 C CG  . PRO B 1 167 ? 23.463  5.695   4.819   1.00 32.04  ? 167 PRO I CG  1 
ATOM   2774 C CD  . PRO B 1 167 ? 23.164  7.149   4.613   1.00 28.30  ? 167 PRO I CD  1 
ATOM   2775 N N   . ALA B 1 168 ? 25.428  6.008   0.594   1.00 32.82  ? 168 ALA I N   1 
ATOM   2776 C CA  . ALA B 1 168 ? 25.304  6.007   -0.854  1.00 35.27  ? 168 ALA I CA  1 
ATOM   2777 C C   . ALA B 1 168 ? 24.295  4.959   -1.310  1.00 32.13  ? 168 ALA I C   1 
ATOM   2778 O O   . ALA B 1 168 ? 24.104  3.922   -0.669  1.00 34.37  ? 168 ALA I O   1 
ATOM   2779 C CB  . ALA B 1 168 ? 26.661  5.747   -1.506  1.00 33.79  ? 168 ALA I CB  1 
ATOM   2780 N N   . VAL B 1 169 ? 23.636  5.249   -2.428  1.00 36.21  ? 169 VAL I N   1 
ATOM   2781 C CA  . VAL B 1 169 ? 22.777  4.285   -3.101  1.00 34.25  ? 169 VAL I CA  1 
ATOM   2782 C C   . VAL B 1 169 ? 23.449  3.879   -4.403  1.00 34.40  ? 169 VAL I C   1 
ATOM   2783 O O   . VAL B 1 169 ? 24.175  4.662   -5.026  1.00 33.48  ? 169 VAL I O   1 
ATOM   2784 C CB  . VAL B 1 169 ? 21.360  4.840   -3.359  1.00 33.91  ? 169 VAL I CB  1 
ATOM   2785 C CG1 . VAL B 1 169 ? 20.697  5.233   -2.048  1.00 37.01  ? 169 VAL I CG1 1 
ATOM   2786 C CG2 . VAL B 1 169 ? 21.408  6.024   -4.318  1.00 31.56  ? 169 VAL I CG2 1 
ATOM   2787 N N   . LEU B 1 170 ? 23.215  2.634   -4.806  1.00 32.74  ? 170 LEU I N   1 
ATOM   2788 C CA  . LEU B 1 170 ? 23.726  2.119   -6.068  1.00 37.39  ? 170 LEU I CA  1 
ATOM   2789 C C   . LEU B 1 170 ? 22.688  2.353   -7.158  1.00 36.22  ? 170 LEU I C   1 
ATOM   2790 O O   . LEU B 1 170 ? 21.564  1.846   -7.072  1.00 33.07  ? 170 LEU I O   1 
ATOM   2791 C CB  . LEU B 1 170 ? 24.065  0.634   -5.953  1.00 34.82  ? 170 LEU I CB  1 
ATOM   2792 C CG  . LEU B 1 170 ? 24.574  -0.038  -7.228  1.00 36.84  ? 170 LEU I CG  1 
ATOM   2793 C CD1 . LEU B 1 170 ? 25.824  0.662   -7.743  1.00 33.97  ? 170 LEU I CD1 1 
ATOM   2794 C CD2 . LEU B 1 170 ? 24.849  -1.513  -6.982  1.00 31.77  ? 170 LEU I CD2 1 
ATOM   2795 N N   . GLN B 1 171 ? 23.062  3.122   -8.176  1.00 37.09  ? 171 GLN I N   1 
ATOM   2796 C CA  . GLN B 1 171 ? 22.160  3.413   -9.276  1.00 38.61  ? 171 GLN I CA  1 
ATOM   2797 C C   . GLN B 1 171 ? 22.167  2.267   -10.285 1.00 37.89  ? 171 GLN I C   1 
ATOM   2798 O O   . GLN B 1 171 ? 23.032  1.387   -10.265 1.00 38.70  ? 171 GLN I O   1 
ATOM   2799 C CB  . GLN B 1 171 ? 22.552  4.724   -9.955  1.00 35.47  ? 171 GLN I CB  1 
ATOM   2800 C CG  . GLN B 1 171 ? 22.589  5.922   -9.020  1.00 37.86  ? 171 GLN I CG  1 
ATOM   2801 C CD  . GLN B 1 171 ? 23.265  7.127   -9.643  1.00 42.01  ? 171 GLN I CD  1 
ATOM   2802 O OE1 . GLN B 1 171 ? 22.606  8.083   -10.052 1.00 49.05  ? 171 GLN I OE1 1 
ATOM   2803 N NE2 . GLN B 1 171 ? 24.591  7.090   -9.712  1.00 38.63  ? 171 GLN I NE2 1 
ATOM   2804 N N   . SER B 1 172 ? 21.178  2.287   -11.181 1.00 39.99  ? 172 SER I N   1 
ATOM   2805 C CA  . SER B 1 172 ? 21.089  1.262   -12.215 1.00 36.98  ? 172 SER I CA  1 
ATOM   2806 C C   . SER B 1 172 ? 22.276  1.301   -13.168 1.00 37.80  ? 172 SER I C   1 
ATOM   2807 O O   . SER B 1 172 ? 22.523  0.316   -13.872 1.00 43.32  ? 172 SER I O   1 
ATOM   2808 C CB  . SER B 1 172 ? 19.784  1.420   -12.998 1.00 44.92  ? 172 SER I CB  1 
ATOM   2809 O OG  . SER B 1 172 ? 19.714  2.694   -13.616 1.00 54.10  ? 172 SER I OG  1 
ATOM   2810 N N   . SER B 1 173 ? 23.007  2.415   -13.213 1.00 34.75  ? 173 SER I N   1 
ATOM   2811 C CA  . SER B 1 173 ? 24.218  2.517   -14.016 1.00 31.49  ? 173 SER I CA  1 
ATOM   2812 C C   . SER B 1 173 ? 25.408  1.796   -13.398 1.00 34.94  ? 173 SER I C   1 
ATOM   2813 O O   . SER B 1 173 ? 26.460  1.712   -14.042 1.00 37.39  ? 173 SER I O   1 
ATOM   2814 C CB  . SER B 1 173 ? 24.580  3.989   -14.234 1.00 32.88  ? 173 SER I CB  1 
ATOM   2815 O OG  . SER B 1 173 ? 24.845  4.636   -13.000 1.00 39.15  ? 173 SER I OG  1 
ATOM   2816 N N   . GLY B 1 174 ? 25.273  1.272   -12.181 1.00 37.47  ? 174 GLY I N   1 
ATOM   2817 C CA  . GLY B 1 174 ? 26.394  0.694   -11.473 1.00 31.20  ? 174 GLY I CA  1 
ATOM   2818 C C   . GLY B 1 174 ? 27.271  1.688   -10.746 1.00 35.24  ? 174 GLY I C   1 
ATOM   2819 O O   . GLY B 1 174 ? 28.257  1.277   -10.120 1.00 35.89  ? 174 GLY I O   1 
ATOM   2820 N N   . LEU B 1 175 ? 26.952  2.977   -10.807 1.00 34.13  ? 175 LEU I N   1 
ATOM   2821 C CA  . LEU B 1 175 ? 27.713  4.015   -10.131 1.00 31.36  ? 175 LEU I CA  1 
ATOM   2822 C C   . LEU B 1 175 ? 26.978  4.462   -8.872  1.00 34.63  ? 175 LEU I C   1 
ATOM   2823 O O   . LEU B 1 175 ? 25.746  4.430   -8.806  1.00 32.48  ? 175 LEU I O   1 
ATOM   2824 C CB  . LEU B 1 175 ? 27.936  5.211   -11.058 1.00 37.36  ? 175 LEU I CB  1 
ATOM   2825 C CG  . LEU B 1 175 ? 28.555  4.896   -12.421 1.00 36.70  ? 175 LEU I CG  1 
ATOM   2826 C CD1 . LEU B 1 175 ? 28.667  6.159   -13.261 1.00 27.84  ? 175 LEU I CD1 1 
ATOM   2827 C CD2 . LEU B 1 175 ? 29.909  4.222   -12.267 1.00 32.74  ? 175 LEU I CD2 1 
ATOM   2828 N N   . TYR B 1 176 ? 27.745  4.883   -7.871  1.00 31.30  ? 176 TYR I N   1 
ATOM   2829 C CA  . TYR B 1 176 ? 27.175  5.278   -6.592  1.00 34.01  ? 176 TYR I CA  1 
ATOM   2830 C C   . TYR B 1 176 ? 26.812  6.761   -6.577  1.00 33.10  ? 176 TYR I C   1 
ATOM   2831 O O   . TYR B 1 176 ? 27.375  7.577   -7.311  1.00 33.83  ? 176 TYR I O   1 
ATOM   2832 C CB  . TYR B 1 176 ? 28.142  4.972   -5.448  1.00 32.11  ? 176 TYR I CB  1 
ATOM   2833 C CG  . TYR B 1 176 ? 28.374  3.498   -5.208  1.00 37.35  ? 176 TYR I CG  1 
ATOM   2834 C CD1 . TYR B 1 176 ? 27.499  2.755   -4.428  1.00 33.99  ? 176 TYR I CD1 1 
ATOM   2835 C CD2 . TYR B 1 176 ? 29.476  2.852   -5.751  1.00 32.49  ? 176 TYR I CD2 1 
ATOM   2836 C CE1 . TYR B 1 176 ? 27.710  1.407   -4.204  1.00 29.03  ? 176 TYR I CE1 1 
ATOM   2837 C CE2 . TYR B 1 176 ? 29.696  1.505   -5.531  1.00 33.40  ? 176 TYR I CE2 1 
ATOM   2838 C CZ  . TYR B 1 176 ? 28.810  0.788   -4.756  1.00 31.37  ? 176 TYR I CZ  1 
ATOM   2839 O OH  . TYR B 1 176 ? 29.027  -0.554  -4.536  1.00 37.36  ? 176 TYR I OH  1 
ATOM   2840 N N   . SER B 1 177 ? 25.869  7.103   -5.701  1.00 36.84  ? 177 SER I N   1 
ATOM   2841 C CA  . SER B 1 177 ? 25.456  8.485   -5.511  1.00 37.20  ? 177 SER I CA  1 
ATOM   2842 C C   . SER B 1 177 ? 25.042  8.682   -4.061  1.00 35.78  ? 177 SER I C   1 
ATOM   2843 O O   . SER B 1 177 ? 24.362  7.830   -3.483  1.00 33.78  ? 177 SER I O   1 
ATOM   2844 C CB  . SER B 1 177 ? 24.302  8.859   -6.450  1.00 34.65  ? 177 SER I CB  1 
ATOM   2845 O OG  . SER B 1 177 ? 23.851  10.180  -6.206  1.00 40.44  ? 177 SER I OG  1 
ATOM   2846 N N   . LEU B 1 178 ? 25.453  9.808   -3.482  1.00 33.51  ? 178 LEU I N   1 
ATOM   2847 C CA  . LEU B 1 178 ? 25.058  10.168  -2.128  1.00 40.01  ? 178 LEU I CA  1 
ATOM   2848 C C   . LEU B 1 178 ? 24.859  11.674  -2.042  1.00 35.24  ? 178 LEU I C   1 
ATOM   2849 O O   . LEU B 1 178 ? 25.179  12.426  -2.967  1.00 34.93  ? 178 LEU I O   1 
ATOM   2850 C CB  . LEU B 1 178 ? 26.082  9.686   -1.083  1.00 34.65  ? 178 LEU I CB  1 
ATOM   2851 C CG  . LEU B 1 178 ? 27.513  10.236  -0.990  1.00 37.01  ? 178 LEU I CG  1 
ATOM   2852 C CD1 . LEU B 1 178 ? 27.592  11.585  -0.279  1.00 39.10  ? 178 LEU I CD1 1 
ATOM   2853 C CD2 . LEU B 1 178 ? 28.389  9.220   -0.281  1.00 37.57  ? 178 LEU I CD2 1 
ATOM   2854 N N   . SER B 1 179 ? 24.295  12.106  -0.919  1.00 31.84  ? 179 SER I N   1 
ATOM   2855 C CA  . SER B 1 179 ? 24.118  13.517  -0.622  1.00 39.37  ? 179 SER I CA  1 
ATOM   2856 C C   . SER B 1 179 ? 24.632  13.806  0.781   1.00 32.55  ? 179 SER I C   1 
ATOM   2857 O O   . SER B 1 179 ? 24.523  12.970  1.683   1.00 32.20  ? 179 SER I O   1 
ATOM   2858 C CB  . SER B 1 179 ? 22.645  13.935  -0.739  1.00 34.88  ? 179 SER I CB  1 
ATOM   2859 O OG  . SER B 1 179 ? 21.838  13.210  0.172   1.00 41.90  ? 179 SER I OG  1 
ATOM   2860 N N   . SER B 1 180 ? 25.195  14.999  0.955   1.00 32.31  ? 180 SER I N   1 
ATOM   2861 C CA  . SER B 1 180 ? 25.616  15.478  2.266   1.00 28.10  ? 180 SER I CA  1 
ATOM   2862 C C   . SER B 1 180 ? 24.961  16.827  2.497   1.00 35.85  ? 180 SER I C   1 
ATOM   2863 O O   . SER B 1 180 ? 25.222  17.777  1.755   1.00 35.90  ? 180 SER I O   1 
ATOM   2864 C CB  . SER B 1 180 ? 27.140  15.589  2.358   1.00 35.53  ? 180 SER I CB  1 
ATOM   2865 O OG  . SER B 1 180 ? 27.544  16.012  3.649   1.00 35.26  ? 180 SER I OG  1 
ATOM   2866 N N   . VAL B 1 181 ? 24.130  16.918  3.532   1.00 32.18  ? 181 VAL I N   1 
ATOM   2867 C CA  . VAL B 1 181 ? 23.335  18.107  3.794   1.00 30.85  ? 181 VAL I CA  1 
ATOM   2868 C C   . VAL B 1 181 ? 23.708  18.659  5.165   1.00 37.83  ? 181 VAL I C   1 
ATOM   2869 O O   . VAL B 1 181 ? 24.361  18.001  5.972   1.00 37.13  ? 181 VAL I O   1 
ATOM   2870 C CB  . VAL B 1 181 ? 21.822  17.824  3.714   1.00 32.61  ? 181 VAL I CB  1 
ATOM   2871 C CG1 . VAL B 1 181 ? 21.479  17.133  2.403   1.00 25.21  ? 181 VAL I CG1 1 
ATOM   2872 C CG2 . VAL B 1 181 ? 21.384  16.972  4.897   1.00 32.77  ? 181 VAL I CG2 1 
ATOM   2873 N N   . VAL B 1 182 ? 23.287  19.896  5.409   1.00 31.78  ? 182 VAL I N   1 
ATOM   2874 C CA  . VAL B 1 182 ? 23.491  20.542  6.700   1.00 32.85  ? 182 VAL I CA  1 
ATOM   2875 C C   . VAL B 1 182 ? 22.456  21.648  6.846   1.00 36.43  ? 182 VAL I C   1 
ATOM   2876 O O   . VAL B 1 182 ? 22.130  22.352  5.881   1.00 37.90  ? 182 VAL I O   1 
ATOM   2877 C CB  . VAL B 1 182 ? 24.937  21.077  6.845   1.00 31.04  ? 182 VAL I CB  1 
ATOM   2878 C CG1 . VAL B 1 182 ? 25.269  22.042  5.724   1.00 33.15  ? 182 VAL I CG1 1 
ATOM   2879 C CG2 . VAL B 1 182 ? 25.135  21.736  8.204   1.00 30.32  ? 182 VAL I CG2 1 
ATOM   2880 N N   . THR B 1 183 ? 21.934  21.784  8.062   1.00 33.39  ? 183 THR I N   1 
ATOM   2881 C CA  . THR B 1 183 ? 21.015  22.853  8.415   1.00 33.34  ? 183 THR I CA  1 
ATOM   2882 C C   . THR B 1 183 ? 21.765  23.929  9.188   1.00 38.24  ? 183 THR I C   1 
ATOM   2883 O O   . THR B 1 183 ? 22.577  23.630  10.069  1.00 38.86  ? 183 THR I O   1 
ATOM   2884 C CB  . THR B 1 183 ? 19.846  22.326  9.251   1.00 37.01  ? 183 THR I CB  1 
ATOM   2885 O OG1 . THR B 1 183 ? 20.348  21.594  10.376  1.00 39.46  ? 183 THR I OG1 1 
ATOM   2886 C CG2 . THR B 1 183 ? 18.958  21.417  8.414   1.00 40.73  ? 183 THR I CG2 1 
ATOM   2887 N N   . VAL B 1 184 ? 21.481  25.182  8.851   1.00 38.99  ? 184 VAL I N   1 
ATOM   2888 C CA  . VAL B 1 184 ? 22.173  26.343  9.403   1.00 38.53  ? 184 VAL I CA  1 
ATOM   2889 C C   . VAL B 1 184 ? 21.130  27.422  9.668   1.00 42.87  ? 184 VAL I C   1 
ATOM   2890 O O   . VAL B 1 184 ? 19.979  27.283  9.227   1.00 38.89  ? 184 VAL I O   1 
ATOM   2891 C CB  . VAL B 1 184 ? 23.270  26.848  8.449   1.00 43.02  ? 184 VAL I CB  1 
ATOM   2892 C CG1 . VAL B 1 184 ? 24.380  25.815  8.300   1.00 35.59  ? 184 VAL I CG1 1 
ATOM   2893 C CG2 . VAL B 1 184 ? 22.675  27.201  7.092   1.00 35.03  ? 184 VAL I CG2 1 
ATOM   2894 N N   . PRO B 1 185 ? 21.454  28.482  10.408  1.00 46.64  ? 185 PRO I N   1 
ATOM   2895 C CA  . PRO B 1 185 ? 20.528  29.616  10.484  1.00 43.61  ? 185 PRO I CA  1 
ATOM   2896 C C   . PRO B 1 185 ? 20.392  30.292  9.129   1.00 42.52  ? 185 PRO I C   1 
ATOM   2897 O O   . PRO B 1 185 ? 21.369  30.448  8.392   1.00 41.47  ? 185 PRO I O   1 
ATOM   2898 C CB  . PRO B 1 185 ? 21.182  30.546  11.512  1.00 43.77  ? 185 PRO I CB  1 
ATOM   2899 C CG  . PRO B 1 185 ? 22.055  29.652  12.327  1.00 35.39  ? 185 PRO I CG  1 
ATOM   2900 C CD  . PRO B 1 185 ? 22.561  28.612  11.372  1.00 36.67  ? 185 PRO I CD  1 
ATOM   2901 N N   . SER B 1 186 ? 19.160  30.686  8.802   1.00 45.16  ? 186 SER I N   1 
ATOM   2902 C CA  . SER B 1 186 ? 18.911  31.356  7.530   1.00 41.13  ? 186 SER I CA  1 
ATOM   2903 C C   . SER B 1 186 ? 19.630  32.698  7.465   1.00 42.59  ? 186 SER I C   1 
ATOM   2904 O O   . SER B 1 186 ? 20.101  33.109  6.398   1.00 45.10  ? 186 SER I O   1 
ATOM   2905 C CB  . SER B 1 186 ? 17.408  31.529  7.313   1.00 45.89  ? 186 SER I CB  1 
ATOM   2906 O OG  . SER B 1 186 ? 16.782  32.054  8.470   1.00 55.66  ? 186 SER I OG  1 
ATOM   2907 N N   . SER B 1 187 ? 19.715  33.401  8.597   1.00 44.80  ? 187 SER I N   1 
ATOM   2908 C CA  . SER B 1 187 ? 20.375  34.701  8.642   1.00 47.75  ? 187 SER I CA  1 
ATOM   2909 C C   . SER B 1 187 ? 21.866  34.627  8.336   1.00 50.13  ? 187 SER I C   1 
ATOM   2910 O O   . SER B 1 187 ? 22.478  35.670  8.079   1.00 59.34  ? 187 SER I O   1 
ATOM   2911 C CB  . SER B 1 187 ? 20.160  35.342  10.016  1.00 51.93  ? 187 SER I CB  1 
ATOM   2912 O OG  . SER B 1 187 ? 20.754  34.565  11.041  1.00 47.20  ? 187 SER I OG  1 
ATOM   2913 N N   . SER B 1 188 ? 22.463  33.438  8.359   1.00 45.38  ? 188 SER I N   1 
ATOM   2914 C CA  . SER B 1 188 ? 23.882  33.265  8.075   1.00 42.22  ? 188 SER I CA  1 
ATOM   2915 C C   . SER B 1 188 ? 24.173  33.038  6.597   1.00 46.54  ? 188 SER I C   1 
ATOM   2916 O O   . SER B 1 188 ? 25.345  32.919  6.224   1.00 44.16  ? 188 SER I O   1 
ATOM   2917 C CB  . SER B 1 188 ? 24.444  32.096  8.891   1.00 45.48  ? 188 SER I CB  1 
ATOM   2918 O OG  . SER B 1 188 ? 24.158  30.857  8.266   1.00 40.37  ? 188 SER I OG  1 
ATOM   2919 N N   . LEU B 1 189 ? 23.143  32.980  5.750   1.00 48.26  ? 189 LEU I N   1 
ATOM   2920 C CA  . LEU B 1 189 ? 23.341  32.649  4.343   1.00 46.38  ? 189 LEU I CA  1 
ATOM   2921 C C   . LEU B 1 189 ? 24.065  33.739  3.564   1.00 43.64  ? 189 LEU I C   1 
ATOM   2922 O O   . LEU B 1 189 ? 24.653  33.444  2.518   1.00 49.67  ? 189 LEU I O   1 
ATOM   2923 C CB  . LEU B 1 189 ? 21.992  32.359  3.684   1.00 43.78  ? 189 LEU I CB  1 
ATOM   2924 C CG  . LEU B 1 189 ? 21.269  31.091  4.140   1.00 40.70  ? 189 LEU I CG  1 
ATOM   2925 C CD1 . LEU B 1 189 ? 20.140  30.749  3.181   1.00 45.60  ? 189 LEU I CD1 1 
ATOM   2926 C CD2 . LEU B 1 189 ? 22.249  29.935  4.243   1.00 42.26  ? 189 LEU I CD2 1 
ATOM   2927 N N   . GLY B 1 190 ? 24.042  34.981  4.038   1.00 45.28  ? 190 GLY I N   1 
ATOM   2928 C CA  . GLY B 1 190 ? 24.694  36.061  3.322   1.00 47.05  ? 190 GLY I CA  1 
ATOM   2929 C C   . GLY B 1 190 ? 26.067  36.408  3.857   1.00 49.49  ? 190 GLY I C   1 
ATOM   2930 O O   . GLY B 1 190 ? 26.824  37.145  3.217   1.00 47.70  ? 190 GLY I O   1 
ATOM   2931 N N   . THR B 1 191 ? 26.402  35.877  5.034   1.00 51.31  ? 191 THR I N   1 
ATOM   2932 C CA  . THR B 1 191 ? 27.648  36.204  5.709   1.00 52.91  ? 191 THR I CA  1 
ATOM   2933 C C   . THR B 1 191 ? 28.600  35.027  5.866   1.00 51.12  ? 191 THR I C   1 
ATOM   2934 O O   . THR B 1 191 ? 29.810  35.252  5.977   1.00 49.62  ? 191 THR I O   1 
ATOM   2935 C CB  . THR B 1 191 ? 27.370  36.795  7.101   1.00 47.22  ? 191 THR I CB  1 
ATOM   2936 O OG1 . THR B 1 191 ? 26.891  35.765  7.974   1.00 49.74  ? 191 THR I OG1 1 
ATOM   2937 C CG2 . THR B 1 191 ? 26.330  37.903  7.013   1.00 44.97  ? 191 THR I CG2 1 
ATOM   2938 N N   . GLN B 1 192 ? 28.103  33.794  5.877   1.00 52.40  ? 192 GLN I N   1 
ATOM   2939 C CA  . GLN B 1 192 ? 28.920  32.612  6.120   1.00 47.63  ? 192 GLN I CA  1 
ATOM   2940 C C   . GLN B 1 192 ? 29.107  31.838  4.823   1.00 43.68  ? 192 GLN I C   1 
ATOM   2941 O O   . GLN B 1 192 ? 28.133  31.552  4.118   1.00 41.93  ? 192 GLN I O   1 
ATOM   2942 C CB  . GLN B 1 192 ? 28.277  31.714  7.180   1.00 47.48  ? 192 GLN I CB  1 
ATOM   2943 C CG  . GLN B 1 192 ? 28.997  30.393  7.400   1.00 42.25  ? 192 GLN I CG  1 
ATOM   2944 C CD  . GLN B 1 192 ? 30.359  30.567  8.040   1.00 45.51  ? 192 GLN I CD  1 
ATOM   2945 O OE1 . GLN B 1 192 ? 30.521  31.344  8.981   1.00 50.54  ? 192 GLN I OE1 1 
ATOM   2946 N NE2 . GLN B 1 192 ? 31.350  29.844  7.530   1.00 42.81  ? 192 GLN I NE2 1 
ATOM   2947 N N   . THR B 1 193 ? 30.358  31.503  4.513   1.00 46.87  ? 193 THR I N   1 
ATOM   2948 C CA  . THR B 1 193 ? 30.658  30.685  3.349   1.00 44.27  ? 193 THR I CA  1 
ATOM   2949 C C   . THR B 1 193 ? 30.516  29.208  3.693   1.00 41.38  ? 193 THR I C   1 
ATOM   2950 O O   . THR B 1 193 ? 30.906  28.769  4.779   1.00 46.52  ? 193 THR I O   1 
ATOM   2951 C CB  . THR B 1 193 ? 32.075  30.972  2.848   1.00 46.36  ? 193 THR I CB  1 
ATOM   2952 O OG1 . THR B 1 193 ? 32.224  32.377  2.609   1.00 55.58  ? 193 THR I OG1 1 
ATOM   2953 C CG2 . THR B 1 193 ? 32.359  30.213  1.558   1.00 45.88  ? 193 THR I CG2 1 
ATOM   2954 N N   . TYR B 1 194 ? 29.952  28.442  2.762   1.00 40.05  ? 194 TYR I N   1 
ATOM   2955 C CA  . TYR B 1 194 ? 29.741  27.012  2.949   1.00 38.11  ? 194 TYR I CA  1 
ATOM   2956 C C   . TYR B 1 194 ? 30.385  26.267  1.792   1.00 46.58  ? 194 TYR I C   1 
ATOM   2957 O O   . TYR B 1 194 ? 29.986  26.442  0.636   1.00 36.35  ? 194 TYR I O   1 
ATOM   2958 C CB  . TYR B 1 194 ? 28.250  26.681  3.056   1.00 37.07  ? 194 TYR I CB  1 
ATOM   2959 C CG  . TYR B 1 194 ? 27.608  27.242  4.305   1.00 39.02  ? 194 TYR I CG  1 
ATOM   2960 C CD1 . TYR B 1 194 ? 27.820  26.647  5.542   1.00 35.42  ? 194 TYR I CD1 1 
ATOM   2961 C CD2 . TYR B 1 194 ? 26.796  28.368  4.252   1.00 38.24  ? 194 TYR I CD2 1 
ATOM   2962 C CE1 . TYR B 1 194 ? 27.241  27.155  6.690   1.00 36.23  ? 194 TYR I CE1 1 
ATOM   2963 C CE2 . TYR B 1 194 ? 26.210  28.883  5.396   1.00 40.51  ? 194 TYR I CE2 1 
ATOM   2964 C CZ  . TYR B 1 194 ? 26.436  28.271  6.611   1.00 39.39  ? 194 TYR I CZ  1 
ATOM   2965 O OH  . TYR B 1 194 ? 25.859  28.778  7.752   1.00 38.91  ? 194 TYR I OH  1 
ATOM   2966 N N   . ILE B 1 195 ? 31.376  25.436  2.107   1.00 44.64  ? 195 ILE I N   1 
ATOM   2967 C CA  . ILE B 1 195 ? 32.118  24.663  1.119   1.00 37.52  ? 195 ILE I CA  1 
ATOM   2968 C C   . ILE B 1 195 ? 32.143  23.213  1.574   1.00 40.06  ? 195 ILE I C   1 
ATOM   2969 O O   . ILE B 1 195 ? 32.505  22.924  2.720   1.00 38.87  ? 195 ILE I O   1 
ATOM   2970 C CB  . ILE B 1 195 ? 33.554  25.190  0.936   1.00 44.08  ? 195 ILE I CB  1 
ATOM   2971 C CG1 . ILE B 1 195 ? 33.543  26.661  0.514   1.00 48.00  ? 195 ILE I CG1 1 
ATOM   2972 C CG2 . ILE B 1 195 ? 34.310  24.342  -0.077  1.00 41.85  ? 195 ILE I CG2 1 
ATOM   2973 C CD1 . ILE B 1 195 ? 34.912  27.302  0.504   1.00 48.56  ? 195 ILE I CD1 1 
ATOM   2974 N N   . CYS B 1 196 ? 31.760  22.305  0.682   1.00 43.37  ? 196 CYS I N   1 
ATOM   2975 C CA  . CYS B 1 196 ? 31.849  20.877  0.946   1.00 43.48  ? 196 CYS I CA  1 
ATOM   2976 C C   . CYS B 1 196 ? 33.124  20.331  0.319   1.00 38.39  ? 196 CYS I C   1 
ATOM   2977 O O   . CYS B 1 196 ? 33.431  20.624  -0.843  1.00 43.33  ? 196 CYS I O   1 
ATOM   2978 C CB  . CYS B 1 196 ? 30.617  20.138  0.416   1.00 41.90  ? 196 CYS I CB  1 
ATOM   2979 S SG  . CYS B 1 196 ? 30.461  20.057  -1.384  1.00 51.60  ? 196 CYS I SG  1 
ATOM   2980 N N   . ASN B 1 197 ? 33.867  19.553  1.100   1.00 39.81  ? 197 ASN I N   1 
ATOM   2981 C CA  . ASN B 1 197 ? 35.137  18.970  0.688   1.00 40.81  ? 197 ASN I CA  1 
ATOM   2982 C C   . ASN B 1 197 ? 34.908  17.477  0.493   1.00 36.20  ? 197 ASN I C   1 
ATOM   2983 O O   . ASN B 1 197 ? 34.709  16.743  1.467   1.00 39.23  ? 197 ASN I O   1 
ATOM   2984 C CB  . ASN B 1 197 ? 36.223  19.232  1.730   1.00 38.67  ? 197 ASN I CB  1 
ATOM   2985 C CG  . ASN B 1 197 ? 36.158  20.636  2.301   1.00 42.87  ? 197 ASN I CG  1 
ATOM   2986 O OD1 . ASN B 1 197 ? 35.857  20.822  3.479   1.00 37.87  ? 197 ASN I OD1 1 
ATOM   2987 N ND2 . ASN B 1 197 ? 36.441  21.631  1.468   1.00 40.98  ? 197 ASN I ND2 1 
ATOM   2988 N N   . VAL B 1 198 ? 34.914  17.042  -0.764  1.00 38.20  ? 198 VAL I N   1 
ATOM   2989 C CA  . VAL B 1 198 ? 34.663  15.659  -1.143  1.00 38.00  ? 198 VAL I CA  1 
ATOM   2990 C C   . VAL B 1 198 ? 35.988  15.037  -1.555  1.00 37.80  ? 198 VAL I C   1 
ATOM   2991 O O   . VAL B 1 198 ? 36.746  15.634  -2.328  1.00 42.38  ? 198 VAL I O   1 
ATOM   2992 C CB  . VAL B 1 198 ? 33.635  15.570  -2.284  1.00 32.79  ? 198 VAL I CB  1 
ATOM   2993 C CG1 . VAL B 1 198 ? 33.437  14.126  -2.717  1.00 29.25  ? 198 VAL I CG1 1 
ATOM   2994 C CG2 . VAL B 1 198 ? 32.317  16.198  -1.860  1.00 35.88  ? 198 VAL I CG2 1 
ATOM   2995 N N   . ASN B 1 199 ? 36.265  13.841  -1.042  1.00 36.90  ? 199 ASN I N   1 
ATOM   2996 C CA  . ASN B 1 199 ? 37.493  13.119  -1.347  1.00 40.10  ? 199 ASN I CA  1 
ATOM   2997 C C   . ASN B 1 199 ? 37.141  11.708  -1.792  1.00 40.13  ? 199 ASN I C   1 
ATOM   2998 O O   . ASN B 1 199 ? 36.408  10.999  -1.095  1.00 38.73  ? 199 ASN I O   1 
ATOM   2999 C CB  . ASN B 1 199 ? 38.427  13.080  -0.131  1.00 44.53  ? 199 ASN I CB  1 
ATOM   3000 C CG  . ASN B 1 199 ? 39.863  12.769  -0.506  1.00 58.18  ? 199 ASN I CG  1 
ATOM   3001 O OD1 . ASN B 1 199 ? 40.129  12.133  -1.525  1.00 58.67  ? 199 ASN I OD1 1 
ATOM   3002 N ND2 . ASN B 1 199 ? 40.799  13.220  0.321   1.00 58.67  ? 199 ASN I ND2 1 
ATOM   3003 N N   . HIS B 1 200 ? 37.662  11.309  -2.952  1.00 43.13  ? 200 HIS I N   1 
ATOM   3004 C CA  . HIS B 1 200 ? 37.499  9.963   -3.498  1.00 42.63  ? 200 HIS I CA  1 
ATOM   3005 C C   . HIS B 1 200 ? 38.890  9.457   -3.872  1.00 44.49  ? 200 HIS I C   1 
ATOM   3006 O O   . HIS B 1 200 ? 39.417  9.798   -4.935  1.00 43.66  ? 200 HIS I O   1 
ATOM   3007 C CB  . HIS B 1 200 ? 36.562  9.967   -4.702  1.00 42.09  ? 200 HIS I CB  1 
ATOM   3008 C CG  . HIS B 1 200 ? 36.264  8.603   -5.240  1.00 40.47  ? 200 HIS I CG  1 
ATOM   3009 N ND1 . HIS B 1 200 ? 36.673  8.190   -6.490  1.00 43.54  ? 200 HIS I ND1 1 
ATOM   3010 C CD2 . HIS B 1 200 ? 35.597  7.557   -4.699  1.00 41.02  ? 200 HIS I CD2 1 
ATOM   3011 C CE1 . HIS B 1 200 ? 36.272  6.948   -6.694  1.00 37.97  ? 200 HIS I CE1 1 
ATOM   3012 N NE2 . HIS B 1 200 ? 35.616  6.541   -5.623  1.00 36.66  ? 200 HIS I NE2 1 
ATOM   3013 N N   . LYS B 1 201 ? 39.481  8.654   -2.994  1.00 44.13  ? 201 LYS I N   1 
ATOM   3014 C CA  . LYS B 1 201 ? 40.846  8.160   -3.140  1.00 46.74  ? 201 LYS I CA  1 
ATOM   3015 C C   . LYS B 1 201 ? 41.051  7.196   -4.308  1.00 44.77  ? 201 LYS I C   1 
ATOM   3016 O O   . LYS B 1 201 ? 42.065  7.319   -5.010  1.00 46.16  ? 201 LYS I O   1 
ATOM   3017 C CB  . LYS B 1 201 ? 41.303  7.539   -1.818  1.00 46.36  ? 201 LYS I CB  1 
ATOM   3018 C CG  . LYS B 1 201 ? 41.701  8.631   -0.873  1.00 50.57  ? 201 LYS I CG  1 
ATOM   3019 C CD  . LYS B 1 201 ? 42.285  8.189   0.438   1.00 57.79  ? 201 LYS I CD  1 
ATOM   3020 C CE  . LYS B 1 201 ? 42.294  9.430   1.286   1.00 58.74  ? 201 LYS I CE  1 
ATOM   3021 N NZ  . LYS B 1 201 ? 43.020  10.468  0.485   1.00 67.96  ? 201 LYS I NZ  1 
ATOM   3022 N N   . PRO B 1 202 ? 40.164  6.218   -4.548  1.00 39.37  ? 202 PRO I N   1 
ATOM   3023 C CA  . PRO B 1 202 ? 40.409  5.293   -5.669  1.00 39.94  ? 202 PRO I CA  1 
ATOM   3024 C C   . PRO B 1 202 ? 40.660  5.985   -7.001  1.00 45.53  ? 202 PRO I C   1 
ATOM   3025 O O   . PRO B 1 202 ? 41.389  5.441   -7.841  1.00 43.12  ? 202 PRO I O   1 
ATOM   3026 C CB  . PRO B 1 202 ? 39.131  4.450   -5.702  1.00 38.61  ? 202 PRO I CB  1 
ATOM   3027 C CG  . PRO B 1 202 ? 38.681  4.432   -4.294  1.00 34.94  ? 202 PRO I CG  1 
ATOM   3028 C CD  . PRO B 1 202 ? 38.976  5.810   -3.772  1.00 36.22  ? 202 PRO I CD  1 
ATOM   3029 N N   . SER B 1 203 ? 40.092  7.171   -7.218  1.00 44.24  ? 203 SER I N   1 
ATOM   3030 C CA  . SER B 1 203 ? 40.354  7.959   -8.415  1.00 45.96  ? 203 SER I CA  1 
ATOM   3031 C C   . SER B 1 203 ? 41.266  9.151   -8.160  1.00 47.30  ? 203 SER I C   1 
ATOM   3032 O O   . SER B 1 203 ? 41.566  9.894   -9.102  1.00 43.46  ? 203 SER I O   1 
ATOM   3033 C CB  . SER B 1 203 ? 39.035  8.444   -9.029  1.00 42.37  ? 203 SER I CB  1 
ATOM   3034 O OG  . SER B 1 203 ? 38.370  9.344   -8.159  1.00 45.43  ? 203 SER I OG  1 
ATOM   3035 N N   . ASN B 1 204 ? 41.720  9.347   -6.920  1.00 43.28  ? 204 ASN I N   1 
ATOM   3036 C CA  . ASN B 1 204 ? 42.502  10.521  -6.527  1.00 46.70  ? 204 ASN I CA  1 
ATOM   3037 C C   . ASN B 1 204 ? 41.796  11.807  -6.951  1.00 47.11  ? 204 ASN I C   1 
ATOM   3038 O O   . ASN B 1 204 ? 42.365  12.679  -7.611  1.00 51.28  ? 204 ASN I O   1 
ATOM   3039 C CB  . ASN B 1 204 ? 43.924  10.462  -7.086  1.00 49.22  ? 204 ASN I CB  1 
ATOM   3040 C CG  . ASN B 1 204 ? 44.832  11.518  -6.478  1.00 55.85  ? 204 ASN I CG  1 
ATOM   3041 O OD1 . ASN B 1 204 ? 45.085  12.562  -7.082  1.00 51.40  ? 204 ASN I OD1 1 
ATOM   3042 N ND2 . ASN B 1 204 ? 45.329  11.249  -5.277  1.00 55.74  ? 204 ASN I ND2 1 
ATOM   3043 N N   . THR B 1 205 ? 40.529  11.910  -6.571  1.00 44.81  ? 205 THR I N   1 
ATOM   3044 C CA  . THR B 1 205 ? 39.718  13.083  -6.847  1.00 44.54  ? 205 THR I CA  1 
ATOM   3045 C C   . THR B 1 205 ? 39.454  13.820  -5.544  1.00 47.20  ? 205 THR I C   1 
ATOM   3046 O O   . THR B 1 205 ? 39.123  13.199  -4.530  1.00 46.89  ? 205 THR I O   1 
ATOM   3047 C CB  . THR B 1 205 ? 38.391  12.692  -7.501  1.00 47.05  ? 205 THR I CB  1 
ATOM   3048 O OG1 . THR B 1 205 ? 38.642  11.864  -8.644  1.00 50.14  ? 205 THR I OG1 1 
ATOM   3049 C CG2 . THR B 1 205 ? 37.620  13.931  -7.936  1.00 50.55  ? 205 THR I CG2 1 
ATOM   3050 N N   . LYS B 1 206 ? 39.617  15.137  -5.566  1.00 45.87  ? 206 LYS I N   1 
ATOM   3051 C CA  . LYS B 1 206 ? 39.248  15.960  -4.426  1.00 45.13  ? 206 LYS I CA  1 
ATOM   3052 C C   . LYS B 1 206 ? 38.583  17.220  -4.944  1.00 49.43  ? 206 LYS I C   1 
ATOM   3053 O O   . LYS B 1 206 ? 39.162  17.933  -5.769  1.00 52.43  ? 206 LYS I O   1 
ATOM   3054 C CB  . LYS B 1 206 ? 40.438  16.358  -3.565  1.00 48.76  ? 206 LYS I CB  1 
ATOM   3055 C CG  . LYS B 1 206 ? 39.981  16.891  -2.231  1.00 49.31  ? 206 LYS I CG  1 
ATOM   3056 C CD  . LYS B 1 206 ? 41.101  17.568  -1.504  1.00 57.29  ? 206 LYS I CD  1 
ATOM   3057 C CE  . LYS B 1 206 ? 40.865  19.070  -1.621  1.00 57.67  ? 206 LYS I CE  1 
ATOM   3058 N NZ  . LYS B 1 206 ? 42.080  19.910  -1.458  1.00 58.79  ? 206 LYS I NZ  1 
ATOM   3059 N N   . VAL B 1 207 ? 37.382  17.498  -4.457  1.00 49.98  ? 207 VAL I N   1 
ATOM   3060 C CA  . VAL B 1 207 ? 36.597  18.637  -4.914  1.00 44.79  ? 207 VAL I CA  1 
ATOM   3061 C C   . VAL B 1 207 ? 36.246  19.495  -3.707  1.00 49.55  ? 207 VAL I C   1 
ATOM   3062 O O   . VAL B 1 207 ? 35.845  18.973  -2.662  1.00 45.26  ? 207 VAL I O   1 
ATOM   3063 C CB  . VAL B 1 207 ? 35.327  18.186  -5.658  1.00 48.78  ? 207 VAL I CB  1 
ATOM   3064 C CG1 . VAL B 1 207 ? 34.505  19.390  -6.085  1.00 47.64  ? 207 VAL I CG1 1 
ATOM   3065 C CG2 . VAL B 1 207 ? 35.697  17.332  -6.863  1.00 44.85  ? 207 VAL I CG2 1 
ATOM   3066 N N   . ASP B 1 208 ? 36.405  20.807  -3.848  1.00 47.06  ? 208 ASP I N   1 
ATOM   3067 C CA  . ASP B 1 208 ? 35.967  21.772  -2.842  1.00 48.21  ? 208 ASP I CA  1 
ATOM   3068 C C   . ASP B 1 208 ? 34.877  22.616  -3.491  1.00 51.28  ? 208 ASP I C   1 
ATOM   3069 O O   . ASP B 1 208 ? 35.171  23.596  -4.183  1.00 55.27  ? 208 ASP I O   1 
ATOM   3070 C CB  . ASP B 1 208 ? 37.126  22.632  -2.349  1.00 50.85  ? 208 ASP I CB  1 
ATOM   3071 C CG  . ASP B 1 208 ? 38.085  21.862  -1.463  1.00 54.57  ? 208 ASP I CG  1 
ATOM   3072 O OD1 . ASP B 1 208 ? 37.609  21.131  -0.569  1.00 52.68  ? 208 ASP I OD1 1 
ATOM   3073 O OD2 . ASP B 1 208 ? 39.311  21.999  -1.649  1.00 60.85  ? 208 ASP I OD2 1 
ATOM   3074 N N   . LYS B 1 209 ? 33.622  22.234  -3.270  1.00 48.44  ? 209 LYS I N   1 
ATOM   3075 C CA  . LYS B 1 209 ? 32.497  22.855  -3.955  1.00 44.53  ? 209 LYS I CA  1 
ATOM   3076 C C   . LYS B 1 209 ? 31.850  23.888  -3.040  1.00 45.76  ? 209 LYS I C   1 
ATOM   3077 O O   . LYS B 1 209 ? 31.468  23.574  -1.906  1.00 45.54  ? 209 LYS I O   1 
ATOM   3078 C CB  . LYS B 1 209 ? 31.482  21.804  -4.405  1.00 44.27  ? 209 LYS I CB  1 
ATOM   3079 C CG  . LYS B 1 209 ? 30.371  22.379  -5.263  1.00 44.01  ? 209 LYS I CG  1 
ATOM   3080 C CD  . LYS B 1 209 ? 30.967  22.848  -6.577  1.00 44.40  ? 209 LYS I CD  1 
ATOM   3081 C CE  . LYS B 1 209 ? 29.944  22.950  -7.686  1.00 52.25  ? 209 LYS I CE  1 
ATOM   3082 N NZ  . LYS B 1 209 ? 30.545  23.532  -8.920  1.00 57.35  ? 209 LYS I NZ  1 
ATOM   3083 N N   . ARG B 1 210 ? 31.745  25.120  -3.529  1.00 41.79  ? 210 ARG I N   1 
ATOM   3084 C CA  . ARG B 1 210 ? 31.131  26.202  -2.777  1.00 46.11  ? 210 ARG I CA  1 
ATOM   3085 C C   . ARG B 1 210 ? 29.636  26.212  -3.064  1.00 43.12  ? 210 ARG I C   1 
ATOM   3086 O O   . ARG B 1 210 ? 29.222  26.163  -4.226  1.00 46.34  ? 210 ARG I O   1 
ATOM   3087 C CB  . ARG B 1 210 ? 31.768  27.540  -3.153  1.00 46.63  ? 210 ARG I CB  1 
ATOM   3088 C CG  . ARG B 1 210 ? 31.356  28.704  -2.280  1.00 51.78  ? 210 ARG I CG  1 
ATOM   3089 C CD  . ARG B 1 210 ? 32.224  29.914  -2.574  1.00 56.27  ? 210 ARG I CD  1 
ATOM   3090 N NE  . ARG B 1 210 ? 31.684  31.138  -1.996  1.00 59.38  ? 210 ARG I NE  1 
ATOM   3091 C CZ  . ARG B 1 210 ? 32.422  32.175  -1.625  1.00 64.76  ? 210 ARG I CZ  1 
ATOM   3092 N NH1 . ARG B 1 210 ? 33.739  32.167  -1.752  1.00 65.85  ? 210 ARG I NH1 1 
ATOM   3093 N NH2 . ARG B 1 210 ? 31.825  33.243  -1.105  1.00 66.74  ? 210 ARG I NH2 1 
ATOM   3094 N N   . VAL B 1 211 ? 28.832  26.271  -2.006  1.00 38.12  ? 211 VAL I N   1 
ATOM   3095 C CA  . VAL B 1 211 ? 27.377  26.224  -2.107  1.00 42.75  ? 211 VAL I CA  1 
ATOM   3096 C C   . VAL B 1 211 ? 26.855  27.626  -1.829  1.00 41.83  ? 211 VAL I C   1 
ATOM   3097 O O   . VAL B 1 211 ? 26.951  28.123  -0.700  1.00 46.74  ? 211 VAL I O   1 
ATOM   3098 C CB  . VAL B 1 211 ? 26.768  25.200  -1.140  1.00 44.36  ? 211 VAL I CB  1 
ATOM   3099 C CG1 . VAL B 1 211 ? 25.252  25.196  -1.259  1.00 44.41  ? 211 VAL I CG1 1 
ATOM   3100 C CG2 . VAL B 1 211 ? 27.336  23.815  -1.410  1.00 38.27  ? 211 VAL I CG2 1 
ATOM   3101 N N   . GLU B 1 212 ? 26.300  28.264  -2.858  1.00 42.59  ? 212 GLU I N   1 
ATOM   3102 C CA  . GLU B 1 212 ? 25.813  29.627  -2.755  1.00 50.31  ? 212 GLU I CA  1 
ATOM   3103 C C   . GLU B 1 212 ? 24.292  29.681  -2.848  1.00 46.73  ? 212 GLU I C   1 
ATOM   3104 O O   . GLU B 1 212 ? 23.692  28.941  -3.635  1.00 45.79  ? 212 GLU I O   1 
ATOM   3105 C CB  . GLU B 1 212 ? 26.422  30.491  -3.865  1.00 52.27  ? 212 GLU I CB  1 
ATOM   3106 C CG  . GLU B 1 212 ? 27.934  30.617  -3.771  1.00 50.71  ? 212 GLU I CG  1 
ATOM   3107 C CD  . GLU B 1 212 ? 28.544  31.282  -4.989  1.00 66.02  ? 212 GLU I CD  1 
ATOM   3108 O OE1 . GLU B 1 212 ? 27.913  32.206  -5.542  1.00 70.88  ? 212 GLU I OE1 1 
ATOM   3109 O OE2 . GLU B 1 212 ? 29.652  30.875  -5.394  1.00 68.20  ? 212 GLU I OE2 1 
ATOM   3110 N N   . PRO B 1 213 ? 23.649  30.542  -2.062  1.00 46.21  ? 213 PRO I N   1 
ATOM   3111 C CA  . PRO B 1 213 ? 22.185  30.625  -2.089  1.00 52.52  ? 213 PRO I CA  1 
ATOM   3112 C C   . PRO B 1 213 ? 21.674  31.134  -3.429  1.00 53.31  ? 213 PRO I C   1 
ATOM   3113 O O   . PRO B 1 213 ? 22.413  31.695  -4.241  1.00 56.22  ? 213 PRO I O   1 
ATOM   3114 C CB  . PRO B 1 213 ? 21.859  31.615  -0.963  1.00 47.64  ? 213 PRO I CB  1 
ATOM   3115 C CG  . PRO B 1 213 ? 23.086  31.647  -0.103  1.00 48.96  ? 213 PRO I CG  1 
ATOM   3116 C CD  . PRO B 1 213 ? 24.233  31.422  -1.037  1.00 46.10  ? 213 PRO I CD  1 
ATOM   3117 N N   . LYS B 1 214 ? 20.380  30.927  -3.652  1.00 58.03  ? 214 LYS I N   1 
ATOM   3118 C CA  . LYS B 1 214 ? 19.713  31.358  -4.870  1.00 62.34  ? 214 LYS I CA  1 
ATOM   3119 C C   . LYS B 1 214 ? 18.692  32.444  -4.559  1.00 66.21  ? 214 LYS I C   1 
ATOM   3120 O O   . LYS B 1 214 ? 18.277  32.635  -3.412  1.00 61.76  ? 214 LYS I O   1 
ATOM   3121 C CB  . LYS B 1 214 ? 19.009  30.191  -5.571  1.00 59.73  ? 214 LYS I CB  1 
ATOM   3122 C CG  . LYS B 1 214 ? 19.908  29.291  -6.400  1.00 62.07  ? 214 LYS I CG  1 
ATOM   3123 C CD  . LYS B 1 214 ? 19.154  28.789  -7.625  1.00 67.70  ? 214 LYS I CD  1 
ATOM   3124 C CE  . LYS B 1 214 ? 19.861  27.624  -8.296  1.00 70.11  ? 214 LYS I CE  1 
ATOM   3125 N NZ  . LYS B 1 214 ? 19.626  26.346  -7.572  1.00 68.38  ? 214 LYS I NZ  1 
ATOM   3126 N N   . SER B 1 215 ? 18.289  33.155  -5.610  1.00 64.66  ? 215 SER I N   1 
ATOM   3127 C CA  . SER B 1 215 ? 17.307  34.226  -5.497  1.00 72.51  ? 215 SER I CA  1 
ATOM   3128 C C   . SER B 1 215 ? 15.873  33.716  -5.460  1.00 75.01  ? 215 SER I C   1 
ATOM   3129 O O   . SER B 1 215 ? 14.950  34.533  -5.358  1.00 79.43  ? 215 SER I O   1 
ATOM   3130 C CB  . SER B 1 215 ? 17.471  35.210  -6.659  1.00 78.24  ? 215 SER I CB  1 
ATOM   3131 O OG  . SER B 1 215 ? 18.784  35.739  -6.696  1.00 83.56  ? 215 SER I OG  1 
ATOM   3132 N N   . CYS B 1 216 ? 15.669  32.403  -5.542  1.00 75.46  ? 216 CYS I N   1 
ATOM   3133 C CA  . CYS B 1 216 ? 14.340  31.797  -5.518  1.00 70.26  ? 216 CYS I CA  1 
ATOM   3134 C C   . CYS B 1 216 ? 13.474  32.313  -6.664  1.00 69.16  ? 216 CYS I C   1 
ATOM   3135 O O   . CYS B 1 216 ? 13.770  32.071  -7.833  1.00 70.79  ? 216 CYS I O   1 
ATOM   3136 C CB  . CYS B 1 216 ? 13.649  32.058  -4.177  1.00 64.35  ? 216 CYS I CB  1 
ATOM   3137 S SG  . CYS B 1 216 ? 14.676  31.725  -2.730  1.00 81.64  ? 216 CYS I SG  1 
ATOM   3138 N N   . UNK C 2 1   ? -55.384 -7.736  -36.437 1.00 70.45  ? 3   UNK K N   1 
ATOM   3139 C CA  . UNK C 2 1   ? -56.339 -7.129  -37.356 1.00 70.32  ? 3   UNK K CA  1 
ATOM   3140 C C   . UNK C 2 1   ? -55.842 -7.205  -38.798 1.00 65.89  ? 3   UNK K C   1 
ATOM   3141 O O   . UNK C 2 1   ? -56.632 -7.414  -39.720 1.00 72.22  ? 3   UNK K O   1 
ATOM   3142 C CB  . UNK C 2 1   ? -56.604 -5.672  -36.966 1.00 55.38  ? 3   UNK K CB  1 
ATOM   3143 N N   . VAL C 2 2   ? -54.532 -7.042  -38.972 1.00 64.17  ? 4   VAL K N   1 
ATOM   3144 C CA  . VAL C 2 2   ? -53.888 -7.003  -40.286 1.00 61.99  ? 4   VAL K CA  1 
ATOM   3145 C C   . VAL C 2 2   ? -54.280 -8.169  -41.187 1.00 59.50  ? 4   VAL K C   1 
ATOM   3146 O O   . VAL C 2 2   ? -54.419 -9.302  -40.729 1.00 61.53  ? 4   VAL K O   1 
ATOM   3147 C CB  . VAL C 2 2   ? -52.354 -6.962  -40.132 1.00 61.29  ? 4   VAL K CB  1 
ATOM   3148 C CG1 . VAL C 2 2   ? -51.693 -6.549  -41.444 1.00 57.39  ? 4   VAL K CG1 1 
ATOM   3149 C CG2 . VAL C 2 2   ? -51.961 -6.012  -39.010 1.00 63.59  ? 4   VAL K CG2 1 
ATOM   3150 N N   . GLN C 2 3   ? -54.461 -7.878  -42.475 1.00 54.40  ? 5   GLN K N   1 
ATOM   3151 C CA  . GLN C 2 3   ? -54.771 -8.905  -43.460 1.00 57.07  ? 5   GLN K CA  1 
ATOM   3152 C C   . GLN C 2 3   ? -54.068 -8.569  -44.766 1.00 59.90  ? 5   GLN K C   1 
ATOM   3153 O O   . GLN C 2 3   ? -53.985 -7.401  -45.152 1.00 61.54  ? 5   GLN K O   1 
ATOM   3154 C CB  . GLN C 2 3   ? -56.279 -9.044  -43.701 1.00 59.54  ? 5   GLN K CB  1 
ATOM   3155 C CG  . GLN C 2 3   ? -56.645 -10.308 -44.471 1.00 64.37  ? 5   GLN K CG  1 
ATOM   3156 C CD  . GLN C 2 3   ? -57.612 -10.055 -45.608 1.00 72.93  ? 5   GLN K CD  1 
ATOM   3157 O OE1 . GLN C 2 3   ? -57.976 -8.914  -45.890 1.00 75.32  ? 5   GLN K OE1 1 
ATOM   3158 N NE2 . GLN C 2 3   ? -58.031 -11.125 -46.273 1.00 67.53  ? 5   GLN K NE2 1 
ATOM   3159 N N   . LEU C 2 4   ? -53.554 -9.592  -45.438 1.00 56.51  ? 6   LEU K N   1 
ATOM   3160 C CA  . LEU C 2 4   ? -52.916 -9.404  -46.736 1.00 48.51  ? 6   LEU K CA  1 
ATOM   3161 C C   . LEU C 2 4   ? -53.607 -10.234 -47.808 1.00 52.95  ? 6   LEU K C   1 
ATOM   3162 O O   . LEU C 2 4   ? -53.831 -11.432 -47.632 1.00 48.97  ? 6   LEU K O   1 
ATOM   3163 C CB  . LEU C 2 4   ? -51.432 -9.771  -46.673 1.00 46.46  ? 6   LEU K CB  1 
ATOM   3164 C CG  . LEU C 2 4   ? -50.595 -9.132  -45.565 1.00 48.97  ? 6   LEU K CG  1 
ATOM   3165 C CD1 . LEU C 2 4   ? -49.454 -10.048 -45.158 1.00 53.42  ? 6   LEU K CD1 1 
ATOM   3166 C CD2 . LEU C 2 4   ? -50.058 -7.790  -46.038 1.00 45.46  ? 6   LEU K CD2 1 
ATOM   3167 N N   . UNK C 2 5   ? -53.946 -9.589  -48.918 1.00 52.43  ? 7   UNK K N   1 
ATOM   3168 C CA  . UNK C 2 5   ? -54.580 -10.284 -50.032 1.00 51.65  ? 7   UNK K CA  1 
ATOM   3169 C C   . UNK C 2 5   ? -53.746 -10.135 -51.296 1.00 55.85  ? 7   UNK K C   1 
ATOM   3170 O O   . UNK C 2 5   ? -53.525 -9.022  -51.773 1.00 56.55  ? 7   UNK K O   1 
ATOM   3171 C CB  . UNK C 2 5   ? -55.997 -9.755  -50.264 1.00 52.55  ? 7   UNK K CB  1 
ATOM   3172 N N   . UNK C 2 6   ? -53.275 -11.258 -51.827 1.00 46.10  ? 8   UNK K N   1 
ATOM   3173 C CA  . UNK C 2 6   ? -52.468 -11.247 -53.040 1.00 48.72  ? 8   UNK K CA  1 
ATOM   3174 C C   . UNK C 2 6   ? -53.357 -11.488 -54.254 1.00 60.16  ? 8   UNK K C   1 
ATOM   3175 O O   . UNK C 2 6   ? -54.390 -12.151 -54.156 1.00 65.31  ? 8   UNK K O   1 
ATOM   3176 C CB  . UNK C 2 6   ? -51.363 -12.302 -52.967 1.00 46.81  ? 8   UNK K CB  1 
ATOM   3177 N N   . SER C 2 7   ? -52.951 -10.942 -55.395 1.00 53.56  ? 9   SER K N   1 
ATOM   3178 C CA  . SER C 2 7   ? -53.689 -11.111 -56.640 1.00 56.22  ? 9   SER K CA  1 
ATOM   3179 C C   . SER C 2 7   ? -52.773 -10.921 -57.843 1.00 58.39  ? 9   SER K C   1 
ATOM   3180 O O   . SER C 2 7   ? -51.654 -10.425 -57.710 1.00 55.09  ? 9   SER K O   1 
ATOM   3181 C CB  . SER C 2 7   ? -54.864 -10.132 -56.705 1.00 56.25  ? 9   SER K CB  1 
ATOM   3182 O OG  . SER C 2 7   ? -54.420 -8.793  -56.584 1.00 62.77  ? 9   SER K OG  1 
ATOM   3183 N N   . GLY C 2 8   ? -53.250 -11.326 -59.017 1.00 53.66  ? 10  GLY K N   1 
ATOM   3184 C CA  . GLY C 2 8   ? -52.523 -11.147 -60.257 1.00 56.52  ? 10  GLY K CA  1 
ATOM   3185 C C   . GLY C 2 8   ? -51.926 -12.412 -60.833 1.00 60.11  ? 10  GLY K C   1 
ATOM   3186 O O   . GLY C 2 8   ? -51.378 -12.366 -61.941 1.00 59.68  ? 10  GLY K O   1 
ATOM   3187 N N   . GLY C 2 9   ? -52.008 -13.534 -60.126 1.00 58.67  ? 11  GLY K N   1 
ATOM   3188 C CA  . GLY C 2 9   ? -51.463 -14.775 -60.633 1.00 65.89  ? 11  GLY K CA  1 
ATOM   3189 C C   . GLY C 2 9   ? -52.295 -15.357 -61.760 1.00 72.61  ? 11  GLY K C   1 
ATOM   3190 O O   . GLY C 2 9   ? -53.394 -14.899 -62.077 1.00 71.96  ? 11  GLY K O   1 
ATOM   3191 N N   . GLY C 2 10  ? -51.749 -16.398 -62.379 1.00 75.54  ? 12  GLY K N   1 
ATOM   3192 C CA  . GLY C 2 10  ? -52.437 -17.078 -63.461 1.00 71.79  ? 12  GLY K CA  1 
ATOM   3193 C C   . GLY C 2 10  ? -51.532 -17.877 -64.378 1.00 71.93  ? 12  GLY K C   1 
ATOM   3194 O O   . GLY C 2 10  ? -50.339 -18.029 -64.114 1.00 69.90  ? 12  GLY K O   1 
ATOM   3195 N N   . UNK C 2 11  ? -52.105 -18.386 -65.464 1.00 69.56  ? 13  UNK K N   1 
ATOM   3196 C CA  . UNK C 2 11  ? -51.358 -19.192 -66.425 1.00 68.56  ? 13  UNK K CA  1 
ATOM   3197 C C   . UNK C 2 11  ? -50.689 -18.317 -67.479 1.00 64.26  ? 13  UNK K C   1 
ATOM   3198 O O   . UNK C 2 11  ? -51.353 -17.559 -68.190 1.00 71.58  ? 13  UNK K O   1 
ATOM   3199 C CB  . UNK C 2 11  ? -52.278 -20.212 -67.098 1.00 61.88  ? 13  UNK K CB  1 
ATOM   3200 N N   . VAL C 2 12  ? -49.367 -18.423 -67.569 1.00 66.24  ? 14  VAL K N   1 
ATOM   3201 C CA  . VAL C 2 12  ? -48.587 -17.604 -68.487 1.00 66.66  ? 14  VAL K CA  1 
ATOM   3202 C C   . VAL C 2 12  ? -47.654 -18.497 -69.304 1.00 68.32  ? 14  VAL K C   1 
ATOM   3203 O O   . VAL C 2 12  ? -47.300 -19.593 -68.871 1.00 73.72  ? 14  VAL K O   1 
ATOM   3204 C CB  . VAL C 2 12  ? -47.793 -16.517 -67.725 1.00 65.39  ? 14  VAL K CB  1 
ATOM   3205 C CG1 . VAL C 2 12  ? -47.302 -15.442 -68.674 1.00 67.20  ? 14  VAL K CG1 1 
ATOM   3206 C CG2 . VAL C 2 12  ? -48.646 -15.897 -66.629 1.00 68.93  ? 14  VAL K CG2 1 
ATOM   3207 N N   . GLN C 2 13  ? -47.264 -18.029 -70.486 1.00 70.60  ? 15  GLN K N   1 
ATOM   3208 C CA  . GLN C 2 13  ? -46.301 -18.744 -71.317 1.00 74.12  ? 15  GLN K CA  1 
ATOM   3209 C C   . GLN C 2 13  ? -44.870 -18.457 -70.876 1.00 66.73  ? 15  GLN K C   1 
ATOM   3210 O O   . GLN C 2 13  ? -44.595 -17.431 -70.251 1.00 66.50  ? 15  GLN K O   1 
ATOM   3211 C CB  . GLN C 2 13  ? -46.480 -18.368 -72.789 1.00 76.35  ? 15  GLN K CB  1 
ATOM   3212 C CG  . GLN C 2 13  ? -47.843 -18.726 -73.358 1.00 81.54  ? 15  GLN K CG  1 
ATOM   3213 C CD  . GLN C 2 13  ? -47.957 -18.414 -74.837 1.00 85.80  ? 15  GLN K CD  1 
ATOM   3214 O OE1 . GLN C 2 13  ? -47.195 -17.611 -75.374 1.00 85.97  ? 15  GLN K OE1 1 
ATOM   3215 N NE2 . GLN C 2 13  ? -48.910 -19.054 -75.505 1.00 82.97  ? 15  GLN K NE2 1 
ATOM   3216 N N   . UNK C 2 14  ? -43.961 -19.368 -71.208 1.00 63.70  ? 16  UNK K N   1 
ATOM   3217 C CA  . UNK C 2 14  ? -42.555 -19.218 -70.852 1.00 64.62  ? 16  UNK K CA  1 
ATOM   3218 C C   . UNK C 2 14  ? -41.921 -18.049 -71.597 1.00 68.31  ? 16  UNK K C   1 
ATOM   3219 O O   . UNK C 2 14  ? -41.907 -18.017 -72.829 1.00 77.79  ? 16  UNK K O   1 
ATOM   3220 C CB  . UNK C 2 14  ? -41.786 -20.509 -71.145 1.00 61.69  ? 16  UNK K CB  1 
ATOM   3221 N N   . GLY C 2 15  ? -41.399 -17.089 -70.840 1.00 66.77  ? 17  GLY K N   1 
ATOM   3222 C CA  . GLY C 2 15  ? -40.728 -15.939 -71.416 1.00 56.94  ? 17  GLY K CA  1 
ATOM   3223 C C   . GLY C 2 15  ? -41.550 -14.666 -71.372 1.00 61.53  ? 17  GLY K C   1 
ATOM   3224 O O   . GLY C 2 15  ? -41.142 -13.638 -71.911 1.00 62.79  ? 17  GLY K O   1 
ATOM   3225 N N   . UNK C 2 16  ? -42.710 -14.730 -70.725 1.00 62.01  ? 18  UNK K N   1 
ATOM   3226 C CA  . UNK C 2 16  ? -43.602 -13.578 -70.649 1.00 64.44  ? 18  UNK K CA  1 
ATOM   3227 C C   . UNK C 2 16  ? -43.490 -12.866 -69.304 1.00 61.45  ? 18  UNK K C   1 
ATOM   3228 O O   . UNK C 2 16  ? -42.523 -13.061 -68.566 1.00 54.45  ? 18  UNK K O   1 
ATOM   3229 C CB  . UNK C 2 16  ? -45.048 -14.007 -70.894 1.00 70.61  ? 18  UNK K CB  1 
ATOM   3230 N N   . SER C 2 17  ? -44.483 -12.040 -68.989 1.00 59.51  ? 19  SER K N   1 
ATOM   3231 C CA  . SER C 2 17  ? -44.425 -11.208 -67.792 1.00 57.19  ? 19  SER K CA  1 
ATOM   3232 C C   . SER C 2 17  ? -45.670 -11.326 -66.917 1.00 57.22  ? 19  SER K C   1 
ATOM   3233 O O   . SER C 2 17  ? -46.683 -11.898 -67.321 1.00 60.79  ? 19  SER K O   1 
ATOM   3234 C CB  . SER C 2 17  ? -44.210 -9.743  -68.179 1.00 60.00  ? 19  SER K CB  1 
ATOM   3235 O OG  . SER C 2 17  ? -42.932 -9.556  -68.764 1.00 65.82  ? 19  SER K OG  1 
ATOM   3236 N N   . LEU C 2 18  ? -45.569 -10.772 -65.712 1.00 59.88  ? 20  LEU K N   1 
ATOM   3237 C CA  . LEU C 2 18  ? -46.671 -10.704 -64.756 1.00 57.62  ? 20  LEU K CA  1 
ATOM   3238 C C   . LEU C 2 18  ? -46.476 -9.545  -63.787 1.00 53.82  ? 20  LEU K C   1 
ATOM   3239 O O   . LEU C 2 18  ? -45.351 -9.138  -63.516 1.00 58.69  ? 20  LEU K O   1 
ATOM   3240 C CB  . LEU C 2 18  ? -46.789 -12.013 -63.977 1.00 60.46  ? 20  LEU K CB  1 
ATOM   3241 C CG  . LEU C 2 18  ? -47.649 -13.140 -64.533 1.00 59.97  ? 20  LEU K CG  1 
ATOM   3242 C CD1 . LEU C 2 18  ? -47.746 -14.251 -63.511 1.00 61.63  ? 20  LEU K CD1 1 
ATOM   3243 C CD2 . LEU C 2 18  ? -49.036 -12.596 -64.836 1.00 66.88  ? 20  LEU K CD2 1 
ATOM   3244 N N   . UNK C 2 19  ? -47.575 -9.021  -63.259 1.00 54.15  ? 21  UNK K N   1 
ATOM   3245 C CA  . UNK C 2 19  ? -47.500 -7.968  -62.257 1.00 52.91  ? 21  UNK K CA  1 
ATOM   3246 C C   . UNK C 2 19  ? -48.354 -8.346  -61.057 1.00 56.10  ? 21  UNK K C   1 
ATOM   3247 O O   . UNK C 2 19  ? -49.507 -7.924  -60.947 1.00 61.35  ? 21  UNK K O   1 
ATOM   3248 C CB  . UNK C 2 19  ? -47.955 -6.630  -62.839 1.00 50.91  ? 21  UNK K CB  1 
ATOM   3249 N N   . LEU C 2 20  ? -47.789 -9.147  -60.160 1.00 58.83  ? 22  LEU K N   1 
ATOM   3250 C CA  . LEU C 2 20  ? -48.507 -9.550  -58.958 1.00 50.14  ? 22  LEU K CA  1 
ATOM   3251 C C   . LEU C 2 20  ? -48.625 -8.365  -58.010 1.00 49.36  ? 22  LEU K C   1 
ATOM   3252 O O   . LEU C 2 20  ? -47.731 -7.527  -57.939 1.00 52.75  ? 22  LEU K O   1 
ATOM   3253 C CB  . LEU C 2 20  ? -47.804 -10.722 -58.265 1.00 50.10  ? 22  LEU K CB  1 
ATOM   3254 C CG  . LEU C 2 20  ? -48.013 -12.160 -58.762 1.00 50.40  ? 22  LEU K CG  1 
ATOM   3255 C CD1 . LEU C 2 20  ? -48.130 -12.262 -60.280 1.00 50.82  ? 22  LEU K CD1 1 
ATOM   3256 C CD2 . LEU C 2 20  ? -46.895 -13.058 -58.251 1.00 49.19  ? 22  LEU K CD2 1 
ATOM   3257 N N   . SER C 2 21  ? -49.732 -8.302  -57.278 1.00 52.04  ? 23  SER K N   1 
ATOM   3258 C CA  . SER C 2 21  ? -49.963 -7.245  -56.310 1.00 48.08  ? 23  SER K CA  1 
ATOM   3259 C C   . SER C 2 21  ? -50.390 -7.856  -54.986 1.00 50.50  ? 23  SER K C   1 
ATOM   3260 O O   . SER C 2 21  ? -50.906 -8.975  -54.929 1.00 54.28  ? 23  SER K O   1 
ATOM   3261 C CB  . SER C 2 21  ? -51.031 -6.257  -56.799 1.00 47.93  ? 23  SER K CB  1 
ATOM   3262 O OG  . SER C 2 21  ? -51.424 -5.377  -55.759 1.00 55.91  ? 23  SER K OG  1 
ATOM   3263 N N   . CYS C 2 22  ? -50.152 -7.112  -53.914 1.00 50.42  ? 24  CYS K N   1 
ATOM   3264 C CA  . CYS C 2 22  ? -50.641 -7.497  -52.600 1.00 51.22  ? 24  CYS K CA  1 
ATOM   3265 C C   . CYS C 2 22  ? -51.182 -6.274  -51.878 1.00 53.90  ? 24  CYS K C   1 
ATOM   3266 O O   . CYS C 2 22  ? -50.468 -5.287  -51.677 1.00 48.55  ? 24  CYS K O   1 
ATOM   3267 C CB  . CYS C 2 22  ? -49.543 -8.159  -51.771 1.00 52.24  ? 24  CYS K CB  1 
ATOM   3268 S SG  . CYS C 2 22  ? -50.091 -8.653  -50.121 1.00 50.18  ? 24  CYS K SG  1 
ATOM   3269 N N   . UNK C 2 23  ? -52.453 -6.348  -51.500 1.00 53.88  ? 25  UNK K N   1 
ATOM   3270 C CA  . UNK C 2 23  ? -53.104 -5.275  -50.765 1.00 53.16  ? 25  UNK K CA  1 
ATOM   3271 C C   . UNK C 2 23  ? -53.129 -5.580  -49.272 1.00 51.99  ? 25  UNK K C   1 
ATOM   3272 O O   . UNK C 2 23  ? -53.392 -6.713  -48.850 1.00 55.64  ? 25  UNK K O   1 
ATOM   3273 C CB  . UNK C 2 23  ? -54.527 -5.056  -51.283 1.00 53.90  ? 25  UNK K CB  1 
ATOM   3274 N N   . ALA C 2 24  ? -52.848 -4.554  -48.476 1.00 54.53  ? 26  ALA K N   1 
ATOM   3275 C CA  . ALA C 2 24  ? -52.854 -4.674  -47.024 1.00 58.10  ? 26  ALA K CA  1 
ATOM   3276 C C   . ALA C 2 24  ? -54.091 -4.001  -46.443 1.00 64.52  ? 26  ALA K C   1 
ATOM   3277 O O   . ALA C 2 24  ? -54.514 -2.945  -46.915 1.00 66.17  ? 26  ALA K O   1 
ATOM   3278 C CB  . ALA C 2 24  ? -51.590 -4.069  -46.435 1.00 53.32  ? 26  ALA K CB  1 
ATOM   3279 N N   . UNK C 2 25  ? -54.667 -4.618  -45.417 1.00 58.62  ? 27  UNK K N   1 
ATOM   3280 C CA  . UNK C 2 25  ? -55.864 -4.092  -44.779 1.00 55.07  ? 27  UNK K CA  1 
ATOM   3281 C C   . UNK C 2 25  ? -55.741 -4.140  -43.260 1.00 62.96  ? 27  UNK K C   1 
ATOM   3282 O O   . UNK C 2 25  ? -55.034 -4.996  -42.709 1.00 61.49  ? 27  UNK K O   1 
ATOM   3283 C CB  . UNK C 2 25  ? -57.092 -4.866  -45.238 1.00 60.87  ? 27  UNK K CB  1 
ATOM   3284 N N   . UNK C 2 26  ? -56.438 -3.201  -42.615 1.00 63.42  ? 28  UNK K N   1 
ATOM   3285 C CA  . UNK C 2 26  ? -56.514 -3.039  -41.159 1.00 62.60  ? 28  UNK K CA  1 
ATOM   3286 C C   . UNK C 2 26  ? -55.250 -2.429  -40.554 1.00 56.08  ? 28  UNK K C   1 
ATOM   3287 O O   . UNK C 2 26  ? -55.205 -2.189  -39.346 1.00 60.68  ? 28  UNK K O   1 
ATOM   3288 C CB  . UNK C 2 26  ? -56.827 -4.371  -40.472 1.00 66.71  ? 28  UNK K CB  1 
ATOM   3289 N N   . UNK C 2 27  ? -54.244 -2.162  -41.381 1.00 60.53  ? 29  UNK K N   1 
ATOM   3290 C CA  . UNK C 2 27  ? -53.031 -1.497  -40.911 1.00 59.03  ? 29  UNK K CA  1 
ATOM   3291 C C   . UNK C 2 27  ? -52.228 -0.900  -42.062 1.00 61.61  ? 29  UNK K C   1 
ATOM   3292 O O   . UNK C 2 27  ? -52.246 -1.417  -43.181 1.00 52.60  ? 29  UNK K O   1 
ATOM   3293 C CB  . UNK C 2 27  ? -52.156 -2.474  -40.122 1.00 54.88  ? 29  UNK K CB  1 
ATOM   3294 N N   . UNK C 2 28  ? -51.523 0.191   -41.779 1.00 64.01  ? 30  UNK K N   1 
ATOM   3295 C CA  . UNK C 2 28  ? -50.663 0.828   -42.770 1.00 60.48  ? 30  UNK K CA  1 
ATOM   3296 C C   . UNK C 2 28  ? -49.382 0.021   -42.952 1.00 59.07  ? 30  UNK K C   1 
ATOM   3297 O O   . UNK C 2 28  ? -48.866 -0.561  -41.998 1.00 55.44  ? 30  UNK K O   1 
ATOM   3298 C CB  . UNK C 2 28  ? -50.333 2.263   -42.355 1.00 54.77  ? 30  UNK K CB  1 
ATOM   3299 N N   . UNK C 2 29  ? -48.873 -0.009  -44.179 1.00 56.21  ? 31  UNK K N   1 
ATOM   3300 C CA  . UNK C 2 29  ? -47.671 -0.776  -44.488 1.00 58.30  ? 31  UNK K CA  1 
ATOM   3301 C C   . UNK C 2 29  ? -46.499 0.133   -44.849 1.00 61.39  ? 31  UNK K C   1 
ATOM   3302 O O   . UNK C 2 29  ? -45.544 -0.304  -45.493 1.00 64.26  ? 31  UNK K O   1 
ATOM   3303 C CB  . UNK C 2 29  ? -47.946 -1.754  -45.633 1.00 45.90  ? 31  UNK K CB  1 
ATOM   3304 N N   . UNK C 2 30  ? -46.572 1.390   -44.424 1.00 53.62  ? 32  UNK K N   1 
ATOM   3305 C CA  . UNK C 2 30  ? -45.578 2.388   -44.807 1.00 53.23  ? 32  UNK K CA  1 
ATOM   3306 C C   . UNK C 2 30  ? -44.307 2.311   -43.964 1.00 54.55  ? 32  UNK K C   1 
ATOM   3307 O O   . UNK C 2 30  ? -43.235 2.714   -44.420 1.00 58.08  ? 32  UNK K O   1 
ATOM   3308 C CB  . UNK C 2 30  ? -46.176 3.794   -44.708 1.00 56.64  ? 32  UNK K CB  1 
ATOM   3309 N N   . UNK C 2 31  ? -44.423 1.796   -42.744 1.00 52.59  ? 33  UNK K N   1 
ATOM   3310 C CA  . UNK C 2 31  ? -43.294 1.774   -41.819 1.00 51.83  ? 33  UNK K CA  1 
ATOM   3311 C C   . UNK C 2 31  ? -42.649 0.395   -41.709 1.00 48.43  ? 33  UNK K C   1 
ATOM   3312 O O   . UNK C 2 31  ? -41.855 0.151   -40.798 1.00 45.62  ? 33  UNK K O   1 
ATOM   3313 C CB  . UNK C 2 31  ? -43.739 2.246   -40.432 1.00 52.46  ? 33  UNK K CB  1 
ATOM   3314 N N   . UNK C 2 32  ? -42.983 -0.500  -42.633 1.00 43.50  ? 34  UNK K N   1 
ATOM   3315 C CA  . UNK C 2 32  ? -42.498 -1.875  -42.560 1.00 40.75  ? 34  UNK K CA  1 
ATOM   3316 C C   . UNK C 2 32  ? -42.134 -2.425  -43.934 1.00 45.52  ? 34  UNK K C   1 
ATOM   3317 O O   . UNK C 2 32  ? -42.730 -2.058  -44.948 1.00 44.77  ? 34  UNK K O   1 
ATOM   3318 C CB  . UNK C 2 32  ? -43.546 -2.775  -41.902 1.00 45.99  ? 34  UNK K CB  1 
ATOM   3319 N N   . UNK C 2 33  ? -41.146 -3.313  -43.956 1.00 45.81  ? 35  UNK K N   1 
ATOM   3320 C CA  . UNK C 2 33  ? -40.746 -3.983  -45.184 1.00 37.37  ? 35  UNK K CA  1 
ATOM   3321 C C   . UNK C 2 33  ? -41.778 -5.033  -45.582 1.00 31.98  ? 35  UNK K C   1 
ATOM   3322 O O   . UNK C 2 33  ? -42.363 -5.700  -44.728 1.00 36.16  ? 35  UNK K O   1 
ATOM   3323 C CB  . UNK C 2 33  ? -39.371 -4.633  -45.021 1.00 35.56  ? 35  UNK K CB  1 
ATOM   3324 N N   . UNK C 2 34  ? -41.998 -5.169  -46.885 1.00 35.19  ? 36  UNK K N   1 
ATOM   3325 C CA  . UNK C 2 34  ? -42.890 -6.194  -47.409 1.00 35.03  ? 36  UNK K CA  1 
ATOM   3326 C C   . UNK C 2 34  ? -42.079 -7.190  -48.229 1.00 36.48  ? 36  UNK K C   1 
ATOM   3327 O O   . UNK C 2 34  ? -41.278 -6.792  -49.079 1.00 37.06  ? 36  UNK K O   1 
ATOM   3328 C CB  . UNK C 2 34  ? -43.999 -5.569  -48.256 1.00 34.78  ? 36  UNK K CB  1 
ATOM   3329 N N   . UNK C 2 35  ? -42.277 -8.481  -47.977 1.00 39.99  ? 37  UNK K N   1 
ATOM   3330 C CA  . UNK C 2 35  ? -41.446 -9.498  -48.611 1.00 37.00  ? 37  UNK K CA  1 
ATOM   3331 C C   . UNK C 2 35  ? -42.259 -10.554 -49.352 1.00 39.02  ? 37  UNK K C   1 
ATOM   3332 O O   . UNK C 2 35  ? -43.224 -11.106 -48.829 1.00 46.26  ? 37  UNK K O   1 
ATOM   3333 C CB  . UNK C 2 35  ? -40.557 -10.174 -47.567 1.00 29.28  ? 37  UNK K CB  1 
ATOM   3334 N N   . TRP C 2 36  ? -41.850 -10.827 -50.585 1.00 38.28  ? 38  TRP K N   1 
ATOM   3335 C CA  . TRP C 2 36  ? -42.436 -11.903 -51.369 1.00 38.95  ? 38  TRP K CA  1 
ATOM   3336 C C   . TRP C 2 36  ? -41.618 -13.177 -51.225 1.00 41.00  ? 38  TRP K C   1 
ATOM   3337 O O   . TRP C 2 36  ? -40.391 -13.157 -51.373 1.00 41.66  ? 38  TRP K O   1 
ATOM   3338 C CB  . TRP C 2 36  ? -42.527 -11.523 -52.847 1.00 40.20  ? 38  TRP K CB  1 
ATOM   3339 C CG  . TRP C 2 36  ? -43.567 -10.502 -53.161 1.00 42.76  ? 38  TRP K CG  1 
ATOM   3340 C CD1 . TRP C 2 36  ? -43.393 -9.152  -53.224 1.00 43.59  ? 38  TRP K CD1 1 
ATOM   3341 C CD2 . TRP C 2 36  ? -44.946 -10.746 -53.466 1.00 43.08  ? 38  TRP K CD2 1 
ATOM   3342 N NE1 . TRP C 2 36  ? -44.578 -8.538  -53.548 1.00 40.82  ? 38  TRP K NE1 1 
ATOM   3343 C CE2 . TRP C 2 36  ? -45.547 -9.494  -53.702 1.00 47.37  ? 38  TRP K CE2 1 
ATOM   3344 C CE3 . TRP C 2 36  ? -45.729 -11.900 -53.562 1.00 42.75  ? 38  TRP K CE3 1 
ATOM   3345 C CZ2 . TRP C 2 36  ? -46.895 -9.363  -54.026 1.00 51.14  ? 38  TRP K CZ2 1 
ATOM   3346 C CZ3 . TRP C 2 36  ? -47.069 -11.768 -53.885 1.00 44.89  ? 38  TRP K CZ3 1 
ATOM   3347 C CH2 . TRP C 2 36  ? -47.638 -10.509 -54.113 1.00 46.87  ? 38  TRP K CH2 1 
ATOM   3348 N N   . UNK C 2 37  ? -42.316 -14.272 -50.937 1.00 34.43  ? 39  UNK K N   1 
ATOM   3349 C CA  . UNK C 2 37  ? -41.733 -15.606 -50.907 1.00 43.09  ? 39  UNK K CA  1 
ATOM   3350 C C   . UNK C 2 37  ? -42.566 -16.499 -51.822 1.00 41.33  ? 39  UNK K C   1 
ATOM   3351 O O   . UNK C 2 37  ? -43.648 -16.093 -52.242 1.00 44.20  ? 39  UNK K O   1 
ATOM   3352 C CB  . UNK C 2 37  ? -41.702 -16.160 -49.481 1.00 43.79  ? 39  UNK K CB  1 
ATOM   3353 N N   . ARG C 2 38  ? -42.082 -17.697 -52.134 1.00 41.04  ? 40  ARG K N   1 
ATOM   3354 C CA  . ARG C 2 38  ? -42.849 -18.604 -52.986 1.00 50.98  ? 40  ARG K CA  1 
ATOM   3355 C C   . ARG C 2 38  ? -42.673 -20.060 -52.570 1.00 50.11  ? 40  ARG K C   1 
ATOM   3356 O O   . ARG C 2 38  ? -41.650 -20.437 -51.998 1.00 53.47  ? 40  ARG K O   1 
ATOM   3357 C CB  . ARG C 2 38  ? -42.457 -18.420 -54.454 1.00 44.67  ? 40  ARG K CB  1 
ATOM   3358 C CG  . ARG C 2 38  ? -41.080 -18.945 -54.823 1.00 50.62  ? 40  ARG K CG  1 
ATOM   3359 C CD  . ARG C 2 38  ? -40.729 -18.550 -56.249 1.00 48.32  ? 40  ARG K CD  1 
ATOM   3360 N NE  . ARG C 2 38  ? -39.371 -18.933 -56.614 1.00 50.52  ? 40  ARG K NE  1 
ATOM   3361 C CZ  . ARG C 2 38  ? -38.825 -18.705 -57.801 1.00 50.76  ? 40  ARG K CZ  1 
ATOM   3362 N NH1 . ARG C 2 38  ? -39.493 -18.089 -58.762 1.00 45.51  ? 40  ARG K NH1 1 
ATOM   3363 N NH2 . ARG C 2 38  ? -37.577 -19.105 -58.028 1.00 48.87  ? 40  ARG K NH2 1 
ATOM   3364 N N   . GLN C 2 39  ? -43.682 -20.875 -52.861 1.00 51.84  ? 41  GLN K N   1 
ATOM   3365 C CA  . GLN C 2 39  ? -43.655 -22.277 -52.459 1.00 51.67  ? 41  GLN K CA  1 
ATOM   3366 C C   . GLN C 2 39  ? -44.194 -23.211 -53.538 1.00 56.48  ? 41  GLN K C   1 
ATOM   3367 O O   . GLN C 2 39  ? -45.261 -22.975 -54.105 1.00 59.50  ? 41  GLN K O   1 
ATOM   3368 C CB  . GLN C 2 39  ? -44.455 -22.473 -51.169 1.00 46.43  ? 41  GLN K CB  1 
ATOM   3369 C CG  . GLN C 2 39  ? -44.141 -23.767 -50.435 1.00 51.66  ? 41  GLN K CG  1 
ATOM   3370 C CD  . GLN C 2 39  ? -44.940 -23.920 -49.156 1.00 53.09  ? 41  GLN K CD  1 
ATOM   3371 O OE1 . GLN C 2 39  ? -45.855 -23.143 -48.885 1.00 56.93  ? 41  GLN K OE1 1 
ATOM   3372 N NE2 . GLN C 2 39  ? -44.592 -24.923 -48.358 1.00 50.79  ? 41  GLN K NE2 1 
ATOM   3373 N N   . UNK C 2 40  ? -43.438 -24.267 -53.821 1.00 60.64  ? 42  UNK K N   1 
ATOM   3374 C CA  . UNK C 2 40  ? -43.890 -25.331 -54.706 1.00 65.45  ? 42  UNK K CA  1 
ATOM   3375 C C   . UNK C 2 40  ? -44.567 -26.376 -53.824 1.00 66.97  ? 42  UNK K C   1 
ATOM   3376 O O   . UNK C 2 40  ? -44.168 -26.521 -52.668 1.00 69.29  ? 42  UNK K O   1 
ATOM   3377 C CB  . UNK C 2 40  ? -42.720 -25.929 -55.493 1.00 68.92  ? 42  UNK K CB  1 
ATOM   3378 N N   . PRO C 2 41  ? -45.579 -27.088 -54.355 1.00 70.20  ? 43  PRO K N   1 
ATOM   3379 C CA  . PRO C 2 41  ? -46.383 -28.066 -53.606 1.00 74.69  ? 43  PRO K CA  1 
ATOM   3380 C C   . PRO C 2 41  ? -45.615 -28.933 -52.604 1.00 74.41  ? 43  PRO K C   1 
ATOM   3381 O O   . PRO C 2 41  ? -45.989 -28.974 -51.432 1.00 79.35  ? 43  PRO K O   1 
ATOM   3382 C CB  . PRO C 2 41  ? -46.974 -28.934 -54.717 1.00 66.21  ? 43  PRO K CB  1 
ATOM   3383 C CG  . PRO C 2 41  ? -47.148 -27.986 -55.845 1.00 70.48  ? 43  PRO K CG  1 
ATOM   3384 C CD  . PRO C 2 41  ? -45.983 -27.032 -55.773 1.00 73.02  ? 43  PRO K CD  1 
ATOM   3385 N N   . GLY C 2 42  ? -44.558 -29.602 -53.052 1.00 69.40  ? 44  GLY K N   1 
ATOM   3386 C CA  . GLY C 2 42  ? -43.793 -30.470 -52.174 1.00 75.10  ? 44  GLY K CA  1 
ATOM   3387 C C   . GLY C 2 42  ? -42.550 -29.858 -51.555 1.00 73.62  ? 44  GLY K C   1 
ATOM   3388 O O   . GLY C 2 42  ? -41.704 -30.574 -51.019 1.00 71.43  ? 44  GLY K O   1 
ATOM   3389 N N   . UNK C 2 43  ? -42.439 -28.535 -51.615 1.00 71.58  ? 45  UNK K N   1 
ATOM   3390 C CA  . UNK C 2 43  ? -41.267 -27.850 -51.079 1.00 69.36  ? 45  UNK K CA  1 
ATOM   3391 C C   . UNK C 2 43  ? -41.627 -26.833 -49.998 1.00 62.45  ? 45  UNK K C   1 
ATOM   3392 O O   . UNK C 2 43  ? -42.791 -26.682 -49.625 1.00 60.99  ? 45  UNK K O   1 
ATOM   3393 C CB  . UNK C 2 43  ? -40.500 -27.155 -52.206 1.00 66.55  ? 45  UNK K CB  1 
ATOM   3394 N N   . UNK C 2 44  ? -40.609 -26.137 -49.499 1.00 60.48  ? 46  UNK K N   1 
ATOM   3395 C CA  . UNK C 2 44  ? -40.793 -25.123 -48.468 1.00 53.07  ? 46  UNK K CA  1 
ATOM   3396 C C   . UNK C 2 44  ? -40.801 -23.727 -49.082 1.00 52.46  ? 46  UNK K C   1 
ATOM   3397 O O   . UNK C 2 44  ? -40.433 -23.551 -50.245 1.00 53.52  ? 46  UNK K O   1 
ATOM   3398 C CB  . UNK C 2 44  ? -39.694 -25.228 -47.408 1.00 54.20  ? 46  UNK K CB  1 
ATOM   3399 N N   . ARG C 2 45  ? -41.214 -22.738 -48.297 1.00 53.00  ? 47  ARG K N   1 
ATOM   3400 C CA  . ARG C 2 45  ? -41.291 -21.362 -48.776 1.00 48.51  ? 47  ARG K CA  1 
ATOM   3401 C C   . ARG C 2 45  ? -39.911 -20.725 -48.877 1.00 51.38  ? 47  ARG K C   1 
ATOM   3402 O O   . ARG C 2 45  ? -39.228 -20.542 -47.869 1.00 49.22  ? 47  ARG K O   1 
ATOM   3403 C CB  . ARG C 2 45  ? -42.185 -20.523 -47.860 1.00 50.31  ? 47  ARG K CB  1 
ATOM   3404 C CG  . ARG C 2 45  ? -43.640 -20.959 -47.849 1.00 54.98  ? 47  ARG K CG  1 
ATOM   3405 C CD  . ARG C 2 45  ? -44.520 -19.957 -47.117 1.00 54.50  ? 47  ARG K CD  1 
ATOM   3406 N NE  . ARG C 2 45  ? -45.785 -20.552 -46.699 1.00 63.97  ? 47  ARG K NE  1 
ATOM   3407 C CZ  . ARG C 2 45  ? -46.757 -19.895 -46.082 1.00 57.00  ? 47  ARG K CZ  1 
ATOM   3408 N NH1 . ARG C 2 45  ? -46.649 -18.609 -45.794 1.00 51.10  ? 47  ARG K NH1 1 
ATOM   3409 N NH2 . ARG C 2 45  ? -47.865 -20.547 -45.740 1.00 58.75  ? 47  ARG K NH2 1 
ATOM   3410 N N   . GLU C 2 46  ? -39.504 -20.390 -50.096 1.00 48.94  ? 48  GLU K N   1 
ATOM   3411 C CA  . GLU C 2 46  ? -38.211 -19.754 -50.316 1.00 52.06  ? 48  GLU K CA  1 
ATOM   3412 C C   . GLU C 2 46  ? -38.409 -18.256 -50.520 1.00 43.60  ? 48  GLU K C   1 
ATOM   3413 O O   . GLU C 2 46  ? -39.410 -17.826 -51.093 1.00 39.09  ? 48  GLU K O   1 
ATOM   3414 C CB  . GLU C 2 46  ? -37.489 -20.371 -51.519 1.00 52.45  ? 48  GLU K CB  1 
ATOM   3415 C CG  . GLU C 2 46  ? -38.088 -20.015 -52.872 1.00 56.29  ? 48  GLU K CG  1 
ATOM   3416 C CD  . GLU C 2 46  ? -37.223 -20.470 -54.028 1.00 64.04  ? 48  GLU K CD  1 
ATOM   3417 O OE1 . GLU C 2 46  ? -36.967 -21.687 -54.138 1.00 66.07  ? 48  GLU K OE1 1 
ATOM   3418 O OE2 . GLU C 2 46  ? -36.787 -19.609 -54.820 1.00 56.08  ? 48  GLU K OE2 1 
ATOM   3419 N N   . UNK C 2 47  ? -37.458 -17.463 -50.039 1.00 43.01  ? 49  UNK K N   1 
ATOM   3420 C CA  . UNK C 2 47  ? -37.519 -16.017 -50.207 1.00 38.77  ? 49  UNK K CA  1 
ATOM   3421 C C   . UNK C 2 47  ? -37.382 -15.647 -51.679 1.00 41.61  ? 49  UNK K C   1 
ATOM   3422 O O   . UNK C 2 47  ? -36.586 -16.242 -52.407 1.00 38.23  ? 49  UNK K O   1 
ATOM   3423 C CB  . UNK C 2 47  ? -36.429 -15.330 -49.382 1.00 32.09  ? 49  UNK K CB  1 
ATOM   3424 N N   . VAL C 2 48  ? -38.170 -14.670 -52.116 1.00 40.57  ? 50  VAL K N   1 
ATOM   3425 C CA  . VAL C 2 48  ? -38.097 -14.194 -53.491 1.00 35.16  ? 50  VAL K CA  1 
ATOM   3426 C C   . VAL C 2 48  ? -37.506 -12.795 -53.521 1.00 39.34  ? 50  VAL K C   1 
ATOM   3427 O O   . VAL C 2 48  ? -36.514 -12.546 -54.205 1.00 38.14  ? 50  VAL K O   1 
ATOM   3428 C CB  . VAL C 2 48  ? -39.477 -14.210 -54.168 1.00 35.62  ? 50  VAL K CB  1 
ATOM   3429 C CG1 . VAL C 2 48  ? -39.390 -13.621 -55.567 1.00 41.54  ? 50  VAL K CG1 1 
ATOM   3430 C CG2 . VAL C 2 48  ? -40.028 -15.619 -54.207 1.00 38.99  ? 50  VAL K CG2 1 
ATOM   3431 N N   . UNK C 2 49  ? -38.122 -11.883 -52.775 1.00 34.55  ? 51  UNK K N   1 
ATOM   3432 C CA  . UNK C 2 49  ? -37.686 -10.489 -52.789 1.00 33.59  ? 51  UNK K CA  1 
ATOM   3433 C C   . UNK C 2 49  ? -38.182 -9.720  -51.573 1.00 35.03  ? 51  UNK K C   1 
ATOM   3434 O O   . UNK C 2 49  ? -39.073 -10.174 -50.861 1.00 39.25  ? 51  UNK K O   1 
ATOM   3435 C CB  . UNK C 2 49  ? -38.158 -9.796  -54.070 1.00 34.16  ? 51  UNK K CB  1 
ATOM   3436 N N   . UNK C 2 50  ? -37.604 -8.547  -51.345 1.00 28.98  ? 52  UNK K N   1 
ATOM   3437 C CA  . UNK C 2 50  ? -38.002 -7.706  -50.224 1.00 36.94  ? 52  UNK K CA  1 
ATOM   3438 C C   . UNK C 2 50  ? -37.915 -6.234  -50.594 1.00 37.60  ? 52  UNK K C   1 
ATOM   3439 O O   . UNK C 2 50  ? -36.929 -5.790  -51.186 1.00 36.11  ? 52  UNK K O   1 
ATOM   3440 C CB  . UNK C 2 50  ? -37.131 -7.992  -49.002 1.00 37.38  ? 52  UNK K CB  1 
ATOM   3441 N N   . UNK C 2 51  ? -38.955 -5.484  -50.249 1.00 36.73  ? 53  UNK K N   1 
ATOM   3442 C CA  . UNK C 2 51  ? -38.934 -4.038  -50.381 1.00 39.72  ? 53  UNK K CA  1 
ATOM   3443 C C   . UNK C 2 51  ? -39.027 -3.425  -48.992 1.00 39.96  ? 53  UNK K C   1 
ATOM   3444 O O   . UNK C 2 51  ? -40.044 -3.565  -48.311 1.00 40.43  ? 53  UNK K O   1 
ATOM   3445 C CB  . UNK C 2 51  ? -40.080 -3.549  -51.268 1.00 40.36  ? 53  UNK K CB  1 
ATOM   3446 N N   . UNK C 2 52  ? -37.960 -2.758  -48.567 1.00 36.74  ? 54  UNK K N   1 
ATOM   3447 C CA  . UNK C 2 52  ? -37.958 -2.083  -47.276 1.00 47.25  ? 54  UNK K CA  1 
ATOM   3448 C C   . UNK C 2 52  ? -38.757 -0.789  -47.372 1.00 43.91  ? 54  UNK K C   1 
ATOM   3449 O O   . UNK C 2 52  ? -39.448 -0.553  -48.365 1.00 43.85  ? 54  UNK K O   1 
ATOM   3450 C CB  . UNK C 2 52  ? -36.527 -1.802  -46.816 1.00 45.25  ? 54  UNK K CB  1 
ATOM   3451 N N   . UNK C 2 53  ? -38.666 0.044   -46.341 1.00 46.09  ? 55  UNK K N   1 
ATOM   3452 C CA  . UNK C 2 53  ? -39.331 1.340   -46.357 1.00 48.91  ? 55  UNK K CA  1 
ATOM   3453 C C   . UNK C 2 53  ? -38.766 2.184   -47.493 1.00 52.56  ? 55  UNK K C   1 
ATOM   3454 O O   . UNK C 2 53  ? -37.684 1.888   -48.003 1.00 49.44  ? 55  UNK K O   1 
ATOM   3455 C CB  . UNK C 2 53  ? -39.159 2.058   -45.016 1.00 47.80  ? 55  UNK K CB  1 
ATOM   3456 N N   . UNK C 2 54  ? -39.500 3.215   -47.898 1.00 53.35  ? 56  UNK K N   1 
ATOM   3457 C CA  . UNK C 2 54  ? -39.069 4.070   -48.998 1.00 50.58  ? 56  UNK K CA  1 
ATOM   3458 C C   . UNK C 2 54  ? -37.683 4.640   -48.708 1.00 52.61  ? 56  UNK K C   1 
ATOM   3459 O O   . UNK C 2 54  ? -37.409 5.052   -47.578 1.00 54.55  ? 56  UNK K O   1 
ATOM   3460 C CB  . UNK C 2 54  ? -40.074 5.198   -49.235 1.00 56.52  ? 56  UNK K CB  1 
ATOM   3461 N N   . UNK C 2 55  ? -36.825 4.627   -49.729 1.00 51.59  ? 57  UNK K N   1 
ATOM   3462 C CA  . UNK C 2 55  ? -35.428 5.068   -49.649 1.00 48.92  ? 57  UNK K CA  1 
ATOM   3463 C C   . UNK C 2 55  ? -34.549 4.111   -48.838 1.00 52.24  ? 57  UNK K C   1 
ATOM   3464 O O   . UNK C 2 55  ? -33.458 4.486   -48.406 1.00 56.21  ? 57  UNK K O   1 
ATOM   3465 C CB  . UNK C 2 55  ? -35.330 6.485   -49.070 1.00 53.53  ? 57  UNK K CB  1 
ATOM   3466 N N   . UNK C 2 56  ? -35.019 2.883   -48.640 1.00 49.24  ? 58  UNK K N   1 
ATOM   3467 C CA  . UNK C 2 56  ? -34.218 1.855   -47.980 1.00 49.05  ? 58  UNK K CA  1 
ATOM   3468 C C   . UNK C 2 56  ? -34.002 0.687   -48.940 1.00 50.66  ? 58  UNK K C   1 
ATOM   3469 O O   . UNK C 2 56  ? -33.499 -0.372  -48.554 1.00 51.98  ? 58  UNK K O   1 
ATOM   3470 C CB  . UNK C 2 56  ? -34.886 1.383   -46.688 1.00 47.40  ? 58  UNK K CB  1 
ATOM   3471 N N   . UNK C 2 57  ? -34.409 0.900   -50.190 1.00 45.26  ? 59  UNK K N   1 
ATOM   3472 C CA  . UNK C 2 57  ? -34.111 0.010   -51.314 1.00 48.01  ? 59  UNK K CA  1 
ATOM   3473 C C   . UNK C 2 57  ? -34.754 -1.371  -51.218 1.00 46.59  ? 59  UNK K C   1 
ATOM   3474 O O   . UNK C 2 57  ? -35.509 -1.682  -50.294 1.00 45.04  ? 59  UNK K O   1 
ATOM   3475 C CB  . UNK C 2 57  ? -32.595 -0.152  -51.471 1.00 61.24  ? 59  UNK K CB  1 
ATOM   3476 N N   . UNK C 2 58  ? -34.440 -2.198  -52.210 1.00 38.60  ? 60  UNK K N   1 
ATOM   3477 C CA  . UNK C 2 58  ? -34.996 -3.540  -52.318 1.00 39.12  ? 60  UNK K CA  1 
ATOM   3478 C C   . UNK C 2 58  ? -33.877 -4.564  -52.464 1.00 40.81  ? 60  UNK K C   1 
ATOM   3479 O O   . UNK C 2 58  ? -32.759 -4.224  -52.852 1.00 41.55  ? 60  UNK K O   1 
ATOM   3480 C CB  . UNK C 2 58  ? -35.959 -3.632  -53.504 1.00 36.41  ? 60  UNK K CB  1 
ATOM   3481 N N   . UNK C 2 59  ? -34.187 -5.815  -52.143 1.00 38.81  ? 61  UNK K N   1 
ATOM   3482 C CA  . UNK C 2 59  ? -33.213 -6.898  -52.218 1.00 38.63  ? 61  UNK K CA  1 
ATOM   3483 C C   . UNK C 2 59  ? -33.867 -8.139  -52.820 1.00 30.50  ? 61  UNK K C   1 
ATOM   3484 O O   . UNK C 2 59  ? -35.081 -8.302  -52.726 1.00 34.29  ? 61  UNK K O   1 
ATOM   3485 C CB  . UNK C 2 59  ? -32.641 -7.205  -50.836 1.00 32.54  ? 61  UNK K CB  1 
ATOM   3486 N N   . UNK C 2 60  ? -33.068 -9.005  -53.436 1.00 31.12  ? 62  UNK K N   1 
ATOM   3487 C CA  . UNK C 2 60  ? -33.618 -10.128 -54.185 1.00 30.86  ? 62  UNK K CA  1 
ATOM   3488 C C   . UNK C 2 60  ? -32.831 -11.420 -53.986 1.00 31.58  ? 62  UNK K C   1 
ATOM   3489 O O   . UNK C 2 60  ? -31.646 -11.403 -53.648 1.00 34.03  ? 62  UNK K O   1 
ATOM   3490 C CB  . UNK C 2 60  ? -33.676 -9.790  -55.677 1.00 36.93  ? 62  UNK K CB  1 
ATOM   3491 N N   . UNK C 2 61  ? -33.511 -12.543 -54.196 1.00 31.07  ? 63  UNK K N   1 
ATOM   3492 C CA  . UNK C 2 61  ? -32.870 -13.851 -54.184 1.00 33.17  ? 63  UNK K CA  1 
ATOM   3493 C C   . UNK C 2 61  ? -32.096 -14.049 -55.481 1.00 39.99  ? 63  UNK K C   1 
ATOM   3494 O O   . UNK C 2 61  ? -32.355 -13.364 -56.472 1.00 42.47  ? 63  UNK K O   1 
ATOM   3495 C CB  . UNK C 2 61  ? -33.905 -14.962 -54.000 1.00 32.85  ? 63  UNK K CB  1 
ATOM   3496 N N   . ASP C 2 62  ? -31.155 -14.987 -55.477 1.00 37.17  ? 64  ASP K N   1 
ATOM   3497 C CA  . ASP C 2 62  ? -30.280 -15.199 -56.627 1.00 47.85  ? 64  ASP K CA  1 
ATOM   3498 C C   . ASP C 2 62  ? -31.027 -15.758 -57.836 1.00 45.87  ? 64  ASP K C   1 
ATOM   3499 O O   . ASP C 2 62  ? -30.652 -15.503 -58.981 1.00 45.65  ? 64  ASP K O   1 
ATOM   3500 C CB  . ASP C 2 62  ? -29.126 -16.133 -56.249 1.00 46.46  ? 64  ASP K CB  1 
ATOM   3501 C CG  . ASP C 2 62  ? -29.600 -17.444 -55.638 1.00 56.45  ? 64  ASP K CG  1 
ATOM   3502 O OD1 . ASP C 2 62  ? -30.813 -17.734 -55.682 1.00 66.40  ? 64  ASP K OD1 1 
ATOM   3503 O OD2 . ASP C 2 62  ? -28.748 -18.186 -55.106 1.00 65.64  ? 64  ASP K OD2 1 
ATOM   3504 N N   . SER C 2 63  ? -32.086 -16.518 -57.574 1.00 45.43  ? 65  SER K N   1 
ATOM   3505 C CA  . SER C 2 63  ? -32.825 -17.198 -58.633 1.00 50.36  ? 65  SER K CA  1 
ATOM   3506 C C   . SER C 2 63  ? -33.734 -16.262 -59.425 1.00 49.27  ? 65  SER K C   1 
ATOM   3507 O O   . SER C 2 63  ? -34.253 -16.639 -60.476 1.00 56.01  ? 65  SER K O   1 
ATOM   3508 C CB  . SER C 2 63  ? -33.658 -18.340 -58.043 1.00 49.93  ? 65  SER K CB  1 
ATOM   3509 O OG  . SER C 2 63  ? -34.574 -17.858 -57.075 1.00 48.43  ? 65  SER K OG  1 
ATOM   3510 N N   . UNK C 2 64  ? -33.924 -15.045 -58.926 1.00 45.04  ? 66  UNK K N   1 
ATOM   3511 C CA  . UNK C 2 64  ? -34.841 -14.105 -59.567 1.00 41.29  ? 66  UNK K CA  1 
ATOM   3512 C C   . UNK C 2 64  ? -34.191 -12.752 -59.836 1.00 42.96  ? 66  UNK K C   1 
ATOM   3513 O O   . UNK C 2 64  ? -34.850 -11.840 -60.338 1.00 45.16  ? 66  UNK K O   1 
ATOM   3514 C CB  . UNK C 2 64  ? -36.091 -13.916 -58.707 1.00 42.37  ? 66  UNK K CB  1 
ATOM   3515 N N   . UNK C 2 65  ? -32.911 -12.625 -59.498 1.00 44.35  ? 67  UNK K N   1 
ATOM   3516 C CA  . UNK C 2 65  ? -32.194 -11.369 -59.689 1.00 40.80  ? 67  UNK K CA  1 
ATOM   3517 C C   . UNK C 2 65  ? -32.172 -11.010 -61.169 1.00 45.73  ? 67  UNK K C   1 
ATOM   3518 O O   . UNK C 2 65  ? -31.994 -11.882 -62.018 1.00 47.09  ? 67  UNK K O   1 
ATOM   3519 C CB  . UNK C 2 65  ? -30.769 -11.466 -59.141 1.00 37.98  ? 67  UNK K CB  1 
ATOM   3520 N N   . GLY C 2 66  ? -32.376 -9.732  -61.473 1.00 48.76  ? 68  GLY K N   1 
ATOM   3521 C CA  . GLY C 2 66  ? -32.358 -9.258  -62.845 1.00 45.22  ? 68  GLY K CA  1 
ATOM   3522 C C   . GLY C 2 66  ? -33.655 -9.491  -63.600 1.00 52.50  ? 68  GLY K C   1 
ATOM   3523 O O   . GLY C 2 66  ? -33.935 -8.810  -64.586 1.00 47.78  ? 68  GLY K O   1 
ATOM   3524 N N   . ARG C 2 67  ? -34.444 -10.464 -63.146 1.00 50.36  ? 69  ARG K N   1 
ATOM   3525 C CA  . ARG C 2 67  ? -35.722 -10.774 -63.774 1.00 47.87  ? 69  ARG K CA  1 
ATOM   3526 C C   . ARG C 2 67  ? -36.924 -10.230 -63.013 1.00 51.79  ? 69  ARG K C   1 
ATOM   3527 O O   . ARG C 2 67  ? -37.926 -9.873  -63.641 1.00 50.00  ? 69  ARG K O   1 
ATOM   3528 C CB  . ARG C 2 67  ? -35.875 -12.291 -63.946 1.00 48.59  ? 69  ARG K CB  1 
ATOM   3529 C CG  . ARG C 2 67  ? -34.780 -12.919 -64.800 1.00 47.41  ? 69  ARG K CG  1 
ATOM   3530 C CD  . ARG C 2 67  ? -35.115 -14.340 -65.241 1.00 42.37  ? 69  ARG K CD  1 
ATOM   3531 N NE  . ARG C 2 67  ? -35.249 -15.267 -64.123 1.00 47.28  ? 69  ARG K NE  1 
ATOM   3532 C CZ  . ARG C 2 67  ? -36.400 -15.767 -63.696 1.00 49.29  ? 69  ARG K CZ  1 
ATOM   3533 N NH1 . ARG C 2 67  ? -37.549 -15.448 -64.270 1.00 47.74  ? 69  ARG K NH1 1 
ATOM   3534 N NH2 . ARG C 2 67  ? -36.398 -16.613 -62.669 1.00 45.18  ? 69  ARG K NH2 1 
ATOM   3535 N N   . PHE C 2 68  ? -36.856 -10.153 -61.686 1.00 50.44  ? 70  PHE K N   1 
ATOM   3536 C CA  . PHE C 2 68  ? -37.965 -9.674  -60.872 1.00 43.25  ? 70  PHE K CA  1 
ATOM   3537 C C   . PHE C 2 68  ? -37.660 -8.297  -60.293 1.00 44.11  ? 70  PHE K C   1 
ATOM   3538 O O   . PHE C 2 68  ? -36.499 -7.924  -60.101 1.00 47.67  ? 70  PHE K O   1 
ATOM   3539 C CB  . PHE C 2 68  ? -38.283 -10.646 -59.727 1.00 49.11  ? 70  PHE K CB  1 
ATOM   3540 C CG  . PHE C 2 68  ? -38.918 -11.943 -60.171 1.00 46.20  ? 70  PHE K CG  1 
ATOM   3541 C CD1 . PHE C 2 68  ? -38.987 -12.290 -61.511 1.00 48.03  ? 70  PHE K CD1 1 
ATOM   3542 C CD2 . PHE C 2 68  ? -39.461 -12.810 -59.236 1.00 41.42  ? 70  PHE K CD2 1 
ATOM   3543 C CE1 . PHE C 2 68  ? -39.567 -13.480 -61.908 1.00 50.17  ? 70  PHE K CE1 1 
ATOM   3544 C CE2 . PHE C 2 68  ? -40.048 -13.999 -59.628 1.00 44.98  ? 70  PHE K CE2 1 
ATOM   3545 C CZ  . PHE C 2 68  ? -40.101 -14.333 -60.966 1.00 47.29  ? 70  PHE K CZ  1 
ATOM   3546 N N   . THR C 2 69  ? -38.724 -7.547  -60.018 1.00 42.93  ? 71  THR K N   1 
ATOM   3547 C CA  . THR C 2 69  ? -38.616 -6.215  -59.423 1.00 45.41  ? 71  THR K CA  1 
ATOM   3548 C C   . THR C 2 69  ? -39.714 -5.977  -58.385 1.00 46.79  ? 71  THR K C   1 
ATOM   3549 O O   . THR C 2 69  ? -40.895 -6.140  -58.674 1.00 49.31  ? 71  THR K O   1 
ATOM   3550 C CB  . THR C 2 69  ? -38.693 -5.111  -60.495 1.00 46.18  ? 71  THR K CB  1 
ATOM   3551 O OG1 . THR C 2 69  ? -37.583 -5.233  -61.393 1.00 59.47  ? 71  THR K OG1 1 
ATOM   3552 C CG2 . THR C 2 69  ? -38.669 -3.733  -59.848 1.00 46.18  ? 71  THR K CG2 1 
ATOM   3553 N N   . UNK C 2 70  ? -39.325 -5.585  -57.176 1.00 47.60  ? 72  UNK K N   1 
ATOM   3554 C CA  . UNK C 2 70  ? -40.300 -5.290  -56.129 1.00 51.12  ? 72  UNK K CA  1 
ATOM   3555 C C   . UNK C 2 70  ? -40.483 -3.783  -55.960 1.00 48.97  ? 72  UNK K C   1 
ATOM   3556 O O   . UNK C 2 70  ? -39.520 -3.022  -56.063 1.00 44.16  ? 72  UNK K O   1 
ATOM   3557 C CB  . UNK C 2 70  ? -39.874 -5.921  -54.803 1.00 42.06  ? 72  UNK K CB  1 
ATOM   3558 N N   . SER C 2 71  ? -41.717 -3.358  -55.705 1.00 49.99  ? 73  SER K N   1 
ATOM   3559 C CA  . SER C 2 71  ? -42.003 -1.939  -55.501 1.00 53.16  ? 73  SER K CA  1 
ATOM   3560 C C   . SER C 2 71  ? -43.159 -1.730  -54.525 1.00 48.80  ? 73  SER K C   1 
ATOM   3561 O O   . SER C 2 71  ? -43.896 -2.664  -54.213 1.00 47.53  ? 73  SER K O   1 
ATOM   3562 C CB  . SER C 2 71  ? -42.313 -1.257  -56.834 1.00 51.09  ? 73  SER K CB  1 
ATOM   3563 O OG  . SER C 2 71  ? -43.346 -1.936  -57.526 1.00 54.72  ? 73  SER K OG  1 
ATOM   3564 N N   . UNK C 2 72  ? -43.321 -0.496  -54.055 1.00 50.29  ? 74  UNK K N   1 
ATOM   3565 C CA  . UNK C 2 72  ? -44.335 -0.196  -53.050 1.00 55.66  ? 74  UNK K CA  1 
ATOM   3566 C C   . UNK C 2 72  ? -45.138 1.064   -53.362 1.00 53.61  ? 74  UNK K C   1 
ATOM   3567 O O   . UNK C 2 72  ? -44.624 2.021   -53.944 1.00 51.46  ? 74  UNK K O   1 
ATOM   3568 C CB  . UNK C 2 72  ? -43.681 -0.055  -51.674 1.00 47.47  ? 74  UNK K CB  1 
ATOM   3569 N N   . ASP C 2 73  ? -46.408 1.050   -52.969 1.00 56.43  ? 75  ASP K N   1 
ATOM   3570 C CA  . ASP C 2 73  ? -47.268 2.220   -53.049 1.00 56.16  ? 75  ASP K CA  1 
ATOM   3571 C C   . ASP C 2 73  ? -47.852 2.444   -51.657 1.00 51.70  ? 75  ASP K C   1 
ATOM   3572 O O   . ASP C 2 73  ? -48.854 1.828   -51.287 1.00 55.47  ? 75  ASP K O   1 
ATOM   3573 C CB  . ASP C 2 73  ? -48.374 2.024   -54.092 1.00 52.88  ? 75  ASP K CB  1 
ATOM   3574 C CG  . ASP C 2 73  ? -49.133 3.308   -54.399 1.00 57.89  ? 75  ASP K CG  1 
ATOM   3575 O OD1 . ASP C 2 73  ? -49.138 4.231   -53.558 1.00 56.61  ? 75  ASP K OD1 1 
ATOM   3576 O OD2 . ASP C 2 73  ? -49.734 3.390   -55.491 1.00 55.00  ? 75  ASP K OD2 1 
ATOM   3577 N N   . UNK C 2 74  ? -47.204 3.314   -50.888 1.00 50.47  ? 76  UNK K N   1 
ATOM   3578 C CA  . UNK C 2 74  ? -47.582 3.555   -49.499 1.00 59.91  ? 76  UNK K CA  1 
ATOM   3579 C C   . UNK C 2 74  ? -48.942 4.235   -49.405 1.00 63.26  ? 76  UNK K C   1 
ATOM   3580 O O   . UNK C 2 74  ? -49.643 4.107   -48.399 1.00 61.42  ? 76  UNK K O   1 
ATOM   3581 C CB  . UNK C 2 74  ? -46.521 4.405   -48.796 1.00 55.26  ? 76  UNK K CB  1 
ATOM   3582 N N   . UNK C 2 75  ? -49.309 4.958   -50.457 1.00 59.95  ? 77  UNK K N   1 
ATOM   3583 C CA  . UNK C 2 75  ? -50.595 5.640   -50.503 1.00 60.27  ? 77  UNK K CA  1 
ATOM   3584 C C   . UNK C 2 75  ? -51.728 4.624   -50.583 1.00 60.70  ? 77  UNK K C   1 
ATOM   3585 O O   . UNK C 2 75  ? -52.676 4.672   -49.798 1.00 65.76  ? 77  UNK K O   1 
ATOM   3586 C CB  . UNK C 2 75  ? -50.657 6.600   -51.693 1.00 60.56  ? 77  UNK K CB  1 
ATOM   3587 N N   . UNK C 2 76  ? -51.617 3.697   -51.530 1.00 59.76  ? 78  UNK K N   1 
ATOM   3588 C CA  . UNK C 2 76  ? -52.622 2.656   -51.710 1.00 55.95  ? 78  UNK K CA  1 
ATOM   3589 C C   . UNK C 2 76  ? -52.367 1.476   -50.776 1.00 59.45  ? 78  UNK K C   1 
ATOM   3590 O O   . UNK C 2 76  ? -53.056 0.456   -50.863 1.00 64.56  ? 78  UNK K O   1 
ATOM   3591 C CB  . UNK C 2 76  ? -52.646 2.180   -53.165 1.00 50.66  ? 78  UNK K CB  1 
ATOM   3592 N N   . UNK C 2 77  ? -51.380 1.630   -49.893 1.00 57.28  ? 79  UNK K N   1 
ATOM   3593 C CA  . UNK C 2 77  ? -50.992 0.590   -48.941 1.00 60.04  ? 79  UNK K CA  1 
ATOM   3594 C C   . UNK C 2 77  ? -50.810 -0.759  -49.623 1.00 59.95  ? 79  UNK K C   1 
ATOM   3595 O O   . UNK C 2 77  ? -51.338 -1.773  -49.161 1.00 57.26  ? 79  UNK K O   1 
ATOM   3596 C CB  . UNK C 2 77  ? -52.033 0.476   -47.826 1.00 55.87  ? 79  UNK K CB  1 
ATOM   3597 N N   . UNK C 2 78  ? -50.066 -0.769  -50.724 1.00 55.49  ? 80  UNK K N   1 
ATOM   3598 C CA  . UNK C 2 78  ? -49.913 -1.990  -51.506 1.00 57.55  ? 80  UNK K CA  1 
ATOM   3599 C C   . UNK C 2 78  ? -48.468 -2.261  -51.911 1.00 56.29  ? 80  UNK K C   1 
ATOM   3600 O O   . UNK C 2 78  ? -47.623 -1.365  -51.938 1.00 49.05  ? 80  UNK K O   1 
ATOM   3601 C CB  . UNK C 2 78  ? -50.793 -1.923  -52.756 1.00 49.66  ? 80  UNK K CB  1 
ATOM   3602 N N   . UNK C 2 79  ? -48.194 -3.522  -52.222 1.00 56.13  ? 81  UNK K N   1 
ATOM   3603 C CA  . UNK C 2 79  ? -46.880 -3.918  -52.714 1.00 53.25  ? 81  UNK K CA  1 
ATOM   3604 C C   . UNK C 2 79  ? -47.033 -4.594  -54.071 1.00 47.41  ? 81  UNK K C   1 
ATOM   3605 O O   . UNK C 2 79  ? -48.090 -5.149  -54.367 1.00 52.81  ? 81  UNK K O   1 
ATOM   3606 C CB  . UNK C 2 79  ? -46.186 -4.848  -51.719 1.00 43.03  ? 81  UNK K CB  1 
ATOM   3607 N N   . UNK C 2 80  ? -45.987 -4.550  -54.891 1.00 43.08  ? 82  UNK K N   1 
ATOM   3608 C CA  . UNK C 2 80  ? -46.062 -5.114  -56.233 1.00 49.43  ? 82  UNK K CA  1 
ATOM   3609 C C   . UNK C 2 80  ? -44.795 -5.873  -56.613 1.00 47.97  ? 82  UNK K C   1 
ATOM   3610 O O   . UNK C 2 80  ? -43.675 -5.418  -56.365 1.00 47.10  ? 82  UNK K O   1 
ATOM   3611 C CB  . UNK C 2 80  ? -46.330 -4.010  -57.258 1.00 49.11  ? 82  UNK K CB  1 
ATOM   3612 N N   . LEU C 2 81  ? -44.991 -7.038  -57.220 1.00 43.23  ? 83  LEU K N   1 
ATOM   3613 C CA  . LEU C 2 81  ? -43.896 -7.844  -57.741 1.00 46.62  ? 83  LEU K CA  1 
ATOM   3614 C C   . LEU C 2 81  ? -44.028 -8.011  -59.254 1.00 51.06  ? 83  LEU K C   1 
ATOM   3615 O O   . LEU C 2 81  ? -44.936 -8.689  -59.740 1.00 51.99  ? 83  LEU K O   1 
ATOM   3616 C CB  . LEU C 2 81  ? -43.860 -9.215  -57.063 1.00 44.19  ? 83  LEU K CB  1 
ATOM   3617 C CG  . LEU C 2 81  ? -42.729 -10.148 -57.497 1.00 43.99  ? 83  LEU K CG  1 
ATOM   3618 C CD1 . LEU C 2 81  ? -41.392 -9.652  -56.962 1.00 38.10  ? 83  LEU K CD1 1 
ATOM   3619 C CD2 . LEU C 2 81  ? -42.997 -11.579 -57.054 1.00 40.67  ? 83  LEU K CD2 1 
ATOM   3620 N N   . GLN C 2 82  ? -43.129 -7.366  -59.990 1.00 54.64  ? 84  GLN K N   1 
ATOM   3621 C CA  . GLN C 2 82  ? -43.070 -7.490  -61.436 1.00 49.24  ? 84  GLN K CA  1 
ATOM   3622 C C   . GLN C 2 82  ? -42.158 -8.650  -61.803 1.00 46.63  ? 84  GLN K C   1 
ATOM   3623 O O   . GLN C 2 82  ? -41.010 -8.703  -61.366 1.00 50.09  ? 84  GLN K O   1 
ATOM   3624 C CB  . GLN C 2 82  ? -42.564 -6.193  -62.069 1.00 49.93  ? 84  GLN K CB  1 
ATOM   3625 C CG  . GLN C 2 82  ? -42.488 -6.229  -63.584 1.00 51.54  ? 84  GLN K CG  1 
ATOM   3626 C CD  . GLN C 2 82  ? -43.855 -6.234  -64.232 1.00 49.63  ? 84  GLN K CD  1 
ATOM   3627 O OE1 . GLN C 2 82  ? -44.751 -5.497  -63.822 1.00 51.25  ? 84  GLN K OE1 1 
ATOM   3628 N NE2 . GLN C 2 82  ? -44.023 -7.069  -65.251 1.00 51.43  ? 84  GLN K NE2 1 
ATOM   3629 N N   . UNK C 2 83  ? -42.671 -9.576  -62.603 1.00 48.28  ? 85  UNK K N   1 
ATOM   3630 C CA  . UNK C 2 83  ? -41.923 -10.760 -62.994 1.00 50.41  ? 85  UNK K CA  1 
ATOM   3631 C C   . UNK C 2 83  ? -41.747 -10.817 -64.509 1.00 53.47  ? 85  UNK K C   1 
ATOM   3632 O O   . UNK C 2 83  ? -42.712 -11.025 -65.248 1.00 45.65  ? 85  UNK K O   1 
ATOM   3633 C CB  . UNK C 2 83  ? -42.629 -12.021 -62.495 1.00 47.56  ? 85  UNK K CB  1 
ATOM   3634 N N   . UNK C 2 84  ? -40.512 -10.628 -64.962 1.00 53.91  ? 86  UNK K N   1 
ATOM   3635 C CA  . UNK C 2 84  ? -40.200 -10.658 -66.387 1.00 48.26  ? 86  UNK K CA  1 
ATOM   3636 C C   . UNK C 2 84  ? -39.341 -11.873 -66.721 1.00 52.79  ? 86  UNK K C   1 
ATOM   3637 O O   . UNK C 2 84  ? -38.685 -12.431 -65.838 1.00 49.55  ? 86  UNK K O   1 
ATOM   3638 C CB  . UNK C 2 84  ? -39.484 -9.373  -66.812 1.00 45.33  ? 86  UNK K CB  1 
ATOM   3639 N N   . UNK C 2 85  ? -39.352 -12.266 -67.993 1.00 49.71  ? 87  UNK K N   1 
ATOM   3640 C CA  . UNK C 2 85  ? -38.613 -13.433 -68.471 1.00 48.05  ? 87  UNK K CA  1 
ATOM   3641 C C   . UNK C 2 85  ? -38.959 -14.674 -67.653 1.00 51.83  ? 87  UNK K C   1 
ATOM   3642 O O   . UNK C 2 85  ? -38.076 -15.433 -67.251 1.00 49.55  ? 87  UNK K O   1 
ATOM   3643 C CB  . UNK C 2 85  ? -37.110 -13.168 -68.436 1.00 37.39  ? 87  UNK K CB  1 
ATOM   3644 N N   . LEU C 2 86  ? -40.252 -14.865 -67.409 1.00 53.73  ? 88  LEU K N   1 
ATOM   3645 C CA  . LEU C 2 86  ? -40.745 -15.990 -66.618 1.00 54.77  ? 88  LEU K CA  1 
ATOM   3646 C C   . LEU C 2 86  ? -40.325 -17.335 -67.196 1.00 55.42  ? 88  LEU K C   1 
ATOM   3647 O O   . LEU C 2 86  ? -40.518 -17.600 -68.382 1.00 60.54  ? 88  LEU K O   1 
ATOM   3648 C CB  . LEU C 2 86  ? -42.270 -15.934 -66.513 1.00 57.89  ? 88  LEU K CB  1 
ATOM   3649 C CG  . LEU C 2 86  ? -42.892 -14.797 -65.703 1.00 54.79  ? 88  LEU K CG  1 
ATOM   3650 C CD1 . LEU C 2 86  ? -44.302 -14.517 -66.189 1.00 59.77  ? 88  LEU K CD1 1 
ATOM   3651 C CD2 . LEU C 2 86  ? -42.903 -15.160 -64.230 1.00 57.32  ? 88  LEU K CD2 1 
ATOM   3652 N N   . UNK C 2 87  ? -39.750 -18.182 -66.350 1.00 55.02  ? 89  UNK K N   1 
ATOM   3653 C CA  . UNK C 2 87  ? -39.441 -19.553 -66.732 1.00 52.14  ? 89  UNK K CA  1 
ATOM   3654 C C   . UNK C 2 87  ? -40.393 -20.503 -66.014 1.00 59.33  ? 89  UNK K C   1 
ATOM   3655 O O   . UNK C 2 87  ? -41.054 -20.107 -65.054 1.00 56.24  ? 89  UNK K O   1 
ATOM   3656 C CB  . UNK C 2 87  ? -37.987 -19.895 -66.407 1.00 43.68  ? 89  UNK K CB  1 
ATOM   3657 N N   . UNK C 2 88  ? -40.463 -21.746 -66.481 1.00 57.40  ? 90  UNK K N   1 
ATOM   3658 C CA  . UNK C 2 88  ? -41.350 -22.741 -65.884 1.00 54.39  ? 90  UNK K CA  1 
ATOM   3659 C C   . UNK C 2 88  ? -40.963 -23.031 -64.436 1.00 56.63  ? 90  UNK K C   1 
ATOM   3660 O O   . UNK C 2 88  ? -41.790 -23.472 -63.637 1.00 55.44  ? 90  UNK K O   1 
ATOM   3661 C CB  . UNK C 2 88  ? -41.333 -24.034 -66.700 1.00 53.67  ? 90  UNK K CB  1 
ATOM   3662 N N   . UNK C 2 89  ? -39.702 -22.770 -64.104 1.00 56.01  ? 91  UNK K N   1 
ATOM   3663 C CA  . UNK C 2 89  ? -39.190 -23.003 -62.758 1.00 54.43  ? 91  UNK K CA  1 
ATOM   3664 C C   . UNK C 2 89  ? -39.778 -22.023 -61.743 1.00 55.49  ? 91  UNK K C   1 
ATOM   3665 O O   . UNK C 2 89  ? -39.571 -22.174 -60.538 1.00 54.56  ? 91  UNK K O   1 
ATOM   3666 C CB  . UNK C 2 89  ? -37.663 -22.905 -62.750 1.00 42.00  ? 91  UNK K CB  1 
ATOM   3667 N N   . ASP C 2 90  ? -40.511 -21.027 -62.231 1.00 53.34  ? 92  ASP K N   1 
ATOM   3668 C CA  . ASP C 2 90  ? -41.110 -20.018 -61.364 1.00 52.20  ? 92  ASP K CA  1 
ATOM   3669 C C   . ASP C 2 90  ? -42.543 -20.379 -60.980 1.00 53.18  ? 92  ASP K C   1 
ATOM   3670 O O   . ASP C 2 90  ? -43.240 -19.589 -60.341 1.00 58.20  ? 92  ASP K O   1 
ATOM   3671 C CB  . ASP C 2 90  ? -41.083 -18.648 -62.045 1.00 53.71  ? 92  ASP K CB  1 
ATOM   3672 C CG  . ASP C 2 90  ? -39.674 -18.149 -62.296 1.00 53.62  ? 92  ASP K CG  1 
ATOM   3673 O OD1 . ASP C 2 90  ? -38.792 -18.408 -61.451 1.00 55.19  ? 92  ASP K OD1 1 
ATOM   3674 O OD2 . ASP C 2 90  ? -39.447 -17.502 -63.340 1.00 53.50  ? 92  ASP K OD2 1 
ATOM   3675 N N   . UNK C 2 91  ? -42.977 -21.573 -61.372 1.00 53.14  ? 93  UNK K N   1 
ATOM   3676 C CA  . UNK C 2 91  ? -44.328 -22.039 -61.072 1.00 56.94  ? 93  UNK K CA  1 
ATOM   3677 C C   . UNK C 2 91  ? -44.476 -22.396 -59.596 1.00 60.74  ? 93  UNK K C   1 
ATOM   3678 O O   . UNK C 2 91  ? -43.927 -23.401 -59.139 1.00 61.68  ? 93  UNK K O   1 
ATOM   3679 C CB  . UNK C 2 91  ? -44.682 -23.247 -61.942 1.00 55.97  ? 93  UNK K CB  1 
ATOM   3680 N N   . ALA C 2 92  ? -45.223 -21.576 -58.861 1.00 60.78  ? 94  ALA K N   1 
ATOM   3681 C CA  . ALA C 2 92  ? -45.419 -21.783 -57.430 1.00 59.52  ? 94  ALA K CA  1 
ATOM   3682 C C   . ALA C 2 92  ? -46.557 -20.920 -56.892 1.00 52.63  ? 94  ALA K C   1 
ATOM   3683 O O   . ALA C 2 92  ? -47.131 -20.107 -57.614 1.00 55.36  ? 94  ALA K O   1 
ATOM   3684 C CB  . ALA C 2 92  ? -44.132 -21.482 -56.673 1.00 54.11  ? 94  ALA K CB  1 
ATOM   3685 N N   . UNK C 2 93  ? -46.882 -21.098 -55.616 1.00 59.04  ? 95  UNK K N   1 
ATOM   3686 C CA  . UNK C 2 93  ? -47.786 -20.182 -54.938 1.00 56.98  ? 95  UNK K CA  1 
ATOM   3687 C C   . UNK C 2 93  ? -46.953 -19.065 -54.322 1.00 53.47  ? 95  UNK K C   1 
ATOM   3688 O O   . UNK C 2 93  ? -46.063 -19.329 -53.511 1.00 54.76  ? 95  UNK K O   1 
ATOM   3689 C CB  . UNK C 2 93  ? -48.606 -20.904 -53.868 1.00 56.26  ? 95  UNK K CB  1 
ATOM   3690 N N   . TYR C 2 94  ? -47.222 -17.828 -54.729 1.00 54.58  ? 96  TYR K N   1 
ATOM   3691 C CA  . TYR C 2 94  ? -46.477 -16.677 -54.243 1.00 46.86  ? 96  TYR K CA  1 
ATOM   3692 C C   . TYR C 2 94  ? -47.199 -16.028 -53.071 1.00 48.06  ? 96  TYR K C   1 
ATOM   3693 O O   . TYR C 2 94  ? -48.355 -15.610 -53.187 1.00 47.36  ? 96  TYR K O   1 
ATOM   3694 C CB  . TYR C 2 94  ? -46.257 -15.660 -55.367 1.00 48.51  ? 96  TYR K CB  1 
ATOM   3695 C CG  . TYR C 2 94  ? -45.210 -16.081 -56.376 1.00 48.96  ? 96  TYR K CG  1 
ATOM   3696 C CD1 . TYR C 2 94  ? -45.451 -17.119 -57.266 1.00 50.83  ? 96  TYR K CD1 1 
ATOM   3697 C CD2 . TYR C 2 94  ? -43.980 -15.439 -56.437 1.00 48.91  ? 96  TYR K CD2 1 
ATOM   3698 C CE1 . TYR C 2 94  ? -44.495 -17.508 -58.188 1.00 53.31  ? 96  TYR K CE1 1 
ATOM   3699 C CE2 . TYR C 2 94  ? -43.019 -15.820 -57.355 1.00 47.08  ? 96  TYR K CE2 1 
ATOM   3700 C CZ  . TYR C 2 94  ? -43.282 -16.855 -58.229 1.00 50.82  ? 96  TYR K CZ  1 
ATOM   3701 O OH  . TYR C 2 94  ? -42.329 -17.238 -59.145 1.00 51.09  ? 96  TYR K OH  1 
ATOM   3702 N N   . TYR C 2 95  ? -46.510 -15.966 -51.936 1.00 51.55  ? 97  TYR K N   1 
ATOM   3703 C CA  . TYR C 2 95  ? -47.034 -15.383 -50.713 1.00 44.34  ? 97  TYR K CA  1 
ATOM   3704 C C   . TYR C 2 95  ? -46.353 -14.048 -50.444 1.00 44.60  ? 97  TYR K C   1 
ATOM   3705 O O   . TYR C 2 95  ? -45.192 -13.836 -50.807 1.00 47.77  ? 97  TYR K O   1 
ATOM   3706 C CB  . TYR C 2 95  ? -46.817 -16.316 -49.517 1.00 42.51  ? 97  TYR K CB  1 
ATOM   3707 C CG  . TYR C 2 95  ? -47.432 -17.688 -49.674 1.00 49.38  ? 97  TYR K CG  1 
ATOM   3708 C CD1 . TYR C 2 95  ? -46.743 -18.711 -50.313 1.00 53.00  ? 97  TYR K CD1 1 
ATOM   3709 C CD2 . TYR C 2 95  ? -48.696 -17.964 -49.171 1.00 51.65  ? 97  TYR K CD2 1 
ATOM   3710 C CE1 . TYR C 2 95  ? -47.300 -19.967 -50.456 1.00 52.83  ? 97  TYR K CE1 1 
ATOM   3711 C CE2 . TYR C 2 95  ? -49.261 -19.219 -49.307 1.00 53.96  ? 97  TYR K CE2 1 
ATOM   3712 C CZ  . TYR C 2 95  ? -48.558 -20.216 -49.951 1.00 54.15  ? 97  TYR K CZ  1 
ATOM   3713 O OH  . TYR C 2 95  ? -49.116 -21.467 -50.090 1.00 56.27  ? 97  TYR K OH  1 
ATOM   3714 N N   . CYS C 2 96  ? -47.091 -13.149 -49.806 1.00 47.96  ? 98  CYS K N   1 
ATOM   3715 C CA  . CYS C 2 96  ? -46.524 -11.892 -49.346 1.00 42.34  ? 98  CYS K CA  1 
ATOM   3716 C C   . CYS C 2 96  ? -46.619 -11.831 -47.829 1.00 44.30  ? 98  CYS K C   1 
ATOM   3717 O O   . CYS C 2 96  ? -47.599 -12.287 -47.240 1.00 44.96  ? 98  CYS K O   1 
ATOM   3718 C CB  . CYS C 2 96  ? -47.241 -10.702 -49.982 1.00 40.30  ? 98  CYS K CB  1 
ATOM   3719 S SG  . CYS C 2 96  ? -46.546 -9.094  -49.535 1.00 52.65  ? 98  CYS K SG  1 
ATOM   3720 N N   . UNK C 2 97  ? -45.593 -11.273 -47.199 1.00 42.51  ? 99  UNK K N   1 
ATOM   3721 C CA  . UNK C 2 97  ? -45.544 -11.206 -45.747 1.00 41.43  ? 99  UNK K CA  1 
ATOM   3722 C C   . UNK C 2 97  ? -45.040 -9.849  -45.285 1.00 40.82  ? 99  UNK K C   1 
ATOM   3723 O O   . UNK C 2 97  ? -44.310 -9.155  -46.000 1.00 43.16  ? 99  UNK K O   1 
ATOM   3724 C CB  . UNK C 2 97  ? -44.654 -12.316 -45.187 1.00 37.82  ? 99  UNK K CB  1 
ATOM   3725 N N   . UNK C 2 98  ? -45.440 -9.471  -44.077 1.00 41.37  ? 100 UNK K N   1 
ATOM   3726 C CA  . UNK C 2 98  ? -44.979 -8.217  -43.495 1.00 40.95  ? 100 UNK K CA  1 
ATOM   3727 C C   . UNK C 2 98  ? -43.905 -8.473  -42.446 1.00 43.17  ? 100 UNK K C   1 
ATOM   3728 O O   . UNK C 2 98  ? -44.087 -9.294  -41.548 1.00 49.25  ? 100 UNK K O   1 
ATOM   3729 C CB  . UNK C 2 98  ? -46.146 -7.444  -42.882 1.00 42.07  ? 100 UNK K CB  1 
ATOM   3730 N N   . UNK C 2 99  ? -42.781 -7.775  -42.571 1.00 39.51  ? 101 UNK K N   1 
ATOM   3731 C CA  . UNK C 2 99  ? -41.746 -7.818  -41.548 1.00 38.26  ? 101 UNK K CA  1 
ATOM   3732 C C   . UNK C 2 99  ? -42.128 -6.865  -40.421 1.00 38.75  ? 101 UNK K C   1 
ATOM   3733 O O   . UNK C 2 99  ? -42.113 -5.646  -40.597 1.00 38.04  ? 101 UNK K O   1 
ATOM   3734 C CB  . UNK C 2 99  ? -40.382 -7.450  -42.132 1.00 42.56  ? 101 UNK K CB  1 
ATOM   3735 N N   . UNK C 2 100 ? -42.477 -7.427  -39.268 1.00 39.33  ? 102 UNK K N   1 
ATOM   3736 C CA  . UNK C 2 100 ? -42.965 -6.635  -38.143 1.00 36.86  ? 102 UNK K CA  1 
ATOM   3737 C C   . UNK C 2 100 ? -41.856 -5.822  -37.483 1.00 40.72  ? 102 UNK K C   1 
ATOM   3738 O O   . UNK C 2 100 ? -42.119 -4.784  -36.874 1.00 45.04  ? 102 UNK K O   1 
ATOM   3739 C CB  . UNK C 2 100 ? -43.631 -7.540  -37.105 1.00 35.73  ? 102 UNK K CB  1 
ATOM   3740 N N   . UNK C 2 101 ? -40.620 -6.296  -37.602 1.00 38.54  ? 103 UNK K N   1 
ATOM   3741 C CA  . UNK C 2 101 ? -39.482 -5.594  -37.025 1.00 32.96  ? 103 UNK K CA  1 
ATOM   3742 C C   . UNK C 2 101 ? -39.074 -4.418  -37.905 1.00 43.28  ? 103 UNK K C   1 
ATOM   3743 O O   . UNK C 2 101 ? -38.690 -4.601  -39.061 1.00 42.47  ? 103 UNK K O   1 
ATOM   3744 C CB  . UNK C 2 101 ? -38.301 -6.548  -36.832 1.00 33.46  ? 103 UNK K CB  1 
ATOM   3745 N N   . UNK C 2 102 ? -39.156 -3.211  -37.351 1.00 45.03  ? 104 UNK K N   1 
ATOM   3746 C CA  . UNK C 2 102 ? -38.795 -1.999  -38.083 1.00 37.97  ? 104 UNK K CA  1 
ATOM   3747 C C   . UNK C 2 102 ? -37.306 -1.972  -38.425 1.00 44.88  ? 104 UNK K C   1 
ATOM   3748 O O   . UNK C 2 102 ? -36.880 -1.225  -39.308 1.00 47.80  ? 104 UNK K O   1 
ATOM   3749 C CB  . UNK C 2 102 ? -39.168 -0.756  -37.273 1.00 37.31  ? 104 UNK K CB  1 
ATOM   3750 N N   . UNK C 2 103 ? -36.523 -2.790  -37.726 1.00 42.85  ? 105 UNK K N   1 
ATOM   3751 C CA  . UNK C 2 103 ? -35.086 -2.876  -37.963 1.00 38.63  ? 105 UNK K CA  1 
ATOM   3752 C C   . UNK C 2 103 ? -34.757 -3.958  -38.989 1.00 40.00  ? 105 UNK K C   1 
ATOM   3753 O O   . UNK C 2 103 ? -33.599 -4.361  -39.123 1.00 48.66  ? 105 UNK K O   1 
ATOM   3754 C CB  . UNK C 2 103 ? -34.343 -3.145  -36.653 1.00 39.82  ? 105 UNK K CB  1 
ATOM   3755 N N   . UNK C 2 104 ? -35.787 -4.430  -39.689 1.00 41.86  ? 106 UNK K N   1 
ATOM   3756 C CA  . UNK C 2 104 ? -35.636 -5.333  -40.831 1.00 40.92  ? 106 UNK K CA  1 
ATOM   3757 C C   . UNK C 2 104 ? -34.965 -6.664  -40.490 1.00 42.53  ? 106 UNK K C   1 
ATOM   3758 O O   . UNK C 2 104 ? -34.207 -7.202  -41.295 1.00 42.87  ? 106 UNK K O   1 
ATOM   3759 C CB  . UNK C 2 104 ? -34.865 -4.634  -41.948 1.00 39.29  ? 106 UNK K CB  1 
ATOM   3760 N N   . UNK C 2 105 ? -35.249 -7.197  -39.306 1.00 37.43  ? 107 UNK K N   1 
ATOM   3761 C CA  . UNK C 2 105 ? -34.736 -8.511  -38.926 1.00 40.37  ? 107 UNK K CA  1 
ATOM   3762 C C   . UNK C 2 105 ? -35.658 -9.602  -39.460 1.00 40.12  ? 107 UNK K C   1 
ATOM   3763 O O   . UNK C 2 105 ? -35.336 -10.791 -39.386 1.00 40.26  ? 107 UNK K O   1 
ATOM   3764 C CB  . UNK C 2 105 ? -34.601 -8.622  -37.408 1.00 38.34  ? 107 UNK K CB  1 
ATOM   3765 N N   . UNK C 2 106 ? -36.799 -9.167  -39.993 1.00 44.54  ? 108 UNK K N   1 
ATOM   3766 C CA  . UNK C 2 106 ? -37.844 -10.024 -40.560 1.00 45.28  ? 108 UNK K CA  1 
ATOM   3767 C C   . UNK C 2 106 ? -38.601 -10.848 -39.536 1.00 40.88  ? 108 UNK K C   1 
ATOM   3768 O O   . UNK C 2 106 ? -38.500 -12.077 -39.514 1.00 41.98  ? 108 UNK K O   1 
ATOM   3769 C CB  . UNK C 2 106 ? -37.277 -10.974 -41.607 1.00 43.48  ? 108 UNK K CB  1 
ATOM   3770 N N   . UNK C 2 107 ? -39.365 -10.170 -38.693 1.00 41.93  ? 109 UNK K N   1 
ATOM   3771 C CA  . UNK C 2 107 ? -40.356 -10.850 -37.884 1.00 38.01  ? 109 UNK K CA  1 
ATOM   3772 C C   . UNK C 2 107 ? -41.576 -11.038 -38.776 1.00 35.04  ? 109 UNK K C   1 
ATOM   3773 O O   . UNK C 2 107 ? -42.483 -10.206 -38.785 1.00 40.18  ? 109 UNK K O   1 
ATOM   3774 C CB  . UNK C 2 107 ? -40.699 -10.051 -36.627 1.00 36.76  ? 109 UNK K CB  1 
ATOM   3775 N N   . UNK C 2 108 ? -41.574 -12.115 -39.556 1.00 33.22  ? 110 UNK K N   1 
ATOM   3776 C CA  . UNK C 2 108 ? -42.681 -12.407 -40.459 1.00 36.27  ? 110 UNK K CA  1 
ATOM   3777 C C   . UNK C 2 108 ? -43.849 -13.014 -39.689 1.00 38.97  ? 110 UNK K C   1 
ATOM   3778 O O   . UNK C 2 108 ? -43.965 -14.235 -39.577 1.00 38.49  ? 110 UNK K O   1 
ATOM   3779 C CB  . UNK C 2 108 ? -42.234 -13.349 -41.579 1.00 36.58  ? 110 UNK K CB  1 
ATOM   3780 N N   . UNK C 2 109 ? -44.711 -12.153 -39.160 1.00 37.95  ? 111 UNK K N   1 
ATOM   3781 C CA  . UNK C 2 109 ? -45.834 -12.598 -38.344 1.00 46.02  ? 111 UNK K CA  1 
ATOM   3782 C C   . UNK C 2 109 ? -47.117 -12.666 -39.166 1.00 44.95  ? 111 UNK K C   1 
ATOM   3783 O O   . UNK C 2 109 ? -47.956 -13.541 -38.945 1.00 46.96  ? 111 UNK K O   1 
ATOM   3784 C CB  . UNK C 2 109 ? -46.025 -11.668 -37.142 1.00 42.91  ? 111 UNK K CB  1 
ATOM   3785 N N   . UNK C 2 110 ? -47.263 -11.746 -40.115 1.00 38.36  ? 112 UNK K N   1 
ATOM   3786 C CA  . UNK C 2 110 ? -48.457 -11.696 -40.954 1.00 38.19  ? 112 UNK K CA  1 
ATOM   3787 C C   . UNK C 2 110 ? -48.162 -12.098 -42.397 1.00 47.04  ? 112 UNK K C   1 
ATOM   3788 O O   . UNK C 2 110 ? -47.274 -11.537 -43.054 1.00 46.75  ? 112 UNK K O   1 
ATOM   3789 C CB  . UNK C 2 110 ? -49.075 -10.297 -40.919 1.00 45.23  ? 112 UNK K CB  1 
ATOM   3790 N N   . TRP C 2 111 ? -48.924 -13.079 -42.878 1.00 44.31  ? 113 TRP K N   1 
ATOM   3791 C CA  . TRP C 2 111 ? -48.784 -13.608 -44.231 1.00 46.90  ? 113 TRP K CA  1 
ATOM   3792 C C   . TRP C 2 111 ? -50.090 -13.480 -45.008 1.00 46.42  ? 113 TRP K C   1 
ATOM   3793 O O   . TRP C 2 111 ? -51.167 -13.392 -44.419 1.00 51.90  ? 113 TRP K O   1 
ATOM   3794 C CB  . TRP C 2 111 ? -48.357 -15.077 -44.194 1.00 46.47  ? 113 TRP K CB  1 
ATOM   3795 C CG  . TRP C 2 111 ? -46.965 -15.298 -43.703 1.00 48.38  ? 113 TRP K CG  1 
ATOM   3796 C CD1 . TRP C 2 111 ? -46.547 -15.320 -42.406 1.00 37.85  ? 113 TRP K CD1 1 
ATOM   3797 C CD2 . TRP C 2 111 ? -45.802 -15.543 -44.503 1.00 47.37  ? 113 TRP K CD2 1 
ATOM   3798 N NE1 . TRP C 2 111 ? -45.196 -15.558 -42.347 1.00 40.90  ? 113 TRP K NE1 1 
ATOM   3799 C CE2 . TRP C 2 111 ? -44.714 -15.698 -43.622 1.00 43.66  ? 113 TRP K CE2 1 
ATOM   3800 C CE3 . TRP C 2 111 ? -45.574 -15.641 -45.879 1.00 44.91  ? 113 TRP K CE3 1 
ATOM   3801 C CZ2 . TRP C 2 111 ? -43.419 -15.946 -44.072 1.00 37.05  ? 113 TRP K CZ2 1 
ATOM   3802 C CZ3 . TRP C 2 111 ? -44.288 -15.889 -46.323 1.00 43.77  ? 113 TRP K CZ3 1 
ATOM   3803 C CH2 . TRP C 2 111 ? -43.227 -16.038 -45.423 1.00 42.60  ? 113 TRP K CH2 1 
ATOM   3804 N N   . GLY C 2 112 ? -49.989 -13.481 -46.333 1.00 46.30  ? 114 GLY K N   1 
ATOM   3805 C CA  . GLY C 2 112 ? -51.161 -13.438 -47.187 1.00 45.96  ? 114 GLY K CA  1 
ATOM   3806 C C   . GLY C 2 112 ? -51.676 -14.826 -47.516 1.00 45.74  ? 114 GLY K C   1 
ATOM   3807 O O   . GLY C 2 112 ? -51.201 -15.818 -46.964 1.00 55.88  ? 114 GLY K O   1 
ATOM   3808 N N   . UNK C 2 113 ? -52.650 -14.899 -48.417 1.00 43.89  ? 115 UNK K N   1 
ATOM   3809 C CA  . UNK C 2 113 ? -53.215 -16.181 -48.823 1.00 45.61  ? 115 UNK K CA  1 
ATOM   3810 C C   . UNK C 2 113 ? -52.408 -16.781 -49.970 1.00 49.72  ? 115 UNK K C   1 
ATOM   3811 O O   . UNK C 2 113 ? -52.373 -18.000 -50.148 1.00 48.81  ? 115 UNK K O   1 
ATOM   3812 C CB  . UNK C 2 113 ? -54.680 -16.021 -49.231 1.00 45.23  ? 115 UNK K CB  1 
ATOM   3813 N N   . GLY C 2 114 ? -51.759 -15.917 -50.743 1.00 47.27  ? 116 GLY K N   1 
ATOM   3814 C CA  . GLY C 2 114 ? -50.924 -16.353 -51.848 1.00 51.61  ? 116 GLY K CA  1 
ATOM   3815 C C   . GLY C 2 114 ? -51.677 -16.505 -53.154 1.00 53.03  ? 116 GLY K C   1 
ATOM   3816 O O   . GLY C 2 114 ? -52.886 -16.733 -53.160 1.00 57.06  ? 116 GLY K O   1 
ATOM   3817 N N   . THR C 2 115 ? -50.963 -16.377 -54.268 1.00 54.59  ? 117 THR K N   1 
ATOM   3818 C CA  . THR C 2 115 ? -51.572 -16.579 -55.580 1.00 57.76  ? 117 THR K CA  1 
ATOM   3819 C C   . THR C 2 115 ? -50.756 -17.539 -56.431 1.00 59.24  ? 117 THR K C   1 
ATOM   3820 O O   . THR C 2 115 ? -49.530 -17.510 -56.411 1.00 55.01  ? 117 THR K O   1 
ATOM   3821 C CB  . THR C 2 115 ? -51.740 -15.254 -56.339 1.00 61.01  ? 117 THR K CB  1 
ATOM   3822 O OG1 . THR C 2 115 ? -50.572 -14.443 -56.159 1.00 57.15  ? 117 THR K OG1 1 
ATOM   3823 C CG2 . THR C 2 115 ? -52.959 -14.514 -55.833 1.00 61.17  ? 117 THR K CG2 1 
ATOM   3824 N N   . UNK C 2 116 ? -51.446 -18.394 -57.177 1.00 64.60  ? 118 UNK K N   1 
ATOM   3825 C CA  . UNK C 2 116 ? -50.777 -19.416 -57.970 1.00 59.10  ? 118 UNK K CA  1 
ATOM   3826 C C   . UNK C 2 116 ? -50.282 -18.861 -59.300 1.00 64.04  ? 118 UNK K C   1 
ATOM   3827 O O   . UNK C 2 116 ? -51.060 -18.329 -60.094 1.00 65.93  ? 118 UNK K O   1 
ATOM   3828 C CB  . UNK C 2 116 ? -51.714 -20.601 -58.214 1.00 58.37  ? 118 UNK K CB  1 
ATOM   3829 N N   . VAL C 2 117 ? -48.978 -18.983 -59.532 1.00 64.69  ? 119 VAL K N   1 
ATOM   3830 C CA  . VAL C 2 117 ? -48.373 -18.615 -60.800 1.00 66.08  ? 119 VAL K CA  1 
ATOM   3831 C C   . VAL C 2 117 ? -47.829 -19.863 -61.475 1.00 67.06  ? 119 VAL K C   1 
ATOM   3832 O O   . VAL C 2 117 ? -46.927 -20.518 -60.954 1.00 63.00  ? 119 VAL K O   1 
ATOM   3833 C CB  . VAL C 2 117 ? -47.261 -17.571 -60.610 1.00 64.31  ? 119 VAL K CB  1 
ATOM   3834 C CG1 . VAL C 2 117 ? -46.667 -17.191 -61.952 1.00 61.17  ? 119 VAL K CG1 1 
ATOM   3835 C CG2 . VAL C 2 117 ? -47.809 -16.340 -59.905 1.00 59.86  ? 119 VAL K CG2 1 
ATOM   3836 N N   . THR C 2 118 ? -48.382 -20.187 -62.639 1.00 68.78  ? 120 THR K N   1 
ATOM   3837 C CA  . THR C 2 118 ? -47.964 -21.345 -63.415 1.00 68.11  ? 120 THR K CA  1 
ATOM   3838 C C   . THR C 2 118 ? -47.458 -20.869 -64.768 1.00 69.05  ? 120 THR K C   1 
ATOM   3839 O O   . THR C 2 118 ? -48.141 -20.106 -65.460 1.00 73.78  ? 120 THR K O   1 
ATOM   3840 C CB  . THR C 2 118 ? -49.111 -22.350 -63.583 1.00 66.95  ? 120 THR K CB  1 
ATOM   3841 O OG1 . THR C 2 118 ? -48.782 -23.289 -64.615 1.00 69.72  ? 120 THR K OG1 1 
ATOM   3842 C CG2 . THR C 2 118 ? -50.411 -21.640 -63.930 1.00 68.06  ? 120 THR K CG2 1 
ATOM   3843 N N   . VAL C 2 119 ? -46.258 -21.309 -65.135 1.00 70.02  ? 121 VAL K N   1 
ATOM   3844 C CA  . VAL C 2 119 ? -45.598 -20.883 -66.362 1.00 67.02  ? 121 VAL K CA  1 
ATOM   3845 C C   . VAL C 2 119 ? -45.457 -22.104 -67.258 1.00 69.78  ? 121 VAL K C   1 
ATOM   3846 O O   . VAL C 2 119 ? -44.656 -23.003 -66.973 1.00 70.59  ? 121 VAL K O   1 
ATOM   3847 C CB  . VAL C 2 119 ? -44.233 -20.240 -66.085 1.00 63.83  ? 121 VAL K CB  1 
ATOM   3848 C CG1 . VAL C 2 119 ? -43.515 -19.941 -67.389 1.00 62.20  ? 121 VAL K CG1 1 
ATOM   3849 C CG2 . VAL C 2 119 ? -44.398 -18.978 -65.253 1.00 62.06  ? 121 VAL K CG2 1 
ATOM   3850 N N   . SER C 2 120 ? -46.234 -22.142 -68.335 1.00 71.42  ? 122 SER K N   1 
ATOM   3851 C CA  . SER C 2 120 ? -46.175 -23.247 -69.283 1.00 74.36  ? 122 SER K CA  1 
ATOM   3852 C C   . SER C 2 120 ? -46.640 -22.803 -70.666 1.00 74.56  ? 122 SER K C   1 
ATOM   3853 O O   . SER C 2 120 ? -47.198 -23.593 -71.427 1.00 81.21  ? 122 SER K O   1 
ATOM   3854 C CB  . SER C 2 120 ? -47.023 -24.421 -68.792 1.00 74.32  ? 122 SER K CB  1 
ATOM   3855 O OG  . SER C 2 120 ? -46.875 -25.547 -69.640 1.00 80.29  ? 122 SER K OG  1 
ATOM   3856 N N   . ASP D 3 1   ? 17.309  -25.598 6.301   1.00 76.90  ? 1   ASP L N   1 
ATOM   3857 C CA  . ASP D 3 1   ? 15.961  -26.122 6.118   1.00 80.01  ? 1   ASP L CA  1 
ATOM   3858 C C   . ASP D 3 1   ? 15.029  -25.576 7.197   1.00 73.67  ? 1   ASP L C   1 
ATOM   3859 O O   . ASP D 3 1   ? 13.819  -25.474 6.992   1.00 77.23  ? 1   ASP L O   1 
ATOM   3860 C CB  . ASP D 3 1   ? 15.977  -27.654 6.137   1.00 85.09  ? 1   ASP L CB  1 
ATOM   3861 C CG  . ASP D 3 1   ? 14.682  -28.262 5.625   1.00 87.14  ? 1   ASP L CG  1 
ATOM   3862 O OD1 . ASP D 3 1   ? 13.644  -28.135 6.307   1.00 85.41  ? 1   ASP L OD1 1 
ATOM   3863 O OD2 . ASP D 3 1   ? 14.702  -28.866 4.532   1.00 81.17  ? 1   ASP L OD2 1 
ATOM   3864 N N   . ILE D 3 2   ? 15.600  -25.218 8.343   1.00 66.32  ? 2   ILE L N   1 
ATOM   3865 C CA  . ILE D 3 2   ? 14.835  -24.659 9.452   1.00 64.42  ? 2   ILE L CA  1 
ATOM   3866 C C   . ILE D 3 2   ? 14.804  -23.143 9.309   1.00 60.69  ? 2   ILE L C   1 
ATOM   3867 O O   . ILE D 3 2   ? 15.853  -22.489 9.292   1.00 60.76  ? 2   ILE L O   1 
ATOM   3868 C CB  . ILE D 3 2   ? 15.428  -25.076 10.806  1.00 65.64  ? 2   ILE L CB  1 
ATOM   3869 C CG1 . ILE D 3 2   ? 15.021  -26.513 11.144  1.00 69.27  ? 2   ILE L CG1 1 
ATOM   3870 C CG2 . ILE D 3 2   ? 14.989  -24.115 11.905  1.00 57.70  ? 2   ILE L CG2 1 
ATOM   3871 C CD1 . ILE D 3 2   ? 15.266  -26.897 12.587  1.00 63.54  ? 2   ILE L CD1 1 
ATOM   3872 N N   . VAL D 3 3   ? 13.603  -22.585 9.207   1.00 63.64  ? 3   VAL L N   1 
ATOM   3873 C CA  . VAL D 3 3   ? 13.415  -21.144 9.102   1.00 61.38  ? 3   VAL L CA  1 
ATOM   3874 C C   . VAL D 3 3   ? 13.233  -20.570 10.500  1.00 56.38  ? 3   VAL L C   1 
ATOM   3875 O O   . VAL D 3 3   ? 12.432  -21.081 11.292  1.00 58.00  ? 3   VAL L O   1 
ATOM   3876 C CB  . VAL D 3 3   ? 12.208  -20.812 8.208   1.00 56.02  ? 3   VAL L CB  1 
ATOM   3877 C CG1 . VAL D 3 3   ? 11.819  -19.347 8.356   1.00 52.23  ? 3   VAL L CG1 1 
ATOM   3878 C CG2 . VAL D 3 3   ? 12.519  -21.138 6.756   1.00 58.78  ? 3   VAL L CG2 1 
ATOM   3879 N N   . LEU D 3 4   ? 13.980  -19.513 10.808  1.00 50.73  ? 4   LEU L N   1 
ATOM   3880 C CA  . LEU D 3 4   ? 13.839  -18.795 12.065  1.00 45.00  ? 4   LEU L CA  1 
ATOM   3881 C C   . LEU D 3 4   ? 13.201  -17.439 11.796  1.00 46.37  ? 4   LEU L C   1 
ATOM   3882 O O   . LEU D 3 4   ? 13.699  -16.667 10.970  1.00 45.67  ? 4   LEU L O   1 
ATOM   3883 C CB  . LEU D 3 4   ? 15.194  -18.624 12.756  1.00 45.52  ? 4   LEU L CB  1 
ATOM   3884 C CG  . LEU D 3 4   ? 16.066  -19.878 12.865  1.00 48.66  ? 4   LEU L CG  1 
ATOM   3885 C CD1 . LEU D 3 4   ? 17.507  -19.507 13.187  1.00 46.35  ? 4   LEU L CD1 1 
ATOM   3886 C CD2 . LEU D 3 4   ? 15.510  -20.839 13.906  1.00 45.19  ? 4   LEU L CD2 1 
ATOM   3887 N N   . THR D 3 5   ? 12.108  -17.156 12.498  1.00 48.54  ? 5   THR L N   1 
ATOM   3888 C CA  . THR D 3 5   ? 11.361  -15.913 12.357  1.00 44.53  ? 5   THR L CA  1 
ATOM   3889 C C   . THR D 3 5   ? 11.479  -15.122 13.651  1.00 46.07  ? 5   THR L C   1 
ATOM   3890 O O   . THR D 3 5   ? 11.138  -15.627 14.725  1.00 47.94  ? 5   THR L O   1 
ATOM   3891 C CB  . THR D 3 5   ? 9.892   -16.183 12.031  1.00 46.61  ? 5   THR L CB  1 
ATOM   3892 O OG1 . THR D 3 5   ? 9.798   -17.257 11.085  1.00 54.98  ? 5   THR L OG1 1 
ATOM   3893 C CG2 . THR D 3 5   ? 9.232   -14.938 11.459  1.00 46.11  ? 5   THR L CG2 1 
ATOM   3894 N N   . GLN D 3 6   ? 11.955  -13.888 13.549  1.00 40.97  ? 6   GLN L N   1 
ATOM   3895 C CA  . GLN D 3 6   ? 12.169  -13.047 14.715  1.00 39.20  ? 6   GLN L CA  1 
ATOM   3896 C C   . GLN D 3 6   ? 11.070  -11.999 14.811  1.00 41.77  ? 6   GLN L C   1 
ATOM   3897 O O   . GLN D 3 6   ? 10.674  -11.402 13.805  1.00 42.32  ? 6   GLN L O   1 
ATOM   3898 C CB  . GLN D 3 6   ? 13.541  -12.375 14.646  1.00 37.01  ? 6   GLN L CB  1 
ATOM   3899 C CG  . GLN D 3 6   ? 14.673  -13.354 14.385  1.00 41.03  ? 6   GLN L CG  1 
ATOM   3900 C CD  . GLN D 3 6   ? 16.006  -12.859 14.903  1.00 36.60  ? 6   GLN L CD  1 
ATOM   3901 O OE1 . GLN D 3 6   ? 17.057  -13.175 14.347  1.00 37.25  ? 6   GLN L OE1 1 
ATOM   3902 N NE2 . GLN D 3 6   ? 15.971  -12.079 15.977  1.00 36.80  ? 6   GLN L NE2 1 
ATOM   3903 N N   . THR D 3 7   ? 10.574  -11.784 16.031  1.00 43.03  ? 7   THR L N   1 
ATOM   3904 C CA  . THR D 3 7   ? 9.499   -10.838 16.286  1.00 49.14  ? 7   THR L CA  1 
ATOM   3905 C C   . THR D 3 7   ? 9.817   -9.993  17.514  1.00 47.06  ? 7   THR L C   1 
ATOM   3906 O O   . THR D 3 7   ? 10.289  -10.521 18.535  1.00 51.76  ? 7   THR L O   1 
ATOM   3907 C CB  . THR D 3 7   ? 8.146   -11.541 16.481  1.00 46.77  ? 7   THR L CB  1 
ATOM   3908 O OG1 . THR D 3 7   ? 8.261   -12.540 17.502  1.00 51.69  ? 7   THR L OG1 1 
ATOM   3909 C CG2 . THR D 3 7   ? 7.679   -12.188 15.183  1.00 43.91  ? 7   THR L CG2 1 
ATOM   3910 N N   . PRO D 3 8   ? 9.590   -8.679  17.439  1.00 42.62  ? 8   PRO L N   1 
ATOM   3911 C CA  . PRO D 3 8   ? 9.149   -7.925  16.259  1.00 42.48  ? 8   PRO L CA  1 
ATOM   3912 C C   . PRO D 3 8   ? 10.319  -7.665  15.320  1.00 45.45  ? 8   PRO L C   1 
ATOM   3913 O O   . PRO D 3 8   ? 11.455  -7.985  15.652  1.00 42.71  ? 8   PRO L O   1 
ATOM   3914 C CB  . PRO D 3 8   ? 8.593   -6.634  16.869  1.00 38.88  ? 8   PRO L CB  1 
ATOM   3915 C CG  . PRO D 3 8   ? 9.446   -6.424  18.089  1.00 44.39  ? 8   PRO L CG  1 
ATOM   3916 C CD  . PRO D 3 8   ? 9.730   -7.810  18.621  1.00 48.31  ? 8   PRO L CD  1 
ATOM   3917 N N   . ALA D 3 9   ? 10.082  -7.103  14.134  1.00 43.93  ? 9   ALA L N   1 
ATOM   3918 C CA  . ALA D 3 9   ? 11.199  -6.733  13.272  1.00 39.21  ? 9   ALA L CA  1 
ATOM   3919 C C   . ALA D 3 9   ? 11.977  -5.560  13.856  1.00 41.21  ? 9   ALA L C   1 
ATOM   3920 O O   . ALA D 3 9   ? 13.211  -5.529  13.788  1.00 43.50  ? 9   ALA L O   1 
ATOM   3921 C CB  . ALA D 3 9   ? 10.694  -6.402  11.869  1.00 40.69  ? 9   ALA L CB  1 
ATOM   3922 N N   . ILE D 3 10  ? 11.274  -4.593  14.442  1.00 38.29  ? 10  ILE L N   1 
ATOM   3923 C CA  . ILE D 3 10  ? 11.886  -3.421  15.055  1.00 38.92  ? 10  ILE L CA  1 
ATOM   3924 C C   . ILE D 3 10  ? 11.267  -3.225  16.431  1.00 39.04  ? 10  ILE L C   1 
ATOM   3925 O O   . ILE D 3 10  ? 10.039  -3.213  16.569  1.00 43.21  ? 10  ILE L O   1 
ATOM   3926 C CB  . ILE D 3 10  ? 11.690  -2.160  14.191  1.00 45.01  ? 10  ILE L CB  1 
ATOM   3927 C CG1 . ILE D 3 10  ? 12.349  -2.342  12.822  1.00 37.85  ? 10  ILE L CG1 1 
ATOM   3928 C CG2 . ILE D 3 10  ? 12.253  -0.935  14.897  1.00 43.92  ? 10  ILE L CG2 1 
ATOM   3929 C CD1 . ILE D 3 10  ? 11.883  -1.346  11.785  1.00 43.07  ? 10  ILE L CD1 1 
ATOM   3930 N N   . MET D 3 11  ? 12.114  -3.078  17.447  1.00 37.34  ? 11  MET L N   1 
ATOM   3931 C CA  . MET D 3 11  ? 11.676  -2.856  18.818  1.00 43.10  ? 11  MET L CA  1 
ATOM   3932 C C   . MET D 3 11  ? 12.169  -1.492  19.281  1.00 43.13  ? 11  MET L C   1 
ATOM   3933 O O   . MET D 3 11  ? 13.371  -1.212  19.223  1.00 43.96  ? 11  MET L O   1 
ATOM   3934 C CB  . MET D 3 11  ? 12.195  -3.958  19.747  1.00 40.51  ? 11  MET L CB  1 
ATOM   3935 C CG  . MET D 3 11  ? 11.874  -3.753  21.221  1.00 49.08  ? 11  MET L CG  1 
ATOM   3936 S SD  . MET D 3 11  ? 10.259  -4.420  21.668  1.00 58.04  ? 11  MET L SD  1 
ATOM   3937 C CE  . MET D 3 11  ? 9.714   -3.228  22.889  1.00 55.17  ? 11  MET L CE  1 
ATOM   3938 N N   . SER D 3 12  ? 11.245  -0.650  19.734  1.00 38.83  ? 12  SER L N   1 
ATOM   3939 C CA  . SER D 3 12  ? 11.566  0.673   20.256  1.00 40.88  ? 12  SER L CA  1 
ATOM   3940 C C   . SER D 3 12  ? 11.360  0.662   21.764  1.00 42.07  ? 12  SER L C   1 
ATOM   3941 O O   . SER D 3 12  ? 10.249  0.402   22.239  1.00 42.62  ? 12  SER L O   1 
ATOM   3942 C CB  . SER D 3 12  ? 10.700  1.748   19.599  1.00 40.05  ? 12  SER L CB  1 
ATOM   3943 O OG  . SER D 3 12  ? 10.780  1.674   18.186  1.00 49.74  ? 12  SER L OG  1 
ATOM   3944 N N   . ALA D 3 13  ? 12.426  0.944   22.511  1.00 38.51  ? 13  ALA L N   1 
ATOM   3945 C CA  . ALA D 3 13  ? 12.387  0.858   23.963  1.00 44.48  ? 13  ALA L CA  1 
ATOM   3946 C C   . ALA D 3 13  ? 13.164  2.010   24.581  1.00 41.96  ? 13  ALA L C   1 
ATOM   3947 O O   . ALA D 3 13  ? 14.250  2.362   24.112  1.00 44.43  ? 13  ALA L O   1 
ATOM   3948 C CB  . ALA D 3 13  ? 12.961  -0.475  24.454  1.00 40.88  ? 13  ALA L CB  1 
ATOM   3949 N N   . SER D 3 14  ? 12.596  2.593   25.636  1.00 44.65  ? 14  SER L N   1 
ATOM   3950 C CA  . SER D 3 14  ? 13.281  3.636   26.378  1.00 51.06  ? 14  SER L CA  1 
ATOM   3951 C C   . SER D 3 14  ? 14.265  3.015   27.367  1.00 50.71  ? 14  SER L C   1 
ATOM   3952 O O   . SER D 3 14  ? 14.051  1.898   27.847  1.00 45.16  ? 14  SER L O   1 
ATOM   3953 C CB  . SER D 3 14  ? 12.279  4.506   27.131  1.00 46.22  ? 14  SER L CB  1 
ATOM   3954 O OG  . SER D 3 14  ? 11.193  4.875   26.300  1.00 54.47  ? 14  SER L OG  1 
ATOM   3955 N N   . PRO D 3 15  ? 15.361  3.715   27.677  1.00 52.83  ? 15  PRO L N   1 
ATOM   3956 C CA  . PRO D 3 15  ? 16.303  3.197   28.680  1.00 56.07  ? 15  PRO L CA  1 
ATOM   3957 C C   . PRO D 3 15  ? 15.642  2.987   30.033  1.00 56.81  ? 15  PRO L C   1 
ATOM   3958 O O   . PRO D 3 15  ? 15.278  3.949   30.717  1.00 61.31  ? 15  PRO L O   1 
ATOM   3959 C CB  . PRO D 3 15  ? 17.383  4.283   28.738  1.00 54.75  ? 15  PRO L CB  1 
ATOM   3960 C CG  . PRO D 3 15  ? 17.334  4.919   27.388  1.00 52.94  ? 15  PRO L CG  1 
ATOM   3961 C CD  . PRO D 3 15  ? 15.884  4.911   26.995  1.00 54.95  ? 15  PRO L CD  1 
ATOM   3962 N N   . GLY D 3 16  ? 15.485  1.725   30.424  1.00 52.35  ? 16  GLY L N   1 
ATOM   3963 C CA  . GLY D 3 16  ? 14.832  1.383   31.671  1.00 50.69  ? 16  GLY L CA  1 
ATOM   3964 C C   . GLY D 3 16  ? 13.701  0.392   31.483  1.00 55.83  ? 16  GLY L C   1 
ATOM   3965 O O   . GLY D 3 16  ? 13.245  -0.231  32.447  1.00 56.51  ? 16  GLY L O   1 
ATOM   3966 N N   . GLU D 3 17  ? 13.234  0.244   30.245  1.00 51.89  ? 17  GLU L N   1 
ATOM   3967 C CA  . GLU D 3 17  ? 12.162  -0.692  29.945  1.00 52.14  ? 17  GLU L CA  1 
ATOM   3968 C C   . GLU D 3 17  ? 12.697  -2.120  29.862  1.00 56.75  ? 17  GLU L C   1 
ATOM   3969 O O   . GLU D 3 17  ? 13.877  -2.358  29.592  1.00 56.65  ? 17  GLU L O   1 
ATOM   3970 C CB  . GLU D 3 17  ? 11.462  -0.316  28.638  1.00 52.38  ? 17  GLU L CB  1 
ATOM   3971 C CG  . GLU D 3 17  ? 10.834  1.069   28.642  1.00 56.08  ? 17  GLU L CG  1 
ATOM   3972 C CD  . GLU D 3 17  ? 10.127  1.390   27.340  1.00 56.65  ? 17  GLU L CD  1 
ATOM   3973 O OE1 . GLU D 3 17  ? 9.930   0.464   26.526  1.00 52.17  ? 17  GLU L OE1 1 
ATOM   3974 O OE2 . GLU D 3 17  ? 9.756   2.565   27.134  1.00 64.74  ? 17  GLU L OE2 1 
ATOM   3975 N N   . LYS D 3 18  ? 11.806  -3.077  30.106  1.00 53.51  ? 18  LYS L N   1 
ATOM   3976 C CA  . LYS D 3 18  ? 12.102  -4.489  29.902  1.00 54.55  ? 18  LYS L CA  1 
ATOM   3977 C C   . LYS D 3 18  ? 11.746  -4.882  28.472  1.00 56.39  ? 18  LYS L C   1 
ATOM   3978 O O   . LYS D 3 18  ? 10.665  -4.544  27.980  1.00 57.17  ? 18  LYS L O   1 
ATOM   3979 C CB  . LYS D 3 18  ? 11.345  -5.346  30.917  1.00 59.80  ? 18  LYS L CB  1 
ATOM   3980 C CG  . LYS D 3 18  ? 11.552  -6.843  30.764  1.00 62.12  ? 18  LYS L CG  1 
ATOM   3981 C CD  . LYS D 3 18  ? 10.690  -7.615  31.749  1.00 64.68  ? 18  LYS L CD  1 
ATOM   3982 C CE  . LYS D 3 18  ? 10.917  -9.113  31.631  1.00 67.82  ? 18  LYS L CE  1 
ATOM   3983 N NZ  . LYS D 3 18  ? 10.247  -9.860  32.732  1.00 74.05  ? 18  LYS L NZ  1 
ATOM   3984 N N   . VAL D 3 19  ? 12.658  -5.592  27.807  1.00 51.85  ? 19  VAL L N   1 
ATOM   3985 C CA  . VAL D 3 19  ? 12.554  -5.892  26.383  1.00 51.44  ? 19  VAL L CA  1 
ATOM   3986 C C   . VAL D 3 19  ? 12.577  -7.402  26.190  1.00 48.14  ? 19  VAL L C   1 
ATOM   3987 O O   . VAL D 3 19  ? 13.326  -8.109  26.871  1.00 50.18  ? 19  VAL L O   1 
ATOM   3988 C CB  . VAL D 3 19  ? 13.701  -5.227  25.591  1.00 49.98  ? 19  VAL L CB  1 
ATOM   3989 C CG1 . VAL D 3 19  ? 13.590  -5.535  24.104  1.00 47.87  ? 19  VAL L CG1 1 
ATOM   3990 C CG2 . VAL D 3 19  ? 13.723  -3.727  25.840  1.00 42.22  ? 19  VAL L CG2 1 
ATOM   3991 N N   . THR D 3 20  ? 11.753  -7.894  25.264  1.00 47.61  ? 20  THR L N   1 
ATOM   3992 C CA  . THR D 3 20  ? 11.672  -9.322  24.970  1.00 45.83  ? 20  THR L CA  1 
ATOM   3993 C C   . THR D 3 20  ? 11.643  -9.515  23.462  1.00 50.81  ? 20  THR L C   1 
ATOM   3994 O O   . THR D 3 20  ? 10.722  -9.038  22.792  1.00 47.08  ? 20  THR L O   1 
ATOM   3995 C CB  . THR D 3 20  ? 10.435  -9.955  25.615  1.00 48.89  ? 20  THR L CB  1 
ATOM   3996 O OG1 . THR D 3 20  ? 10.482  -9.763  27.035  1.00 55.82  ? 20  THR L OG1 1 
ATOM   3997 C CG2 . THR D 3 20  ? 10.380  -11.445 25.313  1.00 45.51  ? 20  THR L CG2 1 
ATOM   3998 N N   . LEU D 3 21  ? 12.646  -10.213 22.935  1.00 47.20  ? 21  LEU L N   1 
ATOM   3999 C CA  . LEU D 3 21  ? 12.752  -10.538 21.518  1.00 51.29  ? 21  LEU L CA  1 
ATOM   4000 C C   . LEU D 3 21  ? 12.467  -12.024 21.334  1.00 48.96  ? 21  LEU L C   1 
ATOM   4001 O O   . LEU D 3 21  ? 13.080  -12.856 22.013  1.00 48.29  ? 21  LEU L O   1 
ATOM   4002 C CB  . LEU D 3 21  ? 14.152  -10.200 21.000  1.00 50.01  ? 21  LEU L CB  1 
ATOM   4003 C CG  . LEU D 3 21  ? 14.615  -8.753  21.199  1.00 49.33  ? 21  LEU L CG  1 
ATOM   4004 C CD1 . LEU D 3 21  ? 15.908  -8.478  20.438  1.00 41.07  ? 21  LEU L CD1 1 
ATOM   4005 C CD2 . LEU D 3 21  ? 13.529  -7.751  20.826  1.00 43.94  ? 21  LEU L CD2 1 
ATOM   4006 N N   . THR D 3 22  ? 11.553  -12.362 20.423  1.00 47.81  ? 22  THR L N   1 
ATOM   4007 C CA  . THR D 3 22  ? 11.115  -13.739 20.236  1.00 51.82  ? 22  THR L CA  1 
ATOM   4008 C C   . THR D 3 22  ? 11.694  -14.317 18.948  1.00 51.96  ? 22  THR L C   1 
ATOM   4009 O O   . THR D 3 22  ? 11.725  -13.643 17.915  1.00 52.20  ? 22  THR L O   1 
ATOM   4010 C CB  . THR D 3 22  ? 9.585   -13.816 20.200  1.00 48.85  ? 22  THR L CB  1 
ATOM   4011 O OG1 . THR D 3 22  ? 9.048   -13.200 21.377  1.00 52.81  ? 22  THR L OG1 1 
ATOM   4012 C CG2 . THR D 3 22  ? 9.118   -15.262 20.138  1.00 51.53  ? 22  THR L CG2 1 
ATOM   4013 N N   . CYS D 3 23  ? 12.151  -15.569 19.016  1.00 48.11  ? 23  CYS L N   1 
ATOM   4014 C CA  . CYS D 3 23  ? 12.646  -16.318 17.863  1.00 52.81  ? 23  CYS L CA  1 
ATOM   4015 C C   . CYS D 3 23  ? 11.851  -17.616 17.742  1.00 54.13  ? 23  CYS L C   1 
ATOM   4016 O O   . CYS D 3 23  ? 12.008  -18.524 18.568  1.00 62.40  ? 23  CYS L O   1 
ATOM   4017 C CB  . CYS D 3 23  ? 14.143  -16.601 17.995  1.00 48.78  ? 23  CYS L CB  1 
ATOM   4018 S SG  . CYS D 3 23  ? 14.904  -17.459 16.588  1.00 51.03  ? 23  CYS L SG  1 
ATOM   4019 N N   . SER D 3 24  ? 10.968  -17.681 16.747  1.00 52.98  ? 24  SER L N   1 
ATOM   4020 C CA  . SER D 3 24  ? 10.204  -18.884 16.447  1.00 55.94  ? 24  SER L CA  1 
ATOM   4021 C C   . SER D 3 24  ? 10.931  -19.719 15.400  1.00 54.67  ? 24  SER L C   1 
ATOM   4022 O O   . SER D 3 24  ? 11.534  -19.179 14.469  1.00 57.65  ? 24  SER L O   1 
ATOM   4023 C CB  . SER D 3 24  ? 8.801   -18.526 15.952  1.00 57.28  ? 24  SER L CB  1 
ATOM   4024 O OG  . SER D 3 24  ? 8.150   -19.658 15.404  1.00 65.76  ? 24  SER L OG  1 
ATOM   4025 N N   . ALA D 3 25  ? 10.881  -21.039 15.560  1.00 54.95  ? 25  ALA L N   1 
ATOM   4026 C CA  . ALA D 3 25  ? 11.542  -21.961 14.647  1.00 56.65  ? 25  ALA L CA  1 
ATOM   4027 C C   . ALA D 3 25  ? 10.510  -22.862 13.982  1.00 56.39  ? 25  ALA L C   1 
ATOM   4028 O O   . ALA D 3 25  ? 9.539   -23.286 14.618  1.00 62.69  ? 25  ALA L O   1 
ATOM   4029 C CB  . ALA D 3 25  ? 12.590  -22.808 15.375  1.00 50.80  ? 25  ALA L CB  1 
ATOM   4030 N N   . SER D 3 26  ? 10.726  -23.153 12.695  1.00 57.24  ? 26  SER L N   1 
ATOM   4031 C CA  . SER D 3 26  ? 9.793   -23.989 11.947  1.00 66.48  ? 26  SER L CA  1 
ATOM   4032 C C   . SER D 3 26  ? 9.838   -25.447 12.385  1.00 66.96  ? 26  SER L C   1 
ATOM   4033 O O   . SER D 3 26  ? 8.896   -26.195 12.104  1.00 68.02  ? 26  SER L O   1 
ATOM   4034 C CB  . SER D 3 26  ? 10.077  -23.883 10.447  1.00 59.84  ? 26  SER L CB  1 
ATOM   4035 O OG  . SER D 3 26  ? 11.404  -24.278 10.145  1.00 64.06  ? 26  SER L OG  1 
ATOM   4036 N N   . SER D 3 27  ? 10.909  -25.867 13.053  1.00 66.25  ? 27  SER L N   1 
ATOM   4037 C CA  . SER D 3 27  ? 10.993  -27.189 13.655  1.00 63.89  ? 27  SER L CA  1 
ATOM   4038 C C   . SER D 3 27  ? 11.619  -27.047 15.033  1.00 60.79  ? 27  SER L C   1 
ATOM   4039 O O   . SER D 3 27  ? 12.186  -26.006 15.376  1.00 64.04  ? 27  SER L O   1 
ATOM   4040 C CB  . SER D 3 27  ? 11.800  -28.162 12.785  1.00 62.95  ? 27  SER L CB  1 
ATOM   4041 O OG  . SER D 3 27  ? 11.115  -28.461 11.581  1.00 71.50  ? 27  SER L OG  1 
ATOM   4042 N N   . SER D 3 28  ? 11.508  -28.103 15.833  1.00 57.66  ? 29  SER L N   1 
ATOM   4043 C CA  . SER D 3 28  ? 12.077  -28.076 17.173  1.00 60.61  ? 29  SER L CA  1 
ATOM   4044 C C   . SER D 3 28  ? 13.599  -28.033 17.101  1.00 58.96  ? 29  SER L C   1 
ATOM   4045 O O   . SER D 3 28  ? 14.217  -28.683 16.253  1.00 58.13  ? 29  SER L O   1 
ATOM   4046 C CB  . SER D 3 28  ? 11.616  -29.291 17.975  1.00 65.18  ? 29  SER L CB  1 
ATOM   4047 O OG  . SER D 3 28  ? 12.162  -29.278 19.283  1.00 65.02  ? 29  SER L OG  1 
ATOM   4048 N N   . VAL D 3 29  ? 14.201  -27.253 17.995  1.00 63.91  ? 30  VAL L N   1 
ATOM   4049 C CA  . VAL D 3 29  ? 15.643  -27.047 18.022  1.00 64.18  ? 30  VAL L CA  1 
ATOM   4050 C C   . VAL D 3 29  ? 16.133  -27.211 19.455  1.00 63.27  ? 30  VAL L C   1 
ATOM   4051 O O   . VAL D 3 29  ? 15.475  -26.766 20.403  1.00 62.60  ? 30  VAL L O   1 
ATOM   4052 C CB  . VAL D 3 29  ? 16.026  -25.664 17.449  1.00 57.79  ? 30  VAL L CB  1 
ATOM   4053 C CG1 . VAL D 3 29  ? 15.202  -24.567 18.097  1.00 57.81  ? 30  VAL L CG1 1 
ATOM   4054 C CG2 . VAL D 3 29  ? 17.515  -25.396 17.616  1.00 58.52  ? 30  VAL L CG2 1 
ATOM   4055 N N   . SER D 3 30  ? 17.289  -27.861 19.609  1.00 63.55  ? 31  SER L N   1 
ATOM   4056 C CA  . SER D 3 30  ? 17.808  -28.164 20.940  1.00 58.47  ? 31  SER L CA  1 
ATOM   4057 C C   . SER D 3 30  ? 18.237  -26.897 21.670  1.00 60.78  ? 31  SER L C   1 
ATOM   4058 O O   . SER D 3 30  ? 17.802  -26.642 22.800  1.00 61.06  ? 31  SER L O   1 
ATOM   4059 C CB  . SER D 3 30  ? 18.976  -29.143 20.829  1.00 63.07  ? 31  SER L CB  1 
ATOM   4060 O OG  . SER D 3 30  ? 18.740  -30.104 19.814  1.00 68.41  ? 31  SER L OG  1 
ATOM   4061 N N   . TYR D 3 31  ? 19.095  -26.094 21.044  1.00 59.42  ? 32  TYR L N   1 
ATOM   4062 C CA  . TYR D 3 31  ? 19.619  -24.880 21.650  1.00 58.39  ? 32  TYR L CA  1 
ATOM   4063 C C   . TYR D 3 31  ? 19.547  -23.732 20.654  1.00 58.23  ? 32  TYR L C   1 
ATOM   4064 O O   . TYR D 3 31  ? 19.712  -23.925 19.446  1.00 57.69  ? 32  TYR L O   1 
ATOM   4065 C CB  . TYR D 3 31  ? 21.075  -25.058 22.114  1.00 59.99  ? 32  TYR L CB  1 
ATOM   4066 C CG  . TYR D 3 31  ? 21.339  -26.328 22.895  1.00 62.88  ? 32  TYR L CG  1 
ATOM   4067 C CD1 . TYR D 3 31  ? 21.713  -27.499 22.248  1.00 62.53  ? 32  TYR L CD1 1 
ATOM   4068 C CD2 . TYR D 3 31  ? 21.230  -26.352 24.279  1.00 60.03  ? 32  TYR L CD2 1 
ATOM   4069 C CE1 . TYR D 3 31  ? 21.959  -28.661 22.956  1.00 66.40  ? 32  TYR L CE1 1 
ATOM   4070 C CE2 . TYR D 3 31  ? 21.476  -27.508 24.996  1.00 64.12  ? 32  TYR L CE2 1 
ATOM   4071 C CZ  . TYR D 3 31  ? 21.840  -28.659 24.330  1.00 65.46  ? 32  TYR L CZ  1 
ATOM   4072 O OH  . TYR D 3 31  ? 22.085  -29.812 25.039  1.00 69.32  ? 32  TYR L OH  1 
ATOM   4073 N N   . MET D 3 32  ? 19.302  -22.533 21.173  1.00 52.86  ? 33  MET L N   1 
ATOM   4074 C CA  . MET D 3 32  ? 19.326  -21.312 20.383  1.00 55.26  ? 33  MET L CA  1 
ATOM   4075 C C   . MET D 3 32  ? 20.529  -20.463 20.772  1.00 48.15  ? 33  MET L C   1 
ATOM   4076 O O   . MET D 3 32  ? 20.957  -20.453 21.929  1.00 46.82  ? 33  MET L O   1 
ATOM   4077 C CB  . MET D 3 32  ? 18.036  -20.504 20.567  1.00 52.72  ? 33  MET L CB  1 
ATOM   4078 C CG  . MET D 3 32  ? 17.695  -19.602 19.387  1.00 50.23  ? 33  MET L CG  1 
ATOM   4079 S SD  . MET D 3 32  ? 17.756  -20.432 17.788  1.00 52.58  ? 33  MET L SD  1 
ATOM   4080 C CE  . MET D 3 32  ? 16.026  -20.840 17.551  1.00 51.80  ? 33  MET L CE  1 
ATOM   4081 N N   . HIS D 3 33  ? 21.071  -19.747 19.792  1.00 49.35  ? 34  HIS L N   1 
ATOM   4082 C CA  . HIS D 3 33  ? 22.160  -18.807 20.011  1.00 44.09  ? 34  HIS L CA  1 
ATOM   4083 C C   . HIS D 3 33  ? 21.719  -17.409 19.602  1.00 43.66  ? 34  HIS L C   1 
ATOM   4084 O O   . HIS D 3 33  ? 20.861  -17.244 18.734  1.00 43.96  ? 34  HIS L O   1 
ATOM   4085 C CB  . HIS D 3 33  ? 23.414  -19.219 19.229  1.00 44.92  ? 34  HIS L CB  1 
ATOM   4086 C CG  . HIS D 3 33  ? 23.897  -20.600 19.546  1.00 48.28  ? 34  HIS L CG  1 
ATOM   4087 N ND1 . HIS D 3 33  ? 25.065  -20.841 20.238  1.00 48.44  ? 34  HIS L ND1 1 
ATOM   4088 C CD2 . HIS D 3 33  ? 23.363  -21.815 19.276  1.00 45.35  ? 34  HIS L CD2 1 
ATOM   4089 C CE1 . HIS D 3 33  ? 25.234  -22.145 20.371  1.00 47.52  ? 34  HIS L CE1 1 
ATOM   4090 N NE2 . HIS D 3 33  ? 24.214  -22.758 19.798  1.00 47.29  ? 34  HIS L NE2 1 
ATOM   4091 N N   . TRP D 3 34  ? 22.302  -16.402 20.247  1.00 39.99  ? 35  TRP L N   1 
ATOM   4092 C CA  . TRP D 3 34  ? 21.967  -15.009 19.994  1.00 36.71  ? 35  TRP L CA  1 
ATOM   4093 C C   . TRP D 3 34  ? 23.244  -14.204 19.826  1.00 35.16  ? 35  TRP L C   1 
ATOM   4094 O O   . TRP D 3 34  ? 24.135  -14.264 20.682  1.00 33.99  ? 35  TRP L O   1 
ATOM   4095 C CB  . TRP D 3 34  ? 21.130  -14.418 21.132  1.00 36.17  ? 35  TRP L CB  1 
ATOM   4096 C CG  . TRP D 3 34  ? 19.814  -15.094 21.336  1.00 43.17  ? 35  TRP L CG  1 
ATOM   4097 C CD1 . TRP D 3 34  ? 19.586  -16.254 22.015  1.00 43.48  ? 35  TRP L CD1 1 
ATOM   4098 C CD2 . TRP D 3 34  ? 18.540  -14.653 20.853  1.00 43.58  ? 35  TRP L CD2 1 
ATOM   4099 N NE1 . TRP D 3 34  ? 18.248  -16.562 21.990  1.00 47.39  ? 35  TRP L NE1 1 
ATOM   4100 C CE2 . TRP D 3 34  ? 17.584  -15.596 21.280  1.00 41.91  ? 35  TRP L CE2 1 
ATOM   4101 C CE3 . TRP D 3 34  ? 18.114  -13.553 20.102  1.00 37.26  ? 35  TRP L CE3 1 
ATOM   4102 C CZ2 . TRP D 3 34  ? 16.228  -15.471 20.981  1.00 46.05  ? 35  TRP L CZ2 1 
ATOM   4103 C CZ3 . TRP D 3 34  ? 16.769  -13.433 19.806  1.00 45.10  ? 35  TRP L CZ3 1 
ATOM   4104 C CH2 . TRP D 3 34  ? 15.842  -14.385 20.246  1.00 47.34  ? 35  TRP L CH2 1 
ATOM   4105 N N   . PHE D 3 35  ? 23.307  -13.436 18.739  1.00 32.98  ? 36  PHE L N   1 
ATOM   4106 C CA  . PHE D 3 35  ? 24.413  -12.542 18.429  1.00 31.36  ? 36  PHE L CA  1 
ATOM   4107 C C   . PHE D 3 35  ? 23.926  -11.101 18.386  1.00 30.47  ? 36  PHE L C   1 
ATOM   4108 O O   . PHE D 3 35  ? 22.823  -10.819 17.903  1.00 34.94  ? 36  PHE L O   1 
ATOM   4109 C CB  . PHE D 3 35  ? 25.070  -12.889 17.085  1.00 28.08  ? 36  PHE L CB  1 
ATOM   4110 C CG  . PHE D 3 35  ? 25.641  -14.275 17.020  1.00 27.18  ? 36  PHE L CG  1 
ATOM   4111 C CD1 . PHE D 3 35  ? 24.829  -15.374 16.798  1.00 32.15  ? 36  PHE L CD1 1 
ATOM   4112 C CD2 . PHE D 3 35  ? 27.004  -14.472 17.161  1.00 29.59  ? 36  PHE L CD2 1 
ATOM   4113 C CE1 . PHE D 3 35  ? 25.367  -16.648 16.736  1.00 31.84  ? 36  PHE L CE1 1 
ATOM   4114 C CE2 . PHE D 3 35  ? 27.547  -15.738 17.098  1.00 36.31  ? 36  PHE L CE2 1 
ATOM   4115 C CZ  . PHE D 3 35  ? 26.729  -16.828 16.884  1.00 33.20  ? 36  PHE L CZ  1 
ATOM   4116 N N   . GLN D 3 36  ? 24.755  -10.195 18.897  1.00 31.26  ? 37  GLN L N   1 
ATOM   4117 C CA  . GLN D 3 36  ? 24.517  -8.762  18.816  1.00 32.19  ? 37  GLN L CA  1 
ATOM   4118 C C   . GLN D 3 36  ? 25.413  -8.149  17.748  1.00 32.40  ? 37  GLN L C   1 
ATOM   4119 O O   . GLN D 3 36  ? 26.593  -8.494  17.641  1.00 31.24  ? 37  GLN L O   1 
ATOM   4120 C CB  . GLN D 3 36  ? 24.780  -8.092  20.166  1.00 35.44  ? 37  GLN L CB  1 
ATOM   4121 C CG  . GLN D 3 36  ? 24.546  -6.589  20.183  1.00 34.84  ? 37  GLN L CG  1 
ATOM   4122 C CD  . GLN D 3 36  ? 25.241  -5.909  21.346  1.00 30.18  ? 37  GLN L CD  1 
ATOM   4123 O OE1 . GLN D 3 36  ? 26.470  -5.856  21.403  1.00 33.51  ? 37  GLN L OE1 1 
ATOM   4124 N NE2 . GLN D 3 36  ? 24.457  -5.387  22.282  1.00 32.00  ? 37  GLN L NE2 1 
ATOM   4125 N N   . GLN D 3 37  ? 24.848  -7.240  16.958  1.00 32.29  ? 38  GLN L N   1 
ATOM   4126 C CA  . GLN D 3 37  ? 25.616  -6.522  15.950  1.00 35.40  ? 38  GLN L CA  1 
ATOM   4127 C C   . GLN D 3 37  ? 25.222  -5.057  15.964  1.00 33.41  ? 38  GLN L C   1 
ATOM   4128 O O   . GLN D 3 37  ? 24.038  -4.726  15.865  1.00 33.40  ? 38  GLN L O   1 
ATOM   4129 C CB  . GLN D 3 37  ? 25.404  -7.094  14.542  1.00 28.37  ? 38  GLN L CB  1 
ATOM   4130 C CG  . GLN D 3 37  ? 26.187  -6.329  13.477  1.00 31.58  ? 38  GLN L CG  1 
ATOM   4131 C CD  . GLN D 3 37  ? 25.998  -6.883  12.082  1.00 33.58  ? 38  GLN L CD  1 
ATOM   4132 O OE1 . GLN D 3 37  ? 24.885  -7.215  11.677  1.00 24.40  ? 38  GLN L OE1 1 
ATOM   4133 N NE2 . GLN D 3 37  ? 27.090  -6.980  11.333  1.00 29.70  ? 38  GLN L NE2 1 
ATOM   4134 N N   . LYS D 3 38  ? 26.211  -4.186  16.094  1.00 32.51  ? 39  LYS L N   1 
ATOM   4135 C CA  . LYS D 3 38  ? 26.007  -2.765  15.880  1.00 38.83  ? 39  LYS L CA  1 
ATOM   4136 C C   . LYS D 3 38  ? 26.442  -2.406  14.465  1.00 41.29  ? 39  LYS L C   1 
ATOM   4137 O O   . LYS D 3 38  ? 27.247  -3.107  13.846  1.00 39.47  ? 39  LYS L O   1 
ATOM   4138 C CB  . LYS D 3 38  ? 26.774  -1.950  16.924  1.00 35.90  ? 39  LYS L CB  1 
ATOM   4139 C CG  . LYS D 3 38  ? 26.365  -2.319  18.344  1.00 33.81  ? 39  LYS L CG  1 
ATOM   4140 C CD  . LYS D 3 38  ? 26.828  -1.312  19.380  1.00 39.35  ? 39  LYS L CD  1 
ATOM   4141 C CE  . LYS D 3 38  ? 26.294  -1.690  20.755  1.00 36.33  ? 39  LYS L CE  1 
ATOM   4142 N NZ  . LYS D 3 38  ? 26.604  -0.674  21.793  1.00 40.56  ? 39  LYS L NZ  1 
ATOM   4143 N N   . SER D 3 39  ? 25.874  -1.315  13.952  1.00 43.28  ? 40  SER L N   1 
ATOM   4144 C CA  . SER D 3 39  ? 26.046  -0.933  12.554  1.00 40.18  ? 40  SER L CA  1 
ATOM   4145 C C   . SER D 3 39  ? 27.515  -0.925  12.158  1.00 43.88  ? 40  SER L C   1 
ATOM   4146 O O   . SER D 3 39  ? 28.336  -0.266  12.798  1.00 39.77  ? 40  SER L O   1 
ATOM   4147 C CB  . SER D 3 39  ? 25.423  0.444   12.314  1.00 47.94  ? 40  SER L CB  1 
ATOM   4148 O OG  . SER D 3 39  ? 25.508  0.810   10.948  1.00 50.74  ? 40  SER L OG  1 
ATOM   4149 N N   . GLY D 3 40  ? 27.848  -1.699  11.126  1.00 38.92  ? 41  GLY L N   1 
ATOM   4150 C CA  . GLY D 3 40  ? 29.180  -1.700  10.561  1.00 43.10  ? 41  GLY L CA  1 
ATOM   4151 C C   . GLY D 3 40  ? 30.174  -2.621  11.234  1.00 45.05  ? 41  GLY L C   1 
ATOM   4152 O O   . GLY D 3 40  ? 31.245  -2.868  10.664  1.00 40.36  ? 41  GLY L O   1 
ATOM   4153 N N   . THR D 3 41  ? 29.864  -3.134  12.419  1.00 43.43  ? 42  THR L N   1 
ATOM   4154 C CA  . THR D 3 41  ? 30.788  -3.959  13.183  1.00 37.15  ? 42  THR L CA  1 
ATOM   4155 C C   . THR D 3 41  ? 30.436  -5.438  13.062  1.00 38.63  ? 42  THR L C   1 
ATOM   4156 O O   . THR D 3 41  ? 29.337  -5.813  12.645  1.00 39.93  ? 42  THR L O   1 
ATOM   4157 C CB  . THR D 3 41  ? 30.796  -3.542  14.657  1.00 40.81  ? 42  THR L CB  1 
ATOM   4158 O OG1 . THR D 3 41  ? 29.480  -3.685  15.205  1.00 38.74  ? 42  THR L OG1 1 
ATOM   4159 C CG2 . THR D 3 41  ? 31.248  -2.096  14.796  1.00 39.10  ? 42  THR L CG2 1 
ATOM   4160 N N   . SER D 3 42  ? 31.401  -6.277  13.431  1.00 34.24  ? 43  SER L N   1 
ATOM   4161 C CA  . SER D 3 42  ? 31.221  -7.719  13.348  1.00 41.26  ? 43  SER L CA  1 
ATOM   4162 C C   . SER D 3 42  ? 30.192  -8.194  14.372  1.00 35.67  ? 43  SER L C   1 
ATOM   4163 O O   . SER D 3 42  ? 30.108  -7.641  15.473  1.00 33.18  ? 43  SER L O   1 
ATOM   4164 C CB  . SER D 3 42  ? 32.548  -8.436  13.584  1.00 39.00  ? 43  SER L CB  1 
ATOM   4165 O OG  . SER D 3 42  ? 33.468  -8.177  12.540  1.00 43.35  ? 43  SER L OG  1 
ATOM   4166 N N   . PRO D 3 43  ? 29.391  -9.205  14.038  1.00 34.96  ? 44  PRO L N   1 
ATOM   4167 C CA  . PRO D 3 43  ? 28.499  -9.799  15.041  1.00 30.28  ? 44  PRO L CA  1 
ATOM   4168 C C   . PRO D 3 43  ? 29.296  -10.427 16.174  1.00 37.18  ? 44  PRO L C   1 
ATOM   4169 O O   . PRO D 3 43  ? 30.352  -11.027 15.959  1.00 38.94  ? 44  PRO L O   1 
ATOM   4170 C CB  . PRO D 3 43  ? 27.717  -10.854 14.249  1.00 30.68  ? 44  PRO L CB  1 
ATOM   4171 C CG  . PRO D 3 43  ? 27.865  -10.456 12.814  1.00 31.82  ? 44  PRO L CG  1 
ATOM   4172 C CD  . PRO D 3 43  ? 29.212  -9.811  12.708  1.00 32.76  ? 44  PRO L CD  1 
ATOM   4173 N N   . LYS D 3 44  ? 28.777  -10.288 17.391  1.00 31.24  ? 45  LYS L N   1 
ATOM   4174 C CA  . LYS D 3 44  ? 29.423  -10.804 18.591  1.00 37.31  ? 45  LYS L CA  1 
ATOM   4175 C C   . LYS D 3 44  ? 28.531  -11.848 19.244  1.00 35.86  ? 45  LYS L C   1 
ATOM   4176 O O   . LYS D 3 44  ? 27.325  -11.626 19.400  1.00 28.04  ? 45  LYS L O   1 
ATOM   4177 C CB  . LYS D 3 44  ? 29.716  -9.677  19.584  1.00 32.99  ? 45  LYS L CB  1 
ATOM   4178 C CG  . LYS D 3 44  ? 30.181  -8.378  18.950  1.00 35.54  ? 45  LYS L CG  1 
ATOM   4179 C CD  . LYS D 3 44  ? 30.435  -7.322  20.013  1.00 41.43  ? 45  LYS L CD  1 
ATOM   4180 C CE  . LYS D 3 44  ? 31.584  -6.407  19.624  1.00 50.44  ? 45  LYS L CE  1 
ATOM   4181 N NZ  . LYS D 3 44  ? 31.917  -5.436  20.707  1.00 41.04  ? 45  LYS L NZ  1 
ATOM   4182 N N   . ARG D 3 45  ? 29.121  -12.984 19.617  1.00 33.86  ? 46  ARG L N   1 
ATOM   4183 C CA  . ARG D 3 45  ? 28.385  -13.986 20.377  1.00 35.02  ? 46  ARG L CA  1 
ATOM   4184 C C   . ARG D 3 45  ? 27.891  -13.384 21.684  1.00 38.36  ? 46  ARG L C   1 
ATOM   4185 O O   . ARG D 3 45  ? 28.674  -12.839 22.468  1.00 31.84  ? 46  ARG L O   1 
ATOM   4186 C CB  . ARG D 3 45  ? 29.260  -15.207 20.659  1.00 34.89  ? 46  ARG L CB  1 
ATOM   4187 C CG  . ARG D 3 45  ? 28.485  -16.372 21.261  1.00 39.38  ? 46  ARG L CG  1 
ATOM   4188 C CD  . ARG D 3 45  ? 29.387  -17.538 21.644  1.00 41.12  ? 46  ARG L CD  1 
ATOM   4189 N NE  . ARG D 3 45  ? 30.335  -17.195 22.699  1.00 38.55  ? 46  ARG L NE  1 
ATOM   4190 C CZ  . ARG D 3 45  ? 30.973  -18.081 23.451  1.00 43.40  ? 46  ARG L CZ  1 
ATOM   4191 N NH1 . ARG D 3 45  ? 30.772  -19.381 23.308  1.00 38.23  ? 46  ARG L NH1 1 
ATOM   4192 N NH2 . ARG D 3 45  ? 31.833  -17.653 24.371  1.00 39.94  ? 46  ARG L NH2 1 
ATOM   4193 N N   . TRP D 3 46  ? 26.585  -13.478 21.914  1.00 33.58  ? 47  TRP L N   1 
ATOM   4194 C CA  . TRP D 3 46  ? 25.958  -12.826 23.055  1.00 36.70  ? 47  TRP L CA  1 
ATOM   4195 C C   . TRP D 3 46  ? 25.369  -13.826 24.035  1.00 42.64  ? 47  TRP L C   1 
ATOM   4196 O O   . TRP D 3 46  ? 25.652  -13.749 25.237  1.00 40.01  ? 47  TRP L O   1 
ATOM   4197 C CB  . TRP D 3 46  ? 24.873  -11.854 22.560  1.00 36.23  ? 47  TRP L CB  1 
ATOM   4198 C CG  . TRP D 3 46  ? 24.738  -10.620 23.392  1.00 34.04  ? 47  TRP L CG  1 
ATOM   4199 C CD1 . TRP D 3 46  ? 23.671  -10.257 24.160  1.00 33.21  ? 47  TRP L CD1 1 
ATOM   4200 C CD2 . TRP D 3 46  ? 25.709  -9.576  23.533  1.00 31.59  ? 47  TRP L CD2 1 
ATOM   4201 N NE1 . TRP D 3 46  ? 23.918  -9.051  24.771  1.00 35.59  ? 47  TRP L NE1 1 
ATOM   4202 C CE2 . TRP D 3 46  ? 25.163  -8.612  24.403  1.00 34.51  ? 47  TRP L CE2 1 
ATOM   4203 C CE3 . TRP D 3 46  ? 26.987  -9.363  23.008  1.00 33.51  ? 47  TRP L CE3 1 
ATOM   4204 C CZ2 . TRP D 3 46  ? 25.852  -7.455  24.762  1.00 37.95  ? 47  TRP L CZ2 1 
ATOM   4205 C CZ3 . TRP D 3 46  ? 27.667  -8.213  23.363  1.00 32.78  ? 47  TRP L CZ3 1 
ATOM   4206 C CH2 . TRP D 3 46  ? 27.100  -7.275  24.233  1.00 31.96  ? 47  TRP L CH2 1 
ATOM   4207 N N   . ILE D 3 47  ? 24.554  -14.766 23.557  1.00 37.31  ? 48  ILE L N   1 
ATOM   4208 C CA  . ILE D 3 47  ? 23.972  -15.806 24.405  1.00 42.31  ? 48  ILE L CA  1 
ATOM   4209 C C   . ILE D 3 47  ? 24.061  -17.135 23.667  1.00 47.64  ? 48  ILE L C   1 
ATOM   4210 O O   . ILE D 3 47  ? 23.310  -17.366 22.716  1.00 51.02  ? 48  ILE L O   1 
ATOM   4211 C CB  . ILE D 3 47  ? 22.512  -15.512 24.790  1.00 43.68  ? 48  ILE L CB  1 
ATOM   4212 C CG1 . ILE D 3 47  ? 22.391  -14.164 25.502  1.00 43.19  ? 48  ILE L CG1 1 
ATOM   4213 C CG2 . ILE D 3 47  ? 21.950  -16.637 25.650  1.00 47.45  ? 48  ILE L CG2 1 
ATOM   4214 C CD1 . ILE D 3 47  ? 20.964  -13.734 25.751  1.00 40.29  ? 48  ILE L CD1 1 
ATOM   4215 N N   . TYR D 3 48  ? 24.954  -18.014 24.107  1.00 45.97  ? 49  TYR L N   1 
ATOM   4216 C CA  . TYR D 3 48  ? 25.104  -19.318 23.478  1.00 45.26  ? 49  TYR L CA  1 
ATOM   4217 C C   . TYR D 3 48  ? 24.454  -20.394 24.342  1.00 47.77  ? 49  TYR L C   1 
ATOM   4218 O O   . TYR D 3 48  ? 24.308  -20.244 25.557  1.00 44.71  ? 49  TYR L O   1 
ATOM   4219 C CB  . TYR D 3 48  ? 26.578  -19.665 23.228  1.00 43.11  ? 49  TYR L CB  1 
ATOM   4220 C CG  . TYR D 3 48  ? 27.469  -19.667 24.455  1.00 42.23  ? 49  TYR L CG  1 
ATOM   4221 C CD1 . TYR D 3 48  ? 27.724  -18.501 25.165  1.00 45.98  ? 49  TYR L CD1 1 
ATOM   4222 C CD2 . TYR D 3 48  ? 28.051  -20.845 24.904  1.00 45.82  ? 49  TYR L CD2 1 
ATOM   4223 C CE1 . TYR D 3 48  ? 28.536  -18.507 26.281  1.00 48.81  ? 49  TYR L CE1 1 
ATOM   4224 C CE2 . TYR D 3 48  ? 28.863  -20.861 26.021  1.00 41.81  ? 49  TYR L CE2 1 
ATOM   4225 C CZ  . TYR D 3 48  ? 29.103  -19.689 26.705  1.00 47.23  ? 49  TYR L CZ  1 
ATOM   4226 O OH  . TYR D 3 48  ? 29.912  -19.702 27.818  1.00 51.40  ? 49  TYR L OH  1 
ATOM   4227 N N   . ASP D 3 49  ? 24.064  -21.488 23.687  1.00 52.09  ? 50  ASP L N   1 
ATOM   4228 C CA  . ASP D 3 49  ? 23.378  -22.604 24.338  1.00 53.65  ? 50  ASP L CA  1 
ATOM   4229 C C   . ASP D 3 49  ? 22.158  -22.118 25.119  1.00 53.90  ? 50  ASP L C   1 
ATOM   4230 O O   . ASP D 3 49  ? 22.006  -22.377 26.315  1.00 50.80  ? 50  ASP L O   1 
ATOM   4231 C CB  . ASP D 3 49  ? 24.334  -23.392 25.235  1.00 49.54  ? 50  ASP L CB  1 
ATOM   4232 C CG  . ASP D 3 49  ? 25.523  -23.946 24.475  1.00 50.46  ? 50  ASP L CG  1 
ATOM   4233 O OD1 . ASP D 3 49  ? 25.385  -24.209 23.262  1.00 51.31  ? 50  ASP L OD1 1 
ATOM   4234 O OD2 . ASP D 3 49  ? 26.594  -24.122 25.091  1.00 44.88  ? 50  ASP L OD2 1 
ATOM   4235 N N   . THR D 3 50  ? 21.298  -21.374 24.420  1.00 51.29  ? 51  THR L N   1 
ATOM   4236 C CA  . THR D 3 50  ? 19.999  -20.917 24.911  1.00 46.74  ? 51  THR L CA  1 
ATOM   4237 C C   . THR D 3 50  ? 20.099  -19.875 26.023  1.00 44.96  ? 51  THR L C   1 
ATOM   4238 O O   . THR D 3 50  ? 19.458  -18.822 25.937  1.00 50.99  ? 51  THR L O   1 
ATOM   4239 C CB  . THR D 3 50  ? 19.152  -22.103 25.385  1.00 49.08  ? 51  THR L CB  1 
ATOM   4240 O OG1 . THR D 3 50  ? 18.966  -23.020 24.301  1.00 53.48  ? 51  THR L OG1 1 
ATOM   4241 C CG2 . THR D 3 50  ? 17.793  -21.623 25.870  1.00 50.30  ? 51  THR L CG2 1 
ATOM   4242 N N   . SER D 3 51  ? 20.892  -20.136 27.066  1.00 43.04  ? 52  SER L N   1 
ATOM   4243 C CA  . SER D 3 51  ? 20.867  -19.284 28.247  1.00 46.52  ? 52  SER L CA  1 
ATOM   4244 C C   . SER D 3 51  ? 22.235  -18.893 28.796  1.00 48.76  ? 52  SER L C   1 
ATOM   4245 O O   . SER D 3 51  ? 22.289  -18.111 29.752  1.00 50.22  ? 52  SER L O   1 
ATOM   4246 C CB  . SER D 3 51  ? 20.061  -19.960 29.368  1.00 48.63  ? 52  SER L CB  1 
ATOM   4247 O OG  . SER D 3 51  ? 20.490  -21.296 29.574  1.00 47.64  ? 52  SER L OG  1 
ATOM   4248 N N   . LYS D 3 52  ? 23.330  -19.402 28.239  1.00 43.72  ? 53  LYS L N   1 
ATOM   4249 C CA  . LYS D 3 52  ? 24.654  -19.060 28.746  1.00 43.86  ? 53  LYS L CA  1 
ATOM   4250 C C   . LYS D 3 52  ? 25.093  -17.711 28.189  1.00 49.55  ? 53  LYS L C   1 
ATOM   4251 O O   . LYS D 3 52  ? 25.028  -17.481 26.978  1.00 52.60  ? 53  LYS L O   1 
ATOM   4252 C CB  . LYS D 3 52  ? 25.672  -20.138 28.375  1.00 49.05  ? 53  LYS L CB  1 
ATOM   4253 C CG  . LYS D 3 52  ? 25.284  -21.546 28.792  1.00 48.53  ? 53  LYS L CG  1 
ATOM   4254 C CD  . LYS D 3 52  ? 26.323  -22.551 28.321  1.00 52.38  ? 53  LYS L CD  1 
ATOM   4255 C CE  . LYS D 3 52  ? 25.932  -23.970 28.694  1.00 50.45  ? 53  LYS L CE  1 
ATOM   4256 N NZ  . LYS D 3 52  ? 26.937  -24.961 28.223  1.00 54.19  ? 53  LYS L NZ  1 
ATOM   4257 N N   . LEU D 3 53  ? 25.547  -16.825 29.071  1.00 43.03  ? 54  LEU L N   1 
ATOM   4258 C CA  . LEU D 3 53  ? 25.997  -15.497 28.673  1.00 44.09  ? 54  LEU L CA  1 
ATOM   4259 C C   . LEU D 3 53  ? 27.468  -15.541 28.280  1.00 51.40  ? 54  LEU L C   1 
ATOM   4260 O O   . LEU D 3 53  ? 28.294  -16.113 28.998  1.00 51.61  ? 54  LEU L O   1 
ATOM   4261 C CB  . LEU D 3 53  ? 25.787  -14.484 29.800  1.00 42.02  ? 54  LEU L CB  1 
ATOM   4262 C CG  . LEU D 3 53  ? 24.350  -14.106 30.163  1.00 49.13  ? 54  LEU L CG  1 
ATOM   4263 C CD1 . LEU D 3 53  ? 24.339  -12.997 31.203  1.00 48.21  ? 54  LEU L CD1 1 
ATOM   4264 C CD2 . LEU D 3 53  ? 23.576  -13.687 28.925  1.00 48.42  ? 54  LEU L CD2 1 
ATOM   4265 N N   . ALA D 3 54  ? 27.791  -14.933 27.142  1.00 43.87  ? 55  ALA L N   1 
ATOM   4266 C CA  . ALA D 3 54  ? 29.173  -14.878 26.698  1.00 44.56  ? 55  ALA L CA  1 
ATOM   4267 C C   . ALA D 3 54  ? 29.962  -13.887 27.554  1.00 48.60  ? 55  ALA L C   1 
ATOM   4268 O O   . ALA D 3 54  ? 29.408  -13.142 28.368  1.00 54.64  ? 55  ALA L O   1 
ATOM   4269 C CB  . ALA D 3 54  ? 29.249  -14.491 25.221  1.00 42.34  ? 55  ALA L CB  1 
ATOM   4270 N N   . SER D 3 55  ? 31.279  -13.887 27.361  1.00 48.15  ? 56  SER L N   1 
ATOM   4271 C CA  . SER D 3 55  ? 32.153  -13.029 28.150  1.00 47.22  ? 56  SER L CA  1 
ATOM   4272 C C   . SER D 3 55  ? 31.875  -11.561 27.849  1.00 50.62  ? 56  SER L C   1 
ATOM   4273 O O   . SER D 3 55  ? 31.822  -11.152 26.685  1.00 56.37  ? 56  SER L O   1 
ATOM   4274 C CB  . SER D 3 55  ? 33.617  -13.362 27.867  1.00 52.79  ? 56  SER L CB  1 
ATOM   4275 O OG  . SER D 3 55  ? 34.478  -12.689 28.770  1.00 59.47  ? 56  SER L OG  1 
ATOM   4276 N N   . GLY D 3 56  ? 31.700  -10.766 28.906  1.00 52.13  ? 57  GLY L N   1 
ATOM   4277 C CA  . GLY D 3 56  ? 31.438  -9.349  28.779  1.00 43.91  ? 57  GLY L CA  1 
ATOM   4278 C C   . GLY D 3 56  ? 29.977  -8.960  28.688  1.00 49.87  ? 57  GLY L C   1 
ATOM   4279 O O   . GLY D 3 56  ? 29.671  -7.761  28.725  1.00 60.74  ? 57  GLY L O   1 
ATOM   4280 N N   . VAL D 3 57  ? 29.069  -9.923  28.569  1.00 46.84  ? 58  VAL L N   1 
ATOM   4281 C CA  . VAL D 3 57  ? 27.640  -9.637  28.453  1.00 48.26  ? 58  VAL L CA  1 
ATOM   4282 C C   . VAL D 3 57  ? 27.088  -9.273  29.827  1.00 53.81  ? 58  VAL L C   1 
ATOM   4283 O O   . VAL D 3 57  ? 27.216  -10.063 30.774  1.00 51.29  ? 58  VAL L O   1 
ATOM   4284 C CB  . VAL D 3 57  ? 26.880  -10.826 27.845  1.00 44.10  ? 58  VAL L CB  1 
ATOM   4285 C CG1 . VAL D 3 57  ? 25.384  -10.554 27.844  1.00 44.36  ? 58  VAL L CG1 1 
ATOM   4286 C CG2 . VAL D 3 57  ? 27.376  -11.104 26.434  1.00 46.07  ? 58  VAL L CG2 1 
ATOM   4287 N N   . PRO D 3 58  ? 26.480  -8.096  29.985  1.00 54.76  ? 59  PRO L N   1 
ATOM   4288 C CA  . PRO D 3 58  ? 25.949  -7.704  31.295  1.00 50.65  ? 59  PRO L CA  1 
ATOM   4289 C C   . PRO D 3 58  ? 24.857  -8.648  31.779  1.00 48.98  ? 59  PRO L C   1 
ATOM   4290 O O   . PRO D 3 58  ? 24.215  -9.360  31.003  1.00 49.13  ? 59  PRO L O   1 
ATOM   4291 C CB  . PRO D 3 58  ? 25.395  -6.295  31.047  1.00 52.64  ? 59  PRO L CB  1 
ATOM   4292 C CG  . PRO D 3 58  ? 26.141  -5.800  29.849  1.00 55.02  ? 59  PRO L CG  1 
ATOM   4293 C CD  . PRO D 3 58  ? 26.370  -7.012  28.995  1.00 49.81  ? 59  PRO L CD  1 
ATOM   4294 N N   . ALA D 3 59  ? 24.652  -8.640  33.099  1.00 50.82  ? 60  ALA L N   1 
ATOM   4295 C CA  . ALA D 3 59  ? 23.713  -9.560  33.733  1.00 44.60  ? 60  ALA L CA  1 
ATOM   4296 C C   . ALA D 3 59  ? 22.258  -9.253  33.398  1.00 47.48  ? 60  ALA L C   1 
ATOM   4297 O O   . ALA D 3 59  ? 21.392  -10.102 33.634  1.00 46.75  ? 60  ALA L O   1 
ATOM   4298 C CB  . ALA D 3 59  ? 23.905  -9.542  35.250  1.00 52.44  ? 60  ALA L CB  1 
ATOM   4299 N N   . ARG D 3 60  ? 21.965  -8.066  32.861  1.00 50.59  ? 61  ARG L N   1 
ATOM   4300 C CA  . ARG D 3 60  ? 20.591  -7.736  32.500  1.00 49.44  ? 61  ARG L CA  1 
ATOM   4301 C C   . ARG D 3 60  ? 20.088  -8.541  31.307  1.00 47.30  ? 61  ARG L C   1 
ATOM   4302 O O   . ARG D 3 60  ? 18.877  -8.575  31.065  1.00 48.80  ? 61  ARG L O   1 
ATOM   4303 C CB  . ARG D 3 60  ? 20.470  -6.236  32.223  1.00 48.23  ? 61  ARG L CB  1 
ATOM   4304 C CG  . ARG D 3 60  ? 21.299  -5.742  31.053  1.00 55.95  ? 61  ARG L CG  1 
ATOM   4305 C CD  . ARG D 3 60  ? 21.342  -4.222  31.029  1.00 51.49  ? 61  ARG L CD  1 
ATOM   4306 N NE  . ARG D 3 60  ? 22.201  -3.711  29.968  1.00 48.80  ? 61  ARG L NE  1 
ATOM   4307 C CZ  . ARG D 3 60  ? 23.419  -3.222  30.162  1.00 50.72  ? 61  ARG L CZ  1 
ATOM   4308 N NH1 . ARG D 3 60  ? 23.957  -3.162  31.369  1.00 57.77  ? 61  ARG L NH1 1 
ATOM   4309 N NH2 . ARG D 3 60  ? 24.115  -2.782  29.117  1.00 50.75  ? 61  ARG L NH2 1 
ATOM   4310 N N   . PHE D 3 61  ? 20.982  -9.189  30.563  1.00 50.66  ? 62  PHE L N   1 
ATOM   4311 C CA  . PHE D 3 61  ? 20.591  -10.051 29.455  1.00 44.88  ? 62  PHE L CA  1 
ATOM   4312 C C   . PHE D 3 61  ? 20.325  -11.465 29.952  1.00 47.60  ? 62  PHE L C   1 
ATOM   4313 O O   . PHE D 3 61  ? 21.003  -11.956 30.858  1.00 50.82  ? 62  PHE L O   1 
ATOM   4314 C CB  . PHE D 3 61  ? 21.675  -10.085 28.374  1.00 44.47  ? 62  PHE L CB  1 
ATOM   4315 C CG  . PHE D 3 61  ? 21.831  -8.795  27.623  1.00 47.20  ? 62  PHE L CG  1 
ATOM   4316 C CD1 . PHE D 3 61  ? 22.672  -7.801  28.092  1.00 43.85  ? 62  PHE L CD1 1 
ATOM   4317 C CD2 . PHE D 3 61  ? 21.151  -8.585  26.435  1.00 43.94  ? 62  PHE L CD2 1 
ATOM   4318 C CE1 . PHE D 3 61  ? 22.824  -6.616  27.396  1.00 40.26  ? 62  PHE L CE1 1 
ATOM   4319 C CE2 . PHE D 3 61  ? 21.299  -7.405  25.735  1.00 39.05  ? 62  PHE L CE2 1 
ATOM   4320 C CZ  . PHE D 3 61  ? 22.135  -6.418  26.216  1.00 42.07  ? 62  PHE L CZ  1 
ATOM   4321 N N   . SER D 3 62  ? 19.330  -12.115 29.352  1.00 46.27  ? 63  SER L N   1 
ATOM   4322 C CA  . SER D 3 62  ? 19.057  -13.514 29.649  1.00 43.07  ? 63  SER L CA  1 
ATOM   4323 C C   . SER D 3 62  ? 18.422  -14.167 28.430  1.00 43.85  ? 63  SER L C   1 
ATOM   4324 O O   . SER D 3 62  ? 17.878  -13.493 27.552  1.00 46.94  ? 63  SER L O   1 
ATOM   4325 C CB  . SER D 3 62  ? 18.150  -13.671 30.877  1.00 44.70  ? 63  SER L CB  1 
ATOM   4326 O OG  . SER D 3 62  ? 16.880  -13.086 30.655  1.00 52.48  ? 63  SER L OG  1 
ATOM   4327 N N   . GLY D 3 63  ? 18.502  -15.490 28.384  1.00 44.30  ? 64  GLY L N   1 
ATOM   4328 C CA  . GLY D 3 63  ? 17.902  -16.250 27.307  1.00 46.28  ? 64  GLY L CA  1 
ATOM   4329 C C   . GLY D 3 63  ? 17.054  -17.375 27.859  1.00 48.39  ? 64  GLY L C   1 
ATOM   4330 O O   . GLY D 3 63  ? 17.363  -17.966 28.894  1.00 49.22  ? 64  GLY L O   1 
ATOM   4331 N N   . SER D 3 64  ? 15.969  -17.669 27.146  1.00 47.35  ? 65  SER L N   1 
ATOM   4332 C CA  . SER D 3 64  ? 15.035  -18.697 27.583  1.00 52.03  ? 65  SER L CA  1 
ATOM   4333 C C   . SER D 3 64  ? 14.350  -19.302 26.365  1.00 53.50  ? 65  SER L C   1 
ATOM   4334 O O   . SER D 3 64  ? 14.591  -18.896 25.226  1.00 56.73  ? 65  SER L O   1 
ATOM   4335 C CB  . SER D 3 64  ? 14.008  -18.125 28.566  1.00 55.58  ? 65  SER L CB  1 
ATOM   4336 O OG  . SER D 3 64  ? 14.641  -17.584 29.712  1.00 56.58  ? 65  SER L OG  1 
ATOM   4337 N N   . GLY D 3 65  ? 13.478  -20.266 26.618  1.00 49.46  ? 66  GLY L N   1 
ATOM   4338 C CA  . GLY D 3 65  ? 12.693  -20.903 25.581  1.00 54.23  ? 66  GLY L CA  1 
ATOM   4339 C C   . GLY D 3 65  ? 13.081  -22.359 25.376  1.00 55.28  ? 66  GLY L C   1 
ATOM   4340 O O   . GLY D 3 65  ? 14.045  -22.874 25.944  1.00 52.70  ? 66  GLY L O   1 
ATOM   4341 N N   . SER D 3 66  ? 12.288  -23.017 24.534  1.00 53.12  ? 67  SER L N   1 
ATOM   4342 C CA  . SER D 3 66  ? 12.501  -24.416 24.187  1.00 55.69  ? 67  SER L CA  1 
ATOM   4343 C C   . SER D 3 66  ? 11.692  -24.734 22.937  1.00 59.97  ? 67  SER L C   1 
ATOM   4344 O O   . SER D 3 66  ? 10.909  -23.914 22.449  1.00 60.36  ? 67  SER L O   1 
ATOM   4345 C CB  . SER D 3 66  ? 12.110  -25.351 25.339  1.00 63.54  ? 67  SER L CB  1 
ATOM   4346 O OG  . SER D 3 66  ? 12.921  -25.134 26.482  1.00 58.45  ? 67  SER L OG  1 
ATOM   4347 N N   . GLY D 3 67  ? 11.906  -25.943 22.419  1.00 60.76  ? 68  GLY L N   1 
ATOM   4348 C CA  . GLY D 3 67  ? 11.154  -26.453 21.289  1.00 63.00  ? 68  GLY L CA  1 
ATOM   4349 C C   . GLY D 3 67  ? 11.224  -25.587 20.049  1.00 64.48  ? 68  GLY L C   1 
ATOM   4350 O O   . GLY D 3 67  ? 12.214  -25.616 19.313  1.00 64.52  ? 68  GLY L O   1 
ATOM   4351 N N   . THR D 3 68  ? 10.171  -24.804 19.813  1.00 60.97  ? 69  THR L N   1 
ATOM   4352 C CA  . THR D 3 68  ? 10.077  -23.948 18.637  1.00 60.51  ? 69  THR L CA  1 
ATOM   4353 C C   . THR D 3 68  ? 10.014  -22.467 18.989  1.00 58.10  ? 69  THR L C   1 
ATOM   4354 O O   . THR D 3 68  ? 9.790   -21.641 18.097  1.00 61.67  ? 69  THR L O   1 
ATOM   4355 C CB  . THR D 3 68  ? 8.856   -24.327 17.792  1.00 58.91  ? 69  THR L CB  1 
ATOM   4356 O OG1 . THR D 3 68  ? 7.709   -24.465 18.639  1.00 66.35  ? 69  THR L OG1 1 
ATOM   4357 C CG2 . THR D 3 68  ? 9.100   -25.633 17.053  1.00 60.45  ? 69  THR L CG2 1 
ATOM   4358 N N   . SER D 3 69  ? 10.199  -22.105 20.256  1.00 54.40  ? 70  SER L N   1 
ATOM   4359 C CA  . SER D 3 69  ? 10.090  -20.711 20.671  1.00 57.23  ? 70  SER L CA  1 
ATOM   4360 C C   . SER D 3 69  ? 11.174  -20.405 21.689  1.00 58.71  ? 70  SER L C   1 
ATOM   4361 O O   . SER D 3 69  ? 11.213  -21.022 22.756  1.00 61.53  ? 70  SER L O   1 
ATOM   4362 C CB  . SER D 3 69  ? 8.707   -20.420 21.260  1.00 55.51  ? 70  SER L CB  1 
ATOM   4363 O OG  . SER D 3 69  ? 8.625   -19.089 21.740  1.00 63.39  ? 70  SER L OG  1 
ATOM   4364 N N   . TYR D 3 70  ? 12.048  -19.456 21.360  1.00 54.68  ? 71  TYR L N   1 
ATOM   4365 C CA  . TYR D 3 70  ? 13.070  -18.976 22.278  1.00 54.61  ? 71  TYR L CA  1 
ATOM   4366 C C   . TYR D 3 70  ? 12.957  -17.463 22.395  1.00 53.11  ? 71  TYR L C   1 
ATOM   4367 O O   . TYR D 3 70  ? 12.260  -16.808 21.616  1.00 53.90  ? 71  TYR L O   1 
ATOM   4368 C CB  . TYR D 3 70  ? 14.477  -19.392 21.826  1.00 55.02  ? 71  TYR L CB  1 
ATOM   4369 C CG  . TYR D 3 70  ? 14.729  -20.877 21.947  1.00 54.67  ? 71  TYR L CG  1 
ATOM   4370 C CD1 . TYR D 3 70  ? 14.226  -21.767 21.009  1.00 53.24  ? 71  TYR L CD1 1 
ATOM   4371 C CD2 . TYR D 3 70  ? 15.468  -21.388 23.005  1.00 55.60  ? 71  TYR L CD2 1 
ATOM   4372 C CE1 . TYR D 3 70  ? 14.450  -23.124 21.122  1.00 56.45  ? 71  TYR L CE1 1 
ATOM   4373 C CE2 . TYR D 3 70  ? 15.700  -22.744 23.125  1.00 56.83  ? 71  TYR L CE2 1 
ATOM   4374 C CZ  . TYR D 3 70  ? 15.191  -23.608 22.179  1.00 55.72  ? 71  TYR L CZ  1 
ATOM   4375 O OH  . TYR D 3 70  ? 15.418  -24.960 22.295  1.00 60.88  ? 71  TYR L OH  1 
ATOM   4376 N N   . SER D 3 71  ? 13.656  -16.900 23.377  1.00 47.64  ? 72  SER L N   1 
ATOM   4377 C CA  . SER D 3 71  ? 13.500  -15.485 23.673  1.00 45.61  ? 72  SER L CA  1 
ATOM   4378 C C   . SER D 3 71  ? 14.754  -14.929 24.329  1.00 47.38  ? 72  SER L C   1 
ATOM   4379 O O   . SER D 3 71  ? 15.391  -15.593 25.155  1.00 50.25  ? 72  SER L O   1 
ATOM   4380 C CB  . SER D 3 71  ? 12.287  -15.240 24.579  1.00 47.46  ? 72  SER L CB  1 
ATOM   4381 O OG  . SER D 3 71  ? 12.499  -15.777 25.873  1.00 56.30  ? 72  SER L OG  1 
ATOM   4382 N N   . LEU D 3 72  ? 15.090  -13.700 23.946  1.00 43.57  ? 73  LEU L N   1 
ATOM   4383 C CA  . LEU D 3 72  ? 16.135  -12.906 24.578  1.00 45.44  ? 73  LEU L CA  1 
ATOM   4384 C C   . LEU D 3 72  ? 15.466  -11.801 25.382  1.00 48.04  ? 73  LEU L C   1 
ATOM   4385 O O   . LEU D 3 72  ? 14.578  -11.110 24.872  1.00 48.67  ? 73  LEU L O   1 
ATOM   4386 C CB  . LEU D 3 72  ? 17.085  -12.315 23.531  1.00 43.61  ? 73  LEU L CB  1 
ATOM   4387 C CG  . LEU D 3 72  ? 18.342  -11.576 24.003  1.00 44.73  ? 73  LEU L CG  1 
ATOM   4388 C CD1 . LEU D 3 72  ? 19.477  -11.804 23.021  1.00 39.74  ? 73  LEU L CD1 1 
ATOM   4389 C CD2 . LEU D 3 72  ? 18.082  -10.083 24.167  1.00 43.39  ? 73  LEU L CD2 1 
ATOM   4390 N N   . THR D 3 73  ? 15.890  -11.627 26.631  1.00 47.05  ? 74  THR L N   1 
ATOM   4391 C CA  . THR D 3 73  ? 15.219  -10.709 27.538  1.00 49.40  ? 74  THR L CA  1 
ATOM   4392 C C   . THR D 3 73  ? 16.225  -9.743  28.141  1.00 45.77  ? 74  THR L C   1 
ATOM   4393 O O   . THR D 3 73  ? 17.288  -10.155 28.619  1.00 48.00  ? 74  THR L O   1 
ATOM   4394 C CB  . THR D 3 73  ? 14.478  -11.466 28.644  1.00 50.07  ? 74  THR L CB  1 
ATOM   4395 O OG1 . THR D 3 73  ? 13.333  -12.115 28.078  1.00 46.45  ? 74  THR L OG1 1 
ATOM   4396 C CG2 . THR D 3 73  ? 14.017  -10.509 29.738  1.00 46.56  ? 74  THR L CG2 1 
ATOM   4397 N N   . ILE D 3 74  ? 15.871  -8.462  28.113  1.00 48.14  ? 75  ILE L N   1 
ATOM   4398 C CA  . ILE D 3 74  ? 16.597  -7.394  28.786  1.00 50.09  ? 75  ILE L CA  1 
ATOM   4399 C C   . ILE D 3 74  ? 15.743  -6.936  29.961  1.00 55.47  ? 75  ILE L C   1 
ATOM   4400 O O   . ILE D 3 74  ? 14.596  -6.510  29.772  1.00 51.94  ? 75  ILE L O   1 
ATOM   4401 C CB  . ILE D 3 74  ? 16.887  -6.225  27.831  1.00 57.42  ? 75  ILE L CB  1 
ATOM   4402 C CG1 . ILE D 3 74  ? 17.996  -6.598  26.841  1.00 53.41  ? 75  ILE L CG1 1 
ATOM   4403 C CG2 . ILE D 3 74  ? 17.273  -4.977  28.590  1.00 55.62  ? 75  ILE L CG2 1 
ATOM   4404 C CD1 . ILE D 3 74  ? 18.437  -5.446  25.957  1.00 47.15  ? 75  ILE L CD1 1 
ATOM   4405 N N   . SER D 3 75  ? 16.290  -7.026  31.175  1.00 55.50  ? 76  SER L N   1 
ATOM   4406 C CA  . SER D 3 75  ? 15.536  -6.588  32.346  1.00 58.26  ? 76  SER L CA  1 
ATOM   4407 C C   . SER D 3 75  ? 15.294  -5.083  32.318  1.00 56.77  ? 76  SER L C   1 
ATOM   4408 O O   . SER D 3 75  ? 14.151  -4.628  32.430  1.00 61.54  ? 76  SER L O   1 
ATOM   4409 C CB  . SER D 3 75  ? 16.260  -6.994  33.628  1.00 49.57  ? 76  SER L CB  1 
ATOM   4410 O OG  . SER D 3 75  ? 17.508  -6.335  33.745  1.00 53.53  ? 76  SER L OG  1 
ATOM   4411 N N   . SER D 3 76  ? 16.358  -4.294  32.179  1.00 56.96  ? 77  SER L N   1 
ATOM   4412 C CA  . SER D 3 76  ? 16.258  -2.838  32.121  1.00 59.45  ? 77  SER L CA  1 
ATOM   4413 C C   . SER D 3 76  ? 17.088  -2.348  30.942  1.00 56.30  ? 77  SER L C   1 
ATOM   4414 O O   . SER D 3 76  ? 18.316  -2.478  30.947  1.00 51.30  ? 77  SER L O   1 
ATOM   4415 C CB  . SER D 3 76  ? 16.727  -2.196  33.427  1.00 57.44  ? 77  SER L CB  1 
ATOM   4416 O OG  . SER D 3 76  ? 16.637  -0.784  33.357  1.00 66.29  ? 77  SER L OG  1 
ATOM   4417 N N   . MET D 3 77  ? 16.412  -1.808  29.930  1.00 57.33  ? 78  MET L N   1 
ATOM   4418 C CA  . MET D 3 77  ? 17.080  -1.301  28.737  1.00 54.17  ? 78  MET L CA  1 
ATOM   4419 C C   . MET D 3 77  ? 18.127  -0.247  29.080  1.00 56.20  ? 78  MET L C   1 
ATOM   4420 O O   . MET D 3 77  ? 17.896  0.641   29.905  1.00 59.10  ? 78  MET L O   1 
ATOM   4421 C CB  . MET D 3 77  ? 16.042  -0.714  27.778  1.00 56.36  ? 78  MET L CB  1 
ATOM   4422 C CG  . MET D 3 77  ? 16.613  0.077   26.609  1.00 53.16  ? 78  MET L CG  1 
ATOM   4423 S SD  . MET D 3 77  ? 17.059  -0.928  25.181  1.00 52.75  ? 78  MET L SD  1 
ATOM   4424 C CE  . MET D 3 77  ? 17.598  0.343   24.038  1.00 43.86  ? 78  MET L CE  1 
ATOM   4425 N N   . GLU D 3 78  ? 19.292  -0.362  28.446  1.00 48.88  ? 79  GLU L N   1 
ATOM   4426 C CA  . GLU D 3 78  ? 20.324  0.659   28.495  1.00 49.22  ? 79  GLU L CA  1 
ATOM   4427 C C   . GLU D 3 78  ? 20.580  1.179   27.086  1.00 51.81  ? 79  GLU L C   1 
ATOM   4428 O O   . GLU D 3 78  ? 20.288  0.508   26.092  1.00 51.79  ? 79  GLU L O   1 
ATOM   4429 C CB  . GLU D 3 78  ? 21.623  0.126   29.119  1.00 54.15  ? 79  GLU L CB  1 
ATOM   4430 C CG  . GLU D 3 78  ? 21.464  -0.349  30.558  1.00 56.19  ? 79  GLU L CG  1 
ATOM   4431 C CD  . GLU D 3 78  ? 22.675  -0.035  31.417  1.00 62.63  ? 79  GLU L CD  1 
ATOM   4432 O OE1 . GLU D 3 78  ? 23.584  0.672   30.934  1.00 55.61  ? 79  GLU L OE1 1 
ATOM   4433 O OE2 . GLU D 3 78  ? 22.716  -0.490  32.579  1.00 52.65  ? 79  GLU L OE2 1 
ATOM   4434 N N   . ALA D 3 79  ? 21.125  2.396   27.012  1.00 48.99  ? 80  ALA L N   1 
ATOM   4435 C CA  . ALA D 3 79  ? 21.341  3.038   25.718  1.00 48.55  ? 80  ALA L CA  1 
ATOM   4436 C C   . ALA D 3 79  ? 22.286  2.227   24.839  1.00 47.95  ? 80  ALA L C   1 
ATOM   4437 O O   . ALA D 3 79  ? 22.098  2.151   23.619  1.00 49.10  ? 80  ALA L O   1 
ATOM   4438 C CB  . ALA D 3 79  ? 21.880  4.455   25.918  1.00 43.17  ? 80  ALA L CB  1 
ATOM   4439 N N   . GLU D 3 80  ? 23.304  1.609   25.439  1.00 45.46  ? 81  GLU L N   1 
ATOM   4440 C CA  . GLU D 3 80  ? 24.271  0.832   24.674  1.00 46.42  ? 81  GLU L CA  1 
ATOM   4441 C C   . GLU D 3 80  ? 23.697  -0.477  24.151  1.00 39.55  ? 81  GLU L C   1 
ATOM   4442 O O   . GLU D 3 80  ? 24.373  -1.163  23.377  1.00 39.47  ? 81  GLU L O   1 
ATOM   4443 C CB  . GLU D 3 80  ? 25.503  0.541   25.531  1.00 44.19  ? 81  GLU L CB  1 
ATOM   4444 C CG  . GLU D 3 80  ? 25.170  -0.034  26.897  1.00 47.20  ? 81  GLU L CG  1 
ATOM   4445 C CD  . GLU D 3 80  ? 26.383  -0.591  27.610  1.00 58.87  ? 81  GLU L CD  1 
ATOM   4446 O OE1 . GLU D 3 80  ? 26.263  -1.666  28.235  1.00 59.61  ? 81  GLU L OE1 1 
ATOM   4447 O OE2 . GLU D 3 80  ? 27.459  0.036   27.536  1.00 56.43  ? 81  GLU L OE2 1 
ATOM   4448 N N   . ASP D 3 81  ? 22.480  -0.842  24.552  1.00 37.22  ? 82  ASP L N   1 
ATOM   4449 C CA  . ASP D 3 81  ? 21.867  -2.077  24.084  1.00 34.51  ? 82  ASP L CA  1 
ATOM   4450 C C   . ASP D 3 81  ? 21.198  -1.932  22.725  1.00 37.81  ? 82  ASP L C   1 
ATOM   4451 O O   . ASP D 3 81  ? 20.778  -2.943  22.152  1.00 35.51  ? 82  ASP L O   1 
ATOM   4452 C CB  . ASP D 3 81  ? 20.844  -2.572  25.109  1.00 39.87  ? 82  ASP L CB  1 
ATOM   4453 C CG  . ASP D 3 81  ? 21.456  -2.801  26.474  1.00 45.79  ? 82  ASP L CG  1 
ATOM   4454 O OD1 . ASP D 3 81  ? 22.679  -3.047  26.543  1.00 43.90  ? 82  ASP L OD1 1 
ATOM   4455 O OD2 . ASP D 3 81  ? 20.716  -2.736  27.479  1.00 46.32  ? 82  ASP L OD2 1 
ATOM   4456 N N   . ALA D 3 82  ? 21.086  -0.713  22.201  1.00 36.33  ? 83  ALA L N   1 
ATOM   4457 C CA  . ALA D 3 82  ? 20.476  -0.506  20.894  1.00 35.85  ? 83  ALA L CA  1 
ATOM   4458 C C   . ALA D 3 82  ? 21.352  -1.125  19.811  1.00 31.47  ? 83  ALA L C   1 
ATOM   4459 O O   . ALA D 3 82  ? 22.486  -0.683  19.594  1.00 43.47  ? 83  ALA L O   1 
ATOM   4460 C CB  . ALA D 3 82  ? 20.274  0.985   20.636  1.00 34.51  ? 83  ALA L CB  1 
ATOM   4461 N N   . ALA D 3 83  ? 20.817  -2.135  19.121  1.00 33.22  ? 84  ALA L N   1 
ATOM   4462 C CA  . ALA D 3 83  ? 21.576  -2.898  18.132  1.00 30.42  ? 84  ALA L CA  1 
ATOM   4463 C C   . ALA D 3 83  ? 20.679  -3.913  17.435  1.00 32.87  ? 84  ALA L C   1 
ATOM   4464 O O   . ALA D 3 83  ? 19.494  -4.019  17.757  1.00 35.50  ? 84  ALA L O   1 
ATOM   4465 C CB  . ALA D 3 83  ? 22.760  -3.616  18.787  1.00 33.11  ? 84  ALA L CB  1 
ATOM   4466 N N   . ALA D 3 84  ? 21.220  -4.665  16.481  1.00 27.68  ? 85  ALA L N   1 
ATOM   4467 C CA  . ALA D 3 84  ? 20.499  -5.784  15.899  1.00 31.62  ? 85  ALA L CA  1 
ATOM   4468 C C   . ALA D 3 84  ? 20.820  -7.050  16.679  1.00 32.07  ? 85  ALA L C   1 
ATOM   4469 O O   . ALA D 3 84  ? 21.954  -7.249  17.125  1.00 31.21  ? 85  ALA L O   1 
ATOM   4470 C CB  . ALA D 3 84  ? 20.866  -5.963  14.426  1.00 26.21  ? 85  ALA L CB  1 
ATOM   4471 N N   . TYR D 3 85  ? 19.813  -7.903  16.848  1.00 35.54  ? 86  TYR L N   1 
ATOM   4472 C CA  . TYR D 3 85  ? 19.968  -9.162  17.567  1.00 32.61  ? 86  TYR L CA  1 
ATOM   4473 C C   . TYR D 3 85  ? 19.481  -10.295 16.678  1.00 31.87  ? 86  TYR L C   1 
ATOM   4474 O O   . TYR D 3 85  ? 18.328  -10.288 16.234  1.00 32.30  ? 86  TYR L O   1 
ATOM   4475 C CB  . TYR D 3 85  ? 19.210  -9.135  18.897  1.00 35.11  ? 86  TYR L CB  1 
ATOM   4476 C CG  . TYR D 3 85  ? 19.803  -8.169  19.900  1.00 37.60  ? 86  TYR L CG  1 
ATOM   4477 C CD1 . TYR D 3 85  ? 20.827  -8.565  20.753  1.00 32.74  ? 86  TYR L CD1 1 
ATOM   4478 C CD2 . TYR D 3 85  ? 19.352  -6.858  19.984  1.00 35.02  ? 86  TYR L CD2 1 
ATOM   4479 C CE1 . TYR D 3 85  ? 21.378  -7.685  21.667  1.00 35.22  ? 86  TYR L CE1 1 
ATOM   4480 C CE2 . TYR D 3 85  ? 19.898  -5.971  20.894  1.00 30.13  ? 86  TYR L CE2 1 
ATOM   4481 C CZ  . TYR D 3 85  ? 20.909  -6.390  21.734  1.00 38.08  ? 86  TYR L CZ  1 
ATOM   4482 O OH  . TYR D 3 85  ? 21.452  -5.509  22.641  1.00 39.43  ? 86  TYR L OH  1 
ATOM   4483 N N   . TYR D 3 86  ? 20.361  -11.257 16.417  1.00 28.62  ? 87  TYR L N   1 
ATOM   4484 C CA  . TYR D 3 86  ? 20.084  -12.380 15.531  1.00 33.07  ? 87  TYR L CA  1 
ATOM   4485 C C   . TYR D 3 86  ? 20.057  -13.677 16.325  1.00 37.40  ? 87  TYR L C   1 
ATOM   4486 O O   . TYR D 3 86  ? 20.962  -13.934 17.127  1.00 38.61  ? 87  TYR L O   1 
ATOM   4487 C CB  . TYR D 3 86  ? 21.140  -12.489 14.427  1.00 31.52  ? 87  TYR L CB  1 
ATOM   4488 C CG  . TYR D 3 86  ? 21.197  -11.325 13.468  1.00 32.43  ? 87  TYR L CG  1 
ATOM   4489 C CD1 . TYR D 3 86  ? 21.888  -10.165 13.788  1.00 30.84  ? 87  TYR L CD1 1 
ATOM   4490 C CD2 . TYR D 3 86  ? 20.577  -11.397 12.228  1.00 35.52  ? 87  TYR L CD2 1 
ATOM   4491 C CE1 . TYR D 3 86  ? 21.948  -9.103  12.906  1.00 31.53  ? 87  TYR L CE1 1 
ATOM   4492 C CE2 . TYR D 3 86  ? 20.631  -10.343 11.341  1.00 33.35  ? 87  TYR L CE2 1 
ATOM   4493 C CZ  . TYR D 3 86  ? 21.318  -9.199  11.683  1.00 34.21  ? 87  TYR L CZ  1 
ATOM   4494 O OH  . TYR D 3 86  ? 21.371  -8.148  10.796  1.00 37.77  ? 87  TYR L OH  1 
ATOM   4495 N N   . CYS D 3 87  ? 19.028  -14.492 16.101  1.00 36.57  ? 88  CYS L N   1 
ATOM   4496 C CA  . CYS D 3 87  ? 19.039  -15.857 16.605  1.00 40.52  ? 88  CYS L CA  1 
ATOM   4497 C C   . CYS D 3 87  ? 19.594  -16.801 15.545  1.00 40.97  ? 88  CYS L C   1 
ATOM   4498 O O   . CYS D 3 87  ? 19.419  -16.593 14.340  1.00 42.16  ? 88  CYS L O   1 
ATOM   4499 C CB  . CYS D 3 87  ? 17.646  -16.310 17.053  1.00 39.32  ? 88  CYS L CB  1 
ATOM   4500 S SG  . CYS D 3 87  ? 16.287  -16.153 15.870  1.00 54.31  ? 88  CYS L SG  1 
ATOM   4501 N N   . GLN D 3 88  ? 20.283  -17.838 16.014  1.00 46.81  ? 89  GLN L N   1 
ATOM   4502 C CA  . GLN D 3 88  ? 21.028  -18.746 15.157  1.00 40.48  ? 89  GLN L CA  1 
ATOM   4503 C C   . GLN D 3 88  ? 20.974  -20.154 15.730  1.00 46.66  ? 89  GLN L C   1 
ATOM   4504 O O   . GLN D 3 88  ? 21.088  -20.345 16.944  1.00 44.91  ? 89  GLN L O   1 
ATOM   4505 C CB  . GLN D 3 88  ? 22.483  -18.281 15.006  1.00 32.33  ? 89  GLN L CB  1 
ATOM   4506 C CG  . GLN D 3 88  ? 23.403  -19.258 14.288  1.00 40.22  ? 89  GLN L CG  1 
ATOM   4507 C CD  . GLN D 3 88  ? 24.124  -20.195 15.239  1.00 42.57  ? 89  GLN L CD  1 
ATOM   4508 O OE1 . GLN D 3 88  ? 24.657  -19.769 16.262  1.00 41.88  ? 89  GLN L OE1 1 
ATOM   4509 N NE2 . GLN D 3 88  ? 24.145  -21.479 14.902  1.00 40.76  ? 89  GLN L NE2 1 
ATOM   4510 N N   . GLN D 3 89  ? 20.792  -21.132 14.845  1.00 49.47  ? 90  GLN L N   1 
ATOM   4511 C CA  . GLN D 3 89  ? 20.699  -22.534 15.222  1.00 48.65  ? 90  GLN L CA  1 
ATOM   4512 C C   . GLN D 3 89  ? 21.661  -23.349 14.369  1.00 48.78  ? 90  GLN L C   1 
ATOM   4513 O O   . GLN D 3 89  ? 22.017  -22.957 13.252  1.00 44.05  ? 90  GLN L O   1 
ATOM   4514 C CB  . GLN D 3 89  ? 19.262  -23.070 15.078  1.00 46.52  ? 90  GLN L CB  1 
ATOM   4515 C CG  . GLN D 3 89  ? 18.775  -23.224 13.645  1.00 50.62  ? 90  GLN L CG  1 
ATOM   4516 C CD  . GLN D 3 89  ? 19.065  -24.600 13.074  1.00 57.01  ? 90  GLN L CD  1 
ATOM   4517 O OE1 . GLN D 3 89  ? 19.346  -25.544 13.812  1.00 58.76  ? 90  GLN L OE1 1 
ATOM   4518 N NE2 . GLN D 3 89  ? 19.000  -24.717 11.754  1.00 57.79  ? 90  GLN L NE2 1 
ATOM   4519 N N   . TRP D 3 90  ? 22.090  -24.486 14.914  1.00 48.97  ? 91  TRP L N   1 
ATOM   4520 C CA  . TRP D 3 90  ? 22.974  -25.417 14.227  1.00 49.07  ? 91  TRP L CA  1 
ATOM   4521 C C   . TRP D 3 90  ? 22.318  -26.786 14.140  1.00 51.52  ? 91  TRP L C   1 
ATOM   4522 O O   . TRP D 3 90  ? 21.910  -27.347 15.163  1.00 51.79  ? 91  TRP L O   1 
ATOM   4523 C CB  . TRP D 3 90  ? 24.319  -25.529 14.952  1.00 48.88  ? 91  TRP L CB  1 
ATOM   4524 C CG  . TRP D 3 90  ? 25.124  -26.721 14.538  1.00 50.61  ? 91  TRP L CG  1 
ATOM   4525 C CD1 . TRP D 3 90  ? 25.323  -27.865 15.254  1.00 54.05  ? 91  TRP L CD1 1 
ATOM   4526 C CD2 . TRP D 3 90  ? 25.835  -26.891 13.307  1.00 49.32  ? 91  TRP L CD2 1 
ATOM   4527 N NE1 . TRP D 3 90  ? 26.117  -28.735 14.548  1.00 51.99  ? 91  TRP L NE1 1 
ATOM   4528 C CE2 . TRP D 3 90  ? 26.444  -28.160 13.348  1.00 53.76  ? 91  TRP L CE2 1 
ATOM   4529 C CE3 . TRP D 3 90  ? 26.017  -26.091 12.175  1.00 52.79  ? 91  TRP L CE3 1 
ATOM   4530 C CZ2 . TRP D 3 90  ? 27.222  -28.648 12.300  1.00 47.60  ? 91  TRP L CZ2 1 
ATOM   4531 C CZ3 . TRP D 3 90  ? 26.785  -26.579 11.135  1.00 50.99  ? 91  TRP L CZ3 1 
ATOM   4532 C CH2 . TRP D 3 90  ? 27.381  -27.843 11.206  1.00 45.62  ? 91  TRP L CH2 1 
ATOM   4533 N N   . SER D 3 91  ? 22.216  -27.321 12.924  1.00 51.32  ? 92  SER L N   1 
ATOM   4534 C CA  . SER D 3 91  ? 21.703  -28.662 12.689  1.00 50.65  ? 92  SER L CA  1 
ATOM   4535 C C   . SER D 3 91  ? 22.829  -29.550 12.177  1.00 52.25  ? 92  SER L C   1 
ATOM   4536 O O   . SER D 3 91  ? 23.626  -29.132 11.329  1.00 47.62  ? 92  SER L O   1 
ATOM   4537 C CB  . SER D 3 91  ? 20.548  -28.643 11.686  1.00 51.06  ? 92  SER L CB  1 
ATOM   4538 O OG  . SER D 3 91  ? 19.506  -27.787 12.120  1.00 49.95  ? 92  SER L OG  1 
ATOM   4539 N N   . SER D 3 92  ? 22.883  -30.778 12.691  1.00 56.24  ? 93  SER L N   1 
ATOM   4540 C CA  . SER D 3 92  ? 23.937  -31.723 12.340  1.00 59.48  ? 93  SER L CA  1 
ATOM   4541 C C   . SER D 3 92  ? 23.488  -32.804 11.369  1.00 63.39  ? 93  SER L C   1 
ATOM   4542 O O   . SER D 3 92  ? 24.299  -33.250 10.550  1.00 57.23  ? 93  SER L O   1 
ATOM   4543 C CB  . SER D 3 92  ? 24.492  -32.391 13.603  1.00 59.04  ? 93  SER L CB  1 
ATOM   4544 O OG  . SER D 3 92  ? 23.447  -32.954 14.377  1.00 59.15  ? 93  SER L OG  1 
ATOM   4545 N N   . ASP D 3 93  ? 22.227  -33.243 11.439  1.00 69.12  ? 94  ASP L N   1 
ATOM   4546 C CA  . ASP D 3 93  ? 21.778  -34.340 10.583  1.00 69.14  ? 94  ASP L CA  1 
ATOM   4547 C C   . ASP D 3 93  ? 21.964  -34.023 9.098   1.00 73.92  ? 94  ASP L C   1 
ATOM   4548 O O   . ASP D 3 93  ? 22.604  -34.829 8.401   1.00 81.24  ? 94  ASP L O   1 
ATOM   4549 C CB  . ASP D 3 93  ? 20.336  -34.714 10.950  1.00 78.08  ? 94  ASP L CB  1 
ATOM   4550 C CG  . ASP D 3 93  ? 19.766  -35.791 10.050  1.00 82.23  ? 94  ASP L CG  1 
ATOM   4551 O OD1 . ASP D 3 93  ? 20.206  -36.956 10.150  1.00 83.32  ? 94  ASP L OD1 1 
ATOM   4552 O OD2 . ASP D 3 93  ? 18.885  -35.467 9.227   1.00 81.71  ? 94  ASP L OD2 1 
ATOM   4553 N N   . PRO D 3 94  ? 21.439  -32.923 8.546   1.00 75.16  ? 95  PRO L N   1 
ATOM   4554 C CA  . PRO D 3 94  ? 22.127  -32.264 7.426   1.00 58.32  ? 95  PRO L CA  1 
ATOM   4555 C C   . PRO D 3 94  ? 22.863  -31.027 7.917   1.00 60.12  ? 95  PRO L C   1 
ATOM   4556 O O   . PRO D 3 94  ? 22.238  -30.014 8.273   1.00 65.68  ? 95  PRO L O   1 
ATOM   4557 C CB  . PRO D 3 94  ? 20.985  -31.873 6.477   1.00 61.42  ? 95  PRO L CB  1 
ATOM   4558 C CG  . PRO D 3 94  ? 19.797  -31.780 7.310   1.00 65.85  ? 95  PRO L CG  1 
ATOM   4559 C CD  . PRO D 3 94  ? 20.057  -32.427 8.650   1.00 70.91  ? 95  PRO L CD  1 
ATOM   4560 N N   . PRO D 3 95  A 24.194  -31.054 7.935   1.00 54.86  ? 95  PRO L N   1 
ATOM   4561 C CA  . PRO D 3 95  A 24.943  -29.940 8.541   1.00 54.01  ? 95  PRO L CA  1 
ATOM   4562 C C   . PRO D 3 95  A 24.605  -28.567 7.968   1.00 52.43  ? 95  PRO L C   1 
ATOM   4563 O O   . PRO D 3 95  A 24.939  -28.250 6.820   1.00 47.14  ? 95  PRO L O   1 
ATOM   4564 C CB  . PRO D 3 95  A 26.404  -30.312 8.262   1.00 49.18  ? 95  PRO L CB  1 
ATOM   4565 C CG  . PRO D 3 95  A 26.351  -31.270 7.117   1.00 51.12  ? 95  PRO L CG  1 
ATOM   4566 C CD  . PRO D 3 95  A 25.079  -32.035 7.285   1.00 53.54  ? 95  PRO L CD  1 
ATOM   4567 N N   . MET D 3 96  B 23.950  -27.736 8.779   1.00 51.71  ? 95  MET L N   1 
ATOM   4568 C CA  . MET D 3 96  B 23.501  -26.423 8.331   1.00 52.05  ? 95  MET L CA  1 
ATOM   4569 C C   . MET D 3 96  B 23.464  -25.455 9.505   1.00 51.98  ? 95  MET L C   1 
ATOM   4570 O O   . MET D 3 96  B 22.933  -25.777 10.572  1.00 47.30  ? 95  MET L O   1 
ATOM   4571 C CB  . MET D 3 96  B 22.120  -26.509 7.672   1.00 49.99  ? 95  MET L CB  1 
ATOM   4572 C CG  . MET D 3 96  B 22.133  -26.234 6.179   1.00 59.22  ? 95  MET L CG  1 
ATOM   4573 S SD  . MET D 3 96  B 22.615  -24.541 5.786   1.00 60.40  ? 95  MET L SD  1 
ATOM   4574 C CE  . MET D 3 96  B 21.195  -23.631 6.387   1.00 54.17  ? 95  MET L CE  1 
ATOM   4575 N N   . LEU D 3 97  ? 24.026  -24.269 9.297   1.00 47.66  ? 96  LEU L N   1 
ATOM   4576 C CA  . LEU D 3 97  ? 24.041  -23.195 10.282  1.00 42.21  ? 96  LEU L CA  1 
ATOM   4577 C C   . LEU D 3 97  ? 23.106  -22.097 9.788   1.00 44.77  ? 96  LEU L C   1 
ATOM   4578 O O   . LEU D 3 97  ? 23.358  -21.497 8.737   1.00 45.32  ? 96  LEU L O   1 
ATOM   4579 C CB  . LEU D 3 97  ? 25.466  -22.673 10.475  1.00 37.44  ? 96  LEU L CB  1 
ATOM   4580 C CG  . LEU D 3 97  ? 25.842  -21.839 11.700  1.00 44.73  ? 96  LEU L CG  1 
ATOM   4581 C CD1 . LEU D 3 97  ? 27.347  -21.886 11.912  1.00 40.30  ? 96  LEU L CD1 1 
ATOM   4582 C CD2 . LEU D 3 97  ? 25.386  -20.405 11.547  1.00 45.64  ? 96  LEU L CD2 1 
ATOM   4583 N N   . THR D 3 98  ? 22.032  -21.837 10.534  1.00 46.50  ? 97  THR L N   1 
ATOM   4584 C CA  . THR D 3 98  ? 20.970  -20.951 10.071  1.00 46.09  ? 97  THR L CA  1 
ATOM   4585 C C   . THR D 3 98  ? 20.818  -19.759 11.004  1.00 43.95  ? 97  THR L C   1 
ATOM   4586 O O   . THR D 3 98  ? 20.801  -19.918 12.229  1.00 45.44  ? 97  THR L O   1 
ATOM   4587 C CB  . THR D 3 98  ? 19.635  -21.697 9.972   1.00 47.34  ? 97  THR L CB  1 
ATOM   4588 O OG1 . THR D 3 98  ? 19.829  -22.939 9.286   1.00 60.12  ? 97  THR L OG1 1 
ATOM   4589 C CG2 . THR D 3 98  ? 18.613  -20.860 9.221   1.00 47.09  ? 97  THR L CG2 1 
ATOM   4590 N N   . PHE D 3 99  ? 20.707  -18.571 10.419  1.00 42.72  ? 98  PHE L N   1 
ATOM   4591 C CA  . PHE D 3 99  ? 20.432  -17.340 11.144  1.00 42.69  ? 98  PHE L CA  1 
ATOM   4592 C C   . PHE D 3 99  ? 18.978  -16.922 10.960  1.00 41.10  ? 98  PHE L C   1 
ATOM   4593 O O   . PHE D 3 99  ? 18.287  -17.366 10.040  1.00 44.56  ? 98  PHE L O   1 
ATOM   4594 C CB  . PHE D 3 99  ? 21.344  -16.204 10.671  1.00 40.64  ? 98  PHE L CB  1 
ATOM   4595 C CG  . PHE D 3 99  ? 22.786  -16.386 11.034  1.00 36.91  ? 98  PHE L CG  1 
ATOM   4596 C CD1 . PHE D 3 99  ? 23.270  -15.927 12.247  1.00 33.23  ? 98  PHE L CD1 1 
ATOM   4597 C CD2 . PHE D 3 99  ? 23.663  -16.996 10.154  1.00 33.91  ? 98  PHE L CD2 1 
ATOM   4598 C CE1 . PHE D 3 99  ? 24.599  -16.086 12.583  1.00 37.00  ? 98  PHE L CE1 1 
ATOM   4599 C CE2 . PHE D 3 99  ? 24.994  -17.155 10.482  1.00 41.23  ? 98  PHE L CE2 1 
ATOM   4600 C CZ  . PHE D 3 99  ? 25.463  -16.702 11.699  1.00 36.39  ? 98  PHE L CZ  1 
ATOM   4601 N N   . GLY D 3 100 ? 18.523  -16.049 11.858  1.00 39.38  ? 99  GLY L N   1 
ATOM   4602 C CA  . GLY D 3 100 ? 17.255  -15.378 11.677  1.00 42.98  ? 99  GLY L CA  1 
ATOM   4603 C C   . GLY D 3 100 ? 17.427  -14.019 11.018  1.00 39.67  ? 99  GLY L C   1 
ATOM   4604 O O   . GLY D 3 100 ? 18.532  -13.496 10.894  1.00 40.53  ? 99  GLY L O   1 
ATOM   4605 N N   . ALA D 3 101 ? 16.299  -13.443 10.596  1.00 38.45  ? 100 ALA L N   1 
ATOM   4606 C CA  . ALA D 3 101 ? 16.324  -12.141 9.939   1.00 39.32  ? 100 ALA L CA  1 
ATOM   4607 C C   . ALA D 3 101 ? 16.774  -11.018 10.864  1.00 41.15  ? 100 ALA L C   1 
ATOM   4608 O O   . ALA D 3 101 ? 17.065  -9.920  10.378  1.00 41.84  ? 100 ALA L O   1 
ATOM   4609 C CB  . ALA D 3 101 ? 14.944  -11.814 9.365   1.00 40.03  ? 100 ALA L CB  1 
ATOM   4610 N N   . GLY D 3 102 ? 16.849  -11.264 12.169  1.00 40.16  ? 101 GLY L N   1 
ATOM   4611 C CA  . GLY D 3 102 ? 17.287  -10.252 13.108  1.00 34.70  ? 101 GLY L CA  1 
ATOM   4612 C C   . GLY D 3 102 ? 16.191  -9.309  13.552  1.00 35.60  ? 101 GLY L C   1 
ATOM   4613 O O   . GLY D 3 102 ? 15.228  -9.063  12.818  1.00 39.21  ? 101 GLY L O   1 
ATOM   4614 N N   . THR D 3 103 ? 16.326  -8.781  14.765  1.00 35.93  ? 102 THR L N   1 
ATOM   4615 C CA  . THR D 3 103 ? 15.431  -7.764  15.296  1.00 36.28  ? 102 THR L CA  1 
ATOM   4616 C C   . THR D 3 103 ? 16.251  -6.530  15.636  1.00 38.38  ? 102 THR L C   1 
ATOM   4617 O O   . THR D 3 103 ? 17.255  -6.628  16.348  1.00 34.01  ? 102 THR L O   1 
ATOM   4618 C CB  . THR D 3 103 ? 14.692  -8.267  16.541  1.00 38.13  ? 102 THR L CB  1 
ATOM   4619 O OG1 . THR D 3 103 ? 13.695  -9.224  16.160  1.00 39.29  ? 102 THR L OG1 1 
ATOM   4620 C CG2 . THR D 3 103 ? 14.034  -7.109  17.280  1.00 39.03  ? 102 THR L CG2 1 
ATOM   4621 N N   . LYS D 3 104 ? 15.837  -5.379  15.115  1.00 35.01  ? 103 LYS L N   1 
ATOM   4622 C CA  . LYS D 3 104 ? 16.496  -4.117  15.421  1.00 34.46  ? 103 LYS L CA  1 
ATOM   4623 C C   . LYS D 3 104 ? 15.888  -3.527  16.688  1.00 39.35  ? 103 LYS L C   1 
ATOM   4624 O O   . LYS D 3 104 ? 14.676  -3.291  16.751  1.00 42.35  ? 103 LYS L O   1 
ATOM   4625 C CB  . LYS D 3 104 ? 16.376  -3.138  14.254  1.00 32.22  ? 103 LYS L CB  1 
ATOM   4626 C CG  . LYS D 3 104 ? 17.014  -1.788  14.537  1.00 37.82  ? 103 LYS L CG  1 
ATOM   4627 C CD  . LYS D 3 104 ? 16.897  -0.842  13.352  1.00 35.31  ? 103 LYS L CD  1 
ATOM   4628 C CE  . LYS D 3 104 ? 17.555  0.496   13.659  1.00 40.76  ? 103 LYS L CE  1 
ATOM   4629 N NZ  . LYS D 3 104 ? 17.459  1.448   12.522  1.00 43.51  ? 103 LYS L NZ  1 
ATOM   4630 N N   . LEU D 3 105 ? 16.728  -3.295  17.694  1.00 33.93  ? 104 LEU L N   1 
ATOM   4631 C CA  . LEU D 3 105 ? 16.345  -2.662  18.949  1.00 32.42  ? 104 LEU L CA  1 
ATOM   4632 C C   . LEU D 3 105 ? 16.877  -1.235  18.929  1.00 35.69  ? 104 LEU L C   1 
ATOM   4633 O O   . LEU D 3 105 ? 18.094  -1.019  18.998  1.00 41.89  ? 104 LEU L O   1 
ATOM   4634 C CB  . LEU D 3 105 ? 16.892  -3.444  20.142  1.00 36.04  ? 104 LEU L CB  1 
ATOM   4635 C CG  . LEU D 3 105 ? 16.678  -2.835  21.528  1.00 37.00  ? 104 LEU L CG  1 
ATOM   4636 C CD1 . LEU D 3 105 ? 15.208  -2.558  21.782  1.00 35.14  ? 104 LEU L CD1 1 
ATOM   4637 C CD2 . LEU D 3 105 ? 17.252  -3.744  22.603  1.00 35.29  ? 104 LEU L CD2 1 
ATOM   4638 N N   . GLU D 3 106 ? 15.966  -0.272  18.830  1.00 33.42  ? 105 GLU L N   1 
ATOM   4639 C CA  . GLU D 3 106 ? 16.292  1.138   18.689  1.00 34.52  ? 105 GLU L CA  1 
ATOM   4640 C C   . GLU D 3 106 ? 15.918  1.899   19.954  1.00 29.36  ? 105 GLU L C   1 
ATOM   4641 O O   . GLU D 3 106 ? 15.130  1.430   20.781  1.00 40.78  ? 105 GLU L O   1 
ATOM   4642 C CB  . GLU D 3 106 ? 15.559  1.752   17.490  1.00 37.19  ? 105 GLU L CB  1 
ATOM   4643 C CG  . GLU D 3 106 ? 14.071  1.966   17.738  1.00 39.57  ? 105 GLU L CG  1 
ATOM   4644 C CD  . GLU D 3 106 ? 13.401  2.773   16.643  1.00 40.94  ? 105 GLU L CD  1 
ATOM   4645 O OE1 . GLU D 3 106 ? 14.006  2.929   15.562  1.00 39.36  ? 105 GLU L OE1 1 
ATOM   4646 O OE2 . GLU D 3 106 ? 12.270  3.253   16.866  1.00 36.13  ? 105 GLU L OE2 1 
ATOM   4647 N N   . LEU D 3 107 ? 16.496  3.090   20.091  1.00 32.60  ? 106 LEU L N   1 
ATOM   4648 C CA  . LEU D 3 107 ? 16.202  3.967   21.217  1.00 39.79  ? 106 LEU L CA  1 
ATOM   4649 C C   . LEU D 3 107 ? 14.930  4.759   20.946  1.00 36.92  ? 106 LEU L C   1 
ATOM   4650 O O   . LEU D 3 107 ? 14.837  5.468   19.938  1.00 36.44  ? 106 LEU L O   1 
ATOM   4651 C CB  . LEU D 3 107 ? 17.373  4.913   21.470  1.00 36.35  ? 106 LEU L CB  1 
ATOM   4652 C CG  . LEU D 3 107 ? 18.518  4.393   22.335  1.00 46.10  ? 106 LEU L CG  1 
ATOM   4653 C CD1 . LEU D 3 107 ? 19.690  5.356   22.312  1.00 48.84  ? 106 LEU L CD1 1 
ATOM   4654 C CD2 . LEU D 3 107 ? 17.997  4.241   23.759  1.00 48.65  ? 106 LEU L CD2 1 
ATOM   4655 N N   . LYS D 3 108 ? 13.957  4.644   21.847  1.00 43.46  ? 107 LYS L N   1 
ATOM   4656 C CA  . LYS D 3 108 ? 12.723  5.404   21.727  1.00 36.02  ? 107 LYS L CA  1 
ATOM   4657 C C   . LYS D 3 108 ? 12.900  6.801   22.307  1.00 34.92  ? 107 LYS L C   1 
ATOM   4658 O O   . LYS D 3 108 ? 13.542  6.983   23.346  1.00 40.06  ? 107 LYS L O   1 
ATOM   4659 C CB  . LYS D 3 108 ? 11.576  4.687   22.440  1.00 43.21  ? 107 LYS L CB  1 
ATOM   4660 C CG  . LYS D 3 108 ? 10.265  5.462   22.410  1.00 46.66  ? 107 LYS L CG  1 
ATOM   4661 C CD  . LYS D 3 108 ? 9.173   4.794   23.227  1.00 45.12  ? 107 LYS L CD  1 
ATOM   4662 C CE  . LYS D 3 108 ? 8.617   3.567   22.527  1.00 50.09  ? 107 LYS L CE  1 
ATOM   4663 N NZ  . LYS D 3 108 ? 7.482   2.988   23.291  1.00 59.43  ? 107 LYS L NZ  1 
ATOM   4664 N N   . ARG D 3 109 ? 12.322  7.789   21.629  1.00 31.36  ? 108 ARG L N   1 
ATOM   4665 C CA  . ARG D 3 109 ? 12.340  9.168   22.092  1.00 33.44  ? 108 ARG L CA  1 
ATOM   4666 C C   . ARG D 3 109 ? 10.963  9.769   21.838  1.00 35.30  ? 108 ARG L C   1 
ATOM   4667 O O   . ARG D 3 109 ? 10.012  9.070   21.474  1.00 29.69  ? 108 ARG L O   1 
ATOM   4668 C CB  . ARG D 3 109 ? 13.449  9.971   21.403  1.00 26.63  ? 108 ARG L CB  1 
ATOM   4669 C CG  . ARG D 3 109 ? 13.324  10.013  19.895  1.00 29.79  ? 108 ARG L CG  1 
ATOM   4670 C CD  . ARG D 3 109 ? 13.934  11.281  19.336  1.00 33.25  ? 108 ARG L CD  1 
ATOM   4671 N NE  . ARG D 3 109 ? 13.137  12.461  19.650  1.00 29.96  ? 108 ARG L NE  1 
ATOM   4672 C CZ  . ARG D 3 109 ? 13.603  13.702  19.647  1.00 33.08  ? 108 ARG L CZ  1 
ATOM   4673 N NH1 . ARG D 3 109 ? 14.872  13.964  19.382  1.00 34.73  ? 108 ARG L NH1 1 
ATOM   4674 N NH2 . ARG D 3 109 ? 12.774  14.706  19.919  1.00 32.92  ? 108 ARG L NH2 1 
ATOM   4675 N N   . THR D 3 110 ? 10.857  11.078  22.036  1.00 32.82  ? 109 THR L N   1 
ATOM   4676 C CA  . THR D 3 110 ? 9.617   11.790  21.775  1.00 32.04  ? 109 THR L CA  1 
ATOM   4677 C C   . THR D 3 110 ? 9.408   11.974  20.274  1.00 36.89  ? 109 THR L C   1 
ATOM   4678 O O   . THR D 3 110 ? 10.342  11.895  19.472  1.00 30.84  ? 109 THR L O   1 
ATOM   4679 C CB  . THR D 3 110 ? 9.620   13.153  22.470  1.00 33.17  ? 109 THR L CB  1 
ATOM   4680 O OG1 . THR D 3 110 ? 10.754  13.911  22.029  1.00 36.17  ? 109 THR L OG1 1 
ATOM   4681 C CG2 . THR D 3 110 ? 9.687   12.979  23.982  1.00 33.48  ? 109 THR L CG2 1 
ATOM   4682 N N   . VAL D 3 111 ? 8.151   12.216  19.900  1.00 33.65  ? 110 VAL L N   1 
ATOM   4683 C CA  . VAL D 3 111 ? 7.802   12.389  18.496  1.00 32.07  ? 110 VAL L CA  1 
ATOM   4684 C C   . VAL D 3 111 ? 8.390   13.695  17.983  1.00 35.49  ? 110 VAL L C   1 
ATOM   4685 O O   . VAL D 3 111 ? 8.290   14.742  18.636  1.00 33.08  ? 110 VAL L O   1 
ATOM   4686 C CB  . VAL D 3 111 ? 6.277   12.359  18.310  1.00 33.02  ? 110 VAL L CB  1 
ATOM   4687 C CG1 . VAL D 3 111 ? 5.910   12.662  16.863  1.00 25.12  ? 110 VAL L CG1 1 
ATOM   4688 C CG2 . VAL D 3 111 ? 5.719   11.016  18.731  1.00 28.75  ? 110 VAL L CG2 1 
ATOM   4689 N N   . ALA D 3 112 ? 9.007   13.639  16.805  1.00 30.85  ? 111 ALA L N   1 
ATOM   4690 C CA  . ALA D 3 112 ? 9.532   14.824  16.140  1.00 29.13  ? 111 ALA L CA  1 
ATOM   4691 C C   . ALA D 3 112 ? 9.145   14.751  14.673  1.00 33.23  ? 111 ALA L C   1 
ATOM   4692 O O   . ALA D 3 112 ? 9.565   13.831  13.965  1.00 29.00  ? 111 ALA L O   1 
ATOM   4693 C CB  . ALA D 3 112 ? 11.052  14.926  16.295  1.00 29.14  ? 111 ALA L CB  1 
ATOM   4694 N N   . ALA D 3 113 ? 8.337   15.706  14.223  1.00 31.75  ? 112 ALA L N   1 
ATOM   4695 C CA  . ALA D 3 113 ? 7.976   15.755  12.819  1.00 31.06  ? 112 ALA L CA  1 
ATOM   4696 C C   . ALA D 3 113 ? 9.192   16.148  11.982  1.00 32.27  ? 112 ALA L C   1 
ATOM   4697 O O   . ALA D 3 113 ? 10.030  16.938  12.423  1.00 32.27  ? 112 ALA L O   1 
ATOM   4698 C CB  . ALA D 3 113 ? 6.839   16.747  12.591  1.00 30.02  ? 112 ALA L CB  1 
ATOM   4699 N N   . PRO D 3 114 ? 9.316   15.606  10.773  1.00 34.90  ? 113 PRO L N   1 
ATOM   4700 C CA  . PRO D 3 114 ? 10.480  15.929  9.945   1.00 37.28  ? 113 PRO L CA  1 
ATOM   4701 C C   . PRO D 3 114 ? 10.425  17.360  9.441   1.00 37.37  ? 113 PRO L C   1 
ATOM   4702 O O   . PRO D 3 114 ? 9.352   17.932  9.234   1.00 37.83  ? 113 PRO L O   1 
ATOM   4703 C CB  . PRO D 3 114 ? 10.378  14.930  8.786   1.00 29.93  ? 113 PRO L CB  1 
ATOM   4704 C CG  . PRO D 3 114 ? 8.921   14.626  8.692   1.00 32.84  ? 113 PRO L CG  1 
ATOM   4705 C CD  . PRO D 3 114 ? 8.404   14.660  10.103  1.00 34.50  ? 113 PRO L CD  1 
ATOM   4706 N N   . SER D 3 115 ? 11.606  17.943  9.252   1.00 36.38  ? 114 SER L N   1 
ATOM   4707 C CA  . SER D 3 115 ? 11.721  19.193  8.513   1.00 35.57  ? 114 SER L CA  1 
ATOM   4708 C C   . SER D 3 115 ? 11.948  18.867  7.043   1.00 36.19  ? 114 SER L C   1 
ATOM   4709 O O   . SER D 3 115 ? 12.876  18.128  6.707   1.00 38.71  ? 114 SER L O   1 
ATOM   4710 C CB  . SER D 3 115 ? 12.860  20.050  9.064   1.00 37.59  ? 114 SER L CB  1 
ATOM   4711 O OG  . SER D 3 115 ? 12.554  20.523  10.365  1.00 45.24  ? 114 SER L OG  1 
ATOM   4712 N N   . VAL D 3 116 ? 11.102  19.406  6.171   1.00 39.79  ? 115 VAL L N   1 
ATOM   4713 C CA  . VAL D 3 116 ? 11.111  19.043  4.758   1.00 33.88  ? 115 VAL L CA  1 
ATOM   4714 C C   . VAL D 3 116 ? 11.773  20.157  3.961   1.00 36.97  ? 115 VAL L C   1 
ATOM   4715 O O   . VAL D 3 116 ? 11.420  21.334  4.105   1.00 37.46  ? 115 VAL L O   1 
ATOM   4716 C CB  . VAL D 3 116 ? 9.687   18.768  4.243   1.00 32.02  ? 115 VAL L CB  1 
ATOM   4717 C CG1 . VAL D 3 116 ? 9.735   18.168  2.845   1.00 30.84  ? 115 VAL L CG1 1 
ATOM   4718 C CG2 . VAL D 3 116 ? 8.948   17.846  5.199   1.00 34.94  ? 115 VAL L CG2 1 
ATOM   4719 N N   . PHE D 3 117 ? 12.734  19.783  3.121   1.00 31.95  ? 116 PHE L N   1 
ATOM   4720 C CA  . PHE D 3 117 ? 13.408  20.711  2.224   1.00 37.32  ? 116 PHE L CA  1 
ATOM   4721 C C   . PHE D 3 117 ? 13.485  20.088  0.838   1.00 36.30  ? 116 PHE L C   1 
ATOM   4722 O O   . PHE D 3 117 ? 13.515  18.864  0.698   1.00 36.83  ? 116 PHE L O   1 
ATOM   4723 C CB  . PHE D 3 117 ? 14.823  21.052  2.720   1.00 39.56  ? 116 PHE L CB  1 
ATOM   4724 C CG  . PHE D 3 117 ? 14.879  21.477  4.162   1.00 37.50  ? 116 PHE L CG  1 
ATOM   4725 C CD1 . PHE D 3 117 ? 15.028  20.537  5.169   1.00 37.17  ? 116 PHE L CD1 1 
ATOM   4726 C CD2 . PHE D 3 117 ? 14.783  22.813  4.512   1.00 39.02  ? 116 PHE L CD2 1 
ATOM   4727 C CE1 . PHE D 3 117 ? 15.083  20.922  6.495   1.00 37.00  ? 116 PHE L CE1 1 
ATOM   4728 C CE2 . PHE D 3 117 ? 14.836  23.205  5.837   1.00 40.07  ? 116 PHE L CE2 1 
ATOM   4729 C CZ  . PHE D 3 117 ? 14.985  22.257  6.830   1.00 40.95  ? 116 PHE L CZ  1 
ATOM   4730 N N   . ILE D 3 118 ? 13.496  20.929  -0.194  1.00 37.37  ? 117 ILE L N   1 
ATOM   4731 C CA  . ILE D 3 118 ? 13.619  20.450  -1.565  1.00 34.58  ? 117 ILE L CA  1 
ATOM   4732 C C   . ILE D 3 118 ? 14.709  21.241  -2.277  1.00 35.38  ? 117 ILE L C   1 
ATOM   4733 O O   . ILE D 3 118 ? 14.885  22.441  -2.036  1.00 35.08  ? 117 ILE L O   1 
ATOM   4734 C CB  . ILE D 3 118 ? 12.277  20.524  -2.330  1.00 42.56  ? 117 ILE L CB  1 
ATOM   4735 C CG1 . ILE D 3 118 ? 12.359  19.718  -3.629  1.00 40.82  ? 117 ILE L CG1 1 
ATOM   4736 C CG2 . ILE D 3 118 ? 11.877  21.966  -2.607  1.00 41.10  ? 117 ILE L CG2 1 
ATOM   4737 C CD1 . ILE D 3 118 ? 11.034  19.555  -4.337  1.00 42.92  ? 117 ILE L CD1 1 
ATOM   4738 N N   . PHE D 3 119 ? 15.457  20.552  -3.137  1.00 37.06  ? 118 PHE L N   1 
ATOM   4739 C CA  . PHE D 3 119 ? 16.563  21.135  -3.886  1.00 36.45  ? 118 PHE L CA  1 
ATOM   4740 C C   . PHE D 3 119 ? 16.363  20.794  -5.354  1.00 38.84  ? 118 PHE L C   1 
ATOM   4741 O O   . PHE D 3 119 ? 16.290  19.594  -5.708  1.00 33.30  ? 118 PHE L O   1 
ATOM   4742 C CB  . PHE D 3 119 ? 17.917  20.619  -3.393  1.00 35.84  ? 118 PHE L CB  1 
ATOM   4743 C CG  . PHE D 3 119 ? 18.157  20.839  -1.928  1.00 38.40  ? 118 PHE L CG  1 
ATOM   4744 C CD1 . PHE D 3 119 ? 18.575  22.073  -1.460  1.00 34.14  ? 118 PHE L CD1 1 
ATOM   4745 C CD2 . PHE D 3 119 ? 17.978  19.809  -1.021  1.00 33.91  ? 118 PHE L CD2 1 
ATOM   4746 C CE1 . PHE D 3 119 ? 18.802  22.279  -0.113  1.00 39.37  ? 118 PHE L CE1 1 
ATOM   4747 C CE2 . PHE D 3 119 ? 18.204  20.007  0.328   1.00 39.54  ? 118 PHE L CE2 1 
ATOM   4748 C CZ  . PHE D 3 119 ? 18.615  21.245  0.782   1.00 38.24  ? 118 PHE L CZ  1 
ATOM   4749 N N   . PRO D 3 120 ? 16.262  21.787  -6.233  1.00 43.14  ? 119 PRO L N   1 
ATOM   4750 C CA  . PRO D 3 120 ? 16.190  21.520  -7.670  1.00 37.10  ? 119 PRO L CA  1 
ATOM   4751 C C   . PRO D 3 120 ? 17.562  21.169  -8.214  1.00 43.10  ? 119 PRO L C   1 
ATOM   4752 O O   . PRO D 3 120 ? 18.578  21.377  -7.532  1.00 40.45  ? 119 PRO L O   1 
ATOM   4753 C CB  . PRO D 3 120 ? 15.683  22.851  -8.255  1.00 47.58  ? 119 PRO L CB  1 
ATOM   4754 C CG  . PRO D 3 120 ? 15.289  23.701  -7.069  1.00 45.16  ? 119 PRO L CG  1 
ATOM   4755 C CD  . PRO D 3 120 ? 16.119  23.219  -5.933  1.00 48.84  ? 119 PRO L CD  1 
ATOM   4756 N N   . PRO D 3 121 ? 17.641  20.624  -9.426  1.00 39.09  ? 120 PRO L N   1 
ATOM   4757 C CA  . PRO D 3 121 ? 18.954  20.358  -10.019 1.00 39.23  ? 120 PRO L CA  1 
ATOM   4758 C C   . PRO D 3 121 ? 19.704  21.650  -10.296 1.00 45.24  ? 120 PRO L C   1 
ATOM   4759 O O   . PRO D 3 121 ? 19.112  22.711  -10.510 1.00 43.77  ? 120 PRO L O   1 
ATOM   4760 C CB  . PRO D 3 121 ? 18.618  19.620  -11.321 1.00 38.85  ? 120 PRO L CB  1 
ATOM   4761 C CG  . PRO D 3 121 ? 17.210  20.002  -11.624 1.00 43.02  ? 120 PRO L CG  1 
ATOM   4762 C CD  . PRO D 3 121 ? 16.541  20.171  -10.294 1.00 35.98  ? 120 PRO L CD  1 
ATOM   4763 N N   . SER D 3 122 ? 21.029  21.551  -10.281 1.00 46.39  ? 121 SER L N   1 
ATOM   4764 C CA  . SER D 3 122 ? 21.873  22.699  -10.565 1.00 44.92  ? 121 SER L CA  1 
ATOM   4765 C C   . SER D 3 122 ? 22.045  22.881  -12.070 1.00 53.32  ? 121 SER L C   1 
ATOM   4766 O O   . SER D 3 122 ? 21.771  21.983  -12.869 1.00 50.17  ? 121 SER L O   1 
ATOM   4767 C CB  . SER D 3 122 ? 23.240  22.538  -9.895  1.00 48.78  ? 121 SER L CB  1 
ATOM   4768 O OG  . SER D 3 122 ? 23.909  21.383  -10.373 1.00 47.27  ? 121 SER L OG  1 
ATOM   4769 N N   . ASP D 3 123 ? 22.505  24.074  -12.452 1.00 54.43  ? 122 ASP L N   1 
ATOM   4770 C CA  . ASP D 3 123 ? 22.796  24.334  -13.858 1.00 58.48  ? 122 ASP L CA  1 
ATOM   4771 C C   . ASP D 3 123 ? 23.963  23.480  -14.335 1.00 57.61  ? 122 ASP L C   1 
ATOM   4772 O O   . ASP D 3 123 ? 23.982  23.030  -15.489 1.00 54.67  ? 122 ASP L O   1 
ATOM   4773 C CB  . ASP D 3 123 ? 23.095  25.819  -14.066 1.00 64.96  ? 122 ASP L CB  1 
ATOM   4774 C CG  . ASP D 3 123 ? 21.895  26.701  -13.781 1.00 69.44  ? 122 ASP L CG  1 
ATOM   4775 O OD1 . ASP D 3 123 ? 20.940  26.689  -14.586 1.00 74.68  ? 122 ASP L OD1 1 
ATOM   4776 O OD2 . ASP D 3 123 ? 21.904  27.406  -12.749 1.00 68.88  ? 122 ASP L OD2 1 
ATOM   4777 N N   . GLU D 3 124 ? 24.942  23.251  -13.456 1.00 58.09  ? 123 GLU L N   1 
ATOM   4778 C CA  . GLU D 3 124 ? 26.086  22.412  -13.799 1.00 54.86  ? 123 GLU L CA  1 
ATOM   4779 C C   . GLU D 3 124 ? 25.636  21.016  -14.211 1.00 53.53  ? 123 GLU L C   1 
ATOM   4780 O O   . GLU D 3 124 ? 26.116  20.464  -15.208 1.00 59.91  ? 123 GLU L O   1 
ATOM   4781 C CB  . GLU D 3 124 ? 27.057  22.337  -12.617 1.00 56.63  ? 123 GLU L CB  1 
ATOM   4782 C CG  . GLU D 3 124 ? 27.597  23.678  -12.118 1.00 61.78  ? 123 GLU L CG  1 
ATOM   4783 C CD  . GLU D 3 124 ? 26.641  24.407  -11.185 1.00 63.28  ? 123 GLU L CD  1 
ATOM   4784 O OE1 . GLU D 3 124 ? 25.414  24.340  -11.403 1.00 62.21  ? 123 GLU L OE1 1 
ATOM   4785 O OE2 . GLU D 3 124 ? 27.121  25.048  -10.228 1.00 66.55  ? 123 GLU L OE2 1 
ATOM   4786 N N   . GLN D 3 125 ? 24.722  20.419  -13.442 1.00 48.24  ? 124 GLN L N   1 
ATOM   4787 C CA  . GLN D 3 125 ? 24.248  19.081  -13.781 1.00 51.11  ? 124 GLN L CA  1 
ATOM   4788 C C   . GLN D 3 125 ? 23.355  19.101  -15.016 1.00 47.98  ? 124 GLN L C   1 
ATOM   4789 O O   . GLN D 3 125 ? 23.391  18.168  -15.828 1.00 48.62  ? 124 GLN L O   1 
ATOM   4790 C CB  . GLN D 3 125 ? 23.499  18.466  -12.600 1.00 42.82  ? 124 GLN L CB  1 
ATOM   4791 C CG  . GLN D 3 125 ? 23.147  17.002  -12.810 1.00 39.67  ? 124 GLN L CG  1 
ATOM   4792 C CD  . GLN D 3 125 ? 22.157  16.477  -11.792 1.00 42.27  ? 124 GLN L CD  1 
ATOM   4793 O OE1 . GLN D 3 125 ? 21.542  17.244  -11.052 1.00 40.64  ? 124 GLN L OE1 1 
ATOM   4794 N NE2 . GLN D 3 125 ? 21.995  15.158  -11.751 1.00 40.51  ? 124 GLN L NE2 1 
ATOM   4795 N N   . LEU D 3 126 ? 22.547  20.153  -15.176 1.00 53.01  ? 125 LEU L N   1 
ATOM   4796 C CA  . LEU D 3 126 ? 21.643  20.214  -16.320 1.00 52.22  ? 125 LEU L CA  1 
ATOM   4797 C C   . LEU D 3 126 ? 22.403  20.345  -17.633 1.00 52.03  ? 125 LEU L C   1 
ATOM   4798 O O   . LEU D 3 126 ? 21.988  19.781  -18.652 1.00 51.70  ? 125 LEU L O   1 
ATOM   4799 C CB  . LEU D 3 126 ? 20.658  21.371  -16.156 1.00 48.36  ? 125 LEU L CB  1 
ATOM   4800 C CG  . LEU D 3 126 ? 19.538  21.154  -15.139 1.00 43.68  ? 125 LEU L CG  1 
ATOM   4801 C CD1 . LEU D 3 126 ? 18.693  22.410  -14.995 1.00 45.91  ? 125 LEU L CD1 1 
ATOM   4802 C CD2 . LEU D 3 126 ? 18.679  19.967  -15.543 1.00 43.33  ? 125 LEU L CD2 1 
ATOM   4803 N N   . LYS D 3 127 ? 23.522  21.075  -17.634 1.00 53.11  ? 126 LYS L N   1 
ATOM   4804 C CA  . LYS D 3 127 ? 24.324  21.160  -18.851 1.00 51.17  ? 126 LYS L CA  1 
ATOM   4805 C C   . LYS D 3 127 ? 24.905  19.807  -19.252 1.00 56.15  ? 126 LYS L C   1 
ATOM   4806 O O   . LYS D 3 127 ? 25.362  19.653  -20.390 1.00 67.61  ? 126 LYS L O   1 
ATOM   4807 C CB  . LYS D 3 127 ? 25.428  22.209  -18.696 1.00 54.37  ? 126 LYS L CB  1 
ATOM   4808 C CG  . LYS D 3 127 ? 26.691  21.733  -18.012 1.00 62.72  ? 126 LYS L CG  1 
ATOM   4809 C CD  . LYS D 3 127 ? 27.705  22.864  -17.926 1.00 62.50  ? 126 LYS L CD  1 
ATOM   4810 C CE  . LYS D 3 127 ? 27.992  23.451  -19.301 1.00 70.65  ? 126 LYS L CE  1 
ATOM   4811 N NZ  . LYS D 3 127 ? 28.924  24.611  -19.234 1.00 76.58  ? 126 LYS L NZ  1 
ATOM   4812 N N   . SER D 3 128 ? 24.899  18.829  -18.346 1.00 54.58  ? 127 SER L N   1 
ATOM   4813 C CA  . SER D 3 128 ? 25.411  17.495  -18.630 1.00 50.91  ? 127 SER L CA  1 
ATOM   4814 C C   . SER D 3 128 ? 24.325  16.519  -19.068 1.00 50.82  ? 127 SER L C   1 
ATOM   4815 O O   . SER D 3 128 ? 24.648  15.383  -19.432 1.00 55.57  ? 127 SER L O   1 
ATOM   4816 C CB  . SER D 3 128 ? 26.133  16.934  -17.401 1.00 58.61  ? 127 SER L CB  1 
ATOM   4817 O OG  . SER D 3 128 ? 25.214  16.363  -16.487 1.00 61.11  ? 127 SER L OG  1 
ATOM   4818 N N   . GLY D 3 129 ? 23.061  16.925  -19.045 1.00 53.33  ? 128 GLY L N   1 
ATOM   4819 C CA  . GLY D 3 129 ? 21.977  16.104  -19.545 1.00 55.49  ? 128 GLY L CA  1 
ATOM   4820 C C   . GLY D 3 129 ? 21.232  15.257  -18.533 1.00 49.74  ? 128 GLY L C   1 
ATOM   4821 O O   . GLY D 3 129 ? 20.635  14.249  -18.928 1.00 49.58  ? 128 GLY L O   1 
ATOM   4822 N N   . THR D 3 130 ? 21.246  15.625  -17.253 1.00 52.82  ? 129 THR L N   1 
ATOM   4823 C CA  . THR D 3 130 ? 20.541  14.868  -16.227 1.00 51.24  ? 129 THR L CA  1 
ATOM   4824 C C   . THR D 3 130 ? 20.062  15.834  -15.152 1.00 47.18  ? 129 THR L C   1 
ATOM   4825 O O   . THR D 3 130 ? 20.747  16.813  -14.846 1.00 46.73  ? 129 THR L O   1 
ATOM   4826 C CB  . THR D 3 130 ? 21.439  13.781  -15.617 1.00 50.07  ? 129 THR L CB  1 
ATOM   4827 O OG1 . THR D 3 130 ? 21.964  12.951  -16.662 1.00 57.97  ? 129 THR L OG1 1 
ATOM   4828 C CG2 . THR D 3 130 ? 20.654  12.911  -14.646 1.00 47.23  ? 129 THR L CG2 1 
ATOM   4829 N N   . ALA D 3 131 ? 18.882  15.568  -14.591 1.00 44.67  ? 130 ALA L N   1 
ATOM   4830 C CA  . ALA D 3 131 ? 18.293  16.404  -13.551 1.00 44.32  ? 130 ALA L CA  1 
ATOM   4831 C C   . ALA D 3 131 ? 18.035  15.559  -12.311 1.00 39.97  ? 130 ALA L C   1 
ATOM   4832 O O   . ALA D 3 131 ? 17.266  14.591  -12.364 1.00 36.24  ? 130 ALA L O   1 
ATOM   4833 C CB  . ALA D 3 131 ? 16.995  17.053  -14.037 1.00 43.57  ? 130 ALA L CB  1 
ATOM   4834 N N   . SER D 3 132 ? 18.681  15.920  -11.205 1.00 37.76  ? 131 SER L N   1 
ATOM   4835 C CA  . SER D 3 132 ? 18.473  15.281  -9.911  1.00 38.87  ? 131 SER L CA  1 
ATOM   4836 C C   . SER D 3 132 ? 17.772  16.258  -8.975  1.00 34.08  ? 131 SER L C   1 
ATOM   4837 O O   . SER D 3 132 ? 18.306  17.335  -8.684  1.00 39.07  ? 131 SER L O   1 
ATOM   4838 C CB  . SER D 3 132 ? 19.801  14.821  -9.310  1.00 34.36  ? 131 SER L CB  1 
ATOM   4839 O OG  . SER D 3 132 ? 20.417  13.841  -10.126 1.00 34.61  ? 131 SER L OG  1 
ATOM   4840 N N   . VAL D 3 133 ? 16.581  15.885  -8.512  1.00 35.29  ? 132 VAL L N   1 
ATOM   4841 C CA  . VAL D 3 133 ? 15.818  16.661  -7.541  1.00 35.53  ? 132 VAL L CA  1 
ATOM   4842 C C   . VAL D 3 133 ? 15.896  15.942  -6.201  1.00 34.58  ? 132 VAL L C   1 
ATOM   4843 O O   . VAL D 3 133 ? 15.658  14.731  -6.129  1.00 32.24  ? 132 VAL L O   1 
ATOM   4844 C CB  . VAL D 3 133 ? 14.357  16.838  -7.987  1.00 36.08  ? 132 VAL L CB  1 
ATOM   4845 C CG1 . VAL D 3 133 ? 13.653  17.853  -7.106  1.00 39.04  ? 132 VAL L CG1 1 
ATOM   4846 C CG2 . VAL D 3 133 ? 14.296  17.250  -9.453  1.00 38.28  ? 132 VAL L CG2 1 
ATOM   4847 N N   . VAL D 3 134 ? 16.229  16.677  -5.142  1.00 34.63  ? 133 VAL L N   1 
ATOM   4848 C CA  . VAL D 3 134 ? 16.497  16.071  -3.841  1.00 35.81  ? 133 VAL L CA  1 
ATOM   4849 C C   . VAL D 3 134 ? 15.461  16.558  -2.836  1.00 33.07  ? 133 VAL L C   1 
ATOM   4850 O O   . VAL D 3 134 ? 15.185  17.758  -2.752  1.00 35.64  ? 133 VAL L O   1 
ATOM   4851 C CB  . VAL D 3 134 ? 17.925  16.381  -3.355  1.00 38.51  ? 133 VAL L CB  1 
ATOM   4852 C CG1 . VAL D 3 134 ? 18.157  15.794  -1.972  1.00 31.24  ? 133 VAL L CG1 1 
ATOM   4853 C CG2 . VAL D 3 134 ? 18.944  15.833  -4.342  1.00 35.46  ? 133 VAL L CG2 1 
ATOM   4854 N N   . CYS D 3 135 ? 14.881  15.625  -2.084  1.00 30.64  ? 134 CYS L N   1 
ATOM   4855 C CA  . CYS D 3 135 ? 13.950  15.929  -1.006  1.00 35.64  ? 134 CYS L CA  1 
ATOM   4856 C C   . CYS D 3 135 ? 14.552  15.425  0.298   1.00 36.51  ? 134 CYS L C   1 
ATOM   4857 O O   . CYS D 3 135 ? 14.903  14.245  0.410   1.00 35.41  ? 134 CYS L O   1 
ATOM   4858 C CB  . CYS D 3 135 ? 12.583  15.286  -1.263  1.00 36.67  ? 134 CYS L CB  1 
ATOM   4859 S SG  . CYS D 3 135 ? 11.270  15.700  -0.076  1.00 43.42  ? 134 CYS L SG  1 
ATOM   4860 N N   . LEU D 3 136 ? 14.671  16.317  1.276   1.00 36.82  ? 135 LEU L N   1 
ATOM   4861 C CA  . LEU D 3 136 ? 15.303  16.022  2.554   1.00 39.13  ? 135 LEU L CA  1 
ATOM   4862 C C   . LEU D 3 136 ? 14.272  16.065  3.673   1.00 35.70  ? 135 LEU L C   1 
ATOM   4863 O O   . LEU D 3 136 ? 13.538  17.051  3.810   1.00 34.67  ? 135 LEU L O   1 
ATOM   4864 C CB  . LEU D 3 136 ? 16.429  17.016  2.845   1.00 34.30  ? 135 LEU L CB  1 
ATOM   4865 C CG  . LEU D 3 136 ? 17.005  16.974  4.261   1.00 32.93  ? 135 LEU L CG  1 
ATOM   4866 C CD1 . LEU D 3 136 ? 17.732  15.660  4.508   1.00 28.03  ? 135 LEU L CD1 1 
ATOM   4867 C CD2 . LEU D 3 136 ? 17.926  18.159  4.504   1.00 35.32  ? 135 LEU L CD2 1 
ATOM   4868 N N   . LEU D 3 137 ? 14.228  14.994  4.466   1.00 32.41  ? 136 LEU L N   1 
ATOM   4869 C CA  . LEU D 3 137 ? 13.452  14.911  5.698   1.00 33.93  ? 136 LEU L CA  1 
ATOM   4870 C C   . LEU D 3 137 ? 14.459  14.893  6.842   1.00 32.82  ? 136 LEU L C   1 
ATOM   4871 O O   . LEU D 3 137 ? 15.221  13.932  6.989   1.00 28.18  ? 136 LEU L O   1 
ATOM   4872 C CB  . LEU D 3 137 ? 12.571  13.662  5.714   1.00 32.19  ? 136 LEU L CB  1 
ATOM   4873 C CG  . LEU D 3 137 ? 11.327  13.563  4.824   1.00 35.98  ? 136 LEU L CG  1 
ATOM   4874 C CD1 . LEU D 3 137 ? 11.655  13.604  3.336   1.00 33.90  ? 136 LEU L CD1 1 
ATOM   4875 C CD2 . LEU D 3 137 ? 10.572  12.285  5.159   1.00 32.47  ? 136 LEU L CD2 1 
ATOM   4876 N N   . ASN D 3 138 ? 14.468  15.952  7.643   1.00 32.63  ? 137 ASN L N   1 
ATOM   4877 C CA  . ASN D 3 138 ? 15.520  16.192  8.620   1.00 33.92  ? 137 ASN L CA  1 
ATOM   4878 C C   . ASN D 3 138 ? 14.983  15.963  10.027  1.00 35.67  ? 137 ASN L C   1 
ATOM   4879 O O   . ASN D 3 138 ? 13.962  16.550  10.411  1.00 35.06  ? 137 ASN L O   1 
ATOM   4880 C CB  . ASN D 3 138 ? 16.067  17.613  8.472   1.00 33.58  ? 137 ASN L CB  1 
ATOM   4881 C CG  . ASN D 3 138 ? 17.353  17.829  9.241   1.00 36.10  ? 137 ASN L CG  1 
ATOM   4882 O OD1 . ASN D 3 138 ? 18.408  17.318  8.865   1.00 38.31  ? 137 ASN L OD1 1 
ATOM   4883 N ND2 . ASN D 3 138 ? 17.275  18.602  10.317  1.00 41.43  ? 137 ASN L ND2 1 
ATOM   4884 N N   . ASN D 3 139 ? 15.663  15.085  10.771  1.00 31.05  ? 138 ASN L N   1 
ATOM   4885 C CA  . ASN D 3 139 ? 15.534  14.932  12.222  1.00 30.68  ? 138 ASN L CA  1 
ATOM   4886 C C   . ASN D 3 139 ? 14.092  14.612  12.629  1.00 32.46  ? 138 ASN L C   1 
ATOM   4887 O O   . ASN D 3 139 ? 13.377  15.434  13.204  1.00 37.31  ? 138 ASN L O   1 
ATOM   4888 C CB  . ASN D 3 139 ? 16.049  16.181  12.948  1.00 33.76  ? 138 ASN L CB  1 
ATOM   4889 C CG  . ASN D 3 139 ? 17.530  16.416  12.726  1.00 35.40  ? 138 ASN L CG  1 
ATOM   4890 O OD1 . ASN D 3 139 ? 18.259  15.514  12.310  1.00 36.33  ? 138 ASN L OD1 1 
ATOM   4891 N ND2 . ASN D 3 139 ? 17.986  17.630  13.013  1.00 42.01  ? 138 ASN L ND2 1 
ATOM   4892 N N   . PHE D 3 140 ? 13.680  13.386  12.316  1.00 28.19  ? 139 PHE L N   1 
ATOM   4893 C CA  . PHE D 3 140 ? 12.350  12.929  12.684  1.00 31.88  ? 139 PHE L CA  1 
ATOM   4894 C C   . PHE D 3 140 ? 12.415  11.626  13.472  1.00 27.56  ? 139 PHE L C   1 
ATOM   4895 O O   . PHE D 3 140 ? 13.404  10.888  13.427  1.00 26.43  ? 139 PHE L O   1 
ATOM   4896 C CB  . PHE D 3 140 ? 11.447  12.751  11.453  1.00 28.29  ? 139 PHE L CB  1 
ATOM   4897 C CG  . PHE D 3 140 ? 11.930  11.718  10.472  1.00 27.50  ? 139 PHE L CG  1 
ATOM   4898 C CD1 . PHE D 3 140 ? 12.837  12.050  9.480   1.00 28.74  ? 139 PHE L CD1 1 
ATOM   4899 C CD2 . PHE D 3 140 ? 11.441  10.422  10.519  1.00 24.36  ? 139 PHE L CD2 1 
ATOM   4900 C CE1 . PHE D 3 140 ? 13.268  11.102  8.569   1.00 26.54  ? 139 PHE L CE1 1 
ATOM   4901 C CE2 . PHE D 3 140 ? 11.868  9.470   9.612   1.00 28.30  ? 139 PHE L CE2 1 
ATOM   4902 C CZ  . PHE D 3 140 ? 12.782  9.811   8.635   1.00 28.92  ? 139 PHE L CZ  1 
ATOM   4903 N N   . TYR D 3 141 ? 11.330  11.363  14.205  1.00 27.42  ? 140 TYR L N   1 
ATOM   4904 C CA  . TYR D 3 141 ? 11.108  10.134  14.952  1.00 28.90  ? 140 TYR L CA  1 
ATOM   4905 C C   . TYR D 3 141 ? 9.620   10.061  15.243  1.00 27.38  ? 140 TYR L C   1 
ATOM   4906 O O   . TYR D 3 141 ? 9.023   11.097  15.568  1.00 32.47  ? 140 TYR L O   1 
ATOM   4907 C CB  . TYR D 3 141 ? 11.909  10.086  16.260  1.00 26.14  ? 140 TYR L CB  1 
ATOM   4908 C CG  . TYR D 3 141 ? 11.783  8.757   16.970  1.00 25.35  ? 140 TYR L CG  1 
ATOM   4909 C CD1 . TYR D 3 141 ? 12.603  7.690   16.632  1.00 25.67  ? 140 TYR L CD1 1 
ATOM   4910 C CD2 . TYR D 3 141 ? 10.815  8.555   17.945  1.00 24.55  ? 140 TYR L CD2 1 
ATOM   4911 C CE1 . TYR D 3 141 ? 12.482  6.467   17.263  1.00 35.45  ? 140 TYR L CE1 1 
ATOM   4912 C CE2 . TYR D 3 141 ? 10.685  7.334   18.580  1.00 24.45  ? 140 TYR L CE2 1 
ATOM   4913 C CZ  . TYR D 3 141 ? 11.522  6.295   18.234  1.00 30.02  ? 140 TYR L CZ  1 
ATOM   4914 O OH  . TYR D 3 141 ? 11.398  5.079   18.863  1.00 34.86  ? 140 TYR L OH  1 
ATOM   4915 N N   . PRO D 3 142 ? 8.986   8.883   15.148  1.00 28.59  ? 141 PRO L N   1 
ATOM   4916 C CA  . PRO D 3 142 ? 9.540   7.561   14.801  1.00 26.43  ? 141 PRO L CA  1 
ATOM   4917 C C   . PRO D 3 142 ? 9.967   7.418   13.341  1.00 27.65  ? 141 PRO L C   1 
ATOM   4918 O O   . PRO D 3 142 ? 9.896   8.358   12.554  1.00 29.55  ? 141 PRO L O   1 
ATOM   4919 C CB  . PRO D 3 142 ? 8.386   6.609   15.151  1.00 32.34  ? 141 PRO L CB  1 
ATOM   4920 C CG  . PRO D 3 142 ? 7.155   7.435   14.956  1.00 35.21  ? 141 PRO L CG  1 
ATOM   4921 C CD  . PRO D 3 142 ? 7.541   8.808   15.434  1.00 29.55  ? 141 PRO L CD  1 
ATOM   4922 N N   . ARG D 3 143 ? 10.415  6.216   12.972  1.00 29.85  ? 142 ARG L N   1 
ATOM   4923 C CA  . ARG D 3 143 ? 11.051  6.014   11.675  1.00 27.97  ? 142 ARG L CA  1 
ATOM   4924 C C   . ARG D 3 143 ? 10.050  6.068   10.524  1.00 28.10  ? 142 ARG L C   1 
ATOM   4925 O O   . ARG D 3 143 ? 10.383  6.563   9.442   1.00 30.26  ? 142 ARG L O   1 
ATOM   4926 C CB  . ARG D 3 143 ? 11.791  4.674   11.676  1.00 26.39  ? 142 ARG L CB  1 
ATOM   4927 C CG  . ARG D 3 143 ? 12.154  4.134   10.303  1.00 29.48  ? 142 ARG L CG  1 
ATOM   4928 C CD  . ARG D 3 143 ? 13.257  4.963   9.662   1.00 30.96  ? 142 ARG L CD  1 
ATOM   4929 N NE  . ARG D 3 143 ? 13.641  4.439   8.358   1.00 36.79  ? 142 ARG L NE  1 
ATOM   4930 C CZ  . ARG D 3 143 ? 13.087  4.812   7.213   1.00 38.53  ? 142 ARG L CZ  1 
ATOM   4931 N NH1 . ARG D 3 143 ? 12.142  5.735   7.173   1.00 36.28  ? 142 ARG L NH1 1 
ATOM   4932 N NH2 . ARG D 3 143 ? 13.496  4.248   6.080   1.00 42.39  ? 142 ARG L NH2 1 
ATOM   4933 N N   . GLU D 3 144 ? 8.824   5.592   10.739  1.00 27.72  ? 143 GLU L N   1 
ATOM   4934 C CA  . GLU D 3 144 ? 7.874   5.436   9.642   1.00 31.40  ? 143 GLU L CA  1 
ATOM   4935 C C   . GLU D 3 144 ? 7.462   6.788   9.073   1.00 35.08  ? 143 GLU L C   1 
ATOM   4936 O O   . GLU D 3 144 ? 7.135   7.718   9.818   1.00 35.94  ? 143 GLU L O   1 
ATOM   4937 C CB  . GLU D 3 144 ? 6.637   4.665   10.104  1.00 35.61  ? 143 GLU L CB  1 
ATOM   4938 C CG  . GLU D 3 144 ? 6.888   3.200   10.435  1.00 33.78  ? 143 GLU L CG  1 
ATOM   4939 C CD  . GLU D 3 144 ? 7.500   3.003   11.808  1.00 36.08  ? 143 GLU L CD  1 
ATOM   4940 O OE1 . GLU D 3 144 ? 7.632   3.996   12.552  1.00 33.18  ? 143 GLU L OE1 1 
ATOM   4941 O OE2 . GLU D 3 144 ? 7.855   1.853   12.141  1.00 36.72  ? 143 GLU L OE2 1 
ATOM   4942 N N   . ALA D 3 145 ? 7.478   6.888   7.748   1.00 35.99  ? 144 ALA L N   1 
ATOM   4943 C CA  . ALA D 3 145 ? 7.051   8.083   7.032   1.00 40.57  ? 144 ALA L CA  1 
ATOM   4944 C C   . ALA D 3 145 ? 6.662   7.666   5.619   1.00 39.05  ? 144 ALA L C   1 
ATOM   4945 O O   . ALA D 3 145 ? 6.761   6.493   5.249   1.00 40.12  ? 144 ALA L O   1 
ATOM   4946 C CB  . ALA D 3 145 ? 8.149   9.151   7.026   1.00 32.77  ? 144 ALA L CB  1 
ATOM   4947 N N   . LYS D 3 146 ? 6.198   8.633   4.831   1.00 38.27  ? 145 LYS L N   1 
ATOM   4948 C CA  . LYS D 3 146 ? 5.906   8.379   3.425   1.00 38.60  ? 145 LYS L CA  1 
ATOM   4949 C C   . LYS D 3 146 ? 6.317   9.576   2.583   1.00 38.86  ? 145 LYS L C   1 
ATOM   4950 O O   . LYS D 3 146 ? 5.948   10.713  2.893   1.00 37.73  ? 145 LYS L O   1 
ATOM   4951 C CB  . LYS D 3 146 ? 4.423   8.063   3.203   1.00 42.73  ? 145 LYS L CB  1 
ATOM   4952 C CG  . LYS D 3 146 ? 4.084   7.755   1.750   1.00 46.36  ? 145 LYS L CG  1 
ATOM   4953 C CD  . LYS D 3 146 ? 2.808   6.940   1.630   1.00 48.69  ? 145 LYS L CD  1 
ATOM   4954 C CE  . LYS D 3 146 ? 3.088   5.596   0.973   0.50 51.65  ? 145 LYS L CE  1 
ATOM   4955 N NZ  . LYS D 3 146 ? 4.175   4.855   1.674   1.00 61.14  ? 145 LYS L NZ  1 
ATOM   4956 N N   . VAL D 3 147 ? 7.072   9.309   1.520   1.00 38.98  ? 146 VAL L N   1 
ATOM   4957 C CA  . VAL D 3 147 ? 7.541   10.325  0.585   1.00 37.43  ? 146 VAL L CA  1 
ATOM   4958 C C   . VAL D 3 147 ? 6.931   10.027  -0.778  1.00 37.37  ? 146 VAL L C   1 
ATOM   4959 O O   . VAL D 3 147 ? 7.117   8.929   -1.319  1.00 39.81  ? 146 VAL L O   1 
ATOM   4960 C CB  . VAL D 3 147 ? 9.075   10.354  0.502   1.00 39.11  ? 146 VAL L CB  1 
ATOM   4961 C CG1 . VAL D 3 147 ? 9.539   11.420  -0.480  1.00 39.46  ? 146 VAL L CG1 1 
ATOM   4962 C CG2 . VAL D 3 147 ? 9.680   10.581  1.879   1.00 40.82  ? 146 VAL L CG2 1 
ATOM   4963 N N   . GLN D 3 148 ? 6.205   10.997  -1.331  1.00 38.44  ? 147 GLN L N   1 
ATOM   4964 C CA  . GLN D 3 148 ? 5.578   10.864  -2.641  1.00 41.03  ? 147 GLN L CA  1 
ATOM   4965 C C   . GLN D 3 148 ? 6.061   11.988  -3.546  1.00 38.48  ? 147 GLN L C   1 
ATOM   4966 O O   . GLN D 3 148 ? 5.896   13.167  -3.215  1.00 43.47  ? 147 GLN L O   1 
ATOM   4967 C CB  . GLN D 3 148 ? 4.052   10.882  -2.528  1.00 40.69  ? 147 GLN L CB  1 
ATOM   4968 C CG  . GLN D 3 148 ? 3.400   9.508   -2.610  1.00 53.49  ? 147 GLN L CG  1 
ATOM   4969 C CD  . GLN D 3 148 ? 3.481   8.899   -3.999  1.00 54.50  ? 147 GLN L CD  1 
ATOM   4970 O OE1 . GLN D 3 148 ? 3.810   9.579   -4.971  1.00 50.81  ? 147 GLN L OE1 1 
ATOM   4971 N NE2 . GLN D 3 148 ? 3.175   7.612   -4.098  1.00 57.95  ? 147 GLN L NE2 1 
ATOM   4972 N N   . TRP D 3 149 ? 6.654   11.627  -4.680  1.00 37.68  ? 148 TRP L N   1 
ATOM   4973 C CA  . TRP D 3 149 ? 7.031   12.616  -5.679  1.00 37.52  ? 148 TRP L CA  1 
ATOM   4974 C C   . TRP D 3 149 ? 5.849   12.930  -6.586  1.00 36.35  ? 148 TRP L C   1 
ATOM   4975 O O   . TRP D 3 149 ? 5.115   12.031  -7.008  1.00 40.52  ? 148 TRP L O   1 
ATOM   4976 C CB  . TRP D 3 149 ? 8.217   12.125  -6.510  1.00 37.01  ? 148 TRP L CB  1 
ATOM   4977 C CG  . TRP D 3 149 ? 9.538   12.238  -5.812  1.00 36.21  ? 148 TRP L CG  1 
ATOM   4978 C CD1 . TRP D 3 149 ? 10.228  11.238  -5.193  1.00 36.63  ? 148 TRP L CD1 1 
ATOM   4979 C CD2 . TRP D 3 149 ? 10.330  13.423  -5.665  1.00 36.02  ? 148 TRP L CD2 1 
ATOM   4980 N NE1 . TRP D 3 149 ? 11.401  11.727  -4.668  1.00 36.78  ? 148 TRP L NE1 1 
ATOM   4981 C CE2 . TRP D 3 149 ? 11.487  13.066  -4.946  1.00 37.15  ? 148 TRP L CE2 1 
ATOM   4982 C CE3 . TRP D 3 149 ? 10.174  14.752  -6.074  1.00 35.96  ? 148 TRP L CE3 1 
ATOM   4983 C CZ2 . TRP D 3 149 ? 12.480  13.989  -4.624  1.00 35.56  ? 148 TRP L CZ2 1 
ATOM   4984 C CZ3 . TRP D 3 149 ? 11.162  15.666  -5.755  1.00 37.68  ? 148 TRP L CZ3 1 
ATOM   4985 C CH2 . TRP D 3 149 ? 12.299  15.281  -5.036  1.00 37.65  ? 148 TRP L CH2 1 
ATOM   4986 N N   . LYS D 3 150 ? 5.668   14.216  -6.881  1.00 38.49  ? 149 LYS L N   1 
ATOM   4987 C CA  . LYS D 3 150 ? 4.604   14.684  -7.761  1.00 42.78  ? 149 LYS L CA  1 
ATOM   4988 C C   . LYS D 3 150 ? 5.205   15.619  -8.797  1.00 46.81  ? 149 LYS L C   1 
ATOM   4989 O O   . LYS D 3 150 ? 5.843   16.617  -8.446  1.00 44.75  ? 149 LYS L O   1 
ATOM   4990 C CB  . LYS D 3 150 ? 3.502   15.401  -6.975  1.00 44.00  ? 149 LYS L CB  1 
ATOM   4991 C CG  . LYS D 3 150 ? 2.565   14.491  -6.197  1.00 48.98  ? 149 LYS L CG  1 
ATOM   4992 C CD  . LYS D 3 150 ? 1.592   15.317  -5.368  1.00 48.33  ? 149 LYS L CD  1 
ATOM   4993 C CE  . LYS D 3 150 ? 0.528   14.455  -4.710  1.00 58.06  ? 149 LYS L CE  1 
ATOM   4994 N NZ  . LYS D 3 150 ? -0.617  14.203  -5.629  1.00 58.61  ? 149 LYS L NZ  1 
ATOM   4995 N N   . VAL D 3 151 ? 4.999   15.296  -10.069 1.00 43.32  ? 150 VAL L N   1 
ATOM   4996 C CA  . VAL D 3 151 ? 5.451   16.121  -11.181 1.00 46.53  ? 150 VAL L CA  1 
ATOM   4997 C C   . VAL D 3 151 ? 4.203   16.581  -11.918 1.00 45.72  ? 150 VAL L C   1 
ATOM   4998 O O   . VAL D 3 151 ? 3.534   15.776  -12.581 1.00 48.09  ? 150 VAL L O   1 
ATOM   4999 C CB  . VAL D 3 151 ? 6.405   15.362  -12.112 1.00 50.01  ? 150 VAL L CB  1 
ATOM   5000 C CG1 . VAL D 3 151 ? 6.850   16.257  -13.244 1.00 44.63  ? 150 VAL L CG1 1 
ATOM   5001 C CG2 . VAL D 3 151 ? 7.610   14.860  -11.334 1.00 43.52  ? 150 VAL L CG2 1 
ATOM   5002 N N   . ASP D 3 152 ? 3.901   17.875  -11.821 1.00 48.84  ? 151 ASP L N   1 
ATOM   5003 C CA  . ASP D 3 152 ? 2.644   18.438  -12.314 1.00 50.17  ? 151 ASP L CA  1 
ATOM   5004 C C   . ASP D 3 152 ? 1.449   17.636  -11.797 1.00 49.97  ? 151 ASP L C   1 
ATOM   5005 O O   . ASP D 3 152 ? 0.546   17.258  -12.547 1.00 51.20  ? 151 ASP L O   1 
ATOM   5006 C CB  . ASP D 3 152 ? 2.637   18.519  -13.843 1.00 50.58  ? 151 ASP L CB  1 
ATOM   5007 C CG  . ASP D 3 152 ? 3.583   19.579  -14.375 1.00 47.41  ? 151 ASP L CG  1 
ATOM   5008 O OD1 . ASP D 3 152 ? 3.838   20.568  -13.656 1.00 47.54  ? 151 ASP L OD1 1 
ATOM   5009 O OD2 . ASP D 3 152 ? 4.066   19.427  -15.517 1.00 50.97  ? 151 ASP L OD2 1 
ATOM   5010 N N   . ASN D 3 153 ? 1.465   17.367  -10.489 1.00 47.96  ? 152 ASN L N   1 
ATOM   5011 C CA  . ASN D 3 153 ? 0.425   16.651  -9.750  1.00 47.38  ? 152 ASN L CA  1 
ATOM   5012 C C   . ASN D 3 153 ? 0.311   15.182  -10.145 1.00 43.80  ? 152 ASN L C   1 
ATOM   5013 O O   . ASN D 3 153 ? -0.634  14.505  -9.719  1.00 49.51  ? 152 ASN L O   1 
ATOM   5014 C CB  . ASN D 3 153 ? -0.943  17.330  -9.897  1.00 53.24  ? 152 ASN L CB  1 
ATOM   5015 C CG  . ASN D 3 153 ? -1.878  17.021  -8.742  1.00 57.62  ? 152 ASN L CG  1 
ATOM   5016 O OD1 . ASN D 3 153 ? -1.458  16.956  -7.587  1.00 61.31  ? 152 ASN L OD1 1 
ATOM   5017 N ND2 . ASN D 3 153 ? -3.153  16.823  -9.052  1.00 50.41  ? 152 ASN L ND2 1 
ATOM   5018 N N   . ALA D 3 154 ? 1.246   14.664  -10.938 1.00 45.11  ? 153 ALA L N   1 
ATOM   5019 C CA  . ALA D 3 154 ? 1.246   13.260  -11.335 1.00 44.10  ? 153 ALA L CA  1 
ATOM   5020 C C   . ALA D 3 154 ? 2.138   12.453  -10.401 1.00 45.34  ? 153 ALA L C   1 
ATOM   5021 O O   . ALA D 3 154 ? 3.290   12.827  -10.157 1.00 45.64  ? 153 ALA L O   1 
ATOM   5022 C CB  . ALA D 3 154 ? 1.715   13.106  -12.782 1.00 46.83  ? 153 ALA L CB  1 
ATOM   5023 N N   . LEU D 3 155 ? 1.604   11.350  -9.878  1.00 44.73  ? 154 LEU L N   1 
ATOM   5024 C CA  . LEU D 3 155 ? 2.347   10.541  -8.920  1.00 39.13  ? 154 LEU L CA  1 
ATOM   5025 C C   . LEU D 3 155 ? 3.490   9.821   -9.623  1.00 42.94  ? 154 LEU L C   1 
ATOM   5026 O O   . LEU D 3 155 ? 3.280   9.139   -10.630 1.00 43.25  ? 154 LEU L O   1 
ATOM   5027 C CB  . LEU D 3 155 ? 1.440   9.510   -8.239  1.00 43.22  ? 154 LEU L CB  1 
ATOM   5028 C CG  . LEU D 3 155 ? 0.228   9.869   -7.366  1.00 56.29  ? 154 LEU L CG  1 
ATOM   5029 C CD1 . LEU D 3 155 ? -0.808  10.688  -8.130  1.00 56.34  ? 154 LEU L CD1 1 
ATOM   5030 C CD2 . LEU D 3 155 ? -0.401  8.630   -6.735  1.00 58.45  ? 154 LEU L CD2 1 
ATOM   5031 N N   . GLN D 3 156 ? 4.699   9.971   -9.095  1.00 40.12  ? 155 GLN L N   1 
ATOM   5032 C CA  . GLN D 3 156 ? 5.871   9.322   -9.661  1.00 39.25  ? 155 GLN L CA  1 
ATOM   5033 C C   . GLN D 3 156 ? 6.089   7.954   -9.026  1.00 42.60  ? 155 GLN L C   1 
ATOM   5034 O O   . GLN D 3 156 ? 5.792   7.737   -7.848  1.00 46.40  ? 155 GLN L O   1 
ATOM   5035 C CB  . GLN D 3 156 ? 7.116   10.190  -9.476  1.00 40.06  ? 155 GLN L CB  1 
ATOM   5036 C CG  . GLN D 3 156 ? 7.003   11.543  -10.141 1.00 41.58  ? 155 GLN L CG  1 
ATOM   5037 C CD  . GLN D 3 156 ? 6.736   11.426  -11.629 1.00 41.74  ? 155 GLN L CD  1 
ATOM   5038 O OE1 . GLN D 3 156 ? 7.581   10.947  -12.386 1.00 37.05  ? 155 GLN L OE1 1 
ATOM   5039 N NE2 . GLN D 3 156 ? 5.552   11.851  -12.054 1.00 41.16  ? 155 GLN L NE2 1 
ATOM   5040 N N   . SER D 3 157 ? 6.612   7.027   -9.825  1.00 43.52  ? 156 SER L N   1 
ATOM   5041 C CA  . SER D 3 157 ? 6.863   5.671   -9.358  1.00 43.44  ? 156 SER L CA  1 
ATOM   5042 C C   . SER D 3 157 ? 8.018   5.070   -10.143 1.00 43.20  ? 156 SER L C   1 
ATOM   5043 O O   . SER D 3 157 ? 8.052   5.165   -11.373 1.00 42.33  ? 156 SER L O   1 
ATOM   5044 C CB  . SER D 3 157 ? 5.611   4.799   -9.504  1.00 48.33  ? 156 SER L CB  1 
ATOM   5045 O OG  . SER D 3 157 ? 5.848   3.484   -9.034  1.00 55.28  ? 156 SER L OG  1 
ATOM   5046 N N   . GLY D 3 158 ? 8.956   4.453   -9.427  1.00 43.20  ? 157 GLY L N   1 
ATOM   5047 C CA  . GLY D 3 158 ? 10.054  3.739   -10.045 1.00 38.29  ? 157 GLY L CA  1 
ATOM   5048 C C   . GLY D 3 158 ? 11.195  4.583   -10.566 1.00 44.12  ? 157 GLY L C   1 
ATOM   5049 O O   . GLY D 3 158 ? 12.071  4.045   -11.252 1.00 41.92  ? 157 GLY L O   1 
ATOM   5050 N N   . ASN D 3 159 ? 11.228  5.882   -10.265 1.00 33.14  ? 158 ASN L N   1 
ATOM   5051 C CA  . ASN D 3 159 ? 12.302  6.742   -10.750 1.00 34.79  ? 158 ASN L CA  1 
ATOM   5052 C C   . ASN D 3 159 ? 12.911  7.560   -9.618  1.00 34.64  ? 158 ASN L C   1 
ATOM   5053 O O   . ASN D 3 159 ? 13.438  8.652   -9.846  1.00 35.58  ? 158 ASN L O   1 
ATOM   5054 C CB  . ASN D 3 159 ? 11.816  7.657   -11.874 1.00 32.30  ? 158 ASN L CB  1 
ATOM   5055 C CG  . ASN D 3 159 ? 10.631  8.505   -11.467 1.00 40.53  ? 158 ASN L CG  1 
ATOM   5056 O OD1 . ASN D 3 159 ? 9.990   8.250   -10.449 1.00 37.94  ? 158 ASN L OD1 1 
ATOM   5057 N ND2 . ASN D 3 159 ? 10.336  9.526   -12.264 1.00 37.82  ? 158 ASN L ND2 1 
ATOM   5058 N N   . SER D 3 160 ? 12.844  7.048   -8.391  1.00 33.38  ? 159 SER L N   1 
ATOM   5059 C CA  . SER D 3 160 ? 13.456  7.702   -7.246  1.00 32.64  ? 159 SER L CA  1 
ATOM   5060 C C   . SER D 3 160 ? 14.173  6.663   -6.398  1.00 37.45  ? 159 SER L C   1 
ATOM   5061 O O   . SER D 3 160 ? 13.817  5.482   -6.401  1.00 35.47  ? 159 SER L O   1 
ATOM   5062 C CB  . SER D 3 160 ? 12.422  8.449   -6.392  1.00 32.85  ? 159 SER L CB  1 
ATOM   5063 O OG  . SER D 3 160 ? 11.460  7.557   -5.857  1.00 31.46  ? 159 SER L OG  1 
ATOM   5064 N N   . GLN D 3 161 ? 15.189  7.122   -5.672  1.00 37.97  ? 160 GLN L N   1 
ATOM   5065 C CA  . GLN D 3 161 ? 15.923  6.278   -4.737  1.00 34.19  ? 160 GLN L CA  1 
ATOM   5066 C C   . GLN D 3 161 ? 16.140  7.049   -3.447  1.00 37.30  ? 160 GLN L C   1 
ATOM   5067 O O   . GLN D 3 161 ? 16.421  8.247   -3.477  1.00 35.72  ? 160 GLN L O   1 
ATOM   5068 C CB  . GLN D 3 161 ? 17.276  5.832   -5.307  1.00 37.61  ? 160 GLN L CB  1 
ATOM   5069 C CG  . GLN D 3 161 ? 17.196  4.713   -6.330  1.00 39.35  ? 160 GLN L CG  1 
ATOM   5070 C CD  . GLN D 3 161 ? 18.565  4.230   -6.765  1.00 36.89  ? 160 GLN L CD  1 
ATOM   5071 O OE1 . GLN D 3 161 ? 19.433  5.027   -7.121  1.00 39.54  ? 160 GLN L OE1 1 
ATOM   5072 N NE2 . GLN D 3 161 ? 18.766  2.918   -6.736  1.00 39.69  ? 160 GLN L NE2 1 
ATOM   5073 N N   . GLU D 3 162 ? 16.043  6.362   -2.314  1.00 35.80  ? 161 GLU L N   1 
ATOM   5074 C CA  . GLU D 3 162 ? 16.152  7.032   -1.028  1.00 36.77  ? 161 GLU L CA  1 
ATOM   5075 C C   . GLU D 3 162 ? 17.192  6.346   -0.155  1.00 35.84  ? 161 GLU L C   1 
ATOM   5076 O O   . GLU D 3 162 ? 17.548  5.183   -0.357  1.00 33.92  ? 161 GLU L O   1 
ATOM   5077 C CB  . GLU D 3 162 ? 14.800  7.085   -0.301  1.00 34.84  ? 161 GLU L CB  1 
ATOM   5078 C CG  . GLU D 3 162 ? 14.355  5.774   0.316   1.00 36.35  ? 161 GLU L CG  1 
ATOM   5079 C CD  . GLU D 3 162 ? 12.997  5.886   0.978   1.00 42.11  ? 161 GLU L CD  1 
ATOM   5080 O OE1 . GLU D 3 162 ? 12.184  6.721   0.529   1.00 44.79  ? 161 GLU L OE1 1 
ATOM   5081 O OE2 . GLU D 3 162 ? 12.746  5.145   1.951   1.00 52.44  ? 161 GLU L OE2 1 
ATOM   5082 N N   . SER D 3 163 ? 17.674  7.104   0.827   1.00 35.35  ? 162 SER L N   1 
ATOM   5083 C CA  . SER D 3 163 ? 18.679  6.639   1.769   1.00 35.10  ? 162 SER L CA  1 
ATOM   5084 C C   . SER D 3 163 ? 18.400  7.266   3.126   1.00 32.99  ? 162 SER L C   1 
ATOM   5085 O O   . SER D 3 163 ? 17.960  8.414   3.205   1.00 34.62  ? 162 SER L O   1 
ATOM   5086 C CB  . SER D 3 163 ? 20.088  7.007   1.288   1.00 36.21  ? 162 SER L CB  1 
ATOM   5087 O OG  . SER D 3 163 ? 21.050  6.829   2.311   1.00 41.52  ? 162 SER L OG  1 
ATOM   5088 N N   . VAL D 3 164 ? 18.667  6.517   4.191   1.00 33.17  ? 163 VAL L N   1 
ATOM   5089 C CA  . VAL D 3 164 ? 18.337  6.947   5.543   1.00 35.34  ? 163 VAL L CA  1 
ATOM   5090 C C   . VAL D 3 164 ? 19.560  6.778   6.434   1.00 32.51  ? 163 VAL L C   1 
ATOM   5091 O O   . VAL D 3 164 ? 20.266  5.766   6.354   1.00 36.36  ? 163 VAL L O   1 
ATOM   5092 C CB  . VAL D 3 164 ? 17.122  6.171   6.102   1.00 32.01  ? 163 VAL L CB  1 
ATOM   5093 C CG1 . VAL D 3 164 ? 17.358  4.667   6.043   1.00 38.10  ? 163 VAL L CG1 1 
ATOM   5094 C CG2 . VAL D 3 164 ? 16.795  6.620   7.521   1.00 29.69  ? 163 VAL L CG2 1 
ATOM   5095 N N   . THR D 3 165 ? 19.821  7.782   7.268   1.00 29.42  ? 164 THR L N   1 
ATOM   5096 C CA  . THR D 3 165 ? 20.911  7.696   8.224   1.00 32.82  ? 164 THR L CA  1 
ATOM   5097 C C   . THR D 3 165 ? 20.543  6.760   9.372   1.00 37.06  ? 164 THR L C   1 
ATOM   5098 O O   . THR D 3 165 ? 19.377  6.419   9.588   1.00 31.41  ? 164 THR L O   1 
ATOM   5099 C CB  . THR D 3 165 ? 21.254  9.076   8.785   1.00 33.50  ? 164 THR L CB  1 
ATOM   5100 O OG1 . THR D 3 165 ? 20.122  9.601   9.490   1.00 34.18  ? 164 THR L OG1 1 
ATOM   5101 C CG2 . THR D 3 165 ? 21.633  10.031  7.665   1.00 31.52  ? 164 THR L CG2 1 
ATOM   5102 N N   . GLU D 3 166 ? 21.565  6.344   10.115  1.00 31.57  ? 165 GLU L N   1 
ATOM   5103 C CA  . GLU D 3 166 ? 21.335  5.630   11.358  1.00 31.32  ? 165 GLU L CA  1 
ATOM   5104 C C   . GLU D 3 166 ? 20.777  6.582   12.413  1.00 32.33  ? 165 GLU L C   1 
ATOM   5105 O O   . GLU D 3 166 ? 20.803  7.808   12.264  1.00 34.20  ? 165 GLU L O   1 
ATOM   5106 C CB  . GLU D 3 166 ? 22.627  4.976   11.850  1.00 30.58  ? 165 GLU L CB  1 
ATOM   5107 C CG  . GLU D 3 166 ? 23.144  3.872   10.944  1.00 38.30  ? 165 GLU L CG  1 
ATOM   5108 C CD  . GLU D 3 166 ? 22.215  2.673   10.905  1.00 40.63  ? 165 GLU L CD  1 
ATOM   5109 O OE1 . GLU D 3 166 ? 21.500  2.442   11.904  1.00 46.23  ? 165 GLU L OE1 1 
ATOM   5110 O OE2 . GLU D 3 166 ? 22.200  1.960   9.879   1.00 49.80  ? 165 GLU L OE2 1 
ATOM   5111 N N   . GLN D 3 167 ? 20.250  5.999   13.485  1.00 31.49  ? 166 GLN L N   1 
ATOM   5112 C CA  . GLN D 3 167 ? 19.700  6.794   14.574  1.00 33.00  ? 166 GLN L CA  1 
ATOM   5113 C C   . GLN D 3 167 ? 20.791  7.675   15.172  1.00 37.58  ? 166 GLN L C   1 
ATOM   5114 O O   . GLN D 3 167 ? 21.841  7.177   15.590  1.00 40.71  ? 166 GLN L O   1 
ATOM   5115 C CB  . GLN D 3 167 ? 19.094  5.874   15.632  1.00 34.21  ? 166 GLN L CB  1 
ATOM   5116 C CG  . GLN D 3 167 ? 18.105  6.551   16.559  1.00 39.30  ? 166 GLN L CG  1 
ATOM   5117 C CD  . GLN D 3 167 ? 17.338  5.559   17.408  1.00 38.89  ? 166 GLN L CD  1 
ATOM   5118 O OE1 . GLN D 3 167 ? 17.711  4.390   17.505  1.00 35.07  ? 166 GLN L OE1 1 
ATOM   5119 N NE2 . GLN D 3 167 ? 16.249  6.015   18.016  1.00 36.40  ? 166 GLN L NE2 1 
ATOM   5120 N N   . ASP D 3 168 ? 20.545  8.985   15.191  1.00 37.33  ? 167 ASP L N   1 
ATOM   5121 C CA  . ASP D 3 168 ? 21.562  9.939   15.615  1.00 37.12  ? 167 ASP L CA  1 
ATOM   5122 C C   . ASP D 3 168 ? 22.000  9.668   17.049  1.00 37.93  ? 167 ASP L C   1 
ATOM   5123 O O   . ASP D 3 168 ? 21.179  9.396   17.929  1.00 38.31  ? 167 ASP L O   1 
ATOM   5124 C CB  . ASP D 3 168 ? 21.029  11.366  15.484  1.00 38.10  ? 167 ASP L CB  1 
ATOM   5125 C CG  . ASP D 3 168 ? 22.084  12.412  15.786  1.00 44.60  ? 167 ASP L CG  1 
ATOM   5126 O OD1 . ASP D 3 168 ? 22.941  12.665  14.913  1.00 45.88  ? 167 ASP L OD1 1 
ATOM   5127 O OD2 . ASP D 3 168 ? 22.055  12.986  16.895  1.00 42.15  ? 167 ASP L OD2 1 
ATOM   5128 N N   . SER D 3 169 ? 23.313  9.737   17.278  1.00 39.69  ? 168 SER L N   1 
ATOM   5129 C CA  . SER D 3 169 ? 23.862  9.411   18.588  1.00 42.69  ? 168 SER L CA  1 
ATOM   5130 C C   . SER D 3 169 ? 23.500  10.438  19.654  1.00 42.02  ? 168 SER L C   1 
ATOM   5131 O O   . SER D 3 169 ? 23.633  10.141  20.847  1.00 47.93  ? 168 SER L O   1 
ATOM   5132 C CB  . SER D 3 169 ? 25.383  9.278   18.499  1.00 41.68  ? 168 SER L CB  1 
ATOM   5133 O OG  . SER D 3 169 ? 25.973  10.487  18.056  1.00 50.86  ? 168 SER L OG  1 
ATOM   5134 N N   . LYS D 3 170 ? 23.046  11.630  19.262  1.00 47.55  ? 169 LYS L N   1 
ATOM   5135 C CA  . LYS D 3 170 ? 22.727  12.684  20.219  1.00 47.94  ? 169 LYS L CA  1 
ATOM   5136 C C   . LYS D 3 170 ? 21.231  12.775  20.500  1.00 49.61  ? 169 LYS L C   1 
ATOM   5137 O O   . LYS D 3 170 ? 20.810  12.667  21.655  1.00 56.37  ? 169 LYS L O   1 
ATOM   5138 C CB  . LYS D 3 170 ? 23.260  14.034  19.720  1.00 52.01  ? 169 LYS L CB  1 
ATOM   5139 C CG  . LYS D 3 170 ? 24.769  14.087  19.509  1.00 55.82  ? 169 LYS L CG  1 
ATOM   5140 C CD  . LYS D 3 170 ? 25.445  14.976  20.547  1.00 70.44  ? 169 LYS L CD  1 
ATOM   5141 C CE  . LYS D 3 170 ? 26.877  15.310  20.149  1.00 74.17  ? 169 LYS L CE  1 
ATOM   5142 N NZ  . LYS D 3 170 ? 27.567  16.155  21.165  1.00 77.69  ? 169 LYS L NZ  1 
ATOM   5143 N N   . ASP D 3 171 ? 20.412  12.962  19.466  1.00 44.96  ? 170 ASP L N   1 
ATOM   5144 C CA  . ASP D 3 171 ? 18.980  13.160  19.651  1.00 44.46  ? 170 ASP L CA  1 
ATOM   5145 C C   . ASP D 3 171 ? 18.134  11.970  19.218  1.00 39.53  ? 170 ASP L C   1 
ATOM   5146 O O   . ASP D 3 171 ? 16.906  12.039  19.321  1.00 41.94  ? 170 ASP L O   1 
ATOM   5147 C CB  . ASP D 3 171 ? 18.517  14.431  18.920  1.00 42.15  ? 170 ASP L CB  1 
ATOM   5148 C CG  . ASP D 3 171 ? 18.737  14.373  17.414  1.00 40.99  ? 170 ASP L CG  1 
ATOM   5149 O OD1 . ASP D 3 171 ? 18.923  13.273  16.855  1.00 39.49  ? 170 ASP L OD1 1 
ATOM   5150 O OD2 . ASP D 3 171 ? 18.721  15.449  16.781  1.00 45.92  ? 170 ASP L OD2 1 
ATOM   5151 N N   . SER D 3 172 ? 18.750  10.896  18.721  1.00 38.87  ? 171 SER L N   1 
ATOM   5152 C CA  . SER D 3 172 ? 18.065  9.648   18.382  1.00 38.35  ? 171 SER L CA  1 
ATOM   5153 C C   . SER D 3 172 ? 17.062  9.804   17.242  1.00 38.08  ? 171 SER L C   1 
ATOM   5154 O O   . SER D 3 172 ? 16.122  9.010   17.130  1.00 36.03  ? 171 SER L O   1 
ATOM   5155 C CB  . SER D 3 172 ? 17.375  9.038   19.608  1.00 33.69  ? 171 SER L CB  1 
ATOM   5156 O OG  . SER D 3 172 ? 18.328  8.577   20.548  1.00 38.06  ? 171 SER L OG  1 
ATOM   5157 N N   . THR D 3 173 ? 17.226  10.810  16.392  1.00 35.66  ? 172 THR L N   1 
ATOM   5158 C CA  . THR D 3 173 ? 16.319  10.987  15.269  1.00 32.27  ? 172 THR L CA  1 
ATOM   5159 C C   . THR D 3 173 ? 16.886  10.337  14.009  1.00 36.67  ? 172 THR L C   1 
ATOM   5160 O O   . THR D 3 173 ? 18.044  9.919   13.954  1.00 37.92  ? 172 THR L O   1 
ATOM   5161 C CB  . THR D 3 173 ? 16.049  12.470  15.015  1.00 33.26  ? 172 THR L CB  1 
ATOM   5162 O OG1 . THR D 3 173 ? 17.257  13.115  14.596  1.00 31.64  ? 172 THR L OG1 1 
ATOM   5163 C CG2 . THR D 3 173 ? 15.526  13.142  16.273  1.00 32.30  ? 172 THR L CG2 1 
ATOM   5164 N N   . TYR D 3 174 ? 16.041  10.250  12.987  1.00 29.08  ? 173 TYR L N   1 
ATOM   5165 C CA  . TYR D 3 174 ? 16.441  9.792   11.667  1.00 32.06  ? 173 TYR L CA  1 
ATOM   5166 C C   . TYR D 3 174 ? 16.394  10.948  10.678  1.00 31.74  ? 173 TYR L C   1 
ATOM   5167 O O   . TYR D 3 174 ? 15.712  11.954  10.893  1.00 31.05  ? 173 TYR L O   1 
ATOM   5168 C CB  . TYR D 3 174 ? 15.531  8.663   11.169  1.00 28.93  ? 173 TYR L CB  1 
ATOM   5169 C CG  . TYR D 3 174 ? 15.648  7.372   11.943  1.00 33.24  ? 173 TYR L CG  1 
ATOM   5170 C CD1 . TYR D 3 174 ? 16.605  6.424   11.609  1.00 31.10  ? 173 TYR L CD1 1 
ATOM   5171 C CD2 . TYR D 3 174 ? 14.791  7.093   12.997  1.00 28.35  ? 173 TYR L CD2 1 
ATOM   5172 C CE1 . TYR D 3 174 ? 16.711  5.239   12.312  1.00 31.27  ? 173 TYR L CE1 1 
ATOM   5173 C CE2 . TYR D 3 174 ? 14.888  5.911   13.704  1.00 30.98  ? 173 TYR L CE2 1 
ATOM   5174 C CZ  . TYR D 3 174 ? 15.850  4.988   13.357  1.00 37.26  ? 173 TYR L CZ  1 
ATOM   5175 O OH  . TYR D 3 174 ? 15.948  3.810   14.061  1.00 39.82  ? 173 TYR L OH  1 
ATOM   5176 N N   . SER D 3 175 ? 17.131  10.788  9.584   1.00 29.79  ? 174 SER L N   1 
ATOM   5177 C CA  . SER D 3 175 ? 17.072  11.698  8.451   1.00 35.66  ? 174 SER L CA  1 
ATOM   5178 C C   . SER D 3 175 ? 17.011  10.872  7.176   1.00 31.40  ? 174 SER L C   1 
ATOM   5179 O O   . SER D 3 175 ? 17.640  9.814   7.084   1.00 32.61  ? 174 SER L O   1 
ATOM   5180 C CB  . SER D 3 175 ? 18.278  12.643  8.422   1.00 32.19  ? 174 SER L CB  1 
ATOM   5181 O OG  . SER D 3 175 ? 18.178  13.624  9.440   1.00 36.84  ? 174 SER L OG  1 
ATOM   5182 N N   . LEU D 3 176 ? 16.261  11.361  6.192   1.00 31.14  ? 175 LEU L N   1 
ATOM   5183 C CA  . LEU D 3 176 ? 16.032  10.634  4.952   1.00 36.73  ? 175 LEU L CA  1 
ATOM   5184 C C   . LEU D 3 176 ? 16.245  11.560  3.763   1.00 34.65  ? 175 LEU L C   1 
ATOM   5185 O O   . LEU D 3 176 ? 15.865  12.733  3.799   1.00 32.90  ? 175 LEU L O   1 
ATOM   5186 C CB  . LEU D 3 176 ? 14.619  10.030  4.928   1.00 33.97  ? 175 LEU L CB  1 
ATOM   5187 C CG  . LEU D 3 176 ? 14.260  9.045   3.814   1.00 41.47  ? 175 LEU L CG  1 
ATOM   5188 C CD1 . LEU D 3 176 ? 13.271  8.019   4.337   1.00 34.18  ? 175 LEU L CD1 1 
ATOM   5189 C CD2 . LEU D 3 176 ? 13.673  9.767   2.612   1.00 40.19  ? 175 LEU L CD2 1 
ATOM   5190 N N   . SER D 3 177 ? 16.876  11.032  2.718   1.00 30.41  ? 176 SER L N   1 
ATOM   5191 C CA  . SER D 3 177 ? 17.117  11.768  1.486   1.00 34.60  ? 176 SER L CA  1 
ATOM   5192 C C   . SER D 3 177 ? 16.561  10.968  0.320   1.00 36.90  ? 176 SER L C   1 
ATOM   5193 O O   . SER D 3 177 ? 16.895  9.791   0.159   1.00 38.26  ? 176 SER L O   1 
ATOM   5194 C CB  . SER D 3 177 ? 18.613  12.036  1.285   1.00 38.37  ? 176 SER L CB  1 
ATOM   5195 O OG  . SER D 3 177 ? 18.848  12.711  0.061   1.00 48.19  ? 176 SER L OG  1 
ATOM   5196 N N   . SER D 3 178 ? 15.722  11.603  -0.493  1.00 36.09  ? 177 SER L N   1 
ATOM   5197 C CA  . SER D 3 178 ? 15.125  10.969  -1.660  1.00 34.42  ? 177 SER L CA  1 
ATOM   5198 C C   . SER D 3 178 ? 15.540  11.739  -2.903  1.00 36.83  ? 177 SER L C   1 
ATOM   5199 O O   . SER D 3 178 ? 15.440  12.967  -2.939  1.00 37.41  ? 177 SER L O   1 
ATOM   5200 C CB  . SER D 3 178 ? 13.599  10.922  -1.543  1.00 32.62  ? 177 SER L CB  1 
ATOM   5201 O OG  . SER D 3 178 ? 13.019  10.302  -2.678  1.00 38.03  ? 177 SER L OG  1 
ATOM   5202 N N   . THR D 3 179 ? 16.003  11.021  -3.920  1.00 34.69  ? 178 THR L N   1 
ATOM   5203 C CA  . THR D 3 179 ? 16.466  11.620  -5.164  1.00 34.04  ? 178 THR L CA  1 
ATOM   5204 C C   . THR D 3 179 ? 15.588  11.130  -6.304  1.00 36.76  ? 178 THR L C   1 
ATOM   5205 O O   . THR D 3 179 ? 15.475  9.919   -6.532  1.00 34.50  ? 178 THR L O   1 
ATOM   5206 C CB  . THR D 3 179 ? 17.933  11.277  -5.431  1.00 39.34  ? 178 THR L CB  1 
ATOM   5207 O OG1 . THR D 3 179 ? 18.743  11.774  -4.359  1.00 41.20  ? 178 THR L OG1 1 
ATOM   5208 C CG2 . THR D 3 179 ? 18.395  11.900  -6.738  1.00 39.35  ? 178 THR L CG2 1 
ATOM   5209 N N   . LEU D 3 180 ? 14.950  12.073  -6.993  1.00 35.67  ? 179 LEU L N   1 
ATOM   5210 C CA  . LEU D 3 180 ? 14.228  11.818  -8.230  1.00 35.12  ? 179 LEU L CA  1 
ATOM   5211 C C   . LEU D 3 180 ? 15.148  12.186  -9.388  1.00 33.85  ? 179 LEU L C   1 
ATOM   5212 O O   . LEU D 3 180 ? 15.606  13.330  -9.480  1.00 31.68  ? 179 LEU L O   1 
ATOM   5213 C CB  . LEU D 3 180 ? 12.938  12.636  -8.285  1.00 32.13  ? 179 LEU L CB  1 
ATOM   5214 C CG  . LEU D 3 180 ? 12.082  12.512  -9.546  1.00 37.56  ? 179 LEU L CG  1 
ATOM   5215 C CD1 . LEU D 3 180 ? 11.279  11.223  -9.513  1.00 37.01  ? 179 LEU L CD1 1 
ATOM   5216 C CD2 . LEU D 3 180 ? 11.173  13.720  -9.709  1.00 38.45  ? 179 LEU L CD2 1 
ATOM   5217 N N   . THR D 3 181 ? 15.417  11.225  -10.266 1.00 33.89  ? 180 THR L N   1 
ATOM   5218 C CA  . THR D 3 181 ? 16.354  11.416  -11.363 1.00 37.10  ? 180 THR L CA  1 
ATOM   5219 C C   . THR D 3 181 ? 15.607  11.337  -12.684 1.00 40.51  ? 180 THR L C   1 
ATOM   5220 O O   . THR D 3 181 ? 14.870  10.377  -12.930 1.00 36.97  ? 180 THR L O   1 
ATOM   5221 C CB  . THR D 3 181 ? 17.475  10.374  -11.325 1.00 34.93  ? 180 THR L CB  1 
ATOM   5222 O OG1 . THR D 3 181 ? 18.149  10.443  -10.062 1.00 40.07  ? 180 THR L OG1 1 
ATOM   5223 C CG2 . THR D 3 181 ? 18.477  10.631  -12.439 1.00 37.17  ? 180 THR L CG2 1 
ATOM   5224 N N   . LEU D 3 182 ? 15.799  12.347  -13.528 1.00 45.66  ? 181 LEU L N   1 
ATOM   5225 C CA  . LEU D 3 182 ? 15.172  12.400  -14.837 1.00 41.13  ? 181 LEU L CA  1 
ATOM   5226 C C   . LEU D 3 182 ? 16.207  12.808  -15.875 1.00 42.07  ? 181 LEU L C   1 
ATOM   5227 O O   . LEU D 3 182 ? 17.258  13.367  -15.550 1.00 37.57  ? 181 LEU L O   1 
ATOM   5228 C CB  . LEU D 3 182 ? 14.003  13.397  -14.864 1.00 45.79  ? 181 LEU L CB  1 
ATOM   5229 C CG  . LEU D 3 182 ? 12.935  13.313  -13.771 1.00 41.21  ? 181 LEU L CG  1 
ATOM   5230 C CD1 . LEU D 3 182 ? 11.954  14.472  -13.894 1.00 44.43  ? 181 LEU L CD1 1 
ATOM   5231 C CD2 . LEU D 3 182 ? 12.205  11.983  -13.820 1.00 47.89  ? 181 LEU L CD2 1 
ATOM   5232 N N   . SER D 3 183 ? 15.911  12.500  -17.133 1.00 40.16  ? 182 SER L N   1 
ATOM   5233 C CA  . SER D 3 183 ? 16.668  13.094  -18.222 1.00 47.14  ? 182 SER L CA  1 
ATOM   5234 C C   . SER D 3 183 ? 16.340  14.579  -18.309 1.00 45.69  ? 182 SER L C   1 
ATOM   5235 O O   . SER D 3 183 ? 15.272  15.025  -17.881 1.00 39.18  ? 182 SER L O   1 
ATOM   5236 C CB  . SER D 3 183 ? 16.356  12.400  -19.548 1.00 43.31  ? 182 SER L CB  1 
ATOM   5237 O OG  . SER D 3 183 ? 14.988  12.532  -19.889 1.00 47.91  ? 182 SER L OG  1 
ATOM   5238 N N   . LYS D 3 184 ? 17.278  15.351  -18.859 1.00 47.64  ? 183 LYS L N   1 
ATOM   5239 C CA  . LYS D 3 184 ? 17.056  16.787  -18.994 1.00 49.37  ? 183 LYS L CA  1 
ATOM   5240 C C   . LYS D 3 184 ? 15.820  17.087  -19.837 1.00 52.84  ? 183 LYS L C   1 
ATOM   5241 O O   . LYS D 3 184 ? 15.091  18.045  -19.559 1.00 53.15  ? 183 LYS L O   1 
ATOM   5242 C CB  . LYS D 3 184 ? 18.296  17.458  -19.583 1.00 49.10  ? 183 LYS L CB  1 
ATOM   5243 C CG  . LYS D 3 184 ? 18.217  18.974  -19.608 1.00 53.89  ? 183 LYS L CG  1 
ATOM   5244 C CD  . LYS D 3 184 ? 19.379  19.562  -20.380 1.00 58.17  ? 183 LYS L CD  1 
ATOM   5245 C CE  . LYS D 3 184 ? 19.466  18.975  -21.777 1.00 55.39  ? 183 LYS L CE  1 
ATOM   5246 N NZ  . LYS D 3 184 ? 20.646  19.498  -22.517 1.00 61.08  ? 183 LYS L NZ  1 
ATOM   5247 N N   . ALA D 3 185 ? 15.568  16.281  -20.872 1.00 47.41  ? 184 ALA L N   1 
ATOM   5248 C CA  . ALA D 3 185 ? 14.389  16.494  -21.710 1.00 52.61  ? 184 ALA L CA  1 
ATOM   5249 C C   . ALA D 3 185 ? 13.099  16.249  -20.931 1.00 53.46  ? 184 ALA L C   1 
ATOM   5250 O O   . ALA D 3 185 ? 12.198  17.101  -20.913 1.00 53.31  ? 184 ALA L O   1 
ATOM   5251 C CB  . ALA D 3 185 ? 14.458  15.592  -22.944 1.00 52.17  ? 184 ALA L CB  1 
ATOM   5252 N N   . ASP D 3 186 ? 12.996  15.088  -20.276 1.00 51.92  ? 185 ASP L N   1 
ATOM   5253 C CA  . ASP D 3 186 ? 11.837  14.800  -19.438 1.00 53.05  ? 185 ASP L CA  1 
ATOM   5254 C C   . ASP D 3 186 ? 11.700  15.815  -18.314 1.00 49.11  ? 185 ASP L C   1 
ATOM   5255 O O   . ASP D 3 186 ? 10.580  16.126  -17.892 1.00 58.24  ? 185 ASP L O   1 
ATOM   5256 C CB  . ASP D 3 186 ? 11.947  13.380  -18.881 1.00 50.19  ? 185 ASP L CB  1 
ATOM   5257 C CG  . ASP D 3 186 ? 11.295  12.349  -19.777 1.00 57.13  ? 185 ASP L CG  1 
ATOM   5258 O OD1 . ASP D 3 186 ? 11.506  11.142  -19.544 1.00 58.64  ? 185 ASP L OD1 1 
ATOM   5259 O OD2 . ASP D 3 186 ? 10.640  12.740  -20.764 1.00 61.67  ? 185 ASP L OD2 1 
ATOM   5260 N N   . TYR D 3 187 ? 12.821  16.349  -17.827 1.00 46.27  ? 186 TYR L N   1 
ATOM   5261 C CA  . TYR D 3 187 ? 12.764  17.399  -16.816 1.00 50.28  ? 186 TYR L CA  1 
ATOM   5262 C C   . TYR D 3 187 ? 12.151  18.674  -17.386 1.00 52.73  ? 186 TYR L C   1 
ATOM   5263 O O   . TYR D 3 187 ? 11.288  19.298  -16.757 1.00 47.31  ? 186 TYR L O   1 
ATOM   5264 C CB  . TYR D 3 187 ? 14.164  17.675  -16.269 1.00 45.87  ? 186 TYR L CB  1 
ATOM   5265 C CG  . TYR D 3 187 ? 14.216  18.821  -15.288 1.00 46.01  ? 186 TYR L CG  1 
ATOM   5266 C CD1 . TYR D 3 187 ? 13.567  18.742  -14.065 1.00 44.95  ? 186 TYR L CD1 1 
ATOM   5267 C CD2 . TYR D 3 187 ? 14.916  19.983  -15.585 1.00 50.84  ? 186 TYR L CD2 1 
ATOM   5268 C CE1 . TYR D 3 187 ? 13.611  19.788  -13.163 1.00 43.85  ? 186 TYR L CE1 1 
ATOM   5269 C CE2 . TYR D 3 187 ? 14.968  21.034  -14.690 1.00 46.33  ? 186 TYR L CE2 1 
ATOM   5270 C CZ  . TYR D 3 187 ? 14.313  20.933  -13.482 1.00 44.08  ? 186 TYR L CZ  1 
ATOM   5271 O OH  . TYR D 3 187 ? 14.360  21.977  -12.586 1.00 43.20  ? 186 TYR L OH  1 
ATOM   5272 N N   . GLU D 3 188 ? 12.586  19.073  -18.583 1.00 51.17  ? 187 GLU L N   1 
ATOM   5273 C CA  . GLU D 3 188 ? 12.090  20.294  -19.202 1.00 52.30  ? 187 GLU L CA  1 
ATOM   5274 C C   . GLU D 3 188 ? 10.684  20.144  -19.760 1.00 50.86  ? 187 GLU L C   1 
ATOM   5275 O O   . GLU D 3 188 ? 10.083  21.150  -20.152 1.00 54.25  ? 187 GLU L O   1 
ATOM   5276 C CB  . GLU D 3 188 ? 13.037  20.734  -20.318 1.00 51.00  ? 187 GLU L CB  1 
ATOM   5277 C CG  . GLU D 3 188 ? 14.364  21.283  -19.828 1.00 52.98  ? 187 GLU L CG  1 
ATOM   5278 C CD  . GLU D 3 188 ? 15.396  21.384  -20.935 1.00 62.08  ? 187 GLU L CD  1 
ATOM   5279 O OE1 . GLU D 3 188 ? 15.160  20.819  -22.023 1.00 60.18  ? 187 GLU L OE1 1 
ATOM   5280 O OE2 . GLU D 3 188 ? 16.442  22.028  -20.715 1.00 67.23  ? 187 GLU L OE2 1 
ATOM   5281 N N   . LYS D 3 189 ? 10.146  18.927  -19.806 1.00 51.27  ? 188 LYS L N   1 
ATOM   5282 C CA  . LYS D 3 189 ? 8.776   18.745  -20.270 1.00 51.09  ? 188 LYS L CA  1 
ATOM   5283 C C   . LYS D 3 189 ? 7.730   19.022  -19.194 1.00 54.93  ? 188 LYS L C   1 
ATOM   5284 O O   . LYS D 3 189 ? 6.536   18.850  -19.465 1.00 56.20  ? 188 LYS L O   1 
ATOM   5285 C CB  . LYS D 3 189 ? 8.592   17.329  -20.826 1.00 55.96  ? 188 LYS L CB  1 
ATOM   5286 C CG  . LYS D 3 189 ? 8.689   17.266  -22.346 1.00 60.05  ? 188 LYS L CG  1 
ATOM   5287 C CD  . LYS D 3 189 ? 9.352   15.980  -22.804 1.00 64.88  ? 188 LYS L CD  1 
ATOM   5288 C CE  . LYS D 3 189 ? 9.827   16.088  -24.243 1.00 68.58  ? 188 LYS L CE  1 
ATOM   5289 N NZ  . LYS D 3 189 ? 11.197  16.665  -24.323 1.00 66.12  ? 188 LYS L NZ  1 
ATOM   5290 N N   . HIS D 3 190 ? 8.128   19.449  -17.994 1.00 54.22  ? 189 HIS L N   1 
ATOM   5291 C CA  . HIS D 3 190 ? 7.187   19.649  -16.899 1.00 49.55  ? 189 HIS L CA  1 
ATOM   5292 C C   . HIS D 3 190 ? 7.563   20.903  -16.118 1.00 45.39  ? 189 HIS L C   1 
ATOM   5293 O O   . HIS D 3 190 ? 8.644   21.473  -16.295 1.00 50.37  ? 189 HIS L O   1 
ATOM   5294 C CB  . HIS D 3 190 ? 7.137   18.422  -15.982 1.00 49.62  ? 189 HIS L CB  1 
ATOM   5295 C CG  . HIS D 3 190 ? 6.767   17.156  -16.691 1.00 50.03  ? 189 HIS L CG  1 
ATOM   5296 N ND1 . HIS D 3 190 ? 7.706   16.283  -17.196 1.00 53.97  ? 189 HIS L ND1 1 
ATOM   5297 C CD2 . HIS D 3 190 ? 5.558   16.626  -16.995 1.00 54.71  ? 189 HIS L CD2 1 
ATOM   5298 C CE1 . HIS D 3 190 ? 7.093   15.265  -17.773 1.00 52.64  ? 189 HIS L CE1 1 
ATOM   5299 N NE2 . HIS D 3 190 ? 5.790   15.449  -17.666 1.00 54.47  ? 189 HIS L NE2 1 
ATOM   5300 N N   . LYS D 3 191 ? 6.654   21.327  -15.234 1.00 44.24  ? 190 LYS L N   1 
ATOM   5301 C CA  . LYS D 3 191 ? 6.759   22.621  -14.564 1.00 45.09  ? 190 LYS L CA  1 
ATOM   5302 C C   . LYS D 3 191 ? 6.897   22.505  -13.051 1.00 42.97  ? 190 LYS L C   1 
ATOM   5303 O O   . LYS D 3 191 ? 7.886   22.992  -12.494 1.00 47.47  ? 190 LYS L O   1 
ATOM   5304 C CB  . LYS D 3 191 ? 5.537   23.476  -14.932 1.00 49.45  ? 190 LYS L CB  1 
ATOM   5305 C CG  . LYS D 3 191 ? 5.373   24.756  -14.124 1.00 54.18  ? 190 LYS L CG  1 
ATOM   5306 C CD  . LYS D 3 191 ? 6.524   25.722  -14.344 1.00 53.67  ? 190 LYS L CD  1 
ATOM   5307 C CE  . LYS D 3 191 ? 6.090   27.156  -14.082 1.00 56.69  ? 190 LYS L CE  1 
ATOM   5308 N NZ  . LYS D 3 191 ? 5.279   27.277  -12.842 1.00 54.09  ? 190 LYS L NZ  1 
ATOM   5309 N N   . VAL D 3 192 ? 5.941   21.883  -12.366 1.00 39.71  ? 191 VAL L N   1 
ATOM   5310 C CA  . VAL D 3 192 ? 5.886   21.893  -10.906 1.00 47.33  ? 191 VAL L CA  1 
ATOM   5311 C C   . VAL D 3 192 ? 6.447   20.577  -10.386 1.00 45.10  ? 191 VAL L C   1 
ATOM   5312 O O   . VAL D 3 192 ? 5.937   19.500  -10.719 1.00 48.60  ? 191 VAL L O   1 
ATOM   5313 C CB  . VAL D 3 192 ? 4.452   22.116  -10.400 1.00 46.33  ? 191 VAL L CB  1 
ATOM   5314 C CG1 . VAL D 3 192 ? 4.399   21.981  -8.885  1.00 44.06  ? 191 VAL L CG1 1 
ATOM   5315 C CG2 . VAL D 3 192 ? 3.940   23.481  -10.839 1.00 43.72  ? 191 VAL L CG2 1 
ATOM   5316 N N   . TYR D 3 193 ? 7.495   20.660  -9.567  1.00 35.73  ? 192 TYR L N   1 
ATOM   5317 C CA  . TYR D 3 193 ? 8.109   19.488  -8.957  1.00 44.83  ? 192 TYR L CA  1 
ATOM   5318 C C   . TYR D 3 193 ? 7.942   19.566  -7.447  1.00 41.06  ? 192 TYR L C   1 
ATOM   5319 O O   . TYR D 3 193 ? 8.350   20.554  -6.829  1.00 44.28  ? 192 TYR L O   1 
ATOM   5320 C CB  . TYR D 3 193 ? 9.589   19.392  -9.329  1.00 40.30  ? 192 TYR L CB  1 
ATOM   5321 C CG  . TYR D 3 193 ? 9.814   19.042  -10.779 1.00 43.44  ? 192 TYR L CG  1 
ATOM   5322 C CD1 . TYR D 3 193 ? 9.777   20.021  -11.761 1.00 42.44  ? 192 TYR L CD1 1 
ATOM   5323 C CD2 . TYR D 3 193 ? 10.058  17.732  -11.167 1.00 41.40  ? 192 TYR L CD2 1 
ATOM   5324 C CE1 . TYR D 3 193 ? 9.977   19.707  -13.089 1.00 41.86  ? 192 TYR L CE1 1 
ATOM   5325 C CE2 . TYR D 3 193 ? 10.261  17.408  -12.493 1.00 45.76  ? 192 TYR L CE2 1 
ATOM   5326 C CZ  . TYR D 3 193 ? 10.220  18.398  -13.449 1.00 44.64  ? 192 TYR L CZ  1 
ATOM   5327 O OH  . TYR D 3 193 ? 10.420  18.083  -14.771 1.00 52.71  ? 192 TYR L OH  1 
ATOM   5328 N N   . ALA D 3 194 ? 7.360   18.524  -6.854  1.00 40.70  ? 193 ALA L N   1 
ATOM   5329 C CA  . ALA D 3 194 ? 7.010   18.547  -5.443  1.00 38.10  ? 193 ALA L CA  1 
ATOM   5330 C C   . ALA D 3 194 ? 7.324   17.205  -4.800  1.00 39.11  ? 193 ALA L C   1 
ATOM   5331 O O   . ALA D 3 194 ? 7.238   16.154  -5.439  1.00 36.38  ? 193 ALA L O   1 
ATOM   5332 C CB  . ALA D 3 194 ? 5.523   18.873  -5.238  1.00 33.46  ? 193 ALA L CB  1 
ATOM   5333 N N   . CYS D 3 195 ? 7.702   17.254  -3.527  1.00 36.86  ? 194 CYS L N   1 
ATOM   5334 C CA  . CYS D 3 195 ? 7.717   16.072  -2.679  1.00 33.55  ? 194 CYS L CA  1 
ATOM   5335 C C   . CYS D 3 195 ? 6.763   16.290  -1.513  1.00 35.09  ? 194 CYS L C   1 
ATOM   5336 O O   . CYS D 3 195 ? 6.779   17.349  -0.870  1.00 38.24  ? 194 CYS L O   1 
ATOM   5337 C CB  . CYS D 3 195 ? 9.129   15.721  -2.190  1.00 40.85  ? 194 CYS L CB  1 
ATOM   5338 S SG  . CYS D 3 195 ? 9.990   16.895  -1.115  1.00 53.60  ? 194 CYS L SG  1 
ATOM   5339 N N   . GLU D 3 196 ? 5.920   15.291  -1.269  1.00 32.14  ? 195 GLU L N   1 
ATOM   5340 C CA  . GLU D 3 196 ? 4.884   15.324  -0.250  1.00 36.64  ? 195 GLU L CA  1 
ATOM   5341 C C   . GLU D 3 196 ? 5.229   14.300  0.820   1.00 37.22  ? 195 GLU L C   1 
ATOM   5342 O O   . GLU D 3 196 ? 5.459   13.125  0.511   1.00 37.52  ? 195 GLU L O   1 
ATOM   5343 C CB  . GLU D 3 196 ? 3.514   15.023  -0.864  1.00 34.92  ? 195 GLU L CB  1 
ATOM   5344 C CG  . GLU D 3 196 ? 2.383   14.863  0.135   1.00 40.08  ? 195 GLU L CG  1 
ATOM   5345 C CD  . GLU D 3 196 ? 1.133   14.283  -0.499  1.00 53.31  ? 195 GLU L CD  1 
ATOM   5346 O OE1 . GLU D 3 196 ? 0.599   14.907  -1.439  1.00 56.97  ? 195 GLU L OE1 1 
ATOM   5347 O OE2 . GLU D 3 196 ? 0.688   13.203  -0.060  1.00 54.18  ? 195 GLU L OE2 1 
ATOM   5348 N N   . VAL D 3 197 ? 5.267   14.748  2.070   1.00 40.02  ? 196 VAL L N   1 
ATOM   5349 C CA  . VAL D 3 197 ? 5.752   13.953  3.190   1.00 31.10  ? 196 VAL L CA  1 
ATOM   5350 C C   . VAL D 3 197 ? 4.607   13.745  4.168   1.00 33.55  ? 196 VAL L C   1 
ATOM   5351 O O   . VAL D 3 197 ? 3.898   14.697  4.517   1.00 36.71  ? 196 VAL L O   1 
ATOM   5352 C CB  . VAL D 3 197 ? 6.947   14.630  3.885   1.00 32.68  ? 196 VAL L CB  1 
ATOM   5353 C CG1 . VAL D 3 197 ? 7.330   13.872  5.146   1.00 31.92  ? 196 VAL L CG1 1 
ATOM   5354 C CG2 . VAL D 3 197 ? 8.128   14.726  2.932   1.00 32.78  ? 196 VAL L CG2 1 
ATOM   5355 N N   . THR D 3 198 ? 4.427   12.498  4.595   1.00 33.41  ? 197 THR L N   1 
ATOM   5356 C CA  . THR D 3 198 ? 3.479   12.138  5.637   1.00 37.22  ? 197 THR L CA  1 
ATOM   5357 C C   . THR D 3 198 ? 4.225   11.507  6.805   1.00 35.49  ? 197 THR L C   1 
ATOM   5358 O O   . THR D 3 198 ? 5.113   10.672  6.605   1.00 33.10  ? 197 THR L O   1 
ATOM   5359 C CB  . THR D 3 198 ? 2.423   11.170  5.097   1.00 34.62  ? 197 THR L CB  1 
ATOM   5360 O OG1 . THR D 3 198 ? 1.767   11.760  3.968   1.00 40.04  ? 197 THR L OG1 1 
ATOM   5361 C CG2 . THR D 3 198 ? 1.390   10.863  6.155   1.00 41.75  ? 197 THR L CG2 1 
ATOM   5362 N N   . HIS D 3 199 ? 3.843   11.896  8.023   1.00 31.28  ? 198 HIS L N   1 
ATOM   5363 C CA  . HIS D 3 199 ? 4.468   11.402  9.245   1.00 31.95  ? 198 HIS L CA  1 
ATOM   5364 C C   . HIS D 3 199 ? 3.463   11.521  10.383  1.00 32.27  ? 198 HIS L C   1 
ATOM   5365 O O   . HIS D 3 199 ? 2.572   12.374  10.349  1.00 34.21  ? 198 HIS L O   1 
ATOM   5366 C CB  . HIS D 3 199 ? 5.752   12.177  9.572   1.00 33.83  ? 198 HIS L CB  1 
ATOM   5367 C CG  . HIS D 3 199 ? 6.518   11.620  10.731  1.00 33.51  ? 198 HIS L CG  1 
ATOM   5368 N ND1 . HIS D 3 199 ? 6.335   12.058  12.024  1.00 32.89  ? 198 HIS L ND1 1 
ATOM   5369 C CD2 . HIS D 3 199 ? 7.475   10.663  10.790  1.00 31.85  ? 198 HIS L CD2 1 
ATOM   5370 C CE1 . HIS D 3 199 ? 7.141   11.392  12.831  1.00 33.94  ? 198 HIS L CE1 1 
ATOM   5371 N NE2 . HIS D 3 199 ? 7.844   10.540  12.107  1.00 32.56  ? 198 HIS L NE2 1 
ATOM   5372 N N   . GLN D 3 200 ? 3.608   10.647  11.387  1.00 31.97  ? 199 GLN L N   1 
ATOM   5373 C CA  . GLN D 3 200 ? 2.651   10.622  12.492  1.00 28.01  ? 199 GLN L CA  1 
ATOM   5374 C C   . GLN D 3 200 ? 2.665   11.902  13.316  1.00 28.92  ? 199 GLN L C   1 
ATOM   5375 O O   . GLN D 3 200 ? 1.667   12.207  13.978  1.00 28.98  ? 199 GLN L O   1 
ATOM   5376 C CB  . GLN D 3 200 ? 2.891   9.400   13.384  1.00 33.18  ? 199 GLN L CB  1 
ATOM   5377 C CG  . GLN D 3 200 ? 2.303   8.114   12.802  1.00 32.39  ? 199 GLN L CG  1 
ATOM   5378 C CD  . GLN D 3 200 ? 2.266   6.959   13.783  1.00 35.16  ? 199 GLN L CD  1 
ATOM   5379 O OE1 . GLN D 3 200 ? 2.981   6.950   14.784  1.00 37.40  ? 199 GLN L OE1 1 
ATOM   5380 N NE2 . GLN D 3 200 ? 1.417   5.975   13.500  1.00 32.78  ? 199 GLN L NE2 1 
ATOM   5381 N N   . GLY D 3 201 ? 3.759   12.654  13.293  1.00 33.56  ? 200 GLY L N   1 
ATOM   5382 C CA  . GLY D 3 201 ? 3.787   13.947  13.942  1.00 29.26  ? 200 GLY L CA  1 
ATOM   5383 C C   . GLY D 3 201 ? 3.179   15.079  13.147  1.00 32.06  ? 200 GLY L C   1 
ATOM   5384 O O   . GLY D 3 201 ? 3.175   16.221  13.615  1.00 38.39  ? 200 GLY L O   1 
ATOM   5385 N N   . LEU D 3 202 ? 2.658   14.797  11.955  1.00 33.07  ? 201 LEU L N   1 
ATOM   5386 C CA  . LEU D 3 202 ? 2.057   15.802  11.089  1.00 31.60  ? 201 LEU L CA  1 
ATOM   5387 C C   . LEU D 3 202 ? 0.556   15.563  11.002  1.00 33.76  ? 201 LEU L C   1 
ATOM   5388 O O   . LEU D 3 202 ? 0.118   14.453  10.683  1.00 30.45  ? 201 LEU L O   1 
ATOM   5389 C CB  . LEU D 3 202 ? 2.677   15.763  9.691   1.00 30.63  ? 201 LEU L CB  1 
ATOM   5390 C CG  . LEU D 3 202 ? 4.165   16.091  9.563   1.00 36.48  ? 201 LEU L CG  1 
ATOM   5391 C CD1 . LEU D 3 202 ? 4.648   15.786  8.157   1.00 33.92  ? 201 LEU L CD1 1 
ATOM   5392 C CD2 . LEU D 3 202 ? 4.432   17.547  9.918   1.00 32.02  ? 201 LEU L CD2 1 
ATOM   5393 N N   . SER D 3 203 ? -0.227  16.606  11.284  1.00 29.99  ? 202 SER L N   1 
ATOM   5394 C CA  . SER D 3 203 ? -1.677  16.488  11.169  1.00 29.30  ? 202 SER L CA  1 
ATOM   5395 C C   . SER D 3 203 ? -2.117  16.387  9.714   1.00 38.46  ? 202 SER L C   1 
ATOM   5396 O O   . SER D 3 203 ? -3.149  15.773  9.422   1.00 34.85  ? 202 SER L O   1 
ATOM   5397 C CB  . SER D 3 203 ? -2.358  17.677  11.847  1.00 38.53  ? 202 SER L CB  1 
ATOM   5398 O OG  . SER D 3 203 ? -2.000  18.896  11.220  1.00 39.06  ? 202 SER L OG  1 
ATOM   5399 N N   . SER D 3 204 ? -1.358  16.976  8.797   1.00 32.29  ? 203 SER L N   1 
ATOM   5400 C CA  . SER D 3 204 ? -1.632  16.922  7.370   1.00 38.96  ? 203 SER L CA  1 
ATOM   5401 C C   . SER D 3 204 ? -0.310  16.826  6.623   1.00 32.76  ? 203 SER L C   1 
ATOM   5402 O O   . SER D 3 204 ? 0.729   17.251  7.144   1.00 33.60  ? 203 SER L O   1 
ATOM   5403 C CB  . SER D 3 204 ? -2.418  18.155  6.895   1.00 35.34  ? 203 SER L CB  1 
ATOM   5404 O OG  . SER D 3 204 ? -1.735  19.356  7.208   1.00 40.85  ? 203 SER L OG  1 
ATOM   5405 N N   . PRO D 3 205 ? -0.312  16.258  5.415   1.00 42.75  ? 204 PRO L N   1 
ATOM   5406 C CA  . PRO D 3 205 ? 0.945   16.117  4.670   1.00 41.71  ? 204 PRO L CA  1 
ATOM   5407 C C   . PRO D 3 205 ? 1.602   17.463  4.406   1.00 37.83  ? 204 PRO L C   1 
ATOM   5408 O O   . PRO D 3 205 ? 0.935   18.483  4.220   1.00 39.15  ? 204 PRO L O   1 
ATOM   5409 C CB  . PRO D 3 205 ? 0.509   15.445  3.363   1.00 34.05  ? 204 PRO L CB  1 
ATOM   5410 C CG  . PRO D 3 205 ? -0.749  14.733  3.709   1.00 35.19  ? 204 PRO L CG  1 
ATOM   5411 C CD  . PRO D 3 205 ? -1.435  15.594  4.730   1.00 35.78  ? 204 PRO L CD  1 
ATOM   5412 N N   . VAL D 3 206 ? 2.932   17.453  4.390   1.00 35.50  ? 205 VAL L N   1 
ATOM   5413 C CA  . VAL D 3 206 ? 3.728   18.645  4.118   1.00 32.79  ? 205 VAL L CA  1 
ATOM   5414 C C   . VAL D 3 206 ? 4.283   18.532  2.706   1.00 36.80  ? 205 VAL L C   1 
ATOM   5415 O O   . VAL D 3 206 ? 4.995   17.574  2.387   1.00 38.89  ? 205 VAL L O   1 
ATOM   5416 C CB  . VAL D 3 206 ? 4.860   18.810  5.143   1.00 30.99  ? 205 VAL L CB  1 
ATOM   5417 C CG1 . VAL D 3 206 ? 5.817   19.906  4.703   1.00 36.70  ? 205 VAL L CG1 1 
ATOM   5418 C CG2 . VAL D 3 206 ? 4.290   19.113  6.519   1.00 33.05  ? 205 VAL L CG2 1 
ATOM   5419 N N   . THR D 3 207 ? 3.969   19.506  1.859   1.00 35.47  ? 206 THR L N   1 
ATOM   5420 C CA  . THR D 3 207 ? 4.407   19.501  0.470   1.00 35.81  ? 206 THR L CA  1 
ATOM   5421 C C   . THR D 3 207 ? 5.425   20.610  0.246   1.00 35.29  ? 206 THR L C   1 
ATOM   5422 O O   . THR D 3 207 ? 5.159   21.775  0.561   1.00 37.95  ? 206 THR L O   1 
ATOM   5423 C CB  . THR D 3 207 ? 3.220   19.680  -0.480  1.00 39.98  ? 206 THR L CB  1 
ATOM   5424 O OG1 . THR D 3 207 ? 2.328   18.566  -0.350  1.00 39.26  ? 206 THR L OG1 1 
ATOM   5425 C CG2 . THR D 3 207 ? 3.702   19.771  -1.920  1.00 34.79  ? 206 THR L CG2 1 
ATOM   5426 N N   . LYS D 3 208 ? 6.584   20.247  -0.299  1.00 36.88  ? 207 LYS L N   1 
ATOM   5427 C CA  . LYS D 3 208 ? 7.587   21.217  -0.721  1.00 36.67  ? 207 LYS L CA  1 
ATOM   5428 C C   . LYS D 3 208 ? 7.771   21.107  -2.226  1.00 38.44  ? 207 LYS L C   1 
ATOM   5429 O O   . LYS D 3 208 ? 8.040   20.018  -2.743  1.00 43.36  ? 207 LYS L O   1 
ATOM   5430 C CB  . LYS D 3 208 ? 8.919   21.005  0.004   1.00 38.67  ? 207 LYS L CB  1 
ATOM   5431 C CG  . LYS D 3 208 ? 8.902   21.397  1.473   1.00 39.07  ? 207 LYS L CG  1 
ATOM   5432 C CD  . LYS D 3 208 ? 8.626   22.886  1.632   1.00 35.50  ? 207 LYS L CD  1 
ATOM   5433 C CE  . LYS D 3 208 ? 8.708   23.323  3.087   1.00 41.70  ? 207 LYS L CE  1 
ATOM   5434 N NZ  . LYS D 3 208 ? 7.699   22.639  3.938   1.00 44.60  ? 207 LYS L NZ  1 
ATOM   5435 N N   . SER D 3 209 ? 7.644   22.235  -2.922  1.00 39.08  ? 208 SER L N   1 
ATOM   5436 C CA  . SER D 3 209 ? 7.598   22.240  -4.376  1.00 40.70  ? 208 SER L CA  1 
ATOM   5437 C C   . SER D 3 209 ? 8.392   23.416  -4.923  1.00 49.41  ? 208 SER L C   1 
ATOM   5438 O O   . SER D 3 209 ? 8.763   24.344  -4.198  1.00 45.17  ? 208 SER L O   1 
ATOM   5439 C CB  . SER D 3 209 ? 6.153   22.306  -4.888  1.00 43.47  ? 208 SER L CB  1 
ATOM   5440 O OG  . SER D 3 209 ? 5.528   23.517  -4.500  1.00 52.69  ? 208 SER L OG  1 
ATOM   5441 N N   . PHE D 3 210 ? 8.650   23.359  -6.227  1.00 50.16  ? 209 PHE L N   1 
ATOM   5442 C CA  . PHE D 3 210 ? 9.277   24.458  -6.944  1.00 49.32  ? 209 PHE L CA  1 
ATOM   5443 C C   . PHE D 3 210 ? 8.837   24.421  -8.401  1.00 49.56  ? 209 PHE L C   1 
ATOM   5444 O O   . PHE D 3 210 ? 8.322   23.413  -8.899  1.00 48.37  ? 209 PHE L O   1 
ATOM   5445 C CB  . PHE D 3 210 ? 10.810  24.416  -6.840  1.00 50.79  ? 209 PHE L CB  1 
ATOM   5446 C CG  . PHE D 3 210 ? 11.447  23.274  -7.584  1.00 52.61  ? 209 PHE L CG  1 
ATOM   5447 C CD1 . PHE D 3 210 ? 11.674  22.063  -6.954  1.00 44.54  ? 209 PHE L CD1 1 
ATOM   5448 C CD2 . PHE D 3 210 ? 11.832  23.417  -8.908  1.00 47.79  ? 209 PHE L CD2 1 
ATOM   5449 C CE1 . PHE D 3 210 ? 12.263  21.014  -7.632  1.00 46.58  ? 209 PHE L CE1 1 
ATOM   5450 C CE2 . PHE D 3 210 ? 12.419  22.371  -9.593  1.00 46.05  ? 209 PHE L CE2 1 
ATOM   5451 C CZ  . PHE D 3 210 ? 12.637  21.169  -8.953  1.00 48.61  ? 209 PHE L CZ  1 
ATOM   5452 N N   . ASN D 3 211 ? 9.039   25.549  -9.074  1.00 54.24  ? 210 ASN L N   1 
ATOM   5453 C CA  . ASN D 3 211 ? 8.770   25.687  -10.498 1.00 50.26  ? 210 ASN L CA  1 
ATOM   5454 C C   . ASN D 3 211 ? 10.091  25.622  -11.253 1.00 46.54  ? 210 ASN L C   1 
ATOM   5455 O O   . ASN D 3 211 ? 11.069  26.262  -10.853 1.00 48.84  ? 210 ASN L O   1 
ATOM   5456 C CB  . ASN D 3 211 ? 8.048   27.005  -10.781 1.00 54.08  ? 210 ASN L CB  1 
ATOM   5457 C CG  . ASN D 3 211 ? 6.694   27.084  -10.094 1.00 50.25  ? 210 ASN L CG  1 
ATOM   5458 O OD1 . ASN D 3 211 ? 5.759   26.370  -10.453 1.00 55.82  ? 210 ASN L OD1 1 
ATOM   5459 N ND2 . ASN D 3 211 ? 6.588   27.953  -9.094  1.00 52.73  ? 210 ASN L ND2 1 
ATOM   5460 N N   . ARG D 3 212 ? 10.120  24.836  -12.334 1.00 49.26  ? 211 ARG L N   1 
ATOM   5461 C CA  . ARG D 3 212 ? 11.376  24.586  -13.037 1.00 48.33  ? 211 ARG L CA  1 
ATOM   5462 C C   . ARG D 3 212 ? 12.005  25.880  -13.542 1.00 57.17  ? 211 ARG L C   1 
ATOM   5463 O O   . ARG D 3 212 ? 13.223  26.067  -13.442 1.00 68.32  ? 211 ARG L O   1 
ATOM   5464 C CB  . ARG D 3 212 ? 11.149  23.617  -14.198 1.00 49.90  ? 211 ARG L CB  1 
ATOM   5465 C CG  . ARG D 3 212 ? 12.367  23.438  -15.092 1.00 53.03  ? 211 ARG L CG  1 
ATOM   5466 C CD  . ARG D 3 212 ? 12.119  22.415  -16.187 1.00 47.89  ? 211 ARG L CD  1 
ATOM   5467 N NE  . ARG D 3 212 ? 10.891  22.680  -16.927 1.00 53.46  ? 211 ARG L NE  1 
ATOM   5468 C CZ  . ARG D 3 212 ? 10.757  23.632  -17.840 1.00 59.30  ? 211 ARG L CZ  1 
ATOM   5469 N NH1 . ARG D 3 212 ? 11.762  24.432  -18.158 1.00 55.75  ? 211 ARG L NH1 1 
ATOM   5470 N NH2 . ARG D 3 212 ? 9.587   23.783  -18.453 1.00 52.06  ? 211 ARG L NH2 1 
ATOM   5471 N N   . GLY D 3 213 ? 11.191  26.786  -14.085 1.00 52.51  ? 212 GLY L N   1 
ATOM   5472 C CA  . GLY D 3 213 ? 11.718  28.029  -14.621 1.00 63.82  ? 212 GLY L CA  1 
ATOM   5473 C C   . GLY D 3 213 ? 12.222  28.994  -13.569 1.00 64.21  ? 212 GLY L C   1 
ATOM   5474 O O   . GLY D 3 213 ? 13.077  29.834  -13.871 1.00 63.84  ? 212 GLY L O   1 
ATOM   5475 N N   . GLU D 3 214 ? 11.719  28.892  -12.343 1.00 58.30  ? 213 GLU L N   1 
ATOM   5476 C CA  . GLU D 3 214 ? 12.086  29.821  -11.282 1.00 62.73  ? 213 GLU L CA  1 
ATOM   5477 C C   . GLU D 3 214 ? 13.308  29.328  -10.513 1.00 61.22  ? 213 GLU L C   1 
ATOM   5478 O O   . GLU D 3 214 ? 14.144  30.121  -10.080 1.00 61.00  ? 213 GLU L O   1 
ATOM   5479 C CB  . GLU D 3 214 ? 10.910  30.027  -10.324 1.00 52.40  ? 213 GLU L CB  1 
ATOM   5480 C CG  . GLU D 3 214 ? 11.112  31.154  -9.327  1.00 60.45  ? 213 GLU L CG  1 
ATOM   5481 C CD  . GLU D 3 214 ? 10.101  31.124  -8.201  1.00 64.00  ? 213 GLU L CD  1 
ATOM   5482 O OE1 . GLU D 3 214 ? 9.268   30.195  -8.171  1.00 56.73  ? 213 GLU L OE1 1 
ATOM   5483 O OE2 . GLU D 3 214 ? 10.141  32.029  -7.342  1.00 60.18  ? 213 GLU L OE2 1 
ATOM   5484 N N   . LEU E 3 4   ? -24.803 17.142  -36.752 1.00 76.76  ? 4   LEU M N   1 
ATOM   5485 C CA  . LEU E 3 4   ? -24.955 16.646  -38.114 1.00 78.50  ? 4   LEU M CA  1 
ATOM   5486 C C   . LEU E 3 4   ? -25.532 15.234  -38.119 1.00 74.03  ? 4   LEU M C   1 
ATOM   5487 O O   . LEU E 3 4   ? -25.008 14.335  -37.458 1.00 81.15  ? 4   LEU M O   1 
ATOM   5488 C CB  . LEU E 3 4   ? -23.612 16.670  -38.844 1.00 75.33  ? 4   LEU M CB  1 
ATOM   5489 C CG  . LEU E 3 4   ? -22.817 17.977  -38.730 1.00 79.63  ? 4   LEU M CG  1 
ATOM   5490 C CD1 . LEU E 3 4   ? -21.363 17.766  -39.133 1.00 78.57  ? 4   LEU M CD1 1 
ATOM   5491 C CD2 . LEU E 3 4   ? -23.461 19.077  -39.562 1.00 79.89  ? 4   LEU M CD2 1 
ATOM   5492 N N   . THR E 3 5   ? -26.615 15.048  -38.869 1.00 74.86  ? 5   THR M N   1 
ATOM   5493 C CA  . THR E 3 5   ? -27.312 13.774  -38.965 1.00 75.46  ? 5   THR M CA  1 
ATOM   5494 C C   . THR E 3 5   ? -27.149 13.253  -40.386 1.00 74.48  ? 5   THR M C   1 
ATOM   5495 O O   . THR E 3 5   ? -27.521 13.934  -41.344 1.00 76.31  ? 5   THR M O   1 
ATOM   5496 C CB  . THR E 3 5   ? -28.791 13.946  -38.618 1.00 74.32  ? 5   THR M CB  1 
ATOM   5497 O OG1 . THR E 3 5   ? -28.922 14.872  -37.533 1.00 71.88  ? 5   THR M OG1 1 
ATOM   5498 C CG2 . THR E 3 5   ? -29.400 12.614  -38.209 1.00 73.58  ? 5   THR M CG2 1 
ATOM   5499 N N   . GLN E 3 6   ? -26.612 12.048  -40.528 1.00 71.15  ? 6   GLN M N   1 
ATOM   5500 C CA  . GLN E 3 6   ? -26.344 11.492  -41.847 1.00 66.89  ? 6   GLN M CA  1 
ATOM   5501 C C   . GLN E 3 6   ? -27.387 10.447  -42.216 1.00 66.22  ? 6   GLN M C   1 
ATOM   5502 O O   . GLN E 3 6   ? -27.796 9.633   -41.381 1.00 73.92  ? 6   GLN M O   1 
ATOM   5503 C CB  . GLN E 3 6   ? -24.941 10.885  -41.917 1.00 64.85  ? 6   GLN M CB  1 
ATOM   5504 C CG  . GLN E 3 6   ? -23.852 11.836  -41.454 1.00 63.38  ? 6   GLN M CG  1 
ATOM   5505 C CD  . GLN E 3 6   ? -22.507 11.527  -42.078 1.00 59.52  ? 6   GLN M CD  1 
ATOM   5506 O OE1 . GLN E 3 6   ? -21.460 11.761  -41.474 1.00 59.04  ? 6   GLN M OE1 1 
ATOM   5507 N NE2 . GLN E 3 6   ? -22.527 11.004  -43.300 1.00 53.06  ? 6   GLN M NE2 1 
ATOM   5508 N N   . THR E 3 7   ? -27.819 10.483  -43.477 1.00 70.18  ? 7   THR M N   1 
ATOM   5509 C CA  . THR E 3 7   ? -28.842 9.588   -43.987 1.00 68.41  ? 7   THR M CA  1 
ATOM   5510 C C   . THR E 3 7   ? -28.415 9.011   -45.330 1.00 66.32  ? 7   THR M C   1 
ATOM   5511 O O   . THR E 3 7   ? -27.910 9.737   -46.200 1.00 75.93  ? 7   THR M O   1 
ATOM   5512 C CB  . THR E 3 7   ? -30.190 10.308  -44.152 1.00 69.77  ? 7   THR M CB  1 
ATOM   5513 O OG1 . THR E 3 7   ? -30.015 11.472  -44.968 1.00 69.82  ? 7   THR M OG1 1 
ATOM   5514 C CG2 . THR E 3 7   ? -30.752 10.718  -42.799 1.00 71.50  ? 7   THR M CG2 1 
ATOM   5515 N N   . PRO E 3 8   ? -28.594 7.702   -45.522 1.00 61.19  ? 8   PRO M N   1 
ATOM   5516 C CA  . PRO E 3 8   ? -29.075 6.727   -44.536 1.00 63.25  ? 8   PRO M CA  1 
ATOM   5517 C C   . PRO E 3 8   ? -27.946 6.335   -43.593 1.00 62.92  ? 8   PRO M C   1 
ATOM   5518 O O   . PRO E 3 8   ? -26.814 6.758   -43.798 1.00 63.89  ? 8   PRO M O   1 
ATOM   5519 C CB  . PRO E 3 8   ? -29.546 5.561   -45.413 1.00 63.93  ? 8   PRO M CB  1 
ATOM   5520 C CG  . PRO E 3 8   ? -28.615 5.609   -46.594 1.00 57.38  ? 8   PRO M CG  1 
ATOM   5521 C CD  . PRO E 3 8   ? -28.352 7.079   -46.836 1.00 57.14  ? 8   PRO M CD  1 
ATOM   5522 N N   . ALA E 3 9   ? -28.205 5.551   -42.546 1.00 61.25  ? 9   ALA M N   1 
ATOM   5523 C CA  . ALA E 3 9   ? -27.104 5.068   -41.721 1.00 60.18  ? 9   ALA M CA  1 
ATOM   5524 C C   . ALA E 3 9   ? -26.250 4.070   -42.493 1.00 57.81  ? 9   ALA M C   1 
ATOM   5525 O O   . ALA E 3 9   ? -25.019 4.074   -42.379 1.00 57.50  ? 9   ALA M O   1 
ATOM   5526 C CB  . ALA E 3 9   ? -27.640 4.443   -40.434 1.00 58.31  ? 9   ALA M CB  1 
ATOM   5527 N N   . ILE E 3 10  ? -26.888 3.214   -43.287 1.00 56.38  ? 10  ILE M N   1 
ATOM   5528 C CA  . ILE E 3 10  ? -26.210 2.232   -44.123 1.00 56.11  ? 10  ILE M CA  1 
ATOM   5529 C C   . ILE E 3 10  ? -26.822 2.304   -45.513 1.00 59.21  ? 10  ILE M C   1 
ATOM   5530 O O   . ILE E 3 10  ? -28.048 2.260   -45.658 1.00 62.15  ? 10  ILE M O   1 
ATOM   5531 C CB  . ILE E 3 10  ? -26.322 0.803   -43.556 1.00 53.71  ? 10  ILE M CB  1 
ATOM   5532 C CG1 . ILE E 3 10  ? -25.658 0.704   -42.180 1.00 57.73  ? 10  ILE M CG1 1 
ATOM   5533 C CG2 . ILE E 3 10  ? -25.710 -0.204  -44.519 1.00 52.24  ? 10  ILE M CG2 1 
ATOM   5534 C CD1 . ILE E 3 10  ? -26.601 0.928   -41.016 1.00 59.24  ? 10  ILE M CD1 1 
ATOM   5535 N N   . MET E 3 11  ? -25.974 2.420   -46.532 1.00 57.56  ? 11  MET M N   1 
ATOM   5536 C CA  . MET E 3 11  ? -26.416 2.476   -47.920 1.00 50.35  ? 11  MET M CA  1 
ATOM   5537 C C   . MET E 3 11  ? -25.886 1.255   -48.656 1.00 52.72  ? 11  MET M C   1 
ATOM   5538 O O   . MET E 3 11  ? -24.675 1.006   -48.665 1.00 59.31  ? 11  MET M O   1 
ATOM   5539 C CB  . MET E 3 11  ? -25.945 3.765   -48.597 1.00 57.93  ? 11  MET M CB  1 
ATOM   5540 C CG  . MET E 3 11  ? -26.227 3.821   -50.091 1.00 58.44  ? 11  MET M CG  1 
ATOM   5541 S SD  . MET E 3 11  ? -27.870 4.433   -50.505 1.00 73.06  ? 11  MET M SD  1 
ATOM   5542 C CE  . MET E 3 11  ? -28.241 3.434   -51.946 1.00 63.13  ? 11  MET M CE  1 
ATOM   5543 N N   . SER E 3 12  ? -26.793 0.499   -49.268 1.00 50.76  ? 12  SER M N   1 
ATOM   5544 C CA  . SER E 3 12  ? -26.455 -0.674  -50.062 1.00 52.55  ? 12  SER M CA  1 
ATOM   5545 C C   . SER E 3 12  ? -26.701 -0.346  -51.528 1.00 60.06  ? 12  SER M C   1 
ATOM   5546 O O   . SER E 3 12  ? -27.825 -0.003  -51.909 1.00 60.90  ? 12  SER M O   1 
ATOM   5547 C CB  . SER E 3 12  ? -27.282 -1.885  -49.631 1.00 52.00  ? 12  SER M CB  1 
ATOM   5548 O OG  . SER E 3 12  ? -27.171 -2.107  -48.236 1.00 54.81  ? 12  SER M OG  1 
ATOM   5549 N N   . ALA E 3 13  ? -25.655 -0.449  -52.344 1.00 59.21  ? 13  ALA M N   1 
ATOM   5550 C CA  . ALA E 3 13  ? -25.738 -0.047  -53.738 1.00 58.65  ? 13  ALA M CA  1 
ATOM   5551 C C   . ALA E 3 13  ? -24.994 -1.037  -54.618 1.00 55.86  ? 13  ALA M C   1 
ATOM   5552 O O   . ALA E 3 13  ? -23.895 -1.487  -54.279 1.00 54.83  ? 13  ALA M O   1 
ATOM   5553 C CB  . ALA E 3 13  ? -25.168 1.358   -53.945 1.00 62.63  ? 13  ALA M CB  1 
ATOM   5554 N N   . SER E 3 14  ? -25.605 -1.365  -55.754 1.00 60.65  ? 14  SER M N   1 
ATOM   5555 C CA  . SER E 3 14  ? -25.000 -2.227  -56.754 1.00 56.62  ? 14  SER M CA  1 
ATOM   5556 C C   . SER E 3 14  ? -24.019 -1.426  -57.612 1.00 64.47  ? 14  SER M C   1 
ATOM   5557 O O   . SER E 3 14  ? -24.183 -0.214  -57.779 1.00 65.03  ? 14  SER M O   1 
ATOM   5558 C CB  . SER E 3 14  ? -26.077 -2.848  -57.639 1.00 60.90  ? 14  SER M CB  1 
ATOM   5559 O OG  . SER E 3 14  ? -27.146 -3.356  -56.860 1.00 53.82  ? 14  SER M OG  1 
ATOM   5560 N N   . PRO E 3 15  ? -22.975 -2.074  -58.149 1.00 67.06  ? 15  PRO M N   1 
ATOM   5561 C CA  . PRO E 3 15  ? -22.033 -1.355  -59.017 1.00 66.08  ? 15  PRO M CA  1 
ATOM   5562 C C   . PRO E 3 15  ? -22.712 -0.766  -60.243 1.00 65.13  ? 15  PRO M C   1 
ATOM   5563 O O   . PRO E 3 15  ? -23.139 -1.504  -61.136 1.00 70.52  ? 15  PRO M O   1 
ATOM   5564 C CB  . PRO E 3 15  ? -21.017 -2.436  -59.397 1.00 67.60  ? 15  PRO M CB  1 
ATOM   5565 C CG  . PRO E 3 15  ? -21.763 -3.720  -59.256 1.00 68.20  ? 15  PRO M CG  1 
ATOM   5566 C CD  . PRO E 3 15  ? -22.676 -3.516  -58.082 1.00 72.00  ? 15  PRO M CD  1 
ATOM   5567 N N   . GLY E 3 16  ? -22.813 0.560   -60.300 1.00 66.23  ? 16  GLY M N   1 
ATOM   5568 C CA  . GLY E 3 16  ? -23.467 1.200   -61.422 1.00 69.81  ? 16  GLY M CA  1 
ATOM   5569 C C   . GLY E 3 16  ? -24.574 2.159   -61.035 1.00 70.16  ? 16  GLY M C   1 
ATOM   5570 O O   . GLY E 3 16  ? -25.018 2.966   -61.858 1.00 72.55  ? 16  GLY M O   1 
ATOM   5571 N N   . GLU E 3 17  ? -25.037 2.080   -59.791 1.00 63.47  ? 17  GLU M N   1 
ATOM   5572 C CA  . GLU E 3 17  ? -26.115 2.942   -59.334 1.00 65.19  ? 17  GLU M CA  1 
ATOM   5573 C C   . GLU E 3 17  ? -25.612 4.353   -59.054 1.00 69.30  ? 17  GLU M C   1 
ATOM   5574 O O   . GLU E 3 17  ? -24.431 4.571   -58.765 1.00 69.55  ? 17  GLU M O   1 
ATOM   5575 C CB  . GLU E 3 17  ? -26.749 2.388   -58.055 1.00 68.34  ? 17  GLU M CB  1 
ATOM   5576 C CG  . GLU E 3 17  ? -27.341 0.996   -58.163 1.00 67.30  ? 17  GLU M CG  1 
ATOM   5577 C CD  . GLU E 3 17  ? -27.960 0.541   -56.853 1.00 69.79  ? 17  GLU M CD  1 
ATOM   5578 O OE1 . GLU E 3 17  ? -28.127 1.387   -55.950 1.00 63.20  ? 17  GLU M OE1 1 
ATOM   5579 O OE2 . GLU E 3 17  ? -28.278 -0.659  -56.725 1.00 70.71  ? 17  GLU M OE2 1 
ATOM   5580 N N   . LYS E 3 18  ? -26.528 5.315   -59.143 1.00 68.43  ? 18  LYS M N   1 
ATOM   5581 C CA  . LYS E 3 18  ? -26.275 6.664   -58.661 1.00 69.60  ? 18  LYS M CA  1 
ATOM   5582 C C   . LYS E 3 18  ? -26.649 6.715   -57.189 1.00 71.54  ? 18  LYS M C   1 
ATOM   5583 O O   . LYS E 3 18  ? -27.753 6.311   -56.811 1.00 73.97  ? 18  LYS M O   1 
ATOM   5584 C CB  . LYS E 3 18  ? -27.090 7.701   -59.432 1.00 70.53  ? 18  LYS M CB  1 
ATOM   5585 C CG  . LYS E 3 18  ? -26.948 9.102   -58.853 1.00 67.64  ? 18  LYS M CG  1 
ATOM   5586 C CD  . LYS E 3 18  ? -27.887 10.098  -59.511 1.00 69.64  ? 18  LYS M CD  1 
ATOM   5587 C CE  . LYS E 3 18  ? -27.719 11.482  -58.899 1.00 77.04  ? 18  LYS M CE  1 
ATOM   5588 N NZ  . LYS E 3 18  ? -28.471 12.524  -59.647 1.00 80.77  ? 18  LYS M NZ  1 
ATOM   5589 N N   . VAL E 3 19  ? -25.735 7.207   -56.360 1.00 62.98  ? 19  VAL M N   1 
ATOM   5590 C CA  . VAL E 3 19  ? -25.917 7.164   -54.915 1.00 62.70  ? 19  VAL M CA  1 
ATOM   5591 C C   . VAL E 3 19  ? -25.756 8.563   -54.342 1.00 64.96  ? 19  VAL M C   1 
ATOM   5592 O O   . VAL E 3 19  ? -24.890 9.329   -54.778 1.00 63.97  ? 19  VAL M O   1 
ATOM   5593 C CB  . VAL E 3 19  ? -24.944 6.164   -54.259 1.00 68.50  ? 19  VAL M CB  1 
ATOM   5594 C CG1 . VAL E 3 19  ? -25.117 6.153   -52.754 1.00 60.04  ? 19  VAL M CG1 1 
ATOM   5595 C CG2 . VAL E 3 19  ? -25.218 4.780   -54.809 1.00 67.09  ? 19  VAL M CG2 1 
ATOM   5596 N N   . THR E 3 20  ? -26.598 8.893   -53.365 1.00 65.99  ? 20  THR M N   1 
ATOM   5597 C CA  . THR E 3 20  ? -26.586 10.204  -52.730 1.00 68.18  ? 20  THR M CA  1 
ATOM   5598 C C   . THR E 3 20  ? -26.692 10.024  -51.224 1.00 69.50  ? 20  THR M C   1 
ATOM   5599 O O   . THR E 3 20  ? -27.668 9.450   -50.732 1.00 72.23  ? 20  THR M O   1 
ATOM   5600 C CB  . THR E 3 20  ? -27.731 11.078  -53.250 1.00 68.78  ? 20  THR M CB  1 
ATOM   5601 O OG1 . THR E 3 20  ? -27.612 11.226  -54.670 1.00 68.80  ? 20  THR M OG1 1 
ATOM   5602 C CG2 . THR E 3 20  ? -27.687 12.452  -52.599 1.00 65.13  ? 20  THR M CG2 1 
ATOM   5603 N N   . LEU E 3 21  ? -25.688 10.510  -50.502 1.00 69.86  ? 21  LEU M N   1 
ATOM   5604 C CA  . LEU E 3 21  ? -25.673 10.500  -49.046 1.00 73.12  ? 21  LEU M CA  1 
ATOM   5605 C C   . LEU E 3 21  ? -25.958 11.915  -48.567 1.00 75.31  ? 21  LEU M C   1 
ATOM   5606 O O   . LEU E 3 21  ? -25.299 12.865  -49.002 1.00 71.36  ? 21  LEU M O   1 
ATOM   5607 C CB  . LEU E 3 21  ? -24.326 10.026  -48.491 1.00 68.22  ? 21  LEU M CB  1 
ATOM   5608 C CG  . LEU E 3 21  ? -23.725 8.643   -48.768 1.00 65.66  ? 21  LEU M CG  1 
ATOM   5609 C CD1 . LEU E 3 21  ? -23.306 8.459   -50.217 1.00 64.62  ? 21  LEU M CD1 1 
ATOM   5610 C CD2 . LEU E 3 21  ? -22.534 8.416   -47.845 1.00 65.65  ? 21  LEU M CD2 1 
ATOM   5611 N N   . THR E 3 22  ? -26.929 12.055  -47.672 1.00 75.33  ? 22  THR M N   1 
ATOM   5612 C CA  . THR E 3 22  ? -27.380 13.362  -47.222 1.00 76.40  ? 22  THR M CA  1 
ATOM   5613 C C   . THR E 3 22  ? -26.857 13.639  -45.819 1.00 74.79  ? 22  THR M C   1 
ATOM   5614 O O   . THR E 3 22  ? -26.818 12.747  -44.967 1.00 75.64  ? 22  THR M O   1 
ATOM   5615 C CB  . THR E 3 22  ? -28.910 13.451  -47.243 1.00 73.09  ? 22  THR M CB  1 
ATOM   5616 O OG1 . THR E 3 22  ? -29.390 13.109  -48.549 1.00 80.00  ? 22  THR M OG1 1 
ATOM   5617 C CG2 . THR E 3 22  ? -29.376 14.860  -46.898 1.00 77.40  ? 22  THR M CG2 1 
ATOM   5618 N N   . CYS E 3 23  ? -26.444 14.880  -45.596 1.00 78.62  ? 23  CYS M N   1 
ATOM   5619 C CA  . CYS E 3 23  ? -26.012 15.368  -44.294 1.00 78.43  ? 23  CYS M CA  1 
ATOM   5620 C C   . CYS E 3 23  ? -26.960 16.506  -43.940 1.00 81.55  ? 23  CYS M C   1 
ATOM   5621 O O   . CYS E 3 23  ? -26.907 17.583  -44.549 1.00 82.85  ? 23  CYS M O   1 
ATOM   5622 C CB  . CYS E 3 23  ? -24.550 15.823  -44.330 1.00 76.36  ? 23  CYS M CB  1 
ATOM   5623 S SG  . CYS E 3 23  ? -23.821 16.365  -42.749 1.00 83.89  ? 23  CYS M SG  1 
ATOM   5624 N N   . SER E 3 24  ? -27.870 16.230  -43.009 1.00 83.04  ? 24  SER M N   1 
ATOM   5625 C CA  . SER E 3 24  ? -28.823 17.201  -42.502 1.00 83.09  ? 24  SER M CA  1 
ATOM   5626 C C   . SER E 3 24  ? -28.244 17.905  -41.284 1.00 78.18  ? 24  SER M C   1 
ATOM   5627 O O   . SER E 3 24  ? -27.580 17.285  -40.449 1.00 81.90  ? 24  SER M O   1 
ATOM   5628 C CB  . SER E 3 24  ? -30.137 16.507  -42.136 1.00 82.79  ? 24  SER M CB  1 
ATOM   5629 O OG  . SER E 3 24  ? -30.982 17.354  -41.378 1.00 86.85  ? 24  SER M OG  1 
ATOM   5630 N N   . ALA E 3 25  ? -28.488 19.205  -41.192 1.00 79.26  ? 25  ALA M N   1 
ATOM   5631 C CA  . ALA E 3 25  ? -27.964 19.988  -40.081 1.00 82.92  ? 25  ALA M CA  1 
ATOM   5632 C C   . ALA E 3 25  ? -29.091 20.612  -39.269 1.00 90.30  ? 25  ALA M C   1 
ATOM   5633 O O   . ALA E 3 25  ? -29.280 21.827  -39.283 1.00 92.63  ? 25  ALA M O   1 
ATOM   5634 C CB  . ALA E 3 25  ? -27.019 21.063  -40.594 1.00 78.98  ? 25  ALA M CB  1 
ATOM   5635 N N   . MET E 3 32  ? -19.928 22.316  -46.345 1.00 79.76  ? 33  MET M N   1 
ATOM   5636 C CA  . MET E 3 32  ? -19.879 20.976  -45.779 1.00 78.82  ? 33  MET M CA  1 
ATOM   5637 C C   . MET E 3 32  ? -18.531 20.339  -46.102 1.00 80.05  ? 33  MET M C   1 
ATOM   5638 O O   . MET E 3 32  ? -17.960 20.607  -47.158 1.00 82.34  ? 33  MET M O   1 
ATOM   5639 C CB  . MET E 3 32  ? -20.996 20.101  -46.350 1.00 80.49  ? 33  MET M CB  1 
ATOM   5640 C CG  . MET E 3 32  ? -21.531 18.989  -45.435 1.00 80.18  ? 33  MET M CG  1 
ATOM   5641 S SD  . MET E 3 32  ? -22.106 19.517  -43.804 1.00 82.64  ? 33  MET M SD  1 
ATOM   5642 C CE  . MET E 3 32  ? -20.654 19.350  -42.783 1.00 72.19  ? 33  MET M CE  1 
ATOM   5643 N N   . HIS E 3 33  ? -18.015 19.491  -45.215 1.00 77.42  ? 34  HIS M N   1 
ATOM   5644 C CA  . HIS E 3 33  ? -16.814 18.731  -45.527 1.00 75.38  ? 34  HIS M CA  1 
ATOM   5645 C C   . HIS E 3 33  ? -17.140 17.245  -45.478 1.00 74.51  ? 34  HIS M C   1 
ATOM   5646 O O   . HIS E 3 33  ? -17.984 16.813  -44.695 1.00 73.12  ? 34  HIS M O   1 
ATOM   5647 C CB  . HIS E 3 33  ? -15.666 19.077  -44.567 1.00 78.22  ? 34  HIS M CB  1 
ATOM   5648 C CG  . HIS E 3 33  ? -15.315 20.535  -44.544 1.00 82.00  ? 34  HIS M CG  1 
ATOM   5649 N ND1 . HIS E 3 33  ? -14.013 20.984  -44.570 1.00 83.44  ? 34  HIS M ND1 1 
ATOM   5650 C CD2 . HIS E 3 33  ? -16.093 21.643  -44.488 1.00 82.69  ? 34  HIS M CD2 1 
ATOM   5651 C CE1 . HIS E 3 33  ? -14.003 22.305  -44.540 1.00 87.62  ? 34  HIS M CE1 1 
ATOM   5652 N NE2 . HIS E 3 33  ? -15.253 22.729  -44.491 1.00 86.95  ? 34  HIS M NE2 1 
ATOM   5653 N N   . TRP E 3 34  ? -16.458 16.459  -46.310 1.00 68.35  ? 35  TRP M N   1 
ATOM   5654 C CA  . TRP E 3 34  ? -16.703 15.026  -46.416 1.00 63.54  ? 35  TRP M CA  1 
ATOM   5655 C C   . TRP E 3 34  ? -15.384 14.272  -46.388 1.00 62.50  ? 35  TRP M C   1 
ATOM   5656 O O   . TRP E 3 34  ? -14.486 14.560  -47.187 1.00 63.92  ? 35  TRP M O   1 
ATOM   5657 C CB  . TRP E 3 34  ? -17.455 14.680  -47.706 1.00 67.66  ? 35  TRP M CB  1 
ATOM   5658 C CG  . TRP E 3 34  ? -18.809 15.296  -47.820 1.00 73.64  ? 35  TRP M CG  1 
ATOM   5659 C CD1 . TRP E 3 34  ? -19.100 16.571  -48.207 1.00 76.56  ? 35  TRP M CD1 1 
ATOM   5660 C CD2 . TRP E 3 34  ? -20.065 14.659  -47.562 1.00 71.02  ? 35  TRP M CD2 1 
ATOM   5661 N NE1 . TRP E 3 34  ? -20.459 16.771  -48.197 1.00 78.76  ? 35  TRP M NE1 1 
ATOM   5662 C CE2 . TRP E 3 34  ? -21.074 15.611  -47.804 1.00 75.27  ? 35  TRP M CE2 1 
ATOM   5663 C CE3 . TRP E 3 34  ? -20.434 13.377  -47.142 1.00 66.59  ? 35  TRP M CE3 1 
ATOM   5664 C CZ2 . TRP E 3 34  ? -22.427 15.322  -47.643 1.00 78.97  ? 35  TRP M CZ2 1 
ATOM   5665 C CZ3 . TRP E 3 34  ? -21.776 13.091  -46.985 1.00 68.32  ? 35  TRP M CZ3 1 
ATOM   5666 C CH2 . TRP E 3 34  ? -22.756 14.059  -47.234 1.00 75.12  ? 35  TRP M CH2 1 
ATOM   5667 N N   . PHE E 3 35  ? -15.303 13.274  -45.510 1.00 63.21  ? 36  PHE M N   1 
ATOM   5668 C CA  . PHE E 3 35  ? -14.140 12.413  -45.362 1.00 59.84  ? 36  PHE M CA  1 
ATOM   5669 C C   . PHE E 3 35  ? -14.527 10.979  -45.687 1.00 57.74  ? 36  PHE M C   1 
ATOM   5670 O O   . PHE E 3 35  ? -15.615 10.523  -45.316 1.00 61.53  ? 36  PHE M O   1 
ATOM   5671 C CB  . PHE E 3 35  ? -13.585 12.462  -43.934 1.00 54.65  ? 36  PHE M CB  1 
ATOM   5672 C CG  . PHE E 3 35  ? -13.238 13.840  -43.462 1.00 60.25  ? 36  PHE M CG  1 
ATOM   5673 C CD1 . PHE E 3 35  ? -14.225 14.692  -43.005 1.00 65.77  ? 36  PHE M CD1 1 
ATOM   5674 C CD2 . PHE E 3 35  ? -11.927 14.284  -43.467 1.00 63.04  ? 36  PHE M CD2 1 
ATOM   5675 C CE1 . PHE E 3 35  ? -13.917 15.958  -42.574 1.00 68.72  ? 36  PHE M CE1 1 
ATOM   5676 C CE2 . PHE E 3 35  ? -11.615 15.557  -43.028 1.00 65.95  ? 36  PHE M CE2 1 
ATOM   5677 C CZ  . PHE E 3 35  ? -12.614 16.392  -42.577 1.00 70.78  ? 36  PHE M CZ  1 
ATOM   5678 N N   . GLN E 3 36  ? -13.632 10.273  -46.371 1.00 53.63  ? 37  GLN M N   1 
ATOM   5679 C CA  . GLN E 3 36  ? -13.781 8.847   -46.619 1.00 54.61  ? 37  GLN M CA  1 
ATOM   5680 C C   . GLN E 3 36  ? -12.854 8.075   -45.693 1.00 55.31  ? 37  GLN M C   1 
ATOM   5681 O O   . GLN E 3 36  ? -11.698 8.459   -45.494 1.00 54.28  ? 37  GLN M O   1 
ATOM   5682 C CB  . GLN E 3 36  ? -13.461 8.490   -48.071 1.00 47.95  ? 37  GLN M CB  1 
ATOM   5683 C CG  . GLN E 3 36  ? -13.625 7.008   -48.377 1.00 45.10  ? 37  GLN M CG  1 
ATOM   5684 C CD  . GLN E 3 36  ? -12.875 6.573   -49.620 1.00 51.06  ? 37  GLN M CD  1 
ATOM   5685 O OE1 . GLN E 3 36  ? -11.644 6.569   -49.646 1.00 54.64  ? 37  GLN M OE1 1 
ATOM   5686 N NE2 . GLN E 3 36  ? -13.614 6.200   -50.658 1.00 56.92  ? 37  GLN M NE2 1 
ATOM   5687 N N   . GLN E 3 37  ? -13.365 6.985   -45.128 1.00 48.91  ? 38  GLN M N   1 
ATOM   5688 C CA  . GLN E 3 37  ? -12.562 6.114   -44.284 1.00 53.25  ? 38  GLN M CA  1 
ATOM   5689 C C   . GLN E 3 37  ? -12.884 4.665   -44.609 1.00 54.18  ? 38  GLN M C   1 
ATOM   5690 O O   . GLN E 3 37  ? -14.050 4.263   -44.586 1.00 53.49  ? 38  GLN M O   1 
ATOM   5691 C CB  . GLN E 3 37  ? -12.814 6.385   -42.796 1.00 53.32  ? 38  GLN M CB  1 
ATOM   5692 C CG  . GLN E 3 37  ? -12.016 5.481   -41.868 1.00 54.13  ? 38  GLN M CG  1 
ATOM   5693 C CD  . GLN E 3 37  ? -12.263 5.779   -40.403 1.00 53.78  ? 38  GLN M CD  1 
ATOM   5694 O OE1 . GLN E 3 37  ? -13.401 5.995   -39.985 1.00 56.83  ? 38  GLN M OE1 1 
ATOM   5695 N NE2 . GLN E 3 37  ? -11.196 5.787   -39.613 1.00 51.55  ? 38  GLN M NE2 1 
ATOM   5696 N N   . LYS E 3 38  ? -11.856 3.891   -44.922 1.00 51.01  ? 39  LYS M N   1 
ATOM   5697 C CA  . LYS E 3 38  ? -11.986 2.446   -45.004 1.00 55.94  ? 39  LYS M CA  1 
ATOM   5698 C C   . LYS E 3 38  ? -11.514 1.830   -43.694 1.00 62.54  ? 39  LYS M C   1 
ATOM   5699 O O   . LYS E 3 38  ? -10.753 2.439   -42.938 1.00 57.55  ? 39  LYS M O   1 
ATOM   5700 C CB  . LYS E 3 38  ? -11.201 1.884   -46.191 1.00 56.54  ? 39  LYS M CB  1 
ATOM   5701 C CG  . LYS E 3 38  ? -11.641 2.464   -47.527 1.00 54.85  ? 39  LYS M CG  1 
ATOM   5702 C CD  . LYS E 3 38  ? -11.128 1.645   -48.701 1.00 57.01  ? 39  LYS M CD  1 
ATOM   5703 C CE  . LYS E 3 38  ? -11.676 2.183   -50.014 1.00 51.82  ? 39  LYS M CE  1 
ATOM   5704 N NZ  . LYS E 3 38  ? -11.305 1.328   -51.173 1.00 57.08  ? 39  LYS M NZ  1 
ATOM   5705 N N   . SER E 3 39  ? -12.004 0.622   -43.424 1.00 63.33  ? 40  SER M N   1 
ATOM   5706 C CA  . SER E 3 39  ? -11.802 -0.029  -42.133 1.00 62.40  ? 40  SER M CA  1 
ATOM   5707 C C   . SER E 3 39  ? -10.337 -0.017  -41.721 1.00 62.16  ? 40  SER M C   1 
ATOM   5708 O O   . SER E 3 39  ? -9.469  -0.494  -42.456 1.00 59.09  ? 40  SER M O   1 
ATOM   5709 C CB  . SER E 3 39  ? -12.323 -1.467  -42.194 1.00 65.13  ? 40  SER M CB  1 
ATOM   5710 O OG  . SER E 3 39  ? -12.215 -2.103  -40.933 1.00 71.13  ? 40  SER M OG  1 
ATOM   5711 N N   . GLY E 3 40  ? -10.065 0.555   -40.547 1.00 61.54  ? 41  GLY M N   1 
ATOM   5712 C CA  . GLY E 3 40  ? -8.743  0.534   -39.960 1.00 62.34  ? 41  GLY M CA  1 
ATOM   5713 C C   . GLY E 3 40  ? -7.810  1.644   -40.395 1.00 60.61  ? 41  GLY M C   1 
ATOM   5714 O O   . GLY E 3 40  ? -6.772  1.841   -39.750 1.00 62.21  ? 41  GLY M O   1 
ATOM   5715 N N   . THR E 3 41  ? -8.141  2.380   -41.450 1.00 60.42  ? 42  THR M N   1 
ATOM   5716 C CA  . THR E 3 41  ? -7.259  3.401   -41.992 1.00 56.93  ? 42  THR M CA  1 
ATOM   5717 C C   . THR E 3 41  ? -7.699  4.789   -41.536 1.00 56.71  ? 42  THR M C   1 
ATOM   5718 O O   . THR E 3 41  ? -8.827  4.993   -41.081 1.00 49.81  ? 42  THR M O   1 
ATOM   5719 C CB  . THR E 3 41  ? -7.235  3.331   -43.523 1.00 53.56  ? 42  THR M CB  1 
ATOM   5720 O OG1 . THR E 3 41  ? -7.366  1.966   -43.940 1.00 64.82  ? 42  THR M OG1 1 
ATOM   5721 C CG2 . THR E 3 41  ? -5.924  3.882   -44.074 1.00 60.63  ? 42  THR M CG2 1 
ATOM   5722 N N   . SER E 3 42  ? -6.784  5.744   -41.666 1.00 52.03  ? 43  SER M N   1 
ATOM   5723 C CA  . SER E 3 42  ? -7.066  7.111   -41.258 1.00 54.04  ? 43  SER M CA  1 
ATOM   5724 C C   . SER E 3 42  ? -8.112  7.727   -42.183 1.00 55.88  ? 43  SER M C   1 
ATOM   5725 O O   . SER E 3 42  ? -8.129  7.437   -43.384 1.00 56.26  ? 43  SER M O   1 
ATOM   5726 C CB  . SER E 3 42  ? -5.791  7.953   -41.290 1.00 57.48  ? 43  SER M CB  1 
ATOM   5727 O OG  . SER E 3 42  ? -4.863  7.521   -40.310 1.00 65.82  ? 43  SER M OG  1 
ATOM   5728 N N   . PRO E 3 43  ? -9.002  8.568   -41.659 1.00 60.63  ? 44  PRO M N   1 
ATOM   5729 C CA  . PRO E 3 43  ? -9.928  9.290   -42.540 1.00 59.53  ? 44  PRO M CA  1 
ATOM   5730 C C   . PRO E 3 43  ? -9.166  10.204  -43.488 1.00 61.07  ? 44  PRO M C   1 
ATOM   5731 O O   . PRO E 3 43  ? -8.173  10.831  -43.114 1.00 60.19  ? 44  PRO M O   1 
ATOM   5732 C CB  . PRO E 3 43  ? -10.801 10.088  -41.564 1.00 55.94  ? 44  PRO M CB  1 
ATOM   5733 C CG  . PRO E 3 43  ? -10.641 9.405   -40.244 1.00 55.06  ? 44  PRO M CG  1 
ATOM   5734 C CD  . PRO E 3 43  ? -9.248  8.856   -40.237 1.00 54.68  ? 44  PRO M CD  1 
ATOM   5735 N N   . LYS E 3 44  ? -9.640  10.277  -44.726 1.00 55.96  ? 45  LYS M N   1 
ATOM   5736 C CA  . LYS E 3 44  ? -9.020  11.096  -45.757 1.00 61.55  ? 45  LYS M CA  1 
ATOM   5737 C C   . LYS E 3 44  ? -10.013 12.156  -46.203 1.00 59.28  ? 45  LYS M C   1 
ATOM   5738 O O   . LYS E 3 44  ? -11.181 11.843  -46.460 1.00 54.15  ? 45  LYS M O   1 
ATOM   5739 C CB  . LYS E 3 44  ? -8.585  10.248  -46.955 1.00 54.64  ? 45  LYS M CB  1 
ATOM   5740 C CG  . LYS E 3 44  ? -8.013  8.893   -46.577 1.00 60.85  ? 45  LYS M CG  1 
ATOM   5741 C CD  . LYS E 3 44  ? -7.611  8.100   -47.808 1.00 65.08  ? 45  LYS M CD  1 
ATOM   5742 C CE  . LYS E 3 44  ? -6.400  7.226   -47.532 1.00 66.58  ? 45  LYS M CE  1 
ATOM   5743 N NZ  . LYS E 3 44  ? -5.937  6.522   -48.758 1.00 67.95  ? 45  LYS M NZ  1 
ATOM   5744 N N   . ARG E 3 45  ? -9.555  13.403  -46.285 1.00 61.03  ? 46  ARG M N   1 
ATOM   5745 C CA  . ARG E 3 45  ? -10.395 14.460  -46.828 1.00 60.98  ? 46  ARG M CA  1 
ATOM   5746 C C   . ARG E 3 45  ? -10.783 14.104  -48.255 1.00 61.68  ? 46  ARG M C   1 
ATOM   5747 O O   . ARG E 3 45  ? -9.919  13.845  -49.098 1.00 58.77  ? 46  ARG M O   1 
ATOM   5748 C CB  . ARG E 3 45  ? -9.666  15.801  -46.786 1.00 65.27  ? 46  ARG M CB  1 
ATOM   5749 C CG  . ARG E 3 45  ? -10.565 16.990  -47.092 1.00 72.61  ? 46  ARG M CG  1 
ATOM   5750 C CD  . ARG E 3 45  ? -9.787  18.293  -47.155 1.00 73.62  ? 46  ARG M CD  1 
ATOM   5751 N NE  . ARG E 3 45  ? -8.834  18.308  -48.259 1.00 81.19  ? 46  ARG M NE  1 
ATOM   5752 C CZ  . ARG E 3 45  ? -8.284  19.406  -48.758 1.00 78.93  ? 46  ARG M CZ  1 
ATOM   5753 N NH1 . ARG E 3 45  ? -8.579  20.604  -48.283 1.00 73.53  ? 46  ARG M NH1 1 
ATOM   5754 N NH2 . ARG E 3 45  ? -7.422  19.299  -49.766 1.00 75.08  ? 46  ARG M NH2 1 
ATOM   5755 N N   . TRP E 3 46  ? -12.085 14.084  -48.523 1.00 56.32  ? 47  TRP M N   1 
ATOM   5756 C CA  . TRP E 3 46  ? -12.613 13.622  -49.799 1.00 55.54  ? 47  TRP M CA  1 
ATOM   5757 C C   . TRP E 3 46  ? -13.281 14.732  -50.593 1.00 66.09  ? 47  TRP M C   1 
ATOM   5758 O O   . TRP E 3 46  ? -12.960 14.928  -51.769 1.00 61.92  ? 47  TRP M O   1 
ATOM   5759 C CB  . TRP E 3 46  ? -13.605 12.471  -49.567 1.00 52.35  ? 47  TRP M CB  1 
ATOM   5760 C CG  . TRP E 3 46  ? -13.645 11.473  -50.681 1.00 49.66  ? 47  TRP M CG  1 
ATOM   5761 C CD1 . TRP E 3 46  ? -14.693 11.224  -51.518 1.00 55.30  ? 47  TRP M CD1 1 
ATOM   5762 C CD2 . TRP E 3 46  ? -12.589 10.594  -51.087 1.00 46.63  ? 47  TRP M CD2 1 
ATOM   5763 N NE1 . TRP E 3 46  ? -14.358 10.241  -52.416 1.00 55.17  ? 47  TRP M NE1 1 
ATOM   5764 C CE2 . TRP E 3 46  ? -13.071 9.838   -52.174 1.00 54.30  ? 47  TRP M CE2 1 
ATOM   5765 C CE3 . TRP E 3 46  ? -11.284 10.372  -50.637 1.00 48.56  ? 47  TRP M CE3 1 
ATOM   5766 C CZ2 . TRP E 3 46  ? -12.296 8.876   -52.817 1.00 55.83  ? 47  TRP M CZ2 1 
ATOM   5767 C CZ3 . TRP E 3 46  ? -10.515 9.417   -51.277 1.00 49.13  ? 47  TRP M CZ3 1 
ATOM   5768 C CH2 . TRP E 3 46  ? -11.023 8.682   -52.355 1.00 47.16  ? 47  TRP M CH2 1 
ATOM   5769 N N   . ILE E 3 47  ? -14.206 15.469  -49.982 1.00 65.97  ? 48  ILE M N   1 
ATOM   5770 C CA  . ILE E 3 47  ? -14.861 16.590  -50.653 1.00 66.66  ? 48  ILE M CA  1 
ATOM   5771 C C   . ILE E 3 47  ? -14.917 17.754  -49.674 1.00 73.95  ? 48  ILE M C   1 
ATOM   5772 O O   . ILE E 3 47  ? -15.720 17.744  -48.737 1.00 74.03  ? 48  ILE M O   1 
ATOM   5773 C CB  . ILE E 3 47  ? -16.268 16.243  -51.166 1.00 65.90  ? 48  ILE M CB  1 
ATOM   5774 C CG1 . ILE E 3 47  ? -16.212 15.056  -52.129 1.00 66.07  ? 48  ILE M CG1 1 
ATOM   5775 C CG2 . ILE E 3 47  ? -16.895 17.438  -51.860 1.00 73.11  ? 48  ILE M CG2 1 
ATOM   5776 C CD1 . ILE E 3 47  ? -17.566 14.542  -52.541 1.00 64.19  ? 48  ILE M CD1 1 
ATOM   5777 N N   . TYR E 3 48  ? -14.087 18.761  -49.902 1.00 77.55  ? 49  TYR M N   1 
ATOM   5778 C CA  . TYR E 3 48  ? -14.002 19.925  -49.036 1.00 78.97  ? 49  TYR M CA  1 
ATOM   5779 C C   . TYR E 3 48  ? -14.710 21.113  -49.675 1.00 82.17  ? 49  TYR M C   1 
ATOM   5780 O O   . TYR E 3 48  ? -14.850 21.191  -50.898 1.00 79.32  ? 49  TYR M O   1 
ATOM   5781 C CB  . TYR E 3 48  ? -12.538 20.273  -48.731 1.00 79.40  ? 49  TYR M CB  1 
ATOM   5782 C CG  . TYR E 3 48  ? -11.655 20.510  -49.946 1.00 81.97  ? 49  TYR M CG  1 
ATOM   5783 C CD1 . TYR E 3 48  ? -11.394 19.492  -50.859 1.00 74.17  ? 49  TYR M CD1 1 
ATOM   5784 C CD2 . TYR E 3 48  ? -11.059 21.744  -50.163 1.00 84.81  ? 49  TYR M CD2 1 
ATOM   5785 C CE1 . TYR E 3 48  ? -10.588 19.704  -51.960 1.00 79.62  ? 49  TYR M CE1 1 
ATOM   5786 C CE2 . TYR E 3 48  ? -10.245 21.963  -51.261 1.00 79.32  ? 49  TYR M CE2 1 
ATOM   5787 C CZ  . TYR E 3 48  ? -10.014 20.940  -52.155 1.00 79.50  ? 49  TYR M CZ  1 
ATOM   5788 O OH  . TYR E 3 48  ? -9.207  21.148  -53.251 1.00 83.87  ? 49  TYR M OH  1 
ATOM   5789 N N   . ASP E 3 49  ? -15.157 22.037  -48.825 1.00 80.31  ? 50  ASP M N   1 
ATOM   5790 C CA  . ASP E 3 49  ? -15.894 23.225  -49.254 1.00 81.07  ? 50  ASP M CA  1 
ATOM   5791 C C   . ASP E 3 49  ? -17.084 22.847  -50.136 1.00 81.33  ? 50  ASP M C   1 
ATOM   5792 O O   . ASP E 3 49  ? -17.233 23.320  -51.265 1.00 86.42  ? 50  ASP M O   1 
ATOM   5793 C CB  . ASP E 3 49  ? -14.968 24.210  -49.965 1.00 86.38  ? 50  ASP M CB  1 
ATOM   5794 C CG  . ASP E 3 49  ? -13.805 24.643  -49.095 1.00 88.39  ? 50  ASP M CG  1 
ATOM   5795 O OD1 . ASP E 3 49  ? -13.962 24.656  -47.855 1.00 85.93  ? 50  ASP M OD1 1 
ATOM   5796 O OD2 . ASP E 3 49  ? -12.732 24.965  -49.648 1.00 93.49  ? 50  ASP M OD2 1 
ATOM   5797 N N   . THR E 3 50  ? -17.918 21.947  -49.607 1.00 82.64  ? 51  THR M N   1 
ATOM   5798 C CA  . THR E 3 50  ? -19.185 21.528  -50.205 1.00 82.47  ? 51  THR M CA  1 
ATOM   5799 C C   . THR E 3 50  ? -19.005 20.711  -51.481 1.00 78.60  ? 51  THR M C   1 
ATOM   5800 O O   . THR E 3 50  ? -19.581 19.625  -51.602 1.00 73.09  ? 51  THR M O   1 
ATOM   5801 C CB  . THR E 3 50  ? -20.082 22.741  -50.485 1.00 82.78  ? 51  THR M CB  1 
ATOM   5802 O OG1 . THR E 3 50  ? -20.333 23.445  -49.262 1.00 76.45  ? 51  THR M OG1 1 
ATOM   5803 C CG2 . THR E 3 50  ? -21.406 22.299  -51.090 1.00 82.57  ? 51  THR M CG2 1 
ATOM   5804 N N   . SER E 3 51  ? -18.213 21.204  -52.438 1.00 81.25  ? 52  SER M N   1 
ATOM   5805 C CA  . SER E 3 51  ? -18.158 20.570  -53.749 1.00 77.03  ? 52  SER M CA  1 
ATOM   5806 C C   . SER E 3 51  ? -16.758 20.390  -54.322 1.00 73.95  ? 52  SER M C   1 
ATOM   5807 O O   . SER E 3 51  ? -16.633 19.798  -55.399 1.00 78.19  ? 52  SER M O   1 
ATOM   5808 C CB  . SER E 3 51  ? -19.006 21.367  -54.755 1.00 83.77  ? 52  SER M CB  1 
ATOM   5809 O OG  . SER E 3 51  ? -18.679 22.744  -54.719 1.00 86.15  ? 52  SER M OG  1 
ATOM   5810 N N   . LYS E 3 52  ? -15.710 20.867  -53.657 1.00 72.74  ? 53  LYS M N   1 
ATOM   5811 C CA  . LYS E 3 52  ? -14.363 20.752  -54.202 1.00 75.25  ? 53  LYS M CA  1 
ATOM   5812 C C   . LYS E 3 52  ? -13.811 19.354  -53.951 1.00 74.81  ? 53  LYS M C   1 
ATOM   5813 O O   . LYS E 3 52  ? -13.870 18.844  -52.829 1.00 77.84  ? 53  LYS M O   1 
ATOM   5814 C CB  . LYS E 3 52  ? -13.447 21.809  -53.588 1.00 81.84  ? 53  LYS M CB  1 
ATOM   5815 C CG  . LYS E 3 52  ? -13.983 23.226  -53.712 1.00 85.53  ? 53  LYS M CG  1 
ATOM   5816 C CD  . LYS E 3 52  ? -13.074 24.233  -53.028 1.00 89.66  ? 53  LYS M CD  1 
ATOM   5817 C CE  . LYS E 3 52  ? -13.645 25.638  -53.125 1.00 90.37  ? 53  LYS M CE  1 
ATOM   5818 N NZ  . LYS E 3 52  ? -12.781 26.641  -52.443 1.00 89.22  ? 53  LYS M NZ  1 
ATOM   5819 N N   . LEU E 3 53  ? -13.274 18.739  -55.002 1.00 71.10  ? 54  LEU M N   1 
ATOM   5820 C CA  . LEU E 3 53  ? -12.736 17.387  -54.926 1.00 71.79  ? 54  LEU M CA  1 
ATOM   5821 C C   . LEU E 3 53  ? -11.283 17.425  -54.470 1.00 71.36  ? 54  LEU M C   1 
ATOM   5822 O O   . LEU E 3 53  ? -10.481 18.204  -54.994 1.00 71.94  ? 54  LEU M O   1 
ATOM   5823 C CB  . LEU E 3 53  ? -12.843 16.691  -56.284 1.00 69.89  ? 54  LEU M CB  1 
ATOM   5824 C CG  . LEU E 3 53  ? -14.251 16.358  -56.782 1.00 75.05  ? 54  LEU M CG  1 
ATOM   5825 C CD1 . LEU E 3 53  ? -14.189 15.560  -58.077 1.00 72.06  ? 54  LEU M CD1 1 
ATOM   5826 C CD2 . LEU E 3 53  ? -15.034 15.601  -55.719 1.00 75.64  ? 54  LEU M CD2 1 
ATOM   5827 N N   . ALA E 3 54  ? -10.951 16.579  -53.498 1.00 72.48  ? 55  ALA M N   1 
ATOM   5828 C CA  . ALA E 3 54  ? -9.589  16.497  -52.997 1.00 73.62  ? 55  ALA M CA  1 
ATOM   5829 C C   . ALA E 3 54  ? -8.686  15.779  -54.000 1.00 72.42  ? 55  ALA M C   1 
ATOM   5830 O O   . ALA E 3 54  ? -9.137  15.222  -55.005 1.00 70.79  ? 55  ALA M O   1 
ATOM   5831 C CB  . ALA E 3 54  ? -9.558  15.785  -51.646 1.00 69.32  ? 55  ALA M CB  1 
ATOM   5832 N N   . SER E 3 55  ? -7.386  15.804  -53.713 1.00 72.83  ? 56  SER M N   1 
ATOM   5833 C CA  . SER E 3 55  ? -6.403  15.194  -54.599 1.00 74.71  ? 56  SER M CA  1 
ATOM   5834 C C   . SER E 3 55  ? -6.594  13.683  -54.645 1.00 73.80  ? 56  SER M C   1 
ATOM   5835 O O   . SER E 3 55  ? -6.686  13.025  -53.604 1.00 78.23  ? 56  SER M O   1 
ATOM   5836 C CB  . SER E 3 55  ? -4.989  15.534  -54.134 1.00 75.50  ? 56  SER M CB  1 
ATOM   5837 O OG  . SER E 3 55  ? -4.024  15.122  -55.087 1.00 73.33  ? 56  SER M OG  1 
ATOM   5838 N N   . GLY E 3 56  ? -6.655  13.133  -55.857 1.00 69.76  ? 57  GLY M N   1 
ATOM   5839 C CA  . GLY E 3 56  ? -6.827  11.710  -56.046 1.00 71.18  ? 57  GLY M CA  1 
ATOM   5840 C C   . GLY E 3 56  ? -8.265  11.245  -56.100 1.00 70.09  ? 57  GLY M C   1 
ATOM   5841 O O   . GLY E 3 56  ? -8.508  10.069  -56.402 1.00 72.35  ? 57  GLY M O   1 
ATOM   5842 N N   . VAL E 3 57  ? -9.221  12.125  -55.823 1.00 69.96  ? 58  VAL M N   1 
ATOM   5843 C CA  . VAL E 3 57  ? -10.638 11.771  -55.800 1.00 70.83  ? 58  VAL M CA  1 
ATOM   5844 C C   . VAL E 3 57  ? -11.143 11.633  -57.232 1.00 67.35  ? 58  VAL M C   1 
ATOM   5845 O O   . VAL E 3 57  ? -11.037 12.582  -58.022 1.00 70.50  ? 58  VAL M O   1 
ATOM   5846 C CB  . VAL E 3 57  ? -11.451 12.814  -55.017 1.00 70.26  ? 58  VAL M CB  1 
ATOM   5847 C CG1 . VAL E 3 57  ? -12.933 12.509  -55.104 1.00 68.56  ? 58  VAL M CG1 1 
ATOM   5848 C CG2 . VAL E 3 57  ? -10.995 12.856  -53.566 1.00 60.21  ? 58  VAL M CG2 1 
ATOM   5849 N N   . PRO E 3 58  ? -11.685 10.475  -57.609 1.00 70.12  ? 59  PRO M N   1 
ATOM   5850 C CA  . PRO E 3 58  ? -12.174 10.296  -58.981 1.00 68.97  ? 59  PRO M CA  1 
ATOM   5851 C C   . PRO E 3 58  ? -13.306 11.257  -59.317 1.00 72.37  ? 59  PRO M C   1 
ATOM   5852 O O   . PRO E 3 58  ? -13.998 11.784  -58.442 1.00 69.37  ? 59  PRO M O   1 
ATOM   5853 C CB  . PRO E 3 58  ? -12.655 8.839   -58.999 1.00 71.06  ? 59  PRO M CB  1 
ATOM   5854 C CG  . PRO E 3 58  ? -11.894 8.177   -57.895 1.00 66.64  ? 59  PRO M CG  1 
ATOM   5855 C CD  . PRO E 3 58  ? -11.739 9.225   -56.833 1.00 69.02  ? 59  PRO M CD  1 
ATOM   5856 N N   . ALA E 3 59  ? -13.490 11.476  -60.622 1.00 75.88  ? 60  ALA M N   1 
ATOM   5857 C CA  . ALA E 3 59  ? -14.467 12.450  -61.096 1.00 74.89  ? 60  ALA M CA  1 
ATOM   5858 C C   . ALA E 3 59  ? -15.906 12.015  -60.847 1.00 72.18  ? 60  ALA M C   1 
ATOM   5859 O O   . ALA E 3 59  ? -16.813 12.848  -60.943 1.00 64.27  ? 60  ALA M O   1 
ATOM   5860 C CB  . ALA E 3 59  ? -14.260 12.720  -62.586 1.00 74.52  ? 60  ALA M CB  1 
ATOM   5861 N N   . ARG E 3 60  ? -16.140 10.738  -60.533 1.00 73.52  ? 61  ARG M N   1 
ATOM   5862 C CA  . ARG E 3 60  ? -17.495 10.280  -60.252 1.00 71.18  ? 61  ARG M CA  1 
ATOM   5863 C C   . ARG E 3 60  ? -18.044 10.839  -58.947 1.00 67.36  ? 61  ARG M C   1 
ATOM   5864 O O   . ARG E 3 60  ? -19.257 10.763  -58.724 1.00 71.16  ? 61  ARG M O   1 
ATOM   5865 C CB  . ARG E 3 60  ? -17.544 8.752   -60.209 1.00 67.62  ? 61  ARG M CB  1 
ATOM   5866 C CG  . ARG E 3 60  ? -16.731 8.142   -59.081 1.00 66.88  ? 61  ARG M CG  1 
ATOM   5867 C CD  . ARG E 3 60  ? -16.598 6.639   -59.245 1.00 65.15  ? 61  ARG M CD  1 
ATOM   5868 N NE  . ARG E 3 60  ? -15.765 6.054   -58.202 1.00 69.09  ? 61  ARG M NE  1 
ATOM   5869 C CZ  . ARG E 3 60  ? -14.510 5.660   -58.375 1.00 70.16  ? 61  ARG M CZ  1 
ATOM   5870 N NH1 . ARG E 3 60  ? -13.905 5.772   -59.546 1.00 69.87  ? 61  ARG M NH1 1 
ATOM   5871 N NH2 . ARG E 3 60  ? -13.846 5.142   -57.346 1.00 65.00  ? 61  ARG M NH2 1 
ATOM   5872 N N   . PHE E 3 61  ? -17.192 11.398  -58.090 1.00 66.86  ? 62  PHE M N   1 
ATOM   5873 C CA  . PHE E 3 61  ? -17.633 12.013  -56.847 1.00 66.70  ? 62  PHE M CA  1 
ATOM   5874 C C   . PHE E 3 61  ? -18.017 13.467  -57.086 1.00 67.64  ? 62  PHE M C   1 
ATOM   5875 O O   . PHE E 3 61  ? -17.383 14.169  -57.879 1.00 69.37  ? 62  PHE M O   1 
ATOM   5876 C CB  . PHE E 3 61  ? -16.534 11.944  -55.785 1.00 66.85  ? 62  PHE M CB  1 
ATOM   5877 C CG  . PHE E 3 61  ? -16.245 10.554  -55.294 1.00 65.52  ? 62  PHE M CG  1 
ATOM   5878 C CD1 . PHE E 3 61  ? -15.109 9.880   -55.708 1.00 63.51  ? 62  PHE M CD1 1 
ATOM   5879 C CD2 . PHE E 3 61  ? -17.106 9.922   -54.415 1.00 64.53  ? 62  PHE M CD2 1 
ATOM   5880 C CE1 . PHE E 3 61  ? -14.835 8.604   -55.251 1.00 67.16  ? 62  PHE M CE1 1 
ATOM   5881 C CE2 . PHE E 3 61  ? -16.834 8.647   -53.952 1.00 62.42  ? 62  PHE M CE2 1 
ATOM   5882 C CZ  . PHE E 3 61  ? -15.704 7.982   -54.382 1.00 62.06  ? 62  PHE M CZ  1 
ATOM   5883 N N   . SER E 3 62  ? -19.058 13.915  -56.387 1.00 69.78  ? 63  SER M N   1 
ATOM   5884 C CA  . SER E 3 62  ? -19.453 15.315  -56.436 1.00 69.88  ? 63  SER M CA  1 
ATOM   5885 C C   . SER E 3 62  ? -20.132 15.683  -55.126 1.00 72.56  ? 63  SER M C   1 
ATOM   5886 O O   . SER E 3 62  ? -20.598 14.819  -54.380 1.00 71.30  ? 63  SER M O   1 
ATOM   5887 C CB  . SER E 3 62  ? -20.378 15.602  -57.625 1.00 66.01  ? 63  SER M CB  1 
ATOM   5888 O OG  . SER E 3 62  ? -21.590 14.876  -57.514 1.00 68.28  ? 63  SER M OG  1 
ATOM   5889 N N   . GLY E 3 63  ? -20.169 16.978  -54.846 1.00 74.05  ? 64  GLY M N   1 
ATOM   5890 C CA  . GLY E 3 63  ? -20.826 17.478  -53.656 1.00 75.88  ? 64  GLY M CA  1 
ATOM   5891 C C   . GLY E 3 63  ? -21.765 18.612  -53.989 1.00 82.52  ? 64  GLY M C   1 
ATOM   5892 O O   . GLY E 3 63  ? -21.523 19.403  -54.901 1.00 83.51  ? 64  GLY M O   1 
ATOM   5893 N N   . SER E 3 64  ? -22.861 18.685  -53.236 1.00 79.74  ? 65  SER M N   1 
ATOM   5894 C CA  . SER E 3 64  ? -23.857 19.722  -53.457 1.00 81.47  ? 65  SER M CA  1 
ATOM   5895 C C   . SER E 3 64  ? -24.562 20.018  -52.140 1.00 84.52  ? 65  SER M C   1 
ATOM   5896 O O   . SER E 3 64  ? -24.296 19.387  -51.114 1.00 87.86  ? 65  SER M O   1 
ATOM   5897 C CB  . SER E 3 64  ? -24.857 19.309  -54.543 1.00 82.95  ? 65  SER M CB  1 
ATOM   5898 O OG  . SER E 3 64  ? -24.203 19.060  -55.775 1.00 89.48  ? 65  SER M OG  1 
ATOM   5899 N N   . GLY E 3 65  ? -25.472 20.978  -52.178 1.00 81.87  ? 66  GLY M N   1 
ATOM   5900 C CA  . GLY E 3 65  ? -26.276 21.338  -51.029 1.00 81.08  ? 66  GLY M CA  1 
ATOM   5901 C C   . GLY E 3 65  ? -25.912 22.709  -50.486 1.00 86.70  ? 66  GLY M C   1 
ATOM   5902 O O   . GLY E 3 65  ? -24.935 23.342  -50.888 1.00 87.36  ? 66  GLY M O   1 
ATOM   5903 N N   . SER E 3 66  ? -26.729 23.153  -49.537 1.00 87.16  ? 67  SER M N   1 
ATOM   5904 C CA  . SER E 3 66  ? -26.528 24.440  -48.882 1.00 86.65  ? 67  SER M CA  1 
ATOM   5905 C C   . SER E 3 66  ? -27.393 24.486  -47.631 1.00 87.61  ? 67  SER M C   1 
ATOM   5906 O O   . SER E 3 66  ? -28.181 23.574  -47.357 1.00 87.71  ? 67  SER M O   1 
ATOM   5907 C CB  . SER E 3 66  ? -26.857 25.610  -49.815 1.00 86.02  ? 67  SER M CB  1 
ATOM   5908 O OG  . SER E 3 66  ? -28.231 25.618  -50.163 1.00 79.86  ? 67  SER M OG  1 
ATOM   5909 N N   . GLY E 3 67  ? -27.214 25.558  -46.861 1.00 86.79  ? 68  GLY M N   1 
ATOM   5910 C CA  . GLY E 3 67  ? -28.042 25.826  -45.702 1.00 84.77  ? 68  GLY M CA  1 
ATOM   5911 C C   . GLY E 3 67  ? -28.051 24.725  -44.664 1.00 86.40  ? 68  GLY M C   1 
ATOM   5912 O O   . GLY E 3 67  ? -27.128 24.613  -43.851 1.00 83.83  ? 68  GLY M O   1 
ATOM   5913 N N   . THR E 3 68  ? -29.099 23.902  -44.685 1.00 88.54  ? 69  THR M N   1 
ATOM   5914 C CA  . THR E 3 68  ? -29.272 22.836  -43.708 1.00 88.48  ? 69  THR M CA  1 
ATOM   5915 C C   . THR E 3 68  ? -29.245 21.445  -44.329 1.00 85.39  ? 69  THR M C   1 
ATOM   5916 O O   . THR E 3 68  ? -29.493 20.462  -43.621 1.00 90.85  ? 69  THR M O   1 
ATOM   5917 C CB  . THR E 3 68  ? -30.586 23.030  -42.944 1.00 91.81  ? 69  THR M CB  1 
ATOM   5918 O OG1 . THR E 3 68  ? -30.719 22.006  -41.950 1.00 92.66  ? 69  THR M OG1 1 
ATOM   5919 C CG2 . THR E 3 68  ? -31.769 22.957  -43.900 1.00 87.88  ? 69  THR M CG2 1 
ATOM   5920 N N   . SER E 3 69  ? -28.956 21.327  -45.624 1.00 85.04  ? 70  SER M N   1 
ATOM   5921 C CA  . SER E 3 69  ? -28.960 20.029  -46.291 1.00 84.89  ? 70  SER M CA  1 
ATOM   5922 C C   . SER E 3 69  ? -27.819 19.983  -47.293 1.00 89.60  ? 70  SER M C   1 
ATOM   5923 O O   . SER E 3 69  ? -27.771 20.808  -48.210 1.00 91.90  ? 70  SER M O   1 
ATOM   5924 C CB  . SER E 3 69  ? -30.299 19.770  -46.990 1.00 80.83  ? 70  SER M CB  1 
ATOM   5925 O OG  . SER E 3 69  ? -30.274 18.544  -47.701 1.00 83.16  ? 70  SER M OG  1 
ATOM   5926 N N   . TYR E 3 70  ? -26.903 19.031  -47.122 1.00 90.27  ? 71  TYR M N   1 
ATOM   5927 C CA  . TYR E 3 70  ? -25.823 18.826  -48.077 1.00 84.44  ? 71  TYR M CA  1 
ATOM   5928 C C   . TYR E 3 70  ? -25.831 17.373  -48.532 1.00 82.60  ? 71  TYR M C   1 
ATOM   5929 O O   . TYR E 3 70  ? -26.499 16.522  -47.942 1.00 83.16  ? 71  TYR M O   1 
ATOM   5930 C CB  . TYR E 3 70  ? -24.464 19.204  -47.477 1.00 82.56  ? 71  TYR M CB  1 
ATOM   5931 C CG  . TYR E 3 70  ? -24.313 20.683  -47.202 1.00 86.77  ? 71  TYR M CG  1 
ATOM   5932 C CD1 . TYR E 3 70  ? -24.886 21.261  -46.076 1.00 83.47  ? 71  TYR M CD1 1 
ATOM   5933 C CD2 . TYR E 3 70  ? -23.612 21.505  -48.074 1.00 89.47  ? 71  TYR M CD2 1 
ATOM   5934 C CE1 . TYR E 3 70  ? -24.755 22.612  -45.820 1.00 87.06  ? 71  TYR M CE1 1 
ATOM   5935 C CE2 . TYR E 3 70  ? -23.474 22.858  -47.826 1.00 87.94  ? 71  TYR M CE2 1 
ATOM   5936 C CZ  . TYR E 3 70  ? -24.049 23.406  -46.697 1.00 88.38  ? 71  TYR M CZ  1 
ATOM   5937 O OH  . TYR E 3 70  ? -23.918 24.752  -46.447 1.00 91.84  ? 71  TYR M OH  1 
ATOM   5938 N N   . SER E 3 71  ? -25.071 17.081  -49.586 1.00 79.41  ? 72  SER M N   1 
ATOM   5939 C CA  . SER E 3 71  ? -25.128 15.752  -50.175 1.00 78.03  ? 72  SER M CA  1 
ATOM   5940 C C   . SER E 3 71  ? -23.830 15.431  -50.903 1.00 77.39  ? 72  SER M C   1 
ATOM   5941 O O   . SER E 3 71  ? -23.241 16.296  -51.562 1.00 80.95  ? 72  SER M O   1 
ATOM   5942 C CB  . SER E 3 71  ? -26.313 15.625  -51.140 1.00 79.88  ? 72  SER M CB  1 
ATOM   5943 O OG  . SER E 3 71  ? -26.122 16.433  -52.289 1.00 77.64  ? 72  SER M OG  1 
ATOM   5944 N N   . LEU E 3 72  ? -23.409 14.174  -50.772 1.00 75.48  ? 73  LEU M N   1 
ATOM   5945 C CA  . LEU E 3 72  ? -22.309 13.586  -51.528 1.00 68.10  ? 73  LEU M CA  1 
ATOM   5946 C C   . LEU E 3 72  ? -22.903 12.618  -52.543 1.00 66.65  ? 73  LEU M C   1 
ATOM   5947 O O   . LEU E 3 72  ? -23.740 11.784  -52.186 1.00 70.62  ? 73  LEU M O   1 
ATOM   5948 C CB  . LEU E 3 72  ? -21.338 12.855  -50.594 1.00 65.90  ? 73  LEU M CB  1 
ATOM   5949 C CG  . LEU E 3 72  ? -20.026 12.281  -51.137 1.00 66.65  ? 73  LEU M CG  1 
ATOM   5950 C CD1 . LEU E 3 72  ? -18.936 12.356  -50.078 1.00 65.80  ? 73  LEU M CD1 1 
ATOM   5951 C CD2 . LEU E 3 72  ? -20.200 10.846  -51.611 1.00 62.68  ? 73  LEU M CD2 1 
ATOM   5952 N N   . THR E 3 73  ? -22.469 12.715  -53.798 1.00 67.55  ? 74  THR M N   1 
ATOM   5953 C CA  . THR E 3 73  ? -23.087 11.969  -54.887 1.00 66.11  ? 74  THR M CA  1 
ATOM   5954 C C   . THR E 3 73  ? -22.033 11.208  -55.679 1.00 67.30  ? 74  THR M C   1 
ATOM   5955 O O   . THR E 3 73  ? -20.994 11.771  -56.043 1.00 70.05  ? 74  THR M O   1 
ATOM   5956 C CB  . THR E 3 73  ? -23.865 12.910  -55.817 1.00 71.20  ? 74  THR M CB  1 
ATOM   5957 O OG1 . THR E 3 73  ? -25.046 13.384  -55.154 1.00 69.09  ? 74  THR M OG1 1 
ATOM   5958 C CG2 . THR E 3 73  ? -24.264 12.197  -57.101 1.00 67.57  ? 74  THR M CG2 1 
ATOM   5959 N N   . ILE E 3 74  ? -22.305 9.930   -55.934 1.00 67.59  ? 75  ILE M N   1 
ATOM   5960 C CA  . ILE E 3 74  ? -21.529 9.101   -56.851 1.00 67.15  ? 75  ILE M CA  1 
ATOM   5961 C C   . ILE E 3 74  ? -22.392 8.852   -58.079 1.00 70.54  ? 75  ILE M C   1 
ATOM   5962 O O   . ILE E 3 74  ? -23.519 8.348   -57.961 1.00 71.14  ? 75  ILE M O   1 
ATOM   5963 C CB  . ILE E 3 74  ? -21.110 7.766   -56.219 1.00 66.92  ? 75  ILE M CB  1 
ATOM   5964 C CG1 . ILE E 3 74  ? -19.971 7.948   -55.219 1.00 64.30  ? 75  ILE M CG1 1 
ATOM   5965 C CG2 . ILE E 3 74  ? -20.672 6.804   -57.313 1.00 68.86  ? 75  ILE M CG2 1 
ATOM   5966 C CD1 . ILE E 3 74  ? -19.560 6.642   -54.566 1.00 63.69  ? 75  ILE M CD1 1 
ATOM   5967 N N   . SER E 3 75  ? -21.866 9.215   -59.251 1.00 73.07  ? 76  SER M N   1 
ATOM   5968 C CA  . SER E 3 75  ? -22.581 8.995   -60.504 1.00 68.92  ? 76  SER M CA  1 
ATOM   5969 C C   . SER E 3 75  ? -22.758 7.507   -60.781 1.00 68.39  ? 76  SER M C   1 
ATOM   5970 O O   . SER E 3 75  ? -23.879 7.033   -61.001 1.00 66.05  ? 76  SER M O   1 
ATOM   5971 C CB  . SER E 3 75  ? -21.834 9.675   -61.653 1.00 62.52  ? 76  SER M CB  1 
ATOM   5972 O OG  . SER E 3 75  ? -20.559 9.085   -61.849 1.00 65.37  ? 76  SER M OG  1 
ATOM   5973 N N   . SER E 3 76  ? -21.662 6.751   -60.765 1.00 69.90  ? 77  SER M N   1 
ATOM   5974 C CA  . SER E 3 76  ? -21.690 5.309   -60.997 1.00 69.71  ? 77  SER M CA  1 
ATOM   5975 C C   . SER E 3 76  ? -20.884 4.628   -59.899 1.00 72.09  ? 77  SER M C   1 
ATOM   5976 O O   . SER E 3 76  ? -19.661 4.792   -59.830 1.00 72.95  ? 77  SER M O   1 
ATOM   5977 C CB  . SER E 3 76  ? -21.137 4.961   -62.379 1.00 69.78  ? 77  SER M CB  1 
ATOM   5978 O OG  . SER E 3 76  ? -21.166 3.563   -62.603 1.00 71.90  ? 77  SER M OG  1 
ATOM   5979 N N   . MET E 3 77  ? -21.572 3.879   -59.039 1.00 69.51  ? 78  MET M N   1 
ATOM   5980 C CA  . MET E 3 77  ? -20.910 3.170   -57.952 1.00 65.36  ? 78  MET M CA  1 
ATOM   5981 C C   . MET E 3 77  ? -19.824 2.236   -58.471 1.00 66.23  ? 78  MET M C   1 
ATOM   5982 O O   . MET E 3 77  ? -20.017 1.507   -59.446 1.00 69.56  ? 78  MET M O   1 
ATOM   5983 C CB  . MET E 3 77  ? -21.934 2.380   -57.135 1.00 67.96  ? 78  MET M CB  1 
ATOM   5984 C CG  . MET E 3 77  ? -21.313 1.386   -56.160 1.00 62.35  ? 78  MET M CG  1 
ATOM   5985 S SD  . MET E 3 77  ? -20.829 2.128   -54.597 1.00 67.43  ? 78  MET M SD  1 
ATOM   5986 C CE  . MET E 3 77  ? -22.104 3.365   -54.423 1.00 66.26  ? 78  MET M CE  1 
ATOM   5987 N N   . GLU E 3 78  ? -18.674 2.267   -57.805 1.00 65.63  ? 79  GLU M N   1 
ATOM   5988 C CA  . GLU E 3 78  ? -17.589 1.333   -58.046 1.00 66.35  ? 79  GLU M CA  1 
ATOM   5989 C C   . GLU E 3 78  ? -17.325 0.528   -56.780 1.00 58.91  ? 79  GLU M C   1 
ATOM   5990 O O   . GLU E 3 78  ? -17.672 0.944   -55.671 1.00 57.16  ? 79  GLU M O   1 
ATOM   5991 C CB  . GLU E 3 78  ? -16.308 2.060   -58.483 1.00 62.45  ? 79  GLU M CB  1 
ATOM   5992 C CG  . GLU E 3 78  ? -16.451 2.861   -59.770 1.00 70.37  ? 79  GLU M CG  1 
ATOM   5993 C CD  . GLU E 3 78  ? -16.633 1.984   -60.995 1.00 77.61  ? 79  GLU M CD  1 
ATOM   5994 O OE1 . GLU E 3 78  ? -16.302 0.782   -60.929 1.00 77.45  ? 79  GLU M OE1 1 
ATOM   5995 O OE2 . GLU E 3 78  ? -17.108 2.500   -62.029 1.00 79.13  ? 79  GLU M OE2 1 
ATOM   5996 N N   . ALA E 3 79  ? -16.716 -0.647  -56.963 1.00 61.68  ? 80  ALA M N   1 
ATOM   5997 C CA  . ALA E 3 79  ? -16.458 -1.531  -55.831 1.00 55.05  ? 80  ALA M CA  1 
ATOM   5998 C C   . ALA E 3 79  ? -15.542 -0.871  -54.807 1.00 58.01  ? 80  ALA M C   1 
ATOM   5999 O O   . ALA E 3 79  ? -15.716 -1.056  -53.597 1.00 59.16  ? 80  ALA M O   1 
ATOM   6000 C CB  . ALA E 3 79  ? -15.856 -2.848  -56.321 1.00 62.32  ? 80  ALA M CB  1 
ATOM   6001 N N   . GLU E 3 80  ? -14.562 -0.094  -55.273 1.00 57.55  ? 81  GLU M N   1 
ATOM   6002 C CA  . GLU E 3 80  ? -13.616 0.556   -54.374 1.00 56.24  ? 81  GLU M CA  1 
ATOM   6003 C C   . GLU E 3 80  ? -14.225 1.720   -53.602 1.00 52.99  ? 81  GLU M C   1 
ATOM   6004 O O   . GLU E 3 80  ? -13.561 2.259   -52.711 1.00 44.02  ? 81  GLU M O   1 
ATOM   6005 C CB  . GLU E 3 80  ? -12.397 1.038   -55.162 1.00 58.28  ? 81  GLU M CB  1 
ATOM   6006 C CG  . GLU E 3 80  ? -12.738 1.851   -56.399 1.00 63.74  ? 81  GLU M CG  1 
ATOM   6007 C CD  . GLU E 3 80  ? -11.527 2.544   -56.989 1.00 70.78  ? 81  GLU M CD  1 
ATOM   6008 O OE1 . GLU E 3 80  ? -10.444 1.924   -57.023 1.00 76.96  ? 81  GLU M OE1 1 
ATOM   6009 O OE2 . GLU E 3 80  ? -11.659 3.709   -57.420 1.00 73.84  ? 81  GLU M OE2 1 
ATOM   6010 N N   . ASP E 3 81  ? -15.457 2.122   -53.915 1.00 52.10  ? 82  ASP M N   1 
ATOM   6011 C CA  . ASP E 3 81  ? -16.101 3.218   -53.201 1.00 52.61  ? 82  ASP M CA  1 
ATOM   6012 C C   . ASP E 3 81  ? -16.758 2.780   -51.899 1.00 53.99  ? 82  ASP M C   1 
ATOM   6013 O O   . ASP E 3 81  ? -17.210 3.642   -51.136 1.00 53.80  ? 82  ASP M O   1 
ATOM   6014 C CB  . ASP E 3 81  ? -17.145 3.892   -54.095 1.00 55.98  ? 82  ASP M CB  1 
ATOM   6015 C CG  . ASP E 3 81  ? -16.551 4.438   -55.376 1.00 59.92  ? 82  ASP M CG  1 
ATOM   6016 O OD1 . ASP E 3 81  ? -15.338 4.736   -55.388 1.00 62.84  ? 82  ASP M OD1 1 
ATOM   6017 O OD2 . ASP E 3 81  ? -17.296 4.574   -56.370 1.00 63.93  ? 82  ASP M OD2 1 
ATOM   6018 N N   . ALA E 3 82  ? -16.831 1.479   -51.631 1.00 51.97  ? 83  ALA M N   1 
ATOM   6019 C CA  . ALA E 3 82  ? -17.435 0.990   -50.397 1.00 49.92  ? 83  ALA M CA  1 
ATOM   6020 C C   . ALA E 3 82  ? -16.586 1.405   -49.200 1.00 49.80  ? 83  ALA M C   1 
ATOM   6021 O O   . ALA E 3 82  ? -15.436 0.971   -49.067 1.00 59.43  ? 83  ALA M O   1 
ATOM   6022 C CB  . ALA E 3 82  ? -17.584 -0.528  -50.452 1.00 45.78  ? 83  ALA M CB  1 
ATOM   6023 N N   . ALA E 3 83  ? -17.164 2.226   -48.319 1.00 47.71  ? 84  ALA M N   1 
ATOM   6024 C CA  . ALA E 3 83  ? -16.436 2.790   -47.184 1.00 45.13  ? 84  ALA M CA  1 
ATOM   6025 C C   . ALA E 3 83  ? -17.372 3.595   -46.293 1.00 45.70  ? 84  ALA M C   1 
ATOM   6026 O O   . ALA E 3 83  ? -18.556 3.738   -46.605 1.00 49.59  ? 84  ALA M O   1 
ATOM   6027 C CB  . ALA E 3 83  ? -15.284 3.680   -47.662 1.00 50.29  ? 84  ALA M CB  1 
ATOM   6028 N N   . ALA E 3 84  ? -16.866 4.135   -45.189 1.00 41.90  ? 85  ALA M N   1 
ATOM   6029 C CA  . ALA E 3 84  ? -17.638 5.065   -44.384 1.00 46.68  ? 85  ALA M CA  1 
ATOM   6030 C C   . ALA E 3 84  ? -17.376 6.486   -44.861 1.00 49.50  ? 85  ALA M C   1 
ATOM   6031 O O   . ALA E 3 84  ? -16.252 6.832   -45.236 1.00 50.20  ? 85  ALA M O   1 
ATOM   6032 C CB  . ALA E 3 84  ? -17.282 4.931   -42.902 1.00 42.33  ? 85  ALA M CB  1 
ATOM   6033 N N   . TYR E 3 85  ? -18.423 7.305   -44.854 1.00 48.37  ? 86  TYR M N   1 
ATOM   6034 C CA  . TYR E 3 85  ? -18.324 8.697   -45.274 1.00 50.00  ? 86  TYR M CA  1 
ATOM   6035 C C   . TYR E 3 85  ? -18.869 9.577   -44.163 1.00 51.62  ? 86  TYR M C   1 
ATOM   6036 O O   . TYR E 3 85  ? -20.027 9.427   -43.760 1.00 48.44  ? 86  TYR M O   1 
ATOM   6037 C CB  . TYR E 3 85  ? -19.080 8.938   -46.583 1.00 52.90  ? 86  TYR M CB  1 
ATOM   6038 C CG  . TYR E 3 85  ? -18.458 8.249   -47.775 1.00 52.04  ? 86  TYR M CG  1 
ATOM   6039 C CD1 . TYR E 3 85  ? -17.449 8.862   -48.506 1.00 50.70  ? 86  TYR M CD1 1 
ATOM   6040 C CD2 . TYR E 3 85  ? -18.877 6.984   -48.168 1.00 50.02  ? 86  TYR M CD2 1 
ATOM   6041 C CE1 . TYR E 3 85  ? -16.875 8.236   -49.596 1.00 49.37  ? 86  TYR M CE1 1 
ATOM   6042 C CE2 . TYR E 3 85  ? -18.309 6.351   -49.257 1.00 47.87  ? 86  TYR M CE2 1 
ATOM   6043 C CZ  . TYR E 3 85  ? -17.309 6.981   -49.967 1.00 47.57  ? 86  TYR M CZ  1 
ATOM   6044 O OH  . TYR E 3 85  ? -16.739 6.355   -51.052 1.00 54.88  ? 86  TYR M OH  1 
ATOM   6045 N N   . TYR E 3 86  ? -18.040 10.493  -43.677 1.00 49.86  ? 87  TYR M N   1 
ATOM   6046 C CA  . TYR E 3 86  ? -18.394 11.367  -42.567 1.00 59.39  ? 87  TYR M CA  1 
ATOM   6047 C C   . TYR E 3 86  ? -18.481 12.802  -43.062 1.00 65.17  ? 87  TYR M C   1 
ATOM   6048 O O   . TYR E 3 86  ? -17.570 13.280  -43.743 1.00 59.00  ? 87  TYR M O   1 
ATOM   6049 C CB  . TYR E 3 86  ? -17.359 11.272  -41.442 1.00 56.44  ? 87  TYR M CB  1 
ATOM   6050 C CG  . TYR E 3 86  ? -17.244 9.908   -40.798 1.00 58.45  ? 87  TYR M CG  1 
ATOM   6051 C CD1 . TYR E 3 86  ? -16.482 8.905   -41.381 1.00 50.48  ? 87  TYR M CD1 1 
ATOM   6052 C CD2 . TYR E 3 86  ? -17.883 9.630   -39.598 1.00 55.63  ? 87  TYR M CD2 1 
ATOM   6053 C CE1 . TYR E 3 86  ? -16.369 7.660   -40.794 1.00 54.70  ? 87  TYR M CE1 1 
ATOM   6054 C CE2 . TYR E 3 86  ? -17.776 8.387   -39.003 1.00 48.63  ? 87  TYR M CE2 1 
ATOM   6055 C CZ  . TYR E 3 86  ? -17.018 7.406   -39.606 1.00 57.43  ? 87  TYR M CZ  1 
ATOM   6056 O OH  . TYR E 3 86  ? -16.909 6.168   -39.016 1.00 55.81  ? 87  TYR M OH  1 
ATOM   6057 N N   . CYS E 3 87  ? -19.564 13.492  -42.719 1.00 62.59  ? 88  CYS M N   1 
ATOM   6058 C CA  . CYS E 3 87  ? -19.598 14.929  -42.934 1.00 67.68  ? 88  CYS M CA  1 
ATOM   6059 C C   . CYS E 3 87  ? -19.125 15.648  -41.677 1.00 70.67  ? 88  CYS M C   1 
ATOM   6060 O O   . CYS E 3 87  ? -19.372 15.210  -40.550 1.00 72.40  ? 88  CYS M O   1 
ATOM   6061 C CB  . CYS E 3 87  ? -20.994 15.416  -43.347 1.00 72.48  ? 88  CYS M CB  1 
ATOM   6062 S SG  . CYS E 3 87  ? -22.407 14.967  -42.300 1.00 76.38  ? 88  CYS M SG  1 
ATOM   6063 N N   . GLN E 3 88  ? -18.438 16.766  -41.890 1.00 72.95  ? 89  GLN M N   1 
ATOM   6064 C CA  . GLN E 3 88  ? -17.783 17.508  -40.825 1.00 75.98  ? 89  GLN M CA  1 
ATOM   6065 C C   . GLN E 3 88  ? -17.872 18.995  -41.115 1.00 80.11  ? 89  GLN M C   1 
ATOM   6066 O O   . GLN E 3 88  ? -17.611 19.444  -42.241 1.00 78.81  ? 89  GLN M O   1 
ATOM   6067 C CB  . GLN E 3 88  ? -16.319 17.093  -40.665 1.00 73.24  ? 89  GLN M CB  1 
ATOM   6068 C CG  . GLN E 3 88  ? -15.514 17.954  -39.703 1.00 75.71  ? 89  GLN M CG  1 
ATOM   6069 C CD  . GLN E 3 88  ? -14.821 19.113  -40.397 1.00 81.10  ? 89  GLN M CD  1 
ATOM   6070 O OE1 . GLN E 3 88  ? -14.212 18.945  -41.453 1.00 77.57  ? 89  GLN M OE1 1 
ATOM   6071 N NE2 . GLN E 3 88  ? -14.919 20.299  -39.808 1.00 81.92  ? 89  GLN M NE2 1 
ATOM   6072 N N   . GLN E 3 89  ? -18.199 19.746  -40.066 1.00 82.96  ? 90  GLN M N   1 
ATOM   6073 C CA  . GLN E 3 89  ? -18.455 21.173  -40.127 1.00 82.91  ? 90  GLN M CA  1 
ATOM   6074 C C   . GLN E 3 89  ? -17.628 21.893  -39.071 1.00 85.03  ? 90  GLN M C   1 
ATOM   6075 O O   . GLN E 3 89  ? -17.263 21.318  -38.040 1.00 86.29  ? 90  GLN M O   1 
ATOM   6076 C CB  . GLN E 3 89  ? -19.960 21.453  -39.913 1.00 83.68  ? 90  GLN M CB  1 
ATOM   6077 C CG  . GLN E 3 89  ? -20.360 22.918  -39.800 1.00 88.74  ? 90  GLN M CG  1 
ATOM   6078 C CD  . GLN E 3 89  ? -21.189 23.199  -38.559 1.00 87.19  ? 90  GLN M CD  1 
ATOM   6079 O OE1 . GLN E 3 89  ? -21.527 22.287  -37.803 1.00 87.96  ? 90  GLN M OE1 1 
ATOM   6080 N NE2 . GLN E 3 89  ? -21.520 24.467  -38.344 1.00 89.00  ? 90  GLN M NE2 1 
ATOM   6081 N N   . TRP E 3 90  ? -17.334 23.159  -39.350 1.00 89.36  ? 91  TRP M N   1 
ATOM   6082 C CA  . TRP E 3 90  ? -16.637 24.044  -38.430 1.00 91.78  ? 91  TRP M CA  1 
ATOM   6083 C C   . TRP E 3 90  ? -17.517 25.254  -38.155 1.00 94.41  ? 91  TRP M C   1 
ATOM   6084 O O   . TRP E 3 90  ? -17.960 25.930  -39.090 1.00 90.43  ? 91  TRP M O   1 
ATOM   6085 C CB  . TRP E 3 90  ? -15.285 24.480  -39.000 1.00 88.05  ? 91  TRP M CB  1 
ATOM   6086 C CG  . TRP E 3 90  ? -14.712 25.667  -38.302 1.00 89.03  ? 91  TRP M CG  1 
ATOM   6087 C CD1 . TRP E 3 90  ? -14.632 26.941  -38.783 1.00 92.98  ? 91  TRP M CD1 1 
ATOM   6088 C CD2 . TRP E 3 90  ? -14.169 25.701  -36.979 1.00 90.80  ? 91  TRP M CD2 1 
ATOM   6089 N NE1 . TRP E 3 90  ? -14.054 27.763  -37.847 1.00 96.92  ? 91  TRP M NE1 1 
ATOM   6090 C CE2 . TRP E 3 90  ? -13.762 27.026  -36.729 1.00 92.53  ? 91  TRP M CE2 1 
ATOM   6091 C CE3 . TRP E 3 90  ? -13.980 24.737  -35.983 1.00 91.39  ? 91  TRP M CE3 1 
ATOM   6092 C CZ2 . TRP E 3 90  ? -13.178 27.412  -35.526 1.00 92.99  ? 91  TRP M CZ2 1 
ATOM   6093 C CZ3 . TRP E 3 90  ? -13.401 25.123  -34.789 1.00 91.75  ? 91  TRP M CZ3 1 
ATOM   6094 C CH2 . TRP E 3 90  ? -13.006 26.448  -34.571 1.00 94.00  ? 91  TRP M CH2 1 
ATOM   6095 N N   . SER E 3 91  ? -17.770 25.519  -36.878 1.00 92.68  ? 92  SER M N   1 
ATOM   6096 C CA  . SER E 3 91  ? -18.546 26.668  -36.440 0.82 90.68  ? 92  SER M CA  1 
ATOM   6097 C C   . SER E 3 91  ? -17.635 27.650  -35.718 1.00 91.56  ? 92  SER M C   1 
ATOM   6098 O O   . SER E 3 91  ? -16.768 27.248  -34.934 1.00 92.17  ? 92  SER M O   1 
ATOM   6099 C CB  . SER E 3 91  ? -19.691 26.237  -35.518 1.00 90.66  ? 92  SER M CB  1 
ATOM   6100 O OG  . SER E 3 91  ? -20.527 25.286  -36.155 1.00 90.20  ? 92  SER M OG  1 
ATOM   6101 N N   . SER E 3 92  ? -17.840 28.935  -35.984 1.00 93.33  ? 93  SER M N   1 
ATOM   6102 C CA  . SER E 3 92  ? -17.004 29.982  -35.412 1.00 94.15  ? 93  SER M CA  1 
ATOM   6103 C C   . SER E 3 92  ? -17.704 30.677  -34.251 1.00 91.36  ? 93  SER M C   1 
ATOM   6104 O O   . SER E 3 92  ? -17.082 30.975  -33.231 1.00 87.97  ? 93  SER M O   1 
ATOM   6105 C CB  . SER E 3 92  ? -16.628 31.005  -36.486 1.00 93.12  ? 93  SER M CB  1 
ATOM   6106 O OG  . SER E 3 92  ? -17.781 31.479  -37.160 1.00 91.37  ? 93  SER M OG  1 
ATOM   6107 N N   . PRO E 3 94  ? -19.413 30.087  -31.640 1.00 90.10  ? 95  PRO M N   1 
ATOM   6108 C CA  . PRO E 3 94  ? -18.700 29.142  -30.770 1.00 89.71  ? 95  PRO M CA  1 
ATOM   6109 C C   . PRO E 3 94  ? -17.784 28.170  -31.547 1.00 91.41  ? 95  PRO M C   1 
ATOM   6110 O O   . PRO E 3 94  ? -18.251 27.316  -32.298 1.00 88.36  ? 95  PRO M O   1 
ATOM   6111 C CB  . PRO E 3 94  ? -19.835 28.387  -30.061 1.00 87.01  ? 95  PRO M CB  1 
ATOM   6112 C CG  . PRO E 3 94  ? -21.053 28.560  -30.969 1.00 86.70  ? 95  PRO M CG  1 
ATOM   6113 C CD  . PRO E 3 94  ? -20.771 29.657  -31.953 1.00 86.14  ? 95  PRO M CD  1 
ATOM   6114 N N   . PRO E 3 95  A -16.449 28.367  -31.400 1.00 89.23  ? 95  PRO M N   1 
ATOM   6115 C CA  . PRO E 3 95  A -15.479 27.545  -32.142 1.00 89.61  ? 95  PRO M CA  1 
ATOM   6116 C C   . PRO E 3 95  A -15.669 26.065  -31.853 1.00 89.53  ? 95  PRO M C   1 
ATOM   6117 O O   . PRO E 3 95  A -15.385 25.600  -30.746 1.00 87.64  ? 95  PRO M O   1 
ATOM   6118 C CB  . PRO E 3 95  A -14.130 28.057  -31.634 1.00 84.49  ? 95  PRO M CB  1 
ATOM   6119 C CG  . PRO E 3 95  A -14.430 28.721  -30.323 1.00 88.39  ? 95  PRO M CG  1 
ATOM   6120 C CD  . PRO E 3 95  A -15.799 29.312  -30.470 1.00 88.96  ? 95  PRO M CD  1 
ATOM   6121 N N   . MET E 3 96  B -16.148 25.312  -32.842 1.00 90.02  ? 95  MET M N   1 
ATOM   6122 C CA  . MET E 3 96  B -16.453 23.900  -32.640 1.00 89.11  ? 95  MET M CA  1 
ATOM   6123 C C   . MET E 3 96  B -16.297 23.154  -33.955 1.00 88.99  ? 95  MET M C   1 
ATOM   6124 O O   . MET E 3 96  B -16.831 23.583  -34.981 1.00 87.85  ? 95  MET M O   1 
ATOM   6125 C CB  . MET E 3 96  B -17.874 23.722  -32.092 1.00 90.95  ? 95  MET M CB  1 
ATOM   6126 C CG  . MET E 3 96  B -18.312 22.274  -31.923 1.00 88.12  ? 95  MET M CG  1 
ATOM   6127 S SD  . MET E 3 96  B -17.571 21.456  -30.498 1.00 93.64  ? 95  MET M SD  1 
ATOM   6128 C CE  . MET E 3 96  B -18.464 19.903  -30.506 1.00 84.73  ? 95  MET M CE  1 
ATOM   6129 N N   . LEU E 3 97  ? -15.580 22.035  -33.919 1.00 85.48  ? 96  LEU M N   1 
ATOM   6130 C CA  . LEU E 3 97  ? -15.400 21.169  -35.080 1.00 82.97  ? 96  LEU M CA  1 
ATOM   6131 C C   . LEU E 3 97  ? -16.193 19.895  -34.820 1.00 80.92  ? 96  LEU M C   1 
ATOM   6132 O O   . LEU E 3 97  ? -15.860 19.125  -33.913 1.00 82.96  ? 96  LEU M O   1 
ATOM   6133 C CB  . LEU E 3 97  ? -13.918 20.878  -35.319 1.00 80.86  ? 96  LEU M CB  1 
ATOM   6134 C CG  . LEU E 3 97  ? -13.456 20.316  -36.669 1.00 83.39  ? 96  LEU M CG  1 
ATOM   6135 C CD1 . LEU E 3 97  ? -11.975 20.583  -36.869 1.00 81.82  ? 96  LEU M CD1 1 
ATOM   6136 C CD2 . LEU E 3 97  ? -13.722 18.825  -36.765 1.00 77.97  ? 96  LEU M CD2 1 
ATOM   6137 N N   . THR E 3 98  ? -17.237 19.669  -35.616 1.00 78.39  ? 97  THR M N   1 
ATOM   6138 C CA  . THR E 3 98  ? -18.185 18.593  -35.362 1.00 75.57  ? 97  THR M CA  1 
ATOM   6139 C C   . THR E 3 98  ? -18.250 17.636  -36.545 1.00 78.70  ? 97  THR M C   1 
ATOM   6140 O O   . THR E 3 98  ? -18.327 18.064  -37.701 1.00 77.56  ? 97  THR M O   1 
ATOM   6141 C CB  . THR E 3 98  ? -19.584 19.149  -35.067 1.00 82.20  ? 97  THR M CB  1 
ATOM   6142 O OG1 . THR E 3 98  ? -19.480 20.218  -34.120 1.00 87.82  ? 97  THR M OG1 1 
ATOM   6143 C CG2 . THR E 3 98  ? -20.477 18.060  -34.489 1.00 79.30  ? 97  THR M CG2 1 
ATOM   6144 N N   . PHE E 3 99  ? -18.238 16.341  -36.245 1.00 76.28  ? 98  PHE M N   1 
ATOM   6145 C CA  . PHE E 3 99  ? -18.411 15.295  -37.242 1.00 68.16  ? 98  PHE M CA  1 
ATOM   6146 C C   . PHE E 3 99  ? -19.830 14.743  -37.193 1.00 67.52  ? 98  PHE M C   1 
ATOM   6147 O O   . PHE E 3 99  ? -20.557 14.909  -36.211 1.00 76.00  ? 98  PHE M O   1 
ATOM   6148 C CB  . PHE E 3 99  ? -17.417 14.149  -37.025 1.00 68.86  ? 98  PHE M CB  1 
ATOM   6149 C CG  . PHE E 3 99  ? -15.988 14.512  -37.304 1.00 66.08  ? 98  PHE M CG  1 
ATOM   6150 C CD1 . PHE E 3 99  ? -15.463 14.376  -38.579 1.00 65.24  ? 98  PHE M CD1 1 
ATOM   6151 C CD2 . PHE E 3 99  ? -15.162 14.964  -36.290 1.00 62.52  ? 98  PHE M CD2 1 
ATOM   6152 C CE1 . PHE E 3 99  ? -14.144 14.700  -38.840 1.00 60.61  ? 98  PHE M CE1 1 
ATOM   6153 C CE2 . PHE E 3 99  ? -13.843 15.289  -36.543 1.00 65.40  ? 98  PHE M CE2 1 
ATOM   6154 C CZ  . PHE E 3 99  ? -13.334 15.157  -37.821 1.00 62.79  ? 98  PHE M CZ  1 
ATOM   6155 N N   . GLY E 3 100 ? -20.217 14.076  -38.279 1.00 66.70  ? 99  GLY M N   1 
ATOM   6156 C CA  . GLY E 3 100 ? -21.442 13.308  -38.292 1.00 67.03  ? 99  GLY M CA  1 
ATOM   6157 C C   . GLY E 3 100 ? -21.198 11.850  -37.949 1.00 65.18  ? 99  GLY M C   1 
ATOM   6158 O O   . GLY E 3 100 ? -20.063 11.379  -37.898 1.00 65.62  ? 99  GLY M O   1 
ATOM   6159 N N   . ALA E 3 101 ? -22.296 11.131  -37.709 1.00 61.02  ? 100 ALA M N   1 
ATOM   6160 C CA  . ALA E 3 101 ? -22.195 9.720   -37.357 1.00 59.40  ? 100 ALA M CA  1 
ATOM   6161 C C   . ALA E 3 101 ? -21.645 8.866   -38.490 1.00 58.95  ? 100 ALA M C   1 
ATOM   6162 O O   . ALA E 3 101 ? -21.291 7.706   -38.254 1.00 62.02  ? 100 ALA M O   1 
ATOM   6163 C CB  . ALA E 3 101 ? -23.563 9.184   -36.930 1.00 59.02  ? 100 ALA M CB  1 
ATOM   6164 N N   . GLY E 3 102 ? -21.563 9.404   -39.703 1.00 55.42  ? 101 GLY M N   1 
ATOM   6165 C CA  . GLY E 3 102 ? -21.035 8.652   -40.821 1.00 54.96  ? 101 GLY M CA  1 
ATOM   6166 C C   . GLY E 3 102 ? -22.077 7.756   -41.451 1.00 53.83  ? 101 GLY M C   1 
ATOM   6167 O O   . GLY E 3 102 ? -23.005 7.297   -40.778 1.00 61.75  ? 101 GLY M O   1 
ATOM   6168 N N   . THR E 3 103 ? -21.935 7.503   -42.747 1.00 46.83  ? 102 THR M N   1 
ATOM   6169 C CA  . THR E 3 103 ? -22.781 6.564   -43.466 1.00 50.23  ? 102 THR M CA  1 
ATOM   6170 C C   . THR E 3 103 ? -21.897 5.490   -44.077 1.00 53.00  ? 102 THR M C   1 
ATOM   6171 O O   . THR E 3 103 ? -20.910 5.805   -44.750 1.00 54.46  ? 102 THR M O   1 
ATOM   6172 C CB  . THR E 3 103 ? -23.597 7.266   -44.556 1.00 55.38  ? 102 THR M CB  1 
ATOM   6173 O OG1 . THR E 3 103 ? -24.637 8.047   -43.951 1.00 58.60  ? 102 THR M OG1 1 
ATOM   6174 C CG2 . THR E 3 103 ? -24.215 6.245   -45.504 1.00 55.46  ? 102 THR M CG2 1 
ATOM   6175 N N   . LYS E 3 104 ? -22.237 4.230   -43.824 1.00 49.63  ? 103 LYS M N   1 
ATOM   6176 C CA  . LYS E 3 104 ? -21.523 3.111   -44.417 1.00 50.86  ? 103 LYS M CA  1 
ATOM   6177 C C   . LYS E 3 104 ? -22.111 2.824   -45.791 1.00 51.31  ? 103 LYS M C   1 
ATOM   6178 O O   . LYS E 3 104 ? -23.312 2.564   -45.917 1.00 54.12  ? 103 LYS M O   1 
ATOM   6179 C CB  . LYS E 3 104 ? -21.606 1.866   -43.536 1.00 47.70  ? 103 LYS M CB  1 
ATOM   6180 C CG  . LYS E 3 104 ? -20.929 0.659   -44.165 1.00 42.75  ? 103 LYS M CG  1 
ATOM   6181 C CD  . LYS E 3 104 ? -21.017 -0.574  -43.287 1.00 52.56  ? 103 LYS M CD  1 
ATOM   6182 C CE  . LYS E 3 104 ? -20.329 -1.753  -43.956 1.00 50.03  ? 103 LYS M CE  1 
ATOM   6183 N NZ  . LYS E 3 104 ? -20.397 -2.987  -43.129 1.00 51.95  ? 103 LYS M NZ  1 
ATOM   6184 N N   . LEU E 3 105 ? -21.266 2.877   -46.813 1.00 48.76  ? 104 LEU M N   1 
ATOM   6185 C CA  . LEU E 3 105 ? -21.643 2.551   -48.179 1.00 45.81  ? 104 LEU M CA  1 
ATOM   6186 C C   . LEU E 3 105 ? -21.067 1.176   -48.489 1.00 48.68  ? 104 LEU M C   1 
ATOM   6187 O O   . LEU E 3 105 ? -19.847 1.025   -48.640 1.00 54.36  ? 104 LEU M O   1 
ATOM   6188 C CB  . LEU E 3 105 ? -21.122 3.615   -49.142 1.00 45.95  ? 104 LEU M CB  1 
ATOM   6189 C CG  . LEU E 3 105 ? -21.328 3.404   -50.637 1.00 51.54  ? 104 LEU M CG  1 
ATOM   6190 C CD1 . LEU E 3 105 ? -22.800 3.192   -50.927 1.00 52.76  ? 104 LEU M CD1 1 
ATOM   6191 C CD2 . LEU E 3 105 ? -20.788 4.604   -51.398 1.00 53.49  ? 104 LEU M CD2 1 
ATOM   6192 N N   . GLU E 3 106 ? -21.946 0.181   -48.571 1.00 45.26  ? 105 GLU M N   1 
ATOM   6193 C CA  . GLU E 3 106 ? -21.576 -1.212  -48.753 1.00 49.04  ? 105 GLU M CA  1 
ATOM   6194 C C   . GLU E 3 106 ? -22.009 -1.694  -50.130 1.00 51.36  ? 105 GLU M C   1 
ATOM   6195 O O   . GLU E 3 106 ? -22.858 -1.089  -50.788 1.00 55.43  ? 105 GLU M O   1 
ATOM   6196 C CB  . GLU E 3 106 ? -22.209 -2.093  -47.670 1.00 50.58  ? 105 GLU M CB  1 
ATOM   6197 C CG  . GLU E 3 106 ? -23.707 -2.307  -47.848 1.00 49.66  ? 105 GLU M CG  1 
ATOM   6198 C CD  . GLU E 3 106 ? -24.267 -3.347  -46.901 1.00 53.75  ? 105 GLU M CD  1 
ATOM   6199 O OE1 . GLU E 3 106 ? -23.575 -3.699  -45.924 1.00 47.55  ? 105 GLU M OE1 1 
ATOM   6200 O OE2 . GLU E 3 106 ? -25.402 -3.814  -47.132 1.00 48.57  ? 105 GLU M OE2 1 
ATOM   6201 N N   . LEU E 3 107 ? -21.407 -2.799  -50.560 1.00 44.44  ? 106 LEU M N   1 
ATOM   6202 C CA  . LEU E 3 107 ? -21.738 -3.394  -51.848 1.00 51.77  ? 106 LEU M CA  1 
ATOM   6203 C C   . LEU E 3 107 ? -22.961 -4.293  -51.693 1.00 52.01  ? 106 LEU M C   1 
ATOM   6204 O O   . LEU E 3 107 ? -22.968 -5.202  -50.855 1.00 48.62  ? 106 LEU M O   1 
ATOM   6205 C CB  . LEU E 3 107 ? -20.548 -4.178  -52.394 1.00 50.83  ? 106 LEU M CB  1 
ATOM   6206 C CG  . LEU E 3 107 ? -19.470 -3.308  -53.050 1.00 56.40  ? 106 LEU M CG  1 
ATOM   6207 C CD1 . LEU E 3 107 ? -18.258 -4.142  -53.447 1.00 56.09  ? 106 LEU M CD1 1 
ATOM   6208 C CD2 . LEU E 3 107 ? -20.009 -2.495  -54.221 1.00 56.25  ? 106 LEU M CD2 1 
ATOM   6209 N N   . LYS E 3 108 ? -23.995 -4.036  -52.490 1.00 52.89  ? 107 LYS M N   1 
ATOM   6210 C CA  . LYS E 3 108 ? -25.199 -4.853  -52.451 1.00 46.16  ? 107 LYS M CA  1 
ATOM   6211 C C   . LYS E 3 108 ? -25.027 -6.111  -53.292 1.00 43.12  ? 107 LYS M C   1 
ATOM   6212 O O   . LYS E 3 108 ? -24.415 -6.083  -54.364 1.00 49.14  ? 107 LYS M O   1 
ATOM   6213 C CB  . LYS E 3 108 ? -26.408 -4.053  -52.943 1.00 53.44  ? 107 LYS M CB  1 
ATOM   6214 C CG  . LYS E 3 108 ? -27.703 -4.853  -52.992 1.00 51.38  ? 107 LYS M CG  1 
ATOM   6215 C CD  . LYS E 3 108 ? -28.845 -4.048  -53.590 1.00 56.35  ? 107 LYS M CD  1 
ATOM   6216 C CE  . LYS E 3 108 ? -29.357 -3.003  -52.613 1.00 59.51  ? 107 LYS M CE  1 
ATOM   6217 N NZ  . LYS E 3 108 ? -30.543 -2.279  -53.145 1.00 56.16  ? 107 LYS M NZ  1 
ATOM   6218 N N   . ARG E 3 109 ? -25.569 -7.220  -52.794 1.00 36.33  ? 108 ARG M N   1 
ATOM   6219 C CA  . ARG E 3 109 ? -25.555 -8.492  -53.502 1.00 36.45  ? 108 ARG M CA  1 
ATOM   6220 C C   . ARG E 3 109 ? -26.931 -9.128  -53.342 1.00 38.97  ? 108 ARG M C   1 
ATOM   6221 O O   . ARG E 3 109 ? -27.864 -8.511  -52.819 1.00 36.77  ? 108 ARG M O   1 
ATOM   6222 C CB  . ARG E 3 109 ? -24.436 -9.403  -52.981 1.00 39.16  ? 108 ARG M CB  1 
ATOM   6223 C CG  . ARG E 3 109 ? -24.545 -9.715  -51.499 1.00 36.33  ? 108 ARG M CG  1 
ATOM   6224 C CD  . ARG E 3 109 ? -23.930 -11.061 -51.166 1.00 33.91  ? 108 ARG M CD  1 
ATOM   6225 N NE  . ARG E 3 109 ? -24.734 -12.166 -51.673 1.00 35.61  ? 108 ARG M NE  1 
ATOM   6226 C CZ  . ARG E 3 109 ? -24.277 -13.393 -51.879 1.00 39.52  ? 108 ARG M CZ  1 
ATOM   6227 N NH1 . ARG E 3 109 ? -23.012 -13.706 -51.656 1.00 36.17  ? 108 ARG M NH1 1 
ATOM   6228 N NH2 . ARG E 3 109 ? -25.111 -14.329 -52.325 1.00 37.80  ? 108 ARG M NH2 1 
ATOM   6229 N N   . THR E 3 110 ? -27.062 -10.373 -53.789 1.00 34.45  ? 109 THR M N   1 
ATOM   6230 C CA  . THR E 3 110 ? -28.322 -11.079 -53.634 1.00 33.32  ? 109 THR M CA  1 
ATOM   6231 C C   . THR E 3 110 ? -28.503 -11.539 -52.190 1.00 42.94  ? 109 THR M C   1 
ATOM   6232 O O   . THR E 3 110 ? -27.546 -11.658 -51.419 1.00 39.49  ? 109 THR M O   1 
ATOM   6233 C CB  . THR E 3 110 ? -28.398 -12.275 -54.585 1.00 34.03  ? 109 THR M CB  1 
ATOM   6234 O OG1 . THR E 3 110 ? -27.285 -13.148 -54.354 1.00 33.38  ? 109 THR M OG1 1 
ATOM   6235 C CG2 . THR E 3 110 ? -28.381 -11.805 -56.035 1.00 38.46  ? 109 THR M CG2 1 
ATOM   6236 N N   . VAL E 3 111 ? -29.759 -11.797 -51.828 1.00 37.53  ? 110 VAL M N   1 
ATOM   6237 C CA  . VAL E 3 111 ? -30.086 -12.193 -50.464 1.00 30.33  ? 110 VAL M CA  1 
ATOM   6238 C C   . VAL E 3 111 ? -29.533 -13.584 -50.189 1.00 33.99  ? 110 VAL M C   1 
ATOM   6239 O O   . VAL E 3 111 ? -29.675 -14.502 -51.007 1.00 37.73  ? 110 VAL M O   1 
ATOM   6240 C CB  . VAL E 3 111 ? -31.604 -12.142 -50.238 1.00 33.28  ? 110 VAL M CB  1 
ATOM   6241 C CG1 . VAL E 3 111 ? -31.958 -12.663 -48.854 1.00 28.93  ? 110 VAL M CG1 1 
ATOM   6242 C CG2 . VAL E 3 111 ? -32.118 -10.728 -50.427 1.00 30.14  ? 110 VAL M CG2 1 
ATOM   6243 N N   . ALA E 3 112 ? -28.895 -13.745 -49.031 1.00 37.63  ? 111 ALA M N   1 
ATOM   6244 C CA  . ALA E 3 112 ? -28.382 -15.037 -48.593 1.00 35.14  ? 111 ALA M CA  1 
ATOM   6245 C C   . ALA E 3 112 ? -28.738 -15.233 -47.129 1.00 30.73  ? 111 ALA M C   1 
ATOM   6246 O O   . ALA E 3 112 ? -28.295 -14.461 -46.274 1.00 29.58  ? 111 ALA M O   1 
ATOM   6247 C CB  . ALA E 3 112 ? -26.867 -15.128 -48.796 1.00 31.27  ? 111 ALA M CB  1 
ATOM   6248 N N   . ALA E 3 113 ? -29.549 -16.248 -46.846 1.00 36.79  ? 112 ALA M N   1 
ATOM   6249 C CA  . ALA E 3 113 ? -29.874 -16.572 -45.469 1.00 32.79  ? 112 ALA M CA  1 
ATOM   6250 C C   . ALA E 3 113 ? -28.649 -17.157 -44.766 1.00 33.11  ? 112 ALA M C   1 
ATOM   6251 O O   . ALA E 3 113 ? -27.844 -17.858 -45.386 1.00 34.80  ? 112 ALA M O   1 
ATOM   6252 C CB  . ALA E 3 113 ? -31.036 -17.560 -45.410 1.00 29.56  ? 112 ALA M CB  1 
ATOM   6253 N N   . PRO E 3 114 ? -28.482 -16.882 -43.474 1.00 36.31  ? 113 PRO M N   1 
ATOM   6254 C CA  . PRO E 3 114 ? -27.306 -17.393 -42.762 1.00 34.41  ? 113 PRO M CA  1 
ATOM   6255 C C   . PRO E 3 114 ? -27.372 -18.898 -42.565 1.00 35.25  ? 113 PRO M C   1 
ATOM   6256 O O   . PRO E 3 114 ? -28.450 -19.487 -42.448 1.00 32.23  ? 113 PRO M O   1 
ATOM   6257 C CB  . PRO E 3 114 ? -27.362 -16.659 -41.417 1.00 33.23  ? 113 PRO M CB  1 
ATOM   6258 C CG  . PRO E 3 114 ? -28.812 -16.359 -41.223 1.00 36.79  ? 113 PRO M CG  1 
ATOM   6259 C CD  . PRO E 3 114 ? -29.359 -16.085 -42.597 1.00 36.25  ? 113 PRO M CD  1 
ATOM   6260 N N   . SER E 3 115 ? -26.197 -19.522 -42.529 1.00 39.90  ? 114 SER M N   1 
ATOM   6261 C CA  . SER E 3 115 ? -26.084 -20.901 -42.071 1.00 38.91  ? 114 SER M CA  1 
ATOM   6262 C C   . SER E 3 115 ? -25.827 -20.881 -40.569 1.00 32.76  ? 114 SER M C   1 
ATOM   6263 O O   . SER E 3 115 ? -24.873 -20.246 -40.112 1.00 31.71  ? 114 SER M O   1 
ATOM   6264 C CB  . SER E 3 115 ? -24.966 -21.635 -42.810 1.00 33.69  ? 114 SER M CB  1 
ATOM   6265 O OG  . SER E 3 115 ? -25.298 -21.823 -44.175 1.00 49.84  ? 114 SER M OG  1 
ATOM   6266 N N   . VAL E 3 116 ? -26.672 -21.562 -39.803 1.00 39.03  ? 115 VAL M N   1 
ATOM   6267 C CA  . VAL E 3 116 ? -26.630 -21.486 -38.347 1.00 33.57  ? 115 VAL M CA  1 
ATOM   6268 C C   . VAL E 3 116 ? -26.007 -22.759 -37.793 1.00 39.76  ? 115 VAL M C   1 
ATOM   6269 O O   . VAL E 3 116 ? -26.400 -23.871 -38.168 1.00 37.87  ? 115 VAL M O   1 
ATOM   6270 C CB  . VAL E 3 116 ? -28.030 -21.254 -37.756 1.00 35.67  ? 115 VAL M CB  1 
ATOM   6271 C CG1 . VAL E 3 116 ? -27.928 -20.945 -36.271 1.00 32.48  ? 115 VAL M CG1 1 
ATOM   6272 C CG2 . VAL E 3 116 ? -28.732 -20.121 -38.488 1.00 35.50  ? 115 VAL M CG2 1 
ATOM   6273 N N   . PHE E 3 117 ? -25.034 -22.593 -36.902 1.00 34.19  ? 116 PHE M N   1 
ATOM   6274 C CA  . PHE E 3 117 ? -24.401 -23.700 -36.200 1.00 32.42  ? 116 PHE M CA  1 
ATOM   6275 C C   . PHE E 3 117 ? -24.316 -23.364 -34.718 1.00 39.83  ? 116 PHE M C   1 
ATOM   6276 O O   . PHE E 3 117 ? -24.252 -22.194 -34.338 1.00 39.15  ? 116 PHE M O   1 
ATOM   6277 C CB  . PHE E 3 117 ? -22.995 -24.002 -36.745 1.00 36.18  ? 116 PHE M CB  1 
ATOM   6278 C CG  . PHE E 3 117 ? -22.944 -24.194 -38.236 1.00 38.41  ? 116 PHE M CG  1 
ATOM   6279 C CD1 . PHE E 3 117 ? -22.771 -23.113 -39.086 1.00 37.50  ? 116 PHE M CD1 1 
ATOM   6280 C CD2 . PHE E 3 117 ? -23.058 -25.461 -38.786 1.00 38.55  ? 116 PHE M CD2 1 
ATOM   6281 C CE1 . PHE E 3 117 ? -22.720 -23.292 -40.457 1.00 42.28  ? 116 PHE M CE1 1 
ATOM   6282 C CE2 . PHE E 3 117 ? -23.006 -25.645 -40.156 1.00 44.00  ? 116 PHE M CE2 1 
ATOM   6283 C CZ  . PHE E 3 117 ? -22.838 -24.560 -40.993 1.00 43.00  ? 116 PHE M CZ  1 
ATOM   6284 N N   . ILE E 3 118 ? -24.330 -24.395 -33.876 1.00 36.83  ? 117 ILE M N   1 
ATOM   6285 C CA  . ILE E 3 118 ? -24.217 -24.213 -32.434 1.00 36.29  ? 117 ILE M CA  1 
ATOM   6286 C C   . ILE E 3 118 ? -23.126 -25.132 -31.899 1.00 36.83  ? 117 ILE M C   1 
ATOM   6287 O O   . ILE E 3 118 ? -22.937 -26.251 -32.390 1.00 33.90  ? 117 ILE M O   1 
ATOM   6288 C CB  . ILE E 3 118 ? -25.562 -24.454 -31.711 1.00 43.57  ? 117 ILE M CB  1 
ATOM   6289 C CG1 . ILE E 3 118 ? -25.491 -23.948 -30.267 1.00 36.24  ? 117 ILE M CG1 1 
ATOM   6290 C CG2 . ILE E 3 118 ? -25.962 -25.922 -31.756 1.00 43.24  ? 117 ILE M CG2 1 
ATOM   6291 C CD1 . ILE E 3 118 ? -26.823 -23.950 -29.550 1.00 36.24  ? 117 ILE M CD1 1 
ATOM   6292 N N   . PHE E 3 119 ? -22.390 -24.638 -30.905 1.00 34.04  ? 118 PHE M N   1 
ATOM   6293 C CA  . PHE E 3 119 ? -21.269 -25.346 -30.300 1.00 37.12  ? 118 PHE M CA  1 
ATOM   6294 C C   . PHE E 3 119 ? -21.480 -25.350 -28.797 1.00 34.00  ? 118 PHE M C   1 
ATOM   6295 O O   . PHE E 3 119 ? -21.593 -24.262 -28.182 1.00 38.48  ? 118 PHE M O   1 
ATOM   6296 C CB  . PHE E 3 119 ? -19.936 -24.680 -30.651 1.00 36.65  ? 118 PHE M CB  1 
ATOM   6297 C CG  . PHE E 3 119 ? -19.700 -24.520 -32.121 1.00 38.44  ? 118 PHE M CG  1 
ATOM   6298 C CD1 . PHE E 3 119 ? -19.247 -25.582 -32.884 1.00 37.40  ? 118 PHE M CD1 1 
ATOM   6299 C CD2 . PHE E 3 119 ? -19.920 -23.302 -32.740 1.00 31.42  ? 118 PHE M CD2 1 
ATOM   6300 C CE1 . PHE E 3 119 ? -19.024 -25.434 -34.240 1.00 42.08  ? 118 PHE M CE1 1 
ATOM   6301 C CE2 . PHE E 3 119 ? -19.700 -23.145 -34.094 1.00 36.85  ? 118 PHE M CE2 1 
ATOM   6302 C CZ  . PHE E 3 119 ? -19.252 -24.213 -34.845 1.00 38.75  ? 118 PHE M CZ  1 
ATOM   6303 N N   . PRO E 3 120 ? -21.541 -26.518 -28.160 1.00 41.47  ? 119 PRO M N   1 
ATOM   6304 C CA  . PRO E 3 120 ? -21.635 -26.581 -26.703 1.00 38.23  ? 119 PRO M CA  1 
ATOM   6305 C C   . PRO E 3 120 ? -20.287 -26.286 -26.070 1.00 41.12  ? 119 PRO M C   1 
ATOM   6306 O O   . PRO E 3 120 ? -19.256 -26.303 -26.758 1.00 38.89  ? 119 PRO M O   1 
ATOM   6307 C CB  . PRO E 3 120 ? -22.069 -28.034 -26.436 1.00 44.47  ? 119 PRO M CB  1 
ATOM   6308 C CG  . PRO E 3 120 ? -22.410 -28.621 -27.787 1.00 35.72  ? 119 PRO M CG  1 
ATOM   6309 C CD  . PRO E 3 120 ? -21.601 -27.854 -28.773 1.00 34.36  ? 119 PRO M CD  1 
ATOM   6310 N N   . PRO E 3 121 ? -20.249 -26.008 -24.768 1.00 40.94  ? 120 PRO M N   1 
ATOM   6311 C CA  . PRO E 3 121 ? -18.959 -25.789 -24.107 1.00 40.70  ? 120 PRO M CA  1 
ATOM   6312 C C   . PRO E 3 121 ? -18.117 -27.055 -24.084 1.00 46.48  ? 120 PRO M C   1 
ATOM   6313 O O   . PRO E 3 121 ? -18.629 -28.177 -24.098 1.00 50.61  ? 120 PRO M O   1 
ATOM   6314 C CB  . PRO E 3 121 ? -19.352 -25.360 -22.688 1.00 44.17  ? 120 PRO M CB  1 
ATOM   6315 C CG  . PRO E 3 121 ? -20.733 -25.891 -22.497 1.00 41.68  ? 120 PRO M CG  1 
ATOM   6316 C CD  . PRO E 3 121 ? -21.381 -25.824 -23.844 1.00 42.78  ? 120 PRO M CD  1 
ATOM   6317 N N   . SER E 3 122 ? -16.803 -26.858 -24.052 1.00 48.37  ? 121 SER M N   1 
ATOM   6318 C CA  . SER E 3 122 ? -15.875 -27.973 -23.971 1.00 51.87  ? 121 SER M CA  1 
ATOM   6319 C C   . SER E 3 122 ? -15.705 -28.418 -22.522 1.00 49.86  ? 121 SER M C   1 
ATOM   6320 O O   . SER E 3 122 ? -16.054 -27.702 -21.579 1.00 45.32  ? 121 SER M O   1 
ATOM   6321 C CB  . SER E 3 122 ? -14.521 -27.591 -24.568 1.00 48.84  ? 121 SER M CB  1 
ATOM   6322 O OG  . SER E 3 122 ? -13.946 -26.498 -23.872 1.00 49.24  ? 121 SER M OG  1 
ATOM   6323 N N   . ASP E 3 123 ? -15.164 -29.626 -22.353 1.00 55.39  ? 122 ASP M N   1 
ATOM   6324 C CA  . ASP E 3 123 ? -14.892 -30.126 -21.008 1.00 59.33  ? 122 ASP M CA  1 
ATOM   6325 C C   . ASP E 3 123 ? -13.801 -29.311 -20.325 1.00 58.60  ? 122 ASP M C   1 
ATOM   6326 O O   . ASP E 3 123 ? -13.849 -29.097 -19.107 1.00 55.14  ? 122 ASP M O   1 
ATOM   6327 C CB  . ASP E 3 123 ? -14.501 -31.603 -21.064 1.00 62.75  ? 122 ASP M CB  1 
ATOM   6328 C CG  . ASP E 3 123 ? -15.630 -32.488 -21.556 1.00 64.77  ? 122 ASP M CG  1 
ATOM   6329 O OD1 . ASP E 3 123 ? -16.610 -32.678 -20.804 1.00 65.60  ? 122 ASP M OD1 1 
ATOM   6330 O OD2 . ASP E 3 123 ? -15.533 -33.002 -22.690 1.00 68.01  ? 122 ASP M OD2 1 
ATOM   6331 N N   . GLU E 3 124 ? -12.807 -28.857 -21.093 1.00 59.35  ? 123 GLU M N   1 
ATOM   6332 C CA  . GLU E 3 124 ? -11.722 -28.058 -20.530 1.00 52.82  ? 123 GLU M CA  1 
ATOM   6333 C C   . GLU E 3 124 ? -12.253 -26.801 -19.853 1.00 52.87  ? 123 GLU M C   1 
ATOM   6334 O O   . GLU E 3 124 ? -11.851 -26.467 -18.732 1.00 59.60  ? 123 GLU M O   1 
ATOM   6335 C CB  . GLU E 3 124 ? -10.714 -27.696 -21.624 1.00 54.18  ? 123 GLU M CB  1 
ATOM   6336 C CG  . GLU E 3 124 ? -10.089 -28.885 -22.354 1.00 56.48  ? 123 GLU M CG  1 
ATOM   6337 C CD  . GLU E 3 124 ? -10.972 -29.451 -23.456 1.00 63.43  ? 123 GLU M CD  1 
ATOM   6338 O OE1 . GLU E 3 124 ? -12.209 -29.478 -23.290 1.00 61.30  ? 123 GLU M OE1 1 
ATOM   6339 O OE2 . GLU E 3 124 ? -10.424 -29.871 -24.496 1.00 59.90  ? 123 GLU M OE2 1 
ATOM   6340 N N   . GLN E 3 125 ? -13.162 -26.086 -20.521 1.00 52.65  ? 124 GLN M N   1 
ATOM   6341 C CA  . GLN E 3 125 ? -13.718 -24.877 -19.926 1.00 47.21  ? 124 GLN M CA  1 
ATOM   6342 C C   . GLN E 3 125 ? -14.635 -25.208 -18.756 1.00 45.42  ? 124 GLN M C   1 
ATOM   6343 O O   . GLN E 3 125 ? -14.688 -24.453 -17.777 1.00 48.06  ? 124 GLN M O   1 
ATOM   6344 C CB  . GLN E 3 125 ? -14.471 -24.065 -20.977 1.00 44.24  ? 124 GLN M CB  1 
ATOM   6345 C CG  . GLN E 3 125 ? -14.912 -22.698 -20.487 1.00 43.56  ? 124 GLN M CG  1 
ATOM   6346 C CD  . GLN E 3 125 ? -15.896 -22.029 -21.423 1.00 44.54  ? 124 GLN M CD  1 
ATOM   6347 O OE1 . GLN E 3 125 ? -16.433 -22.660 -22.333 1.00 39.28  ? 124 GLN M OE1 1 
ATOM   6348 N NE2 . GLN E 3 125 ? -16.144 -20.745 -21.198 1.00 43.25  ? 124 GLN M NE2 1 
ATOM   6349 N N   . LEU E 3 126 ? -15.361 -26.325 -18.840 1.00 49.15  ? 125 LEU M N   1 
ATOM   6350 C CA  . LEU E 3 126 ? -16.252 -26.715 -17.755 1.00 56.92  ? 125 LEU M CA  1 
ATOM   6351 C C   . LEU E 3 126 ? -15.473 -27.053 -16.491 1.00 51.00  ? 125 LEU M C   1 
ATOM   6352 O O   . LEU E 3 126 ? -15.973 -26.834 -15.381 1.00 54.42  ? 125 LEU M O   1 
ATOM   6353 C CB  . LEU E 3 126 ? -17.125 -27.894 -18.185 1.00 55.96  ? 125 LEU M CB  1 
ATOM   6354 C CG  . LEU E 3 126 ? -18.252 -27.549 -19.161 1.00 49.72  ? 125 LEU M CG  1 
ATOM   6355 C CD1 . LEU E 3 126 ? -18.988 -28.801 -19.607 1.00 52.19  ? 125 LEU M CD1 1 
ATOM   6356 C CD2 . LEU E 3 126 ? -19.215 -26.547 -18.538 1.00 37.17  ? 125 LEU M CD2 1 
ATOM   6357 N N   . LYS E 3 127 ? -14.256 -27.591 -16.633 1.00 52.57  ? 126 LYS M N   1 
ATOM   6358 C CA  . LYS E 3 127 ? -13.422 -27.844 -15.462 1.00 56.36  ? 126 LYS M CA  1 
ATOM   6359 C C   . LYS E 3 127 ? -13.071 -26.566 -14.714 1.00 58.28  ? 126 LYS M C   1 
ATOM   6360 O O   . LYS E 3 127 ? -12.681 -26.634 -13.543 1.00 65.37  ? 126 LYS M O   1 
ATOM   6361 C CB  . LYS E 3 127 ? -12.118 -28.538 -15.865 1.00 55.72  ? 126 LYS M CB  1 
ATOM   6362 C CG  . LYS E 3 127 ? -12.264 -29.919 -16.464 1.00 59.06  ? 126 LYS M CG  1 
ATOM   6363 C CD  . LYS E 3 127 ? -10.901 -30.461 -16.875 1.00 59.08  ? 126 LYS M CD  1 
ATOM   6364 C CE  . LYS E 3 127 ? -9.975  -30.606 -15.676 1.00 62.56  ? 126 LYS M CE  1 
ATOM   6365 N NZ  . LYS E 3 127 ? -8.637  -31.139 -16.060 1.00 56.99  ? 126 LYS M NZ  1 
ATOM   6366 N N   . SER E 3 128 ? -13.203 -25.405 -15.355 1.00 52.73  ? 127 SER M N   1 
ATOM   6367 C CA  . SER E 3 128 ? -12.885 -24.127 -14.734 1.00 45.76  ? 127 SER M CA  1 
ATOM   6368 C C   . SER E 3 128 ? -14.099 -23.421 -14.146 1.00 48.78  ? 127 SER M C   1 
ATOM   6369 O O   . SER E 3 128 ? -13.935 -22.375 -13.508 1.00 52.80  ? 127 SER M O   1 
ATOM   6370 C CB  . SER E 3 128 ? -12.201 -23.203 -15.750 1.00 57.09  ? 127 SER M CB  1 
ATOM   6371 O OG  . SER E 3 128 ? -13.156 -22.551 -16.568 1.00 51.83  ? 127 SER M OG  1 
ATOM   6372 N N   . GLY E 3 129 ? -15.301 -23.953 -14.343 1.00 52.55  ? 128 GLY M N   1 
ATOM   6373 C CA  . GLY E 3 129 ? -16.484 -23.377 -13.740 1.00 50.94  ? 128 GLY M CA  1 
ATOM   6374 C C   . GLY E 3 129 ? -17.237 -22.396 -14.607 1.00 48.98  ? 128 GLY M C   1 
ATOM   6375 O O   . GLY E 3 129 ? -17.959 -21.548 -14.071 1.00 44.80  ? 128 GLY M O   1 
ATOM   6376 N N   . THR E 3 130 ? -17.098 -22.481 -15.928 1.00 49.96  ? 129 THR M N   1 
ATOM   6377 C CA  . THR E 3 130 ? -17.783 -21.572 -16.834 1.00 50.28  ? 129 THR M CA  1 
ATOM   6378 C C   . THR E 3 130 ? -18.136 -22.324 -18.108 1.00 44.05  ? 129 THR M C   1 
ATOM   6379 O O   . THR E 3 130 ? -17.366 -23.171 -18.570 1.00 40.91  ? 129 THR M O   1 
ATOM   6380 C CB  . THR E 3 130 ? -16.914 -20.347 -17.156 1.00 50.68  ? 129 THR M CB  1 
ATOM   6381 O OG1 . THR E 3 130 ? -16.503 -19.718 -15.936 1.00 55.82  ? 129 THR M OG1 1 
ATOM   6382 C CG2 . THR E 3 130 ? -17.685 -19.340 -17.993 1.00 49.44  ? 129 THR M CG2 1 
ATOM   6383 N N   . ALA E 3 131 ? -19.308 -22.020 -18.661 1.00 44.19  ? 130 ALA M N   1 
ATOM   6384 C CA  . ALA E 3 131 ? -19.805 -22.647 -19.878 1.00 40.81  ? 130 ALA M CA  1 
ATOM   6385 C C   . ALA E 3 131 ? -20.083 -21.562 -20.906 1.00 39.84  ? 130 ALA M C   1 
ATOM   6386 O O   . ALA E 3 131 ? -20.911 -20.673 -20.668 1.00 38.18  ? 130 ALA M O   1 
ATOM   6387 C CB  . ALA E 3 131 ? -21.067 -23.466 -19.603 1.00 39.81  ? 130 ALA M CB  1 
ATOM   6388 N N   . SER E 3 132 ? -19.384 -21.629 -22.035 1.00 37.29  ? 131 SER M N   1 
ATOM   6389 C CA  . SER E 3 132 ? -19.608 -20.737 -23.165 1.00 39.50  ? 131 SER M CA  1 
ATOM   6390 C C   . SER E 3 132 ? -20.234 -21.540 -24.297 1.00 37.20  ? 131 SER M C   1 
ATOM   6391 O O   . SER E 3 132 ? -19.633 -22.502 -24.788 1.00 34.00  ? 131 SER M O   1 
ATOM   6392 C CB  . SER E 3 132 ? -18.303 -20.085 -23.621 1.00 35.22  ? 131 SER M CB  1 
ATOM   6393 O OG  . SER E 3 132 ? -17.760 -19.262 -22.604 1.00 39.46  ? 131 SER M OG  1 
ATOM   6394 N N   . VAL E 3 133 ? -21.439 -21.148 -24.700 1.00 36.60  ? 132 VAL M N   1 
ATOM   6395 C CA  . VAL E 3 133 ? -22.148 -21.750 -25.822 1.00 39.08  ? 132 VAL M CA  1 
ATOM   6396 C C   . VAL E 3 133 ? -22.069 -20.777 -26.987 1.00 33.48  ? 132 VAL M C   1 
ATOM   6397 O O   . VAL E 3 133 ? -22.361 -19.585 -26.825 1.00 32.91  ? 132 VAL M O   1 
ATOM   6398 C CB  . VAL E 3 133 ? -23.610 -22.063 -25.460 1.00 35.50  ? 132 VAL M CB  1 
ATOM   6399 C CG1 . VAL E 3 133 ? -24.255 -22.916 -26.538 1.00 34.15  ? 132 VAL M CG1 1 
ATOM   6400 C CG2 . VAL E 3 133 ? -23.687 -22.747 -24.102 1.00 41.52  ? 132 VAL M CG2 1 
ATOM   6401 N N   . VAL E 3 134 ? -21.678 -21.272 -28.159 1.00 33.77  ? 133 VAL M N   1 
ATOM   6402 C CA  . VAL E 3 134 ? -21.382 -20.403 -29.295 1.00 32.38  ? 133 VAL M CA  1 
ATOM   6403 C C   . VAL E 3 134 ? -22.374 -20.677 -30.416 1.00 32.09  ? 133 VAL M C   1 
ATOM   6404 O O   . VAL E 3 134 ? -22.612 -21.833 -30.774 1.00 35.33  ? 133 VAL M O   1 
ATOM   6405 C CB  . VAL E 3 134 ? -19.932 -20.584 -29.779 1.00 30.30  ? 133 VAL M CB  1 
ATOM   6406 C CG1 . VAL E 3 134 ? -19.666 -19.726 -31.004 1.00 29.91  ? 133 VAL M CG1 1 
ATOM   6407 C CG2 . VAL E 3 134 ? -18.964 -20.223 -28.663 1.00 32.18  ? 133 VAL M CG2 1 
ATOM   6408 N N   . CYS E 3 135 ? -22.953 -19.613 -30.966 1.00 32.89  ? 134 CYS M N   1 
ATOM   6409 C CA  . CYS E 3 135 ? -23.853 -19.694 -32.106 1.00 35.39  ? 134 CYS M CA  1 
ATOM   6410 C C   . CYS E 3 135 ? -23.242 -18.913 -33.260 1.00 33.67  ? 134 CYS M C   1 
ATOM   6411 O O   . CYS E 3 135 ? -22.898 -17.734 -33.107 1.00 31.57  ? 134 CYS M O   1 
ATOM   6412 C CB  . CYS E 3 135 ? -25.242 -19.150 -31.751 1.00 33.68  ? 134 CYS M CB  1 
ATOM   6413 S SG  . CYS E 3 135 ? -26.523 -19.320 -33.031 1.00 43.32  ? 134 CYS M SG  1 
ATOM   6414 N N   . LEU E 3 136 ? -23.103 -19.573 -34.406 1.00 35.66  ? 135 LEU M N   1 
ATOM   6415 C CA  . LEU E 3 136 ? -22.476 -19.005 -35.589 1.00 33.83  ? 135 LEU M CA  1 
ATOM   6416 C C   . LEU E 3 136 ? -23.514 -18.818 -36.685 1.00 36.43  ? 135 LEU M C   1 
ATOM   6417 O O   . LEU E 3 136 ? -24.236 -19.763 -37.028 1.00 35.67  ? 135 LEU M O   1 
ATOM   6418 C CB  . LEU E 3 136 ? -21.348 -19.905 -36.097 1.00 32.44  ? 135 LEU M CB  1 
ATOM   6419 C CG  . LEU E 3 136 ? -20.797 -19.540 -37.479 1.00 35.21  ? 135 LEU M CG  1 
ATOM   6420 C CD1 . LEU E 3 136 ? -20.078 -18.200 -37.442 1.00 31.90  ? 135 LEU M CD1 1 
ATOM   6421 C CD2 . LEU E 3 136 ? -19.891 -20.639 -38.017 1.00 34.44  ? 135 LEU M CD2 1 
ATOM   6422 N N   . LEU E 3 137 ? -23.576 -17.603 -37.231 1.00 34.61  ? 136 LEU M N   1 
ATOM   6423 C CA  . LEU E 3 137 ? -24.363 -17.278 -38.414 1.00 33.42  ? 136 LEU M CA  1 
ATOM   6424 C C   . LEU E 3 137 ? -23.365 -17.006 -39.534 1.00 32.92  ? 136 LEU M C   1 
ATOM   6425 O O   . LEU E 3 137 ? -22.636 -16.009 -39.492 1.00 33.11  ? 136 LEU M O   1 
ATOM   6426 C CB  . LEU E 3 137 ? -25.261 -16.066 -38.168 1.00 32.20  ? 136 LEU M CB  1 
ATOM   6427 C CG  . LEU E 3 137 ? -26.493 -16.161 -37.261 1.00 36.79  ? 136 LEU M CG  1 
ATOM   6428 C CD1 . LEU E 3 137 ? -26.138 -16.477 -35.812 1.00 35.47  ? 136 LEU M CD1 1 
ATOM   6429 C CD2 . LEU E 3 137 ? -27.279 -14.860 -37.346 1.00 27.71  ? 136 LEU M CD2 1 
ATOM   6430 N N   . ASN E 3 138 ? -23.332 -17.885 -40.529 1.00 32.80  ? 137 ASN M N   1 
ATOM   6431 C CA  . ASN E 3 138 ? -22.285 -17.892 -41.539 1.00 32.45  ? 137 ASN M CA  1 
ATOM   6432 C C   . ASN E 3 138 ? -22.832 -17.406 -42.872 1.00 34.89  ? 137 ASN M C   1 
ATOM   6433 O O   . ASN E 3 138 ? -23.839 -17.931 -43.366 1.00 34.95  ? 137 ASN M O   1 
ATOM   6434 C CB  . ASN E 3 138 ? -21.687 -19.292 -41.695 1.00 31.50  ? 137 ASN M CB  1 
ATOM   6435 C CG  . ASN E 3 138 ? -20.407 -19.293 -42.504 1.00 41.35  ? 137 ASN M CG  1 
ATOM   6436 O OD1 . ASN E 3 138 ? -20.411 -19.604 -43.694 1.00 47.87  ? 137 ASN M OD1 1 
ATOM   6437 N ND2 . ASN E 3 138 ? -19.300 -18.938 -41.861 1.00 38.52  ? 137 ASN M ND2 1 
ATOM   6438 N N   . ASN E 3 139 ? -22.175 -16.383 -43.425 1.00 34.54  ? 138 ASN M N   1 
ATOM   6439 C CA  . ASN E 3 139 ? -22.307 -15.958 -44.818 1.00 36.83  ? 138 ASN M CA  1 
ATOM   6440 C C   . ASN E 3 139 ? -23.757 -15.601 -45.161 1.00 33.92  ? 138 ASN M C   1 
ATOM   6441 O O   . ASN E 3 139 ? -24.450 -16.303 -45.900 1.00 32.13  ? 138 ASN M O   1 
ATOM   6442 C CB  . ASN E 3 139 ? -21.758 -17.035 -45.759 1.00 33.41  ? 138 ASN M CB  1 
ATOM   6443 C CG  . ASN E 3 139 ? -20.272 -17.269 -45.568 1.00 37.86  ? 138 ASN M CG  1 
ATOM   6444 O OD1 . ASN E 3 139 ? -19.573 -16.441 -44.987 1.00 35.47  ? 138 ASN M OD1 1 
ATOM   6445 N ND2 . ASN E 3 139 ? -19.784 -18.406 -46.052 1.00 39.42  ? 138 ASN M ND2 1 
ATOM   6446 N N   . PHE E 3 140 ? -24.193 -14.473 -44.607 1.00 30.84  ? 139 PHE M N   1 
ATOM   6447 C CA  . PHE E 3 140 ? -25.530 -13.966 -44.866 1.00 31.11  ? 139 PHE M CA  1 
ATOM   6448 C C   . PHE E 3 140 ? -25.466 -12.533 -45.375 1.00 29.61  ? 139 PHE M C   1 
ATOM   6449 O O   . PHE E 3 140 ? -24.477 -11.820 -45.186 1.00 30.76  ? 139 PHE M O   1 
ATOM   6450 C CB  . PHE E 3 140 ? -26.429 -14.047 -43.621 1.00 32.73  ? 139 PHE M CB  1 
ATOM   6451 C CG  . PHE E 3 140 ? -25.923 -13.267 -42.439 1.00 33.78  ? 139 PHE M CG  1 
ATOM   6452 C CD1 . PHE E 3 140 ? -25.030 -13.840 -41.549 1.00 32.19  ? 139 PHE M CD1 1 
ATOM   6453 C CD2 . PHE E 3 140 ? -26.360 -11.974 -42.202 1.00 28.28  ? 139 PHE M CD2 1 
ATOM   6454 C CE1 . PHE E 3 140 ? -24.569 -13.135 -40.453 1.00 27.03  ? 139 PHE M CE1 1 
ATOM   6455 C CE2 . PHE E 3 140 ? -25.900 -11.260 -41.109 1.00 35.33  ? 139 PHE M CE2 1 
ATOM   6456 C CZ  . PHE E 3 140 ? -25.004 -11.843 -40.233 1.00 26.73  ? 139 PHE M CZ  1 
ATOM   6457 N N   . TYR E 3 141 ? -26.554 -12.126 -46.034 1.00 32.76  ? 140 TYR M N   1 
ATOM   6458 C CA  . TYR E 3 141 ? -26.744 -10.770 -46.525 1.00 36.23  ? 140 TYR M CA  1 
ATOM   6459 C C   . TYR E 3 141 ? -28.229 -10.586 -46.777 1.00 29.96  ? 140 TYR M C   1 
ATOM   6460 O O   . TYR E 3 141 ? -28.868 -11.511 -47.298 1.00 33.01  ? 140 TYR M O   1 
ATOM   6461 C CB  . TYR E 3 141 ? -25.950 -10.503 -47.809 1.00 31.23  ? 140 TYR M CB  1 
ATOM   6462 C CG  . TYR E 3 141 ? -26.026 -9.063  -48.259 1.00 35.33  ? 140 TYR M CG  1 
ATOM   6463 C CD1 . TYR E 3 141 ? -25.164 -8.109  -47.737 1.00 31.09  ? 140 TYR M CD1 1 
ATOM   6464 C CD2 . TYR E 3 141 ? -26.980 -8.649  -49.182 1.00 36.78  ? 140 TYR M CD2 1 
ATOM   6465 C CE1 . TYR E 3 141 ? -25.234 -6.788  -48.132 1.00 43.72  ? 140 TYR M CE1 1 
ATOM   6466 C CE2 . TYR E 3 141 ? -27.059 -7.327  -49.583 1.00 32.51  ? 140 TYR M CE2 1 
ATOM   6467 C CZ  . TYR E 3 141 ? -26.182 -6.402  -49.053 1.00 37.49  ? 140 TYR M CZ  1 
ATOM   6468 O OH  . TYR E 3 141 ? -26.255 -5.087  -49.449 1.00 38.01  ? 140 TYR M OH  1 
ATOM   6469 N N   . PRO E 3 142 ? -28.812 -9.427  -46.440 1.00 30.19  ? 141 PRO M N   1 
ATOM   6470 C CA  . PRO E 3 142 ? -28.188 -8.233  -45.843 1.00 36.28  ? 141 PRO M CA  1 
ATOM   6471 C C   . PRO E 3 142 ? -27.744 -8.407  -44.390 1.00 36.03  ? 141 PRO M C   1 
ATOM   6472 O O   . PRO E 3 142 ? -27.863 -9.479  -43.803 1.00 35.58  ? 141 PRO M O   1 
ATOM   6473 C CB  . PRO E 3 142 ? -29.294 -7.175  -45.974 1.00 37.98  ? 141 PRO M CB  1 
ATOM   6474 C CG  . PRO E 3 142 ? -30.566 -7.962  -45.931 1.00 38.59  ? 141 PRO M CG  1 
ATOM   6475 C CD  . PRO E 3 142 ? -30.252 -9.225  -46.684 1.00 31.39  ? 141 PRO M CD  1 
ATOM   6476 N N   . ARG E 3 143 ? -27.231 -7.326  -43.797 1.00 33.94  ? 142 ARG M N   1 
ATOM   6477 C CA  . ARG E 3 143 ? -26.587 -7.411  -42.490 1.00 38.03  ? 142 ARG M CA  1 
ATOM   6478 C C   . ARG E 3 143 ? -27.588 -7.658  -41.368 1.00 38.93  ? 142 ARG M C   1 
ATOM   6479 O O   . ARG E 3 143 ? -27.270 -8.362  -40.402 1.00 37.34  ? 142 ARG M O   1 
ATOM   6480 C CB  . ARG E 3 143 ? -25.790 -6.129  -42.233 1.00 37.75  ? 142 ARG M CB  1 
ATOM   6481 C CG  . ARG E 3 143 ? -25.468 -5.841  -40.773 1.00 41.55  ? 142 ARG M CG  1 
ATOM   6482 C CD  . ARG E 3 143 ? -24.469 -6.817  -40.180 1.00 40.38  ? 142 ARG M CD  1 
ATOM   6483 N NE  . ARG E 3 143 ? -24.168 -6.472  -38.796 1.00 45.45  ? 142 ARG M NE  1 
ATOM   6484 C CZ  . ARG E 3 143 ? -24.848 -6.918  -37.749 1.00 43.60  ? 142 ARG M CZ  1 
ATOM   6485 N NH1 . ARG E 3 143 ? -25.865 -7.752  -37.890 1.00 38.76  ? 142 ARG M NH1 1 
ATOM   6486 N NH2 . ARG E 3 143 ? -24.500 -6.516  -36.529 1.00 40.18  ? 142 ARG M NH2 1 
ATOM   6487 N N   . GLU E 3 144 ? -28.798 -7.118  -41.484 1.00 38.10  ? 143 GLU M N   1 
ATOM   6488 C CA  . GLU E 3 144 ? -29.745 -7.160  -40.378 1.00 37.13  ? 143 GLU M CA  1 
ATOM   6489 C C   . GLU E 3 144 ? -30.177 -8.592  -40.090 1.00 43.49  ? 143 GLU M C   1 
ATOM   6490 O O   . GLU E 3 144 ? -30.535 -9.344  -41.001 1.00 36.75  ? 143 GLU M O   1 
ATOM   6491 C CB  . GLU E 3 144 ? -30.963 -6.294  -40.693 1.00 37.95  ? 143 GLU M CB  1 
ATOM   6492 C CG  . GLU E 3 144 ? -30.673 -4.800  -40.724 1.00 42.89  ? 143 GLU M CG  1 
ATOM   6493 C CD  . GLU E 3 144 ? -30.004 -4.352  -42.009 1.00 40.36  ? 143 GLU M CD  1 
ATOM   6494 O OE1 . GLU E 3 144 ? -29.848 -5.184  -42.928 1.00 41.64  ? 143 GLU M OE1 1 
ATOM   6495 O OE2 . GLU E 3 144 ? -29.629 -3.164  -42.099 1.00 47.47  ? 143 GLU M OE2 1 
ATOM   6496 N N   . ALA E 3 145 ? -30.139 -8.963  -38.814 1.00 40.16  ? 144 ALA M N   1 
ATOM   6497 C CA  . ALA E 3 145 ? -30.589 -10.269 -38.355 1.00 42.66  ? 144 ALA M CA  1 
ATOM   6498 C C   . ALA E 3 145 ? -30.928 -10.150 -36.875 1.00 46.89  ? 144 ALA M C   1 
ATOM   6499 O O   . ALA E 3 145 ? -30.730 -9.100  -36.257 1.00 46.07  ? 144 ALA M O   1 
ATOM   6500 C CB  . ALA E 3 145 ? -29.528 -11.345 -38.610 1.00 37.29  ? 144 ALA M CB  1 
ATOM   6501 N N   . LYS E 3 146 ? -31.443 -11.236 -36.305 1.00 41.22  ? 145 LYS M N   1 
ATOM   6502 C CA  . LYS E 3 146 ? -31.694 -11.273 -34.870 1.00 39.64  ? 145 LYS M CA  1 
ATOM   6503 C C   . LYS E 3 146 ? -31.368 -12.654 -34.328 1.00 39.66  ? 145 LYS M C   1 
ATOM   6504 O O   . LYS E 3 146 ? -31.819 -13.665 -34.875 1.00 42.42  ? 145 LYS M O   1 
ATOM   6505 C CB  . LYS E 3 146 ? -33.143 -10.898 -34.540 1.00 42.96  ? 145 LYS M CB  1 
ATOM   6506 C CG  . LYS E 3 146 ? -33.455 -10.876 -33.050 1.00 44.24  ? 145 LYS M CG  1 
ATOM   6507 C CD  . LYS E 3 146 ? -34.678 -10.021 -32.749 1.00 49.66  ? 145 LYS M CD  1 
ATOM   6508 C CE  . LYS E 3 146 ? -35.028 -10.041 -31.267 1.00 58.95  ? 145 LYS M CE  1 
ATOM   6509 N NZ  . LYS E 3 146 ? -33.928 -9.515  -30.416 1.00 57.99  ? 145 LYS M NZ  1 
ATOM   6510 N N   . VAL E 3 147 ? -30.591 -12.681 -33.247 1.00 37.02  ? 146 VAL M N   1 
ATOM   6511 C CA  . VAL E 3 147 ? -30.193 -13.905 -32.564 1.00 35.16  ? 146 VAL M CA  1 
ATOM   6512 C C   . VAL E 3 147 ? -30.810 -13.877 -31.174 1.00 33.46  ? 146 VAL M C   1 
ATOM   6513 O O   . VAL E 3 147 ? -30.596 -12.927 -30.410 1.00 38.11  ? 146 VAL M O   1 
ATOM   6514 C CB  . VAL E 3 147 ? -28.665 -14.040 -32.484 1.00 33.06  ? 146 VAL M CB  1 
ATOM   6515 C CG1 . VAL E 3 147 ? -28.278 -15.326 -31.770 1.00 30.97  ? 146 VAL M CG1 1 
ATOM   6516 C CG2 . VAL E 3 147 ? -28.052 -13.985 -33.872 1.00 38.54  ? 146 VAL M CG2 1 
ATOM   6517 N N   . GLN E 3 148 ? -31.577 -14.912 -30.847 1.00 33.16  ? 147 GLN M N   1 
ATOM   6518 C CA  . GLN E 3 148 ? -32.236 -15.034 -29.554 1.00 40.34  ? 147 GLN M CA  1 
ATOM   6519 C C   . GLN E 3 148 ? -31.765 -16.322 -28.896 1.00 34.27  ? 147 GLN M C   1 
ATOM   6520 O O   . GLN E 3 148 ? -31.932 -17.407 -29.462 1.00 32.82  ? 147 GLN M O   1 
ATOM   6521 C CB  . GLN E 3 148 ? -33.757 -15.040 -29.719 1.00 37.80  ? 147 GLN M CB  1 
ATOM   6522 C CG  . GLN E 3 148 ? -34.532 -14.725 -28.455 1.00 48.94  ? 147 GLN M CG  1 
ATOM   6523 C CD  . GLN E 3 148 ? -34.995 -13.284 -28.408 1.00 56.80  ? 147 GLN M CD  1 
ATOM   6524 O OE1 . GLN E 3 148 ? -35.832 -12.864 -29.205 1.00 58.20  ? 147 GLN M OE1 1 
ATOM   6525 N NE2 . GLN E 3 148 ? -34.449 -12.516 -27.473 1.00 57.80  ? 147 GLN M NE2 1 
ATOM   6526 N N   . TRP E 3 149 ? -31.177 -16.208 -27.712 1.00 34.06  ? 148 TRP M N   1 
ATOM   6527 C CA  . TRP E 3 149 ? -30.799 -17.382 -26.942 1.00 36.71  ? 148 TRP M CA  1 
ATOM   6528 C C   . TRP E 3 149 ? -31.994 -17.862 -26.131 1.00 33.08  ? 148 TRP M C   1 
ATOM   6529 O O   . TRP E 3 149 ? -32.698 -17.064 -25.505 1.00 30.65  ? 148 TRP M O   1 
ATOM   6530 C CB  . TRP E 3 149 ? -29.621 -17.075 -26.015 1.00 37.42  ? 148 TRP M CB  1 
ATOM   6531 C CG  . TRP E 3 149 ? -28.303 -16.998 -26.722 1.00 33.88  ? 148 TRP M CG  1 
ATOM   6532 C CD1 . TRP E 3 149 ? -27.632 -15.866 -27.083 1.00 31.86  ? 148 TRP M CD1 1 
ATOM   6533 C CD2 . TRP E 3 149 ? -27.496 -18.099 -27.158 1.00 31.93  ? 148 TRP M CD2 1 
ATOM   6534 N NE1 . TRP E 3 149 ? -26.457 -16.194 -27.714 1.00 31.96  ? 148 TRP M NE1 1 
ATOM   6535 C CE2 . TRP E 3 149 ? -26.350 -17.559 -27.772 1.00 32.36  ? 148 TRP M CE2 1 
ATOM   6536 C CE3 . TRP E 3 149 ? -27.631 -19.489 -27.085 1.00 28.69  ? 148 TRP M CE3 1 
ATOM   6537 C CZ2 . TRP E 3 149 ? -25.345 -18.360 -28.311 1.00 32.43  ? 148 TRP M CZ2 1 
ATOM   6538 C CZ3 . TRP E 3 149 ? -26.633 -20.282 -27.622 1.00 31.65  ? 148 TRP M CZ3 1 
ATOM   6539 C CH2 . TRP E 3 149 ? -25.505 -19.716 -28.226 1.00 33.43  ? 148 TRP M CH2 1 
ATOM   6540 N N   . LYS E 3 150 ? -32.223 -19.173 -26.150 1.00 36.20  ? 149 LYS M N   1 
ATOM   6541 C CA  . LYS E 3 150 ? -33.310 -19.786 -25.402 1.00 37.56  ? 149 LYS M CA  1 
ATOM   6542 C C   . LYS E 3 150 ? -32.781 -20.998 -24.652 1.00 38.49  ? 149 LYS M C   1 
ATOM   6543 O O   . LYS E 3 150 ? -32.208 -21.911 -25.256 1.00 33.98  ? 149 LYS M O   1 
ATOM   6544 C CB  . LYS E 3 150 ? -34.466 -20.180 -26.327 1.00 37.18  ? 149 LYS M CB  1 
ATOM   6545 C CG  . LYS E 3 150 ? -35.296 -18.993 -26.795 1.00 40.09  ? 149 LYS M CG  1 
ATOM   6546 C CD  . LYS E 3 150 ? -36.363 -19.406 -27.796 1.00 46.62  ? 149 LYS M CD  1 
ATOM   6547 C CE  . LYS E 3 150 ? -37.279 -18.239 -28.134 1.00 57.72  ? 149 LYS M CE  1 
ATOM   6548 N NZ  . LYS E 3 150 ? -38.218 -18.566 -29.241 1.00 55.86  ? 149 LYS M NZ  1 
ATOM   6549 N N   . VAL E 3 151 ? -32.983 -21.010 -23.340 1.00 38.32  ? 150 VAL M N   1 
ATOM   6550 C CA  . VAL E 3 151 ? -32.564 -22.113 -22.488 1.00 38.38  ? 150 VAL M CA  1 
ATOM   6551 C C   . VAL E 3 151 ? -33.824 -22.733 -21.904 1.00 41.64  ? 150 VAL M C   1 
ATOM   6552 O O   . VAL E 3 151 ? -34.486 -22.122 -21.054 1.00 39.18  ? 150 VAL M O   1 
ATOM   6553 C CB  . VAL E 3 151 ? -31.608 -21.650 -21.383 1.00 36.47  ? 150 VAL M CB  1 
ATOM   6554 C CG1 . VAL E 3 151 ? -31.185 -22.824 -20.538 1.00 36.96  ? 150 VAL M CG1 1 
ATOM   6555 C CG2 . VAL E 3 151 ? -30.394 -20.963 -21.987 1.00 36.01  ? 150 VAL M CG2 1 
ATOM   6556 N N   . ASP E 3 152 ? -34.146 -23.950 -22.344 1.00 37.39  ? 151 ASP M N   1 
ATOM   6557 C CA  . ASP E 3 152 ? -35.411 -24.606 -22.013 1.00 40.38  ? 151 ASP M CA  1 
ATOM   6558 C C   . ASP E 3 152 ? -36.591 -23.676 -22.288 1.00 43.38  ? 151 ASP M C   1 
ATOM   6559 O O   . ASP E 3 152 ? -37.480 -23.487 -21.454 1.00 43.90  ? 151 ASP M O   1 
ATOM   6560 C CB  . ASP E 3 152 ? -35.415 -25.098 -20.565 1.00 35.32  ? 151 ASP M CB  1 
ATOM   6561 C CG  . ASP E 3 152 ? -34.491 -26.282 -20.352 1.00 40.67  ? 151 ASP M CG  1 
ATOM   6562 O OD1 . ASP E 3 152 ? -34.270 -27.043 -21.317 1.00 44.84  ? 151 ASP M OD1 1 
ATOM   6563 O OD2 . ASP E 3 152 ? -33.990 -26.453 -19.222 1.00 38.53  ? 151 ASP M OD2 1 
ATOM   6564 N N   . ASN E 3 153 ? -36.574 -23.075 -23.478 1.00 42.39  ? 152 ASN M N   1 
ATOM   6565 C CA  . ASN E 3 153 ? -37.588 -22.157 -23.992 1.00 49.88  ? 152 ASN M CA  1 
ATOM   6566 C C   . ASN E 3 153 ? -37.644 -20.834 -23.240 1.00 42.58  ? 152 ASN M C   1 
ATOM   6567 O O   . ASN E 3 153 ? -38.562 -20.039 -23.477 1.00 49.20  ? 152 ASN M O   1 
ATOM   6568 C CB  . ASN E 3 153 ? -38.983 -22.794 -24.007 1.00 51.18  ? 152 ASN M CB  1 
ATOM   6569 C CG  . ASN E 3 153 ? -39.302 -23.459 -25.330 1.00 59.09  ? 152 ASN M CG  1 
ATOM   6570 O OD1 . ASN E 3 153 ? -39.184 -22.844 -26.389 1.00 65.89  ? 152 ASN M OD1 1 
ATOM   6571 N ND2 . ASN E 3 153 ? -39.699 -24.725 -25.278 1.00 62.22  ? 152 ASN M ND2 1 
ATOM   6572 N N   . ALA E 3 154 ? -36.695 -20.564 -22.350 1.00 41.62  ? 153 ALA M N   1 
ATOM   6573 C CA  . ALA E 3 154 ? -36.640 -19.293 -21.641 1.00 45.91  ? 153 ALA M CA  1 
ATOM   6574 C C   . ALA E 3 154 ? -35.691 -18.353 -22.371 1.00 41.58  ? 153 ALA M C   1 
ATOM   6575 O O   . ALA E 3 154 ? -34.526 -18.692 -22.601 1.00 42.95  ? 153 ALA M O   1 
ATOM   6576 C CB  . ALA E 3 154 ? -36.188 -19.489 -20.193 1.00 39.31  ? 153 ALA M CB  1 
ATOM   6577 N N   . LEU E 3 155 ? -36.188 -17.171 -22.721 1.00 38.91  ? 154 LEU M N   1 
ATOM   6578 C CA  . LEU E 3 155 ? -35.390 -16.206 -23.467 1.00 41.62  ? 154 LEU M CA  1 
ATOM   6579 C C   . LEU E 3 155 ? -34.324 -15.584 -22.575 1.00 43.78  ? 154 LEU M C   1 
ATOM   6580 O O   . LEU E 3 155 ? -34.619 -15.079 -21.487 1.00 46.38  ? 154 LEU M O   1 
ATOM   6581 C CB  . LEU E 3 155 ? -36.281 -15.122 -24.076 1.00 45.67  ? 154 LEU M CB  1 
ATOM   6582 C CG  . LEU E 3 155 ? -37.284 -15.450 -25.194 1.00 54.29  ? 154 LEU M CG  1 
ATOM   6583 C CD1 . LEU E 3 155 ? -38.269 -16.578 -24.888 1.00 52.73  ? 154 LEU M CD1 1 
ATOM   6584 C CD2 . LEU E 3 155 ? -38.030 -14.173 -25.551 1.00 56.90  ? 154 LEU M CD2 1 
ATOM   6585 N N   . GLN E 3 156 ? -33.084 -15.609 -23.051 1.00 37.02  ? 155 GLN M N   1 
ATOM   6586 C CA  . GLN E 3 156 ? -31.954 -15.070 -22.313 1.00 40.56  ? 155 GLN M CA  1 
ATOM   6587 C C   . GLN E 3 156 ? -31.758 -13.595 -22.640 1.00 44.34  ? 155 GLN M C   1 
ATOM   6588 O O   . GLN E 3 156 ? -32.020 -13.144 -23.758 1.00 49.61  ? 155 GLN M O   1 
ATOM   6589 C CB  . GLN E 3 156 ? -30.680 -15.852 -22.639 1.00 36.70  ? 155 GLN M CB  1 
ATOM   6590 C CG  . GLN E 3 156 ? -30.791 -17.338 -22.344 1.00 36.09  ? 155 GLN M CG  1 
ATOM   6591 C CD  . GLN E 3 156 ? -31.143 -17.623 -20.898 1.00 41.95  ? 155 GLN M CD  1 
ATOM   6592 O OE1 . GLN E 3 156 ? -30.354 -17.355 -19.991 1.00 37.83  ? 155 GLN M OE1 1 
ATOM   6593 N NE2 . GLN E 3 156 ? -32.332 -18.167 -20.674 1.00 38.34  ? 155 GLN M NE2 1 
ATOM   6594 N N   . SER E 3 157 ? -31.288 -12.844 -21.646 1.00 44.44  ? 156 SER M N   1 
ATOM   6595 C CA  . SER E 3 157 ? -31.072 -11.414 -21.812 1.00 43.02  ? 156 SER M CA  1 
ATOM   6596 C C   . SER E 3 157 ? -29.954 -10.963 -20.886 1.00 49.53  ? 156 SER M C   1 
ATOM   6597 O O   . SER E 3 157 ? -29.940 -11.325 -19.706 1.00 51.84  ? 156 SER M O   1 
ATOM   6598 C CB  . SER E 3 157 ? -32.355 -10.626 -21.523 1.00 50.32  ? 156 SER M CB  1 
ATOM   6599 O OG  . SER E 3 157 ? -32.150 -9.237  -21.702 1.00 50.78  ? 156 SER M OG  1 
ATOM   6600 N N   . GLY E 3 158 ? -29.025 -10.179 -21.426 1.00 46.83  ? 157 GLY M N   1 
ATOM   6601 C CA  . GLY E 3 158 ? -27.956 -9.603  -20.638 1.00 38.03  ? 157 GLY M CA  1 
ATOM   6602 C C   . GLY E 3 158 ? -26.813 -10.533 -20.308 1.00 40.75  ? 157 GLY M C   1 
ATOM   6603 O O   . GLY E 3 158 ? -25.960 -10.172 -19.488 1.00 47.20  ? 157 GLY M O   1 
ATOM   6604 N N   . ASN E 3 159 ? -26.765 -11.723 -20.909 1.00 38.10  ? 158 ASN M N   1 
ATOM   6605 C CA  . ASN E 3 159 ? -25.704 -12.685 -20.636 1.00 36.17  ? 158 ASN M CA  1 
ATOM   6606 C C   . ASN E 3 159 ? -25.092 -13.231 -21.922 1.00 35.11  ? 158 ASN M C   1 
ATOM   6607 O O   . ASN E 3 159 ? -24.565 -14.347 -21.937 1.00 37.39  ? 158 ASN M O   1 
ATOM   6608 C CB  . ASN E 3 159 ? -26.221 -13.825 -19.757 1.00 37.89  ? 158 ASN M CB  1 
ATOM   6609 C CG  . ASN E 3 159 ? -27.432 -14.515 -20.350 1.00 43.35  ? 158 ASN M CG  1 
ATOM   6610 O OD1 . ASN E 3 159 ? -28.059 -14.004 -21.278 1.00 37.82  ? 158 ASN M OD1 1 
ATOM   6611 N ND2 . ASN E 3 159 ? -27.772 -15.680 -19.813 1.00 41.53  ? 158 ASN M ND2 1 
ATOM   6612 N N   . SER E 3 160 ? -25.147 -12.461 -23.009 1.00 31.58  ? 159 SER M N   1 
ATOM   6613 C CA  . SER E 3 160 ? -24.540 -12.864 -24.269 1.00 38.58  ? 159 SER M CA  1 
ATOM   6614 C C   . SER E 3 160 ? -23.806 -11.684 -24.892 1.00 37.39  ? 159 SER M C   1 
ATOM   6615 O O   . SER E 3 160 ? -24.146 -10.523 -24.650 1.00 35.99  ? 159 SER M O   1 
ATOM   6616 C CB  . SER E 3 160 ? -25.585 -13.406 -25.254 1.00 33.78  ? 159 SER M CB  1 
ATOM   6617 O OG  . SER E 3 160 ? -26.546 -12.416 -25.579 1.00 35.74  ? 159 SER M OG  1 
ATOM   6618 N N   . GLN E 3 161 ? -22.793 -11.998 -25.700 1.00 34.11  ? 160 GLN M N   1 
ATOM   6619 C CA  . GLN E 3 161 ? -22.049 -10.990 -26.448 1.00 34.02  ? 160 GLN M CA  1 
ATOM   6620 C C   . GLN E 3 161 ? -21.805 -11.475 -27.869 1.00 36.57  ? 160 GLN M C   1 
ATOM   6621 O O   . GLN E 3 161 ? -21.493 -12.647 -28.083 1.00 34.45  ? 160 GLN M O   1 
ATOM   6622 C CB  . GLN E 3 161 ? -20.706 -10.666 -25.780 1.00 34.77  ? 160 GLN M CB  1 
ATOM   6623 C CG  . GLN E 3 161 ? -20.811 -9.756  -24.569 1.00 34.94  ? 160 GLN M CG  1 
ATOM   6624 C CD  . GLN E 3 161 ? -19.453 -9.374  -24.015 1.00 38.59  ? 160 GLN M CD  1 
ATOM   6625 O OE1 . GLN E 3 161 ? -18.601 -10.231 -23.785 1.00 43.39  ? 160 GLN M OE1 1 
ATOM   6626 N NE2 . GLN E 3 161 ? -19.241 -8.080  -23.807 1.00 33.38  ? 160 GLN M NE2 1 
ATOM   6627 N N   . GLU E 3 162 ? -21.913 -10.569 -28.838 1.00 30.90  ? 161 GLU M N   1 
ATOM   6628 C CA  . GLU E 3 162 ? -21.773 -10.938 -30.240 1.00 34.04  ? 161 GLU M CA  1 
ATOM   6629 C C   . GLU E 3 162 ? -20.787 -10.019 -30.948 1.00 31.11  ? 161 GLU M C   1 
ATOM   6630 O O   . GLU E 3 162 ? -20.502 -8.905  -30.500 1.00 27.90  ? 161 GLU M O   1 
ATOM   6631 C CB  . GLU E 3 162 ? -23.123 -10.904 -30.969 1.00 33.68  ? 161 GLU M CB  1 
ATOM   6632 C CG  . GLU E 3 162 ? -23.623 -9.508  -31.287 1.00 38.30  ? 161 GLU M CG  1 
ATOM   6633 C CD  . GLU E 3 162 ? -24.971 -9.523  -31.974 1.00 43.05  ? 161 GLU M CD  1 
ATOM   6634 O OE1 . GLU E 3 162 ? -25.749 -10.471 -31.735 1.00 43.22  ? 161 GLU M OE1 1 
ATOM   6635 O OE2 . GLU E 3 162 ? -25.254 -8.590  -32.755 1.00 46.68  ? 161 GLU M OE2 1 
ATOM   6636 N N   . SER E 3 163 ? -20.266 -10.519 -32.069 1.00 30.18  ? 162 SER M N   1 
ATOM   6637 C CA  . SER E 3 163 ? -19.338 -9.774  -32.909 1.00 32.91  ? 162 SER M CA  1 
ATOM   6638 C C   . SER E 3 163 ? -19.570 -10.167 -34.363 1.00 35.85  ? 162 SER M C   1 
ATOM   6639 O O   . SER E 3 163 ? -19.944 -11.305 -34.661 1.00 30.94  ? 162 SER M O   1 
ATOM   6640 C CB  . SER E 3 163 ? -17.877 -10.018 -32.511 1.00 31.06  ? 162 SER M CB  1 
ATOM   6641 O OG  . SER E 3 163 ? -17.388 -11.226 -33.063 1.00 33.60  ? 162 SER M OG  1 
ATOM   6642 N N   . VAL E 3 164 ? -19.340 -9.216  -35.268 1.00 36.75  ? 163 VAL M N   1 
ATOM   6643 C CA  . VAL E 3 164 ? -19.642 -9.385  -36.686 1.00 33.70  ? 163 VAL M CA  1 
ATOM   6644 C C   . VAL E 3 164 ? -18.405 -9.048  -37.509 1.00 33.32  ? 163 VAL M C   1 
ATOM   6645 O O   . VAL E 3 164 ? -17.714 -8.062  -37.233 1.00 33.36  ? 163 VAL M O   1 
ATOM   6646 C CB  . VAL E 3 164 ? -20.834 -8.503  -37.121 1.00 35.03  ? 163 VAL M CB  1 
ATOM   6647 C CG1 . VAL E 3 164 ? -21.154 -8.712  -38.593 1.00 32.65  ? 163 VAL M CG1 1 
ATOM   6648 C CG2 . VAL E 3 164 ? -22.052 -8.789  -36.260 1.00 35.27  ? 163 VAL M CG2 1 
ATOM   6649 N N   . THR E 3 165 ? -18.127 -9.874  -38.517 1.00 27.07  ? 164 THR M N   1 
ATOM   6650 C CA  . THR E 3 165 ? -17.021 -9.609  -39.423 1.00 37.20  ? 164 THR M CA  1 
ATOM   6651 C C   . THR E 3 165 ? -17.365 -8.466  -40.374 1.00 35.90  ? 164 THR M C   1 
ATOM   6652 O O   . THR E 3 165 ? -18.526 -8.078  -40.534 1.00 34.92  ? 164 THR M O   1 
ATOM   6653 C CB  . THR E 3 165 ? -16.669 -10.856 -40.238 1.00 31.43  ? 164 THR M CB  1 
ATOM   6654 O OG1 . THR E 3 165 ? -17.788 -11.233 -41.050 1.00 30.24  ? 164 THR M OG1 1 
ATOM   6655 C CG2 . THR E 3 165 ? -16.299 -12.012 -39.323 1.00 36.95  ? 164 THR M CG2 1 
ATOM   6656 N N   . GLU E 3 166 ? -16.330 -7.925  -41.010 1.00 38.82  ? 165 GLU M N   1 
ATOM   6657 C CA  . GLU E 3 166 ? -16.537 -6.973  -42.088 1.00 36.54  ? 165 GLU M CA  1 
ATOM   6658 C C   . GLU E 3 166 ? -17.094 -7.688  -43.316 1.00 35.57  ? 165 GLU M C   1 
ATOM   6659 O O   . GLU E 3 166 ? -17.072 -8.919  -43.413 1.00 30.78  ? 165 GLU M O   1 
ATOM   6660 C CB  . GLU E 3 166 ? -15.227 -6.266  -42.441 1.00 35.33  ? 165 GLU M CB  1 
ATOM   6661 C CG  . GLU E 3 166 ? -14.660 -5.400  -41.327 1.00 32.90  ? 165 GLU M CG  1 
ATOM   6662 C CD  . GLU E 3 166 ? -15.543 -4.212  -40.998 1.00 48.94  ? 165 GLU M CD  1 
ATOM   6663 O OE1 . GLU E 3 166 ? -16.267 -3.741  -41.899 1.00 55.72  ? 165 GLU M OE1 1 
ATOM   6664 O OE2 . GLU E 3 166 ? -15.507 -3.750  -39.840 1.00 52.26  ? 165 GLU M OE2 1 
ATOM   6665 N N   . GLN E 3 167 ? -17.610 -6.900  -44.257 1.00 39.00  ? 166 GLN M N   1 
ATOM   6666 C CA  . GLN E 3 167 ? -18.143 -7.467  -45.489 1.00 36.87  ? 166 GLN M CA  1 
ATOM   6667 C C   . GLN E 3 167 ? -17.045 -8.210  -46.236 1.00 39.56  ? 166 GLN M C   1 
ATOM   6668 O O   . GLN E 3 167 ? -15.998 -7.633  -46.551 1.00 43.20  ? 166 GLN M O   1 
ATOM   6669 C CB  . GLN E 3 167 ? -18.740 -6.369  -46.366 1.00 35.97  ? 166 GLN M CB  1 
ATOM   6670 C CG  . GLN E 3 167 ? -19.676 -6.887  -47.448 1.00 41.11  ? 166 GLN M CG  1 
ATOM   6671 C CD  . GLN E 3 167 ? -20.444 -5.776  -48.135 1.00 44.91  ? 166 GLN M CD  1 
ATOM   6672 O OE1 . GLN E 3 167 ? -20.115 -4.599  -47.992 1.00 46.24  ? 166 GLN M OE1 1 
ATOM   6673 N NE2 . GLN E 3 167 ? -21.469 -6.147  -48.894 1.00 41.16  ? 166 GLN M NE2 1 
ATOM   6674 N N   . ASP E 3 168 ? -17.281 -9.493  -46.504 1.00 35.12  ? 167 ASP M N   1 
ATOM   6675 C CA  . ASP E 3 168 ? -16.258 -10.331 -47.114 1.00 40.55  ? 167 ASP M CA  1 
ATOM   6676 C C   . ASP E 3 168 ? -15.865 -9.786  -48.481 1.00 51.03  ? 167 ASP M C   1 
ATOM   6677 O O   . ASP E 3 168 ? -16.718 -9.396  -49.283 1.00 46.43  ? 167 ASP M O   1 
ATOM   6678 C CB  . ASP E 3 168 ? -16.763 -11.769 -47.240 1.00 39.01  ? 167 ASP M CB  1 
ATOM   6679 C CG  . ASP E 3 168 ? -15.692 -12.723 -47.733 1.00 43.79  ? 167 ASP M CG  1 
ATOM   6680 O OD1 . ASP E 3 168 ? -14.822 -13.114 -46.927 1.00 41.88  ? 167 ASP M OD1 1 
ATOM   6681 O OD2 . ASP E 3 168 ? -15.723 -13.085 -48.925 1.00 43.43  ? 167 ASP M OD2 1 
ATOM   6682 N N   . SER E 3 169 ? -14.557 -9.758  -48.741 1.00 54.11  ? 168 SER M N   1 
ATOM   6683 C CA  . SER E 3 169 ? -14.054 -9.189  -49.985 1.00 48.39  ? 168 SER M CA  1 
ATOM   6684 C C   . SER E 3 169 ? -14.393 -10.044 -51.200 1.00 48.48  ? 168 SER M C   1 
ATOM   6685 O O   . SER E 3 169 ? -14.283 -9.559  -52.331 1.00 55.50  ? 168 SER M O   1 
ATOM   6686 C CB  . SER E 3 169 ? -12.541 -8.988  -49.894 1.00 47.64  ? 168 SER M CB  1 
ATOM   6687 O OG  . SER E 3 169 ? -11.875 -10.217 -49.662 1.00 50.00  ? 168 SER M OG  1 
ATOM   6688 N N   . LYS E 3 170 ? -14.799 -11.300 -50.999 1.00 51.64  ? 169 LYS M N   1 
ATOM   6689 C CA  . LYS E 3 170 ? -15.075 -12.211 -52.106 1.00 51.89  ? 169 LYS M CA  1 
ATOM   6690 C C   . LYS E 3 170 ? -16.566 -12.331 -52.410 1.00 56.08  ? 169 LYS M C   1 
ATOM   6691 O O   . LYS E 3 170 ? -16.989 -12.079 -53.541 1.00 57.95  ? 169 LYS M O   1 
ATOM   6692 C CB  . LYS E 3 170 ? -14.481 -13.594 -51.806 1.00 54.16  ? 169 LYS M CB  1 
ATOM   6693 C CG  . LYS E 3 170 ? -12.980 -13.592 -51.568 1.00 58.56  ? 169 LYS M CG  1 
ATOM   6694 C CD  . LYS E 3 170 ? -12.287 -14.646 -52.416 1.00 64.09  ? 169 LYS M CD  1 
ATOM   6695 C CE  . LYS E 3 170 ? -11.071 -15.218 -51.705 1.00 68.20  ? 169 LYS M CE  1 
ATOM   6696 N NZ  . LYS E 3 170 ? -10.162 -14.156 -51.195 1.00 70.90  ? 169 LYS M NZ  1 
ATOM   6697 N N   . ASP E 3 171 ? -17.378 -12.707 -51.420 1.00 43.28  ? 170 ASP M N   1 
ATOM   6698 C CA  . ASP E 3 171 ? -18.797 -12.953 -51.647 1.00 39.21  ? 170 ASP M CA  1 
ATOM   6699 C C   . ASP E 3 171 ? -19.708 -11.879 -51.066 1.00 36.95  ? 170 ASP M C   1 
ATOM   6700 O O   . ASP E 3 171 ? -20.931 -12.000 -51.187 1.00 45.04  ? 170 ASP M O   1 
ATOM   6701 C CB  . ASP E 3 171 ? -19.196 -14.332 -51.096 1.00 46.55  ? 170 ASP M CB  1 
ATOM   6702 C CG  . ASP E 3 171 ? -19.002 -14.459 -49.591 1.00 41.09  ? 170 ASP M CG  1 
ATOM   6703 O OD1 . ASP E 3 171 ? -18.887 -13.433 -48.890 1.00 40.57  ? 170 ASP M OD1 1 
ATOM   6704 O OD2 . ASP E 3 171 ? -18.971 -15.608 -49.101 1.00 43.08  ? 170 ASP M OD2 1 
ATOM   6705 N N   . SER E 3 172 ? -19.150 -10.849 -50.427 1.00 39.56  ? 171 SER M N   1 
ATOM   6706 C CA  . SER E 3 172 ? -19.887 -9.694  -49.917 1.00 39.14  ? 171 SER M CA  1 
ATOM   6707 C C   . SER E 3 172 ? -20.869 -10.045 -48.802 1.00 42.90  ? 171 SER M C   1 
ATOM   6708 O O   . SER E 3 172 ? -21.823 -9.297  -48.565 1.00 40.85  ? 171 SER M O   1 
ATOM   6709 C CB  . SER E 3 172 ? -20.628 -8.963  -51.044 1.00 41.38  ? 171 SER M CB  1 
ATOM   6710 O OG  . SER E 3 172 ? -19.725 -8.336  -51.937 1.00 49.59  ? 171 SER M OG  1 
ATOM   6711 N N   . THR E 3 173 ? -20.669 -11.161 -48.108 1.00 38.47  ? 172 THR M N   1 
ATOM   6712 C CA  . THR E 3 173 ? -21.545 -11.555 -47.014 1.00 41.30  ? 172 THR M CA  1 
ATOM   6713 C C   . THR E 3 173 ? -20.972 -11.121 -45.667 1.00 37.27  ? 172 THR M C   1 
ATOM   6714 O O   . THR E 3 173 ? -19.819 -10.699 -45.552 1.00 33.54  ? 172 THR M O   1 
ATOM   6715 C CB  . THR E 3 173 ? -21.774 -13.070 -47.021 1.00 36.15  ? 172 THR M CB  1 
ATOM   6716 O OG1 . THR E 3 173 ? -20.538 -13.744 -46.751 1.00 36.09  ? 172 THR M OG1 1 
ATOM   6717 C CG2 . THR E 3 173 ? -22.313 -13.523 -48.370 1.00 34.79  ? 172 THR M CG2 1 
ATOM   6718 N N   . TYR E 3 174 ? -21.808 -11.230 -44.639 1.00 34.54  ? 173 TYR M N   1 
ATOM   6719 C CA  . TYR E 3 174 ? -21.416 -11.015 -43.255 1.00 31.27  ? 173 TYR M CA  1 
ATOM   6720 C C   . TYR E 3 174 ? -21.466 -12.328 -42.482 1.00 35.29  ? 173 TYR M C   1 
ATOM   6721 O O   . TYR E 3 174 ? -22.130 -13.288 -42.883 1.00 34.39  ? 173 TYR M O   1 
ATOM   6722 C CB  . TYR E 3 174 ? -22.321 -9.980  -42.574 1.00 31.27  ? 173 TYR M CB  1 
ATOM   6723 C CG  . TYR E 3 174 ? -22.167 -8.566  -43.089 1.00 36.33  ? 173 TYR M CG  1 
ATOM   6724 C CD1 . TYR E 3 174 ? -21.211 -7.713  -42.554 1.00 39.41  ? 173 TYR M CD1 1 
ATOM   6725 C CD2 . TYR E 3 174 ? -22.986 -8.079  -44.099 1.00 39.03  ? 173 TYR M CD2 1 
ATOM   6726 C CE1 . TYR E 3 174 ? -21.068 -6.417  -43.014 1.00 40.40  ? 173 TYR M CE1 1 
ATOM   6727 C CE2 . TYR E 3 174 ? -22.850 -6.784  -44.567 1.00 39.26  ? 173 TYR M CE2 1 
ATOM   6728 C CZ  . TYR E 3 174 ? -21.890 -5.958  -44.022 1.00 40.79  ? 173 TYR M CZ  1 
ATOM   6729 O OH  . TYR E 3 174 ? -21.751 -4.669  -44.484 1.00 42.27  ? 173 TYR M OH  1 
ATOM   6730 N N   . SER E 3 175 ? -20.747 -12.358 -41.362 1.00 31.87  ? 174 SER M N   1 
ATOM   6731 C CA  . SER E 3 175 ? -20.807 -13.468 -40.423 1.00 31.04  ? 174 SER M CA  1 
ATOM   6732 C C   . SER E 3 175 ? -20.911 -12.917 -39.009 1.00 32.05  ? 174 SER M C   1 
ATOM   6733 O O   . SER E 3 175 ? -20.348 -11.865 -38.695 1.00 35.53  ? 174 SER M O   1 
ATOM   6734 C CB  . SER E 3 175 ? -19.584 -14.388 -40.546 1.00 33.54  ? 174 SER M CB  1 
ATOM   6735 O OG  . SER E 3 175 ? -19.647 -15.165 -41.729 1.00 34.24  ? 174 SER M OG  1 
ATOM   6736 N N   . LEU E 3 176 ? -21.641 -13.634 -38.158 1.00 28.54  ? 175 LEU M N   1 
ATOM   6737 C CA  . LEU E 3 176 ? -21.896 -13.201 -36.792 1.00 32.38  ? 175 LEU M CA  1 
ATOM   6738 C C   . LEU E 3 176 ? -21.609 -14.348 -35.837 1.00 29.98  ? 175 LEU M C   1 
ATOM   6739 O O   . LEU E 3 176 ? -21.942 -15.503 -36.118 1.00 28.39  ? 175 LEU M O   1 
ATOM   6740 C CB  . LEU E 3 176 ? -23.349 -12.722 -36.619 1.00 32.65  ? 175 LEU M CB  1 
ATOM   6741 C CG  . LEU E 3 176 ? -23.743 -12.024 -35.309 1.00 33.82  ? 175 LEU M CG  1 
ATOM   6742 C CD1 . LEU E 3 176 ? -24.835 -10.999 -35.570 1.00 33.79  ? 175 LEU M CD1 1 
ATOM   6743 C CD2 . LEU E 3 176 ? -24.200 -13.017 -34.245 1.00 35.57  ? 175 LEU M CD2 1 
ATOM   6744 N N   . SER E 3 177 ? -20.978 -14.028 -34.712 1.00 29.95  ? 176 SER M N   1 
ATOM   6745 C CA  . SER E 3 177 ? -20.692 -15.001 -33.669 1.00 32.06  ? 176 SER M CA  1 
ATOM   6746 C C   . SER E 3 177 ? -21.257 -14.480 -32.357 1.00 36.02  ? 176 SER M C   1 
ATOM   6747 O O   . SER E 3 177 ? -20.945 -13.356 -31.948 1.00 34.21  ? 176 SER M O   1 
ATOM   6748 C CB  . SER E 3 177 ? -19.187 -15.255 -33.547 1.00 35.77  ? 176 SER M CB  1 
ATOM   6749 O OG  . SER E 3 177 ? -18.908 -16.175 -32.507 1.00 35.63  ? 176 SER M OG  1 
ATOM   6750 N N   . SER E 3 178 ? -22.086 -15.292 -31.703 1.00 34.61  ? 177 SER M N   1 
ATOM   6751 C CA  . SER E 3 178 ? -22.697 -14.934 -30.430 1.00 35.25  ? 177 SER M CA  1 
ATOM   6752 C C   . SER E 3 178 ? -22.302 -15.954 -29.372 1.00 35.88  ? 177 SER M C   1 
ATOM   6753 O O   . SER E 3 178 ? -22.392 -17.162 -29.603 1.00 34.79  ? 177 SER M O   1 
ATOM   6754 C CB  . SER E 3 178 ? -24.222 -14.859 -30.556 1.00 31.15  ? 177 SER M CB  1 
ATOM   6755 O OG  . SER E 3 178 ? -24.821 -14.502 -29.323 1.00 39.16  ? 177 SER M OG  1 
ATOM   6756 N N   . THR E 3 179 ? -21.865 -15.468 -28.214 1.00 34.34  ? 178 THR M N   1 
ATOM   6757 C CA  . THR E 3 179 ? -21.442 -16.315 -27.107 1.00 36.19  ? 178 THR M CA  1 
ATOM   6758 C C   . THR E 3 179 ? -22.346 -16.058 -25.912 1.00 36.04  ? 178 THR M C   1 
ATOM   6759 O O   . THR E 3 179 ? -22.460 -14.916 -25.447 1.00 35.58  ? 178 THR M O   1 
ATOM   6760 C CB  . THR E 3 179 ? -19.979 -16.061 -26.737 1.00 34.07  ? 178 THR M CB  1 
ATOM   6761 O OG1 . THR E 3 179 ? -19.144 -16.355 -27.862 1.00 38.68  ? 178 THR M OG1 1 
ATOM   6762 C CG2 . THR E 3 179 ? -19.566 -16.938 -25.567 1.00 34.29  ? 178 THR M CG2 1 
ATOM   6763 N N   . LEU E 3 180 ? -23.005 -17.117 -25.444 1.00 39.04  ? 179 LEU M N   1 
ATOM   6764 C CA  . LEU E 3 180 ? -23.762 -17.113 -24.200 1.00 39.89  ? 179 LEU M CA  1 
ATOM   6765 C C   . LEU E 3 180 ? -22.891 -17.715 -23.105 1.00 35.28  ? 179 LEU M C   1 
ATOM   6766 O O   . LEU E 3 180 ? -22.430 -18.855 -23.233 1.00 39.83  ? 179 LEU M O   1 
ATOM   6767 C CB  . LEU E 3 180 ? -25.060 -17.905 -24.352 1.00 34.67  ? 179 LEU M CB  1 
ATOM   6768 C CG  . LEU E 3 180 ? -25.924 -18.036 -23.099 1.00 40.90  ? 179 LEU M CG  1 
ATOM   6769 C CD1 . LEU E 3 180 ? -26.696 -16.752 -22.846 1.00 39.21  ? 179 LEU M CD1 1 
ATOM   6770 C CD2 . LEU E 3 180 ? -26.868 -19.223 -23.220 1.00 39.39  ? 179 LEU M CD2 1 
ATOM   6771 N N   . THR E 3 181 ? -22.668 -16.958 -22.035 1.00 34.01  ? 180 THR M N   1 
ATOM   6772 C CA  . THR E 3 181 ? -21.774 -17.366 -20.961 1.00 42.42  ? 180 THR M CA  1 
ATOM   6773 C C   . THR E 3 181 ? -22.565 -17.561 -19.676 1.00 41.28  ? 180 THR M C   1 
ATOM   6774 O O   . THR E 3 181 ? -23.312 -16.669 -19.260 1.00 41.58  ? 180 THR M O   1 
ATOM   6775 C CB  . THR E 3 181 ? -20.668 -16.329 -20.749 1.00 41.73  ? 180 THR M CB  1 
ATOM   6776 O OG1 . THR E 3 181 ? -19.952 -16.139 -21.977 1.00 50.33  ? 180 THR M OG1 1 
ATOM   6777 C CG2 . THR E 3 181 ? -19.699 -16.793 -19.673 1.00 41.27  ? 180 THR M CG2 1 
ATOM   6778 N N   . LEU E 3 182 ? -22.396 -18.725 -19.052 1.00 44.07  ? 181 LEU M N   1 
ATOM   6779 C CA  . LEU E 3 182 ? -23.043 -19.044 -17.787 1.00 46.09  ? 181 LEU M CA  1 
ATOM   6780 C C   . LEU E 3 182 ? -22.033 -19.682 -16.843 1.00 42.45  ? 181 LEU M C   1 
ATOM   6781 O O   . LEU E 3 182 ? -20.970 -20.148 -17.258 1.00 42.76  ? 181 LEU M O   1 
ATOM   6782 C CB  . LEU E 3 182 ? -24.242 -19.990 -17.968 1.00 46.40  ? 181 LEU M CB  1 
ATOM   6783 C CG  . LEU E 3 182 ? -25.332 -19.635 -18.981 1.00 45.17  ? 181 LEU M CG  1 
ATOM   6784 C CD1 . LEU E 3 182 ? -26.322 -20.780 -19.107 1.00 50.35  ? 181 LEU M CD1 1 
ATOM   6785 C CD2 . LEU E 3 182 ? -26.047 -18.364 -18.561 1.00 46.08  ? 181 LEU M CD2 1 
ATOM   6786 N N   . SER E 3 183 ? -22.361 -19.666 -15.555 1.00 43.65  ? 182 SER M N   1 
ATOM   6787 C CA  . SER E 3 183 ? -21.620 -20.477 -14.601 1.00 51.47  ? 182 SER M CA  1 
ATOM   6788 C C   . SER E 3 183 ? -21.907 -21.954 -14.844 1.00 51.06  ? 182 SER M C   1 
ATOM   6789 O O   . SER E 3 183 ? -22.952 -22.324 -15.386 1.00 47.10  ? 182 SER M O   1 
ATOM   6790 C CB  . SER E 3 183 ? -21.990 -20.093 -13.169 1.00 54.73  ? 182 SER M CB  1 
ATOM   6791 O OG  . SER E 3 183 ? -23.368 -20.309 -12.923 1.00 57.01  ? 182 SER M OG  1 
ATOM   6792 N N   . LYS E 3 184 ? -20.957 -22.806 -14.447 1.00 50.07  ? 183 LYS M N   1 
ATOM   6793 C CA  . LYS E 3 184 ? -21.142 -24.245 -14.611 1.00 51.33  ? 183 LYS M CA  1 
ATOM   6794 C C   . LYS E 3 184 ? -22.381 -24.726 -13.868 1.00 55.25  ? 183 LYS M C   1 
ATOM   6795 O O   . LYS E 3 184 ? -23.116 -25.595 -14.358 1.00 54.48  ? 183 LYS M O   1 
ATOM   6796 C CB  . LYS E 3 184 ? -19.901 -24.994 -14.124 1.00 50.36  ? 183 LYS M CB  1 
ATOM   6797 C CG  . LYS E 3 184 ? -19.933 -26.490 -14.399 1.00 61.90  ? 183 LYS M CG  1 
ATOM   6798 C CD  . LYS E 3 184 ? -18.780 -27.206 -13.714 1.00 61.25  ? 183 LYS M CD  1 
ATOM   6799 C CE  . LYS E 3 184 ? -19.275 -28.241 -12.716 1.00 63.44  ? 183 LYS M CE  1 
ATOM   6800 N NZ  . LYS E 3 184 ? -20.010 -27.618 -11.583 1.00 62.33  ? 183 LYS M NZ  1 
ATOM   6801 N N   . ALA E 3 185 ? -22.638 -24.159 -12.689 1.00 54.37  ? 184 ALA M N   1 
ATOM   6802 C CA  . ALA E 3 185 ? -23.819 -24.537 -11.923 1.00 56.64  ? 184 ALA M CA  1 
ATOM   6803 C C   . ALA E 3 185 ? -25.097 -24.138 -12.650 1.00 50.72  ? 184 ALA M C   1 
ATOM   6804 O O   . ALA E 3 185 ? -26.008 -24.958 -12.815 1.00 52.77  ? 184 ALA M O   1 
ATOM   6805 C CB  . ALA E 3 185 ? -23.767 -23.908 -10.530 1.00 56.54  ? 184 ALA M CB  1 
ATOM   6806 N N   . ASP E 3 186 ? -25.191 -22.877 -13.084 1.00 50.45  ? 185 ASP M N   1 
ATOM   6807 C CA  . ASP E 3 186 ? -26.363 -22.461 -13.847 1.00 55.16  ? 185 ASP M CA  1 
ATOM   6808 C C   . ASP E 3 186 ? -26.488 -23.245 -15.146 1.00 45.59  ? 185 ASP M C   1 
ATOM   6809 O O   . ASP E 3 186 ? -27.605 -23.478 -15.627 1.00 48.42  ? 185 ASP M O   1 
ATOM   6810 C CB  . ASP E 3 186 ? -26.315 -20.965 -14.159 1.00 59.08  ? 185 ASP M CB  1 
ATOM   6811 C CG  . ASP E 3 186 ? -26.876 -20.118 -13.039 1.00 65.46  ? 185 ASP M CG  1 
ATOM   6812 O OD1 . ASP E 3 186 ? -27.102 -20.665 -11.938 1.00 67.09  ? 185 ASP M OD1 1 
ATOM   6813 O OD2 . ASP E 3 186 ? -27.139 -18.917 -13.273 1.00 67.47  ? 185 ASP M OD2 1 
ATOM   6814 N N   . TYR E 3 187 ? -25.358 -23.650 -15.732 1.00 46.11  ? 186 TYR M N   1 
ATOM   6815 C CA  . TYR E 3 187 ? -25.401 -24.445 -16.954 1.00 47.64  ? 186 TYR M CA  1 
ATOM   6816 C C   . TYR E 3 187 ? -26.017 -25.815 -16.700 1.00 48.17  ? 186 TYR M C   1 
ATOM   6817 O O   . TYR E 3 187 ? -26.861 -26.276 -17.478 1.00 45.56  ? 186 TYR M O   1 
ATOM   6818 C CB  . TYR E 3 187 ? -23.994 -24.580 -17.537 1.00 39.62  ? 186 TYR M CB  1 
ATOM   6819 C CG  . TYR E 3 187 ? -23.908 -25.447 -18.777 1.00 46.06  ? 186 TYR M CG  1 
ATOM   6820 C CD1 . TYR E 3 187 ? -24.539 -25.073 -19.955 1.00 41.05  ? 186 TYR M CD1 1 
ATOM   6821 C CD2 . TYR E 3 187 ? -23.176 -26.627 -18.775 1.00 41.50  ? 186 TYR M CD2 1 
ATOM   6822 C CE1 . TYR E 3 187 ? -24.459 -25.859 -21.092 1.00 35.33  ? 186 TYR M CE1 1 
ATOM   6823 C CE2 . TYR E 3 187 ? -23.087 -27.417 -19.907 1.00 41.40  ? 186 TYR M CE2 1 
ATOM   6824 C CZ  . TYR E 3 187 ? -23.732 -27.030 -21.062 1.00 42.86  ? 186 TYR M CZ  1 
ATOM   6825 O OH  . TYR E 3 187 ? -23.648 -27.813 -22.191 1.00 37.09  ? 186 TYR M OH  1 
ATOM   6826 N N   . GLU E 3 188 ? -25.615 -26.476 -15.614 1.00 49.16  ? 187 GLU M N   1 
ATOM   6827 C CA  . GLU E 3 188 ? -26.131 -27.806 -15.310 1.00 49.93  ? 187 GLU M CA  1 
ATOM   6828 C C   . GLU E 3 188 ? -27.559 -27.788 -14.775 1.00 42.80  ? 187 GLU M C   1 
ATOM   6829 O O   . GLU E 3 188 ? -28.147 -28.860 -14.599 1.00 47.94  ? 187 GLU M O   1 
ATOM   6830 C CB  . GLU E 3 188 ? -25.199 -28.505 -14.318 1.00 48.07  ? 187 GLU M CB  1 
ATOM   6831 C CG  . GLU E 3 188 ? -23.878 -28.931 -14.943 1.00 52.50  ? 187 GLU M CG  1 
ATOM   6832 C CD  . GLU E 3 188 ? -22.829 -29.298 -13.916 1.00 65.15  ? 187 GLU M CD  1 
ATOM   6833 O OE1 . GLU E 3 188 ? -23.038 -29.007 -12.720 1.00 65.14  ? 187 GLU M OE1 1 
ATOM   6834 O OE2 . GLU E 3 188 ? -21.793 -29.875 -14.306 1.00 69.89  ? 187 GLU M OE2 1 
ATOM   6835 N N   . LYS E 3 189 ? -28.126 -26.612 -14.510 1.00 43.03  ? 188 LYS M N   1 
ATOM   6836 C CA  . LYS E 3 189 ? -29.505 -26.505 -14.045 1.00 44.46  ? 188 LYS M CA  1 
ATOM   6837 C C   . LYS E 3 189 ? -30.530 -26.581 -15.169 1.00 45.30  ? 188 LYS M C   1 
ATOM   6838 O O   . LYS E 3 189 ? -31.729 -26.456 -14.896 1.00 42.00  ? 188 LYS M O   1 
ATOM   6839 C CB  . LYS E 3 189 ? -29.701 -25.196 -13.275 1.00 46.76  ? 188 LYS M CB  1 
ATOM   6840 C CG  . LYS E 3 189 ? -29.651 -25.341 -11.767 1.00 50.39  ? 188 LYS M CG  1 
ATOM   6841 C CD  . LYS E 3 189 ? -28.996 -24.135 -11.114 1.00 57.50  ? 188 LYS M CD  1 
ATOM   6842 C CE  . LYS E 3 189 ? -28.573 -24.452 -9.690  1.00 54.91  ? 188 LYS M CE  1 
ATOM   6843 N NZ  . LYS E 3 189 ? -27.195 -25.011 -9.633  1.00 52.21  ? 188 LYS M NZ  1 
ATOM   6844 N N   . HIS E 3 190 ? -30.102 -26.778 -16.414 1.00 47.68  ? 189 HIS M N   1 
ATOM   6845 C CA  . HIS E 3 190 ? -31.009 -26.768 -17.552 1.00 43.17  ? 189 HIS M CA  1 
ATOM   6846 C C   . HIS E 3 190 ? -30.597 -27.847 -18.543 1.00 37.71  ? 189 HIS M C   1 
ATOM   6847 O O   . HIS E 3 190 ? -29.529 -28.455 -18.427 1.00 39.86  ? 189 HIS M O   1 
ATOM   6848 C CB  . HIS E 3 190 ? -31.037 -25.396 -18.230 1.00 41.99  ? 189 HIS M CB  1 
ATOM   6849 C CG  . HIS E 3 190 ? -31.426 -24.277 -17.315 1.00 38.79  ? 189 HIS M CG  1 
ATOM   6850 N ND1 . HIS E 3 190 ? -30.499 -23.510 -16.641 1.00 43.68  ? 189 HIS M ND1 1 
ATOM   6851 C CD2 . HIS E 3 190 ? -32.640 -23.796 -16.960 1.00 39.34  ? 189 HIS M CD2 1 
ATOM   6852 C CE1 . HIS E 3 190 ? -31.126 -22.604 -15.913 1.00 39.05  ? 189 HIS M CE1 1 
ATOM   6853 N NE2 . HIS E 3 190 ? -32.426 -22.756 -16.088 1.00 43.75  ? 189 HIS M NE2 1 
ATOM   6854 N N   . LYS E 3 191 ? -31.462 -28.079 -19.532 1.00 39.25  ? 190 LYS M N   1 
ATOM   6855 C CA  . LYS E 3 191 ? -31.304 -29.196 -20.458 1.00 41.31  ? 190 LYS M CA  1 
ATOM   6856 C C   . LYS E 3 191 ? -31.097 -28.741 -21.897 1.00 37.12  ? 190 LYS M C   1 
ATOM   6857 O O   . LYS E 3 191 ? -30.074 -29.080 -22.502 1.00 39.96  ? 190 LYS M O   1 
ATOM   6858 C CB  . LYS E 3 191 ? -32.525 -30.121 -20.362 1.00 41.84  ? 190 LYS M CB  1 
ATOM   6859 C CG  . LYS E 3 191 ? -32.756 -30.700 -18.976 1.00 44.34  ? 190 LYS M CG  1 
ATOM   6860 C CD  . LYS E 3 191 ? -34.026 -31.534 -18.924 1.00 39.74  ? 190 LYS M CD  1 
ATOM   6861 C CE  . LYS E 3 191 ? -35.259 -30.675 -19.149 1.00 40.01  ? 190 LYS M CE  1 
ATOM   6862 N NZ  . LYS E 3 191 ? -36.516 -31.471 -19.066 1.00 49.40  ? 190 LYS M NZ  1 
ATOM   6863 N N   . VAL E 3 192 ? -32.031 -27.985 -22.466 1.00 35.23  ? 191 VAL M N   1 
ATOM   6864 C CA  . VAL E 3 192 ? -32.030 -27.660 -23.889 1.00 43.25  ? 191 VAL M CA  1 
ATOM   6865 C C   . VAL E 3 192 ? -31.475 -26.255 -24.076 1.00 37.62  ? 191 VAL M C   1 
ATOM   6866 O O   . VAL E 3 192 ? -32.005 -25.288 -23.517 1.00 36.61  ? 191 VAL M O   1 
ATOM   6867 C CB  . VAL E 3 192 ? -33.439 -27.769 -24.491 1.00 41.79  ? 191 VAL M CB  1 
ATOM   6868 C CG1 . VAL E 3 192 ? -33.434 -27.298 -25.940 1.00 40.20  ? 191 VAL M CG1 1 
ATOM   6869 C CG2 . VAL E 3 192 ? -33.955 -29.193 -24.389 1.00 42.68  ? 191 VAL M CG2 1 
ATOM   6870 N N   . TYR E 3 193 ? -30.409 -26.141 -24.864 1.00 32.21  ? 192 TYR M N   1 
ATOM   6871 C CA  . TYR E 3 193 ? -29.800 -24.859 -25.191 1.00 36.23  ? 192 TYR M CA  1 
ATOM   6872 C C   . TYR E 3 193 ? -29.946 -24.614 -26.684 1.00 34.23  ? 192 TYR M C   1 
ATOM   6873 O O   . TYR E 3 193 ? -29.533 -25.452 -27.493 1.00 34.93  ? 192 TYR M O   1 
ATOM   6874 C CB  . TYR E 3 193 ? -28.328 -24.830 -24.780 1.00 33.46  ? 192 TYR M CB  1 
ATOM   6875 C CG  . TYR E 3 193 ? -28.137 -24.791 -23.286 1.00 37.43  ? 192 TYR M CG  1 
ATOM   6876 C CD1 . TYR E 3 193 ? -28.182 -25.955 -22.532 1.00 36.33  ? 192 TYR M CD1 1 
ATOM   6877 C CD2 . TYR E 3 193 ? -27.927 -23.589 -22.626 1.00 34.89  ? 192 TYR M CD2 1 
ATOM   6878 C CE1 . TYR E 3 193 ? -28.016 -25.924 -21.165 1.00 39.09  ? 192 TYR M CE1 1 
ATOM   6879 C CE2 . TYR E 3 193 ? -27.758 -23.549 -21.259 1.00 38.07  ? 192 TYR M CE2 1 
ATOM   6880 C CZ  . TYR E 3 193 ? -27.806 -24.718 -20.534 1.00 42.26  ? 192 TYR M CZ  1 
ATOM   6881 O OH  . TYR E 3 193 ? -27.640 -24.680 -19.171 1.00 44.10  ? 192 TYR M OH  1 
ATOM   6882 N N   . ALA E 3 194 ? -30.528 -23.471 -27.049 1.00 32.70  ? 193 ALA M N   1 
ATOM   6883 C CA  . ALA E 3 194 ? -30.864 -23.194 -28.435 1.00 35.96  ? 193 ALA M CA  1 
ATOM   6884 C C   . ALA E 3 194 ? -30.546 -21.746 -28.770 1.00 33.06  ? 193 ALA M C   1 
ATOM   6885 O O   . ALA E 3 194 ? -30.657 -20.855 -27.924 1.00 30.28  ? 193 ALA M O   1 
ATOM   6886 C CB  . ALA E 3 194 ? -32.348 -23.466 -28.718 1.00 31.25  ? 193 ALA M CB  1 
ATOM   6887 N N   . CYS E 3 195 ? -30.150 -21.522 -30.020 1.00 35.05  ? 194 CYS M N   1 
ATOM   6888 C CA  . CYS E 3 195 ? -30.123 -20.185 -30.591 1.00 35.29  ? 194 CYS M CA  1 
ATOM   6889 C C   . CYS E 3 195 ? -31.078 -20.141 -31.775 1.00 33.82  ? 194 CYS M C   1 
ATOM   6890 O O   . CYS E 3 195 ? -31.055 -21.027 -32.640 1.00 30.94  ? 194 CYS M O   1 
ATOM   6891 C CB  . CYS E 3 195 ? -28.703 -19.751 -30.990 1.00 35.87  ? 194 CYS M CB  1 
ATOM   6892 S SG  . CYS E 3 195 ? -27.836 -20.683 -32.276 1.00 48.20  ? 194 CYS M SG  1 
ATOM   6893 N N   . GLU E 3 196 ? -31.928 -19.118 -31.786 1.00 32.24  ? 195 GLU M N   1 
ATOM   6894 C CA  . GLU E 3 196 ? -32.972 -18.928 -32.781 1.00 35.43  ? 195 GLU M CA  1 
ATOM   6895 C C   . GLU E 3 196 ? -32.652 -17.681 -33.590 1.00 36.44  ? 195 GLU M C   1 
ATOM   6896 O O   . GLU E 3 196 ? -32.449 -16.602 -33.023 1.00 34.05  ? 195 GLU M O   1 
ATOM   6897 C CB  . GLU E 3 196 ? -34.339 -18.796 -32.104 1.00 34.28  ? 195 GLU M CB  1 
ATOM   6898 C CG  . GLU E 3 196 ? -35.483 -18.408 -33.024 1.00 44.98  ? 195 GLU M CG  1 
ATOM   6899 C CD  . GLU E 3 196 ? -36.728 -18.013 -32.250 1.00 49.31  ? 195 GLU M CD  1 
ATOM   6900 O OE1 . GLU E 3 196 ? -37.247 -18.857 -31.490 1.00 58.47  ? 195 GLU M OE1 1 
ATOM   6901 O OE2 . GLU E 3 196 ? -37.179 -16.856 -32.391 1.00 57.96  ? 195 GLU M OE2 1 
ATOM   6902 N N   . VAL E 3 197 ? -32.614 -17.827 -34.909 1.00 36.66  ? 196 VAL M N   1 
ATOM   6903 C CA  . VAL E 3 197 ? -32.142 -16.785 -35.808 1.00 36.58  ? 196 VAL M CA  1 
ATOM   6904 C C   . VAL E 3 197 ? -33.284 -16.368 -36.720 1.00 32.51  ? 196 VAL M C   1 
ATOM   6905 O O   . VAL E 3 197 ? -33.977 -17.222 -37.288 1.00 35.40  ? 196 VAL M O   1 
ATOM   6906 C CB  . VAL E 3 197 ? -30.931 -17.261 -36.630 1.00 36.75  ? 196 VAL M CB  1 
ATOM   6907 C CG1 . VAL E 3 197 ? -30.558 -16.229 -37.681 1.00 26.58  ? 196 VAL M CG1 1 
ATOM   6908 C CG2 . VAL E 3 197 ? -29.751 -17.554 -35.713 1.00 28.25  ? 196 VAL M CG2 1 
ATOM   6909 N N   . THR E 3 198 ? -33.481 -15.057 -36.847 1.00 33.05  ? 197 THR M N   1 
ATOM   6910 C CA  . THR E 3 198 ? -34.414 -14.488 -37.808 1.00 42.37  ? 197 THR M CA  1 
ATOM   6911 C C   . THR E 3 198 ? -33.649 -13.603 -38.782 1.00 39.14  ? 197 THR M C   1 
ATOM   6912 O O   . THR E 3 198 ? -32.762 -12.841 -38.380 1.00 39.02  ? 197 THR M O   1 
ATOM   6913 C CB  . THR E 3 198 ? -35.525 -13.681 -37.126 1.00 38.84  ? 197 THR M CB  1 
ATOM   6914 O OG1 . THR E 3 198 ? -34.949 -12.645 -36.325 1.00 48.67  ? 197 THR M OG1 1 
ATOM   6915 C CG2 . THR E 3 198 ? -36.376 -14.579 -36.247 1.00 40.68  ? 197 THR M CG2 1 
ATOM   6916 N N   . HIS E 3 199 ? -34.014 -13.707 -40.059 1.00 37.54  ? 198 HIS M N   1 
ATOM   6917 C CA  . HIS E 3 199 ? -33.377 -12.975 -41.144 1.00 35.92  ? 198 HIS M CA  1 
ATOM   6918 C C   . HIS E 3 199 ? -34.386 -12.832 -42.274 1.00 36.48  ? 198 HIS M C   1 
ATOM   6919 O O   . HIS E 3 199 ? -35.292 -13.659 -42.417 1.00 34.62  ? 198 HIS M O   1 
ATOM   6920 C CB  . HIS E 3 199 ? -32.110 -13.697 -41.626 1.00 31.59  ? 198 HIS M CB  1 
ATOM   6921 C CG  . HIS E 3 199 ? -31.322 -12.935 -42.646 1.00 38.18  ? 198 HIS M CG  1 
ATOM   6922 N ND1 . HIS E 3 199 ? -31.505 -13.099 -44.002 1.00 33.72  ? 198 HIS M ND1 1 
ATOM   6923 C CD2 . HIS E 3 199 ? -30.338 -12.016 -42.507 1.00 39.07  ? 198 HIS M CD2 1 
ATOM   6924 C CE1 . HIS E 3 199 ? -30.674 -12.306 -44.655 1.00 34.99  ? 198 HIS M CE1 1 
ATOM   6925 N NE2 . HIS E 3 199 ? -29.955 -11.638 -43.771 1.00 30.45  ? 198 HIS M NE2 1 
ATOM   6926 N N   . GLN E 3 200 ? -34.235 -11.767 -43.071 1.00 34.34  ? 199 GLN M N   1 
ATOM   6927 C CA  . GLN E 3 200 ? -35.204 -11.505 -44.133 1.00 34.48  ? 199 GLN M CA  1 
ATOM   6928 C C   . GLN E 3 200 ? -35.214 -12.593 -45.198 1.00 29.33  ? 199 GLN M C   1 
ATOM   6929 O O   . GLN E 3 200 ? -36.225 -12.754 -45.890 1.00 28.89  ? 199 GLN M O   1 
ATOM   6930 C CB  . GLN E 3 200 ? -34.959 -10.129 -44.760 1.00 39.19  ? 199 GLN M CB  1 
ATOM   6931 C CG  . GLN E 3 200 ? -35.517 -8.988  -43.913 1.00 33.22  ? 199 GLN M CG  1 
ATOM   6932 C CD  . GLN E 3 200 ? -35.559 -7.657  -44.637 1.00 37.57  ? 199 GLN M CD  1 
ATOM   6933 O OE1 . GLN E 3 200 ? -34.870 -7.452  -45.635 1.00 39.89  ? 199 GLN M OE1 1 
ATOM   6934 N NE2 . GLN E 3 200 ? -36.382 -6.742  -44.134 1.00 35.86  ? 199 GLN M NE2 1 
ATOM   6935 N N   . GLY E 3 201 ? -34.130 -13.347 -45.336 1.00 35.20  ? 200 GLY M N   1 
ATOM   6936 C CA  . GLY E 3 201 ? -34.111 -14.485 -46.228 1.00 30.12  ? 200 GLY M CA  1 
ATOM   6937 C C   . GLY E 3 201 ? -34.733 -15.748 -45.678 1.00 30.88  ? 200 GLY M C   1 
ATOM   6938 O O   . GLY E 3 201 ? -34.730 -16.777 -46.359 1.00 34.39  ? 200 GLY M O   1 
ATOM   6939 N N   . LEU E 3 202 ? -35.263 -15.705 -44.459 1.00 33.76  ? 201 LEU M N   1 
ATOM   6940 C CA  . LEU E 3 202 ? -35.887 -16.857 -43.821 1.00 30.80  ? 201 LEU M CA  1 
ATOM   6941 C C   . LEU E 3 202 ? -37.385 -16.620 -43.686 1.00 29.08  ? 201 LEU M C   1 
ATOM   6942 O O   . LEU E 3 202 ? -37.808 -15.596 -43.139 1.00 29.66  ? 201 LEU M O   1 
ATOM   6943 C CB  . LEU E 3 202 ? -35.274 -17.117 -42.442 1.00 30.65  ? 201 LEU M CB  1 
ATOM   6944 C CG  . LEU E 3 202 ? -33.792 -17.489 -42.384 1.00 31.09  ? 201 LEU M CG  1 
ATOM   6945 C CD1 . LEU E 3 202 ? -33.300 -17.494 -40.944 1.00 31.56  ? 201 LEU M CD1 1 
ATOM   6946 C CD2 . LEU E 3 202 ? -33.553 -18.839 -43.041 1.00 27.51  ? 201 LEU M CD2 1 
ATOM   6947 N N   . SER E 3 203 ? -38.184 -17.568 -44.185 1.00 32.35  ? 202 SER M N   1 
ATOM   6948 C CA  . SER E 3 203 ? -39.630 -17.464 -44.023 1.00 35.38  ? 202 SER M CA  1 
ATOM   6949 C C   . SER E 3 203 ? -40.047 -17.698 -42.577 1.00 39.84  ? 202 SER M C   1 
ATOM   6950 O O   . SER E 3 203 ? -41.064 -17.154 -42.130 1.00 40.05  ? 202 SER M O   1 
ATOM   6951 C CB  . SER E 3 203 ? -40.340 -18.451 -44.948 1.00 32.50  ? 202 SER M CB  1 
ATOM   6952 O OG  . SER E 3 203 ? -39.999 -19.789 -44.628 1.00 41.97  ? 202 SER M OG  1 
ATOM   6953 N N   . SER E 3 204 ? -39.279 -18.491 -41.837 1.00 37.43  ? 203 SER M N   1 
ATOM   6954 C CA  . SER E 3 204 ? -39.526 -18.766 -40.431 1.00 40.28  ? 203 SER M CA  1 
ATOM   6955 C C   . SER E 3 204 ? -38.192 -18.840 -39.706 1.00 37.31  ? 203 SER M C   1 
ATOM   6956 O O   . SER E 3 204 ? -37.166 -19.153 -40.322 1.00 37.79  ? 203 SER M O   1 
ATOM   6957 C CB  . SER E 3 204 ? -40.298 -20.081 -40.237 1.00 39.59  ? 203 SER M CB  1 
ATOM   6958 O OG  . SER E 3 204 ? -39.608 -21.169 -40.827 1.00 50.28  ? 203 SER M OG  1 
ATOM   6959 N N   . PRO E 3 205 ? -38.172 -18.546 -38.404 1.00 38.37  ? 204 PRO M N   1 
ATOM   6960 C CA  . PRO E 3 205 ? -36.905 -18.577 -37.663 1.00 39.82  ? 204 PRO M CA  1 
ATOM   6961 C C   . PRO E 3 205 ? -36.264 -19.957 -37.697 1.00 37.25  ? 204 PRO M C   1 
ATOM   6962 O O   . PRO E 3 205 ? -36.945 -20.985 -37.725 1.00 37.09  ? 204 PRO M O   1 
ATOM   6963 C CB  . PRO E 3 205 ? -37.319 -18.192 -36.238 1.00 41.92  ? 204 PRO M CB  1 
ATOM   6964 C CG  . PRO E 3 205 ? -38.581 -17.417 -36.410 1.00 42.55  ? 204 PRO M CG  1 
ATOM   6965 C CD  . PRO E 3 205 ? -39.282 -18.040 -37.579 1.00 42.10  ? 204 PRO M CD  1 
ATOM   6966 N N   . VAL E 3 206 ? -34.934 -19.969 -37.694 1.00 32.39  ? 205 VAL M N   1 
ATOM   6967 C CA  . VAL E 3 206 ? -34.151 -21.202 -37.694 1.00 36.85  ? 205 VAL M CA  1 
ATOM   6968 C C   . VAL E 3 206 ? -33.580 -21.397 -36.297 1.00 41.67  ? 205 VAL M C   1 
ATOM   6969 O O   . VAL E 3 206 ? -32.861 -20.531 -35.789 1.00 37.05  ? 205 VAL M O   1 
ATOM   6970 C CB  . VAL E 3 206 ? -33.032 -21.167 -38.745 1.00 36.16  ? 205 VAL M CB  1 
ATOM   6971 C CG1 . VAL E 3 206 ? -32.087 -22.344 -38.551 1.00 32.92  ? 205 VAL M CG1 1 
ATOM   6972 C CG2 . VAL E 3 206 ? -33.623 -21.175 -40.146 1.00 39.99  ? 205 VAL M CG2 1 
ATOM   6973 N N   . THR E 3 207 ? -33.887 -22.533 -35.681 1.00 39.24  ? 206 THR M N   1 
ATOM   6974 C CA  . THR E 3 207 ? -33.428 -22.842 -34.334 1.00 36.09  ? 206 THR M CA  1 
ATOM   6975 C C   . THR E 3 207 ? -32.405 -23.966 -34.390 1.00 37.54  ? 206 THR M C   1 
ATOM   6976 O O   . THR E 3 207 ? -32.672 -25.025 -34.969 1.00 35.72  ? 206 THR M O   1 
ATOM   6977 C CB  . THR E 3 207 ? -34.596 -23.242 -33.430 1.00 33.91  ? 206 THR M CB  1 
ATOM   6978 O OG1 . THR E 3 207 ? -35.490 -22.133 -33.278 1.00 39.63  ? 206 THR M OG1 1 
ATOM   6979 C CG2 . THR E 3 207 ? -34.089 -23.673 -32.060 1.00 36.71  ? 206 THR M CG2 1 
ATOM   6980 N N   . LYS E 3 208 ? -31.237 -23.735 -33.795 1.00 39.04  ? 207 LYS M N   1 
ATOM   6981 C CA  . LYS E 3 208 ? -30.228 -24.773 -33.634 1.00 31.69  ? 207 LYS M CA  1 
ATOM   6982 C C   . LYS E 3 208 ? -30.030 -25.003 -32.144 1.00 37.69  ? 207 LYS M C   1 
ATOM   6983 O O   . LYS E 3 208 ? -29.755 -24.056 -31.399 1.00 40.15  ? 207 LYS M O   1 
ATOM   6984 C CB  . LYS E 3 208 ? -28.909 -24.380 -34.304 1.00 38.86  ? 207 LYS M CB  1 
ATOM   6985 C CG  . LYS E 3 208 ? -28.968 -24.323 -35.830 1.00 39.50  ? 207 LYS M CG  1 
ATOM   6986 C CD  . LYS E 3 208 ? -29.298 -25.664 -36.465 1.00 41.15  ? 207 LYS M CD  1 
ATOM   6987 C CE  . LYS E 3 208 ? -29.249 -25.562 -37.985 1.00 44.74  ? 207 LYS M CE  1 
ATOM   6988 N NZ  . LYS E 3 208 ? -29.780 -26.778 -38.663 1.00 50.73  ? 207 LYS M NZ  1 
ATOM   6989 N N   . SER E 3 209 ? -30.163 -26.256 -31.711 1.00 34.22  ? 208 SER M N   1 
ATOM   6990 C CA  . SER E 3 209 ? -30.211 -26.570 -30.291 1.00 35.61  ? 208 SER M CA  1 
ATOM   6991 C C   . SER E 3 209 ? -29.443 -27.850 -29.997 1.00 37.12  ? 208 SER M C   1 
ATOM   6992 O O   . SER E 3 209 ? -29.070 -28.608 -30.896 1.00 34.55  ? 208 SER M O   1 
ATOM   6993 C CB  . SER E 3 209 ? -31.656 -26.715 -29.801 1.00 32.03  ? 208 SER M CB  1 
ATOM   6994 O OG  . SER E 3 209 ? -32.303 -27.805 -30.434 1.00 36.39  ? 208 SER M OG  1 
ATOM   6995 N N   . PHE E 3 210 ? -29.207 -28.072 -28.705 1.00 34.84  ? 209 PHE M N   1 
ATOM   6996 C CA  . PHE E 3 210 ? -28.619 -29.314 -28.224 1.00 35.89  ? 209 PHE M CA  1 
ATOM   6997 C C   . PHE E 3 210 ? -29.073 -29.564 -26.792 1.00 36.31  ? 209 PHE M C   1 
ATOM   6998 O O   . PHE E 3 210 ? -29.562 -28.663 -26.100 1.00 37.12  ? 209 PHE M O   1 
ATOM   6999 C CB  . PHE E 3 210 ? -27.085 -29.293 -28.312 1.00 37.24  ? 209 PHE M CB  1 
ATOM   7000 C CG  . PHE E 3 210 ? -26.427 -28.333 -27.357 1.00 44.11  ? 209 PHE M CG  1 
ATOM   7001 C CD1 . PHE E 3 210 ? -26.057 -28.738 -26.083 1.00 40.57  ? 209 PHE M CD1 1 
ATOM   7002 C CD2 . PHE E 3 210 ? -26.166 -27.029 -27.740 1.00 36.79  ? 209 PHE M CD2 1 
ATOM   7003 C CE1 . PHE E 3 210 ? -25.451 -27.855 -25.206 1.00 37.95  ? 209 PHE M CE1 1 
ATOM   7004 C CE2 . PHE E 3 210 ? -25.558 -26.143 -26.868 1.00 38.10  ? 209 PHE M CE2 1 
ATOM   7005 C CZ  . PHE E 3 210 ? -25.201 -26.557 -25.600 1.00 37.17  ? 209 PHE M CZ  1 
ATOM   7006 N N   . ASN E 3 211 ? -28.911 -30.812 -26.360 1.00 41.32  ? 210 ASN M N   1 
ATOM   7007 C CA  . ASN E 3 211 ? -29.177 -31.215 -24.986 1.00 45.21  ? 210 ASN M CA  1 
ATOM   7008 C C   . ASN E 3 211 ? -27.852 -31.328 -24.247 1.00 44.93  ? 210 ASN M C   1 
ATOM   7009 O O   . ASN E 3 211 ? -26.892 -31.904 -24.770 1.00 43.19  ? 210 ASN M O   1 
ATOM   7010 C CB  . ASN E 3 211 ? -29.934 -32.543 -24.928 1.00 54.17  ? 210 ASN M CB  1 
ATOM   7011 C CG  . ASN E 3 211 ? -31.312 -32.459 -25.556 1.00 53.15  ? 210 ASN M CG  1 
ATOM   7012 O OD1 . ASN E 3 211 ? -32.207 -31.801 -25.027 1.00 51.43  ? 210 ASN M OD1 1 
ATOM   7013 N ND2 . ASN E 3 211 ? -31.494 -33.139 -26.683 1.00 54.86  ? 210 ASN M ND2 1 
ATOM   7014 N N   . ARG E 3 212 ? -27.805 -30.770 -23.035 1.00 45.07  ? 211 ARG M N   1 
ATOM   7015 C CA  . ARG E 3 212 ? -26.551 -30.679 -22.295 1.00 47.09  ? 211 ARG M CA  1 
ATOM   7016 C C   . ARG E 3 212 ? -25.933 -32.051 -22.050 1.00 50.61  ? 211 ARG M C   1 
ATOM   7017 O O   . ARG E 3 212 ? -24.713 -32.217 -22.163 1.00 57.42  ? 211 ARG M O   1 
ATOM   7018 C CB  . ARG E 3 212 ? -26.786 -29.951 -20.973 1.00 42.15  ? 211 ARG M CB  1 
ATOM   7019 C CG  . ARG E 3 212 ? -25.602 -29.977 -20.026 1.00 43.92  ? 211 ARG M CG  1 
ATOM   7020 C CD  . ARG E 3 212 ? -25.901 -29.169 -18.776 1.00 42.34  ? 211 ARG M CD  1 
ATOM   7021 N NE  . ARG E 3 212 ? -27.190 -29.530 -18.198 1.00 44.70  ? 211 ARG M NE  1 
ATOM   7022 C CZ  . ARG E 3 212 ? -27.423 -30.639 -17.510 1.00 45.30  ? 211 ARG M CZ  1 
ATOM   7023 N NH1 . ARG E 3 212 ? -26.470 -31.529 -17.287 1.00 46.95  ? 211 ARG M NH1 1 
ATOM   7024 N NH2 . ARG E 3 212 ? -28.645 -30.863 -17.036 1.00 41.58  ? 211 ARG M NH2 1 
ATOM   7025 N N   . GLY E 3 213 ? -26.755 -33.047 -21.717 1.00 45.66  ? 212 GLY M N   1 
ATOM   7026 C CA  . GLY E 3 213 ? -26.218 -34.363 -21.417 1.00 53.53  ? 212 GLY M CA  1 
ATOM   7027 C C   . GLY E 3 213 ? -25.654 -35.083 -22.625 1.00 57.43  ? 212 GLY M C   1 
ATOM   7028 O O   . GLY E 3 213 ? -24.780 -35.944 -22.484 1.00 59.87  ? 212 GLY M O   1 
ATOM   7029 N N   . GLU E 3 214 ? -26.134 -34.747 -23.817 1.00 60.73  ? 213 GLU M N   1 
ATOM   7030 C CA  . GLU E 3 214 ? -25.698 -35.424 -25.033 1.00 60.32  ? 213 GLU M CA  1 
ATOM   7031 C C   . GLU E 3 214 ? -24.497 -34.723 -25.661 1.00 58.47  ? 213 GLU M C   1 
ATOM   7032 O O   . GLU E 3 214 ? -23.816 -35.284 -26.518 1.00 60.47  ? 213 GLU M O   1 
ATOM   7033 C CB  . GLU E 3 214 ? -26.850 -35.506 -26.036 1.00 60.05  ? 213 GLU M CB  1 
ATOM   7034 C CG  . GLU E 3 214 ? -28.082 -36.208 -25.489 1.00 60.80  ? 213 GLU M CG  1 
ATOM   7035 C CD  . GLU E 3 214 ? -29.242 -36.196 -26.463 1.00 76.40  ? 213 GLU M CD  1 
ATOM   7036 O OE1 . GLU E 3 214 ? -29.085 -35.638 -27.568 1.00 73.75  ? 213 GLU M OE1 1 
ATOM   7037 O OE2 . GLU E 3 214 ? -30.310 -36.744 -26.121 1.00 79.32  ? 213 GLU M OE2 1 
ATOM   7038 N N   . UNK F 2 1   ? -17.905 4.382   6.813   1.00 60.99  ? 3   UNK V N   1 
ATOM   7039 C CA  . UNK F 2 1   ? -18.640 5.497   7.398   1.00 59.94  ? 3   UNK V CA  1 
ATOM   7040 C C   . UNK F 2 1   ? -18.077 5.840   8.772   1.00 60.79  ? 3   UNK V C   1 
ATOM   7041 O O   . UNK F 2 1   ? -18.832 6.181   9.685   1.00 59.76  ? 3   UNK V O   1 
ATOM   7042 C CB  . UNK F 2 1   ? -20.130 5.163   7.501   1.00 63.01  ? 3   UNK V CB  1 
ATOM   7043 N N   . VAL F 2 2   ? -16.753 5.754   8.895   1.00 52.96  ? 4   VAL V N   1 
ATOM   7044 C CA  . VAL F 2 2   ? -16.039 5.964   10.156  1.00 50.92  ? 4   VAL V CA  1 
ATOM   7045 C C   . VAL F 2 2   ? -16.482 7.250   10.859  1.00 53.10  ? 4   VAL V C   1 
ATOM   7046 O O   . VAL F 2 2   ? -16.704 8.274   10.213  1.00 57.40  ? 4   VAL V O   1 
ATOM   7047 C CB  . VAL F 2 2   ? -14.514 5.977   9.912   1.00 53.99  ? 4   VAL V CB  1 
ATOM   7048 C CG1 . VAL F 2 2   ? -13.753 5.773   11.212  1.00 45.13  ? 4   VAL V CG1 1 
ATOM   7049 C CG2 . VAL F 2 2   ? -14.124 4.930   8.875   1.00 53.28  ? 4   VAL V CG2 1 
ATOM   7050 N N   . GLN F 2 3   ? -16.606 7.193   12.185  1.00 50.12  ? 5   GLN V N   1 
ATOM   7051 C CA  . GLN F 2 3   ? -17.007 8.346   12.979  1.00 53.76  ? 5   GLN V CA  1 
ATOM   7052 C C   . GLN F 2 3   ? -16.249 8.360   14.298  1.00 52.28  ? 5   GLN V C   1 
ATOM   7053 O O   . GLN F 2 3   ? -16.078 7.316   14.935  1.00 53.29  ? 5   GLN V O   1 
ATOM   7054 C CB  . GLN F 2 3   ? -18.518 8.331   13.255  1.00 59.43  ? 5   GLN V CB  1 
ATOM   7055 C CG  . GLN F 2 3   ? -19.071 9.623   13.840  1.00 52.63  ? 5   GLN V CG  1 
ATOM   7056 C CD  . GLN F 2 3   ? -19.303 10.697  12.794  1.00 68.46  ? 5   GLN V CD  1 
ATOM   7057 O OE1 . GLN F 2 3   ? -19.286 10.427  11.593  1.00 70.82  ? 5   GLN V OE1 1 
ATOM   7058 N NE2 . GLN F 2 3   ? -19.526 11.926  13.248  1.00 70.86  ? 5   GLN V NE2 1 
ATOM   7059 N N   . LEU F 2 4   ? -15.804 9.547   14.703  1.00 47.60  ? 6   LEU V N   1 
ATOM   7060 C CA  . LEU F 2 4   ? -15.121 9.722   15.983  1.00 45.73  ? 6   LEU V CA  1 
ATOM   7061 C C   . LEU F 2 4   ? -15.808 10.781  16.851  1.00 46.99  ? 6   LEU V C   1 
ATOM   7062 O O   . LEU F 2 4   ? -16.169 11.853  16.367  1.00 50.42  ? 6   LEU V O   1 
ATOM   7063 C CB  . LEU F 2 4   ? -13.655 10.093  15.757  1.00 51.69  ? 6   LEU V CB  1 
ATOM   7064 C CG  . LEU F 2 4   ? -12.877 9.194   14.787  1.00 46.80  ? 6   LEU V CG  1 
ATOM   7065 C CD1 . LEU F 2 4   ? -11.756 9.963   14.100  1.00 51.91  ? 6   LEU V CD1 1 
ATOM   7066 C CD2 . LEU F 2 4   ? -12.336 7.962   15.495  1.00 42.87  ? 6   LEU V CD2 1 
ATOM   7067 N N   . UNK F 2 5   ? -15.975 10.478  18.136  1.00 52.44  ? 7   UNK V N   1 
ATOM   7068 C CA  . UNK F 2 5   ? -16.584 11.416  19.074  1.00 50.10  ? 7   UNK V CA  1 
ATOM   7069 C C   . UNK F 2 5   ? -15.754 11.544  20.350  1.00 50.54  ? 7   UNK V C   1 
ATOM   7070 O O   . UNK F 2 5   ? -15.604 10.579  21.101  1.00 52.02  ? 7   UNK V O   1 
ATOM   7071 C CB  . UNK F 2 5   ? -18.011 10.979  19.416  1.00 44.45  ? 7   UNK V CB  1 
ATOM   7072 N N   . UNK F 2 6   ? -15.221 12.740  20.589  1.00 47.22  ? 8   UNK V N   1 
ATOM   7073 C CA  . UNK F 2 6   ? -14.394 12.996  21.767  1.00 53.43  ? 8   UNK V CA  1 
ATOM   7074 C C   . UNK F 2 6   ? -15.209 13.588  22.915  1.00 59.30  ? 8   UNK V C   1 
ATOM   7075 O O   . UNK F 2 6   ? -16.223 14.251  22.695  1.00 59.86  ? 8   UNK V O   1 
ATOM   7076 C CB  . UNK F 2 6   ? -13.239 13.933  21.412  1.00 50.67  ? 8   UNK V CB  1 
ATOM   7077 N N   . SER F 2 7   ? -14.751 13.349  24.141  1.00 52.07  ? 9   SER V N   1 
ATOM   7078 C CA  . SER F 2 7   ? -15.422 13.866  25.329  1.00 56.13  ? 9   SER V CA  1 
ATOM   7079 C C   . SER F 2 7   ? -14.472 13.918  26.520  1.00 58.41  ? 9   SER V C   1 
ATOM   7080 O O   . SER F 2 7   ? -13.382 13.347  26.481  1.00 54.91  ? 9   SER V O   1 
ATOM   7081 C CB  . SER F 2 7   ? -16.643 13.008  25.672  1.00 55.54  ? 9   SER V CB  1 
ATOM   7082 O OG  . SER F 2 7   ? -16.270 11.657  25.879  1.00 61.72  ? 9   SER V OG  1 
ATOM   7083 N N   . GLY F 2 8   ? -14.891 14.608  27.579  1.00 55.83  ? 10  GLY V N   1 
ATOM   7084 C CA  . GLY F 2 8   ? -14.131 14.690  28.810  1.00 51.89  ? 10  GLY V CA  1 
ATOM   7085 C C   . GLY F 2 8   ? -13.484 16.031  29.076  1.00 55.02  ? 10  GLY V C   1 
ATOM   7086 O O   . GLY F 2 8   ? -12.908 16.213  30.157  1.00 61.00  ? 10  GLY V O   1 
ATOM   7087 N N   . GLY F 2 9   ? -13.557 16.972  28.141  1.00 55.26  ? 11  GLY V N   1 
ATOM   7088 C CA  . GLY F 2 9   ? -12.967 18.277  28.353  1.00 56.08  ? 11  GLY V CA  1 
ATOM   7089 C C   . GLY F 2 9   ? -13.752 19.111  29.347  1.00 63.39  ? 11  GLY V C   1 
ATOM   7090 O O   . GLY F 2 9   ? -14.848 18.762  29.787  1.00 66.32  ? 11  GLY V O   1 
ATOM   7091 N N   . GLY F 2 10  ? -13.165 20.246  29.713  1.00 64.13  ? 12  GLY V N   1 
ATOM   7092 C CA  . GLY F 2 10  ? -13.810 21.161  30.637  1.00 64.08  ? 12  GLY V CA  1 
ATOM   7093 C C   . GLY F 2 10  ? -12.875 22.120  31.348  1.00 71.86  ? 12  GLY V C   1 
ATOM   7094 O O   . GLY F 2 10  ? -11.757 22.370  30.891  1.00 71.56  ? 12  GLY V O   1 
ATOM   7095 N N   . UNK F 2 11  ? -13.349 22.658  32.470  1.00 67.08  ? 13  UNK V N   1 
ATOM   7096 C CA  . UNK F 2 11  ? -12.585 23.607  33.275  1.00 73.26  ? 13  UNK V CA  1 
ATOM   7097 C C   . UNK F 2 11  ? -11.723 22.873  34.296  1.00 73.17  ? 13  UNK V C   1 
ATOM   7098 O O   . UNK F 2 11  ? -12.210 22.020  35.040  1.00 70.26  ? 13  UNK V O   1 
ATOM   7099 C CB  . UNK F 2 11  ? -13.521 24.589  33.982  1.00 71.49  ? 13  UNK V CB  1 
ATOM   7100 N N   . VAL F 2 12  ? -10.437 23.208  34.322  1.00 72.71  ? 14  VAL V N   1 
ATOM   7101 C CA  . VAL F 2 12  ? -9.479  22.540  35.191  1.00 73.61  ? 14  VAL V CA  1 
ATOM   7102 C C   . VAL F 2 12  ? -8.652  23.578  35.935  1.00 73.40  ? 14  VAL V C   1 
ATOM   7103 O O   . VAL F 2 12  ? -8.365  24.648  35.400  1.00 71.83  ? 14  VAL V O   1 
ATOM   7104 C CB  . VAL F 2 12  ? -8.551  21.610  34.386  1.00 73.55  ? 14  VAL V CB  1 
ATOM   7105 C CG1 . VAL F 2 12  ? -7.856  20.613  35.295  1.00 73.85  ? 14  VAL V CG1 1 
ATOM   7106 C CG2 . VAL F 2 12  ? -9.309  20.914  33.290  1.00 74.70  ? 14  VAL V CG2 1 
ATOM   7107 N N   . GLN F 2 13  ? -8.269  23.265  37.168  1.00 70.87  ? 15  GLN V N   1 
ATOM   7108 C CA  . GLN F 2 13  ? -7.359  24.128  37.907  1.00 75.31  ? 15  GLN V CA  1 
ATOM   7109 C C   . GLN F 2 13  ? -5.933  23.806  37.476  1.00 72.84  ? 15  GLN V C   1 
ATOM   7110 O O   . GLN F 2 13  ? -5.641  22.678  37.078  1.00 71.36  ? 15  GLN V O   1 
ATOM   7111 C CB  . GLN F 2 13  ? -7.520  23.953  39.419  1.00 81.34  ? 15  GLN V CB  1 
ATOM   7112 C CG  . GLN F 2 13  ? -8.898  24.315  39.955  1.00 83.75  ? 15  GLN V CG  1 
ATOM   7113 C CD  . GLN F 2 13  ? -9.901  23.189  39.809  1.00 84.60  ? 15  GLN V CD  1 
ATOM   7114 O OE1 . GLN F 2 13  ? -9.580  22.119  39.292  1.00 80.45  ? 15  GLN V OE1 1 
ATOM   7115 N NE2 . GLN F 2 13  ? -11.124 23.423  40.269  1.00 81.14  ? 15  GLN V NE2 1 
ATOM   7116 N N   . UNK F 2 14  ? -5.052  24.798  37.551  1.00 70.02  ? 16  UNK V N   1 
ATOM   7117 C CA  . UNK F 2 14  ? -3.659  24.612  37.159  1.00 65.25  ? 16  UNK V CA  1 
ATOM   7118 C C   . UNK F 2 14  ? -2.968  23.550  38.011  1.00 71.08  ? 16  UNK V C   1 
ATOM   7119 O O   . UNK F 2 14  ? -2.590  23.804  39.155  1.00 81.05  ? 16  UNK V O   1 
ATOM   7120 C CB  . UNK F 2 14  ? -2.898  25.936  37.254  1.00 69.86  ? 16  UNK V CB  1 
ATOM   7121 N N   . GLY F 2 15  ? -2.815  22.356  37.444  1.00 73.78  ? 17  GLY V N   1 
ATOM   7122 C CA  . GLY F 2 15  ? -2.128  21.270  38.119  1.00 70.43  ? 17  GLY V CA  1 
ATOM   7123 C C   . GLY F 2 15  ? -3.006  20.104  38.535  1.00 68.65  ? 17  GLY V C   1 
ATOM   7124 O O   . GLY F 2 15  ? -2.590  19.268  39.337  1.00 68.28  ? 17  GLY V O   1 
ATOM   7125 N N   . UNK F 2 16  ? -4.217  20.040  37.992  1.00 69.07  ? 18  UNK V N   1 
ATOM   7126 C CA  . UNK F 2 16  ? -5.151  18.974  38.348  1.00 72.58  ? 18  UNK V CA  1 
ATOM   7127 C C   . UNK F 2 16  ? -5.046  17.793  37.385  1.00 75.22  ? 18  UNK V C   1 
ATOM   7128 O O   . UNK F 2 16  ? -3.943  17.406  36.993  1.00 74.83  ? 18  UNK V O   1 
ATOM   7129 C CB  . UNK F 2 16  ? -6.585  19.505  38.380  1.00 76.93  ? 18  UNK V CB  1 
ATOM   7130 N N   . SER F 2 17  ? -6.189  17.226  37.007  1.00 75.33  ? 19  SER V N   1 
ATOM   7131 C CA  . SER F 2 17  ? -6.202  16.007  36.201  1.00 69.30  ? 19  SER V CA  1 
ATOM   7132 C C   . SER F 2 17  ? -7.491  15.820  35.401  1.00 65.85  ? 19  SER V C   1 
ATOM   7133 O O   . SER F 2 17  ? -8.583  16.093  35.896  1.00 68.87  ? 19  SER V O   1 
ATOM   7134 C CB  . SER F 2 17  ? -5.984  14.788  37.099  1.00 67.47  ? 19  SER V CB  1 
ATOM   7135 O OG  . SER F 2 17  ? -6.298  13.588  36.414  1.00 70.82  ? 19  SER V OG  1 
ATOM   7136 N N   . LEU F 2 18  ? -7.355  15.353  34.162  1.00 65.30  ? 20  LEU V N   1 
ATOM   7137 C CA  . LEU F 2 18  ? -8.516  15.018  33.343  1.00 60.43  ? 20  LEU V CA  1 
ATOM   7138 C C   . LEU F 2 18  ? -8.289  13.716  32.585  1.00 59.61  ? 20  LEU V C   1 
ATOM   7139 O O   . LEU F 2 18  ? -7.158  13.248  32.459  1.00 62.31  ? 20  LEU V O   1 
ATOM   7140 C CB  . LEU F 2 18  ? -8.851  16.123  32.340  1.00 67.56  ? 20  LEU V CB  1 
ATOM   7141 C CG  . LEU F 2 18  ? -9.728  17.290  32.799  1.00 71.26  ? 20  LEU V CG  1 
ATOM   7142 C CD1 . LEU F 2 18  ? -10.153 18.100  31.580  1.00 66.74  ? 20  LEU V CD1 1 
ATOM   7143 C CD2 . LEU F 2 18  ? -10.922 16.846  33.633  1.00 68.58  ? 20  LEU V CD2 1 
ATOM   7144 N N   . UNK F 2 19  ? -9.374  13.142  32.074  1.00 54.00  ? 21  UNK V N   1 
ATOM   7145 C CA  . UNK F 2 19  ? -9.293  11.927  31.272  1.00 52.66  ? 21  UNK V CA  1 
ATOM   7146 C C   . UNK F 2 19  ? -10.178 12.018  30.031  1.00 52.58  ? 21  UNK V C   1 
ATOM   7147 O O   . UNK F 2 19  ? -11.352 11.644  30.067  1.00 49.54  ? 21  UNK V O   1 
ATOM   7148 C CB  . UNK F 2 19  ? -9.689  10.708  32.109  1.00 46.50  ? 21  UNK V CB  1 
ATOM   7149 N N   . LEU F 2 20  ? -9.612  12.518  28.937  1.00 52.78  ? 22  LEU V N   1 
ATOM   7150 C CA  . LEU F 2 20  ? -10.334 12.610  27.671  1.00 51.09  ? 22  LEU V CA  1 
ATOM   7151 C C   . LEU F 2 20  ? -10.529 11.225  27.067  1.00 50.05  ? 22  LEU V C   1 
ATOM   7152 O O   . LEU F 2 20  ? -9.682  10.345  27.223  1.00 52.59  ? 22  LEU V O   1 
ATOM   7153 C CB  . LEU F 2 20  ? -9.595  13.509  26.673  1.00 44.83  ? 22  LEU V CB  1 
ATOM   7154 C CG  . LEU F 2 20  ? -9.709  15.038  26.730  1.00 52.48  ? 22  LEU V CG  1 
ATOM   7155 C CD1 . LEU F 2 20  ? -9.767  15.582  28.153  1.00 52.88  ? 22  LEU V CD1 1 
ATOM   7156 C CD2 . LEU F 2 20  ? -8.566  15.676  25.953  1.00 48.66  ? 22  LEU V CD2 1 
ATOM   7157 N N   . SER F 2 21  ? -11.652 11.032  26.381  1.00 49.05  ? 23  SER V N   1 
ATOM   7158 C CA  . SER F 2 21  ? -11.945 9.775   25.712  1.00 50.51  ? 23  SER V CA  1 
ATOM   7159 C C   . SER F 2 21  ? -12.382 10.047  24.281  1.00 49.71  ? 23  SER V C   1 
ATOM   7160 O O   . SER F 2 21  ? -12.878 11.128  23.951  1.00 51.89  ? 23  SER V O   1 
ATOM   7161 C CB  . SER F 2 21  ? -13.034 8.981   26.447  1.00 51.34  ? 23  SER V CB  1 
ATOM   7162 O OG  . SER F 2 21  ? -14.275 9.663   26.407  1.00 53.93  ? 23  SER V OG  1 
ATOM   7163 N N   . CYS F 2 22  ? -12.188 9.046   23.431  1.00 44.66  ? 24  CYS V N   1 
ATOM   7164 C CA  . CYS F 2 22  ? -12.685 9.097   22.064  1.00 46.10  ? 24  CYS V CA  1 
ATOM   7165 C C   . CYS F 2 22  ? -13.283 7.759   21.663  1.00 41.54  ? 24  CYS V C   1 
ATOM   7166 O O   . CYS F 2 22  ? -12.588 6.746   21.626  1.00 38.95  ? 24  CYS V O   1 
ATOM   7167 C CB  . CYS F 2 22  ? -11.574 9.480   21.089  1.00 46.74  ? 24  CYS V CB  1 
ATOM   7168 S SG  . CYS F 2 22  ? -12.126 9.537   19.369  1.00 44.34  ? 24  CYS V SG  1 
ATOM   7169 N N   . UNK F 2 23  ? -14.576 7.763   21.363  1.00 47.92  ? 25  UNK V N   1 
ATOM   7170 C CA  . UNK F 2 23  ? -15.253 6.554   20.917  1.00 49.49  ? 25  UNK V CA  1 
ATOM   7171 C C   . UNK F 2 23  ? -15.366 6.554   19.398  1.00 44.99  ? 25  UNK V C   1 
ATOM   7172 O O   . UNK F 2 23  ? -15.772 7.548   18.795  1.00 50.61  ? 25  UNK V O   1 
ATOM   7173 C CB  . UNK F 2 23  ? -16.637 6.439   21.556  1.00 53.33  ? 25  UNK V CB  1 
ATOM   7174 N N   . ALA F 2 24  ? -15.000 5.436   18.782  1.00 45.89  ? 26  ALA V N   1 
ATOM   7175 C CA  . ALA F 2 24  ? -15.080 5.307   17.335  1.00 47.07  ? 26  ALA V CA  1 
ATOM   7176 C C   . ALA F 2 24  ? -16.271 4.445   16.939  1.00 49.97  ? 26  ALA V C   1 
ATOM   7177 O O   . ALA F 2 24  ? -16.637 3.511   17.652  1.00 52.81  ? 26  ALA V O   1 
ATOM   7178 C CB  . ALA F 2 24  ? -13.791 4.723   16.782  1.00 38.24  ? 26  ALA V CB  1 
ATOM   7179 N N   . UNK F 2 25  ? -16.873 4.767   15.800  1.00 50.33  ? 27  UNK V N   1 
ATOM   7180 C CA  . UNK F 2 25  ? -17.997 3.997   15.284  1.00 48.21  ? 27  UNK V CA  1 
ATOM   7181 C C   . UNK F 2 25  ? -17.778 3.649   13.815  1.00 49.49  ? 27  UNK V C   1 
ATOM   7182 O O   . UNK F 2 25  ? -16.916 4.237   13.157  1.00 54.24  ? 27  UNK V O   1 
ATOM   7183 C CB  . UNK F 2 25  ? -19.307 4.768   15.455  1.00 53.95  ? 27  UNK V CB  1 
ATOM   7184 N N   . UNK F 2 26  ? -18.552 2.679   13.331  1.00 49.74  ? 28  UNK V N   1 
ATOM   7185 C CA  . UNK F 2 26  ? -18.539 2.224   11.937  1.00 49.99  ? 28  UNK V CA  1 
ATOM   7186 C C   . UNK F 2 26  ? -17.264 1.477   11.540  1.00 52.44  ? 28  UNK V C   1 
ATOM   7187 O O   . UNK F 2 26  ? -17.165 0.996   10.410  1.00 49.89  ? 28  UNK V O   1 
ATOM   7188 C CB  . UNK F 2 26  ? -18.763 3.399   10.984  1.00 56.88  ? 28  UNK V CB  1 
ATOM   7189 N N   . UNK F 2 27  ? -16.311 1.371   12.461  1.00 53.72  ? 29  UNK V N   1 
ATOM   7190 C CA  . UNK F 2 27  ? -15.093 0.600   12.224  1.00 49.12  ? 29  UNK V CA  1 
ATOM   7191 C C   . UNK F 2 27  ? -14.340 0.374   13.529  1.00 52.74  ? 29  UNK V C   1 
ATOM   7192 O O   . UNK F 2 27  ? -14.352 1.228   14.416  1.00 41.28  ? 29  UNK V O   1 
ATOM   7193 C CB  . UNK F 2 27  ? -14.187 1.307   11.212  1.00 42.39  ? 29  UNK V CB  1 
ATOM   7194 N N   . UNK F 2 28  ? -13.690 -0.779  13.642  1.00 54.14  ? 30  UNK V N   1 
ATOM   7195 C CA  . UNK F 2 28  ? -12.881 -1.082  14.816  1.00 49.07  ? 30  UNK V CA  1 
ATOM   7196 C C   . UNK F 2 28  ? -11.532 -0.378  14.710  1.00 51.63  ? 30  UNK V C   1 
ATOM   7197 O O   . UNK F 2 28  ? -10.916 -0.360  13.643  1.00 47.70  ? 30  UNK V O   1 
ATOM   7198 C CB  . UNK F 2 28  ? -12.688 -2.592  14.967  1.00 48.62  ? 30  UNK V CB  1 
ATOM   7199 N N   . UNK F 2 29  ? -11.079 0.204   15.815  1.00 47.09  ? 31  UNK V N   1 
ATOM   7200 C CA  . UNK F 2 29  ? -9.813  0.930   15.833  0.84 47.06  ? 31  UNK V CA  1 
ATOM   7201 C C   . UNK F 2 29  ? -8.674  0.011   16.259  0.97 44.15  ? 31  UNK V C   1 
ATOM   7202 O O   . UNK F 2 29  ? -7.593  0.472   16.626  0.46 43.48  ? 31  UNK V O   1 
ATOM   7203 C CB  . UNK F 2 29  ? -9.899  2.135   16.770  1.00 50.69  ? 31  UNK V CB  1 
ATOM   7204 N N   . UNK F 2 30  ? -8.923  -1.293  16.196  1.00 41.70  ? 32  UNK V N   1 
ATOM   7205 C CA  . UNK F 2 30  ? -7.975  -2.286  16.688  1.00 42.27  ? 32  UNK V CA  1 
ATOM   7206 C C   . UNK F 2 30  ? -6.728  -2.385  15.811  1.00 42.20  ? 32  UNK V C   1 
ATOM   7207 O O   . UNK F 2 30  ? -5.610  -2.447  16.325  1.00 36.29  ? 32  UNK V O   1 
ATOM   7208 C CB  . UNK F 2 30  ? -8.651  -3.655  16.787  1.00 39.60  ? 32  UNK V CB  1 
ATOM   7209 N N   . UNK F 2 31  ? -6.921  -2.397  14.496  1.00 43.60  ? 33  UNK V N   1 
ATOM   7210 C CA  . UNK F 2 31  ? -5.817  -2.598  13.561  1.00 38.44  ? 33  UNK V CA  1 
ATOM   7211 C C   . UNK F 2 31  ? -5.145  -1.289  13.155  1.00 41.75  ? 33  UNK V C   1 
ATOM   7212 O O   . UNK F 2 31  ? -4.276  -1.280  12.280  1.00 42.14  ? 33  UNK V O   1 
ATOM   7213 C CB  . UNK F 2 31  ? -6.312  -3.331  12.310  1.00 33.95  ? 33  UNK V CB  1 
ATOM   7214 N N   . UNK F 2 32  ? -5.541  -0.190  13.785  1.00 35.88  ? 34  UNK V N   1 
ATOM   7215 C CA  . UNK F 2 32  ? -5.039  1.122   13.394  1.00 37.64  ? 34  UNK V CA  1 
ATOM   7216 C C   . UNK F 2 32  ? -4.586  1.949   14.591  1.00 42.62  ? 34  UNK V C   1 
ATOM   7217 O O   . UNK F 2 32  ? -5.153  1.860   15.681  1.00 41.80  ? 34  UNK V O   1 
ATOM   7218 C CB  . UNK F 2 32  ? -6.110  1.887   12.614  1.00 37.11  ? 34  UNK V CB  1 
ATOM   7219 N N   . UNK F 2 33  ? -3.551  2.752   14.374  1.00 40.32  ? 35  UNK V N   1 
ATOM   7220 C CA  . UNK F 2 33  ? -3.066  3.671   15.391  1.00 36.61  ? 35  UNK V CA  1 
ATOM   7221 C C   . UNK F 2 33  ? -4.062  4.810   15.570  1.00 38.83  ? 35  UNK V C   1 
ATOM   7222 O O   . UNK F 2 33  ? -4.678  5.258   14.603  1.00 37.88  ? 35  UNK V O   1 
ATOM   7223 C CB  . UNK F 2 33  ? -1.690  4.222   15.013  1.00 34.84  ? 35  UNK V CB  1 
ATOM   7224 N N   . UNK F 2 34  ? -4.224  5.269   16.806  1.00 41.23  ? 36  UNK V N   1 
ATOM   7225 C CA  . UNK F 2 34  ? -5.088  6.409   17.091  1.00 41.82  ? 36  UNK V CA  1 
ATOM   7226 C C   . UNK F 2 34  ? -4.259  7.538   17.691  1.00 36.84  ? 36  UNK V C   1 
ATOM   7227 O O   . UNK F 2 34  ? -3.486  7.313   18.625  1.00 37.00  ? 36  UNK V O   1 
ATOM   7228 C CB  . UNK F 2 34  ? -6.219  6.010   18.040  1.00 32.61  ? 36  UNK V CB  1 
ATOM   7229 N N   . UNK F 2 35  ? -4.416  8.749   17.166  1.00 38.50  ? 37  UNK V N   1 
ATOM   7230 C CA  . UNK F 2 35  ? -3.562  9.851   17.591  1.00 40.30  ? 37  UNK V CA  1 
ATOM   7231 C C   . UNK F 2 35  ? -4.350  11.038  18.132  1.00 39.78  ? 37  UNK V C   1 
ATOM   7232 O O   . UNK F 2 35  ? -5.373  11.438  17.581  1.00 43.42  ? 37  UNK V O   1 
ATOM   7233 C CB  . UNK F 2 35  ? -2.675  10.308  16.431  1.00 34.47  ? 37  UNK V CB  1 
ATOM   7234 N N   . TRP F 2 36  ? -3.857  11.597  19.231  1.00 39.09  ? 38  TRP V N   1 
ATOM   7235 C CA  . TRP F 2 36  ? -4.409  12.819  19.795  1.00 37.81  ? 38  TRP V CA  1 
ATOM   7236 C C   . TRP F 2 36  ? -3.581  14.016  19.359  1.00 44.01  ? 38  TRP V C   1 
ATOM   7237 O O   . TRP F 2 36  ? -2.352  14.013  19.504  1.00 47.15  ? 38  TRP V O   1 
ATOM   7238 C CB  . TRP F 2 36  ? -4.447  12.750  21.321  1.00 42.12  ? 38  TRP V CB  1 
ATOM   7239 C CG  . TRP F 2 36  ? -5.482  11.832  21.869  1.00 45.72  ? 38  TRP V CG  1 
ATOM   7240 C CD1 . TRP F 2 36  ? -5.323  10.517  22.191  1.00 43.42  ? 38  TRP V CD1 1 
ATOM   7241 C CD2 . TRP F 2 36  ? -6.841  12.161  22.181  1.00 47.22  ? 38  TRP V CD2 1 
ATOM   7242 N NE1 . TRP F 2 36  ? -6.500  10.003  22.676  1.00 45.38  ? 38  TRP V NE1 1 
ATOM   7243 C CE2 . TRP F 2 36  ? -7.448  10.993  22.680  1.00 51.01  ? 38  TRP V CE2 1 
ATOM   7244 C CE3 . TRP F 2 36  ? -7.604  13.328  22.081  1.00 46.40  ? 38  TRP V CE3 1 
ATOM   7245 C CZ2 . TRP F 2 36  ? -8.782  10.957  23.080  1.00 51.07  ? 38  TRP V CZ2 1 
ATOM   7246 C CZ3 . TRP F 2 36  ? -8.929  13.292  22.478  1.00 49.63  ? 38  TRP V CZ3 1 
ATOM   7247 C CH2 . TRP F 2 36  ? -9.504  12.115  22.972  1.00 47.44  ? 38  TRP V CH2 1 
ATOM   7248 N N   . UNK F 2 37  ? -4.266  15.026  18.830  1.00 40.82  ? 39  UNK V N   1 
ATOM   7249 C CA  . UNK F 2 37  ? -3.654  16.303  18.487  1.00 39.32  ? 39  UNK V CA  1 
ATOM   7250 C C   . UNK F 2 37  ? -4.416  17.419  19.192  1.00 45.72  ? 39  UNK V C   1 
ATOM   7251 O O   . UNK F 2 37  ? -5.521  17.194  19.684  1.00 45.23  ? 39  UNK V O   1 
ATOM   7252 C CB  . UNK F 2 37  ? -3.660  16.521  16.973  1.00 38.81  ? 39  UNK V CB  1 
ATOM   7253 N N   . ARG F 2 38  ? -3.837  18.614  19.250  1.00 38.29  ? 40  ARG V N   1 
ATOM   7254 C CA  . ARG F 2 38  ? -4.524  19.735  19.883  1.00 47.94  ? 40  ARG V CA  1 
ATOM   7255 C C   . ARG F 2 38  ? -4.310  21.038  19.126  1.00 51.47  ? 40  ARG V C   1 
ATOM   7256 O O   . ARG F 2 38  ? -3.291  21.233  18.463  1.00 47.57  ? 40  ARG V O   1 
ATOM   7257 C CB  . ARG F 2 38  ? -4.076  19.894  21.339  1.00 51.48  ? 40  ARG V CB  1 
ATOM   7258 C CG  . ARG F 2 38  ? -2.665  20.427  21.528  1.00 48.27  ? 40  ARG V CG  1 
ATOM   7259 C CD  . ARG F 2 38  ? -2.276  20.378  22.998  1.00 45.43  ? 40  ARG V CD  1 
ATOM   7260 N NE  . ARG F 2 38  ? -0.891  20.770  23.230  1.00 50.90  ? 40  ARG V NE  1 
ATOM   7261 C CZ  . ARG F 2 38  ? -0.320  20.813  24.426  1.00 52.51  ? 40  ARG V CZ  1 
ATOM   7262 N NH1 . ARG F 2 38  ? -0.988  20.490  25.522  1.00 48.46  ? 40  ARG V NH1 1 
ATOM   7263 N NH2 . ARG F 2 38  ? 0.953   21.185  24.525  1.00 43.36  ? 40  ARG V NH2 1 
ATOM   7264 N N   . GLN F 2 39  ? -5.293  21.924  19.232  1.00 51.57  ? 41  GLN V N   1 
ATOM   7265 C CA  . GLN F 2 39  ? -5.267  23.200  18.538  1.00 55.14  ? 41  GLN V CA  1 
ATOM   7266 C C   . GLN F 2 39  ? -5.668  24.317  19.495  1.00 54.96  ? 41  GLN V C   1 
ATOM   7267 O O   . GLN F 2 39  ? -6.772  24.317  20.041  1.00 54.70  ? 41  GLN V O   1 
ATOM   7268 C CB  . GLN F 2 39  ? -6.194  23.169  17.321  1.00 49.51  ? 41  GLN V CB  1 
ATOM   7269 C CG  . GLN F 2 39  ? -5.924  24.260  16.301  1.00 56.89  ? 41  GLN V CG  1 
ATOM   7270 C CD  . GLN F 2 39  ? -6.838  24.170  15.095  1.00 55.15  ? 41  GLN V CD  1 
ATOM   7271 O OE1 . GLN F 2 39  ? -7.785  23.384  15.076  1.00 55.74  ? 41  GLN V OE1 1 
ATOM   7272 N NE2 . GLN F 2 39  ? -6.558  24.978  14.078  1.00 53.48  ? 41  GLN V NE2 1 
ATOM   7273 N N   . UNK F 2 40  ? -4.748  25.248  19.718  1.00 57.66  ? 42  UNK V N   1 
ATOM   7274 C CA  . UNK F 2 40  ? -5.027  26.437  20.509  1.00 60.40  ? 42  UNK V CA  1 
ATOM   7275 C C   . UNK F 2 40  ? -5.515  27.545  19.582  1.00 63.35  ? 42  UNK V C   1 
ATOM   7276 O O   . UNK F 2 40  ? -5.204  27.510  18.390  1.00 63.07  ? 42  UNK V O   1 
ATOM   7277 C CB  . UNK F 2 40  ? -3.778  26.878  21.277  1.00 58.88  ? 42  UNK V CB  1 
ATOM   7278 N N   . PRO F 2 41  ? -6.291  28.505  20.115  1.00 69.59  ? 43  PRO V N   1 
ATOM   7279 C CA  . PRO F 2 41  ? -6.850  29.592  19.303  1.00 67.64  ? 43  PRO V CA  1 
ATOM   7280 C C   . PRO F 2 41  ? -5.805  30.303  18.442  1.00 64.84  ? 43  PRO V C   1 
ATOM   7281 O O   . PRO F 2 41  ? -4.850  30.870  18.974  1.00 65.15  ? 43  PRO V O   1 
ATOM   7282 C CB  . PRO F 2 41  ? -7.421  30.544  20.354  1.00 72.51  ? 43  PRO V CB  1 
ATOM   7283 C CG  . PRO F 2 41  ? -7.837  29.643  21.461  1.00 69.83  ? 43  PRO V CG  1 
ATOM   7284 C CD  . PRO F 2 41  ? -6.814  28.533  21.494  1.00 68.78  ? 43  PRO V CD  1 
ATOM   7285 N N   . GLY F 2 42  ? -5.985  30.254  17.126  1.00 68.50  ? 44  GLY V N   1 
ATOM   7286 C CA  . GLY F 2 42  ? -5.063  30.886  16.201  1.00 62.00  ? 44  GLY V CA  1 
ATOM   7287 C C   . GLY F 2 42  ? -3.791  30.100  15.941  1.00 66.62  ? 44  GLY V C   1 
ATOM   7288 O O   . GLY F 2 42  ? -2.748  30.678  15.635  1.00 66.31  ? 44  GLY V O   1 
ATOM   7289 N N   . UNK F 2 43  ? -3.876  28.780  16.061  1.00 65.15  ? 45  UNK V N   1 
ATOM   7290 C CA  . UNK F 2 43  ? -2.718  27.919  15.849  1.00 61.23  ? 45  UNK V CA  1 
ATOM   7291 C C   . UNK F 2 43  ? -3.103  26.692  15.030  1.00 61.04  ? 45  UNK V C   1 
ATOM   7292 O O   . UNK F 2 43  ? -4.280  26.475  14.741  1.00 59.12  ? 45  UNK V O   1 
ATOM   7293 C CB  . UNK F 2 43  ? -2.109  27.494  17.187  1.00 56.52  ? 45  UNK V CB  1 
ATOM   7294 N N   . UNK F 2 44  ? -2.106  25.895  14.657  1.00 58.72  ? 46  UNK V N   1 
ATOM   7295 C CA  . UNK F 2 44  ? -2.340  24.683  13.879  1.00 61.12  ? 46  UNK V CA  1 
ATOM   7296 C C   . UNK F 2 44  ? -2.438  23.474  14.801  1.00 55.56  ? 46  UNK V C   1 
ATOM   7297 O O   . UNK F 2 44  ? -1.951  23.509  15.933  1.00 53.14  ? 46  UNK V O   1 
ATOM   7298 C CB  . UNK F 2 44  ? -1.226  24.478  12.851  1.00 57.43  ? 46  UNK V CB  1 
ATOM   7299 N N   . ARG F 2 45  ? -3.067  22.408  14.315  1.00 53.51  ? 47  ARG V N   1 
ATOM   7300 C CA  . ARG F 2 45  ? -3.236  21.194  15.106  1.00 51.82  ? 47  ARG V CA  1 
ATOM   7301 C C   . ARG F 2 45  ? -1.888  20.531  15.380  1.00 53.05  ? 47  ARG V C   1 
ATOM   7302 O O   . ARG F 2 45  ? -1.289  19.918  14.495  1.00 51.00  ? 47  ARG V O   1 
ATOM   7303 C CB  . ARG F 2 45  ? -4.186  20.223  14.398  1.00 50.09  ? 47  ARG V CB  1 
ATOM   7304 C CG  . ARG F 2 45  ? -5.610  20.749  14.281  1.00 51.83  ? 47  ARG V CG  1 
ATOM   7305 C CD  . ARG F 2 45  ? -6.576  19.691  13.771  1.00 51.93  ? 47  ARG V CD  1 
ATOM   7306 N NE  . ARG F 2 45  ? -7.803  20.286  13.253  1.00 57.65  ? 47  ARG V NE  1 
ATOM   7307 C CZ  . ARG F 2 45  ? -8.834  19.596  12.784  1.00 58.73  ? 47  ARG V CZ  1 
ATOM   7308 N NH1 . ARG F 2 45  ? -8.823  18.274  12.751  1.00 56.35  ? 47  ARG V NH1 1 
ATOM   7309 N NH2 . ARG F 2 45  ? -9.905  20.250  12.342  1.00 57.75  ? 47  ARG V NH2 1 
ATOM   7310 N N   . GLU F 2 46  ? -1.420  20.667  16.617  1.00 58.50  ? 48  GLU V N   1 
ATOM   7311 C CA  . GLU F 2 46  ? -0.140  20.105  17.033  1.00 49.38  ? 48  GLU V CA  1 
ATOM   7312 C C   . GLU F 2 46  ? -0.297  18.676  17.530  1.00 41.86  ? 48  GLU V C   1 
ATOM   7313 O O   . GLU F 2 46  ? -1.282  18.350  18.187  1.00 41.04  ? 48  GLU V O   1 
ATOM   7314 C CB  . GLU F 2 46  ? 0.487   20.965  18.132  1.00 52.69  ? 48  GLU V CB  1 
ATOM   7315 C CG  . GLU F 2 46  ? 0.461   22.455  17.842  1.00 58.99  ? 48  GLU V CG  1 
ATOM   7316 C CD  . GLU F 2 46  ? 1.687   22.928  17.089  1.00 69.36  ? 48  GLU V CD  1 
ATOM   7317 O OE1 . GLU F 2 46  ? 2.264   23.960  17.492  1.00 68.66  ? 48  GLU V OE1 1 
ATOM   7318 O OE2 . GLU F 2 46  ? 2.081   22.269  16.105  1.00 72.96  ? 48  GLU V OE2 1 
ATOM   7319 N N   . UNK F 2 47  ? 0.681   17.831  17.224  1.00 35.71  ? 49  UNK V N   1 
ATOM   7320 C CA  . UNK F 2 47  ? 0.665   16.450  17.689  1.00 36.91  ? 49  UNK V CA  1 
ATOM   7321 C C   . UNK F 2 47  ? 0.808   16.403  19.206  1.00 35.74  ? 49  UNK V C   1 
ATOM   7322 O O   . UNK F 2 47  ? 1.632   17.115  19.781  1.00 35.89  ? 49  UNK V O   1 
ATOM   7323 C CB  . UNK F 2 47  ? 1.783   15.642  17.025  1.00 30.91  ? 49  UNK V CB  1 
ATOM   7324 N N   . VAL F 2 48  ? -0.006  15.574  19.852  1.00 35.83  ? 50  VAL V N   1 
ATOM   7325 C CA  . VAL F 2 48  ? 0.074   15.398  21.296  1.00 40.37  ? 50  VAL V CA  1 
ATOM   7326 C C   . VAL F 2 48  ? 0.619   14.015  21.602  1.00 39.79  ? 50  VAL V C   1 
ATOM   7327 O O   . VAL F 2 48  ? 1.658   13.874  22.248  1.00 37.12  ? 50  VAL V O   1 
ATOM   7328 C CB  . VAL F 2 48  ? -1.292  15.598  21.973  1.00 38.49  ? 50  VAL V CB  1 
ATOM   7329 C CG1 . VAL F 2 48  ? -1.191  15.313  23.464  1.00 42.15  ? 50  VAL V CG1 1 
ATOM   7330 C CG2 . VAL F 2 48  ? -1.805  16.998  21.725  1.00 41.19  ? 50  VAL V CG2 1 
ATOM   7331 N N   . UNK F 2 49  ? -0.088  12.994  21.132  1.00 38.49  ? 51  UNK V N   1 
ATOM   7332 C CA  . UNK F 2 49  ? 0.306   11.619  21.433  1.00 35.55  ? 51  UNK V CA  1 
ATOM   7333 C C   . UNK F 2 49  ? -0.250  10.634  20.416  1.00 36.55  ? 51  UNK V C   1 
ATOM   7334 O O   . UNK F 2 49  ? -1.086  10.988  19.592  1.00 36.32  ? 51  UNK V O   1 
ATOM   7335 C CB  . UNK F 2 49  ? -0.152  11.227  22.840  1.00 32.02  ? 51  UNK V CB  1 
ATOM   7336 N N   . UNK F 2 50  ? 0.218   9.394   20.481  1.00 28.47  ? 52  UNK V N   1 
ATOM   7337 C CA  . UNK F 2 50  ? -0.262  8.365   19.572  1.00 35.20  ? 52  UNK V CA  1 
ATOM   7338 C C   . UNK F 2 50  ? -0.163  6.988   20.208  1.00 35.80  ? 52  UNK V C   1 
ATOM   7339 O O   . UNK F 2 50  ? 0.889   6.602   20.726  1.00 36.64  ? 52  UNK V O   1 
ATOM   7340 C CB  . UNK F 2 50  ? 0.525   8.399   18.262  1.00 34.05  ? 52  UNK V CB  1 
ATOM   7341 N N   . UNK F 2 51  ? -1.270  6.255   20.171  1.00 39.94  ? 53  UNK V N   1 
ATOM   7342 C CA  . UNK F 2 51  ? -1.284  4.862   20.584  1.00 40.34  ? 53  UNK V CA  1 
ATOM   7343 C C   . UNK F 2 51  ? -1.459  3.969   19.363  1.00 39.51  ? 53  UNK V C   1 
ATOM   7344 O O   . UNK F 2 51  ? -2.532  3.935   18.756  1.00 37.41  ? 53  UNK V O   1 
ATOM   7345 C CB  . UNK F 2 51  ? -2.403  4.605   21.595  1.00 35.36  ? 53  UNK V CB  1 
ATOM   7346 N N   . UNK F 2 52  ? -0.398  3.258   18.998  1.00 40.55  ? 54  UNK V N   1 
ATOM   7347 C CA  . UNK F 2 52  ? -0.463  2.311   17.894  1.00 42.83  ? 54  UNK V CA  1 
ATOM   7348 C C   . UNK F 2 52  ? -1.203  1.067   18.363  1.00 38.25  ? 54  UNK V C   1 
ATOM   7349 O O   . UNK F 2 52  ? -1.675  1.026   19.501  1.00 42.15  ? 54  UNK V O   1 
ATOM   7350 C CB  . UNK F 2 52  ? 0.938   1.951   17.396  1.00 39.86  ? 54  UNK V CB  1 
ATOM   7351 N N   . UNK F 2 53  ? -1.310  0.065   17.494  1.00 38.28  ? 55  UNK V N   1 
ATOM   7352 C CA  . UNK F 2 53  ? -1.930  -1.201  17.865  1.00 44.69  ? 55  UNK V CA  1 
ATOM   7353 C C   . UNK F 2 53  ? -1.231  -1.755  19.101  1.00 43.64  ? 55  UNK V C   1 
ATOM   7354 O O   . UNK F 2 53  ? -0.044  -1.494  19.298  1.00 44.97  ? 55  UNK V O   1 
ATOM   7355 C CB  . UNK F 2 53  ? -1.861  -2.205  16.712  1.00 35.87  ? 55  UNK V CB  1 
ATOM   7356 N N   . UNK F 2 54  ? -1.966  -2.489  19.930  1.00 39.40  ? 56  UNK V N   1 
ATOM   7357 C CA  . UNK F 2 54  ? -1.419  -3.033  21.170  1.00 47.13  ? 56  UNK V CA  1 
ATOM   7358 C C   . UNK F 2 54  ? -0.114  -3.787  20.918  1.00 39.14  ? 56  UNK V C   1 
ATOM   7359 O O   . UNK F 2 54  ? -0.012  -4.534  19.941  1.00 40.00  ? 56  UNK V O   1 
ATOM   7360 C CB  . UNK F 2 54  ? -2.441  -3.951  21.846  1.00 41.37  ? 56  UNK V CB  1 
ATOM   7361 N N   . UNK F 2 55  ? 0.862   -3.547  21.796  1.00 45.81  ? 57  UNK V N   1 
ATOM   7362 C CA  . UNK F 2 55  ? 2.224   -4.099  21.743  1.00 46.30  ? 57  UNK V CA  1 
ATOM   7363 C C   . UNK F 2 55  ? 3.130   -3.370  20.745  1.00 45.63  ? 57  UNK V C   1 
ATOM   7364 O O   . UNK F 2 55  ? 4.318   -3.685  20.658  1.00 46.05  ? 57  UNK V O   1 
ATOM   7365 C CB  . UNK F 2 55  ? 2.207   -5.602  21.429  1.00 55.68  ? 57  UNK V CB  1 
ATOM   7366 N N   . UNK F 2 56  ? 2.587   -2.403  20.011  1.00 42.51  ? 58  UNK V N   1 
ATOM   7367 C CA  . UNK F 2 56  ? 3.404   -1.578  19.120  1.00 44.58  ? 58  UNK V CA  1 
ATOM   7368 C C   . UNK F 2 56  ? 3.735   -0.259  19.815  1.00 43.90  ? 58  UNK V C   1 
ATOM   7369 O O   . UNK F 2 56  ? 4.379   0.620   19.236  1.00 50.30  ? 58  UNK V O   1 
ATOM   7370 C CB  . UNK F 2 56  ? 2.690   -1.322  17.791  1.00 44.16  ? 58  UNK V CB  1 
ATOM   7371 N N   . UNK F 2 57  ? 3.260   -0.143  21.055  1.00 39.31  ? 59  UNK V N   1 
ATOM   7372 C CA  . UNK F 2 57  ? 3.612   0.930   21.993  1.00 43.12  ? 59  UNK V CA  1 
ATOM   7373 C C   . UNK F 2 57  ? 3.002   2.290   21.667  1.00 42.98  ? 59  UNK V C   1 
ATOM   7374 O O   . UNK F 2 57  ? 2.287   2.469   20.678  1.00 43.56  ? 59  UNK V O   1 
ATOM   7375 C CB  . UNK F 2 57  ? 5.133   1.080   22.093  1.00 58.67  ? 59  UNK V CB  1 
ATOM   7376 N N   . UNK F 2 58  ? 3.305   3.251   22.535  1.00 39.86  ? 60  UNK V N   1 
ATOM   7377 C CA  . UNK F 2 58  ? 2.770   4.603   22.436  1.00 45.78  ? 60  UNK V CA  1 
ATOM   7378 C C   . UNK F 2 58  ? 3.896   5.629   22.383  1.00 41.63  ? 60  UNK V C   1 
ATOM   7379 O O   . UNK F 2 58  ? 4.966   5.433   22.962  1.00 35.71  ? 60  UNK V O   1 
ATOM   7380 C CB  . UNK F 2 58  ? 1.844   4.902   23.616  1.00 32.36  ? 60  UNK V CB  1 
ATOM   7381 N N   . UNK F 2 59  ? 3.641   6.725   21.679  1.00 33.01  ? 61  UNK V N   1 
ATOM   7382 C CA  . UNK F 2 59  ? 4.631   7.782   21.516  1.00 33.12  ? 61  UNK V CA  1 
ATOM   7383 C C   . UNK F 2 59  ? 4.023   9.130   21.888  1.00 34.28  ? 61  UNK V C   1 
ATOM   7384 O O   . UNK F 2 59  ? 2.812   9.319   21.768  1.00 35.08  ? 61  UNK V O   1 
ATOM   7385 C CB  . UNK F 2 59  ? 5.163   7.803   20.083  1.00 24.86  ? 61  UNK V CB  1 
ATOM   7386 N N   . UNK F 2 60  ? 4.855   10.062  22.343  1.00 35.55  ? 62  UNK V N   1 
ATOM   7387 C CA  . UNK F 2 60  ? 4.342   11.315  22.889  1.00 33.76  ? 62  UNK V CA  1 
ATOM   7388 C C   . UNK F 2 60  ? 5.110   12.538  22.402  1.00 39.04  ? 62  UNK V C   1 
ATOM   7389 O O   . UNK F 2 60  ? 6.287   12.457  22.046  1.00 35.41  ? 62  UNK V O   1 
ATOM   7390 C CB  . UNK F 2 60  ? 4.370   11.269  24.418  1.00 33.30  ? 62  UNK V CB  1 
ATOM   7391 N N   . UNK F 2 61  ? 4.425   13.676  22.387  1.00 39.99  ? 63  UNK V N   1 
ATOM   7392 C CA  . UNK F 2 61  ? 5.063   14.948  22.086  1.00 37.48  ? 63  UNK V CA  1 
ATOM   7393 C C   . UNK F 2 61  ? 5.975   15.325  23.247  1.00 38.67  ? 63  UNK V C   1 
ATOM   7394 O O   . UNK F 2 61  ? 5.792   14.844  24.366  1.00 42.65  ? 63  UNK V O   1 
ATOM   7395 C CB  . UNK F 2 61  ? 4.022   16.041  21.836  1.00 37.40  ? 63  UNK V CB  1 
ATOM   7396 N N   . ASP F 2 62  ? 6.950   16.186  22.979  1.00 38.86  ? 64  ASP V N   1 
ATOM   7397 C CA  . ASP F 2 62  ? 7.956   16.538  23.975  1.00 43.77  ? 64  ASP V CA  1 
ATOM   7398 C C   . ASP F 2 62  ? 7.356   17.310  25.149  1.00 48.15  ? 64  ASP V C   1 
ATOM   7399 O O   . ASP F 2 62  ? 7.771   17.133  26.294  1.00 45.15  ? 64  ASP V O   1 
ATOM   7400 C CB  . ASP F 2 62  ? 9.076   17.352  23.323  1.00 43.39  ? 64  ASP V CB  1 
ATOM   7401 C CG  . ASP F 2 62  ? 10.433  17.076  23.940  1.00 55.91  ? 64  ASP V CG  1 
ATOM   7402 O OD1 . ASP F 2 62  ? 10.583  17.267  25.164  1.00 60.18  ? 64  ASP V OD1 1 
ATOM   7403 O OD2 . ASP F 2 62  ? 11.345  16.655  23.199  1.00 63.28  ? 64  ASP V OD2 1 
ATOM   7404 N N   . SER F 2 63  ? 6.370   18.153  24.861  1.00 47.18  ? 65  SER V N   1 
ATOM   7405 C CA  . SER F 2 63  ? 5.770   19.009  25.882  1.00 52.67  ? 65  SER V CA  1 
ATOM   7406 C C   . SER F 2 63  ? 4.793   18.245  26.773  1.00 54.04  ? 65  SER V C   1 
ATOM   7407 O O   . SER F 2 63  ? 4.360   18.754  27.805  1.00 49.56  ? 65  SER V O   1 
ATOM   7408 C CB  . SER F 2 63  ? 5.058   20.195  25.227  1.00 51.67  ? 65  SER V CB  1 
ATOM   7409 O OG  . SER F 2 63  ? 4.046   19.755  24.338  1.00 54.35  ? 65  SER V OG  1 
ATOM   7410 N N   . UNK F 2 64  ? 4.448   17.027  26.371  1.00 47.78  ? 66  UNK V N   1 
ATOM   7411 C CA  . UNK F 2 64  ? 3.471   16.232  27.107  1.00 49.78  ? 66  UNK V CA  1 
ATOM   7412 C C   . UNK F 2 64  ? 4.113   14.983  27.702  1.00 50.86  ? 66  UNK V C   1 
ATOM   7413 O O   . UNK F 2 64  ? 3.471   14.247  28.452  1.00 49.35  ? 66  UNK V O   1 
ATOM   7414 C CB  . UNK F 2 64  ? 2.306   15.842  26.197  1.00 42.50  ? 66  UNK V CB  1 
ATOM   7415 N N   . UNK F 2 65  ? 5.380   14.759  27.365  1.00 42.93  ? 67  UNK V N   1 
ATOM   7416 C CA  . UNK F 2 65  ? 6.116   13.580  27.813  1.00 46.14  ? 67  UNK V CA  1 
ATOM   7417 C C   . UNK F 2 65  ? 6.144   13.449  29.333  1.00 46.14  ? 67  UNK V C   1 
ATOM   7418 O O   . UNK F 2 65  ? 6.664   14.318  30.035  1.00 45.89  ? 67  UNK V O   1 
ATOM   7419 C CB  . UNK F 2 65  ? 7.547   13.614  27.273  1.00 41.87  ? 67  UNK V CB  1 
ATOM   7420 N N   . GLY F 2 66  ? 5.575   12.358  29.835  1.00 46.93  ? 68  GLY V N   1 
ATOM   7421 C CA  . GLY F 2 66  ? 5.570   12.090  31.261  1.00 46.48  ? 68  GLY V CA  1 
ATOM   7422 C C   . GLY F 2 66  ? 4.345   12.588  32.001  1.00 51.08  ? 68  GLY V C   1 
ATOM   7423 O O   . GLY F 2 66  ? 4.019   12.093  33.081  1.00 51.23  ? 68  GLY V O   1 
ATOM   7424 N N   . ARG F 2 67  ? 3.657   13.566  31.417  1.00 51.16  ? 69  ARG V N   1 
ATOM   7425 C CA  . ARG F 2 67  ? 2.460   14.128  32.028  1.00 46.32  ? 69  ARG V CA  1 
ATOM   7426 C C   . ARG F 2 67  ? 1.176   13.562  31.445  1.00 55.19  ? 69  ARG V C   1 
ATOM   7427 O O   . ARG F 2 67  ? 0.179   13.450  32.165  1.00 54.17  ? 69  ARG V O   1 
ATOM   7428 C CB  . ARG F 2 67  ? 2.452   15.654  31.882  1.00 49.28  ? 69  ARG V CB  1 
ATOM   7429 C CG  . ARG F 2 67  ? 3.655   16.339  32.512  1.00 52.84  ? 69  ARG V CG  1 
ATOM   7430 C CD  . ARG F 2 67  ? 3.450   17.841  32.655  1.00 52.58  ? 69  ARG V CD  1 
ATOM   7431 N NE  . ARG F 2 67  ? 3.278   18.513  31.372  1.00 52.48  ? 69  ARG V NE  1 
ATOM   7432 C CZ  . ARG F 2 67  ? 2.125   18.993  30.927  1.00 52.06  ? 69  ARG V CZ  1 
ATOM   7433 N NH1 . ARG F 2 67  ? 1.013   18.888  31.636  1.00 59.45  ? 69  ARG V NH1 1 
ATOM   7434 N NH2 . ARG F 2 67  ? 2.086   19.595  29.742  1.00 53.19  ? 69  ARG V NH2 1 
ATOM   7435 N N   . PHE F 2 68  ? 1.174   13.201  30.166  1.00 55.55  ? 70  PHE V N   1 
ATOM   7436 C CA  . PHE F 2 68  ? 0.011   12.625  29.512  1.00 46.60  ? 70  PHE V CA  1 
ATOM   7437 C C   . PHE F 2 68  ? 0.253   11.141  29.266  1.00 47.01  ? 70  PHE V C   1 
ATOM   7438 O O   . PHE F 2 68  ? 1.396   10.695  29.130  1.00 47.23  ? 70  PHE V O   1 
ATOM   7439 C CB  . PHE F 2 68  ? -0.299  13.323  28.180  1.00 54.37  ? 70  PHE V CB  1 
ATOM   7440 C CG  . PHE F 2 68  ? -0.853  14.718  28.326  1.00 54.89  ? 70  PHE V CG  1 
ATOM   7441 C CD1 . PHE F 2 68  ? -0.872  15.361  29.553  1.00 53.16  ? 70  PHE V CD1 1 
ATOM   7442 C CD2 . PHE F 2 68  ? -1.364  15.382  27.223  1.00 52.55  ? 70  PHE V CD2 1 
ATOM   7443 C CE1 . PHE F 2 68  ? -1.381  16.640  29.675  1.00 56.29  ? 70  PHE V CE1 1 
ATOM   7444 C CE2 . PHE F 2 68  ? -1.877  16.660  27.339  1.00 53.20  ? 70  PHE V CE2 1 
ATOM   7445 C CZ  . PHE F 2 68  ? -1.885  17.290  28.567  1.00 54.61  ? 70  PHE V CZ  1 
ATOM   7446 N N   . THR F 2 69  ? -0.833  10.378  29.213  1.00 42.75  ? 71  THR V N   1 
ATOM   7447 C CA  . THR F 2 69  ? -0.736  8.947   28.949  1.00 45.61  ? 71  THR V CA  1 
ATOM   7448 C C   . THR F 2 69  ? -1.857  8.475   28.032  1.00 46.28  ? 71  THR V C   1 
ATOM   7449 O O   . THR F 2 69  ? -3.022  8.434   28.428  1.00 45.26  ? 71  THR V O   1 
ATOM   7450 C CB  . THR F 2 69  ? -0.773  8.124   30.249  1.00 49.46  ? 71  THR V CB  1 
ATOM   7451 O OG1 . THR F 2 69  ? 0.362   8.453   31.060  1.00 48.60  ? 71  THR V OG1 1 
ATOM   7452 C CG2 . THR F 2 69  ? -0.749  6.635   29.936  1.00 43.69  ? 71  THR V CG2 1 
ATOM   7453 N N   . UNK F 2 70  ? -1.496  8.122   26.803  1.00 47.33  ? 72  UNK V N   1 
ATOM   7454 C CA  . UNK F 2 70  ? -2.461  7.600   25.847  1.00 48.11  ? 72  UNK V CA  1 
ATOM   7455 C C   . UNK F 2 70  ? -2.616  6.098   26.042  1.00 45.84  ? 72  UNK V C   1 
ATOM   7456 O O   . UNK F 2 70  ? -1.649  5.402   26.354  1.00 49.17  ? 72  UNK V O   1 
ATOM   7457 C CB  . UNK F 2 70  ? -2.030  7.913   24.413  1.00 41.70  ? 72  UNK V CB  1 
ATOM   7458 N N   . SER F 2 71  ? -3.835  5.603   25.865  1.00 49.79  ? 73  SER V N   1 
ATOM   7459 C CA  . SER F 2 71  ? -4.106  4.178   26.005  1.00 47.05  ? 73  SER V CA  1 
ATOM   7460 C C   . SER F 2 71  ? -5.302  3.776   25.154  1.00 48.63  ? 73  SER V C   1 
ATOM   7461 O O   . SER F 2 71  ? -6.060  4.628   24.689  1.00 55.73  ? 73  SER V O   1 
ATOM   7462 C CB  . SER F 2 71  ? -4.353  3.818   27.470  1.00 47.05  ? 73  SER V CB  1 
ATOM   7463 O OG  . SER F 2 71  ? -5.367  4.634   28.031  1.00 45.37  ? 73  SER V OG  1 
ATOM   7464 N N   . UNK F 2 72  ? -5.470  2.473   24.953  1.00 47.01  ? 74  UNK V N   1 
ATOM   7465 C CA  . UNK F 2 72  ? -6.531  1.975   24.088  1.00 42.85  ? 74  UNK V CA  1 
ATOM   7466 C C   . UNK F 2 72  ? -7.345  0.869   24.753  1.00 50.43  ? 74  UNK V C   1 
ATOM   7467 O O   . UNK F 2 72  ? -6.864  0.162   25.639  1.00 49.74  ? 74  UNK V O   1 
ATOM   7468 C CB  . UNK F 2 72  ? -5.947  1.465   22.768  1.00 43.65  ? 74  UNK V CB  1 
ATOM   7469 N N   . ASP F 2 73  ? -8.592  0.738   24.314  1.00 50.96  ? 75  ASP V N   1 
ATOM   7470 C CA  . ASP F 2 73  ? -9.461  -0.352  24.735  1.00 51.76  ? 75  ASP V CA  1 
ATOM   7471 C C   . ASP F 2 73  ? -10.232 -0.839  23.512  1.00 53.52  ? 75  ASP V C   1 
ATOM   7472 O O   . ASP F 2 73  ? -11.354 -0.398  23.263  1.00 55.66  ? 75  ASP V O   1 
ATOM   7473 C CB  . ASP F 2 73  ? -10.416 0.102   25.844  1.00 48.65  ? 75  ASP V CB  1 
ATOM   7474 C CG  . ASP F 2 73  ? -11.159 -1.057  26.496  1.00 58.94  ? 75  ASP V CG  1 
ATOM   7475 O OD1 . ASP F 2 73  ? -11.296 -2.127  25.869  1.00 61.37  ? 75  ASP V OD1 1 
ATOM   7476 O OD2 . ASP F 2 73  ? -11.610 -0.893  27.649  1.00 60.19  ? 75  ASP V OD2 1 
ATOM   7477 N N   . UNK F 2 74  ? -9.618  -1.745  22.756  1.00 53.64  ? 76  UNK V N   1 
ATOM   7478 C CA  . UNK F 2 74  ? -10.178 -2.231  21.497  1.00 48.88  ? 76  UNK V CA  1 
ATOM   7479 C C   . UNK F 2 74  ? -11.572 -2.828  21.667  1.00 55.12  ? 76  UNK V C   1 
ATOM   7480 O O   . UNK F 2 74  ? -12.397 -2.753  20.754  1.00 58.95  ? 76  UNK V O   1 
ATOM   7481 C CB  . UNK F 2 74  ? -9.246  -3.271  20.872  1.00 50.19  ? 76  UNK V CB  1 
ATOM   7482 N N   . UNK F 2 75  ? -11.829 -3.411  22.834  1.00 53.99  ? 77  UNK V N   1 
ATOM   7483 C CA  . UNK F 2 75  ? -13.127 -4.007  23.133  1.00 55.79  ? 77  UNK V CA  1 
ATOM   7484 C C   . UNK F 2 75  ? -14.246 -2.973  23.058  1.00 54.44  ? 77  UNK V C   1 
ATOM   7485 O O   . UNK F 2 75  ? -15.288 -3.218  22.448  1.00 51.90  ? 77  UNK V O   1 
ATOM   7486 C CB  . UNK F 2 75  ? -13.109 -4.659  24.517  1.00 48.86  ? 77  UNK V CB  1 
ATOM   7487 N N   . UNK F 2 76  ? -14.024 -1.817  23.675  1.00 52.75  ? 78  UNK V N   1 
ATOM   7488 C CA  . UNK F 2 76  ? -15.010 -0.741  23.657  1.00 50.49  ? 78  UNK V CA  1 
ATOM   7489 C C   . UNK F 2 76  ? -14.778 0.179   22.464  1.00 56.09  ? 78  UNK V C   1 
ATOM   7490 O O   . UNK F 2 76  ? -15.440 1.211   22.335  1.00 56.35  ? 78  UNK V O   1 
ATOM   7491 C CB  . UNK F 2 76  ? -14.960 0.057   24.962  1.00 55.86  ? 78  UNK V CB  1 
ATOM   7492 N N   . UNK F 2 77  ? -13.838 -0.212  21.602  1.00 56.91  ? 79  UNK V N   1 
ATOM   7493 C CA  . UNK F 2 77  ? -13.464 0.560   20.416  1.00 50.68  ? 79  UNK V CA  1 
ATOM   7494 C C   . UNK F 2 77  ? -13.243 2.033   20.742  1.00 49.11  ? 79  UNK V C   1 
ATOM   7495 O O   . UNK F 2 77  ? -13.742 2.917   20.044  1.00 52.36  ? 79  UNK V O   1 
ATOM   7496 C CB  . UNK F 2 77  ? -14.530 0.418   19.327  1.00 58.16  ? 79  UNK V CB  1 
ATOM   7497 N N   . UNK F 2 78  ? -12.498 2.288   21.813  1.00 54.64  ? 80  UNK V N   1 
ATOM   7498 C CA  . UNK F 2 78  ? -12.281 3.650   22.279  1.00 46.08  ? 80  UNK V CA  1 
ATOM   7499 C C   . UNK F 2 78  ? -10.837 3.866   22.716  1.00 48.86  ? 80  UNK V C   1 
ATOM   7500 O O   . UNK F 2 78  ? -10.141 2.926   23.102  1.00 53.44  ? 80  UNK V O   1 
ATOM   7501 C CB  . UNK F 2 78  ? -13.230 3.978   23.433  1.00 51.60  ? 80  UNK V CB  1 
ATOM   7502 N N   . UNK F 2 79  ? -10.394 5.117   22.647  1.00 44.92  ? 81  UNK V N   1 
ATOM   7503 C CA  . UNK F 2 79  ? -9.062  5.489   23.108  1.00 43.51  ? 81  UNK V CA  1 
ATOM   7504 C C   . UNK F 2 79  ? -9.170  6.534   24.213  1.00 49.66  ? 81  UNK V C   1 
ATOM   7505 O O   . UNK F 2 79  ? -10.172 7.245   24.303  1.00 52.75  ? 81  UNK V O   1 
ATOM   7506 C CB  . UNK F 2 79  ? -8.217  6.018   21.948  1.00 50.40  ? 81  UNK V CB  1 
ATOM   7507 N N   . UNK F 2 80  ? -8.141  6.623   25.050  1.00 43.23  ? 82  UNK V N   1 
ATOM   7508 C CA  . UNK F 2 80  ? -8.160  7.545   26.181  1.00 46.68  ? 82  UNK V CA  1 
ATOM   7509 C C   . UNK F 2 80  ? -6.892  8.389   26.254  1.00 47.23  ? 82  UNK V C   1 
ATOM   7510 O O   . UNK F 2 80  ? -5.814  7.959   25.837  1.00 51.03  ? 82  UNK V O   1 
ATOM   7511 C CB  . UNK F 2 80  ? -8.347  6.774   27.489  1.00 36.88  ? 82  UNK V CB  1 
ATOM   7512 N N   . LEU F 2 81  ? -7.033  9.598   26.787  1.00 44.58  ? 83  LEU V N   1 
ATOM   7513 C CA  . LEU F 2 81  ? -5.895  10.478  27.022  1.00 46.88  ? 83  LEU V CA  1 
ATOM   7514 C C   . LEU F 2 81  ? -5.899  10.970  28.464  1.00 50.83  ? 83  LEU V C   1 
ATOM   7515 O O   . LEU F 2 81  ? -6.573  11.945  28.798  1.00 54.09  ? 83  LEU V O   1 
ATOM   7516 C CB  . LEU F 2 81  ? -5.913  11.668  26.060  1.00 43.55  ? 83  LEU V CB  1 
ATOM   7517 C CG  . LEU F 2 81  ? -4.739  12.640  26.208  1.00 42.76  ? 83  LEU V CG  1 
ATOM   7518 C CD1 . LEU F 2 81  ? -3.449  12.010  25.705  1.00 41.88  ? 83  LEU V CD1 1 
ATOM   7519 C CD2 . LEU F 2 81  ? -5.020  13.953  25.491  1.00 42.24  ? 83  LEU V CD2 1 
ATOM   7520 N N   . GLN F 2 82  ? -5.146  10.286  29.318  1.00 54.40  ? 84  GLN V N   1 
ATOM   7521 C CA  . GLN F 2 82  ? -5.023  10.685  30.712  1.00 49.87  ? 84  GLN V CA  1 
ATOM   7522 C C   . GLN F 2 82  ? -4.101  11.892  30.838  1.00 51.85  ? 84  GLN V C   1 
ATOM   7523 O O   . GLN F 2 82  ? -2.914  11.810  30.526  1.00 52.73  ? 84  GLN V O   1 
ATOM   7524 C CB  . GLN F 2 82  ? -4.498  9.526   31.560  1.00 48.21  ? 84  GLN V CB  1 
ATOM   7525 C CG  . GLN F 2 82  ? -4.388  9.844   33.040  1.00 58.62  ? 84  GLN V CG  1 
ATOM   7526 C CD  . GLN F 2 82  ? -5.745  9.970   33.703  1.00 55.11  ? 84  GLN V CD  1 
ATOM   7527 O OE1 . GLN F 2 82  ? -6.646  9.169   33.456  1.00 56.62  ? 84  GLN V OE1 1 
ATOM   7528 N NE2 . GLN F 2 82  ? -5.899  10.982  34.551  1.00 57.97  ? 84  GLN V NE2 1 
ATOM   7529 N N   . UNK F 2 83  ? -4.652  13.010  31.296  1.00 57.55  ? 85  UNK V N   1 
ATOM   7530 C CA  . UNK F 2 83  ? -3.885  14.243  31.421  1.00 58.63  ? 85  UNK V CA  1 
ATOM   7531 C C   . UNK F 2 83  ? -3.695  14.626  32.885  1.00 62.36  ? 85  UNK V C   1 
ATOM   7532 O O   . UNK F 2 83  ? -4.666  14.872  33.601  1.00 64.40  ? 85  UNK V O   1 
ATOM   7533 C CB  . UNK F 2 83  ? -4.575  15.380  30.664  1.00 54.41  ? 85  UNK V CB  1 
ATOM   7534 N N   . UNK F 2 84  ? -2.441  14.672  33.324  1.00 55.61  ? 86  UNK V N   1 
ATOM   7535 C CA  . UNK F 2 84  ? -2.123  15.019  34.704  1.00 59.03  ? 86  UNK V CA  1 
ATOM   7536 C C   . UNK F 2 84  ? -1.200  16.233  34.761  1.00 62.29  ? 86  UNK V C   1 
ATOM   7537 O O   . UNK F 2 84  ? -0.479  16.513  33.801  1.00 68.83  ? 86  UNK V O   1 
ATOM   7538 C CB  . UNK F 2 84  ? -1.476  13.832  35.421  1.00 53.69  ? 86  UNK V CB  1 
ATOM   7539 N N   . UNK F 2 85  ? -1.234  16.939  35.890  1.00 60.60  ? 87  UNK V N   1 
ATOM   7540 C CA  . UNK F 2 85  ? -0.416  18.133  36.108  1.00 59.82  ? 87  UNK V CA  1 
ATOM   7541 C C   . UNK F 2 85  ? -0.610  19.157  34.993  1.00 61.11  ? 87  UNK V C   1 
ATOM   7542 O O   . UNK F 2 85  ? 0.359   19.619  34.389  1.00 62.50  ? 87  UNK V O   1 
ATOM   7543 C CB  . UNK F 2 85  ? 1.064   17.756  36.225  1.00 57.84  ? 87  UNK V CB  1 
ATOM   7544 N N   . LEU F 2 86  ? -1.865  19.504  34.725  1.00 64.68  ? 88  LEU V N   1 
ATOM   7545 C CA  . LEU F 2 86  ? -2.194  20.436  33.651  1.00 66.01  ? 88  LEU V CA  1 
ATOM   7546 C C   . LEU F 2 86  ? -1.661  21.840  33.902  1.00 64.46  ? 88  LEU V C   1 
ATOM   7547 O O   . LEU F 2 86  ? -1.857  22.412  34.975  1.00 69.17  ? 88  LEU V O   1 
ATOM   7548 C CB  . LEU F 2 86  ? -3.710  20.508  33.433  1.00 64.39  ? 88  LEU V CB  1 
ATOM   7549 C CG  . LEU F 2 86  ? -4.457  19.302  32.853  1.00 60.32  ? 88  LEU V CG  1 
ATOM   7550 C CD1 . LEU F 2 86  ? -3.747  18.782  31.612  1.00 66.74  ? 88  LEU V CD1 1 
ATOM   7551 C CD2 . LEU F 2 86  ? -4.648  18.198  33.875  1.00 64.32  ? 88  LEU V CD2 1 
ATOM   7552 N N   . UNK F 2 87  ? -0.984  22.385  32.898  1.00 62.88  ? 89  UNK V N   1 
ATOM   7553 C CA  . UNK F 2 87  ? -0.564  23.778  32.920  1.00 61.09  ? 89  UNK V CA  1 
ATOM   7554 C C   . UNK F 2 87  ? -1.574  24.587  32.118  1.00 69.34  ? 89  UNK V C   1 
ATOM   7555 O O   . UNK F 2 87  ? -2.414  24.013  31.423  1.00 65.85  ? 89  UNK V O   1 
ATOM   7556 C CB  . UNK F 2 87  ? 0.845   23.941  32.346  1.00 56.28  ? 89  UNK V CB  1 
ATOM   7557 N N   . UNK F 2 88  ? -1.497  25.910  32.213  1.00 68.96  ? 90  UNK V N   1 
ATOM   7558 C CA  . UNK F 2 88  ? -2.422  26.777  31.493  1.00 62.66  ? 90  UNK V CA  1 
ATOM   7559 C C   . UNK F 2 88  ? -2.193  26.697  29.986  1.00 66.35  ? 90  UNK V C   1 
ATOM   7560 O O   . UNK F 2 88  ? -3.094  26.982  29.195  1.00 64.36  ? 90  UNK V O   1 
ATOM   7561 C CB  . UNK F 2 88  ? -2.282  28.224  31.970  1.00 63.79  ? 90  UNK V CB  1 
ATOM   7562 N N   . UNK F 2 89  ? -0.985  26.299  29.595  1.00 64.46  ? 91  UNK V N   1 
ATOM   7563 C CA  . UNK F 2 89  ? -0.627  26.190  28.184  1.00 67.08  ? 91  UNK V CA  1 
ATOM   7564 C C   . UNK F 2 89  ? -1.294  24.990  27.518  1.00 60.94  ? 91  UNK V C   1 
ATOM   7565 O O   . UNK F 2 89  ? -1.283  24.867  26.292  1.00 64.28  ? 91  UNK V O   1 
ATOM   7566 C CB  . UNK F 2 89  ? 0.893   26.092  28.028  1.00 61.48  ? 91  UNK V CB  1 
ATOM   7567 N N   . ASP F 2 90  ? -1.876  24.110  28.326  1.00 60.34  ? 92  ASP V N   1 
ATOM   7568 C CA  . ASP F 2 90  ? -2.531  22.914  27.808  1.00 59.73  ? 92  ASP V CA  1 
ATOM   7569 C C   . ASP F 2 90  ? -3.976  23.188  27.400  1.00 62.67  ? 92  ASP V C   1 
ATOM   7570 O O   . ASP F 2 90  ? -4.698  22.277  26.997  1.00 58.67  ? 92  ASP V O   1 
ATOM   7571 C CB  . ASP F 2 90  ? -2.484  21.790  28.844  1.00 59.11  ? 92  ASP V CB  1 
ATOM   7572 C CG  . ASP F 2 90  ? -1.071  21.341  29.153  1.00 64.66  ? 92  ASP V CG  1 
ATOM   7573 O OD1 . ASP F 2 90  ? -0.235  21.330  28.226  1.00 59.83  ? 92  ASP V OD1 1 
ATOM   7574 O OD2 . ASP F 2 90  ? -0.796  20.998  30.321  1.00 61.30  ? 92  ASP V OD2 1 
ATOM   7575 N N   . UNK F 2 91  ? -4.394  24.446  27.507  1.00 60.73  ? 93  UNK V N   1 
ATOM   7576 C CA  . UNK F 2 91  ? -5.751  24.833  27.139  1.00 62.50  ? 93  UNK V CA  1 
ATOM   7577 C C   . UNK F 2 91  ? -5.893  24.901  25.622  1.00 57.49  ? 93  UNK V C   1 
ATOM   7578 O O   . UNK F 2 91  ? -5.249  25.729  24.974  1.00 57.94  ? 93  UNK V O   1 
ATOM   7579 C CB  . UNK F 2 91  ? -6.117  26.179  27.767  1.00 55.75  ? 93  UNK V CB  1 
ATOM   7580 N N   . ALA F 2 92  ? -6.737  24.032  25.070  1.00 51.37  ? 94  ALA V N   1 
ATOM   7581 C CA  . ALA F 2 92  ? -6.950  23.959  23.625  1.00 53.98  ? 94  ALA V CA  1 
ATOM   7582 C C   . ALA F 2 92  ? -8.125  23.045  23.280  1.00 51.82  ? 94  ALA V C   1 
ATOM   7583 O O   . ALA F 2 92  ? -8.748  22.455  24.164  1.00 55.86  ? 94  ALA V O   1 
ATOM   7584 C CB  . ALA F 2 92  ? -5.685  23.469  22.928  1.00 57.15  ? 94  ALA V CB  1 
ATOM   7585 N N   . UNK F 2 93  ? -8.424  22.928  21.990  1.00 45.44  ? 95  UNK V N   1 
ATOM   7586 C CA  . UNK F 2 93  ? -9.368  21.924  21.520  1.00 52.06  ? 95  UNK V CA  1 
ATOM   7587 C C   . UNK F 2 93  ? -8.593  20.671  21.131  1.00 52.35  ? 95  UNK V C   1 
ATOM   7588 O O   . UNK F 2 93  ? -7.691  20.725  20.298  1.00 50.06  ? 95  UNK V O   1 
ATOM   7589 C CB  . UNK F 2 93  ? -10.183 22.446  20.337  1.00 54.78  ? 95  UNK V CB  1 
ATOM   7590 N N   . TYR F 2 94  ? -8.942  19.546  21.743  1.00 51.16  ? 96  TYR V N   1 
ATOM   7591 C CA  . TYR F 2 94  ? -8.248  18.291  21.500  1.00 49.46  ? 96  TYR V CA  1 
ATOM   7592 C C   . TYR F 2 94  ? -9.032  17.399  20.542  1.00 47.84  ? 96  TYR V C   1 
ATOM   7593 O O   . TYR F 2 94  ? -10.190 17.055  20.794  1.00 52.38  ? 96  TYR V O   1 
ATOM   7594 C CB  . TYR F 2 94  ? -7.987  17.566  22.823  1.00 47.93  ? 96  TYR V CB  1 
ATOM   7595 C CG  . TYR F 2 94  ? -6.884  18.195  23.648  1.00 50.85  ? 96  TYR V CG  1 
ATOM   7596 C CD1 . TYR F 2 94  ? -7.068  19.427  24.263  1.00 49.47  ? 96  TYR V CD1 1 
ATOM   7597 C CD2 . TYR F 2 94  ? -5.661  17.559  23.810  1.00 49.61  ? 96  TYR V CD2 1 
ATOM   7598 C CE1 . TYR F 2 94  ? -6.064  20.010  25.013  1.00 56.19  ? 96  TYR V CE1 1 
ATOM   7599 C CE2 . TYR F 2 94  ? -4.651  18.132  24.560  1.00 49.41  ? 96  TYR V CE2 1 
ATOM   7600 C CZ  . TYR F 2 94  ? -4.858  19.359  25.160  1.00 50.53  ? 96  TYR V CZ  1 
ATOM   7601 O OH  . TYR F 2 94  ? -3.856  19.936  25.908  1.00 52.55  ? 96  TYR V OH  1 
ATOM   7602 N N   . TYR F 2 95  ? -8.389  17.052  19.431  1.00 47.42  ? 97  TYR V N   1 
ATOM   7603 C CA  . TYR F 2 95  ? -8.965  16.208  18.398  1.00 43.07  ? 97  TYR V CA  1 
ATOM   7604 C C   . TYR F 2 95  ? -8.322  14.828  18.432  1.00 47.68  ? 97  TYR V C   1 
ATOM   7605 O O   . TYR F 2 95  ? -7.159  14.671  18.817  1.00 50.25  ? 97  TYR V O   1 
ATOM   7606 C CB  . TYR F 2 95  ? -8.771  16.809  17.002  1.00 49.50  ? 97  TYR V CB  1 
ATOM   7607 C CG  . TYR F 2 95  ? -9.351  18.190  16.809  1.00 49.03  ? 97  TYR V CG  1 
ATOM   7608 C CD1 . TYR F 2 95  ? -8.621  19.324  17.140  1.00 47.26  ? 97  TYR V CD1 1 
ATOM   7609 C CD2 . TYR F 2 95  ? -10.622 18.360  16.277  1.00 50.06  ? 97  TYR V CD2 1 
ATOM   7610 C CE1 . TYR F 2 95  ? -9.145  20.588  16.957  1.00 52.61  ? 97  TYR V CE1 1 
ATOM   7611 C CE2 . TYR F 2 95  ? -11.155 19.620  16.090  1.00 50.47  ? 97  TYR V CE2 1 
ATOM   7612 C CZ  . TYR F 2 95  ? -10.412 20.731  16.432  1.00 53.18  ? 97  TYR V CZ  1 
ATOM   7613 O OH  . TYR F 2 95  ? -10.938 21.989  16.247  1.00 59.93  ? 97  TYR V OH  1 
ATOM   7614 N N   . CYS F 2 96  ? -9.097  13.829  18.028  1.00 44.68  ? 98  CYS V N   1 
ATOM   7615 C CA  . CYS F 2 96  ? -8.569  12.486  17.846  1.00 43.62  ? 98  CYS V CA  1 
ATOM   7616 C C   . CYS F 2 96  ? -8.702  12.102  16.379  1.00 44.36  ? 98  CYS V C   1 
ATOM   7617 O O   . CYS F 2 96  ? -9.716  12.385  15.742  1.00 50.53  ? 98  CYS V O   1 
ATOM   7618 C CB  . CYS F 2 96  ? -9.295  11.481  18.737  1.00 48.32  ? 98  CYS V CB  1 
ATOM   7619 S SG  . CYS F 2 96  ? -8.645  9.797   18.635  1.00 51.93  ? 98  CYS V SG  1 
ATOM   7620 N N   . UNK F 2 97  ? -7.668  11.463  15.847  1.00 46.80  ? 99  UNK V N   1 
ATOM   7621 C CA  . UNK F 2 97  ? -7.645  11.087  14.442  1.00 40.86  ? 99  UNK V CA  1 
ATOM   7622 C C   . UNK F 2 97  ? -7.208  9.640   14.281  1.00 44.68  ? 99  UNK V C   1 
ATOM   7623 O O   . UNK F 2 97  ? -6.448  9.101   15.093  1.00 46.09  ? 99  UNK V O   1 
ATOM   7624 C CB  . UNK F 2 97  ? -6.715  12.009  13.651  1.00 42.97  ? 99  UNK V CB  1 
ATOM   7625 N N   . UNK F 2 98  ? -7.700  9.007   13.222  1.00 35.13  ? 100 UNK V N   1 
ATOM   7626 C CA  . UNK F 2 98  ? -7.310  7.635   12.924  1.00 45.39  ? 100 UNK V CA  1 
ATOM   7627 C C   . UNK F 2 98  ? -6.246  7.611   11.835  1.00 43.24  ? 100 UNK V C   1 
ATOM   7628 O O   . UNK F 2 98  ? -6.393  8.259   10.799  1.00 37.51  ? 100 UNK V O   1 
ATOM   7629 C CB  . UNK F 2 98  ? -8.524  6.809   12.501  1.00 45.84  ? 100 UNK V CB  1 
ATOM   7630 N N   . UNK F 2 99  ? -5.169  6.874   12.079  1.00 41.06  ? 101 UNK V N   1 
ATOM   7631 C CA  . UNK F 2 99  ? -4.158  6.652   11.055  1.00 35.09  ? 101 UNK V CA  1 
ATOM   7632 C C   . UNK F 2 99  ? -4.593  5.493   10.167  1.00 40.14  ? 101 UNK V C   1 
ATOM   7633 O O   . UNK F 2 99  ? -4.549  4.335   10.583  1.00 39.82  ? 101 UNK V O   1 
ATOM   7634 C CB  . UNK F 2 99  ? -2.793  6.371   11.685  1.00 42.67  ? 101 UNK V CB  1 
ATOM   7635 N N   . UNK F 2 100 ? -5.013  5.809   8.945   1.00 35.38  ? 102 UNK V N   1 
ATOM   7636 C CA  . UNK F 2 100 ? -5.552  4.803   8.030   1.00 42.10  ? 102 UNK V CA  1 
ATOM   7637 C C   . UNK F 2 100 ? -4.469  3.874   7.489   1.00 36.14  ? 102 UNK V C   1 
ATOM   7638 O O   . UNK F 2 100 ? -4.775  2.831   6.908   1.00 40.11  ? 102 UNK V O   1 
ATOM   7639 C CB  . UNK F 2 100 ? -6.282  5.479   6.870   1.00 42.00  ? 102 UNK V CB  1 
ATOM   7640 N N   . UNK F 2 101 ? -3.211  4.254   7.682   1.00 34.34  ? 103 UNK V N   1 
ATOM   7641 C CA  . UNK F 2 101 ? -2.091  3.440   7.227   1.00 36.82  ? 103 UNK V CA  1 
ATOM   7642 C C   . UNK F 2 101 ? -1.668  2.451   8.307   1.00 39.79  ? 103 UNK V C   1 
ATOM   7643 O O   . UNK F 2 101 ? -1.252  2.847   9.397   1.00 33.80  ? 103 UNK V O   1 
ATOM   7644 C CB  . UNK F 2 101 ? -0.907  4.325   6.829   1.00 41.11  ? 103 UNK V CB  1 
ATOM   7645 N N   . UNK F 2 102 ? -1.774  1.163   7.997   1.00 38.28  ? 104 UNK V N   1 
ATOM   7646 C CA  . UNK F 2 102 ? -1.395  0.113   8.935   1.00 38.06  ? 104 UNK V CA  1 
ATOM   7647 C C   . UNK F 2 102 ? 0.112   0.113   9.167   1.00 37.20  ? 104 UNK V C   1 
ATOM   7648 O O   . UNK F 2 102 ? 0.594   -0.403  10.177  1.00 32.81  ? 104 UNK V O   1 
ATOM   7649 C CB  . UNK F 2 102 ? -1.852  -1.255  8.422   1.00 35.70  ? 104 UNK V CB  1 
ATOM   7650 N N   . UNK F 2 103 ? 0.851   0.701   8.229   1.00 30.56  ? 105 UNK V N   1 
ATOM   7651 C CA  . UNK F 2 103 ? 2.305   0.789   8.330   1.00 34.81  ? 105 UNK V CA  1 
ATOM   7652 C C   . UNK F 2 103 ? 2.729   2.032   9.112   1.00 30.29  ? 105 UNK V C   1 
ATOM   7653 O O   . UNK F 2 103 ? 3.918   2.356   9.173   1.00 36.49  ? 105 UNK V O   1 
ATOM   7654 C CB  . UNK F 2 103 ? 2.937   0.796   6.936   1.00 26.27  ? 105 UNK V CB  1 
ATOM   7655 N N   . UNK F 2 104 ? 1.745   2.720   9.687   1.00 29.22  ? 106 UNK V N   1 
ATOM   7656 C CA  . UNK F 2 104 ? 1.965   3.844   10.600  1.00 34.53  ? 106 UNK V CA  1 
ATOM   7657 C C   . UNK F 2 104 ? 2.653   5.045   9.952   1.00 34.05  ? 106 UNK V C   1 
ATOM   7658 O O   . UNK F 2 104 ? 3.399   5.765   10.617  1.00 36.09  ? 106 UNK V O   1 
ATOM   7659 C CB  . UNK F 2 104 ? 2.776   3.385   11.816  1.00 33.67  ? 106 UNK V CB  1 
ATOM   7660 N N   . UNK F 2 105 ? 2.394   5.267   8.668   1.00 27.91  ? 107 UNK V N   1 
ATOM   7661 C CA  . UNK F 2 105 ? 2.924   6.443   7.984   1.00 35.54  ? 107 UNK V CA  1 
ATOM   7662 C C   . UNK F 2 105 ? 2.114   7.675   8.380   1.00 41.35  ? 107 UNK V C   1 
ATOM   7663 O O   . UNK F 2 105 ? 2.595   8.800   8.232   1.00 36.40  ? 107 UNK V O   1 
ATOM   7664 C CB  . UNK F 2 105 ? 2.902   6.248   6.468   1.00 31.32  ? 107 UNK V CB  1 
ATOM   7665 N N   . UNK F 2 106 ? 0.898   7.423   8.873   1.00 46.38  ? 108 UNK V N   1 
ATOM   7666 C CA  . UNK F 2 106 ? -0.086  8.417   9.343   1.00 42.31  ? 108 UNK V CA  1 
ATOM   7667 C C   . UNK F 2 106 ? -0.930  9.070   8.261   1.00 41.66  ? 108 UNK V C   1 
ATOM   7668 O O   . UNK F 2 106 ? -0.930  10.294  8.127   1.00 42.00  ? 108 UNK V O   1 
ATOM   7669 C CB  . UNK F 2 106 ? 0.578   9.531   10.141  1.00 41.51  ? 108 UNK V CB  1 
ATOM   7670 N N   . UNK F 2 107 ? -1.674  8.266   7.517   1.00 44.05  ? 109 UNK V N   1 
ATOM   7671 C CA  . UNK F 2 107 ? -2.713  8.814   6.665   1.00 38.75  ? 109 UNK V CA  1 
ATOM   7672 C C   . UNK F 2 107 ? -3.907  9.186   7.542   1.00 40.93  ? 109 UNK V C   1 
ATOM   7673 O O   . UNK F 2 107 ? -4.854  8.410   7.669   1.00 37.49  ? 109 UNK V O   1 
ATOM   7674 C CB  . UNK F 2 107 ? -3.119  7.815   5.581   1.00 34.90  ? 109 UNK V CB  1 
ATOM   7675 N N   . UNK F 2 108 ? -3.846  10.361  8.164   1.00 34.40  ? 110 UNK V N   1 
ATOM   7676 C CA  . UNK F 2 108 ? -4.931  10.828  9.026   1.00 46.42  ? 110 UNK V CA  1 
ATOM   7677 C C   . UNK F 2 108 ? -6.106  11.303  8.179   1.00 44.03  ? 110 UNK V C   1 
ATOM   7678 O O   . UNK F 2 108 ? -6.252  12.497  7.915   1.00 47.93  ? 110 UNK V O   1 
ATOM   7679 C CB  . UNK F 2 108 ? -4.450  11.952  9.945   1.00 46.26  ? 110 UNK V CB  1 
ATOM   7680 N N   . UNK F 2 109 ? -6.944  10.361  7.758   1.00 44.32  ? 111 UNK V N   1 
ATOM   7681 C CA  . UNK F 2 109 ? -8.061  10.669  6.873   1.00 45.14  ? 111 UNK V CA  1 
ATOM   7682 C C   . UNK F 2 109 ? -9.340  10.979  7.647   1.00 46.04  ? 111 UNK V C   1 
ATOM   7683 O O   . UNK F 2 109 ? -10.174 11.759  7.185   1.00 49.17  ? 111 UNK V O   1 
ATOM   7684 C CB  . UNK F 2 109 ? -8.306  9.508   5.905   1.00 39.17  ? 111 UNK V CB  1 
ATOM   7685 N N   . UNK F 2 110 ? -9.489  10.371  8.820   1.00 46.81  ? 112 UNK V N   1 
ATOM   7686 C CA  . UNK F 2 110 ? -10.677 10.580  9.641   1.00 42.90  ? 112 UNK V CA  1 
ATOM   7687 C C   . UNK F 2 110 ? -10.339 11.267  10.962  1.00 45.54  ? 112 UNK V C   1 
ATOM   7688 O O   . UNK F 2 110 ? -9.462  10.823  11.715  1.00 47.16  ? 112 UNK V O   1 
ATOM   7689 C CB  . UNK F 2 110 ? -11.384 9.249   9.909   1.00 43.45  ? 112 UNK V CB  1 
ATOM   7690 N N   . TRP F 2 111 ? -11.049 12.361  11.230  1.00 44.61  ? 113 TRP V N   1 
ATOM   7691 C CA  . TRP F 2 111 ? -10.859 13.154  12.439  1.00 45.03  ? 113 TRP V CA  1 
ATOM   7692 C C   . TRP F 2 111 ? -12.142 13.228  13.261  1.00 44.20  ? 113 TRP V C   1 
ATOM   7693 O O   . TRP F 2 111 ? -13.209 12.816  12.806  1.00 53.66  ? 113 TRP V O   1 
ATOM   7694 C CB  . TRP F 2 111 ? -10.394 14.569  12.089  1.00 45.34  ? 113 TRP V CB  1 
ATOM   7695 C CG  . TRP F 2 111 ? -8.999  14.649  11.557  1.00 45.24  ? 113 TRP V CG  1 
ATOM   7696 C CD1 . TRP F 2 111 ? -8.589  14.385  10.284  1.00 40.06  ? 113 TRP V CD1 1 
ATOM   7697 C CD2 . TRP F 2 111 ? -7.828  15.036  12.284  1.00 45.89  ? 113 TRP V CD2 1 
ATOM   7698 N NE1 . TRP F 2 111 ? -7.233  14.577  10.174  1.00 45.51  ? 113 TRP V NE1 1 
ATOM   7699 C CE2 . TRP F 2 111 ? -6.742  14.978  11.389  1.00 46.05  ? 113 TRP V CE2 1 
ATOM   7700 C CE3 . TRP F 2 111 ? -7.592  15.423  13.606  1.00 47.52  ? 113 TRP V CE3 1 
ATOM   7701 C CZ2 . TRP F 2 111 ? -5.440  15.292  11.774  1.00 44.77  ? 113 TRP V CZ2 1 
ATOM   7702 C CZ3 . TRP F 2 111 ? -6.300  15.734  13.987  1.00 47.52  ? 113 TRP V CZ3 1 
ATOM   7703 C CH2 . TRP F 2 111 ? -5.240  15.667  13.075  1.00 42.97  ? 113 TRP V CH2 1 
ATOM   7704 N N   . GLY F 2 112 ? -12.029 13.761  14.474  1.00 45.07  ? 114 GLY V N   1 
ATOM   7705 C CA  . GLY F 2 112 ? -13.181 13.951  15.336  1.00 45.34  ? 114 GLY V CA  1 
ATOM   7706 C C   . GLY F 2 112 ? -13.616 15.401  15.420  1.00 46.51  ? 114 GLY V C   1 
ATOM   7707 O O   . GLY F 2 112 ? -13.033 16.271  14.773  1.00 52.72  ? 114 GLY V O   1 
ATOM   7708 N N   . UNK F 2 113 ? -14.644 15.663  16.221  1.00 41.85  ? 115 UNK V N   1 
ATOM   7709 C CA  . UNK F 2 113 ? -15.153 17.019  16.398  1.00 46.39  ? 115 UNK V CA  1 
ATOM   7710 C C   . UNK F 2 113 ? -14.318 17.776  17.425  1.00 48.03  ? 115 UNK V C   1 
ATOM   7711 O O   . UNK F 2 113 ? -14.293 19.008  17.436  1.00 52.57  ? 115 UNK V O   1 
ATOM   7712 C CB  . UNK F 2 113 ? -16.622 16.991  16.824  1.00 42.77  ? 115 UNK V CB  1 
ATOM   7713 N N   . GLY F 2 114 ? -13.637 17.028  18.287  1.00 48.65  ? 116 GLY V N   1 
ATOM   7714 C CA  . GLY F 2 114 ? -12.773 17.609  19.298  1.00 45.34  ? 116 GLY V CA  1 
ATOM   7715 C C   . GLY F 2 114 ? -13.491 17.943  20.590  1.00 51.98  ? 116 GLY V C   1 
ATOM   7716 O O   . GLY F 2 114 ? -14.721 17.930  20.646  1.00 51.47  ? 116 GLY V O   1 
ATOM   7717 N N   . THR F 2 115 ? -12.726 18.237  21.638  1.00 53.44  ? 117 THR V N   1 
ATOM   7718 C CA  . THR F 2 115 ? -13.315 18.653  22.908  1.00 50.85  ? 117 THR V CA  1 
ATOM   7719 C C   . THR F 2 115 ? -12.486 19.780  23.527  1.00 57.30  ? 117 THR V C   1 
ATOM   7720 O O   . THR F 2 115 ? -11.267 19.810  23.391  1.00 55.02  ? 117 THR V O   1 
ATOM   7721 C CB  . THR F 2 115 ? -13.444 17.463  23.895  1.00 57.07  ? 117 THR V CB  1 
ATOM   7722 O OG1 . THR F 2 115 ? -14.383 17.790  24.926  1.00 53.29  ? 117 THR V OG1 1 
ATOM   7723 C CG2 . THR F 2 115 ? -12.102 17.114  24.529  1.00 54.82  ? 117 THR V CG2 1 
ATOM   7724 N N   . UNK F 2 116 ? -13.152 20.721  24.185  1.00 55.93  ? 118 UNK V N   1 
ATOM   7725 C CA  . UNK F 2 116 ? -12.462 21.880  24.742  1.00 55.81  ? 118 UNK V CA  1 
ATOM   7726 C C   . UNK F 2 116 ? -11.887 21.572  26.119  1.00 60.09  ? 118 UNK V C   1 
ATOM   7727 O O   . UNK F 2 116 ? -12.575 21.014  26.975  1.00 60.55  ? 118 UNK V O   1 
ATOM   7728 C CB  . UNK F 2 116 ? -13.407 23.081  24.823  1.00 57.93  ? 118 UNK V CB  1 
ATOM   7729 N N   . VAL F 2 117 ? -10.624 21.931  26.331  1.00 58.56  ? 119 VAL V N   1 
ATOM   7730 C CA  . VAL F 2 117 ? -9.996  21.788  27.636  1.00 54.13  ? 119 VAL V CA  1 
ATOM   7731 C C   . VAL F 2 117 ? -9.404  23.138  28.017  1.00 62.99  ? 119 VAL V C   1 
ATOM   7732 O O   . VAL F 2 117 ? -8.504  23.635  27.337  1.00 62.71  ? 119 VAL V O   1 
ATOM   7733 C CB  . VAL F 2 117 ? -8.913  20.691  27.629  1.00 55.00  ? 119 VAL V CB  1 
ATOM   7734 C CG1 . VAL F 2 117 ? -8.332  20.502  29.022  1.00 55.00  ? 119 VAL V CG1 1 
ATOM   7735 C CG2 . VAL F 2 117 ? -9.469  19.382  27.087  1.00 54.31  ? 119 VAL V CG2 1 
ATOM   7736 N N   . THR F 2 118 ? -9.900  23.741  29.096  1.00 61.18  ? 120 THR V N   1 
ATOM   7737 C CA  . THR F 2 118 ? -9.419  25.036  29.554  1.00 66.91  ? 120 THR V CA  1 
ATOM   7738 C C   . THR F 2 118 ? -8.863  24.898  30.962  1.00 68.39  ? 120 THR V C   1 
ATOM   7739 O O   . THR F 2 118 ? -9.546  24.386  31.853  1.00 66.65  ? 120 THR V O   1 
ATOM   7740 C CB  . THR F 2 118 ? -10.537 26.082  29.527  1.00 67.19  ? 120 THR V CB  1 
ATOM   7741 O OG1 . THR F 2 118 ? -11.775 25.476  29.918  1.00 70.72  ? 120 THR V OG1 1 
ATOM   7742 C CG2 . THR F 2 118 ? -10.681 26.672  28.131  1.00 65.44  ? 120 THR V CG2 1 
ATOM   7743 N N   . VAL F 2 119 ? -7.634  25.363  31.156  1.00 64.44  ? 121 VAL V N   1 
ATOM   7744 C CA  . VAL F 2 119 ? -6.954  25.249  32.440  1.00 67.90  ? 121 VAL V CA  1 
ATOM   7745 C C   . VAL F 2 119 ? -6.686  26.633  33.019  1.00 71.81  ? 121 VAL V C   1 
ATOM   7746 O O   . VAL F 2 119 ? -5.879  27.392  32.486  1.00 71.63  ? 121 VAL V O   1 
ATOM   7747 C CB  . VAL F 2 119 ? -5.642  24.452  32.307  1.00 67.65  ? 121 VAL V CB  1 
ATOM   7748 C CG1 . VAL F 2 119 ? -4.870  24.477  33.619  1.00 65.52  ? 121 VAL V CG1 1 
ATOM   7749 C CG2 . VAL F 2 119 ? -5.934  23.020  31.877  1.00 65.25  ? 121 VAL V CG2 1 
HETATM 7750 O O5  . A2G G 4 .   ? 30.388  -24.533 20.968  1.00 40.40  ? 1   A2G B O5  1 
HETATM 7751 C C1  . A2G G 4 .   ? 31.378  -24.547 21.978  1.00 50.20  ? 1   A2G B C1  1 
HETATM 7752 C C2  . A2G G 4 .   ? 30.804  -24.069 23.309  1.00 46.82  ? 1   A2G B C2  1 
HETATM 7753 N N2  . A2G G 4 .   ? 31.813  -24.147 24.349  1.00 39.13  ? 1   A2G B N2  1 
HETATM 7754 C C3  . A2G G 4 .   ? 29.574  -24.891 23.689  1.00 42.53  ? 1   A2G B C3  1 
HETATM 7755 O O3  . A2G G 4 .   ? 28.966  -24.331 24.848  1.00 47.20  ? 1   A2G B O3  1 
HETATM 7756 C C4  . A2G G 4 .   ? 28.580  -24.918 22.535  1.00 45.50  ? 1   A2G B C4  1 
HETATM 7757 O O4  . A2G G 4 .   ? 28.041  -23.618 22.317  1.00 47.93  ? 1   A2G B O4  1 
HETATM 7758 C C5  . A2G G 4 .   ? 29.279  -25.395 21.265  1.00 46.46  ? 1   A2G B C5  1 
HETATM 7759 C C6  . A2G G 4 .   ? 28.390  -25.408 20.048  1.00 43.27  ? 1   A2G B C6  1 
HETATM 7760 O O6  . A2G G 4 .   ? 28.914  -26.398 19.164  1.00 46.99  ? 1   A2G B O6  1 
HETATM 7761 C C7  . A2G G 4 .   ? 32.392  -23.069 24.892  1.00 41.64  ? 1   A2G B C7  1 
HETATM 7762 O O7  . A2G G 4 .   ? 32.095  -21.929 24.546  1.00 42.77  ? 1   A2G B O7  1 
HETATM 7763 C C8  . A2G G 4 .   ? 33.421  -23.337 25.950  1.00 37.02  ? 1   A2G B C8  1 
HETATM 7764 C C1  . SIA G 4 .   ? 26.958  -26.752 17.854  1.00 53.89  ? 2   SIA B C1  1 
HETATM 7765 C C2  . SIA G 4 .   ? 28.448  -26.351 17.844  1.00 49.50  ? 2   SIA B C2  1 
HETATM 7766 C C3  . SIA G 4 .   ? 29.320  -27.360 17.110  1.00 42.74  ? 2   SIA B C3  1 
HETATM 7767 C C4  . SIA G 4 .   ? 29.104  -27.278 15.600  1.00 53.19  ? 2   SIA B C4  1 
HETATM 7768 C C5  . SIA G 4 .   ? 29.357  -25.841 15.150  1.00 47.92  ? 2   SIA B C5  1 
HETATM 7769 C C6  . SIA G 4 .   ? 28.406  -24.907 15.892  1.00 46.45  ? 2   SIA B C6  1 
HETATM 7770 C C7  . SIA G 4 .   ? 28.589  -23.429 15.557  1.00 47.55  ? 2   SIA B C7  1 
HETATM 7771 C C8  . SIA G 4 .   ? 27.740  -22.495 16.421  1.00 42.13  ? 2   SIA B C8  1 
HETATM 7772 C C9  . SIA G 4 .   ? 27.941  -21.037 16.046  1.00 41.87  ? 2   SIA B C9  1 
HETATM 7773 C C10 . SIA G 4 .   ? 30.037  -24.973 12.958  1.00 47.26  ? 2   SIA B C10 1 
HETATM 7774 C C11 . SIA G 4 .   ? 29.759  -24.970 11.484  1.00 43.05  ? 2   SIA B C11 1 
HETATM 7775 N N5  . SIA G 4 .   ? 29.215  -25.716 13.709  1.00 47.28  ? 2   SIA B N5  1 
HETATM 7776 O O1A . SIA G 4 .   ? 26.143  -25.808 17.831  1.00 54.70  ? 2   SIA B O1A 1 
HETATM 7777 O O1B . SIA G 4 .   ? 26.694  -27.963 17.901  1.00 58.58  ? 2   SIA B O1B 1 
HETATM 7778 O O4  . SIA G 4 .   ? 30.007  -28.152 14.922  1.00 48.93  ? 2   SIA B O4  1 
HETATM 7779 O O6  . SIA G 4 .   ? 28.593  -25.052 17.310  1.00 43.61  ? 2   SIA B O6  1 
HETATM 7780 O O7  . SIA G 4 .   ? 29.961  -23.084 15.708  1.00 40.42  ? 2   SIA B O7  1 
HETATM 7781 O O8  . SIA G 4 .   ? 26.360  -22.831 16.278  1.00 39.78  ? 2   SIA B O8  1 
HETATM 7782 O O9  . SIA G 4 .   ? 27.160  -20.181 16.870  1.00 36.47  ? 2   SIA B O9  1 
HETATM 7783 O O10 . SIA G 4 .   ? 30.954  -24.320 13.449  1.00 45.86  ? 2   SIA B O10 1 
HETATM 7784 O O5  . A2G H 4 .   ? -8.928  25.048  -45.170 1.00 84.36  ? 1   A2G C O5  1 
HETATM 7785 C C1  . A2G H 4 .   ? -7.931  25.231  -46.159 1.00 87.88  ? 1   A2G C C1  1 
HETATM 7786 C C2  . A2G H 4 .   ? -8.483  24.919  -47.547 1.00 84.38  ? 1   A2G C C2  1 
HETATM 7787 N N2  . A2G H 4 .   ? -7.473  25.154  -48.566 1.00 84.79  ? 1   A2G C N2  1 
HETATM 7788 C C3  . A2G H 4 .   ? -9.733  25.748  -47.827 1.00 86.55  ? 1   A2G C C3  1 
HETATM 7789 O O3  . A2G H 4 .   ? -10.312 25.335  -49.060 1.00 87.92  ? 1   A2G C O3  1 
HETATM 7790 C C4  . A2G H 4 .   ? -10.736 25.576  -46.693 1.00 89.70  ? 1   A2G C C4  1 
HETATM 7791 O O4  . A2G H 4 .   ? -11.226 24.239  -46.670 1.00 89.99  ? 1   A2G C O4  1 
HETATM 7792 C C5  . A2G H 4 .   ? -10.075 25.893  -45.354 1.00 88.25  ? 1   A2G C C5  1 
HETATM 7793 C C6  . A2G H 4 .   ? -11.009 25.619  -44.202 1.00 89.32  ? 1   A2G C C6  1 
HETATM 7794 O O6  . A2G H 4 .   ? -10.633 26.473  -43.122 1.00 88.47  ? 1   A2G C O6  1 
HETATM 7795 C C7  . A2G H 4 .   ? -6.875  24.167  -49.242 1.00 86.80  ? 1   A2G C C7  1 
HETATM 7796 O O7  . A2G H 4 .   ? -7.147  22.985  -49.045 1.00 88.95  ? 1   A2G C O7  1 
HETATM 7797 C C8  . A2G H 4 .   ? -5.851  24.589  -50.255 1.00 89.76  ? 1   A2G C C8  1 
HETATM 7798 C C1  . SIA H 4 .   ? -12.695 26.385  -41.912 1.00 95.37  ? 2   SIA C C1  1 
HETATM 7799 C C2  . SIA H 4 .   ? -11.172 26.145  -41.869 1.00 93.26  ? 2   SIA C C2  1 
HETATM 7800 C C3  . SIA H 4 .   ? -10.474 27.054  -40.871 1.00 93.55  ? 2   SIA C C3  1 
HETATM 7801 C C4  . SIA H 4 .   ? -10.818 26.659  -39.436 1.00 92.82  ? 2   SIA C C4  1 
HETATM 7802 C C5  . SIA H 4 .   ? -10.460 25.188  -39.233 1.00 93.60  ? 2   SIA C C5  1 
HETATM 7803 C C6  . SIA H 4 .   ? -11.232 24.338  -40.239 1.00 90.20  ? 2   SIA C C6  1 
HETATM 7804 C C7  . SIA H 4 .   ? -10.909 22.847  -40.179 1.00 83.71  ? 2   SIA C C7  1 
HETATM 7805 C C8  . SIA H 4 .   ? -11.574 22.036  -41.294 1.00 84.12  ? 2   SIA C C8  1 
HETATM 7806 C C9  . SIA H 4 .   ? -11.236 20.559  -41.204 1.00 83.77  ? 2   SIA C C9  1 
HETATM 7807 C C10 . SIA H 4 .   ? -9.920  23.979  -37.164 1.00 85.33  ? 2   SIA C C10 1 
HETATM 7808 C C11 . SIA H 4 .   ? -10.351 23.668  -35.760 1.00 85.96  ? 2   SIA C C11 1 
HETATM 7809 N N5  . SIA H 4 .   ? -10.735 24.776  -37.866 1.00 92.49  ? 2   SIA C N5  1 
HETATM 7810 O O1A . SIA H 4 .   ? -13.398 25.384  -42.161 1.00 94.04  ? 2   SIA C O1A 1 
HETATM 7811 O O1B . SIA H 4 .   ? -13.095 27.540  -41.703 1.00 97.62  ? 2   SIA C O1B 1 
HETATM 7812 O O4  . SIA H 4 .   ? -10.082 27.459  -38.511 1.00 96.83  ? 2   SIA C O4  1 
HETATM 7813 O O6  . SIA H 4 .   ? -10.936 24.777  -41.573 1.00 93.35  ? 2   SIA C O6  1 
HETATM 7814 O O7  . SIA H 4 .   ? -9.498  22.676  -40.260 1.00 81.35  ? 2   SIA C O7  1 
HETATM 7815 O O8  . SIA H 4 .   ? -12.991 22.193  -41.220 1.00 84.42  ? 2   SIA C O8  1 
HETATM 7816 O O9  . SIA H 4 .   ? -11.843 19.827  -42.260 1.00 81.84  ? 2   SIA C O9  1 
HETATM 7817 O O10 . SIA H 4 .   ? -8.884  23.525  -37.642 1.00 82.67  ? 2   SIA C O10 1 
HETATM 7818 N N   . SER I 5 .   ? -5.488  28.811  -46.058 1.00 87.95  ? 301 SER H N   1 
HETATM 7819 C CA  . SER I 5 .   ? -6.233  28.297  -44.876 1.00 88.02  ? 301 SER H CA  1 
HETATM 7820 C C   . SER I 5 .   ? -5.413  28.552  -43.606 1.00 88.55  ? 301 SER H C   1 
HETATM 7821 O O   . SER I 5 .   ? -6.030  29.022  -42.619 1.00 87.28  ? 301 SER H O   1 
HETATM 7822 C CB  . SER I 5 .   ? -6.557  26.830  -45.057 1.00 86.84  ? 301 SER H CB  1 
HETATM 7823 O OG  . SER I 5 .   ? -7.440  26.539  -46.145 1.00 91.65  ? 301 SER H OG  1 
HETATM 7824 O OXT . SER I 5 .   ? -4.195  28.278  -43.642 1.00 86.63  ? 301 SER H OXT 1 
HETATM 7825 C C1  . GOL J 6 .   ? -17.698 8.058   -25.888 1.00 73.00  ? 302 GOL H C1  1 
HETATM 7826 O O1  . GOL J 6 .   ? -18.858 8.756   -26.275 1.00 72.35  ? 302 GOL H O1  1 
HETATM 7827 C C2  . GOL J 6 .   ? -17.858 6.593   -26.236 1.00 77.06  ? 302 GOL H C2  1 
HETATM 7828 O O2  . GOL J 6 .   ? -18.755 6.007   -25.319 1.00 82.32  ? 302 GOL H O2  1 
HETATM 7829 C C3  . GOL J 6 .   ? -18.366 6.452   -27.662 1.00 73.67  ? 302 GOL H C3  1 
HETATM 7830 O O3  . GOL J 6 .   ? -18.358 5.078   -27.985 1.00 73.04  ? 302 GOL H O3  1 
HETATM 7831 C C1  . PEG K 7 .   ? -8.520  -8.326  -15.469 1.00 48.15  ? 303 PEG H C1  1 
HETATM 7832 O O1  . PEG K 7 .   ? -9.233  -7.171  -15.088 1.00 52.93  ? 303 PEG H O1  1 
HETATM 7833 C C2  . PEG K 7 .   ? -7.195  -8.361  -14.754 1.00 48.87  ? 303 PEG H C2  1 
HETATM 7834 O O2  . PEG K 7 .   ? -6.288  -9.166  -15.463 1.00 56.48  ? 303 PEG H O2  1 
HETATM 7835 C C3  . PEG K 7 .   ? -5.783  -10.215 -14.679 1.00 61.37  ? 303 PEG H C3  1 
HETATM 7836 C C4  . PEG K 7 .   ? -4.887  -11.096 -15.511 1.00 48.12  ? 303 PEG H C4  1 
HETATM 7837 O O4  . PEG K 7 .   ? -4.372  -12.133 -14.708 1.00 55.10  ? 303 PEG H O4  1 
HETATM 7838 N N   . SER L 5 .   ? 33.826  -28.119 22.274  1.00 54.54  ? 301 SER I N   1 
HETATM 7839 C CA  . SER L 5 .   ? 33.061  -27.740 21.054  1.00 56.89  ? 301 SER I CA  1 
HETATM 7840 C C   . SER L 5 .   ? 33.849  -28.152 19.805  1.00 55.81  ? 301 SER I C   1 
HETATM 7841 O O   . SER L 5 .   ? 33.205  -28.732 18.897  1.00 54.99  ? 301 SER I O   1 
HETATM 7842 C CB  . SER L 5 .   ? 32.749  -26.258 21.066  1.00 52.91  ? 301 SER I CB  1 
HETATM 7843 O OG  . SER L 5 .   ? 31.876  -25.844 22.122  1.00 53.43  ? 301 SER I OG  1 
HETATM 7844 O OXT . SER L 5 .   ? 35.068  -27.885 19.778  1.00 60.68  ? 301 SER I OXT 1 
HETATM 7845 C C1  . GOL M 6 .   ? 24.385  11.758  10.218  1.00 36.03  ? 302 GOL I C1  1 
HETATM 7846 O O1  . GOL M 6 .   ? 25.169  10.920  9.405   1.00 53.69  ? 302 GOL I O1  1 
HETATM 7847 C C2  . GOL M 6 .   ? 24.365  11.227  11.636  1.00 43.04  ? 302 GOL I C2  1 
HETATM 7848 O O2  . GOL M 6 .   ? 23.367  11.907  12.363  1.00 45.08  ? 302 GOL I O2  1 
HETATM 7849 C C3  . GOL M 6 .   ? 24.113  9.729   11.631  1.00 49.97  ? 302 GOL I C3  1 
HETATM 7850 O O3  . GOL M 6 .   ? 23.995  9.317   12.975  1.00 48.15  ? 302 GOL I O3  1 
HETATM 7851 C C1  . GOL N 6 .   ? 34.289  -0.448  -0.769  1.00 53.57  ? 303 GOL I C1  1 
HETATM 7852 O O1  . GOL N 6 .   ? 33.183  -1.046  -0.136  1.00 54.76  ? 303 GOL I O1  1 
HETATM 7853 C C2  . GOL N 6 .   ? 34.853  -1.408  -1.796  1.00 49.53  ? 303 GOL I C2  1 
HETATM 7854 O O2  . GOL N 6 .   ? 36.122  -0.943  -2.193  1.00 61.83  ? 303 GOL I O2  1 
HETATM 7855 C C3  . GOL N 6 .   ? 34.941  -2.803  -1.200  1.00 47.33  ? 303 GOL I C3  1 
HETATM 7856 O O3  . GOL N 6 .   ? 33.977  -3.615  -1.835  1.00 48.78  ? 303 GOL I O3  1 
HETATM 7857 C C1  . GOL O 6 .   ? 30.156  27.322  12.463  1.00 51.46  ? 304 GOL I C1  1 
HETATM 7858 O O1  . GOL O 6 .   ? 29.382  26.197  12.804  1.00 55.36  ? 304 GOL I O1  1 
HETATM 7859 C C2  . GOL O 6 .   ? 30.520  27.253  10.995  1.00 47.40  ? 304 GOL I C2  1 
HETATM 7860 O O2  . GOL O 6 .   ? 30.016  28.401  10.352  1.00 54.47  ? 304 GOL I O2  1 
HETATM 7861 C C3  . GOL O 6 .   ? 32.030  27.151  10.837  1.00 47.57  ? 304 GOL I C3  1 
HETATM 7862 O O3  . GOL O 6 .   ? 32.316  27.095  9.457   1.00 44.27  ? 304 GOL I O3  1 
HETATM 7863 C C1  . PEG P 7 .   ? 26.698  -5.729  4.046   1.00 41.80  ? 305 PEG I C1  1 
HETATM 7864 O O1  . PEG P 7 .   ? 25.817  -4.833  4.684   1.00 54.97  ? 305 PEG I O1  1 
HETATM 7865 C C2  . PEG P 7 .   ? 27.427  -5.010  2.940   1.00 51.22  ? 305 PEG I C2  1 
HETATM 7866 O O2  . PEG P 7 .   ? 27.264  -5.700  1.729   1.00 53.87  ? 305 PEG I O2  1 
HETATM 7867 C C3  . PEG P 7 .   ? 27.875  -5.044  0.647   1.00 42.81  ? 305 PEG I C3  1 
HETATM 7868 C C4  . PEG P 7 .   ? 29.345  -4.867  0.915   1.00 47.05  ? 305 PEG I C4  1 
HETATM 7869 O O4  . PEG P 7 .   ? 30.083  -5.239  -0.227  1.00 40.23  ? 305 PEG I O4  1 
HETATM 7870 C C1  . GOL Q 6 .   ? 7.019   -1.685  20.805  1.00 59.44  ? 301 GOL L C1  1 
HETATM 7871 O O1  . GOL Q 6 .   ? 7.667   -0.621  21.460  1.00 63.44  ? 301 GOL L O1  1 
HETATM 7872 C C2  . GOL Q 6 .   ? 7.457   -1.702  19.358  1.00 49.53  ? 301 GOL L C2  1 
HETATM 7873 O O2  . GOL Q 6 .   ? 8.839   -1.429  19.314  1.00 51.41  ? 301 GOL L O2  1 
HETATM 7874 C C3  . GOL Q 6 .   ? 7.147   -3.055  18.739  1.00 54.05  ? 301 GOL L C3  1 
HETATM 7875 O O3  . GOL Q 6 .   ? 7.602   -3.021  17.404  1.00 47.58  ? 301 GOL L O3  1 
HETATM 7876 C C1  . GOL R 6 .   ? 10.125  6.499   3.361   1.00 48.39  ? 302 GOL L C1  1 
HETATM 7877 O O1  . GOL R 6 .   ? 9.996   6.472   1.960   1.00 44.98  ? 302 GOL L O1  1 
HETATM 7878 C C2  . GOL R 6 .   ? 9.889   5.107   3.908   1.00 49.14  ? 302 GOL L C2  1 
HETATM 7879 O O2  . GOL R 6 .   ? 11.040  4.328   3.674   1.00 48.64  ? 302 GOL L O2  1 
HETATM 7880 C C3  . GOL R 6 .   ? 9.570   5.190   5.392   1.00 43.30  ? 302 GOL L C3  1 
HETATM 7881 O O3  . GOL R 6 .   ? 9.186   3.906   5.829   1.00 55.97  ? 302 GOL L O3  1 
HETATM 7882 C C1  . GOL S 6 .   ? -18.407 -14.277 -30.057 1.00 39.24  ? 301 GOL M C1  1 
HETATM 7883 O O1  . GOL S 6 .   ? -19.550 -13.646 -29.530 1.00 40.30  ? 301 GOL M O1  1 
HETATM 7884 C C2  . GOL S 6 .   ? -17.281 -13.279 -30.196 1.00 42.78  ? 301 GOL M C2  1 
HETATM 7885 O O2  . GOL S 6 .   ? -16.646 -13.137 -28.944 1.00 39.07  ? 301 GOL M O2  1 
HETATM 7886 C C3  . GOL S 6 .   ? -16.302 -13.760 -31.254 1.00 33.96  ? 301 GOL M C3  1 
HETATM 7887 O O3  . GOL S 6 .   ? -15.271 -12.802 -31.346 1.00 39.35  ? 301 GOL M O3  1 
HETATM 7888 C C1  . GOL T 6 .   ? -8.974  18.383  9.346   1.00 51.65  ? 201 GOL V C1  1 
HETATM 7889 O O1  . GOL T 6 .   ? -9.693  17.444  8.581   1.00 56.06  ? 201 GOL V O1  1 
HETATM 7890 C C2  . GOL T 6 .   ? -7.499  18.261  9.025   1.00 51.82  ? 201 GOL V C2  1 
HETATM 7891 O O2  . GOL T 6 .   ? -7.276  18.752  7.723   1.00 73.55  ? 201 GOL V O2  1 
HETATM 7892 C C3  . GOL T 6 .   ? -6.672  19.016  10.054  1.00 60.30  ? 201 GOL V C3  1 
HETATM 7893 O O3  . GOL T 6 .   ? -5.312  18.877  9.706   1.00 62.18  ? 201 GOL V O3  1 
HETATM 7894 O O   . HOH U 8 .   ? 0.495   28.039  -45.337 1.00 69.02  ? 401 HOH H O   1 
HETATM 7895 O O   . HOH U 8 .   ? -13.490 -13.655 -18.546 1.00 38.80  ? 402 HOH H O   1 
HETATM 7896 O O   . HOH U 8 .   ? -10.635 -5.447  -29.702 1.00 46.40  ? 403 HOH H O   1 
HETATM 7897 O O   . HOH U 8 .   ? -3.515  -2.346  -17.576 1.00 46.04  ? 404 HOH H O   1 
HETATM 7898 O O   . HOH U 8 .   ? -9.633  -4.564  -19.961 1.00 31.74  ? 405 HOH H O   1 
HETATM 7899 O O   . HOH U 8 .   ? -6.835  -9.847  -31.577 1.00 45.41  ? 406 HOH H O   1 
HETATM 7900 O O   . HOH U 8 .   ? -0.714  -26.689 -37.554 1.00 51.18  ? 407 HOH H O   1 
HETATM 7901 O O   . HOH U 8 .   ? -6.213  4.007   -37.988 1.00 53.68  ? 408 HOH H O   1 
HETATM 7902 O O   . HOH U 8 .   ? -9.808  -0.011  -11.999 1.00 46.77  ? 409 HOH H O   1 
HETATM 7903 O O   . HOH U 8 .   ? -2.445  29.197  -45.344 1.00 67.37  ? 410 HOH H O   1 
HETATM 7904 O O   . HOH U 8 .   ? -10.009 4.492   -35.766 1.00 49.08  ? 411 HOH H O   1 
HETATM 7905 O O   . HOH U 8 .   ? 3.433   -7.760  -19.421 1.00 50.49  ? 412 HOH H O   1 
HETATM 7906 O O   . HOH U 8 .   ? -17.155 -20.279 -43.575 1.00 37.03  ? 413 HOH H O   1 
HETATM 7907 O O   . HOH U 8 .   ? -7.282  -15.448 -38.677 1.00 41.17  ? 414 HOH H O   1 
HETATM 7908 O O   . HOH U 8 .   ? -19.456 -39.653 -31.804 1.00 54.01  ? 415 HOH H O   1 
HETATM 7909 O O   . HOH U 8 .   ? -16.103 -15.573 -18.630 1.00 41.88  ? 416 HOH H O   1 
HETATM 7910 O O   . HOH U 8 .   ? -16.484 -5.582  -26.805 1.00 42.33  ? 417 HOH H O   1 
HETATM 7911 O O   . HOH U 8 .   ? -10.791 -0.686  -21.659 1.00 44.56  ? 418 HOH H O   1 
HETATM 7912 O O   . HOH U 8 .   ? 0.122   -11.165 -30.150 1.00 39.34  ? 419 HOH H O   1 
HETATM 7913 O O   . HOH U 8 .   ? -7.605  -22.827 -47.858 1.00 44.60  ? 420 HOH H O   1 
HETATM 7914 O O   . HOH U 8 .   ? -14.296 4.202   -25.487 1.00 48.76  ? 421 HOH H O   1 
HETATM 7915 O O   . HOH U 8 .   ? -4.922  -19.980 -41.487 1.00 41.00  ? 422 HOH H O   1 
HETATM 7916 O O   . HOH U 8 .   ? -1.157  -17.426 -34.922 1.00 38.69  ? 423 HOH H O   1 
HETATM 7917 O O   . HOH U 8 .   ? -16.794 -14.954 -26.667 1.00 34.25  ? 424 HOH H O   1 
HETATM 7918 O O   . HOH U 8 .   ? -5.534  -13.666 -36.744 1.00 40.17  ? 425 HOH H O   1 
HETATM 7919 O O   . HOH U 8 .   ? -18.925 -10.428 -20.339 1.00 40.19  ? 426 HOH H O   1 
HETATM 7920 O O   . HOH U 8 .   ? -9.631  -3.241  -22.289 1.00 32.16  ? 427 HOH H O   1 
HETATM 7921 O O   . HOH U 8 .   ? -9.584  -8.398  -32.569 1.00 37.65  ? 428 HOH H O   1 
HETATM 7922 O O   . HOH U 8 .   ? -6.075  -4.163  -25.742 1.00 39.00  ? 429 HOH H O   1 
HETATM 7923 O O   . HOH U 8 .   ? 0.424   -6.282  -16.814 1.00 42.90  ? 430 HOH H O   1 
HETATM 7924 O O   . HOH U 8 .   ? -12.377 -5.538  -31.369 1.00 42.71  ? 431 HOH H O   1 
HETATM 7925 O O   . HOH U 8 .   ? -15.863 -23.672 -26.733 1.00 39.91  ? 432 HOH H O   1 
HETATM 7926 O O   . HOH U 8 .   ? -13.029 0.109   -23.300 1.00 48.97  ? 433 HOH H O   1 
HETATM 7927 O O   . HOH U 8 .   ? -7.161  -13.066 -38.233 1.00 57.15  ? 434 HOH H O   1 
HETATM 7928 O O   . HOH U 8 .   ? -1.624  27.802  -46.944 1.00 54.09  ? 435 HOH H O   1 
HETATM 7929 O O   . HOH V 8 .   ? 24.602  7.305   -12.756 1.00 44.39  ? 401 HOH I O   1 
HETATM 7930 O O   . HOH V 8 .   ? 23.970  28.505  -5.885  1.00 57.17  ? 402 HOH I O   1 
HETATM 7931 O O   . HOH V 8 .   ? 8.047   30.364  -5.892  1.00 45.77  ? 403 HOH I O   1 
HETATM 7932 O O   . HOH V 8 .   ? 44.162  -17.393 -5.118  1.00 59.23  ? 404 HOH I O   1 
HETATM 7933 O O   . HOH V 8 .   ? 16.226  24.651  -2.486  1.00 49.10  ? 405 HOH I O   1 
HETATM 7934 O O   . HOH V 8 .   ? 33.473  -31.847 9.064   1.00 52.13  ? 406 HOH I O   1 
HETATM 7935 O O   . HOH V 8 .   ? 37.582  7.575   -0.919  1.00 40.84  ? 407 HOH I O   1 
HETATM 7936 O O   . HOH V 8 .   ? 26.705  28.134  9.919   1.00 44.98  ? 408 HOH I O   1 
HETATM 7937 O O   . HOH V 8 .   ? 21.222  22.977  -6.467  1.00 49.81  ? 409 HOH I O   1 
HETATM 7938 O O   . HOH V 8 .   ? 32.600  18.704  8.970   1.00 47.29  ? 410 HOH I O   1 
HETATM 7939 O O   . HOH V 8 .   ? 15.907  31.084  -8.522  1.00 67.29  ? 411 HOH I O   1 
HETATM 7940 O O   . HOH V 8 .   ? 36.326  -28.303 -1.346  1.00 54.42  ? 412 HOH I O   1 
HETATM 7941 O O   . HOH V 8 .   ? 34.023  -0.999  -16.246 1.00 35.44  ? 413 HOH I O   1 
HETATM 7942 O O   . HOH V 8 .   ? 29.735  -31.552 10.726  1.00 47.41  ? 414 HOH I O   1 
HETATM 7943 O O   . HOH V 8 .   ? 45.703  -24.278 19.780  1.00 42.95  ? 415 HOH I O   1 
HETATM 7944 O O   . HOH V 8 .   ? 28.476  29.514  0.752   1.00 44.50  ? 416 HOH I O   1 
HETATM 7945 O O   . HOH V 8 .   ? 40.017  -22.188 -0.702  1.00 39.40  ? 417 HOH I O   1 
HETATM 7946 O O   . HOH V 8 .   ? 28.281  -1.211  -9.565  1.00 34.32  ? 418 HOH I O   1 
HETATM 7947 O O   . HOH V 8 .   ? 37.734  -9.919  -10.816 1.00 45.99  ? 419 HOH I O   1 
HETATM 7948 O O   . HOH V 8 .   ? 19.860  -8.818  2.915   1.00 36.56  ? 420 HOH I O   1 
HETATM 7949 O O   . HOH V 8 .   ? 38.915  -11.407 15.768  1.00 37.96  ? 421 HOH I O   1 
HETATM 7950 O O   . HOH V 8 .   ? 26.172  -15.394 -7.286  1.00 47.25  ? 422 HOH I O   1 
HETATM 7951 O O   . HOH V 8 .   ? 25.614  2.681   1.066   1.00 43.37  ? 423 HOH I O   1 
HETATM 7952 O O   . HOH V 8 .   ? 37.278  9.711   -12.807 1.00 38.61  ? 424 HOH I O   1 
HETATM 7953 O O   . HOH V 8 .   ? 41.549  -26.240 10.449  1.00 43.55  ? 425 HOH I O   1 
HETATM 7954 O O   . HOH V 8 .   ? 23.975  -9.334  -2.643  1.00 45.54  ? 426 HOH I O   1 
HETATM 7955 O O   . HOH V 8 .   ? 24.927  15.672  12.625  1.00 44.71  ? 427 HOH I O   1 
HETATM 7956 O O   . HOH V 8 .   ? 28.502  -6.445  7.656   1.00 36.30  ? 428 HOH I O   1 
HETATM 7957 O O   . HOH V 8 .   ? 26.239  31.078  2.313   1.00 42.03  ? 429 HOH I O   1 
HETATM 7958 O O   . HOH V 8 .   ? 44.719  -12.087 6.892   1.00 47.43  ? 430 HOH I O   1 
HETATM 7959 O O   . HOH V 8 .   ? 37.838  1.518   -2.124  1.00 39.88  ? 431 HOH I O   1 
HETATM 7960 O O   . HOH V 8 .   ? 22.407  9.194   -13.780 1.00 49.18  ? 432 HOH I O   1 
HETATM 7961 O O   . HOH V 8 .   ? 20.651  18.600  10.217  1.00 41.96  ? 433 HOH I O   1 
HETATM 7962 O O   . HOH V 8 .   ? 38.293  -1.837  -16.552 1.00 35.83  ? 434 HOH I O   1 
HETATM 7963 O O   . HOH V 8 .   ? 36.644  24.288  3.181   1.00 37.90  ? 435 HOH I O   1 
HETATM 7964 O O   . HOH V 8 .   ? 31.898  -12.814 19.676  1.00 34.76  ? 436 HOH I O   1 
HETATM 7965 O O   . HOH V 8 .   ? 29.478  -2.929  -1.711  1.00 38.13  ? 437 HOH I O   1 
HETATM 7966 O O   . HOH V 8 .   ? 34.849  -3.787  -10.470 1.00 41.44  ? 438 HOH I O   1 
HETATM 7967 O O   . HOH V 8 .   ? 34.815  -29.769 15.143  1.00 47.19  ? 439 HOH I O   1 
HETATM 7968 O O   . HOH V 8 .   ? 36.801  15.188  2.661   1.00 40.07  ? 440 HOH I O   1 
HETATM 7969 O O   . HOH V 8 .   ? 32.772  11.449  5.250   1.00 40.94  ? 441 HOH I O   1 
HETATM 7970 O O   . HOH V 8 .   ? 33.222  -25.459 16.298  1.00 45.92  ? 442 HOH I O   1 
HETATM 7971 O O   . HOH V 8 .   ? 31.846  -0.347  -3.932  1.00 36.69  ? 443 HOH I O   1 
HETATM 7972 O O   . HOH V 8 .   ? 48.473  -23.866 12.658  1.00 49.99  ? 444 HOH I O   1 
HETATM 7973 O O   . HOH V 8 .   ? 27.417  1.250   0.421   1.00 46.87  ? 445 HOH I O   1 
HETATM 7974 O O   . HOH V 8 .   ? 26.977  -2.134  -3.123  1.00 37.13  ? 446 HOH I O   1 
HETATM 7975 O O   . HOH V 8 .   ? 44.051  -27.115 2.455   1.00 40.38  ? 447 HOH I O   1 
HETATM 7976 O O   . HOH V 8 .   ? 21.680  0.665   -3.203  1.00 38.22  ? 448 HOH I O   1 
HETATM 7977 O O   . HOH V 8 .   ? 27.543  -4.459  -7.081  1.00 37.93  ? 449 HOH I O   1 
HETATM 7978 O O   . HOH V 8 .   ? 28.491  -2.099  -7.047  1.00 32.36  ? 450 HOH I O   1 
HETATM 7979 O O   . HOH V 8 .   ? 30.423  6.679   1.522   1.00 42.71  ? 451 HOH I O   1 
HETATM 7980 O O   . HOH V 8 .   ? 44.840  -11.963 13.165  1.00 49.90  ? 452 HOH I O   1 
HETATM 7981 O O   . HOH V 8 .   ? 32.614  18.291  -9.764  1.00 41.08  ? 453 HOH I O   1 
HETATM 7982 O O   . HOH V 8 .   ? 27.696  -4.549  -12.604 1.00 36.76  ? 454 HOH I O   1 
HETATM 7983 O O   . HOH V 8 .   ? 26.291  26.126  12.031  1.00 48.08  ? 455 HOH I O   1 
HETATM 7984 O O   . HOH V 8 .   ? 21.980  19.049  -7.224  1.00 44.57  ? 456 HOH I O   1 
HETATM 7985 O O   . HOH V 8 .   ? 19.869  -11.075 0.459   1.00 55.00  ? 457 HOH I O   1 
HETATM 7986 O O   . HOH V 8 .   ? 26.895  -3.254  -10.071 1.00 37.32  ? 458 HOH I O   1 
HETATM 7987 O O   . HOH V 8 .   ? 26.432  -2.209  1.058   1.00 51.03  ? 459 HOH I O   1 
HETATM 7988 O O   . HOH V 8 .   ? 25.299  16.638  14.650  1.00 43.96  ? 460 HOH I O   1 
HETATM 7989 O O   . HOH V 8 .   ? 21.395  -9.263  -1.527  1.00 45.14  ? 461 HOH I O   1 
HETATM 7990 O O   . HOH V 8 .   ? 24.890  -3.136  -3.547  1.00 47.30  ? 462 HOH I O   1 
HETATM 7991 O O   . HOH W 8 .   ? -42.723 -3.743  -58.853 1.00 51.25  ? 201 HOH K O   1 
HETATM 7992 O O   . HOH W 8 .   ? -45.427 -9.555  -39.500 1.00 40.20  ? 202 HOH K O   1 
HETATM 7993 O O   . HOH W 8 .   ? -40.006 -3.959  -41.226 1.00 38.73  ? 203 HOH K O   1 
HETATM 7994 O O   . HOH W 8 .   ? -41.612 1.360   -54.782 1.00 46.48  ? 204 HOH K O   1 
HETATM 7995 O O   . HOH W 8 .   ? -42.347 3.500   -46.822 1.00 50.71  ? 205 HOH K O   1 
HETATM 7996 O O   . HOH W 8 .   ? -34.239 -17.703 -52.169 1.00 46.64  ? 206 HOH K O   1 
HETATM 7997 O O   . HOH W 8 .   ? -52.269 -15.851 -43.586 1.00 56.78  ? 207 HOH K O   1 
HETATM 7998 O O   . HOH W 8 .   ? -55.676 -10.946 -37.186 1.00 52.71  ? 208 HOH K O   1 
HETATM 7999 O O   . HOH W 8 .   ? -41.907 5.760   -45.038 1.00 59.46  ? 209 HOH K O   1 
HETATM 8000 O O   . HOH W 8 .   ? -35.597 -2.620  -57.350 1.00 44.07  ? 210 HOH K O   1 
HETATM 8001 O O   . HOH X 8 .   ? 8.520   28.012  -7.723  1.00 53.16  ? 401 HOH L O   1 
HETATM 8002 O O   . HOH X 8 .   ? 28.674  -5.337  16.712  1.00 40.84  ? 402 HOH L O   1 
HETATM 8003 O O   . HOH X 8 .   ? 19.375  18.664  -7.023  1.00 36.13  ? 403 HOH L O   1 
HETATM 8004 O O   . HOH X 8 .   ? 31.648  -10.982 24.267  1.00 48.85  ? 404 HOH L O   1 
HETATM 8005 O O   . HOH X 8 .   ? 32.119  -6.630  16.447  1.00 43.61  ? 405 HOH L O   1 
HETATM 8006 O O   . HOH X 8 .   ? 14.412  -5.600  11.646  1.00 44.33  ? 406 HOH L O   1 
HETATM 8007 O O   . HOH X 8 .   ? 0.693   19.012  1.434   1.00 44.40  ? 407 HOH L O   1 
HETATM 8008 O O   . HOH X 8 .   ? 31.055  -12.141 22.398  1.00 47.71  ? 408 HOH L O   1 
HETATM 8009 O O   . HOH X 8 .   ? 19.694  -12.572 8.897   1.00 43.30  ? 409 HOH L O   1 
HETATM 8010 O O   . HOH X 8 .   ? 17.592  -10.590 31.788  1.00 53.90  ? 410 HOH L O   1 
HETATM 8011 O O   . HOH X 8 .   ? 22.457  19.008  -9.509  1.00 42.79  ? 411 HOH L O   1 
HETATM 8012 O O   . HOH X 8 .   ? 5.230   7.658   11.471  1.00 33.29  ? 412 HOH L O   1 
HETATM 8013 O O   . HOH X 8 .   ? 14.111  10.799  -17.708 1.00 46.22  ? 413 HOH L O   1 
HETATM 8014 O O   . HOH X 8 .   ? 17.116  8.703   -8.484  1.00 32.33  ? 414 HOH L O   1 
HETATM 8015 O O   . HOH X 8 .   ? 27.453  -20.091 19.667  1.00 40.79  ? 415 HOH L O   1 
HETATM 8016 O O   . HOH X 8 .   ? 7.562   6.275   1.141   1.00 41.78  ? 416 HOH L O   1 
HETATM 8017 O O   . HOH X 8 .   ? -5.080  15.000  7.899   1.00 41.10  ? 417 HOH L O   1 
HETATM 8018 O O   . HOH X 8 .   ? 19.314  -0.066  16.924  1.00 38.10  ? 418 HOH L O   1 
HETATM 8019 O O   . HOH X 8 .   ? 10.630  31.281  -4.911  1.00 54.66  ? 419 HOH L O   1 
HETATM 8020 O O   . HOH X 8 .   ? 22.887  -5.536  11.662  1.00 33.68  ? 420 HOH L O   1 
HETATM 8021 O O   . HOH X 8 .   ? 14.042  -11.328 17.666  1.00 41.71  ? 421 HOH L O   1 
HETATM 8022 O O   . HOH X 8 .   ? 20.731  7.384   19.533  1.00 44.33  ? 422 HOH L O   1 
HETATM 8023 O O   . HOH X 8 .   ? 0.569   13.363  8.302   1.00 31.92  ? 423 HOH L O   1 
HETATM 8024 O O   . HOH X 8 .   ? 18.699  12.444  12.430  1.00 35.80  ? 424 HOH L O   1 
HETATM 8025 O O   . HOH X 8 .   ? 25.059  -3.957  24.479  1.00 39.24  ? 425 HOH L O   1 
HETATM 8026 O O   . HOH X 8 .   ? 27.133  -28.737 5.339   1.00 43.78  ? 426 HOH L O   1 
HETATM 8027 O O   . HOH X 8 .   ? 6.755   -0.567  12.567  1.00 43.04  ? 427 HOH L O   1 
HETATM 8028 O O   . HOH X 8 .   ? 3.333   18.349  -8.803  1.00 41.09  ? 428 HOH L O   1 
HETATM 8029 O O   . HOH X 8 .   ? 7.516   9.031   22.506  1.00 35.95  ? 429 HOH L O   1 
HETATM 8030 O O   . HOH X 8 .   ? 23.159  -19.653 6.753   1.00 31.02  ? 430 HOH L O   1 
HETATM 8031 O O   . HOH X 8 .   ? 29.587  -20.893 21.381  1.00 41.14  ? 431 HOH L O   1 
HETATM 8032 O O   . HOH X 8 .   ? 10.395  3.854   14.967  1.00 28.48  ? 432 HOH L O   1 
HETATM 8033 O O   . HOH X 8 .   ? 11.286  8.257   -2.130  1.00 44.16  ? 433 HOH L O   1 
HETATM 8034 O O   . HOH X 8 .   ? 19.531  3.183   13.712  1.00 37.75  ? 434 HOH L O   1 
HETATM 8035 O O   . HOH X 8 .   ? 32.163  -5.345  9.788   1.00 34.25  ? 435 HOH L O   1 
HETATM 8036 O O   . HOH X 8 .   ? 20.478  10.585  12.168  1.00 35.51  ? 436 HOH L O   1 
HETATM 8037 O O   . HOH X 8 .   ? 15.852  2.917   9.190   1.00 38.80  ? 437 HOH L O   1 
HETATM 8038 O O   . HOH X 8 .   ? 9.913   1.683   14.054  1.00 36.31  ? 438 HOH L O   1 
HETATM 8039 O O   . HOH X 8 .   ? 18.768  10.181  -2.036  1.00 37.90  ? 439 HOH L O   1 
HETATM 8040 O O   . HOH X 8 .   ? 19.591  2.653   16.295  1.00 41.30  ? 440 HOH L O   1 
HETATM 8041 O O   . HOH X 8 .   ? 33.959  -2.859  11.527  1.00 36.04  ? 441 HOH L O   1 
HETATM 8042 O O   . HOH X 8 .   ? 13.104  1.945   13.045  1.00 42.41  ? 442 HOH L O   1 
HETATM 8043 O O   . HOH X 8 .   ? 3.386   11.335  1.422   1.00 39.08  ? 443 HOH L O   1 
HETATM 8044 O O   . HOH X 8 .   ? 32.585  -15.378 22.624  1.00 36.44  ? 444 HOH L O   1 
HETATM 8045 O O   . HOH X 8 .   ? 20.816  -18.101 7.527   1.00 40.59  ? 445 HOH L O   1 
HETATM 8046 O O   . HOH X 8 .   ? 21.936  3.570   7.349   1.00 36.55  ? 446 HOH L O   1 
HETATM 8047 O O   . HOH X 8 .   ? 19.245  3.696   3.469   1.00 43.07  ? 447 HOH L O   1 
HETATM 8048 O O   . HOH X 8 .   ? 19.443  7.997   -7.344  1.00 38.30  ? 448 HOH L O   1 
HETATM 8049 O O   . HOH X 8 .   ? 24.205  7.158   8.981   1.00 36.44  ? 449 HOH L O   1 
HETATM 8050 O O   . HOH X 8 .   ? 9.135   -6.402  25.252  1.00 44.42  ? 450 HOH L O   1 
HETATM 8051 O O   . HOH X 8 .   ? 14.702  1.340   11.094  1.00 39.45  ? 451 HOH L O   1 
HETATM 8052 O O   . HOH X 8 .   ? 2.136   21.869  2.737   1.00 42.47  ? 452 HOH L O   1 
HETATM 8053 O O   . HOH X 8 .   ? 18.380  3.464   9.729   1.00 34.64  ? 453 HOH L O   1 
HETATM 8054 O O   . HOH X 8 .   ? 8.726   0.602   16.080  1.00 42.65  ? 454 HOH L O   1 
HETATM 8055 O O   . HOH X 8 .   ? 28.912  -30.615 14.729  1.00 43.11  ? 455 HOH L O   1 
HETATM 8056 O O   . HOH X 8 .   ? 6.642   5.452   -0.761  1.00 49.62  ? 456 HOH L O   1 
HETATM 8057 O O   . HOH X 8 .   ? 23.450  -3.127  11.994  1.00 47.43  ? 457 HOH L O   1 
HETATM 8058 O O   . HOH Y 8 .   ? -29.103 10.910  -49.346 1.00 68.04  ? 401 HOH M O   1 
HETATM 8059 O O   . HOH Y 8 .   ? -18.475 -23.116 -26.793 1.00 39.77  ? 402 HOH M O   1 
HETATM 8060 O O   . HOH Y 8 .   ? -28.706 -1.051  -46.679 1.00 47.79  ? 403 HOH M O   1 
HETATM 8061 O O   . HOH Y 8 .   ? -20.835 -14.223 -23.250 1.00 33.63  ? 404 HOH M O   1 
HETATM 8062 O O   . HOH Y 8 .   ? -29.161 -32.634 -21.013 1.00 48.12  ? 405 HOH M O   1 
HETATM 8063 O O   . HOH Y 8 .   ? -15.651 -24.426 -23.989 1.00 42.28  ? 406 HOH M O   1 
HETATM 8064 O O   . HOH Y 8 .   ? -32.437 -9.129  -42.678 1.00 32.90  ? 407 HOH M O   1 
HETATM 8065 O O   . HOH Y 8 .   ? -17.198 -11.452 -43.674 1.00 35.00  ? 408 HOH M O   1 
HETATM 8066 O O   . HOH Y 8 .   ? -26.925 -4.991  -45.434 1.00 39.42  ? 409 HOH M O   1 
HETATM 8067 O O   . HOH Y 8 .   ? -30.271 -7.782  -53.523 1.00 35.41  ? 410 HOH M O   1 
HETATM 8068 O O   . HOH Y 8 .   ? -26.550 -10.126 -23.699 1.00 40.26  ? 411 HOH M O   1 
HETATM 8069 O O   . HOH Y 8 .   ? -22.517 -14.175 -18.904 1.00 42.36  ? 412 HOH M O   1 
HETATM 8070 O O   . HOH Y 8 .   ? -23.605 -35.676 -29.148 1.00 51.09  ? 413 HOH M O   1 
HETATM 8071 O O   . HOH Y 8 .   ? -22.091 -4.808  -39.239 1.00 44.21  ? 414 HOH M O   1 
HETATM 8072 O O   . HOH Y 8 .   ? -36.787 -33.506 -17.291 1.00 45.17  ? 415 HOH M O   1 
HETATM 8073 O O   . HOH Y 8 .   ? -17.939 -3.923  -44.054 1.00 43.72  ? 416 HOH M O   1 
HETATM 8074 O O   . HOH Y 8 .   ? -25.672 -10.654 -27.481 1.00 37.65  ? 417 HOH M O   1 
HETATM 8075 O O   . HOH Y 8 .   ? -25.901 -11.976 -29.364 1.00 45.31  ? 418 HOH M O   1 
HETATM 8076 O O   . HOH Y 8 .   ? -28.659 -13.225 -24.005 1.00 36.08  ? 419 HOH M O   1 
HETATM 8077 O O   . HOH Y 8 .   ? -19.152 -13.590 -44.345 1.00 37.17  ? 420 HOH M O   1 
HETATM 8078 O O   . HOH Y 8 .   ? -13.828 -8.901  -40.275 1.00 41.51  ? 421 HOH M O   1 
HETATM 8079 O O   . HOH Y 8 .   ? -30.496 -13.846 -26.404 1.00 42.64  ? 422 HOH M O   1 
HETATM 8080 O O   . HOH Y 8 .   ? -15.924 -5.746  -37.916 1.00 41.29  ? 423 HOH M O   1 
HETATM 8081 O O   . HOH Y 8 .   ? -37.262 -14.771 -40.511 1.00 43.00  ? 424 HOH M O   1 
HETATM 8082 O O   . HOH Y 8 .   ? -30.463 -21.506 -42.741 1.00 38.28  ? 425 HOH M O   1 
HETATM 8083 O O   . HOH Y 8 .   ? -34.342 -23.822 -25.358 1.00 30.06  ? 426 HOH M O   1 
HETATM 8084 O O   . HOH Y 8 .   ? -35.607 -24.197 -37.329 1.00 44.96  ? 427 HOH M O   1 
HETATM 8085 O O   . HOH Y 8 .   ? -21.960 -30.155 -22.559 1.00 45.80  ? 428 HOH M O   1 
HETATM 8086 O O   . HOH Y 8 .   ? -27.307 -7.982  -34.758 1.00 47.55  ? 429 HOH M O   1 
HETATM 8087 O O   . HOH Y 8 .   ? -34.964 -27.188 -29.367 1.00 48.44  ? 430 HOH M O   1 
HETATM 8088 O O   . HOH Y 8 .   ? -22.287 -7.912  -27.631 1.00 40.36  ? 431 HOH M O   1 
HETATM 8089 O O   . HOH Y 8 .   ? -30.616 -18.116 -48.871 1.00 39.78  ? 432 HOH M O   1 
HETATM 8090 O O   . HOH Y 8 .   ? -19.500 -5.270  -40.031 1.00 40.32  ? 433 HOH M O   1 
HETATM 8091 O O   . HOH Y 8 .   ? -28.194 -2.875  -44.795 1.00 48.09  ? 434 HOH M O   1 
HETATM 8092 O O   . HOH Y 8 .   ? -30.692 -36.083 -23.058 1.00 60.04  ? 435 HOH M O   1 
HETATM 8093 O O   . HOH Y 8 .   ? -28.708 -23.534 -41.308 1.00 37.59  ? 436 HOH M O   1 
HETATM 8094 O O   . HOH Y 8 .   ? -37.348 -24.041 -39.416 1.00 56.53  ? 437 HOH M O   1 
HETATM 8095 O O   . HOH Y 8 .   ? -39.936 -15.306 -39.351 1.00 42.32  ? 438 HOH M O   1 
HETATM 8096 O O   . HOH Z 8 .   ? -4.575  6.657   29.155  1.00 47.84  ? 301 HOH V O   1 
HETATM 8097 O O   . HOH Z 8 .   ? -2.518  2.797   11.551  1.00 38.63  ? 302 HOH V O   1 
HETATM 8098 O O   . HOH Z 8 .   ? -7.738  7.942   8.688   1.00 46.30  ? 303 HOH V O   1 
HETATM 8099 O O   . HOH Z 8 .   ? -1.046  0.678   22.222  1.00 45.51  ? 304 HOH V O   1 
HETATM 8100 O O   . HOH Z 8 .   ? 4.186   10.161  28.702  1.00 36.08  ? 305 HOH V O   1 
HETATM 8101 O O   . HOH Z 8 .   ? 5.953   0.806   16.837  1.00 33.67  ? 306 HOH V O   1 
HETATM 8102 O O   . HOH Z 8 .   ? -5.616  19.711  5.563   1.00 55.38  ? 307 HOH V O   1 
HETATM 8103 O O   . HOH Z 8 .   ? -12.129 17.828  12.328  1.00 48.68  ? 308 HOH V O   1 
HETATM 8104 O O   . HOH Z 8 .   ? 0.892   -0.937  23.377  1.00 47.91  ? 309 HOH V O   1 
HETATM 8105 O O   . HOH Z 8 .   ? -18.578 7.716   17.536  1.00 47.43  ? 310 HOH V O   1 
HETATM 8106 O O   . HOH Z 8 .   ? -17.482 9.209   6.310   1.00 58.56  ? 311 HOH V O   1 
HETATM 8107 O O   . HOH Z 8 .   ? -0.006  -4.419  8.739   1.00 46.82  ? 312 HOH V O   1 
HETATM 8108 O O   . HOH Z 8 .   ? -7.752  -0.522  6.483   1.00 42.61  ? 313 HOH V O   1 
HETATM 8109 O O   . HOH Z 8 .   ? -7.053  29.739  38.641  1.00 51.59  ? 314 HOH V O   1 
HETATM 8110 O O   . HOH Z 8 .   ? -8.784  31.075  37.449  1.00 51.42  ? 315 HOH V O   1 
# 
