data_9FX2
# 
_entry.id   9FX2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FX2         pdb_00009fx2 10.2210/pdb9fx2/pdb 
WWPDB D_1292139824 ?            ?                   
EMDB  EMD-50841    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-19 ? 
2 'EM metadata'     1 0 2025-03-19 ? 
3 'Half map'        1 0 2025-03-19 1 
4 'Half map'        1 0 2025-03-19 2 
5 Image             1 0 2025-03-19 ? 
6 'Primary map'     1 0 2025-03-19 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FX2 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of methylamine activated CD109' 
_pdbx_database_related.db_id          EMD-50841 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              gra@mbg.au.dk 
_pdbx_contact_author.name_first         Gregers 
_pdbx_contact_author.name_last          Andersen 
_pdbx_contact_author.name_mi            R. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6292-3319 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Almeida, A.V.'  1 0000-0002-3235-4183 
'Andersen, G.R.' 2 0000-0001-6292-3319 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of methylamine activated CD109' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Almeida, A.V.'  1 0000-0002-3235-4183 
primary 'Andersen, G.R.' 2 0000-0001-6292-3319 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'CD109 antigen'                          140449.797 1 ? ? ? ? 
2 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208    5 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;150 kDa TGF-beta-1-binding protein,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7,Platelet-specific Gov antigen,p180,r150
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SGSVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSA
DEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ
WLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGK
PVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNV
STNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKI
NYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSY
MVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI
SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNA
EYAERENLYFQGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTT
PVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATV
LFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQIT
AIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFG
NYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLG
YRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPR
SLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPV
KFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRR
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SGSVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSA
DEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ
WLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGK
PVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNV
STNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKI
NYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSY
MVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI
SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNA
EYAERENLYFQGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTT
PVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATV
LFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQIT
AIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFG
NYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLG
YRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPR
SLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPV
KFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRR
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    SER n 
1 2    GLY n 
1 3    SER n 
1 4    VAL n 
1 5    ALA n 
1 6    PRO n 
1 7    GLY n 
1 8    PRO n 
1 9    ARG n 
1 10   PHE n 
1 11   LEU n 
1 12   VAL n 
1 13   THR n 
1 14   ALA n 
1 15   PRO n 
1 16   GLY n 
1 17   ILE n 
1 18   ILE n 
1 19   ARG n 
1 20   PRO n 
1 21   GLY n 
1 22   GLY n 
1 23   ASN n 
1 24   VAL n 
1 25   THR n 
1 26   ILE n 
1 27   GLY n 
1 28   VAL n 
1 29   GLU n 
1 30   LEU n 
1 31   LEU n 
1 32   GLU n 
1 33   HIS n 
1 34   CYS n 
1 35   PRO n 
1 36   SER n 
1 37   GLN n 
1 38   VAL n 
1 39   THR n 
1 40   VAL n 
1 41   LYS n 
1 42   ALA n 
1 43   GLU n 
1 44   LEU n 
1 45   LEU n 
1 46   LYS n 
1 47   THR n 
1 48   ALA n 
1 49   SER n 
1 50   ASN n 
1 51   LEU n 
1 52   THR n 
1 53   VAL n 
1 54   SER n 
1 55   VAL n 
1 56   LEU n 
1 57   GLU n 
1 58   ALA n 
1 59   GLU n 
1 60   GLY n 
1 61   VAL n 
1 62   PHE n 
1 63   GLU n 
1 64   LYS n 
1 65   GLY n 
1 66   SER n 
1 67   PHE n 
1 68   LYS n 
1 69   THR n 
1 70   LEU n 
1 71   THR n 
1 72   LEU n 
1 73   PRO n 
1 74   SER n 
1 75   LEU n 
1 76   PRO n 
1 77   LEU n 
1 78   ASN n 
1 79   SER n 
1 80   ALA n 
1 81   ASP n 
1 82   GLU n 
1 83   ILE n 
1 84   TYR n 
1 85   GLU n 
1 86   LEU n 
1 87   ARG n 
1 88   VAL n 
1 89   THR n 
1 90   GLY n 
1 91   ARG n 
1 92   THR n 
1 93   GLN n 
1 94   ASP n 
1 95   GLU n 
1 96   ILE n 
1 97   LEU n 
1 98   PHE n 
1 99   SER n 
1 100  ASN n 
1 101  SER n 
1 102  THR n 
1 103  ARG n 
1 104  LEU n 
1 105  SER n 
1 106  PHE n 
1 107  GLU n 
1 108  THR n 
1 109  LYS n 
1 110  ARG n 
1 111  ILE n 
1 112  SER n 
1 113  VAL n 
1 114  PHE n 
1 115  ILE n 
1 116  GLN n 
1 117  THR n 
1 118  ASP n 
1 119  LYS n 
1 120  ALA n 
1 121  LEU n 
1 122  TYR n 
1 123  LYS n 
1 124  PRO n 
1 125  LYS n 
1 126  GLN n 
1 127  GLU n 
1 128  VAL n 
1 129  LYS n 
1 130  PHE n 
1 131  ARG n 
1 132  ILE n 
1 133  VAL n 
1 134  THR n 
1 135  LEU n 
1 136  PHE n 
1 137  SER n 
1 138  ASP n 
1 139  PHE n 
1 140  LYS n 
1 141  PRO n 
1 142  TYR n 
1 143  LYS n 
1 144  THR n 
1 145  SER n 
1 146  LEU n 
1 147  ASN n 
1 148  ILE n 
1 149  LEU n 
1 150  ILE n 
1 151  LYS n 
1 152  ASP n 
1 153  PRO n 
1 154  LYS n 
1 155  SER n 
1 156  ASN n 
1 157  LEU n 
1 158  ILE n 
1 159  GLN n 
1 160  GLN n 
1 161  TRP n 
1 162  LEU n 
1 163  SER n 
1 164  GLN n 
1 165  GLN n 
1 166  SER n 
1 167  ASP n 
1 168  LEU n 
1 169  GLY n 
1 170  VAL n 
1 171  ILE n 
1 172  SER n 
1 173  LYS n 
1 174  THR n 
1 175  PHE n 
1 176  GLN n 
1 177  LEU n 
1 178  SER n 
1 179  SER n 
1 180  HIS n 
1 181  PRO n 
1 182  ILE n 
1 183  LEU n 
1 184  GLY n 
1 185  ASP n 
1 186  TRP n 
1 187  SER n 
1 188  ILE n 
1 189  GLN n 
1 190  VAL n 
1 191  GLN n 
1 192  VAL n 
1 193  ASN n 
1 194  ASP n 
1 195  GLN n 
1 196  THR n 
1 197  TYR n 
1 198  TYR n 
1 199  GLN n 
1 200  SER n 
1 201  PHE n 
1 202  GLN n 
1 203  VAL n 
1 204  SER n 
1 205  GLU n 
1 206  TYR n 
1 207  VAL n 
1 208  LEU n 
1 209  PRO n 
1 210  LYS n 
1 211  PHE n 
1 212  GLU n 
1 213  VAL n 
1 214  THR n 
1 215  LEU n 
1 216  GLN n 
1 217  THR n 
1 218  PRO n 
1 219  LEU n 
1 220  TYR n 
1 221  CYS n 
1 222  SER n 
1 223  MET n 
1 224  ASN n 
1 225  SER n 
1 226  LYS n 
1 227  HIS n 
1 228  LEU n 
1 229  ASN n 
1 230  GLY n 
1 231  THR n 
1 232  ILE n 
1 233  THR n 
1 234  ALA n 
1 235  LYS n 
1 236  TYR n 
1 237  THR n 
1 238  TYR n 
1 239  GLY n 
1 240  LYS n 
1 241  PRO n 
1 242  VAL n 
1 243  LYS n 
1 244  GLY n 
1 245  ASP n 
1 246  VAL n 
1 247  THR n 
1 248  LEU n 
1 249  THR n 
1 250  PHE n 
1 251  LEU n 
1 252  PRO n 
1 253  LEU n 
1 254  SER n 
1 255  PHE n 
1 256  TRP n 
1 257  GLY n 
1 258  LYS n 
1 259  LYS n 
1 260  LYS n 
1 261  ASN n 
1 262  ILE n 
1 263  THR n 
1 264  LYS n 
1 265  THR n 
1 266  PHE n 
1 267  LYS n 
1 268  ILE n 
1 269  ASN n 
1 270  GLY n 
1 271  SER n 
1 272  ALA n 
1 273  ASN n 
1 274  PHE n 
1 275  SER n 
1 276  PHE n 
1 277  ASN n 
1 278  ASP n 
1 279  GLU n 
1 280  GLU n 
1 281  MET n 
1 282  LYS n 
1 283  ASN n 
1 284  VAL n 
1 285  MET n 
1 286  ASP n 
1 287  SER n 
1 288  SER n 
1 289  ASN n 
1 290  GLY n 
1 291  LEU n 
1 292  SER n 
1 293  GLU n 
1 294  TYR n 
1 295  LEU n 
1 296  ASP n 
1 297  LEU n 
1 298  SER n 
1 299  SER n 
1 300  PRO n 
1 301  GLY n 
1 302  PRO n 
1 303  VAL n 
1 304  GLU n 
1 305  ILE n 
1 306  LEU n 
1 307  THR n 
1 308  THR n 
1 309  VAL n 
1 310  THR n 
1 311  GLU n 
1 312  SER n 
1 313  VAL n 
1 314  THR n 
1 315  GLY n 
1 316  ILE n 
1 317  SER n 
1 318  ARG n 
1 319  ASN n 
1 320  VAL n 
1 321  SER n 
1 322  THR n 
1 323  ASN n 
1 324  VAL n 
1 325  PHE n 
1 326  PHE n 
1 327  LYS n 
1 328  GLN n 
1 329  HIS n 
1 330  ASP n 
1 331  TYR n 
1 332  ILE n 
1 333  ILE n 
1 334  GLU n 
1 335  PHE n 
1 336  PHE n 
1 337  ASP n 
1 338  TYR n 
1 339  THR n 
1 340  THR n 
1 341  VAL n 
1 342  LEU n 
1 343  LYS n 
1 344  PRO n 
1 345  SER n 
1 346  LEU n 
1 347  ASN n 
1 348  PHE n 
1 349  THR n 
1 350  ALA n 
1 351  THR n 
1 352  VAL n 
1 353  LYS n 
1 354  VAL n 
1 355  THR n 
1 356  ARG n 
1 357  ALA n 
1 358  ASP n 
1 359  GLY n 
1 360  ASN n 
1 361  GLN n 
1 362  LEU n 
1 363  THR n 
1 364  LEU n 
1 365  GLU n 
1 366  GLU n 
1 367  ARG n 
1 368  ARG n 
1 369  ASN n 
1 370  ASN n 
1 371  VAL n 
1 372  VAL n 
1 373  ILE n 
1 374  THR n 
1 375  VAL n 
1 376  THR n 
1 377  GLN n 
1 378  ARG n 
1 379  ASN n 
1 380  TYR n 
1 381  THR n 
1 382  GLU n 
1 383  TYR n 
1 384  TRP n 
1 385  SER n 
1 386  GLY n 
1 387  SER n 
1 388  ASN n 
1 389  SER n 
1 390  GLY n 
1 391  ASN n 
1 392  GLN n 
1 393  LYS n 
1 394  MET n 
1 395  GLU n 
1 396  ALA n 
1 397  VAL n 
1 398  GLN n 
1 399  LYS n 
1 400  ILE n 
1 401  ASN n 
1 402  TYR n 
1 403  THR n 
1 404  VAL n 
1 405  PRO n 
1 406  GLN n 
1 407  SER n 
1 408  GLY n 
1 409  THR n 
1 410  PHE n 
1 411  LYS n 
1 412  ILE n 
1 413  GLU n 
1 414  PHE n 
1 415  PRO n 
1 416  ILE n 
1 417  LEU n 
1 418  GLU n 
1 419  ASP n 
1 420  SER n 
1 421  SER n 
1 422  GLU n 
1 423  LEU n 
1 424  GLN n 
1 425  LEU n 
1 426  LYS n 
1 427  ALA n 
1 428  TYR n 
1 429  PHE n 
1 430  LEU n 
1 431  GLY n 
1 432  SER n 
1 433  LYS n 
1 434  SER n 
1 435  SER n 
1 436  MET n 
1 437  ALA n 
1 438  VAL n 
1 439  HIS n 
1 440  SER n 
1 441  LEU n 
1 442  PHE n 
1 443  LYS n 
1 444  SER n 
1 445  PRO n 
1 446  SER n 
1 447  LYS n 
1 448  THR n 
1 449  TYR n 
1 450  ILE n 
1 451  GLN n 
1 452  LEU n 
1 453  LYS n 
1 454  THR n 
1 455  ARG n 
1 456  ASP n 
1 457  GLU n 
1 458  ASN n 
1 459  ILE n 
1 460  LYS n 
1 461  VAL n 
1 462  GLY n 
1 463  SER n 
1 464  PRO n 
1 465  PHE n 
1 466  GLU n 
1 467  LEU n 
1 468  VAL n 
1 469  VAL n 
1 470  SER n 
1 471  GLY n 
1 472  ASN n 
1 473  LYS n 
1 474  ARG n 
1 475  LEU n 
1 476  LYS n 
1 477  GLU n 
1 478  LEU n 
1 479  SER n 
1 480  TYR n 
1 481  MET n 
1 482  VAL n 
1 483  VAL n 
1 484  SER n 
1 485  ARG n 
1 486  GLY n 
1 487  GLN n 
1 488  LEU n 
1 489  VAL n 
1 490  ALA n 
1 491  VAL n 
1 492  GLY n 
1 493  LYS n 
1 494  GLN n 
1 495  ASN n 
1 496  SER n 
1 497  THR n 
1 498  MET n 
1 499  PHE n 
1 500  SER n 
1 501  LEU n 
1 502  THR n 
1 503  PRO n 
1 504  GLU n 
1 505  ASN n 
1 506  SER n 
1 507  TRP n 
1 508  THR n 
1 509  PRO n 
1 510  LYS n 
1 511  ALA n 
1 512  CYS n 
1 513  VAL n 
1 514  ILE n 
1 515  VAL n 
1 516  TYR n 
1 517  TYR n 
1 518  ILE n 
1 519  GLU n 
1 520  ASP n 
1 521  ASP n 
1 522  GLY n 
1 523  GLU n 
1 524  ILE n 
1 525  ILE n 
1 526  SER n 
1 527  ASP n 
1 528  VAL n 
1 529  LEU n 
1 530  LYS n 
1 531  ILE n 
1 532  PRO n 
1 533  VAL n 
1 534  GLN n 
1 535  LEU n 
1 536  VAL n 
1 537  PHE n 
1 538  LYS n 
1 539  ASN n 
1 540  LYS n 
1 541  ILE n 
1 542  LYS n 
1 543  LEU n 
1 544  TYR n 
1 545  TRP n 
1 546  SER n 
1 547  LYS n 
1 548  VAL n 
1 549  LYS n 
1 550  ALA n 
1 551  GLU n 
1 552  PRO n 
1 553  SER n 
1 554  GLU n 
1 555  LYS n 
1 556  VAL n 
1 557  SER n 
1 558  LEU n 
1 559  ARG n 
1 560  ILE n 
1 561  SER n 
1 562  VAL n 
1 563  THR n 
1 564  GLN n 
1 565  PRO n 
1 566  ASP n 
1 567  SER n 
1 568  ILE n 
1 569  VAL n 
1 570  GLY n 
1 571  ILE n 
1 572  VAL n 
1 573  ALA n 
1 574  VAL n 
1 575  ASP n 
1 576  LYS n 
1 577  SER n 
1 578  VAL n 
1 579  ASN n 
1 580  LEU n 
1 581  MET n 
1 582  ASN n 
1 583  ALA n 
1 584  SER n 
1 585  ASN n 
1 586  ASP n 
1 587  ILE n 
1 588  THR n 
1 589  MET n 
1 590  GLU n 
1 591  ASN n 
1 592  VAL n 
1 593  VAL n 
1 594  HIS n 
1 595  GLU n 
1 596  LEU n 
1 597  GLU n 
1 598  LEU n 
1 599  TYR n 
1 600  ASN n 
1 601  THR n 
1 602  GLY n 
1 603  TYR n 
1 604  TYR n 
1 605  LEU n 
1 606  GLY n 
1 607  MET n 
1 608  PHE n 
1 609  MET n 
1 610  ASN n 
1 611  SER n 
1 612  PHE n 
1 613  ALA n 
1 614  VAL n 
1 615  PHE n 
1 616  GLN n 
1 617  GLU n 
1 618  CYS n 
1 619  GLY n 
1 620  LEU n 
1 621  TRP n 
1 622  VAL n 
1 623  LEU n 
1 624  THR n 
1 625  ASP n 
1 626  ALA n 
1 627  ASN n 
1 628  LEU n 
1 629  THR n 
1 630  LYS n 
1 631  ASP n 
1 632  TYR n 
1 633  ILE n 
1 634  ASP n 
1 635  GLY n 
1 636  VAL n 
1 637  TYR n 
1 638  ASP n 
1 639  ASN n 
1 640  ALA n 
1 641  GLU n 
1 642  TYR n 
1 643  ALA n 
1 644  GLU n 
1 645  ARG n 
1 646  GLU n 
1 647  ASN n 
1 648  LEU n 
1 649  TYR n 
1 650  PHE n 
1 651  GLN n 
1 652  GLY n 
1 653  HIS n 
1 654  ILE n 
1 655  VAL n 
1 656  ASP n 
1 657  ILE n 
1 658  HIS n 
1 659  ASP n 
1 660  PHE n 
1 661  SER n 
1 662  LEU n 
1 663  GLY n 
1 664  SER n 
1 665  SER n 
1 666  PRO n 
1 667  HIS n 
1 668  VAL n 
1 669  ARG n 
1 670  LYS n 
1 671  HIS n 
1 672  PHE n 
1 673  PRO n 
1 674  GLU n 
1 675  THR n 
1 676  TRP n 
1 677  ILE n 
1 678  TRP n 
1 679  LEU n 
1 680  ASP n 
1 681  THR n 
1 682  ASN n 
1 683  MET n 
1 684  GLY n 
1 685  TYR n 
1 686  ARG n 
1 687  ILE n 
1 688  TYR n 
1 689  GLN n 
1 690  GLU n 
1 691  PHE n 
1 692  GLU n 
1 693  VAL n 
1 694  THR n 
1 695  VAL n 
1 696  PRO n 
1 697  ASP n 
1 698  SER n 
1 699  ILE n 
1 700  THR n 
1 701  SER n 
1 702  TRP n 
1 703  VAL n 
1 704  ALA n 
1 705  THR n 
1 706  GLY n 
1 707  PHE n 
1 708  VAL n 
1 709  ILE n 
1 710  SER n 
1 711  GLU n 
1 712  ASP n 
1 713  LEU n 
1 714  GLY n 
1 715  LEU n 
1 716  GLY n 
1 717  LEU n 
1 718  THR n 
1 719  THR n 
1 720  THR n 
1 721  PRO n 
1 722  VAL n 
1 723  GLU n 
1 724  LEU n 
1 725  GLN n 
1 726  ALA n 
1 727  PHE n 
1 728  GLN n 
1 729  PRO n 
1 730  PHE n 
1 731  PHE n 
1 732  ILE n 
1 733  PHE n 
1 734  LEU n 
1 735  ASN n 
1 736  LEU n 
1 737  PRO n 
1 738  TYR n 
1 739  SER n 
1 740  VAL n 
1 741  ILE n 
1 742  ARG n 
1 743  GLY n 
1 744  GLU n 
1 745  GLU n 
1 746  PHE n 
1 747  ALA n 
1 748  LEU n 
1 749  GLU n 
1 750  ILE n 
1 751  THR n 
1 752  ILE n 
1 753  PHE n 
1 754  ASN n 
1 755  TYR n 
1 756  LEU n 
1 757  LYS n 
1 758  ASP n 
1 759  ALA n 
1 760  THR n 
1 761  GLU n 
1 762  VAL n 
1 763  LYS n 
1 764  VAL n 
1 765  ILE n 
1 766  ILE n 
1 767  GLU n 
1 768  LYS n 
1 769  SER n 
1 770  ASP n 
1 771  LYS n 
1 772  PHE n 
1 773  ASP n 
1 774  ILE n 
1 775  LEU n 
1 776  MET n 
1 777  THR n 
1 778  SER n 
1 779  ASN n 
1 780  GLU n 
1 781  ILE n 
1 782  ASN n 
1 783  ALA n 
1 784  THR n 
1 785  GLY n 
1 786  HIS n 
1 787  GLN n 
1 788  GLN n 
1 789  THR n 
1 790  LEU n 
1 791  LEU n 
1 792  VAL n 
1 793  PRO n 
1 794  SER n 
1 795  GLU n 
1 796  ASP n 
1 797  GLY n 
1 798  ALA n 
1 799  THR n 
1 800  VAL n 
1 801  LEU n 
1 802  PHE n 
1 803  PRO n 
1 804  ILE n 
1 805  ARG n 
1 806  PRO n 
1 807  THR n 
1 808  HIS n 
1 809  LEU n 
1 810  GLY n 
1 811  GLU n 
1 812  ILE n 
1 813  PRO n 
1 814  ILE n 
1 815  THR n 
1 816  VAL n 
1 817  THR n 
1 818  ALA n 
1 819  LEU n 
1 820  SER n 
1 821  PRO n 
1 822  THR n 
1 823  ALA n 
1 824  SER n 
1 825  ASP n 
1 826  ALA n 
1 827  VAL n 
1 828  THR n 
1 829  GLN n 
1 830  MET n 
1 831  ILE n 
1 832  LEU n 
1 833  VAL n 
1 834  LYS n 
1 835  ALA n 
1 836  GLU n 
1 837  GLY n 
1 838  ILE n 
1 839  GLU n 
1 840  LYS n 
1 841  SER n 
1 842  TYR n 
1 843  SER n 
1 844  GLN n 
1 845  SER n 
1 846  ILE n 
1 847  LEU n 
1 848  LEU n 
1 849  ASP n 
1 850  LEU n 
1 851  THR n 
1 852  ASP n 
1 853  ASN n 
1 854  ARG n 
1 855  LEU n 
1 856  GLN n 
1 857  SER n 
1 858  THR n 
1 859  LEU n 
1 860  LYS n 
1 861  THR n 
1 862  LEU n 
1 863  SER n 
1 864  PHE n 
1 865  SER n 
1 866  PHE n 
1 867  PRO n 
1 868  PRO n 
1 869  ASN n 
1 870  THR n 
1 871  VAL n 
1 872  THR n 
1 873  GLY n 
1 874  SER n 
1 875  GLU n 
1 876  ARG n 
1 877  VAL n 
1 878  GLN n 
1 879  ILE n 
1 880  THR n 
1 881  ALA n 
1 882  ILE n 
1 883  GLY n 
1 884  ASP n 
1 885  VAL n 
1 886  LEU n 
1 887  GLY n 
1 888  PRO n 
1 889  SER n 
1 890  ILE n 
1 891  ASN n 
1 892  GLY n 
1 893  LEU n 
1 894  ALA n 
1 895  SER n 
1 896  LEU n 
1 897  ILE n 
1 898  ARG n 
1 899  MET n 
1 900  PRO n 
1 901  TYR n 
1 902  GLY n 
1 903  CYS n 
1 904  GLY n 
1 905  GLU n 
1 906  GLN n 
1 907  ASN n 
1 908  MET n 
1 909  ILE n 
1 910  ASN n 
1 911  PHE n 
1 912  ALA n 
1 913  PRO n 
1 914  ASN n 
1 915  ILE n 
1 916  TYR n 
1 917  ILE n 
1 918  LEU n 
1 919  ASP n 
1 920  TYR n 
1 921  LEU n 
1 922  THR n 
1 923  LYS n 
1 924  LYS n 
1 925  LYS n 
1 926  GLN n 
1 927  LEU n 
1 928  THR n 
1 929  ASP n 
1 930  ASN n 
1 931  LEU n 
1 932  LYS n 
1 933  GLU n 
1 934  LYS n 
1 935  ALA n 
1 936  LEU n 
1 937  SER n 
1 938  PHE n 
1 939  MET n 
1 940  ARG n 
1 941  GLN n 
1 942  GLY n 
1 943  TYR n 
1 944  GLN n 
1 945  ARG n 
1 946  GLU n 
1 947  LEU n 
1 948  LEU n 
1 949  TYR n 
1 950  GLN n 
1 951  ARG n 
1 952  GLU n 
1 953  ASP n 
1 954  GLY n 
1 955  SER n 
1 956  PHE n 
1 957  SER n 
1 958  ALA n 
1 959  PHE n 
1 960  GLY n 
1 961  ASN n 
1 962  TYR n 
1 963  ASP n 
1 964  PRO n 
1 965  SER n 
1 966  GLY n 
1 967  SER n 
1 968  THR n 
1 969  TRP n 
1 970  LEU n 
1 971  SER n 
1 972  ALA n 
1 973  PHE n 
1 974  VAL n 
1 975  LEU n 
1 976  ARG n 
1 977  CYS n 
1 978  PHE n 
1 979  LEU n 
1 980  GLU n 
1 981  ALA n 
1 982  ASP n 
1 983  PRO n 
1 984  TYR n 
1 985  ILE n 
1 986  ASP n 
1 987  ILE n 
1 988  ASP n 
1 989  GLN n 
1 990  ASN n 
1 991  VAL n 
1 992  LEU n 
1 993  HIS n 
1 994  ARG n 
1 995  THR n 
1 996  TYR n 
1 997  THR n 
1 998  TRP n 
1 999  LEU n 
1 1000 LYS n 
1 1001 GLY n 
1 1002 HIS n 
1 1003 GLN n 
1 1004 LYS n 
1 1005 SER n 
1 1006 ASN n 
1 1007 GLY n 
1 1008 GLU n 
1 1009 PHE n 
1 1010 TRP n 
1 1011 ASP n 
1 1012 PRO n 
1 1013 GLY n 
1 1014 ARG n 
1 1015 VAL n 
1 1016 ILE n 
1 1017 HIS n 
1 1018 SER n 
1 1019 GLU n 
1 1020 LEU n 
1 1021 GLN n 
1 1022 GLY n 
1 1023 GLY n 
1 1024 ASN n 
1 1025 LYS n 
1 1026 SER n 
1 1027 PRO n 
1 1028 VAL n 
1 1029 THR n 
1 1030 LEU n 
1 1031 THR n 
1 1032 ALA n 
1 1033 TYR n 
1 1034 ILE n 
1 1035 VAL n 
1 1036 THR n 
1 1037 SER n 
1 1038 LEU n 
1 1039 LEU n 
1 1040 GLY n 
1 1041 TYR n 
1 1042 ARG n 
1 1043 LYS n 
1 1044 TYR n 
1 1045 GLN n 
1 1046 PRO n 
1 1047 ASN n 
1 1048 ILE n 
1 1049 ASP n 
1 1050 VAL n 
1 1051 GLN n 
1 1052 GLU n 
1 1053 SER n 
1 1054 ILE n 
1 1055 HIS n 
1 1056 PHE n 
1 1057 LEU n 
1 1058 GLU n 
1 1059 SER n 
1 1060 GLU n 
1 1061 PHE n 
1 1062 SER n 
1 1063 ARG n 
1 1064 GLY n 
1 1065 ILE n 
1 1066 SER n 
1 1067 ASP n 
1 1068 ASN n 
1 1069 TYR n 
1 1070 THR n 
1 1071 LEU n 
1 1072 ALA n 
1 1073 LEU n 
1 1074 ILE n 
1 1075 THR n 
1 1076 TYR n 
1 1077 ALA n 
1 1078 LEU n 
1 1079 SER n 
1 1080 SER n 
1 1081 VAL n 
1 1082 GLY n 
1 1083 SER n 
1 1084 PRO n 
1 1085 LYS n 
1 1086 ALA n 
1 1087 LYS n 
1 1088 GLU n 
1 1089 ALA n 
1 1090 LEU n 
1 1091 ASN n 
1 1092 MET n 
1 1093 LEU n 
1 1094 THR n 
1 1095 TRP n 
1 1096 ARG n 
1 1097 ALA n 
1 1098 GLU n 
1 1099 GLN n 
1 1100 GLU n 
1 1101 GLY n 
1 1102 GLY n 
1 1103 MET n 
1 1104 GLN n 
1 1105 PHE n 
1 1106 TRP n 
1 1107 VAL n 
1 1108 SER n 
1 1109 SER n 
1 1110 GLU n 
1 1111 SER n 
1 1112 LYS n 
1 1113 LEU n 
1 1114 SER n 
1 1115 ASP n 
1 1116 SER n 
1 1117 TRP n 
1 1118 GLN n 
1 1119 PRO n 
1 1120 ARG n 
1 1121 SER n 
1 1122 LEU n 
1 1123 ASP n 
1 1124 ILE n 
1 1125 GLU n 
1 1126 VAL n 
1 1127 ALA n 
1 1128 ALA n 
1 1129 TYR n 
1 1130 ALA n 
1 1131 LEU n 
1 1132 LEU n 
1 1133 SER n 
1 1134 HIS n 
1 1135 PHE n 
1 1136 LEU n 
1 1137 GLN n 
1 1138 PHE n 
1 1139 GLN n 
1 1140 THR n 
1 1141 SER n 
1 1142 GLU n 
1 1143 GLY n 
1 1144 ILE n 
1 1145 PRO n 
1 1146 ILE n 
1 1147 MET n 
1 1148 ARG n 
1 1149 TRP n 
1 1150 LEU n 
1 1151 SER n 
1 1152 ARG n 
1 1153 GLN n 
1 1154 ARG n 
1 1155 ASN n 
1 1156 SER n 
1 1157 LEU n 
1 1158 GLY n 
1 1159 GLY n 
1 1160 PHE n 
1 1161 ALA n 
1 1162 SER n 
1 1163 THR n 
1 1164 GLN n 
1 1165 ASP n 
1 1166 THR n 
1 1167 THR n 
1 1168 VAL n 
1 1169 ALA n 
1 1170 LEU n 
1 1171 LYS n 
1 1172 ALA n 
1 1173 LEU n 
1 1174 SER n 
1 1175 GLU n 
1 1176 PHE n 
1 1177 ALA n 
1 1178 ALA n 
1 1179 LEU n 
1 1180 MET n 
1 1181 ASN n 
1 1182 THR n 
1 1183 GLU n 
1 1184 ARG n 
1 1185 THR n 
1 1186 ASN n 
1 1187 ILE n 
1 1188 GLN n 
1 1189 VAL n 
1 1190 THR n 
1 1191 VAL n 
1 1192 THR n 
1 1193 GLY n 
1 1194 PRO n 
1 1195 SER n 
1 1196 SER n 
1 1197 PRO n 
1 1198 SER n 
1 1199 PRO n 
1 1200 VAL n 
1 1201 LYS n 
1 1202 PHE n 
1 1203 LEU n 
1 1204 ILE n 
1 1205 ASP n 
1 1206 THR n 
1 1207 HIS n 
1 1208 ASN n 
1 1209 ARG n 
1 1210 LEU n 
1 1211 LEU n 
1 1212 LEU n 
1 1213 GLN n 
1 1214 THR n 
1 1215 ALA n 
1 1216 GLU n 
1 1217 LEU n 
1 1218 ALA n 
1 1219 VAL n 
1 1220 VAL n 
1 1221 GLN n 
1 1222 PRO n 
1 1223 THR n 
1 1224 ALA n 
1 1225 VAL n 
1 1226 ASN n 
1 1227 ILE n 
1 1228 SER n 
1 1229 ALA n 
1 1230 ASN n 
1 1231 GLY n 
1 1232 PHE n 
1 1233 GLY n 
1 1234 PHE n 
1 1235 ALA n 
1 1236 ILE n 
1 1237 CYS n 
1 1238 GLN n 
1 1239 LEU n 
1 1240 ASN n 
1 1241 VAL n 
1 1242 VAL n 
1 1243 TYR n 
1 1244 ASN n 
1 1245 VAL n 
1 1246 LYS n 
1 1247 ALA n 
1 1248 SER n 
1 1249 GLY n 
1 1250 SER n 
1 1251 SER n 
1 1252 ARG n 
1 1253 ARG n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1253 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'CD109, CPAMD7' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    SER 1    19   ?    ?   ?   A . n 
A 1 2    GLY 2    20   ?    ?   ?   A . n 
A 1 3    SER 3    21   ?    ?   ?   A . n 
A 1 4    VAL 4    22   ?    ?   ?   A . n 
A 1 5    ALA 5    23   23   ALA ALA A . n 
A 1 6    PRO 6    24   24   PRO PRO A . n 
A 1 7    GLY 7    25   25   GLY GLY A . n 
A 1 8    PRO 8    26   26   PRO PRO A . n 
A 1 9    ARG 9    27   27   ARG ARG A . n 
A 1 10   PHE 10   28   28   PHE PHE A . n 
A 1 11   LEU 11   29   29   LEU LEU A . n 
A 1 12   VAL 12   30   30   VAL VAL A . n 
A 1 13   THR 13   31   31   THR THR A . n 
A 1 14   ALA 14   32   32   ALA ALA A . n 
A 1 15   PRO 15   33   33   PRO PRO A . n 
A 1 16   GLY 16   34   34   GLY GLY A . n 
A 1 17   ILE 17   35   35   ILE ILE A . n 
A 1 18   ILE 18   36   36   ILE ILE A . n 
A 1 19   ARG 19   37   37   ARG ARG A . n 
A 1 20   PRO 20   38   38   PRO PRO A . n 
A 1 21   GLY 21   39   39   GLY GLY A . n 
A 1 22   GLY 22   40   40   GLY GLY A . n 
A 1 23   ASN 23   41   41   ASN ASN A . n 
A 1 24   VAL 24   42   42   VAL VAL A . n 
A 1 25   THR 25   43   43   THR THR A . n 
A 1 26   ILE 26   44   44   ILE ILE A . n 
A 1 27   GLY 27   45   45   GLY GLY A . n 
A 1 28   VAL 28   46   46   VAL VAL A . n 
A 1 29   GLU 29   47   47   GLU GLU A . n 
A 1 30   LEU 30   48   48   LEU LEU A . n 
A 1 31   LEU 31   49   49   LEU LEU A . n 
A 1 32   GLU 32   50   50   GLU GLU A . n 
A 1 33   HIS 33   51   51   HIS HIS A . n 
A 1 34   CYS 34   52   52   CYS CYS A . n 
A 1 35   PRO 35   53   53   PRO PRO A . n 
A 1 36   SER 36   54   54   SER SER A . n 
A 1 37   GLN 37   55   55   GLN GLN A . n 
A 1 38   VAL 38   56   56   VAL VAL A . n 
A 1 39   THR 39   57   57   THR THR A . n 
A 1 40   VAL 40   58   58   VAL VAL A . n 
A 1 41   LYS 41   59   59   LYS LYS A . n 
A 1 42   ALA 42   60   60   ALA ALA A . n 
A 1 43   GLU 43   61   61   GLU GLU A . n 
A 1 44   LEU 44   62   62   LEU LEU A . n 
A 1 45   LEU 45   63   63   LEU LEU A . n 
A 1 46   LYS 46   64   64   LYS LYS A . n 
A 1 47   THR 47   65   65   THR THR A . n 
A 1 48   ALA 48   66   66   ALA ALA A . n 
A 1 49   SER 49   67   67   SER SER A . n 
A 1 50   ASN 50   68   68   ASN ASN A . n 
A 1 51   LEU 51   69   69   LEU LEU A . n 
A 1 52   THR 52   70   70   THR THR A . n 
A 1 53   VAL 53   71   71   VAL VAL A . n 
A 1 54   SER 54   72   72   SER SER A . n 
A 1 55   VAL 55   73   73   VAL VAL A . n 
A 1 56   LEU 56   74   74   LEU LEU A . n 
A 1 57   GLU 57   75   75   GLU GLU A . n 
A 1 58   ALA 58   76   76   ALA ALA A . n 
A 1 59   GLU 59   77   77   GLU GLU A . n 
A 1 60   GLY 60   78   78   GLY GLY A . n 
A 1 61   VAL 61   79   79   VAL VAL A . n 
A 1 62   PHE 62   80   80   PHE PHE A . n 
A 1 63   GLU 63   81   81   GLU GLU A . n 
A 1 64   LYS 64   82   82   LYS LYS A . n 
A 1 65   GLY 65   83   83   GLY GLY A . n 
A 1 66   SER 66   84   84   SER SER A . n 
A 1 67   PHE 67   85   85   PHE PHE A . n 
A 1 68   LYS 68   86   86   LYS LYS A . n 
A 1 69   THR 69   87   87   THR THR A . n 
A 1 70   LEU 70   88   88   LEU LEU A . n 
A 1 71   THR 71   89   89   THR THR A . n 
A 1 72   LEU 72   90   90   LEU LEU A . n 
A 1 73   PRO 73   91   91   PRO PRO A . n 
A 1 74   SER 74   92   92   SER SER A . n 
A 1 75   LEU 75   93   93   LEU LEU A . n 
A 1 76   PRO 76   94   94   PRO PRO A . n 
A 1 77   LEU 77   95   95   LEU LEU A . n 
A 1 78   ASN 78   96   96   ASN ASN A . n 
A 1 79   SER 79   97   97   SER SER A . n 
A 1 80   ALA 80   98   98   ALA ALA A . n 
A 1 81   ASP 81   99   99   ASP ASP A . n 
A 1 82   GLU 82   100  100  GLU GLU A . n 
A 1 83   ILE 83   101  101  ILE ILE A . n 
A 1 84   TYR 84   102  102  TYR TYR A . n 
A 1 85   GLU 85   103  103  GLU GLU A . n 
A 1 86   LEU 86   104  104  LEU LEU A . n 
A 1 87   ARG 87   105  105  ARG ARG A . n 
A 1 88   VAL 88   106  106  VAL VAL A . n 
A 1 89   THR 89   107  107  THR THR A . n 
A 1 90   GLY 90   108  108  GLY GLY A . n 
A 1 91   ARG 91   109  109  ARG ARG A . n 
A 1 92   THR 92   110  110  THR THR A . n 
A 1 93   GLN 93   111  111  GLN GLN A . n 
A 1 94   ASP 94   112  112  ASP ASP A . n 
A 1 95   GLU 95   113  113  GLU GLU A . n 
A 1 96   ILE 96   114  114  ILE ILE A . n 
A 1 97   LEU 97   115  115  LEU LEU A . n 
A 1 98   PHE 98   116  116  PHE PHE A . n 
A 1 99   SER 99   117  117  SER SER A . n 
A 1 100  ASN 100  118  118  ASN ASN A . n 
A 1 101  SER 101  119  119  SER SER A . n 
A 1 102  THR 102  120  120  THR THR A . n 
A 1 103  ARG 103  121  121  ARG ARG A . n 
A 1 104  LEU 104  122  122  LEU LEU A . n 
A 1 105  SER 105  123  123  SER SER A . n 
A 1 106  PHE 106  124  124  PHE PHE A . n 
A 1 107  GLU 107  125  125  GLU GLU A . n 
A 1 108  THR 108  126  126  THR THR A . n 
A 1 109  LYS 109  127  127  LYS LYS A . n 
A 1 110  ARG 110  128  128  ARG ARG A . n 
A 1 111  ILE 111  129  129  ILE ILE A . n 
A 1 112  SER 112  130  130  SER SER A . n 
A 1 113  VAL 113  131  131  VAL VAL A . n 
A 1 114  PHE 114  132  132  PHE PHE A . n 
A 1 115  ILE 115  133  133  ILE ILE A . n 
A 1 116  GLN 116  134  134  GLN GLN A . n 
A 1 117  THR 117  135  135  THR THR A . n 
A 1 118  ASP 118  136  136  ASP ASP A . n 
A 1 119  LYS 119  137  137  LYS LYS A . n 
A 1 120  ALA 120  138  138  ALA ALA A . n 
A 1 121  LEU 121  139  139  LEU LEU A . n 
A 1 122  TYR 122  140  140  TYR TYR A . n 
A 1 123  LYS 123  141  141  LYS LYS A . n 
A 1 124  PRO 124  142  142  PRO PRO A . n 
A 1 125  LYS 125  143  143  LYS LYS A . n 
A 1 126  GLN 126  144  144  GLN GLN A . n 
A 1 127  GLU 127  145  145  GLU GLU A . n 
A 1 128  VAL 128  146  146  VAL VAL A . n 
A 1 129  LYS 129  147  147  LYS LYS A . n 
A 1 130  PHE 130  148  148  PHE PHE A . n 
A 1 131  ARG 131  149  149  ARG ARG A . n 
A 1 132  ILE 132  150  150  ILE ILE A . n 
A 1 133  VAL 133  151  151  VAL VAL A . n 
A 1 134  THR 134  152  152  THR THR A . n 
A 1 135  LEU 135  153  153  LEU LEU A . n 
A 1 136  PHE 136  154  154  PHE PHE A . n 
A 1 137  SER 137  155  155  SER SER A . n 
A 1 138  ASP 138  156  156  ASP ASP A . n 
A 1 139  PHE 139  157  157  PHE PHE A . n 
A 1 140  LYS 140  158  158  LYS LYS A . n 
A 1 141  PRO 141  159  159  PRO PRO A . n 
A 1 142  TYR 142  160  160  TYR TYR A . n 
A 1 143  LYS 143  161  161  LYS LYS A . n 
A 1 144  THR 144  162  162  THR THR A . n 
A 1 145  SER 145  163  163  SER SER A . n 
A 1 146  LEU 146  164  164  LEU LEU A . n 
A 1 147  ASN 147  165  165  ASN ASN A . n 
A 1 148  ILE 148  166  166  ILE ILE A . n 
A 1 149  LEU 149  167  167  LEU LEU A . n 
A 1 150  ILE 150  168  168  ILE ILE A . n 
A 1 151  LYS 151  169  169  LYS LYS A . n 
A 1 152  ASP 152  170  170  ASP ASP A . n 
A 1 153  PRO 153  171  171  PRO PRO A . n 
A 1 154  LYS 154  172  172  LYS LYS A . n 
A 1 155  SER 155  173  173  SER SER A . n 
A 1 156  ASN 156  174  174  ASN ASN A . n 
A 1 157  LEU 157  175  175  LEU LEU A . n 
A 1 158  ILE 158  176  176  ILE ILE A . n 
A 1 159  GLN 159  177  177  GLN GLN A . n 
A 1 160  GLN 160  178  178  GLN GLN A . n 
A 1 161  TRP 161  179  179  TRP TRP A . n 
A 1 162  LEU 162  180  180  LEU LEU A . n 
A 1 163  SER 163  181  181  SER SER A . n 
A 1 164  GLN 164  182  182  GLN GLN A . n 
A 1 165  GLN 165  183  183  GLN GLN A . n 
A 1 166  SER 166  184  184  SER SER A . n 
A 1 167  ASP 167  185  185  ASP ASP A . n 
A 1 168  LEU 168  186  186  LEU LEU A . n 
A 1 169  GLY 169  187  187  GLY GLY A . n 
A 1 170  VAL 170  188  188  VAL VAL A . n 
A 1 171  ILE 171  189  189  ILE ILE A . n 
A 1 172  SER 172  190  190  SER SER A . n 
A 1 173  LYS 173  191  191  LYS LYS A . n 
A 1 174  THR 174  192  192  THR THR A . n 
A 1 175  PHE 175  193  193  PHE PHE A . n 
A 1 176  GLN 176  194  194  GLN GLN A . n 
A 1 177  LEU 177  195  195  LEU LEU A . n 
A 1 178  SER 178  196  196  SER SER A . n 
A 1 179  SER 179  197  197  SER SER A . n 
A 1 180  HIS 180  198  198  HIS HIS A . n 
A 1 181  PRO 181  199  199  PRO PRO A . n 
A 1 182  ILE 182  200  200  ILE ILE A . n 
A 1 183  LEU 183  201  201  LEU LEU A . n 
A 1 184  GLY 184  202  202  GLY GLY A . n 
A 1 185  ASP 185  203  203  ASP ASP A . n 
A 1 186  TRP 186  204  204  TRP TRP A . n 
A 1 187  SER 187  205  205  SER SER A . n 
A 1 188  ILE 188  206  206  ILE ILE A . n 
A 1 189  GLN 189  207  207  GLN GLN A . n 
A 1 190  VAL 190  208  208  VAL VAL A . n 
A 1 191  GLN 191  209  209  GLN GLN A . n 
A 1 192  VAL 192  210  210  VAL VAL A . n 
A 1 193  ASN 193  211  211  ASN ASN A . n 
A 1 194  ASP 194  212  212  ASP ASP A . n 
A 1 195  GLN 195  213  213  GLN GLN A . n 
A 1 196  THR 196  214  214  THR THR A . n 
A 1 197  TYR 197  215  215  TYR TYR A . n 
A 1 198  TYR 198  216  216  TYR TYR A . n 
A 1 199  GLN 199  217  217  GLN GLN A . n 
A 1 200  SER 200  218  218  SER SER A . n 
A 1 201  PHE 201  219  219  PHE PHE A . n 
A 1 202  GLN 202  220  220  GLN GLN A . n 
A 1 203  VAL 203  221  221  VAL VAL A . n 
A 1 204  SER 204  222  222  SER SER A . n 
A 1 205  GLU 205  223  223  GLU GLU A . n 
A 1 206  TYR 206  224  224  TYR TYR A . n 
A 1 207  VAL 207  225  225  VAL VAL A . n 
A 1 208  LEU 208  226  226  LEU LEU A . n 
A 1 209  PRO 209  227  227  PRO PRO A . n 
A 1 210  LYS 210  228  228  LYS LYS A . n 
A 1 211  PHE 211  229  229  PHE PHE A . n 
A 1 212  GLU 212  230  230  GLU GLU A . n 
A 1 213  VAL 213  231  231  VAL VAL A . n 
A 1 214  THR 214  232  232  THR THR A . n 
A 1 215  LEU 215  233  233  LEU LEU A . n 
A 1 216  GLN 216  234  234  GLN GLN A . n 
A 1 217  THR 217  235  235  THR THR A . n 
A 1 218  PRO 218  236  236  PRO PRO A . n 
A 1 219  LEU 219  237  237  LEU LEU A . n 
A 1 220  TYR 220  238  238  TYR TYR A . n 
A 1 221  CYS 221  239  239  CYS CYS A . n 
A 1 222  SER 222  240  240  SER SER A . n 
A 1 223  MET 223  241  241  MET MET A . n 
A 1 224  ASN 224  242  242  ASN ASN A . n 
A 1 225  SER 225  243  243  SER SER A . n 
A 1 226  LYS 226  244  244  LYS LYS A . n 
A 1 227  HIS 227  245  245  HIS HIS A . n 
A 1 228  LEU 228  246  246  LEU LEU A . n 
A 1 229  ASN 229  247  247  ASN ASN A . n 
A 1 230  GLY 230  248  248  GLY GLY A . n 
A 1 231  THR 231  249  249  THR THR A . n 
A 1 232  ILE 232  250  250  ILE ILE A . n 
A 1 233  THR 233  251  251  THR THR A . n 
A 1 234  ALA 234  252  252  ALA ALA A . n 
A 1 235  LYS 235  253  253  LYS LYS A . n 
A 1 236  TYR 236  254  254  TYR TYR A . n 
A 1 237  THR 237  255  255  THR THR A . n 
A 1 238  TYR 238  256  256  TYR TYR A . n 
A 1 239  GLY 239  257  257  GLY GLY A . n 
A 1 240  LYS 240  258  258  LYS LYS A . n 
A 1 241  PRO 241  259  259  PRO PRO A . n 
A 1 242  VAL 242  260  260  VAL VAL A . n 
A 1 243  LYS 243  261  261  LYS LYS A . n 
A 1 244  GLY 244  262  262  GLY GLY A . n 
A 1 245  ASP 245  263  263  ASP ASP A . n 
A 1 246  VAL 246  264  264  VAL VAL A . n 
A 1 247  THR 247  265  265  THR THR A . n 
A 1 248  LEU 248  266  266  LEU LEU A . n 
A 1 249  THR 249  267  267  THR THR A . n 
A 1 250  PHE 250  268  268  PHE PHE A . n 
A 1 251  LEU 251  269  269  LEU LEU A . n 
A 1 252  PRO 252  270  270  PRO PRO A . n 
A 1 253  LEU 253  271  271  LEU LEU A . n 
A 1 254  SER 254  272  272  SER SER A . n 
A 1 255  PHE 255  273  273  PHE PHE A . n 
A 1 256  TRP 256  274  274  TRP TRP A . n 
A 1 257  GLY 257  275  275  GLY GLY A . n 
A 1 258  LYS 258  276  276  LYS LYS A . n 
A 1 259  LYS 259  277  277  LYS LYS A . n 
A 1 260  LYS 260  278  278  LYS LYS A . n 
A 1 261  ASN 261  279  279  ASN ASN A . n 
A 1 262  ILE 262  280  280  ILE ILE A . n 
A 1 263  THR 263  281  281  THR THR A . n 
A 1 264  LYS 264  282  282  LYS LYS A . n 
A 1 265  THR 265  283  283  THR THR A . n 
A 1 266  PHE 266  284  284  PHE PHE A . n 
A 1 267  LYS 267  285  285  LYS LYS A . n 
A 1 268  ILE 268  286  286  ILE ILE A . n 
A 1 269  ASN 269  287  287  ASN ASN A . n 
A 1 270  GLY 270  288  288  GLY GLY A . n 
A 1 271  SER 271  289  289  SER SER A . n 
A 1 272  ALA 272  290  290  ALA ALA A . n 
A 1 273  ASN 273  291  291  ASN ASN A . n 
A 1 274  PHE 274  292  292  PHE PHE A . n 
A 1 275  SER 275  293  293  SER SER A . n 
A 1 276  PHE 276  294  294  PHE PHE A . n 
A 1 277  ASN 277  295  295  ASN ASN A . n 
A 1 278  ASP 278  296  296  ASP ASP A . n 
A 1 279  GLU 279  297  297  GLU GLU A . n 
A 1 280  GLU 280  298  298  GLU GLU A . n 
A 1 281  MET 281  299  299  MET MET A . n 
A 1 282  LYS 282  300  300  LYS LYS A . n 
A 1 283  ASN 283  301  301  ASN ASN A . n 
A 1 284  VAL 284  302  302  VAL VAL A . n 
A 1 285  MET 285  303  303  MET MET A . n 
A 1 286  ASP 286  304  304  ASP ASP A . n 
A 1 287  SER 287  305  305  SER SER A . n 
A 1 288  SER 288  306  306  SER SER A . n 
A 1 289  ASN 289  307  ?    ?   ?   A . n 
A 1 290  GLY 290  308  ?    ?   ?   A . n 
A 1 291  LEU 291  309  ?    ?   ?   A . n 
A 1 292  SER 292  310  ?    ?   ?   A . n 
A 1 293  GLU 293  311  ?    ?   ?   A . n 
A 1 294  TYR 294  312  ?    ?   ?   A . n 
A 1 295  LEU 295  313  ?    ?   ?   A . n 
A 1 296  ASP 296  314  ?    ?   ?   A . n 
A 1 297  LEU 297  315  ?    ?   ?   A . n 
A 1 298  SER 298  316  316  SER SER A . n 
A 1 299  SER 299  317  317  SER SER A . n 
A 1 300  PRO 300  318  318  PRO PRO A . n 
A 1 301  GLY 301  319  319  GLY GLY A . n 
A 1 302  PRO 302  320  320  PRO PRO A . n 
A 1 303  VAL 303  321  321  VAL VAL A . n 
A 1 304  GLU 304  322  322  GLU GLU A . n 
A 1 305  ILE 305  323  323  ILE ILE A . n 
A 1 306  LEU 306  324  324  LEU LEU A . n 
A 1 307  THR 307  325  325  THR THR A . n 
A 1 308  THR 308  326  326  THR THR A . n 
A 1 309  VAL 309  327  327  VAL VAL A . n 
A 1 310  THR 310  328  328  THR THR A . n 
A 1 311  GLU 311  329  329  GLU GLU A . n 
A 1 312  SER 312  330  330  SER SER A . n 
A 1 313  VAL 313  331  331  VAL VAL A . n 
A 1 314  THR 314  332  332  THR THR A . n 
A 1 315  GLY 315  333  333  GLY GLY A . n 
A 1 316  ILE 316  334  334  ILE ILE A . n 
A 1 317  SER 317  335  335  SER SER A . n 
A 1 318  ARG 318  336  336  ARG ARG A . n 
A 1 319  ASN 319  337  337  ASN ASN A . n 
A 1 320  VAL 320  338  338  VAL VAL A . n 
A 1 321  SER 321  339  339  SER SER A . n 
A 1 322  THR 322  340  340  THR THR A . n 
A 1 323  ASN 323  341  341  ASN ASN A . n 
A 1 324  VAL 324  342  342  VAL VAL A . n 
A 1 325  PHE 325  343  343  PHE PHE A . n 
A 1 326  PHE 326  344  344  PHE PHE A . n 
A 1 327  LYS 327  345  345  LYS LYS A . n 
A 1 328  GLN 328  346  346  GLN GLN A . n 
A 1 329  HIS 329  347  347  HIS HIS A . n 
A 1 330  ASP 330  348  348  ASP ASP A . n 
A 1 331  TYR 331  349  349  TYR TYR A . n 
A 1 332  ILE 332  350  350  ILE ILE A . n 
A 1 333  ILE 333  351  351  ILE ILE A . n 
A 1 334  GLU 334  352  352  GLU GLU A . n 
A 1 335  PHE 335  353  353  PHE PHE A . n 
A 1 336  PHE 336  354  354  PHE PHE A . n 
A 1 337  ASP 337  355  355  ASP ASP A . n 
A 1 338  TYR 338  356  356  TYR TYR A . n 
A 1 339  THR 339  357  357  THR THR A . n 
A 1 340  THR 340  358  358  THR THR A . n 
A 1 341  VAL 341  359  359  VAL VAL A . n 
A 1 342  LEU 342  360  360  LEU LEU A . n 
A 1 343  LYS 343  361  361  LYS LYS A . n 
A 1 344  PRO 344  362  362  PRO PRO A . n 
A 1 345  SER 345  363  363  SER SER A . n 
A 1 346  LEU 346  364  364  LEU LEU A . n 
A 1 347  ASN 347  365  365  ASN ASN A . n 
A 1 348  PHE 348  366  366  PHE PHE A . n 
A 1 349  THR 349  367  367  THR THR A . n 
A 1 350  ALA 350  368  368  ALA ALA A . n 
A 1 351  THR 351  369  369  THR THR A . n 
A 1 352  VAL 352  370  370  VAL VAL A . n 
A 1 353  LYS 353  371  371  LYS LYS A . n 
A 1 354  VAL 354  372  372  VAL VAL A . n 
A 1 355  THR 355  373  373  THR THR A . n 
A 1 356  ARG 356  374  374  ARG ARG A . n 
A 1 357  ALA 357  375  375  ALA ALA A . n 
A 1 358  ASP 358  376  376  ASP ASP A . n 
A 1 359  GLY 359  377  377  GLY GLY A . n 
A 1 360  ASN 360  378  378  ASN ASN A . n 
A 1 361  GLN 361  379  379  GLN GLN A . n 
A 1 362  LEU 362  380  380  LEU LEU A . n 
A 1 363  THR 363  381  381  THR THR A . n 
A 1 364  LEU 364  382  382  LEU LEU A . n 
A 1 365  GLU 365  383  383  GLU GLU A . n 
A 1 366  GLU 366  384  384  GLU GLU A . n 
A 1 367  ARG 367  385  385  ARG ARG A . n 
A 1 368  ARG 368  386  386  ARG ARG A . n 
A 1 369  ASN 369  387  387  ASN ASN A . n 
A 1 370  ASN 370  388  388  ASN ASN A . n 
A 1 371  VAL 371  389  389  VAL VAL A . n 
A 1 372  VAL 372  390  390  VAL VAL A . n 
A 1 373  ILE 373  391  391  ILE ILE A . n 
A 1 374  THR 374  392  392  THR THR A . n 
A 1 375  VAL 375  393  393  VAL VAL A . n 
A 1 376  THR 376  394  394  THR THR A . n 
A 1 377  GLN 377  395  395  GLN GLN A . n 
A 1 378  ARG 378  396  396  ARG ARG A . n 
A 1 379  ASN 379  397  397  ASN ASN A . n 
A 1 380  TYR 380  398  398  TYR TYR A . n 
A 1 381  THR 381  399  ?    ?   ?   A . n 
A 1 382  GLU 382  400  ?    ?   ?   A . n 
A 1 383  TYR 383  401  ?    ?   ?   A . n 
A 1 384  TRP 384  402  ?    ?   ?   A . n 
A 1 385  SER 385  403  ?    ?   ?   A . n 
A 1 386  GLY 386  404  ?    ?   ?   A . n 
A 1 387  SER 387  405  ?    ?   ?   A . n 
A 1 388  ASN 388  406  ?    ?   ?   A . n 
A 1 389  SER 389  407  ?    ?   ?   A . n 
A 1 390  GLY 390  408  ?    ?   ?   A . n 
A 1 391  ASN 391  409  ?    ?   ?   A . n 
A 1 392  GLN 392  410  ?    ?   ?   A . n 
A 1 393  LYS 393  411  411  LYS LYS A . n 
A 1 394  MET 394  412  412  MET MET A . n 
A 1 395  GLU 395  413  413  GLU GLU A . n 
A 1 396  ALA 396  414  414  ALA ALA A . n 
A 1 397  VAL 397  415  415  VAL VAL A . n 
A 1 398  GLN 398  416  416  GLN GLN A . n 
A 1 399  LYS 399  417  417  LYS LYS A . n 
A 1 400  ILE 400  418  418  ILE ILE A . n 
A 1 401  ASN 401  419  419  ASN ASN A . n 
A 1 402  TYR 402  420  420  TYR TYR A . n 
A 1 403  THR 403  421  421  THR THR A . n 
A 1 404  VAL 404  422  422  VAL VAL A . n 
A 1 405  PRO 405  423  423  PRO PRO A . n 
A 1 406  GLN 406  424  424  GLN GLN A . n 
A 1 407  SER 407  425  425  SER SER A . n 
A 1 408  GLY 408  426  426  GLY GLY A . n 
A 1 409  THR 409  427  427  THR THR A . n 
A 1 410  PHE 410  428  428  PHE PHE A . n 
A 1 411  LYS 411  429  429  LYS LYS A . n 
A 1 412  ILE 412  430  430  ILE ILE A . n 
A 1 413  GLU 413  431  431  GLU GLU A . n 
A 1 414  PHE 414  432  432  PHE PHE A . n 
A 1 415  PRO 415  433  433  PRO PRO A . n 
A 1 416  ILE 416  434  434  ILE ILE A . n 
A 1 417  LEU 417  435  435  LEU LEU A . n 
A 1 418  GLU 418  436  436  GLU GLU A . n 
A 1 419  ASP 419  437  437  ASP ASP A . n 
A 1 420  SER 420  438  438  SER SER A . n 
A 1 421  SER 421  439  439  SER SER A . n 
A 1 422  GLU 422  440  440  GLU GLU A . n 
A 1 423  LEU 423  441  441  LEU LEU A . n 
A 1 424  GLN 424  442  442  GLN GLN A . n 
A 1 425  LEU 425  443  443  LEU LEU A . n 
A 1 426  LYS 426  444  444  LYS LYS A . n 
A 1 427  ALA 427  445  445  ALA ALA A . n 
A 1 428  TYR 428  446  446  TYR TYR A . n 
A 1 429  PHE 429  447  447  PHE PHE A . n 
A 1 430  LEU 430  448  448  LEU LEU A . n 
A 1 431  GLY 431  449  449  GLY GLY A . n 
A 1 432  SER 432  450  450  SER SER A . n 
A 1 433  LYS 433  451  451  LYS LYS A . n 
A 1 434  SER 434  452  452  SER SER A . n 
A 1 435  SER 435  453  453  SER SER A . n 
A 1 436  MET 436  454  454  MET MET A . n 
A 1 437  ALA 437  455  455  ALA ALA A . n 
A 1 438  VAL 438  456  456  VAL VAL A . n 
A 1 439  HIS 439  457  457  HIS HIS A . n 
A 1 440  SER 440  458  458  SER SER A . n 
A 1 441  LEU 441  459  459  LEU LEU A . n 
A 1 442  PHE 442  460  460  PHE PHE A . n 
A 1 443  LYS 443  461  461  LYS LYS A . n 
A 1 444  SER 444  462  462  SER SER A . n 
A 1 445  PRO 445  463  463  PRO PRO A . n 
A 1 446  SER 446  464  464  SER SER A . n 
A 1 447  LYS 447  465  465  LYS LYS A . n 
A 1 448  THR 448  466  466  THR THR A . n 
A 1 449  TYR 449  467  467  TYR TYR A . n 
A 1 450  ILE 450  468  468  ILE ILE A . n 
A 1 451  GLN 451  469  469  GLN GLN A . n 
A 1 452  LEU 452  470  470  LEU LEU A . n 
A 1 453  LYS 453  471  471  LYS LYS A . n 
A 1 454  THR 454  472  472  THR THR A . n 
A 1 455  ARG 455  473  473  ARG ARG A . n 
A 1 456  ASP 456  474  474  ASP ASP A . n 
A 1 457  GLU 457  475  475  GLU GLU A . n 
A 1 458  ASN 458  476  476  ASN ASN A . n 
A 1 459  ILE 459  477  477  ILE ILE A . n 
A 1 460  LYS 460  478  478  LYS LYS A . n 
A 1 461  VAL 461  479  479  VAL VAL A . n 
A 1 462  GLY 462  480  480  GLY GLY A . n 
A 1 463  SER 463  481  481  SER SER A . n 
A 1 464  PRO 464  482  482  PRO PRO A . n 
A 1 465  PHE 465  483  483  PHE PHE A . n 
A 1 466  GLU 466  484  484  GLU GLU A . n 
A 1 467  LEU 467  485  485  LEU LEU A . n 
A 1 468  VAL 468  486  486  VAL VAL A . n 
A 1 469  VAL 469  487  487  VAL VAL A . n 
A 1 470  SER 470  488  488  SER SER A . n 
A 1 471  GLY 471  489  489  GLY GLY A . n 
A 1 472  ASN 472  490  490  ASN ASN A . n 
A 1 473  LYS 473  491  491  LYS LYS A . n 
A 1 474  ARG 474  492  492  ARG ARG A . n 
A 1 475  LEU 475  493  493  LEU LEU A . n 
A 1 476  LYS 476  494  494  LYS LYS A . n 
A 1 477  GLU 477  495  495  GLU GLU A . n 
A 1 478  LEU 478  496  496  LEU LEU A . n 
A 1 479  SER 479  497  497  SER SER A . n 
A 1 480  TYR 480  498  498  TYR TYR A . n 
A 1 481  MET 481  499  499  MET MET A . n 
A 1 482  VAL 482  500  500  VAL VAL A . n 
A 1 483  VAL 483  501  501  VAL VAL A . n 
A 1 484  SER 484  502  502  SER SER A . n 
A 1 485  ARG 485  503  503  ARG ARG A . n 
A 1 486  GLY 486  504  504  GLY GLY A . n 
A 1 487  GLN 487  505  505  GLN GLN A . n 
A 1 488  LEU 488  506  506  LEU LEU A . n 
A 1 489  VAL 489  507  507  VAL VAL A . n 
A 1 490  ALA 490  508  508  ALA ALA A . n 
A 1 491  VAL 491  509  509  VAL VAL A . n 
A 1 492  GLY 492  510  510  GLY GLY A . n 
A 1 493  LYS 493  511  511  LYS LYS A . n 
A 1 494  GLN 494  512  512  GLN GLN A . n 
A 1 495  ASN 495  513  513  ASN ASN A . n 
A 1 496  SER 496  514  514  SER SER A . n 
A 1 497  THR 497  515  515  THR THR A . n 
A 1 498  MET 498  516  516  MET MET A . n 
A 1 499  PHE 499  517  517  PHE PHE A . n 
A 1 500  SER 500  518  518  SER SER A . n 
A 1 501  LEU 501  519  519  LEU LEU A . n 
A 1 502  THR 502  520  520  THR THR A . n 
A 1 503  PRO 503  521  521  PRO PRO A . n 
A 1 504  GLU 504  522  522  GLU GLU A . n 
A 1 505  ASN 505  523  523  ASN ASN A . n 
A 1 506  SER 506  524  524  SER SER A . n 
A 1 507  TRP 507  525  525  TRP TRP A . n 
A 1 508  THR 508  526  526  THR THR A . n 
A 1 509  PRO 509  527  527  PRO PRO A . n 
A 1 510  LYS 510  528  528  LYS LYS A . n 
A 1 511  ALA 511  529  529  ALA ALA A . n 
A 1 512  CYS 512  530  530  CYS CYS A . n 
A 1 513  VAL 513  531  531  VAL VAL A . n 
A 1 514  ILE 514  532  532  ILE ILE A . n 
A 1 515  VAL 515  533  533  VAL VAL A . n 
A 1 516  TYR 516  534  534  TYR TYR A . n 
A 1 517  TYR 517  535  535  TYR TYR A . n 
A 1 518  ILE 518  536  536  ILE ILE A . n 
A 1 519  GLU 519  537  537  GLU GLU A . n 
A 1 520  ASP 520  538  538  ASP ASP A . n 
A 1 521  ASP 521  539  539  ASP ASP A . n 
A 1 522  GLY 522  540  540  GLY GLY A . n 
A 1 523  GLU 523  541  541  GLU GLU A . n 
A 1 524  ILE 524  542  542  ILE ILE A . n 
A 1 525  ILE 525  543  543  ILE ILE A . n 
A 1 526  SER 526  544  544  SER SER A . n 
A 1 527  ASP 527  545  545  ASP ASP A . n 
A 1 528  VAL 528  546  546  VAL VAL A . n 
A 1 529  LEU 529  547  547  LEU LEU A . n 
A 1 530  LYS 530  548  548  LYS LYS A . n 
A 1 531  ILE 531  549  549  ILE ILE A . n 
A 1 532  PRO 532  550  550  PRO PRO A . n 
A 1 533  VAL 533  551  551  VAL VAL A . n 
A 1 534  GLN 534  552  552  GLN GLN A . n 
A 1 535  LEU 535  553  553  LEU LEU A . n 
A 1 536  VAL 536  554  554  VAL VAL A . n 
A 1 537  PHE 537  555  555  PHE PHE A . n 
A 1 538  LYS 538  556  556  LYS LYS A . n 
A 1 539  ASN 539  557  557  ASN ASN A . n 
A 1 540  LYS 540  558  558  LYS LYS A . n 
A 1 541  ILE 541  559  559  ILE ILE A . n 
A 1 542  LYS 542  560  560  LYS LYS A . n 
A 1 543  LEU 543  561  561  LEU LEU A . n 
A 1 544  TYR 544  562  562  TYR TYR A . n 
A 1 545  TRP 545  563  563  TRP TRP A . n 
A 1 546  SER 546  564  564  SER SER A . n 
A 1 547  LYS 547  565  565  LYS LYS A . n 
A 1 548  VAL 548  566  566  VAL VAL A . n 
A 1 549  LYS 549  567  567  LYS LYS A . n 
A 1 550  ALA 550  568  568  ALA ALA A . n 
A 1 551  GLU 551  569  569  GLU GLU A . n 
A 1 552  PRO 552  570  570  PRO PRO A . n 
A 1 553  SER 553  571  571  SER SER A . n 
A 1 554  GLU 554  572  572  GLU GLU A . n 
A 1 555  LYS 555  573  573  LYS LYS A . n 
A 1 556  VAL 556  574  574  VAL VAL A . n 
A 1 557  SER 557  575  575  SER SER A . n 
A 1 558  LEU 558  576  576  LEU LEU A . n 
A 1 559  ARG 559  577  577  ARG ARG A . n 
A 1 560  ILE 560  578  578  ILE ILE A . n 
A 1 561  SER 561  579  579  SER SER A . n 
A 1 562  VAL 562  580  580  VAL VAL A . n 
A 1 563  THR 563  581  581  THR THR A . n 
A 1 564  GLN 564  582  582  GLN GLN A . n 
A 1 565  PRO 565  583  583  PRO PRO A . n 
A 1 566  ASP 566  584  584  ASP ASP A . n 
A 1 567  SER 567  585  585  SER SER A . n 
A 1 568  ILE 568  586  586  ILE ILE A . n 
A 1 569  VAL 569  587  587  VAL VAL A . n 
A 1 570  GLY 570  588  588  GLY GLY A . n 
A 1 571  ILE 571  589  589  ILE ILE A . n 
A 1 572  VAL 572  590  590  VAL VAL A . n 
A 1 573  ALA 573  591  591  ALA ALA A . n 
A 1 574  VAL 574  592  592  VAL VAL A . n 
A 1 575  ASP 575  593  593  ASP ASP A . n 
A 1 576  LYS 576  594  594  LYS LYS A . n 
A 1 577  SER 577  595  595  SER SER A . n 
A 1 578  VAL 578  596  596  VAL VAL A . n 
A 1 579  ASN 579  597  597  ASN ASN A . n 
A 1 580  LEU 580  598  598  LEU LEU A . n 
A 1 581  MET 581  599  599  MET MET A . n 
A 1 582  ASN 582  600  600  ASN ASN A . n 
A 1 583  ALA 583  601  601  ALA ALA A . n 
A 1 584  SER 584  602  602  SER SER A . n 
A 1 585  ASN 585  603  603  ASN ASN A . n 
A 1 586  ASP 586  604  604  ASP ASP A . n 
A 1 587  ILE 587  605  605  ILE ILE A . n 
A 1 588  THR 588  606  606  THR THR A . n 
A 1 589  MET 589  607  607  MET MET A . n 
A 1 590  GLU 590  608  608  GLU GLU A . n 
A 1 591  ASN 591  609  609  ASN ASN A . n 
A 1 592  VAL 592  610  610  VAL VAL A . n 
A 1 593  VAL 593  611  611  VAL VAL A . n 
A 1 594  HIS 594  612  612  HIS HIS A . n 
A 1 595  GLU 595  613  613  GLU GLU A . n 
A 1 596  LEU 596  614  614  LEU LEU A . n 
A 1 597  GLU 597  615  615  GLU GLU A . n 
A 1 598  LEU 598  616  616  LEU LEU A . n 
A 1 599  TYR 599  617  617  TYR TYR A . n 
A 1 600  ASN 600  618  618  ASN ASN A . n 
A 1 601  THR 601  619  619  THR THR A . n 
A 1 602  GLY 602  620  620  GLY GLY A . n 
A 1 603  TYR 603  621  621  TYR TYR A . n 
A 1 604  TYR 604  622  622  TYR TYR A . n 
A 1 605  LEU 605  623  623  LEU LEU A . n 
A 1 606  GLY 606  624  624  GLY GLY A . n 
A 1 607  MET 607  625  625  MET MET A . n 
A 1 608  PHE 608  626  626  PHE PHE A . n 
A 1 609  MET 609  627  627  MET MET A . n 
A 1 610  ASN 610  628  628  ASN ASN A . n 
A 1 611  SER 611  629  629  SER SER A . n 
A 1 612  PHE 612  630  630  PHE PHE A . n 
A 1 613  ALA 613  631  631  ALA ALA A . n 
A 1 614  VAL 614  632  632  VAL VAL A . n 
A 1 615  PHE 615  633  633  PHE PHE A . n 
A 1 616  GLN 616  634  634  GLN GLN A . n 
A 1 617  GLU 617  635  635  GLU GLU A . n 
A 1 618  CYS 618  636  636  CYS CYS A . n 
A 1 619  GLY 619  637  637  GLY GLY A . n 
A 1 620  LEU 620  638  638  LEU LEU A . n 
A 1 621  TRP 621  639  639  TRP TRP A . n 
A 1 622  VAL 622  640  640  VAL VAL A . n 
A 1 623  LEU 623  641  641  LEU LEU A . n 
A 1 624  THR 624  642  642  THR THR A . n 
A 1 625  ASP 625  643  643  ASP ASP A . n 
A 1 626  ALA 626  644  644  ALA ALA A . n 
A 1 627  ASN 627  645  645  ASN ASN A . n 
A 1 628  LEU 628  646  646  LEU LEU A . n 
A 1 629  THR 629  647  647  THR THR A . n 
A 1 630  LYS 630  648  ?    ?   ?   A . n 
A 1 631  ASP 631  649  ?    ?   ?   A . n 
A 1 632  TYR 632  650  ?    ?   ?   A . n 
A 1 633  ILE 633  651  ?    ?   ?   A . n 
A 1 634  ASP 634  652  ?    ?   ?   A . n 
A 1 635  GLY 635  653  ?    ?   ?   A . n 
A 1 636  VAL 636  654  ?    ?   ?   A . n 
A 1 637  TYR 637  655  ?    ?   ?   A . n 
A 1 638  ASP 638  656  ?    ?   ?   A . n 
A 1 639  ASN 639  657  ?    ?   ?   A . n 
A 1 640  ALA 640  658  ?    ?   ?   A . n 
A 1 641  GLU 641  659  ?    ?   ?   A . n 
A 1 642  TYR 642  660  ?    ?   ?   A . n 
A 1 643  ALA 643  661  ?    ?   ?   A . n 
A 1 644  GLU 644  662  ?    ?   ?   A . n 
A 1 645  ARG 645  663  ?    ?   ?   A . n 
A 1 646  GLU 646  664  ?    ?   ?   A . n 
A 1 647  ASN 647  665  ?    ?   ?   A . n 
A 1 648  LEU 648  666  ?    ?   ?   A . n 
A 1 649  TYR 649  667  ?    ?   ?   A . n 
A 1 650  PHE 650  668  ?    ?   ?   A . n 
A 1 651  GLN 651  669  ?    ?   ?   A . n 
A 1 652  GLY 652  670  ?    ?   ?   A . n 
A 1 653  HIS 653  671  ?    ?   ?   A . n 
A 1 654  ILE 654  672  ?    ?   ?   A . n 
A 1 655  VAL 655  673  ?    ?   ?   A . n 
A 1 656  ASP 656  674  ?    ?   ?   A . n 
A 1 657  ILE 657  675  ?    ?   ?   A . n 
A 1 658  HIS 658  676  ?    ?   ?   A . n 
A 1 659  ASP 659  677  ?    ?   ?   A . n 
A 1 660  PHE 660  678  ?    ?   ?   A . n 
A 1 661  SER 661  679  ?    ?   ?   A . n 
A 1 662  LEU 662  680  ?    ?   ?   A . n 
A 1 663  GLY 663  681  ?    ?   ?   A . n 
A 1 664  SER 664  682  ?    ?   ?   A . n 
A 1 665  SER 665  683  ?    ?   ?   A . n 
A 1 666  PRO 666  684  ?    ?   ?   A . n 
A 1 667  HIS 667  685  ?    ?   ?   A . n 
A 1 668  VAL 668  686  ?    ?   ?   A . n 
A 1 669  ARG 669  687  ?    ?   ?   A . n 
A 1 670  LYS 670  688  ?    ?   ?   A . n 
A 1 671  HIS 671  689  689  HIS HIS A . n 
A 1 672  PHE 672  690  690  PHE PHE A . n 
A 1 673  PRO 673  691  691  PRO PRO A . n 
A 1 674  GLU 674  692  692  GLU GLU A . n 
A 1 675  THR 675  693  693  THR THR A . n 
A 1 676  TRP 676  694  694  TRP TRP A . n 
A 1 677  ILE 677  695  695  ILE ILE A . n 
A 1 678  TRP 678  696  696  TRP TRP A . n 
A 1 679  LEU 679  697  697  LEU LEU A . n 
A 1 680  ASP 680  698  698  ASP ASP A . n 
A 1 681  THR 681  699  699  THR THR A . n 
A 1 682  ASN 682  700  700  ASN ASN A . n 
A 1 683  MET 683  701  701  MET MET A . n 
A 1 684  GLY 684  702  702  GLY GLY A . n 
A 1 685  TYR 685  703  703  TYR TYR A . n 
A 1 686  ARG 686  704  704  ARG ARG A . n 
A 1 687  ILE 687  705  705  ILE ILE A . n 
A 1 688  TYR 688  706  706  TYR TYR A . n 
A 1 689  GLN 689  707  707  GLN GLN A . n 
A 1 690  GLU 690  708  708  GLU GLU A . n 
A 1 691  PHE 691  709  709  PHE PHE A . n 
A 1 692  GLU 692  710  710  GLU GLU A . n 
A 1 693  VAL 693  711  711  VAL VAL A . n 
A 1 694  THR 694  712  712  THR THR A . n 
A 1 695  VAL 695  713  713  VAL VAL A . n 
A 1 696  PRO 696  714  714  PRO PRO A . n 
A 1 697  ASP 697  715  715  ASP ASP A . n 
A 1 698  SER 698  716  716  SER SER A . n 
A 1 699  ILE 699  717  717  ILE ILE A . n 
A 1 700  THR 700  718  718  THR THR A . n 
A 1 701  SER 701  719  719  SER SER A . n 
A 1 702  TRP 702  720  720  TRP TRP A . n 
A 1 703  VAL 703  721  721  VAL VAL A . n 
A 1 704  ALA 704  722  722  ALA ALA A . n 
A 1 705  THR 705  723  723  THR THR A . n 
A 1 706  GLY 706  724  724  GLY GLY A . n 
A 1 707  PHE 707  725  725  PHE PHE A . n 
A 1 708  VAL 708  726  726  VAL VAL A . n 
A 1 709  ILE 709  727  727  ILE ILE A . n 
A 1 710  SER 710  728  728  SER SER A . n 
A 1 711  GLU 711  729  729  GLU GLU A . n 
A 1 712  ASP 712  730  730  ASP ASP A . n 
A 1 713  LEU 713  731  731  LEU LEU A . n 
A 1 714  GLY 714  732  732  GLY GLY A . n 
A 1 715  LEU 715  733  733  LEU LEU A . n 
A 1 716  GLY 716  734  734  GLY GLY A . n 
A 1 717  LEU 717  735  735  LEU LEU A . n 
A 1 718  THR 718  736  736  THR THR A . n 
A 1 719  THR 719  737  737  THR THR A . n 
A 1 720  THR 720  738  738  THR THR A . n 
A 1 721  PRO 721  739  739  PRO PRO A . n 
A 1 722  VAL 722  740  740  VAL VAL A . n 
A 1 723  GLU 723  741  741  GLU GLU A . n 
A 1 724  LEU 724  742  742  LEU LEU A . n 
A 1 725  GLN 725  743  743  GLN GLN A . n 
A 1 726  ALA 726  744  744  ALA ALA A . n 
A 1 727  PHE 727  745  745  PHE PHE A . n 
A 1 728  GLN 728  746  746  GLN GLN A . n 
A 1 729  PRO 729  747  747  PRO PRO A . n 
A 1 730  PHE 730  748  748  PHE PHE A . n 
A 1 731  PHE 731  749  749  PHE PHE A . n 
A 1 732  ILE 732  750  750  ILE ILE A . n 
A 1 733  PHE 733  751  751  PHE PHE A . n 
A 1 734  LEU 734  752  752  LEU LEU A . n 
A 1 735  ASN 735  753  753  ASN ASN A . n 
A 1 736  LEU 736  754  754  LEU LEU A . n 
A 1 737  PRO 737  755  755  PRO PRO A . n 
A 1 738  TYR 738  756  756  TYR TYR A . n 
A 1 739  SER 739  757  757  SER SER A . n 
A 1 740  VAL 740  758  758  VAL VAL A . n 
A 1 741  ILE 741  759  759  ILE ILE A . n 
A 1 742  ARG 742  760  760  ARG ARG A . n 
A 1 743  GLY 743  761  761  GLY GLY A . n 
A 1 744  GLU 744  762  762  GLU GLU A . n 
A 1 745  GLU 745  763  763  GLU GLU A . n 
A 1 746  PHE 746  764  764  PHE PHE A . n 
A 1 747  ALA 747  765  765  ALA ALA A . n 
A 1 748  LEU 748  766  766  LEU LEU A . n 
A 1 749  GLU 749  767  767  GLU GLU A . n 
A 1 750  ILE 750  768  768  ILE ILE A . n 
A 1 751  THR 751  769  769  THR THR A . n 
A 1 752  ILE 752  770  770  ILE ILE A . n 
A 1 753  PHE 753  771  771  PHE PHE A . n 
A 1 754  ASN 754  772  772  ASN ASN A . n 
A 1 755  TYR 755  773  773  TYR TYR A . n 
A 1 756  LEU 756  774  774  LEU LEU A . n 
A 1 757  LYS 757  775  775  LYS LYS A . n 
A 1 758  ASP 758  776  776  ASP ASP A . n 
A 1 759  ALA 759  777  777  ALA ALA A . n 
A 1 760  THR 760  778  778  THR THR A . n 
A 1 761  GLU 761  779  779  GLU GLU A . n 
A 1 762  VAL 762  780  780  VAL VAL A . n 
A 1 763  LYS 763  781  781  LYS LYS A . n 
A 1 764  VAL 764  782  782  VAL VAL A . n 
A 1 765  ILE 765  783  783  ILE ILE A . n 
A 1 766  ILE 766  784  784  ILE ILE A . n 
A 1 767  GLU 767  785  785  GLU GLU A . n 
A 1 768  LYS 768  786  786  LYS LYS A . n 
A 1 769  SER 769  787  787  SER SER A . n 
A 1 770  ASP 770  788  788  ASP ASP A . n 
A 1 771  LYS 771  789  789  LYS LYS A . n 
A 1 772  PHE 772  790  790  PHE PHE A . n 
A 1 773  ASP 773  791  791  ASP ASP A . n 
A 1 774  ILE 774  792  792  ILE ILE A . n 
A 1 775  LEU 775  793  793  LEU LEU A . n 
A 1 776  MET 776  794  794  MET MET A . n 
A 1 777  THR 777  795  795  THR THR A . n 
A 1 778  SER 778  796  796  SER SER A . n 
A 1 779  ASN 779  797  797  ASN ASN A . n 
A 1 780  GLU 780  798  798  GLU GLU A . n 
A 1 781  ILE 781  799  799  ILE ILE A . n 
A 1 782  ASN 782  800  800  ASN ASN A . n 
A 1 783  ALA 783  801  801  ALA ALA A . n 
A 1 784  THR 784  802  802  THR THR A . n 
A 1 785  GLY 785  803  803  GLY GLY A . n 
A 1 786  HIS 786  804  804  HIS HIS A . n 
A 1 787  GLN 787  805  805  GLN GLN A . n 
A 1 788  GLN 788  806  806  GLN GLN A . n 
A 1 789  THR 789  807  807  THR THR A . n 
A 1 790  LEU 790  808  808  LEU LEU A . n 
A 1 791  LEU 791  809  809  LEU LEU A . n 
A 1 792  VAL 792  810  810  VAL VAL A . n 
A 1 793  PRO 793  811  811  PRO PRO A . n 
A 1 794  SER 794  812  812  SER SER A . n 
A 1 795  GLU 795  813  813  GLU GLU A . n 
A 1 796  ASP 796  814  814  ASP ASP A . n 
A 1 797  GLY 797  815  815  GLY GLY A . n 
A 1 798  ALA 798  816  816  ALA ALA A . n 
A 1 799  THR 799  817  817  THR THR A . n 
A 1 800  VAL 800  818  818  VAL VAL A . n 
A 1 801  LEU 801  819  819  LEU LEU A . n 
A 1 802  PHE 802  820  820  PHE PHE A . n 
A 1 803  PRO 803  821  821  PRO PRO A . n 
A 1 804  ILE 804  822  822  ILE ILE A . n 
A 1 805  ARG 805  823  823  ARG ARG A . n 
A 1 806  PRO 806  824  824  PRO PRO A . n 
A 1 807  THR 807  825  825  THR THR A . n 
A 1 808  HIS 808  826  826  HIS HIS A . n 
A 1 809  LEU 809  827  827  LEU LEU A . n 
A 1 810  GLY 810  828  828  GLY GLY A . n 
A 1 811  GLU 811  829  829  GLU GLU A . n 
A 1 812  ILE 812  830  830  ILE ILE A . n 
A 1 813  PRO 813  831  831  PRO PRO A . n 
A 1 814  ILE 814  832  832  ILE ILE A . n 
A 1 815  THR 815  833  833  THR THR A . n 
A 1 816  VAL 816  834  834  VAL VAL A . n 
A 1 817  THR 817  835  835  THR THR A . n 
A 1 818  ALA 818  836  836  ALA ALA A . n 
A 1 819  LEU 819  837  837  LEU LEU A . n 
A 1 820  SER 820  838  838  SER SER A . n 
A 1 821  PRO 821  839  839  PRO PRO A . n 
A 1 822  THR 822  840  840  THR THR A . n 
A 1 823  ALA 823  841  841  ALA ALA A . n 
A 1 824  SER 824  842  842  SER SER A . n 
A 1 825  ASP 825  843  843  ASP ASP A . n 
A 1 826  ALA 826  844  844  ALA ALA A . n 
A 1 827  VAL 827  845  845  VAL VAL A . n 
A 1 828  THR 828  846  846  THR THR A . n 
A 1 829  GLN 829  847  847  GLN GLN A . n 
A 1 830  MET 830  848  848  MET MET A . n 
A 1 831  ILE 831  849  849  ILE ILE A . n 
A 1 832  LEU 832  850  850  LEU LEU A . n 
A 1 833  VAL 833  851  851  VAL VAL A . n 
A 1 834  LYS 834  852  852  LYS LYS A . n 
A 1 835  ALA 835  853  853  ALA ALA A . n 
A 1 836  GLU 836  854  854  GLU GLU A . n 
A 1 837  GLY 837  855  855  GLY GLY A . n 
A 1 838  ILE 838  856  856  ILE ILE A . n 
A 1 839  GLU 839  857  857  GLU GLU A . n 
A 1 840  LYS 840  858  858  LYS LYS A . n 
A 1 841  SER 841  859  859  SER SER A . n 
A 1 842  TYR 842  860  860  TYR TYR A . n 
A 1 843  SER 843  861  861  SER SER A . n 
A 1 844  GLN 844  862  862  GLN GLN A . n 
A 1 845  SER 845  863  863  SER SER A . n 
A 1 846  ILE 846  864  864  ILE ILE A . n 
A 1 847  LEU 847  865  865  LEU LEU A . n 
A 1 848  LEU 848  866  866  LEU LEU A . n 
A 1 849  ASP 849  867  867  ASP ASP A . n 
A 1 850  LEU 850  868  868  LEU LEU A . n 
A 1 851  THR 851  869  869  THR THR A . n 
A 1 852  ASP 852  870  870  ASP ASP A . n 
A 1 853  ASN 853  871  871  ASN ASN A . n 
A 1 854  ARG 854  872  872  ARG ARG A . n 
A 1 855  LEU 855  873  873  LEU LEU A . n 
A 1 856  GLN 856  874  874  GLN GLN A . n 
A 1 857  SER 857  875  875  SER SER A . n 
A 1 858  THR 858  876  876  THR THR A . n 
A 1 859  LEU 859  877  877  LEU LEU A . n 
A 1 860  LYS 860  878  878  LYS LYS A . n 
A 1 861  THR 861  879  879  THR THR A . n 
A 1 862  LEU 862  880  880  LEU LEU A . n 
A 1 863  SER 863  881  881  SER SER A . n 
A 1 864  PHE 864  882  882  PHE PHE A . n 
A 1 865  SER 865  883  883  SER SER A . n 
A 1 866  PHE 866  884  884  PHE PHE A . n 
A 1 867  PRO 867  885  885  PRO PRO A . n 
A 1 868  PRO 868  886  886  PRO PRO A . n 
A 1 869  ASN 869  887  887  ASN ASN A . n 
A 1 870  THR 870  888  888  THR THR A . n 
A 1 871  VAL 871  889  889  VAL VAL A . n 
A 1 872  THR 872  890  890  THR THR A . n 
A 1 873  GLY 873  891  891  GLY GLY A . n 
A 1 874  SER 874  892  892  SER SER A . n 
A 1 875  GLU 875  893  893  GLU GLU A . n 
A 1 876  ARG 876  894  894  ARG ARG A . n 
A 1 877  VAL 877  895  895  VAL VAL A . n 
A 1 878  GLN 878  896  896  GLN GLN A . n 
A 1 879  ILE 879  897  897  ILE ILE A . n 
A 1 880  THR 880  898  898  THR THR A . n 
A 1 881  ALA 881  899  899  ALA ALA A . n 
A 1 882  ILE 882  900  900  ILE ILE A . n 
A 1 883  GLY 883  901  901  GLY GLY A . n 
A 1 884  ASP 884  902  902  ASP ASP A . n 
A 1 885  VAL 885  903  903  VAL VAL A . n 
A 1 886  LEU 886  904  904  LEU LEU A . n 
A 1 887  GLY 887  905  905  GLY GLY A . n 
A 1 888  PRO 888  906  906  PRO PRO A . n 
A 1 889  SER 889  907  907  SER SER A . n 
A 1 890  ILE 890  908  908  ILE ILE A . n 
A 1 891  ASN 891  909  909  ASN ASN A . n 
A 1 892  GLY 892  910  910  GLY GLY A . n 
A 1 893  LEU 893  911  911  LEU LEU A . n 
A 1 894  ALA 894  912  912  ALA ALA A . n 
A 1 895  SER 895  913  913  SER SER A . n 
A 1 896  LEU 896  914  914  LEU LEU A . n 
A 1 897  ILE 897  915  915  ILE ILE A . n 
A 1 898  ARG 898  916  916  ARG ARG A . n 
A 1 899  MET 899  917  917  MET MET A . n 
A 1 900  PRO 900  918  918  PRO PRO A . n 
A 1 901  TYR 901  919  919  TYR TYR A . n 
A 1 902  GLY 902  920  920  GLY GLY A . n 
A 1 903  CYS 903  921  921  CYS CYS A . n 
A 1 904  GLY 904  922  922  GLY GLY A . n 
A 1 905  GLU 905  923  923  GLU GLU A . n 
A 1 906  GLN 906  924  924  GLN GLN A . n 
A 1 907  ASN 907  925  925  ASN ASN A . n 
A 1 908  MET 908  926  926  MET MET A . n 
A 1 909  ILE 909  927  927  ILE ILE A . n 
A 1 910  ASN 910  928  928  ASN ASN A . n 
A 1 911  PHE 911  929  929  PHE PHE A . n 
A 1 912  ALA 912  930  930  ALA ALA A . n 
A 1 913  PRO 913  931  931  PRO PRO A . n 
A 1 914  ASN 914  932  932  ASN ASN A . n 
A 1 915  ILE 915  933  933  ILE ILE A . n 
A 1 916  TYR 916  934  934  TYR TYR A . n 
A 1 917  ILE 917  935  935  ILE ILE A . n 
A 1 918  LEU 918  936  936  LEU LEU A . n 
A 1 919  ASP 919  937  937  ASP ASP A . n 
A 1 920  TYR 920  938  938  TYR TYR A . n 
A 1 921  LEU 921  939  939  LEU LEU A . n 
A 1 922  THR 922  940  940  THR THR A . n 
A 1 923  LYS 923  941  941  LYS LYS A . n 
A 1 924  LYS 924  942  942  LYS LYS A . n 
A 1 925  LYS 925  943  943  LYS LYS A . n 
A 1 926  GLN 926  944  944  GLN GLN A . n 
A 1 927  LEU 927  945  945  LEU LEU A . n 
A 1 928  THR 928  946  946  THR THR A . n 
A 1 929  ASP 929  947  947  ASP ASP A . n 
A 1 930  ASN 930  948  948  ASN ASN A . n 
A 1 931  LEU 931  949  949  LEU LEU A . n 
A 1 932  LYS 932  950  950  LYS LYS A . n 
A 1 933  GLU 933  951  951  GLU GLU A . n 
A 1 934  LYS 934  952  952  LYS LYS A . n 
A 1 935  ALA 935  953  953  ALA ALA A . n 
A 1 936  LEU 936  954  954  LEU LEU A . n 
A 1 937  SER 937  955  955  SER SER A . n 
A 1 938  PHE 938  956  956  PHE PHE A . n 
A 1 939  MET 939  957  957  MET MET A . n 
A 1 940  ARG 940  958  958  ARG ARG A . n 
A 1 941  GLN 941  959  959  GLN GLN A . n 
A 1 942  GLY 942  960  960  GLY GLY A . n 
A 1 943  TYR 943  961  961  TYR TYR A . n 
A 1 944  GLN 944  962  962  GLN GLN A . n 
A 1 945  ARG 945  963  963  ARG ARG A . n 
A 1 946  GLU 946  964  964  GLU GLU A . n 
A 1 947  LEU 947  965  965  LEU LEU A . n 
A 1 948  LEU 948  966  966  LEU LEU A . n 
A 1 949  TYR 949  967  967  TYR TYR A . n 
A 1 950  GLN 950  968  968  GLN GLN A . n 
A 1 951  ARG 951  969  969  ARG ARG A . n 
A 1 952  GLU 952  970  970  GLU GLU A . n 
A 1 953  ASP 953  971  971  ASP ASP A . n 
A 1 954  GLY 954  972  972  GLY GLY A . n 
A 1 955  SER 955  973  973  SER SER A . n 
A 1 956  PHE 956  974  974  PHE PHE A . n 
A 1 957  SER 957  975  975  SER SER A . n 
A 1 958  ALA 958  976  976  ALA ALA A . n 
A 1 959  PHE 959  977  977  PHE PHE A . n 
A 1 960  GLY 960  978  978  GLY GLY A . n 
A 1 961  ASN 961  979  979  ASN ASN A . n 
A 1 962  TYR 962  980  980  TYR TYR A . n 
A 1 963  ASP 963  981  981  ASP ASP A . n 
A 1 964  PRO 964  982  982  PRO PRO A . n 
A 1 965  SER 965  983  983  SER SER A . n 
A 1 966  GLY 966  984  984  GLY GLY A . n 
A 1 967  SER 967  985  985  SER SER A . n 
A 1 968  THR 968  986  986  THR THR A . n 
A 1 969  TRP 969  987  987  TRP TRP A . n 
A 1 970  LEU 970  988  988  LEU LEU A . n 
A 1 971  SER 971  989  989  SER SER A . n 
A 1 972  ALA 972  990  990  ALA ALA A . n 
A 1 973  PHE 973  991  991  PHE PHE A . n 
A 1 974  VAL 974  992  992  VAL VAL A . n 
A 1 975  LEU 975  993  993  LEU LEU A . n 
A 1 976  ARG 976  994  994  ARG ARG A . n 
A 1 977  CYS 977  995  995  CYS CYS A . n 
A 1 978  PHE 978  996  996  PHE PHE A . n 
A 1 979  LEU 979  997  997  LEU LEU A . n 
A 1 980  GLU 980  998  998  GLU GLU A . n 
A 1 981  ALA 981  999  999  ALA ALA A . n 
A 1 982  ASP 982  1000 1000 ASP ASP A . n 
A 1 983  PRO 983  1001 1001 PRO PRO A . n 
A 1 984  TYR 984  1002 1002 TYR TYR A . n 
A 1 985  ILE 985  1003 1003 ILE ILE A . n 
A 1 986  ASP 986  1004 1004 ASP ASP A . n 
A 1 987  ILE 987  1005 1005 ILE ILE A . n 
A 1 988  ASP 988  1006 1006 ASP ASP A . n 
A 1 989  GLN 989  1007 1007 GLN GLN A . n 
A 1 990  ASN 990  1008 1008 ASN ASN A . n 
A 1 991  VAL 991  1009 1009 VAL VAL A . n 
A 1 992  LEU 992  1010 1010 LEU LEU A . n 
A 1 993  HIS 993  1011 1011 HIS HIS A . n 
A 1 994  ARG 994  1012 1012 ARG ARG A . n 
A 1 995  THR 995  1013 1013 THR THR A . n 
A 1 996  TYR 996  1014 1014 TYR TYR A . n 
A 1 997  THR 997  1015 1015 THR THR A . n 
A 1 998  TRP 998  1016 1016 TRP TRP A . n 
A 1 999  LEU 999  1017 1017 LEU LEU A . n 
A 1 1000 LYS 1000 1018 1018 LYS LYS A . n 
A 1 1001 GLY 1001 1019 1019 GLY GLY A . n 
A 1 1002 HIS 1002 1020 1020 HIS HIS A . n 
A 1 1003 GLN 1003 1021 1021 GLN GLN A . n 
A 1 1004 LYS 1004 1022 1022 LYS LYS A . n 
A 1 1005 SER 1005 1023 1023 SER SER A . n 
A 1 1006 ASN 1006 1024 1024 ASN ASN A . n 
A 1 1007 GLY 1007 1025 1025 GLY GLY A . n 
A 1 1008 GLU 1008 1026 1026 GLU GLU A . n 
A 1 1009 PHE 1009 1027 1027 PHE PHE A . n 
A 1 1010 TRP 1010 1028 1028 TRP TRP A . n 
A 1 1011 ASP 1011 1029 1029 ASP ASP A . n 
A 1 1012 PRO 1012 1030 1030 PRO PRO A . n 
A 1 1013 GLY 1013 1031 1031 GLY GLY A . n 
A 1 1014 ARG 1014 1032 1032 ARG ARG A . n 
A 1 1015 VAL 1015 1033 1033 VAL VAL A . n 
A 1 1016 ILE 1016 1034 1034 ILE ILE A . n 
A 1 1017 HIS 1017 1035 1035 HIS HIS A . n 
A 1 1018 SER 1018 1036 1036 SER SER A . n 
A 1 1019 GLU 1019 1037 1037 GLU GLU A . n 
A 1 1020 LEU 1020 1038 1038 LEU LEU A . n 
A 1 1021 GLN 1021 1039 1039 GLN GLN A . n 
A 1 1022 GLY 1022 1040 1040 GLY GLY A . n 
A 1 1023 GLY 1023 1041 1041 GLY GLY A . n 
A 1 1024 ASN 1024 1042 1042 ASN ASN A . n 
A 1 1025 LYS 1025 1043 1043 LYS LYS A . n 
A 1 1026 SER 1026 1044 1044 SER SER A . n 
A 1 1027 PRO 1027 1045 1045 PRO PRO A . n 
A 1 1028 VAL 1028 1046 1046 VAL VAL A . n 
A 1 1029 THR 1029 1047 1047 THR THR A . n 
A 1 1030 LEU 1030 1048 1048 LEU LEU A . n 
A 1 1031 THR 1031 1049 1049 THR THR A . n 
A 1 1032 ALA 1032 1050 1050 ALA ALA A . n 
A 1 1033 TYR 1033 1051 1051 TYR TYR A . n 
A 1 1034 ILE 1034 1052 1052 ILE ILE A . n 
A 1 1035 VAL 1035 1053 1053 VAL VAL A . n 
A 1 1036 THR 1036 1054 1054 THR THR A . n 
A 1 1037 SER 1037 1055 1055 SER SER A . n 
A 1 1038 LEU 1038 1056 1056 LEU LEU A . n 
A 1 1039 LEU 1039 1057 1057 LEU LEU A . n 
A 1 1040 GLY 1040 1058 1058 GLY GLY A . n 
A 1 1041 TYR 1041 1059 1059 TYR TYR A . n 
A 1 1042 ARG 1042 1060 1060 ARG ARG A . n 
A 1 1043 LYS 1043 1061 1061 LYS LYS A . n 
A 1 1044 TYR 1044 1062 1062 TYR TYR A . n 
A 1 1045 GLN 1045 1063 1063 GLN GLN A . n 
A 1 1046 PRO 1046 1064 1064 PRO PRO A . n 
A 1 1047 ASN 1047 1065 1065 ASN ASN A . n 
A 1 1048 ILE 1048 1066 1066 ILE ILE A . n 
A 1 1049 ASP 1049 1067 1067 ASP ASP A . n 
A 1 1050 VAL 1050 1068 1068 VAL VAL A . n 
A 1 1051 GLN 1051 1069 1069 GLN GLN A . n 
A 1 1052 GLU 1052 1070 1070 GLU GLU A . n 
A 1 1053 SER 1053 1071 1071 SER SER A . n 
A 1 1054 ILE 1054 1072 1072 ILE ILE A . n 
A 1 1055 HIS 1055 1073 1073 HIS HIS A . n 
A 1 1056 PHE 1056 1074 1074 PHE PHE A . n 
A 1 1057 LEU 1057 1075 1075 LEU LEU A . n 
A 1 1058 GLU 1058 1076 1076 GLU GLU A . n 
A 1 1059 SER 1059 1077 1077 SER SER A . n 
A 1 1060 GLU 1060 1078 1078 GLU GLU A . n 
A 1 1061 PHE 1061 1079 1079 PHE PHE A . n 
A 1 1062 SER 1062 1080 1080 SER SER A . n 
A 1 1063 ARG 1063 1081 1081 ARG ARG A . n 
A 1 1064 GLY 1064 1082 1082 GLY GLY A . n 
A 1 1065 ILE 1065 1083 1083 ILE ILE A . n 
A 1 1066 SER 1066 1084 1084 SER SER A . n 
A 1 1067 ASP 1067 1085 1085 ASP ASP A . n 
A 1 1068 ASN 1068 1086 1086 ASN ASN A . n 
A 1 1069 TYR 1069 1087 1087 TYR TYR A . n 
A 1 1070 THR 1070 1088 1088 THR THR A . n 
A 1 1071 LEU 1071 1089 1089 LEU LEU A . n 
A 1 1072 ALA 1072 1090 1090 ALA ALA A . n 
A 1 1073 LEU 1073 1091 1091 LEU LEU A . n 
A 1 1074 ILE 1074 1092 1092 ILE ILE A . n 
A 1 1075 THR 1075 1093 1093 THR THR A . n 
A 1 1076 TYR 1076 1094 1094 TYR TYR A . n 
A 1 1077 ALA 1077 1095 1095 ALA ALA A . n 
A 1 1078 LEU 1078 1096 1096 LEU LEU A . n 
A 1 1079 SER 1079 1097 1097 SER SER A . n 
A 1 1080 SER 1080 1098 1098 SER SER A . n 
A 1 1081 VAL 1081 1099 1099 VAL VAL A . n 
A 1 1082 GLY 1082 1100 1100 GLY GLY A . n 
A 1 1083 SER 1083 1101 1101 SER SER A . n 
A 1 1084 PRO 1084 1102 1102 PRO PRO A . n 
A 1 1085 LYS 1085 1103 1103 LYS LYS A . n 
A 1 1086 ALA 1086 1104 1104 ALA ALA A . n 
A 1 1087 LYS 1087 1105 1105 LYS LYS A . n 
A 1 1088 GLU 1088 1106 1106 GLU GLU A . n 
A 1 1089 ALA 1089 1107 1107 ALA ALA A . n 
A 1 1090 LEU 1090 1108 1108 LEU LEU A . n 
A 1 1091 ASN 1091 1109 1109 ASN ASN A . n 
A 1 1092 MET 1092 1110 1110 MET MET A . n 
A 1 1093 LEU 1093 1111 1111 LEU LEU A . n 
A 1 1094 THR 1094 1112 1112 THR THR A . n 
A 1 1095 TRP 1095 1113 1113 TRP TRP A . n 
A 1 1096 ARG 1096 1114 1114 ARG ARG A . n 
A 1 1097 ALA 1097 1115 1115 ALA ALA A . n 
A 1 1098 GLU 1098 1116 1116 GLU GLU A . n 
A 1 1099 GLN 1099 1117 1117 GLN GLN A . n 
A 1 1100 GLU 1100 1118 1118 GLU GLU A . n 
A 1 1101 GLY 1101 1119 1119 GLY GLY A . n 
A 1 1102 GLY 1102 1120 1120 GLY GLY A . n 
A 1 1103 MET 1103 1121 1121 MET MET A . n 
A 1 1104 GLN 1104 1122 1122 GLN GLN A . n 
A 1 1105 PHE 1105 1123 1123 PHE PHE A . n 
A 1 1106 TRP 1106 1124 1124 TRP TRP A . n 
A 1 1107 VAL 1107 1125 1125 VAL VAL A . n 
A 1 1108 SER 1108 1126 1126 SER SER A . n 
A 1 1109 SER 1109 1127 1127 SER SER A . n 
A 1 1110 GLU 1110 1128 1128 GLU GLU A . n 
A 1 1111 SER 1111 1129 ?    ?   ?   A . n 
A 1 1112 LYS 1112 1130 ?    ?   ?   A . n 
A 1 1113 LEU 1113 1131 ?    ?   ?   A . n 
A 1 1114 SER 1114 1132 ?    ?   ?   A . n 
A 1 1115 ASP 1115 1133 ?    ?   ?   A . n 
A 1 1116 SER 1116 1134 ?    ?   ?   A . n 
A 1 1117 TRP 1117 1135 ?    ?   ?   A . n 
A 1 1118 GLN 1118 1136 ?    ?   ?   A . n 
A 1 1119 PRO 1119 1137 ?    ?   ?   A . n 
A 1 1120 ARG 1120 1138 ?    ?   ?   A . n 
A 1 1121 SER 1121 1139 1139 SER SER A . n 
A 1 1122 LEU 1122 1140 1140 LEU LEU A . n 
A 1 1123 ASP 1123 1141 1141 ASP ASP A . n 
A 1 1124 ILE 1124 1142 1142 ILE ILE A . n 
A 1 1125 GLU 1125 1143 1143 GLU GLU A . n 
A 1 1126 VAL 1126 1144 1144 VAL VAL A . n 
A 1 1127 ALA 1127 1145 1145 ALA ALA A . n 
A 1 1128 ALA 1128 1146 1146 ALA ALA A . n 
A 1 1129 TYR 1129 1147 1147 TYR TYR A . n 
A 1 1130 ALA 1130 1148 1148 ALA ALA A . n 
A 1 1131 LEU 1131 1149 1149 LEU LEU A . n 
A 1 1132 LEU 1132 1150 1150 LEU LEU A . n 
A 1 1133 SER 1133 1151 1151 SER SER A . n 
A 1 1134 HIS 1134 1152 1152 HIS HIS A . n 
A 1 1135 PHE 1135 1153 1153 PHE PHE A . n 
A 1 1136 LEU 1136 1154 1154 LEU LEU A . n 
A 1 1137 GLN 1137 1155 1155 GLN GLN A . n 
A 1 1138 PHE 1138 1156 1156 PHE PHE A . n 
A 1 1139 GLN 1139 1157 1157 GLN GLN A . n 
A 1 1140 THR 1140 1158 1158 THR THR A . n 
A 1 1141 SER 1141 1159 1159 SER SER A . n 
A 1 1142 GLU 1142 1160 1160 GLU GLU A . n 
A 1 1143 GLY 1143 1161 1161 GLY GLY A . n 
A 1 1144 ILE 1144 1162 1162 ILE ILE A . n 
A 1 1145 PRO 1145 1163 1163 PRO PRO A . n 
A 1 1146 ILE 1146 1164 1164 ILE ILE A . n 
A 1 1147 MET 1147 1165 1165 MET MET A . n 
A 1 1148 ARG 1148 1166 1166 ARG ARG A . n 
A 1 1149 TRP 1149 1167 1167 TRP TRP A . n 
A 1 1150 LEU 1150 1168 1168 LEU LEU A . n 
A 1 1151 SER 1151 1169 1169 SER SER A . n 
A 1 1152 ARG 1152 1170 1170 ARG ARG A . n 
A 1 1153 GLN 1153 1171 1171 GLN GLN A . n 
A 1 1154 ARG 1154 1172 1172 ARG ARG A . n 
A 1 1155 ASN 1155 1173 1173 ASN ASN A . n 
A 1 1156 SER 1156 1174 1174 SER SER A . n 
A 1 1157 LEU 1157 1175 1175 LEU LEU A . n 
A 1 1158 GLY 1158 1176 1176 GLY GLY A . n 
A 1 1159 GLY 1159 1177 1177 GLY GLY A . n 
A 1 1160 PHE 1160 1178 1178 PHE PHE A . n 
A 1 1161 ALA 1161 1179 1179 ALA ALA A . n 
A 1 1162 SER 1162 1180 1180 SER SER A . n 
A 1 1163 THR 1163 1181 1181 THR THR A . n 
A 1 1164 GLN 1164 1182 1182 GLN GLN A . n 
A 1 1165 ASP 1165 1183 1183 ASP ASP A . n 
A 1 1166 THR 1166 1184 1184 THR THR A . n 
A 1 1167 THR 1167 1185 1185 THR THR A . n 
A 1 1168 VAL 1168 1186 1186 VAL VAL A . n 
A 1 1169 ALA 1169 1187 1187 ALA ALA A . n 
A 1 1170 LEU 1170 1188 1188 LEU LEU A . n 
A 1 1171 LYS 1171 1189 1189 LYS LYS A . n 
A 1 1172 ALA 1172 1190 1190 ALA ALA A . n 
A 1 1173 LEU 1173 1191 1191 LEU LEU A . n 
A 1 1174 SER 1174 1192 1192 SER SER A . n 
A 1 1175 GLU 1175 1193 1193 GLU GLU A . n 
A 1 1176 PHE 1176 1194 1194 PHE PHE A . n 
A 1 1177 ALA 1177 1195 1195 ALA ALA A . n 
A 1 1178 ALA 1178 1196 1196 ALA ALA A . n 
A 1 1179 LEU 1179 1197 1197 LEU LEU A . n 
A 1 1180 MET 1180 1198 1198 MET MET A . n 
A 1 1181 ASN 1181 1199 1199 ASN ASN A . n 
A 1 1182 THR 1182 1200 1200 THR THR A . n 
A 1 1183 GLU 1183 1201 1201 GLU GLU A . n 
A 1 1184 ARG 1184 1202 1202 ARG ARG A . n 
A 1 1185 THR 1185 1203 1203 THR THR A . n 
A 1 1186 ASN 1186 1204 1204 ASN ASN A . n 
A 1 1187 ILE 1187 1205 1205 ILE ILE A . n 
A 1 1188 GLN 1188 1206 1206 GLN GLN A . n 
A 1 1189 VAL 1189 1207 1207 VAL VAL A . n 
A 1 1190 THR 1190 1208 1208 THR THR A . n 
A 1 1191 VAL 1191 1209 1209 VAL VAL A . n 
A 1 1192 THR 1192 1210 1210 THR THR A . n 
A 1 1193 GLY 1193 1211 1211 GLY GLY A . n 
A 1 1194 PRO 1194 1212 1212 PRO PRO A . n 
A 1 1195 SER 1195 1213 1213 SER SER A . n 
A 1 1196 SER 1196 1214 1214 SER SER A . n 
A 1 1197 PRO 1197 1215 1215 PRO PRO A . n 
A 1 1198 SER 1198 1216 1216 SER SER A . n 
A 1 1199 PRO 1199 1217 1217 PRO PRO A . n 
A 1 1200 VAL 1200 1218 1218 VAL VAL A . n 
A 1 1201 LYS 1201 1219 1219 LYS LYS A . n 
A 1 1202 PHE 1202 1220 1220 PHE PHE A . n 
A 1 1203 LEU 1203 1221 1221 LEU LEU A . n 
A 1 1204 ILE 1204 1222 1222 ILE ILE A . n 
A 1 1205 ASP 1205 1223 1223 ASP ASP A . n 
A 1 1206 THR 1206 1224 1224 THR THR A . n 
A 1 1207 HIS 1207 1225 1225 HIS HIS A . n 
A 1 1208 ASN 1208 1226 1226 ASN ASN A . n 
A 1 1209 ARG 1209 1227 1227 ARG ARG A . n 
A 1 1210 LEU 1210 1228 1228 LEU LEU A . n 
A 1 1211 LEU 1211 1229 1229 LEU LEU A . n 
A 1 1212 LEU 1212 1230 1230 LEU LEU A . n 
A 1 1213 GLN 1213 1231 1231 GLN GLN A . n 
A 1 1214 THR 1214 1232 1232 THR THR A . n 
A 1 1215 ALA 1215 1233 1233 ALA ALA A . n 
A 1 1216 GLU 1216 1234 1234 GLU GLU A . n 
A 1 1217 LEU 1217 1235 1235 LEU LEU A . n 
A 1 1218 ALA 1218 1236 1236 ALA ALA A . n 
A 1 1219 VAL 1219 1237 1237 VAL VAL A . n 
A 1 1220 VAL 1220 1238 1238 VAL VAL A . n 
A 1 1221 GLN 1221 1239 1239 GLN GLN A . n 
A 1 1222 PRO 1222 1240 1240 PRO PRO A . n 
A 1 1223 THR 1223 1241 1241 THR THR A . n 
A 1 1224 ALA 1224 1242 1242 ALA ALA A . n 
A 1 1225 VAL 1225 1243 1243 VAL VAL A . n 
A 1 1226 ASN 1226 1244 1244 ASN ASN A . n 
A 1 1227 ILE 1227 1245 1245 ILE ILE A . n 
A 1 1228 SER 1228 1246 1246 SER SER A . n 
A 1 1229 ALA 1229 1247 1247 ALA ALA A . n 
A 1 1230 ASN 1230 1248 1248 ASN ASN A . n 
A 1 1231 GLY 1231 1249 1249 GLY GLY A . n 
A 1 1232 PHE 1232 1250 1250 PHE PHE A . n 
A 1 1233 GLY 1233 1251 1251 GLY GLY A . n 
A 1 1234 PHE 1234 1252 1252 PHE PHE A . n 
A 1 1235 ALA 1235 1253 1253 ALA ALA A . n 
A 1 1236 ILE 1236 1254 1254 ILE ILE A . n 
A 1 1237 CYS 1237 1255 1255 CYS CYS A . n 
A 1 1238 GLN 1238 1256 1256 GLN GLN A . n 
A 1 1239 LEU 1239 1257 1257 LEU LEU A . n 
A 1 1240 ASN 1240 1258 1258 ASN ASN A . n 
A 1 1241 VAL 1241 1259 1259 VAL VAL A . n 
A 1 1242 VAL 1242 1260 1260 VAL VAL A . n 
A 1 1243 TYR 1243 1261 1261 TYR TYR A . n 
A 1 1244 ASN 1244 1262 1262 ASN ASN A . n 
A 1 1245 VAL 1245 1263 1263 VAL VAL A . n 
A 1 1246 LYS 1246 1264 1264 LYS LYS A . n 
A 1 1247 ALA 1247 1265 ?    ?   ?   A . n 
A 1 1248 SER 1248 1266 ?    ?   ?   A . n 
A 1 1249 GLY 1249 1267 ?    ?   ?   A . n 
A 1 1250 SER 1250 1268 ?    ?   ?   A . n 
A 1 1251 SER 1251 1269 ?    ?   ?   A . n 
A 1 1252 ARG 1252 1270 ?    ?   ?   A . n 
A 1 1253 ARG 1253 1271 ?    ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAG 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAG 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 NAG 1 1301 2041 NAG NAG A . 
C 2 NAG 1 1302 2118 NAG NAG A . 
D 2 NAG 1 1303 3244 NAG NAG A . 
E 2 NAG 1 1304 2365 NAG NAG A . 
F 2 NAG 1 1305 2419 NAG NAG A . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FX2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FX2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FX2 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9FX2 
_struct.title                        'Structure of methylamine activated CD109' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FX2 
_struct_keywords.text            
'Protease inhibitor, thioester activation, intermediate conformation, alpha-macroglobulin, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CD109_HUMAN 
_struct_ref.pdbx_db_accession          Q6YHK3 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;VAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEI
YELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLS
QQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVK
GDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTN
VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYT
VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVV
SRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVT
QPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYA
ERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE
LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFP
IRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIG
DVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYD
PSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRK
YQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLD
IEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFL
IDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRR
;
_struct_ref.pdbx_align_begin           22 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9FX2 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1253 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q6YHK3 
_struct_ref_seq.db_align_beg                  22 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1271 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       22 
_struct_ref_seq.pdbx_auth_seq_align_end       1271 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FX2 SER A 1   ? UNP Q6YHK3 ?   ?   'expression tag' 19  1 
1 9FX2 GLY A 2   ? UNP Q6YHK3 ?   ?   'expression tag' 20  2 
1 9FX2 SER A 3   ? UNP Q6YHK3 ?   ?   'expression tag' 21  3 
1 9FX2 GLU A 646 ? UNP Q6YHK3 PHE 664 conflict         664 4 
1 9FX2 ASN A 647 ? UNP Q6YHK3 MET 665 conflict         665 5 
1 9FX2 LEU A 648 ? UNP Q6YHK3 GLU 666 conflict         666 6 
1 9FX2 TYR A 649 ? UNP Q6YHK3 GLU 667 conflict         667 7 
1 9FX2 PHE A 650 ? UNP Q6YHK3 ASN 668 conflict         668 8 
1 9FX2 GLN A 651 ? UNP Q6YHK3 GLU 669 conflict         669 9 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 283  ? SER A 288  ? ASN A 301  SER A 306  1 ? 6  
HELX_P HELX_P2  AA2 THR A 363  ? ASN A 369  ? THR A 381  ASN A 387  1 ? 7  
HELX_P HELX_P3  AA3 GLU A 504  ? THR A 508  ? GLU A 522  THR A 526  5 ? 5  
HELX_P HELX_P4  AA4 LYS A 576  ? ASN A 582  ? LYS A 594  ASN A 600  1 ? 7  
HELX_P HELX_P5  AA5 THR A 588  ? ASN A 600  ? THR A 606  ASN A 618  1 ? 13 
HELX_P HELX_P6  AA6 MET A 609  ? GLU A 617  ? MET A 627  GLU A 635  1 ? 9  
HELX_P HELX_P7  AA7 SER A 889  ? LEU A 896  ? SER A 907  LEU A 914  1 ? 8  
HELX_P HELX_P8  AA8 CYS A 903  ? LYS A 925  ? CYS A 921  LYS A 943  1 ? 23 
HELX_P HELX_P9  AA9 THR A 928  ? TYR A 949  ? THR A 946  TYR A 967  1 ? 22 
HELX_P HELX_P10 AB1 PHE A 959  ? ASP A 963  ? PHE A 977  ASP A 981  5 ? 5  
HELX_P HELX_P11 AB2 SER A 967  ? ASP A 982  ? SER A 985  ASP A 1000 1 ? 16 
HELX_P HELX_P12 AB3 ASP A 988  ? HIS A 1002 ? ASP A 1006 HIS A 1020 1 ? 15 
HELX_P HELX_P13 AB4 HIS A 1017 ? GLY A 1022 ? HIS A 1035 GLY A 1040 1 ? 6  
HELX_P HELX_P14 AB5 SER A 1026 ? LEU A 1039 ? SER A 1044 LEU A 1057 1 ? 14 
HELX_P HELX_P15 AB6 GLY A 1040 ? TYR A 1044 ? GLY A 1058 TYR A 1062 5 ? 5  
HELX_P HELX_P16 AB7 VAL A 1050 ? GLY A 1064 ? VAL A 1068 GLY A 1082 1 ? 15 
HELX_P HELX_P17 AB8 ASP A 1067 ? VAL A 1081 ? ASP A 1085 VAL A 1099 1 ? 15 
HELX_P HELX_P18 AB9 PRO A 1084 ? ARG A 1096 ? PRO A 1102 ARG A 1114 1 ? 13 
HELX_P HELX_P19 AC1 LEU A 1122 ? GLN A 1137 ? LEU A 1140 GLN A 1155 1 ? 16 
HELX_P HELX_P20 AC2 THR A 1140 ? GLU A 1142 ? THR A 1158 GLU A 1160 5 ? 3  
HELX_P HELX_P21 AC3 GLY A 1143 ? GLN A 1153 ? GLY A 1161 GLN A 1171 1 ? 11 
HELX_P HELX_P22 AC4 THR A 1163 ? MET A 1180 ? THR A 1181 MET A 1198 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 512  SG  ? ? ? 1_555 A CYS 618 SG ? ? A CYS 530  A CYS 636  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
covale1 covale one ? A ASN 23   ND2 ? ? ? 1_555 B NAG .   C1 ? ? A ASN 41   A NAG 1301 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale2 covale one ? A ASN 100  ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 118  A NAG 1302 1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale3 covale one ? A ASN 347  ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 365  A NAG 1304 1_555 ? ? ? ? ? ? ? 1.430 ? N-Glycosylation 
covale4 covale one ? A ASN 401  ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 419  A NAG 1305 1_555 ? ? ? ? ? ? ? 1.474 ? N-Glycosylation 
covale5 covale one ? A ASN 1226 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 1244 A NAG 1303 1_555 ? ? ? ? ? ? ? 1.436 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG B .   ? ASN A 23   ? NAG A 1301 ? 1_555 ASN A 41   ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG C .   ? ASN A 100  ? NAG A 1302 ? 1_555 ASN A 118  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG D .   ? ASN A 1226 ? NAG A 1303 ? 1_555 ASN A 1244 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG E .   ? ASN A 347  ? NAG A 1304 ? 1_555 ASN A 365  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 NAG F .   ? ASN A 401  ? NAG A 1305 ? 1_555 ASN A 419  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6 CYS A 512 ? CYS A 618  ? CYS A 530  ? 1_555 CYS A 636  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 THR 508  A . ? THR 526  A PRO 509  A ? PRO 527  A 1 -2.36 
2 GLN 1221 A . ? GLN 1239 A PRO 1222 A ? PRO 1240 A 1 -0.73 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 5 ? 
AA7 ? 3 ? 
AA8 ? 4 ? 
AA9 ? 3 ? 
AB1 ? 4 ? 
AB2 ? 3 ? 
AB3 ? 5 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
AB6 ? 5 ? 
AB7 ? 4 ? 
AB8 ? 4 ? 
AB9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 67   ? THR A 71   ? PHE A 85   THR A 89   
AA1 2 THR A 25   ? LEU A 30   ? THR A 43   LEU A 48   
AA1 3 PHE A 10   ? PRO A 15   ? PHE A 28   PRO A 33   
AA1 4 LEU A 620  ? THR A 624  ? LEU A 638  THR A 642  
AA2 1 ILE A 17   ? ILE A 18   ? ILE A 35   ILE A 36   
AA2 2 ILE A 96   ? PHE A 106  ? ILE A 114  PHE A 124  
AA2 3 TYR A 84   ? ARG A 91   ? TYR A 102  ARG A 109  
AA2 4 GLN A 37   ? LEU A 45   ? GLN A 55   LEU A 63   
AA2 5 SER A 54   ? GLU A 63   ? SER A 72   GLU A 81   
AA3 1 SER A 112  ? THR A 117  ? SER A 130  THR A 135  
AA3 2 GLU A 127  ? LEU A 135  ? GLU A 145  LEU A 153  
AA3 3 VAL A 170  ? GLN A 176  ? VAL A 188  GLN A 194  
AA4 1 LEU A 121  ? TYR A 122  ? LEU A 139  TYR A 140  
AA4 2 GLN A 195  ? VAL A 203  ? GLN A 213  VAL A 221  
AA4 3 GLY A 184  ? VAL A 192  ? GLY A 202  VAL A 210  
AA4 4 SER A 145  ? LYS A 151  ? SER A 163  LYS A 169  
AA4 5 LEU A 157  ? GLN A 165  ? LEU A 175  GLN A 183  
AA5 1 PHE A 211  ? GLN A 216  ? PHE A 229  GLN A 234  
AA5 2 LEU A 228  ? TYR A 236  ? LEU A 246  TYR A 254  
AA5 3 SER A 271  ? PHE A 276  ? SER A 289  PHE A 294  
AA6 1 TYR A 220  ? SER A 222  ? TYR A 238  SER A 240  
AA6 2 SER A 317  ? LYS A 327  ? SER A 335  LYS A 345  
AA6 3 VAL A 303  ? GLU A 311  ? VAL A 321  GLU A 329  
AA6 4 LYS A 243  ? PRO A 252  ? LYS A 261  PRO A 270  
AA6 5 ILE A 262  ? ASN A 269  ? ILE A 280  ASN A 287  
AA7 1 TYR A 331  ? PHE A 336  ? TYR A 349  PHE A 354  
AA7 2 PHE A 348  ? ARG A 356  ? PHE A 366  ARG A 374  
AA7 3 THR A 409  ? PHE A 414  ? THR A 427  PHE A 432  
AA8 1 GLU A 395  ? TYR A 402  ? GLU A 413  TYR A 420  
AA8 2 VAL A 371  ? ARG A 378  ? VAL A 389  ARG A 396  
AA8 3 GLU A 422  ? PHE A 429  ? GLU A 440  PHE A 447  
AA8 4 SER A 432  ? VAL A 438  ? SER A 450  VAL A 456  
AA9 1 ILE A 450  ? LYS A 453  ? ILE A 468  LYS A 471  
AA9 2 PHE A 465  ? GLY A 471  ? PHE A 483  GLY A 489  
AA9 3 MET A 498  ? LEU A 501  ? MET A 516  LEU A 519  
AB1 1 GLN A 487  ? GLN A 494  ? GLN A 505  GLN A 512  
AB1 2 LEU A 478  ? SER A 484  ? LEU A 496  SER A 502  
AB1 3 LYS A 510  ? ILE A 518  ? LYS A 528  ILE A 536  
AB1 4 ILE A 524  ? PRO A 532  ? ILE A 542  PRO A 550  
AB2 1 ILE A 541  ? TRP A 545  ? ILE A 559  TRP A 563  
AB2 2 LYS A 555  ? VAL A 562  ? LYS A 573  VAL A 580  
AB2 3 TYR A 688  ? THR A 694  ? TYR A 706  THR A 712  
AB3 1 LYS A 549  ? ALA A 550  ? LYS A 567  ALA A 568  
AB3 2 VAL A 722  ? ALA A 726  ? VAL A 740  ALA A 744  
AB3 3 THR A 700  ? SER A 710  ? THR A 718  SER A 728  
AB3 4 ILE A 568  ? VAL A 574  ? ILE A 586  VAL A 592  
AB3 5 THR A 675  ? ASN A 682  ? THR A 693  ASN A 700  
AB4 1 LYS A 549  ? ALA A 550  ? LYS A 567  ALA A 568  
AB4 2 VAL A 722  ? ALA A 726  ? VAL A 740  ALA A 744  
AB4 3 THR A 700  ? SER A 710  ? THR A 718  SER A 728  
AB4 4 GLY A 714  ? LEU A 717  ? GLY A 732  LEU A 735  
AB5 1 PHE A 730  ? LEU A 734  ? PHE A 748  LEU A 752  
AB5 2 PHE A 746  ? ASN A 754  ? PHE A 764  ASN A 772  
AB5 3 ASP A 796  ? PRO A 806  ? ASP A 814  PRO A 824  
AB5 4 PHE A 772  ? ILE A 774  ? PHE A 790  ILE A 792  
AB6 1 SER A 739  ? ILE A 741  ? SER A 757  ILE A 759  
AB6 2 SER A 824  ? LYS A 834  ? SER A 842  LYS A 852  
AB6 3 GLY A 810  ? LEU A 819  ? GLY A 828  LEU A 837  
AB6 4 THR A 760  ? ILE A 766  ? THR A 778  ILE A 784  
AB6 5 GLN A 787  ? VAL A 792  ? GLN A 805  VAL A 810  
AB7 1 ILE A 838  ? LEU A 850  ? ILE A 856  LEU A 868  
AB7 2 GLY A 1233 ? VAL A 1245 ? GLY A 1251 VAL A 1263 
AB7 3 ARG A 876  ? ILE A 882  ? ARG A 894  ILE A 900  
AB7 4 GLN A 1213 ? LEU A 1217 ? GLN A 1231 LEU A 1235 
AB8 1 SER A 857  ? PHE A 864  ? SER A 875  PHE A 882  
AB8 2 THR A 1223 ? ASN A 1230 ? THR A 1241 ASN A 1248 
AB8 3 ASN A 1186 ? GLY A 1193 ? ASN A 1204 GLY A 1211 
AB8 4 SER A 1196 ? ASP A 1205 ? SER A 1214 ASP A 1223 
AB9 1 GLU A 1098 ? GLN A 1099 ? GLU A 1116 GLN A 1117 
AB9 2 GLN A 1104 ? PHE A 1105 ? GLN A 1122 PHE A 1123 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LYS A 68   ? O LYS A 86   N VAL A 28   ? N VAL A 46   
AA1 2 3 O GLY A 27   ? O GLY A 45   N THR A 13   ? N THR A 31   
AA1 3 4 N ALA A 14   ? N ALA A 32   O TRP A 621  ? O TRP A 639  
AA2 1 2 N ILE A 18   ? N ILE A 36   O SER A 105  ? O SER A 123  
AA2 2 3 O ASN A 100  ? O ASN A 118  N VAL A 88   ? N VAL A 106  
AA2 3 4 O ARG A 87   ? O ARG A 105  N GLU A 43   ? N GLU A 61   
AA2 4 5 N VAL A 40   ? N VAL A 58   O GLY A 60   ? O GLY A 78   
AA3 1 2 N GLN A 116  ? N GLN A 134  O ARG A 131  ? O ARG A 149  
AA3 2 3 N VAL A 128  ? N VAL A 146  O PHE A 175  ? O PHE A 193  
AA4 1 2 N TYR A 122  ? N TYR A 140  O GLN A 202  ? O GLN A 220  
AA4 2 3 O GLN A 195  ? O GLN A 213  N VAL A 192  ? N VAL A 210  
AA4 3 4 O GLN A 189  ? O GLN A 207  N LEU A 149  ? N LEU A 167  
AA4 4 5 N ILE A 148  ? N ILE A 166  O TRP A 161  ? O TRP A 179  
AA5 1 2 N GLU A 212  ? N GLU A 230  O LYS A 235  ? O LYS A 253  
AA5 2 3 N GLY A 230  ? N GLY A 248  O PHE A 274  ? O PHE A 292  
AA6 1 2 N CYS A 221  ? N CYS A 239  O LYS A 327  ? O LYS A 345  
AA6 2 3 O VAL A 320  ? O VAL A 338  N THR A 307  ? N THR A 325  
AA6 3 4 O THR A 310  ? O THR A 328  N ASP A 245  ? N ASP A 263  
AA6 4 5 N LEU A 248  ? N LEU A 266  O LYS A 264  ? O LYS A 282  
AA7 1 2 N ILE A 332  ? N ILE A 350  O THR A 355  ? O THR A 373  
AA7 2 3 N VAL A 352  ? N VAL A 370  O PHE A 410  ? O PHE A 428  
AA8 1 2 O TYR A 402  ? O TYR A 420  N VAL A 371  ? N VAL A 389  
AA8 2 3 N ARG A 378  ? N ARG A 396  O GLU A 422  ? O GLU A 440  
AA8 3 4 N ALA A 427  ? N ALA A 445  O SER A 434  ? O SER A 452  
AA9 1 2 N LYS A 453  ? N LYS A 471  O VAL A 468  ? O VAL A 486  
AA9 2 3 N PHE A 465  ? N PHE A 483  O LEU A 501  ? O LEU A 519  
AB1 1 2 O GLN A 487  ? O GLN A 505  N SER A 484  ? N SER A 502  
AB1 2 3 N MET A 481  ? N MET A 499  O ILE A 514  ? O ILE A 532  
AB1 3 4 N TYR A 517  ? N TYR A 535  O ILE A 525  ? O ILE A 543  
AB2 1 2 N TYR A 544  ? N TYR A 562  O ARG A 559  ? O ARG A 577  
AB2 2 3 N VAL A 556  ? N VAL A 574  O VAL A 693  ? O VAL A 711  
AB3 1 2 N ALA A 550  ? N ALA A 568  O GLN A 725  ? O GLN A 743  
AB3 2 3 O VAL A 722  ? O VAL A 740  N ALA A 704  ? N ALA A 722  
AB3 3 4 O VAL A 703  ? O VAL A 721  N VAL A 574  ? N VAL A 592  
AB3 4 5 N VAL A 569  ? N VAL A 587  O THR A 681  ? O THR A 699  
AB4 1 2 N ALA A 550  ? N ALA A 568  O GLN A 725  ? O GLN A 743  
AB4 2 3 O VAL A 722  ? O VAL A 740  N ALA A 704  ? N ALA A 722  
AB4 3 4 N VAL A 708  ? N VAL A 726  O GLY A 716  ? O GLY A 734  
AB5 1 2 N PHE A 733  ? N PHE A 751  O THR A 751  ? O THR A 769  
AB5 2 3 N ASN A 754  ? N ASN A 772  O ASP A 796  ? O ASP A 814  
AB5 3 4 O ARG A 805  ? O ARG A 823  N ASP A 773  ? N ASP A 791  
AB6 1 2 N VAL A 740  ? N VAL A 758  O LYS A 834  ? O LYS A 852  
AB6 2 3 O VAL A 833  ? O VAL A 851  N GLY A 810  ? N GLY A 828  
AB6 3 4 O THR A 817  ? O THR A 835  N ILE A 765  ? N ILE A 783  
AB6 4 5 N THR A 760  ? N THR A 778  O VAL A 792  ? O VAL A 810  
AB7 1 2 N GLN A 844  ? N GLN A 862  O LEU A 1239 ? O LEU A 1257 
AB7 2 3 O GLN A 1238 ? O GLN A 1256 N THR A 880  ? N THR A 898  
AB7 3 4 N VAL A 877  ? N VAL A 895  O LEU A 1217 ? O LEU A 1235 
AB8 1 2 N LYS A 860  ? N LYS A 878  O ILE A 1227 ? O ILE A 1245 
AB8 2 3 O SER A 1228 ? O SER A 1246 N THR A 1190 ? N THR A 1208 
AB8 3 4 N ILE A 1187 ? N ILE A 1205 O ILE A 1204 ? O ILE A 1222 
AB9 1 2 N GLU A 1098 ? N GLU A 1116 O PHE A 1105 ? O PHE A 1123 
# 
_pdbx_entry_details.entry_id                   9FX2 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            C 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            THR 
_pdbx_validate_rmsd_bond.auth_seq_id_1             421 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            N 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            VAL 
_pdbx_validate_rmsd_bond.auth_seq_id_2             422 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.480 
_pdbx_validate_rmsd_bond.bond_target_value         1.336 
_pdbx_validate_rmsd_bond.bond_deviation            0.144 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.023 
_pdbx_validate_rmsd_bond.linker_flag               Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 50   ? ? -133.63 -40.25  
2  1 PRO A 53   ? ? -69.64  -178.83 
3  1 VAL A 73   ? ? -93.53  -61.50  
4  1 ASN A 211  ? ? 58.64   -90.32  
5  1 VAL A 225  ? ? 49.45   70.74   
6  1 ASN A 365  ? ? -37.53  116.37  
7  1 THR A 515  ? ? -96.73  31.22   
8  1 PHE A 626  ? ? 79.88   -8.23   
9  1 ALA A 644  ? ? -94.54  56.54   
10 1 ASN A 645  ? ? -141.18 13.41   
11 1 THR A 718  ? ? -167.72 -167.98 
12 1 ASN A 753  ? ? -94.51  57.67   
13 1 LEU A 868  ? ? -99.28  30.32   
14 1 LYS A 943  ? ? 61.22   60.64   
15 1 ASN A 1042 ? ? 59.83   70.37   
16 1 LYS A 1043 ? ? -68.72  1.14    
17 1 GLN A 1157 ? ? -96.25  59.26   
18 1 LEU A 1175 ? ? -140.31 17.81   
19 1 SER A 1180 ? ? 60.40   -160.99 
20 1 ASN A 1204 ? ? -140.49 41.05   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FX2 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      A 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                Q6YHK3 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9FX2 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               230644 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 RIBOSOME 
_em_entity_assembly.name                 'Monomeric methylamine non-GPI bounded CD109' 
_em_entity_assembly.details              'C-terminal GPI-motif (residues 1421-1445) was removed' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9FX2 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1700 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Au-flat 1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9FX2 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FX2 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER 19   ? A SER 1    
2  1 Y 1 A GLY 20   ? A GLY 2    
3  1 Y 1 A SER 21   ? A SER 3    
4  1 Y 1 A VAL 22   ? A VAL 4    
5  1 Y 1 A ASN 307  ? A ASN 289  
6  1 Y 1 A GLY 308  ? A GLY 290  
7  1 Y 1 A LEU 309  ? A LEU 291  
8  1 Y 1 A SER 310  ? A SER 292  
9  1 Y 1 A GLU 311  ? A GLU 293  
10 1 Y 1 A TYR 312  ? A TYR 294  
11 1 Y 1 A LEU 313  ? A LEU 295  
12 1 Y 1 A ASP 314  ? A ASP 296  
13 1 Y 1 A LEU 315  ? A LEU 297  
14 1 Y 1 A THR 399  ? A THR 381  
15 1 Y 1 A GLU 400  ? A GLU 382  
16 1 Y 1 A TYR 401  ? A TYR 383  
17 1 Y 1 A TRP 402  ? A TRP 384  
18 1 Y 1 A SER 403  ? A SER 385  
19 1 Y 1 A GLY 404  ? A GLY 386  
20 1 Y 1 A SER 405  ? A SER 387  
21 1 Y 1 A ASN 406  ? A ASN 388  
22 1 Y 1 A SER 407  ? A SER 389  
23 1 Y 1 A GLY 408  ? A GLY 390  
24 1 Y 1 A ASN 409  ? A ASN 391  
25 1 Y 1 A GLN 410  ? A GLN 392  
26 1 Y 1 A LYS 648  ? A LYS 630  
27 1 Y 1 A ASP 649  ? A ASP 631  
28 1 Y 1 A TYR 650  ? A TYR 632  
29 1 Y 1 A ILE 651  ? A ILE 633  
30 1 Y 1 A ASP 652  ? A ASP 634  
31 1 Y 1 A GLY 653  ? A GLY 635  
32 1 Y 1 A VAL 654  ? A VAL 636  
33 1 Y 1 A TYR 655  ? A TYR 637  
34 1 Y 1 A ASP 656  ? A ASP 638  
35 1 Y 1 A ASN 657  ? A ASN 639  
36 1 Y 1 A ALA 658  ? A ALA 640  
37 1 Y 1 A GLU 659  ? A GLU 641  
38 1 Y 1 A TYR 660  ? A TYR 642  
39 1 Y 1 A ALA 661  ? A ALA 643  
40 1 Y 1 A GLU 662  ? A GLU 644  
41 1 Y 1 A ARG 663  ? A ARG 645  
42 1 Y 1 A GLU 664  ? A GLU 646  
43 1 Y 1 A ASN 665  ? A ASN 647  
44 1 Y 1 A LEU 666  ? A LEU 648  
45 1 Y 1 A TYR 667  ? A TYR 649  
46 1 Y 1 A PHE 668  ? A PHE 650  
47 1 Y 1 A GLN 669  ? A GLN 651  
48 1 Y 1 A GLY 670  ? A GLY 652  
49 1 Y 1 A HIS 671  ? A HIS 653  
50 1 Y 1 A ILE 672  ? A ILE 654  
51 1 Y 1 A VAL 673  ? A VAL 655  
52 1 Y 1 A ASP 674  ? A ASP 656  
53 1 Y 1 A ILE 675  ? A ILE 657  
54 1 Y 1 A HIS 676  ? A HIS 658  
55 1 Y 1 A ASP 677  ? A ASP 659  
56 1 Y 1 A PHE 678  ? A PHE 660  
57 1 Y 1 A SER 679  ? A SER 661  
58 1 Y 1 A LEU 680  ? A LEU 662  
59 1 Y 1 A GLY 681  ? A GLY 663  
60 1 Y 1 A SER 682  ? A SER 664  
61 1 Y 1 A SER 683  ? A SER 665  
62 1 Y 1 A PRO 684  ? A PRO 666  
63 1 Y 1 A HIS 685  ? A HIS 667  
64 1 Y 1 A VAL 686  ? A VAL 668  
65 1 Y 1 A ARG 687  ? A ARG 669  
66 1 Y 1 A LYS 688  ? A LYS 670  
67 1 Y 1 A SER 1129 ? A SER 1111 
68 1 Y 1 A LYS 1130 ? A LYS 1112 
69 1 Y 1 A LEU 1131 ? A LEU 1113 
70 1 Y 1 A SER 1132 ? A SER 1114 
71 1 Y 1 A ASP 1133 ? A ASP 1115 
72 1 Y 1 A SER 1134 ? A SER 1116 
73 1 Y 1 A TRP 1135 ? A TRP 1117 
74 1 Y 1 A GLN 1136 ? A GLN 1118 
75 1 Y 1 A PRO 1137 ? A PRO 1119 
76 1 Y 1 A ARG 1138 ? A ARG 1120 
77 1 Y 1 A ALA 1265 ? A ALA 1247 
78 1 Y 1 A SER 1266 ? A SER 1248 
79 1 Y 1 A GLY 1267 ? A GLY 1249 
80 1 Y 1 A SER 1268 ? A SER 1250 
81 1 Y 1 A SER 1269 ? A SER 1251 
82 1 Y 1 A ARG 1270 ? A ARG 1252 
83 1 Y 1 A ARG 1271 ? A ARG 1253 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-01 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FX2 
_em_admin.last_update        2025-03-19 
_em_admin.map_release_date   2025-03-19 
_em_admin.title              'Structure of methylamine activated CD109' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20  mM C8H18N2O4S  1 HEPES             
1 150 mM NaCl        2 'Sodium Chloride' 
1 4   mM C32H58N2O7S 3 CHAPS             
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    YES 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.165 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              'pcDNA3.1(+)' 
_em_entity_assembly_recombinant.strain               HEK293 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     11076 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   2305684 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC 4.04 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?    
MASKING                    ? 3  ? ? ? ?         ?    
'CTF CORRECTION'           ? 4  1 ? ? ?         ?    
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?    
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?    
'MODEL FITTING'            ? 7  ? 1 ? Coot      10   
OTHER                      ? 8  ? ? ? ?         ?    
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC 4.04 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? ?         ?    
CLASSIFICATION             ? 11 1 ? ? cryoSPARC 4.04 
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC 4.04 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX    1.20 
# 
_em_specimen.concentration           5.0 
_em_specimen.details                 'Monodisperse sample' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Danish Council for Independent Research' 
_pdbx_audit_support.country                Denmark 
_pdbx_audit_support.grant_number           DFF-2032-00111B 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   Q6YHK3 
# 
_atom_sites.entry_id                    9FX2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA A 1 5    ? 181.499 216.463 141.141 1.00 238.28 ? 23   ALA A N   1 
ATOM   2    C CA  . ALA A 1 5    ? 180.275 216.605 140.362 1.00 241.40 ? 23   ALA A CA  1 
ATOM   3    C C   . ALA A 1 5    ? 179.162 215.751 140.978 1.00 244.34 ? 23   ALA A C   1 
ATOM   4    O O   . ALA A 1 5    ? 179.452 214.785 141.684 1.00 244.18 ? 23   ALA A O   1 
ATOM   5    C CB  . ALA A 1 5    ? 180.523 216.206 138.914 1.00 238.86 ? 23   ALA A CB  1 
ATOM   6    N N   . PRO A 1 6    ? 177.896 216.091 140.724 1.00 244.25 ? 24   PRO A N   1 
ATOM   7    C CA  . PRO A 1 6    ? 176.808 215.301 141.308 1.00 241.01 ? 24   PRO A CA  1 
ATOM   8    C C   . PRO A 1 6    ? 176.590 214.003 140.549 1.00 237.21 ? 24   PRO A C   1 
ATOM   9    O O   . PRO A 1 6    ? 176.703 213.946 139.321 1.00 234.43 ? 24   PRO A O   1 
ATOM   10   C CB  . PRO A 1 6    ? 175.595 216.228 141.189 1.00 239.86 ? 24   PRO A CB  1 
ATOM   11   C CG  . PRO A 1 6    ? 175.875 217.041 139.985 1.00 238.76 ? 24   PRO A CG  1 
ATOM   12   C CD  . PRO A 1 6    ? 177.372 217.186 139.883 1.00 241.48 ? 24   PRO A CD  1 
ATOM   13   N N   . GLY A 1 7    ? 176.265 212.954 141.304 1.00 232.30 ? 25   GLY A N   1 
ATOM   14   C CA  . GLY A 1 7    ? 176.010 211.647 140.746 1.00 224.00 ? 25   GLY A CA  1 
ATOM   15   C C   . GLY A 1 7    ? 176.536 210.541 141.639 1.00 218.68 ? 25   GLY A C   1 
ATOM   16   O O   . GLY A 1 7    ? 177.055 210.792 142.731 1.00 215.97 ? 25   GLY A O   1 
ATOM   17   N N   . PRO A 1 8    ? 176.404 209.290 141.197 1.00 217.44 ? 26   PRO A N   1 
ATOM   18   C CA  . PRO A 1 8    ? 176.925 208.176 141.998 1.00 212.99 ? 26   PRO A CA  1 
ATOM   19   C C   . PRO A 1 8    ? 178.441 208.232 142.105 1.00 211.67 ? 26   PRO A C   1 
ATOM   20   O O   . PRO A 1 8    ? 179.133 208.625 141.164 1.00 216.40 ? 26   PRO A O   1 
ATOM   21   C CB  . PRO A 1 8    ? 176.459 206.935 141.228 1.00 211.86 ? 26   PRO A CB  1 
ATOM   22   C CG  . PRO A 1 8    ? 176.284 207.400 139.830 1.00 212.27 ? 26   PRO A CG  1 
ATOM   23   C CD  . PRO A 1 8    ? 175.838 208.830 139.916 1.00 215.65 ? 26   PRO A CD  1 
ATOM   24   N N   . ARG A 1 9    ? 178.947 207.823 143.267 1.00 206.06 ? 27   ARG A N   1 
ATOM   25   C CA  . ARG A 1 9    ? 180.370 207.858 143.590 1.00 203.20 ? 27   ARG A CA  1 
ATOM   26   C C   . ARG A 1 9    ? 180.950 206.491 143.907 1.00 192.37 ? 27   ARG A C   1 
ATOM   27   O O   . ARG A 1 9    ? 182.056 206.180 143.460 1.00 191.69 ? 27   ARG A O   1 
ATOM   28   C CB  . ARG A 1 9    ? 180.619 208.786 144.789 1.00 201.73 ? 27   ARG A CB  1 
ATOM   29   C CG  . ARG A 1 9    ? 180.192 210.230 144.577 1.00 206.05 ? 27   ARG A CG  1 
ATOM   30   C CD  . ARG A 1 9    ? 180.446 211.061 145.821 1.00 205.57 ? 27   ARG A CD  1 
ATOM   31   N NE  . ARG A 1 9    ? 181.858 211.399 145.963 1.00 209.00 ? 27   ARG A NE  1 
ATOM   32   C CZ  . ARG A 1 9    ? 182.377 212.110 146.957 1.00 212.01 ? 27   ARG A CZ  1 
ATOM   33   N NH1 . ARG A 1 9    ? 181.628 212.588 147.940 1.00 210.13 ? 27   ARG A NH1 1 
ATOM   34   N NH2 . ARG A 1 9    ? 183.686 212.347 146.968 1.00 216.17 ? 27   ARG A NH2 1 
ATOM   35   N N   . PHE A 1 10   ? 180.235 205.666 144.667 1.00 184.50 ? 28   PHE A N   1 
ATOM   36   C CA  . PHE A 1 10   ? 180.796 204.423 145.174 1.00 175.24 ? 28   PHE A CA  1 
ATOM   37   C C   . PHE A 1 10   ? 179.669 203.470 145.533 1.00 170.66 ? 28   PHE A C   1 
ATOM   38   O O   . PHE A 1 10   ? 178.506 203.865 145.650 1.00 175.08 ? 28   PHE A O   1 
ATOM   39   C CB  . PHE A 1 10   ? 181.680 204.674 146.399 1.00 172.66 ? 28   PHE A CB  1 
ATOM   40   C CG  . PHE A 1 10   ? 180.901 204.944 147.654 1.00 171.79 ? 28   PHE A CG  1 
ATOM   41   C CD1 . PHE A 1 10   ? 180.240 206.148 147.828 1.00 176.00 ? 28   PHE A CD1 1 
ATOM   42   C CD2 . PHE A 1 10   ? 180.824 203.994 148.656 1.00 167.82 ? 28   PHE A CD2 1 
ATOM   43   C CE1 . PHE A 1 10   ? 179.519 206.400 148.978 1.00 175.78 ? 28   PHE A CE1 1 
ATOM   44   C CE2 . PHE A 1 10   ? 180.104 204.240 149.809 1.00 169.76 ? 28   PHE A CE2 1 
ATOM   45   C CZ  . PHE A 1 10   ? 179.451 205.445 149.969 1.00 172.43 ? 28   PHE A CZ  1 
ATOM   46   N N   . LEU A 1 11   ? 180.038 202.204 145.709 1.00 162.48 ? 29   LEU A N   1 
ATOM   47   C CA  . LEU A 1 11   ? 179.106 201.187 146.187 1.00 155.63 ? 29   LEU A CA  1 
ATOM   48   C C   . LEU A 1 11   ? 179.926 200.064 146.796 1.00 149.91 ? 29   LEU A C   1 
ATOM   49   O O   . LEU A 1 11   ? 180.718 199.430 146.090 1.00 150.98 ? 29   LEU A O   1 
ATOM   50   C CB  . LEU A 1 11   ? 178.231 200.663 145.051 1.00 156.11 ? 29   LEU A CB  1 
ATOM   51   C CG  . LEU A 1 11   ? 177.206 199.600 145.454 1.00 153.89 ? 29   LEU A CG  1 
ATOM   52   C CD1 . LEU A 1 11   ? 175.818 199.978 144.966 1.00 160.80 ? 29   LEU A CD1 1 
ATOM   53   C CD2 . LEU A 1 11   ? 177.611 198.237 144.922 1.00 156.25 ? 29   LEU A CD2 1 
ATOM   54   N N   . VAL A 1 12   ? 179.745 199.822 148.094 1.00 145.88 ? 30   VAL A N   1 
ATOM   55   C CA  . VAL A 1 12   ? 180.470 198.780 148.814 1.00 142.94 ? 30   VAL A CA  1 
ATOM   56   C C   . VAL A 1 12   ? 179.459 197.847 149.461 1.00 141.26 ? 30   VAL A C   1 
ATOM   57   O O   . VAL A 1 12   ? 178.520 198.301 150.123 1.00 146.66 ? 30   VAL A O   1 
ATOM   58   C CB  . VAL A 1 12   ? 181.438 199.360 149.864 1.00 149.51 ? 30   VAL A CB  1 
ATOM   59   C CG1 . VAL A 1 12   ? 182.707 199.851 149.195 1.00 157.81 ? 30   VAL A CG1 1 
ATOM   60   C CG2 . VAL A 1 12   ? 180.795 200.484 150.647 1.00 151.38 ? 30   VAL A CG2 1 
ATOM   61   N N   . THR A 1 13   ? 179.655 196.546 149.268 1.00 137.95 ? 31   THR A N   1 
ATOM   62   C CA  . THR A 1 13   ? 178.771 195.514 149.792 1.00 138.06 ? 31   THR A CA  1 
ATOM   63   C C   . THR A 1 13   ? 179.566 194.574 150.684 1.00 135.47 ? 31   THR A C   1 
ATOM   64   O O   . THR A 1 13   ? 180.757 194.349 150.455 1.00 136.27 ? 31   THR A O   1 
ATOM   65   C CB  . THR A 1 13   ? 178.107 194.716 148.666 1.00 142.37 ? 31   THR A CB  1 
ATOM   66   O OG1 . THR A 1 13   ? 178.963 193.637 148.273 1.00 146.08 ? 31   THR A OG1 1 
ATOM   67   C CG2 . THR A 1 13   ? 177.819 195.605 147.462 1.00 146.42 ? 31   THR A CG2 1 
ATOM   68   N N   . ALA A 1 14   ? 178.903 194.044 151.713 1.00 134.22 ? 32   ALA A N   1 
ATOM   69   C CA  . ALA A 1 14   ? 179.507 193.096 152.635 1.00 130.39 ? 32   ALA A CA  1 
ATOM   70   C C   . ALA A 1 14   ? 178.474 192.045 153.019 1.00 130.07 ? 32   ALA A C   1 
ATOM   71   O O   . ALA A 1 14   ? 177.267 192.308 152.920 1.00 137.27 ? 32   ALA A O   1 
ATOM   72   C CB  . ALA A 1 14   ? 180.026 193.792 153.899 1.00 128.94 ? 32   ALA A CB  1 
ATOM   73   N N   . PRO A 1 15   ? 178.893 190.851 153.444 1.00 124.13 ? 33   PRO A N   1 
ATOM   74   C CA  . PRO A 1 15   ? 177.915 189.899 153.979 1.00 123.67 ? 33   PRO A CA  1 
ATOM   75   C C   . PRO A 1 15   ? 177.547 190.264 155.406 1.00 125.44 ? 33   PRO A C   1 
ATOM   76   O O   . PRO A 1 15   ? 178.374 190.766 156.171 1.00 122.81 ? 33   PRO A O   1 
ATOM   77   C CB  . PRO A 1 15   ? 178.637 188.549 153.906 1.00 120.41 ? 33   PRO A CB  1 
ATOM   78   C CG  . PRO A 1 15   ? 180.086 188.860 153.770 1.00 126.48 ? 33   PRO A CG  1 
ATOM   79   C CD  . PRO A 1 15   ? 180.268 190.331 153.547 1.00 128.57 ? 33   PRO A CD  1 
ATOM   80   N N   . GLY A 1 16   ? 176.294 190.008 155.762 1.00 131.50 ? 34   GLY A N   1 
ATOM   81   C CA  . GLY A 1 16   ? 175.793 190.381 157.066 1.00 130.33 ? 34   GLY A CA  1 
ATOM   82   C C   . GLY A 1 16   ? 176.139 189.444 158.198 1.00 134.07 ? 34   GLY A C   1 
ATOM   83   O O   . GLY A 1 16   ? 175.758 189.725 159.338 1.00 139.49 ? 34   GLY A O   1 
ATOM   84   N N   . ILE A 1 17   ? 176.853 188.352 157.926 1.00 129.29 ? 35   ILE A N   1 
ATOM   85   C CA  . ILE A 1 17   ? 177.152 187.331 158.921 1.00 128.94 ? 35   ILE A CA  1 
ATOM   86   C C   . ILE A 1 17   ? 178.649 187.318 159.207 1.00 128.44 ? 35   ILE A C   1 
ATOM   87   O O   . ILE A 1 17   ? 179.463 187.857 158.452 1.00 129.89 ? 35   ILE A O   1 
ATOM   88   C CB  . ILE A 1 17   ? 176.630 185.940 158.475 1.00 129.68 ? 35   ILE A CB  1 
ATOM   89   C CG1 . ILE A 1 17   ? 177.478 185.274 157.367 1.00 130.97 ? 35   ILE A CG1 1 
ATOM   90   C CG2 . ILE A 1 17   ? 175.185 186.066 158.004 1.00 130.84 ? 35   ILE A CG2 1 
ATOM   91   C CD1 . ILE A 1 17   ? 177.118 183.822 157.141 1.00 136.91 ? 35   ILE A CD1 1 
ATOM   92   N N   . ILE A 1 18   ? 179.002 186.689 160.327 1.00 129.41 ? 36   ILE A N   1 
ATOM   93   C CA  . ILE A 1 18   ? 180.385 186.412 160.697 1.00 122.65 ? 36   ILE A CA  1 
ATOM   94   C C   . ILE A 1 18   ? 180.459 184.941 161.078 1.00 123.71 ? 36   ILE A C   1 
ATOM   95   O O   . ILE A 1 18   ? 179.592 184.442 161.803 1.00 127.77 ? 36   ILE A O   1 
ATOM   96   C CB  . ILE A 1 18   ? 180.873 187.320 161.850 1.00 122.12 ? 36   ILE A CB  1 
ATOM   97   C CG1 . ILE A 1 18   ? 182.321 187.011 162.264 1.00 120.12 ? 36   ILE A CG1 1 
ATOM   98   C CG2 . ILE A 1 18   ? 179.964 187.214 163.080 1.00 134.53 ? 36   ILE A CG2 1 
ATOM   99   C CD1 . ILE A 1 18   ? 183.342 187.181 161.161 1.00 117.43 ? 36   ILE A CD1 1 
ATOM   100  N N   . ARG A 1 19   ? 181.484 184.252 160.577 1.00 121.72 ? 37   ARG A N   1 
ATOM   101  C CA  . ARG A 1 19   ? 181.673 182.825 160.788 1.00 121.85 ? 37   ARG A CA  1 
ATOM   102  C C   . ARG A 1 19   ? 183.128 182.597 161.189 1.00 121.77 ? 37   ARG A C   1 
ATOM   103  O O   . ARG A 1 19   ? 184.031 183.101 160.500 1.00 129.54 ? 37   ARG A O   1 
ATOM   104  C CB  . ARG A 1 19   ? 181.338 182.048 159.510 1.00 123.28 ? 37   ARG A CB  1 
ATOM   105  C CG  . ARG A 1 19   ? 181.216 180.547 159.698 1.00 121.85 ? 37   ARG A CG  1 
ATOM   106  C CD  . ARG A 1 19   ? 181.172 179.829 158.362 1.00 118.28 ? 37   ARG A CD  1 
ATOM   107  N NE  . ARG A 1 19   ? 179.963 180.152 157.612 1.00 110.37 ? 37   ARG A NE  1 
ATOM   108  C CZ  . ARG A 1 19   ? 178.764 179.628 157.833 1.00 120.42 ? 37   ARG A CZ  1 
ATOM   109  N NH1 . ARG A 1 19   ? 178.553 178.743 158.797 1.00 122.69 ? 37   ARG A NH1 1 
ATOM   110  N NH2 . ARG A 1 19   ? 177.744 180.002 157.067 1.00 125.03 ? 37   ARG A NH2 1 
ATOM   111  N N   . PRO A 1 20   ? 183.418 181.873 162.278 1.00 117.76 ? 38   PRO A N   1 
ATOM   112  C CA  . PRO A 1 20   ? 184.828 181.577 162.577 1.00 123.36 ? 38   PRO A CA  1 
ATOM   113  C C   . PRO A 1 20   ? 185.438 180.707 161.489 1.00 127.98 ? 38   PRO A C   1 
ATOM   114  O O   . PRO A 1 20   ? 184.834 179.730 161.043 1.00 128.58 ? 38   PRO A O   1 
ATOM   115  C CB  . PRO A 1 20   ? 184.770 180.846 163.924 1.00 127.49 ? 38   PRO A CB  1 
ATOM   116  C CG  . PRO A 1 20   ? 183.446 181.160 164.484 1.00 129.00 ? 38   PRO A CG  1 
ATOM   117  C CD  . PRO A 1 20   ? 182.538 181.313 163.320 1.00 123.80 ? 38   PRO A CD  1 
ATOM   118  N N   . GLY A 1 21   ? 186.642 181.075 161.062 1.00 130.73 ? 39   GLY A N   1 
ATOM   119  C CA  . GLY A 1 21   ? 187.258 180.441 159.918 1.00 129.28 ? 39   GLY A CA  1 
ATOM   120  C C   . GLY A 1 21   ? 186.710 180.883 158.581 1.00 133.50 ? 39   GLY A C   1 
ATOM   121  O O   . GLY A 1 21   ? 187.148 180.359 157.550 1.00 137.97 ? 39   GLY A O   1 
ATOM   122  N N   . GLY A 1 22   ? 185.775 181.831 158.561 1.00 135.78 ? 40   GLY A N   1 
ATOM   123  C CA  . GLY A 1 22   ? 185.211 182.361 157.333 1.00 137.37 ? 40   GLY A CA  1 
ATOM   124  C C   . GLY A 1 22   ? 185.848 183.700 157.004 1.00 142.23 ? 40   GLY A C   1 
ATOM   125  O O   . GLY A 1 22   ? 185.940 184.582 157.859 1.00 147.53 ? 40   GLY A O   1 
ATOM   126  N N   . ASN A 1 23   ? 186.282 183.834 155.756 1.00 137.41 ? 41   ASN A N   1 
ATOM   127  C CA  . ASN A 1 23   ? 186.995 185.022 155.305 1.00 137.38 ? 41   ASN A CA  1 
ATOM   128  C C   . ASN A 1 23   ? 185.972 186.107 154.995 1.00 140.80 ? 41   ASN A C   1 
ATOM   129  O O   . ASN A 1 23   ? 185.180 185.975 154.057 1.00 142.00 ? 41   ASN A O   1 
ATOM   130  C CB  . ASN A 1 23   ? 187.849 184.690 154.086 1.00 138.64 ? 41   ASN A CB  1 
ATOM   131  C CG  . ASN A 1 23   ? 189.109 183.944 154.457 1.00 147.84 ? 41   ASN A CG  1 
ATOM   132  O OD1 . ASN A 1 23   ? 189.092 183.093 155.344 1.00 150.82 ? 41   ASN A OD1 1 
ATOM   133  N ND2 . ASN A 1 23   ? 190.205 184.238 153.772 1.00 155.60 ? 41   ASN A ND2 1 
ATOM   134  N N   . VAL A 1 24   ? 185.988 187.179 155.784 1.00 140.81 ? 42   VAL A N   1 
ATOM   135  C CA  . VAL A 1 24   ? 185.034 188.274 155.621 1.00 135.79 ? 42   VAL A CA  1 
ATOM   136  C C   . VAL A 1 24   ? 185.509 189.102 154.432 1.00 137.15 ? 42   VAL A C   1 
ATOM   137  O O   . VAL A 1 24   ? 186.377 189.965 154.568 1.00 144.52 ? 42   VAL A O   1 
ATOM   138  C CB  . VAL A 1 24   ? 184.906 189.121 156.889 1.00 135.91 ? 42   VAL A CB  1 
ATOM   139  C CG1 . VAL A 1 24   ? 183.708 190.059 156.783 1.00 130.22 ? 42   VAL A CG1 1 
ATOM   140  C CG2 . VAL A 1 24   ? 184.777 188.230 158.118 1.00 141.59 ? 42   VAL A CG2 1 
ATOM   141  N N   . THR A 1 25   ? 184.935 188.839 153.261 1.00 130.16 ? 43   THR A N   1 
ATOM   142  C CA  . THR A 1 25   ? 185.299 189.505 152.017 1.00 131.70 ? 43   THR A CA  1 
ATOM   143  C C   . THR A 1 25   ? 184.211 190.510 151.671 1.00 131.31 ? 43   THR A C   1 
ATOM   144  O O   . THR A 1 25   ? 183.029 190.152 151.623 1.00 127.07 ? 43   THR A O   1 
ATOM   145  C CB  . THR A 1 25   ? 185.473 188.490 150.886 1.00 131.07 ? 43   THR A CB  1 
ATOM   146  O OG1 . THR A 1 25   ? 186.637 187.693 151.133 1.00 132.58 ? 43   THR A OG1 1 
ATOM   147  C CG2 . THR A 1 25   ? 185.627 189.193 149.544 1.00 131.47 ? 43   THR A CG2 1 
ATOM   148  N N   . ILE A 1 26   ? 184.613 191.757 151.434 1.00 134.53 ? 44   ILE A N   1 
ATOM   149  C CA  . ILE A 1 26   ? 183.710 192.825 151.025 1.00 130.86 ? 44   ILE A CA  1 
ATOM   150  C C   . ILE A 1 26   ? 184.048 193.213 149.595 1.00 133.01 ? 44   ILE A C   1 
ATOM   151  O O   . ILE A 1 26   ? 185.209 193.171 149.179 1.00 137.76 ? 44   ILE A O   1 
ATOM   152  C CB  . ILE A 1 26   ? 183.796 194.041 151.977 1.00 126.93 ? 44   ILE A CB  1 
ATOM   153  C CG1 . ILE A 1 26   ? 185.212 194.634 152.028 1.00 126.11 ? 44   ILE A CG1 1 
ATOM   154  C CG2 . ILE A 1 26   ? 183.367 193.640 153.379 1.00 130.54 ? 44   ILE A CG2 1 
ATOM   155  C CD1 . ILE A 1 26   ? 185.312 195.869 152.892 1.00 135.75 ? 44   ILE A CD1 1 
ATOM   156  N N   . GLY A 1 27   ? 183.023 193.589 148.840 1.00 131.29 ? 45   GLY A N   1 
ATOM   157  C CA  . GLY A 1 27   ? 183.176 194.038 147.463 1.00 133.36 ? 45   GLY A CA  1 
ATOM   158  C C   . GLY A 1 27   ? 183.099 195.553 147.408 1.00 138.17 ? 45   GLY A C   1 
ATOM   159  O O   . GLY A 1 27   ? 182.301 196.163 148.123 1.00 143.09 ? 45   GLY A O   1 
ATOM   160  N N   . VAL A 1 28   ? 183.936 196.148 146.560 1.00 139.22 ? 46   VAL A N   1 
ATOM   161  C CA  . VAL A 1 28   ? 184.039 197.594 146.402 1.00 144.90 ? 46   VAL A CA  1 
ATOM   162  C C   . VAL A 1 28   ? 183.957 197.923 144.919 1.00 150.26 ? 46   VAL A C   1 
ATOM   163  O O   . VAL A 1 28   ? 184.604 197.262 144.095 1.00 149.88 ? 46   VAL A O   1 
ATOM   164  C CB  . VAL A 1 28   ? 185.342 198.146 147.015 1.00 147.98 ? 46   VAL A CB  1 
ATOM   165  C CG1 . VAL A 1 28   ? 186.585 197.513 146.372 1.00 148.51 ? 46   VAL A CG1 1 
ATOM   166  C CG2 . VAL A 1 28   ? 185.395 199.661 146.876 1.00 154.75 ? 46   VAL A CG2 1 
ATOM   167  N N   . GLU A 1 29   ? 183.169 198.947 144.585 1.00 155.51 ? 47   GLU A N   1 
ATOM   168  C CA  . GLU A 1 29   ? 183.025 199.418 143.216 1.00 159.59 ? 47   GLU A CA  1 
ATOM   169  C C   . GLU A 1 29   ? 183.011 200.938 143.218 1.00 166.55 ? 47   GLU A C   1 
ATOM   170  O O   . GLU A 1 29   ? 182.299 201.553 144.017 1.00 167.28 ? 47   GLU A O   1 
ATOM   171  C CB  . GLU A 1 29   ? 181.738 198.880 142.582 1.00 158.87 ? 47   GLU A CB  1 
ATOM   172  C CG  . GLU A 1 29   ? 181.512 199.346 141.149 1.00 166.05 ? 47   GLU A CG  1 
ATOM   173  C CD  . GLU A 1 29   ? 180.541 198.473 140.366 1.00 165.99 ? 47   GLU A CD  1 
ATOM   174  O OE1 . GLU A 1 29   ? 180.105 197.421 140.881 1.00 162.90 ? 47   GLU A OE1 1 
ATOM   175  O OE2 . GLU A 1 29   ? 180.209 198.845 139.221 1.00 166.15 ? 47   GLU A OE2 1 
ATOM   176  N N   . LEU A 1 30   ? 183.810 201.534 142.336 1.00 171.47 ? 48   LEU A N   1 
ATOM   177  C CA  . LEU A 1 30   ? 183.856 202.977 142.135 1.00 180.17 ? 48   LEU A CA  1 
ATOM   178  C C   . LEU A 1 30   ? 183.734 203.237 140.641 1.00 183.59 ? 48   LEU A C   1 
ATOM   179  O O   . LEU A 1 30   ? 184.482 202.652 139.851 1.00 183.21 ? 48   LEU A O   1 
ATOM   180  C CB  . LEU A 1 30   ? 185.156 203.566 142.683 1.00 182.94 ? 48   LEU A CB  1 
ATOM   181  C CG  . LEU A 1 30   ? 185.604 203.072 144.060 1.00 177.91 ? 48   LEU A CG  1 
ATOM   182  C CD1 . LEU A 1 30   ? 186.687 202.013 143.920 1.00 175.86 ? 48   LEU A CD1 1 
ATOM   183  C CD2 . LEU A 1 30   ? 186.101 204.232 144.905 1.00 182.31 ? 48   LEU A CD2 1 
ATOM   184  N N   . LEU A 1 31   ? 182.810 204.120 140.255 1.00 187.75 ? 49   LEU A N   1 
ATOM   185  C CA  . LEU A 1 31   ? 182.281 204.116 138.896 1.00 193.38 ? 49   LEU A CA  1 
ATOM   186  C C   . LEU A 1 31   ? 182.681 205.339 138.078 1.00 200.55 ? 49   LEU A C   1 
ATOM   187  O O   . LEU A 1 31   ? 183.360 205.180 137.059 1.00 200.74 ? 49   LEU A O   1 
ATOM   188  C CB  . LEU A 1 31   ? 180.749 203.995 138.961 1.00 190.58 ? 49   LEU A CB  1 
ATOM   189  C CG  . LEU A 1 31   ? 180.210 202.957 139.956 1.00 182.13 ? 49   LEU A CG  1 
ATOM   190  C CD1 . LEU A 1 31   ? 179.821 203.605 141.286 1.00 179.14 ? 49   LEU A CD1 1 
ATOM   191  C CD2 . LEU A 1 31   ? 179.034 202.187 139.379 1.00 181.37 ? 49   LEU A CD2 1 
ATOM   192  N N   . GLU A 1 32   ? 182.279 206.558 138.483 1.00 207.57 ? 50   GLU A N   1 
ATOM   193  C CA  . GLU A 1 32   ? 182.584 207.767 137.713 1.00 216.35 ? 50   GLU A CA  1 
ATOM   194  C C   . GLU A 1 32   ? 183.109 208.922 138.551 1.00 220.11 ? 50   GLU A C   1 
ATOM   195  O O   . GLU A 1 32   ? 184.037 209.609 138.117 1.00 219.62 ? 50   GLU A O   1 
ATOM   196  C CB  . GLU A 1 32   ? 181.319 208.214 136.953 1.00 221.50 ? 50   GLU A CB  1 
ATOM   197  C CG  . GLU A 1 32   ? 181.565 209.251 135.857 1.00 225.15 ? 50   GLU A CG  1 
ATOM   198  C CD  . GLU A 1 32   ? 180.281 209.865 135.333 1.00 231.36 ? 50   GLU A CD  1 
ATOM   199  O OE1 . GLU A 1 32   ? 179.191 209.390 135.717 1.00 235.00 ? 50   GLU A OE1 1 
ATOM   200  O OE2 . GLU A 1 32   ? 180.361 210.824 134.538 1.00 232.76 ? 50   GLU A OE2 1 
ATOM   201  N N   . HIS A 1 33   ? 182.554 209.145 139.741 1.00 223.33 ? 51   HIS A N   1 
ATOM   202  C CA  . HIS A 1 33   ? 182.774 210.374 140.495 1.00 227.15 ? 51   HIS A CA  1 
ATOM   203  C C   . HIS A 1 33   ? 183.767 210.211 141.640 1.00 224.88 ? 51   HIS A C   1 
ATOM   204  O O   . HIS A 1 33   ? 183.920 211.134 142.446 1.00 223.09 ? 51   HIS A O   1 
ATOM   205  C CB  . HIS A 1 33   ? 181.439 210.892 141.032 1.00 226.51 ? 51   HIS A CB  1 
ATOM   206  C CG  . HIS A 1 33   ? 180.439 211.200 139.962 1.00 229.32 ? 51   HIS A CG  1 
ATOM   207  N ND1 . HIS A 1 33   ? 179.607 210.242 139.423 1.00 227.57 ? 51   HIS A ND1 1 
ATOM   208  C CD2 . HIS A 1 33   ? 180.134 212.359 139.333 1.00 232.17 ? 51   HIS A CD2 1 
ATOM   209  C CE1 . HIS A 1 33   ? 178.837 210.797 138.505 1.00 228.17 ? 51   HIS A CE1 1 
ATOM   210  N NE2 . HIS A 1 33   ? 179.135 212.082 138.432 1.00 230.76 ? 51   HIS A NE2 1 
ATOM   211  N N   . CYS A 1 34   ? 184.444 209.070 141.731 1.00 224.26 ? 52   CYS A N   1 
ATOM   212  C CA  . CYS A 1 34   ? 185.432 208.869 142.771 1.00 226.49 ? 52   CYS A CA  1 
ATOM   213  C C   . CYS A 1 34   ? 186.719 209.623 142.436 1.00 228.27 ? 52   CYS A C   1 
ATOM   214  O O   . CYS A 1 34   ? 186.938 210.009 141.285 1.00 226.06 ? 52   CYS A O   1 
ATOM   215  C CB  . CYS A 1 34   ? 185.735 207.384 142.920 1.00 220.02 ? 52   CYS A CB  1 
ATOM   216  S SG  . CYS A 1 34   ? 186.334 206.651 141.386 1.00 214.93 ? 52   CYS A SG  1 
ATOM   217  N N   . PRO A 1 35   ? 187.599 209.851 143.430 1.00 227.48 ? 53   PRO A N   1 
ATOM   218  C CA  . PRO A 1 35   ? 188.956 210.309 143.096 1.00 225.02 ? 53   PRO A CA  1 
ATOM   219  C C   . PRO A 1 35   ? 189.771 209.218 142.418 1.00 222.68 ? 53   PRO A C   1 
ATOM   220  O O   . PRO A 1 35   ? 189.273 208.111 142.195 1.00 220.54 ? 53   PRO A O   1 
ATOM   221  C CB  . PRO A 1 35   ? 189.550 210.692 144.457 1.00 222.79 ? 53   PRO A CB  1 
ATOM   222  C CG  . PRO A 1 35   ? 188.382 210.921 145.338 1.00 222.74 ? 53   PRO A CG  1 
ATOM   223  C CD  . PRO A 1 35   ? 187.343 209.953 144.878 1.00 224.33 ? 53   PRO A CD  1 
ATOM   224  N N   . SER A 1 36   ? 191.030 209.519 142.092 1.00 224.22 ? 54   SER A N   1 
ATOM   225  C CA  . SER A 1 36   ? 191.860 208.561 141.368 1.00 223.63 ? 54   SER A CA  1 
ATOM   226  C C   . SER A 1 36   ? 192.119 207.309 142.199 1.00 218.08 ? 54   SER A C   1 
ATOM   227  O O   . SER A 1 36   ? 192.015 206.186 141.693 1.00 213.52 ? 54   SER A O   1 
ATOM   228  C CB  . SER A 1 36   ? 193.180 209.217 140.964 1.00 224.57 ? 54   SER A CB  1 
ATOM   229  O OG  . SER A 1 36   ? 193.921 209.612 142.104 1.00 225.08 ? 54   SER A OG  1 
ATOM   230  N N   . GLN A 1 37   ? 192.460 207.486 143.476 1.00 216.71 ? 55   GLN A N   1 
ATOM   231  C CA  . GLN A 1 37   ? 192.781 206.390 144.384 1.00 210.50 ? 55   GLN A CA  1 
ATOM   232  C C   . GLN A 1 37   ? 191.958 206.543 145.652 1.00 204.47 ? 55   GLN A C   1 
ATOM   233  O O   . GLN A 1 37   ? 191.829 207.654 146.178 1.00 206.75 ? 55   GLN A O   1 
ATOM   234  C CB  . GLN A 1 37   ? 194.276 206.369 144.727 1.00 213.22 ? 55   GLN A CB  1 
ATOM   235  C CG  . GLN A 1 37   ? 195.198 206.171 143.527 1.00 214.40 ? 55   GLN A CG  1 
ATOM   236  C CD  . GLN A 1 37   ? 195.248 204.730 143.055 1.00 211.30 ? 55   GLN A CD  1 
ATOM   237  O OE1 . GLN A 1 37   ? 194.613 203.850 143.635 1.00 207.95 ? 55   GLN A OE1 1 
ATOM   238  N NE2 . GLN A 1 37   ? 196.007 204.483 141.994 1.00 213.31 ? 55   GLN A NE2 1 
ATOM   239  N N   . VAL A 1 38   ? 191.400 205.433 146.133 1.00 198.85 ? 56   VAL A N   1 
ATOM   240  C CA  . VAL A 1 38   ? 190.596 205.410 147.351 1.00 195.54 ? 56   VAL A CA  1 
ATOM   241  C C   . VAL A 1 38   ? 191.085 204.252 148.208 1.00 187.96 ? 56   VAL A C   1 
ATOM   242  O O   . VAL A 1 38   ? 191.163 203.115 147.730 1.00 184.02 ? 56   VAL A O   1 
ATOM   243  C CB  . VAL A 1 38   ? 189.094 205.267 147.044 1.00 198.37 ? 56   VAL A CB  1 
ATOM   244  C CG1 . VAL A 1 38   ? 188.302 204.963 148.315 1.00 196.81 ? 56   VAL A CG1 1 
ATOM   245  C CG2 . VAL A 1 38   ? 188.572 206.528 146.369 1.00 203.07 ? 56   VAL A CG2 1 
ATOM   246  N N   . THR A 1 39   ? 191.405 204.538 149.467 1.00 186.75 ? 57   THR A N   1 
ATOM   247  C CA  . THR A 1 39   ? 191.863 203.532 150.416 1.00 182.93 ? 57   THR A CA  1 
ATOM   248  C C   . THR A 1 39   ? 190.690 203.124 151.298 1.00 181.91 ? 57   THR A C   1 
ATOM   249  O O   . THR A 1 39   ? 190.124 203.961 152.007 1.00 185.25 ? 57   THR A O   1 
ATOM   250  C CB  . THR A 1 39   ? 193.013 204.070 151.268 1.00 183.21 ? 57   THR A CB  1 
ATOM   251  O OG1 . THR A 1 39   ? 194.013 204.642 150.416 1.00 188.29 ? 57   THR A OG1 1 
ATOM   252  C CG2 . THR A 1 39   ? 193.638 202.957 152.101 1.00 174.95 ? 57   THR A CG2 1 
ATOM   253  N N   . VAL A 1 40   ? 190.332 201.844 151.252 1.00 176.10 ? 58   VAL A N   1 
ATOM   254  C CA  . VAL A 1 40   ? 189.234 201.285 152.030 1.00 170.08 ? 58   VAL A CA  1 
ATOM   255  C C   . VAL A 1 40   ? 189.837 200.446 153.145 1.00 162.85 ? 58   VAL A C   1 
ATOM   256  O O   . VAL A 1 40   ? 190.681 199.577 152.887 1.00 161.39 ? 58   VAL A O   1 
ATOM   257  C CB  . VAL A 1 40   ? 188.294 200.441 151.152 1.00 171.09 ? 58   VAL A CB  1 
ATOM   258  C CG1 . VAL A 1 40   ? 187.071 199.991 151.952 1.00 168.39 ? 58   VAL A CG1 1 
ATOM   259  C CG2 . VAL A 1 40   ? 187.880 201.225 149.910 1.00 176.61 ? 58   VAL A CG2 1 
ATOM   260  N N   . LYS A 1 41   ? 189.405 200.711 154.377 1.00 160.25 ? 59   LYS A N   1 
ATOM   261  C CA  . LYS A 1 41   ? 189.847 199.994 155.564 1.00 160.00 ? 59   LYS A CA  1 
ATOM   262  C C   . LYS A 1 41   ? 188.655 199.279 156.180 1.00 159.76 ? 59   LYS A C   1 
ATOM   263  O O   . LYS A 1 41   ? 187.599 199.888 156.395 1.00 162.74 ? 59   LYS A O   1 
ATOM   264  C CB  . LYS A 1 41   ? 190.472 200.949 156.585 1.00 164.82 ? 59   LYS A CB  1 
ATOM   265  C CG  . LYS A 1 41   ? 191.173 200.247 157.738 1.00 167.49 ? 59   LYS A CG  1 
ATOM   266  C CD  . LYS A 1 41   ? 191.842 201.239 158.675 1.00 171.65 ? 59   LYS A CD  1 
ATOM   267  C CE  . LYS A 1 41   ? 192.625 200.528 159.767 1.00 173.97 ? 59   LYS A CE  1 
ATOM   268  N NZ  . LYS A 1 41   ? 193.185 201.478 160.768 1.00 178.28 ? 59   LYS A NZ  1 
ATOM   269  N N   . ALA A 1 42   ? 188.832 197.990 156.458 1.00 155.84 ? 60   ALA A N   1 
ATOM   270  C CA  . ALA A 1 42   ? 187.835 197.156 157.113 1.00 156.16 ? 60   ALA A CA  1 
ATOM   271  C C   . ALA A 1 42   ? 188.351 196.767 158.490 1.00 159.03 ? 60   ALA A C   1 
ATOM   272  O O   . ALA A 1 42   ? 189.499 196.326 158.624 1.00 159.28 ? 60   ALA A O   1 
ATOM   273  C CB  . ALA A 1 42   ? 187.535 195.906 156.286 1.00 152.08 ? 60   ALA A CB  1 
ATOM   274  N N   . GLU A 1 43   ? 187.506 196.942 159.505 1.00 162.80 ? 61   GLU A N   1 
ATOM   275  C CA  . GLU A 1 43   ? 187.846 196.659 160.892 1.00 160.58 ? 61   GLU A CA  1 
ATOM   276  C C   . GLU A 1 43   ? 186.764 195.792 161.516 1.00 156.29 ? 61   GLU A C   1 
ATOM   277  O O   . GLU A 1 43   ? 185.572 196.001 161.271 1.00 157.31 ? 61   GLU A O   1 
ATOM   278  C CB  . GLU A 1 43   ? 187.996 197.953 161.698 1.00 168.21 ? 61   GLU A CB  1 
ATOM   279  C CG  . GLU A 1 43   ? 188.919 198.981 161.064 1.00 172.57 ? 61   GLU A CG  1 
ATOM   280  C CD  . GLU A 1 43   ? 189.191 200.161 161.977 1.00 179.16 ? 61   GLU A CD  1 
ATOM   281  O OE1 . GLU A 1 43   ? 188.256 200.600 162.679 1.00 173.94 ? 61   GLU A OE1 1 
ATOM   282  O OE2 . GLU A 1 43   ? 190.340 200.649 161.993 1.00 183.41 ? 61   GLU A OE2 1 
ATOM   283  N N   . LEU A 1 44   ? 187.189 194.817 162.315 1.00 155.48 ? 62   LEU A N   1 
ATOM   284  C CA  . LEU A 1 44   ? 186.293 193.970 163.092 1.00 156.66 ? 62   LEU A CA  1 
ATOM   285  C C   . LEU A 1 44   ? 186.450 194.317 164.565 1.00 164.78 ? 62   LEU A C   1 
ATOM   286  O O   . LEU A 1 44   ? 187.572 194.344 165.083 1.00 170.42 ? 62   LEU A O   1 
ATOM   287  C CB  . LEU A 1 44   ? 186.591 192.489 162.859 1.00 149.53 ? 62   LEU A CB  1 
ATOM   288  C CG  . LEU A 1 44   ? 185.407 191.562 163.138 1.00 142.50 ? 62   LEU A CG  1 
ATOM   289  C CD1 . LEU A 1 44   ? 184.495 191.484 161.926 1.00 142.04 ? 62   LEU A CD1 1 
ATOM   290  C CD2 . LEU A 1 44   ? 185.881 190.177 163.542 1.00 143.55 ? 62   LEU A CD2 1 
ATOM   291  N N   . LEU A 1 45   ? 185.327 194.574 165.231 1.00 162.11 ? 63   LEU A N   1 
ATOM   292  C CA  . LEU A 1 45   ? 185.289 195.018 166.616 1.00 163.97 ? 63   LEU A CA  1 
ATOM   293  C C   . LEU A 1 45   ? 184.468 194.034 167.434 1.00 166.02 ? 63   LEU A C   1 
ATOM   294  O O   . LEU A 1 45   ? 183.445 193.526 166.964 1.00 162.34 ? 63   LEU A O   1 
ATOM   295  C CB  . LEU A 1 45   ? 184.688 196.425 166.736 1.00 167.39 ? 63   LEU A CB  1 
ATOM   296  C CG  . LEU A 1 45   ? 185.026 197.447 165.643 1.00 168.59 ? 63   LEU A CG  1 
ATOM   297  C CD1 . LEU A 1 45   ? 184.197 198.706 165.825 1.00 172.25 ? 63   LEU A CD1 1 
ATOM   298  C CD2 . LEU A 1 45   ? 186.510 197.775 165.646 1.00 167.32 ? 63   LEU A CD2 1 
ATOM   299  N N   . LYS A 1 46   ? 184.917 193.792 168.665 1.00 173.18 ? 64   LYS A N   1 
ATOM   300  C CA  . LYS A 1 46   ? 184.324 192.802 169.556 1.00 174.36 ? 64   LYS A CA  1 
ATOM   301  C C   . LYS A 1 46   ? 183.696 193.490 170.760 1.00 179.82 ? 64   LYS A C   1 
ATOM   302  O O   . LYS A 1 46   ? 183.887 193.058 171.902 1.00 180.55 ? 64   LYS A O   1 
ATOM   303  C CB  . LYS A 1 46   ? 185.381 191.789 170.000 1.00 174.17 ? 64   LYS A CB  1 
ATOM   304  C CG  . LYS A 1 46   ? 184.810 190.448 170.432 1.00 170.96 ? 64   LYS A CG  1 
ATOM   305  C CD  . LYS A 1 46   ? 185.762 189.686 171.353 1.00 173.65 ? 64   LYS A CD  1 
ATOM   306  C CE  . LYS A 1 46   ? 187.025 189.212 170.638 1.00 176.64 ? 64   LYS A CE  1 
ATOM   307  N NZ  . LYS A 1 46   ? 186.745 188.296 169.496 1.00 176.07 ? 64   LYS A NZ  1 
ATOM   308  N N   . THR A 1 47   ? 182.954 194.570 170.504 1.00 182.71 ? 65   THR A N   1 
ATOM   309  C CA  . THR A 1 47   ? 182.373 195.403 171.552 1.00 191.83 ? 65   THR A CA  1 
ATOM   310  C C   . THR A 1 47   ? 181.489 194.606 172.502 1.00 194.85 ? 65   THR A C   1 
ATOM   311  O O   . THR A 1 47   ? 180.424 194.117 172.115 1.00 190.07 ? 65   THR A O   1 
ATOM   312  C CB  . THR A 1 47   ? 181.565 196.543 170.928 1.00 191.89 ? 65   THR A CB  1 
ATOM   313  O OG1 . THR A 1 47   ? 182.416 197.330 170.085 1.00 189.54 ? 65   THR A OG1 1 
ATOM   314  C CG2 . THR A 1 47   ? 180.959 197.431 172.007 1.00 193.17 ? 65   THR A CG2 1 
ATOM   315  N N   . ALA A 1 48   ? 181.933 194.476 173.750 1.00 201.81 ? 66   ALA A N   1 
ATOM   316  C CA  . ALA A 1 48   ? 181.173 193.792 174.787 1.00 203.80 ? 66   ALA A CA  1 
ATOM   317  C C   . ALA A 1 48   ? 181.538 194.407 176.128 1.00 208.44 ? 66   ALA A C   1 
ATOM   318  O O   . ALA A 1 48   ? 182.724 194.550 176.441 1.00 208.12 ? 66   ALA A O   1 
ATOM   319  C CB  . ALA A 1 48   ? 181.461 192.287 174.789 1.00 196.05 ? 66   ALA A CB  1 
ATOM   320  N N   . SER A 1 49   ? 180.521 194.764 176.912 1.00 209.34 ? 67   SER A N   1 
ATOM   321  C CA  . SER A 1 49   ? 180.721 195.420 178.204 1.00 207.29 ? 67   SER A CA  1 
ATOM   322  C C   . SER A 1 49   ? 181.484 196.732 178.039 1.00 209.34 ? 67   SER A C   1 
ATOM   323  O O   . SER A 1 49   ? 182.335 197.089 178.856 1.00 206.61 ? 67   SER A O   1 
ATOM   324  C CB  . SER A 1 49   ? 181.441 194.490 179.182 1.00 203.21 ? 67   SER A CB  1 
ATOM   325  O OG  . SER A 1 49   ? 180.901 193.181 179.129 1.00 198.84 ? 67   SER A OG  1 
ATOM   326  N N   . ASN A 1 50   ? 181.162 197.462 176.969 1.00 211.84 ? 68   ASN A N   1 
ATOM   327  C CA  . ASN A 1 50   ? 181.799 198.744 176.661 1.00 209.98 ? 68   ASN A CA  1 
ATOM   328  C C   . ASN A 1 50   ? 183.306 198.590 176.464 1.00 207.21 ? 68   ASN A C   1 
ATOM   329  O O   . ASN A 1 50   ? 184.090 199.460 176.848 1.00 205.09 ? 68   ASN A O   1 
ATOM   330  C CB  . ASN A 1 50   ? 181.501 199.780 177.747 1.00 208.15 ? 68   ASN A CB  1 
ATOM   331  C CG  . ASN A 1 50   ? 180.027 199.857 178.091 1.00 202.41 ? 68   ASN A CG  1 
ATOM   332  O OD1 . ASN A 1 50   ? 179.213 199.106 177.555 1.00 204.31 ? 68   ASN A OD1 1 
ATOM   333  N ND2 . ASN A 1 50   ? 179.676 200.768 178.992 1.00 192.49 ? 68   ASN A ND2 1 
ATOM   334  N N   . LEU A 1 51   ? 183.711 197.476 175.854 1.00 205.81 ? 69   LEU A N   1 
ATOM   335  C CA  . LEU A 1 51   ? 185.106 197.181 175.523 1.00 202.10 ? 69   LEU A CA  1 
ATOM   336  C C   . LEU A 1 51   ? 185.178 196.932 174.019 1.00 198.26 ? 69   LEU A C   1 
ATOM   337  O O   . LEU A 1 51   ? 185.073 195.792 173.561 1.00 196.12 ? 69   LEU A O   1 
ATOM   338  C CB  . LEU A 1 51   ? 185.628 195.977 176.320 1.00 200.80 ? 69   LEU A CB  1 
ATOM   339  C CG  . LEU A 1 51   ? 185.415 195.993 177.835 1.00 200.14 ? 69   LEU A CG  1 
ATOM   340  C CD1 . LEU A 1 51   ? 185.935 194.706 178.452 1.00 196.81 ? 69   LEU A CD1 1 
ATOM   341  C CD2 . LEU A 1 51   ? 186.096 197.197 178.469 1.00 197.75 ? 69   LEU A CD2 1 
ATOM   342  N N   . THR A 1 52   ? 185.370 198.005 173.250 1.00 200.24 ? 70   THR A N   1 
ATOM   343  C CA  . THR A 1 52   ? 185.424 197.917 171.790 1.00 199.38 ? 70   THR A CA  1 
ATOM   344  C C   . THR A 1 52   ? 186.804 197.402 171.389 1.00 196.91 ? 70   THR A C   1 
ATOM   345  O O   . THR A 1 52   ? 187.713 198.156 171.033 1.00 195.20 ? 70   THR A O   1 
ATOM   346  C CB  . THR A 1 52   ? 185.121 199.267 171.151 1.00 199.08 ? 70   THR A CB  1 
ATOM   347  O OG1 . THR A 1 52   ? 186.233 200.153 171.338 1.00 202.40 ? 70   THR A OG1 1 
ATOM   348  C CG2 . THR A 1 52   ? 183.868 199.886 171.759 1.00 195.89 ? 70   THR A CG2 1 
ATOM   349  N N   . VAL A 1 53   ? 186.952 196.082 171.447 1.00 194.91 ? 71   VAL A N   1 
ATOM   350  C CA  . VAL A 1 53   ? 188.214 195.428 171.114 1.00 189.90 ? 71   VAL A CA  1 
ATOM   351  C C   . VAL A 1 53   ? 188.261 195.241 169.602 1.00 185.58 ? 71   VAL A C   1 
ATOM   352  O O   . VAL A 1 53   ? 187.513 194.437 169.043 1.00 183.29 ? 71   VAL A O   1 
ATOM   353  C CB  . VAL A 1 53   ? 188.363 194.087 171.843 1.00 183.78 ? 71   VAL A CB  1 
ATOM   354  C CG1 . VAL A 1 53   ? 189.790 193.556 171.705 1.00 177.79 ? 71   VAL A CG1 1 
ATOM   355  C CG2 . VAL A 1 53   ? 187.973 194.231 173.310 1.00 186.36 ? 71   VAL A CG2 1 
ATOM   356  N N   . SER A 1 54   ? 189.147 195.981 168.939 1.00 183.38 ? 72   SER A N   1 
ATOM   357  C CA  . SER A 1 54   ? 189.354 195.827 167.505 1.00 178.00 ? 72   SER A CA  1 
ATOM   358  C C   . SER A 1 54   ? 190.259 194.625 167.263 1.00 175.58 ? 72   SER A C   1 
ATOM   359  O O   . SER A 1 54   ? 191.440 194.648 167.627 1.00 178.20 ? 72   SER A O   1 
ATOM   360  C CB  . SER A 1 54   ? 189.967 197.095 166.917 1.00 177.35 ? 72   SER A CB  1 
ATOM   361  O OG  . SER A 1 54   ? 190.361 196.892 165.572 1.00 176.59 ? 72   SER A OG  1 
ATOM   362  N N   . VAL A 1 55   ? 189.709 193.580 166.644 1.00 169.07 ? 73   VAL A N   1 
ATOM   363  C CA  . VAL A 1 55   ? 190.398 192.299 166.530 1.00 162.08 ? 73   VAL A CA  1 
ATOM   364  C C   . VAL A 1 55   ? 191.160 192.228 165.213 1.00 158.47 ? 73   VAL A C   1 
ATOM   365  O O   . VAL A 1 55   ? 192.391 192.110 165.206 1.00 158.33 ? 73   VAL A O   1 
ATOM   366  C CB  . VAL A 1 55   ? 189.405 191.127 166.652 1.00 157.43 ? 73   VAL A CB  1 
ATOM   367  C CG1 . VAL A 1 55   ? 190.153 189.799 166.787 1.00 155.53 ? 73   VAL A CG1 1 
ATOM   368  C CG2 . VAL A 1 55   ? 188.466 191.346 167.834 1.00 166.04 ? 73   VAL A CG2 1 
ATOM   369  N N   . LEU A 1 56   ? 190.437 192.310 164.098 1.00 158.62 ? 74   LEU A N   1 
ATOM   370  C CA  . LEU A 1 56   ? 190.982 192.065 162.769 1.00 158.41 ? 74   LEU A CA  1 
ATOM   371  C C   . LEU A 1 56   ? 190.902 193.334 161.934 1.00 161.12 ? 74   LEU A C   1 
ATOM   372  O O   . LEU A 1 56   ? 189.940 194.101 162.043 1.00 163.31 ? 74   LEU A O   1 
ATOM   373  C CB  . LEU A 1 56   ? 190.227 190.930 162.072 1.00 151.60 ? 74   LEU A CB  1 
ATOM   374  C CG  . LEU A 1 56   ? 190.145 189.613 162.852 1.00 148.47 ? 74   LEU A CG  1 
ATOM   375  C CD1 . LEU A 1 56   ? 189.255 188.612 162.137 1.00 143.65 ? 74   LEU A CD1 1 
ATOM   376  C CD2 . LEU A 1 56   ? 191.530 189.025 163.075 1.00 146.97 ? 74   LEU A CD2 1 
ATOM   377  N N   . GLU A 1 57   ? 191.922 193.545 161.104 1.00 156.56 ? 75   GLU A N   1 
ATOM   378  C CA  . GLU A 1 57   ? 192.042 194.735 160.277 1.00 156.92 ? 75   GLU A CA  1 
ATOM   379  C C   . GLU A 1 57   ? 192.503 194.350 158.880 1.00 153.06 ? 75   GLU A C   1 
ATOM   380  O O   . GLU A 1 57   ? 193.229 193.370 158.694 1.00 151.94 ? 75   GLU A O   1 
ATOM   381  C CB  . GLU A 1 57   ? 193.036 195.738 160.881 1.00 163.78 ? 75   GLU A CB  1 
ATOM   382  C CG  . GLU A 1 57   ? 192.387 196.876 161.651 1.00 170.64 ? 75   GLU A CG  1 
ATOM   383  C CD  . GLU A 1 57   ? 191.734 196.420 162.941 1.00 175.58 ? 75   GLU A CD  1 
ATOM   384  O OE1 . GLU A 1 57   ? 192.259 195.486 163.584 1.00 175.58 ? 75   GLU A OE1 1 
ATOM   385  O OE2 . GLU A 1 57   ? 190.693 196.998 163.316 1.00 178.74 ? 75   GLU A OE2 1 
ATOM   386  N N   . ALA A 1 58   ? 192.068 195.134 157.898 1.00 152.50 ? 76   ALA A N   1 
ATOM   387  C CA  . ALA A 1 58   ? 192.557 194.997 156.535 1.00 146.52 ? 76   ALA A CA  1 
ATOM   388  C C   . ALA A 1 58   ? 192.414 196.338 155.836 1.00 152.17 ? 76   ALA A C   1 
ATOM   389  O O   . ALA A 1 58   ? 191.589 197.171 156.217 1.00 157.12 ? 76   ALA A O   1 
ATOM   390  C CB  . ALA A 1 58   ? 191.806 193.904 155.767 1.00 143.55 ? 76   ALA A CB  1 
ATOM   391  N N   . GLU A 1 59   ? 193.226 196.537 154.801 1.00 154.94 ? 77   GLU A N   1 
ATOM   392  C CA  . GLU A 1 59   ? 193.228 197.793 154.066 1.00 160.98 ? 77   GLU A CA  1 
ATOM   393  C C   . GLU A 1 59   ? 193.641 197.533 152.627 1.00 164.09 ? 77   GLU A C   1 
ATOM   394  O O   . GLU A 1 59   ? 194.497 196.684 152.364 1.00 164.55 ? 77   GLU A O   1 
ATOM   395  C CB  . GLU A 1 59   ? 194.173 198.812 154.712 1.00 164.04 ? 77   GLU A CB  1 
ATOM   396  C CG  . GLU A 1 59   ? 193.667 200.245 154.664 1.00 166.92 ? 77   GLU A CG  1 
ATOM   397  C CD  . GLU A 1 59   ? 194.467 201.182 155.548 1.00 174.05 ? 77   GLU A CD  1 
ATOM   398  O OE1 . GLU A 1 59   ? 195.467 200.733 156.147 1.00 175.32 ? 77   GLU A OE1 1 
ATOM   399  O OE2 . GLU A 1 59   ? 194.095 202.370 155.645 1.00 175.85 ? 77   GLU A OE2 1 
ATOM   400  N N   . GLY A 1 60   ? 193.029 198.263 151.705 1.00 165.81 ? 78   GLY A N   1 
ATOM   401  C CA  . GLY A 1 60   ? 193.345 198.111 150.294 1.00 168.75 ? 78   GLY A CA  1 
ATOM   402  C C   . GLY A 1 60   ? 193.032 199.371 149.523 1.00 174.82 ? 78   GLY A C   1 
ATOM   403  O O   . GLY A 1 60   ? 192.052 200.066 149.804 1.00 177.04 ? 78   GLY A O   1 
ATOM   404  N N   . VAL A 1 61   ? 193.861 199.650 148.519 1.00 176.76 ? 79   VAL A N   1 
ATOM   405  C CA  . VAL A 1 61   ? 193.741 200.840 147.683 1.00 181.99 ? 79   VAL A CA  1 
ATOM   406  C C   . VAL A 1 61   ? 193.160 200.415 146.342 1.00 182.46 ? 79   VAL A C   1 
ATOM   407  O O   . VAL A 1 61   ? 193.594 199.413 145.761 1.00 180.64 ? 79   VAL A O   1 
ATOM   408  C CB  . VAL A 1 61   ? 195.100 201.541 147.502 1.00 181.52 ? 79   VAL A CB  1 
ATOM   409  C CG1 . VAL A 1 61   ? 194.921 202.890 146.808 1.00 185.27 ? 79   VAL A CG1 1 
ATOM   410  C CG2 . VAL A 1 61   ? 195.794 201.708 148.851 1.00 175.69 ? 79   VAL A CG2 1 
ATOM   411  N N   . PHE A 1 62   ? 192.178 201.176 145.857 1.00 182.33 ? 80   PHE A N   1 
ATOM   412  C CA  . PHE A 1 62   ? 191.442 200.857 144.644 1.00 183.37 ? 80   PHE A CA  1 
ATOM   413  C C   . PHE A 1 62   ? 191.364 202.084 143.747 1.00 190.70 ? 80   PHE A C   1 
ATOM   414  O O   . PHE A 1 62   ? 191.410 203.226 144.218 1.00 193.06 ? 80   PHE A O   1 
ATOM   415  C CB  . PHE A 1 62   ? 190.034 200.353 144.977 1.00 176.56 ? 80   PHE A CB  1 
ATOM   416  C CG  . PHE A 1 62   ? 190.021 199.212 145.951 1.00 172.26 ? 80   PHE A CG  1 
ATOM   417  C CD1 . PHE A 1 62   ? 190.189 197.910 145.513 1.00 170.50 ? 80   PHE A CD1 1 
ATOM   418  C CD2 . PHE A 1 62   ? 189.859 199.441 147.306 1.00 171.61 ? 80   PHE A CD2 1 
ATOM   419  C CE1 . PHE A 1 62   ? 190.183 196.857 146.406 1.00 166.54 ? 80   PHE A CE1 1 
ATOM   420  C CE2 . PHE A 1 62   ? 189.854 198.392 148.204 1.00 170.99 ? 80   PHE A CE2 1 
ATOM   421  C CZ  . PHE A 1 62   ? 190.017 197.099 147.753 1.00 165.72 ? 80   PHE A CZ  1 
ATOM   422  N N   . GLU A 1 63   ? 191.243 201.829 142.445 1.00 194.65 ? 81   GLU A N   1 
ATOM   423  C CA  . GLU A 1 63   ? 191.278 202.854 141.415 1.00 196.10 ? 81   GLU A CA  1 
ATOM   424  C C   . GLU A 1 63   ? 189.873 203.121 140.879 1.00 190.55 ? 81   GLU A C   1 
ATOM   425  O O   . GLU A 1 63   ? 188.904 202.438 141.218 1.00 186.19 ? 81   GLU A O   1 
ATOM   426  C CB  . GLU A 1 63   ? 192.217 202.432 140.283 1.00 197.25 ? 81   GLU A CB  1 
ATOM   427  C CG  . GLU A 1 63   ? 193.662 202.246 140.716 1.00 206.57 ? 81   GLU A CG  1 
ATOM   428  C CD  . GLU A 1 63   ? 193.974 200.822 141.136 1.00 209.13 ? 81   GLU A CD  1 
ATOM   429  O OE1 . GLU A 1 63   ? 193.045 200.105 141.564 1.00 203.66 ? 81   GLU A OE1 1 
ATOM   430  O OE2 . GLU A 1 63   ? 195.152 200.419 141.040 1.00 213.14 ? 81   GLU A OE2 1 
ATOM   431  N N   . LYS A 1 64   ? 189.770 204.137 140.027 1.00 193.36 ? 82   LYS A N   1 
ATOM   432  C CA  . LYS A 1 64   ? 188.497 204.481 139.412 1.00 194.09 ? 82   LYS A CA  1 
ATOM   433  C C   . LYS A 1 64   ? 188.081 203.404 138.418 1.00 190.17 ? 82   LYS A C   1 
ATOM   434  O O   . LYS A 1 64   ? 188.912 202.877 137.672 1.00 187.88 ? 82   LYS A O   1 
ATOM   435  C CB  . LYS A 1 64   ? 188.600 205.837 138.715 1.00 199.70 ? 82   LYS A CB  1 
ATOM   436  C CG  . LYS A 1 64   ? 187.338 206.269 137.984 1.00 201.11 ? 82   LYS A CG  1 
ATOM   437  C CD  . LYS A 1 64   ? 187.353 207.763 137.702 1.00 205.59 ? 82   LYS A CD  1 
ATOM   438  C CE  . LYS A 1 64   ? 186.479 208.121 136.512 1.00 205.92 ? 82   LYS A CE  1 
ATOM   439  N NZ  . LYS A 1 64   ? 186.323 209.594 136.361 1.00 211.12 ? 82   LYS A NZ  1 
ATOM   440  N N   . GLY A 1 65   ? 186.792 203.076 138.412 1.00 187.95 ? 83   GLY A N   1 
ATOM   441  C CA  . GLY A 1 65   ? 186.283 202.073 137.500 1.00 182.06 ? 83   GLY A CA  1 
ATOM   442  C C   . GLY A 1 65   ? 186.680 200.654 137.830 1.00 176.95 ? 83   GLY A C   1 
ATOM   443  O O   . GLY A 1 65   ? 186.535 199.773 136.977 1.00 170.37 ? 83   GLY A O   1 
ATOM   444  N N   . SER A 1 66   ? 187.169 200.403 139.043 1.00 179.82 ? 84   SER A N   1 
ATOM   445  C CA  . SER A 1 66   ? 187.646 199.092 139.461 1.00 175.80 ? 84   SER A CA  1 
ATOM   446  C C   . SER A 1 66   ? 186.629 198.460 140.399 1.00 170.45 ? 84   SER A C   1 
ATOM   447  O O   . SER A 1 66   ? 186.214 199.084 141.381 1.00 172.45 ? 84   SER A O   1 
ATOM   448  C CB  . SER A 1 66   ? 189.004 199.201 140.157 1.00 177.12 ? 84   SER A CB  1 
ATOM   449  O OG  . SER A 1 66   ? 188.907 199.961 141.348 1.00 181.76 ? 84   SER A OG  1 
ATOM   450  N N   . PHE A 1 67   ? 186.233 197.227 140.085 1.00 164.15 ? 85   PHE A N   1 
ATOM   451  C CA  . PHE A 1 67   ? 185.320 196.427 140.897 1.00 158.72 ? 85   PHE A CA  1 
ATOM   452  C C   . PHE A 1 67   ? 186.131 195.278 141.481 1.00 154.35 ? 85   PHE A C   1 
ATOM   453  O O   . PHE A 1 67   ? 186.474 194.331 140.764 1.00 147.06 ? 85   PHE A O   1 
ATOM   454  C CB  . PHE A 1 67   ? 184.151 195.931 140.042 1.00 156.36 ? 85   PHE A CB  1 
ATOM   455  C CG  . PHE A 1 67   ? 183.092 195.144 140.794 1.00 147.66 ? 85   PHE A CG  1 
ATOM   456  C CD1 . PHE A 1 67   ? 182.867 195.310 142.153 1.00 145.01 ? 85   PHE A CD1 1 
ATOM   457  C CD2 . PHE A 1 67   ? 182.298 194.243 140.106 1.00 141.05 ? 85   PHE A CD2 1 
ATOM   458  C CE1 . PHE A 1 67   ? 181.891 194.587 142.804 1.00 140.88 ? 85   PHE A CE1 1 
ATOM   459  C CE2 . PHE A 1 67   ? 181.320 193.521 140.753 1.00 134.66 ? 85   PHE A CE2 1 
ATOM   460  C CZ  . PHE A 1 67   ? 181.116 193.694 142.103 1.00 133.76 ? 85   PHE A CZ  1 
ATOM   461  N N   . LYS A 1 68   ? 186.434 195.362 142.778 1.00 152.74 ? 86   LYS A N   1 
ATOM   462  C CA  . LYS A 1 68   ? 187.420 194.489 143.408 1.00 145.05 ? 86   LYS A CA  1 
ATOM   463  C C   . LYS A 1 68   ? 186.904 194.054 144.775 1.00 140.60 ? 86   LYS A C   1 
ATOM   464  O O   . LYS A 1 68   ? 185.802 194.425 145.191 1.00 139.93 ? 86   LYS A O   1 
ATOM   465  C CB  . LYS A 1 68   ? 188.777 195.202 143.498 1.00 149.95 ? 86   LYS A CB  1 
ATOM   466  C CG  . LYS A 1 68   ? 189.690 194.923 142.318 1.00 154.16 ? 86   LYS A CG  1 
ATOM   467  C CD  . LYS A 1 68   ? 191.020 195.643 142.465 1.00 168.19 ? 86   LYS A CD  1 
ATOM   468  C CE  . LYS A 1 68   ? 191.874 195.491 141.218 1.00 177.66 ? 86   LYS A CE  1 
ATOM   469  N NZ  . LYS A 1 68   ? 193.133 196.282 141.305 1.00 184.96 ? 86   LYS A NZ  1 
ATOM   470  N N   . THR A 1 69   ? 187.705 193.235 145.464 1.00 137.64 ? 87   THR A N   1 
ATOM   471  C CA  . THR A 1 69   ? 187.388 192.723 146.791 1.00 137.03 ? 87   THR A CA  1 
ATOM   472  C C   . THR A 1 69   ? 188.487 193.093 147.773 1.00 135.62 ? 87   THR A C   1 
ATOM   473  O O   . THR A 1 69   ? 189.667 193.142 147.414 1.00 136.78 ? 87   THR A O   1 
ATOM   474  C CB  . THR A 1 69   ? 187.229 191.199 146.794 1.00 136.16 ? 87   THR A CB  1 
ATOM   475  O OG1 . THR A 1 69   ? 188.417 190.592 146.272 1.00 138.51 ? 87   THR A OG1 1 
ATOM   476  C CG2 . THR A 1 69   ? 186.048 190.783 145.958 1.00 136.58 ? 87   THR A CG2 1 
ATOM   477  N N   . LEU A 1 70   ? 188.081 193.357 149.012 1.00 133.34 ? 88   LEU A N   1 
ATOM   478  C CA  . LEU A 1 70   ? 188.978 193.465 150.153 1.00 129.97 ? 88   LEU A CA  1 
ATOM   479  C C   . LEU A 1 70   ? 188.635 192.335 151.113 1.00 130.37 ? 88   LEU A C   1 
ATOM   480  O O   . LEU A 1 70   ? 187.483 192.215 151.546 1.00 131.81 ? 88   LEU A O   1 
ATOM   481  C CB  . LEU A 1 70   ? 188.840 194.826 150.836 1.00 136.45 ? 88   LEU A CB  1 
ATOM   482  C CG  . LEU A 1 70   ? 189.760 195.115 152.025 1.00 146.79 ? 88   LEU A CG  1 
ATOM   483  C CD1 . LEU A 1 70   ? 191.221 195.136 151.605 1.00 150.17 ? 88   LEU A CD1 1 
ATOM   484  C CD2 . LEU A 1 70   ? 189.373 196.432 152.679 1.00 155.71 ? 88   LEU A CD2 1 
ATOM   485  N N   . THR A 1 71   ? 189.630 191.514 151.440 1.00 130.62 ? 89   THR A N   1 
ATOM   486  C CA  . THR A 1 71   ? 189.447 190.317 152.252 1.00 133.85 ? 89   THR A CA  1 
ATOM   487  C C   . THR A 1 71   ? 190.111 190.525 153.604 1.00 132.97 ? 89   THR A C   1 
ATOM   488  O O   . THR A 1 71   ? 191.316 190.790 153.673 1.00 137.30 ? 89   THR A O   1 
ATOM   489  C CB  . THR A 1 71   ? 190.035 189.092 151.552 1.00 138.37 ? 89   THR A CB  1 
ATOM   490  O OG1 . THR A 1 71   ? 189.520 189.008 150.218 1.00 146.56 ? 89   THR A OG1 1 
ATOM   491  C CG2 . THR A 1 71   ? 189.690 187.816 152.310 1.00 138.22 ? 89   THR A CG2 1 
ATOM   492  N N   . LEU A 1 72   ? 189.327 190.403 154.669 1.00 130.01 ? 90   LEU A N   1 
ATOM   493  C CA  . LEU A 1 72   ? 189.883 190.457 156.008 1.00 129.87 ? 90   LEU A CA  1 
ATOM   494  C C   . LEU A 1 72   ? 190.547 189.120 156.343 1.00 134.83 ? 90   LEU A C   1 
ATOM   495  O O   . LEU A 1 72   ? 190.221 188.095 155.739 1.00 137.32 ? 90   LEU A O   1 
ATOM   496  C CB  . LEU A 1 72   ? 188.790 190.757 157.029 1.00 129.82 ? 90   LEU A CB  1 
ATOM   497  C CG  . LEU A 1 72   ? 188.432 192.230 157.232 1.00 140.21 ? 90   LEU A CG  1 
ATOM   498  C CD1 . LEU A 1 72   ? 186.992 192.359 157.695 1.00 143.38 ? 90   LEU A CD1 1 
ATOM   499  C CD2 . LEU A 1 72   ? 189.371 192.891 158.227 1.00 152.81 ? 90   LEU A CD2 1 
ATOM   500  N N   . PRO A 1 73   ? 191.481 189.094 157.295 1.00 137.28 ? 91   PRO A N   1 
ATOM   501  C CA  . PRO A 1 73   ? 192.001 187.801 157.752 1.00 138.96 ? 91   PRO A CA  1 
ATOM   502  C C   . PRO A 1 73   ? 190.912 186.991 158.434 1.00 143.42 ? 91   PRO A C   1 
ATOM   503  O O   . PRO A 1 73   ? 189.957 187.534 158.994 1.00 143.44 ? 91   PRO A O   1 
ATOM   504  C CB  . PRO A 1 73   ? 193.116 188.182 158.733 1.00 136.33 ? 91   PRO A CB  1 
ATOM   505  C CG  . PRO A 1 73   ? 192.831 189.576 159.125 1.00 140.18 ? 91   PRO A CG  1 
ATOM   506  C CD  . PRO A 1 73   ? 192.187 190.214 157.943 1.00 138.36 ? 91   PRO A CD  1 
ATOM   507  N N   . SER A 1 74   ? 191.055 185.672 158.365 1.00 147.43 ? 92   SER A N   1 
ATOM   508  C CA  . SER A 1 74   ? 190.039 184.785 158.914 1.00 144.67 ? 92   SER A CA  1 
ATOM   509  C C   . SER A 1 74   ? 189.998 184.884 160.433 1.00 139.78 ? 92   SER A C   1 
ATOM   510  O O   . SER A 1 74   ? 191.034 184.980 161.096 1.00 142.00 ? 92   SER A O   1 
ATOM   511  C CB  . SER A 1 74   ? 190.315 183.343 158.496 1.00 146.63 ? 92   SER A CB  1 
ATOM   512  O OG  . SER A 1 74   ? 191.565 182.900 158.993 1.00 156.66 ? 92   SER A OG  1 
ATOM   513  N N   . LEU A 1 75   ? 188.788 184.867 160.982 1.00 132.17 ? 93   LEU A N   1 
ATOM   514  C CA  . LEU A 1 75   ? 188.633 184.814 162.426 1.00 130.52 ? 93   LEU A CA  1 
ATOM   515  C C   . LEU A 1 75   ? 189.058 183.433 162.931 1.00 138.52 ? 93   LEU A C   1 
ATOM   516  O O   . LEU A 1 75   ? 188.771 182.426 162.277 1.00 141.76 ? 93   LEU A O   1 
ATOM   517  C CB  . LEU A 1 75   ? 187.178 185.089 162.808 1.00 122.24 ? 93   LEU A CB  1 
ATOM   518  C CG  . LEU A 1 75   ? 186.821 185.226 164.291 1.00 126.40 ? 93   LEU A CG  1 
ATOM   519  C CD1 . LEU A 1 75   ? 187.184 186.605 164.810 1.00 137.26 ? 93   LEU A CD1 1 
ATOM   520  C CD2 . LEU A 1 75   ? 185.343 184.950 164.503 1.00 128.75 ? 93   LEU A CD2 1 
ATOM   521  N N   . PRO A 1 76   ? 189.741 183.338 164.077 1.00 138.99 ? 94   PRO A N   1 
ATOM   522  C CA  . PRO A 1 76   ? 190.092 182.008 164.587 1.00 135.58 ? 94   PRO A CA  1 
ATOM   523  C C   . PRO A 1 76   ? 188.862 181.239 165.038 1.00 132.52 ? 94   PRO A C   1 
ATOM   524  O O   . PRO A 1 76   ? 187.852 181.815 165.449 1.00 132.54 ? 94   PRO A O   1 
ATOM   525  C CB  . PRO A 1 76   ? 191.025 182.309 165.765 1.00 135.09 ? 94   PRO A CB  1 
ATOM   526  C CG  . PRO A 1 76   ? 190.647 183.657 166.206 1.00 135.88 ? 94   PRO A CG  1 
ATOM   527  C CD  . PRO A 1 76   ? 190.260 184.396 164.966 1.00 135.29 ? 94   PRO A CD  1 
ATOM   528  N N   . LEU A 1 77   ? 188.962 179.913 164.960 1.00 128.70 ? 95   LEU A N   1 
ATOM   529  C CA  . LEU A 1 77   ? 187.849 179.041 165.311 1.00 127.11 ? 95   LEU A CA  1 
ATOM   530  C C   . LEU A 1 77   ? 187.572 178.993 166.808 1.00 135.00 ? 95   LEU A C   1 
ATOM   531  O O   . LEU A 1 77   ? 186.511 178.500 167.206 1.00 137.05 ? 95   LEU A O   1 
ATOM   532  C CB  . LEU A 1 77   ? 188.119 177.625 164.801 1.00 117.35 ? 95   LEU A CB  1 
ATOM   533  C CG  . LEU A 1 77   ? 188.324 177.510 163.289 1.00 115.54 ? 95   LEU A CG  1 
ATOM   534  C CD1 . LEU A 1 77   ? 189.725 177.018 162.973 1.00 119.89 ? 95   LEU A CD1 1 
ATOM   535  C CD2 . LEU A 1 77   ? 187.286 176.590 162.679 1.00 112.03 ? 95   LEU A CD2 1 
ATOM   536  N N   . ASN A 1 78   ? 188.485 179.488 167.645 1.00 137.27 ? 96   ASN A N   1 
ATOM   537  C CA  . ASN A 1 78   ? 188.269 179.494 169.085 1.00 140.24 ? 96   ASN A CA  1 
ATOM   538  C C   . ASN A 1 78   ? 187.256 180.538 169.539 1.00 143.41 ? 96   ASN A C   1 
ATOM   539  O O   . ASN A 1 78   ? 186.856 180.513 170.707 1.00 147.72 ? 96   ASN A O   1 
ATOM   540  C CB  . ASN A 1 78   ? 189.594 179.739 169.811 1.00 144.86 ? 96   ASN A CB  1 
ATOM   541  C CG  . ASN A 1 78   ? 190.587 178.615 169.608 1.00 153.39 ? 96   ASN A CG  1 
ATOM   542  O OD1 . ASN A 1 78   ? 190.214 177.445 169.549 1.00 160.62 ? 96   ASN A OD1 1 
ATOM   543  N ND2 . ASN A 1 78   ? 191.863 178.965 169.500 1.00 154.59 ? 96   ASN A ND2 1 
ATOM   544  N N   . SER A 1 79   ? 186.833 181.445 168.662 1.00 144.04 ? 97   SER A N   1 
ATOM   545  C CA  . SER A 1 79   ? 185.911 182.493 169.065 1.00 147.00 ? 97   SER A CA  1 
ATOM   546  C C   . SER A 1 79   ? 184.543 181.907 169.403 1.00 146.47 ? 97   SER A C   1 
ATOM   547  O O   . SER A 1 79   ? 184.193 180.797 168.993 1.00 144.87 ? 97   SER A O   1 
ATOM   548  C CB  . SER A 1 79   ? 185.774 183.539 167.959 1.00 146.57 ? 97   SER A CB  1 
ATOM   549  O OG  . SER A 1 79   ? 186.984 184.255 167.788 1.00 146.10 ? 97   SER A OG  1 
ATOM   550  N N   . ALA A 1 80   ? 183.772 182.678 170.172 1.00 148.82 ? 98   ALA A N   1 
ATOM   551  C CA  . ALA A 1 80   ? 182.445 182.279 170.627 1.00 153.49 ? 98   ALA A CA  1 
ATOM   552  C C   . ALA A 1 80   ? 181.420 183.344 170.255 1.00 158.67 ? 98   ALA A C   1 
ATOM   553  O O   . ALA A 1 80   ? 181.731 184.276 169.506 1.00 157.95 ? 98   ALA A O   1 
ATOM   554  C CB  . ALA A 1 80   ? 182.453 182.036 172.138 1.00 149.35 ? 98   ALA A CB  1 
ATOM   555  N N   . ASP A 1 81   ? 180.196 183.209 170.761 1.00 164.38 ? 99   ASP A N   1 
ATOM   556  C CA  . ASP A 1 81   ? 179.119 184.145 170.453 1.00 168.47 ? 99   ASP A CA  1 
ATOM   557  C C   . ASP A 1 81   ? 179.456 185.448 171.169 1.00 173.30 ? 99   ASP A C   1 
ATOM   558  O O   . ASP A 1 81   ? 179.261 185.576 172.379 1.00 181.84 ? 99   ASP A O   1 
ATOM   559  C CB  . ASP A 1 81   ? 177.781 183.547 170.895 1.00 183.19 ? 99   ASP A CB  1 
ATOM   560  C CG  . ASP A 1 81   ? 176.572 184.505 170.764 1.00 190.80 ? 99   ASP A CG  1 
ATOM   561  O OD1 . ASP A 1 81   ? 176.686 185.750 170.729 1.00 188.99 ? 99   ASP A OD1 1 
ATOM   562  O OD2 . ASP A 1 81   ? 175.447 183.967 170.676 1.00 196.12 ? 99   ASP A OD2 1 
ATOM   563  N N   . GLU A 1 82   ? 179.975 186.414 170.417 1.00 163.86 ? 100  GLU A N   1 
ATOM   564  C CA  . GLU A 1 82   ? 180.248 187.757 170.903 1.00 163.96 ? 100  GLU A CA  1 
ATOM   565  C C   . GLU A 1 82   ? 179.651 188.770 169.937 1.00 164.65 ? 100  GLU A C   1 
ATOM   566  O O   . GLU A 1 82   ? 179.500 188.503 168.743 1.00 164.89 ? 100  GLU A O   1 
ATOM   567  C CB  . GLU A 1 82   ? 181.755 188.005 171.061 1.00 162.19 ? 100  GLU A CB  1 
ATOM   568  C CG  . GLU A 1 82   ? 182.405 187.170 172.156 1.00 165.87 ? 100  GLU A CG  1 
ATOM   569  C CD  . GLU A 1 82   ? 183.669 186.466 171.696 1.00 167.88 ? 100  GLU A CD  1 
ATOM   570  O OE1 . GLU A 1 82   ? 183.640 185.811 170.633 1.00 165.80 ? 100  GLU A OE1 1 
ATOM   571  O OE2 . GLU A 1 82   ? 184.691 186.559 172.407 1.00 171.90 ? 100  GLU A OE2 1 
ATOM   572  N N   . ILE A 1 83   ? 179.299 189.936 170.469 1.00 167.32 ? 101  ILE A N   1 
ATOM   573  C CA  . ILE A 1 83   ? 178.716 191.003 169.663 1.00 170.52 ? 101  ILE A CA  1 
ATOM   574  C C   . ILE A 1 83   ? 179.812 191.539 168.749 1.00 167.51 ? 101  ILE A C   1 
ATOM   575  O O   . ILE A 1 83   ? 180.743 192.204 169.209 1.00 167.67 ? 101  ILE A O   1 
ATOM   576  C CB  . ILE A 1 83   ? 178.128 192.116 170.538 1.00 175.00 ? 101  ILE A CB  1 
ATOM   577  C CG1 . ILE A 1 83   ? 177.026 191.577 171.468 1.00 174.37 ? 101  ILE A CG1 1 
ATOM   578  C CG2 . ILE A 1 83   ? 177.620 193.260 169.668 1.00 175.58 ? 101  ILE A CG2 1 
ATOM   579  C CD1 . ILE A 1 83   ? 175.839 190.913 170.772 1.00 169.19 ? 101  ILE A CD1 1 
ATOM   580  N N   . TYR A 1 84   ? 179.694 191.257 167.453 1.00 161.96 ? 102  TYR A N   1 
ATOM   581  C CA  . TYR A 1 84   ? 180.704 191.599 166.460 1.00 155.00 ? 102  TYR A CA  1 
ATOM   582  C C   . TYR A 1 84   ? 180.189 192.716 165.565 1.00 151.42 ? 102  TYR A C   1 
ATOM   583  O O   . TYR A 1 84   ? 179.046 192.664 165.092 1.00 151.34 ? 102  TYR A O   1 
ATOM   584  C CB  . TYR A 1 84   ? 181.073 190.379 165.616 1.00 146.84 ? 102  TYR A CB  1 
ATOM   585  C CG  . TYR A 1 84   ? 182.135 189.505 166.241 1.00 146.38 ? 102  TYR A CG  1 
ATOM   586  C CD1 . TYR A 1 84   ? 183.457 189.922 166.304 1.00 151.19 ? 102  TYR A CD1 1 
ATOM   587  C CD2 . TYR A 1 84   ? 181.815 188.263 166.768 1.00 148.68 ? 102  TYR A CD2 1 
ATOM   588  C CE1 . TYR A 1 84   ? 184.428 189.129 166.873 1.00 154.07 ? 102  TYR A CE1 1 
ATOM   589  C CE2 . TYR A 1 84   ? 182.780 187.462 167.340 1.00 152.33 ? 102  TYR A CE2 1 
ATOM   590  C CZ  . TYR A 1 84   ? 184.085 187.900 167.390 1.00 153.80 ? 102  TYR A CZ  1 
ATOM   591  O OH  . TYR A 1 84   ? 185.051 187.104 167.960 1.00 157.17 ? 102  TYR A OH  1 
ATOM   592  N N   . GLU A 1 85   ? 181.041 193.713 165.331 1.00 151.11 ? 103  GLU A N   1 
ATOM   593  C CA  . GLU A 1 85   ? 180.719 194.866 164.502 1.00 150.56 ? 103  GLU A CA  1 
ATOM   594  C C   . GLU A 1 85   ? 181.756 195.000 163.398 1.00 152.49 ? 103  GLU A C   1 
ATOM   595  O O   . GLU A 1 85   ? 182.960 194.950 163.663 1.00 156.44 ? 103  GLU A O   1 
ATOM   596  C CB  . GLU A 1 85   ? 180.675 196.150 165.335 1.00 156.77 ? 103  GLU A CB  1 
ATOM   597  C CG  . GLU A 1 85   ? 179.442 196.273 166.234 1.00 162.74 ? 103  GLU A CG  1 
ATOM   598  C CD  . GLU A 1 85   ? 178.942 197.704 166.395 1.00 171.29 ? 103  GLU A CD  1 
ATOM   599  O OE1 . GLU A 1 85   ? 179.694 198.656 166.095 1.00 177.52 ? 103  GLU A OE1 1 
ATOM   600  O OE2 . GLU A 1 85   ? 177.783 197.875 166.827 1.00 171.16 ? 103  GLU A OE2 1 
ATOM   601  N N   . LEU A 1 86   ? 181.285 195.172 162.166 1.00 149.66 ? 104  LEU A N   1 
ATOM   602  C CA  . LEU A 1 86   ? 182.143 195.426 161.016 1.00 149.13 ? 104  LEU A CA  1 
ATOM   603  C C   . LEU A 1 86   ? 182.063 196.906 160.678 1.00 153.12 ? 104  LEU A C   1 
ATOM   604  O O   . LEU A 1 86   ? 180.965 197.437 160.481 1.00 155.47 ? 104  LEU A O   1 
ATOM   605  C CB  . LEU A 1 86   ? 181.723 194.571 159.820 1.00 142.26 ? 104  LEU A CB  1 
ATOM   606  C CG  . LEU A 1 86   ? 182.352 194.869 158.454 1.00 144.53 ? 104  LEU A CG  1 
ATOM   607  C CD1 . LEU A 1 86   ? 183.863 194.738 158.512 1.00 155.01 ? 104  LEU A CD1 1 
ATOM   608  C CD2 . LEU A 1 86   ? 181.779 193.932 157.407 1.00 144.96 ? 104  LEU A CD2 1 
ATOM   609  N N   . ARG A 1 87   ? 183.222 197.560 160.616 1.00 154.96 ? 105  ARG A N   1 
ATOM   610  C CA  . ARG A 1 87   ? 183.343 198.963 160.248 1.00 160.57 ? 105  ARG A CA  1 
ATOM   611  C C   . ARG A 1 87   ? 184.079 199.057 158.920 1.00 162.24 ? 105  ARG A C   1 
ATOM   612  O O   . ARG A 1 87   ? 185.152 198.465 158.758 1.00 161.84 ? 105  ARG A O   1 
ATOM   613  C CB  . ARG A 1 87   ? 184.088 199.752 161.331 1.00 165.83 ? 105  ARG A CB  1 
ATOM   614  C CG  . ARG A 1 87   ? 184.202 201.260 161.074 1.00 169.71 ? 105  ARG A CG  1 
ATOM   615  C CD  . ARG A 1 87   ? 185.117 201.939 162.084 1.00 171.48 ? 105  ARG A CD  1 
ATOM   616  N NE  . ARG A 1 87   ? 184.716 201.685 163.464 1.00 172.50 ? 105  ARG A NE  1 
ATOM   617  C CZ  . ARG A 1 87   ? 183.742 202.319 164.107 1.00 171.14 ? 105  ARG A CZ  1 
ATOM   618  N NH1 . ARG A 1 87   ? 183.013 203.259 163.522 1.00 167.81 ? 105  ARG A NH1 1 
ATOM   619  N NH2 . ARG A 1 87   ? 183.490 202.002 165.373 1.00 168.19 ? 105  ARG A NH2 1 
ATOM   620  N N   . VAL A 1 88   ? 183.499 199.797 157.979 1.00 165.35 ? 106  VAL A N   1 
ATOM   621  C CA  . VAL A 1 88   ? 184.094 200.061 156.675 1.00 164.15 ? 106  VAL A CA  1 
ATOM   622  C C   . VAL A 1 88   ? 184.304 201.562 156.562 1.00 168.99 ? 106  VAL A C   1 
ATOM   623  O O   . VAL A 1 88   ? 183.369 202.344 156.792 1.00 172.21 ? 106  VAL A O   1 
ATOM   624  C CB  . VAL A 1 88   ? 183.207 199.539 155.531 1.00 165.42 ? 106  VAL A CB  1 
ATOM   625  C CG1 . VAL A 1 88   ? 183.878 199.780 154.179 1.00 169.26 ? 106  VAL A CG1 1 
ATOM   626  C CG2 . VAL A 1 88   ? 182.897 198.057 155.732 1.00 164.17 ? 106  VAL A CG2 1 
ATOM   627  N N   . THR A 1 89   ? 185.526 201.962 156.208 1.00 170.94 ? 107  THR A N   1 
ATOM   628  C CA  . THR A 1 89   ? 185.899 203.369 156.092 1.00 176.27 ? 107  THR A CA  1 
ATOM   629  C C   . THR A 1 89   ? 186.677 203.563 154.799 1.00 176.93 ? 107  THR A C   1 
ATOM   630  O O   . THR A 1 89   ? 187.807 203.083 154.674 1.00 173.31 ? 107  THR A O   1 
ATOM   631  C CB  . THR A 1 89   ? 186.730 203.817 157.295 1.00 178.46 ? 107  THR A CB  1 
ATOM   632  O OG1 . THR A 1 89   ? 185.962 203.659 158.495 1.00 176.22 ? 107  THR A OG1 1 
ATOM   633  C CG2 . THR A 1 89   ? 187.146 205.274 157.149 1.00 180.68 ? 107  THR A CG2 1 
ATOM   634  N N   . GLY A 1 90   ? 186.068 204.258 153.844 1.00 182.27 ? 108  GLY A N   1 
ATOM   635  C CA  . GLY A 1 90   ? 186.733 204.639 152.610 1.00 188.32 ? 108  GLY A CA  1 
ATOM   636  C C   . GLY A 1 90   ? 187.206 206.079 152.699 1.00 195.92 ? 108  GLY A C   1 
ATOM   637  O O   . GLY A 1 90   ? 186.447 206.970 153.086 1.00 195.48 ? 108  GLY A O   1 
ATOM   638  N N   . ARG A 1 91   ? 188.466 206.289 152.320 1.00 200.12 ? 109  ARG A N   1 
ATOM   639  C CA  . ARG A 1 91   ? 189.140 207.570 152.449 1.00 207.56 ? 109  ARG A CA  1 
ATOM   640  C C   . ARG A 1 91   ? 189.824 207.912 151.136 1.00 209.09 ? 109  ARG A C   1 
ATOM   641  O O   . ARG A 1 91   ? 190.207 207.031 150.361 1.00 202.45 ? 109  ARG A O   1 
ATOM   642  C CB  . ARG A 1 91   ? 190.189 207.544 153.569 1.00 209.27 ? 109  ARG A CB  1 
ATOM   643  C CG  . ARG A 1 91   ? 189.650 207.790 154.970 1.00 209.28 ? 109  ARG A CG  1 
ATOM   644  C CD  . ARG A 1 91   ? 190.690 208.441 155.881 1.00 217.95 ? 109  ARG A CD  1 
ATOM   645  N NE  . ARG A 1 91   ? 190.981 209.827 155.511 1.00 224.49 ? 109  ARG A NE  1 
ATOM   646  C CZ  . ARG A 1 91   ? 192.050 210.260 154.846 1.00 227.80 ? 109  ARG A CZ  1 
ATOM   647  N NH1 . ARG A 1 91   ? 192.990 209.435 154.406 1.00 229.29 ? 109  ARG A NH1 1 
ATOM   648  N NH2 . ARG A 1 91   ? 192.176 211.562 154.607 1.00 230.09 ? 109  ARG A NH2 1 
ATOM   649  N N   . THR A 1 92   ? 189.970 209.210 150.898 1.00 219.50 ? 110  THR A N   1 
ATOM   650  C CA  . THR A 1 92   ? 190.775 209.718 149.799 1.00 227.54 ? 110  THR A CA  1 
ATOM   651  C C   . THR A 1 92   ? 192.209 209.906 150.290 1.00 234.01 ? 110  THR A C   1 
ATOM   652  O O   . THR A 1 92   ? 192.538 209.615 151.444 1.00 231.00 ? 110  THR A O   1 
ATOM   653  C CB  . THR A 1 92   ? 190.189 211.021 149.260 1.00 230.28 ? 110  THR A CB  1 
ATOM   654  O OG1 . THR A 1 92   ? 190.518 212.100 150.145 1.00 236.41 ? 110  THR A OG1 1 
ATOM   655  C CG2 . THR A 1 92   ? 188.675 210.919 149.125 1.00 222.94 ? 110  THR A CG2 1 
ATOM   656  N N   . GLN A 1 93   ? 193.084 210.401 149.416 1.00 241.52 ? 111  GLN A N   1 
ATOM   657  C CA  . GLN A 1 93   ? 194.458 210.680 149.814 1.00 247.11 ? 111  GLN A CA  1 
ATOM   658  C C   . GLN A 1 93   ? 194.563 211.851 150.785 1.00 248.38 ? 111  GLN A C   1 
ATOM   659  O O   . GLN A 1 93   ? 195.576 211.961 151.485 1.00 249.39 ? 111  GLN A O   1 
ATOM   660  C CB  . GLN A 1 93   ? 195.323 210.928 148.565 1.00 249.40 ? 111  GLN A CB  1 
ATOM   661  C CG  . GLN A 1 93   ? 195.243 212.323 147.907 1.00 252.01 ? 111  GLN A CG  1 
ATOM   662  C CD  . GLN A 1 93   ? 193.893 212.607 147.280 1.00 250.31 ? 111  GLN A CD  1 
ATOM   663  O OE1 . GLN A 1 93   ? 193.036 211.727 147.199 1.00 246.50 ? 111  GLN A OE1 1 
ATOM   664  N NE2 . GLN A 1 93   ? 193.695 213.841 146.832 1.00 251.56 ? 111  GLN A NE2 1 
ATOM   665  N N   . ASP A 1 94   ? 193.548 212.721 150.838 1.00 247.75 ? 112  ASP A N   1 
ATOM   666  C CA  . ASP A 1 94   ? 193.562 213.898 151.701 1.00 244.94 ? 112  ASP A CA  1 
ATOM   667  C C   . ASP A 1 94   ? 192.262 214.137 152.455 1.00 239.72 ? 112  ASP A C   1 
ATOM   668  O O   . ASP A 1 94   ? 192.223 215.059 153.276 1.00 237.27 ? 112  ASP A O   1 
ATOM   669  C CB  . ASP A 1 94   ? 193.884 215.150 150.874 1.00 246.61 ? 112  ASP A CB  1 
ATOM   670  C CG  . ASP A 1 94   ? 193.041 215.248 149.619 1.00 248.29 ? 112  ASP A CG  1 
ATOM   671  O OD1 . ASP A 1 94   ? 192.333 214.270 149.300 1.00 248.76 ? 112  ASP A OD1 1 
ATOM   672  O OD2 . ASP A 1 94   ? 193.086 216.302 148.950 1.00 248.56 ? 112  ASP A OD2 1 
ATOM   673  N N   . GLU A 1 95   ? 191.206 213.361 152.216 1.00 237.07 ? 113  GLU A N   1 
ATOM   674  C CA  . GLU A 1 95   ? 189.923 213.586 152.865 1.00 230.47 ? 113  GLU A CA  1 
ATOM   675  C C   . GLU A 1 95   ? 189.183 212.263 152.984 1.00 225.59 ? 113  GLU A C   1 
ATOM   676  O O   . GLU A 1 95   ? 189.447 211.312 152.245 1.00 225.74 ? 113  GLU A O   1 
ATOM   677  C CB  . GLU A 1 95   ? 189.071 214.596 152.087 1.00 230.56 ? 113  GLU A CB  1 
ATOM   678  C CG  . GLU A 1 95   ? 188.106 215.401 152.962 1.00 229.57 ? 113  GLU A CG  1 
ATOM   679  C CD  . GLU A 1 95   ? 186.805 215.782 152.262 1.00 229.27 ? 113  GLU A CD  1 
ATOM   680  O OE1 . GLU A 1 95   ? 186.682 215.591 151.033 1.00 228.90 ? 113  GLU A OE1 1 
ATOM   681  O OE2 . GLU A 1 95   ? 185.892 216.277 152.956 1.00 226.34 ? 113  GLU A OE2 1 
ATOM   682  N N   . ILE A 1 96   ? 188.249 212.215 153.932 1.00 221.32 ? 114  ILE A N   1 
ATOM   683  C CA  . ILE A 1 96   ? 187.385 211.051 154.070 1.00 213.83 ? 114  ILE A CA  1 
ATOM   684  C C   . ILE A 1 96   ? 186.354 211.040 152.946 1.00 212.46 ? 114  ILE A C   1 
ATOM   685  O O   . ILE A 1 96   ? 185.989 212.080 152.389 1.00 215.79 ? 114  ILE A O   1 
ATOM   686  C CB  . ILE A 1 96   ? 186.706 211.011 155.458 1.00 208.51 ? 114  ILE A CB  1 
ATOM   687  C CG1 . ILE A 1 96   ? 185.832 212.256 155.715 1.00 208.25 ? 114  ILE A CG1 1 
ATOM   688  C CG2 . ILE A 1 96   ? 187.758 210.872 156.554 1.00 208.71 ? 114  ILE A CG2 1 
ATOM   689  C CD1 . ILE A 1 96   ? 185.047 212.196 157.013 1.00 205.51 ? 114  ILE A CD1 1 
ATOM   690  N N   . LEU A 1 97   ? 185.886 209.838 152.610 1.00 205.75 ? 115  LEU A N   1 
ATOM   691  C CA  . LEU A 1 97   ? 184.786 209.635 151.674 1.00 201.06 ? 115  LEU A CA  1 
ATOM   692  C C   . LEU A 1 97   ? 183.552 209.082 152.366 1.00 196.27 ? 115  LEU A C   1 
ATOM   693  O O   . LEU A 1 97   ? 182.454 209.622 152.198 1.00 195.97 ? 115  LEU A O   1 
ATOM   694  C CB  . LEU A 1 97   ? 185.221 208.693 150.538 1.00 197.15 ? 115  LEU A CB  1 
ATOM   695  C CG  . LEU A 1 97   ? 184.186 208.339 149.462 1.00 195.51 ? 115  LEU A CG  1 
ATOM   696  C CD1 . LEU A 1 97   ? 183.704 209.584 148.733 1.00 197.61 ? 115  LEU A CD1 1 
ATOM   697  C CD2 . LEU A 1 97   ? 184.773 207.341 148.479 1.00 196.77 ? 115  LEU A CD2 1 
ATOM   698  N N   . PHE A 1 98   ? 183.700 208.012 153.143 1.00 192.80 ? 116  PHE A N   1 
ATOM   699  C CA  . PHE A 1 98   ? 182.588 207.504 153.934 1.00 186.88 ? 116  PHE A CA  1 
ATOM   700  C C   . PHE A 1 98   ? 183.133 206.646 155.064 1.00 181.51 ? 116  PHE A C   1 
ATOM   701  O O   . PHE A 1 98   ? 184.268 206.168 155.014 1.00 181.23 ? 116  PHE A O   1 
ATOM   702  C CB  . PHE A 1 98   ? 181.599 206.706 153.076 1.00 182.39 ? 116  PHE A CB  1 
ATOM   703  C CG  . PHE A 1 98   ? 182.135 205.388 152.595 1.00 180.51 ? 116  PHE A CG  1 
ATOM   704  C CD1 . PHE A 1 98   ? 182.949 205.324 151.479 1.00 177.60 ? 116  PHE A CD1 1 
ATOM   705  C CD2 . PHE A 1 98   ? 181.817 204.213 153.254 1.00 179.13 ? 116  PHE A CD2 1 
ATOM   706  C CE1 . PHE A 1 98   ? 183.437 204.116 151.030 1.00 173.07 ? 116  PHE A CE1 1 
ATOM   707  C CE2 . PHE A 1 98   ? 182.308 203.002 152.812 1.00 178.18 ? 116  PHE A CE2 1 
ATOM   708  C CZ  . PHE A 1 98   ? 183.119 202.954 151.698 1.00 174.98 ? 116  PHE A CZ  1 
ATOM   709  N N   . SER A 1 99   ? 182.299 206.450 156.082 1.00 175.22 ? 117  SER A N   1 
ATOM   710  C CA  . SER A 1 99   ? 182.671 205.626 157.228 1.00 175.64 ? 117  SER A CA  1 
ATOM   711  C C   . SER A 1 99   ? 181.399 205.196 157.935 1.00 176.44 ? 117  SER A C   1 
ATOM   712  O O   . SER A 1 99   ? 180.605 206.049 158.346 1.00 178.71 ? 117  SER A O   1 
ATOM   713  C CB  . SER A 1 99   ? 183.587 206.392 158.181 1.00 176.53 ? 117  SER A CB  1 
ATOM   714  O OG  . SER A 1 99   ? 183.867 205.626 159.340 1.00 174.58 ? 117  SER A OG  1 
ATOM   715  N N   . ASN A 1 100  ? 181.198 203.887 158.072 1.00 174.85 ? 118  ASN A N   1 
ATOM   716  C CA  . ASN A 1 100  ? 180.012 203.380 158.747 1.00 171.97 ? 118  ASN A CA  1 
ATOM   717  C C   . ASN A 1 100  ? 180.308 201.995 159.299 1.00 164.84 ? 118  ASN A C   1 
ATOM   718  O O   . ASN A 1 100  ? 181.126 201.254 158.749 1.00 165.07 ? 118  ASN A O   1 
ATOM   719  C CB  . ASN A 1 100  ? 178.805 203.329 157.801 1.00 172.73 ? 118  ASN A CB  1 
ATOM   720  C CG  . ASN A 1 100  ? 177.475 203.038 158.541 1.00 176.61 ? 118  ASN A CG  1 
ATOM   721  O OD1 . ASN A 1 100  ? 177.372 201.996 159.189 1.00 171.78 ? 118  ASN A OD1 1 
ATOM   722  N ND2 . ASN A 1 100  ? 176.463 203.928 158.456 1.00 184.51 ? 118  ASN A ND2 1 
ATOM   723  N N   . SER A 1 101  ? 179.611 201.650 160.382 1.00 159.71 ? 119  SER A N   1 
ATOM   724  C CA  . SER A 1 101  ? 179.750 200.359 161.037 1.00 156.04 ? 119  SER A CA  1 
ATOM   725  C C   . SER A 1 101  ? 178.377 199.752 161.281 1.00 156.30 ? 119  SER A C   1 
ATOM   726  O O   . SER A 1 101  ? 177.383 200.466 161.440 1.00 160.11 ? 119  SER A O   1 
ATOM   727  C CB  . SER A 1 101  ? 180.507 200.480 162.364 1.00 161.07 ? 119  SER A CB  1 
ATOM   728  O OG  . SER A 1 101  ? 179.676 201.021 163.376 1.00 165.76 ? 119  SER A OG  1 
ATOM   729  N N   . THR A 1 102  ? 178.335 198.420 161.304 1.00 155.54 ? 120  THR A N   1 
ATOM   730  C CA  . THR A 1 102  ? 177.094 197.684 161.508 1.00 154.64 ? 120  THR A CA  1 
ATOM   731  C C   . THR A 1 102  ? 177.375 196.406 162.284 1.00 154.13 ? 120  THR A C   1 
ATOM   732  O O   . THR A 1 102  ? 178.519 195.971 162.418 1.00 154.34 ? 120  THR A O   1 
ATOM   733  C CB  . THR A 1 102  ? 176.411 197.348 160.178 1.00 148.21 ? 120  THR A CB  1 
ATOM   734  O OG1 . THR A 1 102  ? 175.054 196.956 160.421 1.00 152.30 ? 120  THR A OG1 1 
ATOM   735  C CG2 . THR A 1 102  ? 177.138 196.218 159.463 1.00 144.42 ? 120  THR A CG2 1 
ATOM   736  N N   . ARG A 1 103  ? 176.305 195.802 162.790 1.00 149.90 ? 121  ARG A N   1 
ATOM   737  C CA  . ARG A 1 103  ? 176.387 194.529 163.488 1.00 146.94 ? 121  ARG A CA  1 
ATOM   738  C C   . ARG A 1 103  ? 176.508 193.381 162.490 1.00 142.20 ? 121  ARG A C   1 
ATOM   739  O O   . ARG A 1 103  ? 176.107 193.492 161.329 1.00 139.58 ? 121  ARG A O   1 
ATOM   740  C CB  . ARG A 1 103  ? 175.149 194.326 164.361 1.00 147.16 ? 121  ARG A CB  1 
ATOM   741  C CG  . ARG A 1 103  ? 175.077 195.268 165.575 1.00 155.61 ? 121  ARG A CG  1 
ATOM   742  C CD  . ARG A 1 103  ? 175.669 194.707 166.878 1.00 164.33 ? 121  ARG A CD  1 
ATOM   743  N NE  . ARG A 1 103  ? 175.245 193.345 167.188 1.00 171.34 ? 121  ARG A NE  1 
ATOM   744  C CZ  . ARG A 1 103  ? 174.087 193.012 167.746 1.00 178.06 ? 121  ARG A CZ  1 
ATOM   745  N NH1 . ARG A 1 103  ? 173.179 193.921 168.073 1.00 174.88 ? 121  ARG A NH1 1 
ATOM   746  N NH2 . ARG A 1 103  ? 173.827 191.729 167.980 1.00 182.85 ? 121  ARG A NH2 1 
ATOM   747  N N   . LEU A 1 104  ? 177.070 192.264 162.960 1.00 141.49 ? 122  LEU A N   1 
ATOM   748  C CA  . LEU A 1 104  ? 177.153 191.033 162.182 1.00 134.69 ? 122  LEU A CA  1 
ATOM   749  C C   . LEU A 1 104  ? 176.564 189.889 162.991 1.00 137.77 ? 122  LEU A C   1 
ATOM   750  O O   . LEU A 1 104  ? 176.891 189.726 164.171 1.00 144.31 ? 122  LEU A O   1 
ATOM   751  C CB  . LEU A 1 104  ? 178.600 190.702 161.796 1.00 130.38 ? 122  LEU A CB  1 
ATOM   752  C CG  . LEU A 1 104  ? 179.347 191.619 160.820 1.00 129.91 ? 122  LEU A CG  1 
ATOM   753  C CD1 . LEU A 1 104  ? 180.703 191.012 160.493 1.00 129.67 ? 122  LEU A CD1 1 
ATOM   754  C CD2 . LEU A 1 104  ? 178.561 191.870 159.541 1.00 130.33 ? 122  LEU A CD2 1 
ATOM   755  N N   . SER A 1 105  ? 175.702 189.101 162.355 1.00 134.90 ? 123  SER A N   1 
ATOM   756  C CA  . SER A 1 105  ? 175.111 187.942 163.005 1.00 135.55 ? 123  SER A CA  1 
ATOM   757  C C   . SER A 1 105  ? 176.115 186.800 163.059 1.00 135.31 ? 123  SER A C   1 
ATOM   758  O O   . SER A 1 105  ? 176.829 186.535 162.089 1.00 137.20 ? 123  SER A O   1 
ATOM   759  C CB  . SER A 1 105  ? 173.853 187.497 162.260 1.00 137.52 ? 123  SER A CB  1 
ATOM   760  O OG  . SER A 1 105  ? 172.902 188.545 162.202 1.00 146.66 ? 123  SER A OG  1 
ATOM   761  N N   . PHE A 1 106  ? 176.155 186.117 164.199 1.00 137.27 ? 124  PHE A N   1 
ATOM   762  C CA  . PHE A 1 106  ? 177.126 185.060 164.441 1.00 138.34 ? 124  PHE A CA  1 
ATOM   763  C C   . PHE A 1 106  ? 176.545 183.701 164.073 1.00 139.89 ? 124  PHE A C   1 
ATOM   764  O O   . PHE A 1 106  ? 175.404 183.386 164.425 1.00 140.87 ? 124  PHE A O   1 
ATOM   765  C CB  . PHE A 1 106  ? 177.554 185.060 165.908 1.00 139.52 ? 124  PHE A CB  1 
ATOM   766  C CG  . PHE A 1 106  ? 178.782 184.245 166.180 1.00 139.63 ? 124  PHE A CG  1 
ATOM   767  C CD1 . PHE A 1 106  ? 180.041 184.782 165.984 1.00 143.02 ? 124  PHE A CD1 1 
ATOM   768  C CD2 . PHE A 1 106  ? 178.677 182.943 166.636 1.00 140.42 ? 124  PHE A CD2 1 
ATOM   769  C CE1 . PHE A 1 106  ? 181.172 184.035 166.236 1.00 146.89 ? 124  PHE A CE1 1 
ATOM   770  C CE2 . PHE A 1 106  ? 179.805 182.192 166.890 1.00 143.73 ? 124  PHE A CE2 1 
ATOM   771  C CZ  . PHE A 1 106  ? 181.054 182.738 166.689 1.00 147.45 ? 124  PHE A CZ  1 
ATOM   772  N N   . GLU A 1 107  ? 177.339 182.905 163.361 1.00 139.71 ? 125  GLU A N   1 
ATOM   773  C CA  . GLU A 1 107  ? 177.003 181.530 163.012 1.00 138.06 ? 125  GLU A CA  1 
ATOM   774  C C   . GLU A 1 107  ? 177.916 180.584 163.775 1.00 137.81 ? 125  GLU A C   1 
ATOM   775  O O   . GLU A 1 107  ? 179.143 180.716 163.716 1.00 140.98 ? 125  GLU A O   1 
ATOM   776  C CB  . GLU A 1 107  ? 177.144 181.292 161.506 1.00 130.79 ? 125  GLU A CB  1 
ATOM   777  C CG  . GLU A 1 107  ? 175.851 181.416 160.717 1.00 139.82 ? 125  GLU A CG  1 
ATOM   778  C CD  . GLU A 1 107  ? 175.560 182.840 160.313 1.00 146.79 ? 125  GLU A CD  1 
ATOM   779  O OE1 . GLU A 1 107  ? 175.925 183.760 161.075 1.00 146.70 ? 125  GLU A OE1 1 
ATOM   780  O OE2 . GLU A 1 107  ? 174.962 183.039 159.238 1.00 153.92 ? 125  GLU A OE2 1 
ATOM   781  N N   . THR A 1 108  ? 177.316 179.631 164.484 1.00 133.97 ? 126  THR A N   1 
ATOM   782  C CA  . THR A 1 108  ? 178.084 178.688 165.282 1.00 138.37 ? 126  THR A CA  1 
ATOM   783  C C   . THR A 1 108  ? 178.755 177.606 164.447 1.00 139.26 ? 126  THR A C   1 
ATOM   784  O O   . THR A 1 108  ? 179.738 177.017 164.909 1.00 141.18 ? 126  THR A O   1 
ATOM   785  C CB  . THR A 1 108  ? 177.182 178.033 166.334 1.00 141.75 ? 126  THR A CB  1 
ATOM   786  O OG1 . THR A 1 108  ? 177.988 177.352 167.304 1.00 138.84 ? 126  THR A OG1 1 
ATOM   787  C CG2 . THR A 1 108  ? 176.217 177.042 165.690 1.00 140.39 ? 126  THR A CG2 1 
ATOM   788  N N   . LYS A 1 109  ? 178.265 177.333 163.240 1.00 130.27 ? 127  LYS A N   1 
ATOM   789  C CA  . LYS A 1 109  ? 178.840 176.298 162.391 1.00 121.24 ? 127  LYS A CA  1 
ATOM   790  C C   . LYS A 1 109  ? 180.060 176.863 161.678 1.00 117.06 ? 127  LYS A C   1 
ATOM   791  O O   . LYS A 1 109  ? 179.958 177.870 160.969 1.00 120.71 ? 127  LYS A O   1 
ATOM   792  C CB  . LYS A 1 109  ? 177.816 175.789 161.380 1.00 122.45 ? 127  LYS A CB  1 
ATOM   793  C CG  . LYS A 1 109  ? 178.298 174.568 160.595 1.00 124.67 ? 127  LYS A CG  1 
ATOM   794  C CD  . LYS A 1 109  ? 177.209 173.511 160.400 1.00 127.48 ? 127  LYS A CD  1 
ATOM   795  C CE  . LYS A 1 109  ? 177.796 172.145 160.069 1.00 117.79 ? 127  LYS A CE  1 
ATOM   796  N NZ  . LYS A 1 109  ? 178.583 171.566 161.193 1.00 109.92 ? 127  LYS A NZ  1 
ATOM   797  N N   . ARG A 1 110  ? 181.207 176.209 161.867 1.00 109.69 ? 128  ARG A N   1 
ATOM   798  C CA  . ARG A 1 110  ? 182.483 176.676 161.334 1.00 110.83 ? 128  ARG A CA  1 
ATOM   799  C C   . ARG A 1 110  ? 183.227 175.578 160.583 1.00 111.37 ? 128  ARG A C   1 
ATOM   800  O O   . ARG A 1 110  ? 183.989 175.873 159.658 1.00 115.38 ? 128  ARG A O   1 
ATOM   801  C CB  . ARG A 1 110  ? 183.359 177.227 162.463 1.00 110.04 ? 128  ARG A CB  1 
ATOM   802  C CG  . ARG A 1 110  ? 183.647 176.257 163.607 1.00 110.44 ? 128  ARG A CG  1 
ATOM   803  C CD  . ARG A 1 110  ? 183.875 177.009 164.904 1.00 116.61 ? 128  ARG A CD  1 
ATOM   804  N NE  . ARG A 1 110  ? 182.623 177.484 165.481 1.00 121.00 ? 128  ARG A NE  1 
ATOM   805  C CZ  . ARG A 1 110  ? 182.515 178.146 166.627 1.00 134.87 ? 128  ARG A CZ  1 
ATOM   806  N NH1 . ARG A 1 110  ? 183.576 178.446 167.363 1.00 138.93 ? 128  ARG A NH1 1 
ATOM   807  N NH2 . ARG A 1 110  ? 181.311 178.519 167.047 1.00 140.06 ? 128  ARG A NH2 1 
ATOM   808  N N   . ILE A 1 111  ? 183.026 174.317 160.973 1.00 105.72 ? 129  ILE A N   1 
ATOM   809  C CA  . ILE A 1 111  ? 183.669 173.173 160.336 1.00 96.49  ? 129  ILE A CA  1 
ATOM   810  C C   . ILE A 1 111  ? 182.638 172.067 160.154 1.00 99.18  ? 129  ILE A C   1 
ATOM   811  O O   . ILE A 1 111  ? 181.584 172.054 160.790 1.00 106.16 ? 129  ILE A O   1 
ATOM   812  C CB  . ILE A 1 111  ? 184.880 172.656 161.142 1.00 88.59  ? 129  ILE A CB  1 
ATOM   813  C CG1 . ILE A 1 111  ? 184.515 172.454 162.617 1.00 95.30  ? 129  ILE A CG1 1 
ATOM   814  C CG2 . ILE A 1 111  ? 186.048 173.623 161.013 1.00 95.83  ? 129  ILE A CG2 1 
ATOM   815  C CD1 . ILE A 1 111  ? 185.574 171.732 163.407 1.00 103.97 ? 129  ILE A CD1 1 
ATOM   816  N N   . SER A 1 112  ? 182.966 171.128 159.269 1.00 98.40  ? 130  SER A N   1 
ATOM   817  C CA  . SER A 1 112  ? 182.123 169.977 158.979 1.00 96.95  ? 130  SER A CA  1 
ATOM   818  C C   . SER A 1 112  ? 182.619 168.780 159.775 1.00 94.71  ? 130  SER A C   1 
ATOM   819  O O   . SER A 1 112  ? 183.827 168.527 159.832 1.00 102.19 ? 130  SER A O   1 
ATOM   820  C CB  . SER A 1 112  ? 182.139 169.652 157.485 1.00 100.67 ? 130  SER A CB  1 
ATOM   821  O OG  . SER A 1 112  ? 181.812 170.791 156.711 1.00 113.96 ? 130  SER A OG  1 
ATOM   822  N N   . VAL A 1 113  ? 181.691 168.060 160.399 1.00 90.45  ? 131  VAL A N   1 
ATOM   823  C CA  . VAL A 1 113  ? 181.996 166.851 161.154 1.00 84.38  ? 131  VAL A CA  1 
ATOM   824  C C   . VAL A 1 113  ? 181.031 165.765 160.705 1.00 88.47  ? 131  VAL A C   1 
ATOM   825  O O   . VAL A 1 113  ? 179.811 165.917 160.848 1.00 93.24  ? 131  VAL A O   1 
ATOM   826  C CB  . VAL A 1 113  ? 181.903 167.084 162.669 1.00 82.44  ? 131  VAL A CB  1 
ATOM   827  C CG1 . VAL A 1 113  ? 182.022 165.766 163.421 1.00 84.57  ? 131  VAL A CG1 1 
ATOM   828  C CG2 . VAL A 1 113  ? 182.984 168.059 163.114 1.00 88.09  ? 131  VAL A CG2 1 
ATOM   829  N N   . PHE A 1 114  ? 181.576 164.676 160.166 1.00 86.49  ? 132  PHE A N   1 
ATOM   830  C CA  . PHE A 1 114  ? 180.805 163.510 159.754 1.00 81.89  ? 132  PHE A CA  1 
ATOM   831  C C   . PHE A 1 114  ? 181.099 162.353 160.696 1.00 85.08  ? 132  PHE A C   1 
ATOM   832  O O   . PHE A 1 114  ? 182.263 162.090 161.022 1.00 91.10  ? 132  PHE A O   1 
ATOM   833  C CB  . PHE A 1 114  ? 181.132 163.098 158.317 1.00 82.21  ? 132  PHE A CB  1 
ATOM   834  C CG  . PHE A 1 114  ? 180.899 164.175 157.302 1.00 84.89  ? 132  PHE A CG  1 
ATOM   835  C CD1 . PHE A 1 114  ? 179.641 164.375 156.765 1.00 93.40  ? 132  PHE A CD1 1 
ATOM   836  C CD2 . PHE A 1 114  ? 181.939 164.978 156.874 1.00 92.37  ? 132  PHE A CD2 1 
ATOM   837  C CE1 . PHE A 1 114  ? 179.424 165.361 155.828 1.00 109.26 ? 132  PHE A CE1 1 
ATOM   838  C CE2 . PHE A 1 114  ? 181.726 165.966 155.937 1.00 102.09 ? 132  PHE A CE2 1 
ATOM   839  C CZ  . PHE A 1 114  ? 180.468 166.157 155.413 1.00 110.44 ? 132  PHE A CZ  1 
ATOM   840  N N   . ILE A 1 115  ? 180.041 161.674 161.127 1.00 81.32  ? 133  ILE A N   1 
ATOM   841  C CA  . ILE A 1 115  ? 180.128 160.463 161.935 1.00 79.47  ? 133  ILE A CA  1 
ATOM   842  C C   . ILE A 1 115  ? 179.609 159.329 161.064 1.00 83.02  ? 133  ILE A C   1 
ATOM   843  O O   . ILE A 1 115  ? 178.414 159.277 160.749 1.00 95.82  ? 133  ILE A O   1 
ATOM   844  C CB  . ILE A 1 115  ? 179.324 160.571 163.241 1.00 81.13  ? 133  ILE A CB  1 
ATOM   845  C CG1 . ILE A 1 115  ? 179.431 161.962 163.896 1.00 82.50  ? 133  ILE A CG1 1 
ATOM   846  C CG2 . ILE A 1 115  ? 179.751 159.485 164.219 1.00 81.57  ? 133  ILE A CG2 1 
ATOM   847  C CD1 . ILE A 1 115  ? 180.807 162.339 164.387 1.00 81.45  ? 133  ILE A CD1 1 
ATOM   848  N N   . GLN A 1 116  ? 180.499 158.419 160.679 1.00 76.61  ? 134  GLN A N   1 
ATOM   849  C CA  . GLN A 1 116  ? 180.197 157.340 159.743 1.00 84.62  ? 134  GLN A CA  1 
ATOM   850  C C   . GLN A 1 116  ? 180.207 156.031 160.516 1.00 91.99  ? 134  GLN A C   1 
ATOM   851  O O   . GLN A 1 116  ? 181.278 155.488 160.789 1.00 98.72  ? 134  GLN A O   1 
ATOM   852  C CB  . GLN A 1 116  ? 181.227 157.314 158.613 1.00 86.62  ? 134  GLN A CB  1 
ATOM   853  C CG  . GLN A 1 116  ? 181.063 156.195 157.572 1.00 93.94  ? 134  GLN A CG  1 
ATOM   854  C CD  . GLN A 1 116  ? 182.265 156.061 156.657 1.00 99.55  ? 134  GLN A CD  1 
ATOM   855  O OE1 . GLN A 1 116  ? 183.330 156.615 156.922 1.00 98.71  ? 134  GLN A OE1 1 
ATOM   856  N NE2 . GLN A 1 116  ? 182.099 155.311 155.575 1.00 106.74 ? 134  GLN A NE2 1 
ATOM   857  N N   . THR A 1 117  ? 179.027 155.528 160.857 1.00 93.66  ? 135  THR A N   1 
ATOM   858  C CA  . THR A 1 117  ? 178.878 154.204 161.444 1.00 90.52  ? 135  THR A CA  1 
ATOM   859  C C   . THR A 1 117  ? 178.538 153.198 160.352 1.00 95.93  ? 135  THR A C   1 
ATOM   860  O O   . THR A 1 117  ? 177.915 153.531 159.342 1.00 107.09 ? 135  THR A O   1 
ATOM   861  C CB  . THR A 1 117  ? 177.793 154.196 162.524 1.00 90.89  ? 135  THR A CB  1 
ATOM   862  O OG1 . THR A 1 117  ? 176.502 154.115 161.910 1.00 107.66 ? 135  THR A OG1 1 
ATOM   863  C CG2 . THR A 1 117  ? 177.874 155.449 163.381 1.00 81.74  ? 135  THR A CG2 1 
ATOM   864  N N   . ASP A 1 118  ? 178.966 151.952 160.565 1.00 90.03  ? 136  ASP A N   1 
ATOM   865  C CA  . ASP A 1 118  ? 178.787 150.931 159.537 1.00 92.84  ? 136  ASP A CA  1 
ATOM   866  C C   . ASP A 1 118  ? 177.314 150.625 159.289 1.00 99.45  ? 136  ASP A C   1 
ATOM   867  O O   . ASP A 1 118  ? 176.948 150.217 158.181 1.00 110.65 ? 136  ASP A O   1 
ATOM   868  C CB  . ASP A 1 118  ? 179.535 149.653 159.920 1.00 92.74  ? 136  ASP A CB  1 
ATOM   869  C CG  . ASP A 1 118  ? 179.087 149.087 161.252 1.00 105.48 ? 136  ASP A CG  1 
ATOM   870  O OD1 . ASP A 1 118  ? 178.301 149.758 161.950 1.00 108.14 ? 136  ASP A OD1 1 
ATOM   871  O OD2 . ASP A 1 118  ? 179.523 147.970 161.601 1.00 109.04 ? 136  ASP A OD2 1 
ATOM   872  N N   . LYS A 1 119  ? 176.461 150.808 160.293 1.00 91.96  ? 137  LYS A N   1 
ATOM   873  C CA  . LYS A 1 119  ? 175.030 150.609 160.124 1.00 94.08  ? 137  LYS A CA  1 
ATOM   874  C C   . LYS A 1 119  ? 174.306 151.414 161.193 1.00 95.77  ? 137  LYS A C   1 
ATOM   875  O O   . LYS A 1 119  ? 174.906 151.869 162.168 1.00 100.61 ? 137  LYS A O   1 
ATOM   876  C CB  . LYS A 1 119  ? 174.643 149.123 160.195 1.00 100.25 ? 137  LYS A CB  1 
ATOM   877  C CG  . LYS A 1 119  ? 175.445 148.281 161.180 1.00 96.50  ? 137  LYS A CG  1 
ATOM   878  C CD  . LYS A 1 119  ? 174.969 146.835 161.175 1.00 100.36 ? 137  LYS A CD  1 
ATOM   879  C CE  . LYS A 1 119  ? 175.791 145.957 162.109 1.00 94.93  ? 137  LYS A CE  1 
ATOM   880  N NZ  . LYS A 1 119  ? 177.235 145.908 161.750 1.00 98.50  ? 137  LYS A NZ  1 
ATOM   881  N N   . ALA A 1 120  ? 173.001 151.597 160.989 1.00 90.00  ? 138  ALA A N   1 
ATOM   882  C CA  . ALA A 1 120  ? 172.163 152.359 161.906 1.00 87.07  ? 138  ALA A CA  1 
ATOM   883  C C   . ALA A 1 120  ? 171.443 151.493 162.932 1.00 89.21  ? 138  ALA A C   1 
ATOM   884  O O   . ALA A 1 120  ? 170.942 152.034 163.923 1.00 93.94  ? 138  ALA A O   1 
ATOM   885  C CB  . ALA A 1 120  ? 171.126 153.168 161.120 1.00 99.60  ? 138  ALA A CB  1 
ATOM   886  N N   . LEU A 1 121  ? 171.373 150.179 162.720 1.00 90.02  ? 139  LEU A N   1 
ATOM   887  C CA  . LEU A 1 121  ? 170.727 149.245 163.633 1.00 86.30  ? 139  LEU A CA  1 
ATOM   888  C C   . LEU A 1 121  ? 171.750 148.217 164.086 1.00 95.11  ? 139  LEU A C   1 
ATOM   889  O O   . LEU A 1 121  ? 172.430 147.611 163.252 1.00 106.08 ? 139  LEU A O   1 
ATOM   890  C CB  . LEU A 1 121  ? 169.546 148.546 162.955 1.00 90.26  ? 139  LEU A CB  1 
ATOM   891  C CG  . LEU A 1 121  ? 168.133 149.043 163.268 1.00 96.05  ? 139  LEU A CG  1 
ATOM   892  C CD1 . LEU A 1 121  ? 167.735 148.710 164.698 1.00 97.62  ? 139  LEU A CD1 1 
ATOM   893  C CD2 . LEU A 1 121  ? 167.993 150.535 162.994 1.00 100.48 ? 139  LEU A CD2 1 
ATOM   894  N N   . TYR A 1 122  ? 171.855 148.021 165.401 1.00 91.02  ? 140  TYR A N   1 
ATOM   895  C CA  . TYR A 1 122  ? 172.789 147.071 165.990 1.00 89.58  ? 140  TYR A CA  1 
ATOM   896  C C   . TYR A 1 122  ? 172.051 146.143 166.940 1.00 94.05  ? 140  TYR A C   1 
ATOM   897  O O   . TYR A 1 122  ? 171.206 146.585 167.722 1.00 97.66  ? 140  TYR A O   1 
ATOM   898  C CB  . TYR A 1 122  ? 173.902 147.776 166.761 1.00 88.51  ? 140  TYR A CB  1 
ATOM   899  C CG  . TYR A 1 122  ? 174.803 148.631 165.913 1.00 87.91  ? 140  TYR A CG  1 
ATOM   900  C CD1 . TYR A 1 122  ? 175.937 148.102 165.318 1.00 88.18  ? 140  TYR A CD1 1 
ATOM   901  C CD2 . TYR A 1 122  ? 174.521 149.970 165.707 1.00 89.21  ? 140  TYR A CD2 1 
ATOM   902  C CE1 . TYR A 1 122  ? 176.763 148.884 164.543 1.00 92.80  ? 140  TYR A CE1 1 
ATOM   903  C CE2 . TYR A 1 122  ? 175.341 150.759 164.941 1.00 95.48  ? 140  TYR A CE2 1 
ATOM   904  C CZ  . TYR A 1 122  ? 176.459 150.213 164.359 1.00 98.02  ? 140  TYR A CZ  1 
ATOM   905  O OH  . TYR A 1 122  ? 177.277 151.003 163.588 1.00 103.44 ? 140  TYR A OH  1 
ATOM   906  N N   . LYS A 1 123  ? 172.380 144.858 166.870 1.00 92.50  ? 141  LYS A N   1 
ATOM   907  C CA  . LYS A 1 123  ? 171.908 143.914 167.861 1.00 95.05  ? 141  LYS A CA  1 
ATOM   908  C C   . LYS A 1 123  ? 172.698 144.096 169.157 1.00 95.77  ? 141  LYS A C   1 
ATOM   909  O O   . LYS A 1 123  ? 173.745 144.744 169.165 1.00 98.59  ? 141  LYS A O   1 
ATOM   910  C CB  . LYS A 1 123  ? 172.066 142.484 167.358 1.00 98.35  ? 141  LYS A CB  1 
ATOM   911  C CG  . LYS A 1 123  ? 171.223 142.142 166.145 1.00 107.27 ? 141  LYS A CG  1 
ATOM   912  C CD  . LYS A 1 123  ? 171.251 140.647 165.874 1.00 114.35 ? 141  LYS A CD  1 
ATOM   913  C CE  . LYS A 1 123  ? 170.695 140.313 164.502 1.00 135.69 ? 141  LYS A CE  1 
ATOM   914  N NZ  . LYS A 1 123  ? 170.648 138.843 164.263 1.00 141.59 ? 141  LYS A NZ  1 
ATOM   915  N N   . PRO A 1 124  ? 172.212 143.554 170.272 1.00 98.83  ? 142  PRO A N   1 
ATOM   916  C CA  . PRO A 1 124  ? 173.062 143.475 171.462 1.00 99.21  ? 142  PRO A CA  1 
ATOM   917  C C   . PRO A 1 124  ? 174.276 142.592 171.222 1.00 100.47 ? 142  PRO A C   1 
ATOM   918  O O   . PRO A 1 124  ? 174.241 141.643 170.436 1.00 100.43 ? 142  PRO A O   1 
ATOM   919  C CB  . PRO A 1 124  ? 172.135 142.872 172.520 1.00 98.14  ? 142  PRO A CB  1 
ATOM   920  C CG  . PRO A 1 124  ? 170.782 143.278 172.092 1.00 103.39 ? 142  PRO A CG  1 
ATOM   921  C CD  . PRO A 1 124  ? 170.814 143.217 170.593 1.00 105.20 ? 142  PRO A CD  1 
ATOM   922  N N   . LYS A 1 125  ? 175.363 142.922 171.918 1.00 101.70 ? 143  LYS A N   1 
ATOM   923  C CA  . LYS A 1 125  ? 176.612 142.164 171.833 1.00 99.96  ? 143  LYS A CA  1 
ATOM   924  C C   . LYS A 1 125  ? 177.199 142.194 170.422 1.00 100.30 ? 143  LYS A C   1 
ATOM   925  O O   . LYS A 1 125  ? 177.813 141.227 169.967 1.00 106.60 ? 143  LYS A O   1 
ATOM   926  C CB  . LYS A 1 125  ? 176.408 140.723 172.309 1.00 109.01 ? 143  LYS A CB  1 
ATOM   927  C CG  . LYS A 1 125  ? 177.587 140.155 173.089 1.00 116.32 ? 143  LYS A CG  1 
ATOM   928  C CD  . LYS A 1 125  ? 177.739 138.647 172.897 1.00 127.71 ? 143  LYS A CD  1 
ATOM   929  C CE  . LYS A 1 125  ? 176.492 137.864 173.307 1.00 139.48 ? 143  LYS A CE  1 
ATOM   930  N NZ  . LYS A 1 125  ? 176.016 138.208 174.676 1.00 133.83 ? 143  LYS A NZ  1 
ATOM   931  N N   . GLN A 1 126  ? 177.019 143.317 169.731 1.00 101.38 ? 144  GLN A N   1 
ATOM   932  C CA  . GLN A 1 126  ? 177.645 143.588 168.445 1.00 94.31  ? 144  GLN A CA  1 
ATOM   933  C C   . GLN A 1 126  ? 178.651 144.719 168.609 1.00 95.98  ? 144  GLN A C   1 
ATOM   934  O O   . GLN A 1 126  ? 178.690 145.402 169.635 1.00 103.08 ? 144  GLN A O   1 
ATOM   935  C CB  . GLN A 1 126  ? 176.594 143.946 167.389 1.00 88.93  ? 144  GLN A CB  1 
ATOM   936  C CG  . GLN A 1 126  ? 176.137 142.764 166.549 1.00 93.11  ? 144  GLN A CG  1 
ATOM   937  C CD  . GLN A 1 126  ? 175.223 143.176 165.415 1.00 99.68  ? 144  GLN A CD  1 
ATOM   938  O OE1 . GLN A 1 126  ? 174.431 144.107 165.549 1.00 95.63  ? 144  GLN A OE1 1 
ATOM   939  N NE2 . GLN A 1 126  ? 175.324 142.478 164.290 1.00 106.02 ? 144  GLN A NE2 1 
ATOM   940  N N   . GLU A 1 127  ? 179.472 144.907 167.580 1.00 92.46  ? 145  GLU A N   1 
ATOM   941  C CA  . GLU A 1 127  ? 180.557 145.880 167.591 1.00 96.87  ? 145  GLU A CA  1 
ATOM   942  C C   . GLU A 1 127  ? 180.168 147.066 166.723 1.00 100.08 ? 145  GLU A C   1 
ATOM   943  O O   . GLU A 1 127  ? 179.913 146.903 165.525 1.00 106.62 ? 145  GLU A O   1 
ATOM   944  C CB  . GLU A 1 127  ? 181.852 145.247 167.085 1.00 100.22 ? 145  GLU A CB  1 
ATOM   945  C CG  . GLU A 1 127  ? 183.021 146.207 167.002 1.00 103.60 ? 145  GLU A CG  1 
ATOM   946  C CD  . GLU A 1 127  ? 184.350 145.487 166.964 1.00 115.72 ? 145  GLU A CD  1 
ATOM   947  O OE1 . GLU A 1 127  ? 184.398 144.358 166.435 1.00 126.34 ? 145  GLU A OE1 1 
ATOM   948  O OE2 . GLU A 1 127  ? 185.348 146.048 167.461 1.00 116.44 ? 145  GLU A OE2 1 
ATOM   949  N N   . VAL A 1 128  ? 180.126 148.251 167.323 1.00 94.05  ? 146  VAL A N   1 
ATOM   950  C CA  . VAL A 1 128  ? 179.864 149.489 166.602 1.00 92.19  ? 146  VAL A CA  1 
ATOM   951  C C   . VAL A 1 128  ? 181.204 150.018 166.113 1.00 95.51  ? 146  VAL A C   1 
ATOM   952  O O   . VAL A 1 128  ? 182.003 150.519 166.906 1.00 95.15  ? 146  VAL A O   1 
ATOM   953  C CB  . VAL A 1 128  ? 179.159 150.521 167.491 1.00 84.18  ? 146  VAL A CB  1 
ATOM   954  C CG1 . VAL A 1 128  ? 179.010 151.841 166.751 1.00 87.51  ? 146  VAL A CG1 1 
ATOM   955  C CG2 . VAL A 1 128  ? 177.802 150.008 167.952 1.00 88.89  ? 146  VAL A CG2 1 
ATOM   956  N N   . LYS A 1 129  ? 181.456 149.893 164.815 1.00 95.34  ? 147  LYS A N   1 
ATOM   957  C CA  . LYS A 1 129  ? 182.634 150.465 164.176 1.00 92.05  ? 147  LYS A CA  1 
ATOM   958  C C   . LYS A 1 129  ? 182.230 151.800 163.575 1.00 90.07  ? 147  LYS A C   1 
ATOM   959  O O   . LYS A 1 129  ? 181.270 151.859 162.800 1.00 94.86  ? 147  LYS A O   1 
ATOM   960  C CB  . LYS A 1 129  ? 183.187 149.549 163.081 1.00 90.91  ? 147  LYS A CB  1 
ATOM   961  C CG  . LYS A 1 129  ? 182.953 148.058 163.286 1.00 94.58  ? 147  LYS A CG  1 
ATOM   962  C CD  . LYS A 1 129  ? 183.614 147.243 162.189 1.00 96.85  ? 147  LYS A CD  1 
ATOM   963  C CE  . LYS A 1 129  ? 183.171 145.792 162.235 1.00 97.68  ? 147  LYS A CE  1 
ATOM   964  N NZ  . LYS A 1 129  ? 183.815 144.973 161.172 1.00 107.25 ? 147  LYS A NZ  1 
ATOM   965  N N   . PHE A 1 130  ? 182.945 152.867 163.937 1.00 84.70  ? 148  PHE A N   1 
ATOM   966  C CA  . PHE A 1 130  ? 182.609 154.195 163.444 1.00 79.85  ? 148  PHE A CA  1 
ATOM   967  C C   . PHE A 1 130  ? 183.870 154.968 163.093 1.00 80.30  ? 148  PHE A C   1 
ATOM   968  O O   . PHE A 1 130  ? 184.983 154.609 163.485 1.00 88.63  ? 148  PHE A O   1 
ATOM   969  C CB  . PHE A 1 130  ? 181.755 154.982 164.450 1.00 79.76  ? 148  PHE A CB  1 
ATOM   970  C CG  . PHE A 1 130  ? 182.426 155.239 165.767 1.00 73.85  ? 148  PHE A CG  1 
ATOM   971  C CD1 . PHE A 1 130  ? 182.374 154.301 166.779 1.00 81.81  ? 148  PHE A CD1 1 
ATOM   972  C CD2 . PHE A 1 130  ? 183.077 156.435 166.006 1.00 73.36  ? 148  PHE A CD2 1 
ATOM   973  C CE1 . PHE A 1 130  ? 182.977 154.541 167.995 1.00 87.71  ? 148  PHE A CE1 1 
ATOM   974  C CE2 . PHE A 1 130  ? 183.682 156.680 167.220 1.00 75.68  ? 148  PHE A CE2 1 
ATOM   975  C CZ  . PHE A 1 130  ? 183.627 155.733 168.217 1.00 81.64  ? 148  PHE A CZ  1 
ATOM   976  N N   . ARG A 1 131  ? 183.668 156.019 162.301 1.00 76.39  ? 149  ARG A N   1 
ATOM   977  C CA  . ARG A 1 131  ? 184.725 156.904 161.836 1.00 73.40  ? 149  ARG A CA  1 
ATOM   978  C C   . ARG A 1 131  ? 184.305 158.343 162.082 1.00 73.76  ? 149  ARG A C   1 
ATOM   979  O O   . ARG A 1 131  ? 183.178 158.727 161.755 1.00 77.29  ? 149  ARG A O   1 
ATOM   980  C CB  . ARG A 1 131  ? 185.010 156.701 160.346 1.00 76.96  ? 149  ARG A CB  1 
ATOM   981  C CG  . ARG A 1 131  ? 186.077 155.662 160.044 1.00 79.70  ? 149  ARG A CG  1 
ATOM   982  C CD  . ARG A 1 131  ? 186.194 155.379 158.552 1.00 81.07  ? 149  ARG A CD  1 
ATOM   983  N NE  . ARG A 1 131  ? 186.358 153.952 158.291 1.00 90.40  ? 149  ARG A NE  1 
ATOM   984  C CZ  . ARG A 1 131  ? 185.888 153.290 157.238 1.00 95.38  ? 149  ARG A CZ  1 
ATOM   985  N NH1 . ARG A 1 131  ? 185.239 153.898 156.255 1.00 93.29  ? 149  ARG A NH1 1 
ATOM   986  N NH2 . ARG A 1 131  ? 186.089 151.978 157.161 1.00 97.92  ? 149  ARG A NH2 1 
ATOM   987  N N   . ILE A 1 132  ? 185.209 159.128 162.657 1.00 73.62  ? 150  ILE A N   1 
ATOM   988  C CA  . ILE A 1 132  ? 185.028 160.562 162.842 1.00 73.80  ? 150  ILE A CA  1 
ATOM   989  C C   . ILE A 1 132  ? 185.847 161.269 161.775 1.00 84.38  ? 150  ILE A C   1 
ATOM   990  O O   . ILE A 1 132  ? 187.056 161.028 161.657 1.00 93.52  ? 150  ILE A O   1 
ATOM   991  C CB  . ILE A 1 132  ? 185.467 161.010 164.247 1.00 75.43  ? 150  ILE A CB  1 
ATOM   992  C CG1 . ILE A 1 132  ? 184.929 160.064 165.331 1.00 83.82  ? 150  ILE A CG1 1 
ATOM   993  C CG2 . ILE A 1 132  ? 185.044 162.452 164.506 1.00 75.58  ? 150  ILE A CG2 1 
ATOM   994  C CD1 . ILE A 1 132  ? 183.440 159.809 165.273 1.00 83.47  ? 150  ILE A CD1 1 
ATOM   995  N N   . VAL A 1 133  ? 185.196 162.135 160.999 1.00 85.91  ? 151  VAL A N   1 
ATOM   996  C CA  . VAL A 1 133  ? 185.836 162.882 159.922 1.00 83.41  ? 151  VAL A CA  1 
ATOM   997  C C   . VAL A 1 133  ? 185.616 164.361 160.193 1.00 86.98  ? 151  VAL A C   1 
ATOM   998  O O   . VAL A 1 133  ? 184.472 164.827 160.200 1.00 92.49  ? 151  VAL A O   1 
ATOM   999  C CB  . VAL A 1 133  ? 185.274 162.491 158.546 1.00 72.45  ? 151  VAL A CB  1 
ATOM   1000 C CG1 . VAL A 1 133  ? 185.955 163.286 157.442 1.00 79.73  ? 151  VAL A CG1 1 
ATOM   1001 C CG2 . VAL A 1 133  ? 185.419 160.991 158.311 1.00 76.52  ? 151  VAL A CG2 1 
ATOM   1002 N N   . THR A 1 134  ? 186.708 165.095 160.400 1.00 86.33  ? 152  THR A N   1 
ATOM   1003 C CA  . THR A 1 134  ? 186.683 166.538 160.617 1.00 89.05  ? 152  THR A CA  1 
ATOM   1004 C C   . THR A 1 134  ? 187.252 167.214 159.379 1.00 90.34  ? 152  THR A C   1 
ATOM   1005 O O   . THR A 1 134  ? 188.327 166.832 158.905 1.00 98.68  ? 152  THR A O   1 
ATOM   1006 C CB  . THR A 1 134  ? 187.496 166.927 161.851 1.00 91.85  ? 152  THR A CB  1 
ATOM   1007 O OG1 . THR A 1 134  ? 188.893 166.821 161.557 1.00 101.98 ? 152  THR A OG1 1 
ATOM   1008 C CG2 . THR A 1 134  ? 187.161 166.022 163.024 1.00 89.14  ? 152  THR A CG2 1 
ATOM   1009 N N   . LEU A 1 135  ? 186.536 168.211 158.860 1.00 85.28  ? 153  LEU A N   1 
ATOM   1010 C CA  . LEU A 1 135  ? 186.923 168.886 157.632 1.00 84.28  ? 153  LEU A CA  1 
ATOM   1011 C C   . LEU A 1 135  ? 186.665 170.378 157.756 1.00 94.65  ? 153  LEU A C   1 
ATOM   1012 O O   . LEU A 1 135  ? 185.736 170.812 158.442 1.00 104.25 ? 153  LEU A O   1 
ATOM   1013 C CB  . LEU A 1 135  ? 186.153 168.332 156.430 1.00 82.77  ? 153  LEU A CB  1 
ATOM   1014 C CG  . LEU A 1 135  ? 186.464 166.891 156.025 1.00 87.89  ? 153  LEU A CG  1 
ATOM   1015 C CD1 . LEU A 1 135  ? 185.510 166.442 154.941 1.00 87.78  ? 153  LEU A CD1 1 
ATOM   1016 C CD2 . LEU A 1 135  ? 187.903 166.741 155.559 1.00 96.16  ? 153  LEU A CD2 1 
ATOM   1017 N N   . PHE A 1 136  ? 187.496 171.156 157.070 1.00 95.89  ? 154  PHE A N   1 
ATOM   1018 C CA  . PHE A 1 136  ? 187.319 172.596 156.978 1.00 99.14  ? 154  PHE A CA  1 
ATOM   1019 C C   . PHE A 1 136  ? 186.078 172.906 156.141 1.00 104.67 ? 154  PHE A C   1 
ATOM   1020 O O   . PHE A 1 136  ? 185.422 172.014 155.598 1.00 106.98 ? 154  PHE A O   1 
ATOM   1021 C CB  . PHE A 1 136  ? 188.568 173.240 156.377 1.00 98.56  ? 154  PHE A CB  1 
ATOM   1022 C CG  . PHE A 1 136  ? 189.601 173.629 157.389 1.00 98.42  ? 154  PHE A CG  1 
ATOM   1023 C CD1 . PHE A 1 136  ? 189.434 174.758 158.170 1.00 104.70 ? 154  PHE A CD1 1 
ATOM   1024 C CD2 . PHE A 1 136  ? 190.745 172.871 157.552 1.00 99.49  ? 154  PHE A CD2 1 
ATOM   1025 C CE1 . PHE A 1 136  ? 190.387 175.119 159.098 1.00 111.30 ? 154  PHE A CE1 1 
ATOM   1026 C CE2 . PHE A 1 136  ? 191.701 173.227 158.478 1.00 106.62 ? 154  PHE A CE2 1 
ATOM   1027 C CZ  . PHE A 1 136  ? 191.523 174.353 159.252 1.00 111.43 ? 154  PHE A CZ  1 
ATOM   1028 N N   . SER A 1 137  ? 185.741 174.194 156.037 1.00 109.65 ? 155  SER A N   1 
ATOM   1029 C CA  . SER A 1 137  ? 184.651 174.596 155.156 1.00 112.33 ? 155  SER A CA  1 
ATOM   1030 C C   . SER A 1 137  ? 184.961 174.241 153.707 1.00 109.34 ? 155  SER A C   1 
ATOM   1031 O O   . SER A 1 137  ? 184.070 173.815 152.964 1.00 111.81 ? 155  SER A O   1 
ATOM   1032 C CB  . SER A 1 137  ? 184.386 176.094 155.298 1.00 117.11 ? 155  SER A CB  1 
ATOM   1033 O OG  . SER A 1 137  ? 185.577 176.840 155.130 1.00 129.60 ? 155  SER A OG  1 
ATOM   1034 N N   . ASP A 1 138  ? 186.220 174.396 153.292 1.00 108.12 ? 156  ASP A N   1 
ATOM   1035 C CA  . ASP A 1 138  ? 186.656 174.043 151.946 1.00 108.71 ? 156  ASP A CA  1 
ATOM   1036 C C   . ASP A 1 138  ? 187.086 172.580 151.828 1.00 103.26 ? 156  ASP A C   1 
ATOM   1037 O O   . ASP A 1 138  ? 187.812 172.230 150.891 1.00 105.06 ? 156  ASP A O   1 
ATOM   1038 C CB  . ASP A 1 138  ? 187.796 174.962 151.499 1.00 115.69 ? 156  ASP A CB  1 
ATOM   1039 C CG  . ASP A 1 138  ? 189.034 174.828 152.364 1.00 119.25 ? 156  ASP A CG  1 
ATOM   1040 O OD1 . ASP A 1 138  ? 188.924 174.285 153.481 1.00 117.83 ? 156  ASP A OD1 1 
ATOM   1041 O OD2 . ASP A 1 138  ? 190.116 175.271 151.927 1.00 125.57 ? 156  ASP A OD2 1 
ATOM   1042 N N   . PHE A 1 139  ? 186.657 171.722 152.756 1.00 97.16  ? 157  PHE A N   1 
ATOM   1043 C CA  . PHE A 1 139  ? 186.805 170.268 152.684 1.00 93.67  ? 157  PHE A CA  1 
ATOM   1044 C C   . PHE A 1 139  ? 188.263 169.808 152.707 1.00 96.05  ? 157  PHE A C   1 
ATOM   1045 O O   . PHE A 1 139  ? 188.560 168.661 152.360 1.00 95.37  ? 157  PHE A O   1 
ATOM   1046 C CB  . PHE A 1 139  ? 186.066 169.698 151.458 1.00 90.53  ? 157  PHE A CB  1 
ATOM   1047 C CG  . PHE A 1 139  ? 184.602 169.461 151.698 1.00 96.59  ? 157  PHE A CG  1 
ATOM   1048 C CD1 . PHE A 1 139  ? 183.823 170.406 152.343 1.00 102.91 ? 157  PHE A CD1 1 
ATOM   1049 C CD2 . PHE A 1 139  ? 184.008 168.283 151.293 1.00 106.57 ? 157  PHE A CD2 1 
ATOM   1050 C CE1 . PHE A 1 139  ? 182.486 170.181 152.569 1.00 104.62 ? 157  PHE A CE1 1 
ATOM   1051 C CE2 . PHE A 1 139  ? 182.668 168.055 151.515 1.00 110.31 ? 157  PHE A CE2 1 
ATOM   1052 C CZ  . PHE A 1 139  ? 181.907 169.004 152.155 1.00 104.82 ? 157  PHE A CZ  1 
ATOM   1053 N N   . LYS A 1 140  ? 189.185 170.659 153.148 1.00 102.28 ? 158  LYS A N   1 
ATOM   1054 C CA  . LYS A 1 140  ? 190.522 170.190 153.468 1.00 100.32 ? 158  LYS A CA  1 
ATOM   1055 C C   . LYS A 1 140  ? 190.482 169.415 154.787 1.00 97.91  ? 158  LYS A C   1 
ATOM   1056 O O   . LYS A 1 140  ? 189.557 169.591 155.584 1.00 102.40 ? 158  LYS A O   1 
ATOM   1057 C CB  . LYS A 1 140  ? 191.491 171.364 153.589 1.00 102.84 ? 158  LYS A CB  1 
ATOM   1058 C CG  . LYS A 1 140  ? 191.614 172.230 152.341 1.00 107.04 ? 158  LYS A CG  1 
ATOM   1059 C CD  . LYS A 1 140  ? 192.976 172.067 151.685 1.00 116.47 ? 158  LYS A CD  1 
ATOM   1060 C CE  . LYS A 1 140  ? 193.015 172.713 150.312 1.00 123.71 ? 158  LYS A CE  1 
ATOM   1061 N NZ  . LYS A 1 140  ? 192.231 171.945 149.307 1.00 123.47 ? 158  LYS A NZ  1 
ATOM   1062 N N   . PRO A 1 141  ? 191.459 168.546 155.048 1.00 93.16  ? 159  PRO A N   1 
ATOM   1063 C CA  . PRO A 1 141  ? 191.512 167.905 156.365 1.00 93.90  ? 159  PRO A CA  1 
ATOM   1064 C C   . PRO A 1 141  ? 191.824 168.917 157.453 1.00 102.28 ? 159  PRO A C   1 
ATOM   1065 O O   . PRO A 1 141  ? 192.477 169.936 157.215 1.00 111.41 ? 159  PRO A O   1 
ATOM   1066 C CB  . PRO A 1 141  ? 192.636 166.874 156.221 1.00 100.99 ? 159  PRO A CB  1 
ATOM   1067 C CG  . PRO A 1 141  ? 193.470 167.380 155.123 1.00 112.06 ? 159  PRO A CG  1 
ATOM   1068 C CD  . PRO A 1 141  ? 192.533 168.049 154.170 1.00 103.43 ? 159  PRO A CD  1 
ATOM   1069 N N   . TYR A 1 142  ? 191.346 168.619 158.661 1.00 99.49  ? 160  TYR A N   1 
ATOM   1070 C CA  . TYR A 1 142  ? 191.473 169.500 159.820 1.00 96.78  ? 160  TYR A CA  1 
ATOM   1071 C C   . TYR A 1 142  ? 192.103 168.715 160.960 1.00 98.14  ? 160  TYR A C   1 
ATOM   1072 O O   . TYR A 1 142  ? 191.428 167.914 161.615 1.00 100.12 ? 160  TYR A O   1 
ATOM   1073 C CB  . TYR A 1 142  ? 190.108 170.056 160.227 1.00 92.00  ? 160  TYR A CB  1 
ATOM   1074 C CG  . TYR A 1 142  ? 190.121 170.941 161.456 1.00 101.57 ? 160  TYR A CG  1 
ATOM   1075 C CD1 . TYR A 1 142  ? 191.088 171.921 161.628 1.00 110.31 ? 160  TYR A CD1 1 
ATOM   1076 C CD2 . TYR A 1 142  ? 189.157 170.800 162.443 1.00 102.57 ? 160  TYR A CD2 1 
ATOM   1077 C CE1 . TYR A 1 142  ? 191.098 172.729 162.745 1.00 118.14 ? 160  TYR A CE1 1 
ATOM   1078 C CE2 . TYR A 1 142  ? 189.159 171.604 163.563 1.00 110.02 ? 160  TYR A CE2 1 
ATOM   1079 C CZ  . TYR A 1 142  ? 190.132 172.566 163.709 1.00 120.53 ? 160  TYR A CZ  1 
ATOM   1080 O OH  . TYR A 1 142  ? 190.140 173.370 164.824 1.00 125.15 ? 160  TYR A OH  1 
ATOM   1081 N N   . LYS A 1 143  ? 193.391 168.946 161.200 1.00 101.37 ? 161  LYS A N   1 
ATOM   1082 C CA  . LYS A 1 143  ? 194.090 168.301 162.304 1.00 107.83 ? 161  LYS A CA  1 
ATOM   1083 C C   . LYS A 1 143  ? 193.759 169.037 163.595 1.00 110.22 ? 161  LYS A C   1 
ATOM   1084 O O   . LYS A 1 143  ? 194.005 170.243 163.708 1.00 112.00 ? 161  LYS A O   1 
ATOM   1085 C CB  . LYS A 1 143  ? 195.598 168.297 162.068 1.00 111.75 ? 161  LYS A CB  1 
ATOM   1086 C CG  . LYS A 1 143  ? 196.038 167.727 160.720 1.00 115.60 ? 161  LYS A CG  1 
ATOM   1087 C CD  . LYS A 1 143  ? 196.685 168.788 159.833 1.00 123.95 ? 161  LYS A CD  1 
ATOM   1088 C CE  . LYS A 1 143  ? 197.429 168.166 158.666 1.00 136.14 ? 161  LYS A CE  1 
ATOM   1089 N NZ  . LYS A 1 143  ? 198.236 169.182 157.937 1.00 149.21 ? 161  LYS A NZ  1 
ATOM   1090 N N   . THR A 1 144  ? 193.207 168.316 164.565 1.00 114.35 ? 162  THR A N   1 
ATOM   1091 C CA  . THR A 1 144  ? 192.780 168.920 165.817 1.00 112.14 ? 162  THR A CA  1 
ATOM   1092 C C   . THR A 1 144  ? 192.681 167.846 166.888 1.00 111.72 ? 162  THR A C   1 
ATOM   1093 O O   . THR A 1 144  ? 192.639 166.648 166.598 1.00 115.94 ? 162  THR A O   1 
ATOM   1094 C CB  . THR A 1 144  ? 191.434 169.640 165.664 1.00 111.66 ? 162  THR A CB  1 
ATOM   1095 O OG1 . THR A 1 144  ? 190.951 170.033 166.955 1.00 118.46 ? 162  THR A OG1 1 
ATOM   1096 C CG2 . THR A 1 144  ? 190.395 168.743 164.983 1.00 110.17 ? 162  THR A CG2 1 
ATOM   1097 N N   . SER A 1 145  ? 192.641 168.297 168.138 1.00 111.11 ? 163  SER A N   1 
ATOM   1098 C CA  . SER A 1 145  ? 192.346 167.436 169.272 1.00 113.12 ? 163  SER A CA  1 
ATOM   1099 C C   . SER A 1 145  ? 190.845 167.440 169.519 1.00 108.43 ? 163  SER A C   1 
ATOM   1100 O O   . SER A 1 145  ? 190.189 168.478 169.396 1.00 110.91 ? 163  SER A O   1 
ATOM   1101 C CB  . SER A 1 145  ? 193.086 167.910 170.523 1.00 119.69 ? 163  SER A CB  1 
ATOM   1102 O OG  . SER A 1 145  ? 194.430 168.241 170.224 1.00 136.39 ? 163  SER A OG  1 
ATOM   1103 N N   . LEU A 1 146  ? 190.304 166.274 169.864 1.00 104.57 ? 164  LEU A N   1 
ATOM   1104 C CA  . LEU A 1 146  ? 188.868 166.132 170.048 1.00 95.56  ? 164  LEU A CA  1 
ATOM   1105 C C   . LEU A 1 146  ? 188.591 165.044 171.071 1.00 94.25  ? 164  LEU A C   1 
ATOM   1106 O O   . LEU A 1 146  ? 189.458 164.227 171.391 1.00 98.79  ? 164  LEU A O   1 
ATOM   1107 C CB  . LEU A 1 146  ? 188.159 165.813 168.725 1.00 86.33  ? 164  LEU A CB  1 
ATOM   1108 C CG  . LEU A 1 146  ? 188.141 164.379 168.185 1.00 77.77  ? 164  LEU A CG  1 
ATOM   1109 C CD1 . LEU A 1 146  ? 187.456 164.349 166.834 1.00 75.83  ? 164  LEU A CD1 1 
ATOM   1110 C CD2 . LEU A 1 146  ? 189.533 163.805 168.071 1.00 87.69  ? 164  LEU A CD2 1 
ATOM   1111 N N   . ASN A 1 147  ? 187.363 165.055 171.581 1.00 90.78  ? 165  ASN A N   1 
ATOM   1112 C CA  . ASN A 1 147  ? 186.864 164.049 172.506 1.00 89.09  ? 165  ASN A CA  1 
ATOM   1113 C C   . ASN A 1 147  ? 185.688 163.327 171.868 1.00 85.08  ? 165  ASN A C   1 
ATOM   1114 O O   . ASN A 1 147  ? 184.907 163.931 171.132 1.00 90.56  ? 165  ASN A O   1 
ATOM   1115 C CB  . ASN A 1 147  ? 186.432 164.681 173.830 1.00 89.25  ? 165  ASN A CB  1 
ATOM   1116 C CG  . ASN A 1 147  ? 187.454 165.660 174.365 1.00 98.11  ? 165  ASN A CG  1 
ATOM   1117 O OD1 . ASN A 1 147  ? 188.651 165.516 174.127 1.00 99.19  ? 165  ASN A OD1 1 
ATOM   1118 N ND2 . ASN A 1 147  ? 186.985 166.664 175.095 1.00 102.19 ? 165  ASN A ND2 1 
ATOM   1119 N N   . ILE A 1 148  ? 185.578 162.032 172.149 1.00 79.16  ? 166  ILE A N   1 
ATOM   1120 C CA  . ILE A 1 148  ? 184.489 161.188 171.670 1.00 77.77  ? 166  ILE A CA  1 
ATOM   1121 C C   . ILE A 1 148  ? 183.786 160.625 172.893 1.00 82.53  ? 166  ILE A C   1 
ATOM   1122 O O   . ILE A 1 148  ? 184.449 160.211 173.848 1.00 89.78  ? 166  ILE A O   1 
ATOM   1123 C CB  . ILE A 1 148  ? 184.999 160.056 170.759 1.00 73.35  ? 166  ILE A CB  1 
ATOM   1124 C CG1 . ILE A 1 148  ? 185.642 160.618 169.485 1.00 74.35  ? 166  ILE A CG1 1 
ATOM   1125 C CG2 . ILE A 1 148  ? 183.867 159.107 170.403 1.00 77.84  ? 166  ILE A CG2 1 
ATOM   1126 C CD1 . ILE A 1 148  ? 186.772 159.771 168.958 1.00 78.05  ? 166  ILE A CD1 1 
ATOM   1127 N N   . LEU A 1 149  ? 182.452 160.633 172.873 1.00 80.36  ? 167  LEU A N   1 
ATOM   1128 C CA  . LEU A 1 149  ? 181.636 160.221 174.010 1.00 78.14  ? 167  LEU A CA  1 
ATOM   1129 C C   . LEU A 1 149  ? 180.462 159.406 173.494 1.00 84.25  ? 167  LEU A C   1 
ATOM   1130 O O   . LEU A 1 149  ? 179.618 159.936 172.768 1.00 92.71  ? 167  LEU A O   1 
ATOM   1131 C CB  . LEU A 1 149  ? 181.124 161.440 174.785 1.00 77.38  ? 167  LEU A CB  1 
ATOM   1132 C CG  . LEU A 1 149  ? 182.131 162.325 175.523 1.00 80.87  ? 167  LEU A CG  1 
ATOM   1133 C CD1 . LEU A 1 149  ? 182.620 163.458 174.639 1.00 88.73  ? 167  LEU A CD1 1 
ATOM   1134 C CD2 . LEU A 1 149  ? 181.510 162.896 176.780 1.00 88.06  ? 167  LEU A CD2 1 
ATOM   1135 N N   . ILE A 1 150  ? 180.393 158.133 173.877 1.00 77.31  ? 168  ILE A N   1 
ATOM   1136 C CA  . ILE A 1 150  ? 179.306 157.240 173.489 1.00 69.71  ? 168  ILE A CA  1 
ATOM   1137 C C   . ILE A 1 150  ? 178.425 157.043 174.714 1.00 76.96  ? 168  ILE A C   1 
ATOM   1138 O O   . ILE A 1 150  ? 178.897 156.560 175.757 1.00 85.45  ? 168  ILE A O   1 
ATOM   1139 C CB  . ILE A 1 150  ? 179.827 155.897 172.950 1.00 64.17  ? 168  ILE A CB  1 
ATOM   1140 C CG1 . ILE A 1 150  ? 180.933 156.130 171.910 1.00 75.02  ? 168  ILE A CG1 1 
ATOM   1141 C CG2 . ILE A 1 150  ? 178.687 155.090 172.310 1.00 68.56  ? 168  ILE A CG2 1 
ATOM   1142 C CD1 . ILE A 1 150  ? 181.418 154.874 171.204 1.00 82.93  ? 168  ILE A CD1 1 
ATOM   1143 N N   . LYS A 1 151  ? 177.143 157.400 174.570 1.00 77.74  ? 169  LYS A N   1 
ATOM   1144 C CA  . LYS A 1 151  ? 176.163 157.401 175.646 1.00 83.17  ? 169  LYS A CA  1 
ATOM   1145 C C   . LYS A 1 151  ? 174.939 156.573 175.272 1.00 85.02  ? 169  LYS A C   1 
ATOM   1146 O O   . LYS A 1 151  ? 174.544 156.499 174.102 1.00 90.03  ? 169  LYS A O   1 
ATOM   1147 C CB  . LYS A 1 151  ? 175.697 158.822 175.984 1.00 80.96  ? 169  LYS A CB  1 
ATOM   1148 C CG  . LYS A 1 151  ? 176.781 159.880 175.981 1.00 81.85  ? 169  LYS A CG  1 
ATOM   1149 C CD  . LYS A 1 151  ? 176.242 161.193 176.531 1.00 87.59  ? 169  LYS A CD  1 
ATOM   1150 C CE  . LYS A 1 151  ? 177.329 162.242 176.656 1.00 96.49  ? 169  LYS A CE  1 
ATOM   1151 N NZ  . LYS A 1 151  ? 176.818 163.497 177.271 1.00 102.09 ? 169  LYS A NZ  1 
ATOM   1152 N N   . ASP A 1 152  ? 174.338 155.971 176.293 1.00 87.50  ? 170  ASP A N   1 
ATOM   1153 C CA  . ASP A 1 152  ? 173.111 155.188 176.154 1.00 89.49  ? 170  ASP A CA  1 
ATOM   1154 C C   . ASP A 1 152  ? 171.910 156.122 176.031 1.00 95.13  ? 170  ASP A C   1 
ATOM   1155 O O   . ASP A 1 152  ? 172.051 157.341 176.138 1.00 100.05 ? 170  ASP A O   1 
ATOM   1156 C CB  . ASP A 1 152  ? 172.963 154.226 177.341 1.00 95.93  ? 170  ASP A CB  1 
ATOM   1157 C CG  . ASP A 1 152  ? 173.091 154.907 178.698 1.00 106.47 ? 170  ASP A CG  1 
ATOM   1158 O OD1 . ASP A 1 152  ? 173.080 156.153 178.756 1.00 110.19 ? 170  ASP A OD1 1 
ATOM   1159 O OD2 . ASP A 1 152  ? 173.208 154.184 179.709 1.00 108.28 ? 170  ASP A OD2 1 
ATOM   1160 N N   . PRO A 1 153  ? 170.709 155.588 175.770 1.00 93.66  ? 171  PRO A N   1 
ATOM   1161 C CA  . PRO A 1 153  ? 169.529 156.466 175.690 1.00 99.39  ? 171  PRO A CA  1 
ATOM   1162 C C   . PRO A 1 153  ? 169.238 157.230 176.966 1.00 104.73 ? 171  PRO A C   1 
ATOM   1163 O O   . PRO A 1 153  ? 168.653 158.318 176.894 1.00 108.76 ? 171  PRO A O   1 
ATOM   1164 C CB  . PRO A 1 153  ? 168.395 155.492 175.352 1.00 100.61 ? 171  PRO A CB  1 
ATOM   1165 C CG  . PRO A 1 153  ? 169.058 154.423 174.592 1.00 93.50  ? 171  PRO A CG  1 
ATOM   1166 C CD  . PRO A 1 153  ? 170.397 154.246 175.243 1.00 89.68  ? 171  PRO A CD  1 
ATOM   1167 N N   . LYS A 1 154  ? 169.623 156.707 178.126 1.00 101.54 ? 172  LYS A N   1 
ATOM   1168 C CA  . LYS A 1 154  ? 169.491 157.423 179.387 1.00 106.87 ? 172  LYS A CA  1 
ATOM   1169 C C   . LYS A 1 154  ? 170.646 158.388 179.648 1.00 110.15 ? 172  LYS A C   1 
ATOM   1170 O O   . LYS A 1 154  ? 170.787 158.871 180.775 1.00 115.62 ? 172  LYS A O   1 
ATOM   1171 C CB  . LYS A 1 154  ? 169.374 156.426 180.539 1.00 116.54 ? 172  LYS A CB  1 
ATOM   1172 C CG  . LYS A 1 154  ? 168.358 155.325 180.295 1.00 120.62 ? 172  LYS A CG  1 
ATOM   1173 C CD  . LYS A 1 154  ? 167.899 154.692 181.603 1.00 130.90 ? 172  LYS A CD  1 
ATOM   1174 C CE  . LYS A 1 154  ? 166.783 153.676 181.395 1.00 135.30 ? 172  LYS A CE  1 
ATOM   1175 N NZ  . LYS A 1 154  ? 165.574 154.257 180.748 1.00 139.81 ? 172  LYS A NZ  1 
ATOM   1176 N N   . SER A 1 155  ? 171.478 158.666 178.642 1.00 106.30 ? 173  SER A N   1 
ATOM   1177 C CA  . SER A 1 155  ? 172.507 159.702 178.695 1.00 101.10 ? 173  SER A CA  1 
ATOM   1178 C C   . SER A 1 155  ? 173.624 159.389 179.688 1.00 102.03 ? 173  SER A C   1 
ATOM   1179 O O   . SER A 1 155  ? 174.367 160.292 180.081 1.00 107.27 ? 173  SER A O   1 
ATOM   1180 C CB  . SER A 1 155  ? 171.895 161.070 179.014 1.00 100.46 ? 173  SER A CB  1 
ATOM   1181 O OG  . SER A 1 155  ? 170.813 161.351 178.145 1.00 105.79 ? 173  SER A OG  1 
ATOM   1182 N N   . ASN A 1 156  ? 173.776 158.132 180.102 1.00 100.14 ? 174  ASN A N   1 
ATOM   1183 C CA  . ASN A 1 156  ? 174.948 157.753 180.882 1.00 94.53  ? 174  ASN A CA  1 
ATOM   1184 C C   . ASN A 1 156  ? 176.154 157.643 179.962 1.00 93.93  ? 174  ASN A C   1 
ATOM   1185 O O   . ASN A 1 156  ? 176.117 156.932 178.955 1.00 95.92  ? 174  ASN A O   1 
ATOM   1186 C CB  . ASN A 1 156  ? 174.728 156.426 181.605 1.00 99.79  ? 174  ASN A CB  1 
ATOM   1187 C CG  . ASN A 1 156  ? 173.387 156.346 182.295 1.00 113.01 ? 174  ASN A CG  1 
ATOM   1188 O OD1 . ASN A 1 156  ? 172.442 155.767 181.768 1.00 117.84 ? 174  ASN A OD1 1 
ATOM   1189 N ND2 . ASN A 1 156  ? 173.300 156.919 183.489 1.00 122.76 ? 174  ASN A ND2 1 
ATOM   1190 N N   . LEU A 1 157  ? 177.231 158.335 180.313 1.00 91.71  ? 175  LEU A N   1 
ATOM   1191 C CA  . LEU A 1 157  ? 178.447 158.300 179.508 1.00 86.92  ? 175  LEU A CA  1 
ATOM   1192 C C   . LEU A 1 157  ? 179.076 156.925 179.668 1.00 81.05  ? 175  LEU A C   1 
ATOM   1193 O O   . LEU A 1 157  ? 179.790 156.666 180.639 1.00 87.69  ? 175  LEU A O   1 
ATOM   1194 C CB  . LEU A 1 157  ? 179.401 159.405 179.944 1.00 87.33  ? 175  LEU A CB  1 
ATOM   1195 C CG  . LEU A 1 157  ? 180.786 159.440 179.297 1.00 82.53  ? 175  LEU A CG  1 
ATOM   1196 C CD1 . LEU A 1 157  ? 180.660 159.477 177.787 1.00 83.93  ? 175  LEU A CD1 1 
ATOM   1197 C CD2 . LEU A 1 157  ? 181.571 160.634 179.812 1.00 86.25  ? 175  LEU A CD2 1 
ATOM   1198 N N   . ILE A 1 158  ? 178.825 156.042 178.706 1.00 71.09  ? 176  ILE A N   1 
ATOM   1199 C CA  . ILE A 1 158  ? 179.241 154.649 178.833 1.00 74.57  ? 176  ILE A CA  1 
ATOM   1200 C C   . ILE A 1 158  ? 180.664 154.444 178.332 1.00 79.99  ? 176  ILE A C   1 
ATOM   1201 O O   . ILE A 1 158  ? 181.382 153.588 178.853 1.00 84.64  ? 176  ILE A O   1 
ATOM   1202 C CB  . ILE A 1 158  ? 178.220 153.735 178.113 1.00 74.32  ? 176  ILE A CB  1 
ATOM   1203 C CG1 . ILE A 1 158  ? 177.058 153.462 179.085 1.00 83.41  ? 176  ILE A CG1 1 
ATOM   1204 C CG2 . ILE A 1 158  ? 178.883 152.418 177.572 1.00 73.88  ? 176  ILE A CG2 1 
ATOM   1205 C CD1 . ILE A 1 158  ? 175.968 152.561 178.578 1.00 97.21  ? 176  ILE A CD1 1 
ATOM   1206 N N   . GLN A 1 159  ? 181.097 155.191 177.317 1.00 81.31  ? 177  GLN A N   1 
ATOM   1207 C CA  . GLN A 1 159  ? 182.479 155.105 176.857 1.00 80.55  ? 177  GLN A CA  1 
ATOM   1208 C C   . GLN A 1 159  ? 182.958 156.471 176.401 1.00 86.12  ? 177  GLN A C   1 
ATOM   1209 O O   . GLN A 1 159  ? 182.162 157.313 175.984 1.00 92.47  ? 177  GLN A O   1 
ATOM   1210 C CB  . GLN A 1 159  ? 182.630 154.094 175.715 1.00 78.62  ? 177  GLN A CB  1 
ATOM   1211 C CG  . GLN A 1 159  ? 184.064 153.635 175.469 1.00 82.69  ? 177  GLN A CG  1 
ATOM   1212 C CD  . GLN A 1 159  ? 184.240 152.134 175.595 1.00 90.08  ? 177  GLN A CD  1 
ATOM   1213 O OE1 . GLN A 1 159  ? 183.705 151.505 176.506 1.00 93.26  ? 177  GLN A OE1 1 
ATOM   1214 N NE2 . GLN A 1 159  ? 185.000 151.551 174.674 1.00 82.17  ? 177  GLN A NE2 1 
ATOM   1215 N N   . GLN A 1 160  ? 184.268 156.689 176.486 1.00 80.87  ? 178  GLN A N   1 
ATOM   1216 C CA  . GLN A 1 160  ? 184.825 157.945 176.016 1.00 83.55  ? 178  GLN A CA  1 
ATOM   1217 C C   . GLN A 1 160  ? 186.296 157.794 175.663 1.00 81.29  ? 178  GLN A C   1 
ATOM   1218 O O   . GLN A 1 160  ? 187.009 156.958 176.223 1.00 82.42  ? 178  GLN A O   1 
ATOM   1219 C CB  . GLN A 1 160  ? 184.637 159.065 177.052 1.00 85.97  ? 178  GLN A CB  1 
ATOM   1220 C CG  . GLN A 1 160  ? 185.331 158.873 178.403 1.00 86.20  ? 178  GLN A CG  1 
ATOM   1221 C CD  . GLN A 1 160  ? 185.595 160.191 179.102 1.00 92.02  ? 178  GLN A CD  1 
ATOM   1222 O OE1 . GLN A 1 160  ? 184.893 161.176 178.879 1.00 88.58  ? 178  GLN A OE1 1 
ATOM   1223 N NE2 . GLN A 1 160  ? 186.616 160.218 179.949 1.00 97.43  ? 178  GLN A NE2 1 
ATOM   1224 N N   . TRP A 1 161  ? 186.727 158.624 174.717 1.00 83.51  ? 179  TRP A N   1 
ATOM   1225 C CA  . TRP A 1 161  ? 188.130 158.849 174.406 1.00 83.75  ? 179  TRP A CA  1 
ATOM   1226 C C   . TRP A 1 161  ? 188.385 160.343 174.501 1.00 86.96  ? 179  TRP A C   1 
ATOM   1227 O O   . TRP A 1 161  ? 187.557 161.142 174.056 1.00 92.59  ? 179  TRP A O   1 
ATOM   1228 C CB  . TRP A 1 161  ? 188.493 158.350 173.007 1.00 85.31  ? 179  TRP A CB  1 
ATOM   1229 C CG  . TRP A 1 161  ? 188.306 156.884 172.817 1.00 85.47  ? 179  TRP A CG  1 
ATOM   1230 C CD1 . TRP A 1 161  ? 189.259 155.917 172.918 1.00 87.31  ? 179  TRP A CD1 1 
ATOM   1231 C CD2 . TRP A 1 161  ? 187.088 156.215 172.483 1.00 84.81  ? 179  TRP A CD2 1 
ATOM   1232 N NE1 . TRP A 1 161  ? 188.710 154.685 172.671 1.00 88.60  ? 179  TRP A NE1 1 
ATOM   1233 C CE2 . TRP A 1 161  ? 187.377 154.841 172.400 1.00 89.92  ? 179  TRP A CE2 1 
ATOM   1234 C CE3 . TRP A 1 161  ? 185.781 156.644 172.247 1.00 85.19  ? 179  TRP A CE3 1 
ATOM   1235 C CZ2 . TRP A 1 161  ? 186.407 153.894 172.095 1.00 94.87  ? 179  TRP A CZ2 1 
ATOM   1236 C CZ3 . TRP A 1 161  ? 184.822 155.704 171.944 1.00 84.62  ? 179  TRP A CZ3 1 
ATOM   1237 C CH2 . TRP A 1 161  ? 185.138 154.345 171.869 1.00 87.90  ? 179  TRP A CH2 1 
ATOM   1238 N N   . LEU A 1 162  ? 189.524 160.718 175.077 1.00 86.99  ? 180  LEU A N   1 
ATOM   1239 C CA  . LEU A 1 162  ? 189.845 162.110 175.359 1.00 93.47  ? 180  LEU A CA  1 
ATOM   1240 C C   . LEU A 1 162  ? 191.124 162.514 174.643 1.00 101.54 ? 180  LEU A C   1 
ATOM   1241 O O   . LEU A 1 162  ? 192.119 161.784 174.665 1.00 103.93 ? 180  LEU A O   1 
ATOM   1242 C CB  . LEU A 1 162  ? 190.001 162.343 176.867 1.00 92.15  ? 180  LEU A CB  1 
ATOM   1243 C CG  . LEU A 1 162  ? 188.785 162.123 177.777 1.00 91.68  ? 180  LEU A CG  1 
ATOM   1244 C CD1 . LEU A 1 162  ? 189.064 162.717 179.144 1.00 102.46 ? 180  LEU A CD1 1 
ATOM   1245 C CD2 . LEU A 1 162  ? 187.494 162.703 177.212 1.00 91.26  ? 180  LEU A CD2 1 
ATOM   1246 N N   . SER A 1 163  ? 191.084 163.693 174.018 1.00 99.18  ? 181  SER A N   1 
ATOM   1247 C CA  . SER A 1 163  ? 192.248 164.298 173.372 1.00 102.55 ? 181  SER A CA  1 
ATOM   1248 C C   . SER A 1 163  ? 192.830 163.392 172.289 1.00 105.61 ? 181  SER A C   1 
ATOM   1249 O O   . SER A 1 163  ? 194.048 163.297 172.123 1.00 111.06 ? 181  SER A O   1 
ATOM   1250 C CB  . SER A 1 163  ? 193.317 164.662 174.404 1.00 103.46 ? 181  SER A CB  1 
ATOM   1251 O OG  . SER A 1 163  ? 192.821 165.614 175.327 1.00 105.02 ? 181  SER A OG  1 
ATOM   1252 N N   . GLN A 1 164  ? 191.958 162.720 171.545 1.00 98.70  ? 182  GLN A N   1 
ATOM   1253 C CA  . GLN A 1 164  ? 192.410 161.958 170.392 1.00 97.89  ? 182  GLN A CA  1 
ATOM   1254 C C   . GLN A 1 164  ? 192.915 162.904 169.309 1.00 101.00 ? 182  GLN A C   1 
ATOM   1255 O O   . GLN A 1 164  ? 192.404 164.014 169.138 1.00 101.97 ? 182  GLN A O   1 
ATOM   1256 C CB  . GLN A 1 164  ? 191.281 161.086 169.843 1.00 91.22  ? 182  GLN A CB  1 
ATOM   1257 C CG  . GLN A 1 164  ? 190.763 160.040 170.811 1.00 91.09  ? 182  GLN A CG  1 
ATOM   1258 C CD  . GLN A 1 164  ? 191.784 158.963 171.104 1.00 100.17 ? 182  GLN A CD  1 
ATOM   1259 O OE1 . GLN A 1 164  ? 192.011 158.071 170.288 1.00 103.24 ? 182  GLN A OE1 1 
ATOM   1260 N NE2 . GLN A 1 164  ? 192.411 159.041 172.272 1.00 101.76 ? 182  GLN A NE2 1 
ATOM   1261 N N   . GLN A 1 165  ? 193.938 162.459 168.584 1.00 103.94 ? 183  GLN A N   1 
ATOM   1262 C CA  . GLN A 1 165  ? 194.560 163.244 167.526 1.00 107.99 ? 183  GLN A CA  1 
ATOM   1263 C C   . GLN A 1 165  ? 194.067 162.758 166.171 1.00 107.07 ? 183  GLN A C   1 
ATOM   1264 O O   . GLN A 1 165  ? 194.092 161.555 165.890 1.00 111.10 ? 183  GLN A O   1 
ATOM   1265 C CB  . GLN A 1 165  ? 196.084 163.146 167.598 1.00 112.69 ? 183  GLN A CB  1 
ATOM   1266 C CG  . GLN A 1 165  ? 196.762 164.439 168.024 1.00 120.93 ? 183  GLN A CG  1 
ATOM   1267 C CD  . GLN A 1 165  ? 196.720 165.507 166.947 1.00 127.93 ? 183  GLN A CD  1 
ATOM   1268 O OE1 . GLN A 1 165  ? 196.533 165.211 165.767 1.00 127.72 ? 183  GLN A OE1 1 
ATOM   1269 N NE2 . GLN A 1 165  ? 196.893 166.760 167.351 1.00 120.93 ? 183  GLN A NE2 1 
ATOM   1270 N N   . SER A 1 166  ? 193.626 163.695 165.336 1.00 106.97 ? 184  SER A N   1 
ATOM   1271 C CA  . SER A 1 166  ? 193.099 163.383 164.009 1.00 108.40 ? 184  SER A CA  1 
ATOM   1272 C C   . SER A 1 166  ? 194.258 163.335 163.023 1.00 110.52 ? 184  SER A C   1 
ATOM   1273 O O   . SER A 1 166  ? 194.823 164.370 162.660 1.00 108.17 ? 184  SER A O   1 
ATOM   1274 C CB  . SER A 1 166  ? 192.058 164.415 163.589 1.00 104.49 ? 184  SER A CB  1 
ATOM   1275 O OG  . SER A 1 166  ? 192.398 165.702 164.065 1.00 109.48 ? 184  SER A OG  1 
ATOM   1276 N N   . ASP A 1 167  ? 194.613 162.129 162.588 1.00 117.93 ? 185  ASP A N   1 
ATOM   1277 C CA  . ASP A 1 167  ? 195.624 161.951 161.544 1.00 119.30 ? 185  ASP A CA  1 
ATOM   1278 C C   . ASP A 1 167  ? 194.928 162.107 160.197 1.00 113.37 ? 185  ASP A C   1 
ATOM   1279 O O   . ASP A 1 167  ? 194.229 161.205 159.731 1.00 115.30 ? 185  ASP A O   1 
ATOM   1280 C CB  . ASP A 1 167  ? 196.334 160.602 161.664 1.00 129.11 ? 185  ASP A CB  1 
ATOM   1281 C CG  . ASP A 1 167  ? 195.377 159.423 161.760 1.00 139.04 ? 185  ASP A CG  1 
ATOM   1282 O OD1 . ASP A 1 167  ? 194.432 159.489 162.573 1.00 139.87 ? 185  ASP A OD1 1 
ATOM   1283 O OD2 . ASP A 1 167  ? 195.571 158.435 161.021 1.00 139.55 ? 185  ASP A OD2 1 
ATOM   1284 N N   . LEU A 1 168  ? 195.120 163.268 159.570 1.00 105.93 ? 186  LEU A N   1 
ATOM   1285 C CA  . LEU A 1 168  ? 194.452 163.621 158.314 1.00 99.07  ? 186  LEU A CA  1 
ATOM   1286 C C   . LEU A 1 168  ? 192.930 163.527 158.455 1.00 102.19 ? 186  LEU A C   1 
ATOM   1287 O O   . LEU A 1 168  ? 192.219 163.115 157.537 1.00 104.68 ? 186  LEU A O   1 
ATOM   1288 C CB  . LEU A 1 168  ? 194.964 162.756 157.153 1.00 88.03  ? 186  LEU A CB  1 
ATOM   1289 C CG  . LEU A 1 168  ? 196.326 163.168 156.586 1.00 92.17  ? 186  LEU A CG  1 
ATOM   1290 C CD1 . LEU A 1 168  ? 197.457 162.473 157.327 1.00 103.92 ? 186  LEU A CD1 1 
ATOM   1291 C CD2 . LEU A 1 168  ? 196.398 162.869 155.099 1.00 94.14  ? 186  LEU A CD2 1 
ATOM   1292 N N   . GLY A 1 169  ? 192.422 163.912 159.626 1.00 100.09 ? 187  GLY A N   1 
ATOM   1293 C CA  . GLY A 1 169  ? 191.000 164.074 159.835 1.00 94.10  ? 187  GLY A CA  1 
ATOM   1294 C C   . GLY A 1 169  ? 190.226 162.818 160.171 1.00 93.69  ? 187  GLY A C   1 
ATOM   1295 O O   . GLY A 1 169  ? 189.157 162.924 160.785 1.00 98.53  ? 187  GLY A O   1 
ATOM   1296 N N   . VAL A 1 170  ? 190.720 161.638 159.811 1.00 92.10  ? 188  VAL A N   1 
ATOM   1297 C CA  . VAL A 1 170  ? 189.985 160.388 159.981 1.00 86.00  ? 188  VAL A CA  1 
ATOM   1298 C C   . VAL A 1 170  ? 190.418 159.749 161.291 1.00 96.12  ? 188  VAL A C   1 
ATOM   1299 O O   . VAL A 1 170  ? 191.616 159.564 161.535 1.00 105.22 ? 188  VAL A O   1 
ATOM   1300 C CB  . VAL A 1 170  ? 190.221 159.430 158.803 1.00 87.70  ? 188  VAL A CB  1 
ATOM   1301 C CG1 . VAL A 1 170  ? 189.478 158.117 159.031 1.00 91.14  ? 188  VAL A CG1 1 
ATOM   1302 C CG2 . VAL A 1 170  ? 189.791 160.076 157.496 1.00 92.70  ? 188  VAL A CG2 1 
ATOM   1303 N N   . ILE A 1 171  ? 189.443 159.417 162.135 1.00 89.94  ? 189  ILE A N   1 
ATOM   1304 C CA  . ILE A 1 171  ? 189.664 158.670 163.371 1.00 86.28  ? 189  ILE A CA  1 
ATOM   1305 C C   . ILE A 1 171  ? 188.724 157.476 163.342 1.00 90.53  ? 189  ILE A C   1 
ATOM   1306 O O   . ILE A 1 171  ? 187.514 157.635 163.532 1.00 93.79  ? 189  ILE A O   1 
ATOM   1307 C CB  . ILE A 1 171  ? 189.418 159.526 164.621 1.00 83.36  ? 189  ILE A CB  1 
ATOM   1308 C CG1 . ILE A 1 171  ? 190.447 160.659 164.722 1.00 94.97  ? 189  ILE A CG1 1 
ATOM   1309 C CG2 . ILE A 1 171  ? 189.424 158.662 165.881 1.00 83.38  ? 189  ILE A CG2 1 
ATOM   1310 C CD1 . ILE A 1 171  ? 189.835 161.998 165.051 1.00 98.16  ? 189  ILE A CD1 1 
ATOM   1311 N N   . SER A 1 172  ? 189.272 156.286 163.114 1.00 92.34  ? 190  SER A N   1 
ATOM   1312 C CA  . SER A 1 172  ? 188.498 155.050 163.094 1.00 92.34  ? 190  SER A CA  1 
ATOM   1313 C C   . SER A 1 172  ? 188.556 154.414 164.476 1.00 91.87  ? 190  SER A C   1 
ATOM   1314 O O   . SER A 1 172  ? 189.645 154.213 165.023 1.00 91.72  ? 190  SER A O   1 
ATOM   1315 C CB  . SER A 1 172  ? 189.035 154.085 162.039 1.00 96.60  ? 190  SER A CB  1 
ATOM   1316 O OG  . SER A 1 172  ? 188.479 152.794 162.206 1.00 99.99  ? 190  SER A OG  1 
ATOM   1317 N N   . LYS A 1 173  ? 187.388 154.102 165.035 1.00 89.29  ? 191  LYS A N   1 
ATOM   1318 C CA  . LYS A 1 173  ? 187.274 153.553 166.376 1.00 84.82  ? 191  LYS A CA  1 
ATOM   1319 C C   . LYS A 1 173  ? 186.205 152.471 166.396 1.00 90.31  ? 191  LYS A C   1 
ATOM   1320 O O   . LYS A 1 173  ? 185.395 152.347 165.471 1.00 96.96  ? 191  LYS A O   1 
ATOM   1321 C CB  . LYS A 1 173  ? 186.925 154.641 167.399 1.00 81.01  ? 191  LYS A CB  1 
ATOM   1322 C CG  . LYS A 1 173  ? 187.990 155.707 167.597 1.00 85.00  ? 191  LYS A CG  1 
ATOM   1323 C CD  . LYS A 1 173  ? 189.218 155.168 168.305 1.00 89.56  ? 191  LYS A CD  1 
ATOM   1324 C CE  . LYS A 1 173  ? 190.147 156.296 168.717 1.00 89.89  ? 191  LYS A CE  1 
ATOM   1325 N NZ  . LYS A 1 173  ? 191.466 155.799 169.192 1.00 96.48  ? 191  LYS A NZ  1 
ATOM   1326 N N   . THR A 1 174  ? 186.219 151.687 167.473 1.00 87.27  ? 192  THR A N   1 
ATOM   1327 C CA  . THR A 1 174  ? 185.253 150.624 167.700 1.00 86.60  ? 192  THR A CA  1 
ATOM   1328 C C   . THR A 1 174  ? 184.737 150.706 169.128 1.00 89.52  ? 192  THR A C   1 
ATOM   1329 O O   . THR A 1 174  ? 185.398 151.241 170.021 1.00 91.59  ? 192  THR A O   1 
ATOM   1330 C CB  . THR A 1 174  ? 185.864 149.241 167.454 1.00 88.15  ? 192  THR A CB  1 
ATOM   1331 O OG1 . THR A 1 174  ? 187.085 149.117 168.192 1.00 89.03  ? 192  THR A OG1 1 
ATOM   1332 C CG2 . THR A 1 174  ? 186.144 149.035 165.976 1.00 93.14  ? 192  THR A CG2 1 
ATOM   1333 N N   . PHE A 1 175  ? 183.538 150.167 169.328 1.00 89.23  ? 193  PHE A N   1 
ATOM   1334 C CA  . PHE A 1 175  ? 182.888 150.168 170.635 1.00 84.26  ? 193  PHE A CA  1 
ATOM   1335 C C   . PHE A 1 175  ? 182.090 148.882 170.767 1.00 90.59  ? 193  PHE A C   1 
ATOM   1336 O O   . PHE A 1 175  ? 181.179 148.637 169.972 1.00 94.99  ? 193  PHE A O   1 
ATOM   1337 C CB  . PHE A 1 175  ? 181.982 151.389 170.789 1.00 73.70  ? 193  PHE A CB  1 
ATOM   1338 C CG  . PHE A 1 175  ? 181.031 151.298 171.944 1.00 77.48  ? 193  PHE A CG  1 
ATOM   1339 C CD1 . PHE A 1 175  ? 181.495 151.102 173.230 1.00 84.90  ? 193  PHE A CD1 1 
ATOM   1340 C CD2 . PHE A 1 175  ? 179.669 151.413 171.742 1.00 79.91  ? 193  PHE A CD2 1 
ATOM   1341 C CE1 . PHE A 1 175  ? 180.618 151.020 174.292 1.00 86.91  ? 193  PHE A CE1 1 
ATOM   1342 C CE2 . PHE A 1 175  ? 178.789 151.333 172.800 1.00 77.85  ? 193  PHE A CE2 1 
ATOM   1343 C CZ  . PHE A 1 175  ? 179.264 151.136 174.075 1.00 79.63  ? 193  PHE A CZ  1 
ATOM   1344 N N   . GLN A 1 176  ? 182.426 148.065 171.759 1.00 87.47  ? 194  GLN A N   1 
ATOM   1345 C CA  . GLN A 1 176  ? 181.786 146.768 171.941 1.00 87.02  ? 194  GLN A CA  1 
ATOM   1346 C C   . GLN A 1 176  ? 180.560 146.931 172.829 1.00 87.31  ? 194  GLN A C   1 
ATOM   1347 O O   . GLN A 1 176  ? 180.676 147.352 173.984 1.00 92.42  ? 194  GLN A O   1 
ATOM   1348 C CB  . GLN A 1 176  ? 182.759 145.761 172.550 1.00 93.25  ? 194  GLN A CB  1 
ATOM   1349 C CG  . GLN A 1 176  ? 183.091 144.599 171.632 1.00 96.33  ? 194  GLN A CG  1 
ATOM   1350 C CD  . GLN A 1 176  ? 181.959 143.597 171.532 1.00 102.44 ? 194  GLN A CD  1 
ATOM   1351 O OE1 . GLN A 1 176  ? 180.888 143.795 172.104 1.00 100.93 ? 194  GLN A OE1 1 
ATOM   1352 N NE2 . GLN A 1 176  ? 182.191 142.513 170.803 1.00 107.96 ? 194  GLN A NE2 1 
ATOM   1353 N N   . LEU A 1 177  ? 179.390 146.599 172.290 1.00 86.05  ? 195  LEU A N   1 
ATOM   1354 C CA  . LEU A 1 177  ? 178.162 146.692 173.062 1.00 90.37  ? 195  LEU A CA  1 
ATOM   1355 C C   . LEU A 1 177  ? 178.088 145.566 174.089 1.00 102.94 ? 195  LEU A C   1 
ATOM   1356 O O   . LEU A 1 177  ? 178.645 144.481 173.907 1.00 106.17 ? 195  LEU A O   1 
ATOM   1357 C CB  . LEU A 1 177  ? 176.941 146.638 172.146 1.00 86.77  ? 195  LEU A CB  1 
ATOM   1358 C CG  . LEU A 1 177  ? 176.702 147.879 171.287 1.00 78.10  ? 195  LEU A CG  1 
ATOM   1359 C CD1 . LEU A 1 177  ? 176.105 147.501 169.947 1.00 85.85  ? 195  LEU A CD1 1 
ATOM   1360 C CD2 . LEU A 1 177  ? 175.801 148.856 172.009 1.00 78.90  ? 195  LEU A CD2 1 
ATOM   1361 N N   . SER A 1 178  ? 177.382 145.839 175.181 1.00 104.85 ? 196  SER A N   1 
ATOM   1362 C CA  . SER A 1 178  ? 177.221 144.860 176.241 1.00 106.43 ? 196  SER A CA  1 
ATOM   1363 C C   . SER A 1 178  ? 176.233 143.776 175.821 1.00 108.34 ? 196  SER A C   1 
ATOM   1364 O O   . SER A 1 178  ? 175.545 143.879 174.803 1.00 110.53 ? 196  SER A O   1 
ATOM   1365 C CB  . SER A 1 178  ? 176.748 145.538 177.525 1.00 108.20 ? 196  SER A CB  1 
ATOM   1366 O OG  . SER A 1 178  ? 175.337 145.663 177.540 1.00 109.00 ? 196  SER A OG  1 
ATOM   1367 N N   . SER A 1 179  ? 176.174 142.714 176.625 1.00 108.72 ? 197  SER A N   1 
ATOM   1368 C CA  . SER A 1 179  ? 175.254 141.620 176.336 1.00 109.66 ? 197  SER A CA  1 
ATOM   1369 C C   . SER A 1 179  ? 173.803 142.067 176.464 1.00 110.79 ? 197  SER A C   1 
ATOM   1370 O O   . SER A 1 179  ? 172.953 141.663 175.664 1.00 114.60 ? 197  SER A O   1 
ATOM   1371 C CB  . SER A 1 179  ? 175.531 140.444 177.271 1.00 112.95 ? 197  SER A CB  1 
ATOM   1372 O OG  . SER A 1 179  ? 175.132 140.747 178.595 1.00 118.44 ? 197  SER A OG  1 
ATOM   1373 N N   . HIS A 1 180  ? 173.504 142.899 177.464 1.00 103.87 ? 198  HIS A N   1 
ATOM   1374 C CA  . HIS A 1 180  ? 172.144 143.348 177.768 1.00 100.95 ? 198  HIS A CA  1 
ATOM   1375 C C   . HIS A 1 180  ? 172.156 144.863 177.925 1.00 101.52 ? 198  HIS A C   1 
ATOM   1376 O O   . HIS A 1 180  ? 172.066 145.383 179.044 1.00 103.48 ? 198  HIS A O   1 
ATOM   1377 C CB  . HIS A 1 180  ? 171.617 142.664 179.028 1.00 102.33 ? 198  HIS A CB  1 
ATOM   1378 C CG  . HIS A 1 180  ? 171.616 141.170 178.943 1.00 110.80 ? 198  HIS A CG  1 
ATOM   1379 N ND1 . HIS A 1 180  ? 172.740 140.411 179.187 1.00 114.35 ? 198  HIS A ND1 1 
ATOM   1380 C CD2 . HIS A 1 180  ? 170.631 140.295 178.633 1.00 118.63 ? 198  HIS A CD2 1 
ATOM   1381 C CE1 . HIS A 1 180  ? 172.446 139.132 179.035 1.00 120.52 ? 198  HIS A CE1 1 
ATOM   1382 N NE2 . HIS A 1 180  ? 171.172 139.035 178.699 1.00 124.32 ? 198  HIS A NE2 1 
ATOM   1383 N N   . PRO A 1 181  ? 172.268 145.606 176.818 1.00 98.69  ? 199  PRO A N   1 
ATOM   1384 C CA  . PRO A 1 181  ? 172.308 147.070 176.913 1.00 96.78  ? 199  PRO A CA  1 
ATOM   1385 C C   . PRO A 1 181  ? 170.930 147.701 177.000 1.00 100.23 ? 199  PRO A C   1 
ATOM   1386 O O   . PRO A 1 181  ? 169.914 147.002 176.939 1.00 105.54 ? 199  PRO A O   1 
ATOM   1387 C CB  . PRO A 1 181  ? 173.021 147.469 175.619 1.00 96.80  ? 199  PRO A CB  1 
ATOM   1388 C CG  . PRO A 1 181  ? 172.625 146.423 174.648 1.00 97.33  ? 199  PRO A CG  1 
ATOM   1389 C CD  . PRO A 1 181  ? 172.386 145.153 175.422 1.00 98.10  ? 199  PRO A CD  1 
ATOM   1390 N N   . ILE A 1 182  ? 170.887 149.024 177.139 1.00 98.94  ? 200  ILE A N   1 
ATOM   1391 C CA  . ILE A 1 182  ? 169.629 149.763 177.146 1.00 101.79 ? 200  ILE A CA  1 
ATOM   1392 C C   . ILE A 1 182  ? 169.215 149.979 175.695 1.00 105.45 ? 200  ILE A C   1 
ATOM   1393 O O   . ILE A 1 182  ? 169.843 150.750 174.967 1.00 105.99 ? 200  ILE A O   1 
ATOM   1394 C CB  . ILE A 1 182  ? 169.761 151.095 177.895 1.00 99.84  ? 200  ILE A CB  1 
ATOM   1395 C CG1 . ILE A 1 182  ? 170.137 150.839 179.360 1.00 97.13  ? 200  ILE A CG1 1 
ATOM   1396 C CG2 . ILE A 1 182  ? 168.469 151.921 177.777 1.00 98.54  ? 200  ILE A CG2 1 
ATOM   1397 C CD1 . ILE A 1 182  ? 171.509 151.344 179.723 1.00 98.88  ? 200  ILE A CD1 1 
ATOM   1398 N N   . LEU A 1 183  ? 168.152 149.301 175.277 1.00 105.48 ? 201  LEU A N   1 
ATOM   1399 C CA  . LEU A 1 183  ? 167.678 149.393 173.904 1.00 98.23  ? 201  LEU A CA  1 
ATOM   1400 C C   . LEU A 1 183  ? 167.097 150.774 173.642 1.00 98.37  ? 201  LEU A C   1 
ATOM   1401 O O   . LEU A 1 183  ? 166.375 151.325 174.478 1.00 103.47 ? 201  LEU A O   1 
ATOM   1402 C CB  . LEU A 1 183  ? 166.621 148.322 173.639 1.00 93.36  ? 201  LEU A CB  1 
ATOM   1403 C CG  . LEU A 1 183  ? 167.122 146.931 173.239 1.00 98.51  ? 201  LEU A CG  1 
ATOM   1404 C CD1 . LEU A 1 183  ? 168.079 146.342 174.273 1.00 96.23  ? 201  LEU A CD1 1 
ATOM   1405 C CD2 . LEU A 1 183  ? 165.937 145.998 173.002 1.00 110.47 ? 201  LEU A CD2 1 
ATOM   1406 N N   . GLY A 1 184  ? 167.408 151.330 172.476 1.00 94.00  ? 202  GLY A N   1 
ATOM   1407 C CA  . GLY A 1 184  ? 166.960 152.656 172.113 1.00 95.02  ? 202  GLY A CA  1 
ATOM   1408 C C   . GLY A 1 184  ? 168.003 153.360 171.275 1.00 100.37 ? 202  GLY A C   1 
ATOM   1409 O O   . GLY A 1 184  ? 168.867 152.727 170.676 1.00 102.45 ? 202  GLY A O   1 
ATOM   1410 N N   . ASP A 1 185  ? 167.918 154.687 171.244 1.00 99.69  ? 203  ASP A N   1 
ATOM   1411 C CA  . ASP A 1 185  ? 168.762 155.507 170.377 1.00 99.95  ? 203  ASP A CA  1 
ATOM   1412 C C   . ASP A 1 185  ? 170.017 155.914 171.138 1.00 96.55  ? 203  ASP A C   1 
ATOM   1413 O O   . ASP A 1 185  ? 170.042 156.947 171.810 1.00 97.86  ? 203  ASP A O   1 
ATOM   1414 C CB  . ASP A 1 185  ? 167.997 156.731 169.889 1.00 106.62 ? 203  ASP A CB  1 
ATOM   1415 C CG  . ASP A 1 185  ? 166.981 156.398 168.811 1.00 128.10 ? 203  ASP A CG  1 
ATOM   1416 O OD1 . ASP A 1 185  ? 167.301 155.598 167.907 1.00 125.50 ? 203  ASP A OD1 1 
ATOM   1417 O OD2 . ASP A 1 185  ? 165.858 156.939 168.869 1.00 148.80 ? 203  ASP A OD2 1 
ATOM   1418 N N   . TRP A 1 186  ? 171.068 155.106 171.026 1.00 89.85  ? 204  TRP A N   1 
ATOM   1419 C CA  . TRP A 1 186  ? 172.363 155.496 171.553 1.00 85.33  ? 204  TRP A CA  1 
ATOM   1420 C C   . TRP A 1 186  ? 172.879 156.706 170.787 1.00 85.55  ? 204  TRP A C   1 
ATOM   1421 O O   . TRP A 1 186  ? 172.476 156.959 169.650 1.00 93.86  ? 204  TRP A O   1 
ATOM   1422 C CB  . TRP A 1 186  ? 173.363 154.353 171.422 1.00 79.69  ? 204  TRP A CB  1 
ATOM   1423 C CG  . TRP A 1 186  ? 173.133 153.216 172.351 1.00 85.06  ? 204  TRP A CG  1 
ATOM   1424 C CD1 . TRP A 1 186  ? 172.017 152.442 172.445 1.00 86.07  ? 204  TRP A CD1 1 
ATOM   1425 C CD2 . TRP A 1 186  ? 174.053 152.715 173.321 1.00 89.79  ? 204  TRP A CD2 1 
ATOM   1426 N NE1 . TRP A 1 186  ? 172.183 151.492 173.420 1.00 87.88  ? 204  TRP A NE1 1 
ATOM   1427 C CE2 . TRP A 1 186  ? 173.428 151.639 173.972 1.00 90.09  ? 204  TRP A CE2 1 
ATOM   1428 C CE3 . TRP A 1 186  ? 175.348 153.074 173.703 1.00 90.85  ? 204  TRP A CE3 1 
ATOM   1429 C CZ2 . TRP A 1 186  ? 174.052 150.919 174.981 1.00 94.70  ? 204  TRP A CZ2 1 
ATOM   1430 C CZ3 . TRP A 1 186  ? 175.963 152.359 174.704 1.00 86.71  ? 204  TRP A CZ3 1 
ATOM   1431 C CH2 . TRP A 1 186  ? 175.317 151.292 175.330 1.00 89.51  ? 204  TRP A CH2 1 
ATOM   1432 N N   . SER A 1 187  ? 173.795 157.449 171.413 1.00 82.67  ? 205  SER A N   1 
ATOM   1433 C CA  . SER A 1 187  ? 174.321 158.680 170.838 1.00 80.83  ? 205  SER A CA  1 
ATOM   1434 C C   . SER A 1 187  ? 175.840 158.689 170.885 1.00 83.84  ? 205  SER A C   1 
ATOM   1435 O O   . SER A 1 187  ? 176.447 158.243 171.863 1.00 89.65  ? 205  SER A O   1 
ATOM   1436 C CB  . SER A 1 187  ? 173.780 159.904 171.576 1.00 86.90  ? 205  SER A CB  1 
ATOM   1437 O OG  . SER A 1 187  ? 174.670 160.308 172.598 1.00 101.48 ? 205  SER A OG  1 
ATOM   1438 N N   . ILE A 1 188  ? 176.442 159.191 169.809 1.00 79.86  ? 206  ILE A N   1 
ATOM   1439 C CA  . ILE A 1 188  ? 177.867 159.486 169.731 1.00 77.65  ? 206  ILE A CA  1 
ATOM   1440 C C   . ILE A 1 188  ? 177.996 160.997 169.654 1.00 81.63  ? 206  ILE A C   1 
ATOM   1441 O O   . ILE A 1 188  ? 177.498 161.617 168.706 1.00 92.51  ? 206  ILE A O   1 
ATOM   1442 C CB  . ILE A 1 188  ? 178.525 158.820 168.512 1.00 70.11  ? 206  ILE A CB  1 
ATOM   1443 C CG1 . ILE A 1 188  ? 178.549 157.300 168.664 1.00 76.13  ? 206  ILE A CG1 1 
ATOM   1444 C CG2 . ILE A 1 188  ? 179.939 159.345 168.308 1.00 70.84  ? 206  ILE A CG2 1 
ATOM   1445 C CD1 . ILE A 1 188  ? 178.565 156.567 167.343 1.00 79.87  ? 206  ILE A CD1 1 
ATOM   1446 N N   . GLN A 1 189  ? 178.651 161.588 170.648 1.00 78.09  ? 207  GLN A N   1 
ATOM   1447 C CA  . GLN A 1 189  ? 178.887 163.022 170.720 1.00 82.65  ? 207  GLN A CA  1 
ATOM   1448 C C   . GLN A 1 189  ? 180.379 163.269 170.570 1.00 82.32  ? 207  GLN A C   1 
ATOM   1449 O O   . GLN A 1 189  ? 181.181 162.736 171.344 1.00 86.30  ? 207  GLN A O   1 
ATOM   1450 C CB  . GLN A 1 189  ? 178.374 163.596 172.039 1.00 86.40  ? 207  GLN A CB  1 
ATOM   1451 C CG  . GLN A 1 189  ? 177.022 163.050 172.463 1.00 94.14  ? 207  GLN A CG  1 
ATOM   1452 C CD  . GLN A 1 189  ? 176.391 163.855 173.580 1.00 111.24 ? 207  GLN A CD  1 
ATOM   1453 O OE1 . GLN A 1 189  ? 176.954 164.849 174.040 1.00 119.36 ? 207  GLN A OE1 1 
ATOM   1454 N NE2 . GLN A 1 189  ? 175.213 163.433 174.020 1.00 108.12 ? 207  GLN A NE2 1 
ATOM   1455 N N   . VAL A 1 190  ? 180.743 164.073 169.578 1.00 82.95  ? 208  VAL A N   1 
ATOM   1456 C CA  . VAL A 1 190  ? 182.127 164.427 169.292 1.00 79.18  ? 208  VAL A CA  1 
ATOM   1457 C C   . VAL A 1 190  ? 182.297 165.895 169.646 1.00 90.78  ? 208  VAL A C   1 
ATOM   1458 O O   . VAL A 1 190  ? 181.604 166.757 169.092 1.00 100.09 ? 208  VAL A O   1 
ATOM   1459 C CB  . VAL A 1 190  ? 182.481 164.158 167.823 1.00 78.01  ? 208  VAL A CB  1 
ATOM   1460 C CG1 . VAL A 1 190  ? 183.803 164.809 167.456 1.00 81.19  ? 208  VAL A CG1 1 
ATOM   1461 C CG2 . VAL A 1 190  ? 182.525 162.661 167.563 1.00 81.08  ? 208  VAL A CG2 1 
ATOM   1462 N N   . GLN A 1 191  ? 183.209 166.174 170.572 1.00 90.60  ? 209  GLN A N   1 
ATOM   1463 C CA  . GLN A 1 191  ? 183.507 167.528 171.021 1.00 92.63  ? 209  GLN A CA  1 
ATOM   1464 C C   . GLN A 1 191  ? 184.810 167.970 170.370 1.00 95.44  ? 209  GLN A C   1 
ATOM   1465 O O   . GLN A 1 191  ? 185.860 167.359 170.597 1.00 101.76 ? 209  GLN A O   1 
ATOM   1466 C CB  . GLN A 1 191  ? 183.610 167.583 172.542 1.00 89.91  ? 209  GLN A CB  1 
ATOM   1467 C CG  . GLN A 1 191  ? 182.344 167.155 173.255 1.00 92.80  ? 209  GLN A CG  1 
ATOM   1468 C CD  . GLN A 1 191  ? 182.446 167.311 174.755 1.00 102.63 ? 209  GLN A CD  1 
ATOM   1469 O OE1 . GLN A 1 191  ? 183.461 167.772 175.275 1.00 103.19 ? 209  GLN A OE1 1 
ATOM   1470 N NE2 . GLN A 1 191  ? 181.391 166.927 175.461 1.00 105.32 ? 209  GLN A NE2 1 
ATOM   1471 N N   . VAL A 1 192  ? 184.736 169.026 169.560 1.00 97.59  ? 210  VAL A N   1 
ATOM   1472 C CA  . VAL A 1 192  ? 185.896 169.619 168.902 1.00 102.23 ? 210  VAL A CA  1 
ATOM   1473 C C   . VAL A 1 192  ? 185.958 171.085 169.294 1.00 113.23 ? 210  VAL A C   1 
ATOM   1474 O O   . VAL A 1 192  ? 184.953 171.798 169.216 1.00 119.90 ? 210  VAL A O   1 
ATOM   1475 C CB  . VAL A 1 192  ? 185.854 169.467 167.363 1.00 101.87 ? 210  VAL A CB  1 
ATOM   1476 C CG1 . VAL A 1 192  ? 185.781 168.002 166.957 1.00 94.85  ? 210  VAL A CG1 1 
ATOM   1477 C CG2 . VAL A 1 192  ? 184.695 170.253 166.755 1.00 109.94 ? 210  VAL A CG2 1 
ATOM   1478 N N   . ASN A 1 193  ? 187.139 171.530 169.725 1.00 117.84 ? 211  ASN A N   1 
ATOM   1479 C CA  . ASN A 1 193  ? 187.326 172.908 170.164 1.00 131.60 ? 211  ASN A CA  1 
ATOM   1480 C C   . ASN A 1 193  ? 186.376 173.214 171.321 1.00 137.36 ? 211  ASN A C   1 
ATOM   1481 O O   . ASN A 1 193  ? 186.743 173.014 172.484 1.00 139.82 ? 211  ASN A O   1 
ATOM   1482 C CB  . ASN A 1 193  ? 187.149 173.868 168.979 1.00 139.17 ? 211  ASN A CB  1 
ATOM   1483 C CG  . ASN A 1 193  ? 187.461 175.305 169.339 1.00 148.88 ? 211  ASN A CG  1 
ATOM   1484 O OD1 . ASN A 1 193  ? 186.710 175.951 170.071 1.00 150.16 ? 211  ASN A OD1 1 
ATOM   1485 N ND2 . ASN A 1 193  ? 188.568 175.819 168.818 1.00 149.11 ? 211  ASN A ND2 1 
ATOM   1486 N N   . ASP A 1 194  ? 185.160 173.705 171.025 1.00 135.30 ? 212  ASP A N   1 
ATOM   1487 C CA  . ASP A 1 194  ? 184.133 173.885 172.045 1.00 136.75 ? 212  ASP A CA  1 
ATOM   1488 C C   . ASP A 1 194  ? 182.733 173.521 171.558 1.00 131.06 ? 212  ASP A C   1 
ATOM   1489 O O   . ASP A 1 194  ? 181.765 173.755 172.292 1.00 131.53 ? 212  ASP A O   1 
ATOM   1490 C CB  . ASP A 1 194  ? 184.139 175.336 172.549 1.00 146.95 ? 212  ASP A CB  1 
ATOM   1491 C CG  . ASP A 1 194  ? 183.691 175.462 173.997 1.00 161.56 ? 212  ASP A CG  1 
ATOM   1492 O OD1 . ASP A 1 194  ? 183.111 174.501 174.546 1.00 161.75 ? 212  ASP A OD1 1 
ATOM   1493 O OD2 . ASP A 1 194  ? 183.922 176.536 174.592 1.00 172.50 ? 212  ASP A OD2 1 
ATOM   1494 N N   . GLN A 1 195  ? 182.592 172.953 170.361 1.00 126.80 ? 213  GLN A N   1 
ATOM   1495 C CA  . GLN A 1 195  ? 181.311 172.579 169.784 1.00 122.22 ? 213  GLN A CA  1 
ATOM   1496 C C   . GLN A 1 195  ? 181.127 171.069 169.847 1.00 116.31 ? 213  GLN A C   1 
ATOM   1497 O O   . GLN A 1 195  ? 182.095 170.304 169.793 1.00 120.66 ? 213  GLN A O   1 
ATOM   1498 C CB  . GLN A 1 195  ? 181.209 173.044 168.329 1.00 122.11 ? 213  GLN A CB  1 
ATOM   1499 C CG  . GLN A 1 195  ? 180.576 174.409 168.157 1.00 130.00 ? 213  GLN A CG  1 
ATOM   1500 C CD  . GLN A 1 195  ? 181.411 175.513 168.771 1.00 140.97 ? 213  GLN A CD  1 
ATOM   1501 O OE1 . GLN A 1 195  ? 182.570 175.704 168.405 1.00 142.10 ? 213  GLN A OE1 1 
ATOM   1502 N NE2 . GLN A 1 195  ? 180.825 176.250 169.707 1.00 140.29 ? 213  GLN A NE2 1 
ATOM   1503 N N   . THR A 1 196  ? 179.865 170.655 169.947 1.00 107.43 ? 214  THR A N   1 
ATOM   1504 C CA  . THR A 1 196  ? 179.476 169.255 170.045 1.00 106.51 ? 214  THR A CA  1 
ATOM   1505 C C   . THR A 1 196  ? 178.681 168.868 168.808 1.00 103.54 ? 214  THR A C   1 
ATOM   1506 O O   . THR A 1 196  ? 177.804 169.620 168.371 1.00 106.01 ? 214  THR A O   1 
ATOM   1507 C CB  . THR A 1 196  ? 178.641 169.009 171.304 1.00 113.83 ? 214  THR A CB  1 
ATOM   1508 O OG1 . THR A 1 196  ? 179.232 169.698 172.412 1.00 118.83 ? 214  THR A OG1 1 
ATOM   1509 C CG2 . THR A 1 196  ? 178.562 167.522 171.618 1.00 108.36 ? 214  THR A CG2 1 
ATOM   1510 N N   . TYR A 1 197  ? 178.994 167.701 168.248 1.00 99.56  ? 215  TYR A N   1 
ATOM   1511 C CA  . TYR A 1 197  ? 178.319 167.159 167.075 1.00 99.44  ? 215  TYR A CA  1 
ATOM   1512 C C   . TYR A 1 197  ? 177.809 165.765 167.402 1.00 97.70  ? 215  TYR A C   1 
ATOM   1513 O O   . TYR A 1 197  ? 178.562 164.930 167.910 1.00 101.70 ? 215  TYR A O   1 
ATOM   1514 C CB  . TYR A 1 197  ? 179.268 167.125 165.878 1.00 94.24  ? 215  TYR A CB  1 
ATOM   1515 C CG  . TYR A 1 197  ? 179.774 168.494 165.492 1.00 98.55  ? 215  TYR A CG  1 
ATOM   1516 C CD1 . TYR A 1 197  ? 179.054 169.299 164.623 1.00 104.26 ? 215  TYR A CD1 1 
ATOM   1517 C CD2 . TYR A 1 197  ? 180.956 168.993 166.014 1.00 95.14  ? 215  TYR A CD2 1 
ATOM   1518 C CE1 . TYR A 1 197  ? 179.506 170.554 164.272 1.00 106.95 ? 215  TYR A CE1 1 
ATOM   1519 C CE2 . TYR A 1 197  ? 181.415 170.246 165.668 1.00 95.05  ? 215  TYR A CE2 1 
ATOM   1520 C CZ  . TYR A 1 197  ? 180.687 171.022 164.799 1.00 104.03 ? 215  TYR A CZ  1 
ATOM   1521 O OH  . TYR A 1 197  ? 181.145 172.272 164.456 1.00 108.36 ? 215  TYR A OH  1 
ATOM   1522 N N   . TYR A 1 198  ? 176.539 165.513 167.098 1.00 93.96  ? 216  TYR A N   1 
ATOM   1523 C CA  . TYR A 1 198  ? 175.833 164.323 167.545 1.00 90.85  ? 216  TYR A CA  1 
ATOM   1524 C C   . TYR A 1 198  ? 175.567 163.374 166.384 1.00 85.43  ? 216  TYR A C   1 
ATOM   1525 O O   . TYR A 1 198  ? 175.494 163.778 165.221 1.00 86.91  ? 216  TYR A O   1 
ATOM   1526 C CB  . TYR A 1 198  ? 174.506 164.702 168.209 1.00 97.44  ? 216  TYR A CB  1 
ATOM   1527 C CG  . TYR A 1 198  ? 174.643 165.723 169.315 1.00 107.30 ? 216  TYR A CG  1 
ATOM   1528 C CD1 . TYR A 1 198  ? 174.854 165.328 170.627 1.00 109.16 ? 216  TYR A CD1 1 
ATOM   1529 C CD2 . TYR A 1 198  ? 174.564 167.082 169.047 1.00 113.49 ? 216  TYR A CD2 1 
ATOM   1530 C CE1 . TYR A 1 198  ? 174.981 166.256 171.639 1.00 115.92 ? 216  TYR A CE1 1 
ATOM   1531 C CE2 . TYR A 1 198  ? 174.690 168.016 170.053 1.00 120.41 ? 216  TYR A CE2 1 
ATOM   1532 C CZ  . TYR A 1 198  ? 174.899 167.598 171.347 1.00 122.32 ? 216  TYR A CZ  1 
ATOM   1533 O OH  . TYR A 1 198  ? 175.025 168.525 172.354 1.00 125.98 ? 216  TYR A OH  1 
ATOM   1534 N N   . GLN A 1 199  ? 175.428 162.095 166.723 1.00 87.58  ? 217  GLN A N   1 
ATOM   1535 C CA  . GLN A 1 199  ? 175.001 161.078 165.766 1.00 86.13  ? 217  GLN A CA  1 
ATOM   1536 C C   . GLN A 1 199  ? 174.281 159.987 166.541 1.00 87.53  ? 217  GLN A C   1 
ATOM   1537 O O   . GLN A 1 199  ? 174.882 159.349 167.407 1.00 89.89  ? 217  GLN A O   1 
ATOM   1538 C CB  . GLN A 1 199  ? 176.193 160.500 164.996 1.00 87.61  ? 217  GLN A CB  1 
ATOM   1539 C CG  . GLN A 1 199  ? 175.841 159.427 163.959 1.00 92.30  ? 217  GLN A CG  1 
ATOM   1540 C CD  . GLN A 1 199  ? 175.108 159.999 162.766 1.00 101.67 ? 217  GLN A CD  1 
ATOM   1541 O OE1 . GLN A 1 199  ? 175.711 160.619 161.891 1.00 98.48  ? 217  GLN A OE1 1 
ATOM   1542 N NE2 . GLN A 1 199  ? 173.797 159.802 162.728 1.00 108.24 ? 217  GLN A NE2 1 
ATOM   1543 N N   . SER A 1 200  ? 173.011 159.767 166.224 1.00 85.14  ? 218  SER A N   1 
ATOM   1544 C CA  . SER A 1 200  ? 172.204 158.753 166.887 1.00 87.57  ? 218  SER A CA  1 
ATOM   1545 C C   . SER A 1 200  ? 172.243 157.454 166.095 1.00 83.59  ? 218  SER A C   1 
ATOM   1546 O O   . SER A 1 200  ? 172.188 157.469 164.863 1.00 94.83  ? 218  SER A O   1 
ATOM   1547 C CB  . SER A 1 200  ? 170.757 159.223 167.034 1.00 96.62  ? 218  SER A CB  1 
ATOM   1548 O OG  . SER A 1 200  ? 170.068 159.131 165.800 1.00 104.25 ? 218  SER A OG  1 
ATOM   1549 N N   . PHE A 1 201  ? 172.352 156.333 166.809 1.00 77.35  ? 219  PHE A N   1 
ATOM   1550 C CA  . PHE A 1 201  ? 172.213 155.015 166.205 1.00 78.34  ? 219  PHE A CA  1 
ATOM   1551 C C   . PHE A 1 201  ? 171.368 154.141 167.117 1.00 84.58  ? 219  PHE A C   1 
ATOM   1552 O O   . PHE A 1 201  ? 171.529 154.168 168.339 1.00 89.42  ? 219  PHE A O   1 
ATOM   1553 C CB  . PHE A 1 201  ? 173.576 154.357 165.932 1.00 75.82  ? 219  PHE A CB  1 
ATOM   1554 C CG  . PHE A 1 201  ? 174.366 154.023 167.167 1.00 75.92  ? 219  PHE A CG  1 
ATOM   1555 C CD1 . PHE A 1 201  ? 175.187 154.964 167.759 1.00 80.75  ? 219  PHE A CD1 1 
ATOM   1556 C CD2 . PHE A 1 201  ? 174.319 152.751 167.711 1.00 79.09  ? 219  PHE A CD2 1 
ATOM   1557 C CE1 . PHE A 1 201  ? 175.924 154.649 168.884 1.00 76.80  ? 219  PHE A CE1 1 
ATOM   1558 C CE2 . PHE A 1 201  ? 175.054 152.434 168.835 1.00 78.73  ? 219  PHE A CE2 1 
ATOM   1559 C CZ  . PHE A 1 201  ? 175.860 153.383 169.418 1.00 71.42  ? 219  PHE A CZ  1 
ATOM   1560 N N   . GLN A 1 202  ? 170.468 153.370 166.518 1.00 87.94  ? 220  GLN A N   1 
ATOM   1561 C CA  . GLN A 1 202  ? 169.488 152.600 167.268 1.00 87.47  ? 220  GLN A CA  1 
ATOM   1562 C C   . GLN A 1 202  ? 170.034 151.223 167.618 1.00 86.32  ? 220  GLN A C   1 
ATOM   1563 O O   . GLN A 1 202  ? 170.824 150.645 166.867 1.00 91.44  ? 220  GLN A O   1 
ATOM   1564 C CB  . GLN A 1 202  ? 168.198 152.458 166.461 1.00 91.19  ? 220  GLN A CB  1 
ATOM   1565 C CG  . GLN A 1 202  ? 166.993 152.034 167.276 1.00 100.53 ? 220  GLN A CG  1 
ATOM   1566 C CD  . GLN A 1 202  ? 165.748 151.877 166.429 1.00 111.15 ? 220  GLN A CD  1 
ATOM   1567 O OE1 . GLN A 1 202  ? 165.725 152.271 165.263 1.00 114.21 ? 220  GLN A OE1 1 
ATOM   1568 N NE2 . GLN A 1 202  ? 164.704 151.302 167.011 1.00 113.83 ? 220  GLN A NE2 1 
ATOM   1569 N N   . VAL A 1 203  ? 169.610 150.712 168.771 1.00 82.13  ? 221  VAL A N   1 
ATOM   1570 C CA  . VAL A 1 203  ? 169.930 149.365 169.230 1.00 81.59  ? 221  VAL A CA  1 
ATOM   1571 C C   . VAL A 1 203  ? 168.619 148.704 169.625 1.00 93.57  ? 221  VAL A C   1 
ATOM   1572 O O   . VAL A 1 203  ? 167.876 149.240 170.458 1.00 102.43 ? 221  VAL A O   1 
ATOM   1573 C CB  . VAL A 1 203  ? 170.914 149.379 170.409 1.00 80.37  ? 221  VAL A CB  1 
ATOM   1574 C CG1 . VAL A 1 203  ? 171.144 147.966 170.923 1.00 88.22  ? 221  VAL A CG1 1 
ATOM   1575 C CG2 . VAL A 1 203  ? 172.227 150.032 170.003 1.00 86.60  ? 221  VAL A CG2 1 
ATOM   1576 N N   . SER A 1 204  ? 168.340 147.543 169.035 1.00 96.99  ? 222  SER A N   1 
ATOM   1577 C CA  . SER A 1 204  ? 167.083 146.843 169.255 1.00 102.82 ? 222  SER A CA  1 
ATOM   1578 C C   . SER A 1 204  ? 167.274 145.369 168.926 1.00 106.79 ? 222  SER A C   1 
ATOM   1579 O O   . SER A 1 204  ? 168.321 144.956 168.419 1.00 113.53 ? 222  SER A O   1 
ATOM   1580 C CB  . SER A 1 204  ? 165.960 147.452 168.411 1.00 104.58 ? 222  SER A CB  1 
ATOM   1581 O OG  . SER A 1 204  ? 165.742 148.809 168.751 1.00 106.69 ? 222  SER A OG  1 
ATOM   1582 N N   . GLU A 1 205  ? 166.248 144.576 169.220 1.00 110.34 ? 223  GLU A N   1 
ATOM   1583 C CA  . GLU A 1 205  ? 166.217 143.154 168.914 1.00 126.40 ? 223  GLU A CA  1 
ATOM   1584 C C   . GLU A 1 205  ? 165.454 142.910 167.616 1.00 140.38 ? 223  GLU A C   1 
ATOM   1585 O O   . GLU A 1 205  ? 164.687 143.754 167.147 1.00 145.51 ? 223  GLU A O   1 
ATOM   1586 C CB  . GLU A 1 205  ? 165.578 142.373 170.065 1.00 131.47 ? 223  GLU A CB  1 
ATOM   1587 C CG  . GLU A 1 205  ? 166.267 142.576 171.403 1.00 131.06 ? 223  GLU A CG  1 
ATOM   1588 C CD  . GLU A 1 205  ? 165.706 141.683 172.491 1.00 148.15 ? 223  GLU A CD  1 
ATOM   1589 O OE1 . GLU A 1 205  ? 164.777 140.901 172.202 1.00 157.77 ? 223  GLU A OE1 1 
ATOM   1590 O OE2 . GLU A 1 205  ? 166.195 141.762 173.637 1.00 151.27 ? 223  GLU A OE2 1 
ATOM   1591 N N   . TYR A 1 206  ? 165.680 141.732 167.031 1.00 143.48 ? 224  TYR A N   1 
ATOM   1592 C CA  . TYR A 1 206  ? 165.089 141.395 165.740 1.00 149.62 ? 224  TYR A CA  1 
ATOM   1593 C C   . TYR A 1 206  ? 163.566 141.343 165.821 1.00 156.28 ? 224  TYR A C   1 
ATOM   1594 O O   . TYR A 1 206  ? 162.892 142.207 165.251 1.00 155.90 ? 224  TYR A O   1 
ATOM   1595 C CB  . TYR A 1 206  ? 165.663 140.066 165.227 1.00 148.81 ? 224  TYR A CB  1 
ATOM   1596 C CG  . TYR A 1 206  ? 165.824 139.989 163.728 1.00 158.51 ? 224  TYR A CG  1 
ATOM   1597 C CD1 . TYR A 1 206  ? 164.728 140.089 162.883 1.00 164.44 ? 224  TYR A CD1 1 
ATOM   1598 C CD2 . TYR A 1 206  ? 167.074 139.792 163.158 1.00 156.74 ? 224  TYR A CD2 1 
ATOM   1599 C CE1 . TYR A 1 206  ? 164.874 140.012 161.510 1.00 163.81 ? 224  TYR A CE1 1 
ATOM   1600 C CE2 . TYR A 1 206  ? 167.230 139.711 161.788 1.00 160.84 ? 224  TYR A CE2 1 
ATOM   1601 C CZ  . TYR A 1 206  ? 166.128 139.822 160.968 1.00 161.17 ? 224  TYR A CZ  1 
ATOM   1602 O OH  . TYR A 1 206  ? 166.281 139.743 159.603 1.00 144.86 ? 224  TYR A OH  1 
ATOM   1603 N N   . VAL A 1 207  ? 163.025 140.377 166.572 1.00 158.41 ? 225  VAL A N   1 
ATOM   1604 C CA  . VAL A 1 207  ? 161.587 140.132 166.674 1.00 161.99 ? 225  VAL A CA  1 
ATOM   1605 C C   . VAL A 1 207  ? 160.969 140.063 165.281 1.00 169.94 ? 225  VAL A C   1 
ATOM   1606 O O   . VAL A 1 207  ? 160.225 140.963 164.874 1.00 174.47 ? 225  VAL A O   1 
ATOM   1607 C CB  . VAL A 1 207  ? 160.907 141.213 167.536 1.00 164.12 ? 225  VAL A CB  1 
ATOM   1608 C CG1 . VAL A 1 207  ? 159.499 140.775 167.931 1.00 170.61 ? 225  VAL A CG1 1 
ATOM   1609 C CG2 . VAL A 1 207  ? 161.748 141.509 168.774 1.00 159.27 ? 225  VAL A CG2 1 
ATOM   1610 N N   . LEU A 1 208  ? 161.265 138.994 164.547 1.00 172.60 ? 226  LEU A N   1 
ATOM   1611 C CA  . LEU A 1 208  ? 160.855 138.952 163.147 1.00 183.07 ? 226  LEU A CA  1 
ATOM   1612 C C   . LEU A 1 208  ? 159.386 138.538 163.028 1.00 190.17 ? 226  LEU A C   1 
ATOM   1613 O O   . LEU A 1 208  ? 158.962 137.587 163.692 1.00 190.37 ? 226  LEU A O   1 
ATOM   1614 C CB  . LEU A 1 208  ? 161.725 137.974 162.355 1.00 181.29 ? 226  LEU A CB  1 
ATOM   1615 C CG  . LEU A 1 208  ? 161.494 136.455 162.429 1.00 181.36 ? 226  LEU A CG  1 
ATOM   1616 C CD1 . LEU A 1 208  ? 162.374 135.751 161.408 1.00 179.70 ? 226  LEU A CD1 1 
ATOM   1617 C CD2 . LEU A 1 208  ? 161.742 135.911 163.823 1.00 169.68 ? 226  LEU A CD2 1 
ATOM   1618 N N   . PRO A 1 209  ? 158.557 139.195 162.209 1.00 193.54 ? 227  PRO A N   1 
ATOM   1619 C CA  . PRO A 1 209  ? 157.258 138.604 161.870 1.00 200.52 ? 227  PRO A CA  1 
ATOM   1620 C C   . PRO A 1 209  ? 157.416 137.524 160.812 1.00 208.74 ? 227  PRO A C   1 
ATOM   1621 O O   . PRO A 1 209  ? 158.223 137.646 159.887 1.00 206.79 ? 227  PRO A O   1 
ATOM   1622 C CB  . PRO A 1 209  ? 156.451 139.793 161.338 1.00 206.35 ? 227  PRO A CB  1 
ATOM   1623 C CG  . PRO A 1 209  ? 157.463 140.710 160.790 1.00 202.78 ? 227  PRO A CG  1 
ATOM   1624 C CD  . PRO A 1 209  ? 158.689 140.553 161.643 1.00 193.96 ? 227  PRO A CD  1 
ATOM   1625 N N   . LYS A 1 210  ? 156.632 136.455 160.955 1.00 217.81 ? 228  LYS A N   1 
ATOM   1626 C CA  . LYS A 1 210  ? 156.741 135.335 160.024 1.00 228.60 ? 228  LYS A CA  1 
ATOM   1627 C C   . LYS A 1 210  ? 156.140 135.643 158.658 1.00 230.97 ? 228  LYS A C   1 
ATOM   1628 O O   . LYS A 1 210  ? 156.458 134.943 157.690 1.00 229.65 ? 228  LYS A O   1 
ATOM   1629 C CB  . LYS A 1 210  ? 156.082 134.067 160.588 1.00 233.01 ? 228  LYS A CB  1 
ATOM   1630 C CG  . LYS A 1 210  ? 154.709 134.235 161.230 1.00 235.98 ? 228  LYS A CG  1 
ATOM   1631 C CD  . LYS A 1 210  ? 154.055 132.876 161.475 1.00 242.74 ? 228  LYS A CD  1 
ATOM   1632 C CE  . LYS A 1 210  ? 153.309 132.335 160.258 1.00 247.73 ? 228  LYS A CE  1 
ATOM   1633 N NZ  . LYS A 1 210  ? 152.218 133.229 159.772 1.00 250.82 ? 228  LYS A NZ  1 
ATOM   1634 N N   . PHE A 1 211  ? 155.281 136.658 158.556 1.00 231.45 ? 229  PHE A N   1 
ATOM   1635 C CA  . PHE A 1 211  ? 154.732 137.088 157.278 1.00 232.85 ? 229  PHE A CA  1 
ATOM   1636 C C   . PHE A 1 211  ? 154.618 138.604 157.262 1.00 234.90 ? 229  PHE A C   1 
ATOM   1637 O O   . PHE A 1 211  ? 154.493 139.244 158.309 1.00 234.43 ? 229  PHE A O   1 
ATOM   1638 C CB  . PHE A 1 211  ? 153.363 136.454 157.002 1.00 236.06 ? 229  PHE A CB  1 
ATOM   1639 C CG  . PHE A 1 211  ? 152.249 137.015 157.840 1.00 238.94 ? 229  PHE A CG  1 
ATOM   1640 C CD1 . PHE A 1 211  ? 152.103 136.639 159.164 1.00 239.65 ? 229  PHE A CD1 1 
ATOM   1641 C CD2 . PHE A 1 211  ? 151.340 137.909 157.299 1.00 242.09 ? 229  PHE A CD2 1 
ATOM   1642 C CE1 . PHE A 1 211  ? 151.077 137.150 159.935 1.00 243.95 ? 229  PHE A CE1 1 
ATOM   1643 C CE2 . PHE A 1 211  ? 150.312 138.423 158.066 1.00 246.80 ? 229  PHE A CE2 1 
ATOM   1644 C CZ  . PHE A 1 211  ? 150.180 138.042 159.385 1.00 247.98 ? 229  PHE A CZ  1 
ATOM   1645 N N   . GLU A 1 212  ? 154.662 139.165 156.055 1.00 237.74 ? 230  GLU A N   1 
ATOM   1646 C CA  . GLU A 1 212  ? 154.606 140.601 155.830 1.00 239.19 ? 230  GLU A CA  1 
ATOM   1647 C C   . GLU A 1 212  ? 153.492 140.924 154.845 1.00 242.39 ? 230  GLU A C   1 
ATOM   1648 O O   . GLU A 1 212  ? 153.260 140.189 153.880 1.00 243.94 ? 230  GLU A O   1 
ATOM   1649 C CB  . GLU A 1 212  ? 155.943 141.134 155.298 1.00 239.37 ? 230  GLU A CB  1 
ATOM   1650 C CG  . GLU A 1 212  ? 156.549 140.298 154.177 1.00 239.54 ? 230  GLU A CG  1 
ATOM   1651 C CD  . GLU A 1 212  ? 157.762 140.954 153.545 1.00 239.93 ? 230  GLU A CD  1 
ATOM   1652 O OE1 . GLU A 1 212  ? 158.105 142.088 153.942 1.00 239.08 ? 230  GLU A OE1 1 
ATOM   1653 O OE2 . GLU A 1 212  ? 158.375 140.333 152.652 1.00 237.74 ? 230  GLU A OE2 1 
ATOM   1654 N N   . VAL A 1 213  ? 152.816 142.043 155.097 1.00 243.56 ? 231  VAL A N   1 
ATOM   1655 C CA  . VAL A 1 213  ? 151.672 142.492 154.312 1.00 246.53 ? 231  VAL A CA  1 
ATOM   1656 C C   . VAL A 1 213  ? 152.069 143.759 153.571 1.00 244.88 ? 231  VAL A C   1 
ATOM   1657 O O   . VAL A 1 213  ? 152.585 144.704 154.180 1.00 244.21 ? 231  VAL A O   1 
ATOM   1658 C CB  . VAL A 1 213  ? 150.441 142.743 155.202 1.00 250.20 ? 231  VAL A CB  1 
ATOM   1659 C CG1 . VAL A 1 213  ? 149.193 142.960 154.346 1.00 253.28 ? 231  VAL A CG1 1 
ATOM   1660 C CG2 . VAL A 1 213  ? 150.245 141.588 156.178 1.00 250.09 ? 231  VAL A CG2 1 
ATOM   1661 N N   . THR A 1 214  ? 151.835 143.771 152.260 1.00 246.17 ? 232  THR A N   1 
ATOM   1662 C CA  . THR A 1 214  ? 152.037 144.943 151.418 1.00 247.02 ? 232  THR A CA  1 
ATOM   1663 C C   . THR A 1 214  ? 150.705 145.345 150.802 1.00 248.12 ? 232  THR A C   1 
ATOM   1664 O O   . THR A 1 214  ? 149.986 144.503 150.248 1.00 249.49 ? 232  THR A O   1 
ATOM   1665 C CB  . THR A 1 214  ? 153.075 144.679 150.324 1.00 247.55 ? 232  THR A CB  1 
ATOM   1666 O OG1 . THR A 1 214  ? 152.896 143.361 149.795 1.00 249.83 ? 232  THR A OG1 1 
ATOM   1667 C CG2 . THR A 1 214  ? 154.488 144.814 150.878 1.00 244.58 ? 232  THR A CG2 1 
ATOM   1668 N N   . LEU A 1 215  ? 150.382 146.632 150.915 1.00 247.88 ? 233  LEU A N   1 
ATOM   1669 C CA  . LEU A 1 215  ? 149.125 147.213 150.448 1.00 250.26 ? 233  LEU A CA  1 
ATOM   1670 C C   . LEU A 1 215  ? 149.426 148.149 149.283 1.00 250.92 ? 233  LEU A C   1 
ATOM   1671 O O   . LEU A 1 215  ? 149.873 149.283 149.484 1.00 248.98 ? 233  LEU A O   1 
ATOM   1672 C CB  . LEU A 1 215  ? 148.419 147.936 151.591 1.00 248.91 ? 233  LEU A CB  1 
ATOM   1673 C CG  . LEU A 1 215  ? 147.108 148.665 151.306 1.00 250.13 ? 233  LEU A CG  1 
ATOM   1674 C CD1 . LEU A 1 215  ? 146.064 147.793 150.624 1.00 251.84 ? 233  LEU A CD1 1 
ATOM   1675 C CD2 . LEU A 1 215  ? 146.561 149.203 152.610 1.00 253.19 ? 233  LEU A CD2 1 
ATOM   1676 N N   . GLN A 1 216  ? 149.176 147.667 148.067 1.00 251.86 ? 234  GLN A N   1 
ATOM   1677 C CA  . GLN A 1 216  ? 149.393 148.445 146.852 1.00 251.08 ? 234  GLN A CA  1 
ATOM   1678 C C   . GLN A 1 216  ? 148.099 149.162 146.490 1.00 252.92 ? 234  GLN A C   1 
ATOM   1679 O O   . GLN A 1 216  ? 147.105 148.519 146.135 1.00 253.36 ? 234  GLN A O   1 
ATOM   1680 C CB  . GLN A 1 216  ? 149.847 147.539 145.711 1.00 249.74 ? 234  GLN A CB  1 
ATOM   1681 C CG  . GLN A 1 216  ? 150.126 148.277 144.415 1.00 250.10 ? 234  GLN A CG  1 
ATOM   1682 C CD  . GLN A 1 216  ? 148.974 148.172 143.433 1.00 251.78 ? 234  GLN A CD  1 
ATOM   1683 O OE1 . GLN A 1 216  ? 148.630 147.081 142.979 1.00 251.41 ? 234  GLN A OE1 1 
ATOM   1684 N NE2 . GLN A 1 216  ? 148.373 149.309 143.098 1.00 253.25 ? 234  GLN A NE2 1 
ATOM   1685 N N   . THR A 1 217  ? 148.109 150.490 146.590 1.00 252.54 ? 235  THR A N   1 
ATOM   1686 C CA  . THR A 1 217  ? 146.999 151.339 146.187 1.00 253.04 ? 235  THR A CA  1 
ATOM   1687 C C   . THR A 1 217  ? 147.541 152.532 145.414 1.00 256.30 ? 235  THR A C   1 
ATOM   1688 O O   . THR A 1 217  ? 148.712 152.890 145.576 1.00 256.42 ? 235  THR A O   1 
ATOM   1689 C CB  . THR A 1 217  ? 146.198 151.859 147.392 1.00 252.24 ? 235  THR A CB  1 
ATOM   1690 O OG1 . THR A 1 217  ? 146.779 153.085 147.855 1.00 255.54 ? 235  THR A OG1 1 
ATOM   1691 C CG2 . THR A 1 217  ? 146.194 150.859 148.534 1.00 249.56 ? 235  THR A CG2 1 
ATOM   1692 N N   . PRO A 1 218  ? 146.728 153.169 144.568 1.00 257.96 ? 236  PRO A N   1 
ATOM   1693 C CA  . PRO A 1 218  ? 147.155 154.449 143.996 1.00 258.48 ? 236  PRO A CA  1 
ATOM   1694 C C   . PRO A 1 218  ? 147.239 155.518 145.074 1.00 260.34 ? 236  PRO A C   1 
ATOM   1695 O O   . PRO A 1 218  ? 146.437 155.555 146.009 1.00 263.82 ? 236  PRO A O   1 
ATOM   1696 C CB  . PRO A 1 218  ? 146.062 154.771 142.971 1.00 257.98 ? 236  PRO A CB  1 
ATOM   1697 C CG  . PRO A 1 218  ? 144.877 154.014 143.429 1.00 254.93 ? 236  PRO A CG  1 
ATOM   1698 C CD  . PRO A 1 218  ? 145.409 152.762 144.046 1.00 255.74 ? 236  PRO A CD  1 
ATOM   1699 N N   . LEU A 1 219  ? 148.230 156.399 144.932 1.00 257.26 ? 237  LEU A N   1 
ATOM   1700 C CA  . LEU A 1 219  ? 148.414 157.450 145.927 1.00 257.38 ? 237  LEU A CA  1 
ATOM   1701 C C   . LEU A 1 219  ? 147.307 158.492 145.838 1.00 261.07 ? 237  LEU A C   1 
ATOM   1702 O O   . LEU A 1 219  ? 146.792 158.946 146.867 1.00 262.81 ? 237  LEU A O   1 
ATOM   1703 C CB  . LEU A 1 219  ? 149.783 158.108 145.750 1.00 252.62 ? 237  LEU A CB  1 
ATOM   1704 C CG  . LEU A 1 219  ? 150.246 159.074 146.848 1.00 251.82 ? 237  LEU A CG  1 
ATOM   1705 C CD1 . LEU A 1 219  ? 150.388 158.376 148.197 1.00 250.54 ? 237  LEU A CD1 1 
ATOM   1706 C CD2 . LEU A 1 219  ? 151.554 159.739 146.448 1.00 249.44 ? 237  LEU A CD2 1 
ATOM   1707 N N   . TYR A 1 220  ? 146.931 158.879 144.620 1.00 260.90 ? 238  TYR A N   1 
ATOM   1708 C CA  . TYR A 1 220  ? 145.917 159.893 144.368 1.00 261.70 ? 238  TYR A CA  1 
ATOM   1709 C C   . TYR A 1 220  ? 144.693 159.237 143.743 1.00 262.05 ? 238  TYR A C   1 
ATOM   1710 O O   . TYR A 1 220  ? 144.813 158.298 142.950 1.00 262.36 ? 238  TYR A O   1 
ATOM   1711 C CB  . TYR A 1 220  ? 146.445 161.002 143.435 1.00 261.97 ? 238  TYR A CB  1 
ATOM   1712 C CG  . TYR A 1 220  ? 147.616 161.836 143.951 1.00 263.05 ? 238  TYR A CG  1 
ATOM   1713 C CD1 . TYR A 1 220  ? 148.098 161.709 145.251 1.00 263.52 ? 238  TYR A CD1 1 
ATOM   1714 C CD2 . TYR A 1 220  ? 148.240 162.756 143.118 1.00 263.25 ? 238  TYR A CD2 1 
ATOM   1715 C CE1 . TYR A 1 220  ? 149.157 162.472 145.702 1.00 263.83 ? 238  TYR A CE1 1 
ATOM   1716 C CE2 . TYR A 1 220  ? 149.302 163.522 143.562 1.00 264.62 ? 238  TYR A CE2 1 
ATOM   1717 C CZ  . TYR A 1 220  ? 149.755 163.375 144.854 1.00 264.86 ? 238  TYR A CZ  1 
ATOM   1718 O OH  . TYR A 1 220  ? 150.812 164.135 145.301 1.00 264.73 ? 238  TYR A OH  1 
ATOM   1719 N N   . CYS A 1 221  ? 143.514 159.738 144.110 1.00 261.40 ? 239  CYS A N   1 
ATOM   1720 C CA  . CYS A 1 221  ? 142.249 159.177 143.657 1.00 260.93 ? 239  CYS A CA  1 
ATOM   1721 C C   . CYS A 1 221  ? 141.253 160.305 143.420 1.00 258.17 ? 239  CYS A C   1 
ATOM   1722 O O   . CYS A 1 221  ? 141.382 161.401 143.971 1.00 257.92 ? 239  CYS A O   1 
ATOM   1723 C CB  . CYS A 1 221  ? 141.689 158.173 144.675 1.00 260.16 ? 239  CYS A CB  1 
ATOM   1724 S SG  . CYS A 1 221  ? 140.133 157.384 144.192 1.00 256.06 ? 239  CYS A SG  1 
ATOM   1725 N N   . SER A 1 222  ? 140.258 160.019 142.580 1.00 255.30 ? 240  SER A N   1 
ATOM   1726 C CA  . SER A 1 222  ? 139.179 160.946 142.273 1.00 254.67 ? 240  SER A CA  1 
ATOM   1727 C C   . SER A 1 222  ? 137.850 160.210 142.356 1.00 256.10 ? 240  SER A C   1 
ATOM   1728 O O   . SER A 1 222  ? 137.772 158.997 142.148 1.00 256.76 ? 240  SER A O   1 
ATOM   1729 C CB  . SER A 1 222  ? 139.345 161.568 140.881 1.00 256.15 ? 240  SER A CB  1 
ATOM   1730 O OG  . SER A 1 222  ? 138.183 162.287 140.505 1.00 257.69 ? 240  SER A OG  1 
ATOM   1731 N N   . MET A 1 223  ? 136.794 160.965 142.662 1.00 257.07 ? 241  MET A N   1 
ATOM   1732 C CA  . MET A 1 223  ? 135.480 160.354 142.838 1.00 256.31 ? 241  MET A CA  1 
ATOM   1733 C C   . MET A 1 223  ? 134.904 159.828 141.529 1.00 259.80 ? 241  MET A C   1 
ATOM   1734 O O   . MET A 1 223  ? 134.108 158.884 141.557 1.00 260.31 ? 241  MET A O   1 
ATOM   1735 C CB  . MET A 1 223  ? 134.469 161.335 143.455 1.00 251.23 ? 241  MET A CB  1 
ATOM   1736 C CG  . MET A 1 223  ? 134.417 162.761 142.879 1.00 250.47 ? 241  MET A CG  1 
ATOM   1737 S SD  . MET A 1 223  ? 135.967 163.683 142.826 1.00 256.31 ? 241  MET A SD  1 
ATOM   1738 C CE  . MET A 1 223  ? 136.404 163.707 144.565 1.00 253.12 ? 241  MET A CE  1 
ATOM   1739 N N   . ASN A 1 224  ? 135.285 160.408 140.389 1.00 262.52 ? 242  ASN A N   1 
ATOM   1740 C CA  . ASN A 1 224  ? 134.684 160.017 139.115 1.00 264.71 ? 242  ASN A CA  1 
ATOM   1741 C C   . ASN A 1 224  ? 135.008 158.584 138.708 1.00 268.67 ? 242  ASN A C   1 
ATOM   1742 O O   . ASN A 1 224  ? 134.282 158.014 137.887 1.00 269.45 ? 242  ASN A O   1 
ATOM   1743 C CB  . ASN A 1 224  ? 135.118 160.965 137.987 1.00 264.06 ? 242  ASN A CB  1 
ATOM   1744 C CG  . ASN A 1 224  ? 136.628 161.150 137.905 1.00 263.64 ? 242  ASN A CG  1 
ATOM   1745 O OD1 . ASN A 1 224  ? 137.401 160.268 138.281 1.00 263.93 ? 242  ASN A OD1 1 
ATOM   1746 N ND2 . ASN A 1 224  ? 137.051 162.304 137.404 1.00 263.97 ? 242  ASN A ND2 1 
ATOM   1747 N N   . SER A 1 225  ? 136.068 157.990 139.251 1.00 269.79 ? 243  SER A N   1 
ATOM   1748 C CA  . SER A 1 225  ? 136.442 156.638 138.860 1.00 269.30 ? 243  SER A CA  1 
ATOM   1749 C C   . SER A 1 225  ? 135.440 155.631 139.412 1.00 268.94 ? 243  SER A C   1 
ATOM   1750 O O   . SER A 1 225  ? 135.110 155.654 140.602 1.00 268.72 ? 243  SER A O   1 
ATOM   1751 C CB  . SER A 1 225  ? 137.849 156.316 139.360 1.00 266.93 ? 243  SER A CB  1 
ATOM   1752 O OG  . SER A 1 225  ? 138.130 154.931 139.250 1.00 265.20 ? 243  SER A OG  1 
ATOM   1753 N N   . LYS A 1 226  ? 134.952 154.744 138.540 1.00 268.18 ? 244  LYS A N   1 
ATOM   1754 C CA  . LYS A 1 226  ? 134.006 153.722 138.978 1.00 264.44 ? 244  LYS A CA  1 
ATOM   1755 C C   . LYS A 1 226  ? 134.676 152.724 139.915 1.00 257.92 ? 244  LYS A C   1 
ATOM   1756 O O   . LYS A 1 226  ? 134.172 152.454 141.011 1.00 253.04 ? 244  LYS A O   1 
ATOM   1757 C CB  . LYS A 1 226  ? 133.403 153.014 137.758 1.00 258.92 ? 244  LYS A CB  1 
ATOM   1758 C CG  . LYS A 1 226  ? 132.558 151.752 138.040 1.00 252.12 ? 244  LYS A CG  1 
ATOM   1759 C CD  . LYS A 1 226  ? 131.339 152.029 138.920 1.00 251.66 ? 244  LYS A CD  1 
ATOM   1760 C CE  . LYS A 1 226  ? 130.707 150.735 139.415 1.00 244.37 ? 244  LYS A CE  1 
ATOM   1761 N NZ  . LYS A 1 226  ? 129.633 150.986 140.415 1.00 241.70 ? 244  LYS A NZ  1 
ATOM   1762 N N   . HIS A 1 227  ? 135.818 152.178 139.503 1.00 255.26 ? 245  HIS A N   1 
ATOM   1763 C CA  . HIS A 1 227  ? 136.534 151.150 140.248 1.00 245.37 ? 245  HIS A CA  1 
ATOM   1764 C C   . HIS A 1 227  ? 137.786 151.759 140.860 1.00 244.26 ? 245  HIS A C   1 
ATOM   1765 O O   . HIS A 1 227  ? 138.738 152.080 140.139 1.00 243.11 ? 245  HIS A O   1 
ATOM   1766 C CB  . HIS A 1 227  ? 136.905 149.977 139.341 1.00 237.54 ? 245  HIS A CB  1 
ATOM   1767 C CG  . HIS A 1 227  ? 135.834 148.938 139.225 1.00 232.75 ? 245  HIS A CG  1 
ATOM   1768 N ND1 . HIS A 1 227  ? 135.388 148.206 140.304 1.00 230.02 ? 245  HIS A ND1 1 
ATOM   1769 C CD2 . HIS A 1 227  ? 135.123 148.505 138.157 1.00 227.40 ? 245  HIS A CD2 1 
ATOM   1770 C CE1 . HIS A 1 227  ? 134.447 147.369 139.907 1.00 222.61 ? 245  HIS A CE1 1 
ATOM   1771 N NE2 . HIS A 1 227  ? 134.267 147.530 138.608 1.00 221.09 ? 245  HIS A NE2 1 
ATOM   1772 N N   . LEU A 1 228  ? 137.780 151.921 142.181 1.00 241.15 ? 246  LEU A N   1 
ATOM   1773 C CA  . LEU A 1 228  ? 138.976 152.279 142.937 1.00 239.31 ? 246  LEU A CA  1 
ATOM   1774 C C   . LEU A 1 228  ? 139.619 150.974 143.390 1.00 237.98 ? 246  LEU A C   1 
ATOM   1775 O O   . LEU A 1 228  ? 139.141 150.338 144.333 1.00 237.59 ? 246  LEU A O   1 
ATOM   1776 C CB  . LEU A 1 228  ? 138.629 153.185 144.117 1.00 238.76 ? 246  LEU A CB  1 
ATOM   1777 C CG  . LEU A 1 228  ? 139.629 153.310 145.272 1.00 236.57 ? 246  LEU A CG  1 
ATOM   1778 C CD1 . LEU A 1 228  ? 140.996 153.748 144.769 1.00 239.01 ? 246  LEU A CD1 1 
ATOM   1779 C CD2 . LEU A 1 228  ? 139.101 154.290 146.305 1.00 237.18 ? 246  LEU A CD2 1 
ATOM   1780 N N   . ASN A 1 229  ? 140.686 150.574 142.707 1.00 238.72 ? 247  ASN A N   1 
ATOM   1781 C CA  . ASN A 1 229  ? 141.278 149.258 142.886 1.00 240.59 ? 247  ASN A CA  1 
ATOM   1782 C C   . ASN A 1 229  ? 142.407 149.293 143.911 1.00 243.72 ? 247  ASN A C   1 
ATOM   1783 O O   . ASN A 1 229  ? 142.980 150.343 144.213 1.00 243.59 ? 247  ASN A O   1 
ATOM   1784 C CB  . ASN A 1 229  ? 141.809 148.727 141.553 1.00 235.74 ? 247  ASN A CB  1 
ATOM   1785 C CG  . ASN A 1 229  ? 140.759 148.746 140.457 1.00 229.71 ? 247  ASN A CG  1 
ATOM   1786 O OD1 . ASN A 1 229  ? 140.204 149.796 140.136 1.00 228.43 ? 247  ASN A OD1 1 
ATOM   1787 N ND2 . ASN A 1 229  ? 140.485 147.584 139.875 1.00 222.29 ? 247  ASN A ND2 1 
ATOM   1788 N N   . GLY A 1 230  ? 142.715 148.116 144.447 1.00 247.16 ? 248  GLY A N   1 
ATOM   1789 C CA  . GLY A 1 230  ? 143.842 147.957 145.345 1.00 249.21 ? 248  GLY A CA  1 
ATOM   1790 C C   . GLY A 1 230  ? 144.138 146.490 145.544 1.00 250.08 ? 248  GLY A C   1 
ATOM   1791 O O   . GLY A 1 230  ? 143.304 145.625 145.254 1.00 247.44 ? 248  GLY A O   1 
ATOM   1792 N N   . THR A 1 231  ? 145.343 146.215 146.047 1.00 254.25 ? 249  THR A N   1 
ATOM   1793 C CA  . THR A 1 231  ? 145.833 144.853 146.228 1.00 255.22 ? 249  THR A CA  1 
ATOM   1794 C C   . THR A 1 231  ? 146.423 144.693 147.619 1.00 256.19 ? 249  THR A C   1 
ATOM   1795 O O   . THR A 1 231  ? 147.125 145.586 148.108 1.00 256.09 ? 249  THR A O   1 
ATOM   1796 C CB  . THR A 1 231  ? 146.892 144.496 145.180 1.00 254.17 ? 249  THR A CB  1 
ATOM   1797 O OG1 . THR A 1 231  ? 146.474 144.961 143.890 1.00 252.51 ? 249  THR A OG1 1 
ATOM   1798 C CG2 . THR A 1 231  ? 147.112 142.987 145.133 1.00 251.71 ? 249  THR A CG2 1 
ATOM   1799 N N   . ILE A 1 232  ? 146.138 143.548 148.239 1.00 256.67 ? 250  ILE A N   1 
ATOM   1800 C CA  . ILE A 1 232  ? 146.711 143.149 149.523 1.00 254.92 ? 250  ILE A CA  1 
ATOM   1801 C C   . ILE A 1 232  ? 147.496 141.870 149.286 1.00 254.23 ? 250  ILE A C   1 
ATOM   1802 O O   . ILE A 1 232  ? 146.933 140.871 148.820 1.00 254.30 ? 250  ILE A O   1 
ATOM   1803 C CB  . ILE A 1 232  ? 145.643 142.932 150.615 1.00 255.93 ? 250  ILE A CB  1 
ATOM   1804 C CG1 . ILE A 1 232  ? 144.371 142.251 150.061 1.00 256.64 ? 250  ILE A CG1 1 
ATOM   1805 C CG2 . ILE A 1 232  ? 145.309 144.257 151.319 1.00 257.34 ? 250  ILE A CG2 1 
ATOM   1806 C CD1 . ILE A 1 232  ? 143.251 142.091 151.051 1.00 258.92 ? 250  ILE A CD1 1 
ATOM   1807 N N   . THR A 1 233  ? 148.787 141.895 149.617 1.00 254.75 ? 251  THR A N   1 
ATOM   1808 C CA  . THR A 1 233  ? 149.686 140.761 149.413 1.00 255.80 ? 251  THR A CA  1 
ATOM   1809 C C   . THR A 1 233  ? 150.319 140.415 150.756 1.00 254.23 ? 251  THR A C   1 
ATOM   1810 O O   . THR A 1 233  ? 151.200 141.134 151.237 1.00 253.05 ? 251  THR A O   1 
ATOM   1811 C CB  . THR A 1 233  ? 150.745 141.088 148.363 1.00 255.70 ? 251  THR A CB  1 
ATOM   1812 O OG1 . THR A 1 233  ? 150.107 141.537 147.161 1.00 256.72 ? 251  THR A OG1 1 
ATOM   1813 C CG2 . THR A 1 233  ? 151.601 139.864 148.054 1.00 251.63 ? 251  THR A CG2 1 
ATOM   1814 N N   . ALA A 1 234  ? 149.852 139.323 151.361 1.00 252.80 ? 252  ALA A N   1 
ATOM   1815 C CA  . ALA A 1 234  ? 150.424 138.776 152.587 1.00 249.80 ? 252  ALA A CA  1 
ATOM   1816 C C   . ALA A 1 234  ? 151.321 137.609 152.196 1.00 247.25 ? 252  ALA A C   1 
ATOM   1817 O O   . ALA A 1 234  ? 150.832 136.569 151.743 1.00 247.01 ? 252  ALA A O   1 
ATOM   1818 C CB  . ALA A 1 234  ? 149.326 138.327 153.548 1.00 249.82 ? 252  ALA A CB  1 
ATOM   1819 N N   . LYS A 1 235  ? 152.631 137.782 152.378 1.00 244.18 ? 253  LYS A N   1 
ATOM   1820 C CA  . LYS A 1 235  ? 153.632 136.844 151.890 1.00 239.71 ? 253  LYS A CA  1 
ATOM   1821 C C   . LYS A 1 235  ? 154.570 136.457 153.022 1.00 237.64 ? 253  LYS A C   1 
ATOM   1822 O O   . LYS A 1 235  ? 154.928 137.293 153.857 1.00 237.90 ? 253  LYS A O   1 
ATOM   1823 C CB  . LYS A 1 235  ? 154.430 137.456 150.732 1.00 236.60 ? 253  LYS A CB  1 
ATOM   1824 C CG  . LYS A 1 235  ? 154.854 136.459 149.667 1.00 231.47 ? 253  LYS A CG  1 
ATOM   1825 C CD  . LYS A 1 235  ? 155.638 137.145 148.558 1.00 230.28 ? 253  LYS A CD  1 
ATOM   1826 C CE  . LYS A 1 235  ? 155.887 136.209 147.387 1.00 226.50 ? 253  LYS A CE  1 
ATOM   1827 N NZ  . LYS A 1 235  ? 156.864 136.772 146.415 1.00 217.64 ? 253  LYS A NZ  1 
ATOM   1828 N N   . TYR A 1 236  ? 154.966 135.188 153.042 1.00 233.81 ? 254  TYR A N   1 
ATOM   1829 C CA  . TYR A 1 236  ? 155.921 134.719 154.030 1.00 228.03 ? 254  TYR A CA  1 
ATOM   1830 C C   . TYR A 1 236  ? 157.315 135.253 153.708 1.00 223.52 ? 254  TYR A C   1 
ATOM   1831 O O   . TYR A 1 236  ? 157.582 135.768 152.618 1.00 224.09 ? 254  TYR A O   1 
ATOM   1832 C CB  . TYR A 1 236  ? 155.941 133.189 154.073 1.00 226.85 ? 254  TYR A CB  1 
ATOM   1833 C CG  . TYR A 1 236  ? 154.744 132.546 154.747 1.00 233.11 ? 254  TYR A CG  1 
ATOM   1834 C CD1 . TYR A 1 236  ? 154.393 132.866 156.053 1.00 234.95 ? 254  TYR A CD1 1 
ATOM   1835 C CD2 . TYR A 1 236  ? 153.968 131.611 154.075 1.00 235.66 ? 254  TYR A CD2 1 
ATOM   1836 C CE1 . TYR A 1 236  ? 153.305 132.278 156.665 1.00 240.88 ? 254  TYR A CE1 1 
ATOM   1837 C CE2 . TYR A 1 236  ? 152.878 131.017 154.680 1.00 237.82 ? 254  TYR A CE2 1 
ATOM   1838 C CZ  . TYR A 1 236  ? 152.550 131.355 155.975 1.00 242.88 ? 254  TYR A CZ  1 
ATOM   1839 O OH  . TYR A 1 236  ? 151.465 130.768 156.583 1.00 247.67 ? 254  TYR A OH  1 
ATOM   1840 N N   . THR A 1 237  ? 158.217 135.121 154.682 1.00 220.64 ? 255  THR A N   1 
ATOM   1841 C CA  . THR A 1 237  ? 159.597 135.551 154.483 1.00 220.67 ? 255  THR A CA  1 
ATOM   1842 C C   . THR A 1 237  ? 160.338 134.700 153.455 1.00 219.77 ? 255  THR A C   1 
ATOM   1843 O O   . THR A 1 237  ? 161.381 135.137 152.956 1.00 214.03 ? 255  THR A O   1 
ATOM   1844 C CB  . THR A 1 237  ? 160.361 135.525 155.809 1.00 219.51 ? 255  THR A CB  1 
ATOM   1845 O OG1 . THR A 1 237  ? 160.511 134.171 156.254 1.00 216.85 ? 255  THR A OG1 1 
ATOM   1846 C CG2 . THR A 1 237  ? 159.632 136.339 156.874 1.00 217.99 ? 255  THR A CG2 1 
ATOM   1847 N N   . TYR A 1 238  ? 159.826 133.511 153.125 1.00 221.04 ? 256  TYR A N   1 
ATOM   1848 C CA  . TYR A 1 238  ? 160.446 132.610 152.155 1.00 217.08 ? 256  TYR A CA  1 
ATOM   1849 C C   . TYR A 1 238  ? 159.674 132.549 150.836 1.00 216.70 ? 256  TYR A C   1 
ATOM   1850 O O   . TYR A 1 238  ? 159.985 131.709 149.986 1.00 213.13 ? 256  TYR A O   1 
ATOM   1851 C CB  . TYR A 1 238  ? 160.613 131.196 152.744 1.00 213.41 ? 256  TYR A CB  1 
ATOM   1852 C CG  . TYR A 1 238  ? 159.521 130.720 153.680 1.00 217.54 ? 256  TYR A CG  1 
ATOM   1853 C CD1 . TYR A 1 238  ? 158.335 130.197 153.187 1.00 221.61 ? 256  TYR A CD1 1 
ATOM   1854 C CD2 . TYR A 1 238  ? 159.679 130.799 155.057 1.00 220.01 ? 256  TYR A CD2 1 
ATOM   1855 C CE1 . TYR A 1 238  ? 157.339 129.761 154.039 1.00 225.67 ? 256  TYR A CE1 1 
ATOM   1856 C CE2 . TYR A 1 238  ? 158.687 130.367 155.916 1.00 223.09 ? 256  TYR A CE2 1 
ATOM   1857 C CZ  . TYR A 1 238  ? 157.519 129.850 155.402 1.00 227.33 ? 256  TYR A CZ  1 
ATOM   1858 O OH  . TYR A 1 238  ? 156.527 129.417 156.251 1.00 230.00 ? 256  TYR A OH  1 
ATOM   1859 N N   . GLY A 1 239  ? 158.688 133.428 150.638 1.00 218.21 ? 257  GLY A N   1 
ATOM   1860 C CA  . GLY A 1 239  ? 158.000 133.551 149.370 1.00 218.36 ? 257  GLY A CA  1 
ATOM   1861 C C   . GLY A 1 239  ? 156.735 132.733 149.223 1.00 221.51 ? 257  GLY A C   1 
ATOM   1862 O O   . GLY A 1 239  ? 156.028 132.901 148.222 1.00 221.61 ? 257  GLY A O   1 
ATOM   1863 N N   . LYS A 1 240  ? 156.424 131.858 150.173 1.00 222.32 ? 258  LYS A N   1 
ATOM   1864 C CA  . LYS A 1 240  ? 155.203 131.076 150.071 1.00 228.39 ? 258  LYS A CA  1 
ATOM   1865 C C   . LYS A 1 240  ? 153.990 131.977 150.328 1.00 233.85 ? 258  LYS A C   1 
ATOM   1866 O O   . LYS A 1 240  ? 154.037 132.826 151.223 1.00 233.47 ? 258  LYS A O   1 
ATOM   1867 C CB  . LYS A 1 240  ? 155.229 129.921 151.073 1.00 229.04 ? 258  LYS A CB  1 
ATOM   1868 C CG  . LYS A 1 240  ? 153.891 129.204 151.269 1.00 231.63 ? 258  LYS A CG  1 
ATOM   1869 C CD  . LYS A 1 240  ? 154.054 127.820 151.901 1.00 227.02 ? 258  LYS A CD  1 
ATOM   1870 C CE  . LYS A 1 240  ? 154.169 127.899 153.416 1.00 225.44 ? 258  LYS A CE  1 
ATOM   1871 N NZ  . LYS A 1 240  ? 155.160 126.928 153.954 1.00 219.99 ? 258  LYS A NZ  1 
ATOM   1872 N N   . PRO A 1 241  ? 152.897 131.835 149.568 1.00 237.73 ? 259  PRO A N   1 
ATOM   1873 C CA  . PRO A 1 241  ? 151.712 132.652 149.860 1.00 240.20 ? 259  PRO A CA  1 
ATOM   1874 C C   . PRO A 1 241  ? 151.088 132.298 151.201 1.00 242.10 ? 259  PRO A C   1 
ATOM   1875 O O   . PRO A 1 241  ? 151.197 131.170 151.689 1.00 241.41 ? 259  PRO A O   1 
ATOM   1876 C CB  . PRO A 1 241  ? 150.757 132.335 148.703 1.00 243.56 ? 259  PRO A CB  1 
ATOM   1877 C CG  . PRO A 1 241  ? 151.228 131.055 148.148 1.00 241.06 ? 259  PRO A CG  1 
ATOM   1878 C CD  . PRO A 1 241  ? 152.706 131.070 148.320 1.00 236.75 ? 259  PRO A CD  1 
ATOM   1879 N N   . VAL A 1 242  ? 150.422 133.289 151.790 1.00 244.13 ? 260  VAL A N   1 
ATOM   1880 C CA  . VAL A 1 242  ? 149.796 133.181 153.104 1.00 246.34 ? 260  VAL A CA  1 
ATOM   1881 C C   . VAL A 1 242  ? 148.289 133.098 152.908 1.00 251.76 ? 260  VAL A C   1 
ATOM   1882 O O   . VAL A 1 242  ? 147.696 133.945 152.228 1.00 253.87 ? 260  VAL A O   1 
ATOM   1883 C CB  . VAL A 1 242  ? 150.156 134.375 154.004 1.00 243.55 ? 260  VAL A CB  1 
ATOM   1884 C CG1 . VAL A 1 242  ? 149.569 134.189 155.404 1.00 247.13 ? 260  VAL A CG1 1 
ATOM   1885 C CG2 . VAL A 1 242  ? 151.667 134.573 154.068 1.00 239.53 ? 260  VAL A CG2 1 
ATOM   1886 N N   . LYS A 1 243  ? 147.672 132.081 153.508 1.00 253.15 ? 261  LYS A N   1 
ATOM   1887 C CA  . LYS A 1 243  ? 146.221 131.965 153.568 1.00 255.31 ? 261  LYS A CA  1 
ATOM   1888 C C   . LYS A 1 243  ? 145.719 132.555 154.880 1.00 257.38 ? 261  LYS A C   1 
ATOM   1889 O O   . LYS A 1 243  ? 146.264 132.267 155.950 1.00 255.37 ? 261  LYS A O   1 
ATOM   1890 C CB  . LYS A 1 243  ? 145.793 130.501 153.450 1.00 253.85 ? 261  LYS A CB  1 
ATOM   1891 C CG  . LYS A 1 243  ? 144.305 130.286 153.182 1.00 255.60 ? 261  LYS A CG  1 
ATOM   1892 C CD  . LYS A 1 243  ? 143.956 130.480 151.715 1.00 256.40 ? 261  LYS A CD  1 
ATOM   1893 C CE  . LYS A 1 243  ? 142.465 130.710 151.527 1.00 256.09 ? 261  LYS A CE  1 
ATOM   1894 N NZ  . LYS A 1 243  ? 142.050 132.091 151.900 1.00 255.58 ? 261  LYS A NZ  1 
ATOM   1895 N N   . GLY A 1 244  ? 144.681 133.377 154.798 1.00 259.57 ? 262  GLY A N   1 
ATOM   1896 C CA  . GLY A 1 244  ? 144.150 133.992 156.000 1.00 261.57 ? 262  GLY A CA  1 
ATOM   1897 C C   . GLY A 1 244  ? 142.948 134.862 155.717 1.00 261.63 ? 262  GLY A C   1 
ATOM   1898 O O   . GLY A 1 244  ? 142.364 134.810 154.633 1.00 260.78 ? 262  GLY A O   1 
ATOM   1899 N N   . ASP A 1 245  ? 142.586 135.667 156.718 1.00 264.66 ? 263  ASP A N   1 
ATOM   1900 C CA  . ASP A 1 245  ? 141.435 136.558 156.668 1.00 267.05 ? 263  ASP A CA  1 
ATOM   1901 C C   . ASP A 1 245  ? 141.899 137.998 156.828 1.00 268.93 ? 263  ASP A C   1 
ATOM   1902 O O   . ASP A 1 245  ? 142.705 138.308 157.712 1.00 268.25 ? 263  ASP A O   1 
ATOM   1903 C CB  . ASP A 1 245  ? 140.424 136.205 157.768 1.00 267.74 ? 263  ASP A CB  1 
ATOM   1904 C CG  . ASP A 1 245  ? 139.528 137.373 158.141 1.00 266.53 ? 263  ASP A CG  1 
ATOM   1905 O OD1 . ASP A 1 245  ? 138.944 138.000 157.232 1.00 266.73 ? 263  ASP A OD1 1 
ATOM   1906 O OD2 . ASP A 1 245  ? 139.406 137.664 159.350 1.00 263.86 ? 263  ASP A OD2 1 
ATOM   1907 N N   . VAL A 1 246  ? 141.375 138.874 155.973 1.00 269.09 ? 264  VAL A N   1 
ATOM   1908 C CA  . VAL A 1 246  ? 141.708 140.291 155.951 1.00 268.13 ? 264  VAL A CA  1 
ATOM   1909 C C   . VAL A 1 246  ? 140.478 141.098 156.341 1.00 266.81 ? 264  VAL A C   1 
ATOM   1910 O O   . VAL A 1 246  ? 139.357 140.805 155.902 1.00 265.90 ? 264  VAL A O   1 
ATOM   1911 C CB  . VAL A 1 246  ? 142.240 140.722 154.568 1.00 266.06 ? 264  VAL A CB  1 
ATOM   1912 C CG1 . VAL A 1 246  ? 143.286 139.746 154.094 1.00 264.39 ? 264  VAL A CG1 1 
ATOM   1913 C CG2 . VAL A 1 246  ? 141.106 140.799 153.544 1.00 263.76 ? 264  VAL A CG2 1 
ATOM   1914 N N   . THR A 1 247  ? 140.696 142.093 157.200 1.00 266.02 ? 265  THR A N   1 
ATOM   1915 C CA  . THR A 1 247  ? 139.702 143.102 157.544 1.00 265.05 ? 265  THR A CA  1 
ATOM   1916 C C   . THR A 1 247  ? 140.237 144.453 157.093 1.00 263.33 ? 265  THR A C   1 
ATOM   1917 O O   . THR A 1 247  ? 141.304 144.883 157.547 1.00 262.62 ? 265  THR A O   1 
ATOM   1918 C CB  . THR A 1 247  ? 139.415 143.108 159.048 1.00 263.64 ? 265  THR A CB  1 
ATOM   1919 O OG1 . THR A 1 247  ? 138.928 141.822 159.450 1.00 265.28 ? 265  THR A OG1 1 
ATOM   1920 C CG2 . THR A 1 247  ? 138.376 144.169 159.394 1.00 259.95 ? 265  THR A CG2 1 
ATOM   1921 N N   . LEU A 1 248  ? 139.499 145.115 156.207 1.00 261.95 ? 266  LEU A N   1 
ATOM   1922 C CA  . LEU A 1 248  ? 139.887 146.390 155.620 1.00 261.29 ? 266  LEU A CA  1 
ATOM   1923 C C   . LEU A 1 248  ? 138.992 147.479 156.192 1.00 261.82 ? 266  LEU A C   1 
ATOM   1924 O O   . LEU A 1 248  ? 137.766 147.417 156.049 1.00 260.27 ? 266  LEU A O   1 
ATOM   1925 C CB  . LEU A 1 248  ? 139.769 146.339 154.096 1.00 259.48 ? 266  LEU A CB  1 
ATOM   1926 C CG  . LEU A 1 248  ? 140.565 147.357 153.274 1.00 259.11 ? 266  LEU A CG  1 
ATOM   1927 C CD1 . LEU A 1 248  ? 142.068 147.168 153.438 1.00 262.42 ? 266  LEU A CD1 1 
ATOM   1928 C CD2 . LEU A 1 248  ? 140.179 147.257 151.806 1.00 253.73 ? 266  LEU A CD2 1 
ATOM   1929 N N   . THR A 1 249  ? 139.612 148.466 156.836 1.00 264.92 ? 267  THR A N   1 
ATOM   1930 C CA  . THR A 1 249  ? 138.931 149.607 157.432 1.00 267.98 ? 267  THR A CA  1 
ATOM   1931 C C   . THR A 1 249  ? 139.317 150.855 156.651 1.00 270.88 ? 267  THR A C   1 
ATOM   1932 O O   . THR A 1 249  ? 140.490 151.246 156.640 1.00 271.68 ? 267  THR A O   1 
ATOM   1933 C CB  . THR A 1 249  ? 139.305 149.760 158.907 1.00 267.08 ? 267  THR A CB  1 
ATOM   1934 O OG1 . THR A 1 249  ? 139.024 148.539 159.603 1.00 261.63 ? 267  THR A OG1 1 
ATOM   1935 C CG2 . THR A 1 249  ? 138.522 150.900 159.550 1.00 267.96 ? 267  THR A CG2 1 
ATOM   1936 N N   . PHE A 1 250  ? 138.332 151.467 155.998 1.00 271.57 ? 268  PHE A N   1 
ATOM   1937 C CA  . PHE A 1 250  ? 138.507 152.703 155.245 1.00 273.17 ? 268  PHE A CA  1 
ATOM   1938 C C   . PHE A 1 250  ? 137.862 153.833 156.035 1.00 275.49 ? 268  PHE A C   1 
ATOM   1939 O O   . PHE A 1 250  ? 136.654 153.795 156.293 1.00 274.77 ? 268  PHE A O   1 
ATOM   1940 C CB  . PHE A 1 250  ? 137.885 152.579 153.854 1.00 269.53 ? 268  PHE A CB  1 
ATOM   1941 C CG  . PHE A 1 250  ? 137.470 153.889 153.253 1.00 268.85 ? 268  PHE A CG  1 
ATOM   1942 C CD1 . PHE A 1 250  ? 138.416 154.812 152.846 1.00 269.27 ? 268  PHE A CD1 1 
ATOM   1943 C CD2 . PHE A 1 250  ? 136.130 154.192 153.085 1.00 267.93 ? 268  PHE A CD2 1 
ATOM   1944 C CE1 . PHE A 1 250  ? 138.032 156.015 152.290 1.00 270.06 ? 268  PHE A CE1 1 
ATOM   1945 C CE2 . PHE A 1 250  ? 135.741 155.392 152.529 1.00 268.45 ? 268  PHE A CE2 1 
ATOM   1946 C CZ  . PHE A 1 250  ? 136.694 156.305 152.131 1.00 270.25 ? 268  PHE A CZ  1 
ATOM   1947 N N   . LEU A 1 251  ? 138.667 154.831 156.413 1.00 278.14 ? 269  LEU A N   1 
ATOM   1948 C CA  . LEU A 1 251  ? 138.257 155.890 157.325 1.00 280.22 ? 269  LEU A CA  1 
ATOM   1949 C C   . LEU A 1 251  ? 138.642 157.245 156.738 1.00 281.10 ? 269  LEU A C   1 
ATOM   1950 O O   . LEU A 1 251  ? 139.826 157.457 156.417 1.00 279.52 ? 269  LEU A O   1 
ATOM   1951 C CB  . LEU A 1 251  ? 138.925 155.695 158.695 1.00 277.95 ? 269  LEU A CB  1 
ATOM   1952 C CG  . LEU A 1 251  ? 138.707 156.764 159.771 1.00 276.77 ? 269  LEU A CG  1 
ATOM   1953 C CD1 . LEU A 1 251  ? 137.228 157.025 160.015 1.00 278.20 ? 269  LEU A CD1 1 
ATOM   1954 C CD2 . LEU A 1 251  ? 139.397 156.344 161.060 1.00 271.63 ? 269  LEU A CD2 1 
ATOM   1955 N N   . PRO A 1 252  ? 137.709 158.192 156.575 1.00 283.73 ? 270  PRO A N   1 
ATOM   1956 C CA  . PRO A 1 252  ? 138.138 159.549 156.217 1.00 284.85 ? 270  PRO A CA  1 
ATOM   1957 C C   . PRO A 1 252  ? 138.907 160.194 157.357 1.00 286.41 ? 270  PRO A C   1 
ATOM   1958 O O   . PRO A 1 252  ? 138.636 159.941 158.534 1.00 285.85 ? 270  PRO A O   1 
ATOM   1959 C CB  . PRO A 1 252  ? 136.823 160.286 155.937 1.00 284.38 ? 270  PRO A CB  1 
ATOM   1960 C CG  . PRO A 1 252  ? 135.796 159.523 156.653 1.00 280.85 ? 270  PRO A CG  1 
ATOM   1961 C CD  . PRO A 1 252  ? 136.234 158.098 156.589 1.00 281.70 ? 270  PRO A CD  1 
ATOM   1962 N N   . LEU A 1 253  ? 139.871 161.037 156.996 1.00 287.48 ? 271  LEU A N   1 
ATOM   1963 C CA  . LEU A 1 253  ? 140.658 161.793 157.961 1.00 290.94 ? 271  LEU A CA  1 
ATOM   1964 C C   . LEU A 1 253  ? 140.065 163.168 158.254 1.00 296.86 ? 271  LEU A C   1 
ATOM   1965 O O   . LEU A 1 253  ? 140.754 164.016 158.829 1.00 300.76 ? 271  LEU A O   1 
ATOM   1966 C CB  . LEU A 1 253  ? 142.100 161.939 157.464 1.00 286.40 ? 271  LEU A CB  1 
ATOM   1967 C CG  . LEU A 1 253  ? 142.888 160.631 157.315 1.00 279.28 ? 271  LEU A CG  1 
ATOM   1968 C CD1 . LEU A 1 253  ? 144.218 160.871 156.617 1.00 272.40 ? 271  LEU A CD1 1 
ATOM   1969 C CD2 . LEU A 1 253  ? 143.115 159.970 158.669 1.00 277.26 ? 271  LEU A CD2 1 
ATOM   1970 N N   . SER A 1 254  ? 138.811 163.413 157.871 1.00 297.60 ? 272  SER A N   1 
ATOM   1971 C CA  . SER A 1 254  ? 138.144 164.653 158.246 1.00 298.30 ? 272  SER A CA  1 
ATOM   1972 C C   . SER A 1 254  ? 137.751 164.581 159.717 1.00 300.20 ? 272  SER A C   1 
ATOM   1973 O O   . SER A 1 254  ? 136.634 164.172 160.050 1.00 298.23 ? 272  SER A O   1 
ATOM   1974 C CB  . SER A 1 254  ? 136.916 164.895 157.364 1.00 291.68 ? 272  SER A CB  1 
ATOM   1975 O OG  . SER A 1 254  ? 136.116 165.949 157.872 1.00 289.93 ? 272  SER A OG  1 
ATOM   1976 N N   . PHE A 1 255  ? 138.665 164.986 160.601 1.00 301.85 ? 273  PHE A N   1 
ATOM   1977 C CA  . PHE A 1 255  ? 138.457 164.865 162.041 1.00 297.15 ? 273  PHE A CA  1 
ATOM   1978 C C   . PHE A 1 255  ? 137.403 165.825 162.578 1.00 299.43 ? 273  PHE A C   1 
ATOM   1979 O O   . PHE A 1 255  ? 136.963 165.653 163.720 1.00 295.99 ? 273  PHE A O   1 
ATOM   1980 C CB  . PHE A 1 255  ? 139.774 165.092 162.812 1.00 293.75 ? 273  PHE A CB  1 
ATOM   1981 C CG  . PHE A 1 255  ? 140.846 164.020 162.611 1.00 291.65 ? 273  PHE A CG  1 
ATOM   1982 C CD1 . PHE A 1 255  ? 140.726 162.995 161.674 1.00 291.53 ? 273  PHE A CD1 1 
ATOM   1983 C CD2 . PHE A 1 255  ? 141.973 164.027 163.419 1.00 289.51 ? 273  PHE A CD2 1 
ATOM   1984 C CE1 . PHE A 1 255  ? 141.710 162.038 161.528 1.00 288.35 ? 273  PHE A CE1 1 
ATOM   1985 C CE2 . PHE A 1 255  ? 142.962 163.067 163.272 1.00 287.57 ? 273  PHE A CE2 1 
ATOM   1986 C CZ  . PHE A 1 255  ? 142.823 162.073 162.327 1.00 286.89 ? 273  PHE A CZ  1 
ATOM   1987 N N   . TRP A 1 256  ? 136.984 166.822 161.797 1.00 303.39 ? 274  TRP A N   1 
ATOM   1988 C CA  . TRP A 1 256  ? 135.924 167.710 162.261 1.00 302.96 ? 274  TRP A CA  1 
ATOM   1989 C C   . TRP A 1 256  ? 134.596 166.970 162.359 1.00 300.66 ? 274  TRP A C   1 
ATOM   1990 O O   . TRP A 1 256  ? 133.815 167.207 163.288 1.00 297.58 ? 274  TRP A O   1 
ATOM   1991 C CB  . TRP A 1 256  ? 135.798 168.916 161.331 1.00 302.55 ? 274  TRP A CB  1 
ATOM   1992 C CG  . TRP A 1 256  ? 137.088 169.650 161.106 1.00 303.47 ? 274  TRP A CG  1 
ATOM   1993 C CD1 . TRP A 1 256  ? 137.862 169.622 159.985 1.00 301.88 ? 274  TRP A CD1 1 
ATOM   1994 C CD2 . TRP A 1 256  ? 137.749 170.524 162.028 1.00 304.16 ? 274  TRP A CD2 1 
ATOM   1995 N NE1 . TRP A 1 256  ? 138.966 170.422 160.151 1.00 301.70 ? 274  TRP A NE1 1 
ATOM   1996 C CE2 . TRP A 1 256  ? 138.920 170.988 161.397 1.00 303.05 ? 274  TRP A CE2 1 
ATOM   1997 C CE3 . TRP A 1 256  ? 137.464 170.959 163.326 1.00 303.01 ? 274  TRP A CE3 1 
ATOM   1998 C CZ2 . TRP A 1 256  ? 139.805 171.864 162.020 1.00 302.25 ? 274  TRP A CZ2 1 
ATOM   1999 C CZ3 . TRP A 1 256  ? 138.344 171.829 163.942 1.00 301.33 ? 274  TRP A CZ3 1 
ATOM   2000 C CH2 . TRP A 1 256  ? 139.501 172.272 163.289 1.00 301.81 ? 274  TRP A CH2 1 
ATOM   2001 N N   . GLY A 1 257  ? 134.329 166.069 161.418 1.00 299.45 ? 275  GLY A N   1 
ATOM   2002 C CA  . GLY A 1 257  ? 133.095 165.313 161.386 1.00 294.47 ? 275  GLY A CA  1 
ATOM   2003 C C   . GLY A 1 257  ? 133.187 164.024 162.173 1.00 291.38 ? 275  GLY A C   1 
ATOM   2004 O O   . GLY A 1 257  ? 133.927 163.909 163.153 1.00 290.50 ? 275  GLY A O   1 
ATOM   2005 N N   . LYS A 1 258  ? 132.415 163.037 161.727 1.00 287.80 ? 276  LYS A N   1 
ATOM   2006 C CA  . LYS A 1 258  ? 132.346 161.752 162.402 1.00 283.62 ? 276  LYS A CA  1 
ATOM   2007 C C   . LYS A 1 258  ? 133.480 160.841 161.938 1.00 283.71 ? 276  LYS A C   1 
ATOM   2008 O O   . LYS A 1 258  ? 134.075 161.037 160.874 1.00 283.76 ? 276  LYS A O   1 
ATOM   2009 C CB  . LYS A 1 258  ? 130.997 161.069 162.147 1.00 277.84 ? 276  LYS A CB  1 
ATOM   2010 C CG  . LYS A 1 258  ? 129.770 161.988 162.190 1.00 271.58 ? 276  LYS A CG  1 
ATOM   2011 C CD  . LYS A 1 258  ? 128.496 161.224 161.861 1.00 261.98 ? 276  LYS A CD  1 
ATOM   2012 C CE  . LYS A 1 258  ? 127.367 162.166 161.466 1.00 253.60 ? 276  LYS A CE  1 
ATOM   2013 N NZ  . LYS A 1 258  ? 126.139 161.430 161.057 1.00 249.49 ? 276  LYS A NZ  1 
ATOM   2014 N N   . LYS A 1 259  ? 133.770 159.832 162.759 1.00 282.58 ? 277  LYS A N   1 
ATOM   2015 C CA  . LYS A 1 259  ? 134.793 158.829 162.477 1.00 279.79 ? 277  LYS A CA  1 
ATOM   2016 C C   . LYS A 1 259  ? 134.170 157.517 162.005 1.00 279.57 ? 277  LYS A C   1 
ATOM   2017 O O   . LYS A 1 259  ? 134.696 156.432 162.261 1.00 274.75 ? 277  LYS A O   1 
ATOM   2018 C CB  . LYS A 1 259  ? 135.666 158.591 163.709 1.00 273.74 ? 277  LYS A CB  1 
ATOM   2019 C CG  . LYS A 1 259  ? 136.423 159.822 164.259 1.00 269.66 ? 277  LYS A CG  1 
ATOM   2020 C CD  . LYS A 1 259  ? 137.164 160.667 163.207 1.00 273.10 ? 277  LYS A CD  1 
ATOM   2021 C CE  . LYS A 1 259  ? 138.359 159.936 162.604 1.00 275.19 ? 277  LYS A CE  1 
ATOM   2022 N NZ  . LYS A 1 259  ? 138.628 160.383 161.209 1.00 281.00 ? 277  LYS A NZ  1 
ATOM   2023 N N   . LYS A 1 260  ? 133.033 157.606 161.318 1.00 282.93 ? 278  LYS A N   1 
ATOM   2024 C CA  . LYS A 1 260  ? 132.442 156.433 160.684 1.00 279.63 ? 278  LYS A CA  1 
ATOM   2025 C C   . LYS A 1 260  ? 133.398 155.865 159.642 1.00 277.95 ? 278  LYS A C   1 
ATOM   2026 O O   . LYS A 1 260  ? 134.084 156.609 158.935 1.00 279.12 ? 278  LYS A O   1 
ATOM   2027 C CB  . LYS A 1 260  ? 131.098 156.776 160.027 1.00 277.40 ? 278  LYS A CB  1 
ATOM   2028 C CG  . LYS A 1 260  ? 131.074 158.041 159.157 1.00 274.55 ? 278  LYS A CG  1 
ATOM   2029 C CD  . LYS A 1 260  ? 129.702 158.277 158.546 1.00 270.00 ? 278  LYS A CD  1 
ATOM   2030 C CE  . LYS A 1 260  ? 129.582 159.692 158.000 1.00 271.58 ? 278  LYS A CE  1 
ATOM   2031 N NZ  . LYS A 1 260  ? 128.254 159.951 157.380 1.00 274.95 ? 278  LYS A NZ  1 
ATOM   2032 N N   . ASN A 1 261  ? 133.441 154.535 159.555 1.00 275.71 ? 279  ASN A N   1 
ATOM   2033 C CA  . ASN A 1 261  ? 134.372 153.824 158.690 1.00 273.44 ? 279  ASN A CA  1 
ATOM   2034 C C   . ASN A 1 261  ? 133.652 152.699 157.961 1.00 269.04 ? 279  ASN A C   1 
ATOM   2035 O O   . ASN A 1 261  ? 132.618 152.198 158.409 1.00 267.47 ? 279  ASN A O   1 
ATOM   2036 C CB  . ASN A 1 261  ? 135.548 153.248 159.490 1.00 271.15 ? 279  ASN A CB  1 
ATOM   2037 C CG  . ASN A 1 261  ? 135.095 152.375 160.644 1.00 263.48 ? 279  ASN A CG  1 
ATOM   2038 O OD1 . ASN A 1 261  ? 134.840 151.183 160.472 1.00 259.32 ? 279  ASN A OD1 1 
ATOM   2039 N ND2 . ASN A 1 261  ? 134.990 152.967 161.828 1.00 259.66 ? 279  ASN A ND2 1 
ATOM   2040 N N   . ILE A 1 262  ? 134.225 152.309 156.824 1.00 268.14 ? 280  ILE A N   1 
ATOM   2041 C CA  . ILE A 1 262  ? 133.731 151.200 156.014 1.00 264.97 ? 280  ILE A CA  1 
ATOM   2042 C C   . ILE A 1 262  ? 134.580 149.979 156.336 1.00 262.89 ? 280  ILE A C   1 
ATOM   2043 O O   . ILE A 1 262  ? 135.811 150.026 156.224 1.00 263.16 ? 280  ILE A O   1 
ATOM   2044 C CB  . ILE A 1 262  ? 133.791 151.528 154.513 1.00 264.06 ? 280  ILE A CB  1 
ATOM   2045 C CG1 . ILE A 1 262  ? 132.850 152.693 154.155 1.00 264.36 ? 280  ILE A CG1 1 
ATOM   2046 C CG2 . ILE A 1 262  ? 133.481 150.285 153.676 1.00 257.81 ? 280  ILE A CG2 1 
ATOM   2047 C CD1 . ILE A 1 262  ? 131.352 152.422 154.326 1.00 264.07 ? 280  ILE A CD1 1 
ATOM   2048 N N   . THR A 1 263  ? 133.922 148.890 156.728 1.00 259.98 ? 281  THR A N   1 
ATOM   2049 C CA  . THR A 1 263  ? 134.575 147.638 157.091 1.00 257.65 ? 281  THR A CA  1 
ATOM   2050 C C   . THR A 1 263  ? 134.270 146.584 156.036 1.00 256.92 ? 281  THR A C   1 
ATOM   2051 O O   . THR A 1 263  ? 133.109 146.399 155.657 1.00 255.64 ? 281  THR A O   1 
ATOM   2052 C CB  . THR A 1 263  ? 134.104 147.154 158.465 1.00 254.36 ? 281  THR A CB  1 
ATOM   2053 O OG1 . THR A 1 263  ? 133.894 148.280 159.327 1.00 252.76 ? 281  THR A OG1 1 
ATOM   2054 C CG2 . THR A 1 263  ? 135.137 146.226 159.088 1.00 252.97 ? 281  THR A CG2 1 
ATOM   2055 N N   . LYS A 1 264  ? 135.315 145.903 155.564 1.00 256.78 ? 282  LYS A N   1 
ATOM   2056 C CA  . LYS A 1 264  ? 135.187 144.822 154.586 1.00 256.28 ? 282  LYS A CA  1 
ATOM   2057 C C   . LYS A 1 264  ? 136.029 143.645 155.056 1.00 259.34 ? 282  LYS A C   1 
ATOM   2058 O O   . LYS A 1 264  ? 137.259 143.738 155.092 1.00 260.21 ? 282  LYS A O   1 
ATOM   2059 C CB  . LYS A 1 264  ? 135.630 145.278 153.196 1.00 252.55 ? 282  LYS A CB  1 
ATOM   2060 C CG  . LYS A 1 264  ? 134.566 146.019 152.405 1.00 248.08 ? 282  LYS A CG  1 
ATOM   2061 C CD  . LYS A 1 264  ? 134.917 146.059 150.927 1.00 243.71 ? 282  LYS A CD  1 
ATOM   2062 C CE  . LYS A 1 264  ? 133.867 146.803 150.121 1.00 244.23 ? 282  LYS A CE  1 
ATOM   2063 N NZ  . LYS A 1 264  ? 134.198 146.840 148.669 1.00 247.07 ? 282  LYS A NZ  1 
ATOM   2064 N N   . THR A 1 265  ? 135.372 142.541 155.406 1.00 262.76 ? 283  THR A N   1 
ATOM   2065 C CA  . THR A 1 265  ? 136.034 141.332 155.885 1.00 266.23 ? 283  THR A CA  1 
ATOM   2066 C C   . THR A 1 265  ? 135.908 140.248 154.823 1.00 266.56 ? 283  THR A C   1 
ATOM   2067 O O   . THR A 1 265  ? 134.797 139.936 154.382 1.00 267.52 ? 283  THR A O   1 
ATOM   2068 C CB  . THR A 1 265  ? 135.424 140.861 157.205 1.00 267.35 ? 283  THR A CB  1 
ATOM   2069 O OG1 . THR A 1 265  ? 134.011 140.674 157.045 1.00 269.65 ? 283  THR A OG1 1 
ATOM   2070 C CG2 . THR A 1 265  ? 135.679 141.880 158.306 1.00 264.56 ? 283  THR A CG2 1 
ATOM   2071 N N   . PHE A 1 266  ? 137.040 139.680 154.414 1.00 264.90 ? 284  PHE A N   1 
ATOM   2072 C CA  . PHE A 1 266  ? 137.028 138.587 153.443 1.00 262.16 ? 284  PHE A CA  1 
ATOM   2073 C C   . PHE A 1 266  ? 138.332 137.807 153.582 1.00 263.00 ? 284  PHE A C   1 
ATOM   2074 O O   . PHE A 1 266  ? 139.079 137.993 154.544 1.00 263.84 ? 284  PHE A O   1 
ATOM   2075 C CB  . PHE A 1 266  ? 136.773 139.127 152.028 1.00 259.09 ? 284  PHE A CB  1 
ATOM   2076 C CG  . PHE A 1 266  ? 137.835 140.060 151.521 1.00 259.22 ? 284  PHE A CG  1 
ATOM   2077 C CD1 . PHE A 1 266  ? 137.800 141.408 151.839 1.00 258.73 ? 284  PHE A CD1 1 
ATOM   2078 C CD2 . PHE A 1 266  ? 138.852 139.597 150.705 1.00 257.95 ? 284  PHE A CD2 1 
ATOM   2079 C CE1 . PHE A 1 266  ? 138.767 142.271 151.366 1.00 256.71 ? 284  PHE A CE1 1 
ATOM   2080 C CE2 . PHE A 1 266  ? 139.821 140.458 150.230 1.00 256.15 ? 284  PHE A CE2 1 
ATOM   2081 C CZ  . PHE A 1 266  ? 139.779 141.797 150.561 1.00 255.07 ? 284  PHE A CZ  1 
ATOM   2082 N N   . LYS A 1 267  ? 138.590 136.904 152.636 1.00 261.92 ? 285  LYS A N   1 
ATOM   2083 C CA  . LYS A 1 267  ? 139.702 135.964 152.707 1.00 261.21 ? 285  LYS A CA  1 
ATOM   2084 C C   . LYS A 1 267  ? 140.776 136.313 151.684 1.00 259.68 ? 285  LYS A C   1 
ATOM   2085 O O   . LYS A 1 267  ? 140.521 136.987 150.682 1.00 257.20 ? 285  LYS A O   1 
ATOM   2086 C CB  . LYS A 1 267  ? 139.219 134.526 152.477 1.00 259.91 ? 285  LYS A CB  1 
ATOM   2087 C CG  . LYS A 1 267  ? 138.144 134.037 153.457 1.00 258.73 ? 285  LYS A CG  1 
ATOM   2088 C CD  . LYS A 1 267  ? 138.662 133.852 154.886 1.00 259.25 ? 285  LYS A CD  1 
ATOM   2089 C CE  . LYS A 1 267  ? 139.554 132.626 155.025 1.00 258.95 ? 285  LYS A CE  1 
ATOM   2090 N NZ  . LYS A 1 267  ? 139.984 132.416 156.435 1.00 259.53 ? 285  LYS A NZ  1 
ATOM   2091 N N   . ILE A 1 268  ? 141.993 135.840 151.959 1.00 259.72 ? 286  ILE A N   1 
ATOM   2092 C CA  . ILE A 1 268  ? 143.156 136.058 151.107 1.00 257.72 ? 286  ILE A CA  1 
ATOM   2093 C C   . ILE A 1 268  ? 143.934 134.754 151.011 1.00 257.69 ? 286  ILE A C   1 
ATOM   2094 O O   . ILE A 1 268  ? 144.060 134.023 152.001 1.00 257.60 ? 286  ILE A O   1 
ATOM   2095 C CB  . ILE A 1 268  ? 144.067 137.188 151.642 1.00 256.73 ? 286  ILE A CB  1 
ATOM   2096 C CG1 . ILE A 1 268  ? 145.273 137.394 150.718 1.00 255.03 ? 286  ILE A CG1 1 
ATOM   2097 C CG2 . ILE A 1 268  ? 144.563 136.878 153.067 1.00 259.10 ? 286  ILE A CG2 1 
ATOM   2098 C CD1 . ILE A 1 268  ? 145.996 138.707 150.938 1.00 253.91 ? 286  ILE A CD1 1 
ATOM   2099 N N   . ASN A 1 269  ? 144.454 134.471 149.818 1.00 257.86 ? 287  ASN A N   1 
ATOM   2100 C CA  . ASN A 1 269  ? 145.396 133.380 149.572 1.00 259.91 ? 287  ASN A CA  1 
ATOM   2101 C C   . ASN A 1 269  ? 146.612 133.986 148.879 1.00 259.37 ? 287  ASN A C   1 
ATOM   2102 O O   . ASN A 1 269  ? 146.691 134.030 147.649 1.00 259.93 ? 287  ASN A O   1 
ATOM   2103 C CB  . ASN A 1 269  ? 144.757 132.270 148.733 1.00 260.95 ? 287  ASN A CB  1 
ATOM   2104 C CG  . ASN A 1 269  ? 145.617 131.022 148.666 1.00 261.87 ? 287  ASN A CG  1 
ATOM   2105 O OD1 . ASN A 1 269  ? 146.641 130.922 149.343 1.00 259.93 ? 287  ASN A OD1 1 
ATOM   2106 N ND2 . ASN A 1 269  ? 145.206 130.064 147.844 1.00 261.53 ? 287  ASN A ND2 1 
ATOM   2107 N N   . GLY A 1 270  ? 147.564 134.459 149.679 1.00 256.98 ? 288  GLY A N   1 
ATOM   2108 C CA  . GLY A 1 270  ? 148.747 135.103 149.143 1.00 253.90 ? 288  GLY A CA  1 
ATOM   2109 C C   . GLY A 1 270  ? 148.481 136.530 148.720 1.00 254.60 ? 288  GLY A C   1 
ATOM   2110 O O   . GLY A 1 270  ? 148.981 137.472 149.343 1.00 253.43 ? 288  GLY A O   1 
ATOM   2111 N N   . SER A 1 271  ? 147.696 136.695 147.656 1.00 257.04 ? 289  SER A N   1 
ATOM   2112 C CA  . SER A 1 271  ? 147.307 138.000 147.143 1.00 256.37 ? 289  SER A CA  1 
ATOM   2113 C C   . SER A 1 271  ? 145.801 138.032 146.932 1.00 252.95 ? 289  SER A C   1 
ATOM   2114 O O   . SER A 1 271  ? 145.185 137.020 146.586 1.00 252.95 ? 289  SER A O   1 
ATOM   2115 C CB  . SER A 1 271  ? 148.017 138.322 145.824 1.00 257.77 ? 289  SER A CB  1 
ATOM   2116 O OG  . SER A 1 271  ? 149.414 138.456 146.015 1.00 257.73 ? 289  SER A OG  1 
ATOM   2117 N N   . ALA A 1 272  ? 145.214 139.207 147.153 1.00 250.90 ? 290  ALA A N   1 
ATOM   2118 C CA  . ALA A 1 272  ? 143.797 139.412 146.887 1.00 248.63 ? 290  ALA A CA  1 
ATOM   2119 C C   . ALA A 1 272  ? 143.575 140.847 146.436 1.00 247.85 ? 290  ALA A C   1 
ATOM   2120 O O   . ALA A 1 272  ? 144.111 141.786 147.037 1.00 250.82 ? 290  ALA A O   1 
ATOM   2121 C CB  . ALA A 1 272  ? 142.939 139.099 148.119 1.00 247.69 ? 290  ALA A CB  1 
ATOM   2122 N N   . ASN A 1 273  ? 142.789 141.002 145.374 1.00 243.46 ? 291  ASN A N   1 
ATOM   2123 C CA  . ASN A 1 273  ? 142.432 142.299 144.821 1.00 241.21 ? 291  ASN A CA  1 
ATOM   2124 C C   . ASN A 1 273  ? 141.065 142.718 145.342 1.00 238.46 ? 291  ASN A C   1 
ATOM   2125 O O   . ASN A 1 273  ? 140.146 141.898 145.428 1.00 236.23 ? 291  ASN A O   1 
ATOM   2126 C CB  . ASN A 1 273  ? 142.409 142.244 143.293 1.00 237.82 ? 291  ASN A CB  1 
ATOM   2127 C CG  . ASN A 1 273  ? 143.690 141.683 142.712 1.00 234.49 ? 291  ASN A CG  1 
ATOM   2128 O OD1 . ASN A 1 273  ? 144.594 141.284 143.446 1.00 240.20 ? 291  ASN A OD1 1 
ATOM   2129 N ND2 . ASN A 1 273  ? 143.768 141.633 141.388 1.00 217.49 ? 291  ASN A ND2 1 
ATOM   2130 N N   . PHE A 1 274  ? 140.940 143.997 145.696 1.00 240.71 ? 292  PHE A N   1 
ATOM   2131 C CA  . PHE A 1 274  ? 139.675 144.584 146.108 1.00 241.18 ? 292  PHE A CA  1 
ATOM   2132 C C   . PHE A 1 274  ? 139.411 145.835 145.284 1.00 243.64 ? 292  PHE A C   1 
ATOM   2133 O O   . PHE A 1 274  ? 140.340 146.484 144.795 1.00 244.09 ? 292  PHE A O   1 
ATOM   2134 C CB  . PHE A 1 274  ? 139.663 144.920 147.610 1.00 241.33 ? 292  PHE A CB  1 
ATOM   2135 C CG  . PHE A 1 274  ? 140.686 145.942 148.018 1.00 244.26 ? 292  PHE A CG  1 
ATOM   2136 C CD1 . PHE A 1 274  ? 141.986 145.561 148.303 1.00 246.75 ? 292  PHE A CD1 1 
ATOM   2137 C CD2 . PHE A 1 274  ? 140.347 147.281 148.130 1.00 244.19 ? 292  PHE A CD2 1 
ATOM   2138 C CE1 . PHE A 1 274  ? 142.929 146.494 148.684 1.00 248.86 ? 292  PHE A CE1 1 
ATOM   2139 C CE2 . PHE A 1 274  ? 141.288 148.219 148.508 1.00 245.57 ? 292  PHE A CE2 1 
ATOM   2140 C CZ  . PHE A 1 274  ? 142.579 147.824 148.789 1.00 247.96 ? 292  PHE A CZ  1 
ATOM   2141 N N   . SER A 1 275  ? 138.127 146.145 145.113 1.00 244.86 ? 293  SER A N   1 
ATOM   2142 C CA  . SER A 1 275  ? 137.690 147.315 144.369 1.00 245.38 ? 293  SER A CA  1 
ATOM   2143 C C   . SER A 1 275  ? 136.557 147.988 145.126 1.00 248.08 ? 293  SER A C   1 
ATOM   2144 O O   . SER A 1 275  ? 135.728 147.321 145.752 1.00 250.11 ? 293  SER A O   1 
ATOM   2145 C CB  . SER A 1 275  ? 137.227 146.946 142.952 1.00 241.67 ? 293  SER A CB  1 
ATOM   2146 O OG  . SER A 1 275  ? 135.935 146.365 142.973 1.00 241.97 ? 293  SER A OG  1 
ATOM   2147 N N   . PHE A 1 276  ? 136.534 149.318 145.062 1.00 247.07 ? 294  PHE A N   1 
ATOM   2148 C CA  . PHE A 1 276  ? 135.497 150.133 145.682 1.00 246.63 ? 294  PHE A CA  1 
ATOM   2149 C C   . PHE A 1 276  ? 134.709 150.856 144.602 1.00 245.56 ? 294  PHE A C   1 
ATOM   2150 O O   . PHE A 1 276  ? 135.286 151.338 143.619 1.00 242.01 ? 294  PHE A O   1 
ATOM   2151 C CB  . PHE A 1 276  ? 136.086 151.165 146.649 1.00 244.68 ? 294  PHE A CB  1 
ATOM   2152 C CG  . PHE A 1 276  ? 136.802 150.574 147.829 1.00 245.23 ? 294  PHE A CG  1 
ATOM   2153 C CD1 . PHE A 1 276  ? 136.180 149.656 148.659 1.00 246.72 ? 294  PHE A CD1 1 
ATOM   2154 C CD2 . PHE A 1 276  ? 138.099 150.958 148.120 1.00 242.72 ? 294  PHE A CD2 1 
ATOM   2155 C CE1 . PHE A 1 276  ? 136.843 149.126 149.746 1.00 244.90 ? 294  PHE A CE1 1 
ATOM   2156 C CE2 . PHE A 1 276  ? 138.765 150.432 149.205 1.00 243.21 ? 294  PHE A CE2 1 
ATOM   2157 C CZ  . PHE A 1 276  ? 138.137 149.515 150.019 1.00 244.62 ? 294  PHE A CZ  1 
ATOM   2158 N N   . ASN A 1 277  ? 133.393 150.926 144.795 1.00 248.39 ? 295  ASN A N   1 
ATOM   2159 C CA  . ASN A 1 277  ? 132.499 151.684 143.934 1.00 249.06 ? 295  ASN A CA  1 
ATOM   2160 C C   . ASN A 1 277  ? 132.329 153.096 144.495 1.00 252.22 ? 295  ASN A C   1 
ATOM   2161 O O   . ASN A 1 277  ? 132.919 153.464 145.512 1.00 251.68 ? 295  ASN A O   1 
ATOM   2162 C CB  . ASN A 1 277  ? 131.151 150.973 143.794 1.00 248.39 ? 295  ASN A CB  1 
ATOM   2163 C CG  . ASN A 1 277  ? 130.452 150.772 145.125 1.00 251.11 ? 295  ASN A CG  1 
ATOM   2164 O OD1 . ASN A 1 277  ? 129.863 151.700 145.675 1.00 252.51 ? 295  ASN A OD1 1 
ATOM   2165 N ND2 . ASN A 1 277  ? 130.515 149.553 145.650 1.00 251.35 ? 295  ASN A ND2 1 
ATOM   2166 N N   . ASP A 1 278  ? 131.503 153.901 143.822 1.00 254.86 ? 296  ASP A N   1 
ATOM   2167 C CA  . ASP A 1 278  ? 131.363 155.308 144.184 1.00 257.11 ? 296  ASP A CA  1 
ATOM   2168 C C   . ASP A 1 278  ? 130.480 155.531 145.406 1.00 255.57 ? 296  ASP A C   1 
ATOM   2169 O O   . ASP A 1 278  ? 130.571 156.595 146.028 1.00 255.30 ? 296  ASP A O   1 
ATOM   2170 C CB  . ASP A 1 278  ? 130.793 156.089 143.000 1.00 260.85 ? 296  ASP A CB  1 
ATOM   2171 C CG  . ASP A 1 278  ? 131.793 156.253 141.878 1.00 263.28 ? 296  ASP A CG  1 
ATOM   2172 O OD1 . ASP A 1 278  ? 132.469 155.261 141.540 1.00 263.48 ? 296  ASP A OD1 1 
ATOM   2173 O OD2 . ASP A 1 278  ? 131.895 157.369 141.328 1.00 264.74 ? 296  ASP A OD2 1 
ATOM   2174 N N   . GLU A 1 279  ? 129.637 154.568 145.771 1.00 254.47 ? 297  GLU A N   1 
ATOM   2175 C CA  . GLU A 1 279  ? 128.654 154.765 146.828 1.00 251.42 ? 297  GLU A CA  1 
ATOM   2176 C C   . GLU A 1 279  ? 129.233 154.584 148.229 1.00 250.12 ? 297  GLU A C   1 
ATOM   2177 O O   . GLU A 1 279  ? 128.513 154.797 149.211 1.00 246.07 ? 297  GLU A O   1 
ATOM   2178 C CB  . GLU A 1 279  ? 127.474 153.806 146.637 1.00 250.11 ? 297  GLU A CB  1 
ATOM   2179 C CG  . GLU A 1 279  ? 126.418 154.299 145.660 1.00 251.31 ? 297  GLU A CG  1 
ATOM   2180 C CD  . GLU A 1 279  ? 126.916 154.326 144.228 1.00 255.37 ? 297  GLU A CD  1 
ATOM   2181 O OE1 . GLU A 1 279  ? 127.356 153.268 143.732 1.00 253.86 ? 297  GLU A OE1 1 
ATOM   2182 O OE2 . GLU A 1 279  ? 126.869 155.404 143.601 1.00 257.79 ? 297  GLU A OE2 1 
ATOM   2183 N N   . GLU A 1 280  ? 130.507 154.210 148.350 1.00 252.88 ? 298  GLU A N   1 
ATOM   2184 C CA  . GLU A 1 280  ? 131.116 153.922 149.643 1.00 255.70 ? 298  GLU A CA  1 
ATOM   2185 C C   . GLU A 1 280  ? 131.727 155.148 150.307 1.00 258.88 ? 298  GLU A C   1 
ATOM   2186 O O   . GLU A 1 280  ? 131.598 155.307 151.525 1.00 258.23 ? 298  GLU A O   1 
ATOM   2187 C CB  . GLU A 1 280  ? 132.189 152.841 149.485 1.00 256.45 ? 298  GLU A CB  1 
ATOM   2188 C CG  . GLU A 1 280  ? 131.649 151.515 148.972 1.00 254.67 ? 298  GLU A CG  1 
ATOM   2189 C CD  . GLU A 1 280  ? 132.728 150.465 148.824 1.00 254.29 ? 298  GLU A CD  1 
ATOM   2190 O OE1 . GLU A 1 280  ? 133.377 150.132 149.838 1.00 254.05 ? 298  GLU A OE1 1 
ATOM   2191 O OE2 . GLU A 1 280  ? 132.921 149.967 147.696 1.00 253.75 ? 298  GLU A OE2 1 
ATOM   2192 N N   . MET A 1 281  ? 132.374 156.024 149.536 1.00 260.74 ? 299  MET A N   1 
ATOM   2193 C CA  . MET A 1 281  ? 133.018 157.219 150.073 1.00 265.26 ? 299  MET A CA  1 
ATOM   2194 C C   . MET A 1 281  ? 132.150 158.467 149.932 1.00 268.12 ? 299  MET A C   1 
ATOM   2195 O O   . MET A 1 281  ? 132.654 159.580 150.108 1.00 274.35 ? 299  MET A O   1 
ATOM   2196 C CB  . MET A 1 281  ? 134.379 157.460 149.402 1.00 265.88 ? 299  MET A CB  1 
ATOM   2197 C CG  . MET A 1 281  ? 134.387 157.434 147.880 1.00 262.32 ? 299  MET A CG  1 
ATOM   2198 S SD  . MET A 1 281  ? 133.924 155.843 147.183 1.00 256.10 ? 299  MET A SD  1 
ATOM   2199 C CE  . MET A 1 281  ? 135.418 154.904 147.489 1.00 248.31 ? 299  MET A CE  1 
ATOM   2200 N N   . LYS A 1 282  ? 130.865 158.310 149.598 1.00 262.59 ? 300  LYS A N   1 
ATOM   2201 C CA  . LYS A 1 282  ? 129.934 159.432 149.694 1.00 263.35 ? 300  LYS A CA  1 
ATOM   2202 C C   . LYS A 1 282  ? 129.943 160.032 151.093 1.00 272.29 ? 300  LYS A C   1 
ATOM   2203 O O   . LYS A 1 282  ? 130.037 161.259 151.250 1.00 279.86 ? 300  LYS A O   1 
ATOM   2204 C CB  . LYS A 1 282  ? 128.511 158.993 149.317 1.00 254.48 ? 300  LYS A CB  1 
ATOM   2205 C CG  . LYS A 1 282  ? 127.975 157.688 149.958 1.00 249.32 ? 300  LYS A CG  1 
ATOM   2206 C CD  . LYS A 1 282  ? 126.981 157.966 151.082 1.00 246.06 ? 300  LYS A CD  1 
ATOM   2207 C CE  . LYS A 1 282  ? 126.829 156.764 152.007 1.00 240.42 ? 300  LYS A CE  1 
ATOM   2208 N NZ  . LYS A 1 282  ? 125.970 157.062 153.187 1.00 233.65 ? 300  LYS A NZ  1 
ATOM   2209 N N   . ASN A 1 283  ? 129.933 159.175 152.118 1.00 269.54 ? 301  ASN A N   1 
ATOM   2210 C CA  . ASN A 1 283  ? 129.930 159.626 153.504 1.00 274.02 ? 301  ASN A CA  1 
ATOM   2211 C C   . ASN A 1 283  ? 131.143 160.481 153.851 1.00 280.69 ? 301  ASN A C   1 
ATOM   2212 O O   . ASN A 1 283  ? 131.085 161.246 154.820 1.00 284.34 ? 301  ASN A O   1 
ATOM   2213 C CB  . ASN A 1 283  ? 129.875 158.414 154.431 1.00 266.70 ? 301  ASN A CB  1 
ATOM   2214 C CG  . ASN A 1 283  ? 131.186 157.653 154.467 1.00 264.78 ? 301  ASN A CG  1 
ATOM   2215 O OD1 . ASN A 1 283  ? 131.768 157.349 153.426 1.00 262.54 ? 301  ASN A OD1 1 
ATOM   2216 N ND2 . ASN A 1 283  ? 131.657 157.340 155.668 1.00 264.04 ? 301  ASN A ND2 1 
ATOM   2217 N N   . VAL A 1 284  ? 132.236 160.370 153.088 1.00 279.78 ? 302  VAL A N   1 
ATOM   2218 C CA  . VAL A 1 284  ? 133.411 161.197 153.343 1.00 281.60 ? 302  VAL A CA  1 
ATOM   2219 C C   . VAL A 1 284  ? 133.065 162.673 153.204 1.00 288.04 ? 302  VAL A C   1 
ATOM   2220 O O   . VAL A 1 284  ? 133.529 163.504 153.996 1.00 286.69 ? 302  VAL A O   1 
ATOM   2221 C CB  . VAL A 1 284  ? 134.569 160.798 152.408 1.00 277.95 ? 302  VAL A CB  1 
ATOM   2222 C CG1 . VAL A 1 284  ? 135.764 161.728 152.624 1.00 277.93 ? 302  VAL A CG1 1 
ATOM   2223 C CG2 . VAL A 1 284  ? 134.955 159.338 152.630 1.00 274.86 ? 302  VAL A CG2 1 
ATOM   2224 N N   . MET A 1 285  ? 132.245 163.027 152.207 1.00 292.40 ? 303  MET A N   1 
ATOM   2225 C CA  . MET A 1 285  ? 131.726 164.386 152.085 1.00 296.11 ? 303  MET A CA  1 
ATOM   2226 C C   . MET A 1 285  ? 130.343 164.545 152.707 1.00 299.44 ? 303  MET A C   1 
ATOM   2227 O O   . MET A 1 285  ? 129.674 165.549 152.444 1.00 303.15 ? 303  MET A O   1 
ATOM   2228 C CB  . MET A 1 285  ? 131.704 164.845 150.622 1.00 296.28 ? 303  MET A CB  1 
ATOM   2229 C CG  . MET A 1 285  ? 132.896 164.398 149.788 1.00 290.43 ? 303  MET A CG  1 
ATOM   2230 S SD  . MET A 1 285  ? 133.013 162.625 149.527 1.00 287.29 ? 303  MET A SD  1 
ATOM   2231 C CE  . MET A 1 285  ? 131.654 162.395 148.385 1.00 275.67 ? 303  MET A CE  1 
ATOM   2232 N N   . ASP A 1 286  ? 129.898 163.572 153.514 1.00 299.15 ? 304  ASP A N   1 
ATOM   2233 C CA  . ASP A 1 286  ? 128.746 163.739 154.390 1.00 301.34 ? 304  ASP A CA  1 
ATOM   2234 C C   . ASP A 1 286  ? 129.129 163.885 155.855 1.00 299.48 ? 304  ASP A C   1 
ATOM   2235 O O   . ASP A 1 286  ? 128.348 164.453 156.625 1.00 302.30 ? 304  ASP A O   1 
ATOM   2236 C CB  . ASP A 1 286  ? 127.788 162.548 154.248 1.00 299.62 ? 304  ASP A CB  1 
ATOM   2237 C CG  . ASP A 1 286  ? 126.339 162.940 154.457 1.00 304.00 ? 304  ASP A CG  1 
ATOM   2238 O OD1 . ASP A 1 286  ? 125.832 163.784 153.688 1.00 307.55 ? 304  ASP A OD1 1 
ATOM   2239 O OD2 . ASP A 1 286  ? 125.707 162.407 155.393 1.00 303.35 ? 304  ASP A OD2 1 
ATOM   2240 N N   . SER A 1 287  ? 130.302 163.389 156.256 1.00 296.11 ? 305  SER A N   1 
ATOM   2241 C CA  . SER A 1 287  ? 130.747 163.560 157.635 1.00 293.12 ? 305  SER A CA  1 
ATOM   2242 C C   . SER A 1 287  ? 130.993 165.028 157.957 1.00 293.39 ? 305  SER A C   1 
ATOM   2243 O O   . SER A 1 287  ? 130.613 165.505 159.033 1.00 291.64 ? 305  SER A O   1 
ATOM   2244 C CB  . SER A 1 287  ? 132.014 162.740 157.877 1.00 287.81 ? 305  SER A CB  1 
ATOM   2245 O OG  . SER A 1 287  ? 132.239 162.543 159.262 1.00 288.11 ? 305  SER A OG  1 
ATOM   2246 N N   . SER A 1 288  ? 131.621 165.758 157.037 1.00 292.54 ? 306  SER A N   1 
ATOM   2247 C CA  . SER A 1 288  ? 131.918 167.175 157.226 1.00 287.12 ? 306  SER A CA  1 
ATOM   2248 C C   . SER A 1 288  ? 130.827 168.043 156.607 1.00 281.99 ? 306  SER A C   1 
ATOM   2249 O O   . SER A 1 288  ? 130.311 168.958 157.248 1.00 271.18 ? 306  SER A O   1 
ATOM   2250 C CB  . SER A 1 288  ? 133.276 167.522 156.612 1.00 283.01 ? 306  SER A CB  1 
ATOM   2251 O OG  . SER A 1 288  ? 133.229 167.459 155.197 1.00 280.17 ? 306  SER A OG  1 
ATOM   2252 N N   . SER A 1 298  ? 133.960 171.868 151.598 1.00 255.88 ? 316  SER A N   1 
ATOM   2253 C CA  . SER A 1 298  ? 133.950 170.431 151.843 1.00 261.78 ? 316  SER A CA  1 
ATOM   2254 C C   . SER A 1 298  ? 134.883 169.709 150.878 1.00 268.95 ? 316  SER A C   1 
ATOM   2255 O O   . SER A 1 298  ? 134.530 168.668 150.323 1.00 272.65 ? 316  SER A O   1 
ATOM   2256 C CB  . SER A 1 298  ? 132.529 169.876 151.717 1.00 257.60 ? 316  SER A CB  1 
ATOM   2257 O OG  . SER A 1 298  ? 132.074 169.927 150.375 1.00 252.71 ? 316  SER A OG  1 
ATOM   2258 N N   . SER A 1 299  ? 136.073 170.268 150.677 1.00 270.90 ? 317  SER A N   1 
ATOM   2259 C CA  . SER A 1 299  ? 137.033 169.649 149.777 1.00 271.55 ? 317  SER A CA  1 
ATOM   2260 C C   . SER A 1 299  ? 137.520 168.325 150.371 1.00 272.81 ? 317  SER A C   1 
ATOM   2261 O O   . SER A 1 299  ? 137.727 168.235 151.586 1.00 272.21 ? 317  SER A O   1 
ATOM   2262 C CB  . SER A 1 299  ? 138.219 170.581 149.537 1.00 268.96 ? 317  SER A CB  1 
ATOM   2263 O OG  . SER A 1 299  ? 139.186 169.971 148.700 1.00 267.11 ? 317  SER A OG  1 
ATOM   2264 N N   . PRO A 1 300  ? 137.715 167.281 149.557 1.00 272.95 ? 318  PRO A N   1 
ATOM   2265 C CA  . PRO A 1 300  ? 138.122 165.993 150.129 1.00 272.10 ? 318  PRO A CA  1 
ATOM   2266 C C   . PRO A 1 300  ? 139.617 165.940 150.402 1.00 270.49 ? 318  PRO A C   1 
ATOM   2267 O O   . PRO A 1 300  ? 140.438 166.313 149.560 1.00 270.01 ? 318  PRO A O   1 
ATOM   2268 C CB  . PRO A 1 300  ? 137.722 164.986 149.045 1.00 269.38 ? 318  PRO A CB  1 
ATOM   2269 C CG  . PRO A 1 300  ? 137.876 165.740 147.783 1.00 264.48 ? 318  PRO A CG  1 
ATOM   2270 C CD  . PRO A 1 300  ? 137.573 167.187 148.090 1.00 268.95 ? 318  PRO A CD  1 
ATOM   2271 N N   . GLY A 1 301  ? 139.959 165.461 151.597 1.00 269.07 ? 319  GLY A N   1 
ATOM   2272 C CA  . GLY A 1 301  ? 141.334 165.302 152.010 1.00 268.56 ? 319  GLY A CA  1 
ATOM   2273 C C   . GLY A 1 301  ? 141.775 163.854 151.921 1.00 270.45 ? 319  GLY A C   1 
ATOM   2274 O O   . GLY A 1 301  ? 141.087 163.013 151.333 1.00 269.81 ? 319  GLY A O   1 
ATOM   2275 N N   . PRO A 1 302  ? 142.931 163.529 152.497 1.00 271.89 ? 320  PRO A N   1 
ATOM   2276 C CA  . PRO A 1 302  ? 143.388 162.136 152.479 1.00 273.09 ? 320  PRO A CA  1 
ATOM   2277 C C   . PRO A 1 302  ? 142.517 161.244 153.349 1.00 277.55 ? 320  PRO A C   1 
ATOM   2278 O O   . PRO A 1 302  ? 141.783 161.702 154.227 1.00 278.77 ? 320  PRO A O   1 
ATOM   2279 C CB  . PRO A 1 302  ? 144.821 162.216 153.018 1.00 268.18 ? 320  PRO A CB  1 
ATOM   2280 C CG  . PRO A 1 302  ? 144.875 163.484 153.786 1.00 265.79 ? 320  PRO A CG  1 
ATOM   2281 C CD  . PRO A 1 302  ? 143.925 164.426 153.114 1.00 266.60 ? 320  PRO A CD  1 
ATOM   2282 N N   . VAL A 1 303  ? 142.597 159.941 153.069 1.00 278.26 ? 321  VAL A N   1 
ATOM   2283 C CA  . VAL A 1 303  ? 141.830 158.921 153.771 1.00 278.93 ? 321  VAL A CA  1 
ATOM   2284 C C   . VAL A 1 303  ? 142.774 157.792 154.158 1.00 277.08 ? 321  VAL A C   1 
ATOM   2285 O O   . VAL A 1 303  ? 143.706 157.451 153.425 1.00 275.42 ? 321  VAL A O   1 
ATOM   2286 C CB  . VAL A 1 303  ? 140.655 158.380 152.921 1.00 277.09 ? 321  VAL A CB  1 
ATOM   2287 C CG1 . VAL A 1 303  ? 139.619 159.473 152.685 1.00 276.82 ? 321  VAL A CG1 1 
ATOM   2288 C CG2 . VAL A 1 303  ? 141.144 157.806 151.584 1.00 274.83 ? 321  VAL A CG2 1 
ATOM   2289 N N   . GLU A 1 304  ? 142.512 157.203 155.324 1.00 276.70 ? 322  GLU A N   1 
ATOM   2290 C CA  . GLU A 1 304  ? 143.343 156.146 155.885 1.00 274.96 ? 322  GLU A CA  1 
ATOM   2291 C C   . GLU A 1 304  ? 142.697 154.795 155.611 1.00 275.52 ? 322  GLU A C   1 
ATOM   2292 O O   . GLU A 1 304  ? 141.530 154.576 155.958 1.00 275.60 ? 322  GLU A O   1 
ATOM   2293 C CB  . GLU A 1 304  ? 143.539 156.347 157.390 1.00 273.91 ? 322  GLU A CB  1 
ATOM   2294 C CG  . GLU A 1 304  ? 144.345 155.240 158.074 1.00 273.46 ? 322  GLU A CG  1 
ATOM   2295 C CD  . GLU A 1 304  ? 144.767 155.596 159.490 1.00 275.48 ? 322  GLU A CD  1 
ATOM   2296 O OE1 . GLU A 1 304  ? 144.930 156.797 159.791 1.00 277.40 ? 322  GLU A OE1 1 
ATOM   2297 O OE2 . GLU A 1 304  ? 144.935 154.666 160.306 1.00 275.02 ? 322  GLU A OE2 1 
ATOM   2298 N N   . ILE A 1 305  ? 143.462 153.897 154.996 1.00 274.73 ? 323  ILE A N   1 
ATOM   2299 C CA  . ILE A 1 305  ? 143.042 152.525 154.737 1.00 273.23 ? 323  ILE A CA  1 
ATOM   2300 C C   . ILE A 1 305  ? 143.957 151.619 155.547 1.00 269.78 ? 323  ILE A C   1 
ATOM   2301 O O   . ILE A 1 305  ? 145.182 151.646 155.369 1.00 269.52 ? 323  ILE A O   1 
ATOM   2302 C CB  . ILE A 1 305  ? 143.100 152.184 153.239 1.00 272.83 ? 323  ILE A CB  1 
ATOM   2303 C CG1 . ILE A 1 305  ? 142.163 153.119 152.462 1.00 272.85 ? 323  ILE A CG1 1 
ATOM   2304 C CG2 . ILE A 1 305  ? 142.742 150.705 152.999 1.00 269.16 ? 323  ILE A CG2 1 
ATOM   2305 C CD1 . ILE A 1 305  ? 142.888 154.231 151.737 1.00 274.11 ? 323  ILE A CD1 1 
ATOM   2306 N N   . LEU A 1 306  ? 143.363 150.825 156.436 1.00 266.84 ? 324  LEU A N   1 
ATOM   2307 C CA  . LEU A 1 306  ? 144.084 149.903 157.302 1.00 264.21 ? 324  LEU A CA  1 
ATOM   2308 C C   . LEU A 1 306  ? 143.656 148.487 156.953 1.00 264.97 ? 324  LEU A C   1 
ATOM   2309 O O   . LEU A 1 306  ? 142.461 148.217 156.810 1.00 263.65 ? 324  LEU A O   1 
ATOM   2310 C CB  . LEU A 1 306  ? 143.802 150.206 158.779 1.00 261.59 ? 324  LEU A CB  1 
ATOM   2311 C CG  . LEU A 1 306  ? 144.428 149.321 159.867 1.00 259.07 ? 324  LEU A CG  1 
ATOM   2312 C CD1 . LEU A 1 306  ? 145.824 149.806 160.218 1.00 257.57 ? 324  LEU A CD1 1 
ATOM   2313 C CD2 . LEU A 1 306  ? 143.545 149.297 161.103 1.00 257.27 ? 324  LEU A CD2 1 
ATOM   2314 N N   . THR A 1 307  ? 144.630 147.593 156.809 1.00 266.59 ? 325  THR A N   1 
ATOM   2315 C CA  . THR A 1 307  ? 144.385 146.177 156.572 1.00 267.78 ? 325  THR A CA  1 
ATOM   2316 C C   . THR A 1 307  ? 144.930 145.382 157.748 1.00 266.03 ? 325  THR A C   1 
ATOM   2317 O O   . THR A 1 307  ? 146.098 145.538 158.124 1.00 263.84 ? 325  THR A O   1 
ATOM   2318 C CB  . THR A 1 307  ? 145.015 145.701 155.254 1.00 269.94 ? 325  THR A CB  1 
ATOM   2319 O OG1 . THR A 1 307  ? 144.842 144.284 155.128 1.00 270.45 ? 325  THR A OG1 1 
ATOM   2320 C CG2 . THR A 1 307  ? 146.512 146.040 155.156 1.00 265.32 ? 325  THR A CG2 1 
ATOM   2321 N N   . THR A 1 308  ? 144.069 144.554 158.338 1.00 266.38 ? 326  THR A N   1 
ATOM   2322 C CA  . THR A 1 308  ? 144.420 143.659 159.436 1.00 264.75 ? 326  THR A CA  1 
ATOM   2323 C C   . THR A 1 308  ? 144.314 142.237 158.906 1.00 265.06 ? 326  THR A C   1 
ATOM   2324 O O   . THR A 1 308  ? 143.210 141.758 158.624 1.00 264.41 ? 326  THR A O   1 
ATOM   2325 C CB  . THR A 1 308  ? 143.500 143.873 160.638 1.00 262.06 ? 326  THR A CB  1 
ATOM   2326 O OG1 . THR A 1 308  ? 143.525 145.254 161.021 1.00 259.71 ? 326  THR A OG1 1 
ATOM   2327 C CG2 . THR A 1 308  ? 143.942 143.016 161.818 1.00 259.34 ? 326  THR A CG2 1 
ATOM   2328 N N   . VAL A 1 309  ? 145.460 141.578 158.757 1.00 264.97 ? 327  VAL A N   1 
ATOM   2329 C CA  . VAL A 1 309  ? 145.551 140.230 158.204 1.00 265.27 ? 327  VAL A CA  1 
ATOM   2330 C C   . VAL A 1 309  ? 145.834 139.275 159.353 1.00 264.69 ? 327  VAL A C   1 
ATOM   2331 O O   . VAL A 1 309  ? 146.837 139.428 160.062 1.00 263.04 ? 327  VAL A O   1 
ATOM   2332 C CB  . VAL A 1 309  ? 146.641 140.135 157.126 1.00 264.75 ? 327  VAL A CB  1 
ATOM   2333 C CG1 . VAL A 1 309  ? 146.556 138.796 156.392 1.00 265.36 ? 327  VAL A CG1 1 
ATOM   2334 C CG2 . VAL A 1 309  ? 146.525 141.303 156.150 1.00 265.61 ? 327  VAL A CG2 1 
ATOM   2335 N N   . THR A 1 310  ? 144.947 138.297 159.535 1.00 265.93 ? 328  THR A N   1 
ATOM   2336 C CA  . THR A 1 310  ? 145.060 137.284 160.575 1.00 266.79 ? 328  THR A CA  1 
ATOM   2337 C C   . THR A 1 310  ? 145.085 135.911 159.922 1.00 268.62 ? 328  THR A C   1 
ATOM   2338 O O   . THR A 1 310  ? 144.196 135.579 159.130 1.00 267.52 ? 328  THR A O   1 
ATOM   2339 C CB  . THR A 1 310  ? 143.894 137.379 161.564 1.00 265.18 ? 328  THR A CB  1 
ATOM   2340 O OG1 . THR A 1 310  ? 143.754 138.733 162.013 1.00 262.54 ? 328  THR A OG1 1 
ATOM   2341 C CG2 . THR A 1 310  ? 144.124 136.469 162.764 1.00 265.33 ? 328  THR A CG2 1 
ATOM   2342 N N   . GLU A 1 311  ? 146.098 135.118 160.254 1.00 270.28 ? 329  GLU A N   1 
ATOM   2343 C CA  . GLU A 1 311  ? 146.174 133.761 159.735 1.00 272.16 ? 329  GLU A CA  1 
ATOM   2344 C C   . GLU A 1 311  ? 145.152 132.876 160.434 1.00 275.08 ? 329  GLU A C   1 
ATOM   2345 O O   . GLU A 1 311  ? 144.916 133.001 161.639 1.00 274.25 ? 329  GLU A O   1 
ATOM   2346 C CB  . GLU A 1 311  ? 147.578 133.194 159.927 1.00 271.32 ? 329  GLU A CB  1 
ATOM   2347 C CG  . GLU A 1 311  ? 147.898 132.019 159.020 1.00 270.34 ? 329  GLU A CG  1 
ATOM   2348 C CD  . GLU A 1 311  ? 149.318 131.520 159.193 1.00 269.11 ? 329  GLU A CD  1 
ATOM   2349 O OE1 . GLU A 1 311  ? 150.006 131.993 160.122 1.00 268.81 ? 329  GLU A OE1 1 
ATOM   2350 O OE2 . GLU A 1 311  ? 149.747 130.656 158.400 1.00 267.27 ? 329  GLU A OE2 1 
ATOM   2351 N N   . SER A 1 312  ? 144.542 131.972 159.667 1.00 276.36 ? 330  SER A N   1 
ATOM   2352 C CA  . SER A 1 312  ? 143.525 131.094 160.234 1.00 278.47 ? 330  SER A CA  1 
ATOM   2353 C C   . SER A 1 312  ? 144.125 130.078 161.197 1.00 280.11 ? 330  SER A C   1 
ATOM   2354 O O   . SER A 1 312  ? 143.483 129.718 162.190 1.00 279.90 ? 330  SER A O   1 
ATOM   2355 C CB  . SER A 1 312  ? 142.773 130.376 159.114 1.00 276.61 ? 330  SER A CB  1 
ATOM   2356 O OG  . SER A 1 312  ? 143.663 129.632 158.300 1.00 273.56 ? 330  SER A OG  1 
ATOM   2357 N N   . VAL A 1 313  ? 145.349 129.619 160.934 1.00 281.11 ? 331  VAL A N   1 
ATOM   2358 C CA  . VAL A 1 313  ? 145.921 128.521 161.713 1.00 280.84 ? 331  VAL A CA  1 
ATOM   2359 C C   . VAL A 1 313  ? 146.681 129.016 162.944 1.00 280.66 ? 331  VAL A C   1 
ATOM   2360 O O   . VAL A 1 313  ? 146.649 128.354 163.987 1.00 281.69 ? 331  VAL A O   1 
ATOM   2361 C CB  . VAL A 1 313  ? 146.821 127.620 160.840 1.00 278.55 ? 331  VAL A CB  1 
ATOM   2362 C CG1 . VAL A 1 313  ? 145.967 126.770 159.909 1.00 276.15 ? 331  VAL A CG1 1 
ATOM   2363 C CG2 . VAL A 1 313  ? 147.861 128.415 160.038 1.00 277.23 ? 331  VAL A CG2 1 
ATOM   2364 N N   . THR A 1 314  ? 147.355 130.167 162.855 1.00 279.03 ? 332  THR A N   1 
ATOM   2365 C CA  . THR A 1 314  ? 148.104 130.734 163.973 1.00 276.42 ? 332  THR A CA  1 
ATOM   2366 C C   . THR A 1 314  ? 147.397 131.892 164.655 1.00 274.28 ? 332  THR A C   1 
ATOM   2367 O O   . THR A 1 314  ? 147.634 132.127 165.842 1.00 272.54 ? 332  THR A O   1 
ATOM   2368 C CB  . THR A 1 314  ? 149.486 131.219 163.510 1.00 270.58 ? 332  THR A CB  1 
ATOM   2369 O OG1 . THR A 1 314  ? 149.340 132.341 162.631 1.00 267.49 ? 332  THR A OG1 1 
ATOM   2370 C CG2 . THR A 1 314  ? 150.244 130.104 162.800 1.00 269.30 ? 332  THR A CG2 1 
ATOM   2371 N N   . GLY A 1 315  ? 146.540 132.620 163.944 1.00 273.12 ? 333  GLY A N   1 
ATOM   2372 C CA  . GLY A 1 315  ? 145.849 133.748 164.532 1.00 268.40 ? 333  GLY A CA  1 
ATOM   2373 C C   . GLY A 1 315  ? 146.698 134.981 164.734 1.00 265.12 ? 333  GLY A C   1 
ATOM   2374 O O   . GLY A 1 315  ? 146.285 135.880 165.476 1.00 263.35 ? 333  GLY A O   1 
ATOM   2375 N N   . ILE A 1 316  ? 147.865 135.059 164.101 1.00 263.53 ? 334  ILE A N   1 
ATOM   2376 C CA  . ILE A 1 316  ? 148.753 136.204 164.267 1.00 258.46 ? 334  ILE A CA  1 
ATOM   2377 C C   . ILE A 1 316  ? 148.222 137.348 163.413 1.00 257.85 ? 334  ILE A C   1 
ATOM   2378 O O   . ILE A 1 316  ? 148.143 137.234 162.186 1.00 257.12 ? 334  ILE A O   1 
ATOM   2379 C CB  . ILE A 1 316  ? 150.197 135.847 163.885 1.00 253.02 ? 334  ILE A CB  1 
ATOM   2380 C CG1 . ILE A 1 316  ? 150.795 134.870 164.903 1.00 252.90 ? 334  ILE A CG1 1 
ATOM   2381 C CG2 . ILE A 1 316  ? 151.063 137.103 163.806 1.00 247.87 ? 334  ILE A CG2 1 
ATOM   2382 C CD1 . ILE A 1 316  ? 151.920 134.026 164.351 1.00 246.84 ? 334  ILE A CD1 1 
ATOM   2383 N N   . SER A 1 317  ? 147.872 138.455 164.063 1.00 258.90 ? 335  SER A N   1 
ATOM   2384 C CA  . SER A 1 317  ? 147.275 139.608 163.402 1.00 260.47 ? 335  SER A CA  1 
ATOM   2385 C C   . SER A 1 317  ? 148.348 140.649 163.116 1.00 258.03 ? 335  SER A C   1 
ATOM   2386 O O   . SER A 1 317  ? 149.063 141.076 164.029 1.00 255.36 ? 335  SER A O   1 
ATOM   2387 C CB  . SER A 1 317  ? 146.171 140.216 164.268 1.00 260.34 ? 335  SER A CB  1 
ATOM   2388 O OG  . SER A 1 317  ? 146.691 141.218 165.124 1.00 258.99 ? 335  SER A OG  1 
ATOM   2389 N N   . ARG A 1 318  ? 148.456 141.046 161.849 1.00 257.68 ? 336  ARG A N   1 
ATOM   2390 C CA  . ARG A 1 318  ? 149.365 142.096 161.407 1.00 253.27 ? 336  ARG A CA  1 
ATOM   2391 C C   . ARG A 1 318  ? 148.549 143.229 160.803 1.00 252.87 ? 336  ARG A C   1 
ATOM   2392 O O   . ARG A 1 318  ? 147.691 142.989 159.948 1.00 255.84 ? 336  ARG A O   1 
ATOM   2393 C CB  . ARG A 1 318  ? 150.371 141.565 160.382 1.00 250.97 ? 336  ARG A CB  1 
ATOM   2394 C CG  . ARG A 1 318  ? 151.575 140.861 160.999 1.00 249.34 ? 336  ARG A CG  1 
ATOM   2395 C CD  . ARG A 1 318  ? 152.624 141.847 161.502 1.00 245.31 ? 336  ARG A CD  1 
ATOM   2396 N NE  . ARG A 1 318  ? 153.245 142.602 160.417 1.00 242.50 ? 336  ARG A NE  1 
ATOM   2397 C CZ  . ARG A 1 318  ? 153.862 143.771 160.549 1.00 237.56 ? 336  ARG A CZ  1 
ATOM   2398 N NH1 . ARG A 1 318  ? 153.990 144.368 161.726 1.00 234.71 ? 336  ARG A NH1 1 
ATOM   2399 N NH2 . ARG A 1 318  ? 154.370 144.359 159.470 1.00 235.03 ? 336  ARG A NH2 1 
ATOM   2400 N N   . ASN A 1 319  ? 148.834 144.455 161.237 1.00 249.83 ? 337  ASN A N   1 
ATOM   2401 C CA  . ASN A 1 319  ? 148.089 145.643 160.835 1.00 251.34 ? 337  ASN A CA  1 
ATOM   2402 C C   . ASN A 1 319  ? 149.004 146.565 160.042 1.00 251.19 ? 337  ASN A C   1 
ATOM   2403 O O   . ASN A 1 319  ? 150.103 146.895 160.500 1.00 246.14 ? 337  ASN A O   1 
ATOM   2404 C CB  . ASN A 1 319  ? 147.515 146.388 162.047 1.00 246.71 ? 337  ASN A CB  1 
ATOM   2405 C CG  . ASN A 1 319  ? 148.504 146.505 163.193 1.00 237.63 ? 337  ASN A CG  1 
ATOM   2406 O OD1 . ASN A 1 319  ? 149.586 145.921 163.155 1.00 239.07 ? 337  ASN A OD1 1 
ATOM   2407 N ND2 . ASN A 1 319  ? 148.136 147.265 164.218 1.00 224.60 ? 337  ASN A ND2 1 
ATOM   2408 N N   . VAL A 1 320  ? 148.550 146.969 158.856 1.00 255.35 ? 338  VAL A N   1 
ATOM   2409 C CA  . VAL A 1 320  ? 149.298 147.865 157.977 1.00 255.80 ? 338  VAL A CA  1 
ATOM   2410 C C   . VAL A 1 320  ? 148.359 148.979 157.537 1.00 259.64 ? 338  VAL A C   1 
ATOM   2411 O O   . VAL A 1 320  ? 147.270 148.705 157.019 1.00 261.75 ? 338  VAL A O   1 
ATOM   2412 C CB  . VAL A 1 320  ? 149.877 147.125 156.759 1.00 253.77 ? 338  VAL A CB  1 
ATOM   2413 C CG1 . VAL A 1 320  ? 150.400 148.112 155.712 1.00 251.83 ? 338  VAL A CG1 1 
ATOM   2414 C CG2 . VAL A 1 320  ? 150.977 146.167 157.198 1.00 250.80 ? 338  VAL A CG2 1 
ATOM   2415 N N   . SER A 1 321  ? 148.787 150.226 157.722 1.00 260.31 ? 339  SER A N   1 
ATOM   2416 C CA  . SER A 1 321  ? 147.997 151.405 157.394 1.00 263.09 ? 339  SER A CA  1 
ATOM   2417 C C   . SER A 1 321  ? 148.658 152.185 156.266 1.00 264.10 ? 339  SER A C   1 
ATOM   2418 O O   . SER A 1 321  ? 149.884 152.197 156.130 1.00 261.24 ? 339  SER A O   1 
ATOM   2419 C CB  . SER A 1 321  ? 147.833 152.313 158.617 1.00 262.79 ? 339  SER A CB  1 
ATOM   2420 O OG  . SER A 1 321  ? 148.974 153.134 158.797 1.00 260.95 ? 339  SER A OG  1 
ATOM   2421 N N   . THR A 1 322  ? 147.826 152.837 155.454 1.00 267.76 ? 340  THR A N   1 
ATOM   2422 C CA  . THR A 1 322  ? 148.297 153.680 154.366 1.00 268.93 ? 340  THR A CA  1 
ATOM   2423 C C   . THR A 1 322  ? 147.342 154.853 154.205 1.00 271.71 ? 340  THR A C   1 
ATOM   2424 O O   . THR A 1 322  ? 146.195 154.812 154.659 1.00 271.79 ? 340  THR A O   1 
ATOM   2425 C CB  . THR A 1 322  ? 148.414 152.899 153.046 1.00 265.63 ? 340  THR A CB  1 
ATOM   2426 O OG1 . THR A 1 322  ? 149.148 153.674 152.090 1.00 263.83 ? 340  THR A OG1 1 
ATOM   2427 C CG2 . THR A 1 322  ? 147.038 152.579 152.472 1.00 266.92 ? 340  THR A CG2 1 
ATOM   2428 N N   . ASN A 1 323  ? 147.834 155.903 153.549 1.00 272.26 ? 341  ASN A N   1 
ATOM   2429 C CA  . ASN A 1 323  ? 147.083 157.128 153.306 1.00 272.19 ? 341  ASN A CA  1 
ATOM   2430 C C   . ASN A 1 323  ? 146.959 157.347 151.806 1.00 271.49 ? 341  ASN A C   1 
ATOM   2431 O O   . ASN A 1 323  ? 147.943 157.201 151.073 1.00 268.12 ? 341  ASN A O   1 
ATOM   2432 C CB  . ASN A 1 323  ? 147.767 158.329 153.964 1.00 270.79 ? 341  ASN A CB  1 
ATOM   2433 C CG  . ASN A 1 323  ? 147.742 158.255 155.477 1.00 268.78 ? 341  ASN A CG  1 
ATOM   2434 O OD1 . ASN A 1 323  ? 146.876 157.608 156.065 1.00 269.58 ? 341  ASN A OD1 1 
ATOM   2435 N ND2 . ASN A 1 323  ? 148.698 158.919 156.117 1.00 265.93 ? 341  ASN A ND2 1 
ATOM   2436 N N   . VAL A 1 324  ? 145.753 157.693 151.359 1.00 272.36 ? 342  VAL A N   1 
ATOM   2437 C CA  . VAL A 1 324  ? 145.455 157.927 149.948 1.00 270.27 ? 342  VAL A CA  1 
ATOM   2438 C C   . VAL A 1 324  ? 144.831 159.309 149.828 1.00 269.30 ? 342  VAL A C   1 
ATOM   2439 O O   . VAL A 1 324  ? 143.802 159.587 150.455 1.00 270.74 ? 342  VAL A O   1 
ATOM   2440 C CB  . VAL A 1 324  ? 144.521 156.847 149.378 1.00 268.75 ? 342  VAL A CB  1 
ATOM   2441 C CG1 . VAL A 1 324  ? 143.971 157.258 148.011 1.00 265.59 ? 342  VAL A CG1 1 
ATOM   2442 C CG2 . VAL A 1 324  ? 145.250 155.517 149.286 1.00 267.42 ? 342  VAL A CG2 1 
ATOM   2443 N N   . PHE A 1 325  ? 145.449 160.171 149.026 1.00 266.52 ? 343  PHE A N   1 
ATOM   2444 C CA  . PHE A 1 325  ? 144.908 161.499 148.788 1.00 263.64 ? 343  PHE A CA  1 
ATOM   2445 C C   . PHE A 1 325  ? 143.746 161.436 147.806 1.00 261.00 ? 343  PHE A C   1 
ATOM   2446 O O   . PHE A 1 325  ? 143.713 160.597 146.901 1.00 259.79 ? 343  PHE A O   1 
ATOM   2447 C CB  . PHE A 1 325  ? 145.987 162.436 148.251 1.00 262.18 ? 343  PHE A CB  1 
ATOM   2448 C CG  . PHE A 1 325  ? 147.127 162.655 149.201 1.00 262.55 ? 343  PHE A CG  1 
ATOM   2449 C CD1 . PHE A 1 325  ? 147.062 163.650 150.162 1.00 261.03 ? 343  PHE A CD1 1 
ATOM   2450 C CD2 . PHE A 1 325  ? 148.264 161.868 149.133 1.00 261.09 ? 343  PHE A CD2 1 
ATOM   2451 C CE1 . PHE A 1 325  ? 148.110 163.855 151.038 1.00 258.12 ? 343  PHE A CE1 1 
ATOM   2452 C CE2 . PHE A 1 325  ? 149.315 162.069 150.007 1.00 257.52 ? 343  PHE A CE2 1 
ATOM   2453 C CZ  . PHE A 1 325  ? 149.238 163.063 150.960 1.00 255.71 ? 343  PHE A CZ  1 
ATOM   2454 N N   . PHE A 1 326  ? 142.788 162.341 147.998 1.00 260.14 ? 344  PHE A N   1 
ATOM   2455 C CA  . PHE A 1 326  ? 141.621 162.479 147.136 1.00 260.13 ? 344  PHE A CA  1 
ATOM   2456 C C   . PHE A 1 326  ? 141.687 163.822 146.427 1.00 259.93 ? 344  PHE A C   1 
ATOM   2457 O O   . PHE A 1 326  ? 141.940 164.851 147.064 1.00 259.98 ? 344  PHE A O   1 
ATOM   2458 C CB  . PHE A 1 326  ? 140.323 162.374 147.937 1.00 261.63 ? 344  PHE A CB  1 
ATOM   2459 C CG  . PHE A 1 326  ? 139.645 161.041 147.817 1.00 262.05 ? 344  PHE A CG  1 
ATOM   2460 C CD1 . PHE A 1 326  ? 138.921 160.719 146.681 1.00 258.85 ? 344  PHE A CD1 1 
ATOM   2461 C CD2 . PHE A 1 326  ? 139.730 160.111 148.837 1.00 263.95 ? 344  PHE A CD2 1 
ATOM   2462 C CE1 . PHE A 1 326  ? 138.294 159.495 146.567 1.00 258.54 ? 344  PHE A CE1 1 
ATOM   2463 C CE2 . PHE A 1 326  ? 139.105 158.884 148.727 1.00 264.37 ? 344  PHE A CE2 1 
ATOM   2464 C CZ  . PHE A 1 326  ? 138.387 158.576 147.591 1.00 260.68 ? 344  PHE A CZ  1 
ATOM   2465 N N   . LYS A 1 327  ? 141.456 163.804 145.117 1.00 259.58 ? 345  LYS A N   1 
ATOM   2466 C CA  . LYS A 1 327  ? 141.499 164.993 144.279 1.00 259.18 ? 345  LYS A CA  1 
ATOM   2467 C C   . LYS A 1 327  ? 140.103 165.299 143.757 1.00 258.48 ? 345  LYS A C   1 
ATOM   2468 O O   . LYS A 1 327  ? 139.372 164.396 143.337 1.00 258.09 ? 345  LYS A O   1 
ATOM   2469 C CB  . LYS A 1 327  ? 142.470 164.800 143.109 1.00 257.58 ? 345  LYS A CB  1 
ATOM   2470 C CG  . LYS A 1 327  ? 143.903 164.447 143.524 1.00 256.76 ? 345  LYS A CG  1 
ATOM   2471 C CD  . LYS A 1 327  ? 144.553 165.537 144.374 1.00 255.88 ? 345  LYS A CD  1 
ATOM   2472 C CE  . LYS A 1 327  ? 146.006 165.213 144.694 1.00 257.61 ? 345  LYS A CE  1 
ATOM   2473 N NZ  . LYS A 1 327  ? 146.610 166.215 145.618 1.00 257.14 ? 345  LYS A NZ  1 
ATOM   2474 N N   . GLN A 1 328  ? 139.742 166.580 143.787 1.00 259.04 ? 346  GLN A N   1 
ATOM   2475 C CA  . GLN A 1 328  ? 138.412 167.031 143.396 1.00 259.13 ? 346  GLN A CA  1 
ATOM   2476 C C   . GLN A 1 328  ? 138.254 167.212 141.891 1.00 259.84 ? 346  GLN A C   1 
ATOM   2477 O O   . GLN A 1 328  ? 137.161 167.581 141.448 1.00 258.48 ? 346  GLN A O   1 
ATOM   2478 C CB  . GLN A 1 328  ? 138.084 168.353 144.099 1.00 257.50 ? 346  GLN A CB  1 
ATOM   2479 C CG  . GLN A 1 328  ? 136.685 168.428 144.693 1.00 255.47 ? 346  GLN A CG  1 
ATOM   2480 C CD  . GLN A 1 328  ? 136.501 169.634 145.596 1.00 255.95 ? 346  GLN A CD  1 
ATOM   2481 O OE1 . GLN A 1 328  ? 137.424 170.423 145.795 1.00 256.13 ? 346  GLN A OE1 1 
ATOM   2482 N NE2 . GLN A 1 328  ? 135.301 169.783 146.145 1.00 255.56 ? 346  GLN A NE2 1 
ATOM   2483 N N   . HIS A 1 329  ? 139.299 166.962 141.104 1.00 260.50 ? 347  HIS A N   1 
ATOM   2484 C CA  . HIS A 1 329  ? 139.331 167.254 139.678 1.00 260.82 ? 347  HIS A CA  1 
ATOM   2485 C C   . HIS A 1 329  ? 139.654 165.994 138.886 1.00 262.63 ? 347  HIS A C   1 
ATOM   2486 O O   . HIS A 1 329  ? 140.158 165.002 139.420 1.00 261.72 ? 347  HIS A O   1 
ATOM   2487 C CB  . HIS A 1 329  ? 140.364 168.344 139.375 1.00 260.06 ? 347  HIS A CB  1 
ATOM   2488 C CG  . HIS A 1 329  ? 140.193 169.583 140.196 1.00 260.72 ? 347  HIS A CG  1 
ATOM   2489 N ND1 . HIS A 1 329  ? 141.191 170.083 141.004 1.00 261.78 ? 347  HIS A ND1 1 
ATOM   2490 C CD2 . HIS A 1 329  ? 139.141 170.424 140.333 1.00 259.45 ? 347  HIS A CD2 1 
ATOM   2491 C CE1 . HIS A 1 329  ? 140.761 171.178 141.605 1.00 259.95 ? 347  HIS A CE1 1 
ATOM   2492 N NE2 . HIS A 1 329  ? 139.520 171.407 141.215 1.00 259.76 ? 347  HIS A NE2 1 
ATOM   2493 N N   . ASP A 1 330  ? 139.347 166.049 137.588 1.00 265.97 ? 348  ASP A N   1 
ATOM   2494 C CA  . ASP A 1 330  ? 139.694 164.950 136.695 1.00 267.64 ? 348  ASP A CA  1 
ATOM   2495 C C   . ASP A 1 330  ? 141.204 164.778 136.604 1.00 266.25 ? 348  ASP A C   1 
ATOM   2496 O O   . ASP A 1 330  ? 141.707 163.648 136.584 1.00 264.59 ? 348  ASP A O   1 
ATOM   2497 C CB  . ASP A 1 330  ? 139.105 165.201 135.307 1.00 267.87 ? 348  ASP A CB  1 
ATOM   2498 C CG  . ASP A 1 330  ? 137.597 165.035 135.270 1.00 267.73 ? 348  ASP A CG  1 
ATOM   2499 O OD1 . ASP A 1 330  ? 137.074 164.125 135.946 1.00 268.76 ? 348  ASP A OD1 1 
ATOM   2500 O OD2 . ASP A 1 330  ? 136.933 165.821 134.561 1.00 265.15 ? 348  ASP A OD2 1 
ATOM   2501 N N   . TYR A 1 331  ? 141.936 165.888 136.535 1.00 265.78 ? 349  TYR A N   1 
ATOM   2502 C CA  . TYR A 1 331  ? 143.390 165.893 136.468 1.00 263.42 ? 349  TYR A CA  1 
ATOM   2503 C C   . TYR A 1 331  ? 143.904 166.944 137.439 1.00 263.32 ? 349  TYR A C   1 
ATOM   2504 O O   . TYR A 1 331  ? 143.148 167.798 137.909 1.00 263.72 ? 349  TYR A O   1 
ATOM   2505 C CB  . TYR A 1 331  ? 143.889 166.188 135.047 1.00 260.74 ? 349  TYR A CB  1 
ATOM   2506 C CG  . TYR A 1 331  ? 143.105 165.481 133.967 1.00 262.25 ? 349  TYR A CG  1 
ATOM   2507 C CD1 . TYR A 1 331  ? 143.203 164.107 133.798 1.00 262.38 ? 349  TYR A CD1 1 
ATOM   2508 C CD2 . TYR A 1 331  ? 142.265 166.186 133.118 1.00 263.82 ? 349  TYR A CD2 1 
ATOM   2509 C CE1 . TYR A 1 331  ? 142.487 163.456 132.814 1.00 265.28 ? 349  TYR A CE1 1 
ATOM   2510 C CE2 . TYR A 1 331  ? 141.546 165.544 132.129 1.00 266.32 ? 349  TYR A CE2 1 
ATOM   2511 C CZ  . TYR A 1 331  ? 141.661 164.178 131.982 1.00 267.98 ? 349  TYR A CZ  1 
ATOM   2512 O OH  . TYR A 1 331  ? 140.946 163.534 130.999 1.00 270.06 ? 349  TYR A OH  1 
ATOM   2513 N N   . ILE A 1 332  ? 145.201 166.875 137.737 1.00 261.01 ? 350  ILE A N   1 
ATOM   2514 C CA  . ILE A 1 332  ? 145.858 167.797 138.659 1.00 259.17 ? 350  ILE A CA  1 
ATOM   2515 C C   . ILE A 1 332  ? 146.939 168.543 137.890 1.00 260.54 ? 350  ILE A C   1 
ATOM   2516 O O   . ILE A 1 332  ? 147.724 167.934 137.148 1.00 261.78 ? 350  ILE A O   1 
ATOM   2517 C CB  . ILE A 1 332  ? 146.443 167.080 139.893 1.00 256.00 ? 350  ILE A CB  1 
ATOM   2518 C CG1 . ILE A 1 332  ? 147.273 165.851 139.498 1.00 258.41 ? 350  ILE A CG1 1 
ATOM   2519 C CG2 . ILE A 1 332  ? 145.317 166.677 140.855 1.00 253.66 ? 350  ILE A CG2 1 
ATOM   2520 C CD1 . ILE A 1 332  ? 147.853 165.085 140.674 1.00 256.63 ? 350  ILE A CD1 1 
ATOM   2521 N N   . ILE A 1 333  ? 146.969 169.863 138.072 1.00 260.42 ? 351  ILE A N   1 
ATOM   2522 C CA  . ILE A 1 333  ? 147.817 170.777 137.314 1.00 261.10 ? 351  ILE A CA  1 
ATOM   2523 C C   . ILE A 1 333  ? 148.687 171.536 138.305 1.00 260.50 ? 351  ILE A C   1 
ATOM   2524 O O   . ILE A 1 333  ? 148.194 171.999 139.340 1.00 257.01 ? 351  ILE A O   1 
ATOM   2525 C CB  . ILE A 1 333  ? 146.988 171.758 136.460 1.00 260.33 ? 351  ILE A CB  1 
ATOM   2526 C CG1 . ILE A 1 333  ? 146.046 171.029 135.486 1.00 260.38 ? 351  ILE A CG1 1 
ATOM   2527 C CG2 . ILE A 1 333  ? 147.907 172.696 135.686 1.00 258.91 ? 351  ILE A CG2 1 
ATOM   2528 C CD1 . ILE A 1 333  ? 144.832 171.845 135.093 1.00 255.12 ? 351  ILE A CD1 1 
ATOM   2529 N N   . GLU A 1 334  ? 149.976 171.658 137.988 1.00 261.68 ? 352  GLU A N   1 
ATOM   2530 C CA  . GLU A 1 334  ? 150.951 172.311 138.851 1.00 256.64 ? 352  GLU A CA  1 
ATOM   2531 C C   . GLU A 1 334  ? 151.828 173.242 138.027 1.00 252.45 ? 352  GLU A C   1 
ATOM   2532 O O   . GLU A 1 334  ? 152.059 173.012 136.836 1.00 254.21 ? 352  GLU A O   1 
ATOM   2533 C CB  . GLU A 1 334  ? 151.828 171.282 139.582 1.00 257.06 ? 352  GLU A CB  1 
ATOM   2534 C CG  . GLU A 1 334  ? 152.393 170.181 138.684 1.00 262.88 ? 352  GLU A CG  1 
ATOM   2535 C CD  . GLU A 1 334  ? 151.491 168.960 138.588 1.00 267.55 ? 352  GLU A CD  1 
ATOM   2536 O OE1 . GLU A 1 334  ? 150.290 169.065 138.916 1.00 267.86 ? 352  GLU A OE1 1 
ATOM   2537 O OE2 . GLU A 1 334  ? 151.988 167.889 138.181 1.00 268.80 ? 352  GLU A OE2 1 
ATOM   2538 N N   . PHE A 1 335  ? 152.319 174.293 138.685 1.00 245.82 ? 353  PHE A N   1 
ATOM   2539 C CA  . PHE A 1 335  ? 153.190 175.294 138.083 1.00 241.00 ? 353  PHE A CA  1 
ATOM   2540 C C   . PHE A 1 335  ? 154.527 175.305 138.808 1.00 235.92 ? 353  PHE A C   1 
ATOM   2541 O O   . PHE A 1 335  ? 154.591 175.051 140.015 1.00 233.29 ? 353  PHE A O   1 
ATOM   2542 C CB  . PHE A 1 335  ? 152.574 176.699 138.160 1.00 240.01 ? 353  PHE A CB  1 
ATOM   2543 C CG  . PHE A 1 335  ? 151.188 176.800 137.585 1.00 244.36 ? 353  PHE A CG  1 
ATOM   2544 C CD1 . PHE A 1 335  ? 150.848 176.142 136.416 1.00 248.58 ? 353  PHE A CD1 1 
ATOM   2545 C CD2 . PHE A 1 335  ? 150.226 177.572 138.216 1.00 241.13 ? 353  PHE A CD2 1 
ATOM   2546 C CE1 . PHE A 1 335  ? 149.574 176.246 135.892 1.00 250.19 ? 353  PHE A CE1 1 
ATOM   2547 C CE2 . PHE A 1 335  ? 148.951 177.678 137.697 1.00 241.17 ? 353  PHE A CE2 1 
ATOM   2548 C CZ  . PHE A 1 335  ? 148.625 177.015 136.533 1.00 247.05 ? 353  PHE A CZ  1 
ATOM   2549 N N   . PHE A 1 336  ? 155.595 175.598 138.069 1.00 234.17 ? 354  PHE A N   1 
ATOM   2550 C CA  . PHE A 1 336  ? 156.901 175.821 138.675 1.00 231.79 ? 354  PHE A CA  1 
ATOM   2551 C C   . PHE A 1 336  ? 157.716 176.718 137.748 1.00 232.59 ? 354  PHE A C   1 
ATOM   2552 O O   . PHE A 1 336  ? 157.274 177.085 136.655 1.00 232.35 ? 354  PHE A O   1 
ATOM   2553 C CB  . PHE A 1 336  ? 157.613 174.494 138.983 1.00 231.47 ? 354  PHE A CB  1 
ATOM   2554 C CG  . PHE A 1 336  ? 157.237 173.366 138.070 1.00 232.75 ? 354  PHE A CG  1 
ATOM   2555 C CD1 . PHE A 1 336  ? 157.893 173.191 136.868 1.00 234.18 ? 354  PHE A CD1 1 
ATOM   2556 C CD2 . PHE A 1 336  ? 156.244 172.469 138.423 1.00 234.06 ? 354  PHE A CD2 1 
ATOM   2557 C CE1 . PHE A 1 336  ? 157.558 172.152 136.024 1.00 235.86 ? 354  PHE A CE1 1 
ATOM   2558 C CE2 . PHE A 1 336  ? 155.904 171.429 137.584 1.00 238.17 ? 354  PHE A CE2 1 
ATOM   2559 C CZ  . PHE A 1 336  ? 156.565 171.270 136.383 1.00 239.12 ? 354  PHE A CZ  1 
ATOM   2560 N N   . ASP A 1 337  ? 158.908 177.097 138.214 1.00 232.51 ? 355  ASP A N   1 
ATOM   2561 C CA  . ASP A 1 337  ? 159.820 177.953 137.456 1.00 233.20 ? 355  ASP A CA  1 
ATOM   2562 C C   . ASP A 1 337  ? 159.192 179.319 137.179 1.00 228.59 ? 355  ASP A C   1 
ATOM   2563 O O   . ASP A 1 337  ? 159.243 179.835 136.060 1.00 227.52 ? 355  ASP A O   1 
ATOM   2564 C CB  . ASP A 1 337  ? 160.250 177.275 136.152 1.00 237.63 ? 355  ASP A CB  1 
ATOM   2565 C CG  . ASP A 1 337  ? 160.527 175.796 136.327 1.00 239.58 ? 355  ASP A CG  1 
ATOM   2566 O OD1 . ASP A 1 337  ? 161.076 175.413 137.381 1.00 243.13 ? 355  ASP A OD1 1 
ATOM   2567 O OD2 . ASP A 1 337  ? 160.197 175.016 135.409 1.00 238.99 ? 355  ASP A OD2 1 
ATOM   2568 N N   . TYR A 1 338  ? 158.601 179.906 138.220 1.00 227.15 ? 356  TYR A N   1 
ATOM   2569 C CA  . TYR A 1 338  ? 158.004 181.233 138.159 1.00 226.29 ? 356  TYR A CA  1 
ATOM   2570 C C   . TYR A 1 338  ? 158.671 182.141 139.182 1.00 225.32 ? 356  TYR A C   1 
ATOM   2571 O O   . TYR A 1 338  ? 159.057 181.702 140.269 1.00 221.52 ? 356  TYR A O   1 
ATOM   2572 C CB  . TYR A 1 338  ? 156.487 181.192 138.416 1.00 224.44 ? 356  TYR A CB  1 
ATOM   2573 C CG  . TYR A 1 338  ? 156.060 180.383 139.623 1.00 223.15 ? 356  TYR A CG  1 
ATOM   2574 C CD1 . TYR A 1 338  ? 156.124 180.920 140.903 1.00 221.43 ? 356  TYR A CD1 1 
ATOM   2575 C CD2 . TYR A 1 338  ? 155.574 179.091 139.481 1.00 223.55 ? 356  TYR A CD2 1 
ATOM   2576 C CE1 . TYR A 1 338  ? 155.730 180.189 142.005 1.00 219.72 ? 356  TYR A CE1 1 
ATOM   2577 C CE2 . TYR A 1 338  ? 155.174 178.355 140.579 1.00 222.98 ? 356  TYR A CE2 1 
ATOM   2578 C CZ  . TYR A 1 338  ? 155.256 178.907 141.837 1.00 220.53 ? 356  TYR A CZ  1 
ATOM   2579 O OH  . TYR A 1 338  ? 154.861 178.175 142.933 1.00 217.57 ? 356  TYR A OH  1 
ATOM   2580 N N   . THR A 1 339  ? 158.803 183.414 138.822 1.00 226.24 ? 357  THR A N   1 
ATOM   2581 C CA  . THR A 1 339  ? 159.381 184.399 139.725 1.00 226.65 ? 357  THR A CA  1 
ATOM   2582 C C   . THR A 1 339  ? 158.352 184.794 140.776 1.00 229.66 ? 357  THR A C   1 
ATOM   2583 O O   . THR A 1 339  ? 157.209 185.123 140.447 1.00 231.22 ? 357  THR A O   1 
ATOM   2584 C CB  . THR A 1 339  ? 159.852 185.636 138.956 1.00 224.71 ? 357  THR A CB  1 
ATOM   2585 O OG1 . THR A 1 339  ? 158.720 186.415 138.548 1.00 224.28 ? 357  THR A OG1 1 
ATOM   2586 C CG2 . THR A 1 339  ? 160.673 185.241 137.732 1.00 217.26 ? 357  THR A CG2 1 
ATOM   2587 N N   . THR A 1 340  ? 158.763 184.762 142.043 1.00 230.67 ? 358  THR A N   1 
ATOM   2588 C CA  . THR A 1 340  ? 157.873 185.120 143.139 1.00 234.02 ? 358  THR A CA  1 
ATOM   2589 C C   . THR A 1 340  ? 157.593 186.616 143.225 1.00 233.27 ? 358  THR A C   1 
ATOM   2590 O O   . THR A 1 340  ? 156.698 187.010 143.981 1.00 233.68 ? 358  THR A O   1 
ATOM   2591 C CB  . THR A 1 340  ? 158.461 184.642 144.469 1.00 235.47 ? 358  THR A CB  1 
ATOM   2592 O OG1 . THR A 1 340  ? 159.716 185.293 144.703 1.00 236.43 ? 358  THR A OG1 1 
ATOM   2593 C CG2 . THR A 1 340  ? 158.665 183.133 144.454 1.00 231.24 ? 358  THR A CG2 1 
ATOM   2594 N N   . VAL A 1 341  ? 158.322 187.448 142.481 1.00 230.46 ? 359  VAL A N   1 
ATOM   2595 C CA  . VAL A 1 341  ? 158.156 188.898 142.490 1.00 225.94 ? 359  VAL A CA  1 
ATOM   2596 C C   . VAL A 1 341  ? 157.878 189.353 141.065 1.00 222.31 ? 359  VAL A C   1 
ATOM   2597 O O   . VAL A 1 341  ? 158.541 188.904 140.123 1.00 218.24 ? 359  VAL A O   1 
ATOM   2598 C CB  . VAL A 1 341  ? 159.392 189.615 143.073 1.00 223.49 ? 359  VAL A CB  1 
ATOM   2599 C CG1 . VAL A 1 341  ? 160.695 189.086 142.461 1.00 218.53 ? 359  VAL A CG1 1 
ATOM   2600 C CG2 . VAL A 1 341  ? 159.276 191.123 142.882 1.00 216.59 ? 359  VAL A CG2 1 
ATOM   2601 N N   . LEU A 1 342  ? 156.891 190.230 140.910 1.00 221.05 ? 360  LEU A N   1 
ATOM   2602 C CA  . LEU A 1 342  ? 156.511 190.703 139.585 1.00 217.41 ? 360  LEU A CA  1 
ATOM   2603 C C   . LEU A 1 342  ? 157.591 191.616 139.017 1.00 209.71 ? 360  LEU A C   1 
ATOM   2604 O O   . LEU A 1 342  ? 158.123 192.481 139.719 1.00 209.60 ? 360  LEU A O   1 
ATOM   2605 C CB  . LEU A 1 342  ? 155.172 191.444 139.639 1.00 219.37 ? 360  LEU A CB  1 
ATOM   2606 C CG  . LEU A 1 342  ? 153.902 190.688 139.228 1.00 224.35 ? 360  LEU A CG  1 
ATOM   2607 C CD1 . LEU A 1 342  ? 152.682 191.576 139.420 1.00 225.12 ? 360  LEU A CD1 1 
ATOM   2608 C CD2 . LEU A 1 342  ? 153.971 190.203 137.783 1.00 224.91 ? 360  LEU A CD2 1 
ATOM   2609 N N   . LYS A 1 343  ? 157.907 191.413 137.740 1.00 202.39 ? 361  LYS A N   1 
ATOM   2610 C CA  . LYS A 1 343  ? 158.881 192.222 137.005 1.00 198.53 ? 361  LYS A CA  1 
ATOM   2611 C C   . LYS A 1 343  ? 158.193 192.764 135.756 1.00 198.36 ? 361  LYS A C   1 
ATOM   2612 O O   . LYS A 1 343  ? 158.192 192.089 134.711 1.00 201.59 ? 361  LYS A O   1 
ATOM   2613 C CB  . LYS A 1 343  ? 160.107 191.391 136.631 1.00 195.29 ? 361  LYS A CB  1 
ATOM   2614 C CG  . LYS A 1 343  ? 160.879 190.841 137.828 1.00 196.55 ? 361  LYS A CG  1 
ATOM   2615 C CD  . LYS A 1 343  ? 161.675 191.928 138.537 1.00 193.67 ? 361  LYS A CD  1 
ATOM   2616 C CE  . LYS A 1 343  ? 162.638 191.337 139.554 1.00 185.68 ? 361  LYS A CE  1 
ATOM   2617 N NZ  . LYS A 1 343  ? 163.419 192.389 140.263 1.00 176.45 ? 361  LYS A NZ  1 
ATOM   2618 N N   . PRO A 1 344  ? 157.583 193.953 135.801 1.00 197.49 ? 362  PRO A N   1 
ATOM   2619 C CA  . PRO A 1 344  ? 156.797 194.415 134.650 1.00 203.13 ? 362  PRO A CA  1 
ATOM   2620 C C   . PRO A 1 344  ? 157.652 194.670 133.417 1.00 203.08 ? 362  PRO A C   1 
ATOM   2621 O O   . PRO A 1 344  ? 158.858 194.912 133.490 1.00 200.50 ? 362  PRO A O   1 
ATOM   2622 C CB  . PRO A 1 344  ? 156.156 195.717 135.146 1.00 207.77 ? 362  PRO A CB  1 
ATOM   2623 C CG  . PRO A 1 344  ? 156.253 195.674 136.617 1.00 206.46 ? 362  PRO A CG  1 
ATOM   2624 C CD  . PRO A 1 344  ? 157.487 194.903 136.925 1.00 198.91 ? 362  PRO A CD  1 
ATOM   2625 N N   . SER A 1 345  ? 156.987 194.604 132.263 1.00 207.45 ? 363  SER A N   1 
ATOM   2626 C CA  . SER A 1 345  ? 157.600 194.884 130.964 1.00 206.91 ? 363  SER A CA  1 
ATOM   2627 C C   . SER A 1 345  ? 158.675 193.862 130.601 1.00 201.50 ? 363  SER A C   1 
ATOM   2628 O O   . SER A 1 345  ? 159.591 194.166 129.833 1.00 199.80 ? 363  SER A O   1 
ATOM   2629 C CB  . SER A 1 345  ? 158.185 196.299 130.924 1.00 207.09 ? 363  SER A CB  1 
ATOM   2630 O OG  . SER A 1 345  ? 159.473 196.340 131.515 1.00 204.51 ? 363  SER A OG  1 
ATOM   2631 N N   . LEU A 1 346  ? 158.565 192.678 131.208 1.00 200.61 ? 364  LEU A N   1 
ATOM   2632 C CA  . LEU A 1 346  ? 159.560 191.592 131.024 1.00 196.41 ? 364  LEU A CA  1 
ATOM   2633 C C   . LEU A 1 346  ? 158.812 190.266 130.869 1.00 196.32 ? 364  LEU A C   1 
ATOM   2634 O O   . LEU A 1 346  ? 158.161 189.836 131.838 1.00 198.53 ? 364  LEU A O   1 
ATOM   2635 C CB  . LEU A 1 346  ? 160.494 191.554 132.236 1.00 197.80 ? 364  LEU A CB  1 
ATOM   2636 C CG  . LEU A 1 346  ? 161.877 192.173 132.033 1.00 190.91 ? 364  LEU A CG  1 
ATOM   2637 C CD1 . LEU A 1 346  ? 162.401 191.896 130.633 1.00 181.37 ? 364  LEU A CD1 1 
ATOM   2638 C CD2 . LEU A 1 346  ? 161.861 193.668 132.313 1.00 191.19 ? 364  LEU A CD2 1 
ATOM   2639 N N   . ASN A 1 347  ? 158.915 189.660 129.689 1.00 194.58 ? 365  ASN A N   1 
ATOM   2640 C CA  . ASN A 1 347  ? 158.241 188.370 129.401 1.00 200.79 ? 365  ASN A CA  1 
ATOM   2641 C C   . ASN A 1 347  ? 158.282 187.477 130.640 1.00 202.11 ? 365  ASN A C   1 
ATOM   2642 O O   . ASN A 1 347  ? 159.387 187.085 131.050 1.00 200.19 ? 365  ASN A O   1 
ATOM   2643 C CB  . ASN A 1 347  ? 158.884 187.679 128.202 1.00 206.05 ? 365  ASN A CB  1 
ATOM   2644 C CG  . ASN A 1 347  ? 158.173 188.005 126.910 1.00 212.92 ? 365  ASN A CG  1 
ATOM   2645 O OD1 . ASN A 1 347  ? 157.920 189.168 126.608 1.00 211.46 ? 365  ASN A OD1 1 
ATOM   2646 N ND2 . ASN A 1 347  ? 157.844 186.979 126.148 1.00 222.42 ? 365  ASN A ND2 1 
ATOM   2647 N N   . PHE A 1 348  ? 157.113 187.158 131.194 1.00 205.26 ? 366  PHE A N   1 
ATOM   2648 C CA  . PHE A 1 348  ? 157.026 186.139 132.269 1.00 206.19 ? 366  PHE A CA  1 
ATOM   2649 C C   . PHE A 1 348  ? 157.050 184.738 131.653 1.00 210.29 ? 366  PHE A C   1 
ATOM   2650 O O   . PHE A 1 348  ? 156.392 184.525 130.618 1.00 213.01 ? 366  PHE A O   1 
ATOM   2651 C CB  . PHE A 1 348  ? 155.743 186.308 133.080 1.00 208.71 ? 366  PHE A CB  1 
ATOM   2652 C CG  . PHE A 1 348  ? 155.604 185.298 134.188 1.00 210.11 ? 366  PHE A CG  1 
ATOM   2653 C CD1 . PHE A 1 348  ? 156.492 185.289 135.251 1.00 213.50 ? 366  PHE A CD1 1 
ATOM   2654 C CD2 . PHE A 1 348  ? 154.619 184.327 134.142 1.00 211.85 ? 366  PHE A CD2 1 
ATOM   2655 C CE1 . PHE A 1 348  ? 156.373 184.351 136.262 1.00 217.85 ? 366  PHE A CE1 1 
ATOM   2656 C CE2 . PHE A 1 348  ? 154.501 183.389 135.153 1.00 214.34 ? 366  PHE A CE2 1 
ATOM   2657 C CZ  . PHE A 1 348  ? 155.377 183.405 136.210 1.00 216.95 ? 366  PHE A CZ  1 
ATOM   2658 N N   . THR A 1 349  ? 157.776 183.816 132.290 1.00 211.18 ? 367  THR A N   1 
ATOM   2659 C CA  . THR A 1 349  ? 157.841 182.432 131.843 1.00 217.94 ? 367  THR A CA  1 
ATOM   2660 C C   . THR A 1 349  ? 157.625 181.513 133.034 1.00 220.36 ? 367  THR A C   1 
ATOM   2661 O O   . THR A 1 349  ? 158.159 181.761 134.119 1.00 220.90 ? 367  THR A O   1 
ATOM   2662 C CB  . THR A 1 349  ? 159.188 182.125 131.179 1.00 220.79 ? 367  THR A CB  1 
ATOM   2663 O OG1 . THR A 1 349  ? 159.534 183.186 130.281 1.00 221.22 ? 367  THR A OG1 1 
ATOM   2664 C CG2 . THR A 1 349  ? 159.122 180.812 130.408 1.00 224.14 ? 367  THR A CG2 1 
ATOM   2665 N N   . ALA A 1 350  ? 156.838 180.460 132.825 1.00 221.93 ? 368  ALA A N   1 
ATOM   2666 C CA  . ALA A 1 350  ? 156.612 179.427 133.825 1.00 224.88 ? 368  ALA A CA  1 
ATOM   2667 C C   . ALA A 1 350  ? 156.543 178.088 133.107 1.00 226.43 ? 368  ALA A C   1 
ATOM   2668 O O   . ALA A 1 350  ? 156.599 178.025 131.876 1.00 224.20 ? 368  ALA A O   1 
ATOM   2669 C CB  . ALA A 1 350  ? 155.337 179.701 134.630 1.00 225.65 ? 368  ALA A CB  1 
ATOM   2670 N N   . THR A 1 351  ? 156.417 177.008 133.879 1.00 230.27 ? 369  THR A N   1 
ATOM   2671 C CA  . THR A 1 351  ? 156.294 175.663 133.334 1.00 235.89 ? 369  THR A CA  1 
ATOM   2672 C C   . THR A 1 351  ? 155.148 174.952 134.033 1.00 238.66 ? 369  THR A C   1 
ATOM   2673 O O   . THR A 1 351  ? 155.065 174.958 135.267 1.00 236.84 ? 369  THR A O   1 
ATOM   2674 C CB  . THR A 1 351  ? 157.596 174.876 133.501 1.00 237.86 ? 369  THR A CB  1 
ATOM   2675 O OG1 . THR A 1 351  ? 158.713 175.738 133.250 1.00 238.98 ? 369  THR A OG1 1 
ATOM   2676 C CG2 . THR A 1 351  ? 157.638 173.698 132.539 1.00 239.85 ? 369  THR A CG2 1 
ATOM   2677 N N   . VAL A 1 352  ? 154.278 174.334 133.236 1.00 244.42 ? 370  VAL A N   1 
ATOM   2678 C CA  . VAL A 1 352  ? 153.043 173.716 133.699 1.00 249.87 ? 370  VAL A CA  1 
ATOM   2679 C C   . VAL A 1 352  ? 153.144 172.217 133.464 1.00 253.68 ? 370  VAL A C   1 
ATOM   2680 O O   . VAL A 1 352  ? 153.578 171.779 132.389 1.00 252.97 ? 370  VAL A O   1 
ATOM   2681 C CB  . VAL A 1 352  ? 151.815 174.296 132.971 1.00 250.29 ? 370  VAL A CB  1 
ATOM   2682 C CG1 . VAL A 1 352  ? 150.520 173.774 133.597 1.00 252.26 ? 370  VAL A CG1 1 
ATOM   2683 C CG2 . VAL A 1 352  ? 151.867 175.822 132.970 1.00 249.25 ? 370  VAL A CG2 1 
ATOM   2684 N N   . LYS A 1 353  ? 152.751 171.440 134.474 1.00 257.90 ? 371  LYS A N   1 
ATOM   2685 C CA  . LYS A 1 353  ? 152.663 169.986 134.393 1.00 261.65 ? 371  LYS A CA  1 
ATOM   2686 C C   . LYS A 1 353  ? 151.243 169.567 134.739 1.00 263.61 ? 371  LYS A C   1 
ATOM   2687 O O   . LYS A 1 353  ? 150.723 169.943 135.794 1.00 264.98 ? 371  LYS A O   1 
ATOM   2688 C CB  . LYS A 1 353  ? 153.654 169.316 135.346 1.00 262.52 ? 371  LYS A CB  1 
ATOM   2689 C CG  . LYS A 1 353  ? 154.758 168.532 134.653 1.00 261.81 ? 371  LYS A CG  1 
ATOM   2690 C CD  . LYS A 1 353  ? 155.558 167.679 135.641 1.00 261.35 ? 371  LYS A CD  1 
ATOM   2691 C CE  . LYS A 1 353  ? 154.832 166.405 136.079 1.00 264.31 ? 371  LYS A CE  1 
ATOM   2692 N NZ  . LYS A 1 353  ? 154.411 165.525 134.950 1.00 261.07 ? 371  LYS A NZ  1 
ATOM   2693 N N   . VAL A 1 354  ? 150.628 168.782 133.858 1.00 264.40 ? 372  VAL A N   1 
ATOM   2694 C CA  . VAL A 1 354  ? 149.294 168.230 134.061 1.00 264.09 ? 372  VAL A CA  1 
ATOM   2695 C C   . VAL A 1 354  ? 149.426 166.716 134.097 1.00 264.43 ? 372  VAL A C   1 
ATOM   2696 O O   . VAL A 1 354  ? 150.036 166.126 133.198 1.00 264.37 ? 372  VAL A O   1 
ATOM   2697 C CB  . VAL A 1 354  ? 148.324 168.666 132.948 1.00 263.68 ? 372  VAL A CB  1 
ATOM   2698 C CG1 . VAL A 1 354  ? 146.889 168.254 133.291 1.00 262.50 ? 372  VAL A CG1 1 
ATOM   2699 C CG2 . VAL A 1 354  ? 148.445 170.168 132.699 1.00 261.36 ? 372  VAL A CG2 1 
ATOM   2700 N N   . THR A 1 355  ? 148.867 166.092 135.135 1.00 263.36 ? 373  THR A N   1 
ATOM   2701 C CA  . THR A 1 355  ? 148.911 164.640 135.261 1.00 263.65 ? 373  THR A CA  1 
ATOM   2702 C C   . THR A 1 355  ? 147.569 164.133 135.769 1.00 263.42 ? 373  THR A C   1 
ATOM   2703 O O   . THR A 1 355  ? 146.722 164.896 136.241 1.00 260.74 ? 373  THR A O   1 
ATOM   2704 C CB  . THR A 1 355  ? 150.056 164.162 136.177 1.00 262.44 ? 373  THR A CB  1 
ATOM   2705 O OG1 . THR A 1 355  ? 150.007 162.734 136.293 1.00 264.40 ? 373  THR A OG1 1 
ATOM   2706 C CG2 . THR A 1 355  ? 149.970 164.769 137.568 1.00 260.60 ? 373  THR A CG2 1 
ATOM   2707 N N   . ARG A 1 356  ? 147.384 162.823 135.640 1.00 265.39 ? 374  ARG A N   1 
ATOM   2708 C CA  . ARG A 1 356  ? 146.083 162.207 135.836 1.00 265.81 ? 374  ARG A CA  1 
ATOM   2709 C C   . ARG A 1 356  ? 145.803 161.986 137.322 1.00 267.62 ? 374  ARG A C   1 
ATOM   2710 O O   . ARG A 1 356  ? 146.708 161.948 138.160 1.00 267.02 ? 374  ARG A O   1 
ATOM   2711 C CB  . ARG A 1 356  ? 146.002 160.883 135.072 1.00 266.59 ? 374  ARG A CB  1 
ATOM   2712 C CG  . ARG A 1 356  ? 144.789 160.756 134.145 1.00 264.44 ? 374  ARG A CG  1 
ATOM   2713 C CD  . ARG A 1 356  ? 144.980 159.692 133.066 1.00 267.86 ? 374  ARG A CD  1 
ATOM   2714 N NE  . ARG A 1 356  ? 144.649 158.354 133.545 1.00 269.29 ? 374  ARG A NE  1 
ATOM   2715 C CZ  . ARG A 1 356  ? 144.839 157.232 132.862 1.00 268.39 ? 374  ARG A CZ  1 
ATOM   2716 N NH1 . ARG A 1 356  ? 145.371 157.234 131.648 1.00 266.54 ? 374  ARG A NH1 1 
ATOM   2717 N NH2 . ARG A 1 356  ? 144.489 156.073 133.412 1.00 267.49 ? 374  ARG A NH2 1 
ATOM   2718 N N   . ALA A 1 357  ? 144.514 161.842 137.639 1.00 268.89 ? 375  ALA A N   1 
ATOM   2719 C CA  . ALA A 1 357  ? 144.102 161.663 139.028 1.00 269.84 ? 375  ALA A CA  1 
ATOM   2720 C C   . ALA A 1 357  ? 144.633 160.356 139.603 1.00 270.17 ? 375  ALA A C   1 
ATOM   2721 O O   . ALA A 1 357  ? 145.075 160.316 140.757 1.00 268.25 ? 375  ALA A O   1 
ATOM   2722 C CB  . ALA A 1 357  ? 142.578 161.710 139.131 1.00 266.03 ? 375  ALA A CB  1 
ATOM   2723 N N   . ASP A 1 358  ? 144.598 159.279 138.820 1.00 272.88 ? 376  ASP A N   1 
ATOM   2724 C CA  . ASP A 1 358  ? 145.083 157.984 139.285 1.00 273.53 ? 376  ASP A CA  1 
ATOM   2725 C C   . ASP A 1 358  ? 146.598 157.842 139.185 1.00 274.83 ? 376  ASP A C   1 
ATOM   2726 O O   . ASP A 1 358  ? 147.128 156.793 139.569 1.00 274.99 ? 376  ASP A O   1 
ATOM   2727 C CB  . ASP A 1 358  ? 144.412 156.845 138.503 1.00 275.53 ? 376  ASP A CB  1 
ATOM   2728 C CG  . ASP A 1 358  ? 144.672 156.917 137.008 1.00 276.12 ? 376  ASP A CG  1 
ATOM   2729 O OD1 . ASP A 1 358  ? 145.228 157.931 136.542 1.00 275.50 ? 376  ASP A OD1 1 
ATOM   2730 O OD2 . ASP A 1 358  ? 144.319 155.952 136.297 1.00 275.96 ? 376  ASP A OD2 1 
ATOM   2731 N N   . GLY A 1 359  ? 147.306 158.854 138.683 1.00 274.41 ? 377  GLY A N   1 
ATOM   2732 C CA  . GLY A 1 359  ? 148.746 158.795 138.557 1.00 275.40 ? 377  GLY A CA  1 
ATOM   2733 C C   . GLY A 1 359  ? 149.258 158.099 137.315 1.00 277.12 ? 377  GLY A C   1 
ATOM   2734 O O   . GLY A 1 359  ? 150.480 158.001 137.144 1.00 277.60 ? 377  GLY A O   1 
ATOM   2735 N N   . ASN A 1 360  ? 148.375 157.614 136.445 1.00 277.28 ? 378  ASN A N   1 
ATOM   2736 C CA  . ASN A 1 360  ? 148.800 156.943 135.229 1.00 275.42 ? 378  ASN A CA  1 
ATOM   2737 C C   . ASN A 1 360  ? 149.171 157.966 134.157 1.00 274.00 ? 378  ASN A C   1 
ATOM   2738 O O   . ASN A 1 360  ? 148.890 159.162 134.269 1.00 272.10 ? 378  ASN A O   1 
ATOM   2739 C CB  . ASN A 1 360  ? 147.699 156.013 134.722 1.00 275.77 ? 378  ASN A CB  1 
ATOM   2740 C CG  . ASN A 1 360  ? 147.489 154.814 135.625 1.00 276.47 ? 378  ASN A CG  1 
ATOM   2741 O OD1 . ASN A 1 360  ? 148.444 154.246 136.154 1.00 275.82 ? 378  ASN A OD1 1 
ATOM   2742 N ND2 . ASN A 1 360  ? 146.234 154.421 135.805 1.00 277.39 ? 378  ASN A ND2 1 
ATOM   2743 N N   . GLN A 1 361  ? 149.813 157.473 133.102 1.00 273.99 ? 379  GLN A N   1 
ATOM   2744 C CA  . GLN A 1 361  ? 150.269 158.343 132.027 1.00 275.84 ? 379  GLN A CA  1 
ATOM   2745 C C   . GLN A 1 361  ? 149.080 158.898 131.253 1.00 276.22 ? 379  GLN A C   1 
ATOM   2746 O O   . GLN A 1 361  ? 148.095 158.197 131.006 1.00 274.22 ? 379  GLN A O   1 
ATOM   2747 C CB  . GLN A 1 361  ? 151.199 157.572 131.086 1.00 275.27 ? 379  GLN A CB  1 
ATOM   2748 C CG  . GLN A 1 361  ? 152.323 158.394 130.464 1.00 275.63 ? 379  GLN A CG  1 
ATOM   2749 C CD  . GLN A 1 361  ? 151.918 159.038 129.156 1.00 278.87 ? 379  GLN A CD  1 
ATOM   2750 O OE1 . GLN A 1 361  ? 151.536 158.354 128.206 1.00 277.93 ? 379  GLN A OE1 1 
ATOM   2751 N NE2 . GLN A 1 361  ? 152.011 160.361 129.093 1.00 280.78 ? 379  GLN A NE2 1 
ATOM   2752 N N   . LEU A 1 362  ? 149.175 160.169 130.869 1.00 277.28 ? 380  LEU A N   1 
ATOM   2753 C CA  . LEU A 1 362  ? 148.096 160.808 130.130 1.00 276.87 ? 380  LEU A CA  1 
ATOM   2754 C C   . LEU A 1 362  ? 148.001 160.238 128.718 1.00 279.08 ? 380  LEU A C   1 
ATOM   2755 O O   . LEU A 1 362  ? 149.000 159.841 128.112 1.00 279.03 ? 380  LEU A O   1 
ATOM   2756 C CB  . LEU A 1 362  ? 148.304 162.324 130.087 1.00 276.32 ? 380  LEU A CB  1 
ATOM   2757 C CG  . LEU A 1 362  ? 149.456 162.869 129.238 1.00 276.04 ? 380  LEU A CG  1 
ATOM   2758 C CD1 . LEU A 1 362  ? 148.939 163.492 127.952 1.00 275.38 ? 380  LEU A CD1 1 
ATOM   2759 C CD2 . LEU A 1 362  ? 150.269 163.878 130.034 1.00 273.60 ? 380  LEU A CD2 1 
ATOM   2760 N N   . THR A 1 363  ? 146.777 160.204 128.196 1.00 279.99 ? 381  THR A N   1 
ATOM   2761 C CA  . THR A 1 363  ? 146.495 159.550 126.929 1.00 280.50 ? 381  THR A CA  1 
ATOM   2762 C C   . THR A 1 363  ? 146.732 160.500 125.756 1.00 280.48 ? 381  THR A C   1 
ATOM   2763 O O   . THR A 1 363  ? 146.767 161.725 125.902 1.00 281.81 ? 381  THR A O   1 
ATOM   2764 C CB  . THR A 1 363  ? 145.054 159.041 126.896 1.00 281.23 ? 381  THR A CB  1 
ATOM   2765 O OG1 . THR A 1 363  ? 144.161 160.140 126.671 1.00 284.52 ? 381  THR A OG1 1 
ATOM   2766 C CG2 . THR A 1 363  ? 144.689 158.351 128.205 1.00 276.42 ? 381  THR A CG2 1 
ATOM   2767 N N   . LEU A 1 364  ? 146.892 159.909 124.569 1.00 278.45 ? 382  LEU A N   1 
ATOM   2768 C CA  . LEU A 1 364  ? 146.999 160.698 123.347 1.00 277.40 ? 382  LEU A CA  1 
ATOM   2769 C C   . LEU A 1 364  ? 145.722 161.472 123.053 1.00 279.91 ? 382  LEU A C   1 
ATOM   2770 O O   . LEU A 1 364  ? 145.789 162.540 122.435 1.00 280.17 ? 382  LEU A O   1 
ATOM   2771 C CB  . LEU A 1 364  ? 147.330 159.795 122.152 1.00 274.41 ? 382  LEU A CB  1 
ATOM   2772 C CG  . LEU A 1 364  ? 148.796 159.549 121.770 1.00 271.03 ? 382  LEU A CG  1 
ATOM   2773 C CD1 . LEU A 1 364  ? 149.534 160.842 121.440 1.00 271.14 ? 382  LEU A CD1 1 
ATOM   2774 C CD2 . LEU A 1 364  ? 149.513 158.794 122.877 1.00 271.07 ? 382  LEU A CD2 1 
ATOM   2775 N N   . GLU A 1 365  ? 144.565 160.952 123.469 1.00 281.87 ? 383  GLU A N   1 
ATOM   2776 C CA  . GLU A 1 365  ? 143.312 161.673 123.267 1.00 281.45 ? 383  GLU A CA  1 
ATOM   2777 C C   . GLU A 1 365  ? 143.314 162.992 124.029 1.00 282.34 ? 383  GLU A C   1 
ATOM   2778 O O   . GLU A 1 365  ? 142.853 164.016 123.512 1.00 280.78 ? 383  GLU A O   1 
ATOM   2779 C CB  . GLU A 1 365  ? 142.136 160.795 123.700 1.00 279.87 ? 383  GLU A CB  1 
ATOM   2780 C CG  . GLU A 1 365  ? 140.775 161.504 123.730 1.00 278.07 ? 383  GLU A CG  1 
ATOM   2781 C CD  . GLU A 1 365  ? 140.381 162.030 125.106 1.00 277.19 ? 383  GLU A CD  1 
ATOM   2782 O OE1 . GLU A 1 365  ? 140.679 161.372 126.126 1.00 276.59 ? 383  GLU A OE1 1 
ATOM   2783 O OE2 . GLU A 1 365  ? 139.770 163.117 125.165 1.00 274.44 ? 383  GLU A OE2 1 
ATOM   2784 N N   . GLU A 1 366  ? 143.828 162.986 125.260 1.00 284.20 ? 384  GLU A N   1 
ATOM   2785 C CA  . GLU A 1 366  ? 143.898 164.209 126.049 1.00 280.94 ? 384  GLU A CA  1 
ATOM   2786 C C   . GLU A 1 366  ? 144.845 165.235 125.441 1.00 279.29 ? 384  GLU A C   1 
ATOM   2787 O O   . GLU A 1 366  ? 144.664 166.436 125.670 1.00 276.82 ? 384  GLU A O   1 
ATOM   2788 C CB  . GLU A 1 366  ? 144.335 163.883 127.478 1.00 279.14 ? 384  GLU A CB  1 
ATOM   2789 C CG  . GLU A 1 366  ? 143.313 163.054 128.270 1.00 277.47 ? 384  GLU A CG  1 
ATOM   2790 C CD  . GLU A 1 366  ? 143.924 162.189 129.368 1.00 275.80 ? 384  GLU A CD  1 
ATOM   2791 O OE1 . GLU A 1 366  ? 145.128 161.861 129.306 1.00 276.31 ? 384  GLU A OE1 1 
ATOM   2792 O OE2 . GLU A 1 366  ? 143.183 161.828 130.305 1.00 273.47 ? 384  GLU A OE2 1 
ATOM   2793 N N   . ARG A 1 367  ? 145.844 164.795 124.673 1.00 280.85 ? 385  ARG A N   1 
ATOM   2794 C CA  . ARG A 1 367  ? 146.774 165.739 124.063 1.00 278.53 ? 385  ARG A CA  1 
ATOM   2795 C C   . ARG A 1 367  ? 146.095 166.598 123.004 1.00 276.92 ? 385  ARG A C   1 
ATOM   2796 O O   . ARG A 1 367  ? 146.530 167.727 122.753 1.00 273.60 ? 385  ARG A O   1 
ATOM   2797 C CB  . ARG A 1 367  ? 147.957 164.991 123.450 1.00 278.22 ? 385  ARG A CB  1 
ATOM   2798 C CG  . ARG A 1 367  ? 149.030 164.598 124.452 1.00 275.71 ? 385  ARG A CG  1 
ATOM   2799 C CD  . ARG A 1 367  ? 150.298 164.134 123.755 1.00 275.38 ? 385  ARG A CD  1 
ATOM   2800 N NE  . ARG A 1 367  ? 151.014 165.241 123.129 1.00 273.86 ? 385  ARG A NE  1 
ATOM   2801 C CZ  . ARG A 1 367  ? 151.924 165.121 122.169 1.00 272.76 ? 385  ARG A CZ  1 
ATOM   2802 N NH1 . ARG A 1 367  ? 152.285 163.940 121.690 1.00 275.51 ? 385  ARG A NH1 1 
ATOM   2803 N NH2 . ARG A 1 367  ? 152.494 166.218 121.679 1.00 268.71 ? 385  ARG A NH2 1 
ATOM   2804 N N   . ARG A 1 368  ? 145.034 166.088 122.377 1.00 277.59 ? 386  ARG A N   1 
ATOM   2805 C CA  . ARG A 1 368  ? 144.350 166.855 121.342 1.00 274.20 ? 386  ARG A CA  1 
ATOM   2806 C C   . ARG A 1 368  ? 143.587 168.034 121.932 1.00 272.09 ? 386  ARG A C   1 
ATOM   2807 O O   . ARG A 1 368  ? 143.451 169.072 121.274 1.00 269.91 ? 386  ARG A O   1 
ATOM   2808 C CB  . ARG A 1 368  ? 143.405 165.949 120.549 1.00 272.28 ? 386  ARG A CB  1 
ATOM   2809 C CG  . ARG A 1 368  ? 144.046 164.659 120.036 1.00 273.63 ? 386  ARG A CG  1 
ATOM   2810 C CD  . ARG A 1 368  ? 143.069 163.820 119.233 1.00 271.79 ? 386  ARG A CD  1 
ATOM   2811 N NE  . ARG A 1 368  ? 143.032 162.441 119.707 1.00 274.38 ? 386  ARG A NE  1 
ATOM   2812 C CZ  . ARG A 1 368  ? 143.972 161.530 119.482 1.00 274.70 ? 386  ARG A CZ  1 
ATOM   2813 N NH1 . ARG A 1 368  ? 145.064 161.810 118.783 1.00 274.58 ? 386  ARG A NH1 1 
ATOM   2814 N NH2 . ARG A 1 368  ? 143.817 160.305 119.974 1.00 274.05 ? 386  ARG A NH2 1 
ATOM   2815 N N   . ASN A 1 369  ? 143.089 167.899 123.158 1.00 272.08 ? 387  ASN A N   1 
ATOM   2816 C CA  . ASN A 1 369  ? 142.371 168.992 123.797 1.00 269.39 ? 387  ASN A CA  1 
ATOM   2817 C C   . ASN A 1 369  ? 143.343 170.084 124.229 1.00 270.41 ? 387  ASN A C   1 
ATOM   2818 O O   . ASN A 1 369  ? 144.476 169.807 124.631 1.00 270.89 ? 387  ASN A O   1 
ATOM   2819 C CB  . ASN A 1 369  ? 141.586 168.478 125.003 1.00 267.79 ? 387  ASN A CB  1 
ATOM   2820 C CG  . ASN A 1 369  ? 140.724 167.277 124.669 1.00 265.74 ? 387  ASN A CG  1 
ATOM   2821 O OD1 . ASN A 1 369  ? 141.106 166.134 124.922 1.00 269.18 ? 387  ASN A OD1 1 
ATOM   2822 N ND2 . ASN A 1 369  ? 139.554 167.529 124.094 1.00 259.91 ? 387  ASN A ND2 1 
ATOM   2823 N N   . ASN A 1 370  ? 142.887 171.333 124.088 1.00 268.46 ? 388  ASN A N   1 
ATOM   2824 C CA  . ASN A 1 370  ? 143.705 172.528 124.422 1.00 266.58 ? 388  ASN A CA  1 
ATOM   2825 C C   . ASN A 1 370  ? 143.478 172.894 125.890 1.00 263.90 ? 388  ASN A C   1 
ATOM   2826 O O   . ASN A 1 370  ? 142.351 172.714 126.388 1.00 262.13 ? 388  ASN A O   1 
ATOM   2827 C CB  . ASN A 1 370  ? 143.392 173.721 123.514 1.00 265.56 ? 388  ASN A CB  1 
ATOM   2828 C CG  . ASN A 1 370  ? 143.893 173.531 122.097 1.00 265.05 ? 388  ASN A CG  1 
ATOM   2829 O OD1 . ASN A 1 370  ? 144.812 172.748 121.877 1.00 265.23 ? 388  ASN A OD1 1 
ATOM   2830 N ND2 . ASN A 1 370  ? 143.321 174.222 121.117 1.00 262.69 ? 388  ASN A ND2 1 
ATOM   2831 N N   . VAL A 1 371  ? 144.528 173.386 126.541 1.00 261.70 ? 389  VAL A N   1 
ATOM   2832 C CA  . VAL A 1 371  ? 144.437 173.960 127.878 1.00 257.55 ? 389  VAL A CA  1 
ATOM   2833 C C   . VAL A 1 371  ? 144.114 175.441 127.750 1.00 253.41 ? 389  VAL A C   1 
ATOM   2834 O O   . VAL A 1 371  ? 144.803 176.177 127.033 1.00 251.87 ? 389  VAL A O   1 
ATOM   2835 C CB  . VAL A 1 371  ? 145.748 173.747 128.654 1.00 255.04 ? 389  VAL A CB  1 
ATOM   2836 C CG1 . VAL A 1 371  ? 145.579 174.151 130.120 1.00 249.59 ? 389  VAL A CG1 1 
ATOM   2837 C CG2 . VAL A 1 371  ? 146.221 172.299 128.529 1.00 255.55 ? 389  VAL A CG2 1 
ATOM   2838 N N   . VAL A 1 372  ? 143.066 175.882 128.439 1.00 251.89 ? 390  VAL A N   1 
ATOM   2839 C CA  . VAL A 1 372  ? 142.683 177.289 128.455 1.00 247.51 ? 390  VAL A CA  1 
ATOM   2840 C C   . VAL A 1 372  ? 143.422 177.958 129.604 1.00 243.58 ? 390  VAL A C   1 
ATOM   2841 O O   . VAL A 1 372  ? 143.212 177.607 130.770 1.00 242.56 ? 390  VAL A O   1 
ATOM   2842 C CB  . VAL A 1 372  ? 141.162 177.450 128.606 1.00 246.49 ? 390  VAL A CB  1 
ATOM   2843 C CG1 . VAL A 1 372  ? 140.797 178.913 128.845 1.00 242.60 ? 390  VAL A CG1 1 
ATOM   2844 C CG2 . VAL A 1 372  ? 140.443 176.904 127.378 1.00 245.77 ? 390  VAL A CG2 1 
ATOM   2845 N N   . ILE A 1 373  ? 144.279 178.926 129.282 1.00 239.94 ? 391  ILE A N   1 
ATOM   2846 C CA  . ILE A 1 373  ? 145.077 179.645 130.268 1.00 236.88 ? 391  ILE A CA  1 
ATOM   2847 C C   . ILE A 1 373  ? 144.627 181.098 130.244 1.00 235.35 ? 391  ILE A C   1 
ATOM   2848 O O   . ILE A 1 373  ? 144.662 181.748 129.191 1.00 236.39 ? 391  ILE A O   1 
ATOM   2849 C CB  . ILE A 1 373  ? 146.584 179.506 129.990 1.00 236.90 ? 391  ILE A CB  1 
ATOM   2850 C CG1 . ILE A 1 373  ? 147.040 178.100 130.403 1.00 236.59 ? 391  ILE A CG1 1 
ATOM   2851 C CG2 . ILE A 1 373  ? 147.387 180.608 130.723 1.00 238.98 ? 391  ILE A CG2 1 
ATOM   2852 C CD1 . ILE A 1 373  ? 148.459 177.735 130.002 1.00 238.67 ? 391  ILE A CD1 1 
ATOM   2853 N N   . THR A 1 374  ? 144.207 181.597 131.404 1.00 231.12 ? 392  THR A N   1 
ATOM   2854 C CA  . THR A 1 374  ? 143.716 182.957 131.572 1.00 227.48 ? 392  THR A CA  1 
ATOM   2855 C C   . THR A 1 374  ? 144.673 183.718 132.478 1.00 227.13 ? 392  THR A C   1 
ATOM   2856 O O   . THR A 1 374  ? 145.067 183.215 133.535 1.00 228.22 ? 392  THR A O   1 
ATOM   2857 C CB  . THR A 1 374  ? 142.304 182.965 132.165 1.00 225.87 ? 392  THR A CB  1 
ATOM   2858 O OG1 . THR A 1 374  ? 141.467 182.071 131.422 1.00 227.07 ? 392  THR A OG1 1 
ATOM   2859 C CG2 . THR A 1 374  ? 141.706 184.367 132.121 1.00 222.98 ? 392  THR A CG2 1 
ATOM   2860 N N   . VAL A 1 375  ? 145.043 184.925 132.056 1.00 225.69 ? 393  VAL A N   1 
ATOM   2861 C CA  . VAL A 1 375  ? 145.961 185.790 132.788 1.00 226.23 ? 393  VAL A CA  1 
ATOM   2862 C C   . VAL A 1 375  ? 145.245 187.100 133.077 1.00 225.92 ? 393  VAL A C   1 
ATOM   2863 O O   . VAL A 1 375  ? 144.655 187.703 132.173 1.00 226.12 ? 393  VAL A O   1 
ATOM   2864 C CB  . VAL A 1 375  ? 147.273 186.028 132.011 1.00 226.45 ? 393  VAL A CB  1 
ATOM   2865 C CG1 . VAL A 1 375  ? 147.010 186.383 130.547 1.00 225.98 ? 393  VAL A CG1 1 
ATOM   2866 C CG2 . VAL A 1 375  ? 148.102 187.122 132.677 1.00 226.78 ? 393  VAL A CG2 1 
ATOM   2867 N N   . THR A 1 376  ? 145.296 187.529 134.339 1.00 226.71 ? 394  THR A N   1 
ATOM   2868 C CA  . THR A 1 376  ? 144.679 188.769 134.799 1.00 228.60 ? 394  THR A CA  1 
ATOM   2869 C C   . THR A 1 376  ? 145.766 189.632 135.423 1.00 228.42 ? 394  THR A C   1 
ATOM   2870 O O   . THR A 1 376  ? 146.308 189.286 136.478 1.00 227.07 ? 394  THR A O   1 
ATOM   2871 C CB  . THR A 1 376  ? 143.562 188.487 135.805 1.00 228.26 ? 394  THR A CB  1 
ATOM   2872 O OG1 . THR A 1 376  ? 142.538 187.703 135.181 1.00 229.48 ? 394  THR A OG1 1 
ATOM   2873 C CG2 . THR A 1 376  ? 142.962 189.789 136.326 1.00 226.52 ? 394  THR A CG2 1 
ATOM   2874 N N   . GLN A 1 377  ? 146.082 190.747 134.767 1.00 228.79 ? 395  GLN A N   1 
ATOM   2875 C CA  . GLN A 1 377  ? 147.050 191.725 135.256 1.00 228.31 ? 395  GLN A CA  1 
ATOM   2876 C C   . GLN A 1 377  ? 146.267 192.940 135.733 1.00 230.06 ? 395  GLN A C   1 
ATOM   2877 O O   . GLN A 1 377  ? 145.656 193.641 134.920 1.00 231.97 ? 395  GLN A O   1 
ATOM   2878 C CB  . GLN A 1 377  ? 148.043 192.103 134.159 1.00 229.93 ? 395  GLN A CB  1 
ATOM   2879 C CG  . GLN A 1 377  ? 148.914 190.952 133.683 1.00 230.97 ? 395  GLN A CG  1 
ATOM   2880 C CD  . GLN A 1 377  ? 149.785 191.330 132.500 1.00 230.96 ? 395  GLN A CD  1 
ATOM   2881 O OE1 . GLN A 1 377  ? 150.400 192.396 132.482 1.00 231.17 ? 395  GLN A OE1 1 
ATOM   2882 N NE2 . GLN A 1 377  ? 149.843 190.454 131.503 1.00 228.53 ? 395  GLN A NE2 1 
ATOM   2883 N N   . ARG A 1 378  ? 146.291 193.190 137.043 1.00 231.01 ? 396  ARG A N   1 
ATOM   2884 C CA  . ARG A 1 378  ? 145.485 194.233 137.667 1.00 232.15 ? 396  ARG A CA  1 
ATOM   2885 C C   . ARG A 1 378  ? 146.384 195.215 138.404 1.00 231.50 ? 396  ARG A C   1 
ATOM   2886 O O   . ARG A 1 378  ? 147.307 194.815 139.119 1.00 232.68 ? 396  ARG A O   1 
ATOM   2887 C CB  . ARG A 1 378  ? 144.443 193.648 138.642 1.00 231.11 ? 396  ARG A CB  1 
ATOM   2888 C CG  . ARG A 1 378  ? 144.974 192.669 139.703 1.00 235.48 ? 396  ARG A CG  1 
ATOM   2889 C CD  . ARG A 1 378  ? 143.937 191.616 140.086 1.00 239.16 ? 396  ARG A CD  1 
ATOM   2890 N NE  . ARG A 1 378  ? 144.527 190.517 140.843 1.00 243.68 ? 396  ARG A NE  1 
ATOM   2891 C CZ  . ARG A 1 378  ? 143.854 189.483 141.333 1.00 245.65 ? 396  ARG A CZ  1 
ATOM   2892 N NH1 . ARG A 1 378  ? 142.544 189.360 141.171 1.00 245.58 ? 396  ARG A NH1 1 
ATOM   2893 N NH2 . ARG A 1 378  ? 144.512 188.543 142.006 1.00 244.18 ? 396  ARG A NH2 1 
ATOM   2894 N N   . ASN A 1 379  ? 146.099 196.505 138.220 1.00 228.47 ? 397  ASN A N   1 
ATOM   2895 C CA  . ASN A 1 379  ? 146.864 197.580 138.853 1.00 227.56 ? 397  ASN A CA  1 
ATOM   2896 C C   . ASN A 1 379  ? 146.254 197.903 140.217 1.00 225.72 ? 397  ASN A C   1 
ATOM   2897 O O   . ASN A 1 379  ? 145.652 198.956 140.440 1.00 222.24 ? 397  ASN A O   1 
ATOM   2898 C CB  . ASN A 1 379  ? 146.897 198.805 137.948 1.00 225.72 ? 397  ASN A CB  1 
ATOM   2899 C CG  . ASN A 1 379  ? 147.768 199.915 138.501 1.00 225.33 ? 397  ASN A CG  1 
ATOM   2900 O OD1 . ASN A 1 379  ? 148.923 199.691 138.861 1.00 228.14 ? 397  ASN A OD1 1 
ATOM   2901 N ND2 . ASN A 1 379  ? 147.216 201.122 138.573 1.00 217.05 ? 397  ASN A ND2 1 
ATOM   2902 N N   . TYR A 1 380  ? 146.429 196.959 141.139 1.00 225.50 ? 398  TYR A N   1 
ATOM   2903 C CA  . TYR A 1 380  ? 145.925 197.083 142.506 1.00 219.29 ? 398  TYR A CA  1 
ATOM   2904 C C   . TYR A 1 380  ? 147.070 197.348 143.477 1.00 215.39 ? 398  TYR A C   1 
ATOM   2905 O O   . TYR A 1 380  ? 148.082 196.649 143.464 1.00 216.34 ? 398  TYR A O   1 
ATOM   2906 C CB  . TYR A 1 380  ? 145.171 195.818 142.915 1.00 217.07 ? 398  TYR A CB  1 
ATOM   2907 C CG  . TYR A 1 380  ? 144.012 196.078 143.850 1.00 212.99 ? 398  TYR A CG  1 
ATOM   2908 C CD1 . TYR A 1 380  ? 144.227 196.367 145.191 1.00 205.76 ? 398  TYR A CD1 1 
ATOM   2909 C CD2 . TYR A 1 380  ? 142.703 196.039 143.390 1.00 211.38 ? 398  TYR A CD2 1 
ATOM   2910 C CE1 . TYR A 1 380  ? 143.170 196.606 146.049 1.00 203.25 ? 398  TYR A CE1 1 
ATOM   2911 C CE2 . TYR A 1 380  ? 141.640 196.277 144.240 1.00 208.17 ? 398  TYR A CE2 1 
ATOM   2912 C CZ  . TYR A 1 380  ? 141.879 196.560 145.568 1.00 205.30 ? 398  TYR A CZ  1 
ATOM   2913 O OH  . TYR A 1 380  ? 140.823 196.798 146.418 1.00 197.26 ? 398  TYR A OH  1 
ATOM   2914 N N   . LYS A 1 393  ? 144.145 200.487 139.372 1.00 216.70 ? 411  LYS A N   1 
ATOM   2915 C CA  . LYS A 1 393  ? 142.801 200.851 138.940 1.00 217.39 ? 411  LYS A CA  1 
ATOM   2916 C C   . LYS A 1 393  ? 142.325 199.947 137.810 1.00 226.89 ? 411  LYS A C   1 
ATOM   2917 O O   . LYS A 1 393  ? 141.326 199.241 137.945 1.00 229.50 ? 411  LYS A O   1 
ATOM   2918 C CB  . LYS A 1 393  ? 142.759 202.311 138.484 1.00 203.67 ? 411  LYS A CB  1 
ATOM   2919 C CG  . LYS A 1 393  ? 142.998 203.319 139.593 1.00 189.39 ? 411  LYS A CG  1 
ATOM   2920 C CD  . LYS A 1 393  ? 143.042 204.735 139.042 1.00 179.01 ? 411  LYS A CD  1 
ATOM   2921 C CE  . LYS A 1 393  ? 143.283 205.755 140.141 1.00 170.74 ? 411  LYS A CE  1 
ATOM   2922 N NZ  . LYS A 1 393  ? 143.321 207.145 139.607 1.00 167.72 ? 411  LYS A NZ  1 
ATOM   2923 N N   . MET A 1 394  ? 143.051 199.976 136.697 1.00 231.45 ? 412  MET A N   1 
ATOM   2924 C CA  . MET A 1 394  ? 142.672 199.220 135.512 1.00 233.96 ? 412  MET A CA  1 
ATOM   2925 C C   . MET A 1 394  ? 143.200 197.793 135.601 1.00 237.19 ? 412  MET A C   1 
ATOM   2926 O O   . MET A 1 394  ? 144.186 197.508 136.285 1.00 233.12 ? 412  MET A O   1 
ATOM   2927 C CB  . MET A 1 394  ? 143.192 199.879 134.227 1.00 226.93 ? 412  MET A CB  1 
ATOM   2928 C CG  . MET A 1 394  ? 144.661 200.312 134.240 1.00 224.19 ? 412  MET A CG  1 
ATOM   2929 S SD  . MET A 1 394  ? 145.014 201.673 135.373 1.00 218.69 ? 412  MET A SD  1 
ATOM   2930 C CE  . MET A 1 394  ? 144.101 203.015 134.614 1.00 201.16 ? 412  MET A CE  1 
ATOM   2931 N N   . GLU A 1 395  ? 142.516 196.891 134.897 1.00 241.92 ? 413  GLU A N   1 
ATOM   2932 C CA  . GLU A 1 395  ? 142.904 195.491 134.817 1.00 240.14 ? 413  GLU A CA  1 
ATOM   2933 C C   . GLU A 1 395  ? 142.721 195.000 133.389 1.00 239.90 ? 413  GLU A C   1 
ATOM   2934 O O   . GLU A 1 395  ? 141.883 195.513 132.642 1.00 239.40 ? 413  GLU A O   1 
ATOM   2935 C CB  . GLU A 1 395  ? 142.093 194.619 135.790 1.00 237.90 ? 413  GLU A CB  1 
ATOM   2936 C CG  . GLU A 1 395  ? 140.572 194.777 135.688 1.00 239.31 ? 413  GLU A CG  1 
ATOM   2937 C CD  . GLU A 1 395  ? 140.019 195.866 136.593 1.00 235.88 ? 413  GLU A CD  1 
ATOM   2938 O OE1 . GLU A 1 395  ? 140.803 196.703 137.086 1.00 239.22 ? 413  GLU A OE1 1 
ATOM   2939 O OE2 . GLU A 1 395  ? 138.789 195.884 136.810 1.00 226.34 ? 413  GLU A OE2 1 
ATOM   2940 N N   . ALA A 1 396  ? 143.519 193.999 133.022 1.00 236.53 ? 414  ALA A N   1 
ATOM   2941 C CA  . ALA A 1 396  ? 143.482 193.382 131.703 1.00 230.74 ? 414  ALA A CA  1 
ATOM   2942 C C   . ALA A 1 396  ? 143.413 191.873 131.869 1.00 226.74 ? 414  ALA A C   1 
ATOM   2943 O O   . ALA A 1 396  ? 144.237 191.286 132.578 1.00 227.17 ? 414  ALA A O   1 
ATOM   2944 C CB  . ALA A 1 396  ? 144.712 193.767 130.876 1.00 230.75 ? 414  ALA A CB  1 
ATOM   2945 N N   . VAL A 1 397  ? 142.438 191.255 131.205 1.00 223.77 ? 415  VAL A N   1 
ATOM   2946 C CA  . VAL A 1 397  ? 142.222 189.812 131.244 1.00 224.48 ? 415  VAL A CA  1 
ATOM   2947 C C   . VAL A 1 397  ? 142.395 189.283 129.828 1.00 224.14 ? 415  VAL A C   1 
ATOM   2948 O O   . VAL A 1 397  ? 141.766 189.791 128.891 1.00 220.90 ? 415  VAL A O   1 
ATOM   2949 C CB  . VAL A 1 397  ? 140.833 189.455 131.798 1.00 222.01 ? 415  VAL A CB  1 
ATOM   2950 C CG1 . VAL A 1 397  ? 140.584 187.954 131.685 1.00 222.87 ? 415  VAL A CG1 1 
ATOM   2951 C CG2 . VAL A 1 397  ? 140.700 189.921 133.244 1.00 218.80 ? 415  VAL A CG2 1 
ATOM   2952 N N   . GLN A 1 398  ? 143.356 188.353 129.761 1.00 225.65 ? 416  GLN A N   1 
ATOM   2953 C CA  . GLN A 1 398  ? 143.692 187.788 128.464 1.00 225.76 ? 416  GLN A CA  1 
ATOM   2954 C C   . GLN A 1 398  ? 143.614 186.270 128.557 1.00 226.56 ? 416  GLN A C   1 
ATOM   2955 O O   . GLN A 1 398  ? 143.828 185.686 129.623 1.00 225.97 ? 416  GLN A O   1 
ATOM   2956 C CB  . GLN A 1 398  ? 145.095 188.239 128.006 1.00 227.27 ? 416  GLN A CB  1 
ATOM   2957 C CG  . GLN A 1 398  ? 145.469 187.827 126.588 1.00 228.72 ? 416  GLN A CG  1 
ATOM   2958 C CD  . GLN A 1 398  ? 146.951 187.932 126.306 1.00 233.87 ? 416  GLN A CD  1 
ATOM   2959 O OE1 . GLN A 1 398  ? 147.737 188.320 127.170 1.00 237.71 ? 416  GLN A OE1 1 
ATOM   2960 N NE2 . GLN A 1 398  ? 147.342 187.589 125.086 1.00 235.58 ? 416  GLN A NE2 1 
ATOM   2961 N N   . LYS A 1 399  ? 143.272 185.635 127.441 1.00 227.83 ? 417  LYS A N   1 
ATOM   2962 C CA  . LYS A 1 399  ? 143.160 184.190 127.366 1.00 231.23 ? 417  LYS A CA  1 
ATOM   2963 C C   . LYS A 1 399  ? 144.118 183.727 126.275 1.00 234.76 ? 417  LYS A C   1 
ATOM   2964 O O   . LYS A 1 399  ? 144.287 184.397 125.251 1.00 234.50 ? 417  LYS A O   1 
ATOM   2965 C CB  . LYS A 1 399  ? 141.663 183.799 127.119 1.00 228.43 ? 417  LYS A CB  1 
ATOM   2966 C CG  . LYS A 1 399  ? 141.173 182.319 126.917 1.00 232.78 ? 417  LYS A CG  1 
ATOM   2967 C CD  . LYS A 1 399  ? 141.842 181.396 125.889 1.00 237.77 ? 417  LYS A CD  1 
ATOM   2968 C CE  . LYS A 1 399  ? 141.231 180.026 125.920 1.00 241.35 ? 417  LYS A CE  1 
ATOM   2969 N NZ  . LYS A 1 399  ? 141.953 179.098 125.018 1.00 243.12 ? 417  LYS A NZ  1 
ATOM   2970 N N   . ILE A 1 400  ? 144.754 182.582 126.504 1.00 237.15 ? 418  ILE A N   1 
ATOM   2971 C CA  . ILE A 1 400  ? 145.639 181.972 125.516 1.00 240.07 ? 418  ILE A CA  1 
ATOM   2972 C C   . ILE A 1 400  ? 145.365 180.467 125.481 1.00 242.91 ? 418  ILE A C   1 
ATOM   2973 O O   . ILE A 1 400  ? 145.212 179.820 126.527 1.00 241.49 ? 418  ILE A O   1 
ATOM   2974 C CB  . ILE A 1 400  ? 147.122 182.299 125.813 1.00 239.84 ? 418  ILE A CB  1 
ATOM   2975 C CG1 . ILE A 1 400  ? 148.073 181.644 124.804 1.00 239.65 ? 418  ILE A CG1 1 
ATOM   2976 C CG2 . ILE A 1 400  ? 147.494 181.964 127.256 1.00 238.54 ? 418  ILE A CG2 1 
ATOM   2977 C CD1 . ILE A 1 400  ? 148.013 182.252 123.430 1.00 236.96 ? 418  ILE A CD1 1 
ATOM   2978 N N   . ASN A 1 401  ? 145.214 179.932 124.268 1.00 246.77 ? 419  ASN A N   1 
ATOM   2979 C CA  . ASN A 1 401  ? 145.100 178.494 124.080 1.00 250.17 ? 419  ASN A CA  1 
ATOM   2980 C C   . ASN A 1 401  ? 146.512 177.908 124.182 1.00 249.11 ? 419  ASN A C   1 
ATOM   2981 O O   . ASN A 1 401  ? 147.477 178.484 123.674 1.00 244.31 ? 419  ASN A O   1 
ATOM   2982 C CB  . ASN A 1 401  ? 144.445 178.186 122.712 1.00 251.78 ? 419  ASN A CB  1 
ATOM   2983 C CG  . ASN A 1 401  ? 144.066 176.705 122.537 1.00 257.50 ? 419  ASN A CG  1 
ATOM   2984 O OD1 . ASN A 1 401  ? 144.762 175.833 123.055 1.00 260.98 ? 419  ASN A OD1 1 
ATOM   2985 N ND2 . ASN A 1 401  ? 142.987 176.401 121.774 1.00 256.81 ? 419  ASN A ND2 1 
ATOM   2986 N N   . TYR A 1 402  ? 146.632 176.747 124.832 1.00 251.57 ? 420  TYR A N   1 
ATOM   2987 C CA  . TYR A 1 402  ? 147.934 176.108 125.020 1.00 249.24 ? 420  TYR A CA  1 
ATOM   2988 C C   . TYR A 1 402  ? 147.819 174.600 124.866 1.00 254.07 ? 420  TYR A C   1 
ATOM   2989 O O   . TYR A 1 402  ? 146.805 174.014 125.247 1.00 256.72 ? 420  TYR A O   1 
ATOM   2990 C CB  . TYR A 1 402  ? 148.535 176.434 126.394 1.00 245.73 ? 420  TYR A CB  1 
ATOM   2991 C CG  . TYR A 1 402  ? 149.614 177.496 126.379 1.00 240.58 ? 420  TYR A CG  1 
ATOM   2992 C CD1 . TYR A 1 402  ? 150.892 177.200 125.917 1.00 239.10 ? 420  TYR A CD1 1 
ATOM   2993 C CD2 . TYR A 1 402  ? 149.357 178.786 126.815 1.00 239.02 ? 420  TYR A CD2 1 
ATOM   2994 C CE1 . TYR A 1 402  ? 151.891 178.154 125.901 1.00 236.79 ? 420  TYR A CE1 1 
ATOM   2995 C CE2 . TYR A 1 402  ? 150.352 179.749 126.803 1.00 238.63 ? 420  TYR A CE2 1 
ATOM   2996 C CZ  . TYR A 1 402  ? 151.616 179.429 126.343 1.00 237.79 ? 420  TYR A CZ  1 
ATOM   2997 O OH  . TYR A 1 402  ? 152.603 180.392 126.329 1.00 236.70 ? 420  TYR A OH  1 
ATOM   2998 N N   . THR A 1 403  ? 148.856 173.980 124.306 1.00 254.47 ? 421  THR A N   1 
ATOM   2999 C CA  . THR A 1 403  ? 148.869 172.541 124.091 1.00 257.48 ? 421  THR A CA  1 
ATOM   3000 C C   . THR A 1 403  ? 149.563 171.817 125.249 1.00 259.12 ? 421  THR A C   1 
ATOM   3001 O O   . THR A 1 403  ? 150.062 172.428 126.198 1.00 258.85 ? 421  THR A O   1 
ATOM   3002 C CB  . THR A 1 403  ? 149.551 172.206 122.766 1.00 256.90 ? 421  THR A CB  1 
ATOM   3003 O OG1 . THR A 1 403  ? 149.341 170.824 122.454 1.00 257.47 ? 421  THR A OG1 1 
ATOM   3004 C CG2 . THR A 1 403  ? 151.045 172.488 122.845 1.00 255.83 ? 421  THR A CG2 1 
ATOM   3005 N N   . VAL A 1 404  ? 149.577 170.337 125.246 1.00 261.45 ? 422  VAL A N   1 
ATOM   3006 C CA  . VAL A 1 404  ? 150.194 169.555 126.316 1.00 262.10 ? 422  VAL A CA  1 
ATOM   3007 C C   . VAL A 1 404  ? 150.922 168.374 125.673 1.00 263.59 ? 422  VAL A C   1 
ATOM   3008 O O   . VAL A 1 404  ? 150.328 167.691 124.826 1.00 265.61 ? 422  VAL A O   1 
ATOM   3009 C CB  . VAL A 1 404  ? 149.150 169.089 127.350 1.00 262.59 ? 422  VAL A CB  1 
ATOM   3010 C CG1 . VAL A 1 404  ? 147.988 168.332 126.695 1.00 266.72 ? 422  VAL A CG1 1 
ATOM   3011 C CG2 . VAL A 1 404  ? 149.803 168.242 128.435 1.00 262.28 ? 422  VAL A CG2 1 
ATOM   3012 N N   . PRO A 1 405  ? 152.204 168.085 126.019 1.00 262.82 ? 423  PRO A N   1 
ATOM   3013 C CA  . PRO A 1 405  ? 152.884 166.947 125.384 1.00 265.34 ? 423  PRO A CA  1 
ATOM   3014 C C   . PRO A 1 405  ? 152.585 165.633 126.089 1.00 271.25 ? 423  PRO A C   1 
ATOM   3015 O O   . PRO A 1 405  ? 151.781 165.594 127.026 1.00 271.48 ? 423  PRO A O   1 
ATOM   3016 C CB  . PRO A 1 405  ? 154.365 167.330 125.488 1.00 261.28 ? 423  PRO A CB  1 
ATOM   3017 C CG  . PRO A 1 405  ? 154.451 168.131 126.726 1.00 260.52 ? 423  PRO A CG  1 
ATOM   3018 C CD  . PRO A 1 405  ? 153.113 168.792 126.940 1.00 259.20 ? 423  PRO A CD  1 
ATOM   3019 N N   . GLN A 1 406  ? 153.223 164.549 125.639 1.00 273.70 ? 424  GLN A N   1 
ATOM   3020 C CA  . GLN A 1 406  ? 153.035 163.253 126.282 1.00 277.00 ? 424  GLN A CA  1 
ATOM   3021 C C   . GLN A 1 406  ? 153.517 163.277 127.728 1.00 278.90 ? 424  GLN A C   1 
ATOM   3022 O O   . GLN A 1 406  ? 152.858 162.725 128.617 1.00 281.38 ? 424  GLN A O   1 
ATOM   3023 C CB  . GLN A 1 406  ? 153.768 162.172 125.488 1.00 275.70 ? 424  GLN A CB  1 
ATOM   3024 C CG  . GLN A 1 406  ? 153.307 160.747 125.768 1.00 275.56 ? 424  GLN A CG  1 
ATOM   3025 C CD  . GLN A 1 406  ? 151.915 160.459 125.236 1.00 274.73 ? 424  GLN A CD  1 
ATOM   3026 O OE1 . GLN A 1 406  ? 151.471 161.064 124.260 1.00 275.40 ? 424  GLN A OE1 1 
ATOM   3027 N NE2 . GLN A 1 406  ? 151.222 159.524 125.875 1.00 273.28 ? 424  GLN A NE2 1 
ATOM   3028 N N   . SER A 1 407  ? 154.665 163.910 127.982 1.00 276.78 ? 425  SER A N   1 
ATOM   3029 C CA  . SER A 1 407  ? 155.164 164.008 129.350 1.00 276.40 ? 425  SER A CA  1 
ATOM   3030 C C   . SER A 1 407  ? 154.297 164.926 130.203 1.00 276.36 ? 425  SER A C   1 
ATOM   3031 O O   . SER A 1 407  ? 154.220 164.742 131.423 1.00 276.60 ? 425  SER A O   1 
ATOM   3032 C CB  . SER A 1 407  ? 156.608 164.505 129.344 1.00 273.42 ? 425  SER A CB  1 
ATOM   3033 O OG  . SER A 1 407  ? 156.678 165.858 128.928 1.00 272.33 ? 425  SER A OG  1 
ATOM   3034 N N   . GLY A 1 408  ? 153.645 165.914 129.587 1.00 274.02 ? 426  GLY A N   1 
ATOM   3035 C CA  . GLY A 1 408  ? 152.800 166.854 130.291 1.00 270.12 ? 426  GLY A CA  1 
ATOM   3036 C C   . GLY A 1 408  ? 153.483 168.137 130.716 1.00 266.06 ? 426  GLY A C   1 
ATOM   3037 O O   . GLY A 1 408  ? 152.788 169.118 131.013 1.00 261.51 ? 426  GLY A O   1 
ATOM   3038 N N   . THR A 1 409  ? 154.812 168.170 130.746 1.00 267.40 ? 427  THR A N   1 
ATOM   3039 C CA  . THR A 1 409  ? 155.559 169.365 131.116 1.00 262.56 ? 427  THR A CA  1 
ATOM   3040 C C   . THR A 1 409  ? 155.716 170.256 129.891 1.00 259.19 ? 427  THR A C   1 
ATOM   3041 O O   . THR A 1 409  ? 156.178 169.796 128.841 1.00 261.22 ? 427  THR A O   1 
ATOM   3042 C CB  . THR A 1 409  ? 156.931 168.993 131.680 1.00 261.98 ? 427  THR A CB  1 
ATOM   3043 O OG1 . THR A 1 409  ? 156.810 167.842 132.526 1.00 265.91 ? 427  THR A OG1 1 
ATOM   3044 C CG2 . THR A 1 409  ? 157.534 170.156 132.463 1.00 253.13 ? 427  THR A CG2 1 
ATOM   3045 N N   . PHE A 1 410  ? 155.328 171.524 130.020 1.00 254.35 ? 428  PHE A N   1 
ATOM   3046 C CA  . PHE A 1 410  ? 155.504 172.469 128.924 1.00 251.35 ? 428  PHE A CA  1 
ATOM   3047 C C   . PHE A 1 410  ? 155.592 173.886 129.462 1.00 246.16 ? 428  PHE A C   1 
ATOM   3048 O O   . PHE A 1 410  ? 154.935 174.228 130.447 1.00 244.81 ? 428  PHE A O   1 
ATOM   3049 C CB  . PHE A 1 410  ? 154.366 172.367 127.903 1.00 250.93 ? 428  PHE A CB  1 
ATOM   3050 C CG  . PHE A 1 410  ? 153.034 172.825 128.423 1.00 251.72 ? 428  PHE A CG  1 
ATOM   3051 C CD1 . PHE A 1 410  ? 152.283 172.014 129.258 1.00 253.36 ? 428  PHE A CD1 1 
ATOM   3052 C CD2 . PHE A 1 410  ? 152.527 174.065 128.070 1.00 248.53 ? 428  PHE A CD2 1 
ATOM   3053 C CE1 . PHE A 1 410  ? 151.057 172.432 129.734 1.00 252.28 ? 428  PHE A CE1 1 
ATOM   3054 C CE2 . PHE A 1 410  ? 151.301 174.488 128.544 1.00 247.36 ? 428  PHE A CE2 1 
ATOM   3055 C CZ  . PHE A 1 410  ? 150.565 173.670 129.377 1.00 249.35 ? 428  PHE A CZ  1 
ATOM   3056 N N   . LYS A 1 411  ? 156.398 174.708 128.796 1.00 241.94 ? 429  LYS A N   1 
ATOM   3057 C CA  . LYS A 1 411  ? 156.617 176.084 129.214 1.00 235.77 ? 429  LYS A CA  1 
ATOM   3058 C C   . LYS A 1 411  ? 155.569 177.004 128.605 1.00 233.99 ? 429  LYS A C   1 
ATOM   3059 O O   . LYS A 1 411  ? 155.158 176.827 127.455 1.00 234.04 ? 429  LYS A O   1 
ATOM   3060 C CB  . LYS A 1 411  ? 158.016 176.553 128.813 1.00 230.72 ? 429  LYS A CB  1 
ATOM   3061 C CG  . LYS A 1 411  ? 159.086 176.225 129.840 1.00 229.32 ? 429  LYS A CG  1 
ATOM   3062 C CD  . LYS A 1 411  ? 160.472 176.589 129.339 1.00 226.17 ? 429  LYS A CD  1 
ATOM   3063 C CE  . LYS A 1 411  ? 161.544 176.193 130.341 1.00 220.72 ? 429  LYS A CE  1 
ATOM   3064 N NZ  . LYS A 1 411  ? 162.909 176.239 129.749 1.00 214.55 ? 429  LYS A NZ  1 
ATOM   3065 N N   . ILE A 1 412  ? 155.140 177.984 129.397 1.00 229.83 ? 430  ILE A N   1 
ATOM   3066 C CA  . ILE A 1 412  ? 154.243 179.047 128.964 1.00 228.42 ? 430  ILE A CA  1 
ATOM   3067 C C   . ILE A 1 412  ? 154.969 180.370 129.151 1.00 225.10 ? 430  ILE A C   1 
ATOM   3068 O O   . ILE A 1 412  ? 155.617 180.590 130.181 1.00 223.40 ? 430  ILE A O   1 
ATOM   3069 C CB  . ILE A 1 412  ? 152.903 179.031 129.736 1.00 229.32 ? 430  ILE A CB  1 
ATOM   3070 C CG1 . ILE A 1 412  ? 153.095 179.333 131.230 1.00 226.28 ? 430  ILE A CG1 1 
ATOM   3071 C CG2 . ILE A 1 412  ? 152.214 177.687 129.568 1.00 233.21 ? 430  ILE A CG2 1 
ATOM   3072 C CD1 . ILE A 1 412  ? 152.788 180.772 131.628 1.00 223.93 ? 430  ILE A CD1 1 
ATOM   3073 N N   . GLU A 1 413  ? 154.878 181.237 128.144 1.00 225.79 ? 431  GLU A N   1 
ATOM   3074 C CA  . GLU A 1 413  ? 155.572 182.518 128.136 1.00 225.55 ? 431  GLU A CA  1 
ATOM   3075 C C   . GLU A 1 413  ? 154.605 183.596 127.677 1.00 226.39 ? 431  GLU A C   1 
ATOM   3076 O O   . GLU A 1 413  ? 153.781 183.353 126.790 1.00 230.68 ? 431  GLU A O   1 
ATOM   3077 C CB  . GLU A 1 413  ? 156.801 182.472 127.216 1.00 230.20 ? 431  GLU A CB  1 
ATOM   3078 C CG  . GLU A 1 413  ? 157.512 183.810 127.017 1.00 230.98 ? 431  GLU A CG  1 
ATOM   3079 C CD  . GLU A 1 413  ? 158.831 183.665 126.283 1.00 233.10 ? 431  GLU A CD  1 
ATOM   3080 O OE1 . GLU A 1 413  ? 159.125 182.551 125.799 1.00 238.09 ? 431  GLU A OE1 1 
ATOM   3081 O OE2 . GLU A 1 413  ? 159.573 184.666 126.187 1.00 229.79 ? 431  GLU A OE2 1 
ATOM   3082 N N   . PHE A 1 414  ? 154.701 184.780 128.279 1.00 222.04 ? 432  PHE A N   1 
ATOM   3083 C CA  . PHE A 1 414  ? 153.901 185.910 127.826 1.00 217.49 ? 432  PHE A CA  1 
ATOM   3084 C C   . PHE A 1 414  ? 154.484 187.201 128.384 1.00 212.25 ? 432  PHE A C   1 
ATOM   3085 O O   . PHE A 1 414  ? 155.096 187.179 129.456 1.00 210.80 ? 432  PHE A O   1 
ATOM   3086 C CB  . PHE A 1 414  ? 152.432 185.767 128.255 1.00 215.35 ? 432  PHE A CB  1 
ATOM   3087 C CG  . PHE A 1 414  ? 152.242 185.638 129.740 1.00 217.39 ? 432  PHE A CG  1 
ATOM   3088 C CD1 . PHE A 1 414  ? 152.281 184.396 130.350 1.00 220.89 ? 432  PHE A CD1 1 
ATOM   3089 C CD2 . PHE A 1 414  ? 152.011 186.756 130.525 1.00 217.15 ? 432  PHE A CD2 1 
ATOM   3090 C CE1 . PHE A 1 414  ? 152.103 184.273 131.713 1.00 221.84 ? 432  PHE A CE1 1 
ATOM   3091 C CE2 . PHE A 1 414  ? 151.836 186.639 131.888 1.00 220.11 ? 432  PHE A CE2 1 
ATOM   3092 C CZ  . PHE A 1 414  ? 151.880 185.396 132.483 1.00 221.71 ? 432  PHE A CZ  1 
ATOM   3093 N N   . PRO A 1 415  ? 154.305 188.334 127.702 1.00 209.56 ? 433  PRO A N   1 
ATOM   3094 C CA  . PRO A 1 415  ? 154.784 189.601 128.263 1.00 209.39 ? 433  PRO A CA  1 
ATOM   3095 C C   . PRO A 1 415  ? 153.870 190.109 129.368 1.00 210.35 ? 433  PRO A C   1 
ATOM   3096 O O   . PRO A 1 415  ? 152.695 189.749 129.458 1.00 211.22 ? 433  PRO A O   1 
ATOM   3097 C CB  . PRO A 1 415  ? 154.777 190.549 127.061 1.00 208.15 ? 433  PRO A CB  1 
ATOM   3098 C CG  . PRO A 1 415  ? 153.704 190.024 126.195 1.00 205.85 ? 433  PRO A CG  1 
ATOM   3099 C CD  . PRO A 1 415  ? 153.717 188.533 126.363 1.00 208.84 ? 433  PRO A CD  1 
ATOM   3100 N N   . ILE A 1 416  ? 154.438 190.967 130.215 1.00 211.47 ? 434  ILE A N   1 
ATOM   3101 C CA  . ILE A 1 416  ? 153.715 191.643 131.288 1.00 217.63 ? 434  ILE A CA  1 
ATOM   3102 C C   . ILE A 1 416  ? 153.581 193.107 130.897 1.00 220.44 ? 434  ILE A C   1 
ATOM   3103 O O   . ILE A 1 416  ? 154.563 193.739 130.489 1.00 216.49 ? 434  ILE A O   1 
ATOM   3104 C CB  . ILE A 1 416  ? 154.423 191.515 132.653 1.00 216.20 ? 434  ILE A CB  1 
ATOM   3105 C CG1 . ILE A 1 416  ? 154.858 190.070 132.950 1.00 213.39 ? 434  ILE A CG1 1 
ATOM   3106 C CG2 . ILE A 1 416  ? 153.493 191.995 133.790 1.00 218.56 ? 434  ILE A CG2 1 
ATOM   3107 C CD1 . ILE A 1 416  ? 155.693 189.936 134.218 1.00 212.33 ? 434  ILE A CD1 1 
ATOM   3108 N N   . LEU A 1 417  ? 152.371 193.642 131.021 1.00 224.15 ? 435  LEU A N   1 
ATOM   3109 C CA  . LEU A 1 417  ? 152.175 195.072 130.841 1.00 226.25 ? 435  LEU A CA  1 
ATOM   3110 C C   . LEU A 1 417  ? 152.861 195.837 131.967 1.00 229.17 ? 435  LEU A C   1 
ATOM   3111 O O   . LEU A 1 417  ? 152.899 195.393 133.118 1.00 229.16 ? 435  LEU A O   1 
ATOM   3112 C CB  . LEU A 1 417  ? 150.682 195.411 130.808 1.00 224.19 ? 435  LEU A CB  1 
ATOM   3113 C CG  . LEU A 1 417  ? 149.942 195.386 129.463 1.00 219.08 ? 435  LEU A CG  1 
ATOM   3114 C CD1 . LEU A 1 417  ? 150.550 196.345 128.444 1.00 215.97 ? 435  LEU A CD1 1 
ATOM   3115 C CD2 . LEU A 1 417  ? 149.910 193.969 128.906 1.00 218.31 ? 435  LEU A CD2 1 
ATOM   3116 N N   . GLU A 1 418  ? 153.409 197.003 131.623 1.00 231.72 ? 436  GLU A N   1 
ATOM   3117 C CA  . GLU A 1 418  ? 154.201 197.774 132.574 1.00 232.54 ? 436  GLU A CA  1 
ATOM   3118 C C   . GLU A 1 418  ? 153.383 198.291 133.752 1.00 237.68 ? 436  GLU A C   1 
ATOM   3119 O O   . GLU A 1 418  ? 153.952 198.521 134.824 1.00 237.33 ? 436  GLU A O   1 
ATOM   3120 C CB  . GLU A 1 418  ? 154.900 198.935 131.846 1.00 232.23 ? 436  GLU A CB  1 
ATOM   3121 C CG  . GLU A 1 418  ? 154.068 200.206 131.583 1.00 231.79 ? 436  GLU A CG  1 
ATOM   3122 C CD  . GLU A 1 418  ? 152.892 199.962 130.659 1.00 234.25 ? 436  GLU A CD  1 
ATOM   3123 O OE1 . GLU A 1 418  ? 152.815 198.864 130.069 1.00 233.71 ? 436  GLU A OE1 1 
ATOM   3124 O OE2 . GLU A 1 418  ? 152.045 200.869 130.522 1.00 235.07 ? 436  GLU A OE2 1 
ATOM   3125 N N   . ASP A 1 419  ? 152.074 198.473 133.585 1.00 239.12 ? 437  ASP A N   1 
ATOM   3126 C CA  . ASP A 1 419  ? 151.216 198.972 134.652 1.00 238.83 ? 437  ASP A CA  1 
ATOM   3127 C C   . ASP A 1 419  ? 150.687 197.863 135.557 1.00 239.05 ? 437  ASP A C   1 
ATOM   3128 O O   . ASP A 1 419  ? 149.922 198.152 136.483 1.00 236.83 ? 437  ASP A O   1 
ATOM   3129 C CB  . ASP A 1 419  ? 150.040 199.752 134.060 1.00 237.54 ? 437  ASP A CB  1 
ATOM   3130 C CG  . ASP A 1 419  ? 149.035 198.856 133.366 1.00 238.20 ? 437  ASP A CG  1 
ATOM   3131 O OD1 . ASP A 1 419  ? 149.454 197.847 132.763 1.00 237.91 ? 437  ASP A OD1 1 
ATOM   3132 O OD2 . ASP A 1 419  ? 147.825 199.160 133.425 1.00 233.84 ? 437  ASP A OD2 1 
ATOM   3133 N N   . SER A 1 420  ? 151.071 196.610 135.318 1.00 239.57 ? 438  SER A N   1 
ATOM   3134 C CA  . SER A 1 420  ? 150.594 195.503 136.132 1.00 237.01 ? 438  SER A CA  1 
ATOM   3135 C C   . SER A 1 420  ? 151.188 195.584 137.532 1.00 234.09 ? 438  SER A C   1 
ATOM   3136 O O   . SER A 1 420  ? 152.394 195.799 137.691 1.00 231.42 ? 438  SER A O   1 
ATOM   3137 C CB  . SER A 1 420  ? 150.963 194.170 135.483 1.00 234.94 ? 438  SER A CB  1 
ATOM   3138 O OG  . SER A 1 420  ? 150.781 194.222 134.079 1.00 234.21 ? 438  SER A OG  1 
ATOM   3139 N N   . SER A 1 421  ? 150.331 195.415 138.543 1.00 232.45 ? 439  SER A N   1 
ATOM   3140 C CA  . SER A 1 421  ? 150.742 195.358 139.939 1.00 230.54 ? 439  SER A CA  1 
ATOM   3141 C C   . SER A 1 421  ? 150.495 194.004 140.583 1.00 230.87 ? 439  SER A C   1 
ATOM   3142 O O   . SER A 1 421  ? 151.185 193.664 141.550 1.00 226.55 ? 439  SER A O   1 
ATOM   3143 C CB  . SER A 1 421  ? 150.008 196.433 140.755 1.00 228.05 ? 439  SER A CB  1 
ATOM   3144 O OG  . SER A 1 421  ? 148.673 196.045 141.034 1.00 227.86 ? 439  SER A OG  1 
ATOM   3145 N N   . GLU A 1 422  ? 149.534 193.233 140.079 1.00 234.22 ? 440  GLU A N   1 
ATOM   3146 C CA  . GLU A 1 422  ? 149.245 191.898 140.582 1.00 235.34 ? 440  GLU A CA  1 
ATOM   3147 C C   . GLU A 1 422  ? 148.847 191.016 139.411 1.00 233.11 ? 440  GLU A C   1 
ATOM   3148 O O   . GLU A 1 422  ? 148.044 191.424 138.565 1.00 230.33 ? 440  GLU A O   1 
ATOM   3149 C CB  . GLU A 1 422  ? 148.132 191.931 141.635 1.00 239.23 ? 440  GLU A CB  1 
ATOM   3150 C CG  . GLU A 1 422  ? 147.864 190.595 142.311 1.00 240.83 ? 440  GLU A CG  1 
ATOM   3151 C CD  . GLU A 1 422  ? 146.836 190.704 143.418 1.00 244.93 ? 440  GLU A CD  1 
ATOM   3152 O OE1 . GLU A 1 422  ? 146.274 191.805 143.600 1.00 244.47 ? 440  GLU A OE1 1 
ATOM   3153 O OE2 . GLU A 1 422  ? 146.591 189.692 144.107 1.00 246.65 ? 440  GLU A OE2 1 
ATOM   3154 N N   . LEU A 1 423  ? 149.411 189.812 139.373 1.00 231.53 ? 441  LEU A N   1 
ATOM   3155 C CA  . LEU A 1 423  ? 149.188 188.849 138.305 1.00 230.23 ? 441  LEU A CA  1 
ATOM   3156 C C   . LEU A 1 423  ? 148.449 187.651 138.883 1.00 230.29 ? 441  LEU A C   1 
ATOM   3157 O O   . LEU A 1 423  ? 148.826 187.137 139.939 1.00 230.54 ? 441  LEU A O   1 
ATOM   3158 C CB  . LEU A 1 423  ? 150.531 188.420 137.699 1.00 229.25 ? 441  LEU A CB  1 
ATOM   3159 C CG  . LEU A 1 423  ? 150.750 187.086 136.971 1.00 230.05 ? 441  LEU A CG  1 
ATOM   3160 C CD1 . LEU A 1 423  ? 149.767 186.826 135.835 1.00 229.21 ? 441  LEU A CD1 1 
ATOM   3161 C CD2 . LEU A 1 423  ? 152.179 187.016 136.460 1.00 227.10 ? 441  LEU A CD2 1 
ATOM   3162 N N   . GLN A 1 424  ? 147.378 187.230 138.212 1.00 228.94 ? 442  GLN A N   1 
ATOM   3163 C CA  . GLN A 1 424  ? 146.656 186.014 138.563 1.00 228.41 ? 442  GLN A CA  1 
ATOM   3164 C C   . GLN A 1 424  ? 146.597 185.118 137.337 1.00 225.59 ? 442  GLN A C   1 
ATOM   3165 O O   . GLN A 1 424  ? 146.100 185.532 136.284 1.00 224.89 ? 442  GLN A O   1 
ATOM   3166 C CB  . GLN A 1 424  ? 145.243 186.320 139.066 1.00 230.76 ? 442  GLN A CB  1 
ATOM   3167 C CG  . GLN A 1 424  ? 144.580 185.137 139.755 1.00 233.52 ? 442  GLN A CG  1 
ATOM   3168 C CD  . GLN A 1 424  ? 143.156 185.426 140.187 1.00 236.13 ? 442  GLN A CD  1 
ATOM   3169 O OE1 . GLN A 1 424  ? 142.326 185.848 139.382 1.00 237.23 ? 442  GLN A OE1 1 
ATOM   3170 N NE2 . GLN A 1 424  ? 142.865 185.194 141.462 1.00 233.50 ? 442  GLN A NE2 1 
ATOM   3171 N N   . LEU A 1 425  ? 147.106 183.896 137.479 1.00 223.48 ? 443  LEU A N   1 
ATOM   3172 C CA  . LEU A 1 425  ? 147.141 182.907 136.412 1.00 226.26 ? 443  LEU A CA  1 
ATOM   3173 C C   . LEU A 1 425  ? 146.150 181.805 136.752 1.00 227.72 ? 443  LEU A C   1 
ATOM   3174 O O   . LEU A 1 425  ? 146.086 181.363 137.904 1.00 226.48 ? 443  LEU A O   1 
ATOM   3175 C CB  . LEU A 1 425  ? 148.559 182.343 136.243 1.00 229.91 ? 443  LEU A CB  1 
ATOM   3176 C CG  . LEU A 1 425  ? 148.784 181.014 135.511 1.00 234.94 ? 443  LEU A CG  1 
ATOM   3177 C CD1 . LEU A 1 425  ? 148.365 181.129 134.058 1.00 234.29 ? 443  LEU A CD1 1 
ATOM   3178 C CD2 . LEU A 1 425  ? 150.243 180.609 135.610 1.00 237.24 ? 443  LEU A CD2 1 
ATOM   3179 N N   . LYS A 1 426  ? 145.372 181.383 135.756 1.00 229.50 ? 444  LYS A N   1 
ATOM   3180 C CA  . LYS A 1 426  ? 144.411 180.298 135.889 1.00 230.91 ? 444  LYS A CA  1 
ATOM   3181 C C   . LYS A 1 426  ? 144.583 179.349 134.715 1.00 232.70 ? 444  LYS A C   1 
ATOM   3182 O O   . LYS A 1 426  ? 144.785 179.790 133.581 1.00 231.30 ? 444  LYS A O   1 
ATOM   3183 C CB  . LYS A 1 426  ? 142.972 180.822 135.920 1.00 230.90 ? 444  LYS A CB  1 
ATOM   3184 C CG  . LYS A 1 426  ? 142.618 181.616 137.179 1.00 230.44 ? 444  LYS A CG  1 
ATOM   3185 C CD  . LYS A 1 426  ? 142.844 183.128 137.043 1.00 232.27 ? 444  LYS A CD  1 
ATOM   3186 C CE  . LYS A 1 426  ? 141.839 183.822 136.122 1.00 234.49 ? 444  LYS A CE  1 
ATOM   3187 N NZ  . LYS A 1 426  ? 142.272 185.210 135.802 1.00 233.25 ? 444  LYS A NZ  1 
ATOM   3188 N N   . ALA A 1 427  ? 144.503 178.049 134.993 1.00 236.20 ? 445  ALA A N   1 
ATOM   3189 C CA  . ALA A 1 427  ? 144.608 177.002 133.986 1.00 239.35 ? 445  ALA A CA  1 
ATOM   3190 C C   . ALA A 1 427  ? 143.398 176.090 134.102 1.00 244.11 ? 445  ALA A C   1 
ATOM   3191 O O   . ALA A 1 427  ? 143.032 175.679 135.208 1.00 244.34 ? 445  ALA A O   1 
ATOM   3192 C CB  . ALA A 1 427  ? 145.899 176.196 134.154 1.00 242.06 ? 445  ALA A CB  1 
ATOM   3193 N N   . TYR A 1 428  ? 142.779 175.786 132.961 1.00 245.77 ? 446  TYR A N   1 
ATOM   3194 C CA  . TYR A 1 428  ? 141.609 174.923 132.887 1.00 246.75 ? 446  TYR A CA  1 
ATOM   3195 C C   . TYR A 1 428  ? 141.821 173.888 131.794 1.00 248.60 ? 446  TYR A C   1 
ATOM   3196 O O   . TYR A 1 428  ? 142.309 174.210 130.705 1.00 250.93 ? 446  TYR A O   1 
ATOM   3197 C CB  . TYR A 1 428  ? 140.341 175.736 132.614 1.00 246.80 ? 446  TYR A CB  1 
ATOM   3198 C CG  . TYR A 1 428  ? 140.122 176.850 133.612 1.00 249.68 ? 446  TYR A CG  1 
ATOM   3199 C CD1 . TYR A 1 428  ? 139.889 176.571 134.952 1.00 249.35 ? 446  TYR A CD1 1 
ATOM   3200 C CD2 . TYR A 1 428  ? 140.155 178.180 133.216 1.00 248.42 ? 446  TYR A CD2 1 
ATOM   3201 C CE1 . TYR A 1 428  ? 139.691 177.585 135.869 1.00 248.81 ? 446  TYR A CE1 1 
ATOM   3202 C CE2 . TYR A 1 428  ? 139.957 179.201 134.126 1.00 248.53 ? 446  TYR A CE2 1 
ATOM   3203 C CZ  . TYR A 1 428  ? 139.726 178.897 135.451 1.00 249.34 ? 446  TYR A CZ  1 
ATOM   3204 O OH  . TYR A 1 428  ? 139.529 179.910 136.361 1.00 249.05 ? 446  TYR A OH  1 
ATOM   3205 N N   . PHE A 1 429  ? 141.457 172.642 132.094 1.00 250.29 ? 447  PHE A N   1 
ATOM   3206 C CA  . PHE A 1 429  ? 141.657 171.540 131.154 1.00 254.81 ? 447  PHE A CA  1 
ATOM   3207 C C   . PHE A 1 429  ? 140.621 170.462 131.459 1.00 256.14 ? 447  PHE A C   1 
ATOM   3208 O O   . PHE A 1 429  ? 140.791 169.690 132.407 1.00 257.45 ? 447  PHE A O   1 
ATOM   3209 C CB  . PHE A 1 429  ? 143.073 170.992 131.252 1.00 255.82 ? 447  PHE A CB  1 
ATOM   3210 C CG  . PHE A 1 429  ? 143.310 169.782 130.401 1.00 260.41 ? 447  PHE A CG  1 
ATOM   3211 C CD1 . PHE A 1 429  ? 143.303 169.879 129.020 1.00 262.06 ? 447  PHE A CD1 1 
ATOM   3212 C CD2 . PHE A 1 429  ? 143.536 168.545 130.980 1.00 263.47 ? 447  PHE A CD2 1 
ATOM   3213 C CE1 . PHE A 1 429  ? 143.522 168.768 128.234 1.00 266.81 ? 447  PHE A CE1 1 
ATOM   3214 C CE2 . PHE A 1 429  ? 143.754 167.429 130.198 1.00 268.54 ? 447  PHE A CE2 1 
ATOM   3215 C CZ  . PHE A 1 429  ? 143.747 167.541 128.822 1.00 271.09 ? 447  PHE A CZ  1 
ATOM   3216 N N   . LEU A 1 430  ? 139.567 170.409 130.640 1.00 254.57 ? 448  LEU A N   1 
ATOM   3217 C CA  . LEU A 1 430  ? 138.528 169.382 130.744 1.00 253.05 ? 448  LEU A CA  1 
ATOM   3218 C C   . LEU A 1 430  ? 137.903 169.362 132.138 1.00 250.73 ? 448  LEU A C   1 
ATOM   3219 O O   . LEU A 1 430  ? 137.631 168.301 132.703 1.00 251.07 ? 448  LEU A O   1 
ATOM   3220 C CB  . LEU A 1 430  ? 139.088 168.003 130.381 1.00 257.58 ? 448  LEU A CB  1 
ATOM   3221 C CG  . LEU A 1 430  ? 139.650 167.843 128.964 1.00 258.90 ? 448  LEU A CG  1 
ATOM   3222 C CD1 . LEU A 1 430  ? 140.306 166.479 128.806 1.00 263.32 ? 448  LEU A CD1 1 
ATOM   3223 C CD2 . LEU A 1 430  ? 138.568 168.041 127.910 1.00 254.39 ? 448  LEU A CD2 1 
ATOM   3224 N N   . GLY A 1 431  ? 137.681 170.550 132.698 1.00 248.25 ? 449  GLY A N   1 
ATOM   3225 C CA  . GLY A 1 431  ? 137.126 170.690 134.025 1.00 248.36 ? 449  GLY A CA  1 
ATOM   3226 C C   . GLY A 1 431  ? 138.140 170.684 135.148 1.00 249.07 ? 449  GLY A C   1 
ATOM   3227 O O   . GLY A 1 431  ? 137.780 171.017 136.284 1.00 248.01 ? 449  GLY A O   1 
ATOM   3228 N N   . SER A 1 432  ? 139.393 170.323 134.874 1.00 250.78 ? 450  SER A N   1 
ATOM   3229 C CA  . SER A 1 432  ? 140.447 170.357 135.879 1.00 251.35 ? 450  SER A CA  1 
ATOM   3230 C C   . SER A 1 432  ? 140.985 171.778 135.971 1.00 247.75 ? 450  SER A C   1 
ATOM   3231 O O   . SER A 1 432  ? 141.476 172.321 134.976 1.00 245.61 ? 450  SER A O   1 
ATOM   3232 C CB  . SER A 1 432  ? 141.567 169.379 135.527 1.00 256.06 ? 450  SER A CB  1 
ATOM   3233 O OG  . SER A 1 432  ? 141.091 168.045 135.499 1.00 260.45 ? 450  SER A OG  1 
ATOM   3234 N N   . LYS A 1 433  ? 140.898 172.370 137.162 1.00 247.46 ? 451  LYS A N   1 
ATOM   3235 C CA  . LYS A 1 433  ? 141.210 173.775 137.388 1.00 244.70 ? 451  LYS A CA  1 
ATOM   3236 C C   . LYS A 1 433  ? 142.422 173.915 138.297 1.00 244.06 ? 451  LYS A C   1 
ATOM   3237 O O   . LYS A 1 433  ? 142.612 173.124 139.227 1.00 248.15 ? 451  LYS A O   1 
ATOM   3238 C CB  . LYS A 1 433  ? 140.019 174.510 138.014 1.00 244.07 ? 451  LYS A CB  1 
ATOM   3239 C CG  . LYS A 1 433  ? 138.656 174.030 137.518 1.00 244.58 ? 451  LYS A CG  1 
ATOM   3240 C CD  . LYS A 1 433  ? 137.563 175.088 137.678 1.00 243.39 ? 451  LYS A CD  1 
ATOM   3241 C CE  . LYS A 1 433  ? 136.415 174.852 136.709 1.00 247.74 ? 451  LYS A CE  1 
ATOM   3242 N NZ  . LYS A 1 433  ? 136.777 175.215 135.311 1.00 247.07 ? 451  LYS A NZ  1 
ATOM   3243 N N   . SER A 1 434  ? 143.238 174.928 138.017 1.00 240.89 ? 452  SER A N   1 
ATOM   3244 C CA  . SER A 1 434  ? 144.336 175.310 138.891 1.00 240.00 ? 452  SER A CA  1 
ATOM   3245 C C   . SER A 1 434  ? 144.550 176.809 138.760 1.00 235.89 ? 452  SER A C   1 
ATOM   3246 O O   . SER A 1 434  ? 144.141 177.426 137.775 1.00 233.48 ? 452  SER A O   1 
ATOM   3247 C CB  . SER A 1 434  ? 145.622 174.547 138.557 1.00 245.63 ? 452  SER A CB  1 
ATOM   3248 O OG  . SER A 1 434  ? 146.712 175.030 139.322 1.00 245.03 ? 452  SER A OG  1 
ATOM   3249 N N   . SER A 1 435  ? 145.191 177.395 139.769 1.00 233.26 ? 453  SER A N   1 
ATOM   3250 C CA  . SER A 1 435  ? 145.389 178.836 139.786 1.00 230.74 ? 453  SER A CA  1 
ATOM   3251 C C   . SER A 1 435  ? 146.582 179.182 140.663 1.00 228.84 ? 453  SER A C   1 
ATOM   3252 O O   . SER A 1 435  ? 147.009 178.395 141.512 1.00 226.99 ? 453  SER A O   1 
ATOM   3253 C CB  . SER A 1 435  ? 144.135 179.564 140.284 1.00 229.35 ? 453  SER A CB  1 
ATOM   3254 O OG  . SER A 1 435  ? 143.891 179.277 141.649 1.00 230.01 ? 453  SER A OG  1 
ATOM   3255 N N   . MET A 1 436  ? 147.118 180.380 140.437 1.00 227.60 ? 454  MET A N   1 
ATOM   3256 C CA  . MET A 1 436  ? 148.196 180.919 141.256 1.00 226.15 ? 454  MET A CA  1 
ATOM   3257 C C   . MET A 1 436  ? 148.172 182.432 141.097 1.00 225.31 ? 454  MET A C   1 
ATOM   3258 O O   . MET A 1 436  ? 147.527 182.968 140.191 1.00 223.64 ? 454  MET A O   1 
ATOM   3259 C CB  . MET A 1 436  ? 149.552 180.269 140.878 1.00 225.66 ? 454  MET A CB  1 
ATOM   3260 C CG  . MET A 1 436  ? 150.470 180.913 139.795 1.00 227.02 ? 454  MET A CG  1 
ATOM   3261 S SD  . MET A 1 436  ? 151.225 182.545 140.058 1.00 227.11 ? 454  MET A SD  1 
ATOM   3262 C CE  . MET A 1 436  ? 152.363 182.190 141.396 1.00 221.09 ? 454  MET A CE  1 
ATOM   3263 N N   . ALA A 1 437  ? 148.890 183.119 141.983 1.00 225.35 ? 455  ALA A N   1 
ATOM   3264 C CA  . ALA A 1 437  ? 148.923 184.574 141.961 1.00 226.66 ? 455  ALA A CA  1 
ATOM   3265 C C   . ALA A 1 437  ? 150.265 185.082 142.463 1.00 224.58 ? 455  ALA A C   1 
ATOM   3266 O O   . ALA A 1 437  ? 150.895 184.460 143.321 1.00 221.01 ? 455  ALA A O   1 
ATOM   3267 C CB  . ALA A 1 437  ? 147.795 185.166 142.810 1.00 227.96 ? 455  ALA A CB  1 
ATOM   3268 N N   . VAL A 1 438  ? 150.686 186.217 141.909 1.00 225.61 ? 456  VAL A N   1 
ATOM   3269 C CA  . VAL A 1 438  ? 151.843 186.973 142.374 1.00 225.41 ? 456  VAL A CA  1 
ATOM   3270 C C   . VAL A 1 438  ? 151.352 188.371 142.720 1.00 227.38 ? 456  VAL A C   1 
ATOM   3271 O O   . VAL A 1 438  ? 150.773 189.061 141.869 1.00 228.20 ? 456  VAL A O   1 
ATOM   3272 C CB  . VAL A 1 438  ? 152.963 187.036 141.321 1.00 225.53 ? 456  VAL A CB  1 
ATOM   3273 C CG1 . VAL A 1 438  ? 154.158 187.820 141.861 1.00 223.93 ? 456  VAL A CG1 1 
ATOM   3274 C CG2 . VAL A 1 438  ? 153.396 185.638 140.893 1.00 227.48 ? 456  VAL A CG2 1 
ATOM   3275 N N   . HIS A 1 439  ? 151.580 188.781 143.972 1.00 228.28 ? 457  HIS A N   1 
ATOM   3276 C CA  . HIS A 1 439  ? 151.265 190.119 144.453 1.00 233.02 ? 457  HIS A CA  1 
ATOM   3277 C C   . HIS A 1 439  ? 152.495 190.941 144.800 1.00 230.87 ? 457  HIS A C   1 
ATOM   3278 O O   . HIS A 1 439  ? 152.402 192.172 144.829 1.00 231.97 ? 457  HIS A O   1 
ATOM   3279 C CB  . HIS A 1 439  ? 150.361 190.037 145.695 1.00 237.62 ? 457  HIS A CB  1 
ATOM   3280 C CG  . HIS A 1 439  ? 149.668 191.322 146.034 1.00 240.00 ? 457  HIS A CG  1 
ATOM   3281 N ND1 . HIS A 1 439  ? 149.129 192.160 145.080 1.00 242.05 ? 457  HIS A ND1 1 
ATOM   3282 C CD2 . HIS A 1 439  ? 149.432 191.914 147.229 1.00 234.63 ? 457  HIS A CD2 1 
ATOM   3283 C CE1 . HIS A 1 439  ? 148.589 193.210 145.673 1.00 236.94 ? 457  HIS A CE1 1 
ATOM   3284 N NE2 . HIS A 1 439  ? 148.759 193.085 146.977 1.00 231.74 ? 457  HIS A NE2 1 
ATOM   3285 N N   . SER A 1 440  ? 153.632 190.301 145.061 1.00 229.03 ? 458  SER A N   1 
ATOM   3286 C CA  . SER A 1 440  ? 154.849 191.032 145.379 1.00 227.29 ? 458  SER A CA  1 
ATOM   3287 C C   . SER A 1 440  ? 155.307 191.837 144.170 1.00 224.92 ? 458  SER A C   1 
ATOM   3288 O O   . SER A 1 440  ? 155.308 191.337 143.041 1.00 221.00 ? 458  SER A O   1 
ATOM   3289 C CB  . SER A 1 440  ? 155.947 190.065 145.818 1.00 224.87 ? 458  SER A CB  1 
ATOM   3290 O OG  . SER A 1 440  ? 155.494 189.222 146.864 1.00 221.52 ? 458  SER A OG  1 
ATOM   3291 N N   . LEU A 1 441  ? 155.692 193.088 144.411 1.00 225.90 ? 459  LEU A N   1 
ATOM   3292 C CA  . LEU A 1 441  ? 156.139 193.980 143.353 1.00 222.42 ? 459  LEU A CA  1 
ATOM   3293 C C   . LEU A 1 441  ? 157.175 194.930 143.933 1.00 217.56 ? 459  LEU A C   1 
ATOM   3294 O O   . LEU A 1 441  ? 157.071 195.335 145.094 1.00 216.01 ? 459  LEU A O   1 
ATOM   3295 C CB  . LEU A 1 441  ? 154.960 194.760 142.752 1.00 222.48 ? 459  LEU A CB  1 
ATOM   3296 C CG  . LEU A 1 441  ? 155.231 195.778 141.638 1.00 219.11 ? 459  LEU A CG  1 
ATOM   3297 C CD1 . LEU A 1 441  ? 155.477 195.070 140.315 1.00 216.34 ? 459  LEU A CD1 1 
ATOM   3298 C CD2 . LEU A 1 441  ? 154.069 196.750 141.524 1.00 217.52 ? 459  LEU A CD2 1 
ATOM   3299 N N   . PHE A 1 442  ? 158.170 195.272 143.119 1.00 214.29 ? 460  PHE A N   1 
ATOM   3300 C CA  . PHE A 1 442  ? 159.209 196.227 143.477 1.00 208.11 ? 460  PHE A CA  1 
ATOM   3301 C C   . PHE A 1 442  ? 159.106 197.430 142.551 1.00 204.92 ? 460  PHE A C   1 
ATOM   3302 O O   . PHE A 1 442  ? 158.978 197.273 141.332 1.00 199.87 ? 460  PHE A O   1 
ATOM   3303 C CB  . PHE A 1 442  ? 160.601 195.591 143.375 1.00 206.31 ? 460  PHE A CB  1 
ATOM   3304 C CG  . PHE A 1 442  ? 160.876 194.494 144.395 1.00 204.41 ? 460  PHE A CG  1 
ATOM   3305 C CD1 . PHE A 1 442  ? 160.195 194.421 145.607 1.00 203.02 ? 460  PHE A CD1 1 
ATOM   3306 C CD2 . PHE A 1 442  ? 161.836 193.532 144.127 1.00 202.51 ? 460  PHE A CD2 1 
ATOM   3307 C CE1 . PHE A 1 442  ? 160.464 193.416 146.514 1.00 199.06 ? 460  PHE A CE1 1 
ATOM   3308 C CE2 . PHE A 1 442  ? 162.107 192.524 145.036 1.00 200.58 ? 460  PHE A CE2 1 
ATOM   3309 C CZ  . PHE A 1 442  ? 161.420 192.468 146.229 1.00 199.25 ? 460  PHE A CZ  1 
ATOM   3310 N N   . LYS A 1 443  ? 159.166 198.624 143.134 1.00 202.28 ? 461  LYS A N   1 
ATOM   3311 C CA  . LYS A 1 443  ? 158.867 199.860 142.422 1.00 197.36 ? 461  LYS A CA  1 
ATOM   3312 C C   . LYS A 1 443  ? 160.143 200.469 141.857 1.00 197.78 ? 461  LYS A C   1 
ATOM   3313 O O   . LYS A 1 443  ? 161.101 200.716 142.598 1.00 201.22 ? 461  LYS A O   1 
ATOM   3314 C CB  . LYS A 1 443  ? 158.180 200.866 143.350 1.00 193.53 ? 461  LYS A CB  1 
ATOM   3315 C CG  . LYS A 1 443  ? 156.914 200.360 144.058 1.00 193.41 ? 461  LYS A CG  1 
ATOM   3316 C CD  . LYS A 1 443  ? 156.851 200.829 145.509 1.00 185.20 ? 461  LYS A CD  1 
ATOM   3317 C CE  . LYS A 1 443  ? 155.710 200.168 146.270 1.00 179.25 ? 461  LYS A CE  1 
ATOM   3318 N NZ  . LYS A 1 443  ? 155.914 198.702 146.446 1.00 181.50 ? 461  LYS A NZ  1 
ATOM   3319 N N   . SER A 1 444  ? 160.147 200.707 140.547 1.00 195.71 ? 462  SER A N   1 
ATOM   3320 C CA  . SER A 1 444  ? 161.216 201.419 139.856 1.00 197.30 ? 462  SER A CA  1 
ATOM   3321 C C   . SER A 1 444  ? 160.677 202.776 139.414 1.00 199.97 ? 462  SER A C   1 
ATOM   3322 O O   . SER A 1 444  ? 159.731 202.809 138.608 1.00 198.75 ? 462  SER A O   1 
ATOM   3323 C CB  . SER A 1 444  ? 161.708 200.626 138.646 1.00 194.40 ? 462  SER A CB  1 
ATOM   3324 O OG  . SER A 1 444  ? 162.353 199.432 139.050 1.00 194.93 ? 462  SER A OG  1 
ATOM   3325 N N   . PRO A 1 445  ? 161.191 203.916 139.904 1.00 199.90 ? 463  PRO A N   1 
ATOM   3326 C CA  . PRO A 1 445  ? 160.666 205.200 139.405 1.00 201.69 ? 463  PRO A CA  1 
ATOM   3327 C C   . PRO A 1 445  ? 160.878 205.403 137.916 1.00 203.09 ? 463  PRO A C   1 
ATOM   3328 O O   . PRO A 1 445  ? 160.052 206.062 137.272 1.00 204.22 ? 463  PRO A O   1 
ATOM   3329 C CB  . PRO A 1 445  ? 161.427 206.246 140.233 1.00 196.54 ? 463  PRO A CB  1 
ATOM   3330 C CG  . PRO A 1 445  ? 162.613 205.546 140.757 1.00 194.23 ? 463  PRO A CG  1 
ATOM   3331 C CD  . PRO A 1 445  ? 162.197 204.131 140.961 1.00 194.47 ? 463  PRO A CD  1 
ATOM   3332 N N   . SER A 1 446  ? 161.950 204.856 137.349 1.00 201.41 ? 464  SER A N   1 
ATOM   3333 C CA  . SER A 1 446  ? 162.196 204.917 135.915 1.00 201.13 ? 464  SER A CA  1 
ATOM   3334 C C   . SER A 1 446  ? 161.503 203.801 135.141 1.00 199.60 ? 464  SER A C   1 
ATOM   3335 O O   . SER A 1 446  ? 161.622 203.762 133.912 1.00 199.19 ? 464  SER A O   1 
ATOM   3336 C CB  . SER A 1 446  ? 163.701 204.864 135.638 1.00 198.36 ? 464  SER A CB  1 
ATOM   3337 O OG  . SER A 1 446  ? 164.214 203.565 135.874 1.00 195.74 ? 464  SER A OG  1 
ATOM   3338 N N   . LYS A 1 447  ? 160.788 202.900 135.821 1.00 196.80 ? 465  LYS A N   1 
ATOM   3339 C CA  . LYS A 1 447  ? 160.124 201.763 135.180 1.00 194.24 ? 465  LYS A CA  1 
ATOM   3340 C C   . LYS A 1 447  ? 161.123 200.898 134.413 1.00 192.37 ? 465  LYS A C   1 
ATOM   3341 O O   . LYS A 1 447  ? 160.819 200.375 133.339 1.00 190.29 ? 465  LYS A O   1 
ATOM   3342 C CB  . LYS A 1 447  ? 158.994 202.227 134.258 1.00 196.78 ? 465  LYS A CB  1 
ATOM   3343 C CG  . LYS A 1 447  ? 157.919 203.045 134.951 1.00 199.78 ? 465  LYS A CG  1 
ATOM   3344 C CD  . LYS A 1 447  ? 156.814 203.426 133.980 1.00 202.06 ? 465  LYS A CD  1 
ATOM   3345 C CE  . LYS A 1 447  ? 155.723 204.235 134.661 1.00 201.26 ? 465  LYS A CE  1 
ATOM   3346 N NZ  . LYS A 1 447  ? 154.640 204.616 133.712 1.00 204.27 ? 465  LYS A NZ  1 
ATOM   3347 N N   . THR A 1 448  ? 162.321 200.750 134.973 1.00 191.64 ? 466  THR A N   1 
ATOM   3348 C CA  . THR A 1 448  ? 163.385 199.939 134.395 1.00 187.42 ? 466  THR A CA  1 
ATOM   3349 C C   . THR A 1 448  ? 163.581 198.701 135.256 1.00 182.91 ? 466  THR A C   1 
ATOM   3350 O O   . THR A 1 448  ? 163.761 198.808 136.473 1.00 185.14 ? 466  THR A O   1 
ATOM   3351 C CB  . THR A 1 448  ? 164.692 200.729 134.301 1.00 187.37 ? 466  THR A CB  1 
ATOM   3352 O OG1 . THR A 1 448  ? 164.427 202.040 133.786 1.00 190.42 ? 466  THR A OG1 1 
ATOM   3353 C CG2 . THR A 1 448  ? 165.681 200.021 133.383 1.00 182.66 ? 466  THR A CG2 1 
ATOM   3354 N N   . TYR A 1 449  ? 163.534 197.532 134.620 1.00 176.85 ? 467  TYR A N   1 
ATOM   3355 C CA  . TYR A 1 449  ? 163.693 196.255 135.299 1.00 169.43 ? 467  TYR A CA  1 
ATOM   3356 C C   . TYR A 1 449  ? 164.603 195.369 134.465 1.00 167.80 ? 467  TYR A C   1 
ATOM   3357 O O   . TYR A 1 449  ? 164.685 195.518 133.243 1.00 170.24 ? 467  TYR A O   1 
ATOM   3358 C CB  . TYR A 1 449  ? 162.342 195.561 135.518 1.00 172.09 ? 467  TYR A CB  1 
ATOM   3359 C CG  . TYR A 1 449  ? 161.312 196.440 136.186 1.00 181.57 ? 467  TYR A CG  1 
ATOM   3360 C CD1 . TYR A 1 449  ? 161.227 196.513 137.568 1.00 187.30 ? 467  TYR A CD1 1 
ATOM   3361 C CD2 . TYR A 1 449  ? 160.432 197.205 135.434 1.00 186.01 ? 467  TYR A CD2 1 
ATOM   3362 C CE1 . TYR A 1 449  ? 160.289 197.317 138.183 1.00 192.92 ? 467  TYR A CE1 1 
ATOM   3363 C CE2 . TYR A 1 449  ? 159.491 198.013 136.040 1.00 190.58 ? 467  TYR A CE2 1 
ATOM   3364 C CZ  . TYR A 1 449  ? 159.425 198.066 137.415 1.00 194.23 ? 467  TYR A CZ  1 
ATOM   3365 O OH  . TYR A 1 449  ? 158.490 198.869 138.027 1.00 197.56 ? 467  TYR A OH  1 
ATOM   3366 N N   . ILE A 1 450  ? 165.293 194.451 135.140 1.00 162.25 ? 468  ILE A N   1 
ATOM   3367 C CA  . ILE A 1 450  ? 166.178 193.491 134.493 1.00 155.47 ? 468  ILE A CA  1 
ATOM   3368 C C   . ILE A 1 450  ? 165.893 192.109 135.060 1.00 147.94 ? 468  ILE A C   1 
ATOM   3369 O O   . ILE A 1 450  ? 165.765 191.938 136.277 1.00 148.53 ? 468  ILE A O   1 
ATOM   3370 C CB  . ILE A 1 450  ? 167.671 193.860 134.663 1.00 149.94 ? 468  ILE A CB  1 
ATOM   3371 C CG1 . ILE A 1 450  ? 168.012 194.162 136.128 1.00 148.39 ? 468  ILE A CG1 1 
ATOM   3372 C CG2 . ILE A 1 450  ? 168.022 195.057 133.780 1.00 152.56 ? 468  ILE A CG2 1 
ATOM   3373 C CD1 . ILE A 1 450  ? 169.479 194.458 136.370 1.00 145.40 ? 468  ILE A CD1 1 
ATOM   3374 N N   . GLN A 1 451  ? 165.787 191.128 134.169 1.00 144.96 ? 469  GLN A N   1 
ATOM   3375 C CA  . GLN A 1 451  ? 165.499 189.743 134.514 1.00 146.61 ? 469  GLN A CA  1 
ATOM   3376 C C   . GLN A 1 451  ? 166.746 188.912 134.258 1.00 150.08 ? 469  GLN A C   1 
ATOM   3377 O O   . GLN A 1 451  ? 167.297 188.940 133.152 1.00 150.72 ? 469  GLN A O   1 
ATOM   3378 C CB  . GLN A 1 451  ? 164.320 189.218 133.687 1.00 155.61 ? 469  GLN A CB  1 
ATOM   3379 C CG  . GLN A 1 451  ? 163.810 187.825 134.064 1.00 157.79 ? 469  GLN A CG  1 
ATOM   3380 C CD  . GLN A 1 451  ? 162.712 187.874 135.103 1.00 167.29 ? 469  GLN A CD  1 
ATOM   3381 O OE1 . GLN A 1 451  ? 162.797 188.628 136.069 1.00 169.99 ? 469  GLN A OE1 1 
ATOM   3382 N NE2 . GLN A 1 451  ? 161.670 187.074 134.907 1.00 176.62 ? 469  GLN A NE2 1 
ATOM   3383 N N   . LEU A 1 452  ? 167.180 188.178 135.280 1.00 148.54 ? 470  LEU A N   1 
ATOM   3384 C CA  . LEU A 1 452  ? 168.321 187.276 135.203 1.00 141.17 ? 470  LEU A CA  1 
ATOM   3385 C C   . LEU A 1 452  ? 167.808 185.843 135.176 1.00 140.85 ? 470  LEU A C   1 
ATOM   3386 O O   . LEU A 1 452  ? 166.980 185.463 136.010 1.00 138.80 ? 470  LEU A O   1 
ATOM   3387 C CB  . LEU A 1 452  ? 169.264 187.494 136.389 1.00 134.19 ? 470  LEU A CB  1 
ATOM   3388 C CG  . LEU A 1 452  ? 170.416 186.507 136.600 1.00 134.95 ? 470  LEU A CG  1 
ATOM   3389 C CD1 . LEU A 1 452  ? 171.271 186.382 135.356 1.00 141.95 ? 470  LEU A CD1 1 
ATOM   3390 C CD2 . LEU A 1 452  ? 171.271 186.945 137.773 1.00 128.48 ? 470  LEU A CD2 1 
ATOM   3391 N N   . LYS A 1 453  ? 168.297 185.056 134.217 1.00 142.02 ? 471  LYS A N   1 
ATOM   3392 C CA  . LYS A 1 453  ? 167.824 183.694 134.011 1.00 140.70 ? 471  LYS A CA  1 
ATOM   3393 C C   . LYS A 1 453  ? 168.985 182.795 133.610 1.00 142.96 ? 471  LYS A C   1 
ATOM   3394 O O   . LYS A 1 453  ? 170.066 183.260 133.238 1.00 144.02 ? 471  LYS A O   1 
ATOM   3395 C CB  . LYS A 1 453  ? 166.720 183.644 132.947 1.00 146.83 ? 471  LYS A CB  1 
ATOM   3396 C CG  . LYS A 1 453  ? 165.324 183.886 133.493 1.00 150.50 ? 471  LYS A CG  1 
ATOM   3397 C CD  . LYS A 1 453  ? 164.322 184.102 132.371 1.00 153.94 ? 471  LYS A CD  1 
ATOM   3398 C CE  . LYS A 1 453  ? 162.930 184.370 132.915 1.00 166.44 ? 471  LYS A CE  1 
ATOM   3399 N NZ  . LYS A 1 453  ? 162.058 185.057 131.922 1.00 180.37 ? 471  LYS A NZ  1 
ATOM   3400 N N   . THR A 1 454  ? 168.743 181.488 133.704 1.00 144.09 ? 472  THR A N   1 
ATOM   3401 C CA  . THR A 1 454  ? 169.704 180.465 133.321 1.00 149.71 ? 472  THR A CA  1 
ATOM   3402 C C   . THR A 1 454  ? 169.015 179.414 132.464 1.00 154.20 ? 472  THR A C   1 
ATOM   3403 O O   . THR A 1 454  ? 167.838 179.102 132.663 1.00 152.29 ? 472  THR A O   1 
ATOM   3404 C CB  . THR A 1 454  ? 170.343 179.783 134.547 1.00 151.41 ? 472  THR A CB  1 
ATOM   3405 O OG1 . THR A 1 454  ? 171.293 178.806 134.105 1.00 151.85 ? 472  THR A OG1 1 
ATOM   3406 C CG2 . THR A 1 454  ? 169.291 179.089 135.422 1.00 151.98 ? 472  THR A CG2 1 
ATOM   3407 N N   . ARG A 1 455  ? 169.771 178.868 131.511 1.00 159.47 ? 473  ARG A N   1 
ATOM   3408 C CA  . ARG A 1 455  ? 169.305 177.777 130.665 1.00 166.12 ? 473  ARG A CA  1 
ATOM   3409 C C   . ARG A 1 455  ? 169.761 176.408 131.151 1.00 163.33 ? 473  ARG A C   1 
ATOM   3410 O O   . ARG A 1 455  ? 169.160 175.401 130.763 1.00 164.81 ? 473  ARG A O   1 
ATOM   3411 C CB  . ARG A 1 455  ? 169.793 177.974 129.223 1.00 171.74 ? 473  ARG A CB  1 
ATOM   3412 C CG  . ARG A 1 455  ? 169.524 179.360 128.632 1.00 172.83 ? 473  ARG A CG  1 
ATOM   3413 C CD  . ARG A 1 455  ? 168.047 179.740 128.657 1.00 176.00 ? 473  ARG A CD  1 
ATOM   3414 N NE  . ARG A 1 455  ? 167.212 178.729 128.006 1.00 178.20 ? 473  ARG A NE  1 
ATOM   3415 C CZ  . ARG A 1 455  ? 166.202 178.055 128.551 1.00 183.23 ? 473  ARG A CZ  1 
ATOM   3416 N NH1 . ARG A 1 455  ? 165.819 178.242 129.807 1.00 182.14 ? 473  ARG A NH1 1 
ATOM   3417 N NH2 . ARG A 1 455  ? 165.550 177.163 127.810 1.00 185.54 ? 473  ARG A NH2 1 
ATOM   3418 N N   . ASP A 1 456  ? 170.797 176.346 131.985 1.00 160.39 ? 474  ASP A N   1 
ATOM   3419 C CA  . ASP A 1 456  ? 171.315 175.075 132.470 1.00 161.30 ? 474  ASP A CA  1 
ATOM   3420 C C   . ASP A 1 456  ? 170.401 174.533 133.560 1.00 159.40 ? 474  ASP A C   1 
ATOM   3421 O O   . ASP A 1 456  ? 170.255 175.150 134.621 1.00 156.21 ? 474  ASP A O   1 
ATOM   3422 C CB  . ASP A 1 456  ? 172.736 175.250 133.000 1.00 159.50 ? 474  ASP A CB  1 
ATOM   3423 C CG  . ASP A 1 456  ? 173.748 175.473 131.894 1.00 160.68 ? 474  ASP A CG  1 
ATOM   3424 O OD1 . ASP A 1 456  ? 174.228 174.475 131.317 1.00 164.08 ? 474  ASP A OD1 1 
ATOM   3425 O OD2 . ASP A 1 456  ? 174.059 176.646 131.596 1.00 157.71 ? 474  ASP A OD2 1 
ATOM   3426 N N   . GLU A 1 457  ? 169.786 173.380 133.300 1.00 162.63 ? 475  GLU A N   1 
ATOM   3427 C CA  . GLU A 1 457  ? 168.956 172.728 134.304 1.00 161.54 ? 475  GLU A CA  1 
ATOM   3428 C C   . GLU A 1 457  ? 169.777 172.078 135.411 1.00 158.59 ? 475  GLU A C   1 
ATOM   3429 O O   . GLU A 1 457  ? 169.234 171.817 136.490 1.00 157.41 ? 475  GLU A O   1 
ATOM   3430 C CB  . GLU A 1 457  ? 168.040 171.695 133.630 1.00 161.91 ? 475  GLU A CB  1 
ATOM   3431 C CG  . GLU A 1 457  ? 168.625 170.290 133.411 1.00 166.66 ? 475  GLU A CG  1 
ATOM   3432 C CD  . GLU A 1 457  ? 169.936 170.305 132.646 1.00 169.65 ? 475  GLU A CD  1 
ATOM   3433 O OE1 . GLU A 1 457  ? 170.149 171.243 131.849 1.00 169.43 ? 475  GLU A OE1 1 
ATOM   3434 O OE2 . GLU A 1 457  ? 170.754 169.383 132.846 1.00 169.60 ? 475  GLU A OE2 1 
ATOM   3435 N N   . ASN A 1 458  ? 171.059 171.807 135.168 1.00 155.36 ? 476  ASN A N   1 
ATOM   3436 C CA  . ASN A 1 458  ? 171.944 171.200 136.156 1.00 151.69 ? 476  ASN A CA  1 
ATOM   3437 C C   . ASN A 1 458  ? 173.286 171.909 136.091 1.00 148.49 ? 476  ASN A C   1 
ATOM   3438 O O   . ASN A 1 458  ? 173.947 171.888 135.049 1.00 153.71 ? 476  ASN A O   1 
ATOM   3439 C CB  . ASN A 1 458  ? 172.117 169.701 135.899 1.00 156.09 ? 476  ASN A CB  1 
ATOM   3440 C CG  . ASN A 1 458  ? 172.774 168.984 137.060 1.00 155.84 ? 476  ASN A CG  1 
ATOM   3441 O OD1 . ASN A 1 458  ? 173.162 169.605 138.049 1.00 154.45 ? 476  ASN A OD1 1 
ATOM   3442 N ND2 . ASN A 1 458  ? 172.904 167.668 136.945 1.00 157.87 ? 476  ASN A ND2 1 
ATOM   3443 N N   . ILE A 1 459  ? 173.683 172.524 137.202 1.00 136.98 ? 477  ILE A N   1 
ATOM   3444 C CA  . ILE A 1 459  ? 174.918 173.294 137.301 1.00 130.86 ? 477  ILE A CA  1 
ATOM   3445 C C   . ILE A 1 459  ? 175.859 172.525 138.216 1.00 126.14 ? 477  ILE A C   1 
ATOM   3446 O O   . ILE A 1 459  ? 175.494 172.188 139.349 1.00 129.57 ? 477  ILE A O   1 
ATOM   3447 C CB  . ILE A 1 459  ? 174.673 174.719 137.830 1.00 131.37 ? 477  ILE A CB  1 
ATOM   3448 C CG1 . ILE A 1 459  ? 173.434 175.359 137.178 1.00 137.48 ? 477  ILE A CG1 1 
ATOM   3449 C CG2 . ILE A 1 459  ? 175.900 175.596 137.570 1.00 126.95 ? 477  ILE A CG2 1 
ATOM   3450 C CD1 . ILE A 1 459  ? 173.138 176.768 137.656 1.00 134.53 ? 477  ILE A CD1 1 
ATOM   3451 N N   . LYS A 1 460  ? 177.062 172.250 137.724 1.00 124.95 ? 478  LYS A N   1 
ATOM   3452 C CA  . LYS A 1 460  ? 178.096 171.535 138.457 1.00 127.32 ? 478  LYS A CA  1 
ATOM   3453 C C   . LYS A 1 460  ? 179.251 172.474 138.778 1.00 125.20 ? 478  LYS A C   1 
ATOM   3454 O O   . LYS A 1 460  ? 179.327 173.601 138.282 1.00 128.13 ? 478  LYS A O   1 
ATOM   3455 C CB  . LYS A 1 460  ? 178.599 170.334 137.650 1.00 131.01 ? 478  LYS A CB  1 
ATOM   3456 C CG  . LYS A 1 460  ? 177.501 169.369 137.236 1.00 138.60 ? 478  LYS A CG  1 
ATOM   3457 C CD  . LYS A 1 460  ? 178.060 168.039 136.732 1.00 137.69 ? 478  LYS A CD  1 
ATOM   3458 C CE  . LYS A 1 460  ? 178.952 168.189 135.501 1.00 133.09 ? 478  LYS A CE  1 
ATOM   3459 N NZ  . LYS A 1 460  ? 178.311 168.965 134.402 1.00 134.22 ? 478  LYS A NZ  1 
ATOM   3460 N N   . VAL A 1 461  ? 180.157 171.990 139.620 1.00 124.51 ? 479  VAL A N   1 
ATOM   3461 C CA  . VAL A 1 461  ? 181.351 172.738 139.994 1.00 125.20 ? 479  VAL A CA  1 
ATOM   3462 C C   . VAL A 1 461  ? 182.405 172.513 138.919 1.00 133.00 ? 479  VAL A C   1 
ATOM   3463 O O   . VAL A 1 461  ? 182.724 171.368 138.579 1.00 135.93 ? 479  VAL A O   1 
ATOM   3464 C CB  . VAL A 1 461  ? 181.865 172.313 141.378 1.00 122.15 ? 479  VAL A CB  1 
ATOM   3465 C CG1 . VAL A 1 461  ? 183.283 172.823 141.619 1.00 125.61 ? 479  VAL A CG1 1 
ATOM   3466 C CG2 . VAL A 1 461  ? 180.934 172.821 142.463 1.00 122.70 ? 479  VAL A CG2 1 
ATOM   3467 N N   . GLY A 1 462  ? 182.939 173.607 138.379 1.00 133.35 ? 480  GLY A N   1 
ATOM   3468 C CA  . GLY A 1 462  ? 183.964 173.557 137.364 1.00 137.24 ? 480  GLY A CA  1 
ATOM   3469 C C   . GLY A 1 462  ? 183.450 173.550 135.942 1.00 141.51 ? 480  GLY A C   1 
ATOM   3470 O O   . GLY A 1 462  ? 184.186 173.948 135.032 1.00 144.74 ? 480  GLY A O   1 
ATOM   3471 N N   . SER A 1 463  ? 182.212 173.119 135.724 1.00 138.37 ? 481  SER A N   1 
ATOM   3472 C CA  . SER A 1 463  ? 181.622 173.148 134.392 1.00 138.58 ? 481  SER A CA  1 
ATOM   3473 C C   . SER A 1 463  ? 181.015 174.527 134.143 1.00 132.33 ? 481  SER A C   1 
ATOM   3474 O O   . SER A 1 463  ? 180.140 174.945 134.908 1.00 129.73 ? 481  SER A O   1 
ATOM   3475 C CB  . SER A 1 463  ? 180.549 172.078 134.263 1.00 137.64 ? 481  SER A CB  1 
ATOM   3476 O OG  . SER A 1 463  ? 181.046 170.813 134.660 1.00 139.25 ? 481  SER A OG  1 
ATOM   3477 N N   . PRO A 1 464  ? 181.440 175.270 133.113 1.00 131.63 ? 482  PRO A N   1 
ATOM   3478 C CA  . PRO A 1 464  ? 180.859 176.602 132.910 1.00 129.90 ? 482  PRO A CA  1 
ATOM   3479 C C   . PRO A 1 464  ? 179.391 176.518 132.526 1.00 130.31 ? 482  PRO A C   1 
ATOM   3480 O O   . PRO A 1 464  ? 178.975 175.624 131.785 1.00 134.76 ? 482  PRO A O   1 
ATOM   3481 C CB  . PRO A 1 464  ? 181.703 177.195 131.777 1.00 128.40 ? 482  PRO A CB  1 
ATOM   3482 C CG  . PRO A 1 464  ? 182.199 176.031 131.035 1.00 129.95 ? 482  PRO A CG  1 
ATOM   3483 C CD  . PRO A 1 464  ? 182.418 174.956 132.052 1.00 135.24 ? 482  PRO A CD  1 
ATOM   3484 N N   . PHE A 1 465  ? 178.607 177.464 133.045 1.00 131.51 ? 483  PHE A N   1 
ATOM   3485 C CA  . PHE A 1 465  ? 177.181 177.559 132.766 1.00 135.26 ? 483  PHE A CA  1 
ATOM   3486 C C   . PHE A 1 465  ? 176.842 178.980 132.346 1.00 136.17 ? 483  PHE A C   1 
ATOM   3487 O O   . PHE A 1 465  ? 177.409 179.948 132.860 1.00 134.59 ? 483  PHE A O   1 
ATOM   3488 C CB  . PHE A 1 465  ? 176.338 177.151 133.984 1.00 135.46 ? 483  PHE A CB  1 
ATOM   3489 C CG  . PHE A 1 465  ? 176.225 178.219 135.034 1.00 132.70 ? 483  PHE A CG  1 
ATOM   3490 C CD1 . PHE A 1 465  ? 177.294 178.510 135.859 1.00 127.96 ? 483  PHE A CD1 1 
ATOM   3491 C CD2 . PHE A 1 465  ? 175.049 178.929 135.197 1.00 134.88 ? 483  PHE A CD2 1 
ATOM   3492 C CE1 . PHE A 1 465  ? 177.194 179.487 136.828 1.00 120.40 ? 483  PHE A CE1 1 
ATOM   3493 C CE2 . PHE A 1 465  ? 174.944 179.908 136.164 1.00 125.66 ? 483  PHE A CE2 1 
ATOM   3494 C CZ  . PHE A 1 465  ? 176.018 180.187 136.979 1.00 115.65 ? 483  PHE A CZ  1 
ATOM   3495 N N   . GLU A 1 466  ? 175.903 179.090 131.410 1.00 138.74 ? 484  GLU A N   1 
ATOM   3496 C CA  . GLU A 1 466  ? 175.552 180.361 130.794 1.00 142.74 ? 484  GLU A CA  1 
ATOM   3497 C C   . GLU A 1 466  ? 174.540 181.116 131.643 1.00 142.84 ? 484  GLU A C   1 
ATOM   3498 O O   . GLU A 1 466  ? 173.901 180.552 132.535 1.00 145.31 ? 484  GLU A O   1 
ATOM   3499 C CB  . GLU A 1 466  ? 174.979 180.138 129.393 1.00 152.89 ? 484  GLU A CB  1 
ATOM   3500 C CG  . GLU A 1 466  ? 175.415 181.166 128.355 1.00 158.33 ? 484  GLU A CG  1 
ATOM   3501 C CD  . GLU A 1 466  ? 175.150 180.703 126.936 1.00 175.05 ? 484  GLU A CD  1 
ATOM   3502 O OE1 . GLU A 1 466  ? 173.993 180.814 126.480 1.00 183.32 ? 484  GLU A OE1 1 
ATOM   3503 O OE2 . GLU A 1 466  ? 176.099 180.227 126.278 1.00 178.40 ? 484  GLU A OE2 1 
ATOM   3504 N N   . LEU A 1 467  ? 174.401 182.408 131.351 1.00 143.14 ? 485  LEU A N   1 
ATOM   3505 C CA  . LEU A 1 467  ? 173.487 183.279 132.067 1.00 139.94 ? 485  LEU A CA  1 
ATOM   3506 C C   . LEU A 1 467  ? 172.992 184.377 131.140 1.00 144.13 ? 485  LEU A C   1 
ATOM   3507 O O   . LEU A 1 467  ? 173.778 184.991 130.395 1.00 146.37 ? 485  LEU A O   1 
ATOM   3508 C CB  . LEU A 1 467  ? 174.149 183.904 133.303 1.00 138.00 ? 485  LEU A CB  1 
ATOM   3509 C CG  . LEU A 1 467  ? 174.246 183.029 134.555 1.00 138.15 ? 485  LEU A CG  1 
ATOM   3510 C CD1 . LEU A 1 467  ? 175.096 183.722 135.603 1.00 134.60 ? 485  LEU A CD1 1 
ATOM   3511 C CD2 . LEU A 1 467  ? 172.868 182.707 135.115 1.00 138.83 ? 485  LEU A CD2 1 
ATOM   3512 N N   . VAL A 1 468  ? 171.684 184.629 131.251 1.00 145.58 ? 486  VAL A N   1 
ATOM   3513 C CA  . VAL A 1 468  ? 170.920 185.544 130.413 1.00 146.41 ? 486  VAL A CA  1 
ATOM   3514 C C   . VAL A 1 468  ? 170.511 186.731 131.268 1.00 144.19 ? 486  VAL A C   1 
ATOM   3515 O O   . VAL A 1 468  ? 170.038 186.554 132.397 1.00 140.26 ? 486  VAL A O   1 
ATOM   3516 C CB  . VAL A 1 468  ? 169.666 184.857 129.837 1.00 147.71 ? 486  VAL A CB  1 
ATOM   3517 C CG1 . VAL A 1 468  ? 169.000 185.698 128.738 1.00 148.59 ? 486  VAL A CG1 1 
ATOM   3518 C CG2 . VAL A 1 468  ? 169.993 183.461 129.323 1.00 151.87 ? 486  VAL A CG2 1 
ATOM   3519 N N   . VAL A 1 469  ? 170.680 187.932 130.724 1.00 146.05 ? 487  VAL A N   1 
ATOM   3520 C CA  . VAL A 1 469  ? 170.089 189.147 131.267 1.00 147.20 ? 487  VAL A CA  1 
ATOM   3521 C C   . VAL A 1 469  ? 169.213 189.764 130.185 1.00 150.83 ? 487  VAL A C   1 
ATOM   3522 O O   . VAL A 1 469  ? 169.625 189.877 129.025 1.00 152.22 ? 487  VAL A O   1 
ATOM   3523 C CB  . VAL A 1 469  ? 171.159 190.142 131.768 1.00 146.19 ? 487  VAL A CB  1 
ATOM   3524 C CG1 . VAL A 1 469  ? 172.137 189.440 132.691 1.00 142.58 ? 487  VAL A CG1 1 
ATOM   3525 C CG2 . VAL A 1 469  ? 171.905 190.787 130.614 1.00 150.21 ? 487  VAL A CG2 1 
ATOM   3526 N N   . SER A 1 470  ? 167.986 190.116 130.564 1.00 150.88 ? 488  SER A N   1 
ATOM   3527 C CA  . SER A 1 470  ? 167.015 190.729 129.668 1.00 154.75 ? 488  SER A CA  1 
ATOM   3528 C C   . SER A 1 470  ? 166.504 192.012 130.298 1.00 159.02 ? 488  SER A C   1 
ATOM   3529 O O   . SER A 1 470  ? 166.314 192.084 131.512 1.00 158.51 ? 488  SER A O   1 
ATOM   3530 C CB  . SER A 1 470  ? 165.837 189.790 129.379 1.00 157.97 ? 488  SER A CB  1 
ATOM   3531 O OG  . SER A 1 470  ? 166.275 188.452 129.227 1.00 161.89 ? 488  SER A OG  1 
ATOM   3532 N N   . GLY A 1 471  ? 166.279 193.021 129.467 1.00 165.82 ? 489  GLY A N   1 
ATOM   3533 C CA  . GLY A 1 471  ? 165.866 194.323 129.961 1.00 173.78 ? 489  GLY A CA  1 
ATOM   3534 C C   . GLY A 1 471  ? 165.022 195.063 128.952 1.00 174.75 ? 489  GLY A C   1 
ATOM   3535 O O   . GLY A 1 471  ? 165.170 194.889 127.738 1.00 173.80 ? 489  GLY A O   1 
ATOM   3536 N N   . ASN A 1 472  ? 164.123 195.902 129.468 1.00 174.09 ? 490  ASN A N   1 
ATOM   3537 C CA  . ASN A 1 472  ? 163.283 196.735 128.616 1.00 179.03 ? 490  ASN A CA  1 
ATOM   3538 C C   . ASN A 1 472  ? 164.025 197.934 128.038 1.00 184.17 ? 490  ASN A C   1 
ATOM   3539 O O   . ASN A 1 472  ? 163.520 198.551 127.094 1.00 188.61 ? 490  ASN A O   1 
ATOM   3540 C CB  . ASN A 1 472  ? 162.058 197.228 129.393 1.00 183.20 ? 490  ASN A CB  1 
ATOM   3541 C CG  . ASN A 1 472  ? 162.428 198.023 130.632 1.00 185.78 ? 490  ASN A CG  1 
ATOM   3542 O OD1 . ASN A 1 472  ? 163.544 197.918 131.138 1.00 183.21 ? 490  ASN A OD1 1 
ATOM   3543 N ND2 . ASN A 1 472  ? 161.490 198.821 131.127 1.00 187.75 ? 490  ASN A ND2 1 
ATOM   3544 N N   . LYS A 1 473  ? 165.194 198.279 128.575 1.00 184.83 ? 491  LYS A N   1 
ATOM   3545 C CA  . LYS A 1 473  ? 166.008 199.398 128.112 1.00 186.68 ? 491  LYS A CA  1 
ATOM   3546 C C   . LYS A 1 473  ? 167.402 198.900 127.741 1.00 186.59 ? 491  LYS A C   1 
ATOM   3547 O O   . LYS A 1 473  ? 167.789 197.770 128.045 1.00 184.72 ? 491  LYS A O   1 
ATOM   3548 C CB  . LYS A 1 473  ? 166.105 200.496 129.178 1.00 185.09 ? 491  LYS A CB  1 
ATOM   3549 C CG  . LYS A 1 473  ? 164.793 200.894 129.857 1.00 184.53 ? 491  LYS A CG  1 
ATOM   3550 C CD  . LYS A 1 473  ? 163.805 201.544 128.892 1.00 185.02 ? 491  LYS A CD  1 
ATOM   3551 C CE  . LYS A 1 473  ? 162.401 201.627 129.483 1.00 185.76 ? 491  LYS A CE  1 
ATOM   3552 N NZ  . LYS A 1 473  ? 162.390 201.830 130.960 1.00 185.48 ? 491  LYS A NZ  1 
ATOM   3553 N N   . ARG A 1 474  ? 168.155 199.768 127.071 1.00 187.60 ? 492  ARG A N   1 
ATOM   3554 C CA  . ARG A 1 474  ? 169.540 199.467 126.736 1.00 185.26 ? 492  ARG A CA  1 
ATOM   3555 C C   . ARG A 1 474  ? 170.351 199.373 128.025 1.00 186.66 ? 492  ARG A C   1 
ATOM   3556 O O   . ARG A 1 474  ? 170.208 200.209 128.923 1.00 186.87 ? 492  ARG A O   1 
ATOM   3557 C CB  . ARG A 1 474  ? 170.088 200.548 125.794 1.00 185.88 ? 492  ARG A CB  1 
ATOM   3558 C CG  . ARG A 1 474  ? 171.626 200.554 125.507 1.00 186.46 ? 492  ARG A CG  1 
ATOM   3559 C CD  . ARG A 1 474  ? 172.313 201.937 125.583 1.00 188.74 ? 492  ARG A CD  1 
ATOM   3560 N NE  . ARG A 1 474  ? 171.842 202.801 126.663 1.00 193.51 ? 492  ARG A NE  1 
ATOM   3561 C CZ  . ARG A 1 474  ? 172.151 202.658 127.946 1.00 195.42 ? 492  ARG A CZ  1 
ATOM   3562 N NH1 . ARG A 1 474  ? 172.925 201.672 128.373 1.00 192.98 ? 492  ARG A NH1 1 
ATOM   3563 N NH2 . ARG A 1 474  ? 171.663 203.525 128.829 1.00 197.57 ? 492  ARG A NH2 1 
ATOM   3564 N N   . LEU A 1 475  ? 171.207 198.358 128.106 1.00 184.44 ? 493  LEU A N   1 
ATOM   3565 C CA  . LEU A 1 475  ? 171.943 198.026 129.317 1.00 180.41 ? 493  LEU A CA  1 
ATOM   3566 C C   . LEU A 1 475  ? 173.382 198.519 129.235 1.00 179.23 ? 493  LEU A C   1 
ATOM   3567 O O   . LEU A 1 475  ? 174.002 198.514 128.168 1.00 182.51 ? 493  LEU A O   1 
ATOM   3568 C CB  . LEU A 1 475  ? 171.935 196.513 129.557 1.00 174.40 ? 493  LEU A CB  1 
ATOM   3569 C CG  . LEU A 1 475  ? 170.586 195.799 129.439 1.00 171.09 ? 493  LEU A CG  1 
ATOM   3570 C CD1 . LEU A 1 475  ? 170.764 194.300 129.607 1.00 162.96 ? 493  LEU A CD1 1 
ATOM   3571 C CD2 . LEU A 1 475  ? 169.599 196.342 130.458 1.00 173.89 ? 493  LEU A CD2 1 
ATOM   3572 N N   . LYS A 1 476  ? 173.909 198.943 130.382 1.00 174.24 ? 494  LYS A N   1 
ATOM   3573 C CA  . LYS A 1 476  ? 175.299 199.351 130.505 1.00 172.35 ? 494  LYS A CA  1 
ATOM   3574 C C   . LYS A 1 476  ? 176.160 198.121 130.791 1.00 172.45 ? 494  LYS A C   1 
ATOM   3575 O O   . LYS A 1 476  ? 175.688 196.981 130.747 1.00 173.93 ? 494  LYS A O   1 
ATOM   3576 C CB  . LYS A 1 476  ? 175.448 200.402 131.605 1.00 172.19 ? 494  LYS A CB  1 
ATOM   3577 C CG  . LYS A 1 476  ? 174.582 201.633 131.425 1.00 176.74 ? 494  LYS A CG  1 
ATOM   3578 C CD  . LYS A 1 476  ? 174.887 202.675 132.487 1.00 182.43 ? 494  LYS A CD  1 
ATOM   3579 C CE  . LYS A 1 476  ? 173.965 203.876 132.371 1.00 191.62 ? 494  LYS A CE  1 
ATOM   3580 N NZ  . LYS A 1 476  ? 174.198 204.867 133.458 1.00 194.38 ? 494  LYS A NZ  1 
ATOM   3581 N N   . GLU A 1 477  ? 177.438 198.339 131.088 1.00 168.96 ? 495  GLU A N   1 
ATOM   3582 C CA  . GLU A 1 477  ? 178.313 197.255 131.522 1.00 162.64 ? 495  GLU A CA  1 
ATOM   3583 C C   . GLU A 1 477  ? 177.844 196.761 132.883 1.00 156.41 ? 495  GLU A C   1 
ATOM   3584 O O   . GLU A 1 477  ? 178.022 197.445 133.896 1.00 154.93 ? 495  GLU A O   1 
ATOM   3585 C CB  . GLU A 1 477  ? 179.761 197.735 131.581 1.00 165.92 ? 495  GLU A CB  1 
ATOM   3586 C CG  . GLU A 1 477  ? 180.759 196.662 131.992 1.00 166.04 ? 495  GLU A CG  1 
ATOM   3587 C CD  . GLU A 1 477  ? 182.197 197.103 131.808 1.00 173.32 ? 495  GLU A CD  1 
ATOM   3588 O OE1 . GLU A 1 477  ? 182.519 198.252 132.176 1.00 180.82 ? 495  GLU A OE1 1 
ATOM   3589 O OE2 . GLU A 1 477  ? 183.006 196.302 131.295 1.00 169.70 ? 495  GLU A OE2 1 
ATOM   3590 N N   . LEU A 1 478  ? 177.242 195.578 132.911 1.00 150.40 ? 496  LEU A N   1 
ATOM   3591 C CA  . LEU A 1 478  ? 176.703 195.041 134.150 1.00 147.94 ? 496  LEU A CA  1 
ATOM   3592 C C   . LEU A 1 478  ? 177.831 194.688 135.109 1.00 146.40 ? 496  LEU A C   1 
ATOM   3593 O O   . LEU A 1 478  ? 178.950 194.378 134.694 1.00 147.14 ? 496  LEU A O   1 
ATOM   3594 C CB  . LEU A 1 478  ? 175.855 193.797 133.881 1.00 144.45 ? 496  LEU A CB  1 
ATOM   3595 C CG  . LEU A 1 478  ? 174.346 194.013 133.769 1.00 151.74 ? 496  LEU A CG  1 
ATOM   3596 C CD1 . LEU A 1 478  ? 174.020 195.153 132.815 1.00 163.10 ? 496  LEU A CD1 1 
ATOM   3597 C CD2 . LEU A 1 478  ? 173.671 192.731 133.321 1.00 149.82 ? 496  LEU A CD2 1 
ATOM   3598 N N   . SER A 1 479  ? 177.526 194.746 136.404 1.00 140.87 ? 497  SER A N   1 
ATOM   3599 C CA  . SER A 1 479  ? 178.421 194.286 137.457 1.00 135.66 ? 497  SER A CA  1 
ATOM   3600 C C   . SER A 1 479  ? 177.732 193.139 138.175 1.00 129.62 ? 497  SER A C   1 
ATOM   3601 O O   . SER A 1 479  ? 176.621 193.308 138.689 1.00 130.91 ? 497  SER A O   1 
ATOM   3602 C CB  . SER A 1 479  ? 178.755 195.418 138.429 1.00 140.31 ? 497  SER A CB  1 
ATOM   3603 O OG  . SER A 1 479  ? 179.192 196.570 137.731 1.00 142.30 ? 497  SER A OG  1 
ATOM   3604 N N   . TYR A 1 480  ? 178.383 191.979 138.196 1.00 121.92 ? 498  TYR A N   1 
ATOM   3605 C CA  . TYR A 1 480  ? 177.843 190.774 138.802 1.00 114.27 ? 498  TYR A CA  1 
ATOM   3606 C C   . TYR A 1 480  ? 178.677 190.397 140.016 1.00 111.67 ? 498  TYR A C   1 
ATOM   3607 O O   . TYR A 1 480  ? 179.881 190.668 140.077 1.00 118.10 ? 498  TYR A O   1 
ATOM   3608 C CB  . TYR A 1 480  ? 177.817 189.610 137.807 1.00 118.23 ? 498  TYR A CB  1 
ATOM   3609 C CG  . TYR A 1 480  ? 179.089 188.796 137.759 1.00 116.21 ? 498  TYR A CG  1 
ATOM   3610 C CD1 . TYR A 1 480  ? 180.202 189.253 137.070 1.00 120.71 ? 498  TYR A CD1 1 
ATOM   3611 C CD2 . TYR A 1 480  ? 179.174 187.563 138.392 1.00 116.92 ? 498  TYR A CD2 1 
ATOM   3612 C CE1 . TYR A 1 480  ? 181.361 188.510 137.017 1.00 122.47 ? 498  TYR A CE1 1 
ATOM   3613 C CE2 . TYR A 1 480  ? 180.332 186.816 138.347 1.00 123.43 ? 498  TYR A CE2 1 
ATOM   3614 C CZ  . TYR A 1 480  ? 181.422 187.295 137.658 1.00 122.42 ? 498  TYR A CZ  1 
ATOM   3615 O OH  . TYR A 1 480  ? 182.580 186.554 137.608 1.00 121.28 ? 498  TYR A OH  1 
ATOM   3616 N N   . MET A 1 481  ? 178.014 189.780 140.990 1.00 108.54 ? 499  MET A N   1 
ATOM   3617 C CA  . MET A 1 481  ? 178.665 189.319 142.205 1.00 110.85 ? 499  MET A CA  1 
ATOM   3618 C C   . MET A 1 481  ? 177.968 188.056 142.679 1.00 107.93 ? 499  MET A C   1 
ATOM   3619 O O   . MET A 1 481  ? 176.736 187.976 142.672 1.00 113.97 ? 499  MET A O   1 
ATOM   3620 C CB  . MET A 1 481  ? 178.640 190.400 143.295 1.00 112.32 ? 499  MET A CB  1 
ATOM   3621 C CG  . MET A 1 481  ? 177.252 190.963 143.603 1.00 119.49 ? 499  MET A CG  1 
ATOM   3622 S SD  . MET A 1 481  ? 177.129 192.248 144.879 1.00 145.16 ? 499  MET A SD  1 
ATOM   3623 C CE  . MET A 1 481  ? 178.733 193.047 144.871 1.00 138.43 ? 499  MET A CE  1 
ATOM   3624 N N   . VAL A 1 482  ? 178.766 187.077 143.095 1.00 100.83 ? 500  VAL A N   1 
ATOM   3625 C CA  . VAL A 1 482  ? 178.286 185.753 143.470 1.00 94.71  ? 500  VAL A CA  1 
ATOM   3626 C C   . VAL A 1 482  ? 178.545 185.553 144.953 1.00 95.83  ? 500  VAL A C   1 
ATOM   3627 O O   . VAL A 1 482  ? 179.675 185.748 145.424 1.00 106.93 ? 500  VAL A O   1 
ATOM   3628 C CB  . VAL A 1 482  ? 178.958 184.650 142.639 1.00 100.75 ? 500  VAL A CB  1 
ATOM   3629 C CG1 . VAL A 1 482  ? 178.302 183.298 142.914 1.00 106.73 ? 500  VAL A CG1 1 
ATOM   3630 C CG2 . VAL A 1 482  ? 178.896 185.008 141.162 1.00 111.22 ? 500  VAL A CG2 1 
ATOM   3631 N N   . VAL A 1 483  ? 177.500 185.142 145.672 1.00 91.69  ? 501  VAL A N   1 
ATOM   3632 C CA  . VAL A 1 483  ? 177.505 184.989 147.122 1.00 95.73  ? 501  VAL A CA  1 
ATOM   3633 C C   . VAL A 1 483  ? 177.056 183.571 147.447 1.00 100.09 ? 501  VAL A C   1 
ATOM   3634 O O   . VAL A 1 483  ? 176.122 183.053 146.825 1.00 104.77 ? 501  VAL A O   1 
ATOM   3635 C CB  . VAL A 1 483  ? 176.580 186.018 147.801 1.00 98.14  ? 501  VAL A CB  1 
ATOM   3636 C CG1 . VAL A 1 483  ? 176.424 185.710 149.283 1.00 102.64 ? 501  VAL A CG1 1 
ATOM   3637 C CG2 . VAL A 1 483  ? 177.104 187.435 147.608 1.00 107.66 ? 501  VAL A CG2 1 
ATOM   3638 N N   . SER A 1 484  ? 177.723 182.942 148.413 1.00 98.53  ? 502  SER A N   1 
ATOM   3639 C CA  . SER A 1 484  ? 177.360 181.604 148.854 1.00 97.25  ? 502  SER A CA  1 
ATOM   3640 C C   . SER A 1 484  ? 177.808 181.406 150.293 1.00 101.54 ? 502  SER A C   1 
ATOM   3641 O O   . SER A 1 484  ? 178.843 181.928 150.714 1.00 106.20 ? 502  SER A O   1 
ATOM   3642 C CB  . SER A 1 484  ? 177.986 180.528 147.966 1.00 103.80 ? 502  SER A CB  1 
ATOM   3643 O OG  . SER A 1 484  ? 179.245 180.129 148.476 1.00 108.89 ? 502  SER A OG  1 
ATOM   3644 N N   . ARG A 1 485  ? 177.015 180.637 151.041 1.00 104.13 ? 503  ARG A N   1 
ATOM   3645 C CA  . ARG A 1 485  ? 177.263 180.378 152.461 1.00 109.29 ? 503  ARG A CA  1 
ATOM   3646 C C   . ARG A 1 485  ? 177.351 181.675 153.260 1.00 111.47 ? 503  ARG A C   1 
ATOM   3647 O O   . ARG A 1 485  ? 178.089 181.760 154.244 1.00 111.25 ? 503  ARG A O   1 
ATOM   3648 C CB  . ARG A 1 485  ? 178.537 179.556 152.667 1.00 106.10 ? 503  ARG A CB  1 
ATOM   3649 C CG  . ARG A 1 485  ? 178.596 178.257 151.886 1.00 104.26 ? 503  ARG A CG  1 
ATOM   3650 C CD  . ARG A 1 485  ? 179.878 177.510 152.204 1.00 100.92 ? 503  ARG A CD  1 
ATOM   3651 N NE  . ARG A 1 485  ? 180.142 176.428 151.263 1.00 101.43 ? 503  ARG A NE  1 
ATOM   3652 C CZ  . ARG A 1 485  ? 181.317 175.832 151.099 1.00 109.24 ? 503  ARG A CZ  1 
ATOM   3653 N NH1 . ARG A 1 485  ? 182.376 176.161 151.824 1.00 112.75 ? 503  ARG A NH1 1 
ATOM   3654 N NH2 . ARG A 1 485  ? 181.437 174.880 150.179 1.00 116.33 ? 503  ARG A NH2 1 
ATOM   3655 N N   . GLY A 1 486  ? 176.603 182.692 152.846 1.00 112.21 ? 504  GLY A N   1 
ATOM   3656 C CA  . GLY A 1 486  ? 176.712 183.995 153.471 1.00 117.50 ? 504  GLY A CA  1 
ATOM   3657 C C   . GLY A 1 486  ? 178.080 184.623 153.334 1.00 115.70 ? 504  GLY A C   1 
ATOM   3658 O O   . GLY A 1 486  ? 178.501 185.371 154.221 1.00 116.27 ? 504  GLY A O   1 
ATOM   3659 N N   . GLN A 1 487  ? 178.787 184.333 152.243 1.00 111.64 ? 505  GLN A N   1 
ATOM   3660 C CA  . GLN A 1 487  ? 180.098 184.900 151.966 1.00 105.88 ? 505  GLN A CA  1 
ATOM   3661 C C   . GLN A 1 487  ? 180.145 185.311 150.505 1.00 107.10 ? 505  GLN A C   1 
ATOM   3662 O O   . GLN A 1 487  ? 179.664 184.583 149.633 1.00 110.03 ? 505  GLN A O   1 
ATOM   3663 C CB  . GLN A 1 487  ? 181.219 183.898 152.270 1.00 104.70 ? 505  GLN A CB  1 
ATOM   3664 C CG  . GLN A 1 487  ? 182.610 184.512 152.330 1.00 114.73 ? 505  GLN A CG  1 
ATOM   3665 C CD  . GLN A 1 487  ? 183.707 183.480 152.170 1.00 126.49 ? 505  GLN A CD  1 
ATOM   3666 O OE1 . GLN A 1 487  ? 183.612 182.371 152.694 1.00 128.79 ? 505  GLN A OE1 1 
ATOM   3667 N NE2 . GLN A 1 487  ? 184.756 183.840 151.441 1.00 129.30 ? 505  GLN A NE2 1 
ATOM   3668 N N   . LEU A 1 488  ? 180.726 186.477 150.243 1.00 102.92 ? 506  LEU A N   1 
ATOM   3669 C CA  . LEU A 1 488  ? 180.814 187.016 148.889 1.00 97.84  ? 506  LEU A CA  1 
ATOM   3670 C C   . LEU A 1 488  ? 182.011 186.377 148.201 1.00 102.57 ? 506  LEU A C   1 
ATOM   3671 O O   . LEU A 1 488  ? 183.151 186.807 148.386 1.00 110.86 ? 506  LEU A O   1 
ATOM   3672 C CB  . LEU A 1 488  ? 180.934 188.534 148.934 1.00 100.37 ? 506  LEU A CB  1 
ATOM   3673 C CG  . LEU A 1 488  ? 181.034 189.261 147.595 1.00 108.59 ? 506  LEU A CG  1 
ATOM   3674 C CD1 . LEU A 1 488  ? 179.899 190.258 147.450 1.00 119.63 ? 506  LEU A CD1 1 
ATOM   3675 C CD2 . LEU A 1 488  ? 182.373 189.961 147.471 1.00 116.18 ? 506  LEU A CD2 1 
ATOM   3676 N N   . VAL A 1 489  ? 181.749 185.351 147.385 1.00 100.10 ? 507  VAL A N   1 
ATOM   3677 C CA  . VAL A 1 489  ? 182.814 184.508 146.848 1.00 96.08  ? 507  VAL A CA  1 
ATOM   3678 C C   . VAL A 1 489  ? 183.293 184.934 145.467 1.00 95.48  ? 507  VAL A C   1 
ATOM   3679 O O   . VAL A 1 489  ? 184.321 184.412 145.006 1.00 101.28 ? 507  VAL A O   1 
ATOM   3680 C CB  . VAL A 1 489  ? 182.388 183.024 146.800 1.00 97.75  ? 507  VAL A CB  1 
ATOM   3681 C CG1 . VAL A 1 489  ? 181.842 182.585 148.146 1.00 105.99 ? 507  VAL A CG1 1 
ATOM   3682 C CG2 . VAL A 1 489  ? 181.367 182.775 145.702 1.00 99.33  ? 507  VAL A CG2 1 
ATOM   3683 N N   . ALA A 1 490  ? 182.595 185.842 144.782 1.00 97.32  ? 508  ALA A N   1 
ATOM   3684 C CA  . ALA A 1 490  ? 183.109 186.298 143.496 1.00 100.18 ? 508  ALA A CA  1 
ATOM   3685 C C   . ALA A 1 490  ? 182.531 187.655 143.130 1.00 107.10 ? 508  ALA A C   1 
ATOM   3686 O O   . ALA A 1 490  ? 181.435 188.016 143.559 1.00 111.52 ? 508  ALA A O   1 
ATOM   3687 C CB  . ALA A 1 490  ? 182.802 185.297 142.377 1.00 99.36  ? 508  ALA A CB  1 
ATOM   3688 N N   . VAL A 1 491  ? 183.283 188.393 142.308 1.00 110.53 ? 509  VAL A N   1 
ATOM   3689 C CA  . VAL A 1 491  ? 182.840 189.655 141.730 1.00 114.53 ? 509  VAL A CA  1 
ATOM   3690 C C   . VAL A 1 491  ? 183.321 189.728 140.288 1.00 120.78 ? 509  VAL A C   1 
ATOM   3691 O O   . VAL A 1 491  ? 184.179 188.957 139.854 1.00 124.53 ? 509  VAL A O   1 
ATOM   3692 C CB  . VAL A 1 491  ? 183.356 190.886 142.512 1.00 116.53 ? 509  VAL A CB  1 
ATOM   3693 C CG1 . VAL A 1 491  ? 182.695 190.964 143.872 1.00 116.09 ? 509  VAL A CG1 1 
ATOM   3694 C CG2 . VAL A 1 491  ? 184.878 190.868 142.645 1.00 126.05 ? 509  VAL A CG2 1 
ATOM   3695 N N   . GLY A 1 492  ? 182.755 190.670 139.545 1.00 121.83 ? 510  GLY A N   1 
ATOM   3696 C CA  . GLY A 1 492  ? 183.300 191.009 138.247 1.00 125.41 ? 510  GLY A CA  1 
ATOM   3697 C C   . GLY A 1 492  ? 182.344 191.883 137.467 1.00 129.98 ? 510  GLY A C   1 
ATOM   3698 O O   . GLY A 1 492  ? 181.253 192.226 137.932 1.00 130.44 ? 510  GLY A O   1 
ATOM   3699 N N   . LYS A 1 493  ? 182.786 192.242 136.263 1.00 134.10 ? 511  LYS A N   1 
ATOM   3700 C CA  . LYS A 1 493  ? 182.028 193.079 135.344 1.00 136.31 ? 511  LYS A CA  1 
ATOM   3701 C C   . LYS A 1 493  ? 181.879 192.365 134.009 1.00 138.47 ? 511  LYS A C   1 
ATOM   3702 O O   . LYS A 1 493  ? 182.827 191.744 133.517 1.00 132.37 ? 511  LYS A O   1 
ATOM   3703 C CB  . LYS A 1 493  ? 182.714 194.432 135.137 1.00 137.15 ? 511  LYS A CB  1 
ATOM   3704 C CG  . LYS A 1 493  ? 182.353 195.476 136.183 1.00 139.14 ? 511  LYS A CG  1 
ATOM   3705 C CD  . LYS A 1 493  ? 182.818 196.866 135.777 1.00 148.38 ? 511  LYS A CD  1 
ATOM   3706 C CE  . LYS A 1 493  ? 182.225 197.935 136.679 1.00 159.04 ? 511  LYS A CE  1 
ATOM   3707 N NZ  . LYS A 1 493  ? 182.597 199.308 136.241 1.00 170.02 ? 511  LYS A NZ  1 
ATOM   3708 N N   . GLN A 1 494  ? 180.682 192.459 133.432 1.00 142.73 ? 512  GLN A N   1 
ATOM   3709 C CA  . GLN A 1 494  ? 180.348 191.846 132.154 1.00 146.99 ? 512  GLN A CA  1 
ATOM   3710 C C   . GLN A 1 494  ? 179.901 192.936 131.193 1.00 155.20 ? 512  GLN A C   1 
ATOM   3711 O O   . GLN A 1 494  ? 179.002 193.723 131.514 1.00 156.43 ? 512  GLN A O   1 
ATOM   3712 C CB  . GLN A 1 494  ? 179.242 190.792 132.304 1.00 146.28 ? 512  GLN A CB  1 
ATOM   3713 C CG  . GLN A 1 494  ? 179.484 189.731 133.378 1.00 140.66 ? 512  GLN A CG  1 
ATOM   3714 C CD  . GLN A 1 494  ? 180.392 188.622 132.900 1.00 148.35 ? 512  GLN A CD  1 
ATOM   3715 O OE1 . GLN A 1 494  ? 181.149 188.794 131.945 1.00 153.43 ? 512  GLN A OE1 1 
ATOM   3716 N NE2 . GLN A 1 494  ? 180.327 187.476 133.566 1.00 145.63 ? 512  GLN A NE2 1 
ATOM   3717 N N   . ASN A 1 495  ? 180.531 192.981 130.018 1.00 155.76 ? 513  ASN A N   1 
ATOM   3718 C CA  . ASN A 1 495  ? 180.195 193.979 129.011 1.00 160.53 ? 513  ASN A CA  1 
ATOM   3719 C C   . ASN A 1 495  ? 178.993 193.583 128.164 1.00 161.37 ? 513  ASN A C   1 
ATOM   3720 O O   . ASN A 1 495  ? 178.318 194.466 127.625 1.00 160.74 ? 513  ASN A O   1 
ATOM   3721 C CB  . ASN A 1 495  ? 181.407 194.227 128.105 1.00 159.63 ? 513  ASN A CB  1 
ATOM   3722 C CG  . ASN A 1 495  ? 181.346 195.566 127.382 1.00 164.42 ? 513  ASN A CG  1 
ATOM   3723 O OD1 . ASN A 1 495  ? 180.514 196.421 127.686 1.00 167.81 ? 513  ASN A OD1 1 
ATOM   3724 N ND2 . ASN A 1 495  ? 182.243 195.753 126.421 1.00 156.75 ? 513  ASN A ND2 1 
ATOM   3725 N N   . SER A 1 496  ? 178.709 192.289 128.043 1.00 160.33 ? 514  SER A N   1 
ATOM   3726 C CA  . SER A 1 496  ? 177.644 191.781 127.191 1.00 162.17 ? 514  SER A CA  1 
ATOM   3727 C C   . SER A 1 496  ? 176.386 191.484 128.002 1.00 162.81 ? 514  SER A C   1 
ATOM   3728 O O   . SER A 1 496  ? 176.372 191.550 129.233 1.00 163.39 ? 514  SER A O   1 
ATOM   3729 C CB  . SER A 1 496  ? 178.108 190.518 126.463 1.00 159.21 ? 514  SER A CB  1 
ATOM   3730 O OG  . SER A 1 496  ? 177.016 189.866 125.839 1.00 158.43 ? 514  SER A OG  1 
ATOM   3731 N N   . THR A 1 497  ? 175.314 191.151 127.277 1.00 163.05 ? 515  THR A N   1 
ATOM   3732 C CA  . THR A 1 497  ? 174.065 190.661 127.852 1.00 161.19 ? 515  THR A CA  1 
ATOM   3733 C C   . THR A 1 497  ? 173.998 189.137 127.824 1.00 152.28 ? 515  THR A C   1 
ATOM   3734 O O   . THR A 1 497  ? 172.918 188.553 127.706 1.00 148.07 ? 515  THR A O   1 
ATOM   3735 C CB  . THR A 1 497  ? 172.872 191.266 127.113 1.00 167.14 ? 515  THR A CB  1 
ATOM   3736 O OG1 . THR A 1 497  ? 172.763 190.685 125.808 1.00 170.53 ? 515  THR A OG1 1 
ATOM   3737 C CG2 . THR A 1 497  ? 173.043 192.776 126.976 1.00 166.65 ? 515  THR A CG2 1 
ATOM   3738 N N   . MET A 1 498  ? 175.156 188.497 127.932 1.00 150.71 ? 516  MET A N   1 
ATOM   3739 C CA  . MET A 1 498  ? 175.331 187.065 127.726 1.00 150.61 ? 516  MET A CA  1 
ATOM   3740 C C   . MET A 1 498  ? 176.632 186.746 128.437 1.00 152.63 ? 516  MET A C   1 
ATOM   3741 O O   . MET A 1 498  ? 177.662 187.321 128.075 1.00 156.06 ? 516  MET A O   1 
ATOM   3742 C CB  . MET A 1 498  ? 175.434 186.732 126.240 1.00 151.01 ? 516  MET A CB  1 
ATOM   3743 C CG  . MET A 1 498  ? 174.960 185.351 125.752 1.00 155.66 ? 516  MET A CG  1 
ATOM   3744 S SD  . MET A 1 498  ? 173.637 184.377 126.516 1.00 170.58 ? 516  MET A SD  1 
ATOM   3745 C CE  . MET A 1 498  ? 172.331 185.543 126.880 1.00 153.14 ? 516  MET A CE  1 
ATOM   3746 N N   . PHE A 1 499  ? 176.606 185.881 129.451 1.00 149.04 ? 517  PHE A N   1 
ATOM   3747 C CA  . PHE A 1 499  ? 177.900 185.524 130.026 1.00 144.70 ? 517  PHE A CA  1 
ATOM   3748 C C   . PHE A 1 499  ? 177.849 184.182 130.726 1.00 141.62 ? 517  PHE A C   1 
ATOM   3749 O O   . PHE A 1 499  ? 176.835 183.805 131.308 1.00 145.24 ? 517  PHE A O   1 
ATOM   3750 C CB  . PHE A 1 499  ? 178.416 186.596 130.999 1.00 144.56 ? 517  PHE A CB  1 
ATOM   3751 C CG  . PHE A 1 499  ? 177.413 187.038 132.027 1.00 143.61 ? 517  PHE A CG  1 
ATOM   3752 C CD1 . PHE A 1 499  ? 177.242 186.324 133.200 1.00 139.90 ? 517  PHE A CD1 1 
ATOM   3753 C CD2 . PHE A 1 499  ? 176.653 188.176 131.828 1.00 147.71 ? 517  PHE A CD2 1 
ATOM   3754 C CE1 . PHE A 1 499  ? 176.332 186.733 134.150 1.00 136.82 ? 517  PHE A CE1 1 
ATOM   3755 C CE2 . PHE A 1 499  ? 175.739 188.589 132.776 1.00 149.04 ? 517  PHE A CE2 1 
ATOM   3756 C CZ  . PHE A 1 499  ? 175.579 187.866 133.938 1.00 142.61 ? 517  PHE A CZ  1 
ATOM   3757 N N   . SER A 1 500  ? 178.979 183.485 130.682 1.00 136.50 ? 518  SER A N   1 
ATOM   3758 C CA  . SER A 1 500  ? 179.147 182.181 131.300 1.00 136.58 ? 518  SER A CA  1 
ATOM   3759 C C   . SER A 1 500  ? 180.067 182.300 132.505 1.00 134.24 ? 518  SER A C   1 
ATOM   3760 O O   . SER A 1 500  ? 181.052 183.044 132.475 1.00 132.21 ? 518  SER A O   1 
ATOM   3761 C CB  . SER A 1 500  ? 179.718 181.172 130.302 1.00 138.44 ? 518  SER A CB  1 
ATOM   3762 O OG  . SER A 1 500  ? 180.953 181.623 129.774 1.00 146.99 ? 518  SER A OG  1 
ATOM   3763 N N   . LEU A 1 501  ? 179.731 181.563 133.562 1.00 131.12 ? 519  LEU A N   1 
ATOM   3764 C CA  . LEU A 1 501  ? 180.492 181.551 134.803 1.00 127.57 ? 519  LEU A CA  1 
ATOM   3765 C C   . LEU A 1 501  ? 180.847 180.118 135.163 1.00 130.97 ? 519  LEU A C   1 
ATOM   3766 O O   . LEU A 1 501  ? 180.107 179.182 134.850 1.00 136.40 ? 519  LEU A O   1 
ATOM   3767 C CB  . LEU A 1 501  ? 179.703 182.189 135.955 1.00 122.99 ? 519  LEU A CB  1 
ATOM   3768 C CG  . LEU A 1 501  ? 179.281 183.651 135.800 1.00 124.91 ? 519  LEU A CG  1 
ATOM   3769 C CD1 . LEU A 1 501  ? 178.524 184.108 137.036 1.00 120.67 ? 519  LEU A CD1 1 
ATOM   3770 C CD2 . LEU A 1 501  ? 180.479 184.554 135.547 1.00 123.60 ? 519  LEU A CD2 1 
ATOM   3771 N N   . THR A 1 502  ? 181.988 179.964 135.835 1.00 128.24 ? 520  THR A N   1 
ATOM   3772 C CA  . THR A 1 502  ? 182.510 178.663 136.237 1.00 126.99 ? 520  THR A CA  1 
ATOM   3773 C C   . THR A 1 502  ? 182.355 178.504 137.745 1.00 121.62 ? 520  THR A C   1 
ATOM   3774 O O   . THR A 1 502  ? 183.121 179.125 138.498 1.00 125.77 ? 520  THR A O   1 
ATOM   3775 C CB  . THR A 1 502  ? 183.981 178.534 135.842 1.00 133.37 ? 520  THR A CB  1 
ATOM   3776 O OG1 . THR A 1 502  ? 184.114 178.704 134.425 1.00 138.97 ? 520  THR A OG1 1 
ATOM   3777 C CG2 . THR A 1 502  ? 184.532 177.171 136.242 1.00 134.35 ? 520  THR A CG2 1 
ATOM   3778 N N   . PRO A 1 503  ? 181.405 177.715 138.250 1.00 116.37 ? 521  PRO A N   1 
ATOM   3779 C CA  . PRO A 1 503  ? 181.312 177.542 139.703 1.00 115.86 ? 521  PRO A CA  1 
ATOM   3780 C C   . PRO A 1 503  ? 182.499 176.777 140.264 1.00 121.02 ? 521  PRO A C   1 
ATOM   3781 O O   . PRO A 1 503  ? 183.133 175.971 139.579 1.00 124.36 ? 521  PRO A O   1 
ATOM   3782 C CB  . PRO A 1 503  ? 180.008 176.758 139.892 1.00 116.10 ? 521  PRO A CB  1 
ATOM   3783 C CG  . PRO A 1 503  ? 179.251 176.951 138.641 1.00 117.46 ? 521  PRO A CG  1 
ATOM   3784 C CD  . PRO A 1 503  ? 180.273 177.064 137.568 1.00 119.92 ? 521  PRO A CD  1 
ATOM   3785 N N   . GLU A 1 504  ? 182.787 177.045 141.535 1.00 119.85 ? 522  GLU A N   1 
ATOM   3786 C CA  . GLU A 1 504  ? 183.872 176.422 142.282 1.00 119.94 ? 522  GLU A CA  1 
ATOM   3787 C C   . GLU A 1 504  ? 183.287 175.680 143.483 1.00 118.30 ? 522  GLU A C   1 
ATOM   3788 O O   . GLU A 1 504  ? 182.076 175.694 143.718 1.00 120.70 ? 522  GLU A O   1 
ATOM   3789 C CB  . GLU A 1 504  ? 184.896 177.476 142.704 1.00 122.28 ? 522  GLU A CB  1 
ATOM   3790 C CG  . GLU A 1 504  ? 185.673 178.069 141.545 1.00 136.02 ? 522  GLU A CG  1 
ATOM   3791 C CD  . GLU A 1 504  ? 186.616 179.169 141.982 1.00 152.51 ? 522  GLU A CD  1 
ATOM   3792 O OE1 . GLU A 1 504  ? 186.725 179.409 143.203 1.00 154.66 ? 522  GLU A OE1 1 
ATOM   3793 O OE2 . GLU A 1 504  ? 187.249 179.794 141.106 1.00 158.86 ? 522  GLU A OE2 1 
ATOM   3794 N N   . ASN A 1 505  ? 184.164 175.023 144.246 1.00 118.78 ? 523  ASN A N   1 
ATOM   3795 C CA  . ASN A 1 505  ? 183.716 174.272 145.415 1.00 120.40 ? 523  ASN A CA  1 
ATOM   3796 C C   . ASN A 1 505  ? 183.072 175.179 146.453 1.00 117.80 ? 523  ASN A C   1 
ATOM   3797 O O   . ASN A 1 505  ? 182.128 174.764 147.135 1.00 118.73 ? 523  ASN A O   1 
ATOM   3798 C CB  . ASN A 1 505  ? 184.891 173.520 146.048 1.00 128.41 ? 523  ASN A CB  1 
ATOM   3799 C CG  . ASN A 1 505  ? 184.976 172.068 145.604 1.00 138.84 ? 523  ASN A CG  1 
ATOM   3800 O OD1 . ASN A 1 505  ? 184.425 171.680 144.574 1.00 140.94 ? 523  ASN A OD1 1 
ATOM   3801 N ND2 . ASN A 1 505  ? 185.678 171.258 146.386 1.00 139.36 ? 523  ASN A ND2 1 
ATOM   3802 N N   . SER A 1 506  ? 183.558 176.411 146.587 1.00 115.75 ? 524  SER A N   1 
ATOM   3803 C CA  . SER A 1 506  ? 183.021 177.340 147.571 1.00 114.41 ? 524  SER A CA  1 
ATOM   3804 C C   . SER A 1 506  ? 181.619 177.831 147.235 1.00 111.58 ? 524  SER A C   1 
ATOM   3805 O O   . SER A 1 506  ? 180.946 178.373 148.117 1.00 111.95 ? 524  SER A O   1 
ATOM   3806 C CB  . SER A 1 506  ? 183.954 178.543 147.712 1.00 111.48 ? 524  SER A CB  1 
ATOM   3807 O OG  . SER A 1 506  ? 183.330 179.583 148.442 1.00 116.53 ? 524  SER A OG  1 
ATOM   3808 N N   . TRP A 1 507  ? 181.161 177.663 145.994 1.00 108.35 ? 525  TRP A N   1 
ATOM   3809 C CA  . TRP A 1 507  ? 179.843 178.150 145.607 1.00 103.23 ? 525  TRP A CA  1 
ATOM   3810 C C   . TRP A 1 507  ? 178.712 177.296 146.163 1.00 104.72 ? 525  TRP A C   1 
ATOM   3811 O O   . TRP A 1 507  ? 177.590 177.793 146.301 1.00 110.89 ? 525  TRP A O   1 
ATOM   3812 C CB  . TRP A 1 507  ? 179.716 178.193 144.083 1.00 105.29 ? 525  TRP A CB  1 
ATOM   3813 C CG  . TRP A 1 507  ? 180.476 179.298 143.408 1.00 108.26 ? 525  TRP A CG  1 
ATOM   3814 C CD1 . TRP A 1 507  ? 181.654 179.857 143.809 1.00 111.14 ? 525  TRP A CD1 1 
ATOM   3815 C CD2 . TRP A 1 507  ? 180.109 179.966 142.199 1.00 104.98 ? 525  TRP A CD2 1 
ATOM   3816 N NE1 . TRP A 1 507  ? 182.042 180.831 142.925 1.00 111.73 ? 525  TRP A NE1 1 
ATOM   3817 C CE2 . TRP A 1 507  ? 181.109 180.918 141.926 1.00 108.07 ? 525  TRP A CE2 1 
ATOM   3818 C CE3 . TRP A 1 507  ? 179.032 179.850 141.317 1.00 104.30 ? 525  TRP A CE3 1 
ATOM   3819 C CZ2 . TRP A 1 507  ? 181.063 181.750 140.813 1.00 109.15 ? 525  TRP A CZ2 1 
ATOM   3820 C CZ3 . TRP A 1 507  ? 178.989 180.675 140.212 1.00 112.19 ? 525  TRP A CZ3 1 
ATOM   3821 C CH2 . TRP A 1 507  ? 179.997 181.611 139.969 1.00 112.77 ? 525  TRP A CH2 1 
ATOM   3822 N N   . THR A 1 508  ? 178.975 176.033 146.479 1.00 102.46 ? 526  THR A N   1 
ATOM   3823 C CA  . THR A 1 508  ? 177.907 175.124 146.855 1.00 105.34 ? 526  THR A CA  1 
ATOM   3824 C C   . THR A 1 508  ? 177.350 175.488 148.232 1.00 108.63 ? 526  THR A C   1 
ATOM   3825 O O   . THR A 1 508  ? 178.035 176.125 149.035 1.00 112.13 ? 526  THR A O   1 
ATOM   3826 C CB  . THR A 1 508  ? 178.417 173.687 146.874 1.00 112.16 ? 526  THR A CB  1 
ATOM   3827 O OG1 . THR A 1 508  ? 179.670 173.630 147.566 1.00 116.60 ? 526  THR A OG1 1 
ATOM   3828 C CG2 . THR A 1 508  ? 178.604 173.176 145.459 1.00 121.31 ? 526  THR A CG2 1 
ATOM   3829 N N   . PRO A 1 509  ? 176.099 175.091 148.539 1.00 108.53 ? 527  PRO A N   1 
ATOM   3830 C CA  . PRO A 1 509  ? 175.111 174.370 147.722 1.00 107.44 ? 527  PRO A CA  1 
ATOM   3831 C C   . PRO A 1 509  ? 174.233 175.302 146.896 1.00 111.83 ? 527  PRO A C   1 
ATOM   3832 O O   . PRO A 1 509  ? 173.788 174.935 145.813 1.00 117.67 ? 527  PRO A O   1 
ATOM   3833 C CB  . PRO A 1 509  ? 174.297 173.622 148.776 1.00 109.88 ? 527  PRO A CB  1 
ATOM   3834 C CG  . PRO A 1 509  ? 174.263 174.575 149.931 1.00 114.91 ? 527  PRO A CG  1 
ATOM   3835 C CD  . PRO A 1 509  ? 175.585 175.320 149.902 1.00 114.56 ? 527  PRO A CD  1 
ATOM   3836 N N   . LYS A 1 510  ? 173.977 176.508 147.398 1.00 109.01 ? 528  LYS A N   1 
ATOM   3837 C CA  . LYS A 1 510  ? 173.129 177.498 146.747 1.00 110.95 ? 528  LYS A CA  1 
ATOM   3838 C C   . LYS A 1 510  ? 173.928 178.778 146.568 1.00 109.21 ? 528  LYS A C   1 
ATOM   3839 O O   . LYS A 1 510  ? 174.646 179.194 147.482 1.00 113.29 ? 528  LYS A O   1 
ATOM   3840 C CB  . LYS A 1 510  ? 171.874 177.771 147.576 1.00 120.07 ? 528  LYS A CB  1 
ATOM   3841 C CG  . LYS A 1 510  ? 170.741 178.415 146.787 1.00 128.49 ? 528  LYS A CG  1 
ATOM   3842 C CD  . LYS A 1 510  ? 169.506 178.708 147.648 1.00 146.78 ? 528  LYS A CD  1 
ATOM   3843 C CE  . LYS A 1 510  ? 168.883 177.462 148.278 1.00 155.77 ? 528  LYS A CE  1 
ATOM   3844 N NZ  . LYS A 1 510  ? 168.649 176.361 147.302 1.00 155.85 ? 528  LYS A NZ  1 
ATOM   3845 N N   . ALA A 1 511  ? 173.803 179.392 145.394 1.00 107.52 ? 529  ALA A N   1 
ATOM   3846 C CA  . ALA A 1 511  ? 174.544 180.596 145.041 1.00 108.83 ? 529  ALA A CA  1 
ATOM   3847 C C   . ALA A 1 511  ? 173.575 181.687 144.616 1.00 114.70 ? 529  ALA A C   1 
ATOM   3848 O O   . ALA A 1 511  ? 172.722 181.464 143.750 1.00 118.60 ? 529  ALA A O   1 
ATOM   3849 C CB  . ALA A 1 511  ? 175.540 180.315 143.916 1.00 109.05 ? 529  ALA A CB  1 
ATOM   3850 N N   . CYS A 1 512  ? 173.705 182.857 145.237 1.00 113.20 ? 530  CYS A N   1 
ATOM   3851 C CA  . CYS A 1 512  ? 173.064 184.073 144.759 1.00 116.18 ? 530  CYS A CA  1 
ATOM   3852 C C   . CYS A 1 512  ? 173.966 184.709 143.716 1.00 115.43 ? 530  CYS A C   1 
ATOM   3853 O O   . CYS A 1 512  ? 175.097 185.089 144.031 1.00 119.28 ? 530  CYS A O   1 
ATOM   3854 C CB  . CYS A 1 512  ? 172.837 185.069 145.892 1.00 119.73 ? 530  CYS A CB  1 
ATOM   3855 S SG  . CYS A 1 512  ? 171.484 184.729 147.007 1.00 159.42 ? 530  CYS A SG  1 
ATOM   3856 N N   . VAL A 1 513  ? 173.475 184.826 142.488 1.00 108.92 ? 531  VAL A N   1 
ATOM   3857 C CA  . VAL A 1 513  ? 174.107 185.641 141.459 1.00 107.55 ? 531  VAL A CA  1 
ATOM   3858 C C   . VAL A 1 513  ? 173.325 186.941 141.393 1.00 111.67 ? 531  VAL A C   1 
ATOM   3859 O O   . VAL A 1 513  ? 172.143 186.937 141.029 1.00 121.62 ? 531  VAL A O   1 
ATOM   3860 C CB  . VAL A 1 513  ? 174.122 184.926 140.100 1.00 114.15 ? 531  VAL A CB  1 
ATOM   3861 C CG1 . VAL A 1 513  ? 175.019 185.667 139.117 1.00 121.99 ? 531  VAL A CG1 1 
ATOM   3862 C CG2 . VAL A 1 513  ? 174.582 183.485 140.268 1.00 112.48 ? 531  VAL A CG2 1 
ATOM   3863 N N   . ILE A 1 514  ? 173.969 188.043 141.769 1.00 110.93 ? 532  ILE A N   1 
ATOM   3864 C CA  . ILE A 1 514  ? 173.339 189.356 141.838 1.00 109.47 ? 532  ILE A CA  1 
ATOM   3865 C C   . ILE A 1 514  ? 173.985 190.215 140.765 1.00 115.10 ? 532  ILE A C   1 
ATOM   3866 O O   . ILE A 1 514  ? 175.193 190.476 140.819 1.00 124.49 ? 532  ILE A O   1 
ATOM   3867 C CB  . ILE A 1 514  ? 173.490 190.005 143.226 1.00 108.65 ? 532  ILE A CB  1 
ATOM   3868 C CG1 . ILE A 1 514  ? 173.026 189.057 144.350 1.00 116.52 ? 532  ILE A CG1 1 
ATOM   3869 C CG2 . ILE A 1 514  ? 172.712 191.332 143.272 1.00 112.70 ? 532  ILE A CG2 1 
ATOM   3870 C CD1 . ILE A 1 514  ? 173.367 189.527 145.757 1.00 127.34 ? 532  ILE A CD1 1 
ATOM   3871 N N   . VAL A 1 515  ? 173.182 190.652 139.798 1.00 114.57 ? 533  VAL A N   1 
ATOM   3872 C CA  . VAL A 1 515  ? 173.630 191.519 138.714 1.00 118.04 ? 533  VAL A CA  1 
ATOM   3873 C C   . VAL A 1 515  ? 173.032 192.895 138.949 1.00 126.23 ? 533  VAL A C   1 
ATOM   3874 O O   . VAL A 1 515  ? 171.912 193.011 139.461 1.00 130.74 ? 533  VAL A O   1 
ATOM   3875 C CB  . VAL A 1 515  ? 173.237 190.971 137.325 1.00 118.21 ? 533  VAL A CB  1 
ATOM   3876 C CG1 . VAL A 1 515  ? 173.995 189.688 137.032 1.00 123.56 ? 533  VAL A CG1 1 
ATOM   3877 C CG2 . VAL A 1 515  ? 171.724 190.741 137.200 1.00 128.41 ? 533  VAL A CG2 1 
ATOM   3878 N N   . TYR A 1 516  ? 173.782 193.939 138.603 1.00 128.26 ? 534  TYR A N   1 
ATOM   3879 C CA  . TYR A 1 516  ? 173.287 195.290 138.812 1.00 135.81 ? 534  TYR A CA  1 
ATOM   3880 C C   . TYR A 1 516  ? 174.001 196.270 137.894 1.00 142.05 ? 534  TYR A C   1 
ATOM   3881 O O   . TYR A 1 516  ? 175.037 195.963 137.296 1.00 142.58 ? 534  TYR A O   1 
ATOM   3882 C CB  . TYR A 1 516  ? 173.439 195.721 140.277 1.00 136.43 ? 534  TYR A CB  1 
ATOM   3883 C CG  . TYR A 1 516  ? 174.861 195.820 140.784 1.00 136.00 ? 534  TYR A CG  1 
ATOM   3884 C CD1 . TYR A 1 516  ? 175.489 194.726 141.360 1.00 135.84 ? 534  TYR A CD1 1 
ATOM   3885 C CD2 . TYR A 1 516  ? 175.565 197.015 140.716 1.00 139.07 ? 534  TYR A CD2 1 
ATOM   3886 C CE1 . TYR A 1 516  ? 176.781 194.813 141.835 1.00 141.74 ? 534  TYR A CE1 1 
ATOM   3887 C CE2 . TYR A 1 516  ? 176.857 197.111 141.188 1.00 145.51 ? 534  TYR A CE2 1 
ATOM   3888 C CZ  . TYR A 1 516  ? 177.459 196.008 141.748 1.00 146.58 ? 534  TYR A CZ  1 
ATOM   3889 O OH  . TYR A 1 516  ? 178.748 196.099 142.220 1.00 151.79 ? 534  TYR A OH  1 
ATOM   3890 N N   . TYR A 1 517  ? 173.402 197.451 137.766 1.00 148.04 ? 535  TYR A N   1 
ATOM   3891 C CA  . TYR A 1 517  ? 174.033 198.565 137.073 1.00 155.98 ? 535  TYR A CA  1 
ATOM   3892 C C   . TYR A 1 517  ? 173.315 199.850 137.458 1.00 162.60 ? 535  TYR A C   1 
ATOM   3893 O O   . TYR A 1 517  ? 172.158 199.834 137.891 1.00 164.87 ? 535  TYR A O   1 
ATOM   3894 C CB  . TYR A 1 517  ? 174.030 198.367 135.552 1.00 160.43 ? 535  TYR A CB  1 
ATOM   3895 C CG  . TYR A 1 517  ? 172.751 198.779 134.862 1.00 167.27 ? 535  TYR A CG  1 
ATOM   3896 C CD1 . TYR A 1 517  ? 171.565 198.096 135.087 1.00 164.89 ? 535  TYR A CD1 1 
ATOM   3897 C CD2 . TYR A 1 517  ? 172.734 199.846 133.976 1.00 174.12 ? 535  TYR A CD2 1 
ATOM   3898 C CE1 . TYR A 1 517  ? 170.397 198.468 134.450 1.00 170.19 ? 535  TYR A CE1 1 
ATOM   3899 C CE2 . TYR A 1 517  ? 171.571 200.227 133.338 1.00 178.49 ? 535  TYR A CE2 1 
ATOM   3900 C CZ  . TYR A 1 517  ? 170.406 199.535 133.579 1.00 179.98 ? 535  TYR A CZ  1 
ATOM   3901 O OH  . TYR A 1 517  ? 169.245 199.911 132.944 1.00 188.18 ? 535  TYR A OH  1 
ATOM   3902 N N   . ILE A 1 518  ? 174.013 200.966 137.272 1.00 167.15 ? 536  ILE A N   1 
ATOM   3903 C CA  . ILE A 1 518  ? 173.517 202.275 137.670 1.00 176.25 ? 536  ILE A CA  1 
ATOM   3904 C C   . ILE A 1 518  ? 172.878 202.958 136.469 1.00 184.15 ? 536  ILE A C   1 
ATOM   3905 O O   . ILE A 1 518  ? 173.062 202.558 135.317 1.00 182.85 ? 536  ILE A O   1 
ATOM   3906 C CB  . ILE A 1 518  ? 174.629 203.163 138.289 1.00 178.34 ? 536  ILE A CB  1 
ATOM   3907 C CG1 . ILE A 1 518  ? 175.828 203.343 137.337 1.00 181.50 ? 536  ILE A CG1 1 
ATOM   3908 C CG2 . ILE A 1 518  ? 175.086 202.567 139.616 1.00 174.41 ? 536  ILE A CG2 1 
ATOM   3909 C CD1 . ILE A 1 518  ? 176.708 204.534 137.675 1.00 185.58 ? 536  ILE A CD1 1 
ATOM   3910 N N   . GLU A 1 519  ? 172.116 204.010 136.752 1.00 189.84 ? 537  GLU A N   1 
ATOM   3911 C CA  . GLU A 1 519  ? 171.513 204.873 135.748 1.00 197.97 ? 537  GLU A CA  1 
ATOM   3912 C C   . GLU A 1 519  ? 171.961 206.308 135.996 1.00 202.60 ? 537  GLU A C   1 
ATOM   3913 O O   . GLU A 1 519  ? 172.488 206.645 137.059 1.00 200.19 ? 537  GLU A O   1 
ATOM   3914 C CB  . GLU A 1 519  ? 169.982 204.769 135.780 1.00 198.89 ? 537  GLU A CB  1 
ATOM   3915 C CG  . GLU A 1 519  ? 169.303 204.787 134.413 1.00 202.66 ? 537  GLU A CG  1 
ATOM   3916 C CD  . GLU A 1 519  ? 169.644 203.575 133.563 1.00 201.57 ? 537  GLU A CD  1 
ATOM   3917 O OE1 . GLU A 1 519  ? 169.041 202.504 133.780 1.00 200.88 ? 537  GLU A OE1 1 
ATOM   3918 O OE2 . GLU A 1 519  ? 170.517 203.696 132.678 1.00 200.44 ? 537  GLU A OE2 1 
ATOM   3919 N N   . ASP A 1 520  ? 171.749 207.157 134.988 1.00 207.53 ? 538  ASP A N   1 
ATOM   3920 C CA  . ASP A 1 520  ? 172.263 208.521 135.036 1.00 211.97 ? 538  ASP A CA  1 
ATOM   3921 C C   . ASP A 1 520  ? 171.647 209.347 136.157 1.00 214.55 ? 538  ASP A C   1 
ATOM   3922 O O   . ASP A 1 520  ? 172.301 210.270 136.655 1.00 217.85 ? 538  ASP A O   1 
ATOM   3923 C CB  . ASP A 1 520  ? 172.027 209.216 133.695 1.00 212.20 ? 538  ASP A CB  1 
ATOM   3924 C CG  . ASP A 1 520  ? 172.684 208.487 132.539 1.00 211.28 ? 538  ASP A CG  1 
ATOM   3925 O OD1 . ASP A 1 520  ? 173.818 207.993 132.714 1.00 210.97 ? 538  ASP A OD1 1 
ATOM   3926 O OD2 . ASP A 1 520  ? 172.066 208.407 131.456 1.00 210.84 ? 538  ASP A OD2 1 
ATOM   3927 N N   . ASP A 1 521  ? 170.419 209.040 136.571 1.00 215.16 ? 539  ASP A N   1 
ATOM   3928 C CA  . ASP A 1 521  ? 169.757 209.762 137.651 1.00 220.86 ? 539  ASP A CA  1 
ATOM   3929 C C   . ASP A 1 521  ? 170.082 209.197 139.031 1.00 219.54 ? 539  ASP A C   1 
ATOM   3930 O O   . ASP A 1 521  ? 169.397 209.537 140.000 1.00 223.52 ? 539  ASP A O   1 
ATOM   3931 C CB  . ASP A 1 521  ? 168.239 209.762 137.439 1.00 223.38 ? 539  ASP A CB  1 
ATOM   3932 C CG  . ASP A 1 521  ? 167.636 208.371 137.492 1.00 219.81 ? 539  ASP A CG  1 
ATOM   3933 O OD1 . ASP A 1 521  ? 168.393 207.385 137.377 1.00 214.22 ? 539  ASP A OD1 1 
ATOM   3934 O OD2 . ASP A 1 521  ? 166.402 208.264 137.650 1.00 220.13 ? 539  ASP A OD2 1 
ATOM   3935 N N   . GLY A 1 522  ? 171.101 208.345 139.143 1.00 212.21 ? 540  GLY A N   1 
ATOM   3936 C CA  . GLY A 1 522  ? 171.465 207.748 140.409 1.00 209.17 ? 540  GLY A CA  1 
ATOM   3937 C C   . GLY A 1 522  ? 170.676 206.516 140.790 1.00 205.83 ? 540  GLY A C   1 
ATOM   3938 O O   . GLY A 1 522  ? 170.944 205.935 141.849 1.00 204.11 ? 540  GLY A O   1 
ATOM   3939 N N   . GLU A 1 523  ? 169.713 206.097 139.973 1.00 204.26 ? 541  GLU A N   1 
ATOM   3940 C CA  . GLU A 1 523  ? 168.948 204.894 140.265 1.00 199.33 ? 541  GLU A CA  1 
ATOM   3941 C C   . GLU A 1 523  ? 169.816 203.665 140.037 1.00 189.40 ? 541  GLU A C   1 
ATOM   3942 O O   . GLU A 1 523  ? 170.542 203.583 139.040 1.00 185.23 ? 541  GLU A O   1 
ATOM   3943 C CB  . GLU A 1 523  ? 167.696 204.830 139.392 1.00 204.21 ? 541  GLU A CB  1 
ATOM   3944 C CG  . GLU A 1 523  ? 166.783 203.647 139.704 1.00 203.02 ? 541  GLU A CG  1 
ATOM   3945 C CD  . GLU A 1 523  ? 165.420 203.750 139.040 1.00 208.41 ? 541  GLU A CD  1 
ATOM   3946 O OE1 . GLU A 1 523  ? 165.105 204.816 138.470 1.00 212.10 ? 541  GLU A OE1 1 
ATOM   3947 O OE2 . GLU A 1 523  ? 164.660 202.760 139.089 1.00 207.22 ? 541  GLU A OE2 1 
ATOM   3948 N N   . ILE A 1 524  ? 169.735 202.713 140.965 1.00 183.62 ? 542  ILE A N   1 
ATOM   3949 C CA  . ILE A 1 524  ? 170.470 201.452 140.892 1.00 175.90 ? 542  ILE A CA  1 
ATOM   3950 C C   . ILE A 1 524  ? 169.466 200.356 140.568 1.00 169.42 ? 542  ILE A C   1 
ATOM   3951 O O   . ILE A 1 524  ? 168.467 200.187 141.278 1.00 166.92 ? 542  ILE A O   1 
ATOM   3952 C CB  . ILE A 1 524  ? 171.244 201.168 142.200 1.00 173.76 ? 542  ILE A CB  1 
ATOM   3953 C CG1 . ILE A 1 524  ? 171.857 199.759 142.223 1.00 167.18 ? 542  ILE A CG1 1 
ATOM   3954 C CG2 . ILE A 1 524  ? 170.374 201.351 143.454 1.00 177.49 ? 542  ILE A CG2 1 
ATOM   3955 C CD1 . ILE A 1 524  ? 172.775 199.458 141.064 1.00 165.15 ? 542  ILE A CD1 1 
ATOM   3956 N N   . ILE A 1 525  ? 169.720 199.622 139.486 1.00 167.28 ? 543  ILE A N   1 
ATOM   3957 C CA  . ILE A 1 525  ? 168.806 198.616 138.959 1.00 163.91 ? 543  ILE A CA  1 
ATOM   3958 C C   . ILE A 1 525  ? 169.502 197.269 139.059 1.00 158.95 ? 543  ILE A C   1 
ATOM   3959 O O   . ILE A 1 525  ? 170.612 197.103 138.540 1.00 157.78 ? 543  ILE A O   1 
ATOM   3960 C CB  . ILE A 1 525  ? 168.402 198.929 137.506 1.00 168.44 ? 543  ILE A CB  1 
ATOM   3961 C CG1 . ILE A 1 525  ? 167.615 200.245 137.423 1.00 177.90 ? 543  ILE A CG1 1 
ATOM   3962 C CG2 . ILE A 1 525  ? 167.602 197.782 136.911 1.00 168.23 ? 543  ILE A CG2 1 
ATOM   3963 C CD1 . ILE A 1 525  ? 167.867 201.014 136.148 1.00 182.00 ? 543  ILE A CD1 1 
ATOM   3964 N N   . SER A 1 526  ? 168.841 196.307 139.704 1.00 153.68 ? 544  SER A N   1 
ATOM   3965 C CA  . SER A 1 526  ? 169.495 195.080 140.134 1.00 144.43 ? 544  SER A CA  1 
ATOM   3966 C C   . SER A 1 526  ? 168.520 193.914 140.067 1.00 139.02 ? 544  SER A C   1 
ATOM   3967 O O   . SER A 1 526  ? 167.301 194.094 140.022 1.00 145.40 ? 544  SER A O   1 
ATOM   3968 C CB  . SER A 1 526  ? 170.042 195.226 141.557 1.00 146.90 ? 544  SER A CB  1 
ATOM   3969 O OG  . SER A 1 526  ? 169.150 195.974 142.361 1.00 153.28 ? 544  SER A OG  1 
ATOM   3970 N N   . ASP A 1 527  ? 169.085 192.708 140.061 1.00 132.13 ? 545  ASP A N   1 
ATOM   3971 C CA  . ASP A 1 527  ? 168.307 191.478 140.067 1.00 134.71 ? 545  ASP A CA  1 
ATOM   3972 C C   . ASP A 1 527  ? 169.149 190.368 140.682 1.00 131.02 ? 545  ASP A C   1 
ATOM   3973 O O   . ASP A 1 527  ? 170.382 190.407 140.631 1.00 133.72 ? 545  ASP A O   1 
ATOM   3974 C CB  . ASP A 1 527  ? 167.855 191.098 138.651 1.00 143.16 ? 545  ASP A CB  1 
ATOM   3975 C CG  . ASP A 1 527  ? 166.969 189.867 138.624 1.00 147.31 ? 545  ASP A CG  1 
ATOM   3976 O OD1 . ASP A 1 527  ? 166.452 189.478 139.693 1.00 142.61 ? 545  ASP A OD1 1 
ATOM   3977 O OD2 . ASP A 1 527  ? 166.789 189.288 137.532 1.00 150.45 ? 545  ASP A OD2 1 
ATOM   3978 N N   . VAL A 1 528  ? 168.464 189.384 141.271 1.00 125.14 ? 546  VAL A N   1 
ATOM   3979 C CA  . VAL A 1 528  ? 169.093 188.235 141.910 1.00 125.76 ? 546  VAL A CA  1 
ATOM   3980 C C   . VAL A 1 528  ? 168.660 186.971 141.185 1.00 123.57 ? 546  VAL A C   1 
ATOM   3981 O O   . VAL A 1 528  ? 167.658 186.943 140.467 1.00 126.55 ? 546  VAL A O   1 
ATOM   3982 C CB  . VAL A 1 528  ? 168.748 188.124 143.413 1.00 132.31 ? 546  VAL A CB  1 
ATOM   3983 C CG1 . VAL A 1 528  ? 169.294 189.310 144.177 1.00 146.82 ? 546  VAL A CG1 1 
ATOM   3984 C CG2 . VAL A 1 528  ? 167.234 187.978 143.641 1.00 138.03 ? 546  VAL A CG2 1 
ATOM   3985 N N   . LEU A 1 529  ? 169.442 185.914 141.384 1.00 120.80 ? 547  LEU A N   1 
ATOM   3986 C CA  . LEU A 1 529  ? 169.047 184.577 140.958 1.00 116.16 ? 547  LEU A CA  1 
ATOM   3987 C C   . LEU A 1 529  ? 169.692 183.580 141.907 1.00 118.38 ? 547  LEU A C   1 
ATOM   3988 O O   . LEU A 1 529  ? 170.921 183.539 142.016 1.00 121.59 ? 547  LEU A O   1 
ATOM   3989 C CB  . LEU A 1 529  ? 169.469 184.305 139.511 1.00 118.79 ? 547  LEU A CB  1 
ATOM   3990 C CG  . LEU A 1 529  ? 169.084 182.946 138.916 1.00 114.95 ? 547  LEU A CG  1 
ATOM   3991 C CD1 . LEU A 1 529  ? 167.574 182.807 138.811 1.00 120.05 ? 547  LEU A CD1 1 
ATOM   3992 C CD2 . LEU A 1 529  ? 169.731 182.744 137.557 1.00 123.22 ? 547  LEU A CD2 1 
ATOM   3993 N N   . LYS A 1 530  ? 168.869 182.795 142.597 1.00 119.24 ? 548  LYS A N   1 
ATOM   3994 C CA  . LYS A 1 530  ? 169.339 181.753 143.502 1.00 119.67 ? 548  LYS A CA  1 
ATOM   3995 C C   . LYS A 1 530  ? 169.366 180.432 142.747 1.00 115.72 ? 548  LYS A C   1 
ATOM   3996 O O   . LYS A 1 530  ? 168.312 179.928 142.345 1.00 112.49 ? 548  LYS A O   1 
ATOM   3997 C CB  . LYS A 1 530  ? 168.438 181.650 144.732 1.00 118.69 ? 548  LYS A CB  1 
ATOM   3998 C CG  . LYS A 1 530  ? 168.291 182.951 145.502 1.00 127.03 ? 548  LYS A CG  1 
ATOM   3999 C CD  . LYS A 1 530  ? 167.855 182.705 146.938 1.00 141.34 ? 548  LYS A CD  1 
ATOM   4000 C CE  . LYS A 1 530  ? 167.734 184.008 147.713 1.00 161.33 ? 548  LYS A CE  1 
ATOM   4001 N NZ  . LYS A 1 530  ? 167.259 183.794 149.108 1.00 161.43 ? 548  LYS A NZ  1 
ATOM   4002 N N   . ILE A 1 531  ? 170.563 179.876 142.568 1.00 116.83 ? 549  ILE A N   1 
ATOM   4003 C CA  . ILE A 1 531  ? 170.761 178.652 141.789 1.00 115.17 ? 549  ILE A CA  1 
ATOM   4004 C C   . ILE A 1 531  ? 171.347 177.576 142.701 1.00 117.45 ? 549  ILE A C   1 
ATOM   4005 O O   . ILE A 1 531  ? 172.305 177.866 143.432 1.00 118.00 ? 549  ILE A O   1 
ATOM   4006 C CB  . ILE A 1 531  ? 171.680 178.887 140.573 1.00 112.00 ? 549  ILE A CB  1 
ATOM   4007 C CG1 . ILE A 1 531  ? 172.965 179.633 140.958 1.00 110.10 ? 549  ILE A CG1 1 
ATOM   4008 C CG2 . ILE A 1 531  ? 170.958 179.674 139.476 1.00 117.22 ? 549  ILE A CG2 1 
ATOM   4009 C CD1 . ILE A 1 531  ? 173.904 179.850 139.794 1.00 118.70 ? 549  ILE A CD1 1 
ATOM   4010 N N   . PRO A 1 532  ? 170.830 176.342 142.721 1.00 117.03 ? 550  PRO A N   1 
ATOM   4011 C CA  . PRO A 1 532  ? 171.576 175.266 143.383 1.00 117.17 ? 550  PRO A CA  1 
ATOM   4012 C C   . PRO A 1 532  ? 172.710 174.780 142.498 1.00 118.98 ? 550  PRO A C   1 
ATOM   4013 O O   . PRO A 1 532  ? 172.574 174.696 141.275 1.00 121.39 ? 550  PRO A O   1 
ATOM   4014 C CB  . PRO A 1 532  ? 170.521 174.175 143.597 1.00 116.99 ? 550  PRO A CB  1 
ATOM   4015 C CG  . PRO A 1 532  ? 169.538 174.389 142.533 1.00 118.54 ? 550  PRO A CG  1 
ATOM   4016 C CD  . PRO A 1 532  ? 169.523 175.857 142.232 1.00 115.70 ? 550  PRO A CD  1 
ATOM   4017 N N   . VAL A 1 533  ? 173.835 174.458 143.131 1.00 118.71 ? 551  VAL A N   1 
ATOM   4018 C CA  . VAL A 1 533  ? 175.054 174.045 142.442 1.00 115.70 ? 551  VAL A CA  1 
ATOM   4019 C C   . VAL A 1 533  ? 175.364 172.615 142.856 1.00 118.53 ? 551  VAL A C   1 
ATOM   4020 O O   . VAL A 1 533  ? 175.555 172.335 144.045 1.00 119.22 ? 551  VAL A O   1 
ATOM   4021 C CB  . VAL A 1 533  ? 176.234 174.975 142.763 1.00 110.63 ? 551  VAL A CB  1 
ATOM   4022 C CG1 . VAL A 1 533  ? 177.523 174.428 142.162 1.00 116.28 ? 551  VAL A CG1 1 
ATOM   4023 C CG2 . VAL A 1 533  ? 175.957 176.384 142.259 1.00 112.15 ? 551  VAL A CG2 1 
ATOM   4024 N N   . GLN A 1 534  ? 175.407 171.713 141.880 1.00 123.23 ? 552  GLN A N   1 
ATOM   4025 C CA  . GLN A 1 534  ? 175.833 170.348 142.147 1.00 127.01 ? 552  GLN A CA  1 
ATOM   4026 C C   . GLN A 1 534  ? 177.326 170.324 142.445 1.00 122.70 ? 552  GLN A C   1 
ATOM   4027 O O   . GLN A 1 534  ? 178.119 170.992 141.776 1.00 123.64 ? 552  GLN A O   1 
ATOM   4028 C CB  . GLN A 1 534  ? 175.511 169.450 140.953 1.00 137.88 ? 552  GLN A CB  1 
ATOM   4029 C CG  . GLN A 1 534  ? 175.643 167.959 141.228 1.00 144.45 ? 552  GLN A CG  1 
ATOM   4030 C CD  . GLN A 1 534  ? 175.527 167.126 139.967 1.00 151.95 ? 552  GLN A CD  1 
ATOM   4031 O OE1 . GLN A 1 534  ? 175.141 167.628 138.912 1.00 151.37 ? 552  GLN A OE1 1 
ATOM   4032 N NE2 . GLN A 1 534  ? 175.860 165.846 140.070 1.00 155.53 ? 552  GLN A NE2 1 
ATOM   4033 N N   . LEU A 1 535  ? 177.707 169.543 143.452 1.00 119.22 ? 553  LEU A N   1 
ATOM   4034 C CA  . LEU A 1 535  ? 179.084 169.470 143.925 1.00 120.38 ? 553  LEU A CA  1 
ATOM   4035 C C   . LEU A 1 535  ? 179.765 168.247 143.325 1.00 128.53 ? 553  LEU A C   1 
ATOM   4036 O O   . LEU A 1 535  ? 179.219 167.140 143.379 1.00 136.65 ? 553  LEU A O   1 
ATOM   4037 C CB  . LEU A 1 535  ? 179.124 169.410 145.452 1.00 113.59 ? 553  LEU A CB  1 
ATOM   4038 C CG  . LEU A 1 535  ? 180.484 169.248 146.141 1.00 116.00 ? 553  LEU A CG  1 
ATOM   4039 C CD1 . LEU A 1 535  ? 181.472 170.344 145.762 1.00 119.63 ? 553  LEU A CD1 1 
ATOM   4040 C CD2 . LEU A 1 535  ? 180.284 169.222 147.645 1.00 112.85 ? 553  LEU A CD2 1 
ATOM   4041 N N   . VAL A 1 536  ? 180.946 168.454 142.746 1.00 123.95 ? 554  VAL A N   1 
ATOM   4042 C CA  . VAL A 1 536  ? 181.816 167.374 142.298 1.00 123.78 ? 554  VAL A CA  1 
ATOM   4043 C C   . VAL A 1 536  ? 183.217 167.655 142.821 1.00 123.03 ? 554  VAL A C   1 
ATOM   4044 O O   . VAL A 1 536  ? 183.698 168.792 142.790 1.00 123.63 ? 554  VAL A O   1 
ATOM   4045 C CB  . VAL A 1 536  ? 181.822 167.213 140.761 1.00 128.13 ? 554  VAL A CB  1 
ATOM   4046 C CG1 . VAL A 1 536  ? 180.407 166.994 140.246 1.00 131.84 ? 554  VAL A CG1 1 
ATOM   4047 C CG2 . VAL A 1 536  ? 182.473 168.412 140.080 1.00 129.93 ? 554  VAL A CG2 1 
ATOM   4048 N N   . PHE A 1 537  ? 183.869 166.604 143.305 1.00 124.90 ? 555  PHE A N   1 
ATOM   4049 C CA  . PHE A 1 537  ? 185.152 166.718 143.979 1.00 122.33 ? 555  PHE A CA  1 
ATOM   4050 C C   . PHE A 1 537  ? 186.297 166.524 142.995 1.00 125.98 ? 555  PHE A C   1 
ATOM   4051 O O   . PHE A 1 537  ? 186.259 165.645 142.131 1.00 128.78 ? 555  PHE A O   1 
ATOM   4052 C CB  . PHE A 1 537  ? 185.262 165.685 145.101 1.00 115.62 ? 555  PHE A CB  1 
ATOM   4053 C CG  . PHE A 1 537  ? 184.276 165.895 146.210 1.00 113.51 ? 555  PHE A CG  1 
ATOM   4054 C CD1 . PHE A 1 537  ? 184.397 166.974 147.064 1.00 111.03 ? 555  PHE A CD1 1 
ATOM   4055 C CD2 . PHE A 1 537  ? 183.225 165.016 146.393 1.00 113.14 ? 555  PHE A CD2 1 
ATOM   4056 C CE1 . PHE A 1 537  ? 183.492 167.170 148.082 1.00 111.51 ? 555  PHE A CE1 1 
ATOM   4057 C CE2 . PHE A 1 537  ? 182.316 165.207 147.411 1.00 114.52 ? 555  PHE A CE2 1 
ATOM   4058 C CZ  . PHE A 1 537  ? 182.449 166.285 148.256 1.00 113.47 ? 555  PHE A CZ  1 
ATOM   4059 N N   . LYS A 1 538  ? 187.325 167.359 143.138 1.00 123.65 ? 556  LYS A N   1 
ATOM   4060 C CA  . LYS A 1 538  ? 188.535 167.205 142.344 1.00 129.14 ? 556  LYS A CA  1 
ATOM   4061 C C   . LYS A 1 538  ? 189.354 165.988 142.753 1.00 131.52 ? 556  LYS A C   1 
ATOM   4062 O O   . LYS A 1 538  ? 190.195 165.540 141.966 1.00 133.25 ? 556  LYS A O   1 
ATOM   4063 C CB  . LYS A 1 538  ? 189.390 168.471 142.446 1.00 133.26 ? 556  LYS A CB  1 
ATOM   4064 C CG  . LYS A 1 538  ? 190.173 168.600 143.743 1.00 131.98 ? 556  LYS A CG  1 
ATOM   4065 C CD  . LYS A 1 538  ? 190.465 170.056 144.106 1.00 139.47 ? 556  LYS A CD  1 
ATOM   4066 C CE  . LYS A 1 538  ? 191.046 170.853 142.941 1.00 146.54 ? 556  LYS A CE  1 
ATOM   4067 N NZ  . LYS A 1 538  ? 191.659 172.131 143.397 1.00 153.39 ? 556  LYS A NZ  1 
ATOM   4068 N N   . ASN A 1 539  ? 189.129 165.450 143.949 1.00 127.14 ? 557  ASN A N   1 
ATOM   4069 C CA  . ASN A 1 539  ? 189.713 164.187 144.381 1.00 117.90 ? 557  ASN A CA  1 
ATOM   4070 C C   . ASN A 1 539  ? 188.714 163.071 144.117 1.00 116.64 ? 557  ASN A C   1 
ATOM   4071 O O   . ASN A 1 539  ? 187.538 163.190 144.479 1.00 117.62 ? 557  ASN A O   1 
ATOM   4072 C CB  . ASN A 1 539  ? 190.076 164.232 145.864 1.00 114.38 ? 557  ASN A CB  1 
ATOM   4073 C CG  . ASN A 1 539  ? 191.130 163.218 146.230 1.00 119.30 ? 557  ASN A CG  1 
ATOM   4074 O OD1 . ASN A 1 539  ? 191.271 162.191 145.569 1.00 125.14 ? 557  ASN A OD1 1 
ATOM   4075 N ND2 . ASN A 1 539  ? 191.883 163.500 147.284 1.00 117.84 ? 557  ASN A ND2 1 
ATOM   4076 N N   . LYS A 1 540  ? 189.183 161.993 143.493 1.00 115.84 ? 558  LYS A N   1 
ATOM   4077 C CA  . LYS A 1 540  ? 188.329 160.925 142.994 1.00 118.99 ? 558  LYS A CA  1 
ATOM   4078 C C   . LYS A 1 540  ? 188.790 159.579 143.535 1.00 117.18 ? 558  LYS A C   1 
ATOM   4079 O O   . LYS A 1 540  ? 189.987 159.342 143.719 1.00 120.73 ? 558  LYS A O   1 
ATOM   4080 C CB  . LYS A 1 540  ? 188.330 160.888 141.459 1.00 122.44 ? 558  LYS A CB  1 
ATOM   4081 C CG  . LYS A 1 540  ? 188.096 162.241 140.789 1.00 127.61 ? 558  LYS A CG  1 
ATOM   4082 C CD  . LYS A 1 540  ? 187.020 162.163 139.720 1.00 135.05 ? 558  LYS A CD  1 
ATOM   4083 C CE  . LYS A 1 540  ? 186.720 163.535 139.141 1.00 132.72 ? 558  LYS A CE  1 
ATOM   4084 N NZ  . LYS A 1 540  ? 185.827 164.329 140.026 1.00 125.29 ? 558  LYS A NZ  1 
ATOM   4085 N N   . ILE A 1 541  ? 187.817 158.704 143.789 1.00 108.21 ? 559  ILE A N   1 
ATOM   4086 C CA  . ILE A 1 541  ? 188.056 157.336 144.233 1.00 101.58 ? 559  ILE A CA  1 
ATOM   4087 C C   . ILE A 1 541  ? 187.242 156.406 143.347 1.00 104.91 ? 559  ILE A C   1 
ATOM   4088 O O   . ILE A 1 541  ? 186.090 156.710 143.018 1.00 105.35 ? 559  ILE A O   1 
ATOM   4089 C CB  . ILE A 1 541  ? 187.695 157.130 145.719 1.00 94.71  ? 559  ILE A CB  1 
ATOM   4090 C CG1 . ILE A 1 541  ? 187.752 155.639 146.082 1.00 88.37  ? 559  ILE A CG1 1 
ATOM   4091 C CG2 . ILE A 1 541  ? 186.318 157.711 146.039 1.00 100.34 ? 559  ILE A CG2 1 
ATOM   4092 C CD1 . ILE A 1 541  ? 187.919 155.360 147.558 1.00 82.48  ? 559  ILE A CD1 1 
ATOM   4093 N N   . LYS A 1 542  ? 187.843 155.285 142.955 1.00 105.85 ? 560  LYS A N   1 
ATOM   4094 C CA  . LYS A 1 542  ? 187.162 154.245 142.197 1.00 107.26 ? 560  LYS A CA  1 
ATOM   4095 C C   . LYS A 1 542  ? 187.428 152.891 142.836 1.00 107.95 ? 560  LYS A C   1 
ATOM   4096 O O   . LYS A 1 542  ? 188.571 152.571 143.173 1.00 110.70 ? 560  LYS A O   1 
ATOM   4097 C CB  . LYS A 1 542  ? 187.628 154.226 140.735 1.00 108.47 ? 560  LYS A CB  1 
ATOM   4098 C CG  . LYS A 1 542  ? 187.121 155.381 139.857 1.00 110.84 ? 560  LYS A CG  1 
ATOM   4099 C CD  . LYS A 1 542  ? 185.595 155.440 139.692 1.00 115.39 ? 560  LYS A CD  1 
ATOM   4100 C CE  . LYS A 1 542  ? 185.027 154.209 138.997 1.00 116.92 ? 560  LYS A CE  1 
ATOM   4101 N NZ  . LYS A 1 542  ? 183.564 154.335 138.756 1.00 118.99 ? 560  LYS A NZ  1 
ATOM   4102 N N   . LEU A 1 543  ? 186.367 152.103 143.000 1.00 103.35 ? 561  LEU A N   1 
ATOM   4103 C CA  . LEU A 1 543  ? 186.452 150.740 143.508 1.00 104.37 ? 561  LEU A CA  1 
ATOM   4104 C C   . LEU A 1 543  ? 186.080 149.766 142.400 1.00 108.61 ? 561  LEU A C   1 
ATOM   4105 O O   . LEU A 1 543  ? 185.160 150.026 141.619 1.00 112.41 ? 561  LEU A O   1 
ATOM   4106 C CB  . LEU A 1 543  ? 185.529 150.523 144.712 1.00 104.15 ? 561  LEU A CB  1 
ATOM   4107 C CG  . LEU A 1 543  ? 185.219 151.701 145.636 1.00 106.30 ? 561  LEU A CG  1 
ATOM   4108 C CD1 . LEU A 1 543  ? 184.208 151.275 146.687 1.00 98.80  ? 561  LEU A CD1 1 
ATOM   4109 C CD2 . LEU A 1 543  ? 186.478 152.229 146.296 1.00 104.31 ? 561  LEU A CD2 1 
ATOM   4110 N N   . TYR A 1 544  ? 186.806 148.653 142.333 1.00 105.33 ? 562  TYR A N   1 
ATOM   4111 C CA  . TYR A 1 544  ? 186.555 147.595 141.363 1.00 105.44 ? 562  TYR A CA  1 
ATOM   4112 C C   . TYR A 1 544  ? 186.578 146.252 142.072 1.00 108.84 ? 562  TYR A C   1 
ATOM   4113 O O   . TYR A 1 544  ? 187.487 145.978 142.863 1.00 113.20 ? 562  TYR A O   1 
ATOM   4114 C CB  . TYR A 1 544  ? 187.595 147.603 140.239 1.00 106.64 ? 562  TYR A CB  1 
ATOM   4115 C CG  . TYR A 1 544  ? 187.817 148.954 139.603 1.00 112.69 ? 562  TYR A CG  1 
ATOM   4116 C CD1 . TYR A 1 544  ? 186.883 149.494 138.732 1.00 118.36 ? 562  TYR A CD1 1 
ATOM   4117 C CD2 . TYR A 1 544  ? 188.967 149.684 139.865 1.00 109.96 ? 562  TYR A CD2 1 
ATOM   4118 C CE1 . TYR A 1 544  ? 187.084 150.726 138.145 1.00 121.98 ? 562  TYR A CE1 1 
ATOM   4119 C CE2 . TYR A 1 544  ? 189.177 150.917 139.282 1.00 112.40 ? 562  TYR A CE2 1 
ATOM   4120 C CZ  . TYR A 1 544  ? 188.233 151.433 138.423 1.00 121.26 ? 562  TYR A CZ  1 
ATOM   4121 O OH  . TYR A 1 544  ? 188.437 152.662 137.841 1.00 124.81 ? 562  TYR A OH  1 
ATOM   4122 N N   . TRP A 1 545  ? 185.579 145.423 141.788 1.00 102.02 ? 563  TRP A N   1 
ATOM   4123 C CA  . TRP A 1 545  ? 185.565 144.049 142.261 1.00 95.01  ? 563  TRP A CA  1 
ATOM   4124 C C   . TRP A 1 545  ? 186.283 143.148 141.264 1.00 98.28  ? 563  TRP A C   1 
ATOM   4125 O O   . TRP A 1 545  ? 186.271 143.392 140.055 1.00 102.64 ? 563  TRP A O   1 
ATOM   4126 C CB  . TRP A 1 545  ? 184.131 143.565 142.451 1.00 92.76  ? 563  TRP A CB  1 
ATOM   4127 C CG  . TRP A 1 545  ? 183.437 144.181 143.617 1.00 95.25  ? 563  TRP A CG  1 
ATOM   4128 C CD1 . TRP A 1 545  ? 182.344 144.992 143.581 1.00 100.55 ? 563  TRP A CD1 1 
ATOM   4129 C CD2 . TRP A 1 545  ? 183.779 144.029 144.998 1.00 91.25  ? 563  TRP A CD2 1 
ATOM   4130 N NE1 . TRP A 1 545  ? 181.984 145.358 144.853 1.00 97.07  ? 563  TRP A NE1 1 
ATOM   4131 C CE2 . TRP A 1 545  ? 182.851 144.780 145.741 1.00 93.22  ? 563  TRP A CE2 1 
ATOM   4132 C CE3 . TRP A 1 545  ? 184.781 143.333 145.677 1.00 93.64  ? 563  TRP A CE3 1 
ATOM   4133 C CZ2 . TRP A 1 545  ? 182.894 144.855 147.127 1.00 89.26  ? 563  TRP A CZ2 1 
ATOM   4134 C CZ3 . TRP A 1 545  ? 184.820 143.408 147.054 1.00 92.20  ? 563  TRP A CZ3 1 
ATOM   4135 C CH2 . TRP A 1 545  ? 183.885 144.165 147.764 1.00 88.07  ? 563  TRP A CH2 1 
ATOM   4136 N N   . SER A 1 546  ? 186.918 142.098 141.785 1.00 96.26  ? 564  SER A N   1 
ATOM   4137 C CA  . SER A 1 546  ? 187.547 141.122 140.903 1.00 97.71  ? 564  SER A CA  1 
ATOM   4138 C C   . SER A 1 546  ? 186.508 140.415 140.046 1.00 102.41 ? 564  SER A C   1 
ATOM   4139 O O   . SER A 1 546  ? 186.740 140.171 138.856 1.00 106.60 ? 564  SER A O   1 
ATOM   4140 C CB  . SER A 1 546  ? 188.343 140.109 141.720 1.00 104.47 ? 564  SER A CB  1 
ATOM   4141 O OG  . SER A 1 546  ? 189.363 139.515 140.937 1.00 108.39 ? 564  SER A OG  1 
ATOM   4142 N N   . LYS A 1 547  ? 185.365 140.075 140.635 1.00 102.07 ? 565  LYS A N   1 
ATOM   4143 C CA  . LYS A 1 547  ? 184.252 139.452 139.933 1.00 104.67 ? 565  LYS A CA  1 
ATOM   4144 C C   . LYS A 1 547  ? 182.965 140.156 140.326 1.00 104.12 ? 565  LYS A C   1 
ATOM   4145 O O   . LYS A 1 547  ? 182.784 140.532 141.487 1.00 104.33 ? 565  LYS A O   1 
ATOM   4146 C CB  . LYS A 1 547  ? 184.141 137.964 140.266 1.00 103.58 ? 565  LYS A CB  1 
ATOM   4147 C CG  . LYS A 1 547  ? 185.322 137.127 139.819 1.00 102.21 ? 565  LYS A CG  1 
ATOM   4148 C CD  . LYS A 1 547  ? 185.155 135.685 140.265 1.00 104.35 ? 565  LYS A CD  1 
ATOM   4149 C CE  . LYS A 1 547  ? 186.363 134.842 139.906 1.00 113.52 ? 565  LYS A CE  1 
ATOM   4150 N NZ  . LYS A 1 547  ? 186.251 133.459 140.447 1.00 122.71 ? 565  LYS A NZ  1 
ATOM   4151 N N   . VAL A 1 548  ? 182.071 140.337 139.355 1.00 102.31 ? 566  VAL A N   1 
ATOM   4152 C CA  . VAL A 1 548  ? 180.761 140.897 139.668 1.00 107.10 ? 566  VAL A CA  1 
ATOM   4153 C C   . VAL A 1 548  ? 179.936 139.886 140.454 1.00 110.66 ? 566  VAL A C   1 
ATOM   4154 O O   . VAL A 1 548  ? 179.194 140.252 141.373 1.00 113.62 ? 566  VAL A O   1 
ATOM   4155 C CB  . VAL A 1 548  ? 180.038 141.351 138.385 1.00 112.11 ? 566  VAL A CB  1 
ATOM   4156 C CG1 . VAL A 1 548  ? 178.797 142.171 138.735 1.00 105.73 ? 566  VAL A CG1 1 
ATOM   4157 C CG2 . VAL A 1 548  ? 180.977 142.170 137.496 1.00 111.88 ? 566  VAL A CG2 1 
ATOM   4158 N N   . LYS A 1 549  ? 180.048 138.607 140.099 1.00 106.54 ? 567  LYS A N   1 
ATOM   4159 C CA  . LYS A 1 549  ? 179.402 137.506 140.801 1.00 106.79 ? 567  LYS A CA  1 
ATOM   4160 C C   . LYS A 1 549  ? 180.480 136.563 141.313 1.00 111.65 ? 567  LYS A C   1 
ATOM   4161 O O   . LYS A 1 549  ? 181.398 136.206 140.568 1.00 108.56 ? 567  LYS A O   1 
ATOM   4162 C CB  . LYS A 1 549  ? 178.429 136.766 139.877 1.00 107.78 ? 567  LYS A CB  1 
ATOM   4163 C CG  . LYS A 1 549  ? 177.753 135.547 140.495 1.00 116.71 ? 567  LYS A CG  1 
ATOM   4164 C CD  . LYS A 1 549  ? 176.734 134.941 139.548 1.00 125.94 ? 567  LYS A CD  1 
ATOM   4165 C CE  . LYS A 1 549  ? 176.646 133.436 139.731 1.00 140.99 ? 567  LYS A CE  1 
ATOM   4166 N NZ  . LYS A 1 549  ? 175.469 132.849 139.036 1.00 148.82 ? 567  LYS A NZ  1 
ATOM   4167 N N   . ALA A 1 550  ? 180.366 136.164 142.579 1.00 121.17 ? 568  ALA A N   1 
ATOM   4168 C CA  . ALA A 1 550  ? 181.325 135.270 143.210 1.00 120.44 ? 568  ALA A CA  1 
ATOM   4169 C C   . ALA A 1 550  ? 180.588 134.294 144.113 1.00 124.64 ? 568  ALA A C   1 
ATOM   4170 O O   . ALA A 1 550  ? 179.499 134.587 144.609 1.00 126.57 ? 568  ALA A O   1 
ATOM   4171 C CB  . ALA A 1 550  ? 182.369 136.043 144.024 1.00 118.28 ? 568  ALA A CB  1 
ATOM   4172 N N   . GLU A 1 551  ? 181.192 133.127 144.315 1.00 127.73 ? 569  GLU A N   1 
ATOM   4173 C CA  . GLU A 1 551  ? 180.608 132.133 145.194 1.00 137.08 ? 569  GLU A CA  1 
ATOM   4174 C C   . GLU A 1 551  ? 180.862 132.513 146.653 1.00 136.95 ? 569  GLU A C   1 
ATOM   4175 O O   . GLU A 1 551  ? 181.764 133.302 146.945 1.00 134.07 ? 569  GLU A O   1 
ATOM   4176 C CB  . GLU A 1 551  ? 181.196 130.753 144.909 1.00 141.65 ? 569  GLU A CB  1 
ATOM   4177 C CG  . GLU A 1 551  ? 181.082 130.289 143.459 1.00 149.26 ? 569  GLU A CG  1 
ATOM   4178 C CD  . GLU A 1 551  ? 179.647 130.208 142.973 1.00 155.29 ? 569  GLU A CD  1 
ATOM   4179 O OE1 . GLU A 1 551  ? 178.799 129.655 143.704 1.00 157.58 ? 569  GLU A OE1 1 
ATOM   4180 O OE2 . GLU A 1 551  ? 179.368 130.696 141.857 1.00 155.97 ? 569  GLU A OE2 1 
ATOM   4181 N N   . PRO A 1 552  ? 180.078 131.978 147.593 1.00 138.04 ? 570  PRO A N   1 
ATOM   4182 C CA  . PRO A 1 552  ? 180.410 132.183 149.007 1.00 133.42 ? 570  PRO A CA  1 
ATOM   4183 C C   . PRO A 1 552  ? 181.747 131.557 149.362 1.00 139.08 ? 570  PRO A C   1 
ATOM   4184 O O   . PRO A 1 552  ? 182.141 130.523 148.819 1.00 147.67 ? 570  PRO A O   1 
ATOM   4185 C CB  . PRO A 1 552  ? 179.261 131.492 149.750 1.00 134.06 ? 570  PRO A CB  1 
ATOM   4186 C CG  . PRO A 1 552  ? 178.150 131.458 148.789 1.00 138.36 ? 570  PRO A CG  1 
ATOM   4187 C CD  . PRO A 1 552  ? 178.781 131.293 147.445 1.00 140.04 ? 570  PRO A CD  1 
ATOM   4188 N N   . SER A 1 553  ? 182.443 132.199 150.301 1.00 137.81 ? 571  SER A N   1 
ATOM   4189 C CA  . SER A 1 553  ? 183.740 131.726 150.787 1.00 138.39 ? 571  SER A CA  1 
ATOM   4190 C C   . SER A 1 553  ? 184.752 131.629 149.647 1.00 137.32 ? 571  SER A C   1 
ATOM   4191 O O   . SER A 1 553  ? 185.512 130.664 149.540 1.00 138.51 ? 571  SER A O   1 
ATOM   4192 C CB  . SER A 1 553  ? 183.597 130.382 151.505 1.00 140.39 ? 571  SER A CB  1 
ATOM   4193 O OG  . SER A 1 553  ? 183.361 129.329 150.585 1.00 147.81 ? 571  SER A OG  1 
ATOM   4194 N N   . GLU A 1 554  ? 184.750 132.646 148.788 1.00 133.28 ? 572  GLU A N   1 
ATOM   4195 C CA  . GLU A 1 554  ? 185.665 132.754 147.660 1.00 128.74 ? 572  GLU A CA  1 
ATOM   4196 C C   . GLU A 1 554  ? 186.515 134.004 147.824 1.00 124.60 ? 572  GLU A C   1 
ATOM   4197 O O   . GLU A 1 554  ? 186.012 135.061 148.215 1.00 123.64 ? 572  GLU A O   1 
ATOM   4198 C CB  . GLU A 1 554  ? 184.901 132.810 146.335 1.00 127.42 ? 572  GLU A CB  1 
ATOM   4199 C CG  . GLU A 1 554  ? 185.765 132.570 145.110 1.00 131.27 ? 572  GLU A CG  1 
ATOM   4200 C CD  . GLU A 1 554  ? 184.965 132.586 143.823 1.00 137.26 ? 572  GLU A CD  1 
ATOM   4201 O OE1 . GLU A 1 554  ? 183.726 132.724 143.894 1.00 138.66 ? 572  GLU A OE1 1 
ATOM   4202 O OE2 . GLU A 1 554  ? 185.575 132.461 142.740 1.00 136.48 ? 572  GLU A OE2 1 
ATOM   4203 N N   . LYS A 1 555  ? 187.805 133.878 147.529 1.00 123.38 ? 573  LYS A N   1 
ATOM   4204 C CA  . LYS A 1 555  ? 188.730 134.994 147.675 1.00 118.79 ? 573  LYS A CA  1 
ATOM   4205 C C   . LYS A 1 555  ? 188.507 135.980 146.536 1.00 112.81 ? 573  LYS A C   1 
ATOM   4206 O O   . LYS A 1 555  ? 188.595 135.608 145.361 1.00 113.12 ? 573  LYS A O   1 
ATOM   4207 C CB  . LYS A 1 555  ? 190.173 134.496 147.689 1.00 120.82 ? 573  LYS A CB  1 
ATOM   4208 C CG  . LYS A 1 555  ? 190.485 133.496 148.798 1.00 123.54 ? 573  LYS A CG  1 
ATOM   4209 C CD  . LYS A 1 555  ? 191.444 134.080 149.820 1.00 137.02 ? 573  LYS A CD  1 
ATOM   4210 C CE  . LYS A 1 555  ? 191.676 133.119 150.974 1.00 146.70 ? 573  LYS A CE  1 
ATOM   4211 N NZ  . LYS A 1 555  ? 190.496 133.038 151.879 1.00 141.45 ? 573  LYS A NZ  1 
ATOM   4212 N N   . VAL A 1 556  ? 188.218 137.232 146.887 1.00 106.69 ? 574  VAL A N   1 
ATOM   4213 C CA  . VAL A 1 556  ? 187.916 138.289 145.929 1.00 95.97  ? 574  VAL A CA  1 
ATOM   4214 C C   . VAL A 1 556  ? 188.824 139.470 146.230 1.00 99.93  ? 574  VAL A C   1 
ATOM   4215 O O   . VAL A 1 556  ? 188.980 139.857 147.393 1.00 108.56 ? 574  VAL A O   1 
ATOM   4216 C CB  . VAL A 1 556  ? 186.435 138.707 145.994 1.00 97.50  ? 574  VAL A CB  1 
ATOM   4217 C CG1 . VAL A 1 556  ? 186.199 140.002 145.224 1.00 103.71 ? 574  VAL A CG1 1 
ATOM   4218 C CG2 . VAL A 1 556  ? 185.551 137.594 145.460 1.00 102.64 ? 574  VAL A CG2 1 
ATOM   4219 N N   . SER A 1 557  ? 189.422 140.035 145.188 1.00 102.08 ? 575  SER A N   1 
ATOM   4220 C CA  . SER A 1 557  ? 190.319 141.175 145.312 1.00 106.78 ? 575  SER A CA  1 
ATOM   4221 C C   . SER A 1 557  ? 189.551 142.454 145.001 1.00 105.15 ? 575  SER A C   1 
ATOM   4222 O O   . SER A 1 557  ? 188.994 142.597 143.909 1.00 113.47 ? 575  SER A O   1 
ATOM   4223 C CB  . SER A 1 557  ? 191.512 141.025 144.371 1.00 116.01 ? 575  SER A CB  1 
ATOM   4224 O OG  . SER A 1 557  ? 191.133 141.270 143.028 1.00 126.05 ? 575  SER A OG  1 
ATOM   4225 N N   . LEU A 1 558  ? 189.526 143.373 145.961 1.00 96.89  ? 576  LEU A N   1 
ATOM   4226 C CA  . LEU A 1 558  ? 188.955 144.700 145.779 1.00 93.74  ? 576  LEU A CA  1 
ATOM   4227 C C   . LEU A 1 558  ? 190.083 145.670 145.461 1.00 99.64  ? 576  LEU A C   1 
ATOM   4228 O O   . LEU A 1 558  ? 191.040 145.787 146.232 1.00 98.75  ? 576  LEU A O   1 
ATOM   4229 C CB  . LEU A 1 558  ? 188.202 145.141 147.035 1.00 88.74  ? 576  LEU A CB  1 
ATOM   4230 C CG  . LEU A 1 558  ? 187.776 146.608 147.151 1.00 89.32  ? 576  LEU A CG  1 
ATOM   4231 C CD1 . LEU A 1 558  ? 186.368 146.699 147.709 1.00 89.36  ? 576  LEU A CD1 1 
ATOM   4232 C CD2 . LEU A 1 558  ? 188.731 147.397 148.028 1.00 94.56  ? 576  LEU A CD2 1 
ATOM   4233 N N   . ARG A 1 559  ? 189.973 146.350 144.322 1.00 105.42 ? 577  ARG A N   1 
ATOM   4234 C CA  . ARG A 1 559  ? 190.971 147.306 143.864 1.00 107.72 ? 577  ARG A CA  1 
ATOM   4235 C C   . ARG A 1 559  ? 190.449 148.716 144.088 1.00 105.34 ? 577  ARG A C   1 
ATOM   4236 O O   . ARG A 1 559  ? 189.351 149.049 143.633 1.00 101.15 ? 577  ARG A O   1 
ATOM   4237 C CB  . ARG A 1 559  ? 191.290 147.101 142.383 1.00 112.12 ? 577  ARG A CB  1 
ATOM   4238 C CG  . ARG A 1 559  ? 192.140 145.881 142.090 1.00 114.05 ? 577  ARG A CG  1 
ATOM   4239 C CD  . ARG A 1 559  ? 192.354 145.710 140.597 1.00 120.04 ? 577  ARG A CD  1 
ATOM   4240 N NE  . ARG A 1 559  ? 191.289 144.926 139.981 1.00 129.25 ? 577  ARG A NE  1 
ATOM   4241 C CZ  . ARG A 1 559  ? 191.230 143.599 139.954 1.00 132.42 ? 577  ARG A CZ  1 
ATOM   4242 N NH1 . ARG A 1 559  ? 192.161 142.844 140.519 1.00 131.96 ? 577  ARG A NH1 1 
ATOM   4243 N NH2 . ARG A 1 559  ? 190.204 143.011 139.345 1.00 130.60 ? 577  ARG A NH2 1 
ATOM   4244 N N   . ILE A 1 560  ? 191.240 149.536 144.776 1.00 101.94 ? 578  ILE A N   1 
ATOM   4245 C CA  . ILE A 1 560  ? 190.930 150.944 145.000 1.00 95.60  ? 578  ILE A CA  1 
ATOM   4246 C C   . ILE A 1 560  ? 191.922 151.772 144.204 1.00 99.85  ? 578  ILE A C   1 
ATOM   4247 O O   . ILE A 1 560  ? 193.116 151.456 144.164 1.00 108.05 ? 578  ILE A O   1 
ATOM   4248 C CB  . ILE A 1 560  ? 190.963 151.334 146.494 1.00 96.68  ? 578  ILE A CB  1 
ATOM   4249 C CG1 . ILE A 1 560  ? 192.312 151.002 147.146 1.00 106.73 ? 578  ILE A CG1 1 
ATOM   4250 C CG2 . ILE A 1 560  ? 189.849 150.632 147.250 1.00 103.59 ? 578  ILE A CG2 1 
ATOM   4251 C CD1 . ILE A 1 560  ? 192.348 151.297 148.630 1.00 107.31 ? 578  ILE A CD1 1 
ATOM   4252 N N   . SER A 1 561  ? 191.419 152.816 143.550 1.00 104.47 ? 579  SER A N   1 
ATOM   4253 C CA  . SER A 1 561  ? 192.232 153.748 142.781 1.00 110.23 ? 579  SER A CA  1 
ATOM   4254 C C   . SER A 1 561  ? 191.915 155.158 143.248 1.00 110.09 ? 579  SER A C   1 
ATOM   4255 O O   . SER A 1 561  ? 190.744 155.551 143.288 1.00 110.95 ? 579  SER A O   1 
ATOM   4256 C CB  . SER A 1 561  ? 191.967 153.614 141.280 1.00 110.95 ? 579  SER A CB  1 
ATOM   4257 O OG  . SER A 1 561  ? 192.515 154.711 140.571 1.00 108.65 ? 579  SER A OG  1 
ATOM   4258 N N   . VAL A 1 562  ? 192.960 155.908 143.588 1.00 108.74 ? 580  VAL A N   1 
ATOM   4259 C CA  . VAL A 1 562  ? 192.852 157.259 144.124 1.00 103.82 ? 580  VAL A CA  1 
ATOM   4260 C C   . VAL A 1 562  ? 193.699 158.179 143.256 1.00 113.29 ? 580  VAL A C   1 
ATOM   4261 O O   . VAL A 1 562  ? 194.775 157.788 142.790 1.00 125.38 ? 580  VAL A O   1 
ATOM   4262 C CB  . VAL A 1 562  ? 193.292 157.319 145.605 1.00 102.53 ? 580  VAL A CB  1 
ATOM   4263 C CG1 . VAL A 1 562  ? 194.635 156.619 145.818 1.00 113.92 ? 580  VAL A CG1 1 
ATOM   4264 C CG2 . VAL A 1 562  ? 193.354 158.756 146.099 1.00 108.52 ? 580  VAL A CG2 1 
ATOM   4265 N N   . THR A 1 563  ? 193.206 159.398 143.034 1.00 109.94 ? 581  THR A N   1 
ATOM   4266 C CA  . THR A 1 563  ? 193.848 160.297 142.080 1.00 117.67 ? 581  THR A CA  1 
ATOM   4267 C C   . THR A 1 563  ? 195.249 160.700 142.527 1.00 122.18 ? 581  THR A C   1 
ATOM   4268 O O   . THR A 1 563  ? 196.182 160.697 141.717 1.00 130.25 ? 581  THR A O   1 
ATOM   4269 C CB  . THR A 1 563  ? 192.982 161.539 141.873 1.00 120.30 ? 581  THR A CB  1 
ATOM   4270 O OG1 . THR A 1 563  ? 191.597 161.171 141.913 1.00 118.13 ? 581  THR A OG1 1 
ATOM   4271 C CG2 . THR A 1 563  ? 193.292 162.192 140.534 1.00 123.85 ? 581  THR A CG2 1 
ATOM   4272 N N   . GLN A 1 564  ? 195.418 161.032 143.810 1.00 116.06 ? 582  GLN A N   1 
ATOM   4273 C CA  . GLN A 1 564  ? 196.646 161.603 144.346 1.00 118.06 ? 582  GLN A CA  1 
ATOM   4274 C C   . GLN A 1 564  ? 197.213 160.694 145.432 1.00 122.08 ? 582  GLN A C   1 
ATOM   4275 O O   . GLN A 1 564  ? 196.447 160.188 146.260 1.00 127.69 ? 582  GLN A O   1 
ATOM   4276 C CB  . GLN A 1 564  ? 196.369 163.003 144.918 1.00 122.56 ? 582  GLN A CB  1 
ATOM   4277 C CG  . GLN A 1 564  ? 197.413 163.526 145.910 1.00 128.54 ? 582  GLN A CG  1 
ATOM   4278 C CD  . GLN A 1 564  ? 197.427 165.043 146.035 1.00 141.26 ? 582  GLN A CD  1 
ATOM   4279 O OE1 . GLN A 1 564  ? 196.970 165.763 145.147 1.00 144.19 ? 582  GLN A OE1 1 
ATOM   4280 N NE2 . GLN A 1 564  ? 197.956 165.533 147.149 1.00 144.63 ? 582  GLN A NE2 1 
ATOM   4281 N N   . PRO A 1 565  ? 198.552 160.460 145.477 1.00 123.32 ? 583  PRO A N   1 
ATOM   4282 C CA  . PRO A 1 565  ? 199.086 159.607 146.549 1.00 127.21 ? 583  PRO A CA  1 
ATOM   4283 C C   . PRO A 1 565  ? 199.117 160.316 147.894 1.00 129.63 ? 583  PRO A C   1 
ATOM   4284 O O   . PRO A 1 565  ? 198.705 161.475 147.996 1.00 132.26 ? 583  PRO A O   1 
ATOM   4285 C CB  . PRO A 1 565  ? 200.496 159.267 146.051 1.00 125.23 ? 583  PRO A CB  1 
ATOM   4286 C CG  . PRO A 1 565  ? 200.882 160.436 145.255 1.00 123.45 ? 583  PRO A CG  1 
ATOM   4287 C CD  . PRO A 1 565  ? 199.629 160.871 144.554 1.00 123.64 ? 583  PRO A CD  1 
ATOM   4288 N N   . ASP A 1 566  ? 199.618 159.630 148.924 1.00 127.34 ? 584  ASP A N   1 
ATOM   4289 C CA  . ASP A 1 566  ? 199.653 160.155 150.292 1.00 124.90 ? 584  ASP A CA  1 
ATOM   4290 C C   . ASP A 1 566  ? 198.249 160.538 150.757 1.00 124.80 ? 584  ASP A C   1 
ATOM   4291 O O   . ASP A 1 566  ? 198.031 161.586 151.370 1.00 123.02 ? 584  ASP A O   1 
ATOM   4292 C CB  . ASP A 1 566  ? 200.626 161.335 150.407 1.00 130.20 ? 584  ASP A CB  1 
ATOM   4293 C CG  . ASP A 1 566  ? 202.070 160.888 150.489 1.00 139.56 ? 584  ASP A CG  1 
ATOM   4294 O OD1 . ASP A 1 566  ? 202.398 160.109 151.408 1.00 143.27 ? 584  ASP A OD1 1 
ATOM   4295 O OD2 . ASP A 1 566  ? 202.876 161.315 149.637 1.00 147.10 ? 584  ASP A OD2 1 
ATOM   4296 N N   . SER A 1 567  ? 197.288 159.670 150.454 1.00 120.87 ? 585  SER A N   1 
ATOM   4297 C CA  . SER A 1 567  ? 195.889 159.852 150.805 1.00 112.64 ? 585  SER A CA  1 
ATOM   4298 C C   . SER A 1 567  ? 195.457 158.758 151.770 1.00 106.99 ? 585  SER A C   1 
ATOM   4299 O O   . SER A 1 567  ? 195.970 157.636 151.727 1.00 111.51 ? 585  SER A O   1 
ATOM   4300 C CB  . SER A 1 567  ? 195.004 159.815 149.557 1.00 112.53 ? 585  SER A CB  1 
ATOM   4301 O OG  . SER A 1 567  ? 195.487 160.698 148.562 1.00 123.01 ? 585  SER A OG  1 
ATOM   4302 N N   . ILE A 1 568  ? 194.507 159.097 152.641 1.00 102.09 ? 586  ILE A N   1 
ATOM   4303 C CA  . ILE A 1 568  ? 193.934 158.160 153.603 1.00 96.63  ? 586  ILE A CA  1 
ATOM   4304 C C   . ILE A 1 568  ? 192.530 157.815 153.134 1.00 94.55  ? 586  ILE A C   1 
ATOM   4305 O O   . ILE A 1 568  ? 191.718 158.711 152.872 1.00 93.57  ? 586  ILE A O   1 
ATOM   4306 C CB  . ILE A 1 568  ? 193.935 158.722 155.039 1.00 96.45  ? 586  ILE A CB  1 
ATOM   4307 C CG1 . ILE A 1 568  ? 193.267 157.730 155.995 1.00 98.17  ? 586  ILE A CG1 1 
ATOM   4308 C CG2 . ILE A 1 568  ? 193.240 160.086 155.137 1.00 98.42  ? 586  ILE A CG2 1 
ATOM   4309 C CD1 . ILE A 1 568  ? 193.630 157.939 157.451 1.00 102.04 ? 586  ILE A CD1 1 
ATOM   4310 N N   . VAL A 1 569  ? 192.252 156.519 153.016 1.00 97.31  ? 587  VAL A N   1 
ATOM   4311 C CA  . VAL A 1 569  ? 191.025 156.017 152.414 1.00 92.09  ? 587  VAL A CA  1 
ATOM   4312 C C   . VAL A 1 569  ? 190.259 155.217 153.453 1.00 94.00  ? 587  VAL A C   1 
ATOM   4313 O O   . VAL A 1 569  ? 190.845 154.562 154.325 1.00 100.71 ? 587  VAL A O   1 
ATOM   4314 C CB  . VAL A 1 569  ? 191.324 155.160 151.165 1.00 81.97  ? 587  VAL A CB  1 
ATOM   4315 C CG1 . VAL A 1 569  ? 192.348 155.850 150.287 1.00 91.36  ? 587  VAL A CG1 1 
ATOM   4316 C CG2 . VAL A 1 569  ? 191.829 153.776 151.552 1.00 91.94  ? 587  VAL A CG2 1 
ATOM   4317 N N   . GLY A 1 570  ? 188.934 155.280 153.353 1.00 86.77  ? 588  GLY A N   1 
ATOM   4318 C CA  . GLY A 1 570  ? 188.054 154.460 154.162 1.00 86.56  ? 588  GLY A CA  1 
ATOM   4319 C C   . GLY A 1 570  ? 186.952 153.865 153.316 1.00 89.59  ? 588  GLY A C   1 
ATOM   4320 O O   . GLY A 1 570  ? 186.183 154.601 152.692 1.00 97.81  ? 588  GLY A O   1 
ATOM   4321 N N   . ILE A 1 571  ? 186.870 152.538 153.290 1.00 85.13  ? 589  ILE A N   1 
ATOM   4322 C CA  . ILE A 1 571  ? 185.946 151.797 152.439 1.00 79.03  ? 589  ILE A CA  1 
ATOM   4323 C C   . ILE A 1 571  ? 185.020 150.994 153.338 1.00 80.33  ? 589  ILE A C   1 
ATOM   4324 O O   . ILE A 1 571  ? 185.482 150.303 154.254 1.00 87.20  ? 589  ILE A O   1 
ATOM   4325 C CB  . ILE A 1 571  ? 186.696 150.875 151.458 1.00 75.81  ? 589  ILE A CB  1 
ATOM   4326 C CG1 . ILE A 1 571  ? 187.623 151.704 150.563 1.00 84.97  ? 589  ILE A CG1 1 
ATOM   4327 C CG2 . ILE A 1 571  ? 185.718 150.035 150.624 1.00 80.75  ? 589  ILE A CG2 1 
ATOM   4328 C CD1 . ILE A 1 571  ? 189.082 151.448 150.815 1.00 95.28  ? 589  ILE A CD1 1 
ATOM   4329 N N   . VAL A 1 572  ? 183.719 151.088 153.073 1.00 78.26  ? 590  VAL A N   1 
ATOM   4330 C CA  . VAL A 1 572  ? 182.702 150.303 153.760 1.00 80.04  ? 590  VAL A CA  1 
ATOM   4331 C C   . VAL A 1 572  ? 181.973 149.466 152.719 1.00 86.19  ? 590  VAL A C   1 
ATOM   4332 O O   . VAL A 1 572  ? 181.474 149.999 151.719 1.00 95.32  ? 590  VAL A O   1 
ATOM   4333 C CB  . VAL A 1 572  ? 181.722 151.189 154.558 1.00 88.44  ? 590  VAL A CB  1 
ATOM   4334 C CG1 . VAL A 1 572  ? 181.209 152.372 153.734 1.00 89.53  ? 590  VAL A CG1 1 
ATOM   4335 C CG2 . VAL A 1 572  ? 180.557 150.357 155.082 1.00 95.03  ? 590  VAL A CG2 1 
ATOM   4336 N N   . ALA A 1 573  ? 181.938 148.154 152.947 1.00 84.50  ? 591  ALA A N   1 
ATOM   4337 C CA  . ALA A 1 573  ? 181.205 147.210 152.114 1.00 84.07  ? 591  ALA A CA  1 
ATOM   4338 C C   . ALA A 1 573  ? 180.186 146.509 152.993 1.00 90.85  ? 591  ALA A C   1 
ATOM   4339 O O   . ALA A 1 573  ? 180.564 145.764 153.908 1.00 101.08 ? 591  ALA A O   1 
ATOM   4340 C CB  . ALA A 1 573  ? 182.140 146.197 151.455 1.00 84.99  ? 591  ALA A CB  1 
ATOM   4341 N N   . VAL A 1 574  ? 178.905 146.740 152.693 1.00 90.26  ? 592  VAL A N   1 
ATOM   4342 C CA  . VAL A 1 574  ? 177.785 146.394 153.560 1.00 102.90 ? 592  VAL A CA  1 
ATOM   4343 C C   . VAL A 1 574  ? 176.672 145.803 152.700 1.00 103.96 ? 592  VAL A C   1 
ATOM   4344 O O   . VAL A 1 574  ? 176.637 145.979 151.482 1.00 104.88 ? 592  VAL A O   1 
ATOM   4345 C CB  . VAL A 1 574  ? 177.297 147.631 154.356 1.00 105.82 ? 592  VAL A CB  1 
ATOM   4346 C CG1 . VAL A 1 574  ? 176.345 148.505 153.534 1.00 110.54 ? 592  VAL A CG1 1 
ATOM   4347 C CG2 . VAL A 1 574  ? 176.661 147.232 155.689 1.00 112.82 ? 592  VAL A CG2 1 
ATOM   4348 N N   . ASP A 1 575  ? 175.761 145.082 153.348 1.00 112.46 ? 593  ASP A N   1 
ATOM   4349 C CA  . ASP A 1 575  ? 174.631 144.484 152.654 1.00 116.78 ? 593  ASP A CA  1 
ATOM   4350 C C   . ASP A 1 575  ? 173.743 145.562 152.033 1.00 128.52 ? 593  ASP A C   1 
ATOM   4351 O O   . ASP A 1 575  ? 173.733 146.719 152.456 1.00 139.25 ? 593  ASP A O   1 
ATOM   4352 C CB  . ASP A 1 575  ? 173.811 143.626 153.618 1.00 132.19 ? 593  ASP A CB  1 
ATOM   4353 C CG  . ASP A 1 575  ? 172.893 142.654 152.904 1.00 138.80 ? 593  ASP A CG  1 
ATOM   4354 O OD1 . ASP A 1 575  ? 172.699 142.799 151.679 1.00 136.54 ? 593  ASP A OD1 1 
ATOM   4355 O OD2 . ASP A 1 575  ? 172.363 141.741 153.570 1.00 145.62 ? 593  ASP A OD2 1 
ATOM   4356 N N   . LYS A 1 576  ? 172.983 145.161 151.013 1.00 126.66 ? 594  LYS A N   1 
ATOM   4357 C CA  . LYS A 1 576  ? 172.137 146.097 150.283 1.00 128.27 ? 594  LYS A CA  1 
ATOM   4358 C C   . LYS A 1 576  ? 170.888 146.514 151.049 1.00 147.31 ? 594  LYS A C   1 
ATOM   4359 O O   . LYS A 1 576  ? 170.199 147.439 150.607 1.00 155.07 ? 594  LYS A O   1 
ATOM   4360 C CB  . LYS A 1 576  ? 171.718 145.499 148.939 1.00 116.99 ? 594  LYS A CB  1 
ATOM   4361 C CG  . LYS A 1 576  ? 171.618 146.525 147.821 1.00 118.68 ? 594  LYS A CG  1 
ATOM   4362 C CD  . LYS A 1 576  ? 171.385 145.878 146.466 1.00 118.87 ? 594  LYS A CD  1 
ATOM   4363 C CE  . LYS A 1 576  ? 171.736 146.833 145.337 1.00 116.45 ? 594  LYS A CE  1 
ATOM   4364 N NZ  . LYS A 1 576  ? 171.366 146.288 144.003 1.00 111.24 ? 594  LYS A NZ  1 
ATOM   4365 N N   . SER A 1 577  ? 170.574 145.868 152.175 1.00 150.74 ? 595  SER A N   1 
ATOM   4366 C CA  . SER A 1 577  ? 169.411 146.275 152.957 1.00 158.57 ? 595  SER A CA  1 
ATOM   4367 C C   . SER A 1 577  ? 169.568 147.673 153.542 1.00 167.22 ? 595  SER A C   1 
ATOM   4368 O O   . SER A 1 577  ? 168.561 148.302 153.885 1.00 175.33 ? 595  SER A O   1 
ATOM   4369 C CB  . SER A 1 577  ? 169.148 145.272 154.082 1.00 155.22 ? 595  SER A CB  1 
ATOM   4370 O OG  . SER A 1 577  ? 169.791 145.667 155.280 1.00 146.92 ? 595  SER A OG  1 
ATOM   4371 N N   . VAL A 1 578  ? 170.802 148.168 153.668 1.00 164.44 ? 596  VAL A N   1 
ATOM   4372 C CA  . VAL A 1 578  ? 171.011 149.543 154.113 1.00 174.55 ? 596  VAL A CA  1 
ATOM   4373 C C   . VAL A 1 578  ? 170.378 150.514 153.125 1.00 181.38 ? 596  VAL A C   1 
ATOM   4374 O O   . VAL A 1 578  ? 169.709 151.477 153.520 1.00 185.25 ? 596  VAL A O   1 
ATOM   4375 C CB  . VAL A 1 578  ? 172.519 149.810 154.302 1.00 173.86 ? 596  VAL A CB  1 
ATOM   4376 C CG1 . VAL A 1 578  ? 172.839 151.311 154.303 1.00 179.90 ? 596  VAL A CG1 1 
ATOM   4377 C CG2 . VAL A 1 578  ? 173.011 149.156 155.584 1.00 161.23 ? 596  VAL A CG2 1 
ATOM   4378 N N   . ASN A 1 579  ? 170.580 150.281 151.827 1.00 179.73 ? 597  ASN A N   1 
ATOM   4379 C CA  . ASN A 1 579  ? 169.940 151.124 150.824 1.00 185.09 ? 597  ASN A CA  1 
ATOM   4380 C C   . ASN A 1 579  ? 168.427 150.951 150.836 1.00 187.99 ? 597  ASN A C   1 
ATOM   4381 O O   . ASN A 1 579  ? 167.694 151.908 150.563 1.00 188.21 ? 597  ASN A O   1 
ATOM   4382 C CB  . ASN A 1 579  ? 170.500 150.808 149.438 1.00 179.95 ? 597  ASN A CB  1 
ATOM   4383 C CG  . ASN A 1 579  ? 171.956 151.207 149.294 1.00 180.28 ? 597  ASN A CG  1 
ATOM   4384 O OD1 . ASN A 1 579  ? 172.673 151.349 150.284 1.00 178.85 ? 597  ASN A OD1 1 
ATOM   4385 N ND2 . ASN A 1 579  ? 172.399 151.392 148.057 1.00 170.62 ? 597  ASN A ND2 1 
ATOM   4386 N N   . LEU A 1 580  ? 167.942 149.746 151.149 1.00 186.84 ? 598  LEU A N   1 
ATOM   4387 C CA  . LEU A 1 580  ? 166.503 149.537 151.257 1.00 186.60 ? 598  LEU A CA  1 
ATOM   4388 C C   . LEU A 1 580  ? 165.913 150.328 152.417 1.00 188.20 ? 598  LEU A C   1 
ATOM   4389 O O   . LEU A 1 580  ? 164.776 150.803 152.325 1.00 186.94 ? 598  LEU A O   1 
ATOM   4390 C CB  . LEU A 1 580  ? 166.200 148.047 151.425 1.00 182.09 ? 598  LEU A CB  1 
ATOM   4391 C CG  . LEU A 1 580  ? 166.704 147.090 150.338 1.00 181.46 ? 598  LEU A CG  1 
ATOM   4392 C CD1 . LEU A 1 580  ? 166.237 145.674 150.634 1.00 174.59 ? 598  LEU A CD1 1 
ATOM   4393 C CD2 . LEU A 1 580  ? 166.247 147.515 148.947 1.00 183.94 ? 598  LEU A CD2 1 
ATOM   4394 N N   . MET A 1 581  ? 166.664 150.473 153.512 1.00 188.89 ? 599  MET A N   1 
ATOM   4395 C CA  . MET A 1 581  ? 166.208 151.317 154.612 1.00 187.95 ? 599  MET A CA  1 
ATOM   4396 C C   . MET A 1 581  ? 166.055 152.769 154.178 1.00 191.98 ? 599  MET A C   1 
ATOM   4397 O O   . MET A 1 581  ? 165.149 153.462 154.654 1.00 191.11 ? 599  MET A O   1 
ATOM   4398 C CB  . MET A 1 581  ? 167.181 151.235 155.789 1.00 184.17 ? 599  MET A CB  1 
ATOM   4399 C CG  . MET A 1 581  ? 166.877 150.130 156.784 1.00 186.16 ? 599  MET A CG  1 
ATOM   4400 S SD  . MET A 1 581  ? 168.210 149.911 157.979 1.00 192.18 ? 599  MET A SD  1 
ATOM   4401 C CE  . MET A 1 581  ? 167.682 148.416 158.810 1.00 154.66 ? 599  MET A CE  1 
ATOM   4402 N N   . ASN A 1 582  ? 166.928 153.244 153.289 1.00 194.83 ? 600  ASN A N   1 
ATOM   4403 C CA  . ASN A 1 582  ? 166.924 154.637 152.840 1.00 196.94 ? 600  ASN A CA  1 
ATOM   4404 C C   . ASN A 1 582  ? 167.176 155.604 153.994 1.00 192.03 ? 600  ASN A C   1 
ATOM   4405 O O   . ASN A 1 582  ? 166.714 156.747 153.973 1.00 191.28 ? 600  ASN A O   1 
ATOM   4406 C CB  . ASN A 1 582  ? 165.607 154.982 152.132 1.00 200.64 ? 600  ASN A CB  1 
ATOM   4407 C CG  . ASN A 1 582  ? 165.750 156.108 151.114 1.00 201.66 ? 600  ASN A CG  1 
ATOM   4408 O OD1 . ASN A 1 582  ? 166.848 156.424 150.652 1.00 202.85 ? 600  ASN A OD1 1 
ATOM   4409 N ND2 . ASN A 1 582  ? 164.626 156.719 150.760 1.00 198.06 ? 600  ASN A ND2 1 
ATOM   4410 N N   . ALA A 1 583  ? 167.912 155.153 155.009 1.00 185.83 ? 601  ALA A N   1 
ATOM   4411 C CA  . ALA A 1 583  ? 168.266 156.004 156.142 1.00 176.32 ? 601  ALA A CA  1 
ATOM   4412 C C   . ALA A 1 583  ? 169.479 155.374 156.811 1.00 168.24 ? 601  ALA A C   1 
ATOM   4413 O O   . ALA A 1 583  ? 169.365 154.295 157.401 1.00 170.75 ? 601  ALA A O   1 
ATOM   4414 C CB  . ALA A 1 583  ? 167.101 156.137 157.114 1.00 172.54 ? 601  ALA A CB  1 
ATOM   4415 N N   . SER A 1 584  ? 170.627 156.041 156.718 1.00 157.26 ? 602  SER A N   1 
ATOM   4416 C CA  . SER A 1 584  ? 171.876 155.472 157.198 1.00 147.44 ? 602  SER A CA  1 
ATOM   4417 C C   . SER A 1 584  ? 172.818 156.593 157.608 1.00 134.43 ? 602  SER A C   1 
ATOM   4418 O O   . SER A 1 584  ? 172.632 157.756 157.240 1.00 129.82 ? 602  SER A O   1 
ATOM   4419 C CB  . SER A 1 584  ? 172.532 154.589 156.132 1.00 151.74 ? 602  SER A CB  1 
ATOM   4420 O OG  . SER A 1 584  ? 172.636 155.277 154.897 1.00 149.52 ? 602  SER A OG  1 
ATOM   4421 N N   . ASN A 1 585  ? 173.836 156.219 158.380 1.00 121.35 ? 603  ASN A N   1 
ATOM   4422 C CA  . ASN A 1 585  ? 174.837 157.149 158.880 1.00 112.44 ? 603  ASN A CA  1 
ATOM   4423 C C   . ASN A 1 585  ? 176.063 157.250 157.981 1.00 116.08 ? 603  ASN A C   1 
ATOM   4424 O O   . ASN A 1 585  ? 176.991 157.994 158.311 1.00 118.11 ? 603  ASN A O   1 
ATOM   4425 C CB  . ASN A 1 585  ? 175.271 156.729 160.287 1.00 107.85 ? 603  ASN A CB  1 
ATOM   4426 C CG  . ASN A 1 585  ? 174.210 157.010 161.331 1.00 115.94 ? 603  ASN A CG  1 
ATOM   4427 O OD1 . ASN A 1 585  ? 173.117 157.476 161.014 1.00 122.51 ? 603  ASN A OD1 1 
ATOM   4428 N ND2 . ASN A 1 585  ? 174.529 156.727 162.588 1.00 105.85 ? 603  ASN A ND2 1 
ATOM   4429 N N   . ASP A 1 586  ? 176.093 156.536 156.858 1.00 123.21 ? 604  ASP A N   1 
ATOM   4430 C CA  . ASP A 1 586  ? 177.279 156.518 156.017 1.00 120.19 ? 604  ASP A CA  1 
ATOM   4431 C C   . ASP A 1 586  ? 177.496 157.874 155.352 1.00 117.48 ? 604  ASP A C   1 
ATOM   4432 O O   . ASP A 1 586  ? 176.570 158.671 155.179 1.00 125.34 ? 604  ASP A O   1 
ATOM   4433 C CB  . ASP A 1 586  ? 177.164 155.429 154.952 1.00 121.07 ? 604  ASP A CB  1 
ATOM   4434 C CG  . ASP A 1 586  ? 176.954 154.053 155.548 1.00 128.78 ? 604  ASP A CG  1 
ATOM   4435 O OD1 . ASP A 1 586  ? 175.888 153.823 156.155 1.00 133.55 ? 604  ASP A OD1 1 
ATOM   4436 O OD2 . ASP A 1 586  ? 177.855 153.199 155.409 1.00 120.88 ? 604  ASP A OD2 1 
ATOM   4437 N N   . ILE A 1 587  ? 178.749 158.132 154.980 1.00 107.73 ? 605  ILE A N   1 
ATOM   4438 C CA  . ILE A 1 587  ? 179.118 159.362 154.280 1.00 105.52 ? 605  ILE A CA  1 
ATOM   4439 C C   . ILE A 1 587  ? 178.727 159.181 152.817 1.00 111.72 ? 605  ILE A C   1 
ATOM   4440 O O   . ILE A 1 587  ? 179.487 158.627 152.022 1.00 113.14 ? 605  ILE A O   1 
ATOM   4441 C CB  . ILE A 1 587  ? 180.605 159.690 154.432 1.00 96.60  ? 605  ILE A CB  1 
ATOM   4442 C CG1 . ILE A 1 587  ? 180.929 160.078 155.876 1.00 96.77  ? 605  ILE A CG1 1 
ATOM   4443 C CG2 . ILE A 1 587  ? 181.007 160.821 153.494 1.00 95.21  ? 605  ILE A CG2 1 
ATOM   4444 C CD1 . ILE A 1 587  ? 182.378 159.861 156.255 1.00 98.26  ? 605  ILE A CD1 1 
ATOM   4445 N N   . THR A 1 588  ? 177.538 159.653 152.464 1.00 116.10 ? 606  THR A N   1 
ATOM   4446 C CA  . THR A 1 588  ? 177.022 159.650 151.105 1.00 115.48 ? 606  THR A CA  1 
ATOM   4447 C C   . THR A 1 588  ? 177.025 161.078 150.570 1.00 115.17 ? 606  THR A C   1 
ATOM   4448 O O   . THR A 1 588  ? 177.293 162.038 151.296 1.00 113.16 ? 606  THR A O   1 
ATOM   4449 C CB  . THR A 1 588  ? 175.615 159.051 151.069 1.00 123.16 ? 606  THR A CB  1 
ATOM   4450 O OG1 . THR A 1 588  ? 174.843 159.575 152.155 1.00 128.08 ? 606  THR A OG1 1 
ATOM   4451 C CG2 . THR A 1 588  ? 175.676 157.537 151.185 1.00 119.91 ? 606  THR A CG2 1 
ATOM   4452 N N   . MET A 1 589  ? 176.727 161.212 149.277 1.00 119.98 ? 607  MET A N   1 
ATOM   4453 C CA  . MET A 1 589  ? 176.596 162.542 148.696 1.00 121.74 ? 607  MET A CA  1 
ATOM   4454 C C   . MET A 1 589  ? 175.448 163.313 149.331 1.00 124.95 ? 607  MET A C   1 
ATOM   4455 O O   . MET A 1 589  ? 175.541 164.534 149.503 1.00 129.22 ? 607  MET A O   1 
ATOM   4456 C CB  . MET A 1 589  ? 176.390 162.433 147.184 1.00 120.80 ? 607  MET A CB  1 
ATOM   4457 C CG  . MET A 1 589  ? 176.195 163.759 146.445 1.00 129.62 ? 607  MET A CG  1 
ATOM   4458 S SD  . MET A 1 589  ? 177.278 165.111 146.948 1.00 142.51 ? 607  MET A SD  1 
ATOM   4459 C CE  . MET A 1 589  ? 178.815 164.612 146.180 1.00 128.49 ? 607  MET A CE  1 
ATOM   4460 N N   . GLU A 1 590  ? 174.364 162.620 149.687 1.00 121.58 ? 608  GLU A N   1 
ATOM   4461 C CA  . GLU A 1 590  ? 173.233 163.286 150.322 1.00 125.18 ? 608  GLU A CA  1 
ATOM   4462 C C   . GLU A 1 590  ? 173.621 163.869 151.674 1.00 129.10 ? 608  GLU A C   1 
ATOM   4463 O O   . GLU A 1 590  ? 173.179 164.966 152.028 1.00 137.25 ? 608  GLU A O   1 
ATOM   4464 C CB  . GLU A 1 590  ? 172.068 162.308 150.477 1.00 134.25 ? 608  GLU A CB  1 
ATOM   4465 C CG  . GLU A 1 590  ? 170.697 162.970 150.568 1.00 156.61 ? 608  GLU A CG  1 
ATOM   4466 C CD  . GLU A 1 590  ? 170.356 163.412 151.979 1.00 161.64 ? 608  GLU A CD  1 
ATOM   4467 O OE1 . GLU A 1 590  ? 170.129 162.535 152.839 1.00 161.03 ? 608  GLU A OE1 1 
ATOM   4468 O OE2 . GLU A 1 590  ? 170.315 164.636 152.228 1.00 156.74 ? 608  GLU A OE2 1 
ATOM   4469 N N   . ASN A 1 591  ? 174.435 163.149 152.449 1.00 121.10 ? 609  ASN A N   1 
ATOM   4470 C CA  . ASN A 1 591  ? 174.867 163.674 153.740 1.00 123.71 ? 609  ASN A CA  1 
ATOM   4471 C C   . ASN A 1 591  ? 175.735 164.914 153.568 1.00 124.36 ? 609  ASN A C   1 
ATOM   4472 O O   . ASN A 1 591  ? 175.618 165.872 154.339 1.00 129.10 ? 609  ASN A O   1 
ATOM   4473 C CB  . ASN A 1 591  ? 175.619 162.598 154.520 1.00 117.72 ? 609  ASN A CB  1 
ATOM   4474 C CG  . ASN A 1 591  ? 174.693 161.554 155.112 1.00 120.36 ? 609  ASN A CG  1 
ATOM   4475 O OD1 . ASN A 1 591  ? 173.488 161.562 154.863 1.00 121.13 ? 609  ASN A OD1 1 
ATOM   4476 N ND2 . ASN A 1 591  ? 175.254 160.649 155.904 1.00 120.52 ? 609  ASN A ND2 1 
ATOM   4477 N N   . VAL A 1 592  ? 176.611 164.915 152.562 1.00 117.45 ? 610  VAL A N   1 
ATOM   4478 C CA  . VAL A 1 592  ? 177.433 166.092 152.303 1.00 117.27 ? 610  VAL A CA  1 
ATOM   4479 C C   . VAL A 1 592  ? 176.559 167.266 151.879 1.00 123.25 ? 610  VAL A C   1 
ATOM   4480 O O   . VAL A 1 592  ? 176.791 168.410 152.289 1.00 126.48 ? 610  VAL A O   1 
ATOM   4481 C CB  . VAL A 1 592  ? 178.507 165.772 151.248 1.00 113.94 ? 610  VAL A CB  1 
ATOM   4482 C CG1 . VAL A 1 592  ? 179.252 167.037 150.845 1.00 119.23 ? 610  VAL A CG1 1 
ATOM   4483 C CG2 . VAL A 1 592  ? 179.476 164.722 151.775 1.00 109.17 ? 610  VAL A CG2 1 
ATOM   4484 N N   . VAL A 1 593  ? 175.547 167.007 151.049 1.00 121.62 ? 611  VAL A N   1 
ATOM   4485 C CA  . VAL A 1 593  ? 174.637 168.071 150.637 1.00 120.36 ? 611  VAL A CA  1 
ATOM   4486 C C   . VAL A 1 593  ? 173.874 168.612 151.841 1.00 129.25 ? 611  VAL A C   1 
ATOM   4487 O O   . VAL A 1 593  ? 173.636 169.820 151.950 1.00 136.57 ? 611  VAL A O   1 
ATOM   4488 C CB  . VAL A 1 593  ? 173.686 167.557 149.539 1.00 122.49 ? 611  VAL A CB  1 
ATOM   4489 C CG1 . VAL A 1 593  ? 172.513 168.513 149.327 1.00 127.58 ? 611  VAL A CG1 1 
ATOM   4490 C CG2 . VAL A 1 593  ? 174.444 167.358 148.237 1.00 128.57 ? 611  VAL A CG2 1 
ATOM   4491 N N   . HIS A 1 594  ? 173.465 167.728 152.752 1.00 129.12 ? 612  HIS A N   1 
ATOM   4492 C CA  . HIS A 1 594  ? 172.765 168.171 153.952 1.00 131.37 ? 612  HIS A CA  1 
ATOM   4493 C C   . HIS A 1 594  ? 173.673 169.015 154.837 1.00 128.95 ? 612  HIS A C   1 
ATOM   4494 O O   . HIS A 1 594  ? 173.236 170.023 155.403 1.00 132.51 ? 612  HIS A O   1 
ATOM   4495 C CB  . HIS A 1 594  ? 172.237 166.963 154.722 1.00 134.63 ? 612  HIS A CB  1 
ATOM   4496 C CG  . HIS A 1 594  ? 171.665 167.306 156.060 1.00 148.24 ? 612  HIS A CG  1 
ATOM   4497 N ND1 . HIS A 1 594  ? 170.529 168.073 156.209 1.00 156.97 ? 612  HIS A ND1 1 
ATOM   4498 C CD2 . HIS A 1 594  ? 172.072 166.989 157.312 1.00 150.23 ? 612  HIS A CD2 1 
ATOM   4499 C CE1 . HIS A 1 594  ? 170.261 168.212 157.495 1.00 159.13 ? 612  HIS A CE1 1 
ATOM   4500 N NE2 . HIS A 1 594  ? 171.182 167.564 158.186 1.00 153.52 ? 612  HIS A NE2 1 
ATOM   4501 N N   . GLU A 1 595  ? 174.941 168.625 154.965 1.00 122.88 ? 613  GLU A N   1 
ATOM   4502 C CA  . GLU A 1 595  ? 175.885 169.443 155.720 1.00 125.19 ? 613  GLU A CA  1 
ATOM   4503 C C   . GLU A 1 595  ? 176.066 170.809 155.070 1.00 126.39 ? 613  GLU A C   1 
ATOM   4504 O O   . GLU A 1 595  ? 176.122 171.834 155.761 1.00 133.10 ? 613  GLU A O   1 
ATOM   4505 C CB  . GLU A 1 595  ? 177.227 168.724 155.833 1.00 125.38 ? 613  GLU A CB  1 
ATOM   4506 C CG  . GLU A 1 595  ? 178.047 169.133 157.056 1.00 124.76 ? 613  GLU A CG  1 
ATOM   4507 C CD  . GLU A 1 595  ? 177.812 168.257 158.281 1.00 129.92 ? 613  GLU A CD  1 
ATOM   4508 O OE1 . GLU A 1 595  ? 176.979 167.327 158.231 1.00 138.75 ? 613  GLU A OE1 1 
ATOM   4509 O OE2 . GLU A 1 595  ? 178.474 168.504 159.311 1.00 126.39 ? 613  GLU A OE2 1 
ATOM   4510 N N   . LEU A 1 596  ? 176.147 170.846 153.739 1.00 122.57 ? 614  LEU A N   1 
ATOM   4511 C CA  . LEU A 1 596  ? 176.332 172.120 153.053 1.00 122.34 ? 614  LEU A CA  1 
ATOM   4512 C C   . LEU A 1 596  ? 175.102 173.010 153.172 1.00 129.57 ? 614  LEU A C   1 
ATOM   4513 O O   . LEU A 1 596  ? 175.234 174.235 153.251 1.00 133.38 ? 614  LEU A O   1 
ATOM   4514 C CB  . LEU A 1 596  ? 176.672 171.892 151.579 1.00 118.78 ? 614  LEU A CB  1 
ATOM   4515 C CG  . LEU A 1 596  ? 178.157 171.947 151.210 1.00 117.35 ? 614  LEU A CG  1 
ATOM   4516 C CD1 . LEU A 1 596  ? 178.673 173.378 151.208 1.00 115.60 ? 614  LEU A CD1 1 
ATOM   4517 C CD2 . LEU A 1 596  ? 178.996 171.082 152.134 1.00 120.03 ? 614  LEU A CD2 1 
ATOM   4518 N N   . GLU A 1 597  ? 173.902 172.431 153.160 1.00 129.48 ? 615  GLU A N   1 
ATOM   4519 C CA  . GLU A 1 597  ? 172.709 173.239 153.375 1.00 126.92 ? 615  GLU A CA  1 
ATOM   4520 C C   . GLU A 1 597  ? 172.588 173.682 154.826 1.00 127.63 ? 615  GLU A C   1 
ATOM   4521 O O   . GLU A 1 597  ? 172.000 174.735 155.094 1.00 133.37 ? 615  GLU A O   1 
ATOM   4522 C CB  . GLU A 1 597  ? 171.455 172.476 152.921 1.00 134.56 ? 615  GLU A CB  1 
ATOM   4523 C CG  . GLU A 1 597  ? 170.673 171.734 154.005 1.00 146.70 ? 615  GLU A CG  1 
ATOM   4524 C CD  . GLU A 1 597  ? 169.743 170.683 153.430 1.00 157.35 ? 615  GLU A CD  1 
ATOM   4525 O OE1 . GLU A 1 597  ? 169.440 170.749 152.220 1.00 164.02 ? 615  GLU A OE1 1 
ATOM   4526 O OE2 . GLU A 1 597  ? 169.315 169.788 154.189 1.00 160.44 ? 615  GLU A OE2 1 
ATOM   4527 N N   . LEU A 1 598  ? 173.138 172.905 155.763 1.00 125.02 ? 616  LEU A N   1 
ATOM   4528 C CA  . LEU A 1 598  ? 173.236 173.363 157.143 1.00 124.02 ? 616  LEU A CA  1 
ATOM   4529 C C   . LEU A 1 598  ? 174.232 174.507 157.279 1.00 122.59 ? 616  LEU A C   1 
ATOM   4530 O O   . LEU A 1 598  ? 174.090 175.346 158.174 1.00 119.78 ? 616  LEU A O   1 
ATOM   4531 C CB  . LEU A 1 598  ? 173.636 172.197 158.047 1.00 124.36 ? 616  LEU A CB  1 
ATOM   4532 C CG  . LEU A 1 598  ? 173.667 172.418 159.562 1.00 127.87 ? 616  LEU A CG  1 
ATOM   4533 C CD1 . LEU A 1 598  ? 172.349 172.961 160.093 1.00 137.23 ? 616  LEU A CD1 1 
ATOM   4534 C CD2 . LEU A 1 598  ? 174.022 171.117 160.264 1.00 124.22 ? 616  LEU A CD2 1 
ATOM   4535 N N   . TYR A 1 599  ? 175.248 174.550 156.412 1.00 127.27 ? 617  TYR A N   1 
ATOM   4536 C CA  . TYR A 1 599  ? 176.137 175.710 156.378 1.00 124.37 ? 617  TYR A CA  1 
ATOM   4537 C C   . TYR A 1 599  ? 175.379 176.987 156.037 1.00 126.23 ? 617  TYR A C   1 
ATOM   4538 O O   . TYR A 1 599  ? 175.733 178.065 156.528 1.00 126.27 ? 617  TYR A O   1 
ATOM   4539 C CB  . TYR A 1 599  ? 177.263 175.503 155.361 1.00 122.71 ? 617  TYR A CB  1 
ATOM   4540 C CG  . TYR A 1 599  ? 178.620 175.230 155.959 1.00 123.14 ? 617  TYR A CG  1 
ATOM   4541 C CD1 . TYR A 1 599  ? 179.465 176.270 156.309 1.00 122.55 ? 617  TYR A CD1 1 
ATOM   4542 C CD2 . TYR A 1 599  ? 179.064 173.931 156.152 1.00 122.47 ? 617  TYR A CD2 1 
ATOM   4543 C CE1 . TYR A 1 599  ? 180.710 176.025 156.845 1.00 121.46 ? 617  TYR A CE1 1 
ATOM   4544 C CE2 . TYR A 1 599  ? 180.306 173.677 156.687 1.00 120.98 ? 617  TYR A CE2 1 
ATOM   4545 C CZ  . TYR A 1 599  ? 181.125 174.727 157.032 1.00 121.00 ? 617  TYR A CZ  1 
ATOM   4546 O OH  . TYR A 1 599  ? 182.367 174.480 157.567 1.00 124.68 ? 617  TYR A OH  1 
ATOM   4547 N N   . ASN A 1 600  ? 174.343 176.888 155.209 1.00 132.79 ? 618  ASN A N   1 
ATOM   4548 C CA  . ASN A 1 600  ? 173.613 178.068 154.770 1.00 138.09 ? 618  ASN A CA  1 
ATOM   4549 C C   . ASN A 1 600  ? 172.801 178.654 155.921 1.00 146.80 ? 618  ASN A C   1 
ATOM   4550 O O   . ASN A 1 600  ? 172.634 178.039 156.978 1.00 151.82 ? 618  ASN A O   1 
ATOM   4551 C CB  . ASN A 1 600  ? 172.678 177.727 153.599 1.00 138.01 ? 618  ASN A CB  1 
ATOM   4552 C CG  . ASN A 1 600  ? 172.882 178.619 152.371 1.00 140.12 ? 618  ASN A CG  1 
ATOM   4553 O OD1 . ASN A 1 600  ? 173.886 179.320 152.229 1.00 138.46 ? 618  ASN A OD1 1 
ATOM   4554 N ND2 . ASN A 1 600  ? 171.910 178.584 151.468 1.00 141.39 ? 618  ASN A ND2 1 
ATOM   4555 N N   . THR A 1 601  ? 172.293 179.866 155.699 1.00 148.69 ? 619  THR A N   1 
ATOM   4556 C CA  . THR A 1 601  ? 171.558 180.608 156.713 1.00 156.97 ? 619  THR A CA  1 
ATOM   4557 C C   . THR A 1 601  ? 170.421 181.376 156.056 1.00 163.03 ? 619  THR A C   1 
ATOM   4558 O O   . THR A 1 601  ? 170.449 181.665 154.857 1.00 158.20 ? 619  THR A O   1 
ATOM   4559 C CB  . THR A 1 601  ? 172.467 181.582 157.481 1.00 158.55 ? 619  THR A CB  1 
ATOM   4560 O OG1 . THR A 1 601  ? 171.710 182.234 158.507 1.00 155.38 ? 619  THR A OG1 1 
ATOM   4561 C CG2 . THR A 1 601  ? 173.061 182.646 156.548 1.00 156.44 ? 619  THR A CG2 1 
ATOM   4562 N N   . GLY A 1 602  ? 169.415 181.710 156.866 1.00 167.91 ? 620  GLY A N   1 
ATOM   4563 C CA  . GLY A 1 602  ? 168.293 182.477 156.373 1.00 175.12 ? 620  GLY A CA  1 
ATOM   4564 C C   . GLY A 1 602  ? 168.630 183.944 156.176 1.00 182.92 ? 620  GLY A C   1 
ATOM   4565 O O   . GLY A 1 602  ? 169.575 184.481 156.751 1.00 182.96 ? 620  GLY A O   1 
ATOM   4566 N N   . TYR A 1 603  ? 167.829 184.598 155.341 1.00 189.84 ? 621  TYR A N   1 
ATOM   4567 C CA  . TYR A 1 603  ? 168.023 186.004 155.024 1.00 198.72 ? 621  TYR A CA  1 
ATOM   4568 C C   . TYR A 1 603  ? 167.417 186.891 156.108 1.00 207.86 ? 621  TYR A C   1 
ATOM   4569 O O   . TYR A 1 603  ? 166.514 186.487 156.845 1.00 204.22 ? 621  TYR A O   1 
ATOM   4570 C CB  . TYR A 1 603  ? 167.414 186.338 153.660 1.00 198.65 ? 621  TYR A CB  1 
ATOM   4571 C CG  . TYR A 1 603  ? 165.919 186.575 153.675 1.00 206.05 ? 621  TYR A CG  1 
ATOM   4572 C CD1 . TYR A 1 603  ? 165.031 185.540 153.938 1.00 204.41 ? 621  TYR A CD1 1 
ATOM   4573 C CD2 . TYR A 1 603  ? 165.396 187.833 153.411 1.00 207.33 ? 621  TYR A CD2 1 
ATOM   4574 C CE1 . TYR A 1 603  ? 163.666 185.753 153.947 1.00 201.37 ? 621  TYR A CE1 1 
ATOM   4575 C CE2 . TYR A 1 603  ? 164.032 188.056 153.416 1.00 204.82 ? 621  TYR A CE2 1 
ATOM   4576 C CZ  . TYR A 1 603  ? 163.172 187.013 153.685 1.00 198.82 ? 621  TYR A CZ  1 
ATOM   4577 O OH  . TYR A 1 603  ? 161.813 187.230 153.691 1.00 180.18 ? 621  TYR A OH  1 
ATOM   4578 N N   . TYR A 1 604  ? 167.931 188.117 156.188 1.00 217.02 ? 622  TYR A N   1 
ATOM   4579 C CA  . TYR A 1 604  ? 167.582 189.076 157.228 1.00 230.99 ? 622  TYR A CA  1 
ATOM   4580 C C   . TYR A 1 604  ? 166.781 190.229 156.638 1.00 234.09 ? 622  TYR A C   1 
ATOM   4581 O O   . TYR A 1 604  ? 167.095 190.723 155.550 1.00 229.28 ? 622  TYR A O   1 
ATOM   4582 C CB  . TYR A 1 604  ? 168.845 189.617 157.906 1.00 234.87 ? 622  TYR A CB  1 
ATOM   4583 C CG  . TYR A 1 604  ? 168.583 190.675 158.953 1.00 240.12 ? 622  TYR A CG  1 
ATOM   4584 C CD1 . TYR A 1 604  ? 167.816 190.397 160.076 1.00 240.87 ? 622  TYR A CD1 1 
ATOM   4585 C CD2 . TYR A 1 604  ? 169.105 191.955 158.817 1.00 239.89 ? 622  TYR A CD2 1 
ATOM   4586 C CE1 . TYR A 1 604  ? 167.576 191.363 161.035 1.00 241.58 ? 622  TYR A CE1 1 
ATOM   4587 C CE2 . TYR A 1 604  ? 168.871 192.927 159.770 1.00 239.75 ? 622  TYR A CE2 1 
ATOM   4588 C CZ  . TYR A 1 604  ? 168.106 192.626 160.876 1.00 240.54 ? 622  TYR A CZ  1 
ATOM   4589 O OH  . TYR A 1 604  ? 167.870 193.592 161.828 1.00 236.09 ? 622  TYR A OH  1 
ATOM   4590 N N   . LEU A 1 605  ? 165.748 190.652 157.365 1.00 240.36 ? 623  LEU A N   1 
ATOM   4591 C CA  . LEU A 1 605  ? 164.909 191.774 156.962 1.00 240.79 ? 623  LEU A CA  1 
ATOM   4592 C C   . LEU A 1 605  ? 165.456 193.074 157.534 1.00 242.56 ? 623  LEU A C   1 
ATOM   4593 O O   . LEU A 1 605  ? 165.910 193.118 158.682 1.00 245.40 ? 623  LEU A O   1 
ATOM   4594 C CB  . LEU A 1 605  ? 163.469 191.570 157.436 1.00 236.31 ? 623  LEU A CB  1 
ATOM   4595 C CG  . LEU A 1 605  ? 162.689 190.386 156.857 1.00 225.53 ? 623  LEU A CG  1 
ATOM   4596 C CD1 . LEU A 1 605  ? 161.320 190.292 157.511 1.00 214.64 ? 623  LEU A CD1 1 
ATOM   4597 C CD2 . LEU A 1 605  ? 162.542 190.506 155.347 1.00 219.67 ? 623  LEU A CD2 1 
ATOM   4598 N N   . GLY A 1 606  ? 165.410 194.129 156.719 1.00 242.13 ? 624  GLY A N   1 
ATOM   4599 C CA  . GLY A 1 606  ? 165.859 195.451 157.116 1.00 242.53 ? 624  GLY A CA  1 
ATOM   4600 C C   . GLY A 1 606  ? 164.806 196.524 156.922 1.00 246.89 ? 624  GLY A C   1 
ATOM   4601 O O   . GLY A 1 606  ? 163.708 196.432 157.480 1.00 246.23 ? 624  GLY A O   1 
ATOM   4602 N N   . MET A 1 607  ? 165.133 197.544 156.125 1.00 248.06 ? 625  MET A N   1 
ATOM   4603 C CA  . MET A 1 607  ? 164.308 198.738 155.972 1.00 247.43 ? 625  MET A CA  1 
ATOM   4604 C C   . MET A 1 607  ? 163.418 198.706 154.725 1.00 247.84 ? 625  MET A C   1 
ATOM   4605 O O   . MET A 1 607  ? 162.760 199.704 154.420 1.00 246.33 ? 625  MET A O   1 
ATOM   4606 C CB  . MET A 1 607  ? 165.218 199.981 156.030 1.00 242.91 ? 625  MET A CB  1 
ATOM   4607 C CG  . MET A 1 607  ? 166.320 200.131 154.963 1.00 240.60 ? 625  MET A CG  1 
ATOM   4608 S SD  . MET A 1 607  ? 165.866 200.387 153.243 1.00 244.73 ? 625  MET A SD  1 
ATOM   4609 C CE  . MET A 1 607  ? 164.899 201.890 153.393 1.00 237.71 ? 625  MET A CE  1 
ATOM   4610 N N   . PHE A 1 608  ? 163.348 197.570 154.029 1.00 246.32 ? 626  PHE A N   1 
ATOM   4611 C CA  . PHE A 1 608  ? 162.255 197.135 153.164 1.00 242.43 ? 626  PHE A CA  1 
ATOM   4612 C C   . PHE A 1 608  ? 162.275 197.784 151.768 1.00 240.30 ? 626  PHE A C   1 
ATOM   4613 O O   . PHE A 1 608  ? 161.528 197.337 150.895 1.00 238.10 ? 626  PHE A O   1 
ATOM   4614 C CB  . PHE A 1 608  ? 160.874 197.385 153.812 1.00 238.44 ? 626  PHE A CB  1 
ATOM   4615 C CG  . PHE A 1 608  ? 159.725 196.717 153.108 1.00 233.17 ? 626  PHE A CG  1 
ATOM   4616 C CD1 . PHE A 1 608  ? 159.618 195.339 153.091 1.00 229.99 ? 626  PHE A CD1 1 
ATOM   4617 C CD2 . PHE A 1 608  ? 158.756 197.469 152.463 1.00 228.30 ? 626  PHE A CD2 1 
ATOM   4618 C CE1 . PHE A 1 608  ? 158.570 194.719 152.445 1.00 225.86 ? 626  PHE A CE1 1 
ATOM   4619 C CE2 . PHE A 1 608  ? 157.703 196.855 151.815 1.00 222.95 ? 626  PHE A CE2 1 
ATOM   4620 C CZ  . PHE A 1 608  ? 157.610 195.477 151.806 1.00 223.16 ? 626  PHE A CZ  1 
ATOM   4621 N N   . MET A 1 609  ? 163.127 198.770 151.501 1.00 239.02 ? 627  MET A N   1 
ATOM   4622 C CA  . MET A 1 609  ? 163.100 199.410 150.192 1.00 231.83 ? 627  MET A CA  1 
ATOM   4623 C C   . MET A 1 609  ? 163.619 198.440 149.129 1.00 228.46 ? 627  MET A C   1 
ATOM   4624 O O   . MET A 1 609  ? 164.457 197.575 149.403 1.00 228.55 ? 627  MET A O   1 
ATOM   4625 C CB  . MET A 1 609  ? 163.920 200.700 150.220 1.00 227.27 ? 627  MET A CB  1 
ATOM   4626 C CG  . MET A 1 609  ? 164.140 201.365 148.873 1.00 219.24 ? 627  MET A CG  1 
ATOM   4627 S SD  . MET A 1 609  ? 165.687 200.910 148.091 1.00 217.12 ? 627  MET A SD  1 
ATOM   4628 C CE  . MET A 1 609  ? 166.670 202.366 148.433 1.00 200.62 ? 627  MET A CE  1 
ATOM   4629 N N   . ASN A 1 610  ? 163.085 198.578 147.909 1.00 227.41 ? 628  ASN A N   1 
ATOM   4630 C CA  . ASN A 1 610  ? 163.279 197.558 146.873 1.00 222.87 ? 628  ASN A CA  1 
ATOM   4631 C C   . ASN A 1 610  ? 164.747 197.363 146.506 1.00 219.01 ? 628  ASN A C   1 
ATOM   4632 O O   . ASN A 1 610  ? 165.218 196.223 146.427 1.00 210.51 ? 628  ASN A O   1 
ATOM   4633 C CB  . ASN A 1 610  ? 162.476 197.904 145.614 1.00 217.00 ? 628  ASN A CB  1 
ATOM   4634 C CG  . ASN A 1 610  ? 162.695 199.335 145.138 1.00 216.00 ? 628  ASN A CG  1 
ATOM   4635 O OD1 . ASN A 1 610  ? 163.823 199.747 144.866 1.00 218.37 ? 628  ASN A OD1 1 
ATOM   4636 N ND2 . ASN A 1 610  ? 161.608 200.090 145.019 1.00 209.48 ? 628  ASN A ND2 1 
ATOM   4637 N N   . SER A 1 611  ? 165.485 198.449 146.253 1.00 220.56 ? 629  SER A N   1 
ATOM   4638 C CA  . SER A 1 611  ? 166.876 198.288 145.839 1.00 213.99 ? 629  SER A CA  1 
ATOM   4639 C C   . SER A 1 611  ? 167.725 197.714 146.964 1.00 206.32 ? 629  SER A C   1 
ATOM   4640 O O   . SER A 1 611  ? 168.726 197.038 146.700 1.00 193.45 ? 629  SER A O   1 
ATOM   4641 C CB  . SER A 1 611  ? 167.457 199.621 145.364 1.00 213.06 ? 629  SER A CB  1 
ATOM   4642 O OG  . SER A 1 611  ? 166.590 200.249 144.437 1.00 213.46 ? 629  SER A OG  1 
ATOM   4643 N N   . PHE A 1 612  ? 167.360 197.992 148.216 1.00 210.78 ? 630  PHE A N   1 
ATOM   4644 C CA  . PHE A 1 612  ? 167.989 197.322 149.347 1.00 208.21 ? 630  PHE A CA  1 
ATOM   4645 C C   . PHE A 1 612  ? 167.409 195.931 149.585 1.00 208.15 ? 630  PHE A C   1 
ATOM   4646 O O   . PHE A 1 612  ? 168.125 195.041 150.053 1.00 205.45 ? 630  PHE A O   1 
ATOM   4647 C CB  . PHE A 1 612  ? 167.841 198.176 150.606 1.00 214.47 ? 630  PHE A CB  1 
ATOM   4648 C CG  . PHE A 1 612  ? 168.331 197.504 151.851 1.00 217.13 ? 630  PHE A CG  1 
ATOM   4649 C CD1 . PHE A 1 612  ? 169.655 197.117 151.975 1.00 211.84 ? 630  PHE A CD1 1 
ATOM   4650 C CD2 . PHE A 1 612  ? 167.466 197.258 152.899 1.00 221.93 ? 630  PHE A CD2 1 
ATOM   4651 C CE1 . PHE A 1 612  ? 170.103 196.495 153.123 1.00 206.14 ? 630  PHE A CE1 1 
ATOM   4652 C CE2 . PHE A 1 612  ? 167.908 196.642 154.045 1.00 222.12 ? 630  PHE A CE2 1 
ATOM   4653 C CZ  . PHE A 1 612  ? 169.227 196.257 154.161 1.00 215.99 ? 630  PHE A CZ  1 
ATOM   4654 N N   . ALA A 1 613  ? 166.126 195.725 149.275 1.00 213.23 ? 631  ALA A N   1 
ATOM   4655 C CA  . ALA A 1 613  ? 165.502 194.427 149.522 1.00 210.49 ? 631  ALA A CA  1 
ATOM   4656 C C   . ALA A 1 613  ? 166.063 193.354 148.596 1.00 199.97 ? 631  ALA A C   1 
ATOM   4657 O O   . ALA A 1 613  ? 166.259 192.204 149.010 1.00 199.32 ? 631  ALA A O   1 
ATOM   4658 C CB  . ALA A 1 613  ? 163.988 194.540 149.354 1.00 213.40 ? 631  ALA A CB  1 
ATOM   4659 N N   . VAL A 1 614  ? 166.313 193.706 147.335 1.00 194.03 ? 632  VAL A N   1 
ATOM   4660 C CA  . VAL A 1 614  ? 166.878 192.740 146.398 1.00 185.12 ? 632  VAL A CA  1 
ATOM   4661 C C   . VAL A 1 614  ? 168.275 192.323 146.841 1.00 181.39 ? 632  VAL A C   1 
ATOM   4662 O O   . VAL A 1 614  ? 168.691 191.182 146.609 1.00 176.81 ? 632  VAL A O   1 
ATOM   4663 C CB  . VAL A 1 614  ? 166.871 193.316 144.966 1.00 182.40 ? 632  VAL A CB  1 
ATOM   4664 C CG1 . VAL A 1 614  ? 167.764 194.544 144.845 1.00 181.64 ? 632  VAL A CG1 1 
ATOM   4665 C CG2 . VAL A 1 614  ? 167.282 192.260 143.953 1.00 160.67 ? 632  VAL A CG2 1 
ATOM   4666 N N   . PHE A 1 615  ? 169.017 193.222 147.490 1.00 179.92 ? 633  PHE A N   1 
ATOM   4667 C CA  . PHE A 1 615  ? 170.304 192.848 148.066 1.00 171.94 ? 633  PHE A CA  1 
ATOM   4668 C C   . PHE A 1 615  ? 170.130 192.008 149.326 1.00 175.62 ? 633  PHE A C   1 
ATOM   4669 O O   . PHE A 1 615  ? 170.867 191.038 149.536 1.00 170.99 ? 633  PHE A O   1 
ATOM   4670 C CB  . PHE A 1 615  ? 171.125 194.098 148.379 1.00 165.45 ? 633  PHE A CB  1 
ATOM   4671 C CG  . PHE A 1 615  ? 171.923 194.603 147.215 1.00 153.75 ? 633  PHE A CG  1 
ATOM   4672 C CD1 . PHE A 1 615  ? 171.294 195.031 146.061 1.00 152.06 ? 633  PHE A CD1 1 
ATOM   4673 C CD2 . PHE A 1 615  ? 173.303 194.647 147.274 1.00 149.47 ? 633  PHE A CD2 1 
ATOM   4674 C CE1 . PHE A 1 615  ? 172.027 195.496 144.989 1.00 146.39 ? 633  PHE A CE1 1 
ATOM   4675 C CE2 . PHE A 1 615  ? 174.040 195.111 146.205 1.00 143.39 ? 633  PHE A CE2 1 
ATOM   4676 C CZ  . PHE A 1 615  ? 173.401 195.535 145.061 1.00 139.35 ? 633  PHE A CZ  1 
ATOM   4677 N N   . GLN A 1 616  ? 169.156 192.356 150.168 1.00 184.39 ? 634  GLN A N   1 
ATOM   4678 C CA  . GLN A 1 616  ? 168.915 191.629 151.410 1.00 188.50 ? 634  GLN A CA  1 
ATOM   4679 C C   . GLN A 1 616  ? 168.249 190.277 151.186 1.00 189.00 ? 634  GLN A C   1 
ATOM   4680 O O   . GLN A 1 616  ? 168.042 189.550 152.165 1.00 194.62 ? 634  GLN A O   1 
ATOM   4681 C CB  . GLN A 1 616  ? 168.064 192.487 152.365 1.00 202.19 ? 634  GLN A CB  1 
ATOM   4682 C CG  . GLN A 1 616  ? 166.555 192.182 152.408 1.00 209.72 ? 634  GLN A CG  1 
ATOM   4683 C CD  . GLN A 1 616  ? 165.772 193.228 153.176 1.00 218.53 ? 634  GLN A CD  1 
ATOM   4684 O OE1 . GLN A 1 616  ? 166.345 194.036 153.905 1.00 223.02 ? 634  GLN A OE1 1 
ATOM   4685 N NE2 . GLN A 1 616  ? 164.453 193.215 153.018 1.00 221.92 ? 634  GLN A NE2 1 
ATOM   4686 N N   . GLU A 1 617  ? 167.877 189.949 149.941 1.00 185.43 ? 635  GLU A N   1 
ATOM   4687 C CA  . GLU A 1 617  ? 167.263 188.656 149.643 1.00 187.29 ? 635  GLU A CA  1 
ATOM   4688 C C   . GLU A 1 617  ? 168.085 187.481 150.159 1.00 185.70 ? 635  GLU A C   1 
ATOM   4689 O O   . GLU A 1 617  ? 167.515 186.466 150.575 1.00 189.07 ? 635  GLU A O   1 
ATOM   4690 C CB  . GLU A 1 617  ? 167.061 188.511 148.134 1.00 182.03 ? 635  GLU A CB  1 
ATOM   4691 C CG  . GLU A 1 617  ? 165.766 189.124 147.619 1.00 189.93 ? 635  GLU A CG  1 
ATOM   4692 C CD  . GLU A 1 617  ? 164.575 188.180 147.704 1.00 196.66 ? 635  GLU A CD  1 
ATOM   4693 O OE1 . GLU A 1 617  ? 164.705 187.081 148.283 1.00 194.21 ? 635  GLU A OE1 1 
ATOM   4694 O OE2 . GLU A 1 617  ? 163.498 188.545 147.186 1.00 200.77 ? 635  GLU A OE2 1 
ATOM   4695 N N   . CYS A 1 618  ? 169.412 187.587 150.128 1.00 179.77 ? 636  CYS A N   1 
ATOM   4696 C CA  . CYS A 1 618  ? 170.292 186.625 150.789 1.00 178.10 ? 636  CYS A CA  1 
ATOM   4697 C C   . CYS A 1 618  ? 171.381 187.364 151.564 1.00 172.72 ? 636  CYS A C   1 
ATOM   4698 O O   . CYS A 1 618  ? 172.567 187.039 151.495 1.00 162.29 ? 636  CYS A O   1 
ATOM   4699 C CB  . CYS A 1 618  ? 170.864 185.623 149.788 1.00 173.94 ? 636  CYS A CB  1 
ATOM   4700 S SG  . CYS A 1 618  ? 171.543 186.312 148.280 1.00 174.06 ? 636  CYS A SG  1 
ATOM   4701 N N   . GLY A 1 619  ? 170.969 188.385 152.311 1.00 174.66 ? 637  GLY A N   1 
ATOM   4702 C CA  . GLY A 1 619  ? 171.793 188.966 153.353 1.00 165.85 ? 637  GLY A CA  1 
ATOM   4703 C C   . GLY A 1 619  ? 173.058 189.667 152.904 1.00 152.41 ? 637  GLY A C   1 
ATOM   4704 O O   . GLY A 1 619  ? 174.153 189.299 153.339 1.00 150.97 ? 637  GLY A O   1 
ATOM   4705 N N   . LEU A 1 620  ? 172.922 190.667 152.037 1.00 153.13 ? 638  LEU A N   1 
ATOM   4706 C CA  . LEU A 1 620  ? 174.024 191.530 151.631 1.00 145.49 ? 638  LEU A CA  1 
ATOM   4707 C C   . LEU A 1 620  ? 173.729 192.952 152.088 1.00 144.89 ? 638  LEU A C   1 
ATOM   4708 O O   . LEU A 1 620  ? 172.671 193.503 151.767 1.00 153.50 ? 638  LEU A O   1 
ATOM   4709 C CB  . LEU A 1 620  ? 174.217 191.493 150.112 1.00 146.55 ? 638  LEU A CB  1 
ATOM   4710 C CG  . LEU A 1 620  ? 175.625 191.672 149.531 1.00 137.74 ? 638  LEU A CG  1 
ATOM   4711 C CD1 . LEU A 1 620  ? 176.615 190.630 150.046 1.00 133.24 ? 638  LEU A CD1 1 
ATOM   4712 C CD2 . LEU A 1 620  ? 175.573 191.640 148.018 1.00 143.05 ? 638  LEU A CD2 1 
ATOM   4713 N N   . TRP A 1 621  ? 174.664 193.539 152.832 1.00 139.63 ? 639  TRP A N   1 
ATOM   4714 C CA  . TRP A 1 621  ? 174.531 194.884 153.376 1.00 140.14 ? 639  TRP A CA  1 
ATOM   4715 C C   . TRP A 1 621  ? 175.340 195.837 152.507 1.00 139.01 ? 639  TRP A C   1 
ATOM   4716 O O   . TRP A 1 621  ? 176.546 195.637 152.322 1.00 143.68 ? 639  TRP A O   1 
ATOM   4717 C CB  . TRP A 1 621  ? 175.016 194.913 154.823 1.00 141.06 ? 639  TRP A CB  1 
ATOM   4718 C CG  . TRP A 1 621  ? 175.227 196.276 155.385 1.00 148.10 ? 639  TRP A CG  1 
ATOM   4719 C CD1 . TRP A 1 621  ? 174.277 197.227 155.611 1.00 155.90 ? 639  TRP A CD1 1 
ATOM   4720 C CD2 . TRP A 1 621  ? 176.471 196.842 155.806 1.00 147.98 ? 639  TRP A CD2 1 
ATOM   4721 N NE1 . TRP A 1 621  ? 174.853 198.351 156.151 1.00 159.16 ? 639  TRP A NE1 1 
ATOM   4722 C CE2 . TRP A 1 621  ? 176.200 198.139 156.281 1.00 154.23 ? 639  TRP A CE2 1 
ATOM   4723 C CE3 . TRP A 1 621  ? 177.789 196.376 155.833 1.00 144.13 ? 639  TRP A CE3 1 
ATOM   4724 C CZ2 . TRP A 1 621  ? 177.196 198.976 156.773 1.00 155.94 ? 639  TRP A CZ2 1 
ATOM   4725 C CZ3 . TRP A 1 621  ? 178.776 197.208 156.322 1.00 150.74 ? 639  TRP A CZ3 1 
ATOM   4726 C CH2 . TRP A 1 621  ? 178.474 198.494 156.785 1.00 155.23 ? 639  TRP A CH2 1 
ATOM   4727 N N   . VAL A 1 622  ? 174.681 196.874 151.992 1.00 134.89 ? 640  VAL A N   1 
ATOM   4728 C CA  . VAL A 1 622  ? 175.223 197.736 150.947 1.00 137.33 ? 640  VAL A CA  1 
ATOM   4729 C C   . VAL A 1 622  ? 175.256 199.173 151.445 1.00 140.53 ? 640  VAL A C   1 
ATOM   4730 O O   . VAL A 1 622  ? 174.343 199.619 152.147 1.00 143.20 ? 640  VAL A O   1 
ATOM   4731 C CB  . VAL A 1 622  ? 174.402 197.628 149.642 1.00 142.20 ? 640  VAL A CB  1 
ATOM   4732 C CG1 . VAL A 1 622  ? 172.924 197.984 149.869 1.00 150.31 ? 640  VAL A CG1 1 
ATOM   4733 C CG2 . VAL A 1 622  ? 175.001 198.510 148.556 1.00 147.03 ? 640  VAL A CG2 1 
ATOM   4734 N N   . LEU A 1 623  ? 176.319 199.890 151.080 1.00 143.20 ? 641  LEU A N   1 
ATOM   4735 C CA  . LEU A 1 623  ? 176.450 201.321 151.326 1.00 141.27 ? 641  LEU A CA  1 
ATOM   4736 C C   . LEU A 1 623  ? 176.772 201.999 150.006 1.00 150.09 ? 641  LEU A C   1 
ATOM   4737 O O   . LEU A 1 623  ? 177.684 201.569 149.288 1.00 154.19 ? 641  LEU A O   1 
ATOM   4738 C CB  . LEU A 1 623  ? 177.546 201.628 152.348 1.00 139.52 ? 641  LEU A CB  1 
ATOM   4739 C CG  . LEU A 1 623  ? 177.650 200.762 153.602 1.00 144.28 ? 641  LEU A CG  1 
ATOM   4740 C CD1 . LEU A 1 623  ? 178.526 199.538 153.382 1.00 145.88 ? 641  LEU A CD1 1 
ATOM   4741 C CD2 . LEU A 1 623  ? 178.213 201.610 154.720 1.00 154.41 ? 641  LEU A CD2 1 
ATOM   4742 N N   . THR A 1 624  ? 176.028 203.055 149.692 1.00 157.39 ? 642  THR A N   1 
ATOM   4743 C CA  . THR A 1 624  ? 176.251 203.812 148.470 1.00 171.23 ? 642  THR A CA  1 
ATOM   4744 C C   . THR A 1 624  ? 175.556 205.158 148.597 1.00 179.89 ? 642  THR A C   1 
ATOM   4745 O O   . THR A 1 624  ? 174.673 205.345 149.439 1.00 180.28 ? 642  THR A O   1 
ATOM   4746 C CB  . THR A 1 624  ? 175.743 203.058 147.235 1.00 176.00 ? 642  THR A CB  1 
ATOM   4747 O OG1 . THR A 1 624  ? 175.843 203.903 146.082 1.00 186.35 ? 642  THR A OG1 1 
ATOM   4748 C CG2 . THR A 1 624  ? 174.288 202.600 147.410 1.00 174.27 ? 642  THR A CG2 1 
ATOM   4749 N N   . ASP A 1 625  ? 175.968 206.092 147.743 1.00 188.06 ? 643  ASP A N   1 
ATOM   4750 C CA  . ASP A 1 625  ? 175.318 207.389 147.615 1.00 197.88 ? 643  ASP A CA  1 
ATOM   4751 C C   . ASP A 1 625  ? 174.276 207.423 146.503 1.00 205.26 ? 643  ASP A C   1 
ATOM   4752 O O   . ASP A 1 625  ? 173.684 208.481 146.265 1.00 207.94 ? 643  ASP A O   1 
ATOM   4753 C CB  . ASP A 1 625  ? 176.364 208.478 147.361 1.00 198.61 ? 643  ASP A CB  1 
ATOM   4754 C CG  . ASP A 1 625  ? 177.064 208.314 146.027 1.00 203.94 ? 643  ASP A CG  1 
ATOM   4755 O OD1 . ASP A 1 625  ? 177.588 207.212 145.761 1.00 199.11 ? 643  ASP A OD1 1 
ATOM   4756 O OD2 . ASP A 1 625  ? 177.084 209.284 145.241 1.00 208.57 ? 643  ASP A OD2 1 
ATOM   4757 N N   . ALA A 1 626  ? 174.031 206.300 145.824 1.00 205.30 ? 644  ALA A N   1 
ATOM   4758 C CA  . ALA A 1 626  ? 173.161 206.266 144.648 1.00 206.38 ? 644  ALA A CA  1 
ATOM   4759 C C   . ALA A 1 626  ? 171.733 205.880 145.040 1.00 207.03 ? 644  ALA A C   1 
ATOM   4760 O O   . ALA A 1 626  ? 171.158 204.910 144.545 1.00 202.79 ? 644  ALA A O   1 
ATOM   4761 C CB  . ALA A 1 626  ? 173.728 205.304 143.612 1.00 203.26 ? 644  ALA A CB  1 
ATOM   4762 N N   . ASN A 1 627  ? 171.168 206.666 145.963 1.00 209.62 ? 645  ASN A N   1 
ATOM   4763 C CA  . ASN A 1 627  ? 169.777 206.498 146.369 1.00 207.39 ? 645  ASN A CA  1 
ATOM   4764 C C   . ASN A 1 627  ? 169.066 207.827 146.602 1.00 209.37 ? 645  ASN A C   1 
ATOM   4765 O O   . ASN A 1 627  ? 167.973 207.830 147.181 1.00 206.70 ? 645  ASN A O   1 
ATOM   4766 C CB  . ASN A 1 627  ? 169.690 205.644 147.639 1.00 206.86 ? 645  ASN A CB  1 
ATOM   4767 C CG  . ASN A 1 627  ? 170.340 206.313 148.835 1.00 210.60 ? 645  ASN A CG  1 
ATOM   4768 O OD1 . ASN A 1 627  ? 171.549 206.545 148.848 1.00 210.09 ? 645  ASN A OD1 1 
ATOM   4769 N ND2 . ASN A 1 627  ? 169.539 206.627 149.847 1.00 209.58 ? 645  ASN A ND2 1 
ATOM   4770 N N   . LEU A 1 628  ? 169.639 208.950 146.172 1.00 210.65 ? 646  LEU A N   1 
ATOM   4771 C CA  . LEU A 1 628  ? 169.046 210.254 146.438 1.00 209.90 ? 646  LEU A CA  1 
ATOM   4772 C C   . LEU A 1 628  ? 167.913 210.523 145.457 1.00 211.64 ? 646  LEU A C   1 
ATOM   4773 O O   . LEU A 1 628  ? 168.088 210.388 144.241 1.00 211.46 ? 646  LEU A O   1 
ATOM   4774 C CB  . LEU A 1 628  ? 170.098 211.360 146.340 1.00 206.01 ? 646  LEU A CB  1 
ATOM   4775 C CG  . LEU A 1 628  ? 170.648 211.902 147.663 1.00 200.17 ? 646  LEU A CG  1 
ATOM   4776 C CD1 . LEU A 1 628  ? 171.160 210.776 148.553 1.00 200.24 ? 646  LEU A CD1 1 
ATOM   4777 C CD2 . LEU A 1 628  ? 171.744 212.923 147.402 1.00 185.70 ? 646  LEU A CD2 1 
ATOM   4778 N N   . THR A 1 629  ? 166.757 210.911 145.988 1.00 212.56 ? 647  THR A N   1 
ATOM   4779 C CA  . THR A 1 629  ? 165.582 211.222 145.177 1.00 212.69 ? 647  THR A CA  1 
ATOM   4780 C C   . THR A 1 629  ? 165.146 210.014 144.354 1.00 213.07 ? 647  THR A C   1 
ATOM   4781 O O   . THR A 1 629  ? 165.342 208.869 144.763 1.00 211.12 ? 647  THR A O   1 
ATOM   4782 C CB  . THR A 1 629  ? 165.841 212.412 144.225 1.00 210.73 ? 647  THR A CB  1 
ATOM   4783 O OG1 . THR A 1 629  ? 166.708 212.006 143.158 1.00 211.72 ? 647  THR A OG1 1 
ATOM   4784 C CG2 . THR A 1 629  ? 166.474 213.576 144.979 1.00 206.57 ? 647  THR A CG2 1 
ATOM   4785 N N   . HIS A 1 671  ? 164.304 142.994 159.383 1.00 163.47 ? 689  HIS A N   1 
ATOM   4786 C CA  . HIS A 1 671  ? 165.401 143.529 158.587 1.00 162.81 ? 689  HIS A CA  1 
ATOM   4787 C C   . HIS A 1 671  ? 166.545 143.984 159.485 1.00 157.76 ? 689  HIS A C   1 
ATOM   4788 O O   . HIS A 1 671  ? 166.337 144.743 160.432 1.00 156.45 ? 689  HIS A O   1 
ATOM   4789 C CB  . HIS A 1 671  ? 164.920 144.695 157.722 1.00 164.14 ? 689  HIS A CB  1 
ATOM   4790 C CG  . HIS A 1 671  ? 164.217 145.766 158.495 1.00 165.59 ? 689  HIS A CG  1 
ATOM   4791 N ND1 . HIS A 1 671  ? 164.892 146.730 159.212 1.00 160.70 ? 689  HIS A ND1 1 
ATOM   4792 C CD2 . HIS A 1 671  ? 162.899 146.026 158.664 1.00 162.79 ? 689  HIS A CD2 1 
ATOM   4793 C CE1 . HIS A 1 671  ? 164.021 147.537 159.790 1.00 156.46 ? 689  HIS A CE1 1 
ATOM   4794 N NE2 . HIS A 1 671  ? 162.805 147.133 159.473 1.00 155.66 ? 689  HIS A NE2 1 
ATOM   4795 N N   . PHE A 1 672  ? 167.753 143.516 159.178 1.00 156.62 ? 690  PHE A N   1 
ATOM   4796 C CA  . PHE A 1 672  ? 168.942 143.853 159.950 1.00 154.98 ? 690  PHE A CA  1 
ATOM   4797 C C   . PHE A 1 672  ? 170.181 143.723 159.064 1.00 160.79 ? 690  PHE A C   1 
ATOM   4798 O O   . PHE A 1 672  ? 170.513 142.601 158.661 1.00 161.50 ? 690  PHE A O   1 
ATOM   4799 C CB  . PHE A 1 672  ? 169.061 142.940 161.169 1.00 149.53 ? 690  PHE A CB  1 
ATOM   4800 C CG  . PHE A 1 672  ? 168.702 143.610 162.463 1.00 145.68 ? 690  PHE A CG  1 
ATOM   4801 C CD1 . PHE A 1 672  ? 169.634 144.374 163.141 1.00 132.31 ? 690  PHE A CD1 1 
ATOM   4802 C CD2 . PHE A 1 672  ? 167.433 143.483 162.998 1.00 148.71 ? 690  PHE A CD2 1 
ATOM   4803 C CE1 . PHE A 1 672  ? 169.309 144.993 164.330 1.00 117.86 ? 690  PHE A CE1 1 
ATOM   4804 C CE2 . PHE A 1 672  ? 167.103 144.103 164.186 1.00 135.20 ? 690  PHE A CE2 1 
ATOM   4805 C CZ  . PHE A 1 672  ? 168.042 144.858 164.852 1.00 119.23 ? 690  PHE A CZ  1 
ATOM   4806 N N   . PRO A 1 673  ? 170.895 144.801 158.732 1.00 160.63 ? 691  PRO A N   1 
ATOM   4807 C CA  . PRO A 1 673  ? 172.059 144.653 157.856 1.00 154.39 ? 691  PRO A CA  1 
ATOM   4808 C C   . PRO A 1 673  ? 173.256 144.066 158.588 1.00 145.40 ? 691  PRO A C   1 
ATOM   4809 O O   . PRO A 1 673  ? 173.327 144.049 159.818 1.00 139.62 ? 691  PRO A O   1 
ATOM   4810 C CB  . PRO A 1 673  ? 172.346 146.086 157.399 1.00 153.58 ? 691  PRO A CB  1 
ATOM   4811 C CG  . PRO A 1 673  ? 171.878 146.928 158.505 1.00 152.27 ? 691  PRO A CG  1 
ATOM   4812 C CD  . PRO A 1 673  ? 170.727 146.208 159.153 1.00 150.09 ? 691  PRO A CD  1 
ATOM   4813 N N   . GLU A 1 674  ? 174.203 143.574 157.790 1.00 142.32 ? 692  GLU A N   1 
ATOM   4814 C CA  . GLU A 1 674  ? 175.465 143.034 158.275 1.00 137.71 ? 692  GLU A CA  1 
ATOM   4815 C C   . GLU A 1 674  ? 176.601 143.660 157.480 1.00 127.24 ? 692  GLU A C   1 
ATOM   4816 O O   . GLU A 1 674  ? 176.459 143.917 156.281 1.00 129.17 ? 692  GLU A O   1 
ATOM   4817 C CB  . GLU A 1 674  ? 175.506 141.506 158.146 1.00 136.21 ? 692  GLU A CB  1 
ATOM   4818 C CG  . GLU A 1 674  ? 174.962 140.977 156.827 1.00 146.84 ? 692  GLU A CG  1 
ATOM   4819 C CD  . GLU A 1 674  ? 173.497 140.592 156.908 1.00 152.98 ? 692  GLU A CD  1 
ATOM   4820 O OE1 . GLU A 1 674  ? 172.752 141.232 157.679 1.00 150.20 ? 692  GLU A OE1 1 
ATOM   4821 O OE2 . GLU A 1 674  ? 173.089 139.650 156.197 1.00 161.25 ? 692  GLU A OE2 1 
ATOM   4822 N N   . THR A 1 675  ? 177.723 143.899 158.153 1.00 114.95 ? 693  THR A N   1 
ATOM   4823 C CA  . THR A 1 675  ? 178.871 144.578 157.565 1.00 102.92 ? 693  THR A CA  1 
ATOM   4824 C C   . THR A 1 675  ? 179.935 143.558 157.192 1.00 101.92 ? 693  THR A C   1 
ATOM   4825 O O   . THR A 1 675  ? 180.267 142.680 157.996 1.00 108.03 ? 693  THR A O   1 
ATOM   4826 C CB  . THR A 1 675  ? 179.451 145.606 158.537 1.00 107.28 ? 693  THR A CB  1 
ATOM   4827 O OG1 . THR A 1 675  ? 178.386 146.356 159.132 1.00 114.12 ? 693  THR A OG1 1 
ATOM   4828 C CG2 . THR A 1 675  ? 180.394 146.559 157.818 1.00 97.46  ? 693  THR A CG2 1 
ATOM   4829 N N   . TRP A 1 676  ? 180.466 143.680 155.975 1.00 99.67  ? 694  TRP A N   1 
ATOM   4830 C CA  . TRP A 1 676  ? 181.529 142.810 155.486 1.00 97.07  ? 694  TRP A CA  1 
ATOM   4831 C C   . TRP A 1 676  ? 182.897 143.464 155.643 1.00 96.00  ? 694  TRP A C   1 
ATOM   4832 O O   . TRP A 1 676  ? 183.773 142.902 156.307 1.00 100.91 ? 694  TRP A O   1 
ATOM   4833 C CB  . TRP A 1 676  ? 181.269 142.438 154.018 1.00 94.14  ? 694  TRP A CB  1 
ATOM   4834 C CG  . TRP A 1 676  ? 182.310 141.539 153.380 1.00 91.30  ? 694  TRP A CG  1 
ATOM   4835 C CD1 . TRP A 1 676  ? 183.171 140.682 154.009 1.00 93.93  ? 694  TRP A CD1 1 
ATOM   4836 C CD2 . TRP A 1 676  ? 182.585 141.417 151.980 1.00 95.61  ? 694  TRP A CD2 1 
ATOM   4837 N NE1 . TRP A 1 676  ? 183.963 140.044 153.090 1.00 101.04 ? 694  TRP A NE1 1 
ATOM   4838 C CE2 . TRP A 1 676  ? 183.625 140.480 151.837 1.00 98.08  ? 694  TRP A CE2 1 
ATOM   4839 C CE3 . TRP A 1 676  ? 182.055 142.015 150.835 1.00 99.73  ? 694  TRP A CE3 1 
ATOM   4840 C CZ2 . TRP A 1 676  ? 184.137 140.121 150.596 1.00 100.05 ? 694  TRP A CZ2 1 
ATOM   4841 C CZ3 . TRP A 1 676  ? 182.567 141.659 149.605 1.00 97.41  ? 694  TRP A CZ3 1 
ATOM   4842 C CH2 . TRP A 1 676  ? 183.599 140.723 149.494 1.00 99.52  ? 694  TRP A CH2 1 
ATOM   4843 N N   . ILE A 1 677  ? 183.095 144.644 155.052 1.00 94.29  ? 695  ILE A N   1 
ATOM   4844 C CA  . ILE A 1 677  ? 184.404 145.295 155.009 1.00 90.40  ? 695  ILE A CA  1 
ATOM   4845 C C   . ILE A 1 677  ? 184.285 146.657 155.676 1.00 92.22  ? 695  ILE A C   1 
ATOM   4846 O O   . ILE A 1 677  ? 183.376 147.430 155.357 1.00 97.55  ? 695  ILE A O   1 
ATOM   4847 C CB  . ILE A 1 677  ? 184.941 145.437 153.569 1.00 80.49  ? 695  ILE A CB  1 
ATOM   4848 C CG1 . ILE A 1 677  ? 184.805 144.120 152.795 1.00 84.10  ? 695  ILE A CG1 1 
ATOM   4849 C CG2 . ILE A 1 677  ? 186.424 145.847 153.567 1.00 79.09  ? 695  ILE A CG2 1 
ATOM   4850 C CD1 . ILE A 1 677  ? 185.336 144.180 151.379 1.00 88.37  ? 695  ILE A CD1 1 
ATOM   4851 N N   . TRP A 1 678  ? 185.211 146.943 156.586 1.00 85.74  ? 696  TRP A N   1 
ATOM   4852 C CA  . TRP A 1 678  ? 185.377 148.239 157.237 1.00 86.57  ? 696  TRP A CA  1 
ATOM   4853 C C   . TRP A 1 678  ? 186.821 148.702 157.081 1.00 89.81  ? 696  TRP A C   1 
ATOM   4854 O O   . TRP A 1 678  ? 187.509 149.049 158.042 1.00 90.16  ? 696  TRP A O   1 
ATOM   4855 C CB  . TRP A 1 678  ? 184.971 148.169 158.708 1.00 90.61  ? 696  TRP A CB  1 
ATOM   4856 C CG  . TRP A 1 678  ? 184.903 149.509 159.380 1.00 87.65  ? 696  TRP A CG  1 
ATOM   4857 C CD1 . TRP A 1 678  ? 185.739 149.981 160.347 1.00 87.69  ? 696  TRP A CD1 1 
ATOM   4858 C CD2 . TRP A 1 678  ? 183.958 150.551 159.124 1.00 84.27  ? 696  TRP A CD2 1 
ATOM   4859 N NE1 . TRP A 1 678  ? 185.372 151.250 160.712 1.00 88.47  ? 696  TRP A NE1 1 
ATOM   4860 C CE2 . TRP A 1 678  ? 184.280 151.624 159.975 1.00 86.91  ? 696  TRP A CE2 1 
ATOM   4861 C CE3 . TRP A 1 678  ? 182.871 150.682 158.258 1.00 89.89  ? 696  TRP A CE3 1 
ATOM   4862 C CZ2 . TRP A 1 678  ? 183.555 152.808 159.987 1.00 90.08  ? 696  TRP A CZ2 1 
ATOM   4863 C CZ3 . TRP A 1 678  ? 182.151 151.858 158.273 1.00 93.16  ? 696  TRP A CZ3 1 
ATOM   4864 C CH2 . TRP A 1 678  ? 182.496 152.906 159.131 1.00 90.81  ? 696  TRP A CH2 1 
ATOM   4865 N N   . LEU A 1 679  ? 187.311 148.671 155.847 1.00 92.26  ? 697  LEU A N   1 
ATOM   4866 C CA  . LEU A 1 679  ? 188.721 148.934 155.607 1.00 91.18  ? 697  LEU A CA  1 
ATOM   4867 C C   . LEU A 1 679  ? 189.042 150.405 155.832 1.00 97.10  ? 697  LEU A C   1 
ATOM   4868 O O   . LEU A 1 679  ? 188.256 151.289 155.488 1.00 103.17 ? 697  LEU A O   1 
ATOM   4869 C CB  . LEU A 1 679  ? 189.097 148.525 154.184 1.00 89.00  ? 697  LEU A CB  1 
ATOM   4870 C CG  . LEU A 1 679  ? 190.560 148.666 153.760 1.00 97.75  ? 697  LEU A CG  1 
ATOM   4871 C CD1 . LEU A 1 679  ? 191.491 147.894 154.679 1.00 106.33 ? 697  LEU A CD1 1 
ATOM   4872 C CD2 . LEU A 1 679  ? 190.723 148.195 152.328 1.00 104.53 ? 697  LEU A CD2 1 
ATOM   4873 N N   . ASP A 1 680  ? 190.212 150.660 156.412 1.00 97.34  ? 698  ASP A N   1 
ATOM   4874 C CA  . ASP A 1 680  ? 190.705 152.016 156.636 1.00 101.51 ? 698  ASP A CA  1 
ATOM   4875 C C   . ASP A 1 680  ? 192.216 151.976 156.474 1.00 105.14 ? 698  ASP A C   1 
ATOM   4876 O O   . ASP A 1 680  ? 192.912 151.399 157.315 1.00 107.24 ? 698  ASP A O   1 
ATOM   4877 C CB  . ASP A 1 680  ? 190.307 152.527 158.020 1.00 107.48 ? 698  ASP A CB  1 
ATOM   4878 C CG  . ASP A 1 680  ? 190.305 154.036 158.101 1.00 116.25 ? 698  ASP A CG  1 
ATOM   4879 O OD1 . ASP A 1 680  ? 191.247 154.660 157.572 1.00 123.91 ? 698  ASP A OD1 1 
ATOM   4880 O OD2 . ASP A 1 680  ? 189.359 154.598 158.691 1.00 114.83 ? 698  ASP A OD2 1 
ATOM   4881 N N   . THR A 1 681  ? 192.720 152.587 155.401 1.00 106.53 ? 699  THR A N   1 
ATOM   4882 C CA  . THR A 1 681  ? 194.107 152.420 154.976 1.00 109.54 ? 699  THR A CA  1 
ATOM   4883 C C   . THR A 1 681  ? 194.739 153.777 154.720 1.00 112.06 ? 699  THR A C   1 
ATOM   4884 O O   . THR A 1 681  ? 194.167 154.606 154.007 1.00 114.22 ? 699  THR A O   1 
ATOM   4885 C CB  . THR A 1 681  ? 194.186 151.557 153.715 1.00 109.48 ? 699  THR A CB  1 
ATOM   4886 O OG1 . THR A 1 681  ? 193.738 150.230 154.015 1.00 112.94 ? 699  THR A OG1 1 
ATOM   4887 C CG2 . THR A 1 681  ? 195.614 151.503 153.188 1.00 108.66 ? 699  THR A CG2 1 
ATOM   4888 N N   . ASN A 1 682  ? 195.928 153.988 155.279 1.00 112.45 ? 700  ASN A N   1 
ATOM   4889 C CA  . ASN A 1 682  ? 196.724 155.185 155.016 1.00 115.27 ? 700  ASN A CA  1 
ATOM   4890 C C   . ASN A 1 682  ? 197.769 154.824 153.967 1.00 121.00 ? 700  ASN A C   1 
ATOM   4891 O O   . ASN A 1 682  ? 198.849 154.328 154.295 1.00 123.87 ? 700  ASN A O   1 
ATOM   4892 C CB  . ASN A 1 682  ? 197.367 155.696 156.299 1.00 122.97 ? 700  ASN A CB  1 
ATOM   4893 C CG  . ASN A 1 682  ? 197.974 157.075 156.138 1.00 125.16 ? 700  ASN A CG  1 
ATOM   4894 O OD1 . ASN A 1 682  ? 198.045 157.611 155.033 1.00 120.39 ? 700  ASN A OD1 1 
ATOM   4895 N ND2 . ASN A 1 682  ? 198.413 157.660 157.246 1.00 127.47 ? 700  ASN A ND2 1 
ATOM   4896 N N   . MET A 1 683  ? 197.447 155.068 152.700 1.00 122.07 ? 701  MET A N   1 
ATOM   4897 C CA  . MET A 1 683  ? 198.382 154.773 151.625 1.00 124.90 ? 701  MET A CA  1 
ATOM   4898 C C   . MET A 1 683  ? 199.601 155.680 151.723 1.00 135.88 ? 701  MET A C   1 
ATOM   4899 O O   . MET A 1 683  ? 199.486 156.872 152.020 1.00 139.56 ? 701  MET A O   1 
ATOM   4900 C CB  . MET A 1 683  ? 197.709 154.951 150.265 1.00 117.68 ? 701  MET A CB  1 
ATOM   4901 C CG  . MET A 1 683  ? 196.578 153.976 149.990 1.00 110.83 ? 701  MET A CG  1 
ATOM   4902 S SD  . MET A 1 683  ? 195.394 154.629 148.802 1.00 122.40 ? 701  MET A SD  1 
ATOM   4903 C CE  . MET A 1 683  ? 195.376 153.314 147.591 1.00 120.78 ? 701  MET A CE  1 
ATOM   4904 N N   . GLY A 1 684  ? 200.775 155.106 151.467 1.00 137.66 ? 702  GLY A N   1 
ATOM   4905 C CA  . GLY A 1 684  ? 202.023 155.830 151.604 1.00 142.50 ? 702  GLY A CA  1 
ATOM   4906 C C   . GLY A 1 684  ? 202.498 156.476 150.320 1.00 141.85 ? 702  GLY A C   1 
ATOM   4907 O O   . GLY A 1 684  ? 202.818 157.669 150.304 1.00 143.13 ? 702  GLY A O   1 
ATOM   4908 N N   . TYR A 1 685  ? 202.551 155.693 149.239 1.00 138.84 ? 703  TYR A N   1 
ATOM   4909 C CA  . TYR A 1 685  ? 203.068 156.167 147.961 1.00 138.72 ? 703  TYR A CA  1 
ATOM   4910 C C   . TYR A 1 685  ? 202.289 155.665 146.753 1.00 136.37 ? 703  TYR A C   1 
ATOM   4911 O O   . TYR A 1 685  ? 202.703 155.949 145.625 1.00 133.36 ? 703  TYR A O   1 
ATOM   4912 C CB  . TYR A 1 685  ? 204.539 155.754 147.806 1.00 144.93 ? 703  TYR A CB  1 
ATOM   4913 C CG  . TYR A 1 685  ? 204.718 154.307 147.403 1.00 149.64 ? 703  TYR A CG  1 
ATOM   4914 C CD1 . TYR A 1 685  ? 204.470 153.281 148.305 1.00 145.86 ? 703  TYR A CD1 1 
ATOM   4915 C CD2 . TYR A 1 685  ? 205.128 153.967 146.121 1.00 152.72 ? 703  TYR A CD2 1 
ATOM   4916 C CE1 . TYR A 1 685  ? 204.629 151.958 147.942 1.00 151.64 ? 703  TYR A CE1 1 
ATOM   4917 C CE2 . TYR A 1 685  ? 205.289 152.647 145.749 1.00 153.01 ? 703  TYR A CE2 1 
ATOM   4918 C CZ  . TYR A 1 685  ? 205.038 151.647 146.663 1.00 156.50 ? 703  TYR A CZ  1 
ATOM   4919 O OH  . TYR A 1 685  ? 205.197 150.331 146.297 1.00 158.75 ? 703  TYR A OH  1 
ATOM   4920 N N   . ARG A 1 686  ? 201.184 154.948 146.943 1.00 134.54 ? 704  ARG A N   1 
ATOM   4921 C CA  . ARG A 1 686  ? 200.471 154.293 145.855 1.00 132.77 ? 704  ARG A CA  1 
ATOM   4922 C C   . ARG A 1 686  ? 199.226 155.084 145.482 1.00 131.01 ? 704  ARG A C   1 
ATOM   4923 O O   . ARG A 1 686  ? 198.444 155.478 146.351 1.00 134.78 ? 704  ARG A O   1 
ATOM   4924 C CB  . ARG A 1 686  ? 200.070 152.869 146.246 1.00 127.14 ? 704  ARG A CB  1 
ATOM   4925 C CG  . ARG A 1 686  ? 200.972 152.222 147.283 1.00 130.47 ? 704  ARG A CG  1 
ATOM   4926 C CD  . ARG A 1 686  ? 200.733 150.727 147.359 1.00 136.08 ? 704  ARG A CD  1 
ATOM   4927 N NE  . ARG A 1 686  ? 201.521 150.103 148.416 1.00 142.88 ? 704  ARG A NE  1 
ATOM   4928 C CZ  . ARG A 1 686  ? 201.805 148.808 148.496 1.00 147.08 ? 704  ARG A CZ  1 
ATOM   4929 N NH1 . ARG A 1 686  ? 201.369 147.938 147.596 1.00 145.87 ? 704  ARG A NH1 1 
ATOM   4930 N NH2 . ARG A 1 686  ? 202.545 148.370 149.511 1.00 151.07 ? 704  ARG A NH2 1 
ATOM   4931 N N   . ILE A 1 687  ? 199.049 155.313 144.176 1.00 125.19 ? 705  ILE A N   1 
ATOM   4932 C CA  . ILE A 1 687  ? 197.794 155.859 143.667 1.00 120.99 ? 705  ILE A CA  1 
ATOM   4933 C C   . ILE A 1 687  ? 196.716 154.792 143.533 1.00 119.05 ? 705  ILE A C   1 
ATOM   4934 O O   . ILE A 1 687  ? 195.551 155.132 143.287 1.00 123.56 ? 705  ILE A O   1 
ATOM   4935 C CB  . ILE A 1 687  ? 197.995 156.581 142.313 1.00 129.04 ? 705  ILE A CB  1 
ATOM   4936 C CG1 . ILE A 1 687  ? 198.603 155.661 141.240 1.00 130.01 ? 705  ILE A CG1 1 
ATOM   4937 C CG2 . ILE A 1 687  ? 198.874 157.810 142.505 1.00 129.00 ? 705  ILE A CG2 1 
ATOM   4938 C CD1 . ILE A 1 687  ? 198.560 156.251 139.845 1.00 121.18 ? 705  ILE A CD1 1 
ATOM   4939 N N   . TYR A 1 688  ? 197.066 153.514 143.679 1.00 114.70 ? 706  TYR A N   1 
ATOM   4940 C CA  . TYR A 1 688  ? 196.080 152.445 143.690 1.00 116.48 ? 706  TYR A CA  1 
ATOM   4941 C C   . TYR A 1 688  ? 196.613 151.297 144.533 1.00 114.93 ? 706  TYR A C   1 
ATOM   4942 O O   . TYR A 1 688  ? 197.814 151.196 144.795 1.00 114.95 ? 706  TYR A O   1 
ATOM   4943 C CB  . TYR A 1 688  ? 195.735 151.974 142.269 1.00 117.31 ? 706  TYR A CB  1 
ATOM   4944 C CG  . TYR A 1 688  ? 196.484 150.745 141.798 1.00 121.78 ? 706  TYR A CG  1 
ATOM   4945 C CD1 . TYR A 1 688  ? 197.854 150.782 141.557 1.00 126.35 ? 706  TYR A CD1 1 
ATOM   4946 C CD2 . TYR A 1 688  ? 195.816 149.545 141.592 1.00 118.64 ? 706  TYR A CD2 1 
ATOM   4947 C CE1 . TYR A 1 688  ? 198.534 149.659 141.129 1.00 134.30 ? 706  TYR A CE1 1 
ATOM   4948 C CE2 . TYR A 1 688  ? 196.488 148.418 141.163 1.00 133.66 ? 706  TYR A CE2 1 
ATOM   4949 C CZ  . TYR A 1 688  ? 197.846 148.480 140.934 1.00 144.53 ? 706  TYR A CZ  1 
ATOM   4950 O OH  . TYR A 1 688  ? 198.521 147.358 140.506 1.00 153.78 ? 706  TYR A OH  1 
ATOM   4951 N N   . GLN A 1 689  ? 195.697 150.432 144.958 1.00 115.94 ? 707  GLN A N   1 
ATOM   4952 C CA  . GLN A 1 689  ? 196.048 149.291 145.789 1.00 114.68 ? 707  GLN A CA  1 
ATOM   4953 C C   . GLN A 1 689  ? 195.000 148.204 145.619 1.00 114.95 ? 707  GLN A C   1 
ATOM   4954 O O   . GLN A 1 689  ? 193.914 148.435 145.081 1.00 114.95 ? 707  GLN A O   1 
ATOM   4955 C CB  . GLN A 1 689  ? 196.173 149.688 147.263 1.00 116.05 ? 707  GLN A CB  1 
ATOM   4956 C CG  . GLN A 1 689  ? 197.233 148.912 148.025 1.00 123.55 ? 707  GLN A CG  1 
ATOM   4957 C CD  . GLN A 1 689  ? 197.497 149.484 149.401 1.00 138.61 ? 707  GLN A CD  1 
ATOM   4958 O OE1 . GLN A 1 689  ? 196.619 150.094 150.011 1.00 137.38 ? 707  GLN A OE1 1 
ATOM   4959 N NE2 . GLN A 1 689  ? 198.710 149.288 149.900 1.00 148.45 ? 707  GLN A NE2 1 
ATOM   4960 N N   . GLU A 1 690  ? 195.352 147.007 146.085 1.00 111.41 ? 708  GLU A N   1 
ATOM   4961 C CA  . GLU A 1 690  ? 194.506 145.826 146.005 1.00 112.53 ? 708  GLU A CA  1 
ATOM   4962 C C   . GLU A 1 690  ? 194.434 145.174 147.376 1.00 113.21 ? 708  GLU A C   1 
ATOM   4963 O O   . GLU A 1 690  ? 195.424 145.159 148.113 1.00 117.60 ? 708  GLU A O   1 
ATOM   4964 C CB  . GLU A 1 690  ? 195.054 144.828 144.978 1.00 117.59 ? 708  GLU A CB  1 
ATOM   4965 C CG  . GLU A 1 690  ? 194.051 143.790 144.509 1.00 121.34 ? 708  GLU A CG  1 
ATOM   4966 C CD  . GLU A 1 690  ? 194.399 143.210 143.152 1.00 131.11 ? 708  GLU A CD  1 
ATOM   4967 O OE1 . GLU A 1 690  ? 195.587 143.253 142.770 1.00 133.92 ? 708  GLU A OE1 1 
ATOM   4968 O OE2 . GLU A 1 690  ? 193.484 142.708 142.469 1.00 131.37 ? 708  GLU A OE2 1 
ATOM   4969 N N   . PHE A 1 691  ? 193.259 144.644 147.715 1.00 111.87 ? 709  PHE A N   1 
ATOM   4970 C CA  . PHE A 1 691  ? 193.022 144.001 149.003 1.00 109.83 ? 709  PHE A CA  1 
ATOM   4971 C C   . PHE A 1 691  ? 192.273 142.701 148.768 1.00 113.87 ? 709  PHE A C   1 
ATOM   4972 O O   . PHE A 1 691  ? 191.164 142.714 148.228 1.00 120.06 ? 709  PHE A O   1 
ATOM   4973 C CB  . PHE A 1 691  ? 192.222 144.916 149.931 1.00 105.90 ? 709  PHE A CB  1 
ATOM   4974 C CG  . PHE A 1 691  ? 192.980 146.126 150.378 1.00 109.73 ? 709  PHE A CG  1 
ATOM   4975 C CD1 . PHE A 1 691  ? 193.000 147.269 149.600 1.00 110.77 ? 709  PHE A CD1 1 
ATOM   4976 C CD2 . PHE A 1 691  ? 193.679 146.121 151.570 1.00 116.31 ? 709  PHE A CD2 1 
ATOM   4977 C CE1 . PHE A 1 691  ? 193.699 148.385 150.003 1.00 114.58 ? 709  PHE A CE1 1 
ATOM   4978 C CE2 . PHE A 1 691  ? 194.381 147.236 151.978 1.00 122.75 ? 709  PHE A CE2 1 
ATOM   4979 C CZ  . PHE A 1 691  ? 194.391 148.368 151.192 1.00 120.11 ? 709  PHE A CZ  1 
ATOM   4980 N N   . GLU A 1 692  ? 192.873 141.586 149.172 1.00 112.31 ? 710  GLU A N   1 
ATOM   4981 C CA  . GLU A 1 692  ? 192.244 140.278 149.049 1.00 117.21 ? 710  GLU A CA  1 
ATOM   4982 C C   . GLU A 1 692  ? 191.389 140.023 150.283 1.00 109.83 ? 710  GLU A C   1 
ATOM   4983 O O   . GLU A 1 692  ? 191.907 140.002 151.405 1.00 110.08 ? 710  GLU A O   1 
ATOM   4984 C CB  . GLU A 1 692  ? 193.301 139.187 148.889 1.00 130.62 ? 710  GLU A CB  1 
ATOM   4985 C CG  . GLU A 1 692  ? 192.736 137.778 148.827 1.00 137.11 ? 710  GLU A CG  1 
ATOM   4986 C CD  . GLU A 1 692  ? 193.728 136.781 148.264 1.00 160.21 ? 710  GLU A CD  1 
ATOM   4987 O OE1 . GLU A 1 692  ? 194.040 136.867 147.058 1.00 171.70 ? 710  GLU A OE1 1 
ATOM   4988 O OE2 . GLU A 1 692  ? 194.200 135.914 149.029 1.00 165.39 ? 710  GLU A OE2 1 
ATOM   4989 N N   . VAL A 1 693  ? 190.086 139.835 150.075 1.00 107.72 ? 711  VAL A N   1 
ATOM   4990 C CA  . VAL A 1 693  ? 189.132 139.576 151.143 1.00 105.28 ? 711  VAL A CA  1 
ATOM   4991 C C   . VAL A 1 693  ? 188.379 138.293 150.806 1.00 111.06 ? 711  VAL A C   1 
ATOM   4992 O O   . VAL A 1 693  ? 188.527 137.727 149.723 1.00 116.66 ? 711  VAL A O   1 
ATOM   4993 C CB  . VAL A 1 693  ? 188.161 140.755 151.359 1.00 95.25  ? 711  VAL A CB  1 
ATOM   4994 C CG1 . VAL A 1 693  ? 188.913 141.956 151.898 1.00 94.56  ? 711  VAL A CG1 1 
ATOM   4995 C CG2 . VAL A 1 693  ? 187.431 141.126 150.067 1.00 98.40  ? 711  VAL A CG2 1 
ATOM   4996 N N   . THR A 1 694  ? 187.572 137.839 151.760 1.00 111.40 ? 712  THR A N   1 
ATOM   4997 C CA  . THR A 1 694  ? 186.803 136.607 151.645 1.00 113.13 ? 712  THR A CA  1 
ATOM   4998 C C   . THR A 1 694  ? 185.320 136.940 151.633 1.00 116.70 ? 712  THR A C   1 
ATOM   4999 O O   . THR A 1 694  ? 184.852 137.735 152.454 1.00 123.90 ? 712  THR A O   1 
ATOM   5000 C CB  . THR A 1 694  ? 187.118 135.659 152.804 1.00 117.77 ? 712  THR A CB  1 
ATOM   5001 O OG1 . THR A 1 694  ? 188.536 135.594 152.998 1.00 124.35 ? 712  THR A OG1 1 
ATOM   5002 C CG2 . THR A 1 694  ? 186.587 134.261 152.520 1.00 120.30 ? 712  THR A CG2 1 
ATOM   5003 N N   . VAL A 1 695  ? 184.588 136.337 150.707 1.00 112.43 ? 713  VAL A N   1 
ATOM   5004 C CA  . VAL A 1 695  ? 183.134 136.530 150.674 1.00 111.62 ? 713  VAL A CA  1 
ATOM   5005 C C   . VAL A 1 695  ? 182.516 135.782 151.854 1.00 126.63 ? 713  VAL A C   1 
ATOM   5006 O O   . VAL A 1 695  ? 182.817 134.589 152.037 1.00 137.47 ? 713  VAL A O   1 
ATOM   5007 C CB  . VAL A 1 695  ? 182.561 136.031 149.347 1.00 111.20 ? 713  VAL A CB  1 
ATOM   5008 C CG1 . VAL A 1 695  ? 181.038 136.118 149.357 1.00 111.37 ? 713  VAL A CG1 1 
ATOM   5009 C CG2 . VAL A 1 695  ? 183.133 136.834 148.183 1.00 118.89 ? 713  VAL A CG2 1 
ATOM   5010 N N   . PRO A 1 696  ? 181.664 136.396 152.680 1.00 128.55 ? 714  PRO A N   1 
ATOM   5011 C CA  . PRO A 1 696  ? 181.100 135.652 153.811 1.00 139.94 ? 714  PRO A CA  1 
ATOM   5012 C C   . PRO A 1 696  ? 180.109 134.600 153.339 1.00 148.31 ? 714  PRO A C   1 
ATOM   5013 O O   . PRO A 1 696  ? 179.665 134.582 152.190 1.00 149.87 ? 714  PRO A O   1 
ATOM   5014 C CB  . PRO A 1 696  ? 180.407 136.726 154.658 1.00 133.63 ? 714  PRO A CB  1 
ATOM   5015 C CG  . PRO A 1 696  ? 180.827 138.022 154.088 1.00 117.93 ? 714  PRO A CG  1 
ATOM   5016 C CD  . PRO A 1 696  ? 181.118 137.765 152.657 1.00 117.43 ? 714  PRO A CD  1 
ATOM   5017 N N   . ASP A 1 697  ? 179.759 133.707 154.267 1.00 149.86 ? 715  ASP A N   1 
ATOM   5018 C CA  . ASP A 1 697  ? 178.794 132.658 153.965 1.00 152.34 ? 715  ASP A CA  1 
ATOM   5019 C C   . ASP A 1 697  ? 177.411 133.213 153.653 1.00 148.92 ? 715  ASP A C   1 
ATOM   5020 O O   . ASP A 1 697  ? 176.611 132.518 153.018 1.00 148.91 ? 715  ASP A O   1 
ATOM   5021 C CB  . ASP A 1 697  ? 178.702 131.677 155.133 1.00 162.97 ? 715  ASP A CB  1 
ATOM   5022 C CG  . ASP A 1 697  ? 179.795 130.630 155.100 1.00 173.29 ? 715  ASP A CG  1 
ATOM   5023 O OD1 . ASP A 1 697  ? 180.863 130.902 154.511 1.00 165.81 ? 715  ASP A OD1 1 
ATOM   5024 O OD2 . ASP A 1 697  ? 179.588 129.533 155.660 1.00 178.96 ? 715  ASP A OD2 1 
ATOM   5025 N N   . SER A 1 698  ? 177.108 134.434 154.088 1.00 150.79 ? 716  SER A N   1 
ATOM   5026 C CA  . SER A 1 698  ? 175.846 135.065 153.731 1.00 155.81 ? 716  SER A CA  1 
ATOM   5027 C C   . SER A 1 698  ? 175.771 135.249 152.222 1.00 150.35 ? 716  SER A C   1 
ATOM   5028 O O   . SER A 1 698  ? 176.777 135.550 151.572 1.00 145.40 ? 716  SER A O   1 
ATOM   5029 C CB  . SER A 1 698  ? 175.707 136.412 154.438 1.00 153.87 ? 716  SER A CB  1 
ATOM   5030 O OG  . SER A 1 698  ? 174.647 137.169 153.882 1.00 146.82 ? 716  SER A OG  1 
ATOM   5031 N N   . ILE A 1 699  ? 174.575 135.069 151.672 1.00 145.21 ? 717  ILE A N   1 
ATOM   5032 C CA  . ILE A 1 699  ? 174.335 135.070 150.231 1.00 137.68 ? 717  ILE A CA  1 
ATOM   5033 C C   . ILE A 1 699  ? 173.449 136.271 149.930 1.00 133.15 ? 717  ILE A C   1 
ATOM   5034 O O   . ILE A 1 699  ? 172.283 136.315 150.339 1.00 138.92 ? 717  ILE A O   1 
ATOM   5035 C CB  . ILE A 1 699  ? 173.712 133.747 149.751 1.00 137.66 ? 717  ILE A CB  1 
ATOM   5036 C CG1 . ILE A 1 699  ? 173.134 133.890 148.341 1.00 136.12 ? 717  ILE A CG1 1 
ATOM   5037 C CG2 . ILE A 1 699  ? 172.641 133.226 150.729 1.00 141.14 ? 717  ILE A CG2 1 
ATOM   5038 C CD1 . ILE A 1 699  ? 172.975 132.577 147.626 1.00 143.56 ? 717  ILE A CD1 1 
ATOM   5039 N N   . THR A 1 700  ? 173.996 137.250 149.222 1.00 125.03 ? 718  THR A N   1 
ATOM   5040 C CA  . THR A 1 700  ? 173.365 138.565 149.132 1.00 122.25 ? 718  THR A CA  1 
ATOM   5041 C C   . THR A 1 700  ? 174.051 139.357 148.025 1.00 118.37 ? 718  THR A C   1 
ATOM   5042 O O   . THR A 1 700  ? 174.796 138.800 147.212 1.00 125.33 ? 718  THR A O   1 
ATOM   5043 C CB  . THR A 1 700  ? 173.427 139.298 150.473 1.00 126.88 ? 718  THR A CB  1 
ATOM   5044 O OG1 . THR A 1 700  ? 173.048 140.666 150.284 1.00 136.24 ? 718  THR A OG1 1 
ATOM   5045 C CG2 . THR A 1 700  ? 174.831 139.228 151.077 1.00 121.79 ? 718  THR A CG2 1 
ATOM   5046 N N   . SER A 1 701  ? 173.766 140.658 147.977 1.00 111.93 ? 719  SER A N   1 
ATOM   5047 C CA  . SER A 1 701  ? 174.383 141.591 147.036 1.00 111.56 ? 719  SER A CA  1 
ATOM   5048 C C   . SER A 1 701  ? 175.118 142.654 147.843 1.00 108.37 ? 719  SER A C   1 
ATOM   5049 O O   . SER A 1 701  ? 174.532 143.673 148.218 1.00 111.74 ? 719  SER A O   1 
ATOM   5050 C CB  . SER A 1 701  ? 173.336 142.214 146.121 1.00 119.48 ? 719  SER A CB  1 
ATOM   5051 O OG  . SER A 1 701  ? 172.720 141.231 145.309 1.00 132.33 ? 719  SER A OG  1 
ATOM   5052 N N   . TRP A 1 702  ? 176.399 142.420 148.107 1.00 104.53 ? 720  TRP A N   1 
ATOM   5053 C CA  . TRP A 1 702  ? 177.192 143.390 148.845 1.00 102.33 ? 720  TRP A CA  1 
ATOM   5054 C C   . TRP A 1 702  ? 177.371 144.652 148.014 1.00 98.16  ? 720  TRP A C   1 
ATOM   5055 O O   . TRP A 1 702  ? 177.521 144.589 146.791 1.00 101.69 ? 720  TRP A O   1 
ATOM   5056 C CB  . TRP A 1 702  ? 178.552 142.798 149.205 1.00 97.92  ? 720  TRP A CB  1 
ATOM   5057 C CG  . TRP A 1 702  ? 178.445 141.593 150.073 1.00 99.56  ? 720  TRP A CG  1 
ATOM   5058 C CD1 . TRP A 1 702  ? 178.714 140.306 149.723 1.00 106.29 ? 720  TRP A CD1 1 
ATOM   5059 C CD2 . TRP A 1 702  ? 178.023 141.559 151.437 1.00 104.63 ? 720  TRP A CD2 1 
ATOM   5060 N NE1 . TRP A 1 702  ? 178.491 139.470 150.788 1.00 111.29 ? 720  TRP A NE1 1 
ATOM   5061 C CE2 . TRP A 1 702  ? 178.065 140.217 151.854 1.00 111.01 ? 720  TRP A CE2 1 
ATOM   5062 C CE3 . TRP A 1 702  ? 177.616 142.535 152.348 1.00 108.17 ? 720  TRP A CE3 1 
ATOM   5063 C CZ2 . TRP A 1 702  ? 177.715 139.826 153.142 1.00 118.07 ? 720  TRP A CZ2 1 
ATOM   5064 C CZ3 . TRP A 1 702  ? 177.271 142.147 153.626 1.00 118.02 ? 720  TRP A CZ3 1 
ATOM   5065 C CH2 . TRP A 1 702  ? 177.322 140.804 154.011 1.00 123.12 ? 720  TRP A CH2 1 
ATOM   5066 N N   . VAL A 1 703  ? 177.343 145.802 148.683 1.00 94.65  ? 721  VAL A N   1 
ATOM   5067 C CA  . VAL A 1 703  ? 177.538 147.102 148.056 1.00 85.25  ? 721  VAL A CA  1 
ATOM   5068 C C   . VAL A 1 703  ? 178.697 147.775 148.770 1.00 88.35  ? 721  VAL A C   1 
ATOM   5069 O O   . VAL A 1 703  ? 178.700 147.863 150.002 1.00 102.90 ? 721  VAL A O   1 
ATOM   5070 C CB  . VAL A 1 703  ? 176.264 147.966 148.130 1.00 95.47  ? 721  VAL A CB  1 
ATOM   5071 C CG1 . VAL A 1 703  ? 176.576 149.448 147.900 1.00 102.52 ? 721  VAL A CG1 1 
ATOM   5072 C CG2 . VAL A 1 703  ? 175.235 147.467 147.129 1.00 109.09 ? 721  VAL A CG2 1 
ATOM   5073 N N   . ALA A 1 704  ? 179.672 148.243 147.997 1.00 85.03  ? 722  ALA A N   1 
ATOM   5074 C CA  . ALA A 1 704  ? 180.875 148.879 148.512 1.00 82.40  ? 722  ALA A CA  1 
ATOM   5075 C C   . ALA A 1 704  ? 180.902 150.337 148.089 1.00 83.72  ? 722  ALA A C   1 
ATOM   5076 O O   . ALA A 1 704  ? 180.655 150.658 146.918 1.00 98.14  ? 722  ALA A O   1 
ATOM   5077 C CB  . ALA A 1 704  ? 182.132 148.167 148.012 1.00 78.69  ? 722  ALA A CB  1 
ATOM   5078 N N   . THR A 1 705  ? 181.187 151.209 149.053 1.00 76.86  ? 723  THR A N   1 
ATOM   5079 C CA  . THR A 1 705  ? 181.434 152.619 148.810 1.00 79.80  ? 723  THR A CA  1 
ATOM   5080 C C   . THR A 1 705  ? 182.609 153.033 149.681 1.00 82.48  ? 723  THR A C   1 
ATOM   5081 O O   . THR A 1 705  ? 183.110 152.250 150.489 1.00 89.25  ? 723  THR A O   1 
ATOM   5082 C CB  . THR A 1 705  ? 180.195 153.480 149.101 1.00 84.39  ? 723  THR A CB  1 
ATOM   5083 O OG1 . THR A 1 705  ? 180.494 154.855 148.835 1.00 98.66  ? 723  THR A OG1 1 
ATOM   5084 C CG2 . THR A 1 705  ? 179.736 153.339 150.556 1.00 78.35  ? 723  THR A CG2 1 
ATOM   5085 N N   . GLY A 1 706  ? 183.060 154.268 149.514 1.00 82.11  ? 724  GLY A N   1 
ATOM   5086 C CA  . GLY A 1 706  ? 184.206 154.704 150.288 1.00 82.36  ? 724  GLY A CA  1 
ATOM   5087 C C   . GLY A 1 706  ? 184.437 156.189 150.149 1.00 82.13  ? 724  GLY A C   1 
ATOM   5088 O O   . GLY A 1 706  ? 183.643 156.915 149.547 1.00 87.32  ? 724  GLY A O   1 
ATOM   5089 N N   . PHE A 1 707  ? 185.546 156.630 150.733 1.00 79.91  ? 725  PHE A N   1 
ATOM   5090 C CA  . PHE A 1 707  ? 185.933 158.029 150.675 1.00 83.63  ? 725  PHE A CA  1 
ATOM   5091 C C   . PHE A 1 707  ? 187.443 158.143 150.816 1.00 86.47  ? 725  PHE A C   1 
ATOM   5092 O O   . PHE A 1 707  ? 188.109 157.261 151.365 1.00 94.33  ? 725  PHE A O   1 
ATOM   5093 C CB  . PHE A 1 707  ? 185.226 158.854 151.756 1.00 85.09  ? 725  PHE A CB  1 
ATOM   5094 C CG  . PHE A 1 707  ? 185.843 158.732 153.118 1.00 79.26  ? 725  PHE A CG  1 
ATOM   5095 C CD1 . PHE A 1 707  ? 185.677 157.583 153.867 1.00 80.77  ? 725  PHE A CD1 1 
ATOM   5096 C CD2 . PHE A 1 707  ? 186.585 159.769 153.651 1.00 82.44  ? 725  PHE A CD2 1 
ATOM   5097 C CE1 . PHE A 1 707  ? 186.240 157.472 155.120 1.00 81.33  ? 725  PHE A CE1 1 
ATOM   5098 C CE2 . PHE A 1 707  ? 187.151 159.660 154.903 1.00 79.41  ? 725  PHE A CE2 1 
ATOM   5099 C CZ  . PHE A 1 707  ? 186.978 158.511 155.637 1.00 76.99  ? 725  PHE A CZ  1 
ATOM   5100 N N   . VAL A 1 708  ? 187.967 159.257 150.307 1.00 83.82  ? 726  VAL A N   1 
ATOM   5101 C CA  . VAL A 1 708  ? 189.390 159.575 150.304 1.00 84.39  ? 726  VAL A CA  1 
ATOM   5102 C C   . VAL A 1 708  ? 189.550 160.952 150.923 1.00 88.66  ? 726  VAL A C   1 
ATOM   5103 O O   . VAL A 1 708  ? 188.737 161.843 150.664 1.00 95.56  ? 726  VAL A O   1 
ATOM   5104 C CB  . VAL A 1 708  ? 189.969 159.548 148.872 1.00 89.13  ? 726  VAL A CB  1 
ATOM   5105 C CG1 . VAL A 1 708  ? 191.213 160.437 148.724 1.00 93.59  ? 726  VAL A CG1 1 
ATOM   5106 C CG2 . VAL A 1 708  ? 190.315 158.138 148.476 1.00 98.90  ? 726  VAL A CG2 1 
ATOM   5107 N N   . ILE A 1 709  ? 190.591 161.127 151.733 1.00 87.28  ? 727  ILE A N   1 
ATOM   5108 C CA  . ILE A 1 709  ? 190.995 162.438 152.227 1.00 88.75  ? 727  ILE A CA  1 
ATOM   5109 C C   . ILE A 1 709  ? 192.474 162.603 151.916 1.00 98.68  ? 727  ILE A C   1 
ATOM   5110 O O   . ILE A 1 709  ? 193.287 161.730 152.248 1.00 108.86 ? 727  ILE A O   1 
ATOM   5111 C CB  . ILE A 1 709  ? 190.698 162.604 153.727 1.00 79.53  ? 727  ILE A CB  1 
ATOM   5112 C CG1 . ILE A 1 709  ? 189.216 162.953 153.891 1.00 78.37  ? 727  ILE A CG1 1 
ATOM   5113 C CG2 . ILE A 1 709  ? 191.595 163.697 154.365 1.00 89.66  ? 727  ILE A CG2 1 
ATOM   5114 C CD1 . ILE A 1 709  ? 188.700 162.927 155.307 1.00 84.29  ? 727  ILE A CD1 1 
ATOM   5115 N N   . SER A 1 710  ? 192.812 163.712 151.264 1.00 96.29  ? 728  SER A N   1 
ATOM   5116 C CA  . SER A 1 710  ? 194.184 164.086 150.966 1.00 104.73 ? 728  SER A CA  1 
ATOM   5117 C C   . SER A 1 710  ? 194.402 165.538 151.360 1.00 110.45 ? 728  SER A C   1 
ATOM   5118 O O   . SER A 1 710  ? 193.476 166.356 151.314 1.00 112.94 ? 728  SER A O   1 
ATOM   5119 C CB  . SER A 1 710  ? 194.506 163.898 149.484 1.00 114.89 ? 728  SER A CB  1 
ATOM   5120 O OG  . SER A 1 710  ? 195.737 164.514 149.154 1.00 125.27 ? 728  SER A OG  1 
ATOM   5121 N N   . GLU A 1 711  ? 195.645 165.850 151.734 1.00 110.72 ? 729  GLU A N   1 
ATOM   5122 C CA  . GLU A 1 711  ? 195.957 167.171 152.269 1.00 115.30 ? 729  GLU A CA  1 
ATOM   5123 C C   . GLU A 1 711  ? 195.711 168.264 151.238 1.00 123.62 ? 729  GLU A C   1 
ATOM   5124 O O   . GLU A 1 711  ? 195.144 169.313 151.564 1.00 126.23 ? 729  GLU A O   1 
ATOM   5125 C CB  . GLU A 1 711  ? 197.409 167.199 152.751 1.00 117.76 ? 729  GLU A CB  1 
ATOM   5126 C CG  . GLU A 1 711  ? 197.815 168.455 153.527 1.00 129.60 ? 729  GLU A CG  1 
ATOM   5127 C CD  . GLU A 1 711  ? 197.364 168.426 154.973 1.00 141.11 ? 729  GLU A CD  1 
ATOM   5128 O OE1 . GLU A 1 711  ? 196.613 167.504 155.354 1.00 140.51 ? 729  GLU A OE1 1 
ATOM   5129 O OE2 . GLU A 1 711  ? 197.760 169.334 155.733 1.00 152.29 ? 729  GLU A OE2 1 
ATOM   5130 N N   . ASP A 1 712  ? 196.123 168.041 149.991 1.00 127.72 ? 730  ASP A N   1 
ATOM   5131 C CA  . ASP A 1 712  ? 196.019 169.086 148.980 1.00 132.58 ? 730  ASP A CA  1 
ATOM   5132 C C   . ASP A 1 712  ? 194.609 169.161 148.403 1.00 129.66 ? 730  ASP A C   1 
ATOM   5133 O O   . ASP A 1 712  ? 193.949 170.203 148.480 1.00 127.68 ? 730  ASP A O   1 
ATOM   5134 C CB  . ASP A 1 712  ? 197.049 168.846 147.873 1.00 138.78 ? 730  ASP A CB  1 
ATOM   5135 C CG  . ASP A 1 712  ? 197.416 170.118 147.136 1.00 147.84 ? 730  ASP A CG  1 
ATOM   5136 O OD1 . ASP A 1 712  ? 196.589 170.604 146.338 1.00 146.81 ? 730  ASP A OD1 1 
ATOM   5137 O OD2 . ASP A 1 712  ? 198.532 170.632 147.357 1.00 151.69 ? 730  ASP A OD2 1 
ATOM   5138 N N   . LEU A 1 713  ? 194.128 168.060 147.824 1.00 124.80 ? 731  LEU A N   1 
ATOM   5139 C CA  . LEU A 1 713  ? 192.841 168.091 147.139 1.00 122.24 ? 731  LEU A CA  1 
ATOM   5140 C C   . LEU A 1 713  ? 191.688 168.202 148.128 1.00 118.81 ? 731  LEU A C   1 
ATOM   5141 O O   . LEU A 1 713  ? 190.752 168.982 147.916 1.00 118.32 ? 731  LEU A O   1 
ATOM   5142 C CB  . LEU A 1 713  ? 192.684 166.845 146.267 1.00 120.74 ? 731  LEU A CB  1 
ATOM   5143 C CG  . LEU A 1 713  ? 193.835 166.524 145.308 1.00 126.29 ? 731  LEU A CG  1 
ATOM   5144 C CD1 . LEU A 1 713  ? 193.466 165.343 144.426 1.00 130.58 ? 731  LEU A CD1 1 
ATOM   5145 C CD2 . LEU A 1 713  ? 194.216 167.728 144.454 1.00 131.17 ? 731  LEU A CD2 1 
ATOM   5146 N N   . GLY A 1 714  ? 191.737 167.427 149.213 1.00 115.81 ? 732  GLY A N   1 
ATOM   5147 C CA  . GLY A 1 714  ? 190.673 167.402 150.201 1.00 109.59 ? 732  GLY A CA  1 
ATOM   5148 C C   . GLY A 1 714  ? 189.893 166.106 150.179 1.00 105.97 ? 732  GLY A C   1 
ATOM   5149 O O   . GLY A 1 714  ? 190.489 165.028 150.121 1.00 107.92 ? 732  GLY A O   1 
ATOM   5150 N N   . LEU A 1 715  ? 188.566 166.199 150.234 1.00 98.99  ? 733  LEU A N   1 
ATOM   5151 C CA  . LEU A 1 715  ? 187.702 165.030 150.311 1.00 95.98  ? 733  LEU A CA  1 
ATOM   5152 C C   . LEU A 1 715  ? 187.301 164.579 148.914 1.00 101.54 ? 733  LEU A C   1 
ATOM   5153 O O   . LEU A 1 715  ? 187.162 165.395 147.999 1.00 103.77 ? 733  LEU A O   1 
ATOM   5154 C CB  . LEU A 1 715  ? 186.448 165.338 151.134 1.00 91.75  ? 733  LEU A CB  1 
ATOM   5155 C CG  . LEU A 1 715  ? 185.424 164.215 151.362 1.00 89.13  ? 733  LEU A CG  1 
ATOM   5156 C CD1 . LEU A 1 715  ? 185.984 163.155 152.291 1.00 87.74  ? 733  LEU A CD1 1 
ATOM   5157 C CD2 . LEU A 1 715  ? 184.118 164.761 151.904 1.00 97.11  ? 733  LEU A CD2 1 
ATOM   5158 N N   . GLY A 1 716  ? 187.127 163.279 148.763 1.00 103.11 ? 734  GLY A N   1 
ATOM   5159 C CA  . GLY A 1 716  ? 186.567 162.715 147.545 1.00 106.42 ? 734  GLY A CA  1 
ATOM   5160 C C   . GLY A 1 716  ? 185.711 161.514 147.877 1.00 99.13  ? 734  GLY A C   1 
ATOM   5161 O O   . GLY A 1 716  ? 186.006 160.768 148.809 1.00 97.27  ? 734  GLY A O   1 
ATOM   5162 N N   . LEU A 1 717  ? 184.648 161.332 147.098 1.00 95.24  ? 735  LEU A N   1 
ATOM   5163 C CA  . LEU A 1 717  ? 183.653 160.295 147.326 1.00 86.75  ? 735  LEU A CA  1 
ATOM   5164 C C   . LEU A 1 717  ? 183.513 159.425 146.087 1.00 94.89  ? 735  LEU A C   1 
ATOM   5165 O O   . LEU A 1 717  ? 183.810 159.847 144.968 1.00 105.38 ? 735  LEU A O   1 
ATOM   5166 C CB  . LEU A 1 717  ? 182.292 160.905 147.674 1.00 92.10  ? 735  LEU A CB  1 
ATOM   5167 C CG  . LEU A 1 717  ? 181.921 160.939 149.154 1.00 98.35  ? 735  LEU A CG  1 
ATOM   5168 C CD1 . LEU A 1 717  ? 182.827 161.892 149.912 1.00 96.47  ? 735  LEU A CD1 1 
ATOM   5169 C CD2 . LEU A 1 717  ? 180.463 161.332 149.322 1.00 107.11 ? 735  LEU A CD2 1 
ATOM   5170 N N   . THR A 1 718  ? 183.054 158.195 146.300 1.00 93.08  ? 736  THR A N   1 
ATOM   5171 C CA  . THR A 1 718  ? 182.742 157.320 145.181 1.00 99.13  ? 736  THR A CA  1 
ATOM   5172 C C   . THR A 1 718  ? 181.541 157.869 144.427 1.00 107.09 ? 736  THR A C   1 
ATOM   5173 O O   . THR A 1 718  ? 180.526 158.226 145.032 1.00 106.72 ? 736  THR A O   1 
ATOM   5174 C CB  . THR A 1 718  ? 182.454 155.903 145.670 1.00 96.61  ? 736  THR A CB  1 
ATOM   5175 O OG1 . THR A 1 718  ? 181.479 155.946 146.718 1.00 101.44 ? 736  THR A OG1 1 
ATOM   5176 C CG2 . THR A 1 718  ? 183.721 155.248 146.187 1.00 97.02  ? 736  THR A CG2 1 
ATOM   5177 N N   . THR A 1 719  ? 181.661 157.943 143.101 1.00 110.86 ? 737  THR A N   1 
ATOM   5178 C CA  . THR A 1 719  ? 180.576 158.491 142.295 1.00 113.60 ? 737  THR A CA  1 
ATOM   5179 C C   . THR A 1 719  ? 179.340 157.606 142.360 1.00 118.26 ? 737  THR A C   1 
ATOM   5180 O O   . THR A 1 719  ? 178.211 158.110 142.371 1.00 120.64 ? 737  THR A O   1 
ATOM   5181 C CB  . THR A 1 719  ? 181.035 158.663 140.849 1.00 115.10 ? 737  THR A CB  1 
ATOM   5182 O OG1 . THR A 1 719  ? 181.525 157.413 140.349 1.00 118.94 ? 737  THR A OG1 1 
ATOM   5183 C CG2 . THR A 1 719  ? 182.135 159.711 140.759 1.00 109.73 ? 737  THR A CG2 1 
ATOM   5184 N N   . THR A 1 720  ? 179.532 156.290 142.393 1.00 117.85 ? 738  THR A N   1 
ATOM   5185 C CA  . THR A 1 720  ? 178.458 155.315 142.490 1.00 117.50 ? 738  THR A CA  1 
ATOM   5186 C C   . THR A 1 720  ? 178.912 154.175 143.393 1.00 111.98 ? 738  THR A C   1 
ATOM   5187 O O   . THR A 1 720  ? 180.119 153.935 143.514 1.00 110.00 ? 738  THR A O   1 
ATOM   5188 C CB  . THR A 1 720  ? 178.071 154.758 141.109 1.00 117.82 ? 738  THR A CB  1 
ATOM   5189 O OG1 . THR A 1 720  ? 176.938 153.892 141.236 1.00 118.02 ? 738  THR A OG1 1 
ATOM   5190 C CG2 . THR A 1 720  ? 179.227 153.976 140.477 1.00 106.96 ? 738  THR A CG2 1 
ATOM   5191 N N   . PRO A 1 721  ? 177.987 153.458 144.041 1.00 105.34 ? 739  PRO A N   1 
ATOM   5192 C CA  . PRO A 1 721  ? 178.396 152.239 144.746 1.00 96.97  ? 739  PRO A CA  1 
ATOM   5193 C C   . PRO A 1 721  ? 178.723 151.130 143.762 1.00 93.94  ? 739  PRO A C   1 
ATOM   5194 O O   . PRO A 1 721  ? 178.290 151.151 142.607 1.00 101.14 ? 739  PRO A O   1 
ATOM   5195 C CB  . PRO A 1 721  ? 177.176 151.877 145.602 1.00 95.55  ? 739  PRO A CB  1 
ATOM   5196 C CG  . PRO A 1 721  ? 176.235 153.000 145.496 1.00 98.05  ? 739  PRO A CG  1 
ATOM   5197 C CD  . PRO A 1 721  ? 176.558 153.748 144.260 1.00 98.10  ? 739  PRO A CD  1 
ATOM   5198 N N   . VAL A 1 722  ? 179.499 150.153 144.232 1.00 93.65  ? 740  VAL A N   1 
ATOM   5199 C CA  . VAL A 1 722  ? 179.910 149.005 143.426 1.00 90.79  ? 740  VAL A CA  1 
ATOM   5200 C C   . VAL A 1 722  ? 179.300 147.751 144.034 1.00 99.33  ? 740  VAL A C   1 
ATOM   5201 O O   . VAL A 1 722  ? 179.454 147.499 145.234 1.00 105.88 ? 740  VAL A O   1 
ATOM   5202 C CB  . VAL A 1 722  ? 181.441 148.892 143.343 1.00 87.48  ? 740  VAL A CB  1 
ATOM   5203 C CG1 . VAL A 1 722  ? 181.842 148.047 142.148 1.00 95.13  ? 740  VAL A CG1 1 
ATOM   5204 C CG2 . VAL A 1 722  ? 182.066 150.271 143.237 1.00 89.85  ? 740  VAL A CG2 1 
ATOM   5205 N N   . GLU A 1 723  ? 178.625 146.960 143.205 1.00 99.25  ? 741  GLU A N   1 
ATOM   5206 C CA  . GLU A 1 723  ? 177.838 145.819 143.653 1.00 104.87 ? 741  GLU A CA  1 
ATOM   5207 C C   . GLU A 1 723  ? 178.555 144.520 143.317 1.00 98.24  ? 741  GLU A C   1 
ATOM   5208 O O   . GLU A 1 723  ? 179.003 144.330 142.182 1.00 105.53 ? 741  GLU A O   1 
ATOM   5209 C CB  . GLU A 1 723  ? 176.450 145.837 143.008 1.00 114.23 ? 741  GLU A CB  1 
ATOM   5210 C CG  . GLU A 1 723  ? 175.652 144.547 143.186 1.00 120.95 ? 741  GLU A CG  1 
ATOM   5211 C CD  . GLU A 1 723  ? 174.157 144.734 142.981 1.00 134.87 ? 741  GLU A CD  1 
ATOM   5212 O OE1 . GLU A 1 723  ? 173.729 145.841 142.591 1.00 140.20 ? 741  GLU A OE1 1 
ATOM   5213 O OE2 . GLU A 1 723  ? 173.404 143.764 143.207 1.00 143.75 ? 741  GLU A OE2 1 
ATOM   5214 N N   . LEU A 1 724  ? 178.660 143.636 144.308 1.00 96.03  ? 742  LEU A N   1 
ATOM   5215 C CA  . LEU A 1 724  ? 179.160 142.277 144.134 1.00 100.27 ? 742  LEU A CA  1 
ATOM   5216 C C   . LEU A 1 724  ? 178.069 141.324 144.595 1.00 110.24 ? 742  LEU A C   1 
ATOM   5217 O O   . LEU A 1 724  ? 177.704 141.324 145.775 1.00 118.43 ? 742  LEU A O   1 
ATOM   5218 C CB  . LEU A 1 724  ? 180.442 142.052 144.937 1.00 99.94  ? 742  LEU A CB  1 
ATOM   5219 C CG  . LEU A 1 724  ? 180.968 140.614 145.023 1.00 99.11  ? 742  LEU A CG  1 
ATOM   5220 C CD1 . LEU A 1 724  ? 182.473 140.588 144.825 1.00 96.45  ? 742  LEU A CD1 1 
ATOM   5221 C CD2 . LEU A 1 724  ? 180.609 139.952 146.347 1.00 103.68 ? 742  LEU A CD2 1 
ATOM   5222 N N   . GLN A 1 725  ? 177.553 140.514 143.675 1.00 112.81 ? 743  GLN A N   1 
ATOM   5223 C CA  . GLN A 1 725  ? 176.456 139.599 143.983 1.00 115.14 ? 743  GLN A CA  1 
ATOM   5224 C C   . GLN A 1 725  ? 177.047 138.270 144.429 1.00 112.35 ? 743  GLN A C   1 
ATOM   5225 O O   . GLN A 1 725  ? 177.395 137.423 143.603 1.00 119.01 ? 743  GLN A O   1 
ATOM   5226 C CB  . GLN A 1 725  ? 175.538 139.427 142.779 1.00 120.15 ? 743  GLN A CB  1 
ATOM   5227 C CG  . GLN A 1 725  ? 174.396 138.446 143.023 1.00 126.47 ? 743  GLN A CG  1 
ATOM   5228 C CD  . GLN A 1 725  ? 173.269 138.570 142.013 1.00 139.52 ? 743  GLN A CD  1 
ATOM   5229 O OE1 . GLN A 1 725  ? 173.203 139.530 141.246 1.00 141.60 ? 743  GLN A OE1 1 
ATOM   5230 N NE2 . GLN A 1 725  ? 172.371 137.592 142.013 1.00 144.75 ? 743  GLN A NE2 1 
ATOM   5231 N N   . ALA A 1 726  ? 177.160 138.082 145.741 1.00 109.85 ? 744  ALA A N   1 
ATOM   5232 C CA  . ALA A 1 726  ? 177.586 136.805 146.295 1.00 119.18 ? 744  ALA A CA  1 
ATOM   5233 C C   . ALA A 1 726  ? 176.405 135.848 146.219 1.00 130.66 ? 744  ALA A C   1 
ATOM   5234 O O   . ALA A 1 726  ? 175.418 136.014 146.945 1.00 137.24 ? 744  ALA A O   1 
ATOM   5235 C CB  . ALA A 1 726  ? 178.071 136.977 147.730 1.00 128.54 ? 744  ALA A CB  1 
ATOM   5236 N N   . PHE A 1 727  ? 176.508 134.851 145.340 1.00 133.59 ? 745  PHE A N   1 
ATOM   5237 C CA  . PHE A 1 727  ? 175.403 133.958 145.021 1.00 137.48 ? 745  PHE A CA  1 
ATOM   5238 C C   . PHE A 1 727  ? 175.953 132.585 144.663 1.00 140.99 ? 745  PHE A C   1 
ATOM   5239 O O   . PHE A 1 727  ? 177.005 132.480 144.027 1.00 141.56 ? 745  PHE A O   1 
ATOM   5240 C CB  . PHE A 1 727  ? 174.572 134.515 143.855 1.00 136.74 ? 745  PHE A CB  1 
ATOM   5241 C CG  . PHE A 1 727  ? 173.577 133.538 143.289 1.00 144.44 ? 745  PHE A CG  1 
ATOM   5242 C CD1 . PHE A 1 727  ? 172.387 133.281 143.945 1.00 148.58 ? 745  PHE A CD1 1 
ATOM   5243 C CD2 . PHE A 1 727  ? 173.835 132.876 142.101 1.00 148.09 ? 745  PHE A CD2 1 
ATOM   5244 C CE1 . PHE A 1 727  ? 171.473 132.383 143.428 1.00 155.41 ? 745  PHE A CE1 1 
ATOM   5245 C CE2 . PHE A 1 727  ? 172.925 131.977 141.580 1.00 151.77 ? 745  PHE A CE2 1 
ATOM   5246 C CZ  . PHE A 1 727  ? 171.743 131.731 142.245 1.00 155.86 ? 745  PHE A CZ  1 
ATOM   5247 N N   . GLN A 1 728  ? 175.241 131.543 145.083 1.00 143.46 ? 746  GLN A N   1 
ATOM   5248 C CA  . GLN A 1 728  ? 175.469 130.177 144.641 1.00 150.08 ? 746  GLN A CA  1 
ATOM   5249 C C   . GLN A 1 728  ? 174.128 129.542 144.298 1.00 157.20 ? 746  GLN A C   1 
ATOM   5250 O O   . GLN A 1 728  ? 173.096 129.958 144.833 1.00 157.56 ? 746  GLN A O   1 
ATOM   5251 C CB  . GLN A 1 728  ? 176.190 129.351 145.717 1.00 149.69 ? 746  GLN A CB  1 
ATOM   5252 C CG  . GLN A 1 728  ? 175.527 129.350 147.086 1.00 156.71 ? 746  GLN A CG  1 
ATOM   5253 C CD  . GLN A 1 728  ? 176.194 128.386 148.048 1.00 164.32 ? 746  GLN A CD  1 
ATOM   5254 O OE1 . GLN A 1 728  ? 177.058 127.601 147.660 1.00 165.28 ? 746  GLN A OE1 1 
ATOM   5255 N NE2 . GLN A 1 728  ? 175.797 128.444 149.313 1.00 168.13 ? 746  GLN A NE2 1 
ATOM   5256 N N   . PRO A 1 729  ? 174.102 128.539 143.418 1.00 163.47 ? 747  PRO A N   1 
ATOM   5257 C CA  . PRO A 1 729  ? 172.821 128.048 142.896 1.00 170.36 ? 747  PRO A CA  1 
ATOM   5258 C C   . PRO A 1 729  ? 172.097 127.052 143.790 1.00 171.18 ? 747  PRO A C   1 
ATOM   5259 O O   . PRO A 1 729  ? 171.072 126.510 143.368 1.00 176.58 ? 747  PRO A O   1 
ATOM   5260 C CB  . PRO A 1 729  ? 173.241 127.385 141.577 1.00 169.66 ? 747  PRO A CB  1 
ATOM   5261 C CG  . PRO A 1 729  ? 174.574 126.834 141.872 1.00 164.15 ? 747  PRO A CG  1 
ATOM   5262 C CD  . PRO A 1 729  ? 175.235 127.808 142.815 1.00 161.35 ? 747  PRO A CD  1 
ATOM   5263 N N   . PHE A 1 730  ? 172.585 126.790 145.000 1.00 160.11 ? 748  PHE A N   1 
ATOM   5264 C CA  . PHE A 1 730  ? 171.939 125.839 145.903 1.00 161.74 ? 748  PHE A CA  1 
ATOM   5265 C C   . PHE A 1 730  ? 172.419 126.151 147.311 1.00 158.27 ? 748  PHE A C   1 
ATOM   5266 O O   . PHE A 1 730  ? 173.625 126.102 147.568 1.00 156.39 ? 748  PHE A O   1 
ATOM   5267 C CB  . PHE A 1 730  ? 172.271 124.403 145.515 1.00 166.61 ? 748  PHE A CB  1 
ATOM   5268 C CG  . PHE A 1 730  ? 171.798 123.384 146.509 1.00 172.37 ? 748  PHE A CG  1 
ATOM   5269 C CD1 . PHE A 1 730  ? 170.448 123.119 146.662 1.00 176.05 ? 748  PHE A CD1 1 
ATOM   5270 C CD2 . PHE A 1 730  ? 172.705 122.693 147.293 1.00 174.45 ? 748  PHE A CD2 1 
ATOM   5271 C CE1 . PHE A 1 730  ? 170.013 122.181 147.576 1.00 180.60 ? 748  PHE A CE1 1 
ATOM   5272 C CE2 . PHE A 1 730  ? 172.275 121.754 148.208 1.00 177.48 ? 748  PHE A CE2 1 
ATOM   5273 C CZ  . PHE A 1 730  ? 170.928 121.498 148.351 1.00 182.31 ? 748  PHE A CZ  1 
ATOM   5274 N N   . PHE A 1 731  ? 171.496 126.471 148.217 1.00 159.14 ? 749  PHE A N   1 
ATOM   5275 C CA  . PHE A 1 731  ? 171.905 126.934 149.537 1.00 156.35 ? 749  PHE A CA  1 
ATOM   5276 C C   . PHE A 1 731  ? 170.774 126.763 150.545 1.00 158.87 ? 749  PHE A C   1 
ATOM   5277 O O   . PHE A 1 731  ? 169.670 126.315 150.218 1.00 165.45 ? 749  PHE A O   1 
ATOM   5278 C CB  . PHE A 1 731  ? 172.378 128.390 149.471 1.00 151.58 ? 749  PHE A CB  1 
ATOM   5279 C CG  . PHE A 1 731  ? 171.299 129.367 149.108 1.00 148.47 ? 749  PHE A CG  1 
ATOM   5280 C CD1 . PHE A 1 731  ? 170.957 129.580 147.784 1.00 155.21 ? 749  PHE A CD1 1 
ATOM   5281 C CD2 . PHE A 1 731  ? 170.636 130.082 150.088 1.00 147.79 ? 749  PHE A CD2 1 
ATOM   5282 C CE1 . PHE A 1 731  ? 169.972 130.485 147.446 1.00 157.46 ? 749  PHE A CE1 1 
ATOM   5283 C CE2 . PHE A 1 731  ? 169.649 130.987 149.756 1.00 152.83 ? 749  PHE A CE2 1 
ATOM   5284 C CZ  . PHE A 1 731  ? 169.318 131.190 148.433 1.00 155.36 ? 749  PHE A CZ  1 
ATOM   5285 N N   . ILE A 1 732  ? 171.080 127.137 151.788 1.00 154.46 ? 750  ILE A N   1 
ATOM   5286 C CA  . ILE A 1 732  ? 170.221 126.955 152.951 1.00 150.18 ? 750  ILE A CA  1 
ATOM   5287 C C   . ILE A 1 732  ? 169.984 128.330 153.558 1.00 147.90 ? 750  ILE A C   1 
ATOM   5288 O O   . ILE A 1 732  ? 170.888 129.173 153.566 1.00 147.11 ? 750  ILE A O   1 
ATOM   5289 C CB  . ILE A 1 732  ? 170.856 126.000 153.995 1.00 151.32 ? 750  ILE A CB  1 
ATOM   5290 C CG1 . ILE A 1 732  ? 171.411 124.719 153.343 1.00 164.97 ? 750  ILE A CG1 1 
ATOM   5291 C CG2 . ILE A 1 732  ? 169.856 125.618 155.099 1.00 153.37 ? 750  ILE A CG2 1 
ATOM   5292 C CD1 . ILE A 1 732  ? 172.197 123.837 154.295 1.00 171.45 ? 750  ILE A CD1 1 
ATOM   5293 N N   . PHE A 1 733  ? 168.768 128.559 154.056 1.00 151.61 ? 751  PHE A N   1 
ATOM   5294 C CA  . PHE A 1 733  ? 168.419 129.791 154.748 1.00 152.41 ? 751  PHE A CA  1 
ATOM   5295 C C   . PHE A 1 733  ? 167.662 129.462 156.025 1.00 153.61 ? 751  PHE A C   1 
ATOM   5296 O O   . PHE A 1 733  ? 166.829 128.550 156.047 1.00 156.59 ? 751  PHE A O   1 
ATOM   5297 C CB  . PHE A 1 733  ? 167.569 130.704 153.860 1.00 153.92 ? 751  PHE A CB  1 
ATOM   5298 C CG  . PHE A 1 733  ? 167.150 131.978 154.531 1.00 153.86 ? 751  PHE A CG  1 
ATOM   5299 C CD1 . PHE A 1 733  ? 168.091 132.920 154.908 1.00 153.13 ? 751  PHE A CD1 1 
ATOM   5300 C CD2 . PHE A 1 733  ? 165.815 132.230 154.791 1.00 158.99 ? 751  PHE A CD2 1 
ATOM   5301 C CE1 . PHE A 1 733  ? 167.707 134.092 155.527 1.00 155.32 ? 751  PHE A CE1 1 
ATOM   5302 C CE2 . PHE A 1 733  ? 165.425 133.400 155.410 1.00 161.33 ? 751  PHE A CE2 1 
ATOM   5303 C CZ  . PHE A 1 733  ? 166.373 134.332 155.779 1.00 160.02 ? 751  PHE A CZ  1 
ATOM   5304 N N   . LEU A 1 734  ? 167.969 130.205 157.087 1.00 150.40 ? 752  LEU A N   1 
ATOM   5305 C CA  . LEU A 1 734  ? 167.296 130.085 158.374 1.00 152.27 ? 752  LEU A CA  1 
ATOM   5306 C C   . LEU A 1 734  ? 166.788 131.454 158.799 1.00 157.49 ? 752  LEU A C   1 
ATOM   5307 O O   . LEU A 1 734  ? 167.576 132.397 158.933 1.00 157.66 ? 752  LEU A O   1 
ATOM   5308 C CB  . LEU A 1 734  ? 168.236 129.524 159.442 1.00 147.12 ? 752  LEU A CB  1 
ATOM   5309 C CG  . LEU A 1 734  ? 169.068 128.302 159.054 1.00 144.08 ? 752  LEU A CG  1 
ATOM   5310 C CD1 . LEU A 1 734  ? 170.499 128.708 158.750 1.00 149.49 ? 752  LEU A CD1 1 
ATOM   5311 C CD2 . LEU A 1 734  ? 169.031 127.264 160.161 1.00 143.55 ? 752  LEU A CD2 1 
ATOM   5312 N N   . ASN A 1 735  ? 165.480 131.556 159.013 1.00 159.01 ? 753  ASN A N   1 
ATOM   5313 C CA  . ASN A 1 735  ? 164.861 132.771 159.550 1.00 160.13 ? 753  ASN A CA  1 
ATOM   5314 C C   . ASN A 1 735  ? 164.721 132.651 161.066 1.00 158.87 ? 753  ASN A C   1 
ATOM   5315 O O   . ASN A 1 735  ? 163.635 132.739 161.637 1.00 166.69 ? 753  ASN A O   1 
ATOM   5316 C CB  . ASN A 1 735  ? 163.508 133.027 158.887 1.00 168.61 ? 753  ASN A CB  1 
ATOM   5317 C CG  . ASN A 1 735  ? 162.561 131.847 159.005 1.00 179.50 ? 753  ASN A CG  1 
ATOM   5318 O OD1 . ASN A 1 735  ? 162.995 130.713 159.202 1.00 175.65 ? 753  ASN A OD1 1 
ATOM   5319 N ND2 . ASN A 1 735  ? 161.264 132.109 158.893 1.00 189.19 ? 753  ASN A ND2 1 
ATOM   5320 N N   . LEU A 1 736  ? 165.857 132.439 161.716 1.00 151.15 ? 754  LEU A N   1 
ATOM   5321 C CA  . LEU A 1 736  ? 165.844 132.134 163.137 1.00 145.18 ? 754  LEU A CA  1 
ATOM   5322 C C   . LEU A 1 736  ? 165.461 133.377 163.942 1.00 147.45 ? 754  LEU A C   1 
ATOM   5323 O O   . LEU A 1 736  ? 165.739 134.500 163.511 1.00 151.23 ? 754  LEU A O   1 
ATOM   5324 C CB  . LEU A 1 736  ? 167.214 131.632 163.582 1.00 141.61 ? 754  LEU A CB  1 
ATOM   5325 C CG  . LEU A 1 736  ? 167.493 130.141 163.369 1.00 150.70 ? 754  LEU A CG  1 
ATOM   5326 C CD1 . LEU A 1 736  ? 168.975 129.844 163.545 1.00 155.58 ? 754  LEU A CD1 1 
ATOM   5327 C CD2 . LEU A 1 736  ? 166.658 129.268 164.297 1.00 157.78 ? 754  LEU A CD2 1 
ATOM   5328 N N   . PRO A 1 737  ? 164.830 133.220 165.108 1.00 142.83 ? 755  PRO A N   1 
ATOM   5329 C CA  . PRO A 1 737  ? 164.516 134.393 165.931 1.00 138.30 ? 755  PRO A CA  1 
ATOM   5330 C C   . PRO A 1 737  ? 165.738 134.865 166.703 1.00 135.70 ? 755  PRO A C   1 
ATOM   5331 O O   . PRO A 1 737  ? 166.738 134.160 166.841 1.00 144.65 ? 755  PRO A O   1 
ATOM   5332 C CB  . PRO A 1 737  ? 163.422 133.885 166.869 1.00 137.87 ? 755  PRO A CB  1 
ATOM   5333 C CG  . PRO A 1 737  ? 163.739 132.454 167.043 1.00 135.91 ? 755  PRO A CG  1 
ATOM   5334 C CD  . PRO A 1 737  ? 164.340 131.981 165.745 1.00 139.84 ? 755  PRO A CD  1 
ATOM   5335 N N   . TYR A 1 738  ? 165.644 136.094 167.213 1.00 129.01 ? 756  TYR A N   1 
ATOM   5336 C CA  . TYR A 1 738  ? 166.747 136.649 167.991 1.00 133.48 ? 756  TYR A CA  1 
ATOM   5337 C C   . TYR A 1 738  ? 166.958 135.871 169.282 1.00 139.28 ? 756  TYR A C   1 
ATOM   5338 O O   . TYR A 1 738  ? 168.097 135.571 169.656 1.00 146.50 ? 756  TYR A O   1 
ATOM   5339 C CB  . TYR A 1 738  ? 166.493 138.120 168.307 1.00 136.38 ? 756  TYR A CB  1 
ATOM   5340 C CG  . TYR A 1 738  ? 167.532 138.702 169.236 1.00 138.82 ? 756  TYR A CG  1 
ATOM   5341 C CD1 . TYR A 1 738  ? 168.849 138.848 168.828 1.00 140.06 ? 756  TYR A CD1 1 
ATOM   5342 C CD2 . TYR A 1 738  ? 167.201 139.085 170.527 1.00 136.82 ? 756  TYR A CD2 1 
ATOM   5343 C CE1 . TYR A 1 738  ? 169.805 139.370 169.673 1.00 134.78 ? 756  TYR A CE1 1 
ATOM   5344 C CE2 . TYR A 1 738  ? 168.151 139.608 171.381 1.00 136.58 ? 756  TYR A CE2 1 
ATOM   5345 C CZ  . TYR A 1 738  ? 169.451 139.747 170.948 1.00 138.04 ? 756  TYR A CZ  1 
ATOM   5346 O OH  . TYR A 1 738  ? 170.403 140.265 171.792 1.00 137.30 ? 756  TYR A OH  1 
ATOM   5347 N N   . SER A 1 739  ? 165.873 135.545 169.980 1.00 136.95 ? 757  SER A N   1 
ATOM   5348 C CA  . SER A 1 739  ? 165.967 134.895 171.278 1.00 138.37 ? 757  SER A CA  1 
ATOM   5349 C C   . SER A 1 739  ? 164.752 134.012 171.500 1.00 141.60 ? 757  SER A C   1 
ATOM   5350 O O   . SER A 1 739  ? 163.658 134.310 171.014 1.00 145.87 ? 757  SER A O   1 
ATOM   5351 C CB  . SER A 1 739  ? 166.071 135.923 172.409 1.00 139.53 ? 757  SER A CB  1 
ATOM   5352 O OG  . SER A 1 739  ? 164.783 136.319 172.847 1.00 152.10 ? 757  SER A OG  1 
ATOM   5353 N N   . VAL A 1 740  ? 164.964 132.924 172.236 1.00 141.34 ? 758  VAL A N   1 
ATOM   5354 C CA  . VAL A 1 740  ? 163.905 132.028 172.673 1.00 143.08 ? 758  VAL A CA  1 
ATOM   5355 C C   . VAL A 1 740  ? 164.096 131.775 174.161 1.00 147.92 ? 758  VAL A C   1 
ATOM   5356 O O   . VAL A 1 740  ? 165.149 132.066 174.735 1.00 150.78 ? 758  VAL A O   1 
ATOM   5357 C CB  . VAL A 1 740  ? 163.888 130.701 171.882 1.00 138.21 ? 758  VAL A CB  1 
ATOM   5358 C CG1 . VAL A 1 740  ? 163.642 130.971 170.407 1.00 138.87 ? 758  VAL A CG1 1 
ATOM   5359 C CG2 . VAL A 1 740  ? 165.187 129.920 172.075 1.00 139.80 ? 758  VAL A CG2 1 
ATOM   5360 N N   . ILE A 1 741  ? 163.059 131.218 174.783 1.00 147.24 ? 759  ILE A N   1 
ATOM   5361 C CA  . ILE A 1 741  ? 163.047 130.948 176.220 1.00 149.23 ? 759  ILE A CA  1 
ATOM   5362 C C   . ILE A 1 741  ? 163.275 129.460 176.438 1.00 151.21 ? 759  ILE A C   1 
ATOM   5363 O O   . ILE A 1 741  ? 162.661 128.617 175.772 1.00 154.31 ? 759  ILE A O   1 
ATOM   5364 C CB  . ILE A 1 741  ? 161.739 131.419 176.893 1.00 153.32 ? 759  ILE A CB  1 
ATOM   5365 C CG1 . ILE A 1 741  ? 160.494 130.988 176.112 1.00 156.22 ? 759  ILE A CG1 1 
ATOM   5366 C CG2 . ILE A 1 741  ? 161.746 132.930 177.046 1.00 155.64 ? 759  ILE A CG2 1 
ATOM   5367 C CD1 . ILE A 1 741  ? 159.265 130.813 176.976 1.00 159.12 ? 759  ILE A CD1 1 
ATOM   5368 N N   . ARG A 1 742  ? 164.176 129.141 177.363 1.00 154.77 ? 760  ARG A N   1 
ATOM   5369 C CA  . ARG A 1 742  ? 164.535 127.755 177.630 1.00 161.32 ? 760  ARG A CA  1 
ATOM   5370 C C   . ARG A 1 742  ? 163.329 126.978 178.141 1.00 168.02 ? 760  ARG A C   1 
ATOM   5371 O O   . ARG A 1 742  ? 162.487 127.510 178.868 1.00 170.59 ? 760  ARG A O   1 
ATOM   5372 C CB  . ARG A 1 742  ? 165.670 127.699 178.653 1.00 159.16 ? 760  ARG A CB  1 
ATOM   5373 C CG  . ARG A 1 742  ? 166.302 126.320 178.835 1.00 159.27 ? 760  ARG A CG  1 
ATOM   5374 C CD  . ARG A 1 742  ? 167.333 126.312 179.958 1.00 160.24 ? 760  ARG A CD  1 
ATOM   5375 N NE  . ARG A 1 742  ? 166.747 126.647 181.252 1.00 162.75 ? 760  ARG A NE  1 
ATOM   5376 C CZ  . ARG A 1 742  ? 167.407 126.679 182.404 1.00 166.95 ? 760  ARG A CZ  1 
ATOM   5377 N NH1 . ARG A 1 742  ? 168.700 126.397 182.477 1.00 166.46 ? 760  ARG A NH1 1 
ATOM   5378 N NH2 . ARG A 1 742  ? 166.753 127.004 183.515 1.00 166.26 ? 760  ARG A NH2 1 
ATOM   5379 N N   . GLY A 1 743  ? 163.251 125.708 177.751 1.00 169.20 ? 761  GLY A N   1 
ATOM   5380 C CA  . GLY A 1 743  ? 162.142 124.857 178.120 1.00 169.99 ? 761  GLY A CA  1 
ATOM   5381 C C   . GLY A 1 743  ? 160.907 124.997 177.257 1.00 169.19 ? 761  GLY A C   1 
ATOM   5382 O O   . GLY A 1 743  ? 159.922 124.288 177.501 1.00 168.61 ? 761  GLY A O   1 
ATOM   5383 N N   . GLU A 1 744  ? 160.927 125.879 176.259 1.00 169.34 ? 762  GLU A N   1 
ATOM   5384 C CA  . GLU A 1 744  ? 159.800 126.111 175.366 1.00 174.95 ? 762  GLU A CA  1 
ATOM   5385 C C   . GLU A 1 744  ? 160.092 125.474 174.016 1.00 179.59 ? 762  GLU A C   1 
ATOM   5386 O O   . GLU A 1 744  ? 161.194 125.625 173.479 1.00 177.82 ? 762  GLU A O   1 
ATOM   5387 C CB  . GLU A 1 744  ? 159.541 127.607 175.195 1.00 176.94 ? 762  GLU A CB  1 
ATOM   5388 C CG  . GLU A 1 744  ? 158.370 127.938 174.273 1.00 186.67 ? 762  GLU A CG  1 
ATOM   5389 C CD  . GLU A 1 744  ? 158.794 128.297 172.856 1.00 189.39 ? 762  GLU A CD  1 
ATOM   5390 O OE1 . GLU A 1 744  ? 159.779 129.046 172.683 1.00 185.65 ? 762  GLU A OE1 1 
ATOM   5391 O OE2 . GLU A 1 744  ? 158.131 127.829 171.907 1.00 191.19 ? 762  GLU A OE2 1 
ATOM   5392 N N   . GLU A 1 745  ? 159.104 124.770 173.472 1.00 182.99 ? 763  GLU A N   1 
ATOM   5393 C CA  . GLU A 1 745  ? 159.245 124.081 172.192 1.00 182.71 ? 763  GLU A CA  1 
ATOM   5394 C C   . GLU A 1 745  ? 158.896 125.061 171.080 1.00 179.14 ? 763  GLU A C   1 
ATOM   5395 O O   . GLU A 1 745  ? 157.720 125.312 170.808 1.00 180.41 ? 763  GLU A O   1 
ATOM   5396 C CB  . GLU A 1 745  ? 158.348 122.849 172.137 1.00 190.88 ? 763  GLU A CB  1 
ATOM   5397 C CG  . GLU A 1 745  ? 158.532 121.845 173.286 1.00 194.27 ? 763  GLU A CG  1 
ATOM   5398 C CD  . GLU A 1 745  ? 157.333 120.933 173.483 1.00 203.14 ? 763  GLU A CD  1 
ATOM   5399 O OE1 . GLU A 1 745  ? 156.408 120.954 172.643 1.00 207.34 ? 763  GLU A OE1 1 
ATOM   5400 O OE2 . GLU A 1 745  ? 157.316 120.189 174.486 1.00 202.90 ? 763  GLU A OE2 1 
ATOM   5401 N N   . PHE A 1 746  ? 159.919 125.614 170.430 1.00 176.10 ? 764  PHE A N   1 
ATOM   5402 C CA  . PHE A 1 746  ? 159.746 126.607 169.381 1.00 173.47 ? 764  PHE A CA  1 
ATOM   5403 C C   . PHE A 1 746  ? 159.974 125.972 168.016 1.00 171.59 ? 764  PHE A C   1 
ATOM   5404 O O   . PHE A 1 746  ? 160.585 124.907 167.887 1.00 172.27 ? 764  PHE A O   1 
ATOM   5405 C CB  . PHE A 1 746  ? 160.696 127.794 169.589 1.00 167.26 ? 764  PHE A CB  1 
ATOM   5406 C CG  . PHE A 1 746  ? 161.960 127.719 168.782 1.00 164.11 ? 764  PHE A CG  1 
ATOM   5407 C CD1 . PHE A 1 746  ? 162.991 126.877 169.156 1.00 166.63 ? 764  PHE A CD1 1 
ATOM   5408 C CD2 . PHE A 1 746  ? 162.122 128.510 167.657 1.00 158.15 ? 764  PHE A CD2 1 
ATOM   5409 C CE1 . PHE A 1 746  ? 164.156 126.817 168.416 1.00 165.73 ? 764  PHE A CE1 1 
ATOM   5410 C CE2 . PHE A 1 746  ? 163.282 128.452 166.914 1.00 158.55 ? 764  PHE A CE2 1 
ATOM   5411 C CZ  . PHE A 1 746  ? 164.300 127.605 167.294 1.00 163.19 ? 764  PHE A CZ  1 
ATOM   5412 N N   . ALA A 1 747  ? 159.470 126.647 166.988 1.00 169.64 ? 765  ALA A N   1 
ATOM   5413 C CA  . ALA A 1 747  ? 159.495 126.142 165.623 1.00 168.25 ? 765  ALA A CA  1 
ATOM   5414 C C   . ALA A 1 747  ? 160.716 126.681 164.892 1.00 167.05 ? 765  ALA A C   1 
ATOM   5415 O O   . ALA A 1 747  ? 160.961 127.892 164.894 1.00 165.71 ? 765  ALA A O   1 
ATOM   5416 C CB  . ALA A 1 747  ? 158.220 126.538 164.879 1.00 168.27 ? 765  ALA A CB  1 
ATOM   5417 N N   . LEU A 1 748  ? 161.473 125.780 164.271 1.00 166.53 ? 766  LEU A N   1 
ATOM   5418 C CA  . LEU A 1 748  ? 162.621 126.118 163.442 1.00 165.57 ? 766  LEU A CA  1 
ATOM   5419 C C   . LEU A 1 748  ? 162.263 125.837 161.991 1.00 168.38 ? 766  LEU A C   1 
ATOM   5420 O O   . LEU A 1 748  ? 161.898 124.708 161.650 1.00 170.94 ? 766  LEU A O   1 
ATOM   5421 C CB  . LEU A 1 748  ? 163.850 125.311 163.875 1.00 163.49 ? 766  LEU A CB  1 
ATOM   5422 C CG  . LEU A 1 748  ? 164.987 125.027 162.888 1.00 167.85 ? 766  LEU A CG  1 
ATOM   5423 C CD1 . LEU A 1 748  ? 165.634 126.311 162.416 1.00 170.45 ? 766  LEU A CD1 1 
ATOM   5424 C CD2 . LEU A 1 748  ? 166.017 124.140 163.558 1.00 172.59 ? 766  LEU A CD2 1 
ATOM   5425 N N   . GLU A 1 749  ? 162.373 126.860 161.146 1.00 170.79 ? 767  GLU A N   1 
ATOM   5426 C CA  . GLU A 1 749  ? 162.052 126.765 159.728 1.00 176.16 ? 767  GLU A CA  1 
ATOM   5427 C C   . GLU A 1 749  ? 163.339 126.866 158.924 1.00 173.69 ? 767  GLU A C   1 
ATOM   5428 O O   . GLU A 1 749  ? 164.106 127.820 159.096 1.00 172.37 ? 767  GLU A O   1 
ATOM   5429 C CB  . GLU A 1 749  ? 161.084 127.872 159.298 1.00 180.00 ? 767  GLU A CB  1 
ATOM   5430 C CG  . GLU A 1 749  ? 160.045 128.273 160.339 1.00 183.85 ? 767  GLU A CG  1 
ATOM   5431 C CD  . GLU A 1 749  ? 160.489 129.455 161.177 1.00 184.49 ? 767  GLU A CD  1 
ATOM   5432 O OE1 . GLU A 1 749  ? 161.709 129.601 161.407 1.00 181.46 ? 767  GLU A OE1 1 
ATOM   5433 O OE2 . GLU A 1 749  ? 159.618 130.240 161.607 1.00 184.78 ? 767  GLU A OE2 1 
ATOM   5434 N N   . ILE A 1 750  ? 163.567 125.887 158.052 1.00 169.11 ? 768  ILE A N   1 
ATOM   5435 C CA  . ILE A 1 750  ? 164.731 125.849 157.171 1.00 163.50 ? 768  ILE A CA  1 
ATOM   5436 C C   . ILE A 1 750  ? 164.218 125.903 155.742 1.00 167.10 ? 768  ILE A C   1 
ATOM   5437 O O   . ILE A 1 750  ? 163.398 125.067 155.344 1.00 170.26 ? 768  ILE A O   1 
ATOM   5438 C CB  . ILE A 1 750  ? 165.585 124.592 157.401 1.00 164.38 ? 768  ILE A CB  1 
ATOM   5439 C CG1 . ILE A 1 750  ? 166.138 124.585 158.832 1.00 166.71 ? 768  ILE A CG1 1 
ATOM   5440 C CG2 . ILE A 1 750  ? 166.705 124.494 156.351 1.00 170.53 ? 768  ILE A CG2 1 
ATOM   5441 C CD1 . ILE A 1 750  ? 165.623 123.436 159.669 1.00 174.81 ? 768  ILE A CD1 1 
ATOM   5442 N N   . THR A 1 751  ? 164.704 126.877 154.974 1.00 168.68 ? 769  THR A N   1 
ATOM   5443 C CA  . THR A 1 751  ? 164.333 127.054 153.574 1.00 173.47 ? 769  THR A CA  1 
ATOM   5444 C C   . THR A 1 751  ? 165.511 126.615 152.714 1.00 175.17 ? 769  THR A C   1 
ATOM   5445 O O   . THR A 1 751  ? 166.551 127.283 152.687 1.00 173.53 ? 769  THR A O   1 
ATOM   5446 C CB  . THR A 1 751  ? 163.957 128.505 153.289 1.00 173.25 ? 769  THR A CB  1 
ATOM   5447 O OG1 . THR A 1 751  ? 163.101 128.992 154.329 1.00 179.35 ? 769  THR A OG1 1 
ATOM   5448 C CG2 . THR A 1 751  ? 163.240 128.620 151.951 1.00 179.88 ? 769  THR A CG2 1 
ATOM   5449 N N   . ILE A 1 752  ? 165.352 125.489 152.029 1.00 177.54 ? 770  ILE A N   1 
ATOM   5450 C CA  . ILE A 1 752  ? 166.339 125.013 151.068 1.00 175.50 ? 770  ILE A CA  1 
ATOM   5451 C C   . ILE A 1 752  ? 166.012 125.665 149.734 1.00 175.93 ? 770  ILE A C   1 
ATOM   5452 O O   . ILE A 1 752  ? 164.937 125.427 149.174 1.00 180.11 ? 770  ILE A O   1 
ATOM   5453 C CB  . ILE A 1 752  ? 166.320 123.481 150.949 1.00 176.64 ? 770  ILE A CB  1 
ATOM   5454 C CG1 . ILE A 1 752  ? 166.449 122.806 152.324 1.00 177.37 ? 770  ILE A CG1 1 
ATOM   5455 C CG2 . ILE A 1 752  ? 167.424 123.006 150.002 1.00 178.60 ? 770  ILE A CG2 1 
ATOM   5456 C CD1 . ILE A 1 752  ? 167.676 123.197 153.124 1.00 173.57 ? 770  ILE A CD1 1 
ATOM   5457 N N   . PHE A 1 753  ? 166.927 126.491 149.235 1.00 173.63 ? 771  PHE A N   1 
ATOM   5458 C CA  . PHE A 1 753  ? 166.759 127.196 147.972 1.00 174.70 ? 771  PHE A CA  1 
ATOM   5459 C C   . PHE A 1 753  ? 167.571 126.488 146.900 1.00 178.39 ? 771  PHE A C   1 
ATOM   5460 O O   . PHE A 1 753  ? 168.776 126.265 147.077 1.00 176.92 ? 771  PHE A O   1 
ATOM   5461 C CB  . PHE A 1 753  ? 167.211 128.650 148.089 1.00 167.36 ? 771  PHE A CB  1 
ATOM   5462 C CG  . PHE A 1 753  ? 166.096 129.616 148.358 1.00 169.57 ? 771  PHE A CG  1 
ATOM   5463 C CD1 . PHE A 1 753  ? 165.244 130.009 147.341 1.00 175.70 ? 771  PHE A CD1 1 
ATOM   5464 C CD2 . PHE A 1 753  ? 165.905 130.138 149.625 1.00 167.34 ? 771  PHE A CD2 1 
ATOM   5465 C CE1 . PHE A 1 753  ? 164.219 130.900 147.584 1.00 176.20 ? 771  PHE A CE1 1 
ATOM   5466 C CE2 . PHE A 1 753  ? 164.881 131.030 149.874 1.00 171.84 ? 771  PHE A CE2 1 
ATOM   5467 C CZ  . PHE A 1 753  ? 164.037 131.412 148.852 1.00 175.88 ? 771  PHE A CZ  1 
ATOM   5468 N N   . ASN A 1 754  ? 166.908 126.137 145.798 1.00 184.82 ? 772  ASN A N   1 
ATOM   5469 C CA  . ASN A 1 754  ? 167.530 125.472 144.662 1.00 188.15 ? 772  ASN A CA  1 
ATOM   5470 C C   . ASN A 1 754  ? 167.340 126.331 143.423 1.00 188.06 ? 772  ASN A C   1 
ATOM   5471 O O   . ASN A 1 754  ? 166.214 126.729 143.107 1.00 188.79 ? 772  ASN A O   1 
ATOM   5472 C CB  . ASN A 1 754  ? 166.925 124.086 144.437 1.00 194.61 ? 772  ASN A CB  1 
ATOM   5473 C CG  . ASN A 1 754  ? 167.563 123.359 143.274 1.00 198.62 ? 772  ASN A CG  1 
ATOM   5474 O OD1 . ASN A 1 754  ? 168.778 123.411 143.092 1.00 195.78 ? 772  ASN A OD1 1 
ATOM   5475 N ND2 . ASN A 1 754  ? 166.746 122.680 142.477 1.00 201.73 ? 772  ASN A ND2 1 
ATOM   5476 N N   . TYR A 1 755  ? 168.445 126.617 142.731 1.00 186.07 ? 773  TYR A N   1 
ATOM   5477 C CA  . TYR A 1 755  ? 168.440 127.377 141.486 1.00 189.87 ? 773  TYR A CA  1 
ATOM   5478 C C   . TYR A 1 755  ? 169.012 126.557 140.329 1.00 195.82 ? 773  TYR A C   1 
ATOM   5479 O O   . TYR A 1 755  ? 169.465 127.114 139.326 1.00 197.94 ? 773  TYR A O   1 
ATOM   5480 C CB  . TYR A 1 755  ? 169.202 128.690 141.674 1.00 183.65 ? 773  TYR A CB  1 
ATOM   5481 C CG  . TYR A 1 755  ? 168.379 129.764 142.348 1.00 181.53 ? 773  TYR A CG  1 
ATOM   5482 C CD1 . TYR A 1 755  ? 167.579 130.620 141.604 1.00 182.31 ? 773  TYR A CD1 1 
ATOM   5483 C CD2 . TYR A 1 755  ? 168.394 129.916 143.726 1.00 177.16 ? 773  TYR A CD2 1 
ATOM   5484 C CE1 . TYR A 1 755  ? 166.822 131.603 142.214 1.00 175.94 ? 773  TYR A CE1 1 
ATOM   5485 C CE2 . TYR A 1 755  ? 167.641 130.895 144.346 1.00 177.93 ? 773  TYR A CE2 1 
ATOM   5486 C CZ  . TYR A 1 755  ? 166.856 131.735 143.585 1.00 175.15 ? 773  TYR A CZ  1 
ATOM   5487 O OH  . TYR A 1 755  ? 166.104 132.712 144.196 1.00 164.27 ? 773  TYR A OH  1 
ATOM   5488 N N   . LEU A 1 756  ? 168.977 125.229 140.445 1.00 197.69 ? 774  LEU A N   1 
ATOM   5489 C CA  . LEU A 1 756  ? 169.345 124.354 139.343 1.00 201.17 ? 774  LEU A CA  1 
ATOM   5490 C C   . LEU A 1 756  ? 168.144 124.181 138.414 1.00 208.43 ? 774  LEU A C   1 
ATOM   5491 O O   . LEU A 1 756  ? 167.032 124.629 138.704 1.00 208.81 ? 774  LEU A O   1 
ATOM   5492 C CB  . LEU A 1 756  ? 169.847 123.008 139.871 1.00 198.86 ? 774  LEU A CB  1 
ATOM   5493 C CG  . LEU A 1 756  ? 171.366 122.821 139.946 1.00 192.69 ? 774  LEU A CG  1 
ATOM   5494 C CD1 . LEU A 1 756  ? 171.979 122.678 138.557 1.00 192.06 ? 774  LEU A CD1 1 
ATOM   5495 C CD2 . LEU A 1 756  ? 172.016 123.968 140.705 1.00 183.95 ? 774  LEU A CD2 1 
ATOM   5496 N N   . LYS A 1 757  ? 168.365 123.517 137.283 1.00 212.82 ? 775  LYS A N   1 
ATOM   5497 C CA  . LYS A 1 757  ? 167.335 123.347 136.268 1.00 217.35 ? 775  LYS A CA  1 
ATOM   5498 C C   . LYS A 1 757  ? 166.404 122.170 136.539 1.00 219.23 ? 775  LYS A C   1 
ATOM   5499 O O   . LYS A 1 757  ? 165.521 121.907 135.715 1.00 220.35 ? 775  LYS A O   1 
ATOM   5500 C CB  . LYS A 1 757  ? 167.983 123.170 134.889 1.00 217.24 ? 775  LYS A CB  1 
ATOM   5501 C CG  . LYS A 1 757  ? 169.022 124.234 134.507 1.00 213.66 ? 775  LYS A CG  1 
ATOM   5502 C CD  . LYS A 1 757  ? 168.491 125.670 134.555 1.00 213.17 ? 775  LYS A CD  1 
ATOM   5503 C CE  . LYS A 1 757  ? 167.411 125.919 133.511 1.00 215.87 ? 775  LYS A CE  1 
ATOM   5504 N NZ  . LYS A 1 757  ? 166.973 127.342 133.492 1.00 216.20 ? 775  LYS A NZ  1 
ATOM   5505 N N   . ASP A 1 758  ? 166.575 121.457 137.655 1.00 218.35 ? 776  ASP A N   1 
ATOM   5506 C CA  . ASP A 1 758  ? 165.761 120.296 137.984 1.00 217.31 ? 776  ASP A CA  1 
ATOM   5507 C C   . ASP A 1 758  ? 165.374 120.331 139.454 1.00 214.74 ? 776  ASP A C   1 
ATOM   5508 O O   . ASP A 1 758  ? 166.147 120.777 140.307 1.00 211.36 ? 776  ASP A O   1 
ATOM   5509 C CB  . ASP A 1 758  ? 166.506 118.990 137.683 1.00 218.77 ? 776  ASP A CB  1 
ATOM   5510 C CG  . ASP A 1 758  ? 166.937 118.886 136.236 1.00 225.10 ? 776  ASP A CG  1 
ATOM   5511 O OD1 . ASP A 1 758  ? 166.095 119.127 135.346 1.00 229.02 ? 776  ASP A OD1 1 
ATOM   5512 O OD2 . ASP A 1 758  ? 168.118 118.565 135.988 1.00 226.29 ? 776  ASP A OD2 1 
ATOM   5513 N N   . ALA A 1 759  ? 164.163 119.859 139.741 1.00 215.27 ? 777  ALA A N   1 
ATOM   5514 C CA  . ALA A 1 759  ? 163.735 119.698 141.122 1.00 213.92 ? 777  ALA A CA  1 
ATOM   5515 C C   . ALA A 1 759  ? 164.525 118.566 141.766 1.00 214.79 ? 777  ALA A C   1 
ATOM   5516 O O   . ALA A 1 759  ? 164.703 117.504 141.161 1.00 214.38 ? 777  ALA A O   1 
ATOM   5517 C CB  . ALA A 1 759  ? 162.237 119.409 141.187 1.00 210.50 ? 777  ALA A CB  1 
ATOM   5518 N N   . THR A 1 760  ? 164.990 118.791 142.995 1.00 212.49 ? 778  THR A N   1 
ATOM   5519 C CA  . THR A 1 760  ? 165.941 117.905 143.656 1.00 211.29 ? 778  THR A CA  1 
ATOM   5520 C C   . THR A 1 760  ? 165.383 117.402 144.979 1.00 210.27 ? 778  THR A C   1 
ATOM   5521 O O   . THR A 1 760  ? 164.772 118.160 145.737 1.00 209.65 ? 778  THR A O   1 
ATOM   5522 C CB  . THR A 1 760  ? 167.271 118.621 143.905 1.00 213.79 ? 778  THR A CB  1 
ATOM   5523 O OG1 . THR A 1 760  ? 167.024 119.896 144.511 1.00 216.92 ? 778  THR A OG1 1 
ATOM   5524 C CG2 . THR A 1 760  ? 168.022 118.818 142.598 1.00 211.09 ? 778  THR A CG2 1 
ATOM   5525 N N   . GLU A 1 761  ? 165.604 116.117 145.249 1.00 208.89 ? 779  GLU A N   1 
ATOM   5526 C CA  . GLU A 1 761  ? 165.266 115.515 146.534 1.00 207.90 ? 779  GLU A CA  1 
ATOM   5527 C C   . GLU A 1 761  ? 166.426 115.767 147.489 1.00 207.93 ? 779  GLU A C   1 
ATOM   5528 O O   . GLU A 1 761  ? 167.497 115.167 147.347 1.00 207.67 ? 779  GLU A O   1 
ATOM   5529 C CB  . GLU A 1 761  ? 164.991 114.021 146.376 1.00 207.18 ? 779  GLU A CB  1 
ATOM   5530 C CG  . GLU A 1 761  ? 164.345 113.370 147.595 1.00 206.21 ? 779  GLU A CG  1 
ATOM   5531 C CD  . GLU A 1 761  ? 162.844 113.587 147.658 1.00 210.48 ? 779  GLU A CD  1 
ATOM   5532 O OE1 . GLU A 1 761  ? 162.320 114.400 146.869 1.00 209.53 ? 779  GLU A OE1 1 
ATOM   5533 O OE2 . GLU A 1 761  ? 162.187 112.941 148.501 1.00 215.99 ? 779  GLU A OE2 1 
ATOM   5534 N N   . VAL A 1 762  ? 166.208 116.648 148.462 1.00 207.28 ? 780  VAL A N   1 
ATOM   5535 C CA  . VAL A 1 762  ? 167.241 117.099 149.389 1.00 206.21 ? 780  VAL A CA  1 
ATOM   5536 C C   . VAL A 1 762  ? 166.934 116.543 150.771 1.00 205.67 ? 780  VAL A C   1 
ATOM   5537 O O   . VAL A 1 762  ? 165.781 116.578 151.226 1.00 205.70 ? 780  VAL A O   1 
ATOM   5538 C CB  . VAL A 1 762  ? 167.339 118.635 149.425 1.00 202.69 ? 780  VAL A CB  1 
ATOM   5539 C CG1 . VAL A 1 762  ? 168.522 119.073 150.290 1.00 197.12 ? 780  VAL A CG1 1 
ATOM   5540 C CG2 . VAL A 1 762  ? 167.469 119.196 148.009 1.00 203.55 ? 780  VAL A CG2 1 
ATOM   5541 N N   . LYS A 1 763  ? 167.970 116.033 151.434 1.00 203.70 ? 781  LYS A N   1 
ATOM   5542 C CA  . LYS A 1 763  ? 167.888 115.548 152.804 1.00 204.20 ? 781  LYS A CA  1 
ATOM   5543 C C   . LYS A 1 763  ? 168.495 116.600 153.723 1.00 202.77 ? 781  LYS A C   1 
ATOM   5544 O O   . LYS A 1 763  ? 169.655 116.990 153.546 1.00 198.31 ? 781  LYS A O   1 
ATOM   5545 C CB  . LYS A 1 763  ? 168.620 114.214 152.946 1.00 203.95 ? 781  LYS A CB  1 
ATOM   5546 C CG  . LYS A 1 763  ? 168.314 113.465 154.234 1.00 208.53 ? 781  LYS A CG  1 
ATOM   5547 C CD  . LYS A 1 763  ? 169.181 112.221 154.375 1.00 209.13 ? 781  LYS A CD  1 
ATOM   5548 C CE  . LYS A 1 763  ? 168.668 111.077 153.515 1.00 204.98 ? 781  LYS A CE  1 
ATOM   5549 N NZ  . LYS A 1 763  ? 169.454 109.828 153.722 1.00 198.94 ? 781  LYS A NZ  1 
ATOM   5550 N N   . VAL A 1 764  ? 167.710 117.056 154.695 1.00 204.76 ? 782  VAL A N   1 
ATOM   5551 C CA  . VAL A 1 764  ? 168.121 118.082 155.646 1.00 200.35 ? 782  VAL A CA  1 
ATOM   5552 C C   . VAL A 1 764  ? 168.403 117.398 156.975 1.00 197.87 ? 782  VAL A C   1 
ATOM   5553 O O   . VAL A 1 764  ? 167.511 116.771 157.557 1.00 200.75 ? 782  VAL A O   1 
ATOM   5554 C CB  . VAL A 1 764  ? 167.041 119.165 155.801 1.00 200.32 ? 782  VAL A CB  1 
ATOM   5555 C CG1 . VAL A 1 764  ? 167.424 120.143 156.906 1.00 196.77 ? 782  VAL A CG1 1 
ATOM   5556 C CG2 . VAL A 1 764  ? 166.822 119.891 154.478 1.00 199.81 ? 782  VAL A CG2 1 
ATOM   5557 N N   . ILE A 1 765  ? 169.633 117.538 157.461 1.00 190.65 ? 783  ILE A N   1 
ATOM   5558 C CA  . ILE A 1 765  ? 170.105 116.879 158.673 1.00 194.75 ? 783  ILE A CA  1 
ATOM   5559 C C   . ILE A 1 765  ? 170.335 117.953 159.726 1.00 192.19 ? 783  ILE A C   1 
ATOM   5560 O O   . ILE A 1 765  ? 171.036 118.943 159.473 1.00 184.08 ? 783  ILE A O   1 
ATOM   5561 C CB  . ILE A 1 765  ? 171.392 116.076 158.421 1.00 196.31 ? 783  ILE A CB  1 
ATOM   5562 C CG1 . ILE A 1 765  ? 171.128 114.904 157.466 1.00 201.55 ? 783  ILE A CG1 1 
ATOM   5563 C CG2 . ILE A 1 765  ? 171.964 115.564 159.741 1.00 203.96 ? 783  ILE A CG2 1 
ATOM   5564 C CD1 . ILE A 1 765  ? 172.375 114.372 156.785 1.00 200.97 ? 783  ILE A CD1 1 
ATOM   5565 N N   . ILE A 1 766  ? 169.735 117.754 160.897 1.00 200.39 ? 784  ILE A N   1 
ATOM   5566 C CA  . ILE A 1 766  ? 169.957 118.590 162.071 1.00 199.82 ? 784  ILE A CA  1 
ATOM   5567 C C   . ILE A 1 766  ? 170.911 117.835 162.984 1.00 203.23 ? 784  ILE A C   1 
ATOM   5568 O O   . ILE A 1 766  ? 170.586 116.743 163.465 1.00 210.07 ? 784  ILE A O   1 
ATOM   5569 C CB  . ILE A 1 766  ? 168.640 118.913 162.798 1.00 202.11 ? 784  ILE A CB  1 
ATOM   5570 C CG1 . ILE A 1 766  ? 167.551 119.403 161.826 1.00 198.08 ? 784  ILE A CG1 1 
ATOM   5571 C CG2 . ILE A 1 766  ? 168.878 119.940 163.903 1.00 195.36 ? 784  ILE A CG2 1 
ATOM   5572 C CD1 . ILE A 1 766  ? 167.900 120.658 161.041 1.00 192.18 ? 784  ILE A CD1 1 
ATOM   5573 N N   . GLU A 1 767  ? 172.086 118.408 163.225 1.00 201.26 ? 785  GLU A N   1 
ATOM   5574 C CA  . GLU A 1 767  ? 173.092 117.729 164.031 1.00 201.76 ? 785  GLU A CA  1 
ATOM   5575 C C   . GLU A 1 767  ? 172.632 117.640 165.480 1.00 200.58 ? 785  GLU A C   1 
ATOM   5576 O O   . GLU A 1 767  ? 172.085 118.600 166.030 1.00 198.29 ? 785  GLU A O   1 
ATOM   5577 C CB  . GLU A 1 767  ? 174.428 118.464 163.947 1.00 195.35 ? 785  GLU A CB  1 
ATOM   5578 C CG  . GLU A 1 767  ? 175.287 118.055 162.760 1.00 198.47 ? 785  GLU A CG  1 
ATOM   5579 C CD  . GLU A 1 767  ? 174.670 118.437 161.427 1.00 198.81 ? 785  GLU A CD  1 
ATOM   5580 O OE1 . GLU A 1 767  ? 173.892 119.413 161.386 1.00 195.76 ? 785  GLU A OE1 1 
ATOM   5581 O OE2 . GLU A 1 767  ? 174.963 117.760 160.420 1.00 199.94 ? 785  GLU A OE2 1 
ATOM   5582 N N   . LYS A 1 768  ? 172.857 116.484 166.097 1.00 199.52 ? 786  LYS A N   1 
ATOM   5583 C CA  . LYS A 1 768  ? 172.460 116.292 167.484 1.00 198.11 ? 786  LYS A CA  1 
ATOM   5584 C C   . LYS A 1 768  ? 173.401 117.040 168.417 1.00 193.95 ? 786  LYS A C   1 
ATOM   5585 O O   . LYS A 1 768  ? 174.606 117.139 168.165 1.00 190.79 ? 786  LYS A O   1 
ATOM   5586 C CB  . LYS A 1 768  ? 172.451 114.805 167.837 1.00 199.31 ? 786  LYS A CB  1 
ATOM   5587 C CG  . LYS A 1 768  ? 171.153 114.095 167.476 1.00 207.89 ? 786  LYS A CG  1 
ATOM   5588 C CD  . LYS A 1 768  ? 170.096 114.219 168.579 1.00 211.55 ? 786  LYS A CD  1 
ATOM   5589 C CE  . LYS A 1 768  ? 170.365 113.327 169.796 1.00 214.81 ? 786  LYS A CE  1 
ATOM   5590 N NZ  . LYS A 1 768  ? 170.541 111.884 169.465 1.00 232.84 ? 786  LYS A NZ  1 
ATOM   5591 N N   . SER A 1 769  ? 172.841 117.574 169.499 1.00 191.66 ? 787  SER A N   1 
ATOM   5592 C CA  . SER A 1 769  ? 173.627 118.257 170.514 1.00 187.30 ? 787  SER A CA  1 
ATOM   5593 C C   . SER A 1 769  ? 172.915 118.137 171.851 1.00 185.39 ? 787  SER A C   1 
ATOM   5594 O O   . SER A 1 769  ? 171.692 117.986 171.916 1.00 182.76 ? 787  SER A O   1 
ATOM   5595 C CB  . SER A 1 769  ? 173.851 119.731 170.158 1.00 181.41 ? 787  SER A CB  1 
ATOM   5596 O OG  . SER A 1 769  ? 174.271 120.468 171.293 1.00 179.88 ? 787  SER A OG  1 
ATOM   5597 N N   . ASP A 1 770  ? 173.702 118.208 172.924 1.00 187.84 ? 788  ASP A N   1 
ATOM   5598 C CA  . ASP A 1 770  ? 173.145 118.125 174.269 1.00 188.05 ? 788  ASP A CA  1 
ATOM   5599 C C   . ASP A 1 770  ? 172.423 119.398 174.688 1.00 185.60 ? 788  ASP A C   1 
ATOM   5600 O O   . ASP A 1 770  ? 171.583 119.347 175.592 1.00 187.09 ? 788  ASP A O   1 
ATOM   5601 C CB  . ASP A 1 770  ? 174.250 117.819 175.286 1.00 189.28 ? 788  ASP A CB  1 
ATOM   5602 C CG  . ASP A 1 770  ? 175.356 118.861 175.286 1.00 188.27 ? 788  ASP A CG  1 
ATOM   5603 O OD1 . ASP A 1 770  ? 175.380 119.707 174.367 1.00 187.57 ? 788  ASP A OD1 1 
ATOM   5604 O OD2 . ASP A 1 770  ? 176.201 118.832 176.205 1.00 188.30 ? 788  ASP A OD2 1 
ATOM   5605 N N   . LYS A 1 771  ? 172.725 120.534 174.056 1.00 181.36 ? 789  LYS A N   1 
ATOM   5606 C CA  . LYS A 1 771  ? 172.169 121.807 174.495 1.00 177.32 ? 789  LYS A CA  1 
ATOM   5607 C C   . LYS A 1 771  ? 170.702 121.982 174.123 1.00 177.11 ? 789  LYS A C   1 
ATOM   5608 O O   . LYS A 1 771  ? 170.017 122.796 174.753 1.00 175.18 ? 789  LYS A O   1 
ATOM   5609 C CB  . LYS A 1 771  ? 172.988 122.957 173.909 1.00 171.74 ? 789  LYS A CB  1 
ATOM   5610 C CG  . LYS A 1 771  ? 174.440 122.961 174.360 1.00 168.08 ? 789  LYS A CG  1 
ATOM   5611 C CD  . LYS A 1 771  ? 175.062 124.342 174.253 1.00 165.91 ? 789  LYS A CD  1 
ATOM   5612 C CE  . LYS A 1 771  ? 176.464 124.362 174.835 1.00 164.97 ? 789  LYS A CE  1 
ATOM   5613 N NZ  . LYS A 1 771  ? 177.065 125.723 174.800 1.00 161.02 ? 789  LYS A NZ  1 
ATOM   5614 N N   . PHE A 1 772  ? 170.207 121.249 173.128 1.00 178.63 ? 790  PHE A N   1 
ATOM   5615 C CA  . PHE A 1 772  ? 168.810 121.336 172.728 1.00 176.94 ? 790  PHE A CA  1 
ATOM   5616 C C   . PHE A 1 772  ? 168.363 119.974 172.222 1.00 179.40 ? 790  PHE A C   1 
ATOM   5617 O O   . PHE A 1 772  ? 169.184 119.102 171.927 1.00 180.61 ? 790  PHE A O   1 
ATOM   5618 C CB  . PHE A 1 772  ? 168.591 122.412 171.656 1.00 172.00 ? 790  PHE A CB  1 
ATOM   5619 C CG  . PHE A 1 772  ? 169.234 122.097 170.336 1.00 173.25 ? 790  PHE A CG  1 
ATOM   5620 C CD1 . PHE A 1 772  ? 170.573 122.368 170.120 1.00 175.06 ? 790  PHE A CD1 1 
ATOM   5621 C CD2 . PHE A 1 772  ? 168.494 121.544 169.304 1.00 173.87 ? 790  PHE A CD2 1 
ATOM   5622 C CE1 . PHE A 1 772  ? 171.164 122.084 168.905 1.00 176.21 ? 790  PHE A CE1 1 
ATOM   5623 C CE2 . PHE A 1 772  ? 169.080 121.257 168.089 1.00 176.53 ? 790  PHE A CE2 1 
ATOM   5624 C CZ  . PHE A 1 772  ? 170.417 121.528 167.890 1.00 176.51 ? 790  PHE A CZ  1 
ATOM   5625 N N   . ASP A 1 773  ? 167.043 119.806 172.123 1.00 179.44 ? 791  ASP A N   1 
ATOM   5626 C CA  . ASP A 1 773  ? 166.430 118.542 171.739 1.00 182.54 ? 791  ASP A CA  1 
ATOM   5627 C C   . ASP A 1 773  ? 165.432 118.763 170.613 1.00 182.67 ? 791  ASP A C   1 
ATOM   5628 O O   . ASP A 1 773  ? 164.886 119.858 170.448 1.00 180.32 ? 791  ASP A O   1 
ATOM   5629 C CB  . ASP A 1 773  ? 165.721 117.887 172.929 1.00 189.41 ? 791  ASP A CB  1 
ATOM   5630 C CG  . ASP A 1 773  ? 166.550 117.931 174.195 1.00 195.37 ? 791  ASP A CG  1 
ATOM   5631 O OD1 . ASP A 1 773  ? 167.739 117.553 174.141 1.00 195.54 ? 791  ASP A OD1 1 
ATOM   5632 O OD2 . ASP A 1 773  ? 166.014 118.346 175.243 1.00 196.44 ? 791  ASP A OD2 1 
ATOM   5633 N N   . ILE A 1 774  ? 165.201 117.697 169.850 1.00 187.26 ? 792  ILE A N   1 
ATOM   5634 C CA  . ILE A 1 774  ? 164.222 117.663 168.767 1.00 195.56 ? 792  ILE A CA  1 
ATOM   5635 C C   . ILE A 1 774  ? 163.152 116.659 169.175 1.00 204.48 ? 792  ILE A C   1 
ATOM   5636 O O   . ILE A 1 774  ? 163.467 115.528 169.563 1.00 209.73 ? 792  ILE A O   1 
ATOM   5637 C CB  . ILE A 1 774  ? 164.878 117.306 167.413 1.00 202.45 ? 792  ILE A CB  1 
ATOM   5638 C CG1 . ILE A 1 774  ? 163.846 117.016 166.307 1.00 206.88 ? 792  ILE A CG1 1 
ATOM   5639 C CG2 . ILE A 1 774  ? 165.833 116.111 167.537 1.00 210.37 ? 792  ILE A CG2 1 
ATOM   5640 C CD1 . ILE A 1 774  ? 162.895 118.152 166.015 1.00 192.18 ? 792  ILE A CD1 1 
ATOM   5641 N N   . LEU A 1 775  ? 161.888 117.079 169.106 1.00 207.28 ? 793  LEU A N   1 
ATOM   5642 C CA  . LEU A 1 775  ? 160.809 116.296 169.698 1.00 213.20 ? 793  LEU A CA  1 
ATOM   5643 C C   . LEU A 1 775  ? 160.456 115.080 168.849 1.00 222.18 ? 793  LEU A C   1 
ATOM   5644 O O   . LEU A 1 775  ? 160.600 113.936 169.294 1.00 226.24 ? 793  LEU A O   1 
ATOM   5645 C CB  . LEU A 1 775  ? 159.574 117.180 169.894 1.00 208.99 ? 793  LEU A CB  1 
ATOM   5646 C CG  . LEU A 1 775  ? 159.753 118.509 170.629 1.00 203.81 ? 793  LEU A CG  1 
ATOM   5647 C CD1 . LEU A 1 775  ? 158.399 119.174 170.788 1.00 204.84 ? 793  LEU A CD1 1 
ATOM   5648 C CD2 . LEU A 1 775  ? 160.424 118.329 171.982 1.00 197.20 ? 793  LEU A CD2 1 
ATOM   5649 N N   . MET A 1 776  ? 159.996 115.307 167.623 1.00 227.86 ? 794  MET A N   1 
ATOM   5650 C CA  . MET A 1 776  ? 159.483 114.223 166.797 1.00 242.01 ? 794  MET A CA  1 
ATOM   5651 C C   . MET A 1 776  ? 160.628 113.404 166.219 1.00 249.53 ? 794  MET A C   1 
ATOM   5652 O O   . MET A 1 776  ? 161.633 113.952 165.759 1.00 245.50 ? 794  MET A O   1 
ATOM   5653 C CB  . MET A 1 776  ? 158.609 114.785 165.671 1.00 239.20 ? 794  MET A CB  1 
ATOM   5654 C CG  . MET A 1 776  ? 158.160 113.792 164.588 1.00 247.18 ? 794  MET A CG  1 
ATOM   5655 S SD  . MET A 1 776  ? 157.750 112.071 165.002 1.00 250.70 ? 794  MET A SD  1 
ATOM   5656 C CE  . MET A 1 776  ? 156.634 112.188 166.411 1.00 238.90 ? 794  MET A CE  1 
ATOM   5657 N N   . THR A 1 777  ? 160.472 112.084 166.244 1.00 257.14 ? 795  THR A N   1 
ATOM   5658 C CA  . THR A 1 777  ? 161.506 111.203 165.720 1.00 263.44 ? 795  THR A CA  1 
ATOM   5659 C C   . THR A 1 777  ? 161.593 111.317 164.199 1.00 267.90 ? 795  THR A C   1 
ATOM   5660 O O   . THR A 1 777  ? 160.687 111.822 163.530 1.00 267.57 ? 795  THR A O   1 
ATOM   5661 C CB  . THR A 1 777  ? 161.257 109.742 166.128 1.00 265.70 ? 795  THR A CB  1 
ATOM   5662 O OG1 . THR A 1 777  ? 162.270 108.906 165.553 1.00 270.55 ? 795  THR A OG1 1 
ATOM   5663 C CG2 . THR A 1 777  ? 159.875 109.230 165.681 1.00 261.36 ? 795  THR A CG2 1 
ATOM   5664 N N   . SER A 1 778  ? 162.709 110.833 163.661 1.00 271.87 ? 796  SER A N   1 
ATOM   5665 C CA  . SER A 1 778  ? 163.025 110.899 162.245 1.00 273.81 ? 796  SER A CA  1 
ATOM   5666 C C   . SER A 1 778  ? 162.850 109.519 161.617 1.00 284.48 ? 796  SER A C   1 
ATOM   5667 O O   . SER A 1 778  ? 162.413 108.564 162.266 1.00 286.94 ? 796  SER A O   1 
ATOM   5668 C CB  . SER A 1 778  ? 164.446 111.434 162.058 1.00 262.93 ? 796  SER A CB  1 
ATOM   5669 O OG  . SER A 1 778  ? 164.785 111.513 160.685 1.00 257.26 ? 796  SER A OG  1 
ATOM   5670 N N   . ASN A 1 779  ? 163.186 109.412 160.329 1.00 288.59 ? 797  ASN A N   1 
ATOM   5671 C CA  . ASN A 1 779  ? 163.076 108.127 159.643 1.00 293.37 ? 797  ASN A CA  1 
ATOM   5672 C C   . ASN A 1 779  ? 164.022 107.094 160.245 1.00 297.68 ? 797  ASN A C   1 
ATOM   5673 O O   . ASN A 1 779  ? 163.645 105.931 160.428 1.00 302.06 ? 797  ASN A O   1 
ATOM   5674 C CB  . ASN A 1 779  ? 163.350 108.291 158.145 1.00 291.14 ? 797  ASN A CB  1 
ATOM   5675 C CG  . ASN A 1 779  ? 164.675 108.978 157.854 1.00 282.20 ? 797  ASN A CG  1 
ATOM   5676 O OD1 . ASN A 1 779  ? 165.433 109.306 158.767 1.00 280.52 ? 797  ASN A OD1 1 
ATOM   5677 N ND2 . ASN A 1 779  ? 164.960 109.193 156.575 1.00 274.63 ? 797  ASN A ND2 1 
ATOM   5678 N N   . GLU A 1 780  ? 165.249 107.498 160.564 1.00 298.19 ? 798  GLU A N   1 
ATOM   5679 C CA  . GLU A 1 780  ? 166.220 106.584 161.139 1.00 301.21 ? 798  GLU A CA  1 
ATOM   5680 C C   . GLU A 1 780  ? 165.952 106.380 162.629 1.00 305.09 ? 798  GLU A C   1 
ATOM   5681 O O   . GLU A 1 780  ? 165.305 107.198 163.289 1.00 300.76 ? 798  GLU A O   1 
ATOM   5682 C CB  . GLU A 1 780  ? 167.644 107.104 160.912 1.00 297.06 ? 798  GLU A CB  1 
ATOM   5683 C CG  . GLU A 1 780  ? 168.016 108.368 161.691 1.00 287.50 ? 798  GLU A CG  1 
ATOM   5684 C CD  . GLU A 1 780  ? 169.402 108.877 161.346 1.00 276.16 ? 798  GLU A CD  1 
ATOM   5685 O OE1 . GLU A 1 780  ? 169.992 108.387 160.360 1.00 267.14 ? 798  GLU A OE1 1 
ATOM   5686 O OE2 . GLU A 1 780  ? 169.906 109.763 162.066 1.00 272.25 ? 798  GLU A OE2 1 
ATOM   5687 N N   . ILE A 1 781  ? 166.470 105.266 163.149 1.00 309.58 ? 799  ILE A N   1 
ATOM   5688 C CA  . ILE A 1 781  ? 166.352 104.918 164.563 1.00 310.36 ? 799  ILE A CA  1 
ATOM   5689 C C   . ILE A 1 781  ? 167.649 105.131 165.332 1.00 309.67 ? 799  ILE A C   1 
ATOM   5690 O O   . ILE A 1 781  ? 167.618 105.137 166.574 1.00 311.08 ? 799  ILE A O   1 
ATOM   5691 C CB  . ILE A 1 781  ? 165.856 103.464 164.741 1.00 311.39 ? 799  ILE A CB  1 
ATOM   5692 C CG1 . ILE A 1 781  ? 165.048 103.320 166.036 1.00 306.59 ? 799  ILE A CG1 1 
ATOM   5693 C CG2 . ILE A 1 781  ? 167.010 102.447 164.690 1.00 311.66 ? 799  ILE A CG2 1 
ATOM   5694 C CD1 . ILE A 1 781  ? 163.611 103.793 165.924 1.00 299.72 ? 799  ILE A CD1 1 
ATOM   5695 N N   . ASN A 1 782  ? 168.784 105.303 164.647 1.00 307.99 ? 800  ASN A N   1 
ATOM   5696 C CA  . ASN A 1 782  ? 170.043 105.539 165.347 1.00 306.49 ? 800  ASN A CA  1 
ATOM   5697 C C   . ASN A 1 782  ? 170.007 106.850 166.122 1.00 304.38 ? 800  ASN A C   1 
ATOM   5698 O O   . ASN A 1 782  ? 170.501 106.920 167.254 1.00 304.98 ? 800  ASN A O   1 
ATOM   5699 C CB  . ASN A 1 782  ? 171.202 105.539 164.351 1.00 301.37 ? 800  ASN A CB  1 
ATOM   5700 C CG  . ASN A 1 782  ? 172.542 105.784 165.016 1.00 298.89 ? 800  ASN A CG  1 
ATOM   5701 O OD1 . ASN A 1 782  ? 172.997 106.923 165.119 1.00 296.40 ? 800  ASN A OD1 1 
ATOM   5702 N ND2 . ASN A 1 782  ? 173.181 104.713 165.472 1.00 298.12 ? 800  ASN A ND2 1 
ATOM   5703 N N   . ALA A 1 783  ? 169.434 107.895 165.528 1.00 301.28 ? 801  ALA A N   1 
ATOM   5704 C CA  . ALA A 1 783  ? 169.287 109.200 166.160 1.00 290.97 ? 801  ALA A CA  1 
ATOM   5705 C C   . ALA A 1 783  ? 167.872 109.702 165.922 1.00 286.07 ? 801  ALA A C   1 
ATOM   5706 O O   . ALA A 1 783  ? 167.372 109.645 164.793 1.00 285.71 ? 801  ALA A O   1 
ATOM   5707 C CB  . ALA A 1 783  ? 170.311 110.199 165.613 1.00 274.84 ? 801  ALA A CB  1 
ATOM   5708 N N   . THR A 1 784  ? 167.232 110.193 166.981 1.00 284.25 ? 802  THR A N   1 
ATOM   5709 C CA  . THR A 1 784  ? 165.846 110.643 166.908 1.00 278.16 ? 802  THR A CA  1 
ATOM   5710 C C   . THR A 1 784  ? 165.797 112.096 166.450 1.00 268.36 ? 802  THR A C   1 
ATOM   5711 O O   . THR A 1 784  ? 166.582 112.930 166.912 1.00 262.22 ? 802  THR A O   1 
ATOM   5712 C CB  . THR A 1 784  ? 165.126 110.480 168.255 1.00 276.81 ? 802  THR A CB  1 
ATOM   5713 O OG1 . THR A 1 784  ? 163.788 110.983 168.143 1.00 268.58 ? 802  THR A OG1 1 
ATOM   5714 C CG2 . THR A 1 784  ? 165.836 111.215 169.410 1.00 270.34 ? 802  THR A CG2 1 
ATOM   5715 N N   . GLY A 1 785  ? 164.878 112.387 165.533 1.00 261.88 ? 803  GLY A N   1 
ATOM   5716 C CA  . GLY A 1 785  ? 164.739 113.727 164.996 1.00 250.73 ? 803  GLY A CA  1 
ATOM   5717 C C   . GLY A 1 785  ? 165.962 114.224 164.263 1.00 242.75 ? 803  GLY A C   1 
ATOM   5718 O O   . GLY A 1 785  ? 166.168 115.437 164.161 1.00 233.09 ? 803  GLY A O   1 
ATOM   5719 N N   . HIS A 1 786  ? 166.781 113.314 163.737 1.00 243.97 ? 804  HIS A N   1 
ATOM   5720 C CA  . HIS A 1 786  ? 168.063 113.705 163.169 1.00 238.19 ? 804  HIS A CA  1 
ATOM   5721 C C   . HIS A 1 786  ? 167.922 114.354 161.799 1.00 224.73 ? 804  HIS A C   1 
ATOM   5722 O O   . HIS A 1 786  ? 168.704 115.253 161.470 1.00 218.38 ? 804  HIS A O   1 
ATOM   5723 C CB  . HIS A 1 786  ? 168.980 112.483 163.067 1.00 246.75 ? 804  HIS A CB  1 
ATOM   5724 C CG  . HIS A 1 786  ? 170.441 112.802 163.174 1.00 240.18 ? 804  HIS A CG  1 
ATOM   5725 N ND1 . HIS A 1 786  ? 170.956 113.662 164.122 1.00 225.64 ? 804  HIS A ND1 1 
ATOM   5726 C CD2 . HIS A 1 786  ? 171.500 112.369 162.448 1.00 238.31 ? 804  HIS A CD2 1 
ATOM   5727 C CE1 . HIS A 1 786  ? 172.266 113.746 163.974 1.00 220.92 ? 804  HIS A CE1 1 
ATOM   5728 N NE2 . HIS A 1 786  ? 172.621 112.971 162.965 1.00 227.45 ? 804  HIS A NE2 1 
ATOM   5729 N N   . GLN A 1 787  ? 166.952 113.924 160.993 1.00 223.26 ? 805  GLN A N   1 
ATOM   5730 C CA  . GLN A 1 787  ? 166.902 114.345 159.601 1.00 215.80 ? 805  GLN A CA  1 
ATOM   5731 C C   . GLN A 1 787  ? 165.483 114.269 159.059 1.00 214.16 ? 805  GLN A C   1 
ATOM   5732 O O   . GLN A 1 787  ? 164.611 113.592 159.609 1.00 220.86 ? 805  GLN A O   1 
ATOM   5733 C CB  . GLN A 1 787  ? 167.839 113.492 158.736 1.00 218.00 ? 805  GLN A CB  1 
ATOM   5734 C CG  . GLN A 1 787  ? 167.545 111.992 158.778 1.00 234.09 ? 805  GLN A CG  1 
ATOM   5735 C CD  . GLN A 1 787  ? 168.514 111.178 157.942 1.00 236.13 ? 805  GLN A CD  1 
ATOM   5736 O OE1 . GLN A 1 787  ? 168.104 110.412 157.070 1.00 234.71 ? 805  GLN A OE1 1 
ATOM   5737 N NE2 . GLN A 1 787  ? 169.806 111.333 158.209 1.00 234.09 ? 805  GLN A NE2 1 
ATOM   5738 N N   . GLN A 1 788  ? 165.278 114.991 157.959 1.00 207.03 ? 806  GLN A N   1 
ATOM   5739 C CA  . GLN A 1 788  ? 164.066 114.938 157.157 1.00 204.27 ? 806  GLN A CA  1 
ATOM   5740 C C   . GLN A 1 788  ? 164.487 114.942 155.694 1.00 202.97 ? 806  GLN A C   1 
ATOM   5741 O O   . GLN A 1 788  ? 165.654 115.170 155.370 1.00 204.25 ? 806  GLN A O   1 
ATOM   5742 C CB  . GLN A 1 788  ? 163.134 116.119 157.463 1.00 199.07 ? 806  GLN A CB  1 
ATOM   5743 C CG  . GLN A 1 788  ? 162.136 115.871 158.589 1.00 201.02 ? 806  GLN A CG  1 
ATOM   5744 C CD  . GLN A 1 788  ? 160.953 116.824 158.546 1.00 198.39 ? 806  GLN A CD  1 
ATOM   5745 O OE1 . GLN A 1 788  ? 160.399 117.100 157.482 1.00 198.17 ? 806  GLN A OE1 1 
ATOM   5746 N NE2 . GLN A 1 788  ? 160.563 117.333 159.708 1.00 192.61 ? 806  GLN A NE2 1 
ATOM   5747 N N   . THR A 1 789  ? 163.531 114.675 154.806 1.00 200.96 ? 807  THR A N   1 
ATOM   5748 C CA  . THR A 1 789  ? 163.773 114.702 153.368 1.00 203.90 ? 807  THR A CA  1 
ATOM   5749 C C   . THR A 1 789  ? 162.604 115.393 152.688 1.00 201.38 ? 807  THR A C   1 
ATOM   5750 O O   . THR A 1 789  ? 161.454 115.211 153.098 1.00 196.78 ? 807  THR A O   1 
ATOM   5751 C CB  . THR A 1 789  ? 163.954 113.286 152.806 1.00 207.99 ? 807  THR A CB  1 
ATOM   5752 O OG1 . THR A 1 789  ? 164.931 112.583 153.583 1.00 211.80 ? 807  THR A OG1 1 
ATOM   5753 C CG2 . THR A 1 789  ? 164.411 113.336 151.352 1.00 206.01 ? 807  THR A CG2 1 
ATOM   5754 N N   . LEU A 1 790  ? 162.898 116.186 151.657 1.00 202.96 ? 808  LEU A N   1 
ATOM   5755 C CA  . LEU A 1 790  ? 161.867 116.910 150.927 1.00 202.43 ? 808  LEU A CA  1 
ATOM   5756 C C   . LEU A 1 790  ? 162.301 117.072 149.478 1.00 205.36 ? 808  LEU A C   1 
ATOM   5757 O O   . LEU A 1 790  ? 163.391 116.652 149.083 1.00 206.45 ? 808  LEU A O   1 
ATOM   5758 C CB  . LEU A 1 790  ? 161.572 118.272 151.580 1.00 200.05 ? 808  LEU A CB  1 
ATOM   5759 C CG  . LEU A 1 790  ? 162.418 119.500 151.221 1.00 197.00 ? 808  LEU A CG  1 
ATOM   5760 C CD1 . LEU A 1 790  ? 161.903 120.718 151.972 1.00 184.32 ? 808  LEU A CD1 1 
ATOM   5761 C CD2 . LEU A 1 790  ? 163.888 119.261 151.521 1.00 200.30 ? 808  LEU A CD2 1 
ATOM   5762 N N   . LEU A 1 791  ? 161.420 117.681 148.685 1.00 204.84 ? 809  LEU A N   1 
ATOM   5763 C CA  . LEU A 1 791  ? 161.644 117.927 147.264 1.00 203.44 ? 809  LEU A CA  1 
ATOM   5764 C C   . LEU A 1 791  ? 161.589 119.429 147.024 1.00 201.88 ? 809  LEU A C   1 
ATOM   5765 O O   . LEU A 1 791  ? 160.551 120.058 147.254 1.00 198.27 ? 809  LEU A O   1 
ATOM   5766 C CB  . LEU A 1 791  ? 160.594 117.205 146.416 1.00 199.45 ? 809  LEU A CB  1 
ATOM   5767 C CG  . LEU A 1 791  ? 160.724 117.285 144.891 1.00 196.17 ? 809  LEU A CG  1 
ATOM   5768 C CD1 . LEU A 1 791  ? 161.846 116.385 144.401 1.00 202.98 ? 809  LEU A CD1 1 
ATOM   5769 C CD2 . LEU A 1 791  ? 159.409 116.910 144.228 1.00 191.29 ? 809  LEU A CD2 1 
ATOM   5770 N N   . VAL A 1 792  ? 162.695 119.991 146.559 1.00 203.65 ? 810  VAL A N   1 
ATOM   5771 C CA  . VAL A 1 792  ? 162.806 121.419 146.267 1.00 201.34 ? 810  VAL A CA  1 
ATOM   5772 C C   . VAL A 1 792  ? 162.592 121.609 144.768 1.00 200.23 ? 810  VAL A C   1 
ATOM   5773 O O   . VAL A 1 792  ? 163.317 120.990 143.975 1.00 201.12 ? 810  VAL A O   1 
ATOM   5774 C CB  . VAL A 1 792  ? 164.177 121.974 146.693 1.00 200.07 ? 810  VAL A CB  1 
ATOM   5775 C CG1 . VAL A 1 792  ? 164.172 123.501 146.656 1.00 193.09 ? 810  VAL A CG1 1 
ATOM   5776 C CG2 . VAL A 1 792  ? 164.544 121.461 148.078 1.00 198.47 ? 810  VAL A CG2 1 
ATOM   5777 N N   . PRO A 1 793  ? 161.627 122.426 144.331 1.00 197.93 ? 811  PRO A N   1 
ATOM   5778 C CA  . PRO A 1 793  ? 161.508 122.688 142.893 1.00 198.49 ? 811  PRO A CA  1 
ATOM   5779 C C   . PRO A 1 793  ? 162.671 123.520 142.375 1.00 199.72 ? 811  PRO A C   1 
ATOM   5780 O O   . PRO A 1 793  ? 163.351 124.231 143.118 1.00 199.05 ? 811  PRO A O   1 
ATOM   5781 C CB  . PRO A 1 793  ? 160.184 123.452 142.761 1.00 194.62 ? 811  PRO A CB  1 
ATOM   5782 C CG  . PRO A 1 793  ? 159.489 123.283 144.050 1.00 194.94 ? 811  PRO A CG  1 
ATOM   5783 C CD  . PRO A 1 793  ? 160.547 123.104 145.074 1.00 193.03 ? 811  PRO A CD  1 
ATOM   5784 N N   . SER A 1 794  ? 162.891 123.415 141.068 1.00 201.31 ? 812  SER A N   1 
ATOM   5785 C CA  . SER A 1 794  ? 163.925 124.204 140.415 1.00 202.64 ? 812  SER A CA  1 
ATOM   5786 C C   . SER A 1 794  ? 163.601 125.690 140.503 1.00 200.52 ? 812  SER A C   1 
ATOM   5787 O O   . SER A 1 794  ? 162.456 126.104 140.298 1.00 196.92 ? 812  SER A O   1 
ATOM   5788 C CB  . SER A 1 794  ? 164.063 123.788 138.951 1.00 203.31 ? 812  SER A CB  1 
ATOM   5789 O OG  . SER A 1 794  ? 164.668 124.815 138.184 1.00 202.44 ? 812  SER A OG  1 
ATOM   5790 N N   . GLU A 1 795  ? 164.625 126.492 140.801 1.00 200.28 ? 813  GLU A N   1 
ATOM   5791 C CA  . GLU A 1 795  ? 164.489 127.947 140.901 1.00 197.42 ? 813  GLU A CA  1 
ATOM   5792 C C   . GLU A 1 795  ? 163.441 128.330 141.943 1.00 193.85 ? 813  GLU A C   1 
ATOM   5793 O O   . GLU A 1 795  ? 162.632 129.235 141.731 1.00 190.53 ? 813  GLU A O   1 
ATOM   5794 C CB  . GLU A 1 795  ? 164.152 128.571 139.543 1.00 197.62 ? 813  GLU A CB  1 
ATOM   5795 C CG  . GLU A 1 795  ? 165.136 128.243 138.410 1.00 199.39 ? 813  GLU A CG  1 
ATOM   5796 C CD  . GLU A 1 795  ? 166.369 129.132 138.407 1.00 200.12 ? 813  GLU A CD  1 
ATOM   5797 O OE1 . GLU A 1 795  ? 166.250 130.340 138.702 1.00 198.95 ? 813  GLU A OE1 1 
ATOM   5798 O OE2 . GLU A 1 795  ? 167.467 128.615 138.110 1.00 202.40 ? 813  GLU A OE2 1 
ATOM   5799 N N   . ASP A 1 796  ? 163.455 127.634 143.077 1.00 194.53 ? 814  ASP A N   1 
ATOM   5800 C CA  . ASP A 1 796  ? 162.445 127.829 144.105 1.00 193.94 ? 814  ASP A CA  1 
ATOM   5801 C C   . ASP A 1 796  ? 163.007 127.413 145.457 1.00 192.90 ? 814  ASP A C   1 
ATOM   5802 O O   . ASP A 1 796  ? 164.061 126.775 145.550 1.00 192.59 ? 814  ASP A O   1 
ATOM   5803 C CB  . ASP A 1 796  ? 161.171 127.040 143.785 1.00 195.38 ? 814  ASP A CB  1 
ATOM   5804 C CG  . ASP A 1 796  ? 159.920 127.703 144.328 1.00 197.24 ? 814  ASP A CG  1 
ATOM   5805 O OD1 . ASP A 1 796  ? 160.023 128.464 145.314 1.00 193.90 ? 814  ASP A OD1 1 
ATOM   5806 O OD2 . ASP A 1 796  ? 158.830 127.464 143.767 1.00 202.09 ? 814  ASP A OD2 1 
ATOM   5807 N N   . GLY A 1 797  ? 162.283 127.790 146.502 1.00 189.68 ? 815  GLY A N   1 
ATOM   5808 C CA  . GLY A 1 797  ? 162.640 127.445 147.871 1.00 184.51 ? 815  GLY A CA  1 
ATOM   5809 C C   . GLY A 1 797  ? 161.577 126.566 148.498 1.00 182.48 ? 815  GLY A C   1 
ATOM   5810 O O   . GLY A 1 797  ? 160.382 126.785 148.289 1.00 180.93 ? 815  GLY A O   1 
ATOM   5811 N N   . ALA A 1 798  ? 162.022 125.571 149.265 1.00 181.82 ? 816  ALA A N   1 
ATOM   5812 C CA  . ALA A 1 798  ? 161.145 124.646 149.972 1.00 177.58 ? 816  ALA A CA  1 
ATOM   5813 C C   . ALA A 1 798  ? 161.430 124.717 151.464 1.00 174.28 ? 816  ALA A C   1 
ATOM   5814 O O   . ALA A 1 798  ? 162.589 124.681 151.885 1.00 174.45 ? 816  ALA A O   1 
ATOM   5815 C CB  . ALA A 1 798  ? 161.334 123.212 149.474 1.00 182.15 ? 816  ALA A CB  1 
ATOM   5816 N N   . THR A 1 799  ? 160.366 124.798 152.258 1.00 171.83 ? 817  THR A N   1 
ATOM   5817 C CA  . THR A 1 799  ? 160.458 125.012 153.697 1.00 178.76 ? 817  THR A CA  1 
ATOM   5818 C C   . THR A 1 799  ? 160.209 123.697 154.423 1.00 177.60 ? 817  THR A C   1 
ATOM   5819 O O   . THR A 1 799  ? 159.332 122.921 154.029 1.00 176.92 ? 817  THR A O   1 
ATOM   5820 C CB  . THR A 1 799  ? 159.452 126.079 154.147 1.00 192.76 ? 817  THR A CB  1 
ATOM   5821 O OG1 . THR A 1 799  ? 159.938 127.374 153.775 1.00 195.95 ? 817  THR A OG1 1 
ATOM   5822 C CG2 . THR A 1 799  ? 159.230 126.052 155.666 1.00 191.08 ? 817  THR A CG2 1 
ATOM   5823 N N   . VAL A 1 800  ? 160.991 123.451 155.473 1.00 176.33 ? 818  VAL A N   1 
ATOM   5824 C CA  . VAL A 1 800  ? 160.805 122.316 156.369 1.00 174.09 ? 818  VAL A CA  1 
ATOM   5825 C C   . VAL A 1 800  ? 160.820 122.834 157.800 1.00 174.99 ? 818  VAL A C   1 
ATOM   5826 O O   . VAL A 1 800  ? 161.535 123.793 158.115 1.00 175.38 ? 818  VAL A O   1 
ATOM   5827 C CB  . VAL A 1 800  ? 161.881 121.227 156.160 1.00 174.75 ? 818  VAL A CB  1 
ATOM   5828 C CG1 . VAL A 1 800  ? 163.286 121.757 156.452 1.00 178.89 ? 818  VAL A CG1 1 
ATOM   5829 C CG2 . VAL A 1 800  ? 161.579 119.999 157.014 1.00 174.43 ? 818  VAL A CG2 1 
ATOM   5830 N N   . LEU A 1 801  ? 160.032 122.193 158.661 1.00 175.16 ? 819  LEU A N   1 
ATOM   5831 C CA  . LEU A 1 801  ? 159.831 122.611 160.040 1.00 175.98 ? 819  LEU A CA  1 
ATOM   5832 C C   . LEU A 1 801  ? 160.427 121.592 161.002 1.00 174.36 ? 819  LEU A C   1 
ATOM   5833 O O   . LEU A 1 801  ? 160.544 120.405 160.683 1.00 175.97 ? 819  LEU A O   1 
ATOM   5834 C CB  . LEU A 1 801  ? 158.338 122.791 160.339 1.00 179.00 ? 819  LEU A CB  1 
ATOM   5835 C CG  . LEU A 1 801  ? 157.764 124.210 160.265 1.00 184.29 ? 819  LEU A CG  1 
ATOM   5836 C CD1 . LEU A 1 801  ? 158.338 125.100 161.359 1.00 182.48 ? 819  LEU A CD1 1 
ATOM   5837 C CD2 . LEU A 1 801  ? 158.009 124.821 158.890 1.00 180.25 ? 819  LEU A CD2 1 
ATOM   5838 N N   . PHE A 1 802  ? 160.810 122.077 162.185 1.00 171.94 ? 820  PHE A N   1 
ATOM   5839 C CA  . PHE A 1 802  ? 161.392 121.243 163.230 1.00 172.94 ? 820  PHE A CA  1 
ATOM   5840 C C   . PHE A 1 802  ? 161.015 121.794 164.607 1.00 176.45 ? 820  PHE A C   1 
ATOM   5841 O O   . PHE A 1 802  ? 161.325 122.958 164.894 1.00 173.57 ? 820  PHE A O   1 
ATOM   5842 C CB  . PHE A 1 802  ? 162.912 121.191 163.080 1.00 173.88 ? 820  PHE A CB  1 
ATOM   5843 C CG  . PHE A 1 802  ? 163.388 120.194 162.063 1.00 178.70 ? 820  PHE A CG  1 
ATOM   5844 C CD1 . PHE A 1 802  ? 163.591 118.871 162.414 1.00 184.38 ? 820  PHE A CD1 1 
ATOM   5845 C CD2 . PHE A 1 802  ? 163.633 120.579 160.757 1.00 179.87 ? 820  PHE A CD2 1 
ATOM   5846 C CE1 . PHE A 1 802  ? 164.029 117.951 161.482 1.00 193.23 ? 820  PHE A CE1 1 
ATOM   5847 C CE2 . PHE A 1 802  ? 164.070 119.663 159.820 1.00 183.09 ? 820  PHE A CE2 1 
ATOM   5848 C CZ  . PHE A 1 802  ? 164.268 118.348 160.184 1.00 191.46 ? 820  PHE A CZ  1 
ATOM   5849 N N   . PRO A 1 803  ? 160.334 121.024 165.496 1.00 181.00 ? 821  PRO A N   1 
ATOM   5850 C CA  . PRO A 1 803  ? 160.095 121.522 166.859 1.00 182.26 ? 821  PRO A CA  1 
ATOM   5851 C C   . PRO A 1 803  ? 161.307 121.290 167.747 1.00 182.00 ? 821  PRO A C   1 
ATOM   5852 O O   . PRO A 1 803  ? 161.621 120.152 168.109 1.00 183.35 ? 821  PRO A O   1 
ATOM   5853 C CB  . PRO A 1 803  ? 158.883 120.701 167.319 1.00 184.94 ? 821  PRO A CB  1 
ATOM   5854 C CG  . PRO A 1 803  ? 159.003 119.428 166.594 1.00 187.22 ? 821  PRO A CG  1 
ATOM   5855 C CD  . PRO A 1 803  ? 159.647 119.735 165.273 1.00 179.90 ? 821  PRO A CD  1 
ATOM   5856 N N   . ILE A 1 804  ? 161.983 122.377 168.117 1.00 178.05 ? 822  ILE A N   1 
ATOM   5857 C CA  . ILE A 1 804  ? 163.212 122.332 168.901 1.00 173.92 ? 822  ILE A CA  1 
ATOM   5858 C C   . ILE A 1 804  ? 162.916 122.890 170.284 1.00 175.86 ? 822  ILE A C   1 
ATOM   5859 O O   . ILE A 1 804  ? 162.319 123.967 170.412 1.00 178.85 ? 822  ILE A O   1 
ATOM   5860 C CB  . ILE A 1 804  ? 164.341 123.127 168.217 1.00 168.60 ? 822  ILE A CB  1 
ATOM   5861 C CG1 . ILE A 1 804  ? 164.785 122.452 166.908 1.00 172.27 ? 822  ILE A CG1 1 
ATOM   5862 C CG2 . ILE A 1 804  ? 165.527 123.322 169.167 1.00 170.23 ? 822  ILE A CG2 1 
ATOM   5863 C CD1 . ILE A 1 804  ? 165.390 121.048 167.040 1.00 181.54 ? 822  ILE A CD1 1 
ATOM   5864 N N   . ARG A 1 805  ? 163.314 122.143 171.314 1.00 173.17 ? 823  ARG A N   1 
ATOM   5865 C CA  . ARG A 1 805  ? 163.248 122.595 172.699 1.00 171.41 ? 823  ARG A CA  1 
ATOM   5866 C C   . ARG A 1 805  ? 164.663 122.850 173.204 1.00 168.20 ? 823  ARG A C   1 
ATOM   5867 O O   . ARG A 1 805  ? 165.431 121.887 173.361 1.00 171.84 ? 823  ARG A O   1 
ATOM   5868 C CB  . ARG A 1 805  ? 162.553 121.556 173.578 1.00 174.77 ? 823  ARG A CB  1 
ATOM   5869 C CG  . ARG A 1 805  ? 162.510 121.947 175.047 1.00 173.52 ? 823  ARG A CG  1 
ATOM   5870 C CD  . ARG A 1 805  ? 161.343 121.302 175.769 1.00 175.86 ? 823  ARG A CD  1 
ATOM   5871 N NE  . ARG A 1 805  ? 161.268 119.867 175.521 1.00 179.93 ? 823  ARG A NE  1 
ATOM   5872 C CZ  . ARG A 1 805  ? 160.192 119.113 175.710 1.00 182.90 ? 823  ARG A CZ  1 
ATOM   5873 N NH1 . ARG A 1 805  ? 159.055 119.617 176.167 1.00 184.96 ? 823  ARG A NH1 1 
ATOM   5874 N NH2 . ARG A 1 805  ? 160.257 117.813 175.436 1.00 183.92 ? 823  ARG A NH2 1 
ATOM   5875 N N   . PRO A 1 806  ? 165.081 124.093 173.445 1.00 160.83 ? 824  PRO A N   1 
ATOM   5876 C CA  . PRO A 1 806  ? 166.387 124.299 174.078 1.00 160.27 ? 824  PRO A CA  1 
ATOM   5877 C C   . PRO A 1 806  ? 166.387 123.842 175.526 1.00 163.65 ? 824  PRO A C   1 
ATOM   5878 O O   . PRO A 1 806  ? 165.342 123.746 176.174 1.00 163.94 ? 824  PRO A O   1 
ATOM   5879 C CB  . PRO A 1 806  ? 166.603 125.812 173.975 1.00 151.82 ? 824  PRO A CB  1 
ATOM   5880 C CG  . PRO A 1 806  ? 165.691 126.266 172.906 1.00 152.07 ? 824  PRO A CG  1 
ATOM   5881 C CD  . PRO A 1 806  ? 164.505 125.372 172.993 1.00 159.96 ? 824  PRO A CD  1 
ATOM   5882 N N   . THR A 1 807  ? 167.591 123.549 176.027 1.00 166.63 ? 825  THR A N   1 
ATOM   5883 C CA  . THR A 1 807  ? 167.787 123.110 177.403 1.00 167.48 ? 825  THR A CA  1 
ATOM   5884 C C   . THR A 1 807  ? 169.013 123.749 178.054 1.00 165.78 ? 825  THR A C   1 
ATOM   5885 O O   . THR A 1 807  ? 169.421 123.309 179.136 1.00 161.67 ? 825  THR A O   1 
ATOM   5886 C CB  . THR A 1 807  ? 167.903 121.580 177.452 1.00 172.45 ? 825  THR A CB  1 
ATOM   5887 O OG1 . THR A 1 807  ? 168.674 121.123 176.335 1.00 174.91 ? 825  THR A OG1 1 
ATOM   5888 C CG2 . THR A 1 807  ? 166.523 120.943 177.397 1.00 173.54 ? 825  THR A CG2 1 
ATOM   5889 N N   . HIS A 1 808  ? 169.600 124.778 177.439 1.00 167.28 ? 826  HIS A N   1 
ATOM   5890 C CA  . HIS A 1 808  ? 170.801 125.421 177.953 1.00 165.94 ? 826  HIS A CA  1 
ATOM   5891 C C   . HIS A 1 808  ? 170.696 126.926 177.762 1.00 162.04 ? 826  HIS A C   1 
ATOM   5892 O O   . HIS A 1 808  ? 170.059 127.408 176.824 1.00 161.16 ? 826  HIS A O   1 
ATOM   5893 C CB  . HIS A 1 808  ? 172.061 124.899 177.251 1.00 166.25 ? 826  HIS A CB  1 
ATOM   5894 C CG  . HIS A 1 808  ? 172.638 123.671 177.881 1.00 172.56 ? 826  HIS A CG  1 
ATOM   5895 N ND1 . HIS A 1 808  ? 171.918 122.507 178.039 1.00 173.44 ? 826  HIS A ND1 1 
ATOM   5896 C CD2 . HIS A 1 808  ? 173.869 123.425 178.389 1.00 175.56 ? 826  HIS A CD2 1 
ATOM   5897 C CE1 . HIS A 1 808  ? 172.680 121.596 178.619 1.00 177.13 ? 826  HIS A CE1 1 
ATOM   5898 N NE2 . HIS A 1 808  ? 173.868 122.128 178.842 1.00 181.37 ? 826  HIS A NE2 1 
ATOM   5899 N N   . LEU A 1 809  ? 171.331 127.661 178.669 1.00 157.72 ? 827  LEU A N   1 
ATOM   5900 C CA  . LEU A 1 809  ? 171.393 129.109 178.568 1.00 156.71 ? 827  LEU A CA  1 
ATOM   5901 C C   . LEU A 1 809  ? 172.487 129.520 177.587 1.00 156.15 ? 827  LEU A C   1 
ATOM   5902 O O   . LEU A 1 809  ? 173.373 128.735 177.240 1.00 155.78 ? 827  LEU A O   1 
ATOM   5903 C CB  . LEU A 1 809  ? 171.663 129.740 179.938 1.00 154.25 ? 827  LEU A CB  1 
ATOM   5904 C CG  . LEU A 1 809  ? 170.475 130.351 180.689 1.00 153.01 ? 827  LEU A CG  1 
ATOM   5905 C CD1 . LEU A 1 809  ? 169.996 131.631 180.021 1.00 155.87 ? 827  LEU A CD1 1 
ATOM   5906 C CD2 . LEU A 1 809  ? 169.336 129.349 180.812 1.00 153.91 ? 827  LEU A CD2 1 
ATOM   5907 N N   . GLY A 1 810  ? 172.413 130.769 177.135 1.00 153.59 ? 828  GLY A N   1 
ATOM   5908 C CA  . GLY A 1 810  ? 173.490 131.341 176.348 1.00 153.10 ? 828  GLY A CA  1 
ATOM   5909 C C   . GLY A 1 810  ? 173.412 131.051 174.863 1.00 156.67 ? 828  GLY A C   1 
ATOM   5910 O O   . GLY A 1 810  ? 172.327 130.820 174.325 1.00 156.25 ? 828  GLY A O   1 
ATOM   5911 N N   . GLU A 1 811  ? 174.560 131.067 174.190 1.00 159.95 ? 829  GLU A N   1 
ATOM   5912 C CA  . GLU A 1 811  ? 174.621 130.949 172.733 1.00 157.70 ? 829  GLU A CA  1 
ATOM   5913 C C   . GLU A 1 811  ? 174.763 129.477 172.364 1.00 155.20 ? 829  GLU A C   1 
ATOM   5914 O O   . GLU A 1 811  ? 175.850 128.903 172.461 1.00 160.30 ? 829  GLU A O   1 
ATOM   5915 C CB  . GLU A 1 811  ? 175.775 131.776 172.178 1.00 158.76 ? 829  GLU A CB  1 
ATOM   5916 C CG  . GLU A 1 811  ? 175.764 133.234 172.616 1.00 164.19 ? 829  GLU A CG  1 
ATOM   5917 C CD  . GLU A 1 811  ? 175.884 134.192 171.451 1.00 167.52 ? 829  GLU A CD  1 
ATOM   5918 O OE1 . GLU A 1 811  ? 175.012 134.155 170.558 1.00 165.31 ? 829  GLU A OE1 1 
ATOM   5919 O OE2 . GLU A 1 811  ? 176.847 134.986 171.430 1.00 168.69 ? 829  GLU A OE2 1 
ATOM   5920 N N   . ILE A 1 812  ? 173.663 128.868 171.933 1.00 150.98 ? 830  ILE A N   1 
ATOM   5921 C CA  . ILE A 1 812  ? 173.647 127.472 171.502 1.00 150.03 ? 830  ILE A CA  1 
ATOM   5922 C C   . ILE A 1 812  ? 174.031 127.420 170.026 1.00 146.97 ? 830  ILE A C   1 
ATOM   5923 O O   . ILE A 1 812  ? 173.573 128.278 169.255 1.00 144.85 ? 830  ILE A O   1 
ATOM   5924 C CB  . ILE A 1 812  ? 172.270 126.831 171.742 1.00 148.54 ? 830  ILE A CB  1 
ATOM   5925 C CG1 . ILE A 1 812  ? 172.060 126.654 173.249 1.00 154.87 ? 830  ILE A CG1 1 
ATOM   5926 C CG2 . ILE A 1 812  ? 172.134 125.499 170.950 1.00 152.31 ? 830  ILE A CG2 1 
ATOM   5927 C CD1 . ILE A 1 812  ? 170.702 126.130 173.644 1.00 161.55 ? 830  ILE A CD1 1 
ATOM   5928 N N   . PRO A 1 813  ? 174.857 126.464 169.579 1.00 147.93 ? 831  PRO A N   1 
ATOM   5929 C CA  . PRO A 1 813  ? 175.027 126.273 168.136 1.00 146.08 ? 831  PRO A CA  1 
ATOM   5930 C C   . PRO A 1 813  ? 173.927 125.403 167.554 1.00 151.05 ? 831  PRO A C   1 
ATOM   5931 O O   . PRO A 1 813  ? 173.463 124.447 168.179 1.00 161.99 ? 831  PRO A O   1 
ATOM   5932 C CB  . PRO A 1 813  ? 176.393 125.586 168.031 1.00 141.91 ? 831  PRO A CB  1 
ATOM   5933 C CG  . PRO A 1 813  ? 176.514 124.816 169.273 1.00 140.95 ? 831  PRO A CG  1 
ATOM   5934 C CD  . PRO A 1 813  ? 175.765 125.573 170.335 1.00 149.46 ? 831  PRO A CD  1 
ATOM   5935 N N   . ILE A 1 814  ? 173.507 125.758 166.344 1.00 144.42 ? 832  ILE A N   1 
ATOM   5936 C CA  . ILE A 1 814  ? 172.562 124.981 165.553 1.00 145.80 ? 832  ILE A CA  1 
ATOM   5937 C C   . ILE A 1 814  ? 173.182 124.802 164.177 1.00 151.07 ? 832  ILE A C   1 
ATOM   5938 O O   . ILE A 1 814  ? 173.545 125.786 163.525 1.00 154.04 ? 832  ILE A O   1 
ATOM   5939 C CB  . ILE A 1 814  ? 171.174 125.662 165.478 1.00 149.98 ? 832  ILE A CB  1 
ATOM   5940 C CG1 . ILE A 1 814  ? 170.197 124.906 164.561 1.00 159.59 ? 832  ILE A CG1 1 
ATOM   5941 C CG2 . ILE A 1 814  ? 171.270 127.118 165.002 1.00 151.11 ? 832  ILE A CG2 1 
ATOM   5942 C CD1 . ILE A 1 814  ? 169.916 123.481 164.972 1.00 165.22 ? 832  ILE A CD1 1 
ATOM   5943 N N   . THR A 1 815  ? 173.322 123.548 163.751 1.00 155.64 ? 833  THR A N   1 
ATOM   5944 C CA  . THR A 1 815  ? 173.957 123.193 162.490 1.00 161.90 ? 833  THR A CA  1 
ATOM   5945 C C   . THR A 1 815  ? 172.954 122.447 161.627 1.00 164.84 ? 833  THR A C   1 
ATOM   5946 O O   . THR A 1 815  ? 172.301 121.509 162.097 1.00 172.00 ? 833  THR A O   1 
ATOM   5947 C CB  . THR A 1 815  ? 175.200 122.329 162.721 1.00 167.92 ? 833  THR A CB  1 
ATOM   5948 O OG1 . THR A 1 815  ? 176.028 122.935 163.720 1.00 169.47 ? 833  THR A OG1 1 
ATOM   5949 C CG2 . THR A 1 815  ? 175.994 122.176 161.430 1.00 169.50 ? 833  THR A CG2 1 
ATOM   5950 N N   . VAL A 1 816  ? 172.835 122.869 160.371 1.00 161.69 ? 834  VAL A N   1 
ATOM   5951 C CA  . VAL A 1 816  ? 171.906 122.286 159.412 1.00 164.03 ? 834  VAL A CA  1 
ATOM   5952 C C   . VAL A 1 816  ? 172.684 121.961 158.148 1.00 165.69 ? 834  VAL A C   1 
ATOM   5953 O O   . VAL A 1 816  ? 173.359 122.836 157.591 1.00 165.19 ? 834  VAL A O   1 
ATOM   5954 C CB  . VAL A 1 816  ? 170.740 123.241 159.101 1.00 165.83 ? 834  VAL A CB  1 
ATOM   5955 C CG1 . VAL A 1 816  ? 169.811 122.617 158.067 1.00 173.00 ? 834  VAL A CG1 1 
ATOM   5956 C CG2 . VAL A 1 816  ? 169.997 123.610 160.384 1.00 165.66 ? 834  VAL A CG2 1 
ATOM   5957 N N   . THR A 1 817  ? 172.579 120.712 157.693 1.00 170.38 ? 835  THR A N   1 
ATOM   5958 C CA  . THR A 1 817  ? 173.299 120.227 156.520 1.00 177.68 ? 835  THR A CA  1 
ATOM   5959 C C   . THR A 1 817  ? 172.296 119.735 155.488 1.00 180.37 ? 835  THR A C   1 
ATOM   5960 O O   . THR A 1 817  ? 171.531 118.805 155.759 1.00 182.86 ? 835  THR A O   1 
ATOM   5961 C CB  . THR A 1 817  ? 174.267 119.105 156.901 1.00 185.18 ? 835  THR A CB  1 
ATOM   5962 O OG1 . THR A 1 817  ? 175.068 119.519 158.015 1.00 182.63 ? 835  THR A OG1 1 
ATOM   5963 C CG2 . THR A 1 817  ? 175.173 118.747 155.729 1.00 185.86 ? 835  THR A CG2 1 
ATOM   5964 N N   . ALA A 1 818  ? 172.313 120.345 154.307 1.00 179.81 ? 836  ALA A N   1 
ATOM   5965 C CA  . ALA A 1 818  ? 171.478 119.932 153.188 1.00 185.96 ? 836  ALA A CA  1 
ATOM   5966 C C   . ALA A 1 818  ? 172.324 119.122 152.217 1.00 187.39 ? 836  ALA A C   1 
ATOM   5967 O O   . ALA A 1 818  ? 173.364 119.599 151.750 1.00 185.07 ? 836  ALA A O   1 
ATOM   5968 C CB  . ALA A 1 818  ? 170.871 121.144 152.481 1.00 187.28 ? 836  ALA A CB  1 
ATOM   5969 N N   . LEU A 1 819  ? 171.879 117.901 151.923 1.00 191.29 ? 837  LEU A N   1 
ATOM   5970 C CA  . LEU A 1 819  ? 172.575 116.987 151.027 1.00 193.29 ? 837  LEU A CA  1 
ATOM   5971 C C   . LEU A 1 819  ? 171.670 116.651 149.853 1.00 196.91 ? 837  LEU A C   1 
ATOM   5972 O O   . LEU A 1 819  ? 170.504 116.290 150.046 1.00 198.80 ? 837  LEU A O   1 
ATOM   5973 C CB  . LEU A 1 819  ? 172.984 115.703 151.754 1.00 194.26 ? 837  LEU A CB  1 
ATOM   5974 C CG  . LEU A 1 819  ? 173.835 115.861 153.017 1.00 191.46 ? 837  LEU A CG  1 
ATOM   5975 C CD1 . LEU A 1 819  ? 174.126 114.497 153.624 1.00 188.66 ? 837  LEU A CD1 1 
ATOM   5976 C CD2 . LEU A 1 819  ? 175.129 116.605 152.724 1.00 187.43 ? 837  LEU A CD2 1 
ATOM   5977 N N   . SER A 1 820  ? 172.207 116.777 148.647 1.00 197.82 ? 838  SER A N   1 
ATOM   5978 C CA  . SER A 1 820  ? 171.539 116.375 147.421 1.00 201.87 ? 838  SER A CA  1 
ATOM   5979 C C   . SER A 1 820  ? 172.570 115.711 146.522 1.00 202.74 ? 838  SER A C   1 
ATOM   5980 O O   . SER A 1 820  ? 173.775 115.925 146.695 1.00 198.62 ? 838  SER A O   1 
ATOM   5981 C CB  . SER A 1 820  ? 170.904 117.571 146.699 1.00 200.54 ? 838  SER A CB  1 
ATOM   5982 O OG  . SER A 1 820  ? 171.885 118.335 146.021 1.00 202.77 ? 838  SER A OG  1 
ATOM   5983 N N   . PRO A 1 821  ? 172.134 114.882 145.564 1.00 204.67 ? 839  PRO A N   1 
ATOM   5984 C CA  . PRO A 1 821  ? 173.110 114.318 144.615 1.00 204.77 ? 839  PRO A CA  1 
ATOM   5985 C C   . PRO A 1 821  ? 173.842 115.375 143.810 1.00 205.36 ? 839  PRO A C   1 
ATOM   5986 O O   . PRO A 1 821  ? 175.022 115.190 143.484 1.00 204.34 ? 839  PRO A O   1 
ATOM   5987 C CB  . PRO A 1 821  ? 172.249 113.424 143.712 1.00 202.06 ? 839  PRO A CB  1 
ATOM   5988 C CG  . PRO A 1 821  ? 171.051 113.108 144.512 1.00 199.44 ? 839  PRO A CG  1 
ATOM   5989 C CD  . PRO A 1 821  ? 170.788 114.321 145.344 1.00 201.38 ? 839  PRO A CD  1 
ATOM   5990 N N   . THR A 1 822  ? 173.177 116.482 143.480 1.00 205.97 ? 840  THR A N   1 
ATOM   5991 C CA  . THR A 1 822  ? 173.801 117.515 142.660 1.00 206.22 ? 840  THR A CA  1 
ATOM   5992 C C   . THR A 1 822  ? 174.817 118.326 143.456 1.00 205.02 ? 840  THR A C   1 
ATOM   5993 O O   . THR A 1 822  ? 175.922 118.595 142.973 1.00 205.03 ? 840  THR A O   1 
ATOM   5994 C CB  . THR A 1 822  ? 172.728 118.434 142.077 1.00 206.41 ? 840  THR A CB  1 
ATOM   5995 O OG1 . THR A 1 822  ? 171.784 118.780 143.099 1.00 210.14 ? 840  THR A OG1 1 
ATOM   5996 C CG2 . THR A 1 822  ? 172.000 117.745 140.933 1.00 201.41 ? 840  THR A CG2 1 
ATOM   5997 N N   . ALA A 1 823  ? 174.462 118.725 144.676 1.00 203.47 ? 841  ALA A N   1 
ATOM   5998 C CA  . ALA A 1 823  ? 175.322 119.571 145.490 1.00 196.85 ? 841  ALA A CA  1 
ATOM   5999 C C   . ALA A 1 823  ? 174.935 119.401 146.954 1.00 196.40 ? 841  ALA A C   1 
ATOM   6000 O O   . ALA A 1 823  ? 174.008 118.660 147.292 1.00 197.70 ? 841  ALA A O   1 
ATOM   6001 C CB  . ALA A 1 823  ? 175.224 121.036 145.052 1.00 190.30 ? 841  ALA A CB  1 
ATOM   6002 N N   . SER A 1 824  ? 175.661 120.099 147.825 1.00 195.38 ? 842  SER A N   1 
ATOM   6003 C CA  . SER A 1 824  ? 175.419 120.033 149.258 1.00 193.02 ? 842  SER A CA  1 
ATOM   6004 C C   . SER A 1 824  ? 175.881 121.332 149.900 1.00 189.52 ? 842  SER A C   1 
ATOM   6005 O O   . SER A 1 824  ? 176.660 122.093 149.321 1.00 189.28 ? 842  SER A O   1 
ATOM   6006 C CB  . SER A 1 824  ? 176.140 118.839 149.895 1.00 194.25 ? 842  SER A CB  1 
ATOM   6007 O OG  . SER A 1 824  ? 177.542 118.943 149.723 1.00 191.12 ? 842  SER A OG  1 
ATOM   6008 N N   . ASP A 1 825  ? 175.385 121.577 151.110 1.00 185.21 ? 843  ASP A N   1 
ATOM   6009 C CA  . ASP A 1 825  ? 175.760 122.763 151.867 1.00 177.46 ? 843  ASP A CA  1 
ATOM   6010 C C   . ASP A 1 825  ? 175.562 122.483 153.349 1.00 174.02 ? 843  ASP A C   1 
ATOM   6011 O O   . ASP A 1 825  ? 174.864 121.543 153.733 1.00 176.09 ? 843  ASP A O   1 
ATOM   6012 C CB  . ASP A 1 825  ? 174.942 123.986 151.438 1.00 173.53 ? 843  ASP A CB  1 
ATOM   6013 C CG  . ASP A 1 825  ? 175.626 125.297 151.779 1.00 169.87 ? 843  ASP A CG  1 
ATOM   6014 O OD1 . ASP A 1 825  ? 176.836 125.435 151.502 1.00 168.96 ? 843  ASP A OD1 1 
ATOM   6015 O OD2 . ASP A 1 825  ? 174.951 126.191 152.331 1.00 168.17 ? 843  ASP A OD2 1 
ATOM   6016 N N   . ALA A 1 826  ? 176.193 123.313 154.177 1.00 168.48 ? 844  ALA A N   1 
ATOM   6017 C CA  . ALA A 1 826  ? 176.070 123.202 155.624 1.00 166.67 ? 844  ALA A CA  1 
ATOM   6018 C C   . ALA A 1 826  ? 176.228 124.585 156.232 1.00 160.55 ? 844  ALA A C   1 
ATOM   6019 O O   . ALA A 1 826  ? 177.126 125.334 155.836 1.00 160.82 ? 844  ALA A O   1 
ATOM   6020 C CB  . ALA A 1 826  ? 177.119 122.244 156.199 1.00 168.84 ? 844  ALA A CB  1 
ATOM   6021 N N   . VAL A 1 827  ? 175.356 124.918 157.184 1.00 155.97 ? 845  VAL A N   1 
ATOM   6022 C CA  . VAL A 1 827  ? 175.350 126.226 157.831 1.00 150.63 ? 845  VAL A CA  1 
ATOM   6023 C C   . VAL A 1 827  ? 175.232 126.025 159.335 1.00 151.26 ? 845  VAL A C   1 
ATOM   6024 O O   . VAL A 1 827  ? 174.362 125.280 159.801 1.00 152.80 ? 845  VAL A O   1 
ATOM   6025 C CB  . VAL A 1 827  ? 174.203 127.114 157.311 1.00 150.57 ? 845  VAL A CB  1 
ATOM   6026 C CG1 . VAL A 1 827  ? 174.103 128.397 158.130 1.00 150.15 ? 845  VAL A CG1 1 
ATOM   6027 C CG2 . VAL A 1 827  ? 174.401 127.429 155.831 1.00 155.70 ? 845  VAL A CG2 1 
ATOM   6028 N N   . THR A 1 828  ? 176.104 126.696 160.085 1.00 153.65 ? 846  THR A N   1 
ATOM   6029 C CA  . THR A 1 828  ? 176.096 126.698 161.543 1.00 157.56 ? 846  THR A CA  1 
ATOM   6030 C C   . THR A 1 828  ? 175.849 128.120 162.027 1.00 151.95 ? 846  THR A C   1 
ATOM   6031 O O   . THR A 1 828  ? 176.470 129.064 161.526 1.00 148.70 ? 846  THR A O   1 
ATOM   6032 C CB  . THR A 1 828  ? 177.422 126.175 162.103 1.00 163.68 ? 846  THR A CB  1 
ATOM   6033 O OG1 . THR A 1 828  ? 177.761 124.939 161.463 1.00 170.20 ? 846  THR A OG1 1 
ATOM   6034 C CG2 . THR A 1 828  ? 177.327 125.950 163.607 1.00 161.66 ? 846  THR A CG2 1 
ATOM   6035 N N   . GLN A 1 829  ? 174.937 128.272 162.989 1.00 151.24 ? 847  GLN A N   1 
ATOM   6036 C CA  . GLN A 1 829  ? 174.546 129.574 163.513 1.00 147.78 ? 847  GLN A CA  1 
ATOM   6037 C C   . GLN A 1 829  ? 174.420 129.518 165.030 1.00 147.26 ? 847  GLN A C   1 
ATOM   6038 O O   . GLN A 1 829  ? 174.337 128.446 165.635 1.00 148.73 ? 847  GLN A O   1 
ATOM   6039 C CB  . GLN A 1 829  ? 173.226 130.045 162.894 1.00 148.54 ? 847  GLN A CB  1 
ATOM   6040 C CG  . GLN A 1 829  ? 173.345 130.415 161.430 1.00 157.99 ? 847  GLN A CG  1 
ATOM   6041 C CD  . GLN A 1 829  ? 172.209 131.296 160.947 1.00 161.22 ? 847  GLN A CD  1 
ATOM   6042 O OE1 . GLN A 1 829  ? 171.313 131.660 161.708 1.00 160.52 ? 847  GLN A OE1 1 
ATOM   6043 N NE2 . GLN A 1 829  ? 172.251 131.655 159.673 1.00 160.52 ? 847  GLN A NE2 1 
ATOM   6044 N N   . MET A 1 830  ? 174.390 130.705 165.635 1.00 149.06 ? 848  MET A N   1 
ATOM   6045 C CA  . MET A 1 830  ? 174.247 130.882 167.073 1.00 158.90 ? 848  MET A CA  1 
ATOM   6046 C C   . MET A 1 830  ? 172.803 131.271 167.376 1.00 158.28 ? 848  MET A C   1 
ATOM   6047 O O   . MET A 1 830  ? 172.163 131.967 166.581 1.00 158.54 ? 848  MET A O   1 
ATOM   6048 C CB  . MET A 1 830  ? 175.186 131.987 167.579 1.00 164.30 ? 848  MET A CB  1 
ATOM   6049 C CG  . MET A 1 830  ? 176.662 131.934 167.123 1.00 165.80 ? 848  MET A CG  1 
ATOM   6050 S SD  . MET A 1 830  ? 177.653 130.423 167.025 1.00 180.14 ? 848  MET A SD  1 
ATOM   6051 C CE  . MET A 1 830  ? 177.075 129.386 168.361 1.00 152.72 ? 848  MET A CE  1 
ATOM   6052 N N   . ILE A 1 831  ? 172.290 130.807 168.517 1.00 152.66 ? 849  ILE A N   1 
ATOM   6053 C CA  . ILE A 1 831  ? 170.970 131.193 169.018 1.00 141.07 ? 849  ILE A CA  1 
ATOM   6054 C C   . ILE A 1 831  ? 171.110 131.546 170.491 1.00 149.30 ? 849  ILE A C   1 
ATOM   6055 O O   . ILE A 1 831  ? 171.585 130.727 171.284 1.00 154.34 ? 849  ILE A O   1 
ATOM   6056 C CB  . ILE A 1 831  ? 169.926 130.077 168.815 1.00 133.95 ? 849  ILE A CB  1 
ATOM   6057 C CG1 . ILE A 1 831  ? 169.426 130.064 167.366 1.00 143.67 ? 849  ILE A CG1 1 
ATOM   6058 C CG2 . ILE A 1 831  ? 168.731 130.206 169.777 1.00 141.84 ? 849  ILE A CG2 1 
ATOM   6059 C CD1 . ILE A 1 831  ? 168.586 131.276 166.950 1.00 152.35 ? 849  ILE A CD1 1 
ATOM   6060 N N   . LEU A 1 832  ? 170.679 132.750 170.857 1.00 148.04 ? 850  LEU A N   1 
ATOM   6061 C CA  . LEU A 1 832  ? 170.763 133.233 172.231 1.00 149.52 ? 850  LEU A CA  1 
ATOM   6062 C C   . LEU A 1 832  ? 169.520 132.780 172.989 1.00 145.91 ? 850  LEU A C   1 
ATOM   6063 O O   . LEU A 1 832  ? 168.459 133.403 172.881 1.00 146.61 ? 850  LEU A O   1 
ATOM   6064 C CB  . LEU A 1 832  ? 170.898 134.754 172.255 1.00 151.87 ? 850  LEU A CB  1 
ATOM   6065 C CG  . LEU A 1 832  ? 170.953 135.452 173.622 1.00 155.70 ? 850  LEU A CG  1 
ATOM   6066 C CD1 . LEU A 1 832  ? 172.216 135.079 174.378 1.00 156.32 ? 850  LEU A CD1 1 
ATOM   6067 C CD2 . LEU A 1 832  ? 170.870 136.961 173.460 1.00 153.03 ? 850  LEU A CD2 1 
ATOM   6068 N N   . VAL A 1 833  ? 169.655 131.713 173.769 1.00 144.44 ? 851  VAL A N   1 
ATOM   6069 C CA  . VAL A 1 833  ? 168.572 131.184 174.588 1.00 146.38 ? 851  VAL A CA  1 
ATOM   6070 C C   . VAL A 1 833  ? 168.661 131.837 175.959 1.00 149.56 ? 851  VAL A C   1 
ATOM   6071 O O   . VAL A 1 833  ? 169.678 131.706 176.653 1.00 151.17 ? 851  VAL A O   1 
ATOM   6072 C CB  . VAL A 1 833  ? 168.652 129.654 174.698 1.00 146.45 ? 851  VAL A CB  1 
ATOM   6073 C CG1 . VAL A 1 833  ? 167.543 129.121 175.610 1.00 151.48 ? 851  VAL A CG1 1 
ATOM   6074 C CG2 . VAL A 1 833  ? 168.589 129.038 173.311 1.00 146.21 ? 851  VAL A CG2 1 
ATOM   6075 N N   . LYS A 1 834  ? 167.598 132.537 176.342 1.00 149.62 ? 852  LYS A N   1 
ATOM   6076 C CA  . LYS A 1 834  ? 167.463 133.151 177.653 1.00 149.24 ? 852  LYS A CA  1 
ATOM   6077 C C   . LYS A 1 834  ? 166.581 132.288 178.547 1.00 151.82 ? 852  LYS A C   1 
ATOM   6078 O O   . LYS A 1 834  ? 165.902 131.364 178.093 1.00 150.75 ? 852  LYS A O   1 
ATOM   6079 C CB  . LYS A 1 834  ? 166.878 134.560 177.527 1.00 140.99 ? 852  LYS A CB  1 
ATOM   6080 C CG  . LYS A 1 834  ? 167.698 135.490 176.650 1.00 140.28 ? 852  LYS A CG  1 
ATOM   6081 C CD  . LYS A 1 834  ? 167.181 136.920 176.705 1.00 136.46 ? 852  LYS A CD  1 
ATOM   6082 C CE  . LYS A 1 834  ? 168.217 137.905 176.188 1.00 130.44 ? 852  LYS A CE  1 
ATOM   6083 N NZ  . LYS A 1 834  ? 167.747 139.313 176.289 1.00 131.51 ? 852  LYS A NZ  1 
ATOM   6084 N N   . ALA A 1 835  ? 166.599 132.603 179.838 1.00 154.95 ? 853  ALA A N   1 
ATOM   6085 C CA  . ALA A 1 835  ? 165.817 131.855 180.806 1.00 156.09 ? 853  ALA A CA  1 
ATOM   6086 C C   . ALA A 1 835  ? 164.359 132.301 180.783 1.00 158.65 ? 853  ALA A C   1 
ATOM   6087 O O   . ALA A 1 835  ? 164.029 133.434 180.421 1.00 156.08 ? 853  ALA A O   1 
ATOM   6088 C CB  . ALA A 1 835  ? 166.393 132.028 182.210 1.00 152.97 ? 853  ALA A CB  1 
ATOM   6089 N N   . GLU A 1 836  ? 163.481 131.386 181.184 1.00 162.16 ? 854  GLU A N   1 
ATOM   6090 C CA  . GLU A 1 836  ? 162.054 131.659 181.233 1.00 160.01 ? 854  GLU A CA  1 
ATOM   6091 C C   . GLU A 1 836  ? 161.728 132.515 182.458 1.00 158.65 ? 854  GLU A C   1 
ATOM   6092 O O   . GLU A 1 836  ? 162.614 132.992 183.171 1.00 160.00 ? 854  GLU A O   1 
ATOM   6093 C CB  . GLU A 1 836  ? 161.263 130.347 181.219 1.00 160.82 ? 854  GLU A CB  1 
ATOM   6094 C CG  . GLU A 1 836  ? 161.433 129.412 182.440 1.00 164.35 ? 854  GLU A CG  1 
ATOM   6095 C CD  . GLU A 1 836  ? 162.575 128.421 182.287 1.00 168.80 ? 854  GLU A CD  1 
ATOM   6096 O OE1 . GLU A 1 836  ? 163.462 128.649 181.437 1.00 167.97 ? 854  GLU A OE1 1 
ATOM   6097 O OE2 . GLU A 1 836  ? 162.585 127.411 183.020 1.00 170.68 ? 854  GLU A OE2 1 
ATOM   6098 N N   . GLY A 1 837  ? 160.436 132.718 182.697 1.00 157.23 ? 855  GLY A N   1 
ATOM   6099 C CA  . GLY A 1 837  ? 159.961 133.405 183.883 1.00 155.77 ? 855  GLY A CA  1 
ATOM   6100 C C   . GLY A 1 837  ? 159.762 134.891 183.654 1.00 154.64 ? 855  GLY A C   1 
ATOM   6101 O O   . GLY A 1 837  ? 159.985 135.433 182.568 1.00 151.77 ? 855  GLY A O   1 
ATOM   6102 N N   . ILE A 1 838  ? 159.332 135.550 184.727 1.00 154.64 ? 856  ILE A N   1 
ATOM   6103 C CA  . ILE A 1 838  ? 159.048 136.981 184.731 1.00 155.22 ? 856  ILE A CA  1 
ATOM   6104 C C   . ILE A 1 838  ? 160.282 137.703 185.249 1.00 151.22 ? 856  ILE A C   1 
ATOM   6105 O O   . ILE A 1 838  ? 160.821 137.345 186.303 1.00 148.29 ? 856  ILE A O   1 
ATOM   6106 C CB  . ILE A 1 838  ? 157.816 137.317 185.594 1.00 156.43 ? 856  ILE A CB  1 
ATOM   6107 C CG1 . ILE A 1 838  ? 156.743 136.217 185.510 1.00 156.12 ? 856  ILE A CG1 1 
ATOM   6108 C CG2 . ILE A 1 838  ? 157.232 138.661 185.173 1.00 154.89 ? 856  ILE A CG2 1 
ATOM   6109 C CD1 . ILE A 1 838  ? 155.458 136.555 186.241 1.00 157.01 ? 856  ILE A CD1 1 
ATOM   6110 N N   . GLU A 1 839  ? 160.732 138.712 184.508 1.00 149.54 ? 857  GLU A N   1 
ATOM   6111 C CA  . GLU A 1 839  ? 161.945 139.435 184.859 1.00 149.74 ? 857  GLU A CA  1 
ATOM   6112 C C   . GLU A 1 839  ? 161.712 140.313 186.081 1.00 144.46 ? 857  GLU A C   1 
ATOM   6113 O O   . GLU A 1 839  ? 160.661 140.950 186.210 1.00 143.31 ? 857  GLU A O   1 
ATOM   6114 C CB  . GLU A 1 839  ? 162.414 140.289 183.682 1.00 157.32 ? 857  GLU A CB  1 
ATOM   6115 C CG  . GLU A 1 839  ? 163.721 141.029 183.934 1.00 161.80 ? 857  GLU A CG  1 
ATOM   6116 C CD  . GLU A 1 839  ? 164.309 141.624 182.671 1.00 176.95 ? 857  GLU A CD  1 
ATOM   6117 O OE1 . GLU A 1 839  ? 164.948 140.876 181.903 1.00 178.56 ? 857  GLU A OE1 1 
ATOM   6118 O OE2 . GLU A 1 839  ? 164.133 142.841 182.449 1.00 185.74 ? 857  GLU A OE2 1 
ATOM   6119 N N   . LYS A 1 840  ? 162.696 140.339 186.975 1.00 141.00 ? 858  LYS A N   1 
ATOM   6120 C CA  . LYS A 1 840  ? 162.717 141.218 188.133 1.00 133.09 ? 858  LYS A CA  1 
ATOM   6121 C C   . LYS A 1 840  ? 164.095 141.850 188.236 1.00 132.21 ? 858  LYS A C   1 
ATOM   6122 O O   . LYS A 1 840  ? 165.105 141.215 187.908 1.00 132.24 ? 858  LYS A O   1 
ATOM   6123 C CB  . LYS A 1 840  ? 162.392 140.462 189.425 1.00 130.41 ? 858  LYS A CB  1 
ATOM   6124 C CG  . LYS A 1 840  ? 161.003 139.842 189.468 1.00 132.14 ? 858  LYS A CG  1 
ATOM   6125 C CD  . LYS A 1 840  ? 159.930 140.889 189.718 1.00 140.64 ? 858  LYS A CD  1 
ATOM   6126 C CE  . LYS A 1 840  ? 158.591 140.242 190.029 1.00 152.49 ? 858  LYS A CE  1 
ATOM   6127 N NZ  . LYS A 1 840  ? 157.506 141.250 190.185 1.00 158.42 ? 858  LYS A NZ  1 
ATOM   6128 N N   . SER A 1 841  ? 164.127 143.102 188.688 1.00 128.54 ? 859  SER A N   1 
ATOM   6129 C CA  . SER A 1 841  ? 165.357 143.866 188.835 1.00 119.82 ? 859  SER A CA  1 
ATOM   6130 C C   . SER A 1 841  ? 165.377 144.540 190.197 1.00 119.14 ? 859  SER A C   1 
ATOM   6131 O O   . SER A 1 841  ? 164.356 145.056 190.661 1.00 125.90 ? 859  SER A O   1 
ATOM   6132 C CB  . SER A 1 841  ? 165.492 144.919 187.732 1.00 119.88 ? 859  SER A CB  1 
ATOM   6133 O OG  . SER A 1 841  ? 164.558 145.968 187.914 1.00 133.24 ? 859  SER A OG  1 
ATOM   6134 N N   . TYR A 1 842  ? 166.547 144.525 190.829 1.00 115.66 ? 860  TYR A N   1 
ATOM   6135 C CA  . TYR A 1 842  ? 166.788 145.174 192.108 1.00 113.74 ? 860  TYR A CA  1 
ATOM   6136 C C   . TYR A 1 842  ? 168.026 146.044 191.968 1.00 114.77 ? 860  TYR A C   1 
ATOM   6137 O O   . TYR A 1 842  ? 168.981 145.663 191.288 1.00 119.77 ? 860  TYR A O   1 
ATOM   6138 C CB  . TYR A 1 842  ? 166.978 144.138 193.222 1.00 112.31 ? 860  TYR A CB  1 
ATOM   6139 C CG  . TYR A 1 842  ? 167.545 144.694 194.508 1.00 114.05 ? 860  TYR A CG  1 
ATOM   6140 C CD1 . TYR A 1 842  ? 166.742 145.387 195.401 1.00 115.21 ? 860  TYR A CD1 1 
ATOM   6141 C CD2 . TYR A 1 842  ? 168.882 144.516 194.831 1.00 112.52 ? 860  TYR A CD2 1 
ATOM   6142 C CE1 . TYR A 1 842  ? 167.257 145.892 196.578 1.00 116.60 ? 860  TYR A CE1 1 
ATOM   6143 C CE2 . TYR A 1 842  ? 169.405 145.017 196.005 1.00 111.40 ? 860  TYR A CE2 1 
ATOM   6144 C CZ  . TYR A 1 842  ? 168.589 145.702 196.875 1.00 115.41 ? 860  TYR A CZ  1 
ATOM   6145 O OH  . TYR A 1 842  ? 169.111 146.202 198.044 1.00 118.43 ? 860  TYR A OH  1 
ATOM   6146 N N   . SER A 1 843  ? 167.999 147.218 192.595 1.00 110.67 ? 861  SER A N   1 
ATOM   6147 C CA  . SER A 1 843  ? 169.102 148.166 192.519 1.00 102.05 ? 861  SER A CA  1 
ATOM   6148 C C   . SER A 1 843  ? 169.306 148.803 193.880 1.00 100.19 ? 861  SER A C   1 
ATOM   6149 O O   . SER A 1 843  ? 168.335 149.206 194.526 1.00 116.00 ? 861  SER A O   1 
ATOM   6150 C CB  . SER A 1 843  ? 168.835 149.247 191.469 1.00 109.31 ? 861  SER A CB  1 
ATOM   6151 O OG  . SER A 1 843  ? 169.215 148.805 190.179 1.00 117.12 ? 861  SER A OG  1 
ATOM   6152 N N   . GLN A 1 844  ? 170.563 148.885 194.313 1.00 90.18  ? 862  GLN A N   1 
ATOM   6153 C CA  . GLN A 1 844  ? 170.916 149.543 195.565 1.00 90.56  ? 862  GLN A CA  1 
ATOM   6154 C C   . GLN A 1 844  ? 172.135 150.422 195.344 1.00 91.97  ? 862  GLN A C   1 
ATOM   6155 O O   . GLN A 1 844  ? 173.176 149.937 194.894 1.00 99.52  ? 862  GLN A O   1 
ATOM   6156 C CB  . GLN A 1 844  ? 171.196 148.523 196.670 1.00 91.81  ? 862  GLN A CB  1 
ATOM   6157 C CG  . GLN A 1 844  ? 171.182 149.125 198.065 1.00 105.46 ? 862  GLN A CG  1 
ATOM   6158 C CD  . GLN A 1 844  ? 171.283 148.080 199.157 1.00 131.90 ? 862  GLN A CD  1 
ATOM   6159 O OE1 . GLN A 1 844  ? 171.126 146.886 198.907 1.00 136.93 ? 862  GLN A OE1 1 
ATOM   6160 N NE2 . GLN A 1 844  ? 171.547 148.527 200.380 1.00 142.01 ? 862  GLN A NE2 1 
ATOM   6161 N N   . SER A 1 845  ? 172.004 151.703 195.673 1.00 86.65  ? 863  SER A N   1 
ATOM   6162 C CA  . SER A 1 845  ? 173.065 152.685 195.511 1.00 84.76  ? 863  SER A CA  1 
ATOM   6163 C C   . SER A 1 845  ? 173.641 153.052 196.871 1.00 88.87  ? 863  SER A C   1 
ATOM   6164 O O   . SER A 1 845  ? 172.983 152.901 197.903 1.00 99.53  ? 863  SER A O   1 
ATOM   6165 C CB  . SER A 1 845  ? 172.546 153.945 194.816 1.00 91.74  ? 863  SER A CB  1 
ATOM   6166 O OG  . SER A 1 845  ? 171.688 153.615 193.739 1.00 104.50 ? 863  SER A OG  1 
ATOM   6167 N N   . ILE A 1 846  ? 174.881 153.528 196.861 1.00 85.50  ? 864  ILE A N   1 
ATOM   6168 C CA  . ILE A 1 846  ? 175.551 153.965 198.080 1.00 82.26  ? 864  ILE A CA  1 
ATOM   6169 C C   . ILE A 1 846  ? 176.577 155.019 197.696 1.00 82.93  ? 864  ILE A C   1 
ATOM   6170 O O   . ILE A 1 846  ? 177.314 154.863 196.717 1.00 90.71  ? 864  ILE A O   1 
ATOM   6171 C CB  . ILE A 1 846  ? 176.193 152.772 198.833 1.00 79.51  ? 864  ILE A CB  1 
ATOM   6172 C CG1 . ILE A 1 846  ? 176.922 153.215 200.112 1.00 89.84  ? 864  ILE A CG1 1 
ATOM   6173 C CG2 . ILE A 1 846  ? 177.180 152.013 197.949 1.00 81.87  ? 864  ILE A CG2 1 
ATOM   6174 C CD1 . ILE A 1 846  ? 176.040 153.905 201.135 1.00 94.63  ? 864  ILE A CD1 1 
ATOM   6175 N N   . LEU A 1 847  ? 176.621 156.092 198.478 1.00 85.08  ? 865  LEU A N   1 
ATOM   6176 C CA  . LEU A 1 847  ? 177.533 157.204 198.255 1.00 88.30  ? 865  LEU A CA  1 
ATOM   6177 C C   . LEU A 1 847  ? 178.716 157.050 199.202 1.00 95.70  ? 865  LEU A C   1 
ATOM   6178 O O   . LEU A 1 847  ? 178.536 157.031 200.424 1.00 99.82  ? 865  LEU A O   1 
ATOM   6179 C CB  . LEU A 1 847  ? 176.820 158.537 198.487 1.00 92.98  ? 865  LEU A CB  1 
ATOM   6180 C CG  . LEU A 1 847  ? 177.397 159.816 197.867 1.00 89.37  ? 865  LEU A CG  1 
ATOM   6181 C CD1 . LEU A 1 847  ? 176.363 160.943 197.938 1.00 105.18 ? 865  LEU A CD1 1 
ATOM   6182 C CD2 . LEU A 1 847  ? 178.700 160.244 198.524 1.00 90.99  ? 865  LEU A CD2 1 
ATOM   6183 N N   . LEU A 1 848  ? 179.916 156.943 198.637 1.00 103.15 ? 866  LEU A N   1 
ATOM   6184 C CA  . LEU A 1 848  ? 181.156 156.922 199.401 1.00 104.43 ? 866  LEU A CA  1 
ATOM   6185 C C   . LEU A 1 848  ? 181.748 158.324 199.362 1.00 106.91 ? 866  LEU A C   1 
ATOM   6186 O O   . LEU A 1 848  ? 182.123 158.813 198.289 1.00 105.81 ? 866  LEU A O   1 
ATOM   6187 C CB  . LEU A 1 848  ? 182.128 155.890 198.832 1.00 97.53  ? 866  LEU A CB  1 
ATOM   6188 C CG  . LEU A 1 848  ? 181.553 154.472 198.741 1.00 93.45  ? 866  LEU A CG  1 
ATOM   6189 C CD1 . LEU A 1 848  ? 181.360 154.057 197.294 1.00 87.62  ? 866  LEU A CD1 1 
ATOM   6190 C CD2 . LEU A 1 848  ? 182.438 153.476 199.465 1.00 103.56 ? 866  LEU A CD2 1 
ATOM   6191 N N   . ASP A 1 849  ? 181.834 158.960 200.529 1.00 108.56 ? 867  ASP A N   1 
ATOM   6192 C CA  . ASP A 1 849  ? 182.084 160.395 200.659 1.00 111.16 ? 867  ASP A CA  1 
ATOM   6193 C C   . ASP A 1 849  ? 183.436 160.621 201.327 1.00 120.11 ? 867  ASP A C   1 
ATOM   6194 O O   . ASP A 1 849  ? 183.520 160.735 202.552 1.00 127.48 ? 867  ASP A O   1 
ATOM   6195 C CB  . ASP A 1 849  ? 180.958 161.051 201.459 1.00 115.89 ? 867  ASP A CB  1 
ATOM   6196 C CG  . ASP A 1 849  ? 181.004 162.562 201.406 1.00 123.58 ? 867  ASP A CG  1 
ATOM   6197 O OD1 . ASP A 1 849  ? 181.821 163.111 200.638 1.00 124.28 ? 867  ASP A OD1 1 
ATOM   6198 O OD2 . ASP A 1 849  ? 180.219 163.205 202.133 1.00 125.36 ? 867  ASP A OD2 1 
ATOM   6199 N N   . LEU A 1 850  ? 184.494 160.690 200.517 1.00 120.30 ? 868  LEU A N   1 
ATOM   6200 C CA  . LEU A 1 850  ? 185.837 161.000 200.987 1.00 124.47 ? 868  LEU A CA  1 
ATOM   6201 C C   . LEU A 1 850  ? 186.192 162.464 200.753 1.00 131.95 ? 868  LEU A C   1 
ATOM   6202 O O   . LEU A 1 850  ? 187.360 162.788 200.513 1.00 136.13 ? 868  LEU A O   1 
ATOM   6203 C CB  . LEU A 1 850  ? 186.858 160.097 200.299 1.00 123.05 ? 868  LEU A CB  1 
ATOM   6204 C CG  . LEU A 1 850  ? 186.615 158.589 200.369 1.00 119.58 ? 868  LEU A CG  1 
ATOM   6205 C CD1 . LEU A 1 850  ? 187.413 157.897 199.292 1.00 117.52 ? 868  LEU A CD1 1 
ATOM   6206 C CD2 . LEU A 1 850  ? 186.978 158.047 201.739 1.00 127.47 ? 868  LEU A CD2 1 
ATOM   6207 N N   . THR A 1 851  ? 185.197 163.356 200.778 1.00 131.35 ? 869  THR A N   1 
ATOM   6208 C CA  . THR A 1 851  ? 185.498 164.781 200.715 1.00 140.37 ? 869  THR A CA  1 
ATOM   6209 C C   . THR A 1 851  ? 186.180 165.251 201.990 1.00 151.03 ? 869  THR A C   1 
ATOM   6210 O O   . THR A 1 851  ? 187.089 166.087 201.937 1.00 155.42 ? 869  THR A O   1 
ATOM   6211 C CB  . THR A 1 851  ? 184.225 165.598 200.487 1.00 133.98 ? 869  THR A CB  1 
ATOM   6212 O OG1 . THR A 1 851  ? 183.194 165.136 201.366 1.00 130.96 ? 869  THR A OG1 1 
ATOM   6213 C CG2 . THR A 1 851  ? 183.748 165.473 199.047 1.00 131.98 ? 869  THR A CG2 1 
ATOM   6214 N N   . ASP A 1 852  ? 185.755 164.730 203.136 1.00 150.82 ? 870  ASP A N   1 
ATOM   6215 C CA  . ASP A 1 852  ? 186.387 165.079 204.398 1.00 163.48 ? 870  ASP A CA  1 
ATOM   6216 C C   . ASP A 1 852  ? 187.796 164.505 204.444 1.00 166.76 ? 870  ASP A C   1 
ATOM   6217 O O   . ASP A 1 852  ? 188.005 163.317 204.179 1.00 159.86 ? 870  ASP A O   1 
ATOM   6218 C CB  . ASP A 1 852  ? 185.556 164.549 205.567 1.00 171.40 ? 870  ASP A CB  1 
ATOM   6219 C CG  . ASP A 1 852  ? 186.009 165.099 206.907 1.00 180.06 ? 870  ASP A CG  1 
ATOM   6220 O OD1 . ASP A 1 852  ? 186.651 166.170 206.936 1.00 182.41 ? 870  ASP A OD1 1 
ATOM   6221 O OD2 . ASP A 1 852  ? 185.722 164.454 207.938 1.00 180.98 ? 870  ASP A OD2 1 
ATOM   6222 N N   . ASN A 1 853  ? 188.765 165.352 204.781 1.00 174.79 ? 871  ASN A N   1 
ATOM   6223 C CA  . ASN A 1 853  ? 190.159 164.934 204.837 1.00 176.14 ? 871  ASN A CA  1 
ATOM   6224 C C   . ASN A 1 853  ? 190.512 164.206 206.128 1.00 180.89 ? 871  ASN A C   1 
ATOM   6225 O O   . ASN A 1 853  ? 191.619 163.665 206.225 1.00 180.39 ? 871  ASN A O   1 
ATOM   6226 C CB  . ASN A 1 853  ? 191.081 166.150 204.668 1.00 179.31 ? 871  ASN A CB  1 
ATOM   6227 C CG  . ASN A 1 853  ? 191.531 166.359 203.229 1.00 172.14 ? 871  ASN A CG  1 
ATOM   6228 O OD1 . ASN A 1 853  ? 191.813 165.405 202.501 1.00 170.04 ? 871  ASN A OD1 1 
ATOM   6229 N ND2 . ASN A 1 853  ? 191.594 167.617 202.812 1.00 169.05 ? 871  ASN A ND2 1 
ATOM   6230 N N   . ARG A 1 854  ? 189.615 164.180 207.117 1.00 184.59 ? 872  ARG A N   1 
ATOM   6231 C CA  . ARG A 1 854  ? 189.910 163.466 208.355 1.00 185.44 ? 872  ARG A CA  1 
ATOM   6232 C C   . ARG A 1 854  ? 190.035 161.968 208.104 1.00 177.70 ? 872  ARG A C   1 
ATOM   6233 O O   . ARG A 1 854  ? 190.949 161.321 208.629 1.00 175.39 ? 872  ARG A O   1 
ATOM   6234 C CB  . ARG A 1 854  ? 188.830 163.743 209.405 1.00 186.35 ? 872  ARG A CB  1 
ATOM   6235 C CG  . ARG A 1 854  ? 188.534 165.222 209.657 1.00 188.42 ? 872  ARG A CG  1 
ATOM   6236 C CD  . ARG A 1 854  ? 189.751 165.965 210.184 1.00 191.73 ? 872  ARG A CD  1 
ATOM   6237 N NE  . ARG A 1 854  ? 190.509 166.596 209.108 1.00 191.74 ? 872  ARG A NE  1 
ATOM   6238 C CZ  . ARG A 1 854  ? 190.156 167.708 208.473 1.00 191.69 ? 872  ARG A CZ  1 
ATOM   6239 N NH1 . ARG A 1 854  ? 189.039 168.357 208.768 1.00 191.49 ? 872  ARG A NH1 1 
ATOM   6240 N NH2 . ARG A 1 854  ? 190.943 168.181 207.511 1.00 191.54 ? 872  ARG A NH2 1 
ATOM   6241 N N   . LEU A 1 855  ? 189.131 161.408 207.302 1.00 170.67 ? 873  LEU A N   1 
ATOM   6242 C CA  . LEU A 1 855  ? 189.175 160.016 206.884 1.00 159.62 ? 873  LEU A CA  1 
ATOM   6243 C C   . LEU A 1 855  ? 189.617 159.939 205.428 1.00 159.94 ? 873  LEU A C   1 
ATOM   6244 O O   . LEU A 1 855  ? 189.352 160.846 204.634 1.00 161.35 ? 873  LEU A O   1 
ATOM   6245 C CB  . LEU A 1 855  ? 187.808 159.338 207.079 1.00 150.64 ? 873  LEU A CB  1 
ATOM   6246 C CG  . LEU A 1 855  ? 186.718 159.391 205.999 1.00 151.40 ? 873  LEU A CG  1 
ATOM   6247 C CD1 . LEU A 1 855  ? 185.546 158.514 206.408 1.00 147.54 ? 873  LEU A CD1 1 
ATOM   6248 C CD2 . LEU A 1 855  ? 186.255 160.815 205.751 1.00 153.84 ? 873  LEU A CD2 1 
ATOM   6249 N N   . GLN A 1 856  ? 190.308 158.845 205.096 1.00 154.80 ? 874  GLN A N   1 
ATOM   6250 C CA  . GLN A 1 856  ? 190.812 158.597 203.752 1.00 149.57 ? 874  GLN A CA  1 
ATOM   6251 C C   . GLN A 1 856  ? 190.353 157.273 203.161 1.00 139.41 ? 874  GLN A C   1 
ATOM   6252 O O   . GLN A 1 856  ? 190.606 157.034 201.975 1.00 135.32 ? 874  GLN A O   1 
ATOM   6253 C CB  . GLN A 1 856  ? 192.349 158.631 203.744 1.00 152.97 ? 874  GLN A CB  1 
ATOM   6254 C CG  . GLN A 1 856  ? 192.965 159.975 204.126 1.00 163.57 ? 874  GLN A CG  1 
ATOM   6255 C CD  . GLN A 1 856  ? 192.550 161.105 203.200 1.00 166.72 ? 874  GLN A CD  1 
ATOM   6256 O OE1 . GLN A 1 856  ? 192.830 161.073 202.002 1.00 162.27 ? 874  GLN A OE1 1 
ATOM   6257 N NE2 . GLN A 1 856  ? 191.877 162.109 203.751 1.00 168.01 ? 874  GLN A NE2 1 
ATOM   6258 N N   . SER A 1 857  ? 189.705 156.409 203.942 1.00 138.55 ? 875  SER A N   1 
ATOM   6259 C CA  . SER A 1 857  ? 189.139 155.163 203.451 1.00 132.93 ? 875  SER A CA  1 
ATOM   6260 C C   . SER A 1 857  ? 187.717 155.029 203.971 1.00 134.94 ? 875  SER A C   1 
ATOM   6261 O O   . SER A 1 857  ? 187.399 155.479 205.074 1.00 134.21 ? 875  SER A O   1 
ATOM   6262 C CB  . SER A 1 857  ? 189.969 153.952 203.887 1.00 128.93 ? 875  SER A CB  1 
ATOM   6263 O OG  . SER A 1 857  ? 189.432 153.365 205.059 1.00 137.36 ? 875  SER A OG  1 
ATOM   6264 N N   . THR A 1 858  ? 186.861 154.413 203.158 1.00 131.14 ? 876  THR A N   1 
ATOM   6265 C CA  . THR A 1 858  ? 185.458 154.217 203.511 1.00 124.54 ? 876  THR A CA  1 
ATOM   6266 C C   . THR A 1 858  ? 185.004 152.868 202.981 1.00 117.18 ? 876  THR A C   1 
ATOM   6267 O O   . THR A 1 858  ? 185.056 152.630 201.771 1.00 118.01 ? 876  THR A O   1 
ATOM   6268 C CB  . THR A 1 858  ? 184.584 155.337 202.943 1.00 126.88 ? 876  THR A CB  1 
ATOM   6269 O OG1 . THR A 1 858  ? 184.993 156.593 203.498 1.00 130.29 ? 876  THR A OG1 1 
ATOM   6270 C CG2 . THR A 1 858  ? 183.120 155.095 203.276 1.00 127.64 ? 876  THR A CG2 1 
ATOM   6271 N N   . LEU A 1 859  ? 184.550 152.002 203.883 1.00 111.22 ? 877  LEU A N   1 
ATOM   6272 C CA  . LEU A 1 859  ? 184.059 150.672 203.549 1.00 108.83 ? 877  LEU A CA  1 
ATOM   6273 C C   . LEU A 1 859  ? 182.540 150.675 203.636 1.00 111.63 ? 877  LEU A C   1 
ATOM   6274 O O   . LEU A 1 859  ? 181.970 151.219 204.588 1.00 115.49 ? 877  LEU A O   1 
ATOM   6275 C CB  . LEU A 1 859  ? 184.648 149.620 204.497 1.00 106.83 ? 877  LEU A CB  1 
ATOM   6276 C CG  . LEU A 1 859  ? 184.196 148.153 204.405 1.00 112.76 ? 877  LEU A CG  1 
ATOM   6277 C CD1 . LEU A 1 859  ? 185.125 147.359 203.503 1.00 113.21 ? 877  LEU A CD1 1 
ATOM   6278 C CD2 . LEU A 1 859  ? 184.132 147.528 205.788 1.00 120.00 ? 877  LEU A CD2 1 
ATOM   6279 N N   . LYS A 1 860  ? 181.894 150.074 202.641 1.00 111.04 ? 878  LYS A N   1 
ATOM   6280 C CA  . LYS A 1 860  ? 180.456 149.862 202.634 1.00 108.79 ? 878  LYS A CA  1 
ATOM   6281 C C   . LYS A 1 860  ? 180.188 148.427 202.207 1.00 113.19 ? 878  LYS A C   1 
ATOM   6282 O O   . LYS A 1 860  ? 181.037 147.778 201.596 1.00 116.33 ? 878  LYS A O   1 
ATOM   6283 C CB  . LYS A 1 860  ? 179.735 150.833 201.688 1.00 103.52 ? 878  LYS A CB  1 
ATOM   6284 C CG  . LYS A 1 860  ? 179.943 152.306 202.009 1.00 104.36 ? 878  LYS A CG  1 
ATOM   6285 C CD  . LYS A 1 860  ? 179.132 152.731 203.218 1.00 117.15 ? 878  LYS A CD  1 
ATOM   6286 C CE  . LYS A 1 860  ? 179.271 154.221 203.480 1.00 127.74 ? 878  LYS A CE  1 
ATOM   6287 N NZ  . LYS A 1 860  ? 178.711 154.609 204.803 1.00 141.05 ? 878  LYS A NZ  1 
ATOM   6288 N N   . THR A 1 861  ? 179.003 147.933 202.551 1.00 116.62 ? 879  THR A N   1 
ATOM   6289 C CA  . THR A 1 861  ? 178.570 146.587 202.201 1.00 118.32 ? 879  THR A CA  1 
ATOM   6290 C C   . THR A 1 861  ? 177.242 146.673 201.468 1.00 111.93 ? 879  THR A C   1 
ATOM   6291 O O   . THR A 1 861  ? 176.317 147.345 201.936 1.00 111.93 ? 879  THR A O   1 
ATOM   6292 C CB  . THR A 1 861  ? 178.426 145.709 203.447 1.00 123.95 ? 879  THR A CB  1 
ATOM   6293 O OG1 . THR A 1 861  ? 179.541 145.927 204.320 1.00 128.18 ? 879  THR A OG1 1 
ATOM   6294 C CG2 . THR A 1 861  ? 178.366 144.236 203.064 1.00 120.16 ? 879  THR A CG2 1 
ATOM   6295 N N   . LEU A 1 862  ? 177.156 146.001 200.321 1.00 113.55 ? 880  LEU A N   1 
ATOM   6296 C CA  . LEU A 1 862  ? 175.925 145.908 199.545 1.00 113.07 ? 880  LEU A CA  1 
ATOM   6297 C C   . LEU A 1 862  ? 175.575 144.439 199.380 1.00 119.62 ? 880  LEU A C   1 
ATOM   6298 O O   . LEU A 1 862  ? 176.395 143.657 198.890 1.00 127.98 ? 880  LEU A O   1 
ATOM   6299 C CB  . LEU A 1 862  ? 176.074 146.577 198.174 1.00 100.98 ? 880  LEU A CB  1 
ATOM   6300 C CG  . LEU A 1 862  ? 176.049 148.108 198.084 1.00 89.88  ? 880  LEU A CG  1 
ATOM   6301 C CD1 . LEU A 1 862  ? 176.137 148.530 196.631 1.00 87.31  ? 880  LEU A CD1 1 
ATOM   6302 C CD2 . LEU A 1 862  ? 174.807 148.713 198.722 1.00 97.55  ? 880  LEU A CD2 1 
ATOM   6303 N N   . SER A 1 863  ? 174.356 144.075 199.780 1.00 118.14 ? 881  SER A N   1 
ATOM   6304 C CA  . SER A 1 863  ? 173.935 142.683 199.837 1.00 122.64 ? 881  SER A CA  1 
ATOM   6305 C C   . SER A 1 863  ? 172.534 142.537 199.265 1.00 127.66 ? 881  SER A C   1 
ATOM   6306 O O   . SER A 1 863  ? 171.730 143.471 199.290 1.00 133.47 ? 881  SER A O   1 
ATOM   6307 C CB  . SER A 1 863  ? 173.963 142.151 201.275 1.00 125.06 ? 881  SER A CB  1 
ATOM   6308 O OG  . SER A 1 863  ? 173.083 142.886 202.106 1.00 124.11 ? 881  SER A OG  1 
ATOM   6309 N N   . PHE A 1 864  ? 172.261 141.344 198.743 1.00 127.52 ? 882  PHE A N   1 
ATOM   6310 C CA  . PHE A 1 864  ? 170.949 140.993 198.223 1.00 127.06 ? 882  PHE A CA  1 
ATOM   6311 C C   . PHE A 1 864  ? 170.836 139.477 198.201 1.00 133.01 ? 882  PHE A C   1 
ATOM   6312 O O   . PHE A 1 864  ? 171.802 138.785 197.869 1.00 135.42 ? 882  PHE A O   1 
ATOM   6313 C CB  . PHE A 1 864  ? 170.727 141.561 196.817 1.00 118.19 ? 882  PHE A CB  1 
ATOM   6314 C CG  . PHE A 1 864  ? 169.445 141.110 196.181 1.00 119.93 ? 882  PHE A CG  1 
ATOM   6315 C CD1 . PHE A 1 864  ? 168.236 141.659 196.567 1.00 123.22 ? 882  PHE A CD1 1 
ATOM   6316 C CD2 . PHE A 1 864  ? 169.448 140.132 195.202 1.00 124.98 ? 882  PHE A CD2 1 
ATOM   6317 C CE1 . PHE A 1 864  ? 167.054 141.246 195.984 1.00 129.08 ? 882  PHE A CE1 1 
ATOM   6318 C CE2 . PHE A 1 864  ? 168.270 139.714 194.616 1.00 131.16 ? 882  PHE A CE2 1 
ATOM   6319 C CZ  . PHE A 1 864  ? 167.071 140.272 195.008 1.00 132.72 ? 882  PHE A CZ  1 
ATOM   6320 N N   . SER A 1 865  ? 169.655 138.974 198.558 1.00 133.70 ? 883  SER A N   1 
ATOM   6321 C CA  . SER A 1 865  ? 169.360 137.548 198.579 1.00 138.67 ? 883  SER A CA  1 
ATOM   6322 C C   . SER A 1 865  ? 168.262 137.260 197.568 1.00 139.77 ? 883  SER A C   1 
ATOM   6323 O O   . SER A 1 865  ? 167.250 137.967 197.528 1.00 140.45 ? 883  SER A O   1 
ATOM   6324 C CB  . SER A 1 865  ? 168.928 137.098 199.976 1.00 144.67 ? 883  SER A CB  1 
ATOM   6325 O OG  . SER A 1 865  ? 169.918 137.414 200.939 1.00 143.86 ? 883  SER A OG  1 
ATOM   6326 N N   . PHE A 1 866  ? 168.463 136.227 196.758 1.00 142.46 ? 884  PHE A N   1 
ATOM   6327 C CA  . PHE A 1 866  ? 167.492 135.910 195.726 1.00 145.03 ? 884  PHE A CA  1 
ATOM   6328 C C   . PHE A 1 866  ? 166.265 135.236 196.346 1.00 148.62 ? 884  PHE A C   1 
ATOM   6329 O O   . PHE A 1 866  ? 166.377 134.576 197.383 1.00 149.91 ? 884  PHE A O   1 
ATOM   6330 C CB  . PHE A 1 866  ? 168.112 134.990 194.682 1.00 148.47 ? 884  PHE A CB  1 
ATOM   6331 C CG  . PHE A 1 866  ? 169.117 135.670 193.800 1.00 143.89 ? 884  PHE A CG  1 
ATOM   6332 C CD1 . PHE A 1 866  ? 168.724 136.297 192.632 1.00 138.96 ? 884  PHE A CD1 1 
ATOM   6333 C CD2 . PHE A 1 866  ? 170.458 135.683 194.141 1.00 142.48 ? 884  PHE A CD2 1 
ATOM   6334 C CE1 . PHE A 1 866  ? 169.649 136.923 191.822 1.00 133.33 ? 884  PHE A CE1 1 
ATOM   6335 C CE2 . PHE A 1 866  ? 171.386 136.307 193.334 1.00 139.29 ? 884  PHE A CE2 1 
ATOM   6336 C CZ  . PHE A 1 866  ? 170.980 136.928 192.173 1.00 130.68 ? 884  PHE A CZ  1 
ATOM   6337 N N   . PRO A 1 867  ? 165.076 135.375 195.744 1.00 148.76 ? 885  PRO A N   1 
ATOM   6338 C CA  . PRO A 1 867  ? 163.925 134.635 196.258 1.00 155.44 ? 885  PRO A CA  1 
ATOM   6339 C C   . PRO A 1 867  ? 164.105 133.146 196.044 1.00 159.13 ? 885  PRO A C   1 
ATOM   6340 O O   . PRO A 1 867  ? 164.916 132.720 195.202 1.00 158.24 ? 885  PRO A O   1 
ATOM   6341 C CB  . PRO A 1 867  ? 162.750 135.183 195.426 1.00 151.14 ? 885  PRO A CB  1 
ATOM   6342 C CG  . PRO A 1 867  ? 163.200 136.487 194.938 1.00 142.10 ? 885  PRO A CG  1 
ATOM   6343 C CD  . PRO A 1 867  ? 164.663 136.337 194.704 1.00 139.75 ? 885  PRO A CD  1 
ATOM   6344 N N   . PRO A 1 868  ? 163.383 132.303 196.793 1.00 162.01 ? 886  PRO A N   1 
ATOM   6345 C CA  . PRO A 1 868  ? 163.516 130.852 196.584 1.00 164.50 ? 886  PRO A CA  1 
ATOM   6346 C C   . PRO A 1 868  ? 163.052 130.385 195.216 1.00 164.72 ? 886  PRO A C   1 
ATOM   6347 O O   . PRO A 1 868  ? 163.571 129.377 194.720 1.00 164.62 ? 886  PRO A O   1 
ATOM   6348 C CB  . PRO A 1 868  ? 162.648 130.254 197.698 1.00 167.17 ? 886  PRO A CB  1 
ATOM   6349 C CG  . PRO A 1 868  ? 161.649 131.306 197.997 1.00 164.79 ? 886  PRO A CG  1 
ATOM   6350 C CD  . PRO A 1 868  ? 162.356 132.614 197.804 1.00 159.42 ? 886  PRO A CD  1 
ATOM   6351 N N   . ASN A 1 869  ? 162.101 131.082 194.590 1.00 163.06 ? 887  ASN A N   1 
ATOM   6352 C CA  . ASN A 1 869  ? 161.523 130.669 193.316 1.00 161.78 ? 887  ASN A CA  1 
ATOM   6353 C C   . ASN A 1 869  ? 162.231 131.302 192.122 1.00 161.42 ? 887  ASN A C   1 
ATOM   6354 O O   . ASN A 1 869  ? 161.630 131.451 191.052 1.00 159.64 ? 887  ASN A O   1 
ATOM   6355 C CB  . ASN A 1 869  ? 160.032 131.005 193.280 1.00 162.70 ? 887  ASN A CB  1 
ATOM   6356 C CG  . ASN A 1 869  ? 159.768 132.496 193.340 1.00 166.23 ? 887  ASN A CG  1 
ATOM   6357 O OD1 . ASN A 1 869  ? 160.568 133.256 193.885 1.00 166.84 ? 887  ASN A OD1 1 
ATOM   6358 N ND2 . ASN A 1 869  ? 158.644 132.923 192.778 1.00 160.71 ? 887  ASN A ND2 1 
ATOM   6359 N N   . THR A 1 870  ? 163.497 131.678 192.280 1.00 160.24 ? 888  THR A N   1 
ATOM   6360 C CA  . THR A 1 870  ? 164.243 132.262 191.175 1.00 156.00 ? 888  THR A CA  1 
ATOM   6361 C C   . THR A 1 870  ? 164.564 131.201 190.131 1.00 151.05 ? 888  THR A C   1 
ATOM   6362 O O   . THR A 1 870  ? 164.806 130.037 190.458 1.00 150.20 ? 888  THR A O   1 
ATOM   6363 C CB  . THR A 1 870  ? 165.537 132.900 191.679 1.00 152.86 ? 888  THR A CB  1 
ATOM   6364 O OG1 . THR A 1 870  ? 165.277 133.643 192.877 1.00 155.13 ? 888  THR A OG1 1 
ATOM   6365 C CG2 . THR A 1 870  ? 166.128 133.825 190.626 1.00 147.24 ? 888  THR A CG2 1 
ATOM   6366 N N   . VAL A 1 871  ? 164.564 131.614 188.864 1.00 148.76 ? 889  VAL A N   1 
ATOM   6367 C CA  . VAL A 1 871  ? 164.917 130.705 187.782 1.00 147.05 ? 889  VAL A CA  1 
ATOM   6368 C C   . VAL A 1 871  ? 166.429 130.539 187.750 1.00 141.96 ? 889  VAL A C   1 
ATOM   6369 O O   . VAL A 1 871  ? 167.177 131.521 187.657 1.00 141.92 ? 889  VAL A O   1 
ATOM   6370 C CB  . VAL A 1 871  ? 164.383 131.227 186.440 1.00 149.12 ? 889  VAL A CB  1 
ATOM   6371 C CG1 . VAL A 1 871  ? 164.790 130.290 185.305 1.00 149.30 ? 889  VAL A CG1 1 
ATOM   6372 C CG2 . VAL A 1 871  ? 162.863 131.391 186.493 1.00 153.28 ? 889  VAL A CG2 1 
ATOM   6373 N N   . THR A 1 872  ? 166.886 129.292 187.832 1.00 139.29 ? 890  THR A N   1 
ATOM   6374 C CA  . THR A 1 872  ? 168.316 129.019 187.851 1.00 142.95 ? 890  THR A CA  1 
ATOM   6375 C C   . THR A 1 872  ? 168.957 129.425 186.530 1.00 146.84 ? 890  THR A C   1 
ATOM   6376 O O   . THR A 1 872  ? 168.394 129.208 185.454 1.00 150.59 ? 890  THR A O   1 
ATOM   6377 C CB  . THR A 1 872  ? 168.586 127.536 188.131 1.00 146.33 ? 890  THR A CB  1 
ATOM   6378 O OG1 . THR A 1 872  ? 170.000 127.309 188.161 1.00 152.99 ? 890  THR A OG1 1 
ATOM   6379 C CG2 . THR A 1 872  ? 167.963 126.621 187.061 1.00 145.42 ? 890  THR A CG2 1 
ATOM   6380 N N   . GLY A 1 873  ? 170.143 130.020 186.621 1.00 145.43 ? 891  GLY A N   1 
ATOM   6381 C CA  . GLY A 1 873  ? 170.870 130.465 185.452 1.00 143.90 ? 891  GLY A CA  1 
ATOM   6382 C C   . GLY A 1 873  ? 170.434 131.800 184.891 1.00 140.25 ? 891  GLY A C   1 
ATOM   6383 O O   . GLY A 1 873  ? 171.052 132.274 183.929 1.00 137.89 ? 891  GLY A O   1 
ATOM   6384 N N   . SER A 1 874  ? 169.403 132.426 185.458 1.00 138.88 ? 892  SER A N   1 
ATOM   6385 C CA  . SER A 1 874  ? 168.903 133.713 184.996 1.00 134.15 ? 892  SER A CA  1 
ATOM   6386 C C   . SER A 1 874  ? 169.477 134.891 185.770 1.00 128.13 ? 892  SER A C   1 
ATOM   6387 O O   . SER A 1 874  ? 169.066 136.029 185.527 1.00 129.26 ? 892  SER A O   1 
ATOM   6388 C CB  . SER A 1 874  ? 167.376 133.744 185.094 1.00 135.57 ? 892  SER A CB  1 
ATOM   6389 O OG  . SER A 1 874  ? 166.960 134.001 186.423 1.00 133.17 ? 892  SER A OG  1 
ATOM   6390 N N   . GLU A 1 875  ? 170.414 134.656 186.684 1.00 126.41 ? 893  GLU A N   1 
ATOM   6391 C CA  . GLU A 1 875  ? 170.913 135.701 187.565 1.00 124.89 ? 893  GLU A CA  1 
ATOM   6392 C C   . GLU A 1 875  ? 172.064 136.441 186.898 1.00 120.99 ? 893  GLU A C   1 
ATOM   6393 O O   . GLU A 1 875  ? 172.995 135.818 186.379 1.00 127.60 ? 893  GLU A O   1 
ATOM   6394 C CB  . GLU A 1 875  ? 171.373 135.106 188.896 1.00 130.00 ? 893  GLU A CB  1 
ATOM   6395 C CG  . GLU A 1 875  ? 170.377 134.149 189.532 1.00 143.29 ? 893  GLU A CG  1 
ATOM   6396 C CD  . GLU A 1 875  ? 170.625 132.703 189.149 1.00 152.89 ? 893  GLU A CD  1 
ATOM   6397 O OE1 . GLU A 1 875  ? 170.966 132.450 187.974 1.00 145.07 ? 893  GLU A OE1 1 
ATOM   6398 O OE2 . GLU A 1 875  ? 170.480 131.821 190.021 1.00 164.93 ? 893  GLU A OE2 1 
ATOM   6399 N N   . ARG A 1 876  ? 171.985 137.769 186.908 1.00 111.95 ? 894  ARG A N   1 
ATOM   6400 C CA  . ARG A 1 876  ? 173.049 138.644 186.439 1.00 107.79 ? 894  ARG A CA  1 
ATOM   6401 C C   . ARG A 1 876  ? 173.305 139.691 187.507 1.00 108.49 ? 894  ARG A C   1 
ATOM   6402 O O   . ARG A 1 876  ? 172.365 140.346 187.973 1.00 112.56 ? 894  ARG A O   1 
ATOM   6403 C CB  . ARG A 1 876  ? 172.681 139.322 185.118 1.00 106.82 ? 894  ARG A CB  1 
ATOM   6404 C CG  . ARG A 1 876  ? 172.621 138.381 183.927 1.00 114.10 ? 894  ARG A CG  1 
ATOM   6405 C CD  . ARG A 1 876  ? 171.845 138.990 182.767 1.00 117.70 ? 894  ARG A CD  1 
ATOM   6406 N NE  . ARG A 1 876  ? 172.089 140.428 182.651 1.00 116.94 ? 894  ARG A NE  1 
ATOM   6407 C CZ  . ARG A 1 876  ? 171.178 141.369 182.422 1.00 116.91 ? 894  ARG A CZ  1 
ATOM   6408 N NH1 . ARG A 1 876  ? 169.903 141.081 182.204 1.00 112.31 ? 894  ARG A NH1 1 
ATOM   6409 N NH2 . ARG A 1 876  ? 171.559 142.643 182.403 1.00 118.64 ? 894  ARG A NH2 1 
ATOM   6410 N N   . VAL A 1 877  ? 174.570 139.846 187.889 1.00 106.12 ? 895  VAL A N   1 
ATOM   6411 C CA  . VAL A 1 877  ? 174.989 140.786 188.923 1.00 101.39 ? 895  VAL A CA  1 
ATOM   6412 C C   . VAL A 1 877  ? 175.948 141.775 188.283 1.00 98.43  ? 895  VAL A C   1 
ATOM   6413 O O   . VAL A 1 877  ? 177.045 141.395 187.852 1.00 108.90 ? 895  VAL A O   1 
ATOM   6414 C CB  . VAL A 1 877  ? 175.654 140.073 190.112 1.00 106.14 ? 895  VAL A CB  1 
ATOM   6415 C CG1 . VAL A 1 877  ? 176.137 141.091 191.140 1.00 99.92  ? 895  VAL A CG1 1 
ATOM   6416 C CG2 . VAL A 1 877  ? 174.693 139.076 190.750 1.00 115.16 ? 895  VAL A CG2 1 
ATOM   6417 N N   . GLN A 1 878  ? 175.537 143.038 188.226 1.00 87.71  ? 896  GLN A N   1 
ATOM   6418 C CA  . GLN A 1 878  ? 176.358 144.126 187.726 1.00 89.43  ? 896  GLN A CA  1 
ATOM   6419 C C   . GLN A 1 878  ? 176.630 145.093 188.866 1.00 91.90  ? 896  GLN A C   1 
ATOM   6420 O O   . GLN A 1 878  ? 175.807 145.252 189.771 1.00 102.72 ? 896  GLN A O   1 
ATOM   6421 C CB  . GLN A 1 878  ? 175.665 144.860 186.576 1.00 96.79  ? 896  GLN A CB  1 
ATOM   6422 C CG  . GLN A 1 878  ? 176.614 145.396 185.518 1.00 109.86 ? 896  GLN A CG  1 
ATOM   6423 C CD  . GLN A 1 878  ? 175.950 146.384 184.580 1.00 118.13 ? 896  GLN A CD  1 
ATOM   6424 O OE1 . GLN A 1 878  ? 175.082 147.157 184.984 1.00 122.07 ? 896  GLN A OE1 1 
ATOM   6425 N NE2 . GLN A 1 878  ? 176.353 146.359 183.316 1.00 120.63 ? 896  GLN A NE2 1 
ATOM   6426 N N   . ILE A 1 879  ? 177.800 145.723 188.830 1.00 89.68  ? 897  ILE A N   1 
ATOM   6427 C CA  . ILE A 1 879  ? 178.150 146.781 189.767 1.00 83.26  ? 897  ILE A CA  1 
ATOM   6428 C C   . ILE A 1 879  ? 178.757 147.922 188.968 1.00 83.49  ? 897  ILE A C   1 
ATOM   6429 O O   . ILE A 1 879  ? 179.674 147.706 188.168 1.00 94.20  ? 897  ILE A O   1 
ATOM   6430 C CB  . ILE A 1 879  ? 179.113 146.293 190.868 1.00 77.96  ? 897  ILE A CB  1 
ATOM   6431 C CG1 . ILE A 1 879  ? 179.668 147.478 191.662 1.00 82.01  ? 897  ILE A CG1 1 
ATOM   6432 C CG2 . ILE A 1 879  ? 180.253 145.457 190.288 1.00 88.58  ? 897  ILE A CG2 1 
ATOM   6433 C CD1 . ILE A 1 879  ? 180.037 147.126 193.077 1.00 94.25  ? 897  ILE A CD1 1 
ATOM   6434 N N   . THR A 1 880  ? 178.241 149.127 189.183 1.00 82.41  ? 898  THR A N   1 
ATOM   6435 C CA  . THR A 1 880  ? 178.668 150.321 188.477 1.00 81.06  ? 898  THR A CA  1 
ATOM   6436 C C   . THR A 1 880  ? 179.179 151.347 189.475 1.00 80.87  ? 898  THR A C   1 
ATOM   6437 O O   . THR A 1 880  ? 178.741 151.388 190.626 1.00 90.99  ? 898  THR A O   1 
ATOM   6438 C CB  . THR A 1 880  ? 177.528 150.938 187.656 1.00 91.01  ? 898  THR A CB  1 
ATOM   6439 O OG1 . THR A 1 880  ? 176.790 151.853 188.474 1.00 92.11  ? 898  THR A OG1 1 
ATOM   6440 C CG2 . THR A 1 880  ? 176.589 149.862 187.124 1.00 97.45  ? 898  THR A CG2 1 
ATOM   6441 N N   . ALA A 1 881  ? 180.118 152.165 189.018 1.00 76.67  ? 899  ALA A N   1 
ATOM   6442 C CA  . ALA A 1 881  ? 180.675 153.261 189.795 1.00 73.45  ? 899  ALA A CA  1 
ATOM   6443 C C   . ALA A 1 881  ? 180.688 154.504 188.924 1.00 73.96  ? 899  ALA A C   1 
ATOM   6444 O O   . ALA A 1 881  ? 181.039 154.430 187.740 1.00 84.61  ? 899  ALA A O   1 
ATOM   6445 C CB  . ALA A 1 881  ? 182.089 152.939 190.282 1.00 74.16  ? 899  ALA A CB  1 
ATOM   6446 N N   . ILE A 1 882  ? 180.289 155.636 189.506 1.00 68.57  ? 900  ILE A N   1 
ATOM   6447 C CA  . ILE A 1 882  ? 180.280 156.914 188.810 1.00 69.10  ? 900  ILE A CA  1 
ATOM   6448 C C   . ILE A 1 882  ? 180.772 157.994 189.762 1.00 76.91  ? 900  ILE A C   1 
ATOM   6449 O O   . ILE A 1 882  ? 180.677 157.872 190.986 1.00 87.56  ? 900  ILE A O   1 
ATOM   6450 C CB  . ILE A 1 882  ? 178.875 157.251 188.248 1.00 70.88  ? 900  ILE A CB  1 
ATOM   6451 C CG1 . ILE A 1 882  ? 178.972 158.249 187.092 1.00 82.66  ? 900  ILE A CG1 1 
ATOM   6452 C CG2 . ILE A 1 882  ? 177.948 157.761 189.340 1.00 81.47  ? 900  ILE A CG2 1 
ATOM   6453 C CD1 . ILE A 1 882  ? 177.679 158.405 186.322 1.00 90.89  ? 900  ILE A CD1 1 
ATOM   6454 N N   . GLY A 1 883  ? 181.323 159.054 189.179 1.00 79.56  ? 901  GLY A N   1 
ATOM   6455 C CA  . GLY A 1 883  ? 181.891 160.144 189.949 1.00 87.21  ? 901  GLY A CA  1 
ATOM   6456 C C   . GLY A 1 883  ? 180.949 161.310 190.162 1.00 103.00 ? 901  GLY A C   1 
ATOM   6457 O O   . GLY A 1 883  ? 181.240 162.198 190.967 1.00 111.76 ? 901  GLY A O   1 
ATOM   6458 N N   . ASP A 1 884  ? 179.827 161.335 189.447 1.00 108.61 ? 902  ASP A N   1 
ATOM   6459 C CA  . ASP A 1 884  ? 178.866 162.421 189.576 1.00 121.55 ? 902  ASP A CA  1 
ATOM   6460 C C   . ASP A 1 884  ? 177.556 161.980 188.944 1.00 120.93 ? 902  ASP A C   1 
ATOM   6461 O O   . ASP A 1 884  ? 177.524 161.076 188.106 1.00 125.97 ? 902  ASP A O   1 
ATOM   6462 C CB  . ASP A 1 884  ? 179.382 163.707 188.918 1.00 130.34 ? 902  ASP A CB  1 
ATOM   6463 C CG  . ASP A 1 884  ? 178.582 164.933 189.314 1.00 145.17 ? 902  ASP A CG  1 
ATOM   6464 O OD1 . ASP A 1 884  ? 177.570 164.785 190.030 1.00 146.53 ? 902  ASP A OD1 1 
ATOM   6465 O OD2 . ASP A 1 884  ? 178.969 166.050 188.909 1.00 152.39 ? 902  ASP A OD2 1 
ATOM   6466 N N   . VAL A 1 885  ? 176.473 162.631 189.361 1.00 121.96 ? 903  VAL A N   1 
ATOM   6467 C CA  . VAL A 1 885  ? 175.149 162.361 188.813 1.00 124.42 ? 903  VAL A CA  1 
ATOM   6468 C C   . VAL A 1 885  ? 174.975 163.172 187.537 1.00 136.58 ? 903  VAL A C   1 
ATOM   6469 O O   . VAL A 1 885  ? 175.728 164.120 187.286 1.00 142.73 ? 903  VAL A O   1 
ATOM   6470 C CB  . VAL A 1 885  ? 174.050 162.676 189.842 1.00 121.07 ? 903  VAL A CB  1 
ATOM   6471 C CG1 . VAL A 1 885  ? 174.392 162.030 191.170 1.00 120.89 ? 903  VAL A CG1 1 
ATOM   6472 C CG2 . VAL A 1 885  ? 173.871 164.180 190.007 1.00 130.96 ? 903  VAL A CG2 1 
ATOM   6473 N N   . LEU A 1 886  ? 173.979 162.817 186.729 1.00 139.93 ? 904  LEU A N   1 
ATOM   6474 C CA  . LEU A 1 886  ? 173.792 163.438 185.422 1.00 148.59 ? 904  LEU A CA  1 
ATOM   6475 C C   . LEU A 1 886  ? 172.968 164.708 185.591 1.00 159.28 ? 904  LEU A C   1 
ATOM   6476 O O   . LEU A 1 886  ? 171.760 164.645 185.843 1.00 165.06 ? 904  LEU A O   1 
ATOM   6477 C CB  . LEU A 1 886  ? 173.111 162.478 184.449 1.00 146.75 ? 904  LEU A CB  1 
ATOM   6478 C CG  . LEU A 1 886  ? 173.512 160.998 184.447 1.00 142.69 ? 904  LEU A CG  1 
ATOM   6479 C CD1 . LEU A 1 886  ? 172.597 160.130 185.321 1.00 145.95 ? 904  LEU A CD1 1 
ATOM   6480 C CD2 . LEU A 1 886  ? 173.529 160.480 183.019 1.00 128.11 ? 904  LEU A CD2 1 
ATOM   6481 N N   . GLY A 1 887  ? 173.620 165.863 185.460 1.00 168.04 ? 905  GLY A N   1 
ATOM   6482 C CA  . GLY A 1 887  ? 172.926 167.126 185.499 1.00 179.46 ? 905  GLY A CA  1 
ATOM   6483 C C   . GLY A 1 887  ? 172.350 167.491 184.147 1.00 190.41 ? 905  GLY A C   1 
ATOM   6484 O O   . GLY A 1 887  ? 172.555 166.803 183.138 1.00 192.25 ? 905  GLY A O   1 
ATOM   6485 N N   . PRO A 1 888  ? 171.605 168.596 184.105 1.00 190.54 ? 906  PRO A N   1 
ATOM   6486 C CA  . PRO A 1 888  ? 171.110 169.083 182.813 1.00 197.68 ? 906  PRO A CA  1 
ATOM   6487 C C   . PRO A 1 888  ? 172.239 169.630 181.954 1.00 201.81 ? 906  PRO A C   1 
ATOM   6488 O O   . PRO A 1 888  ? 173.282 170.066 182.445 1.00 202.20 ? 906  PRO A O   1 
ATOM   6489 C CB  . PRO A 1 888  ? 170.116 170.189 183.191 1.00 197.75 ? 906  PRO A CB  1 
ATOM   6490 C CG  . PRO A 1 888  ? 169.919 170.079 184.662 1.00 187.78 ? 906  PRO A CG  1 
ATOM   6491 C CD  . PRO A 1 888  ? 171.155 169.463 185.208 1.00 185.60 ? 906  PRO A CD  1 
ATOM   6492 N N   . SER A 1 889  ? 172.012 169.599 180.644 1.00 203.63 ? 907  SER A N   1 
ATOM   6493 C CA  . SER A 1 889  ? 172.968 170.173 179.710 1.00 208.66 ? 907  SER A CA  1 
ATOM   6494 C C   . SER A 1 889  ? 173.043 171.684 179.897 1.00 216.23 ? 907  SER A C   1 
ATOM   6495 O O   . SER A 1 889  ? 172.060 172.339 180.254 1.00 217.63 ? 907  SER A O   1 
ATOM   6496 C CB  . SER A 1 889  ? 172.576 169.842 178.271 1.00 211.91 ? 907  SER A CB  1 
ATOM   6497 O OG  . SER A 1 889  ? 173.605 170.207 177.368 1.00 215.52 ? 907  SER A OG  1 
ATOM   6498 N N   . ILE A 1 890  ? 174.233 172.237 179.654 1.00 219.10 ? 908  ILE A N   1 
ATOM   6499 C CA  . ILE A 1 890  ? 174.444 173.665 179.878 1.00 222.02 ? 908  ILE A CA  1 
ATOM   6500 C C   . ILE A 1 890  ? 173.610 174.484 178.901 1.00 226.90 ? 908  ILE A C   1 
ATOM   6501 O O   . ILE A 1 890  ? 172.997 175.489 179.281 1.00 227.73 ? 908  ILE A O   1 
ATOM   6502 C CB  . ILE A 1 890  ? 175.944 174.020 179.783 1.00 219.60 ? 908  ILE A CB  1 
ATOM   6503 C CG1 . ILE A 1 890  ? 176.800 173.085 180.655 1.00 217.11 ? 908  ILE A CG1 1 
ATOM   6504 C CG2 . ILE A 1 890  ? 176.187 175.483 180.189 1.00 218.69 ? 908  ILE A CG2 1 
ATOM   6505 C CD1 . ILE A 1 890  ? 177.640 172.106 179.861 1.00 220.40 ? 908  ILE A CD1 1 
ATOM   6506 N N   . ASN A 1 891  ? 173.580 174.078 177.630 1.00 230.08 ? 909  ASN A N   1 
ATOM   6507 C CA  . ASN A 1 891  ? 172.798 174.814 176.638 1.00 232.68 ? 909  ASN A CA  1 
ATOM   6508 C C   . ASN A 1 891  ? 171.306 174.763 176.943 1.00 231.71 ? 909  ASN A C   1 
ATOM   6509 O O   . ASN A 1 891  ? 170.600 175.757 176.735 1.00 232.53 ? 909  ASN A O   1 
ATOM   6510 C CB  . ASN A 1 891  ? 173.063 174.277 175.226 1.00 233.86 ? 909  ASN A CB  1 
ATOM   6511 C CG  . ASN A 1 891  ? 172.910 172.764 175.120 1.00 230.09 ? 909  ASN A CG  1 
ATOM   6512 O OD1 . ASN A 1 891  ? 171.975 172.178 175.665 1.00 229.69 ? 909  ASN A OD1 1 
ATOM   6513 N ND2 . ASN A 1 891  ? 173.838 172.128 174.414 1.00 225.38 ? 909  ASN A ND2 1 
ATOM   6514 N N   . GLY A 1 892  ? 170.809 173.620 177.421 1.00 228.27 ? 910  GLY A N   1 
ATOM   6515 C CA  . GLY A 1 892  ? 169.393 173.514 177.733 1.00 226.28 ? 910  GLY A CA  1 
ATOM   6516 C C   . GLY A 1 892  ? 168.964 174.470 178.829 1.00 227.20 ? 910  GLY A C   1 
ATOM   6517 O O   . GLY A 1 892  ? 167.901 175.091 178.742 1.00 230.29 ? 910  GLY A O   1 
ATOM   6518 N N   . LEU A 1 893  ? 169.784 174.605 179.873 1.00 224.23 ? 911  LEU A N   1 
ATOM   6519 C CA  . LEU A 1 893  ? 169.485 175.578 180.917 1.00 223.93 ? 911  LEU A CA  1 
ATOM   6520 C C   . LEU A 1 893  ? 169.700 177.003 180.428 1.00 229.23 ? 911  LEU A C   1 
ATOM   6521 O O   . LEU A 1 893  ? 168.957 177.910 180.822 1.00 230.82 ? 911  LEU A O   1 
ATOM   6522 C CB  . LEU A 1 893  ? 170.345 175.307 182.151 1.00 215.92 ? 911  LEU A CB  1 
ATOM   6523 C CG  . LEU A 1 893  ? 170.294 173.893 182.733 1.00 209.80 ? 911  LEU A CG  1 
ATOM   6524 C CD1 . LEU A 1 893  ? 171.299 173.760 183.865 1.00 198.64 ? 911  LEU A CD1 1 
ATOM   6525 C CD2 . LEU A 1 893  ? 168.890 173.558 183.213 1.00 211.30 ? 911  LEU A CD2 1 
ATOM   6526 N N   . ALA A 1 894  ? 170.705 177.222 179.577 1.00 230.69 ? 912  ALA A N   1 
ATOM   6527 C CA  . ALA A 1 894  ? 170.933 178.546 179.013 1.00 230.36 ? 912  ALA A CA  1 
ATOM   6528 C C   . ALA A 1 894  ? 169.760 179.016 178.168 1.00 233.93 ? 912  ALA A C   1 
ATOM   6529 O O   . ALA A 1 894  ? 169.502 180.223 178.103 1.00 235.90 ? 912  ALA A O   1 
ATOM   6530 C CB  . ALA A 1 894  ? 172.209 178.546 178.171 1.00 228.34 ? 912  ALA A CB  1 
ATOM   6531 N N   . SER A 1 895  ? 169.047 178.091 177.521 1.00 235.49 ? 913  SER A N   1 
ATOM   6532 C CA  . SER A 1 895  ? 167.870 178.472 176.750 1.00 238.09 ? 913  SER A CA  1 
ATOM   6533 C C   . SER A 1 895  ? 166.783 179.059 177.640 1.00 240.36 ? 913  SER A C   1 
ATOM   6534 O O   . SER A 1 895  ? 166.048 179.955 177.209 1.00 243.97 ? 913  SER A O   1 
ATOM   6535 C CB  . SER A 1 895  ? 167.330 177.262 175.988 1.00 237.20 ? 913  SER A CB  1 
ATOM   6536 O OG  . SER A 1 895  ? 166.669 176.365 176.864 1.00 238.00 ? 913  SER A OG  1 
ATOM   6537 N N   . LEU A 1 896  ? 166.666 178.576 178.878 1.00 237.81 ? 914  LEU A N   1 
ATOM   6538 C CA  . LEU A 1 896  ? 165.662 179.092 179.801 1.00 237.28 ? 914  LEU A CA  1 
ATOM   6539 C C   . LEU A 1 896  ? 165.983 180.491 180.316 1.00 239.81 ? 914  LEU A C   1 
ATOM   6540 O O   . LEU A 1 896  ? 165.109 181.121 180.921 1.00 242.24 ? 914  LEU A O   1 
ATOM   6541 C CB  . LEU A 1 896  ? 165.499 178.140 180.994 1.00 230.53 ? 914  LEU A CB  1 
ATOM   6542 C CG  . LEU A 1 896  ? 164.437 177.035 180.908 1.00 226.08 ? 914  LEU A CG  1 
ATOM   6543 C CD1 . LEU A 1 896  ? 163.025 177.592 180.734 1.00 222.38 ? 914  LEU A CD1 1 
ATOM   6544 C CD2 . LEU A 1 896  ? 164.769 176.070 179.778 1.00 227.66 ? 914  LEU A CD2 1 
ATOM   6545 N N   . ILE A 1 897  ? 167.198 180.993 180.095 1.00 238.51 ? 915  ILE A N   1 
ATOM   6546 C CA  . ILE A 1 897  ? 167.539 182.346 180.521 1.00 239.16 ? 915  ILE A CA  1 
ATOM   6547 C C   . ILE A 1 897  ? 166.889 183.331 179.558 1.00 244.56 ? 915  ILE A C   1 
ATOM   6548 O O   . ILE A 1 897  ? 167.015 183.202 178.333 1.00 246.13 ? 915  ILE A O   1 
ATOM   6549 C CB  . ILE A 1 897  ? 169.066 182.535 180.592 1.00 235.69 ? 915  ILE A CB  1 
ATOM   6550 C CG1 . ILE A 1 897  ? 169.741 181.386 181.368 1.00 231.80 ? 915  ILE A CG1 1 
ATOM   6551 C CG2 . ILE A 1 897  ? 169.431 183.871 181.273 1.00 236.76 ? 915  ILE A CG2 1 
ATOM   6552 C CD1 . ILE A 1 897  ? 171.251 181.508 181.479 1.00 231.44 ? 915  ILE A CD1 1 
ATOM   6553 N N   . ARG A 1 898  ? 166.187 184.320 180.109 1.00 246.63 ? 916  ARG A N   1 
ATOM   6554 C CA  . ARG A 1 898  ? 165.398 185.239 179.300 1.00 246.55 ? 916  ARG A CA  1 
ATOM   6555 C C   . ARG A 1 898  ? 165.172 186.530 180.073 1.00 246.85 ? 916  ARG A C   1 
ATOM   6556 O O   . ARG A 1 898  ? 165.327 186.584 181.295 1.00 245.01 ? 916  ARG A O   1 
ATOM   6557 C CB  . ARG A 1 898  ? 164.047 184.627 178.883 1.00 246.90 ? 916  ARG A CB  1 
ATOM   6558 C CG  . ARG A 1 898  ? 163.239 183.909 179.996 1.00 244.62 ? 916  ARG A CG  1 
ATOM   6559 C CD  . ARG A 1 898  ? 162.334 182.792 179.463 1.00 243.54 ? 916  ARG A CD  1 
ATOM   6560 N NE  . ARG A 1 898  ? 163.054 181.754 178.730 1.00 244.28 ? 916  ARG A NE  1 
ATOM   6561 C CZ  . ARG A 1 898  ? 162.489 180.836 177.954 1.00 243.82 ? 916  ARG A CZ  1 
ATOM   6562 N NH1 . ARG A 1 898  ? 161.174 180.759 177.805 1.00 244.84 ? 916  ARG A NH1 1 
ATOM   6563 N NH2 . ARG A 1 898  ? 163.263 179.966 177.312 1.00 242.06 ? 916  ARG A NH2 1 
ATOM   6564 N N   . MET A 1 899  ? 164.805 187.572 179.335 1.00 248.69 ? 917  MET A N   1 
ATOM   6565 C CA  . MET A 1 899  ? 164.537 188.877 179.930 1.00 250.80 ? 917  MET A CA  1 
ATOM   6566 C C   . MET A 1 899  ? 163.193 188.810 180.654 1.00 251.28 ? 917  MET A C   1 
ATOM   6567 O O   . MET A 1 899  ? 162.174 188.548 180.006 1.00 250.19 ? 917  MET A O   1 
ATOM   6568 C CB  . MET A 1 899  ? 164.512 189.948 178.831 1.00 252.82 ? 917  MET A CB  1 
ATOM   6569 C CG  . MET A 1 899  ? 163.756 191.278 179.086 1.00 256.00 ? 917  MET A CG  1 
ATOM   6570 S SD  . MET A 1 899  ? 163.706 192.058 180.721 1.00 258.78 ? 917  MET A SD  1 
ATOM   6571 C CE  . MET A 1 899  ? 165.416 192.008 181.248 1.00 254.83 ? 917  MET A CE  1 
ATOM   6572 N N   . PRO A 1 900  ? 163.129 189.040 181.971 1.00 251.60 ? 918  PRO A N   1 
ATOM   6573 C CA  . PRO A 1 900  ? 161.813 189.004 182.633 1.00 251.94 ? 918  PRO A CA  1 
ATOM   6574 C C   . PRO A 1 900  ? 160.992 190.245 182.311 1.00 254.08 ? 918  PRO A C   1 
ATOM   6575 O O   . PRO A 1 900  ? 161.400 191.368 182.613 1.00 254.90 ? 918  PRO A O   1 
ATOM   6576 C CB  . PRO A 1 900  ? 162.164 188.934 184.127 1.00 249.77 ? 918  PRO A CB  1 
ATOM   6577 C CG  . PRO A 1 900  ? 163.590 188.561 184.187 1.00 246.69 ? 918  PRO A CG  1 
ATOM   6578 C CD  . PRO A 1 900  ? 164.205 189.159 182.974 1.00 249.21 ? 918  PRO A CD  1 
ATOM   6579 N N   . TYR A 1 901  ? 159.816 190.030 181.716 1.00 253.34 ? 919  TYR A N   1 
ATOM   6580 C CA  . TYR A 1 901  ? 158.931 191.111 181.295 1.00 253.66 ? 919  TYR A CA  1 
ATOM   6581 C C   . TYR A 1 901  ? 157.503 190.837 181.751 1.00 254.38 ? 919  TYR A C   1 
ATOM   6582 O O   . TYR A 1 901  ? 157.255 189.885 182.499 1.00 254.57 ? 919  TYR A O   1 
ATOM   6583 C CB  . TYR A 1 901  ? 158.986 191.278 179.774 1.00 254.48 ? 919  TYR A CB  1 
ATOM   6584 C CG  . TYR A 1 901  ? 158.410 190.111 179.000 1.00 254.99 ? 919  TYR A CG  1 
ATOM   6585 C CD1 . TYR A 1 901  ? 159.166 188.972 178.758 1.00 253.47 ? 919  TYR A CD1 1 
ATOM   6586 C CD2 . TYR A 1 901  ? 157.114 190.153 178.504 1.00 255.85 ? 919  TYR A CD2 1 
ATOM   6587 C CE1 . TYR A 1 901  ? 158.645 187.906 178.051 1.00 253.28 ? 919  TYR A CE1 1 
ATOM   6588 C CE2 . TYR A 1 901  ? 156.585 189.092 177.796 1.00 256.17 ? 919  TYR A CE2 1 
ATOM   6589 C CZ  . TYR A 1 901  ? 157.355 187.971 177.572 1.00 254.86 ? 919  TYR A CZ  1 
ATOM   6590 O OH  . TYR A 1 901  ? 156.833 186.912 176.867 1.00 251.82 ? 919  TYR A OH  1 
ATOM   6591 N N   . GLY A 1 902  ? 156.561 191.664 181.306 1.00 255.47 ? 920  GLY A N   1 
ATOM   6592 C CA  . GLY A 1 902  ? 155.166 191.488 181.656 1.00 256.83 ? 920  GLY A CA  1 
ATOM   6593 C C   . GLY A 1 902  ? 154.834 192.001 183.041 1.00 257.58 ? 920  GLY A C   1 
ATOM   6594 O O   . GLY A 1 902  ? 155.503 192.903 183.554 1.00 254.16 ? 920  GLY A O   1 
ATOM   6595 N N   . CYS A 1 903  ? 153.804 191.430 183.658 1.00 260.01 ? 921  CYS A N   1 
ATOM   6596 C CA  . CYS A 1 903  ? 153.378 191.847 184.986 1.00 256.50 ? 921  CYS A CA  1 
ATOM   6597 C C   . CYS A 1 903  ? 154.332 191.264 186.027 1.00 255.92 ? 921  CYS A C   1 
ATOM   6598 O O   . CYS A 1 903  ? 155.379 190.697 185.701 1.00 256.92 ? 921  CYS A O   1 
ATOM   6599 C CB  . CYS A 1 903  ? 151.935 191.420 185.237 1.00 252.23 ? 921  CYS A CB  1 
ATOM   6600 S SG  . CYS A 1 903  ? 151.752 189.694 185.740 1.00 252.95 ? 921  CYS A SG  1 
ATOM   6601 N N   . GLY A 1 904  ? 153.978 191.409 187.305 1.00 252.70 ? 922  GLY A N   1 
ATOM   6602 C CA  . GLY A 1 904  ? 154.813 190.856 188.358 1.00 251.78 ? 922  GLY A CA  1 
ATOM   6603 C C   . GLY A 1 904  ? 154.897 189.343 188.301 1.00 255.94 ? 922  GLY A C   1 
ATOM   6604 O O   . GLY A 1 904  ? 155.968 188.764 188.501 1.00 257.22 ? 922  GLY A O   1 
ATOM   6605 N N   . GLU A 1 905  ? 153.772 188.680 188.026 1.00 256.92 ? 923  GLU A N   1 
ATOM   6606 C CA  . GLU A 1 905  ? 153.779 187.223 187.954 1.00 258.79 ? 923  GLU A CA  1 
ATOM   6607 C C   . GLU A 1 905  ? 154.561 186.731 186.742 1.00 259.30 ? 923  GLU A C   1 
ATOM   6608 O O   . GLU A 1 905  ? 155.335 185.774 186.847 1.00 259.29 ? 923  GLU A O   1 
ATOM   6609 C CB  . GLU A 1 905  ? 152.349 186.691 187.921 1.00 256.73 ? 923  GLU A CB  1 
ATOM   6610 C CG  . GLU A 1 905  ? 151.551 187.003 189.171 1.00 257.19 ? 923  GLU A CG  1 
ATOM   6611 C CD  . GLU A 1 905  ? 150.159 186.411 189.131 1.00 261.03 ? 923  GLU A CD  1 
ATOM   6612 O OE1 . GLU A 1 905  ? 149.830 185.733 188.135 1.00 261.30 ? 923  GLU A OE1 1 
ATOM   6613 O OE2 . GLU A 1 905  ? 149.391 186.629 190.091 1.00 263.41 ? 923  GLU A OE2 1 
ATOM   6614 N N   . GLN A 1 906  ? 154.369 187.367 185.583 1.00 260.51 ? 924  GLN A N   1 
ATOM   6615 C CA  . GLN A 1 906  ? 155.159 187.010 184.408 1.00 261.09 ? 924  GLN A CA  1 
ATOM   6616 C C   . GLN A 1 906  ? 156.636 187.302 184.639 1.00 260.73 ? 924  GLN A C   1 
ATOM   6617 O O   . GLN A 1 906  ? 157.506 186.524 184.220 1.00 260.20 ? 924  GLN A O   1 
ATOM   6618 C CB  . GLN A 1 906  ? 154.654 187.772 183.182 1.00 260.32 ? 924  GLN A CB  1 
ATOM   6619 C CG  . GLN A 1 906  ? 153.236 187.422 182.760 1.00 259.37 ? 924  GLN A CG  1 
ATOM   6620 C CD  . GLN A 1 906  ? 152.660 188.430 181.783 1.00 257.81 ? 924  GLN A CD  1 
ATOM   6621 O OE1 . GLN A 1 906  ? 152.515 189.609 182.107 1.00 260.65 ? 924  GLN A OE1 1 
ATOM   6622 N NE2 . GLN A 1 906  ? 152.331 187.972 180.580 1.00 251.70 ? 924  GLN A NE2 1 
ATOM   6623 N N   . ASN A 1 907  ? 156.928 188.425 185.300 1.00 260.21 ? 925  ASN A N   1 
ATOM   6624 C CA  . ASN A 1 907  ? 158.301 188.751 185.665 1.00 259.32 ? 925  ASN A CA  1 
ATOM   6625 C C   . ASN A 1 907  ? 158.921 187.648 186.511 1.00 257.50 ? 925  ASN A C   1 
ATOM   6626 O O   . ASN A 1 907  ? 160.020 187.174 186.209 1.00 254.84 ? 925  ASN A O   1 
ATOM   6627 C CB  . ASN A 1 907  ? 158.332 190.083 186.416 1.00 257.70 ? 925  ASN A CB  1 
ATOM   6628 C CG  . ASN A 1 907  ? 159.715 190.439 186.917 1.00 254.02 ? 925  ASN A CG  1 
ATOM   6629 O OD1 . ASN A 1 907  ? 160.539 190.972 186.176 1.00 253.00 ? 925  ASN A OD1 1 
ATOM   6630 N ND2 . ASN A 1 907  ? 159.977 190.146 188.186 1.00 251.90 ? 925  ASN A ND2 1 
ATOM   6631 N N   . MET A 1 908  ? 158.216 187.205 187.554 1.00 256.81 ? 926  MET A N   1 
ATOM   6632 C CA  . MET A 1 908  ? 158.738 186.144 188.411 1.00 250.34 ? 926  MET A CA  1 
ATOM   6633 C C   . MET A 1 908  ? 158.885 184.835 187.647 1.00 249.59 ? 926  MET A C   1 
ATOM   6634 O O   . MET A 1 908  ? 159.860 184.100 187.848 1.00 245.92 ? 926  MET A O   1 
ATOM   6635 C CB  . MET A 1 908  ? 157.821 185.953 189.620 1.00 249.03 ? 926  MET A CB  1 
ATOM   6636 C CG  . MET A 1 908  ? 158.496 185.363 190.863 1.00 243.86 ? 926  MET A CG  1 
ATOM   6637 S SD  . MET A 1 908  ? 159.900 186.265 191.571 1.00 247.15 ? 926  MET A SD  1 
ATOM   6638 C CE  . MET A 1 908  ? 159.486 187.976 191.244 1.00 247.34 ? 926  MET A CE  1 
ATOM   6639 N N   . ILE A 1 909  ? 157.925 184.530 186.768 1.00 252.97 ? 927  ILE A N   1 
ATOM   6640 C CA  . ILE A 1 909  ? 157.965 183.290 185.997 1.00 251.09 ? 927  ILE A CA  1 
ATOM   6641 C C   . ILE A 1 909  ? 159.212 183.257 185.124 1.00 247.97 ? 927  ILE A C   1 
ATOM   6642 O O   . ILE A 1 909  ? 159.908 182.237 185.048 1.00 244.33 ? 927  ILE A O   1 
ATOM   6643 C CB  . ILE A 1 909  ? 156.670 183.150 185.168 1.00 252.56 ? 927  ILE A CB  1 
ATOM   6644 C CG1 . ILE A 1 909  ? 155.548 182.593 186.050 1.00 249.05 ? 927  ILE A CG1 1 
ATOM   6645 C CG2 . ILE A 1 909  ? 156.866 182.239 183.933 1.00 250.87 ? 927  ILE A CG2 1 
ATOM   6646 C CD1 . ILE A 1 909  ? 154.145 182.806 185.496 1.00 249.17 ? 927  ILE A CD1 1 
ATOM   6647 N N   . ASN A 1 910  ? 159.515 184.366 184.458 1.00 249.92 ? 928  ASN A N   1 
ATOM   6648 C CA  . ASN A 1 910  ? 160.687 184.449 183.597 1.00 248.13 ? 928  ASN A CA  1 
ATOM   6649 C C   . ASN A 1 910  ? 161.981 184.736 184.357 1.00 245.92 ? 928  ASN A C   1 
ATOM   6650 O O   . ASN A 1 910  ? 163.058 184.650 183.758 1.00 246.25 ? 928  ASN A O   1 
ATOM   6651 C CB  . ASN A 1 910  ? 160.465 185.528 182.536 1.00 249.44 ? 928  ASN A CB  1 
ATOM   6652 C CG  . ASN A 1 910  ? 159.354 185.175 181.564 1.00 249.52 ? 928  ASN A CG  1 
ATOM   6653 O OD1 . ASN A 1 910  ? 158.371 185.905 181.439 1.00 251.54 ? 928  ASN A OD1 1 
ATOM   6654 N ND2 . ASN A 1 910  ? 159.509 184.057 180.864 1.00 247.99 ? 928  ASN A ND2 1 
ATOM   6655 N N   . PHE A 1 911  ? 161.907 185.068 185.649 1.00 242.72 ? 929  PHE A N   1 
ATOM   6656 C CA  . PHE A 1 911  ? 163.077 185.399 186.457 1.00 235.57 ? 929  PHE A CA  1 
ATOM   6657 C C   . PHE A 1 911  ? 163.597 184.229 187.284 1.00 229.77 ? 929  PHE A C   1 
ATOM   6658 O O   . PHE A 1 911  ? 164.804 183.971 187.288 1.00 223.32 ? 929  PHE A O   1 
ATOM   6659 C CB  . PHE A 1 911  ? 162.736 186.570 187.386 1.00 234.20 ? 929  PHE A CB  1 
ATOM   6660 C CG  . PHE A 1 911  ? 163.580 186.633 188.620 1.00 229.20 ? 929  PHE A CG  1 
ATOM   6661 C CD1 . PHE A 1 911  ? 164.916 186.987 188.562 1.00 229.31 ? 929  PHE A CD1 1 
ATOM   6662 C CD2 . PHE A 1 911  ? 163.021 186.346 189.850 1.00 229.35 ? 929  PHE A CD2 1 
ATOM   6663 C CE1 . PHE A 1 911  ? 165.675 187.039 189.713 1.00 231.33 ? 929  PHE A CE1 1 
ATOM   6664 C CE2 . PHE A 1 911  ? 163.774 186.400 190.995 1.00 228.14 ? 929  PHE A CE2 1 
ATOM   6665 C CZ  . PHE A 1 911  ? 165.103 186.747 190.930 1.00 229.15 ? 929  PHE A CZ  1 
ATOM   6666 N N   . ALA A 1 912  ? 162.714 183.531 188.002 1.00 230.39 ? 930  ALA A N   1 
ATOM   6667 C CA  . ALA A 1 912  ? 163.115 182.523 188.981 1.00 224.22 ? 930  ALA A CA  1 
ATOM   6668 C C   . ALA A 1 912  ? 163.964 181.400 188.380 1.00 219.88 ? 930  ALA A C   1 
ATOM   6669 O O   . ALA A 1 912  ? 164.992 181.034 188.972 1.00 216.17 ? 930  ALA A O   1 
ATOM   6670 C CB  . ALA A 1 912  ? 161.880 181.941 189.674 1.00 223.99 ? 930  ALA A CB  1 
ATOM   6671 N N   . PRO A 1 913  ? 163.588 180.821 187.231 1.00 222.84 ? 931  PRO A N   1 
ATOM   6672 C CA  . PRO A 1 913  ? 164.485 179.834 186.608 1.00 221.06 ? 931  PRO A CA  1 
ATOM   6673 C C   . PRO A 1 913  ? 165.859 180.385 186.285 1.00 218.01 ? 931  PRO A C   1 
ATOM   6674 O O   . PRO A 1 913  ? 166.847 179.655 186.415 1.00 214.60 ? 931  PRO A O   1 
ATOM   6675 C CB  . PRO A 1 913  ? 163.729 179.426 185.336 1.00 223.51 ? 931  PRO A CB  1 
ATOM   6676 C CG  . PRO A 1 913  ? 162.316 179.670 185.653 1.00 227.63 ? 931  PRO A CG  1 
ATOM   6677 C CD  . PRO A 1 913  ? 162.307 180.902 186.502 1.00 229.85 ? 931  PRO A CD  1 
ATOM   6678 N N   . ASN A 1 914  ? 165.959 181.662 185.909 1.00 220.62 ? 932  ASN A N   1 
ATOM   6679 C CA  . ASN A 1 914  ? 167.259 182.230 185.563 1.00 218.81 ? 932  ASN A CA  1 
ATOM   6680 C C   . ASN A 1 914  ? 168.183 182.266 186.775 1.00 210.74 ? 932  ASN A C   1 
ATOM   6681 O O   . ASN A 1 914  ? 169.323 181.789 186.715 1.00 208.32 ? 932  ASN A O   1 
ATOM   6682 C CB  . ASN A 1 914  ? 167.086 183.636 184.983 1.00 225.11 ? 932  ASN A CB  1 
ATOM   6683 C CG  . ASN A 1 914  ? 166.077 183.683 183.851 1.00 236.15 ? 932  ASN A CG  1 
ATOM   6684 O OD1 . ASN A 1 914  ? 165.618 182.648 183.370 1.00 238.26 ? 932  ASN A OD1 1 
ATOM   6685 N ND2 . ASN A 1 914  ? 165.727 184.890 183.421 1.00 242.55 ? 932  ASN A ND2 1 
ATOM   6686 N N   . ILE A 1 915  ? 167.702 182.815 187.893 1.00 208.17 ? 933  ILE A N   1 
ATOM   6687 C CA  . ILE A 1 915  ? 168.539 182.902 189.087 1.00 206.22 ? 933  ILE A CA  1 
ATOM   6688 C C   . ILE A 1 915  ? 168.841 181.515 189.638 1.00 202.46 ? 933  ILE A C   1 
ATOM   6689 O O   . ILE A 1 915  ? 169.955 181.261 190.117 1.00 198.40 ? 933  ILE A O   1 
ATOM   6690 C CB  . ILE A 1 915  ? 167.889 183.813 190.153 1.00 209.22 ? 933  ILE A CB  1 
ATOM   6691 C CG1 . ILE A 1 915  ? 168.826 183.976 191.359 1.00 210.00 ? 933  ILE A CG1 1 
ATOM   6692 C CG2 . ILE A 1 915  ? 166.524 183.273 190.613 1.00 211.62 ? 933  ILE A CG2 1 
ATOM   6693 C CD1 . ILE A 1 915  ? 168.370 185.005 192.360 1.00 214.22 ? 933  ILE A CD1 1 
ATOM   6694 N N   . TYR A 1 916  ? 167.877 180.593 189.592 1.00 204.32 ? 934  TYR A N   1 
ATOM   6695 C CA  . TYR A 1 916  ? 168.142 179.267 190.141 1.00 202.53 ? 934  TYR A CA  1 
ATOM   6696 C C   . TYR A 1 916  ? 169.137 178.501 189.274 1.00 201.01 ? 934  TYR A C   1 
ATOM   6697 O O   . TYR A 1 916  ? 169.996 177.777 189.796 1.00 198.97 ? 934  TYR A O   1 
ATOM   6698 C CB  . TYR A 1 916  ? 166.831 178.502 190.313 1.00 203.17 ? 934  TYR A CB  1 
ATOM   6699 C CG  . TYR A 1 916  ? 166.210 178.749 191.671 1.00 201.08 ? 934  TYR A CG  1 
ATOM   6700 C CD1 . TYR A 1 916  ? 165.367 179.831 191.885 1.00 203.80 ? 934  TYR A CD1 1 
ATOM   6701 C CD2 . TYR A 1 916  ? 166.481 177.913 192.743 1.00 195.90 ? 934  TYR A CD2 1 
ATOM   6702 C CE1 . TYR A 1 916  ? 164.810 180.072 193.124 1.00 204.65 ? 934  TYR A CE1 1 
ATOM   6703 C CE2 . TYR A 1 916  ? 165.923 178.144 193.985 1.00 197.40 ? 934  TYR A CE2 1 
ATOM   6704 C CZ  . TYR A 1 916  ? 165.088 179.222 194.170 1.00 201.24 ? 934  TYR A CZ  1 
ATOM   6705 O OH  . TYR A 1 916  ? 164.532 179.453 195.407 1.00 199.54 ? 934  TYR A OH  1 
ATOM   6706 N N   . ILE A 1 917  ? 169.065 178.672 187.952 1.00 203.74 ? 935  ILE A N   1 
ATOM   6707 C CA  . ILE A 1 917  ? 170.060 178.071 187.073 1.00 200.26 ? 935  ILE A CA  1 
ATOM   6708 C C   . ILE A 1 917  ? 171.422 178.704 187.317 1.00 195.83 ? 935  ILE A C   1 
ATOM   6709 O O   . ILE A 1 917  ? 172.452 178.026 187.253 1.00 191.52 ? 935  ILE A O   1 
ATOM   6710 C CB  . ILE A 1 917  ? 169.610 178.199 185.603 1.00 202.39 ? 935  ILE A CB  1 
ATOM   6711 C CG1 . ILE A 1 917  ? 168.654 177.056 185.257 1.00 202.33 ? 935  ILE A CG1 1 
ATOM   6712 C CG2 . ILE A 1 917  ? 170.799 178.179 184.622 1.00 202.24 ? 935  ILE A CG2 1 
ATOM   6713 C CD1 . ILE A 1 917  ? 167.703 177.367 184.121 1.00 210.26 ? 935  ILE A CD1 1 
ATOM   6714 N N   . LEU A 1 918  ? 171.454 180.013 187.582 1.00 197.01 ? 936  LEU A N   1 
ATOM   6715 C CA  . LEU A 1 918  ? 172.719 180.664 187.906 1.00 197.10 ? 936  LEU A CA  1 
ATOM   6716 C C   . LEU A 1 918  ? 173.327 180.067 189.168 1.00 194.85 ? 936  LEU A C   1 
ATOM   6717 O O   . LEU A 1 918  ? 174.532 179.801 189.218 1.00 195.01 ? 936  LEU A O   1 
ATOM   6718 C CB  . LEU A 1 918  ? 172.504 182.172 188.065 1.00 199.93 ? 936  LEU A CB  1 
ATOM   6719 C CG  . LEU A 1 918  ? 173.648 183.035 188.615 1.00 201.69 ? 936  LEU A CG  1 
ATOM   6720 C CD1 . LEU A 1 918  ? 174.870 182.958 187.716 1.00 205.51 ? 936  LEU A CD1 1 
ATOM   6721 C CD2 . LEU A 1 918  ? 173.187 184.475 188.761 1.00 204.54 ? 936  LEU A CD2 1 
ATOM   6722 N N   . ASP A 1 919  ? 172.503 179.841 190.192 1.00 193.27 ? 937  ASP A N   1 
ATOM   6723 C CA  . ASP A 1 919  ? 173.009 179.253 191.430 1.00 192.04 ? 937  ASP A CA  1 
ATOM   6724 C C   . ASP A 1 919  ? 173.515 177.833 191.204 1.00 188.01 ? 937  ASP A C   1 
ATOM   6725 O O   . ASP A 1 919  ? 174.580 177.457 191.714 1.00 186.32 ? 937  ASP A O   1 
ATOM   6726 C CB  . ASP A 1 919  ? 171.919 179.267 192.500 1.00 199.13 ? 937  ASP A CB  1 
ATOM   6727 C CG  . ASP A 1 919  ? 172.483 179.352 193.902 1.00 198.82 ? 937  ASP A CG  1 
ATOM   6728 O OD1 . ASP A 1 919  ? 173.366 178.537 194.239 1.00 193.04 ? 937  ASP A OD1 1 
ATOM   6729 O OD2 . ASP A 1 919  ? 172.046 180.236 194.669 1.00 206.85 ? 937  ASP A OD2 1 
ATOM   6730 N N   . TYR A 1 920  ? 172.766 177.031 190.443 1.00 189.14 ? 938  TYR A N   1 
ATOM   6731 C CA  . TYR A 1 920  ? 173.196 175.664 190.160 1.00 185.62 ? 938  TYR A CA  1 
ATOM   6732 C C   . TYR A 1 920  ? 174.500 175.643 189.374 1.00 183.78 ? 938  TYR A C   1 
ATOM   6733 O O   . TYR A 1 920  ? 175.400 174.850 189.673 1.00 181.82 ? 938  TYR A O   1 
ATOM   6734 C CB  . TYR A 1 920  ? 172.100 174.926 189.395 1.00 183.29 ? 938  TYR A CB  1 
ATOM   6735 C CG  . TYR A 1 920  ? 172.549 173.626 188.772 1.00 175.55 ? 938  TYR A CG  1 
ATOM   6736 C CD1 . TYR A 1 920  ? 172.747 172.494 189.546 1.00 170.29 ? 938  TYR A CD1 1 
ATOM   6737 C CD2 . TYR A 1 920  ? 172.746 173.525 187.404 1.00 176.99 ? 938  TYR A CD2 1 
ATOM   6738 C CE1 . TYR A 1 920  ? 173.147 171.304 188.976 1.00 169.82 ? 938  TYR A CE1 1 
ATOM   6739 C CE2 . TYR A 1 920  ? 173.144 172.340 186.826 1.00 174.44 ? 938  TYR A CE2 1 
ATOM   6740 C CZ  . TYR A 1 920  ? 173.339 171.231 187.616 1.00 172.46 ? 938  TYR A CZ  1 
ATOM   6741 O OH  . TYR A 1 920  ? 173.740 170.046 187.047 1.00 176.69 ? 938  TYR A OH  1 
ATOM   6742 N N   . LEU A 1 921  ? 174.622 176.510 188.369 1.00 186.32 ? 939  LEU A N   1 
ATOM   6743 C CA  . LEU A 1 921  ? 175.854 176.582 187.594 1.00 188.66 ? 939  LEU A CA  1 
ATOM   6744 C C   . LEU A 1 921  ? 177.023 177.053 188.449 1.00 190.63 ? 939  LEU A C   1 
ATOM   6745 O O   . LEU A 1 921  ? 178.142 176.552 188.293 1.00 191.90 ? 939  LEU A O   1 
ATOM   6746 C CB  . LEU A 1 921  ? 175.661 177.509 186.391 1.00 191.00 ? 939  LEU A CB  1 
ATOM   6747 C CG  . LEU A 1 921  ? 175.284 176.863 185.053 1.00 189.23 ? 939  LEU A CG  1 
ATOM   6748 C CD1 . LEU A 1 921  ? 176.486 176.177 184.435 1.00 196.42 ? 939  LEU A CD1 1 
ATOM   6749 C CD2 . LEU A 1 921  ? 174.133 175.878 185.204 1.00 187.06 ? 939  LEU A CD2 1 
ATOM   6750 N N   . THR A 1 922  ? 176.788 178.013 189.349 1.00 190.89 ? 940  THR A N   1 
ATOM   6751 C CA  . THR A 1 922  ? 177.851 178.472 190.237 1.00 190.14 ? 940  THR A CA  1 
ATOM   6752 C C   . THR A 1 922  ? 178.326 177.352 191.152 1.00 185.13 ? 940  THR A C   1 
ATOM   6753 O O   . THR A 1 922  ? 179.534 177.163 191.333 1.00 185.39 ? 940  THR A O   1 
ATOM   6754 C CB  . THR A 1 922  ? 177.367 179.660 191.069 1.00 192.67 ? 940  THR A CB  1 
ATOM   6755 O OG1 . THR A 1 922  ? 176.604 180.550 190.245 1.00 196.94 ? 940  THR A OG1 1 
ATOM   6756 C CG2 . THR A 1 922  ? 178.546 180.414 191.671 1.00 189.54 ? 940  THR A CG2 1 
ATOM   6757 N N   . LYS A 1 923  ? 177.395 176.595 191.732 1.00 181.63 ? 941  LYS A N   1 
ATOM   6758 C CA  . LYS A 1 923  ? 177.782 175.498 192.610 1.00 177.34 ? 941  LYS A CA  1 
ATOM   6759 C C   . LYS A 1 923  ? 178.306 174.284 191.853 1.00 178.40 ? 941  LYS A C   1 
ATOM   6760 O O   . LYS A 1 923  ? 178.906 173.404 192.480 1.00 176.73 ? 941  LYS A O   1 
ATOM   6761 C CB  . LYS A 1 923  ? 176.606 175.084 193.498 1.00 173.08 ? 941  LYS A CB  1 
ATOM   6762 C CG  . LYS A 1 923  ? 176.541 175.864 194.804 1.00 171.45 ? 941  LYS A CG  1 
ATOM   6763 C CD  . LYS A 1 923  ? 175.132 175.930 195.364 1.00 173.03 ? 941  LYS A CD  1 
ATOM   6764 C CE  . LYS A 1 923  ? 175.088 176.726 196.657 1.00 169.48 ? 941  LYS A CE  1 
ATOM   6765 N NZ  . LYS A 1 923  ? 173.696 176.928 197.144 1.00 165.43 ? 941  LYS A NZ  1 
ATOM   6766 N N   . LYS A 1 924  ? 178.101 174.215 190.535 1.00 178.81 ? 942  LYS A N   1 
ATOM   6767 C CA  . LYS A 1 924  ? 178.692 173.175 189.700 1.00 178.63 ? 942  LYS A CA  1 
ATOM   6768 C C   . LYS A 1 924  ? 179.996 173.602 189.040 1.00 186.04 ? 942  LYS A C   1 
ATOM   6769 O O   . LYS A 1 924  ? 180.725 172.739 188.542 1.00 189.45 ? 942  LYS A O   1 
ATOM   6770 C CB  . LYS A 1 924  ? 177.703 172.745 188.613 1.00 179.25 ? 942  LYS A CB  1 
ATOM   6771 C CG  . LYS A 1 924  ? 176.780 171.620 189.036 1.00 177.83 ? 942  LYS A CG  1 
ATOM   6772 C CD  . LYS A 1 924  ? 177.451 170.261 188.923 1.00 175.35 ? 942  LYS A CD  1 
ATOM   6773 C CE  . LYS A 1 924  ? 176.472 169.136 189.214 1.00 169.43 ? 942  LYS A CE  1 
ATOM   6774 N NZ  . LYS A 1 924  ? 177.148 167.813 189.302 1.00 161.37 ? 942  LYS A NZ  1 
ATOM   6775 N N   . LYS A 1 925  ? 180.302 174.901 189.017 1.00 189.87 ? 943  LYS A N   1 
ATOM   6776 C CA  . LYS A 1 925  ? 181.548 175.421 188.453 1.00 196.86 ? 943  LYS A CA  1 
ATOM   6777 C C   . LYS A 1 925  ? 181.658 175.086 186.963 1.00 203.05 ? 943  LYS A C   1 
ATOM   6778 O O   . LYS A 1 925  ? 182.573 174.393 186.515 1.00 204.22 ? 943  LYS A O   1 
ATOM   6779 C CB  . LYS A 1 925  ? 182.766 174.898 189.226 1.00 195.77 ? 943  LYS A CB  1 
ATOM   6780 C CG  . LYS A 1 925  ? 182.720 175.145 190.732 1.00 191.22 ? 943  LYS A CG  1 
ATOM   6781 C CD  . LYS A 1 925  ? 183.863 174.440 191.451 1.00 187.82 ? 943  LYS A CD  1 
ATOM   6782 C CE  . LYS A 1 925  ? 183.617 174.346 192.951 1.00 185.24 ? 943  LYS A CE  1 
ATOM   6783 N NZ  . LYS A 1 925  ? 182.956 175.559 193.509 1.00 188.83 ? 943  LYS A NZ  1 
ATOM   6784 N N   . GLN A 1 926  ? 180.688 175.592 186.201 1.00 205.26 ? 944  GLN A N   1 
ATOM   6785 C CA  . GLN A 1 926  ? 180.676 175.488 184.744 1.00 208.83 ? 944  GLN A CA  1 
ATOM   6786 C C   . GLN A 1 926  ? 180.245 176.818 184.139 1.00 215.44 ? 944  GLN A C   1 
ATOM   6787 O O   . GLN A 1 926  ? 179.481 176.867 183.170 1.00 215.17 ? 944  GLN A O   1 
ATOM   6788 C CB  . GLN A 1 926  ? 179.764 174.354 184.265 1.00 206.41 ? 944  GLN A CB  1 
ATOM   6789 C CG  . GLN A 1 926  ? 179.775 173.086 185.119 1.00 206.05 ? 944  GLN A CG  1 
ATOM   6790 C CD  . GLN A 1 926  ? 178.814 172.034 184.604 1.00 205.67 ? 944  GLN A CD  1 
ATOM   6791 O OE1 . GLN A 1 926  ? 178.132 172.239 183.600 1.00 206.55 ? 944  GLN A OE1 1 
ATOM   6792 N NE2 . GLN A 1 926  ? 178.753 170.900 185.291 1.00 202.55 ? 944  GLN A NE2 1 
ATOM   6793 N N   . LEU A 1 927  ? 180.741 177.915 184.706 1.00 222.40 ? 945  LEU A N   1 
ATOM   6794 C CA  . LEU A 1 927  ? 180.307 179.242 184.295 1.00 230.87 ? 945  LEU A CA  1 
ATOM   6795 C C   . LEU A 1 927  ? 180.933 179.636 182.964 1.00 239.03 ? 945  LEU A C   1 
ATOM   6796 O O   . LEU A 1 927  ? 182.056 179.237 182.642 1.00 242.19 ? 945  LEU A O   1 
ATOM   6797 C CB  . LEU A 1 927  ? 180.685 180.287 185.351 1.00 229.38 ? 945  LEU A CB  1 
ATOM   6798 C CG  . LEU A 1 927  ? 180.141 180.213 186.786 1.00 214.96 ? 945  LEU A CG  1 
ATOM   6799 C CD1 . LEU A 1 927  ? 178.632 180.060 186.789 1.00 205.59 ? 945  LEU A CD1 1 
ATOM   6800 C CD2 . LEU A 1 927  ? 180.793 179.104 187.607 1.00 206.96 ? 945  LEU A CD2 1 
ATOM   6801 N N   . THR A 1 928  ? 180.186 180.417 182.188 1.00 243.01 ? 946  THR A N   1 
ATOM   6802 C CA  . THR A 1 928  ? 180.710 181.165 181.055 1.00 249.36 ? 946  THR A CA  1 
ATOM   6803 C C   . THR A 1 928  ? 180.424 182.642 181.293 1.00 255.09 ? 946  THR A C   1 
ATOM   6804 O O   . THR A 1 928  ? 179.323 183.007 181.720 1.00 255.34 ? 946  THR A O   1 
ATOM   6805 C CB  . THR A 1 928  ? 180.086 180.708 179.730 1.00 249.42 ? 946  THR A CB  1 
ATOM   6806 O OG1 . THR A 1 928  ? 178.840 181.376 179.524 1.00 250.97 ? 946  THR A OG1 1 
ATOM   6807 C CG2 . THR A 1 928  ? 179.853 179.199 179.731 1.00 245.14 ? 946  THR A CG2 1 
ATOM   6808 N N   . ASP A 1 929  ? 181.431 183.482 181.034 1.00 260.06 ? 947  ASP A N   1 
ATOM   6809 C CA  . ASP A 1 929  ? 181.342 184.892 181.431 1.00 264.37 ? 947  ASP A CA  1 
ATOM   6810 C C   . ASP A 1 929  ? 180.197 185.602 180.720 1.00 263.12 ? 947  ASP A C   1 
ATOM   6811 O O   . ASP A 1 929  ? 179.500 186.424 181.327 1.00 261.38 ? 947  ASP A O   1 
ATOM   6812 C CB  . ASP A 1 929  ? 182.646 185.663 181.162 1.00 269.75 ? 947  ASP A CB  1 
ATOM   6813 C CG  . ASP A 1 929  ? 183.360 185.236 179.888 1.00 271.83 ? 947  ASP A CG  1 
ATOM   6814 O OD1 . ASP A 1 929  ? 182.678 185.078 178.853 1.00 269.62 ? 947  ASP A OD1 1 
ATOM   6815 O OD2 . ASP A 1 929  ? 184.597 185.068 179.926 1.00 276.47 ? 947  ASP A OD2 1 
ATOM   6816 N N   . ASN A 1 930  ? 179.996 185.312 179.432 1.00 262.78 ? 948  ASN A N   1 
ATOM   6817 C CA  . ASN A 1 930  ? 178.957 186.008 178.677 1.00 260.49 ? 948  ASN A CA  1 
ATOM   6818 C C   . ASN A 1 930  ? 177.567 185.692 179.222 1.00 257.78 ? 948  ASN A C   1 
ATOM   6819 O O   . ASN A 1 930  ? 176.762 186.606 179.447 1.00 255.56 ? 948  ASN A O   1 
ATOM   6820 C CB  . ASN A 1 930  ? 179.049 185.661 177.187 1.00 257.96 ? 948  ASN A CB  1 
ATOM   6821 C CG  . ASN A 1 930  ? 179.017 184.164 176.920 1.00 256.15 ? 948  ASN A CG  1 
ATOM   6822 O OD1 . ASN A 1 930  ? 179.028 183.356 177.848 1.00 256.81 ? 948  ASN A OD1 1 
ATOM   6823 N ND2 . ASN A 1 930  ? 178.977 183.792 175.646 1.00 249.90 ? 948  ASN A ND2 1 
ATOM   6824 N N   . LEU A 1 931  ? 177.271 184.411 179.460 1.00 256.55 ? 949  LEU A N   1 
ATOM   6825 C CA  . LEU A 1 931  ? 175.981 184.054 180.040 1.00 253.84 ? 949  LEU A CA  1 
ATOM   6826 C C   . LEU A 1 931  ? 175.848 184.591 181.455 1.00 254.67 ? 949  LEU A C   1 
ATOM   6827 O O   . LEU A 1 931  ? 174.749 184.979 181.867 1.00 253.46 ? 949  LEU A O   1 
ATOM   6828 C CB  . LEU A 1 931  ? 175.794 182.537 180.039 1.00 250.29 ? 949  LEU A CB  1 
ATOM   6829 C CG  . LEU A 1 931  ? 175.432 181.882 178.704 1.00 248.79 ? 949  LEU A CG  1 
ATOM   6830 C CD1 . LEU A 1 931  ? 175.668 180.380 178.771 1.00 245.97 ? 949  LEU A CD1 1 
ATOM   6831 C CD2 . LEU A 1 931  ? 173.989 182.180 178.315 1.00 243.17 ? 949  LEU A CD2 1 
ATOM   6832 N N   . LYS A 1 932  ? 176.950 184.619 182.207 1.00 256.65 ? 950  LYS A N   1 
ATOM   6833 C CA  . LYS A 1 932  ? 176.920 185.170 183.557 1.00 256.51 ? 950  LYS A CA  1 
ATOM   6834 C C   . LYS A 1 932  ? 176.506 186.636 183.536 1.00 256.18 ? 950  LYS A C   1 
ATOM   6835 O O   . LYS A 1 932  ? 175.592 187.041 184.260 1.00 254.55 ? 950  LYS A O   1 
ATOM   6836 C CB  . LYS A 1 932  ? 178.291 184.998 184.216 1.00 253.56 ? 950  LYS A CB  1 
ATOM   6837 C CG  . LYS A 1 932  ? 178.370 185.458 185.669 1.00 248.11 ? 950  LYS A CG  1 
ATOM   6838 C CD  . LYS A 1 932  ? 179.758 185.228 186.244 1.00 248.78 ? 950  LYS A CD  1 
ATOM   6839 C CE  . LYS A 1 932  ? 179.928 185.927 187.583 1.00 250.10 ? 950  LYS A CE  1 
ATOM   6840 N NZ  . LYS A 1 932  ? 181.316 185.797 188.106 1.00 252.71 ? 950  LYS A NZ  1 
ATOM   6841 N N   . GLU A 1 933  ? 177.154 187.443 182.694 1.00 258.20 ? 951  GLU A N   1 
ATOM   6842 C CA  . GLU A 1 933  ? 176.809 188.858 182.623 1.00 258.22 ? 951  GLU A CA  1 
ATOM   6843 C C   . GLU A 1 933  ? 175.406 189.068 182.065 1.00 254.40 ? 951  GLU A C   1 
ATOM   6844 O O   . GLU A 1 933  ? 174.695 189.978 182.511 1.00 252.85 ? 951  GLU A O   1 
ATOM   6845 C CB  . GLU A 1 933  ? 177.839 189.608 181.777 1.00 261.76 ? 951  GLU A CB  1 
ATOM   6846 C CG  . GLU A 1 933  ? 179.213 189.730 182.431 1.00 262.92 ? 951  GLU A CG  1 
ATOM   6847 C CD  . GLU A 1 933  ? 179.216 190.647 183.642 1.00 265.63 ? 951  GLU A CD  1 
ATOM   6848 O OE1 . GLU A 1 933  ? 178.460 191.641 183.644 1.00 265.76 ? 951  GLU A OE1 1 
ATOM   6849 O OE2 . GLU A 1 933  ? 179.975 190.370 184.595 1.00 267.78 ? 951  GLU A OE2 1 
ATOM   6850 N N   . LYS A 1 934  ? 174.991 188.243 181.099 1.00 251.76 ? 952  LYS A N   1 
ATOM   6851 C CA  . LYS A 1 934  ? 173.636 188.348 180.567 1.00 248.90 ? 952  LYS A CA  1 
ATOM   6852 C C   . LYS A 1 934  ? 172.600 188.097 181.656 1.00 249.35 ? 952  LYS A C   1 
ATOM   6853 O O   . LYS A 1 934  ? 171.665 188.890 181.828 1.00 250.36 ? 952  LYS A O   1 
ATOM   6854 C CB  . LYS A 1 934  ? 173.472 187.366 179.400 1.00 246.99 ? 952  LYS A CB  1 
ATOM   6855 C CG  . LYS A 1 934  ? 172.038 187.026 178.977 1.00 245.25 ? 952  LYS A CG  1 
ATOM   6856 C CD  . LYS A 1 934  ? 172.047 186.120 177.754 1.00 243.96 ? 952  LYS A CD  1 
ATOM   6857 C CE  . LYS A 1 934  ? 170.684 185.494 177.497 1.00 243.26 ? 952  LYS A CE  1 
ATOM   6858 N NZ  . LYS A 1 934  ? 170.744 184.452 176.434 1.00 248.14 ? 952  LYS A NZ  1 
ATOM   6859 N N   . ALA A 1 935  ? 172.763 187.013 182.416 1.00 249.25 ? 953  ALA A N   1 
ATOM   6860 C CA  . ALA A 1 935  ? 171.831 186.721 183.497 1.00 249.84 ? 953  ALA A CA  1 
ATOM   6861 C C   . ALA A 1 935  ? 171.897 187.775 184.593 1.00 251.94 ? 953  ALA A C   1 
ATOM   6862 O O   . ALA A 1 935  ? 170.873 188.087 185.210 1.00 251.86 ? 953  ALA A O   1 
ATOM   6863 C CB  . ALA A 1 935  ? 172.116 185.337 184.077 1.00 249.72 ? 953  ALA A CB  1 
ATOM   6864 N N   . LEU A 1 936  ? 173.086 188.317 184.863 1.00 251.84 ? 954  LEU A N   1 
ATOM   6865 C CA  . LEU A 1 936  ? 173.203 189.362 185.875 1.00 251.12 ? 954  LEU A CA  1 
ATOM   6866 C C   . LEU A 1 936  ? 172.433 190.613 185.472 1.00 251.15 ? 954  LEU A C   1 
ATOM   6867 O O   . LEU A 1 936  ? 171.694 191.183 186.282 1.00 251.53 ? 954  LEU A O   1 
ATOM   6868 C CB  . LEU A 1 936  ? 174.674 189.690 186.136 1.00 247.75 ? 954  LEU A CB  1 
ATOM   6869 C CG  . LEU A 1 936  ? 175.355 189.009 187.337 1.00 243.52 ? 954  LEU A CG  1 
ATOM   6870 C CD1 . LEU A 1 936  ? 174.904 189.673 188.635 1.00 240.11 ? 954  LEU A CD1 1 
ATOM   6871 C CD2 . LEU A 1 936  ? 175.154 187.483 187.419 1.00 239.84 ? 954  LEU A CD2 1 
ATOM   6872 N N   . SER A 1 937  ? 172.577 191.045 184.219 1.00 250.66 ? 955  SER A N   1 
ATOM   6873 C CA  . SER A 1 937  ? 171.774 192.165 183.737 1.00 249.97 ? 955  SER A CA  1 
ATOM   6874 C C   . SER A 1 937  ? 170.289 191.834 183.804 1.00 253.18 ? 955  SER A C   1 
ATOM   6875 O O   . SER A 1 937  ? 169.471 192.681 184.198 1.00 253.55 ? 955  SER A O   1 
ATOM   6876 C CB  . SER A 1 937  ? 172.176 192.523 182.307 1.00 249.78 ? 955  SER A CB  1 
ATOM   6877 O OG  . SER A 1 937  ? 171.233 193.405 181.723 1.00 250.36 ? 955  SER A OG  1 
ATOM   6878 N N   . PHE A 1 938  ? 169.929 190.597 183.449 1.00 254.80 ? 956  PHE A N   1 
ATOM   6879 C CA  . PHE A 1 938  ? 168.524 190.208 183.428 1.00 253.60 ? 956  PHE A CA  1 
ATOM   6880 C C   . PHE A 1 938  ? 167.903 190.294 184.815 1.00 251.92 ? 956  PHE A C   1 
ATOM   6881 O O   . PHE A 1 938  ? 166.842 190.904 184.986 1.00 252.29 ? 956  PHE A O   1 
ATOM   6882 C CB  . PHE A 1 938  ? 168.375 188.784 182.872 1.00 250.72 ? 956  PHE A CB  1 
ATOM   6883 C CG  . PHE A 1 938  ? 168.466 188.662 181.353 1.00 250.74 ? 956  PHE A CG  1 
ATOM   6884 C CD1 . PHE A 1 938  ? 168.605 189.762 180.508 1.00 252.46 ? 956  PHE A CD1 1 
ATOM   6885 C CD2 . PHE A 1 938  ? 168.383 187.408 180.777 1.00 247.71 ? 956  PHE A CD2 1 
ATOM   6886 C CE1 . PHE A 1 938  ? 168.674 189.601 179.141 1.00 250.35 ? 956  PHE A CE1 1 
ATOM   6887 C CE2 . PHE A 1 938  ? 168.451 187.244 179.410 1.00 247.10 ? 956  PHE A CE2 1 
ATOM   6888 C CZ  . PHE A 1 938  ? 168.596 188.341 178.591 1.00 247.43 ? 956  PHE A CZ  1 
ATOM   6889 N N   . MET A 1 939  ? 168.550 189.711 185.829 1.00 250.89 ? 957  MET A N   1 
ATOM   6890 C CA  . MET A 1 939  ? 167.909 189.720 187.138 1.00 249.97 ? 957  MET A CA  1 
ATOM   6891 C C   . MET A 1 939  ? 168.107 191.052 187.851 1.00 249.94 ? 957  MET A C   1 
ATOM   6892 O O   . MET A 1 939  ? 167.333 191.360 188.756 1.00 246.80 ? 957  MET A O   1 
ATOM   6893 C CB  . MET A 1 939  ? 168.373 188.533 188.019 1.00 249.41 ? 957  MET A CB  1 
ATOM   6894 C CG  . MET A 1 939  ? 169.856 188.265 188.334 1.00 251.42 ? 957  MET A CG  1 
ATOM   6895 S SD  . MET A 1 939  ? 170.955 189.628 188.736 1.00 254.49 ? 957  MET A SD  1 
ATOM   6896 C CE  . MET A 1 939  ? 170.165 190.288 190.209 1.00 243.93 ? 957  MET A CE  1 
ATOM   6897 N N   . ARG A 1 940  ? 169.097 191.866 187.453 1.00 250.48 ? 958  ARG A N   1 
ATOM   6898 C CA  . ARG A 1 940  ? 169.123 193.251 187.918 1.00 248.57 ? 958  ARG A CA  1 
ATOM   6899 C C   . ARG A 1 940  ? 167.889 194.003 187.437 1.00 247.69 ? 958  ARG A C   1 
ATOM   6900 O O   . ARG A 1 940  ? 167.221 194.693 188.221 1.00 245.46 ? 958  ARG A O   1 
ATOM   6901 C CB  . ARG A 1 940  ? 170.389 193.956 187.426 1.00 247.01 ? 958  ARG A CB  1 
ATOM   6902 C CG  . ARG A 1 940  ? 171.627 193.733 188.279 1.00 245.06 ? 958  ARG A CG  1 
ATOM   6903 C CD  . ARG A 1 940  ? 172.813 194.514 187.727 1.00 245.07 ? 958  ARG A CD  1 
ATOM   6904 N NE  . ARG A 1 940  ? 174.096 193.932 188.124 1.00 245.36 ? 958  ARG A NE  1 
ATOM   6905 C CZ  . ARG A 1 940  ? 175.014 193.403 187.317 1.00 244.10 ? 958  ARG A CZ  1 
ATOM   6906 N NH1 . ARG A 1 940  ? 174.839 193.314 186.005 1.00 242.48 ? 958  ARG A NH1 1 
ATOM   6907 N NH2 . ARG A 1 940  ? 176.147 192.948 187.842 1.00 241.40 ? 958  ARG A NH2 1 
ATOM   6908 N N   . GLN A 1 941  ? 167.562 193.867 186.149 1.00 249.71 ? 959  GLN A N   1 
ATOM   6909 C CA  . GLN A 1 941  ? 166.350 194.488 185.629 1.00 248.64 ? 959  GLN A CA  1 
ATOM   6910 C C   . GLN A 1 941  ? 165.102 193.904 186.279 1.00 245.43 ? 959  GLN A C   1 
ATOM   6911 O O   . GLN A 1 941  ? 164.143 194.636 186.545 1.00 241.86 ? 959  GLN A O   1 
ATOM   6912 C CB  . GLN A 1 941  ? 166.289 194.319 184.113 1.00 250.75 ? 959  GLN A CB  1 
ATOM   6913 C CG  . GLN A 1 941  ? 167.172 195.292 183.352 1.00 252.25 ? 959  GLN A CG  1 
ATOM   6914 C CD  . GLN A 1 941  ? 167.546 194.781 181.976 1.00 256.17 ? 959  GLN A CD  1 
ATOM   6915 O OE1 . GLN A 1 941  ? 168.496 194.013 181.824 1.00 256.92 ? 959  GLN A OE1 1 
ATOM   6916 N NE2 . GLN A 1 941  ? 166.799 195.207 180.964 1.00 256.67 ? 959  GLN A NE2 1 
ATOM   6917 N N   . GLY A 1 942  ? 165.093 192.596 186.538 1.00 246.79 ? 960  GLY A N   1 
ATOM   6918 C CA  . GLY A 1 942  ? 163.958 191.992 187.218 1.00 243.31 ? 960  GLY A CA  1 
ATOM   6919 C C   . GLY A 1 942  ? 163.793 192.498 188.639 1.00 240.17 ? 960  GLY A C   1 
ATOM   6920 O O   . GLY A 1 942  ? 162.672 192.710 189.106 1.00 238.86 ? 960  GLY A O   1 
ATOM   6921 N N   . TYR A 1 943  ? 164.907 192.688 189.348 1.00 240.16 ? 961  TYR A N   1 
ATOM   6922 C CA  . TYR A 1 943  ? 164.861 193.265 190.685 1.00 238.75 ? 961  TYR A CA  1 
ATOM   6923 C C   . TYR A 1 943  ? 164.322 194.687 190.645 1.00 238.83 ? 961  TYR A C   1 
ATOM   6924 O O   . TYR A 1 943  ? 163.530 195.081 191.506 1.00 235.90 ? 961  TYR A O   1 
ATOM   6925 C CB  . TYR A 1 943  ? 166.258 193.235 191.304 1.00 236.28 ? 961  TYR A CB  1 
ATOM   6926 C CG  . TYR A 1 943  ? 166.358 193.878 192.670 1.00 234.95 ? 961  TYR A CG  1 
ATOM   6927 C CD1 . TYR A 1 943  ? 165.513 193.500 193.705 1.00 235.28 ? 961  TYR A CD1 1 
ATOM   6928 C CD2 . TYR A 1 943  ? 167.307 194.859 192.926 1.00 232.63 ? 961  TYR A CD2 1 
ATOM   6929 C CE1 . TYR A 1 943  ? 165.607 194.084 194.954 1.00 235.21 ? 961  TYR A CE1 1 
ATOM   6930 C CE2 . TYR A 1 943  ? 167.408 195.449 194.172 1.00 231.87 ? 961  TYR A CE2 1 
ATOM   6931 C CZ  . TYR A 1 943  ? 166.556 195.058 195.182 1.00 232.05 ? 961  TYR A CZ  1 
ATOM   6932 O OH  . TYR A 1 943  ? 166.654 195.643 196.424 1.00 225.36 ? 961  TYR A OH  1 
ATOM   6933 N N   . GLN A 1 944  ? 164.739 195.471 189.648 1.00 241.52 ? 962  GLN A N   1 
ATOM   6934 C CA  . GLN A 1 944  ? 164.189 196.816 189.498 1.00 240.71 ? 962  GLN A CA  1 
ATOM   6935 C C   . GLN A 1 944  ? 162.689 196.773 189.217 1.00 237.30 ? 962  GLN A C   1 
ATOM   6936 O O   . GLN A 1 944  ? 161.919 197.560 189.783 1.00 235.40 ? 962  GLN A O   1 
ATOM   6937 C CB  . GLN A 1 944  ? 164.925 197.552 188.381 1.00 243.83 ? 962  GLN A CB  1 
ATOM   6938 C CG  . GLN A 1 944  ? 166.324 198.023 188.775 1.00 244.48 ? 962  GLN A CG  1 
ATOM   6939 C CD  . GLN A 1 944  ? 167.278 198.151 187.596 1.00 247.00 ? 962  GLN A CD  1 
ATOM   6940 O OE1 . GLN A 1 944  ? 166.897 197.965 186.440 1.00 249.07 ? 962  GLN A OE1 1 
ATOM   6941 N NE2 . GLN A 1 944  ? 168.532 198.474 187.891 1.00 244.06 ? 962  GLN A NE2 1 
ATOM   6942 N N   . ARG A 1 945  ? 162.257 195.856 188.349 1.00 237.46 ? 963  ARG A N   1 
ATOM   6943 C CA  . ARG A 1 945  ? 160.839 195.754 188.022 1.00 235.67 ? 963  ARG A CA  1 
ATOM   6944 C C   . ARG A 1 945  ? 160.016 195.306 189.223 1.00 235.64 ? 963  ARG A C   1 
ATOM   6945 O O   . ARG A 1 945  ? 158.874 195.747 189.390 1.00 234.46 ? 963  ARG A O   1 
ATOM   6946 C CB  . ARG A 1 945  ? 160.640 194.788 186.855 1.00 237.50 ? 963  ARG A CB  1 
ATOM   6947 C CG  . ARG A 1 945  ? 159.303 194.944 186.146 1.00 236.13 ? 963  ARG A CG  1 
ATOM   6948 C CD  . ARG A 1 945  ? 159.131 193.918 185.036 1.00 244.40 ? 963  ARG A CD  1 
ATOM   6949 N NE  . ARG A 1 945  ? 160.150 194.065 183.996 1.00 248.73 ? 963  ARG A NE  1 
ATOM   6950 C CZ  . ARG A 1 945  ? 159.955 194.465 182.742 1.00 250.24 ? 963  ARG A CZ  1 
ATOM   6951 N NH1 . ARG A 1 945  ? 158.761 194.826 182.291 1.00 250.08 ? 963  ARG A NH1 1 
ATOM   6952 N NH2 . ARG A 1 945  ? 160.993 194.511 181.913 1.00 248.74 ? 963  ARG A NH2 1 
ATOM   6953 N N   . GLU A 1 946  ? 160.569 194.425 190.057 1.00 236.53 ? 964  GLU A N   1 
ATOM   6954 C CA  . GLU A 1 946  ? 159.866 194.021 191.269 1.00 239.28 ? 964  GLU A CA  1 
ATOM   6955 C C   . GLU A 1 946  ? 159.863 195.140 192.300 1.00 238.94 ? 964  GLU A C   1 
ATOM   6956 O O   . GLU A 1 946  ? 158.910 195.263 193.078 1.00 238.34 ? 964  GLU A O   1 
ATOM   6957 C CB  . GLU A 1 946  ? 160.506 192.757 191.850 1.00 242.88 ? 964  GLU A CB  1 
ATOM   6958 C CG  . GLU A 1 946  ? 159.532 191.764 192.491 1.00 246.57 ? 964  GLU A CG  1 
ATOM   6959 C CD  . GLU A 1 946  ? 158.537 191.175 191.504 1.00 247.53 ? 964  GLU A CD  1 
ATOM   6960 O OE1 . GLU A 1 946  ? 158.953 190.808 190.385 1.00 250.80 ? 964  GLU A OE1 1 
ATOM   6961 O OE2 . GLU A 1 946  ? 157.341 191.080 191.849 1.00 245.69 ? 964  GLU A OE2 1 
ATOM   6962 N N   . LEU A 1 947  ? 160.915 195.963 192.321 1.00 237.86 ? 965  LEU A N   1 
ATOM   6963 C CA  . LEU A 1 947  ? 160.901 197.160 193.152 1.00 236.06 ? 965  LEU A CA  1 
ATOM   6964 C C   . LEU A 1 947  ? 159.798 198.113 192.716 1.00 234.29 ? 965  LEU A C   1 
ATOM   6965 O O   . LEU A 1 947  ? 159.172 198.762 193.560 1.00 230.59 ? 965  LEU A O   1 
ATOM   6966 C CB  . LEU A 1 947  ? 162.259 197.863 193.091 1.00 235.20 ? 965  LEU A CB  1 
ATOM   6967 C CG  . LEU A 1 947  ? 163.401 197.314 193.951 1.00 232.15 ? 965  LEU A CG  1 
ATOM   6968 C CD1 . LEU A 1 947  ? 164.699 198.033 193.611 1.00 229.74 ? 965  LEU A CD1 1 
ATOM   6969 C CD2 . LEU A 1 947  ? 163.097 197.446 195.437 1.00 230.85 ? 965  LEU A CD2 1 
ATOM   6970 N N   . LEU A 1 948  ? 159.552 198.213 191.406 1.00 235.96 ? 966  LEU A N   1 
ATOM   6971 C CA  . LEU A 1 948  ? 158.423 199.009 190.935 1.00 235.94 ? 966  LEU A CA  1 
ATOM   6972 C C   . LEU A 1 948  ? 157.098 198.447 191.437 1.00 235.14 ? 966  LEU A C   1 
ATOM   6973 O O   . LEU A 1 948  ? 156.170 199.214 191.719 1.00 234.26 ? 966  LEU A O   1 
ATOM   6974 C CB  . LEU A 1 948  ? 158.414 199.074 189.406 1.00 236.83 ? 966  LEU A CB  1 
ATOM   6975 C CG  . LEU A 1 948  ? 159.554 199.832 188.720 1.00 235.06 ? 966  LEU A CG  1 
ATOM   6976 C CD1 . LEU A 1 948  ? 159.508 199.605 187.215 1.00 231.64 ? 966  LEU A CD1 1 
ATOM   6977 C CD2 . LEU A 1 948  ? 159.494 201.319 189.034 1.00 232.73 ? 966  LEU A CD2 1 
ATOM   6978 N N   . TYR A 1 949  ? 156.992 197.125 191.561 1.00 235.46 ? 967  TYR A N   1 
ATOM   6979 C CA  . TYR A 1 949  ? 155.782 196.470 192.044 1.00 234.37 ? 967  TYR A CA  1 
ATOM   6980 C C   . TYR A 1 949  ? 155.732 196.337 193.563 1.00 232.34 ? 967  TYR A C   1 
ATOM   6981 O O   . TYR A 1 949  ? 154.755 195.791 194.085 1.00 232.05 ? 967  TYR A O   1 
ATOM   6982 C CB  . TYR A 1 949  ? 155.652 195.077 191.410 1.00 235.83 ? 967  TYR A CB  1 
ATOM   6983 C CG  . TYR A 1 949  ? 155.283 195.069 189.937 1.00 238.68 ? 967  TYR A CG  1 
ATOM   6984 C CD1 . TYR A 1 949  ? 154.145 195.721 189.475 1.00 240.61 ? 967  TYR A CD1 1 
ATOM   6985 C CD2 . TYR A 1 949  ? 156.076 194.408 189.009 1.00 239.46 ? 967  TYR A CD2 1 
ATOM   6986 C CE1 . TYR A 1 949  ? 153.809 195.713 188.136 1.00 241.34 ? 967  TYR A CE1 1 
ATOM   6987 C CE2 . TYR A 1 949  ? 155.748 194.396 187.667 1.00 240.33 ? 967  TYR A CE2 1 
ATOM   6988 C CZ  . TYR A 1 949  ? 154.613 195.050 187.237 1.00 240.18 ? 967  TYR A CZ  1 
ATOM   6989 O OH  . TYR A 1 949  ? 154.282 195.041 185.902 1.00 237.62 ? 967  TYR A OH  1 
ATOM   6990 N N   . GLN A 1 950  ? 156.742 196.816 194.285 1.00 231.13 ? 968  GLN A N   1 
ATOM   6991 C CA  . GLN A 1 950  ? 156.721 196.794 195.741 1.00 233.23 ? 968  GLN A CA  1 
ATOM   6992 C C   . GLN A 1 950  ? 155.867 197.944 196.256 1.00 236.00 ? 968  GLN A C   1 
ATOM   6993 O O   . GLN A 1 950  ? 155.945 199.063 195.738 1.00 236.66 ? 968  GLN A O   1 
ATOM   6994 C CB  . GLN A 1 950  ? 158.135 196.899 196.309 1.00 233.16 ? 968  GLN A CB  1 
ATOM   6995 C CG  . GLN A 1 950  ? 158.179 196.838 197.836 1.00 237.14 ? 968  GLN A CG  1 
ATOM   6996 C CD  . GLN A 1 950  ? 159.556 196.535 198.439 1.00 238.96 ? 968  GLN A CD  1 
ATOM   6997 O OE1 . GLN A 1 950  ? 159.634 196.159 199.608 1.00 238.18 ? 968  GLN A OE1 1 
ATOM   6998 N NE2 . GLN A 1 950  ? 160.637 196.724 197.674 1.00 238.62 ? 968  GLN A NE2 1 
ATOM   6999 N N   . ARG A 1 951  ? 155.060 197.665 197.278 1.00 238.89 ? 969  ARG A N   1 
ATOM   7000 C CA  . ARG A 1 951  ? 154.200 198.666 197.885 1.00 242.86 ? 969  ARG A CA  1 
ATOM   7001 C C   . ARG A 1 951  ? 154.899 199.323 199.074 1.00 247.10 ? 969  ARG A C   1 
ATOM   7002 O O   . ARG A 1 951  ? 155.997 198.936 199.482 1.00 246.14 ? 969  ARG A O   1 
ATOM   7003 C CB  . ARG A 1 951  ? 152.877 198.040 198.316 1.00 241.55 ? 969  ARG A CB  1 
ATOM   7004 C CG  . ARG A 1 951  ? 152.134 197.333 197.203 1.00 240.78 ? 969  ARG A CG  1 
ATOM   7005 C CD  . ARG A 1 951  ? 150.651 197.286 197.506 1.00 240.39 ? 969  ARG A CD  1 
ATOM   7006 N NE  . ARG A 1 951  ? 149.959 196.247 196.754 1.00 243.08 ? 969  ARG A NE  1 
ATOM   7007 C CZ  . ARG A 1 951  ? 148.724 195.829 196.999 1.00 242.41 ? 969  ARG A CZ  1 
ATOM   7008 N NH1 . ARG A 1 951  ? 148.002 196.326 197.993 1.00 238.65 ? 969  ARG A NH1 1 
ATOM   7009 N NH2 . ARG A 1 951  ? 148.195 194.885 196.226 1.00 243.73 ? 969  ARG A NH2 1 
ATOM   7010 N N   . GLU A 1 952  ? 154.242 200.335 199.642 1.00 251.97 ? 970  GLU A N   1 
ATOM   7011 C CA  . GLU A 1 952  ? 154.795 201.062 200.779 1.00 255.23 ? 970  GLU A CA  1 
ATOM   7012 C C   . GLU A 1 952  ? 154.906 200.204 202.033 1.00 254.79 ? 970  GLU A C   1 
ATOM   7013 O O   . GLU A 1 952  ? 155.801 200.444 202.851 1.00 256.27 ? 970  GLU A O   1 
ATOM   7014 C CB  . GLU A 1 952  ? 153.954 202.321 201.060 1.00 255.07 ? 970  GLU A CB  1 
ATOM   7015 C CG  . GLU A 1 952  ? 152.549 202.122 201.689 1.00 252.61 ? 970  GLU A CG  1 
ATOM   7016 C CD  . GLU A 1 952  ? 151.505 201.617 200.707 1.00 250.69 ? 970  GLU A CD  1 
ATOM   7017 O OE1 . GLU A 1 952  ? 151.742 201.687 199.483 1.00 249.42 ? 970  GLU A OE1 1 
ATOM   7018 O OE2 . GLU A 1 952  ? 150.442 201.146 201.164 1.00 251.08 ? 970  GLU A OE2 1 
ATOM   7019 N N   . ASP A 1 953  ? 154.031 199.215 202.201 1.00 253.07 ? 971  ASP A N   1 
ATOM   7020 C CA  . ASP A 1 953  ? 154.052 198.336 203.364 1.00 248.79 ? 971  ASP A CA  1 
ATOM   7021 C C   . ASP A 1 953  ? 154.929 197.104 203.164 1.00 245.95 ? 971  ASP A C   1 
ATOM   7022 O O   . ASP A 1 953  ? 154.941 196.224 204.030 1.00 241.52 ? 971  ASP A O   1 
ATOM   7023 C CB  . ASP A 1 953  ? 152.629 197.894 203.724 1.00 245.26 ? 971  ASP A CB  1 
ATOM   7024 C CG  . ASP A 1 953  ? 151.962 197.096 202.616 1.00 243.58 ? 971  ASP A CG  1 
ATOM   7025 O OD1 . ASP A 1 953  ? 152.464 197.124 201.473 1.00 245.46 ? 971  ASP A OD1 1 
ATOM   7026 O OD2 . ASP A 1 953  ? 150.937 196.439 202.891 1.00 238.83 ? 971  ASP A OD2 1 
ATOM   7027 N N   . GLY A 1 954  ? 155.658 197.018 202.050 1.00 246.88 ? 972  GLY A N   1 
ATOM   7028 C CA  . GLY A 1 954  ? 156.448 195.849 201.737 1.00 243.58 ? 972  GLY A CA  1 
ATOM   7029 C C   . GLY A 1 954  ? 155.696 194.740 201.036 1.00 241.78 ? 972  GLY A C   1 
ATOM   7030 O O   . GLY A 1 954  ? 156.317 193.739 200.657 1.00 240.94 ? 972  GLY A O   1 
ATOM   7031 N N   . SER A 1 955  ? 154.386 194.880 200.850 1.00 242.81 ? 973  SER A N   1 
ATOM   7032 C CA  . SER A 1 955  ? 153.621 193.862 200.154 1.00 242.53 ? 973  SER A CA  1 
ATOM   7033 C C   . SER A 1 955  ? 153.969 193.861 198.669 1.00 243.03 ? 973  SER A C   1 
ATOM   7034 O O   . SER A 1 955  ? 154.482 194.841 198.121 1.00 240.81 ? 973  SER A O   1 
ATOM   7035 C CB  . SER A 1 955  ? 152.122 194.096 200.338 1.00 241.59 ? 973  SER A CB  1 
ATOM   7036 O OG  . SER A 1 955  ? 151.714 195.298 199.715 1.00 239.95 ? 973  SER A OG  1 
ATOM   7037 N N   . PHE A 1 956  ? 153.683 192.732 198.021 1.00 243.78 ? 974  PHE A N   1 
ATOM   7038 C CA  . PHE A 1 956  ? 153.957 192.535 196.606 1.00 243.62 ? 974  PHE A CA  1 
ATOM   7039 C C   . PHE A 1 956  ? 152.723 191.963 195.924 1.00 244.39 ? 974  PHE A C   1 
ATOM   7040 O O   . PHE A 1 956  ? 151.945 191.220 196.528 1.00 243.05 ? 974  PHE A O   1 
ATOM   7041 C CB  . PHE A 1 956  ? 155.153 191.601 196.398 1.00 242.88 ? 974  PHE A CB  1 
ATOM   7042 C CG  . PHE A 1 956  ? 156.480 192.263 196.630 1.00 244.22 ? 974  PHE A CG  1 
ATOM   7043 C CD1 . PHE A 1 956  ? 156.964 192.440 197.915 1.00 244.15 ? 974  PHE A CD1 1 
ATOM   7044 C CD2 . PHE A 1 956  ? 157.243 192.710 195.564 1.00 243.06 ? 974  PHE A CD2 1 
ATOM   7045 C CE1 . PHE A 1 956  ? 158.184 193.050 198.132 1.00 244.34 ? 974  PHE A CE1 1 
ATOM   7046 C CE2 . PHE A 1 956  ? 158.463 193.319 195.776 1.00 242.14 ? 974  PHE A CE2 1 
ATOM   7047 C CZ  . PHE A 1 956  ? 158.935 193.490 197.061 1.00 243.34 ? 974  PHE A CZ  1 
ATOM   7048 N N   . SER A 1 957  ? 152.555 192.324 194.654 1.00 245.57 ? 975  SER A N   1 
ATOM   7049 C CA  . SER A 1 957  ? 151.416 191.885 193.863 1.00 246.72 ? 975  SER A CA  1 
ATOM   7050 C C   . SER A 1 957  ? 151.813 191.922 192.393 1.00 247.43 ? 975  SER A C   1 
ATOM   7051 O O   . SER A 1 957  ? 152.880 192.426 192.030 1.00 246.25 ? 975  SER A O   1 
ATOM   7052 C CB  . SER A 1 957  ? 150.187 192.757 194.141 1.00 247.16 ? 975  SER A CB  1 
ATOM   7053 O OG  . SER A 1 957  ? 150.010 193.735 193.131 1.00 248.95 ? 975  SER A OG  1 
ATOM   7054 N N   . ALA A 1 958  ? 150.942 191.372 191.544 1.00 247.38 ? 976  ALA A N   1 
ATOM   7055 C CA  . ALA A 1 958  ? 151.223 191.340 190.112 1.00 248.52 ? 976  ALA A CA  1 
ATOM   7056 C C   . ALA A 1 958  ? 151.324 192.746 189.537 1.00 248.28 ? 976  ALA A C   1 
ATOM   7057 O O   . ALA A 1 958  ? 152.234 193.037 188.751 1.00 246.72 ? 976  ALA A O   1 
ATOM   7058 C CB  . ALA A 1 958  ? 150.140 190.545 189.385 1.00 249.96 ? 976  ALA A CB  1 
ATOM   7059 N N   . PHE A 1 959  ? 150.402 193.629 189.925 1.00 249.40 ? 977  PHE A N   1 
ATOM   7060 C CA  . PHE A 1 959  ? 150.369 195.015 189.473 1.00 248.38 ? 977  PHE A CA  1 
ATOM   7061 C C   . PHE A 1 959  ? 150.795 195.997 190.559 1.00 248.25 ? 977  PHE A C   1 
ATOM   7062 O O   . PHE A 1 959  ? 150.568 197.202 190.412 1.00 247.25 ? 977  PHE A O   1 
ATOM   7063 C CB  . PHE A 1 959  ? 148.963 195.363 188.977 1.00 246.48 ? 977  PHE A CB  1 
ATOM   7064 C CG  . PHE A 1 959  ? 148.492 194.513 187.827 1.00 245.27 ? 977  PHE A CG  1 
ATOM   7065 C CD1 . PHE A 1 959  ? 149.228 194.424 186.656 1.00 242.77 ? 977  PHE A CD1 1 
ATOM   7066 C CD2 . PHE A 1 959  ? 147.308 193.800 187.920 1.00 244.21 ? 977  PHE A CD2 1 
ATOM   7067 C CE1 . PHE A 1 959  ? 148.793 193.642 185.603 1.00 239.47 ? 977  PHE A CE1 1 
ATOM   7068 C CE2 . PHE A 1 959  ? 146.868 193.017 186.871 1.00 242.36 ? 977  PHE A CE2 1 
ATOM   7069 C CZ  . PHE A 1 959  ? 147.612 192.938 185.711 1.00 239.60 ? 977  PHE A CZ  1 
ATOM   7070 N N   . GLY A 1 960  ? 151.406 195.518 191.642 1.00 247.86 ? 978  GLY A N   1 
ATOM   7071 C CA  . GLY A 1 960  ? 151.847 196.394 192.708 1.00 245.21 ? 978  GLY A CA  1 
ATOM   7072 C C   . GLY A 1 960  ? 150.710 197.093 193.423 1.00 246.24 ? 978  GLY A C   1 
ATOM   7073 O O   . GLY A 1 960  ? 149.786 196.443 193.922 1.00 247.74 ? 978  GLY A O   1 
ATOM   7074 N N   . ASN A 1 961  ? 150.765 198.424 193.473 1.00 245.49 ? 979  ASN A N   1 
ATOM   7075 C CA  . ASN A 1 961  ? 149.775 199.204 194.204 1.00 245.74 ? 979  ASN A CA  1 
ATOM   7076 C C   . ASN A 1 961  ? 148.411 199.231 193.528 1.00 244.16 ? 979  ASN A C   1 
ATOM   7077 O O   . ASN A 1 961  ? 147.424 199.569 194.190 1.00 241.79 ? 979  ASN A O   1 
ATOM   7078 C CB  . ASN A 1 961  ? 150.274 200.639 194.390 1.00 244.51 ? 979  ASN A CB  1 
ATOM   7079 C CG  . ASN A 1 961  ? 151.253 200.770 195.540 1.00 242.84 ? 979  ASN A CG  1 
ATOM   7080 O OD1 . ASN A 1 961  ? 150.904 200.533 196.696 1.00 242.37 ? 979  ASN A OD1 1 
ATOM   7081 N ND2 . ASN A 1 961  ? 152.487 201.150 195.229 1.00 240.77 ? 979  ASN A ND2 1 
ATOM   7082 N N   . TYR A 1 962  ? 148.326 198.893 192.239 1.00 244.03 ? 980  TYR A N   1 
ATOM   7083 C CA  . TYR A 1 962  ? 147.027 198.865 191.575 1.00 242.96 ? 980  TYR A CA  1 
ATOM   7084 C C   . TYR A 1 962  ? 146.126 197.795 192.179 1.00 244.45 ? 980  TYR A C   1 
ATOM   7085 O O   . TYR A 1 962  ? 144.919 198.012 192.338 1.00 241.60 ? 980  TYR A O   1 
ATOM   7086 C CB  . TYR A 1 962  ? 147.202 198.636 190.072 1.00 239.51 ? 980  TYR A CB  1 
ATOM   7087 C CG  . TYR A 1 962  ? 148.087 199.650 189.367 1.00 236.85 ? 980  TYR A CG  1 
ATOM   7088 C CD1 . TYR A 1 962  ? 148.053 200.998 189.707 1.00 234.27 ? 980  TYR A CD1 1 
ATOM   7089 C CD2 . TYR A 1 962  ? 148.950 199.258 188.352 1.00 237.17 ? 980  TYR A CD2 1 
ATOM   7090 C CE1 . TYR A 1 962  ? 148.856 201.920 189.063 1.00 232.15 ? 980  TYR A CE1 1 
ATOM   7091 C CE2 . TYR A 1 962  ? 149.756 200.173 187.703 1.00 234.13 ? 980  TYR A CE2 1 
ATOM   7092 C CZ  . TYR A 1 962  ? 149.705 201.502 188.062 1.00 231.66 ? 980  TYR A CZ  1 
ATOM   7093 O OH  . TYR A 1 962  ? 150.506 202.416 187.417 1.00 225.93 ? 980  TYR A OH  1 
ATOM   7094 N N   . ASP A 1 963  ? 146.687 196.639 192.520 1.00 247.15 ? 981  ASP A N   1 
ATOM   7095 C CA  . ASP A 1 963  ? 145.904 195.617 193.189 1.00 245.38 ? 981  ASP A CA  1 
ATOM   7096 C C   . ASP A 1 963  ? 145.540 196.085 194.600 1.00 242.30 ? 981  ASP A C   1 
ATOM   7097 O O   . ASP A 1 963  ? 146.287 196.851 195.216 1.00 240.12 ? 981  ASP A O   1 
ATOM   7098 C CB  . ASP A 1 963  ? 146.679 194.303 193.254 1.00 245.84 ? 981  ASP A CB  1 
ATOM   7099 C CG  . ASP A 1 963  ? 146.968 193.729 191.881 1.00 247.04 ? 981  ASP A CG  1 
ATOM   7100 O OD1 . ASP A 1 963  ? 146.142 193.926 190.966 1.00 245.41 ? 981  ASP A OD1 1 
ATOM   7101 O OD2 . ASP A 1 963  ? 148.021 193.079 191.718 1.00 247.77 ? 981  ASP A OD2 1 
ATOM   7102 N N   . PRO A 1 964  ? 144.391 195.639 195.147 1.00 242.36 ? 982  PRO A N   1 
ATOM   7103 C CA  . PRO A 1 964  ? 143.942 196.208 196.425 1.00 241.95 ? 982  PRO A CA  1 
ATOM   7104 C C   . PRO A 1 964  ? 144.659 195.628 197.635 1.00 240.79 ? 982  PRO A C   1 
ATOM   7105 O O   . PRO A 1 964  ? 144.813 196.317 198.649 1.00 234.45 ? 982  PRO A O   1 
ATOM   7106 C CB  . PRO A 1 964  ? 142.445 195.874 196.456 1.00 239.84 ? 982  PRO A CB  1 
ATOM   7107 C CG  . PRO A 1 964  ? 142.242 194.769 195.463 1.00 239.14 ? 982  PRO A CG  1 
ATOM   7108 C CD  . PRO A 1 964  ? 143.522 194.528 194.717 1.00 240.68 ? 982  PRO A CD  1 
ATOM   7109 N N   . SER A 1 965  ? 145.097 194.372 197.549 1.00 243.48 ? 983  SER A N   1 
ATOM   7110 C CA  . SER A 1 965  ? 145.770 193.706 198.658 1.00 243.52 ? 983  SER A CA  1 
ATOM   7111 C C   . SER A 1 965  ? 146.784 192.714 198.112 1.00 247.83 ? 983  SER A C   1 
ATOM   7112 O O   . SER A 1 965  ? 146.483 191.966 197.177 1.00 246.99 ? 983  SER A O   1 
ATOM   7113 C CB  . SER A 1 965  ? 144.762 192.989 199.563 1.00 240.91 ? 983  SER A CB  1 
ATOM   7114 O OG  . SER A 1 965  ? 145.407 192.426 200.692 1.00 241.64 ? 983  SER A OG  1 
ATOM   7115 N N   . GLY A 1 966  ? 147.980 192.712 198.697 1.00 249.26 ? 984  GLY A N   1 
ATOM   7116 C CA  . GLY A 1 966  ? 149.018 191.811 198.249 1.00 249.25 ? 984  GLY A CA  1 
ATOM   7117 C C   . GLY A 1 966  ? 148.785 190.384 198.706 1.00 250.10 ? 984  GLY A C   1 
ATOM   7118 O O   . GLY A 1 966  ? 147.936 190.097 199.552 1.00 250.28 ? 984  GLY A O   1 
ATOM   7119 N N   . SER A 1 967  ? 149.568 189.476 198.126 1.00 247.71 ? 985  SER A N   1 
ATOM   7120 C CA  . SER A 1 967  ? 149.479 188.048 198.404 1.00 243.67 ? 985  SER A CA  1 
ATOM   7121 C C   . SER A 1 967  ? 150.646 187.619 199.282 1.00 239.10 ? 985  SER A C   1 
ATOM   7122 O O   . SER A 1 967  ? 151.808 187.873 198.948 1.00 236.80 ? 985  SER A O   1 
ATOM   7123 C CB  . SER A 1 967  ? 149.479 187.242 197.104 1.00 242.62 ? 985  SER A CB  1 
ATOM   7124 O OG  . SER A 1 967  ? 150.116 185.990 197.283 1.00 238.23 ? 985  SER A OG  1 
ATOM   7125 N N   . THR A 1 968  ? 150.331 186.965 200.402 1.00 237.74 ? 986  THR A N   1 
ATOM   7126 C CA  . THR A 1 968  ? 151.385 186.473 201.284 1.00 233.39 ? 986  THR A CA  1 
ATOM   7127 C C   . THR A 1 968  ? 152.179 185.352 200.630 1.00 229.59 ? 986  THR A C   1 
ATOM   7128 O O   . THR A 1 968  ? 153.381 185.224 200.880 1.00 228.20 ? 986  THR A O   1 
ATOM   7129 C CB  . THR A 1 968  ? 150.802 185.982 202.612 1.00 233.55 ? 986  THR A CB  1 
ATOM   7130 O OG1 . THR A 1 968  ? 149.809 184.976 202.372 1.00 231.36 ? 986  THR A OG1 1 
ATOM   7131 C CG2 . THR A 1 968  ? 150.193 187.138 203.402 1.00 237.09 ? 986  THR A CG2 1 
ATOM   7132 N N   . TRP A 1 969  ? 151.533 184.526 199.805 1.00 227.89 ? 987  TRP A N   1 
ATOM   7133 C CA  . TRP A 1 969  ? 152.260 183.470 199.110 1.00 226.83 ? 987  TRP A CA  1 
ATOM   7134 C C   . TRP A 1 969  ? 153.241 184.056 198.101 1.00 229.12 ? 987  TRP A C   1 
ATOM   7135 O O   . TRP A 1 969  ? 154.408 183.648 198.048 1.00 229.61 ? 987  TRP A O   1 
ATOM   7136 C CB  . TRP A 1 969  ? 151.274 182.528 198.420 1.00 222.01 ? 987  TRP A CB  1 
ATOM   7137 C CG  . TRP A 1 969  ? 151.925 181.378 197.724 1.00 220.70 ? 987  TRP A CG  1 
ATOM   7138 C CD1 . TRP A 1 969  ? 152.258 180.173 198.269 1.00 218.15 ? 987  TRP A CD1 1 
ATOM   7139 C CD2 . TRP A 1 969  ? 152.325 181.320 196.350 1.00 221.72 ? 987  TRP A CD2 1 
ATOM   7140 N NE1 . TRP A 1 969  ? 152.839 179.368 197.321 1.00 216.43 ? 987  TRP A NE1 1 
ATOM   7141 C CE2 . TRP A 1 969  ? 152.893 180.050 196.134 1.00 219.88 ? 987  TRP A CE2 1 
ATOM   7142 C CE3 . TRP A 1 969  ? 152.259 182.220 195.283 1.00 222.18 ? 987  TRP A CE3 1 
ATOM   7143 C CZ2 . TRP A 1 969  ? 153.390 179.656 194.895 1.00 221.62 ? 987  TRP A CZ2 1 
ATOM   7144 C CZ3 . TRP A 1 969  ? 152.754 181.828 194.054 1.00 223.09 ? 987  TRP A CZ3 1 
ATOM   7145 C CH2 . TRP A 1 969  ? 153.312 180.557 193.870 1.00 221.45 ? 987  TRP A CH2 1 
ATOM   7146 N N   . LEU A 1 970  ? 152.789 185.026 197.303 1.00 229.68 ? 988  LEU A N   1 
ATOM   7147 C CA  . LEU A 1 970  ? 153.694 185.709 196.386 1.00 231.06 ? 988  LEU A CA  1 
ATOM   7148 C C   . LEU A 1 970  ? 154.761 186.487 197.141 1.00 233.43 ? 988  LEU A C   1 
ATOM   7149 O O   . LEU A 1 970  ? 155.909 186.569 196.686 1.00 233.19 ? 988  LEU A O   1 
ATOM   7150 C CB  . LEU A 1 970  ? 152.903 186.645 195.473 1.00 234.38 ? 988  LEU A CB  1 
ATOM   7151 C CG  . LEU A 1 970  ? 153.666 187.224 194.280 1.00 234.77 ? 988  LEU A CG  1 
ATOM   7152 C CD1 . LEU A 1 970  ? 152.898 186.991 192.988 1.00 235.82 ? 988  LEU A CD1 1 
ATOM   7153 C CD2 . LEU A 1 970  ? 153.937 188.706 194.484 1.00 237.62 ? 988  LEU A CD2 1 
ATOM   7154 N N   . SER A 1 971  ? 154.400 187.067 198.289 1.00 235.12 ? 989  SER A N   1 
ATOM   7155 C CA  . SER A 1 971  ? 155.382 187.762 199.112 1.00 235.77 ? 989  SER A CA  1 
ATOM   7156 C C   . SER A 1 971  ? 156.470 186.809 199.589 1.00 232.68 ? 989  SER A C   1 
ATOM   7157 O O   . SER A 1 971  ? 157.658 187.143 199.547 1.00 230.89 ? 989  SER A O   1 
ATOM   7158 C CB  . SER A 1 971  ? 154.688 188.424 200.301 1.00 236.20 ? 989  SER A CB  1 
ATOM   7159 O OG  . SER A 1 971  ? 153.795 189.435 199.867 1.00 236.65 ? 989  SER A OG  1 
ATOM   7160 N N   . ALA A 1 972  ? 156.085 185.611 200.032 1.00 231.62 ? 990  ALA A N   1 
ATOM   7161 C CA  . ALA A 1 972  ? 157.070 184.620 200.452 1.00 230.87 ? 990  ALA A CA  1 
ATOM   7162 C C   . ALA A 1 972  ? 157.923 184.162 199.278 1.00 229.68 ? 990  ALA A C   1 
ATOM   7163 O O   . ALA A 1 972  ? 159.132 183.944 199.429 1.00 228.11 ? 990  ALA A O   1 
ATOM   7164 C CB  . ALA A 1 972  ? 156.366 183.430 201.102 1.00 229.81 ? 990  ALA A CB  1 
ATOM   7165 N N   . PHE A 1 973  ? 157.309 184.004 198.102 1.00 228.45 ? 991  PHE A N   1 
ATOM   7166 C CA  . PHE A 1 973  ? 158.061 183.616 196.912 1.00 226.22 ? 991  PHE A CA  1 
ATOM   7167 C C   . PHE A 1 973  ? 159.139 184.642 196.583 1.00 227.05 ? 991  PHE A C   1 
ATOM   7168 O O   . PHE A 1 973  ? 160.315 184.295 196.412 1.00 225.77 ? 991  PHE A O   1 
ATOM   7169 C CB  . PHE A 1 973  ? 157.111 183.441 195.725 1.00 223.58 ? 991  PHE A CB  1 
ATOM   7170 C CG  . PHE A 1 973  ? 157.521 182.358 194.771 1.00 222.30 ? 991  PHE A CG  1 
ATOM   7171 C CD1 . PHE A 1 973  ? 158.659 182.497 193.996 1.00 222.37 ? 991  PHE A CD1 1 
ATOM   7172 C CD2 . PHE A 1 973  ? 156.762 181.208 194.637 1.00 223.62 ? 991  PHE A CD2 1 
ATOM   7173 C CE1 . PHE A 1 973  ? 159.039 181.507 193.112 1.00 220.99 ? 991  PHE A CE1 1 
ATOM   7174 C CE2 . PHE A 1 973  ? 157.137 180.215 193.752 1.00 223.03 ? 991  PHE A CE2 1 
ATOM   7175 C CZ  . PHE A 1 973  ? 158.277 180.364 192.990 1.00 219.35 ? 991  PHE A CZ  1 
ATOM   7176 N N   . VAL A 1 974  ? 158.762 185.920 196.513 1.00 228.54 ? 992  VAL A N   1 
ATOM   7177 C CA  . VAL A 1 974  ? 159.752 186.938 196.180 1.00 230.48 ? 992  VAL A CA  1 
ATOM   7178 C C   . VAL A 1 974  ? 160.764 187.094 197.309 1.00 231.55 ? 992  VAL A C   1 
ATOM   7179 O O   . VAL A 1 974  ? 161.934 187.401 197.056 1.00 233.16 ? 992  VAL A O   1 
ATOM   7180 C CB  . VAL A 1 974  ? 159.078 188.281 195.824 1.00 236.20 ? 992  VAL A CB  1 
ATOM   7181 C CG1 . VAL A 1 974  ? 158.155 188.103 194.627 1.00 236.91 ? 992  VAL A CG1 1 
ATOM   7182 C CG2 . VAL A 1 974  ? 158.320 188.876 197.003 1.00 239.23 ? 992  VAL A CG2 1 
ATOM   7183 N N   . LEU A 1 975  ? 160.347 186.889 198.564 1.00 229.69 ? 993  LEU A N   1 
ATOM   7184 C CA  . LEU A 1 975  ? 161.289 186.952 199.676 1.00 228.47 ? 993  LEU A CA  1 
ATOM   7185 C C   . LEU A 1 975  ? 162.358 185.878 199.543 1.00 226.41 ? 993  LEU A C   1 
ATOM   7186 O O   . LEU A 1 975  ? 163.552 186.155 199.716 1.00 226.20 ? 993  LEU A O   1 
ATOM   7187 C CB  . LEU A 1 975  ? 160.536 186.808 200.999 1.00 226.84 ? 993  LEU A CB  1 
ATOM   7188 C CG  . LEU A 1 975  ? 161.351 186.780 202.295 1.00 226.74 ? 993  LEU A CG  1 
ATOM   7189 C CD1 . LEU A 1 975  ? 162.136 188.071 202.465 1.00 229.47 ? 993  LEU A CD1 1 
ATOM   7190 C CD2 . LEU A 1 975  ? 160.427 186.556 203.476 1.00 227.61 ? 993  LEU A CD2 1 
ATOM   7191 N N   . ARG A 1 976  ? 161.945 184.651 199.221 1.00 223.98 ? 994  ARG A N   1 
ATOM   7192 C CA  . ARG A 1 976  ? 162.906 183.594 198.934 1.00 223.02 ? 994  ARG A CA  1 
ATOM   7193 C C   . ARG A 1 976  ? 163.787 183.963 197.750 1.00 225.02 ? 994  ARG A C   1 
ATOM   7194 O O   . ARG A 1 976  ? 164.983 183.647 197.740 1.00 222.28 ? 994  ARG A O   1 
ATOM   7195 C CB  . ARG A 1 976  ? 162.165 182.284 198.667 1.00 218.02 ? 994  ARG A CB  1 
ATOM   7196 C CG  . ARG A 1 976  ? 163.048 181.048 198.663 1.00 213.49 ? 994  ARG A CG  1 
ATOM   7197 C CD  . ARG A 1 976  ? 162.239 179.791 198.377 1.00 210.54 ? 994  ARG A CD  1 
ATOM   7198 N NE  . ARG A 1 976  ? 161.233 179.541 199.403 1.00 218.48 ? 994  ARG A NE  1 
ATOM   7199 C CZ  . ARG A 1 976  ? 160.320 178.578 199.358 1.00 219.44 ? 994  ARG A CZ  1 
ATOM   7200 N NH1 . ARG A 1 976  ? 160.234 177.743 198.334 1.00 214.83 ? 994  ARG A NH1 1 
ATOM   7201 N NH2 . ARG A 1 976  ? 159.465 178.450 200.370 1.00 221.28 ? 994  ARG A NH2 1 
ATOM   7202 N N   . CYS A 1 977  ? 163.218 184.646 196.754 1.00 226.85 ? 995  CYS A N   1 
ATOM   7203 C CA  . CYS A 1 977  ? 164.015 185.052 195.601 1.00 227.56 ? 995  CYS A CA  1 
ATOM   7204 C C   . CYS A 1 977  ? 165.125 186.025 195.993 1.00 230.10 ? 995  CYS A C   1 
ATOM   7205 O O   . CYS A 1 977  ? 166.282 185.831 195.601 1.00 231.10 ? 995  CYS A O   1 
ATOM   7206 C CB  . CYS A 1 977  ? 163.119 185.662 194.527 1.00 229.38 ? 995  CYS A CB  1 
ATOM   7207 S SG  . CYS A 1 977  ? 162.202 184.441 193.559 1.00 233.71 ? 995  CYS A SG  1 
ATOM   7208 N N   . PHE A 1 978  ? 164.815 187.070 196.773 1.00 231.90 ? 996  PHE A N   1 
ATOM   7209 C CA  . PHE A 1 978  ? 165.907 187.971 197.158 1.00 234.53 ? 996  PHE A CA  1 
ATOM   7210 C C   . PHE A 1 978  ? 166.853 187.323 198.159 1.00 233.23 ? 996  PHE A C   1 
ATOM   7211 O O   . PHE A 1 978  ? 168.034 187.686 198.194 1.00 236.70 ? 996  PHE A O   1 
ATOM   7212 C CB  . PHE A 1 978  ? 165.489 189.328 197.761 1.00 238.24 ? 996  PHE A CB  1 
ATOM   7213 C CG  . PHE A 1 978  ? 164.141 189.841 197.354 1.00 242.45 ? 996  PHE A CG  1 
ATOM   7214 C CD1 . PHE A 1 978  ? 163.927 190.357 196.087 1.00 245.55 ? 996  PHE A CD1 1 
ATOM   7215 C CD2 . PHE A 1 978  ? 163.089 189.813 198.248 1.00 242.27 ? 996  PHE A CD2 1 
ATOM   7216 C CE1 . PHE A 1 978  ? 162.683 190.834 195.721 1.00 247.20 ? 996  PHE A CE1 1 
ATOM   7217 C CE2 . PHE A 1 978  ? 161.844 190.292 197.891 1.00 244.48 ? 996  PHE A CE2 1 
ATOM   7218 C CZ  . PHE A 1 978  ? 161.640 190.799 196.626 1.00 247.51 ? 996  PHE A CZ  1 
ATOM   7219 N N   . LEU A 1 979  ? 166.371 186.385 198.976 1.00 228.95 ? 997  LEU A N   1 
ATOM   7220 C CA  . LEU A 1 979  ? 167.286 185.645 199.837 1.00 228.17 ? 997  LEU A CA  1 
ATOM   7221 C C   . LEU A 1 979  ? 168.284 184.850 199.006 1.00 228.79 ? 997  LEU A C   1 
ATOM   7222 O O   . LEU A 1 979  ? 169.461 184.743 199.369 1.00 230.71 ? 997  LEU A O   1 
ATOM   7223 C CB  . LEU A 1 979  ? 166.501 184.724 200.772 1.00 226.63 ? 997  LEU A CB  1 
ATOM   7224 C CG  . LEU A 1 979  ? 165.770 185.367 201.957 1.00 226.51 ? 997  LEU A CG  1 
ATOM   7225 C CD1 . LEU A 1 979  ? 164.940 184.327 202.689 1.00 222.47 ? 997  LEU A CD1 1 
ATOM   7226 C CD2 . LEU A 1 979  ? 166.745 186.029 202.924 1.00 231.52 ? 997  LEU A CD2 1 
ATOM   7227 N N   . GLU A 1 980  ? 167.831 184.289 197.884 1.00 226.42 ? 998  GLU A N   1 
ATOM   7228 C CA  . GLU A 1 980  ? 168.751 183.606 196.980 1.00 224.62 ? 998  GLU A CA  1 
ATOM   7229 C C   . GLU A 1 980  ? 169.651 184.595 196.244 1.00 229.77 ? 998  GLU A C   1 
ATOM   7230 O O   . GLU A 1 980  ? 170.788 184.262 195.894 1.00 229.15 ? 998  GLU A O   1 
ATOM   7231 C CB  . GLU A 1 980  ? 167.968 182.759 195.980 1.00 216.10 ? 998  GLU A CB  1 
ATOM   7232 C CG  . GLU A 1 980  ? 168.848 182.029 194.984 1.00 211.17 ? 998  GLU A CG  1 
ATOM   7233 C CD  . GLU A 1 980  ? 168.261 180.704 194.550 1.00 205.28 ? 998  GLU A CD  1 
ATOM   7234 O OE1 . GLU A 1 980  ? 168.076 179.821 195.414 1.00 199.98 ? 998  GLU A OE1 1 
ATOM   7235 O OE2 . GLU A 1 980  ? 167.989 180.545 193.343 1.00 202.83 ? 998  GLU A OE2 1 
ATOM   7236 N N   . ALA A 1 981  ? 169.151 185.804 195.978 1.00 234.12 ? 999  ALA A N   1 
ATOM   7237 C CA  . ALA A 1 981  ? 169.895 186.792 195.202 1.00 233.34 ? 999  ALA A CA  1 
ATOM   7238 C C   . ALA A 1 981  ? 170.894 187.599 196.023 1.00 234.15 ? 999  ALA A C   1 
ATOM   7239 O O   . ALA A 1 981  ? 171.745 188.271 195.428 1.00 231.84 ? 999  ALA A O   1 
ATOM   7240 C CB  . ALA A 1 981  ? 168.922 187.760 194.523 1.00 233.86 ? 999  ALA A CB  1 
ATOM   7241 N N   . ASP A 1 982  ? 170.802 187.571 197.354 1.00 236.55 ? 1000 ASP A N   1 
ATOM   7242 C CA  . ASP A 1 982  ? 171.662 188.384 198.212 1.00 237.96 ? 1000 ASP A CA  1 
ATOM   7243 C C   . ASP A 1 982  ? 173.159 188.159 197.983 1.00 238.32 ? 1000 ASP A C   1 
ATOM   7244 O O   . ASP A 1 982  ? 173.912 189.140 197.952 1.00 240.59 ? 1000 ASP A O   1 
ATOM   7245 C CB  . ASP A 1 982  ? 171.325 188.143 199.687 1.00 238.63 ? 1000 ASP A CB  1 
ATOM   7246 C CG  . ASP A 1 982  ? 171.711 189.314 200.569 1.00 242.38 ? 1000 ASP A CG  1 
ATOM   7247 O OD1 . ASP A 1 982  ? 171.253 190.444 200.297 1.00 244.64 ? 1000 ASP A OD1 1 
ATOM   7248 O OD2 . ASP A 1 982  ? 172.473 189.103 201.536 1.00 239.63 ? 1000 ASP A OD2 1 
ATOM   7249 N N   . PRO A 1 983  ? 173.652 186.921 197.834 1.00 235.44 ? 1001 PRO A N   1 
ATOM   7250 C CA  . PRO A 1 983  ? 175.083 186.756 197.525 1.00 233.61 ? 1001 PRO A CA  1 
ATOM   7251 C C   . PRO A 1 983  ? 175.498 187.320 196.174 1.00 230.50 ? 1001 PRO A C   1 
ATOM   7252 O O   . PRO A 1 983  ? 176.693 187.575 195.978 1.00 229.47 ? 1001 PRO A O   1 
ATOM   7253 C CB  . PRO A 1 983  ? 175.280 185.234 197.566 1.00 230.48 ? 1001 PRO A CB  1 
ATOM   7254 C CG  . PRO A 1 983  ? 174.159 184.730 198.388 1.00 230.41 ? 1001 PRO A CG  1 
ATOM   7255 C CD  . PRO A 1 983  ? 173.014 185.604 198.010 1.00 232.48 ? 1001 PRO A CD  1 
ATOM   7256 N N   . TYR A 1 984  ? 174.562 187.526 195.248 1.00 227.33 ? 1002 TYR A N   1 
ATOM   7257 C CA  . TYR A 1 984  ? 174.877 187.898 193.873 1.00 224.51 ? 1002 TYR A CA  1 
ATOM   7258 C C   . TYR A 1 984  ? 174.792 189.397 193.617 1.00 228.49 ? 1002 TYR A C   1 
ATOM   7259 O O   . TYR A 1 984  ? 175.544 189.917 192.788 1.00 228.27 ? 1002 TYR A O   1 
ATOM   7260 C CB  . TYR A 1 984  ? 173.945 187.150 192.917 1.00 219.33 ? 1002 TYR A CB  1 
ATOM   7261 C CG  . TYR A 1 984  ? 174.194 185.660 192.938 1.00 219.47 ? 1002 TYR A CG  1 
ATOM   7262 C CD1 . TYR A 1 984  ? 175.278 185.112 192.269 1.00 215.35 ? 1002 TYR A CD1 1 
ATOM   7263 C CD2 . TYR A 1 984  ? 173.366 184.807 193.654 1.00 222.42 ? 1002 TYR A CD2 1 
ATOM   7264 C CE1 . TYR A 1 984  ? 175.521 183.754 192.294 1.00 210.17 ? 1002 TYR A CE1 1 
ATOM   7265 C CE2 . TYR A 1 984  ? 173.601 183.446 193.686 1.00 218.44 ? 1002 TYR A CE2 1 
ATOM   7266 C CZ  . TYR A 1 984  ? 174.681 182.926 193.005 1.00 208.77 ? 1002 TYR A CZ  1 
ATOM   7267 O OH  . TYR A 1 984  ? 174.924 181.574 193.031 1.00 202.12 ? 1002 TYR A OH  1 
ATOM   7268 N N   . ILE A 1 985  ? 173.889 190.103 194.296 1.00 231.27 ? 1003 ILE A N   1 
ATOM   7269 C CA  . ILE A 1 985  ? 173.814 191.554 194.250 1.00 233.76 ? 1003 ILE A CA  1 
ATOM   7270 C C   . ILE A 1 985  ? 173.489 192.072 195.649 1.00 238.21 ? 1003 ILE A C   1 
ATOM   7271 O O   . ILE A 1 985  ? 173.155 191.308 196.553 1.00 238.23 ? 1003 ILE A O   1 
ATOM   7272 C CB  . ILE A 1 985  ? 172.787 192.060 193.212 1.00 229.04 ? 1003 ILE A CB  1 
ATOM   7273 C CG1 . ILE A 1 985  ? 171.386 191.476 193.451 1.00 229.94 ? 1003 ILE A CG1 1 
ATOM   7274 C CG2 . ILE A 1 985  ? 173.258 191.740 191.798 1.00 225.54 ? 1003 ILE A CG2 1 
ATOM   7275 C CD1 . ILE A 1 985  ? 170.274 192.399 192.990 1.00 229.05 ? 1003 ILE A CD1 1 
ATOM   7276 N N   . ASP A 1 986  ? 173.579 193.388 195.812 1.00 242.11 ? 1004 ASP A N   1 
ATOM   7277 C CA  . ASP A 1 986  ? 173.207 194.019 197.069 1.00 242.77 ? 1004 ASP A CA  1 
ATOM   7278 C C   . ASP A 1 986  ? 171.696 194.199 197.121 1.00 234.59 ? 1004 ASP A C   1 
ATOM   7279 O O   . ASP A 1 986  ? 171.103 194.804 196.223 1.00 228.83 ? 1004 ASP A O   1 
ATOM   7280 C CB  . ASP A 1 986  ? 173.909 195.368 197.225 1.00 250.44 ? 1004 ASP A CB  1 
ATOM   7281 C CG  . ASP A 1 986  ? 175.383 195.302 196.877 1.00 253.36 ? 1004 ASP A CG  1 
ATOM   7282 O OD1 . ASP A 1 986  ? 176.042 194.312 197.259 1.00 252.63 ? 1004 ASP A OD1 1 
ATOM   7283 O OD2 . ASP A 1 986  ? 175.883 196.243 196.226 1.00 255.81 ? 1004 ASP A OD2 1 
ATOM   7284 N N   . ILE A 1 987  ? 171.081 193.668 198.176 1.00 232.18 ? 1005 ILE A N   1 
ATOM   7285 C CA  . ILE A 1 987  ? 169.645 193.769 198.411 1.00 229.68 ? 1005 ILE A CA  1 
ATOM   7286 C C   . ILE A 1 987  ? 169.435 194.672 199.615 1.00 228.68 ? 1005 ILE A C   1 
ATOM   7287 O O   . ILE A 1 987  ? 170.080 194.491 200.655 1.00 229.65 ? 1005 ILE A O   1 
ATOM   7288 C CB  . ILE A 1 987  ? 169.005 192.388 198.645 1.00 233.71 ? 1005 ILE A CB  1 
ATOM   7289 C CG1 . ILE A 1 987  ? 169.262 191.442 197.459 1.00 233.53 ? 1005 ILE A CG1 1 
ATOM   7290 C CG2 . ILE A 1 987  ? 167.510 192.536 198.933 1.00 233.26 ? 1005 ILE A CG2 1 
ATOM   7291 C CD1 . ILE A 1 987  ? 168.709 191.910 196.113 1.00 229.01 ? 1005 ILE A CD1 1 
ATOM   7292 N N   . ASP A 1 988  ? 168.541 195.645 199.472 1.00 226.18 ? 1006 ASP A N   1 
ATOM   7293 C CA  . ASP A 1 988  ? 168.263 196.566 200.564 1.00 231.68 ? 1006 ASP A CA  1 
ATOM   7294 C C   . ASP A 1 988  ? 167.631 195.814 201.727 1.00 233.86 ? 1006 ASP A C   1 
ATOM   7295 O O   . ASP A 1 988  ? 166.582 195.181 201.576 1.00 232.24 ? 1006 ASP A O   1 
ATOM   7296 C CB  . ASP A 1 988  ? 167.342 197.689 200.090 1.00 235.48 ? 1006 ASP A CB  1 
ATOM   7297 C CG  . ASP A 1 988  ? 167.643 199.013 200.764 1.00 242.03 ? 1006 ASP A CG  1 
ATOM   7298 O OD1 . ASP A 1 988  ? 168.099 199.003 201.927 1.00 246.69 ? 1006 ASP A OD1 1 
ATOM   7299 O OD2 . ASP A 1 988  ? 167.423 200.065 200.129 1.00 242.18 ? 1006 ASP A OD2 1 
ATOM   7300 N N   . GLN A 1 989  ? 168.275 195.883 202.892 1.00 236.51 ? 1007 GLN A N   1 
ATOM   7301 C CA  . GLN A 1 989  ? 167.785 195.162 204.059 1.00 237.83 ? 1007 GLN A CA  1 
ATOM   7302 C C   . GLN A 1 989  ? 166.506 195.763 204.623 1.00 238.18 ? 1007 GLN A C   1 
ATOM   7303 O O   . GLN A 1 989  ? 165.746 195.049 205.284 1.00 237.43 ? 1007 GLN A O   1 
ATOM   7304 C CB  . GLN A 1 989  ? 168.862 195.123 205.147 1.00 237.57 ? 1007 GLN A CB  1 
ATOM   7305 C CG  . GLN A 1 989  ? 169.831 193.958 205.006 1.00 238.41 ? 1007 GLN A CG  1 
ATOM   7306 C CD  . GLN A 1 989  ? 170.708 194.070 203.775 1.00 239.64 ? 1007 GLN A CD  1 
ATOM   7307 O OE1 . GLN A 1 989  ? 170.944 195.164 203.263 1.00 238.04 ? 1007 GLN A OE1 1 
ATOM   7308 N NE2 . GLN A 1 989  ? 171.191 192.932 203.288 1.00 240.83 ? 1007 GLN A NE2 1 
ATOM   7309 N N   . ASN A 1 990  ? 166.255 197.053 204.390 1.00 239.13 ? 1008 ASN A N   1 
ATOM   7310 C CA  . ASN A 1 990  ? 164.973 197.623 204.793 1.00 238.45 ? 1008 ASN A CA  1 
ATOM   7311 C C   . ASN A 1 990  ? 163.818 196.973 204.041 1.00 240.11 ? 1008 ASN A C   1 
ATOM   7312 O O   . ASN A 1 990  ? 162.757 196.740 204.627 1.00 241.40 ? 1008 ASN A O   1 
ATOM   7313 C CB  . ASN A 1 990  ? 164.954 199.143 204.588 1.00 239.94 ? 1008 ASN A CB  1 
ATOM   7314 C CG  . ASN A 1 990  ? 165.394 199.566 203.196 1.00 244.14 ? 1008 ASN A CG  1 
ATOM   7315 O OD1 . ASN A 1 990  ? 164.987 198.979 202.194 1.00 243.94 ? 1008 ASN A OD1 1 
ATOM   7316 N ND2 . ASN A 1 990  ? 166.230 200.596 203.130 1.00 249.87 ? 1008 ASN A ND2 1 
ATOM   7317 N N   . VAL A 1 991  ? 164.006 196.671 202.753 1.00 239.60 ? 1009 VAL A N   1 
ATOM   7318 C CA  . VAL A 1 991  ? 162.985 195.951 201.994 1.00 239.13 ? 1009 VAL A CA  1 
ATOM   7319 C C   . VAL A 1 991  ? 162.737 194.581 202.612 1.00 238.34 ? 1009 VAL A C   1 
ATOM   7320 O O   . VAL A 1 991  ? 161.587 194.146 202.763 1.00 238.30 ? 1009 VAL A O   1 
ATOM   7321 C CB  . VAL A 1 991  ? 163.410 195.839 200.515 1.00 237.09 ? 1009 VAL A CB  1 
ATOM   7322 C CG1 . VAL A 1 991  ? 162.606 194.763 199.772 1.00 235.59 ? 1009 VAL A CG1 1 
ATOM   7323 C CG2 . VAL A 1 991  ? 163.272 197.184 199.820 1.00 237.78 ? 1009 VAL A CG2 1 
ATOM   7324 N N   . LEU A 1 992  ? 163.813 193.876 202.965 1.00 237.15 ? 1010 LEU A N   1 
ATOM   7325 C CA  . LEU A 1 992  ? 163.671 192.544 203.539 1.00 238.34 ? 1010 LEU A CA  1 
ATOM   7326 C C   . LEU A 1 992  ? 162.958 192.599 204.884 1.00 241.03 ? 1010 LEU A C   1 
ATOM   7327 O O   . LEU A 1 992  ? 162.092 191.765 205.168 1.00 241.31 ? 1010 LEU A O   1 
ATOM   7328 C CB  . LEU A 1 992  ? 165.044 191.889 203.686 1.00 237.88 ? 1010 LEU A CB  1 
ATOM   7329 C CG  . LEU A 1 992  ? 165.917 191.815 202.428 1.00 237.55 ? 1010 LEU A CG  1 
ATOM   7330 C CD1 . LEU A 1 992  ? 167.310 191.317 202.776 1.00 238.64 ? 1010 LEU A CD1 1 
ATOM   7331 C CD2 . LEU A 1 992  ? 165.275 190.925 201.376 1.00 237.04 ? 1010 LEU A CD2 1 
ATOM   7332 N N   . HIS A 1 993  ? 163.299 193.583 205.719 1.00 241.53 ? 1011 HIS A N   1 
ATOM   7333 C CA  . HIS A 1 993  ? 162.625 193.721 207.005 1.00 241.61 ? 1011 HIS A CA  1 
ATOM   7334 C C   . HIS A 1 993  ? 161.166 194.121 206.834 1.00 242.19 ? 1011 HIS A C   1 
ATOM   7335 O O   . HIS A 1 993  ? 160.313 193.681 207.611 1.00 242.19 ? 1011 HIS A O   1 
ATOM   7336 C CB  . HIS A 1 993  ? 163.353 194.744 207.875 1.00 241.04 ? 1011 HIS A CB  1 
ATOM   7337 C CG  . HIS A 1 993  ? 162.791 194.863 209.257 1.00 241.30 ? 1011 HIS A CG  1 
ATOM   7338 N ND1 . HIS A 1 993  ? 162.903 193.859 210.194 1.00 239.35 ? 1011 HIS A ND1 1 
ATOM   7339 C CD2 . HIS A 1 993  ? 162.108 195.866 209.859 1.00 240.98 ? 1011 HIS A CD2 1 
ATOM   7340 C CE1 . HIS A 1 993  ? 162.315 194.238 211.315 1.00 236.96 ? 1011 HIS A CE1 1 
ATOM   7341 N NE2 . HIS A 1 993  ? 161.825 195.452 211.138 1.00 238.46 ? 1011 HIS A NE2 1 
ATOM   7342 N N   . ARG A 1 994  ? 160.863 194.958 205.839 1.00 242.35 ? 1012 ARG A N   1 
ATOM   7343 C CA  . ARG A 1 994  ? 159.472 195.296 205.551 1.00 240.79 ? 1012 ARG A CA  1 
ATOM   7344 C C   . ARG A 1 994  ? 158.679 194.058 205.158 1.00 241.04 ? 1012 ARG A C   1 
ATOM   7345 O O   . ARG A 1 994  ? 157.557 193.852 205.639 1.00 239.74 ? 1012 ARG A O   1 
ATOM   7346 C CB  . ARG A 1 994  ? 159.399 196.340 204.432 1.00 239.42 ? 1012 ARG A CB  1 
ATOM   7347 C CG  . ARG A 1 994  ? 159.095 197.762 204.885 1.00 240.44 ? 1012 ARG A CG  1 
ATOM   7348 C CD  . ARG A 1 994  ? 158.513 198.572 203.738 1.00 245.97 ? 1012 ARG A CD  1 
ATOM   7349 N NE  . ARG A 1 994  ? 159.447 198.655 202.617 1.00 247.46 ? 1012 ARG A NE  1 
ATOM   7350 C CZ  . ARG A 1 994  ? 159.117 198.892 201.352 1.00 247.26 ? 1012 ARG A CZ  1 
ATOM   7351 N NH1 . ARG A 1 994  ? 157.859 199.064 200.975 1.00 248.79 ? 1012 ARG A NH1 1 
ATOM   7352 N NH2 . ARG A 1 994  ? 160.079 198.958 200.437 1.00 244.29 ? 1012 ARG A NH2 1 
ATOM   7353 N N   . THR A 1 995  ? 159.247 193.225 204.285 1.00 241.72 ? 1013 THR A N   1 
ATOM   7354 C CA  . THR A 1 995  ? 158.576 191.987 203.900 1.00 241.24 ? 1013 THR A CA  1 
ATOM   7355 C C   . THR A 1 995  ? 158.404 191.064 205.098 1.00 238.43 ? 1013 THR A C   1 
ATOM   7356 O O   . THR A 1 995  ? 157.352 190.435 205.261 1.00 236.43 ? 1013 THR A O   1 
ATOM   7357 C CB  . THR A 1 995  ? 159.366 191.284 202.796 1.00 240.28 ? 1013 THR A CB  1 
ATOM   7358 O OG1 . THR A 1 995  ? 160.743 191.188 203.178 1.00 239.23 ? 1013 THR A OG1 1 
ATOM   7359 C CG2 . THR A 1 995  ? 159.256 192.052 201.488 1.00 241.18 ? 1013 THR A CG2 1 
ATOM   7360 N N   . TYR A 1 996  ? 159.430 190.978 205.948 1.00 238.52 ? 1014 TYR A N   1 
ATOM   7361 C CA  . TYR A 1 996  ? 159.354 190.148 207.144 1.00 236.98 ? 1014 TYR A CA  1 
ATOM   7362 C C   . TYR A 1 996  ? 158.241 190.615 208.073 1.00 236.95 ? 1014 TYR A C   1 
ATOM   7363 O O   . TYR A 1 996  ? 157.457 189.802 208.573 1.00 235.10 ? 1014 TYR A O   1 
ATOM   7364 C CB  . TYR A 1 996  ? 160.707 190.177 207.858 1.00 238.38 ? 1014 TYR A CB  1 
ATOM   7365 C CG  . TYR A 1 996  ? 160.805 189.349 209.121 1.00 239.72 ? 1014 TYR A CG  1 
ATOM   7366 C CD1 . TYR A 1 996  ? 160.250 188.078 209.201 1.00 238.67 ? 1014 TYR A CD1 1 
ATOM   7367 C CD2 . TYR A 1 996  ? 161.473 189.842 210.234 1.00 239.96 ? 1014 TYR A CD2 1 
ATOM   7368 C CE1 . TYR A 1 996  ? 160.350 187.328 210.357 1.00 237.37 ? 1014 TYR A CE1 1 
ATOM   7369 C CE2 . TYR A 1 996  ? 161.578 189.100 211.391 1.00 238.93 ? 1014 TYR A CE2 1 
ATOM   7370 C CZ  . TYR A 1 996  ? 161.016 187.845 211.448 1.00 237.86 ? 1014 TYR A CZ  1 
ATOM   7371 O OH  . TYR A 1 996  ? 161.123 187.108 212.603 1.00 234.51 ? 1014 TYR A OH  1 
ATOM   7372 N N   . THR A 1 997  ? 158.148 191.926 208.301 1.00 238.87 ? 1015 THR A N   1 
ATOM   7373 C CA  . THR A 1 997  ? 157.108 192.458 209.175 1.00 238.03 ? 1015 THR A CA  1 
ATOM   7374 C C   . THR A 1 997  ? 155.722 192.249 208.579 1.00 238.54 ? 1015 THR A C   1 
ATOM   7375 O O   . THR A 1 997  ? 154.780 191.889 209.296 1.00 238.04 ? 1015 THR A O   1 
ATOM   7376 C CB  . THR A 1 997  ? 157.355 193.943 209.436 1.00 236.31 ? 1015 THR A CB  1 
ATOM   7377 O OG1 . THR A 1 997  ? 157.673 194.601 208.204 1.00 239.28 ? 1015 THR A OG1 1 
ATOM   7378 C CG2 . THR A 1 997  ? 158.502 194.130 210.419 1.00 232.30 ? 1015 THR A CG2 1 
ATOM   7379 N N   . TRP A 1 998  ? 155.574 192.469 207.269 1.00 238.11 ? 1016 TRP A N   1 
ATOM   7380 C CA  . TRP A 1 998  ? 154.273 192.274 206.641 1.00 235.90 ? 1016 TRP A CA  1 
ATOM   7381 C C   . TRP A 1 998  ? 153.843 190.816 206.689 1.00 235.39 ? 1016 TRP A C   1 
ATOM   7382 O O   . TRP A 1 998  ? 152.661 190.527 206.907 1.00 234.42 ? 1016 TRP A O   1 
ATOM   7383 C CB  . TRP A 1 998  ? 154.301 192.765 205.195 1.00 235.77 ? 1016 TRP A CB  1 
ATOM   7384 C CG  . TRP A 1 998  ? 152.935 192.886 204.599 1.00 237.32 ? 1016 TRP A CG  1 
ATOM   7385 C CD1 . TRP A 1 998  ? 152.021 193.869 204.840 1.00 236.95 ? 1016 TRP A CD1 1 
ATOM   7386 C CD2 . TRP A 1 998  ? 152.321 191.986 203.669 1.00 238.73 ? 1016 TRP A CD2 1 
ATOM   7387 N NE1 . TRP A 1 998  ? 150.877 193.640 204.115 1.00 238.09 ? 1016 TRP A NE1 1 
ATOM   7388 C CE2 . TRP A 1 998  ? 151.036 192.489 203.389 1.00 240.57 ? 1016 TRP A CE2 1 
ATOM   7389 C CE3 . TRP A 1 998  ? 152.734 190.805 203.046 1.00 237.32 ? 1016 TRP A CE3 1 
ATOM   7390 C CZ2 . TRP A 1 998  ? 150.162 191.854 202.510 1.00 242.78 ? 1016 TRP A CZ2 1 
ATOM   7391 C CZ3 . TRP A 1 998  ? 151.864 190.176 202.175 1.00 239.26 ? 1016 TRP A CZ3 1 
ATOM   7392 C CH2 . TRP A 1 998  ? 150.593 190.701 201.915 1.00 242.24 ? 1016 TRP A CH2 1 
ATOM   7393 N N   . LEU A 1 999  ? 154.778 189.886 206.492 1.00 235.43 ? 1017 LEU A N   1 
ATOM   7394 C CA  . LEU A 1 999  ? 154.443 188.472 206.585 1.00 235.16 ? 1017 LEU A CA  1 
ATOM   7395 C C   . LEU A 1 999  ? 154.152 188.056 208.021 1.00 235.08 ? 1017 LEU A C   1 
ATOM   7396 O O   . LEU A 1 999  ? 153.297 187.193 208.250 1.00 234.12 ? 1017 LEU A O   1 
ATOM   7397 C CB  . LEU A 1 999  ? 155.585 187.628 206.012 1.00 232.92 ? 1017 LEU A CB  1 
ATOM   7398 C CG  . LEU A 1 999  ? 155.761 187.536 204.489 1.00 230.01 ? 1017 LEU A CG  1 
ATOM   7399 C CD1 . LEU A 1 999  ? 156.890 186.574 204.158 1.00 227.75 ? 1017 LEU A CD1 1 
ATOM   7400 C CD2 . LEU A 1 999  ? 154.486 187.101 203.772 1.00 228.96 ? 1017 LEU A CD2 1 
ATOM   7401 N N   . LYS A 1 1000 ? 154.841 188.655 208.994 1.00 235.03 ? 1018 LYS A N   1 
ATOM   7402 C CA  . LYS A 1 1000 ? 154.562 188.364 210.393 1.00 233.42 ? 1018 LYS A CA  1 
ATOM   7403 C C   . LYS A 1 1000 ? 153.215 188.915 210.836 1.00 235.11 ? 1018 LYS A C   1 
ATOM   7404 O O   . LYS A 1 1000 ? 152.594 188.345 211.739 1.00 234.79 ? 1018 LYS A O   1 
ATOM   7405 C CB  . LYS A 1 1000 ? 155.665 188.944 211.280 1.00 230.78 ? 1018 LYS A CB  1 
ATOM   7406 C CG  . LYS A 1 1000 ? 156.893 188.062 211.407 1.00 233.08 ? 1018 LYS A CG  1 
ATOM   7407 C CD  . LYS A 1 1000 ? 156.659 186.901 212.360 1.00 234.33 ? 1018 LYS A CD  1 
ATOM   7408 C CE  . LYS A 1 1000 ? 157.902 186.044 212.480 1.00 234.00 ? 1018 LYS A CE  1 
ATOM   7409 N NZ  . LYS A 1 1000 ? 157.814 185.080 213.604 1.00 234.01 ? 1018 LYS A NZ  1 
ATOM   7410 N N   . GLY A 1 1001 ? 152.755 190.009 210.223 1.00 236.94 ? 1019 GLY A N   1 
ATOM   7411 C CA  . GLY A 1 1001 ? 151.473 190.586 210.590 1.00 238.86 ? 1019 GLY A CA  1 
ATOM   7412 C C   . GLY A 1 1001 ? 150.290 189.664 210.372 1.00 240.54 ? 1019 GLY A C   1 
ATOM   7413 O O   . GLY A 1 1001 ? 149.255 189.843 211.021 1.00 240.62 ? 1019 GLY A O   1 
ATOM   7414 N N   . HIS A 1 1002 ? 150.420 188.683 209.481 1.00 239.67 ? 1020 HIS A N   1 
ATOM   7415 C CA  . HIS A 1 1002 ? 149.362 187.721 209.205 1.00 238.22 ? 1020 HIS A CA  1 
ATOM   7416 C C   . HIS A 1 1002 ? 149.403 186.506 210.128 1.00 238.08 ? 1020 HIS A C   1 
ATOM   7417 O O   . HIS A 1 1002 ? 148.604 185.582 209.947 1.00 236.21 ? 1020 HIS A O   1 
ATOM   7418 C CB  . HIS A 1 1002 ? 149.446 187.265 207.747 1.00 236.59 ? 1020 HIS A CB  1 
ATOM   7419 C CG  . HIS A 1 1002 ? 149.112 188.339 206.761 1.00 237.86 ? 1020 HIS A CG  1 
ATOM   7420 N ND1 . HIS A 1 1002 ? 149.953 189.400 206.503 1.00 238.96 ? 1020 HIS A ND1 1 
ATOM   7421 C CD2 . HIS A 1 1002 ? 148.026 188.519 205.972 1.00 236.93 ? 1020 HIS A CD2 1 
ATOM   7422 C CE1 . HIS A 1 1002 ? 149.401 190.186 205.596 1.00 239.38 ? 1020 HIS A CE1 1 
ATOM   7423 N NE2 . HIS A 1 1002 ? 148.231 189.674 205.257 1.00 237.70 ? 1020 HIS A NE2 1 
ATOM   7424 N N   . GLN A 1 1003 ? 150.306 186.481 211.107 1.00 238.95 ? 1021 GLN A N   1 
ATOM   7425 C CA  . GLN A 1 1003 ? 150.418 185.342 212.006 1.00 236.94 ? 1021 GLN A CA  1 
ATOM   7426 C C   . GLN A 1 1003 ? 149.263 185.338 212.997 1.00 237.67 ? 1021 GLN A C   1 
ATOM   7427 O O   . GLN A 1 1003 ? 148.975 186.356 213.634 1.00 237.50 ? 1021 GLN A O   1 
ATOM   7428 C CB  . GLN A 1 1003 ? 151.754 185.383 212.748 1.00 234.73 ? 1021 GLN A CB  1 
ATOM   7429 C CG  . GLN A 1 1003 ? 152.113 184.087 213.453 1.00 236.41 ? 1021 GLN A CG  1 
ATOM   7430 C CD  . GLN A 1 1003 ? 153.551 184.065 213.932 1.00 238.72 ? 1021 GLN A CD  1 
ATOM   7431 O OE1 . GLN A 1 1003 ? 154.184 185.111 214.078 1.00 237.10 ? 1021 GLN A OE1 1 
ATOM   7432 N NE2 . GLN A 1 1003 ? 154.076 182.870 214.177 1.00 240.83 ? 1021 GLN A NE2 1 
ATOM   7433 N N   . LYS A 1 1004 ? 148.607 184.187 213.125 1.00 237.13 ? 1022 LYS A N   1 
ATOM   7434 C CA  . LYS A 1 1004 ? 147.497 184.016 214.049 1.00 237.69 ? 1022 LYS A CA  1 
ATOM   7435 C C   . LYS A 1 1004 ? 148.030 183.516 215.392 1.00 241.10 ? 1022 LYS A C   1 
ATOM   7436 O O   . LYS A 1 1004 ? 149.230 183.284 215.562 1.00 240.94 ? 1022 LYS A O   1 
ATOM   7437 C CB  . LYS A 1 1004 ? 146.460 183.068 213.450 1.00 234.29 ? 1022 LYS A CB  1 
ATOM   7438 C CG  . LYS A 1 1004 ? 145.752 183.624 212.222 1.00 230.59 ? 1022 LYS A CG  1 
ATOM   7439 C CD  . LYS A 1 1004 ? 144.962 182.548 211.498 1.00 226.33 ? 1022 LYS A CD  1 
ATOM   7440 C CE  . LYS A 1 1004 ? 144.402 183.060 210.182 1.00 223.89 ? 1022 LYS A CE  1 
ATOM   7441 N NZ  . LYS A 1 1004 ? 143.738 181.980 209.401 1.00 222.67 ? 1022 LYS A NZ  1 
ATOM   7442 N N   . SER A 1 1005 ? 147.133 183.350 216.367 1.00 243.72 ? 1023 SER A N   1 
ATOM   7443 C CA  . SER A 1 1005 ? 147.543 182.883 217.687 1.00 245.56 ? 1023 SER A CA  1 
ATOM   7444 C C   . SER A 1 1005 ? 148.100 181.466 217.636 1.00 247.02 ? 1023 SER A C   1 
ATOM   7445 O O   . SER A 1 1005 ? 149.071 181.159 218.337 1.00 246.90 ? 1023 SER A O   1 
ATOM   7446 C CB  . SER A 1 1005 ? 146.362 182.951 218.653 1.00 245.70 ? 1023 SER A CB  1 
ATOM   7447 O OG  . SER A 1 1005 ? 145.230 182.290 218.117 1.00 246.76 ? 1023 SER A OG  1 
ATOM   7448 N N   . ASN A 1 1006 ? 147.507 180.598 216.821 1.00 246.68 ? 1024 ASN A N   1 
ATOM   7449 C CA  . ASN A 1 1006 ? 147.946 179.215 216.698 1.00 243.33 ? 1024 ASN A CA  1 
ATOM   7450 C C   . ASN A 1 1006 ? 149.128 179.042 215.751 1.00 241.03 ? 1024 ASN A C   1 
ATOM   7451 O O   . ASN A 1 1006 ? 149.577 177.908 215.553 1.00 237.44 ? 1024 ASN A O   1 
ATOM   7452 C CB  . ASN A 1 1006 ? 146.786 178.336 216.220 1.00 238.85 ? 1024 ASN A CB  1 
ATOM   7453 C CG  . ASN A 1 1006 ? 146.327 178.686 214.818 1.00 236.70 ? 1024 ASN A CG  1 
ATOM   7454 O OD1 . ASN A 1 1006 ? 146.534 179.804 214.346 1.00 237.67 ? 1024 ASN A OD1 1 
ATOM   7455 N ND2 . ASN A 1 1006 ? 145.702 177.729 214.144 1.00 232.32 ? 1024 ASN A ND2 1 
ATOM   7456 N N   . GLY A 1 1007 ? 149.640 180.124 215.161 1.00 240.78 ? 1025 GLY A N   1 
ATOM   7457 C CA  . GLY A 1 1007 ? 150.726 180.046 214.209 1.00 237.04 ? 1025 GLY A CA  1 
ATOM   7458 C C   . GLY A 1 1007 ? 150.301 179.874 212.767 1.00 232.31 ? 1025 GLY A C   1 
ATOM   7459 O O   . GLY A 1 1007 ? 151.156 179.951 211.875 1.00 229.04 ? 1025 GLY A O   1 
ATOM   7460 N N   . GLU A 1 1008 ? 149.017 179.649 212.505 1.00 232.87 ? 1026 GLU A N   1 
ATOM   7461 C CA  . GLU A 1 1008 ? 148.533 179.555 211.140 1.00 230.58 ? 1026 GLU A CA  1 
ATOM   7462 C C   . GLU A 1 1008 ? 148.529 180.936 210.490 1.00 229.08 ? 1026 GLU A C   1 
ATOM   7463 O O   . GLU A 1 1008 ? 148.562 181.968 211.166 1.00 230.63 ? 1026 GLU A O   1 
ATOM   7464 C CB  . GLU A 1 1008 ? 147.130 178.946 211.110 1.00 232.02 ? 1026 GLU A CB  1 
ATOM   7465 C CG  . GLU A 1 1008 ? 146.821 178.140 209.855 1.00 231.91 ? 1026 GLU A CG  1 
ATOM   7466 C CD  . GLU A 1 1008 ? 145.519 177.364 209.949 1.00 236.16 ? 1026 GLU A CD  1 
ATOM   7467 O OE1 . GLU A 1 1008 ? 145.013 177.162 211.073 1.00 238.11 ? 1026 GLU A OE1 1 
ATOM   7468 O OE2 . GLU A 1 1008 ? 145.000 176.950 208.891 1.00 237.45 ? 1026 GLU A OE2 1 
ATOM   7469 N N   . PHE A 1 1009 ? 148.494 180.940 209.158 1.00 226.38 ? 1027 PHE A N   1 
ATOM   7470 C CA  . PHE A 1 1009 ? 148.553 182.155 208.357 1.00 227.28 ? 1027 PHE A CA  1 
ATOM   7471 C C   . PHE A 1 1009 ? 147.395 182.168 207.367 1.00 228.33 ? 1027 PHE A C   1 
ATOM   7472 O O   . PHE A 1 1009 ? 146.704 181.166 207.167 1.00 225.15 ? 1027 PHE A O   1 
ATOM   7473 C CB  . PHE A 1 1009 ? 149.894 182.271 207.619 1.00 225.09 ? 1027 PHE A CB  1 
ATOM   7474 C CG  . PHE A 1 1009 ? 151.059 182.551 208.525 1.00 225.49 ? 1027 PHE A CG  1 
ATOM   7475 C CD1 . PHE A 1 1009 ? 151.423 183.853 208.824 1.00 228.60 ? 1027 PHE A CD1 1 
ATOM   7476 C CD2 . PHE A 1 1009 ? 151.790 181.514 209.077 1.00 223.46 ? 1027 PHE A CD2 1 
ATOM   7477 C CE1 . PHE A 1 1009 ? 152.494 184.113 209.657 1.00 228.54 ? 1027 PHE A CE1 1 
ATOM   7478 C CE2 . PHE A 1 1009 ? 152.860 181.767 209.910 1.00 225.63 ? 1027 PHE A CE2 1 
ATOM   7479 C CZ  . PHE A 1 1009 ? 153.213 183.069 210.200 1.00 227.68 ? 1027 PHE A CZ  1 
ATOM   7480 N N   . TRP A 1 1010 ? 147.193 183.330 206.747 1.00 231.79 ? 1028 TRP A N   1 
ATOM   7481 C CA  . TRP A 1 1010 ? 146.073 183.557 205.846 1.00 232.94 ? 1028 TRP A CA  1 
ATOM   7482 C C   . TRP A 1 1010 ? 146.512 184.501 204.737 1.00 234.17 ? 1028 TRP A C   1 
ATOM   7483 O O   . TRP A 1 1010 ? 147.289 185.432 204.967 1.00 234.39 ? 1028 TRP A O   1 
ATOM   7484 C CB  . TRP A 1 1010 ? 144.866 184.138 206.592 1.00 232.32 ? 1028 TRP A CB  1 
ATOM   7485 C CG  . TRP A 1 1010 ? 145.112 185.503 207.166 1.00 233.31 ? 1028 TRP A CG  1 
ATOM   7486 C CD1 . TRP A 1 1010 ? 145.922 185.820 208.220 1.00 232.82 ? 1028 TRP A CD1 1 
ATOM   7487 C CD2 . TRP A 1 1010 ? 144.541 186.737 206.718 1.00 234.39 ? 1028 TRP A CD2 1 
ATOM   7488 N NE1 . TRP A 1 1010 ? 145.891 187.172 208.452 1.00 232.98 ? 1028 TRP A NE1 1 
ATOM   7489 C CE2 . TRP A 1 1010 ? 145.050 187.758 207.544 1.00 234.53 ? 1028 TRP A CE2 1 
ATOM   7490 C CE3 . TRP A 1 1010 ? 143.648 187.076 205.698 1.00 232.85 ? 1028 TRP A CE3 1 
ATOM   7491 C CZ2 . TRP A 1 1010 ? 144.696 189.095 207.381 1.00 235.00 ? 1028 TRP A CZ2 1 
ATOM   7492 C CZ3 . TRP A 1 1010 ? 143.297 188.403 205.539 1.00 232.77 ? 1028 TRP A CZ3 1 
ATOM   7493 C CH2 . TRP A 1 1010 ? 143.821 189.396 206.375 1.00 234.61 ? 1028 TRP A CH2 1 
ATOM   7494 N N   . ASP A 1 1011 ? 145.996 184.251 203.533 1.00 234.99 ? 1029 ASP A N   1 
ATOM   7495 C CA  . ASP A 1 1011 ? 146.375 184.993 202.334 1.00 237.56 ? 1029 ASP A CA  1 
ATOM   7496 C C   . ASP A 1 1011 ? 145.249 185.935 201.919 1.00 238.74 ? 1029 ASP A C   1 
ATOM   7497 O O   . ASP A 1 1011 ? 144.197 185.454 201.468 1.00 239.15 ? 1029 ASP A O   1 
ATOM   7498 C CB  . ASP A 1 1011 ? 146.696 184.023 201.195 1.00 239.23 ? 1029 ASP A CB  1 
ATOM   7499 C CG  . ASP A 1 1011 ? 147.364 184.704 200.011 1.00 240.58 ? 1029 ASP A CG  1 
ATOM   7500 O OD1 . ASP A 1 1011 ? 147.926 185.806 200.181 1.00 240.57 ? 1029 ASP A OD1 1 
ATOM   7501 O OD2 . ASP A 1 1011 ? 147.326 184.131 198.902 1.00 243.56 ? 1029 ASP A OD2 1 
ATOM   7502 N N   . PRO A 1 1012 ? 145.392 187.265 202.040 1.00 238.45 ? 1030 PRO A N   1 
ATOM   7503 C CA  . PRO A 1 1012 ? 144.351 188.151 201.496 1.00 239.97 ? 1030 PRO A CA  1 
ATOM   7504 C C   . PRO A 1 1012 ? 144.428 188.345 199.993 1.00 241.40 ? 1030 PRO A C   1 
ATOM   7505 O O   . PRO A 1 1012 ? 143.403 188.673 199.379 1.00 239.62 ? 1030 PRO A O   1 
ATOM   7506 C CB  . PRO A 1 1012 ? 144.600 189.477 202.224 1.00 240.26 ? 1030 PRO A CB  1 
ATOM   7507 C CG  . PRO A 1 1012 ? 146.044 189.469 202.523 1.00 238.18 ? 1030 PRO A CG  1 
ATOM   7508 C CD  . PRO A 1 1012 ? 146.431 188.035 202.752 1.00 235.88 ? 1030 PRO A CD  1 
ATOM   7509 N N   . GLY A 1 1013 ? 145.594 188.153 199.380 1.00 242.90 ? 1031 GLY A N   1 
ATOM   7510 C CA  . GLY A 1 1013 ? 145.776 188.414 197.969 1.00 243.39 ? 1031 GLY A CA  1 
ATOM   7511 C C   . GLY A 1 1013 ? 145.263 187.285 197.097 1.00 242.36 ? 1031 GLY A C   1 
ATOM   7512 O O   . GLY A 1 1013 ? 144.681 186.304 197.563 1.00 240.45 ? 1031 GLY A O   1 
ATOM   7513 N N   . ARG A 1 1014 ? 145.488 187.444 195.794 1.00 244.42 ? 1032 ARG A N   1 
ATOM   7514 C CA  . ARG A 1 1014 ? 145.036 186.496 194.787 1.00 246.74 ? 1032 ARG A CA  1 
ATOM   7515 C C   . ARG A 1 1014 ? 146.059 186.443 193.664 1.00 250.89 ? 1032 ARG A C   1 
ATOM   7516 O O   . ARG A 1 1014 ? 146.522 187.484 193.189 1.00 251.66 ? 1032 ARG A O   1 
ATOM   7517 C CB  . ARG A 1 1014 ? 143.658 186.894 194.241 1.00 242.37 ? 1032 ARG A CB  1 
ATOM   7518 C CG  . ARG A 1 1014 ? 142.934 185.785 193.452 1.00 242.77 ? 1032 ARG A CG  1 
ATOM   7519 C CD  . ARG A 1 1014 ? 143.258 185.694 191.944 1.00 248.05 ? 1032 ARG A CD  1 
ATOM   7520 N NE  . ARG A 1 1014 ? 143.632 186.953 191.302 1.00 249.41 ? 1032 ARG A NE  1 
ATOM   7521 C CZ  . ARG A 1 1014 ? 142.782 187.869 190.853 1.00 248.66 ? 1032 ARG A CZ  1 
ATOM   7522 N NH1 . ARG A 1 1014 ? 141.469 187.724 190.969 1.00 246.36 ? 1032 ARG A NH1 1 
ATOM   7523 N NH2 . ARG A 1 1014 ? 143.261 188.966 190.275 1.00 249.72 ? 1032 ARG A NH2 1 
ATOM   7524 N N   . VAL A 1 1015 ? 146.403 185.229 193.242 1.00 252.82 ? 1033 VAL A N   1 
ATOM   7525 C CA  . VAL A 1 1015 ? 147.422 184.998 192.222 1.00 254.66 ? 1033 VAL A CA  1 
ATOM   7526 C C   . VAL A 1 1015 ? 146.717 184.816 190.886 1.00 255.84 ? 1033 VAL A C   1 
ATOM   7527 O O   . VAL A 1 1015 ? 145.911 183.891 190.721 1.00 252.81 ? 1033 VAL A O   1 
ATOM   7528 C CB  . VAL A 1 1015 ? 148.293 183.778 192.565 1.00 253.56 ? 1033 VAL A CB  1 
ATOM   7529 C CG1 . VAL A 1 1015 ? 149.308 183.508 191.455 1.00 251.62 ? 1033 VAL A CG1 1 
ATOM   7530 C CG2 . VAL A 1 1015 ? 148.993 183.979 193.907 1.00 249.45 ? 1033 VAL A CG2 1 
ATOM   7531 N N   . ILE A 1 1016 ? 147.025 185.694 189.929 1.00 260.16 ? 1034 ILE A N   1 
ATOM   7532 C CA  . ILE A 1 1016 ? 146.347 185.662 188.637 1.00 260.22 ? 1034 ILE A CA  1 
ATOM   7533 C C   . ILE A 1 1016 ? 146.684 184.380 187.885 1.00 261.39 ? 1034 ILE A C   1 
ATOM   7534 O O   . ILE A 1 1016 ? 145.799 183.724 187.322 1.00 259.94 ? 1034 ILE A O   1 
ATOM   7535 C CB  . ILE A 1 1016 ? 146.703 186.913 187.808 1.00 260.52 ? 1034 ILE A CB  1 
ATOM   7536 C CG1 . ILE A 1 1016 ? 146.205 188.196 188.495 1.00 257.95 ? 1034 ILE A CG1 1 
ATOM   7537 C CG2 . ILE A 1 1016 ? 146.122 186.799 186.396 1.00 256.61 ? 1034 ILE A CG2 1 
ATOM   7538 C CD1 . ILE A 1 1016 ? 146.881 189.465 188.002 1.00 256.34 ? 1034 ILE A CD1 1 
ATOM   7539 N N   . HIS A 1 1017 ? 147.960 184.001 187.860 1.00 261.84 ? 1035 HIS A N   1 
ATOM   7540 C CA  . HIS A 1 1017 ? 148.369 182.809 187.129 1.00 256.21 ? 1035 HIS A CA  1 
ATOM   7541 C C   . HIS A 1 1017 ? 147.830 181.557 187.810 1.00 254.36 ? 1035 HIS A C   1 
ATOM   7542 O O   . HIS A 1 1017 ? 147.932 181.406 189.031 1.00 252.73 ? 1035 HIS A O   1 
ATOM   7543 C CB  . HIS A 1 1017 ? 149.892 182.740 187.021 1.00 251.40 ? 1035 HIS A CB  1 
ATOM   7544 C CG  . HIS A 1 1017 ? 150.427 183.276 185.730 1.00 248.99 ? 1035 HIS A CG  1 
ATOM   7545 N ND1 . HIS A 1 1017 ? 150.298 182.601 184.535 1.00 245.31 ? 1035 HIS A ND1 1 
ATOM   7546 C CD2 . HIS A 1 1017 ? 151.085 184.424 185.444 1.00 249.92 ? 1035 HIS A CD2 1 
ATOM   7547 C CE1 . HIS A 1 1017 ? 150.858 183.308 183.570 1.00 243.97 ? 1035 HIS A CE1 1 
ATOM   7548 N NE2 . HIS A 1 1017 ? 151.343 184.419 184.094 1.00 248.55 ? 1035 HIS A NE2 1 
ATOM   7549 N N   . SER A 1 1018 ? 147.255 180.657 187.011 1.00 255.20 ? 1036 SER A N   1 
ATOM   7550 C CA  . SER A 1 1018 ? 146.623 179.465 187.562 1.00 255.27 ? 1036 SER A CA  1 
ATOM   7551 C C   . SER A 1 1018 ? 147.639 178.429 188.027 1.00 252.91 ? 1036 SER A C   1 
ATOM   7552 O O   . SER A 1 1018 ? 147.419 177.778 189.054 1.00 253.38 ? 1036 SER A O   1 
ATOM   7553 C CB  . SER A 1 1018 ? 145.688 178.841 186.525 1.00 254.92 ? 1036 SER A CB  1 
ATOM   7554 O OG  . SER A 1 1018 ? 145.305 177.532 186.909 1.00 254.47 ? 1036 SER A OG  1 
ATOM   7555 N N   . GLU A 1 1019 ? 148.743 178.254 187.297 1.00 250.27 ? 1037 GLU A N   1 
ATOM   7556 C CA  . GLU A 1 1019 ? 149.728 177.251 187.683 1.00 245.43 ? 1037 GLU A CA  1 
ATOM   7557 C C   . GLU A 1 1019 ? 150.437 177.601 188.985 1.00 243.42 ? 1037 GLU A C   1 
ATOM   7558 O O   . GLU A 1 1019 ? 150.932 176.695 189.664 1.00 240.80 ? 1037 GLU A O   1 
ATOM   7559 C CB  . GLU A 1 1019 ? 150.738 177.036 186.542 1.00 240.45 ? 1037 GLU A CB  1 
ATOM   7560 C CG  . GLU A 1 1019 ? 151.907 178.025 186.431 1.00 238.15 ? 1037 GLU A CG  1 
ATOM   7561 C CD  . GLU A 1 1019 ? 151.455 179.452 186.210 1.00 240.45 ? 1037 GLU A CD  1 
ATOM   7562 O OE1 . GLU A 1 1019 ? 150.386 179.652 185.596 1.00 242.37 ? 1037 GLU A OE1 1 
ATOM   7563 O OE2 . GLU A 1 1019 ? 152.177 180.376 186.636 1.00 239.38 ? 1037 GLU A OE2 1 
ATOM   7564 N N   . LEU A 1 1020 ? 150.495 178.885 189.346 1.00 243.43 ? 1038 LEU A N   1 
ATOM   7565 C CA  . LEU A 1 1020 ? 150.968 179.299 190.662 1.00 239.10 ? 1038 LEU A CA  1 
ATOM   7566 C C   . LEU A 1 1020 ? 149.838 179.366 191.679 1.00 241.80 ? 1038 LEU A C   1 
ATOM   7567 O O   . LEU A 1 1020 ? 150.043 179.014 192.846 1.00 235.72 ? 1038 LEU A O   1 
ATOM   7568 C CB  . LEU A 1 1020 ? 151.649 180.671 190.572 1.00 235.00 ? 1038 LEU A CB  1 
ATOM   7569 C CG  . LEU A 1 1020 ? 153.021 180.844 189.895 1.00 229.33 ? 1038 LEU A CG  1 
ATOM   7570 C CD1 . LEU A 1 1020 ? 153.720 182.072 190.460 1.00 224.42 ? 1038 LEU A CD1 1 
ATOM   7571 C CD2 . LEU A 1 1020 ? 153.938 179.629 190.008 1.00 228.22 ? 1038 LEU A CD2 1 
ATOM   7572 N N   . GLN A 1 1021 ? 148.650 179.808 191.259 1.00 247.88 ? 1039 GLN A N   1 
ATOM   7573 C CA  . GLN A 1 1021 ? 147.496 179.804 192.153 1.00 249.14 ? 1039 GLN A CA  1 
ATOM   7574 C C   . GLN A 1 1021 ? 147.074 178.382 192.499 1.00 247.90 ? 1039 GLN A C   1 
ATOM   7575 O O   . GLN A 1 1021 ? 146.643 178.112 193.626 1.00 244.03 ? 1039 GLN A O   1 
ATOM   7576 C CB  . GLN A 1 1021 ? 146.336 180.569 191.508 1.00 248.55 ? 1039 GLN A CB  1 
ATOM   7577 C CG  . GLN A 1 1021 ? 145.112 180.783 192.403 1.00 247.67 ? 1039 GLN A CG  1 
ATOM   7578 C CD  . GLN A 1 1021 ? 145.378 181.740 193.547 1.00 249.02 ? 1039 GLN A CD  1 
ATOM   7579 O OE1 . GLN A 1 1021 ? 145.196 182.950 193.414 1.00 249.96 ? 1039 GLN A OE1 1 
ATOM   7580 N NE2 . GLN A 1 1021 ? 145.811 181.202 194.681 1.00 246.76 ? 1039 GLN A NE2 1 
ATOM   7581 N N   . GLY A 1 1022 ? 147.193 177.460 191.546 1.00 249.21 ? 1040 GLY A N   1 
ATOM   7582 C CA  . GLY A 1 1022 ? 146.710 176.106 191.713 1.00 243.76 ? 1040 GLY A CA  1 
ATOM   7583 C C   . GLY A 1 1022 ? 147.571 175.198 192.559 1.00 240.36 ? 1040 GLY A C   1 
ATOM   7584 O O   . GLY A 1 1022 ? 147.249 174.014 192.693 1.00 236.49 ? 1040 GLY A O   1 
ATOM   7585 N N   . GLY A 1 1023 ? 148.656 175.707 193.136 1.00 240.44 ? 1041 GLY A N   1 
ATOM   7586 C CA  . GLY A 1 1023 ? 149.557 174.876 193.906 1.00 235.70 ? 1041 GLY A CA  1 
ATOM   7587 C C   . GLY A 1 1023 ? 149.100 174.614 195.326 1.00 235.48 ? 1041 GLY A C   1 
ATOM   7588 O O   . GLY A 1 1023 ? 149.711 175.117 196.274 1.00 230.94 ? 1041 GLY A O   1 
ATOM   7589 N N   . ASN A 1 1024 ? 148.041 173.815 195.488 1.00 238.04 ? 1042 ASN A N   1 
ATOM   7590 C CA  . ASN A 1 1024 ? 147.604 173.326 196.797 1.00 236.29 ? 1042 ASN A CA  1 
ATOM   7591 C C   . ASN A 1 1024 ? 147.250 174.490 197.733 1.00 237.12 ? 1042 ASN A C   1 
ATOM   7592 O O   . ASN A 1 1024 ? 147.940 174.801 198.705 1.00 238.68 ? 1042 ASN A O   1 
ATOM   7593 C CB  . ASN A 1 1024 ? 148.670 172.401 197.396 1.00 232.50 ? 1042 ASN A CB  1 
ATOM   7594 C CG  . ASN A 1 1024 ? 148.065 171.234 198.148 1.00 227.77 ? 1042 ASN A CG  1 
ATOM   7595 O OD1 . ASN A 1 1024 ? 147.039 171.374 198.812 1.00 227.74 ? 1042 ASN A OD1 1 
ATOM   7596 N ND2 . ASN A 1 1024 ? 148.695 170.071 198.042 1.00 223.09 ? 1042 ASN A ND2 1 
ATOM   7597 N N   . LYS A 1 1025 ? 146.134 175.139 197.395 1.00 236.73 ? 1043 LYS A N   1 
ATOM   7598 C CA  . LYS A 1 1025 ? 145.727 176.390 198.039 1.00 233.91 ? 1043 LYS A CA  1 
ATOM   7599 C C   . LYS A 1 1025 ? 145.303 176.228 199.502 1.00 233.87 ? 1043 LYS A C   1 
ATOM   7600 O O   . LYS A 1 1025 ? 144.912 177.234 200.106 1.00 232.15 ? 1043 LYS A O   1 
ATOM   7601 C CB  . LYS A 1 1025 ? 144.564 177.058 197.285 1.00 230.81 ? 1043 LYS A CB  1 
ATOM   7602 C CG  . LYS A 1 1025 ? 144.537 176.918 195.757 1.00 232.47 ? 1043 LYS A CG  1 
ATOM   7603 C CD  . LYS A 1 1025 ? 143.497 175.884 195.331 1.00 231.65 ? 1043 LYS A CD  1 
ATOM   7604 C CE  . LYS A 1 1025 ? 143.715 175.403 193.907 1.00 231.74 ? 1043 LYS A CE  1 
ATOM   7605 N NZ  . LYS A 1 1025 ? 142.852 174.236 193.574 1.00 221.22 ? 1043 LYS A NZ  1 
ATOM   7606 N N   . SER A 1 1026 ? 145.347 175.029 200.086 1.00 235.07 ? 1044 SER A N   1 
ATOM   7607 C CA  . SER A 1 1026 ? 144.926 174.860 201.468 1.00 233.27 ? 1044 SER A CA  1 
ATOM   7608 C C   . SER A 1 1026 ? 145.853 175.642 202.405 1.00 232.70 ? 1044 SER A C   1 
ATOM   7609 O O   . SER A 1 1026 ? 147.029 175.846 202.089 1.00 233.41 ? 1044 SER A O   1 
ATOM   7610 C CB  . SER A 1 1026 ? 144.926 173.381 201.850 1.00 231.79 ? 1044 SER A CB  1 
ATOM   7611 O OG  . SER A 1 1026 ? 145.103 173.214 203.246 1.00 229.04 ? 1044 SER A OG  1 
ATOM   7612 N N   . PRO A 1 1027 ? 145.353 176.104 203.563 1.00 230.95 ? 1045 PRO A N   1 
ATOM   7613 C CA  . PRO A 1 1027 ? 146.198 176.950 204.428 1.00 229.43 ? 1045 PRO A CA  1 
ATOM   7614 C C   . PRO A 1 1027 ? 147.421 176.244 204.990 1.00 226.85 ? 1045 PRO A C   1 
ATOM   7615 O O   . PRO A 1 1027 ? 148.383 176.926 205.366 1.00 224.54 ? 1045 PRO A O   1 
ATOM   7616 C CB  . PRO A 1 1027 ? 145.246 177.375 205.557 1.00 228.38 ? 1045 PRO A CB  1 
ATOM   7617 C CG  . PRO A 1 1027 ? 143.881 177.036 205.084 1.00 229.02 ? 1045 PRO A CG  1 
ATOM   7618 C CD  . PRO A 1 1027 ? 144.043 175.857 204.195 1.00 229.38 ? 1045 PRO A CD  1 
ATOM   7619 N N   . VAL A 1 1028 ? 147.418 174.911 205.068 1.00 227.23 ? 1046 VAL A N   1 
ATOM   7620 C CA  . VAL A 1 1028 ? 148.579 174.206 205.607 1.00 225.28 ? 1046 VAL A CA  1 
ATOM   7621 C C   . VAL A 1 1028 ? 149.784 174.418 204.701 1.00 223.44 ? 1046 VAL A C   1 
ATOM   7622 O O   . VAL A 1 1028 ? 150.894 174.704 205.172 1.00 223.58 ? 1046 VAL A O   1 
ATOM   7623 C CB  . VAL A 1 1028 ? 148.266 172.708 205.798 1.00 224.91 ? 1046 VAL A CB  1 
ATOM   7624 C CG1 . VAL A 1 1028 ? 149.407 172.006 206.536 1.00 223.81 ? 1046 VAL A CG1 1 
ATOM   7625 C CG2 . VAL A 1 1028 ? 146.955 172.524 206.565 1.00 226.11 ? 1046 VAL A CG2 1 
ATOM   7626 N N   . THR A 1 1029 ? 149.583 174.298 203.389 1.00 222.86 ? 1047 THR A N   1 
ATOM   7627 C CA  . THR A 1 1029 ? 150.669 174.569 202.461 1.00 223.57 ? 1047 THR A CA  1 
ATOM   7628 C C   . THR A 1 1029 ? 151.077 176.031 202.498 1.00 222.86 ? 1047 THR A C   1 
ATOM   7629 O O   . THR A 1 1029 ? 152.250 176.343 202.289 1.00 222.00 ? 1047 THR A O   1 
ATOM   7630 C CB  . THR A 1 1029 ? 150.266 174.179 201.041 1.00 224.65 ? 1047 THR A CB  1 
ATOM   7631 O OG1 . THR A 1 1029 ? 148.923 174.611 200.792 1.00 231.68 ? 1047 THR A OG1 1 
ATOM   7632 C CG2 . THR A 1 1029 ? 150.342 172.678 200.858 1.00 218.65 ? 1047 THR A CG2 1 
ATOM   7633 N N   . LEU A 1 1030 ? 150.136 176.937 202.769 1.00 223.30 ? 1048 LEU A N   1 
ATOM   7634 C CA  . LEU A 1 1030 ? 150.487 178.348 202.886 1.00 224.42 ? 1048 LEU A CA  1 
ATOM   7635 C C   . LEU A 1 1030 ? 151.425 178.573 204.067 1.00 223.16 ? 1048 LEU A C   1 
ATOM   7636 O O   . LEU A 1 1030 ? 152.452 179.255 203.938 1.00 224.04 ? 1048 LEU A O   1 
ATOM   7637 C CB  . LEU A 1 1030 ? 149.216 179.186 203.034 1.00 226.87 ? 1048 LEU A CB  1 
ATOM   7638 C CG  . LEU A 1 1030 ? 149.351 180.711 203.077 1.00 231.02 ? 1048 LEU A CG  1 
ATOM   7639 C CD1 . LEU A 1 1030 ? 149.881 181.241 201.749 1.00 229.65 ? 1048 LEU A CD1 1 
ATOM   7640 C CD2 . LEU A 1 1030 ? 148.014 181.357 203.431 1.00 232.41 ? 1048 LEU A CD2 1 
ATOM   7641 N N   . THR A 1 1031 ? 151.090 177.990 205.224 1.00 222.36 ? 1049 THR A N   1 
ATOM   7642 C CA  . THR A 1 1031 ? 151.950 178.102 206.400 1.00 221.25 ? 1049 THR A CA  1 
ATOM   7643 C C   . THR A 1 1031 ? 153.321 177.496 206.133 1.00 217.19 ? 1049 THR A C   1 
ATOM   7644 O O   . THR A 1 1031 ? 154.356 178.092 206.472 1.00 215.16 ? 1049 THR A O   1 
ATOM   7645 C CB  . THR A 1 1031 ? 151.301 177.416 207.607 1.00 222.33 ? 1049 THR A CB  1 
ATOM   7646 O OG1 . THR A 1 1031 ? 150.977 176.052 207.297 1.00 222.29 ? 1049 THR A OG1 1 
ATOM   7647 C CG2 . THR A 1 1031 ? 150.034 178.140 208.025 1.00 222.91 ? 1049 THR A CG2 1 
ATOM   7648 N N   . ALA A 1 1032 ? 153.341 176.315 205.507 1.00 215.25 ? 1050 ALA A N   1 
ATOM   7649 C CA  . ALA A 1 1032 ? 154.605 175.663 205.202 1.00 210.19 ? 1050 ALA A CA  1 
ATOM   7650 C C   . ALA A 1 1032 ? 155.440 176.500 204.245 1.00 210.28 ? 1050 ALA A C   1 
ATOM   7651 O O   . ALA A 1 1032 ? 156.660 176.598 204.408 1.00 210.54 ? 1050 ALA A O   1 
ATOM   7652 C CB  . ALA A 1 1032 ? 154.349 174.277 204.618 1.00 209.58 ? 1050 ALA A CB  1 
ATOM   7653 N N   . TYR A 1 1033 ? 154.802 177.130 203.257 1.00 212.03 ? 1051 TYR A N   1 
ATOM   7654 C CA  . TYR A 1 1033 ? 155.541 177.954 202.311 1.00 211.41 ? 1051 TYR A CA  1 
ATOM   7655 C C   . TYR A 1 1033 ? 156.136 179.178 202.991 1.00 214.98 ? 1051 TYR A C   1 
ATOM   7656 O O   . TYR A 1 1033 ? 157.288 179.537 202.720 1.00 215.30 ? 1051 TYR A O   1 
ATOM   7657 C CB  . TYR A 1 1033 ? 154.641 178.377 201.151 1.00 211.34 ? 1051 TYR A CB  1 
ATOM   7658 C CG  . TYR A 1 1033 ? 155.347 178.378 199.816 1.00 210.64 ? 1051 TYR A CG  1 
ATOM   7659 C CD1 . TYR A 1 1033 ? 156.261 179.370 199.493 1.00 213.45 ? 1051 TYR A CD1 1 
ATOM   7660 C CD2 . TYR A 1 1033 ? 155.109 177.378 198.883 1.00 214.03 ? 1051 TYR A CD2 1 
ATOM   7661 C CE1 . TYR A 1 1033 ? 156.911 179.372 198.275 1.00 217.50 ? 1051 TYR A CE1 1 
ATOM   7662 C CE2 . TYR A 1 1033 ? 155.753 177.371 197.664 1.00 216.36 ? 1051 TYR A CE2 1 
ATOM   7663 C CZ  . TYR A 1 1033 ? 156.653 178.370 197.365 1.00 216.40 ? 1051 TYR A CZ  1 
ATOM   7664 O OH  . TYR A 1 1033 ? 157.299 178.364 196.151 1.00 216.81 ? 1051 TYR A OH  1 
ATOM   7665 N N   . ILE A 1 1034 ? 155.378 179.834 203.877 1.00 216.82 ? 1052 ILE A N   1 
ATOM   7666 C CA  . ILE A 1 1034 ? 155.934 181.053 204.473 1.00 218.21 ? 1052 ILE A CA  1 
ATOM   7667 C C   . ILE A 1 1034 ? 157.090 180.671 205.393 1.00 217.17 ? 1052 ILE A C   1 
ATOM   7668 O O   . ILE A 1 1034 ? 158.109 181.368 205.419 1.00 217.57 ? 1052 ILE A O   1 
ATOM   7669 C CB  . ILE A 1 1034 ? 154.904 181.944 205.221 1.00 221.71 ? 1052 ILE A CB  1 
ATOM   7670 C CG1 . ILE A 1 1034 ? 155.614 182.996 206.119 1.00 227.38 ? 1052 ILE A CG1 1 
ATOM   7671 C CG2 . ILE A 1 1034 ? 154.012 181.130 206.174 1.00 221.38 ? 1052 ILE A CG2 1 
ATOM   7672 C CD1 . ILE A 1 1034 ? 154.703 184.027 206.789 1.00 228.64 ? 1052 ILE A CD1 1 
ATOM   7673 N N   . VAL A 1 1035 ? 156.965 179.587 206.168 1.00 214.98 ? 1053 VAL A N   1 
ATOM   7674 C CA  . VAL A 1 1035 ? 158.076 179.240 207.056 1.00 213.46 ? 1053 VAL A CA  1 
ATOM   7675 C C   . VAL A 1 1035 ? 159.286 178.759 206.254 1.00 211.70 ? 1053 VAL A C   1 
ATOM   7676 O O   . VAL A 1 1035 ? 160.435 179.062 206.611 1.00 210.79 ? 1053 VAL A O   1 
ATOM   7677 C CB  . VAL A 1 1035 ? 157.652 178.209 208.125 1.00 212.88 ? 1053 VAL A CB  1 
ATOM   7678 C CG1 . VAL A 1 1035 ? 156.517 178.764 208.980 1.00 217.11 ? 1053 VAL A CG1 1 
ATOM   7679 C CG2 . VAL A 1 1035 ? 157.261 176.878 207.510 1.00 210.05 ? 1053 VAL A CG2 1 
ATOM   7680 N N   . THR A 1 1036 ? 159.067 178.016 205.165 1.00 212.16 ? 1054 THR A N   1 
ATOM   7681 C CA  . THR A 1 1036 ? 160.180 177.575 204.336 1.00 211.76 ? 1054 THR A CA  1 
ATOM   7682 C C   . THR A 1 1036 ? 160.791 178.706 203.521 1.00 212.91 ? 1054 THR A C   1 
ATOM   7683 O O   . THR A 1 1036 ? 161.894 178.535 202.991 1.00 211.27 ? 1054 THR A O   1 
ATOM   7684 C CB  . THR A 1 1036 ? 159.739 176.456 203.393 1.00 211.58 ? 1054 THR A CB  1 
ATOM   7685 O OG1 . THR A 1 1036 ? 158.546 176.845 202.707 1.00 219.80 ? 1054 THR A OG1 1 
ATOM   7686 C CG2 . THR A 1 1036 ? 159.482 175.174 204.173 1.00 199.78 ? 1054 THR A CG2 1 
ATOM   7687 N N   . SER A 1 1037 ? 160.102 179.841 203.396 1.00 214.95 ? 1055 SER A N   1 
ATOM   7688 C CA  . SER A 1 1037 ? 160.722 181.052 202.874 1.00 216.88 ? 1055 SER A CA  1 
ATOM   7689 C C   . SER A 1 1037 ? 161.458 181.834 203.953 1.00 214.58 ? 1055 SER A C   1 
ATOM   7690 O O   . SER A 1 1037 ? 162.502 182.433 203.673 1.00 215.43 ? 1055 SER A O   1 
ATOM   7691 C CB  . SER A 1 1037 ? 159.662 181.949 202.230 1.00 222.93 ? 1055 SER A CB  1 
ATOM   7692 O OG  . SER A 1 1037 ? 159.061 181.306 201.120 1.00 226.60 ? 1055 SER A OG  1 
ATOM   7693 N N   . LEU A 1 1038 ? 160.937 181.834 205.181 1.00 212.63 ? 1056 LEU A N   1 
ATOM   7694 C CA  . LEU A 1 1038 ? 161.529 182.587 206.279 1.00 211.83 ? 1056 LEU A CA  1 
ATOM   7695 C C   . LEU A 1 1038 ? 162.737 181.902 206.902 1.00 210.80 ? 1056 LEU A C   1 
ATOM   7696 O O   . LEU A 1 1038 ? 163.467 182.555 207.655 1.00 212.41 ? 1056 LEU A O   1 
ATOM   7697 C CB  . LEU A 1 1038 ? 160.482 182.832 207.373 1.00 210.79 ? 1056 LEU A CB  1 
ATOM   7698 C CG  . LEU A 1 1038 ? 159.451 183.950 207.186 1.00 216.25 ? 1056 LEU A CG  1 
ATOM   7699 C CD1 . LEU A 1 1038 ? 158.474 183.950 208.349 1.00 218.37 ? 1056 LEU A CD1 1 
ATOM   7700 C CD2 . LEU A 1 1038 ? 160.113 185.316 207.073 1.00 220.82 ? 1056 LEU A CD2 1 
ATOM   7701 N N   . LEU A 1 1039 ? 162.955 180.609 206.632 1.00 210.65 ? 1057 LEU A N   1 
ATOM   7702 C CA  . LEU A 1 1039 ? 164.115 179.931 207.215 1.00 212.54 ? 1057 LEU A CA  1 
ATOM   7703 C C   . LEU A 1 1039 ? 165.431 180.571 206.785 1.00 213.11 ? 1057 LEU A C   1 
ATOM   7704 O O   . LEU A 1 1039 ? 166.416 180.510 207.530 1.00 214.32 ? 1057 LEU A O   1 
ATOM   7705 C CB  . LEU A 1 1039 ? 164.135 178.441 206.852 1.00 214.78 ? 1057 LEU A CB  1 
ATOM   7706 C CG  . LEU A 1 1039 ? 163.737 177.937 205.461 1.00 215.27 ? 1057 LEU A CG  1 
ATOM   7707 C CD1 . LEU A 1 1039 ? 164.630 178.486 204.354 1.00 211.66 ? 1057 LEU A CD1 1 
ATOM   7708 C CD2 . LEU A 1 1039 ? 163.724 176.413 205.424 1.00 205.66 ? 1057 LEU A CD2 1 
ATOM   7709 N N   . GLY A 1 1040 ? 165.474 181.186 205.606 1.00 212.56 ? 1058 GLY A N   1 
ATOM   7710 C CA  . GLY A 1 1040 ? 166.680 181.805 205.105 1.00 214.70 ? 1058 GLY A CA  1 
ATOM   7711 C C   . GLY A 1 1040 ? 166.989 183.167 205.678 1.00 220.77 ? 1058 GLY A C   1 
ATOM   7712 O O   . GLY A 1 1040 ? 168.049 183.725 205.379 1.00 223.43 ? 1058 GLY A O   1 
ATOM   7713 N N   . TYR A 1 1041 ? 166.099 183.725 206.500 1.00 222.30 ? 1059 TYR A N   1 
ATOM   7714 C CA  . TYR A 1 1041 ? 166.353 185.006 207.145 1.00 229.14 ? 1059 TYR A CA  1 
ATOM   7715 C C   . TYR A 1 1041 ? 167.326 184.901 208.313 1.00 230.75 ? 1059 TYR A C   1 
ATOM   7716 O O   . TYR A 1 1041 ? 167.705 185.935 208.873 1.00 235.36 ? 1059 TYR A O   1 
ATOM   7717 C CB  . TYR A 1 1041 ? 165.030 185.615 207.632 1.00 232.59 ? 1059 TYR A CB  1 
ATOM   7718 C CG  . TYR A 1 1041 ? 164.969 187.133 207.626 1.00 242.06 ? 1059 TYR A CG  1 
ATOM   7719 C CD1 . TYR A 1 1041 ? 165.183 187.864 206.462 1.00 243.60 ? 1059 TYR A CD1 1 
ATOM   7720 C CD2 . TYR A 1 1041 ? 164.684 187.835 208.790 1.00 245.66 ? 1059 TYR A CD2 1 
ATOM   7721 C CE1 . TYR A 1 1041 ? 165.125 189.242 206.461 1.00 245.30 ? 1059 TYR A CE1 1 
ATOM   7722 C CE2 . TYR A 1 1041 ? 164.622 189.216 208.797 1.00 248.45 ? 1059 TYR A CE2 1 
ATOM   7723 C CZ  . TYR A 1 1041 ? 164.843 189.914 207.630 1.00 248.01 ? 1059 TYR A CZ  1 
ATOM   7724 O OH  . TYR A 1 1041 ? 164.783 191.288 207.630 1.00 245.99 ? 1059 TYR A OH  1 
ATOM   7725 N N   . ARG A 1 1042 ? 167.740 183.689 208.695 1.00 228.11 ? 1060 ARG A N   1 
ATOM   7726 C CA  . ARG A 1 1042 ? 168.739 183.523 209.743 1.00 230.73 ? 1060 ARG A CA  1 
ATOM   7727 C C   . ARG A 1 1042 ? 170.115 184.043 209.342 1.00 235.00 ? 1060 ARG A C   1 
ATOM   7728 O O   . ARG A 1 1042 ? 170.972 184.198 210.219 1.00 236.59 ? 1060 ARG A O   1 
ATOM   7729 C CB  . ARG A 1 1042 ? 168.843 182.048 210.130 1.00 227.12 ? 1060 ARG A CB  1 
ATOM   7730 C CG  . ARG A 1 1042 ? 167.575 181.485 210.753 1.00 225.70 ? 1060 ARG A CG  1 
ATOM   7731 C CD  . ARG A 1 1042 ? 167.816 180.134 211.413 1.00 224.45 ? 1060 ARG A CD  1 
ATOM   7732 N NE  . ARG A 1 1042 ? 168.605 179.237 210.575 1.00 222.25 ? 1060 ARG A NE  1 
ATOM   7733 C CZ  . ARG A 1 1042 ? 168.146 178.585 209.513 1.00 217.24 ? 1060 ARG A CZ  1 
ATOM   7734 N NH1 . ARG A 1 1042 ? 166.889 178.699 209.112 1.00 213.76 ? 1060 ARG A NH1 1 
ATOM   7735 N NH2 . ARG A 1 1042 ? 168.972 177.797 208.832 1.00 210.39 ? 1060 ARG A NH2 1 
ATOM   7736 N N   . LYS A 1 1043 ? 170.350 184.301 208.052 1.00 235.21 ? 1061 LYS A N   1 
ATOM   7737 C CA  . LYS A 1 1043 ? 171.630 184.855 207.623 1.00 236.88 ? 1061 LYS A CA  1 
ATOM   7738 C C   . LYS A 1 1043 ? 171.877 186.220 208.254 1.00 240.04 ? 1061 LYS A C   1 
ATOM   7739 O O   . LYS A 1 1043 ? 172.989 186.510 208.709 1.00 242.30 ? 1061 LYS A O   1 
ATOM   7740 C CB  . LYS A 1 1043 ? 171.660 184.951 206.094 1.00 230.86 ? 1061 LYS A CB  1 
ATOM   7741 C CG  . LYS A 1 1043 ? 172.966 185.476 205.484 1.00 227.46 ? 1061 LYS A CG  1 
ATOM   7742 C CD  . LYS A 1 1043 ? 172.828 185.683 203.981 1.00 225.15 ? 1061 LYS A CD  1 
ATOM   7743 C CE  . LYS A 1 1043 ? 173.919 186.592 203.434 1.00 223.32 ? 1061 LYS A CE  1 
ATOM   7744 N NZ  . LYS A 1 1043 ? 173.685 186.939 202.007 1.00 226.70 ? 1061 LYS A NZ  1 
ATOM   7745 N N   . TYR A 1 1044 ? 170.849 187.067 208.296 1.00 239.59 ? 1062 TYR A N   1 
ATOM   7746 C CA  . TYR A 1 1044 ? 170.992 188.432 208.790 1.00 241.38 ? 1062 TYR A CA  1 
ATOM   7747 C C   . TYR A 1 1044 ? 170.779 188.511 210.297 1.00 244.03 ? 1062 TYR A C   1 
ATOM   7748 O O   . TYR A 1 1044 ? 171.506 189.230 210.991 1.00 245.65 ? 1062 TYR A O   1 
ATOM   7749 C CB  . TYR A 1 1044 ? 170.016 189.357 208.057 1.00 238.15 ? 1062 TYR A CB  1 
ATOM   7750 C CG  . TYR A 1 1044 ? 169.919 189.070 206.577 1.00 235.72 ? 1062 TYR A CG  1 
ATOM   7751 C CD1 . TYR A 1 1044 ? 171.033 189.179 205.756 1.00 235.77 ? 1062 TYR A CD1 1 
ATOM   7752 C CD2 . TYR A 1 1044 ? 168.719 188.676 206.003 1.00 235.81 ? 1062 TYR A CD2 1 
ATOM   7753 C CE1 . TYR A 1 1044 ? 170.953 188.913 204.404 1.00 234.53 ? 1062 TYR A CE1 1 
ATOM   7754 C CE2 . TYR A 1 1044 ? 168.628 188.408 204.653 1.00 236.63 ? 1062 TYR A CE2 1 
ATOM   7755 C CZ  . TYR A 1 1044 ? 169.748 188.528 203.858 1.00 235.76 ? 1062 TYR A CZ  1 
ATOM   7756 O OH  . TYR A 1 1044 ? 169.663 188.262 202.512 1.00 237.06 ? 1062 TYR A OH  1 
ATOM   7757 N N   . GLN A 1 1045 ? 169.787 187.786 210.818 1.00 243.87 ? 1063 GLN A N   1 
ATOM   7758 C CA  . GLN A 1 1045 ? 169.602 187.667 212.253 1.00 242.42 ? 1063 GLN A CA  1 
ATOM   7759 C C   . GLN A 1 1045 ? 168.816 186.386 212.508 1.00 240.15 ? 1063 GLN A C   1 
ATOM   7760 O O   . GLN A 1 1045 ? 167.858 186.115 211.769 1.00 238.58 ? 1063 GLN A O   1 
ATOM   7761 C CB  . GLN A 1 1045 ? 168.875 188.886 212.850 1.00 244.09 ? 1063 GLN A CB  1 
ATOM   7762 C CG  . GLN A 1 1045 ? 167.382 189.059 212.507 1.00 245.16 ? 1063 GLN A CG  1 
ATOM   7763 C CD  . GLN A 1 1045 ? 167.148 189.430 211.055 1.00 246.29 ? 1063 GLN A CD  1 
ATOM   7764 O OE1 . GLN A 1 1045 ? 167.394 188.628 210.154 1.00 244.93 ? 1063 GLN A OE1 1 
ATOM   7765 N NE2 . GLN A 1 1045 ? 166.674 190.649 210.820 1.00 246.90 ? 1063 GLN A NE2 1 
ATOM   7766 N N   . PRO A 1 1046 ? 169.160 185.590 213.524 1.00 239.26 ? 1064 PRO A N   1 
ATOM   7767 C CA  . PRO A 1 1046 ? 168.453 184.320 213.731 1.00 236.92 ? 1064 PRO A CA  1 
ATOM   7768 C C   . PRO A 1 1046 ? 167.187 184.414 214.570 1.00 236.19 ? 1064 PRO A C   1 
ATOM   7769 O O   . PRO A 1 1046 ? 166.514 183.392 214.742 1.00 232.25 ? 1064 PRO A O   1 
ATOM   7770 C CB  . PRO A 1 1046 ? 169.510 183.478 214.454 1.00 234.31 ? 1064 PRO A CB  1 
ATOM   7771 C CG  . PRO A 1 1046 ? 170.296 184.468 215.255 1.00 234.59 ? 1064 PRO A CG  1 
ATOM   7772 C CD  . PRO A 1 1046 ? 170.109 185.835 214.630 1.00 236.99 ? 1064 PRO A CD  1 
ATOM   7773 N N   . ASN A 1 1047 ? 166.841 185.592 215.090 1.00 238.65 ? 1065 ASN A N   1 
ATOM   7774 C CA  . ASN A 1 1047 ? 165.670 185.730 215.961 1.00 237.91 ? 1065 ASN A CA  1 
ATOM   7775 C C   . ASN A 1 1047 ? 164.422 185.786 215.083 1.00 237.09 ? 1065 ASN A C   1 
ATOM   7776 O O   . ASN A 1 1047 ? 163.940 186.849 214.683 1.00 237.85 ? 1065 ASN A O   1 
ATOM   7777 C CB  . ASN A 1 1047 ? 165.772 186.957 216.869 1.00 239.82 ? 1065 ASN A CB  1 
ATOM   7778 C CG  . ASN A 1 1047 ? 166.133 188.233 216.121 1.00 243.66 ? 1065 ASN A CG  1 
ATOM   7779 O OD1 . ASN A 1 1047 ? 167.243 188.371 215.611 1.00 241.60 ? 1065 ASN A OD1 1 
ATOM   7780 N ND2 . ASN A 1 1047 ? 165.193 189.169 216.054 1.00 247.51 ? 1065 ASN A ND2 1 
ATOM   7781 N N   . ILE A 1 1048 ? 163.902 184.600 214.772 1.00 233.73 ? 1066 ILE A N   1 
ATOM   7782 C CA  . ILE A 1 1048 ? 162.642 184.434 214.054 1.00 230.30 ? 1066 ILE A CA  1 
ATOM   7783 C C   . ILE A 1 1048 ? 161.754 183.547 214.913 1.00 228.42 ? 1066 ILE A C   1 
ATOM   7784 O O   . ILE A 1 1048 ? 162.061 182.367 215.122 1.00 225.45 ? 1066 ILE A O   1 
ATOM   7785 C CB  . ILE A 1 1048 ? 162.853 183.831 212.654 1.00 228.34 ? 1066 ILE A CB  1 
ATOM   7786 C CG1 . ILE A 1 1048 ? 163.740 184.759 211.811 1.00 228.54 ? 1066 ILE A CG1 1 
ATOM   7787 C CG2 . ILE A 1 1048 ? 161.505 183.565 211.963 1.00 225.42 ? 1066 ILE A CG2 1 
ATOM   7788 C CD1 . ILE A 1 1048 ? 165.092 184.169 211.480 1.00 227.67 ? 1066 ILE A CD1 1 
ATOM   7789 N N   . ASP A 1 1049 ? 160.651 184.113 215.402 1.00 230.37 ? 1067 ASP A N   1 
ATOM   7790 C CA  . ASP A 1 1049 ? 159.748 183.412 216.314 1.00 233.36 ? 1067 ASP A CA  1 
ATOM   7791 C C   . ASP A 1 1049 ? 158.675 182.717 215.490 1.00 232.85 ? 1067 ASP A C   1 
ATOM   7792 O O   . ASP A 1 1049 ? 157.613 183.277 215.213 1.00 235.90 ? 1067 ASP A O   1 
ATOM   7793 C CB  . ASP A 1 1049 ? 159.140 184.381 217.319 1.00 240.56 ? 1067 ASP A CB  1 
ATOM   7794 C CG  . ASP A 1 1049 ? 158.190 183.698 218.283 1.00 244.34 ? 1067 ASP A CG  1 
ATOM   7795 O OD1 . ASP A 1 1049 ? 158.470 182.547 218.678 1.00 241.42 ? 1067 ASP A OD1 1 
ATOM   7796 O OD2 . ASP A 1 1049 ? 157.163 184.310 218.643 1.00 250.06 ? 1067 ASP A OD2 1 
ATOM   7797 N N   . VAL A 1 1050 ? 158.966 181.481 215.089 1.00 228.16 ? 1068 VAL A N   1 
ATOM   7798 C CA  . VAL A 1 1050 ? 158.037 180.622 214.366 1.00 227.07 ? 1068 VAL A CA  1 
ATOM   7799 C C   . VAL A 1 1050 ? 157.801 179.310 215.115 1.00 226.04 ? 1068 VAL A C   1 
ATOM   7800 O O   . VAL A 1 1050 ? 157.343 178.335 214.532 1.00 225.37 ? 1068 VAL A O   1 
ATOM   7801 C CB  . VAL A 1 1050 ? 158.527 180.364 212.926 1.00 226.15 ? 1068 VAL A CB  1 
ATOM   7802 C CG1 . VAL A 1 1050 ? 158.363 181.620 212.083 1.00 228.90 ? 1068 VAL A CG1 1 
ATOM   7803 C CG2 . VAL A 1 1050 ? 159.981 179.887 212.909 1.00 222.59 ? 1068 VAL A CG2 1 
ATOM   7804 N N   . GLN A 1 1051 ? 158.102 179.282 216.417 1.00 226.00 ? 1069 GLN A N   1 
ATOM   7805 C CA  . GLN A 1 1051 ? 157.933 178.056 217.186 1.00 224.61 ? 1069 GLN A CA  1 
ATOM   7806 C C   . GLN A 1 1051 ? 156.466 177.674 217.312 1.00 226.29 ? 1069 GLN A C   1 
ATOM   7807 O O   . GLN A 1 1051 ? 156.139 176.483 217.322 1.00 225.23 ? 1069 GLN A O   1 
ATOM   7808 C CB  . GLN A 1 1051 ? 158.565 178.207 218.572 1.00 225.12 ? 1069 GLN A CB  1 
ATOM   7809 C CG  . GLN A 1 1051 ? 160.094 178.150 218.589 1.00 228.66 ? 1069 GLN A CG  1 
ATOM   7810 C CD  . GLN A 1 1051 ? 160.752 179.386 218.000 1.00 229.98 ? 1069 GLN A CD  1 
ATOM   7811 O OE1 . GLN A 1 1051 ? 160.151 180.458 217.944 1.00 231.94 ? 1069 GLN A OE1 1 
ATOM   7812 N NE2 . GLN A 1 1051 ? 161.994 179.238 217.554 1.00 228.15 ? 1069 GLN A NE2 1 
ATOM   7813 N N   . GLU A 1 1052 ? 155.572 178.659 217.419 1.00 230.18 ? 1070 GLU A N   1 
ATOM   7814 C CA  . GLU A 1 1052 ? 154.144 178.350 217.419 1.00 232.86 ? 1070 GLU A CA  1 
ATOM   7815 C C   . GLU A 1 1052 ? 153.713 177.753 216.084 1.00 231.95 ? 1070 GLU A C   1 
ATOM   7816 O O   . GLU A 1 1052 ? 152.939 176.789 216.048 1.00 230.60 ? 1070 GLU A O   1 
ATOM   7817 C CB  . GLU A 1 1052 ? 153.312 179.597 217.748 1.00 235.63 ? 1070 GLU A CB  1 
ATOM   7818 C CG  . GLU A 1 1052 ? 153.667 180.885 216.983 1.00 239.37 ? 1070 GLU A CG  1 
ATOM   7819 C CD  . GLU A 1 1052 ? 154.610 181.810 217.743 1.00 241.00 ? 1070 GLU A CD  1 
ATOM   7820 O OE1 . GLU A 1 1052 ? 155.255 181.362 218.714 1.00 238.18 ? 1070 GLU A OE1 1 
ATOM   7821 O OE2 . GLU A 1 1052 ? 154.706 182.995 217.361 1.00 246.67 ? 1070 GLU A OE2 1 
ATOM   7822 N N   . SER A 1 1053 ? 154.217 178.298 214.975 1.00 232.52 ? 1071 SER A N   1 
ATOM   7823 C CA  . SER A 1 1053 ? 153.897 177.733 213.669 1.00 230.79 ? 1071 SER A CA  1 
ATOM   7824 C C   . SER A 1 1053 ? 154.490 176.340 213.518 1.00 224.96 ? 1071 SER A C   1 
ATOM   7825 O O   . SER A 1 1053 ? 153.856 175.447 212.944 1.00 222.56 ? 1071 SER A O   1 
ATOM   7826 C CB  . SER A 1 1053 ? 154.402 178.656 212.561 1.00 233.10 ? 1071 SER A CB  1 
ATOM   7827 O OG  . SER A 1 1053 ? 153.882 179.965 212.711 1.00 236.46 ? 1071 SER A OG  1 
ATOM   7828 N N   . ILE A 1 1054 ? 155.708 176.137 214.024 1.00 224.21 ? 1072 ILE A N   1 
ATOM   7829 C CA  . ILE A 1 1054 ? 156.326 174.818 213.966 1.00 223.01 ? 1072 ILE A CA  1 
ATOM   7830 C C   . ILE A 1 1054 ? 155.509 173.821 214.776 1.00 223.61 ? 1072 ILE A C   1 
ATOM   7831 O O   . ILE A 1 1054 ? 155.327 172.671 214.365 1.00 222.27 ? 1072 ILE A O   1 
ATOM   7832 C CB  . ILE A 1 1054 ? 157.789 174.900 214.455 1.00 222.69 ? 1072 ILE A CB  1 
ATOM   7833 C CG1 . ILE A 1 1054 ? 158.692 175.565 213.398 1.00 218.79 ? 1072 ILE A CG1 1 
ATOM   7834 C CG2 . ILE A 1 1054 ? 158.337 173.517 214.849 1.00 222.21 ? 1072 ILE A CG2 1 
ATOM   7835 C CD1 . ILE A 1 1054 ? 158.865 174.814 212.065 1.00 211.04 ? 1072 ILE A CD1 1 
ATOM   7836 N N   . HIS A 1 1055 ? 155.007 174.240 215.939 1.00 224.94 ? 1073 HIS A N   1 
ATOM   7837 C CA  . HIS A 1 1055 ? 154.159 173.363 216.737 1.00 224.75 ? 1073 HIS A CA  1 
ATOM   7838 C C   . HIS A 1 1055 ? 152.844 173.063 216.031 1.00 225.11 ? 1073 HIS A C   1 
ATOM   7839 O O   . HIS A 1 1055 ? 152.338 171.940 216.120 1.00 224.50 ? 1073 HIS A O   1 
ATOM   7840 C CB  . HIS A 1 1055 ? 153.893 173.989 218.106 1.00 224.49 ? 1073 HIS A CB  1 
ATOM   7841 C CG  . HIS A 1 1055 ? 154.916 173.634 219.138 1.00 224.40 ? 1073 HIS A CG  1 
ATOM   7842 N ND1 . HIS A 1 1055 ? 155.815 174.549 219.641 1.00 224.47 ? 1073 HIS A ND1 1 
ATOM   7843 C CD2 . HIS A 1 1055 ? 155.184 172.462 219.762 1.00 222.99 ? 1073 HIS A CD2 1 
ATOM   7844 C CE1 . HIS A 1 1055 ? 156.593 173.957 220.530 1.00 221.48 ? 1073 HIS A CE1 1 
ATOM   7845 N NE2 . HIS A 1 1055 ? 156.230 172.690 220.622 1.00 220.46 ? 1073 HIS A NE2 1 
ATOM   7846 N N   . PHE A 1 1056 ? 152.274 174.051 215.338 1.00 225.71 ? 1074 PHE A N   1 
ATOM   7847 C CA  . PHE A 1 1056 ? 151.062 173.805 214.562 1.00 226.58 ? 1074 PHE A CA  1 
ATOM   7848 C C   . PHE A 1 1056 ? 151.312 172.782 213.459 1.00 227.33 ? 1074 PHE A C   1 
ATOM   7849 O O   . PHE A 1 1056 ? 150.505 171.865 213.257 1.00 229.94 ? 1074 PHE A O   1 
ATOM   7850 C CB  . PHE A 1 1056 ? 150.550 175.118 213.972 1.00 227.04 ? 1074 PHE A CB  1 
ATOM   7851 C CG  . PHE A 1 1056 ? 149.629 174.942 212.799 1.00 226.24 ? 1074 PHE A CG  1 
ATOM   7852 C CD1 . PHE A 1 1056 ? 148.376 174.374 212.961 1.00 226.81 ? 1074 PHE A CD1 1 
ATOM   7853 C CD2 . PHE A 1 1056 ? 150.016 175.351 211.535 1.00 226.41 ? 1074 PHE A CD2 1 
ATOM   7854 C CE1 . PHE A 1 1056 ? 147.529 174.214 211.880 1.00 229.82 ? 1074 PHE A CE1 1 
ATOM   7855 C CE2 . PHE A 1 1056 ? 149.173 175.194 210.451 1.00 227.15 ? 1074 PHE A CE2 1 
ATOM   7856 C CZ  . PHE A 1 1056 ? 147.929 174.625 210.624 1.00 229.55 ? 1074 PHE A CZ  1 
ATOM   7857 N N   . LEU A 1 1057 ? 152.429 172.920 212.743 1.00 225.23 ? 1075 LEU A N   1 
ATOM   7858 C CA  . LEU A 1 1057 ? 152.768 171.948 211.710 1.00 224.54 ? 1075 LEU A CA  1 
ATOM   7859 C C   . LEU A 1 1057 ? 153.030 170.571 212.309 1.00 226.43 ? 1075 LEU A C   1 
ATOM   7860 O O   . LEU A 1 1057 ? 152.656 169.555 211.714 1.00 227.03 ? 1075 LEU A O   1 
ATOM   7861 C CB  . LEU A 1 1057 ? 153.990 172.421 210.917 1.00 220.89 ? 1075 LEU A CB  1 
ATOM   7862 C CG  . LEU A 1 1057 ? 153.901 173.710 210.081 1.00 219.15 ? 1075 LEU A CG  1 
ATOM   7863 C CD1 . LEU A 1 1057 ? 155.120 173.829 209.174 1.00 212.86 ? 1075 LEU A CD1 1 
ATOM   7864 C CD2 . LEU A 1 1057 ? 152.617 173.821 209.261 1.00 219.71 ? 1075 LEU A CD2 1 
ATOM   7865 N N   . GLU A 1 1058 ? 153.667 170.519 213.481 1.00 226.37 ? 1076 GLU A N   1 
ATOM   7866 C CA  . GLU A 1 1058 ? 153.900 169.244 214.150 1.00 227.10 ? 1076 GLU A CA  1 
ATOM   7867 C C   . GLU A 1 1058 ? 152.587 168.582 214.545 1.00 230.90 ? 1076 GLU A C   1 
ATOM   7868 O O   . GLU A 1 1058 ? 152.431 167.366 214.402 1.00 231.23 ? 1076 GLU A O   1 
ATOM   7869 C CB  . GLU A 1 1058 ? 154.782 169.452 215.382 1.00 226.73 ? 1076 GLU A CB  1 
ATOM   7870 C CG  . GLU A 1 1058 ? 156.273 169.448 215.087 1.00 223.60 ? 1076 GLU A CG  1 
ATOM   7871 C CD  . GLU A 1 1058 ? 157.115 169.726 216.318 1.00 219.13 ? 1076 GLU A CD  1 
ATOM   7872 O OE1 . GLU A 1 1058 ? 156.587 170.315 217.285 1.00 220.62 ? 1076 GLU A OE1 1 
ATOM   7873 O OE2 . GLU A 1 1058 ? 158.307 169.354 216.320 1.00 209.67 ? 1076 GLU A OE2 1 
ATOM   7874 N N   . SER A 1 1059 ? 151.636 169.367 215.053 1.00 232.80 ? 1077 SER A N   1 
ATOM   7875 C CA  . SER A 1 1059 ? 150.327 168.821 215.395 1.00 234.84 ? 1077 SER A CA  1 
ATOM   7876 C C   . SER A 1 1059 ? 149.603 168.316 214.154 1.00 237.62 ? 1077 SER A C   1 
ATOM   7877 O O   . SER A 1 1059 ? 148.955 167.263 214.191 1.00 238.39 ? 1077 SER A O   1 
ATOM   7878 C CB  . SER A 1 1059 ? 149.489 169.879 216.111 1.00 233.08 ? 1077 SER A CB  1 
ATOM   7879 O OG  . SER A 1 1059 ? 148.160 169.430 216.305 1.00 237.75 ? 1077 SER A OG  1 
ATOM   7880 N N   . GLU A 1 1060 ? 149.698 169.056 213.048 1.00 236.70 ? 1078 GLU A N   1 
ATOM   7881 C CA  . GLU A 1 1060 ? 149.085 168.604 211.803 1.00 236.19 ? 1078 GLU A CA  1 
ATOM   7882 C C   . GLU A 1 1060 ? 149.710 167.299 211.324 1.00 232.91 ? 1078 GLU A C   1 
ATOM   7883 O O   . GLU A 1 1060 ? 149.003 166.401 210.853 1.00 232.48 ? 1078 GLU A O   1 
ATOM   7884 C CB  . GLU A 1 1060 ? 149.212 169.695 210.736 1.00 235.61 ? 1078 GLU A CB  1 
ATOM   7885 C CG  . GLU A 1 1060 ? 148.695 169.320 209.344 1.00 238.58 ? 1078 GLU A CG  1 
ATOM   7886 C CD  . GLU A 1 1060 ? 147.293 168.741 209.359 1.00 242.62 ? 1078 GLU A CD  1 
ATOM   7887 O OE1 . GLU A 1 1060 ? 146.355 169.459 209.765 1.00 246.26 ? 1078 GLU A OE1 1 
ATOM   7888 O OE2 . GLU A 1 1060 ? 147.130 167.568 208.964 1.00 239.15 ? 1078 GLU A OE2 1 
ATOM   7889 N N   . PHE A 1 1061 ? 151.034 167.180 211.434 1.00 230.35 ? 1079 PHE A N   1 
ATOM   7890 C CA  . PHE A 1 1061 ? 151.700 165.931 211.077 1.00 227.61 ? 1079 PHE A CA  1 
ATOM   7891 C C   . PHE A 1 1061 ? 151.263 164.795 211.994 1.00 228.89 ? 1079 PHE A C   1 
ATOM   7892 O O   . PHE A 1 1061 ? 151.081 163.659 211.542 1.00 225.99 ? 1079 PHE A O   1 
ATOM   7893 C CB  . PHE A 1 1061 ? 153.216 166.117 211.130 1.00 222.04 ? 1079 PHE A CB  1 
ATOM   7894 C CG  . PHE A 1 1061 ? 153.981 164.836 211.300 1.00 217.73 ? 1079 PHE A CG  1 
ATOM   7895 C CD1 . PHE A 1 1061 ? 154.002 163.885 210.294 1.00 213.02 ? 1079 PHE A CD1 1 
ATOM   7896 C CD2 . PHE A 1 1061 ? 154.684 164.588 212.466 1.00 217.15 ? 1079 PHE A CD2 1 
ATOM   7897 C CE1 . PHE A 1 1061 ? 154.708 162.707 210.452 1.00 209.72 ? 1079 PHE A CE1 1 
ATOM   7898 C CE2 . PHE A 1 1061 ? 155.391 163.413 212.629 1.00 211.45 ? 1079 PHE A CE2 1 
ATOM   7899 C CZ  . PHE A 1 1061 ? 155.403 162.472 211.620 1.00 209.70 ? 1079 PHE A CZ  1 
ATOM   7900 N N   . SER A 1 1062 ? 151.097 165.084 213.286 1.00 231.86 ? 1080 SER A N   1 
ATOM   7901 C CA  . SER A 1 1062 ? 150.614 164.075 214.221 1.00 231.49 ? 1080 SER A CA  1 
ATOM   7902 C C   . SER A 1 1062 ? 149.207 163.616 213.865 1.00 233.49 ? 1080 SER A C   1 
ATOM   7903 O O   . SER A 1 1062 ? 148.884 162.433 214.022 1.00 233.24 ? 1080 SER A O   1 
ATOM   7904 C CB  . SER A 1 1062 ? 150.643 164.627 215.646 1.00 230.47 ? 1080 SER A CB  1 
ATOM   7905 O OG  . SER A 1 1062 ? 151.953 165.026 216.011 1.00 231.07 ? 1080 SER A OG  1 
ATOM   7906 N N   . ARG A 1 1063 ? 148.360 164.532 213.389 1.00 234.96 ? 1081 ARG A N   1 
ATOM   7907 C CA  . ARG A 1 1063 ? 147.022 164.146 212.956 1.00 233.99 ? 1081 ARG A CA  1 
ATOM   7908 C C   . ARG A 1 1063 ? 147.064 163.200 211.762 1.00 231.87 ? 1081 ARG A C   1 
ATOM   7909 O O   . ARG A 1 1063 ? 146.142 162.396 211.583 1.00 229.87 ? 1081 ARG A O   1 
ATOM   7910 C CB  . ARG A 1 1063 ? 146.204 165.388 212.600 1.00 236.65 ? 1081 ARG A CB  1 
ATOM   7911 C CG  . ARG A 1 1063 ? 145.763 166.221 213.791 1.00 240.17 ? 1081 ARG A CG  1 
ATOM   7912 C CD  . ARG A 1 1063 ? 144.487 166.984 213.478 1.00 245.90 ? 1081 ARG A CD  1 
ATOM   7913 N NE  . ARG A 1 1063 ? 144.208 168.017 214.469 1.00 252.50 ? 1081 ARG A NE  1 
ATOM   7914 C CZ  . ARG A 1 1063 ? 144.779 169.216 214.506 1.00 254.15 ? 1081 ARG A CZ  1 
ATOM   7915 N NH1 . ARG A 1 1063 ? 145.696 169.583 213.622 1.00 252.29 ? 1081 ARG A NH1 1 
ATOM   7916 N NH2 . ARG A 1 1063 ? 144.423 170.072 215.460 1.00 256.12 ? 1081 ARG A NH2 1 
ATOM   7917 N N   . GLY A 1 1064 ? 148.111 163.282 210.941 1.00 230.08 ? 1082 GLY A N   1 
ATOM   7918 C CA  . GLY A 1 1064 ? 148.222 162.473 209.743 1.00 225.48 ? 1082 GLY A CA  1 
ATOM   7919 C C   . GLY A 1 1064 ? 147.742 163.225 208.520 1.00 223.06 ? 1082 GLY A C   1 
ATOM   7920 O O   . GLY A 1 1064 ? 146.588 163.662 208.469 1.00 222.94 ? 1082 GLY A O   1 
ATOM   7921 N N   . ILE A 1 1065 ? 148.621 163.376 207.531 1.00 219.93 ? 1083 ILE A N   1 
ATOM   7922 C CA  . ILE A 1 1065 ? 148.362 164.169 206.333 1.00 213.83 ? 1083 ILE A CA  1 
ATOM   7923 C C   . ILE A 1 1065 ? 148.326 163.228 205.138 1.00 208.08 ? 1083 ILE A C   1 
ATOM   7924 O O   . ILE A 1 1065 ? 149.155 162.317 205.025 1.00 206.28 ? 1083 ILE A O   1 
ATOM   7925 C CB  . ILE A 1 1065 ? 149.415 165.280 206.121 1.00 209.08 ? 1083 ILE A CB  1 
ATOM   7926 C CG1 . ILE A 1 1065 ? 149.587 166.178 207.360 1.00 215.47 ? 1083 ILE A CG1 1 
ATOM   7927 C CG2 . ILE A 1 1065 ? 149.034 166.148 204.937 1.00 202.88 ? 1083 ILE A CG2 1 
ATOM   7928 C CD1 . ILE A 1 1065 ? 151.010 166.636 207.561 1.00 213.53 ? 1083 ILE A CD1 1 
ATOM   7929 N N   . SER A 1 1066 ? 147.362 163.454 204.244 1.00 207.25 ? 1084 SER A N   1 
ATOM   7930 C CA  . SER A 1 1066 ? 147.121 162.563 203.116 1.00 207.36 ? 1084 SER A CA  1 
ATOM   7931 C C   . SER A 1 1066 ? 147.870 162.982 201.855 1.00 207.10 ? 1084 SER A C   1 
ATOM   7932 O O   . SER A 1 1066 ? 148.421 162.127 201.155 1.00 203.08 ? 1084 SER A O   1 
ATOM   7933 C CB  . SER A 1 1066 ? 145.621 162.497 202.819 1.00 208.52 ? 1084 SER A CB  1 
ATOM   7934 O OG  . SER A 1 1066 ? 145.197 163.640 202.096 1.00 205.18 ? 1084 SER A OG  1 
ATOM   7935 N N   . ASP A 1 1067 ? 147.906 164.274 201.550 1.00 208.80 ? 1085 ASP A N   1 
ATOM   7936 C CA  . ASP A 1 1067 ? 148.489 164.732 200.299 1.00 207.63 ? 1085 ASP A CA  1 
ATOM   7937 C C   . ASP A 1 1067 ? 150.015 164.696 200.366 1.00 202.35 ? 1085 ASP A C   1 
ATOM   7938 O O   . ASP A 1 1067 ? 150.631 164.989 201.395 1.00 201.21 ? 1085 ASP A O   1 
ATOM   7939 C CB  . ASP A 1 1067 ? 147.986 166.139 199.972 1.00 211.33 ? 1085 ASP A CB  1 
ATOM   7940 C CG  . ASP A 1 1067 ? 148.783 166.812 198.864 1.00 210.70 ? 1085 ASP A CG  1 
ATOM   7941 O OD1 . ASP A 1 1067 ? 149.874 167.356 199.141 1.00 207.61 ? 1085 ASP A OD1 1 
ATOM   7942 O OD2 . ASP A 1 1067 ? 148.313 166.794 197.707 1.00 212.25 ? 1085 ASP A OD2 1 
ATOM   7943 N N   . ASN A 1 1068 ? 150.624 164.335 199.234 1.00 198.30 ? 1086 ASN A N   1 
ATOM   7944 C CA  . ASN A 1 1068 ? 152.067 164.126 199.178 1.00 193.06 ? 1086 ASN A CA  1 
ATOM   7945 C C   . ASN A 1 1068 ? 152.844 165.438 199.236 1.00 192.16 ? 1086 ASN A C   1 
ATOM   7946 O O   . ASN A 1 1068 ? 153.850 165.530 199.946 1.00 192.27 ? 1086 ASN A O   1 
ATOM   7947 C CB  . ASN A 1 1068 ? 152.433 163.354 197.906 1.00 183.45 ? 1086 ASN A CB  1 
ATOM   7948 C CG  . ASN A 1 1068 ? 152.319 161.834 198.066 1.00 178.86 ? 1086 ASN A CG  1 
ATOM   7949 O OD1 . ASN A 1 1068 ? 153.087 161.093 197.455 1.00 175.80 ? 1086 ASN A OD1 1 
ATOM   7950 N ND2 . ASN A 1 1068 ? 151.353 161.363 198.857 1.00 178.10 ? 1086 ASN A ND2 1 
ATOM   7951 N N   . TYR A 1 1069 ? 152.410 166.456 198.489 1.00 191.17 ? 1087 TYR A N   1 
ATOM   7952 C CA  . TYR A 1 1069 ? 153.152 167.715 198.449 1.00 189.53 ? 1087 TYR A CA  1 
ATOM   7953 C C   . TYR A 1 1069 ? 153.090 168.444 199.783 1.00 191.18 ? 1087 TYR A C   1 
ATOM   7954 O O   . TYR A 1 1069 ? 154.078 169.058 200.211 1.00 188.98 ? 1087 TYR A O   1 
ATOM   7955 C CB  . TYR A 1 1069 ? 152.611 168.601 197.332 1.00 187.92 ? 1087 TYR A CB  1 
ATOM   7956 C CG  . TYR A 1 1069 ? 153.160 170.010 197.322 1.00 188.15 ? 1087 TYR A CG  1 
ATOM   7957 C CD1 . TYR A 1 1069 ? 154.525 170.251 197.370 1.00 188.02 ? 1087 TYR A CD1 1 
ATOM   7958 C CD2 . TYR A 1 1069 ? 152.307 171.101 197.251 1.00 195.14 ? 1087 TYR A CD2 1 
ATOM   7959 C CE1 . TYR A 1 1069 ? 155.023 171.539 197.361 1.00 190.92 ? 1087 TYR A CE1 1 
ATOM   7960 C CE2 . TYR A 1 1069 ? 152.795 172.390 197.239 1.00 198.90 ? 1087 TYR A CE2 1 
ATOM   7961 C CZ  . TYR A 1 1069 ? 154.153 172.604 197.292 1.00 194.71 ? 1087 TYR A CZ  1 
ATOM   7962 O OH  . TYR A 1 1069 ? 154.642 173.890 197.278 1.00 203.24 ? 1087 TYR A OH  1 
ATOM   7963 N N   . THR A 1 1070 ? 151.932 168.405 200.442 1.00 195.66 ? 1088 THR A N   1 
ATOM   7964 C CA  . THR A 1 1070 ? 151.832 168.977 201.779 1.00 196.89 ? 1088 THR A CA  1 
ATOM   7965 C C   . THR A 1 1070 ? 152.786 168.271 202.728 1.00 192.20 ? 1088 THR A C   1 
ATOM   7966 O O   . THR A 1 1070 ? 153.466 168.915 203.533 1.00 186.51 ? 1088 THR A O   1 
ATOM   7967 C CB  . THR A 1 1070 ? 150.394 168.882 202.295 1.00 199.17 ? 1088 THR A CB  1 
ATOM   7968 O OG1 . THR A 1 1070 ? 150.063 167.509 202.527 1.00 199.03 ? 1088 THR A OG1 1 
ATOM   7969 C CG2 . THR A 1 1070 ? 149.388 169.498 201.316 1.00 205.08 ? 1088 THR A CG2 1 
ATOM   7970 N N   . LEU A 1 1071 ? 152.875 166.944 202.619 1.00 191.56 ? 1089 LEU A N   1 
ATOM   7971 C CA  . LEU A 1 1071 ? 153.818 166.189 203.435 1.00 187.45 ? 1089 LEU A CA  1 
ATOM   7972 C C   . LEU A 1 1071 ? 155.258 166.581 203.131 1.00 186.27 ? 1089 LEU A C   1 
ATOM   7973 O O   . LEU A 1 1071 ? 156.088 166.670 204.041 1.00 184.70 ? 1089 LEU A O   1 
ATOM   7974 C CB  . LEU A 1 1071 ? 153.609 164.691 203.212 1.00 188.33 ? 1089 LEU A CB  1 
ATOM   7975 C CG  . LEU A 1 1071 ? 154.541 163.720 203.942 1.00 186.30 ? 1089 LEU A CG  1 
ATOM   7976 C CD1 . LEU A 1 1071 ? 154.570 163.962 205.442 1.00 186.82 ? 1089 LEU A CD1 1 
ATOM   7977 C CD2 . LEU A 1 1071 ? 154.124 162.287 203.648 1.00 184.14 ? 1089 LEU A CD2 1 
ATOM   7978 N N   . ALA A 1 1072 ? 155.578 166.807 201.857 1.00 187.62 ? 1090 ALA A N   1 
ATOM   7979 C CA  . ALA A 1 1072 ? 156.944 167.162 201.486 1.00 184.94 ? 1090 ALA A CA  1 
ATOM   7980 C C   . ALA A 1 1072 ? 157.330 168.517 202.060 1.00 184.31 ? 1090 ALA A C   1 
ATOM   7981 O O   . ALA A 1 1072 ? 158.419 168.680 202.631 1.00 181.31 ? 1090 ALA A O   1 
ATOM   7982 C CB  . ALA A 1 1072 ? 157.083 167.173 199.969 1.00 180.48 ? 1090 ALA A CB  1 
ATOM   7983 N N   . LEU A 1 1073 ? 156.448 169.506 201.905 1.00 187.11 ? 1091 LEU A N   1 
ATOM   7984 C CA  . LEU A 1 1073 ? 156.718 170.818 202.481 1.00 190.55 ? 1091 LEU A CA  1 
ATOM   7985 C C   . LEU A 1 1073 ? 156.800 170.745 203.998 1.00 189.97 ? 1091 LEU A C   1 
ATOM   7986 O O   . LEU A 1 1073 ? 157.639 171.424 204.603 1.00 190.70 ? 1091 LEU A O   1 
ATOM   7987 C CB  . LEU A 1 1073 ? 155.647 171.827 202.064 1.00 192.45 ? 1091 LEU A CB  1 
ATOM   7988 C CG  . LEU A 1 1073 ? 156.045 172.841 200.988 1.00 190.29 ? 1091 LEU A CG  1 
ATOM   7989 C CD1 . LEU A 1 1073 ? 154.816 173.572 200.475 1.00 201.88 ? 1091 LEU A CD1 1 
ATOM   7990 C CD2 . LEU A 1 1073 ? 157.075 173.836 201.513 1.00 195.47 ? 1091 LEU A CD2 1 
ATOM   7991 N N   . ILE A 1 1074 ? 155.952 169.923 204.621 1.00 186.58 ? 1092 ILE A N   1 
ATOM   7992 C CA  . ILE A 1 1074 ? 156.015 169.726 206.066 1.00 186.92 ? 1092 ILE A CA  1 
ATOM   7993 C C   . ILE A 1 1074 ? 157.382 169.181 206.457 1.00 186.25 ? 1092 ILE A C   1 
ATOM   7994 O O   . ILE A 1 1074 ? 158.021 169.675 207.391 1.00 183.38 ? 1092 ILE A O   1 
ATOM   7995 C CB  . ILE A 1 1074 ? 154.876 168.786 206.516 1.00 187.83 ? 1092 ILE A CB  1 
ATOM   7996 C CG1 . ILE A 1 1074 ? 153.534 169.535 206.601 1.00 187.73 ? 1092 ILE A CG1 1 
ATOM   7997 C CG2 . ILE A 1 1074 ? 155.188 168.085 207.854 1.00 195.09 ? 1092 ILE A CG2 1 
ATOM   7998 C CD1 . ILE A 1 1074 ? 153.391 170.564 207.719 1.00 199.37 ? 1092 ILE A CD1 1 
ATOM   7999 N N   . THR A 1 1075 ? 157.843 168.148 205.751 1.00 185.76 ? 1093 THR A N   1 
ATOM   8000 C CA  . THR A 1 1075 ? 159.113 167.522 206.096 1.00 183.26 ? 1093 THR A CA  1 
ATOM   8001 C C   . THR A 1 1075 ? 160.264 168.502 205.945 1.00 178.50 ? 1093 THR A C   1 
ATOM   8002 O O   . THR A 1 1075 ? 161.141 168.569 206.811 1.00 178.59 ? 1093 THR A O   1 
ATOM   8003 C CB  . THR A 1 1075 ? 159.350 166.291 205.225 1.00 184.47 ? 1093 THR A CB  1 
ATOM   8004 O OG1 . THR A 1 1075 ? 158.961 166.577 203.877 1.00 186.32 ? 1093 THR A OG1 1 
ATOM   8005 C CG2 . THR A 1 1075 ? 158.550 165.111 205.746 1.00 185.12 ? 1093 THR A CG2 1 
ATOM   8006 N N   . TYR A 1 1076 ? 160.261 169.292 204.869 1.00 177.23 ? 1094 TYR A N   1 
ATOM   8007 C CA  . TYR A 1 1076 ? 161.308 170.295 204.705 1.00 173.25 ? 1094 TYR A CA  1 
ATOM   8008 C C   . TYR A 1 1076 ? 161.251 171.336 205.818 1.00 172.94 ? 1094 TYR A C   1 
ATOM   8009 O O   . TYR A 1 1076 ? 162.294 171.749 206.342 1.00 171.59 ? 1094 TYR A O   1 
ATOM   8010 C CB  . TYR A 1 1076 ? 161.187 170.962 203.333 1.00 172.85 ? 1094 TYR A CB  1 
ATOM   8011 C CG  . TYR A 1 1076 ? 162.295 171.944 202.995 1.00 165.90 ? 1094 TYR A CG  1 
ATOM   8012 C CD1 . TYR A 1 1076 ? 163.631 171.629 203.213 1.00 158.43 ? 1094 TYR A CD1 1 
ATOM   8013 C CD2 . TYR A 1 1076 ? 162.001 173.182 202.445 1.00 167.64 ? 1094 TYR A CD2 1 
ATOM   8014 C CE1 . TYR A 1 1076 ? 164.636 172.521 202.903 1.00 158.03 ? 1094 TYR A CE1 1 
ATOM   8015 C CE2 . TYR A 1 1076 ? 163.001 174.080 202.130 1.00 167.03 ? 1094 TYR A CE2 1 
ATOM   8016 C CZ  . TYR A 1 1076 ? 164.316 173.744 202.360 1.00 162.62 ? 1094 TYR A CZ  1 
ATOM   8017 O OH  . TYR A 1 1076 ? 165.314 174.637 202.047 1.00 167.40 ? 1094 TYR A OH  1 
ATOM   8018 N N   . ALA A 1 1077 ? 160.043 171.755 206.204 1.00 175.31 ? 1095 ALA A N   1 
ATOM   8019 C CA  . ALA A 1 1077 ? 159.902 172.769 207.243 1.00 177.70 ? 1095 ALA A CA  1 
ATOM   8020 C C   . ALA A 1 1077 ? 160.442 172.277 208.581 1.00 176.72 ? 1095 ALA A C   1 
ATOM   8021 O O   . ALA A 1 1077 ? 161.275 172.944 209.206 1.00 173.25 ? 1095 ALA A O   1 
ATOM   8022 C CB  . ALA A 1 1077 ? 158.435 173.177 207.374 1.00 183.50 ? 1095 ALA A CB  1 
ATOM   8023 N N   . LEU A 1 1078 ? 159.990 171.106 209.038 1.00 178.42 ? 1096 LEU A N   1 
ATOM   8024 C CA  . LEU A 1 1078 ? 160.481 170.596 210.317 1.00 180.06 ? 1096 LEU A CA  1 
ATOM   8025 C C   . LEU A 1 1078 ? 161.932 170.133 210.262 1.00 176.84 ? 1096 LEU A C   1 
ATOM   8026 O O   . LEU A 1 1078 ? 162.596 170.125 211.304 1.00 177.20 ? 1096 LEU A O   1 
ATOM   8027 C CB  . LEU A 1 1078 ? 159.610 169.451 210.856 1.00 185.71 ? 1096 LEU A CB  1 
ATOM   8028 C CG  . LEU A 1 1078 ? 158.092 169.425 210.672 1.00 192.23 ? 1096 LEU A CG  1 
ATOM   8029 C CD1 . LEU A 1 1078 ? 157.518 168.105 211.163 1.00 195.47 ? 1096 LEU A CD1 1 
ATOM   8030 C CD2 . LEU A 1 1078 ? 157.440 170.591 211.393 1.00 205.44 ? 1096 LEU A CD2 1 
ATOM   8031 N N   . SER A 1 1079 ? 162.450 169.757 209.089 1.00 173.88 ? 1097 SER A N   1 
ATOM   8032 C CA  . SER A 1 1079 ? 163.855 169.380 208.998 1.00 167.89 ? 1097 SER A CA  1 
ATOM   8033 C C   . SER A 1 1079 ? 164.769 170.595 209.019 1.00 164.88 ? 1097 SER A C   1 
ATOM   8034 O O   . SER A 1 1079 ? 165.889 170.510 209.535 1.00 162.46 ? 1097 SER A O   1 
ATOM   8035 C CB  . SER A 1 1079 ? 164.103 168.568 207.726 1.00 168.66 ? 1097 SER A CB  1 
ATOM   8036 O OG  . SER A 1 1079 ? 163.231 167.454 207.649 1.00 176.52 ? 1097 SER A OG  1 
ATOM   8037 N N   . SER A 1 1080 ? 164.319 171.722 208.462 1.00 167.57 ? 1098 SER A N   1 
ATOM   8038 C CA  . SER A 1 1080 ? 165.143 172.926 208.471 1.00 169.33 ? 1098 SER A CA  1 
ATOM   8039 C C   . SER A 1 1080 ? 165.398 173.412 209.893 1.00 172.40 ? 1098 SER A C   1 
ATOM   8040 O O   . SER A 1 1080 ? 166.519 173.816 210.223 1.00 170.07 ? 1098 SER A O   1 
ATOM   8041 C CB  . SER A 1 1080 ? 164.475 174.020 207.642 1.00 173.30 ? 1098 SER A CB  1 
ATOM   8042 O OG  . SER A 1 1080 ? 164.194 173.563 206.331 1.00 174.66 ? 1098 SER A OG  1 
ATOM   8043 N N   . VAL A 1 1081 ? 164.372 173.374 210.751 1.00 174.93 ? 1099 VAL A N   1 
ATOM   8044 C CA  . VAL A 1 1081 ? 164.516 173.818 212.136 1.00 175.31 ? 1099 VAL A CA  1 
ATOM   8045 C C   . VAL A 1 1081 ? 165.073 172.734 213.051 1.00 176.03 ? 1099 VAL A C   1 
ATOM   8046 O O   . VAL A 1 1081 ? 165.245 172.983 214.252 1.00 173.85 ? 1099 VAL A O   1 
ATOM   8047 C CB  . VAL A 1 1081 ? 163.174 174.329 212.710 1.00 177.36 ? 1099 VAL A CB  1 
ATOM   8048 C CG1 . VAL A 1 1081 ? 162.702 175.552 211.938 1.00 178.22 ? 1099 VAL A CG1 1 
ATOM   8049 C CG2 . VAL A 1 1081 ? 162.085 173.238 212.721 1.00 180.40 ? 1099 VAL A CG2 1 
ATOM   8050 N N   . GLY A 1 1082 ? 165.360 171.544 212.531 1.00 179.95 ? 1100 GLY A N   1 
ATOM   8051 C CA  . GLY A 1 1082 ? 165.894 170.478 213.361 1.00 183.03 ? 1100 GLY A CA  1 
ATOM   8052 C C   . GLY A 1 1082 ? 164.927 169.961 214.403 1.00 186.29 ? 1100 GLY A C   1 
ATOM   8053 O O   . GLY A 1 1082 ? 165.340 169.658 215.529 1.00 187.46 ? 1100 GLY A O   1 
ATOM   8054 N N   . SER A 1 1083 ? 163.649 169.850 214.058 1.00 185.18 ? 1101 SER A N   1 
ATOM   8055 C CA  . SER A 1 1083 ? 162.677 169.317 215.000 1.00 187.13 ? 1101 SER A CA  1 
ATOM   8056 C C   . SER A 1 1083 ? 162.883 167.809 215.160 1.00 192.33 ? 1101 SER A C   1 
ATOM   8057 O O   . SER A 1 1083 ? 163.300 167.141 214.208 1.00 192.66 ? 1101 SER A O   1 
ATOM   8058 C CB  . SER A 1 1083 ? 161.256 169.599 214.522 1.00 186.56 ? 1101 SER A CB  1 
ATOM   8059 O OG  . SER A 1 1083 ? 160.351 168.621 215.005 1.00 189.09 ? 1101 SER A OG  1 
ATOM   8060 N N   . PRO A 1 1084 ? 162.607 167.235 216.341 1.00 194.91 ? 1102 PRO A N   1 
ATOM   8061 C CA  . PRO A 1 1084 ? 162.774 165.778 216.481 1.00 195.53 ? 1102 PRO A CA  1 
ATOM   8062 C C   . PRO A 1 1084 ? 161.815 164.968 215.628 1.00 191.52 ? 1102 PRO A C   1 
ATOM   8063 O O   . PRO A 1 1084 ? 162.153 163.839 215.253 1.00 189.73 ? 1102 PRO A O   1 
ATOM   8064 C CB  . PRO A 1 1084 ? 162.526 165.527 217.977 1.00 194.48 ? 1102 PRO A CB  1 
ATOM   8065 C CG  . PRO A 1 1084 ? 162.577 166.860 218.624 1.00 191.72 ? 1102 PRO A CG  1 
ATOM   8066 C CD  . PRO A 1 1084 ? 162.106 167.825 217.597 1.00 191.01 ? 1102 PRO A CD  1 
ATOM   8067 N N   . LYS A 1 1085 ? 160.634 165.500 215.308 1.00 188.40 ? 1103 LYS A N   1 
ATOM   8068 C CA  . LYS A 1 1085 ? 159.664 164.745 214.525 1.00 186.15 ? 1103 LYS A CA  1 
ATOM   8069 C C   . LYS A 1 1085 ? 160.027 164.675 213.047 1.00 185.30 ? 1103 LYS A C   1 
ATOM   8070 O O   . LYS A 1 1085 ? 159.428 163.877 212.317 1.00 185.78 ? 1103 LYS A O   1 
ATOM   8071 C CB  . LYS A 1 1085 ? 158.257 165.348 214.652 1.00 189.89 ? 1103 LYS A CB  1 
ATOM   8072 C CG  . LYS A 1 1085 ? 157.840 165.866 216.035 1.00 196.50 ? 1103 LYS A CG  1 
ATOM   8073 C CD  . LYS A 1 1085 ? 157.780 164.770 217.092 1.00 201.29 ? 1103 LYS A CD  1 
ATOM   8074 C CE  . LYS A 1 1085 ? 157.813 165.365 218.491 1.00 203.47 ? 1103 LYS A CE  1 
ATOM   8075 N NZ  . LYS A 1 1085 ? 159.177 165.804 218.892 1.00 198.91 ? 1103 LYS A NZ  1 
ATOM   8076 N N   . ALA A 1 1086 ? 160.983 165.489 212.591 1.00 182.93 ? 1104 ALA A N   1 
ATOM   8077 C CA  . ALA A 1 1086 ? 161.289 165.547 211.166 1.00 178.53 ? 1104 ALA A CA  1 
ATOM   8078 C C   . ALA A 1 1086 ? 161.863 164.229 210.664 1.00 177.25 ? 1104 ALA A C   1 
ATOM   8079 O O   . ALA A 1 1086 ? 161.606 163.829 209.524 1.00 174.78 ? 1104 ALA A O   1 
ATOM   8080 C CB  . ALA A 1 1086 ? 162.260 166.693 210.889 1.00 177.26 ? 1104 ALA A CB  1 
ATOM   8081 N N   . LYS A 1 1087 ? 162.657 163.548 211.493 1.00 179.80 ? 1105 LYS A N   1 
ATOM   8082 C CA  . LYS A 1 1087 ? 163.208 162.256 211.097 1.00 183.38 ? 1105 LYS A CA  1 
ATOM   8083 C C   . LYS A 1 1087 ? 162.088 161.246 210.869 1.00 187.08 ? 1105 LYS A C   1 
ATOM   8084 O O   . LYS A 1 1087 ? 162.066 160.538 209.856 1.00 187.60 ? 1105 LYS A O   1 
ATOM   8085 C CB  . LYS A 1 1087 ? 164.199 161.774 212.168 1.00 178.35 ? 1105 LYS A CB  1 
ATOM   8086 C CG  . LYS A 1 1087 ? 164.750 160.337 212.033 1.00 180.05 ? 1105 LYS A CG  1 
ATOM   8087 C CD  . LYS A 1 1087 ? 165.855 160.256 210.987 1.00 177.18 ? 1105 LYS A CD  1 
ATOM   8088 C CE  . LYS A 1 1087 ? 166.553 158.902 211.006 1.00 169.07 ? 1105 LYS A CE  1 
ATOM   8089 N NZ  . LYS A 1 1087 ? 167.895 158.956 210.362 1.00 159.24 ? 1105 LYS A NZ  1 
ATOM   8090 N N   . GLU A 1 1088 ? 161.135 161.179 211.801 1.00 190.35 ? 1106 GLU A N   1 
ATOM   8091 C CA  . GLU A 1 1088 ? 160.015 160.257 211.647 1.00 192.39 ? 1106 GLU A CA  1 
ATOM   8092 C C   . GLU A 1 1088 ? 159.157 160.640 210.447 1.00 187.45 ? 1106 GLU A C   1 
ATOM   8093 O O   . GLU A 1 1088 ? 158.660 159.767 209.723 1.00 187.40 ? 1106 GLU A O   1 
ATOM   8094 C CB  . GLU A 1 1088 ? 159.181 160.238 212.930 1.00 199.84 ? 1106 GLU A CB  1 
ATOM   8095 C CG  . GLU A 1 1088 ? 158.113 159.143 212.992 1.00 204.20 ? 1106 GLU A CG  1 
ATOM   8096 C CD  . GLU A 1 1088 ? 157.082 159.390 214.077 1.00 203.87 ? 1106 GLU A CD  1 
ATOM   8097 O OE1 . GLU A 1 1088 ? 157.284 160.306 214.902 1.00 201.97 ? 1106 GLU A OE1 1 
ATOM   8098 O OE2 . GLU A 1 1088 ? 156.065 158.664 214.105 1.00 205.60 ? 1106 GLU A OE2 1 
ATOM   8099 N N   . ALA A 1 1089 ? 158.956 161.943 210.235 1.00 184.03 ? 1107 ALA A N   1 
ATOM   8100 C CA  . ALA A 1 1089 ? 158.174 162.396 209.090 1.00 185.66 ? 1107 ALA A CA  1 
ATOM   8101 C C   . ALA A 1 1089 ? 158.838 161.995 207.781 1.00 180.82 ? 1107 ALA A C   1 
ATOM   8102 O O   . ALA A 1 1089 ? 158.168 161.536 206.852 1.00 180.79 ? 1107 ALA A O   1 
ATOM   8103 C CB  . ALA A 1 1089 ? 157.981 163.909 209.155 1.00 188.40 ? 1107 ALA A CB  1 
ATOM   8104 N N   . LEU A 1 1090 ? 160.158 162.150 207.690 1.00 176.79 ? 1108 LEU A N   1 
ATOM   8105 C CA  . LEU A 1 1090 ? 160.867 161.680 206.507 1.00 175.21 ? 1108 LEU A CA  1 
ATOM   8106 C C   . LEU A 1 1090 ? 160.769 160.166 206.373 1.00 179.81 ? 1108 LEU A C   1 
ATOM   8107 O O   . LEU A 1 1090 ? 160.696 159.647 205.252 1.00 176.41 ? 1108 LEU A O   1 
ATOM   8108 C CB  . LEU A 1 1090 ? 162.331 162.121 206.568 1.00 171.29 ? 1108 LEU A CB  1 
ATOM   8109 C CG  . LEU A 1 1090 ? 163.192 161.908 205.320 1.00 157.79 ? 1108 LEU A CG  1 
ATOM   8110 C CD1 . LEU A 1 1090 ? 162.668 162.711 204.137 1.00 155.82 ? 1108 LEU A CD1 1 
ATOM   8111 C CD2 . LEU A 1 1090 ? 164.636 162.274 205.615 1.00 153.36 ? 1108 LEU A CD2 1 
ATOM   8112 N N   . ASN A 1 1091 ? 160.764 159.446 207.498 1.00 186.75 ? 1109 ASN A N   1 
ATOM   8113 C CA  . ASN A 1 1091 ? 160.658 157.991 207.446 1.00 190.53 ? 1109 ASN A CA  1 
ATOM   8114 C C   . ASN A 1 1091 ? 159.327 157.552 206.848 1.00 191.69 ? 1109 ASN A C   1 
ATOM   8115 O O   . ASN A 1 1091 ? 159.287 156.653 206.002 1.00 194.15 ? 1109 ASN A O   1 
ATOM   8116 C CB  . ASN A 1 1091 ? 160.842 157.398 208.843 1.00 191.34 ? 1109 ASN A CB  1 
ATOM   8117 C CG  . ASN A 1 1091 ? 162.251 157.571 209.367 1.00 189.23 ? 1109 ASN A CG  1 
ATOM   8118 O OD1 . ASN A 1 1091 ? 163.103 158.165 208.706 1.00 186.74 ? 1109 ASN A OD1 1 
ATOM   8119 N ND2 . ASN A 1 1091 ? 162.509 157.045 210.558 1.00 190.05 ? 1109 ASN A ND2 1 
ATOM   8120 N N   . MET A 1 1092 ? 158.221 158.166 207.278 1.00 190.88 ? 1110 MET A N   1 
ATOM   8121 C CA  . MET A 1 1092 ? 156.933 157.790 206.691 1.00 192.92 ? 1110 MET A CA  1 
ATOM   8122 C C   . MET A 1 1092 ? 156.687 158.474 205.349 1.00 186.58 ? 1110 MET A C   1 
ATOM   8123 O O   . MET A 1 1092 ? 155.742 158.099 204.647 1.00 184.96 ? 1110 MET A O   1 
ATOM   8124 C CB  . MET A 1 1092 ? 155.762 158.054 207.659 1.00 197.72 ? 1110 MET A CB  1 
ATOM   8125 C CG  . MET A 1 1092 ? 155.611 159.435 208.306 1.00 195.22 ? 1110 MET A CG  1 
ATOM   8126 S SD  . MET A 1 1092 ? 155.239 160.810 207.206 1.00 193.26 ? 1110 MET A SD  1 
ATOM   8127 C CE  . MET A 1 1092 ? 153.719 160.245 206.445 1.00 184.18 ? 1110 MET A CE  1 
ATOM   8128 N N   . LEU A 1 1093 ? 157.506 159.463 204.978 1.00 180.69 ? 1111 LEU A N   1 
ATOM   8129 C CA  . LEU A 1 1093 ? 157.481 159.989 203.619 1.00 178.95 ? 1111 LEU A CA  1 
ATOM   8130 C C   . LEU A 1 1093 ? 158.136 159.029 202.634 1.00 180.41 ? 1111 LEU A C   1 
ATOM   8131 O O   . LEU A 1 1093 ? 157.593 158.785 201.551 1.00 176.03 ? 1111 LEU A O   1 
ATOM   8132 C CB  . LEU A 1 1093 ? 158.174 161.353 203.577 1.00 178.93 ? 1111 LEU A CB  1 
ATOM   8133 C CG  . LEU A 1 1093 ? 158.407 162.007 202.209 1.00 174.32 ? 1111 LEU A CG  1 
ATOM   8134 C CD1 . LEU A 1 1093 ? 157.132 162.080 201.383 1.00 168.64 ? 1111 LEU A CD1 1 
ATOM   8135 C CD2 . LEU A 1 1093 ? 159.003 163.394 202.386 1.00 177.97 ? 1111 LEU A CD2 1 
ATOM   8136 N N   . THR A 1 1094 ? 159.301 158.480 202.980 1.00 185.19 ? 1112 THR A N   1 
ATOM   8137 C CA  . THR A 1 1094 ? 159.967 157.551 202.077 1.00 188.87 ? 1112 THR A CA  1 
ATOM   8138 C C   . THR A 1 1094 ? 159.317 156.173 202.073 1.00 191.91 ? 1112 THR A C   1 
ATOM   8139 O O   . THR A 1 1094 ? 159.505 155.425 201.108 1.00 190.56 ? 1112 THR A O   1 
ATOM   8140 C CB  . THR A 1 1094 ? 161.461 157.438 202.422 1.00 187.54 ? 1112 THR A CB  1 
ATOM   8141 O OG1 . THR A 1 1094 ? 162.146 156.746 201.370 1.00 182.35 ? 1112 THR A OG1 1 
ATOM   8142 C CG2 . THR A 1 1094 ? 161.696 156.714 203.743 1.00 191.14 ? 1112 THR A CG2 1 
ATOM   8143 N N   . TRP A 1 1095 ? 158.556 155.821 203.113 1.00 193.41 ? 1113 TRP A N   1 
ATOM   8144 C CA  . TRP A 1 1095 ? 157.725 154.625 203.029 1.00 193.05 ? 1113 TRP A CA  1 
ATOM   8145 C C   . TRP A 1 1095 ? 156.628 154.796 201.989 1.00 190.24 ? 1113 TRP A C   1 
ATOM   8146 O O   . TRP A 1 1095 ? 156.226 153.821 201.345 1.00 190.20 ? 1113 TRP A O   1 
ATOM   8147 C CB  . TRP A 1 1095 ? 157.107 154.298 204.392 1.00 193.50 ? 1113 TRP A CB  1 
ATOM   8148 C CG  . TRP A 1 1095 ? 158.096 153.923 205.467 1.00 198.97 ? 1113 TRP A CG  1 
ATOM   8149 C CD1 . TRP A 1 1095 ? 159.388 153.512 205.294 1.00 199.85 ? 1113 TRP A CD1 1 
ATOM   8150 C CD2 . TRP A 1 1095 ? 157.863 153.921 206.882 1.00 205.25 ? 1113 TRP A CD2 1 
ATOM   8151 N NE1 . TRP A 1 1095 ? 159.972 153.259 206.511 1.00 201.20 ? 1113 TRP A NE1 1 
ATOM   8152 C CE2 . TRP A 1 1095 ? 159.057 153.502 207.502 1.00 205.14 ? 1113 TRP A CE2 1 
ATOM   8153 C CE3 . TRP A 1 1095 ? 156.761 154.234 207.684 1.00 206.91 ? 1113 TRP A CE3 1 
ATOM   8154 C CZ2 . TRP A 1 1095 ? 159.180 153.389 208.885 1.00 205.98 ? 1113 TRP A CZ2 1 
ATOM   8155 C CZ3 . TRP A 1 1095 ? 156.886 154.122 209.057 1.00 204.71 ? 1113 TRP A CZ3 1 
ATOM   8156 C CH2 . TRP A 1 1095 ? 158.086 153.703 209.643 1.00 204.82 ? 1113 TRP A CH2 1 
ATOM   8157 N N   . ARG A 1 1096 ? 156.136 156.022 201.809 1.00 187.14 ? 1114 ARG A N   1 
ATOM   8158 C CA  . ARG A 1 1096 ? 155.165 156.312 200.764 1.00 187.45 ? 1114 ARG A CA  1 
ATOM   8159 C C   . ARG A 1 1096 ? 155.783 156.331 199.373 1.00 187.21 ? 1114 ARG A C   1 
ATOM   8160 O O   . ARG A 1 1096 ? 155.041 156.309 198.385 1.00 187.96 ? 1114 ARG A O   1 
ATOM   8161 C CB  . ARG A 1 1096 ? 154.495 157.660 201.032 1.00 185.34 ? 1114 ARG A CB  1 
ATOM   8162 C CG  . ARG A 1 1096 ? 153.410 157.623 202.087 1.00 184.61 ? 1114 ARG A CG  1 
ATOM   8163 C CD  . ARG A 1 1096 ? 152.537 158.855 201.996 1.00 184.50 ? 1114 ARG A CD  1 
ATOM   8164 N NE  . ARG A 1 1096 ? 151.564 158.919 203.081 1.00 189.04 ? 1114 ARG A NE  1 
ATOM   8165 C CZ  . ARG A 1 1096 ? 150.472 159.674 203.082 1.00 193.48 ? 1114 ARG A CZ  1 
ATOM   8166 N NH1 . ARG A 1 1096 ? 150.166 160.461 202.062 1.00 194.36 ? 1114 ARG A NH1 1 
ATOM   8167 N NH2 . ARG A 1 1096 ? 149.664 159.642 204.138 1.00 195.94 ? 1114 ARG A NH2 1 
ATOM   8168 N N   . ALA A 1 1097 ? 157.109 156.374 199.268 1.00 184.26 ? 1115 ALA A N   1 
ATOM   8169 C CA  . ALA A 1 1097 ? 157.755 156.385 197.968 1.00 182.97 ? 1115 ALA A CA  1 
ATOM   8170 C C   . ALA A 1 1097 ? 157.574 155.041 197.271 1.00 187.19 ? 1115 ALA A C   1 
ATOM   8171 O O   . ALA A 1 1097 ? 157.337 154.008 197.903 1.00 190.52 ? 1115 ALA A O   1 
ATOM   8172 C CB  . ALA A 1 1097 ? 159.241 156.703 198.114 1.00 182.89 ? 1115 ALA A CB  1 
ATOM   8173 N N   . GLU A 1 1098 ? 157.693 155.070 195.945 1.00 186.59 ? 1116 GLU A N   1 
ATOM   8174 C CA  . GLU A 1 1098 ? 157.510 153.901 195.085 1.00 191.72 ? 1116 GLU A CA  1 
ATOM   8175 C C   . GLU A 1 1098 ? 158.841 153.612 194.399 1.00 192.73 ? 1116 GLU A C   1 
ATOM   8176 O O   . GLU A 1 1098 ? 159.178 154.246 193.394 1.00 189.73 ? 1116 GLU A O   1 
ATOM   8177 C CB  . GLU A 1 1098 ? 156.393 154.141 194.072 1.00 194.86 ? 1116 GLU A CB  1 
ATOM   8178 C CG  . GLU A 1 1098 ? 155.009 154.343 194.699 1.00 201.11 ? 1116 GLU A CG  1 
ATOM   8179 C CD  . GLU A 1 1098 ? 154.297 153.038 195.041 1.00 206.44 ? 1116 GLU A CD  1 
ATOM   8180 O OE1 . GLU A 1 1098 ? 154.584 151.999 194.411 1.00 213.56 ? 1116 GLU A OE1 1 
ATOM   8181 O OE2 . GLU A 1 1098 ? 153.442 153.055 195.952 1.00 198.29 ? 1116 GLU A OE2 1 
ATOM   8182 N N   . GLN A 1 1099 ? 159.590 152.652 194.944 1.00 194.90 ? 1117 GLN A N   1 
ATOM   8183 C CA  . GLN A 1 1099 ? 160.916 152.284 194.452 1.00 188.85 ? 1117 GLN A CA  1 
ATOM   8184 C C   . GLN A 1 1099 ? 160.805 150.965 193.703 1.00 193.12 ? 1117 GLN A C   1 
ATOM   8185 O O   . GLN A 1 1099 ? 160.456 149.936 194.293 1.00 196.12 ? 1117 GLN A O   1 
ATOM   8186 C CB  . GLN A 1 1099 ? 161.918 152.166 195.598 1.00 182.38 ? 1117 GLN A CB  1 
ATOM   8187 C CG  . GLN A 1 1099 ? 161.803 153.247 196.655 1.00 185.89 ? 1117 GLN A CG  1 
ATOM   8188 C CD  . GLN A 1 1099 ? 160.973 152.811 197.845 1.00 190.63 ? 1117 GLN A CD  1 
ATOM   8189 O OE1 . GLN A 1 1099 ? 160.047 152.011 197.714 1.00 193.52 ? 1117 GLN A OE1 1 
ATOM   8190 N NE2 . GLN A 1 1099 ? 161.303 153.337 199.017 1.00 189.76 ? 1117 GLN A NE2 1 
ATOM   8191 N N   . GLU A 1 1100 ? 161.094 150.999 192.404 1.00 191.59 ? 1118 GLU A N   1 
ATOM   8192 C CA  . GLU A 1 1100 ? 161.146 149.804 191.572 1.00 193.54 ? 1118 GLU A CA  1 
ATOM   8193 C C   . GLU A 1 1100 ? 162.304 149.957 190.599 1.00 185.63 ? 1118 GLU A C   1 
ATOM   8194 O O   . GLU A 1 1100 ? 162.317 150.891 189.790 1.00 180.06 ? 1118 GLU A O   1 
ATOM   8195 C CB  . GLU A 1 1100 ? 159.832 149.578 190.810 1.00 199.72 ? 1118 GLU A CB  1 
ATOM   8196 C CG  . GLU A 1 1100 ? 158.553 149.605 191.663 1.00 202.81 ? 1118 GLU A CG  1 
ATOM   8197 C CD  . GLU A 1 1100 ? 158.043 151.004 191.981 1.00 205.27 ? 1118 GLU A CD  1 
ATOM   8198 O OE1 . GLU A 1 1100 ? 158.569 151.989 191.420 1.00 206.57 ? 1118 GLU A OE1 1 
ATOM   8199 O OE2 . GLU A 1 1100 ? 157.110 151.113 192.802 1.00 207.61 ? 1118 GLU A OE2 1 
ATOM   8200 N N   . GLY A 1 1101 ? 163.270 149.049 190.682 1.00 184.53 ? 1119 GLY A N   1 
ATOM   8201 C CA  . GLY A 1 1101 ? 164.423 149.090 189.800 1.00 172.52 ? 1119 GLY A CA  1 
ATOM   8202 C C   . GLY A 1 1101 ? 165.268 150.338 189.940 1.00 173.80 ? 1119 GLY A C   1 
ATOM   8203 O O   . GLY A 1 1101 ? 165.671 150.924 188.926 1.00 171.61 ? 1119 GLY A O   1 
ATOM   8204 N N   . GLY A 1 1102 ? 165.541 150.765 191.169 1.00 172.64 ? 1120 GLY A N   1 
ATOM   8205 C CA  . GLY A 1 1102 ? 166.377 151.932 191.389 1.00 164.78 ? 1120 GLY A CA  1 
ATOM   8206 C C   . GLY A 1 1102 ? 165.767 153.207 190.850 1.00 170.49 ? 1120 GLY A C   1 
ATOM   8207 O O   . GLY A 1 1102 ? 166.478 154.023 190.251 1.00 162.24 ? 1120 GLY A O   1 
ATOM   8208 N N   . MET A 1 1103 ? 164.458 153.391 191.039 1.00 171.66 ? 1121 MET A N   1 
ATOM   8209 C CA  . MET A 1 1103 ? 163.728 154.560 190.541 1.00 169.27 ? 1121 MET A CA  1 
ATOM   8210 C C   . MET A 1 1103 ? 162.703 154.933 191.610 1.00 174.61 ? 1121 MET A C   1 
ATOM   8211 O O   . MET A 1 1103 ? 161.636 154.319 191.700 1.00 185.10 ? 1121 MET A O   1 
ATOM   8212 C CB  . MET A 1 1103 ? 163.062 154.253 189.201 1.00 174.70 ? 1121 MET A CB  1 
ATOM   8213 C CG  . MET A 1 1103 ? 163.955 154.275 187.945 1.00 176.29 ? 1121 MET A CG  1 
ATOM   8214 S SD  . MET A 1 1103 ? 165.330 155.441 187.715 1.00 178.09 ? 1121 MET A SD  1 
ATOM   8215 C CE  . MET A 1 1103 ? 164.691 157.033 188.254 1.00 162.94 ? 1121 MET A CE  1 
ATOM   8216 N N   . GLN A 1 1104 ? 163.028 155.949 192.407 1.00 169.06 ? 1122 GLN A N   1 
ATOM   8217 C CA  . GLN A 1 1104 ? 162.205 156.383 193.530 1.00 170.34 ? 1122 GLN A CA  1 
ATOM   8218 C C   . GLN A 1 1104 ? 161.467 157.663 193.166 1.00 168.84 ? 1122 GLN A C   1 
ATOM   8219 O O   . GLN A 1 1104 ? 162.076 158.620 192.676 1.00 167.20 ? 1122 GLN A O   1 
ATOM   8220 C CB  . GLN A 1 1104 ? 163.062 156.609 194.776 1.00 161.65 ? 1122 GLN A CB  1 
ATOM   8221 C CG  . GLN A 1 1104 ? 162.263 156.938 196.033 1.00 165.70 ? 1122 GLN A CG  1 
ATOM   8222 C CD  . GLN A 1 1104 ? 163.031 156.687 197.327 1.00 168.96 ? 1122 GLN A CD  1 
ATOM   8223 O OE1 . GLN A 1 1104 ? 163.999 155.927 197.359 1.00 166.17 ? 1122 GLN A OE1 1 
ATOM   8224 N NE2 . GLN A 1 1104 ? 162.599 157.337 198.402 1.00 174.69 ? 1122 GLN A NE2 1 
ATOM   8225 N N   . PHE A 1 1105 ? 160.160 157.674 193.408 1.00 167.38 ? 1123 PHE A N   1 
ATOM   8226 C CA  . PHE A 1 1105 ? 159.325 158.844 193.174 1.00 164.07 ? 1123 PHE A CA  1 
ATOM   8227 C C   . PHE A 1 1105 ? 158.077 158.692 194.040 1.00 171.80 ? 1123 PHE A C   1 
ATOM   8228 O O   . PHE A 1 1105 ? 158.016 157.816 194.909 1.00 175.66 ? 1123 PHE A O   1 
ATOM   8229 C CB  . PHE A 1 1105 ? 159.031 158.988 191.674 1.00 158.25 ? 1123 PHE A CB  1 
ATOM   8230 C CG  . PHE A 1 1105 ? 158.622 157.707 191.012 1.00 161.65 ? 1123 PHE A CG  1 
ATOM   8231 C CD1 . PHE A 1 1105 ? 157.318 157.253 191.099 1.00 168.21 ? 1123 PHE A CD1 1 
ATOM   8232 C CD2 . PHE A 1 1105 ? 159.541 156.951 190.307 1.00 166.94 ? 1123 PHE A CD2 1 
ATOM   8233 C CE1 . PHE A 1 1105 ? 156.938 156.075 190.490 1.00 174.42 ? 1123 PHE A CE1 1 
ATOM   8234 C CE2 . PHE A 1 1105 ? 159.167 155.772 189.697 1.00 173.64 ? 1123 PHE A CE2 1 
ATOM   8235 C CZ  . PHE A 1 1105 ? 157.864 155.333 189.789 1.00 176.60 ? 1123 PHE A CZ  1 
ATOM   8236 N N   . TRP A 1 1106 ? 157.077 159.546 193.808 1.00 172.63 ? 1124 TRP A N   1 
ATOM   8237 C CA  . TRP A 1 1106 ? 155.875 159.583 194.629 1.00 175.42 ? 1124 TRP A CA  1 
ATOM   8238 C C   . TRP A 1 1106 ? 154.634 159.652 193.752 1.00 181.44 ? 1124 TRP A C   1 
ATOM   8239 O O   . TRP A 1 1106 ? 154.664 160.156 192.626 1.00 178.09 ? 1124 TRP A O   1 
ATOM   8240 C CB  . TRP A 1 1106 ? 155.904 160.770 195.594 1.00 173.22 ? 1124 TRP A CB  1 
ATOM   8241 C CG  . TRP A 1 1106 ? 156.571 160.431 196.874 1.00 175.59 ? 1124 TRP A CG  1 
ATOM   8242 C CD1 . TRP A 1 1106 ? 156.012 159.810 197.949 1.00 182.52 ? 1124 TRP A CD1 1 
ATOM   8243 C CD2 . TRP A 1 1106 ? 157.937 160.671 197.213 1.00 173.63 ? 1124 TRP A CD2 1 
ATOM   8244 N NE1 . TRP A 1 1106 ? 156.944 159.656 198.944 1.00 180.82 ? 1124 TRP A NE1 1 
ATOM   8245 C CE2 . TRP A 1 1106 ? 158.136 160.178 198.516 1.00 177.97 ? 1124 TRP A CE2 1 
ATOM   8246 C CE3 . TRP A 1 1106 ? 159.012 161.261 196.543 1.00 170.77 ? 1124 TRP A CE3 1 
ATOM   8247 C CZ2 . TRP A 1 1106 ? 159.363 160.256 199.162 1.00 179.16 ? 1124 TRP A CZ2 1 
ATOM   8248 C CZ3 . TRP A 1 1106 ? 160.229 161.338 197.186 1.00 174.03 ? 1124 TRP A CZ3 1 
ATOM   8249 C CH2 . TRP A 1 1106 ? 160.396 160.837 198.482 1.00 179.51 ? 1124 TRP A CH2 1 
ATOM   8250 N N   . VAL A 1 1107 ? 153.535 159.137 194.298 1.00 188.74 ? 1125 VAL A N   1 
ATOM   8251 C CA  . VAL A 1 1107 ? 152.259 159.102 193.593 1.00 194.22 ? 1125 VAL A CA  1 
ATOM   8252 C C   . VAL A 1 1107 ? 151.582 160.463 193.695 1.00 200.04 ? 1125 VAL A C   1 
ATOM   8253 O O   . VAL A 1 1107 ? 151.672 161.154 194.716 1.00 195.29 ? 1125 VAL A O   1 
ATOM   8254 C CB  . VAL A 1 1107 ? 151.346 157.979 194.137 1.00 186.79 ? 1125 VAL A CB  1 
ATOM   8255 C CG1 . VAL A 1 1107 ? 151.930 156.615 193.803 1.00 182.79 ? 1125 VAL A CG1 1 
ATOM   8256 C CG2 . VAL A 1 1107 ? 151.091 158.104 195.656 1.00 169.25 ? 1125 VAL A CG2 1 
ATOM   8257 N N   . SER A 1 1108 ? 150.887 160.843 192.627 1.00 205.21 ? 1126 SER A N   1 
ATOM   8258 C CA  . SER A 1 1108 ? 150.146 162.092 192.558 1.00 209.95 ? 1126 SER A CA  1 
ATOM   8259 C C   . SER A 1 1108 ? 148.674 161.849 192.868 1.00 218.65 ? 1126 SER A C   1 
ATOM   8260 O O   . SER A 1 1108 ? 148.141 160.756 192.662 1.00 218.42 ? 1126 SER A O   1 
ATOM   8261 C CB  . SER A 1 1108 ? 150.290 162.729 191.173 1.00 210.75 ? 1126 SER A CB  1 
ATOM   8262 O OG  . SER A 1 1108 ? 151.653 162.935 190.848 1.00 201.13 ? 1126 SER A OG  1 
ATOM   8263 N N   . SER A 1 1109 ? 148.018 162.894 193.377 1.00 224.66 ? 1127 SER A N   1 
ATOM   8264 C CA  . SER A 1 1109 ? 146.595 162.790 193.686 1.00 229.84 ? 1127 SER A CA  1 
ATOM   8265 C C   . SER A 1 1109 ? 145.772 162.574 192.424 1.00 233.74 ? 1127 SER A C   1 
ATOM   8266 O O   . SER A 1 1109 ? 144.852 161.747 192.410 1.00 234.35 ? 1127 SER A O   1 
ATOM   8267 C CB  . SER A 1 1109 ? 146.127 164.046 194.420 1.00 228.33 ? 1127 SER A CB  1 
ATOM   8268 O OG  . SER A 1 1109 ? 146.404 165.210 193.662 1.00 230.29 ? 1127 SER A OG  1 
ATOM   8269 N N   . GLU A 1 1110 ? 146.089 163.300 191.356 1.00 236.42 ? 1128 GLU A N   1 
ATOM   8270 C CA  . GLU A 1 1110 ? 145.368 163.177 190.095 1.00 235.28 ? 1128 GLU A CA  1 
ATOM   8271 C C   . GLU A 1 1110 ? 145.933 162.033 189.261 1.00 231.00 ? 1128 GLU A C   1 
ATOM   8272 O O   . GLU A 1 1110 ? 146.815 162.237 188.427 1.00 227.56 ? 1128 GLU A O   1 
ATOM   8273 C CB  . GLU A 1 1110 ? 145.439 164.487 189.308 1.00 234.48 ? 1128 GLU A CB  1 
ATOM   8274 C CG  . GLU A 1 1110 ? 144.808 165.679 190.026 1.00 232.11 ? 1128 GLU A CG  1 
ATOM   8275 C CD  . GLU A 1 1110 ? 145.775 166.429 190.932 1.00 232.48 ? 1128 GLU A CD  1 
ATOM   8276 O OE1 . GLU A 1 1110 ? 146.905 165.943 191.157 1.00 234.07 ? 1128 GLU A OE1 1 
ATOM   8277 O OE2 . GLU A 1 1110 ? 145.400 167.514 191.424 1.00 228.94 ? 1128 GLU A OE2 1 
ATOM   8278 N N   . SER A 1 1121 ? 155.462 169.116 187.473 1.00 193.23 ? 1139 SER A N   1 
ATOM   8279 C CA  . SER A 1 1121 ? 154.202 168.875 188.163 1.00 191.71 ? 1139 SER A CA  1 
ATOM   8280 C C   . SER A 1 1121 ? 154.448 168.642 189.652 1.00 194.75 ? 1139 SER A C   1 
ATOM   8281 O O   . SER A 1 1121 ? 155.557 168.855 190.144 1.00 196.78 ? 1139 SER A O   1 
ATOM   8282 C CB  . SER A 1 1121 ? 153.474 167.679 187.546 1.00 187.15 ? 1139 SER A CB  1 
ATOM   8283 O OG  . SER A 1 1121 ? 152.281 167.392 188.254 1.00 179.70 ? 1139 SER A OG  1 
ATOM   8284 N N   . LEU A 1 1122 ? 153.401 168.202 190.356 1.00 194.22 ? 1140 LEU A N   1 
ATOM   8285 C CA  . LEU A 1 1122 ? 153.485 168.006 191.801 1.00 194.31 ? 1140 LEU A CA  1 
ATOM   8286 C C   . LEU A 1 1122 ? 154.549 166.979 192.177 1.00 193.47 ? 1140 LEU A C   1 
ATOM   8287 O O   . LEU A 1 1122 ? 155.198 167.105 193.232 1.00 193.56 ? 1140 LEU A O   1 
ATOM   8288 C CB  . LEU A 1 1122 ? 152.121 167.565 192.338 1.00 192.90 ? 1140 LEU A CB  1 
ATOM   8289 C CG  . LEU A 1 1122 ? 151.770 168.096 193.722 1.00 193.48 ? 1140 LEU A CG  1 
ATOM   8290 C CD1 . LEU A 1 1122 ? 151.284 169.533 193.629 1.00 190.88 ? 1140 LEU A CD1 1 
ATOM   8291 C CD2 . LEU A 1 1122 ? 150.740 167.210 194.397 1.00 199.77 ? 1140 LEU A CD2 1 
ATOM   8292 N N   . ASP A 1 1123 ? 154.725 165.956 191.334 1.00 193.91 ? 1141 ASP A N   1 
ATOM   8293 C CA  . ASP A 1 1123 ? 155.716 164.915 191.599 1.00 191.96 ? 1141 ASP A CA  1 
ATOM   8294 C C   . ASP A 1 1123 ? 157.119 165.495 191.731 1.00 187.73 ? 1141 ASP A C   1 
ATOM   8295 O O   . ASP A 1 1123 ? 157.884 165.080 192.611 1.00 185.38 ? 1141 ASP A O   1 
ATOM   8296 C CB  . ASP A 1 1123 ? 155.693 163.855 190.496 1.00 194.41 ? 1141 ASP A CB  1 
ATOM   8297 C CG  . ASP A 1 1123 ? 155.784 164.451 189.103 1.00 199.05 ? 1141 ASP A CG  1 
ATOM   8298 O OD1 . ASP A 1 1123 ? 155.786 165.695 188.994 1.00 201.57 ? 1141 ASP A OD1 1 
ATOM   8299 O OD2 . ASP A 1 1123 ? 155.852 163.679 188.123 1.00 200.82 ? 1141 ASP A OD2 1 
ATOM   8300 N N   . ILE A 1 1124 ? 157.469 166.466 190.887 1.00 186.55 ? 1142 ILE A N   1 
ATOM   8301 C CA  . ILE A 1 1124 ? 158.800 167.058 190.963 1.00 179.54 ? 1142 ILE A CA  1 
ATOM   8302 C C   . ILE A 1 1124 ? 158.962 167.821 192.270 1.00 177.13 ? 1142 ILE A C   1 
ATOM   8303 O O   . ILE A 1 1124 ? 160.037 167.807 192.878 1.00 177.74 ? 1142 ILE A O   1 
ATOM   8304 C CB  . ILE A 1 1124 ? 159.087 167.961 189.743 1.00 179.72 ? 1142 ILE A CB  1 
ATOM   8305 C CG1 . ILE A 1 1124 ? 158.843 167.214 188.416 1.00 183.10 ? 1142 ILE A CG1 1 
ATOM   8306 C CG2 . ILE A 1 1124 ? 160.544 168.495 189.816 1.00 181.12 ? 1142 ILE A CG2 1 
ATOM   8307 C CD1 . ILE A 1 1124 ? 158.944 168.081 187.165 1.00 190.13 ? 1142 ILE A CD1 1 
ATOM   8308 N N   . GLU A 1 1125 ? 157.904 168.490 192.731 1.00 178.86 ? 1143 GLU A N   1 
ATOM   8309 C CA  . GLU A 1 1125 ? 158.036 169.301 193.939 1.00 177.94 ? 1143 GLU A CA  1 
ATOM   8310 C C   . GLU A 1 1125 ? 158.201 168.408 195.163 1.00 170.03 ? 1143 GLU A C   1 
ATOM   8311 O O   . GLU A 1 1125 ? 159.060 168.665 196.020 1.00 164.33 ? 1143 GLU A O   1 
ATOM   8312 C CB  . GLU A 1 1125 ? 156.855 170.275 194.130 1.00 188.28 ? 1143 GLU A CB  1 
ATOM   8313 C CG  . GLU A 1 1125 ? 156.064 170.748 192.880 1.00 197.51 ? 1143 GLU A CG  1 
ATOM   8314 C CD  . GLU A 1 1125 ? 154.748 171.420 193.217 1.00 202.96 ? 1143 GLU A CD  1 
ATOM   8315 O OE1 . GLU A 1 1125 ? 154.567 171.838 194.378 1.00 204.91 ? 1143 GLU A OE1 1 
ATOM   8316 O OE2 . GLU A 1 1125 ? 153.888 171.521 192.316 1.00 201.39 ? 1143 GLU A OE2 1 
ATOM   8317 N N   . VAL A 1 1126 ? 157.397 167.341 195.256 1.00 170.63 ? 1144 VAL A N   1 
ATOM   8318 C CA  . VAL A 1 1126 ? 157.584 166.409 196.369 1.00 169.74 ? 1144 VAL A CA  1 
ATOM   8319 C C   . VAL A 1 1126 ? 158.964 165.763 196.300 1.00 170.37 ? 1144 VAL A C   1 
ATOM   8320 O O   . VAL A 1 1126 ? 159.624 165.605 197.335 1.00 173.93 ? 1144 VAL A O   1 
ATOM   8321 C CB  . VAL A 1 1126 ? 156.454 165.352 196.428 1.00 175.49 ? 1144 VAL A CB  1 
ATOM   8322 C CG1 . VAL A 1 1126 ? 156.406 164.492 195.187 1.00 179.33 ? 1144 VAL A CG1 1 
ATOM   8323 C CG2 . VAL A 1 1126 ? 156.594 164.446 197.663 1.00 176.28 ? 1144 VAL A CG2 1 
ATOM   8324 N N   . ALA A 1 1127 ? 159.435 165.401 195.103 1.00 171.40 ? 1145 ALA A N   1 
ATOM   8325 C CA  . ALA A 1 1127 ? 160.747 164.771 194.999 1.00 164.72 ? 1145 ALA A CA  1 
ATOM   8326 C C   . ALA A 1 1127 ? 161.856 165.715 195.447 1.00 157.91 ? 1145 ALA A C   1 
ATOM   8327 O O   . ALA A 1 1127 ? 162.743 165.321 196.215 1.00 156.85 ? 1145 ALA A O   1 
ATOM   8328 C CB  . ALA A 1 1127 ? 160.986 164.304 193.565 1.00 164.05 ? 1145 ALA A CB  1 
ATOM   8329 N N   . ALA A 1 1128 ? 161.812 166.970 194.995 1.00 159.35 ? 1146 ALA A N   1 
ATOM   8330 C CA  . ALA A 1 1128 ? 162.858 167.920 195.350 1.00 158.86 ? 1146 ALA A CA  1 
ATOM   8331 C C   . ALA A 1 1128 ? 162.850 168.223 196.841 1.00 155.65 ? 1146 ALA A C   1 
ATOM   8332 O O   . ALA A 1 1128 ? 163.914 168.300 197.470 1.00 152.81 ? 1146 ALA A O   1 
ATOM   8333 C CB  . ALA A 1 1128 ? 162.695 169.205 194.541 1.00 166.44 ? 1146 ALA A CB  1 
ATOM   8334 N N   . TYR A 1 1129 ? 161.665 168.393 197.434 1.00 156.33 ? 1147 TYR A N   1 
ATOM   8335 C CA  . TYR A 1 1129 ? 161.629 168.692 198.860 1.00 154.09 ? 1147 TYR A CA  1 
ATOM   8336 C C   . TYR A 1 1129 ? 162.048 167.488 199.692 1.00 150.59 ? 1147 TYR A C   1 
ATOM   8337 O O   . TYR A 1 1129 ? 162.704 167.655 200.728 1.00 149.91 ? 1147 TYR A O   1 
ATOM   8338 C CB  . TYR A 1 1129 ? 160.238 169.187 199.260 1.00 160.73 ? 1147 TYR A CB  1 
ATOM   8339 C CG  . TYR A 1 1129 ? 160.017 170.658 198.960 1.00 164.86 ? 1147 TYR A CG  1 
ATOM   8340 C CD1 . TYR A 1 1129 ? 160.750 171.643 199.612 1.00 159.86 ? 1147 TYR A CD1 1 
ATOM   8341 C CD2 . TYR A 1 1129 ? 159.089 171.059 198.011 1.00 172.36 ? 1147 TYR A CD2 1 
ATOM   8342 C CE1 . TYR A 1 1129 ? 160.559 172.979 199.334 1.00 164.00 ? 1147 TYR A CE1 1 
ATOM   8343 C CE2 . TYR A 1 1129 ? 158.890 172.396 197.728 1.00 175.21 ? 1147 TYR A CE2 1 
ATOM   8344 C CZ  . TYR A 1 1129 ? 159.628 173.350 198.392 1.00 173.75 ? 1147 TYR A CZ  1 
ATOM   8345 O OH  . TYR A 1 1129 ? 159.433 174.682 198.112 1.00 186.53 ? 1147 TYR A OH  1 
ATOM   8346 N N   . ALA A 1 1130 ? 161.714 166.272 199.253 1.00 150.24 ? 1148 ALA A N   1 
ATOM   8347 C CA  . ALA A 1 1130 ? 162.209 165.089 199.946 1.00 147.40 ? 1148 ALA A CA  1 
ATOM   8348 C C   . ALA A 1 1130 ? 163.726 164.998 199.859 1.00 146.62 ? 1148 ALA A C   1 
ATOM   8349 O O   . ALA A 1 1130 ? 164.387 164.630 200.836 1.00 146.72 ? 1148 ALA A O   1 
ATOM   8350 C CB  . ALA A 1 1130 ? 161.567 163.833 199.364 1.00 155.49 ? 1148 ALA A CB  1 
ATOM   8351 N N   . LEU A 1 1131 ? 164.295 165.323 198.697 1.00 149.01 ? 1149 LEU A N   1 
ATOM   8352 C CA  . LEU A 1 1131 ? 165.748 165.305 198.555 1.00 143.62 ? 1149 LEU A CA  1 
ATOM   8353 C C   . LEU A 1 1131 ? 166.407 166.330 199.473 1.00 143.13 ? 1149 LEU A C   1 
ATOM   8354 O O   . LEU A 1 1131 ? 167.431 166.042 200.109 1.00 145.22 ? 1149 LEU A O   1 
ATOM   8355 C CB  . LEU A 1 1131 ? 166.119 165.564 197.095 1.00 139.02 ? 1149 LEU A CB  1 
ATOM   8356 C CG  . LEU A 1 1131 ? 167.558 165.341 196.626 1.00 132.68 ? 1149 LEU A CG  1 
ATOM   8357 C CD1 . LEU A 1 1131 ? 168.089 163.963 196.989 1.00 137.82 ? 1149 LEU A CD1 1 
ATOM   8358 C CD2 . LEU A 1 1131 ? 167.638 165.555 195.123 1.00 137.19 ? 1149 LEU A CD2 1 
ATOM   8359 N N   . LEU A 1 1132 ? 165.833 167.532 199.555 1.00 142.03 ? 1150 LEU A N   1 
ATOM   8360 C CA  . LEU A 1 1132 ? 166.381 168.543 200.455 1.00 139.70 ? 1150 LEU A CA  1 
ATOM   8361 C C   . LEU A 1 1132 ? 166.272 168.113 201.912 1.00 141.17 ? 1150 LEU A C   1 
ATOM   8362 O O   . LEU A 1 1132 ? 167.200 168.346 202.696 1.00 141.43 ? 1150 LEU A O   1 
ATOM   8363 C CB  . LEU A 1 1132 ? 165.673 169.880 200.243 1.00 140.43 ? 1150 LEU A CB  1 
ATOM   8364 C CG  . LEU A 1 1132 ? 166.188 170.743 199.089 1.00 138.86 ? 1150 LEU A CG  1 
ATOM   8365 C CD1 . LEU A 1 1132 ? 165.209 171.865 198.798 1.00 151.68 ? 1150 LEU A CD1 1 
ATOM   8366 C CD2 . LEU A 1 1132 ? 167.570 171.312 199.388 1.00 139.05 ? 1150 LEU A CD2 1 
ATOM   8367 N N   . SER A 1 1133 ? 165.155 167.489 202.293 1.00 142.13 ? 1151 SER A N   1 
ATOM   8368 C CA  . SER A 1 1133 ? 165.028 166.970 203.651 1.00 146.55 ? 1151 SER A CA  1 
ATOM   8369 C C   . SER A 1 1133 ? 166.064 165.888 203.923 1.00 144.67 ? 1151 SER A C   1 
ATOM   8370 O O   . SER A 1 1133 ? 166.629 165.822 205.021 1.00 145.32 ? 1151 SER A O   1 
ATOM   8371 C CB  . SER A 1 1133 ? 163.620 166.424 203.875 1.00 158.68 ? 1151 SER A CB  1 
ATOM   8372 O OG  . SER A 1 1133 ? 162.720 167.462 204.217 1.00 170.12 ? 1151 SER A OG  1 
ATOM   8373 N N   . HIS A 1 1134 ? 166.318 165.027 202.935 1.00 143.55 ? 1152 HIS A N   1 
ATOM   8374 C CA  . HIS A 1 1134 ? 167.333 163.990 203.087 1.00 137.76 ? 1152 HIS A CA  1 
ATOM   8375 C C   . HIS A 1 1134 ? 168.707 164.599 203.321 1.00 133.90 ? 1152 HIS A C   1 
ATOM   8376 O O   . HIS A 1 1134 ? 169.462 164.129 204.179 1.00 133.90 ? 1152 HIS A O   1 
ATOM   8377 C CB  . HIS A 1 1134 ? 167.359 163.093 201.850 1.00 135.51 ? 1152 HIS A CB  1 
ATOM   8378 C CG  . HIS A 1 1134 ? 166.454 161.908 201.944 1.00 137.28 ? 1152 HIS A CG  1 
ATOM   8379 N ND1 . HIS A 1 1134 ? 166.612 160.925 202.897 1.00 139.57 ? 1152 HIS A ND1 1 
ATOM   8380 C CD2 . HIS A 1 1134 ? 165.378 161.547 201.206 1.00 139.68 ? 1152 HIS A CD2 1 
ATOM   8381 C CE1 . HIS A 1 1134 ? 165.673 160.009 202.740 1.00 145.02 ? 1152 HIS A CE1 1 
ATOM   8382 N NE2 . HIS A 1 1134 ? 164.911 160.363 201.721 1.00 144.18 ? 1152 HIS A NE2 1 
ATOM   8383 N N   . PHE A 1 1135 ? 169.051 165.641 202.563 1.00 133.14 ? 1153 PHE A N   1 
ATOM   8384 C CA  . PHE A 1 1135 ? 170.340 166.292 202.780 1.00 132.21 ? 1153 PHE A CA  1 
ATOM   8385 C C   . PHE A 1 1135 ? 170.400 166.975 204.138 1.00 132.65 ? 1153 PHE A C   1 
ATOM   8386 O O   . PHE A 1 1135 ? 171.445 166.942 204.798 1.00 136.72 ? 1153 PHE A O   1 
ATOM   8387 C CB  . PHE A 1 1135 ? 170.626 167.322 201.684 1.00 133.17 ? 1153 PHE A CB  1 
ATOM   8388 C CG  . PHE A 1 1135 ? 170.739 166.747 200.290 1.00 138.44 ? 1153 PHE A CG  1 
ATOM   8389 C CD1 . PHE A 1 1135 ? 171.080 165.420 200.065 1.00 140.13 ? 1153 PHE A CD1 1 
ATOM   8390 C CD2 . PHE A 1 1135 ? 170.521 167.563 199.196 1.00 137.05 ? 1153 PHE A CD2 1 
ATOM   8391 C CE1 . PHE A 1 1135 ? 171.180 164.924 198.789 1.00 138.44 ? 1153 PHE A CE1 1 
ATOM   8392 C CE2 . PHE A 1 1135 ? 170.625 167.070 197.917 1.00 139.71 ? 1153 PHE A CE2 1 
ATOM   8393 C CZ  . PHE A 1 1135 ? 170.954 165.748 197.713 1.00 138.79 ? 1153 PHE A CZ  1 
ATOM   8394 N N   . LEU A 1 1136 ? 169.305 167.598 204.573 1.00 132.96 ? 1154 LEU A N   1 
ATOM   8395 C CA  . LEU A 1 1136 ? 169.336 168.323 205.838 1.00 137.25 ? 1154 LEU A CA  1 
ATOM   8396 C C   . LEU A 1 1136 ? 169.494 167.392 207.034 1.00 139.88 ? 1154 LEU A C   1 
ATOM   8397 O O   . LEU A 1 1136 ? 170.044 167.805 208.060 1.00 139.79 ? 1154 LEU A O   1 
ATOM   8398 C CB  . LEU A 1 1136 ? 168.071 169.169 205.995 1.00 140.67 ? 1154 LEU A CB  1 
ATOM   8399 C CG  . LEU A 1 1136 ? 168.130 170.594 205.435 1.00 140.02 ? 1154 LEU A CG  1 
ATOM   8400 C CD1 . LEU A 1 1136 ? 166.737 171.196 205.400 1.00 153.35 ? 1154 LEU A CD1 1 
ATOM   8401 C CD2 . LEU A 1 1136 ? 169.068 171.478 206.253 1.00 134.62 ? 1154 LEU A CD2 1 
ATOM   8402 N N   . GLN A 1 1137 ? 169.032 166.146 206.924 1.00 140.57 ? 1155 GLN A N   1 
ATOM   8403 C CA  . GLN A 1 1137 ? 169.182 165.151 207.978 1.00 141.62 ? 1155 GLN A CA  1 
ATOM   8404 C C   . GLN A 1 1137 ? 170.442 164.303 207.820 1.00 143.91 ? 1155 GLN A C   1 
ATOM   8405 O O   . GLN A 1 1137 ? 170.612 163.327 208.558 1.00 142.53 ? 1155 GLN A O   1 
ATOM   8406 C CB  . GLN A 1 1137 ? 167.950 164.244 208.018 1.00 142.98 ? 1155 GLN A CB  1 
ATOM   8407 C CG  . GLN A 1 1137 ? 166.682 164.950 208.457 1.00 153.22 ? 1155 GLN A CG  1 
ATOM   8408 C CD  . GLN A 1 1137 ? 165.486 164.022 208.493 1.00 167.50 ? 1155 GLN A CD  1 
ATOM   8409 O OE1 . GLN A 1 1137 ? 165.635 162.804 208.574 1.00 171.67 ? 1155 GLN A OE1 1 
ATOM   8410 N NE2 . GLN A 1 1137 ? 164.290 164.594 208.434 1.00 170.93 ? 1155 GLN A NE2 1 
ATOM   8411 N N   . PHE A 1 1138 ? 171.321 164.643 206.873 1.00 145.17 ? 1156 PHE A N   1 
ATOM   8412 C CA  . PHE A 1 1138 ? 172.557 163.899 206.623 1.00 141.51 ? 1156 PHE A CA  1 
ATOM   8413 C C   . PHE A 1 1138 ? 172.293 162.460 206.183 1.00 135.87 ? 1156 PHE A C   1 
ATOM   8414 O O   . PHE A 1 1138 ? 173.149 161.589 206.353 1.00 134.38 ? 1156 PHE A O   1 
ATOM   8415 C CB  . PHE A 1 1138 ? 173.473 163.915 207.850 1.00 143.11 ? 1156 PHE A CB  1 
ATOM   8416 C CG  . PHE A 1 1138 ? 173.661 165.278 208.446 1.00 144.18 ? 1156 PHE A CG  1 
ATOM   8417 C CD1 . PHE A 1 1138 ? 174.450 166.220 207.811 1.00 145.81 ? 1156 PHE A CD1 1 
ATOM   8418 C CD2 . PHE A 1 1138 ? 173.051 165.617 209.641 1.00 144.03 ? 1156 PHE A CD2 1 
ATOM   8419 C CE1 . PHE A 1 1138 ? 174.627 167.476 208.355 1.00 146.50 ? 1156 PHE A CE1 1 
ATOM   8420 C CE2 . PHE A 1 1138 ? 173.225 166.872 210.191 1.00 143.33 ? 1156 PHE A CE2 1 
ATOM   8421 C CZ  . PHE A 1 1138 ? 174.014 167.802 209.547 1.00 145.42 ? 1156 PHE A CZ  1 
ATOM   8422 N N   . GLN A 1 1139 ? 171.114 162.197 205.623 1.00 136.12 ? 1157 GLN A N   1 
ATOM   8423 C CA  . GLN A 1 1139 ? 170.812 160.917 204.979 1.00 136.49 ? 1157 GLN A CA  1 
ATOM   8424 C C   . GLN A 1 1139 ? 171.038 161.030 203.473 1.00 135.12 ? 1157 GLN A C   1 
ATOM   8425 O O   . GLN A 1 1139 ? 170.141 160.828 202.656 1.00 138.77 ? 1157 GLN A O   1 
ATOM   8426 C CB  . GLN A 1 1139 ? 169.382 160.493 205.297 1.00 139.91 ? 1157 GLN A CB  1 
ATOM   8427 C CG  . GLN A 1 1139 ? 169.170 160.041 206.732 1.00 142.15 ? 1157 GLN A CG  1 
ATOM   8428 C CD  . GLN A 1 1139 ? 168.003 159.084 206.868 1.00 147.88 ? 1157 GLN A CD  1 
ATOM   8429 O OE1 . GLN A 1 1139 ? 166.883 159.392 206.461 1.00 148.38 ? 1157 GLN A OE1 1 
ATOM   8430 N NE2 . GLN A 1 1139 ? 168.258 157.914 207.444 1.00 153.90 ? 1157 GLN A NE2 1 
ATOM   8431 N N   . THR A 1 1140 ? 172.279 161.366 203.115 1.00 129.18 ? 1158 THR A N   1 
ATOM   8432 C CA  . THR A 1 1140 ? 172.594 161.649 201.719 1.00 125.23 ? 1158 THR A CA  1 
ATOM   8433 C C   . THR A 1 1140 ? 172.512 160.400 200.852 1.00 123.41 ? 1158 THR A C   1 
ATOM   8434 O O   . THR A 1 1140 ? 172.082 160.481 199.697 1.00 121.99 ? 1158 THR A O   1 
ATOM   8435 C CB  . THR A 1 1140 ? 173.986 162.269 201.615 1.00 119.21 ? 1158 THR A CB  1 
ATOM   8436 O OG1 . THR A 1 1140 ? 174.176 163.200 202.687 1.00 127.97 ? 1158 THR A OG1 1 
ATOM   8437 C CG2 . THR A 1 1140 ? 174.153 162.991 200.288 1.00 113.17 ? 1158 THR A CG2 1 
ATOM   8438 N N   . SER A 1 1141 ? 172.918 159.245 201.383 1.00 128.18 ? 1159 SER A N   1 
ATOM   8439 C CA  . SER A 1 1141 ? 172.948 158.031 200.575 1.00 129.78 ? 1159 SER A CA  1 
ATOM   8440 C C   . SER A 1 1141 ? 171.552 157.583 200.163 1.00 130.86 ? 1159 SER A C   1 
ATOM   8441 O O   . SER A 1 1141 ? 171.391 156.958 199.109 1.00 130.60 ? 1159 SER A O   1 
ATOM   8442 C CB  . SER A 1 1141 ? 173.649 156.910 201.341 1.00 126.65 ? 1159 SER A CB  1 
ATOM   8443 O OG  . SER A 1 1141 ? 172.799 156.366 202.334 1.00 135.72 ? 1159 SER A OG  1 
ATOM   8444 N N   . GLU A 1 1142 ? 170.537 157.878 200.975 1.00 130.89 ? 1160 GLU A N   1 
ATOM   8445 C CA  . GLU A 1 1142 ? 169.180 157.447 200.662 1.00 131.70 ? 1160 GLU A CA  1 
ATOM   8446 C C   . GLU A 1 1142 ? 168.524 158.288 199.575 1.00 132.76 ? 1160 GLU A C   1 
ATOM   8447 O O   . GLU A 1 1142 ? 167.564 157.822 198.952 1.00 138.43 ? 1160 GLU A O   1 
ATOM   8448 C CB  . GLU A 1 1142 ? 168.320 157.479 201.926 1.00 134.91 ? 1160 GLU A CB  1 
ATOM   8449 C CG  . GLU A 1 1142 ? 168.652 156.378 202.922 1.00 142.20 ? 1160 GLU A CG  1 
ATOM   8450 C CD  . GLU A 1 1142 ? 169.819 156.734 203.821 1.00 146.49 ? 1160 GLU A CD  1 
ATOM   8451 O OE1 . GLU A 1 1142 ? 170.608 157.628 203.448 1.00 141.10 ? 1160 GLU A OE1 1 
ATOM   8452 O OE2 . GLU A 1 1142 ? 169.952 156.116 204.897 1.00 155.40 ? 1160 GLU A OE2 1 
ATOM   8453 N N   . GLY A 1 1143 ? 169.010 159.502 199.331 1.00 128.91 ? 1161 GLY A N   1 
ATOM   8454 C CA  . GLY A 1 1143 ? 168.447 160.350 198.302 1.00 135.70 ? 1161 GLY A CA  1 
ATOM   8455 C C   . GLY A 1 1143 ? 168.919 160.070 196.895 1.00 137.86 ? 1161 GLY A C   1 
ATOM   8456 O O   . GLY A 1 1143 ? 168.479 160.750 195.963 1.00 143.24 ? 1161 GLY A O   1 
ATOM   8457 N N   . ILE A 1 1144 ? 169.810 159.094 196.708 1.00 132.27 ? 1162 ILE A N   1 
ATOM   8458 C CA  . ILE A 1 1144 ? 170.365 158.838 195.376 1.00 131.55 ? 1162 ILE A CA  1 
ATOM   8459 C C   . ILE A 1 1144 ? 169.305 158.390 194.376 1.00 138.26 ? 1162 ILE A C   1 
ATOM   8460 O O   . ILE A 1 1144 ? 169.320 158.883 193.236 1.00 141.70 ? 1162 ILE A O   1 
ATOM   8461 C CB  . ILE A 1 1144 ? 171.541 157.852 195.473 1.00 124.74 ? 1162 ILE A CB  1 
ATOM   8462 C CG1 . ILE A 1 1144 ? 172.647 158.370 196.414 1.00 119.87 ? 1162 ILE A CG1 1 
ATOM   8463 C CG2 . ILE A 1 1144 ? 172.107 157.565 194.085 1.00 124.50 ? 1162 ILE A CG2 1 
ATOM   8464 C CD1 . ILE A 1 1144 ? 173.289 159.700 196.024 1.00 108.96 ? 1162 ILE A CD1 1 
ATOM   8465 N N   . PRO A 1 1145 ? 168.396 157.457 194.691 1.00 139.30 ? 1163 PRO A N   1 
ATOM   8466 C CA  . PRO A 1 1145 ? 167.364 157.117 193.697 1.00 146.51 ? 1163 PRO A CA  1 
ATOM   8467 C C   . PRO A 1 1145 ? 166.413 158.265 193.398 1.00 146.35 ? 1163 PRO A C   1 
ATOM   8468 O O   . PRO A 1 1145 ? 165.982 158.423 192.246 1.00 149.42 ? 1163 PRO A O   1 
ATOM   8469 C CB  . PRO A 1 1145 ? 166.640 155.923 194.337 1.00 153.82 ? 1163 PRO A CB  1 
ATOM   8470 C CG  . PRO A 1 1145 ? 167.587 155.409 195.366 1.00 138.54 ? 1163 PRO A CG  1 
ATOM   8471 C CD  . PRO A 1 1145 ? 168.229 156.634 195.902 1.00 134.67 ? 1163 PRO A CD  1 
ATOM   8472 N N   . ILE A 1 1146 ? 166.102 159.092 194.396 1.00 140.70 ? 1164 ILE A N   1 
ATOM   8473 C CA  . ILE A 1 1146 ? 165.294 160.285 194.146 1.00 139.42 ? 1164 ILE A CA  1 
ATOM   8474 C C   . ILE A 1 1146 ? 166.055 161.217 193.218 1.00 141.50 ? 1164 ILE A C   1 
ATOM   8475 O O   . ILE A 1 1146 ? 165.477 161.863 192.334 1.00 150.74 ? 1164 ILE A O   1 
ATOM   8476 C CB  . ILE A 1 1146 ? 164.917 160.996 195.467 1.00 134.62 ? 1164 ILE A CB  1 
ATOM   8477 C CG1 . ILE A 1 1146 ? 164.439 160.014 196.555 1.00 141.55 ? 1164 ILE A CG1 1 
ATOM   8478 C CG2 . ILE A 1 1146 ? 163.811 162.037 195.230 1.00 145.71 ? 1164 ILE A CG2 1 
ATOM   8479 C CD1 . ILE A 1 1146 ? 164.044 160.681 197.856 1.00 148.66 ? 1164 ILE A CD1 1 
ATOM   8480 N N   . MET A 1 1147 ? 167.370 161.292 193.403 1.00 134.39 ? 1165 MET A N   1 
ATOM   8481 C CA  . MET A 1 1147 ? 168.195 162.150 192.569 1.00 140.09 ? 1165 MET A CA  1 
ATOM   8482 C C   . MET A 1 1147 ? 168.222 161.629 191.138 1.00 147.98 ? 1165 MET A C   1 
ATOM   8483 O O   . MET A 1 1147 ? 168.220 162.410 190.182 1.00 154.27 ? 1165 MET A O   1 
ATOM   8484 C CB  . MET A 1 1147 ? 169.595 162.200 193.174 1.00 138.77 ? 1165 MET A CB  1 
ATOM   8485 C CG  . MET A 1 1147 ? 170.704 162.881 192.407 1.00 146.61 ? 1165 MET A CG  1 
ATOM   8486 S SD  . MET A 1 1147 ? 170.791 164.535 193.045 1.00 153.92 ? 1165 MET A SD  1 
ATOM   8487 C CE  . MET A 1 1147 ? 171.900 164.148 194.382 1.00 135.66 ? 1165 MET A CE  1 
ATOM   8488 N N   . ARG A 1 1148 ? 168.268 160.306 190.973 1.00 144.15 ? 1166 ARG A N   1 
ATOM   8489 C CA  . ARG A 1 1148 ? 168.213 159.725 189.637 1.00 143.91 ? 1166 ARG A CA  1 
ATOM   8490 C C   . ARG A 1 1148 ? 166.876 160.011 188.972 1.00 150.89 ? 1166 ARG A C   1 
ATOM   8491 O O   . ARG A 1 1148 ? 166.825 160.261 187.762 1.00 155.96 ? 1166 ARG A O   1 
ATOM   8492 C CB  . ARG A 1 1148 ? 168.461 158.219 189.708 1.00 141.78 ? 1166 ARG A CB  1 
ATOM   8493 C CG  . ARG A 1 1148 ? 169.884 157.848 190.094 1.00 139.84 ? 1166 ARG A CG  1 
ATOM   8494 C CD  . ARG A 1 1148 ? 170.327 156.541 189.465 1.00 136.70 ? 1166 ARG A CD  1 
ATOM   8495 N NE  . ARG A 1 1148 ? 171.555 156.047 190.084 1.00 126.82 ? 1166 ARG A NE  1 
ATOM   8496 C CZ  . ARG A 1 1148 ? 171.636 155.120 191.033 1.00 124.31 ? 1166 ARG A CZ  1 
ATOM   8497 N NH1 . ARG A 1 1148 ? 170.559 154.546 191.552 1.00 124.18 ? 1166 ARG A NH1 1 
ATOM   8498 N NH2 . ARG A 1 1148 ? 172.834 154.764 191.485 1.00 126.91 ? 1166 ARG A NH2 1 
ATOM   8499 N N   . TRP A 1 1149 ? 165.785 159.973 189.741 1.00 149.78 ? 1167 TRP A N   1 
ATOM   8500 C CA  . TRP A 1 1149 ? 164.498 160.395 189.200 1.00 151.06 ? 1167 TRP A CA  1 
ATOM   8501 C C   . TRP A 1 1149 ? 164.536 161.848 188.745 1.00 155.98 ? 1167 TRP A C   1 
ATOM   8502 O O   . TRP A 1 1149 ? 164.048 162.176 187.659 1.00 163.01 ? 1167 TRP A O   1 
ATOM   8503 C CB  . TRP A 1 1149 ? 163.394 160.197 190.231 1.00 154.06 ? 1167 TRP A CB  1 
ATOM   8504 C CG  . TRP A 1 1149 ? 162.042 160.305 189.624 1.00 158.58 ? 1167 TRP A CG  1 
ATOM   8505 C CD1 . TRP A 1 1149 ? 161.402 159.375 188.864 1.00 161.61 ? 1167 TRP A CD1 1 
ATOM   8506 C CD2 . TRP A 1 1149 ? 161.169 161.432 189.702 1.00 159.75 ? 1167 TRP A CD2 1 
ATOM   8507 N NE1 . TRP A 1 1149 ? 160.172 159.848 188.475 1.00 164.75 ? 1167 TRP A NE1 1 
ATOM   8508 C CE2 . TRP A 1 1149 ? 160.006 161.111 188.978 1.00 164.84 ? 1167 TRP A CE2 1 
ATOM   8509 C CE3 . TRP A 1 1149 ? 161.255 162.681 190.321 1.00 159.19 ? 1167 TRP A CE3 1 
ATOM   8510 C CZ2 . TRP A 1 1149 ? 158.940 161.996 188.854 1.00 172.02 ? 1167 TRP A CZ2 1 
ATOM   8511 C CZ3 . TRP A 1 1149 ? 160.199 163.553 190.200 1.00 168.15 ? 1167 TRP A CZ3 1 
ATOM   8512 C CH2 . TRP A 1 1149 ? 159.056 163.209 189.471 1.00 174.01 ? 1167 TRP A CH2 1 
ATOM   8513 N N   . LEU A 1 1150 ? 165.113 162.732 189.562 1.00 153.09 ? 1168 LEU A N   1 
ATOM   8514 C CA  . LEU A 1 1150 ? 165.289 164.120 189.140 1.00 153.30 ? 1168 LEU A CA  1 
ATOM   8515 C C   . LEU A 1 1150 ? 166.133 164.231 187.878 1.00 157.47 ? 1168 LEU A C   1 
ATOM   8516 O O   . LEU A 1 1150 ? 165.882 165.112 187.050 1.00 166.09 ? 1168 LEU A O   1 
ATOM   8517 C CB  . LEU A 1 1150 ? 165.938 164.945 190.256 1.00 149.95 ? 1168 LEU A CB  1 
ATOM   8518 C CG  . LEU A 1 1150 ? 165.065 165.731 191.241 1.00 151.65 ? 1168 LEU A CG  1 
ATOM   8519 C CD1 . LEU A 1 1150 ? 164.155 166.725 190.531 1.00 164.90 ? 1168 LEU A CD1 1 
ATOM   8520 C CD2 . LEU A 1 1150 ? 164.243 164.793 192.105 1.00 149.67 ? 1168 LEU A CD2 1 
ATOM   8521 N N   . SER A 1 1151 ? 167.123 163.358 187.721 1.00 152.71 ? 1169 SER A N   1 
ATOM   8522 C CA  . SER A 1 1151 ? 167.943 163.329 186.520 1.00 155.31 ? 1169 SER A CA  1 
ATOM   8523 C C   . SER A 1 1151 ? 167.190 162.809 185.303 1.00 164.20 ? 1169 SER A C   1 
ATOM   8524 O O   . SER A 1 1151 ? 167.550 163.161 184.176 1.00 175.21 ? 1169 SER A O   1 
ATOM   8525 C CB  . SER A 1 1151 ? 169.180 162.465 186.759 1.00 154.82 ? 1169 SER A CB  1 
ATOM   8526 O OG  . SER A 1 1151 ? 169.886 162.246 185.553 1.00 156.95 ? 1169 SER A OG  1 
ATOM   8527 N N   . ARG A 1 1152 ? 166.172 161.971 185.502 1.00 166.53 ? 1170 ARG A N   1 
ATOM   8528 C CA  . ARG A 1 1152 ? 165.395 161.400 184.408 1.00 171.51 ? 1170 ARG A CA  1 
ATOM   8529 C C   . ARG A 1 1152 ? 164.139 162.196 184.072 1.00 179.21 ? 1170 ARG A C   1 
ATOM   8530 O O   . ARG A 1 1152 ? 163.418 161.816 183.142 1.00 185.53 ? 1170 ARG A O   1 
ATOM   8531 C CB  . ARG A 1 1152 ? 165.018 159.950 184.742 1.00 168.58 ? 1170 ARG A CB  1 
ATOM   8532 C CG  . ARG A 1 1152 ? 166.023 158.921 184.228 1.00 171.41 ? 1170 ARG A CG  1 
ATOM   8533 C CD  . ARG A 1 1152 ? 166.205 157.758 185.190 1.00 171.51 ? 1170 ARG A CD  1 
ATOM   8534 N NE  . ARG A 1 1152 ? 167.274 156.866 184.752 1.00 170.80 ? 1170 ARG A NE  1 
ATOM   8535 C CZ  . ARG A 1 1152 ? 168.573 157.100 184.902 1.00 165.61 ? 1170 ARG A CZ  1 
ATOM   8536 N NH1 . ARG A 1 1152 ? 169.024 158.213 185.462 1.00 165.26 ? 1170 ARG A NH1 1 
ATOM   8537 N NH2 . ARG A 1 1152 ? 169.447 156.195 184.470 1.00 153.17 ? 1170 ARG A NH2 1 
ATOM   8538 N N   . GLN A 1 1153 ? 163.865 163.292 184.783 1.00 180.94 ? 1171 GLN A N   1 
ATOM   8539 C CA  . GLN A 1 1153 ? 162.745 164.181 184.495 1.00 185.53 ? 1171 GLN A CA  1 
ATOM   8540 C C   . GLN A 1 1153 ? 163.162 165.416 183.696 1.00 195.54 ? 1171 GLN A C   1 
ATOM   8541 O O   . GLN A 1 1153 ? 162.362 166.348 183.556 1.00 200.32 ? 1171 GLN A O   1 
ATOM   8542 C CB  . GLN A 1 1153 ? 162.060 164.590 185.809 1.00 179.59 ? 1171 GLN A CB  1 
ATOM   8543 C CG  . GLN A 1 1153 ? 160.764 163.841 186.138 1.00 175.75 ? 1171 GLN A CG  1 
ATOM   8544 C CD  . GLN A 1 1153 ? 160.854 162.336 185.938 1.00 174.04 ? 1171 GLN A CD  1 
ATOM   8545 O OE1 . GLN A 1 1153 ? 161.697 161.668 186.532 1.00 171.59 ? 1171 GLN A OE1 1 
ATOM   8546 N NE2 . GLN A 1 1153 ? 159.979 161.799 185.096 1.00 177.71 ? 1171 GLN A NE2 1 
ATOM   8547 N N   . ARG A 1 1154 ? 164.379 165.428 183.143 1.00 199.41 ? 1172 ARG A N   1 
ATOM   8548 C CA  . ARG A 1 1154 ? 164.893 166.530 182.337 1.00 211.96 ? 1172 ARG A CA  1 
ATOM   8549 C C   . ARG A 1 1154 ? 165.345 166.107 180.949 1.00 221.56 ? 1172 ARG A C   1 
ATOM   8550 O O   . ARG A 1 1154 ? 165.157 166.870 179.999 1.00 228.43 ? 1172 ARG A O   1 
ATOM   8551 C CB  . ARG A 1 1154 ? 166.076 167.216 183.042 1.00 208.16 ? 1172 ARG A CB  1 
ATOM   8552 C CG  . ARG A 1 1154 ? 167.102 166.261 183.645 1.00 199.16 ? 1172 ARG A CG  1 
ATOM   8553 C CD  . ARG A 1 1154 ? 168.527 166.695 183.363 1.00 199.44 ? 1172 ARG A CD  1 
ATOM   8554 N NE  . ARG A 1 1154 ? 168.906 166.445 181.975 1.00 204.05 ? 1172 ARG A NE  1 
ATOM   8555 C CZ  . ARG A 1 1154 ? 169.408 165.308 181.506 1.00 198.79 ? 1172 ARG A CZ  1 
ATOM   8556 N NH1 . ARG A 1 1154 ? 169.564 164.240 182.276 1.00 192.49 ? 1172 ARG A NH1 1 
ATOM   8557 N NH2 . ARG A 1 1154 ? 169.759 165.235 180.226 1.00 191.34 ? 1172 ARG A NH2 1 
ATOM   8558 N N   . ASN A 1 1155 ? 165.931 164.916 180.805 1.00 220.07 ? 1173 ASN A N   1 
ATOM   8559 C CA  . ASN A 1 1155 ? 166.370 164.448 179.493 1.00 224.71 ? 1173 ASN A CA  1 
ATOM   8560 C C   . ASN A 1 1155 ? 165.215 164.301 178.510 1.00 233.95 ? 1173 ASN A C   1 
ATOM   8561 O O   . ASN A 1 1155 ? 165.434 164.403 177.298 1.00 237.19 ? 1173 ASN A O   1 
ATOM   8562 C CB  . ASN A 1 1155 ? 167.110 163.108 179.613 1.00 214.08 ? 1173 ASN A CB  1 
ATOM   8563 C CG  . ASN A 1 1155 ? 166.326 162.057 180.391 1.00 209.56 ? 1173 ASN A CG  1 
ATOM   8564 O OD1 . ASN A 1 1155 ? 165.105 162.145 180.529 1.00 215.31 ? 1173 ASN A OD1 1 
ATOM   8565 N ND2 . ASN A 1 1155 ? 167.033 161.059 180.906 1.00 184.88 ? 1173 ASN A ND2 1 
ATOM   8566 N N   . SER A 1 1156 ? 163.996 164.069 178.999 1.00 235.98 ? 1174 SER A N   1 
ATOM   8567 C CA  . SER A 1 1156 ? 162.850 163.886 178.118 1.00 242.52 ? 1174 SER A CA  1 
ATOM   8568 C C   . SER A 1 1156 ? 162.419 165.174 177.429 1.00 247.41 ? 1174 SER A C   1 
ATOM   8569 O O   . SER A 1 1156 ? 161.843 165.105 176.337 1.00 248.86 ? 1174 SER A O   1 
ATOM   8570 C CB  . SER A 1 1156 ? 161.671 163.314 178.908 1.00 239.38 ? 1174 SER A CB  1 
ATOM   8571 O OG  . SER A 1 1156 ? 161.437 164.062 180.089 1.00 231.12 ? 1174 SER A OG  1 
ATOM   8572 N N   . LEU A 1 1157 ? 162.679 166.340 178.039 1.00 247.65 ? 1175 LEU A N   1 
ATOM   8573 C CA  . LEU A 1 1157 ? 162.248 167.616 177.477 1.00 247.78 ? 1175 LEU A CA  1 
ATOM   8574 C C   . LEU A 1 1157 ? 163.287 168.723 177.632 1.00 246.63 ? 1175 LEU A C   1 
ATOM   8575 O O   . LEU A 1 1157 ? 162.930 169.901 177.501 1.00 245.44 ? 1175 LEU A O   1 
ATOM   8576 C CB  . LEU A 1 1157 ? 160.916 168.056 178.116 1.00 244.92 ? 1175 LEU A CB  1 
ATOM   8577 C CG  . LEU A 1 1157 ? 160.908 168.729 179.496 1.00 238.46 ? 1175 LEU A CG  1 
ATOM   8578 C CD1 . LEU A 1 1157 ? 159.479 169.046 179.910 1.00 235.40 ? 1175 LEU A CD1 1 
ATOM   8579 C CD2 . LEU A 1 1157 ? 161.591 167.869 180.549 1.00 234.33 ? 1175 LEU A CD2 1 
ATOM   8580 N N   . GLY A 1 1158 ? 164.551 168.394 177.897 1.00 245.09 ? 1176 GLY A N   1 
ATOM   8581 C CA  . GLY A 1 1158 ? 165.575 169.410 178.055 1.00 244.98 ? 1176 GLY A CA  1 
ATOM   8582 C C   . GLY A 1 1158 ? 165.673 169.905 179.482 1.00 242.20 ? 1176 GLY A C   1 
ATOM   8583 O O   . GLY A 1 1158 ? 166.322 169.277 180.324 1.00 233.98 ? 1176 GLY A O   1 
ATOM   8584 N N   . GLY A 1 1159 ? 165.031 171.035 179.763 1.00 244.33 ? 1177 GLY A N   1 
ATOM   8585 C CA  . GLY A 1 1159 ? 165.000 171.573 181.107 1.00 235.78 ? 1177 GLY A CA  1 
ATOM   8586 C C   . GLY A 1 1159 ? 163.910 170.918 181.928 1.00 230.65 ? 1177 GLY A C   1 
ATOM   8587 O O   . GLY A 1 1159 ? 163.880 169.690 182.049 1.00 225.11 ? 1177 GLY A O   1 
ATOM   8588 N N   . PHE A 1 1160 ? 163.017 171.724 182.500 1.00 233.06 ? 1178 PHE A N   1 
ATOM   8589 C CA  . PHE A 1 1160 ? 161.905 171.230 183.299 1.00 233.82 ? 1178 PHE A CA  1 
ATOM   8590 C C   . PHE A 1 1160 ? 160.623 171.936 182.883 1.00 242.95 ? 1178 PHE A C   1 
ATOM   8591 O O   . PHE A 1 1160 ? 160.629 173.122 182.542 1.00 245.58 ? 1178 PHE A O   1 
ATOM   8592 C CB  . PHE A 1 1160 ? 162.160 171.441 184.795 1.00 223.82 ? 1178 PHE A CB  1 
ATOM   8593 C CG  . PHE A 1 1160 ? 163.215 170.537 185.360 1.00 213.72 ? 1178 PHE A CG  1 
ATOM   8594 C CD1 . PHE A 1 1160 ? 162.923 169.220 185.671 1.00 209.21 ? 1178 PHE A CD1 1 
ATOM   8595 C CD2 . PHE A 1 1160 ? 164.500 171.003 185.577 1.00 210.52 ? 1178 PHE A CD2 1 
ATOM   8596 C CE1 . PHE A 1 1160 ? 163.894 168.386 186.190 1.00 204.42 ? 1178 PHE A CE1 1 
ATOM   8597 C CE2 . PHE A 1 1160 ? 165.475 170.172 186.096 1.00 206.30 ? 1178 PHE A CE2 1 
ATOM   8598 C CZ  . PHE A 1 1160 ? 165.171 168.863 186.403 1.00 202.02 ? 1178 PHE A CZ  1 
ATOM   8599 N N   . ALA A 1 1161 ? 159.523 171.189 182.913 1.00 246.01 ? 1179 ALA A N   1 
ATOM   8600 C CA  . ALA A 1 1161 ? 158.226 171.747 182.561 1.00 243.66 ? 1179 ALA A CA  1 
ATOM   8601 C C   . ALA A 1 1161 ? 157.809 172.807 183.574 1.00 242.78 ? 1179 ALA A C   1 
ATOM   8602 O O   . ALA A 1 1161 ? 158.148 172.734 184.758 1.00 244.56 ? 1179 ALA A O   1 
ATOM   8603 C CB  . ALA A 1 1161 ? 157.169 170.644 182.497 1.00 240.04 ? 1179 ALA A CB  1 
ATOM   8604 N N   . SER A 1 1162 ? 157.063 173.802 183.090 1.00 241.04 ? 1180 SER A N   1 
ATOM   8605 C CA  . SER A 1 1162 ? 156.593 174.899 183.929 1.00 241.57 ? 1180 SER A CA  1 
ATOM   8606 C C   . SER A 1 1162 ? 157.772 175.657 184.530 1.00 241.85 ? 1180 SER A C   1 
ATOM   8607 O O   . SER A 1 1162 ? 158.893 175.566 184.018 1.00 240.12 ? 1180 SER A O   1 
ATOM   8608 C CB  . SER A 1 1162 ? 155.669 174.365 185.029 1.00 238.90 ? 1180 SER A CB  1 
ATOM   8609 O OG  . SER A 1 1162 ? 156.401 174.052 186.201 1.00 237.35 ? 1180 SER A OG  1 
ATOM   8610 N N   . THR A 1 1163 ? 157.525 176.417 185.602 1.00 242.11 ? 1181 THR A N   1 
ATOM   8611 C CA  . THR A 1 1163 ? 158.571 177.143 186.316 1.00 239.51 ? 1181 THR A CA  1 
ATOM   8612 C C   . THR A 1 1163 ? 158.540 176.950 187.824 1.00 234.26 ? 1181 THR A C   1 
ATOM   8613 O O   . THR A 1 1163 ? 159.555 177.224 188.475 1.00 229.22 ? 1181 THR A O   1 
ATOM   8614 C CB  . THR A 1 1163 ? 158.475 178.648 186.021 1.00 243.11 ? 1181 THR A CB  1 
ATOM   8615 O OG1 . THR A 1 1163 ? 157.199 179.142 186.448 1.00 244.85 ? 1181 THR A OG1 1 
ATOM   8616 C CG2 . THR A 1 1163 ? 158.646 178.917 184.532 1.00 238.93 ? 1181 THR A CG2 1 
ATOM   8617 N N   . GLN A 1 1164 ? 157.425 176.497 188.402 1.00 235.14 ? 1182 GLN A N   1 
ATOM   8618 C CA  . GLN A 1 1164 ? 157.363 176.333 189.852 1.00 229.81 ? 1182 GLN A CA  1 
ATOM   8619 C C   . GLN A 1 1164 ? 158.291 175.227 190.340 1.00 222.80 ? 1182 GLN A C   1 
ATOM   8620 O O   . GLN A 1 1164 ? 158.893 175.357 191.412 1.00 213.00 ? 1182 GLN A O   1 
ATOM   8621 C CB  . GLN A 1 1164 ? 155.923 176.056 190.304 1.00 231.03 ? 1182 GLN A CB  1 
ATOM   8622 C CG  . GLN A 1 1164 ? 155.195 174.906 189.588 1.00 230.77 ? 1182 GLN A CG  1 
ATOM   8623 C CD  . GLN A 1 1164 ? 154.298 175.371 188.451 1.00 235.84 ? 1182 GLN A CD  1 
ATOM   8624 O OE1 . GLN A 1 1164 ? 154.459 176.472 187.922 1.00 238.35 ? 1182 GLN A OE1 1 
ATOM   8625 N NE2 . GLN A 1 1164 ? 153.345 174.528 188.071 1.00 235.17 ? 1182 GLN A NE2 1 
ATOM   8626 N N   . ASP A 1 1165 ? 158.429 174.145 189.574 1.00 224.36 ? 1183 ASP A N   1 
ATOM   8627 C CA  . ASP A 1 1165 ? 159.222 172.995 189.996 1.00 219.72 ? 1183 ASP A CA  1 
ATOM   8628 C C   . ASP A 1 1165 ? 160.692 173.110 189.619 1.00 210.18 ? 1183 ASP A C   1 
ATOM   8629 O O   . ASP A 1 1165 ? 161.536 172.471 190.267 1.00 206.33 ? 1183 ASP A O   1 
ATOM   8630 C CB  . ASP A 1 1165 ? 158.657 171.704 189.393 1.00 217.91 ? 1183 ASP A CB  1 
ATOM   8631 C CG  . ASP A 1 1165 ? 158.638 171.723 187.876 1.00 223.39 ? 1183 ASP A CG  1 
ATOM   8632 O OD1 . ASP A 1 1165 ? 159.691 171.447 187.263 1.00 222.81 ? 1183 ASP A OD1 1 
ATOM   8633 O OD2 . ASP A 1 1165 ? 157.567 172.008 187.300 1.00 228.23 ? 1183 ASP A OD2 1 
ATOM   8634 N N   . THR A 1 1166 ? 161.010 173.893 188.585 1.00 209.24 ? 1184 THR A N   1 
ATOM   8635 C CA  . THR A 1 1166 ? 162.397 174.061 188.169 1.00 205.54 ? 1184 THR A CA  1 
ATOM   8636 C C   . THR A 1 1166 ? 163.233 174.659 189.290 1.00 199.74 ? 1184 THR A C   1 
ATOM   8637 O O   . THR A 1 1166 ? 164.380 174.249 189.505 1.00 200.26 ? 1184 THR A O   1 
ATOM   8638 C CB  . THR A 1 1166 ? 162.460 174.946 186.922 1.00 209.98 ? 1184 THR A CB  1 
ATOM   8639 O OG1 . THR A 1 1166 ? 161.452 174.535 185.990 1.00 218.17 ? 1184 THR A OG1 1 
ATOM   8640 C CG2 . THR A 1 1166 ? 163.830 174.874 186.262 1.00 206.98 ? 1184 THR A CG2 1 
ATOM   8641 N N   . THR A 1 1167 ? 162.661 175.607 190.034 1.00 200.60 ? 1185 THR A N   1 
ATOM   8642 C CA  . THR A 1 1167 ? 163.396 176.242 191.125 1.00 200.54 ? 1185 THR A CA  1 
ATOM   8643 C C   . THR A 1 1167 ? 163.797 175.223 192.183 1.00 193.93 ? 1185 THR A C   1 
ATOM   8644 O O   . THR A 1 1167 ? 164.970 175.144 192.564 1.00 192.79 ? 1185 THR A O   1 
ATOM   8645 C CB  . THR A 1 1167 ? 162.574 177.363 191.770 1.00 204.67 ? 1185 THR A CB  1 
ATOM   8646 O OG1 . THR A 1 1167 ? 161.634 176.800 192.696 1.00 201.99 ? 1185 THR A OG1 1 
ATOM   8647 C CG2 . THR A 1 1167 ? 161.865 178.252 190.742 1.00 210.88 ? 1185 THR A CG2 1 
ATOM   8648 N N   . VAL A 1 1168 ? 162.842 174.420 192.656 1.00 189.00 ? 1186 VAL A N   1 
ATOM   8649 C CA  . VAL A 1 1168 ? 163.158 173.473 193.724 1.00 181.42 ? 1186 VAL A CA  1 
ATOM   8650 C C   . VAL A 1 1168 ? 164.083 172.371 193.218 1.00 179.29 ? 1186 VAL A C   1 
ATOM   8651 O O   . VAL A 1 1168 ? 164.988 171.935 193.945 1.00 175.90 ? 1186 VAL A O   1 
ATOM   8652 C CB  . VAL A 1 1168 ? 161.878 172.888 194.362 1.00 180.40 ? 1186 VAL A CB  1 
ATOM   8653 C CG1 . VAL A 1 1168 ? 161.186 173.945 195.210 1.00 178.80 ? 1186 VAL A CG1 1 
ATOM   8654 C CG2 . VAL A 1 1168 ? 160.910 172.306 193.328 1.00 188.71 ? 1186 VAL A CG2 1 
ATOM   8655 N N   . ALA A 1 1169 ? 163.897 171.909 191.977 1.00 181.89 ? 1187 ALA A N   1 
ATOM   8656 C CA  . ALA A 1 1169 ? 164.763 170.855 191.457 1.00 176.29 ? 1187 ALA A CA  1 
ATOM   8657 C C   . ALA A 1 1169 ? 166.203 171.340 191.331 1.00 171.48 ? 1187 ALA A C   1 
ATOM   8658 O O   . ALA A 1 1169 ? 167.143 170.665 191.778 1.00 170.28 ? 1187 ALA A O   1 
ATOM   8659 C CB  . ALA A 1 1169 ? 164.239 170.367 190.107 1.00 185.85 ? 1187 ALA A CB  1 
ATOM   8660 N N   . LEU A 1 1170 ? 166.396 172.521 190.740 1.00 173.45 ? 1188 LEU A N   1 
ATOM   8661 C CA  . LEU A 1 1170 ? 167.746 173.045 190.606 1.00 169.37 ? 1188 LEU A CA  1 
ATOM   8662 C C   . LEU A 1 1170 ? 168.336 173.415 191.959 1.00 169.44 ? 1188 LEU A C   1 
ATOM   8663 O O   . LEU A 1 1170 ? 169.551 173.314 192.144 1.00 171.11 ? 1188 LEU A O   1 
ATOM   8664 C CB  . LEU A 1 1170 ? 167.755 174.252 189.662 1.00 174.83 ? 1188 LEU A CB  1 
ATOM   8665 C CG  . LEU A 1 1170 ? 167.959 174.006 188.157 1.00 180.70 ? 1188 LEU A CG  1 
ATOM   8666 C CD1 . LEU A 1 1170 ? 169.270 173.297 187.849 1.00 179.98 ? 1188 LEU A CD1 1 
ATOM   8667 C CD2 . LEU A 1 1170 ? 166.800 173.210 187.578 1.00 189.48 ? 1188 LEU A CD2 1 
ATOM   8668 N N   . LYS A 1 1171 ? 167.503 173.821 192.922 1.00 169.23 ? 1189 LYS A N   1 
ATOM   8669 C CA  . LYS A 1 1171 ? 168.013 174.083 194.263 1.00 164.06 ? 1189 LYS A CA  1 
ATOM   8670 C C   . LYS A 1 1171 ? 168.537 172.809 194.908 1.00 160.79 ? 1189 LYS A C   1 
ATOM   8671 O O   . LYS A 1 1171 ? 169.603 172.818 195.534 1.00 160.33 ? 1189 LYS A O   1 
ATOM   8672 C CB  . LYS A 1 1171 ? 166.919 174.701 195.130 1.00 165.23 ? 1189 LYS A CB  1 
ATOM   8673 C CG  . LYS A 1 1171 ? 167.419 175.234 196.464 1.00 159.42 ? 1189 LYS A CG  1 
ATOM   8674 C CD  . LYS A 1 1171 ? 166.315 175.940 197.231 1.00 169.32 ? 1189 LYS A CD  1 
ATOM   8675 C CE  . LYS A 1 1171 ? 166.821 176.480 198.557 1.00 170.33 ? 1189 LYS A CE  1 
ATOM   8676 N NZ  . LYS A 1 1171 ? 165.866 177.440 199.175 1.00 179.37 ? 1189 LYS A NZ  1 
ATOM   8677 N N   . ALA A 1 1172 ? 167.800 171.705 194.771 1.00 163.71 ? 1190 ALA A N   1 
ATOM   8678 C CA  . ALA A 1 1172 ? 168.267 170.440 195.328 1.00 160.02 ? 1190 ALA A CA  1 
ATOM   8679 C C   . ALA A 1 1172 ? 169.561 169.993 194.663 1.00 154.18 ? 1190 ALA A C   1 
ATOM   8680 O O   . ALA A 1 1172 ? 170.498 169.552 195.343 1.00 154.07 ? 1190 ALA A O   1 
ATOM   8681 C CB  . ALA A 1 1172 ? 167.188 169.370 195.176 1.00 160.74 ? 1190 ALA A CB  1 
ATOM   8682 N N   . LEU A 1 1173 ? 169.639 170.112 193.336 1.00 152.73 ? 1191 LEU A N   1 
ATOM   8683 C CA  . LEU A 1 1173 ? 170.862 169.720 192.643 1.00 151.77 ? 1191 LEU A CA  1 
ATOM   8684 C C   . LEU A 1 1173 ? 172.042 170.603 193.041 1.00 153.32 ? 1191 LEU A C   1 
ATOM   8685 O O   . LEU A 1 1173 ? 173.161 170.104 193.219 1.00 151.02 ? 1191 LEU A O   1 
ATOM   8686 C CB  . LEU A 1 1173 ? 170.641 169.767 191.132 1.00 153.51 ? 1191 LEU A CB  1 
ATOM   8687 C CG  . LEU A 1 1173 ? 169.783 168.648 190.531 1.00 148.79 ? 1191 LEU A CG  1 
ATOM   8688 C CD1 . LEU A 1 1173 ? 169.431 168.977 189.093 1.00 160.09 ? 1191 LEU A CD1 1 
ATOM   8689 C CD2 . LEU A 1 1173 ? 170.492 167.305 190.595 1.00 143.21 ? 1191 LEU A CD2 1 
ATOM   8690 N N   . SER A 1 1174 ? 171.814 171.907 193.200 1.00 157.87 ? 1192 SER A N   1 
ATOM   8691 C CA  . SER A 1 1174 ? 172.881 172.798 193.636 1.00 159.30 ? 1192 SER A CA  1 
ATOM   8692 C C   . SER A 1 1174 ? 173.330 172.482 195.055 1.00 156.96 ? 1192 SER A C   1 
ATOM   8693 O O   . SER A 1 1174 ? 174.528 172.542 195.349 1.00 160.50 ? 1192 SER A O   1 
ATOM   8694 C CB  . SER A 1 1174 ? 172.417 174.250 193.540 1.00 167.35 ? 1192 SER A CB  1 
ATOM   8695 O OG  . SER A 1 1174 ? 171.525 174.568 194.594 1.00 166.43 ? 1192 SER A OG  1 
ATOM   8696 N N   . GLU A 1 1175 ? 172.391 172.156 195.947 1.00 153.06 ? 1193 GLU A N   1 
ATOM   8697 C CA  . GLU A 1 1175 ? 172.767 171.766 197.303 1.00 148.69 ? 1193 GLU A CA  1 
ATOM   8698 C C   . GLU A 1 1175 ? 173.603 170.496 197.290 1.00 148.57 ? 1193 GLU A C   1 
ATOM   8699 O O   . GLU A 1 1175 ? 174.578 170.376 198.043 1.00 152.93 ? 1193 GLU A O   1 
ATOM   8700 C CB  . GLU A 1 1175 ? 171.520 171.570 198.167 1.00 147.08 ? 1193 GLU A CB  1 
ATOM   8701 C CG  . GLU A 1 1175 ? 171.172 172.771 199.038 1.00 152.96 ? 1193 GLU A CG  1 
ATOM   8702 C CD  . GLU A 1 1175 ? 172.137 172.970 200.193 1.00 152.46 ? 1193 GLU A CD  1 
ATOM   8703 O OE1 . GLU A 1 1175 ? 172.726 171.976 200.667 1.00 152.46 ? 1193 GLU A OE1 1 
ATOM   8704 O OE2 . GLU A 1 1175 ? 172.308 174.128 200.627 1.00 153.60 ? 1193 GLU A OE2 1 
ATOM   8705 N N   . PHE A 1 1176 ? 173.232 169.537 196.439 1.00 145.31 ? 1194 PHE A N   1 
ATOM   8706 C CA  . PHE A 1 1176 ? 174.045 168.337 196.277 1.00 141.31 ? 1194 PHE A CA  1 
ATOM   8707 C C   . PHE A 1 1176 ? 175.452 168.678 195.815 1.00 143.41 ? 1194 PHE A C   1 
ATOM   8708 O O   . PHE A 1 1176 ? 176.433 168.137 196.336 1.00 141.81 ? 1194 PHE A O   1 
ATOM   8709 C CB  . PHE A 1 1176 ? 173.409 167.406 195.260 1.00 140.25 ? 1194 PHE A CB  1 
ATOM   8710 C CG  . PHE A 1 1176 ? 174.316 166.299 194.820 1.00 133.67 ? 1194 PHE A CG  1 
ATOM   8711 C CD1 . PHE A 1 1176 ? 174.761 165.353 195.722 1.00 124.83 ? 1194 PHE A CD1 1 
ATOM   8712 C CD2 . PHE A 1 1176 ? 174.729 166.210 193.505 1.00 140.88 ? 1194 PHE A CD2 1 
ATOM   8713 C CE1 . PHE A 1 1176 ? 175.587 164.325 195.314 1.00 123.09 ? 1194 PHE A CE1 1 
ATOM   8714 C CE2 . PHE A 1 1176 ? 175.561 165.189 193.096 1.00 140.97 ? 1194 PHE A CE2 1 
ATOM   8715 C CZ  . PHE A 1 1176 ? 175.992 164.248 194.004 1.00 133.35 ? 1194 PHE A CZ  1 
ATOM   8716 N N   . ALA A 1 1177 ? 175.567 169.554 194.814 1.00 148.99 ? 1195 ALA A N   1 
ATOM   8717 C CA  . ALA A 1 1177 ? 176.886 169.942 194.330 1.00 151.57 ? 1195 ALA A CA  1 
ATOM   8718 C C   . ALA A 1 1177 ? 177.694 170.630 195.421 1.00 153.75 ? 1195 ALA A C   1 
ATOM   8719 O O   . ALA A 1 1177 ? 178.901 170.394 195.540 1.00 153.19 ? 1195 ALA A O   1 
ATOM   8720 C CB  . ALA A 1 1177 ? 176.750 170.855 193.113 1.00 161.82 ? 1195 ALA A CB  1 
ATOM   8721 N N   . ALA A 1 1178 ? 177.042 171.459 196.235 1.00 156.89 ? 1196 ALA A N   1 
ATOM   8722 C CA  . ALA A 1 1178 ? 177.725 172.183 197.297 1.00 156.75 ? 1196 ALA A CA  1 
ATOM   8723 C C   . ALA A 1 1178 ? 178.175 171.277 198.433 1.00 151.68 ? 1196 ALA A C   1 
ATOM   8724 O O   . ALA A 1 1178 ? 179.211 171.551 199.048 1.00 157.48 ? 1196 ALA A O   1 
ATOM   8725 C CB  . ALA A 1 1178 ? 176.815 173.277 197.857 1.00 157.56 ? 1196 ALA A CB  1 
ATOM   8726 N N   . LEU A 1 1179 ? 177.424 170.215 198.730 1.00 141.93 ? 1197 LEU A N   1 
ATOM   8727 C CA  . LEU A 1 1179 ? 177.799 169.349 199.845 1.00 136.89 ? 1197 LEU A CA  1 
ATOM   8728 C C   . LEU A 1 1179 ? 179.119 168.631 199.586 1.00 138.97 ? 1197 LEU A C   1 
ATOM   8729 O O   . LEU A 1 1179 ? 179.862 168.352 200.534 1.00 141.15 ? 1197 LEU A O   1 
ATOM   8730 C CB  . LEU A 1 1179 ? 176.694 168.326 200.123 1.00 133.66 ? 1197 LEU A CB  1 
ATOM   8731 C CG  . LEU A 1 1179 ? 175.676 168.602 201.233 1.00 138.27 ? 1197 LEU A CG  1 
ATOM   8732 C CD1 . LEU A 1 1179 ? 174.657 167.476 201.273 1.00 133.61 ? 1197 LEU A CD1 1 
ATOM   8733 C CD2 . LEU A 1 1179 ? 176.338 168.749 202.597 1.00 138.45 ? 1197 LEU A CD2 1 
ATOM   8734 N N   . MET A 1 1180 ? 179.424 168.323 198.326 1.00 141.48 ? 1198 MET A N   1 
ATOM   8735 C CA  . MET A 1 1180 ? 180.658 167.652 197.909 1.00 143.79 ? 1198 MET A CA  1 
ATOM   8736 C C   . MET A 1 1180 ? 181.300 168.398 196.746 1.00 153.68 ? 1198 MET A C   1 
ATOM   8737 O O   . MET A 1 1180 ? 181.611 167.828 195.699 1.00 150.09 ? 1198 MET A O   1 
ATOM   8738 C CB  . MET A 1 1180 ? 180.420 166.193 197.534 1.00 130.02 ? 1198 MET A CB  1 
ATOM   8739 C CG  . MET A 1 1180 ? 179.944 165.317 198.688 1.00 131.16 ? 1198 MET A CG  1 
ATOM   8740 S SD  . MET A 1 1180 ? 178.576 164.222 198.279 1.00 116.69 ? 1198 MET A SD  1 
ATOM   8741 C CE  . MET A 1 1180 ? 177.311 165.420 197.899 1.00 129.04 ? 1198 MET A CE  1 
ATOM   8742 N N   . ASN A 1 1181 ? 181.506 169.703 196.923 1.00 163.17 ? 1199 ASN A N   1 
ATOM   8743 C CA  . ASN A 1 1181 ? 182.042 170.569 195.875 1.00 169.71 ? 1199 ASN A CA  1 
ATOM   8744 C C   . ASN A 1 1181 ? 183.572 170.485 195.731 1.00 176.68 ? 1199 ASN A C   1 
ATOM   8745 O O   . ASN A 1 1181 ? 184.171 171.414 195.176 1.00 181.74 ? 1199 ASN A O   1 
ATOM   8746 C CB  . ASN A 1 1181 ? 181.620 172.028 196.118 1.00 172.16 ? 1199 ASN A CB  1 
ATOM   8747 C CG  . ASN A 1 1181 ? 182.025 172.557 197.495 1.00 176.34 ? 1199 ASN A CG  1 
ATOM   8748 O OD1 . ASN A 1 1181 ? 183.095 172.242 198.016 1.00 174.91 ? 1199 ASN A OD1 1 
ATOM   8749 N ND2 . ASN A 1 1181 ? 181.157 173.371 198.086 1.00 176.37 ? 1199 ASN A ND2 1 
ATOM   8750 N N   . THR A 1 1182 ? 184.217 169.423 196.216 1.00 176.29 ? 1200 THR A N   1 
ATOM   8751 C CA  . THR A 1 1182 ? 185.659 169.284 196.058 1.00 178.98 ? 1200 THR A CA  1 
ATOM   8752 C C   . THR A 1 1182 ? 186.022 169.193 194.580 1.00 180.77 ? 1200 THR A C   1 
ATOM   8753 O O   . THR A 1 1182 ? 185.454 168.386 193.838 1.00 178.62 ? 1200 THR A O   1 
ATOM   8754 C CB  . THR A 1 1182 ? 186.157 168.044 196.798 1.00 168.35 ? 1200 THR A CB  1 
ATOM   8755 O OG1 . THR A 1 1182 ? 185.371 166.908 196.417 1.00 161.54 ? 1200 THR A OG1 1 
ATOM   8756 C CG2 . THR A 1 1182 ? 186.058 168.243 198.303 1.00 167.31 ? 1200 THR A CG2 1 
ATOM   8757 N N   . GLU A 1 1183 ? 186.974 170.024 194.157 1.00 180.96 ? 1201 GLU A N   1 
ATOM   8758 C CA  . GLU A 1 1183 ? 187.354 170.109 192.751 1.00 177.80 ? 1201 GLU A CA  1 
ATOM   8759 C C   . GLU A 1 1183 ? 188.348 169.034 192.323 1.00 171.58 ? 1201 GLU A C   1 
ATOM   8760 O O   . GLU A 1 1183 ? 188.517 168.830 191.116 1.00 166.97 ? 1201 GLU A O   1 
ATOM   8761 C CB  . GLU A 1 1183 ? 187.922 171.507 192.451 1.00 174.26 ? 1201 GLU A CB  1 
ATOM   8762 C CG  . GLU A 1 1183 ? 189.420 171.727 192.728 1.00 174.39 ? 1201 GLU A CG  1 
ATOM   8763 C CD  . GLU A 1 1183 ? 189.826 171.371 194.146 1.00 175.25 ? 1201 GLU A CD  1 
ATOM   8764 O OE1 . GLU A 1 1183 ? 189.027 171.615 195.073 1.00 174.13 ? 1201 GLU A OE1 1 
ATOM   8765 O OE2 . GLU A 1 1183 ? 190.946 170.853 194.333 1.00 172.78 ? 1201 GLU A OE2 1 
ATOM   8766 N N   . ARG A 1 1184 ? 188.997 168.349 193.263 1.00 169.81 ? 1202 ARG A N   1 
ATOM   8767 C CA  . ARG A 1 1184 ? 189.982 167.317 192.967 1.00 157.90 ? 1202 ARG A CA  1 
ATOM   8768 C C   . ARG A 1 1184 ? 189.412 165.949 193.313 1.00 149.32 ? 1202 ARG A C   1 
ATOM   8769 O O   . ARG A 1 1184 ? 188.749 165.785 194.342 1.00 151.84 ? 1202 ARG A O   1 
ATOM   8770 C CB  . ARG A 1 1184 ? 191.275 167.553 193.750 1.00 161.03 ? 1202 ARG A CB  1 
ATOM   8771 C CG  . ARG A 1 1184 ? 192.458 166.737 193.254 1.00 156.37 ? 1202 ARG A CG  1 
ATOM   8772 C CD  . ARG A 1 1184 ? 193.690 166.977 194.110 1.00 168.08 ? 1202 ARG A CD  1 
ATOM   8773 N NE  . ARG A 1 1184 ? 193.554 166.390 195.441 1.00 168.66 ? 1202 ARG A NE  1 
ATOM   8774 C CZ  . ARG A 1 1184 ? 193.901 165.153 195.781 1.00 168.37 ? 1202 ARG A CZ  1 
ATOM   8775 N NH1 . ARG A 1 1184 ? 194.397 164.295 194.900 1.00 168.09 ? 1202 ARG A NH1 1 
ATOM   8776 N NH2 . ARG A 1 1184 ? 193.740 164.762 197.042 1.00 160.75 ? 1202 ARG A NH2 1 
ATOM   8777 N N   . THR A 1 1185 ? 189.671 164.974 192.444 1.00 135.72 ? 1203 THR A N   1 
ATOM   8778 C CA  . THR A 1 1185 ? 189.209 163.606 192.637 1.00 125.99 ? 1203 THR A CA  1 
ATOM   8779 C C   . THR A 1 1185 ? 190.309 162.648 192.212 1.00 120.00 ? 1203 THR A C   1 
ATOM   8780 O O   . THR A 1 1185 ? 190.851 162.774 191.111 1.00 121.97 ? 1203 THR A O   1 
ATOM   8781 C CB  . THR A 1 1185 ? 187.931 163.338 191.832 1.00 119.98 ? 1203 THR A CB  1 
ATOM   8782 O OG1 . THR A 1 1185 ? 187.018 164.428 192.004 1.00 123.93 ? 1203 THR A OG1 1 
ATOM   8783 C CG2 . THR A 1 1185 ? 187.268 162.049 192.290 1.00 115.03 ? 1203 THR A CG2 1 
ATOM   8784 N N   . ASN A 1 1186 ? 190.654 161.717 193.098 1.00 116.77 ? 1204 ASN A N   1 
ATOM   8785 C CA  . ASN A 1 1186 ? 191.613 160.656 192.807 1.00 119.29 ? 1204 ASN A CA  1 
ATOM   8786 C C   . ASN A 1 1186 ? 191.151 159.345 193.427 1.00 115.73 ? 1204 ASN A C   1 
ATOM   8787 O O   . ASN A 1 1186 ? 191.951 158.579 193.974 1.00 117.31 ? 1204 ASN A O   1 
ATOM   8788 C CB  . ASN A 1 1186 ? 193.008 161.028 193.306 1.00 128.18 ? 1204 ASN A CB  1 
ATOM   8789 C CG  . ASN A 1 1186 ? 194.105 160.308 192.552 1.00 129.13 ? 1204 ASN A CG  1 
ATOM   8790 O OD1 . ASN A 1 1186 ? 194.225 160.441 191.335 1.00 128.36 ? 1204 ASN A OD1 1 
ATOM   8791 N ND2 . ASN A 1 1186 ? 194.914 159.539 193.272 1.00 127.49 ? 1204 ASN A ND2 1 
ATOM   8792 N N   . ILE A 1 1187 ? 189.857 159.064 193.344 1.00 103.32 ? 1205 ILE A N   1 
ATOM   8793 C CA  . ILE A 1 1187 ? 189.269 157.963 194.100 1.00 95.50  ? 1205 ILE A CA  1 
ATOM   8794 C C   . ILE A 1 1187 ? 189.616 156.642 193.429 1.00 100.93 ? 1205 ILE A C   1 
ATOM   8795 O O   . ILE A 1 1187 ? 189.607 156.531 192.198 1.00 113.65 ? 1205 ILE A O   1 
ATOM   8796 C CB  . ILE A 1 1187 ? 187.747 158.159 194.241 1.00 87.62  ? 1205 ILE A CB  1 
ATOM   8797 C CG1 . ILE A 1 1187 ? 187.495 159.083 195.437 1.00 108.41 ? 1205 ILE A CG1 1 
ATOM   8798 C CG2 . ILE A 1 1187 ? 186.991 156.807 194.391 1.00 85.65  ? 1205 ILE A CG2 1 
ATOM   8799 C CD1 . ILE A 1 1187 ? 186.065 159.538 195.639 1.00 112.29 ? 1205 ILE A CD1 1 
ATOM   8800 N N   . GLN A 1 1188 ? 189.925 155.639 194.249 1.00 99.73  ? 1206 GLN A N   1 
ATOM   8801 C CA  . GLN A 1 1188 ? 190.069 154.254 193.824 1.00 102.50 ? 1206 GLN A CA  1 
ATOM   8802 C C   . GLN A 1 1188 ? 189.056 153.421 194.596 1.00 99.84  ? 1206 GLN A C   1 
ATOM   8803 O O   . GLN A 1 1188 ? 189.078 153.402 195.832 1.00 110.75 ? 1206 GLN A O   1 
ATOM   8804 C CB  . GLN A 1 1188 ? 191.488 153.749 194.076 1.00 107.55 ? 1206 GLN A CB  1 
ATOM   8805 C CG  . GLN A 1 1188 ? 191.769 152.382 193.478 1.00 113.50 ? 1206 GLN A CG  1 
ATOM   8806 C CD  . GLN A 1 1188 ? 193.249 152.062 193.420 1.00 131.03 ? 1206 GLN A CD  1 
ATOM   8807 O OE1 . GLN A 1 1188 ? 194.085 152.839 193.881 1.00 140.10 ? 1206 GLN A OE1 1 
ATOM   8808 N NE2 . GLN A 1 1188 ? 193.581 150.910 192.851 1.00 131.03 ? 1206 GLN A NE2 1 
ATOM   8809 N N   . VAL A 1 1189 ? 188.175 152.742 193.867 1.00 91.37  ? 1207 VAL A N   1 
ATOM   8810 C CA  . VAL A 1 1189 ? 187.122 151.911 194.438 1.00 89.68  ? 1207 VAL A CA  1 
ATOM   8811 C C   . VAL A 1 1189 ? 187.508 150.460 194.211 1.00 93.99  ? 1207 VAL A C   1 
ATOM   8812 O O   . VAL A 1 1189 ? 187.629 150.019 193.062 1.00 105.11 ? 1207 VAL A O   1 
ATOM   8813 C CB  . VAL A 1 1189 ? 185.755 152.217 193.806 1.00 86.22  ? 1207 VAL A CB  1 
ATOM   8814 C CG1 . VAL A 1 1189 ? 184.722 151.183 194.234 1.00 93.23  ? 1207 VAL A CG1 1 
ATOM   8815 C CG2 . VAL A 1 1189 ? 185.303 153.618 194.168 1.00 87.53  ? 1207 VAL A CG2 1 
ATOM   8816 N N   . THR A 1 1190 ? 187.690 149.717 195.300 1.00 95.40  ? 1208 THR A N   1 
ATOM   8817 C CA  . THR A 1 1190 ? 188.006 148.296 195.262 1.00 103.42 ? 1208 THR A CA  1 
ATOM   8818 C C   . THR A 1 1190 ? 186.780 147.522 195.720 1.00 105.22 ? 1208 THR A C   1 
ATOM   8819 O O   . THR A 1 1190 ? 186.287 147.739 196.833 1.00 116.43 ? 1208 THR A O   1 
ATOM   8820 C CB  . THR A 1 1190 ? 189.206 147.977 196.154 1.00 111.75 ? 1208 THR A CB  1 
ATOM   8821 O OG1 . THR A 1 1190 ? 190.202 148.996 196.002 1.00 119.67 ? 1208 THR A OG1 1 
ATOM   8822 C CG2 . THR A 1 1190 ? 189.804 146.628 195.787 1.00 108.76 ? 1208 THR A CG2 1 
ATOM   8823 N N   . VAL A 1 1191 ? 186.295 146.629 194.867 1.00 100.55 ? 1209 VAL A N   1 
ATOM   8824 C CA  . VAL A 1 1191 ? 185.151 145.776 195.159 1.00 102.56 ? 1209 VAL A CA  1 
ATOM   8825 C C   . VAL A 1 1191 ? 185.701 144.388 195.439 1.00 111.34 ? 1209 VAL A C   1 
ATOM   8826 O O   . VAL A 1 1191 ? 186.385 143.800 194.589 1.00 118.92 ? 1209 VAL A O   1 
ATOM   8827 C CB  . VAL A 1 1191 ? 184.144 145.754 194.002 1.00 100.03 ? 1209 VAL A CB  1 
ATOM   8828 C CG1 . VAL A 1 1191 ? 182.947 144.867 194.343 1.00 105.86 ? 1209 VAL A CG1 1 
ATOM   8829 C CG2 . VAL A 1 1191 ? 183.697 147.169 193.665 1.00 96.21  ? 1209 VAL A CG2 1 
ATOM   8830 N N   . THR A 1 1192 ? 185.410 143.874 196.630 1.00 113.19 ? 1210 THR A N   1 
ATOM   8831 C CA  . THR A 1 1192 ? 185.810 142.544 197.071 1.00 116.94 ? 1210 THR A CA  1 
ATOM   8832 C C   . THR A 1 1192 ? 184.594 141.821 197.638 1.00 119.24 ? 1210 THR A C   1 
ATOM   8833 O O   . THR A 1 1192 ? 183.509 142.392 197.758 1.00 117.25 ? 1210 THR A O   1 
ATOM   8834 C CB  . THR A 1 1192 ? 186.924 142.616 198.120 1.00 115.90 ? 1210 THR A CB  1 
ATOM   8835 O OG1 . THR A 1 1192 ? 186.347 142.818 199.416 1.00 114.61 ? 1210 THR A OG1 1 
ATOM   8836 C CG2 . THR A 1 1192 ? 187.894 143.751 197.818 1.00 113.74 ? 1210 THR A CG2 1 
ATOM   8837 N N   . GLY A 1 1193 ? 184.793 140.553 197.997 1.00 124.68 ? 1211 GLY A N   1 
ATOM   8838 C CA  . GLY A 1 1193 ? 183.760 139.743 198.604 1.00 128.59 ? 1211 GLY A CA  1 
ATOM   8839 C C   . GLY A 1 1193 ? 183.600 138.409 197.906 1.00 137.68 ? 1211 GLY A C   1 
ATOM   8840 O O   . GLY A 1 1193 ? 184.350 138.077 196.983 1.00 142.22 ? 1211 GLY A O   1 
ATOM   8841 N N   . PRO A 1 1194 ? 182.625 137.606 198.346 1.00 135.08 ? 1212 PRO A N   1 
ATOM   8842 C CA  . PRO A 1 1194 ? 182.413 136.301 197.698 1.00 136.54 ? 1212 PRO A CA  1 
ATOM   8843 C C   . PRO A 1 1194 ? 182.056 136.403 196.226 1.00 139.92 ? 1212 PRO A C   1 
ATOM   8844 O O   . PRO A 1 1194 ? 182.453 135.532 195.441 1.00 144.49 ? 1212 PRO A O   1 
ATOM   8845 C CB  . PRO A 1 1194 ? 181.268 135.683 198.515 1.00 131.01 ? 1212 PRO A CB  1 
ATOM   8846 C CG  . PRO A 1 1194 ? 180.619 136.824 199.209 1.00 127.72 ? 1212 PRO A CG  1 
ATOM   8847 C CD  . PRO A 1 1194 ? 181.700 137.814 199.474 1.00 126.16 ? 1212 PRO A CD  1 
ATOM   8848 N N   . SER A 1 1195 ? 181.323 137.441 195.824 1.00 136.64 ? 1213 SER A N   1 
ATOM   8849 C CA  . SER A 1 1195 ? 180.973 137.615 194.420 1.00 134.50 ? 1213 SER A CA  1 
ATOM   8850 C C   . SER A 1 1195 ? 182.139 138.107 193.574 1.00 137.40 ? 1213 SER A C   1 
ATOM   8851 O O   . SER A 1 1195 ? 182.078 137.999 192.345 1.00 139.50 ? 1213 SER A O   1 
ATOM   8852 C CB  . SER A 1 1195 ? 179.811 138.597 194.285 1.00 134.74 ? 1213 SER A CB  1 
ATOM   8853 O OG  . SER A 1 1195 ? 178.605 138.022 194.746 1.00 139.09 ? 1213 SER A OG  1 
ATOM   8854 N N   . SER A 1 1196 ? 183.193 138.642 194.199 1.00 137.77 ? 1214 SER A N   1 
ATOM   8855 C CA  . SER A 1 1196 ? 184.363 139.184 193.510 1.00 141.95 ? 1214 SER A CA  1 
ATOM   8856 C C   . SER A 1 1196 ? 185.605 138.521 194.097 1.00 145.12 ? 1214 SER A C   1 
ATOM   8857 O O   . SER A 1 1196 ? 186.272 139.104 194.965 1.00 146.77 ? 1214 SER A O   1 
ATOM   8858 C CB  . SER A 1 1196 ? 184.431 140.703 193.653 1.00 135.16 ? 1214 SER A CB  1 
ATOM   8859 O OG  . SER A 1 1196 ? 183.219 141.302 193.232 1.00 135.15 ? 1214 SER A OG  1 
ATOM   8860 N N   . PRO A 1 1197 ? 185.933 137.294 193.673 1.00 147.62 ? 1215 PRO A N   1 
ATOM   8861 C CA  . PRO A 1 1197 ? 187.187 136.683 194.147 1.00 151.88 ? 1215 PRO A CA  1 
ATOM   8862 C C   . PRO A 1 1197 ? 188.413 137.499 193.791 1.00 152.48 ? 1215 PRO A C   1 
ATOM   8863 O O   . PRO A 1 1197 ? 189.365 137.548 194.581 1.00 150.67 ? 1215 PRO A O   1 
ATOM   8864 C CB  . PRO A 1 1197 ? 187.203 135.306 193.466 1.00 151.68 ? 1215 PRO A CB  1 
ATOM   8865 C CG  . PRO A 1 1197 ? 185.845 135.098 192.906 1.00 146.36 ? 1215 PRO A CG  1 
ATOM   8866 C CD  . PRO A 1 1197 ? 185.218 136.430 192.717 1.00 144.32 ? 1215 PRO A CD  1 
ATOM   8867 N N   . SER A 1 1198 ? 188.415 138.146 192.627 1.00 151.43 ? 1216 SER A N   1 
ATOM   8868 C CA  . SER A 1 1198 ? 189.445 139.108 192.259 1.00 145.90 ? 1216 SER A CA  1 
ATOM   8869 C C   . SER A 1 1198 ? 189.007 140.513 192.677 1.00 141.06 ? 1216 SER A C   1 
ATOM   8870 O O   . SER A 1 1198 ? 187.843 140.875 192.481 1.00 137.10 ? 1216 SER A O   1 
ATOM   8871 C CB  . SER A 1 1198 ? 189.696 139.082 190.756 1.00 138.40 ? 1216 SER A CB  1 
ATOM   8872 O OG  . SER A 1 1198 ? 188.561 139.541 190.042 1.00 139.62 ? 1216 SER A OG  1 
ATOM   8873 N N   . PRO A 1 1199 ? 189.855 141.365 193.261 1.00 139.84 ? 1217 PRO A N   1 
ATOM   8874 C CA  . PRO A 1 1199 ? 189.392 142.725 193.585 1.00 133.88 ? 1217 PRO A CA  1 
ATOM   8875 C C   . PRO A 1 1199 ? 189.193 143.538 192.315 1.00 124.82 ? 1217 PRO A C   1 
ATOM   8876 O O   . PRO A 1 1199 ? 190.138 143.758 191.553 1.00 119.23 ? 1217 PRO A O   1 
ATOM   8877 C CB  . PRO A 1 1199 ? 190.521 143.297 194.454 1.00 133.04 ? 1217 PRO A CB  1 
ATOM   8878 C CG  . PRO A 1 1199 ? 191.399 142.154 194.795 1.00 130.65 ? 1217 PRO A CG  1 
ATOM   8879 C CD  . PRO A 1 1199 ? 191.248 141.166 193.698 1.00 137.13 ? 1217 PRO A CD  1 
ATOM   8880 N N   . VAL A 1 1200 ? 187.961 143.984 192.088 1.00 121.76 ? 1218 VAL A N   1 
ATOM   8881 C CA  . VAL A 1 1200 ? 187.636 144.787 190.913 1.00 112.26 ? 1218 VAL A CA  1 
ATOM   8882 C C   . VAL A 1 1200 ? 187.917 146.244 191.250 1.00 106.77 ? 1218 VAL A C   1 
ATOM   8883 O O   . VAL A 1 1200 ? 187.347 146.786 192.201 1.00 112.05 ? 1218 VAL A O   1 
ATOM   8884 C CB  . VAL A 1 1200 ? 186.175 144.588 190.482 1.00 105.26 ? 1218 VAL A CB  1 
ATOM   8885 C CG1 . VAL A 1 1200 ? 185.871 145.410 189.233 1.00 98.24  ? 1218 VAL A CG1 1 
ATOM   8886 C CG2 . VAL A 1 1200 ? 185.884 143.107 190.247 1.00 111.94 ? 1218 VAL A CG2 1 
ATOM   8887 N N   . LYS A 1 1201 ? 188.786 146.879 190.469 1.00 101.02 ? 1219 LYS A N   1 
ATOM   8888 C CA  . LYS A 1 1201 ? 189.287 148.216 190.760 1.00 95.78  ? 1219 LYS A CA  1 
ATOM   8889 C C   . LYS A 1 1201 ? 188.767 149.209 189.731 1.00 94.29  ? 1219 LYS A C   1 
ATOM   8890 O O   . LYS A 1 1201 ? 188.924 148.997 188.524 1.00 102.50 ? 1219 LYS A O   1 
ATOM   8891 C CB  . LYS A 1 1201 ? 190.815 148.228 190.778 1.00 99.65  ? 1219 LYS A CB  1 
ATOM   8892 C CG  . LYS A 1 1201 ? 191.405 147.777 192.102 1.00 107.91 ? 1219 LYS A CG  1 
ATOM   8893 C CD  . LYS A 1 1201 ? 192.917 147.660 192.036 1.00 123.37 ? 1219 LYS A CD  1 
ATOM   8894 C CE  . LYS A 1 1201 ? 193.523 147.550 193.426 1.00 135.49 ? 1219 LYS A CE  1 
ATOM   8895 N NZ  . LYS A 1 1201 ? 195.011 147.526 193.392 1.00 146.59 ? 1219 LYS A NZ  1 
ATOM   8896 N N   . PHE A 1 1202 ? 188.149 150.283 190.217 1.00 90.97  ? 1220 PHE A N   1 
ATOM   8897 C CA  . PHE A 1 1202 ? 187.757 151.429 189.408 1.00 88.33  ? 1220 PHE A CA  1 
ATOM   8898 C C   . PHE A 1 1202 ? 188.550 152.645 189.861 1.00 92.63  ? 1220 PHE A C   1 
ATOM   8899 O O   . PHE A 1 1202 ? 188.811 152.810 191.055 1.00 102.30 ? 1220 PHE A O   1 
ATOM   8900 C CB  . PHE A 1 1202 ? 186.261 151.726 189.536 1.00 85.45  ? 1220 PHE A CB  1 
ATOM   8901 C CG  . PHE A 1 1202 ? 185.379 150.539 189.294 1.00 88.55  ? 1220 PHE A CG  1 
ATOM   8902 C CD1 . PHE A 1 1202 ? 185.384 149.891 188.074 1.00 91.74  ? 1220 PHE A CD1 1 
ATOM   8903 C CD2 . PHE A 1 1202 ? 184.534 150.079 190.285 1.00 91.86  ? 1220 PHE A CD2 1 
ATOM   8904 C CE1 . PHE A 1 1202 ? 184.569 148.803 187.852 1.00 94.22  ? 1220 PHE A CE1 1 
ATOM   8905 C CE2 . PHE A 1 1202 ? 183.719 148.993 190.068 1.00 94.45  ? 1220 PHE A CE2 1 
ATOM   8906 C CZ  . PHE A 1 1202 ? 183.736 148.354 188.851 1.00 98.84  ? 1220 PHE A CZ  1 
ATOM   8907 N N   . LEU A 1 1203 ? 188.937 153.486 188.905 1.00 88.50  ? 1221 LEU A N   1 
ATOM   8908 C CA  . LEU A 1 1203 ? 189.627 154.741 189.174 1.00 89.59  ? 1221 LEU A CA  1 
ATOM   8909 C C   . LEU A 1 1203 ? 188.774 155.886 188.657 1.00 93.90  ? 1221 LEU A C   1 
ATOM   8910 O O   . LEU A 1 1203 ? 188.386 155.891 187.484 1.00 108.94 ? 1221 LEU A O   1 
ATOM   8911 C CB  . LEU A 1 1203 ? 191.007 154.767 188.514 1.00 99.94  ? 1221 LEU A CB  1 
ATOM   8912 C CG  . LEU A 1 1203 ? 192.036 153.799 189.101 1.00 107.96 ? 1221 LEU A CG  1 
ATOM   8913 C CD1 . LEU A 1 1203 ? 193.123 153.485 188.085 1.00 109.64 ? 1221 LEU A CD1 1 
ATOM   8914 C CD2 . LEU A 1 1203 ? 192.642 154.368 190.373 1.00 105.06 ? 1221 LEU A CD2 1 
ATOM   8915 N N   . ILE A 1 1204 ? 188.488 156.850 189.529 1.00 92.40  ? 1222 ILE A N   1 
ATOM   8916 C CA  . ILE A 1 1204 ? 187.648 157.999 189.210 1.00 92.03  ? 1222 ILE A CA  1 
ATOM   8917 C C   . ILE A 1 1204 ? 188.464 159.253 189.475 1.00 105.58 ? 1222 ILE A C   1 
ATOM   8918 O O   . ILE A 1 1204 ? 189.004 159.427 190.575 1.00 115.38 ? 1222 ILE A O   1 
ATOM   8919 C CB  . ILE A 1 1204 ? 186.348 158.000 190.031 1.00 90.60  ? 1222 ILE A CB  1 
ATOM   8920 C CG1 . ILE A 1 1204 ? 185.429 156.865 189.579 1.00 89.03  ? 1222 ILE A CG1 1 
ATOM   8921 C CG2 . ILE A 1 1204 ? 185.623 159.333 189.899 1.00 95.33  ? 1222 ILE A CG2 1 
ATOM   8922 C CD1 . ILE A 1 1204 ? 184.498 156.375 190.659 1.00 91.93  ? 1222 ILE A CD1 1 
ATOM   8923 N N   . ASP A 1 1205 ? 188.555 160.118 188.469 1.00 104.22 ? 1223 ASP A N   1 
ATOM   8924 C CA  . ASP A 1 1205 ? 189.250 161.393 188.584 1.00 111.21 ? 1223 ASP A CA  1 
ATOM   8925 C C   . ASP A 1 1205 ? 188.437 162.439 187.831 1.00 110.50 ? 1223 ASP A C   1 
ATOM   8926 O O   . ASP A 1 1205 ? 187.306 162.187 187.405 1.00 111.07 ? 1223 ASP A O   1 
ATOM   8927 C CB  . ASP A 1 1205 ? 190.686 161.279 188.058 1.00 115.79 ? 1223 ASP A CB  1 
ATOM   8928 C CG  . ASP A 1 1205 ? 190.741 161.068 186.563 1.00 126.03 ? 1223 ASP A CG  1 
ATOM   8929 O OD1 . ASP A 1 1205 ? 190.715 162.071 185.820 1.00 130.69 ? 1223 ASP A OD1 1 
ATOM   8930 O OD2 . ASP A 1 1205 ? 190.810 159.899 186.128 1.00 126.79 ? 1223 ASP A OD2 1 
ATOM   8931 N N   . THR A 1 1206 ? 189.021 163.626 187.661 1.00 110.66 ? 1224 THR A N   1 
ATOM   8932 C CA  . THR A 1 1206 ? 188.298 164.727 187.037 1.00 114.63 ? 1224 THR A CA  1 
ATOM   8933 C C   . THR A 1 1206 ? 187.985 164.467 185.569 1.00 120.41 ? 1224 THR A C   1 
ATOM   8934 O O   . THR A 1 1206 ? 187.060 165.086 185.031 1.00 125.25 ? 1224 THR A O   1 
ATOM   8935 C CB  . THR A 1 1206 ? 189.098 166.023 187.161 1.00 118.99 ? 1224 THR A CB  1 
ATOM   8936 O OG1 . THR A 1 1206 ? 190.341 165.888 186.461 1.00 124.00 ? 1224 THR A OG1 1 
ATOM   8937 C CG2 . THR A 1 1206 ? 189.375 166.347 188.621 1.00 123.09 ? 1224 THR A CG2 1 
ATOM   8938 N N   . HIS A 1 1207 ? 188.725 163.576 184.909 1.00 117.57 ? 1225 HIS A N   1 
ATOM   8939 C CA  . HIS A 1 1207 ? 188.476 163.304 183.498 1.00 113.31 ? 1225 HIS A CA  1 
ATOM   8940 C C   . HIS A 1 1207 ? 187.266 162.398 183.309 1.00 112.01 ? 1225 HIS A C   1 
ATOM   8941 O O   . HIS A 1 1207 ? 186.355 162.722 182.539 1.00 109.34 ? 1225 HIS A O   1 
ATOM   8942 C CB  . HIS A 1 1207 ? 189.713 162.675 182.859 1.00 111.11 ? 1225 HIS A CB  1 
ATOM   8943 C CG  . HIS A 1 1207 ? 190.949 163.506 182.992 1.00 118.77 ? 1225 HIS A CG  1 
ATOM   8944 N ND1 . HIS A 1 1207 ? 191.905 163.271 183.957 1.00 128.75 ? 1225 HIS A ND1 1 
ATOM   8945 C CD2 . HIS A 1 1207 ? 191.386 164.572 182.281 1.00 121.48 ? 1225 HIS A CD2 1 
ATOM   8946 C CE1 . HIS A 1 1207 ? 192.878 164.156 183.834 1.00 130.12 ? 1225 HIS A CE1 1 
ATOM   8947 N NE2 . HIS A 1 1207 ? 192.587 164.957 182.825 1.00 131.43 ? 1225 HIS A NE2 1 
ATOM   8948 N N   . ASN A 1 1208 ? 187.238 161.266 184.009 1.00 108.58 ? 1226 ASN A N   1 
ATOM   8949 C CA  . ASN A 1 1208 ? 186.205 160.246 183.852 1.00 97.38  ? 1226 ASN A CA  1 
ATOM   8950 C C   . ASN A 1 1208 ? 185.216 160.272 185.012 1.00 93.95  ? 1226 ASN A C   1 
ATOM   8951 O O   . ASN A 1 1208 ? 184.728 159.231 185.455 1.00 95.28  ? 1226 ASN A O   1 
ATOM   8952 C CB  . ASN A 1 1208 ? 186.830 158.859 183.724 1.00 101.94 ? 1226 ASN A CB  1 
ATOM   8953 C CG  . ASN A 1 1208 ? 187.679 158.487 184.921 1.00 111.34 ? 1226 ASN A CG  1 
ATOM   8954 O OD1 . ASN A 1 1208 ? 187.932 159.312 185.798 1.00 110.22 ? 1226 ASN A OD1 1 
ATOM   8955 N ND2 . ASN A 1 1208 ? 188.126 157.238 184.963 1.00 115.90 ? 1226 ASN A ND2 1 
ATOM   8956 N N   . ARG A 1 1209 ? 184.914 161.466 185.523 1.00 97.96  ? 1227 ARG A N   1 
ATOM   8957 C CA  . ARG A 1 1209 ? 183.964 161.570 186.625 1.00 97.34  ? 1227 ARG A CA  1 
ATOM   8958 C C   . ARG A 1 1209 ? 182.570 161.138 186.191 1.00 94.21  ? 1227 ARG A C   1 
ATOM   8959 O O   . ARG A 1 1209 ? 181.864 160.457 186.943 1.00 95.34  ? 1227 ARG A O   1 
ATOM   8960 C CB  . ARG A 1 1209 ? 183.936 163.001 187.169 1.00 102.03 ? 1227 ARG A CB  1 
ATOM   8961 C CG  . ARG A 1 1209 ? 183.775 163.116 188.685 1.00 107.33 ? 1227 ARG A CG  1 
ATOM   8962 C CD  . ARG A 1 1209 ? 184.507 164.331 189.227 1.00 115.84 ? 1227 ARG A CD  1 
ATOM   8963 N NE  . ARG A 1 1209 ? 184.048 165.567 188.603 1.00 122.46 ? 1227 ARG A NE  1 
ATOM   8964 C CZ  . ARG A 1 1209 ? 182.956 166.239 188.948 1.00 130.68 ? 1227 ARG A CZ  1 
ATOM   8965 N NH1 . ARG A 1 1209 ? 182.153 165.821 189.916 1.00 130.58 ? 1227 ARG A NH1 1 
ATOM   8966 N NH2 . ARG A 1 1209 ? 182.658 167.362 188.301 1.00 133.75 ? 1227 ARG A NH2 1 
ATOM   8967 N N   . LEU A 1 1210 ? 182.161 161.515 184.981 1.00 91.66  ? 1228 LEU A N   1 
ATOM   8968 C CA  . LEU A 1 1210 ? 180.851 161.135 184.467 1.00 88.63  ? 1228 LEU A CA  1 
ATOM   8969 C C   . LEU A 1 1210 ? 180.812 159.721 183.904 1.00 86.35  ? 1228 LEU A C   1 
ATOM   8970 O O   . LEU A 1 1210 ? 179.717 159.203 183.667 1.00 86.31  ? 1228 LEU A O   1 
ATOM   8971 C CB  . LEU A 1 1210 ? 180.400 162.110 183.373 1.00 85.76  ? 1228 LEU A CB  1 
ATOM   8972 C CG  . LEU A 1 1210 ? 179.383 163.189 183.755 1.00 87.18  ? 1228 LEU A CG  1 
ATOM   8973 C CD1 . LEU A 1 1210 ? 178.019 162.581 184.060 1.00 101.23 ? 1228 LEU A CD1 1 
ATOM   8974 C CD2 . LEU A 1 1210 ? 179.878 164.025 184.924 1.00 93.85  ? 1228 LEU A CD2 1 
ATOM   8975 N N   . LEU A 1 1211 ? 181.962 159.085 183.690 1.00 82.86  ? 1229 LEU A N   1 
ATOM   8976 C CA  . LEU A 1 1211 ? 181.993 157.779 183.044 1.00 80.17  ? 1229 LEU A CA  1 
ATOM   8977 C C   . LEU A 1 1211 ? 181.356 156.738 183.952 1.00 82.89  ? 1229 LEU A C   1 
ATOM   8978 O O   . LEU A 1 1211 ? 181.856 156.469 185.049 1.00 92.85  ? 1229 LEU A O   1 
ATOM   8979 C CB  . LEU A 1 1211 ? 183.430 157.385 182.710 1.00 83.67  ? 1229 LEU A CB  1 
ATOM   8980 C CG  . LEU A 1 1211 ? 183.642 156.575 181.431 1.00 89.26  ? 1229 LEU A CG  1 
ATOM   8981 C CD1 . LEU A 1 1211 ? 185.125 156.473 181.120 1.00 95.32  ? 1229 LEU A CD1 1 
ATOM   8982 C CD2 . LEU A 1 1211 ? 183.023 155.194 181.541 1.00 85.47  ? 1229 LEU A CD2 1 
ATOM   8983 N N   . LEU A 1 1212 ? 180.254 156.149 183.497 1.00 77.54  ? 1230 LEU A N   1 
ATOM   8984 C CA  . LEU A 1 1212 ? 179.578 155.094 184.248 1.00 76.74  ? 1230 LEU A CA  1 
ATOM   8985 C C   . LEU A 1 1212 ? 180.399 153.823 184.098 1.00 82.08  ? 1230 LEU A C   1 
ATOM   8986 O O   . LEU A 1 1212 ? 180.111 152.964 183.265 1.00 78.60  ? 1230 LEU A O   1 
ATOM   8987 C CB  . LEU A 1 1212 ? 178.152 154.902 183.750 1.00 77.07  ? 1230 LEU A CB  1 
ATOM   8988 C CG  . LEU A 1 1212 ? 177.304 153.918 184.559 1.00 81.51  ? 1230 LEU A CG  1 
ATOM   8989 C CD1 . LEU A 1 1212 ? 176.065 154.601 185.103 1.00 91.55  ? 1230 LEU A CD1 1 
ATOM   8990 C CD2 . LEU A 1 1212 ? 176.911 152.711 183.723 1.00 84.14  ? 1230 LEU A CD2 1 
ATOM   8991 N N   . GLN A 1 1213 ? 181.441 153.701 184.915 1.00 89.31  ? 1231 GLN A N   1 
ATOM   8992 C CA  . GLN A 1 1213 ? 182.266 152.501 184.872 1.00 84.91  ? 1231 GLN A CA  1 
ATOM   8993 C C   . GLN A 1 1213 ? 181.450 151.328 185.387 1.00 87.73  ? 1231 GLN A C   1 
ATOM   8994 O O   . GLN A 1 1213 ? 180.620 151.492 186.279 1.00 92.54  ? 1231 GLN A O   1 
ATOM   8995 C CB  . GLN A 1 1213 ? 183.536 152.680 185.703 1.00 77.39  ? 1231 GLN A CB  1 
ATOM   8996 C CG  . GLN A 1 1213 ? 184.227 154.026 185.504 1.00 74.21  ? 1231 GLN A CG  1 
ATOM   8997 C CD  . GLN A 1 1213 ? 185.691 154.016 185.893 1.00 89.11  ? 1231 GLN A CD  1 
ATOM   8998 O OE1 . GLN A 1 1213 ? 186.389 153.017 185.725 1.00 91.58  ? 1231 GLN A OE1 1 
ATOM   8999 N NE2 . GLN A 1 1213 ? 186.166 155.140 186.410 1.00 99.40  ? 1231 GLN A NE2 1 
ATOM   9000 N N   . THR A 1 1214 ? 181.672 150.147 184.813 1.00 88.73  ? 1232 THR A N   1 
ATOM   9001 C CA  . THR A 1 1214 ? 180.837 148.987 185.092 1.00 92.51  ? 1232 THR A CA  1 
ATOM   9002 C C   . THR A 1 1214 ? 181.687 147.730 185.184 1.00 94.40  ? 1232 THR A C   1 
ATOM   9003 O O   . THR A 1 1214 ? 182.806 147.666 184.672 1.00 100.37 ? 1232 THR A O   1 
ATOM   9004 C CB  . THR A 1 1214 ? 179.756 148.799 184.018 1.00 100.72 ? 1232 THR A CB  1 
ATOM   9005 O OG1 . THR A 1 1214 ? 179.163 147.502 184.157 1.00 103.72 ? 1232 THR A OG1 1 
ATOM   9006 C CG2 . THR A 1 1214 ? 180.339 148.947 182.616 1.00 106.01 ? 1232 THR A CG2 1 
ATOM   9007 N N   . ALA A 1 1215 ? 181.131 146.725 185.858 1.00 95.48  ? 1233 ALA A N   1 
ATOM   9008 C CA  . ALA A 1 1215 ? 181.751 145.414 185.945 1.00 95.21  ? 1233 ALA A CA  1 
ATOM   9009 C C   . ALA A 1 1215 ? 180.673 144.386 186.252 1.00 99.76  ? 1233 ALA A C   1 
ATOM   9010 O O   . ALA A 1 1215 ? 179.609 144.715 186.782 1.00 106.20 ? 1233 ALA A O   1 
ATOM   9011 C CB  . ALA A 1 1215 ? 182.849 145.378 187.013 1.00 91.06  ? 1233 ALA A CB  1 
ATOM   9012 N N   . GLU A 1 1216 ? 180.965 143.134 185.908 1.00 103.09 ? 1234 GLU A N   1 
ATOM   9013 C CA  . GLU A 1 1216 ? 180.069 142.008 186.128 1.00 108.48 ? 1234 GLU A CA  1 
ATOM   9014 C C   . GLU A 1 1216 ? 180.677 141.072 187.161 1.00 111.78 ? 1234 GLU A C   1 
ATOM   9015 O O   . GLU A 1 1216 ? 181.890 140.838 187.156 1.00 116.49 ? 1234 GLU A O   1 
ATOM   9016 C CB  . GLU A 1 1216 ? 179.816 141.246 184.825 1.00 117.58 ? 1234 GLU A CB  1 
ATOM   9017 C CG  . GLU A 1 1216 ? 178.906 141.977 183.839 1.00 131.88 ? 1234 GLU A CG  1 
ATOM   9018 C CD  . GLU A 1 1216 ? 177.960 141.054 183.086 1.00 151.64 ? 1234 GLU A CD  1 
ATOM   9019 O OE1 . GLU A 1 1216 ? 178.259 139.848 182.953 1.00 158.39 ? 1234 GLU A OE1 1 
ATOM   9020 O OE2 . GLU A 1 1216 ? 176.907 141.540 182.624 1.00 153.93 ? 1234 GLU A OE2 1 
ATOM   9021 N N   . LEU A 1 1217 ? 179.832 140.541 188.042 1.00 112.87 ? 1235 LEU A N   1 
ATOM   9022 C CA  . LEU A 1 1217 ? 180.249 139.665 189.126 1.00 110.30 ? 1235 LEU A CA  1 
ATOM   9023 C C   . LEU A 1 1217 ? 179.596 138.300 188.966 1.00 118.26 ? 1235 LEU A C   1 
ATOM   9024 O O   . LEU A 1 1217 ? 178.612 138.132 188.241 1.00 125.52 ? 1235 LEU A O   1 
ATOM   9025 C CB  . LEU A 1 1217 ? 179.886 140.266 190.489 1.00 111.86 ? 1235 LEU A CB  1 
ATOM   9026 C CG  . LEU A 1 1217 ? 180.239 141.741 190.692 1.00 109.17 ? 1235 LEU A CG  1 
ATOM   9027 C CD1 . LEU A 1 1217 ? 179.826 142.194 192.080 1.00 114.17 ? 1235 LEU A CD1 1 
ATOM   9028 C CD2 . LEU A 1 1217 ? 181.723 141.981 190.469 1.00 109.19 ? 1235 LEU A CD2 1 
ATOM   9029 N N   . ALA A 1 1218 ? 180.160 137.316 189.658 1.00 117.60 ? 1236 ALA A N   1 
ATOM   9030 C CA  . ALA A 1 1218 ? 179.645 135.960 189.603 1.00 125.79 ? 1236 ALA A CA  1 
ATOM   9031 C C   . ALA A 1 1218 ? 178.351 135.847 190.406 1.00 129.75 ? 1236 ALA A C   1 
ATOM   9032 O O   . ALA A 1 1218 ? 177.988 136.730 191.187 1.00 128.74 ? 1236 ALA A O   1 
ATOM   9033 C CB  . ALA A 1 1218 ? 180.684 134.972 190.129 1.00 130.05 ? 1236 ALA A CB  1 
ATOM   9034 N N   . VAL A 1 1219 ? 177.653 134.734 190.202 1.00 129.73 ? 1237 VAL A N   1 
ATOM   9035 C CA  . VAL A 1 1219 ? 176.391 134.448 190.874 1.00 130.01 ? 1237 VAL A CA  1 
ATOM   9036 C C   . VAL A 1 1219 ? 176.694 133.632 192.122 1.00 136.85 ? 1237 VAL A C   1 
ATOM   9037 O O   . VAL A 1 1219 ? 177.316 132.567 192.042 1.00 141.82 ? 1237 VAL A O   1 
ATOM   9038 C CB  . VAL A 1 1219 ? 175.420 133.699 189.948 1.00 128.78 ? 1237 VAL A CB  1 
ATOM   9039 C CG1 . VAL A 1 1219 ? 174.151 133.310 190.703 1.00 133.03 ? 1237 VAL A CG1 1 
ATOM   9040 C CG2 . VAL A 1 1219 ? 175.084 134.549 188.727 1.00 127.15 ? 1237 VAL A CG2 1 
ATOM   9041 N N   . VAL A 1 1220 ? 176.256 134.130 193.274 1.00 136.13 ? 1238 VAL A N   1 
ATOM   9042 C CA  . VAL A 1 1220 ? 176.405 133.417 194.538 1.00 142.44 ? 1238 VAL A CA  1 
ATOM   9043 C C   . VAL A 1 1220 ? 175.290 133.867 195.469 1.00 144.00 ? 1238 VAL A C   1 
ATOM   9044 O O   . VAL A 1 1220 ? 174.992 135.060 195.569 1.00 141.43 ? 1238 VAL A O   1 
ATOM   9045 C CB  . VAL A 1 1220 ? 177.800 133.644 195.166 1.00 140.74 ? 1238 VAL A CB  1 
ATOM   9046 C CG1 . VAL A 1 1220 ? 178.084 135.130 195.387 1.00 138.19 ? 1238 VAL A CG1 1 
ATOM   9047 C CG2 . VAL A 1 1220 ? 177.928 132.874 196.472 1.00 142.01 ? 1238 VAL A CG2 1 
ATOM   9048 N N   . GLN A 1 1221 ? 174.679 132.897 196.152 1.00 143.59 ? 1239 GLN A N   1 
ATOM   9049 C CA  . GLN A 1 1221 ? 173.549 133.133 197.041 1.00 141.18 ? 1239 GLN A CA  1 
ATOM   9050 C C   . GLN A 1 1221 ? 174.024 133.041 198.486 1.00 147.75 ? 1239 GLN A C   1 
ATOM   9051 O O   . GLN A 1 1221 ? 174.426 131.946 198.905 1.00 151.67 ? 1239 GLN A O   1 
ATOM   9052 C CB  . GLN A 1 1221 ? 172.446 132.107 196.772 1.00 136.57 ? 1239 GLN A CB  1 
ATOM   9053 C CG  . GLN A 1 1221 ? 171.294 132.096 197.778 1.00 142.89 ? 1239 GLN A CG  1 
ATOM   9054 C CD  . GLN A 1 1221 ? 170.713 133.475 198.026 1.00 148.04 ? 1239 GLN A CD  1 
ATOM   9055 O OE1 . GLN A 1 1221 ? 170.297 134.162 197.093 1.00 147.49 ? 1239 GLN A OE1 1 
ATOM   9056 N NE2 . GLN A 1 1221 ? 170.687 133.889 199.287 1.00 150.05 ? 1239 GLN A NE2 1 
ATOM   9057 N N   . PRO A 1 1222 ? 174.012 134.116 199.301 1.00 149.11 ? 1240 PRO A N   1 
ATOM   9058 C CA  . PRO A 1 1222 ? 173.600 135.503 199.036 1.00 142.42 ? 1240 PRO A CA  1 
ATOM   9059 C C   . PRO A 1 1222 ? 174.666 136.287 198.283 1.00 138.27 ? 1240 PRO A C   1 
ATOM   9060 O O   . PRO A 1 1222 ? 175.857 136.025 198.422 1.00 138.82 ? 1240 PRO A O   1 
ATOM   9061 C CB  . PRO A 1 1222 ? 173.362 136.057 200.443 1.00 141.00 ? 1240 PRO A CB  1 
ATOM   9062 C CG  . PRO A 1 1222 ? 174.379 135.352 201.279 1.00 139.69 ? 1240 PRO A CG  1 
ATOM   9063 C CD  . PRO A 1 1222 ? 174.511 133.967 200.682 1.00 147.02 ? 1240 PRO A CD  1 
ATOM   9064 N N   . THR A 1 1223 ? 174.247 137.261 197.481 1.00 135.74 ? 1241 THR A N   1 
ATOM   9065 C CA  . THR A 1 1223 ? 175.157 138.103 196.709 1.00 137.02 ? 1241 THR A CA  1 
ATOM   9066 C C   . THR A 1 1223 ? 175.507 139.314 197.563 1.00 134.01 ? 1241 THR A C   1 
ATOM   9067 O O   . THR A 1 1223 ? 174.695 140.226 197.716 1.00 133.55 ? 1241 THR A O   1 
ATOM   9068 C CB  . THR A 1 1223 ? 174.508 138.514 195.392 1.00 138.46 ? 1241 THR A CB  1 
ATOM   9069 O OG1 . THR A 1 1223 ? 174.171 137.342 194.640 1.00 141.79 ? 1241 THR A OG1 1 
ATOM   9070 C CG2 . THR A 1 1223 ? 175.435 139.397 194.570 1.00 130.88 ? 1241 THR A CG2 1 
ATOM   9071 N N   . ALA A 1 1224 ? 176.721 139.328 198.113 1.00 129.58 ? 1242 ALA A N   1 
ATOM   9072 C CA  . ALA A 1 1224 ? 177.173 140.391 199.005 1.00 128.38 ? 1242 ALA A CA  1 
ATOM   9073 C C   . ALA A 1 1224 ? 178.583 140.806 198.622 1.00 121.77 ? 1242 ALA A C   1 
ATOM   9074 O O   . ALA A 1 1224 ? 179.414 139.952 198.301 1.00 123.94 ? 1242 ALA A O   1 
ATOM   9075 C CB  . ALA A 1 1224 ? 177.139 139.937 200.468 1.00 133.92 ? 1242 ALA A CB  1 
ATOM   9076 N N   . VAL A 1 1225 ? 178.845 142.115 198.648 1.00 118.91 ? 1243 VAL A N   1 
ATOM   9077 C CA  . VAL A 1 1225 ? 180.146 142.667 198.289 1.00 113.71 ? 1243 VAL A CA  1 
ATOM   9078 C C   . VAL A 1 1225 ? 180.522 143.790 199.245 1.00 112.96 ? 1243 VAL A C   1 
ATOM   9079 O O   . VAL A 1 1225 ? 179.675 144.579 199.683 1.00 119.69 ? 1243 VAL A O   1 
ATOM   9080 C CB  . VAL A 1 1225 ? 180.179 143.184 196.830 1.00 111.59 ? 1243 VAL A CB  1 
ATOM   9081 C CG1 . VAL A 1 1225 ? 179.641 142.141 195.877 1.00 116.74 ? 1243 VAL A CG1 1 
ATOM   9082 C CG2 . VAL A 1 1225 ? 179.395 144.483 196.690 1.00 105.87 ? 1243 VAL A CG2 1 
ATOM   9083 N N   . ASN A 1 1226 ? 181.814 143.848 199.569 1.00 110.01 ? 1244 ASN A N   1 
ATOM   9084 C CA  . ASN A 1 1226 ? 182.425 145.024 200.167 1.00 107.42 ? 1244 ASN A CA  1 
ATOM   9085 C C   . ASN A 1 1226 ? 182.882 145.965 199.065 1.00 103.33 ? 1244 ASN A C   1 
ATOM   9086 O O   . ASN A 1 1226 ? 183.469 145.533 198.068 1.00 111.55 ? 1244 ASN A O   1 
ATOM   9087 C CB  . ASN A 1 1226 ? 183.637 144.660 201.026 1.00 116.14 ? 1244 ASN A CB  1 
ATOM   9088 C CG  . ASN A 1 1226 ? 183.265 144.116 202.387 1.00 127.77 ? 1244 ASN A CG  1 
ATOM   9089 O OD1 . ASN A 1 1226 ? 182.357 144.616 203.048 1.00 127.79 ? 1244 ASN A OD1 1 
ATOM   9090 N ND2 . ASN A 1 1226 ? 183.994 143.099 202.826 1.00 134.50 ? 1244 ASN A ND2 1 
ATOM   9091 N N   . ILE A 1 1227 ? 182.614 147.252 199.258 1.00 98.20  ? 1245 ILE A N   1 
ATOM   9092 C CA  . ILE A 1 1227 ? 183.083 148.319 198.382 1.00 96.92  ? 1245 ILE A CA  1 
ATOM   9093 C C   . ILE A 1 1227 ? 183.892 149.273 199.244 1.00 95.16  ? 1245 ILE A C   1 
ATOM   9094 O O   . ILE A 1 1227 ? 183.337 149.937 200.127 1.00 109.76 ? 1245 ILE A O   1 
ATOM   9095 C CB  . ILE A 1 1227 ? 181.914 149.042 197.692 1.00 102.99 ? 1245 ILE A CB  1 
ATOM   9096 C CG1 . ILE A 1 1227 ? 181.229 148.107 196.689 1.00 100.80 ? 1245 ILE A CG1 1 
ATOM   9097 C CG2 . ILE A 1 1227 ? 182.390 150.322 197.012 1.00 103.27 ? 1245 ILE A CG2 1 
ATOM   9098 C CD1 . ILE A 1 1227 ? 179.723 148.174 196.730 1.00 102.08 ? 1245 ILE A CD1 1 
ATOM   9099 N N   . SER A 1 1228 ? 185.198 149.336 198.994 1.00 89.16  ? 1246 SER A N   1 
ATOM   9100 C CA  . SER A 1 1228 ? 186.123 150.154 199.767 1.00 99.00  ? 1246 SER A CA  1 
ATOM   9101 C C   . SER A 1 1228 ? 186.679 151.241 198.863 1.00 102.58 ? 1246 SER A C   1 
ATOM   9102 O O   . SER A 1 1228 ? 187.377 150.943 197.889 1.00 110.35 ? 1246 SER A O   1 
ATOM   9103 C CB  . SER A 1 1228 ? 187.254 149.302 200.344 1.00 112.81 ? 1246 SER A CB  1 
ATOM   9104 O OG  . SER A 1 1228 ? 187.880 148.537 199.330 1.00 116.10 ? 1246 SER A OG  1 
ATOM   9105 N N   . ALA A 1 1229 ? 186.369 152.492 199.182 1.00 101.55 ? 1247 ALA A N   1 
ATOM   9106 C CA  . ALA A 1 1229 ? 186.854 153.646 198.437 1.00 103.03 ? 1247 ALA A CA  1 
ATOM   9107 C C   . ALA A 1 1229 ? 187.995 154.286 199.208 1.00 108.18 ? 1247 ALA A C   1 
ATOM   9108 O O   . ALA A 1 1229 ? 187.886 154.492 200.421 1.00 121.05 ? 1247 ALA A O   1 
ATOM   9109 C CB  . ALA A 1 1229 ? 185.736 154.664 198.205 1.00 100.99 ? 1247 ALA A CB  1 
ATOM   9110 N N   . ASN A 1 1230 ? 189.085 154.593 198.506 1.00 105.69 ? 1248 ASN A N   1 
ATOM   9111 C CA  . ASN A 1 1230 ? 190.237 155.273 199.085 1.00 109.71 ? 1248 ASN A CA  1 
ATOM   9112 C C   . ASN A 1 1230 ? 190.657 156.409 198.167 1.00 113.40 ? 1248 ASN A C   1 
ATOM   9113 O O   . ASN A 1 1230 ? 190.769 156.217 196.953 1.00 121.71 ? 1248 ASN A O   1 
ATOM   9114 C CB  . ASN A 1 1230 ? 191.407 154.306 199.295 1.00 114.78 ? 1248 ASN A CB  1 
ATOM   9115 C CG  . ASN A 1 1230 ? 190.968 152.969 199.861 1.00 114.80 ? 1248 ASN A CG  1 
ATOM   9116 O OD1 . ASN A 1 1230 ? 190.177 152.253 199.249 1.00 111.04 ? 1248 ASN A OD1 1 
ATOM   9117 N ND2 . ASN A 1 1230 ? 191.482 152.626 201.037 1.00 117.26 ? 1248 ASN A ND2 1 
ATOM   9118 N N   . GLY A 1 1231 ? 190.899 157.583 198.748 1.00 112.26 ? 1249 GLY A N   1 
ATOM   9119 C CA  . GLY A 1 1231 ? 191.322 158.737 197.978 1.00 118.06 ? 1249 GLY A CA  1 
ATOM   9120 C C   . GLY A 1 1231 ? 190.793 160.052 198.507 1.00 123.86 ? 1249 GLY A C   1 
ATOM   9121 O O   . GLY A 1 1231 ? 190.984 160.383 199.681 1.00 135.20 ? 1249 GLY A O   1 
ATOM   9122 N N   . PHE A 1 1232 ? 190.128 160.815 197.642 1.00 119.48 ? 1250 PHE A N   1 
ATOM   9123 C CA  . PHE A 1 1232 ? 189.640 162.140 198.000 1.00 126.65 ? 1250 PHE A CA  1 
ATOM   9124 C C   . PHE A 1 1232 ? 188.525 162.524 197.041 1.00 130.07 ? 1250 PHE A C   1 
ATOM   9125 O O   . PHE A 1 1232 ? 188.695 162.408 195.824 1.00 130.80 ? 1250 PHE A O   1 
ATOM   9126 C CB  . PHE A 1 1232 ? 190.773 163.167 197.942 1.00 130.20 ? 1250 PHE A CB  1 
ATOM   9127 C CG  . PHE A 1 1232 ? 190.331 164.571 198.221 1.00 140.99 ? 1250 PHE A CG  1 
ATOM   9128 C CD1 . PHE A 1 1232 ? 190.027 164.973 199.509 1.00 143.56 ? 1250 PHE A CD1 1 
ATOM   9129 C CD2 . PHE A 1 1232 ? 190.220 165.490 197.193 1.00 150.00 ? 1250 PHE A CD2 1 
ATOM   9130 C CE1 . PHE A 1 1232 ? 189.621 166.268 199.767 1.00 149.99 ? 1250 PHE A CE1 1 
ATOM   9131 C CE2 . PHE A 1 1232 ? 189.814 166.785 197.444 1.00 152.19 ? 1250 PHE A CE2 1 
ATOM   9132 C CZ  . PHE A 1 1232 ? 189.514 167.175 198.732 1.00 153.76 ? 1250 PHE A CZ  1 
ATOM   9133 N N   . GLY A 1 1233 ? 187.394 162.973 197.590 1.00 129.38 ? 1251 GLY A N   1 
ATOM   9134 C CA  . GLY A 1 1233 ? 186.256 163.407 196.794 1.00 122.83 ? 1251 GLY A CA  1 
ATOM   9135 C C   . GLY A 1 1233 ? 184.983 162.663 197.140 1.00 117.00 ? 1251 GLY A C   1 
ATOM   9136 O O   . GLY A 1 1233 ? 184.634 162.532 198.315 1.00 124.74 ? 1251 GLY A O   1 
ATOM   9137 N N   . PHE A 1 1234 ? 184.270 162.173 196.129 1.00 102.29 ? 1252 PHE A N   1 
ATOM   9138 C CA  . PHE A 1 1234 ? 183.094 161.354 196.374 1.00 99.08  ? 1252 PHE A CA  1 
ATOM   9139 C C   . PHE A 1 1234 ? 182.826 160.481 195.161 1.00 94.52  ? 1252 PHE A C   1 
ATOM   9140 O O   . PHE A 1 1234 ? 183.174 160.835 194.032 1.00 104.65 ? 1252 PHE A O   1 
ATOM   9141 C CB  . PHE A 1 1234 ? 181.864 162.211 196.689 1.00 110.37 ? 1252 PHE A CB  1 
ATOM   9142 C CG  . PHE A 1 1234 ? 181.113 162.667 195.473 1.00 102.32 ? 1252 PHE A CG  1 
ATOM   9143 C CD1 . PHE A 1 1234 ? 181.623 163.661 194.660 1.00 104.98 ? 1252 PHE A CD1 1 
ATOM   9144 C CD2 . PHE A 1 1234 ? 179.890 162.107 195.151 1.00 100.65 ? 1252 PHE A CD2 1 
ATOM   9145 C CE1 . PHE A 1 1234 ? 180.931 164.084 193.546 1.00 107.55 ? 1252 PHE A CE1 1 
ATOM   9146 C CE2 . PHE A 1 1234 ? 179.195 162.526 194.039 1.00 101.51 ? 1252 PHE A CE2 1 
ATOM   9147 C CZ  . PHE A 1 1234 ? 179.715 163.516 193.237 1.00 104.07 ? 1252 PHE A CZ  1 
ATOM   9148 N N   . ALA A 1 1235 ? 182.203 159.332 195.411 1.00 87.57  ? 1253 ALA A N   1 
ATOM   9149 C CA  . ALA A 1 1235 ? 181.805 158.410 194.359 1.00 83.59  ? 1253 ALA A CA  1 
ATOM   9150 C C   . ALA A 1 1235 ? 180.452 157.817 194.716 1.00 85.62  ? 1253 ALA A C   1 
ATOM   9151 O O   . ALA A 1 1235 ? 180.047 157.813 195.880 1.00 96.37  ? 1253 ALA A O   1 
ATOM   9152 C CB  . ALA A 1 1235 ? 182.836 157.295 194.159 1.00 78.01  ? 1253 ALA A CB  1 
ATOM   9153 N N   . ILE A 1 1236 ? 179.748 157.332 193.696 1.00 77.09  ? 1254 ILE A N   1 
ATOM   9154 C CA  . ILE A 1 1236 ? 178.447 156.693 193.854 1.00 73.23  ? 1254 ILE A CA  1 
ATOM   9155 C C   . ILE A 1 1236 ? 178.545 155.316 193.219 1.00 76.95  ? 1254 ILE A C   1 
ATOM   9156 O O   . ILE A 1 1236 ? 178.834 155.201 192.020 1.00 88.58  ? 1254 ILE A O   1 
ATOM   9157 C CB  . ILE A 1 1236 ? 177.324 157.526 193.216 1.00 68.01  ? 1254 ILE A CB  1 
ATOM   9158 C CG1 . ILE A 1 1236 ? 177.064 158.787 194.041 1.00 82.04  ? 1254 ILE A CG1 1 
ATOM   9159 C CG2 . ILE A 1 1236 ? 176.042 156.715 193.092 1.00 77.57  ? 1254 ILE A CG2 1 
ATOM   9160 C CD1 . ILE A 1 1236 ? 176.522 159.938 193.230 1.00 95.69  ? 1254 ILE A CD1 1 
ATOM   9161 N N   . CYS A 1 1237 ? 178.304 154.278 194.020 1.00 78.41  ? 1255 CYS A N   1 
ATOM   9162 C CA  . CYS A 1 1237 ? 178.415 152.891 193.588 1.00 80.63  ? 1255 CYS A CA  1 
ATOM   9163 C C   . CYS A 1 1237 ? 177.046 152.238 193.673 1.00 84.56  ? 1255 CYS A C   1 
ATOM   9164 O O   . CYS A 1 1237 ? 176.375 152.334 194.704 1.00 99.76  ? 1255 CYS A O   1 
ATOM   9165 C CB  . CYS A 1 1237 ? 179.423 152.131 194.450 1.00 90.08  ? 1255 CYS A CB  1 
ATOM   9166 S SG  . CYS A 1 1237 ? 179.581 150.387 194.026 1.00 122.27 ? 1255 CYS A SG  1 
ATOM   9167 N N   . GLN A 1 1238 ? 176.646 151.565 192.597 1.00 78.79  ? 1256 GLN A N   1 
ATOM   9168 C CA  . GLN A 1 1238 ? 175.312 150.995 192.459 1.00 84.33  ? 1256 GLN A CA  1 
ATOM   9169 C C   . GLN A 1 1238 ? 175.429 149.527 192.084 1.00 83.32  ? 1256 GLN A C   1 
ATOM   9170 O O   . GLN A 1 1238 ? 176.093 149.187 191.101 1.00 99.25  ? 1256 GLN A O   1 
ATOM   9171 C CB  . GLN A 1 1238 ? 174.513 151.751 191.394 1.00 90.32  ? 1256 GLN A CB  1 
ATOM   9172 C CG  . GLN A 1 1238 ? 173.036 151.406 191.336 1.00 101.12 ? 1256 GLN A CG  1 
ATOM   9173 C CD  . GLN A 1 1238 ? 172.366 151.973 190.103 1.00 114.36 ? 1256 GLN A CD  1 
ATOM   9174 O OE1 . GLN A 1 1238 ? 172.924 152.832 189.421 1.00 112.40 ? 1256 GLN A OE1 1 
ATOM   9175 N NE2 . GLN A 1 1238 ? 171.166 151.493 189.807 1.00 125.64 ? 1256 GLN A NE2 1 
ATOM   9176 N N   . LEU A 1 1239 ? 174.769 148.667 192.852 1.00 75.61  ? 1257 LEU A N   1 
ATOM   9177 C CA  . LEU A 1 1239 ? 174.708 147.236 192.584 1.00 75.40  ? 1257 LEU A CA  1 
ATOM   9178 C C   . LEU A 1 1239 ? 173.341 146.920 191.997 1.00 84.86  ? 1257 LEU A C   1 
ATOM   9179 O O   . LEU A 1 1239 ? 172.316 147.213 192.624 1.00 98.77  ? 1257 LEU A O   1 
ATOM   9180 C CB  . LEU A 1 1239 ? 174.950 146.429 193.859 1.00 75.18  ? 1257 LEU A CB  1 
ATOM   9181 C CG  . LEU A 1 1239 ? 174.738 144.915 193.769 1.00 76.92  ? 1257 LEU A CG  1 
ATOM   9182 C CD1 . LEU A 1 1239 ? 175.872 144.179 194.456 1.00 91.06  ? 1257 LEU A CD1 1 
ATOM   9183 C CD2 . LEU A 1 1239 ? 173.405 144.509 194.376 1.00 83.64  ? 1257 LEU A CD2 1 
ATOM   9184 N N   . ASN A 1 1240 ? 173.335 146.331 190.801 1.00 89.01  ? 1258 ASN A N   1 
ATOM   9185 C CA  . ASN A 1 1240 ? 172.125 145.917 190.103 1.00 92.70  ? 1258 ASN A CA  1 
ATOM   9186 C C   . ASN A 1 1240 ? 172.104 144.400 190.005 1.00 99.17  ? 1258 ASN A C   1 
ATOM   9187 O O   . ASN A 1 1240 ? 173.128 143.779 189.695 1.00 108.94 ? 1258 ASN A O   1 
ATOM   9188 C CB  . ASN A 1 1240 ? 172.058 146.527 188.702 1.00 86.84  ? 1258 ASN A CB  1 
ATOM   9189 C CG  . ASN A 1 1240 ? 172.626 147.926 188.649 1.00 94.92  ? 1258 ASN A CG  1 
ATOM   9190 O OD1 . ASN A 1 1240 ? 172.469 148.707 189.584 1.00 101.13 ? 1258 ASN A OD1 1 
ATOM   9191 N ND2 . ASN A 1 1240 ? 173.290 148.254 187.548 1.00 100.63 ? 1258 ASN A ND2 1 
ATOM   9192 N N   . VAL A 1 1241 ? 170.944 143.810 190.278 1.00 97.89  ? 1259 VAL A N   1 
ATOM   9193 C CA  . VAL A 1 1241 ? 170.742 142.368 190.209 1.00 101.39 ? 1259 VAL A CA  1 
ATOM   9194 C C   . VAL A 1 1241 ? 169.493 142.122 189.380 1.00 107.37 ? 1259 VAL A C   1 
ATOM   9195 O O   . VAL A 1 1241 ? 168.412 142.615 189.723 1.00 117.57 ? 1259 VAL A O   1 
ATOM   9196 C CB  . VAL A 1 1241 ? 170.601 141.740 191.605 1.00 105.74 ? 1259 VAL A CB  1 
ATOM   9197 C CG1 . VAL A 1 1241 ? 170.161 140.285 191.501 1.00 118.19 ? 1259 VAL A CG1 1 
ATOM   9198 C CG2 . VAL A 1 1241 ? 171.907 141.854 192.370 1.00 106.38 ? 1259 VAL A CG2 1 
ATOM   9199 N N   . VAL A 1 1242 ? 169.637 141.357 188.301 1.00 105.23 ? 1260 VAL A N   1 
ATOM   9200 C CA  . VAL A 1 1242 ? 168.538 141.015 187.405 1.00 110.46 ? 1260 VAL A CA  1 
ATOM   9201 C C   . VAL A 1 1242 ? 168.347 139.510 187.464 1.00 115.93 ? 1260 VAL A C   1 
ATOM   9202 O O   . VAL A 1 1242 ? 169.321 138.756 187.367 1.00 120.49 ? 1260 VAL A O   1 
ATOM   9203 C CB  . VAL A 1 1242 ? 168.817 141.476 185.962 1.00 110.97 ? 1260 VAL A CB  1 
ATOM   9204 C CG1 . VAL A 1 1242 ? 167.641 141.128 185.052 1.00 123.79 ? 1260 VAL A CG1 1 
ATOM   9205 C CG2 . VAL A 1 1242 ? 169.115 142.972 185.928 1.00 110.30 ? 1260 VAL A CG2 1 
ATOM   9206 N N   . TYR A 1 1243 ? 167.102 139.072 187.634 1.00 115.86 ? 1261 TYR A N   1 
ATOM   9207 C CA  . TYR A 1 1243 ? 166.811 137.647 187.715 1.00 122.27 ? 1261 TYR A CA  1 
ATOM   9208 C C   . TYR A 1 1243 ? 165.417 137.399 187.159 1.00 129.87 ? 1261 TYR A C   1 
ATOM   9209 O O   . TYR A 1 1243 ? 164.730 138.323 186.717 1.00 137.14 ? 1261 TYR A O   1 
ATOM   9210 C CB  . TYR A 1 1243 ? 166.954 137.139 189.154 1.00 124.34 ? 1261 TYR A CB  1 
ATOM   9211 C CG  . TYR A 1 1243 ? 166.071 137.836 190.162 1.00 124.56 ? 1261 TYR A CG  1 
ATOM   9212 C CD1 . TYR A 1 1243 ? 166.465 139.028 190.752 1.00 124.09 ? 1261 TYR A CD1 1 
ATOM   9213 C CD2 . TYR A 1 1243 ? 164.854 137.290 190.541 1.00 134.80 ? 1261 TYR A CD2 1 
ATOM   9214 C CE1 . TYR A 1 1243 ? 165.665 139.664 191.679 1.00 130.41 ? 1261 TYR A CE1 1 
ATOM   9215 C CE2 . TYR A 1 1243 ? 164.049 137.917 191.470 1.00 140.56 ? 1261 TYR A CE2 1 
ATOM   9216 C CZ  . TYR A 1 1243 ? 164.459 139.105 192.034 1.00 137.29 ? 1261 TYR A CZ  1 
ATOM   9217 O OH  . TYR A 1 1243 ? 163.661 139.737 192.959 1.00 137.25 ? 1261 TYR A OH  1 
ATOM   9218 N N   . ASN A 1 1244 ? 165.014 136.129 187.162 1.00 134.69 ? 1262 ASN A N   1 
ATOM   9219 C CA  . ASN A 1 1244 ? 163.713 135.700 186.671 1.00 146.24 ? 1262 ASN A CA  1 
ATOM   9220 C C   . ASN A 1 1244 ? 163.025 134.865 187.737 1.00 149.20 ? 1262 ASN A C   1 
ATOM   9221 O O   . ASN A 1 1244 ? 163.665 134.042 188.400 1.00 147.41 ? 1262 ASN A O   1 
ATOM   9222 C CB  . ASN A 1 1244 ? 163.843 134.888 185.379 1.00 151.70 ? 1262 ASN A CB  1 
ATOM   9223 C CG  . ASN A 1 1244 ? 164.026 135.762 184.154 1.00 154.27 ? 1262 ASN A CG  1 
ATOM   9224 O OD1 . ASN A 1 1244 ? 164.189 136.977 184.261 1.00 152.45 ? 1262 ASN A OD1 1 
ATOM   9225 N ND2 . ASN A 1 1244 ? 163.997 135.144 182.979 1.00 157.97 ? 1262 ASN A ND2 1 
ATOM   9226 N N   . VAL A 1 1245 ? 161.722 135.084 187.891 1.00 153.03 ? 1263 VAL A N   1 
ATOM   9227 C CA  . VAL A 1 1245 ? 160.906 134.362 188.857 1.00 155.61 ? 1263 VAL A CA  1 
ATOM   9228 C C   . VAL A 1 1245 ? 159.926 133.473 188.098 1.00 156.63 ? 1263 VAL A C   1 
ATOM   9229 O O   . VAL A 1 1245 ? 159.611 133.705 186.932 1.00 154.69 ? 1263 VAL A O   1 
ATOM   9230 C CB  . VAL A 1 1245 ? 160.164 135.315 189.817 1.00 153.07 ? 1263 VAL A CB  1 
ATOM   9231 C CG1 . VAL A 1 1245 ? 161.145 136.260 190.491 1.00 149.62 ? 1263 VAL A CG1 1 
ATOM   9232 C CG2 . VAL A 1 1245 ? 159.071 136.090 189.085 1.00 147.12 ? 1263 VAL A CG2 1 
ATOM   9233 N N   . LYS A 1 1246 ? 159.441 132.442 188.781 1.00 156.72 ? 1264 LYS A N   1 
ATOM   9234 C CA  . LYS A 1 1246 ? 158.533 131.477 188.171 1.00 153.60 ? 1264 LYS A CA  1 
ATOM   9235 C C   . LYS A 1 1246 ? 157.104 132.006 188.172 1.00 146.27 ? 1264 LYS A C   1 
ATOM   9236 O O   . LYS A 1 1246 ? 156.258 131.534 188.932 1.00 137.61 ? 1264 LYS A O   1 
ATOM   9237 C CB  . LYS A 1 1246 ? 158.600 130.137 188.907 1.00 149.69 ? 1264 LYS A CB  1 
ATOM   9238 C CG  . LYS A 1 1246 ? 159.964 129.445 188.828 1.00 149.91 ? 1264 LYS A CG  1 
ATOM   9239 C CD  . LYS A 1 1246 ? 160.228 128.532 190.023 1.00 154.25 ? 1264 LYS A CD  1 
ATOM   9240 C CE  . LYS A 1 1246 ? 161.704 128.184 190.142 1.00 156.01 ? 1264 LYS A CE  1 
ATOM   9241 N NZ  . LYS A 1 1246 ? 161.999 127.433 191.393 1.00 158.65 ? 1264 LYS A NZ  1 
HETATM 9242 C C1  . NAG B 2 .    ? 191.464 183.585 154.045 1.00 164.17 ? 1301 NAG A C1  1 
HETATM 9243 C C2  . NAG B 2 .    ? 191.573 182.170 153.452 1.00 176.19 ? 1301 NAG A C2  1 
HETATM 9244 C C3  . NAG B 2 .    ? 192.962 181.591 153.709 1.00 181.18 ? 1301 NAG A C3  1 
HETATM 9245 C C4  . NAG B 2 .    ? 194.042 182.549 153.229 1.00 179.39 ? 1301 NAG A C4  1 
HETATM 9246 C C5  . NAG B 2 .    ? 193.836 183.922 153.857 1.00 174.49 ? 1301 NAG A C5  1 
HETATM 9247 C C6  . NAG B 2 .    ? 194.813 184.957 153.351 1.00 177.50 ? 1301 NAG A C6  1 
HETATM 9248 C C7  . NAG B 2 .    ? 189.804 180.463 153.263 1.00 170.68 ? 1301 NAG A C7  1 
HETATM 9249 C C8  . NAG B 2 .    ? 188.805 179.636 154.017 1.00 155.80 ? 1301 NAG A C8  1 
HETATM 9250 N N2  . NAG B 2 .    ? 190.552 181.291 154.002 1.00 176.51 ? 1301 NAG A N2  1 
HETATM 9251 O O3  . NAG B 2 .    ? 193.085 180.344 153.035 1.00 187.36 ? 1301 NAG A O3  1 
HETATM 9252 O O4  . NAG B 2 .    ? 195.326 182.056 153.594 1.00 173.53 ? 1301 NAG A O4  1 
HETATM 9253 O O5  . NAG B 2 .    ? 192.523 184.403 153.539 1.00 168.64 ? 1301 NAG A O5  1 
HETATM 9254 O O6  . NAG B 2 .    ? 194.147 185.996 152.647 1.00 175.75 ? 1301 NAG A O6  1 
HETATM 9255 O O7  . NAG B 2 .    ? 189.926 180.381 152.045 1.00 170.23 ? 1301 NAG A O7  1 
HETATM 9256 C C1  . NAG C 2 .    ? 176.404 205.187 157.748 1.00 189.77 ? 1302 NAG A C1  1 
HETATM 9257 C C2  . NAG C 2 .    ? 174.959 205.640 157.547 1.00 192.11 ? 1302 NAG A C2  1 
HETATM 9258 C C3  . NAG C 2 .    ? 174.925 206.963 156.792 1.00 192.70 ? 1302 NAG A C3  1 
HETATM 9259 C C4  . NAG C 2 .    ? 175.791 207.998 157.497 1.00 194.30 ? 1302 NAG A C4  1 
HETATM 9260 C C5  . NAG C 2 .    ? 177.199 207.449 157.713 1.00 195.40 ? 1302 NAG A C5  1 
HETATM 9261 C C6  . NAG C 2 .    ? 178.074 208.376 158.524 1.00 195.10 ? 1302 NAG A C6  1 
HETATM 9262 C C7  . NAG C 2 .    ? 173.439 203.709 157.460 1.00 191.66 ? 1302 NAG A C7  1 
HETATM 9263 C C8  . NAG C 2 .    ? 172.710 202.749 156.567 1.00 184.96 ? 1302 NAG A C8  1 
HETATM 9264 N N2  . NAG C 2 .    ? 174.187 204.630 156.842 1.00 192.66 ? 1302 NAG A N2  1 
HETATM 9265 O O3  . NAG C 2 .    ? 173.582 207.427 156.713 1.00 190.26 ? 1302 NAG A O3  1 
HETATM 9266 O O4  . NAG C 2 .    ? 175.866 209.184 156.714 1.00 190.51 ? 1302 NAG A O4  1 
HETATM 9267 O O5  . NAG C 2 .    ? 177.137 206.207 158.429 1.00 193.02 ? 1302 NAG A O5  1 
HETATM 9268 O O6  . NAG C 2 .    ? 177.461 208.721 159.758 1.00 191.87 ? 1302 NAG A O6  1 
HETATM 9269 O O7  . NAG C 2 .    ? 173.354 203.650 158.683 1.00 189.53 ? 1302 NAG A O7  1 
HETATM 9270 C C1  . NAG D 2 .    ? 183.764 142.502 204.112 1.00 138.94 ? 1303 NAG A C1  1 
HETATM 9271 C C2  . NAG D 2 .    ? 183.710 140.981 204.001 1.00 142.13 ? 1303 NAG A C2  1 
HETATM 9272 C C3  . NAG D 2 .    ? 183.537 140.355 205.382 1.00 146.46 ? 1303 NAG A C3  1 
HETATM 9273 C C4  . NAG D 2 .    ? 184.623 140.852 206.326 1.00 149.91 ? 1303 NAG A C4  1 
HETATM 9274 C C5  . NAG D 2 .    ? 184.638 142.377 206.350 1.00 145.82 ? 1303 NAG A C5  1 
HETATM 9275 C C6  . NAG D 2 .    ? 185.771 142.942 207.174 1.00 146.36 ? 1303 NAG A C6  1 
HETATM 9276 C C7  . NAG D 2 .    ? 181.362 140.886 203.258 1.00 137.83 ? 1303 NAG A C7  1 
HETATM 9277 C C8  . NAG D 2 .    ? 180.418 140.347 202.226 1.00 131.03 ? 1303 NAG A C8  1 
HETATM 9278 N N2  . NAG D 2 .    ? 182.649 140.553 203.102 1.00 140.06 ? 1303 NAG A N2  1 
HETATM 9279 O O3  . NAG D 2 .    ? 183.603 138.938 205.268 1.00 146.33 ? 1303 NAG A O3  1 
HETATM 9280 O O4  . NAG D 2 .    ? 184.388 140.364 207.641 1.00 150.50 ? 1303 NAG A O4  1 
HETATM 9281 O O5  . NAG D 2 .    ? 184.805 142.883 205.018 1.00 137.30 ? 1303 NAG A O5  1 
HETATM 9282 O O6  . NAG D 2 .    ? 185.841 142.326 208.452 1.00 150.85 ? 1303 NAG A O6  1 
HETATM 9283 O O7  . NAG D 2 .    ? 180.976 141.586 204.188 1.00 136.46 ? 1303 NAG A O7  1 
HETATM 9284 C C1  . NAG E 2 .    ? 157.162 187.129 124.900 1.00 226.36 ? 1304 NAG A C1  1 
HETATM 9285 C C2  . NAG E 2 .    ? 158.044 186.850 123.679 1.00 225.10 ? 1304 NAG A C2  1 
HETATM 9286 C C3  . NAG E 2 .    ? 157.182 186.889 122.423 1.00 220.78 ? 1304 NAG A C3  1 
HETATM 9287 C C4  . NAG E 2 .    ? 156.021 185.915 122.543 1.00 226.61 ? 1304 NAG A C4  1 
HETATM 9288 C C5  . NAG E 2 .    ? 155.218 186.234 123.799 1.00 228.41 ? 1304 NAG A C5  1 
HETATM 9289 C C6  . NAG E 2 .    ? 154.126 185.226 124.061 1.00 229.92 ? 1304 NAG A C6  1 
HETATM 9290 C C7  . NAG E 2 .    ? 160.130 188.043 124.330 1.00 213.23 ? 1304 NAG A C7  1 
HETATM 9291 C C8  . NAG E 2 .    ? 160.635 189.453 124.313 1.00 204.67 ? 1304 NAG A C8  1 
HETATM 9292 N N2  . NAG E 2 .    ? 159.147 187.766 123.472 1.00 219.21 ? 1304 NAG A N2  1 
HETATM 9293 O O3  . NAG E 2 .    ? 157.985 186.588 121.291 1.00 206.95 ? 1304 NAG A O3  1 
HETATM 9294 O O4  . NAG E 2 .    ? 155.175 186.050 121.405 1.00 225.00 ? 1304 NAG A O4  1 
HETATM 9295 O O5  . NAG E 2 .    ? 156.080 186.212 124.953 1.00 230.60 ? 1304 NAG A O5  1 
HETATM 9296 O O6  . NAG E 2 .    ? 154.677 183.932 124.298 1.00 233.22 ? 1304 NAG A O6  1 
HETATM 9297 O O7  . NAG E 2 .    ? 160.598 187.194 125.081 1.00 211.66 ? 1304 NAG A O7  1 
HETATM 9298 C C1  . NAG F 2 .    ? 141.936 176.995 120.928 1.00 252.46 ? 1305 NAG A C1  1 
HETATM 9299 C C2  . NAG F 2 .    ? 140.679 177.793 121.363 1.00 247.70 ? 1305 NAG A C2  1 
HETATM 9300 C C3  . NAG F 2 .    ? 139.661 177.547 120.232 1.00 245.51 ? 1305 NAG A C3  1 
HETATM 9301 C C4  . NAG F 2 .    ? 140.204 177.766 118.812 1.00 248.00 ? 1305 NAG A C4  1 
HETATM 9302 C C5  . NAG F 2 .    ? 141.643 177.240 118.643 1.00 252.96 ? 1305 NAG A C5  1 
HETATM 9303 C C6  . NAG F 2 .    ? 142.357 177.713 117.399 1.00 250.83 ? 1305 NAG A C6  1 
HETATM 9304 C C7  . NAG F 2 .    ? 139.321 178.295 123.335 1.00 240.82 ? 1305 NAG A C7  1 
HETATM 9305 C C8  . NAG F 2 .    ? 138.699 177.664 124.545 1.00 236.26 ? 1305 NAG A C8  1 
HETATM 9306 N N2  . NAG F 2 .    ? 140.021 177.422 122.583 1.00 244.40 ? 1305 NAG A N2  1 
HETATM 9307 O O3  . NAG F 2 .    ? 138.533 178.359 120.427 1.00 238.56 ? 1305 NAG A O3  1 
HETATM 9308 O O4  . NAG F 2 .    ? 139.306 177.084 117.972 1.00 243.12 ? 1305 NAG A O4  1 
HETATM 9309 O O5  . NAG F 2 .    ? 142.426 177.609 119.761 1.00 254.34 ? 1305 NAG A O5  1 
HETATM 9310 O O6  . NAG F 2 .    ? 143.662 177.187 117.415 1.00 249.33 ? 1305 NAG A O6  1 
HETATM 9311 O O7  . NAG F 2 .    ? 139.178 179.482 123.069 1.00 239.15 ? 1305 NAG A O7  1 
# 
