data_9FWF
# 
_entry.id   9FWF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FWF         pdb_00009fwf 10.2210/pdb9fwf/pdb 
WWPDB D_1292139854 ?            ?                   
EMDB  EMD-50833    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-02-26 ? 
2  'EM metadata'     1 0 2025-02-26 ? 
3  'Additional map'  1 0 2025-02-26 1 
4  'Additional map'  1 0 2025-02-26 2 
5  'Additional map'  1 0 2025-02-26 3 
6  'Additional map'  1 0 2025-02-26 4 
7  'Half map'        1 0 2025-02-26 1 
8  'Half map'        1 0 2025-02-26 2 
9  Image             1 0 2025-02-26 ? 
10 Mask              1 0 2025-02-26 1 
11 'Primary map'     1 0 2025-02-26 ? 
12 'Structure model' 1 1 2025-03-05 ? 
13 'EM metadata'     1 1 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Additional map'  repository 'Initial release' ? ? 
4  4  'Additional map'  repository 'Initial release' ? ? 
5  5  'Additional map'  repository 'Initial release' ? ? 
6  6  'Additional map'  repository 'Initial release' ? ? 
7  7  'Half map'        repository 'Initial release' ? ? 
8  8  'Half map'        repository 'Initial release' ? ? 
9  9  Image             repository 'Initial release' ? ? 
10 10 Mask              repository 'Initial release' ? ? 
11 11 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 12 'Structure model' 'Data collection'      
2 12 'Structure model' 'Database references'  
3 13 'EM metadata'     'Database references'  
4 13 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 12 'Structure model' citation 
2 12 'Structure model' em_admin 
3 13 'EM metadata'     citation 
4 13 'EM metadata'     em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 12 'Structure model' '_citation.journal_volume' 
2 12 'Structure model' '_em_admin.last_update'    
3 13 'EM metadata'     '_citation.journal_volume' 
4 13 'EM metadata'     '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FWF 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus (T=4 VLP)' 
_pdbx_database_related.db_id          EMD-50833 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 D.J.Rowlands@leeds.ac.uk   David  Rowlands   J 'principal investigator/group leader' 0000-0002-4742-9272 
4 N.J.Stonehouse@leeds.ac.uk Nicola Stonehouse J 'principal investigator/group leader' 0000-0003-1146-5519 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fatema, K.'       1 0000-0002-6629-9928 
'Snowden, J.S.'    2 0000-0001-7857-0634 
'Watson, A.'       3 0000-0001-6710-7898 
'Sherry, L.'       4 0000-0002-4367-772X 
'Ranson, N.A.'     5 0000-0002-3640-5275 
'Stonehouse, N.J.' 6 0000-0003-1146-5519 
'Rowlands, D.J.'   7 0000-0002-4742-9272 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Int.J.Biol.Macromol. 
_citation.journal_id_ASTM           IJBMDR 
_citation.journal_id_CSD            0708 
_citation.journal_id_ISSN           0141-8130 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            305 
_citation.language                  ? 
_citation.page_first                141152 
_citation.page_last                 141152 
_citation.title                     
'A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.ijbiomac.2025.141152 
_citation.pdbx_database_id_PubMed   39961558 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fatema, K.'       1 ? 
primary 'Snowden, J.S.'    2 ? 
primary 'Watson, A.'       3 ? 
primary 'Sherry, L.'       4 ? 
primary 'Ranson, N.A.'     5 ? 
primary 'Stonehouse, N.J.' 6 ? 
primary 'Rowlands, D.J.'   7 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus' 
_entity.formula_weight             34171.977 
_entity.pdbx_number_of_molecules   4 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MASAATGVRAVPGNENSLEIEELARFAVDEHNKKENALLEFVRVVKAKEQIIIHENDADTMYYLTLEAKDGGKKKLYEAK
VWVKGIMDGLNKYNFKELQEFKPVGDAGGRMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSP
HHTALRQAILAWGELMTLATWVGNNLEFAGASDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVW
IRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MASAATGVRAVPGNENSLEIEELARFAVDEHNKKENALLEFVRVVKAKEQIIIHENDADTMYYLTLEAKDGGKKKLYEAK
VWVKGIMDGLNKYNFKELQEFKPVGDAGGRMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSP
HHTALRQAILAWGELMTLATWVGNNLEFAGASDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVW
IRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   SER n 
1 4   ALA n 
1 5   ALA n 
1 6   THR n 
1 7   GLY n 
1 8   VAL n 
1 9   ARG n 
1 10  ALA n 
1 11  VAL n 
1 12  PRO n 
1 13  GLY n 
1 14  ASN n 
1 15  GLU n 
1 16  ASN n 
1 17  SER n 
1 18  LEU n 
1 19  GLU n 
1 20  ILE n 
1 21  GLU n 
1 22  GLU n 
1 23  LEU n 
1 24  ALA n 
1 25  ARG n 
1 26  PHE n 
1 27  ALA n 
1 28  VAL n 
1 29  ASP n 
1 30  GLU n 
1 31  HIS n 
1 32  ASN n 
1 33  LYS n 
1 34  LYS n 
1 35  GLU n 
1 36  ASN n 
1 37  ALA n 
1 38  LEU n 
1 39  LEU n 
1 40  GLU n 
1 41  PHE n 
1 42  VAL n 
1 43  ARG n 
1 44  VAL n 
1 45  VAL n 
1 46  LYS n 
1 47  ALA n 
1 48  LYS n 
1 49  GLU n 
1 50  GLN n 
1 51  ILE n 
1 52  ILE n 
1 53  ILE n 
1 54  HIS n 
1 55  GLU n 
1 56  ASN n 
1 57  ASP n 
1 58  ALA n 
1 59  ASP n 
1 60  THR n 
1 61  MET n 
1 62  TYR n 
1 63  TYR n 
1 64  LEU n 
1 65  THR n 
1 66  LEU n 
1 67  GLU n 
1 68  ALA n 
1 69  LYS n 
1 70  ASP n 
1 71  GLY n 
1 72  GLY n 
1 73  LYS n 
1 74  LYS n 
1 75  LYS n 
1 76  LEU n 
1 77  TYR n 
1 78  GLU n 
1 79  ALA n 
1 80  LYS n 
1 81  VAL n 
1 82  TRP n 
1 83  VAL n 
1 84  LYS n 
1 85  GLY n 
1 86  ILE n 
1 87  MET n 
1 88  ASP n 
1 89  GLY n 
1 90  LEU n 
1 91  ASN n 
1 92  LYS n 
1 93  TYR n 
1 94  ASN n 
1 95  PHE n 
1 96  LYS n 
1 97  GLU n 
1 98  LEU n 
1 99  GLN n 
1 100 GLU n 
1 101 PHE n 
1 102 LYS n 
1 103 PRO n 
1 104 VAL n 
1 105 GLY n 
1 106 ASP n 
1 107 ALA n 
1 108 GLY n 
1 109 GLY n 
1 110 ARG n 
1 111 MET n 
1 112 ASP n 
1 113 ILE n 
1 114 ASP n 
1 115 PRO n 
1 116 TYR n 
1 117 LYS n 
1 118 GLU n 
1 119 PHE n 
1 120 GLY n 
1 121 ALA n 
1 122 THR n 
1 123 VAL n 
1 124 GLU n 
1 125 LEU n 
1 126 LEU n 
1 127 SER n 
1 128 PHE n 
1 129 LEU n 
1 130 PRO n 
1 131 SER n 
1 132 ASP n 
1 133 PHE n 
1 134 PHE n 
1 135 PRO n 
1 136 SER n 
1 137 VAL n 
1 138 ARG n 
1 139 ASP n 
1 140 LEU n 
1 141 LEU n 
1 142 ASP n 
1 143 THR n 
1 144 ALA n 
1 145 SER n 
1 146 ALA n 
1 147 LEU n 
1 148 TYR n 
1 149 ARG n 
1 150 GLU n 
1 151 ALA n 
1 152 LEU n 
1 153 GLU n 
1 154 SER n 
1 155 PRO n 
1 156 GLU n 
1 157 HIS n 
1 158 CYS n 
1 159 SER n 
1 160 PRO n 
1 161 HIS n 
1 162 HIS n 
1 163 THR n 
1 164 ALA n 
1 165 LEU n 
1 166 ARG n 
1 167 GLN n 
1 168 ALA n 
1 169 ILE n 
1 170 LEU n 
1 171 ALA n 
1 172 TRP n 
1 173 GLY n 
1 174 GLU n 
1 175 LEU n 
1 176 MET n 
1 177 THR n 
1 178 LEU n 
1 179 ALA n 
1 180 THR n 
1 181 TRP n 
1 182 VAL n 
1 183 GLY n 
1 184 ASN n 
1 185 ASN n 
1 186 LEU n 
1 187 GLU n 
1 188 PHE n 
1 189 ALA n 
1 190 GLY n 
1 191 ALA n 
1 192 SER n 
1 193 ASP n 
1 194 PRO n 
1 195 ALA n 
1 196 SER n 
1 197 ARG n 
1 198 ASP n 
1 199 LEU n 
1 200 VAL n 
1 201 VAL n 
1 202 ASN n 
1 203 TYR n 
1 204 VAL n 
1 205 ASN n 
1 206 THR n 
1 207 ASN n 
1 208 MET n 
1 209 GLY n 
1 210 LEU n 
1 211 LYS n 
1 212 ILE n 
1 213 ARG n 
1 214 GLN n 
1 215 LEU n 
1 216 LEU n 
1 217 TRP n 
1 218 PHE n 
1 219 HIS n 
1 220 ILE n 
1 221 SER n 
1 222 CYS n 
1 223 LEU n 
1 224 THR n 
1 225 PHE n 
1 226 GLY n 
1 227 ARG n 
1 228 GLU n 
1 229 THR n 
1 230 VAL n 
1 231 LEU n 
1 232 GLU n 
1 233 TYR n 
1 234 LEU n 
1 235 VAL n 
1 236 SER n 
1 237 PHE n 
1 238 GLY n 
1 239 VAL n 
1 240 TRP n 
1 241 ILE n 
1 242 ARG n 
1 243 THR n 
1 244 PRO n 
1 245 PRO n 
1 246 ALA n 
1 247 TYR n 
1 248 ARG n 
1 249 PRO n 
1 250 PRO n 
1 251 ASN n 
1 252 ALA n 
1 253 PRO n 
1 254 ILE n 
1 255 LEU n 
1 256 SER n 
1 257 THR n 
1 258 LEU n 
1 259 PRO n 
1 260 GLU n 
1 261 THR n 
1 262 THR n 
1 263 VAL n 
1 264 VAL n 
1 265 ARG n 
1 266 ARG n 
1 267 ARG n 
1 268 ASP n 
1 269 ARG n 
1 270 GLY n 
1 271 ARG n 
1 272 SER n 
1 273 PRO n 
1 274 ARG n 
1 275 ARG n 
1 276 ARG n 
1 277 THR n 
1 278 PRO n 
1 279 SER n 
1 280 PRO n 
1 281 ARG n 
1 282 ARG n 
1 283 ARG n 
1 284 ARG n 
1 285 SER n 
1 286 GLN n 
1 287 SER n 
1 288 PRO n 
1 289 ARG n 
1 290 ARG n 
1 291 ARG n 
1 292 ARG n 
1 293 SER n 
1 294 GLN n 
1 295 SER n 
1 296 ARG n 
1 297 GLU n 
1 298 SER n 
1 299 GLN n 
1 300 CYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   300 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'synthetic construct' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     32630 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   ALA 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   ?   ?   ?   A . n 
A 1 7   GLY 7   7   ?   ?   ?   A . n 
A 1 8   VAL 8   8   ?   ?   ?   A . n 
A 1 9   ARG 9   9   ?   ?   ?   A . n 
A 1 10  ALA 10  10  ?   ?   ?   A . n 
A 1 11  VAL 11  11  ?   ?   ?   A . n 
A 1 12  PRO 12  12  ?   ?   ?   A . n 
A 1 13  GLY 13  13  ?   ?   ?   A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  ASN 16  16  16  ASN ASN A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  GLU 19  19  19  GLU GLU A . n 
A 1 20  ILE 20  20  20  ILE ILE A . n 
A 1 21  GLU 21  21  21  GLU GLU A . n 
A 1 22  GLU 22  22  22  GLU GLU A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  ARG 25  25  25  ARG ARG A . n 
A 1 26  PHE 26  26  26  PHE PHE A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  HIS 31  31  31  HIS HIS A . n 
A 1 32  ASN 32  32  32  ASN ASN A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  LYS 34  34  34  LYS LYS A . n 
A 1 35  GLU 35  35  35  GLU GLU A . n 
A 1 36  ASN 36  36  36  ASN ASN A . n 
A 1 37  ALA 37  37  37  ALA ALA A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  PHE 41  41  41  PHE PHE A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  VAL 45  45  45  VAL VAL A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  GLN 50  50  50  GLN GLN A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  ILE 53  53  ?   ?   ?   A . n 
A 1 54  HIS 54  54  ?   ?   ?   A . n 
A 1 55  GLU 55  55  ?   ?   ?   A . n 
A 1 56  ASN 56  56  ?   ?   ?   A . n 
A 1 57  ASP 57  57  ?   ?   ?   A . n 
A 1 58  ALA 58  58  ?   ?   ?   A . n 
A 1 59  ASP 59  59  59  ASP ASP A . n 
A 1 60  THR 60  60  60  THR THR A . n 
A 1 61  MET 61  61  61  MET MET A . n 
A 1 62  TYR 62  62  62  TYR TYR A . n 
A 1 63  TYR 63  63  63  TYR TYR A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  THR 65  65  65  THR THR A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  GLU 67  67  67  GLU GLU A . n 
A 1 68  ALA 68  68  68  ALA ALA A . n 
A 1 69  LYS 69  69  69  LYS LYS A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  LYS 74  74  74  LYS LYS A . n 
A 1 75  LYS 75  75  75  LYS LYS A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  TYR 77  77  77  TYR TYR A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  ALA 79  79  79  ALA ALA A . n 
A 1 80  LYS 80  80  80  LYS LYS A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  TRP 82  82  82  TRP TRP A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  LYS 84  84  ?   ?   ?   A . n 
A 1 85  GLY 85  85  ?   ?   ?   A . n 
A 1 86  ILE 86  86  ?   ?   ?   A . n 
A 1 87  MET 87  87  ?   ?   ?   A . n 
A 1 88  ASP 88  88  ?   ?   ?   A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  LEU 90  90  90  LEU LEU A . n 
A 1 91  ASN 91  91  91  ASN ASN A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  TYR 93  93  93  TYR TYR A . n 
A 1 94  ASN 94  94  94  ASN ASN A . n 
A 1 95  PHE 95  95  95  PHE PHE A . n 
A 1 96  LYS 96  96  96  LYS LYS A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  GLN 99  99  99  GLN GLN A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 PRO 103 103 103 PRO PRO A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 ALA 107 107 107 ALA ALA A . n 
A 1 108 GLY 108 108 108 GLY GLY A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ARG 110 110 110 ARG ARG A . n 
A 1 111 MET 111 111 111 MET MET A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 ILE 113 113 113 ILE ILE A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 LYS 117 117 117 LYS LYS A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 THR 122 122 122 THR THR A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 SER 127 127 127 SER SER A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 PHE 133 133 133 PHE PHE A . n 
A 1 134 PHE 134 134 134 PHE PHE A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 SER 136 136 136 SER SER A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 ARG 138 138 138 ARG ARG A . n 
A 1 139 ASP 139 139 139 ASP ASP A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ASP 142 142 142 ASP ASP A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 TYR 148 148 148 TYR TYR A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 GLU 150 150 150 GLU GLU A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 PRO 155 155 155 PRO PRO A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 CYS 158 158 158 CYS CYS A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 PRO 160 160 160 PRO PRO A . n 
A 1 161 HIS 161 161 161 HIS HIS A . n 
A 1 162 HIS 162 162 162 HIS HIS A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 ARG 166 166 166 ARG ARG A . n 
A 1 167 GLN 167 167 167 GLN GLN A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 ILE 169 169 169 ILE ILE A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 TRP 172 172 172 TRP TRP A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 LEU 175 175 175 LEU LEU A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 THR 177 177 177 THR THR A . n 
A 1 178 LEU 178 178 178 LEU LEU A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 THR 180 180 180 THR THR A . n 
A 1 181 TRP 181 181 181 TRP TRP A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 ASN 184 184 184 ASN ASN A . n 
A 1 185 ASN 185 185 185 ASN ASN A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 GLU 187 187 ?   ?   ?   A . n 
A 1 188 PHE 188 188 ?   ?   ?   A . n 
A 1 189 ALA 189 189 ?   ?   ?   A . n 
A 1 190 GLY 190 190 ?   ?   ?   A . n 
A 1 191 ALA 191 191 ?   ?   ?   A . n 
A 1 192 SER 192 192 ?   ?   ?   A . n 
A 1 193 ASP 193 193 ?   ?   ?   A . n 
A 1 194 PRO 194 194 ?   ?   ?   A . n 
A 1 195 ALA 195 195 ?   ?   ?   A . n 
A 1 196 SER 196 196 ?   ?   ?   A . n 
A 1 197 ARG 197 197 ?   ?   ?   A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 VAL 200 200 200 VAL VAL A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 ASN 202 202 202 ASN ASN A . n 
A 1 203 TYR 203 203 203 TYR TYR A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 ASN 205 205 205 ASN ASN A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ASN 207 207 207 ASN ASN A . n 
A 1 208 MET 208 208 208 MET MET A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 ILE 212 212 212 ILE ILE A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 GLN 214 214 214 GLN GLN A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 TRP 217 217 217 TRP TRP A . n 
A 1 218 PHE 218 218 218 PHE PHE A . n 
A 1 219 HIS 219 219 219 HIS HIS A . n 
A 1 220 ILE 220 220 220 ILE ILE A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 CYS 222 222 222 CYS CYS A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 PHE 225 225 225 PHE PHE A . n 
A 1 226 GLY 226 226 226 GLY GLY A . n 
A 1 227 ARG 227 227 227 ARG ARG A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 TYR 233 233 233 TYR TYR A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 PHE 237 237 237 PHE PHE A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 TRP 240 240 240 TRP TRP A . n 
A 1 241 ILE 241 241 241 ILE ILE A . n 
A 1 242 ARG 242 242 242 ARG ARG A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 PRO 244 244 244 PRO PRO A . n 
A 1 245 PRO 245 245 245 PRO PRO A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 ARG 248 248 248 ARG ARG A . n 
A 1 249 PRO 249 249 249 PRO PRO A . n 
A 1 250 PRO 250 250 250 PRO PRO A . n 
A 1 251 ASN 251 251 251 ASN ASN A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 PRO 253 253 253 PRO PRO A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 PRO 259 259 ?   ?   ?   A . n 
A 1 260 GLU 260 260 ?   ?   ?   A . n 
A 1 261 THR 261 261 ?   ?   ?   A . n 
A 1 262 THR 262 262 ?   ?   ?   A . n 
A 1 263 VAL 263 263 ?   ?   ?   A . n 
A 1 264 VAL 264 264 ?   ?   ?   A . n 
A 1 265 ARG 265 265 ?   ?   ?   A . n 
A 1 266 ARG 266 266 ?   ?   ?   A . n 
A 1 267 ARG 267 267 ?   ?   ?   A . n 
A 1 268 ASP 268 268 ?   ?   ?   A . n 
A 1 269 ARG 269 269 ?   ?   ?   A . n 
A 1 270 GLY 270 270 ?   ?   ?   A . n 
A 1 271 ARG 271 271 ?   ?   ?   A . n 
A 1 272 SER 272 272 ?   ?   ?   A . n 
A 1 273 PRO 273 273 ?   ?   ?   A . n 
A 1 274 ARG 274 274 ?   ?   ?   A . n 
A 1 275 ARG 275 275 ?   ?   ?   A . n 
A 1 276 ARG 276 276 ?   ?   ?   A . n 
A 1 277 THR 277 277 ?   ?   ?   A . n 
A 1 278 PRO 278 278 ?   ?   ?   A . n 
A 1 279 SER 279 279 ?   ?   ?   A . n 
A 1 280 PRO 280 280 ?   ?   ?   A . n 
A 1 281 ARG 281 281 ?   ?   ?   A . n 
A 1 282 ARG 282 282 ?   ?   ?   A . n 
A 1 283 ARG 283 283 ?   ?   ?   A . n 
A 1 284 ARG 284 284 ?   ?   ?   A . n 
A 1 285 SER 285 285 ?   ?   ?   A . n 
A 1 286 GLN 286 286 ?   ?   ?   A . n 
A 1 287 SER 287 287 ?   ?   ?   A . n 
A 1 288 PRO 288 288 ?   ?   ?   A . n 
A 1 289 ARG 289 289 ?   ?   ?   A . n 
A 1 290 ARG 290 290 ?   ?   ?   A . n 
A 1 291 ARG 291 291 ?   ?   ?   A . n 
A 1 292 ARG 292 292 ?   ?   ?   A . n 
A 1 293 SER 293 293 ?   ?   ?   A . n 
A 1 294 GLN 294 294 ?   ?   ?   A . n 
A 1 295 SER 295 295 ?   ?   ?   A . n 
A 1 296 ARG 296 296 ?   ?   ?   A . n 
A 1 297 GLU 297 297 ?   ?   ?   A . n 
A 1 298 SER 298 298 ?   ?   ?   A . n 
A 1 299 GLN 299 299 ?   ?   ?   A . n 
A 1 300 CYS 300 300 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   ALA 5   5   ?   ?   ?   B . n 
B 1 6   THR 6   6   ?   ?   ?   B . n 
B 1 7   GLY 7   7   ?   ?   ?   B . n 
B 1 8   VAL 8   8   ?   ?   ?   B . n 
B 1 9   ARG 9   9   ?   ?   ?   B . n 
B 1 10  ALA 10  10  ?   ?   ?   B . n 
B 1 11  VAL 11  11  ?   ?   ?   B . n 
B 1 12  PRO 12  12  ?   ?   ?   B . n 
B 1 13  GLY 13  13  ?   ?   ?   B . n 
B 1 14  ASN 14  14  14  ASN ASN B . n 
B 1 15  GLU 15  15  15  GLU GLU B . n 
B 1 16  ASN 16  16  16  ASN ASN B . n 
B 1 17  SER 17  17  17  SER SER B . n 
B 1 18  LEU 18  18  18  LEU LEU B . n 
B 1 19  GLU 19  19  19  GLU GLU B . n 
B 1 20  ILE 20  20  20  ILE ILE B . n 
B 1 21  GLU 21  21  21  GLU GLU B . n 
B 1 22  GLU 22  22  22  GLU GLU B . n 
B 1 23  LEU 23  23  23  LEU LEU B . n 
B 1 24  ALA 24  24  24  ALA ALA B . n 
B 1 25  ARG 25  25  25  ARG ARG B . n 
B 1 26  PHE 26  26  26  PHE PHE B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  VAL 28  28  28  VAL VAL B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  HIS 31  31  31  HIS HIS B . n 
B 1 32  ASN 32  32  32  ASN ASN B . n 
B 1 33  LYS 33  33  33  LYS LYS B . n 
B 1 34  LYS 34  34  34  LYS LYS B . n 
B 1 35  GLU 35  35  35  GLU GLU B . n 
B 1 36  ASN 36  36  36  ASN ASN B . n 
B 1 37  ALA 37  37  37  ALA ALA B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  PHE 41  41  41  PHE PHE B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  ARG 43  43  43  ARG ARG B . n 
B 1 44  VAL 44  44  44  VAL VAL B . n 
B 1 45  VAL 45  45  45  VAL VAL B . n 
B 1 46  LYS 46  46  46  LYS LYS B . n 
B 1 47  ALA 47  47  47  ALA ALA B . n 
B 1 48  LYS 48  48  48  LYS LYS B . n 
B 1 49  GLU 49  49  49  GLU GLU B . n 
B 1 50  GLN 50  50  50  GLN GLN B . n 
B 1 51  ILE 51  51  51  ILE ILE B . n 
B 1 52  ILE 52  52  52  ILE ILE B . n 
B 1 53  ILE 53  53  ?   ?   ?   B . n 
B 1 54  HIS 54  54  ?   ?   ?   B . n 
B 1 55  GLU 55  55  ?   ?   ?   B . n 
B 1 56  ASN 56  56  ?   ?   ?   B . n 
B 1 57  ASP 57  57  ?   ?   ?   B . n 
B 1 58  ALA 58  58  ?   ?   ?   B . n 
B 1 59  ASP 59  59  59  ASP ASP B . n 
B 1 60  THR 60  60  60  THR THR B . n 
B 1 61  MET 61  61  61  MET MET B . n 
B 1 62  TYR 62  62  62  TYR TYR B . n 
B 1 63  TYR 63  63  63  TYR TYR B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  THR 65  65  65  THR THR B . n 
B 1 66  LEU 66  66  66  LEU LEU B . n 
B 1 67  GLU 67  67  67  GLU GLU B . n 
B 1 68  ALA 68  68  68  ALA ALA B . n 
B 1 69  LYS 69  69  69  LYS LYS B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  LYS 73  73  73  LYS LYS B . n 
B 1 74  LYS 74  74  74  LYS LYS B . n 
B 1 75  LYS 75  75  75  LYS LYS B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  TYR 77  77  77  TYR TYR B . n 
B 1 78  GLU 78  78  78  GLU GLU B . n 
B 1 79  ALA 79  79  79  ALA ALA B . n 
B 1 80  LYS 80  80  80  LYS LYS B . n 
B 1 81  VAL 81  81  81  VAL VAL B . n 
B 1 82  TRP 82  82  82  TRP TRP B . n 
B 1 83  VAL 83  83  83  VAL VAL B . n 
B 1 84  LYS 84  84  ?   ?   ?   B . n 
B 1 85  GLY 85  85  ?   ?   ?   B . n 
B 1 86  ILE 86  86  ?   ?   ?   B . n 
B 1 87  MET 87  87  ?   ?   ?   B . n 
B 1 88  ASP 88  88  ?   ?   ?   B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  LEU 90  90  90  LEU LEU B . n 
B 1 91  ASN 91  91  91  ASN ASN B . n 
B 1 92  LYS 92  92  92  LYS LYS B . n 
B 1 93  TYR 93  93  93  TYR TYR B . n 
B 1 94  ASN 94  94  94  ASN ASN B . n 
B 1 95  PHE 95  95  95  PHE PHE B . n 
B 1 96  LYS 96  96  96  LYS LYS B . n 
B 1 97  GLU 97  97  97  GLU GLU B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  GLN 99  99  99  GLN GLN B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 PHE 101 101 101 PHE PHE B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 PRO 103 103 103 PRO PRO B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 GLY 105 105 105 GLY GLY B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 ALA 107 107 107 ALA ALA B . n 
B 1 108 GLY 108 108 108 GLY GLY B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 ARG 110 110 110 ARG ARG B . n 
B 1 111 MET 111 111 111 MET MET B . n 
B 1 112 ASP 112 112 112 ASP ASP B . n 
B 1 113 ILE 113 113 113 ILE ILE B . n 
B 1 114 ASP 114 114 114 ASP ASP B . n 
B 1 115 PRO 115 115 115 PRO PRO B . n 
B 1 116 TYR 116 116 116 TYR TYR B . n 
B 1 117 LYS 117 117 117 LYS LYS B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 PHE 119 119 119 PHE PHE B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 THR 122 122 122 THR THR B . n 
B 1 123 VAL 123 123 123 VAL VAL B . n 
B 1 124 GLU 124 124 124 GLU GLU B . n 
B 1 125 LEU 125 125 125 LEU LEU B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 SER 127 127 127 SER SER B . n 
B 1 128 PHE 128 128 128 PHE PHE B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 PRO 130 130 130 PRO PRO B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 ASP 132 132 132 ASP ASP B . n 
B 1 133 PHE 133 133 133 PHE PHE B . n 
B 1 134 PHE 134 134 134 PHE PHE B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 SER 136 136 136 SER SER B . n 
B 1 137 VAL 137 137 137 VAL VAL B . n 
B 1 138 ARG 138 138 138 ARG ARG B . n 
B 1 139 ASP 139 139 139 ASP ASP B . n 
B 1 140 LEU 140 140 140 LEU LEU B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 ASP 142 142 142 ASP ASP B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 SER 145 145 145 SER SER B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 TYR 148 148 148 TYR TYR B . n 
B 1 149 ARG 149 149 149 ARG ARG B . n 
B 1 150 GLU 150 150 150 GLU GLU B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 LEU 152 152 152 LEU LEU B . n 
B 1 153 GLU 153 153 153 GLU GLU B . n 
B 1 154 SER 154 154 154 SER SER B . n 
B 1 155 PRO 155 155 155 PRO PRO B . n 
B 1 156 GLU 156 156 156 GLU GLU B . n 
B 1 157 HIS 157 157 157 HIS HIS B . n 
B 1 158 CYS 158 158 158 CYS CYS B . n 
B 1 159 SER 159 159 159 SER SER B . n 
B 1 160 PRO 160 160 160 PRO PRO B . n 
B 1 161 HIS 161 161 161 HIS HIS B . n 
B 1 162 HIS 162 162 162 HIS HIS B . n 
B 1 163 THR 163 163 163 THR THR B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 ARG 166 166 166 ARG ARG B . n 
B 1 167 GLN 167 167 167 GLN GLN B . n 
B 1 168 ALA 168 168 168 ALA ALA B . n 
B 1 169 ILE 169 169 169 ILE ILE B . n 
B 1 170 LEU 170 170 170 LEU LEU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 TRP 172 172 172 TRP TRP B . n 
B 1 173 GLY 173 173 173 GLY GLY B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 LEU 175 175 175 LEU LEU B . n 
B 1 176 MET 176 176 176 MET MET B . n 
B 1 177 THR 177 177 177 THR THR B . n 
B 1 178 LEU 178 178 178 LEU LEU B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 THR 180 180 180 THR THR B . n 
B 1 181 TRP 181 181 181 TRP TRP B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 ASN 184 184 184 ASN ASN B . n 
B 1 185 ASN 185 185 ?   ?   ?   B . n 
B 1 186 LEU 186 186 ?   ?   ?   B . n 
B 1 187 GLU 187 187 ?   ?   ?   B . n 
B 1 188 PHE 188 188 ?   ?   ?   B . n 
B 1 189 ALA 189 189 ?   ?   ?   B . n 
B 1 190 GLY 190 190 ?   ?   ?   B . n 
B 1 191 ALA 191 191 ?   ?   ?   B . n 
B 1 192 SER 192 192 ?   ?   ?   B . n 
B 1 193 ASP 193 193 ?   ?   ?   B . n 
B 1 194 PRO 194 194 194 PRO PRO B . n 
B 1 195 ALA 195 195 195 ALA ALA B . n 
B 1 196 SER 196 196 196 SER SER B . n 
B 1 197 ARG 197 197 197 ARG ARG B . n 
B 1 198 ASP 198 198 198 ASP ASP B . n 
B 1 199 LEU 199 199 199 LEU LEU B . n 
B 1 200 VAL 200 200 200 VAL VAL B . n 
B 1 201 VAL 201 201 201 VAL VAL B . n 
B 1 202 ASN 202 202 202 ASN ASN B . n 
B 1 203 TYR 203 203 203 TYR TYR B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 ASN 205 205 205 ASN ASN B . n 
B 1 206 THR 206 206 206 THR THR B . n 
B 1 207 ASN 207 207 207 ASN ASN B . n 
B 1 208 MET 208 208 208 MET MET B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 LEU 210 210 210 LEU LEU B . n 
B 1 211 LYS 211 211 211 LYS LYS B . n 
B 1 212 ILE 212 212 212 ILE ILE B . n 
B 1 213 ARG 213 213 213 ARG ARG B . n 
B 1 214 GLN 214 214 214 GLN GLN B . n 
B 1 215 LEU 215 215 215 LEU LEU B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 TRP 217 217 217 TRP TRP B . n 
B 1 218 PHE 218 218 218 PHE PHE B . n 
B 1 219 HIS 219 219 219 HIS HIS B . n 
B 1 220 ILE 220 220 220 ILE ILE B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 CYS 222 222 222 CYS CYS B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 PHE 225 225 225 PHE PHE B . n 
B 1 226 GLY 226 226 226 GLY GLY B . n 
B 1 227 ARG 227 227 227 ARG ARG B . n 
B 1 228 GLU 228 228 228 GLU GLU B . n 
B 1 229 THR 229 229 229 THR THR B . n 
B 1 230 VAL 230 230 230 VAL VAL B . n 
B 1 231 LEU 231 231 231 LEU LEU B . n 
B 1 232 GLU 232 232 232 GLU GLU B . n 
B 1 233 TYR 233 233 233 TYR TYR B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 PHE 237 237 237 PHE PHE B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 TRP 240 240 240 TRP TRP B . n 
B 1 241 ILE 241 241 241 ILE ILE B . n 
B 1 242 ARG 242 242 242 ARG ARG B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 PRO 244 244 244 PRO PRO B . n 
B 1 245 PRO 245 245 245 PRO PRO B . n 
B 1 246 ALA 246 246 246 ALA ALA B . n 
B 1 247 TYR 247 247 247 TYR TYR B . n 
B 1 248 ARG 248 248 248 ARG ARG B . n 
B 1 249 PRO 249 249 249 PRO PRO B . n 
B 1 250 PRO 250 250 250 PRO PRO B . n 
B 1 251 ASN 251 251 251 ASN ASN B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 PRO 253 253 253 PRO PRO B . n 
B 1 254 ILE 254 254 254 ILE ILE B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 SER 256 256 256 SER SER B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 LEU 258 258 258 LEU LEU B . n 
B 1 259 PRO 259 259 ?   ?   ?   B . n 
B 1 260 GLU 260 260 ?   ?   ?   B . n 
B 1 261 THR 261 261 ?   ?   ?   B . n 
B 1 262 THR 262 262 ?   ?   ?   B . n 
B 1 263 VAL 263 263 ?   ?   ?   B . n 
B 1 264 VAL 264 264 ?   ?   ?   B . n 
B 1 265 ARG 265 265 ?   ?   ?   B . n 
B 1 266 ARG 266 266 ?   ?   ?   B . n 
B 1 267 ARG 267 267 ?   ?   ?   B . n 
B 1 268 ASP 268 268 ?   ?   ?   B . n 
B 1 269 ARG 269 269 ?   ?   ?   B . n 
B 1 270 GLY 270 270 ?   ?   ?   B . n 
B 1 271 ARG 271 271 ?   ?   ?   B . n 
B 1 272 SER 272 272 ?   ?   ?   B . n 
B 1 273 PRO 273 273 ?   ?   ?   B . n 
B 1 274 ARG 274 274 ?   ?   ?   B . n 
B 1 275 ARG 275 275 ?   ?   ?   B . n 
B 1 276 ARG 276 276 ?   ?   ?   B . n 
B 1 277 THR 277 277 ?   ?   ?   B . n 
B 1 278 PRO 278 278 ?   ?   ?   B . n 
B 1 279 SER 279 279 ?   ?   ?   B . n 
B 1 280 PRO 280 280 ?   ?   ?   B . n 
B 1 281 ARG 281 281 ?   ?   ?   B . n 
B 1 282 ARG 282 282 ?   ?   ?   B . n 
B 1 283 ARG 283 283 ?   ?   ?   B . n 
B 1 284 ARG 284 284 ?   ?   ?   B . n 
B 1 285 SER 285 285 ?   ?   ?   B . n 
B 1 286 GLN 286 286 ?   ?   ?   B . n 
B 1 287 SER 287 287 ?   ?   ?   B . n 
B 1 288 PRO 288 288 ?   ?   ?   B . n 
B 1 289 ARG 289 289 ?   ?   ?   B . n 
B 1 290 ARG 290 290 ?   ?   ?   B . n 
B 1 291 ARG 291 291 ?   ?   ?   B . n 
B 1 292 ARG 292 292 ?   ?   ?   B . n 
B 1 293 SER 293 293 ?   ?   ?   B . n 
B 1 294 GLN 294 294 ?   ?   ?   B . n 
B 1 295 SER 295 295 ?   ?   ?   B . n 
B 1 296 ARG 296 296 ?   ?   ?   B . n 
B 1 297 GLU 297 297 ?   ?   ?   B . n 
B 1 298 SER 298 298 ?   ?   ?   B . n 
B 1 299 GLN 299 299 ?   ?   ?   B . n 
B 1 300 CYS 300 300 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   ?   ?   ?   C . n 
C 1 3   SER 3   3   ?   ?   ?   C . n 
C 1 4   ALA 4   4   ?   ?   ?   C . n 
C 1 5   ALA 5   5   ?   ?   ?   C . n 
C 1 6   THR 6   6   ?   ?   ?   C . n 
C 1 7   GLY 7   7   ?   ?   ?   C . n 
C 1 8   VAL 8   8   ?   ?   ?   C . n 
C 1 9   ARG 9   9   ?   ?   ?   C . n 
C 1 10  ALA 10  10  ?   ?   ?   C . n 
C 1 11  VAL 11  11  ?   ?   ?   C . n 
C 1 12  PRO 12  12  ?   ?   ?   C . n 
C 1 13  GLY 13  13  ?   ?   ?   C . n 
C 1 14  ASN 14  14  14  ASN ASN C . n 
C 1 15  GLU 15  15  15  GLU GLU C . n 
C 1 16  ASN 16  16  16  ASN ASN C . n 
C 1 17  SER 17  17  17  SER SER C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  GLU 19  19  19  GLU GLU C . n 
C 1 20  ILE 20  20  20  ILE ILE C . n 
C 1 21  GLU 21  21  21  GLU GLU C . n 
C 1 22  GLU 22  22  22  GLU GLU C . n 
C 1 23  LEU 23  23  23  LEU LEU C . n 
C 1 24  ALA 24  24  24  ALA ALA C . n 
C 1 25  ARG 25  25  25  ARG ARG C . n 
C 1 26  PHE 26  26  26  PHE PHE C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  VAL 28  28  28  VAL VAL C . n 
C 1 29  ASP 29  29  29  ASP ASP C . n 
C 1 30  GLU 30  30  30  GLU GLU C . n 
C 1 31  HIS 31  31  31  HIS HIS C . n 
C 1 32  ASN 32  32  32  ASN ASN C . n 
C 1 33  LYS 33  33  33  LYS LYS C . n 
C 1 34  LYS 34  34  34  LYS LYS C . n 
C 1 35  GLU 35  35  35  GLU GLU C . n 
C 1 36  ASN 36  36  36  ASN ASN C . n 
C 1 37  ALA 37  37  37  ALA ALA C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  LEU 39  39  39  LEU LEU C . n 
C 1 40  GLU 40  40  40  GLU GLU C . n 
C 1 41  PHE 41  41  41  PHE PHE C . n 
C 1 42  VAL 42  42  42  VAL VAL C . n 
C 1 43  ARG 43  43  43  ARG ARG C . n 
C 1 44  VAL 44  44  44  VAL VAL C . n 
C 1 45  VAL 45  45  45  VAL VAL C . n 
C 1 46  LYS 46  46  46  LYS LYS C . n 
C 1 47  ALA 47  47  47  ALA ALA C . n 
C 1 48  LYS 48  48  48  LYS LYS C . n 
C 1 49  GLU 49  49  49  GLU GLU C . n 
C 1 50  GLN 50  50  50  GLN GLN C . n 
C 1 51  ILE 51  51  51  ILE ILE C . n 
C 1 52  ILE 52  52  52  ILE ILE C . n 
C 1 53  ILE 53  53  ?   ?   ?   C . n 
C 1 54  HIS 54  54  ?   ?   ?   C . n 
C 1 55  GLU 55  55  ?   ?   ?   C . n 
C 1 56  ASN 56  56  ?   ?   ?   C . n 
C 1 57  ASP 57  57  ?   ?   ?   C . n 
C 1 58  ALA 58  58  ?   ?   ?   C . n 
C 1 59  ASP 59  59  59  ASP ASP C . n 
C 1 60  THR 60  60  60  THR THR C . n 
C 1 61  MET 61  61  61  MET MET C . n 
C 1 62  TYR 62  62  62  TYR TYR C . n 
C 1 63  TYR 63  63  63  TYR TYR C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  THR 65  65  65  THR THR C . n 
C 1 66  LEU 66  66  66  LEU LEU C . n 
C 1 67  GLU 67  67  67  GLU GLU C . n 
C 1 68  ALA 68  68  68  ALA ALA C . n 
C 1 69  LYS 69  69  69  LYS LYS C . n 
C 1 70  ASP 70  70  70  ASP ASP C . n 
C 1 71  GLY 71  71  71  GLY GLY C . n 
C 1 72  GLY 72  72  72  GLY GLY C . n 
C 1 73  LYS 73  73  73  LYS LYS C . n 
C 1 74  LYS 74  74  74  LYS LYS C . n 
C 1 75  LYS 75  75  75  LYS LYS C . n 
C 1 76  LEU 76  76  76  LEU LEU C . n 
C 1 77  TYR 77  77  77  TYR TYR C . n 
C 1 78  GLU 78  78  78  GLU GLU C . n 
C 1 79  ALA 79  79  79  ALA ALA C . n 
C 1 80  LYS 80  80  80  LYS LYS C . n 
C 1 81  VAL 81  81  81  VAL VAL C . n 
C 1 82  TRP 82  82  82  TRP TRP C . n 
C 1 83  VAL 83  83  83  VAL VAL C . n 
C 1 84  LYS 84  84  ?   ?   ?   C . n 
C 1 85  GLY 85  85  ?   ?   ?   C . n 
C 1 86  ILE 86  86  ?   ?   ?   C . n 
C 1 87  MET 87  87  ?   ?   ?   C . n 
C 1 88  ASP 88  88  ?   ?   ?   C . n 
C 1 89  GLY 89  89  89  GLY GLY C . n 
C 1 90  LEU 90  90  90  LEU LEU C . n 
C 1 91  ASN 91  91  91  ASN ASN C . n 
C 1 92  LYS 92  92  92  LYS LYS C . n 
C 1 93  TYR 93  93  93  TYR TYR C . n 
C 1 94  ASN 94  94  94  ASN ASN C . n 
C 1 95  PHE 95  95  95  PHE PHE C . n 
C 1 96  LYS 96  96  96  LYS LYS C . n 
C 1 97  GLU 97  97  97  GLU GLU C . n 
C 1 98  LEU 98  98  98  LEU LEU C . n 
C 1 99  GLN 99  99  99  GLN GLN C . n 
C 1 100 GLU 100 100 100 GLU GLU C . n 
C 1 101 PHE 101 101 101 PHE PHE C . n 
C 1 102 LYS 102 102 102 LYS LYS C . n 
C 1 103 PRO 103 103 103 PRO PRO C . n 
C 1 104 VAL 104 104 104 VAL VAL C . n 
C 1 105 GLY 105 105 105 GLY GLY C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 ALA 107 107 107 ALA ALA C . n 
C 1 108 GLY 108 108 108 GLY GLY C . n 
C 1 109 GLY 109 109 109 GLY GLY C . n 
C 1 110 ARG 110 110 110 ARG ARG C . n 
C 1 111 MET 111 111 111 MET MET C . n 
C 1 112 ASP 112 112 112 ASP ASP C . n 
C 1 113 ILE 113 113 113 ILE ILE C . n 
C 1 114 ASP 114 114 114 ASP ASP C . n 
C 1 115 PRO 115 115 115 PRO PRO C . n 
C 1 116 TYR 116 116 116 TYR TYR C . n 
C 1 117 LYS 117 117 117 LYS LYS C . n 
C 1 118 GLU 118 118 118 GLU GLU C . n 
C 1 119 PHE 119 119 119 PHE PHE C . n 
C 1 120 GLY 120 120 120 GLY GLY C . n 
C 1 121 ALA 121 121 121 ALA ALA C . n 
C 1 122 THR 122 122 122 THR THR C . n 
C 1 123 VAL 123 123 123 VAL VAL C . n 
C 1 124 GLU 124 124 124 GLU GLU C . n 
C 1 125 LEU 125 125 125 LEU LEU C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 SER 127 127 127 SER SER C . n 
C 1 128 PHE 128 128 128 PHE PHE C . n 
C 1 129 LEU 129 129 129 LEU LEU C . n 
C 1 130 PRO 130 130 130 PRO PRO C . n 
C 1 131 SER 131 131 131 SER SER C . n 
C 1 132 ASP 132 132 132 ASP ASP C . n 
C 1 133 PHE 133 133 133 PHE PHE C . n 
C 1 134 PHE 134 134 134 PHE PHE C . n 
C 1 135 PRO 135 135 135 PRO PRO C . n 
C 1 136 SER 136 136 136 SER SER C . n 
C 1 137 VAL 137 137 137 VAL VAL C . n 
C 1 138 ARG 138 138 138 ARG ARG C . n 
C 1 139 ASP 139 139 139 ASP ASP C . n 
C 1 140 LEU 140 140 140 LEU LEU C . n 
C 1 141 LEU 141 141 141 LEU LEU C . n 
C 1 142 ASP 142 142 142 ASP ASP C . n 
C 1 143 THR 143 143 143 THR THR C . n 
C 1 144 ALA 144 144 144 ALA ALA C . n 
C 1 145 SER 145 145 145 SER SER C . n 
C 1 146 ALA 146 146 146 ALA ALA C . n 
C 1 147 LEU 147 147 147 LEU LEU C . n 
C 1 148 TYR 148 148 148 TYR TYR C . n 
C 1 149 ARG 149 149 149 ARG ARG C . n 
C 1 150 GLU 150 150 150 GLU GLU C . n 
C 1 151 ALA 151 151 151 ALA ALA C . n 
C 1 152 LEU 152 152 152 LEU LEU C . n 
C 1 153 GLU 153 153 153 GLU GLU C . n 
C 1 154 SER 154 154 154 SER SER C . n 
C 1 155 PRO 155 155 155 PRO PRO C . n 
C 1 156 GLU 156 156 156 GLU GLU C . n 
C 1 157 HIS 157 157 157 HIS HIS C . n 
C 1 158 CYS 158 158 158 CYS CYS C . n 
C 1 159 SER 159 159 159 SER SER C . n 
C 1 160 PRO 160 160 160 PRO PRO C . n 
C 1 161 HIS 161 161 161 HIS HIS C . n 
C 1 162 HIS 162 162 162 HIS HIS C . n 
C 1 163 THR 163 163 163 THR THR C . n 
C 1 164 ALA 164 164 164 ALA ALA C . n 
C 1 165 LEU 165 165 165 LEU LEU C . n 
C 1 166 ARG 166 166 166 ARG ARG C . n 
C 1 167 GLN 167 167 167 GLN GLN C . n 
C 1 168 ALA 168 168 168 ALA ALA C . n 
C 1 169 ILE 169 169 169 ILE ILE C . n 
C 1 170 LEU 170 170 170 LEU LEU C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 TRP 172 172 172 TRP TRP C . n 
C 1 173 GLY 173 173 173 GLY GLY C . n 
C 1 174 GLU 174 174 174 GLU GLU C . n 
C 1 175 LEU 175 175 175 LEU LEU C . n 
C 1 176 MET 176 176 176 MET MET C . n 
C 1 177 THR 177 177 177 THR THR C . n 
C 1 178 LEU 178 178 178 LEU LEU C . n 
C 1 179 ALA 179 179 179 ALA ALA C . n 
C 1 180 THR 180 180 180 THR THR C . n 
C 1 181 TRP 181 181 181 TRP TRP C . n 
C 1 182 VAL 182 182 182 VAL VAL C . n 
C 1 183 GLY 183 183 183 GLY GLY C . n 
C 1 184 ASN 184 184 184 ASN ASN C . n 
C 1 185 ASN 185 185 185 ASN ASN C . n 
C 1 186 LEU 186 186 186 LEU LEU C . n 
C 1 187 GLU 187 187 ?   ?   ?   C . n 
C 1 188 PHE 188 188 ?   ?   ?   C . n 
C 1 189 ALA 189 189 ?   ?   ?   C . n 
C 1 190 GLY 190 190 ?   ?   ?   C . n 
C 1 191 ALA 191 191 ?   ?   ?   C . n 
C 1 192 SER 192 192 ?   ?   ?   C . n 
C 1 193 ASP 193 193 ?   ?   ?   C . n 
C 1 194 PRO 194 194 ?   ?   ?   C . n 
C 1 195 ALA 195 195 ?   ?   ?   C . n 
C 1 196 SER 196 196 ?   ?   ?   C . n 
C 1 197 ARG 197 197 ?   ?   ?   C . n 
C 1 198 ASP 198 198 198 ASP ASP C . n 
C 1 199 LEU 199 199 199 LEU LEU C . n 
C 1 200 VAL 200 200 200 VAL VAL C . n 
C 1 201 VAL 201 201 201 VAL VAL C . n 
C 1 202 ASN 202 202 202 ASN ASN C . n 
C 1 203 TYR 203 203 203 TYR TYR C . n 
C 1 204 VAL 204 204 204 VAL VAL C . n 
C 1 205 ASN 205 205 205 ASN ASN C . n 
C 1 206 THR 206 206 206 THR THR C . n 
C 1 207 ASN 207 207 207 ASN ASN C . n 
C 1 208 MET 208 208 208 MET MET C . n 
C 1 209 GLY 209 209 209 GLY GLY C . n 
C 1 210 LEU 210 210 210 LEU LEU C . n 
C 1 211 LYS 211 211 211 LYS LYS C . n 
C 1 212 ILE 212 212 212 ILE ILE C . n 
C 1 213 ARG 213 213 213 ARG ARG C . n 
C 1 214 GLN 214 214 214 GLN GLN C . n 
C 1 215 LEU 215 215 215 LEU LEU C . n 
C 1 216 LEU 216 216 216 LEU LEU C . n 
C 1 217 TRP 217 217 217 TRP TRP C . n 
C 1 218 PHE 218 218 218 PHE PHE C . n 
C 1 219 HIS 219 219 219 HIS HIS C . n 
C 1 220 ILE 220 220 220 ILE ILE C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 CYS 222 222 222 CYS CYS C . n 
C 1 223 LEU 223 223 223 LEU LEU C . n 
C 1 224 THR 224 224 224 THR THR C . n 
C 1 225 PHE 225 225 225 PHE PHE C . n 
C 1 226 GLY 226 226 226 GLY GLY C . n 
C 1 227 ARG 227 227 227 ARG ARG C . n 
C 1 228 GLU 228 228 228 GLU GLU C . n 
C 1 229 THR 229 229 229 THR THR C . n 
C 1 230 VAL 230 230 230 VAL VAL C . n 
C 1 231 LEU 231 231 231 LEU LEU C . n 
C 1 232 GLU 232 232 232 GLU GLU C . n 
C 1 233 TYR 233 233 233 TYR TYR C . n 
C 1 234 LEU 234 234 234 LEU LEU C . n 
C 1 235 VAL 235 235 235 VAL VAL C . n 
C 1 236 SER 236 236 236 SER SER C . n 
C 1 237 PHE 237 237 237 PHE PHE C . n 
C 1 238 GLY 238 238 238 GLY GLY C . n 
C 1 239 VAL 239 239 239 VAL VAL C . n 
C 1 240 TRP 240 240 240 TRP TRP C . n 
C 1 241 ILE 241 241 241 ILE ILE C . n 
C 1 242 ARG 242 242 242 ARG ARG C . n 
C 1 243 THR 243 243 243 THR THR C . n 
C 1 244 PRO 244 244 244 PRO PRO C . n 
C 1 245 PRO 245 245 245 PRO PRO C . n 
C 1 246 ALA 246 246 246 ALA ALA C . n 
C 1 247 TYR 247 247 247 TYR TYR C . n 
C 1 248 ARG 248 248 248 ARG ARG C . n 
C 1 249 PRO 249 249 249 PRO PRO C . n 
C 1 250 PRO 250 250 250 PRO PRO C . n 
C 1 251 ASN 251 251 251 ASN ASN C . n 
C 1 252 ALA 252 252 252 ALA ALA C . n 
C 1 253 PRO 253 253 253 PRO PRO C . n 
C 1 254 ILE 254 254 254 ILE ILE C . n 
C 1 255 LEU 255 255 255 LEU LEU C . n 
C 1 256 SER 256 256 256 SER SER C . n 
C 1 257 THR 257 257 257 THR THR C . n 
C 1 258 LEU 258 258 ?   ?   ?   C . n 
C 1 259 PRO 259 259 ?   ?   ?   C . n 
C 1 260 GLU 260 260 ?   ?   ?   C . n 
C 1 261 THR 261 261 ?   ?   ?   C . n 
C 1 262 THR 262 262 ?   ?   ?   C . n 
C 1 263 VAL 263 263 ?   ?   ?   C . n 
C 1 264 VAL 264 264 ?   ?   ?   C . n 
C 1 265 ARG 265 265 ?   ?   ?   C . n 
C 1 266 ARG 266 266 ?   ?   ?   C . n 
C 1 267 ARG 267 267 ?   ?   ?   C . n 
C 1 268 ASP 268 268 ?   ?   ?   C . n 
C 1 269 ARG 269 269 ?   ?   ?   C . n 
C 1 270 GLY 270 270 ?   ?   ?   C . n 
C 1 271 ARG 271 271 ?   ?   ?   C . n 
C 1 272 SER 272 272 ?   ?   ?   C . n 
C 1 273 PRO 273 273 ?   ?   ?   C . n 
C 1 274 ARG 274 274 ?   ?   ?   C . n 
C 1 275 ARG 275 275 ?   ?   ?   C . n 
C 1 276 ARG 276 276 ?   ?   ?   C . n 
C 1 277 THR 277 277 ?   ?   ?   C . n 
C 1 278 PRO 278 278 ?   ?   ?   C . n 
C 1 279 SER 279 279 ?   ?   ?   C . n 
C 1 280 PRO 280 280 ?   ?   ?   C . n 
C 1 281 ARG 281 281 ?   ?   ?   C . n 
C 1 282 ARG 282 282 ?   ?   ?   C . n 
C 1 283 ARG 283 283 ?   ?   ?   C . n 
C 1 284 ARG 284 284 ?   ?   ?   C . n 
C 1 285 SER 285 285 ?   ?   ?   C . n 
C 1 286 GLN 286 286 ?   ?   ?   C . n 
C 1 287 SER 287 287 ?   ?   ?   C . n 
C 1 288 PRO 288 288 ?   ?   ?   C . n 
C 1 289 ARG 289 289 ?   ?   ?   C . n 
C 1 290 ARG 290 290 ?   ?   ?   C . n 
C 1 291 ARG 291 291 ?   ?   ?   C . n 
C 1 292 ARG 292 292 ?   ?   ?   C . n 
C 1 293 SER 293 293 ?   ?   ?   C . n 
C 1 294 GLN 294 294 ?   ?   ?   C . n 
C 1 295 SER 295 295 ?   ?   ?   C . n 
C 1 296 ARG 296 296 ?   ?   ?   C . n 
C 1 297 GLU 297 297 ?   ?   ?   C . n 
C 1 298 SER 298 298 ?   ?   ?   C . n 
C 1 299 GLN 299 299 ?   ?   ?   C . n 
C 1 300 CYS 300 300 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   ALA 2   2   ?   ?   ?   D . n 
D 1 3   SER 3   3   ?   ?   ?   D . n 
D 1 4   ALA 4   4   ?   ?   ?   D . n 
D 1 5   ALA 5   5   ?   ?   ?   D . n 
D 1 6   THR 6   6   ?   ?   ?   D . n 
D 1 7   GLY 7   7   ?   ?   ?   D . n 
D 1 8   VAL 8   8   ?   ?   ?   D . n 
D 1 9   ARG 9   9   ?   ?   ?   D . n 
D 1 10  ALA 10  10  ?   ?   ?   D . n 
D 1 11  VAL 11  11  ?   ?   ?   D . n 
D 1 12  PRO 12  12  ?   ?   ?   D . n 
D 1 13  GLY 13  13  ?   ?   ?   D . n 
D 1 14  ASN 14  14  14  ASN ASN D . n 
D 1 15  GLU 15  15  15  GLU GLU D . n 
D 1 16  ASN 16  16  16  ASN ASN D . n 
D 1 17  SER 17  17  17  SER SER D . n 
D 1 18  LEU 18  18  18  LEU LEU D . n 
D 1 19  GLU 19  19  19  GLU GLU D . n 
D 1 20  ILE 20  20  20  ILE ILE D . n 
D 1 21  GLU 21  21  21  GLU GLU D . n 
D 1 22  GLU 22  22  22  GLU GLU D . n 
D 1 23  LEU 23  23  23  LEU LEU D . n 
D 1 24  ALA 24  24  24  ALA ALA D . n 
D 1 25  ARG 25  25  25  ARG ARG D . n 
D 1 26  PHE 26  26  26  PHE PHE D . n 
D 1 27  ALA 27  27  27  ALA ALA D . n 
D 1 28  VAL 28  28  28  VAL VAL D . n 
D 1 29  ASP 29  29  29  ASP ASP D . n 
D 1 30  GLU 30  30  30  GLU GLU D . n 
D 1 31  HIS 31  31  31  HIS HIS D . n 
D 1 32  ASN 32  32  32  ASN ASN D . n 
D 1 33  LYS 33  33  33  LYS LYS D . n 
D 1 34  LYS 34  34  34  LYS LYS D . n 
D 1 35  GLU 35  35  35  GLU GLU D . n 
D 1 36  ASN 36  36  36  ASN ASN D . n 
D 1 37  ALA 37  37  37  ALA ALA D . n 
D 1 38  LEU 38  38  38  LEU LEU D . n 
D 1 39  LEU 39  39  39  LEU LEU D . n 
D 1 40  GLU 40  40  40  GLU GLU D . n 
D 1 41  PHE 41  41  41  PHE PHE D . n 
D 1 42  VAL 42  42  42  VAL VAL D . n 
D 1 43  ARG 43  43  43  ARG ARG D . n 
D 1 44  VAL 44  44  44  VAL VAL D . n 
D 1 45  VAL 45  45  45  VAL VAL D . n 
D 1 46  LYS 46  46  46  LYS LYS D . n 
D 1 47  ALA 47  47  47  ALA ALA D . n 
D 1 48  LYS 48  48  48  LYS LYS D . n 
D 1 49  GLU 49  49  49  GLU GLU D . n 
D 1 50  GLN 50  50  50  GLN GLN D . n 
D 1 51  ILE 51  51  51  ILE ILE D . n 
D 1 52  ILE 52  52  52  ILE ILE D . n 
D 1 53  ILE 53  53  ?   ?   ?   D . n 
D 1 54  HIS 54  54  ?   ?   ?   D . n 
D 1 55  GLU 55  55  ?   ?   ?   D . n 
D 1 56  ASN 56  56  ?   ?   ?   D . n 
D 1 57  ASP 57  57  ?   ?   ?   D . n 
D 1 58  ALA 58  58  ?   ?   ?   D . n 
D 1 59  ASP 59  59  59  ASP ASP D . n 
D 1 60  THR 60  60  60  THR THR D . n 
D 1 61  MET 61  61  61  MET MET D . n 
D 1 62  TYR 62  62  62  TYR TYR D . n 
D 1 63  TYR 63  63  63  TYR TYR D . n 
D 1 64  LEU 64  64  64  LEU LEU D . n 
D 1 65  THR 65  65  65  THR THR D . n 
D 1 66  LEU 66  66  66  LEU LEU D . n 
D 1 67  GLU 67  67  67  GLU GLU D . n 
D 1 68  ALA 68  68  68  ALA ALA D . n 
D 1 69  LYS 69  69  69  LYS LYS D . n 
D 1 70  ASP 70  70  70  ASP ASP D . n 
D 1 71  GLY 71  71  71  GLY GLY D . n 
D 1 72  GLY 72  72  72  GLY GLY D . n 
D 1 73  LYS 73  73  73  LYS LYS D . n 
D 1 74  LYS 74  74  74  LYS LYS D . n 
D 1 75  LYS 75  75  75  LYS LYS D . n 
D 1 76  LEU 76  76  76  LEU LEU D . n 
D 1 77  TYR 77  77  77  TYR TYR D . n 
D 1 78  GLU 78  78  78  GLU GLU D . n 
D 1 79  ALA 79  79  79  ALA ALA D . n 
D 1 80  LYS 80  80  80  LYS LYS D . n 
D 1 81  VAL 81  81  81  VAL VAL D . n 
D 1 82  TRP 82  82  82  TRP TRP D . n 
D 1 83  VAL 83  83  83  VAL VAL D . n 
D 1 84  LYS 84  84  ?   ?   ?   D . n 
D 1 85  GLY 85  85  ?   ?   ?   D . n 
D 1 86  ILE 86  86  ?   ?   ?   D . n 
D 1 87  MET 87  87  ?   ?   ?   D . n 
D 1 88  ASP 88  88  ?   ?   ?   D . n 
D 1 89  GLY 89  89  89  GLY GLY D . n 
D 1 90  LEU 90  90  90  LEU LEU D . n 
D 1 91  ASN 91  91  91  ASN ASN D . n 
D 1 92  LYS 92  92  92  LYS LYS D . n 
D 1 93  TYR 93  93  93  TYR TYR D . n 
D 1 94  ASN 94  94  94  ASN ASN D . n 
D 1 95  PHE 95  95  95  PHE PHE D . n 
D 1 96  LYS 96  96  96  LYS LYS D . n 
D 1 97  GLU 97  97  97  GLU GLU D . n 
D 1 98  LEU 98  98  98  LEU LEU D . n 
D 1 99  GLN 99  99  99  GLN GLN D . n 
D 1 100 GLU 100 100 100 GLU GLU D . n 
D 1 101 PHE 101 101 101 PHE PHE D . n 
D 1 102 LYS 102 102 102 LYS LYS D . n 
D 1 103 PRO 103 103 103 PRO PRO D . n 
D 1 104 VAL 104 104 104 VAL VAL D . n 
D 1 105 GLY 105 105 105 GLY GLY D . n 
D 1 106 ASP 106 106 106 ASP ASP D . n 
D 1 107 ALA 107 107 107 ALA ALA D . n 
D 1 108 GLY 108 108 108 GLY GLY D . n 
D 1 109 GLY 109 109 109 GLY GLY D . n 
D 1 110 ARG 110 110 110 ARG ARG D . n 
D 1 111 MET 111 111 111 MET MET D . n 
D 1 112 ASP 112 112 112 ASP ASP D . n 
D 1 113 ILE 113 113 113 ILE ILE D . n 
D 1 114 ASP 114 114 114 ASP ASP D . n 
D 1 115 PRO 115 115 115 PRO PRO D . n 
D 1 116 TYR 116 116 116 TYR TYR D . n 
D 1 117 LYS 117 117 117 LYS LYS D . n 
D 1 118 GLU 118 118 118 GLU GLU D . n 
D 1 119 PHE 119 119 119 PHE PHE D . n 
D 1 120 GLY 120 120 120 GLY GLY D . n 
D 1 121 ALA 121 121 121 ALA ALA D . n 
D 1 122 THR 122 122 122 THR THR D . n 
D 1 123 VAL 123 123 123 VAL VAL D . n 
D 1 124 GLU 124 124 124 GLU GLU D . n 
D 1 125 LEU 125 125 125 LEU LEU D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 SER 127 127 127 SER SER D . n 
D 1 128 PHE 128 128 128 PHE PHE D . n 
D 1 129 LEU 129 129 129 LEU LEU D . n 
D 1 130 PRO 130 130 130 PRO PRO D . n 
D 1 131 SER 131 131 131 SER SER D . n 
D 1 132 ASP 132 132 132 ASP ASP D . n 
D 1 133 PHE 133 133 133 PHE PHE D . n 
D 1 134 PHE 134 134 134 PHE PHE D . n 
D 1 135 PRO 135 135 135 PRO PRO D . n 
D 1 136 SER 136 136 136 SER SER D . n 
D 1 137 VAL 137 137 137 VAL VAL D . n 
D 1 138 ARG 138 138 138 ARG ARG D . n 
D 1 139 ASP 139 139 139 ASP ASP D . n 
D 1 140 LEU 140 140 140 LEU LEU D . n 
D 1 141 LEU 141 141 141 LEU LEU D . n 
D 1 142 ASP 142 142 142 ASP ASP D . n 
D 1 143 THR 143 143 143 THR THR D . n 
D 1 144 ALA 144 144 144 ALA ALA D . n 
D 1 145 SER 145 145 145 SER SER D . n 
D 1 146 ALA 146 146 146 ALA ALA D . n 
D 1 147 LEU 147 147 147 LEU LEU D . n 
D 1 148 TYR 148 148 148 TYR TYR D . n 
D 1 149 ARG 149 149 149 ARG ARG D . n 
D 1 150 GLU 150 150 150 GLU GLU D . n 
D 1 151 ALA 151 151 151 ALA ALA D . n 
D 1 152 LEU 152 152 152 LEU LEU D . n 
D 1 153 GLU 153 153 153 GLU GLU D . n 
D 1 154 SER 154 154 154 SER SER D . n 
D 1 155 PRO 155 155 155 PRO PRO D . n 
D 1 156 GLU 156 156 156 GLU GLU D . n 
D 1 157 HIS 157 157 157 HIS HIS D . n 
D 1 158 CYS 158 158 158 CYS CYS D . n 
D 1 159 SER 159 159 159 SER SER D . n 
D 1 160 PRO 160 160 160 PRO PRO D . n 
D 1 161 HIS 161 161 161 HIS HIS D . n 
D 1 162 HIS 162 162 162 HIS HIS D . n 
D 1 163 THR 163 163 163 THR THR D . n 
D 1 164 ALA 164 164 164 ALA ALA D . n 
D 1 165 LEU 165 165 165 LEU LEU D . n 
D 1 166 ARG 166 166 166 ARG ARG D . n 
D 1 167 GLN 167 167 167 GLN GLN D . n 
D 1 168 ALA 168 168 168 ALA ALA D . n 
D 1 169 ILE 169 169 169 ILE ILE D . n 
D 1 170 LEU 170 170 170 LEU LEU D . n 
D 1 171 ALA 171 171 171 ALA ALA D . n 
D 1 172 TRP 172 172 172 TRP TRP D . n 
D 1 173 GLY 173 173 173 GLY GLY D . n 
D 1 174 GLU 174 174 174 GLU GLU D . n 
D 1 175 LEU 175 175 175 LEU LEU D . n 
D 1 176 MET 176 176 176 MET MET D . n 
D 1 177 THR 177 177 177 THR THR D . n 
D 1 178 LEU 178 178 178 LEU LEU D . n 
D 1 179 ALA 179 179 179 ALA ALA D . n 
D 1 180 THR 180 180 180 THR THR D . n 
D 1 181 TRP 181 181 181 TRP TRP D . n 
D 1 182 VAL 182 182 182 VAL VAL D . n 
D 1 183 GLY 183 183 183 GLY GLY D . n 
D 1 184 ASN 184 184 184 ASN ASN D . n 
D 1 185 ASN 185 185 185 ASN ASN D . n 
D 1 186 LEU 186 186 ?   ?   ?   D . n 
D 1 187 GLU 187 187 ?   ?   ?   D . n 
D 1 188 PHE 188 188 ?   ?   ?   D . n 
D 1 189 ALA 189 189 ?   ?   ?   D . n 
D 1 190 GLY 190 190 ?   ?   ?   D . n 
D 1 191 ALA 191 191 ?   ?   ?   D . n 
D 1 192 SER 192 192 ?   ?   ?   D . n 
D 1 193 ASP 193 193 ?   ?   ?   D . n 
D 1 194 PRO 194 194 194 PRO PRO D . n 
D 1 195 ALA 195 195 195 ALA ALA D . n 
D 1 196 SER 196 196 196 SER SER D . n 
D 1 197 ARG 197 197 197 ARG ARG D . n 
D 1 198 ASP 198 198 198 ASP ASP D . n 
D 1 199 LEU 199 199 199 LEU LEU D . n 
D 1 200 VAL 200 200 200 VAL VAL D . n 
D 1 201 VAL 201 201 201 VAL VAL D . n 
D 1 202 ASN 202 202 202 ASN ASN D . n 
D 1 203 TYR 203 203 203 TYR TYR D . n 
D 1 204 VAL 204 204 204 VAL VAL D . n 
D 1 205 ASN 205 205 205 ASN ASN D . n 
D 1 206 THR 206 206 206 THR THR D . n 
D 1 207 ASN 207 207 207 ASN ASN D . n 
D 1 208 MET 208 208 208 MET MET D . n 
D 1 209 GLY 209 209 209 GLY GLY D . n 
D 1 210 LEU 210 210 210 LEU LEU D . n 
D 1 211 LYS 211 211 211 LYS LYS D . n 
D 1 212 ILE 212 212 212 ILE ILE D . n 
D 1 213 ARG 213 213 213 ARG ARG D . n 
D 1 214 GLN 214 214 214 GLN GLN D . n 
D 1 215 LEU 215 215 215 LEU LEU D . n 
D 1 216 LEU 216 216 216 LEU LEU D . n 
D 1 217 TRP 217 217 217 TRP TRP D . n 
D 1 218 PHE 218 218 218 PHE PHE D . n 
D 1 219 HIS 219 219 219 HIS HIS D . n 
D 1 220 ILE 220 220 220 ILE ILE D . n 
D 1 221 SER 221 221 221 SER SER D . n 
D 1 222 CYS 222 222 222 CYS CYS D . n 
D 1 223 LEU 223 223 223 LEU LEU D . n 
D 1 224 THR 224 224 224 THR THR D . n 
D 1 225 PHE 225 225 225 PHE PHE D . n 
D 1 226 GLY 226 226 226 GLY GLY D . n 
D 1 227 ARG 227 227 227 ARG ARG D . n 
D 1 228 GLU 228 228 228 GLU GLU D . n 
D 1 229 THR 229 229 229 THR THR D . n 
D 1 230 VAL 230 230 230 VAL VAL D . n 
D 1 231 LEU 231 231 231 LEU LEU D . n 
D 1 232 GLU 232 232 232 GLU GLU D . n 
D 1 233 TYR 233 233 233 TYR TYR D . n 
D 1 234 LEU 234 234 234 LEU LEU D . n 
D 1 235 VAL 235 235 235 VAL VAL D . n 
D 1 236 SER 236 236 236 SER SER D . n 
D 1 237 PHE 237 237 237 PHE PHE D . n 
D 1 238 GLY 238 238 238 GLY GLY D . n 
D 1 239 VAL 239 239 239 VAL VAL D . n 
D 1 240 TRP 240 240 240 TRP TRP D . n 
D 1 241 ILE 241 241 241 ILE ILE D . n 
D 1 242 ARG 242 242 242 ARG ARG D . n 
D 1 243 THR 243 243 243 THR THR D . n 
D 1 244 PRO 244 244 244 PRO PRO D . n 
D 1 245 PRO 245 245 245 PRO PRO D . n 
D 1 246 ALA 246 246 246 ALA ALA D . n 
D 1 247 TYR 247 247 247 TYR TYR D . n 
D 1 248 ARG 248 248 248 ARG ARG D . n 
D 1 249 PRO 249 249 249 PRO PRO D . n 
D 1 250 PRO 250 250 250 PRO PRO D . n 
D 1 251 ASN 251 251 251 ASN ASN D . n 
D 1 252 ALA 252 252 252 ALA ALA D . n 
D 1 253 PRO 253 253 253 PRO PRO D . n 
D 1 254 ILE 254 254 254 ILE ILE D . n 
D 1 255 LEU 255 255 255 LEU LEU D . n 
D 1 256 SER 256 256 256 SER SER D . n 
D 1 257 THR 257 257 257 THR THR D . n 
D 1 258 LEU 258 258 258 LEU LEU D . n 
D 1 259 PRO 259 259 ?   ?   ?   D . n 
D 1 260 GLU 260 260 ?   ?   ?   D . n 
D 1 261 THR 261 261 ?   ?   ?   D . n 
D 1 262 THR 262 262 ?   ?   ?   D . n 
D 1 263 VAL 263 263 ?   ?   ?   D . n 
D 1 264 VAL 264 264 ?   ?   ?   D . n 
D 1 265 ARG 265 265 ?   ?   ?   D . n 
D 1 266 ARG 266 266 ?   ?   ?   D . n 
D 1 267 ARG 267 267 ?   ?   ?   D . n 
D 1 268 ASP 268 268 ?   ?   ?   D . n 
D 1 269 ARG 269 269 ?   ?   ?   D . n 
D 1 270 GLY 270 270 ?   ?   ?   D . n 
D 1 271 ARG 271 271 ?   ?   ?   D . n 
D 1 272 SER 272 272 ?   ?   ?   D . n 
D 1 273 PRO 273 273 ?   ?   ?   D . n 
D 1 274 ARG 274 274 ?   ?   ?   D . n 
D 1 275 ARG 275 275 ?   ?   ?   D . n 
D 1 276 ARG 276 276 ?   ?   ?   D . n 
D 1 277 THR 277 277 ?   ?   ?   D . n 
D 1 278 PRO 278 278 ?   ?   ?   D . n 
D 1 279 SER 279 279 ?   ?   ?   D . n 
D 1 280 PRO 280 280 ?   ?   ?   D . n 
D 1 281 ARG 281 281 ?   ?   ?   D . n 
D 1 282 ARG 282 282 ?   ?   ?   D . n 
D 1 283 ARG 283 283 ?   ?   ?   D . n 
D 1 284 ARG 284 284 ?   ?   ?   D . n 
D 1 285 SER 285 285 ?   ?   ?   D . n 
D 1 286 GLN 286 286 ?   ?   ?   D . n 
D 1 287 SER 287 287 ?   ?   ?   D . n 
D 1 288 PRO 288 288 ?   ?   ?   D . n 
D 1 289 ARG 289 289 ?   ?   ?   D . n 
D 1 290 ARG 290 290 ?   ?   ?   D . n 
D 1 291 ARG 291 291 ?   ?   ?   D . n 
D 1 292 ARG 292 292 ?   ?   ?   D . n 
D 1 293 SER 293 293 ?   ?   ?   D . n 
D 1 294 GLN 294 294 ?   ?   ?   D . n 
D 1 295 SER 295 295 ?   ?   ?   D . n 
D 1 296 ARG 296 296 ?   ?   ?   D . n 
D 1 297 GLU 297 297 ?   ?   ?   D . n 
D 1 298 SER 298 298 ?   ?   ?   D . n 
D 1 299 GLN 299 299 ?   ?   ?   D . n 
D 1 300 CYS 300 300 ?   ?   ?   D . n 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FWF 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9FWF 
_struct.title                        'N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus (T=4 VLP)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FWF 
_struct_keywords.text            
'velcrovax, hepatitis b virus, hepatitis b core antigen, affimer, vaccine, recombinant, vlp, antigen display, virus like particle' 
_struct_keywords.pdbx_keywords   'VIRUS LIKE PARTICLE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9FWF 
_struct_ref.pdbx_db_accession          9FWF 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FWF A 1 ? 300 ? 9FWF 1 ? 300 ? 1 300 
2 1 9FWF B 1 ? 300 ? 9FWF 1 ? 300 ? 1 300 
3 1 9FWF C 1 ? 300 ? 9FWF 1 ? 300 ? 1 300 
4 1 9FWF D 1 ? 300 ? 9FWF 1 ? 300 ? 1 300 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   240-meric 
_pdbx_struct_assembly.oligomeric_count     240 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   
;1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60
;
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1  'identity operation'       1_555 x,y,z 1.0       0.0       0.0       0.0        0.0       1.0       0.0       0.0        0.0 
0.0       1.0       0.0        
2  'point symmetry operation' ?     ?     -0.809017 -0.5      0.309017  489.75106  -0.5      0.309017  -0.809017 489.83479  
0.309017  -0.809017 -0.5      489.88655  
3  'point symmetry operation' ?     ?     0.0       1.0       0.0       0.1458     0.0       0.0       -1.0      489.8088   -1.0 
0.0       0.0       489.9546   
4  'point symmetry operation' ?     ?     0.809017  -0.5      -0.309017 244.88534  -0.5      -0.309017 -0.809017 641.11814  
0.309017  0.809017  -0.5      93.8216    
5  'point symmetry operation' ?     ?     0.5       0.309017  -0.809017 245.05319  -0.309017 -0.809017 -0.5      641.0144   
-0.809017 0.5       -0.309017 396.5044   
6  'point symmetry operation' ?     ?     -0.309017 -0.809017 -0.5      641.1602   -0.809017 0.5       -0.309017 396.2588   0.5 
0.309017  -0.809017 245.15299  
7  'point symmetry operation' ?     ?     -0.809017 0.5       -0.309017 396.4046   0.5       0.309017  -0.809017 244.90739  
-0.309017 -0.809017 -0.5      641.26     
8  'point symmetry operation' ?     ?     -0.809017 -0.5      -0.309017 641.1862   0.5       -0.309017 -0.809017 396.19074  
0.309017  -0.809017 0.5       244.85935  
9  'point symmetry operation' ?     ?     -0.309017 0.809017  -0.5      245.09525  -0.809017 -0.5      -0.309017 641.0404   -0.5 
0.309017  0.809017  93.61806   
10 'point symmetry operation' ?     ?     0.5       -0.309017 -0.809017 396.33654  -0.309017 0.809017  -0.5      244.94945  
0.809017  0.5       0.309017  -151.2316  
11 'point symmetry operation' ?     ?     0.0       0.0       -1.0      489.9546   -1.0      0.0       0.0       489.709    0.0 
1.0       0.0       0.2456     
12 'point symmetry operation' ?     ?     -0.5      -0.309017 -0.809017 641.26394  0.309017  0.809017  -0.5      93.576     
0.809017  -0.5      -0.309017 244.98514  
13 'point symmetry operation' ?     ?     -0.5      0.309017  -0.809017 489.98059  0.309017  -0.809017 -0.5      489.64095  
-0.809017 -0.5      0.309017  489.85086  
14 'point symmetry operation' ?     ?     -0.309017 -0.809017 -0.5      641.1602   0.809017  -0.5      0.309017  93.3044    -0.5 
-0.309017 0.809017  244.90141  
15 'point symmetry operation' ?     ?     -0.809017 0.5       -0.309017 396.4046   -0.5      -0.309017 0.809017  244.65581  
0.309017  0.809017  0.5       -151.2056  
16 'point symmetry operation' ?     ?     0.5       0.309017  -0.809017 245.05319  0.309017  0.809017  0.5       -151.4512  
0.809017  -0.5      0.309017  93.55      
17 'point symmetry operation' ?     ?     -0.5      0.309017  -0.809017 489.98059  -0.309017 0.809017  0.5       -0.07775   
0.809017  0.5       -0.309017 0.20354    
18 'point symmetry operation' ?     ?     0.0       0.0       -1.0      489.9546   1.0       0.0       0.0       -0.1458    0.0 
-1.0      0.0       489.8088   
19 'point symmetry operation' ?     ?     -0.5      -0.309017 -0.809017 641.26394  -0.309017 -0.809017 0.5       395.9872   
-0.809017 0.5       0.309017  245.06926  
20 'point symmetry operation' ?     ?     0.0       -1.0      0.0       489.709    0.0       0.0       1.0       -0.2456    -1.0 
0.0       0.0       489.9546   
21 'point symmetry operation' ?     ?     -0.809017 0.5       0.309017  244.96946  0.5       0.309017  0.809017  -151.55494 
0.309017  0.809017  -0.5      93.8216    
22 'point symmetry operation' ?     ?     0.809017  0.5       -0.309017 0.10374    0.5       -0.309017 0.809017  -0.27159   
0.309017  -0.809017 -0.5      489.88655  
23 'point symmetry operation' ?     ?     -0.309017 0.809017  -0.5      245.09525  0.809017  0.5       0.309017  -151.4772  0.5 
-0.309017 -0.809017 396.43634  
24 'point symmetry operation' ?     ?     0.5       -0.309017 -0.809017 396.33654  0.309017  -0.809017 0.5       244.61375  
-0.809017 -0.5      -0.309017 641.286    
25 'point symmetry operation' ?     ?     -0.809017 -0.5      -0.309017 641.1862   -0.5      0.309017  0.809017  93.37246   
-0.309017 0.809017  -0.5      245.19505  
26 'point symmetry operation' ?     ?     -0.309017 -0.809017 0.5       396.133    -0.809017 0.5       0.309017  244.82366  -0.5 
-0.309017 -0.809017 641.36374  
27 'point symmetry operation' ?     ?     -0.309017 0.809017  0.5       0.06805    0.809017  0.5       -0.309017 -0.04206   -0.5 
0.309017  -0.809017 490.08039  
28 'point symmetry operation' ?     ?     1.0       0.0       0.0       0.0        0.0       -1.0      0.0       489.5632   0.0 
0.0       -1.0      490.0544   
29 'point symmetry operation' ?     ?     0.309017  0.809017  -0.5      93.7218    0.809017  -0.5      -0.309017 244.73954  -0.5 
-0.309017 -0.809017 641.36374  
30 'point symmetry operation' ?     ?     0.309017  -0.809017 -0.5      489.78675  -0.809017 -0.5      0.309017  489.60526  -0.5 
0.309017  -0.809017 490.08039  
31 'point symmetry operation' ?     ?     -1.0      0.0       0.0       489.8548   0.0       1.0       0.0       0.0        0.0 
0.0       -1.0      490.0544   
32 'point symmetry operation' ?     ?     0.809017  0.5       -0.309017 0.10374    -0.5      0.309017  -0.809017 489.83479  
-0.309017 0.809017  0.5       0.16785    
33 'point symmetry operation' ?     ?     0.0       -1.0      0.0       489.709    0.0       0.0       -1.0      489.8088   1.0 
0.0       0.0       0.0998     
34 'point symmetry operation' ?     ?     -0.809017 0.5       0.309017  244.96946  -0.5      -0.309017 -0.809017 641.11814  
-0.309017 -0.809017 0.5       396.2328   
35 'point symmetry operation' ?     ?     -0.5      -0.309017 0.809017  244.80161  -0.309017 -0.809017 -0.5      641.0144   
0.809017  -0.5      0.309017  93.55      
36 'point symmetry operation' ?     ?     0.309017  0.809017  0.5       -151.3054  -0.809017 0.5       -0.309017 396.2588   -0.5 
-0.309017 0.809017  244.90141  
37 'point symmetry operation' ?     ?     0.809017  -0.5      0.309017  93.4502    0.5       0.309017  -0.809017 244.90739  
0.309017  0.809017  0.5       -151.2056  
38 'point symmetry operation' ?     ?     0.809017  0.5       0.309017  -151.3314  0.5       -0.309017 -0.809017 396.19074  
-0.309017 0.809017  -0.5      245.19505  
39 'point symmetry operation' ?     ?     0.309017  -0.809017 0.5       244.75955  -0.809017 -0.5      -0.309017 641.0404   0.5 
-0.309017 -0.809017 396.43634  
40 'point symmetry operation' ?     ?     -0.5      0.309017  0.809017  93.51826   -0.309017 0.809017  -0.5      244.94945  
-0.809017 -0.5      -0.309017 641.286    
41 'point symmetry operation' ?     ?     0.0       0.0       1.0       -0.0998    -1.0      0.0       0.0       489.709    0.0 
-1.0      0.0       489.8088   
42 'point symmetry operation' ?     ?     0.5       0.309017  0.809017  -151.40914 0.309017  0.809017  -0.5      93.576     
-0.809017 0.5       0.309017  245.06926  
43 'point symmetry operation' ?     ?     0.5       -0.309017 0.809017  -0.12579   0.309017  -0.809017 -0.5      489.64095  
0.809017  0.5       -0.309017 0.20354    
44 'point symmetry operation' ?     ?     0.309017  0.809017  0.5       -151.3054  0.809017  -0.5      0.309017  93.3044    0.5 
0.309017  -0.809017 245.15299  
45 'point symmetry operation' ?     ?     0.809017  -0.5      0.309017  93.4502    -0.5      -0.309017 0.809017  244.65581  
-0.309017 -0.809017 -0.5      641.26     
46 'point symmetry operation' ?     ?     -0.5      -0.309017 0.809017  244.80161  0.309017  0.809017  0.5       -151.4512  
-0.809017 0.5       -0.309017 396.5044   
47 'point symmetry operation' ?     ?     0.5       -0.309017 0.809017  -0.12579   -0.309017 0.809017  0.5       -0.07775   
-0.809017 -0.5      0.309017  489.85086  
48 'point symmetry operation' ?     ?     0.0       0.0       1.0       -0.0998    1.0       0.0       0.0       -0.1458    0.0 
1.0       0.0       0.2456     
49 'point symmetry operation' ?     ?     0.5       0.309017  0.809017  -151.40914 -0.309017 -0.809017 0.5       395.9872   
0.809017  -0.5      -0.309017 244.98514  
50 'point symmetry operation' ?     ?     0.0       1.0       0.0       0.1458     0.0       0.0       1.0       -0.2456    1.0 
0.0       0.0       0.0998     
51 'point symmetry operation' ?     ?     0.809017  -0.5      -0.309017 244.88534  0.5       0.309017  0.809017  -151.55494 
-0.309017 -0.809017 0.5       396.2328   
52 'point symmetry operation' ?     ?     -0.809017 -0.5      0.309017  489.75106  0.5       -0.309017 0.809017  -0.27159   
-0.309017 0.809017  0.5       0.16785    
53 'point symmetry operation' ?     ?     0.309017  -0.809017 0.5       244.75955  0.809017  0.5       0.309017  -151.4772  -0.5 
0.309017  0.809017  93.61806   
54 'point symmetry operation' ?     ?     -0.5      0.309017  0.809017  93.51826   0.309017  -0.809017 0.5       244.61375  
0.809017  0.5       0.309017  -151.2316  
55 'point symmetry operation' ?     ?     0.809017  0.5       0.309017  -151.3314  -0.5      0.309017  0.809017  93.37246   
0.309017  -0.809017 0.5       244.85935  
56 'point symmetry operation' ?     ?     0.309017  0.809017  -0.5      93.7218    -0.809017 0.5       0.309017  244.82366  0.5 
0.309017  0.809017  -151.30934 
57 'point symmetry operation' ?     ?     0.309017  -0.809017 -0.5      489.78675  0.809017  0.5       -0.309017 -0.04206   0.5 
-0.309017 0.809017  -0.02599   
58 'point symmetry operation' ?     ?     -1.0      0.0       0.0       489.8548   0.0       -1.0      0.0       489.5632   0.0 
0.0       1.0       0.0        
59 'point symmetry operation' ?     ?     -0.309017 -0.809017 0.5       396.133    0.809017  -0.5      -0.309017 244.73954  0.5 
0.309017  0.809017  -151.30934 
60 'point symmetry operation' ?     ?     -0.309017 0.809017  0.5       0.06805    -0.809017 -0.5      0.309017  489.60526  0.5 
-0.309017 0.809017  -0.02599   
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 17  ? GLU A 35  ? SER A 17  GLU A 35  1 ? 19 
HELX_P HELX_P2  AA2 TYR A 116 ? GLY A 120 ? TYR A 116 GLY A 120 5 ? 5  
HELX_P HELX_P3  AA3 GLU A 124 ? PHE A 128 ? GLU A 124 PHE A 128 5 ? 5  
HELX_P HELX_P4  AA4 PRO A 130 ? PHE A 134 ? PRO A 130 PHE A 134 5 ? 5  
HELX_P HELX_P5  AA5 SER A 136 ? TYR A 148 ? SER A 136 TYR A 148 1 ? 13 
HELX_P HELX_P6  AA6 GLU A 150 ? SER A 154 ? GLU A 150 SER A 154 5 ? 5  
HELX_P HELX_P7  AA7 SER A 159 ? GLY A 183 ? SER A 159 GLY A 183 1 ? 25 
HELX_P HELX_P8  AA8 VAL A 200 ? MET A 208 ? VAL A 200 MET A 208 1 ? 9  
HELX_P HELX_P9  AA9 MET A 208 ? GLY A 226 ? MET A 208 GLY A 226 1 ? 19 
HELX_P HELX_P10 AB1 GLY A 226 ? THR A 243 ? GLY A 226 THR A 243 1 ? 18 
HELX_P HELX_P11 AB2 SER B 17  ? GLU B 35  ? SER B 17  GLU B 35  1 ? 19 
HELX_P HELX_P12 AB3 TYR B 116 ? GLY B 120 ? TYR B 116 GLY B 120 5 ? 5  
HELX_P HELX_P13 AB4 THR B 122 ? SER B 127 ? THR B 122 SER B 127 1 ? 6  
HELX_P HELX_P14 AB5 SER B 136 ? GLU B 153 ? SER B 136 GLU B 153 1 ? 18 
HELX_P HELX_P15 AB6 SER B 159 ? ASN B 184 ? SER B 159 ASN B 184 1 ? 26 
HELX_P HELX_P16 AB7 ALA B 195 ? GLY B 226 ? ALA B 195 GLY B 226 1 ? 32 
HELX_P HELX_P17 AB8 ARG B 227 ? THR B 243 ? ARG B 227 THR B 243 1 ? 17 
HELX_P HELX_P18 AB9 PRO B 244 ? ARG B 248 ? PRO B 244 ARG B 248 5 ? 5  
HELX_P HELX_P19 AC1 LEU C 18  ? GLU C 35  ? LEU C 18  GLU C 35  1 ? 18 
HELX_P HELX_P20 AC2 THR C 122 ? SER C 127 ? THR C 122 SER C 127 1 ? 6  
HELX_P HELX_P21 AC3 PRO C 130 ? PHE C 134 ? PRO C 130 PHE C 134 5 ? 5  
HELX_P HELX_P22 AC4 SER C 136 ? ALA C 146 ? SER C 136 ALA C 146 1 ? 11 
HELX_P HELX_P23 AC5 SER C 159 ? ASN C 184 ? SER C 159 ASN C 184 1 ? 26 
HELX_P HELX_P24 AC6 LEU C 199 ? GLY C 226 ? LEU C 199 GLY C 226 1 ? 28 
HELX_P HELX_P25 AC7 GLY C 226 ? THR C 243 ? GLY C 226 THR C 243 1 ? 18 
HELX_P HELX_P26 AC8 PRO C 244 ? ARG C 248 ? PRO C 244 ARG C 248 5 ? 5  
HELX_P HELX_P27 AC9 LEU D 18  ? GLU D 35  ? LEU D 18  GLU D 35  1 ? 18 
HELX_P HELX_P28 AD1 LYS D 117 ? ALA D 121 ? LYS D 117 ALA D 121 5 ? 5  
HELX_P HELX_P29 AD2 PRO D 130 ? PHE D 134 ? PRO D 130 PHE D 134 5 ? 5  
HELX_P HELX_P30 AD3 SER D 136 ? TYR D 148 ? SER D 136 TYR D 148 1 ? 13 
HELX_P HELX_P31 AD4 TYR D 148 ? GLU D 153 ? TYR D 148 GLU D 153 1 ? 6  
HELX_P HELX_P32 AD5 SER D 159 ? ASN D 185 ? SER D 159 ASN D 185 1 ? 27 
HELX_P HELX_P33 AD6 ASP D 198 ? GLY D 226 ? ASP D 198 GLY D 226 1 ? 29 
HELX_P HELX_P34 AD7 GLY D 226 ? THR D 243 ? GLY D 226 THR D 243 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLU A 40 ? GLN A 50  ? GLU A 40 GLN A 50  
AA1 2 MET A 61 ? LYS A 69  ? MET A 61 LYS A 69  
AA2 1 VAL A 81 ? TRP A 82  ? VAL A 81 TRP A 82  
AA2 2 GLU A 97 ? LEU A 98  ? GLU A 97 LEU A 98  
AA3 1 GLU B 40 ? LYS B 48  ? GLU B 40 LYS B 48  
AA3 2 TYR B 63 ? LYS B 69  ? TYR B 63 LYS B 69  
AA3 3 LEU B 76 ? VAL B 81  ? LEU B 76 VAL B 81  
AA3 4 LEU B 98 ? GLU B 100 ? LEU B 98 GLU B 100 
AA4 1 GLU C 40 ? GLN C 50  ? GLU C 40 GLN C 50  
AA4 2 MET C 61 ? ASP C 70  ? MET C 61 ASP C 70  
AA4 3 LYS C 73 ? TRP C 82  ? LYS C 73 TRP C 82  
AA4 4 GLU C 97 ? GLU C 100 ? GLU C 97 GLU C 100 
AA5 1 LEU D 39 ? ARG D 43  ? LEU D 39 ARG D 43  
AA5 2 GLU D 67 ? ASP D 70  ? GLU D 67 ASP D 70  
AA5 3 LYS D 74 ? LEU D 76  ? LYS D 74 LEU D 76  
AA6 1 ALA D 47 ? LYS D 48  ? ALA D 47 LYS D 48  
AA6 2 TYR D 63 ? LEU D 64  ? TYR D 63 LEU D 64  
AA7 1 LYS D 80 ? TRP D 82  ? LYS D 80 TRP D 82  
AA7 2 GLU D 97 ? GLU D 100 ? GLU D 97 GLU D 100 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 40 ? N GLU A 40 O LYS A 69  ? O LYS A 69  
AA2 1 2 N TRP A 82 ? N TRP A 82 O GLU A 97  ? O GLU A 97  
AA3 1 2 N ARG B 43 ? N ARG B 43 O GLU B 67  ? O GLU B 67  
AA3 2 3 N LEU B 64 ? N LEU B 64 O ALA B 79  ? O ALA B 79  
AA3 3 4 N LYS B 80 ? N LYS B 80 O GLU B 100 ? O GLU B 100 
AA4 1 2 N GLU C 40 ? N GLU C 40 O LYS C 69  ? O LYS C 69  
AA4 2 3 N LEU C 64 ? N LEU C 64 O ALA C 79  ? O ALA C 79  
AA4 3 4 N LYS C 80 ? N LYS C 80 O GLN C 99  ? O GLN C 99  
AA5 1 2 N VAL D 42 ? N VAL D 42 O GLU D 67  ? O GLU D 67  
AA5 2 3 N ALA D 68 ? N ALA D 68 O LYS D 75  ? O LYS D 75  
AA6 1 2 N LYS D 48 ? N LYS D 48 O TYR D 63  ? O TYR D 63  
AA7 1 2 N LYS D 80 ? N LYS D 80 O GLN D 99  ? O GLN D 99  
# 
_pdbx_entry_details.entry_id                   9FWF 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 36  ? ? 62.83   60.75   
2  1 ALA A 107 ? ? -92.00  52.05   
3  1 PRO A 130 ? ? -69.73  -176.96 
4  1 THR A 206 ? ? -94.60  -65.06  
5  1 ASN B 36  ? ? 60.98   65.16   
6  1 VAL B 42  ? ? -123.74 -59.12  
7  1 PHE B 101 ? ? -145.74 15.05   
8  1 TYR B 148 ? ? -141.76 27.81   
9  1 CYS B 158 ? ? 72.93   -17.71  
10 1 THR B 206 ? ? -92.59  -60.67  
11 1 TYR D 93  ? ? -95.64  57.27   
12 1 PHE D 119 ? ? 66.66   -5.77   
13 1 ASP D 132 ? ? -93.08  45.97   
14 1 PRO D 155 ? ? -85.54  45.61   
15 1 SER D 196 ? ? -99.27  38.55   
16 1 ARG D 197 ? ? -88.77  30.56   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FWF 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9FWF 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               56416 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'T=4 virus-like particle for N-VelcroVax HBcAg' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9FWF 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2900 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9FWF 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FWF 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9FWF 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        I 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ALA 2   ? A ALA 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A ALA 5   ? A ALA 5   
6   1 Y 1 A THR 6   ? A THR 6   
7   1 Y 1 A GLY 7   ? A GLY 7   
8   1 Y 1 A VAL 8   ? A VAL 8   
9   1 Y 1 A ARG 9   ? A ARG 9   
10  1 Y 1 A ALA 10  ? A ALA 10  
11  1 Y 1 A VAL 11  ? A VAL 11  
12  1 Y 1 A PRO 12  ? A PRO 12  
13  1 Y 1 A GLY 13  ? A GLY 13  
14  1 Y 1 A ILE 53  ? A ILE 53  
15  1 Y 1 A HIS 54  ? A HIS 54  
16  1 Y 1 A GLU 55  ? A GLU 55  
17  1 Y 1 A ASN 56  ? A ASN 56  
18  1 Y 1 A ASP 57  ? A ASP 57  
19  1 Y 1 A ALA 58  ? A ALA 58  
20  1 Y 1 A LYS 84  ? A LYS 84  
21  1 Y 1 A GLY 85  ? A GLY 85  
22  1 Y 1 A ILE 86  ? A ILE 86  
23  1 Y 1 A MET 87  ? A MET 87  
24  1 Y 1 A ASP 88  ? A ASP 88  
25  1 Y 1 A GLU 187 ? A GLU 187 
26  1 Y 1 A PHE 188 ? A PHE 188 
27  1 Y 1 A ALA 189 ? A ALA 189 
28  1 Y 1 A GLY 190 ? A GLY 190 
29  1 Y 1 A ALA 191 ? A ALA 191 
30  1 Y 1 A SER 192 ? A SER 192 
31  1 Y 1 A ASP 193 ? A ASP 193 
32  1 Y 1 A PRO 194 ? A PRO 194 
33  1 Y 1 A ALA 195 ? A ALA 195 
34  1 Y 1 A SER 196 ? A SER 196 
35  1 Y 1 A ARG 197 ? A ARG 197 
36  1 Y 1 A PRO 259 ? A PRO 259 
37  1 Y 1 A GLU 260 ? A GLU 260 
38  1 Y 1 A THR 261 ? A THR 261 
39  1 Y 1 A THR 262 ? A THR 262 
40  1 Y 1 A VAL 263 ? A VAL 263 
41  1 Y 1 A VAL 264 ? A VAL 264 
42  1 Y 1 A ARG 265 ? A ARG 265 
43  1 Y 1 A ARG 266 ? A ARG 266 
44  1 Y 1 A ARG 267 ? A ARG 267 
45  1 Y 1 A ASP 268 ? A ASP 268 
46  1 Y 1 A ARG 269 ? A ARG 269 
47  1 Y 1 A GLY 270 ? A GLY 270 
48  1 Y 1 A ARG 271 ? A ARG 271 
49  1 Y 1 A SER 272 ? A SER 272 
50  1 Y 1 A PRO 273 ? A PRO 273 
51  1 Y 1 A ARG 274 ? A ARG 274 
52  1 Y 1 A ARG 275 ? A ARG 275 
53  1 Y 1 A ARG 276 ? A ARG 276 
54  1 Y 1 A THR 277 ? A THR 277 
55  1 Y 1 A PRO 278 ? A PRO 278 
56  1 Y 1 A SER 279 ? A SER 279 
57  1 Y 1 A PRO 280 ? A PRO 280 
58  1 Y 1 A ARG 281 ? A ARG 281 
59  1 Y 1 A ARG 282 ? A ARG 282 
60  1 Y 1 A ARG 283 ? A ARG 283 
61  1 Y 1 A ARG 284 ? A ARG 284 
62  1 Y 1 A SER 285 ? A SER 285 
63  1 Y 1 A GLN 286 ? A GLN 286 
64  1 Y 1 A SER 287 ? A SER 287 
65  1 Y 1 A PRO 288 ? A PRO 288 
66  1 Y 1 A ARG 289 ? A ARG 289 
67  1 Y 1 A ARG 290 ? A ARG 290 
68  1 Y 1 A ARG 291 ? A ARG 291 
69  1 Y 1 A ARG 292 ? A ARG 292 
70  1 Y 1 A SER 293 ? A SER 293 
71  1 Y 1 A GLN 294 ? A GLN 294 
72  1 Y 1 A SER 295 ? A SER 295 
73  1 Y 1 A ARG 296 ? A ARG 296 
74  1 Y 1 A GLU 297 ? A GLU 297 
75  1 Y 1 A SER 298 ? A SER 298 
76  1 Y 1 A GLN 299 ? A GLN 299 
77  1 Y 1 A CYS 300 ? A CYS 300 
78  1 Y 1 B MET 1   ? B MET 1   
79  1 Y 1 B ALA 2   ? B ALA 2   
80  1 Y 1 B SER 3   ? B SER 3   
81  1 Y 1 B ALA 4   ? B ALA 4   
82  1 Y 1 B ALA 5   ? B ALA 5   
83  1 Y 1 B THR 6   ? B THR 6   
84  1 Y 1 B GLY 7   ? B GLY 7   
85  1 Y 1 B VAL 8   ? B VAL 8   
86  1 Y 1 B ARG 9   ? B ARG 9   
87  1 Y 1 B ALA 10  ? B ALA 10  
88  1 Y 1 B VAL 11  ? B VAL 11  
89  1 Y 1 B PRO 12  ? B PRO 12  
90  1 Y 1 B GLY 13  ? B GLY 13  
91  1 Y 1 B ILE 53  ? B ILE 53  
92  1 Y 1 B HIS 54  ? B HIS 54  
93  1 Y 1 B GLU 55  ? B GLU 55  
94  1 Y 1 B ASN 56  ? B ASN 56  
95  1 Y 1 B ASP 57  ? B ASP 57  
96  1 Y 1 B ALA 58  ? B ALA 58  
97  1 Y 1 B LYS 84  ? B LYS 84  
98  1 Y 1 B GLY 85  ? B GLY 85  
99  1 Y 1 B ILE 86  ? B ILE 86  
100 1 Y 1 B MET 87  ? B MET 87  
101 1 Y 1 B ASP 88  ? B ASP 88  
102 1 Y 1 B ASN 185 ? B ASN 185 
103 1 Y 1 B LEU 186 ? B LEU 186 
104 1 Y 1 B GLU 187 ? B GLU 187 
105 1 Y 1 B PHE 188 ? B PHE 188 
106 1 Y 1 B ALA 189 ? B ALA 189 
107 1 Y 1 B GLY 190 ? B GLY 190 
108 1 Y 1 B ALA 191 ? B ALA 191 
109 1 Y 1 B SER 192 ? B SER 192 
110 1 Y 1 B ASP 193 ? B ASP 193 
111 1 Y 1 B PRO 259 ? B PRO 259 
112 1 Y 1 B GLU 260 ? B GLU 260 
113 1 Y 1 B THR 261 ? B THR 261 
114 1 Y 1 B THR 262 ? B THR 262 
115 1 Y 1 B VAL 263 ? B VAL 263 
116 1 Y 1 B VAL 264 ? B VAL 264 
117 1 Y 1 B ARG 265 ? B ARG 265 
118 1 Y 1 B ARG 266 ? B ARG 266 
119 1 Y 1 B ARG 267 ? B ARG 267 
120 1 Y 1 B ASP 268 ? B ASP 268 
121 1 Y 1 B ARG 269 ? B ARG 269 
122 1 Y 1 B GLY 270 ? B GLY 270 
123 1 Y 1 B ARG 271 ? B ARG 271 
124 1 Y 1 B SER 272 ? B SER 272 
125 1 Y 1 B PRO 273 ? B PRO 273 
126 1 Y 1 B ARG 274 ? B ARG 274 
127 1 Y 1 B ARG 275 ? B ARG 275 
128 1 Y 1 B ARG 276 ? B ARG 276 
129 1 Y 1 B THR 277 ? B THR 277 
130 1 Y 1 B PRO 278 ? B PRO 278 
131 1 Y 1 B SER 279 ? B SER 279 
132 1 Y 1 B PRO 280 ? B PRO 280 
133 1 Y 1 B ARG 281 ? B ARG 281 
134 1 Y 1 B ARG 282 ? B ARG 282 
135 1 Y 1 B ARG 283 ? B ARG 283 
136 1 Y 1 B ARG 284 ? B ARG 284 
137 1 Y 1 B SER 285 ? B SER 285 
138 1 Y 1 B GLN 286 ? B GLN 286 
139 1 Y 1 B SER 287 ? B SER 287 
140 1 Y 1 B PRO 288 ? B PRO 288 
141 1 Y 1 B ARG 289 ? B ARG 289 
142 1 Y 1 B ARG 290 ? B ARG 290 
143 1 Y 1 B ARG 291 ? B ARG 291 
144 1 Y 1 B ARG 292 ? B ARG 292 
145 1 Y 1 B SER 293 ? B SER 293 
146 1 Y 1 B GLN 294 ? B GLN 294 
147 1 Y 1 B SER 295 ? B SER 295 
148 1 Y 1 B ARG 296 ? B ARG 296 
149 1 Y 1 B GLU 297 ? B GLU 297 
150 1 Y 1 B SER 298 ? B SER 298 
151 1 Y 1 B GLN 299 ? B GLN 299 
152 1 Y 1 B CYS 300 ? B CYS 300 
153 1 Y 1 C MET 1   ? C MET 1   
154 1 Y 1 C ALA 2   ? C ALA 2   
155 1 Y 1 C SER 3   ? C SER 3   
156 1 Y 1 C ALA 4   ? C ALA 4   
157 1 Y 1 C ALA 5   ? C ALA 5   
158 1 Y 1 C THR 6   ? C THR 6   
159 1 Y 1 C GLY 7   ? C GLY 7   
160 1 Y 1 C VAL 8   ? C VAL 8   
161 1 Y 1 C ARG 9   ? C ARG 9   
162 1 Y 1 C ALA 10  ? C ALA 10  
163 1 Y 1 C VAL 11  ? C VAL 11  
164 1 Y 1 C PRO 12  ? C PRO 12  
165 1 Y 1 C GLY 13  ? C GLY 13  
166 1 Y 1 C ILE 53  ? C ILE 53  
167 1 Y 1 C HIS 54  ? C HIS 54  
168 1 Y 1 C GLU 55  ? C GLU 55  
169 1 Y 1 C ASN 56  ? C ASN 56  
170 1 Y 1 C ASP 57  ? C ASP 57  
171 1 Y 1 C ALA 58  ? C ALA 58  
172 1 Y 1 C LYS 84  ? C LYS 84  
173 1 Y 1 C GLY 85  ? C GLY 85  
174 1 Y 1 C ILE 86  ? C ILE 86  
175 1 Y 1 C MET 87  ? C MET 87  
176 1 Y 1 C ASP 88  ? C ASP 88  
177 1 Y 1 C GLU 187 ? C GLU 187 
178 1 Y 1 C PHE 188 ? C PHE 188 
179 1 Y 1 C ALA 189 ? C ALA 189 
180 1 Y 1 C GLY 190 ? C GLY 190 
181 1 Y 1 C ALA 191 ? C ALA 191 
182 1 Y 1 C SER 192 ? C SER 192 
183 1 Y 1 C ASP 193 ? C ASP 193 
184 1 Y 1 C PRO 194 ? C PRO 194 
185 1 Y 1 C ALA 195 ? C ALA 195 
186 1 Y 1 C SER 196 ? C SER 196 
187 1 Y 1 C ARG 197 ? C ARG 197 
188 1 Y 1 C LEU 258 ? C LEU 258 
189 1 Y 1 C PRO 259 ? C PRO 259 
190 1 Y 1 C GLU 260 ? C GLU 260 
191 1 Y 1 C THR 261 ? C THR 261 
192 1 Y 1 C THR 262 ? C THR 262 
193 1 Y 1 C VAL 263 ? C VAL 263 
194 1 Y 1 C VAL 264 ? C VAL 264 
195 1 Y 1 C ARG 265 ? C ARG 265 
196 1 Y 1 C ARG 266 ? C ARG 266 
197 1 Y 1 C ARG 267 ? C ARG 267 
198 1 Y 1 C ASP 268 ? C ASP 268 
199 1 Y 1 C ARG 269 ? C ARG 269 
200 1 Y 1 C GLY 270 ? C GLY 270 
201 1 Y 1 C ARG 271 ? C ARG 271 
202 1 Y 1 C SER 272 ? C SER 272 
203 1 Y 1 C PRO 273 ? C PRO 273 
204 1 Y 1 C ARG 274 ? C ARG 274 
205 1 Y 1 C ARG 275 ? C ARG 275 
206 1 Y 1 C ARG 276 ? C ARG 276 
207 1 Y 1 C THR 277 ? C THR 277 
208 1 Y 1 C PRO 278 ? C PRO 278 
209 1 Y 1 C SER 279 ? C SER 279 
210 1 Y 1 C PRO 280 ? C PRO 280 
211 1 Y 1 C ARG 281 ? C ARG 281 
212 1 Y 1 C ARG 282 ? C ARG 282 
213 1 Y 1 C ARG 283 ? C ARG 283 
214 1 Y 1 C ARG 284 ? C ARG 284 
215 1 Y 1 C SER 285 ? C SER 285 
216 1 Y 1 C GLN 286 ? C GLN 286 
217 1 Y 1 C SER 287 ? C SER 287 
218 1 Y 1 C PRO 288 ? C PRO 288 
219 1 Y 1 C ARG 289 ? C ARG 289 
220 1 Y 1 C ARG 290 ? C ARG 290 
221 1 Y 1 C ARG 291 ? C ARG 291 
222 1 Y 1 C ARG 292 ? C ARG 292 
223 1 Y 1 C SER 293 ? C SER 293 
224 1 Y 1 C GLN 294 ? C GLN 294 
225 1 Y 1 C SER 295 ? C SER 295 
226 1 Y 1 C ARG 296 ? C ARG 296 
227 1 Y 1 C GLU 297 ? C GLU 297 
228 1 Y 1 C SER 298 ? C SER 298 
229 1 Y 1 C GLN 299 ? C GLN 299 
230 1 Y 1 C CYS 300 ? C CYS 300 
231 1 Y 1 D MET 1   ? D MET 1   
232 1 Y 1 D ALA 2   ? D ALA 2   
233 1 Y 1 D SER 3   ? D SER 3   
234 1 Y 1 D ALA 4   ? D ALA 4   
235 1 Y 1 D ALA 5   ? D ALA 5   
236 1 Y 1 D THR 6   ? D THR 6   
237 1 Y 1 D GLY 7   ? D GLY 7   
238 1 Y 1 D VAL 8   ? D VAL 8   
239 1 Y 1 D ARG 9   ? D ARG 9   
240 1 Y 1 D ALA 10  ? D ALA 10  
241 1 Y 1 D VAL 11  ? D VAL 11  
242 1 Y 1 D PRO 12  ? D PRO 12  
243 1 Y 1 D GLY 13  ? D GLY 13  
244 1 Y 1 D ILE 53  ? D ILE 53  
245 1 Y 1 D HIS 54  ? D HIS 54  
246 1 Y 1 D GLU 55  ? D GLU 55  
247 1 Y 1 D ASN 56  ? D ASN 56  
248 1 Y 1 D ASP 57  ? D ASP 57  
249 1 Y 1 D ALA 58  ? D ALA 58  
250 1 Y 1 D LYS 84  ? D LYS 84  
251 1 Y 1 D GLY 85  ? D GLY 85  
252 1 Y 1 D ILE 86  ? D ILE 86  
253 1 Y 1 D MET 87  ? D MET 87  
254 1 Y 1 D ASP 88  ? D ASP 88  
255 1 Y 1 D LEU 186 ? D LEU 186 
256 1 Y 1 D GLU 187 ? D GLU 187 
257 1 Y 1 D PHE 188 ? D PHE 188 
258 1 Y 1 D ALA 189 ? D ALA 189 
259 1 Y 1 D GLY 190 ? D GLY 190 
260 1 Y 1 D ALA 191 ? D ALA 191 
261 1 Y 1 D SER 192 ? D SER 192 
262 1 Y 1 D ASP 193 ? D ASP 193 
263 1 Y 1 D PRO 259 ? D PRO 259 
264 1 Y 1 D GLU 260 ? D GLU 260 
265 1 Y 1 D THR 261 ? D THR 261 
266 1 Y 1 D THR 262 ? D THR 262 
267 1 Y 1 D VAL 263 ? D VAL 263 
268 1 Y 1 D VAL 264 ? D VAL 264 
269 1 Y 1 D ARG 265 ? D ARG 265 
270 1 Y 1 D ARG 266 ? D ARG 266 
271 1 Y 1 D ARG 267 ? D ARG 267 
272 1 Y 1 D ASP 268 ? D ASP 268 
273 1 Y 1 D ARG 269 ? D ARG 269 
274 1 Y 1 D GLY 270 ? D GLY 270 
275 1 Y 1 D ARG 271 ? D ARG 271 
276 1 Y 1 D SER 272 ? D SER 272 
277 1 Y 1 D PRO 273 ? D PRO 273 
278 1 Y 1 D ARG 274 ? D ARG 274 
279 1 Y 1 D ARG 275 ? D ARG 275 
280 1 Y 1 D ARG 276 ? D ARG 276 
281 1 Y 1 D THR 277 ? D THR 277 
282 1 Y 1 D PRO 278 ? D PRO 278 
283 1 Y 1 D SER 279 ? D SER 279 
284 1 Y 1 D PRO 280 ? D PRO 280 
285 1 Y 1 D ARG 281 ? D ARG 281 
286 1 Y 1 D ARG 282 ? D ARG 282 
287 1 Y 1 D ARG 283 ? D ARG 283 
288 1 Y 1 D ARG 284 ? D ARG 284 
289 1 Y 1 D SER 285 ? D SER 285 
290 1 Y 1 D GLN 286 ? D GLN 286 
291 1 Y 1 D SER 287 ? D SER 287 
292 1 Y 1 D PRO 288 ? D PRO 288 
293 1 Y 1 D ARG 289 ? D ARG 289 
294 1 Y 1 D ARG 290 ? D ARG 290 
295 1 Y 1 D ARG 291 ? D ARG 291 
296 1 Y 1 D ARG 292 ? D ARG 292 
297 1 Y 1 D SER 293 ? D SER 293 
298 1 Y 1 D GLN 294 ? D GLN 294 
299 1 Y 1 D SER 295 ? D SER 295 
300 1 Y 1 D ARG 296 ? D ARG 296 
301 1 Y 1 D GLU 297 ? D GLU 297 
302 1 Y 1 D SER 298 ? D SER 298 
303 1 Y 1 D GLN 299 ? D GLN 299 
304 1 Y 1 D CYS 300 ? D CYS 300 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-30 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FWF 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus (T=4 VLP)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          32630 
_em_entity_assembly_naturalsource.organism             'synthetic construct' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         43 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.14_3260: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?          
MASKING                    ? 4  ? ? ? ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?          
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?          
'MODEL FITTING'            ? 8  ? ? ? ?      ?          
OTHER                      ? 9  ? ? ? ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Wellcome Trust' 'United Kingdom' 102174/B/13/Z 1 
'Wellcome Trust' 'United Kingdom' 108466/Z/15/Z 2 
# 
_atom_sites.entry_id                    9FWF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASN A 1 14  ? 313.072 306.777 93.267  1.00 87.08  ? 14  ASN A N   1 
ATOM 2    C CA  . ASN A 1 14  ? 312.196 307.855 92.824  1.00 87.08  ? 14  ASN A CA  1 
ATOM 3    C C   . ASN A 1 14  ? 310.738 307.597 93.198  1.00 87.08  ? 14  ASN A C   1 
ATOM 4    O O   . ASN A 1 14  ? 310.439 306.696 93.983  1.00 87.08  ? 14  ASN A O   1 
ATOM 5    C CB  . ASN A 1 14  ? 312.343 308.069 91.313  1.00 87.08  ? 14  ASN A CB  1 
ATOM 6    C CG  . ASN A 1 14  ? 312.300 306.769 90.522  1.00 87.08  ? 14  ASN A CG  1 
ATOM 7    O OD1 . ASN A 1 14  ? 311.416 305.933 90.707  1.00 87.08  ? 14  ASN A OD1 1 
ATOM 8    N ND2 . ASN A 1 14  ? 313.268 306.598 89.628  1.00 87.08  ? 14  ASN A ND2 1 
ATOM 9    N N   . GLU A 1 15  ? 309.833 308.395 92.634  1.00 93.28  ? 15  GLU A N   1 
ATOM 10   C CA  . GLU A 1 15  ? 308.418 308.322 92.976  1.00 93.28  ? 15  GLU A CA  1 
ATOM 11   C C   . GLU A 1 15  ? 307.518 308.154 91.762  1.00 93.28  ? 15  GLU A C   1 
ATOM 12   O O   . GLU A 1 15  ? 306.522 307.424 91.834  1.00 93.28  ? 15  GLU A O   1 
ATOM 13   C CB  . GLU A 1 15  ? 308.007 309.580 93.758  1.00 93.28  ? 15  GLU A CB  1 
ATOM 14   C CG  . GLU A 1 15  ? 306.752 309.414 94.602  1.00 93.28  ? 15  GLU A CG  1 
ATOM 15   C CD  . GLU A 1 15  ? 306.730 310.344 95.799  1.00 93.28  ? 15  GLU A CD  1 
ATOM 16   O OE1 . GLU A 1 15  ? 306.729 311.577 95.597  1.00 93.28  ? 15  GLU A OE1 1 
ATOM 17   O OE2 . GLU A 1 15  ? 306.718 309.843 96.942  1.00 93.28  ? 15  GLU A OE2 1 
ATOM 18   N N   . ASN A 1 16  ? 307.834 308.809 90.646  1.00 93.30  ? 16  ASN A N   1 
ATOM 19   C CA  . ASN A 1 16  ? 306.934 308.875 89.503  1.00 93.30  ? 16  ASN A CA  1 
ATOM 20   C C   . ASN A 1 16  ? 307.472 308.167 88.266  1.00 93.30  ? 16  ASN A C   1 
ATOM 21   O O   . ASN A 1 16  ? 306.927 308.359 87.174  1.00 93.30  ? 16  ASN A O   1 
ATOM 22   C CB  . ASN A 1 16  ? 306.625 310.334 89.166  1.00 93.30  ? 16  ASN A CB  1 
ATOM 23   C CG  . ASN A 1 16  ? 305.336 310.816 89.794  1.00 93.30  ? 16  ASN A CG  1 
ATOM 24   O OD1 . ASN A 1 16  ? 304.256 310.312 89.487  1.00 93.30  ? 16  ASN A OD1 1 
ATOM 25   N ND2 . ASN A 1 16  ? 305.442 311.798 90.680  1.00 93.30  ? 16  ASN A ND2 1 
ATOM 26   N N   . SER A 1 17  ? 308.518 307.358 88.402  1.00 83.20  ? 17  SER A N   1 
ATOM 27   C CA  . SER A 1 17  ? 309.094 306.697 87.242  1.00 83.20  ? 17  SER A CA  1 
ATOM 28   C C   . SER A 1 17  ? 308.362 305.388 86.945  1.00 83.20  ? 17  SER A C   1 
ATOM 29   O O   . SER A 1 17  ? 307.331 305.063 87.541  1.00 83.20  ? 17  SER A O   1 
ATOM 30   C CB  . SER A 1 17  ? 310.585 306.458 87.453  1.00 83.20  ? 17  SER A CB  1 
ATOM 31   O OG  . SER A 1 17  ? 310.804 305.238 88.131  1.00 83.20  ? 17  SER A OG  1 
ATOM 32   N N   . LEU A 1 18  ? 308.918 304.622 86.004  1.00 75.88  ? 18  LEU A N   1 
ATOM 33   C CA  . LEU A 1 18  ? 308.251 303.437 85.480  1.00 75.88  ? 18  LEU A CA  1 
ATOM 34   C C   . LEU A 1 18  ? 308.443 302.213 86.368  1.00 75.88  ? 18  LEU A C   1 
ATOM 35   O O   . LEU A 1 18  ? 307.607 301.301 86.326  1.00 75.88  ? 18  LEU A O   1 
ATOM 36   C CB  . LEU A 1 18  ? 308.766 303.164 84.059  1.00 75.88  ? 18  LEU A CB  1 
ATOM 37   C CG  . LEU A 1 18  ? 307.953 302.493 82.940  1.00 75.88  ? 18  LEU A CG  1 
ATOM 38   C CD1 . LEU A 1 18  ? 308.656 302.747 81.620  1.00 75.88  ? 18  LEU A CD1 1 
ATOM 39   C CD2 . LEU A 1 18  ? 307.762 300.995 83.112  1.00 75.88  ? 18  LEU A CD2 1 
ATOM 40   N N   . GLU A 1 19  ? 309.502 302.186 87.186  1.00 77.98  ? 19  GLU A N   1 
ATOM 41   C CA  . GLU A 1 19  ? 309.824 300.975 87.938  1.00 77.98  ? 19  GLU A CA  1 
ATOM 42   C C   . GLU A 1 19  ? 308.808 300.715 89.044  1.00 77.98  ? 19  GLU A C   1 
ATOM 43   O O   . GLU A 1 19  ? 308.393 299.569 89.249  1.00 77.98  ? 19  GLU A O   1 
ATOM 44   C CB  . GLU A 1 19  ? 311.251 301.053 88.496  1.00 77.98  ? 19  GLU A CB  1 
ATOM 45   C CG  . GLU A 1 19  ? 311.602 302.298 89.300  1.00 77.98  ? 19  GLU A CG  1 
ATOM 46   C CD  . GLU A 1 19  ? 311.329 302.142 90.784  1.00 77.98  ? 19  GLU A CD  1 
ATOM 47   O OE1 . GLU A 1 19  ? 310.976 303.148 91.430  1.00 77.98  ? 19  GLU A OE1 1 
ATOM 48   O OE2 . GLU A 1 19  ? 311.478 301.017 91.307  1.00 77.98  ? 19  GLU A OE2 1 
ATOM 49   N N   . ILE A 1 20  ? 308.343 301.765 89.724  1.00 73.04  ? 20  ILE A N   1 
ATOM 50   C CA  . ILE A 1 20  ? 307.322 301.560 90.742  1.00 73.04  ? 20  ILE A CA  1 
ATOM 51   C C   . ILE A 1 20  ? 305.953 301.323 90.115  1.00 73.04  ? 20  ILE A C   1 
ATOM 52   O O   . ILE A 1 20  ? 305.104 300.677 90.736  1.00 73.04  ? 20  ILE A O   1 
ATOM 53   C CB  . ILE A 1 20  ? 307.313 302.727 91.749  1.00 73.04  ? 20  ILE A CB  1 
ATOM 54   C CG1 . ILE A 1 20  ? 306.807 302.245 93.111  1.00 73.04  ? 20  ILE A CG1 1 
ATOM 55   C CG2 . ILE A 1 20  ? 306.509 303.925 91.242  1.00 73.04  ? 20  ILE A CG2 1 
ATOM 56   C CD1 . ILE A 1 20  ? 307.699 301.204 93.751  1.00 73.04  ? 20  ILE A CD1 1 
ATOM 57   N N   . GLU A 1 21  ? 305.741 301.753 88.866  1.00 74.47  ? 21  GLU A N   1 
ATOM 58   C CA  . GLU A 1 21  ? 304.488 301.447 88.185  1.00 74.47  ? 21  GLU A CA  1 
ATOM 59   C C   . GLU A 1 21  ? 304.438 299.976 87.789  1.00 74.47  ? 21  GLU A C   1 
ATOM 60   O O   . GLU A 1 21  ? 303.410 299.313 87.976  1.00 74.47  ? 21  GLU A O   1 
ATOM 61   C CB  . GLU A 1 21  ? 304.325 302.367 86.969  1.00 74.47  ? 21  GLU A CB  1 
ATOM 62   C CG  . GLU A 1 21  ? 302.903 302.500 86.396  1.00 74.47  ? 21  GLU A CG  1 
ATOM 63   C CD  . GLU A 1 21  ? 302.442 301.319 85.553  1.00 74.47  ? 21  GLU A CD  1 
ATOM 64   O OE1 . GLU A 1 21  ? 303.302 300.601 84.997  1.00 74.47  ? 21  GLU A OE1 1 
ATOM 65   O OE2 . GLU A 1 21  ? 301.215 301.115 85.445  1.00 74.47  ? 21  GLU A OE2 1 
ATOM 66   N N   . GLU A 1 22  ? 305.544 299.451 87.250  1.00 73.70  ? 22  GLU A N   1 
ATOM 67   C CA  . GLU A 1 22  ? 305.623 298.025 86.943  1.00 73.70  ? 22  GLU A CA  1 
ATOM 68   C C   . GLU A 1 22  ? 305.576 297.196 88.220  1.00 73.70  ? 22  GLU A C   1 
ATOM 69   O O   . GLU A 1 22  ? 304.974 296.117 88.248  1.00 73.70  ? 22  GLU A O   1 
ATOM 70   C CB  . GLU A 1 22  ? 306.891 297.743 86.124  1.00 73.70  ? 22  GLU A CB  1 
ATOM 71   C CG  . GLU A 1 22  ? 307.238 296.267 85.835  1.00 73.70  ? 22  GLU A CG  1 
ATOM 72   C CD  . GLU A 1 22  ? 308.070 295.599 86.924  1.00 73.70  ? 22  GLU A CD  1 
ATOM 73   O OE1 . GLU A 1 22  ? 308.572 296.322 87.812  1.00 73.70  ? 22  GLU A OE1 1 
ATOM 74   O OE2 . GLU A 1 22  ? 308.211 294.360 86.896  1.00 73.70  ? 22  GLU A OE2 1 
ATOM 75   N N   . LEU A 1 23  ? 306.176 297.711 89.297  1.00 72.99  ? 23  LEU A N   1 
ATOM 76   C CA  . LEU A 1 23  ? 306.166 297.028 90.584  1.00 72.99  ? 23  LEU A CA  1 
ATOM 77   C C   . LEU A 1 23  ? 304.759 296.975 91.172  1.00 72.99  ? 23  LEU A C   1 
ATOM 78   O O   . LEU A 1 23  ? 304.340 295.939 91.701  1.00 72.99  ? 23  LEU A O   1 
ATOM 79   C CB  . LEU A 1 23  ? 307.152 297.745 91.509  1.00 72.99  ? 23  LEU A CB  1 
ATOM 80   C CG  . LEU A 1 23  ? 307.816 297.113 92.727  1.00 72.99  ? 23  LEU A CG  1 
ATOM 81   C CD1 . LEU A 1 23  ? 309.149 297.785 92.955  1.00 72.99  ? 23  LEU A CD1 1 
ATOM 82   C CD2 . LEU A 1 23  ? 306.957 297.343 93.933  1.00 72.99  ? 23  LEU A CD2 1 
ATOM 83   N N   . ALA A 1 24  ? 303.993 298.060 91.031  1.00 73.93  ? 24  ALA A N   1 
ATOM 84   C CA  . ALA A 1 24  ? 302.621 298.086 91.522  1.00 73.93  ? 24  ALA A CA  1 
ATOM 85   C C   . ALA A 1 24  ? 301.682 297.253 90.663  1.00 73.93  ? 24  ALA A C   1 
ATOM 86   O O   . ALA A 1 24  ? 300.755 296.631 91.196  1.00 73.93  ? 24  ALA A O   1 
ATOM 87   C CB  . ALA A 1 24  ? 302.122 299.527 91.596  1.00 73.93  ? 24  ALA A CB  1 
ATOM 88   N N   . ARG A 1 25  ? 301.906 297.213 89.347  1.00 75.70  ? 25  ARG A N   1 
ATOM 89   C CA  . ARG A 1 25  ? 301.106 296.336 88.500  1.00 75.70  ? 25  ARG A CA  1 
ATOM 90   C C   . ARG A 1 25  ? 301.421 294.870 88.774  1.00 75.70  ? 25  ARG A C   1 
ATOM 91   O O   . ARG A 1 25  ? 300.517 294.026 88.764  1.00 75.70  ? 25  ARG A O   1 
ATOM 92   C CB  . ARG A 1 25  ? 301.334 296.676 87.031  1.00 75.70  ? 25  ARG A CB  1 
ATOM 93   C CG  . ARG A 1 25  ? 300.691 297.983 86.609  1.00 75.70  ? 25  ARG A CG  1 
ATOM 94   C CD  . ARG A 1 25  ? 300.253 297.934 85.159  1.00 75.70  ? 25  ARG A CD  1 
ATOM 95   N NE  . ARG A 1 25  ? 299.503 299.125 84.778  1.00 75.70  ? 25  ARG A NE  1 
ATOM 96   C CZ  . ARG A 1 25  ? 298.194 299.272 84.949  1.00 75.70  ? 25  ARG A CZ  1 
ATOM 97   N NH1 . ARG A 1 25  ? 297.478 298.299 85.497  1.00 75.70  ? 25  ARG A NH1 1 
ATOM 98   N NH2 . ARG A 1 25  ? 297.599 300.394 84.569  1.00 75.70  ? 25  ARG A NH2 1 
ATOM 99   N N   . PHE A 1 26  ? 302.691 294.557 89.054  1.00 78.34  ? 26  PHE A N   1 
ATOM 100  C CA  . PHE A 1 26  ? 303.055 293.204 89.459  1.00 78.34  ? 26  PHE A CA  1 
ATOM 101  C C   . PHE A 1 26  ? 302.434 292.846 90.801  1.00 78.34  ? 26  PHE A C   1 
ATOM 102  O O   . PHE A 1 26  ? 301.988 291.711 91.003  1.00 78.34  ? 26  PHE A O   1 
ATOM 103  C CB  . PHE A 1 26  ? 304.575 293.063 89.520  1.00 78.34  ? 26  PHE A CB  1 
ATOM 104  C CG  . PHE A 1 26  ? 305.036 291.681 89.871  1.00 78.34  ? 26  PHE A CG  1 
ATOM 105  C CD1 . PHE A 1 26  ? 304.528 290.578 89.201  1.00 78.34  ? 26  PHE A CD1 1 
ATOM 106  C CD2 . PHE A 1 26  ? 305.973 291.483 90.873  1.00 78.34  ? 26  PHE A CD2 1 
ATOM 107  C CE1 . PHE A 1 26  ? 304.947 289.300 89.521  1.00 78.34  ? 26  PHE A CE1 1 
ATOM 108  C CE2 . PHE A 1 26  ? 306.398 290.207 91.199  1.00 78.34  ? 26  PHE A CE2 1 
ATOM 109  C CZ  . PHE A 1 26  ? 305.884 289.115 90.521  1.00 78.34  ? 26  PHE A CZ  1 
ATOM 110  N N   . ALA A 1 27  ? 302.362 293.814 91.714  1.00 74.45  ? 27  ALA A N   1 
ATOM 111  C CA  . ALA A 1 27  ? 301.721 293.574 93.001  1.00 74.45  ? 27  ALA A CA  1 
ATOM 112  C C   . ALA A 1 27  ? 300.218 293.364 92.848  1.00 74.45  ? 27  ALA A C   1 
ATOM 113  O O   . ALA A 1 27  ? 299.633 292.518 93.536  1.00 74.45  ? 27  ALA A O   1 
ATOM 114  C CB  . ALA A 1 27  ? 302.011 294.736 93.947  1.00 74.45  ? 27  ALA A CB  1 
ATOM 115  N N   . VAL A 1 28  ? 299.579 294.091 91.928  1.00 77.11  ? 28  VAL A N   1 
ATOM 116  C CA  . VAL A 1 28  ? 298.138 293.906 91.783  1.00 77.11  ? 28  VAL A CA  1 
ATOM 117  C C   . VAL A 1 28  ? 297.827 292.611 91.030  1.00 77.11  ? 28  VAL A C   1 
ATOM 118  O O   . VAL A 1 28  ? 296.817 291.958 91.325  1.00 77.11  ? 28  VAL A O   1 
ATOM 119  C CB  . VAL A 1 28  ? 297.460 295.143 91.148  1.00 77.11  ? 28  VAL A CB  1 
ATOM 120  C CG1 . VAL A 1 28  ? 297.621 295.217 89.631  1.00 77.11  ? 28  VAL A CG1 1 
ATOM 121  C CG2 . VAL A 1 28  ? 295.984 295.195 91.534  1.00 77.11  ? 28  VAL A CG2 1 
ATOM 122  N N   . ASP A 1 29  ? 298.703 292.146 90.121  1.00 84.43  ? 29  ASP A N   1 
ATOM 123  C CA  . ASP A 1 29  ? 298.400 290.837 89.549  1.00 84.43  ? 29  ASP A CA  1 
ATOM 124  C C   . ASP A 1 29  ? 298.765 289.710 90.508  1.00 84.43  ? 29  ASP A C   1 
ATOM 125  O O   . ASP A 1 29  ? 298.137 288.652 90.456  1.00 84.43  ? 29  ASP A O   1 
ATOM 126  C CB  . ASP A 1 29  ? 299.050 290.608 88.170  1.00 84.43  ? 29  ASP A CB  1 
ATOM 127  C CG  . ASP A 1 29  ? 300.564 290.741 88.160  1.00 84.43  ? 29  ASP A CG  1 
ATOM 128  O OD1 . ASP A 1 29  ? 301.057 291.614 87.421  1.00 84.43  ? 29  ASP A OD1 1 
ATOM 129  O OD2 . ASP A 1 29  ? 301.270 289.949 88.821  1.00 84.43  ? 29  ASP A OD2 1 
ATOM 130  N N   . GLU A 1 30  ? 299.735 289.919 91.408  1.00 79.56  ? 30  GLU A N   1 
ATOM 131  C CA  . GLU A 1 30  ? 299.967 288.948 92.476  1.00 79.56  ? 30  GLU A CA  1 
ATOM 132  C C   . GLU A 1 30  ? 298.779 288.877 93.431  1.00 79.56  ? 30  GLU A C   1 
ATOM 133  O O   . GLU A 1 30  ? 298.444 287.792 93.928  1.00 79.56  ? 30  GLU A O   1 
ATOM 134  C CB  . GLU A 1 30  ? 301.241 289.298 93.245  1.00 79.56  ? 30  GLU A CB  1 
ATOM 135  C CG  . GLU A 1 30  ? 302.535 288.826 92.602  1.00 79.56  ? 30  GLU A CG  1 
ATOM 136  C CD  . GLU A 1 30  ? 303.764 289.308 93.354  1.00 79.56  ? 30  GLU A CD  1 
ATOM 137  O OE1 . GLU A 1 30  ? 303.985 290.535 93.414  1.00 79.56  ? 30  GLU A OE1 1 
ATOM 138  O OE2 . GLU A 1 30  ? 304.505 288.460 93.892  1.00 79.56  ? 30  GLU A OE2 1 
ATOM 139  N N   . HIS A 1 31  ? 298.126 290.016 93.678  1.00 78.82  ? 31  HIS A N   1 
ATOM 140  C CA  . HIS A 1 31  ? 296.876 290.014 94.433  1.00 78.82  ? 31  HIS A CA  1 
ATOM 141  C C   . HIS A 1 31  ? 295.775 289.276 93.678  1.00 78.82  ? 31  HIS A C   1 
ATOM 142  O O   . HIS A 1 31  ? 294.965 288.566 94.284  1.00 78.82  ? 31  HIS A O   1 
ATOM 143  C CB  . HIS A 1 31  ? 296.446 291.450 94.736  1.00 78.82  ? 31  HIS A CB  1 
ATOM 144  C CG  . HIS A 1 31  ? 295.106 291.553 95.395  1.00 78.82  ? 31  HIS A CG  1 
ATOM 145  N ND1 . HIS A 1 31  ? 294.844 291.015 96.636  1.00 78.82  ? 31  HIS A ND1 1 
ATOM 146  C CD2 . HIS A 1 31  ? 293.953 292.128 94.982  1.00 78.82  ? 31  HIS A CD2 1 
ATOM 147  C CE1 . HIS A 1 31  ? 293.586 291.257 96.961  1.00 78.82  ? 31  HIS A CE1 1 
ATOM 148  N NE2 . HIS A 1 31  ? 293.024 291.931 95.974  1.00 78.82  ? 31  HIS A NE2 1 
ATOM 149  N N   . ASN A 1 32  ? 295.733 289.427 92.353  1.00 82.63  ? 32  ASN A N   1 
ATOM 150  C CA  . ASN A 1 32  ? 294.787 288.656 91.551  1.00 82.63  ? 32  ASN A CA  1 
ATOM 151  C C   . ASN A 1 32  ? 295.144 287.173 91.472  1.00 82.63  ? 32  ASN A C   1 
ATOM 152  O O   . ASN A 1 32  ? 294.287 286.366 91.098  1.00 82.63  ? 32  ASN A O   1 
ATOM 153  C CB  . ASN A 1 32  ? 294.677 289.251 90.146  1.00 82.63  ? 32  ASN A CB  1 
ATOM 154  C CG  . ASN A 1 32  ? 293.824 290.507 90.111  1.00 82.63  ? 32  ASN A CG  1 
ATOM 155  O OD1 . ASN A 1 32  ? 294.046 291.447 90.871  1.00 82.63  ? 32  ASN A OD1 1 
ATOM 156  N ND2 . ASN A 1 32  ? 292.843 290.528 89.216  1.00 82.63  ? 32  ASN A ND2 1 
ATOM 157  N N   . LYS A 1 33  ? 296.390 286.798 91.775  1.00 83.37  ? 33  LYS A N   1 
ATOM 158  C CA  . LYS A 1 33  ? 296.712 285.378 91.922  1.00 83.37  ? 33  LYS A CA  1 
ATOM 159  C C   . LYS A 1 33  ? 296.320 284.831 93.290  1.00 83.37  ? 33  LYS A C   1 
ATOM 160  O O   . LYS A 1 33  ? 295.867 283.685 93.380  1.00 83.37  ? 33  LYS A O   1 
ATOM 161  C CB  . LYS A 1 33  ? 298.204 285.100 91.693  1.00 83.37  ? 33  LYS A CB  1 
ATOM 162  C CG  . LYS A 1 33  ? 298.792 285.549 90.361  1.00 83.37  ? 33  LYS A CG  1 
ATOM 163  C CD  . LYS A 1 33  ? 297.925 285.154 89.179  1.00 83.37  ? 33  LYS A CD  1 
ATOM 164  C CE  . LYS A 1 33  ? 297.884 286.263 88.138  1.00 83.37  ? 33  LYS A CE  1 
ATOM 165  N NZ  . LYS A 1 33  ? 296.807 286.054 87.129  1.00 83.37  ? 33  LYS A NZ  1 
ATOM 166  N N   . LYS A 1 34  ? 296.490 285.612 94.360  1.00 77.78  ? 34  LYS A N   1 
ATOM 167  C CA  . LYS A 1 34  ? 296.247 285.041 95.685  1.00 77.78  ? 34  LYS A CA  1 
ATOM 168  C C   . LYS A 1 34  ? 294.797 285.177 96.152  1.00 77.78  ? 34  LYS A C   1 
ATOM 169  O O   . LYS A 1 34  ? 294.271 284.251 96.779  1.00 77.78  ? 34  LYS A O   1 
ATOM 170  C CB  . LYS A 1 34  ? 297.195 285.651 96.728  1.00 77.78  ? 34  LYS A CB  1 
ATOM 171  C CG  . LYS A 1 34  ? 297.178 287.161 96.852  1.00 77.78  ? 34  LYS A CG  1 
ATOM 172  C CD  . LYS A 1 34  ? 298.472 287.667 97.467  1.00 77.78  ? 34  LYS A CD  1 
ATOM 173  C CE  . LYS A 1 34  ? 298.373 289.133 97.864  1.00 77.78  ? 34  LYS A CE  1 
ATOM 174  N NZ  . LYS A 1 34  ? 299.290 289.457 98.991  1.00 77.78  ? 34  LYS A NZ  1 
ATOM 175  N N   . GLU A 1 35  ? 294.123 286.292 95.858  1.00 80.50  ? 35  GLU A N   1 
ATOM 176  C CA  . GLU A 1 35  ? 292.745 286.481 96.292  1.00 80.50  ? 35  GLU A CA  1 
ATOM 177  C C   . GLU A 1 35  ? 291.735 286.421 95.157  1.00 80.50  ? 35  GLU A C   1 
ATOM 178  O O   . GLU A 1 35  ? 290.530 286.375 95.437  1.00 80.50  ? 35  GLU A O   1 
ATOM 179  C CB  . GLU A 1 35  ? 292.584 287.816 97.036  1.00 80.50  ? 35  GLU A CB  1 
ATOM 180  C CG  . GLU A 1 35  ? 292.743 287.703 98.550  1.00 80.50  ? 35  GLU A CG  1 
ATOM 181  C CD  . GLU A 1 35  ? 294.176 287.878 99.012  1.00 80.50  ? 35  GLU A CD  1 
ATOM 182  O OE1 . GLU A 1 35  ? 294.861 288.789 98.500  1.00 80.50  ? 35  GLU A OE1 1 
ATOM 183  O OE2 . GLU A 1 35  ? 294.618 287.099 99.883  1.00 80.50  ? 35  GLU A OE2 1 
ATOM 184  N N   . ASN A 1 36  ? 292.198 286.453 93.899  1.00 84.61  ? 36  ASN A N   1 
ATOM 185  C CA  . ASN A 1 36  ? 291.416 286.079 92.712  1.00 84.61  ? 36  ASN A CA  1 
ATOM 186  C C   . ASN A 1 36  ? 290.204 286.986 92.501  1.00 84.61  ? 36  ASN A C   1 
ATOM 187  O O   . ASN A 1 36  ? 289.057 286.535 92.512  1.00 84.61  ? 36  ASN A O   1 
ATOM 188  C CB  . ASN A 1 36  ? 291.006 284.607 92.789  1.00 84.61  ? 36  ASN A CB  1 
ATOM 189  C CG  . ASN A 1 36  ? 292.202 283.674 92.725  1.00 84.61  ? 36  ASN A CG  1 
ATOM 190  O OD1 . ASN A 1 36  ? 293.065 283.809 91.858  1.00 84.61  ? 36  ASN A OD1 1 
ATOM 191  N ND2 . ASN A 1 36  ? 292.288 282.759 93.682  1.00 84.61  ? 36  ASN A ND2 1 
ATOM 192  N N   . ALA A 1 37  ? 290.461 288.278 92.313  1.00 84.88  ? 37  ALA A N   1 
ATOM 193  C CA  . ALA A 1 37  ? 289.429 289.285 92.133  1.00 84.88  ? 37  ALA A CA  1 
ATOM 194  C C   . ALA A 1 37  ? 289.775 290.182 90.947  1.00 84.88  ? 37  ALA A C   1 
ATOM 195  O O   . ALA A 1 37  ? 290.684 289.891 90.162  1.00 84.88  ? 37  ALA A O   1 
ATOM 196  C CB  . ALA A 1 37  ? 289.252 290.093 93.419  1.00 84.88  ? 37  ALA A CB  1 
ATOM 197  N N   . LEU A 1 38  ? 289.035 291.282 90.812  1.00 76.90  ? 38  LEU A N   1 
ATOM 198  C CA  . LEU A 1 38  ? 289.243 292.259 89.744  1.00 76.90  ? 38  LEU A CA  1 
ATOM 199  C C   . LEU A 1 38  ? 289.590 293.597 90.398  1.00 76.90  ? 38  LEU A C   1 
ATOM 200  O O   . LEU A 1 38  ? 288.732 294.465 90.565  1.00 76.90  ? 38  LEU A O   1 
ATOM 201  C CB  . LEU A 1 38  ? 287.974 292.355 88.835  1.00 76.90  ? 38  LEU A CB  1 
ATOM 202  C CG  . LEU A 1 38  ? 288.077 292.774 87.360  1.00 76.90  ? 38  LEU A CG  1 
ATOM 203  C CD1 . LEU A 1 38  ? 286.752 292.518 86.658  1.00 76.90  ? 38  LEU A CD1 1 
ATOM 204  C CD2 . LEU A 1 38  ? 288.485 294.231 87.168  1.00 76.90  ? 38  LEU A CD2 1 
ATOM 205  N N   . LEU A 1 39  ? 290.864 293.768 90.741  1.00 80.42  ? 39  LEU A N   1 
ATOM 206  C CA  . LEU A 1 39  ? 291.375 295.016 91.293  1.00 80.42  ? 39  LEU A CA  1 
ATOM 207  C C   . LEU A 1 39  ? 292.187 295.716 90.210  1.00 80.42  ? 39  LEU A C   1 
ATOM 208  O O   . LEU A 1 39  ? 293.147 295.143 89.685  1.00 80.42  ? 39  LEU A O   1 
ATOM 209  C CB  . LEU A 1 39  ? 292.231 294.768 92.537  1.00 80.42  ? 39  LEU A CB  1 
ATOM 210  C CG  . LEU A 1 39  ? 291.591 294.688 93.934  1.00 80.42  ? 39  LEU A CG  1 
ATOM 211  C CD1 . LEU A 1 39  ? 290.925 296.007 94.307  1.00 80.42  ? 39  LEU A CD1 1 
ATOM 212  C CD2 . LEU A 1 39  ? 290.616 293.525 94.085  1.00 80.42  ? 39  LEU A CD2 1 
ATOM 213  N N   . GLU A 1 40  ? 291.804 296.945 89.875  1.00 83.80  ? 40  GLU A N   1 
ATOM 214  C CA  . GLU A 1 40  ? 292.379 297.666 88.741  1.00 83.80  ? 40  GLU A CA  1 
ATOM 215  C C   . GLU A 1 40  ? 293.255 298.791 89.283  1.00 83.80  ? 40  GLU A C   1 
ATOM 216  O O   . GLU A 1 40  ? 292.749 299.787 89.807  1.00 83.80  ? 40  GLU A O   1 
ATOM 217  C CB  . GLU A 1 40  ? 291.275 298.190 87.825  1.00 83.80  ? 40  GLU A CB  1 
ATOM 218  C CG  . GLU A 1 40  ? 291.765 298.778 86.511  1.00 83.80  ? 40  GLU A CG  1 
ATOM 219  C CD  . GLU A 1 40  ? 291.656 300.286 86.455  1.00 83.80  ? 40  GLU A CD  1 
ATOM 220  O OE1 . GLU A 1 40  ? 290.652 300.832 86.956  1.00 83.80  ? 40  GLU A OE1 1 
ATOM 221  O OE2 . GLU A 1 40  ? 292.571 300.924 85.895  1.00 83.80  ? 40  GLU A OE2 1 
ATOM 222  N N   . PHE A 1 41  ? 294.570 298.620 89.167  1.00 81.46  ? 41  PHE A N   1 
ATOM 223  C CA  . PHE A 1 41  ? 295.509 299.629 89.642  1.00 81.46  ? 41  PHE A CA  1 
ATOM 224  C C   . PHE A 1 41  ? 295.481 300.843 88.722  1.00 81.46  ? 41  PHE A C   1 
ATOM 225  O O   . PHE A 1 41  ? 295.481 300.705 87.495  1.00 81.46  ? 41  PHE A O   1 
ATOM 226  C CB  . PHE A 1 41  ? 296.917 299.039 89.718  1.00 81.46  ? 41  PHE A CB  1 
ATOM 227  C CG  . PHE A 1 41  ? 298.008 300.068 89.809  1.00 81.46  ? 41  PHE A CG  1 
ATOM 228  C CD1 . PHE A 1 41  ? 298.230 300.752 90.992  1.00 81.46  ? 41  PHE A CD1 1 
ATOM 229  C CD2 . PHE A 1 41  ? 298.824 300.337 88.716  1.00 81.46  ? 41  PHE A CD2 1 
ATOM 230  C CE1 . PHE A 1 41  ? 299.236 301.695 91.082  1.00 81.46  ? 41  PHE A CE1 1 
ATOM 231  C CE2 . PHE A 1 41  ? 299.830 301.283 88.799  1.00 81.46  ? 41  PHE A CE2 1 
ATOM 232  C CZ  . PHE A 1 41  ? 300.033 301.964 89.983  1.00 81.46  ? 41  PHE A CZ  1 
ATOM 233  N N   . VAL A 1 42  ? 295.448 302.037 89.314  1.00 87.26  ? 42  VAL A N   1 
ATOM 234  C CA  . VAL A 1 42  ? 295.391 303.287 88.566  1.00 87.26  ? 42  VAL A CA  1 
ATOM 235  C C   . VAL A 1 42  ? 296.607 304.169 88.835  1.00 87.26  ? 42  VAL A C   1 
ATOM 236  O O   . VAL A 1 42  ? 297.237 304.674 87.901  1.00 87.26  ? 42  VAL A O   1 
ATOM 237  C CB  . VAL A 1 42  ? 294.078 304.055 88.848  1.00 87.26  ? 42  VAL A CB  1 
ATOM 238  C CG1 . VAL A 1 42  ? 292.969 303.520 87.973  1.00 87.26  ? 42  VAL A CG1 1 
ATOM 239  C CG2 . VAL A 1 42  ? 293.668 303.909 90.306  1.00 87.26  ? 42  VAL A CG2 1 
ATOM 240  N N   . ARG A 1 43  ? 296.966 304.351 90.105  1.00 93.45  ? 43  ARG A N   1 
ATOM 241  C CA  . ARG A 1 43  ? 298.004 305.313 90.444  1.00 93.45  ? 43  ARG A CA  1 
ATOM 242  C C   . ARG A 1 43  ? 298.608 304.968 91.798  1.00 93.45  ? 43  ARG A C   1 
ATOM 243  O O   . ARG A 1 43  ? 297.915 304.475 92.691  1.00 93.45  ? 43  ARG A O   1 
ATOM 244  C CB  . ARG A 1 43  ? 297.457 306.749 90.459  1.00 93.45  ? 43  ARG A CB  1 
ATOM 245  C CG  . ARG A 1 43  ? 296.248 306.961 91.359  1.00 93.45  ? 43  ARG A CG  1 
ATOM 246  C CD  . ARG A 1 43  ? 295.973 308.440 91.572  1.00 93.45  ? 43  ARG A CD  1 
ATOM 247  N NE  . ARG A 1 43  ? 295.382 308.701 92.880  1.00 93.45  ? 43  ARG A NE  1 
ATOM 248  C CZ  . ARG A 1 43  ? 295.045 309.909 93.320  1.00 93.45  ? 43  ARG A CZ  1 
ATOM 249  N NH1 . ARG A 1 43  ? 295.238 310.975 92.556  1.00 93.45  ? 43  ARG A NH1 1 
ATOM 250  N NH2 . ARG A 1 43  ? 294.514 310.052 94.526  1.00 93.45  ? 43  ARG A NH2 1 
ATOM 251  N N   . VAL A 1 44  ? 299.908 305.207 91.920  1.00 79.95  ? 44  VAL A N   1 
ATOM 252  C CA  . VAL A 1 44  ? 300.610 305.055 93.188  1.00 79.95  ? 44  VAL A CA  1 
ATOM 253  C C   . VAL A 1 44  ? 300.300 306.260 94.064  1.00 79.95  ? 44  VAL A C   1 
ATOM 254  O O   . VAL A 1 44  ? 300.461 307.410 93.637  1.00 79.95  ? 44  VAL A O   1 
ATOM 255  C CB  . VAL A 1 44  ? 302.121 304.907 92.952  1.00 79.95  ? 44  VAL A CB  1 
ATOM 256  C CG1 . VAL A 1 44  ? 302.889 305.028 94.257  1.00 79.95  ? 44  VAL A CG1 1 
ATOM 257  C CG2 . VAL A 1 44  ? 302.421 303.581 92.274  1.00 79.95  ? 44  VAL A CG2 1 
ATOM 258  N N   . VAL A 1 45  ? 299.844 306.005 95.289  1.00 77.79  ? 45  VAL A N   1 
ATOM 259  C CA  . VAL A 1 45  ? 299.453 307.081 96.192  1.00 77.79  ? 45  VAL A CA  1 
ATOM 260  C C   . VAL A 1 45  ? 300.675 307.591 96.945  1.00 77.79  ? 45  VAL A C   1 
ATOM 261  O O   . VAL A 1 45  ? 301.056 308.760 96.812  1.00 77.79  ? 45  VAL A O   1 
ATOM 262  C CB  . VAL A 1 45  ? 298.355 306.605 97.158  1.00 77.79  ? 45  VAL A CB  1 
ATOM 263  C CG1 . VAL A 1 45  ? 297.831 307.762 97.979  1.00 77.79  ? 45  VAL A CG1 1 
ATOM 264  C CG2 . VAL A 1 45  ? 297.228 305.947 96.383  1.00 77.79  ? 45  VAL A CG2 1 
ATOM 265  N N   . LYS A 1 46  ? 301.296 306.725 97.741  1.00 72.35  ? 46  LYS A N   1 
ATOM 266  C CA  . LYS A 1 46  ? 302.555 307.031 98.404  1.00 72.35  ? 46  LYS A CA  1 
ATOM 267  C C   . LYS A 1 46  ? 303.581 305.959 98.057  1.00 72.35  ? 46  LYS A C   1 
ATOM 268  O O   . LYS A 1 46  ? 303.234 304.859 97.616  1.00 72.35  ? 46  LYS A O   1 
ATOM 269  C CB  . LYS A 1 46  ? 302.400 307.126 99.931  1.00 72.35  ? 46  LYS A CB  1 
ATOM 270  C CG  . LYS A 1 46  ? 301.093 307.725 100.429 1.00 72.35  ? 46  LYS A CG  1 
ATOM 271  C CD  . LYS A 1 46  ? 301.003 309.219 100.152 1.00 72.35  ? 46  LYS A CD  1 
ATOM 272  C CE  . LYS A 1 46  ? 299.631 309.768 100.527 1.00 72.35  ? 46  LYS A CE  1 
ATOM 273  N NZ  . LYS A 1 46  ? 299.705 311.122 101.140 1.00 72.35  ? 46  LYS A NZ  1 
ATOM 274  N N   . ALA A 1 47  ? 304.853 306.292 98.268  1.00 66.44  ? 47  ALA A N   1 
ATOM 275  C CA  . ALA A 1 47  ? 305.948 305.384 97.930  1.00 66.44  ? 47  ALA A CA  1 
ATOM 276  C C   . ALA A 1 47  ? 307.163 305.743 98.768  1.00 66.44  ? 47  ALA A C   1 
ATOM 277  O O   . ALA A 1 47  ? 307.518 306.922 98.870  1.00 66.44  ? 47  ALA A O   1 
ATOM 278  C CB  . ALA A 1 47  ? 306.281 305.458 96.440  1.00 66.44  ? 47  ALA A CB  1 
ATOM 279  N N   . LYS A 1 48  ? 307.795 304.734 99.363  1.00 68.70  ? 48  LYS A N   1 
ATOM 280  C CA  . LYS A 1 48  ? 309.030 304.893 100.119 1.00 68.70  ? 48  LYS A CA  1 
ATOM 281  C C   . LYS A 1 48  ? 310.052 303.906 99.572  1.00 68.70  ? 48  LYS A C   1 
ATOM 282  O O   . LYS A 1 48  ? 309.732 302.733 99.361  1.00 68.70  ? 48  LYS A O   1 
ATOM 283  C CB  . LYS A 1 48  ? 308.787 304.659 101.615 1.00 68.70  ? 48  LYS A CB  1 
ATOM 284  C CG  . LYS A 1 48  ? 310.012 304.788 102.514 1.00 68.70  ? 48  LYS A CG  1 
ATOM 285  C CD  . LYS A 1 48  ? 310.826 306.044 102.228 1.00 68.70  ? 48  LYS A CD  1 
ATOM 286  C CE  . LYS A 1 48  ? 312.056 306.112 103.115 1.00 68.70  ? 48  LYS A CE  1 
ATOM 287  N NZ  . LYS A 1 48  ? 313.235 306.640 102.380 1.00 68.70  ? 48  LYS A NZ  1 
ATOM 288  N N   . GLU A 1 49  ? 311.273 304.383 99.329  1.00 77.91  ? 49  GLU A N   1 
ATOM 289  C CA  . GLU A 1 49  ? 312.356 303.567 98.786  1.00 77.91  ? 49  GLU A CA  1 
ATOM 290  C C   . GLU A 1 49  ? 313.439 303.434 99.854  1.00 77.91  ? 49  GLU A C   1 
ATOM 291  O O   . GLU A 1 49  ? 314.086 304.423 100.214 1.00 77.91  ? 49  GLU A O   1 
ATOM 292  C CB  . GLU A 1 49  ? 312.914 304.194 97.509  1.00 77.91  ? 49  GLU A CB  1 
ATOM 293  C CG  . GLU A 1 49  ? 311.927 304.226 96.348  1.00 77.91  ? 49  GLU A CG  1 
ATOM 294  C CD  . GLU A 1 49  ? 312.597 304.057 94.997  1.00 77.91  ? 49  GLU A CD  1 
ATOM 295  O OE1 . GLU A 1 49  ? 313.708 304.597 94.807  1.00 77.91  ? 49  GLU A OE1 1 
ATOM 296  O OE2 . GLU A 1 49  ? 312.004 303.402 94.116  1.00 77.91  ? 49  GLU A OE2 1 
ATOM 297  N N   . GLN A 1 50  ? 313.635 302.216 100.359 1.00 75.18  ? 50  GLN A N   1 
ATOM 298  C CA  . GLN A 1 50  ? 314.579 301.951 101.438 1.00 75.18  ? 50  GLN A CA  1 
ATOM 299  C C   . GLN A 1 50  ? 315.557 300.862 101.029 1.00 75.18  ? 50  GLN A C   1 
ATOM 300  O O   . GLN A 1 50  ? 315.143 299.786 100.588 1.00 75.18  ? 50  GLN A O   1 
ATOM 301  C CB  . GLN A 1 50  ? 313.864 301.511 102.717 1.00 75.18  ? 50  GLN A CB  1 
ATOM 302  C CG  . GLN A 1 50  ? 312.785 302.436 103.205 1.00 75.18  ? 50  GLN A CG  1 
ATOM 303  C CD  . GLN A 1 50  ? 312.031 301.846 104.366 1.00 75.18  ? 50  GLN A CD  1 
ATOM 304  O OE1 . GLN A 1 50  ? 310.809 301.771 104.350 1.00 75.18  ? 50  GLN A OE1 1 
ATOM 305  N NE2 . GLN A 1 50  ? 312.761 301.414 105.385 1.00 75.18  ? 50  GLN A NE2 1 
ATOM 306  N N   . ILE A 1 51  ? 316.851 301.128 101.203 1.00 77.30  ? 51  ILE A N   1 
ATOM 307  C CA  . ILE A 1 51  ? 317.836 300.073 101.006 1.00 77.30  ? 51  ILE A CA  1 
ATOM 308  C C   . ILE A 1 51  ? 317.842 299.138 102.212 1.00 77.30  ? 51  ILE A C   1 
ATOM 309  O O   . ILE A 1 51  ? 317.394 299.481 103.314 1.00 77.30  ? 51  ILE A O   1 
ATOM 310  C CB  . ILE A 1 51  ? 319.235 300.660 100.754 1.00 77.30  ? 51  ILE A CB  1 
ATOM 311  C CG1 . ILE A 1 51  ? 319.698 301.466 101.970 1.00 77.30  ? 51  ILE A CG1 1 
ATOM 312  C CG2 . ILE A 1 51  ? 319.238 301.517 99.495  1.00 77.30  ? 51  ILE A CG2 1 
ATOM 313  C CD1 . ILE A 1 51  ? 321.196 301.504 102.142 1.00 77.30  ? 51  ILE A CD1 1 
ATOM 314  N N   . ILE A 1 52  ? 318.344 297.929 101.990 1.00 75.45  ? 52  ILE A N   1 
ATOM 315  C CA  . ILE A 1 52  ? 318.563 296.986 103.077 1.00 75.45  ? 52  ILE A CA  1 
ATOM 316  C C   . ILE A 1 52  ? 320.054 296.693 103.173 1.00 75.45  ? 52  ILE A C   1 
ATOM 317  O O   . ILE A 1 52  ? 320.846 297.192 102.372 1.00 75.45  ? 52  ILE A O   1 
ATOM 318  C CB  . ILE A 1 52  ? 317.752 295.685 102.891 1.00 75.45  ? 52  ILE A CB  1 
ATOM 319  C CG1 . ILE A 1 52  ? 316.263 295.997 102.676 1.00 75.45  ? 52  ILE A CG1 1 
ATOM 320  C CG2 . ILE A 1 52  ? 317.984 294.753 104.079 1.00 75.45  ? 52  ILE A CG2 1 
ATOM 321  C CD1 . ILE A 1 52  ? 315.335 294.794 102.791 1.00 75.45  ? 52  ILE A CD1 1 
ATOM 322  N N   . ASP A 1 59  ? 319.280 294.090 97.543  1.00 74.99  ? 59  ASP A N   1 
ATOM 323  C CA  . ASP A 1 59  ? 318.236 294.124 98.554  1.00 74.99  ? 59  ASP A CA  1 
ATOM 324  C C   . ASP A 1 59  ? 317.749 295.551 98.812  1.00 74.99  ? 59  ASP A C   1 
ATOM 325  O O   . ASP A 1 59  ? 318.487 296.413 99.299  1.00 74.99  ? 59  ASP A O   1 
ATOM 326  C CB  . ASP A 1 59  ? 318.730 293.447 99.845  1.00 74.99  ? 59  ASP A CB  1 
ATOM 327  C CG  . ASP A 1 59  ? 320.062 293.993 100.326 1.00 74.99  ? 59  ASP A CG  1 
ATOM 328  O OD1 . ASP A 1 59  ? 320.299 293.993 101.550 1.00 74.99  ? 59  ASP A OD1 1 
ATOM 329  O OD2 . ASP A 1 59  ? 320.873 294.422 99.476  1.00 74.99  ? 59  ASP A OD2 1 
ATOM 330  N N   . THR A 1 60  ? 316.495 295.798 98.446  1.00 80.13  ? 60  THR A N   1 
ATOM 331  C CA  . THR A 1 60  ? 315.910 297.129 98.546  1.00 80.13  ? 60  THR A CA  1 
ATOM 332  C C   . THR A 1 60  ? 314.443 296.989 98.929  1.00 80.13  ? 60  THR A C   1 
ATOM 333  O O   . THR A 1 60  ? 313.679 296.323 98.224  1.00 80.13  ? 60  THR A O   1 
ATOM 334  C CB  . THR A 1 60  ? 316.057 297.890 97.221  1.00 80.13  ? 60  THR A CB  1 
ATOM 335  O OG1 . THR A 1 60  ? 317.445 297.998 96.876  1.00 80.13  ? 60  THR A OG1 1 
ATOM 336  C CG2 . THR A 1 60  ? 315.462 299.282 97.334  1.00 80.13  ? 60  THR A CG2 1 
ATOM 337  N N   . MET A 1 61  ? 314.059 297.621 100.035 1.00 78.36  ? 61  MET A N   1 
ATOM 338  C CA  . MET A 1 61  ? 312.713 297.534 100.583 1.00 78.36  ? 61  MET A CA  1 
ATOM 339  C C   . MET A 1 61  ? 311.857 298.691 100.078 1.00 78.36  ? 61  MET A C   1 
ATOM 340  O O   . MET A 1 61  ? 312.351 299.793 99.833  1.00 78.36  ? 61  MET A O   1 
ATOM 341  C CB  . MET A 1 61  ? 312.757 297.542 102.117 1.00 78.36  ? 61  MET A CB  1 
ATOM 342  C CG  . MET A 1 61  ? 311.467 297.135 102.861 1.00 78.36  ? 61  MET A CG  1 
ATOM 343  S SD  . MET A 1 61  ? 310.951 295.400 102.760 1.00 78.36  ? 61  MET A SD  1 
ATOM 344  C CE  . MET A 1 61  ? 309.845 295.373 101.346 1.00 78.36  ? 61  MET A CE  1 
ATOM 345  N N   . TYR A 1 62  ? 310.560 298.428 99.922  1.00 79.46  ? 62  TYR A N   1 
ATOM 346  C CA  . TYR A 1 62  ? 309.625 299.428 99.433  1.00 79.46  ? 62  TYR A CA  1 
ATOM 347  C C   . TYR A 1 62  ? 308.359 299.412 100.272 1.00 79.46  ? 62  TYR A C   1 
ATOM 348  O O   . TYR A 1 62  ? 307.832 298.344 100.592 1.00 79.46  ? 62  TYR A O   1 
ATOM 349  C CB  . TYR A 1 62  ? 309.266 299.186 97.962  1.00 79.46  ? 62  TYR A CB  1 
ATOM 350  C CG  . TYR A 1 62  ? 310.440 299.288 97.020  1.00 79.46  ? 62  TYR A CG  1 
ATOM 351  C CD1 . TYR A 1 62  ? 311.160 298.159 96.653  1.00 79.46  ? 62  TYR A CD1 1 
ATOM 352  C CD2 . TYR A 1 62  ? 310.830 300.514 96.498  1.00 79.46  ? 62  TYR A CD2 1 
ATOM 353  C CE1 . TYR A 1 62  ? 312.234 298.250 95.792  1.00 79.46  ? 62  TYR A CE1 1 
ATOM 354  C CE2 . TYR A 1 62  ? 311.904 300.613 95.635  1.00 79.46  ? 62  TYR A CE2 1 
ATOM 355  C CZ  . TYR A 1 62  ? 312.600 299.479 95.283  1.00 79.46  ? 62  TYR A CZ  1 
ATOM 356  O OH  . TYR A 1 62  ? 313.671 299.579 94.424  1.00 79.46  ? 62  TYR A OH  1 
ATOM 357  N N   . TYR A 1 63  ? 307.871 300.601 100.619 1.00 66.67  ? 63  TYR A N   1 
ATOM 358  C CA  . TYR A 1 63  ? 306.579 300.773 101.287 1.00 66.67  ? 63  TYR A CA  1 
ATOM 359  C C   . TYR A 1 63  ? 305.647 301.396 100.250 1.00 66.67  ? 63  TYR A C   1 
ATOM 360  O O   . TYR A 1 63  ? 305.515 302.618 100.169 1.00 66.67  ? 63  TYR A O   1 
ATOM 361  C CB  . TYR A 1 63  ? 306.681 301.653 102.542 1.00 66.67  ? 63  TYR A CB  1 
ATOM 362  C CG  . TYR A 1 63  ? 307.412 301.067 103.744 1.00 66.67  ? 63  TYR A CG  1 
ATOM 363  C CD1 . TYR A 1 63  ? 307.499 301.788 104.928 1.00 66.67  ? 63  TYR A CD1 1 
ATOM 364  C CD2 . TYR A 1 63  ? 308.011 299.808 103.701 1.00 66.67  ? 63  TYR A CD2 1 
ATOM 365  C CE1 . TYR A 1 63  ? 308.152 301.276 106.035 1.00 66.67  ? 63  TYR A CE1 1 
ATOM 366  C CE2 . TYR A 1 63  ? 308.678 299.294 104.802 1.00 66.67  ? 63  TYR A CE2 1 
ATOM 367  C CZ  . TYR A 1 63  ? 308.740 300.030 105.965 1.00 66.67  ? 63  TYR A CZ  1 
ATOM 368  O OH  . TYR A 1 63  ? 309.394 299.521 107.063 1.00 66.67  ? 63  TYR A OH  1 
ATOM 369  N N   . LEU A 1 64  ? 304.997 300.546 99.455  1.00 68.65  ? 64  LEU A N   1 
ATOM 370  C CA  . LEU A 1 64  ? 304.259 300.982 98.273  1.00 68.65  ? 64  LEU A CA  1 
ATOM 371  C C   . LEU A 1 64  ? 302.783 301.133 98.624  1.00 68.65  ? 64  LEU A C   1 
ATOM 372  O O   . LEU A 1 64  ? 302.084 300.141 98.860  1.00 68.65  ? 64  LEU A O   1 
ATOM 373  C CB  . LEU A 1 64  ? 304.447 300.000 97.119  1.00 68.65  ? 64  LEU A CB  1 
ATOM 374  C CG  . LEU A 1 64  ? 303.532 300.153 95.899  1.00 68.65  ? 64  LEU A CG  1 
ATOM 375  C CD1 . LEU A 1 64  ? 303.652 301.530 95.264  1.00 68.65  ? 64  LEU A CD1 1 
ATOM 376  C CD2 . LEU A 1 64  ? 303.838 299.084 94.886  1.00 68.65  ? 64  LEU A CD2 1 
ATOM 377  N N   . THR A 1 65  ? 302.313 302.375 98.662  1.00 72.80  ? 65  THR A N   1 
ATOM 378  C CA  . THR A 1 65  ? 300.889 302.661 98.793  1.00 72.80  ? 65  THR A CA  1 
ATOM 379  C C   . THR A 1 65  ? 300.331 302.867 97.392  1.00 72.80  ? 65  THR A C   1 
ATOM 380  O O   . THR A 1 65  ? 300.487 303.936 96.798  1.00 72.80  ? 65  THR A O   1 
ATOM 381  C CB  . THR A 1 65  ? 300.660 303.883 99.672  1.00 72.80  ? 65  THR A CB  1 
ATOM 382  O OG1 . THR A 1 65  ? 301.299 303.688 100.940 1.00 72.80  ? 65  THR A OG1 1 
ATOM 383  C CG2 . THR A 1 65  ? 299.174 304.118 99.879  1.00 72.80  ? 65  THR A CG2 1 
ATOM 384  N N   . LEU A 1 66  ? 299.693 301.834 96.854  1.00 77.44  ? 66  LEU A N   1 
ATOM 385  C CA  . LEU A 1 66  ? 299.081 301.893 95.537  1.00 77.44  ? 66  LEU A CA  1 
ATOM 386  C C   . LEU A 1 66  ? 297.571 301.978 95.692  1.00 77.44  ? 66  LEU A C   1 
ATOM 387  O O   . LEU A 1 66  ? 297.014 301.590 96.722  1.00 77.44  ? 66  LEU A O   1 
ATOM 388  C CB  . LEU A 1 66  ? 299.441 300.669 94.684  1.00 77.44  ? 66  LEU A CB  1 
ATOM 389  C CG  . LEU A 1 66  ? 298.665 299.349 94.822  1.00 77.44  ? 66  LEU A CG  1 
ATOM 390  C CD1 . LEU A 1 66  ? 299.125 298.374 93.746  1.00 77.44  ? 66  LEU A CD1 1 
ATOM 391  C CD2 . LEU A 1 66  ? 298.771 298.699 96.196  1.00 77.44  ? 66  LEU A CD2 1 
ATOM 392  N N   . GLU A 1 67  ? 296.908 302.492 94.666  1.00 81.61  ? 67  GLU A N   1 
ATOM 393  C CA  . GLU A 1 67  ? 295.456 302.505 94.632  1.00 81.61  ? 67  GLU A CA  1 
ATOM 394  C C   . GLU A 1 67  ? 295.003 301.484 93.601  1.00 81.61  ? 67  GLU A C   1 
ATOM 395  O O   . GLU A 1 67  ? 295.390 301.563 92.430  1.00 81.61  ? 67  GLU A O   1 
ATOM 396  C CB  . GLU A 1 67  ? 294.914 303.895 94.296  1.00 81.61  ? 67  GLU A CB  1 
ATOM 397  C CG  . GLU A 1 67  ? 293.613 304.232 95.023  1.00 81.61  ? 67  GLU A CG  1 
ATOM 398  C CD  . GLU A 1 67  ? 292.384 303.558 94.445  1.00 81.61  ? 67  GLU A CD  1 
ATOM 399  O OE1 . GLU A 1 67  ? 292.413 303.099 93.286  1.00 81.61  ? 67  GLU A OE1 1 
ATOM 400  O OE2 . GLU A 1 67  ? 291.382 303.463 95.179  1.00 81.61  ? 67  GLU A OE2 1 
ATOM 401  N N   . ALA A 1 68  ? 294.189 300.529 94.039  1.00 77.74  ? 68  ALA A N   1 
ATOM 402  C CA  . ALA A 1 68  ? 293.645 299.497 93.166  1.00 77.74  ? 68  ALA A CA  1 
ATOM 403  C C   . ALA A 1 68  ? 292.136 299.676 93.123  1.00 77.74  ? 68  ALA A C   1 
ATOM 404  O O   . ALA A 1 68  ? 291.442 299.335 94.087  1.00 77.74  ? 68  ALA A O   1 
ATOM 405  C CB  . ALA A 1 68  ? 294.023 298.098 93.655  1.00 77.74  ? 68  ALA A CB  1 
ATOM 406  N N   . LYS A 1 69  ? 291.639 300.226 92.019  1.00 82.79  ? 69  LYS A N   1 
ATOM 407  C CA  . LYS A 1 69  ? 290.207 300.426 91.852  1.00 82.79  ? 69  LYS A CA  1 
ATOM 408  C C   . LYS A 1 69  ? 289.499 299.085 91.694  1.00 82.79  ? 69  LYS A C   1 
ATOM 409  O O   . LYS A 1 69  ? 290.032 298.140 91.106  1.00 82.79  ? 69  LYS A O   1 
ATOM 410  C CB  . LYS A 1 69  ? 289.933 301.312 90.638  1.00 82.79  ? 69  LYS A CB  1 
ATOM 411  C CG  . LYS A 1 69  ? 288.614 302.056 90.680  1.00 82.79  ? 69  LYS A CG  1 
ATOM 412  C CD  . LYS A 1 69  ? 288.221 302.538 89.293  1.00 82.79  ? 69  LYS A CD  1 
ATOM 413  C CE  . LYS A 1 69  ? 289.286 303.446 88.698  1.00 82.79  ? 69  LYS A CE  1 
ATOM 414  N NZ  . LYS A 1 69  ? 289.305 303.385 87.211  1.00 82.79  ? 69  LYS A NZ  1 
ATOM 415  N N   . ASP A 1 70  ? 288.282 299.010 92.233  1.00 81.66  ? 70  ASP A N   1 
ATOM 416  C CA  . ASP A 1 70  ? 287.513 297.766 92.304  1.00 81.66  ? 70  ASP A CA  1 
ATOM 417  C C   . ASP A 1 70  ? 286.188 297.963 91.575  1.00 81.66  ? 70  ASP A C   1 
ATOM 418  O O   . ASP A 1 70  ? 285.165 298.246 92.201  1.00 81.66  ? 70  ASP A O   1 
ATOM 419  C CB  . ASP A 1 70  ? 287.301 297.365 93.757  1.00 81.66  ? 70  ASP A CB  1 
ATOM 420  C CG  . ASP A 1 70  ? 287.136 295.875 93.936  1.00 81.66  ? 70  ASP A CG  1 
ATOM 421  O OD1 . ASP A 1 70  ? 287.820 295.107 93.234  1.00 81.66  ? 70  ASP A OD1 1 
ATOM 422  O OD2 . ASP A 1 70  ? 286.315 295.472 94.785  1.00 81.66  ? 70  ASP A OD2 1 
ATOM 423  N N   . GLY A 1 71  ? 286.212 297.791 90.254  1.00 69.90  ? 71  GLY A N   1 
ATOM 424  C CA  . GLY A 1 71  ? 284.998 297.836 89.457  1.00 69.90  ? 71  GLY A CA  1 
ATOM 425  C C   . GLY A 1 71  ? 284.279 299.166 89.425  1.00 69.90  ? 71  GLY A C   1 
ATOM 426  O O   . GLY A 1 71  ? 283.071 299.199 89.176  1.00 69.90  ? 71  GLY A O   1 
ATOM 427  N N   . GLY A 1 72  ? 284.982 300.266 89.680  1.00 71.04  ? 72  GLY A N   1 
ATOM 428  C CA  . GLY A 1 72  ? 284.376 301.579 89.726  1.00 71.04  ? 72  GLY A CA  1 
ATOM 429  C C   . GLY A 1 72  ? 284.387 302.230 91.090  1.00 71.04  ? 72  GLY A C   1 
ATOM 430  O O   . GLY A 1 72  ? 284.138 303.439 91.180  1.00 71.04  ? 72  GLY A O   1 
ATOM 431  N N   . LYS A 1 73  ? 284.661 301.482 92.154  1.00 82.71  ? 73  LYS A N   1 
ATOM 432  C CA  . LYS A 1 73  ? 284.796 302.050 93.485  1.00 82.71  ? 73  LYS A CA  1 
ATOM 433  C C   . LYS A 1 73  ? 286.264 302.050 93.893  1.00 82.71  ? 73  LYS A C   1 
ATOM 434  O O   . LYS A 1 73  ? 287.037 301.169 93.497  1.00 82.71  ? 73  LYS A O   1 
ATOM 435  C CB  . LYS A 1 73  ? 283.936 301.298 94.512  1.00 82.71  ? 73  LYS A CB  1 
ATOM 436  C CG  . LYS A 1 73  ? 284.432 299.928 94.941  1.00 82.71  ? 73  LYS A CG  1 
ATOM 437  C CD  . LYS A 1 73  ? 283.290 299.083 95.469  1.00 82.71  ? 73  LYS A CD  1 
ATOM 438  C CE  . LYS A 1 73  ? 282.369 298.645 94.344  1.00 82.71  ? 73  LYS A CE  1 
ATOM 439  N NZ  . LYS A 1 73  ? 283.082 297.788 93.359  1.00 82.71  ? 73  LYS A NZ  1 
ATOM 440  N N   . LYS A 1 74  ? 286.648 303.067 94.655  1.00 83.99  ? 74  LYS A N   1 
ATOM 441  C CA  . LYS A 1 74  ? 288.039 303.309 95.006  1.00 83.99  ? 74  LYS A CA  1 
ATOM 442  C C   . LYS A 1 74  ? 288.243 303.065 96.493  1.00 83.99  ? 74  LYS A C   1 
ATOM 443  O O   . LYS A 1 74  ? 287.439 303.517 97.315  1.00 83.99  ? 74  LYS A O   1 
ATOM 444  C CB  . LYS A 1 74  ? 288.442 304.740 94.647  1.00 83.99  ? 74  LYS A CB  1 
ATOM 445  C CG  . LYS A 1 74  ? 288.636 304.976 93.163  1.00 83.99  ? 74  LYS A CG  1 
ATOM 446  C CD  . LYS A 1 74  ? 288.658 306.460 92.838  1.00 83.99  ? 74  LYS A CD  1 
ATOM 447  C CE  . LYS A 1 74  ? 288.548 306.698 91.344  1.00 83.99  ? 74  LYS A CE  1 
ATOM 448  N NZ  . LYS A 1 74  ? 287.678 305.677 90.704  1.00 83.99  ? 74  LYS A NZ  1 
ATOM 449  N N   . LYS A 1 75  ? 289.309 302.344 96.836  1.00 81.36  ? 75  LYS A N   1 
ATOM 450  C CA  . LYS A 1 75  ? 289.710 302.193 98.227  1.00 81.36  ? 75  LYS A CA  1 
ATOM 451  C C   . LYS A 1 75  ? 291.223 302.095 98.331  1.00 81.36  ? 75  LYS A C   1 
ATOM 452  O O   . LYS A 1 75  ? 291.878 301.489 97.479  1.00 81.36  ? 75  LYS A O   1 
ATOM 453  C CB  . LYS A 1 75  ? 289.054 300.976 98.892  1.00 81.36  ? 75  LYS A CB  1 
ATOM 454  C CG  . LYS A 1 75  ? 288.671 299.840 97.975  1.00 81.36  ? 75  LYS A CG  1 
ATOM 455  C CD  . LYS A 1 75  ? 288.254 298.644 98.815  1.00 81.36  ? 75  LYS A CD  1 
ATOM 456  C CE  . LYS A 1 75  ? 287.932 297.439 97.958  1.00 81.36  ? 75  LYS A CE  1 
ATOM 457  N NZ  . LYS A 1 75  ? 286.796 297.734 97.048  1.00 81.36  ? 75  LYS A NZ  1 
ATOM 458  N N   . LEU A 1 76  ? 291.760 302.702 99.388  1.00 76.59  ? 76  LEU A N   1 
ATOM 459  C CA  . LEU A 1 76  ? 293.201 302.764 99.595  1.00 76.59  ? 76  LEU A CA  1 
ATOM 460  C C   . LEU A 1 76  ? 293.744 301.395 99.978  1.00 76.59  ? 76  LEU A C   1 
ATOM 461  O O   . LEU A 1 76  ? 293.271 300.772 100.934 1.00 76.59  ? 76  LEU A O   1 
ATOM 462  C CB  . LEU A 1 76  ? 293.529 303.782 100.686 1.00 76.59  ? 76  LEU A CB  1 
ATOM 463  C CG  . LEU A 1 76  ? 294.781 304.645 100.519 1.00 76.59  ? 76  LEU A CG  1 
ATOM 464  C CD1 . LEU A 1 76  ? 294.765 305.378 99.190  1.00 76.59  ? 76  LEU A CD1 1 
ATOM 465  C CD2 . LEU A 1 76  ? 294.893 305.627 101.668 1.00 76.59  ? 76  LEU A CD2 1 
ATOM 466  N N   . TYR A 1 77  ? 294.745 300.932 99.233  1.00 78.27  ? 77  TYR A N   1 
ATOM 467  C CA  . TYR A 1 77  ? 295.343 299.621 99.427  1.00 78.27  ? 77  TYR A CA  1 
ATOM 468  C C   . TYR A 1 77  ? 296.851 299.775 99.588  1.00 78.27  ? 77  TYR A C   1 
ATOM 469  O O   . TYR A 1 77  ? 297.393 300.884 99.537  1.00 78.27  ? 77  TYR A O   1 
ATOM 470  C CB  . TYR A 1 77  ? 294.989 298.690 98.265  1.00 78.27  ? 77  TYR A CB  1 
ATOM 471  C CG  . TYR A 1 77  ? 293.741 297.884 98.520  1.00 78.27  ? 77  TYR A CG  1 
ATOM 472  C CD1 . TYR A 1 77  ? 292.737 297.787 97.563  1.00 78.27  ? 77  TYR A CD1 1 
ATOM 473  C CD2 . TYR A 1 77  ? 293.567 297.218 99.724  1.00 78.27  ? 77  TYR A CD2 1 
ATOM 474  C CE1 . TYR A 1 77  ? 291.598 297.039 97.802  1.00 78.27  ? 77  TYR A CE1 1 
ATOM 475  C CE2 . TYR A 1 77  ? 292.436 296.474 99.970  1.00 78.27  ? 77  TYR A CE2 1 
ATOM 476  C CZ  . TYR A 1 77  ? 291.457 296.390 99.011  1.00 78.27  ? 77  TYR A CZ  1 
ATOM 477  O OH  . TYR A 1 77  ? 290.336 295.643 99.274  1.00 78.27  ? 77  TYR A OH  1 
ATOM 478  N N   . GLU A 1 78  ? 297.537 298.652 99.795  1.00 69.51  ? 78  GLU A N   1 
ATOM 479  C CA  . GLU A 1 78  ? 298.960 298.674 100.104 1.00 69.51  ? 78  GLU A CA  1 
ATOM 480  C C   . GLU A 1 78  ? 299.670 297.512 99.426  1.00 69.51  ? 78  GLU A C   1 
ATOM 481  O O   . GLU A 1 78  ? 299.083 296.454 99.185  1.00 69.51  ? 78  GLU A O   1 
ATOM 482  C CB  . GLU A 1 78  ? 299.209 298.618 101.623 1.00 69.51  ? 78  GLU A CB  1 
ATOM 483  C CG  . GLU A 1 78  ? 300.469 299.341 102.111 1.00 69.51  ? 78  GLU A CG  1 
ATOM 484  C CD  . GLU A 1 78  ? 300.422 300.857 101.955 1.00 69.51  ? 78  GLU A CD  1 
ATOM 485  O OE1 . GLU A 1 78  ? 299.325 301.417 101.760 1.00 69.51  ? 78  GLU A OE1 1 
ATOM 486  O OE2 . GLU A 1 78  ? 301.495 301.497 102.029 1.00 69.51  ? 78  GLU A OE2 1 
ATOM 487  N N   . ALA A 1 79  ? 300.950 297.724 99.124  1.00 66.22  ? 79  ALA A N   1 
ATOM 488  C CA  . ALA A 1 79  ? 301.794 296.687 98.555  1.00 66.22  ? 79  ALA A CA  1 
ATOM 489  C C   . ALA A 1 79  ? 303.188 296.773 99.154  1.00 66.22  ? 79  ALA A C   1 
ATOM 490  O O   . ALA A 1 79  ? 303.638 297.839 99.580  1.00 66.22  ? 79  ALA A O   1 
ATOM 491  C CB  . ALA A 1 79  ? 301.876 296.790 97.034  1.00 66.22  ? 79  ALA A CB  1 
ATOM 492  N N   . LYS A 1 80  ? 303.866 295.626 99.186  1.00 68.67  ? 80  LYS A N   1 
ATOM 493  C CA  . LYS A 1 80  ? 305.217 295.505 99.738  1.00 68.67  ? 80  LYS A CA  1 
ATOM 494  C C   . LYS A 1 80  ? 305.930 294.426 98.932  1.00 68.67  ? 80  LYS A C   1 
ATOM 495  O O   . LYS A 1 80  ? 305.844 293.238 99.254  1.00 68.67  ? 80  LYS A O   1 
ATOM 496  C CB  . LYS A 1 80  ? 305.174 295.161 101.218 1.00 68.67  ? 80  LYS A CB  1 
ATOM 497  C CG  . LYS A 1 80  ? 306.132 295.942 102.088 1.00 68.67  ? 80  LYS A CG  1 
ATOM 498  C CD  . LYS A 1 80  ? 305.829 295.664 103.548 1.00 68.67  ? 80  LYS A CD  1 
ATOM 499  C CE  . LYS A 1 80  ? 306.888 296.224 104.467 1.00 68.67  ? 80  LYS A CE  1 
ATOM 500  N NZ  . LYS A 1 80  ? 306.909 295.522 105.777 1.00 68.67  ? 80  LYS A NZ  1 
ATOM 501  N N   . VAL A 1 81  ? 306.650 294.845 97.897  1.00 71.24  ? 81  VAL A N   1 
ATOM 502  C CA  . VAL A 1 81  ? 307.355 293.928 97.013  1.00 71.24  ? 81  VAL A CA  1 
ATOM 503  C C   . VAL A 1 81  ? 308.843 294.219 97.152  1.00 71.24  ? 81  VAL A C   1 
ATOM 504  O O   . VAL A 1 81  ? 309.359 295.185 96.575  1.00 71.24  ? 81  VAL A O   1 
ATOM 505  C CB  . VAL A 1 81  ? 306.892 294.049 95.556  1.00 71.24  ? 81  VAL A CB  1 
ATOM 506  C CG1 . VAL A 1 81  ? 307.643 293.075 94.676  1.00 71.24  ? 81  VAL A CG1 1 
ATOM 507  C CG2 . VAL A 1 81  ? 305.395 293.819 95.443  1.00 71.24  ? 81  VAL A CG2 1 
ATOM 508  N N   . TRP A 1 82  ? 309.526 293.390 97.933  1.00 78.30  ? 82  TRP A N   1 
ATOM 509  C CA  . TRP A 1 82  ? 310.972 293.471 98.084  1.00 78.30  ? 82  TRP A CA  1 
ATOM 510  C C   . TRP A 1 82  ? 311.642 292.965 96.817  1.00 78.30  ? 82  TRP A C   1 
ATOM 511  O O   . TRP A 1 82  ? 311.444 291.811 96.428  1.00 78.30  ? 82  TRP A O   1 
ATOM 512  C CB  . TRP A 1 82  ? 311.412 292.645 99.286  1.00 78.30  ? 82  TRP A CB  1 
ATOM 513  C CG  . TRP A 1 82  ? 312.884 292.564 99.453  1.00 78.30  ? 82  TRP A CG  1 
ATOM 514  C CD1 . TRP A 1 82  ? 313.734 293.587 99.754  1.00 78.30  ? 82  TRP A CD1 1 
ATOM 515  C CD2 . TRP A 1 82  ? 313.691 291.393 99.326  1.00 78.30  ? 82  TRP A CD2 1 
ATOM 516  N NE1 . TRP A 1 82  ? 315.022 293.126 99.826  1.00 78.30  ? 82  TRP A NE1 1 
ATOM 517  C CE2 . TRP A 1 82  ? 315.026 291.780 99.566  1.00 78.30  ? 82  TRP A CE2 1 
ATOM 518  C CE3 . TRP A 1 82  ? 313.416 290.053 99.034  1.00 78.30  ? 82  TRP A CE3 1 
ATOM 519  C CZ2 . TRP A 1 82  ? 316.083 290.875 99.527  1.00 78.30  ? 82  TRP A CZ2 1 
ATOM 520  C CZ3 . TRP A 1 82  ? 314.469 289.156 98.993  1.00 78.30  ? 82  TRP A CZ3 1 
ATOM 521  C CH2 . TRP A 1 82  ? 315.786 289.570 99.236  1.00 78.30  ? 82  TRP A CH2 1 
ATOM 522  N N   . VAL A 1 83  ? 312.439 293.816 96.179  1.00 79.09  ? 83  VAL A N   1 
ATOM 523  C CA  . VAL A 1 83  ? 313.120 293.428 94.951  1.00 79.09  ? 83  VAL A CA  1 
ATOM 524  C C   . VAL A 1 83  ? 314.472 292.829 95.303  1.00 79.09  ? 83  VAL A C   1 
ATOM 525  O O   . VAL A 1 83  ? 314.917 292.906 96.450  1.00 79.09  ? 83  VAL A O   1 
ATOM 526  C CB  . VAL A 1 83  ? 313.294 294.615 93.989  1.00 79.09  ? 83  VAL A CB  1 
ATOM 527  C CG1 . VAL A 1 83  ? 311.953 295.277 93.693  1.00 79.09  ? 83  VAL A CG1 1 
ATOM 528  C CG2 . VAL A 1 83  ? 314.295 295.604 94.541  1.00 79.09  ? 83  VAL A CG2 1 
ATOM 529  N N   . GLY A 1 89  ? 318.911 296.974 86.738  1.00 79.30  ? 89  GLY A N   1 
ATOM 530  C CA  . GLY A 1 89  ? 319.303 295.629 86.358  1.00 79.30  ? 89  GLY A CA  1 
ATOM 531  C C   . GLY A 1 89  ? 319.582 294.723 87.541  1.00 79.30  ? 89  GLY A C   1 
ATOM 532  O O   . GLY A 1 89  ? 319.037 293.622 87.630  1.00 79.30  ? 89  GLY A O   1 
ATOM 533  N N   . LEU A 1 90  ? 320.440 295.188 88.453  1.00 84.66  ? 90  LEU A N   1 
ATOM 534  C CA  . LEU A 1 90  ? 320.777 294.402 89.636  1.00 84.66  ? 90  LEU A CA  1 
ATOM 535  C C   . LEU A 1 90  ? 319.634 294.358 90.640  1.00 84.66  ? 90  LEU A C   1 
ATOM 536  O O   . LEU A 1 90  ? 319.521 293.382 91.389  1.00 84.66  ? 90  LEU A O   1 
ATOM 537  C CB  . LEU A 1 90  ? 322.036 294.956 90.310  1.00 84.66  ? 90  LEU A CB  1 
ATOM 538  C CG  . LEU A 1 90  ? 323.424 294.468 89.867  1.00 84.66  ? 90  LEU A CG  1 
ATOM 539  C CD1 . LEU A 1 90  ? 323.566 292.971 90.113  1.00 84.66  ? 90  LEU A CD1 1 
ATOM 540  C CD2 . LEU A 1 90  ? 323.763 294.818 88.418  1.00 84.66  ? 90  LEU A CD2 1 
ATOM 541  N N   . ASN A 1 91  ? 318.792 295.390 90.675  1.00 86.38  ? 91  ASN A N   1 
ATOM 542  C CA  . ASN A 1 91  ? 317.590 295.348 91.494  1.00 86.38  ? 91  ASN A CA  1 
ATOM 543  C C   . ASN A 1 91  ? 316.445 294.628 90.799  1.00 86.38  ? 91  ASN A C   1 
ATOM 544  O O   . ASN A 1 91  ? 315.467 294.261 91.459  1.00 86.38  ? 91  ASN A O   1 
ATOM 545  C CB  . ASN A 1 91  ? 317.156 296.767 91.868  1.00 86.38  ? 91  ASN A CB  1 
ATOM 546  C CG  . ASN A 1 91  ? 317.673 297.195 93.226  1.00 86.38  ? 91  ASN A CG  1 
ATOM 547  O OD1 . ASN A 1 91  ? 317.483 296.500 94.224  1.00 86.38  ? 91  ASN A OD1 1 
ATOM 548  N ND2 . ASN A 1 91  ? 318.333 298.346 93.270  1.00 86.38  ? 91  ASN A ND2 1 
ATOM 549  N N   . LYS A 1 92  ? 316.546 294.414 89.487  1.00 88.61  ? 92  LYS A N   1 
ATOM 550  C CA  . LYS A 1 92  ? 315.492 293.747 88.737  1.00 88.61  ? 92  LYS A CA  1 
ATOM 551  C C   . LYS A 1 92  ? 315.778 292.272 88.495  1.00 88.61  ? 92  LYS A C   1 
ATOM 552  O O   . LYS A 1 92  ? 314.847 291.518 88.191  1.00 88.61  ? 92  LYS A O   1 
ATOM 553  C CB  . LYS A 1 92  ? 315.256 294.457 87.395  1.00 88.61  ? 92  LYS A CB  1 
ATOM 554  C CG  . LYS A 1 92  ? 315.088 295.978 87.499  1.00 88.61  ? 92  LYS A CG  1 
ATOM 555  C CD  . LYS A 1 92  ? 314.064 296.368 88.565  1.00 88.61  ? 92  LYS A CD  1 
ATOM 556  C CE  . LYS A 1 92  ? 313.559 297.786 88.392  1.00 88.61  ? 92  LYS A CE  1 
ATOM 557  N NZ  . LYS A 1 92  ? 312.481 298.068 89.378  1.00 88.61  ? 92  LYS A NZ  1 
ATOM 558  N N   . TYR A 1 93  ? 317.033 291.845 88.621  1.00 92.10  ? 93  TYR A N   1 
ATOM 559  C CA  . TYR A 1 93  ? 317.361 290.424 88.684  1.00 92.10  ? 93  TYR A CA  1 
ATOM 560  C C   . TYR A 1 93  ? 317.426 290.020 90.158  1.00 92.10  ? 93  TYR A C   1 
ATOM 561  O O   . TYR A 1 93  ? 318.485 289.886 90.772  1.00 92.10  ? 93  TYR A O   1 
ATOM 562  C CB  . TYR A 1 93  ? 318.657 290.139 87.921  1.00 92.10  ? 93  TYR A CB  1 
ATOM 563  C CG  . TYR A 1 93  ? 319.123 288.693 87.941  1.00 92.10  ? 93  TYR A CG  1 
ATOM 564  C CD1 . TYR A 1 93  ? 318.543 287.750 87.101  1.00 92.10  ? 93  TYR A CD1 1 
ATOM 565  C CD2 . TYR A 1 93  ? 320.194 288.288 88.738  1.00 92.10  ? 93  TYR A CD2 1 
ATOM 566  C CE1 . TYR A 1 93  ? 318.973 286.432 87.100  1.00 92.10  ? 93  TYR A CE1 1 
ATOM 567  C CE2 . TYR A 1 93  ? 320.628 286.975 88.745  1.00 92.10  ? 93  TYR A CE2 1 
ATOM 568  C CZ  . TYR A 1 93  ? 320.017 286.053 87.921  1.00 92.10  ? 93  TYR A CZ  1 
ATOM 569  O OH  . TYR A 1 93  ? 320.451 284.747 87.919  1.00 92.10  ? 93  TYR A OH  1 
ATOM 570  N N   . ASN A 1 94  ? 316.234 289.891 90.735  1.00 88.06  ? 94  ASN A N   1 
ATOM 571  C CA  . ASN A 1 94  ? 316.074 289.554 92.141  1.00 88.06  ? 94  ASN A CA  1 
ATOM 572  C C   . ASN A 1 94  ? 314.672 288.994 92.329  1.00 88.06  ? 94  ASN A C   1 
ATOM 573  O O   . ASN A 1 94  ? 313.790 289.188 91.489  1.00 88.06  ? 94  ASN A O   1 
ATOM 574  C CB  . ASN A 1 94  ? 316.306 290.778 93.042  1.00 88.06  ? 94  ASN A CB  1 
ATOM 575  C CG  . ASN A 1 94  ? 316.638 290.404 94.478  1.00 88.06  ? 94  ASN A CG  1 
ATOM 576  O OD1 . ASN A 1 94  ? 315.914 289.645 95.122  1.00 88.06  ? 94  ASN A OD1 1 
ATOM 577  N ND2 . ASN A 1 94  ? 317.734 290.951 94.990  1.00 88.06  ? 94  ASN A ND2 1 
ATOM 578  N N   . PHE A 1 95  ? 314.475 288.287 93.440  1.00 86.45  ? 95  PHE A N   1 
ATOM 579  C CA  . PHE A 1 95  ? 313.167 287.724 93.761  1.00 86.45  ? 95  PHE A CA  1 
ATOM 580  C C   . PHE A 1 95  ? 312.253 288.839 94.252  1.00 86.45  ? 95  PHE A C   1 
ATOM 581  O O   . PHE A 1 95  ? 312.435 289.357 95.357  1.00 86.45  ? 95  PHE A O   1 
ATOM 582  C CB  . PHE A 1 95  ? 313.293 286.621 94.808  1.00 86.45  ? 95  PHE A CB  1 
ATOM 583  C CG  . PHE A 1 95  ? 311.983 285.972 95.167  1.00 86.45  ? 95  PHE A CG  1 
ATOM 584  C CD1 . PHE A 1 95  ? 311.086 285.590 94.177  1.00 86.45  ? 95  PHE A CD1 1 
ATOM 585  C CD2 . PHE A 1 95  ? 311.648 285.742 96.494  1.00 86.45  ? 95  PHE A CD2 1 
ATOM 586  C CE1 . PHE A 1 95  ? 309.878 284.994 94.506  1.00 86.45  ? 95  PHE A CE1 1 
ATOM 587  C CE2 . PHE A 1 95  ? 310.441 285.144 96.829  1.00 86.45  ? 95  PHE A CE2 1 
ATOM 588  C CZ  . PHE A 1 95  ? 309.557 284.770 95.835  1.00 86.45  ? 95  PHE A CZ  1 
ATOM 589  N N   . LYS A 1 96  ? 311.270 289.205 93.433  1.00 83.50  ? 96  LYS A N   1 
ATOM 590  C CA  . LYS A 1 96  ? 310.269 290.198 93.804  1.00 83.50  ? 96  LYS A CA  1 
ATOM 591  C C   . LYS A 1 96  ? 309.164 289.508 94.598  1.00 83.50  ? 96  LYS A C   1 
ATOM 592  O O   . LYS A 1 96  ? 308.397 288.715 94.040  1.00 83.50  ? 96  LYS A O   1 
ATOM 593  C CB  . LYS A 1 96  ? 309.708 290.881 92.557  1.00 83.50  ? 96  LYS A CB  1 
ATOM 594  C CG  . LYS A 1 96  ? 310.367 292.216 92.226  1.00 83.50  ? 96  LYS A CG  1 
ATOM 595  C CD  . LYS A 1 96  ? 310.505 292.414 90.721  1.00 83.50  ? 96  LYS A CD  1 
ATOM 596  C CE  . LYS A 1 96  ? 311.166 293.744 90.388  1.00 83.50  ? 96  LYS A CE  1 
ATOM 597  N NZ  . LYS A 1 96  ? 311.675 293.781 88.991  1.00 83.50  ? 96  LYS A NZ  1 
ATOM 598  N N   . GLU A 1 97  ? 309.081 289.809 95.894  1.00 77.99  ? 97  GLU A N   1 
ATOM 599  C CA  . GLU A 1 97  ? 308.245 289.058 96.825  1.00 77.99  ? 97  GLU A CA  1 
ATOM 600  C C   . GLU A 1 97  ? 307.202 289.968 97.462  1.00 77.99  ? 97  GLU A C   1 
ATOM 601  O O   . GLU A 1 97  ? 307.548 290.858 98.245  1.00 77.99  ? 97  GLU A O   1 
ATOM 602  C CB  . GLU A 1 97  ? 309.102 288.399 97.907  1.00 77.99  ? 97  GLU A CB  1 
ATOM 603  C CG  . GLU A 1 97  ? 308.304 287.622 98.940  1.00 77.99  ? 97  GLU A CG  1 
ATOM 604  C CD  . GLU A 1 97  ? 309.169 287.066 100.052 1.00 77.99  ? 97  GLU A CD  1 
ATOM 605  O OE1 . GLU A 1 97  ? 310.400 287.266 100.006 1.00 77.99  ? 97  GLU A OE1 1 
ATOM 606  O OE2 . GLU A 1 97  ? 308.616 286.430 100.972 1.00 77.99  ? 97  GLU A OE2 1 
ATOM 607  N N   . LEU A 1 98  ? 305.929 289.719 97.151  1.00 72.69  ? 98  LEU A N   1 
ATOM 608  C CA  . LEU A 1 98  ? 304.819 290.430 97.771  1.00 72.69  ? 98  LEU A CA  1 
ATOM 609  C C   . LEU A 1 98  ? 304.384 289.701 99.036  1.00 72.69  ? 98  LEU A C   1 
ATOM 610  O O   . LEU A 1 98  ? 304.382 288.468 99.082  1.00 72.69  ? 98  LEU A O   1 
ATOM 611  C CB  . LEU A 1 98  ? 303.636 290.548 96.804  1.00 72.69  ? 98  LEU A CB  1 
ATOM 612  C CG  . LEU A 1 98  ? 302.407 291.344 97.268  1.00 72.69  ? 98  LEU A CG  1 
ATOM 613  C CD1 . LEU A 1 98  ? 302.797 292.688 97.861  1.00 72.69  ? 98  LEU A CD1 1 
ATOM 614  C CD2 . LEU A 1 98  ? 301.394 291.527 96.161  1.00 72.69  ? 98  LEU A CD2 1 
ATOM 615  N N   . GLN A 1 99  ? 304.028 290.468 100.069 1.00 76.50  ? 99  GLN A N   1 
ATOM 616  C CA  . GLN A 1 99  ? 303.566 289.895 101.325 1.00 76.50  ? 99  GLN A CA  1 
ATOM 617  C C   . GLN A 1 99  ? 302.156 290.305 101.732 1.00 76.50  ? 99  GLN A C   1 
ATOM 618  O O   . GLN A 1 99  ? 301.521 289.572 102.491 1.00 76.50  ? 99  GLN A O   1 
ATOM 619  C CB  . GLN A 1 99  ? 304.537 290.244 102.465 1.00 76.50  ? 99  GLN A CB  1 
ATOM 620  C CG  . GLN A 1 99  ? 304.501 291.686 102.935 1.00 76.50  ? 99  GLN A CG  1 
ATOM 621  C CD  . GLN A 1 99  ? 304.820 291.818 104.408 1.00 76.50  ? 99  GLN A CD  1 
ATOM 622  O OE1 . GLN A 1 99  ? 305.435 290.934 105.001 1.00 76.50  ? 99  GLN A OE1 1 
ATOM 623  N NE2 . GLN A 1 99  ? 304.387 292.919 105.012 1.00 76.50  ? 99  GLN A NE2 1 
ATOM 624  N N   . GLU A 1 100 ? 301.636 291.439 101.258 1.00 71.91  ? 100 GLU A N   1 
ATOM 625  C CA  . GLU A 1 100 ? 300.332 291.889 101.731 1.00 71.91  ? 100 GLU A CA  1 
ATOM 626  C C   . GLU A 1 100 ? 299.579 292.655 100.654 1.00 71.91  ? 100 GLU A C   1 
ATOM 627  O O   . GLU A 1 100 ? 300.174 293.270 99.765  1.00 71.91  ? 100 GLU A O   1 
ATOM 628  C CB  . GLU A 1 100 ? 300.450 292.763 102.993 1.00 71.91  ? 100 GLU A CB  1 
ATOM 629  C CG  . GLU A 1 100 ? 301.534 293.860 102.979 1.00 71.91  ? 100 GLU A CG  1 
ATOM 630  C CD  . GLU A 1 100 ? 301.155 295.135 102.235 1.00 71.91  ? 100 GLU A CD  1 
ATOM 631  O OE1 . GLU A 1 100 ? 299.960 295.364 101.968 1.00 71.91  ? 100 GLU A OE1 1 
ATOM 632  O OE2 . GLU A 1 100 ? 302.065 295.937 101.945 1.00 71.91  ? 100 GLU A OE2 1 
ATOM 633  N N   . PHE A 1 101 ? 298.256 292.633 100.773 1.00 74.22  ? 101 PHE A N   1 
ATOM 634  C CA  . PHE A 1 101 ? 297.351 293.540 100.078 1.00 74.22  ? 101 PHE A CA  1 
ATOM 635  C C   . PHE A 1 101 ? 296.328 294.088 101.062 1.00 74.22  ? 101 PHE A C   1 
ATOM 636  O O   . PHE A 1 101 ? 295.116 294.036 100.838 1.00 74.22  ? 101 PHE A O   1 
ATOM 637  C CB  . PHE A 1 101 ? 296.663 292.871 98.896  1.00 74.22  ? 101 PHE A CB  1 
ATOM 638  C CG  . PHE A 1 101 ? 296.357 293.817 97.772  1.00 74.22  ? 101 PHE A CG  1 
ATOM 639  C CD1 . PHE A 1 101 ? 297.359 294.231 96.908  1.00 74.22  ? 101 PHE A CD1 1 
ATOM 640  C CD2 . PHE A 1 101 ? 295.076 294.306 97.588  1.00 74.22  ? 101 PHE A CD2 1 
ATOM 641  C CE1 . PHE A 1 101 ? 297.084 295.108 95.873  1.00 74.22  ? 101 PHE A CE1 1 
ATOM 642  C CE2 . PHE A 1 101 ? 294.795 295.179 96.553  1.00 74.22  ? 101 PHE A CE2 1 
ATOM 643  C CZ  . PHE A 1 101 ? 295.799 295.583 95.698  1.00 74.22  ? 101 PHE A CZ  1 
ATOM 644  N N   . LYS A 1 102 ? 296.829 294.603 102.186 1.00 70.79  ? 102 LYS A N   1 
ATOM 645  C CA  . LYS A 1 102 ? 295.984 295.011 103.297 1.00 70.79  ? 102 LYS A CA  1 
ATOM 646  C C   . LYS A 1 102 ? 295.173 296.263 102.953 1.00 70.79  ? 102 LYS A C   1 
ATOM 647  O O   . LYS A 1 102 ? 295.633 297.131 102.204 1.00 70.79  ? 102 LYS A O   1 
ATOM 648  C CB  . LYS A 1 102 ? 296.834 295.272 104.542 1.00 70.79  ? 102 LYS A CB  1 
ATOM 649  C CG  . LYS A 1 102 ? 297.929 296.318 104.365 1.00 70.79  ? 102 LYS A CG  1 
ATOM 650  C CD  . LYS A 1 102 ? 299.198 295.977 105.140 1.00 70.79  ? 102 LYS A CD  1 
ATOM 651  C CE  . LYS A 1 102 ? 299.025 296.172 106.639 1.00 70.79  ? 102 LYS A CE  1 
ATOM 652  N NZ  . LYS A 1 102 ? 300.311 296.016 107.377 1.00 70.79  ? 102 LYS A NZ  1 
ATOM 653  N N   . PRO A 1 103 ? 293.947 296.362 103.463 1.00 69.08  ? 103 PRO A N   1 
ATOM 654  C CA  . PRO A 1 103 ? 293.191 297.608 103.331 1.00 69.08  ? 103 PRO A CA  1 
ATOM 655  C C   . PRO A 1 103 ? 293.580 298.604 104.407 1.00 69.08  ? 103 PRO A C   1 
ATOM 656  O O   . PRO A 1 103 ? 294.102 298.245 105.464 1.00 69.08  ? 103 PRO A O   1 
ATOM 657  C CB  . PRO A 1 103 ? 291.736 297.157 103.500 1.00 69.08  ? 103 PRO A CB  1 
ATOM 658  C CG  . PRO A 1 103 ? 291.825 295.955 104.364 1.00 69.08  ? 103 PRO A CG  1 
ATOM 659  C CD  . PRO A 1 103 ? 293.134 295.280 104.047 1.00 69.08  ? 103 PRO A CD  1 
ATOM 660  N N   . VAL A 1 104 ? 293.325 299.874 104.120 1.00 69.30  ? 104 VAL A N   1 
ATOM 661  C CA  . VAL A 1 104 ? 293.607 300.960 105.049 1.00 69.30  ? 104 VAL A CA  1 
ATOM 662  C C   . VAL A 1 104 ? 292.258 301.473 105.536 1.00 69.30  ? 104 VAL A C   1 
ATOM 663  O O   . VAL A 1 104 ? 291.617 302.307 104.886 1.00 69.30  ? 104 VAL A O   1 
ATOM 664  C CB  . VAL A 1 104 ? 294.447 302.067 104.403 1.00 69.30  ? 104 VAL A CB  1 
ATOM 665  C CG1 . VAL A 1 104 ? 294.758 303.168 105.414 1.00 69.30  ? 104 VAL A CG1 1 
ATOM 666  C CG2 . VAL A 1 104 ? 295.724 301.481 103.824 1.00 69.30  ? 104 VAL A CG2 1 
ATOM 667  N N   . GLY A 1 105 ? 291.821 300.966 106.685 1.00 63.98  ? 105 GLY A N   1 
ATOM 668  C CA  . GLY A 1 105 ? 290.499 301.253 107.200 1.00 63.98  ? 105 GLY A CA  1 
ATOM 669  C C   . GLY A 1 105 ? 289.707 299.985 107.442 1.00 63.98  ? 105 GLY A C   1 
ATOM 670  O O   . GLY A 1 105 ? 289.493 299.191 106.521 1.00 63.98  ? 105 GLY A O   1 
ATOM 671  N N   . ASP A 1 106 ? 289.268 299.783 108.683 1.00 59.97  ? 106 ASP A N   1 
ATOM 672  C CA  . ASP A 1 106 ? 288.571 298.571 109.086 1.00 59.97  ? 106 ASP A CA  1 
ATOM 673  C C   . ASP A 1 106 ? 287.055 298.691 108.929 1.00 59.97  ? 106 ASP A C   1 
ATOM 674  O O   . ASP A 1 106 ? 286.308 297.958 109.586 1.00 59.97  ? 106 ASP A O   1 
ATOM 675  C CB  . ASP A 1 106 ? 288.944 298.225 110.530 1.00 59.97  ? 106 ASP A CB  1 
ATOM 676  C CG  . ASP A 1 106 ? 288.862 296.749 110.824 1.00 59.97  ? 106 ASP A CG  1 
ATOM 677  O OD1 . ASP A 1 106 ? 289.710 295.998 110.312 1.00 59.97  ? 106 ASP A OD1 1 
ATOM 678  O OD2 . ASP A 1 106 ? 287.967 296.340 111.589 1.00 59.97  ? 106 ASP A OD2 1 
ATOM 679  N N   . ALA A 1 107 ? 286.586 299.593 108.069 1.00 66.91  ? 107 ALA A N   1 
ATOM 680  C CA  . ALA A 1 107 ? 285.153 299.805 107.862 1.00 66.91  ? 107 ALA A CA  1 
ATOM 681  C C   . ALA A 1 107 ? 284.613 298.946 106.723 1.00 66.91  ? 107 ALA A C   1 
ATOM 682  O O   . ALA A 1 107 ? 283.955 299.430 105.804 1.00 66.91  ? 107 ALA A O   1 
ATOM 683  C CB  . ALA A 1 107 ? 284.873 301.282 107.611 1.00 66.91  ? 107 ALA A CB  1 
ATOM 684  N N   . GLY A 1 108 ? 284.885 297.648 106.789 1.00 66.13  ? 108 GLY A N   1 
ATOM 685  C CA  . GLY A 1 108 ? 284.303 296.710 105.854 1.00 66.13  ? 108 GLY A CA  1 
ATOM 686  C C   . GLY A 1 108 ? 283.065 296.041 106.416 1.00 66.13  ? 108 GLY A C   1 
ATOM 687  O O   . GLY A 1 108 ? 282.706 294.937 106.000 1.00 66.13  ? 108 GLY A O   1 
ATOM 688  N N   . GLY A 1 109 ? 282.406 296.706 107.364 1.00 64.45  ? 109 GLY A N   1 
ATOM 689  C CA  . GLY A 1 109 ? 281.217 296.160 107.984 1.00 64.45  ? 109 GLY A CA  1 
ATOM 690  C C   . GLY A 1 109 ? 281.479 294.967 108.868 1.00 64.45  ? 109 GLY A C   1 
ATOM 691  O O   . GLY A 1 109 ? 280.602 294.108 109.014 1.00 64.45  ? 109 GLY A O   1 
ATOM 692  N N   . ARG A 1 110 ? 282.669 294.890 109.470 1.00 64.30  ? 110 ARG A N   1 
ATOM 693  C CA  . ARG A 1 110 ? 283.061 293.713 110.236 1.00 64.30  ? 110 ARG A CA  1 
ATOM 694  C C   . ARG A 1 110 ? 282.332 293.613 111.562 1.00 64.30  ? 110 ARG A C   1 
ATOM 695  O O   . ARG A 1 110 ? 282.277 292.524 112.142 1.00 64.30  ? 110 ARG A O   1 
ATOM 696  C CB  . ARG A 1 110 ? 284.569 293.715 110.499 1.00 64.30  ? 110 ARG A CB  1 
ATOM 697  C CG  . ARG A 1 110 ? 285.413 293.383 109.288 1.00 64.30  ? 110 ARG A CG  1 
ATOM 698  C CD  . ARG A 1 110 ? 285.885 294.634 108.579 1.00 64.30  ? 110 ARG A CD  1 
ATOM 699  N NE  . ARG A 1 110 ? 286.500 294.320 107.297 1.00 64.30  ? 110 ARG A NE  1 
ATOM 700  C CZ  . ARG A 1 110 ? 287.766 293.953 107.135 1.00 64.30  ? 110 ARG A CZ  1 
ATOM 701  N NH1 . ARG A 1 110 ? 288.573 293.845 108.182 1.00 64.30  ? 110 ARG A NH1 1 
ATOM 702  N NH2 . ARG A 1 110 ? 288.225 293.691 105.920 1.00 64.30  ? 110 ARG A NH2 1 
ATOM 703  N N   . MET A 1 111 ? 281.786 294.720 112.052 1.00 32.16  ? 111 MET A N   1 
ATOM 704  C CA  . MET A 1 111 ? 281.031 294.743 113.290 1.00 32.16  ? 111 MET A CA  1 
ATOM 705  C C   . MET A 1 111 ? 279.881 295.716 113.120 1.00 32.16  ? 111 MET A C   1 
ATOM 706  O O   . MET A 1 111 ? 280.074 296.834 112.637 1.00 32.16  ? 111 MET A O   1 
ATOM 707  C CB  . MET A 1 111 ? 281.912 295.144 114.468 1.00 32.16  ? 111 MET A CB  1 
ATOM 708  C CG  . MET A 1 111 ? 281.247 294.997 115.801 1.00 32.16  ? 111 MET A CG  1 
ATOM 709  S SD  . MET A 1 111 ? 282.378 295.006 117.193 1.00 32.16  ? 111 MET A SD  1 
ATOM 710  C CE  . MET A 1 111 ? 283.656 296.071 116.565 1.00 32.16  ? 111 MET A CE  1 
ATOM 711  N N   . ASP A 1 112 ? 278.685 295.280 113.503 1.00 29.68  ? 112 ASP A N   1 
ATOM 712  C CA  . ASP A 1 112 ? 277.452 296.035 113.290 1.00 29.68  ? 112 ASP A CA  1 
ATOM 713  C C   . ASP A 1 112 ? 276.982 296.578 114.633 1.00 29.68  ? 112 ASP A C   1 
ATOM 714  O O   . ASP A 1 112 ? 276.162 295.965 115.315 1.00 29.68  ? 112 ASP A O   1 
ATOM 715  C CB  . ASP A 1 112 ? 276.393 295.163 112.653 1.00 29.68  ? 112 ASP A CB  1 
ATOM 716  C CG  . ASP A 1 112 ? 275.557 295.912 111.652 1.00 29.68  ? 112 ASP A CG  1 
ATOM 717  O OD1 . ASP A 1 112 ? 274.712 295.273 110.991 1.00 29.68  ? 112 ASP A OD1 1 
ATOM 718  O OD2 . ASP A 1 112 ? 275.747 297.139 111.522 1.00 29.68  ? 112 ASP A OD2 1 
ATOM 719  N N   . ILE A 1 113 ? 277.500 297.730 115.002 1.00 23.22  ? 113 ILE A N   1 
ATOM 720  C CA  . ILE A 1 113 ? 277.119 298.390 116.239 1.00 23.22  ? 113 ILE A CA  1 
ATOM 721  C C   . ILE A 1 113 ? 275.917 299.267 115.951 1.00 23.22  ? 113 ILE A C   1 
ATOM 722  O O   . ILE A 1 113 ? 275.868 299.964 114.934 1.00 23.22  ? 113 ILE A O   1 
ATOM 723  C CB  . ILE A 1 113 ? 278.286 299.216 116.812 1.00 23.22  ? 113 ILE A CB  1 
ATOM 724  C CG1 . ILE A 1 113 ? 279.544 298.368 116.943 1.00 23.22  ? 113 ILE A CG1 1 
ATOM 725  C CG2 . ILE A 1 113 ? 277.932 299.755 118.178 1.00 23.22  ? 113 ILE A CG2 1 
ATOM 726  C CD1 . ILE A 1 113 ? 279.453 297.334 118.018 1.00 23.22  ? 113 ILE A CD1 1 
ATOM 727  N N   . ASP A 1 114 ? 274.933 299.222 116.834 1.00 21.85  ? 114 ASP A N   1 
ATOM 728  C CA  . ASP A 1 114 ? 273.844 300.170 116.794 1.00 21.85  ? 114 ASP A CA  1 
ATOM 729  C C   . ASP A 1 114 ? 274.005 301.128 117.961 1.00 21.85  ? 114 ASP A C   1 
ATOM 730  O O   . ASP A 1 114 ? 274.083 300.673 119.111 1.00 21.85  ? 114 ASP A O   1 
ATOM 731  C CB  . ASP A 1 114 ? 272.515 299.447 116.875 1.00 21.85  ? 114 ASP A CB  1 
ATOM 732  C CG  . ASP A 1 114 ? 271.431 300.165 116.148 1.00 21.85  ? 114 ASP A CG  1 
ATOM 733  O OD1 . ASP A 1 114 ? 271.536 300.285 114.916 1.00 21.85  ? 114 ASP A OD1 1 
ATOM 734  O OD2 . ASP A 1 114 ? 270.469 300.588 116.803 1.00 21.85  ? 114 ASP A OD2 1 
ATOM 735  N N   . PRO A 1 115 ? 274.089 302.441 117.729 1.00 15.94  ? 115 PRO A N   1 
ATOM 736  C CA  . PRO A 1 115 ? 274.341 303.365 118.837 1.00 15.94  ? 115 PRO A CA  1 
ATOM 737  C C   . PRO A 1 115 ? 273.166 303.537 119.772 1.00 15.94  ? 115 PRO A C   1 
ATOM 738  O O   . PRO A 1 115 ? 273.352 304.078 120.870 1.00 15.94  ? 115 PRO A O   1 
ATOM 739  C CB  . PRO A 1 115 ? 274.666 304.673 118.123 1.00 15.94  ? 115 PRO A CB  1 
ATOM 740  C CG  . PRO A 1 115 ? 274.008 304.558 116.831 1.00 15.94  ? 115 PRO A CG  1 
ATOM 741  C CD  . PRO A 1 115 ? 274.079 303.136 116.437 1.00 15.94  ? 115 PRO A CD  1 
ATOM 742  N N   . TYR A 1 116 ? 271.968 303.103 119.385 1.00 13.98  ? 116 TYR A N   1 
ATOM 743  C CA  . TYR A 1 116 ? 270.789 303.265 120.211 1.00 13.98  ? 116 TYR A CA  1 
ATOM 744  C C   . TYR A 1 116 ? 270.306 301.974 120.837 1.00 13.98  ? 116 TYR A C   1 
ATOM 745  O O   . TYR A 1 116 ? 269.428 302.028 121.698 1.00 13.98  ? 116 TYR A O   1 
ATOM 746  C CB  . TYR A 1 116 ? 269.647 303.860 119.390 1.00 13.98  ? 116 TYR A CB  1 
ATOM 747  C CG  . TYR A 1 116 ? 270.046 304.992 118.504 1.00 13.98  ? 116 TYR A CG  1 
ATOM 748  C CD1 . TYR A 1 116 ? 270.301 306.245 119.017 1.00 13.98  ? 116 TYR A CD1 1 
ATOM 749  C CD2 . TYR A 1 116 ? 270.160 304.810 117.154 1.00 13.98  ? 116 TYR A CD2 1 
ATOM 750  C CE1 . TYR A 1 116 ? 270.656 307.275 118.201 1.00 13.98  ? 116 TYR A CE1 1 
ATOM 751  C CE2 . TYR A 1 116 ? 270.507 305.834 116.336 1.00 13.98  ? 116 TYR A CE2 1 
ATOM 752  C CZ  . TYR A 1 116 ? 270.757 307.057 116.859 1.00 13.98  ? 116 TYR A CZ  1 
ATOM 753  O OH  . TYR A 1 116 ? 271.119 308.059 116.002 1.00 13.98  ? 116 TYR A OH  1 
ATOM 754  N N   . LYS A 1 117 ? 270.853 300.829 120.433 1.00 13.20  ? 117 LYS A N   1 
ATOM 755  C CA  . LYS A 1 117 ? 270.301 299.535 120.814 1.00 13.20  ? 117 LYS A CA  1 
ATOM 756  C C   . LYS A 1 117 ? 270.445 299.264 122.300 1.00 13.20  ? 117 LYS A C   1 
ATOM 757  O O   . LYS A 1 117 ? 269.571 298.630 122.897 1.00 13.20  ? 117 LYS A O   1 
ATOM 758  C CB  . LYS A 1 117 ? 270.975 298.442 119.996 1.00 13.20  ? 117 LYS A CB  1 
ATOM 759  C CG  . LYS A 1 117 ? 270.485 297.039 120.234 1.00 13.20  ? 117 LYS A CG  1 
ATOM 760  C CD  . LYS A 1 117 ? 271.480 296.036 119.705 1.00 13.20  ? 117 LYS A CD  1 
ATOM 761  C CE  . LYS A 1 117 ? 270.820 294.709 119.442 1.00 13.20  ? 117 LYS A CE  1 
ATOM 762  N NZ  . LYS A 1 117 ? 269.670 294.499 120.343 1.00 13.20  ? 117 LYS A NZ  1 
ATOM 763  N N   . GLU A 1 118 ? 271.504 299.768 122.926 1.00 13.02  ? 118 GLU A N   1 
ATOM 764  C CA  . GLU A 1 118 ? 271.648 299.663 124.371 1.00 13.02  ? 118 GLU A CA  1 
ATOM 765  C C   . GLU A 1 118 ? 270.661 300.529 125.136 1.00 13.02  ? 118 GLU A C   1 
ATOM 766  O O   . GLU A 1 118 ? 270.503 300.330 126.342 1.00 13.02  ? 118 GLU A O   1 
ATOM 767  C CB  . GLU A 1 118 ? 273.063 300.040 124.772 1.00 13.02  ? 118 GLU A CB  1 
ATOM 768  C CG  . GLU A 1 118 ? 273.605 301.205 123.995 1.00 13.02  ? 118 GLU A CG  1 
ATOM 769  C CD  . GLU A 1 118 ? 274.892 301.744 124.561 1.00 13.02  ? 118 GLU A CD  1 
ATOM 770  O OE1 . GLU A 1 118 ? 275.254 301.365 125.693 1.00 13.02  ? 118 GLU A OE1 1 
ATOM 771  O OE2 . GLU A 1 118 ? 275.546 302.545 123.866 1.00 13.02  ? 118 GLU A OE2 1 
ATOM 772  N N   . PHE A 1 119 ? 269.996 301.468 124.467 1.00 16.36  ? 119 PHE A N   1 
ATOM 773  C CA  . PHE A 1 119 ? 269.089 302.412 125.095 1.00 16.36  ? 119 PHE A CA  1 
ATOM 774  C C   . PHE A 1 119 ? 267.633 302.131 124.776 1.00 16.36  ? 119 PHE A C   1 
ATOM 775  O O   . PHE A 1 119 ? 266.775 302.950 125.098 1.00 16.36  ? 119 PHE A O   1 
ATOM 776  C CB  . PHE A 1 119 ? 269.456 303.829 124.672 1.00 16.36  ? 119 PHE A CB  1 
ATOM 777  C CG  . PHE A 1 119 ? 270.852 304.207 125.033 1.00 16.36  ? 119 PHE A CG  1 
ATOM 778  C CD1 . PHE A 1 119 ? 271.231 304.287 126.352 1.00 16.36  ? 119 PHE A CD1 1 
ATOM 779  C CD2 . PHE A 1 119 ? 271.787 304.454 124.057 1.00 16.36  ? 119 PHE A CD2 1 
ATOM 780  C CE1 . PHE A 1 119 ? 272.497 304.602 126.683 1.00 16.36  ? 119 PHE A CE1 1 
ATOM 781  C CE2 . PHE A 1 119 ? 273.058 304.772 124.394 1.00 16.36  ? 119 PHE A CE2 1 
ATOM 782  C CZ  . PHE A 1 119 ? 273.409 304.854 125.708 1.00 16.36  ? 119 PHE A CZ  1 
ATOM 783  N N   . GLY A 1 120 ? 267.330 301.010 124.141 1.00 8.59   ? 120 GLY A N   1 
ATOM 784  C CA  . GLY A 1 120 ? 265.974 300.621 123.861 1.00 8.59   ? 120 GLY A CA  1 
ATOM 785  C C   . GLY A 1 120 ? 265.503 300.913 122.455 1.00 8.59   ? 120 GLY A C   1 
ATOM 786  O O   . GLY A 1 120 ? 264.477 300.371 122.044 1.00 8.59   ? 120 GLY A O   1 
ATOM 787  N N   . ALA A 1 121 ? 266.211 301.747 121.715 1.00 8.76   ? 121 ALA A N   1 
ATOM 788  C CA  . ALA A 1 121 ? 265.791 302.155 120.390 1.00 8.76   ? 121 ALA A CA  1 
ATOM 789  C C   . ALA A 1 121 ? 266.524 301.355 119.329 1.00 8.76   ? 121 ALA A C   1 
ATOM 790  O O   . ALA A 1 121 ? 267.157 300.340 119.616 1.00 8.76   ? 121 ALA A O   1 
ATOM 791  C CB  . ALA A 1 121 ? 266.021 303.647 120.208 1.00 8.76   ? 121 ALA A CB  1 
ATOM 792  N N   . THR A 1 122 ? 266.411 301.804 118.084 1.00 12.69  ? 122 THR A N   1 
ATOM 793  C CA  . THR A 1 122 ? 267.218 301.343 116.962 1.00 12.69  ? 122 THR A CA  1 
ATOM 794  C C   . THR A 1 122 ? 267.168 302.418 115.889 1.00 12.69  ? 122 THR A C   1 
ATOM 795  O O   . THR A 1 122 ? 266.424 303.389 116.005 1.00 12.69  ? 122 THR A O   1 
ATOM 796  C CB  . THR A 1 122 ? 266.724 299.999 116.433 1.00 12.69  ? 122 THR A CB  1 
ATOM 797  O OG1 . THR A 1 122 ? 267.499 299.615 115.295 1.00 12.69  ? 122 THR A OG1 1 
ATOM 798  C CG2 . THR A 1 122 ? 265.272 300.062 116.069 1.00 12.69  ? 122 THR A CG2 1 
ATOM 799  N N   . VAL A 1 123 ? 267.958 302.246 114.831 1.00 12.14  ? 123 VAL A N   1 
ATOM 800  C CA  . VAL A 1 123 ? 267.913 303.205 113.729 1.00 12.14  ? 123 VAL A CA  1 
ATOM 801  C C   . VAL A 1 123 ? 266.719 302.947 112.828 1.00 12.14  ? 123 VAL A C   1 
ATOM 802  O O   . VAL A 1 123 ? 266.325 303.828 112.052 1.00 12.14  ? 123 VAL A O   1 
ATOM 803  C CB  . VAL A 1 123 ? 269.249 303.174 112.966 1.00 12.14  ? 123 VAL A CB  1 
ATOM 804  C CG1 . VAL A 1 123 ? 269.427 304.384 112.053 1.00 12.14  ? 123 VAL A CG1 1 
ATOM 805  C CG2 . VAL A 1 123 ? 270.380 303.137 113.942 1.00 12.14  ? 123 VAL A CG2 1 
ATOM 806  N N   . GLU A 1 124 ? 266.103 301.769 112.928 1.00 19.68  ? 124 GLU A N   1 
ATOM 807  C CA  . GLU A 1 124 ? 264.787 301.583 112.329 1.00 19.68  ? 124 GLU A CA  1 
ATOM 808  C C   . GLU A 1 124 ? 263.766 302.485 112.998 1.00 19.68  ? 124 GLU A C   1 
ATOM 809  O O   . GLU A 1 124 ? 262.881 303.032 112.335 1.00 19.68  ? 124 GLU A O   1 
ATOM 810  C CB  . GLU A 1 124 ? 264.352 300.125 112.443 1.00 19.68  ? 124 GLU A CB  1 
ATOM 811  C CG  . GLU A 1 124 ? 265.306 299.140 111.820 1.00 19.68  ? 124 GLU A CG  1 
ATOM 812  C CD  . GLU A 1 124 ? 264.688 297.763 111.632 1.00 19.68  ? 124 GLU A CD  1 
ATOM 813  O OE1 . GLU A 1 124 ? 264.230 297.461 110.509 1.00 19.68  ? 124 GLU A OE1 1 
ATOM 814  O OE2 . GLU A 1 124 ? 264.661 296.979 112.606 1.00 19.68  ? 124 GLU A OE2 1 
ATOM 815  N N   . LEU A 1 125 ? 263.905 302.684 114.307 1.00 11.65  ? 125 LEU A N   1 
ATOM 816  C CA  . LEU A 1 125 ? 262.940 303.459 115.068 1.00 11.65  ? 125 LEU A CA  1 
ATOM 817  C C   . LEU A 1 125 ? 263.168 304.955 114.951 1.00 11.65  ? 125 LEU A C   1 
ATOM 818  O O   . LEU A 1 125 ? 262.211 305.723 115.019 1.00 11.65  ? 125 LEU A O   1 
ATOM 819  C CB  . LEU A 1 125 ? 262.993 303.054 116.530 1.00 11.65  ? 125 LEU A CB  1 
ATOM 820  C CG  . LEU A 1 125 ? 261.729 303.321 117.322 1.00 11.65  ? 125 LEU A CG  1 
ATOM 821  C CD1 . LEU A 1 125 ? 260.732 302.291 116.935 1.00 11.65  ? 125 LEU A CD1 1 
ATOM 822  C CD2 . LEU A 1 125 ? 261.991 303.251 118.800 1.00 11.65  ? 125 LEU A CD2 1 
ATOM 823  N N   . LEU A 1 126 ? 264.407 305.398 114.789 1.00 10.39  ? 126 LEU A N   1 
ATOM 824  C CA  . LEU A 1 126 ? 264.690 306.814 114.620 1.00 10.39  ? 126 LEU A CA  1 
ATOM 825  C C   . LEU A 1 126 ? 264.637 307.258 113.176 1.00 10.39  ? 126 LEU A C   1 
ATOM 826  O O   . LEU A 1 126 ? 265.183 308.312 112.847 1.00 10.39  ? 126 LEU A O   1 
ATOM 827  C CB  . LEU A 1 126 ? 266.053 307.185 115.205 1.00 10.39  ? 126 LEU A CB  1 
ATOM 828  C CG  . LEU A 1 126 ? 266.143 307.531 116.685 1.00 10.39  ? 126 LEU A CG  1 
ATOM 829  C CD1 . LEU A 1 126 ? 266.199 306.314 117.563 1.00 10.39  ? 126 LEU A CD1 1 
ATOM 830  C CD2 . LEU A 1 126 ? 267.314 308.415 116.907 1.00 10.39  ? 126 LEU A CD2 1 
ATOM 831  N N   . SER A 1 127 ? 264.027 306.478 112.299 1.00 6.91   ? 127 SER A N   1 
ATOM 832  C CA  . SER A 1 127 ? 263.713 306.959 110.968 1.00 6.91   ? 127 SER A CA  1 
ATOM 833  C C   . SER A 1 127 ? 262.230 307.228 110.797 1.00 6.91   ? 127 SER A C   1 
ATOM 834  O O   . SER A 1 127 ? 261.817 307.664 109.719 1.00 6.91   ? 127 SER A O   1 
ATOM 835  C CB  . SER A 1 127 ? 264.193 305.979 109.901 1.00 6.91   ? 127 SER A CB  1 
ATOM 836  O OG  . SER A 1 127 ? 264.121 306.590 108.625 1.00 6.91   ? 127 SER A OG  1 
ATOM 837  N N   . PHE A 1 128 ? 261.424 306.947 111.825 1.00 8.43   ? 128 PHE A N   1 
ATOM 838  C CA  . PHE A 1 128 ? 260.087 307.521 111.918 1.00 8.43   ? 128 PHE A CA  1 
ATOM 839  C C   . PHE A 1 128 ? 260.172 309.033 111.870 1.00 8.43   ? 128 PHE A C   1 
ATOM 840  O O   . PHE A 1 128 ? 259.450 309.693 111.119 1.00 8.43   ? 128 PHE A O   1 
ATOM 841  C CB  . PHE A 1 128 ? 259.416 307.087 113.218 1.00 8.43   ? 128 PHE A CB  1 
ATOM 842  C CG  . PHE A 1 128 ? 259.044 305.632 113.273 1.00 8.43   ? 128 PHE A CG  1 
ATOM 843  C CD1 . PHE A 1 128 ? 258.999 304.854 112.136 1.00 8.43   ? 128 PHE A CD1 1 
ATOM 844  C CD2 . PHE A 1 128 ? 258.730 305.048 114.482 1.00 8.43   ? 128 PHE A CD2 1 
ATOM 845  C CE1 . PHE A 1 128 ? 258.667 303.540 112.213 1.00 8.43   ? 128 PHE A CE1 1 
ATOM 846  C CE2 . PHE A 1 128 ? 258.385 303.735 114.557 1.00 8.43   ? 128 PHE A CE2 1 
ATOM 847  C CZ  . PHE A 1 128 ? 258.358 302.984 113.430 1.00 8.43   ? 128 PHE A CZ  1 
ATOM 848  N N   . LEU A 1 129 ? 261.056 309.585 112.675 1.00 10.65  ? 129 LEU A N   1 
ATOM 849  C CA  . LEU A 1 129 ? 261.437 310.980 112.590 1.00 10.65  ? 129 LEU A CA  1 
ATOM 850  C C   . LEU A 1 129 ? 262.116 311.243 111.253 1.00 10.65  ? 129 LEU A C   1 
ATOM 851  O O   . LEU A 1 129 ? 263.061 310.532 110.900 1.00 10.65  ? 129 LEU A O   1 
ATOM 852  C CB  . LEU A 1 129 ? 262.397 311.285 113.730 1.00 10.65  ? 129 LEU A CB  1 
ATOM 853  C CG  . LEU A 1 129 ? 261.960 311.731 115.118 1.00 10.65  ? 129 LEU A CG  1 
ATOM 854  C CD1 . LEU A 1 129 ? 260.794 310.982 115.675 1.00 10.65  ? 129 LEU A CD1 1 
ATOM 855  C CD2 . LEU A 1 129 ? 263.126 311.495 116.009 1.00 10.65  ? 129 LEU A CD2 1 
ATOM 856  N N   . PRO A 1 130 ? 261.687 312.235 110.492 1.00 13.20  ? 130 PRO A N   1 
ATOM 857  C CA  . PRO A 1 130 ? 262.373 312.540 109.235 1.00 13.20  ? 130 PRO A CA  1 
ATOM 858  C C   . PRO A 1 130 ? 263.758 313.133 109.417 1.00 13.20  ? 130 PRO A C   1 
ATOM 859  O O   . PRO A 1 130 ? 264.258 313.258 110.535 1.00 13.20  ? 130 PRO A O   1 
ATOM 860  C CB  . PRO A 1 130 ? 261.431 313.542 108.560 1.00 13.20  ? 130 PRO A CB  1 
ATOM 861  C CG  . PRO A 1 130 ? 260.569 314.040 109.625 1.00 13.20  ? 130 PRO A CG  1 
ATOM 862  C CD  . PRO A 1 130 ? 260.393 312.915 110.562 1.00 13.20  ? 130 PRO A CD  1 
ATOM 863  N N   . SER A 1 131 ? 264.393 313.484 108.300 1.00 16.19  ? 131 SER A N   1 
ATOM 864  C CA  . SER A 1 131 ? 265.746 314.026 108.342 1.00 16.19  ? 131 SER A CA  1 
ATOM 865  C C   . SER A 1 131 ? 265.771 315.405 108.972 1.00 16.19  ? 131 SER A C   1 
ATOM 866  O O   . SER A 1 131 ? 266.590 315.680 109.853 1.00 16.19  ? 131 SER A O   1 
ATOM 867  C CB  . SER A 1 131 ? 266.325 314.085 106.935 1.00 16.19  ? 131 SER A CB  1 
ATOM 868  O OG  . SER A 1 131 ? 267.321 315.081 106.859 1.00 16.19  ? 131 SER A OG  1 
ATOM 869  N N   . ASP A 1 132 ? 264.877 316.285 108.541 1.00 21.15  ? 132 ASP A N   1 
ATOM 870  C CA  . ASP A 1 132 ? 264.882 317.668 108.979 1.00 21.15  ? 132 ASP A CA  1 
ATOM 871  C C   . ASP A 1 132 ? 264.005 317.907 110.192 1.00 21.15  ? 132 ASP A C   1 
ATOM 872  O O   . ASP A 1 132 ? 263.646 319.051 110.464 1.00 21.15  ? 132 ASP A O   1 
ATOM 873  C CB  . ASP A 1 132 ? 264.458 318.577 107.832 1.00 21.15  ? 132 ASP A CB  1 
ATOM 874  C CG  . ASP A 1 132 ? 263.281 318.034 107.078 1.00 21.15  ? 132 ASP A CG  1 
ATOM 875  O OD1 . ASP A 1 132 ? 262.864 316.902 107.376 1.00 21.15  ? 132 ASP A OD1 1 
ATOM 876  O OD2 . ASP A 1 132 ? 262.773 318.732 106.182 1.00 21.15  ? 132 ASP A OD2 1 
ATOM 877  N N   . PHE A 1 133 ? 263.647 316.859 110.923 1.00 28.56  ? 133 PHE A N   1 
ATOM 878  C CA  . PHE A 1 133 ? 263.013 317.062 112.214 1.00 28.56  ? 133 PHE A CA  1 
ATOM 879  C C   . PHE A 1 133 ? 264.010 317.595 113.221 1.00 28.56  ? 133 PHE A C   1 
ATOM 880  O O   . PHE A 1 133 ? 263.631 318.309 114.152 1.00 28.56  ? 133 PHE A O   1 
ATOM 881  C CB  . PHE A 1 133 ? 262.409 315.751 112.717 1.00 28.56  ? 133 PHE A CB  1 
ATOM 882  C CG  . PHE A 1 133 ? 262.027 315.772 114.162 1.00 28.56  ? 133 PHE A CG  1 
ATOM 883  C CD1 . PHE A 1 133 ? 260.872 316.391 114.562 1.00 28.56  ? 133 PHE A CD1 1 
ATOM 884  C CD2 . PHE A 1 133 ? 262.835 315.195 115.124 1.00 28.56  ? 133 PHE A CD2 1 
ATOM 885  C CE1 . PHE A 1 133 ? 260.530 316.421 115.885 1.00 28.56  ? 133 PHE A CE1 1 
ATOM 886  C CE2 . PHE A 1 133 ? 262.497 315.233 116.440 1.00 28.56  ? 133 PHE A CE2 1 
ATOM 887  C CZ  . PHE A 1 133 ? 261.350 315.841 116.821 1.00 28.56  ? 133 PHE A CZ  1 
ATOM 888  N N   . PHE A 1 134 ? 265.243 317.264 113.064 1.00 28.56  ? 134 PHE A N   1 
ATOM 889  C CA  . PHE A 1 134 ? 266.174 317.436 114.158 1.00 28.56  ? 134 PHE A CA  1 
ATOM 890  C C   . PHE A 1 134 ? 266.644 318.881 114.232 1.00 28.56  ? 134 PHE A C   1 
ATOM 891  O O   . PHE A 1 134 ? 266.870 319.512 113.197 1.00 28.56  ? 134 PHE A O   1 
ATOM 892  C CB  . PHE A 1 134 ? 267.352 316.499 113.986 1.00 28.56  ? 134 PHE A CB  1 
ATOM 893  C CG  . PHE A 1 134 ? 266.968 315.073 114.043 1.00 28.56  ? 134 PHE A CG  1 
ATOM 894  C CD1 . PHE A 1 134 ? 266.707 314.471 115.248 1.00 28.56  ? 134 PHE A CD1 1 
ATOM 895  C CD2 . PHE A 1 134 ? 266.808 314.349 112.894 1.00 28.56  ? 134 PHE A CD2 1 
ATOM 896  C CE1 . PHE A 1 134 ? 266.320 313.165 115.304 1.00 28.56  ? 134 PHE A CE1 1 
ATOM 897  C CE2 . PHE A 1 134 ? 266.421 313.052 112.954 1.00 28.56  ? 134 PHE A CE2 1 
ATOM 898  C CZ  . PHE A 1 134 ? 266.189 312.460 114.162 1.00 28.56  ? 134 PHE A CZ  1 
ATOM 899  N N   . PRO A 1 135 ? 266.764 319.428 115.440 1.00 20.07  ? 135 PRO A N   1 
ATOM 900  C CA  . PRO A 1 135 ? 267.285 320.783 115.593 1.00 20.07  ? 135 PRO A CA  1 
ATOM 901  C C   . PRO A 1 135 ? 268.732 320.851 115.153 1.00 20.07  ? 135 PRO A C   1 
ATOM 902  O O   . PRO A 1 135 ? 269.408 319.834 115.018 1.00 20.07  ? 135 PRO A O   1 
ATOM 903  C CB  . PRO A 1 135 ? 267.154 321.045 117.093 1.00 20.07  ? 135 PRO A CB  1 
ATOM 904  C CG  . PRO A 1 135 ? 266.229 320.018 117.587 1.00 20.07  ? 135 PRO A CG  1 
ATOM 905  C CD  . PRO A 1 135 ? 266.388 318.839 116.729 1.00 20.07  ? 135 PRO A CD  1 
ATOM 906  N N   . SER A 1 136 ? 269.212 322.070 114.942 1.00 18.60  ? 136 SER A N   1 
ATOM 907  C CA  . SER A 1 136 ? 270.570 322.251 114.467 1.00 18.60  ? 136 SER A CA  1 
ATOM 908  C C   . SER A 1 136 ? 271.572 321.845 115.543 1.00 18.60  ? 136 SER A C   1 
ATOM 909  O O   . SER A 1 136 ? 271.222 321.620 116.702 1.00 18.60  ? 136 SER A O   1 
ATOM 910  C CB  . SER A 1 136 ? 270.794 323.693 114.045 1.00 18.60  ? 136 SER A CB  1 
ATOM 911  O OG  . SER A 1 136 ? 272.173 323.947 113.913 1.00 18.60  ? 136 SER A OG  1 
ATOM 912  N N   . VAL A 1 137 ? 272.836 321.713 115.143 1.00 19.24  ? 137 VAL A N   1 
ATOM 913  C CA  . VAL A 1 137 ? 273.839 321.233 116.085 1.00 19.24  ? 137 VAL A CA  1 
ATOM 914  C C   . VAL A 1 137 ? 274.142 322.303 117.115 1.00 19.24  ? 137 VAL A C   1 
ATOM 915  O O   . VAL A 1 137 ? 274.461 322.002 118.268 1.00 19.24  ? 137 VAL A O   1 
ATOM 916  C CB  . VAL A 1 137 ? 275.113 320.797 115.354 1.00 19.24  ? 137 VAL A CB  1 
ATOM 917  C CG1 . VAL A 1 137 ? 275.847 319.792 116.190 1.00 19.24  ? 137 VAL A CG1 1 
ATOM 918  C CG2 . VAL A 1 137 ? 274.791 320.251 113.991 1.00 19.24  ? 137 VAL A CG2 1 
ATOM 919  N N   . ARG A 1 138 ? 274.034 323.568 116.713 1.00 30.06  ? 138 ARG A N   1 
ATOM 920  C CA  . ARG A 1 138 ? 274.139 324.675 117.652 1.00 30.06  ? 138 ARG A CA  1 
ATOM 921  C C   . ARG A 1 138 ? 273.035 324.622 118.689 1.00 30.06  ? 138 ARG A C   1 
ATOM 922  O O   . ARG A 1 138 ? 273.306 324.730 119.889 1.00 30.06  ? 138 ARG A O   1 
ATOM 923  C CB  . ARG A 1 138 ? 274.080 325.991 116.898 1.00 30.06  ? 138 ARG A CB  1 
ATOM 924  C CG  . ARG A 1 138 ? 274.796 325.935 115.579 1.00 30.06  ? 138 ARG A CG  1 
ATOM 925  C CD  . ARG A 1 138 ? 274.535 327.182 114.772 1.00 30.06  ? 138 ARG A CD  1 
ATOM 926  N NE  . ARG A 1 138 ? 273.251 327.119 114.086 1.00 30.06  ? 138 ARG A NE  1 
ATOM 927  C CZ  . ARG A 1 138 ? 273.113 327.010 112.771 1.00 30.06  ? 138 ARG A CZ  1 
ATOM 928  N NH1 . ARG A 1 138 ? 274.183 326.954 111.996 1.00 30.06  ? 138 ARG A NH1 1 
ATOM 929  N NH2 . ARG A 1 138 ? 271.906 326.963 112.230 1.00 30.06  ? 138 ARG A NH2 1 
ATOM 930  N N   . ASP A 1 139 ? 271.790 324.429 118.246 1.00 22.24  ? 139 ASP A N   1 
ATOM 931  C CA  . ASP A 1 139 ? 270.649 324.426 119.150 1.00 22.24  ? 139 ASP A CA  1 
ATOM 932  C C   . ASP A 1 139 ? 270.632 323.222 120.077 1.00 22.24  ? 139 ASP A C   1 
ATOM 933  O O   . ASP A 1 139 ? 269.984 323.272 121.124 1.00 22.24  ? 139 ASP A O   1 
ATOM 934  C CB  . ASP A 1 139 ? 269.350 324.481 118.360 1.00 22.24  ? 139 ASP A CB  1 
ATOM 935  C CG  . ASP A 1 139 ? 269.243 325.719 117.516 1.00 22.24  ? 139 ASP A CG  1 
ATOM 936  O OD1 . ASP A 1 139 ? 270.176 326.539 117.556 1.00 22.24  ? 139 ASP A OD1 1 
ATOM 937  O OD2 . ASP A 1 139 ? 268.216 325.885 116.828 1.00 22.24  ? 139 ASP A OD2 1 
ATOM 938  N N   . LEU A 1 140 ? 271.325 322.151 119.731 1.00 18.85  ? 140 LEU A N   1 
ATOM 939  C CA  . LEU A 1 140 ? 271.427 321.023 120.636 1.00 18.85  ? 140 LEU A CA  1 
ATOM 940  C C   . LEU A 1 140 ? 272.628 321.135 121.548 1.00 18.85  ? 140 LEU A C   1 
ATOM 941  O O   . LEU A 1 140 ? 272.555 320.748 122.721 1.00 18.85  ? 140 LEU A O   1 
ATOM 942  C CB  . LEU A 1 140 ? 271.505 319.725 119.842 1.00 18.85  ? 140 LEU A CB  1 
ATOM 943  C CG  . LEU A 1 140 ? 270.208 319.311 119.176 1.00 18.85  ? 140 LEU A CG  1 
ATOM 944  C CD1 . LEU A 1 140 ? 270.508 318.441 118.004 1.00 18.85  ? 140 LEU A CD1 1 
ATOM 945  C CD2 . LEU A 1 140 ? 269.354 318.589 120.183 1.00 18.85  ? 140 LEU A CD2 1 
ATOM 946  N N   . LEU A 1 141 ? 273.723 321.696 121.044 1.00 18.53  ? 141 LEU A N   1 
ATOM 947  C CA  . LEU A 1 141 ? 274.902 321.865 121.873 1.00 18.53  ? 141 LEU A CA  1 
ATOM 948  C C   . LEU A 1 141 ? 274.684 322.904 122.960 1.00 18.53  ? 141 LEU A C   1 
ATOM 949  O O   . LEU A 1 141 ? 275.171 322.720 124.077 1.00 18.53  ? 141 LEU A O   1 
ATOM 950  C CB  . LEU A 1 141 ? 276.100 322.219 121.004 1.00 18.53  ? 141 LEU A CB  1 
ATOM 951  C CG  . LEU A 1 141 ? 276.732 320.971 120.393 1.00 18.53  ? 141 LEU A CG  1 
ATOM 952  C CD1 . LEU A 1 141 ? 277.621 321.351 119.257 1.00 18.53  ? 141 LEU A CD1 1 
ATOM 953  C CD2 . LEU A 1 141 ? 277.492 320.194 121.428 1.00 18.53  ? 141 LEU A CD2 1 
ATOM 954  N N   . ASP A 1 142 ? 273.908 323.961 122.702 1.00 19.88  ? 142 ASP A N   1 
ATOM 955  C CA  . ASP A 1 142 ? 273.683 324.894 123.798 1.00 19.88  ? 142 ASP A CA  1 
ATOM 956  C C   . ASP A 1 142 ? 272.565 324.466 124.737 1.00 19.88  ? 142 ASP A C   1 
ATOM 957  O O   . ASP A 1 142 ? 272.544 324.918 125.879 1.00 19.88  ? 142 ASP A O   1 
ATOM 958  C CB  . ASP A 1 142 ? 273.426 326.318 123.304 1.00 19.88  ? 142 ASP A CB  1 
ATOM 959  C CG  . ASP A 1 142 ? 272.372 326.403 122.259 1.00 19.88  ? 142 ASP A CG  1 
ATOM 960  O OD1 . ASP A 1 142 ? 271.641 325.426 122.067 1.00 19.88  ? 142 ASP A OD1 1 
ATOM 961  O OD2 . ASP A 1 142 ? 272.274 327.463 121.607 1.00 19.88  ? 142 ASP A OD2 1 
ATOM 962  N N   . THR A 1 143 ? 271.662 323.588 124.307 1.00 14.04  ? 143 THR A N   1 
ATOM 963  C CA  . THR A 1 143 ? 270.760 322.941 125.255 1.00 14.04  ? 143 THR A CA  1 
ATOM 964  C C   . THR A 1 143 ? 271.530 322.027 126.193 1.00 14.04  ? 143 THR A C   1 
ATOM 965  O O   . THR A 1 143 ? 271.256 321.984 127.400 1.00 14.04  ? 143 THR A O   1 
ATOM 966  C CB  . THR A 1 143 ? 269.696 322.153 124.505 1.00 14.04  ? 143 THR A CB  1 
ATOM 967  O OG1 . THR A 1 143 ? 268.997 323.026 123.616 1.00 14.04  ? 143 THR A OG1 1 
ATOM 968  C CG2 . THR A 1 143 ? 268.716 321.544 125.454 1.00 14.04  ? 143 THR A CG2 1 
ATOM 969  N N   . ALA A 1 144 ? 272.526 321.319 125.658 1.00 14.77  ? 144 ALA A N   1 
ATOM 970  C CA  . ALA A 1 144 ? 273.360 320.468 126.496 1.00 14.77  ? 144 ALA A CA  1 
ATOM 971  C C   . ALA A 1 144 ? 274.238 321.291 127.419 1.00 14.77  ? 144 ALA A C   1 
ATOM 972  O O   . ALA A 1 144 ? 274.430 320.931 128.583 1.00 14.77  ? 144 ALA A O   1 
ATOM 973  C CB  . ALA A 1 144 ? 274.217 319.562 125.624 1.00 14.77  ? 144 ALA A CB  1 
ATOM 974  N N   . SER A 1 145 ? 274.769 322.404 126.926 1.00 15.26  ? 145 SER A N   1 
ATOM 975  C CA  . SER A 1 145 ? 275.622 323.264 127.725 1.00 15.26  ? 145 SER A CA  1 
ATOM 976  C C   . SER A 1 145 ? 274.843 324.177 128.647 1.00 15.26  ? 145 SER A C   1 
ATOM 977  O O   . SER A 1 145 ? 275.450 324.825 129.500 1.00 15.26  ? 145 SER A O   1 
ATOM 978  C CB  . SER A 1 145 ? 276.497 324.119 126.826 1.00 15.26  ? 145 SER A CB  1 
ATOM 979  O OG  . SER A 1 145 ? 275.838 325.328 126.554 1.00 15.26  ? 145 SER A OG  1 
ATOM 980  N N   . ALA A 1 146 ? 273.531 324.273 128.478 1.00 11.30  ? 146 ALA A N   1 
ATOM 981  C CA  . ALA A 1 146 ? 272.696 325.018 129.397 1.00 11.30  ? 146 ALA A CA  1 
ATOM 982  C C   . ALA A 1 146 ? 272.167 324.144 130.511 1.00 11.30  ? 146 ALA A C   1 
ATOM 983  O O   . ALA A 1 146 ? 272.081 324.592 131.656 1.00 11.30  ? 146 ALA A O   1 
ATOM 984  C CB  . ALA A 1 146 ? 271.530 325.652 128.646 1.00 11.30  ? 146 ALA A CB  1 
ATOM 985  N N   . LEU A 1 147 ? 271.825 322.897 130.205 1.00 10.94  ? 147 LEU A N   1 
ATOM 986  C CA  . LEU A 1 147 ? 271.121 322.065 131.166 1.00 10.94  ? 147 LEU A CA  1 
ATOM 987  C C   . LEU A 1 147 ? 271.986 321.022 131.853 1.00 10.94  ? 147 LEU A C   1 
ATOM 988  O O   . LEU A 1 147 ? 271.635 320.592 132.954 1.00 10.94  ? 147 LEU A O   1 
ATOM 989  C CB  . LEU A 1 147 ? 269.960 321.360 130.476 1.00 10.94  ? 147 LEU A CB  1 
ATOM 990  C CG  . LEU A 1 147 ? 268.625 322.063 130.355 1.00 10.94  ? 147 LEU A CG  1 
ATOM 991  C CD1 . LEU A 1 147 ? 268.006 321.635 129.084 1.00 10.94  ? 147 LEU A CD1 1 
ATOM 992  C CD2 . LEU A 1 147 ? 267.763 321.630 131.491 1.00 10.94  ? 147 LEU A CD2 1 
ATOM 993  N N   . TYR A 1 148 ? 273.085 320.582 131.235 1.00 15.22  ? 148 TYR A N   1 
ATOM 994  C CA  . TYR A 1 148 ? 273.863 319.474 131.778 1.00 15.22  ? 148 TYR A CA  1 
ATOM 995  C C   . TYR A 1 148 ? 275.356 319.744 131.856 1.00 15.22  ? 148 TYR A C   1 
ATOM 996  O O   . TYR A 1 148 ? 276.116 318.794 132.046 1.00 15.22  ? 148 TYR A O   1 
ATOM 997  C CB  . TYR A 1 148 ? 273.653 318.199 130.954 1.00 15.22  ? 148 TYR A CB  1 
ATOM 998  C CG  . TYR A 1 148 ? 272.224 317.934 130.615 1.00 15.22  ? 148 TYR A CG  1 
ATOM 999  C CD1 . TYR A 1 148 ? 271.323 317.551 131.595 1.00 15.22  ? 148 TYR A CD1 1 
ATOM 1000 C CD2 . TYR A 1 148 ? 271.767 318.090 129.321 1.00 15.22  ? 148 TYR A CD2 1 
ATOM 1001 C CE1 . TYR A 1 148 ? 270.018 317.339 131.298 1.00 15.22  ? 148 TYR A CE1 1 
ATOM 1002 C CE2 . TYR A 1 148 ? 270.463 317.866 129.017 1.00 15.22  ? 148 TYR A CE2 1 
ATOM 1003 C CZ  . TYR A 1 148 ? 269.598 317.491 130.011 1.00 15.22  ? 148 TYR A CZ  1 
ATOM 1004 O OH  . TYR A 1 148 ? 268.291 317.276 129.708 1.00 15.22  ? 148 TYR A OH  1 
ATOM 1005 N N   . ARG A 1 149 ? 275.795 321.000 131.733 1.00 19.60  ? 149 ARG A N   1 
ATOM 1006 C CA  . ARG A 1 149 ? 277.221 321.297 131.637 1.00 19.60  ? 149 ARG A CA  1 
ATOM 1007 C C   . ARG A 1 149 ? 277.975 320.949 132.908 1.00 19.60  ? 149 ARG A C   1 
ATOM 1008 O O   . ARG A 1 149 ? 279.165 320.638 132.852 1.00 19.60  ? 149 ARG A O   1 
ATOM 1009 C CB  . ARG A 1 149 ? 277.426 322.768 131.309 1.00 19.60  ? 149 ARG A CB  1 
ATOM 1010 C CG  . ARG A 1 149 ? 278.791 323.096 130.768 1.00 19.60  ? 149 ARG A CG  1 
ATOM 1011 C CD  . ARG A 1 149 ? 278.734 324.328 129.915 1.00 19.60  ? 149 ARG A CD  1 
ATOM 1012 N NE  . ARG A 1 149 ? 280.057 324.834 129.614 1.00 19.60  ? 149 ARG A NE  1 
ATOM 1013 C CZ  . ARG A 1 149 ? 280.683 325.727 130.361 1.00 19.60  ? 149 ARG A CZ  1 
ATOM 1014 N NH1 . ARG A 1 149 ? 280.095 326.199 131.449 1.00 19.60  ? 149 ARG A NH1 1 
ATOM 1015 N NH2 . ARG A 1 149 ? 281.896 326.141 130.027 1.00 19.60  ? 149 ARG A NH2 1 
ATOM 1016 N N   . GLU A 1 150 ? 277.306 320.975 134.054 1.00 20.61  ? 150 GLU A N   1 
ATOM 1017 C CA  . GLU A 1 150 ? 277.974 320.609 135.293 1.00 20.61  ? 150 GLU A CA  1 
ATOM 1018 C C   . GLU A 1 150 ? 278.265 319.121 135.330 1.00 20.61  ? 150 GLU A C   1 
ATOM 1019 O O   . GLU A 1 150 ? 279.367 318.708 135.697 1.00 20.61  ? 150 GLU A O   1 
ATOM 1020 C CB  . GLU A 1 150 ? 277.127 321.015 136.496 1.00 20.61  ? 150 GLU A CB  1 
ATOM 1021 C CG  . GLU A 1 150 ? 277.918 321.167 137.793 1.00 20.61  ? 150 GLU A CG  1 
ATOM 1022 C CD  . GLU A 1 150 ? 278.082 319.862 138.566 1.00 20.61  ? 150 GLU A CD  1 
ATOM 1023 O OE1 . GLU A 1 150 ? 279.030 319.759 139.376 1.00 20.61  ? 150 GLU A OE1 1 
ATOM 1024 O OE2 . GLU A 1 150 ? 277.259 318.944 138.372 1.00 20.61  ? 150 GLU A OE2 1 
ATOM 1025 N N   . ALA A 1 151 ? 277.294 318.300 134.948 1.00 13.87  ? 151 ALA A N   1 
ATOM 1026 C CA  . ALA A 1 151 ? 277.460 316.859 134.987 1.00 13.87  ? 151 ALA A CA  1 
ATOM 1027 C C   . ALA A 1 151 ? 278.093 316.300 133.726 1.00 13.87  ? 151 ALA A C   1 
ATOM 1028 O O   . ALA A 1 151 ? 278.577 315.169 133.751 1.00 13.87  ? 151 ALA A O   1 
ATOM 1029 C CB  . ALA A 1 151 ? 276.117 316.184 135.232 1.00 13.87  ? 151 ALA A CB  1 
ATOM 1030 N N   . LEU A 1 152 ? 278.123 317.051 132.633 1.00 17.88  ? 152 LEU A N   1 
ATOM 1031 C CA  . LEU A 1 152 ? 278.905 316.661 131.472 1.00 17.88  ? 152 LEU A CA  1 
ATOM 1032 C C   . LEU A 1 152 ? 280.343 317.125 131.563 1.00 17.88  ? 152 LEU A C   1 
ATOM 1033 O O   . LEU A 1 152 ? 281.038 317.146 130.548 1.00 17.88  ? 152 LEU A O   1 
ATOM 1034 C CB  . LEU A 1 152 ? 278.295 317.211 130.187 1.00 17.88  ? 152 LEU A CB  1 
ATOM 1035 C CG  . LEU A 1 152 ? 276.994 316.639 129.652 1.00 17.88  ? 152 LEU A CG  1 
ATOM 1036 C CD1 . LEU A 1 152 ? 276.816 317.160 128.275 1.00 17.88  ? 152 LEU A CD1 1 
ATOM 1037 C CD2 . LEU A 1 152 ? 277.011 315.147 129.636 1.00 17.88  ? 152 LEU A CD2 1 
ATOM 1038 N N   . GLU A 1 153 ? 280.789 317.536 132.742 1.00 16.90  ? 153 GLU A N   1 
ATOM 1039 C CA  . GLU A 1 153 ? 282.169 317.926 132.989 1.00 16.90  ? 153 GLU A CA  1 
ATOM 1040 C C   . GLU A 1 153 ? 282.641 317.394 134.333 1.00 16.90  ? 153 GLU A C   1 
ATOM 1041 O O   . GLU A 1 153 ? 283.631 317.888 134.872 1.00 16.90  ? 153 GLU A O   1 
ATOM 1042 C CB  . GLU A 1 153 ? 282.323 319.442 132.967 1.00 16.90  ? 153 GLU A CB  1 
ATOM 1043 C CG  . GLU A 1 153 ? 282.223 320.060 131.602 1.00 16.90  ? 153 GLU A CG  1 
ATOM 1044 C CD  . GLU A 1 153 ? 282.521 321.539 131.610 1.00 16.90  ? 153 GLU A CD  1 
ATOM 1045 O OE1 . GLU A 1 153 ? 282.228 322.202 132.624 1.00 16.90  ? 153 GLU A OE1 1 
ATOM 1046 O OE2 . GLU A 1 153 ? 283.057 322.042 130.601 1.00 16.90  ? 153 GLU A OE2 1 
ATOM 1047 N N   . SER A 1 154 ? 281.953 316.411 134.890 1.00 18.97  ? 154 SER A N   1 
ATOM 1048 C CA  . SER A 1 154 ? 282.191 315.996 136.250 1.00 18.97  ? 154 SER A CA  1 
ATOM 1049 C C   . SER A 1 154 ? 282.697 314.564 136.264 1.00 18.97  ? 154 SER A C   1 
ATOM 1050 O O   . SER A 1 154 ? 282.218 313.729 135.494 1.00 18.97  ? 154 SER A O   1 
ATOM 1051 C CB  . SER A 1 154 ? 280.914 316.098 137.078 1.00 18.97  ? 154 SER A CB  1 
ATOM 1052 O OG  . SER A 1 154 ? 280.201 314.884 137.006 1.00 18.97  ? 154 SER A OG  1 
ATOM 1053 N N   . PRO A 1 155 ? 283.643 314.246 137.128 1.00 21.66  ? 155 PRO A N   1 
ATOM 1054 C CA  . PRO A 1 155 ? 284.283 312.928 137.085 1.00 21.66  ? 155 PRO A CA  1 
ATOM 1055 C C   . PRO A 1 155 ? 283.480 311.840 137.788 1.00 21.66  ? 155 PRO A C   1 
ATOM 1056 O O   . PRO A 1 155 ? 283.935 311.225 138.753 1.00 21.66  ? 155 PRO A O   1 
ATOM 1057 C CB  . PRO A 1 155 ? 285.617 313.203 137.781 1.00 21.66  ? 155 PRO A CB  1 
ATOM 1058 C CG  . PRO A 1 155 ? 285.274 314.230 138.772 1.00 21.66  ? 155 PRO A CG  1 
ATOM 1059 C CD  . PRO A 1 155 ? 284.320 315.136 138.084 1.00 21.66  ? 155 PRO A CD  1 
ATOM 1060 N N   . GLU A 1 156 ? 282.274 311.583 137.289 1.00 27.26  ? 156 GLU A N   1 
ATOM 1061 C CA  . GLU A 1 156 ? 281.555 310.369 137.646 1.00 27.26  ? 156 GLU A CA  1 
ATOM 1062 C C   . GLU A 1 156 ? 280.616 310.023 136.508 1.00 27.26  ? 156 GLU A C   1 
ATOM 1063 O O   . GLU A 1 156 ? 280.379 310.832 135.611 1.00 27.26  ? 156 GLU A O   1 
ATOM 1064 C CB  . GLU A 1 156 ? 280.786 310.507 138.966 1.00 27.26  ? 156 GLU A CB  1 
ATOM 1065 C CG  . GLU A 1 156 ? 279.486 311.248 138.888 1.00 27.26  ? 156 GLU A CG  1 
ATOM 1066 C CD  . GLU A 1 156 ? 279.631 312.713 139.200 1.00 27.26  ? 156 GLU A CD  1 
ATOM 1067 O OE1 . GLU A 1 156 ? 280.759 313.229 139.125 1.00 27.26  ? 156 GLU A OE1 1 
ATOM 1068 O OE2 . GLU A 1 156 ? 278.616 313.360 139.518 1.00 27.26  ? 156 GLU A OE2 1 
ATOM 1069 N N   . HIS A 1 157 ? 280.114 308.796 136.537 1.00 28.80  ? 157 HIS A N   1 
ATOM 1070 C CA  . HIS A 1 157 ? 279.080 308.363 135.612 1.00 28.80  ? 157 HIS A CA  1 
ATOM 1071 C C   . HIS A 1 157 ? 277.741 308.643 136.258 1.00 28.80  ? 157 HIS A C   1 
ATOM 1072 O O   . HIS A 1 157 ? 277.371 307.978 137.230 1.00 28.80  ? 157 HIS A O   1 
ATOM 1073 C CB  . HIS A 1 157 ? 279.179 306.874 135.316 1.00 28.80  ? 157 HIS A CB  1 
ATOM 1074 C CG  . HIS A 1 157 ? 280.534 306.438 134.891 1.00 28.80  ? 157 HIS A CG  1 
ATOM 1075 N ND1 . HIS A 1 157 ? 281.082 306.801 133.682 1.00 28.80  ? 157 HIS A ND1 1 
ATOM 1076 C CD2 . HIS A 1 157 ? 281.448 305.653 135.506 1.00 28.80  ? 157 HIS A CD2 1 
ATOM 1077 C CE1 . HIS A 1 157 ? 282.282 306.267 133.578 1.00 28.80  ? 157 HIS A CE1 1 
ATOM 1078 N NE2 . HIS A 1 157 ? 282.526 305.561 134.668 1.00 28.80  ? 157 HIS A NE2 1 
ATOM 1079 N N   . CYS A 1 158 ? 277.017 309.610 135.736 1.00 26.81  ? 158 CYS A N   1 
ATOM 1080 C CA  . CYS A 1 158 ? 275.691 309.804 136.275 1.00 26.81  ? 158 CYS A CA  1 
ATOM 1081 C C   . CYS A 1 158 ? 274.651 308.958 135.556 1.00 26.81  ? 158 CYS A C   1 
ATOM 1082 O O   . CYS A 1 158 ? 273.619 308.642 136.157 1.00 26.81  ? 158 CYS A O   1 
ATOM 1083 C CB  . CYS A 1 158 ? 275.326 311.287 136.237 1.00 26.81  ? 158 CYS A CB  1 
ATOM 1084 S SG  . CYS A 1 158 ? 276.385 312.346 137.238 1.00 26.81  ? 158 CYS A SG  1 
ATOM 1085 N N   . SER A 1 159 ? 274.919 308.547 134.307 1.00 21.05  ? 159 SER A N   1 
ATOM 1086 C CA  . SER A 1 159 ? 274.025 307.703 133.524 1.00 21.05  ? 159 SER A CA  1 
ATOM 1087 C C   . SER A 1 159 ? 274.774 307.147 132.321 1.00 21.05  ? 159 SER A C   1 
ATOM 1088 O O   . SER A 1 159 ? 275.884 307.600 132.033 1.00 21.05  ? 159 SER A O   1 
ATOM 1089 C CB  . SER A 1 159 ? 272.814 308.493 133.035 1.00 21.05  ? 159 SER A CB  1 
ATOM 1090 O OG  . SER A 1 159 ? 273.162 309.280 131.918 1.00 21.05  ? 159 SER A OG  1 
ATOM 1091 N N   . PRO A 1 160 ? 274.227 306.163 131.603 1.00 19.28  ? 160 PRO A N   1 
ATOM 1092 C CA  . PRO A 1 160 ? 274.770 305.838 130.278 1.00 19.28  ? 160 PRO A CA  1 
ATOM 1093 C C   . PRO A 1 160 ? 274.544 306.910 129.236 1.00 19.28  ? 160 PRO A C   1 
ATOM 1094 O O   . PRO A 1 160 ? 275.273 306.951 128.239 1.00 19.28  ? 160 PRO A O   1 
ATOM 1095 C CB  . PRO A 1 160 ? 274.023 304.561 129.913 1.00 19.28  ? 160 PRO A CB  1 
ATOM 1096 C CG  . PRO A 1 160 ? 273.704 303.957 131.204 1.00 19.28  ? 160 PRO A CG  1 
ATOM 1097 C CD  . PRO A 1 160 ? 273.388 305.067 132.113 1.00 19.28  ? 160 PRO A CD  1 
ATOM 1098 N N   . HIS A 1 161 ? 273.552 307.775 129.428 1.00 28.56  ? 161 HIS A N   1 
ATOM 1099 C CA  . HIS A 1 161 ? 273.302 308.845 128.476 1.00 28.56  ? 161 HIS A CA  1 
ATOM 1100 C C   . HIS A 1 161 ? 274.347 309.929 128.575 1.00 28.56  ? 161 HIS A C   1 
ATOM 1101 O O   . HIS A 1 161 ? 274.664 310.575 127.575 1.00 28.56  ? 161 HIS A O   1 
ATOM 1102 C CB  . HIS A 1 161 ? 271.923 309.436 128.708 1.00 28.56  ? 161 HIS A CB  1 
ATOM 1103 C CG  . HIS A 1 161 ? 270.807 308.515 128.342 1.00 28.56  ? 161 HIS A CG  1 
ATOM 1104 N ND1 . HIS A 1 161 ? 270.510 308.200 127.037 1.00 28.56  ? 161 HIS A ND1 1 
ATOM 1105 C CD2 . HIS A 1 161 ? 269.925 307.833 129.107 1.00 28.56  ? 161 HIS A CD2 1 
ATOM 1106 C CE1 . HIS A 1 161 ? 269.494 307.361 127.015 1.00 28.56  ? 161 HIS A CE1 1 
ATOM 1107 N NE2 . HIS A 1 161 ? 269.116 307.128 128.256 1.00 28.56  ? 161 HIS A NE2 1 
ATOM 1108 N N   . HIS A 1 162 ? 274.910 310.124 129.764 1.00 21.09  ? 162 HIS A N   1 
ATOM 1109 C CA  . HIS A 1 162 ? 275.979 311.097 129.929 1.00 21.09  ? 162 HIS A CA  1 
ATOM 1110 C C   . HIS A 1 162 ? 277.246 310.632 129.234 1.00 21.09  ? 162 HIS A C   1 
ATOM 1111 O O   . HIS A 1 162 ? 277.898 311.410 128.525 1.00 21.09  ? 162 HIS A O   1 
ATOM 1112 C CB  . HIS A 1 162 ? 276.235 311.333 131.407 1.00 21.09  ? 162 HIS A CB  1 
ATOM 1113 C CG  . HIS A 1 162 ? 275.203 312.183 132.074 1.00 21.09  ? 162 HIS A CG  1 
ATOM 1114 N ND1 . HIS A 1 162 ? 275.046 313.520 131.790 1.00 21.09  ? 162 HIS A ND1 1 
ATOM 1115 C CD2 . HIS A 1 162 ? 274.286 311.891 133.022 1.00 21.09  ? 162 HIS A CD2 1 
ATOM 1116 C CE1 . HIS A 1 162 ? 274.074 314.013 132.532 1.00 21.09  ? 162 HIS A CE1 1 
ATOM 1117 N NE2 . HIS A 1 162 ? 273.599 313.045 133.290 1.00 21.09  ? 162 HIS A NE2 1 
ATOM 1118 N N   . THR A 1 163 ? 277.608 309.362 129.444 1.00 11.75  ? 163 THR A N   1 
ATOM 1119 C CA  . THR A 1 163 ? 278.743 308.758 128.755 1.00 11.75  ? 163 THR A CA  1 
ATOM 1120 C C   . THR A 1 163 ? 278.549 308.782 127.251 1.00 11.75  ? 163 THR A C   1 
ATOM 1121 O O   . THR A 1 163 ? 279.493 309.033 126.503 1.00 11.75  ? 163 THR A O   1 
ATOM 1122 C CB  . THR A 1 163 ? 278.941 307.321 129.229 1.00 11.75  ? 163 THR A CB  1 
ATOM 1123 O OG1 . THR A 1 163 ? 279.013 307.287 130.654 1.00 11.75  ? 163 THR A OG1 1 
ATOM 1124 C CG2 . THR A 1 163 ? 280.201 306.751 128.679 1.00 11.75  ? 163 THR A CG2 1 
ATOM 1125 N N   . ALA A 1 164 ? 277.329 308.556 126.787 1.00 14.75  ? 164 ALA A N   1 
ATOM 1126 C CA  . ALA A 1 164 ? 277.099 308.576 125.357 1.00 14.75  ? 164 ALA A CA  1 
ATOM 1127 C C   . ALA A 1 164 ? 276.998 309.982 124.791 1.00 14.75  ? 164 ALA A C   1 
ATOM 1128 O O   . ALA A 1 164 ? 277.119 310.153 123.578 1.00 14.75  ? 164 ALA A O   1 
ATOM 1129 C CB  . ALA A 1 164 ? 275.841 307.786 125.040 1.00 14.75  ? 164 ALA A CB  1 
ATOM 1130 N N   . LEU A 1 165 ? 276.788 310.991 125.633 1.00 28.56  ? 165 LEU A N   1 
ATOM 1131 C CA  . LEU A 1 165 ? 276.655 312.361 125.161 1.00 28.56  ? 165 LEU A CA  1 
ATOM 1132 C C   . LEU A 1 165 ? 277.985 313.097 125.119 1.00 28.56  ? 165 LEU A C   1 
ATOM 1133 O O   . LEU A 1 165 ? 278.203 313.917 124.215 1.00 28.56  ? 165 LEU A O   1 
ATOM 1134 C CB  . LEU A 1 165 ? 275.664 313.107 126.049 1.00 28.56  ? 165 LEU A CB  1 
ATOM 1135 C CG  . LEU A 1 165 ? 275.161 314.474 125.610 1.00 28.56  ? 165 LEU A CG  1 
ATOM 1136 C CD1 . LEU A 1 165 ? 274.719 314.396 124.200 1.00 28.56  ? 165 LEU A CD1 1 
ATOM 1137 C CD2 . LEU A 1 165 ? 274.027 314.932 126.495 1.00 28.56  ? 165 LEU A CD2 1 
ATOM 1138 N N   . ARG A 1 166 ? 278.868 312.806 126.084 1.00 10.65  ? 166 ARG A N   1 
ATOM 1139 C CA  . ARG A 1 166 ? 280.228 313.346 126.072 1.00 10.65  ? 166 ARG A CA  1 
ATOM 1140 C C   . ARG A 1 166 ? 280.968 312.969 124.801 1.00 10.65  ? 166 ARG A C   1 
ATOM 1141 O O   . ARG A 1 166 ? 281.638 313.806 124.188 1.00 10.65  ? 166 ARG A O   1 
ATOM 1142 C CB  . ARG A 1 166 ? 281.009 312.837 127.280 1.00 10.65  ? 166 ARG A CB  1 
ATOM 1143 C CG  . ARG A 1 166 ? 280.580 313.411 128.593 1.00 10.65  ? 166 ARG A CG  1 
ATOM 1144 C CD  . ARG A 1 166 ? 280.919 312.522 129.742 1.00 10.65  ? 166 ARG A CD  1 
ATOM 1145 N NE  . ARG A 1 166 ? 280.446 313.106 130.979 1.00 10.65  ? 166 ARG A NE  1 
ATOM 1146 C CZ  . ARG A 1 166 ? 280.071 312.411 132.037 1.00 10.65  ? 166 ARG A CZ  1 
ATOM 1147 N NH1 . ARG A 1 166 ? 279.651 313.028 133.122 1.00 10.65  ? 166 ARG A NH1 1 
ATOM 1148 N NH2 . ARG A 1 166 ? 280.106 311.102 132.010 1.00 10.65  ? 166 ARG A NH2 1 
ATOM 1149 N N   . GLN A 1 167 ? 280.828 311.717 124.377 1.00 10.77  ? 167 GLN A N   1 
ATOM 1150 C CA  . GLN A 1 167 ? 281.506 311.243 123.181 1.00 10.77  ? 167 GLN A CA  1 
ATOM 1151 C C   . GLN A 1 167 ? 280.967 311.909 121.925 1.00 10.77  ? 167 GLN A C   1 
ATOM 1152 O O   . GLN A 1 167 ? 281.735 312.206 121.009 1.00 10.77  ? 167 GLN A O   1 
ATOM 1153 C CB  . GLN A 1 167 ? 281.374 309.730 123.077 1.00 10.77  ? 167 GLN A CB  1 
ATOM 1154 C CG  . GLN A 1 167 ? 281.811 308.996 124.303 1.00 10.77  ? 167 GLN A CG  1 
ATOM 1155 C CD  . GLN A 1 167 ? 283.297 308.890 124.398 1.00 10.77  ? 167 GLN A CD  1 
ATOM 1156 O OE1 . GLN A 1 167 ? 283.985 308.849 123.387 1.00 10.77  ? 167 GLN A OE1 1 
ATOM 1157 N NE2 . GLN A 1 167 ? 283.811 308.850 125.615 1.00 10.77  ? 167 GLN A NE2 1 
ATOM 1158 N N   . ALA A 1 168 ? 279.658 312.153 121.858 1.00 10.61  ? 168 ALA A N   1 
ATOM 1159 C CA  . ALA A 1 168 ? 279.095 312.790 120.672 1.00 10.61  ? 168 ALA A CA  1 
ATOM 1160 C C   . ALA A 1 168 ? 279.504 314.246 120.578 1.00 10.61  ? 168 ALA A C   1 
ATOM 1161 O O   . ALA A 1 168 ? 279.780 314.740 119.475 1.00 10.61  ? 168 ALA A O   1 
ATOM 1162 C CB  . ALA A 1 168 ? 277.576 312.671 120.672 1.00 10.61  ? 168 ALA A CB  1 
ATOM 1163 N N   . ILE A 1 169 ? 279.593 314.928 121.725 1.00 11.00  ? 169 ILE A N   1 
ATOM 1164 C CA  . ILE A 1 169 ? 280.086 316.305 121.745 1.00 11.00  ? 169 ILE A CA  1 
ATOM 1165 C C   . ILE A 1 169 ? 281.541 316.363 121.295 1.00 11.00  ? 169 ILE A C   1 
ATOM 1166 O O   . ILE A 1 169 ? 281.920 317.200 120.466 1.00 11.00  ? 169 ILE A O   1 
ATOM 1167 C CB  . ILE A 1 169 ? 279.905 316.910 123.143 1.00 11.00  ? 169 ILE A CB  1 
ATOM 1168 C CG1 . ILE A 1 169 ? 278.432 317.107 123.429 1.00 11.00  ? 169 ILE A CG1 1 
ATOM 1169 C CG2 . ILE A 1 169 ? 280.583 318.228 123.226 1.00 11.00  ? 169 ILE A CG2 1 
ATOM 1170 C CD1 . ILE A 1 169 ? 278.149 317.371 124.839 1.00 11.00  ? 169 ILE A CD1 1 
ATOM 1171 N N   . LEU A 1 170 ? 282.367 315.438 121.792 1.00 11.19  ? 170 LEU A N   1 
ATOM 1172 C CA  . LEU A 1 170 ? 283.778 315.453 121.426 1.00 11.19  ? 170 LEU A CA  1 
ATOM 1173 C C   . LEU A 1 170 ? 284.009 315.029 119.983 1.00 11.19  ? 170 LEU A C   1 
ATOM 1174 O O   . LEU A 1 170 ? 284.922 315.541 119.333 1.00 11.19  ? 170 LEU A O   1 
ATOM 1175 C CB  . LEU A 1 170 ? 284.560 314.567 122.375 1.00 11.19  ? 170 LEU A CB  1 
ATOM 1176 C CG  . LEU A 1 170 ? 284.611 315.199 123.755 1.00 11.19  ? 170 LEU A CG  1 
ATOM 1177 C CD1 . LEU A 1 170 ? 285.004 314.182 124.777 1.00 11.19  ? 170 LEU A CD1 1 
ATOM 1178 C CD2 . LEU A 1 170 ? 285.576 316.342 123.736 1.00 11.19  ? 170 LEU A CD2 1 
ATOM 1179 N N   . ALA A 1 171 ? 283.188 314.122 119.458 1.00 12.11  ? 171 ALA A N   1 
ATOM 1180 C CA  . ALA A 1 171 ? 283.289 313.758 118.052 1.00 12.11  ? 171 ALA A CA  1 
ATOM 1181 C C   . ALA A 1 171 ? 282.869 314.902 117.150 1.00 12.11  ? 171 ALA A C   1 
ATOM 1182 O O   . ALA A 1 171 ? 283.452 315.091 116.075 1.00 12.11  ? 171 ALA A O   1 
ATOM 1183 C CB  . ALA A 1 171 ? 282.444 312.525 117.764 1.00 12.11  ? 171 ALA A CB  1 
ATOM 1184 N N   . TRP A 1 172 ? 281.885 315.691 117.573 1.00 15.85  ? 172 TRP A N   1 
ATOM 1185 C CA  . TRP A 1 172 ? 281.598 316.905 116.825 1.00 15.85  ? 172 TRP A CA  1 
ATOM 1186 C C   . TRP A 1 172 ? 282.741 317.904 116.925 1.00 15.85  ? 172 TRP A C   1 
ATOM 1187 O O   . TRP A 1 172 ? 283.001 318.638 115.967 1.00 15.85  ? 172 TRP A O   1 
ATOM 1188 C CB  . TRP A 1 172 ? 280.297 317.542 117.301 1.00 15.85  ? 172 TRP A CB  1 
ATOM 1189 C CG  . TRP A 1 172 ? 279.955 318.736 116.503 1.00 15.85  ? 172 TRP A CG  1 
ATOM 1190 C CD1 . TRP A 1 172 ? 279.964 320.020 116.925 1.00 15.85  ? 172 TRP A CD1 1 
ATOM 1191 C CD2 . TRP A 1 172 ? 279.595 318.768 115.123 1.00 15.85  ? 172 TRP A CD2 1 
ATOM 1192 N NE1 . TRP A 1 172 ? 279.618 320.856 115.902 1.00 15.85  ? 172 TRP A NE1 1 
ATOM 1193 C CE2 . TRP A 1 172 ? 279.386 320.106 114.782 1.00 15.85  ? 172 TRP A CE2 1 
ATOM 1194 C CE3 . TRP A 1 172 ? 279.418 317.792 114.144 1.00 15.85  ? 172 TRP A CE3 1 
ATOM 1195 C CZ2 . TRP A 1 172 ? 279.015 320.493 113.512 1.00 15.85  ? 172 TRP A CZ2 1 
ATOM 1196 C CZ3 . TRP A 1 172 ? 279.054 318.179 112.890 1.00 15.85  ? 172 TRP A CZ3 1 
ATOM 1197 C CH2 . TRP A 1 172 ? 278.857 319.513 112.581 1.00 15.85  ? 172 TRP A CH2 1 
ATOM 1198 N N   . GLY A 1 173 ? 283.441 317.931 118.057 1.00 20.03  ? 173 GLY A N   1 
ATOM 1199 C CA  . GLY A 1 173 ? 284.612 318.785 118.171 1.00 20.03  ? 173 GLY A CA  1 
ATOM 1200 C C   . GLY A 1 173 ? 285.723 318.397 117.213 1.00 20.03  ? 173 GLY A C   1 
ATOM 1201 O O   . GLY A 1 173 ? 286.364 319.260 116.608 1.00 20.03  ? 173 GLY A O   1 
ATOM 1202 N N   . GLU A 1 174 ? 285.949 317.092 117.046 1.00 21.81  ? 174 GLU A N   1 
ATOM 1203 C CA  . GLU A 1 174 ? 286.943 316.635 116.078 1.00 21.81  ? 174 GLU A CA  1 
ATOM 1204 C C   . GLU A 1 174 ? 286.508 316.926 114.651 1.00 21.81  ? 174 GLU A C   1 
ATOM 1205 O O   . GLU A 1 174 ? 287.339 317.270 113.803 1.00 21.81  ? 174 GLU A O   1 
ATOM 1206 C CB  . GLU A 1 174 ? 287.217 315.146 116.233 1.00 21.81  ? 174 GLU A CB  1 
ATOM 1207 C CG  . GLU A 1 174 ? 287.549 314.686 117.632 1.00 21.81  ? 174 GLU A CG  1 
ATOM 1208 C CD  . GLU A 1 174 ? 288.710 315.425 118.253 1.00 21.81  ? 174 GLU A CD  1 
ATOM 1209 O OE1 . GLU A 1 174 ? 289.704 315.690 117.546 1.00 21.81  ? 174 GLU A OE1 1 
ATOM 1210 O OE2 . GLU A 1 174 ? 288.631 315.730 119.461 1.00 21.81  ? 174 GLU A OE2 1 
ATOM 1211 N N   . LEU A 1 175 ? 285.213 316.803 114.366 1.00 22.30  ? 175 LEU A N   1 
ATOM 1212 C CA  . LEU A 1 175 ? 284.726 317.147 113.034 1.00 22.30  ? 175 LEU A CA  1 
ATOM 1213 C C   . LEU A 1 175 ? 284.884 318.631 112.746 1.00 22.30  ? 175 LEU A C   1 
ATOM 1214 O O   . LEU A 1 175 ? 285.251 319.019 111.632 1.00 22.30  ? 175 LEU A O   1 
ATOM 1215 C CB  . LEU A 1 175 ? 283.272 316.731 112.895 1.00 22.30  ? 175 LEU A CB  1 
ATOM 1216 C CG  . LEU A 1 175 ? 283.068 315.246 112.678 1.00 22.30  ? 175 LEU A CG  1 
ATOM 1217 C CD1 . LEU A 1 175 ? 281.601 315.001 112.503 1.00 22.30  ? 175 LEU A CD1 1 
ATOM 1218 C CD2 . LEU A 1 175 ? 283.835 314.824 111.455 1.00 22.30  ? 175 LEU A CD2 1 
ATOM 1219 N N   . MET A 1 176 ? 284.659 319.475 113.750 1.00 30.59  ? 176 MET A N   1 
ATOM 1220 C CA  . MET A 1 176 ? 284.834 320.906 113.543 1.00 30.59  ? 176 MET A CA  1 
ATOM 1221 C C   . MET A 1 176 ? 286.301 321.295 113.421 1.00 30.59  ? 176 MET A C   1 
ATOM 1222 O O   . MET A 1 176 ? 286.627 322.219 112.663 1.00 30.59  ? 176 MET A O   1 
ATOM 1223 C CB  . MET A 1 176 ? 284.163 321.690 114.663 1.00 30.59  ? 176 MET A CB  1 
ATOM 1224 C CG  . MET A 1 176 ? 282.666 321.640 114.579 1.00 30.59  ? 176 MET A CG  1 
ATOM 1225 S SD  . MET A 1 176 ? 282.116 322.223 112.968 1.00 30.59  ? 176 MET A SD  1 
ATOM 1226 C CE  . MET A 1 176 ? 282.537 323.955 113.071 1.00 30.59  ? 176 MET A CE  1 
ATOM 1227 N N   . THR A 1 177 ? 287.203 320.604 114.124 1.00 29.12  ? 177 THR A N   1 
ATOM 1228 C CA  . THR A 1 177 ? 288.604 320.948 113.924 1.00 29.12  ? 177 THR A CA  1 
ATOM 1229 C C   . THR A 1 177 ? 289.124 320.423 112.590 1.00 29.12  ? 177 THR A C   1 
ATOM 1230 O O   . THR A 1 177 ? 290.004 321.049 111.998 1.00 29.12  ? 177 THR A O   1 
ATOM 1231 C CB  . THR A 1 177 ? 289.479 320.492 115.099 1.00 29.12  ? 177 THR A CB  1 
ATOM 1232 O OG1 . THR A 1 177 ? 290.730 321.181 115.037 1.00 29.12  ? 177 THR A OG1 1 
ATOM 1233 C CG2 . THR A 1 177 ? 289.771 319.023 115.078 1.00 29.12  ? 177 THR A CG2 1 
ATOM 1234 N N   . LEU A 1 178 ? 288.535 319.354 112.049 1.00 28.99  ? 178 LEU A N   1 
ATOM 1235 C CA  . LEU A 1 178 ? 288.874 318.969 110.685 1.00 28.99  ? 178 LEU A CA  1 
ATOM 1236 C C   . LEU A 1 178 ? 288.326 319.963 109.675 1.00 28.99  ? 178 LEU A C   1 
ATOM 1237 O O   . LEU A 1 178 ? 288.970 320.222 108.651 1.00 28.99  ? 178 LEU A O   1 
ATOM 1238 C CB  . LEU A 1 178 ? 288.354 317.568 110.398 1.00 28.99  ? 178 LEU A CB  1 
ATOM 1239 C CG  . LEU A 1 178 ? 288.100 317.051 108.987 1.00 28.99  ? 178 LEU A CG  1 
ATOM 1240 C CD1 . LEU A 1 178 ? 289.353 316.983 108.151 1.00 28.99  ? 178 LEU A CD1 1 
ATOM 1241 C CD2 . LEU A 1 178 ? 287.540 315.682 109.147 1.00 28.99  ? 178 LEU A CD2 1 
ATOM 1242 N N   . ALA A 1 179 ? 287.157 320.541 109.958 1.00 32.53  ? 179 ALA A N   1 
ATOM 1243 C CA  . ALA A 1 179 ? 286.593 321.562 109.080 1.00 32.53  ? 179 ALA A CA  1 
ATOM 1244 C C   . ALA A 1 179 ? 287.468 322.810 109.046 1.00 32.53  ? 179 ALA A C   1 
ATOM 1245 O O   . ALA A 1 179 ? 287.793 323.326 107.970 1.00 32.53  ? 179 ALA A O   1 
ATOM 1246 C CB  . ALA A 1 179 ? 285.180 321.910 109.535 1.00 32.53  ? 179 ALA A CB  1 
ATOM 1247 N N   . THR A 1 180 ? 287.889 323.294 110.215 1.00 39.07  ? 180 THR A N   1 
ATOM 1248 C CA  . THR A 1 180 ? 288.758 324.465 110.210 1.00 39.07  ? 180 THR A CA  1 
ATOM 1249 C C   . THR A 1 180 ? 290.180 324.129 109.779 1.00 39.07  ? 180 THR A C   1 
ATOM 1250 O O   . THR A 1 180 ? 290.927 325.042 109.417 1.00 39.07  ? 180 THR A O   1 
ATOM 1251 C CB  . THR A 1 180 ? 288.790 325.157 111.576 1.00 39.07  ? 180 THR A CB  1 
ATOM 1252 O OG1 . THR A 1 180 ? 289.585 326.342 111.482 1.00 39.07  ? 180 THR A OG1 1 
ATOM 1253 C CG2 . THR A 1 180 ? 289.418 324.284 112.612 1.00 39.07  ? 180 THR A CG2 1 
ATOM 1254 N N   . TRP A 1 181 ? 290.574 322.854 109.795 1.00 45.48  ? 181 TRP A N   1 
ATOM 1255 C CA  . TRP A 1 181 ? 291.864 322.495 109.222 1.00 45.48  ? 181 TRP A CA  1 
ATOM 1256 C C   . TRP A 1 181 ? 291.815 322.546 107.704 1.00 45.48  ? 181 TRP A C   1 
ATOM 1257 O O   . TRP A 1 181 ? 292.699 323.127 107.069 1.00 45.48  ? 181 TRP A O   1 
ATOM 1258 C CB  . TRP A 1 181 ? 292.295 321.110 109.692 1.00 45.48  ? 181 TRP A CB  1 
ATOM 1259 C CG  . TRP A 1 181 ? 293.618 320.696 109.140 1.00 45.48  ? 181 TRP A CG  1 
ATOM 1260 C CD1 . TRP A 1 181 ? 294.838 320.959 109.672 1.00 45.48  ? 181 TRP A CD1 1 
ATOM 1261 C CD2 . TRP A 1 181 ? 293.856 319.944 107.946 1.00 45.48  ? 181 TRP A CD2 1 
ATOM 1262 N NE1 . TRP A 1 181 ? 295.824 320.422 108.886 1.00 45.48  ? 181 TRP A NE1 1 
ATOM 1263 C CE2 . TRP A 1 181 ? 295.245 319.794 107.819 1.00 45.48  ? 181 TRP A CE2 1 
ATOM 1264 C CE3 . TRP A 1 181 ? 293.028 319.389 106.971 1.00 45.48  ? 181 TRP A CE3 1 
ATOM 1265 C CZ2 . TRP A 1 181 ? 295.824 319.110 106.762 1.00 45.48  ? 181 TRP A CZ2 1 
ATOM 1266 C CZ3 . TRP A 1 181 ? 293.606 318.712 105.923 1.00 45.48  ? 181 TRP A CZ3 1 
ATOM 1267 C CH2 . TRP A 1 181 ? 294.989 318.577 105.826 1.00 45.48  ? 181 TRP A CH2 1 
ATOM 1268 N N   . VAL A 1 182 ? 290.788 321.941 107.101 1.00 41.58  ? 182 VAL A N   1 
ATOM 1269 C CA  . VAL A 1 182 ? 290.718 321.925 105.647 1.00 41.58  ? 182 VAL A CA  1 
ATOM 1270 C C   . VAL A 1 182 ? 290.354 323.304 105.111 1.00 41.58  ? 182 VAL A C   1 
ATOM 1271 O O   . VAL A 1 182 ? 290.665 323.625 103.960 1.00 41.58  ? 182 VAL A O   1 
ATOM 1272 C CB  . VAL A 1 182 ? 289.737 320.834 105.171 1.00 41.58  ? 182 VAL A CB  1 
ATOM 1273 C CG1 . VAL A 1 182 ? 288.309 321.180 105.525 1.00 41.58  ? 182 VAL A CG1 1 
ATOM 1274 C CG2 . VAL A 1 182 ? 289.906 320.531 103.688 1.00 41.58  ? 182 VAL A CG2 1 
ATOM 1275 N N   . GLY A 1 183 ? 289.774 324.168 105.942 1.00 44.33  ? 183 GLY A N   1 
ATOM 1276 C CA  . GLY A 1 183 ? 289.628 325.549 105.542 1.00 44.33  ? 183 GLY A CA  1 
ATOM 1277 C C   . GLY A 1 183 ? 290.869 326.404 105.666 1.00 44.33  ? 183 GLY A C   1 
ATOM 1278 O O   . GLY A 1 183 ? 290.767 327.629 105.580 1.00 44.33  ? 183 GLY A O   1 
ATOM 1279 N N   . ASN A 1 184 ? 292.042 325.807 105.872 1.00 52.38  ? 184 ASN A N   1 
ATOM 1280 C CA  . ASN A 1 184 ? 293.285 326.552 105.984 1.00 52.38  ? 184 ASN A CA  1 
ATOM 1281 C C   . ASN A 1 184 ? 294.308 326.185 104.921 1.00 52.38  ? 184 ASN A C   1 
ATOM 1282 O O   . ASN A 1 184 ? 295.246 326.957 104.698 1.00 52.38  ? 184 ASN A O   1 
ATOM 1283 C CB  . ASN A 1 184 ? 293.906 326.355 107.373 1.00 52.38  ? 184 ASN A CB  1 
ATOM 1284 C CG  . ASN A 1 184 ? 293.164 327.113 108.446 1.00 52.38  ? 184 ASN A CG  1 
ATOM 1285 O OD1 . ASN A 1 184 ? 292.305 327.938 108.150 1.00 52.38  ? 184 ASN A OD1 1 
ATOM 1286 N ND2 . ASN A 1 184 ? 293.497 326.848 109.700 1.00 52.38  ? 184 ASN A ND2 1 
ATOM 1287 N N   . ASN A 1 185 ? 294.160 325.042 104.258 1.00 56.49  ? 185 ASN A N   1 
ATOM 1288 C CA  . ASN A 1 185 ? 295.130 324.635 103.252 1.00 56.49  ? 185 ASN A CA  1 
ATOM 1289 C C   . ASN A 1 185 ? 294.454 323.791 102.179 1.00 56.49  ? 185 ASN A C   1 
ATOM 1290 O O   . ASN A 1 185 ? 293.570 322.980 102.464 1.00 56.49  ? 185 ASN A O   1 
ATOM 1291 C CB  . ASN A 1 185 ? 296.312 323.903 103.899 1.00 56.49  ? 185 ASN A CB  1 
ATOM 1292 C CG  . ASN A 1 185 ? 295.882 322.834 104.878 1.00 56.49  ? 185 ASN A CG  1 
ATOM 1293 O OD1 . ASN A 1 185 ? 294.700 322.566 105.045 1.00 56.49  ? 185 ASN A OD1 1 
ATOM 1294 N ND2 . ASN A 1 185 ? 296.852 322.229 105.546 1.00 56.49  ? 185 ASN A ND2 1 
ATOM 1295 N N   . LEU A 1 186 ? 294.869 324.013 100.938 1.00 60.40  ? 186 LEU A N   1 
ATOM 1296 C CA  . LEU A 1 186 ? 294.259 323.346 99.795  1.00 60.40  ? 186 LEU A CA  1 
ATOM 1297 C C   . LEU A 1 186 ? 295.315 322.975 98.763  1.00 60.40  ? 186 LEU A C   1 
ATOM 1298 O O   . LEU A 1 186 ? 296.391 323.568 98.727  1.00 60.40  ? 186 LEU A O   1 
ATOM 1299 C CB  . LEU A 1 186 ? 293.184 324.233 99.148  1.00 60.40  ? 186 LEU A CB  1 
ATOM 1300 C CG  . LEU A 1 186 ? 293.564 325.421 98.252  1.00 60.40  ? 186 LEU A CG  1 
ATOM 1301 C CD1 . LEU A 1 186 ? 292.379 325.810 97.385  1.00 60.40  ? 186 LEU A CD1 1 
ATOM 1302 C CD2 . LEU A 1 186 ? 294.035 326.636 99.043  1.00 60.40  ? 186 LEU A CD2 1 
ATOM 1303 N N   . ASP A 1 198 ? 286.993 323.886 100.600 1.00 59.48  ? 198 ASP A N   1 
ATOM 1304 C CA  . ASP A 1 198 ? 286.175 323.988 99.397  1.00 59.48  ? 198 ASP A CA  1 
ATOM 1305 C C   . ASP A 1 198 ? 284.719 323.634 99.694  1.00 59.48  ? 198 ASP A C   1 
ATOM 1306 O O   . ASP A 1 198 ? 283.981 324.431 100.271 1.00 59.48  ? 198 ASP A O   1 
ATOM 1307 C CB  . ASP A 1 198 ? 286.730 323.082 98.297  1.00 59.48  ? 198 ASP A CB  1 
ATOM 1308 C CG  . ASP A 1 198 ? 286.486 323.636 96.908  1.00 59.48  ? 198 ASP A CG  1 
ATOM 1309 O OD1 . ASP A 1 198 ? 285.509 324.389 96.725  1.00 59.48  ? 198 ASP A OD1 1 
ATOM 1310 O OD2 . ASP A 1 198 ? 287.275 323.317 95.997  1.00 59.48  ? 198 ASP A OD2 1 
ATOM 1311 N N   . LEU A 1 199 ? 284.308 322.434 99.283  1.00 48.96  ? 199 LEU A N   1 
ATOM 1312 C CA  . LEU A 1 199 ? 282.963 321.943 99.545  1.00 48.96  ? 199 LEU A CA  1 
ATOM 1313 C C   . LEU A 1 199 ? 282.964 320.748 100.483 1.00 48.96  ? 199 LEU A C   1 
ATOM 1314 O O   . LEU A 1 199 ? 281.899 320.194 100.767 1.00 48.96  ? 199 LEU A O   1 
ATOM 1315 C CB  . LEU A 1 199 ? 282.248 321.598 98.232  1.00 48.96  ? 199 LEU A CB  1 
ATOM 1316 C CG  . LEU A 1 199 ? 282.781 320.518 97.281  1.00 48.96  ? 199 LEU A CG  1 
ATOM 1317 C CD1 . LEU A 1 199 ? 282.185 319.132 97.532  1.00 48.96  ? 199 LEU A CD1 1 
ATOM 1318 C CD2 . LEU A 1 199 ? 282.559 320.942 95.840  1.00 48.96  ? 199 LEU A CD2 1 
ATOM 1319 N N   . VAL A 1 200 ? 284.131 320.326 100.964 1.00 43.21  ? 200 VAL A N   1 
ATOM 1320 C CA  . VAL A 1 200 ? 284.161 319.274 101.968 1.00 43.21  ? 200 VAL A CA  1 
ATOM 1321 C C   . VAL A 1 200 ? 283.831 319.837 103.343 1.00 43.21  ? 200 VAL A C   1 
ATOM 1322 O O   . VAL A 1 200 ? 283.531 319.074 104.267 1.00 43.21  ? 200 VAL A O   1 
ATOM 1323 C CB  . VAL A 1 200 ? 285.523 318.554 101.952 1.00 43.21  ? 200 VAL A CB  1 
ATOM 1324 C CG1 . VAL A 1 200 ? 286.559 319.331 102.715 1.00 43.21  ? 200 VAL A CG1 1 
ATOM 1325 C CG2 . VAL A 1 200 ? 285.411 317.133 102.477 1.00 43.21  ? 200 VAL A CG2 1 
ATOM 1326 N N   . VAL A 1 201 ? 283.866 321.161 103.502 1.00 42.46  ? 201 VAL A N   1 
ATOM 1327 C CA  . VAL A 1 201 ? 283.503 321.759 104.778 1.00 42.46  ? 201 VAL A CA  1 
ATOM 1328 C C   . VAL A 1 201 ? 281.996 321.659 105.006 1.00 42.46  ? 201 VAL A C   1 
ATOM 1329 O O   . VAL A 1 201 ? 281.542 321.474 106.142 1.00 42.46  ? 201 VAL A O   1 
ATOM 1330 C CB  . VAL A 1 201 ? 284.042 323.206 104.836 1.00 42.46  ? 201 VAL A CB  1 
ATOM 1331 C CG1 . VAL A 1 201 ? 283.611 324.010 103.612 1.00 42.46  ? 201 VAL A CG1 1 
ATOM 1332 C CG2 . VAL A 1 201 ? 283.655 323.910 106.137 1.00 42.46  ? 201 VAL A CG2 1 
ATOM 1333 N N   . ASN A 1 202 ? 281.197 321.713 103.944 1.00 40.17  ? 202 ASN A N   1 
ATOM 1334 C CA  . ASN A 1 202 ? 279.766 321.504 104.075 1.00 40.17  ? 202 ASN A CA  1 
ATOM 1335 C C   . ASN A 1 202 ? 279.353 320.092 103.703 1.00 40.17  ? 202 ASN A C   1 
ATOM 1336 O O   . ASN A 1 202 ? 278.159 319.825 103.563 1.00 40.17  ? 202 ASN A O   1 
ATOM 1337 C CB  . ASN A 1 202 ? 278.982 322.509 103.235 1.00 40.17  ? 202 ASN A CB  1 
ATOM 1338 C CG  . ASN A 1 202 ? 279.073 322.226 101.763 1.00 40.17  ? 202 ASN A CG  1 
ATOM 1339 O OD1 . ASN A 1 202 ? 280.110 322.443 101.148 1.00 40.17  ? 202 ASN A OD1 1 
ATOM 1340 N ND2 . ASN A 1 202 ? 277.994 321.710 101.191 1.00 40.17  ? 202 ASN A ND2 1 
ATOM 1341 N N   . TYR A 1 203 ? 280.309 319.186 103.516 1.00 35.51  ? 203 TYR A N   1 
ATOM 1342 C CA  . TYR A 1 203 ? 279.948 317.778 103.548 1.00 35.51  ? 203 TYR A CA  1 
ATOM 1343 C C   . TYR A 1 203 ? 279.830 317.304 104.984 1.00 35.51  ? 203 TYR A C   1 
ATOM 1344 O O   . TYR A 1 203 ? 278.956 316.491 105.298 1.00 35.51  ? 203 TYR A O   1 
ATOM 1345 C CB  . TYR A 1 203 ? 280.971 316.928 102.793 1.00 35.51  ? 203 TYR A CB  1 
ATOM 1346 C CG  . TYR A 1 203 ? 280.707 315.444 102.908 1.00 35.51  ? 203 TYR A CG  1 
ATOM 1347 C CD1 . TYR A 1 203 ? 279.711 314.844 102.161 1.00 35.51  ? 203 TYR A CD1 1 
ATOM 1348 C CD2 . TYR A 1 203 ? 281.447 314.646 103.769 1.00 35.51  ? 203 TYR A CD2 1 
ATOM 1349 C CE1 . TYR A 1 203 ? 279.461 313.491 102.267 1.00 35.51  ? 203 TYR A CE1 1 
ATOM 1350 C CE2 . TYR A 1 203 ? 281.196 313.299 103.890 1.00 35.51  ? 203 TYR A CE2 1 
ATOM 1351 C CZ  . TYR A 1 203 ? 280.206 312.729 103.135 1.00 35.51  ? 203 TYR A CZ  1 
ATOM 1352 O OH  . TYR A 1 203 ? 279.964 311.385 103.250 1.00 35.51  ? 203 TYR A OH  1 
ATOM 1353 N N   . VAL A 1 204 ? 280.707 317.806 105.856 1.00 36.09  ? 204 VAL A N   1 
ATOM 1354 C CA  . VAL A 1 204 ? 280.693 317.422 107.264 1.00 36.09  ? 204 VAL A CA  1 
ATOM 1355 C C   . VAL A 1 204 ? 279.401 317.877 107.921 1.00 36.09  ? 204 VAL A C   1 
ATOM 1356 O O   . VAL A 1 204 ? 278.578 317.047 108.321 1.00 36.09  ? 204 VAL A O   1 
ATOM 1357 C CB  . VAL A 1 204 ? 281.917 317.998 107.992 1.00 36.09  ? 204 VAL A CB  1 
ATOM 1358 C CG1 . VAL A 1 204 ? 281.987 317.453 109.392 1.00 36.09  ? 204 VAL A CG1 1 
ATOM 1359 C CG2 . VAL A 1 204 ? 283.181 317.668 107.241 1.00 36.09  ? 204 VAL A CG2 1 
ATOM 1360 N N   . ASN A 1 205 ? 279.168 319.198 107.928 1.00 38.55  ? 205 ASN A N   1 
ATOM 1361 C CA  . ASN A 1 205 ? 278.062 319.830 108.646 1.00 38.55  ? 205 ASN A CA  1 
ATOM 1362 C C   . ASN A 1 205 ? 276.692 319.362 108.185 1.00 38.55  ? 205 ASN A C   1 
ATOM 1363 O O   . ASN A 1 205 ? 275.736 319.456 108.958 1.00 38.55  ? 205 ASN A O   1 
ATOM 1364 C CB  . ASN A 1 205 ? 278.130 321.350 108.498 1.00 38.55  ? 205 ASN A CB  1 
ATOM 1365 C CG  . ASN A 1 205 ? 279.537 321.889 108.611 1.00 38.55  ? 205 ASN A CG  1 
ATOM 1366 O OD1 . ASN A 1 205 ? 280.227 321.654 109.599 1.00 38.55  ? 205 ASN A OD1 1 
ATOM 1367 N ND2 . ASN A 1 205 ? 279.971 322.623 107.596 1.00 38.55  ? 205 ASN A ND2 1 
ATOM 1368 N N   . THR A 1 206 ? 276.562 318.867 106.957 1.00 33.39  ? 206 THR A N   1 
ATOM 1369 C CA  . THR A 1 206 ? 275.303 318.245 106.583 1.00 33.39  ? 206 THR A CA  1 
ATOM 1370 C C   . THR A 1 206 ? 275.336 316.739 106.785 1.00 33.39  ? 206 THR A C   1 
ATOM 1371 O O   . THR A 1 206 ? 274.659 316.220 107.678 1.00 33.39  ? 206 THR A O   1 
ATOM 1372 C CB  . THR A 1 206 ? 274.958 318.562 105.135 1.00 33.39  ? 206 THR A CB  1 
ATOM 1373 O OG1 . THR A 1 206 ? 275.805 317.802 104.271 1.00 33.39  ? 206 THR A OG1 1 
ATOM 1374 C CG2 . THR A 1 206 ? 275.151 320.034 104.868 1.00 33.39  ? 206 THR A CG2 1 
ATOM 1375 N N   . ASN A 1 207 ? 276.179 316.038 106.029 1.00 31.70  ? 207 ASN A N   1 
ATOM 1376 C CA  . ASN A 1 207 ? 276.055 314.590 105.940 1.00 31.70  ? 207 ASN A CA  1 
ATOM 1377 C C   . ASN A 1 207 ? 276.608 313.861 107.149 1.00 31.70  ? 207 ASN A C   1 
ATOM 1378 O O   . ASN A 1 207 ? 276.017 312.863 107.565 1.00 31.70  ? 207 ASN A O   1 
ATOM 1379 C CB  . ASN A 1 207 ? 276.738 314.079 104.681 1.00 31.70  ? 207 ASN A CB  1 
ATOM 1380 C CG  . ASN A 1 207 ? 275.868 314.225 103.466 1.00 31.70  ? 207 ASN A CG  1 
ATOM 1381 O OD1 . ASN A 1 207 ? 274.709 313.822 103.475 1.00 31.70  ? 207 ASN A OD1 1 
ATOM 1382 N ND2 . ASN A 1 207 ? 276.409 314.824 102.414 1.00 31.70  ? 207 ASN A ND2 1 
ATOM 1383 N N   . MET A 1 208 ? 277.724 314.307 107.716 1.00 29.06  ? 208 MET A N   1 
ATOM 1384 C CA  . MET A 1 208 ? 278.192 313.722 108.952 1.00 29.06  ? 208 MET A CA  1 
ATOM 1385 C C   . MET A 1 208 ? 277.582 314.394 110.161 1.00 29.06  ? 208 MET A C   1 
ATOM 1386 O O   . MET A 1 208 ? 277.617 313.820 111.250 1.00 29.06  ? 208 MET A O   1 
ATOM 1387 C CB  . MET A 1 208 ? 279.716 313.829 109.051 1.00 29.06  ? 208 MET A CB  1 
ATOM 1388 C CG  . MET A 1 208 ? 280.469 313.135 107.947 1.00 29.06  ? 208 MET A CG  1 
ATOM 1389 S SD  . MET A 1 208 ? 282.181 313.045 108.429 1.00 29.06  ? 208 MET A SD  1 
ATOM 1390 C CE  . MET A 1 208 ? 281.981 312.040 109.882 1.00 29.06  ? 208 MET A CE  1 
ATOM 1391 N N   . GLY A 1 209 ? 277.041 315.599 109.992 1.00 22.83  ? 209 GLY A N   1 
ATOM 1392 C CA  . GLY A 1 209 ? 276.382 316.285 111.081 1.00 22.83  ? 209 GLY A CA  1 
ATOM 1393 C C   . GLY A 1 209 ? 274.988 315.784 111.351 1.00 22.83  ? 209 GLY A C   1 
ATOM 1394 O O   . GLY A 1 209 ? 274.462 316.022 112.439 1.00 22.83  ? 209 GLY A O   1 
ATOM 1395 N N   . LEU A 1 210 ? 274.382 315.092 110.384 1.00 15.96  ? 210 LEU A N   1 
ATOM 1396 C CA  . LEU A 1 210 ? 273.048 314.537 110.579 1.00 15.96  ? 210 LEU A CA  1 
ATOM 1397 C C   . LEU A 1 210 ? 273.033 313.483 111.678 1.00 15.96  ? 210 LEU A C   1 
ATOM 1398 O O   . LEU A 1 210 ? 272.161 313.508 112.551 1.00 15.96  ? 210 LEU A O   1 
ATOM 1399 C CB  . LEU A 1 210 ? 272.538 313.959 109.266 1.00 15.96  ? 210 LEU A CB  1 
ATOM 1400 C CG  . LEU A 1 210 ? 271.140 313.350 109.205 1.00 15.96  ? 210 LEU A CG  1 
ATOM 1401 C CD1 . LEU A 1 210 ? 270.107 314.174 109.940 1.00 15.96  ? 210 LEU A CD1 1 
ATOM 1402 C CD2 . LEU A 1 210 ? 270.739 313.208 107.761 1.00 15.96  ? 210 LEU A CD2 1 
ATOM 1403 N N   . LYS A 1 211 ? 273.993 312.558 111.664 1.00 13.88  ? 211 LYS A N   1 
ATOM 1404 C CA  . LYS A 1 211 ? 274.032 311.527 112.695 1.00 13.88  ? 211 LYS A CA  1 
ATOM 1405 C C   . LYS A 1 211 ? 274.431 312.094 114.046 1.00 13.88  ? 211 LYS A C   1 
ATOM 1406 O O   . LYS A 1 211 ? 274.003 311.581 115.087 1.00 13.88  ? 211 LYS A O   1 
ATOM 1407 C CB  . LYS A 1 211 ? 274.995 310.427 112.294 1.00 13.88  ? 211 LYS A CB  1 
ATOM 1408 C CG  . LYS A 1 211 ? 274.770 309.910 110.904 1.00 13.88  ? 211 LYS A CG  1 
ATOM 1409 C CD  . LYS A 1 211 ? 275.072 308.434 110.865 1.00 13.88  ? 211 LYS A CD  1 
ATOM 1410 C CE  . LYS A 1 211 ? 274.832 307.842 109.503 1.00 13.88  ? 211 LYS A CE  1 
ATOM 1411 N NZ  . LYS A 1 211 ? 275.527 306.532 109.389 1.00 13.88  ? 211 LYS A NZ  1 
ATOM 1412 N N   . ILE A 1 212 ? 275.218 313.166 114.048 1.00 13.98  ? 212 ILE A N   1 
ATOM 1413 C CA  . ILE A 1 212 ? 275.524 313.868 115.286 1.00 13.98  ? 212 ILE A CA  1 
ATOM 1414 C C   . ILE A 1 212 ? 274.269 314.513 115.845 1.00 13.98  ? 212 ILE A C   1 
ATOM 1415 O O   . ILE A 1 212 ? 274.014 314.453 117.049 1.00 13.98  ? 212 ILE A O   1 
ATOM 1416 C CB  . ILE A 1 212 ? 276.641 314.892 115.035 1.00 13.98  ? 212 ILE A CB  1 
ATOM 1417 C CG1 . ILE A 1 212 ? 277.960 314.175 114.774 1.00 13.98  ? 212 ILE A CG1 1 
ATOM 1418 C CG2 . ILE A 1 212 ? 276.813 315.805 116.201 1.00 13.98  ? 212 ILE A CG2 1 
ATOM 1419 C CD1 . ILE A 1 212 ? 278.437 313.360 115.927 1.00 13.98  ? 212 ILE A CD1 1 
ATOM 1420 N N   . ARG A 1 213 ? 273.441 315.090 114.970 1.00 18.06  ? 213 ARG A N   1 
ATOM 1421 C CA  . ARG A 1 213 ? 272.179 315.691 115.388 1.00 18.06  ? 213 ARG A CA  1 
ATOM 1422 C C   . ARG A 1 213 ? 271.217 314.649 115.927 1.00 18.06  ? 213 ARG A C   1 
ATOM 1423 O O   . ARG A 1 213 ? 270.514 314.901 116.907 1.00 18.06  ? 213 ARG A O   1 
ATOM 1424 C CB  . ARG A 1 213 ? 271.551 316.433 114.220 1.00 18.06  ? 213 ARG A CB  1 
ATOM 1425 C CG  . ARG A 1 213 ? 271.967 317.855 114.131 1.00 18.06  ? 213 ARG A CG  1 
ATOM 1426 C CD  . ARG A 1 213 ? 271.749 318.404 112.763 1.00 18.06  ? 213 ARG A CD  1 
ATOM 1427 N NE  . ARG A 1 213 ? 270.397 318.153 112.313 1.00 18.06  ? 213 ARG A NE  1 
ATOM 1428 C CZ  . ARG A 1 213 ? 270.025 318.176 111.044 1.00 18.06  ? 213 ARG A CZ  1 
ATOM 1429 N NH1 . ARG A 1 213 ? 270.911 318.438 110.102 1.00 18.06  ? 213 ARG A NH1 1 
ATOM 1430 N NH2 . ARG A 1 213 ? 268.771 317.930 110.717 1.00 18.06  ? 213 ARG A NH2 1 
ATOM 1431 N N   . GLN A 1 214 ? 271.195 313.467 115.316 1.00 19.11  ? 214 GLN A N   1 
ATOM 1432 C CA  . GLN A 1 214 ? 270.349 312.382 115.802 1.00 19.11  ? 214 GLN A CA  1 
ATOM 1433 C C   . GLN A 1 214 ? 270.786 311.896 117.172 1.00 19.11  ? 214 GLN A C   1 
ATOM 1434 O O   . GLN A 1 214 ? 269.949 311.699 118.060 1.00 19.11  ? 214 GLN A O   1 
ATOM 1435 C CB  . GLN A 1 214 ? 270.359 311.228 114.811 1.00 19.11  ? 214 GLN A CB  1 
ATOM 1436 C CG  . GLN A 1 214 ? 269.772 311.589 113.483 1.00 19.11  ? 214 GLN A CG  1 
ATOM 1437 C CD  . GLN A 1 214 ? 269.309 310.402 112.712 1.00 19.11  ? 214 GLN A CD  1 
ATOM 1438 O OE1 . GLN A 1 214 ? 268.830 309.434 113.284 1.00 19.11  ? 214 GLN A OE1 1 
ATOM 1439 N NE2 . GLN A 1 214 ? 269.442 310.464 111.398 1.00 19.11  ? 214 GLN A NE2 1 
ATOM 1440 N N   . LEU A 1 215 ? 272.094 311.718 117.366 1.00 13.28  ? 215 LEU A N   1 
ATOM 1441 C CA  . LEU A 1 215 ? 272.617 311.273 118.654 1.00 13.28  ? 215 LEU A CA  1 
ATOM 1442 C C   . LEU A 1 215 ? 272.403 312.315 119.737 1.00 13.28  ? 215 LEU A C   1 
ATOM 1443 O O   . LEU A 1 215 ? 272.025 311.979 120.868 1.00 13.28  ? 215 LEU A O   1 
ATOM 1444 C CB  . LEU A 1 215 ? 274.103 310.980 118.538 1.00 13.28  ? 215 LEU A CB  1 
ATOM 1445 C CG  . LEU A 1 215 ? 274.544 309.659 117.958 1.00 13.28  ? 215 LEU A CG  1 
ATOM 1446 C CD1 . LEU A 1 215 ? 275.858 309.887 117.284 1.00 13.28  ? 215 LEU A CD1 1 
ATOM 1447 C CD2 . LEU A 1 215 ? 274.680 308.666 119.070 1.00 13.28  ? 215 LEU A CD2 1 
ATOM 1448 N N   . LEU A 1 216 ? 272.640 313.582 119.403 1.00 16.83  ? 216 LEU A N   1 
ATOM 1449 C CA  . LEU A 1 216 ? 272.478 314.656 120.364 1.00 16.83  ? 216 LEU A CA  1 
ATOM 1450 C C   . LEU A 1 216 ? 271.022 314.824 120.756 1.00 16.83  ? 216 LEU A C   1 
ATOM 1451 O O   . LEU A 1 216 ? 270.724 314.977 121.946 1.00 16.83  ? 216 LEU A O   1 
ATOM 1452 C CB  . LEU A 1 216 ? 273.028 315.957 119.790 1.00 16.83  ? 216 LEU A CB  1 
ATOM 1453 C CG  . LEU A 1 216 ? 274.533 316.194 119.793 1.00 16.83  ? 216 LEU A CG  1 
ATOM 1454 C CD1 . LEU A 1 216 ? 274.831 317.371 118.939 1.00 16.83  ? 216 LEU A CD1 1 
ATOM 1455 C CD2 . LEU A 1 216 ? 275.014 316.442 121.171 1.00 16.83  ? 216 LEU A CD2 1 
ATOM 1456 N N   . TRP A 1 217 ? 270.105 314.777 119.779 1.00 28.56  ? 217 TRP A N   1 
ATOM 1457 C CA  . TRP A 1 217 ? 268.681 314.854 120.079 1.00 28.56  ? 217 TRP A CA  1 
ATOM 1458 C C   . TRP A 1 217 ? 268.251 313.707 120.972 1.00 28.56  ? 217 TRP A C   1 
ATOM 1459 O O   . TRP A 1 217 ? 267.563 313.927 121.973 1.00 28.56  ? 217 TRP A O   1 
ATOM 1460 C CB  . TRP A 1 217 ? 267.852 314.864 118.794 1.00 28.56  ? 217 TRP A CB  1 
ATOM 1461 C CG  . TRP A 1 217 ? 266.390 314.936 119.081 1.00 28.56  ? 217 TRP A CG  1 
ATOM 1462 C CD1 . TRP A 1 217 ? 265.660 316.055 119.250 1.00 28.56  ? 217 TRP A CD1 1 
ATOM 1463 C CD2 . TRP A 1 217 ? 265.483 313.836 119.270 1.00 28.56  ? 217 TRP A CD2 1 
ATOM 1464 N NE1 . TRP A 1 217 ? 264.358 315.736 119.534 1.00 28.56  ? 217 TRP A NE1 1 
ATOM 1465 C CE2 . TRP A 1 217 ? 264.230 314.377 119.553 1.00 28.56  ? 217 TRP A CE2 1 
ATOM 1466 C CE3 . TRP A 1 217 ? 265.620 312.449 119.235 1.00 28.56  ? 217 TRP A CE3 1 
ATOM 1467 C CZ2 . TRP A 1 217 ? 263.127 313.587 119.800 1.00 28.56  ? 217 TRP A CZ2 1 
ATOM 1468 C CZ3 . TRP A 1 217 ? 264.526 311.672 119.485 1.00 28.56  ? 217 TRP A CZ3 1 
ATOM 1469 C CH2 . TRP A 1 217 ? 263.299 312.236 119.762 1.00 28.56  ? 217 TRP A CH2 1 
ATOM 1470 N N   . PHE A 1 218 ? 268.670 312.480 120.640 1.00 28.56  ? 218 PHE A N   1 
ATOM 1471 C CA  . PHE A 1 218 ? 268.242 311.308 121.393 1.00 28.56  ? 218 PHE A CA  1 
ATOM 1472 C C   . PHE A 1 218 ? 268.732 311.352 122.826 1.00 28.56  ? 218 PHE A C   1 
ATOM 1473 O O   . PHE A 1 218 ? 267.971 311.075 123.757 1.00 28.56  ? 218 PHE A O   1 
ATOM 1474 C CB  . PHE A 1 218 ? 268.720 310.039 120.699 1.00 28.56  ? 218 PHE A CB  1 
ATOM 1475 C CG  . PHE A 1 218 ? 268.257 308.780 121.363 1.00 28.56  ? 218 PHE A CG  1 
ATOM 1476 C CD1 . PHE A 1 218 ? 266.921 308.463 121.405 1.00 28.56  ? 218 PHE A CD1 1 
ATOM 1477 C CD2 . PHE A 1 218 ? 269.157 307.910 121.940 1.00 28.56  ? 218 PHE A CD2 1 
ATOM 1478 C CE1 . PHE A 1 218 ? 266.496 307.316 122.009 1.00 28.56  ? 218 PHE A CE1 1 
ATOM 1479 C CE2 . PHE A 1 218 ? 268.732 306.764 122.547 1.00 28.56  ? 218 PHE A CE2 1 
ATOM 1480 C CZ  . PHE A 1 218 ? 267.404 306.469 122.581 1.00 28.56  ? 218 PHE A CZ  1 
ATOM 1481 N N   . HIS A 1 219 ? 269.963 311.797 123.037 1.00 28.56  ? 219 HIS A N   1 
ATOM 1482 C CA  . HIS A 1 219 ? 270.488 311.733 124.392 1.00 28.56  ? 219 HIS A CA  1 
ATOM 1483 C C   . HIS A 1 219 ? 270.072 312.913 125.251 1.00 28.56  ? 219 HIS A C   1 
ATOM 1484 O O   . HIS A 1 219 ? 269.791 312.730 126.441 1.00 28.56  ? 219 HIS A O   1 
ATOM 1485 C CB  . HIS A 1 219 ? 271.998 311.597 124.337 1.00 28.56  ? 219 HIS A CB  1 
ATOM 1486 C CG  . HIS A 1 219 ? 272.438 310.251 123.878 1.00 28.56  ? 219 HIS A CG  1 
ATOM 1487 N ND1 . HIS A 1 219 ? 272.006 309.093 124.482 1.00 28.56  ? 219 HIS A ND1 1 
ATOM 1488 C CD2 . HIS A 1 219 ? 273.235 309.872 122.856 1.00 28.56  ? 219 HIS A CD2 1 
ATOM 1489 C CE1 . HIS A 1 219 ? 272.536 308.059 123.862 1.00 28.56  ? 219 HIS A CE1 1 
ATOM 1490 N NE2 . HIS A 1 219 ? 273.288 308.504 122.875 1.00 28.56  ? 219 HIS A NE2 1 
ATOM 1491 N N   . ILE A 1 220 ? 269.985 314.110 124.669 1.00 15.45  ? 220 ILE A N   1 
ATOM 1492 C CA  . ILE A 1 220 ? 269.463 315.260 125.397 1.00 15.45  ? 220 ILE A CA  1 
ATOM 1493 C C   . ILE A 1 220 ? 268.003 315.042 125.769 1.00 15.45  ? 220 ILE A C   1 
ATOM 1494 O O   . ILE A 1 220 ? 267.599 315.282 126.911 1.00 15.45  ? 220 ILE A O   1 
ATOM 1495 C CB  . ILE A 1 220 ? 269.659 316.529 124.554 1.00 15.45  ? 220 ILE A CB  1 
ATOM 1496 C CG1 . ILE A 1 220 ? 271.105 316.960 124.605 1.00 15.45  ? 220 ILE A CG1 1 
ATOM 1497 C CG2 . ILE A 1 220 ? 268.821 317.657 125.045 1.00 15.45  ? 220 ILE A CG2 1 
ATOM 1498 C CD1 . ILE A 1 220 ? 271.485 317.783 123.460 1.00 15.45  ? 220 ILE A CD1 1 
ATOM 1499 N N   . SER A 1 221 ? 267.207 314.513 124.837 1.00 12.57  ? 221 SER A N   1 
ATOM 1500 C CA  . SER A 1 221 ? 265.803 314.268 125.104 1.00 12.57  ? 221 SER A CA  1 
ATOM 1501 C C   . SER A 1 221 ? 265.592 313.110 126.059 1.00 12.57  ? 221 SER A C   1 
ATOM 1502 O O   . SER A 1 221 ? 264.613 313.110 126.802 1.00 12.57  ? 221 SER A O   1 
ATOM 1503 C CB  . SER A 1 221 ? 265.093 314.015 123.794 1.00 12.57  ? 221 SER A CB  1 
ATOM 1504 O OG  . SER A 1 221 ? 265.287 315.119 122.943 1.00 12.57  ? 221 SER A OG  1 
ATOM 1505 N N   . CYS A 1 222 ? 266.480 312.121 126.072 1.00 15.13  ? 222 CYS A N   1 
ATOM 1506 C CA  . CYS A 1 222 ? 266.333 311.062 127.058 1.00 15.13  ? 222 CYS A CA  1 
ATOM 1507 C C   . CYS A 1 222 ? 266.758 311.507 128.445 1.00 15.13  ? 222 CYS A C   1 
ATOM 1508 O O   . CYS A 1 222 ? 266.255 310.980 129.438 1.00 15.13  ? 222 CYS A O   1 
ATOM 1509 C CB  . CYS A 1 222 ? 267.137 309.840 126.643 1.00 15.13  ? 222 CYS A CB  1 
ATOM 1510 S SG  . CYS A 1 222 ? 266.248 308.656 125.644 1.00 15.13  ? 222 CYS A SG  1 
ATOM 1511 N N   . LEU A 1 223 ? 267.683 312.458 128.537 1.00 13.48  ? 223 LEU A N   1 
ATOM 1512 C CA  . LEU A 1 223 ? 268.037 313.007 129.840 1.00 13.48  ? 223 LEU A CA  1 
ATOM 1513 C C   . LEU A 1 223 ? 266.981 313.964 130.357 1.00 13.48  ? 223 LEU A C   1 
ATOM 1514 O O   . LEU A 1 223 ? 266.756 314.039 131.565 1.00 13.48  ? 223 LEU A O   1 
ATOM 1515 C CB  . LEU A 1 223 ? 269.372 313.734 129.760 1.00 13.48  ? 223 LEU A CB  1 
ATOM 1516 C CG  . LEU A 1 223 ? 270.623 312.882 129.722 1.00 13.48  ? 223 LEU A CG  1 
ATOM 1517 C CD1 . LEU A 1 223 ? 271.781 313.702 129.248 1.00 13.48  ? 223 LEU A CD1 1 
ATOM 1518 C CD2 . LEU A 1 223 ? 270.877 312.360 131.091 1.00 13.48  ? 223 LEU A CD2 1 
ATOM 1519 N N   . THR A 1 224 ? 266.330 314.699 129.465 1.00 28.56  ? 224 THR A N   1 
ATOM 1520 C CA  . THR A 1 224 ? 265.348 315.680 129.892 1.00 28.56  ? 224 THR A CA  1 
ATOM 1521 C C   . THR A 1 224 ? 264.022 315.033 130.250 1.00 28.56  ? 224 THR A C   1 
ATOM 1522 O O   . THR A 1 224 ? 263.486 315.266 131.336 1.00 28.56  ? 224 THR A O   1 
ATOM 1523 C CB  . THR A 1 224 ? 265.134 316.711 128.799 1.00 28.56  ? 224 THR A CB  1 
ATOM 1524 O OG1 . THR A 1 224 ? 266.390 317.231 128.370 1.00 28.56  ? 224 THR A OG1 1 
ATOM 1525 C CG2 . THR A 1 224 ? 264.335 317.810 129.334 1.00 28.56  ? 224 THR A CG2 1 
ATOM 1526 N N   . PHE A 1 225 ? 263.476 314.219 129.356 1.00 16.89  ? 225 PHE A N   1 
ATOM 1527 C CA  . PHE A 1 225 ? 262.107 313.754 129.484 1.00 16.89  ? 225 PHE A CA  1 
ATOM 1528 C C   . PHE A 1 225 ? 261.990 312.322 129.952 1.00 16.89  ? 225 PHE A C   1 
ATOM 1529 O O   . PHE A 1 225 ? 260.874 311.845 130.132 1.00 16.89  ? 225 PHE A O   1 
ATOM 1530 C CB  . PHE A 1 225 ? 261.388 313.917 128.156 1.00 16.89  ? 225 PHE A CB  1 
ATOM 1531 C CG  . PHE A 1 225 ? 261.427 315.302 127.641 1.00 16.89  ? 225 PHE A CG  1 
ATOM 1532 C CD1 . PHE A 1 225 ? 260.649 316.270 128.205 1.00 16.89  ? 225 PHE A CD1 1 
ATOM 1533 C CD2 . PHE A 1 225 ? 262.268 315.647 126.616 1.00 16.89  ? 225 PHE A CD2 1 
ATOM 1534 C CE1 . PHE A 1 225 ? 260.701 317.551 127.753 1.00 16.89  ? 225 PHE A CE1 1 
ATOM 1535 C CE2 . PHE A 1 225 ? 262.312 316.926 126.159 1.00 16.89  ? 225 PHE A CE2 1 
ATOM 1536 C CZ  . PHE A 1 225 ? 261.524 317.871 126.732 1.00 16.89  ? 225 PHE A CZ  1 
ATOM 1537 N N   . GLY A 1 226 ? 263.092 311.638 130.190 1.00 13.53  ? 226 GLY A N   1 
ATOM 1538 C CA  . GLY A 1 226 ? 263.054 310.220 130.467 1.00 13.53  ? 226 GLY A CA  1 
ATOM 1539 C C   . GLY A 1 226 ? 263.214 309.407 129.199 1.00 13.53  ? 226 GLY A C   1 
ATOM 1540 O O   . GLY A 1 226 ? 263.051 309.897 128.092 1.00 13.53  ? 226 GLY A O   1 
ATOM 1541 N N   . ARG A 1 227 ? 263.553 308.136 129.370 1.00 17.10  ? 227 ARG A N   1 
ATOM 1542 C CA  . ARG A 1 227 ? 263.852 307.301 128.214 1.00 17.10  ? 227 ARG A CA  1 
ATOM 1543 C C   . ARG A 1 227 ? 262.595 306.720 127.580 1.00 17.10  ? 227 ARG A C   1 
ATOM 1544 O O   . ARG A 1 227 ? 262.443 306.741 126.350 1.00 17.10  ? 227 ARG A O   1 
ATOM 1545 C CB  . ARG A 1 227 ? 264.794 306.182 128.626 1.00 17.10  ? 227 ARG A CB  1 
ATOM 1546 C CG  . ARG A 1 227 ? 265.326 305.381 127.486 1.00 17.10  ? 227 ARG A CG  1 
ATOM 1547 C CD  . ARG A 1 227 ? 266.170 304.252 128.018 1.00 17.10  ? 227 ARG A CD  1 
ATOM 1548 N NE  . ARG A 1 227 ? 265.555 303.640 129.187 1.00 17.10  ? 227 ARG A NE  1 
ATOM 1549 C CZ  . ARG A 1 227 ? 264.661 302.661 129.134 1.00 17.10  ? 227 ARG A CZ  1 
ATOM 1550 N NH1 . ARG A 1 227 ? 264.154 302.171 130.255 1.00 17.10  ? 227 ARG A NH1 1 
ATOM 1551 N NH2 . ARG A 1 227 ? 264.273 302.176 127.962 1.00 17.10  ? 227 ARG A NH2 1 
ATOM 1552 N N   . GLU A 1 228 ? 261.691 306.203 128.413 1.00 17.76  ? 228 GLU A N   1 
ATOM 1553 C CA  . GLU A 1 228 ? 260.437 305.655 127.922 1.00 17.76  ? 228 GLU A CA  1 
ATOM 1554 C C   . GLU A 1 228 ? 259.584 306.708 127.243 1.00 17.76  ? 228 GLU A C   1 
ATOM 1555 O O   . GLU A 1 228 ? 258.877 306.399 126.285 1.00 17.76  ? 228 GLU A O   1 
ATOM 1556 C CB  . GLU A 1 228 ? 259.664 305.031 129.070 1.00 17.76  ? 228 GLU A CB  1 
ATOM 1557 C CG  . GLU A 1 228 ? 260.281 303.775 129.592 1.00 17.76  ? 228 GLU A CG  1 
ATOM 1558 C CD  . GLU A 1 228 ? 261.144 304.031 130.792 1.00 17.76  ? 228 GLU A CD  1 
ATOM 1559 O OE1 . GLU A 1 228 ? 261.238 305.204 131.205 1.00 17.76  ? 228 GLU A OE1 1 
ATOM 1560 O OE2 . GLU A 1 228 ? 261.730 303.062 131.321 1.00 17.76  ? 228 GLU A OE2 1 
ATOM 1561 N N   . THR A 1 229 ? 259.650 307.953 127.706 1.00 13.53  ? 229 THR A N   1 
ATOM 1562 C CA  . THR A 1 229 ? 258.942 309.031 127.035 1.00 13.53  ? 229 THR A CA  1 
ATOM 1563 C C   . THR A 1 229 ? 259.506 309.300 125.650 1.00 13.53  ? 229 THR A C   1 
ATOM 1564 O O   . THR A 1 229 ? 258.751 309.631 124.736 1.00 13.53  ? 229 THR A O   1 
ATOM 1565 C CB  . THR A 1 229 ? 259.002 310.286 127.887 1.00 13.53  ? 229 THR A CB  1 
ATOM 1566 O OG1 . THR A 1 229 ? 258.791 309.921 129.252 1.00 13.53  ? 229 THR A OG1 1 
ATOM 1567 C CG2 . THR A 1 229 ? 257.954 311.273 127.472 1.00 13.53  ? 229 THR A CG2 1 
ATOM 1568 N N   . VAL A 1 230 ? 260.807 309.109 125.452 1.00 12.51  ? 230 VAL A N   1 
ATOM 1569 C CA  . VAL A 1 230 ? 261.346 309.332 124.119 1.00 12.51  ? 230 VAL A CA  1 
ATOM 1570 C C   . VAL A 1 230 ? 260.981 308.185 123.203 1.00 12.51  ? 230 VAL A C   1 
ATOM 1571 O O   . VAL A 1 230 ? 260.709 308.399 122.017 1.00 12.51  ? 230 VAL A O   1 
ATOM 1572 C CB  . VAL A 1 230 ? 262.858 309.575 124.191 1.00 12.51  ? 230 VAL A CB  1 
ATOM 1573 C CG1 . VAL A 1 230 ? 263.442 309.838 122.827 1.00 12.51  ? 230 VAL A CG1 1 
ATOM 1574 C CG2 . VAL A 1 230 ? 263.089 310.773 125.004 1.00 12.51  ? 230 VAL A CG2 1 
ATOM 1575 N N   . LEU A 1 231 ? 260.887 306.966 123.735 1.00 11.01  ? 231 LEU A N   1 
ATOM 1576 C CA  . LEU A 1 231 ? 260.465 305.847 122.893 1.00 11.01  ? 231 LEU A CA  1 
ATOM 1577 C C   . LEU A 1 231 ? 258.996 305.958 122.486 1.00 11.01  ? 231 LEU A C   1 
ATOM 1578 O O   . LEU A 1 231 ? 258.660 305.779 121.304 1.00 11.01  ? 231 LEU A O   1 
ATOM 1579 C CB  . LEU A 1 231 ? 260.748 304.537 123.607 1.00 11.01  ? 231 LEU A CB  1 
ATOM 1580 C CG  . LEU A 1 231 ? 262.230 304.475 123.975 1.00 11.01  ? 231 LEU A CG  1 
ATOM 1581 C CD1 . LEU A 1 231 ? 262.531 303.296 124.857 1.00 11.01  ? 231 LEU A CD1 1 
ATOM 1582 C CD2 . LEU A 1 231 ? 263.097 304.460 122.743 1.00 11.01  ? 231 LEU A CD2 1 
ATOM 1583 N N   . GLU A 1 232 ? 258.114 306.298 123.437 1.00 15.20  ? 232 GLU A N   1 
ATOM 1584 C CA  . GLU A 1 232 ? 256.719 306.567 123.095 1.00 15.20  ? 232 GLU A CA  1 
ATOM 1585 C C   . GLU A 1 232 ? 256.571 307.780 122.193 1.00 15.20  ? 232 GLU A C   1 
ATOM 1586 O O   . GLU A 1 232 ? 255.657 307.818 121.367 1.00 15.20  ? 232 GLU A O   1 
ATOM 1587 C CB  . GLU A 1 232 ? 255.880 306.753 124.350 1.00 15.20  ? 232 GLU A CB  1 
ATOM 1588 C CG  . GLU A 1 232 ? 255.945 305.599 125.316 1.00 15.20  ? 232 GLU A CG  1 
ATOM 1589 C CD  . GLU A 1 232 ? 255.061 305.796 126.538 1.00 15.20  ? 232 GLU A CD  1 
ATOM 1590 O OE1 . GLU A 1 232 ? 255.346 306.708 127.346 1.00 15.20  ? 232 GLU A OE1 1 
ATOM 1591 O OE2 . GLU A 1 232 ? 254.097 305.023 126.711 1.00 15.20  ? 232 GLU A OE2 1 
ATOM 1592 N N   . TYR A 1 233 ? 257.465 308.761 122.302 1.00 11.66  ? 233 TYR A N   1 
ATOM 1593 C CA  . TYR A 1 233 ? 257.406 309.893 121.391 1.00 11.66  ? 233 TYR A CA  1 
ATOM 1594 C C   . TYR A 1 233 ? 257.787 309.486 119.981 1.00 11.66  ? 233 TYR A C   1 
ATOM 1595 O O   . TYR A 1 233 ? 257.216 309.993 119.016 1.00 11.66  ? 233 TYR A O   1 
ATOM 1596 C CB  . TYR A 1 233 ? 258.310 311.015 121.876 1.00 11.66  ? 233 TYR A CB  1 
ATOM 1597 C CG  . TYR A 1 233 ? 258.392 312.148 120.902 1.00 11.66  ? 233 TYR A CG  1 
ATOM 1598 C CD1 . TYR A 1 233 ? 257.327 312.992 120.717 1.00 11.66  ? 233 TYR A CD1 1 
ATOM 1599 C CD2 . TYR A 1 233 ? 259.527 312.361 120.157 1.00 11.66  ? 233 TYR A CD2 1 
ATOM 1600 C CE1 . TYR A 1 233 ? 257.396 314.007 119.828 1.00 11.66  ? 233 TYR A CE1 1 
ATOM 1601 C CE2 . TYR A 1 233 ? 259.594 313.370 119.261 1.00 11.66  ? 233 TYR A CE2 1 
ATOM 1602 C CZ  . TYR A 1 233 ? 258.530 314.186 119.107 1.00 11.66  ? 233 TYR A CZ  1 
ATOM 1603 O OH  . TYR A 1 233 ? 258.591 315.208 118.216 1.00 11.66  ? 233 TYR A OH  1 
ATOM 1604 N N   . LEU A 1 234 ? 258.754 308.582 119.840 1.00 10.28  ? 234 LEU A N   1 
ATOM 1605 C CA  . LEU A 1 234 ? 259.131 308.106 118.512 1.00 10.28  ? 234 LEU A CA  1 
ATOM 1606 C C   . LEU A 1 234 ? 258.001 307.325 117.869 1.00 10.28  ? 234 LEU A C   1 
ATOM 1607 O O   . LEU A 1 234 ? 257.730 307.484 116.674 1.00 10.28  ? 234 LEU A O   1 
ATOM 1608 C CB  . LEU A 1 234 ? 260.374 307.234 118.603 1.00 10.28  ? 234 LEU A CB  1 
ATOM 1609 C CG  . LEU A 1 234 ? 261.710 307.884 118.890 1.00 10.28  ? 234 LEU A CG  1 
ATOM 1610 C CD1 . LEU A 1 234 ? 262.557 306.912 119.642 1.00 10.28  ? 234 LEU A CD1 1 
ATOM 1611 C CD2 . LEU A 1 234 ? 262.335 308.221 117.602 1.00 10.28  ? 234 LEU A CD2 1 
ATOM 1612 N N   . VAL A 1 235 ? 257.315 306.505 118.667 1.00 9.65   ? 235 VAL A N   1 
ATOM 1613 C CA  . VAL A 1 235 ? 256.161 305.747 118.183 1.00 9.65   ? 235 VAL A CA  1 
ATOM 1614 C C   . VAL A 1 235 ? 255.032 306.683 117.743 1.00 9.65   ? 235 VAL A C   1 
ATOM 1615 O O   . VAL A 1 235 ? 254.490 306.552 116.637 1.00 9.65   ? 235 VAL A O   1 
ATOM 1616 C CB  . VAL A 1 235 ? 255.701 304.766 119.270 1.00 9.65   ? 235 VAL A CB  1 
ATOM 1617 C CG1 . VAL A 1 235 ? 254.345 304.290 118.990 1.00 9.65   ? 235 VAL A CG1 1 
ATOM 1618 C CG2 . VAL A 1 235 ? 256.643 303.605 119.339 1.00 9.65   ? 235 VAL A CG2 1 
ATOM 1619 N N   . SER A 1 236 ? 254.685 307.662 118.585 1.00 14.91  ? 236 SER A N   1 
ATOM 1620 C CA  . SER A 1 236 ? 253.601 308.582 118.260 1.00 14.91  ? 236 SER A CA  1 
ATOM 1621 C C   . SER A 1 236 ? 253.953 309.521 117.119 1.00 14.91  ? 236 SER A C   1 
ATOM 1622 O O   . SER A 1 236 ? 253.070 309.906 116.352 1.00 14.91  ? 236 SER A O   1 
ATOM 1623 C CB  . SER A 1 236 ? 253.222 309.376 119.491 1.00 14.91  ? 236 SER A CB  1 
ATOM 1624 O OG  . SER A 1 236 ? 253.100 308.518 120.603 1.00 14.91  ? 236 SER A OG  1 
ATOM 1625 N N   . PHE A 1 237 ? 255.223 309.885 116.959 1.00 28.56  ? 237 PHE A N   1 
ATOM 1626 C CA  . PHE A 1 237 ? 255.600 310.644 115.776 1.00 28.56  ? 237 PHE A CA  1 
ATOM 1627 C C   . PHE A 1 237 ? 255.587 309.776 114.530 1.00 28.56  ? 237 PHE A C   1 
ATOM 1628 O O   . PHE A 1 237 ? 255.373 310.288 113.429 1.00 28.56  ? 237 PHE A O   1 
ATOM 1629 C CB  . PHE A 1 237 ? 256.967 311.282 115.956 1.00 28.56  ? 237 PHE A CB  1 
ATOM 1630 C CG  . PHE A 1 237 ? 257.199 312.453 115.059 1.00 28.56  ? 237 PHE A CG  1 
ATOM 1631 C CD1 . PHE A 1 237 ? 256.885 313.721 115.472 1.00 28.56  ? 237 PHE A CD1 1 
ATOM 1632 C CD2 . PHE A 1 237 ? 257.730 312.289 113.811 1.00 28.56  ? 237 PHE A CD2 1 
ATOM 1633 C CE1 . PHE A 1 237 ? 257.089 314.782 114.656 1.00 28.56  ? 237 PHE A CE1 1 
ATOM 1634 C CE2 . PHE A 1 237 ? 257.920 313.347 112.997 1.00 28.56  ? 237 PHE A CE2 1 
ATOM 1635 C CZ  . PHE A 1 237 ? 257.613 314.591 113.418 1.00 28.56  ? 237 PHE A CZ  1 
ATOM 1636 N N   . GLY A 1 238 ? 255.790 308.468 114.673 1.00 11.96  ? 238 GLY A N   1 
ATOM 1637 C CA  . GLY A 1 238 ? 255.599 307.592 113.532 1.00 11.96  ? 238 GLY A CA  1 
ATOM 1638 C C   . GLY A 1 238 ? 254.150 307.526 113.102 1.00 11.96  ? 238 GLY A C   1 
ATOM 1639 O O   . GLY A 1 238 ? 253.848 307.530 111.906 1.00 11.96  ? 238 GLY A O   1 
ATOM 1640 N N   . VAL A 1 239 ? 253.238 307.496 114.076 1.00 11.05  ? 239 VAL A N   1 
ATOM 1641 C CA  . VAL A 1 239 ? 251.803 307.542 113.792 1.00 11.05  ? 239 VAL A CA  1 
ATOM 1642 C C   . VAL A 1 239 ? 251.421 308.871 113.161 1.00 11.05  ? 239 VAL A C   1 
ATOM 1643 O O   . VAL A 1 239 ? 250.579 308.927 112.263 1.00 11.05  ? 239 VAL A O   1 
ATOM 1644 C CB  . VAL A 1 239 ? 251.009 307.275 115.079 1.00 11.05  ? 239 VAL A CB  1 
ATOM 1645 C CG1 . VAL A 1 239 ? 249.547 307.308 114.833 1.00 11.05  ? 239 VAL A CG1 1 
ATOM 1646 C CG2 . VAL A 1 239 ? 251.369 305.952 115.602 1.00 11.05  ? 239 VAL A CG2 1 
ATOM 1647 N N   . TRP A 1 240 ? 252.057 309.956 113.593 1.00 12.86  ? 240 TRP A N   1 
ATOM 1648 C CA  . TRP A 1 240 ? 251.724 311.261 113.039 1.00 12.86  ? 240 TRP A CA  1 
ATOM 1649 C C   . TRP A 1 240 ? 252.210 311.405 111.603 1.00 12.86  ? 240 TRP A C   1 
ATOM 1650 O O   . TRP A 1 240 ? 251.461 311.853 110.733 1.00 12.86  ? 240 TRP A O   1 
ATOM 1651 C CB  . TRP A 1 240 ? 252.300 312.370 113.906 1.00 12.86  ? 240 TRP A CB  1 
ATOM 1652 C CG  . TRP A 1 240 ? 251.812 313.702 113.482 1.00 12.86  ? 240 TRP A CG  1 
ATOM 1653 C CD1 . TRP A 1 240 ? 250.634 314.277 113.815 1.00 12.86  ? 240 TRP A CD1 1 
ATOM 1654 C CD2 . TRP A 1 240 ? 252.483 314.626 112.628 1.00 12.86  ? 240 TRP A CD2 1 
ATOM 1655 N NE1 . TRP A 1 240 ? 250.525 315.500 113.224 1.00 12.86  ? 240 TRP A NE1 1 
ATOM 1656 C CE2 . TRP A 1 240 ? 251.651 315.736 112.486 1.00 12.86  ? 240 TRP A CE2 1 
ATOM 1657 C CE3 . TRP A 1 240 ? 253.710 314.617 111.967 1.00 12.86  ? 240 TRP A CE3 1 
ATOM 1658 C CZ2 . TRP A 1 240 ? 252.003 316.828 111.718 1.00 12.86  ? 240 TRP A CZ2 1 
ATOM 1659 C CZ3 . TRP A 1 240 ? 254.056 315.702 111.207 1.00 12.86  ? 240 TRP A CZ3 1 
ATOM 1660 C CH2 . TRP A 1 240 ? 253.210 316.791 111.087 1.00 12.86  ? 240 TRP A CH2 1 
ATOM 1661 N N   . ILE A 1 241 ? 253.460 311.036 111.327 1.00 15.33  ? 241 ILE A N   1 
ATOM 1662 C CA  . ILE A 1 241 ? 253.981 311.203 109.973 1.00 15.33  ? 241 ILE A CA  1 
ATOM 1663 C C   . ILE A 1 241 ? 253.470 310.124 109.036 1.00 15.33  ? 241 ILE A C   1 
ATOM 1664 O O   . ILE A 1 241 ? 253.553 310.276 107.813 1.00 15.33  ? 241 ILE A O   1 
ATOM 1665 C CB  . ILE A 1 241 ? 255.518 311.275 110.052 1.00 15.33  ? 241 ILE A CB  1 
ATOM 1666 C CG1 . ILE A 1 241 ? 256.109 311.969 108.830 1.00 15.33  ? 241 ILE A CG1 1 
ATOM 1667 C CG2 . ILE A 1 241 ? 256.116 309.915 110.232 1.00 15.33  ? 241 ILE A CG2 1 
ATOM 1668 C CD1 . ILE A 1 241 ? 255.787 313.416 108.742 1.00 15.33  ? 241 ILE A CD1 1 
ATOM 1669 N N   . ARG A 1 242 ? 252.895 309.057 109.580 1.00 14.00  ? 242 ARG A N   1 
ATOM 1670 C CA  . ARG A 1 242 ? 252.379 307.960 108.778 1.00 14.00  ? 242 ARG A CA  1 
ATOM 1671 C C   . ARG A 1 242 ? 251.084 308.333 108.064 1.00 14.00  ? 242 ARG A C   1 
ATOM 1672 O O   . ARG A 1 242 ? 250.908 307.997 106.888 1.00 14.00  ? 242 ARG A O   1 
ATOM 1673 C CB  . ARG A 1 242 ? 252.164 306.763 109.694 1.00 14.00  ? 242 ARG A CB  1 
ATOM 1674 C CG  . ARG A 1 242 ? 252.405 305.424 109.097 1.00 14.00  ? 242 ARG A CG  1 
ATOM 1675 C CD  . ARG A 1 242 ? 252.450 304.387 110.198 1.00 14.00  ? 242 ARG A CD  1 
ATOM 1676 N NE  . ARG A 1 242 ? 251.133 304.121 110.759 1.00 14.00  ? 242 ARG A NE  1 
ATOM 1677 C CZ  . ARG A 1 242 ? 250.935 303.706 112.004 1.00 14.00  ? 242 ARG A CZ  1 
ATOM 1678 N NH1 . ARG A 1 242 ? 251.975 303.526 112.802 1.00 14.00  ? 242 ARG A NH1 1 
ATOM 1679 N NH2 . ARG A 1 242 ? 249.708 303.484 112.458 1.00 14.00  ? 242 ARG A NH2 1 
ATOM 1680 N N   . THR A 1 243 ? 250.185 309.039 108.752 1.00 11.51  ? 243 THR A N   1 
ATOM 1681 C CA  . THR A 1 243 ? 248.840 309.302 108.259 1.00 11.51  ? 243 THR A CA  1 
ATOM 1682 C C   . THR A 1 243 ? 248.848 310.237 107.051 1.00 11.51  ? 243 THR A C   1 
ATOM 1683 O O   . THR A 1 243 ? 249.762 311.044 106.890 1.00 11.51  ? 243 THR A O   1 
ATOM 1684 C CB  . THR A 1 243 ? 247.988 309.921 109.357 1.00 11.51  ? 243 THR A CB  1 
ATOM 1685 O OG1 . THR A 1 243 ? 248.637 311.084 109.848 1.00 11.51  ? 243 THR A OG1 1 
ATOM 1686 C CG2 . THR A 1 243 ? 247.827 308.968 110.477 1.00 11.51  ? 243 THR A CG2 1 
ATOM 1687 N N   . PRO A 1 244 ? 247.849 310.128 106.178 1.00 12.52  ? 244 PRO A N   1 
ATOM 1688 C CA  . PRO A 1 244 ? 247.741 311.035 105.042 1.00 12.52  ? 244 PRO A CA  1 
ATOM 1689 C C   . PRO A 1 244 ? 247.461 312.453 105.497 1.00 12.52  ? 244 PRO A C   1 
ATOM 1690 O O   . PRO A 1 244 ? 246.947 312.657 106.605 1.00 12.52  ? 244 PRO A O   1 
ATOM 1691 C CB  . PRO A 1 244 ? 246.557 310.456 104.262 1.00 12.52  ? 244 PRO A CB  1 
ATOM 1692 C CG  . PRO A 1 244 ? 246.614 309.050 104.564 1.00 12.52  ? 244 PRO A CG  1 
ATOM 1693 C CD  . PRO A 1 244 ? 246.962 308.973 105.998 1.00 12.52  ? 244 PRO A CD  1 
ATOM 1694 N N   . PRO A 1 245 ? 247.789 313.459 104.680 1.00 12.64  ? 245 PRO A N   1 
ATOM 1695 C CA  . PRO A 1 245 ? 247.682 314.844 105.147 1.00 12.64  ? 245 PRO A CA  1 
ATOM 1696 C C   . PRO A 1 245 ? 246.266 315.332 105.346 1.00 12.64  ? 245 PRO A C   1 
ATOM 1697 O O   . PRO A 1 245 ? 246.082 316.380 105.974 1.00 12.64  ? 245 PRO A O   1 
ATOM 1698 C CB  . PRO A 1 245 ? 248.381 315.637 104.040 1.00 12.64  ? 245 PRO A CB  1 
ATOM 1699 C CG  . PRO A 1 245 ? 249.255 314.662 103.384 1.00 12.64  ? 245 PRO A CG  1 
ATOM 1700 C CD  . PRO A 1 245 ? 248.491 313.395 103.393 1.00 12.64  ? 245 PRO A CD  1 
ATOM 1701 N N   . ALA A 1 246 ? 245.263 314.621 104.834 1.00 11.34  ? 246 ALA A N   1 
ATOM 1702 C CA  . ALA A 1 246 ? 243.885 315.039 105.043 1.00 11.34  ? 246 ALA A CA  1 
ATOM 1703 C C   . ALA A 1 246 ? 243.444 314.833 106.483 1.00 11.34  ? 246 ALA A C   1 
ATOM 1704 O O   . ALA A 1 246 ? 242.617 315.596 106.987 1.00 11.34  ? 246 ALA A O   1 
ATOM 1705 C CB  . ALA A 1 246 ? 242.964 314.282 104.096 1.00 11.34  ? 246 ALA A CB  1 
ATOM 1706 N N   . TYR A 1 247 ? 243.985 313.829 107.166 1.00 15.39  ? 247 TYR A N   1 
ATOM 1707 C CA  . TYR A 1 247 ? 243.510 313.467 108.493 1.00 15.39  ? 247 TYR A CA  1 
ATOM 1708 C C   . TYR A 1 247 ? 244.579 313.583 109.563 1.00 15.39  ? 247 TYR A C   1 
ATOM 1709 O O   . TYR A 1 247 ? 244.361 313.111 110.683 1.00 15.39  ? 247 TYR A O   1 
ATOM 1710 C CB  . TYR A 1 247 ? 242.941 312.048 108.483 1.00 15.39  ? 247 TYR A CB  1 
ATOM 1711 C CG  . TYR A 1 247 ? 241.931 311.848 107.401 1.00 15.39  ? 247 TYR A CG  1 
ATOM 1712 C CD1 . TYR A 1 247 ? 240.665 312.369 107.521 1.00 15.39  ? 247 TYR A CD1 1 
ATOM 1713 C CD2 . TYR A 1 247 ? 242.249 311.161 106.251 1.00 15.39  ? 247 TYR A CD2 1 
ATOM 1714 C CE1 . TYR A 1 247 ? 239.741 312.207 106.528 1.00 15.39  ? 247 TYR A CE1 1 
ATOM 1715 C CE2 . TYR A 1 247 ? 241.332 310.995 105.255 1.00 15.39  ? 247 TYR A CE2 1 
ATOM 1716 C CZ  . TYR A 1 247 ? 240.081 311.520 105.403 1.00 15.39  ? 247 TYR A CZ  1 
ATOM 1717 O OH  . TYR A 1 247 ? 239.154 311.358 104.412 1.00 15.39  ? 247 TYR A OH  1 
ATOM 1718 N N   . ARG A 1 248 ? 245.724 314.184 109.250 1.00 14.05  ? 248 ARG A N   1 
ATOM 1719 C CA  . ARG A 1 248 ? 246.612 314.373 110.388 1.00 14.05  ? 248 ARG A CA  1 
ATOM 1720 C C   . ARG A 1 248 ? 246.320 315.706 111.060 1.00 14.05  ? 248 ARG A C   1 
ATOM 1721 O O   . ARG A 1 248 ? 246.012 316.687 110.380 1.00 14.05  ? 248 ARG A O   1 
ATOM 1722 C CB  . ARG A 1 248 ? 248.075 314.324 109.968 1.00 14.05  ? 248 ARG A CB  1 
ATOM 1723 C CG  . ARG A 1 248 ? 248.431 315.243 108.843 1.00 14.05  ? 248 ARG A CG  1 
ATOM 1724 C CD  . ARG A 1 248 ? 249.919 315.396 108.706 1.00 14.05  ? 248 ARG A CD  1 
ATOM 1725 N NE  . ARG A 1 248 ? 250.559 314.183 108.241 1.00 14.05  ? 248 ARG A NE  1 
ATOM 1726 C CZ  . ARG A 1 248 ? 251.700 314.183 107.572 1.00 14.05  ? 248 ARG A CZ  1 
ATOM 1727 N NH1 . ARG A 1 248 ? 252.284 315.332 107.291 1.00 14.05  ? 248 ARG A NH1 1 
ATOM 1728 N NH2 . ARG A 1 248 ? 252.246 313.048 107.166 1.00 14.05  ? 248 ARG A NH2 1 
ATOM 1729 N N   . PRO A 1 249 ? 246.365 315.736 112.389 1.00 10.92  ? 249 PRO A N   1 
ATOM 1730 C CA  . PRO A 1 249 ? 246.198 316.991 113.086 1.00 10.92  ? 249 PRO A CA  1 
ATOM 1731 C C   . PRO A 1 249 ? 247.362 317.919 112.799 1.00 10.92  ? 249 PRO A C   1 
ATOM 1732 O O   . PRO A 1 249 ? 248.466 317.463 112.462 1.00 10.92  ? 249 PRO A O   1 
ATOM 1733 C CB  . PRO A 1 249 ? 246.164 316.569 114.564 1.00 10.92  ? 249 PRO A CB  1 
ATOM 1734 C CG  . PRO A 1 249 ? 246.675 315.223 114.590 1.00 10.92  ? 249 PRO A CG  1 
ATOM 1735 C CD  . PRO A 1 249 ? 246.307 314.607 113.316 1.00 10.92  ? 249 PRO A CD  1 
ATOM 1736 N N   . PRO A 1 250 ? 247.158 319.226 112.885 1.00 15.92  ? 250 PRO A N   1 
ATOM 1737 C CA  . PRO A 1 250 ? 248.222 320.154 112.495 1.00 15.92  ? 250 PRO A CA  1 
ATOM 1738 C C   . PRO A 1 250 ? 249.308 320.280 113.547 1.00 15.92  ? 250 PRO A C   1 
ATOM 1739 O O   . PRO A 1 250 ? 250.464 320.564 113.223 1.00 15.92  ? 250 PRO A O   1 
ATOM 1740 C CB  . PRO A 1 250 ? 247.473 321.475 112.298 1.00 15.92  ? 250 PRO A CB  1 
ATOM 1741 C CG  . PRO A 1 250 ? 246.030 321.098 112.233 1.00 15.92  ? 250 PRO A CG  1 
ATOM 1742 C CD  . PRO A 1 250 ? 245.909 319.946 113.149 1.00 15.92  ? 250 PRO A CD  1 
ATOM 1743 N N   . ASN A 1 251 ? 248.962 320.067 114.809 1.00 28.56  ? 251 ASN A N   1 
ATOM 1744 C CA  . ASN A 1 251 ? 249.972 320.099 115.855 1.00 28.56  ? 251 ASN A CA  1 
ATOM 1745 C C   . ASN A 1 251 ? 250.718 318.775 115.860 1.00 28.56  ? 251 ASN A C   1 
ATOM 1746 O O   . ASN A 1 251 ? 250.240 317.778 116.399 1.00 28.56  ? 251 ASN A O   1 
ATOM 1747 C CB  . ASN A 1 251 ? 249.365 320.434 117.216 1.00 28.56  ? 251 ASN A CB  1 
ATOM 1748 C CG  . ASN A 1 251 ? 248.033 319.748 117.484 1.00 28.56  ? 251 ASN A CG  1 
ATOM 1749 O OD1 . ASN A 1 251 ? 247.682 318.749 116.867 1.00 28.56  ? 251 ASN A OD1 1 
ATOM 1750 N ND2 . ASN A 1 251 ? 247.292 320.288 118.446 1.00 28.56  ? 251 ASN A ND2 1 
ATOM 1751 N N   . ALA A 1 252 ? 251.896 318.774 115.232 1.00 13.50  ? 252 ALA A N   1 
ATOM 1752 C CA  . ALA A 1 252 ? 252.828 317.661 115.305 1.00 13.50  ? 252 ALA A CA  1 
ATOM 1753 C C   . ALA A 1 252 ? 253.184 317.384 116.761 1.00 13.50  ? 252 ALA A C   1 
ATOM 1754 O O   . ALA A 1 252 ? 253.232 318.311 117.566 1.00 13.50  ? 252 ALA A O   1 
ATOM 1755 C CB  . ALA A 1 252 ? 254.084 317.995 114.515 1.00 13.50  ? 252 ALA A CB  1 
ATOM 1756 N N   . PRO A 1 253 ? 253.385 316.125 117.143 1.00 10.80  ? 253 PRO A N   1 
ATOM 1757 C CA  . PRO A 1 253 ? 253.572 315.829 118.561 1.00 10.80  ? 253 PRO A CA  1 
ATOM 1758 C C   . PRO A 1 253 ? 254.920 316.325 119.039 1.00 10.80  ? 253 PRO A C   1 
ATOM 1759 O O   . PRO A 1 253 ? 255.879 316.429 118.274 1.00 10.80  ? 253 PRO A O   1 
ATOM 1760 C CB  . PRO A 1 253 ? 253.471 314.304 118.626 1.00 10.80  ? 253 PRO A CB  1 
ATOM 1761 C CG  . PRO A 1 253 ? 253.823 313.860 117.331 1.00 10.80  ? 253 PRO A CG  1 
ATOM 1762 C CD  . PRO A 1 253 ? 253.473 314.906 116.336 1.00 10.80  ? 253 PRO A CD  1 
ATOM 1763 N N   . ILE A 1 254 ? 254.967 316.688 120.312 1.00 10.81  ? 254 ILE A N   1 
ATOM 1764 C CA  . ILE A 1 254 ? 256.119 317.370 120.862 1.00 10.81  ? 254 ILE A CA  1 
ATOM 1765 C C   . ILE A 1 254 ? 256.364 316.837 122.260 1.00 10.81  ? 254 ILE A C   1 
ATOM 1766 O O   . ILE A 1 254 ? 255.463 316.305 122.910 1.00 10.81  ? 254 ILE A O   1 
ATOM 1767 C CB  . ILE A 1 254 ? 255.905 318.899 120.834 1.00 10.81  ? 254 ILE A CB  1 
ATOM 1768 C CG1 . ILE A 1 254 ? 257.228 319.651 120.891 1.00 10.81  ? 254 ILE A CG1 1 
ATOM 1769 C CG2 . ILE A 1 254 ? 254.971 319.346 121.926 1.00 10.81  ? 254 ILE A CG2 1 
ATOM 1770 C CD1 . ILE A 1 254 ? 257.103 321.069 120.487 1.00 10.81  ? 254 ILE A CD1 1 
ATOM 1771 N N   . LEU A 1 255 ? 257.611 316.916 122.687 1.00 12.82  ? 255 LEU A N   1 
ATOM 1772 C CA  . LEU A 1 255 ? 257.989 316.527 124.029 1.00 12.82  ? 255 LEU A CA  1 
ATOM 1773 C C   . LEU A 1 255 ? 257.766 317.690 124.983 1.00 12.82  ? 255 LEU A C   1 
ATOM 1774 O O   . LEU A 1 255 ? 258.095 318.837 124.676 1.00 12.82  ? 255 LEU A O   1 
ATOM 1775 C CB  . LEU A 1 255 ? 259.451 316.111 124.039 1.00 12.82  ? 255 LEU A CB  1 
ATOM 1776 C CG  . LEU A 1 255 ? 259.884 314.818 123.381 1.00 12.82  ? 255 LEU A CG  1 
ATOM 1777 C CD1 . LEU A 1 255 ? 261.321 314.951 123.079 1.00 12.82  ? 255 LEU A CD1 1 
ATOM 1778 C CD2 . LEU A 1 255 ? 259.698 313.675 124.335 1.00 12.82  ? 255 LEU A CD2 1 
ATOM 1779 N N   . SER A 1 256 ? 257.187 317.393 126.137 1.00 17.21  ? 256 SER A N   1 
ATOM 1780 C CA  . SER A 1 256 ? 256.932 318.403 127.149 1.00 17.21  ? 256 SER A CA  1 
ATOM 1781 C C   . SER A 1 256 ? 256.800 317.693 128.480 1.00 17.21  ? 256 SER A C   1 
ATOM 1782 O O   . SER A 1 256 ? 256.661 316.471 128.533 1.00 17.21  ? 256 SER A O   1 
ATOM 1783 C CB  . SER A 1 256 ? 255.679 319.219 126.837 1.00 17.21  ? 256 SER A CB  1 
ATOM 1784 O OG  . SER A 1 256 ? 255.872 320.032 125.693 1.00 17.21  ? 256 SER A OG  1 
ATOM 1785 N N   . THR A 1 257 ? 256.868 318.467 129.558 1.00 27.92  ? 257 THR A N   1 
ATOM 1786 C CA  . THR A 1 257 ? 256.798 317.862 130.881 1.00 27.92  ? 257 THR A CA  1 
ATOM 1787 C C   . THR A 1 257 ? 255.715 318.530 131.715 1.00 27.92  ? 257 THR A C   1 
ATOM 1788 O O   . THR A 1 257 ? 255.050 317.871 132.519 1.00 27.92  ? 257 THR A O   1 
ATOM 1789 C CB  . THR A 1 257 ? 258.145 317.954 131.600 1.00 27.92  ? 257 THR A CB  1 
ATOM 1790 O OG1 . THR A 1 257 ? 259.202 317.646 130.689 1.00 27.92  ? 257 THR A OG1 1 
ATOM 1791 C CG2 . THR A 1 257 ? 258.197 316.925 132.712 1.00 27.92  ? 257 THR A CG2 1 
ATOM 1792 N N   . LEU A 1 258 ? 255.522 319.831 131.525 1.00 31.39  ? 258 LEU A N   1 
ATOM 1793 C CA  . LEU A 1 258 ? 254.526 320.576 132.288 1.00 31.39  ? 258 LEU A CA  1 
ATOM 1794 C C   . LEU A 1 258 ? 253.120 320.240 131.806 1.00 31.39  ? 258 LEU A C   1 
ATOM 1795 O O   . LEU A 1 258 ? 252.932 319.816 130.666 1.00 31.39  ? 258 LEU A O   1 
ATOM 1796 C CB  . LEU A 1 258 ? 254.759 322.087 132.187 1.00 31.39  ? 258 LEU A CB  1 
ATOM 1797 C CG  . LEU A 1 258 ? 254.226 322.872 130.984 1.00 31.39  ? 258 LEU A CG  1 
ATOM 1798 C CD1 . LEU A 1 258 ? 254.250 324.348 131.305 1.00 31.39  ? 258 LEU A CD1 1 
ATOM 1799 C CD2 . LEU A 1 258 ? 254.984 322.606 129.707 1.00 31.39  ? 258 LEU A CD2 1 
ATOM 1800 N N   . ASN B 1 14  ? 274.611 341.448 95.603  1.00 89.98  ? 14  ASN B N   1 
ATOM 1801 C CA  . ASN B 1 14  ? 275.212 340.357 94.845  1.00 89.98  ? 14  ASN B CA  1 
ATOM 1802 C C   . ASN B 1 14  ? 276.152 339.539 95.726  1.00 89.98  ? 14  ASN B C   1 
ATOM 1803 O O   . ASN B 1 14  ? 275.910 339.378 96.922  1.00 89.98  ? 14  ASN B O   1 
ATOM 1804 C CB  . ASN B 1 14  ? 275.962 340.900 93.627  1.00 89.98  ? 14  ASN B CB  1 
ATOM 1805 C CG  . ASN B 1 14  ? 275.158 341.935 92.862  1.00 89.98  ? 14  ASN B CG  1 
ATOM 1806 O OD1 . ASN B 1 14  ? 274.893 343.027 93.365  1.00 89.98  ? 14  ASN B OD1 1 
ATOM 1807 N ND2 . ASN B 1 14  ? 274.763 341.595 91.641  1.00 89.98  ? 14  ASN B ND2 1 
ATOM 1808 N N   . GLU B 1 15  ? 277.219 339.018 95.128  1.00 88.17  ? 15  GLU B N   1 
ATOM 1809 C CA  . GLU B 1 15  ? 278.213 338.223 95.840  1.00 88.17  ? 15  GLU B CA  1 
ATOM 1810 C C   . GLU B 1 15  ? 279.606 338.828 95.804  1.00 88.17  ? 15  GLU B C   1 
ATOM 1811 O O   . GLU B 1 15  ? 280.246 338.954 96.852  1.00 88.17  ? 15  GLU B O   1 
ATOM 1812 C CB  . GLU B 1 15  ? 278.262 336.801 95.258  1.00 88.17  ? 15  GLU B CB  1 
ATOM 1813 C CG  . GLU B 1 15  ? 279.293 335.888 95.908  1.00 88.17  ? 15  GLU B CG  1 
ATOM 1814 C CD  . GLU B 1 15  ? 278.938 335.525 97.335  1.00 88.17  ? 15  GLU B CD  1 
ATOM 1815 O OE1 . GLU B 1 15  ? 277.737 335.332 97.618  1.00 88.17  ? 15  GLU B OE1 1 
ATOM 1816 O OE2 . GLU B 1 15  ? 279.859 335.430 98.173  1.00 88.17  ? 15  GLU B OE2 1 
ATOM 1817 N N   . ASN B 1 16  ? 280.093 339.211 94.626  1.00 80.98  ? 16  ASN B N   1 
ATOM 1818 C CA  . ASN B 1 16  ? 281.420 339.790 94.476  1.00 80.98  ? 16  ASN B CA  1 
ATOM 1819 C C   . ASN B 1 16  ? 281.403 341.311 94.455  1.00 80.98  ? 16  ASN B C   1 
ATOM 1820 O O   . ASN B 1 16  ? 282.447 341.925 94.211  1.00 80.98  ? 16  ASN B O   1 
ATOM 1821 C CB  . ASN B 1 16  ? 282.081 339.270 93.194  1.00 80.98  ? 16  ASN B CB  1 
ATOM 1822 C CG  . ASN B 1 16  ? 282.388 337.789 93.255  1.00 80.98  ? 16  ASN B CG  1 
ATOM 1823 O OD1 . ASN B 1 16  ? 281.564 336.956 92.876  1.00 80.98  ? 16  ASN B OD1 1 
ATOM 1824 N ND2 . ASN B 1 16  ? 283.581 337.451 93.729  1.00 80.98  ? 16  ASN B ND2 1 
ATOM 1825 N N   . SER B 1 17  ? 280.251 341.931 94.700  1.00 74.09  ? 17  SER B N   1 
ATOM 1826 C CA  . SER B 1 17  ? 280.152 343.380 94.656  1.00 74.09  ? 17  SER B CA  1 
ATOM 1827 C C   . SER B 1 17  ? 280.802 344.006 95.887  1.00 74.09  ? 17  SER B C   1 
ATOM 1828 O O   . SER B 1 17  ? 280.983 343.367 96.927  1.00 74.09  ? 17  SER B O   1 
ATOM 1829 C CB  . SER B 1 17  ? 278.690 343.817 94.565  1.00 74.09  ? 17  SER B CB  1 
ATOM 1830 O OG  . SER B 1 17  ? 278.121 343.948 95.856  1.00 74.09  ? 17  SER B OG  1 
ATOM 1831 N N   . LEU B 1 18  ? 281.154 345.286 95.752  1.00 72.25  ? 18  LEU B N   1 
ATOM 1832 C CA  . LEU B 1 18  ? 281.743 346.028 96.859  1.00 72.25  ? 18  LEU B CA  1 
ATOM 1833 C C   . LEU B 1 18  ? 280.699 346.408 97.904  1.00 72.25  ? 18  LEU B C   1 
ATOM 1834 O O   . LEU B 1 18  ? 281.062 346.765 99.029  1.00 72.25  ? 18  LEU B O   1 
ATOM 1835 C CB  . LEU B 1 18  ? 282.457 347.273 96.313  1.00 72.25  ? 18  LEU B CB  1 
ATOM 1836 C CG  . LEU B 1 18  ? 283.332 348.176 97.193  1.00 72.25  ? 18  LEU B CG  1 
ATOM 1837 C CD1 . LEU B 1 18  ? 284.239 347.350 98.093  1.00 72.25  ? 18  LEU B CD1 1 
ATOM 1838 C CD2 . LEU B 1 18  ? 284.148 349.135 96.341  1.00 72.25  ? 18  LEU B CD2 1 
ATOM 1839 N N   . GLU B 1 19  ? 279.410 346.314 97.563  1.00 82.84  ? 19  GLU B N   1 
ATOM 1840 C CA  . GLU B 1 19  ? 278.353 346.675 98.503  1.00 82.84  ? 19  GLU B CA  1 
ATOM 1841 C C   . GLU B 1 19  ? 278.263 345.673 99.650  1.00 82.84  ? 19  GLU B C   1 
ATOM 1842 O O   . GLU B 1 19  ? 278.089 346.067 100.809 1.00 82.84  ? 19  GLU B O   1 
ATOM 1843 C CB  . GLU B 1 19  ? 277.023 346.790 97.750  1.00 82.84  ? 19  GLU B CB  1 
ATOM 1844 C CG  . GLU B 1 19  ? 275.980 347.709 98.381  1.00 82.84  ? 19  GLU B CG  1 
ATOM 1845 C CD  . GLU B 1 19  ? 275.292 347.108 99.583  1.00 82.84  ? 19  GLU B CD  1 
ATOM 1846 O OE1 . GLU B 1 19  ? 274.840 347.872 100.461 1.00 82.84  ? 19  GLU B OE1 1 
ATOM 1847 O OE2 . GLU B 1 19  ? 275.163 345.869 99.617  1.00 82.84  ? 19  GLU B OE2 1 
ATOM 1848 N N   . ILE B 1 20  ? 278.397 344.377 99.349  1.00 77.00  ? 20  ILE B N   1 
ATOM 1849 C CA  . ILE B 1 20  ? 278.385 343.352 100.391 1.00 77.00  ? 20  ILE B CA  1 
ATOM 1850 C C   . ILE B 1 20  ? 279.624 343.473 101.271 1.00 77.00  ? 20  ILE B C   1 
ATOM 1851 O O   . ILE B 1 20  ? 279.565 343.275 102.493 1.00 77.00  ? 20  ILE B O   1 
ATOM 1852 C CB  . ILE B 1 20  ? 278.280 341.952 99.757  1.00 77.00  ? 20  ILE B CB  1 
ATOM 1853 C CG1 . ILE B 1 20  ? 277.189 341.931 98.685  1.00 77.00  ? 20  ILE B CG1 1 
ATOM 1854 C CG2 . ILE B 1 20  ? 278.015 340.891 100.817 1.00 77.00  ? 20  ILE B CG2 1 
ATOM 1855 C CD1 . ILE B 1 20  ? 275.790 342.128 99.229  1.00 77.00  ? 20  ILE B CD1 1 
ATOM 1856 N N   . GLU B 1 21  ? 280.758 343.827 100.665 1.00 77.25  ? 21  GLU B N   1 
ATOM 1857 C CA  . GLU B 1 21  ? 281.990 343.995 101.421 1.00 77.25  ? 21  GLU B CA  1 
ATOM 1858 C C   . GLU B 1 21  ? 281.927 345.229 102.309 1.00 77.25  ? 21  GLU B C   1 
ATOM 1859 O O   . GLU B 1 21  ? 282.458 345.217 103.424 1.00 77.25  ? 21  GLU B O   1 
ATOM 1860 C CB  . GLU B 1 21  ? 283.171 344.076 100.451 1.00 77.25  ? 21  GLU B CB  1 
ATOM 1861 C CG  . GLU B 1 21  ? 283.326 342.867 99.501  1.00 77.25  ? 21  GLU B CG  1 
ATOM 1862 C CD  . GLU B 1 21  ? 283.152 341.498 100.153 1.00 77.25  ? 21  GLU B CD  1 
ATOM 1863 O OE1 . GLU B 1 21  ? 283.680 341.264 101.259 1.00 77.25  ? 21  GLU B OE1 1 
ATOM 1864 O OE2 . GLU B 1 21  ? 282.462 340.645 99.548  1.00 77.25  ? 21  GLU B OE2 1 
ATOM 1865 N N   . GLU B 1 22  ? 281.245 346.280 101.851 1.00 85.66  ? 22  GLU B N   1 
ATOM 1866 C CA  . GLU B 1 22  ? 281.031 347.468 102.676 1.00 85.66  ? 22  GLU B CA  1 
ATOM 1867 C C   . GLU B 1 22  ? 280.053 347.173 103.807 1.00 85.66  ? 22  GLU B C   1 
ATOM 1868 O O   . GLU B 1 22  ? 280.211 347.689 104.921 1.00 85.66  ? 22  GLU B O   1 
ATOM 1869 C CB  . GLU B 1 22  ? 280.518 348.611 101.800 1.00 85.66  ? 22  GLU B CB  1 
ATOM 1870 C CG  . GLU B 1 22  ? 280.405 349.978 102.470 1.00 85.66  ? 22  GLU B CG  1 
ATOM 1871 C CD  . GLU B 1 22  ? 281.572 350.295 103.384 1.00 85.66  ? 22  GLU B CD  1 
ATOM 1872 O OE1 . GLU B 1 22  ? 281.402 350.249 104.619 1.00 85.66  ? 22  GLU B OE1 1 
ATOM 1873 O OE2 . GLU B 1 22  ? 282.667 350.589 102.861 1.00 85.66  ? 22  GLU B OE2 1 
ATOM 1874 N N   . LEU B 1 23  ? 279.040 346.342 103.527 1.00 83.18  ? 23  LEU B N   1 
ATOM 1875 C CA  . LEU B 1 23  ? 278.118 345.866 104.556 1.00 83.18  ? 23  LEU B CA  1 
ATOM 1876 C C   . LEU B 1 23  ? 278.866 345.129 105.657 1.00 83.18  ? 23  LEU B C   1 
ATOM 1877 O O   . LEU B 1 23  ? 278.679 345.402 106.846 1.00 83.18  ? 23  LEU B O   1 
ATOM 1878 C CB  . LEU B 1 23  ? 277.079 344.934 103.934 1.00 83.18  ? 23  LEU B CB  1 
ATOM 1879 C CG  . LEU B 1 23  ? 275.821 345.441 103.239 1.00 83.18  ? 23  LEU B CG  1 
ATOM 1880 C CD1 . LEU B 1 23  ? 275.237 344.286 102.460 1.00 83.18  ? 23  LEU B CD1 1 
ATOM 1881 C CD2 . LEU B 1 23  ? 274.813 345.975 104.223 1.00 83.18  ? 23  LEU B CD2 1 
ATOM 1882 N N   . ALA B 1 24  ? 279.759 344.220 105.268 1.00 79.60  ? 24  ALA B N   1 
ATOM 1883 C CA  . ALA B 1 24  ? 280.499 343.443 106.254 1.00 79.60  ? 24  ALA B CA  1 
ATOM 1884 C C   . ALA B 1 24  ? 281.569 344.271 106.960 1.00 79.60  ? 24  ALA B C   1 
ATOM 1885 O O   . ALA B 1 24  ? 281.861 344.024 108.137 1.00 79.60  ? 24  ALA B O   1 
ATOM 1886 C CB  . ALA B 1 24  ? 281.118 342.229 105.580 1.00 79.60  ? 24  ALA B CB  1 
ATOM 1887 N N   . ARG B 1 25  ? 282.150 345.258 106.270 1.00 84.71  ? 25  ARG B N   1 
ATOM 1888 C CA  . ARG B 1 25  ? 283.110 346.159 106.901 1.00 84.71  ? 25  ARG B CA  1 
ATOM 1889 C C   . ARG B 1 25  ? 282.439 347.016 107.967 1.00 84.71  ? 25  ARG B C   1 
ATOM 1890 O O   . ARG B 1 25  ? 282.941 347.135 109.091 1.00 84.71  ? 25  ARG B O   1 
ATOM 1891 C CB  . ARG B 1 25  ? 283.769 347.044 105.844 1.00 84.71  ? 25  ARG B CB  1 
ATOM 1892 C CG  . ARG B 1 25  ? 285.031 346.471 105.232 1.00 84.71  ? 25  ARG B CG  1 
ATOM 1893 C CD  . ARG B 1 25  ? 285.702 347.501 104.339 1.00 84.71  ? 25  ARG B CD  1 
ATOM 1894 N NE  . ARG B 1 25  ? 286.912 346.982 103.710 1.00 84.71  ? 25  ARG B NE  1 
ATOM 1895 C CZ  . ARG B 1 25  ? 288.124 347.052 104.252 1.00 84.71  ? 25  ARG B CZ  1 
ATOM 1896 N NH1 . ARG B 1 25  ? 288.289 347.621 105.439 1.00 84.71  ? 25  ARG B NH1 1 
ATOM 1897 N NH2 . ARG B 1 25  ? 289.170 346.554 103.607 1.00 84.71  ? 25  ARG B NH2 1 
ATOM 1898 N N   . PHE B 1 26  ? 281.286 347.605 107.640 1.00 86.40  ? 26  PHE B N   1 
ATOM 1899 C CA  . PHE B 1 26  ? 280.559 348.356 108.652 1.00 86.40  ? 26  PHE B CA  1 
ATOM 1900 C C   . PHE B 1 26  ? 279.960 347.442 109.713 1.00 86.40  ? 26  PHE B C   1 
ATOM 1901 O O   . PHE B 1 26  ? 279.760 347.886 110.844 1.00 86.40  ? 26  PHE B O   1 
ATOM 1902 C CB  . PHE B 1 26  ? 279.473 349.212 108.004 1.00 86.40  ? 26  PHE B CB  1 
ATOM 1903 C CG  . PHE B 1 26  ? 278.917 350.269 108.915 1.00 86.40  ? 26  PHE B CG  1 
ATOM 1904 C CD1 . PHE B 1 26  ? 279.688 351.365 109.268 1.00 86.40  ? 26  PHE B CD1 1 
ATOM 1905 C CD2 . PHE B 1 26  ? 277.629 350.171 109.413 1.00 86.40  ? 26  PHE B CD2 1 
ATOM 1906 C CE1 . PHE B 1 26  ? 279.186 352.345 110.105 1.00 86.40  ? 26  PHE B CE1 1 
ATOM 1907 C CE2 . PHE B 1 26  ? 277.118 351.152 110.245 1.00 86.40  ? 26  PHE B CE2 1 
ATOM 1908 C CZ  . PHE B 1 26  ? 277.900 352.237 110.595 1.00 86.40  ? 26  PHE B CZ  1 
ATOM 1909 N N   . ALA B 1 27  ? 279.745 346.164 109.393 1.00 81.25  ? 27  ALA B N   1 
ATOM 1910 C CA  . ALA B 1 27  ? 279.302 345.193 110.386 1.00 81.25  ? 27  ALA B CA  1 
ATOM 1911 C C   . ALA B 1 27  ? 280.383 344.922 111.427 1.00 81.25  ? 27  ALA B C   1 
ATOM 1912 O O   . ALA B 1 27  ? 280.112 344.928 112.635 1.00 81.25  ? 27  ALA B O   1 
ATOM 1913 C CB  . ALA B 1 27  ? 278.894 343.898 109.685 1.00 81.25  ? 27  ALA B CB  1 
ATOM 1914 N N   . VAL B 1 28  ? 281.620 344.684 110.980 1.00 85.47  ? 28  VAL B N   1 
ATOM 1915 C CA  . VAL B 1 28  ? 282.679 344.382 111.942 1.00 85.47  ? 28  VAL B CA  1 
ATOM 1916 C C   . VAL B 1 28  ? 283.087 345.645 112.699 1.00 85.47  ? 28  VAL B C   1 
ATOM 1917 O O   . VAL B 1 28  ? 283.392 345.586 113.902 1.00 85.47  ? 28  VAL B O   1 
ATOM 1918 C CB  . VAL B 1 28  ? 283.880 343.686 111.263 1.00 85.47  ? 28  VAL B CB  1 
ATOM 1919 C CG1 . VAL B 1 28  ? 283.482 342.297 110.780 1.00 85.47  ? 28  VAL B CG1 1 
ATOM 1920 C CG2 . VAL B 1 28  ? 284.463 344.493 110.127 1.00 85.47  ? 28  VAL B CG2 1 
ATOM 1921 N N   . ASP B 1 29  ? 283.016 346.817 112.049 1.00 90.45  ? 29  ASP B N   1 
ATOM 1922 C CA  . ASP B 1 29  ? 283.258 348.060 112.779 1.00 90.45  ? 29  ASP B CA  1 
ATOM 1923 C C   . ASP B 1 29  ? 282.149 348.350 113.785 1.00 90.45  ? 29  ASP B C   1 
ATOM 1924 O O   . ASP B 1 29  ? 282.433 348.817 114.889 1.00 90.45  ? 29  ASP B O   1 
ATOM 1925 C CB  . ASP B 1 29  ? 283.440 349.231 111.815 1.00 90.45  ? 29  ASP B CB  1 
ATOM 1926 C CG  . ASP B 1 29  ? 284.598 349.025 110.857 1.00 90.45  ? 29  ASP B CG  1 
ATOM 1927 O OD1 . ASP B 1 29  ? 285.584 348.364 111.251 1.00 90.45  ? 29  ASP B OD1 1 
ATOM 1928 O OD2 . ASP B 1 29  ? 284.528 349.537 109.720 1.00 90.45  ? 29  ASP B OD2 1 
ATOM 1929 N N   . GLU B 1 30  ? 280.890 348.033 113.454 1.00 91.41  ? 30  GLU B N   1 
ATOM 1930 C CA  . GLU B 1 30  ? 279.804 348.219 114.411 1.00 91.41  ? 30  GLU B CA  1 
ATOM 1931 C C   . GLU B 1 30  ? 279.884 347.233 115.567 1.00 91.41  ? 30  GLU B C   1 
ATOM 1932 O O   . GLU B 1 30  ? 279.469 347.562 116.682 1.00 91.41  ? 30  GLU B O   1 
ATOM 1933 C CB  . GLU B 1 30  ? 278.447 348.094 113.720 1.00 91.41  ? 30  GLU B CB  1 
ATOM 1934 C CG  . GLU B 1 30  ? 277.825 349.414 113.315 1.00 91.41  ? 30  GLU B CG  1 
ATOM 1935 C CD  . GLU B 1 30  ? 276.332 349.292 113.080 1.00 91.41  ? 30  GLU B CD  1 
ATOM 1936 O OE1 . GLU B 1 30  ? 275.654 350.332 112.954 1.00 91.41  ? 30  GLU B OE1 1 
ATOM 1937 O OE2 . GLU B 1 30  ? 275.833 348.152 113.029 1.00 91.41  ? 30  GLU B OE2 1 
ATOM 1938 N N   . HIS B 1 31  ? 280.406 346.028 115.324 1.00 95.54  ? 31  HIS B N   1 
ATOM 1939 C CA  . HIS B 1 31  ? 280.697 345.123 116.433 1.00 95.54  ? 31  HIS B CA  1 
ATOM 1940 C C   . HIS B 1 31  ? 281.776 345.709 117.338 1.00 95.54  ? 31  HIS B C   1 
ATOM 1941 O O   . HIS B 1 31  ? 281.687 345.602 118.571 1.00 95.54  ? 31  HIS B O   1 
ATOM 1942 C CB  . HIS B 1 31  ? 281.120 343.753 115.903 1.00 95.54  ? 31  HIS B CB  1 
ATOM 1943 C CG  . HIS B 1 31  ? 281.329 342.725 116.973 1.00 95.54  ? 31  HIS B CG  1 
ATOM 1944 N ND1 . HIS B 1 31  ? 280.684 342.772 118.190 1.00 95.54  ? 31  HIS B ND1 1 
ATOM 1945 C CD2 . HIS B 1 31  ? 282.105 341.616 117.003 1.00 95.54  ? 31  HIS B CD2 1 
ATOM 1946 C CE1 . HIS B 1 31  ? 281.057 341.737 118.923 1.00 95.54  ? 31  HIS B CE1 1 
ATOM 1947 N NE2 . HIS B 1 31  ? 281.920 341.022 118.227 1.00 95.54  ? 31  HIS B NE2 1 
ATOM 1948 N N   . ASN B 1 32  ? 282.778 346.368 116.735 1.00 99.11  ? 32  ASN B N   1 
ATOM 1949 C CA  . ASN B 1 32  ? 283.803 347.063 117.515 1.00 99.11  ? 32  ASN B CA  1 
ATOM 1950 C C   . ASN B 1 32  ? 283.237 348.242 118.308 1.00 99.11  ? 32  ASN B C   1 
ATOM 1951 O O   . ASN B 1 32  ? 283.746 348.548 119.392 1.00 99.11  ? 32  ASN B O   1 
ATOM 1952 C CB  . ASN B 1 32  ? 284.936 347.536 116.601 1.00 99.11  ? 32  ASN B CB  1 
ATOM 1953 C CG  . ASN B 1 32  ? 285.878 346.413 116.209 1.00 99.11  ? 32  ASN B CG  1 
ATOM 1954 O OD1 . ASN B 1 32  ? 285.456 345.276 116.007 1.00 99.11  ? 32  ASN B OD1 1 
ATOM 1955 N ND2 . ASN B 1 32  ? 287.162 346.730 116.098 1.00 99.11  ? 32  ASN B ND2 1 
ATOM 1956 N N   . LYS B 1 33  ? 282.210 348.927 117.791 1.00 96.71  ? 33  LYS B N   1 
ATOM 1957 C CA  . LYS B 1 33  ? 281.570 349.973 118.596 1.00 96.71  ? 33  LYS B CA  1 
ATOM 1958 C C   . LYS B 1 33  ? 280.748 349.366 119.727 1.00 96.71  ? 33  LYS B C   1 
ATOM 1959 O O   . LYS B 1 33  ? 280.834 349.809 120.878 1.00 96.71  ? 33  LYS B O   1 
ATOM 1960 C CB  . LYS B 1 33  ? 280.664 350.898 117.768 1.00 96.71  ? 33  LYS B CB  1 
ATOM 1961 C CG  . LYS B 1 33  ? 281.045 351.221 116.347 1.00 96.71  ? 33  LYS B CG  1 
ATOM 1962 C CD  . LYS B 1 33  ? 282.405 351.890 116.231 1.00 96.71  ? 33  LYS B CD  1 
ATOM 1963 C CE  . LYS B 1 33  ? 282.535 352.606 114.896 1.00 96.71  ? 33  LYS B CE  1 
ATOM 1964 N NZ  . LYS B 1 33  ? 282.084 351.741 113.766 1.00 96.71  ? 33  LYS B NZ  1 
ATOM 1965 N N   . LYS B 1 34  ? 279.942 348.351 119.417 1.00 93.05  ? 34  LYS B N   1 
ATOM 1966 C CA  . LYS B 1 34  ? 278.921 347.903 120.356 1.00 93.05  ? 34  LYS B CA  1 
ATOM 1967 C C   . LYS B 1 34  ? 279.502 347.006 121.445 1.00 93.05  ? 34  LYS B C   1 
ATOM 1968 O O   . LYS B 1 34  ? 279.424 347.337 122.633 1.00 93.05  ? 34  LYS B O   1 
ATOM 1969 C CB  . LYS B 1 34  ? 277.794 347.188 119.602 1.00 93.05  ? 34  LYS B CB  1 
ATOM 1970 C CG  . LYS B 1 34  ? 276.940 348.104 118.733 1.00 93.05  ? 34  LYS B CG  1 
ATOM 1971 C CD  . LYS B 1 34  ? 275.681 347.403 118.248 1.00 93.05  ? 34  LYS B CD  1 
ATOM 1972 C CE  . LYS B 1 34  ? 276.005 346.154 117.448 1.00 93.05  ? 34  LYS B CE  1 
ATOM 1973 N NZ  . LYS B 1 34  ? 274.776 345.408 117.056 1.00 93.05  ? 34  LYS B NZ  1 
ATOM 1974 N N   . GLU B 1 35  ? 280.092 345.868 121.069 1.00 95.21  ? 35  GLU B N   1 
ATOM 1975 C CA  . GLU B 1 35  ? 280.439 344.870 122.077 1.00 95.21  ? 35  GLU B CA  1 
ATOM 1976 C C   . GLU B 1 35  ? 281.931 344.785 122.379 1.00 95.21  ? 35  GLU B C   1 
ATOM 1977 O O   . GLU B 1 35  ? 282.315 343.979 123.234 1.00 95.21  ? 35  GLU B O   1 
ATOM 1978 C CB  . GLU B 1 35  ? 279.923 343.486 121.667 1.00 95.21  ? 35  GLU B CB  1 
ATOM 1979 C CG  . GLU B 1 35  ? 278.444 343.250 121.948 1.00 95.21  ? 35  GLU B CG  1 
ATOM 1980 C CD  . GLU B 1 35  ? 277.537 343.902 120.925 1.00 95.21  ? 35  GLU B CD  1 
ATOM 1981 O OE1 . GLU B 1 35  ? 277.871 343.865 119.721 1.00 95.21  ? 35  GLU B OE1 1 
ATOM 1982 O OE2 . GLU B 1 35  ? 276.490 344.449 121.327 1.00 95.21  ? 35  GLU B OE2 1 
ATOM 1983 N N   . ASN B 1 36  ? 282.760 345.580 121.692 1.00 94.17  ? 36  ASN B N   1 
ATOM 1984 C CA  . ASN B 1 36  ? 284.161 345.845 122.046 1.00 94.17  ? 36  ASN B CA  1 
ATOM 1985 C C   . ASN B 1 36  ? 285.025 344.579 122.049 1.00 94.17  ? 36  ASN B C   1 
ATOM 1986 O O   . ASN B 1 36  ? 285.530 344.135 123.082 1.00 94.17  ? 36  ASN B O   1 
ATOM 1987 C CB  . ASN B 1 36  ? 284.249 346.579 123.390 1.00 94.17  ? 36  ASN B CB  1 
ATOM 1988 C CG  . ASN B 1 36  ? 284.098 348.076 123.240 1.00 94.17  ? 36  ASN B CG  1 
ATOM 1989 O OD1 . ASN B 1 36  ? 283.156 348.672 123.761 1.00 94.17  ? 36  ASN B OD1 1 
ATOM 1990 N ND2 . ASN B 1 36  ? 285.023 348.693 122.516 1.00 94.17  ? 36  ASN B ND2 1 
ATOM 1991 N N   . ALA B 1 37  ? 285.176 343.997 120.864 1.00 93.59  ? 37  ALA B N   1 
ATOM 1992 C CA  . ALA B 1 37  ? 286.153 342.947 120.622 1.00 93.59  ? 37  ALA B CA  1 
ATOM 1993 C C   . ALA B 1 37  ? 287.045 343.355 119.457 1.00 93.59  ? 37  ALA B C   1 
ATOM 1994 O O   . ALA B 1 37  ? 286.646 344.136 118.587 1.00 93.59  ? 37  ALA B O   1 
ATOM 1995 C CB  . ALA B 1 37  ? 285.474 341.600 120.334 1.00 93.59  ? 37  ALA B CB  1 
ATOM 1996 N N   . LEU B 1 38  ? 288.270 342.830 119.450 1.00 93.52  ? 38  LEU B N   1 
ATOM 1997 C CA  . LEU B 1 38  ? 289.195 343.102 118.357 1.00 93.52  ? 38  LEU B CA  1 
ATOM 1998 C C   . LEU B 1 38  ? 288.788 342.281 117.139 1.00 93.52  ? 38  LEU B C   1 
ATOM 1999 O O   . LEU B 1 38  ? 288.487 341.087 117.255 1.00 93.52  ? 38  LEU B O   1 
ATOM 2000 C CB  . LEU B 1 38  ? 290.642 342.812 118.776 1.00 93.52  ? 38  LEU B CB  1 
ATOM 2001 C CG  . LEU B 1 38  ? 291.315 341.430 118.797 1.00 93.52  ? 38  LEU B CG  1 
ATOM 2002 C CD1 . LEU B 1 38  ? 292.809 341.576 119.021 1.00 93.52  ? 38  LEU B CD1 1 
ATOM 2003 C CD2 . LEU B 1 38  ? 290.715 340.524 119.859 1.00 93.52  ? 38  LEU B CD2 1 
ATOM 2004 N N   . LEU B 1 39  ? 288.734 342.930 115.976 1.00 91.26  ? 39  LEU B N   1 
ATOM 2005 C CA  . LEU B 1 39  ? 288.110 342.300 114.823 1.00 91.26  ? 39  LEU B CA  1 
ATOM 2006 C C   . LEU B 1 39  ? 288.564 342.990 113.543 1.00 91.26  ? 39  LEU B C   1 
ATOM 2007 O O   . LEU B 1 39  ? 288.696 344.216 113.505 1.00 91.26  ? 39  LEU B O   1 
ATOM 2008 C CB  . LEU B 1 39  ? 286.581 342.359 114.940 1.00 91.26  ? 39  LEU B CB  1 
ATOM 2009 C CG  . LEU B 1 39  ? 285.736 341.660 113.881 1.00 91.26  ? 39  LEU B CG  1 
ATOM 2010 C CD1 . LEU B 1 39  ? 286.268 340.270 113.676 1.00 91.26  ? 39  LEU B CD1 1 
ATOM 2011 C CD2 . LEU B 1 39  ? 284.304 341.593 114.328 1.00 91.26  ? 39  LEU B CD2 1 
ATOM 2012 N N   . GLU B 1 40  ? 288.799 342.191 112.503 1.00 86.57  ? 40  GLU B N   1 
ATOM 2013 C CA  . GLU B 1 40  ? 289.075 342.687 111.164 1.00 86.57  ? 40  GLU B CA  1 
ATOM 2014 C C   . GLU B 1 40  ? 288.543 341.675 110.158 1.00 86.57  ? 40  GLU B C   1 
ATOM 2015 O O   . GLU B 1 40  ? 288.281 340.519 110.499 1.00 86.57  ? 40  GLU B O   1 
ATOM 2016 C CB  . GLU B 1 40  ? 290.575 342.974 110.928 1.00 86.57  ? 40  GLU B CB  1 
ATOM 2017 C CG  . GLU B 1 40  ? 291.547 341.801 111.086 1.00 86.57  ? 40  GLU B CG  1 
ATOM 2018 C CD  . GLU B 1 40  ? 291.807 341.404 112.533 1.00 86.57  ? 40  GLU B CD  1 
ATOM 2019 O OE1 . GLU B 1 40  ? 291.610 342.249 113.430 1.00 86.57  ? 40  GLU B OE1 1 
ATOM 2020 O OE2 . GLU B 1 40  ? 292.199 340.245 112.776 1.00 86.57  ? 40  GLU B OE2 1 
ATOM 2021 N N   . PHE B 1 41  ? 288.378 342.122 108.915 1.00 82.80  ? 41  PHE B N   1 
ATOM 2022 C CA  . PHE B 1 41  ? 287.569 341.422 107.928 1.00 82.80  ? 41  PHE B CA  1 
ATOM 2023 C C   . PHE B 1 41  ? 288.313 341.265 106.604 1.00 82.80  ? 41  PHE B C   1 
ATOM 2024 O O   . PHE B 1 41  ? 289.105 342.130 106.216 1.00 82.80  ? 41  PHE B O   1 
ATOM 2025 C CB  . PHE B 1 41  ? 286.244 342.182 107.718 1.00 82.80  ? 41  PHE B CB  1 
ATOM 2026 C CG  . PHE B 1 41  ? 285.464 341.714 106.539 1.00 82.80  ? 41  PHE B CG  1 
ATOM 2027 C CD1 . PHE B 1 41  ? 284.823 340.492 106.574 1.00 82.80  ? 41  PHE B CD1 1 
ATOM 2028 C CD2 . PHE B 1 41  ? 285.395 342.481 105.385 1.00 82.80  ? 41  PHE B CD2 1 
ATOM 2029 C CE1 . PHE B 1 41  ? 284.119 340.045 105.493 1.00 82.80  ? 41  PHE B CE1 1 
ATOM 2030 C CE2 . PHE B 1 41  ? 284.694 342.032 104.292 1.00 82.80  ? 41  PHE B CE2 1 
ATOM 2031 C CZ  . PHE B 1 41  ? 284.067 340.807 104.344 1.00 82.80  ? 41  PHE B CZ  1 
ATOM 2032 N N   . VAL B 1 42  ? 288.053 340.147 105.909 1.00 81.40  ? 42  VAL B N   1 
ATOM 2033 C CA  . VAL B 1 42  ? 288.503 339.962 104.528 1.00 81.40  ? 42  VAL B CA  1 
ATOM 2034 C C   . VAL B 1 42  ? 287.337 339.653 103.585 1.00 81.40  ? 42  VAL B C   1 
ATOM 2035 O O   . VAL B 1 42  ? 287.100 340.398 102.627 1.00 81.40  ? 42  VAL B O   1 
ATOM 2036 C CB  . VAL B 1 42  ? 289.596 338.875 104.435 1.00 81.40  ? 42  VAL B CB  1 
ATOM 2037 C CG1 . VAL B 1 42  ? 289.789 338.396 102.998 1.00 81.40  ? 42  VAL B CG1 1 
ATOM 2038 C CG2 . VAL B 1 42  ? 290.913 339.419 104.947 1.00 81.40  ? 42  VAL B CG2 1 
ATOM 2039 N N   . ARG B 1 43  ? 286.594 338.569 103.835 1.00 83.56  ? 43  ARG B N   1 
ATOM 2040 C CA  . ARG B 1 43  ? 285.769 337.986 102.780 1.00 83.56  ? 43  ARG B CA  1 
ATOM 2041 C C   . ARG B 1 43  ? 284.415 337.518 103.296 1.00 83.56  ? 43  ARG B C   1 
ATOM 2042 O O   . ARG B 1 43  ? 284.326 336.941 104.383 1.00 83.56  ? 43  ARG B O   1 
ATOM 2043 C CB  . ARG B 1 43  ? 286.501 336.808 102.121 1.00 83.56  ? 43  ARG B CB  1 
ATOM 2044 C CG  . ARG B 1 43  ? 285.825 336.249 100.880 1.00 83.56  ? 43  ARG B CG  1 
ATOM 2045 C CD  . ARG B 1 43  ? 285.973 334.744 100.803 1.00 83.56  ? 43  ARG B CD  1 
ATOM 2046 N NE  . ARG B 1 43  ? 285.153 334.175 99.740  1.00 83.56  ? 43  ARG B NE  1 
ATOM 2047 C CZ  . ARG B 1 43  ? 285.082 332.878 99.468  1.00 83.56  ? 43  ARG B CZ  1 
ATOM 2048 N NH1 . ARG B 1 43  ? 285.793 332.015 100.179 1.00 83.56  ? 43  ARG B NH1 1 
ATOM 2049 N NH2 . ARG B 1 43  ? 284.307 332.442 98.484  1.00 83.56  ? 43  ARG B NH2 1 
ATOM 2050 N N   . VAL B 1 44  ? 283.366 337.793 102.525 1.00 79.60  ? 44  VAL B N   1 
ATOM 2051 C CA  . VAL B 1 44  ? 282.074 337.133 102.689 1.00 79.60  ? 44  VAL B CA  1 
ATOM 2052 C C   . VAL B 1 44  ? 282.061 335.916 101.772 1.00 79.60  ? 44  VAL B C   1 
ATOM 2053 O O   . VAL B 1 44  ? 282.399 336.022 100.586 1.00 79.60  ? 44  VAL B O   1 
ATOM 2054 C CB  . VAL B 1 44  ? 280.914 338.086 102.350 1.00 79.60  ? 44  VAL B CB  1 
ATOM 2055 C CG1 . VAL B 1 44  ? 279.573 337.385 102.524 1.00 79.60  ? 44  VAL B CG1 1 
ATOM 2056 C CG2 . VAL B 1 44  ? 280.982 339.346 103.184 1.00 79.60  ? 44  VAL B CG2 1 
ATOM 2057 N N   . VAL B 1 45  ? 281.689 334.757 102.310 1.00 78.31  ? 45  VAL B N   1 
ATOM 2058 C CA  . VAL B 1 45  ? 281.618 333.570 101.465 1.00 78.31  ? 45  VAL B CA  1 
ATOM 2059 C C   . VAL B 1 45  ? 280.230 333.388 100.845 1.00 78.31  ? 45  VAL B C   1 
ATOM 2060 O O   . VAL B 1 45  ? 280.118 332.836 99.746  1.00 78.31  ? 45  VAL B O   1 
ATOM 2061 C CB  . VAL B 1 45  ? 282.066 332.308 102.234 1.00 78.31  ? 45  VAL B CB  1 
ATOM 2062 C CG1 . VAL B 1 45  ? 283.509 332.449 102.678 1.00 78.31  ? 45  VAL B CG1 1 
ATOM 2063 C CG2 . VAL B 1 45  ? 281.182 332.023 103.439 1.00 78.31  ? 45  VAL B CG2 1 
ATOM 2064 N N   . LYS B 1 46  ? 279.168 333.841 101.513 1.00 77.33  ? 46  LYS B N   1 
ATOM 2065 C CA  . LYS B 1 46  ? 277.821 333.720 100.974 1.00 77.33  ? 46  LYS B CA  1 
ATOM 2066 C C   . LYS B 1 46  ? 276.964 334.840 101.548 1.00 77.33  ? 46  LYS B C   1 
ATOM 2067 O O   . LYS B 1 46  ? 277.059 335.144 102.741 1.00 77.33  ? 46  LYS B O   1 
ATOM 2068 C CB  . LYS B 1 46  ? 277.211 332.348 101.306 1.00 77.33  ? 46  LYS B CB  1 
ATOM 2069 C CG  . LYS B 1 46  ? 275.829 332.097 100.718 1.00 77.33  ? 46  LYS B CG  1 
ATOM 2070 C CD  . LYS B 1 46  ? 275.786 332.442 99.235  1.00 77.33  ? 46  LYS B CD  1 
ATOM 2071 C CE  . LYS B 1 46  ? 274.425 332.972 98.828  1.00 77.33  ? 46  LYS B CE  1 
ATOM 2072 N NZ  . LYS B 1 46  ? 274.432 333.499 97.438  1.00 77.33  ? 46  LYS B NZ  1 
ATOM 2073 N N   . ALA B 1 47  ? 276.140 335.459 100.699 1.00 78.19  ? 47  ALA B N   1 
ATOM 2074 C CA  . ALA B 1 47  ? 275.216 336.516 101.109 1.00 78.19  ? 47  ALA B CA  1 
ATOM 2075 C C   . ALA B 1 47  ? 273.860 336.294 100.439 1.00 78.19  ? 47  ALA B C   1 
ATOM 2076 O O   . ALA B 1 47  ? 273.617 336.809 99.345  1.00 78.19  ? 47  ALA B O   1 
ATOM 2077 C CB  . ALA B 1 47  ? 275.786 337.891 100.776 1.00 78.19  ? 47  ALA B CB  1 
ATOM 2078 N N   . LYS B 1 48  ? 272.979 335.541 101.100 1.00 81.38  ? 48  LYS B N   1 
ATOM 2079 C CA  . LYS B 1 48  ? 271.605 335.396 100.634 1.00 81.38  ? 48  LYS B CA  1 
ATOM 2080 C C   . LYS B 1 48  ? 270.836 336.698 100.848 1.00 81.38  ? 48  LYS B C   1 
ATOM 2081 O O   . LYS B 1 48  ? 271.238 337.559 101.629 1.00 81.38  ? 48  LYS B O   1 
ATOM 2082 C CB  . LYS B 1 48  ? 270.900 334.253 101.367 1.00 81.38  ? 48  LYS B CB  1 
ATOM 2083 C CG  . LYS B 1 48  ? 271.440 332.874 101.052 1.00 81.38  ? 48  LYS B CG  1 
ATOM 2084 C CD  . LYS B 1 48  ? 270.730 332.257 99.859  1.00 81.38  ? 48  LYS B CD  1 
ATOM 2085 C CE  . LYS B 1 48  ? 269.817 331.115 100.288 1.00 81.38  ? 48  LYS B CE  1 
ATOM 2086 N NZ  . LYS B 1 48  ? 269.171 330.439 99.124  1.00 81.38  ? 48  LYS B NZ  1 
ATOM 2087 N N   . GLU B 1 49  ? 269.709 336.836 100.147 1.00 81.37  ? 49  GLU B N   1 
ATOM 2088 C CA  . GLU B 1 49  ? 268.917 338.057 100.217 1.00 81.37  ? 49  GLU B CA  1 
ATOM 2089 C C   . GLU B 1 49  ? 267.454 337.724 100.468 1.00 81.37  ? 49  GLU B C   1 
ATOM 2090 O O   . GLU B 1 49  ? 266.947 336.709 99.983  1.00 81.37  ? 49  GLU B O   1 
ATOM 2091 C CB  . GLU B 1 49  ? 269.037 338.886 98.928  1.00 81.37  ? 49  GLU B CB  1 
ATOM 2092 C CG  . GLU B 1 49  ? 268.984 338.075 97.639  1.00 81.37  ? 49  GLU B CG  1 
ATOM 2093 C CD  . GLU B 1 49  ? 270.357 337.783 97.069  1.00 81.37  ? 49  GLU B CD  1 
ATOM 2094 O OE1 . GLU B 1 49  ? 271.318 337.684 97.855  1.00 81.37  ? 49  GLU B OE1 1 
ATOM 2095 O OE2 . GLU B 1 49  ? 270.478 337.658 95.832  1.00 81.37  ? 49  GLU B OE2 1 
ATOM 2096 N N   . GLN B 1 50  ? 266.786 338.579 101.250 1.00 88.42  ? 50  GLN B N   1 
ATOM 2097 C CA  . GLN B 1 50  ? 265.345 338.492 101.501 1.00 88.42  ? 50  GLN B CA  1 
ATOM 2098 C C   . GLN B 1 50  ? 264.774 339.904 101.441 1.00 88.42  ? 50  GLN B C   1 
ATOM 2099 O O   . GLN B 1 50  ? 264.909 340.669 102.401 1.00 88.42  ? 50  GLN B O   1 
ATOM 2100 C CB  . GLN B 1 50  ? 265.030 337.851 102.859 1.00 88.42  ? 50  GLN B CB  1 
ATOM 2101 C CG  . GLN B 1 50  ? 265.695 336.509 103.158 1.00 88.42  ? 50  GLN B CG  1 
ATOM 2102 C CD  . GLN B 1 50  ? 265.906 336.284 104.642 1.00 88.42  ? 50  GLN B CD  1 
ATOM 2103 O OE1 . GLN B 1 50  ? 265.222 335.471 105.263 1.00 88.42  ? 50  GLN B OE1 1 
ATOM 2104 N NE2 . GLN B 1 50  ? 266.867 336.997 105.216 1.00 88.42  ? 50  GLN B NE2 1 
ATOM 2105 N N   . ILE B 1 51  ? 264.128 340.248 100.328 1.00 82.82  ? 51  ILE B N   1 
ATOM 2106 C CA  . ILE B 1 51  ? 263.545 341.572 100.139 1.00 82.82  ? 51  ILE B CA  1 
ATOM 2107 C C   . ILE B 1 51  ? 262.091 341.555 100.607 1.00 82.82  ? 51  ILE B C   1 
ATOM 2108 O O   . ILE B 1 51  ? 261.359 340.578 100.399 1.00 82.82  ? 51  ILE B O   1 
ATOM 2109 C CB  . ILE B 1 51  ? 263.689 342.027 98.667  1.00 82.82  ? 51  ILE B CB  1 
ATOM 2110 C CG1 . ILE B 1 51  ? 263.191 343.464 98.463  1.00 82.82  ? 51  ILE B CG1 1 
ATOM 2111 C CG2 . ILE B 1 51  ? 263.039 341.045 97.683  1.00 82.82  ? 51  ILE B CG2 1 
ATOM 2112 C CD1 . ILE B 1 51  ? 264.131 344.521 98.997  1.00 82.82  ? 51  ILE B CD1 1 
ATOM 2113 N N   . ILE B 1 52  ? 261.684 342.621 101.290 1.00 78.08  ? 52  ILE B N   1 
ATOM 2114 C CA  . ILE B 1 52  ? 260.320 342.739 101.792 1.00 78.08  ? 52  ILE B CA  1 
ATOM 2115 C C   . ILE B 1 52  ? 259.783 344.142 101.528 1.00 78.08  ? 52  ILE B C   1 
ATOM 2116 O O   . ILE B 1 52  ? 260.514 345.024 101.077 1.00 78.08  ? 52  ILE B O   1 
ATOM 2117 C CB  . ILE B 1 52  ? 260.246 342.397 103.292 1.00 78.08  ? 52  ILE B CB  1 
ATOM 2118 C CG1 . ILE B 1 52  ? 258.815 342.548 103.809 1.00 78.08  ? 52  ILE B CG1 1 
ATOM 2119 C CG2 . ILE B 1 52  ? 261.185 343.283 104.089 1.00 78.08  ? 52  ILE B CG2 1 
ATOM 2120 C CD1 . ILE B 1 52  ? 258.512 341.689 105.017 1.00 78.08  ? 52  ILE B CD1 1 
ATOM 2121 N N   . ASP B 1 59  ? 264.943 347.264 101.840 1.00 89.89  ? 59  ASP B N   1 
ATOM 2122 C CA  . ASP B 1 59  ? 264.479 346.384 102.906 1.00 89.89  ? 59  ASP B CA  1 
ATOM 2123 C C   . ASP B 1 59  ? 264.949 344.951 102.680 1.00 89.89  ? 59  ASP B C   1 
ATOM 2124 O O   . ASP B 1 59  ? 264.173 344.007 102.820 1.00 89.89  ? 59  ASP B O   1 
ATOM 2125 C CB  . ASP B 1 59  ? 262.952 346.427 103.009 1.00 89.89  ? 59  ASP B CB  1 
ATOM 2126 C CG  . ASP B 1 59  ? 262.421 347.827 103.250 1.00 89.89  ? 59  ASP B CG  1 
ATOM 2127 O OD1 . ASP B 1 59  ? 263.237 348.763 103.379 1.00 89.89  ? 59  ASP B OD1 1 
ATOM 2128 O OD2 . ASP B 1 59  ? 261.185 347.992 103.311 1.00 89.89  ? 59  ASP B OD2 1 
ATOM 2129 N N   . THR B 1 60  ? 266.224 344.790 102.339 1.00 98.62  ? 60  THR B N   1 
ATOM 2130 C CA  . THR B 1 60  ? 266.797 343.485 102.034 1.00 98.62  ? 60  THR B CA  1 
ATOM 2131 C C   . THR B 1 60  ? 267.336 342.863 103.315 1.00 98.62  ? 60  THR B C   1 
ATOM 2132 O O   . THR B 1 60  ? 268.247 343.412 103.943 1.00 98.62  ? 60  THR B O   1 
ATOM 2133 C CB  . THR B 1 60  ? 267.911 343.595 100.994 1.00 98.62  ? 60  THR B CB  1 
ATOM 2134 O OG1 . THR B 1 60  ? 267.380 344.125 99.773  1.00 98.62  ? 60  THR B OG1 1 
ATOM 2135 C CG2 . THR B 1 60  ? 268.510 342.226 100.724 1.00 98.62  ? 60  THR B CG2 1 
ATOM 2136 N N   . MET B 1 61  ? 266.774 341.717 103.695 1.00 96.16  ? 61  MET B N   1 
ATOM 2137 C CA  . MET B 1 61  ? 267.214 340.989 104.882 1.00 96.16  ? 61  MET B CA  1 
ATOM 2138 C C   . MET B 1 61  ? 268.326 340.043 104.451 1.00 96.16  ? 61  MET B C   1 
ATOM 2139 O O   . MET B 1 61  ? 268.094 338.870 104.153 1.00 96.16  ? 61  MET B O   1 
ATOM 2140 C CB  . MET B 1 61  ? 266.048 340.242 105.520 1.00 96.16  ? 61  MET B CB  1 
ATOM 2141 C CG  . MET B 1 61  ? 266.213 339.930 107.003 1.00 96.16  ? 61  MET B CG  1 
ATOM 2142 S SD  . MET B 1 61  ? 266.755 341.315 108.023 1.00 96.16  ? 61  MET B SD  1 
ATOM 2143 C CE  . MET B 1 61  ? 265.447 342.503 107.722 1.00 96.16  ? 61  MET B CE  1 
ATOM 2144 N N   . TYR B 1 62  ? 269.550 340.564 104.415 1.00 95.40  ? 62  TYR B N   1 
ATOM 2145 C CA  . TYR B 1 62  ? 270.689 339.800 103.932 1.00 95.40  ? 62  TYR B CA  1 
ATOM 2146 C C   . TYR B 1 62  ? 271.089 338.722 104.937 1.00 95.40  ? 62  TYR B C   1 
ATOM 2147 O O   . TYR B 1 62  ? 270.746 338.775 106.119 1.00 95.40  ? 62  TYR B O   1 
ATOM 2148 C CB  . TYR B 1 62  ? 271.884 340.717 103.661 1.00 95.40  ? 62  TYR B CB  1 
ATOM 2149 C CG  . TYR B 1 62  ? 271.904 341.367 102.292 1.00 95.40  ? 62  TYR B CG  1 
ATOM 2150 C CD1 . TYR B 1 62  ? 271.975 342.748 102.159 1.00 95.40  ? 62  TYR B CD1 1 
ATOM 2151 C CD2 . TYR B 1 62  ? 271.870 340.600 101.136 1.00 95.40  ? 62  TYR B CD2 1 
ATOM 2152 C CE1 . TYR B 1 62  ? 272.002 343.348 100.910 1.00 95.40  ? 62  TYR B CE1 1 
ATOM 2153 C CE2 . TYR B 1 62  ? 271.896 341.187 99.884  1.00 95.40  ? 62  TYR B CE2 1 
ATOM 2154 C CZ  . TYR B 1 62  ? 271.961 342.561 99.778  1.00 95.40  ? 62  TYR B CZ  1 
ATOM 2155 O OH  . TYR B 1 62  ? 271.985 343.147 98.535  1.00 95.40  ? 62  TYR B OH  1 
ATOM 2156 N N   . TYR B 1 63  ? 271.822 337.726 104.442 1.00 89.72  ? 63  TYR B N   1 
ATOM 2157 C CA  . TYR B 1 63  ? 272.377 336.650 105.265 1.00 89.72  ? 63  TYR B CA  1 
ATOM 2158 C C   . TYR B 1 63  ? 273.888 336.706 105.082 1.00 89.72  ? 63  TYR B C   1 
ATOM 2159 O O   . TYR B 1 63  ? 274.451 335.960 104.277 1.00 89.72  ? 63  TYR B O   1 
ATOM 2160 C CB  . TYR B 1 63  ? 271.814 335.288 104.869 1.00 89.72  ? 63  TYR B CB  1 
ATOM 2161 C CG  . TYR B 1 63  ? 270.475 334.962 105.487 1.00 89.72  ? 63  TYR B CG  1 
ATOM 2162 C CD1 . TYR B 1 63  ? 270.153 335.399 106.769 1.00 89.72  ? 63  TYR B CD1 1 
ATOM 2163 C CD2 . TYR B 1 63  ? 269.537 334.207 104.795 1.00 89.72  ? 63  TYR B CD2 1 
ATOM 2164 C CE1 . TYR B 1 63  ? 268.926 335.098 107.340 1.00 89.72  ? 63  TYR B CE1 1 
ATOM 2165 C CE2 . TYR B 1 63  ? 268.311 333.897 105.357 1.00 89.72  ? 63  TYR B CE2 1 
ATOM 2166 C CZ  . TYR B 1 63  ? 268.011 334.343 106.628 1.00 89.72  ? 63  TYR B CZ  1 
ATOM 2167 O OH  . TYR B 1 63  ? 266.791 334.037 107.183 1.00 89.72  ? 63  TYR B OH  1 
ATOM 2168 N N   . LEU B 1 64  ? 274.544 337.571 105.852 1.00 78.34  ? 64  LEU B N   1 
ATOM 2169 C CA  . LEU B 1 64  ? 275.956 337.881 105.639 1.00 78.34  ? 64  LEU B CA  1 
ATOM 2170 C C   . LEU B 1 64  ? 276.805 336.852 106.369 1.00 78.34  ? 64  LEU B C   1 
ATOM 2171 O O   . LEU B 1 64  ? 277.251 337.067 107.496 1.00 78.34  ? 64  LEU B O   1 
ATOM 2172 C CB  . LEU B 1 64  ? 276.269 339.294 106.110 1.00 78.34  ? 64  LEU B CB  1 
ATOM 2173 C CG  . LEU B 1 64  ? 275.704 340.468 105.314 1.00 78.34  ? 64  LEU B CG  1 
ATOM 2174 C CD1 . LEU B 1 64  ? 276.458 341.729 105.687 1.00 78.34  ? 64  LEU B CD1 1 
ATOM 2175 C CD2 . LEU B 1 64  ? 275.783 340.211 103.814 1.00 78.34  ? 64  LEU B CD2 1 
ATOM 2176 N N   . THR B 1 65  ? 277.044 335.720 105.707 1.00 77.06  ? 65  THR B N   1 
ATOM 2177 C CA  . THR B 1 65  ? 277.969 334.701 106.203 1.00 77.06  ? 65  THR B CA  1 
ATOM 2178 C C   . THR B 1 65  ? 279.389 335.169 105.887 1.00 77.06  ? 65  THR B C   1 
ATOM 2179 O O   . THR B 1 65  ? 280.022 334.760 104.911 1.00 77.06  ? 65  THR B O   1 
ATOM 2180 C CB  . THR B 1 65  ? 277.671 333.347 105.576 1.00 77.06  ? 65  THR B CB  1 
ATOM 2181 O OG1 . THR B 1 65  ? 278.265 333.296 104.277 1.00 77.06  ? 65  THR B OG1 1 
ATOM 2182 C CG2 . THR B 1 65  ? 276.171 333.137 105.434 1.00 77.06  ? 65  THR B CG2 1 
ATOM 2183 N N   . LEU B 1 66  ? 279.889 336.058 106.736 1.00 78.24  ? 66  LEU B N   1 
ATOM 2184 C CA  . LEU B 1 66  ? 281.156 336.741 106.520 1.00 78.24  ? 66  LEU B CA  1 
ATOM 2185 C C   . LEU B 1 66  ? 282.211 336.175 107.461 1.00 78.24  ? 66  LEU B C   1 
ATOM 2186 O O   . LEU B 1 66  ? 281.951 335.996 108.654 1.00 78.24  ? 66  LEU B O   1 
ATOM 2187 C CB  . LEU B 1 66  ? 280.959 338.250 106.710 1.00 78.24  ? 66  LEU B CB  1 
ATOM 2188 C CG  . LEU B 1 66  ? 280.566 338.863 108.065 1.00 78.24  ? 66  LEU B CG  1 
ATOM 2189 C CD1 . LEU B 1 66  ? 281.766 339.366 108.859 1.00 78.24  ? 66  LEU B CD1 1 
ATOM 2190 C CD2 . LEU B 1 66  ? 279.494 339.935 107.930 1.00 78.24  ? 66  LEU B CD2 1 
ATOM 2191 N N   . GLU B 1 67  ? 283.382 335.846 106.923 1.00 83.71  ? 67  GLU B N   1 
ATOM 2192 C CA  . GLU B 1 67  ? 284.476 335.374 107.761 1.00 83.71  ? 67  GLU B CA  1 
ATOM 2193 C C   . GLU B 1 67  ? 285.268 336.584 108.250 1.00 83.71  ? 67  GLU B C   1 
ATOM 2194 O O   . GLU B 1 67  ? 285.633 337.464 107.461 1.00 83.71  ? 67  GLU B O   1 
ATOM 2195 C CB  . GLU B 1 67  ? 285.340 334.330 107.038 1.00 83.71  ? 67  GLU B CB  1 
ATOM 2196 C CG  . GLU B 1 67  ? 286.192 334.755 105.847 1.00 83.71  ? 67  GLU B CG  1 
ATOM 2197 C CD  . GLU B 1 67  ? 287.573 335.226 106.249 1.00 83.71  ? 67  GLU B CD  1 
ATOM 2198 O OE1 . GLU B 1 67  ? 288.163 336.046 105.520 1.00 83.71  ? 67  GLU B OE1 1 
ATOM 2199 O OE2 . GLU B 1 67  ? 288.067 334.783 107.309 1.00 83.71  ? 67  GLU B OE2 1 
ATOM 2200 N N   . ALA B 1 68  ? 285.462 336.662 109.564 1.00 81.82  ? 68  ALA B N   1 
ATOM 2201 C CA  . ALA B 1 68  ? 286.079 337.825 110.184 1.00 81.82  ? 68  ALA B CA  1 
ATOM 2202 C C   . ALA B 1 68  ? 286.815 337.380 111.436 1.00 81.82  ? 68  ALA B C   1 
ATOM 2203 O O   . ALA B 1 68  ? 286.322 336.524 112.176 1.00 81.82  ? 68  ALA B O   1 
ATOM 2204 C CB  . ALA B 1 68  ? 285.032 338.888 110.515 1.00 81.82  ? 68  ALA B CB  1 
ATOM 2205 N N   . LYS B 1 69  ? 287.980 337.974 111.677 1.00 81.01  ? 69  LYS B N   1 
ATOM 2206 C CA  . LYS B 1 69  ? 288.981 337.387 112.559 1.00 81.01  ? 69  LYS B CA  1 
ATOM 2207 C C   . LYS B 1 69  ? 288.910 337.984 113.959 1.00 81.01  ? 69  LYS B C   1 
ATOM 2208 O O   . LYS B 1 69  ? 289.352 339.115 114.185 1.00 81.01  ? 69  LYS B O   1 
ATOM 2209 C CB  . LYS B 1 69  ? 290.376 337.582 111.982 1.00 81.01  ? 69  LYS B CB  1 
ATOM 2210 C CG  . LYS B 1 69  ? 290.484 337.390 110.491 1.00 81.01  ? 69  LYS B CG  1 
ATOM 2211 C CD  . LYS B 1 69  ? 291.555 338.315 109.966 1.00 81.01  ? 69  LYS B CD  1 
ATOM 2212 C CE  . LYS B 1 69  ? 291.488 338.472 108.476 1.00 81.01  ? 69  LYS B CE  1 
ATOM 2213 N NZ  . LYS B 1 69  ? 292.039 339.800 108.100 1.00 81.01  ? 69  LYS B NZ  1 
ATOM 2214 N N   . ASP B 1 70  ? 288.377 337.212 114.901 1.00 76.89  ? 70  ASP B N   1 
ATOM 2215 C CA  . ASP B 1 70  ? 288.597 337.452 116.324 1.00 76.89  ? 70  ASP B CA  1 
ATOM 2216 C C   . ASP B 1 70  ? 289.823 336.633 116.706 1.00 76.89  ? 70  ASP B C   1 
ATOM 2217 O O   . ASP B 1 70  ? 289.741 335.414 116.885 1.00 76.89  ? 70  ASP B O   1 
ATOM 2218 C CB  . ASP B 1 70  ? 287.369 337.055 117.139 1.00 76.89  ? 70  ASP B CB  1 
ATOM 2219 C CG  . ASP B 1 70  ? 287.383 337.629 118.546 1.00 76.89  ? 70  ASP B CG  1 
ATOM 2220 O OD1 . ASP B 1 70  ? 286.343 337.522 119.228 1.00 76.89  ? 70  ASP B OD1 1 
ATOM 2221 O OD2 . ASP B 1 70  ? 288.407 338.202 118.967 1.00 76.89  ? 70  ASP B OD2 1 
ATOM 2222 N N   . GLY B 1 71  ? 290.966 337.300 116.815 1.00 69.66  ? 71  GLY B N   1 
ATOM 2223 C CA  . GLY B 1 71  ? 292.213 336.622 117.113 1.00 69.66  ? 71  GLY B CA  1 
ATOM 2224 C C   . GLY B 1 71  ? 293.092 336.330 115.919 1.00 69.66  ? 71  GLY B C   1 
ATOM 2225 O O   . GLY B 1 71  ? 294.118 335.657 116.074 1.00 69.66  ? 71  GLY B O   1 
ATOM 2226 N N   . GLY B 1 72  ? 292.725 336.811 114.732 1.00 74.30  ? 72  GLY B N   1 
ATOM 2227 C CA  . GLY B 1 72  ? 293.540 336.651 113.550 1.00 74.30  ? 72  GLY B CA  1 
ATOM 2228 C C   . GLY B 1 72  ? 293.135 335.523 112.624 1.00 74.30  ? 72  GLY B C   1 
ATOM 2229 O O   . GLY B 1 72  ? 293.585 335.501 111.471 1.00 74.30  ? 72  GLY B O   1 
ATOM 2230 N N   . LYS B 1 73  ? 292.277 334.609 113.065 1.00 76.46  ? 73  LYS B N   1 
ATOM 2231 C CA  . LYS B 1 73  ? 292.003 333.398 112.307 1.00 76.46  ? 73  LYS B CA  1 
ATOM 2232 C C   . LYS B 1 73  ? 290.705 333.508 111.514 1.00 76.46  ? 73  LYS B C   1 
ATOM 2233 O O   . LYS B 1 73  ? 289.816 334.301 111.826 1.00 76.46  ? 73  LYS B O   1 
ATOM 2234 C CB  . LYS B 1 73  ? 291.952 332.182 113.233 1.00 76.46  ? 73  LYS B CB  1 
ATOM 2235 C CG  . LYS B 1 73  ? 293.286 331.873 113.882 1.00 76.46  ? 73  LYS B CG  1 
ATOM 2236 C CD  . LYS B 1 73  ? 294.334 331.592 112.816 1.00 76.46  ? 73  LYS B CD  1 
ATOM 2237 C CE  . LYS B 1 73  ? 294.428 330.111 112.509 1.00 76.46  ? 73  LYS B CE  1 
ATOM 2238 N NZ  . LYS B 1 73  ? 295.735 329.730 111.916 1.00 76.46  ? 73  LYS B NZ  1 
ATOM 2239 N N   . LYS B 1 74  ? 290.610 332.674 110.477 1.00 77.84  ? 74  LYS B N   1 
ATOM 2240 C CA  . LYS B 1 74  ? 289.501 332.713 109.522 1.00 77.84  ? 74  LYS B CA  1 
ATOM 2241 C C   . LYS B 1 74  ? 288.324 331.907 110.068 1.00 77.84  ? 74  LYS B C   1 
ATOM 2242 O O   . LYS B 1 74  ? 288.040 330.786 109.641 1.00 77.84  ? 74  LYS B O   1 
ATOM 2243 C CB  . LYS B 1 74  ? 289.954 332.184 108.167 1.00 77.84  ? 74  LYS B CB  1 
ATOM 2244 C CG  . LYS B 1 74  ? 291.248 332.798 107.664 1.00 77.84  ? 74  LYS B CG  1 
ATOM 2245 C CD  . LYS B 1 74  ? 291.569 332.333 106.258 1.00 77.84  ? 74  LYS B CD  1 
ATOM 2246 C CE  . LYS B 1 74  ? 292.110 333.466 105.409 1.00 77.84  ? 74  LYS B CE  1 
ATOM 2247 N NZ  . LYS B 1 74  ? 291.142 334.591 105.322 1.00 77.84  ? 74  LYS B NZ  1 
ATOM 2248 N N   . LYS B 1 75  ? 287.629 332.497 111.034 1.00 79.53  ? 75  LYS B N   1 
ATOM 2249 C CA  . LYS B 1 75  ? 286.393 331.942 111.568 1.00 79.53  ? 75  LYS B CA  1 
ATOM 2250 C C   . LYS B 1 75  ? 285.210 332.764 111.066 1.00 79.53  ? 75  LYS B C   1 
ATOM 2251 O O   . LYS B 1 75  ? 285.358 333.910 110.635 1.00 79.53  ? 75  LYS B O   1 
ATOM 2252 C CB  . LYS B 1 75  ? 286.439 331.898 113.099 1.00 79.53  ? 75  LYS B CB  1 
ATOM 2253 C CG  . LYS B 1 75  ? 286.524 333.259 113.760 1.00 79.53  ? 75  LYS B CG  1 
ATOM 2254 C CD  . LYS B 1 75  ? 286.046 333.194 115.196 1.00 79.53  ? 75  LYS B CD  1 
ATOM 2255 C CE  . LYS B 1 75  ? 284.546 333.377 115.299 1.00 79.53  ? 75  LYS B CE  1 
ATOM 2256 N NZ  . LYS B 1 75  ? 284.122 333.591 116.713 1.00 79.53  ? 75  LYS B NZ  1 
ATOM 2257 N N   . LEU B 1 76  ? 284.023 332.169 111.139 1.00 83.44  ? 76  LEU B N   1 
ATOM 2258 C CA  . LEU B 1 76  ? 282.849 332.667 110.437 1.00 83.44  ? 76  LEU B CA  1 
ATOM 2259 C C   . LEU B 1 76  ? 281.942 333.477 111.357 1.00 83.44  ? 76  LEU B C   1 
ATOM 2260 O O   . LEU B 1 76  ? 281.811 333.190 112.549 1.00 83.44  ? 76  LEU B O   1 
ATOM 2261 C CB  . LEU B 1 76  ? 282.050 331.510 109.824 1.00 83.44  ? 76  LEU B CB  1 
ATOM 2262 C CG  . LEU B 1 76  ? 281.214 331.813 108.578 1.00 83.44  ? 76  LEU B CG  1 
ATOM 2263 C CD1 . LEU B 1 76  ? 282.037 332.557 107.545 1.00 83.44  ? 76  LEU B CD1 1 
ATOM 2264 C CD2 . LEU B 1 76  ? 280.633 330.540 107.984 1.00 83.44  ? 76  LEU B CD2 1 
ATOM 2265 N N   . TYR B 1 77  ? 281.321 334.500 110.772 1.00 78.45  ? 77  TYR B N   1 
ATOM 2266 C CA  . TYR B 1 77  ? 280.321 335.336 111.431 1.00 78.45  ? 77  TYR B CA  1 
ATOM 2267 C C   . TYR B 1 77  ? 279.121 335.435 110.505 1.00 78.45  ? 77  TYR B C   1 
ATOM 2268 O O   . TYR B 1 77  ? 279.116 336.264 109.591 1.00 78.45  ? 77  TYR B O   1 
ATOM 2269 C CB  . TYR B 1 77  ? 280.869 336.729 111.733 1.00 78.45  ? 77  TYR B CB  1 
ATOM 2270 C CG  . TYR B 1 77  ? 281.700 336.862 112.985 1.00 78.45  ? 77  TYR B CG  1 
ATOM 2271 C CD1 . TYR B 1 77  ? 281.543 335.991 114.058 1.00 78.45  ? 77  TYR B CD1 1 
ATOM 2272 C CD2 . TYR B 1 77  ? 282.657 337.856 113.086 1.00 78.45  ? 77  TYR B CD2 1 
ATOM 2273 C CE1 . TYR B 1 77  ? 282.299 336.133 115.204 1.00 78.45  ? 77  TYR B CE1 1 
ATOM 2274 C CE2 . TYR B 1 77  ? 283.425 337.997 114.219 1.00 78.45  ? 77  TYR B CE2 1 
ATOM 2275 C CZ  . TYR B 1 77  ? 283.250 337.130 115.273 1.00 78.45  ? 77  TYR B CZ  1 
ATOM 2276 O OH  . TYR B 1 77  ? 284.019 337.281 116.404 1.00 78.45  ? 77  TYR B OH  1 
ATOM 2277 N N   . GLU B 1 78  ? 278.112 334.596 110.728 1.00 76.14  ? 78  GLU B N   1 
ATOM 2278 C CA  . GLU B 1 78  ? 276.850 334.739 110.015 1.00 76.14  ? 78  GLU B CA  1 
ATOM 2279 C C   . GLU B 1 78  ? 276.147 335.988 110.532 1.00 76.14  ? 78  GLU B C   1 
ATOM 2280 O O   . GLU B 1 78  ? 275.787 336.059 111.712 1.00 76.14  ? 78  GLU B O   1 
ATOM 2281 C CB  . GLU B 1 78  ? 275.975 333.503 110.212 1.00 76.14  ? 78  GLU B CB  1 
ATOM 2282 C CG  . GLU B 1 78  ? 275.111 333.130 109.008 1.00 76.14  ? 78  GLU B CG  1 
ATOM 2283 C CD  . GLU B 1 78  ? 273.919 334.049 108.813 1.00 76.14  ? 78  GLU B CD  1 
ATOM 2284 O OE1 . GLU B 1 78  ? 273.158 334.268 109.778 1.00 76.14  ? 78  GLU B OE1 1 
ATOM 2285 O OE2 . GLU B 1 78  ? 273.743 334.556 107.689 1.00 76.14  ? 78  GLU B OE2 1 
ATOM 2286 N N   . ALA B 1 79  ? 275.970 336.979 109.663 1.00 75.04  ? 79  ALA B N   1 
ATOM 2287 C CA  . ALA B 1 79  ? 275.330 338.229 110.036 1.00 75.04  ? 79  ALA B CA  1 
ATOM 2288 C C   . ALA B 1 79  ? 274.037 338.419 109.253 1.00 75.04  ? 79  ALA B C   1 
ATOM 2289 O O   . ALA B 1 79  ? 273.764 337.717 108.275 1.00 75.04  ? 79  ALA B O   1 
ATOM 2290 C CB  . ALA B 1 79  ? 276.260 339.424 109.805 1.00 75.04  ? 79  ALA B CB  1 
ATOM 2291 N N   . LYS B 1 80  ? 273.239 339.388 109.700 1.00 78.62  ? 80  LYS B N   1 
ATOM 2292 C CA  . LYS B 1 80  ? 271.941 339.675 109.101 1.00 78.62  ? 80  LYS B CA  1 
ATOM 2293 C C   . LYS B 1 80  ? 271.647 341.155 109.278 1.00 78.62  ? 80  LYS B C   1 
ATOM 2294 O O   . LYS B 1 80  ? 271.598 341.648 110.408 1.00 78.62  ? 80  LYS B O   1 
ATOM 2295 C CB  . LYS B 1 80  ? 270.839 338.820 109.735 1.00 78.62  ? 80  LYS B CB  1 
ATOM 2296 C CG  . LYS B 1 80  ? 269.457 339.009 109.140 1.00 78.62  ? 80  LYS B CG  1 
ATOM 2297 C CD  . LYS B 1 80  ? 268.390 338.818 110.195 1.00 78.62  ? 80  LYS B CD  1 
ATOM 2298 C CE  . LYS B 1 80  ? 268.541 339.830 111.318 1.00 78.62  ? 80  LYS B CE  1 
ATOM 2299 N NZ  . LYS B 1 80  ? 268.361 341.226 110.838 1.00 78.62  ? 80  LYS B NZ  1 
ATOM 2300 N N   . VAL B 1 81  ? 271.456 341.860 108.166 1.00 86.85  ? 81  VAL B N   1 
ATOM 2301 C CA  . VAL B 1 81  ? 271.270 343.303 108.180 1.00 86.85  ? 81  VAL B CA  1 
ATOM 2302 C C   . VAL B 1 81  ? 269.923 343.642 107.561 1.00 86.85  ? 81  VAL B C   1 
ATOM 2303 O O   . VAL B 1 81  ? 269.367 342.875 106.768 1.00 86.85  ? 81  VAL B O   1 
ATOM 2304 C CB  . VAL B 1 81  ? 272.404 344.035 107.429 1.00 86.85  ? 81  VAL B CB  1 
ATOM 2305 C CG1 . VAL B 1 81  ? 273.698 343.921 108.192 1.00 86.85  ? 81  VAL B CG1 1 
ATOM 2306 C CG2 . VAL B 1 81  ? 272.566 343.477 106.032 1.00 86.85  ? 81  VAL B CG2 1 
ATOM 2307 N N   . TRP B 1 82  ? 269.401 344.807 107.933 1.00 101.41 ? 82  TRP B N   1 
ATOM 2308 C CA  . TRP B 1 82  ? 268.206 345.380 107.322 1.00 101.41 ? 82  TRP B CA  1 
ATOM 2309 C C   . TRP B 1 82  ? 268.654 346.565 106.477 1.00 101.41 ? 82  TRP B C   1 
ATOM 2310 O O   . TRP B 1 82  ? 268.920 347.646 107.011 1.00 101.41 ? 82  TRP B O   1 
ATOM 2311 C CB  . TRP B 1 82  ? 267.190 345.803 108.385 1.00 101.41 ? 82  TRP B CB  1 
ATOM 2312 C CG  . TRP B 1 82  ? 265.780 346.080 107.879 1.00 101.41 ? 82  TRP B CG  1 
ATOM 2313 C CD1 . TRP B 1 82  ? 265.419 346.631 106.677 1.00 101.41 ? 82  TRP B CD1 1 
ATOM 2314 C CD2 . TRP B 1 82  ? 264.555 345.823 108.578 1.00 101.41 ? 82  TRP B CD2 1 
ATOM 2315 N NE1 . TRP B 1 82  ? 264.054 346.726 106.588 1.00 101.41 ? 82  TRP B NE1 1 
ATOM 2316 C CE2 . TRP B 1 82  ? 263.499 346.237 107.740 1.00 101.41 ? 82  TRP B CE2 1 
ATOM 2317 C CE3 . TRP B 1 82  ? 264.248 345.278 109.828 1.00 101.41 ? 82  TRP B CE3 1 
ATOM 2318 C CZ2 . TRP B 1 82  ? 262.162 346.125 108.113 1.00 101.41 ? 82  TRP B CZ2 1 
ATOM 2319 C CZ3 . TRP B 1 82  ? 262.918 345.167 110.197 1.00 101.41 ? 82  TRP B CZ3 1 
ATOM 2320 C CH2 . TRP B 1 82  ? 261.893 345.589 109.342 1.00 101.41 ? 82  TRP B CH2 1 
ATOM 2321 N N   . VAL B 1 83  ? 268.738 346.360 105.166 1.00 92.19  ? 83  VAL B N   1 
ATOM 2322 C CA  . VAL B 1 83  ? 268.991 347.448 104.226 1.00 92.19  ? 83  VAL B CA  1 
ATOM 2323 C C   . VAL B 1 83  ? 267.927 347.424 103.136 1.00 92.19  ? 83  VAL B C   1 
ATOM 2324 O O   . VAL B 1 83  ? 267.370 348.460 102.771 1.00 92.19  ? 83  VAL B O   1 
ATOM 2325 C CB  . VAL B 1 83  ? 270.402 347.367 103.610 1.00 92.19  ? 83  VAL B CB  1 
ATOM 2326 C CG1 . VAL B 1 83  ? 271.471 347.617 104.662 1.00 92.19  ? 83  VAL B CG1 1 
ATOM 2327 C CG2 . VAL B 1 83  ? 270.604 346.023 102.945 1.00 92.19  ? 83  VAL B CG2 1 
ATOM 2328 N N   . GLY B 1 89  ? 271.860 353.033 94.076  1.00 74.53  ? 89  GLY B N   1 
ATOM 2329 C CA  . GLY B 1 89  ? 270.534 353.591 94.269  1.00 74.53  ? 89  GLY B CA  1 
ATOM 2330 C C   . GLY B 1 89  ? 270.139 353.686 95.729  1.00 74.53  ? 89  GLY B C   1 
ATOM 2331 O O   . GLY B 1 89  ? 270.889 354.210 96.551  1.00 74.53  ? 89  GLY B O   1 
ATOM 2332 N N   . LEU B 1 90  ? 268.952 353.170 96.053  1.00 86.38  ? 90  LEU B N   1 
ATOM 2333 C CA  . LEU B 1 90  ? 268.459 353.194 97.424  1.00 86.38  ? 90  LEU B CA  1 
ATOM 2334 C C   . LEU B 1 90  ? 269.143 352.172 98.321  1.00 86.38  ? 90  LEU B C   1 
ATOM 2335 O O   . LEU B 1 90  ? 269.054 352.295 99.547  1.00 86.38  ? 90  LEU B O   1 
ATOM 2336 C CB  . LEU B 1 90  ? 266.937 352.983 97.434  1.00 86.38  ? 90  LEU B CB  1 
ATOM 2337 C CG  . LEU B 1 90  ? 266.287 351.724 96.837  1.00 86.38  ? 90  LEU B CG  1 
ATOM 2338 C CD1 . LEU B 1 90  ? 266.100 350.586 97.846  1.00 86.38  ? 90  LEU B CD1 1 
ATOM 2339 C CD2 . LEU B 1 90  ? 264.960 352.078 96.179  1.00 86.38  ? 90  LEU B CD2 1 
ATOM 2340 N N   . ASN B 1 91  ? 269.815 351.171 97.747  1.00 89.30  ? 91  ASN B N   1 
ATOM 2341 C CA  . ASN B 1 91  ? 270.464 350.143 98.551  1.00 89.30  ? 91  ASN B CA  1 
ATOM 2342 C C   . ASN B 1 91  ? 271.734 350.663 99.219  1.00 89.30  ? 91  ASN B C   1 
ATOM 2343 O O   . ASN B 1 91  ? 272.139 350.131 100.258 1.00 89.30  ? 91  ASN B O   1 
ATOM 2344 C CB  . ASN B 1 91  ? 270.760 348.922 97.671  1.00 89.30  ? 91  ASN B CB  1 
ATOM 2345 C CG  . ASN B 1 91  ? 271.147 347.690 98.473  1.00 89.30  ? 91  ASN B CG  1 
ATOM 2346 O OD1 . ASN B 1 91  ? 272.268 347.576 98.965  1.00 89.30  ? 91  ASN B OD1 1 
ATOM 2347 N ND2 . ASN B 1 91  ? 270.211 346.758 98.604  1.00 89.30  ? 91  ASN B ND2 1 
ATOM 2348 N N   . LYS B 1 92  ? 272.358 351.698 98.653  1.00 94.86  ? 92  LYS B N   1 
ATOM 2349 C CA  . LYS B 1 92  ? 273.489 352.350 99.306  1.00 94.86  ? 92  LYS B CA  1 
ATOM 2350 C C   . LYS B 1 92  ? 273.023 353.362 100.348 1.00 94.86  ? 92  LYS B C   1 
ATOM 2351 O O   . LYS B 1 92  ? 273.496 353.352 101.490 1.00 94.86  ? 92  LYS B O   1 
ATOM 2352 C CB  . LYS B 1 92  ? 274.373 353.040 98.264  1.00 94.86  ? 92  LYS B CB  1 
ATOM 2353 C CG  . LYS B 1 92  ? 275.639 352.289 97.878  1.00 94.86  ? 92  LYS B CG  1 
ATOM 2354 C CD  . LYS B 1 92  ? 276.425 351.844 99.100  1.00 94.86  ? 92  LYS B CD  1 
ATOM 2355 C CE  . LYS B 1 92  ? 277.614 350.985 98.703  1.00 94.86  ? 92  LYS B CE  1 
ATOM 2356 N NZ  . LYS B 1 92  ? 278.177 350.248 99.866  1.00 94.86  ? 92  LYS B NZ  1 
ATOM 2357 N N   . TYR B 1 93  ? 272.096 354.240 99.971  1.00 102.05 ? 93  TYR B N   1 
ATOM 2358 C CA  . TYR B 1 93  ? 271.675 355.346 100.830 1.00 102.05 ? 93  TYR B CA  1 
ATOM 2359 C C   . TYR B 1 93  ? 270.393 354.971 101.572 1.00 102.05 ? 93  TYR B C   1 
ATOM 2360 O O   . TYR B 1 93  ? 269.284 355.380 101.225 1.00 102.05 ? 93  TYR B O   1 
ATOM 2361 C CB  . TYR B 1 93  ? 271.497 356.620 100.006 1.00 102.05 ? 93  TYR B CB  1 
ATOM 2362 C CG  . TYR B 1 93  ? 272.725 357.032 99.220  1.00 102.05 ? 93  TYR B CG  1 
ATOM 2363 C CD1 . TYR B 1 93  ? 272.902 356.624 97.900  1.00 102.05 ? 93  TYR B CD1 1 
ATOM 2364 C CD2 . TYR B 1 93  ? 273.708 357.826 99.799  1.00 102.05 ? 93  TYR B CD2 1 
ATOM 2365 C CE1 . TYR B 1 93  ? 274.024 356.997 97.180  1.00 102.05 ? 93  TYR B CE1 1 
ATOM 2366 C CE2 . TYR B 1 93  ? 274.834 358.204 99.087  1.00 102.05 ? 93  TYR B CE2 1 
ATOM 2367 C CZ  . TYR B 1 93  ? 274.986 357.787 97.779  1.00 102.05 ? 93  TYR B CZ  1 
ATOM 2368 O OH  . TYR B 1 93  ? 276.103 358.161 97.067  1.00 102.05 ? 93  TYR B OH  1 
ATOM 2369 N N   . ASN B 1 94  ? 270.574 354.172 102.621 1.00 96.60  ? 94  ASN B N   1 
ATOM 2370 C CA  . ASN B 1 94  ? 269.478 353.752 103.484 1.00 96.60  ? 94  ASN B CA  1 
ATOM 2371 C C   . ASN B 1 94  ? 270.043 353.429 104.862 1.00 96.60  ? 94  ASN B C   1 
ATOM 2372 O O   . ASN B 1 94  ? 271.238 353.596 105.120 1.00 96.60  ? 94  ASN B O   1 
ATOM 2373 C CB  . ASN B 1 94  ? 268.729 352.558 102.884 1.00 96.60  ? 94  ASN B CB  1 
ATOM 2374 C CG  . ASN B 1 94  ? 269.654 351.422 102.503 1.00 96.60  ? 94  ASN B CG  1 
ATOM 2375 O OD1 . ASN B 1 94  ? 270.874 351.581 102.465 1.00 96.60  ? 94  ASN B OD1 1 
ATOM 2376 N ND2 . ASN B 1 94  ? 269.075 350.268 102.201 1.00 96.60  ? 94  ASN B ND2 1 
ATOM 2377 N N   . PHE B 1 95  ? 269.171 352.958 105.750 1.00 95.56  ? 95  PHE B N   1 
ATOM 2378 C CA  . PHE B 1 95  ? 269.601 352.628 107.102 1.00 95.56  ? 95  PHE B CA  1 
ATOM 2379 C C   . PHE B 1 95  ? 270.299 351.273 107.119 1.00 95.56  ? 95  PHE B C   1 
ATOM 2380 O O   . PHE B 1 95  ? 269.839 350.316 106.492 1.00 95.56  ? 95  PHE B O   1 
ATOM 2381 C CB  . PHE B 1 95  ? 268.414 352.636 108.073 1.00 95.56  ? 95  PHE B CB  1 
ATOM 2382 C CG  . PHE B 1 95  ? 267.112 352.150 107.479 1.00 95.56  ? 95  PHE B CG  1 
ATOM 2383 C CD1 . PHE B 1 95  ? 266.173 353.054 106.994 1.00 95.56  ? 95  PHE B CD1 1 
ATOM 2384 C CD2 . PHE B 1 95  ? 266.811 350.797 107.444 1.00 95.56  ? 95  PHE B CD2 1 
ATOM 2385 C CE1 . PHE B 1 95  ? 264.973 352.613 106.462 1.00 95.56  ? 95  PHE B CE1 1 
ATOM 2386 C CE2 . PHE B 1 95  ? 265.611 350.351 106.913 1.00 95.56  ? 95  PHE B CE2 1 
ATOM 2387 C CZ  . PHE B 1 95  ? 264.693 351.261 106.423 1.00 95.56  ? 95  PHE B CZ  1 
ATOM 2388 N N   . LYS B 1 96  ? 271.433 351.205 107.814 1.00 86.15  ? 96  LYS B N   1 
ATOM 2389 C CA  . LYS B 1 96  ? 272.192 349.974 107.994 1.00 86.15  ? 96  LYS B CA  1 
ATOM 2390 C C   . LYS B 1 96  ? 272.477 349.808 109.480 1.00 86.15  ? 96  LYS B C   1 
ATOM 2391 O O   . LYS B 1 96  ? 273.008 350.723 110.120 1.00 86.15  ? 96  LYS B O   1 
ATOM 2392 C CB  . LYS B 1 96  ? 273.487 350.003 107.175 1.00 86.15  ? 96  LYS B CB  1 
ATOM 2393 C CG  . LYS B 1 96  ? 274.637 349.180 107.742 1.00 86.15  ? 96  LYS B CG  1 
ATOM 2394 C CD  . LYS B 1 96  ? 274.488 347.697 107.468 1.00 86.15  ? 96  LYS B CD  1 
ATOM 2395 C CE  . LYS B 1 96  ? 275.803 346.965 107.696 1.00 86.15  ? 96  LYS B CE  1 
ATOM 2396 N NZ  . LYS B 1 96  ? 276.193 346.948 109.130 1.00 86.15  ? 96  LYS B NZ  1 
ATOM 2397 N N   . GLU B 1 97  ? 272.120 348.645 110.023 1.00 85.58  ? 97  GLU B N   1 
ATOM 2398 C CA  . GLU B 1 97  ? 272.190 348.404 111.457 1.00 85.58  ? 97  GLU B CA  1 
ATOM 2399 C C   . GLU B 1 97  ? 272.138 346.899 111.685 1.00 85.58  ? 97  GLU B C   1 
ATOM 2400 O O   . GLU B 1 97  ? 271.425 346.185 110.974 1.00 85.58  ? 97  GLU B O   1 
ATOM 2401 C CB  . GLU B 1 97  ? 271.045 349.132 112.183 1.00 85.58  ? 97  GLU B CB  1 
ATOM 2402 C CG  . GLU B 1 97  ? 271.274 349.437 113.656 1.00 85.58  ? 97  GLU B CG  1 
ATOM 2403 C CD  . GLU B 1 97  ? 271.047 348.244 114.548 1.00 85.58  ? 97  GLU B CD  1 
ATOM 2404 O OE1 . GLU B 1 97  ? 271.626 348.204 115.653 1.00 85.58  ? 97  GLU B OE1 1 
ATOM 2405 O OE2 . GLU B 1 97  ? 270.259 347.361 114.153 1.00 85.58  ? 97  GLU B OE2 1 
ATOM 2406 N N   . LEU B 1 98  ? 272.897 346.426 112.670 1.00 83.79  ? 98  LEU B N   1 
ATOM 2407 C CA  . LEU B 1 98  ? 272.991 345.004 112.966 1.00 83.79  ? 98  LEU B CA  1 
ATOM 2408 C C   . LEU B 1 98  ? 272.029 344.597 114.070 1.00 83.79  ? 98  LEU B C   1 
ATOM 2409 O O   . LEU B 1 98  ? 271.952 345.242 115.119 1.00 83.79  ? 98  LEU B O   1 
ATOM 2410 C CB  . LEU B 1 98  ? 274.405 344.604 113.389 1.00 83.79  ? 98  LEU B CB  1 
ATOM 2411 C CG  . LEU B 1 98  ? 275.596 344.895 112.492 1.00 83.79  ? 98  LEU B CG  1 
ATOM 2412 C CD1 . LEU B 1 98  ? 276.869 344.765 113.296 1.00 83.79  ? 98  LEU B CD1 1 
ATOM 2413 C CD2 . LEU B 1 98  ? 275.594 343.918 111.350 1.00 83.79  ? 98  LEU B CD2 1 
ATOM 2414 N N   . GLN B 1 99  ? 271.322 343.494 113.833 1.00 79.69  ? 99  GLN B N   1 
ATOM 2415 C CA  . GLN B 1 99  ? 270.605 342.782 114.875 1.00 79.69  ? 99  GLN B CA  1 
ATOM 2416 C C   . GLN B 1 99  ? 271.081 341.346 115.038 1.00 79.69  ? 99  GLN B C   1 
ATOM 2417 O O   . GLN B 1 99  ? 270.650 340.673 115.983 1.00 79.69  ? 99  GLN B O   1 
ATOM 2418 C CB  . GLN B 1 99  ? 269.096 342.783 114.587 1.00 79.69  ? 99  GLN B CB  1 
ATOM 2419 C CG  . GLN B 1 99  ? 268.377 344.031 115.053 1.00 79.69  ? 99  GLN B CG  1 
ATOM 2420 C CD  . GLN B 1 99  ? 266.889 343.977 114.780 1.00 79.69  ? 99  GLN B CD  1 
ATOM 2421 O OE1 . GLN B 1 99  ? 266.133 343.357 115.528 1.00 79.69  ? 99  GLN B OE1 1 
ATOM 2422 N NE2 . GLN B 1 99  ? 266.460 344.624 113.700 1.00 79.69  ? 99  GLN B NE2 1 
ATOM 2423 N N   . GLU B 1 100 ? 271.953 340.860 114.155 1.00 75.09  ? 100 GLU B N   1 
ATOM 2424 C CA  . GLU B 1 100 ? 272.400 339.475 114.185 1.00 75.09  ? 100 GLU B CA  1 
ATOM 2425 C C   . GLU B 1 100 ? 273.822 339.433 113.643 1.00 75.09  ? 100 GLU B C   1 
ATOM 2426 O O   . GLU B 1 100 ? 274.096 339.975 112.569 1.00 75.09  ? 100 GLU B O   1 
ATOM 2427 C CB  . GLU B 1 100 ? 271.458 338.586 113.359 1.00 75.09  ? 100 GLU B CB  1 
ATOM 2428 C CG  . GLU B 1 100 ? 271.583 337.070 113.567 1.00 75.09  ? 100 GLU B CG  1 
ATOM 2429 C CD  . GLU B 1 100 ? 272.772 336.430 112.870 1.00 75.09  ? 100 GLU B CD  1 
ATOM 2430 O OE1 . GLU B 1 100 ? 273.603 335.814 113.568 1.00 75.09  ? 100 GLU B OE1 1 
ATOM 2431 O OE2 . GLU B 1 100 ? 272.873 336.542 111.631 1.00 75.09  ? 100 GLU B OE2 1 
ATOM 2432 N N   . PHE B 1 101 ? 274.721 338.801 114.405 1.00 76.52  ? 101 PHE B N   1 
ATOM 2433 C CA  . PHE B 1 101 ? 276.132 338.707 114.047 1.00 76.52  ? 101 PHE B CA  1 
ATOM 2434 C C   . PHE B 1 101 ? 276.734 337.380 114.497 1.00 76.52  ? 101 PHE B C   1 
ATOM 2435 O O   . PHE B 1 101 ? 277.964 337.241 114.503 1.00 76.52  ? 101 PHE B O   1 
ATOM 2436 C CB  . PHE B 1 101 ? 276.903 339.887 114.667 1.00 76.52  ? 101 PHE B CB  1 
ATOM 2437 C CG  . PHE B 1 101 ? 278.148 340.268 113.923 1.00 76.52  ? 101 PHE B CG  1 
ATOM 2438 C CD1 . PHE B 1 101 ? 278.078 340.741 112.622 1.00 76.52  ? 101 PHE B CD1 1 
ATOM 2439 C CD2 . PHE B 1 101 ? 279.389 340.172 114.534 1.00 76.52  ? 101 PHE B CD2 1 
ATOM 2440 C CE1 . PHE B 1 101 ? 279.226 341.095 111.935 1.00 76.52  ? 101 PHE B CE1 1 
ATOM 2441 C CE2 . PHE B 1 101 ? 280.542 340.530 113.857 1.00 76.52  ? 101 PHE B CE2 1 
ATOM 2442 C CZ  . PHE B 1 101 ? 280.460 340.991 112.555 1.00 76.52  ? 101 PHE B CZ  1 
ATOM 2443 N N   . LYS B 1 102 ? 275.905 336.400 114.845 1.00 67.48  ? 102 LYS B N   1 
ATOM 2444 C CA  . LYS B 1 102 ? 276.341 335.278 115.658 1.00 67.48  ? 102 LYS B CA  1 
ATOM 2445 C C   . LYS B 1 102 ? 277.087 334.230 114.831 1.00 67.48  ? 102 LYS B C   1 
ATOM 2446 O O   . LYS B 1 102 ? 276.764 334.000 113.663 1.00 67.48  ? 102 LYS B O   1 
ATOM 2447 C CB  . LYS B 1 102 ? 275.136 334.637 116.343 1.00 67.48  ? 102 LYS B CB  1 
ATOM 2448 C CG  . LYS B 1 102 ? 274.343 335.589 117.228 1.00 67.48  ? 102 LYS B CG  1 
ATOM 2449 C CD  . LYS B 1 102 ? 275.252 336.351 118.186 1.00 67.48  ? 102 LYS B CD  1 
ATOM 2450 C CE  . LYS B 1 102 ? 274.668 337.702 118.556 1.00 67.48  ? 102 LYS B CE  1 
ATOM 2451 N NZ  . LYS B 1 102 ? 274.842 338.699 117.471 1.00 67.48  ? 102 LYS B NZ  1 
ATOM 2452 N N   . PRO B 1 103 ? 278.088 333.576 115.421 1.00 65.53  ? 103 PRO B N   1 
ATOM 2453 C CA  . PRO B 1 103 ? 278.767 332.480 114.727 1.00 65.53  ? 103 PRO B CA  1 
ATOM 2454 C C   . PRO B 1 103 ? 277.984 331.181 114.840 1.00 65.53  ? 103 PRO B C   1 
ATOM 2455 O O   . PRO B 1 103 ? 276.868 331.132 115.362 1.00 65.53  ? 103 PRO B O   1 
ATOM 2456 C CB  . PRO B 1 103 ? 280.109 332.383 115.456 1.00 65.53  ? 103 PRO B CB  1 
ATOM 2457 C CG  . PRO B 1 103 ? 279.778 332.790 116.849 1.00 65.53  ? 103 PRO B CG  1 
ATOM 2458 C CD  . PRO B 1 103 ? 278.708 333.853 116.731 1.00 65.53  ? 103 PRO B CD  1 
ATOM 2459 N N   . VAL B 1 104 ? 278.600 330.107 114.344 1.00 68.55  ? 104 VAL B N   1 
ATOM 2460 C CA  . VAL B 1 104 ? 277.957 328.798 114.321 1.00 68.55  ? 104 VAL B CA  1 
ATOM 2461 C C   . VAL B 1 104 ? 278.222 328.108 115.658 1.00 68.55  ? 104 VAL B C   1 
ATOM 2462 O O   . VAL B 1 104 ? 279.228 327.404 115.822 1.00 68.55  ? 104 VAL B O   1 
ATOM 2463 C CB  . VAL B 1 104 ? 278.444 327.961 113.116 1.00 68.55  ? 104 VAL B CB  1 
ATOM 2464 C CG1 . VAL B 1 104 ? 277.819 326.558 113.087 1.00 68.55  ? 104 VAL B CG1 1 
ATOM 2465 C CG2 . VAL B 1 104 ? 278.155 328.691 111.811 1.00 68.55  ? 104 VAL B CG2 1 
ATOM 2466 N N   . GLY B 1 105 ? 277.363 328.398 116.638 1.00 73.48  ? 105 GLY B N   1 
ATOM 2467 C CA  . GLY B 1 105 ? 277.158 327.609 117.849 1.00 73.48  ? 105 GLY B CA  1 
ATOM 2468 C C   . GLY B 1 105 ? 278.381 327.366 118.696 1.00 73.48  ? 105 GLY B C   1 
ATOM 2469 O O   . GLY B 1 105 ? 279.013 328.299 119.206 1.00 73.48  ? 105 GLY B O   1 
ATOM 2470 N N   . ASP B 1 106 ? 278.710 326.085 118.864 1.00 67.46  ? 106 ASP B N   1 
ATOM 2471 C CA  . ASP B 1 106 ? 279.948 325.694 119.522 1.00 67.46  ? 106 ASP B CA  1 
ATOM 2472 C C   . ASP B 1 106 ? 281.116 326.100 118.642 1.00 67.46  ? 106 ASP B C   1 
ATOM 2473 O O   . ASP B 1 106 ? 281.439 325.416 117.666 1.00 67.46  ? 106 ASP B O   1 
ATOM 2474 C CB  . ASP B 1 106 ? 279.972 324.190 119.801 1.00 67.46  ? 106 ASP B CB  1 
ATOM 2475 C CG  . ASP B 1 106 ? 280.861 323.829 120.972 1.00 67.46  ? 106 ASP B CG  1 
ATOM 2476 O OD1 . ASP B 1 106 ? 281.300 322.665 121.069 1.00 67.46  ? 106 ASP B OD1 1 
ATOM 2477 O OD2 . ASP B 1 106 ? 281.158 324.722 121.777 1.00 67.46  ? 106 ASP B OD2 1 
ATOM 2478 N N   . ALA B 1 107 ? 281.741 327.224 118.987 1.00 64.81  ? 107 ALA B N   1 
ATOM 2479 C CA  . ALA B 1 107 ? 282.807 327.793 118.179 1.00 64.81  ? 107 ALA B CA  1 
ATOM 2480 C C   . ALA B 1 107 ? 284.053 326.934 118.306 1.00 64.81  ? 107 ALA B C   1 
ATOM 2481 O O   . ALA B 1 107 ? 284.586 326.444 117.306 1.00 64.81  ? 107 ALA B O   1 
ATOM 2482 C CB  . ALA B 1 107 ? 283.088 329.233 118.606 1.00 64.81  ? 107 ALA B CB  1 
ATOM 2483 N N   . GLY B 1 108 ? 284.513 326.739 119.536 1.00 59.03  ? 108 GLY B N   1 
ATOM 2484 C CA  . GLY B 1 108 ? 285.666 325.900 119.775 1.00 59.03  ? 108 GLY B CA  1 
ATOM 2485 C C   . GLY B 1 108 ? 285.564 325.055 121.026 1.00 59.03  ? 108 GLY B C   1 
ATOM 2486 O O   . GLY B 1 108 ? 286.584 324.789 121.667 1.00 59.03  ? 108 GLY B O   1 
ATOM 2487 N N   . GLY B 1 109 ? 284.364 324.608 121.387 1.00 54.52  ? 109 GLY B N   1 
ATOM 2488 C CA  . GLY B 1 109 ? 284.256 323.907 122.646 1.00 54.52  ? 109 GLY B CA  1 
ATOM 2489 C C   . GLY B 1 109 ? 283.845 324.788 123.803 1.00 54.52  ? 109 GLY B C   1 
ATOM 2490 O O   . GLY B 1 109 ? 284.647 324.996 124.717 1.00 54.52  ? 109 GLY B O   1 
ATOM 2491 N N   . ARG B 1 110 ? 282.636 325.372 123.734 1.00 47.20  ? 110 ARG B N   1 
ATOM 2492 C CA  . ARG B 1 110 ? 282.080 326.177 124.828 1.00 47.20  ? 110 ARG B CA  1 
ATOM 2493 C C   . ARG B 1 110 ? 282.060 325.417 126.155 1.00 47.20  ? 110 ARG B C   1 
ATOM 2494 O O   . ARG B 1 110 ? 282.148 326.016 127.231 1.00 47.20  ? 110 ARG B O   1 
ATOM 2495 C CB  . ARG B 1 110 ? 280.664 326.656 124.467 1.00 47.20  ? 110 ARG B CB  1 
ATOM 2496 C CG  . ARG B 1 110 ? 279.564 325.570 124.452 1.00 47.20  ? 110 ARG B CG  1 
ATOM 2497 C CD  . ARG B 1 110 ? 278.275 326.039 123.813 1.00 47.20  ? 110 ARG B CD  1 
ATOM 2498 N NE  . ARG B 1 110 ? 277.409 326.701 124.779 1.00 47.20  ? 110 ARG B NE  1 
ATOM 2499 C CZ  . ARG B 1 110 ? 276.510 327.627 124.465 1.00 47.20  ? 110 ARG B CZ  1 
ATOM 2500 N NH1 . ARG B 1 110 ? 275.763 328.177 125.414 1.00 47.20  ? 110 ARG B NH1 1 
ATOM 2501 N NH2 . ARG B 1 110 ? 276.359 328.002 123.203 1.00 47.20  ? 110 ARG B NH2 1 
ATOM 2502 N N   . MET B 1 111 ? 281.949 324.095 126.095 1.00 32.78  ? 111 MET B N   1 
ATOM 2503 C CA  . MET B 1 111 ? 282.113 323.259 127.263 1.00 32.78  ? 111 MET B CA  1 
ATOM 2504 C C   . MET B 1 111 ? 283.386 322.439 127.115 1.00 32.78  ? 111 MET B C   1 
ATOM 2505 O O   . MET B 1 111 ? 283.715 321.969 126.023 1.00 32.78  ? 111 MET B O   1 
ATOM 2506 C CB  . MET B 1 111 ? 280.879 322.378 127.432 1.00 32.78  ? 111 MET B CB  1 
ATOM 2507 C CG  . MET B 1 111 ? 280.486 321.615 126.192 1.00 32.78  ? 111 MET B CG  1 
ATOM 2508 S SD  . MET B 1 111 ? 278.736 321.246 126.188 1.00 32.78  ? 111 MET B SD  1 
ATOM 2509 C CE  . MET B 1 111 ? 278.592 320.449 127.772 1.00 32.78  ? 111 MET B CE  1 
ATOM 2510 N N   . ASP B 1 112 ? 284.132 322.316 128.207 1.00 28.25  ? 112 ASP B N   1 
ATOM 2511 C CA  . ASP B 1 112 ? 285.410 321.619 128.202 1.00 28.25  ? 112 ASP B CA  1 
ATOM 2512 C C   . ASP B 1 112 ? 285.191 320.229 128.771 1.00 28.25  ? 112 ASP B C   1 
ATOM 2513 O O   . ASP B 1 112 ? 285.116 320.055 129.991 1.00 28.25  ? 112 ASP B O   1 
ATOM 2514 C CB  . ASP B 1 112 ? 286.459 322.379 129.006 1.00 28.25  ? 112 ASP B CB  1 
ATOM 2515 C CG  . ASP B 1 112 ? 287.800 321.667 129.033 1.00 28.25  ? 112 ASP B CG  1 
ATOM 2516 O OD1 . ASP B 1 112 ? 288.181 321.081 127.999 1.00 28.25  ? 112 ASP B OD1 1 
ATOM 2517 O OD2 . ASP B 1 112 ? 288.476 321.688 130.084 1.00 28.25  ? 112 ASP B OD2 1 
ATOM 2518 N N   . ILE B 1 113 ? 285.094 319.241 127.891 1.00 20.44  ? 113 ILE B N   1 
ATOM 2519 C CA  . ILE B 1 113 ? 284.824 317.870 128.287 1.00 20.44  ? 113 ILE B CA  1 
ATOM 2520 C C   . ILE B 1 113 ? 286.102 317.068 128.118 1.00 20.44  ? 113 ILE B C   1 
ATOM 2521 O O   . ILE B 1 113 ? 286.843 317.249 127.147 1.00 20.44  ? 113 ILE B O   1 
ATOM 2522 C CB  . ILE B 1 113 ? 283.661 317.273 127.474 1.00 20.44  ? 113 ILE B CB  1 
ATOM 2523 C CG1 . ILE B 1 113 ? 282.423 318.121 127.682 1.00 20.44  ? 113 ILE B CG1 1 
ATOM 2524 C CG2 . ILE B 1 113 ? 283.321 315.884 127.937 1.00 20.44  ? 113 ILE B CG2 1 
ATOM 2525 C CD1 . ILE B 1 113 ? 281.309 317.735 126.814 1.00 20.44  ? 113 ILE B CD1 1 
ATOM 2526 N N   . ASP B 1 114 ? 286.376 316.215 129.093 1.00 16.64  ? 114 ASP B N   1 
ATOM 2527 C CA  . ASP B 1 114 ? 287.547 315.371 129.115 1.00 16.64  ? 114 ASP B CA  1 
ATOM 2528 C C   . ASP B 1 114 ? 287.113 313.935 128.886 1.00 16.64  ? 114 ASP B C   1 
ATOM 2529 O O   . ASP B 1 114 ? 286.346 313.400 129.698 1.00 16.64  ? 114 ASP B O   1 
ATOM 2530 C CB  . ASP B 1 114 ? 288.237 315.523 130.461 1.00 16.64  ? 114 ASP B CB  1 
ATOM 2531 C CG  . ASP B 1 114 ? 289.616 314.952 130.479 1.00 16.64  ? 114 ASP B CG  1 
ATOM 2532 O OD1 . ASP B 1 114 ? 290.579 315.725 130.324 1.00 16.64  ? 114 ASP B OD1 1 
ATOM 2533 O OD2 . ASP B 1 114 ? 289.732 313.733 130.673 1.00 16.64  ? 114 ASP B OD2 1 
ATOM 2534 N N   . PRO B 1 115 ? 287.550 313.275 127.810 1.00 17.70  ? 115 PRO B N   1 
ATOM 2535 C CA  . PRO B 1 115 ? 286.972 311.971 127.459 1.00 17.70  ? 115 PRO B CA  1 
ATOM 2536 C C   . PRO B 1 115 ? 287.350 310.835 128.382 1.00 17.70  ? 115 PRO B C   1 
ATOM 2537 O O   . PRO B 1 115 ? 286.767 309.753 128.248 1.00 17.70  ? 115 PRO B O   1 
ATOM 2538 C CB  . PRO B 1 115 ? 287.503 311.719 126.048 1.00 17.70  ? 115 PRO B CB  1 
ATOM 2539 C CG  . PRO B 1 115 ? 288.614 312.640 125.871 1.00 17.70  ? 115 PRO B CG  1 
ATOM 2540 C CD  . PRO B 1 115 ? 288.361 313.824 126.717 1.00 17.70  ? 115 PRO B CD  1 
ATOM 2541 N N   . TYR B 1 116 ? 288.286 311.027 129.308 1.00 12.80  ? 116 TYR B N   1 
ATOM 2542 C CA  . TYR B 1 116 ? 288.673 309.983 130.240 1.00 12.80  ? 116 TYR B CA  1 
ATOM 2543 C C   . TYR B 1 116 ? 288.361 310.328 131.685 1.00 12.80  ? 116 TYR B C   1 
ATOM 2544 O O   . TYR B 1 116 ? 288.615 309.501 132.561 1.00 12.80  ? 116 TYR B O   1 
ATOM 2545 C CB  . TYR B 1 116 ? 290.166 309.679 130.110 1.00 12.80  ? 116 TYR B CB  1 
ATOM 2546 C CG  . TYR B 1 116 ? 290.685 309.654 128.701 1.00 12.80  ? 116 TYR B CG  1 
ATOM 2547 C CD1 . TYR B 1 116 ? 290.541 308.535 127.914 1.00 12.80  ? 116 TYR B CD1 1 
ATOM 2548 C CD2 . TYR B 1 116 ? 291.326 310.743 128.165 1.00 12.80  ? 116 TYR B CD2 1 
ATOM 2549 C CE1 . TYR B 1 116 ? 291.007 308.511 126.633 1.00 12.80  ? 116 TYR B CE1 1 
ATOM 2550 C CE2 . TYR B 1 116 ? 291.804 310.723 126.893 1.00 12.80  ? 116 TYR B CE2 1 
ATOM 2551 C CZ  . TYR B 1 116 ? 291.641 309.610 126.130 1.00 12.80  ? 116 TYR B CZ  1 
ATOM 2552 O OH  . TYR B 1 116 ? 292.115 309.612 124.851 1.00 12.80  ? 116 TYR B OH  1 
ATOM 2553 N N   . LYS B 1 117 ? 287.775 311.495 131.952 1.00 18.52  ? 117 LYS B N   1 
ATOM 2554 C CA  . LYS B 1 117 ? 287.678 312.005 133.315 1.00 18.52  ? 117 LYS B CA  1 
ATOM 2555 C C   . LYS B 1 117 ? 286.676 311.236 134.150 1.00 18.52  ? 117 LYS B C   1 
ATOM 2556 O O   . LYS B 1 117 ? 286.827 311.150 135.371 1.00 18.52  ? 117 LYS B O   1 
ATOM 2557 C CB  . LYS B 1 117 ? 287.305 313.477 133.279 1.00 18.52  ? 117 LYS B CB  1 
ATOM 2558 C CG  . LYS B 1 117 ? 287.550 314.250 134.536 1.00 18.52  ? 117 LYS B CG  1 
ATOM 2559 C CD  . LYS B 1 117 ? 287.550 315.727 134.227 1.00 18.52  ? 117 LYS B CD  1 
ATOM 2560 C CE  . LYS B 1 117 ? 286.686 316.499 135.190 1.00 18.52  ? 117 LYS B CE  1 
ATOM 2561 N NZ  . LYS B 1 117 ? 287.148 316.305 136.583 1.00 18.52  ? 117 LYS B NZ  1 
ATOM 2562 N N   . GLU B 1 118 ? 285.647 310.682 133.520 1.00 20.08  ? 118 GLU B N   1 
ATOM 2563 C CA  . GLU B 1 118 ? 284.713 309.824 134.232 1.00 20.08  ? 118 GLU B CA  1 
ATOM 2564 C C   . GLU B 1 118 ? 285.306 308.464 134.552 1.00 20.08  ? 118 GLU B C   1 
ATOM 2565 O O   . GLU B 1 118 ? 284.823 307.788 135.462 1.00 20.08  ? 118 GLU B O   1 
ATOM 2566 C CB  . GLU B 1 118 ? 283.442 309.671 133.409 1.00 20.08  ? 118 GLU B CB  1 
ATOM 2567 C CG  . GLU B 1 118 ? 283.740 309.397 131.960 1.00 20.08  ? 118 GLU B CG  1 
ATOM 2568 C CD  . GLU B 1 118 ? 282.517 309.072 131.142 1.00 20.08  ? 118 GLU B CD  1 
ATOM 2569 O OE1 . GLU B 1 118 ? 281.439 308.873 131.734 1.00 20.08  ? 118 GLU B OE1 1 
ATOM 2570 O OE2 . GLU B 1 118 ? 282.632 309.050 129.902 1.00 20.08  ? 118 GLU B OE2 1 
ATOM 2571 N N   . PHE B 1 119 ? 286.354 308.061 133.836 1.00 14.52  ? 119 PHE B N   1 
ATOM 2572 C CA  . PHE B 1 119 ? 286.947 306.740 133.951 1.00 14.52  ? 119 PHE B CA  1 
ATOM 2573 C C   . PHE B 1 119 ? 288.179 306.724 134.828 1.00 14.52  ? 119 PHE B C   1 
ATOM 2574 O O   . PHE B 1 119 ? 288.989 305.805 134.719 1.00 14.52  ? 119 PHE B O   1 
ATOM 2575 C CB  . PHE B 1 119 ? 287.310 306.219 132.571 1.00 14.52  ? 119 PHE B CB  1 
ATOM 2576 C CG  . PHE B 1 119 ? 286.145 306.044 131.681 1.00 14.52  ? 119 PHE B CG  1 
ATOM 2577 C CD1 . PHE B 1 119 ? 285.201 305.085 131.952 1.00 14.52  ? 119 PHE B CD1 1 
ATOM 2578 C CD2 . PHE B 1 119 ? 285.985 306.843 130.576 1.00 14.52  ? 119 PHE B CD2 1 
ATOM 2579 C CE1 . PHE B 1 119 ? 284.133 304.920 131.130 1.00 14.52  ? 119 PHE B CE1 1 
ATOM 2580 C CE2 . PHE B 1 119 ? 284.906 306.687 129.761 1.00 14.52  ? 119 PHE B CE2 1 
ATOM 2581 C CZ  . PHE B 1 119 ? 283.984 305.717 130.035 1.00 14.52  ? 119 PHE B CZ  1 
ATOM 2582 N N   . GLY B 1 120 ? 288.347 307.712 135.675 1.00 28.56  ? 120 GLY B N   1 
ATOM 2583 C CA  . GLY B 1 120 ? 289.556 307.815 136.465 1.00 28.56  ? 120 GLY B CA  1 
ATOM 2584 C C   . GLY B 1 120 ? 290.633 308.677 135.863 1.00 28.56  ? 120 GLY B C   1 
ATOM 2585 O O   . GLY B 1 120 ? 291.124 309.594 136.511 1.00 28.56  ? 120 GLY B O   1 
ATOM 2586 N N   . ALA B 1 121 ? 290.991 308.427 134.615 1.00 8.68   ? 121 ALA B N   1 
ATOM 2587 C CA  . ALA B 1 121 ? 292.154 309.061 134.019 1.00 8.68   ? 121 ALA B CA  1 
ATOM 2588 C C   . ALA B 1 121 ? 291.814 310.473 133.582 1.00 8.68   ? 121 ALA B C   1 
ATOM 2589 O O   . ALA B 1 121 ? 290.739 310.991 133.871 1.00 8.68   ? 121 ALA B O   1 
ATOM 2590 C CB  . ALA B 1 121 ? 292.664 308.237 132.847 1.00 8.68   ? 121 ALA B CB  1 
ATOM 2591 N N   . THR B 1 122 ? 292.754 311.125 132.904 1.00 8.22   ? 122 THR B N   1 
ATOM 2592 C CA  . THR B 1 122 ? 292.552 312.394 132.225 1.00 8.22   ? 122 THR B CA  1 
ATOM 2593 C C   . THR B 1 122 ? 293.332 312.352 130.926 1.00 8.22   ? 122 THR B C   1 
ATOM 2594 O O   . THR B 1 122 ? 293.951 311.348 130.589 1.00 8.22   ? 122 THR B O   1 
ATOM 2595 C CB  . THR B 1 122 ? 293.000 313.597 133.061 1.00 8.22   ? 122 THR B CB  1 
ATOM 2596 O OG1 . THR B 1 122 ? 294.306 313.362 133.585 1.00 8.22   ? 122 THR B OG1 1 
ATOM 2597 C CG2 . THR B 1 122 ? 292.042 313.924 134.178 1.00 8.22   ? 122 THR B CG2 1 
ATOM 2598 N N   . VAL B 1 123 ? 293.292 313.449 130.180 1.00 8.93   ? 123 VAL B N   1 
ATOM 2599 C CA  . VAL B 1 123 ? 294.088 313.531 128.967 1.00 8.93   ? 123 VAL B CA  1 
ATOM 2600 C C   . VAL B 1 123 ? 295.532 313.822 129.319 1.00 8.93   ? 123 VAL B C   1 
ATOM 2601 O O   . VAL B 1 123 ? 296.447 313.423 128.596 1.00 8.93   ? 123 VAL B O   1 
ATOM 2602 C CB  . VAL B 1 123 ? 293.488 314.590 128.029 1.00 8.93   ? 123 VAL B CB  1 
ATOM 2603 C CG1 . VAL B 1 123 ? 294.205 314.646 126.693 1.00 8.93   ? 123 VAL B CG1 1 
ATOM 2604 C CG2 . VAL B 1 123 ? 292.033 314.287 127.801 1.00 8.93   ? 123 VAL B CG2 1 
ATOM 2605 N N   . GLU B 1 124 ? 295.769 314.471 130.455 1.00 12.39  ? 124 GLU B N   1 
ATOM 2606 C CA  . GLU B 1 124 ? 297.134 314.754 130.878 1.00 12.39  ? 124 GLU B CA  1 
ATOM 2607 C C   . GLU B 1 124 ? 297.849 313.493 131.332 1.00 12.39  ? 124 GLU B C   1 
ATOM 2608 O O   . GLU B 1 124 ? 299.076 313.418 131.251 1.00 12.39  ? 124 GLU B O   1 
ATOM 2609 C CB  . GLU B 1 124 ? 297.132 315.798 131.993 1.00 12.39  ? 124 GLU B CB  1 
ATOM 2610 C CG  . GLU B 1 124 ? 296.970 317.235 131.508 1.00 12.39  ? 124 GLU B CG  1 
ATOM 2611 C CD  . GLU B 1 124 ? 295.542 317.581 131.117 1.00 12.39  ? 124 GLU B CD  1 
ATOM 2612 O OE1 . GLU B 1 124 ? 294.614 317.284 131.898 1.00 12.39  ? 124 GLU B OE1 1 
ATOM 2613 O OE2 . GLU B 1 124 ? 295.348 318.158 130.027 1.00 12.39  ? 124 GLU B OE2 1 
ATOM 2614 N N   . LEU B 1 125 ? 297.101 312.493 131.793 1.00 13.69  ? 125 LEU B N   1 
ATOM 2615 C CA  . LEU B 1 125 ? 297.689 311.207 132.141 1.00 13.69  ? 125 LEU B CA  1 
ATOM 2616 C C   . LEU B 1 125 ? 298.047 310.386 130.912 1.00 13.69  ? 125 LEU B C   1 
ATOM 2617 O O   . LEU B 1 125 ? 298.983 309.590 130.960 1.00 13.69  ? 125 LEU B O   1 
ATOM 2618 C CB  . LEU B 1 125 ? 296.725 310.427 133.021 1.00 13.69  ? 125 LEU B CB  1 
ATOM 2619 C CG  . LEU B 1 125 ? 297.262 309.268 133.838 1.00 13.69  ? 125 LEU B CG  1 
ATOM 2620 C CD1 . LEU B 1 125 ? 298.148 309.783 134.934 1.00 13.69  ? 125 LEU B CD1 1 
ATOM 2621 C CD2 . LEU B 1 125 ? 296.113 308.498 134.414 1.00 13.69  ? 125 LEU B CD2 1 
ATOM 2622 N N   . LEU B 1 126 ? 297.320 310.547 129.816 1.00 11.49  ? 126 LEU B N   1 
ATOM 2623 C CA  . LEU B 1 126 ? 297.569 309.771 128.615 1.00 11.49  ? 126 LEU B CA  1 
ATOM 2624 C C   . LEU B 1 126 ? 298.337 310.529 127.560 1.00 11.49  ? 126 LEU B C   1 
ATOM 2625 O O   . LEU B 1 126 ? 298.545 309.995 126.471 1.00 11.49  ? 126 LEU B O   1 
ATOM 2626 C CB  . LEU B 1 126 ? 296.263 309.276 127.989 1.00 11.49  ? 126 LEU B CB  1 
ATOM 2627 C CG  . LEU B 1 126 ? 295.628 307.994 128.514 1.00 11.49  ? 126 LEU B CG  1 
ATOM 2628 C CD1 . LEU B 1 126 ? 294.791 308.227 129.731 1.00 11.49  ? 126 LEU B CD1 1 
ATOM 2629 C CD2 . LEU B 1 126 ? 294.845 307.348 127.434 1.00 11.49  ? 126 LEU B CD2 1 
ATOM 2630 N N   . SER B 1 127 ? 298.745 311.754 127.831 1.00 8.79   ? 127 SER B N   1 
ATOM 2631 C CA  . SER B 1 127 ? 299.498 312.519 126.853 1.00 8.79   ? 127 SER B CA  1 
ATOM 2632 C C   . SER B 1 127 ? 300.973 312.205 126.894 1.00 8.79   ? 127 SER B C   1 
ATOM 2633 O O   . SER B 1 127 ? 301.728 312.747 126.087 1.00 8.79   ? 127 SER B O   1 
ATOM 2634 C CB  . SER B 1 127 ? 299.293 314.011 127.078 1.00 8.79   ? 127 SER B CB  1 
ATOM 2635 O OG  . SER B 1 127 ? 299.325 314.318 128.458 1.00 8.79   ? 127 SER B OG  1 
ATOM 2636 N N   . PHE B 1 128 ? 301.391 311.349 127.821 1.00 11.20  ? 128 PHE B N   1 
ATOM 2637 C CA  . PHE B 1 128 ? 302.780 310.956 127.982 1.00 11.20  ? 128 PHE B CA  1 
ATOM 2638 C C   . PHE B 1 128 ? 303.145 309.760 127.135 1.00 11.20  ? 128 PHE B C   1 
ATOM 2639 O O   . PHE B 1 128 ? 304.318 309.596 126.797 1.00 11.20  ? 128 PHE B O   1 
ATOM 2640 C CB  . PHE B 1 128 ? 303.064 310.640 129.446 1.00 11.20  ? 128 PHE B CB  1 
ATOM 2641 C CG  . PHE B 1 128 ? 303.105 311.849 130.312 1.00 11.20  ? 128 PHE B CG  1 
ATOM 2642 C CD1 . PHE B 1 128 ? 303.806 312.971 129.910 1.00 11.20  ? 128 PHE B CD1 1 
ATOM 2643 C CD2 . PHE B 1 128 ? 302.430 311.877 131.513 1.00 11.20  ? 128 PHE B CD2 1 
ATOM 2644 C CE1 . PHE B 1 128 ? 303.838 314.085 130.687 1.00 11.20  ? 128 PHE B CE1 1 
ATOM 2645 C CE2 . PHE B 1 128 ? 302.459 312.994 132.294 1.00 11.20  ? 128 PHE B CE2 1 
ATOM 2646 C CZ  . PHE B 1 128 ? 303.166 314.098 131.881 1.00 11.20  ? 128 PHE B CZ  1 
ATOM 2647 N N   . LEU B 1 129 ? 302.166 308.926 126.814 1.00 11.20  ? 129 LEU B N   1 
ATOM 2648 C CA  . LEU B 1 129 ? 302.378 307.766 125.964 1.00 11.20  ? 129 LEU B CA  1 
ATOM 2649 C C   . LEU B 1 129 ? 302.790 308.231 124.574 1.00 11.20  ? 129 LEU B C   1 
ATOM 2650 O O   . LEU B 1 129 ? 302.235 309.205 124.062 1.00 11.20  ? 129 LEU B O   1 
ATOM 2651 C CB  . LEU B 1 129 ? 301.098 306.941 125.869 1.00 11.20  ? 129 LEU B CB  1 
ATOM 2652 C CG  . LEU B 1 129 ? 300.750 305.812 126.837 1.00 11.20  ? 129 LEU B CG  1 
ATOM 2653 C CD1 . LEU B 1 129 ? 301.064 306.162 128.231 1.00 11.20  ? 129 LEU B CD1 1 
ATOM 2654 C CD2 . LEU B 1 129 ? 299.294 305.530 126.764 1.00 11.20  ? 129 LEU B CD2 1 
ATOM 2655 N N   . PRO B 1 130 ? 303.773 307.593 123.954 1.00 9.93   ? 130 PRO B N   1 
ATOM 2656 C CA  . PRO B 1 130 ? 304.257 308.065 122.659 1.00 9.93   ? 130 PRO B CA  1 
ATOM 2657 C C   . PRO B 1 130 ? 303.249 307.772 121.567 1.00 9.93   ? 130 PRO B C   1 
ATOM 2658 O O   . PRO B 1 130 ? 302.252 307.082 121.764 1.00 9.93   ? 130 PRO B O   1 
ATOM 2659 C CB  . PRO B 1 130 ? 305.547 307.278 122.451 1.00 9.93   ? 130 PRO B CB  1 
ATOM 2660 C CG  . PRO B 1 130 ? 305.859 306.687 123.763 1.00 9.93   ? 130 PRO B CG  1 
ATOM 2661 C CD  . PRO B 1 130 ? 304.579 306.475 124.449 1.00 9.93   ? 130 PRO B CD  1 
ATOM 2662 N N   . SER B 1 131 ? 303.525 308.316 120.389 1.00 19.67  ? 131 SER B N   1 
ATOM 2663 C CA  . SER B 1 131 ? 302.591 308.189 119.282 1.00 19.67  ? 131 SER B CA  1 
ATOM 2664 C C   . SER B 1 131 ? 302.537 306.779 118.720 1.00 19.67  ? 131 SER B C   1 
ATOM 2665 O O   . SER B 1 131 ? 301.541 306.417 118.093 1.00 19.67  ? 131 SER B O   1 
ATOM 2666 C CB  . SER B 1 131 ? 302.970 309.172 118.187 1.00 19.67  ? 131 SER B CB  1 
ATOM 2667 O OG  . SER B 1 131 ? 304.374 309.195 118.021 1.00 19.67  ? 131 SER B OG  1 
ATOM 2668 N N   . ASP B 1 132 ? 303.573 305.971 118.937 1.00 19.05  ? 132 ASP B N   1 
ATOM 2669 C CA  . ASP B 1 132 ? 303.613 304.605 118.438 1.00 19.05  ? 132 ASP B CA  1 
ATOM 2670 C C   . ASP B 1 132 ? 303.523 303.578 119.554 1.00 19.05  ? 132 ASP B C   1 
ATOM 2671 O O   . ASP B 1 132 ? 303.909 302.427 119.364 1.00 19.05  ? 132 ASP B O   1 
ATOM 2672 C CB  . ASP B 1 132 ? 304.873 304.381 117.608 1.00 19.05  ? 132 ASP B CB  1 
ATOM 2673 C CG  . ASP B 1 132 ? 306.094 305.002 118.231 1.00 19.05  ? 132 ASP B CG  1 
ATOM 2674 O OD1 . ASP B 1 132 ? 306.007 305.476 119.377 1.00 19.05  ? 132 ASP B OD1 1 
ATOM 2675 O OD2 . ASP B 1 132 ? 307.147 305.030 117.565 1.00 19.05  ? 132 ASP B OD2 1 
ATOM 2676 N N   . PHE B 1 133 ? 303.030 303.975 120.718 1.00 14.85  ? 133 PHE B N   1 
ATOM 2677 C CA  . PHE B 1 133 ? 302.723 303.006 121.752 1.00 14.85  ? 133 PHE B CA  1 
ATOM 2678 C C   . PHE B 1 133 ? 301.487 302.207 121.398 1.00 14.85  ? 133 PHE B C   1 
ATOM 2679 O O   . PHE B 1 133 ? 301.353 301.052 121.810 1.00 14.85  ? 133 PHE B O   1 
ATOM 2680 C CB  . PHE B 1 133 ? 302.523 303.726 123.070 1.00 14.85  ? 133 PHE B CB  1 
ATOM 2681 C CG  . PHE B 1 133 ? 302.046 302.862 124.168 1.00 14.85  ? 133 PHE B CG  1 
ATOM 2682 C CD1 . PHE B 1 133 ? 302.899 301.995 124.784 1.00 14.85  ? 133 PHE B CD1 1 
ATOM 2683 C CD2 . PHE B 1 133 ? 300.751 302.937 124.605 1.00 14.85  ? 133 PHE B CD2 1 
ATOM 2684 C CE1 . PHE B 1 133 ? 302.464 301.205 125.807 1.00 14.85  ? 133 PHE B CE1 1 
ATOM 2685 C CE2 . PHE B 1 133 ? 300.317 302.157 125.624 1.00 14.85  ? 133 PHE B CE2 1 
ATOM 2686 C CZ  . PHE B 1 133 ? 301.169 301.290 126.225 1.00 14.85  ? 133 PHE B CZ  1 
ATOM 2687 N N   . PHE B 1 134 ? 300.600 302.787 120.652 1.00 12.59  ? 134 PHE B N   1 
ATOM 2688 C CA  . PHE B 1 134 ? 299.300 302.223 120.336 1.00 12.59  ? 134 PHE B CA  1 
ATOM 2689 C C   . PHE B 1 134 ? 299.390 301.414 119.061 1.00 12.59  ? 134 PHE B C   1 
ATOM 2690 O O   . PHE B 1 134 ? 300.028 301.858 118.102 1.00 12.59  ? 134 PHE B O   1 
ATOM 2691 C CB  . PHE B 1 134 ? 298.269 303.320 120.166 1.00 12.59  ? 134 PHE B CB  1 
ATOM 2692 C CG  . PHE B 1 134 ? 298.268 304.298 121.270 1.00 12.59  ? 134 PHE B CG  1 
ATOM 2693 C CD1 . PHE B 1 134 ? 297.755 303.954 122.495 1.00 12.59  ? 134 PHE B CD1 1 
ATOM 2694 C CD2 . PHE B 1 134 ? 298.816 305.544 121.099 1.00 12.59  ? 134 PHE B CD2 1 
ATOM 2695 C CE1 . PHE B 1 134 ? 297.767 304.836 123.520 1.00 12.59  ? 134 PHE B CE1 1 
ATOM 2696 C CE2 . PHE B 1 134 ? 298.833 306.425 122.124 1.00 12.59  ? 134 PHE B CE2 1 
ATOM 2697 C CZ  . PHE B 1 134 ? 298.303 306.069 123.337 1.00 12.59  ? 134 PHE B CZ  1 
ATOM 2698 N N   . PRO B 1 135 ? 298.781 300.239 119.013 1.00 12.86  ? 135 PRO B N   1 
ATOM 2699 C CA  . PRO B 1 135 ? 298.684 299.519 117.750 1.00 12.86  ? 135 PRO B CA  1 
ATOM 2700 C C   . PRO B 1 135 ? 297.788 300.272 116.794 1.00 12.86  ? 135 PRO B C   1 
ATOM 2701 O O   . PRO B 1 135 ? 297.007 301.132 117.196 1.00 12.86  ? 135 PRO B O   1 
ATOM 2702 C CB  . PRO B 1 135 ? 298.072 298.179 118.153 1.00 12.86  ? 135 PRO B CB  1 
ATOM 2703 C CG  . PRO B 1 135 ? 297.438 298.419 119.436 1.00 12.86  ? 135 PRO B CG  1 
ATOM 2704 C CD  . PRO B 1 135 ? 298.201 299.476 120.124 1.00 12.86  ? 135 PRO B CD  1 
ATOM 2705 N N   . SER B 1 136 ? 297.920 299.943 115.512 1.00 13.27  ? 136 SER B N   1 
ATOM 2706 C CA  . SER B 1 136 ? 297.159 300.620 114.476 1.00 13.27  ? 136 SER B CA  1 
ATOM 2707 C C   . SER B 1 136 ? 295.669 300.389 114.666 1.00 13.27  ? 136 SER B C   1 
ATOM 2708 O O   . SER B 1 136 ? 295.243 299.446 115.331 1.00 13.27  ? 136 SER B O   1 
ATOM 2709 C CB  . SER B 1 136 ? 297.582 300.142 113.099 1.00 13.27  ? 136 SER B CB  1 
ATOM 2710 O OG  . SER B 1 136 ? 296.561 300.404 112.162 1.00 13.27  ? 136 SER B OG  1 
ATOM 2711 N N   . VAL B 1 137 ? 294.871 301.295 114.099 1.00 17.14  ? 137 VAL B N   1 
ATOM 2712 C CA  . VAL B 1 137 ? 293.453 301.333 114.427 1.00 17.14  ? 137 VAL B CA  1 
ATOM 2713 C C   . VAL B 1 137 ? 292.722 300.116 113.875 1.00 17.14  ? 137 VAL B C   1 
ATOM 2714 O O   . VAL B 1 137 ? 291.726 299.686 114.461 1.00 17.14  ? 137 VAL B O   1 
ATOM 2715 C CB  . VAL B 1 137 ? 292.858 302.677 113.955 1.00 17.14  ? 137 VAL B CB  1 
ATOM 2716 C CG1 . VAL B 1 137 ? 292.824 302.767 112.455 1.00 17.14  ? 137 VAL B CG1 1 
ATOM 2717 C CG2 . VAL B 1 137 ? 291.498 302.917 114.559 1.00 17.14  ? 137 VAL B CG2 1 
ATOM 2718 N N   . ARG B 1 138 ? 293.248 299.492 112.818 1.00 27.04  ? 138 ARG B N   1 
ATOM 2719 C CA  . ARG B 1 138 ? 292.740 298.195 112.391 1.00 27.04  ? 138 ARG B CA  1 
ATOM 2720 C C   . ARG B 1 138 ? 292.975 297.136 113.449 1.00 27.04  ? 138 ARG B C   1 
ATOM 2721 O O   . ARG B 1 138 ? 292.104 296.305 113.697 1.00 27.04  ? 138 ARG B O   1 
ATOM 2722 C CB  . ARG B 1 138 ? 293.406 297.770 111.099 1.00 27.04  ? 138 ARG B CB  1 
ATOM 2723 C CG  . ARG B 1 138 ? 293.154 298.687 109.949 1.00 27.04  ? 138 ARG B CG  1 
ATOM 2724 C CD  . ARG B 1 138 ? 293.930 298.220 108.743 1.00 27.04  ? 138 ARG B CD  1 
ATOM 2725 N NE  . ARG B 1 138 ? 293.440 296.941 108.239 1.00 27.04  ? 138 ARG B NE  1 
ATOM 2726 C CZ  . ARG B 1 138 ? 294.100 295.792 108.342 1.00 27.04  ? 138 ARG B CZ  1 
ATOM 2727 N NH1 . ARG B 1 138 ? 293.578 294.680 107.850 1.00 27.04  ? 138 ARG B NH1 1 
ATOM 2728 N NH2 . ARG B 1 138 ? 295.276 295.755 108.951 1.00 27.04  ? 138 ARG B NH2 1 
ATOM 2729 N N   . ASP B 1 139 ? 294.136 297.159 114.094 1.00 16.13  ? 139 ASP B N   1 
ATOM 2730 C CA  . ASP B 1 139 ? 294.450 296.152 115.097 1.00 16.13  ? 139 ASP B CA  1 
ATOM 2731 C C   . ASP B 1 139 ? 293.670 296.360 116.381 1.00 16.13  ? 139 ASP B C   1 
ATOM 2732 O O   . ASP B 1 139 ? 293.251 295.384 117.007 1.00 16.13  ? 139 ASP B O   1 
ATOM 2733 C CB  . ASP B 1 139 ? 295.940 296.158 115.385 1.00 16.13  ? 139 ASP B CB  1 
ATOM 2734 C CG  . ASP B 1 139 ? 296.762 295.973 114.141 1.00 16.13  ? 139 ASP B CG  1 
ATOM 2735 O OD1 . ASP B 1 139 ? 296.172 295.710 113.079 1.00 16.13  ? 139 ASP B OD1 1 
ATOM 2736 O OD2 . ASP B 1 139 ? 298.000 296.070 114.223 1.00 16.13  ? 139 ASP B OD2 1 
ATOM 2737 N N   . LEU B 1 140 ? 293.423 297.611 116.761 1.00 12.56  ? 140 LEU B N   1 
ATOM 2738 C CA  . LEU B 1 140 ? 292.574 297.877 117.915 1.00 12.56  ? 140 LEU B CA  1 
ATOM 2739 C C   . LEU B 1 140 ? 291.123 297.536 117.621 1.00 12.56  ? 140 LEU B C   1 
ATOM 2740 O O   . LEU B 1 140 ? 290.411 297.033 118.493 1.00 12.56  ? 140 LEU B O   1 
ATOM 2741 C CB  . LEU B 1 140 ? 292.698 299.336 118.330 1.00 12.56  ? 140 LEU B CB  1 
ATOM 2742 C CG  . LEU B 1 140 ? 293.978 299.729 119.042 1.00 12.56  ? 140 LEU B CG  1 
ATOM 2743 C CD1 . LEU B 1 140 ? 294.145 301.201 118.993 1.00 12.56  ? 140 LEU B CD1 1 
ATOM 2744 C CD2 . LEU B 1 140 ? 293.937 299.265 120.456 1.00 12.56  ? 140 LEU B CD2 1 
ATOM 2745 N N   . LEU B 1 141 ? 290.673 297.775 116.390 1.00 15.09  ? 141 LEU B N   1 
ATOM 2746 C CA  . LEU B 1 141 ? 289.302 297.440 116.037 1.00 15.09  ? 141 LEU B CA  1 
ATOM 2747 C C   . LEU B 1 141 ? 289.111 295.934 115.923 1.00 15.09  ? 141 LEU B C   1 
ATOM 2748 O O   . LEU B 1 141 ? 288.066 295.407 116.314 1.00 15.09  ? 141 LEU B O   1 
ATOM 2749 C CB  . LEU B 1 141 ? 288.918 298.135 114.736 1.00 15.09  ? 141 LEU B CB  1 
ATOM 2750 C CG  . LEU B 1 141 ? 288.503 299.590 114.899 1.00 15.09  ? 141 LEU B CG  1 
ATOM 2751 C CD1 . LEU B 1 141 ? 288.221 300.235 113.578 1.00 15.09  ? 141 LEU B CD1 1 
ATOM 2752 C CD2 . LEU B 1 141 ? 287.305 299.660 115.768 1.00 15.09  ? 141 LEU B CD2 1 
ATOM 2753 N N   . ASP B 1 142 ? 290.116 295.226 115.406 1.00 15.99  ? 142 ASP B N   1 
ATOM 2754 C CA  . ASP B 1 142 ? 290.063 293.773 115.341 1.00 15.99  ? 142 ASP B CA  1 
ATOM 2755 C C   . ASP B 1 142 ? 290.142 293.154 116.724 1.00 15.99  ? 142 ASP B C   1 
ATOM 2756 O O   . ASP B 1 142 ? 289.509 292.131 116.977 1.00 15.99  ? 142 ASP B O   1 
ATOM 2757 C CB  . ASP B 1 142 ? 291.190 293.246 114.468 1.00 15.99  ? 142 ASP B CB  1 
ATOM 2758 C CG  . ASP B 1 142 ? 290.933 293.460 113.004 1.00 15.99  ? 142 ASP B CG  1 
ATOM 2759 O OD1 . ASP B 1 142 ? 289.922 294.103 112.670 1.00 15.99  ? 142 ASP B OD1 1 
ATOM 2760 O OD2 . ASP B 1 142 ? 291.740 292.984 112.182 1.00 15.99  ? 142 ASP B OD2 1 
ATOM 2761 N N   . THR B 1 143 ? 290.901 293.765 117.634 1.00 10.69  ? 143 THR B N   1 
ATOM 2762 C CA  . THR B 1 143 ? 290.910 293.297 119.011 1.00 10.69  ? 143 THR B CA  1 
ATOM 2763 C C   . THR B 1 143 ? 289.563 293.513 119.671 1.00 10.69  ? 143 THR B C   1 
ATOM 2764 O O   . THR B 1 143 ? 289.054 292.616 120.349 1.00 10.69  ? 143 THR B O   1 
ATOM 2765 C CB  . THR B 1 143 ? 291.999 294.007 119.797 1.00 10.69  ? 143 THR B CB  1 
ATOM 2766 O OG1 . THR B 1 143 ? 293.230 293.939 119.073 1.00 10.69  ? 143 THR B OG1 1 
ATOM 2767 C CG2 . THR B 1 143 ? 292.176 293.364 121.142 1.00 10.69  ? 143 THR B CG2 1 
ATOM 2768 N N   . ALA B 1 144 ? 288.949 294.676 119.432 1.00 10.38  ? 144 ALA B N   1 
ATOM 2769 C CA  . ALA B 1 144 ? 287.651 295.000 120.015 1.00 10.38  ? 144 ALA B CA  1 
ATOM 2770 C C   . ALA B 1 144 ? 286.571 294.062 119.514 1.00 10.38  ? 144 ALA B C   1 
ATOM 2771 O O   . ALA B 1 144 ? 285.842 293.470 120.314 1.00 10.38  ? 144 ALA B O   1 
ATOM 2772 C CB  . ALA B 1 144 ? 287.288 296.443 119.692 1.00 10.38  ? 144 ALA B CB  1 
ATOM 2773 N N   . SER B 1 145 ? 286.489 293.888 118.194 1.00 11.99  ? 145 SER B N   1 
ATOM 2774 C CA  . SER B 1 145 ? 285.602 292.932 117.548 1.00 11.99  ? 145 SER B CA  1 
ATOM 2775 C C   . SER B 1 145 ? 285.828 291.517 118.042 1.00 11.99  ? 145 SER B C   1 
ATOM 2776 O O   . SER B 1 145 ? 285.011 290.992 118.800 1.00 11.99  ? 145 SER B O   1 
ATOM 2777 C CB  . SER B 1 145 ? 285.812 292.979 116.044 1.00 11.99  ? 145 SER B CB  1 
ATOM 2778 O OG  . SER B 1 145 ? 285.362 291.787 115.456 1.00 11.99  ? 145 SER B OG  1 
ATOM 2779 N N   . ALA B 1 146 ? 286.991 290.944 117.737 1.00 12.37  ? 146 ALA B N   1 
ATOM 2780 C CA  . ALA B 1 146 ? 287.326 289.565 118.049 1.00 12.37  ? 146 ALA B CA  1 
ATOM 2781 C C   . ALA B 1 146 ? 287.551 289.299 119.522 1.00 12.37  ? 146 ALA B C   1 
ATOM 2782 O O   . ALA B 1 146 ? 287.980 288.196 119.848 1.00 12.37  ? 146 ALA B O   1 
ATOM 2783 C CB  . ALA B 1 146 ? 288.577 289.168 117.275 1.00 12.37  ? 146 ALA B CB  1 
ATOM 2784 N N   . LEU B 1 147 ? 287.316 290.241 120.425 1.00 10.98  ? 147 LEU B N   1 
ATOM 2785 C CA  . LEU B 1 147 ? 287.422 289.928 121.831 1.00 10.98  ? 147 LEU B CA  1 
ATOM 2786 C C   . LEU B 1 147 ? 286.196 290.347 122.632 1.00 10.98  ? 147 LEU B C   1 
ATOM 2787 O O   . LEU B 1 147 ? 286.003 289.815 123.728 1.00 10.98  ? 147 LEU B O   1 
ATOM 2788 C CB  . LEU B 1 147 ? 288.681 290.591 122.406 1.00 10.98  ? 147 LEU B CB  1 
ATOM 2789 C CG  . LEU B 1 147 ? 289.509 290.006 123.545 1.00 10.98  ? 147 LEU B CG  1 
ATOM 2790 C CD1 . LEU B 1 147 ? 290.919 290.507 123.372 1.00 10.98  ? 147 LEU B CD1 1 
ATOM 2791 C CD2 . LEU B 1 147 ? 289.015 290.347 124.919 1.00 10.98  ? 147 LEU B CD2 1 
ATOM 2792 N N   . TYR B 1 148 ? 285.342 291.258 122.116 1.00 11.77  ? 148 TYR B N   1 
ATOM 2793 C CA  . TYR B 1 148 ? 284.142 291.698 122.822 1.00 11.77  ? 148 TYR B CA  1 
ATOM 2794 C C   . TYR B 1 148 ? 282.951 291.909 121.899 1.00 11.77  ? 148 TYR B C   1 
ATOM 2795 O O   . TYR B 1 148 ? 282.099 292.744 122.204 1.00 11.77  ? 148 TYR B O   1 
ATOM 2796 C CB  . TYR B 1 148 ? 284.355 293.022 123.551 1.00 11.77  ? 148 TYR B CB  1 
ATOM 2797 C CG  . TYR B 1 148 ? 285.485 293.058 124.525 1.00 11.77  ? 148 TYR B CG  1 
ATOM 2798 C CD1 . TYR B 1 148 ? 285.432 292.330 125.701 1.00 11.77  ? 148 TYR B CD1 1 
ATOM 2799 C CD2 . TYR B 1 148 ? 286.598 293.850 124.282 1.00 11.77  ? 148 TYR B CD2 1 
ATOM 2800 C CE1 . TYR B 1 148 ? 286.463 292.366 126.594 1.00 11.77  ? 148 TYR B CE1 1 
ATOM 2801 C CE2 . TYR B 1 148 ? 287.630 293.892 125.164 1.00 11.77  ? 148 TYR B CE2 1 
ATOM 2802 C CZ  . TYR B 1 148 ? 287.553 293.152 126.321 1.00 11.77  ? 148 TYR B CZ  1 
ATOM 2803 O OH  . TYR B 1 148 ? 288.591 293.182 127.207 1.00 11.77  ? 148 TYR B OH  1 
ATOM 2804 N N   . ARG B 1 149 ? 282.870 291.204 120.767 1.00 19.39  ? 149 ARG B N   1 
ATOM 2805 C CA  . ARG B 1 149 ? 281.813 291.494 119.802 1.00 19.39  ? 149 ARG B CA  1 
ATOM 2806 C C   . ARG B 1 149 ? 280.434 291.109 120.310 1.00 19.39  ? 149 ARG B C   1 
ATOM 2807 O O   . ARG B 1 149 ? 279.459 291.802 120.017 1.00 19.39  ? 149 ARG B O   1 
ATOM 2808 C CB  . ARG B 1 149 ? 282.111 290.775 118.497 1.00 19.39  ? 149 ARG B CB  1 
ATOM 2809 C CG  . ARG B 1 149 ? 281.162 291.087 117.386 1.00 19.39  ? 149 ARG B CG  1 
ATOM 2810 C CD  . ARG B 1 149 ? 281.782 290.770 116.067 1.00 19.39  ? 149 ARG B CD  1 
ATOM 2811 N NE  . ARG B 1 149 ? 280.845 290.078 115.203 1.00 19.39  ? 149 ARG B NE  1 
ATOM 2812 C CZ  . ARG B 1 149 ? 280.996 289.956 113.892 1.00 19.39  ? 149 ARG B CZ  1 
ATOM 2813 N NH1 . ARG B 1 149 ? 282.054 290.490 113.299 1.00 19.39  ? 149 ARG B NH1 1 
ATOM 2814 N NH2 . ARG B 1 149 ? 280.094 289.299 113.175 1.00 19.39  ? 149 ARG B NH2 1 
ATOM 2815 N N   . GLU B 1 150 ? 280.329 290.045 121.096 1.00 17.42  ? 150 GLU B N   1 
ATOM 2816 C CA  . GLU B 1 150 ? 279.032 289.661 121.636 1.00 17.42  ? 150 GLU B CA  1 
ATOM 2817 C C   . GLU B 1 150 ? 278.527 290.631 122.686 1.00 17.42  ? 150 GLU B C   1 
ATOM 2818 O O   . GLU B 1 150 ? 277.323 290.679 122.931 1.00 17.42  ? 150 GLU B O   1 
ATOM 2819 C CB  . GLU B 1 150 ? 279.108 288.249 122.214 1.00 17.42  ? 150 GLU B CB  1 
ATOM 2820 C CG  . GLU B 1 150 ? 280.232 288.041 123.222 1.00 17.42  ? 150 GLU B CG  1 
ATOM 2821 C CD  . GLU B 1 150 ? 279.826 288.306 124.656 1.00 17.42  ? 150 GLU B CD  1 
ATOM 2822 O OE1 . GLU B 1 150 ? 278.617 288.239 124.956 1.00 17.42  ? 150 GLU B OE1 1 
ATOM 2823 O OE2 . GLU B 1 150 ? 280.719 288.591 125.480 1.00 17.42  ? 150 GLU B OE2 1 
ATOM 2824 N N   . ALA B 1 151 ? 279.411 291.401 123.312 1.00 13.68  ? 151 ALA B N   1 
ATOM 2825 C CA  . ALA B 1 151 ? 278.998 292.364 124.316 1.00 13.68  ? 151 ALA B CA  1 
ATOM 2826 C C   . ALA B 1 151 ? 278.897 293.773 123.773 1.00 13.68  ? 151 ALA B C   1 
ATOM 2827 O O   . ALA B 1 151 ? 278.196 294.596 124.363 1.00 13.68  ? 151 ALA B O   1 
ATOM 2828 C CB  . ALA B 1 151 ? 279.961 292.346 125.502 1.00 13.68  ? 151 ALA B CB  1 
ATOM 2829 N N   . LEU B 1 152 ? 279.562 294.070 122.668 1.00 13.64  ? 152 LEU B N   1 
ATOM 2830 C CA  . LEU B 1 152 ? 279.376 295.359 122.034 1.00 13.64  ? 152 LEU B CA  1 
ATOM 2831 C C   . LEU B 1 152 ? 278.143 295.404 121.158 1.00 13.64  ? 152 LEU B C   1 
ATOM 2832 O O   . LEU B 1 152 ? 277.767 296.485 120.707 1.00 13.64  ? 152 LEU B O   1 
ATOM 2833 C CB  . LEU B 1 152 ? 280.577 295.728 121.177 1.00 13.64  ? 152 LEU B CB  1 
ATOM 2834 C CG  . LEU B 1 152 ? 281.899 296.067 121.824 1.00 13.64  ? 152 LEU B CG  1 
ATOM 2835 C CD1 . LEU B 1 152 ? 282.846 296.429 120.735 1.00 13.64  ? 152 LEU B CD1 1 
ATOM 2836 C CD2 . LEU B 1 152 ? 281.731 297.193 122.766 1.00 13.64  ? 152 LEU B CD2 1 
ATOM 2837 N N   . GLU B 1 153 ? 277.517 294.272 120.888 1.00 15.19  ? 153 GLU B N   1 
ATOM 2838 C CA  . GLU B 1 153 ? 276.335 294.250 120.051 1.00 15.19  ? 153 GLU B CA  1 
ATOM 2839 C C   . GLU B 1 153 ? 275.085 293.857 120.810 1.00 15.19  ? 153 GLU B C   1 
ATOM 2840 O O   . GLU B 1 153 ? 274.007 293.810 120.215 1.00 15.19  ? 153 GLU B O   1 
ATOM 2841 C CB  . GLU B 1 153 ? 276.551 293.309 118.873 1.00 15.19  ? 153 GLU B CB  1 
ATOM 2842 C CG  . GLU B 1 153 ? 277.681 293.742 117.986 1.00 15.19  ? 153 GLU B CG  1 
ATOM 2843 C CD  . GLU B 1 153 ? 277.502 293.256 116.580 1.00 15.19  ? 153 GLU B CD  1 
ATOM 2844 O OE1 . GLU B 1 153 ? 276.724 292.301 116.382 1.00 15.19  ? 153 GLU B OE1 1 
ATOM 2845 O OE2 . GLU B 1 153 ? 278.129 293.824 115.668 1.00 15.19  ? 153 GLU B OE2 1 
ATOM 2846 N N   . SER B 1 154 ? 275.199 293.583 122.100 1.00 15.21  ? 154 SER B N   1 
ATOM 2847 C CA  . SER B 1 154 ? 274.061 293.256 122.918 1.00 15.21  ? 154 SER B CA  1 
ATOM 2848 C C   . SER B 1 154 ? 273.219 294.504 123.153 1.00 15.21  ? 154 SER B C   1 
ATOM 2849 O O   . SER B 1 154 ? 273.706 295.625 123.006 1.00 15.21  ? 154 SER B O   1 
ATOM 2850 C CB  . SER B 1 154 ? 274.537 292.686 124.244 1.00 15.21  ? 154 SER B CB  1 
ATOM 2851 O OG  . SER B 1 154 ? 275.153 293.694 125.004 1.00 15.21  ? 154 SER B OG  1 
ATOM 2852 N N   . PRO B 1 155 ? 271.943 294.346 123.504 1.00 12.47  ? 155 PRO B N   1 
ATOM 2853 C CA  . PRO B 1 155 ? 271.140 295.504 123.912 1.00 12.47  ? 155 PRO B CA  1 
ATOM 2854 C C   . PRO B 1 155 ? 271.319 295.927 125.362 1.00 12.47  ? 155 PRO B C   1 
ATOM 2855 O O   . PRO B 1 155 ? 270.493 296.691 125.864 1.00 12.47  ? 155 PRO B O   1 
ATOM 2856 C CB  . PRO B 1 155 ? 269.712 295.008 123.677 1.00 12.47  ? 155 PRO B CB  1 
ATOM 2857 C CG  . PRO B 1 155 ? 269.791 293.585 123.880 1.00 12.47  ? 155 PRO B CG  1 
ATOM 2858 C CD  . PRO B 1 155 ? 271.095 293.154 123.328 1.00 12.47  ? 155 PRO B CD  1 
ATOM 2859 N N   . GLU B 1 156 ? 272.358 295.459 126.035 1.00 21.44  ? 156 GLU B N   1 
ATOM 2860 C CA  . GLU B 1 156 ? 272.643 295.808 127.413 1.00 21.44  ? 156 GLU B CA  1 
ATOM 2861 C C   . GLU B 1 156 ? 273.854 296.736 127.445 1.00 21.44  ? 156 GLU B C   1 
ATOM 2862 O O   . GLU B 1 156 ? 274.644 296.787 126.504 1.00 21.44  ? 156 GLU B O   1 
ATOM 2863 C CB  . GLU B 1 156 ? 272.878 294.524 128.217 1.00 21.44  ? 156 GLU B CB  1 
ATOM 2864 C CG  . GLU B 1 156 ? 272.996 294.639 129.739 1.00 21.44  ? 156 GLU B CG  1 
ATOM 2865 C CD  . GLU B 1 156 ? 272.110 295.712 130.344 1.00 21.44  ? 156 GLU B CD  1 
ATOM 2866 O OE1 . GLU B 1 156 ? 272.663 296.640 130.971 1.00 21.44  ? 156 GLU B OE1 1 
ATOM 2867 O OE2 . GLU B 1 156 ? 270.870 295.628 130.207 1.00 21.44  ? 156 GLU B OE2 1 
ATOM 2868 N N   . HIS B 1 157 ? 273.969 297.515 128.517 1.00 20.38  ? 157 HIS B N   1 
ATOM 2869 C CA  . HIS B 1 157 ? 275.135 298.371 128.698 1.00 20.38  ? 157 HIS B CA  1 
ATOM 2870 C C   . HIS B 1 157 ? 276.369 297.553 129.056 1.00 20.38  ? 157 HIS B C   1 
ATOM 2871 O O   . HIS B 1 157 ? 277.374 297.571 128.338 1.00 20.38  ? 157 HIS B O   1 
ATOM 2872 C CB  . HIS B 1 157 ? 274.864 299.389 129.806 1.00 20.38  ? 157 HIS B CB  1 
ATOM 2873 C CG  . HIS B 1 157 ? 273.638 300.217 129.595 1.00 20.38  ? 157 HIS B CG  1 
ATOM 2874 N ND1 . HIS B 1 157 ? 273.486 301.063 128.520 1.00 20.38  ? 157 HIS B ND1 1 
ATOM 2875 C CD2 . HIS B 1 157 ? 272.515 300.346 130.339 1.00 20.38  ? 157 HIS B CD2 1 
ATOM 2876 C CE1 . HIS B 1 157 ? 272.316 301.667 128.605 1.00 20.38  ? 157 HIS B CE1 1 
ATOM 2877 N NE2 . HIS B 1 157 ? 271.708 301.250 129.699 1.00 20.38  ? 157 HIS B NE2 1 
ATOM 2878 N N   . CYS B 1 158 ? 276.302 296.889 130.213 1.00 22.11  ? 158 CYS B N   1 
ATOM 2879 C CA  . CYS B 1 158 ? 277.249 296.008 130.897 1.00 22.11  ? 158 CYS B CA  1 
ATOM 2880 C C   . CYS B 1 158 ? 278.442 296.722 131.519 1.00 22.11  ? 158 CYS B C   1 
ATOM 2881 O O   . CYS B 1 158 ? 279.032 296.182 132.459 1.00 22.11  ? 158 CYS B O   1 
ATOM 2882 C CB  . CYS B 1 158 ? 277.783 294.907 129.969 1.00 22.11  ? 158 CYS B CB  1 
ATOM 2883 S SG  . CYS B 1 158 ? 276.584 294.054 128.924 1.00 22.11  ? 158 CYS B SG  1 
ATOM 2884 N N   . SER B 1 159 ? 278.724 297.965 131.103 1.00 13.94  ? 159 SER B N   1 
ATOM 2885 C CA  . SER B 1 159 ? 279.847 298.788 131.550 1.00 13.94  ? 159 SER B CA  1 
ATOM 2886 C C   . SER B 1 159 ? 279.786 300.134 130.852 1.00 13.94  ? 159 SER B C   1 
ATOM 2887 O O   . SER B 1 159 ? 279.210 300.232 129.765 1.00 13.94  ? 159 SER B O   1 
ATOM 2888 C CB  . SER B 1 159 ? 281.194 298.136 131.239 1.00 13.94  ? 159 SER B CB  1 
ATOM 2889 O OG  . SER B 1 159 ? 281.310 297.856 129.861 1.00 13.94  ? 159 SER B OG  1 
ATOM 2890 N N   . PRO B 1 160 ? 280.376 301.188 131.416 1.00 14.05  ? 160 PRO B N   1 
ATOM 2891 C CA  . PRO B 1 160 ? 280.558 302.420 130.642 1.00 14.05  ? 160 PRO B CA  1 
ATOM 2892 C C   . PRO B 1 160 ? 281.666 302.313 129.620 1.00 14.05  ? 160 PRO B C   1 
ATOM 2893 O O   . PRO B 1 160 ? 281.718 303.120 128.679 1.00 14.05  ? 160 PRO B O   1 
ATOM 2894 C CB  . PRO B 1 160 ? 280.903 303.453 131.708 1.00 14.05  ? 160 PRO B CB  1 
ATOM 2895 C CG  . PRO B 1 160 ? 280.569 302.815 132.995 1.00 14.05  ? 160 PRO B CG  1 
ATOM 2896 C CD  . PRO B 1 160 ? 280.750 301.377 132.819 1.00 14.05  ? 160 PRO B CD  1 
ATOM 2897 N N   . HIS B 1 161 ? 282.543 301.328 129.772 1.00 11.54  ? 161 HIS B N   1 
ATOM 2898 C CA  . HIS B 1 161 ? 283.592 301.112 128.793 1.00 11.54  ? 161 HIS B CA  1 
ATOM 2899 C C   . HIS B 1 161 ? 283.025 300.587 127.495 1.00 11.54  ? 161 HIS B C   1 
ATOM 2900 O O   . HIS B 1 161 ? 283.481 300.970 126.417 1.00 11.54  ? 161 HIS B O   1 
ATOM 2901 C CB  . HIS B 1 161 ? 284.621 300.153 129.355 1.00 11.54  ? 161 HIS B CB  1 
ATOM 2902 C CG  . HIS B 1 161 ? 285.432 300.746 130.448 1.00 11.54  ? 161 HIS B CG  1 
ATOM 2903 N ND1 . HIS B 1 161 ? 286.360 301.735 130.221 1.00 11.54  ? 161 HIS B ND1 1 
ATOM 2904 C CD2 . HIS B 1 161 ? 285.435 300.518 131.778 1.00 11.54  ? 161 HIS B CD2 1 
ATOM 2905 C CE1 . HIS B 1 161 ? 286.902 302.091 131.367 1.00 11.54  ? 161 HIS B CE1 1 
ATOM 2906 N NE2 . HIS B 1 161 ? 286.366 301.361 132.327 1.00 11.54  ? 161 HIS B NE2 1 
ATOM 2907 N N   . HIS B 1 162 ? 282.001 299.742 127.580 1.00 10.83  ? 162 HIS B N   1 
ATOM 2908 C CA  . HIS B 1 162 ? 281.337 299.269 126.375 1.00 10.83  ? 162 HIS B CA  1 
ATOM 2909 C C   . HIS B 1 162 ? 280.584 300.391 125.682 1.00 10.83  ? 162 HIS B C   1 
ATOM 2910 O O   . HIS B 1 162 ? 280.563 300.448 124.453 1.00 10.83  ? 162 HIS B O   1 
ATOM 2911 C CB  . HIS B 1 162 ? 280.400 298.127 126.715 1.00 10.83  ? 162 HIS B CB  1 
ATOM 2912 C CG  . HIS B 1 162 ? 281.094 296.822 126.919 1.00 10.83  ? 162 HIS B CG  1 
ATOM 2913 N ND1 . HIS B 1 162 ? 281.057 296.142 128.115 1.00 10.83  ? 162 HIS B ND1 1 
ATOM 2914 C CD2 . HIS B 1 162 ? 281.836 296.069 126.079 1.00 10.83  ? 162 HIS B CD2 1 
ATOM 2915 C CE1 . HIS B 1 162 ? 281.743 295.023 128.001 1.00 10.83  ? 162 HIS B CE1 1 
ATOM 2916 N NE2 . HIS B 1 162 ? 282.228 294.957 126.776 1.00 10.83  ? 162 HIS B NE2 1 
ATOM 2917 N N   . THR B 1 163 ? 279.995 301.309 126.451 1.00 9.07   ? 163 THR B N   1 
ATOM 2918 C CA  . THR B 1 163 ? 279.267 302.435 125.868 1.00 9.07   ? 163 THR B CA  1 
ATOM 2919 C C   . THR B 1 163 ? 280.206 303.364 125.115 1.00 9.07   ? 163 THR B C   1 
ATOM 2920 O O   . THR B 1 163 ? 279.947 303.733 123.958 1.00 9.07   ? 163 THR B O   1 
ATOM 2921 C CB  . THR B 1 163 ? 278.539 303.202 126.964 1.00 9.07   ? 163 THR B CB  1 
ATOM 2922 O OG1 . THR B 1 163 ? 277.809 302.289 127.784 1.00 9.07   ? 163 THR B OG1 1 
ATOM 2923 C CG2 . THR B 1 163 ? 277.583 304.161 126.374 1.00 9.07   ? 163 THR B CG2 1 
ATOM 2924 N N   . ALA B 1 164 ? 281.320 303.729 125.752 1.00 12.11  ? 164 ALA B N   1 
ATOM 2925 C CA  . ALA B 1 164 ? 282.289 304.587 125.092 1.00 12.11  ? 164 ALA B CA  1 
ATOM 2926 C C   . ALA B 1 164 ? 282.970 303.876 123.936 1.00 12.11  ? 164 ALA B C   1 
ATOM 2927 O O   . ALA B 1 164 ? 283.295 304.514 122.933 1.00 12.11  ? 164 ALA B O   1 
ATOM 2928 C CB  . ALA B 1 164 ? 283.313 305.065 126.100 1.00 12.11  ? 164 ALA B CB  1 
ATOM 2929 N N   . LEU B 1 165 ? 283.128 302.554 124.031 1.00 8.36   ? 165 LEU B N   1 
ATOM 2930 C CA  . LEU B 1 165 ? 283.708 301.767 122.950 1.00 8.36   ? 165 LEU B CA  1 
ATOM 2931 C C   . LEU B 1 165 ? 282.791 301.712 121.733 1.00 8.36   ? 165 LEU B C   1 
ATOM 2932 O O   . LEU B 1 165 ? 283.261 301.821 120.596 1.00 8.36   ? 165 LEU B O   1 
ATOM 2933 C CB  . LEU B 1 165 ? 284.014 300.367 123.469 1.00 8.36   ? 165 LEU B CB  1 
ATOM 2934 C CG  . LEU B 1 165 ? 285.149 299.589 122.825 1.00 8.36   ? 165 LEU B CG  1 
ATOM 2935 C CD1 . LEU B 1 165 ? 286.335 300.469 122.606 1.00 8.36   ? 165 LEU B CD1 1 
ATOM 2936 C CD2 . LEU B 1 165 ? 285.507 298.421 123.689 1.00 8.36   ? 165 LEU B CD2 1 
ATOM 2937 N N   . ARG B 1 166 ? 281.480 301.569 121.958 1.00 9.05   ? 166 ARG B N   1 
ATOM 2938 C CA  . ARG B 1 166 ? 280.506 301.590 120.870 1.00 9.05   ? 166 ARG B CA  1 
ATOM 2939 C C   . ARG B 1 166 ? 280.499 302.933 120.160 1.00 9.05   ? 166 ARG B C   1 
ATOM 2940 O O   . ARG B 1 166 ? 280.536 302.996 118.923 1.00 9.05   ? 166 ARG B O   1 
ATOM 2941 C CB  . ARG B 1 166 ? 279.116 301.289 121.410 1.00 9.05   ? 166 ARG B CB  1 
ATOM 2942 C CG  . ARG B 1 166 ? 278.867 299.867 121.784 1.00 9.05   ? 166 ARG B CG  1 
ATOM 2943 C CD  . ARG B 1 166 ? 277.727 299.794 122.745 1.00 9.05   ? 166 ARG B CD  1 
ATOM 2944 N NE  . ARG B 1 166 ? 277.501 298.451 123.233 1.00 9.05   ? 166 ARG B NE  1 
ATOM 2945 C CZ  . ARG B 1 166 ? 277.056 298.179 124.446 1.00 9.05   ? 166 ARG B CZ  1 
ATOM 2946 N NH1 . ARG B 1 166 ? 276.800 299.155 125.284 1.00 9.05   ? 166 ARG B NH1 1 
ATOM 2947 N NH2 . ARG B 1 166 ? 276.885 296.934 124.829 1.00 9.05   ? 166 ARG B NH2 1 
ATOM 2948 N N   . GLN B 1 167 ? 280.463 304.026 120.931 1.00 10.69  ? 167 GLN B N   1 
ATOM 2949 C CA  . GLN B 1 167 ? 280.477 305.348 120.306 1.00 10.69  ? 167 GLN B CA  1 
ATOM 2950 C C   . GLN B 1 167 ? 281.793 305.641 119.598 1.00 10.69  ? 167 GLN B C   1 
ATOM 2951 O O   . GLN B 1 167 ? 281.786 306.289 118.547 1.00 10.69  ? 167 GLN B O   1 
ATOM 2952 C CB  . GLN B 1 167 ? 280.192 306.436 121.333 1.00 10.69  ? 167 GLN B CB  1 
ATOM 2953 C CG  . GLN B 1 167 ? 278.741 306.827 121.449 1.00 10.69  ? 167 GLN B CG  1 
ATOM 2954 C CD  . GLN B 1 167 ? 277.933 305.806 122.188 1.00 10.69  ? 167 GLN B CD  1 
ATOM 2955 O OE1 . GLN B 1 167 ? 276.919 305.321 121.693 1.00 10.69  ? 167 GLN B OE1 1 
ATOM 2956 N NE2 . GLN B 1 167 ? 278.384 305.454 123.376 1.00 10.69  ? 167 GLN B NE2 1 
ATOM 2957 N N   . ALA B 1 168 ? 282.918 305.142 120.124 1.00 28.56  ? 168 ALA B N   1 
ATOM 2958 C CA  . ALA B 1 168 ? 284.212 305.363 119.483 1.00 28.56  ? 168 ALA B CA  1 
ATOM 2959 C C   . ALA B 1 168 ? 284.321 304.617 118.161 1.00 28.56  ? 168 ALA B C   1 
ATOM 2960 O O   . ALA B 1 168 ? 284.824 305.167 117.171 1.00 28.56  ? 168 ALA B O   1 
ATOM 2961 C CB  . ALA B 1 168 ? 285.330 304.936 120.424 1.00 28.56  ? 168 ALA B CB  1 
ATOM 2962 N N   . ILE B 1 169 ? 283.832 303.372 118.124 1.00 12.34  ? 169 ILE B N   1 
ATOM 2963 C CA  . ILE B 1 169 ? 283.822 302.587 116.893 1.00 12.34  ? 169 ILE B CA  1 
ATOM 2964 C C   . ILE B 1 169 ? 282.946 303.245 115.838 1.00 12.34  ? 169 ILE B C   1 
ATOM 2965 O O   . ILE B 1 169 ? 283.337 303.361 114.669 1.00 12.34  ? 169 ILE B O   1 
ATOM 2966 C CB  . ILE B 1 169 ? 283.366 301.154 117.197 1.00 12.34  ? 169 ILE B CB  1 
ATOM 2967 C CG1 . ILE B 1 169 ? 284.471 300.426 117.939 1.00 12.34  ? 169 ILE B CG1 1 
ATOM 2968 C CG2 . ILE B 1 169 ? 283.037 300.412 115.939 1.00 12.34  ? 169 ILE B CG2 1 
ATOM 2969 C CD1 . ILE B 1 169 ? 284.035 299.211 118.633 1.00 12.34  ? 169 ILE B CD1 1 
ATOM 2970 N N   . LEU B 1 170 ? 281.771 303.733 116.241 1.00 13.24  ? 170 LEU B N   1 
ATOM 2971 C CA  . LEU B 1 170 ? 280.888 304.369 115.270 1.00 13.24  ? 170 LEU B CA  1 
ATOM 2972 C C   . LEU B 1 170 ? 281.421 305.708 114.792 1.00 13.24  ? 170 LEU B C   1 
ATOM 2973 O O   . LEU B 1 170 ? 281.202 306.073 113.631 1.00 13.24  ? 170 LEU B O   1 
ATOM 2974 C CB  . LEU B 1 170 ? 279.509 304.541 115.868 1.00 13.24  ? 170 LEU B CB  1 
ATOM 2975 C CG  . LEU B 1 170 ? 278.847 303.189 115.949 1.00 13.24  ? 170 LEU B CG  1 
ATOM 2976 C CD1 . LEU B 1 170 ? 277.854 303.233 117.026 1.00 13.24  ? 170 LEU B CD1 1 
ATOM 2977 C CD2 . LEU B 1 170 ? 278.187 302.920 114.637 1.00 13.24  ? 170 LEU B CD2 1 
ATOM 2978 N N   . ALA B 1 171 ? 282.131 306.442 115.653 1.00 14.87  ? 171 ALA B N   1 
ATOM 2979 C CA  . ALA B 1 171 ? 282.746 307.693 115.229 1.00 14.87  ? 171 ALA B CA  1 
ATOM 2980 C C   . ALA B 1 171 ? 283.848 307.446 114.218 1.00 14.87  ? 171 ALA B C   1 
ATOM 2981 O O   . ALA B 1 171 ? 283.958 308.176 113.225 1.00 14.87  ? 171 ALA B O   1 
ATOM 2982 C CB  . ALA B 1 171 ? 283.292 308.438 116.436 1.00 14.87  ? 171 ALA B CB  1 
ATOM 2983 N N   . TRP B 1 172 ? 284.650 306.399 114.431 1.00 19.74  ? 172 TRP B N   1 
ATOM 2984 C CA  . TRP B 1 172 ? 285.675 306.073 113.448 1.00 19.74  ? 172 TRP B CA  1 
ATOM 2985 C C   . TRP B 1 172 ? 285.063 305.590 112.141 1.00 19.74  ? 172 TRP B C   1 
ATOM 2986 O O   . TRP B 1 172 ? 285.588 305.883 111.063 1.00 19.74  ? 172 TRP B O   1 
ATOM 2987 C CB  . TRP B 1 172 ? 286.642 305.027 113.984 1.00 19.74  ? 172 TRP B CB  1 
ATOM 2988 C CG  . TRP B 1 172 ? 287.672 304.695 112.967 1.00 19.74  ? 172 TRP B CG  1 
ATOM 2989 C CD1 . TRP B 1 172 ? 287.780 303.541 112.267 1.00 19.74  ? 172 TRP B CD1 1 
ATOM 2990 C CD2 . TRP B 1 172 ? 288.713 305.552 112.489 1.00 19.74  ? 172 TRP B CD2 1 
ATOM 2991 N NE1 . TRP B 1 172 ? 288.833 303.610 111.399 1.00 19.74  ? 172 TRP B NE1 1 
ATOM 2992 C CE2 . TRP B 1 172 ? 289.424 304.838 111.519 1.00 19.74  ? 172 TRP B CE2 1 
ATOM 2993 C CE3 . TRP B 1 172 ? 289.126 306.846 112.805 1.00 19.74  ? 172 TRP B CE3 1 
ATOM 2994 C CZ2 . TRP B 1 172 ? 290.513 305.373 110.857 1.00 19.74  ? 172 TRP B CZ2 1 
ATOM 2995 C CZ3 . TRP B 1 172 ? 290.201 307.371 112.146 1.00 19.74  ? 172 TRP B CZ3 1 
ATOM 2996 C CH2 . TRP B 1 172 ? 290.883 306.639 111.185 1.00 19.74  ? 172 TRP B CH2 1 
ATOM 2997 N N   . GLY B 1 173 ? 283.946 304.866 112.213 1.00 19.72  ? 173 GLY B N   1 
ATOM 2998 C CA  . GLY B 1 173 ? 283.277 304.443 110.994 1.00 19.72  ? 173 GLY B CA  1 
ATOM 2999 C C   . GLY B 1 173 ? 282.728 305.608 110.196 1.00 19.72  ? 173 GLY B C   1 
ATOM 3000 O O   . GLY B 1 173 ? 282.865 305.649 108.970 1.00 19.72  ? 173 GLY B O   1 
ATOM 3001 N N   . GLU B 1 174 ? 282.120 306.577 110.884 1.00 20.51  ? 174 GLU B N   1 
ATOM 3002 C CA  . GLU B 1 174 ? 281.637 307.785 110.225 1.00 20.51  ? 174 GLU B CA  1 
ATOM 3003 C C   . GLU B 1 174 ? 282.771 308.568 109.596 1.00 20.51  ? 174 GLU B C   1 
ATOM 3004 O O   . GLU B 1 174 ? 282.612 309.125 108.507 1.00 20.51  ? 174 GLU B O   1 
ATOM 3005 C CB  . GLU B 1 174 ? 280.901 308.672 111.224 1.00 20.51  ? 174 GLU B CB  1 
ATOM 3006 C CG  . GLU B 1 174 ? 279.526 308.188 111.586 1.00 20.51  ? 174 GLU B CG  1 
ATOM 3007 C CD  . GLU B 1 174 ? 278.633 308.059 110.380 1.00 20.51  ? 174 GLU B CD  1 
ATOM 3008 O OE1 . GLU B 1 174 ? 277.983 307.003 110.233 1.00 20.51  ? 174 GLU B OE1 1 
ATOM 3009 O OE2 . GLU B 1 174 ? 278.582 309.011 109.576 1.00 20.51  ? 174 GLU B OE2 1 
ATOM 3010 N N   . LEU B 1 175 ? 283.925 308.596 110.251 1.00 22.57  ? 175 LEU B N   1 
ATOM 3011 C CA  . LEU B 1 175 ? 285.079 309.289 109.699 1.00 22.57  ? 175 LEU B CA  1 
ATOM 3012 C C   . LEU B 1 175 ? 285.671 308.543 108.508 1.00 22.57  ? 175 LEU B C   1 
ATOM 3013 O O   . LEU B 1 175 ? 286.184 309.165 107.567 1.00 22.57  ? 175 LEU B O   1 
ATOM 3014 C CB  . LEU B 1 175 ? 286.099 309.470 110.814 1.00 22.57  ? 175 LEU B CB  1 
ATOM 3015 C CG  . LEU B 1 175 ? 287.118 310.576 110.728 1.00 22.57  ? 175 LEU B CG  1 
ATOM 3016 C CD1 . LEU B 1 175 ? 287.303 311.129 112.108 1.00 22.57  ? 175 LEU B CD1 1 
ATOM 3017 C CD2 . LEU B 1 175 ? 288.390 309.981 110.238 1.00 22.57  ? 175 LEU B CD2 1 
ATOM 3018 N N   . MET B 1 176 ? 285.564 307.215 108.505 1.00 28.00  ? 176 MET B N   1 
ATOM 3019 C CA  . MET B 1 176 ? 286.078 306.446 107.382 1.00 28.00  ? 176 MET B CA  1 
ATOM 3020 C C   . MET B 1 176 ? 285.177 306.544 106.160 1.00 28.00  ? 176 MET B C   1 
ATOM 3021 O O   . MET B 1 176 ? 285.670 306.450 105.031 1.00 28.00  ? 176 MET B O   1 
ATOM 3022 C CB  . MET B 1 176 ? 286.271 304.989 107.781 1.00 28.00  ? 176 MET B CB  1 
ATOM 3023 C CG  . MET B 1 176 ? 287.617 304.723 108.406 1.00 28.00  ? 176 MET B CG  1 
ATOM 3024 S SD  . MET B 1 176 ? 288.941 305.636 107.594 1.00 28.00  ? 176 MET B SD  1 
ATOM 3025 C CE  . MET B 1 176 ? 289.103 304.706 106.074 1.00 28.00  ? 176 MET B CE  1 
ATOM 3026 N N   . THR B 1 177 ? 283.867 306.731 106.350 1.00 24.98  ? 177 THR B N   1 
ATOM 3027 C CA  . THR B 1 177 ? 283.024 307.024 105.189 1.00 24.98  ? 177 THR B CA  1 
ATOM 3028 C C   . THR B 1 177 ? 283.381 308.361 104.558 1.00 24.98  ? 177 THR B C   1 
ATOM 3029 O O   . THR B 1 177 ? 283.290 308.506 103.338 1.00 24.98  ? 177 THR B O   1 
ATOM 3030 C CB  . THR B 1 177 ? 281.539 307.020 105.539 1.00 24.98  ? 177 THR B CB  1 
ATOM 3031 O OG1 . THR B 1 177 ? 281.234 308.164 106.342 1.00 24.98  ? 177 THR B OG1 1 
ATOM 3032 C CG2 . THR B 1 177 ? 281.131 305.752 106.242 1.00 24.98  ? 177 THR B CG2 1 
ATOM 3033 N N   . LEU B 1 178 ? 283.815 309.331 105.360 1.00 25.87  ? 178 LEU B N   1 
ATOM 3034 C CA  . LEU B 1 178 ? 284.320 310.584 104.809 1.00 25.87  ? 178 LEU B CA  1 
ATOM 3035 C C   . LEU B 1 178 ? 285.610 310.368 104.044 1.00 25.87  ? 178 LEU B C   1 
ATOM 3036 O O   . LEU B 1 178 ? 285.804 310.953 102.973 1.00 25.87  ? 178 LEU B O   1 
ATOM 3037 C CB  . LEU B 1 178 ? 284.545 311.591 105.927 1.00 25.87  ? 178 LEU B CB  1 
ATOM 3038 C CG  . LEU B 1 178 ? 285.410 312.820 105.668 1.00 25.87  ? 178 LEU B CG  1 
ATOM 3039 C CD1 . LEU B 1 178 ? 284.842 313.720 104.600 1.00 25.87  ? 178 LEU B CD1 1 
ATOM 3040 C CD2 . LEU B 1 178 ? 285.516 313.568 106.942 1.00 25.87  ? 178 LEU B CD2 1 
ATOM 3041 N N   . ALA B 1 179 ? 286.508 309.546 104.596 1.00 31.47  ? 179 ALA B N   1 
ATOM 3042 C CA  . ALA B 1 179 ? 287.769 309.245 103.920 1.00 31.47  ? 179 ALA B CA  1 
ATOM 3043 C C   . ALA B 1 179 ? 287.539 308.527 102.596 1.00 31.47  ? 179 ALA B C   1 
ATOM 3044 O O   . ALA B 1 179 ? 288.297 308.713 101.638 1.00 31.47  ? 179 ALA B O   1 
ATOM 3045 C CB  . ALA B 1 179 ? 288.659 308.408 104.833 1.00 31.47  ? 179 ALA B CB  1 
ATOM 3046 N N   . THR B 1 180 ? 286.494 307.704 102.524 1.00 35.06  ? 180 THR B N   1 
ATOM 3047 C CA  . THR B 1 180 ? 286.104 307.099 101.255 1.00 35.06  ? 180 THR B CA  1 
ATOM 3048 C C   . THR B 1 180 ? 285.495 308.134 100.313 1.00 35.06  ? 180 THR B C   1 
ATOM 3049 O O   . THR B 1 180 ? 285.807 308.147 99.117  1.00 35.06  ? 180 THR B O   1 
ATOM 3050 C CB  . THR B 1 180 ? 285.128 305.954 101.521 1.00 35.06  ? 180 THR B CB  1 
ATOM 3051 O OG1 . THR B 1 180 ? 285.807 304.914 102.231 1.00 35.06  ? 180 THR B OG1 1 
ATOM 3052 C CG2 . THR B 1 180 ? 284.575 305.383 100.237 1.00 35.06  ? 180 THR B CG2 1 
ATOM 3053 N N   . TRP B 1 181 ? 284.649 309.026 100.846 1.00 39.71  ? 181 TRP B N   1 
ATOM 3054 C CA  . TRP B 1 181 ? 283.942 310.005 100.025 1.00 39.71  ? 181 TRP B CA  1 
ATOM 3055 C C   . TRP B 1 181 ? 284.892 310.995 99.374  1.00 39.71  ? 181 TRP B C   1 
ATOM 3056 O O   . TRP B 1 181 ? 284.655 311.434 98.244  1.00 39.71  ? 181 TRP B O   1 
ATOM 3057 C CB  . TRP B 1 181 ? 282.921 310.764 100.874 1.00 39.71  ? 181 TRP B CB  1 
ATOM 3058 C CG  . TRP B 1 181 ? 282.136 311.814 100.118 1.00 39.71  ? 181 TRP B CG  1 
ATOM 3059 C CD1 . TRP B 1 181 ? 280.931 311.645 99.515  1.00 39.71  ? 181 TRP B CD1 1 
ATOM 3060 C CD2 . TRP B 1 181 ? 282.499 313.187 99.905  1.00 39.71  ? 181 TRP B CD2 1 
ATOM 3061 N NE1 . TRP B 1 181 ? 280.522 312.816 98.931  1.00 39.71  ? 181 TRP B NE1 1 
ATOM 3062 C CE2 . TRP B 1 181 ? 281.470 313.777 99.153  1.00 39.71  ? 181 TRP B CE2 1 
ATOM 3063 C CE3 . TRP B 1 181 ? 283.598 313.969 100.267 1.00 39.71  ? 181 TRP B CE3 1 
ATOM 3064 C CZ2 . TRP B 1 181 ? 281.502 315.108 98.763  1.00 39.71  ? 181 TRP B CZ2 1 
ATOM 3065 C CZ3 . TRP B 1 181 ? 283.629 315.287 99.876  1.00 39.71  ? 181 TRP B CZ3 1 
ATOM 3066 C CH2 . TRP B 1 181 ? 282.589 315.846 99.133  1.00 39.71  ? 181 TRP B CH2 1 
ATOM 3067 N N   . VAL B 1 182 ? 285.949 311.394 100.082 1.00 42.80  ? 182 VAL B N   1 
ATOM 3068 C CA  . VAL B 1 182 ? 286.831 312.419 99.534  1.00 42.80  ? 182 VAL B CA  1 
ATOM 3069 C C   . VAL B 1 182 ? 287.681 311.837 98.408  1.00 42.80  ? 182 VAL B C   1 
ATOM 3070 O O   . VAL B 1 182 ? 288.050 312.546 97.465  1.00 42.80  ? 182 VAL B O   1 
ATOM 3071 C CB  . VAL B 1 182 ? 287.661 313.048 100.671 1.00 42.80  ? 182 VAL B CB  1 
ATOM 3072 C CG1 . VAL B 1 182 ? 288.477 312.007 101.381 1.00 42.80  ? 182 VAL B CG1 1 
ATOM 3073 C CG2 . VAL B 1 182 ? 288.527 314.201 100.182 1.00 42.80  ? 182 VAL B CG2 1 
ATOM 3074 N N   . GLY B 1 183 ? 287.938 310.529 98.439  1.00 49.14  ? 183 GLY B N   1 
ATOM 3075 C CA  . GLY B 1 183 ? 288.506 309.867 97.280  1.00 49.14  ? 183 GLY B CA  1 
ATOM 3076 C C   . GLY B 1 183 ? 287.506 309.623 96.170  1.00 49.14  ? 183 GLY B C   1 
ATOM 3077 O O   . GLY B 1 183 ? 287.916 309.358 95.035  1.00 49.14  ? 183 GLY B O   1 
ATOM 3078 N N   . ASN B 1 184 ? 286.209 309.717 96.481  1.00 52.77  ? 184 ASN B N   1 
ATOM 3079 C CA  . ASN B 1 184 ? 285.079 309.525 95.562  1.00 52.77  ? 184 ASN B CA  1 
ATOM 3080 C C   . ASN B 1 184 ? 285.119 308.184 94.840  1.00 52.77  ? 184 ASN B C   1 
ATOM 3081 O O   . ASN B 1 184 ? 285.408 307.157 95.452  1.00 52.77  ? 184 ASN B O   1 
ATOM 3082 C CB  . ASN B 1 184 ? 285.006 310.670 94.547  1.00 52.77  ? 184 ASN B CB  1 
ATOM 3083 C CG  . ASN B 1 184 ? 284.420 311.937 95.140  1.00 52.77  ? 184 ASN B CG  1 
ATOM 3084 O OD1 . ASN B 1 184 ? 283.259 312.270 94.904  1.00 52.77  ? 184 ASN B OD1 1 
ATOM 3085 N ND2 . ASN B 1 184 ? 285.223 312.650 95.919  1.00 52.77  ? 184 ASN B ND2 1 
ATOM 3086 N N   . PRO B 1 194 ? 293.581 315.202 92.791  1.00 80.09  ? 194 PRO B N   1 
ATOM 3087 C CA  . PRO B 1 194 ? 295.013 315.500 92.902  1.00 80.09  ? 194 PRO B CA  1 
ATOM 3088 C C   . PRO B 1 194 ? 295.600 315.052 94.235  1.00 80.09  ? 194 PRO B C   1 
ATOM 3089 O O   . PRO B 1 194 ? 295.184 314.031 94.775  1.00 80.09  ? 194 PRO B O   1 
ATOM 3090 C CB  . PRO B 1 194 ? 295.068 317.025 92.765  1.00 80.09  ? 194 PRO B CB  1 
ATOM 3091 C CG  . PRO B 1 194 ? 293.701 317.495 93.130  1.00 80.09  ? 194 PRO B CG  1 
ATOM 3092 C CD  . PRO B 1 194 ? 292.769 316.424 92.666  1.00 80.09  ? 194 PRO B CD  1 
ATOM 3093 N N   . ALA B 1 195 ? 296.562 315.812 94.755  1.00 71.64  ? 195 ALA B N   1 
ATOM 3094 C CA  . ALA B 1 195 ? 297.184 315.498 96.033  1.00 71.64  ? 195 ALA B CA  1 
ATOM 3095 C C   . ALA B 1 195 ? 296.469 316.131 97.216  1.00 71.64  ? 195 ALA B C   1 
ATOM 3096 O O   . ALA B 1 195 ? 296.806 315.812 98.362  1.00 71.64  ? 195 ALA B O   1 
ATOM 3097 C CB  . ALA B 1 195 ? 298.650 315.939 96.034  1.00 71.64  ? 195 ALA B CB  1 
ATOM 3098 N N   . SER B 1 196 ? 295.497 317.013 96.965  1.00 65.90  ? 196 SER B N   1 
ATOM 3099 C CA  . SER B 1 196 ? 294.761 317.658 98.049  1.00 65.90  ? 196 SER B CA  1 
ATOM 3100 C C   . SER B 1 196 ? 293.903 316.656 98.808  1.00 65.90  ? 196 SER B C   1 
ATOM 3101 O O   . SER B 1 196 ? 293.943 316.603 100.045 1.00 65.90  ? 196 SER B O   1 
ATOM 3102 C CB  . SER B 1 196 ? 293.896 318.786 97.492  1.00 65.90  ? 196 SER B CB  1 
ATOM 3103 O OG  . SER B 1 196 ? 292.880 318.271 96.650  1.00 65.90  ? 196 SER B OG  1 
ATOM 3104 N N   . ARG B 1 197 ? 293.133 315.841 98.084  1.00 66.56  ? 197 ARG B N   1 
ATOM 3105 C CA  . ARG B 1 197 ? 292.393 314.766 98.731  1.00 66.56  ? 197 ARG B CA  1 
ATOM 3106 C C   . ARG B 1 197 ? 293.333 313.728 99.325  1.00 66.56  ? 197 ARG B C   1 
ATOM 3107 O O   . ARG B 1 197 ? 293.024 313.136 100.364 1.00 66.56  ? 197 ARG B O   1 
ATOM 3108 C CB  . ARG B 1 197 ? 291.430 314.112 97.739  1.00 66.56  ? 197 ARG B CB  1 
ATOM 3109 C CG  . ARG B 1 197 ? 291.988 313.930 96.340  1.00 66.56  ? 197 ARG B CG  1 
ATOM 3110 C CD  . ARG B 1 197 ? 290.879 313.661 95.341  1.00 66.56  ? 197 ARG B CD  1 
ATOM 3111 N NE  . ARG B 1 197 ? 289.968 314.794 95.225  1.00 66.56  ? 197 ARG B NE  1 
ATOM 3112 C CZ  . ARG B 1 197 ? 288.984 314.876 94.335  1.00 66.56  ? 197 ARG B CZ  1 
ATOM 3113 N NH1 . ARG B 1 197 ? 288.782 313.886 93.478  1.00 66.56  ? 197 ARG B NH1 1 
ATOM 3114 N NH2 . ARG B 1 197 ? 288.203 315.947 94.303  1.00 66.56  ? 197 ARG B NH2 1 
ATOM 3115 N N   . ASP B 1 198 ? 294.499 313.535 98.707  1.00 69.46  ? 198 ASP B N   1 
ATOM 3116 C CA  . ASP B 1 198 ? 295.469 312.574 99.204  1.00 69.46  ? 198 ASP B CA  1 
ATOM 3117 C C   . ASP B 1 198 ? 296.096 313.008 100.519 1.00 69.46  ? 198 ASP B C   1 
ATOM 3118 O O   . ASP B 1 198 ? 296.506 312.149 101.305 1.00 69.46  ? 198 ASP B O   1 
ATOM 3119 C CB  . ASP B 1 198 ? 296.551 312.348 98.154  1.00 69.46  ? 198 ASP B CB  1 
ATOM 3120 C CG  . ASP B 1 198 ? 296.161 311.296 97.137  1.00 69.46  ? 198 ASP B CG  1 
ATOM 3121 O OD1 . ASP B 1 198 ? 294.948 311.105 96.911  1.00 69.46  ? 198 ASP B OD1 1 
ATOM 3122 O OD2 . ASP B 1 198 ? 297.069 310.666 96.559  1.00 69.46  ? 198 ASP B OD2 1 
ATOM 3123 N N   . LEU B 1 199 ? 296.179 314.309 100.783 1.00 55.07  ? 199 LEU B N   1 
ATOM 3124 C CA  . LEU B 1 199 ? 296.628 314.743 102.099 1.00 55.07  ? 199 LEU B CA  1 
ATOM 3125 C C   . LEU B 1 199 ? 295.477 314.912 103.080 1.00 55.07  ? 199 LEU B C   1 
ATOM 3126 O O   . LEU B 1 199 ? 295.701 314.847 104.292 1.00 55.07  ? 199 LEU B O   1 
ATOM 3127 C CB  . LEU B 1 199 ? 297.444 316.039 101.993 1.00 55.07  ? 199 LEU B CB  1 
ATOM 3128 C CG  . LEU B 1 199 ? 296.883 317.324 101.383 1.00 55.07  ? 199 LEU B CG  1 
ATOM 3129 C CD1 . LEU B 1 199 ? 296.324 318.251 102.441 1.00 55.07  ? 199 LEU B CD1 1 
ATOM 3130 C CD2 . LEU B 1 199 ? 297.954 318.031 100.577 1.00 55.07  ? 199 LEU B CD2 1 
ATOM 3131 N N   . VAL B 1 200 ? 294.249 315.102 102.590 1.00 50.44  ? 200 VAL B N   1 
ATOM 3132 C CA  . VAL B 1 200 ? 293.100 315.100 103.494 1.00 50.44  ? 200 VAL B CA  1 
ATOM 3133 C C   . VAL B 1 200 ? 292.875 313.711 104.094 1.00 50.44  ? 200 VAL B C   1 
ATOM 3134 O O   . VAL B 1 200 ? 292.617 313.592 105.301 1.00 50.44  ? 200 VAL B O   1 
ATOM 3135 C CB  . VAL B 1 200 ? 291.854 315.629 102.760 1.00 50.44  ? 200 VAL B CB  1 
ATOM 3136 C CG1 . VAL B 1 200 ? 290.571 315.271 103.488 1.00 50.44  ? 200 VAL B CG1 1 
ATOM 3137 C CG2 . VAL B 1 200 ? 291.941 317.133 102.612 1.00 50.44  ? 200 VAL B CG2 1 
ATOM 3138 N N   . VAL B 1 201 ? 293.002 312.653 103.283 1.00 43.12  ? 201 VAL B N   1 
ATOM 3139 C CA  . VAL B 1 201 ? 292.941 311.281 103.799 1.00 43.12  ? 201 VAL B CA  1 
ATOM 3140 C C   . VAL B 1 201 ? 294.070 311.031 104.793 1.00 43.12  ? 201 VAL B C   1 
ATOM 3141 O O   . VAL B 1 201 ? 293.878 310.372 105.824 1.00 43.12  ? 201 VAL B O   1 
ATOM 3142 C CB  . VAL B 1 201 ? 292.977 310.267 102.638 1.00 43.12  ? 201 VAL B CB  1 
ATOM 3143 C CG1 . VAL B 1 201 ? 292.940 308.845 103.151 1.00 43.12  ? 201 VAL B CG1 1 
ATOM 3144 C CG2 . VAL B 1 201 ? 291.810 310.470 101.722 1.00 43.12  ? 201 VAL B CG2 1 
ATOM 3145 N N   . ASN B 1 202 ? 295.249 311.599 104.523 1.00 44.68  ? 202 ASN B N   1 
ATOM 3146 C CA  . ASN B 1 202 ? 296.379 311.464 105.434 1.00 44.68  ? 202 ASN B CA  1 
ATOM 3147 C C   . ASN B 1 202 ? 296.094 312.132 106.772 1.00 44.68  ? 202 ASN B C   1 
ATOM 3148 O O   . ASN B 1 202 ? 296.405 311.568 107.829 1.00 44.68  ? 202 ASN B O   1 
ATOM 3149 C CB  . ASN B 1 202 ? 297.628 312.065 104.796 1.00 44.68  ? 202 ASN B CB  1 
ATOM 3150 C CG  . ASN B 1 202 ? 298.874 311.823 105.616 1.00 44.68  ? 202 ASN B CG  1 
ATOM 3151 O OD1 . ASN B 1 202 ? 298.918 310.916 106.445 1.00 44.68  ? 202 ASN B OD1 1 
ATOM 3152 N ND2 . ASN B 1 202 ? 299.894 312.645 105.400 1.00 44.68  ? 202 ASN B ND2 1 
ATOM 3153 N N   . TYR B 1 203 ? 295.487 313.324 106.738 1.00 38.72  ? 203 TYR B N   1 
ATOM 3154 C CA  . TYR B 1 203 ? 295.096 314.013 107.964 1.00 38.72  ? 203 TYR B CA  1 
ATOM 3155 C C   . TYR B 1 203 ? 294.098 313.189 108.759 1.00 38.72  ? 203 TYR B C   1 
ATOM 3156 O O   . TYR B 1 203 ? 294.296 312.940 109.953 1.00 38.72  ? 203 TYR B O   1 
ATOM 3157 C CB  . TYR B 1 203 ? 294.504 315.388 107.647 1.00 38.72  ? 203 TYR B CB  1 
ATOM 3158 C CG  . TYR B 1 203 ? 294.062 316.142 108.888 1.00 38.72  ? 203 TYR B CG  1 
ATOM 3159 C CD1 . TYR B 1 203 ? 294.977 316.836 109.656 1.00 38.72  ? 203 TYR B CD1 1 
ATOM 3160 C CD2 . TYR B 1 203 ? 292.731 316.151 109.295 1.00 38.72  ? 203 TYR B CD2 1 
ATOM 3161 C CE1 . TYR B 1 203 ? 294.582 317.516 110.786 1.00 38.72  ? 203 TYR B CE1 1 
ATOM 3162 C CE2 . TYR B 1 203 ? 292.338 316.812 110.431 1.00 38.72  ? 203 TYR B CE2 1 
ATOM 3163 C CZ  . TYR B 1 203 ? 293.265 317.492 111.167 1.00 38.72  ? 203 TYR B CZ  1 
ATOM 3164 O OH  . TYR B 1 203 ? 292.875 318.163 112.292 1.00 38.72  ? 203 TYR B OH  1 
ATOM 3165 N N   . VAL B 1 204 ? 293.027 312.735 108.106 1.00 32.44  ? 204 VAL B N   1 
ATOM 3166 C CA  . VAL B 1 204 ? 291.981 312.028 108.832 1.00 32.44  ? 204 VAL B CA  1 
ATOM 3167 C C   . VAL B 1 204 ? 292.390 310.628 109.241 1.00 32.44  ? 204 VAL B C   1 
ATOM 3168 O O   . VAL B 1 204 ? 291.681 310.002 110.029 1.00 32.44  ? 204 VAL B O   1 
ATOM 3169 C CB  . VAL B 1 204 ? 290.663 311.949 108.034 1.00 32.44  ? 204 VAL B CB  1 
ATOM 3170 C CG1 . VAL B 1 204 ? 290.239 313.321 107.568 1.00 32.44  ? 204 VAL B CG1 1 
ATOM 3171 C CG2 . VAL B 1 204 ? 290.783 311.004 106.874 1.00 32.44  ? 204 VAL B CG2 1 
ATOM 3172 N N   . ASN B 1 205 ? 293.510 310.114 108.733 1.00 33.15  ? 205 ASN B N   1 
ATOM 3173 C CA  . ASN B 1 205 ? 294.015 308.842 109.232 1.00 33.15  ? 205 ASN B CA  1 
ATOM 3174 C C   . ASN B 1 205 ? 295.027 308.999 110.354 1.00 33.15  ? 205 ASN B C   1 
ATOM 3175 O O   . ASN B 1 205 ? 295.057 308.160 111.259 1.00 33.15  ? 205 ASN B O   1 
ATOM 3176 C CB  . ASN B 1 205 ? 294.640 308.033 108.100 1.00 33.15  ? 205 ASN B CB  1 
ATOM 3177 C CG  . ASN B 1 205 ? 293.612 307.484 107.157 1.00 33.15  ? 205 ASN B CG  1 
ATOM 3178 O OD1 . ASN B 1 205 ? 292.457 307.303 107.525 1.00 33.15  ? 205 ASN B OD1 1 
ATOM 3179 N ND2 . ASN B 1 205 ? 294.022 307.207 105.932 1.00 33.15  ? 205 ASN B ND2 1 
ATOM 3180 N N   . THR B 1 206 ? 295.860 310.041 110.335 1.00 34.88  ? 206 THR B N   1 
ATOM 3181 C CA  . THR B 1 206 ? 296.845 310.216 111.398 1.00 34.88  ? 206 THR B CA  1 
ATOM 3182 C C   . THR B 1 206 ? 296.345 311.094 112.540 1.00 34.88  ? 206 THR B C   1 
ATOM 3183 O O   . THR B 1 206 ? 296.241 310.614 113.674 1.00 34.88  ? 206 THR B O   1 
ATOM 3184 C CB  . THR B 1 206 ? 298.142 310.795 110.842 1.00 34.88  ? 206 THR B CB  1 
ATOM 3185 O OG1 . THR B 1 206 ? 297.941 312.173 110.512 1.00 34.88  ? 206 THR B OG1 1 
ATOM 3186 C CG2 . THR B 1 206 ? 298.597 310.014 109.636 1.00 34.88  ? 206 THR B CG2 1 
ATOM 3187 N N   . ASN B 1 207 ? 296.003 312.358 112.252 1.00 33.97  ? 207 ASN B N   1 
ATOM 3188 C CA  . ASN B 1 207 ? 295.847 313.364 113.304 1.00 33.97  ? 207 ASN B CA  1 
ATOM 3189 C C   . ASN B 1 207 ? 294.623 313.094 114.166 1.00 33.97  ? 207 ASN B C   1 
ATOM 3190 O O   . ASN B 1 207 ? 294.731 312.959 115.388 1.00 33.97  ? 207 ASN B O   1 
ATOM 3191 C CB  . ASN B 1 207 ? 295.771 314.751 112.686 1.00 33.97  ? 207 ASN B CB  1 
ATOM 3192 C CG  . ASN B 1 207 ? 296.985 315.077 111.861 1.00 33.97  ? 207 ASN B CG  1 
ATOM 3193 O OD1 . ASN B 1 207 ? 297.119 314.622 110.729 1.00 33.97  ? 207 ASN B OD1 1 
ATOM 3194 N ND2 . ASN B 1 207 ? 297.880 315.875 112.421 1.00 33.97  ? 207 ASN B ND2 1 
ATOM 3195 N N   . MET B 1 208 ? 293.451 313.025 113.558 1.00 31.00  ? 208 MET B N   1 
ATOM 3196 C CA  . MET B 1 208 ? 292.363 312.276 114.155 1.00 31.00  ? 208 MET B CA  1 
ATOM 3197 C C   . MET B 1 208 ? 292.562 310.832 113.752 1.00 31.00  ? 208 MET B C   1 
ATOM 3198 O O   . MET B 1 208 ? 292.937 310.538 112.617 1.00 31.00  ? 208 MET B O   1 
ATOM 3199 C CB  . MET B 1 208 ? 290.993 312.780 113.712 1.00 31.00  ? 208 MET B CB  1 
ATOM 3200 C CG  . MET B 1 208 ? 290.876 313.070 112.246 1.00 31.00  ? 208 MET B CG  1 
ATOM 3201 S SD  . MET B 1 208 ? 289.507 314.175 111.948 1.00 31.00  ? 208 MET B SD  1 
ATOM 3202 C CE  . MET B 1 208 ? 290.045 315.530 112.978 1.00 31.00  ? 208 MET B CE  1 
ATOM 3203 N N   . GLY B 1 209 ? 292.360 309.936 114.692 1.00 20.44  ? 209 GLY B N   1 
ATOM 3204 C CA  . GLY B 1 209 ? 292.804 308.586 114.459 1.00 20.44  ? 209 GLY B CA  1 
ATOM 3205 C C   . GLY B 1 209 ? 293.849 308.231 115.480 1.00 20.44  ? 209 GLY B C   1 
ATOM 3206 O O   . GLY B 1 209 ? 293.798 307.147 116.049 1.00 20.44  ? 209 GLY B O   1 
ATOM 3207 N N   . LEU B 1 210 ? 294.770 309.150 115.766 1.00 17.25  ? 210 LEU B N   1 
ATOM 3208 C CA  . LEU B 1 210 ? 295.569 308.997 116.973 1.00 17.25  ? 210 LEU B CA  1 
ATOM 3209 C C   . LEU B 1 210 ? 294.709 309.146 118.220 1.00 17.25  ? 210 LEU B C   1 
ATOM 3210 O O   . LEU B 1 210 ? 294.915 308.424 119.200 1.00 17.25  ? 210 LEU B O   1 
ATOM 3211 C CB  . LEU B 1 210 ? 296.714 310.003 116.970 1.00 17.25  ? 210 LEU B CB  1 
ATOM 3212 C CG  . LEU B 1 210 ? 297.589 310.108 118.216 1.00 17.25  ? 210 LEU B CG  1 
ATOM 3213 C CD1 . LEU B 1 210 ? 298.194 308.777 118.576 1.00 17.25  ? 210 LEU B CD1 1 
ATOM 3214 C CD2 . LEU B 1 210 ? 298.674 311.133 117.990 1.00 17.25  ? 210 LEU B CD2 1 
ATOM 3215 N N   . LYS B 1 211 ? 293.714 310.033 118.186 1.00 15.08  ? 211 LYS B N   1 
ATOM 3216 C CA  . LYS B 1 211 ? 292.761 310.125 119.286 1.00 15.08  ? 211 LYS B CA  1 
ATOM 3217 C C   . LYS B 1 211 ? 291.876 308.895 119.355 1.00 15.08  ? 211 LYS B C   1 
ATOM 3218 O O   . LYS B 1 211 ? 291.539 308.426 120.449 1.00 15.08  ? 211 LYS B O   1 
ATOM 3219 C CB  . LYS B 1 211 ? 291.903 311.372 119.132 1.00 15.08  ? 211 LYS B CB  1 
ATOM 3220 C CG  . LYS B 1 211 ? 292.541 312.615 119.677 1.00 15.08  ? 211 LYS B CG  1 
ATOM 3221 C CD  . LYS B 1 211 ? 291.970 313.844 119.036 1.00 15.08  ? 211 LYS B CD  1 
ATOM 3222 C CE  . LYS B 1 211 ? 292.648 314.097 117.718 1.00 15.08  ? 211 LYS B CE  1 
ATOM 3223 N NZ  . LYS B 1 211 ? 294.118 314.198 117.906 1.00 15.08  ? 211 LYS B NZ  1 
ATOM 3224 N N   . ILE B 1 212 ? 291.500 308.356 118.196 1.00 11.23  ? 212 ILE B N   1 
ATOM 3225 C CA  . ILE B 1 212 ? 290.717 307.128 118.146 1.00 11.23  ? 212 ILE B CA  1 
ATOM 3226 C C   . ILE B 1 212 ? 291.528 305.968 118.699 1.00 11.23  ? 212 ILE B C   1 
ATOM 3227 O O   . ILE B 1 212 ? 291.006 305.132 119.435 1.00 11.23  ? 212 ILE B O   1 
ATOM 3228 C CB  . ILE B 1 212 ? 290.238 306.874 116.706 1.00 11.23  ? 212 ILE B CB  1 
ATOM 3229 C CG1 . ILE B 1 212 ? 289.192 307.906 116.305 1.00 11.23  ? 212 ILE B CG1 1 
ATOM 3230 C CG2 . ILE B 1 212 ? 289.615 305.527 116.557 1.00 11.23  ? 212 ILE B CG2 1 
ATOM 3231 C CD1 . ILE B 1 212 ? 287.953 307.878 117.157 1.00 11.23  ? 212 ILE B CD1 1 
ATOM 3232 N N   . ARG B 1 213 ? 292.828 305.940 118.414 1.00 10.62  ? 213 ARG B N   1 
ATOM 3233 C CA  . ARG B 1 213 ? 293.693 304.889 118.929 1.00 10.62  ? 213 ARG B CA  1 
ATOM 3234 C C   . ARG B 1 213 ? 293.895 305.002 120.429 1.00 10.62  ? 213 ARG B C   1 
ATOM 3235 O O   . ARG B 1 213 ? 293.934 303.982 121.116 1.00 10.62  ? 213 ARG B O   1 
ATOM 3236 C CB  . ARG B 1 213 ? 295.034 304.924 118.224 1.00 10.62  ? 213 ARG B CB  1 
ATOM 3237 C CG  . ARG B 1 213 ? 295.026 304.236 116.924 1.00 10.62  ? 213 ARG B CG  1 
ATOM 3238 C CD  . ARG B 1 213 ? 296.124 304.749 116.081 1.00 10.62  ? 213 ARG B CD  1 
ATOM 3239 N NE  . ARG B 1 213 ? 297.408 304.412 116.650 1.00 10.62  ? 213 ARG B NE  1 
ATOM 3240 C CZ  . ARG B 1 213 ? 298.560 304.714 116.081 1.00 10.62  ? 213 ARG B CZ  1 
ATOM 3241 N NH1 . ARG B 1 213 ? 298.574 305.371 114.937 1.00 10.62  ? 213 ARG B NH1 1 
ATOM 3242 N NH2 . ARG B 1 213 ? 299.696 304.367 116.659 1.00 10.62  ? 213 ARG B NH2 1 
ATOM 3243 N N   . GLN B 1 214 ? 294.018 306.223 120.956 1.00 7.90   ? 214 GLN B N   1 
ATOM 3244 C CA  . GLN B 1 214 ? 294.119 306.389 122.404 1.00 7.90   ? 214 GLN B CA  1 
ATOM 3245 C C   . GLN B 1 214 ? 292.839 305.960 123.096 1.00 7.90   ? 214 GLN B C   1 
ATOM 3246 O O   . GLN B 1 214 ? 292.880 305.276 124.124 1.00 7.90   ? 214 GLN B O   1 
ATOM 3247 C CB  . GLN B 1 214 ? 294.423 307.836 122.762 1.00 7.90   ? 214 GLN B CB  1 
ATOM 3248 C CG  . GLN B 1 214 ? 295.755 308.331 122.316 1.00 7.90   ? 214 GLN B CG  1 
ATOM 3249 C CD  . GLN B 1 214 ? 296.036 309.718 122.805 1.00 7.90   ? 214 GLN B CD  1 
ATOM 3250 O OE1 . GLN B 1 214 ? 295.613 310.095 123.891 1.00 7.90   ? 214 GLN B OE1 1 
ATOM 3251 N NE2 . GLN B 1 214 ? 296.751 310.495 122.006 1.00 7.90   ? 214 GLN B NE2 1 
ATOM 3252 N N   . LEU B 1 215 ? 291.697 306.332 122.524 1.00 7.38   ? 215 LEU B N   1 
ATOM 3253 C CA  . LEU B 1 215 ? 290.409 305.973 123.094 1.00 7.38   ? 215 LEU B CA  1 
ATOM 3254 C C   . LEU B 1 215 ? 290.177 304.471 123.042 1.00 7.38   ? 215 LEU B C   1 
ATOM 3255 O O   . LEU B 1 215 ? 289.765 303.861 124.038 1.00 7.38   ? 215 LEU B O   1 
ATOM 3256 C CB  . LEU B 1 215 ? 289.328 306.717 122.330 1.00 7.38   ? 215 LEU B CB  1 
ATOM 3257 C CG  . LEU B 1 215 ? 287.947 306.867 122.917 1.00 7.38   ? 215 LEU B CG  1 
ATOM 3258 C CD1 . LEU B 1 215 ? 288.039 307.447 124.299 1.00 7.38   ? 215 LEU B CD1 1 
ATOM 3259 C CD2 . LEU B 1 215 ? 287.209 307.785 122.011 1.00 7.38   ? 215 LEU B CD2 1 
ATOM 3260 N N   . LEU B 1 216 ? 290.481 303.859 121.899 1.00 7.30   ? 216 LEU B N   1 
ATOM 3261 C CA  . LEU B 1 216 ? 290.282 302.433 121.714 1.00 7.30   ? 216 LEU B CA  1 
ATOM 3262 C C   . LEU B 1 216 ? 291.213 301.632 122.599 1.00 7.30   ? 216 LEU B C   1 
ATOM 3263 O O   . LEU B 1 216 ? 290.784 300.650 123.216 1.00 7.30   ? 216 LEU B O   1 
ATOM 3264 C CB  . LEU B 1 216 ? 290.501 302.070 120.253 1.00 7.30   ? 216 LEU B CB  1 
ATOM 3265 C CG  . LEU B 1 216 ? 289.360 302.320 119.283 1.00 7.30   ? 216 LEU B CG  1 
ATOM 3266 C CD1 . LEU B 1 216 ? 289.843 302.093 117.895 1.00 7.30   ? 216 LEU B CD1 1 
ATOM 3267 C CD2 . LEU B 1 216 ? 288.244 301.394 119.583 1.00 7.30   ? 216 LEU B CD2 1 
ATOM 3268 N N   . TRP B 1 217 ? 292.481 302.049 122.684 1.00 7.93   ? 217 TRP B N   1 
ATOM 3269 C CA  . TRP B 1 217 ? 293.435 301.396 123.562 1.00 7.93   ? 217 TRP B CA  1 
ATOM 3270 C C   . TRP B 1 217 ? 292.978 301.467 125.004 1.00 7.93   ? 217 TRP B C   1 
ATOM 3271 O O   . TRP B 1 217 ? 292.981 300.453 125.705 1.00 7.93   ? 217 TRP B O   1 
ATOM 3272 C CB  . TRP B 1 217 ? 294.821 302.029 123.420 1.00 7.93   ? 217 TRP B CB  1 
ATOM 3273 C CG  . TRP B 1 217 ? 295.807 301.350 124.287 1.00 7.93   ? 217 TRP B CG  1 
ATOM 3274 C CD1 . TRP B 1 217 ? 296.522 300.251 123.980 1.00 7.93   ? 217 TRP B CD1 1 
ATOM 3275 C CD2 . TRP B 1 217 ? 296.154 301.690 125.635 1.00 7.93   ? 217 TRP B CD2 1 
ATOM 3276 N NE1 . TRP B 1 217 ? 297.296 299.878 125.041 1.00 7.93   ? 217 TRP B NE1 1 
ATOM 3277 C CE2 . TRP B 1 217 ? 297.085 300.749 126.071 1.00 7.93   ? 217 TRP B CE2 1 
ATOM 3278 C CE3 . TRP B 1 217 ? 295.764 302.704 126.513 1.00 7.93   ? 217 TRP B CE3 1 
ATOM 3279 C CZ2 . TRP B 1 217 ? 297.629 300.785 127.338 1.00 7.93   ? 217 TRP B CZ2 1 
ATOM 3280 C CZ3 . TRP B 1 217 ? 296.293 302.729 127.769 1.00 7.93   ? 217 TRP B CZ3 1 
ATOM 3281 C CH2 . TRP B 1 217 ? 297.218 301.783 128.171 1.00 7.93   ? 217 TRP B CH2 1 
ATOM 3282 N N   . PHE B 1 218 ? 292.560 302.656 125.454 1.00 6.54   ? 218 PHE B N   1 
ATOM 3283 C CA  . PHE B 1 218 ? 292.199 302.845 126.851 1.00 6.54   ? 218 PHE B CA  1 
ATOM 3284 C C   . PHE B 1 218 ? 290.990 302.016 127.226 1.00 6.54   ? 218 PHE B C   1 
ATOM 3285 O O   . PHE B 1 218 ? 290.963 301.397 128.291 1.00 6.54   ? 218 PHE B O   1 
ATOM 3286 C CB  . PHE B 1 218 ? 291.940 304.321 127.131 1.00 6.54   ? 218 PHE B CB  1 
ATOM 3287 C CG  . PHE B 1 218 ? 291.535 304.597 128.539 1.00 6.54   ? 218 PHE B CG  1 
ATOM 3288 C CD1 . PHE B 1 218 ? 292.431 304.453 129.569 1.00 6.54   ? 218 PHE B CD1 1 
ATOM 3289 C CD2 . PHE B 1 218 ? 290.258 304.999 128.834 1.00 6.54   ? 218 PHE B CD2 1 
ATOM 3290 C CE1 . PHE B 1 218 ? 292.052 304.696 130.862 1.00 6.54   ? 218 PHE B CE1 1 
ATOM 3291 C CE2 . PHE B 1 218 ? 289.878 305.237 130.118 1.00 6.54   ? 218 PHE B CE2 1 
ATOM 3292 C CZ  . PHE B 1 218 ? 290.774 305.086 131.132 1.00 6.54   ? 218 PHE B CZ  1 
ATOM 3293 N N   . HIS B 1 219 ? 290.031 301.894 126.316 1.00 6.97   ? 219 HIS B N   1 
ATOM 3294 C CA  . HIS B 1 219 ? 288.811 301.189 126.681 1.00 6.97   ? 219 HIS B CA  1 
ATOM 3295 C C   . HIS B 1 219 ? 288.956 299.678 126.576 1.00 6.97   ? 219 HIS B C   1 
ATOM 3296 O O   . HIS B 1 219 ? 288.535 298.960 127.493 1.00 6.97   ? 219 HIS B O   1 
ATOM 3297 C CB  . HIS B 1 219 ? 287.666 301.721 125.847 1.00 6.97   ? 219 HIS B CB  1 
ATOM 3298 C CG  . HIS B 1 219 ? 287.218 303.069 126.296 1.00 6.97   ? 219 HIS B CG  1 
ATOM 3299 N ND1 . HIS B 1 219 ? 286.782 303.305 127.578 1.00 6.97   ? 219 HIS B ND1 1 
ATOM 3300 C CD2 . HIS B 1 219 ? 287.183 304.259 125.658 1.00 6.97   ? 219 HIS B CD2 1 
ATOM 3301 C CE1 . HIS B 1 219 ? 286.487 304.581 127.707 1.00 6.97   ? 219 HIS B CE1 1 
ATOM 3302 N NE2 . HIS B 1 219 ? 286.708 305.180 126.553 1.00 6.97   ? 219 HIS B NE2 1 
ATOM 3303 N N   . ILE B 1 220 ? 289.600 299.162 125.521 1.00 7.03   ? 220 ILE B N   1 
ATOM 3304 C CA  . ILE B 1 220 ? 289.790 297.718 125.487 1.00 7.03   ? 220 ILE B CA  1 
ATOM 3305 C C   . ILE B 1 220 ? 290.836 297.267 126.500 1.00 7.03   ? 220 ILE B C   1 
ATOM 3306 O O   . ILE B 1 220 ? 290.786 296.122 126.953 1.00 7.03   ? 220 ILE B O   1 
ATOM 3307 C CB  . ILE B 1 220 ? 290.136 297.195 124.078 1.00 7.03   ? 220 ILE B CB  1 
ATOM 3308 C CG1 . ILE B 1 220 ? 291.571 297.476 123.724 1.00 7.03   ? 220 ILE B CG1 1 
ATOM 3309 C CG2 . ILE B 1 220 ? 289.256 297.793 123.026 1.00 7.03   ? 220 ILE B CG2 1 
ATOM 3310 C CD1 . ILE B 1 220 ? 291.963 296.875 122.441 1.00 7.03   ? 220 ILE B CD1 1 
ATOM 3311 N N   . SER B 1 221 ? 291.731 298.154 126.944 1.00 8.98   ? 221 SER B N   1 
ATOM 3312 C CA  . SER B 1 221 ? 292.692 297.784 127.966 1.00 8.98   ? 221 SER B CA  1 
ATOM 3313 C C   . SER B 1 221 ? 292.100 297.871 129.352 1.00 8.98   ? 221 SER B C   1 
ATOM 3314 O O   . SER B 1 221 ? 292.499 297.111 130.230 1.00 8.98   ? 221 SER B O   1 
ATOM 3315 C CB  . SER B 1 221 ? 293.918 298.671 127.868 1.00 8.98   ? 221 SER B CB  1 
ATOM 3316 O OG  . SER B 1 221 ? 294.322 298.784 126.524 1.00 8.98   ? 221 SER B OG  1 
ATOM 3317 N N   . CYS B 1 222 ? 291.156 298.777 129.578 1.00 8.49   ? 222 CYS B N   1 
ATOM 3318 C CA  . CYS B 1 222 ? 290.468 298.790 130.854 1.00 8.49   ? 222 CYS B CA  1 
ATOM 3319 C C   . CYS B 1 222 ? 289.507 297.631 130.973 1.00 8.49   ? 222 CYS B C   1 
ATOM 3320 O O   . CYS B 1 222 ? 289.204 297.200 132.086 1.00 8.49   ? 222 CYS B O   1 
ATOM 3321 C CB  . CYS B 1 222 ? 289.721 300.100 131.027 1.00 8.49   ? 222 CYS B CB  1 
ATOM 3322 S SG  . CYS B 1 222 ? 290.743 301.452 131.583 1.00 8.49   ? 222 CYS B SG  1 
ATOM 3323 N N   . LEU B 1 223 ? 289.011 297.128 129.848 1.00 8.28   ? 223 LEU B N   1 
ATOM 3324 C CA  . LEU B 1 223 ? 288.185 295.932 129.896 1.00 8.28   ? 223 LEU B CA  1 
ATOM 3325 C C   . LEU B 1 223 ? 289.024 294.671 130.062 1.00 8.28   ? 223 LEU B C   1 
ATOM 3326 O O   . LEU B 1 223 ? 288.624 293.755 130.785 1.00 8.28   ? 223 LEU B O   1 
ATOM 3327 C CB  . LEU B 1 223 ? 287.335 295.850 128.634 1.00 8.28   ? 223 LEU B CB  1 
ATOM 3328 C CG  . LEU B 1 223 ? 286.169 296.813 128.548 1.00 8.28   ? 223 LEU B CG  1 
ATOM 3329 C CD1 . LEU B 1 223 ? 285.758 296.988 127.124 1.00 8.28   ? 223 LEU B CD1 1 
ATOM 3330 C CD2 . LEU B 1 223 ? 285.046 296.256 129.354 1.00 8.28   ? 223 LEU B CD2 1 
ATOM 3331 N N   . THR B 1 224 ? 290.190 294.611 129.412 1.00 10.31  ? 224 THR B N   1 
ATOM 3332 C CA  . THR B 1 224 ? 291.025 293.414 129.459 1.00 10.31  ? 224 THR B CA  1 
ATOM 3333 C C   . THR B 1 224 ? 291.683 293.230 130.819 1.00 10.31  ? 224 THR B C   1 
ATOM 3334 O O   . THR B 1 224 ? 291.693 292.126 131.368 1.00 10.31  ? 224 THR B O   1 
ATOM 3335 C CB  . THR B 1 224 ? 292.099 293.486 128.383 1.00 10.31  ? 224 THR B CB  1 
ATOM 3336 O OG1 . THR B 1 224 ? 291.527 293.929 127.155 1.00 10.31  ? 224 THR B OG1 1 
ATOM 3337 C CG2 . THR B 1 224 ? 292.705 292.147 128.171 1.00 10.31  ? 224 THR B CG2 1 
ATOM 3338 N N   . PHE B 1 225 ? 292.246 294.296 131.376 1.00 12.18  ? 225 PHE B N   1 
ATOM 3339 C CA  . PHE B 1 225 ? 293.140 294.201 132.516 1.00 12.18  ? 225 PHE B CA  1 
ATOM 3340 C C   . PHE B 1 225 ? 292.554 294.733 133.809 1.00 12.18  ? 225 PHE B C   1 
ATOM 3341 O O   . PHE B 1 225 ? 293.263 294.774 134.814 1.00 12.18  ? 225 PHE B O   1 
ATOM 3342 C CB  . PHE B 1 225 ? 294.436 294.956 132.221 1.00 12.18  ? 225 PHE B CB  1 
ATOM 3343 C CG  . PHE B 1 225 ? 295.153 294.469 131.013 1.00 12.18  ? 225 PHE B CG  1 
ATOM 3344 C CD1 . PHE B 1 225 ? 295.764 293.240 131.011 1.00 12.18  ? 225 PHE B CD1 1 
ATOM 3345 C CD2 . PHE B 1 225 ? 295.220 295.243 129.881 1.00 12.18  ? 225 PHE B CD2 1 
ATOM 3346 C CE1 . PHE B 1 225 ? 296.418 292.788 129.902 1.00 12.18  ? 225 PHE B CE1 1 
ATOM 3347 C CE2 . PHE B 1 225 ? 295.883 294.796 128.765 1.00 12.18  ? 225 PHE B CE2 1 
ATOM 3348 C CZ  . PHE B 1 225 ? 296.480 293.567 128.778 1.00 12.18  ? 225 PHE B CZ  1 
ATOM 3349 N N   . GLY B 1 226 ? 291.293 295.129 133.827 1.00 15.84  ? 226 GLY B N   1 
ATOM 3350 C CA  . GLY B 1 226 ? 290.773 295.928 134.913 1.00 15.84  ? 226 GLY B CA  1 
ATOM 3351 C C   . GLY B 1 226 ? 291.096 297.391 134.698 1.00 15.84  ? 226 GLY B C   1 
ATOM 3352 O O   . GLY B 1 226 ? 291.810 297.773 133.776 1.00 15.84  ? 226 GLY B O   1 
ATOM 3353 N N   . ARG B 1 227 ? 290.554 298.238 135.564 1.00 23.76  ? 227 ARG B N   1 
ATOM 3354 C CA  . ARG B 1 227 ? 290.742 299.666 135.355 1.00 23.76  ? 227 ARG B CA  1 
ATOM 3355 C C   . ARG B 1 227 ? 291.818 300.266 136.232 1.00 23.76  ? 227 ARG B C   1 
ATOM 3356 O O   . ARG B 1 227 ? 292.573 301.112 135.759 1.00 23.76  ? 227 ARG B O   1 
ATOM 3357 C CB  . ARG B 1 227 ? 289.446 300.432 135.584 1.00 23.76  ? 227 ARG B CB  1 
ATOM 3358 C CG  . ARG B 1 227 ? 289.450 301.782 134.918 1.00 23.76  ? 227 ARG B CG  1 
ATOM 3359 C CD  . ARG B 1 227 ? 288.314 302.613 135.398 1.00 23.76  ? 227 ARG B CD  1 
ATOM 3360 N NE  . ARG B 1 227 ? 288.185 302.502 136.839 1.00 23.76  ? 227 ARG B NE  1 
ATOM 3361 C CZ  . ARG B 1 227 ? 287.024 302.496 137.472 1.00 23.76  ? 227 ARG B CZ  1 
ATOM 3362 N NH1 . ARG B 1 227 ? 285.901 302.601 136.780 1.00 23.76  ? 227 ARG B NH1 1 
ATOM 3363 N NH2 . ARG B 1 227 ? 286.990 302.388 138.791 1.00 23.76  ? 227 ARG B NH2 1 
ATOM 3364 N N   . GLU B 1 228 ? 291.908 299.845 137.495 1.00 23.97  ? 228 GLU B N   1 
ATOM 3365 C CA  . GLU B 1 228 ? 292.971 300.332 138.364 1.00 23.97  ? 228 GLU B CA  1 
ATOM 3366 C C   . GLU B 1 228 ? 294.343 299.913 137.865 1.00 23.97  ? 228 GLU B C   1 
ATOM 3367 O O   . GLU B 1 228 ? 295.318 300.644 138.056 1.00 23.97  ? 228 GLU B O   1 
ATOM 3368 C CB  . GLU B 1 228 ? 292.754 299.832 139.782 1.00 23.97  ? 228 GLU B CB  1 
ATOM 3369 C CG  . GLU B 1 228 ? 291.652 300.559 140.501 1.00 23.97  ? 228 GLU B CG  1 
ATOM 3370 C CD  . GLU B 1 228 ? 290.378 299.752 140.598 1.00 23.97  ? 228 GLU B CD  1 
ATOM 3371 O OE1 . GLU B 1 228 ? 290.412 298.535 140.326 1.00 23.97  ? 228 GLU B OE1 1 
ATOM 3372 O OE2 . GLU B 1 228 ? 289.336 300.337 140.954 1.00 23.97  ? 228 GLU B OE2 1 
ATOM 3373 N N   . THR B 1 229 ? 294.429 298.770 137.191 1.00 15.61  ? 229 THR B N   1 
ATOM 3374 C CA  . THR B 1 229 ? 295.690 298.336 136.611 1.00 15.61  ? 229 THR B CA  1 
ATOM 3375 C C   . THR B 1 229 ? 296.109 299.232 135.455 1.00 15.61  ? 229 THR B C   1 
ATOM 3376 O O   . THR B 1 229 ? 297.298 299.522 135.297 1.00 15.61  ? 229 THR B O   1 
ATOM 3377 C CB  . THR B 1 229 ? 295.566 296.888 136.169 1.00 15.61  ? 229 THR B CB  1 
ATOM 3378 O OG1 . THR B 1 229 ? 295.005 296.131 137.243 1.00 15.61  ? 229 THR B OG1 1 
ATOM 3379 C CG2 . THR B 1 229 ? 296.908 296.311 135.829 1.00 15.61  ? 229 THR B CG2 1 
ATOM 3380 N N   . VAL B 1 230 ? 295.154 299.729 134.670 1.00 10.12  ? 230 VAL B N   1 
ATOM 3381 C CA  . VAL B 1 230 ? 295.527 300.617 133.574 1.00 10.12  ? 230 VAL B CA  1 
ATOM 3382 C C   . VAL B 1 230 ? 295.943 301.976 134.107 1.00 10.12  ? 230 VAL B C   1 
ATOM 3383 O O   . VAL B 1 230 ? 296.870 302.597 133.581 1.00 10.12  ? 230 VAL B O   1 
ATOM 3384 C CB  . VAL B 1 230 ? 294.384 300.723 132.555 1.00 10.12  ? 230 VAL B CB  1 
ATOM 3385 C CG1 . VAL B 1 230 ? 294.772 301.583 131.386 1.00 10.12  ? 230 VAL B CG1 1 
ATOM 3386 C CG2 . VAL B 1 230 ? 294.065 299.377 132.057 1.00 10.12  ? 230 VAL B CG2 1 
ATOM 3387 N N   . LEU B 1 231 ? 295.326 302.432 135.194 1.00 11.08  ? 231 LEU B N   1 
ATOM 3388 C CA  . LEU B 1 231 ? 295.721 303.712 135.768 1.00 11.08  ? 231 LEU B CA  1 
ATOM 3389 C C   . LEU B 1 231 ? 297.099 303.631 136.415 1.00 11.08  ? 231 LEU B C   1 
ATOM 3390 O O   . LEU B 1 231 ? 297.920 304.541 136.244 1.00 11.08  ? 231 LEU B O   1 
ATOM 3391 C CB  . LEU B 1 231 ? 294.669 304.177 136.769 1.00 11.08  ? 231 LEU B CB  1 
ATOM 3392 C CG  . LEU B 1 231 ? 293.254 304.277 136.208 1.00 11.08  ? 231 LEU B CG  1 
ATOM 3393 C CD1 . LEU B 1 231 ? 292.277 304.592 137.301 1.00 11.08  ? 231 LEU B CD1 1 
ATOM 3394 C CD2 . LEU B 1 231 ? 293.178 305.297 135.122 1.00 11.08  ? 231 LEU B CD2 1 
ATOM 3395 N N   . GLU B 1 232 ? 297.380 302.536 137.132 1.00 12.23  ? 232 GLU B N   1 
ATOM 3396 C CA  . GLU B 1 232 ? 298.712 302.328 137.688 1.00 12.23  ? 232 GLU B CA  1 
ATOM 3397 C C   . GLU B 1 232 ? 299.762 302.187 136.597 1.00 12.23  ? 232 GLU B C   1 
ATOM 3398 O O   . GLU B 1 232 ? 300.893 302.669 136.746 1.00 12.23  ? 232 GLU B O   1 
ATOM 3399 C CB  . GLU B 1 232 ? 298.721 301.092 138.566 1.00 12.23  ? 232 GLU B CB  1 
ATOM 3400 C CG  . GLU B 1 232 ? 297.961 301.249 139.840 1.00 12.23  ? 232 GLU B CG  1 
ATOM 3401 C CD  . GLU B 1 232 ? 297.547 299.914 140.421 1.00 12.23  ? 232 GLU B CD  1 
ATOM 3402 O OE1 . GLU B 1 232 ? 298.111 298.885 139.997 1.00 12.23  ? 232 GLU B OE1 1 
ATOM 3403 O OE2 . GLU B 1 232 ? 296.662 299.888 141.298 1.00 12.23  ? 232 GLU B OE2 1 
ATOM 3404 N N   . TYR B 1 233 ? 299.406 301.538 135.491 1.00 13.33  ? 233 TYR B N   1 
ATOM 3405 C CA  . TYR B 1 233 ? 300.331 301.442 134.379 1.00 13.33  ? 233 TYR B CA  1 
ATOM 3406 C C   . TYR B 1 233 ? 300.590 302.801 133.756 1.00 13.33  ? 233 TYR B C   1 
ATOM 3407 O O   . TYR B 1 233 ? 301.706 303.078 133.321 1.00 13.33  ? 233 TYR B O   1 
ATOM 3408 C CB  . TYR B 1 233 ? 299.806 300.479 133.328 1.00 13.33  ? 233 TYR B CB  1 
ATOM 3409 C CG  . TYR B 1 233 ? 300.689 300.419 132.121 1.00 13.33  ? 233 TYR B CG  1 
ATOM 3410 C CD1 . TYR B 1 233 ? 301.910 299.807 132.182 1.00 13.33  ? 233 TYR B CD1 1 
ATOM 3411 C CD2 . TYR B 1 233 ? 300.307 301.000 130.928 1.00 13.33  ? 233 TYR B CD2 1 
ATOM 3412 C CE1 . TYR B 1 233 ? 302.718 299.758 131.099 1.00 13.33  ? 233 TYR B CE1 1 
ATOM 3413 C CE2 . TYR B 1 233 ? 301.118 300.958 129.839 1.00 13.33  ? 233 TYR B CE2 1 
ATOM 3414 C CZ  . TYR B 1 233 ? 302.325 300.330 129.936 1.00 13.33  ? 233 TYR B CZ  1 
ATOM 3415 O OH  . TYR B 1 233 ? 303.147 300.273 128.848 1.00 13.33  ? 233 TYR B OH  1 
ATOM 3416 N N   . LEU B 1 234 ? 299.590 303.668 133.706 1.00 15.77  ? 234 LEU B N   1 
ATOM 3417 C CA  . LEU B 1 234 ? 299.831 304.966 133.097 1.00 15.77  ? 234 LEU B CA  1 
ATOM 3418 C C   . LEU B 1 234 ? 300.665 305.857 133.993 1.00 15.77  ? 234 LEU B C   1 
ATOM 3419 O O   . LEU B 1 234 ? 301.483 306.630 133.487 1.00 15.77  ? 234 LEU B O   1 
ATOM 3420 C CB  . LEU B 1 234 ? 298.518 305.655 132.762 1.00 15.77  ? 234 LEU B CB  1 
ATOM 3421 C CG  . LEU B 1 234 ? 297.687 305.078 131.631 1.00 15.77  ? 234 LEU B CG  1 
ATOM 3422 C CD1 . LEU B 1 234 ? 296.264 305.415 131.903 1.00 15.77  ? 234 LEU B CD1 1 
ATOM 3423 C CD2 . LEU B 1 234 ? 298.115 305.655 130.344 1.00 15.77  ? 234 LEU B CD2 1 
ATOM 3424 N N   . VAL B 1 235 ? 300.505 305.724 135.312 1.00 6.08   ? 235 VAL B N   1 
ATOM 3425 C CA  . VAL B 1 235 ? 301.374 306.429 136.256 1.00 6.08   ? 235 VAL B CA  1 
ATOM 3426 C C   . VAL B 1 235 ? 302.826 305.999 136.071 1.00 6.08   ? 235 VAL B C   1 
ATOM 3427 O O   . VAL B 1 235 ? 303.716 306.830 135.841 1.00 6.08   ? 235 VAL B O   1 
ATOM 3428 C CB  . VAL B 1 235 ? 300.904 306.181 137.698 1.00 6.08   ? 235 VAL B CB  1 
ATOM 3429 C CG1 . VAL B 1 235 ? 301.900 306.720 138.663 1.00 6.08   ? 235 VAL B CG1 1 
ATOM 3430 C CG2 . VAL B 1 235 ? 299.571 306.806 137.939 1.00 6.08   ? 235 VAL B CG2 1 
ATOM 3431 N N   . SER B 1 236 ? 303.078 304.688 136.124 1.00 15.13  ? 236 SER B N   1 
ATOM 3432 C CA  . SER B 1 236 ? 304.449 304.195 136.045 1.00 15.13  ? 236 SER B CA  1 
ATOM 3433 C C   . SER B 1 236 ? 305.056 304.367 134.659 1.00 15.13  ? 236 SER B C   1 
ATOM 3434 O O   . SER B 1 236 ? 306.265 304.590 134.545 1.00 15.13  ? 236 SER B O   1 
ATOM 3435 C CB  . SER B 1 236 ? 304.482 302.743 136.465 1.00 15.13  ? 236 SER B CB  1 
ATOM 3436 O OG  . SER B 1 236 ? 303.675 302.568 137.613 1.00 15.13  ? 236 SER B OG  1 
ATOM 3437 N N   . PHE B 1 237 ? 304.253 304.300 133.600 1.00 28.56  ? 237 PHE B N   1 
ATOM 3438 C CA  . PHE B 1 237 ? 304.774 304.626 132.284 1.00 28.56  ? 237 PHE B CA  1 
ATOM 3439 C C   . PHE B 1 237 ? 305.075 306.107 132.160 1.00 28.56  ? 237 PHE B C   1 
ATOM 3440 O O   . PHE B 1 237 ? 305.982 306.478 131.417 1.00 28.56  ? 237 PHE B O   1 
ATOM 3441 C CB  . PHE B 1 237 ? 303.805 304.213 131.184 1.00 28.56  ? 237 PHE B CB  1 
ATOM 3442 C CG  . PHE B 1 237 ? 304.423 304.194 129.810 1.00 28.56  ? 237 PHE B CG  1 
ATOM 3443 C CD1 . PHE B 1 237 ? 305.016 303.061 129.330 1.00 28.56  ? 237 PHE B CD1 1 
ATOM 3444 C CD2 . PHE B 1 237 ? 304.404 305.305 129.006 1.00 28.56  ? 237 PHE B CD2 1 
ATOM 3445 C CE1 . PHE B 1 237 ? 305.576 303.048 128.093 1.00 28.56  ? 237 PHE B CE1 1 
ATOM 3446 C CE2 . PHE B 1 237 ? 304.966 305.289 127.781 1.00 28.56  ? 237 PHE B CE2 1 
ATOM 3447 C CZ  . PHE B 1 237 ? 305.547 304.165 127.321 1.00 28.56  ? 237 PHE B CZ  1 
ATOM 3448 N N   . GLY B 1 238 ? 304.338 306.966 132.858 1.00 20.14  ? 238 GLY B N   1 
ATOM 3449 C CA  . GLY B 1 238 ? 304.687 308.371 132.842 1.00 20.14  ? 238 GLY B CA  1 
ATOM 3450 C C   . GLY B 1 238 ? 306.020 308.627 133.508 1.00 20.14  ? 238 GLY B C   1 
ATOM 3451 O O   . GLY B 1 238 ? 306.824 309.422 133.017 1.00 20.14  ? 238 GLY B O   1 
ATOM 3452 N N   . VAL B 1 239 ? 306.283 307.921 134.610 1.00 28.56  ? 239 VAL B N   1 
ATOM 3453 C CA  . VAL B 1 239 ? 307.577 308.032 135.284 1.00 28.56  ? 239 VAL B CA  1 
ATOM 3454 C C   . VAL B 1 239 ? 308.696 307.523 134.389 1.00 28.56  ? 239 VAL B C   1 
ATOM 3455 O O   . VAL B 1 239 ? 309.783 308.105 134.336 1.00 28.56  ? 239 VAL B O   1 
ATOM 3456 C CB  . VAL B 1 239 ? 307.543 307.285 136.625 1.00 28.56  ? 239 VAL B CB  1 
ATOM 3457 C CG1 . VAL B 1 239 ? 308.796 307.502 137.376 1.00 28.56  ? 239 VAL B CG1 1 
ATOM 3458 C CG2 . VAL B 1 239 ? 306.428 307.784 137.429 1.00 28.56  ? 239 VAL B CG2 1 
ATOM 3459 N N   . TRP B 1 240 ? 308.435 306.453 133.641 1.00 28.56  ? 240 TRP B N   1 
ATOM 3460 C CA  . TRP B 1 240 ? 309.453 305.907 132.753 1.00 28.56  ? 240 TRP B CA  1 
ATOM 3461 C C   . TRP B 1 240 ? 309.731 306.832 131.573 1.00 28.56  ? 240 TRP B C   1 
ATOM 3462 O O   . TRP B 1 240 ? 310.887 307.073 131.225 1.00 28.56  ? 240 TRP B O   1 
ATOM 3463 C CB  . TRP B 1 240 ? 309.029 304.522 132.273 1.00 28.56  ? 240 TRP B CB  1 
ATOM 3464 C CG  . TRP B 1 240 ? 310.078 303.859 131.477 1.00 28.56  ? 240 TRP B CG  1 
ATOM 3465 C CD1 . TRP B 1 240 ? 311.108 303.116 131.944 1.00 28.56  ? 240 TRP B CD1 1 
ATOM 3466 C CD2 . TRP B 1 240 ? 310.220 303.899 130.060 1.00 28.56  ? 240 TRP B CD2 1 
ATOM 3467 N NE1 . TRP B 1 240 ? 311.887 302.690 130.906 1.00 28.56  ? 240 TRP B NE1 1 
ATOM 3468 C CE2 . TRP B 1 240 ? 311.359 303.164 129.737 1.00 28.56  ? 240 TRP B CE2 1 
ATOM 3469 C CE3 . TRP B 1 240 ? 309.493 304.500 129.032 1.00 28.56  ? 240 TRP B CE3 1 
ATOM 3470 C CZ2 . TRP B 1 240 ? 311.783 303.003 128.433 1.00 28.56  ? 240 TRP B CZ2 1 
ATOM 3471 C CZ3 . TRP B 1 240 ? 309.915 304.340 127.748 1.00 28.56  ? 240 TRP B CZ3 1 
ATOM 3472 C CH2 . TRP B 1 240 ? 311.046 303.594 127.455 1.00 28.56  ? 240 TRP B CH2 1 
ATOM 3473 N N   . ILE B 1 241 ? 308.691 307.373 130.947 1.00 28.56  ? 241 ILE B N   1 
ATOM 3474 C CA  . ILE B 1 241 ? 308.900 308.202 129.764 1.00 28.56  ? 241 ILE B CA  1 
ATOM 3475 C C   . ILE B 1 241 ? 309.380 309.606 130.121 1.00 28.56  ? 241 ILE B C   1 
ATOM 3476 O O   . ILE B 1 241 ? 309.971 310.281 129.273 1.00 28.56  ? 241 ILE B O   1 
ATOM 3477 C CB  . ILE B 1 241 ? 307.611 308.229 128.919 1.00 28.56  ? 241 ILE B CB  1 
ATOM 3478 C CG1 . ILE B 1 241 ? 307.869 308.680 127.476 1.00 28.56  ? 241 ILE B CG1 1 
ATOM 3479 C CG2 . ILE B 1 241 ? 306.572 309.106 129.545 1.00 28.56  ? 241 ILE B CG2 1 
ATOM 3480 C CD1 . ILE B 1 241 ? 308.716 307.744 126.669 1.00 28.56  ? 241 ILE B CD1 1 
ATOM 3481 N N   . ARG B 1 242 ? 309.187 310.058 131.364 1.00 22.18  ? 242 ARG B N   1 
ATOM 3482 C CA  . ARG B 1 242 ? 309.657 311.386 131.741 1.00 22.18  ? 242 ARG B CA  1 
ATOM 3483 C C   . ARG B 1 242 ? 311.137 311.401 132.077 1.00 22.18  ? 242 ARG B C   1 
ATOM 3484 O O   . ARG B 1 242 ? 311.770 312.454 131.995 1.00 22.18  ? 242 ARG B O   1 
ATOM 3485 C CB  . ARG B 1 242 ? 308.862 311.905 132.928 1.00 22.18  ? 242 ARG B CB  1 
ATOM 3486 C CG  . ARG B 1 242 ? 307.786 312.870 132.559 1.00 22.18  ? 242 ARG B CG  1 
ATOM 3487 C CD  . ARG B 1 242 ? 307.106 313.364 133.789 1.00 22.18  ? 242 ARG B CD  1 
ATOM 3488 N NE  . ARG B 1 242 ? 306.090 312.436 134.242 1.00 22.18  ? 242 ARG B NE  1 
ATOM 3489 C CZ  . ARG B 1 242 ? 306.106 311.861 135.430 1.00 22.18  ? 242 ARG B CZ  1 
ATOM 3490 N NH1 . ARG B 1 242 ? 305.145 311.022 135.775 1.00 22.18  ? 242 ARG B NH1 1 
ATOM 3491 N NH2 . ARG B 1 242 ? 307.091 312.118 136.269 1.00 22.18  ? 242 ARG B NH2 1 
ATOM 3492 N N   . THR B 1 243 ? 311.685 310.260 132.478 1.00 13.72  ? 243 THR B N   1 
ATOM 3493 C CA  . THR B 1 243 ? 313.101 310.129 132.767 1.00 13.72  ? 243 THR B CA  1 
ATOM 3494 C C   . THR B 1 243 ? 313.904 310.289 131.482 1.00 13.72  ? 243 THR B C   1 
ATOM 3495 O O   . THR B 1 243 ? 313.433 309.916 130.409 1.00 13.72  ? 243 THR B O   1 
ATOM 3496 C CB  . THR B 1 243 ? 313.373 308.764 133.376 1.00 13.72  ? 243 THR B CB  1 
ATOM 3497 O OG1 . THR B 1 243 ? 312.321 308.439 134.283 1.00 13.72  ? 243 THR B OG1 1 
ATOM 3498 C CG2 . THR B 1 243 ? 314.635 308.763 134.150 1.00 13.72  ? 243 THR B CG2 1 
ATOM 3499 N N   . PRO B 1 244 ? 315.090 310.887 131.550 1.00 12.45  ? 244 PRO B N   1 
ATOM 3500 C CA  . PRO B 1 244 ? 315.969 310.927 130.385 1.00 12.45  ? 244 PRO B CA  1 
ATOM 3501 C C   . PRO B 1 244 ? 316.392 309.530 129.973 1.00 12.45  ? 244 PRO B C   1 
ATOM 3502 O O   . PRO B 1 244 ? 316.306 308.594 130.779 1.00 12.45  ? 244 PRO B O   1 
ATOM 3503 C CB  . PRO B 1 244 ? 317.162 311.749 130.886 1.00 12.45  ? 244 PRO B CB  1 
ATOM 3504 C CG  . PRO B 1 244 ? 316.577 312.641 131.859 1.00 12.45  ? 244 PRO B CG  1 
ATOM 3505 C CD  . PRO B 1 244 ? 315.487 311.894 132.542 1.00 12.45  ? 244 PRO B CD  1 
ATOM 3506 N N   . PRO B 1 245 ? 316.827 309.342 128.725 1.00 15.98  ? 245 PRO B N   1 
ATOM 3507 C CA  . PRO B 1 245 ? 317.225 307.997 128.285 1.00 15.98  ? 245 PRO B CA  1 
ATOM 3508 C C   . PRO B 1 245 ? 318.414 307.430 129.026 1.00 15.98  ? 245 PRO B C   1 
ATOM 3509 O O   . PRO B 1 245 ? 318.551 306.207 129.108 1.00 15.98  ? 245 PRO B O   1 
ATOM 3510 C CB  . PRO B 1 245 ? 317.546 308.203 126.803 1.00 15.98  ? 245 PRO B CB  1 
ATOM 3511 C CG  . PRO B 1 245 ? 316.780 309.387 126.415 1.00 15.98  ? 245 PRO B CG  1 
ATOM 3512 C CD  . PRO B 1 245 ? 316.769 310.282 127.595 1.00 15.98  ? 245 PRO B CD  1 
ATOM 3513 N N   . ALA B 1 246 ? 319.269 308.276 129.589 1.00 13.08  ? 246 ALA B N   1 
ATOM 3514 C CA  . ALA B 1 246 ? 320.459 307.781 130.255 1.00 13.08  ? 246 ALA B CA  1 
ATOM 3515 C C   . ALA B 1 246 ? 320.164 307.176 131.617 1.00 13.08  ? 246 ALA B C   1 
ATOM 3516 O O   . ALA B 1 246 ? 320.916 306.308 132.061 1.00 13.08  ? 246 ALA B O   1 
ATOM 3517 C CB  . ALA B 1 246 ? 321.477 308.907 130.394 1.00 13.08  ? 246 ALA B CB  1 
ATOM 3518 N N   . TYR B 1 247 ? 319.090 307.586 132.282 1.00 10.94  ? 247 TYR B N   1 
ATOM 3519 C CA  . TYR B 1 247 ? 318.882 307.234 133.680 1.00 10.94  ? 247 TYR B CA  1 
ATOM 3520 C C   . TYR B 1 247 ? 317.625 306.410 133.901 1.00 10.94  ? 247 TYR B C   1 
ATOM 3521 O O   . TYR B 1 247 ? 317.012 306.499 134.962 1.00 10.94  ? 247 TYR B O   1 
ATOM 3522 C CB  . TYR B 1 247 ? 318.824 308.481 134.554 1.00 10.94  ? 247 TYR B CB  1 
ATOM 3523 C CG  . TYR B 1 247 ? 319.854 309.524 134.229 1.00 10.94  ? 247 TYR B CG  1 
ATOM 3524 C CD1 . TYR B 1 247 ? 321.183 309.323 134.521 1.00 10.94  ? 247 TYR B CD1 1 
ATOM 3525 C CD2 . TYR B 1 247 ? 319.486 310.718 133.649 1.00 10.94  ? 247 TYR B CD2 1 
ATOM 3526 C CE1 . TYR B 1 247 ? 322.116 310.275 134.230 1.00 10.94  ? 247 TYR B CE1 1 
ATOM 3527 C CE2 . TYR B 1 247 ? 320.408 311.675 133.355 1.00 10.94  ? 247 TYR B CE2 1 
ATOM 3528 C CZ  . TYR B 1 247 ? 321.719 311.453 133.650 1.00 10.94  ? 247 TYR B CZ  1 
ATOM 3529 O OH  . TYR B 1 247 ? 322.641 312.422 133.351 1.00 10.94  ? 247 TYR B OH  1 
ATOM 3530 N N   . ARG B 1 248 ? 317.230 305.604 132.930 1.00 22.77  ? 248 ARG B N   1 
ATOM 3531 C CA  . ARG B 1 248 ? 316.072 304.734 133.055 1.00 22.77  ? 248 ARG B CA  1 
ATOM 3532 C C   . ARG B 1 248 ? 316.438 303.348 132.564 1.00 22.77  ? 248 ARG B C   1 
ATOM 3533 O O   . ARG B 1 248 ? 317.408 303.190 131.817 1.00 22.77  ? 248 ARG B O   1 
ATOM 3534 C CB  . ARG B 1 248 ? 314.874 305.276 132.262 1.00 22.77  ? 248 ARG B CB  1 
ATOM 3535 C CG  . ARG B 1 248 ? 315.090 305.477 130.781 1.00 22.77  ? 248 ARG B CG  1 
ATOM 3536 C CD  . ARG B 1 248 ? 313.743 305.725 130.137 1.00 22.77  ? 248 ARG B CD  1 
ATOM 3537 N NE  . ARG B 1 248 ? 313.786 305.864 128.690 1.00 22.77  ? 248 ARG B NE  1 
ATOM 3538 C CZ  . ARG B 1 248 ? 313.171 306.831 128.023 1.00 22.77  ? 248 ARG B CZ  1 
ATOM 3539 N NH1 . ARG B 1 248 ? 312.481 307.745 128.675 1.00 22.77  ? 248 ARG B NH1 1 
ATOM 3540 N NH2 . ARG B 1 248 ? 313.254 306.891 126.707 1.00 22.77  ? 248 ARG B NH2 1 
ATOM 3541 N N   . PRO B 1 249 ? 315.728 302.316 133.022 1.00 13.59  ? 249 PRO B N   1 
ATOM 3542 C CA  . PRO B 1 249 ? 315.872 300.990 132.443 1.00 13.59  ? 249 PRO B CA  1 
ATOM 3543 C C   . PRO B 1 249 ? 315.567 301.013 130.960 1.00 13.59  ? 249 PRO B C   1 
ATOM 3544 O O   . PRO B 1 249 ? 314.652 301.720 130.524 1.00 13.59  ? 249 PRO B O   1 
ATOM 3545 C CB  . PRO B 1 249 ? 314.831 300.170 133.207 1.00 13.59  ? 249 PRO B CB  1 
ATOM 3546 C CG  . PRO B 1 249 ? 314.766 300.790 134.494 1.00 13.59  ? 249 PRO B CG  1 
ATOM 3547 C CD  . PRO B 1 249 ? 314.977 302.255 134.283 1.00 13.59  ? 249 PRO B CD  1 
ATOM 3548 N N   . PRO B 1 250 ? 316.304 300.247 130.152 1.00 13.48  ? 250 PRO B N   1 
ATOM 3549 C CA  . PRO B 1 250 ? 316.305 300.484 128.706 1.00 13.48  ? 250 PRO B CA  1 
ATOM 3550 C C   . PRO B 1 250 ? 315.036 300.060 127.990 1.00 13.48  ? 250 PRO B C   1 
ATOM 3551 O O   . PRO B 1 250 ? 314.923 300.305 126.787 1.00 13.48  ? 250 PRO B O   1 
ATOM 3552 C CB  . PRO B 1 250 ? 317.495 299.655 128.232 1.00 13.48  ? 250 PRO B CB  1 
ATOM 3553 C CG  . PRO B 1 250 ? 317.557 298.554 129.188 1.00 13.48  ? 250 PRO B CG  1 
ATOM 3554 C CD  . PRO B 1 250 ? 317.106 299.069 130.509 1.00 13.48  ? 250 PRO B CD  1 
ATOM 3555 N N   . ASN B 1 251 ? 314.071 299.460 128.676 1.00 14.86  ? 251 ASN B N   1 
ATOM 3556 C CA  . ASN B 1 251 ? 312.863 298.995 128.025 1.00 14.86  ? 251 ASN B CA  1 
ATOM 3557 C C   . ASN B 1 251 ? 311.636 299.265 128.891 1.00 14.86  ? 251 ASN B C   1 
ATOM 3558 O O   . ASN B 1 251 ? 311.681 299.140 130.118 1.00 14.86  ? 251 ASN B O   1 
ATOM 3559 C CB  . ASN B 1 251 ? 313.016 297.518 127.646 1.00 14.86  ? 251 ASN B CB  1 
ATOM 3560 C CG  . ASN B 1 251 ? 313.497 296.652 128.792 1.00 14.86  ? 251 ASN B CG  1 
ATOM 3561 O OD1 . ASN B 1 251 ? 313.557 297.072 129.943 1.00 14.86  ? 251 ASN B OD1 1 
ATOM 3562 N ND2 . ASN B 1 251 ? 313.890 295.431 128.459 1.00 14.86  ? 251 ASN B ND2 1 
ATOM 3563 N N   . ALA B 1 252 ? 310.543 299.646 128.223 1.00 12.93  ? 252 ALA B N   1 
ATOM 3564 C CA  . ALA B 1 252 ? 309.370 300.234 128.849 1.00 12.93  ? 252 ALA B CA  1 
ATOM 3565 C C   . ALA B 1 252 ? 308.647 299.225 129.729 1.00 12.93  ? 252 ALA B C   1 
ATOM 3566 O O   . ALA B 1 252 ? 308.870 298.023 129.609 1.00 12.93  ? 252 ALA B O   1 
ATOM 3567 C CB  . ALA B 1 252 ? 308.433 300.752 127.767 1.00 12.93  ? 252 ALA B CB  1 
ATOM 3568 N N   . PRO B 1 253 ? 307.791 299.682 130.643 1.00 11.18  ? 253 PRO B N   1 
ATOM 3569 C CA  . PRO B 1 253 ? 306.941 298.734 131.362 1.00 11.18  ? 253 PRO B CA  1 
ATOM 3570 C C   . PRO B 1 253 ? 305.898 298.128 130.440 1.00 11.18  ? 253 PRO B C   1 
ATOM 3571 O O   . PRO B 1 253 ? 305.373 298.787 129.542 1.00 11.18  ? 253 PRO B O   1 
ATOM 3572 C CB  . PRO B 1 253 ? 306.298 299.594 132.451 1.00 11.18  ? 253 PRO B CB  1 
ATOM 3573 C CG  . PRO B 1 253 ? 307.191 300.691 132.625 1.00 11.18  ? 253 PRO B CG  1 
ATOM 3574 C CD  . PRO B 1 253 ? 307.748 301.000 131.291 1.00 11.18  ? 253 PRO B CD  1 
ATOM 3575 N N   . ILE B 1 254 ? 305.613 296.865 130.657 1.00 11.38  ? 254 ILE B N   1 
ATOM 3576 C CA  . ILE B 1 254 ? 304.621 296.160 129.866 1.00 11.38  ? 254 ILE B CA  1 
ATOM 3577 C C   . ILE B 1 254 ? 303.343 296.061 130.679 1.00 11.38  ? 254 ILE B C   1 
ATOM 3578 O O   . ILE B 1 254 ? 303.360 296.053 131.913 1.00 11.38  ? 254 ILE B O   1 
ATOM 3579 C CB  . ILE B 1 254 ? 305.132 294.774 129.428 1.00 11.38  ? 254 ILE B CB  1 
ATOM 3580 C CG1 . ILE B 1 254 ? 305.404 293.888 130.641 1.00 11.38  ? 254 ILE B CG1 1 
ATOM 3581 C CG2 . ILE B 1 254 ? 306.397 294.921 128.627 1.00 11.38  ? 254 ILE B CG2 1 
ATOM 3582 C CD1 . ILE B 1 254 ? 305.146 292.416 130.407 1.00 11.38  ? 254 ILE B CD1 1 
ATOM 3583 N N   . LEU B 1 255 ? 302.217 296.018 129.979 1.00 14.19  ? 255 LEU B N   1 
ATOM 3584 C CA  . LEU B 1 255 ? 300.907 295.956 130.607 1.00 14.19  ? 255 LEU B CA  1 
ATOM 3585 C C   . LEU B 1 255 ? 300.424 294.515 130.587 1.00 14.19  ? 255 LEU B C   1 
ATOM 3586 O O   . LEU B 1 255 ? 300.311 293.909 129.517 1.00 14.19  ? 255 LEU B O   1 
ATOM 3587 C CB  . LEU B 1 255 ? 299.920 296.872 129.890 1.00 14.19  ? 255 LEU B CB  1 
ATOM 3588 C CG  . LEU B 1 255 ? 298.512 297.003 130.464 1.00 14.19  ? 255 LEU B CG  1 
ATOM 3589 C CD1 . LEU B 1 255 ? 298.505 297.134 131.973 1.00 14.19  ? 255 LEU B CD1 1 
ATOM 3590 C CD2 . LEU B 1 255 ? 297.826 298.177 129.837 1.00 14.19  ? 255 LEU B CD2 1 
ATOM 3591 N N   . SER B 1 256 ? 300.194 293.961 131.773 1.00 27.06  ? 256 SER B N   1 
ATOM 3592 C CA  . SER B 1 256 ? 299.538 292.675 131.951 1.00 27.06  ? 256 SER B CA  1 
ATOM 3593 C C   . SER B 1 256 ? 299.012 292.614 133.376 1.00 27.06  ? 256 SER B C   1 
ATOM 3594 O O   . SER B 1 256 ? 299.571 293.237 134.281 1.00 27.06  ? 256 SER B O   1 
ATOM 3595 C CB  . SER B 1 256 ? 300.470 291.495 131.661 1.00 27.06  ? 256 SER B CB  1 
ATOM 3596 O OG  . SER B 1 256 ? 300.787 291.434 130.280 1.00 27.06  ? 256 SER B OG  1 
ATOM 3597 N N   . THR B 1 257 ? 297.934 291.853 133.565 1.00 36.81  ? 257 THR B N   1 
ATOM 3598 C CA  . THR B 1 257 ? 297.137 291.980 134.781 1.00 36.81  ? 257 THR B CA  1 
ATOM 3599 C C   . THR B 1 257 ? 297.833 291.367 135.998 1.00 36.81  ? 257 THR B C   1 
ATOM 3600 O O   . THR B 1 257 ? 298.006 292.043 137.018 1.00 36.81  ? 257 THR B O   1 
ATOM 3601 C CB  . THR B 1 257 ? 295.730 291.399 134.550 1.00 36.81  ? 257 THR B CB  1 
ATOM 3602 O OG1 . THR B 1 257 ? 295.009 291.334 135.786 1.00 36.81  ? 257 THR B OG1 1 
ATOM 3603 C CG2 . THR B 1 257 ? 295.738 290.049 133.827 1.00 36.81  ? 257 THR B CG2 1 
ATOM 3604 N N   . LEU B 1 258 ? 298.271 290.110 135.891 1.00 49.80  ? 258 LEU B N   1 
ATOM 3605 C CA  . LEU B 1 258 ? 298.894 289.289 136.955 1.00 49.80  ? 258 LEU B CA  1 
ATOM 3606 C C   . LEU B 1 258 ? 298.285 289.369 138.375 1.00 49.80  ? 258 LEU B C   1 
ATOM 3607 O O   . LEU B 1 258 ? 298.903 288.936 139.346 1.00 49.80  ? 258 LEU B O   1 
ATOM 3608 C CB  . LEU B 1 258 ? 300.409 289.584 137.028 1.00 49.80  ? 258 LEU B CB  1 
ATOM 3609 C CG  . LEU B 1 258 ? 301.081 290.920 137.368 1.00 49.80  ? 258 LEU B CG  1 
ATOM 3610 C CD1 . LEU B 1 258 ? 301.347 291.079 138.862 1.00 49.80  ? 258 LEU B CD1 1 
ATOM 3611 C CD2 . LEU B 1 258 ? 302.371 291.061 136.582 1.00 49.80  ? 258 LEU B CD2 1 
ATOM 3612 N N   . ASN C 1 14  ? 269.122 263.719 70.218  1.00 80.53  ? 14  ASN C N   1 
ATOM 3613 C CA  . ASN C 1 14  ? 270.522 263.773 69.815  1.00 80.53  ? 14  ASN C CA  1 
ATOM 3614 C C   . ASN C 1 14  ? 271.315 264.485 70.913  1.00 80.53  ? 14  ASN C C   1 
ATOM 3615 O O   . ASN C 1 14  ? 270.800 265.382 71.579  1.00 80.53  ? 14  ASN C O   1 
ATOM 3616 C CB  . ASN C 1 14  ? 270.661 264.481 68.462  1.00 80.53  ? 14  ASN C CB  1 
ATOM 3617 C CG  . ASN C 1 14  ? 272.098 264.544 67.963  1.00 80.53  ? 14  ASN C CG  1 
ATOM 3618 O OD1 . ASN C 1 14  ? 272.959 263.779 68.398  1.00 80.53  ? 14  ASN C OD1 1 
ATOM 3619 N ND2 . ASN C 1 14  ? 272.359 265.460 67.038  1.00 80.53  ? 14  ASN C ND2 1 
ATOM 3620 N N   . GLU C 1 15  ? 272.573 264.080 71.096  1.00 87.18  ? 15  GLU C N   1 
ATOM 3621 C CA  . GLU C 1 15  ? 273.344 264.501 72.260  1.00 87.18  ? 15  GLU C CA  1 
ATOM 3622 C C   . GLU C 1 15  ? 273.997 265.869 72.093  1.00 87.18  ? 15  GLU C C   1 
ATOM 3623 O O   . GLU C 1 15  ? 274.417 266.460 73.094  1.00 87.18  ? 15  GLU C O   1 
ATOM 3624 C CB  . GLU C 1 15  ? 274.422 263.461 72.591  1.00 87.18  ? 15  GLU C CB  1 
ATOM 3625 C CG  . GLU C 1 15  ? 274.000 261.999 72.416  1.00 87.18  ? 15  GLU C CG  1 
ATOM 3626 C CD  . GLU C 1 15  ? 274.316 261.443 71.036  1.00 87.18  ? 15  GLU C CD  1 
ATOM 3627 O OE1 . GLU C 1 15  ? 274.702 262.232 70.149  1.00 87.18  ? 15  GLU C OE1 1 
ATOM 3628 O OE2 . GLU C 1 15  ? 274.176 260.217 70.839  1.00 87.18  ? 15  GLU C OE2 1 
ATOM 3629 N N   . ASN C 1 16  ? 274.102 266.384 70.864  1.00 87.39  ? 16  ASN C N   1 
ATOM 3630 C CA  . ASN C 1 16  ? 274.732 267.680 70.631  1.00 87.39  ? 16  ASN C CA  1 
ATOM 3631 C C   . ASN C 1 16  ? 273.980 268.496 69.584  1.00 87.39  ? 16  ASN C C   1 
ATOM 3632 O O   . ASN C 1 16  ? 274.578 269.333 68.899  1.00 87.39  ? 16  ASN C O   1 
ATOM 3633 C CB  . ASN C 1 16  ? 276.205 267.508 70.228  1.00 87.39  ? 16  ASN C CB  1 
ATOM 3634 C CG  . ASN C 1 16  ? 276.389 266.648 68.980  1.00 87.39  ? 16  ASN C CG  1 
ATOM 3635 O OD1 . ASN C 1 16  ? 276.066 267.055 67.862  1.00 87.39  ? 16  ASN C OD1 1 
ATOM 3636 N ND2 . ASN C 1 16  ? 276.913 265.444 69.175  1.00 87.39  ? 16  ASN C ND2 1 
ATOM 3637 N N   . SER C 1 17  ? 272.674 268.282 69.459  1.00 71.65  ? 17  SER C N   1 
ATOM 3638 C CA  . SER C 1 17  ? 271.900 268.913 68.402  1.00 71.65  ? 17  SER C CA  1 
ATOM 3639 C C   . SER C 1 17  ? 271.591 270.367 68.746  1.00 71.65  ? 17  SER C C   1 
ATOM 3640 O O   . SER C 1 17  ? 271.958 270.885 69.803  1.00 71.65  ? 17  SER C O   1 
ATOM 3641 C CB  . SER C 1 17  ? 270.608 268.140 68.154  1.00 71.65  ? 17  SER C CB  1 
ATOM 3642 O OG  . SER C 1 17  ? 269.664 268.932 67.455  1.00 71.65  ? 17  SER C OG  1 
ATOM 3643 N N   . LEU C 1 18  ? 270.906 271.037 67.822  1.00 68.55  ? 18  LEU C N   1 
ATOM 3644 C CA  . LEU C 1 18  ? 270.367 272.358 68.103  1.00 68.55  ? 18  LEU C CA  1 
ATOM 3645 C C   . LEU C 1 18  ? 269.040 272.284 68.842  1.00 68.55  ? 18  LEU C C   1 
ATOM 3646 O O   . LEU C 1 18  ? 268.650 273.264 69.486  1.00 68.55  ? 18  LEU C O   1 
ATOM 3647 C CB  . LEU C 1 18  ? 270.194 273.145 66.800  1.00 68.55  ? 18  LEU C CB  1 
ATOM 3648 C CG  . LEU C 1 18  ? 270.170 274.675 66.879  1.00 68.55  ? 18  LEU C CG  1 
ATOM 3649 C CD1 . LEU C 1 18  ? 271.271 275.192 67.793  1.00 68.55  ? 18  LEU C CD1 1 
ATOM 3650 C CD2 . LEU C 1 18  ? 270.288 275.288 65.495  1.00 68.55  ? 18  LEU C CD2 1 
ATOM 3651 N N   . GLU C 1 19  ? 268.347 271.143 68.772  1.00 73.07  ? 19  GLU C N   1 
ATOM 3652 C CA  . GLU C 1 19  ? 267.037 271.034 69.404  1.00 73.07  ? 19  GLU C CA  1 
ATOM 3653 C C   . GLU C 1 19  ? 267.148 270.974 70.923  1.00 73.07  ? 19  GLU C C   1 
ATOM 3654 O O   . GLU C 1 19  ? 266.289 271.522 71.620  1.00 73.07  ? 19  GLU C O   1 
ATOM 3655 C CB  . GLU C 1 19  ? 266.273 269.834 68.821  1.00 73.07  ? 19  GLU C CB  1 
ATOM 3656 C CG  . GLU C 1 19  ? 266.779 268.423 69.139  1.00 73.07  ? 19  GLU C CG  1 
ATOM 3657 C CD  . GLU C 1 19  ? 266.238 267.860 70.440  1.00 73.07  ? 19  GLU C CD  1 
ATOM 3658 O OE1 . GLU C 1 19  ? 266.802 266.865 70.937  1.00 73.07  ? 19  GLU C OE1 1 
ATOM 3659 O OE2 . GLU C 1 19  ? 265.251 268.416 70.966  1.00 73.07  ? 19  GLU C OE2 1 
ATOM 3660 N N   . ILE C 1 20  ? 268.210 270.361 71.455  1.00 72.30  ? 20  ILE C N   1 
ATOM 3661 C CA  . ILE C 1 20  ? 268.427 270.416 72.898  1.00 72.30  ? 20  ILE C CA  1 
ATOM 3662 C C   . ILE C 1 20  ? 268.847 271.815 73.328  1.00 72.30  ? 20  ILE C C   1 
ATOM 3663 O O   . ILE C 1 20  ? 268.561 272.232 74.454  1.00 72.30  ? 20  ILE C O   1 
ATOM 3664 C CB  . ILE C 1 20  ? 269.451 269.356 73.346  1.00 72.30  ? 20  ILE C CB  1 
ATOM 3665 C CG1 . ILE C 1 20  ? 270.756 269.487 72.559  1.00 72.30  ? 20  ILE C CG1 1 
ATOM 3666 C CG2 . ILE C 1 20  ? 268.862 267.960 73.250  1.00 72.30  ? 20  ILE C CG2 1 
ATOM 3667 C CD1 . ILE C 1 20  ? 271.879 268.648 73.107  1.00 72.30  ? 20  ILE C CD1 1 
ATOM 3668 N N   . GLU C 1 21  ? 269.493 272.576 72.442  1.00 73.66  ? 21  GLU C N   1 
ATOM 3669 C CA  . GLU C 1 21  ? 269.847 273.950 72.778  1.00 73.66  ? 21  GLU C CA  1 
ATOM 3670 C C   . GLU C 1 21  ? 268.613 274.847 72.788  1.00 73.66  ? 21  GLU C C   1 
ATOM 3671 O O   . GLU C 1 21  ? 268.481 275.712 73.664  1.00 73.66  ? 21  GLU C O   1 
ATOM 3672 C CB  . GLU C 1 21  ? 270.906 274.454 71.796  1.00 73.66  ? 21  GLU C CB  1 
ATOM 3673 C CG  . GLU C 1 21  ? 271.677 275.690 72.230  1.00 73.66  ? 21  GLU C CG  1 
ATOM 3674 C CD  . GLU C 1 21  ? 271.063 276.978 71.735  1.00 73.66  ? 21  GLU C CD  1 
ATOM 3675 O OE1 . GLU C 1 21  ? 270.924 277.137 70.505  1.00 73.66  ? 21  GLU C OE1 1 
ATOM 3676 O OE2 . GLU C 1 21  ? 270.744 277.845 72.568  1.00 73.66  ? 21  GLU C OE2 1 
ATOM 3677 N N   . GLU C 1 22  ? 267.679 274.618 71.861  1.00 75.47  ? 22  GLU C N   1 
ATOM 3678 C CA  . GLU C 1 22  ? 266.409 275.338 71.895  1.00 75.47  ? 22  GLU C CA  1 
ATOM 3679 C C   . GLU C 1 22  ? 265.559 274.907 73.084  1.00 75.47  ? 22  GLU C C   1 
ATOM 3680 O O   . GLU C 1 22  ? 264.836 275.725 73.664  1.00 75.47  ? 22  GLU C O   1 
ATOM 3681 C CB  . GLU C 1 22  ? 265.642 275.128 70.588  1.00 75.47  ? 22  GLU C CB  1 
ATOM 3682 C CG  . GLU C 1 22  ? 266.344 275.607 69.317  1.00 75.47  ? 22  GLU C CG  1 
ATOM 3683 C CD  . GLU C 1 22  ? 267.084 276.925 69.480  1.00 75.47  ? 22  GLU C CD  1 
ATOM 3684 O OE1 . GLU C 1 22  ? 266.460 277.926 69.896  1.00 75.47  ? 22  GLU C OE1 1 
ATOM 3685 O OE2 . GLU C 1 22  ? 268.297 276.960 69.186  1.00 75.47  ? 22  GLU C OE2 1 
ATOM 3686 N N   . LEU C 1 23  ? 265.644 273.630 73.468  1.00 73.42  ? 23  LEU C N   1 
ATOM 3687 C CA  . LEU C 1 23  ? 264.949 273.163 74.664  1.00 73.42  ? 23  LEU C CA  1 
ATOM 3688 C C   . LEU C 1 23  ? 265.538 273.787 75.921  1.00 73.42  ? 23  LEU C C   1 
ATOM 3689 O O   . LEU C 1 23  ? 264.805 274.111 76.861  1.00 73.42  ? 23  LEU C O   1 
ATOM 3690 C CB  . LEU C 1 23  ? 265.013 271.640 74.745  1.00 73.42  ? 23  LEU C CB  1 
ATOM 3691 C CG  . LEU C 1 23  ? 263.793 270.893 74.210  1.00 73.42  ? 23  LEU C CG  1 
ATOM 3692 C CD1 . LEU C 1 23  ? 264.029 269.392 74.238  1.00 73.42  ? 23  LEU C CD1 1 
ATOM 3693 C CD2 . LEU C 1 23  ? 262.545 271.267 74.992  1.00 73.42  ? 23  LEU C CD2 1 
ATOM 3694 N N   . ALA C 1 24  ? 266.857 273.987 75.942  1.00 73.70  ? 24  ALA C N   1 
ATOM 3695 C CA  . ALA C 1 24  ? 267.498 274.654 77.069  1.00 73.70  ? 24  ALA C CA  1 
ATOM 3696 C C   . ALA C 1 24  ? 267.122 276.128 77.129  1.00 73.70  ? 24  ALA C C   1 
ATOM 3697 O O   . ALA C 1 24  ? 266.938 276.680 78.219  1.00 73.70  ? 24  ALA C O   1 
ATOM 3698 C CB  . ALA C 1 24  ? 269.012 274.488 76.976  1.00 73.70  ? 24  ALA C CB  1 
ATOM 3699 N N   . ARG C 1 25  ? 266.992 276.778 75.968  1.00 79.23  ? 25  ARG C N   1 
ATOM 3700 C CA  . ARG C 1 25  ? 266.539 278.169 75.946  1.00 79.23  ? 25  ARG C CA  1 
ATOM 3701 C C   . ARG C 1 25  ? 265.088 278.291 76.401  1.00 79.23  ? 25  ARG C C   1 
ATOM 3702 O O   . ARG C 1 25  ? 264.737 279.234 77.125  1.00 79.23  ? 25  ARG C O   1 
ATOM 3703 C CB  . ARG C 1 25  ? 266.711 278.759 74.550  1.00 79.23  ? 25  ARG C CB  1 
ATOM 3704 C CG  . ARG C 1 25  ? 268.154 278.980 74.178  1.00 79.23  ? 25  ARG C CG  1 
ATOM 3705 C CD  . ARG C 1 25  ? 268.329 280.121 73.199  1.00 79.23  ? 25  ARG C CD  1 
ATOM 3706 N NE  . ARG C 1 25  ? 269.743 280.397 72.967  1.00 79.23  ? 25  ARG C NE  1 
ATOM 3707 C CZ  . ARG C 1 25  ? 270.483 281.204 73.719  1.00 79.23  ? 25  ARG C CZ  1 
ATOM 3708 N NH1 . ARG C 1 25  ? 269.943 281.831 74.756  1.00 79.23  ? 25  ARG C NH1 1 
ATOM 3709 N NH2 . ARG C 1 25  ? 271.763 281.389 73.432  1.00 79.23  ? 25  ARG C NH2 1 
ATOM 3710 N N   . PHE C 1 26  ? 264.240 277.341 75.992  1.00 78.64  ? 26  PHE C N   1 
ATOM 3711 C CA  . PHE C 1 26  ? 262.857 277.318 76.457  1.00 78.64  ? 26  PHE C CA  1 
ATOM 3712 C C   . PHE C 1 26  ? 262.785 277.076 77.958  1.00 78.64  ? 26  PHE C C   1 
ATOM 3713 O O   . PHE C 1 26  ? 261.976 277.698 78.653  1.00 78.64  ? 26  PHE C O   1 
ATOM 3714 C CB  . PHE C 1 26  ? 262.066 276.249 75.704  1.00 78.64  ? 26  PHE C CB  1 
ATOM 3715 C CG  . PHE C 1 26  ? 260.863 275.741 76.452  1.00 78.64  ? 26  PHE C CG  1 
ATOM 3716 C CD1 . PHE C 1 26  ? 259.730 276.528 76.584  1.00 78.64  ? 26  PHE C CD1 1 
ATOM 3717 C CD2 . PHE C 1 26  ? 260.861 274.471 77.013  1.00 78.64  ? 26  PHE C CD2 1 
ATOM 3718 C CE1 . PHE C 1 26  ? 258.626 276.064 77.271  1.00 78.64  ? 26  PHE C CE1 1 
ATOM 3719 C CE2 . PHE C 1 26  ? 259.759 274.005 77.701  1.00 78.64  ? 26  PHE C CE2 1 
ATOM 3720 C CZ  . PHE C 1 26  ? 258.641 274.801 77.828  1.00 78.64  ? 26  PHE C CZ  1 
ATOM 3721 N N   . ALA C 1 27  ? 263.636 276.190 78.477  1.00 73.27  ? 27  ALA C N   1 
ATOM 3722 C CA  . ALA C 1 27  ? 263.647 275.931 79.912  1.00 73.27  ? 27  ALA C CA  1 
ATOM 3723 C C   . ALA C 1 27  ? 264.130 277.147 80.688  1.00 73.27  ? 27  ALA C C   1 
ATOM 3724 O O   . ALA C 1 27  ? 263.554 277.496 81.725  1.00 73.27  ? 27  ALA C O   1 
ATOM 3725 C CB  . ALA C 1 27  ? 264.518 274.717 80.221  1.00 73.27  ? 27  ALA C CB  1 
ATOM 3726 N N   . VAL C 1 28  ? 265.153 277.835 80.181  1.00 76.59  ? 28  VAL C N   1 
ATOM 3727 C CA  . VAL C 1 28  ? 265.688 278.949 80.948  1.00 76.59  ? 28  VAL C CA  1 
ATOM 3728 C C   . VAL C 1 28  ? 264.758 280.164 80.881  1.00 76.59  ? 28  VAL C C   1 
ATOM 3729 O O   . VAL C 1 28  ? 264.580 280.853 81.891  1.00 76.59  ? 28  VAL C O   1 
ATOM 3730 C CB  . VAL C 1 28  ? 267.137 279.261 80.517  1.00 76.59  ? 28  VAL C CB  1 
ATOM 3731 C CG1 . VAL C 1 28  ? 267.224 279.993 79.180  1.00 76.59  ? 28  VAL C CG1 1 
ATOM 3732 C CG2 . VAL C 1 28  ? 267.852 280.030 81.604  1.00 76.59  ? 28  VAL C CG2 1 
ATOM 3733 N N   . ASP C 1 29  ? 264.056 280.395 79.761  1.00 81.17  ? 29  ASP C N   1 
ATOM 3734 C CA  . ASP C 1 29  ? 263.124 281.514 79.777  1.00 81.17  ? 29  ASP C CA  1 
ATOM 3735 C C   . ASP C 1 29  ? 261.807 281.153 80.452  1.00 81.17  ? 29  ASP C C   1 
ATOM 3736 O O   . ASP C 1 29  ? 261.137 282.045 80.979  1.00 81.17  ? 29  ASP C O   1 
ATOM 3737 C CB  . ASP C 1 29  ? 262.949 282.110 78.360  1.00 81.17  ? 29  ASP C CB  1 
ATOM 3738 C CG  . ASP C 1 29  ? 262.278 281.176 77.333  1.00 81.17  ? 29  ASP C CG  1 
ATOM 3739 O OD1 . ASP C 1 29  ? 261.481 280.272 77.645  1.00 81.17  ? 29  ASP C OD1 1 
ATOM 3740 O OD2 . ASP C 1 29  ? 262.585 281.370 76.139  1.00 81.17  ? 29  ASP C OD2 1 
ATOM 3741 N N   . GLU C 1 30  ? 261.460 279.863 80.510  1.00 74.71  ? 30  GLU C N   1 
ATOM 3742 C CA  . GLU C 1 30  ? 260.299 279.447 81.285  1.00 74.71  ? 30  GLU C CA  1 
ATOM 3743 C C   . GLU C 1 30  ? 260.546 279.606 82.777  1.00 74.71  ? 30  GLU C C   1 
ATOM 3744 O O   . GLU C 1 30  ? 259.665 280.075 83.506  1.00 74.71  ? 30  GLU C O   1 
ATOM 3745 C CB  . GLU C 1 30  ? 259.945 278.001 80.949  1.00 74.71  ? 30  GLU C CB  1 
ATOM 3746 C CG  . GLU C 1 30  ? 258.581 277.568 81.435  1.00 74.71  ? 30  GLU C CG  1 
ATOM 3747 C CD  . GLU C 1 30  ? 257.453 278.090 80.571  1.00 74.71  ? 30  GLU C CD  1 
ATOM 3748 O OE1 . GLU C 1 30  ? 257.722 278.553 79.443  1.00 74.71  ? 30  GLU C OE1 1 
ATOM 3749 O OE2 . GLU C 1 30  ? 256.290 278.032 81.020  1.00 74.71  ? 30  GLU C OE2 1 
ATOM 3750 N N   . HIS C 1 31  ? 261.744 279.243 83.245  1.00 71.59  ? 31  HIS C N   1 
ATOM 3751 C CA  . HIS C 1 31  ? 262.090 279.493 84.641  1.00 71.59  ? 31  HIS C CA  1 
ATOM 3752 C C   . HIS C 1 31  ? 262.205 280.987 84.924  1.00 71.59  ? 31  HIS C C   1 
ATOM 3753 O O   . HIS C 1 31  ? 261.810 281.447 86.003  1.00 71.59  ? 31  HIS C O   1 
ATOM 3754 C CB  . HIS C 1 31  ? 263.392 278.784 85.003  1.00 71.59  ? 31  HIS C CB  1 
ATOM 3755 C CG  . HIS C 1 31  ? 263.943 279.186 86.336  1.00 71.59  ? 31  HIS C CG  1 
ATOM 3756 N ND1 . HIS C 1 31  ? 263.498 278.638 87.518  1.00 71.59  ? 31  HIS C ND1 1 
ATOM 3757 C CD2 . HIS C 1 31  ? 264.897 280.084 86.675  1.00 71.59  ? 31  HIS C CD2 1 
ATOM 3758 C CE1 . HIS C 1 31  ? 264.151 279.182 88.528  1.00 71.59  ? 31  HIS C CE1 1 
ATOM 3759 N NE2 . HIS C 1 31  ? 265.006 280.063 88.043  1.00 71.59  ? 31  HIS C NE2 1 
ATOM 3760 N N   . ASN C 1 32  ? 262.726 281.754 83.957  1.00 75.56  ? 32  ASN C N   1 
ATOM 3761 C CA  . ASN C 1 32  ? 262.838 283.201 84.108  1.00 75.56  ? 32  ASN C CA  1 
ATOM 3762 C C   . ASN C 1 32  ? 261.471 283.858 84.236  1.00 75.56  ? 32  ASN C C   1 
ATOM 3763 O O   . ASN C 1 32  ? 261.287 284.777 85.042  1.00 75.56  ? 32  ASN C O   1 
ATOM 3764 C CB  . ASN C 1 32  ? 263.582 283.785 82.910  1.00 75.56  ? 32  ASN C CB  1 
ATOM 3765 C CG  . ASN C 1 32  ? 265.071 283.842 83.122  1.00 75.56  ? 32  ASN C CG  1 
ATOM 3766 O OD1 . ASN C 1 32  ? 265.571 283.457 84.176  1.00 75.56  ? 32  ASN C OD1 1 
ATOM 3767 N ND2 . ASN C 1 32  ? 265.794 284.328 82.119  1.00 75.56  ? 32  ASN C ND2 1 
ATOM 3768 N N   . LYS C 1 33  ? 260.495 283.394 83.455  1.00 72.96  ? 33  LYS C N   1 
ATOM 3769 C CA  . LYS C 1 33  ? 259.164 283.980 83.523  1.00 72.96  ? 33  LYS C CA  1 
ATOM 3770 C C   . LYS C 1 33  ? 258.412 283.508 84.758  1.00 72.96  ? 33  LYS C C   1 
ATOM 3771 O O   . LYS C 1 33  ? 257.701 284.296 85.391  1.00 72.96  ? 33  LYS C O   1 
ATOM 3772 C CB  . LYS C 1 33  ? 258.376 283.645 82.259  1.00 72.96  ? 33  LYS C CB  1 
ATOM 3773 C CG  . LYS C 1 33  ? 258.823 284.415 81.029  1.00 72.96  ? 33  LYS C CG  1 
ATOM 3774 C CD  . LYS C 1 33  ? 257.682 284.610 80.042  1.00 72.96  ? 33  LYS C CD  1 
ATOM 3775 C CE  . LYS C 1 33  ? 256.983 283.298 79.718  1.00 72.96  ? 33  LYS C CE  1 
ATOM 3776 N NZ  . LYS C 1 33  ? 257.910 282.309 79.107  1.00 72.96  ? 33  LYS C NZ  1 
ATOM 3777 N N   . LYS C 1 34  ? 258.557 282.235 85.129  1.00 71.76  ? 34  LYS C N   1 
ATOM 3778 C CA  . LYS C 1 34  ? 257.748 281.709 86.221  1.00 71.76  ? 34  LYS C CA  1 
ATOM 3779 C C   . LYS C 1 34  ? 258.329 282.070 87.583  1.00 71.76  ? 34  LYS C C   1 
ATOM 3780 O O   . LYS C 1 34  ? 257.682 282.759 88.376  1.00 71.76  ? 34  LYS C O   1 
ATOM 3781 C CB  . LYS C 1 34  ? 257.591 280.196 86.079  1.00 71.76  ? 34  LYS C CB  1 
ATOM 3782 C CG  . LYS C 1 34  ? 256.344 279.772 85.337  1.00 71.76  ? 34  LYS C CG  1 
ATOM 3783 C CD  . LYS C 1 34  ? 256.629 278.601 84.421  1.00 71.76  ? 34  LYS C CD  1 
ATOM 3784 C CE  . LYS C 1 34  ? 257.093 277.389 85.203  1.00 71.76  ? 34  LYS C CE  1 
ATOM 3785 N NZ  . LYS C 1 34  ? 257.220 276.184 84.342  1.00 71.76  ? 34  LYS C NZ  1 
ATOM 3786 N N   . GLU C 1 35  ? 259.553 281.629 87.878  1.00 73.18  ? 35  GLU C N   1 
ATOM 3787 C CA  . GLU C 1 35  ? 260.096 281.805 89.220  1.00 73.18  ? 35  GLU C CA  1 
ATOM 3788 C C   . GLU C 1 35  ? 260.755 283.163 89.431  1.00 73.18  ? 35  GLU C C   1 
ATOM 3789 O O   . GLU C 1 35  ? 261.401 283.355 90.467  1.00 73.18  ? 35  GLU C O   1 
ATOM 3790 C CB  . GLU C 1 35  ? 261.092 280.693 89.563  1.00 73.18  ? 35  GLU C CB  1 
ATOM 3791 C CG  . GLU C 1 35  ? 260.468 279.328 89.797  1.00 73.18  ? 35  GLU C CG  1 
ATOM 3792 C CD  . GLU C 1 35  ? 260.511 278.438 88.574  1.00 73.18  ? 35  GLU C CD  1 
ATOM 3793 O OE1 . GLU C 1 35  ? 260.203 278.926 87.473  1.00 73.18  ? 35  GLU C OE1 1 
ATOM 3794 O OE2 . GLU C 1 35  ? 260.854 277.243 88.714  1.00 73.18  ? 35  GLU C OE2 1 
ATOM 3795 N N   . ASN C 1 36  ? 260.605 284.087 88.475  1.00 71.94  ? 36  ASN C N   1 
ATOM 3796 C CA  . ASN C 1 36  ? 261.045 285.486 88.570  1.00 71.94  ? 36  ASN C CA  1 
ATOM 3797 C C   . ASN C 1 36  ? 262.555 285.590 88.818  1.00 71.94  ? 36  ASN C C   1 
ATOM 3798 O O   . ASN C 1 36  ? 263.019 286.007 89.881  1.00 71.94  ? 36  ASN C O   1 
ATOM 3799 C CB  . ASN C 1 36  ? 260.250 286.244 89.641  1.00 71.94  ? 36  ASN C CB  1 
ATOM 3800 C CG  . ASN C 1 36  ? 260.514 287.731 89.615  1.00 71.94  ? 36  ASN C CG  1 
ATOM 3801 O OD1 . ASN C 1 36  ? 260.840 288.332 90.637  1.00 71.94  ? 36  ASN C OD1 1 
ATOM 3802 N ND2 . ASN C 1 36  ? 260.357 288.336 88.450  1.00 71.94  ? 36  ASN C ND2 1 
ATOM 3803 N N   . ALA C 1 37  ? 263.320 285.155 87.827  1.00 72.67  ? 37  ALA C N   1 
ATOM 3804 C CA  . ALA C 1 37  ? 264.767 285.275 87.861  1.00 72.67  ? 37  ALA C CA  1 
ATOM 3805 C C   . ALA C 1 37  ? 265.252 285.687 86.479  1.00 72.67  ? 37  ALA C C   1 
ATOM 3806 O O   . ALA C 1 37  ? 264.471 285.774 85.529  1.00 72.67  ? 37  ALA C O   1 
ATOM 3807 C CB  . ALA C 1 37  ? 265.416 283.970 88.321  1.00 72.67  ? 37  ALA C CB  1 
ATOM 3808 N N   . LEU C 1 38  ? 266.545 285.991 86.375  1.00 74.29  ? 38  LEU C N   1 
ATOM 3809 C CA  . LEU C 1 38  ? 267.173 286.314 85.091  1.00 74.29  ? 38  LEU C CA  1 
ATOM 3810 C C   . LEU C 1 38  ? 268.432 285.466 84.960  1.00 74.29  ? 38  LEU C C   1 
ATOM 3811 O O   . LEU C 1 38  ? 269.490 285.810 85.492  1.00 74.29  ? 38  LEU C O   1 
ATOM 3812 C CB  . LEU C 1 38  ? 267.488 287.797 84.956  1.00 74.29  ? 38  LEU C CB  1 
ATOM 3813 C CG  . LEU C 1 38  ? 267.388 288.243 83.492  1.00 74.29  ? 38  LEU C CG  1 
ATOM 3814 C CD1 . LEU C 1 38  ? 265.936 288.249 83.009  1.00 74.29  ? 38  LEU C CD1 1 
ATOM 3815 C CD2 . LEU C 1 38  ? 268.076 289.572 83.226  1.00 74.29  ? 38  LEU C CD2 1 
ATOM 3816 N N   . LEU C 1 39  ? 268.311 284.360 84.240  1.00 72.63  ? 39  LEU C N   1 
ATOM 3817 C CA  . LEU C 1 39  ? 269.397 283.413 84.038  1.00 72.63  ? 39  LEU C CA  1 
ATOM 3818 C C   . LEU C 1 39  ? 269.770 283.398 82.563  1.00 72.63  ? 39  LEU C C   1 
ATOM 3819 O O   . LEU C 1 39  ? 268.909 283.185 81.704  1.00 72.63  ? 39  LEU C O   1 
ATOM 3820 C CB  . LEU C 1 39  ? 268.989 282.021 84.517  1.00 72.63  ? 39  LEU C CB  1 
ATOM 3821 C CG  . LEU C 1 39  ? 269.264 281.622 85.967  1.00 72.63  ? 39  LEU C CG  1 
ATOM 3822 C CD1 . LEU C 1 39  ? 268.357 282.322 86.916  1.00 72.63  ? 39  LEU C CD1 1 
ATOM 3823 C CD2 . LEU C 1 39  ? 269.030 280.142 86.107  1.00 72.63  ? 39  LEU C CD2 1 
ATOM 3824 N N   . GLU C 1 40  ? 271.045 283.642 82.274  1.00 82.54  ? 40  GLU C N   1 
ATOM 3825 C CA  . GLU C 1 40  ? 271.557 283.623 80.909  1.00 82.54  ? 40  GLU C CA  1 
ATOM 3826 C C   . GLU C 1 40  ? 272.166 282.253 80.638  1.00 82.54  ? 40  GLU C C   1 
ATOM 3827 O O   . GLU C 1 40  ? 273.247 281.937 81.143  1.00 82.54  ? 40  GLU C O   1 
ATOM 3828 C CB  . GLU C 1 40  ? 272.589 284.729 80.696  1.00 82.54  ? 40  GLU C CB  1 
ATOM 3829 C CG  . GLU C 1 40  ? 272.068 286.154 80.863  1.00 82.54  ? 40  GLU C CG  1 
ATOM 3830 C CD  . GLU C 1 40  ? 272.179 286.684 82.285  1.00 82.54  ? 40  GLU C CD  1 
ATOM 3831 O OE1 . GLU C 1 40  ? 272.564 287.862 82.444  1.00 82.54  ? 40  GLU C OE1 1 
ATOM 3832 O OE2 . GLU C 1 40  ? 271.871 285.942 83.240  1.00 82.54  ? 40  GLU C OE2 1 
ATOM 3833 N N   . PHE C 1 41  ? 271.481 281.449 79.831  1.00 79.48  ? 41  PHE C N   1 
ATOM 3834 C CA  . PHE C 1 41  ? 271.961 280.111 79.517  1.00 79.48  ? 41  PHE C CA  1 
ATOM 3835 C C   . PHE C 1 41  ? 273.144 280.182 78.558  1.00 79.48  ? 41  PHE C C   1 
ATOM 3836 O O   . PHE C 1 41  ? 273.147 280.969 77.609  1.00 79.48  ? 41  PHE C O   1 
ATOM 3837 C CB  . PHE C 1 41  ? 270.822 279.285 78.919  1.00 79.48  ? 41  PHE C CB  1 
ATOM 3838 C CG  . PHE C 1 41  ? 271.263 278.237 77.945  1.00 79.48  ? 41  PHE C CG  1 
ATOM 3839 C CD1 . PHE C 1 41  ? 271.820 277.053 78.393  1.00 79.48  ? 41  PHE C CD1 1 
ATOM 3840 C CD2 . PHE C 1 41  ? 271.094 278.423 76.580  1.00 79.48  ? 41  PHE C CD2 1 
ATOM 3841 C CE1 . PHE C 1 41  ? 272.222 276.088 77.502  1.00 79.48  ? 41  PHE C CE1 1 
ATOM 3842 C CE2 . PHE C 1 41  ? 271.499 277.459 75.684  1.00 79.48  ? 41  PHE C CE2 1 
ATOM 3843 C CZ  . PHE C 1 41  ? 272.063 276.290 76.145  1.00 79.48  ? 41  PHE C CZ  1 
ATOM 3844 N N   . VAL C 1 42  ? 274.156 279.348 78.808  1.00 79.18  ? 42  VAL C N   1 
ATOM 3845 C CA  . VAL C 1 42  ? 275.346 279.326 77.964  1.00 79.18  ? 42  VAL C CA  1 
ATOM 3846 C C   . VAL C 1 42  ? 275.458 278.001 77.219  1.00 79.18  ? 42  VAL C C   1 
ATOM 3847 O O   . VAL C 1 42  ? 275.399 277.969 75.985  1.00 79.18  ? 42  VAL C O   1 
ATOM 3848 C CB  . VAL C 1 42  ? 276.621 279.591 78.786  1.00 79.18  ? 42  VAL C CB  1 
ATOM 3849 C CG1 . VAL C 1 42  ? 277.793 279.887 77.864  1.00 79.18  ? 42  VAL C CG1 1 
ATOM 3850 C CG2 . VAL C 1 42  ? 276.406 280.735 79.763  1.00 79.18  ? 42  VAL C CG2 1 
ATOM 3851 N N   . ARG C 1 43  ? 275.613 276.900 77.953  1.00 80.56  ? 43  ARG C N   1 
ATOM 3852 C CA  . ARG C 1 43  ? 275.896 275.616 77.326  1.00 80.56  ? 43  ARG C CA  1 
ATOM 3853 C C   . ARG C 1 43  ? 275.169 274.500 78.062  1.00 80.56  ? 43  ARG C C   1 
ATOM 3854 O O   . ARG C 1 43  ? 274.810 274.636 79.235  1.00 80.56  ? 43  ARG C O   1 
ATOM 3855 C CB  . ARG C 1 43  ? 277.403 275.332 77.296  1.00 80.56  ? 43  ARG C CB  1 
ATOM 3856 C CG  . ARG C 1 43  ? 278.016 275.098 78.666  1.00 80.56  ? 43  ARG C CG  1 
ATOM 3857 C CD  . ARG C 1 43  ? 279.527 275.006 78.604  1.00 80.56  ? 43  ARG C CD  1 
ATOM 3858 N NE  . ARG C 1 43  ? 280.110 274.850 79.932  1.00 80.56  ? 43  ARG C NE  1 
ATOM 3859 C CZ  . ARG C 1 43  ? 280.373 273.679 80.498  1.00 80.56  ? 43  ARG C CZ  1 
ATOM 3860 N NH1 . ARG C 1 43  ? 280.109 272.553 79.851  1.00 80.56  ? 43  ARG C NH1 1 
ATOM 3861 N NH2 . ARG C 1 43  ? 280.904 273.632 81.711  1.00 80.56  ? 43  ARG C NH2 1 
ATOM 3862 N N   . VAL C 1 44  ? 274.940 273.399 77.348  1.00 77.43  ? 44  VAL C N   1 
ATOM 3863 C CA  . VAL C 1 44  ? 274.322 272.204 77.909  1.00 77.43  ? 44  VAL C CA  1 
ATOM 3864 C C   . VAL C 1 44  ? 275.422 271.199 78.219  1.00 77.43  ? 44  VAL C C   1 
ATOM 3865 O O   . VAL C 1 44  ? 276.417 271.107 77.491  1.00 77.43  ? 44  VAL C O   1 
ATOM 3866 C CB  . VAL C 1 44  ? 273.285 271.609 76.936  1.00 77.43  ? 44  VAL C CB  1 
ATOM 3867 C CG1 . VAL C 1 44  ? 272.366 270.632 77.651  1.00 77.43  ? 44  VAL C CG1 1 
ATOM 3868 C CG2 . VAL C 1 44  ? 272.485 272.701 76.264  1.00 77.43  ? 44  VAL C CG2 1 
ATOM 3869 N N   . VAL C 1 45  ? 275.255 270.448 79.305  1.00 73.92  ? 45  VAL C N   1 
ATOM 3870 C CA  . VAL C 1 45  ? 276.218 269.424 79.680  1.00 73.92  ? 45  VAL C CA  1 
ATOM 3871 C C   . VAL C 1 45  ? 275.656 268.007 79.582  1.00 73.92  ? 45  VAL C C   1 
ATOM 3872 O O   . VAL C 1 45  ? 276.448 267.054 79.526  1.00 73.92  ? 45  VAL C O   1 
ATOM 3873 C CB  . VAL C 1 45  ? 276.781 269.676 81.096  1.00 73.92  ? 45  VAL C CB  1 
ATOM 3874 C CG1 . VAL C 1 45  ? 277.291 271.097 81.220  1.00 73.92  ? 45  VAL C CG1 1 
ATOM 3875 C CG2 . VAL C 1 45  ? 275.732 269.397 82.153  1.00 73.92  ? 45  VAL C CG2 1 
ATOM 3876 N N   . LYS C 1 46  ? 274.336 267.833 79.540  1.00 71.41  ? 46  LYS C N   1 
ATOM 3877 C CA  . LYS C 1 46  ? 273.746 266.503 79.613  1.00 71.41  ? 46  LYS C CA  1 
ATOM 3878 C C   . LYS C 1 46  ? 272.336 266.567 79.039  1.00 71.41  ? 46  LYS C C   1 
ATOM 3879 O O   . LYS C 1 46  ? 271.649 267.583 79.168  1.00 71.41  ? 46  LYS C O   1 
ATOM 3880 C CB  . LYS C 1 46  ? 273.748 265.993 81.068  1.00 71.41  ? 46  LYS C CB  1 
ATOM 3881 C CG  . LYS C 1 46  ? 273.188 264.583 81.328  1.00 71.41  ? 46  LYS C CG  1 
ATOM 3882 C CD  . LYS C 1 46  ? 271.720 264.586 81.750  1.00 71.41  ? 46  LYS C CD  1 
ATOM 3883 C CE  . LYS C 1 46  ? 271.575 264.969 83.206  1.00 71.41  ? 46  LYS C CE  1 
ATOM 3884 N NZ  . LYS C 1 46  ? 270.147 265.174 83.587  1.00 71.41  ? 46  LYS C NZ  1 
ATOM 3885 N N   . ALA C 1 47  ? 271.915 265.468 78.411  1.00 68.18  ? 47  ALA C N   1 
ATOM 3886 C CA  . ALA C 1 47  ? 270.559 265.346 77.880  1.00 68.18  ? 47  ALA C CA  1 
ATOM 3887 C C   . ALA C 1 47  ? 270.195 263.868 77.832  1.00 68.18  ? 47  ALA C C   1 
ATOM 3888 O O   . ALA C 1 47  ? 270.765 263.120 77.033  1.00 68.18  ? 47  ALA C O   1 
ATOM 3889 C CB  . ALA C 1 47  ? 270.454 265.981 76.495  1.00 68.18  ? 47  ALA C CB  1 
ATOM 3890 N N   . LYS C 1 48  ? 269.252 263.446 78.676  1.00 81.71  ? 48  LYS C N   1 
ATOM 3891 C CA  . LYS C 1 48  ? 268.786 262.061 78.707  1.00 81.71  ? 48  LYS C CA  1 
ATOM 3892 C C   . LYS C 1 48  ? 267.435 261.961 78.006  1.00 81.71  ? 48  LYS C C   1 
ATOM 3893 O O   . LYS C 1 48  ? 266.453 262.567 78.445  1.00 81.71  ? 48  LYS C O   1 
ATOM 3894 C CB  . LYS C 1 48  ? 268.679 261.532 80.136  1.00 81.71  ? 48  LYS C CB  1 
ATOM 3895 C CG  . LYS C 1 48  ? 269.989 261.065 80.740  1.00 81.71  ? 48  LYS C CG  1 
ATOM 3896 C CD  . LYS C 1 48  ? 269.777 260.540 82.150  1.00 81.71  ? 48  LYS C CD  1 
ATOM 3897 C CE  . LYS C 1 48  ? 270.137 261.574 83.191  1.00 81.71  ? 48  LYS C CE  1 
ATOM 3898 N NZ  . LYS C 1 48  ? 269.224 261.554 84.364  1.00 81.71  ? 48  LYS C NZ  1 
ATOM 3899 N N   . GLU C 1 49  ? 267.387 261.181 76.930  1.00 89.76  ? 49  GLU C N   1 
ATOM 3900 C CA  . GLU C 1 49  ? 266.142 260.922 76.219  1.00 89.76  ? 49  GLU C CA  1 
ATOM 3901 C C   . GLU C 1 49  ? 265.399 259.755 76.858  1.00 89.76  ? 49  GLU C C   1 
ATOM 3902 O O   . GLU C 1 49  ? 265.993 258.710 77.142  1.00 89.76  ? 49  GLU C O   1 
ATOM 3903 C CB  . GLU C 1 49  ? 266.433 260.627 74.747  1.00 89.76  ? 49  GLU C CB  1 
ATOM 3904 C CG  . GLU C 1 49  ? 265.224 260.236 73.906  1.00 89.76  ? 49  GLU C CG  1 
ATOM 3905 C CD  . GLU C 1 49  ? 264.062 261.198 74.039  1.00 89.76  ? 49  GLU C CD  1 
ATOM 3906 O OE1 . GLU C 1 49  ? 263.127 260.914 74.815  1.00 89.76  ? 49  GLU C OE1 1 
ATOM 3907 O OE2 . GLU C 1 49  ? 264.076 262.237 73.352  1.00 89.76  ? 49  GLU C OE2 1 
ATOM 3908 N N   . GLN C 1 50  ? 264.094 259.931 77.081  1.00 85.53  ? 50  GLN C N   1 
ATOM 3909 C CA  . GLN C 1 50  ? 263.255 258.871 77.640  1.00 85.53  ? 50  GLN C CA  1 
ATOM 3910 C C   . GLN C 1 50  ? 261.923 258.917 76.895  1.00 85.53  ? 50  GLN C C   1 
ATOM 3911 O O   . GLN C 1 50  ? 261.150 259.864 77.060  1.00 85.53  ? 50  GLN C O   1 
ATOM 3912 C CB  . GLN C 1 50  ? 263.072 259.043 79.145  1.00 85.53  ? 50  GLN C CB  1 
ATOM 3913 C CG  . GLN C 1 50  ? 262.486 257.838 79.892  1.00 85.53  ? 50  GLN C CG  1 
ATOM 3914 C CD  . GLN C 1 50  ? 260.974 257.734 79.776  1.00 85.53  ? 50  GLN C CD  1 
ATOM 3915 O OE1 . GLN C 1 50  ? 260.280 258.743 79.680  1.00 85.53  ? 50  GLN C OE1 1 
ATOM 3916 N NE2 . GLN C 1 50  ? 260.462 256.512 79.772  1.00 85.53  ? 50  GLN C NE2 1 
ATOM 3917 N N   . ILE C 1 51  ? 261.673 257.901 76.076  1.00 82.37  ? 51  ILE C N   1 
ATOM 3918 C CA  . ILE C 1 51  ? 260.416 257.793 75.346  1.00 82.37  ? 51  ILE C CA  1 
ATOM 3919 C C   . ILE C 1 51  ? 259.366 257.162 76.251  1.00 82.37  ? 51  ILE C C   1 
ATOM 3920 O O   . ILE C 1 51  ? 259.633 256.181 76.955  1.00 82.37  ? 51  ILE C O   1 
ATOM 3921 C CB  . ILE C 1 51  ? 260.625 256.974 74.055  1.00 82.37  ? 51  ILE C CB  1 
ATOM 3922 C CG1 . ILE C 1 51  ? 261.716 257.612 73.194  1.00 82.37  ? 51  ILE C CG1 1 
ATOM 3923 C CG2 . ILE C 1 51  ? 259.336 256.861 73.251  1.00 82.37  ? 51  ILE C CG2 1 
ATOM 3924 C CD1 . ILE C 1 51  ? 261.355 258.979 72.654  1.00 82.37  ? 51  ILE C CD1 1 
ATOM 3925 N N   . ILE C 1 52  ? 258.161 257.726 76.243  1.00 77.06  ? 52  ILE C N   1 
ATOM 3926 C CA  . ILE C 1 52  ? 257.051 257.142 76.982  1.00 77.06  ? 52  ILE C CA  1 
ATOM 3927 C C   . ILE C 1 52  ? 256.366 256.099 76.111  1.00 77.06  ? 52  ILE C C   1 
ATOM 3928 O O   . ILE C 1 52  ? 256.361 256.210 74.885  1.00 77.06  ? 52  ILE C O   1 
ATOM 3929 C CB  . ILE C 1 52  ? 256.043 258.204 77.449  1.00 77.06  ? 52  ILE C CB  1 
ATOM 3930 C CG1 . ILE C 1 52  ? 256.751 259.341 78.186  1.00 77.06  ? 52  ILE C CG1 1 
ATOM 3931 C CG2 . ILE C 1 52  ? 254.984 257.572 78.339  1.00 77.06  ? 52  ILE C CG2 1 
ATOM 3932 C CD1 . ILE C 1 52  ? 256.816 260.630 77.402  1.00 77.06  ? 52  ILE C CD1 1 
ATOM 3933 N N   . ASP C 1 59  ? 255.118 261.808 72.351  1.00 87.30  ? 59  ASP C N   1 
ATOM 3934 C CA  . ASP C 1 59  ? 255.549 262.388 73.617  1.00 87.30  ? 59  ASP C CA  1 
ATOM 3935 C C   . ASP C 1 59  ? 256.944 261.902 74.008  1.00 87.30  ? 59  ASP C C   1 
ATOM 3936 O O   . ASP C 1 59  ? 257.202 260.701 74.059  1.00 87.30  ? 59  ASP C O   1 
ATOM 3937 C CB  . ASP C 1 59  ? 254.541 262.064 74.725  1.00 87.30  ? 59  ASP C CB  1 
ATOM 3938 C CG  . ASP C 1 59  ? 254.106 260.608 74.719  1.00 87.30  ? 59  ASP C CG  1 
ATOM 3939 O OD1 . ASP C 1 59  ? 253.486 260.166 75.710  1.00 87.30  ? 59  ASP C OD1 1 
ATOM 3940 O OD2 . ASP C 1 59  ? 254.382 259.905 73.724  1.00 87.30  ? 59  ASP C OD2 1 
ATOM 3941 N N   . THR C 1 60  ? 257.845 262.848 74.269  1.00 87.21  ? 60  THR C N   1 
ATOM 3942 C CA  . THR C 1 60  ? 259.218 262.556 74.668  1.00 87.21  ? 60  THR C CA  1 
ATOM 3943 C C   . THR C 1 60  ? 259.490 263.225 76.007  1.00 87.21  ? 60  THR C C   1 
ATOM 3944 O O   . THR C 1 60  ? 259.450 264.456 76.106  1.00 87.21  ? 60  THR C O   1 
ATOM 3945 C CB  . THR C 1 60  ? 260.224 263.054 73.626  1.00 87.21  ? 60  THR C CB  1 
ATOM 3946 O OG1 . THR C 1 60  ? 260.142 264.480 73.526  1.00 87.21  ? 60  THR C OG1 1 
ATOM 3947 C CG2 . THR C 1 60  ? 259.951 262.438 72.260  1.00 87.21  ? 60  THR C CG2 1 
ATOM 3948 N N   . MET C 1 61  ? 259.778 262.423 77.027  1.00 87.81  ? 61  MET C N   1 
ATOM 3949 C CA  . MET C 1 61  ? 260.107 262.954 78.348  1.00 87.81  ? 61  MET C CA  1 
ATOM 3950 C C   . MET C 1 61  ? 261.614 263.167 78.408  1.00 87.81  ? 61  MET C C   1 
ATOM 3951 O O   . MET C 1 61  ? 262.385 262.215 78.539  1.00 87.81  ? 61  MET C O   1 
ATOM 3952 C CB  . MET C 1 61  ? 259.628 262.008 79.443  1.00 87.81  ? 61  MET C CB  1 
ATOM 3953 C CG  . MET C 1 61  ? 260.024 262.413 80.851  1.00 87.81  ? 61  MET C CG  1 
ATOM 3954 S SD  . MET C 1 61  ? 259.733 264.156 81.187  1.00 87.81  ? 61  MET C SD  1 
ATOM 3955 C CE  . MET C 1 61  ? 259.590 264.121 82.968  1.00 87.81  ? 61  MET C CE  1 
ATOM 3956 N N   . TYR C 1 62  ? 262.039 264.419 78.303  1.00 87.53  ? 62  TYR C N   1 
ATOM 3957 C CA  . TYR C 1 62  ? 263.453 264.749 78.321  1.00 87.53  ? 62  TYR C CA  1 
ATOM 3958 C C   . TYR C 1 62  ? 263.944 264.951 79.752  1.00 87.53  ? 62  TYR C C   1 
ATOM 3959 O O   . TYR C 1 62  ? 263.166 265.030 80.704  1.00 87.53  ? 62  TYR C O   1 
ATOM 3960 C CB  . TYR C 1 62  ? 263.717 266.004 77.495  1.00 87.53  ? 62  TYR C CB  1 
ATOM 3961 C CG  . TYR C 1 62  ? 264.062 265.737 76.053  1.00 87.53  ? 62  TYR C CG  1 
ATOM 3962 C CD1 . TYR C 1 62  ? 263.116 265.917 75.051  1.00 87.53  ? 62  TYR C CD1 1 
ATOM 3963 C CD2 . TYR C 1 62  ? 265.335 265.316 75.691  1.00 87.53  ? 62  TYR C CD2 1 
ATOM 3964 C CE1 . TYR C 1 62  ? 263.426 265.679 73.728  1.00 87.53  ? 62  TYR C CE1 1 
ATOM 3965 C CE2 . TYR C 1 62  ? 265.656 265.075 74.369  1.00 87.53  ? 62  TYR C CE2 1 
ATOM 3966 C CZ  . TYR C 1 62  ? 264.698 265.262 73.392  1.00 87.53  ? 62  TYR C CZ  1 
ATOM 3967 O OH  . TYR C 1 62  ? 265.010 265.021 72.074  1.00 87.53  ? 62  TYR C OH  1 
ATOM 3968 N N   . TYR C 1 63  ? 265.265 265.038 79.892  1.00 82.79  ? 63  TYR C N   1 
ATOM 3969 C CA  . TYR C 1 63  ? 265.899 265.294 81.186  1.00 82.79  ? 63  TYR C CA  1 
ATOM 3970 C C   . TYR C 1 63  ? 267.156 266.116 80.907  1.00 82.79  ? 63  TYR C C   1 
ATOM 3971 O O   . TYR C 1 63  ? 268.217 265.567 80.607  1.00 82.79  ? 63  TYR C O   1 
ATOM 3972 C CB  . TYR C 1 63  ? 266.226 264.001 81.914  1.00 82.79  ? 63  TYR C CB  1 
ATOM 3973 C CG  . TYR C 1 63  ? 265.106 263.482 82.777  1.00 82.79  ? 63  TYR C CG  1 
ATOM 3974 C CD1 . TYR C 1 63  ? 264.266 262.471 82.325  1.00 82.79  ? 63  TYR C CD1 1 
ATOM 3975 C CD2 . TYR C 1 63  ? 264.893 263.999 84.046  1.00 82.79  ? 63  TYR C CD2 1 
ATOM 3976 C CE1 . TYR C 1 63  ? 263.243 261.993 83.114  1.00 82.79  ? 63  TYR C CE1 1 
ATOM 3977 C CE2 . TYR C 1 63  ? 263.876 263.526 84.841  1.00 82.79  ? 63  TYR C CE2 1 
ATOM 3978 C CZ  . TYR C 1 63  ? 263.053 262.526 84.370  1.00 82.79  ? 63  TYR C CZ  1 
ATOM 3979 O OH  . TYR C 1 63  ? 262.035 262.053 85.162  1.00 82.79  ? 63  TYR C OH  1 
ATOM 3980 N N   . LEU C 1 64  ? 267.022 267.430 81.011  1.00 69.04  ? 64  LEU C N   1 
ATOM 3981 C CA  . LEU C 1 64  ? 268.096 268.347 80.670  1.00 69.04  ? 64  LEU C CA  1 
ATOM 3982 C C   . LEU C 1 64  ? 268.854 268.770 81.921  1.00 69.04  ? 64  LEU C C   1 
ATOM 3983 O O   . LEU C 1 64  ? 268.284 268.853 83.011  1.00 69.04  ? 64  LEU C O   1 
ATOM 3984 C CB  . LEU C 1 64  ? 267.547 269.586 79.959  1.00 69.04  ? 64  LEU C CB  1 
ATOM 3985 C CG  . LEU C 1 64  ? 267.564 269.589 78.429  1.00 69.04  ? 64  LEU C CG  1 
ATOM 3986 C CD1 . LEU C 1 64  ? 267.120 270.940 77.890  1.00 69.04  ? 64  LEU C CD1 1 
ATOM 3987 C CD2 . LEU C 1 64  ? 268.929 269.224 77.897  1.00 69.04  ? 64  LEU C CD2 1 
ATOM 3988 N N   . THR C 1 65  ? 270.149 269.020 81.758  1.00 66.14  ? 65  THR C N   1 
ATOM 3989 C CA  . THR C 1 65  ? 270.938 269.737 82.749  1.00 66.14  ? 65  THR C CA  1 
ATOM 3990 C C   . THR C 1 65  ? 271.777 270.767 82.019  1.00 66.14  ? 65  THR C C   1 
ATOM 3991 O O   . THR C 1 65  ? 272.608 270.413 81.177  1.00 66.14  ? 65  THR C O   1 
ATOM 3992 C CB  . THR C 1 65  ? 271.816 268.800 83.575  1.00 66.14  ? 65  THR C CB  1 
ATOM 3993 O OG1 . THR C 1 65  ? 270.979 267.949 84.364  1.00 66.14  ? 65  THR C OG1 1 
ATOM 3994 C CG2 . THR C 1 65  ? 272.722 269.595 84.489  1.00 66.14  ? 65  THR C CG2 1 
ATOM 3995 N N   . LEU C 1 66  ? 271.550 272.034 82.335  1.00 66.04  ? 66  LEU C N   1 
ATOM 3996 C CA  . LEU C 1 66  ? 272.169 273.138 81.629  1.00 66.04  ? 66  LEU C CA  1 
ATOM 3997 C C   . LEU C 1 66  ? 272.776 274.099 82.636  1.00 66.04  ? 66  LEU C C   1 
ATOM 3998 O O   . LEU C 1 66  ? 272.289 274.238 83.760  1.00 66.04  ? 66  LEU C O   1 
ATOM 3999 C CB  . LEU C 1 66  ? 271.144 273.851 80.734  1.00 66.04  ? 66  LEU C CB  1 
ATOM 4000 C CG  . LEU C 1 66  ? 269.909 274.454 81.414  1.00 66.04  ? 66  LEU C CG  1 
ATOM 4001 C CD1 . LEU C 1 66  ? 270.020 275.971 81.573  1.00 66.04  ? 66  LEU C CD1 1 
ATOM 4002 C CD2 . LEU C 1 66  ? 268.630 274.071 80.687  1.00 66.04  ? 66  LEU C CD2 1 
ATOM 4003 N N   . GLU C 1 67  ? 273.852 274.752 82.222  1.00 74.96  ? 67  GLU C N   1 
ATOM 4004 C CA  . GLU C 1 67  ? 274.498 275.780 83.022  1.00 74.96  ? 67  GLU C CA  1 
ATOM 4005 C C   . GLU C 1 67  ? 274.038 277.150 82.545  1.00 74.96  ? 67  GLU C C   1 
ATOM 4006 O O   . GLU C 1 67  ? 274.151 277.474 81.359  1.00 74.96  ? 67  GLU C O   1 
ATOM 4007 C CB  . GLU C 1 67  ? 276.022 275.643 82.949  1.00 74.96  ? 67  GLU C CB  1 
ATOM 4008 C CG  . GLU C 1 67  ? 276.818 276.880 83.355  1.00 74.96  ? 67  GLU C CG  1 
ATOM 4009 C CD  . GLU C 1 67  ? 277.246 277.704 82.152  1.00 74.96  ? 67  GLU C CD  1 
ATOM 4010 O OE1 . GLU C 1 67  ? 277.818 278.799 82.328  1.00 74.96  ? 67  GLU C OE1 1 
ATOM 4011 O OE2 . GLU C 1 67  ? 277.022 277.228 81.021  1.00 74.96  ? 67  GLU C OE2 1 
ATOM 4012 N N   . ALA C 1 68  ? 273.517 277.947 83.470  1.00 72.95  ? 68  ALA C N   1 
ATOM 4013 C CA  . ALA C 1 68  ? 273.016 279.277 83.158  1.00 72.95  ? 68  ALA C CA  1 
ATOM 4014 C C   . ALA C 1 68  ? 273.822 280.303 83.937  1.00 72.95  ? 68  ALA C C   1 
ATOM 4015 O O   . ALA C 1 68  ? 273.860 280.261 85.171  1.00 72.95  ? 68  ALA C O   1 
ATOM 4016 C CB  . ALA C 1 68  ? 271.529 279.393 83.480  1.00 72.95  ? 68  ALA C CB  1 
ATOM 4017 N N   . LYS C 1 69  ? 274.473 281.206 83.205  1.00 75.48  ? 69  LYS C N   1 
ATOM 4018 C CA  . LYS C 1 69  ? 275.261 282.277 83.799  1.00 75.48  ? 69  LYS C CA  1 
ATOM 4019 C C   . LYS C 1 69  ? 274.358 283.204 84.601  1.00 75.48  ? 69  LYS C C   1 
ATOM 4020 O O   . LYS C 1 69  ? 273.283 283.591 84.139  1.00 75.48  ? 69  LYS C O   1 
ATOM 4021 C CB  . LYS C 1 69  ? 275.981 283.030 82.675  1.00 75.48  ? 69  LYS C CB  1 
ATOM 4022 C CG  . LYS C 1 69  ? 277.139 283.940 83.048  1.00 75.48  ? 69  LYS C CG  1 
ATOM 4023 C CD  . LYS C 1 69  ? 276.700 285.366 83.302  1.00 75.48  ? 69  LYS C CD  1 
ATOM 4024 C CE  . LYS C 1 69  ? 277.870 286.230 83.717  1.00 75.48  ? 69  LYS C CE  1 
ATOM 4025 N NZ  . LYS C 1 69  ? 277.554 287.676 83.572  1.00 75.48  ? 69  LYS C NZ  1 
ATOM 4026 N N   . ASP C 1 70  ? 274.784 283.542 85.818  1.00 69.98  ? 70  ASP C N   1 
ATOM 4027 C CA  . ASP C 1 70  ? 273.960 284.343 86.728  1.00 69.98  ? 70  ASP C CA  1 
ATOM 4028 C C   . ASP C 1 70  ? 274.849 285.327 87.488  1.00 69.98  ? 70  ASP C C   1 
ATOM 4029 O O   . ASP C 1 70  ? 275.414 284.991 88.533  1.00 69.98  ? 70  ASP C O   1 
ATOM 4030 C CB  . ASP C 1 70  ? 273.182 283.445 87.677  1.00 69.98  ? 70  ASP C CB  1 
ATOM 4031 C CG  . ASP C 1 70  ? 272.082 284.184 88.400  1.00 69.98  ? 70  ASP C CG  1 
ATOM 4032 O OD1 . ASP C 1 70  ? 271.710 285.288 87.951  1.00 69.98  ? 70  ASP C OD1 1 
ATOM 4033 O OD2 . ASP C 1 70  ? 271.591 283.658 89.420  1.00 69.98  ? 70  ASP C OD2 1 
ATOM 4034 N N   . GLY C 1 71  ? 274.956 286.545 86.959  1.00 65.63  ? 71  GLY C N   1 
ATOM 4035 C CA  . GLY C 1 71  ? 275.602 287.634 87.665  1.00 65.63  ? 71  GLY C CA  1 
ATOM 4036 C C   . GLY C 1 71  ? 277.098 287.516 87.831  1.00 65.63  ? 71  GLY C C   1 
ATOM 4037 O O   . GLY C 1 71  ? 277.671 288.197 88.684  1.00 65.63  ? 71  GLY C O   1 
ATOM 4038 N N   . GLY C 1 72  ? 277.753 286.672 87.040  1.00 66.95  ? 72  GLY C N   1 
ATOM 4039 C CA  . GLY C 1 72  ? 279.179 286.447 87.151  1.00 66.95  ? 72  GLY C CA  1 
ATOM 4040 C C   . GLY C 1 72  ? 279.552 285.085 87.688  1.00 66.95  ? 72  GLY C C   1 
ATOM 4041 O O   . GLY C 1 72  ? 280.739 284.839 87.938  1.00 66.95  ? 72  GLY C O   1 
ATOM 4042 N N   . LYS C 1 73  ? 278.578 284.199 87.888  1.00 72.02  ? 73  LYS C N   1 
ATOM 4043 C CA  . LYS C 1 73  ? 278.794 282.881 88.473  1.00 72.02  ? 73  LYS C CA  1 
ATOM 4044 C C   . LYS C 1 73  ? 278.141 281.845 87.569  1.00 72.02  ? 73  LYS C C   1 
ATOM 4045 O O   . LYS C 1 73  ? 276.911 281.757 87.508  1.00 72.02  ? 73  LYS C O   1 
ATOM 4046 C CB  . LYS C 1 73  ? 278.218 282.791 89.890  1.00 72.02  ? 73  LYS C CB  1 
ATOM 4047 C CG  . LYS C 1 73  ? 279.073 283.381 91.016  1.00 72.02  ? 73  LYS C CG  1 
ATOM 4048 C CD  . LYS C 1 73  ? 278.988 284.896 91.115  1.00 72.02  ? 73  LYS C CD  1 
ATOM 4049 C CE  . LYS C 1 73  ? 277.560 285.357 91.347  1.00 72.02  ? 73  LYS C CE  1 
ATOM 4050 N NZ  . LYS C 1 73  ? 277.507 286.758 91.849  1.00 72.02  ? 73  LYS C NZ  1 
ATOM 4051 N N   . LYS C 1 74  ? 278.959 281.062 86.872  1.00 73.41  ? 74  LYS C N   1 
ATOM 4052 C CA  . LYS C 1 74  ? 278.447 279.977 86.043  1.00 73.41  ? 74  LYS C CA  1 
ATOM 4053 C C   . LYS C 1 74  ? 278.034 278.812 86.934  1.00 73.41  ? 74  LYS C C   1 
ATOM 4054 O O   . LYS C 1 74  ? 278.879 278.171 87.565  1.00 73.41  ? 74  LYS C O   1 
ATOM 4055 C CB  . LYS C 1 74  ? 279.501 279.542 85.032  1.00 73.41  ? 74  LYS C CB  1 
ATOM 4056 C CG  . LYS C 1 74  ? 280.150 280.678 84.266  1.00 73.41  ? 74  LYS C CG  1 
ATOM 4057 C CD  . LYS C 1 74  ? 280.800 280.173 82.984  1.00 73.41  ? 74  LYS C CD  1 
ATOM 4058 C CE  . LYS C 1 74  ? 281.776 279.036 83.253  1.00 73.41  ? 74  LYS C CE  1 
ATOM 4059 N NZ  . LYS C 1 74  ? 282.266 278.402 82.000  1.00 73.41  ? 74  LYS C NZ  1 
ATOM 4060 N N   . LYS C 1 75  ? 276.737 278.527 86.988  1.00 65.22  ? 75  LYS C N   1 
ATOM 4061 C CA  . LYS C 1 75  ? 276.209 277.498 87.867  1.00 65.22  ? 75  LYS C CA  1 
ATOM 4062 C C   . LYS C 1 75  ? 275.297 276.564 87.086  1.00 65.22  ? 75  LYS C C   1 
ATOM 4063 O O   . LYS C 1 75  ? 274.560 277.001 86.199  1.00 65.22  ? 75  LYS C O   1 
ATOM 4064 C CB  . LYS C 1 75  ? 275.465 278.139 89.070  1.00 65.22  ? 75  LYS C CB  1 
ATOM 4065 C CG  . LYS C 1 75  ? 274.720 277.183 90.022  1.00 65.22  ? 75  LYS C CG  1 
ATOM 4066 C CD  . LYS C 1 75  ? 275.588 276.122 90.737  1.00 65.22  ? 75  LYS C CD  1 
ATOM 4067 C CE  . LYS C 1 75  ? 276.922 276.642 91.291  1.00 65.22  ? 75  LYS C CE  1 
ATOM 4068 N NZ  . LYS C 1 75  ? 277.623 275.606 92.093  1.00 65.22  ? 75  LYS C NZ  1 
ATOM 4069 N N   . LEU C 1 76  ? 275.373 275.275 87.409  1.00 61.34  ? 76  LEU C N   1 
ATOM 4070 C CA  . LEU C 1 76  ? 274.601 274.248 86.729  1.00 61.34  ? 76  LEU C CA  1 
ATOM 4071 C C   . LEU C 1 76  ? 273.174 274.204 87.262  1.00 61.34  ? 76  LEU C C   1 
ATOM 4072 O O   . LEU C 1 76  ? 272.899 274.605 88.396  1.00 61.34  ? 76  LEU C O   1 
ATOM 4073 C CB  . LEU C 1 76  ? 275.257 272.874 86.900  1.00 61.34  ? 76  LEU C CB  1 
ATOM 4074 C CG  . LEU C 1 76  ? 276.393 272.405 85.982  1.00 61.34  ? 76  LEU C CG  1 
ATOM 4075 C CD1 . LEU C 1 76  ? 275.883 272.272 84.561  1.00 61.34  ? 76  LEU C CD1 1 
ATOM 4076 C CD2 . LEU C 1 76  ? 277.644 273.278 86.032  1.00 61.34  ? 76  LEU C CD2 1 
ATOM 4077 N N   . TYR C 1 77  ? 272.262 273.710 86.424  1.00 60.18  ? 77  TYR C N   1 
ATOM 4078 C CA  . TYR C 1 77  ? 270.840 273.675 86.747  1.00 60.18  ? 77  TYR C CA  1 
ATOM 4079 C C   . TYR C 1 77  ? 270.205 272.465 86.085  1.00 60.18  ? 77  TYR C C   1 
ATOM 4080 O O   . TYR C 1 77  ? 270.327 272.291 84.869  1.00 60.18  ? 77  TYR C O   1 
ATOM 4081 C CB  . TYR C 1 77  ? 270.135 274.951 86.278  1.00 60.18  ? 77  TYR C CB  1 
ATOM 4082 C CG  . TYR C 1 77  ? 270.424 276.156 87.131  1.00 60.18  ? 77  TYR C CG  1 
ATOM 4083 C CD1 . TYR C 1 77  ? 271.373 277.090 86.742  1.00 60.18  ? 77  TYR C CD1 1 
ATOM 4084 C CD2 . TYR C 1 77  ? 269.747 276.362 88.323  1.00 60.18  ? 77  TYR C CD2 1 
ATOM 4085 C CE1 . TYR C 1 77  ? 271.651 278.191 87.522  1.00 60.18  ? 77  TYR C CE1 1 
ATOM 4086 C CE2 . TYR C 1 77  ? 270.011 277.467 89.108  1.00 60.18  ? 77  TYR C CE2 1 
ATOM 4087 C CZ  . TYR C 1 77  ? 270.961 278.378 88.700  1.00 60.18  ? 77  TYR C CZ  1 
ATOM 4088 O OH  . TYR C 1 77  ? 271.229 279.476 89.480  1.00 60.18  ? 77  TYR C OH  1 
ATOM 4089 N N   . GLU C 1 78  ? 269.521 271.648 86.878  1.00 63.04  ? 78  GLU C N   1 
ATOM 4090 C CA  . GLU C 1 78  ? 268.803 270.490 86.364  1.00 63.04  ? 78  GLU C CA  1 
ATOM 4091 C C   . GLU C 1 78  ? 267.434 270.923 85.865  1.00 63.04  ? 78  GLU C C   1 
ATOM 4092 O O   . GLU C 1 78  ? 266.813 271.822 86.435  1.00 63.04  ? 78  GLU C O   1 
ATOM 4093 C CB  . GLU C 1 78  ? 268.658 269.421 87.448  1.00 63.04  ? 78  GLU C CB  1 
ATOM 4094 C CG  . GLU C 1 78  ? 268.273 268.042 86.930  1.00 63.04  ? 78  GLU C CG  1 
ATOM 4095 C CD  . GLU C 1 78  ? 266.832 267.677 87.236  1.00 63.04  ? 78  GLU C CD  1 
ATOM 4096 O OE1 . GLU C 1 78  ? 266.247 268.282 88.158  1.00 63.04  ? 78  GLU C OE1 1 
ATOM 4097 O OE2 . GLU C 1 78  ? 266.285 266.783 86.557  1.00 63.04  ? 78  GLU C OE2 1 
ATOM 4098 N N   . ALA C 1 79  ? 266.969 270.286 84.793  1.00 64.15  ? 79  ALA C N   1 
ATOM 4099 C CA  . ALA C 1 79  ? 265.689 270.628 84.192  1.00 64.15  ? 79  ALA C CA  1 
ATOM 4100 C C   . ALA C 1 79  ? 264.928 269.360 83.839  1.00 64.15  ? 79  ALA C C   1 
ATOM 4101 O O   . ALA C 1 79  ? 265.523 268.325 83.533  1.00 64.15  ? 79  ALA C O   1 
ATOM 4102 C CB  . ALA C 1 79  ? 265.870 271.491 82.938  1.00 64.15  ? 79  ALA C CB  1 
ATOM 4103 N N   . LYS C 1 80  ? 263.601 269.443 83.896  1.00 71.42  ? 80  LYS C N   1 
ATOM 4104 C CA  . LYS C 1 80  ? 262.721 268.377 83.418  1.00 71.42  ? 80  LYS C CA  1 
ATOM 4105 C C   . LYS C 1 80  ? 261.682 268.999 82.492  1.00 71.42  ? 80  LYS C C   1 
ATOM 4106 O O   . LYS C 1 80  ? 260.722 269.621 82.955  1.00 71.42  ? 80  LYS C O   1 
ATOM 4107 C CB  . LYS C 1 80  ? 262.044 267.630 84.566  1.00 71.42  ? 80  LYS C CB  1 
ATOM 4108 C CG  . LYS C 1 80  ? 262.971 267.090 85.645  1.00 71.42  ? 80  LYS C CG  1 
ATOM 4109 C CD  . LYS C 1 80  ? 262.230 266.752 86.941  1.00 71.42  ? 80  LYS C CD  1 
ATOM 4110 C CE  . LYS C 1 80  ? 260.910 266.032 86.721  1.00 71.42  ? 80  LYS C CE  1 
ATOM 4111 N NZ  . LYS C 1 80  ? 261.059 264.756 85.976  1.00 71.42  ? 80  LYS C NZ  1 
ATOM 4112 N N   . VAL C 1 81  ? 261.869 268.832 81.189  1.00 75.98  ? 81  VAL C N   1 
ATOM 4113 C CA  . VAL C 1 81  ? 260.875 269.243 80.208  1.00 75.98  ? 81  VAL C CA  1 
ATOM 4114 C C   . VAL C 1 81  ? 260.241 267.990 79.622  1.00 75.98  ? 81  VAL C C   1 
ATOM 4115 O O   . VAL C 1 81  ? 260.818 266.897 79.657  1.00 75.98  ? 81  VAL C O   1 
ATOM 4116 C CB  . VAL C 1 81  ? 261.469 270.140 79.096  1.00 75.98  ? 81  VAL C CB  1 
ATOM 4117 C CG1 . VAL C 1 81  ? 262.227 271.298 79.697  1.00 75.98  ? 81  VAL C CG1 1 
ATOM 4118 C CG2 . VAL C 1 81  ? 262.382 269.355 78.192  1.00 75.98  ? 81  VAL C CG2 1 
ATOM 4119 N N   . TRP C 1 82  ? 259.022 268.148 79.116  1.00 88.70  ? 82  TRP C N   1 
ATOM 4120 C CA  . TRP C 1 82  ? 258.296 267.067 78.462  1.00 88.70  ? 82  TRP C CA  1 
ATOM 4121 C C   . TRP C 1 82  ? 257.735 267.595 77.155  1.00 88.70  ? 82  TRP C C   1 
ATOM 4122 O O   . TRP C 1 82  ? 256.974 268.567 77.155  1.00 88.70  ? 82  TRP C O   1 
ATOM 4123 C CB  . TRP C 1 82  ? 257.168 266.527 79.342  1.00 88.70  ? 82  TRP C CB  1 
ATOM 4124 C CG  . TRP C 1 82  ? 256.124 265.808 78.552  1.00 88.70  ? 82  TRP C CG  1 
ATOM 4125 C CD1 . TRP C 1 82  ? 256.216 264.552 78.029  1.00 88.70  ? 82  TRP C CD1 1 
ATOM 4126 C CD2 . TRP C 1 82  ? 254.834 266.304 78.180  1.00 88.70  ? 82  TRP C CD2 1 
ATOM 4127 N NE1 . TRP C 1 82  ? 255.062 264.233 77.357  1.00 88.70  ? 82  TRP C NE1 1 
ATOM 4128 C CE2 . TRP C 1 82  ? 254.198 265.293 77.434  1.00 88.70  ? 82  TRP C CE2 1 
ATOM 4129 C CE3 . TRP C 1 82  ? 254.155 267.505 78.405  1.00 88.70  ? 82  TRP C CE3 1 
ATOM 4130 C CZ2 . TRP C 1 82  ? 252.915 265.445 76.914  1.00 88.70  ? 82  TRP C CZ2 1 
ATOM 4131 C CZ3 . TRP C 1 82  ? 252.883 267.654 77.889  1.00 88.70  ? 82  TRP C CZ3 1 
ATOM 4132 C CH2 . TRP C 1 82  ? 252.276 266.631 77.153  1.00 88.70  ? 82  TRP C CH2 1 
ATOM 4133 N N   . VAL C 1 83  ? 258.096 266.952 76.053  1.00 85.08  ? 83  VAL C N   1 
ATOM 4134 C CA  . VAL C 1 83  ? 257.670 267.422 74.747  1.00 85.08  ? 83  VAL C CA  1 
ATOM 4135 C C   . VAL C 1 83  ? 257.482 266.258 73.787  1.00 85.08  ? 83  VAL C C   1 
ATOM 4136 O O   . VAL C 1 83  ? 256.378 265.730 73.652  1.00 85.08  ? 83  VAL C O   1 
ATOM 4137 C CB  . VAL C 1 83  ? 258.671 268.440 74.187  1.00 85.08  ? 83  VAL C CB  1 
ATOM 4138 C CG1 . VAL C 1 83  ? 260.004 267.775 73.905  1.00 85.08  ? 83  VAL C CG1 1 
ATOM 4139 C CG2 . VAL C 1 83  ? 258.117 269.090 72.944  1.00 85.08  ? 83  VAL C CG2 1 
ATOM 4140 N N   . GLY C 1 89  ? 260.376 267.316 63.515  1.00 69.93  ? 89  GLY C N   1 
ATOM 4141 C CA  . GLY C 1 89  ? 259.036 267.001 63.057  1.00 69.93  ? 89  GLY C CA  1 
ATOM 4142 C C   . GLY C 1 89  ? 258.032 266.887 64.187  1.00 69.93  ? 89  GLY C C   1 
ATOM 4143 O O   . GLY C 1 89  ? 257.408 267.873 64.573  1.00 69.93  ? 89  GLY C O   1 
ATOM 4144 N N   . LEU C 1 90  ? 257.878 265.671 64.719  1.00 75.90  ? 90  LEU C N   1 
ATOM 4145 C CA  . LEU C 1 90  ? 256.961 265.443 65.831  1.00 75.90  ? 90  LEU C CA  1 
ATOM 4146 C C   . LEU C 1 90  ? 257.504 266.001 67.141  1.00 75.90  ? 90  LEU C C   1 
ATOM 4147 O O   . LEU C 1 90  ? 256.719 266.275 68.057  1.00 75.90  ? 90  LEU C O   1 
ATOM 4148 C CB  . LEU C 1 90  ? 256.660 263.937 65.941  1.00 75.90  ? 90  LEU C CB  1 
ATOM 4149 C CG  . LEU C 1 90  ? 255.842 263.276 67.065  1.00 75.90  ? 90  LEU C CG  1 
ATOM 4150 C CD1 . LEU C 1 90  ? 255.046 262.108 66.506  1.00 75.90  ? 90  LEU C CD1 1 
ATOM 4151 C CD2 . LEU C 1 90  ? 256.720 262.781 68.214  1.00 75.90  ? 90  LEU C CD2 1 
ATOM 4152 N N   . ASN C 1 91  ? 258.821 266.196 67.241  1.00 77.52  ? 91  ASN C N   1 
ATOM 4153 C CA  . ASN C 1 91  ? 259.420 266.661 68.489  1.00 77.52  ? 91  ASN C CA  1 
ATOM 4154 C C   . ASN C 1 91  ? 259.096 268.129 68.747  1.00 77.52  ? 91  ASN C C   1 
ATOM 4155 O O   . ASN C 1 91  ? 258.451 268.467 69.745  1.00 77.52  ? 91  ASN C O   1 
ATOM 4156 C CB  . ASN C 1 91  ? 260.934 266.436 68.458  1.00 77.52  ? 91  ASN C CB  1 
ATOM 4157 C CG  . ASN C 1 91  ? 261.536 266.323 69.848  1.00 77.52  ? 91  ASN C CG  1 
ATOM 4158 O OD1 . ASN C 1 91  ? 262.462 267.055 70.198  1.00 77.52  ? 91  ASN C OD1 1 
ATOM 4159 N ND2 . ASN C 1 91  ? 261.010 265.403 70.647  1.00 77.52  ? 91  ASN C ND2 1 
ATOM 4160 N N   . LYS C 1 92  ? 259.523 269.019 67.848  1.00 78.90  ? 92  LYS C N   1 
ATOM 4161 C CA  . LYS C 1 92  ? 259.360 270.449 68.094  1.00 78.90  ? 92  LYS C CA  1 
ATOM 4162 C C   . LYS C 1 92  ? 257.925 270.918 67.893  1.00 78.90  ? 92  LYS C C   1 
ATOM 4163 O O   . LYS C 1 92  ? 257.528 271.937 68.467  1.00 78.90  ? 92  LYS C O   1 
ATOM 4164 C CB  . LYS C 1 92  ? 260.309 271.251 67.201  1.00 78.90  ? 92  LYS C CB  1 
ATOM 4165 C CG  . LYS C 1 92  ? 261.734 271.346 67.738  1.00 78.90  ? 92  LYS C CG  1 
ATOM 4166 C CD  . LYS C 1 92  ? 261.760 271.669 69.228  1.00 78.90  ? 92  LYS C CD  1 
ATOM 4167 C CE  . LYS C 1 92  ? 263.173 271.643 69.777  1.00 78.90  ? 92  LYS C CE  1 
ATOM 4168 N NZ  . LYS C 1 92  ? 263.372 272.634 70.867  1.00 78.90  ? 92  LYS C NZ  1 
ATOM 4169 N N   . TYR C 1 93  ? 257.135 270.198 67.097  1.00 93.20  ? 93  TYR C N   1 
ATOM 4170 C CA  . TYR C 1 93  ? 255.717 270.520 66.927  1.00 93.20  ? 93  TYR C CA  1 
ATOM 4171 C C   . TYR C 1 93  ? 254.901 269.763 67.976  1.00 93.20  ? 93  TYR C C   1 
ATOM 4172 O O   . TYR C 1 93  ? 254.114 268.861 67.684  1.00 93.20  ? 93  TYR C O   1 
ATOM 4173 C CB  . TYR C 1 93  ? 255.260 270.198 65.511  1.00 93.20  ? 93  TYR C CB  1 
ATOM 4174 C CG  . TYR C 1 93  ? 255.697 271.218 64.484  1.00 93.20  ? 93  TYR C CG  1 
ATOM 4175 C CD1 . TYR C 1 93  ? 256.656 270.905 63.527  1.00 93.20  ? 93  TYR C CD1 1 
ATOM 4176 C CD2 . TYR C 1 93  ? 255.151 272.497 64.473  1.00 93.20  ? 93  TYR C CD2 1 
ATOM 4177 C CE1 . TYR C 1 93  ? 257.057 271.837 62.586  1.00 93.20  ? 93  TYR C CE1 1 
ATOM 4178 C CE2 . TYR C 1 93  ? 255.546 273.437 63.537  1.00 93.20  ? 93  TYR C CE2 1 
ATOM 4179 C CZ  . TYR C 1 93  ? 256.499 273.101 62.597  1.00 93.20  ? 93  TYR C CZ  1 
ATOM 4180 O OH  . TYR C 1 93  ? 256.893 274.033 61.665  1.00 93.20  ? 93  TYR C OH  1 
ATOM 4181 N N   . ASN C 1 94  ? 255.111 270.159 69.229  1.00 87.31  ? 94  ASN C N   1 
ATOM 4182 C CA  . ASN C 1 94  ? 254.464 269.519 70.364  1.00 87.31  ? 94  ASN C CA  1 
ATOM 4183 C C   . ASN C 1 94  ? 254.417 270.518 71.511  1.00 87.31  ? 94  ASN C C   1 
ATOM 4184 O O   . ASN C 1 94  ? 255.105 271.542 71.495  1.00 87.31  ? 94  ASN C O   1 
ATOM 4185 C CB  . ASN C 1 94  ? 255.201 268.239 70.779  1.00 87.31  ? 94  ASN C CB  1 
ATOM 4186 C CG  . ASN C 1 94  ? 254.298 267.243 71.480  1.00 87.31  ? 94  ASN C CG  1 
ATOM 4187 O OD1 . ASN C 1 94  ? 253.366 267.622 72.188  1.00 87.31  ? 94  ASN C OD1 1 
ATOM 4188 N ND2 . ASN C 1 94  ? 254.576 265.959 71.290  1.00 87.31  ? 94  ASN C ND2 1 
ATOM 4189 N N   . PHE C 1 95  ? 253.586 270.209 72.502  1.00 88.35  ? 95  PHE C N   1 
ATOM 4190 C CA  . PHE C 1 95  ? 253.421 271.064 73.675  1.00 88.35  ? 95  PHE C CA  1 
ATOM 4191 C C   . PHE C 1 95  ? 254.566 270.790 74.644  1.00 88.35  ? 95  PHE C C   1 
ATOM 4192 O O   . PHE C 1 95  ? 254.544 269.814 75.396  1.00 88.35  ? 95  PHE C O   1 
ATOM 4193 C CB  . PHE C 1 95  ? 252.058 270.823 74.318  1.00 88.35  ? 95  PHE C CB  1 
ATOM 4194 C CG  . PHE C 1 95  ? 251.845 271.572 75.605  1.00 88.35  ? 95  PHE C CG  1 
ATOM 4195 C CD1 . PHE C 1 95  ? 251.904 270.915 76.826  1.00 88.35  ? 95  PHE C CD1 1 
ATOM 4196 C CD2 . PHE C 1 95  ? 251.585 272.933 75.594  1.00 88.35  ? 95  PHE C CD2 1 
ATOM 4197 C CE1 . PHE C 1 95  ? 251.704 271.601 78.012  1.00 88.35  ? 95  PHE C CE1 1 
ATOM 4198 C CE2 . PHE C 1 95  ? 251.386 273.626 76.777  1.00 88.35  ? 95  PHE C CE2 1 
ATOM 4199 C CZ  . PHE C 1 95  ? 251.447 272.958 77.986  1.00 88.35  ? 95  PHE C CZ  1 
ATOM 4200 N N   . LYS C 1 96  ? 255.582 271.647 74.613  1.00 84.60  ? 96  LYS C N   1 
ATOM 4201 C CA  . LYS C 1 96  ? 256.686 271.580 75.559  1.00 84.60  ? 96  LYS C CA  1 
ATOM 4202 C C   . LYS C 1 96  ? 256.301 272.307 76.839  1.00 84.60  ? 96  LYS C C   1 
ATOM 4203 O O   . LYS C 1 96  ? 255.621 273.336 76.798  1.00 84.60  ? 96  LYS C O   1 
ATOM 4204 C CB  . LYS C 1 96  ? 257.945 272.204 74.956  1.00 84.60  ? 96  LYS C CB  1 
ATOM 4205 C CG  . LYS C 1 96  ? 257.683 273.498 74.205  1.00 84.60  ? 96  LYS C CG  1 
ATOM 4206 C CD  . LYS C 1 96  ? 258.625 273.667 73.026  1.00 84.60  ? 96  LYS C CD  1 
ATOM 4207 C CE  . LYS C 1 96  ? 260.074 273.696 73.474  1.00 84.60  ? 96  LYS C CE  1 
ATOM 4208 N NZ  . LYS C 1 96  ? 260.999 273.948 72.337  1.00 84.60  ? 96  LYS C NZ  1 
ATOM 4209 N N   . GLU C 1 97  ? 256.744 271.776 77.977  1.00 78.27  ? 97  GLU C N   1 
ATOM 4210 C CA  . GLU C 1 97  ? 256.341 272.335 79.260  1.00 78.27  ? 97  GLU C CA  1 
ATOM 4211 C C   . GLU C 1 97  ? 257.374 271.973 80.318  1.00 78.27  ? 97  GLU C C   1 
ATOM 4212 O O   . GLU C 1 97  ? 257.809 270.821 80.395  1.00 78.27  ? 97  GLU C O   1 
ATOM 4213 C CB  . GLU C 1 97  ? 254.944 271.826 79.638  1.00 78.27  ? 97  GLU C CB  1 
ATOM 4214 C CG  . GLU C 1 97  ? 254.438 272.213 81.008  1.00 78.27  ? 97  GLU C CG  1 
ATOM 4215 C CD  . GLU C 1 97  ? 254.588 271.097 82.016  1.00 78.27  ? 97  GLU C CD  1 
ATOM 4216 O OE1 . GLU C 1 97  ? 255.080 271.363 83.127  1.00 78.27  ? 97  GLU C OE1 1 
ATOM 4217 O OE2 . GLU C 1 97  ? 254.215 269.950 81.695  1.00 78.27  ? 97  GLU C OE2 1 
ATOM 4218 N N   . LEU C 1 98  ? 257.762 272.962 81.122  1.00 75.25  ? 98  LEU C N   1 
ATOM 4219 C CA  . LEU C 1 98  ? 258.789 272.797 82.144  1.00 75.25  ? 98  LEU C CA  1 
ATOM 4220 C C   . LEU C 1 98  ? 258.169 272.417 83.482  1.00 75.25  ? 98  LEU C C   1 
ATOM 4221 O O   . LEU C 1 98  ? 257.229 273.071 83.944  1.00 75.25  ? 98  LEU C O   1 
ATOM 4222 C CB  . LEU C 1 98  ? 259.589 274.087 82.305  1.00 75.25  ? 98  LEU C CB  1 
ATOM 4223 C CG  . LEU C 1 98  ? 260.790 274.052 83.250  1.00 75.25  ? 98  LEU C CG  1 
ATOM 4224 C CD1 . LEU C 1 98  ? 261.669 272.842 83.021  1.00 75.25  ? 98  LEU C CD1 1 
ATOM 4225 C CD2 . LEU C 1 98  ? 261.586 275.315 83.117  1.00 75.25  ? 98  LEU C CD2 1 
ATOM 4226 N N   . GLN C 1 99  ? 258.732 271.392 84.124  1.00 77.72  ? 99  GLN C N   1 
ATOM 4227 C CA  . GLN C 1 99  ? 258.246 270.935 85.417  1.00 77.72  ? 99  GLN C CA  1 
ATOM 4228 C C   . GLN C 1 99  ? 259.177 271.243 86.579  1.00 77.72  ? 99  GLN C C   1 
ATOM 4229 O O   . GLN C 1 99  ? 258.698 271.349 87.711  1.00 77.72  ? 99  GLN C O   1 
ATOM 4230 C CB  . GLN C 1 99  ? 257.990 269.420 85.391  1.00 77.72  ? 99  GLN C CB  1 
ATOM 4231 C CG  . GLN C 1 99  ? 256.890 268.983 84.443  1.00 77.72  ? 99  GLN C CG  1 
ATOM 4232 C CD  . GLN C 1 99  ? 257.420 268.323 83.187  1.00 77.72  ? 99  GLN C CD  1 
ATOM 4233 O OE1 . GLN C 1 99  ? 258.481 267.704 83.198  1.00 77.72  ? 99  GLN C OE1 1 
ATOM 4234 N NE2 . GLN C 1 99  ? 256.678 268.450 82.096  1.00 77.72  ? 99  GLN C NE2 1 
ATOM 4235 N N   . GLU C 1 100 ? 260.477 271.395 86.342  1.00 74.60  ? 100 GLU C N   1 
ATOM 4236 C CA  . GLU C 1 100 ? 261.411 271.546 87.447  1.00 74.60  ? 100 GLU C CA  1 
ATOM 4237 C C   . GLU C 1 100 ? 262.668 272.251 86.965  1.00 74.60  ? 100 GLU C C   1 
ATOM 4238 O O   . GLU C 1 100 ? 263.167 271.961 85.878  1.00 74.60  ? 100 GLU C O   1 
ATOM 4239 C CB  . GLU C 1 100 ? 261.765 270.180 88.046  1.00 74.60  ? 100 GLU C CB  1 
ATOM 4240 C CG  . GLU C 1 100 ? 262.695 270.210 89.248  1.00 74.60  ? 100 GLU C CG  1 
ATOM 4241 C CD  . GLU C 1 100 ? 261.990 270.631 90.520  1.00 74.60  ? 100 GLU C CD  1 
ATOM 4242 O OE1 . GLU C 1 100 ? 261.576 269.742 91.289  1.00 74.60  ? 100 GLU C OE1 1 
ATOM 4243 O OE2 . GLU C 1 100 ? 261.860 271.851 90.750  1.00 74.60  ? 100 GLU C OE2 1 
ATOM 4244 N N   . PHE C 1 101 ? 263.168 273.178 87.776  1.00 67.80  ? 101 PHE C N   1 
ATOM 4245 C CA  . PHE C 1 101 ? 264.423 273.862 87.495  1.00 67.80  ? 101 PHE C CA  1 
ATOM 4246 C C   . PHE C 1 101 ? 265.252 273.979 88.765  1.00 67.80  ? 101 PHE C C   1 
ATOM 4247 O O   . PHE C 1 101 ? 265.795 275.043 89.075  1.00 67.80  ? 101 PHE C O   1 
ATOM 4248 C CB  . PHE C 1 101 ? 264.176 275.238 86.880  1.00 67.80  ? 101 PHE C CB  1 
ATOM 4249 C CG  . PHE C 1 101 ? 265.267 275.696 85.956  1.00 67.80  ? 101 PHE C CG  1 
ATOM 4250 C CD1 . PHE C 1 101 ? 265.331 275.215 84.663  1.00 67.80  ? 101 PHE C CD1 1 
ATOM 4251 C CD2 . PHE C 1 101 ? 266.215 276.614 86.373  1.00 67.80  ? 101 PHE C CD2 1 
ATOM 4252 C CE1 . PHE C 1 101 ? 266.322 275.635 83.804  1.00 67.80  ? 101 PHE C CE1 1 
ATOM 4253 C CE2 . PHE C 1 101 ? 267.209 277.037 85.520  1.00 67.80  ? 101 PHE C CE2 1 
ATOM 4254 C CZ  . PHE C 1 101 ? 267.263 276.547 84.234  1.00 67.80  ? 101 PHE C CZ  1 
ATOM 4255 N N   . LYS C 1 102 ? 265.345 272.897 89.532  1.00 57.46  ? 102 LYS C N   1 
ATOM 4256 C CA  . LYS C 1 102 ? 266.115 273.028 90.756  1.00 57.46  ? 102 LYS C CA  1 
ATOM 4257 C C   . LYS C 1 102 ? 267.607 272.855 90.472  1.00 57.46  ? 102 LYS C C   1 
ATOM 4258 O O   . LYS C 1 102 ? 267.996 272.095 89.581  1.00 57.46  ? 102 LYS C O   1 
ATOM 4259 C CB  . LYS C 1 102 ? 265.642 272.025 91.810  1.00 57.46  ? 102 LYS C CB  1 
ATOM 4260 C CG  . LYS C 1 102 ? 265.964 270.565 91.562  1.00 57.46  ? 102 LYS C CG  1 
ATOM 4261 C CD  . LYS C 1 102 ? 265.281 269.684 92.594  1.00 57.46  ? 102 LYS C CD  1 
ATOM 4262 C CE  . LYS C 1 102 ? 265.921 268.311 92.663  1.00 57.46  ? 102 LYS C CE  1 
ATOM 4263 N NZ  . LYS C 1 102 ? 267.410 268.379 92.638  1.00 57.46  ? 102 LYS C NZ  1 
ATOM 4264 N N   . PRO C 1 103 ? 268.462 273.599 91.178  1.00 49.49  ? 103 PRO C N   1 
ATOM 4265 C CA  . PRO C 1 103 ? 269.905 273.488 90.934  1.00 49.49  ? 103 PRO C CA  1 
ATOM 4266 C C   . PRO C 1 103 ? 270.528 272.260 91.578  1.00 49.49  ? 103 PRO C C   1 
ATOM 4267 O O   . PRO C 1 103 ? 269.828 271.413 92.139  1.00 49.49  ? 103 PRO C O   1 
ATOM 4268 C CB  . PRO C 1 103 ? 270.458 274.778 91.547  1.00 49.49  ? 103 PRO C CB  1 
ATOM 4269 C CG  . PRO C 1 103 ? 269.479 275.125 92.608  1.00 49.49  ? 103 PRO C CG  1 
ATOM 4270 C CD  . PRO C 1 103 ? 268.143 274.721 92.079  1.00 49.49  ? 103 PRO C CD  1 
ATOM 4271 N N   . VAL C 1 104 ? 271.852 272.160 91.504  1.00 50.94  ? 104 VAL C N   1 
ATOM 4272 C CA  . VAL C 1 104 ? 272.596 271.028 92.039  1.00 50.94  ? 104 VAL C CA  1 
ATOM 4273 C C   . VAL C 1 104 ? 273.353 271.488 93.279  1.00 50.94  ? 104 VAL C C   1 
ATOM 4274 O O   . VAL C 1 104 ? 273.973 272.559 93.278  1.00 50.94  ? 104 VAL C O   1 
ATOM 4275 C CB  . VAL C 1 104 ? 273.536 270.431 90.978  1.00 50.94  ? 104 VAL C CB  1 
ATOM 4276 C CG1 . VAL C 1 104 ? 272.743 269.579 90.007  1.00 50.94  ? 104 VAL C CG1 1 
ATOM 4277 C CG2 . VAL C 1 104 ? 274.248 271.531 90.210  1.00 50.94  ? 104 VAL C CG2 1 
ATOM 4278 N N   . GLY C 1 105 ? 273.258 270.703 94.354  1.00 43.52  ? 105 GLY C N   1 
ATOM 4279 C CA  . GLY C 1 105 ? 273.891 271.048 95.614  1.00 43.52  ? 105 GLY C CA  1 
ATOM 4280 C C   . GLY C 1 105 ? 273.089 272.063 96.402  1.00 43.52  ? 105 GLY C C   1 
ATOM 4281 O O   . GLY C 1 105 ? 272.702 273.101 95.858  1.00 43.52  ? 105 GLY C O   1 
ATOM 4282 N N   . ASP C 1 106 ? 272.847 271.804 97.683  1.00 47.00  ? 106 ASP C N   1 
ATOM 4283 C CA  . ASP C 1 106 ? 271.953 272.645 98.470  1.00 47.00  ? 106 ASP C CA  1 
ATOM 4284 C C   . ASP C 1 106 ? 272.653 273.885 99.022  1.00 47.00  ? 106 ASP C C   1 
ATOM 4285 O O   . ASP C 1 106 ? 271.988 274.779 99.556  1.00 47.00  ? 106 ASP C O   1 
ATOM 4286 C CB  . ASP C 1 106 ? 271.327 271.818 99.602  1.00 47.00  ? 106 ASP C CB  1 
ATOM 4287 C CG  . ASP C 1 106 ? 270.161 272.523 100.284 1.00 47.00  ? 106 ASP C CG  1 
ATOM 4288 O OD1 . ASP C 1 106 ? 270.385 273.184 101.319 1.00 47.00  ? 106 ASP C OD1 1 
ATOM 4289 O OD2 . ASP C 1 106 ? 269.026 272.431 99.774  1.00 47.00  ? 106 ASP C OD2 1 
ATOM 4290 N N   . ALA C 1 107 ? 273.969 273.996 98.840  1.00 53.19  ? 107 ALA C N   1 
ATOM 4291 C CA  . ALA C 1 107 ? 274.738 275.086 99.440  1.00 53.19  ? 107 ALA C CA  1 
ATOM 4292 C C   . ALA C 1 107 ? 274.435 276.392 98.707  1.00 53.19  ? 107 ALA C C   1 
ATOM 4293 O O   . ALA C 1 107 ? 275.161 276.839 97.817  1.00 53.19  ? 107 ALA C O   1 
ATOM 4294 C CB  . ALA C 1 107 ? 276.226 274.769 99.423  1.00 53.19  ? 107 ALA C CB  1 
ATOM 4295 N N   . GLY C 1 108 ? 273.306 276.991 99.082  1.00 52.04  ? 108 GLY C N   1 
ATOM 4296 C CA  . GLY C 1 108 ? 273.019 278.383 98.818  1.00 52.04  ? 108 GLY C CA  1 
ATOM 4297 C C   . GLY C 1 108 ? 273.072 279.237 100.063 1.00 52.04  ? 108 GLY C C   1 
ATOM 4298 O O   . GLY C 1 108 ? 272.561 280.365 100.044 1.00 52.04  ? 108 GLY C O   1 
ATOM 4299 N N   . GLY C 1 109 ? 273.664 278.745 101.149 1.00 53.08  ? 109 GLY C N   1 
ATOM 4300 C CA  . GLY C 1 109 ? 273.766 279.493 102.386 1.00 53.08  ? 109 GLY C CA  1 
ATOM 4301 C C   . GLY C 1 109 ? 272.481 279.518 103.185 1.00 53.08  ? 109 GLY C C   1 
ATOM 4302 O O   . GLY C 1 109 ? 271.897 280.585 103.399 1.00 53.08  ? 109 GLY C O   1 
ATOM 4303 N N   . ARG C 1 110 ? 272.031 278.351 103.640 1.00 49.83  ? 110 ARG C N   1 
ATOM 4304 C CA  . ARG C 1 110 ? 270.767 278.251 104.349 1.00 49.83  ? 110 ARG C CA  1 
ATOM 4305 C C   . ARG C 1 110 ? 270.929 277.899 105.818 1.00 49.83  ? 110 ARG C C   1 
ATOM 4306 O O   . ARG C 1 110 ? 269.948 277.966 106.564 1.00 49.83  ? 110 ARG C O   1 
ATOM 4307 C CB  . ARG C 1 110 ? 269.861 277.214 103.676 1.00 49.83  ? 110 ARG C CB  1 
ATOM 4308 C CG  . ARG C 1 110 ? 269.308 277.672 102.344 1.00 49.83  ? 110 ARG C CG  1 
ATOM 4309 C CD  . ARG C 1 110 ? 270.132 277.121 101.197 1.00 49.83  ? 110 ARG C CD  1 
ATOM 4310 N NE  . ARG C 1 110 ? 269.630 277.532 99.892  1.00 49.83  ? 110 ARG C NE  1 
ATOM 4311 C CZ  . ARG C 1 110 ? 268.685 276.887 99.222  1.00 49.83  ? 110 ARG C CZ  1 
ATOM 4312 N NH1 . ARG C 1 110 ? 268.130 275.804 99.744  1.00 49.83  ? 110 ARG C NH1 1 
ATOM 4313 N NH2 . ARG C 1 110 ? 268.294 277.325 98.035  1.00 49.83  ? 110 ARG C NH2 1 
ATOM 4314 N N   . MET C 1 111 ? 272.123 277.509 106.246 1.00 31.45  ? 111 MET C N   1 
ATOM 4315 C CA  . MET C 1 111 ? 272.399 277.248 107.647 1.00 31.45  ? 111 MET C CA  1 
ATOM 4316 C C   . MET C 1 111 ? 273.645 278.016 108.048 1.00 31.45  ? 111 MET C C   1 
ATOM 4317 O O   . MET C 1 111 ? 274.662 277.965 107.354 1.00 31.45  ? 111 MET C O   1 
ATOM 4318 C CB  . MET C 1 111 ? 272.600 275.755 107.925 1.00 31.45  ? 111 MET C CB  1 
ATOM 4319 C CG  . MET C 1 111 ? 271.536 274.835 107.365 1.00 31.45  ? 111 MET C CG  1 
ATOM 4320 S SD  . MET C 1 111 ? 271.223 273.414 108.414 1.00 31.45  ? 111 MET C SD  1 
ATOM 4321 C CE  . MET C 1 111 ? 270.510 274.208 109.839 1.00 31.45  ? 111 MET C CE  1 
ATOM 4322 N N   . ASP C 1 112 ? 273.562 278.734 109.162 1.00 28.99  ? 112 ASP C N   1 
ATOM 4323 C CA  . ASP C 1 112 ? 274.696 279.468 109.717 1.00 28.99  ? 112 ASP C CA  1 
ATOM 4324 C C   . ASP C 1 112 ? 275.203 278.678 110.910 1.00 28.99  ? 112 ASP C C   1 
ATOM 4325 O O   . ASP C 1 112 ? 274.697 278.825 112.023 1.00 28.99  ? 112 ASP C O   1 
ATOM 4326 C CB  . ASP C 1 112 ? 274.308 280.883 110.124 1.00 28.99  ? 112 ASP C CB  1 
ATOM 4327 C CG  . ASP C 1 112 ? 275.432 281.611 110.835 1.00 28.99  ? 112 ASP C CG  1 
ATOM 4328 O OD1 . ASP C 1 112 ? 276.335 282.139 110.153 1.00 28.99  ? 112 ASP C OD1 1 
ATOM 4329 O OD2 . ASP C 1 112 ? 275.414 281.650 112.081 1.00 28.99  ? 112 ASP C OD2 1 
ATOM 4330 N N   . ILE C 1 113 ? 276.202 277.842 110.675 1.00 20.29  ? 113 ILE C N   1 
ATOM 4331 C CA  . ILE C 1 113 ? 276.729 276.934 111.679 1.00 20.29  ? 113 ILE C CA  1 
ATOM 4332 C C   . ILE C 1 113 ? 278.186 277.297 111.909 1.00 20.29  ? 113 ILE C C   1 
ATOM 4333 O O   . ILE C 1 113 ? 278.949 277.434 110.947 1.00 20.29  ? 113 ILE C O   1 
ATOM 4334 C CB  . ILE C 1 113 ? 276.563 275.470 111.228 1.00 20.29  ? 113 ILE C CB  1 
ATOM 4335 C CG1 . ILE C 1 113 ? 275.139 274.985 111.494 1.00 20.29  ? 113 ILE C CG1 1 
ATOM 4336 C CG2 . ILE C 1 113 ? 277.540 274.564 111.908 1.00 20.29  ? 113 ILE C CG2 1 
ATOM 4337 C CD1 . ILE C 1 113 ? 274.792 273.719 110.780 1.00 20.29  ? 113 ILE C CD1 1 
ATOM 4338 N N   . ASP C 1 114 ? 278.557 277.518 113.175 1.00 21.17  ? 114 ASP C N   1 
ATOM 4339 C CA  . ASP C 1 114 ? 279.999 277.586 113.389 1.00 21.17  ? 114 ASP C CA  1 
ATOM 4340 C C   . ASP C 1 114 ? 280.552 276.207 113.705 1.00 21.17  ? 114 ASP C C   1 
ATOM 4341 O O   . ASP C 1 114 ? 279.905 275.424 114.402 1.00 21.17  ? 114 ASP C O   1 
ATOM 4342 C CB  . ASP C 1 114 ? 280.362 278.515 114.539 1.00 21.17  ? 114 ASP C CB  1 
ATOM 4343 C CG  . ASP C 1 114 ? 280.379 279.957 114.141 1.00 21.17  ? 114 ASP C CG  1 
ATOM 4344 O OD1 . ASP C 1 114 ? 280.579 280.243 112.948 1.00 21.17  ? 114 ASP C OD1 1 
ATOM 4345 O OD2 . ASP C 1 114 ? 280.223 280.816 115.029 1.00 21.17  ? 114 ASP C OD2 1 
ATOM 4346 N N   . PRO C 1 115 ? 281.753 275.897 113.222 1.00 18.45  ? 115 PRO C N   1 
ATOM 4347 C CA  . PRO C 1 115 ? 282.449 274.724 113.749 1.00 18.45  ? 115 PRO C CA  1 
ATOM 4348 C C   . PRO C 1 115 ? 282.848 274.896 115.198 1.00 18.45  ? 115 PRO C C   1 
ATOM 4349 O O   . PRO C 1 115 ? 283.000 273.900 115.915 1.00 18.45  ? 115 PRO C O   1 
ATOM 4350 C CB  . PRO C 1 115 ? 283.674 274.601 112.839 1.00 18.45  ? 115 PRO C CB  1 
ATOM 4351 C CG  . PRO C 1 115 ? 283.474 275.557 111.737 1.00 18.45  ? 115 PRO C CG  1 
ATOM 4352 C CD  . PRO C 1 115 ? 282.521 276.583 112.178 1.00 18.45  ? 115 PRO C CD  1 
ATOM 4353 N N   . TYR C 1 116 ? 283.024 276.136 115.646 1.00 13.35  ? 116 TYR C N   1 
ATOM 4354 C CA  . TYR C 1 116 ? 283.437 276.476 116.996 1.00 13.35  ? 116 TYR C CA  1 
ATOM 4355 C C   . TYR C 1 116 ? 282.314 277.363 117.503 1.00 13.35  ? 116 TYR C C   1 
ATOM 4356 O O   . TYR C 1 116 ? 282.351 278.566 117.299 1.00 13.35  ? 116 TYR C O   1 
ATOM 4357 C CB  . TYR C 1 116 ? 284.719 277.233 116.994 1.00 13.35  ? 116 TYR C CB  1 
ATOM 4358 C CG  . TYR C 1 116 ? 285.692 276.908 115.892 1.00 13.35  ? 116 TYR C CG  1 
ATOM 4359 C CD1 . TYR C 1 116 ? 286.594 275.878 115.999 1.00 13.35  ? 116 TYR C CD1 1 
ATOM 4360 C CD2 . TYR C 1 116 ? 285.706 277.667 114.737 1.00 13.35  ? 116 TYR C CD2 1 
ATOM 4361 C CE1 . TYR C 1 116 ? 287.478 275.616 114.974 1.00 13.35  ? 116 TYR C CE1 1 
ATOM 4362 C CE2 . TYR C 1 116 ? 286.563 277.405 113.723 1.00 13.35  ? 116 TYR C CE2 1 
ATOM 4363 C CZ  . TYR C 1 116 ? 287.454 276.391 113.839 1.00 13.35  ? 116 TYR C CZ  1 
ATOM 4364 O OH  . TYR C 1 116 ? 288.294 276.159 112.787 1.00 13.35  ? 116 TYR C OH  1 
ATOM 4365 N N   . LYS C 1 117 ? 281.262 276.780 118.013 1.00 19.08  ? 117 LYS C N   1 
ATOM 4366 C CA  . LYS C 1 117 ? 280.357 277.533 118.872 1.00 19.08  ? 117 LYS C CA  1 
ATOM 4367 C C   . LYS C 1 117 ? 279.876 276.729 120.061 1.00 19.08  ? 117 LYS C C   1 
ATOM 4368 O O   . LYS C 1 117 ? 279.601 277.305 121.116 1.00 19.08  ? 117 LYS C O   1 
ATOM 4369 C CB  . LYS C 1 117 ? 279.150 278.033 118.082 1.00 19.08  ? 117 LYS C CB  1 
ATOM 4370 C CG  . LYS C 1 117 ? 278.520 279.285 118.636 1.00 19.08  ? 117 LYS C CG  1 
ATOM 4371 C CD  . LYS C 1 117 ? 277.740 280.022 117.584 1.00 19.08  ? 117 LYS C CD  1 
ATOM 4372 C CE  . LYS C 1 117 ? 276.695 280.897 118.222 1.00 19.08  ? 117 LYS C CE  1 
ATOM 4373 N NZ  . LYS C 1 117 ? 275.804 280.093 119.084 1.00 19.08  ? 117 LYS C NZ  1 
ATOM 4374 N N   . GLU C 1 118 ? 279.789 275.414 119.925 1.00 19.82  ? 118 GLU C N   1 
ATOM 4375 C CA  . GLU C 1 118 ? 279.543 274.468 120.993 1.00 19.82  ? 118 GLU C CA  1 
ATOM 4376 C C   . GLU C 1 118 ? 280.724 274.320 121.927 1.00 19.82  ? 118 GLU C C   1 
ATOM 4377 O O   . GLU C 1 118 ? 280.581 273.708 122.990 1.00 19.82  ? 118 GLU C O   1 
ATOM 4378 C CB  . GLU C 1 118 ? 279.190 273.138 120.352 1.00 19.82  ? 118 GLU C CB  1 
ATOM 4379 C CG  . GLU C 1 118 ? 280.098 272.865 119.180 1.00 19.82  ? 118 GLU C CG  1 
ATOM 4380 C CD  . GLU C 1 118 ? 279.833 271.554 118.508 1.00 19.82  ? 118 GLU C CD  1 
ATOM 4381 O OE1 . GLU C 1 118 ? 279.057 270.748 119.054 1.00 19.82  ? 118 GLU C OE1 1 
ATOM 4382 O OE2 . GLU C 1 118 ? 280.358 271.343 117.406 1.00 19.82  ? 118 GLU C OE2 1 
ATOM 4383 N N   . PHE C 1 119 ? 281.880 274.853 121.552 1.00 14.78  ? 119 PHE C N   1 
ATOM 4384 C CA  . PHE C 1 119 ? 283.090 274.742 122.342 1.00 14.78  ? 119 PHE C CA  1 
ATOM 4385 C C   . PHE C 1 119 ? 283.431 276.017 123.083 1.00 14.78  ? 119 PHE C C   1 
ATOM 4386 O O   . PHE C 1 119 ? 284.044 275.953 124.145 1.00 14.78  ? 119 PHE C O   1 
ATOM 4387 C CB  . PHE C 1 119 ? 284.251 274.332 121.436 1.00 14.78  ? 119 PHE C CB  1 
ATOM 4388 C CG  . PHE C 1 119 ? 283.967 273.094 120.647 1.00 14.78  ? 119 PHE C CG  1 
ATOM 4389 C CD1 . PHE C 1 119 ? 283.757 271.889 121.287 1.00 14.78  ? 119 PHE C CD1 1 
ATOM 4390 C CD2 . PHE C 1 119 ? 283.877 273.137 119.278 1.00 14.78  ? 119 PHE C CD2 1 
ATOM 4391 C CE1 . PHE C 1 119 ? 283.475 270.755 120.573 1.00 14.78  ? 119 PHE C CE1 1 
ATOM 4392 C CE2 . PHE C 1 119 ? 283.593 271.997 118.562 1.00 14.78  ? 119 PHE C CE2 1 
ATOM 4393 C CZ  . PHE C 1 119 ? 283.398 270.808 119.214 1.00 14.78  ? 119 PHE C CZ  1 
ATOM 4394 N N   . GLY C 1 120 ? 283.028 277.170 122.575 1.00 11.19  ? 120 GLY C N   1 
ATOM 4395 C CA  . GLY C 1 120 ? 283.273 278.440 123.225 1.00 11.19  ? 120 GLY C CA  1 
ATOM 4396 C C   . GLY C 1 120 ? 283.976 279.448 122.354 1.00 11.19  ? 120 GLY C C   1 
ATOM 4397 O O   . GLY C 1 120 ? 283.984 280.637 122.686 1.00 11.19  ? 120 GLY C O   1 
ATOM 4398 N N   . ALA C 1 121 ? 284.565 279.020 121.257 1.00 10.37  ? 121 ALA C N   1 
ATOM 4399 C CA  . ALA C 1 121 ? 285.233 279.935 120.359 1.00 10.37  ? 121 ALA C CA  1 
ATOM 4400 C C   . ALA C 1 121 ? 284.224 280.433 119.347 1.00 10.37  ? 121 ALA C C   1 
ATOM 4401 O O   . ALA C 1 121 ? 283.027 280.190 119.477 1.00 10.37  ? 121 ALA C O   1 
ATOM 4402 C CB  . ALA C 1 121 ? 286.407 279.254 119.677 1.00 10.37  ? 121 ALA C CB  1 
ATOM 4403 N N   . THR C 1 122 ? 284.700 281.177 118.358 1.00 11.42  ? 122 THR C N   1 
ATOM 4404 C CA  . THR C 1 122 ? 283.984 281.494 117.139 1.00 11.42  ? 122 THR C CA  1 
ATOM 4405 C C   . THR C 1 122 ? 284.995 281.407 116.015 1.00 11.42  ? 122 THR C C   1 
ATOM 4406 O O   . THR C 1 122 ? 286.173 281.158 116.246 1.00 11.42  ? 122 THR C O   1 
ATOM 4407 C CB  . THR C 1 122 ? 283.341 282.888 117.157 1.00 11.42  ? 122 THR C CB  1 
ATOM 4408 O OG1 . THR C 1 122 ? 284.314 283.874 117.516 1.00 11.42  ? 122 THR C OG1 1 
ATOM 4409 C CG2 . THR C 1 122 ? 282.150 282.972 118.103 1.00 11.42  ? 122 THR C CG2 1 
ATOM 4410 N N   . VAL C 1 123 ? 284.543 281.628 114.788 1.00 14.12  ? 123 VAL C N   1 
ATOM 4411 C CA  . VAL C 1 123 ? 285.465 281.563 113.665 1.00 14.12  ? 123 VAL C CA  1 
ATOM 4412 C C   . VAL C 1 123 ? 286.326 282.811 113.611 1.00 14.12  ? 123 VAL C C   1 
ATOM 4413 O O   . VAL C 1 123 ? 287.465 282.768 113.138 1.00 14.12  ? 123 VAL C O   1 
ATOM 4414 C CB  . VAL C 1 123 ? 284.674 281.345 112.368 1.00 14.12  ? 123 VAL C CB  1 
ATOM 4415 C CG1 . VAL C 1 123 ? 285.579 281.149 111.176 1.00 14.12  ? 123 VAL C CG1 1 
ATOM 4416 C CG2 . VAL C 1 123 ? 283.805 280.147 112.525 1.00 14.12  ? 123 VAL C CG2 1 
ATOM 4417 N N   . GLU C 1 124 ? 285.825 283.933 114.118 1.00 28.56  ? 124 GLU C N   1 
ATOM 4418 C CA  . GLU C 1 124 ? 286.626 285.148 114.110 1.00 28.56  ? 124 GLU C CA  1 
ATOM 4419 C C   . GLU C 1 124 ? 287.715 285.110 115.169 1.00 28.56  ? 124 GLU C C   1 
ATOM 4420 O O   . GLU C 1 124 ? 288.760 285.741 115.005 1.00 28.56  ? 124 GLU C O   1 
ATOM 4421 C CB  . GLU C 1 124 ? 285.739 286.360 114.324 1.00 28.56  ? 124 GLU C CB  1 
ATOM 4422 C CG  . GLU C 1 124 ? 286.368 287.655 113.904 1.00 28.56  ? 124 GLU C CG  1 
ATOM 4423 C CD  . GLU C 1 124 ? 285.564 288.835 114.357 1.00 28.56  ? 124 GLU C CD  1 
ATOM 4424 O OE1 . GLU C 1 124 ? 284.594 288.616 115.109 1.00 28.56  ? 124 GLU C OE1 1 
ATOM 4425 O OE2 . GLU C 1 124 ? 285.899 289.973 113.969 1.00 28.56  ? 124 GLU C OE2 1 
ATOM 4426 N N   . LEU C 1 125 ? 287.497 284.372 116.253 1.00 10.58  ? 125 LEU C N   1 
ATOM 4427 C CA  . LEU C 1 125 ? 288.533 284.218 117.262 1.00 10.58  ? 125 LEU C CA  1 
ATOM 4428 C C   . LEU C 1 125 ? 289.681 283.358 116.756 1.00 10.58  ? 125 LEU C C   1 
ATOM 4429 O O   . LEU C 1 125 ? 290.803 283.475 117.251 1.00 10.58  ? 125 LEU C O   1 
ATOM 4430 C CB  . LEU C 1 125 ? 287.923 283.626 118.525 1.00 10.58  ? 125 LEU C CB  1 
ATOM 4431 C CG  . LEU C 1 125 ? 288.764 283.422 119.773 1.00 10.58  ? 125 LEU C CG  1 
ATOM 4432 C CD1 . LEU C 1 125 ? 289.519 284.672 120.076 1.00 10.58  ? 125 LEU C CD1 1 
ATOM 4433 C CD2 . LEU C 1 125 ? 287.890 283.060 120.934 1.00 10.58  ? 125 LEU C CD2 1 
ATOM 4434 N N   . LEU C 1 126 ? 289.444 282.505 115.770 1.00 11.18  ? 126 LEU C N   1 
ATOM 4435 C CA  . LEU C 1 126 ? 290.541 281.726 115.226 1.00 11.18  ? 126 LEU C CA  1 
ATOM 4436 C C   . LEU C 1 126 ? 291.172 282.360 114.003 1.00 11.18  ? 126 LEU C C   1 
ATOM 4437 O O   . LEU C 1 126 ? 292.239 281.916 113.584 1.00 11.18  ? 126 LEU C O   1 
ATOM 4438 C CB  . LEU C 1 126 ? 290.102 280.300 114.895 1.00 11.18  ? 126 LEU C CB  1 
ATOM 4439 C CG  . LEU C 1 126 ? 290.156 279.344 116.086 1.00 11.18  ? 126 LEU C CG  1 
ATOM 4440 C CD1 . LEU C 1 126 ? 288.928 279.402 116.947 1.00 11.18  ? 126 LEU C CD1 1 
ATOM 4441 C CD2 . LEU C 1 126 ? 290.445 277.948 115.655 1.00 11.18  ? 126 LEU C CD2 1 
ATOM 4442 N N   . SER C 1 127 ? 290.552 283.369 113.415 1.00 28.56  ? 127 SER C N   1 
ATOM 4443 C CA  . SER C 1 127 ? 291.238 284.221 112.461 1.00 28.56  ? 127 SER C CA  1 
ATOM 4444 C C   . SER C 1 127 ? 291.810 285.458 113.133 1.00 28.56  ? 127 SER C C   1 
ATOM 4445 O O   . SER C 1 127 ? 292.289 286.366 112.450 1.00 28.56  ? 127 SER C O   1 
ATOM 4446 C CB  . SER C 1 127 ? 290.301 284.607 111.324 1.00 28.56  ? 127 SER C CB  1 
ATOM 4447 O OG  . SER C 1 127 ? 289.019 284.920 111.821 1.00 28.56  ? 127 SER C OG  1 
ATOM 4448 N N   . PHE C 1 128 ? 291.751 285.506 114.463 1.00 10.50  ? 128 PHE C N   1 
ATOM 4449 C CA  . PHE C 1 128 ? 292.452 286.522 115.231 1.00 10.50  ? 128 PHE C CA  1 
ATOM 4450 C C   . PHE C 1 128 ? 293.950 286.287 115.174 1.00 10.50  ? 128 PHE C C   1 
ATOM 4451 O O   . PHE C 1 128 ? 294.726 287.234 115.027 1.00 10.50  ? 128 PHE C O   1 
ATOM 4452 C CB  . PHE C 1 128 ? 291.941 286.485 116.669 1.00 10.50  ? 128 PHE C CB  1 
ATOM 4453 C CG  . PHE C 1 128 ? 292.293 287.677 117.497 1.00 10.50  ? 128 PHE C CG  1 
ATOM 4454 C CD1 . PHE C 1 128 ? 292.625 288.878 116.921 1.00 10.50  ? 128 PHE C CD1 1 
ATOM 4455 C CD2 . PHE C 1 128 ? 292.230 287.598 118.871 1.00 10.50  ? 128 PHE C CD2 1 
ATOM 4456 C CE1 . PHE C 1 128 ? 292.927 289.954 117.688 1.00 10.50  ? 128 PHE C CE1 1 
ATOM 4457 C CE2 . PHE C 1 128 ? 292.529 288.676 119.642 1.00 10.50  ? 128 PHE C CE2 1 
ATOM 4458 C CZ  . PHE C 1 128 ? 292.877 289.850 119.049 1.00 10.50  ? 128 PHE C CZ  1 
ATOM 4459 N N   . LEU C 1 129 ? 294.369 285.029 115.275 1.00 9.98   ? 129 LEU C N   1 
ATOM 4460 C CA  . LEU C 1 129 ? 295.754 284.651 115.066 1.00 9.98   ? 129 LEU C CA  1 
ATOM 4461 C C   . LEU C 1 129 ? 296.103 284.827 113.593 1.00 9.98   ? 129 LEU C C   1 
ATOM 4462 O O   . LEU C 1 129 ? 295.212 284.845 112.744 1.00 9.98   ? 129 LEU C O   1 
ATOM 4463 C CB  . LEU C 1 129 ? 295.974 283.206 115.495 1.00 9.98   ? 129 LEU C CB  1 
ATOM 4464 C CG  . LEU C 1 129 ? 295.455 282.785 116.863 1.00 9.98   ? 129 LEU C CG  1 
ATOM 4465 C CD1 . LEU C 1 129 ? 295.930 281.421 117.177 1.00 9.98   ? 129 LEU C CD1 1 
ATOM 4466 C CD2 . LEU C 1 129 ? 295.930 283.705 117.923 1.00 9.98   ? 129 LEU C CD2 1 
ATOM 4467 N N   . PRO C 1 130 ? 297.386 284.994 113.261 1.00 11.99  ? 130 PRO C N   1 
ATOM 4468 C CA  . PRO C 1 130 ? 297.767 285.117 111.851 1.00 11.99  ? 130 PRO C CA  1 
ATOM 4469 C C   . PRO C 1 130 ? 297.473 283.848 111.073 1.00 11.99  ? 130 PRO C C   1 
ATOM 4470 O O   . PRO C 1 130 ? 297.221 282.781 111.633 1.00 11.99  ? 130 PRO C O   1 
ATOM 4471 C CB  . PRO C 1 130 ? 299.266 285.393 111.910 1.00 11.99  ? 130 PRO C CB  1 
ATOM 4472 C CG  . PRO C 1 130 ? 299.481 285.962 113.212 1.00 11.99  ? 130 PRO C CG  1 
ATOM 4473 C CD  . PRO C 1 130 ? 298.501 285.372 114.143 1.00 11.99  ? 130 PRO C CD  1 
ATOM 4474 N N   . SER C 1 131 ? 297.462 283.993 109.751 1.00 28.56  ? 131 SER C N   1 
ATOM 4475 C CA  . SER C 1 131 ? 297.140 282.866 108.887 1.00 28.56  ? 131 SER C CA  1 
ATOM 4476 C C   . SER C 1 131 ? 298.200 281.787 108.984 1.00 28.56  ? 131 SER C C   1 
ATOM 4477 O O   . SER C 1 131 ? 297.889 280.622 109.242 1.00 28.56  ? 131 SER C O   1 
ATOM 4478 C CB  . SER C 1 131 ? 296.995 283.337 107.448 1.00 28.56  ? 131 SER C CB  1 
ATOM 4479 O OG  . SER C 1 131 ? 297.150 282.248 106.564 1.00 28.56  ? 131 SER C OG  1 
ATOM 4480 N N   . ASP C 1 132 ? 299.460 282.166 108.843 1.00 12.88  ? 132 ASP C N   1 
ATOM 4481 C CA  . ASP C 1 132 ? 300.567 281.227 108.882 1.00 12.88  ? 132 ASP C CA  1 
ATOM 4482 C C   . ASP C 1 132 ? 301.032 280.909 110.279 1.00 12.88  ? 132 ASP C C   1 
ATOM 4483 O O   . ASP C 1 132 ? 302.153 280.445 110.427 1.00 12.88  ? 132 ASP C O   1 
ATOM 4484 C CB  . ASP C 1 132 ? 301.742 281.771 108.080 1.00 12.88  ? 132 ASP C CB  1 
ATOM 4485 C CG  . ASP C 1 132 ? 302.225 283.097 108.600 1.00 12.88  ? 132 ASP C CG  1 
ATOM 4486 O OD1 . ASP C 1 132 ? 301.397 284.021 108.715 1.00 12.88  ? 132 ASP C OD1 1 
ATOM 4487 O OD2 . ASP C 1 132 ? 303.428 283.222 108.895 1.00 12.88  ? 132 ASP C OD2 1 
ATOM 4488 N N   . PHE C 1 133 ? 300.239 281.160 111.313 1.00 12.02  ? 133 PHE C N   1 
ATOM 4489 C CA  . PHE C 1 133 ? 300.614 280.666 112.626 1.00 12.02  ? 133 PHE C CA  1 
ATOM 4490 C C   . PHE C 1 133 ? 300.403 279.169 112.713 1.00 12.02  ? 133 PHE C C   1 
ATOM 4491 O O   . PHE C 1 133 ? 301.183 278.466 113.359 1.00 12.02  ? 133 PHE C O   1 
ATOM 4492 C CB  . PHE C 1 133 ? 299.816 281.364 113.717 1.00 12.02  ? 133 PHE C CB  1 
ATOM 4493 C CG  . PHE C 1 133 ? 299.867 280.665 115.025 1.00 12.02  ? 133 PHE C CG  1 
ATOM 4494 C CD1 . PHE C 1 133 ? 301.030 280.632 115.750 1.00 12.02  ? 133 PHE C CD1 1 
ATOM 4495 C CD2 . PHE C 1 133 ? 298.768 280.017 115.521 1.00 12.02  ? 133 PHE C CD2 1 
ATOM 4496 C CE1 . PHE C 1 133 ? 301.082 279.976 116.950 1.00 12.02  ? 133 PHE C CE1 1 
ATOM 4497 C CE2 . PHE C 1 133 ? 298.820 279.356 116.713 1.00 12.02  ? 133 PHE C CE2 1 
ATOM 4498 C CZ  . PHE C 1 133 ? 299.971 279.338 117.426 1.00 12.02  ? 133 PHE C CZ  1 
ATOM 4499 N N   . PHE C 1 134 ? 299.373 278.669 112.072 1.00 11.81  ? 134 PHE C N   1 
ATOM 4500 C CA  . PHE C 1 134 ? 298.933 277.307 112.315 1.00 11.81  ? 134 PHE C CA  1 
ATOM 4501 C C   . PHE C 1 134 ? 299.865 276.329 111.620 1.00 11.81  ? 134 PHE C C   1 
ATOM 4502 O O   . PHE C 1 134 ? 300.211 276.540 110.454 1.00 11.81  ? 134 PHE C O   1 
ATOM 4503 C CB  . PHE C 1 134 ? 297.510 277.126 111.837 1.00 11.81  ? 134 PHE C CB  1 
ATOM 4504 C CG  . PHE C 1 134 ? 296.530 277.965 112.576 1.00 11.81  ? 134 PHE C CG  1 
ATOM 4505 C CD1 . PHE C 1 134 ? 296.072 277.577 113.812 1.00 11.81  ? 134 PHE C CD1 1 
ATOM 4506 C CD2 . PHE C 1 134 ? 296.076 279.145 112.048 1.00 11.81  ? 134 PHE C CD2 1 
ATOM 4507 C CE1 . PHE C 1 134 ? 295.175 278.344 114.494 1.00 11.81  ? 134 PHE C CE1 1 
ATOM 4508 C CE2 . PHE C 1 134 ? 295.191 279.913 112.735 1.00 11.81  ? 134 PHE C CE2 1 
ATOM 4509 C CZ  . PHE C 1 134 ? 294.743 279.507 113.954 1.00 11.81  ? 134 PHE C CZ  1 
ATOM 4510 N N   . PRO C 1 135 ? 300.324 275.291 112.317 1.00 13.28  ? 135 PRO C N   1 
ATOM 4511 C CA  . PRO C 1 135 ? 301.207 274.306 111.696 1.00 13.28  ? 135 PRO C CA  1 
ATOM 4512 C C   . PRO C 1 135 ? 300.479 273.570 110.596 1.00 13.28  ? 135 PRO C C   1 
ATOM 4513 O O   . PRO C 1 135 ? 299.261 273.422 110.636 1.00 13.28  ? 135 PRO C O   1 
ATOM 4514 C CB  . PRO C 1 135 ? 301.550 273.372 112.854 1.00 13.28  ? 135 PRO C CB  1 
ATOM 4515 C CG  . PRO C 1 135 ? 300.431 273.542 113.802 1.00 13.28  ? 135 PRO C CG  1 
ATOM 4516 C CD  . PRO C 1 135 ? 300.056 274.966 113.724 1.00 13.28  ? 135 PRO C CD  1 
ATOM 4517 N N   . SER C 1 136 ? 301.238 273.115 109.607 1.00 13.29  ? 136 SER C N   1 
ATOM 4518 C CA  . SER C 1 136 ? 300.637 272.568 108.404 1.00 13.29  ? 136 SER C CA  1 
ATOM 4519 C C   . SER C 1 136 ? 299.938 271.248 108.704 1.00 13.29  ? 136 SER C C   1 
ATOM 4520 O O   . SER C 1 136 ? 300.097 270.657 109.770 1.00 13.29  ? 136 SER C O   1 
ATOM 4521 C CB  . SER C 1 136 ? 301.682 272.382 107.317 1.00 13.29  ? 136 SER C CB  1 
ATOM 4522 O OG  . SER C 1 136 ? 301.153 271.586 106.280 1.00 13.29  ? 136 SER C OG  1 
ATOM 4523 N N   . VAL C 1 137 ? 299.123 270.804 107.748 1.00 17.80  ? 137 VAL C N   1 
ATOM 4524 C CA  . VAL C 1 137 ? 298.165 269.741 108.024 1.00 17.80  ? 137 VAL C CA  1 
ATOM 4525 C C   . VAL C 1 137 ? 298.873 268.400 108.161 1.00 17.80  ? 137 VAL C C   1 
ATOM 4526 O O   . VAL C 1 137 ? 298.410 267.520 108.894 1.00 17.80  ? 137 VAL C O   1 
ATOM 4527 C CB  . VAL C 1 137 ? 297.075 269.753 106.935 1.00 17.80  ? 137 VAL C CB  1 
ATOM 4528 C CG1 . VAL C 1 137 ? 297.675 269.575 105.566 1.00 17.80  ? 137 VAL C CG1 1 
ATOM 4529 C CG2 . VAL C 1 137 ? 295.995 268.743 107.211 1.00 17.80  ? 137 VAL C CG2 1 
ATOM 4530 N N   . ARG C 1 138 ? 300.037 268.256 107.527 1.00 31.22  ? 138 ARG C N   1 
ATOM 4531 C CA  . ARG C 1 138 ? 300.878 267.083 107.729 1.00 31.22  ? 138 ARG C CA  1 
ATOM 4532 C C   . ARG C 1 138 ? 301.308 266.963 109.181 1.00 31.22  ? 138 ARG C C   1 
ATOM 4533 O O   . ARG C 1 138 ? 301.164 265.901 109.798 1.00 31.22  ? 138 ARG C O   1 
ATOM 4534 C CB  . ARG C 1 138 ? 302.094 267.179 106.819 1.00 31.22  ? 138 ARG C CB  1 
ATOM 4535 C CG  . ARG C 1 138 ? 303.221 266.263 107.194 1.00 31.22  ? 138 ARG C CG  1 
ATOM 4536 C CD  . ARG C 1 138 ? 302.905 264.851 106.806 1.00 31.22  ? 138 ARG C CD  1 
ATOM 4537 N NE  . ARG C 1 138 ? 302.317 264.799 105.475 1.00 31.22  ? 138 ARG C NE  1 
ATOM 4538 C CZ  . ARG C 1 138 ? 302.949 264.342 104.403 1.00 31.22  ? 138 ARG C CZ  1 
ATOM 4539 N NH1 . ARG C 1 138 ? 302.342 264.331 103.230 1.00 31.22  ? 138 ARG C NH1 1 
ATOM 4540 N NH2 . ARG C 1 138 ? 304.196 263.911 104.501 1.00 31.22  ? 138 ARG C NH2 1 
ATOM 4541 N N   . ASP C 1 139 ? 301.778 268.068 109.755 1.00 20.91  ? 139 ASP C N   1 
ATOM 4542 C CA  . ASP C 1 139 ? 302.272 268.073 111.124 1.00 20.91  ? 139 ASP C CA  1 
ATOM 4543 C C   . ASP C 1 139 ? 301.148 267.854 112.120 1.00 20.91  ? 139 ASP C C   1 
ATOM 4544 O O   . ASP C 1 139 ? 301.331 267.171 113.131 1.00 20.91  ? 139 ASP C O   1 
ATOM 4545 C CB  . ASP C 1 139 ? 302.969 269.393 111.396 1.00 20.91  ? 139 ASP C CB  1 
ATOM 4546 C CG  . ASP C 1 139 ? 304.203 269.568 110.566 1.00 20.91  ? 139 ASP C CG  1 
ATOM 4547 O OD1 . ASP C 1 139 ? 305.134 268.753 110.720 1.00 20.91  ? 139 ASP C OD1 1 
ATOM 4548 O OD2 . ASP C 1 139 ? 304.247 270.514 109.754 1.00 20.91  ? 139 ASP C OD2 1 
ATOM 4549 N N   . LEU C 1 140 ? 299.964 268.380 111.825 1.00 12.85  ? 140 LEU C N   1 
ATOM 4550 C CA  . LEU C 1 140 ? 298.834 268.225 112.726 1.00 12.85  ? 140 LEU C CA  1 
ATOM 4551 C C   . LEU C 1 140 ? 298.222 266.837 112.645 1.00 12.85  ? 140 LEU C C   1 
ATOM 4552 O O   . LEU C 1 140 ? 297.763 266.311 113.660 1.00 12.85  ? 140 LEU C O   1 
ATOM 4553 C CB  . LEU C 1 140 ? 297.792 269.288 112.423 1.00 12.85  ? 140 LEU C CB  1 
ATOM 4554 C CG  . LEU C 1 140 ? 298.134 270.631 113.044 1.00 12.85  ? 140 LEU C CG  1 
ATOM 4555 C CD1 . LEU C 1 140 ? 297.141 271.669 112.610 1.00 12.85  ? 140 LEU C CD1 1 
ATOM 4556 C CD2 . LEU C 1 140 ? 298.156 270.509 114.550 1.00 12.85  ? 140 LEU C CD2 1 
ATOM 4557 N N   . LEU C 1 141 ? 298.241 266.204 111.475 1.00 16.32  ? 141 LEU C N   1 
ATOM 4558 C CA  . LEU C 1 141 ? 297.769 264.829 111.413 1.00 16.32  ? 141 LEU C CA  1 
ATOM 4559 C C   . LEU C 1 141 ? 298.759 263.872 112.057 1.00 16.32  ? 141 LEU C C   1 
ATOM 4560 O O   . LEU C 1 141 ? 298.341 262.891 112.680 1.00 16.32  ? 141 LEU C O   1 
ATOM 4561 C CB  . LEU C 1 141 ? 297.482 264.437 109.970 1.00 16.32  ? 141 LEU C CB  1 
ATOM 4562 C CG  . LEU C 1 141 ? 296.231 265.119 109.429 1.00 16.32  ? 141 LEU C CG  1 
ATOM 4563 C CD1 . LEU C 1 141 ? 296.084 264.874 107.960 1.00 16.32  ? 141 LEU C CD1 1 
ATOM 4564 C CD2 . LEU C 1 141 ? 295.021 264.639 110.161 1.00 16.32  ? 141 LEU C CD2 1 
ATOM 4565 N N   . ASP C 1 142 ? 300.063 264.155 111.954 1.00 19.98  ? 142 ASP C N   1 
ATOM 4566 C CA  . ASP C 1 142 ? 301.051 263.376 112.699 1.00 19.98  ? 142 ASP C CA  1 
ATOM 4567 C C   . ASP C 1 142 ? 300.888 263.559 114.199 1.00 19.98  ? 142 ASP C C   1 
ATOM 4568 O O   . ASP C 1 142 ? 300.994 262.593 114.961 1.00 19.98  ? 142 ASP C O   1 
ATOM 4569 C CB  . ASP C 1 142 ? 302.460 263.770 112.279 1.00 19.98  ? 142 ASP C CB  1 
ATOM 4570 C CG  . ASP C 1 142 ? 302.745 263.453 110.835 1.00 19.98  ? 142 ASP C CG  1 
ATOM 4571 O OD1 . ASP C 1 142 ? 303.905 263.620 110.411 1.00 19.98  ? 142 ASP C OD1 1 
ATOM 4572 O OD2 . ASP C 1 142 ? 301.807 263.054 110.116 1.00 19.98  ? 142 ASP C OD2 1 
ATOM 4573 N N   . THR C 1 143 ? 300.600 264.787 114.635 1.00 14.69  ? 143 THR C N   1 
ATOM 4574 C CA  . THR C 1 143 ? 300.347 265.059 116.046 1.00 14.69  ? 143 THR C CA  1 
ATOM 4575 C C   . THR C 1 143 ? 299.093 264.359 116.536 1.00 14.69  ? 143 THR C C   1 
ATOM 4576 O O   . THR C 1 143 ? 299.025 263.929 117.690 1.00 14.69  ? 143 THR C O   1 
ATOM 4577 C CB  . THR C 1 143 ? 300.214 266.558 116.254 1.00 14.69  ? 143 THR C CB  1 
ATOM 4578 O OG1 . THR C 1 143 ? 301.250 267.228 115.536 1.00 14.69  ? 143 THR C OG1 1 
ATOM 4579 C CG2 . THR C 1 143 ? 300.331 266.894 117.698 1.00 14.69  ? 143 THR C CG2 1 
ATOM 4580 N N   . ALA C 1 144 ? 298.084 264.245 115.679 1.00 14.13  ? 144 ALA C N   1 
ATOM 4581 C CA  . ALA C 1 144 ? 296.847 263.599 116.085 1.00 14.13  ? 144 ALA C CA  1 
ATOM 4582 C C   . ALA C 1 144 ? 297.026 262.099 116.177 1.00 14.13  ? 144 ALA C C   1 
ATOM 4583 O O   . ALA C 1 144 ? 296.591 261.471 117.148 1.00 14.13  ? 144 ALA C O   1 
ATOM 4584 C CB  . ALA C 1 144 ? 295.735 263.944 115.105 1.00 14.13  ? 144 ALA C CB  1 
ATOM 4585 N N   . SER C 1 145 ? 297.673 261.505 115.175 1.00 19.96  ? 145 SER C N   1 
ATOM 4586 C CA  . SER C 1 145 ? 297.866 260.064 115.172 1.00 19.96  ? 145 SER C CA  1 
ATOM 4587 C C   . SER C 1 145 ? 298.917 259.616 116.171 1.00 19.96  ? 145 SER C C   1 
ATOM 4588 O O   . SER C 1 145 ? 298.922 258.448 116.553 1.00 19.96  ? 145 SER C O   1 
ATOM 4589 C CB  . SER C 1 145 ? 298.244 259.588 113.775 1.00 19.96  ? 145 SER C CB  1 
ATOM 4590 O OG  . SER C 1 145 ? 299.608 259.823 113.513 1.00 19.96  ? 145 SER C OG  1 
ATOM 4591 N N   . ALA C 1 146 ? 299.802 260.503 116.607 1.00 18.27  ? 146 ALA C N   1 
ATOM 4592 C CA  . ALA C 1 146 ? 300.806 260.110 117.577 1.00 18.27  ? 146 ALA C CA  1 
ATOM 4593 C C   . ALA C 1 146 ? 300.322 260.185 119.010 1.00 18.27  ? 146 ALA C C   1 
ATOM 4594 O O   . ALA C 1 146 ? 301.033 259.730 119.902 1.00 18.27  ? 146 ALA C O   1 
ATOM 4595 C CB  . ALA C 1 146 ? 302.038 260.991 117.424 1.00 18.27  ? 146 ALA C CB  1 
ATOM 4596 N N   . LEU C 1 147 ? 299.154 260.753 119.264 1.00 13.77  ? 147 LEU C N   1 
ATOM 4597 C CA  . LEU C 1 147 ? 298.749 261.057 120.626 1.00 13.77  ? 147 LEU C CA  1 
ATOM 4598 C C   . LEU C 1 147 ? 297.349 260.611 120.993 1.00 13.77  ? 147 LEU C C   1 
ATOM 4599 O O   . LEU C 1 147 ? 297.104 260.362 122.178 1.00 13.77  ? 147 LEU C O   1 
ATOM 4600 C CB  . LEU C 1 147 ? 298.843 262.564 120.878 1.00 13.77  ? 147 LEU C CB  1 
ATOM 4601 C CG  . LEU C 1 147 ? 300.191 263.150 121.245 1.00 13.77  ? 147 LEU C CG  1 
ATOM 4602 C CD1 . LEU C 1 147 ? 300.259 264.549 120.722 1.00 13.77  ? 147 LEU C CD1 1 
ATOM 4603 C CD2 . LEU C 1 147 ? 300.330 263.140 122.739 1.00 13.77  ? 147 LEU C CD2 1 
ATOM 4604 N N   . TYR C 1 148 ? 296.420 260.517 120.037 1.00 13.50  ? 148 TYR C N   1 
ATOM 4605 C CA  . TYR C 1 148 ? 295.038 260.162 120.335 1.00 13.50  ? 148 TYR C CA  1 
ATOM 4606 C C   . TYR C 1 148 ? 294.516 259.071 119.419 1.00 13.50  ? 148 TYR C C   1 
ATOM 4607 O O   . TYR C 1 148 ? 293.303 258.938 119.277 1.00 13.50  ? 148 TYR C O   1 
ATOM 4608 C CB  . TYR C 1 148 ? 294.127 261.382 120.236 1.00 13.50  ? 148 TYR C CB  1 
ATOM 4609 C CG  . TYR C 1 148 ? 294.565 262.510 121.112 1.00 13.50  ? 148 TYR C CG  1 
ATOM 4610 C CD1 . TYR C 1 148 ? 294.289 262.498 122.464 1.00 13.50  ? 148 TYR C CD1 1 
ATOM 4611 C CD2 . TYR C 1 148 ? 295.271 263.579 120.590 1.00 13.50  ? 148 TYR C CD2 1 
ATOM 4612 C CE1 . TYR C 1 148 ? 294.701 263.510 123.266 1.00 13.50  ? 148 TYR C CE1 1 
ATOM 4613 C CE2 . TYR C 1 148 ? 295.686 264.590 121.387 1.00 13.50  ? 148 TYR C CE2 1 
ATOM 4614 C CZ  . TYR C 1 148 ? 295.396 264.548 122.722 1.00 13.50  ? 148 TYR C CZ  1 
ATOM 4615 O OH  . TYR C 1 148 ? 295.807 265.562 123.532 1.00 13.50  ? 148 TYR C OH  1 
ATOM 4616 N N   . ARG C 1 149 ? 295.401 258.280 118.817 1.00 21.59  ? 149 ARG C N   1 
ATOM 4617 C CA  . ARG C 1 149 ? 294.987 257.298 117.824 1.00 21.59  ? 149 ARG C CA  1 
ATOM 4618 C C   . ARG C 1 149 ? 294.172 256.178 118.433 1.00 21.59  ? 149 ARG C C   1 
ATOM 4619 O O   . ARG C 1 149 ? 293.321 255.600 117.757 1.00 21.59  ? 149 ARG C O   1 
ATOM 4620 C CB  . ARG C 1 149 ? 296.205 256.720 117.135 1.00 21.59  ? 149 ARG C CB  1 
ATOM 4621 C CG  . ARG C 1 149 ? 295.927 256.021 115.851 1.00 21.59  ? 149 ARG C CG  1 
ATOM 4622 C CD  . ARG C 1 149 ? 297.208 255.451 115.313 1.00 21.59  ? 149 ARG C CD  1 
ATOM 4623 N NE  . ARG C 1 149 ? 297.089 255.043 113.925 1.00 21.59  ? 149 ARG C NE  1 
ATOM 4624 C CZ  . ARG C 1 149 ? 297.991 254.308 113.293 1.00 21.59  ? 149 ARG C CZ  1 
ATOM 4625 N NH1 . ARG C 1 149 ? 299.083 253.905 113.926 1.00 21.59  ? 149 ARG C NH1 1 
ATOM 4626 N NH2 . ARG C 1 149 ? 297.800 253.979 112.026 1.00 21.59  ? 149 ARG C NH2 1 
ATOM 4627 N N   . GLU C 1 150 ? 294.397 255.859 119.696 1.00 19.69  ? 150 GLU C N   1 
ATOM 4628 C CA  . GLU C 1 150 ? 293.644 254.800 120.342 1.00 19.69  ? 150 GLU C CA  1 
ATOM 4629 C C   . GLU C 1 150 ? 292.372 255.307 120.988 1.00 19.69  ? 150 GLU C C   1 
ATOM 4630 O O   . GLU C 1 150 ? 291.685 254.536 121.659 1.00 19.69  ? 150 GLU C O   1 
ATOM 4631 C CB  . GLU C 1 150 ? 294.515 254.087 121.374 1.00 19.69  ? 150 GLU C CB  1 
ATOM 4632 C CG  . GLU C 1 150 ? 295.903 253.717 120.856 1.00 19.69  ? 150 GLU C CG  1 
ATOM 4633 C CD  . GLU C 1 150 ? 295.868 252.950 119.547 1.00 19.69  ? 150 GLU C CD  1 
ATOM 4634 O OE1 . GLU C 1 150 ? 295.165 251.925 119.478 1.00 19.69  ? 150 GLU C OE1 1 
ATOM 4635 O OE2 . GLU C 1 150 ? 296.537 253.371 118.583 1.00 19.69  ? 150 GLU C OE2 1 
ATOM 4636 N N   . ALA C 1 151 ? 292.052 256.587 120.816 1.00 13.80  ? 151 ALA C N   1 
ATOM 4637 C CA  . ALA C 1 151 ? 290.745 257.119 121.154 1.00 13.80  ? 151 ALA C CA  1 
ATOM 4638 C C   . ALA C 1 151 ? 290.019 257.695 119.957 1.00 13.80  ? 151 ALA C C   1 
ATOM 4639 O O   . ALA C 1 151 ? 288.790 257.733 119.967 1.00 13.80  ? 151 ALA C O   1 
ATOM 4640 C CB  . ALA C 1 151 ? 290.855 258.197 122.239 1.00 13.80  ? 151 ALA C CB  1 
ATOM 4641 N N   . LEU C 1 152 ? 290.735 258.096 118.919 1.00 15.57  ? 152 LEU C N   1 
ATOM 4642 C CA  . LEU C 1 152 ? 290.154 258.452 117.636 1.00 15.57  ? 152 LEU C CA  1 
ATOM 4643 C C   . LEU C 1 152 ? 289.813 257.250 116.790 1.00 15.57  ? 152 LEU C C   1 
ATOM 4644 O O   . LEU C 1 152 ? 289.516 257.412 115.607 1.00 15.57  ? 152 LEU C O   1 
ATOM 4645 C CB  . LEU C 1 152 ? 291.117 259.328 116.848 1.00 15.57  ? 152 LEU C CB  1 
ATOM 4646 C CG  . LEU C 1 152 ? 290.902 260.817 116.745 1.00 15.57  ? 152 LEU C CG  1 
ATOM 4647 C CD1 . LEU C 1 152 ? 290.846 261.407 118.086 1.00 15.57  ? 152 LEU C CD1 1 
ATOM 4648 C CD2 . LEU C 1 152 ? 292.085 261.347 116.030 1.00 15.57  ? 152 LEU C CD2 1 
ATOM 4649 N N   . GLU C 1 153 ? 289.907 256.049 117.337 1.00 17.77  ? 153 GLU C N   1 
ATOM 4650 C CA  . GLU C 1 153 ? 289.589 254.844 116.591 1.00 17.77  ? 153 GLU C CA  1 
ATOM 4651 C C   . GLU C 1 153 ? 288.774 253.876 117.428 1.00 17.77  ? 153 GLU C C   1 
ATOM 4652 O O   . GLU C 1 153 ? 288.572 252.737 117.004 1.00 17.77  ? 153 GLU C O   1 
ATOM 4653 C CB  . GLU C 1 153 ? 290.862 254.161 116.103 1.00 17.77  ? 153 GLU C CB  1 
ATOM 4654 C CG  . GLU C 1 153 ? 291.529 254.857 114.948 1.00 17.77  ? 153 GLU C CG  1 
ATOM 4655 C CD  . GLU C 1 153 ? 292.538 253.987 114.264 1.00 17.77  ? 153 GLU C CD  1 
ATOM 4656 O OE1 . GLU C 1 153 ? 292.944 252.974 114.866 1.00 17.77  ? 153 GLU C OE1 1 
ATOM 4657 O OE2 . GLU C 1 153 ? 292.926 254.310 113.125 1.00 17.77  ? 153 GLU C OE2 1 
ATOM 4658 N N   . SER C 1 154 ? 288.304 254.290 118.586 1.00 17.72  ? 154 SER C N   1 
ATOM 4659 C CA  . SER C 1 154 ? 287.618 253.425 119.514 1.00 17.72  ? 154 SER C CA  1 
ATOM 4660 C C   . SER C 1 154 ? 286.133 253.742 119.549 1.00 17.72  ? 154 SER C C   1 
ATOM 4661 O O   . SER C 1 154 ? 285.719 254.854 119.214 1.00 17.72  ? 154 SER C O   1 
ATOM 4662 C CB  . SER C 1 154 ? 288.213 253.585 120.914 1.00 17.72  ? 154 SER C CB  1 
ATOM 4663 O OG  . SER C 1 154 ? 287.532 254.593 121.616 1.00 17.72  ? 154 SER C OG  1 
ATOM 4664 N N   . PRO C 1 155 ? 285.292 252.783 119.931 1.00 17.80  ? 155 PRO C N   1 
ATOM 4665 C CA  . PRO C 1 155 ? 283.849 253.062 120.031 1.00 17.80  ? 155 PRO C CA  1 
ATOM 4666 C C   . PRO C 1 155 ? 283.450 253.775 121.317 1.00 17.80  ? 155 PRO C C   1 
ATOM 4667 O O   . PRO C 1 155 ? 282.753 253.236 122.177 1.00 17.80  ? 155 PRO C O   1 
ATOM 4668 C CB  . PRO C 1 155 ? 283.242 251.659 119.941 1.00 17.80  ? 155 PRO C CB  1 
ATOM 4669 C CG  . PRO C 1 155 ? 284.312 250.801 119.399 1.00 17.80  ? 155 PRO C CG  1 
ATOM 4670 C CD  . PRO C 1 155 ? 285.542 251.337 119.978 1.00 17.80  ? 155 PRO C CD  1 
ATOM 4671 N N   . GLU C 1 156 ? 283.888 255.020 121.469 1.00 23.86  ? 156 GLU C N   1 
ATOM 4672 C CA  . GLU C 1 156 ? 283.370 255.880 122.519 1.00 23.86  ? 156 GLU C CA  1 
ATOM 4673 C C   . GLU C 1 156 ? 283.244 257.299 121.997 1.00 23.86  ? 156 GLU C C   1 
ATOM 4674 O O   . GLU C 1 156 ? 283.972 257.714 121.096 1.00 23.86  ? 156 GLU C O   1 
ATOM 4675 C CB  . GLU C 1 156 ? 284.248 255.943 123.780 1.00 23.86  ? 156 GLU C CB  1 
ATOM 4676 C CG  . GLU C 1 156 ? 284.293 254.726 124.672 1.00 23.86  ? 156 GLU C CG  1 
ATOM 4677 C CD  . GLU C 1 156 ? 285.472 253.836 124.381 1.00 23.86  ? 156 GLU C CD  1 
ATOM 4678 O OE1 . GLU C 1 156 ? 286.276 254.190 123.498 1.00 23.86  ? 156 GLU C OE1 1 
ATOM 4679 O OE2 . GLU C 1 156 ? 285.611 252.794 125.058 1.00 23.86  ? 156 GLU C OE2 1 
ATOM 4680 N N   . HIS C 1 157 ? 282.304 258.038 122.576 1.00 22.95  ? 157 HIS C N   1 
ATOM 4681 C CA  . HIS C 1 157 ? 282.358 259.491 122.559 1.00 22.95  ? 157 HIS C CA  1 
ATOM 4682 C C   . HIS C 1 157 ? 283.131 259.847 123.807 1.00 22.95  ? 157 HIS C C   1 
ATOM 4683 O O   . HIS C 1 157 ? 282.553 259.945 124.893 1.00 22.95  ? 157 HIS C O   1 
ATOM 4684 C CB  . HIS C 1 157 ? 280.982 260.133 122.622 1.00 22.95  ? 157 HIS C CB  1 
ATOM 4685 C CG  . HIS C 1 157 ? 279.971 259.507 121.729 1.00 22.95  ? 157 HIS C CG  1 
ATOM 4686 N ND1 . HIS C 1 157 ? 278.960 258.709 122.211 1.00 22.95  ? 157 HIS C ND1 1 
ATOM 4687 C CD2 . HIS C 1 157 ? 279.817 259.549 120.388 1.00 22.95  ? 157 HIS C CD2 1 
ATOM 4688 C CE1 . HIS C 1 157 ? 278.217 258.295 121.205 1.00 22.95  ? 157 HIS C CE1 1 
ATOM 4689 N NE2 . HIS C 1 157 ? 278.720 258.785 120.088 1.00 22.95  ? 157 HIS C NE2 1 
ATOM 4690 N N   . CYS C 1 158 ? 284.442 259.993 123.682 1.00 20.74  ? 158 CYS C N   1 
ATOM 4691 C CA  . CYS C 1 158 ? 285.195 260.366 124.866 1.00 20.74  ? 158 CYS C CA  1 
ATOM 4692 C C   . CYS C 1 158 ? 284.958 261.829 125.206 1.00 20.74  ? 158 CYS C C   1 
ATOM 4693 O O   . CYS C 1 158 ? 284.857 262.190 126.383 1.00 20.74  ? 158 CYS C O   1 
ATOM 4694 C CB  . CYS C 1 158 ? 286.671 260.072 124.648 1.00 20.74  ? 158 CYS C CB  1 
ATOM 4695 S SG  . CYS C 1 158 ? 286.982 258.576 123.691 1.00 20.74  ? 158 CYS C SG  1 
ATOM 4696 N N   . SER C 1 159 ? 284.797 262.659 124.187 1.00 12.74  ? 159 SER C N   1 
ATOM 4697 C CA  . SER C 1 159 ? 284.605 264.094 124.324 1.00 12.74  ? 159 SER C CA  1 
ATOM 4698 C C   . SER C 1 159 ? 284.139 264.623 122.980 1.00 12.74  ? 159 SER C C   1 
ATOM 4699 O O   . SER C 1 159 ? 284.355 263.972 121.962 1.00 12.74  ? 159 SER C O   1 
ATOM 4700 C CB  . SER C 1 159 ? 285.906 264.790 124.749 1.00 12.74  ? 159 SER C CB  1 
ATOM 4701 O OG  . SER C 1 159 ? 286.994 264.300 123.997 1.00 12.74  ? 159 SER C OG  1 
ATOM 4702 N N   . PRO C 1 160 ? 283.492 265.791 122.953 1.00 12.98  ? 160 PRO C N   1 
ATOM 4703 C CA  . PRO C 1 160 ? 283.142 266.406 121.665 1.00 12.98  ? 160 PRO C CA  1 
ATOM 4704 C C   . PRO C 1 160 ? 284.329 266.776 120.810 1.00 12.98  ? 160 PRO C C   1 
ATOM 4705 O O   . PRO C 1 160 ? 284.171 266.933 119.593 1.00 12.98  ? 160 PRO C O   1 
ATOM 4706 C CB  . PRO C 1 160 ? 282.364 267.651 122.081 1.00 12.98  ? 160 PRO C CB  1 
ATOM 4707 C CG  . PRO C 1 160 ? 281.828 267.331 123.385 1.00 12.98  ? 160 PRO C CG  1 
ATOM 4708 C CD  . PRO C 1 160 ? 282.788 266.444 124.066 1.00 12.98  ? 160 PRO C CD  1 
ATOM 4709 N N   . HIS C 1 161 ? 285.513 266.917 121.402 1.00 10.98  ? 161 HIS C N   1 
ATOM 4710 C CA  . HIS C 1 161 ? 286.699 267.217 120.619 1.00 10.98  ? 161 HIS C CA  1 
ATOM 4711 C C   . HIS C 1 161 ? 287.125 266.022 119.792 1.00 10.98  ? 161 HIS C C   1 
ATOM 4712 O O   . HIS C 1 161 ? 287.550 266.184 118.647 1.00 10.98  ? 161 HIS C O   1 
ATOM 4713 C CB  . HIS C 1 161 ? 287.814 267.666 121.538 1.00 10.98  ? 161 HIS C CB  1 
ATOM 4714 C CG  . HIS C 1 161 ? 287.586 269.014 122.125 1.00 10.98  ? 161 HIS C CG  1 
ATOM 4715 N ND1 . HIS C 1 161 ? 287.257 269.203 123.446 1.00 10.98  ? 161 HIS C ND1 1 
ATOM 4716 C CD2 . HIS C 1 161 ? 287.628 270.242 121.565 1.00 10.98  ? 161 HIS C CD2 1 
ATOM 4717 C CE1 . HIS C 1 161 ? 287.113 270.492 123.677 1.00 10.98  ? 161 HIS C CE1 1 
ATOM 4718 N NE2 . HIS C 1 161 ? 287.335 271.145 122.553 1.00 10.98  ? 161 HIS C NE2 1 
ATOM 4719 N N   . HIS C 1 162 ? 286.984 264.813 120.338 1.00 9.88   ? 162 HIS C N   1 
ATOM 4720 C CA  . HIS C 1 162 ? 287.209 263.614 119.541 1.00 9.88   ? 162 HIS C CA  1 
ATOM 4721 C C   . HIS C 1 162 ? 286.175 263.491 118.435 1.00 9.88   ? 162 HIS C C   1 
ATOM 4722 O O   . HIS C 1 162 ? 286.513 263.141 117.299 1.00 9.88   ? 162 HIS C O   1 
ATOM 4723 C CB  . HIS C 1 162 ? 287.159 262.374 120.420 1.00 9.88   ? 162 HIS C CB  1 
ATOM 4724 C CG  . HIS C 1 162 ? 288.279 262.266 121.403 1.00 9.88   ? 162 HIS C CG  1 
ATOM 4725 N ND1 . HIS C 1 162 ? 288.094 262.428 122.756 1.00 9.88   ? 162 HIS C ND1 1 
ATOM 4726 C CD2 . HIS C 1 162 ? 289.587 261.986 121.235 1.00 9.88   ? 162 HIS C CD2 1 
ATOM 4727 C CE1 . HIS C 1 162 ? 289.242 262.253 123.379 1.00 9.88   ? 162 HIS C CE1 1 
ATOM 4728 N NE2 . HIS C 1 162 ? 290.166 261.987 122.477 1.00 9.88   ? 162 HIS C NE2 1 
ATOM 4729 N N   . THR C 1 163 ? 284.911 263.787 118.751 1.00 11.19  ? 163 THR C N   1 
ATOM 4730 C CA  . THR C 1 163 ? 283.830 263.598 117.796 1.00 11.19  ? 163 THR C CA  1 
ATOM 4731 C C   . THR C 1 163 ? 283.930 264.585 116.649 1.00 11.19  ? 163 THR C C   1 
ATOM 4732 O O   . THR C 1 163 ? 283.518 264.269 115.536 1.00 11.19  ? 163 THR C O   1 
ATOM 4733 C CB  . THR C 1 163 ? 282.473 263.729 118.489 1.00 11.19  ? 163 THR C CB  1 
ATOM 4734 O OG1 . THR C 1 163 ? 282.507 263.054 119.745 1.00 11.19  ? 163 THR C OG1 1 
ATOM 4735 C CG2 . THR C 1 163 ? 281.399 263.071 117.675 1.00 11.19  ? 163 THR C CG2 1 
ATOM 4736 N N   . ALA C 1 164 ? 284.486 265.769 116.890 1.00 10.61  ? 164 ALA C N   1 
ATOM 4737 C CA  . ALA C 1 164 ? 284.741 266.707 115.804 1.00 10.61  ? 164 ALA C CA  1 
ATOM 4738 C C   . ALA C 1 164 ? 286.059 266.444 115.095 1.00 10.61  ? 164 ALA C C   1 
ATOM 4739 O O   . ALA C 1 164 ? 286.178 266.706 113.890 1.00 10.61  ? 164 ALA C O   1 
ATOM 4740 C CB  . ALA C 1 164 ? 284.728 268.132 116.337 1.00 10.61  ? 164 ALA C CB  1 
ATOM 4741 N N   . LEU C 1 165 ? 287.040 265.902 115.816 1.00 10.94  ? 165 LEU C N   1 
ATOM 4742 C CA  . LEU C 1 165 ? 288.337 265.586 115.239 1.00 10.94  ? 165 LEU C CA  1 
ATOM 4743 C C   . LEU C 1 165 ? 288.239 264.458 114.223 1.00 10.94  ? 165 LEU C C   1 
ATOM 4744 O O   . LEU C 1 165 ? 288.920 264.489 113.189 1.00 10.94  ? 165 LEU C O   1 
ATOM 4745 C CB  . LEU C 1 165 ? 289.293 265.217 116.366 1.00 10.94  ? 165 LEU C CB  1 
ATOM 4746 C CG  . LEU C 1 165 ? 290.786 265.379 116.157 1.00 10.94  ? 165 LEU C CG  1 
ATOM 4747 C CD1 . LEU C 1 165 ? 291.051 266.708 115.551 1.00 10.94  ? 165 LEU C CD1 1 
ATOM 4748 C CD2 . LEU C 1 165 ? 291.494 265.248 117.482 1.00 10.94  ? 165 LEU C CD2 1 
ATOM 4749 N N   . ARG C 1 166 ? 287.390 263.463 114.500 1.00 8.93   ? 166 ARG C N   1 
ATOM 4750 C CA  . ARG C 1 166 ? 287.204 262.350 113.574 1.00 8.93   ? 166 ARG C CA  1 
ATOM 4751 C C   . ARG C 1 166 ? 286.633 262.827 112.249 1.00 8.93   ? 166 ARG C C   1 
ATOM 4752 O O   . ARG C 1 166 ? 287.137 262.468 111.180 1.00 8.93   ? 166 ARG C O   1 
ATOM 4753 C CB  . ARG C 1 166 ? 286.291 261.298 114.190 1.00 8.93   ? 166 ARG C CB  1 
ATOM 4754 C CG  . ARG C 1 166 ? 286.870 260.547 115.341 1.00 8.93   ? 166 ARG C CG  1 
ATOM 4755 C CD  . ARG C 1 166 ? 285.794 259.824 116.086 1.00 8.93   ? 166 ARG C CD  1 
ATOM 4756 N NE  . ARG C 1 166 ? 286.320 259.047 117.195 1.00 8.93   ? 166 ARG C NE  1 
ATOM 4757 C CZ  . ARG C 1 166 ? 285.830 259.088 118.424 1.00 8.93   ? 166 ARG C CZ  1 
ATOM 4758 N NH1 . ARG C 1 166 ? 284.809 259.863 118.704 1.00 8.93   ? 166 ARG C NH1 1 
ATOM 4759 N NH2 . ARG C 1 166 ? 286.364 258.360 119.378 1.00 8.93   ? 166 ARG C NH2 1 
ATOM 4760 N N   . GLN C 1 167 ? 285.602 263.669 112.301 1.00 12.31  ? 167 GLN C N   1 
ATOM 4761 C CA  . GLN C 1 167 ? 284.977 264.149 111.077 1.00 12.31  ? 167 GLN C CA  1 
ATOM 4762 C C   . GLN C 1 167 ? 285.877 265.111 110.331 1.00 12.31  ? 167 GLN C C   1 
ATOM 4763 O O   . GLN C 1 167 ? 285.855 265.128 109.098 1.00 12.31  ? 167 GLN C O   1 
ATOM 4764 C CB  . GLN C 1 167 ? 283.647 264.818 111.384 1.00 12.31  ? 167 GLN C CB  1 
ATOM 4765 C CG  . GLN C 1 167 ? 282.833 264.120 112.436 1.00 12.31  ? 167 GLN C CG  1 
ATOM 4766 C CD  . GLN C 1 167 ? 282.163 262.877 111.932 1.00 12.31  ? 167 GLN C CD  1 
ATOM 4767 O OE1 . GLN C 1 167 ? 281.585 262.869 110.849 1.00 12.31  ? 167 GLN C OE1 1 
ATOM 4768 N NE2 . GLN C 1 167 ? 282.225 261.815 112.717 1.00 12.31  ? 167 GLN C NE2 1 
ATOM 4769 N N   . ALA C 1 168 ? 286.696 265.887 111.048 1.00 28.56  ? 168 ALA C N   1 
ATOM 4770 C CA  . ALA C 1 168 ? 287.664 266.749 110.378 1.00 28.56  ? 168 ALA C CA  1 
ATOM 4771 C C   . ALA C 1 168 ? 288.710 265.937 109.626 1.00 28.56  ? 168 ALA C C   1 
ATOM 4772 O O   . ALA C 1 168 ? 289.037 266.250 108.472 1.00 28.56  ? 168 ALA C O   1 
ATOM 4773 C CB  . ALA C 1 168 ? 288.330 267.661 111.396 1.00 28.56  ? 168 ALA C CB  1 
ATOM 4774 N N   . ILE C 1 169 ? 289.211 264.864 110.247 1.00 12.58  ? 169 ILE C N   1 
ATOM 4775 C CA  . ILE C 1 169 ? 290.213 264.016 109.607 1.00 12.58  ? 169 ILE C CA  1 
ATOM 4776 C C   . ILE C 1 169 ? 289.632 263.303 108.392 1.00 12.58  ? 169 ILE C C   1 
ATOM 4777 O O   . ILE C 1 169 ? 290.265 263.245 107.330 1.00 12.58  ? 169 ILE C O   1 
ATOM 4778 C CB  . ILE C 1 169 ? 290.780 263.021 110.629 1.00 12.58  ? 169 ILE C CB  1 
ATOM 4779 C CG1 . ILE C 1 169 ? 291.696 263.742 111.589 1.00 12.58  ? 169 ILE C CG1 1 
ATOM 4780 C CG2 . ILE C 1 169 ? 291.562 261.922 109.959 1.00 12.58  ? 169 ILE C CG2 1 
ATOM 4781 C CD1 . ILE C 1 169 ? 292.100 262.910 112.714 1.00 12.58  ? 169 ILE C CD1 1 
ATOM 4782 N N   . LEU C 1 170 ? 288.407 262.787 108.509 1.00 13.47  ? 170 LEU C N   1 
ATOM 4783 C CA  . LEU C 1 170 ? 287.821 262.074 107.378 1.00 13.47  ? 170 LEU C CA  1 
ATOM 4784 C C   . LEU C 1 170 ? 287.427 263.017 106.254 1.00 13.47  ? 170 LEU C C   1 
ATOM 4785 O O   . LEU C 1 170 ? 287.477 262.627 105.082 1.00 13.47  ? 170 LEU C O   1 
ATOM 4786 C CB  . LEU C 1 170 ? 286.622 261.256 107.828 1.00 13.47  ? 170 LEU C CB  1 
ATOM 4787 C CG  . LEU C 1 170 ? 286.969 260.171 108.840 1.00 13.47  ? 170 LEU C CG  1 
ATOM 4788 C CD1 . LEU C 1 170 ? 285.769 259.856 109.684 1.00 13.47  ? 170 LEU C CD1 1 
ATOM 4789 C CD2 . LEU C 1 170 ? 287.473 258.944 108.145 1.00 13.47  ? 170 LEU C CD2 1 
ATOM 4790 N N   . ALA C 1 171 ? 287.067 264.261 106.580 1.00 15.68  ? 171 ALA C N   1 
ATOM 4791 C CA  . ALA C 1 171 ? 286.803 265.252 105.545 1.00 15.68  ? 171 ALA C CA  1 
ATOM 4792 C C   . ALA C 1 171 ? 288.071 265.606 104.789 1.00 15.68  ? 171 ALA C C   1 
ATOM 4793 O O   . ALA C 1 171 ? 288.052 265.758 103.560 1.00 15.68  ? 171 ALA C O   1 
ATOM 4794 C CB  . ALA C 1 171 ? 286.191 266.498 106.171 1.00 15.68  ? 171 ALA C CB  1 
ATOM 4795 N N   . TRP C 1 172 ? 289.192 265.710 105.506 1.00 20.20  ? 172 TRP C N   1 
ATOM 4796 C CA  . TRP C 1 172 ? 290.463 265.908 104.824 1.00 20.20  ? 172 TRP C CA  1 
ATOM 4797 C C   . TRP C 1 172 ? 290.850 264.698 103.988 1.00 20.20  ? 172 TRP C C   1 
ATOM 4798 O O   . TRP C 1 172 ? 291.465 264.852 102.928 1.00 20.20  ? 172 TRP C O   1 
ATOM 4799 C CB  . TRP C 1 172 ? 291.564 266.231 105.828 1.00 20.20  ? 172 TRP C CB  1 
ATOM 4800 C CG  . TRP C 1 172 ? 292.843 266.553 105.158 1.00 20.20  ? 172 TRP C CG  1 
ATOM 4801 C CD1 . TRP C 1 172 ? 293.981 265.824 105.191 1.00 20.20  ? 172 TRP C CD1 1 
ATOM 4802 C CD2 . TRP C 1 172 ? 293.112 267.680 104.322 1.00 20.20  ? 172 TRP C CD2 1 
ATOM 4803 N NE1 . TRP C 1 172 ? 294.948 266.422 104.432 1.00 20.20  ? 172 TRP C NE1 1 
ATOM 4804 C CE2 . TRP C 1 172 ? 294.434 267.566 103.888 1.00 20.20  ? 172 TRP C CE2 1 
ATOM 4805 C CE3 . TRP C 1 172 ? 292.361 268.777 103.903 1.00 20.20  ? 172 TRP C CE3 1 
ATOM 4806 C CZ2 . TRP C 1 172 ? 295.021 268.502 103.065 1.00 20.20  ? 172 TRP C CZ2 1 
ATOM 4807 C CZ3 . TRP C 1 172 ? 292.942 269.695 103.088 1.00 20.20  ? 172 TRP C CZ3 1 
ATOM 4808 C CH2 . TRP C 1 172 ? 294.258 269.557 102.674 1.00 20.20  ? 172 TRP C CH2 1 
ATOM 4809 N N   . GLY C 1 173 ? 290.483 263.499 104.433 1.00 24.83  ? 173 GLY C N   1 
ATOM 4810 C CA  . GLY C 1 173 ? 290.733 262.311 103.632 1.00 24.83  ? 173 GLY C CA  1 
ATOM 4811 C C   . GLY C 1 173 ? 289.962 262.302 102.326 1.00 24.83  ? 173 GLY C C   1 
ATOM 4812 O O   . GLY C 1 173 ? 290.512 261.959 101.276 1.00 24.83  ? 173 GLY C O   1 
ATOM 4813 N N   . GLU C 1 174 ? 288.683 262.692 102.374 1.00 29.45  ? 174 GLU C N   1 
ATOM 4814 C CA  . GLU C 1 174 ? 287.892 262.823 101.150 1.00 29.45  ? 174 GLU C CA  1 
ATOM 4815 C C   . GLU C 1 174 ? 288.468 263.891 100.227 1.00 29.45  ? 174 GLU C C   1 
ATOM 4816 O O   . GLU C 1 174 ? 288.507 263.709 99.003  1.00 29.45  ? 174 GLU C O   1 
ATOM 4817 C CB  . GLU C 1 174 ? 286.439 263.156 101.482 1.00 29.45  ? 174 GLU C CB  1 
ATOM 4818 C CG  . GLU C 1 174 ? 285.626 262.041 102.115 1.00 29.45  ? 174 GLU C CG  1 
ATOM 4819 C CD  . GLU C 1 174 ? 284.227 262.506 102.526 1.00 29.45  ? 174 GLU C CD  1 
ATOM 4820 O OE1 . GLU C 1 174 ? 283.716 263.470 101.918 1.00 29.45  ? 174 GLU C OE1 1 
ATOM 4821 O OE2 . GLU C 1 174 ? 283.638 261.916 103.459 1.00 29.45  ? 174 GLU C OE2 1 
ATOM 4822 N N   . LEU C 1 175 ? 288.954 264.996 100.804 1.00 29.43  ? 175 LEU C N   1 
ATOM 4823 C CA  . LEU C 1 175 ? 289.526 266.071 99.997  1.00 29.43  ? 175 LEU C CA  1 
ATOM 4824 C C   . LEU C 1 175 ? 290.810 265.638 99.304  1.00 29.43  ? 175 LEU C C   1 
ATOM 4825 O O   . LEU C 1 175 ? 291.011 265.927 98.119  1.00 29.43  ? 175 LEU C O   1 
ATOM 4826 C CB  . LEU C 1 175 ? 289.780 267.295 100.867 1.00 29.43  ? 175 LEU C CB  1 
ATOM 4827 C CG  . LEU C 1 175 ? 288.679 268.346 100.790 1.00 29.43  ? 175 LEU C CG  1 
ATOM 4828 C CD1 . LEU C 1 175 ? 288.908 269.435 101.804 1.00 29.43  ? 175 LEU C CD1 1 
ATOM 4829 C CD2 . LEU C 1 175 ? 288.617 268.921 99.397  1.00 29.43  ? 175 LEU C CD2 1 
ATOM 4830 N N   . MET C 1 176 ? 291.677 264.916 100.009 1.00 34.84  ? 176 MET C N   1 
ATOM 4831 C CA  . MET C 1 176 ? 292.910 264.469 99.373  1.00 34.84  ? 176 MET C CA  1 
ATOM 4832 C C   . MET C 1 176 ? 292.661 263.348 98.373  1.00 34.84  ? 176 MET C C   1 
ATOM 4833 O O   . MET C 1 176 ? 293.382 263.248 97.373  1.00 34.84  ? 176 MET C O   1 
ATOM 4834 C CB  . MET C 1 176 ? 293.925 264.035 100.422 1.00 34.84  ? 176 MET C CB  1 
ATOM 4835 C CG  . MET C 1 176 ? 294.645 265.186 101.090 1.00 34.84  ? 176 MET C CG  1 
ATOM 4836 S SD  . MET C 1 176 ? 294.771 266.646 100.041 1.00 34.84  ? 176 MET C SD  1 
ATOM 4837 C CE  . MET C 1 176 ? 296.203 266.251 99.045  1.00 34.84  ? 176 MET C CE  1 
ATOM 4838 N N   . THR C 1 177 ? 291.643 262.513 98.608  1.00 32.06  ? 177 THR C N   1 
ATOM 4839 C CA  . THR C 1 177 ? 291.270 261.502 97.624  1.00 32.06  ? 177 THR C CA  1 
ATOM 4840 C C   . THR C 1 177 ? 290.768 262.150 96.343  1.00 32.06  ? 177 THR C C   1 
ATOM 4841 O O   . THR C 1 177 ? 291.103 261.705 95.239  1.00 32.06  ? 177 THR C O   1 
ATOM 4842 C CB  . THR C 1 177 ? 290.210 260.579 98.214  1.00 32.06  ? 177 THR C CB  1 
ATOM 4843 O OG1 . THR C 1 177 ? 290.710 259.998 99.424  1.00 32.06  ? 177 THR C OG1 1 
ATOM 4844 C CG2 . THR C 1 177 ? 289.871 259.466 97.248  1.00 32.06  ? 177 THR C CG2 1 
ATOM 4845 N N   . LEU C 1 178 ? 290.016 263.242 96.475  1.00 35.44  ? 178 LEU C N   1 
ATOM 4846 C CA  . LEU C 1 178 ? 289.612 264.014 95.306  1.00 35.44  ? 178 LEU C CA  1 
ATOM 4847 C C   . LEU C 1 178 ? 290.805 264.654 94.613  1.00 35.44  ? 178 LEU C C   1 
ATOM 4848 O O   . LEU C 1 178 ? 290.829 264.758 93.382  1.00 35.44  ? 178 LEU C O   1 
ATOM 4849 C CB  . LEU C 1 178 ? 288.608 265.078 95.723  1.00 35.44  ? 178 LEU C CB  1 
ATOM 4850 C CG  . LEU C 1 178 ? 288.349 266.293 94.846  1.00 35.44  ? 178 LEU C CG  1 
ATOM 4851 C CD1 . LEU C 1 178 ? 287.719 265.934 93.528  1.00 35.44  ? 178 LEU C CD1 1 
ATOM 4852 C CD2 . LEU C 1 178 ? 287.421 267.138 95.613  1.00 35.44  ? 178 LEU C CD2 1 
ATOM 4853 N N   . ALA C 1 179 ? 291.803 265.088 95.387  1.00 40.80  ? 179 ALA C N   1 
ATOM 4854 C CA  . ALA C 1 179 ? 293.002 265.676 94.793  1.00 40.80  ? 179 ALA C CA  1 
ATOM 4855 C C   . ALA C 1 179 ? 293.764 264.665 93.941  1.00 40.80  ? 179 ALA C C   1 
ATOM 4856 O O   . ALA C 1 179 ? 294.168 264.972 92.810  1.00 40.80  ? 179 ALA C O   1 
ATOM 4857 C CB  . ALA C 1 179 ? 293.903 266.235 95.888  1.00 40.80  ? 179 ALA C CB  1 
ATOM 4858 N N   . THR C 1 180 ? 293.940 263.445 94.454  1.00 48.34  ? 180 THR C N   1 
ATOM 4859 C CA  . THR C 1 180 ? 294.581 262.408 93.646  1.00 48.34  ? 180 THR C CA  1 
ATOM 4860 C C   . THR C 1 180 ? 293.699 261.956 92.490  1.00 48.34  ? 180 THR C C   1 
ATOM 4861 O O   . THR C 1 180 ? 294.221 261.473 91.481  1.00 48.34  ? 180 THR C O   1 
ATOM 4862 C CB  . THR C 1 180 ? 294.969 261.191 94.486  1.00 48.34  ? 180 THR C CB  1 
ATOM 4863 O OG1 . THR C 1 180 ? 293.802 260.419 94.785  1.00 48.34  ? 180 THR C OG1 1 
ATOM 4864 C CG2 . THR C 1 180 ? 295.670 261.600 95.759  1.00 48.34  ? 180 THR C CG2 1 
ATOM 4865 N N   . TRP C 1 181 ? 292.374 262.082 92.614  1.00 54.62  ? 181 TRP C N   1 
ATOM 4866 C CA  . TRP C 1 181 ? 291.511 261.773 91.478  1.00 54.62  ? 181 TRP C CA  1 
ATOM 4867 C C   . TRP C 1 181 ? 291.698 262.780 90.355  1.00 54.62  ? 181 TRP C C   1 
ATOM 4868 O O   . TRP C 1 181 ? 291.772 262.398 89.183  1.00 54.62  ? 181 TRP C O   1 
ATOM 4869 C CB  . TRP C 1 181 ? 290.046 261.740 91.904  1.00 54.62  ? 181 TRP C CB  1 
ATOM 4870 C CG  . TRP C 1 181 ? 289.107 261.289 90.814  1.00 54.62  ? 181 TRP C CG  1 
ATOM 4871 C CD1 . TRP C 1 181 ? 288.671 260.022 90.592  1.00 54.62  ? 181 TRP C CD1 1 
ATOM 4872 C CD2 . TRP C 1 181 ? 288.487 262.106 89.807  1.00 54.62  ? 181 TRP C CD2 1 
ATOM 4873 N NE1 . TRP C 1 181 ? 287.825 259.991 89.513  1.00 54.62  ? 181 TRP C NE1 1 
ATOM 4874 C CE2 . TRP C 1 181 ? 287.697 261.259 89.014  1.00 54.62  ? 181 TRP C CE2 1 
ATOM 4875 C CE3 . TRP C 1 181 ? 288.527 263.469 89.500  1.00 54.62  ? 181 TRP C CE3 1 
ATOM 4876 C CZ2 . TRP C 1 181 ? 286.958 261.726 87.938  1.00 54.62  ? 181 TRP C CZ2 1 
ATOM 4877 C CZ3 . TRP C 1 181 ? 287.795 263.930 88.430  1.00 54.62  ? 181 TRP C CZ3 1 
ATOM 4878 C CH2 . TRP C 1 181 ? 287.021 263.063 87.662  1.00 54.62  ? 181 TRP C CH2 1 
ATOM 4879 N N   . VAL C 1 182 ? 291.743 264.069 90.689  1.00 56.70  ? 182 VAL C N   1 
ATOM 4880 C CA  . VAL C 1 182 ? 291.879 265.093 89.659  1.00 56.70  ? 182 VAL C CA  1 
ATOM 4881 C C   . VAL C 1 182 ? 293.273 265.049 89.053  1.00 56.70  ? 182 VAL C C   1 
ATOM 4882 O O   . VAL C 1 182 ? 293.447 265.292 87.851  1.00 56.70  ? 182 VAL C O   1 
ATOM 4883 C CB  . VAL C 1 182 ? 291.536 266.477 90.242  1.00 56.70  ? 182 VAL C CB  1 
ATOM 4884 C CG1 . VAL C 1 182 ? 291.709 267.567 89.216  1.00 56.70  ? 182 VAL C CG1 1 
ATOM 4885 C CG2 . VAL C 1 182 ? 290.112 266.495 90.717  1.00 56.70  ? 182 VAL C CG2 1 
ATOM 4886 N N   . GLY C 1 183 ? 294.278 264.682 89.852  1.00 59.07  ? 183 GLY C N   1 
ATOM 4887 C CA  . GLY C 1 183 ? 295.610 264.488 89.301  1.00 59.07  ? 183 GLY C CA  1 
ATOM 4888 C C   . GLY C 1 183 ? 295.684 263.342 88.309  1.00 59.07  ? 183 GLY C C   1 
ATOM 4889 O O   . GLY C 1 183 ? 296.394 263.423 87.305  1.00 59.07  ? 183 GLY C O   1 
ATOM 4890 N N   . ASN C 1 184 ? 294.929 262.273 88.557  1.00 63.50  ? 184 ASN C N   1 
ATOM 4891 C CA  . ASN C 1 184 ? 294.954 261.087 87.710  1.00 63.50  ? 184 ASN C CA  1 
ATOM 4892 C C   . ASN C 1 184 ? 293.809 261.061 86.704  1.00 63.50  ? 184 ASN C C   1 
ATOM 4893 O O   . ASN C 1 184 ? 293.383 259.983 86.277  1.00 63.50  ? 184 ASN C O   1 
ATOM 4894 C CB  . ASN C 1 184 ? 294.935 259.829 88.573  1.00 63.50  ? 184 ASN C CB  1 
ATOM 4895 C CG  . ASN C 1 184 ? 296.051 259.814 89.589  1.00 63.50  ? 184 ASN C CG  1 
ATOM 4896 O OD1 . ASN C 1 184 ? 296.882 260.721 89.623  1.00 63.50  ? 184 ASN C OD1 1 
ATOM 4897 N ND2 . ASN C 1 184 ? 296.073 258.791 90.432  1.00 63.50  ? 184 ASN C ND2 1 
ATOM 4898 N N   . ASN C 1 185 ? 293.304 262.227 86.316  1.00 66.25  ? 185 ASN C N   1 
ATOM 4899 C CA  . ASN C 1 185 ? 292.259 262.332 85.306  1.00 66.25  ? 185 ASN C CA  1 
ATOM 4900 C C   . ASN C 1 185 ? 292.511 263.601 84.504  1.00 66.25  ? 185 ASN C C   1 
ATOM 4901 O O   . ASN C 1 185 ? 293.561 264.238 84.644  1.00 66.25  ? 185 ASN C O   1 
ATOM 4902 C CB  . ASN C 1 185 ? 290.867 262.321 85.949  1.00 66.25  ? 185 ASN C CB  1 
ATOM 4903 C CG  . ASN C 1 185 ? 290.365 260.924 86.223  1.00 66.25  ? 185 ASN C CG  1 
ATOM 4904 O OD1 . ASN C 1 185 ? 290.369 260.464 87.361  1.00 66.25  ? 185 ASN C OD1 1 
ATOM 4905 N ND2 . ASN C 1 185 ? 289.925 260.242 85.179  1.00 66.25  ? 185 ASN C ND2 1 
ATOM 4906 N N   . LEU C 1 186 ? 291.535 263.949 83.663  1.00 72.45  ? 186 LEU C N   1 
ATOM 4907 C CA  . LEU C 1 186 ? 291.530 265.151 82.820  1.00 72.45  ? 186 LEU C CA  1 
ATOM 4908 C C   . LEU C 1 186 ? 292.754 265.276 81.914  1.00 72.45  ? 186 LEU C C   1 
ATOM 4909 O O   . LEU C 1 186 ? 293.541 266.212 82.049  1.00 72.45  ? 186 LEU C O   1 
ATOM 4910 C CB  . LEU C 1 186 ? 291.399 266.407 83.684  1.00 72.45  ? 186 LEU C CB  1 
ATOM 4911 C CG  . LEU C 1 186 ? 290.128 266.491 84.525  1.00 72.45  ? 186 LEU C CG  1 
ATOM 4912 C CD1 . LEU C 1 186 ? 290.355 267.372 85.731  1.00 72.45  ? 186 LEU C CD1 1 
ATOM 4913 C CD2 . LEU C 1 186 ? 288.981 267.024 83.683  1.00 72.45  ? 186 LEU C CD2 1 
ATOM 4914 N N   . ASP C 1 198 ? 298.525 270.833 88.551  1.00 56.01  ? 198 ASP C N   1 
ATOM 4915 C CA  . ASP C 1 198 ? 297.216 271.461 88.447  1.00 56.01  ? 198 ASP C CA  1 
ATOM 4916 C C   . ASP C 1 198 ? 297.035 272.535 89.509  1.00 56.01  ? 198 ASP C C   1 
ATOM 4917 O O   . ASP C 1 198 ? 297.684 272.510 90.552  1.00 56.01  ? 198 ASP C O   1 
ATOM 4918 C CB  . ASP C 1 198 ? 296.110 270.413 88.560  1.00 56.01  ? 198 ASP C CB  1 
ATOM 4919 C CG  . ASP C 1 198 ? 295.686 269.869 87.212  1.00 56.01  ? 198 ASP C CG  1 
ATOM 4920 O OD1 . ASP C 1 198 ? 295.639 270.656 86.244  1.00 56.01  ? 198 ASP C OD1 1 
ATOM 4921 O OD2 . ASP C 1 198 ? 295.403 268.658 87.117  1.00 56.01  ? 198 ASP C OD2 1 
ATOM 4922 N N   . LEU C 1 199 ? 296.143 273.484 89.227  1.00 53.37  ? 199 LEU C N   1 
ATOM 4923 C CA  . LEU C 1 199 ? 295.912 274.592 90.144  1.00 53.37  ? 199 LEU C CA  1 
ATOM 4924 C C   . LEU C 1 199 ? 294.974 274.210 91.275  1.00 53.37  ? 199 LEU C C   1 
ATOM 4925 O O   . LEU C 1 199 ? 295.018 274.825 92.345  1.00 53.37  ? 199 LEU C O   1 
ATOM 4926 C CB  . LEU C 1 199 ? 295.342 275.797 89.399  1.00 53.37  ? 199 LEU C CB  1 
ATOM 4927 C CG  . LEU C 1 199 ? 296.167 276.390 88.258  1.00 53.37  ? 199 LEU C CG  1 
ATOM 4928 C CD1 . LEU C 1 199 ? 295.709 275.871 86.899  1.00 53.37  ? 199 LEU C CD1 1 
ATOM 4929 C CD2 . LEU C 1 199 ? 296.102 277.904 88.312  1.00 53.37  ? 199 LEU C CD2 1 
ATOM 4930 N N   . VAL C 1 200 ? 294.123 273.209 91.056  1.00 55.47  ? 200 VAL C N   1 
ATOM 4931 C CA  . VAL C 1 200 ? 293.136 272.842 92.063  1.00 55.47  ? 200 VAL C CA  1 
ATOM 4932 C C   . VAL C 1 200 ? 293.797 272.144 93.248  1.00 55.47  ? 200 VAL C C   1 
ATOM 4933 O O   . VAL C 1 200 ? 293.333 272.275 94.389  1.00 55.47  ? 200 VAL C O   1 
ATOM 4934 C CB  . VAL C 1 200 ? 292.029 271.995 91.400  1.00 55.47  ? 200 VAL C CB  1 
ATOM 4935 C CG1 . VAL C 1 200 ? 292.590 270.722 90.828  1.00 55.47  ? 200 VAL C CG1 1 
ATOM 4936 C CG2 . VAL C 1 200 ? 290.887 271.698 92.362  1.00 55.47  ? 200 VAL C CG2 1 
ATOM 4937 N N   . VAL C 1 201 ? 294.921 271.457 93.022  1.00 52.45  ? 201 VAL C N   1 
ATOM 4938 C CA  . VAL C 1 201 ? 295.561 270.713 94.099  1.00 52.45  ? 201 VAL C CA  1 
ATOM 4939 C C   . VAL C 1 201 ? 296.221 271.665 95.085  1.00 52.45  ? 201 VAL C C   1 
ATOM 4940 O O   . VAL C 1 201 ? 296.310 271.366 96.280  1.00 52.45  ? 201 VAL C O   1 
ATOM 4941 C CB  . VAL C 1 201 ? 296.564 269.702 93.518  1.00 52.45  ? 201 VAL C CB  1 
ATOM 4942 C CG1 . VAL C 1 201 ? 296.958 268.668 94.564  1.00 52.45  ? 201 VAL C CG1 1 
ATOM 4943 C CG2 . VAL C 1 201 ? 295.980 269.033 92.287  1.00 52.45  ? 201 VAL C CG2 1 
ATOM 4944 N N   . ASN C 1 202 ? 296.661 272.831 94.622  1.00 50.50  ? 202 ASN C N   1 
ATOM 4945 C CA  . ASN C 1 202 ? 297.117 273.850 95.551  1.00 50.50  ? 202 ASN C CA  1 
ATOM 4946 C C   . ASN C 1 202 ? 295.996 274.764 96.016  1.00 50.50  ? 202 ASN C C   1 
ATOM 4947 O O   . ASN C 1 202 ? 296.127 275.373 97.083  1.00 50.50  ? 202 ASN C O   1 
ATOM 4948 C CB  . ASN C 1 202 ? 298.247 274.684 94.939  1.00 50.50  ? 202 ASN C CB  1 
ATOM 4949 C CG  . ASN C 1 202 ? 297.839 275.387 93.669  1.00 50.50  ? 202 ASN C CG  1 
ATOM 4950 O OD1 . ASN C 1 202 ? 297.156 276.409 93.696  1.00 50.50  ? 202 ASN C OD1 1 
ATOM 4951 N ND2 . ASN C 1 202 ? 298.287 274.858 92.540  1.00 50.50  ? 202 ASN C ND2 1 
ATOM 4952 N N   . TYR C 1 203 ? 294.906 274.871 95.247  1.00 44.64  ? 203 TYR C N   1 
ATOM 4953 C CA  . TYR C 1 203 ? 293.729 275.593 95.723  1.00 44.64  ? 203 TYR C CA  1 
ATOM 4954 C C   . TYR C 1 203 ? 293.138 274.922 96.953  1.00 44.64  ? 203 TYR C C   1 
ATOM 4955 O O   . TYR C 1 203 ? 292.635 275.598 97.857  1.00 44.64  ? 203 TYR C O   1 
ATOM 4956 C CB  . TYR C 1 203 ? 292.673 275.685 94.621  1.00 44.64  ? 203 TYR C CB  1 
ATOM 4957 C CG  . TYR C 1 203 ? 291.342 276.205 95.118  1.00 44.64  ? 203 TYR C CG  1 
ATOM 4958 C CD1 . TYR C 1 203 ? 291.168 277.550 95.382  1.00 44.64  ? 203 TYR C CD1 1 
ATOM 4959 C CD2 . TYR C 1 203 ? 290.266 275.352 95.338  1.00 44.64  ? 203 TYR C CD2 1 
ATOM 4960 C CE1 . TYR C 1 203 ? 289.964 278.036 95.848  1.00 44.64  ? 203 TYR C CE1 1 
ATOM 4961 C CE2 . TYR C 1 203 ? 289.065 275.830 95.812  1.00 44.64  ? 203 TYR C CE2 1 
ATOM 4962 C CZ  . TYR C 1 203 ? 288.919 277.171 96.058  1.00 44.64  ? 203 TYR C CZ  1 
ATOM 4963 O OH  . TYR C 1 203 ? 287.722 277.656 96.523  1.00 44.64  ? 203 TYR C OH  1 
ATOM 4964 N N   . VAL C 1 204 ? 293.168 273.590 96.982  1.00 40.43  ? 204 VAL C N   1 
ATOM 4965 C CA  . VAL C 1 204 ? 292.708 272.838 98.143  1.00 40.43  ? 204 VAL C CA  1 
ATOM 4966 C C   . VAL C 1 204 ? 293.550 273.178 99.363  1.00 40.43  ? 204 VAL C C   1 
ATOM 4967 O O   . VAL C 1 204 ? 293.023 273.417 100.456 1.00 40.43  ? 204 VAL C O   1 
ATOM 4968 C CB  . VAL C 1 204 ? 292.735 271.331 97.832  1.00 40.43  ? 204 VAL C CB  1 
ATOM 4969 C CG1 . VAL C 1 204 ? 292.646 270.503 99.095  1.00 40.43  ? 204 VAL C CG1 1 
ATOM 4970 C CG2 . VAL C 1 204 ? 291.607 270.967 96.897  1.00 40.43  ? 204 VAL C CG2 1 
ATOM 4971 N N   . ASN C 1 205 ? 294.866 273.266 99.183  1.00 38.89  ? 205 ASN C N   1 
ATOM 4972 C CA  . ASN C 1 205 ? 295.752 273.488 100.318 1.00 38.89  ? 205 ASN C CA  1 
ATOM 4973 C C   . ASN C 1 205 ? 295.715 274.931 100.796 1.00 38.89  ? 205 ASN C C   1 
ATOM 4974 O O   . ASN C 1 205 ? 295.895 275.185 101.989 1.00 38.89  ? 205 ASN C O   1 
ATOM 4975 C CB  . ASN C 1 205 ? 297.173 273.080 99.952  1.00 38.89  ? 205 ASN C CB  1 
ATOM 4976 C CG  . ASN C 1 205 ? 297.277 271.615 99.589  1.00 38.89  ? 205 ASN C CG  1 
ATOM 4977 O OD1 . ASN C 1 205 ? 296.541 270.782 100.110 1.00 38.89  ? 205 ASN C OD1 1 
ATOM 4978 N ND2 . ASN C 1 205 ? 298.193 271.294 98.689  1.00 38.89  ? 205 ASN C ND2 1 
ATOM 4979 N N   . THR C 1 206 ? 295.482 275.886 99.896  1.00 41.16  ? 206 THR C N   1 
ATOM 4980 C CA  . THR C 1 206 ? 295.390 277.277 100.328 1.00 41.16  ? 206 THR C CA  1 
ATOM 4981 C C   . THR C 1 206 ? 294.092 277.543 101.075 1.00 41.16  ? 206 THR C C   1 
ATOM 4982 O O   . THR C 1 206 ? 294.093 278.204 102.118 1.00 41.16  ? 206 THR C O   1 
ATOM 4983 C CB  . THR C 1 206 ? 295.503 278.224 99.135  1.00 41.16  ? 206 THR C CB  1 
ATOM 4984 O OG1 . THR C 1 206 ? 294.523 277.877 98.149  1.00 41.16  ? 206 THR C OG1 1 
ATOM 4985 C CG2 . THR C 1 206 ? 296.895 278.184 98.537  1.00 41.16  ? 206 THR C CG2 1 
ATOM 4986 N N   . ASN C 1 207 ? 292.973 277.040 100.560 1.00 36.69  ? 207 ASN C N   1 
ATOM 4987 C CA  . ASN C 1 207 ? 291.670 277.491 101.034 1.00 36.69  ? 207 ASN C CA  1 
ATOM 4988 C C   . ASN C 1 207 ? 291.041 276.520 102.026 1.00 36.69  ? 207 ASN C C   1 
ATOM 4989 O O   . ASN C 1 207 ? 290.745 276.893 103.163 1.00 36.69  ? 207 ASN C O   1 
ATOM 4990 C CB  . ASN C 1 207 ? 290.747 277.724 99.840  1.00 36.69  ? 207 ASN C CB  1 
ATOM 4991 C CG  . ASN C 1 207 ? 291.149 278.933 99.034  1.00 36.69  ? 207 ASN C CG  1 
ATOM 4992 O OD1 . ASN C 1 207 ? 290.540 279.991 99.145  1.00 36.69  ? 207 ASN C OD1 1 
ATOM 4993 N ND2 . ASN C 1 207 ? 292.190 278.790 98.227  1.00 36.69  ? 207 ASN C ND2 1 
ATOM 4994 N N   . MET C 1 208 ? 290.828 275.276 101.609 1.00 32.67  ? 208 MET C N   1 
ATOM 4995 C CA  . MET C 1 208 ? 290.319 274.284 102.544 1.00 32.67  ? 208 MET C CA  1 
ATOM 4996 C C   . MET C 1 208 ? 291.398 273.843 103.513 1.00 32.67  ? 208 MET C C   1 
ATOM 4997 O O   . MET C 1 208 ? 291.092 273.409 104.631 1.00 32.67  ? 208 MET C O   1 
ATOM 4998 C CB  . MET C 1 208 ? 289.767 273.088 101.786 1.00 32.67  ? 208 MET C CB  1 
ATOM 4999 C CG  . MET C 1 208 ? 288.428 273.345 101.170 1.00 32.67  ? 208 MET C CG  1 
ATOM 5000 S SD  . MET C 1 208 ? 288.604 274.243 99.637  1.00 32.67  ? 208 MET C SD  1 
ATOM 5001 C CE  . MET C 1 208 ? 288.658 272.865 98.520  1.00 32.67  ? 208 MET C CE  1 
ATOM 5002 N N   . GLY C 1 209 ? 292.661 273.968 103.104 1.00 22.92  ? 209 GLY C N   1 
ATOM 5003 C CA  . GLY C 1 209 ? 293.762 273.614 103.974 1.00 22.92  ? 209 GLY C CA  1 
ATOM 5004 C C   . GLY C 1 209 ? 293.888 274.514 105.180 1.00 22.92  ? 209 GLY C C   1 
ATOM 5005 O O   . GLY C 1 209 ? 294.218 274.044 106.264 1.00 22.92  ? 209 GLY C O   1 
ATOM 5006 N N   . LEU C 1 210 ? 293.587 275.803 105.027 1.00 14.63  ? 210 LEU C N   1 
ATOM 5007 C CA  . LEU C 1 210 ? 293.692 276.706 106.164 1.00 14.63  ? 210 LEU C CA  1 
ATOM 5008 C C   . LEU C 1 210 ? 292.599 276.439 107.187 1.00 14.63  ? 210 LEU C C   1 
ATOM 5009 O O   . LEU C 1 210 ? 292.871 276.421 108.390 1.00 14.63  ? 210 LEU C O   1 
ATOM 5010 C CB  . LEU C 1 210 ? 293.652 278.154 105.697 1.00 14.63  ? 210 LEU C CB  1 
ATOM 5011 C CG  . LEU C 1 210 ? 293.646 279.208 106.803 1.00 14.63  ? 210 LEU C CG  1 
ATOM 5012 C CD1 . LEU C 1 210 ? 294.843 279.087 107.709 1.00 14.63  ? 210 LEU C CD1 1 
ATOM 5013 C CD2 . LEU C 1 210 ? 293.599 280.580 106.198 1.00 14.63  ? 210 LEU C CD2 1 
ATOM 5014 N N   . LYS C 1 211 ? 291.368 276.204 106.736 1.00 13.59  ? 211 LYS C N   1 
ATOM 5015 C CA  . LYS C 1 211 ? 290.298 275.894 107.676 1.00 13.59  ? 211 LYS C CA  1 
ATOM 5016 C C   . LYS C 1 211 ? 290.496 274.540 108.330 1.00 13.59  ? 211 LYS C C   1 
ATOM 5017 O O   . LYS C 1 211 ? 290.189 274.383 109.516 1.00 13.59  ? 211 LYS C O   1 
ATOM 5018 C CB  . LYS C 1 211 ? 288.947 275.942 106.980 1.00 13.59  ? 211 LYS C CB  1 
ATOM 5019 C CG  . LYS C 1 211 ? 288.682 277.236 106.277 1.00 13.59  ? 211 LYS C CG  1 
ATOM 5020 C CD  . LYS C 1 211 ? 287.765 277.033 105.101 1.00 13.59  ? 211 LYS C CD  1 
ATOM 5021 C CE  . LYS C 1 211 ? 286.332 276.870 105.555 1.00 13.59  ? 211 LYS C CE  1 
ATOM 5022 N NZ  . LYS C 1 211 ? 285.808 278.097 106.205 1.00 13.59  ? 211 LYS C NZ  1 
ATOM 5023 N N   . ILE C 1 212 ? 291.044 273.565 107.600 1.00 10.72  ? 212 ILE C N   1 
ATOM 5024 C CA  . ILE C 1 212 ? 291.318 272.291 108.252 1.00 10.72  ? 212 ILE C CA  1 
ATOM 5025 C C   . ILE C 1 212 ? 292.508 272.414 109.193 1.00 10.72  ? 212 ILE C C   1 
ATOM 5026 O O   . ILE C 1 212 ? 292.559 271.724 110.212 1.00 10.72  ? 212 ILE C O   1 
ATOM 5027 C CB  . ILE C 1 212 ? 291.489 271.158 107.220 1.00 10.72  ? 212 ILE C CB  1 
ATOM 5028 C CG1 . ILE C 1 212 ? 291.163 269.816 107.861 1.00 10.72  ? 212 ILE C CG1 1 
ATOM 5029 C CG2 . ILE C 1 212 ? 292.868 271.102 106.636 1.00 10.72  ? 212 ILE C CG2 1 
ATOM 5030 C CD1 . ILE C 1 212 ? 289.702 269.624 108.125 1.00 10.72  ? 212 ILE C CD1 1 
ATOM 5031 N N   . ARG C 1 213 ? 293.428 273.348 108.933 1.00 10.91  ? 213 ARG C N   1 
ATOM 5032 C CA  . ARG C 1 213 ? 294.544 273.556 109.841 1.00 10.91  ? 213 ARG C CA  1 
ATOM 5033 C C   . ARG C 1 213 ? 294.076 274.184 111.135 1.00 10.91  ? 213 ARG C C   1 
ATOM 5034 O O   . ARG C 1 213 ? 294.489 273.755 112.213 1.00 10.91  ? 213 ARG C O   1 
ATOM 5035 C CB  . ARG C 1 213 ? 295.599 274.427 109.186 1.00 10.91  ? 213 ARG C CB  1 
ATOM 5036 C CG  . ARG C 1 213 ? 296.640 273.651 108.477 1.00 10.91  ? 213 ARG C CG  1 
ATOM 5037 C CD  . ARG C 1 213 ? 297.285 274.494 107.432 1.00 10.91  ? 213 ARG C CD  1 
ATOM 5038 N NE  . ARG C 1 213 ? 297.662 275.780 107.980 1.00 10.91  ? 213 ARG C NE  1 
ATOM 5039 C CZ  . ARG C 1 213 ? 298.197 276.754 107.268 1.00 10.91  ? 213 ARG C CZ  1 
ATOM 5040 N NH1 . ARG C 1 213 ? 298.414 276.583 105.978 1.00 10.91  ? 213 ARG C NH1 1 
ATOM 5041 N NH2 . ARG C 1 213 ? 298.505 277.899 107.842 1.00 10.91  ? 213 ARG C NH2 1 
ATOM 5042 N N   . GLN C 1 214 ? 293.193 275.178 111.044 1.00 11.10  ? 214 GLN C N   1 
ATOM 5043 C CA  . GLN C 1 214 ? 292.641 275.798 112.241 1.00 11.10  ? 214 GLN C CA  1 
ATOM 5044 C C   . GLN C 1 214 ? 291.793 274.821 113.031 1.00 11.10  ? 214 GLN C C   1 
ATOM 5045 O O   . GLN C 1 214 ? 291.845 274.810 114.262 1.00 11.10  ? 214 GLN C O   1 
ATOM 5046 C CB  . GLN C 1 214 ? 291.798 277.004 111.880 1.00 11.10  ? 214 GLN C CB  1 
ATOM 5047 C CG  . GLN C 1 214 ? 292.486 278.073 111.131 1.00 11.10  ? 214 GLN C CG  1 
ATOM 5048 C CD  . GLN C 1 214 ? 291.515 279.120 110.706 1.00 11.10  ? 214 GLN C CD  1 
ATOM 5049 O OE1 . GLN C 1 214 ? 290.494 279.318 111.349 1.00 11.10  ? 214 GLN C OE1 1 
ATOM 5050 N NE2 . GLN C 1 214 ? 291.809 279.794 109.612 1.00 11.10  ? 214 GLN C NE2 1 
ATOM 5051 N N   . LEU C 1 215 ? 291.026 273.978 112.343 1.00 8.68   ? 215 LEU C N   1 
ATOM 5052 C CA  . LEU C 1 215 ? 290.160 273.029 113.035 1.00 8.68   ? 215 LEU C CA  1 
ATOM 5053 C C   . LEU C 1 215 ? 290.973 271.954 113.745 1.00 8.68   ? 215 LEU C C   1 
ATOM 5054 O O   . LEU C 1 215 ? 290.731 271.654 114.924 1.00 8.68   ? 215 LEU C O   1 
ATOM 5055 C CB  . LEU C 1 215 ? 289.189 272.412 112.033 1.00 8.68   ? 215 LEU C CB  1 
ATOM 5056 C CG  . LEU C 1 215 ? 287.933 271.683 112.493 1.00 8.68   ? 215 LEU C CG  1 
ATOM 5057 C CD1 . LEU C 1 215 ? 287.058 272.535 113.328 1.00 8.68   ? 215 LEU C CD1 1 
ATOM 5058 C CD2 . LEU C 1 215 ? 287.173 271.300 111.284 1.00 8.68   ? 215 LEU C CD2 1 
ATOM 5059 N N   . LEU C 1 216 ? 291.963 271.387 113.044 1.00 9.62   ? 216 LEU C N   1 
ATOM 5060 C CA  . LEU C 1 216 ? 292.819 270.370 113.635 1.00 9.62   ? 216 LEU C CA  1 
ATOM 5061 C C   . LEU C 1 216 ? 293.637 270.939 114.776 1.00 9.62   ? 216 LEU C C   1 
ATOM 5062 O O   . LEU C 1 216 ? 293.753 270.301 115.829 1.00 9.62   ? 216 LEU C O   1 
ATOM 5063 C CB  . LEU C 1 216 ? 293.741 269.775 112.580 1.00 9.62   ? 216 LEU C CB  1 
ATOM 5064 C CG  . LEU C 1 216 ? 293.111 268.796 111.607 1.00 9.62   ? 216 LEU C CG  1 
ATOM 5065 C CD1 . LEU C 1 216 ? 294.105 268.384 110.573 1.00 9.62   ? 216 LEU C CD1 1 
ATOM 5066 C CD2 . LEU C 1 216 ? 292.629 267.611 112.347 1.00 9.62   ? 216 LEU C CD2 1 
ATOM 5067 N N   . TRP C 1 217 ? 294.186 272.147 114.594 1.00 8.53   ? 217 TRP C N   1 
ATOM 5068 C CA  . TRP C 1 217 ? 294.956 272.807 115.638 1.00 8.53   ? 217 TRP C CA  1 
ATOM 5069 C C   . TRP C 1 217 ? 294.112 273.039 116.874 1.00 8.53   ? 217 TRP C C   1 
ATOM 5070 O O   . TRP C 1 217 ? 294.554 272.752 117.990 1.00 8.53   ? 217 TRP C O   1 
ATOM 5071 C CB  . TRP C 1 217 ? 295.503 274.137 115.130 1.00 8.53   ? 217 TRP C CB  1 
ATOM 5072 C CG  . TRP C 1 217 ? 296.333 274.828 116.149 1.00 8.53   ? 217 TRP C CG  1 
ATOM 5073 C CD1 . TRP C 1 217 ? 297.661 274.693 116.329 1.00 8.53   ? 217 TRP C CD1 1 
ATOM 5074 C CD2 . TRP C 1 217 ? 295.887 275.758 117.143 1.00 8.53   ? 217 TRP C CD2 1 
ATOM 5075 N NE1 . TRP C 1 217 ? 298.079 275.467 117.372 1.00 8.53   ? 217 TRP C NE1 1 
ATOM 5076 C CE2 . TRP C 1 217 ? 297.002 276.131 117.889 1.00 8.53   ? 217 TRP C CE2 1 
ATOM 5077 C CE3 . TRP C 1 217 ? 294.646 276.305 117.476 1.00 8.53   ? 217 TRP C CE3 1 
ATOM 5078 C CZ2 . TRP C 1 217 ? 296.919 277.018 118.939 1.00 8.53   ? 217 TRP C CZ2 1 
ATOM 5079 C CZ3 . TRP C 1 217 ? 294.568 277.170 118.519 1.00 8.53   ? 217 TRP C CZ3 1 
ATOM 5080 C CH2 . TRP C 1 217 ? 295.691 277.524 119.238 1.00 8.53   ? 217 TRP C CH2 1 
ATOM 5081 N N   . PHE C 1 218 ? 292.891 273.555 116.686 1.00 8.90   ? 218 PHE C N   1 
ATOM 5082 C CA  . PHE C 1 218 ? 292.019 273.867 117.805 1.00 8.90   ? 218 PHE C CA  1 
ATOM 5083 C C   . PHE C 1 218 ? 291.663 272.627 118.592 1.00 8.90   ? 218 PHE C C   1 
ATOM 5084 O O   . PHE C 1 218 ? 291.758 272.627 119.819 1.00 8.90   ? 218 PHE C O   1 
ATOM 5085 C CB  . PHE C 1 218 ? 290.751 274.556 117.309 1.00 8.90   ? 218 PHE C CB  1 
ATOM 5086 C CG  . PHE C 1 218 ? 289.827 274.963 118.410 1.00 8.90   ? 218 PHE C CG  1 
ATOM 5087 C CD1 . PHE C 1 218 ? 290.188 275.946 119.294 1.00 8.90   ? 218 PHE C CD1 1 
ATOM 5088 C CD2 . PHE C 1 218 ? 288.603 274.359 118.561 1.00 8.90   ? 218 PHE C CD2 1 
ATOM 5089 C CE1 . PHE C 1 218 ? 289.351 276.312 120.305 1.00 8.90   ? 218 PHE C CE1 1 
ATOM 5090 C CE2 . PHE C 1 218 ? 287.767 274.721 119.571 1.00 8.90   ? 218 PHE C CE2 1 
ATOM 5091 C CZ  . PHE C 1 218 ? 288.142 275.698 120.443 1.00 8.90   ? 218 PHE C CZ  1 
ATOM 5092 N N   . HIS C 1 219 ? 291.325 271.539 117.910 1.00 8.75   ? 219 HIS C N   1 
ATOM 5093 C CA  . HIS C 1 219 ? 290.853 270.387 118.661 1.00 8.75   ? 219 HIS C CA  1 
ATOM 5094 C C   . HIS C 1 219 ? 291.995 269.599 119.283 1.00 8.75   ? 219 HIS C C   1 
ATOM 5095 O O   . HIS C 1 219 ? 291.857 269.106 120.407 1.00 8.75   ? 219 HIS C O   1 
ATOM 5096 C CB  . HIS C 1 219 ? 289.997 269.513 117.768 1.00 8.75   ? 219 HIS C CB  1 
ATOM 5097 C CG  . HIS C 1 219 ? 288.695 270.142 117.420 1.00 8.75   ? 219 HIS C CG  1 
ATOM 5098 N ND1 . HIS C 1 219 ? 287.770 270.492 118.373 1.00 8.75   ? 219 HIS C ND1 1 
ATOM 5099 C CD2 . HIS C 1 219 ? 288.172 270.508 116.231 1.00 8.75   ? 219 HIS C CD2 1 
ATOM 5100 C CE1 . HIS C 1 219 ? 286.724 271.033 117.784 1.00 8.75   ? 219 HIS C CE1 1 
ATOM 5101 N NE2 . HIS C 1 219 ? 286.942 271.058 116.485 1.00 8.75   ? 219 HIS C NE2 1 
ATOM 5102 N N   . ILE C 1 220 ? 293.142 269.513 118.602 1.00 11.72  ? 220 ILE C N   1 
ATOM 5103 C CA  . ILE C 1 220 ? 294.309 268.854 119.181 1.00 11.72  ? 220 ILE C CA  1 
ATOM 5104 C C   . ILE C 1 220 ? 294.814 269.620 120.397 1.00 11.72  ? 220 ILE C C   1 
ATOM 5105 O O   . ILE C 1 220 ? 295.081 269.028 121.451 1.00 11.72  ? 220 ILE C O   1 
ATOM 5106 C CB  . ILE C 1 220 ? 295.394 268.697 118.105 1.00 11.72  ? 220 ILE C CB  1 
ATOM 5107 C CG1 . ILE C 1 220 ? 295.011 267.592 117.143 1.00 11.72  ? 220 ILE C CG1 1 
ATOM 5108 C CG2 . ILE C 1 220 ? 296.716 268.379 118.713 1.00 11.72  ? 220 ILE C CG2 1 
ATOM 5109 C CD1 . ILE C 1 220 ? 295.748 267.660 115.873 1.00 11.72  ? 220 ILE C CD1 1 
ATOM 5110 N N   . SER C 1 221 ? 294.888 270.951 120.296 1.00 28.56  ? 221 SER C N   1 
ATOM 5111 C CA  . SER C 1 221 ? 295.328 271.763 121.418 1.00 28.56  ? 221 SER C CA  1 
ATOM 5112 C C   . SER C 1 221 ? 294.321 271.776 122.553 1.00 28.56  ? 221 SER C C   1 
ATOM 5113 O O   . SER C 1 221 ? 294.715 271.861 123.716 1.00 28.56  ? 221 SER C O   1 
ATOM 5114 C CB  . SER C 1 221 ? 295.589 273.172 120.936 1.00 28.56  ? 221 SER C CB  1 
ATOM 5115 O OG  . SER C 1 221 ? 296.240 273.110 119.691 1.00 28.56  ? 221 SER C OG  1 
ATOM 5116 N N   . CYS C 1 222 ? 293.029 271.693 122.248 1.00 15.00  ? 222 CYS C N   1 
ATOM 5117 C CA  . CYS C 1 222 ? 292.030 271.647 123.303 1.00 15.00  ? 222 CYS C CA  1 
ATOM 5118 C C   . CYS C 1 222 ? 292.034 270.308 124.008 1.00 15.00  ? 222 CYS C C   1 
ATOM 5119 O O   . CYS C 1 222 ? 291.683 270.229 125.187 1.00 15.00  ? 222 CYS C O   1 
ATOM 5120 C CB  . CYS C 1 222 ? 290.652 271.933 122.727 1.00 15.00  ? 222 CYS C CB  1 
ATOM 5121 S SG  . CYS C 1 222 ? 290.279 273.657 122.504 1.00 15.00  ? 222 CYS C SG  1 
ATOM 5122 N N   . LEU C 1 223 ? 292.417 269.249 123.308 1.00 9.12   ? 223 LEU C N   1 
ATOM 5123 C CA  . LEU C 1 223 ? 292.553 267.961 123.966 1.00 9.12   ? 223 LEU C CA  1 
ATOM 5124 C C   . LEU C 1 223 ? 293.798 267.918 124.835 1.00 9.12   ? 223 LEU C C   1 
ATOM 5125 O O   . LEU C 1 223 ? 293.774 267.360 125.936 1.00 9.12   ? 223 LEU C O   1 
ATOM 5126 C CB  . LEU C 1 223 ? 292.594 266.855 122.923 1.00 9.12   ? 223 LEU C CB  1 
ATOM 5127 C CG  . LEU C 1 223 ? 291.236 266.373 122.457 1.00 9.12   ? 223 LEU C CG  1 
ATOM 5128 C CD1 . LEU C 1 223 ? 291.377 265.584 121.195 1.00 9.12   ? 223 LEU C CD1 1 
ATOM 5129 C CD2 . LEU C 1 223 ? 290.643 265.548 123.542 1.00 9.12   ? 223 LEU C CD2 1 
ATOM 5130 N N   . THR C 1 224 ? 294.888 268.514 124.355 1.00 10.31  ? 224 THR C N   1 
ATOM 5131 C CA  . THR C 1 224 ? 296.152 268.469 125.080 1.00 10.31  ? 224 THR C CA  1 
ATOM 5132 C C   . THR C 1 224 ? 296.129 269.387 126.295 1.00 10.31  ? 224 THR C C   1 
ATOM 5133 O O   . THR C 1 224 ? 296.311 268.938 127.429 1.00 10.31  ? 224 THR C O   1 
ATOM 5134 C CB  . THR C 1 224 ? 297.289 268.857 124.148 1.00 10.31  ? 224 THR C CB  1 
ATOM 5135 O OG1 . THR C 1 224 ? 297.130 268.182 122.905 1.00 10.31  ? 224 THR C OG1 1 
ATOM 5136 C CG2 . THR C 1 224 ? 298.576 268.426 124.730 1.00 10.31  ? 224 THR C CG2 1 
ATOM 5137 N N   . PHE C 1 225 ? 295.896 270.678 126.077 1.00 10.95  ? 225 PHE C N   1 
ATOM 5138 C CA  . PHE C 1 225 ? 296.070 271.686 127.107 1.00 10.95  ? 225 PHE C CA  1 
ATOM 5139 C C   . PHE C 1 225 ? 294.789 272.066 127.823 1.00 10.95  ? 225 PHE C C   1 
ATOM 5140 O O   . PHE C 1 225 ? 294.843 272.851 128.768 1.00 10.95  ? 225 PHE C O   1 
ATOM 5141 C CB  . PHE C 1 225 ? 296.693 272.935 126.496 1.00 10.95  ? 225 PHE C CB  1 
ATOM 5142 C CG  . PHE C 1 225 ? 297.931 272.653 125.721 1.00 10.95  ? 225 PHE C CG  1 
ATOM 5143 C CD1 . PHE C 1 225 ? 299.107 272.387 126.371 1.00 10.95  ? 225 PHE C CD1 1 
ATOM 5144 C CD2 . PHE C 1 225 ? 297.917 272.638 124.348 1.00 10.95  ? 225 PHE C CD2 1 
ATOM 5145 C CE1 . PHE C 1 225 ? 300.237 272.113 125.667 1.00 10.95  ? 225 PHE C CE1 1 
ATOM 5146 C CE2 . PHE C 1 225 ? 299.054 272.362 123.643 1.00 10.95  ? 225 PHE C CE2 1 
ATOM 5147 C CZ  . PHE C 1 225 ? 300.210 272.104 124.305 1.00 10.95  ? 225 PHE C CZ  1 
ATOM 5148 N N   . GLY C 1 226 ? 293.654 271.526 127.426 1.00 10.99  ? 226 GLY C N   1 
ATOM 5149 C CA  . GLY C 1 226 ? 292.395 271.987 127.959 1.00 10.99  ? 226 GLY C CA  1 
ATOM 5150 C C   . GLY C 1 226 ? 291.744 273.004 127.042 1.00 10.99  ? 226 GLY C C   1 
ATOM 5151 O O   . GLY C 1 226 ? 292.371 273.587 126.162 1.00 10.99  ? 226 GLY C O   1 
ATOM 5152 N N   . ARG C 1 227 ? 290.458 273.228 127.259 1.00 20.25  ? 227 ARG C N   1 
ATOM 5153 C CA  . ARG C 1 227 ? 289.706 274.086 126.357 1.00 20.25  ? 227 ARG C CA  1 
ATOM 5154 C C   . ARG C 1 227 ? 289.772 275.545 126.762 1.00 20.25  ? 227 ARG C C   1 
ATOM 5155 O O   . ARG C 1 227 ? 289.899 276.423 125.901 1.00 20.25  ? 227 ARG C O   1 
ATOM 5156 C CB  . ARG C 1 227 ? 288.257 273.628 126.309 1.00 20.25  ? 227 ARG C CB  1 
ATOM 5157 C CG  . ARG C 1 227 ? 287.446 274.252 125.230 1.00 20.25  ? 227 ARG C CG  1 
ATOM 5158 C CD  . ARG C 1 227 ? 286.039 273.761 125.362 1.00 20.25  ? 227 ARG C CD  1 
ATOM 5159 N NE  . ARG C 1 227 ? 285.583 273.819 126.743 1.00 20.25  ? 227 ARG C NE  1 
ATOM 5160 C CZ  . ARG C 1 227 ? 285.101 274.908 127.332 1.00 20.25  ? 227 ARG C CZ  1 
ATOM 5161 N NH1 . ARG C 1 227 ? 285.002 276.045 126.660 1.00 20.25  ? 227 ARG C NH1 1 
ATOM 5162 N NH2 . ARG C 1 227 ? 284.714 274.858 128.599 1.00 20.25  ? 227 ARG C NH2 1 
ATOM 5163 N N   . GLU C 1 228 ? 289.696 275.817 128.062 1.00 20.67  ? 228 GLU C N   1 
ATOM 5164 C CA  . GLU C 1 228 ? 289.809 277.186 128.539 1.00 20.67  ? 228 GLU C CA  1 
ATOM 5165 C C   . GLU C 1 228 ? 291.209 277.735 128.332 1.00 20.67  ? 228 GLU C C   1 
ATOM 5166 O O   . GLU C 1 228 ? 291.367 278.928 128.066 1.00 20.67  ? 228 GLU C O   1 
ATOM 5167 C CB  . GLU C 1 228 ? 289.427 277.267 130.013 1.00 20.67  ? 228 GLU C CB  1 
ATOM 5168 C CG  . GLU C 1 228 ? 287.978 276.903 130.333 1.00 20.67  ? 228 GLU C CG  1 
ATOM 5169 C CD  . GLU C 1 228 ? 287.721 275.406 130.445 1.00 20.67  ? 228 GLU C CD  1 
ATOM 5170 O OE1 . GLU C 1 228 ? 286.565 275.022 130.716 1.00 20.67  ? 228 GLU C OE1 1 
ATOM 5171 O OE2 . GLU C 1 228 ? 288.669 274.611 130.259 1.00 20.67  ? 228 GLU C OE2 1 
ATOM 5172 N N   . THR C 1 229 ? 292.227 276.880 128.422 1.00 11.88  ? 229 THR C N   1 
ATOM 5173 C CA  . THR C 1 229 ? 293.599 277.313 128.192 1.00 11.88  ? 229 THR C CA  1 
ATOM 5174 C C   . THR C 1 229 ? 293.819 277.709 126.741 1.00 11.88  ? 229 THR C C   1 
ATOM 5175 O O   . THR C 1 229 ? 294.516 278.687 126.461 1.00 11.88  ? 229 THR C O   1 
ATOM 5176 C CB  . THR C 1 229 ? 294.558 276.208 128.603 1.00 11.88  ? 229 THR C CB  1 
ATOM 5177 O OG1 . THR C 1 229 ? 294.223 275.764 129.920 1.00 11.88  ? 229 THR C OG1 1 
ATOM 5178 C CG2 . THR C 1 229 ? 295.966 276.709 128.606 1.00 11.88  ? 229 THR C CG2 1 
ATOM 5179 N N   . VAL C 1 230 ? 293.185 277.009 125.805 1.00 9.59   ? 230 VAL C N   1 
ATOM 5180 C CA  . VAL C 1 230 ? 293.290 277.413 124.409 1.00 9.59   ? 230 VAL C CA  1 
ATOM 5181 C C   . VAL C 1 230 ? 292.472 278.671 124.151 1.00 9.59   ? 230 VAL C C   1 
ATOM 5182 O O   . VAL C 1 230 ? 292.904 279.566 123.413 1.00 9.59   ? 230 VAL C O   1 
ATOM 5183 C CB  . VAL C 1 230 ? 292.879 276.252 123.496 1.00 9.59   ? 230 VAL C CB  1 
ATOM 5184 C CG1 . VAL C 1 230 ? 292.877 276.670 122.049 1.00 9.59   ? 230 VAL C CG1 1 
ATOM 5185 C CG2 . VAL C 1 230 ? 293.845 275.144 123.680 1.00 9.59   ? 230 VAL C CG2 1 
ATOM 5186 N N   . LEU C 1 231 ? 291.307 278.791 124.789 1.00 7.19   ? 231 LEU C N   1 
ATOM 5187 C CA  . LEU C 1 231 ? 290.493 279.988 124.604 1.00 7.19   ? 231 LEU C CA  1 
ATOM 5188 C C   . LEU C 1 231 ? 291.125 281.234 125.205 1.00 7.19   ? 231 LEU C C   1 
ATOM 5189 O O   . LEU C 1 231 ? 290.846 282.337 124.733 1.00 7.19   ? 231 LEU C O   1 
ATOM 5190 C CB  . LEU C 1 231 ? 289.109 279.790 125.209 1.00 7.19   ? 231 LEU C CB  1 
ATOM 5191 C CG  . LEU C 1 231 ? 288.162 278.852 124.476 1.00 7.19   ? 231 LEU C CG  1 
ATOM 5192 C CD1 . LEU C 1 231 ? 286.777 279.031 125.023 1.00 7.19   ? 231 LEU C CD1 1 
ATOM 5193 C CD2 . LEU C 1 231 ? 288.192 279.084 122.990 1.00 7.19   ? 231 LEU C CD2 1 
ATOM 5194 N N   . GLU C 1 232 ? 291.959 281.088 126.230 1.00 6.72   ? 232 GLU C N   1 
ATOM 5195 C CA  . GLU C 1 232 ? 292.713 282.227 126.735 1.00 6.72   ? 232 GLU C CA  1 
ATOM 5196 C C   . GLU C 1 232 ? 293.969 282.481 125.924 1.00 6.72   ? 232 GLU C C   1 
ATOM 5197 O O   . GLU C 1 232 ? 294.338 283.643 125.722 1.00 6.72   ? 232 GLU C O   1 
ATOM 5198 C CB  . GLU C 1 232 ? 293.076 282.007 128.195 1.00 6.72   ? 232 GLU C CB  1 
ATOM 5199 C CG  . GLU C 1 232 ? 291.873 281.966 129.095 1.00 6.72   ? 232 GLU C CG  1 
ATOM 5200 C CD  . GLU C 1 232 ? 292.232 281.628 130.515 1.00 6.72   ? 232 GLU C CD  1 
ATOM 5201 O OE1 . GLU C 1 232 ? 293.335 281.093 130.731 1.00 6.72   ? 232 GLU C OE1 1 
ATOM 5202 O OE2 . GLU C 1 232 ? 291.416 281.898 131.418 1.00 6.72   ? 232 GLU C OE2 1 
ATOM 5203 N N   . TYR C 1 233 ? 294.621 281.419 125.442 1.00 5.55   ? 233 TYR C N   1 
ATOM 5204 C CA  . TYR C 1 233 ? 295.810 281.577 124.621 1.00 5.55   ? 233 TYR C CA  1 
ATOM 5205 C C   . TYR C 1 233 ? 295.497 282.264 123.306 1.00 5.55   ? 233 TYR C C   1 
ATOM 5206 O O   . TYR C 1 233 ? 296.351 282.965 122.765 1.00 5.55   ? 233 TYR C O   1 
ATOM 5207 C CB  . TYR C 1 233 ? 296.452 280.214 124.370 1.00 5.55   ? 233 TYR C CB  1 
ATOM 5208 C CG  . TYR C 1 233 ? 297.538 280.221 123.322 1.00 5.55   ? 233 TYR C CG  1 
ATOM 5209 C CD1 . TYR C 1 233 ? 298.803 280.661 123.621 1.00 5.55   ? 233 TYR C CD1 1 
ATOM 5210 C CD2 . TYR C 1 233 ? 297.283 279.800 122.027 1.00 5.55   ? 233 TYR C CD2 1 
ATOM 5211 C CE1 . TYR C 1 233 ? 299.773 280.677 122.674 1.00 5.55   ? 233 TYR C CE1 1 
ATOM 5212 C CE2 . TYR C 1 233 ? 298.243 279.828 121.083 1.00 5.55   ? 233 TYR C CE2 1 
ATOM 5213 C CZ  . TYR C 1 233 ? 299.486 280.255 121.410 1.00 5.55   ? 233 TYR C CZ  1 
ATOM 5214 O OH  . TYR C 1 233 ? 300.454 280.265 120.451 1.00 5.55   ? 233 TYR C OH  1 
ATOM 5215 N N   . LEU C 1 234 ? 294.288 282.086 122.785 1.00 5.23   ? 234 LEU C N   1 
ATOM 5216 C CA  . LEU C 1 234 ? 293.929 282.711 121.519 1.00 5.23   ? 234 LEU C CA  1 
ATOM 5217 C C   . LEU C 1 234 ? 293.883 284.226 121.637 1.00 5.23   ? 234 LEU C C   1 
ATOM 5218 O O   . LEU C 1 234 ? 294.470 284.934 120.812 1.00 5.23   ? 234 LEU C O   1 
ATOM 5219 C CB  . LEU C 1 234 ? 292.587 282.170 121.049 1.00 5.23   ? 234 LEU C CB  1 
ATOM 5220 C CG  . LEU C 1 234 ? 292.551 280.852 120.295 1.00 5.23   ? 234 LEU C CG  1 
ATOM 5221 C CD1 . LEU C 1 234 ? 291.249 280.174 120.554 1.00 5.23   ? 234 LEU C CD1 1 
ATOM 5222 C CD2 . LEU C 1 234 ? 292.682 281.132 118.845 1.00 5.23   ? 234 LEU C CD2 1 
ATOM 5223 N N   . VAL C 1 235 ? 293.242 284.744 122.685 1.00 5.63   ? 235 VAL C N   1 
ATOM 5224 C CA  . VAL C 1 235 ? 293.201 286.190 122.856 1.00 5.63   ? 235 VAL C CA  1 
ATOM 5225 C C   . VAL C 1 235 ? 294.553 286.729 123.321 1.00 5.63   ? 235 VAL C C   1 
ATOM 5226 O O   . VAL C 1 235 ? 294.934 287.840 122.938 1.00 5.63   ? 235 VAL C O   1 
ATOM 5227 C CB  . VAL C 1 235 ? 292.043 286.602 123.788 1.00 5.63   ? 235 VAL C CB  1 
ATOM 5228 C CG1 . VAL C 1 235 ? 290.787 285.869 123.403 1.00 5.63   ? 235 VAL C CG1 1 
ATOM 5229 C CG2 . VAL C 1 235 ? 292.336 286.366 125.248 1.00 5.63   ? 235 VAL C CG2 1 
ATOM 5230 N N   . SER C 1 236 ? 295.337 285.932 124.060 1.00 5.64   ? 236 SER C N   1 
ATOM 5231 C CA  . SER C 1 236 ? 296.653 286.384 124.493 1.00 5.64   ? 236 SER C CA  1 
ATOM 5232 C C   . SER C 1 236 ? 297.615 286.499 123.322 1.00 5.64   ? 236 SER C C   1 
ATOM 5233 O O   . SER C 1 236 ? 298.297 287.516 123.175 1.00 5.64   ? 236 SER C O   1 
ATOM 5234 C CB  . SER C 1 236 ? 297.203 285.438 125.545 1.00 5.64   ? 236 SER C CB  1 
ATOM 5235 O OG  . SER C 1 236 ? 296.353 285.420 126.666 1.00 5.64   ? 236 SER C OG  1 
ATOM 5236 N N   . PHE C 1 237 ? 297.662 285.485 122.458 1.00 10.26  ? 237 PHE C N   1 
ATOM 5237 C CA  . PHE C 1 237 ? 298.519 285.570 121.289 1.00 10.26  ? 237 PHE C CA  1 
ATOM 5238 C C   . PHE C 1 237 ? 298.011 286.592 120.290 1.00 10.26  ? 237 PHE C C   1 
ATOM 5239 O O   . PHE C 1 237 ? 298.821 287.215 119.594 1.00 10.26  ? 237 PHE C O   1 
ATOM 5240 C CB  . PHE C 1 237 ? 298.656 284.215 120.608 1.00 10.26  ? 237 PHE C CB  1 
ATOM 5241 C CG  . PHE C 1 237 ? 299.727 284.182 119.557 1.00 10.26  ? 237 PHE C CG  1 
ATOM 5242 C CD1 . PHE C 1 237 ? 301.032 283.980 119.907 1.00 10.26  ? 237 PHE C CD1 1 
ATOM 5243 C CD2 . PHE C 1 237 ? 299.427 284.366 118.224 1.00 10.26  ? 237 PHE C CD2 1 
ATOM 5244 C CE1 . PHE C 1 237 ? 302.010 283.964 118.965 1.00 10.26  ? 237 PHE C CE1 1 
ATOM 5245 C CE2 . PHE C 1 237 ? 300.405 284.355 117.281 1.00 10.26  ? 237 PHE C CE2 1 
ATOM 5246 C CZ  . PHE C 1 237 ? 301.696 284.150 117.651 1.00 10.26  ? 237 PHE C CZ  1 
ATOM 5247 N N   . GLY C 1 238 ? 296.695 286.794 120.208 1.00 10.55  ? 238 GLY C N   1 
ATOM 5248 C CA  . GLY C 1 238 ? 296.179 287.814 119.314 1.00 10.55  ? 238 GLY C CA  1 
ATOM 5249 C C   . GLY C 1 238 ? 296.625 289.206 119.708 1.00 10.55  ? 238 GLY C C   1 
ATOM 5250 O O   . GLY C 1 238 ? 297.276 289.901 118.926 1.00 10.55  ? 238 GLY C O   1 
ATOM 5251 N N   . VAL C 1 239 ? 296.359 289.599 120.959 1.00 11.68  ? 239 VAL C N   1 
ATOM 5252 C CA  . VAL C 1 239 ? 296.795 290.920 121.390 1.00 11.68  ? 239 VAL C CA  1 
ATOM 5253 C C   . VAL C 1 239 ? 298.306 291.013 121.520 1.00 11.68  ? 239 VAL C C   1 
ATOM 5254 O O   . VAL C 1 239 ? 298.838 292.120 121.485 1.00 11.68  ? 239 VAL C O   1 
ATOM 5255 C CB  . VAL C 1 239 ? 296.125 291.352 122.706 1.00 11.68  ? 239 VAL C CB  1 
ATOM 5256 C CG1 . VAL C 1 239 ? 294.663 291.060 122.666 1.00 11.68  ? 239 VAL C CG1 1 
ATOM 5257 C CG2 . VAL C 1 239 ? 296.761 290.712 123.899 1.00 11.68  ? 239 VAL C CG2 1 
ATOM 5258 N N   . TRP C 1 240 ? 299.025 289.888 121.638 1.00 28.56  ? 240 TRP C N   1 
ATOM 5259 C CA  . TRP C 1 240 ? 300.477 289.954 121.604 1.00 28.56  ? 240 TRP C CA  1 
ATOM 5260 C C   . TRP C 1 240 ? 300.967 290.292 120.216 1.00 28.56  ? 240 TRP C C   1 
ATOM 5261 O O   . TRP C 1 240 ? 301.936 291.033 120.064 1.00 28.56  ? 240 TRP C O   1 
ATOM 5262 C CB  . TRP C 1 240 ? 301.088 288.637 122.066 1.00 28.56  ? 240 TRP C CB  1 
ATOM 5263 C CG  . TRP C 1 240 ? 302.574 288.691 122.190 1.00 28.56  ? 240 TRP C CG  1 
ATOM 5264 C CD1 . TRP C 1 240 ? 303.283 289.026 123.293 1.00 28.56  ? 240 TRP C CD1 1 
ATOM 5265 C CD2 . TRP C 1 240 ? 303.534 288.401 121.172 1.00 28.56  ? 240 TRP C CD2 1 
ATOM 5266 N NE1 . TRP C 1 240 ? 304.619 288.970 123.031 1.00 28.56  ? 240 TRP C NE1 1 
ATOM 5267 C CE2 . TRP C 1 240 ? 304.798 288.593 121.730 1.00 28.56  ? 240 TRP C CE2 1 
ATOM 5268 C CE3 . TRP C 1 240 ? 303.443 287.996 119.841 1.00 28.56  ? 240 TRP C CE3 1 
ATOM 5269 C CZ2 . TRP C 1 240 ? 305.957 288.403 121.008 1.00 28.56  ? 240 TRP C CZ2 1 
ATOM 5270 C CZ3 . TRP C 1 240 ? 304.593 287.806 119.131 1.00 28.56  ? 240 TRP C CZ3 1 
ATOM 5271 C CH2 . TRP C 1 240 ? 305.830 288.006 119.710 1.00 28.56  ? 240 TRP C CH2 1 
ATOM 5272 N N   . ILE C 1 241 ? 300.329 289.752 119.185 1.00 16.02  ? 241 ILE C N   1 
ATOM 5273 C CA  . ILE C 1 241 ? 300.814 290.061 117.852 1.00 16.02  ? 241 ILE C CA  1 
ATOM 5274 C C   . ILE C 1 241 ? 300.329 291.433 117.401 1.00 16.02  ? 241 ILE C C   1 
ATOM 5275 O O   . ILE C 1 241 ? 300.886 291.995 116.454 1.00 16.02  ? 241 ILE C O   1 
ATOM 5276 C CB  . ILE C 1 241 ? 300.432 288.936 116.873 1.00 16.02  ? 241 ILE C CB  1 
ATOM 5277 C CG1 . ILE C 1 241 ? 301.380 288.904 115.686 1.00 16.02  ? 241 ILE C CG1 1 
ATOM 5278 C CG2 . ILE C 1 241 ? 299.060 289.126 116.321 1.00 16.02  ? 241 ILE C CG2 1 
ATOM 5279 C CD1 . ILE C 1 241 ? 302.764 288.550 116.059 1.00 16.02  ? 241 ILE C CD1 1 
ATOM 5280 N N   . ARG C 1 242 ? 299.331 292.021 118.075 1.00 11.38  ? 242 ARG C N   1 
ATOM 5281 C CA  . ARG C 1 242 ? 298.912 293.361 117.666 1.00 11.38  ? 242 ARG C CA  1 
ATOM 5282 C C   . ARG C 1 242 ? 299.809 294.467 118.209 1.00 11.38  ? 242 ARG C C   1 
ATOM 5283 O O   . ARG C 1 242 ? 299.994 295.475 117.520 1.00 11.38  ? 242 ARG C O   1 
ATOM 5284 C CB  . ARG C 1 242 ? 297.486 293.660 118.107 1.00 11.38  ? 242 ARG C CB  1 
ATOM 5285 C CG  . ARG C 1 242 ? 296.463 292.665 117.676 1.00 11.38  ? 242 ARG C CG  1 
ATOM 5286 C CD  . ARG C 1 242 ? 296.249 292.585 116.212 1.00 11.38  ? 242 ARG C CD  1 
ATOM 5287 N NE  . ARG C 1 242 ? 295.509 291.377 115.891 1.00 11.38  ? 242 ARG C NE  1 
ATOM 5288 C CZ  . ARG C 1 242 ? 295.034 291.102 114.689 1.00 11.38  ? 242 ARG C CZ  1 
ATOM 5289 N NH1 . ARG C 1 242 ? 295.187 291.969 113.706 1.00 11.38  ? 242 ARG C NH1 1 
ATOM 5290 N NH2 . ARG C 1 242 ? 294.394 289.972 114.474 1.00 11.38  ? 242 ARG C NH2 1 
ATOM 5291 N N   . THR C 1 243 ? 300.344 294.319 119.427 1.00 9.49   ? 243 THR C N   1 
ATOM 5292 C CA  . THR C 1 243 ? 301.077 295.393 120.093 1.00 9.49   ? 243 THR C CA  1 
ATOM 5293 C C   . THR C 1 243 ? 302.360 295.730 119.340 1.00 9.49   ? 243 THR C C   1 
ATOM 5294 O O   . THR C 1 243 ? 302.881 294.898 118.597 1.00 9.49   ? 243 THR C O   1 
ATOM 5295 C CB  . THR C 1 243 ? 301.438 295.009 121.523 1.00 9.49   ? 243 THR C CB  1 
ATOM 5296 O OG1 . THR C 1 243 ? 302.091 293.751 121.518 1.00 9.49   ? 243 THR C OG1 1 
ATOM 5297 C CG2 . THR C 1 243 ? 300.232 294.920 122.391 1.00 9.49   ? 243 THR C CG2 1 
ATOM 5298 N N   . PRO C 1 244 ? 302.858 296.963 119.464 1.00 12.68  ? 244 PRO C N   1 
ATOM 5299 C CA  . PRO C 1 244 ? 304.179 297.262 118.936 1.00 12.68  ? 244 PRO C CA  1 
ATOM 5300 C C   . PRO C 1 244 ? 305.234 296.493 119.706 1.00 12.68  ? 244 PRO C C   1 
ATOM 5301 O O   . PRO C 1 244 ? 305.054 296.196 120.898 1.00 12.68  ? 244 PRO C O   1 
ATOM 5302 C CB  . PRO C 1 244 ? 304.309 298.779 119.154 1.00 12.68  ? 244 PRO C CB  1 
ATOM 5303 C CG  . PRO C 1 244 ? 302.938 299.248 119.147 1.00 12.68  ? 244 PRO C CG  1 
ATOM 5304 C CD  . PRO C 1 244 ? 302.166 298.197 119.861 1.00 12.68  ? 244 PRO C CD  1 
ATOM 5305 N N   . PRO C 1 245 ? 306.347 296.126 119.060 1.00 28.56  ? 245 PRO C N   1 
ATOM 5306 C CA  . PRO C 1 245 ? 307.284 295.180 119.682 1.00 28.56  ? 245 PRO C CA  1 
ATOM 5307 C C   . PRO C 1 245 ? 307.987 295.723 120.905 1.00 28.56  ? 245 PRO C C   1 
ATOM 5308 O O   . PRO C 1 245 ? 308.403 294.941 121.766 1.00 28.56  ? 245 PRO C O   1 
ATOM 5309 C CB  . PRO C 1 245 ? 308.288 294.895 118.558 1.00 28.56  ? 245 PRO C CB  1 
ATOM 5310 C CG  . PRO C 1 245 ? 307.659 295.387 117.324 1.00 28.56  ? 245 PRO C CG  1 
ATOM 5311 C CD  . PRO C 1 245 ? 306.770 296.498 117.704 1.00 28.56  ? 245 PRO C CD  1 
ATOM 5312 N N   . ALA C 1 246 ? 308.109 297.038 121.019 1.00 13.81  ? 246 ALA C N   1 
ATOM 5313 C CA  . ALA C 1 246 ? 308.849 297.652 122.103 1.00 13.81  ? 246 ALA C CA  1 
ATOM 5314 C C   . ALA C 1 246 ? 308.087 297.677 123.413 1.00 13.81  ? 246 ALA C C   1 
ATOM 5315 O O   . ALA C 1 246 ? 308.659 298.082 124.426 1.00 13.81  ? 246 ALA C O   1 
ATOM 5316 C CB  . ALA C 1 246 ? 309.235 299.069 121.708 1.00 13.81  ? 246 ALA C CB  1 
ATOM 5317 N N   . TYR C 1 247 ? 306.823 297.248 123.427 1.00 13.78  ? 247 TYR C N   1 
ATOM 5318 C CA  . TYR C 1 247 ? 305.973 297.363 124.606 1.00 13.78  ? 247 TYR C CA  1 
ATOM 5319 C C   . TYR C 1 247 ? 305.222 296.074 124.904 1.00 13.78  ? 247 TYR C C   1 
ATOM 5320 O O   . TYR C 1 247 ? 304.181 296.114 125.557 1.00 13.78  ? 247 TYR C O   1 
ATOM 5321 C CB  . TYR C 1 247 ? 304.982 298.518 124.450 1.00 13.78  ? 247 TYR C CB  1 
ATOM 5322 C CG  . TYR C 1 247 ? 305.618 299.828 124.042 1.00 13.78  ? 247 TYR C CG  1 
ATOM 5323 C CD1 . TYR C 1 247 ? 306.155 300.674 124.987 1.00 13.78  ? 247 TYR C CD1 1 
ATOM 5324 C CD2 . TYR C 1 247 ? 305.677 300.211 122.713 1.00 13.78  ? 247 TYR C CD2 1 
ATOM 5325 C CE1 . TYR C 1 247 ? 306.738 301.855 124.623 1.00 13.78  ? 247 TYR C CE1 1 
ATOM 5326 C CE2 . TYR C 1 247 ? 306.262 301.389 122.341 1.00 13.78  ? 247 TYR C CE2 1 
ATOM 5327 C CZ  . TYR C 1 247 ? 306.787 302.206 123.300 1.00 13.78  ? 247 TYR C CZ  1 
ATOM 5328 O OH  . TYR C 1 247 ? 307.372 303.386 122.929 1.00 13.78  ? 247 TYR C OH  1 
ATOM 5329 N N   . ARG C 1 248 ? 305.725 294.938 124.441 1.00 18.07  ? 248 ARG C N   1 
ATOM 5330 C CA  . ARG C 1 248 ? 305.180 293.623 124.746 1.00 18.07  ? 248 ARG C CA  1 
ATOM 5331 C C   . ARG C 1 248 ? 306.299 292.768 125.318 1.00 18.07  ? 248 ARG C C   1 
ATOM 5332 O O   . ARG C 1 248 ? 307.461 293.189 125.271 1.00 18.07  ? 248 ARG C O   1 
ATOM 5333 C CB  . ARG C 1 248 ? 304.601 292.977 123.494 1.00 18.07  ? 248 ARG C CB  1 
ATOM 5334 C CG  . ARG C 1 248 ? 305.598 292.822 122.392 1.00 18.07  ? 248 ARG C CG  1 
ATOM 5335 C CD  . ARG C 1 248 ? 304.978 292.100 121.234 1.00 18.07  ? 248 ARG C CD  1 
ATOM 5336 N NE  . ARG C 1 248 ? 305.953 291.844 120.193 1.00 18.07  ? 248 ARG C NE  1 
ATOM 5337 C CZ  . ARG C 1 248 ? 305.655 291.767 118.908 1.00 18.07  ? 248 ARG C CZ  1 
ATOM 5338 N NH1 . ARG C 1 248 ? 306.604 291.532 118.023 1.00 18.07  ? 248 ARG C NH1 1 
ATOM 5339 N NH2 . ARG C 1 248 ? 304.408 291.917 118.512 1.00 18.07  ? 248 ARG C NH2 1 
ATOM 5340 N N   . PRO C 1 249 ? 306.004 291.606 125.900 1.00 16.96  ? 249 PRO C N   1 
ATOM 5341 C CA  . PRO C 1 249 ? 307.062 290.647 126.180 1.00 16.96  ? 249 PRO C CA  1 
ATOM 5342 C C   . PRO C 1 249 ? 307.757 290.228 124.899 1.00 16.96  ? 249 PRO C C   1 
ATOM 5343 O O   . PRO C 1 249 ? 307.131 290.169 123.828 1.00 16.96  ? 249 PRO C O   1 
ATOM 5344 C CB  . PRO C 1 249 ? 306.309 289.477 126.822 1.00 16.96  ? 249 PRO C CB  1 
ATOM 5345 C CG  . PRO C 1 249 ? 305.193 290.105 127.495 1.00 16.96  ? 249 PRO C CG  1 
ATOM 5346 C CD  . PRO C 1 249 ? 304.791 291.291 126.674 1.00 16.96  ? 249 PRO C CD  1 
ATOM 5347 N N   . PRO C 1 250 ? 309.058 289.944 124.960 1.00 15.18  ? 250 PRO C N   1 
ATOM 5348 C CA  . PRO C 1 250 ? 309.833 289.843 123.719 1.00 15.18  ? 250 PRO C CA  1 
ATOM 5349 C C   . PRO C 1 250 ? 309.681 288.527 122.992 1.00 15.18  ? 250 PRO C C   1 
ATOM 5350 O O   . PRO C 1 250 ? 309.914 288.483 121.777 1.00 15.18  ? 250 PRO C O   1 
ATOM 5351 C CB  . PRO C 1 250 ? 311.270 290.031 124.199 1.00 15.18  ? 250 PRO C CB  1 
ATOM 5352 C CG  . PRO C 1 250 ? 311.257 289.494 125.566 1.00 15.18  ? 250 PRO C CG  1 
ATOM 5353 C CD  . PRO C 1 250 ? 309.894 289.699 126.145 1.00 15.18  ? 250 PRO C CD  1 
ATOM 5354 N N   . ASN C 1 251 ? 309.290 287.465 123.681 1.00 16.12  ? 251 ASN C N   1 
ATOM 5355 C CA  . ASN C 1 251 ? 309.190 286.145 123.091 1.00 16.12  ? 251 ASN C CA  1 
ATOM 5356 C C   . ASN C 1 251 ? 307.729 285.749 122.972 1.00 16.12  ? 251 ASN C C   1 
ATOM 5357 O O   . ASN C 1 251 ? 306.932 286.008 123.878 1.00 16.12  ? 251 ASN C O   1 
ATOM 5358 C CB  . ASN C 1 251 ? 309.969 285.135 123.922 1.00 16.12  ? 251 ASN C CB  1 
ATOM 5359 C CG  . ASN C 1 251 ? 309.775 285.326 125.403 1.00 16.12  ? 251 ASN C CG  1 
ATOM 5360 O OD1 . ASN C 1 251 ? 308.986 286.157 125.839 1.00 16.12  ? 251 ASN C OD1 1 
ATOM 5361 N ND2 . ASN C 1 251 ? 310.511 284.559 126.192 1.00 16.12  ? 251 ASN C ND2 1 
ATOM 5362 N N   . ALA C 1 252 ? 307.395 285.130 121.839 1.00 14.07  ? 252 ALA C N   1 
ATOM 5363 C CA  . ALA C 1 252 ? 306.017 284.830 121.492 1.00 14.07  ? 252 ALA C CA  1 
ATOM 5364 C C   . ALA C 1 252 ? 305.432 283.830 122.476 1.00 14.07  ? 252 ALA C C   1 
ATOM 5365 O O   . ALA C 1 252 ? 306.165 283.021 123.043 1.00 14.07  ? 252 ALA C O   1 
ATOM 5366 C CB  . ALA C 1 252 ? 305.941 284.277 120.077 1.00 14.07  ? 252 ALA C CB  1 
ATOM 5367 N N   . PRO C 1 253 ? 304.135 283.907 122.751 1.00 10.05  ? 253 PRO C N   1 
ATOM 5368 C CA  . PRO C 1 253 ? 303.527 282.928 123.651 1.00 10.05  ? 253 PRO C CA  1 
ATOM 5369 C C   . PRO C 1 253 ? 303.524 281.539 123.040 1.00 10.05  ? 253 PRO C C   1 
ATOM 5370 O O   . PRO C 1 253 ? 303.314 281.359 121.840 1.00 10.05  ? 253 PRO C O   1 
ATOM 5371 C CB  . PRO C 1 253 ? 302.107 283.461 123.846 1.00 10.05  ? 253 PRO C CB  1 
ATOM 5372 C CG  . PRO C 1 253 ? 302.211 284.878 123.569 1.00 10.05  ? 253 PRO C CG  1 
ATOM 5373 C CD  . PRO C 1 253 ? 303.223 285.026 122.494 1.00 10.05  ? 253 PRO C CD  1 
ATOM 5374 N N   . ILE C 1 254 ? 303.808 280.557 123.879 1.00 8.46   ? 254 ILE C N   1 
ATOM 5375 C CA  . ILE C 1 254 ? 303.714 279.160 123.509 1.00 8.46   ? 254 ILE C CA  1 
ATOM 5376 C C   . ILE C 1 254 ? 302.854 278.532 124.586 1.00 8.46   ? 254 ILE C C   1 
ATOM 5377 O O   . ILE C 1 254 ? 302.661 279.094 125.665 1.00 8.46   ? 254 ILE C O   1 
ATOM 5378 C CB  . ILE C 1 254 ? 305.101 278.482 123.401 1.00 8.46   ? 254 ILE C CB  1 
ATOM 5379 C CG1 . ILE C 1 254 ? 305.078 277.295 122.444 1.00 8.46   ? 254 ILE C CG1 1 
ATOM 5380 C CG2 . ILE C 1 254 ? 305.604 278.026 124.750 1.00 8.46   ? 254 ILE C CG2 1 
ATOM 5381 C CD1 . ILE C 1 254 ? 304.932 277.688 121.009 1.00 8.46   ? 254 ILE C CD1 1 
ATOM 5382 N N   . LEU C 1 255 ? 302.278 277.393 124.268 1.00 7.63   ? 255 LEU C N   1 
ATOM 5383 C CA  . LEU C 1 255 ? 301.475 276.659 125.228 1.00 7.63   ? 255 LEU C CA  1 
ATOM 5384 C C   . LEU C 1 255 ? 302.082 275.270 125.339 1.00 7.63   ? 255 LEU C C   1 
ATOM 5385 O O   . LEU C 1 255 ? 302.300 274.601 124.325 1.00 7.63   ? 255 LEU C O   1 
ATOM 5386 C CB  . LEU C 1 255 ? 299.998 276.666 124.819 1.00 7.63   ? 255 LEU C CB  1 
ATOM 5387 C CG  . LEU C 1 255 ? 299.323 275.955 123.649 1.00 7.63   ? 255 LEU C CG  1 
ATOM 5388 C CD1 . LEU C 1 255 ? 297.857 276.239 123.768 1.00 7.63   ? 255 LEU C CD1 1 
ATOM 5389 C CD2 . LEU C 1 255 ? 299.824 276.355 122.277 1.00 7.63   ? 255 LEU C CD2 1 
ATOM 5390 N N   . SER C 1 256 ? 302.433 274.876 126.558 1.00 9.01   ? 256 SER C N   1 
ATOM 5391 C CA  . SER C 1 256 ? 303.268 273.703 126.768 1.00 9.01   ? 256 SER C CA  1 
ATOM 5392 C C   . SER C 1 256 ? 303.055 273.212 128.189 1.00 9.01   ? 256 SER C C   1 
ATOM 5393 O O   . SER C 1 256 ? 302.289 273.795 128.955 1.00 9.01   ? 256 SER C O   1 
ATOM 5394 C CB  . SER C 1 256 ? 304.735 274.024 126.506 1.00 9.01   ? 256 SER C CB  1 
ATOM 5395 O OG  . SER C 1 256 ? 305.278 274.767 127.576 1.00 9.01   ? 256 SER C OG  1 
ATOM 5396 N N   . THR C 1 257 ? 303.720 272.113 128.527 1.00 17.24  ? 257 THR C N   1 
ATOM 5397 C CA  . THR C 1 257 ? 303.783 271.636 129.911 1.00 17.24  ? 257 THR C CA  1 
ATOM 5398 C C   . THR C 1 257 ? 305.210 271.230 130.304 1.00 17.24  ? 257 THR C C   1 
ATOM 5399 O O   . THR C 1 257 ? 305.956 270.652 129.519 1.00 17.24  ? 257 THR C O   1 
ATOM 5400 C CB  . THR C 1 257 ? 302.823 270.445 130.167 1.00 17.24  ? 257 THR C CB  1 
ATOM 5401 O OG1 . THR C 1 257 ? 302.922 269.489 129.105 1.00 17.24  ? 257 THR C OG1 1 
ATOM 5402 C CG2 . THR C 1 257 ? 301.394 270.915 130.304 1.00 17.24  ? 257 THR C CG2 1 
ATOM 5403 N N   . ASN D 1 14  ? 316.631 275.103 84.970  1.00 80.47  ? 14  ASN D N   1 
ATOM 5404 C CA  . ASN D 1 14  ? 315.564 275.495 84.058  1.00 80.47  ? 14  ASN D CA  1 
ATOM 5405 C C   . ASN D 1 14  ? 314.424 274.483 84.088  1.00 80.47  ? 14  ASN D C   1 
ATOM 5406 O O   . ASN D 1 14  ? 314.618 273.324 84.452  1.00 80.47  ? 14  ASN D O   1 
ATOM 5407 C CB  . ASN D 1 14  ? 316.105 275.642 82.636  1.00 80.47  ? 14  ASN D CB  1 
ATOM 5408 C CG  . ASN D 1 14  ? 315.444 276.771 81.873  1.00 80.47  ? 14  ASN D CG  1 
ATOM 5409 O OD1 . ASN D 1 14  ? 314.220 276.833 81.769  1.00 80.47  ? 14  ASN D OD1 1 
ATOM 5410 N ND2 . ASN D 1 14  ? 316.254 277.672 81.333  1.00 80.47  ? 14  ASN D ND2 1 
ATOM 5411 N N   . GLU D 1 15  ? 313.229 274.935 83.707  1.00 87.00  ? 15  GLU D N   1 
ATOM 5412 C CA  . GLU D 1 15  ? 312.065 274.056 83.700  1.00 87.00  ? 15  GLU D CA  1 
ATOM 5413 C C   . GLU D 1 15  ? 312.091 273.070 82.540  1.00 87.00  ? 15  GLU D C   1 
ATOM 5414 O O   . GLU D 1 15  ? 311.667 271.920 82.701  1.00 87.00  ? 15  GLU D O   1 
ATOM 5415 C CB  . GLU D 1 15  ? 310.782 274.886 83.648  1.00 87.00  ? 15  GLU D CB  1 
ATOM 5416 C CG  . GLU D 1 15  ? 310.076 275.046 84.983  1.00 87.00  ? 15  GLU D CG  1 
ATOM 5417 C CD  . GLU D 1 15  ? 309.765 273.721 85.646  1.00 87.00  ? 15  GLU D CD  1 
ATOM 5418 O OE1 . GLU D 1 15  ? 309.198 272.830 84.972  1.00 87.00  ? 15  GLU D OE1 1 
ATOM 5419 O OE2 . GLU D 1 15  ? 310.077 273.572 86.844  1.00 87.00  ? 15  GLU D OE2 1 
ATOM 5420 N N   . ASN D 1 16  ? 312.576 273.494 81.375  1.00 83.74  ? 16  ASN D N   1 
ATOM 5421 C CA  . ASN D 1 16  ? 312.595 272.642 80.194  1.00 83.74  ? 16  ASN D CA  1 
ATOM 5422 C C   . ASN D 1 16  ? 313.871 271.818 80.074  1.00 83.74  ? 16  ASN D C   1 
ATOM 5423 O O   . ASN D 1 16  ? 313.853 270.766 79.423  1.00 83.74  ? 16  ASN D O   1 
ATOM 5424 C CB  . ASN D 1 16  ? 312.414 273.500 78.935  1.00 83.74  ? 16  ASN D CB  1 
ATOM 5425 C CG  . ASN D 1 16  ? 312.160 272.672 77.691  1.00 83.74  ? 16  ASN D CG  1 
ATOM 5426 O OD1 . ASN D 1 16  ? 312.895 272.767 76.709  1.00 83.74  ? 16  ASN D OD1 1 
ATOM 5427 N ND2 . ASN D 1 16  ? 311.114 271.854 77.727  1.00 83.74  ? 16  ASN D ND2 1 
ATOM 5428 N N   . SER D 1 17  ? 314.964 272.261 80.694  1.00 78.65  ? 17  SER D N   1 
ATOM 5429 C CA  . SER D 1 17  ? 316.258 271.611 80.536  1.00 78.65  ? 17  SER D CA  1 
ATOM 5430 C C   . SER D 1 17  ? 316.288 270.252 81.235  1.00 78.65  ? 17  SER D C   1 
ATOM 5431 O O   . SER D 1 17  ? 315.479 269.952 82.117  1.00 78.65  ? 17  SER D O   1 
ATOM 5432 C CB  . SER D 1 17  ? 317.373 272.500 81.085  1.00 78.65  ? 17  SER D CB  1 
ATOM 5433 O OG  . SER D 1 17  ? 317.363 272.500 82.500  1.00 78.65  ? 17  SER D OG  1 
ATOM 5434 N N   . LEU D 1 18  ? 317.248 269.425 80.821  1.00 74.94  ? 18  LEU D N   1 
ATOM 5435 C CA  . LEU D 1 18  ? 317.360 268.057 81.309  1.00 74.94  ? 18  LEU D CA  1 
ATOM 5436 C C   . LEU D 1 18  ? 318.085 267.962 82.647  1.00 74.94  ? 18  LEU D C   1 
ATOM 5437 O O   . LEU D 1 18  ? 318.192 266.859 83.196  1.00 74.94  ? 18  LEU D O   1 
ATOM 5438 C CB  . LEU D 1 18  ? 318.080 267.196 80.261  1.00 74.94  ? 18  LEU D CB  1 
ATOM 5439 C CG  . LEU D 1 18  ? 317.816 265.687 80.159  1.00 74.94  ? 18  LEU D CG  1 
ATOM 5440 C CD1 . LEU D 1 18  ? 316.328 265.382 80.207  1.00 74.94  ? 18  LEU D CD1 1 
ATOM 5441 C CD2 . LEU D 1 18  ? 318.444 265.108 78.899  1.00 74.94  ? 18  LEU D CD2 1 
ATOM 5442 N N   . GLU D 1 19  ? 318.578 269.081 83.191  1.00 82.91  ? 19  GLU D N   1 
ATOM 5443 C CA  . GLU D 1 19  ? 319.354 269.011 84.426  1.00 82.91  ? 19  GLU D CA  1 
ATOM 5444 C C   . GLU D 1 19  ? 318.465 268.754 85.637  1.00 82.91  ? 19  GLU D C   1 
ATOM 5445 O O   . GLU D 1 19  ? 318.889 268.066 86.569  1.00 82.91  ? 19  GLU D O   1 
ATOM 5446 C CB  . GLU D 1 19  ? 320.207 270.280 84.589  1.00 82.91  ? 19  GLU D CB  1 
ATOM 5447 C CG  . GLU D 1 19  ? 319.490 271.603 84.878  1.00 82.91  ? 19  GLU D CG  1 
ATOM 5448 C CD  . GLU D 1 19  ? 319.228 271.849 86.354  1.00 82.91  ? 19  GLU D CD  1 
ATOM 5449 O OE1 . GLU D 1 19  ? 318.382 272.709 86.671  1.00 82.91  ? 19  GLU D OE1 1 
ATOM 5450 O OE2 . GLU D 1 19  ? 319.868 271.179 87.192  1.00 82.91  ? 19  GLU D OE2 1 
ATOM 5451 N N   . ILE D 1 20  ? 317.223 269.253 85.625  1.00 78.64  ? 20  ILE D N   1 
ATOM 5452 C CA  . ILE D 1 20  ? 316.272 268.906 86.678  1.00 78.64  ? 20  ILE D CA  1 
ATOM 5453 C C   . ILE D 1 20  ? 315.871 267.436 86.588  1.00 78.64  ? 20  ILE D C   1 
ATOM 5454 O O   . ILE D 1 20  ? 315.659 266.776 87.619  1.00 78.64  ? 20  ILE D O   1 
ATOM 5455 C CB  . ILE D 1 20  ? 315.049 269.849 86.630  1.00 78.64  ? 20  ILE D CB  1 
ATOM 5456 C CG1 . ILE D 1 20  ? 314.369 269.831 85.256  1.00 78.64  ? 20  ILE D CG1 1 
ATOM 5457 C CG2 . ILE D 1 20  ? 315.440 271.261 87.028  1.00 78.64  ? 20  ILE D CG2 1 
ATOM 5458 C CD1 . ILE D 1 20  ? 312.900 270.172 85.290  1.00 78.64  ? 20  ILE D CD1 1 
ATOM 5459 N N   . GLU D 1 21  ? 315.806 266.889 85.370  1.00 81.17  ? 21  GLU D N   1 
ATOM 5460 C CA  . GLU D 1 21  ? 315.493 265.478 85.195  1.00 81.17  ? 21  GLU D CA  1 
ATOM 5461 C C   . GLU D 1 21  ? 316.639 264.604 85.679  1.00 81.17  ? 21  GLU D C   1 
ATOM 5462 O O   . GLU D 1 21  ? 316.408 263.590 86.340  1.00 81.17  ? 21  GLU D O   1 
ATOM 5463 C CB  . GLU D 1 21  ? 315.175 265.187 83.730  1.00 81.17  ? 21  GLU D CB  1 
ATOM 5464 C CG  . GLU D 1 21  ? 313.912 265.862 83.219  1.00 81.17  ? 21  GLU D CG  1 
ATOM 5465 C CD  . GLU D 1 21  ? 312.678 265.001 83.385  1.00 81.17  ? 21  GLU D CD  1 
ATOM 5466 O OE1 . GLU D 1 21  ? 311.576 265.469 83.032  1.00 81.17  ? 21  GLU D OE1 1 
ATOM 5467 O OE2 . GLU D 1 21  ? 312.809 263.853 83.855  1.00 81.17  ? 21  GLU D OE2 1 
ATOM 5468 N N   . GLU D 1 22  ? 317.882 265.002 85.386  1.00 88.23  ? 22  GLU D N   1 
ATOM 5469 C CA  . GLU D 1 22  ? 319.047 264.289 85.903  1.00 88.23  ? 22  GLU D CA  1 
ATOM 5470 C C   . GLU D 1 22  ? 319.144 264.418 87.419  1.00 88.23  ? 22  GLU D C   1 
ATOM 5471 O O   . GLU D 1 22  ? 319.525 263.462 88.099  1.00 88.23  ? 22  GLU D O   1 
ATOM 5472 C CB  . GLU D 1 22  ? 320.315 264.827 85.232  1.00 88.23  ? 22  GLU D CB  1 
ATOM 5473 C CG  . GLU D 1 22  ? 321.657 264.224 85.680  1.00 88.23  ? 22  GLU D CG  1 
ATOM 5474 C CD  . GLU D 1 22  ? 321.625 262.715 85.853  1.00 88.23  ? 22  GLU D CD  1 
ATOM 5475 O OE1 . GLU D 1 22  ? 321.822 262.231 86.988  1.00 88.23  ? 22  GLU D OE1 1 
ATOM 5476 O OE2 . GLU D 1 22  ? 321.398 262.010 84.849  1.00 88.23  ? 22  GLU D OE2 1 
ATOM 5477 N N   . LEU D 1 23  ? 318.740 265.570 87.959  1.00 86.27  ? 23  LEU D N   1 
ATOM 5478 C CA  . LEU D 1 23  ? 318.776 265.813 89.397  1.00 86.27  ? 23  LEU D CA  1 
ATOM 5479 C C   . LEU D 1 23  ? 317.814 264.883 90.132  1.00 86.27  ? 23  LEU D C   1 
ATOM 5480 O O   . LEU D 1 23  ? 318.214 264.135 91.038  1.00 86.27  ? 23  LEU D O   1 
ATOM 5481 C CB  . LEU D 1 23  ? 318.431 267.287 89.639  1.00 86.27  ? 23  LEU D CB  1 
ATOM 5482 C CG  . LEU D 1 23  ? 318.814 268.137 90.854  1.00 86.27  ? 23  LEU D CG  1 
ATOM 5483 C CD1 . LEU D 1 23  ? 318.418 269.586 90.599  1.00 86.27  ? 23  LEU D CD1 1 
ATOM 5484 C CD2 . LEU D 1 23  ? 318.216 267.656 92.152  1.00 86.27  ? 23  LEU D CD2 1 
ATOM 5485 N N   . ALA D 1 24  ? 316.541 264.891 89.735  1.00 83.09  ? 24  ALA D N   1 
ATOM 5486 C CA  . ALA D 1 24  ? 315.583 264.009 90.388  1.00 83.09  ? 24  ALA D CA  1 
ATOM 5487 C C   . ALA D 1 24  ? 315.749 262.549 89.971  1.00 83.09  ? 24  ALA D C   1 
ATOM 5488 O O   . ALA D 1 24  ? 315.316 261.662 90.709  1.00 83.09  ? 24  ALA D O   1 
ATOM 5489 C CB  . ALA D 1 24  ? 314.155 264.483 90.125  1.00 83.09  ? 24  ALA D CB  1 
ATOM 5490 N N   . ARG D 1 25  ? 316.418 262.271 88.848  1.00 89.45  ? 25  ARG D N   1 
ATOM 5491 C CA  . ARG D 1 25  ? 316.750 260.894 88.506  1.00 89.45  ? 25  ARG D CA  1 
ATOM 5492 C C   . ARG D 1 25  ? 317.843 260.355 89.415  1.00 89.45  ? 25  ARG D C   1 
ATOM 5493 O O   . ARG D 1 25  ? 317.786 259.193 89.840  1.00 89.45  ? 25  ARG D O   1 
ATOM 5494 C CB  . ARG D 1 25  ? 317.184 260.808 87.044  1.00 89.45  ? 25  ARG D CB  1 
ATOM 5495 C CG  . ARG D 1 25  ? 316.171 260.157 86.117  1.00 89.45  ? 25  ARG D CG  1 
ATOM 5496 C CD  . ARG D 1 25  ? 316.684 260.138 84.689  1.00 89.45  ? 25  ARG D CD  1 
ATOM 5497 N NE  . ARG D 1 25  ? 315.730 259.526 83.771  1.00 89.45  ? 25  ARG D NE  1 
ATOM 5498 C CZ  . ARG D 1 25  ? 315.793 258.264 83.359  1.00 89.45  ? 25  ARG D CZ  1 
ATOM 5499 N NH1 . ARG D 1 25  ? 316.769 257.473 83.782  1.00 89.45  ? 25  ARG D NH1 1 
ATOM 5500 N NH2 . ARG D 1 25  ? 314.880 257.795 82.522  1.00 89.45  ? 25  ARG D NH2 1 
ATOM 5501 N N   . PHE D 1 26  ? 318.849 261.184 89.714  1.00 92.29  ? 26  PHE D N   1 
ATOM 5502 C CA  . PHE D 1 26  ? 319.843 260.826 90.719  1.00 92.29  ? 26  PHE D CA  1 
ATOM 5503 C C   . PHE D 1 26  ? 319.192 260.644 92.079  1.00 92.29  ? 26  PHE D C   1 
ATOM 5504 O O   . PHE D 1 26  ? 319.555 259.730 92.831  1.00 92.29  ? 26  PHE D O   1 
ATOM 5505 C CB  . PHE D 1 26  ? 320.939 261.888 90.790  1.00 92.29  ? 26  PHE D CB  1 
ATOM 5506 C CG  . PHE D 1 26  ? 321.817 261.762 92.001  1.00 92.29  ? 26  PHE D CG  1 
ATOM 5507 C CD1 . PHE D 1 26  ? 322.679 260.684 92.135  1.00 92.29  ? 26  PHE D CD1 1 
ATOM 5508 C CD2 . PHE D 1 26  ? 321.771 262.711 93.013  1.00 92.29  ? 26  PHE D CD2 1 
ATOM 5509 C CE1 . PHE D 1 26  ? 323.487 260.558 93.250  1.00 92.29  ? 26  PHE D CE1 1 
ATOM 5510 C CE2 . PHE D 1 26  ? 322.575 262.587 94.131  1.00 92.29  ? 26  PHE D CE2 1 
ATOM 5511 C CZ  . PHE D 1 26  ? 323.436 261.512 94.246  1.00 92.29  ? 26  PHE D CZ  1 
ATOM 5512 N N   . ALA D 1 27  ? 318.197 261.484 92.387  1.00 83.30  ? 27  ALA D N   1 
ATOM 5513 C CA  . ALA D 1 27  ? 317.418 261.313 93.609  1.00 83.30  ? 27  ALA D CA  1 
ATOM 5514 C C   . ALA D 1 27  ? 316.665 259.985 93.622  1.00 83.30  ? 27  ALA D C   1 
ATOM 5515 O O   . ALA D 1 27  ? 316.594 259.316 94.659  1.00 83.30  ? 27  ALA D O   1 
ATOM 5516 C CB  . ALA D 1 27  ? 316.445 262.479 93.772  1.00 83.30  ? 27  ALA D CB  1 
ATOM 5517 N N   . VAL D 1 28  ? 316.127 259.561 92.476  1.00 84.85  ? 28  VAL D N   1 
ATOM 5518 C CA  . VAL D 1 28  ? 315.306 258.356 92.530  1.00 84.85  ? 28  VAL D CA  1 
ATOM 5519 C C   . VAL D 1 28  ? 316.177 257.094 92.554  1.00 84.85  ? 28  VAL D C   1 
ATOM 5520 O O   . VAL D 1 28  ? 315.820 256.123 93.233  1.00 84.85  ? 28  VAL D O   1 
ATOM 5521 C CB  . VAL D 1 28  ? 314.237 258.329 91.410  1.00 84.85  ? 28  VAL D CB  1 
ATOM 5522 C CG1 . VAL D 1 28  ? 314.797 258.027 90.033  1.00 84.85  ? 28  VAL D CG1 1 
ATOM 5523 C CG2 . VAL D 1 28  ? 313.123 257.356 91.756  1.00 84.85  ? 28  VAL D CG2 1 
ATOM 5524 N N   . ASP D 1 29  ? 317.359 257.086 91.907  1.00 90.48  ? 29  ASP D N   1 
ATOM 5525 C CA  . ASP D 1 29  ? 318.209 255.912 92.123  1.00 90.48  ? 29  ASP D CA  1 
ATOM 5526 C C   . ASP D 1 29  ? 318.887 255.945 93.485  1.00 90.48  ? 29  ASP D C   1 
ATOM 5527 O O   . ASP D 1 29  ? 319.214 254.874 94.017  1.00 90.48  ? 29  ASP D O   1 
ATOM 5528 C CB  . ASP D 1 29  ? 319.278 255.694 91.038  1.00 90.48  ? 29  ASP D CB  1 
ATOM 5529 C CG  . ASP D 1 29  ? 320.280 256.819 90.932  1.00 90.48  ? 29  ASP D CG  1 
ATOM 5530 O OD1 . ASP D 1 29  ? 320.105 257.676 90.059  1.00 90.48  ? 29  ASP D OD1 1 
ATOM 5531 O OD2 . ASP D 1 29  ? 321.261 256.842 91.704  1.00 90.48  ? 29  ASP D OD2 1 
ATOM 5532 N N   . GLU D 1 30  ? 319.075 257.142 94.064  1.00 89.29  ? 30  GLU D N   1 
ATOM 5533 C CA  . GLU D 1 30  ? 319.424 257.254 95.477  1.00 89.29  ? 30  GLU D CA  1 
ATOM 5534 C C   . GLU D 1 30  ? 318.403 256.546 96.351  1.00 89.29  ? 30  GLU D C   1 
ATOM 5535 O O   . GLU D 1 30  ? 318.779 255.787 97.249  1.00 89.29  ? 30  GLU D O   1 
ATOM 5536 C CB  . GLU D 1 30  ? 319.520 258.722 95.886  1.00 89.29  ? 30  GLU D CB  1 
ATOM 5537 C CG  . GLU D 1 30  ? 320.908 259.302 95.992  1.00 89.29  ? 30  GLU D CG  1 
ATOM 5538 C CD  . GLU D 1 30  ? 320.877 260.719 96.536  1.00 89.29  ? 30  GLU D CD  1 
ATOM 5539 O OE1 . GLU D 1 30  ? 319.799 261.349 96.490  1.00 89.29  ? 30  GLU D OE1 1 
ATOM 5540 O OE2 . GLU D 1 30  ? 321.920 261.200 97.024  1.00 89.29  ? 30  GLU D OE2 1 
ATOM 5541 N N   . HIS D 1 31  ? 317.109 256.775 96.086  1.00 86.78  ? 31  HIS D N   1 
ATOM 5542 C CA  . HIS D 1 31  ? 316.044 256.119 96.846  1.00 86.78  ? 31  HIS D CA  1 
ATOM 5543 C C   . HIS D 1 31  ? 316.077 254.604 96.666  1.00 86.78  ? 31  HIS D C   1 
ATOM 5544 O O   . HIS D 1 31  ? 316.046 253.854 97.653  1.00 86.78  ? 31  HIS D O   1 
ATOM 5545 C CB  . HIS D 1 31  ? 314.678 256.663 96.426  1.00 86.78  ? 31  HIS D CB  1 
ATOM 5546 C CG  . HIS D 1 31  ? 314.542 258.143 96.584  1.00 86.78  ? 31  HIS D CG  1 
ATOM 5547 N ND1 . HIS D 1 31  ? 315.293 258.869 97.482  1.00 86.78  ? 31  HIS D ND1 1 
ATOM 5548 C CD2 . HIS D 1 31  ? 313.754 259.036 95.942  1.00 86.78  ? 31  HIS D CD2 1 
ATOM 5549 C CE1 . HIS D 1 31  ? 314.967 260.146 97.393  1.00 86.78  ? 31  HIS D CE1 1 
ATOM 5550 N NE2 . HIS D 1 31  ? 314.036 260.274 96.466  1.00 86.78  ? 31  HIS D NE2 1 
ATOM 5551 N N   . ASN D 1 32  ? 316.178 254.142 95.407  1.00 85.51  ? 32  ASN D N   1 
ATOM 5552 C CA  . ASN D 1 32  ? 316.211 252.703 95.131  1.00 85.51  ? 32  ASN D CA  1 
ATOM 5553 C C   . ASN D 1 32  ? 317.448 252.030 95.716  1.00 85.51  ? 32  ASN D C   1 
ATOM 5554 O O   . ASN D 1 32  ? 317.441 250.814 95.942  1.00 85.51  ? 32  ASN D O   1 
ATOM 5555 C CB  . ASN D 1 32  ? 316.148 252.423 93.627  1.00 85.51  ? 32  ASN D CB  1 
ATOM 5556 C CG  . ASN D 1 32  ? 315.067 253.210 92.924  1.00 85.51  ? 32  ASN D CG  1 
ATOM 5557 O OD1 . ASN D 1 32  ? 313.902 253.163 93.303  1.00 85.51  ? 32  ASN D OD1 1 
ATOM 5558 N ND2 . ASN D 1 32  ? 315.448 253.933 91.879  1.00 85.51  ? 32  ASN D ND2 1 
ATOM 5559 N N   . LYS D 1 33  ? 318.511 252.794 95.975  1.00 86.92  ? 33  LYS D N   1 
ATOM 5560 C CA  . LYS D 1 33  ? 319.650 252.229 96.683  1.00 86.92  ? 33  LYS D CA  1 
ATOM 5561 C C   . LYS D 1 33  ? 319.434 252.208 98.198  1.00 86.92  ? 33  LYS D C   1 
ATOM 5562 O O   . LYS D 1 33  ? 319.636 251.169 98.837  1.00 86.92  ? 33  LYS D O   1 
ATOM 5563 C CB  . LYS D 1 33  ? 320.923 252.995 96.321  1.00 86.92  ? 33  LYS D CB  1 
ATOM 5564 C CG  . LYS D 1 33  ? 321.555 252.541 95.011  1.00 86.92  ? 33  LYS D CG  1 
ATOM 5565 C CD  . LYS D 1 33  ? 321.812 251.037 95.009  1.00 86.92  ? 33  LYS D CD  1 
ATOM 5566 C CE  . LYS D 1 33  ? 322.607 250.598 93.787  1.00 86.92  ? 33  LYS D CE  1 
ATOM 5567 N NZ  . LYS D 1 33  ? 322.909 249.138 93.806  1.00 86.92  ? 33  LYS D NZ  1 
ATOM 5568 N N   . LYS D 1 34  ? 319.007 253.328 98.799  1.00 80.54  ? 34  LYS D N   1 
ATOM 5569 C CA  . LYS D 1 34  ? 319.066 253.392 100.260 1.00 80.54  ? 34  LYS D CA  1 
ATOM 5570 C C   . LYS D 1 34  ? 317.867 252.761 100.957 1.00 80.54  ? 34  LYS D C   1 
ATOM 5571 O O   . LYS D 1 34  ? 318.054 252.102 101.987 1.00 80.54  ? 34  LYS D O   1 
ATOM 5572 C CB  . LYS D 1 34  ? 319.218 254.834 100.778 1.00 80.54  ? 34  LYS D CB  1 
ATOM 5573 C CG  . LYS D 1 34  ? 318.175 255.856 100.341 1.00 80.54  ? 34  LYS D CG  1 
ATOM 5574 C CD  . LYS D 1 34  ? 318.175 257.088 101.229 1.00 80.54  ? 34  LYS D CD  1 
ATOM 5575 C CE  . LYS D 1 34  ? 317.198 258.130 100.715 1.00 80.54  ? 34  LYS D CE  1 
ATOM 5576 N NZ  . LYS D 1 34  ? 315.921 257.526 100.253 1.00 80.54  ? 34  LYS D NZ  1 
ATOM 5577 N N   . GLU D 1 35  ? 316.639 252.934 100.457 1.00 76.80  ? 35  GLU D N   1 
ATOM 5578 C CA  . GLU D 1 35  ? 315.478 252.526 101.244 1.00 76.80  ? 35  GLU D CA  1 
ATOM 5579 C C   . GLU D 1 35  ? 314.762 251.309 100.677 1.00 76.80  ? 35  GLU D C   1 
ATOM 5580 O O   . GLU D 1 35  ? 313.626 251.038 101.088 1.00 76.80  ? 35  GLU D O   1 
ATOM 5581 C CB  . GLU D 1 35  ? 314.491 253.690 101.408 1.00 76.80  ? 35  GLU D CB  1 
ATOM 5582 C CG  . GLU D 1 35  ? 314.052 254.349 100.122 1.00 76.80  ? 35  GLU D CG  1 
ATOM 5583 C CD  . GLU D 1 35  ? 312.999 255.412 100.334 1.00 76.80  ? 35  GLU D CD  1 
ATOM 5584 O OE1 . GLU D 1 35  ? 313.110 256.163 101.326 1.00 76.80  ? 35  GLU D OE1 1 
ATOM 5585 O OE2 . GLU D 1 35  ? 312.063 255.497 99.509  1.00 76.80  ? 35  GLU D OE2 1 
ATOM 5586 N N   . ASN D 1 36  ? 315.422 250.553 99.793  1.00 70.55  ? 36  ASN D N   1 
ATOM 5587 C CA  . ASN D 1 36  ? 314.851 249.430 99.037  1.00 70.55  ? 36  ASN D CA  1 
ATOM 5588 C C   . ASN D 1 36  ? 313.557 249.852 98.339  1.00 70.55  ? 36  ASN D C   1 
ATOM 5589 O O   . ASN D 1 36  ? 312.458 249.379 98.636  1.00 70.55  ? 36  ASN D O   1 
ATOM 5590 C CB  . ASN D 1 36  ? 314.638 248.200 99.924  1.00 70.55  ? 36  ASN D CB  1 
ATOM 5591 C CG  . ASN D 1 36  ? 314.470 246.924 99.118  1.00 70.55  ? 36  ASN D CG  1 
ATOM 5592 O OD1 . ASN D 1 36  ? 313.426 246.684 98.516  1.00 70.55  ? 36  ASN D OD1 1 
ATOM 5593 N ND2 . ASN D 1 36  ? 315.510 246.104 99.098  1.00 70.55  ? 36  ASN D ND2 1 
ATOM 5594 N N   . ALA D 1 37  ? 313.710 250.798 97.424  1.00 76.97  ? 37  ALA D N   1 
ATOM 5595 C CA  . ALA D 1 37  ? 312.590 251.439 96.766  1.00 76.97  ? 37  ALA D CA  1 
ATOM 5596 C C   . ALA D 1 37  ? 312.589 251.088 95.286  1.00 76.97  ? 37  ALA D C   1 
ATOM 5597 O O   . ALA D 1 37  ? 313.578 250.597 94.736  1.00 76.97  ? 37  ALA D O   1 
ATOM 5598 C CB  . ALA D 1 37  ? 312.651 252.956 96.961  1.00 76.97  ? 37  ALA D CB  1 
ATOM 5599 N N   . LEU D 1 38  ? 311.450 251.333 94.642  1.00 82.04  ? 38  LEU D N   1 
ATOM 5600 C CA  . LEU D 1 38  ? 311.306 251.129 93.200  1.00 82.04  ? 38  LEU D CA  1 
ATOM 5601 C C   . LEU D 1 38  ? 310.279 252.163 92.739  1.00 82.04  ? 38  LEU D C   1 
ATOM 5602 O O   . LEU D 1 38  ? 309.068 251.946 92.836  1.00 82.04  ? 38  LEU D O   1 
ATOM 5603 C CB  . LEU D 1 38  ? 310.887 249.698 92.880  1.00 82.04  ? 38  LEU D CB  1 
ATOM 5604 C CG  . LEU D 1 38  ? 310.486 249.311 91.458  1.00 82.04  ? 38  LEU D CG  1 
ATOM 5605 C CD1 . LEU D 1 38  ? 311.691 249.423 90.535  1.00 82.04  ? 38  LEU D CD1 1 
ATOM 5606 C CD2 . LEU D 1 38  ? 309.902 247.904 91.436  1.00 82.04  ? 38  LEU D CD2 1 
ATOM 5607 N N   . LEU D 1 39  ? 310.775 253.304 92.268  1.00 84.11  ? 39  LEU D N   1 
ATOM 5608 C CA  . LEU D 1 39  ? 309.937 254.408 91.825  1.00 84.11  ? 39  LEU D CA  1 
ATOM 5609 C C   . LEU D 1 39  ? 310.375 254.840 90.435  1.00 84.11  ? 39  LEU D C   1 
ATOM 5610 O O   . LEU D 1 39  ? 311.572 254.865 90.131  1.00 84.11  ? 39  LEU D O   1 
ATOM 5611 C CB  . LEU D 1 39  ? 310.008 255.599 92.788  1.00 84.11  ? 39  LEU D CB  1 
ATOM 5612 C CG  . LEU D 1 39  ? 309.676 255.418 94.270  1.00 84.11  ? 39  LEU D CG  1 
ATOM 5613 C CD1 . LEU D 1 39  ? 310.927 255.583 95.088  1.00 84.11  ? 39  LEU D CD1 1 
ATOM 5614 C CD2 . LEU D 1 39  ? 308.623 256.406 94.714  1.00 84.11  ? 39  LEU D CD2 1 
ATOM 5615 N N   . GLU D 1 40  ? 309.402 255.164 89.589  1.00 86.81  ? 40  GLU D N   1 
ATOM 5616 C CA  . GLU D 1 40  ? 309.659 255.524 88.199  1.00 86.81  ? 40  GLU D CA  1 
ATOM 5617 C C   . GLU D 1 40  ? 309.395 257.017 88.035  1.00 86.81  ? 40  GLU D C   1 
ATOM 5618 O O   . GLU D 1 40  ? 308.309 257.438 87.636  1.00 86.81  ? 40  GLU D O   1 
ATOM 5619 C CB  . GLU D 1 40  ? 308.783 254.677 87.240  1.00 86.81  ? 40  GLU D CB  1 
ATOM 5620 C CG  . GLU D 1 40  ? 308.557 253.214 87.658  1.00 86.81  ? 40  GLU D CG  1 
ATOM 5621 C CD  . GLU D 1 40  ? 309.828 252.408 87.918  1.00 86.81  ? 40  GLU D CD  1 
ATOM 5622 O OE1 . GLU D 1 40  ? 310.883 252.675 87.296  1.00 86.81  ? 40  GLU D OE1 1 
ATOM 5623 O OE2 . GLU D 1 40  ? 309.766 251.496 88.767  1.00 86.81  ? 40  GLU D OE2 1 
ATOM 5624 N N   . PHE D 1 41  ? 310.411 257.820 88.340  1.00 87.86  ? 41  PHE D N   1 
ATOM 5625 C CA  . PHE D 1 41  ? 310.351 259.254 88.082  1.00 87.86  ? 41  PHE D CA  1 
ATOM 5626 C C   . PHE D 1 41  ? 310.427 259.494 86.577  1.00 87.86  ? 41  PHE D C   1 
ATOM 5627 O O   . PHE D 1 41  ? 311.418 259.129 85.935  1.00 87.86  ? 41  PHE D O   1 
ATOM 5628 C CB  . PHE D 1 41  ? 311.490 259.965 88.814  1.00 87.86  ? 41  PHE D CB  1 
ATOM 5629 C CG  . PHE D 1 41  ? 311.870 261.283 88.207  1.00 87.86  ? 41  PHE D CG  1 
ATOM 5630 C CD1 . PHE D 1 41  ? 311.049 262.386 88.357  1.00 87.86  ? 41  PHE D CD1 1 
ATOM 5631 C CD2 . PHE D 1 41  ? 313.049 261.419 87.485  1.00 87.86  ? 41  PHE D CD2 1 
ATOM 5632 C CE1 . PHE D 1 41  ? 311.393 263.593 87.798  1.00 87.86  ? 41  PHE D CE1 1 
ATOM 5633 C CE2 . PHE D 1 41  ? 313.390 262.628 86.918  1.00 87.86  ? 41  PHE D CE2 1 
ATOM 5634 C CZ  . PHE D 1 41  ? 312.557 263.715 87.069  1.00 87.86  ? 41  PHE D CZ  1 
ATOM 5635 N N   . VAL D 1 42  ? 309.381 260.095 86.006  1.00 85.92  ? 42  VAL D N   1 
ATOM 5636 C CA  . VAL D 1 42  ? 309.300 260.221 84.554  1.00 85.92  ? 42  VAL D CA  1 
ATOM 5637 C C   . VAL D 1 42  ? 309.258 261.676 84.093  1.00 85.92  ? 42  VAL D C   1 
ATOM 5638 O O   . VAL D 1 42  ? 309.659 261.980 82.964  1.00 85.92  ? 42  VAL D O   1 
ATOM 5639 C CB  . VAL D 1 42  ? 308.095 259.432 83.991  1.00 85.92  ? 42  VAL D CB  1 
ATOM 5640 C CG1 . VAL D 1 42  ? 308.191 257.960 84.359  1.00 85.92  ? 42  VAL D CG1 1 
ATOM 5641 C CG2 . VAL D 1 42  ? 306.773 259.996 84.497  1.00 85.92  ? 42  VAL D CG2 1 
ATOM 5642 N N   . ARG D 1 43  ? 308.799 262.589 84.950  1.00 87.36  ? 43  ARG D N   1 
ATOM 5643 C CA  . ARG D 1 43  ? 308.587 263.965 84.520  1.00 87.36  ? 43  ARG D CA  1 
ATOM 5644 C C   . ARG D 1 43  ? 308.594 264.895 85.723  1.00 87.36  ? 43  ARG D C   1 
ATOM 5645 O O   . ARG D 1 43  ? 308.506 264.459 86.872  1.00 87.36  ? 43  ARG D O   1 
ATOM 5646 C CB  . ARG D 1 43  ? 307.269 264.114 83.746  1.00 87.36  ? 43  ARG D CB  1 
ATOM 5647 C CG  . ARG D 1 43  ? 306.041 263.674 84.523  1.00 87.36  ? 43  ARG D CG  1 
ATOM 5648 C CD  . ARG D 1 43  ? 304.758 264.184 83.886  1.00 87.36  ? 43  ARG D CD  1 
ATOM 5649 N NE  . ARG D 1 43  ? 304.665 265.641 83.907  1.00 87.36  ? 43  ARG D NE  1 
ATOM 5650 C CZ  . ARG D 1 43  ? 303.708 266.336 83.299  1.00 87.36  ? 43  ARG D CZ  1 
ATOM 5651 N NH1 . ARG D 1 43  ? 302.759 265.706 82.619  1.00 87.36  ? 43  ARG D NH1 1 
ATOM 5652 N NH2 . ARG D 1 43  ? 303.701 267.659 83.366  1.00 87.36  ? 43  ARG D NH2 1 
ATOM 5653 N N   . VAL D 1 44  ? 308.700 266.191 85.436  1.00 80.56  ? 44  VAL D N   1 
ATOM 5654 C CA  . VAL D 1 44  ? 308.678 267.247 86.443  1.00 80.56  ? 44  VAL D CA  1 
ATOM 5655 C C   . VAL D 1 44  ? 307.581 268.231 86.062  1.00 80.56  ? 44  VAL D C   1 
ATOM 5656 O O   . VAL D 1 44  ? 307.585 268.768 84.947  1.00 80.56  ? 44  VAL D O   1 
ATOM 5657 C CB  . VAL D 1 44  ? 310.032 267.971 86.554  1.00 80.56  ? 44  VAL D CB  1 
ATOM 5658 C CG1 . VAL D 1 44  ? 309.894 269.244 87.369  1.00 80.56  ? 44  VAL D CG1 1 
ATOM 5659 C CG2 . VAL D 1 44  ? 311.076 267.077 87.174  1.00 80.56  ? 44  VAL D CG2 1 
ATOM 5660 N N   . VAL D 1 45  ? 306.638 268.460 86.977  1.00 80.59  ? 45  VAL D N   1 
ATOM 5661 C CA  . VAL D 1 45  ? 305.689 269.556 86.800  1.00 80.59  ? 45  VAL D CA  1 
ATOM 5662 C C   . VAL D 1 45  ? 306.266 270.853 87.355  1.00 80.59  ? 45  VAL D C   1 
ATOM 5663 O O   . VAL D 1 45  ? 306.213 271.901 86.701  1.00 80.59  ? 45  VAL D O   1 
ATOM 5664 C CB  . VAL D 1 45  ? 304.337 269.208 87.454  1.00 80.59  ? 45  VAL D CB  1 
ATOM 5665 C CG1 . VAL D 1 45  ? 303.372 270.384 87.365  1.00 80.59  ? 45  VAL D CG1 1 
ATOM 5666 C CG2 . VAL D 1 45  ? 303.722 267.989 86.791  1.00 80.59  ? 45  VAL D CG2 1 
ATOM 5667 N N   . LYS D 1 46  ? 306.846 270.798 88.551  1.00 82.45  ? 46  LYS D N   1 
ATOM 5668 C CA  . LYS D 1 46  ? 307.355 271.984 89.226  1.00 82.45  ? 46  LYS D CA  1 
ATOM 5669 C C   . LYS D 1 46  ? 308.773 271.720 89.711  1.00 82.45  ? 46  LYS D C   1 
ATOM 5670 O O   . LYS D 1 46  ? 309.049 270.667 90.294  1.00 82.45  ? 46  LYS D O   1 
ATOM 5671 C CB  . LYS D 1 46  ? 306.413 272.381 90.379  1.00 82.45  ? 46  LYS D CB  1 
ATOM 5672 C CG  . LYS D 1 46  ? 306.972 273.294 91.468  1.00 82.45  ? 46  LYS D CG  1 
ATOM 5673 C CD  . LYS D 1 46  ? 307.363 272.523 92.728  1.00 82.45  ? 46  LYS D CD  1 
ATOM 5674 C CE  . LYS D 1 46  ? 308.086 273.415 93.714  1.00 82.45  ? 46  LYS D CE  1 
ATOM 5675 N NZ  . LYS D 1 46  ? 308.737 272.624 94.790  1.00 82.45  ? 46  LYS D NZ  1 
ATOM 5676 N N   . ALA D 1 47  ? 309.668 272.673 89.459  1.00 83.21  ? 47  ALA D N   1 
ATOM 5677 C CA  . ALA D 1 47  ? 311.036 272.626 89.971  1.00 83.21  ? 47  ALA D CA  1 
ATOM 5678 C C   . ALA D 1 47  ? 311.483 274.056 90.238  1.00 83.21  ? 47  ALA D C   1 
ATOM 5679 O O   . ALA D 1 47  ? 311.853 274.775 89.304  1.00 83.21  ? 47  ALA D O   1 
ATOM 5680 C CB  . ALA D 1 47  ? 311.982 271.932 88.992  1.00 83.21  ? 47  ALA D CB  1 
ATOM 5681 N N   . LYS D 1 48  ? 311.450 274.467 91.503  1.00 85.24  ? 48  LYS D N   1 
ATOM 5682 C CA  . LYS D 1 48  ? 311.851 275.819 91.858  1.00 85.24  ? 48  LYS D CA  1 
ATOM 5683 C C   . LYS D 1 48  ? 313.366 275.967 91.823  1.00 85.24  ? 48  LYS D C   1 
ATOM 5684 O O   . LYS D 1 48  ? 314.116 275.022 92.080  1.00 85.24  ? 48  LYS D O   1 
ATOM 5685 C CB  . LYS D 1 48  ? 311.338 276.190 93.249  1.00 85.24  ? 48  LYS D CB  1 
ATOM 5686 C CG  . LYS D 1 48  ? 309.883 276.617 93.308  1.00 85.24  ? 48  LYS D CG  1 
ATOM 5687 C CD  . LYS D 1 48  ? 309.582 277.253 94.650  1.00 85.24  ? 48  LYS D CD  1 
ATOM 5688 C CE  . LYS D 1 48  ? 310.067 278.689 94.685  1.00 85.24  ? 48  LYS D CE  1 
ATOM 5689 N NZ  . LYS D 1 48  ? 310.581 279.065 96.027  1.00 85.24  ? 48  LYS D NZ  1 
ATOM 5690 N N   . GLU D 1 49  ? 313.808 277.177 91.495  1.00 90.53  ? 49  GLU D N   1 
ATOM 5691 C CA  . GLU D 1 49  ? 315.213 277.554 91.526  1.00 90.53  ? 49  GLU D CA  1 
ATOM 5692 C C   . GLU D 1 49  ? 315.371 278.725 92.483  1.00 90.53  ? 49  GLU D C   1 
ATOM 5693 O O   . GLU D 1 49  ? 314.587 279.678 92.435  1.00 90.53  ? 49  GLU D O   1 
ATOM 5694 C CB  . GLU D 1 49  ? 315.720 277.932 90.129  1.00 90.53  ? 49  GLU D CB  1 
ATOM 5695 C CG  . GLU D 1 49  ? 315.222 277.027 89.009  1.00 90.53  ? 49  GLU D CG  1 
ATOM 5696 C CD  . GLU D 1 49  ? 316.157 277.005 87.815  1.00 90.53  ? 49  GLU D CD  1 
ATOM 5697 O OE1 . GLU D 1 49  ? 316.644 278.084 87.419  1.00 90.53  ? 49  GLU D OE1 1 
ATOM 5698 O OE2 . GLU D 1 49  ? 316.412 275.906 87.279  1.00 90.53  ? 49  GLU D OE2 1 
ATOM 5699 N N   . GLN D 1 50  ? 316.374 278.649 93.354  1.00 91.44  ? 50  GLN D N   1 
ATOM 5700 C CA  . GLN D 1 50  ? 316.601 279.703 94.341  1.00 91.44  ? 50  GLN D CA  1 
ATOM 5701 C C   . GLN D 1 50  ? 318.068 279.687 94.732  1.00 91.44  ? 50  GLN D C   1 
ATOM 5702 O O   . GLN D 1 50  ? 318.570 278.660 95.197  1.00 91.44  ? 50  GLN D O   1 
ATOM 5703 C CB  . GLN D 1 50  ? 315.706 279.504 95.568  1.00 91.44  ? 50  GLN D CB  1 
ATOM 5704 C CG  . GLN D 1 50  ? 315.663 280.698 96.505  1.00 91.44  ? 50  GLN D CG  1 
ATOM 5705 C CD  . GLN D 1 50  ? 316.429 280.454 97.787  1.00 91.44  ? 50  GLN D CD  1 
ATOM 5706 O OE1 . GLN D 1 50  ? 316.148 279.508 98.520  1.00 91.44  ? 50  GLN D OE1 1 
ATOM 5707 N NE2 . GLN D 1 50  ? 317.410 281.304 98.061  1.00 91.44  ? 50  GLN D NE2 1 
ATOM 5708 N N   . ILE D 1 51  ? 318.751 280.815 94.549  1.00 87.34  ? 51  ILE D N   1 
ATOM 5709 C CA  . ILE D 1 51  ? 320.164 280.947 94.886  1.00 87.34  ? 51  ILE D CA  1 
ATOM 5710 C C   . ILE D 1 51  ? 320.274 281.453 96.321  1.00 87.34  ? 51  ILE D C   1 
ATOM 5711 O O   . ILE D 1 51  ? 319.359 282.113 96.835  1.00 87.34  ? 51  ILE D O   1 
ATOM 5712 C CB  . ILE D 1 51  ? 320.891 281.868 93.877  1.00 87.34  ? 51  ILE D CB  1 
ATOM 5713 C CG1 . ILE D 1 51  ? 322.408 281.634 93.896  1.00 87.34  ? 51  ILE D CG1 1 
ATOM 5714 C CG2 . ILE D 1 51  ? 320.558 283.343 94.097  1.00 87.34  ? 51  ILE D CG2 1 
ATOM 5715 C CD1 . ILE D 1 51  ? 323.132 282.220 92.703  1.00 87.34  ? 51  ILE D CD1 1 
ATOM 5716 N N   . ILE D 1 52  ? 321.363 281.089 96.992  1.00 92.55  ? 52  ILE D N   1 
ATOM 5717 C CA  . ILE D 1 52  ? 321.588 281.502 98.369  1.00 92.55  ? 52  ILE D CA  1 
ATOM 5718 C C   . ILE D 1 52  ? 322.631 282.614 98.413  1.00 92.55  ? 52  ILE D C   1 
ATOM 5719 O O   . ILE D 1 52  ? 323.689 282.511 97.790  1.00 92.55  ? 52  ILE D O   1 
ATOM 5720 C CB  . ILE D 1 52  ? 322.017 280.312 99.247  1.00 92.55  ? 52  ILE D CB  1 
ATOM 5721 C CG1 . ILE D 1 52  ? 321.244 279.051 98.852  1.00 92.55  ? 52  ILE D CG1 1 
ATOM 5722 C CG2 . ILE D 1 52  ? 321.811 280.635 100.723 1.00 92.55  ? 52  ILE D CG2 1 
ATOM 5723 C CD1 . ILE D 1 52  ? 321.602 277.831 99.669  1.00 92.55  ? 52  ILE D CD1 1 
ATOM 5724 N N   . ASP D 1 59  ? 326.293 278.147 95.464  1.00 92.61  ? 59  ASP D N   1 
ATOM 5725 C CA  . ASP D 1 59  ? 325.304 277.132 95.808  1.00 92.61  ? 59  ASP D CA  1 
ATOM 5726 C C   . ASP D 1 59  ? 323.880 277.674 95.703  1.00 92.61  ? 59  ASP D C   1 
ATOM 5727 O O   . ASP D 1 59  ? 323.599 278.806 96.098  1.00 92.61  ? 59  ASP D O   1 
ATOM 5728 C CB  . ASP D 1 59  ? 325.575 276.582 97.214  1.00 92.61  ? 59  ASP D CB  1 
ATOM 5729 C CG  . ASP D 1 59  ? 325.813 277.676 98.243  1.00 92.61  ? 59  ASP D CG  1 
ATOM 5730 O OD1 . ASP D 1 59  ? 326.972 277.831 98.682  1.00 92.61  ? 59  ASP D OD1 1 
ATOM 5731 O OD2 . ASP D 1 59  ? 324.847 278.361 98.638  1.00 92.61  ? 59  ASP D OD2 1 
ATOM 5732 N N   . THR D 1 60  ? 322.989 276.867 95.132  1.00 94.19  ? 60  THR D N   1 
ATOM 5733 C CA  . THR D 1 60  ? 321.582 277.213 95.002  1.00 94.19  ? 60  THR D CA  1 
ATOM 5734 C C   . THR D 1 60  ? 320.741 276.201 95.768  1.00 94.19  ? 60  THR D C   1 
ATOM 5735 O O   . THR D 1 60  ? 321.195 275.094 96.069  1.00 94.19  ? 60  THR D O   1 
ATOM 5736 C CB  . THR D 1 60  ? 321.132 277.256 93.528  1.00 94.19  ? 60  THR D CB  1 
ATOM 5737 O OG1 . THR D 1 60  ? 321.022 275.925 93.015  1.00 94.19  ? 60  THR D OG1 1 
ATOM 5738 C CG2 . THR D 1 60  ? 322.118 278.043 92.674  1.00 94.19  ? 60  THR D CG2 1 
ATOM 5739 N N   . MET D 1 61  ? 319.512 276.596 96.096  1.00 99.94  ? 61  MET D N   1 
ATOM 5740 C CA  . MET D 1 61  ? 318.588 275.742 96.842  1.00 99.94  ? 61  MET D CA  1 
ATOM 5741 C C   . MET D 1 61  ? 317.427 275.376 95.922  1.00 99.94  ? 61  MET D C   1 
ATOM 5742 O O   . MET D 1 61  ? 316.423 276.083 95.846  1.00 99.94  ? 61  MET D O   1 
ATOM 5743 C CB  . MET D 1 61  ? 318.104 276.436 98.108  1.00 99.94  ? 61  MET D CB  1 
ATOM 5744 C CG  . MET D 1 61  ? 317.684 275.468 99.194  1.00 99.94  ? 61  MET D CG  1 
ATOM 5745 S SD  . MET D 1 61  ? 318.919 274.173 99.428  1.00 99.94  ? 61  MET D SD  1 
ATOM 5746 C CE  . MET D 1 61  ? 317.956 272.705 99.087  1.00 99.94  ? 61  MET D CE  1 
ATOM 5747 N N   . TYR D 1 62  ? 317.573 274.254 95.220  1.00 99.17  ? 62  TYR D N   1 
ATOM 5748 C CA  . TYR D 1 62  ? 316.529 273.761 94.335  1.00 99.17  ? 62  TYR D CA  1 
ATOM 5749 C C   . TYR D 1 62  ? 315.366 273.194 95.141  1.00 99.17  ? 62  TYR D C   1 
ATOM 5750 O O   . TYR D 1 62  ? 315.556 272.631 96.223  1.00 99.17  ? 62  TYR D O   1 
ATOM 5751 C CB  . TYR D 1 62  ? 317.083 272.677 93.408  1.00 99.17  ? 62  TYR D CB  1 
ATOM 5752 C CG  . TYR D 1 62  ? 317.672 273.185 92.111  1.00 99.17  ? 62  TYR D CG  1 
ATOM 5753 C CD1 . TYR D 1 62  ? 319.034 273.443 91.998  1.00 99.17  ? 62  TYR D CD1 1 
ATOM 5754 C CD2 . TYR D 1 62  ? 316.869 273.391 90.994  1.00 99.17  ? 62  TYR D CD2 1 
ATOM 5755 C CE1 . TYR D 1 62  ? 319.580 273.901 90.810  1.00 99.17  ? 62  TYR D CE1 1 
ATOM 5756 C CE2 . TYR D 1 62  ? 317.406 273.850 89.802  1.00 99.17  ? 62  TYR D CE2 1 
ATOM 5757 C CZ  . TYR D 1 62  ? 318.761 274.103 89.718  1.00 99.17  ? 62  TYR D CZ  1 
ATOM 5758 O OH  . TYR D 1 62  ? 319.303 274.559 88.538  1.00 99.17  ? 62  TYR D OH  1 
ATOM 5759 N N   . TYR D 1 63  ? 314.156 273.346 94.605  1.00 93.98  ? 63  TYR D N   1 
ATOM 5760 C CA  . TYR D 1 63  ? 312.957 272.735 95.171  1.00 93.98  ? 63  TYR D CA  1 
ATOM 5761 C C   . TYR D 1 63  ? 312.159 272.125 94.029  1.00 93.98  ? 63  TYR D C   1 
ATOM 5762 O O   . TYR D 1 63  ? 311.479 272.841 93.289  1.00 93.98  ? 63  TYR D O   1 
ATOM 5763 C CB  . TYR D 1 63  ? 312.117 273.751 95.944  1.00 93.98  ? 63  TYR D CB  1 
ATOM 5764 C CG  . TYR D 1 63  ? 312.794 274.305 97.177  1.00 93.98  ? 63  TYR D CG  1 
ATOM 5765 C CD1 . TYR D 1 63  ? 313.445 275.534 97.144  1.00 93.98  ? 63  TYR D CD1 1 
ATOM 5766 C CD2 . TYR D 1 63  ? 312.777 273.602 98.376  1.00 93.98  ? 63  TYR D CD2 1 
ATOM 5767 C CE1 . TYR D 1 63  ? 314.062 276.046 98.271  1.00 93.98  ? 63  TYR D CE1 1 
ATOM 5768 C CE2 . TYR D 1 63  ? 313.393 274.107 99.507  1.00 93.98  ? 63  TYR D CE2 1 
ATOM 5769 C CZ  . TYR D 1 63  ? 314.032 275.328 99.448  1.00 93.98  ? 63  TYR D CZ  1 
ATOM 5770 O OH  . TYR D 1 63  ? 314.644 275.832 100.570 1.00 93.98  ? 63  TYR D OH  1 
ATOM 5771 N N   . LEU D 1 64  ? 312.237 270.806 93.892  1.00 86.00  ? 64  LEU D N   1 
ATOM 5772 C CA  . LEU D 1 64  ? 311.590 270.076 92.816  1.00 86.00  ? 64  LEU D CA  1 
ATOM 5773 C C   . LEU D 1 64  ? 310.517 269.168 93.397  1.00 86.00  ? 64  LEU D C   1 
ATOM 5774 O O   . LEU D 1 64  ? 310.574 268.792 94.569  1.00 86.00  ? 64  LEU D O   1 
ATOM 5775 C CB  . LEU D 1 64  ? 312.599 269.221 92.028  1.00 86.00  ? 64  LEU D CB  1 
ATOM 5776 C CG  . LEU D 1 64  ? 313.945 269.802 91.587  1.00 86.00  ? 64  LEU D CG  1 
ATOM 5777 C CD1 . LEU D 1 64  ? 315.030 269.497 92.606  1.00 86.00  ? 64  LEU D CD1 1 
ATOM 5778 C CD2 . LEU D 1 64  ? 314.335 269.242 90.236  1.00 86.00  ? 64  LEU D CD2 1 
ATOM 5779 N N   . THR D 1 65  ? 309.531 268.819 92.580  1.00 79.27  ? 65  THR D N   1 
ATOM 5780 C CA  . THR D 1 65  ? 308.624 267.729 92.906  1.00 79.27  ? 65  THR D CA  1 
ATOM 5781 C C   . THR D 1 65  ? 308.825 266.615 91.889  1.00 79.27  ? 65  THR D C   1 
ATOM 5782 O O   . THR D 1 65  ? 309.045 266.877 90.701  1.00 79.27  ? 65  THR D O   1 
ATOM 5783 C CB  . THR D 1 65  ? 307.158 268.188 92.968  1.00 79.27  ? 65  THR D CB  1 
ATOM 5784 O OG1 . THR D 1 65  ? 306.325 267.074 93.314  1.00 79.27  ? 65  THR D OG1 1 
ATOM 5785 C CG2 . THR D 1 65  ? 306.669 268.815 91.660  1.00 79.27  ? 65  THR D CG2 1 
ATOM 5786 N N   . LEU D 1 66  ? 308.824 265.378 92.367  1.00 79.31  ? 66  LEU D N   1 
ATOM 5787 C CA  . LEU D 1 66  ? 309.013 264.220 91.509  1.00 79.31  ? 66  LEU D CA  1 
ATOM 5788 C C   . LEU D 1 66  ? 307.798 263.310 91.619  1.00 79.31  ? 66  LEU D C   1 
ATOM 5789 O O   . LEU D 1 66  ? 307.419 262.888 92.717  1.00 79.31  ? 66  LEU D O   1 
ATOM 5790 C CB  . LEU D 1 66  ? 310.319 263.479 91.840  1.00 79.31  ? 66  LEU D CB  1 
ATOM 5791 C CG  . LEU D 1 66  ? 310.628 262.651 93.093  1.00 79.31  ? 66  LEU D CG  1 
ATOM 5792 C CD1 . LEU D 1 66  ? 311.838 261.759 92.842  1.00 79.31  ? 66  LEU D CD1 1 
ATOM 5793 C CD2 . LEU D 1 66  ? 310.868 263.538 94.301  1.00 79.31  ? 66  LEU D CD2 1 
ATOM 5794 N N   . GLU D 1 67  ? 307.164 263.059 90.481  1.00 85.22  ? 67  GLU D N   1 
ATOM 5795 C CA  . GLU D 1 67  ? 306.008 262.181 90.390  1.00 85.22  ? 67  GLU D CA  1 
ATOM 5796 C C   . GLU D 1 67  ? 306.485 260.834 89.863  1.00 85.22  ? 67  GLU D C   1 
ATOM 5797 O O   . GLU D 1 67  ? 307.150 260.766 88.823  1.00 85.22  ? 67  GLU D O   1 
ATOM 5798 C CB  . GLU D 1 67  ? 304.921 262.795 89.503  1.00 85.22  ? 67  GLU D CB  1 
ATOM 5799 C CG  . GLU D 1 67  ? 305.402 263.415 88.193  1.00 85.22  ? 67  GLU D CG  1 
ATOM 5800 C CD  . GLU D 1 67  ? 305.758 264.886 88.322  1.00 85.22  ? 67  GLU D CD  1 
ATOM 5801 O OE1 . GLU D 1 67  ? 305.950 265.367 89.459  1.00 85.22  ? 67  GLU D OE1 1 
ATOM 5802 O OE2 . GLU D 1 67  ? 305.860 265.559 87.278  1.00 85.22  ? 67  GLU D OE2 1 
ATOM 5803 N N   . ALA D 1 68  ? 306.183 259.773 90.603  1.00 79.64  ? 68  ALA D N   1 
ATOM 5804 C CA  . ALA D 1 68  ? 306.770 258.470 90.343  1.00 79.64  ? 68  ALA D CA  1 
ATOM 5805 C C   . ALA D 1 68  ? 305.730 257.369 90.470  1.00 79.64  ? 68  ALA D C   1 
ATOM 5806 O O   . ALA D 1 68  ? 304.867 257.414 91.353  1.00 79.64  ? 68  ALA D O   1 
ATOM 5807 C CB  . ALA D 1 68  ? 307.928 258.202 91.294  1.00 79.64  ? 68  ALA D CB  1 
ATOM 5808 N N   . LYS D 1 69  ? 305.821 256.381 89.581  1.00 82.36  ? 69  LYS D N   1 
ATOM 5809 C CA  . LYS D 1 69  ? 304.987 255.195 89.695  1.00 82.36  ? 69  LYS D CA  1 
ATOM 5810 C C   . LYS D 1 69  ? 305.465 254.332 90.856  1.00 82.36  ? 69  LYS D C   1 
ATOM 5811 O O   . LYS D 1 69  ? 306.648 253.993 90.952  1.00 82.36  ? 69  LYS D O   1 
ATOM 5812 C CB  . LYS D 1 69  ? 305.026 254.385 88.401  1.00 82.36  ? 69  LYS D CB  1 
ATOM 5813 C CG  . LYS D 1 69  ? 304.252 254.986 87.242  1.00 82.36  ? 69  LYS D CG  1 
ATOM 5814 C CD  . LYS D 1 69  ? 304.939 254.667 85.921  1.00 82.36  ? 69  LYS D CD  1 
ATOM 5815 C CE  . LYS D 1 69  ? 304.506 255.604 84.808  1.00 82.36  ? 69  LYS D CE  1 
ATOM 5816 N NZ  . LYS D 1 69  ? 304.920 257.011 85.045  1.00 82.36  ? 69  LYS D NZ  1 
ATOM 5817 N N   . ASP D 1 70  ? 304.543 253.986 91.750  1.00 80.86  ? 70  ASP D N   1 
ATOM 5818 C CA  . ASP D 1 70  ? 304.824 253.101 92.879  1.00 80.86  ? 70  ASP D CA  1 
ATOM 5819 C C   . ASP D 1 70  ? 304.161 251.762 92.569  1.00 80.86  ? 70  ASP D C   1 
ATOM 5820 O O   . ASP D 1 70  ? 303.019 251.514 92.964  1.00 80.86  ? 70  ASP D O   1 
ATOM 5821 C CB  . ASP D 1 70  ? 304.322 253.693 94.188  1.00 80.86  ? 70  ASP D CB  1 
ATOM 5822 C CG  . ASP D 1 70  ? 305.060 254.958 94.574  1.00 80.86  ? 70  ASP D CG  1 
ATOM 5823 O OD1 . ASP D 1 70  ? 305.516 255.685 93.667  1.00 80.86  ? 70  ASP D OD1 1 
ATOM 5824 O OD2 . ASP D 1 70  ? 305.192 255.223 95.787  1.00 80.86  ? 70  ASP D OD2 1 
ATOM 5825 N N   . GLY D 1 71  ? 304.884 250.897 91.863  1.00 67.46  ? 71  GLY D N   1 
ATOM 5826 C CA  . GLY D 1 71  ? 304.270 249.703 91.316  1.00 67.46  ? 71  GLY D CA  1 
ATOM 5827 C C   . GLY D 1 71  ? 303.285 249.996 90.208  1.00 67.46  ? 71  GLY D C   1 
ATOM 5828 O O   . GLY D 1 71  ? 302.351 249.216 89.992  1.00 67.46  ? 71  GLY D O   1 
ATOM 5829 N N   . GLY D 1 72  ? 303.473 251.108 89.496  1.00 71.20  ? 72  GLY D N   1 
ATOM 5830 C CA  . GLY D 1 72  ? 302.532 251.582 88.506  1.00 71.20  ? 72  GLY D CA  1 
ATOM 5831 C C   . GLY D 1 72  ? 301.605 252.677 88.992  1.00 71.20  ? 72  GLY D C   1 
ATOM 5832 O O   . GLY D 1 72  ? 300.873 253.250 88.176  1.00 71.20  ? 72  GLY D O   1 
ATOM 5833 N N   . LYS D 1 73  ? 301.620 252.989 90.286  1.00 75.26  ? 73  LYS D N   1 
ATOM 5834 C CA  . LYS D 1 73  ? 300.697 253.946 90.881  1.00 75.26  ? 73  LYS D CA  1 
ATOM 5835 C C   . LYS D 1 73  ? 301.407 255.263 91.162  1.00 75.26  ? 73  LYS D C   1 
ATOM 5836 O O   . LYS D 1 73  ? 302.443 255.286 91.834  1.00 75.26  ? 73  LYS D O   1 
ATOM 5837 C CB  . LYS D 1 73  ? 300.094 253.387 92.170  1.00 75.26  ? 73  LYS D CB  1 
ATOM 5838 C CG  . LYS D 1 73  ? 299.174 252.189 91.971  1.00 75.26  ? 73  LYS D CG  1 
ATOM 5839 C CD  . LYS D 1 73  ? 298.298 252.343 90.733  1.00 75.26  ? 73  LYS D CD  1 
ATOM 5840 C CE  . LYS D 1 73  ? 297.194 251.307 90.689  1.00 75.26  ? 73  LYS D CE  1 
ATOM 5841 N NZ  . LYS D 1 73  ? 296.121 251.732 89.757  1.00 75.26  ? 73  LYS D NZ  1 
ATOM 5842 N N   . LYS D 1 74  ? 300.831 256.355 90.668  1.00 81.18  ? 74  LYS D N   1 
ATOM 5843 C CA  . LYS D 1 74  ? 301.467 257.662 90.744  1.00 81.18  ? 74  LYS D CA  1 
ATOM 5844 C C   . LYS D 1 74  ? 301.302 258.268 92.133  1.00 81.18  ? 74  LYS D C   1 
ATOM 5845 O O   . LYS D 1 74  ? 300.318 258.004 92.830  1.00 81.18  ? 74  LYS D O   1 
ATOM 5846 C CB  . LYS D 1 74  ? 300.875 258.589 89.676  1.00 81.18  ? 74  LYS D CB  1 
ATOM 5847 C CG  . LYS D 1 74  ? 301.683 259.849 89.356  1.00 81.18  ? 74  LYS D CG  1 
ATOM 5848 C CD  . LYS D 1 74  ? 303.171 259.588 89.102  1.00 81.18  ? 74  LYS D CD  1 
ATOM 5849 C CE  . LYS D 1 74  ? 303.452 258.705 87.887  1.00 81.18  ? 74  LYS D CE  1 
ATOM 5850 N NZ  . LYS D 1 74  ? 304.877 258.834 87.481  1.00 81.18  ? 74  LYS D NZ  1 
ATOM 5851 N N   . LYS D 1 75  ? 302.282 259.079 92.533  1.00 80.47  ? 75  LYS D N   1 
ATOM 5852 C CA  . LYS D 1 75  ? 302.293 259.725 93.839  1.00 80.47  ? 75  LYS D CA  1 
ATOM 5853 C C   . LYS D 1 75  ? 303.177 260.961 93.746  1.00 80.47  ? 75  LYS D C   1 
ATOM 5854 O O   . LYS D 1 75  ? 304.308 260.877 93.256  1.00 80.47  ? 75  LYS D O   1 
ATOM 5855 C CB  . LYS D 1 75  ? 302.809 258.763 94.916  1.00 80.47  ? 75  LYS D CB  1 
ATOM 5856 C CG  . LYS D 1 75  ? 302.904 259.330 96.324  1.00 80.47  ? 75  LYS D CG  1 
ATOM 5857 C CD  . LYS D 1 75  ? 301.650 260.072 96.749  1.00 80.47  ? 75  LYS D CD  1 
ATOM 5858 C CE  . LYS D 1 75  ? 301.959 261.018 97.894  1.00 80.47  ? 75  LYS D CE  1 
ATOM 5859 N NZ  . LYS D 1 75  ? 302.320 260.266 99.126  1.00 80.47  ? 75  LYS D NZ  1 
ATOM 5860 N N   . LEU D 1 76  ? 302.662 262.098 94.213  1.00 79.18  ? 76  LEU D N   1 
ATOM 5861 C CA  . LEU D 1 76  ? 303.383 263.366 94.150  1.00 79.18  ? 76  LEU D CA  1 
ATOM 5862 C C   . LEU D 1 76  ? 304.244 263.535 95.396  1.00 79.18  ? 76  LEU D C   1 
ATOM 5863 O O   . LEU D 1 76  ? 303.722 263.641 96.511  1.00 79.18  ? 76  LEU D O   1 
ATOM 5864 C CB  . LEU D 1 76  ? 302.421 264.545 94.012  1.00 79.18  ? 76  LEU D CB  1 
ATOM 5865 C CG  . LEU D 1 76  ? 301.889 264.932 92.628  1.00 79.18  ? 76  LEU D CG  1 
ATOM 5866 C CD1 . LEU D 1 76  ? 300.818 263.976 92.118  1.00 79.18  ? 76  LEU D CD1 1 
ATOM 5867 C CD2 . LEU D 1 76  ? 301.371 266.362 92.655  1.00 79.18  ? 76  LEU D CD2 1 
ATOM 5868 N N   . TYR D 1 77  ? 305.557 263.555 95.202  1.00 80.12  ? 77  TYR D N   1 
ATOM 5869 C CA  . TYR D 1 77  ? 306.536 263.763 96.255  1.00 80.12  ? 77  TYR D CA  1 
ATOM 5870 C C   . TYR D 1 77  ? 307.075 265.187 96.178  1.00 80.12  ? 77  TYR D C   1 
ATOM 5871 O O   . TYR D 1 77  ? 306.563 266.031 95.436  1.00 80.12  ? 77  TYR D O   1 
ATOM 5872 C CB  . TYR D 1 77  ? 307.661 262.734 96.144  1.00 80.12  ? 77  TYR D CB  1 
ATOM 5873 C CG  . TYR D 1 77  ? 307.215 261.307 96.339  1.00 80.12  ? 77  TYR D CG  1 
ATOM 5874 C CD1 . TYR D 1 77  ? 306.842 260.523 95.255  1.00 80.12  ? 77  TYR D CD1 1 
ATOM 5875 C CD2 . TYR D 1 77  ? 307.170 260.743 97.606  1.00 80.12  ? 77  TYR D CD2 1 
ATOM 5876 C CE1 . TYR D 1 77  ? 306.433 259.217 95.428  1.00 80.12  ? 77  TYR D CE1 1 
ATOM 5877 C CE2 . TYR D 1 77  ? 306.762 259.435 97.792  1.00 80.12  ? 77  TYR D CE2 1 
ATOM 5878 C CZ  . TYR D 1 77  ? 306.397 258.677 96.699  1.00 80.12  ? 77  TYR D CZ  1 
ATOM 5879 O OH  . TYR D 1 77  ? 305.989 257.375 96.878  1.00 80.12  ? 77  TYR D OH  1 
ATOM 5880 N N   . GLU D 1 78  ? 308.116 265.456 96.961  1.00 79.06  ? 78  GLU D N   1 
ATOM 5881 C CA  . GLU D 1 78  ? 308.837 266.718 96.917  1.00 79.06  ? 78  GLU D CA  1 
ATOM 5882 C C   . GLU D 1 78  ? 310.320 266.432 97.079  1.00 79.06  ? 78  GLU D C   1 
ATOM 5883 O O   . GLU D 1 78  ? 310.725 265.719 98.002  1.00 79.06  ? 78  GLU D O   1 
ATOM 5884 C CB  . GLU D 1 78  ? 308.364 267.673 98.018  1.00 79.06  ? 78  GLU D CB  1 
ATOM 5885 C CG  . GLU D 1 78  ? 308.612 269.158 97.759  1.00 79.06  ? 78  GLU D CG  1 
ATOM 5886 C CD  . GLU D 1 78  ? 307.902 269.683 96.524  1.00 79.06  ? 78  GLU D CD  1 
ATOM 5887 O OE1 . GLU D 1 78  ? 306.701 269.388 96.354  1.00 79.06  ? 78  GLU D OE1 1 
ATOM 5888 O OE2 . GLU D 1 78  ? 308.532 270.422 95.741  1.00 79.06  ? 78  GLU D OE2 1 
ATOM 5889 N N   . ALA D 1 79  ? 311.127 266.981 96.177  1.00 78.89  ? 79  ALA D N   1 
ATOM 5890 C CA  . ALA D 1 79  ? 312.572 266.805 96.202  1.00 78.89  ? 79  ALA D CA  1 
ATOM 5891 C C   . ALA D 1 79  ? 313.226 268.074 96.724  1.00 78.89  ? 79  ALA D C   1 
ATOM 5892 O O   . ALA D 1 79  ? 312.796 269.185 96.397  1.00 78.89  ? 79  ALA D O   1 
ATOM 5893 C CB  . ALA D 1 79  ? 313.112 266.472 94.809  1.00 78.89  ? 79  ALA D CB  1 
ATOM 5894 N N   . LYS D 1 80  ? 314.267 267.907 97.538  1.00 84.78  ? 80  LYS D N   1 
ATOM 5895 C CA  . LYS D 1 80  ? 314.972 269.055 98.102  1.00 84.78  ? 80  LYS D CA  1 
ATOM 5896 C C   . LYS D 1 80  ? 316.443 268.667 98.222  1.00 84.78  ? 80  LYS D C   1 
ATOM 5897 O O   . LYS D 1 80  ? 316.831 267.981 99.172  1.00 84.78  ? 80  LYS D O   1 
ATOM 5898 C CB  . LYS D 1 80  ? 314.374 269.448 99.444  1.00 84.78  ? 80  LYS D CB  1 
ATOM 5899 C CG  . LYS D 1 80  ? 315.005 270.677 100.080 1.00 84.78  ? 80  LYS D CG  1 
ATOM 5900 C CD  . LYS D 1 80  ? 314.592 270.867 101.539 1.00 84.78  ? 80  LYS D CD  1 
ATOM 5901 C CE  . LYS D 1 80  ? 313.108 270.613 101.815 1.00 84.78  ? 80  LYS D CE  1 
ATOM 5902 N NZ  . LYS D 1 80  ? 312.171 271.387 100.953 1.00 84.78  ? 80  LYS D NZ  1 
ATOM 5903 N N   . VAL D 1 81  ? 317.244 269.095 97.250  1.00 87.45  ? 81  VAL D N   1 
ATOM 5904 C CA  . VAL D 1 81  ? 318.649 268.717 97.141  1.00 87.45  ? 81  VAL D CA  1 
ATOM 5905 C C   . VAL D 1 81  ? 319.511 269.969 97.226  1.00 87.45  ? 81  VAL D C   1 
ATOM 5906 O O   . VAL D 1 81  ? 319.318 270.916 96.454  1.00 87.45  ? 81  VAL D O   1 
ATOM 5907 C CB  . VAL D 1 81  ? 318.930 267.952 95.834  1.00 87.45  ? 81  VAL D CB  1 
ATOM 5908 C CG1 . VAL D 1 81  ? 320.374 267.498 95.778  1.00 87.45  ? 81  VAL D CG1 1 
ATOM 5909 C CG2 . VAL D 1 81  ? 318.009 266.752 95.716  1.00 87.45  ? 81  VAL D CG2 1 
ATOM 5910 N N   . TRP D 1 82  ? 320.459 269.970 98.162  1.00 92.16  ? 82  TRP D N   1 
ATOM 5911 C CA  . TRP D 1 82  ? 321.462 271.027 98.241  1.00 92.16  ? 82  TRP D CA  1 
ATOM 5912 C C   . TRP D 1 82  ? 322.557 270.724 97.228  1.00 92.16  ? 82  TRP D C   1 
ATOM 5913 O O   . TRP D 1 82  ? 323.321 269.768 97.398  1.00 92.16  ? 82  TRP D O   1 
ATOM 5914 C CB  . TRP D 1 82  ? 322.035 271.128 99.652  1.00 92.16  ? 82  TRP D CB  1 
ATOM 5915 C CG  . TRP D 1 82  ? 323.073 272.206 99.806  1.00 92.16  ? 82  TRP D CG  1 
ATOM 5916 C CD1 . TRP D 1 82  ? 322.847 273.538 100.010 1.00 92.16  ? 82  TRP D CD1 1 
ATOM 5917 C CD2 . TRP D 1 82  ? 324.499 272.043 99.771  1.00 92.16  ? 82  TRP D CD2 1 
ATOM 5918 N NE1 . TRP D 1 82  ? 324.040 274.213 100.101 1.00 92.16  ? 82  TRP D NE1 1 
ATOM 5919 C CE2 . TRP D 1 82  ? 325.070 273.320 99.958  1.00 92.16  ? 82  TRP D CE2 1 
ATOM 5920 C CE3 . TRP D 1 82  ? 325.348 270.943 99.600  1.00 92.16  ? 82  TRP D CE3 1 
ATOM 5921 C CZ2 . TRP D 1 82  ? 326.451 273.526 99.978  1.00 92.16  ? 82  TRP D CZ2 1 
ATOM 5922 C CZ3 . TRP D 1 82  ? 326.720 271.151 99.619  1.00 92.16  ? 82  TRP D CZ3 1 
ATOM 5923 C CH2 . TRP D 1 82  ? 327.256 272.432 99.807  1.00 92.16  ? 82  TRP D CH2 1 
ATOM 5924 N N   . VAL D 1 83  ? 322.636 271.529 96.174  1.00 85.76  ? 83  VAL D N   1 
ATOM 5925 C CA  . VAL D 1 83  ? 323.616 271.305 95.120  1.00 85.76  ? 83  VAL D CA  1 
ATOM 5926 C C   . VAL D 1 83  ? 324.887 272.092 95.411  1.00 85.76  ? 83  VAL D C   1 
ATOM 5927 O O   . VAL D 1 83  ? 325.365 272.118 96.544  1.00 85.76  ? 83  VAL D O   1 
ATOM 5928 C CB  . VAL D 1 83  ? 323.049 271.678 93.739  1.00 85.76  ? 83  VAL D CB  1 
ATOM 5929 C CG1 . VAL D 1 83  ? 321.991 270.682 93.313  1.00 85.76  ? 83  VAL D CG1 1 
ATOM 5930 C CG2 . VAL D 1 83  ? 322.477 273.074 93.763  1.00 85.76  ? 83  VAL D CG2 1 
ATOM 5931 N N   . GLY D 1 89  ? 328.098 272.109 84.182  1.00 74.75  ? 89  GLY D N   1 
ATOM 5932 C CA  . GLY D 1 89  ? 329.450 272.367 84.641  1.00 74.75  ? 89  GLY D CA  1 
ATOM 5933 C C   . GLY D 1 89  ? 329.535 272.659 86.126  1.00 74.75  ? 89  GLY D C   1 
ATOM 5934 O O   . GLY D 1 89  ? 329.792 271.763 86.930  1.00 74.75  ? 89  GLY D O   1 
ATOM 5935 N N   . LEU D 1 90  ? 329.316 273.924 86.493  1.00 79.31  ? 90  LEU D N   1 
ATOM 5936 C CA  . LEU D 1 90  ? 329.361 274.312 87.898  1.00 79.31  ? 90  LEU D CA  1 
ATOM 5937 C C   . LEU D 1 90  ? 328.127 273.853 88.662  1.00 79.31  ? 90  LEU D C   1 
ATOM 5938 O O   . LEU D 1 90  ? 328.187 273.718 89.889  1.00 79.31  ? 90  LEU D O   1 
ATOM 5939 C CB  . LEU D 1 90  ? 329.519 275.832 88.037  1.00 79.31  ? 90  LEU D CB  1 
ATOM 5940 C CG  . LEU D 1 90  ? 328.325 276.778 87.844  1.00 79.31  ? 90  LEU D CG  1 
ATOM 5941 C CD1 . LEU D 1 90  ? 328.635 278.122 88.483  1.00 79.31  ? 90  LEU D CD1 1 
ATOM 5942 C CD2 . LEU D 1 90  ? 327.954 276.975 86.380  1.00 79.31  ? 90  LEU D CD2 1 
ATOM 5943 N N   . ASN D 1 91  ? 327.014 273.611 87.970  1.00 84.26  ? 91  ASN D N   1 
ATOM 5944 C CA  . ASN D 1 91  ? 325.797 273.127 88.604  1.00 84.26  ? 91  ASN D CA  1 
ATOM 5945 C C   . ASN D 1 91  ? 325.628 271.618 88.494  1.00 84.26  ? 91  ASN D C   1 
ATOM 5946 O O   . ASN D 1 91  ? 324.719 271.065 89.124  1.00 84.26  ? 91  ASN D O   1 
ATOM 5947 C CB  . ASN D 1 91  ? 324.571 273.825 88.006  1.00 84.26  ? 91  ASN D CB  1 
ATOM 5948 C CG  . ASN D 1 91  ? 324.096 274.992 88.850  1.00 84.26  ? 91  ASN D CG  1 
ATOM 5949 O OD1 . ASN D 1 91  ? 324.517 275.155 89.995  1.00 84.26  ? 91  ASN D OD1 1 
ATOM 5950 N ND2 . ASN D 1 91  ? 323.212 275.808 88.290  1.00 84.26  ? 91  ASN D ND2 1 
ATOM 5951 N N   . LYS D 1 92  ? 326.469 270.942 87.714  1.00 85.82  ? 92  LYS D N   1 
ATOM 5952 C CA  . LYS D 1 92  ? 326.427 269.487 87.630  1.00 85.82  ? 92  LYS D CA  1 
ATOM 5953 C C   . LYS D 1 92  ? 327.562 268.835 88.409  1.00 85.82  ? 92  LYS D C   1 
ATOM 5954 O O   . LYS D 1 92  ? 327.350 267.817 89.078  1.00 85.82  ? 92  LYS D O   1 
ATOM 5955 C CB  . LYS D 1 92  ? 326.476 269.040 86.166  1.00 85.82  ? 92  LYS D CB  1 
ATOM 5956 C CG  . LYS D 1 92  ? 325.111 268.797 85.535  1.00 85.82  ? 92  LYS D CG  1 
ATOM 5957 C CD  . LYS D 1 92  ? 324.211 267.960 86.433  1.00 85.82  ? 92  LYS D CD  1 
ATOM 5958 C CE  . LYS D 1 92  ? 322.790 267.917 85.899  1.00 85.82  ? 92  LYS D CE  1 
ATOM 5959 N NZ  . LYS D 1 92  ? 321.821 267.436 86.924  1.00 85.82  ? 92  LYS D NZ  1 
ATOM 5960 N N   . TYR D 1 93  ? 328.766 269.399 88.330  1.00 88.88  ? 93  TYR D N   1 
ATOM 5961 C CA  . TYR D 1 93  ? 329.930 268.858 89.034  1.00 88.88  ? 93  TYR D CA  1 
ATOM 5962 C C   . TYR D 1 93  ? 330.130 269.576 90.371  1.00 88.88  ? 93  TYR D C   1 
ATOM 5963 O O   . TYR D 1 93  ? 331.179 270.153 90.657  1.00 88.88  ? 93  TYR D O   1 
ATOM 5964 C CB  . TYR D 1 93  ? 331.174 268.968 88.159  1.00 88.88  ? 93  TYR D CB  1 
ATOM 5965 C CG  . TYR D 1 93  ? 331.292 267.919 87.072  1.00 88.88  ? 93  TYR D CG  1 
ATOM 5966 C CD1 . TYR D 1 93  ? 332.366 267.931 86.191  1.00 88.88  ? 93  TYR D CD1 1 
ATOM 5967 C CD2 . TYR D 1 93  ? 330.341 266.912 86.933  1.00 88.88  ? 93  TYR D CD2 1 
ATOM 5968 C CE1 . TYR D 1 93  ? 332.488 266.979 85.196  1.00 88.88  ? 93  TYR D CE1 1 
ATOM 5969 C CE2 . TYR D 1 93  ? 330.453 265.955 85.940  1.00 88.88  ? 93  TYR D CE2 1 
ATOM 5970 C CZ  . TYR D 1 93  ? 331.529 265.993 85.076  1.00 88.88  ? 93  TYR D CZ  1 
ATOM 5971 O OH  . TYR D 1 93  ? 331.646 265.043 84.088  1.00 88.88  ? 93  TYR D OH  1 
ATOM 5972 N N   . ASN D 1 94  ? 329.093 269.530 91.198  1.00 90.36  ? 94  ASN D N   1 
ATOM 5973 C CA  . ASN D 1 94  ? 329.118 270.130 92.524  1.00 90.36  ? 94  ASN D CA  1 
ATOM 5974 C C   . ASN D 1 94  ? 328.821 269.066 93.575  1.00 90.36  ? 94  ASN D C   1 
ATOM 5975 O O   . ASN D 1 94  ? 328.657 267.882 93.271  1.00 90.36  ? 94  ASN D O   1 
ATOM 5976 C CB  . ASN D 1 94  ? 328.125 271.292 92.628  1.00 90.36  ? 94  ASN D CB  1 
ATOM 5977 C CG  . ASN D 1 94  ? 326.788 270.984 91.978  1.00 90.36  ? 94  ASN D CG  1 
ATOM 5978 O OD1 . ASN D 1 94  ? 326.491 269.837 91.644  1.00 90.36  ? 94  ASN D OD1 1 
ATOM 5979 N ND2 . ASN D 1 94  ? 325.963 272.011 91.819  1.00 90.36  ? 94  ASN D ND2 1 
ATOM 5980 N N   . PHE D 1 95  ? 328.755 269.505 94.828  1.00 96.12  ? 95  PHE D N   1 
ATOM 5981 C CA  . PHE D 1 95  ? 328.447 268.610 95.937  1.00 96.12  ? 95  PHE D CA  1 
ATOM 5982 C C   . PHE D 1 95  ? 326.946 268.345 95.942  1.00 96.12  ? 95  PHE D C   1 
ATOM 5983 O O   . PHE D 1 95  ? 326.144 269.281 96.011  1.00 96.12  ? 95  PHE D O   1 
ATOM 5984 C CB  . PHE D 1 95  ? 328.915 269.211 97.265  1.00 96.12  ? 95  PHE D CB  1 
ATOM 5985 C CG  . PHE D 1 95  ? 330.392 269.013 97.552  1.00 96.12  ? 95  PHE D CG  1 
ATOM 5986 C CD1 . PHE D 1 95  ? 331.367 269.397 96.636  1.00 96.12  ? 95  PHE D CD1 1 
ATOM 5987 C CD2 . PHE D 1 95  ? 330.801 268.433 98.746  1.00 96.12  ? 95  PHE D CD2 1 
ATOM 5988 C CE1 . PHE D 1 95  ? 332.711 269.211 96.905  1.00 96.12  ? 95  PHE D CE1 1 
ATOM 5989 C CE2 . PHE D 1 95  ? 332.147 268.244 99.021  1.00 96.12  ? 95  PHE D CE2 1 
ATOM 5990 C CZ  . PHE D 1 95  ? 333.101 268.634 98.099  1.00 96.12  ? 95  PHE D CZ  1 
ATOM 5991 N N   . LYS D 1 96  ? 326.567 267.071 95.865  1.00 92.54  ? 96  LYS D N   1 
ATOM 5992 C CA  . LYS D 1 96  ? 325.210 266.666 95.511  1.00 92.54  ? 96  LYS D CA  1 
ATOM 5993 C C   . LYS D 1 96  ? 324.670 265.703 96.560  1.00 92.54  ? 96  LYS D C   1 
ATOM 5994 O O   . LYS D 1 96  ? 325.144 264.566 96.658  1.00 92.54  ? 96  LYS D O   1 
ATOM 5995 C CB  . LYS D 1 96  ? 325.214 266.008 94.130  1.00 92.54  ? 96  LYS D CB  1 
ATOM 5996 C CG  . LYS D 1 96  ? 323.863 265.855 93.474  1.00 92.54  ? 96  LYS D CG  1 
ATOM 5997 C CD  . LYS D 1 96  ? 323.463 267.098 92.712  1.00 92.54  ? 96  LYS D CD  1 
ATOM 5998 C CE  . LYS D 1 96  ? 321.978 267.086 92.425  1.00 92.54  ? 96  LYS D CE  1 
ATOM 5999 N NZ  . LYS D 1 96  ? 321.589 266.029 91.450  1.00 92.54  ? 96  LYS D NZ  1 
ATOM 6000 N N   . GLU D 1 97  ? 323.671 266.148 97.327  1.00 87.58  ? 97  GLU D N   1 
ATOM 6001 C CA  . GLU D 1 97  ? 323.014 265.276 98.296  1.00 87.58  ? 97  GLU D CA  1 
ATOM 6002 C C   . GLU D 1 97  ? 321.614 265.784 98.608  1.00 87.58  ? 97  GLU D C   1 
ATOM 6003 O O   . GLU D 1 97  ? 321.429 266.973 98.884  1.00 87.58  ? 97  GLU D O   1 
ATOM 6004 C CB  . GLU D 1 97  ? 323.827 265.161 99.599  1.00 87.58  ? 97  GLU D CB  1 
ATOM 6005 C CG  . GLU D 1 97  ? 323.202 264.293 100.723 1.00 87.58  ? 97  GLU D CG  1 
ATOM 6006 C CD  . GLU D 1 97  ? 322.891 262.825 100.369 1.00 87.58  ? 97  GLU D CD  1 
ATOM 6007 O OE1 . GLU D 1 97  ? 322.226 262.167 101.198 1.00 87.58  ? 97  GLU D OE1 1 
ATOM 6008 O OE2 . GLU D 1 97  ? 323.352 262.291 99.336  1.00 87.58  ? 97  GLU D OE2 1 
ATOM 6009 N N   . LEU D 1 98  ? 320.643 264.873 98.567  1.00 86.14  ? 98  LEU D N   1 
ATOM 6010 C CA  . LEU D 1 98  ? 319.279 265.140 99.002  1.00 86.14  ? 98  LEU D CA  1 
ATOM 6011 C C   . LEU D 1 98  ? 319.181 265.044 100.520 1.00 86.14  ? 98  LEU D C   1 
ATOM 6012 O O   . LEU D 1 98  ? 319.897 264.270 101.159 1.00 86.14  ? 98  LEU D O   1 
ATOM 6013 C CB  . LEU D 1 98  ? 318.315 264.142 98.344  1.00 86.14  ? 98  LEU D CB  1 
ATOM 6014 C CG  . LEU D 1 98  ? 316.792 264.253 98.490  1.00 86.14  ? 98  LEU D CG  1 
ATOM 6015 C CD1 . LEU D 1 98  ? 316.090 263.939 97.184  1.00 86.14  ? 98  LEU D CD1 1 
ATOM 6016 C CD2 . LEU D 1 98  ? 316.300 263.297 99.568  1.00 86.14  ? 98  LEU D CD2 1 
ATOM 6017 N N   . GLN D 1 99  ? 318.277 265.830 101.099 1.00 94.33  ? 99  GLN D N   1 
ATOM 6018 C CA  . GLN D 1 99  ? 318.060 265.765 102.541 1.00 94.33  ? 99  GLN D CA  1 
ATOM 6019 C C   . GLN D 1 99  ? 316.638 265.396 102.935 1.00 94.33  ? 99  GLN D C   1 
ATOM 6020 O O   . GLN D 1 99  ? 316.455 264.638 103.892 1.00 94.33  ? 99  GLN D O   1 
ATOM 6021 C CB  . GLN D 1 99  ? 318.438 267.093 103.221 1.00 94.33  ? 99  GLN D CB  1 
ATOM 6022 C CG  . GLN D 1 99  ? 319.772 267.712 102.836 1.00 94.33  ? 99  GLN D CG  1 
ATOM 6023 C CD  . GLN D 1 99  ? 319.658 268.661 101.657 1.00 94.33  ? 99  GLN D CD  1 
ATOM 6024 O OE1 . GLN D 1 99  ? 319.376 268.244 100.535 1.00 94.33  ? 99  GLN D OE1 1 
ATOM 6025 N NE2 . GLN D 1 99  ? 319.837 269.952 101.919 1.00 94.33  ? 99  GLN D NE2 1 
ATOM 6026 N N   . GLU D 1 100 ? 315.621 265.912 102.243 1.00 92.21  ? 100 GLU D N   1 
ATOM 6027 C CA  . GLU D 1 100 ? 314.232 265.589 102.553 1.00 92.21  ? 100 GLU D CA  1 
ATOM 6028 C C   . GLU D 1 100 ? 313.531 264.945 101.363 1.00 92.21  ? 100 GLU D C   1 
ATOM 6029 O O   . GLU D 1 100 ? 313.760 265.310 100.205 1.00 92.21  ? 100 GLU D O   1 
ATOM 6030 C CB  . GLU D 1 100 ? 313.424 266.827 102.996 1.00 92.21  ? 100 GLU D CB  1 
ATOM 6031 C CG  . GLU D 1 100 ? 313.689 267.297 104.419 1.00 92.21  ? 100 GLU D CG  1 
ATOM 6032 C CD  . GLU D 1 100 ? 314.864 268.239 104.531 1.00 92.21  ? 100 GLU D CD  1 
ATOM 6033 O OE1 . GLU D 1 100 ? 315.549 268.466 103.517 1.00 92.21  ? 100 GLU D OE1 1 
ATOM 6034 O OE2 . GLU D 1 100 ? 315.104 268.755 105.644 1.00 92.21  ? 100 GLU D OE2 1 
ATOM 6035 N N   . PHE D 1 101 ? 312.649 263.997 101.676 1.00 80.12  ? 101 PHE D N   1 
ATOM 6036 C CA  . PHE D 1 101 ? 311.836 263.279 100.694 1.00 80.12  ? 101 PHE D CA  1 
ATOM 6037 C C   . PHE D 1 101 ? 310.381 263.259 101.166 1.00 80.12  ? 101 PHE D C   1 
ATOM 6038 O O   . PHE D 1 101 ? 309.733 262.214 101.244 1.00 80.12  ? 101 PHE D O   1 
ATOM 6039 C CB  . PHE D 1 101 ? 312.391 261.871 100.462 1.00 80.12  ? 101 PHE D CB  1 
ATOM 6040 C CG  . PHE D 1 101 ? 311.786 261.161 99.276  1.00 80.12  ? 101 PHE D CG  1 
ATOM 6041 C CD1 . PHE D 1 101 ? 311.348 261.874 98.170  1.00 80.12  ? 101 PHE D CD1 1 
ATOM 6042 C CD2 . PHE D 1 101 ? 311.648 259.780 99.277  1.00 80.12  ? 101 PHE D CD2 1 
ATOM 6043 C CE1 . PHE D 1 101 ? 310.788 261.223 97.086  1.00 80.12  ? 101 PHE D CE1 1 
ATOM 6044 C CE2 . PHE D 1 101 ? 311.089 259.121 98.193  1.00 80.12  ? 101 PHE D CE2 1 
ATOM 6045 C CZ  . PHE D 1 101 ? 310.657 259.846 97.098  1.00 80.12  ? 101 PHE D CZ  1 
ATOM 6046 N N   . LYS D 1 102 ? 309.862 264.431 101.509 1.00 69.77  ? 102 LYS D N   1 
ATOM 6047 C CA  . LYS D 1 102 ? 308.520 264.532 102.071 1.00 69.77  ? 102 LYS D CA  1 
ATOM 6048 C C   . LYS D 1 102 ? 307.467 264.415 100.971 1.00 69.77  ? 102 LYS D C   1 
ATOM 6049 O O   . LYS D 1 102 ? 307.529 265.151 99.982  1.00 69.77  ? 102 LYS D O   1 
ATOM 6050 C CB  . LYS D 1 102 ? 308.359 265.854 102.812 1.00 69.77  ? 102 LYS D CB  1 
ATOM 6051 C CG  . LYS D 1 102 ? 309.525 266.194 103.726 1.00 69.77  ? 102 LYS D CG  1 
ATOM 6052 C CD  . LYS D 1 102 ? 309.531 267.669 104.106 1.00 69.77  ? 102 LYS D CD  1 
ATOM 6053 C CE  . LYS D 1 102 ? 308.544 267.962 105.226 1.00 69.77  ? 102 LYS D CE  1 
ATOM 6054 N NZ  . LYS D 1 102 ? 308.883 267.249 106.484 1.00 69.77  ? 102 LYS D NZ  1 
ATOM 6055 N N   . PRO D 1 103 ? 306.495 263.516 101.106 1.00 70.01  ? 103 PRO D N   1 
ATOM 6056 C CA  . PRO D 1 103 ? 305.433 263.400 100.106 1.00 70.01  ? 103 PRO D CA  1 
ATOM 6057 C C   . PRO D 1 103 ? 304.260 264.328 100.397 1.00 70.01  ? 103 PRO D C   1 
ATOM 6058 O O   . PRO D 1 103 ? 304.068 264.812 101.514 1.00 70.01  ? 103 PRO D O   1 
ATOM 6059 C CB  . PRO D 1 103 ? 305.007 261.934 100.238 1.00 70.01  ? 103 PRO D CB  1 
ATOM 6060 C CG  . PRO D 1 103 ? 305.194 261.648 101.682 1.00 70.01  ? 103 PRO D CG  1 
ATOM 6061 C CD  . PRO D 1 103 ? 306.385 262.466 102.136 1.00 70.01  ? 103 PRO D CD  1 
ATOM 6062 N N   . VAL D 1 104 ? 303.470 264.570 99.356  1.00 73.81  ? 104 VAL D N   1 
ATOM 6063 C CA  . VAL D 1 104 ? 302.332 265.481 99.417  1.00 73.81  ? 104 VAL D CA  1 
ATOM 6064 C C   . VAL D 1 104 ? 301.073 264.660 99.674  1.00 73.81  ? 104 VAL D C   1 
ATOM 6065 O O   . VAL D 1 104 ? 300.599 263.937 98.791  1.00 73.81  ? 104 VAL D O   1 
ATOM 6066 C CB  . VAL D 1 104 ? 302.209 266.308 98.131  1.00 73.81  ? 104 VAL D CB  1 
ATOM 6067 C CG1 . VAL D 1 104 ? 301.262 267.474 98.339  1.00 73.81  ? 104 VAL D CG1 1 
ATOM 6068 C CG2 . VAL D 1 104 ? 303.578 266.798 97.692  1.00 73.81  ? 104 VAL D CG2 1 
ATOM 6069 N N   . GLY D 1 105 ? 300.514 264.787 100.876 1.00 67.69  ? 105 GLY D N   1 
ATOM 6070 C CA  . GLY D 1 105 ? 299.313 264.064 101.249 1.00 67.69  ? 105 GLY D CA  1 
ATOM 6071 C C   . GLY D 1 105 ? 299.499 263.037 102.350 1.00 67.69  ? 105 GLY D C   1 
ATOM 6072 O O   . GLY D 1 105 ? 299.994 261.933 102.107 1.00 67.69  ? 105 GLY D O   1 
ATOM 6073 N N   . ASP D 1 106 ? 299.100 263.394 103.572 1.00 59.77  ? 106 ASP D N   1 
ATOM 6074 C CA  . ASP D 1 106 ? 299.118 262.471 104.700 1.00 59.77  ? 106 ASP D CA  1 
ATOM 6075 C C   . ASP D 1 106 ? 297.847 261.642 104.791 1.00 59.77  ? 106 ASP D C   1 
ATOM 6076 O O   . ASP D 1 106 ? 297.813 260.662 105.541 1.00 59.77  ? 106 ASP D O   1 
ATOM 6077 C CB  . ASP D 1 106 ? 299.322 263.237 106.019 1.00 59.77  ? 106 ASP D CB  1 
ATOM 6078 C CG  . ASP D 1 106 ? 299.879 262.359 107.132 1.00 59.77  ? 106 ASP D CG  1 
ATOM 6079 O OD1 . ASP D 1 106 ? 301.098 262.114 107.156 1.00 59.77  ? 106 ASP D OD1 1 
ATOM 6080 O OD2 . ASP D 1 106 ? 299.095 261.904 107.983 1.00 59.77  ? 106 ASP D OD2 1 
ATOM 6081 N N   . ALA D 1 107 ? 296.807 262.001 104.040 1.00 64.10  ? 107 ALA D N   1 
ATOM 6082 C CA  . ALA D 1 107 ? 295.536 261.283 104.074 1.00 64.10  ? 107 ALA D CA  1 
ATOM 6083 C C   . ALA D 1 107 ? 295.672 259.998 103.261 1.00 64.10  ? 107 ALA D C   1 
ATOM 6084 O O   . ALA D 1 107 ? 295.215 259.884 102.120 1.00 64.10  ? 107 ALA D O   1 
ATOM 6085 C CB  . ALA D 1 107 ? 294.415 262.164 103.549 1.00 64.10  ? 107 ALA D CB  1 
ATOM 6086 N N   . GLY D 1 108 ? 296.311 259.006 103.875 1.00 58.94  ? 108 GLY D N   1 
ATOM 6087 C CA  . GLY D 1 108 ? 296.539 257.730 103.231 1.00 58.94  ? 108 GLY D CA  1 
ATOM 6088 C C   . GLY D 1 108 ? 296.154 256.575 104.127 1.00 58.94  ? 108 GLY D C   1 
ATOM 6089 O O   . GLY D 1 108 ? 296.805 255.526 104.117 1.00 58.94  ? 108 GLY D O   1 
ATOM 6090 N N   . GLY D 1 109 ? 295.098 256.761 104.915 1.00 59.88  ? 109 GLY D N   1 
ATOM 6091 C CA  . GLY D 1 109 ? 294.671 255.722 105.828 1.00 59.88  ? 109 GLY D CA  1 
ATOM 6092 C C   . GLY D 1 109 ? 295.600 255.506 106.995 1.00 59.88  ? 109 GLY D C   1 
ATOM 6093 O O   . GLY D 1 109 ? 295.623 254.411 107.564 1.00 59.88  ? 109 GLY D O   1 
ATOM 6094 N N   . ARG D 1 110 ? 296.380 256.526 107.362 1.00 50.13  ? 110 ARG D N   1 
ATOM 6095 C CA  . ARG D 1 110 ? 297.310 256.423 108.476 1.00 50.13  ? 110 ARG D CA  1 
ATOM 6096 C C   . ARG D 1 110 ? 296.598 256.373 109.816 1.00 50.13  ? 110 ARG D C   1 
ATOM 6097 O O   . ARG D 1 110 ? 297.191 255.926 110.799 1.00 50.13  ? 110 ARG D O   1 
ATOM 6098 C CB  . ARG D 1 110 ? 298.296 257.585 108.424 1.00 50.13  ? 110 ARG D CB  1 
ATOM 6099 C CG  . ARG D 1 110 ? 298.940 257.737 107.056 1.00 50.13  ? 110 ARG D CG  1 
ATOM 6100 C CD  . ARG D 1 110 ? 300.032 258.784 107.069 1.00 50.13  ? 110 ARG D CD  1 
ATOM 6101 N NE  . ARG D 1 110 ? 301.149 258.446 106.191 1.00 50.13  ? 110 ARG D NE  1 
ATOM 6102 C CZ  . ARG D 1 110 ? 302.235 257.787 106.582 1.00 50.13  ? 110 ARG D CZ  1 
ATOM 6103 N NH1 . ARG D 1 110 ? 302.359 257.387 107.836 1.00 50.13  ? 110 ARG D NH1 1 
ATOM 6104 N NH2 . ARG D 1 110 ? 303.203 257.531 105.718 1.00 50.13  ? 110 ARG D NH2 1 
ATOM 6105 N N   . MET D 1 111 ? 295.353 256.831 109.874 1.00 31.62  ? 111 MET D N   1 
ATOM 6106 C CA  . MET D 1 111 ? 294.410 256.455 110.915 1.00 31.62  ? 111 MET D CA  1 
ATOM 6107 C C   . MET D 1 111 ? 293.196 255.851 110.231 1.00 31.62  ? 111 MET D C   1 
ATOM 6108 O O   . MET D 1 111 ? 292.607 256.477 109.345 1.00 31.62  ? 111 MET D O   1 
ATOM 6109 C CB  . MET D 1 111 ? 293.983 257.649 111.762 1.00 31.62  ? 111 MET D CB  1 
ATOM 6110 C CG  . MET D 1 111 ? 294.905 257.966 112.890 1.00 31.62  ? 111 MET D CG  1 
ATOM 6111 S SD  . MET D 1 111 ? 294.510 259.559 113.586 1.00 31.62  ? 111 MET D SD  1 
ATOM 6112 C CE  . MET D 1 111 ? 295.008 260.585 112.212 1.00 31.62  ? 111 MET D CE  1 
ATOM 6113 N N   . ASP D 1 112 ? 292.836 254.632 110.616 1.00 31.70  ? 112 ASP D N   1 
ATOM 6114 C CA  . ASP D 1 112 ? 291.614 254.030 110.097 1.00 31.70  ? 112 ASP D CA  1 
ATOM 6115 C C   . ASP D 1 112 ? 290.500 254.454 111.038 1.00 31.70  ? 112 ASP D C   1 
ATOM 6116 O O   . ASP D 1 112 ? 290.188 253.778 112.017 1.00 31.70  ? 112 ASP D O   1 
ATOM 6117 C CB  . ASP D 1 112 ? 291.736 252.518 109.993 1.00 31.70  ? 112 ASP D CB  1 
ATOM 6118 C CG  . ASP D 1 112 ? 290.443 251.860 109.548 1.00 31.70  ? 112 ASP D CG  1 
ATOM 6119 O OD1 . ASP D 1 112 ? 290.218 251.773 108.322 1.00 31.70  ? 112 ASP D OD1 1 
ATOM 6120 O OD2 . ASP D 1 112 ? 289.656 251.423 110.415 1.00 31.70  ? 112 ASP D OD2 1 
ATOM 6121 N N   . ILE D 1 113 ? 289.923 255.607 110.763 1.00 19.39  ? 113 ILE D N   1 
ATOM 6122 C CA  . ILE D 1 113 ? 288.801 256.113 111.534 1.00 19.39  ? 113 ILE D CA  1 
ATOM 6123 C C   . ILE D 1 113 ? 287.534 255.743 110.791 1.00 19.39  ? 113 ILE D C   1 
ATOM 6124 O O   . ILE D 1 113 ? 287.457 255.869 109.565 1.00 19.39  ? 113 ILE D O   1 
ATOM 6125 C CB  . ILE D 1 113 ? 288.902 257.633 111.759 1.00 19.39  ? 113 ILE D CB  1 
ATOM 6126 C CG1 . ILE D 1 113 ? 290.244 257.996 112.384 1.00 19.39  ? 113 ILE D CG1 1 
ATOM 6127 C CG2 . ILE D 1 113 ? 287.822 258.110 112.684 1.00 19.39  ? 113 ILE D CG2 1 
ATOM 6128 C CD1 . ILE D 1 113 ? 290.431 259.465 112.615 1.00 19.39  ? 113 ILE D CD1 1 
ATOM 6129 N N   . ASP D 1 114 ? 286.585 255.259 111.507 1.00 12.79  ? 114 ASP D N   1 
ATOM 6130 C CA  . ASP D 1 114 ? 285.266 254.957 110.999 1.00 12.79  ? 114 ASP D CA  1 
ATOM 6131 C C   . ASP D 1 114 ? 284.329 256.077 111.399 1.00 12.79  ? 114 ASP D C   1 
ATOM 6132 O O   . ASP D 1 114 ? 284.336 256.479 112.571 1.00 12.79  ? 114 ASP D O   1 
ATOM 6133 C CB  . ASP D 1 114 ? 284.783 253.638 111.580 1.00 12.79  ? 114 ASP D CB  1 
ATOM 6134 C CG  . ASP D 1 114 ? 283.648 253.036 110.815 1.00 12.79  ? 114 ASP D CG  1 
ATOM 6135 O OD1 . ASP D 1 114 ? 283.911 252.107 110.036 1.00 12.79  ? 114 ASP D OD1 1 
ATOM 6136 O OD2 . ASP D 1 114 ? 282.501 253.471 111.002 1.00 12.79  ? 114 ASP D OD2 1 
ATOM 6137 N N   . PRO D 1 115 ? 283.548 256.636 110.469 1.00 11.69  ? 115 PRO D N   1 
ATOM 6138 C CA  . PRO D 1 115 ? 282.610 257.699 110.844 1.00 11.69  ? 115 PRO D CA  1 
ATOM 6139 C C   . PRO D 1 115 ? 281.524 257.231 111.773 1.00 11.69  ? 115 PRO D C   1 
ATOM 6140 O O   . PRO D 1 115 ? 280.977 258.048 112.521 1.00 11.69  ? 115 PRO D O   1 
ATOM 6141 C CB  . PRO D 1 115 ? 282.026 258.140 109.501 1.00 11.69  ? 115 PRO D CB  1 
ATOM 6142 C CG  . PRO D 1 115 ? 282.978 257.693 108.498 1.00 11.69  ? 115 PRO D CG  1 
ATOM 6143 C CD  . PRO D 1 115 ? 283.600 256.447 109.013 1.00 11.69  ? 115 PRO D CD  1 
ATOM 6144 N N   . TYR D 1 116 ? 281.214 255.936 111.770 1.00 11.02  ? 116 TYR D N   1 
ATOM 6145 C CA  . TYR D 1 116 ? 280.118 255.398 112.555 1.00 11.02  ? 116 TYR D CA  1 
ATOM 6146 C C   . TYR D 1 116 ? 280.601 254.368 113.562 1.00 11.02  ? 116 TYR D C   1 
ATOM 6147 O O   . TYR D 1 116 ? 279.822 253.507 113.938 1.00 11.02  ? 116 TYR D O   1 
ATOM 6148 C CB  . TYR D 1 116 ? 279.088 254.727 111.651 1.00 11.02  ? 116 TYR D CB  1 
ATOM 6149 C CG  . TYR D 1 116 ? 278.818 255.399 110.338 1.00 11.02  ? 116 TYR D CG  1 
ATOM 6150 C CD1 . TYR D 1 116 ? 277.993 256.499 110.230 1.00 11.02  ? 116 TYR D CD1 1 
ATOM 6151 C CD2 . TYR D 1 116 ? 279.368 254.885 109.191 1.00 11.02  ? 116 TYR D CD2 1 
ATOM 6152 C CE1 . TYR D 1 116 ? 277.774 257.080 109.010 1.00 11.02  ? 116 TYR D CE1 1 
ATOM 6153 C CE2 . TYR D 1 116 ? 279.146 255.444 107.989 1.00 11.02  ? 116 TYR D CE2 1 
ATOM 6154 C CZ  . TYR D 1 116 ? 278.349 256.525 107.893 1.00 11.02  ? 116 TYR D CZ  1 
ATOM 6155 O OH  . TYR D 1 116 ? 278.167 257.052 106.645 1.00 11.02  ? 116 TYR D OH  1 
ATOM 6156 N N   . LYS D 1 117 ? 281.857 254.405 114.005 1.00 11.89  ? 117 LYS D N   1 
ATOM 6157 C CA  . LYS D 1 117 ? 282.306 253.407 114.977 1.00 11.89  ? 117 LYS D CA  1 
ATOM 6158 C C   . LYS D 1 117 ? 281.754 253.714 116.356 1.00 11.89  ? 117 LYS D C   1 
ATOM 6159 O O   . LYS D 1 117 ? 281.271 252.824 117.062 1.00 11.89  ? 117 LYS D O   1 
ATOM 6160 C CB  . LYS D 1 117 ? 283.824 253.340 115.024 1.00 11.89  ? 117 LYS D CB  1 
ATOM 6161 C CG  . LYS D 1 117 ? 284.358 252.318 115.995 1.00 11.89  ? 117 LYS D CG  1 
ATOM 6162 C CD  . LYS D 1 117 ? 284.268 250.927 115.428 1.00 11.89  ? 117 LYS D CD  1 
ATOM 6163 C CE  . LYS D 1 117 ? 285.326 250.691 114.369 1.00 11.89  ? 117 LYS D CE  1 
ATOM 6164 N NZ  . LYS D 1 117 ? 286.697 250.721 114.939 1.00 11.89  ? 117 LYS D NZ  1 
ATOM 6165 N N   . GLU D 1 118 ? 281.797 254.982 116.744 1.00 12.76  ? 118 GLU D N   1 
ATOM 6166 C CA  . GLU D 1 118 ? 280.895 255.514 117.747 1.00 12.76  ? 118 GLU D CA  1 
ATOM 6167 C C   . GLU D 1 118 ? 279.457 255.442 117.229 1.00 12.76  ? 118 GLU D C   1 
ATOM 6168 O O   . GLU D 1 118 ? 279.211 255.144 116.068 1.00 12.76  ? 118 GLU D O   1 
ATOM 6169 C CB  . GLU D 1 118 ? 281.288 256.949 118.060 1.00 12.76  ? 118 GLU D CB  1 
ATOM 6170 C CG  . GLU D 1 118 ? 281.859 257.636 116.833 1.00 12.76  ? 118 GLU D CG  1 
ATOM 6171 C CD  . GLU D 1 118 ? 282.107 259.107 117.027 1.00 12.76  ? 118 GLU D CD  1 
ATOM 6172 O OE1 . GLU D 1 118 ? 281.941 259.601 118.155 1.00 12.76  ? 118 GLU D OE1 1 
ATOM 6173 O OE2 . GLU D 1 118 ? 282.446 259.781 116.037 1.00 12.76  ? 118 GLU D OE2 1 
ATOM 6174 N N   . PHE D 1 119 ? 278.491 255.684 118.114 1.00 11.73  ? 119 PHE D N   1 
ATOM 6175 C CA  . PHE D 1 119 ? 277.045 255.603 117.855 1.00 11.73  ? 119 PHE D CA  1 
ATOM 6176 C C   . PHE D 1 119 ? 276.547 254.182 117.567 1.00 11.73  ? 119 PHE D C   1 
ATOM 6177 O O   . PHE D 1 119 ? 275.339 253.982 117.440 1.00 11.73  ? 119 PHE D O   1 
ATOM 6178 C CB  . PHE D 1 119 ? 276.528 256.488 116.691 1.00 11.73  ? 119 PHE D CB  1 
ATOM 6179 C CG  . PHE D 1 119 ? 277.280 257.769 116.465 1.00 11.73  ? 119 PHE D CG  1 
ATOM 6180 C CD1 . PHE D 1 119 ? 277.124 258.836 117.312 1.00 11.73  ? 119 PHE D CD1 1 
ATOM 6181 C CD2 . PHE D 1 119 ? 278.061 257.929 115.340 1.00 11.73  ? 119 PHE D CD2 1 
ATOM 6182 C CE1 . PHE D 1 119 ? 277.794 260.002 117.087 1.00 11.73  ? 119 PHE D CE1 1 
ATOM 6183 C CE2 . PHE D 1 119 ? 278.733 259.091 115.112 1.00 11.73  ? 119 PHE D CE2 1 
ATOM 6184 C CZ  . PHE D 1 119 ? 278.587 260.131 115.982 1.00 11.73  ? 119 PHE D CZ  1 
ATOM 6185 N N   . GLY D 1 120 ? 277.422 253.182 117.455 1.00 9.48   ? 120 GLY D N   1 
ATOM 6186 C CA  . GLY D 1 120 ? 277.017 251.797 117.399 1.00 9.48   ? 120 GLY D CA  1 
ATOM 6187 C C   . GLY D 1 120 ? 277.230 251.114 116.062 1.00 9.48   ? 120 GLY D C   1 
ATOM 6188 O O   . GLY D 1 120 ? 277.405 249.894 116.031 1.00 9.48   ? 120 GLY D O   1 
ATOM 6189 N N   . ALA D 1 121 ? 277.210 251.855 114.963 1.00 8.34   ? 121 ALA D N   1 
ATOM 6190 C CA  . ALA D 1 121 ? 277.176 251.225 113.649 1.00 8.34   ? 121 ALA D CA  1 
ATOM 6191 C C   . ALA D 1 121 ? 278.571 250.785 113.213 1.00 8.34   ? 121 ALA D C   1 
ATOM 6192 O O   . ALA D 1 121 ? 279.501 250.690 114.013 1.00 8.34   ? 121 ALA D O   1 
ATOM 6193 C CB  . ALA D 1 121 ? 276.555 252.167 112.630 1.00 8.34   ? 121 ALA D CB  1 
ATOM 6194 N N   . THR D 1 122 ? 278.709 250.415 111.941 1.00 10.24  ? 122 THR D N   1 
ATOM 6195 C CA  . THR D 1 122 ? 279.989 250.359 111.246 1.00 10.24  ? 122 THR D CA  1 
ATOM 6196 C C   . THR D 1 122 ? 279.766 250.945 109.864 1.00 10.24  ? 122 THR D C   1 
ATOM 6197 O O   . THR D 1 122 ? 278.682 251.426 109.547 1.00 10.24  ? 122 THR D O   1 
ATOM 6198 C CB  . THR D 1 122 ? 280.562 248.946 111.061 1.00 10.24  ? 122 THR D CB  1 
ATOM 6199 O OG1 . THR D 1 122 ? 280.007 248.377 109.872 1.00 10.24  ? 122 THR D OG1 1 
ATOM 6200 C CG2 . THR D 1 122 ? 280.292 248.005 112.236 1.00 10.24  ? 122 THR D CG2 1 
ATOM 6201 N N   . VAL D 1 123 ? 280.788 250.882 109.018 1.00 7.16   ? 123 VAL D N   1 
ATOM 6202 C CA  . VAL D 1 123 ? 280.593 251.241 107.618 1.00 7.16   ? 123 VAL D CA  1 
ATOM 6203 C C   . VAL D 1 123 ? 279.867 250.134 106.884 1.00 7.16   ? 123 VAL D C   1 
ATOM 6204 O O   . VAL D 1 123 ? 278.924 250.391 106.131 1.00 7.16   ? 123 VAL D O   1 
ATOM 6205 C CB  . VAL D 1 123 ? 281.940 251.583 106.956 1.00 7.16   ? 123 VAL D CB  1 
ATOM 6206 C CG1 . VAL D 1 123 ? 281.851 251.519 105.449 1.00 7.16   ? 123 VAL D CG1 1 
ATOM 6207 C CG2 . VAL D 1 123 ? 282.339 252.978 107.339 1.00 7.16   ? 123 VAL D CG2 1 
ATOM 6208 N N   . GLU D 1 124 ? 280.255 248.885 107.115 1.00 15.94  ? 124 GLU D N   1 
ATOM 6209 C CA  . GLU D 1 124 ? 279.642 247.787 106.386 1.00 15.94  ? 124 GLU D CA  1 
ATOM 6210 C C   . GLU D 1 124 ? 278.272 247.412 106.922 1.00 15.94  ? 124 GLU D C   1 
ATOM 6211 O O   . GLU D 1 124 ? 277.558 246.660 106.258 1.00 15.94  ? 124 GLU D O   1 
ATOM 6212 C CB  . GLU D 1 124 ? 280.562 246.570 106.387 1.00 15.94  ? 124 GLU D CB  1 
ATOM 6213 C CG  . GLU D 1 124 ? 281.335 246.354 107.664 1.00 15.94  ? 124 GLU D CG  1 
ATOM 6214 C CD  . GLU D 1 124 ? 282.292 245.186 107.564 1.00 15.94  ? 124 GLU D CD  1 
ATOM 6215 O OE1 . GLU D 1 124 ? 282.219 244.439 106.567 1.00 15.94  ? 124 GLU D OE1 1 
ATOM 6216 O OE2 . GLU D 1 124 ? 283.122 245.012 108.478 1.00 15.94  ? 124 GLU D OE2 1 
ATOM 6217 N N   . LEU D 1 125 ? 277.888 247.914 108.093 1.00 9.11   ? 125 LEU D N   1 
ATOM 6218 C CA  . LEU D 1 125 ? 276.487 247.863 108.484 1.00 9.11   ? 125 LEU D CA  1 
ATOM 6219 C C   . LEU D 1 125 ? 275.667 248.848 107.672 1.00 9.11   ? 125 LEU D C   1 
ATOM 6220 O O   . LEU D 1 125 ? 274.495 248.601 107.395 1.00 9.11   ? 125 LEU D O   1 
ATOM 6221 C CB  . LEU D 1 125 ? 276.355 248.144 109.975 1.00 9.11   ? 125 LEU D CB  1 
ATOM 6222 C CG  . LEU D 1 125 ? 274.971 248.145 110.603 1.00 9.11   ? 125 LEU D CG  1 
ATOM 6223 C CD1 . LEU D 1 125 ? 274.278 246.867 110.288 1.00 9.11   ? 125 LEU D CD1 1 
ATOM 6224 C CD2 . LEU D 1 125 ? 275.068 248.296 112.090 1.00 9.11   ? 125 LEU D CD2 1 
ATOM 6225 N N   . LEU D 1 126 ? 276.272 249.946 107.252 1.00 12.61  ? 126 LEU D N   1 
ATOM 6226 C CA  . LEU D 1 126 ? 275.625 250.929 106.400 1.00 12.61  ? 126 LEU D CA  1 
ATOM 6227 C C   . LEU D 1 126 ? 275.740 250.583 104.930 1.00 12.61  ? 126 LEU D C   1 
ATOM 6228 O O   . LEU D 1 126 ? 275.400 251.411 104.084 1.00 12.61  ? 126 LEU D O   1 
ATOM 6229 C CB  . LEU D 1 126 ? 276.219 252.315 106.643 1.00 12.61  ? 126 LEU D CB  1 
ATOM 6230 C CG  . LEU D 1 126 ? 275.587 253.300 107.619 1.00 12.61  ? 126 LEU D CG  1 
ATOM 6231 C CD1 . LEU D 1 126 ? 274.322 253.815 107.041 1.00 12.61  ? 126 LEU D CD1 1 
ATOM 6232 C CD2 . LEU D 1 126 ? 275.327 252.669 108.954 1.00 12.61  ? 126 LEU D CD2 1 
ATOM 6233 N N   . SER D 1 127 ? 276.238 249.397 104.604 1.00 12.29  ? 127 SER D N   1 
ATOM 6234 C CA  . SER D 1 127 ? 276.186 248.885 103.247 1.00 12.29  ? 127 SER D CA  1 
ATOM 6235 C C   . SER D 1 127 ? 275.084 247.858 103.087 1.00 12.29  ? 127 SER D C   1 
ATOM 6236 O O   . SER D 1 127 ? 274.990 247.214 102.039 1.00 12.29  ? 127 SER D O   1 
ATOM 6237 C CB  . SER D 1 127 ? 277.528 248.289 102.844 1.00 12.29  ? 127 SER D CB  1 
ATOM 6238 O OG  . SER D 1 127 ? 278.411 249.306 102.417 1.00 12.29  ? 127 SER D OG  1 
ATOM 6239 N N   . PHE D 1 128 ? 274.259 247.679 104.119 1.00 10.42  ? 128 PHE D N   1 
ATOM 6240 C CA  . PHE D 1 128 ? 273.054 246.878 103.972 1.00 10.42  ? 128 PHE D CA  1 
ATOM 6241 C C   . PHE D 1 128 ? 272.059 247.586 103.074 1.00 10.42  ? 128 PHE D C   1 
ATOM 6242 O O   . PHE D 1 128 ? 271.465 246.968 102.187 1.00 10.42  ? 128 PHE D O   1 
ATOM 6243 C CB  . PHE D 1 128 ? 272.436 246.602 105.337 1.00 10.42  ? 128 PHE D CB  1 
ATOM 6244 C CG  . PHE D 1 128 ? 273.126 245.528 106.120 1.00 10.42  ? 128 PHE D CG  1 
ATOM 6245 C CD1 . PHE D 1 128 ? 274.214 244.858 105.610 1.00 10.42  ? 128 PHE D CD1 1 
ATOM 6246 C CD2 . PHE D 1 128 ? 272.680 245.190 107.376 1.00 10.42  ? 128 PHE D CD2 1 
ATOM 6247 C CE1 . PHE D 1 128 ? 274.837 243.887 106.331 1.00 10.42  ? 128 PHE D CE1 1 
ATOM 6248 C CE2 . PHE D 1 128 ? 273.304 244.209 108.098 1.00 10.42  ? 128 PHE D CE2 1 
ATOM 6249 C CZ  . PHE D 1 128 ? 274.377 243.566 107.578 1.00 10.42  ? 128 PHE D CZ  1 
ATOM 6250 N N   . LEU D 1 129 ? 271.877 248.882 103.291 1.00 14.94  ? 129 LEU D N   1 
ATOM 6251 C CA  . LEU D 1 129 ? 271.128 249.719 102.375 1.00 14.94  ? 129 LEU D CA  1 
ATOM 6252 C C   . LEU D 1 129 ? 271.875 249.813 101.049 1.00 14.94  ? 129 LEU D C   1 
ATOM 6253 O O   . LEU D 1 129 ? 273.103 249.893 101.040 1.00 14.94  ? 129 LEU D O   1 
ATOM 6254 C CB  . LEU D 1 129 ? 270.969 251.110 102.968 1.00 14.94  ? 129 LEU D CB  1 
ATOM 6255 C CG  . LEU D 1 129 ? 270.736 251.167 104.474 1.00 14.94  ? 129 LEU D CG  1 
ATOM 6256 C CD1 . LEU D 1 129 ? 270.894 252.554 104.973 1.00 14.94  ? 129 LEU D CD1 1 
ATOM 6257 C CD2 . LEU D 1 129 ? 269.382 250.682 104.855 1.00 14.94  ? 129 LEU D CD2 1 
ATOM 6258 N N   . PRO D 1 130 ? 271.179 249.801 99.921  1.00 14.84  ? 130 PRO D N   1 
ATOM 6259 C CA  . PRO D 1 130 ? 271.868 249.966 98.637  1.00 14.84  ? 130 PRO D CA  1 
ATOM 6260 C C   . PRO D 1 130 ? 272.372 251.380 98.423  1.00 14.84  ? 130 PRO D C   1 
ATOM 6261 O O   . PRO D 1 130 ? 272.148 252.252 99.264  1.00 14.84  ? 130 PRO D O   1 
ATOM 6262 C CB  . PRO D 1 130 ? 270.794 249.591 97.613  1.00 14.84  ? 130 PRO D CB  1 
ATOM 6263 C CG  . PRO D 1 130 ? 269.540 249.732 98.316  1.00 14.84  ? 130 PRO D CG  1 
ATOM 6264 C CD  . PRO D 1 130 ? 269.787 249.388 99.730  1.00 14.84  ? 130 PRO D CD  1 
ATOM 6265 N N   . SER D 1 131 ? 273.059 251.621 97.308  1.00 24.63  ? 131 SER D N   1 
ATOM 6266 C CA  . SER D 1 131 ? 273.663 252.930 97.086  1.00 24.63  ? 131 SER D CA  1 
ATOM 6267 C C   . SER D 1 131 ? 272.609 253.990 96.816  1.00 24.63  ? 131 SER D C   1 
ATOM 6268 O O   . SER D 1 131 ? 272.640 255.071 97.411  1.00 24.63  ? 131 SER D O   1 
ATOM 6269 C CB  . SER D 1 131 ? 274.654 252.874 95.930  1.00 24.63  ? 131 SER D CB  1 
ATOM 6270 O OG  . SER D 1 131 ? 274.817 254.164 95.369  1.00 24.63  ? 131 SER D OG  1 
ATOM 6271 N N   . ASP D 1 132 ? 271.669 253.706 95.922  1.00 21.28  ? 132 ASP D N   1 
ATOM 6272 C CA  . ASP D 1 132 ? 270.623 254.676 95.616  1.00 21.28  ? 132 ASP D CA  1 
ATOM 6273 C C   . ASP D 1 132 ? 269.376 254.465 96.464  1.00 21.28  ? 132 ASP D C   1 
ATOM 6274 O O   . ASP D 1 132 ? 268.251 254.522 95.989  1.00 21.28  ? 132 ASP D O   1 
ATOM 6275 C CB  . ASP D 1 132 ? 270.297 254.613 94.133  1.00 21.28  ? 132 ASP D CB  1 
ATOM 6276 C CG  . ASP D 1 132 ? 269.851 253.241 93.697  1.00 21.28  ? 132 ASP D CG  1 
ATOM 6277 O OD1 . ASP D 1 132 ? 270.462 252.254 94.153  1.00 21.28  ? 132 ASP D OD1 1 
ATOM 6278 O OD2 . ASP D 1 132 ? 268.892 253.152 92.902  1.00 21.28  ? 132 ASP D OD2 1 
ATOM 6279 N N   . PHE D 1 133 ? 269.579 254.272 97.755  1.00 21.73  ? 133 PHE D N   1 
ATOM 6280 C CA  . PHE D 1 133 ? 268.502 254.251 98.723  1.00 21.73  ? 133 PHE D CA  1 
ATOM 6281 C C   . PHE D 1 133 ? 268.389 255.578 99.433  1.00 21.73  ? 133 PHE D C   1 
ATOM 6282 O O   . PHE D 1 133 ? 267.307 255.942 99.903  1.00 21.73  ? 133 PHE D O   1 
ATOM 6283 C CB  . PHE D 1 133 ? 268.751 253.129 99.734  1.00 21.73  ? 133 PHE D CB  1 
ATOM 6284 C CG  . PHE D 1 133 ? 267.954 253.232 100.988 1.00 21.73  ? 133 PHE D CG  1 
ATOM 6285 C CD1 . PHE D 1 133 ? 266.643 252.844 101.008 1.00 21.73  ? 133 PHE D CD1 1 
ATOM 6286 C CD2 . PHE D 1 133 ? 268.527 253.690 102.156 1.00 21.73  ? 133 PHE D CD2 1 
ATOM 6287 C CE1 . PHE D 1 133 ? 265.914 252.933 102.160 1.00 21.73  ? 133 PHE D CE1 1 
ATOM 6288 C CE2 . PHE D 1 133 ? 267.803 253.783 103.301 1.00 21.73  ? 133 PHE D CE2 1 
ATOM 6289 C CZ  . PHE D 1 133 ? 266.497 253.404 103.305 1.00 21.73  ? 133 PHE D CZ  1 
ATOM 6290 N N   . PHE D 1 134 ? 269.455 256.300 99.481  1.00 28.56  ? 134 PHE D N   1 
ATOM 6291 C CA  . PHE D 1 134 ? 269.545 257.500 100.270 1.00 28.56  ? 134 PHE D CA  1 
ATOM 6292 C C   . PHE D 1 134 ? 268.907 258.662 99.528  1.00 28.56  ? 134 PHE D C   1 
ATOM 6293 O O   . PHE D 1 134 ? 268.934 258.710 98.298  1.00 28.56  ? 134 PHE D O   1 
ATOM 6294 C CB  . PHE D 1 134 ? 270.999 257.791 100.582 1.00 28.56  ? 134 PHE D CB  1 
ATOM 6295 C CG  . PHE D 1 134 ? 271.651 256.708 101.354 1.00 28.56  ? 134 PHE D CG  1 
ATOM 6296 C CD1 . PHE D 1 134 ? 271.442 256.599 102.705 1.00 28.56  ? 134 PHE D CD1 1 
ATOM 6297 C CD2 . PHE D 1 134 ? 272.446 255.780 100.728 1.00 28.56  ? 134 PHE D CD2 1 
ATOM 6298 C CE1 . PHE D 1 134 ? 272.018 255.599 103.418 1.00 28.56  ? 134 PHE D CE1 1 
ATOM 6299 C CE2 . PHE D 1 134 ? 273.018 254.775 101.443 1.00 28.56  ? 134 PHE D CE2 1 
ATOM 6300 C CZ  . PHE D 1 134 ? 272.807 254.693 102.791 1.00 28.56  ? 134 PHE D CZ  1 
ATOM 6301 N N   . PRO D 1 135 ? 268.314 259.600 100.254 1.00 18.61  ? 135 PRO D N   1 
ATOM 6302 C CA  . PRO D 1 135 ? 267.734 260.783 99.614  1.00 18.61  ? 135 PRO D CA  1 
ATOM 6303 C C   . PRO D 1 135 ? 268.775 261.683 98.982  1.00 18.61  ? 135 PRO D C   1 
ATOM 6304 O O   . PRO D 1 135 ? 269.972 261.414 99.069  1.00 18.61  ? 135 PRO D O   1 
ATOM 6305 C CB  . PRO D 1 135 ? 267.038 261.490 100.775 1.00 18.61  ? 135 PRO D CB  1 
ATOM 6306 C CG  . PRO D 1 135 ? 266.834 260.446 101.786 1.00 18.61  ? 135 PRO D CG  1 
ATOM 6307 C CD  . PRO D 1 135 ? 267.967 259.529 101.680 1.00 18.61  ? 135 PRO D CD  1 
ATOM 6308 N N   . SER D 1 136 ? 268.351 262.768 98.354  1.00 27.47  ? 136 SER D N   1 
ATOM 6309 C CA  . SER D 1 136 ? 269.330 263.694 97.822  1.00 27.47  ? 136 SER D CA  1 
ATOM 6310 C C   . SER D 1 136 ? 269.976 264.484 98.953  1.00 27.47  ? 136 SER D C   1 
ATOM 6311 O O   . SER D 1 136 ? 269.594 264.387 100.121 1.00 27.47  ? 136 SER D O   1 
ATOM 6312 C CB  . SER D 1 136 ? 268.686 264.644 96.824  1.00 27.47  ? 136 SER D CB  1 
ATOM 6313 O OG  . SER D 1 136 ? 269.624 265.612 96.404  1.00 27.47  ? 136 SER D OG  1 
ATOM 6314 N N   . VAL D 1 137 ? 270.989 265.268 98.603  1.00 23.41  ? 137 VAL D N   1 
ATOM 6315 C CA  . VAL D 1 137 ? 271.584 266.106 99.630  1.00 23.41  ? 137 VAL D CA  1 
ATOM 6316 C C   . VAL D 1 137 ? 270.658 267.268 99.950  1.00 23.41  ? 137 VAL D C   1 
ATOM 6317 O O   . VAL D 1 137 ? 270.608 267.728 101.096 1.00 23.41  ? 137 VAL D O   1 
ATOM 6318 C CB  . VAL D 1 137 ? 272.968 266.590 99.189  1.00 23.41  ? 137 VAL D CB  1 
ATOM 6319 C CG1 . VAL D 1 137 ? 273.758 267.022 100.391 1.00 23.41  ? 137 VAL D CG1 1 
ATOM 6320 C CG2 . VAL D 1 137 ? 273.685 265.504 98.441  1.00 23.41  ? 137 VAL D CG2 1 
ATOM 6321 N N   . ARG D 1 138 ? 269.876 267.718 98.965  1.00 35.98  ? 138 ARG D N   1 
ATOM 6322 C CA  . ARG D 1 138 ? 268.922 268.795 99.194  1.00 35.98  ? 138 ARG D CA  1 
ATOM 6323 C C   . ARG D 1 138 ? 267.795 268.352 100.110 1.00 35.98  ? 138 ARG D C   1 
ATOM 6324 O O   . ARG D 1 138 ? 267.383 269.107 100.991 1.00 35.98  ? 138 ARG D O   1 
ATOM 6325 C CB  . ARG D 1 138 ? 268.355 269.287 97.870  1.00 35.98  ? 138 ARG D CB  1 
ATOM 6326 C CG  . ARG D 1 138 ? 269.383 269.460 96.787  1.00 35.98  ? 138 ARG D CG  1 
ATOM 6327 C CD  . ARG D 1 138 ? 268.920 270.486 95.764  1.00 35.98  ? 138 ARG D CD  1 
ATOM 6328 N NE  . ARG D 1 138 ? 268.798 271.816 96.354  1.00 35.98  ? 138 ARG D NE  1 
ATOM 6329 C CZ  . ARG D 1 138 ? 269.470 272.885 95.942  1.00 35.98  ? 138 ARG D CZ  1 
ATOM 6330 N NH1 . ARG D 1 138 ? 269.296 274.052 96.546  1.00 35.98  ? 138 ARG D NH1 1 
ATOM 6331 N NH2 . ARG D 1 138 ? 270.315 272.790 94.928  1.00 35.98  ? 138 ARG D NH2 1 
ATOM 6332 N N   . ASP D 1 139 ? 267.306 267.123 99.942  1.00 26.31  ? 139 ASP D N   1 
ATOM 6333 C CA  . ASP D 1 139 ? 266.201 266.646 100.765 1.00 26.31  ? 139 ASP D CA  1 
ATOM 6334 C C   . ASP D 1 139 ? 266.643 266.394 102.194 1.00 26.31  ? 139 ASP D C   1 
ATOM 6335 O O   . ASP D 1 139 ? 265.916 266.705 103.143 1.00 26.31  ? 139 ASP D O   1 
ATOM 6336 C CB  . ASP D 1 139 ? 265.617 265.378 100.162 1.00 26.31  ? 139 ASP D CB  1 
ATOM 6337 C CG  . ASP D 1 139 ? 265.185 265.565 98.729  1.00 26.31  ? 139 ASP D CG  1 
ATOM 6338 O OD1 . ASP D 1 139 ? 264.871 264.558 98.064  1.00 26.31  ? 139 ASP D OD1 1 
ATOM 6339 O OD2 . ASP D 1 139 ? 265.160 266.720 98.263  1.00 26.31  ? 139 ASP D OD2 1 
ATOM 6340 N N   . LEU D 1 140 ? 267.854 265.878 102.371 1.00 18.30  ? 140 LEU D N   1 
ATOM 6341 C CA  . LEU D 1 140 ? 268.371 265.672 103.714 1.00 18.30  ? 140 LEU D CA  1 
ATOM 6342 C C   . LEU D 1 140 ? 268.707 266.988 104.395 1.00 18.30  ? 140 LEU D C   1 
ATOM 6343 O O   . LEU D 1 140 ? 268.496 267.131 105.604 1.00 18.30  ? 140 LEU D O   1 
ATOM 6344 C CB  . LEU D 1 140 ? 269.593 264.772 103.659 1.00 18.30  ? 140 LEU D CB  1 
ATOM 6345 C CG  . LEU D 1 140 ? 269.254 263.340 103.299 1.00 18.30  ? 140 LEU D CG  1 
ATOM 6346 C CD1 . LEU D 1 140 ? 270.494 262.616 102.879 1.00 18.30  ? 140 LEU D CD1 1 
ATOM 6347 C CD2 . LEU D 1 140 ? 268.607 262.691 104.491 1.00 18.30  ? 140 LEU D CD2 1 
ATOM 6348 N N   . LEU D 1 141 ? 269.194 267.971 103.643 1.00 20.43  ? 141 LEU D N   1 
ATOM 6349 C CA  . LEU D 1 141 ? 269.475 269.253 104.266 1.00 20.43  ? 141 LEU D CA  1 
ATOM 6350 C C   . LEU D 1 141 ? 268.196 270.016 104.592 1.00 20.43  ? 141 LEU D C   1 
ATOM 6351 O O   . LEU D 1 141 ? 268.140 270.703 105.619 1.00 20.43  ? 141 LEU D O   1 
ATOM 6352 C CB  . LEU D 1 141 ? 270.410 270.060 103.375 1.00 20.43  ? 141 LEU D CB  1 
ATOM 6353 C CG  . LEU D 1 141 ? 271.865 269.618 103.550 1.00 20.43  ? 141 LEU D CG  1 
ATOM 6354 C CD1 . LEU D 1 141 ? 272.798 270.414 102.686 1.00 20.43  ? 141 LEU D CD1 1 
ATOM 6355 C CD2 . LEU D 1 141 ? 272.289 269.728 104.988 1.00 20.43  ? 141 LEU D CD2 1 
ATOM 6356 N N   . ASP D 1 142 ? 267.149 269.874 103.770 1.00 21.97  ? 142 ASP D N   1 
ATOM 6357 C CA  . ASP D 1 142 ? 265.841 270.409 104.134 1.00 21.97  ? 142 ASP D CA  1 
ATOM 6358 C C   . ASP D 1 142 ? 265.268 269.716 105.354 1.00 21.97  ? 142 ASP D C   1 
ATOM 6359 O O   . ASP D 1 142 ? 264.608 270.363 106.161 1.00 21.97  ? 142 ASP D O   1 
ATOM 6360 C CB  . ASP D 1 142 ? 264.859 270.276 102.983 1.00 21.97  ? 142 ASP D CB  1 
ATOM 6361 C CG  . ASP D 1 142 ? 265.227 271.129 101.817 1.00 21.97  ? 142 ASP D CG  1 
ATOM 6362 O OD1 . ASP D 1 142 ? 266.325 271.715 101.852 1.00 21.97  ? 142 ASP D OD1 1 
ATOM 6363 O OD2 . ASP D 1 142 ? 264.430 271.208 100.862 1.00 21.97  ? 142 ASP D OD2 1 
ATOM 6364 N N   . THR D 1 143 ? 265.529 268.422 105.519 1.00 20.24  ? 143 THR D N   1 
ATOM 6365 C CA  . THR D 1 143 ? 265.088 267.718 106.719 1.00 20.24  ? 143 THR D CA  1 
ATOM 6366 C C   . THR D 1 143 ? 265.790 268.237 107.964 1.00 20.24  ? 143 THR D C   1 
ATOM 6367 O O   . THR D 1 143 ? 265.156 268.454 109.007 1.00 20.24  ? 143 THR D O   1 
ATOM 6368 C CB  . THR D 1 143 ? 265.364 266.238 106.570 1.00 20.24  ? 143 THR D CB  1 
ATOM 6369 O OG1 . THR D 1 143 ? 264.944 265.809 105.278 1.00 20.24  ? 143 THR D OG1 1 
ATOM 6370 C CG2 . THR D 1 143 ? 264.638 265.483 107.625 1.00 20.24  ? 143 THR D CG2 1 
ATOM 6371 N N   . ALA D 1 144 ? 267.108 268.422 107.868 1.00 15.75  ? 144 ALA D N   1 
ATOM 6372 C CA  . ALA D 1 144 ? 267.893 268.874 109.008 1.00 15.75  ? 144 ALA D CA  1 
ATOM 6373 C C   . ALA D 1 144 ? 267.525 270.293 109.401 1.00 15.75  ? 144 ALA D C   1 
ATOM 6374 O O   . ALA D 1 144 ? 267.328 270.582 110.586 1.00 15.75  ? 144 ALA D O   1 
ATOM 6375 C CB  . ALA D 1 144 ? 269.378 268.779 108.680 1.00 15.75  ? 144 ALA D CB  1 
ATOM 6376 N N   . SER D 1 145 ? 267.400 271.187 108.417 1.00 20.67  ? 145 SER D N   1 
ATOM 6377 C CA  . SER D 1 145 ? 266.972 272.548 108.692 1.00 20.67  ? 145 SER D CA  1 
ATOM 6378 C C   . SER D 1 145 ? 265.489 272.641 109.009 1.00 20.67  ? 145 SER D C   1 
ATOM 6379 O O   . SER D 1 145 ? 265.048 273.658 109.541 1.00 20.67  ? 145 SER D O   1 
ATOM 6380 C CB  . SER D 1 145 ? 267.312 273.445 107.513 1.00 20.67  ? 145 SER D CB  1 
ATOM 6381 O OG  . SER D 1 145 ? 267.044 272.794 106.296 1.00 20.67  ? 145 SER D OG  1 
ATOM 6382 N N   . ALA D 1 146 ? 264.710 271.608 108.705 1.00 15.03  ? 146 ALA D N   1 
ATOM 6383 C CA  . ALA D 1 146 ? 263.332 271.565 109.159 1.00 15.03  ? 146 ALA D CA  1 
ATOM 6384 C C   . ALA D 1 146 ? 263.269 271.299 110.648 1.00 15.03  ? 146 ALA D C   1 
ATOM 6385 O O   . ALA D 1 146 ? 262.784 272.131 111.418 1.00 15.03  ? 146 ALA D O   1 
ATOM 6386 C CB  . ALA D 1 146 ? 262.567 270.490 108.397 1.00 15.03  ? 146 ALA D CB  1 
ATOM 6387 N N   . LEU D 1 147 ? 263.780 270.153 111.079 1.00 13.33  ? 147 LEU D N   1 
ATOM 6388 C CA  . LEU D 1 147 ? 263.531 269.737 112.450 1.00 13.33  ? 147 LEU D CA  1 
ATOM 6389 C C   . LEU D 1 147 ? 264.573 270.220 113.445 1.00 13.33  ? 147 LEU D C   1 
ATOM 6390 O O   . LEU D 1 147 ? 264.256 270.318 114.632 1.00 13.33  ? 147 LEU D O   1 
ATOM 6391 C CB  . LEU D 1 147 ? 263.439 268.217 112.534 1.00 13.33  ? 147 LEU D CB  1 
ATOM 6392 C CG  . LEU D 1 147 ? 262.304 267.533 111.783 1.00 13.33  ? 147 LEU D CG  1 
ATOM 6393 C CD1 . LEU D 1 147 ? 262.768 266.201 111.252 1.00 13.33  ? 147 LEU D CD1 1 
ATOM 6394 C CD2 . LEU D 1 147 ? 261.130 267.348 112.696 1.00 13.33  ? 147 LEU D CD2 1 
ATOM 6395 N N   . TYR D 1 148 ? 265.799 270.533 113.009 1.00 12.71  ? 148 TYR D N   1 
ATOM 6396 C CA  . TYR D 1 148 ? 266.894 270.727 113.955 1.00 12.71  ? 148 TYR D CA  1 
ATOM 6397 C C   . TYR D 1 148 ? 267.682 272.010 113.742 1.00 12.71  ? 148 TYR D C   1 
ATOM 6398 O O   . TYR D 1 148 ? 268.796 272.107 114.247 1.00 12.71  ? 148 TYR D O   1 
ATOM 6399 C CB  . TYR D 1 148 ? 267.858 269.543 113.906 1.00 12.71  ? 148 TYR D CB  1 
ATOM 6400 C CG  . TYR D 1 148 ? 267.184 268.264 114.249 1.00 12.71  ? 148 TYR D CG  1 
ATOM 6401 C CD1 . TYR D 1 148 ? 266.766 268.024 115.539 1.00 12.71  ? 148 TYR D CD1 1 
ATOM 6402 C CD2 . TYR D 1 148 ? 266.920 267.316 113.276 1.00 12.71  ? 148 TYR D CD2 1 
ATOM 6403 C CE1 . TYR D 1 148 ? 266.126 266.876 115.861 1.00 12.71  ? 148 TYR D CE1 1 
ATOM 6404 C CE2 . TYR D 1 148 ? 266.271 266.163 113.587 1.00 12.71  ? 148 TYR D CE2 1 
ATOM 6405 C CZ  . TYR D 1 148 ? 265.880 265.951 114.884 1.00 12.71  ? 148 TYR D CZ  1 
ATOM 6406 O OH  . TYR D 1 148 ? 265.232 264.802 115.222 1.00 12.71  ? 148 TYR D OH  1 
ATOM 6407 N N   . ARG D 1 149 ? 267.137 272.999 113.031 1.00 20.92  ? 149 ARG D N   1 
ATOM 6408 C CA  . ARG D 1 149 ? 267.882 274.226 112.755 1.00 20.92  ? 149 ARG D CA  1 
ATOM 6409 C C   . ARG D 1 149 ? 268.178 275.016 114.023 1.00 20.92  ? 149 ARG D C   1 
ATOM 6410 O O   . ARG D 1 149 ? 269.229 275.650 114.126 1.00 20.92  ? 149 ARG D O   1 
ATOM 6411 C CB  . ARG D 1 149 ? 267.103 275.077 111.757 1.00 20.92  ? 149 ARG D CB  1 
ATOM 6412 C CG  . ARG D 1 149 ? 267.709 276.414 111.419 1.00 20.92  ? 149 ARG D CG  1 
ATOM 6413 C CD  . ARG D 1 149 ? 266.904 277.137 110.365 1.00 20.92  ? 149 ARG D CD  1 
ATOM 6414 N NE  . ARG D 1 149 ? 267.572 277.092 109.071 1.00 20.92  ? 149 ARG D NE  1 
ATOM 6415 C CZ  . ARG D 1 149 ? 266.990 277.380 107.912 1.00 20.92  ? 149 ARG D CZ  1 
ATOM 6416 N NH1 . ARG D 1 149 ? 265.710 277.725 107.873 1.00 20.92  ? 149 ARG D NH1 1 
ATOM 6417 N NH2 . ARG D 1 149 ? 267.687 277.310 106.788 1.00 20.92  ? 149 ARG D NH2 1 
ATOM 6418 N N   . GLU D 1 150 ? 267.296 274.947 115.015 1.00 22.33  ? 150 GLU D N   1 
ATOM 6419 C CA  . GLU D 1 150 ? 267.542 275.654 116.267 1.00 22.33  ? 150 GLU D CA  1 
ATOM 6420 C C   . GLU D 1 150 ? 268.636 274.978 117.078 1.00 22.33  ? 150 GLU D C   1 
ATOM 6421 O O   . GLU D 1 150 ? 269.445 275.654 117.719 1.00 22.33  ? 150 GLU D O   1 
ATOM 6422 C CB  . GLU D 1 150 ? 266.250 275.737 117.077 1.00 22.33  ? 150 GLU D CB  1 
ATOM 6423 C CG  . GLU D 1 150 ? 266.362 276.478 118.398 1.00 22.33  ? 150 GLU D CG  1 
ATOM 6424 C CD  . GLU D 1 150 ? 266.365 275.547 119.601 1.00 22.33  ? 150 GLU D CD  1 
ATOM 6425 O OE1 . GLU D 1 150 ? 265.589 274.567 119.603 1.00 22.33  ? 150 GLU D OE1 1 
ATOM 6426 O OE2 . GLU D 1 150 ? 267.143 275.796 120.549 1.00 22.33  ? 150 GLU D OE2 1 
ATOM 6427 N N   . ALA D 1 151 ? 268.695 273.651 117.047 1.00 14.89  ? 151 ALA D N   1 
ATOM 6428 C CA  . ALA D 1 151 ? 269.658 272.915 117.850 1.00 14.89  ? 151 ALA D CA  1 
ATOM 6429 C C   . ALA D 1 151 ? 271.011 272.793 117.180 1.00 14.89  ? 151 ALA D C   1 
ATOM 6430 O O   . ALA D 1 151 ? 272.018 272.641 117.874 1.00 14.89  ? 151 ALA D O   1 
ATOM 6431 C CB  . ALA D 1 151 ? 269.128 271.522 118.169 1.00 14.89  ? 151 ALA D CB  1 
ATOM 6432 N N   . LEU D 1 152 ? 271.066 272.841 115.852 1.00 16.61  ? 152 LEU D N   1 
ATOM 6433 C CA  . LEU D 1 152 ? 272.354 272.835 115.177 1.00 16.61  ? 152 LEU D CA  1 
ATOM 6434 C C   . LEU D 1 152 ? 273.077 274.154 115.386 1.00 16.61  ? 152 LEU D C   1 
ATOM 6435 O O   . LEU D 1 152 ? 274.191 274.183 115.910 1.00 16.61  ? 152 LEU D O   1 
ATOM 6436 C CB  . LEU D 1 152 ? 272.175 272.559 113.691 1.00 16.61  ? 152 LEU D CB  1 
ATOM 6437 C CG  . LEU D 1 152 ? 271.765 271.152 113.293 1.00 16.61  ? 152 LEU D CG  1 
ATOM 6438 C CD1 . LEU D 1 152 ? 271.823 271.064 111.818 1.00 16.61  ? 152 LEU D CD1 1 
ATOM 6439 C CD2 . LEU D 1 152 ? 272.640 270.117 113.923 1.00 16.61  ? 152 LEU D CD2 1 
ATOM 6440 N N   . GLU D 1 153 ? 272.459 275.258 114.985 1.00 18.91  ? 153 GLU D N   1 
ATOM 6441 C CA  . GLU D 1 153 ? 273.019 276.590 115.203 1.00 18.91  ? 153 GLU D CA  1 
ATOM 6442 C C   . GLU D 1 153 ? 272.754 276.981 116.646 1.00 18.91  ? 153 GLU D C   1 
ATOM 6443 O O   . GLU D 1 153 ? 271.773 277.649 116.960 1.00 18.91  ? 153 GLU D O   1 
ATOM 6444 C CB  . GLU D 1 153 ? 272.408 277.592 114.240 1.00 18.91  ? 153 GLU D CB  1 
ATOM 6445 C CG  . GLU D 1 153 ? 272.035 276.991 112.920 1.00 18.91  ? 153 GLU D CG  1 
ATOM 6446 C CD  . GLU D 1 153 ? 271.349 277.976 112.008 1.00 18.91  ? 153 GLU D CD  1 
ATOM 6447 O OE1 . GLU D 1 153 ? 270.587 278.821 112.514 1.00 18.91  ? 153 GLU D OE1 1 
ATOM 6448 O OE2 . GLU D 1 153 ? 271.575 277.914 110.784 1.00 18.91  ? 153 GLU D OE2 1 
ATOM 6449 N N   . SER D 1 154 ? 273.649 276.578 117.541 1.00 18.87  ? 154 SER D N   1 
ATOM 6450 C CA  . SER D 1 154 ? 273.373 276.735 118.954 1.00 18.87  ? 154 SER D CA  1 
ATOM 6451 C C   . SER D 1 154 ? 274.688 276.699 119.701 1.00 18.87  ? 154 SER D C   1 
ATOM 6452 O O   . SER D 1 154 ? 275.585 275.949 119.299 1.00 18.87  ? 154 SER D O   1 
ATOM 6453 C CB  . SER D 1 154 ? 272.454 275.622 119.454 1.00 18.87  ? 154 SER D CB  1 
ATOM 6454 O OG  . SER D 1 154 ? 272.066 275.833 120.794 1.00 18.87  ? 154 SER D OG  1 
ATOM 6455 N N   . PRO D 1 155 ? 274.845 277.460 120.778 1.00 24.48  ? 155 PRO D N   1 
ATOM 6456 C CA  . PRO D 1 155 ? 276.118 277.448 121.497 1.00 24.48  ? 155 PRO D CA  1 
ATOM 6457 C C   . PRO D 1 155 ? 276.224 276.336 122.523 1.00 24.48  ? 155 PRO D C   1 
ATOM 6458 O O   . PRO D 1 155 ? 276.671 276.575 123.647 1.00 24.48  ? 155 PRO D O   1 
ATOM 6459 C CB  . PRO D 1 155 ? 276.129 278.817 122.173 1.00 24.48  ? 155 PRO D CB  1 
ATOM 6460 C CG  . PRO D 1 155 ? 274.713 279.039 122.490 1.00 24.48  ? 155 PRO D CG  1 
ATOM 6461 C CD  . PRO D 1 155 ? 273.924 278.455 121.350 1.00 24.48  ? 155 PRO D CD  1 
ATOM 6462 N N   . GLU D 1 156 ? 275.836 275.123 122.154 1.00 36.23  ? 156 GLU D N   1 
ATOM 6463 C CA  . GLU D 1 156 ? 275.998 273.974 123.026 1.00 36.23  ? 156 GLU D CA  1 
ATOM 6464 C C   . GLU D 1 156 ? 276.004 272.723 122.170 1.00 36.23  ? 156 GLU D C   1 
ATOM 6465 O O   . GLU D 1 156 ? 275.260 272.633 121.193 1.00 36.23  ? 156 GLU D O   1 
ATOM 6466 C CB  . GLU D 1 156 ? 274.883 273.893 124.068 1.00 36.23  ? 156 GLU D CB  1 
ATOM 6467 C CG  . GLU D 1 156 ? 273.514 274.204 123.532 1.00 36.23  ? 156 GLU D CG  1 
ATOM 6468 C CD  . GLU D 1 156 ? 272.433 273.914 124.540 1.00 36.23  ? 156 GLU D CD  1 
ATOM 6469 O OE1 . GLU D 1 156 ? 272.766 273.695 125.720 1.00 36.23  ? 156 GLU D OE1 1 
ATOM 6470 O OE2 . GLU D 1 156 ? 271.246 273.901 124.156 1.00 36.23  ? 156 GLU D OE2 1 
ATOM 6471 N N   . HIS D 1 157 ? 276.868 271.778 122.515 1.00 36.48  ? 157 HIS D N   1 
ATOM 6472 C CA  . HIS D 1 157 ? 276.744 270.450 121.938 1.00 36.48  ? 157 HIS D CA  1 
ATOM 6473 C C   . HIS D 1 157 ? 275.560 269.768 122.598 1.00 36.48  ? 157 HIS D C   1 
ATOM 6474 O O   . HIS D 1 157 ? 275.593 269.447 123.788 1.00 36.48  ? 157 HIS D O   1 
ATOM 6475 C CB  . HIS D 1 157 ? 278.030 269.645 122.099 1.00 36.48  ? 157 HIS D CB  1 
ATOM 6476 C CG  . HIS D 1 157 ? 278.678 269.783 123.439 1.00 36.48  ? 157 HIS D CG  1 
ATOM 6477 N ND1 . HIS D 1 157 ? 279.613 270.757 123.712 1.00 36.48  ? 157 HIS D ND1 1 
ATOM 6478 C CD2 . HIS D 1 157 ? 278.531 269.072 124.581 1.00 36.48  ? 157 HIS D CD2 1 
ATOM 6479 C CE1 . HIS D 1 157 ? 280.017 270.637 124.963 1.00 36.48  ? 157 HIS D CE1 1 
ATOM 6480 N NE2 . HIS D 1 157 ? 279.371 269.627 125.515 1.00 36.48  ? 157 HIS D NE2 1 
ATOM 6481 N N   . CYS D 1 158 ? 274.488 269.594 121.838 1.00 25.35  ? 158 CYS D N   1 
ATOM 6482 C CA  . CYS D 1 158 ? 273.301 268.974 122.397 1.00 25.35  ? 158 CYS D CA  1 
ATOM 6483 C C   . CYS D 1 158 ? 273.493 267.472 122.522 1.00 25.35  ? 158 CYS D C   1 
ATOM 6484 O O   . CYS D 1 158 ? 273.236 266.888 123.578 1.00 25.35  ? 158 CYS D O   1 
ATOM 6485 C CB  . CYS D 1 158 ? 272.097 269.305 121.522 1.00 25.35  ? 158 CYS D CB  1 
ATOM 6486 S SG  . CYS D 1 158 ? 271.749 271.063 121.399 1.00 25.35  ? 158 CYS D SG  1 
ATOM 6487 N N   . SER D 1 159 ? 273.968 266.842 121.459 1.00 15.53  ? 159 SER D N   1 
ATOM 6488 C CA  . SER D 1 159 ? 274.174 265.405 121.407 1.00 15.53  ? 159 SER D CA  1 
ATOM 6489 C C   . SER D 1 159 ? 275.225 265.139 120.346 1.00 15.53  ? 159 SER D C   1 
ATOM 6490 O O   . SER D 1 159 ? 275.458 265.998 119.492 1.00 15.53  ? 159 SER D O   1 
ATOM 6491 C CB  . SER D 1 159 ? 272.860 264.672 121.086 1.00 15.53  ? 159 SER D CB  1 
ATOM 6492 O OG  . SER D 1 159 ? 272.708 264.483 119.697 1.00 15.53  ? 159 SER D OG  1 
ATOM 6493 N N   . PRO D 1 160 ? 275.908 263.988 120.401 1.00 11.86  ? 160 PRO D N   1 
ATOM 6494 C CA  . PRO D 1 160 ? 276.973 263.707 119.426 1.00 11.86  ? 160 PRO D CA  1 
ATOM 6495 C C   . PRO D 1 160 ? 276.543 263.694 117.975 1.00 11.86  ? 160 PRO D C   1 
ATOM 6496 O O   . PRO D 1 160 ? 277.378 263.959 117.101 1.00 11.86  ? 160 PRO D O   1 
ATOM 6497 C CB  . PRO D 1 160 ? 277.460 262.328 119.857 1.00 11.86  ? 160 PRO D CB  1 
ATOM 6498 C CG  . PRO D 1 160 ? 277.232 262.307 121.279 1.00 11.86  ? 160 PRO D CG  1 
ATOM 6499 C CD  . PRO D 1 160 ? 276.001 263.071 121.549 1.00 11.86  ? 160 PRO D CD  1 
ATOM 6500 N N   . HIS D 1 161 ? 275.273 263.419 117.687 1.00 12.12  ? 161 HIS D N   1 
ATOM 6501 C CA  . HIS D 1 161 ? 274.803 263.495 116.314 1.00 12.12  ? 161 HIS D CA  1 
ATOM 6502 C C   . HIS D 1 161 ? 274.770 264.928 115.822 1.00 12.12  ? 161 HIS D C   1 
ATOM 6503 O O   . HIS D 1 161 ? 274.941 265.167 114.629 1.00 12.12  ? 161 HIS D O   1 
ATOM 6504 C CB  . HIS D 1 161 ? 273.430 262.860 116.188 1.00 12.12  ? 161 HIS D CB  1 
ATOM 6505 C CG  . HIS D 1 161 ? 273.314 261.537 116.869 1.00 12.12  ? 161 HIS D CG  1 
ATOM 6506 N ND1 . HIS D 1 161 ? 273.701 260.359 116.271 1.00 12.12  ? 161 HIS D ND1 1 
ATOM 6507 C CD2 . HIS D 1 161 ? 272.850 261.204 118.094 1.00 12.12  ? 161 HIS D CD2 1 
ATOM 6508 C CE1 . HIS D 1 161 ? 273.483 259.358 117.101 1.00 12.12  ? 161 HIS D CE1 1 
ATOM 6509 N NE2 . HIS D 1 161 ? 272.968 259.844 118.214 1.00 12.12  ? 161 HIS D NE2 1 
ATOM 6510 N N   . HIS D 1 162 ? 274.614 265.897 116.721 1.00 10.47  ? 162 HIS D N   1 
ATOM 6511 C CA  . HIS D 1 162 ? 274.699 267.290 116.302 1.00 10.47  ? 162 HIS D CA  1 
ATOM 6512 C C   . HIS D 1 162 ? 276.133 267.689 116.014 1.00 10.47  ? 162 HIS D C   1 
ATOM 6513 O O   . HIS D 1 162 ? 276.393 268.402 115.043 1.00 10.47  ? 162 HIS D O   1 
ATOM 6514 C CB  . HIS D 1 162 ? 274.106 268.195 117.367 1.00 10.47  ? 162 HIS D CB  1 
ATOM 6515 C CG  . HIS D 1 162 ? 272.652 267.969 117.603 1.00 10.47  ? 162 HIS D CG  1 
ATOM 6516 N ND1 . HIS D 1 162 ? 271.685 268.395 116.725 1.00 10.47  ? 162 HIS D ND1 1 
ATOM 6517 C CD2 . HIS D 1 162 ? 271.998 267.359 118.615 1.00 10.47  ? 162 HIS D CD2 1 
ATOM 6518 C CE1 . HIS D 1 162 ? 270.496 268.061 117.188 1.00 10.47  ? 162 HIS D CE1 1 
ATOM 6519 N NE2 . HIS D 1 162 ? 270.658 267.433 118.335 1.00 10.47  ? 162 HIS D NE2 1 
ATOM 6520 N N   . THR D 1 163 ? 277.075 267.246 116.853 1.00 10.90  ? 163 THR D N   1 
ATOM 6521 C CA  . THR D 1 163 ? 278.486 267.552 116.647 1.00 10.90  ? 163 THR D CA  1 
ATOM 6522 C C   . THR D 1 163 ? 279.013 266.906 115.378 1.00 10.90  ? 163 THR D C   1 
ATOM 6523 O O   . THR D 1 163 ? 279.910 267.448 114.731 1.00 10.90  ? 163 THR D O   1 
ATOM 6524 C CB  . THR D 1 163 ? 279.302 267.090 117.848 1.00 10.90  ? 163 THR D CB  1 
ATOM 6525 O OG1 . THR D 1 163 ? 278.626 267.447 119.053 1.00 10.90  ? 163 THR D OG1 1 
ATOM 6526 C CG2 . THR D 1 163 ? 280.636 267.756 117.859 1.00 10.90  ? 163 THR D CG2 1 
ATOM 6527 N N   . ALA D 1 164 ? 278.460 265.759 114.995 1.00 9.24   ? 164 ALA D N   1 
ATOM 6528 C CA  . ALA D 1 164 ? 278.819 265.173 113.712 1.00 9.24   ? 164 ALA D CA  1 
ATOM 6529 C C   . ALA D 1 164 ? 278.072 265.820 112.557 1.00 9.24   ? 164 ALA D C   1 
ATOM 6530 O O   . ALA D 1 164 ? 278.628 265.968 111.463 1.00 9.24   ? 164 ALA D O   1 
ATOM 6531 C CB  . ALA D 1 164 ? 278.543 263.681 113.744 1.00 9.24   ? 164 ALA D CB  1 
ATOM 6532 N N   . LEU D 1 165 ? 276.832 266.250 112.787 1.00 8.49   ? 165 LEU D N   1 
ATOM 6533 C CA  . LEU D 1 165 ? 276.010 266.800 111.721 1.00 8.49   ? 165 LEU D CA  1 
ATOM 6534 C C   . LEU D 1 165 ? 276.460 268.197 111.322 1.00 8.49   ? 165 LEU D C   1 
ATOM 6535 O O   . LEU D 1 165 ? 276.371 268.553 110.143 1.00 8.49   ? 165 LEU D O   1 
ATOM 6536 C CB  . LEU D 1 165 ? 274.555 266.800 112.174 1.00 8.49   ? 165 LEU D CB  1 
ATOM 6537 C CG  . LEU D 1 165 ? 273.412 266.711 111.178 1.00 8.49   ? 165 LEU D CG  1 
ATOM 6538 C CD1 . LEU D 1 165 ? 273.706 265.693 110.135 1.00 8.49   ? 165 LEU D CD1 1 
ATOM 6539 C CD2 . LEU D 1 165 ? 272.170 266.342 111.922 1.00 8.49   ? 165 LEU D CD2 1 
ATOM 6540 N N   . ARG D 1 166 ? 276.961 268.986 112.275 1.00 9.85   ? 166 ARG D N   1 
ATOM 6541 C CA  . ARG D 1 166 ? 277.499 270.305 111.959 1.00 9.85   ? 166 ARG D CA  1 
ATOM 6542 C C   . ARG D 1 166 ? 278.708 270.195 111.042 1.00 9.85   ? 166 ARG D C   1 
ATOM 6543 O O   . ARG D 1 166 ? 278.799 270.895 110.024 1.00 9.85   ? 166 ARG D O   1 
ATOM 6544 C CB  . ARG D 1 166 ? 277.870 271.034 113.244 1.00 9.85   ? 166 ARG D CB  1 
ATOM 6545 C CG  . ARG D 1 166 ? 276.708 271.576 114.020 1.00 9.85   ? 166 ARG D CG  1 
ATOM 6546 C CD  . ARG D 1 166 ? 277.038 271.665 115.481 1.00 9.85   ? 166 ARG D CD  1 
ATOM 6547 N NE  . ARG D 1 166 ? 275.905 272.069 116.295 1.00 9.85   ? 166 ARG D NE  1 
ATOM 6548 C CZ  . ARG D 1 166 ? 275.761 271.744 117.571 1.00 9.85   ? 166 ARG D CZ  1 
ATOM 6549 N NH1 . ARG D 1 166 ? 276.666 271.012 118.178 1.00 9.85   ? 166 ARG D NH1 1 
ATOM 6550 N NH2 . ARG D 1 166 ? 274.705 272.146 118.243 1.00 9.85   ? 166 ARG D NH2 1 
ATOM 6551 N N   . GLN D 1 167 ? 279.638 269.300 111.381 1.00 11.30  ? 167 GLN D N   1 
ATOM 6552 C CA  . GLN D 1 167 ? 280.802 269.065 110.539 1.00 11.30  ? 167 GLN D CA  1 
ATOM 6553 C C   . GLN D 1 167 ? 280.428 268.486 109.188 1.00 11.30  ? 167 GLN D C   1 
ATOM 6554 O O   . GLN D 1 167 ? 281.068 268.819 108.189 1.00 11.30  ? 167 GLN D O   1 
ATOM 6555 C CB  . GLN D 1 167 ? 281.796 268.153 111.243 1.00 11.30  ? 167 GLN D CB  1 
ATOM 6556 C CG  . GLN D 1 167 ? 282.835 268.873 112.059 1.00 11.30  ? 167 GLN D CG  1 
ATOM 6557 C CD  . GLN D 1 167 ? 282.284 269.552 113.270 1.00 11.30  ? 167 GLN D CD  1 
ATOM 6558 O OE1 . GLN D 1 167 ? 282.365 270.765 113.399 1.00 11.30  ? 167 GLN D OE1 1 
ATOM 6559 N NE2 . GLN D 1 167 ? 281.740 268.777 114.185 1.00 11.30  ? 167 GLN D NE2 1 
ATOM 6560 N N   . ALA D 1 168 ? 279.383 267.661 109.124 1.00 8.21   ? 168 ALA D N   1 
ATOM 6561 C CA  . ALA D 1 168 ? 278.948 267.132 107.835 1.00 8.21   ? 168 ALA D CA  1 
ATOM 6562 C C   . ALA D 1 168 ? 278.386 268.230 106.935 1.00 8.21   ? 168 ALA D C   1 
ATOM 6563 O O   . ALA D 1 168 ? 278.685 268.269 105.732 1.00 8.21   ? 168 ALA D O   1 
ATOM 6564 C CB  . ALA D 1 168 ? 277.921 266.029 108.059 1.00 8.21   ? 168 ALA D CB  1 
ATOM 6565 N N   . ILE D 1 169 ? 277.610 269.153 107.507 1.00 8.85   ? 169 ILE D N   1 
ATOM 6566 C CA  . ILE D 1 169 ? 277.042 270.238 106.712 1.00 8.85   ? 169 ILE D CA  1 
ATOM 6567 C C   . ILE D 1 169 ? 278.131 271.189 106.232 1.00 8.85   ? 169 ILE D C   1 
ATOM 6568 O O   . ILE D 1 169 ? 278.143 271.589 105.063 1.00 8.85   ? 169 ILE D O   1 
ATOM 6569 C CB  . ILE D 1 169 ? 275.964 270.975 107.519 1.00 8.85   ? 169 ILE D CB  1 
ATOM 6570 C CG1 . ILE D 1 169 ? 274.783 270.066 107.762 1.00 8.85   ? 169 ILE D CG1 1 
ATOM 6571 C CG2 . ILE D 1 169 ? 275.464 272.176 106.782 1.00 8.85   ? 169 ILE D CG2 1 
ATOM 6572 C CD1 . ILE D 1 169 ? 273.981 270.500 108.906 1.00 8.85   ? 169 ILE D CD1 1 
ATOM 6573 N N   . LEU D 1 170 ? 279.086 271.533 107.104 1.00 13.08  ? 170 LEU D N   1 
ATOM 6574 C CA  . LEU D 1 170 ? 280.158 272.438 106.692 1.00 13.08  ? 170 LEU D CA  1 
ATOM 6575 C C   . LEU D 1 170 ? 281.110 271.789 105.698 1.00 13.08  ? 170 LEU D C   1 
ATOM 6576 O O   . LEU D 1 170 ? 281.642 272.478 104.817 1.00 13.08  ? 170 LEU D O   1 
ATOM 6577 C CB  . LEU D 1 170 ? 280.938 272.913 107.902 1.00 13.08  ? 170 LEU D CB  1 
ATOM 6578 C CG  . LEU D 1 170 ? 280.123 273.714 108.894 1.00 13.08  ? 170 LEU D CG  1 
ATOM 6579 C CD1 . LEU D 1 170 ? 280.746 273.562 110.241 1.00 13.08  ? 170 LEU D CD1 1 
ATOM 6580 C CD2 . LEU D 1 170 ? 280.094 275.154 108.476 1.00 13.08  ? 170 LEU D CD2 1 
ATOM 6581 N N   . ALA D 1 171 ? 281.331 270.478 105.823 1.00 13.95  ? 171 ALA D N   1 
ATOM 6582 C CA  . ALA D 1 171 ? 282.117 269.746 104.840 1.00 13.95  ? 171 ALA D CA  1 
ATOM 6583 C C   . ALA D 1 171 ? 281.454 269.786 103.477 1.00 13.95  ? 171 ALA D C   1 
ATOM 6584 O O   . ALA D 1 171 ? 282.112 270.051 102.468 1.00 13.95  ? 171 ALA D O   1 
ATOM 6585 C CB  . ALA D 1 171 ? 282.301 268.305 105.295 1.00 13.95  ? 171 ALA D CB  1 
ATOM 6586 N N   . TRP D 1 172 ? 280.142 269.557 103.430 1.00 17.90  ? 172 TRP D N   1 
ATOM 6587 C CA  . TRP D 1 172 ? 279.450 269.666 102.152 1.00 17.90  ? 172 TRP D CA  1 
ATOM 6588 C C   . TRP D 1 172 ? 279.452 271.093 101.622 1.00 17.90  ? 172 TRP D C   1 
ATOM 6589 O O   . TRP D 1 172 ? 279.518 271.294 100.405 1.00 17.90  ? 172 TRP D O   1 
ATOM 6590 C CB  . TRP D 1 172 ? 278.021 269.157 102.268 1.00 17.90  ? 172 TRP D CB  1 
ATOM 6591 C CG  . TRP D 1 172 ? 277.303 269.191 100.969 1.00 17.90  ? 172 TRP D CG  1 
ATOM 6592 C CD1 . TRP D 1 172 ? 276.233 269.960 100.656 1.00 17.90  ? 172 TRP D CD1 1 
ATOM 6593 C CD2 . TRP D 1 172 ? 277.610 268.433 99.796  1.00 17.90  ? 172 TRP D CD2 1 
ATOM 6594 N NE1 . TRP D 1 172 ? 275.848 269.729 99.366  1.00 17.90  ? 172 TRP D NE1 1 
ATOM 6595 C CE2 . TRP D 1 172 ? 276.680 268.794 98.816  1.00 17.90  ? 172 TRP D CE2 1 
ATOM 6596 C CE3 . TRP D 1 172 ? 278.580 267.481 99.480  1.00 17.90  ? 172 TRP D CE3 1 
ATOM 6597 C CZ2 . TRP D 1 172 ? 276.682 268.236 97.551  1.00 17.90  ? 172 TRP D CZ2 1 
ATOM 6598 C CZ3 . TRP D 1 172 ? 278.584 266.935 98.222  1.00 17.90  ? 172 TRP D CZ3 1 
ATOM 6599 C CH2 . TRP D 1 172 ? 277.646 267.315 97.272  1.00 17.90  ? 172 TRP D CH2 1 
ATOM 6600 N N   . GLY D 1 173 ? 279.427 272.083 102.513 1.00 18.79  ? 173 GLY D N   1 
ATOM 6601 C CA  . GLY D 1 173 ? 279.494 273.467 102.076 1.00 18.79  ? 173 GLY D CA  1 
ATOM 6602 C C   . GLY D 1 173 ? 280.800 273.798 101.382 1.00 18.79  ? 173 GLY D C   1 
ATOM 6603 O O   . GLY D 1 173 ? 280.805 274.367 100.289 1.00 18.79  ? 173 GLY D O   1 
ATOM 6604 N N   . GLU D 1 174 ? 281.925 273.416 101.991 1.00 23.80  ? 174 GLU D N   1 
ATOM 6605 C CA  . GLU D 1 174 ? 283.210 273.703 101.359 1.00 23.80  ? 174 GLU D CA  1 
ATOM 6606 C C   . GLU D 1 174 ? 283.438 272.844 100.117 1.00 23.80  ? 174 GLU D C   1 
ATOM 6607 O O   . GLU D 1 174 ? 284.096 273.300 99.171  1.00 23.80  ? 174 GLU D O   1 
ATOM 6608 C CB  . GLU D 1 174 ? 284.356 273.557 102.363 1.00 23.80  ? 174 GLU D CB  1 
ATOM 6609 C CG  . GLU D 1 174 ? 284.524 272.190 102.980 1.00 23.80  ? 174 GLU D CG  1 
ATOM 6610 C CD  . GLU D 1 174 ? 285.406 272.195 104.229 1.00 23.80  ? 174 GLU D CD  1 
ATOM 6611 O OE1 . GLU D 1 174 ? 285.516 273.256 104.878 1.00 23.80  ? 174 GLU D OE1 1 
ATOM 6612 O OE2 . GLU D 1 174 ? 285.982 271.134 104.567 1.00 23.80  ? 174 GLU D OE2 1 
ATOM 6613 N N   . LEU D 1 175 ? 282.852 271.640 100.060 1.00 24.77  ? 175 LEU D N   1 
ATOM 6614 C CA  . LEU D 1 175 ? 282.884 270.875 98.812  1.00 24.77  ? 175 LEU D CA  1 
ATOM 6615 C C   . LEU D 1 175 ? 282.110 271.573 97.700  1.00 24.77  ? 175 LEU D C   1 
ATOM 6616 O O   . LEU D 1 175 ? 282.544 271.580 96.544  1.00 24.77  ? 175 LEU D O   1 
ATOM 6617 C CB  . LEU D 1 175 ? 282.345 269.461 99.017  1.00 24.77  ? 175 LEU D CB  1 
ATOM 6618 C CG  . LEU D 1 175 ? 283.366 268.345 99.250  1.00 24.77  ? 175 LEU D CG  1 
ATOM 6619 C CD1 . LEU D 1 175 ? 284.345 268.328 98.099  1.00 24.77  ? 175 LEU D CD1 1 
ATOM 6620 C CD2 . LEU D 1 175 ? 284.125 268.411 100.558 1.00 24.77  ? 175 LEU D CD2 1 
ATOM 6621 N N   . MET D 1 176 ? 280.988 272.201 98.027  1.00 29.89  ? 176 MET D N   1 
ATOM 6622 C CA  . MET D 1 176 ? 280.244 272.879 96.974  1.00 29.89  ? 176 MET D CA  1 
ATOM 6623 C C   . MET D 1 176 ? 280.878 274.205 96.570  1.00 29.89  ? 176 MET D C   1 
ATOM 6624 O O   . MET D 1 176 ? 280.733 274.620 95.414  1.00 29.89  ? 176 MET D O   1 
ATOM 6625 C CB  . MET D 1 176 ? 278.797 273.087 97.400  1.00 29.89  ? 176 MET D CB  1 
ATOM 6626 C CG  . MET D 1 176 ? 277.965 271.826 97.299  1.00 29.89  ? 176 MET D CG  1 
ATOM 6627 S SD  . MET D 1 176 ? 278.464 270.781 95.917  1.00 29.89  ? 176 MET D SD  1 
ATOM 6628 C CE  . MET D 1 176 ? 277.668 271.603 94.543  1.00 29.89  ? 176 MET D CE  1 
ATOM 6629 N N   . THR D 1 177 ? 281.593 274.878 97.479  1.00 28.85  ? 177 THR D N   1 
ATOM 6630 C CA  . THR D 1 177 ? 282.349 276.049 97.036  1.00 28.85  ? 177 THR D CA  1 
ATOM 6631 C C   . THR D 1 177 ? 283.535 275.655 96.170  1.00 28.85  ? 177 THR D C   1 
ATOM 6632 O O   . THR D 1 177 ? 283.888 276.394 95.249  1.00 28.85  ? 177 THR D O   1 
ATOM 6633 C CB  . THR D 1 177 ? 282.837 276.899 98.203  1.00 28.85  ? 177 THR D CB  1 
ATOM 6634 O OG1 . THR D 1 177 ? 283.885 276.217 98.896  1.00 28.85  ? 177 THR D OG1 1 
ATOM 6635 C CG2 . THR D 1 177 ? 281.715 277.248 99.136  1.00 28.85  ? 177 THR D CG2 1 
ATOM 6636 N N   . LEU D 1 178 ? 284.143 274.493 96.417  1.00 31.45  ? 178 LEU D N   1 
ATOM 6637 C CA  . LEU D 1 178 ? 285.137 274.004 95.466  1.00 31.45  ? 178 LEU D CA  1 
ATOM 6638 C C   . LEU D 1 178 ? 284.505 273.642 94.127  1.00 31.45  ? 178 LEU D C   1 
ATOM 6639 O O   . LEU D 1 178 ? 285.114 273.866 93.073  1.00 31.45  ? 178 LEU D O   1 
ATOM 6640 C CB  . LEU D 1 178 ? 285.874 272.805 96.044  1.00 31.45  ? 178 LEU D CB  1 
ATOM 6641 C CG  . LEU D 1 178 ? 286.690 271.919 95.104  1.00 31.45  ? 178 LEU D CG  1 
ATOM 6642 C CD1 . LEU D 1 178 ? 287.864 272.661 94.521  1.00 31.45  ? 178 LEU D CD1 1 
ATOM 6643 C CD2 . LEU D 1 178 ? 287.169 270.748 95.863  1.00 31.45  ? 178 LEU D CD2 1 
ATOM 6644 N N   . ALA D 1 179 ? 283.288 273.094 94.150  1.00 39.15  ? 179 ALA D N   1 
ATOM 6645 C CA  . ALA D 1 179 ? 282.601 272.756 92.908  1.00 39.15  ? 179 ALA D CA  1 
ATOM 6646 C C   . ALA D 1 179 ? 282.280 273.999 92.089  1.00 39.15  ? 179 ALA D C   1 
ATOM 6647 O O   . ALA D 1 179 ? 282.492 274.015 90.873  1.00 39.15  ? 179 ALA D O   1 
ATOM 6648 C CB  . ALA D 1 179 ? 281.328 271.973 93.209  1.00 39.15  ? 179 ALA D CB  1 
ATOM 6649 N N   . THR D 1 180 ? 281.815 275.066 92.733  1.00 48.28  ? 180 THR D N   1 
ATOM 6650 C CA  . THR D 1 180 ? 281.593 276.293 91.979  1.00 48.28  ? 180 THR D CA  1 
ATOM 6651 C C   . THR D 1 180 ? 282.893 277.007 91.632  1.00 48.28  ? 180 THR D C   1 
ATOM 6652 O O   . THR D 1 180 ? 282.909 277.777 90.666  1.00 48.28  ? 180 THR D O   1 
ATOM 6653 C CB  . THR D 1 180 ? 280.644 277.245 92.719  1.00 48.28  ? 180 THR D CB  1 
ATOM 6654 O OG1 . THR D 1 180 ? 280.208 278.266 91.816  1.00 48.28  ? 180 THR D OG1 1 
ATOM 6655 C CG2 . THR D 1 180 ? 281.298 277.908 93.911  1.00 48.28  ? 180 THR D CG2 1 
ATOM 6656 N N   . TRP D 1 181 ? 283.981 276.748 92.368  1.00 49.39  ? 181 TRP D N   1 
ATOM 6657 C CA  . TRP D 1 181 ? 285.292 277.247 91.970  1.00 49.39  ? 181 TRP D CA  1 
ATOM 6658 C C   . TRP D 1 181 ? 285.729 276.633 90.652  1.00 49.39  ? 181 TRP D C   1 
ATOM 6659 O O   . TRP D 1 181 ? 286.085 277.344 89.708  1.00 49.39  ? 181 TRP D O   1 
ATOM 6660 C CB  . TRP D 1 181 ? 286.321 276.938 93.053  1.00 49.39  ? 181 TRP D CB  1 
ATOM 6661 C CG  . TRP D 1 181 ? 287.700 277.363 92.686  1.00 49.39  ? 181 TRP D CG  1 
ATOM 6662 C CD1 . TRP D 1 181 ? 288.709 276.575 92.213  1.00 49.39  ? 181 TRP D CD1 1 
ATOM 6663 C CD2 . TRP D 1 181 ? 288.224 278.679 92.771  1.00 49.39  ? 181 TRP D CD2 1 
ATOM 6664 N NE1 . TRP D 1 181 ? 289.831 277.329 91.988  1.00 49.39  ? 181 TRP D NE1 1 
ATOM 6665 C CE2 . TRP D 1 181 ? 289.558 278.627 92.328  1.00 49.39  ? 181 TRP D CE2 1 
ATOM 6666 C CE3 . TRP D 1 181 ? 287.693 279.906 93.177  1.00 49.39  ? 181 TRP D CE3 1 
ATOM 6667 C CZ2 . TRP D 1 181 ? 290.365 279.753 92.280  1.00 49.39  ? 181 TRP D CZ2 1 
ATOM 6668 C CZ3 . TRP D 1 181 ? 288.495 281.017 93.129  1.00 49.39  ? 181 TRP D CZ3 1 
ATOM 6669 C CH2 . TRP D 1 181 ? 289.814 280.935 92.681  1.00 49.39  ? 181 TRP D CH2 1 
ATOM 6670 N N   . VAL D 1 182 ? 285.695 275.306 90.568  1.00 47.25  ? 182 VAL D N   1 
ATOM 6671 C CA  . VAL D 1 182 ? 286.162 274.646 89.358  1.00 47.25  ? 182 VAL D CA  1 
ATOM 6672 C C   . VAL D 1 182 ? 285.144 274.796 88.231  1.00 47.25  ? 182 VAL D C   1 
ATOM 6673 O O   . VAL D 1 182 ? 285.510 274.719 87.052  1.00 47.25  ? 182 VAL D O   1 
ATOM 6674 C CB  . VAL D 1 182 ? 286.507 273.181 89.684  1.00 47.25  ? 182 VAL D CB  1 
ATOM 6675 C CG1 . VAL D 1 182 ? 285.280 272.405 90.089  1.00 47.25  ? 182 VAL D CG1 1 
ATOM 6676 C CG2 . VAL D 1 182 ? 287.272 272.504 88.558  1.00 47.25  ? 182 VAL D CG2 1 
ATOM 6677 N N   . GLY D 1 183 ? 283.882 275.085 88.555  1.00 59.50  ? 183 GLY D N   1 
ATOM 6678 C CA  . GLY D 1 183 ? 282.921 275.395 87.514  1.00 59.50  ? 183 GLY D CA  1 
ATOM 6679 C C   . GLY D 1 183 ? 283.052 276.797 86.964  1.00 59.50  ? 183 GLY D C   1 
ATOM 6680 O O   . GLY D 1 183 ? 282.795 277.021 85.778  1.00 59.50  ? 183 GLY D O   1 
ATOM 6681 N N   . ASN D 1 184 ? 283.446 277.757 87.803  1.00 63.80  ? 184 ASN D N   1 
ATOM 6682 C CA  . ASN D 1 184 ? 283.606 279.126 87.327  1.00 63.80  ? 184 ASN D CA  1 
ATOM 6683 C C   . ASN D 1 184 ? 284.846 279.269 86.459  1.00 63.80  ? 184 ASN D C   1 
ATOM 6684 O O   . ASN D 1 184 ? 284.819 279.968 85.441  1.00 63.80  ? 184 ASN D O   1 
ATOM 6685 C CB  . ASN D 1 184 ? 283.670 280.090 88.509  1.00 63.80  ? 184 ASN D CB  1 
ATOM 6686 C CG  . ASN D 1 184 ? 282.302 280.527 88.974  1.00 63.80  ? 184 ASN D CG  1 
ATOM 6687 O OD1 . ASN D 1 184 ? 281.286 280.030 88.494  1.00 63.80  ? 184 ASN D OD1 1 
ATOM 6688 N ND2 . ASN D 1 184 ? 282.265 281.463 89.912  1.00 63.80  ? 184 ASN D ND2 1 
ATOM 6689 N N   . ASN D 1 185 ? 285.939 278.620 86.842  1.00 64.31  ? 185 ASN D N   1 
ATOM 6690 C CA  . ASN D 1 185 ? 287.184 278.726 86.094  1.00 64.31  ? 185 ASN D CA  1 
ATOM 6691 C C   . ASN D 1 185 ? 287.255 277.635 85.039  1.00 64.31  ? 185 ASN D C   1 
ATOM 6692 O O   . ASN D 1 185 ? 286.231 277.065 84.667  1.00 64.31  ? 185 ASN D O   1 
ATOM 6693 C CB  . ASN D 1 185 ? 288.385 278.642 87.037  1.00 64.31  ? 185 ASN D CB  1 
ATOM 6694 C CG  . ASN D 1 185 ? 288.458 279.819 87.984  1.00 64.31  ? 185 ASN D CG  1 
ATOM 6695 O OD1 . ASN D 1 185 ? 288.301 280.967 87.574  1.00 64.31  ? 185 ASN D OD1 1 
ATOM 6696 N ND2 . ASN D 1 185 ? 288.680 279.541 89.259  1.00 64.31  ? 185 ASN D ND2 1 
ATOM 6697 N N   . PRO D 1 194 ? 290.680 272.448 81.524  1.00 71.67  ? 194 PRO D N   1 
ATOM 6698 C CA  . PRO D 1 194 ? 290.412 273.174 80.278  1.00 71.67  ? 194 PRO D CA  1 
ATOM 6699 C C   . PRO D 1 194 ? 288.953 273.602 80.156  1.00 71.67  ? 194 PRO D C   1 
ATOM 6700 O O   . PRO D 1 194 ? 288.450 274.319 81.020  1.00 71.67  ? 194 PRO D O   1 
ATOM 6701 C CB  . PRO D 1 194 ? 290.779 272.156 79.192  1.00 71.67  ? 194 PRO D CB  1 
ATOM 6702 C CG  . PRO D 1 194 ? 290.692 270.828 79.863  1.00 71.67  ? 194 PRO D CG  1 
ATOM 6703 C CD  . PRO D 1 194 ? 291.117 271.065 81.276  1.00 71.67  ? 194 PRO D CD  1 
ATOM 6704 N N   . ALA D 1 195 ? 288.285 273.168 79.085  1.00 68.82  ? 195 ALA D N   1 
ATOM 6705 C CA  . ALA D 1 195 ? 286.873 273.461 78.884  1.00 68.82  ? 195 ALA D CA  1 
ATOM 6706 C C   . ALA D 1 195 ? 285.961 272.309 79.277  1.00 68.82  ? 195 ALA D C   1 
ATOM 6707 O O   . ALA D 1 195 ? 284.763 272.529 79.478  1.00 68.82  ? 195 ALA D O   1 
ATOM 6708 C CB  . ALA D 1 195 ? 286.609 273.832 77.421  1.00 68.82  ? 195 ALA D CB  1 
ATOM 6709 N N   . SER D 1 196 ? 286.497 271.095 79.393  1.00 69.90  ? 196 SER D N   1 
ATOM 6710 C CA  . SER D 1 196 ? 285.732 269.924 79.813  1.00 69.90  ? 196 SER D CA  1 
ATOM 6711 C C   . SER D 1 196 ? 285.945 269.614 81.286  1.00 69.90  ? 196 SER D C   1 
ATOM 6712 O O   . SER D 1 196 ? 286.032 268.450 81.684  1.00 69.90  ? 196 SER D O   1 
ATOM 6713 C CB  . SER D 1 196 ? 286.085 268.714 78.958  1.00 69.90  ? 196 SER D CB  1 
ATOM 6714 O OG  . SER D 1 196 ? 285.396 267.564 79.420  1.00 69.90  ? 196 SER D OG  1 
ATOM 6715 N N   . ARG D 1 197 ? 286.033 270.653 82.117  1.00 71.05  ? 197 ARG D N   1 
ATOM 6716 C CA  . ARG D 1 197 ? 286.181 270.503 83.558  1.00 71.05  ? 197 ARG D CA  1 
ATOM 6717 C C   . ARG D 1 197 ? 284.841 270.416 84.278  1.00 71.05  ? 197 ARG D C   1 
ATOM 6718 O O   . ARG D 1 197 ? 284.718 270.887 85.414  1.00 71.05  ? 197 ARG D O   1 
ATOM 6719 C CB  . ARG D 1 197 ? 287.020 271.648 84.123  1.00 71.05  ? 197 ARG D CB  1 
ATOM 6720 C CG  . ARG D 1 197 ? 286.640 273.020 83.604  1.00 71.05  ? 197 ARG D CG  1 
ATOM 6721 C CD  . ARG D 1 197 ? 287.543 274.082 84.201  1.00 71.05  ? 197 ARG D CD  1 
ATOM 6722 N NE  . ARG D 1 197 ? 288.781 274.254 83.447  1.00 71.05  ? 197 ARG D NE  1 
ATOM 6723 C CZ  . ARG D 1 197 ? 289.822 274.961 83.877  1.00 71.05  ? 197 ARG D CZ  1 
ATOM 6724 N NH1 . ARG D 1 197 ? 290.909 275.072 83.126  1.00 71.05  ? 197 ARG D NH1 1 
ATOM 6725 N NH2 . ARG D 1 197 ? 289.777 275.558 85.062  1.00 71.05  ? 197 ARG D NH2 1 
ATOM 6726 N N   . ASP D 1 198 ? 283.818 269.874 83.621  1.00 64.20  ? 198 ASP D N   1 
ATOM 6727 C CA  . ASP D 1 198 ? 282.564 269.504 84.261  1.00 64.20  ? 198 ASP D CA  1 
ATOM 6728 C C   . ASP D 1 198 ? 282.587 268.084 84.808  1.00 64.20  ? 198 ASP D C   1 
ATOM 6729 O O   . ASP D 1 198 ? 281.715 267.726 85.607  1.00 64.20  ? 198 ASP D O   1 
ATOM 6730 C CB  . ASP D 1 198 ? 281.414 269.641 83.264  1.00 64.20  ? 198 ASP D CB  1 
ATOM 6731 C CG  . ASP D 1 198 ? 281.691 268.917 81.962  1.00 64.20  ? 198 ASP D CG  1 
ATOM 6732 O OD1 . ASP D 1 198 ? 282.877 268.658 81.670  1.00 64.20  ? 198 ASP D OD1 1 
ATOM 6733 O OD2 . ASP D 1 198 ? 280.730 268.606 81.229  1.00 64.20  ? 198 ASP D OD2 1 
ATOM 6734 N N   . LEU D 1 199 ? 283.565 267.277 84.391  1.00 56.57  ? 199 LEU D N   1 
ATOM 6735 C CA  . LEU D 1 199 ? 283.663 265.902 84.864  1.00 56.57  ? 199 LEU D CA  1 
ATOM 6736 C C   . LEU D 1 199 ? 284.042 265.850 86.336  1.00 56.57  ? 199 LEU D C   1 
ATOM 6737 O O   . LEU D 1 199 ? 283.549 264.995 87.078  1.00 56.57  ? 199 LEU D O   1 
ATOM 6738 C CB  . LEU D 1 199 ? 284.680 265.138 84.023  1.00 56.57  ? 199 LEU D CB  1 
ATOM 6739 C CG  . LEU D 1 199 ? 284.768 263.638 84.276  1.00 56.57  ? 199 LEU D CG  1 
ATOM 6740 C CD1 . LEU D 1 199 ? 283.398 263.007 84.132  1.00 56.57  ? 199 LEU D CD1 1 
ATOM 6741 C CD2 . LEU D 1 199 ? 285.760 263.002 83.324  1.00 56.57  ? 199 LEU D CD2 1 
ATOM 6742 N N   . VAL D 1 200 ? 284.904 266.766 86.779  1.00 55.71  ? 200 VAL D N   1 
ATOM 6743 C CA  . VAL D 1 200 ? 285.237 266.861 88.195  1.00 55.71  ? 200 VAL D CA  1 
ATOM 6744 C C   . VAL D 1 200 ? 284.031 267.341 89.001  1.00 55.71  ? 200 VAL D C   1 
ATOM 6745 O O   . VAL D 1 200 ? 283.824 266.904 90.141  1.00 55.71  ? 200 VAL D O   1 
ATOM 6746 C CB  . VAL D 1 200 ? 286.482 267.758 88.358  1.00 55.71  ? 200 VAL D CB  1 
ATOM 6747 C CG1 . VAL D 1 200 ? 286.320 269.025 87.575  1.00 55.71  ? 200 VAL D CG1 1 
ATOM 6748 C CG2 . VAL D 1 200 ? 286.776 268.083 89.813  1.00 55.71  ? 200 VAL D CG2 1 
ATOM 6749 N N   . VAL D 1 201 ? 283.177 268.175 88.402  1.00 47.63  ? 201 VAL D N   1 
ATOM 6750 C CA  . VAL D 1 201 ? 281.960 268.607 89.082  1.00 47.63  ? 201 VAL D CA  1 
ATOM 6751 C C   . VAL D 1 201 ? 280.983 267.443 89.212  1.00 47.63  ? 201 VAL D C   1 
ATOM 6752 O O   . VAL D 1 201 ? 280.335 267.270 90.250  1.00 47.63  ? 201 VAL D O   1 
ATOM 6753 C CB  . VAL D 1 201 ? 281.340 269.806 88.341  1.00 47.63  ? 201 VAL D CB  1 
ATOM 6754 C CG1 . VAL D 1 201 ? 280.019 270.222 88.967  1.00 47.63  ? 201 VAL D CG1 1 
ATOM 6755 C CG2 . VAL D 1 201 ? 282.302 270.967 88.338  1.00 47.63  ? 201 VAL D CG2 1 
ATOM 6756 N N   . ASN D 1 202 ? 280.901 266.595 88.186  1.00 45.32  ? 202 ASN D N   1 
ATOM 6757 C CA  . ASN D 1 202 ? 280.087 265.388 88.300  1.00 45.32  ? 202 ASN D CA  1 
ATOM 6758 C C   . ASN D 1 202 ? 280.667 264.424 89.327  1.00 45.32  ? 202 ASN D C   1 
ATOM 6759 O O   . ASN D 1 202 ? 279.919 263.779 90.074  1.00 45.32  ? 202 ASN D O   1 
ATOM 6760 C CB  . ASN D 1 202 ? 279.971 264.709 86.942  1.00 45.32  ? 202 ASN D CB  1 
ATOM 6761 C CG  . ASN D 1 202 ? 279.304 263.361 87.028  1.00 45.32  ? 202 ASN D CG  1 
ATOM 6762 O OD1 . ASN D 1 202 ? 278.260 263.216 87.656  1.00 45.32  ? 202 ASN D OD1 1 
ATOM 6763 N ND2 . ASN D 1 202 ? 279.908 262.361 86.405  1.00 45.32  ? 202 ASN D ND2 1 
ATOM 6764 N N   . TYR D 1 203 ? 281.997 264.352 89.405  1.00 43.28  ? 203 TYR D N   1 
ATOM 6765 C CA  . TYR D 1 203 ? 282.654 263.467 90.360  1.00 43.28  ? 203 TYR D CA  1 
ATOM 6766 C C   . TYR D 1 203 ? 282.388 263.896 91.795  1.00 43.28  ? 203 TYR D C   1 
ATOM 6767 O O   . TYR D 1 203 ? 282.112 263.054 92.653  1.00 43.28  ? 203 TYR D O   1 
ATOM 6768 C CB  . TYR D 1 203 ? 284.154 263.429 90.091  1.00 43.28  ? 203 TYR D CB  1 
ATOM 6769 C CG  . TYR D 1 203 ? 284.932 262.604 91.087  1.00 43.28  ? 203 TYR D CG  1 
ATOM 6770 C CD1 . TYR D 1 203 ? 284.843 261.221 91.088  1.00 43.28  ? 203 TYR D CD1 1 
ATOM 6771 C CD2 . TYR D 1 203 ? 285.762 263.207 92.020  1.00 43.28  ? 203 TYR D CD2 1 
ATOM 6772 C CE1 . TYR D 1 203 ? 285.557 260.463 91.994  1.00 43.28  ? 203 TYR D CE1 1 
ATOM 6773 C CE2 . TYR D 1 203 ? 286.481 262.455 92.925  1.00 43.28  ? 203 TYR D CE2 1 
ATOM 6774 C CZ  . TYR D 1 203 ? 286.372 261.088 92.909  1.00 43.28  ? 203 TYR D CZ  1 
ATOM 6775 O OH  . TYR D 1 203 ? 287.080 260.339 93.811  1.00 43.28  ? 203 TYR D OH  1 
ATOM 6776 N N   . VAL D 1 204 ? 282.443 265.196 92.073  1.00 42.17  ? 204 VAL D N   1 
ATOM 6777 C CA  . VAL D 1 204 ? 282.142 265.621 93.435  1.00 42.17  ? 204 VAL D CA  1 
ATOM 6778 C C   . VAL D 1 204 ? 280.641 265.532 93.702  1.00 42.17  ? 204 VAL D C   1 
ATOM 6779 O O   . VAL D 1 204 ? 280.227 265.161 94.807  1.00 42.17  ? 204 VAL D O   1 
ATOM 6780 C CB  . VAL D 1 204 ? 282.718 267.024 93.721  1.00 42.17  ? 204 VAL D CB  1 
ATOM 6781 C CG1 . VAL D 1 204 ? 282.225 268.047 92.756  1.00 42.17  ? 204 VAL D CG1 1 
ATOM 6782 C CG2 . VAL D 1 204 ? 282.400 267.475 95.121  1.00 42.17  ? 204 VAL D CG2 1 
ATOM 6783 N N   . ASN D 1 205 ? 279.804 265.758 92.686  1.00 42.73  ? 205 ASN D N   1 
ATOM 6784 C CA  . ASN D 1 205 ? 278.364 265.704 92.886  1.00 42.73  ? 205 ASN D CA  1 
ATOM 6785 C C   . ASN D 1 205 ? 277.848 264.286 93.081  1.00 42.73  ? 205 ASN D C   1 
ATOM 6786 O O   . ASN D 1 205 ? 276.731 264.117 93.578  1.00 42.73  ? 205 ASN D O   1 
ATOM 6787 C CB  . ASN D 1 205 ? 277.655 266.358 91.702  1.00 42.73  ? 205 ASN D CB  1 
ATOM 6788 C CG  . ASN D 1 205 ? 277.459 267.844 91.893  1.00 42.73  ? 205 ASN D CG  1 
ATOM 6789 O OD1 . ASN D 1 205 ? 277.926 268.653 91.094  1.00 42.73  ? 205 ASN D OD1 1 
ATOM 6790 N ND2 . ASN D 1 205 ? 276.757 268.212 92.955  1.00 42.73  ? 205 ASN D ND2 1 
ATOM 6791 N N   . THR D 1 206 ? 278.618 263.266 92.704  1.00 38.41  ? 206 THR D N   1 
ATOM 6792 C CA  . THR D 1 206 ? 278.201 261.889 92.941  1.00 38.41  ? 206 THR D CA  1 
ATOM 6793 C C   . THR D 1 206 ? 279.031 261.172 93.999  1.00 38.41  ? 206 THR D C   1 
ATOM 6794 O O   . THR D 1 206 ? 278.471 260.685 94.984  1.00 38.41  ? 206 THR D O   1 
ATOM 6795 C CB  . THR D 1 206 ? 278.236 261.096 91.638  1.00 38.41  ? 206 THR D CB  1 
ATOM 6796 O OG1 . THR D 1 206 ? 279.591 260.976 91.193  1.00 38.41  ? 206 THR D OG1 1 
ATOM 6797 C CG2 . THR D 1 206 ? 277.393 261.775 90.582  1.00 38.41  ? 206 THR D CG2 1 
ATOM 6798 N N   . ASN D 1 207 ? 280.357 261.102 93.839  1.00 37.92  ? 207 ASN D N   1 
ATOM 6799 C CA  . ASN D 1 207 ? 281.159 260.132 94.581  1.00 37.92  ? 207 ASN D CA  1 
ATOM 6800 C C   . ASN D 1 207 ? 281.401 260.547 96.027  1.00 37.92  ? 207 ASN D C   1 
ATOM 6801 O O   . ASN D 1 207 ? 281.468 259.690 96.913  1.00 37.92  ? 207 ASN D O   1 
ATOM 6802 C CB  . ASN D 1 207 ? 282.487 259.916 93.867  1.00 37.92  ? 207 ASN D CB  1 
ATOM 6803 C CG  . ASN D 1 207 ? 282.328 259.175 92.562  1.00 37.92  ? 207 ASN D CG  1 
ATOM 6804 O OD1 . ASN D 1 207 ? 282.661 257.996 92.470  1.00 37.92  ? 207 ASN D OD1 1 
ATOM 6805 N ND2 . ASN D 1 207 ? 281.825 259.860 91.541  1.00 37.92  ? 207 ASN D ND2 1 
ATOM 6806 N N   . MET D 1 208 ? 281.568 261.839 96.286  1.00 39.47  ? 208 MET D N   1 
ATOM 6807 C CA  . MET D 1 208 ? 281.602 262.328 97.656  1.00 39.47  ? 208 MET D CA  1 
ATOM 6808 C C   . MET D 1 208 ? 280.214 262.647 98.167  1.00 39.47  ? 208 MET D C   1 
ATOM 6809 O O   . MET D 1 208 ? 279.975 262.621 99.386  1.00 39.47  ? 208 MET D O   1 
ATOM 6810 C CB  . MET D 1 208 ? 282.467 263.579 97.752  1.00 39.47  ? 208 MET D CB  1 
ATOM 6811 C CG  . MET D 1 208 ? 283.931 263.305 97.883  1.00 39.47  ? 208 MET D CG  1 
ATOM 6812 S SD  . MET D 1 208 ? 284.883 264.705 97.300  1.00 39.47  ? 208 MET D SD  1 
ATOM 6813 C CE  . MET D 1 208 ? 284.943 264.301 95.570  1.00 39.47  ? 208 MET D CE  1 
ATOM 6814 N N   . GLY D 1 209 ? 279.301 262.944 97.244  1.00 29.50  ? 209 GLY D N   1 
ATOM 6815 C CA  . GLY D 1 209 ? 277.921 263.163 97.614  1.00 29.50  ? 209 GLY D CA  1 
ATOM 6816 C C   . GLY D 1 209 ? 277.272 261.934 98.205  1.00 29.50  ? 209 GLY D C   1 
ATOM 6817 O O   . GLY D 1 209 ? 276.412 262.048 99.073  1.00 29.50  ? 209 GLY D O   1 
ATOM 6818 N N   . LEU D 1 210 ? 277.696 260.747 97.773  1.00 24.62  ? 210 LEU D N   1 
ATOM 6819 C CA  . LEU D 1 210 ? 277.157 259.523 98.352  1.00 24.62  ? 210 LEU D CA  1 
ATOM 6820 C C   . LEU D 1 210 ? 277.575 259.369 99.806  1.00 24.62  ? 210 LEU D C   1 
ATOM 6821 O O   . LEU D 1 210 ? 276.748 259.015 100.654 1.00 24.62  ? 210 LEU D O   1 
ATOM 6822 C CB  . LEU D 1 210 ? 277.600 258.320 97.533  1.00 24.62  ? 210 LEU D CB  1 
ATOM 6823 C CG  . LEU D 1 210 ? 277.369 256.943 98.141  1.00 24.62  ? 210 LEU D CG  1 
ATOM 6824 C CD1 . LEU D 1 210 ? 275.903 256.665 98.385  1.00 24.62  ? 210 LEU D CD1 1 
ATOM 6825 C CD2 . LEU D 1 210 ? 277.965 255.902 97.233  1.00 24.62  ? 210 LEU D CD2 1 
ATOM 6826 N N   . LYS D 1 211 ? 278.841 259.653 100.116 1.00 21.77  ? 211 LYS D N   1 
ATOM 6827 C CA  . LYS D 1 211 ? 279.302 259.550 101.494 1.00 21.77  ? 211 LYS D CA  1 
ATOM 6828 C C   . LYS D 1 211 ? 278.643 260.589 102.376 1.00 21.77  ? 211 LYS D C   1 
ATOM 6829 O O   . LYS D 1 211 ? 278.276 260.293 103.521 1.00 21.77  ? 211 LYS D O   1 
ATOM 6830 C CB  . LYS D 1 211 ? 280.812 259.707 101.559 1.00 21.77  ? 211 LYS D CB  1 
ATOM 6831 C CG  . LYS D 1 211 ? 281.570 258.668 100.791 1.00 21.77  ? 211 LYS D CG  1 
ATOM 6832 C CD  . LYS D 1 211 ? 282.865 258.332 101.491 1.00 21.77  ? 211 LYS D CD  1 
ATOM 6833 C CE  . LYS D 1 211 ? 283.855 257.711 100.534 1.00 21.77  ? 211 LYS D CE  1 
ATOM 6834 N NZ  . LYS D 1 211 ? 284.317 258.693 99.521  1.00 21.77  ? 211 LYS D NZ  1 
ATOM 6835 N N   . ILE D 1 212 ? 278.435 261.793 101.850 1.00 18.00  ? 212 ILE D N   1 
ATOM 6836 C CA  . ILE D 1 212 ? 277.755 262.785 102.665 1.00 18.00  ? 212 ILE D CA  1 
ATOM 6837 C C   . ILE D 1 212 ? 276.265 262.484 102.783 1.00 18.00  ? 212 ILE D C   1 
ATOM 6838 O O   . ILE D 1 212 ? 275.662 262.830 103.798 1.00 18.00  ? 212 ILE D O   1 
ATOM 6839 C CB  . ILE D 1 212 ? 278.047 264.199 102.136 1.00 18.00  ? 212 ILE D CB  1 
ATOM 6840 C CG1 . ILE D 1 212 ? 277.925 265.211 103.263 1.00 18.00  ? 212 ILE D CG1 1 
ATOM 6841 C CG2 . ILE D 1 212 ? 277.142 264.584 101.013 1.00 18.00  ? 212 ILE D CG2 1 
ATOM 6842 C CD1 . ILE D 1 212 ? 278.990 265.072 104.306 1.00 18.00  ? 212 ILE D CD1 1 
ATOM 6843 N N   . ARG D 1 213 ? 275.671 261.768 101.822 1.00 20.36  ? 213 ARG D N   1 
ATOM 6844 C CA  . ARG D 1 213 ? 274.267 261.405 101.934 1.00 20.36  ? 213 ARG D CA  1 
ATOM 6845 C C   . ARG D 1 213 ? 274.063 260.336 102.986 1.00 20.36  ? 213 ARG D C   1 
ATOM 6846 O O   . ARG D 1 213 ? 273.099 260.397 103.750 1.00 20.36  ? 213 ARG D O   1 
ATOM 6847 C CB  . ARG D 1 213 ? 273.738 260.924 100.594 1.00 20.36  ? 213 ARG D CB  1 
ATOM 6848 C CG  . ARG D 1 213 ? 273.228 262.012 99.737  1.00 20.36  ? 213 ARG D CG  1 
ATOM 6849 C CD  . ARG D 1 213 ? 273.262 261.608 98.305  1.00 20.36  ? 213 ARG D CD  1 
ATOM 6850 N NE  . ARG D 1 213 ? 272.725 260.276 98.123  1.00 20.36  ? 213 ARG D NE  1 
ATOM 6851 C CZ  . ARG D 1 213 ? 272.639 259.676 96.949  1.00 20.36  ? 213 ARG D CZ  1 
ATOM 6852 N NH1 . ARG D 1 213 ? 273.058 260.292 95.860  1.00 20.36  ? 213 ARG D NH1 1 
ATOM 6853 N NH2 . ARG D 1 213 ? 272.139 258.459 96.869  1.00 20.36  ? 213 ARG D NH2 1 
ATOM 6854 N N   . GLN D 1 214 ? 274.966 259.359 103.048 1.00 19.35  ? 214 GLN D N   1 
ATOM 6855 C CA  . GLN D 1 214 ? 274.907 258.373 104.122 1.00 19.35  ? 214 GLN D CA  1 
ATOM 6856 C C   . GLN D 1 214 ? 275.137 259.010 105.475 1.00 19.35  ? 214 GLN D C   1 
ATOM 6857 O O   . GLN D 1 214 ? 274.444 258.693 106.445 1.00 19.35  ? 214 GLN D O   1 
ATOM 6858 C CB  . GLN D 1 214 ? 275.949 257.293 103.911 1.00 19.35  ? 214 GLN D CB  1 
ATOM 6859 C CG  . GLN D 1 214 ? 275.886 256.634 102.599 1.00 19.35  ? 214 GLN D CG  1 
ATOM 6860 C CD  . GLN D 1 214 ? 276.995 255.668 102.438 1.00 19.35  ? 214 GLN D CD  1 
ATOM 6861 O OE1 . GLN D 1 214 ? 277.661 255.320 103.403 1.00 19.35  ? 214 GLN D OE1 1 
ATOM 6862 N NE2 . GLN D 1 214 ? 277.217 255.222 101.218 1.00 19.35  ? 214 GLN D NE2 1 
ATOM 6863 N N   . LEU D 1 215 ? 276.106 259.916 105.557 1.00 10.26  ? 215 LEU D N   1 
ATOM 6864 C CA  . LEU D 1 215 ? 276.439 260.531 106.830 1.00 10.26  ? 215 LEU D CA  1 
ATOM 6865 C C   . LEU D 1 215 ? 275.385 261.519 107.291 1.00 10.26  ? 215 LEU D C   1 
ATOM 6866 O O   . LEU D 1 215 ? 275.258 261.747 108.490 1.00 10.26  ? 215 LEU D O   1 
ATOM 6867 C CB  . LEU D 1 215 ? 277.794 261.209 106.699 1.00 10.26  ? 215 LEU D CB  1 
ATOM 6868 C CG  . LEU D 1 215 ? 278.560 261.777 107.879 1.00 10.26  ? 215 LEU D CG  1 
ATOM 6869 C CD1 . LEU D 1 215 ? 278.620 260.826 109.036 1.00 10.26  ? 215 LEU D CD1 1 
ATOM 6870 C CD2 . LEU D 1 215 ? 279.936 262.050 107.370 1.00 10.26  ? 215 LEU D CD2 1 
ATOM 6871 N N   . LEU D 1 216 ? 274.630 262.107 106.373 1.00 15.57  ? 216 LEU D N   1 
ATOM 6872 C CA  . LEU D 1 216 ? 273.516 262.953 106.772 1.00 15.57  ? 216 LEU D CA  1 
ATOM 6873 C C   . LEU D 1 216 ? 272.303 262.120 107.147 1.00 15.57  ? 216 LEU D C   1 
ATOM 6874 O O   . LEU D 1 216 ? 271.623 262.430 108.133 1.00 15.57  ? 216 LEU D O   1 
ATOM 6875 C CB  . LEU D 1 216 ? 273.154 263.919 105.647 1.00 15.57  ? 216 LEU D CB  1 
ATOM 6876 C CG  . LEU D 1 216 ? 273.994 265.169 105.417 1.00 15.57  ? 216 LEU D CG  1 
ATOM 6877 C CD1 . LEU D 1 216 ? 273.719 265.692 104.036 1.00 15.57  ? 216 LEU D CD1 1 
ATOM 6878 C CD2 . LEU D 1 216 ? 273.706 266.224 106.444 1.00 15.57  ? 216 LEU D CD2 1 
ATOM 6879 N N   . TRP D 1 217 ? 272.013 261.085 106.348 1.00 28.56  ? 217 TRP D N   1 
ATOM 6880 C CA  . TRP D 1 217 ? 270.884 260.200 106.592 1.00 28.56  ? 217 TRP D CA  1 
ATOM 6881 C C   . TRP D 1 217 ? 270.983 259.545 107.953 1.00 28.56  ? 217 TRP D C   1 
ATOM 6882 O O   . TRP D 1 217 ? 269.996 259.505 108.695 1.00 28.56  ? 217 TRP D O   1 
ATOM 6883 C CB  . TRP D 1 217 ? 270.822 259.135 105.499 1.00 28.56  ? 217 TRP D CB  1 
ATOM 6884 C CG  . TRP D 1 217 ? 269.700 258.176 105.643 1.00 28.56  ? 217 TRP D CG  1 
ATOM 6885 C CD1 . TRP D 1 217 ? 268.478 258.285 105.092 1.00 28.56  ? 217 TRP D CD1 1 
ATOM 6886 C CD2 . TRP D 1 217 ? 269.696 256.952 106.385 1.00 28.56  ? 217 TRP D CD2 1 
ATOM 6887 N NE1 . TRP D 1 217 ? 267.700 257.219 105.445 1.00 28.56  ? 217 TRP D NE1 1 
ATOM 6888 C CE2 . TRP D 1 217 ? 268.431 256.385 106.242 1.00 28.56  ? 217 TRP D CE2 1 
ATOM 6889 C CE3 . TRP D 1 217 ? 270.643 256.285 107.160 1.00 28.56  ? 217 TRP D CE3 1 
ATOM 6890 C CZ2 . TRP D 1 217 ? 268.087 255.192 106.843 1.00 28.56  ? 217 TRP D CZ2 1 
ATOM 6891 C CZ3 . TRP D 1 217 ? 270.296 255.110 107.757 1.00 28.56  ? 217 TRP D CZ3 1 
ATOM 6892 C CH2 . TRP D 1 217 ? 269.034 254.571 107.597 1.00 28.56  ? 217 TRP D CH2 1 
ATOM 6893 N N   . PHE D 1 218 ? 272.175 259.055 108.305 1.00 28.56  ? 218 PHE D N   1 
ATOM 6894 C CA  . PHE D 1 218 ? 272.357 258.326 109.551 1.00 28.56  ? 218 PHE D CA  1 
ATOM 6895 C C   . PHE D 1 218 ? 272.135 259.217 110.754 1.00 28.56  ? 218 PHE D C   1 
ATOM 6896 O O   . PHE D 1 218 ? 271.466 258.817 111.707 1.00 28.56  ? 218 PHE D O   1 
ATOM 6897 C CB  . PHE D 1 218 ? 273.749 257.713 109.593 1.00 28.56  ? 218 PHE D CB  1 
ATOM 6898 C CG  . PHE D 1 218 ? 274.014 256.913 110.821 1.00 28.56  ? 218 PHE D CG  1 
ATOM 6899 C CD1 . PHE D 1 218 ? 273.454 255.671 110.982 1.00 28.56  ? 218 PHE D CD1 1 
ATOM 6900 C CD2 . PHE D 1 218 ? 274.830 257.403 111.814 1.00 28.56  ? 218 PHE D CD2 1 
ATOM 6901 C CE1 . PHE D 1 218 ? 273.700 254.944 112.110 1.00 28.56  ? 218 PHE D CE1 1 
ATOM 6902 C CE2 . PHE D 1 218 ? 275.069 256.681 112.938 1.00 28.56  ? 218 PHE D CE2 1 
ATOM 6903 C CZ  . PHE D 1 218 ? 274.509 255.456 113.087 1.00 28.56  ? 218 PHE D CZ  1 
ATOM 6904 N N   . HIS D 1 219 ? 272.611 260.454 110.698 1.00 16.36  ? 219 HIS D N   1 
ATOM 6905 C CA  . HIS D 1 219 ? 272.517 261.308 111.870 1.00 16.36  ? 219 HIS D CA  1 
ATOM 6906 C C   . HIS D 1 219 ? 271.147 261.942 112.012 1.00 16.36  ? 219 HIS D C   1 
ATOM 6907 O O   . HIS D 1 219 ? 270.639 262.051 113.132 1.00 16.36  ? 219 HIS D O   1 
ATOM 6908 C CB  . HIS D 1 219 ? 273.605 262.358 111.823 1.00 16.36  ? 219 HIS D CB  1 
ATOM 6909 C CG  . HIS D 1 219 ? 274.953 261.796 112.097 1.00 16.36  ? 219 HIS D CG  1 
ATOM 6910 N ND1 . HIS D 1 219 ? 275.201 260.990 113.182 1.00 16.36  ? 219 HIS D ND1 1 
ATOM 6911 C CD2 . HIS D 1 219 ? 276.109 261.874 111.409 1.00 16.36  ? 219 HIS D CD2 1 
ATOM 6912 C CE1 . HIS D 1 219 ? 276.463 260.615 113.160 1.00 16.36  ? 219 HIS D CE1 1 
ATOM 6913 N NE2 . HIS D 1 219 ? 277.034 261.130 112.090 1.00 16.36  ? 219 HIS D NE2 1 
ATOM 6914 N N   . ILE D 1 220 ? 270.515 262.323 110.900 1.00 12.00  ? 220 ILE D N   1 
ATOM 6915 C CA  . ILE D 1 220 ? 269.137 262.802 110.955 1.00 12.00  ? 220 ILE D CA  1 
ATOM 6916 C C   . ILE D 1 220 ? 268.200 261.703 111.444 1.00 12.00  ? 220 ILE D C   1 
ATOM 6917 O O   . ILE D 1 220 ? 267.315 261.943 112.275 1.00 12.00  ? 220 ILE D O   1 
ATOM 6918 C CB  . ILE D 1 220 ? 268.722 263.338 109.578 1.00 12.00  ? 220 ILE D CB  1 
ATOM 6919 C CG1 . ILE D 1 220 ? 269.447 264.632 109.302 1.00 12.00  ? 220 ILE D CG1 1 
ATOM 6920 C CG2 . ILE D 1 220 ? 267.259 263.600 109.507 1.00 12.00  ? 220 ILE D CG2 1 
ATOM 6921 C CD1 . ILE D 1 220 ? 269.455 264.984 107.877 1.00 12.00  ? 220 ILE D CD1 1 
ATOM 6922 N N   . SER D 1 221 ? 268.419 260.468 110.993 1.00 11.36  ? 221 SER D N   1 
ATOM 6923 C CA  . SER D 1 221 ? 267.550 259.376 111.391 1.00 11.36  ? 221 SER D CA  1 
ATOM 6924 C C   . SER D 1 221 ? 267.777 258.971 112.838 1.00 11.36  ? 221 SER D C   1 
ATOM 6925 O O   . SER D 1 221 ? 266.821 258.637 113.538 1.00 11.36  ? 221 SER D O   1 
ATOM 6926 C CB  . SER D 1 221 ? 267.767 258.214 110.445 1.00 11.36  ? 221 SER D CB  1 
ATOM 6927 O OG  . SER D 1 221 ? 267.603 258.677 109.121 1.00 11.36  ? 221 SER D OG  1 
ATOM 6928 N N   . CYS D 1 222 ? 269.021 259.010 113.321 1.00 9.85   ? 222 CYS D N   1 
ATOM 6929 C CA  . CYS D 1 222 ? 269.246 258.733 114.734 1.00 9.85   ? 222 CYS D CA  1 
ATOM 6930 C C   . CYS D 1 222 ? 268.724 259.839 115.625 1.00 9.85   ? 222 CYS D C   1 
ATOM 6931 O O   . CYS D 1 222 ? 268.380 259.582 116.781 1.00 9.85   ? 222 CYS D O   1 
ATOM 6932 C CB  . CYS D 1 222 ? 270.720 258.506 115.021 1.00 9.85   ? 222 CYS D CB  1 
ATOM 6933 S SG  . CYS D 1 222 ? 271.408 257.022 114.319 1.00 9.85   ? 222 CYS D SG  1 
ATOM 6934 N N   . LEU D 1 223 ? 268.667 261.068 115.124 1.00 9.69   ? 223 LEU D N   1 
ATOM 6935 C CA  . LEU D 1 223 ? 268.085 262.141 115.917 1.00 9.69   ? 223 LEU D CA  1 
ATOM 6936 C C   . LEU D 1 223 ? 266.575 261.990 115.998 1.00 9.69   ? 223 LEU D C   1 
ATOM 6937 O O   . LEU D 1 223 ? 265.984 262.110 117.077 1.00 9.69   ? 223 LEU D O   1 
ATOM 6938 C CB  . LEU D 1 223 ? 268.463 263.486 115.312 1.00 9.69   ? 223 LEU D CB  1 
ATOM 6939 C CG  . LEU D 1 223 ? 269.836 263.956 115.745 1.00 9.69   ? 223 LEU D CG  1 
ATOM 6940 C CD1 . LEU D 1 223 ? 270.290 265.113 114.910 1.00 9.69   ? 223 LEU D CD1 1 
ATOM 6941 C CD2 . LEU D 1 223 ? 269.778 264.321 117.197 1.00 9.69   ? 223 LEU D CD2 1 
ATOM 6942 N N   . THR D 1 224 ? 265.941 261.701 114.862 1.00 9.14   ? 224 THR D N   1 
ATOM 6943 C CA  . THR D 1 224 ? 264.490 261.620 114.799 1.00 9.14   ? 224 THR D CA  1 
ATOM 6944 C C   . THR D 1 224 ? 263.971 260.384 115.511 1.00 9.14   ? 224 THR D C   1 
ATOM 6945 O O   . THR D 1 224 ? 263.156 260.483 116.430 1.00 9.14   ? 224 THR D O   1 
ATOM 6946 C CB  . THR D 1 224 ? 264.043 261.625 113.344 1.00 9.14   ? 224 THR D CB  1 
ATOM 6947 O OG1 . THR D 1 224 ? 264.805 262.586 112.616 1.00 9.14   ? 224 THR D OG1 1 
ATOM 6948 C CG2 . THR D 1 224 ? 262.610 261.990 113.249 1.00 9.14   ? 224 THR D CG2 1 
ATOM 6949 N N   . PHE D 1 225 ? 264.441 259.207 115.116 1.00 8.84   ? 225 PHE D N   1 
ATOM 6950 C CA  . PHE D 1 225 ? 263.812 257.957 115.505 1.00 8.84   ? 225 PHE D CA  1 
ATOM 6951 C C   . PHE D 1 225 ? 264.501 257.243 116.650 1.00 8.84   ? 225 PHE D C   1 
ATOM 6952 O O   . PHE D 1 225 ? 263.991 256.227 117.112 1.00 8.84   ? 225 PHE D O   1 
ATOM 6953 C CB  . PHE D 1 225 ? 263.731 257.034 114.301 1.00 8.84   ? 225 PHE D CB  1 
ATOM 6954 C CG  . PHE D 1 225 ? 262.983 257.629 113.169 1.00 8.84   ? 225 PHE D CG  1 
ATOM 6955 C CD1 . PHE D 1 225 ? 261.616 257.731 113.224 1.00 8.84   ? 225 PHE D CD1 1 
ATOM 6956 C CD2 . PHE D 1 225 ? 263.645 258.117 112.068 1.00 8.84   ? 225 PHE D CD2 1 
ATOM 6957 C CE1 . PHE D 1 225 ? 260.925 258.290 112.198 1.00 8.84   ? 225 PHE D CE1 1 
ATOM 6958 C CE2 . PHE D 1 225 ? 262.953 258.682 111.040 1.00 8.84   ? 225 PHE D CE2 1 
ATOM 6959 C CZ  . PHE D 1 225 ? 261.590 258.764 111.110 1.00 8.84   ? 225 PHE D CZ  1 
ATOM 6960 N N   . GLY D 1 226 ? 265.615 257.739 117.130 1.00 11.18  ? 226 GLY D N   1 
ATOM 6961 C CA  . GLY D 1 226 ? 266.293 257.020 118.185 1.00 11.18  ? 226 GLY D CA  1 
ATOM 6962 C C   . GLY D 1 226 ? 267.395 256.152 117.625 1.00 11.18  ? 226 GLY D C   1 
ATOM 6963 O O   . GLY D 1 226 ? 267.329 255.672 116.493 1.00 11.18  ? 226 GLY D O   1 
ATOM 6964 N N   . ARG D 1 227 ? 268.432 255.941 118.429 1.00 18.41  ? 227 ARG D N   1 
ATOM 6965 C CA  . ARG D 1 227 ? 269.621 255.277 117.917 1.00 18.41  ? 227 ARG D CA  1 
ATOM 6966 C C   . ARG D 1 227 ? 269.445 253.776 117.818 1.00 18.41  ? 227 ARG D C   1 
ATOM 6967 O O   . ARG D 1 227 ? 269.980 253.164 116.894 1.00 18.41  ? 227 ARG D O   1 
ATOM 6968 C CB  . ARG D 1 227 ? 270.819 255.598 118.798 1.00 18.41  ? 227 ARG D CB  1 
ATOM 6969 C CG  . ARG D 1 227 ? 272.145 255.576 118.082 1.00 18.41  ? 227 ARG D CG  1 
ATOM 6970 C CD  . ARG D 1 227 ? 273.261 255.865 119.065 1.00 18.41  ? 227 ARG D CD  1 
ATOM 6971 N NE  . ARG D 1 227 ? 273.089 255.107 120.296 1.00 18.41  ? 227 ARG D NE  1 
ATOM 6972 C CZ  . ARG D 1 227 ? 273.458 253.842 120.460 1.00 18.41  ? 227 ARG D CZ  1 
ATOM 6973 N NH1 . ARG D 1 227 ? 273.250 253.241 121.622 1.00 18.41  ? 227 ARG D NH1 1 
ATOM 6974 N NH2 . ARG D 1 227 ? 274.039 253.180 119.470 1.00 18.41  ? 227 ARG D NH2 1 
ATOM 6975 N N   . GLU D 1 228 ? 268.715 253.169 118.751 1.00 22.09  ? 228 GLU D N   1 
ATOM 6976 C CA  . GLU D 1 228 ? 268.466 251.735 118.681 1.00 22.09  ? 228 GLU D CA  1 
ATOM 6977 C C   . GLU D 1 228 ? 267.559 251.386 117.517 1.00 22.09  ? 228 GLU D C   1 
ATOM 6978 O O   . GLU D 1 228 ? 267.735 250.334 116.891 1.00 22.09  ? 228 GLU D O   1 
ATOM 6979 C CB  . GLU D 1 228 ? 267.841 251.244 119.980 1.00 22.09  ? 228 GLU D CB  1 
ATOM 6980 C CG  . GLU D 1 228 ? 268.756 251.309 121.185 1.00 22.09  ? 228 GLU D CG  1 
ATOM 6981 C CD  . GLU D 1 228 ? 268.731 252.656 121.876 1.00 22.09  ? 228 GLU D CD  1 
ATOM 6982 O OE1 . GLU D 1 228 ? 267.938 253.523 121.459 1.00 22.09  ? 228 GLU D OE1 1 
ATOM 6983 O OE2 . GLU D 1 228 ? 269.509 252.852 122.830 1.00 22.09  ? 228 GLU D OE2 1 
ATOM 6984 N N   . THR D 1 229 ? 266.605 252.264 117.208 1.00 12.32  ? 229 THR D N   1 
ATOM 6985 C CA  . THR D 1 229 ? 265.672 252.021 116.119 1.00 12.32  ? 229 THR D CA  1 
ATOM 6986 C C   . THR D 1 229 ? 266.372 252.029 114.775 1.00 12.32  ? 229 THR D C   1 
ATOM 6987 O O   . THR D 1 229 ? 266.080 251.190 113.924 1.00 12.32  ? 229 THR D O   1 
ATOM 6988 C CB  . THR D 1 229 ? 264.573 253.062 116.146 1.00 12.32  ? 229 THR D CB  1 
ATOM 6989 O OG1 . THR D 1 229 ? 264.017 253.113 117.461 1.00 12.32  ? 229 THR D OG1 1 
ATOM 6990 C CG2 . THR D 1 229 ? 263.497 252.717 115.163 1.00 12.32  ? 229 THR D CG2 1 
ATOM 6991 N N   . VAL D 1 230 ? 267.319 252.945 114.571 1.00 11.97  ? 230 VAL D N   1 
ATOM 6992 C CA  . VAL D 1 230 ? 268.028 252.973 113.299 1.00 11.97  ? 230 VAL D CA  1 
ATOM 6993 C C   . VAL D 1 230 ? 268.942 251.774 113.188 1.00 11.97  ? 230 VAL D C   1 
ATOM 6994 O O   . VAL D 1 230 ? 269.068 251.174 112.114 1.00 11.97  ? 230 VAL D O   1 
ATOM 6995 C CB  . VAL D 1 230 ? 268.792 254.295 113.146 1.00 11.97  ? 230 VAL D CB  1 
ATOM 6996 C CG1 . VAL D 1 230 ? 269.448 254.381 111.797 1.00 11.97  ? 230 VAL D CG1 1 
ATOM 6997 C CG2 . VAL D 1 230 ? 267.847 255.422 113.291 1.00 11.97  ? 230 VAL D CG2 1 
ATOM 6998 N N   . LEU D 1 231 ? 269.511 251.339 114.307 1.00 10.96  ? 231 LEU D N   1 
ATOM 6999 C CA  . LEU D 1 231 ? 270.449 250.231 114.256 1.00 10.96  ? 231 LEU D CA  1 
ATOM 7000 C C   . LEU D 1 231 ? 269.751 248.897 114.046 1.00 10.96  ? 231 LEU D C   1 
ATOM 7001 O O   . LEU D 1 231 ? 270.331 248.001 113.431 1.00 10.96  ? 231 LEU D O   1 
ATOM 7002 C CB  . LEU D 1 231 ? 271.293 250.208 115.523 1.00 10.96  ? 231 LEU D CB  1 
ATOM 7003 C CG  . LEU D 1 231 ? 272.370 251.287 115.568 1.00 10.96  ? 231 LEU D CG  1 
ATOM 7004 C CD1 . LEU D 1 231 ? 273.284 251.012 116.710 1.00 10.96  ? 231 LEU D CD1 1 
ATOM 7005 C CD2 . LEU D 1 231 ? 273.141 251.341 114.276 1.00 10.96  ? 231 LEU D CD2 1 
ATOM 7006 N N   . GLU D 1 232 ? 268.519 248.738 114.523 1.00 11.78  ? 232 GLU D N   1 
ATOM 7007 C CA  . GLU D 1 232 ? 267.800 247.513 114.206 1.00 11.78  ? 232 GLU D CA  1 
ATOM 7008 C C   . GLU D 1 232 ? 267.024 247.604 112.906 1.00 11.78  ? 232 GLU D C   1 
ATOM 7009 O O   . GLU D 1 232 ? 266.781 246.570 112.275 1.00 11.78  ? 232 GLU D O   1 
ATOM 7010 C CB  . GLU D 1 232 ? 266.870 247.118 115.349 1.00 11.78  ? 232 GLU D CB  1 
ATOM 7011 C CG  . GLU D 1 232 ? 265.719 248.044 115.598 1.00 11.78  ? 232 GLU D CG  1 
ATOM 7012 C CD  . GLU D 1 232 ? 265.210 247.941 117.023 1.00 11.78  ? 232 GLU D CD  1 
ATOM 7013 O OE1 . GLU D 1 232 ? 265.990 247.496 117.890 1.00 11.78  ? 232 GLU D OE1 1 
ATOM 7014 O OE2 . GLU D 1 232 ? 264.039 248.296 117.277 1.00 11.78  ? 232 GLU D OE2 1 
ATOM 7015 N N   . TYR D 1 233 ? 266.673 248.808 112.460 1.00 11.98  ? 233 TYR D N   1 
ATOM 7016 C CA  . TYR D 1 233 ? 266.135 248.973 111.121 1.00 11.98  ? 233 TYR D CA  1 
ATOM 7017 C C   . TYR D 1 233 ? 267.172 248.639 110.067 1.00 11.98  ? 233 TYR D C   1 
ATOM 7018 O O   . TYR D 1 233 ? 266.819 248.153 108.993 1.00 11.98  ? 233 TYR D O   1 
ATOM 7019 C CB  . TYR D 1 233 ? 265.628 250.402 110.931 1.00 11.98  ? 233 TYR D CB  1 
ATOM 7020 C CG  . TYR D 1 233 ? 265.435 250.794 109.495 1.00 11.98  ? 233 TYR D CG  1 
ATOM 7021 C CD1 . TYR D 1 233 ? 264.383 250.302 108.770 1.00 11.98  ? 233 TYR D CD1 1 
ATOM 7022 C CD2 . TYR D 1 233 ? 266.322 251.640 108.863 1.00 11.98  ? 233 TYR D CD2 1 
ATOM 7023 C CE1 . TYR D 1 233 ? 264.211 250.647 107.471 1.00 11.98  ? 233 TYR D CE1 1 
ATOM 7024 C CE2 . TYR D 1 233 ? 266.159 251.979 107.564 1.00 11.98  ? 233 TYR D CE2 1 
ATOM 7025 C CZ  . TYR D 1 233 ? 265.103 251.480 106.876 1.00 11.98  ? 233 TYR D CZ  1 
ATOM 7026 O OH  . TYR D 1 233 ? 264.926 251.826 105.571 1.00 11.98  ? 233 TYR D OH  1 
ATOM 7027 N N   . LEU D 1 234 ? 268.447 248.885 110.353 1.00 11.20  ? 234 LEU D N   1 
ATOM 7028 C CA  . LEU D 1 234 ? 269.482 248.544 109.390 1.00 11.20  ? 234 LEU D CA  1 
ATOM 7029 C C   . LEU D 1 234 ? 269.595 247.038 109.212 1.00 11.20  ? 234 LEU D C   1 
ATOM 7030 O O   . LEU D 1 234 ? 269.745 246.554 108.087 1.00 11.20  ? 234 LEU D O   1 
ATOM 7031 C CB  . LEU D 1 234 ? 270.805 249.141 109.835 1.00 11.20  ? 234 LEU D CB  1 
ATOM 7032 C CG  . LEU D 1 234 ? 271.012 250.582 109.406 1.00 11.20  ? 234 LEU D CG  1 
ATOM 7033 C CD1 . LEU D 1 234 ? 271.938 251.280 110.345 1.00 11.20  ? 234 LEU D CD1 1 
ATOM 7034 C CD2 . LEU D 1 234 ? 271.575 250.569 108.043 1.00 11.20  ? 234 LEU D CD2 1 
ATOM 7035 N N   . VAL D 1 235 ? 269.444 246.282 110.297 1.00 13.64  ? 235 VAL D N   1 
ATOM 7036 C CA  . VAL D 1 235 ? 269.449 244.828 110.202 1.00 13.64  ? 235 VAL D CA  1 
ATOM 7037 C C   . VAL D 1 235 ? 268.194 244.323 109.505 1.00 13.64  ? 235 VAL D C   1 
ATOM 7038 O O   . VAL D 1 235 ? 268.261 243.400 108.688 1.00 13.64  ? 235 VAL D O   1 
ATOM 7039 C CB  . VAL D 1 235 ? 269.603 244.210 111.597 1.00 13.64  ? 235 VAL D CB  1 
ATOM 7040 C CG1 . VAL D 1 235 ? 269.875 242.740 111.490 1.00 13.64  ? 235 VAL D CG1 1 
ATOM 7041 C CG2 . VAL D 1 235 ? 270.717 244.883 112.334 1.00 13.64  ? 235 VAL D CG2 1 
ATOM 7042 N N   . SER D 1 236 ? 267.033 244.912 109.810 1.00 12.31  ? 236 SER D N   1 
ATOM 7043 C CA  . SER D 1 236 ? 265.794 244.442 109.196 1.00 12.31  ? 236 SER D CA  1 
ATOM 7044 C C   . SER D 1 236 ? 265.741 244.763 107.711 1.00 12.31  ? 236 SER D C   1 
ATOM 7045 O O   . SER D 1 236 ? 265.284 243.937 106.914 1.00 12.31  ? 236 SER D O   1 
ATOM 7046 C CB  . SER D 1 236 ? 264.594 245.033 109.913 1.00 12.31  ? 236 SER D CB  1 
ATOM 7047 O OG  . SER D 1 236 ? 264.706 244.833 111.305 1.00 12.31  ? 236 SER D OG  1 
ATOM 7048 N N   . PHE D 1 237 ? 266.233 245.933 107.308 1.00 28.56  ? 237 PHE D N   1 
ATOM 7049 C CA  . PHE D 1 237 ? 266.353 246.210 105.887 1.00 28.56  ? 237 PHE D CA  1 
ATOM 7050 C C   . PHE D 1 237 ? 267.426 245.353 105.252 1.00 28.56  ? 237 PHE D C   1 
ATOM 7051 O O   . PHE D 1 237 ? 267.325 245.035 104.064 1.00 28.56  ? 237 PHE D O   1 
ATOM 7052 C CB  . PHE D 1 237 ? 266.655 247.680 105.633 1.00 28.56  ? 237 PHE D CB  1 
ATOM 7053 C CG  . PHE D 1 237 ? 266.428 248.099 104.211 1.00 28.56  ? 237 PHE D CG  1 
ATOM 7054 C CD1 . PHE D 1 237 ? 265.183 248.486 103.788 1.00 28.56  ? 237 PHE D CD1 1 
ATOM 7055 C CD2 . PHE D 1 237 ? 267.453 248.094 103.305 1.00 28.56  ? 237 PHE D CD2 1 
ATOM 7056 C CE1 . PHE D 1 237 ? 264.976 248.856 102.500 1.00 28.56  ? 237 PHE D CE1 1 
ATOM 7057 C CE2 . PHE D 1 237 ? 267.243 248.452 102.025 1.00 28.56  ? 237 PHE D CE2 1 
ATOM 7058 C CZ  . PHE D 1 237 ? 266.008 248.839 101.622 1.00 28.56  ? 237 PHE D CZ  1 
ATOM 7059 N N   . GLY D 1 238 ? 268.449 244.975 106.020 1.00 15.05  ? 238 GLY D N   1 
ATOM 7060 C CA  . GLY D 1 238 ? 269.415 244.015 105.526 1.00 15.05  ? 238 GLY D CA  1 
ATOM 7061 C C   . GLY D 1 238 ? 268.767 242.703 105.155 1.00 15.05  ? 238 GLY D C   1 
ATOM 7062 O O   . GLY D 1 238 ? 268.898 242.255 104.023 1.00 15.05  ? 238 GLY D O   1 
ATOM 7063 N N   . VAL D 1 239 ? 267.991 242.129 106.085 1.00 9.88   ? 239 VAL D N   1 
ATOM 7064 C CA  . VAL D 1 239 ? 267.246 240.886 105.861 1.00 9.88   ? 239 VAL D CA  1 
ATOM 7065 C C   . VAL D 1 239 ? 266.312 241.012 104.669 1.00 9.88   ? 239 VAL D C   1 
ATOM 7066 O O   . VAL D 1 239 ? 266.246 240.114 103.826 1.00 9.88   ? 239 VAL D O   1 
ATOM 7067 C CB  . VAL D 1 239 ? 266.459 240.505 107.127 1.00 9.88   ? 239 VAL D CB  1 
ATOM 7068 C CG1 . VAL D 1 239 ? 265.665 239.273 106.899 1.00 9.88   ? 239 VAL D CG1 1 
ATOM 7069 C CG2 . VAL D 1 239 ? 267.371 240.291 108.281 1.00 9.88   ? 239 VAL D CG2 1 
ATOM 7070 N N   . TRP D 1 240 ? 265.620 242.149 104.553 1.00 13.22  ? 240 TRP D N   1 
ATOM 7071 C CA  . TRP D 1 240 ? 264.684 242.355 103.452 1.00 13.22  ? 240 TRP D CA  1 
ATOM 7072 C C   . TRP D 1 240 ? 265.392 242.406 102.105 1.00 13.22  ? 240 TRP D C   1 
ATOM 7073 O O   . TRP D 1 240 ? 264.922 241.819 101.130 1.00 13.22  ? 240 TRP D O   1 
ATOM 7074 C CB  . TRP D 1 240 ? 263.886 243.636 103.682 1.00 13.22  ? 240 TRP D CB  1 
ATOM 7075 C CG  . TRP D 1 240 ? 262.783 243.845 102.710 1.00 13.22  ? 240 TRP D CG  1 
ATOM 7076 C CD1 . TRP D 1 240 ? 261.551 243.296 102.755 1.00 13.22  ? 240 TRP D CD1 1 
ATOM 7077 C CD2 . TRP D 1 240 ? 262.814 244.664 101.542 1.00 13.22  ? 240 TRP D CD2 1 
ATOM 7078 N NE1 . TRP D 1 240 ? 260.809 243.715 101.691 1.00 13.22  ? 240 TRP D NE1 1 
ATOM 7079 C CE2 . TRP D 1 240 ? 261.569 244.554 100.928 1.00 13.22  ? 240 TRP D CE2 1 
ATOM 7080 C CE3 . TRP D 1 240 ? 263.778 245.481 100.959 1.00 13.22  ? 240 TRP D CE3 1 
ATOM 7081 C CZ2 . TRP D 1 240 ? 261.257 245.233 99.768  1.00 13.22  ? 240 TRP D CZ2 1 
ATOM 7082 C CZ3 . TRP D 1 240 ? 263.469 246.141 99.805  1.00 13.22  ? 240 TRP D CZ3 1 
ATOM 7083 C CH2 . TRP D 1 240 ? 262.226 246.016 99.220  1.00 13.22  ? 240 TRP D CH2 1 
ATOM 7084 N N   . ILE D 1 241 ? 266.540 243.073 102.033 1.00 14.65  ? 241 ILE D N   1 
ATOM 7085 C CA  . ILE D 1 241 ? 267.259 243.159 100.765 1.00 14.65  ? 241 ILE D CA  1 
ATOM 7086 C C   . ILE D 1 241 ? 268.105 241.923 100.476 1.00 14.65  ? 241 ILE D C   1 
ATOM 7087 O O   . ILE D 1 241 ? 268.561 241.755 99.338  1.00 14.65  ? 241 ILE D O   1 
ATOM 7088 C CB  . ILE D 1 241 ? 268.073 244.468 100.776 1.00 14.65  ? 241 ILE D CB  1 
ATOM 7089 C CG1 . ILE D 1 241 ? 268.331 244.980 99.365  1.00 14.65  ? 241 ILE D CG1 1 
ATOM 7090 C CG2 . ILE D 1 241 ? 269.369 244.307 101.523 1.00 14.65  ? 241 ILE D CG2 1 
ATOM 7091 C CD1 . ILE D 1 241 ? 267.146 245.577 98.726  1.00 14.65  ? 241 ILE D CD1 1 
ATOM 7092 N N   . ARG D 1 242 ? 268.315 241.037 101.462 1.00 16.15  ? 242 ARG D N   1 
ATOM 7093 C CA  . ARG D 1 242 ? 269.001 239.772 101.195 1.00 16.15  ? 242 ARG D CA  1 
ATOM 7094 C C   . ARG D 1 242 ? 268.157 238.866 100.315 1.00 16.15  ? 242 ARG D C   1 
ATOM 7095 O O   . ARG D 1 242 ? 268.670 238.261 99.370  1.00 16.15  ? 242 ARG D O   1 
ATOM 7096 C CB  . ARG D 1 242 ? 269.327 239.012 102.487 1.00 16.15  ? 242 ARG D CB  1 
ATOM 7097 C CG  . ARG D 1 242 ? 270.358 239.574 103.437 1.00 16.15  ? 242 ARG D CG  1 
ATOM 7098 C CD  . ARG D 1 242 ? 271.683 239.709 102.828 1.00 16.15  ? 242 ARG D CD  1 
ATOM 7099 N NE  . ARG D 1 242 ? 272.444 240.832 103.371 1.00 16.15  ? 242 ARG D NE  1 
ATOM 7100 C CZ  . ARG D 1 242 ? 272.882 241.859 102.647 1.00 16.15  ? 242 ARG D CZ  1 
ATOM 7101 N NH1 . ARG D 1 242 ? 272.640 241.917 101.346 1.00 16.15  ? 242 ARG D NH1 1 
ATOM 7102 N NH2 . ARG D 1 242 ? 273.583 242.819 103.217 1.00 16.15  ? 242 ARG D NH2 1 
ATOM 7103 N N   . THR D 1 243 ? 266.863 238.752 100.626 1.00 14.94  ? 243 THR D N   1 
ATOM 7104 C CA  . THR D 1 243 ? 266.019 237.724 100.034 1.00 14.94  ? 243 THR D CA  1 
ATOM 7105 C C   . THR D 1 243 ? 265.784 238.007 98.556  1.00 14.94  ? 243 THR D C   1 
ATOM 7106 O O   . THR D 1 243 ? 265.718 239.165 98.154  1.00 14.94  ? 243 THR D O   1 
ATOM 7107 C CB  . THR D 1 243 ? 264.679 237.634 100.752 1.00 14.94  ? 243 THR D CB  1 
ATOM 7108 O OG1 . THR D 1 243 ? 263.933 238.816 100.500 1.00 14.94  ? 243 THR D OG1 1 
ATOM 7109 C CG2 . THR D 1 243 ? 264.871 237.496 102.235 1.00 14.94  ? 243 THR D CG2 1 
ATOM 7110 N N   . PRO D 1 244 ? 265.699 236.972 97.729  1.00 16.54  ? 244 PRO D N   1 
ATOM 7111 C CA  . PRO D 1 244 ? 265.505 237.155 96.292  1.00 16.54  ? 244 PRO D CA  1 
ATOM 7112 C C   . PRO D 1 244 ? 264.153 237.770 95.985  1.00 16.54  ? 244 PRO D C   1 
ATOM 7113 O O   . PRO D 1 244 ? 263.267 237.760 96.850  1.00 16.54  ? 244 PRO D O   1 
ATOM 7114 C CB  . PRO D 1 244 ? 265.612 235.717 95.767  1.00 16.54  ? 244 PRO D CB  1 
ATOM 7115 C CG  . PRO D 1 244 ? 266.564 235.107 96.697  1.00 16.54  ? 244 PRO D CG  1 
ATOM 7116 C CD  . PRO D 1 244 ? 266.151 235.606 98.028  1.00 16.54  ? 244 PRO D CD  1 
ATOM 7117 N N   . PRO D 1 245 ? 263.964 238.341 94.787  1.00 28.56  ? 245 PRO D N   1 
ATOM 7118 C CA  . PRO D 1 245 ? 262.711 239.063 94.505  1.00 28.56  ? 245 PRO D CA  1 
ATOM 7119 C C   . PRO D 1 245 ? 261.463 238.208 94.535  1.00 28.56  ? 245 PRO D C   1 
ATOM 7120 O O   . PRO D 1 245 ? 260.377 238.737 94.788  1.00 28.56  ? 245 PRO D O   1 
ATOM 7121 C CB  . PRO D 1 245 ? 262.943 239.624 93.098  1.00 28.56  ? 245 PRO D CB  1 
ATOM 7122 C CG  . PRO D 1 245 ? 264.387 239.672 92.938  1.00 28.56  ? 245 PRO D CG  1 
ATOM 7123 C CD  . PRO D 1 245 ? 264.945 238.537 93.706  1.00 28.56  ? 245 PRO D CD  1 
ATOM 7124 N N   . ALA D 1 246 ? 261.585 236.903 94.297  1.00 28.56  ? 246 ALA D N   1 
ATOM 7125 C CA  . ALA D 1 246 ? 260.428 236.021 94.299  1.00 28.56  ? 246 ALA D CA  1 
ATOM 7126 C C   . ALA D 1 246 ? 259.845 235.812 95.687  1.00 28.56  ? 246 ALA D C   1 
ATOM 7127 O O   . ALA D 1 246 ? 258.667 235.471 95.799  1.00 28.56  ? 246 ALA D O   1 
ATOM 7128 C CB  . ALA D 1 246 ? 260.807 234.678 93.695  1.00 28.56  ? 246 ALA D CB  1 
ATOM 7129 N N   . TYR D 1 247 ? 260.627 236.014 96.741  1.00 14.43  ? 247 TYR D N   1 
ATOM 7130 C CA  . TYR D 1 247 ? 260.177 235.740 98.095  1.00 14.43  ? 247 TYR D CA  1 
ATOM 7131 C C   . TYR D 1 247 ? 260.174 236.970 98.974  1.00 14.43  ? 247 TYR D C   1 
ATOM 7132 O O   . TYR D 1 247 ? 259.912 236.852 100.175 1.00 14.43  ? 247 TYR D O   1 
ATOM 7133 C CB  . TYR D 1 247 ? 261.051 234.657 98.733  1.00 14.43  ? 247 TYR D CB  1 
ATOM 7134 C CG  . TYR D 1 247 ? 261.005 233.385 97.943  1.00 14.43  ? 247 TYR D CG  1 
ATOM 7135 C CD1 . TYR D 1 247 ? 259.942 232.510 98.083  1.00 14.43  ? 247 TYR D CD1 1 
ATOM 7136 C CD2 . TYR D 1 247 ? 261.990 233.083 97.022  1.00 14.43  ? 247 TYR D CD2 1 
ATOM 7137 C CE1 . TYR D 1 247 ? 259.870 231.369 97.344  1.00 14.43  ? 247 TYR D CE1 1 
ATOM 7138 C CE2 . TYR D 1 247 ? 261.926 231.945 96.282  1.00 14.43  ? 247 TYR D CE2 1 
ATOM 7139 C CZ  . TYR D 1 247 ? 260.861 231.091 96.449  1.00 14.43  ? 247 TYR D CZ  1 
ATOM 7140 O OH  . TYR D 1 247 ? 260.781 229.940 95.713  1.00 14.43  ? 247 TYR D OH  1 
ATOM 7141 N N   . ARG D 1 248 ? 260.442 238.133 98.412  1.00 13.50  ? 248 ARG D N   1 
ATOM 7142 C CA  . ARG D 1 248 ? 260.527 239.368 99.174  1.00 13.50  ? 248 ARG D CA  1 
ATOM 7143 C C   . ARG D 1 248 ? 259.134 239.930 99.414  1.00 13.50  ? 248 ARG D C   1 
ATOM 7144 O O   . ARG D 1 248 ? 258.350 240.035 98.468  1.00 13.50  ? 248 ARG D O   1 
ATOM 7145 C CB  . ARG D 1 248 ? 261.367 240.377 98.423  1.00 13.50  ? 248 ARG D CB  1 
ATOM 7146 C CG  . ARG D 1 248 ? 262.122 241.309 99.306  1.00 13.50  ? 248 ARG D CG  1 
ATOM 7147 C CD  . ARG D 1 248 ? 262.859 242.323 98.490  1.00 13.50  ? 248 ARG D CD  1 
ATOM 7148 N NE  . ARG D 1 248 ? 264.104 241.814 97.955  1.00 13.50  ? 248 ARG D NE  1 
ATOM 7149 C CZ  . ARG D 1 248 ? 264.642 242.254 96.831  1.00 13.50  ? 248 ARG D CZ  1 
ATOM 7150 N NH1 . ARG D 1 248 ? 265.780 241.755 96.395  1.00 13.50  ? 248 ARG D NH1 1 
ATOM 7151 N NH2 . ARG D 1 248 ? 264.031 243.191 96.138  1.00 13.50  ? 248 ARG D NH2 1 
ATOM 7152 N N   . PRO D 1 249 ? 258.788 240.282 100.652 1.00 12.82  ? 249 PRO D N   1 
ATOM 7153 C CA  . PRO D 1 249 ? 257.498 240.905 100.895 1.00 12.82  ? 249 PRO D CA  1 
ATOM 7154 C C   . PRO D 1 249 ? 257.447 242.282 100.266 1.00 12.82  ? 249 PRO D C   1 
ATOM 7155 O O   . PRO D 1 249 ? 258.478 242.965 100.158 1.00 12.82  ? 249 PRO D O   1 
ATOM 7156 C CB  . PRO D 1 249 ? 257.428 240.982 102.431 1.00 12.82  ? 249 PRO D CB  1 
ATOM 7157 C CG  . PRO D 1 249 ? 258.400 240.028 102.903 1.00 12.82  ? 249 PRO D CG  1 
ATOM 7158 C CD  . PRO D 1 249 ? 259.489 239.980 101.902 1.00 12.82  ? 249 PRO D CD  1 
ATOM 7159 N N   . PRO D 1 250 ? 256.270 242.736 99.822  1.00 28.56  ? 250 PRO D N   1 
ATOM 7160 C CA  . PRO D 1 250 ? 256.219 243.929 98.972  1.00 28.56  ? 250 PRO D CA  1 
ATOM 7161 C C   . PRO D 1 250 ? 256.391 245.234 99.711  1.00 28.56  ? 250 PRO D C   1 
ATOM 7162 O O   . PRO D 1 250 ? 256.665 246.252 99.066  1.00 28.56  ? 250 PRO D O   1 
ATOM 7163 C CB  . PRO D 1 250 ? 254.829 243.844 98.352  1.00 28.56  ? 250 PRO D CB  1 
ATOM 7164 C CG  . PRO D 1 250 ? 254.032 243.206 99.409  1.00 28.56  ? 250 PRO D CG  1 
ATOM 7165 C CD  . PRO D 1 250 ? 254.921 242.225 100.100 1.00 28.56  ? 250 PRO D CD  1 
ATOM 7166 N N   . ASN D 1 251 ? 256.251 245.256 101.021 1.00 28.56  ? 251 ASN D N   1 
ATOM 7167 C CA  . ASN D 1 251 ? 256.469 246.478 101.773 1.00 28.56  ? 251 ASN D CA  1 
ATOM 7168 C C   . ASN D 1 251 ? 257.771 246.350 102.542 1.00 28.56  ? 251 ASN D C   1 
ATOM 7169 O O   . ASN D 1 251 ? 257.863 245.582 103.503 1.00 28.56  ? 251 ASN D O   1 
ATOM 7170 C CB  . ASN D 1 251 ? 255.296 246.799 102.694 1.00 28.56  ? 251 ASN D CB  1 
ATOM 7171 C CG  . ASN D 1 251 ? 254.750 245.600 103.398 1.00 28.56  ? 251 ASN D CG  1 
ATOM 7172 O OD1 . ASN D 1 251 ? 255.237 244.486 103.234 1.00 28.56  ? 251 ASN D OD1 1 
ATOM 7173 N ND2 . ASN D 1 251 ? 253.717 245.818 104.196 1.00 28.56  ? 251 ASN D ND2 1 
ATOM 7174 N N   . ALA D 1 252 ? 258.769 247.117 102.110 1.00 12.75  ? 252 ALA D N   1 
ATOM 7175 C CA  . ALA D 1 252 ? 260.050 247.219 102.777 1.00 12.75  ? 252 ALA D CA  1 
ATOM 7176 C C   . ALA D 1 252 ? 259.878 247.757 104.189 1.00 12.75  ? 252 ALA D C   1 
ATOM 7177 O O   . ALA D 1 252 ? 258.872 248.391 104.495 1.00 12.75  ? 252 ALA D O   1 
ATOM 7178 C CB  . ALA D 1 252 ? 260.958 248.140 101.980 1.00 12.75  ? 252 ALA D CB  1 
ATOM 7179 N N   . PRO D 1 253 ? 260.821 247.490 105.086 1.00 12.37  ? 253 PRO D N   1 
ATOM 7180 C CA  . PRO D 1 253 ? 260.772 248.162 106.383 1.00 12.37  ? 253 PRO D CA  1 
ATOM 7181 C C   . PRO D 1 253 ? 261.061 249.642 106.214 1.00 12.37  ? 253 PRO D C   1 
ATOM 7182 O O   . PRO D 1 253 ? 261.795 250.063 105.317 1.00 12.37  ? 253 PRO D O   1 
ATOM 7183 C CB  . PRO D 1 253 ? 261.860 247.457 107.194 1.00 12.37  ? 253 PRO D CB  1 
ATOM 7184 C CG  . PRO D 1 253 ? 262.727 246.887 106.207 1.00 12.37  ? 253 PRO D CG  1 
ATOM 7185 C CD  . PRO D 1 253 ? 261.890 246.485 105.065 1.00 12.37  ? 253 PRO D CD  1 
ATOM 7186 N N   . ILE D 1 254 ? 260.435 250.444 107.062 1.00 12.41  ? 254 ILE D N   1 
ATOM 7187 C CA  . ILE D 1 254 ? 260.542 251.885 106.937 1.00 12.41  ? 254 ILE D CA  1 
ATOM 7188 C C   . ILE D 1 254 ? 260.560 252.468 108.335 1.00 12.41  ? 254 ILE D C   1 
ATOM 7189 O O   . ILE D 1 254 ? 260.113 251.841 109.296 1.00 12.41  ? 254 ILE D O   1 
ATOM 7190 C CB  . ILE D 1 254 ? 259.399 252.451 106.064 1.00 12.41  ? 254 ILE D CB  1 
ATOM 7191 C CG1 . ILE D 1 254 ? 259.801 253.773 105.418 1.00 12.41  ? 254 ILE D CG1 1 
ATOM 7192 C CG2 . ILE D 1 254 ? 258.129 252.600 106.854 1.00 12.41  ? 254 ILE D CG2 1 
ATOM 7193 C CD1 . ILE D 1 254 ? 258.794 254.289 104.460 1.00 12.41  ? 254 ILE D CD1 1 
ATOM 7194 N N   . LEU D 1 255 ? 261.144 253.646 108.451 1.00 12.31  ? 255 LEU D N   1 
ATOM 7195 C CA  . LEU D 1 255 ? 261.217 254.345 109.715 1.00 12.31  ? 255 LEU D CA  1 
ATOM 7196 C C   . LEU D 1 255 ? 259.972 255.208 109.843 1.00 12.31  ? 255 LEU D C   1 
ATOM 7197 O O   . LEU D 1 255 ? 259.684 256.024 108.964 1.00 12.31  ? 255 LEU D O   1 
ATOM 7198 C CB  . LEU D 1 255 ? 262.478 255.195 109.781 1.00 12.31  ? 255 LEU D CB  1 
ATOM 7199 C CG  . LEU D 1 255 ? 263.833 254.535 109.943 1.00 12.31  ? 255 LEU D CG  1 
ATOM 7200 C CD1 . LEU D 1 255 ? 264.864 255.432 109.341 1.00 12.31  ? 255 LEU D CD1 1 
ATOM 7201 C CD2 . LEU D 1 255 ? 264.118 254.311 111.391 1.00 12.31  ? 255 LEU D CD2 1 
ATOM 7202 N N   . SER D 1 256 ? 259.224 255.014 110.921 1.00 12.57  ? 256 SER D N   1 
ATOM 7203 C CA  . SER D 1 256 ? 258.009 255.778 111.139 1.00 12.57  ? 256 SER D CA  1 
ATOM 7204 C C   . SER D 1 256 ? 257.729 255.793 112.627 1.00 12.57  ? 256 SER D C   1 
ATOM 7205 O O   . SER D 1 256 ? 258.334 255.052 113.401 1.00 12.57  ? 256 SER D O   1 
ATOM 7206 C CB  . SER D 1 256 ? 256.830 255.197 110.363 1.00 12.57  ? 256 SER D CB  1 
ATOM 7207 O OG  . SER D 1 256 ? 256.874 255.600 109.007 1.00 12.57  ? 256 SER D OG  1 
ATOM 7208 N N   . THR D 1 257 ? 256.810 256.665 113.017 1.00 16.60  ? 257 THR D N   1 
ATOM 7209 C CA  . THR D 1 257 ? 256.408 256.825 114.406 1.00 16.60  ? 257 THR D CA  1 
ATOM 7210 C C   . THR D 1 257 ? 254.901 256.662 114.563 1.00 16.60  ? 257 THR D C   1 
ATOM 7211 O O   . THR D 1 257 ? 254.304 257.203 115.493 1.00 16.60  ? 257 THR D O   1 
ATOM 7212 C CB  . THR D 1 257 ? 256.860 258.182 114.938 1.00 16.60  ? 257 THR D CB  1 
ATOM 7213 O OG1 . THR D 1 257 ? 256.665 259.181 113.930 1.00 16.60  ? 257 THR D OG1 1 
ATOM 7214 C CG2 . THR D 1 257 ? 258.325 258.137 115.312 1.00 16.60  ? 257 THR D CG2 1 
ATOM 7215 N N   . LEU D 1 258 ? 254.278 255.915 113.661 1.00 14.68  ? 258 LEU D N   1 
ATOM 7216 C CA  . LEU D 1 258 ? 252.833 255.816 113.625 1.00 14.68  ? 258 LEU D CA  1 
ATOM 7217 C C   . LEU D 1 258 ? 252.342 254.386 113.810 1.00 14.68  ? 258 LEU D C   1 
ATOM 7218 O O   . LEU D 1 258 ? 251.148 254.150 114.014 1.00 14.68  ? 258 LEU D O   1 
ATOM 7219 C CB  . LEU D 1 258 ? 252.309 256.370 112.308 1.00 14.68  ? 258 LEU D CB  1 
ATOM 7220 C CG  . LEU D 1 258 ? 252.803 257.756 111.906 1.00 14.68  ? 258 LEU D CG  1 
ATOM 7221 C CD1 . LEU D 1 258 ? 252.365 258.084 110.495 1.00 14.68  ? 258 LEU D CD1 1 
ATOM 7222 C CD2 . LEU D 1 258 ? 252.308 258.795 112.887 1.00 14.68  ? 258 LEU D CD2 1 
# 
