data_9FUP
# 
_entry.id   9FUP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FUP         pdb_00009fup 10.2210/pdb9fup/pdb 
WWPDB D_1292139738 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FUP 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'Same citation' 9FTU unspecified 
PDB 'Same citation' 9FTS unspecified 
PDB 'Same citation' 9FTV unspecified 
PDB 'Same citation' 9FTX unspecified 
PDB 'Same citation' 9FTY unspecified 
PDB 'Same citation' 9FU1 unspecified 
PDB 'Same citation' 9FUD unspecified 
PDB 'Same citation' 9FUE unspecified 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              daniele.de_sanctis@esrf.fr 
_pdbx_contact_author.name_first         Daniele 
_pdbx_contact_author.name_last          'de Sanctis' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0391-8290 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Orlans, J.'     1 0000-0002-6933-2287 
'Rose, S.L.'     2 0000-0003-4824-4066 
'Ferguson, G.'   3 0000-0003-2551-5994 
'Lebon, G.'      4 0000-0003-1162-5148 
'Basu, S.'       5 0000-0001-6484-8236 
'de Sanctis, D.' 6 0000-0003-0391-8290 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Commun Chem' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2399-3669 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            8 
_citation.language                  ? 
_citation.page_first                6 
_citation.page_last                 6 
_citation.title                     
'Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s42004-024-01404-y 
_citation.pdbx_database_id_PubMed   39775172 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Orlans, J.'        1  ?                   
primary 'Rose, S.L.'        2  0000-0003-4824-4066 
primary 'Ferguson, G.'      3  0000-0003-2551-5994 
primary 'Oscarsson, M.'     4  ?                   
primary 'Homs Puron, A.'    5  ?                   
primary 'Beteva, A.'        6  ?                   
primary 'Debionne, S.'      7  ?                   
primary 'Theveneau, P.'     8  ?                   
primary 'Coquelle, N.'      9  ?                   
primary 'Kieffer, J.'       10 0000-0002-0730-6577 
primary 'Busca, P.'         11 ?                   
primary 'Sinoir, J.'        12 ?                   
primary 'Armijo, V.'        13 0009-0006-3243-8391 
primary 'Lopez Marrero, M.' 14 ?                   
primary 'Felisaz, F.'       15 ?                   
primary 'Papp, G.'          16 0000-0002-5702-843X 
primary 'Gonzalez, H.'      17 ?                   
primary 'Caserotto, H.'     18 ?                   
primary 'Dobias, F.'        19 ?                   
primary 'Gigmes, J.'        20 ?                   
primary 'Lebon, G.'         21 0000-0003-1162-5148 
primary 'Basu, S.'          22 0000-0001-6484-8236 
primary 'de Sanctis, D.'    23 0000-0003-0391-8290 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Adenosine receptor A2a,Soluble cytochrome b562'                                  46615.297 1  ? ? ? ? 
2 non-polymer syn 'SODIUM ION'                                                                      22.990    1  ? ? ? ? 
3 non-polymer syn CHOLESTEROL                                                                       386.654   3  ? ? ? ? 
4 non-polymer syn 'OLEIC ACID'                                                                      282.461   11 ? ? ? ? 
5 non-polymer syn '(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  356.540   2  ? ? ? ? 
6 non-polymer syn '(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  356.540   2  ? ? ? ? 
7 non-polymer syn '8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione' 384.429   1  ? ? ? ? 
8 water       nat water                                                                             18.015    42 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Cytochrome b-562' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DYKDDDDGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFC
AACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKE
GKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNA
AQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQ
KYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREF
RQTFRKIIRSHVLRQQEPFKAAA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DYKDDDDGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFC
AACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKE
GKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNA
AQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQ
KYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREF
RQTFRKIIRSHVLRQQEPFKAAA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SODIUM ION'                                                                      NA  
3 CHOLESTEROL                                                                       CLR 
4 'OLEIC ACID'                                                                      OLA 
5 '(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  OLB 
6 '(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  OLC 
7 '8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione' JQ9 
8 water                                                                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   TYR n 
1 3   LYS n 
1 4   ASP n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   GLY n 
1 9   ALA n 
1 10  PRO n 
1 11  PRO n 
1 12  ILE n 
1 13  MET n 
1 14  GLY n 
1 15  SER n 
1 16  SER n 
1 17  VAL n 
1 18  TYR n 
1 19  ILE n 
1 20  THR n 
1 21  VAL n 
1 22  GLU n 
1 23  LEU n 
1 24  ALA n 
1 25  ILE n 
1 26  ALA n 
1 27  VAL n 
1 28  LEU n 
1 29  ALA n 
1 30  ILE n 
1 31  LEU n 
1 32  GLY n 
1 33  ASN n 
1 34  VAL n 
1 35  LEU n 
1 36  VAL n 
1 37  CYS n 
1 38  TRP n 
1 39  ALA n 
1 40  VAL n 
1 41  TRP n 
1 42  LEU n 
1 43  ASN n 
1 44  SER n 
1 45  ASN n 
1 46  LEU n 
1 47  GLN n 
1 48  ASN n 
1 49  VAL n 
1 50  THR n 
1 51  ASN n 
1 52  TYR n 
1 53  PHE n 
1 54  VAL n 
1 55  VAL n 
1 56  SER n 
1 57  LEU n 
1 58  ALA n 
1 59  ALA n 
1 60  ALA n 
1 61  ASP n 
1 62  ILE n 
1 63  LEU n 
1 64  VAL n 
1 65  GLY n 
1 66  VAL n 
1 67  LEU n 
1 68  ALA n 
1 69  ILE n 
1 70  PRO n 
1 71  PHE n 
1 72  ALA n 
1 73  ILE n 
1 74  THR n 
1 75  ILE n 
1 76  SER n 
1 77  THR n 
1 78  GLY n 
1 79  PHE n 
1 80  CYS n 
1 81  ALA n 
1 82  ALA n 
1 83  CYS n 
1 84  HIS n 
1 85  GLY n 
1 86  CYS n 
1 87  LEU n 
1 88  PHE n 
1 89  ILE n 
1 90  ALA n 
1 91  CYS n 
1 92  PHE n 
1 93  VAL n 
1 94  LEU n 
1 95  VAL n 
1 96  LEU n 
1 97  ALA n 
1 98  GLN n 
1 99  SER n 
1 100 SER n 
1 101 ILE n 
1 102 PHE n 
1 103 SER n 
1 104 LEU n 
1 105 LEU n 
1 106 ALA n 
1 107 ILE n 
1 108 ALA n 
1 109 ILE n 
1 110 ASP n 
1 111 ARG n 
1 112 TYR n 
1 113 ILE n 
1 114 ALA n 
1 115 ILE n 
1 116 ALA n 
1 117 ILE n 
1 118 PRO n 
1 119 LEU n 
1 120 ARG n 
1 121 TYR n 
1 122 ASN n 
1 123 GLY n 
1 124 LEU n 
1 125 VAL n 
1 126 THR n 
1 127 GLY n 
1 128 THR n 
1 129 ARG n 
1 130 ALA n 
1 131 ALA n 
1 132 GLY n 
1 133 ILE n 
1 134 ILE n 
1 135 ALA n 
1 136 ILE n 
1 137 CYS n 
1 138 TRP n 
1 139 VAL n 
1 140 LEU n 
1 141 SER n 
1 142 PHE n 
1 143 ALA n 
1 144 ILE n 
1 145 GLY n 
1 146 LEU n 
1 147 THR n 
1 148 PRO n 
1 149 MET n 
1 150 LEU n 
1 151 GLY n 
1 152 TRP n 
1 153 ASN n 
1 154 ASN n 
1 155 CYS n 
1 156 GLY n 
1 157 GLN n 
1 158 PRO n 
1 159 LYS n 
1 160 GLU n 
1 161 GLY n 
1 162 LYS n 
1 163 ALA n 
1 164 HIS n 
1 165 SER n 
1 166 GLN n 
1 167 GLY n 
1 168 CYS n 
1 169 GLY n 
1 170 GLU n 
1 171 GLY n 
1 172 GLN n 
1 173 VAL n 
1 174 ALA n 
1 175 CYS n 
1 176 LEU n 
1 177 PHE n 
1 178 GLU n 
1 179 ASP n 
1 180 VAL n 
1 181 VAL n 
1 182 PRO n 
1 183 MET n 
1 184 ASN n 
1 185 TYR n 
1 186 MET n 
1 187 VAL n 
1 188 TYR n 
1 189 PHE n 
1 190 ASN n 
1 191 PHE n 
1 192 PHE n 
1 193 ALA n 
1 194 CYS n 
1 195 VAL n 
1 196 LEU n 
1 197 VAL n 
1 198 PRO n 
1 199 LEU n 
1 200 LEU n 
1 201 LEU n 
1 202 MET n 
1 203 LEU n 
1 204 GLY n 
1 205 VAL n 
1 206 TYR n 
1 207 LEU n 
1 208 ARG n 
1 209 ILE n 
1 210 PHE n 
1 211 ALA n 
1 212 ALA n 
1 213 ALA n 
1 214 ARG n 
1 215 ARG n 
1 216 GLN n 
1 217 LEU n 
1 218 ALA n 
1 219 ASP n 
1 220 LEU n 
1 221 GLU n 
1 222 ASP n 
1 223 ASN n 
1 224 TRP n 
1 225 GLU n 
1 226 THR n 
1 227 LEU n 
1 228 ASN n 
1 229 ASP n 
1 230 ASN n 
1 231 LEU n 
1 232 LYS n 
1 233 VAL n 
1 234 ILE n 
1 235 GLU n 
1 236 LYS n 
1 237 ALA n 
1 238 ASP n 
1 239 ASN n 
1 240 ALA n 
1 241 ALA n 
1 242 GLN n 
1 243 VAL n 
1 244 LYS n 
1 245 ASP n 
1 246 ALA n 
1 247 LEU n 
1 248 THR n 
1 249 LYS n 
1 250 MET n 
1 251 ARG n 
1 252 ALA n 
1 253 ALA n 
1 254 ALA n 
1 255 LEU n 
1 256 ASP n 
1 257 ALA n 
1 258 GLN n 
1 259 LYS n 
1 260 ALA n 
1 261 THR n 
1 262 PRO n 
1 263 PRO n 
1 264 LYS n 
1 265 LEU n 
1 266 GLU n 
1 267 ASP n 
1 268 LYS n 
1 269 SER n 
1 270 PRO n 
1 271 ASP n 
1 272 SER n 
1 273 PRO n 
1 274 GLU n 
1 275 MET n 
1 276 LYS n 
1 277 ASP n 
1 278 PHE n 
1 279 ARG n 
1 280 HIS n 
1 281 GLY n 
1 282 PHE n 
1 283 ASP n 
1 284 ILE n 
1 285 LEU n 
1 286 VAL n 
1 287 GLY n 
1 288 GLN n 
1 289 ILE n 
1 290 ASP n 
1 291 ASP n 
1 292 ALA n 
1 293 LEU n 
1 294 LYS n 
1 295 LEU n 
1 296 ALA n 
1 297 ASN n 
1 298 GLU n 
1 299 GLY n 
1 300 LYS n 
1 301 VAL n 
1 302 LYS n 
1 303 GLU n 
1 304 ALA n 
1 305 GLN n 
1 306 ALA n 
1 307 ALA n 
1 308 ALA n 
1 309 GLU n 
1 310 GLN n 
1 311 LEU n 
1 312 LYS n 
1 313 THR n 
1 314 THR n 
1 315 ARG n 
1 316 ASN n 
1 317 ALA n 
1 318 TYR n 
1 319 ILE n 
1 320 GLN n 
1 321 LYS n 
1 322 TYR n 
1 323 LEU n 
1 324 GLU n 
1 325 ARG n 
1 326 ALA n 
1 327 ARG n 
1 328 SER n 
1 329 THR n 
1 330 LEU n 
1 331 GLN n 
1 332 LYS n 
1 333 GLU n 
1 334 VAL n 
1 335 HIS n 
1 336 ALA n 
1 337 ALA n 
1 338 LYS n 
1 339 SER n 
1 340 ALA n 
1 341 ALA n 
1 342 ILE n 
1 343 ILE n 
1 344 ALA n 
1 345 GLY n 
1 346 LEU n 
1 347 PHE n 
1 348 ALA n 
1 349 LEU n 
1 350 CYS n 
1 351 TRP n 
1 352 LEU n 
1 353 PRO n 
1 354 LEU n 
1 355 HIS n 
1 356 ILE n 
1 357 ILE n 
1 358 ASN n 
1 359 CYS n 
1 360 PHE n 
1 361 THR n 
1 362 PHE n 
1 363 PHE n 
1 364 CYS n 
1 365 PRO n 
1 366 ASP n 
1 367 CYS n 
1 368 SER n 
1 369 HIS n 
1 370 ALA n 
1 371 PRO n 
1 372 LEU n 
1 373 TRP n 
1 374 LEU n 
1 375 MET n 
1 376 TYR n 
1 377 LEU n 
1 378 ALA n 
1 379 ILE n 
1 380 VAL n 
1 381 LEU n 
1 382 ALA n 
1 383 HIS n 
1 384 THR n 
1 385 ASN n 
1 386 SER n 
1 387 VAL n 
1 388 VAL n 
1 389 ASN n 
1 390 PRO n 
1 391 PHE n 
1 392 ILE n 
1 393 TYR n 
1 394 ALA n 
1 395 TYR n 
1 396 ARG n 
1 397 ILE n 
1 398 ARG n 
1 399 GLU n 
1 400 PHE n 
1 401 ARG n 
1 402 GLN n 
1 403 THR n 
1 404 PHE n 
1 405 ARG n 
1 406 LYS n 
1 407 ILE n 
1 408 ILE n 
1 409 ARG n 
1 410 SER n 
1 411 HIS n 
1 412 VAL n 
1 413 LEU n 
1 414 ARG n 
1 415 GLN n 
1 416 GLN n 
1 417 GLU n 
1 418 PRO n 
1 419 PHE n 
1 420 LYS n 
1 421 ALA n 
1 422 ALA n 
1 423 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   217 human ? 'ADORA2A, ADORA2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 218 323 human ? cybC              ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 324 423 human ? 'ADORA2A, ADORA2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                           ?                   
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                          ?                   
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                        ?                   
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                   ?                   
'C4 H7 N O4'     133.103 
CLR non-polymer         . CHOLESTEROL                                                                       ?                   
'C27 H46 O'      386.654 
CYS 'L-peptide linking' y CYSTEINE                                                                          ?                   
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                         ?                   
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                   ?                   
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                           ?                   
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                         ?                   
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                                             ?                   
'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                        ?                   
'C6 H13 N O2'    131.173 
JQ9 non-polymer         . '8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione' istradefylline      
'C20 H24 N4 O4'  384.429 
LEU 'L-peptide linking' y LEUCINE                                                                           ?                   
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                            ?                   
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                        ?                   
'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'                                                                      ?                   
'Na 1'           22.990  
OLA non-polymer         . 'OLEIC ACID'                                                                      ?                   
'C18 H34 O2'     282.461 
OLB non-polymer         . '(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  ?                   
'C21 H40 O4'     356.540 
OLC non-polymer         . '(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate'                                  1-Oleoyl-R-glycerol 
'C21 H40 O4'     356.540 
PHE 'L-peptide linking' y PHENYLALANINE                                                                     ?                   
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                                           ?                   
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                            ?                   
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                         ?                   
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                        ?                   
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                          ?                   
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                            ?                   
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   -8   ?    ?   ?   A . n 
A 1 2   TYR 2   -7   ?    ?   ?   A . n 
A 1 3   LYS 3   -6   ?    ?   ?   A . n 
A 1 4   ASP 4   -5   ?    ?   ?   A . n 
A 1 5   ASP 5   -4   ?    ?   ?   A . n 
A 1 6   ASP 6   -3   ?    ?   ?   A . n 
A 1 7   ASP 7   -2   ?    ?   ?   A . n 
A 1 8   GLY 8   -1   ?    ?   ?   A . n 
A 1 9   ALA 9   0    0    ALA ALA A . n 
A 1 10  PRO 10  1    1    PRO PRO A . n 
A 1 11  PRO 11  2    2    PRO PRO A . n 
A 1 12  ILE 12  3    3    ILE ILE A . n 
A 1 13  MET 13  4    4    MET MET A . n 
A 1 14  GLY 14  5    5    GLY GLY A . n 
A 1 15  SER 15  6    6    SER SER A . n 
A 1 16  SER 16  7    7    SER SER A . n 
A 1 17  VAL 17  8    8    VAL VAL A . n 
A 1 18  TYR 18  9    9    TYR TYR A . n 
A 1 19  ILE 19  10   10   ILE ILE A . n 
A 1 20  THR 20  11   11   THR THR A . n 
A 1 21  VAL 21  12   12   VAL VAL A . n 
A 1 22  GLU 22  13   13   GLU GLU A . n 
A 1 23  LEU 23  14   14   LEU LEU A . n 
A 1 24  ALA 24  15   15   ALA ALA A . n 
A 1 25  ILE 25  16   16   ILE ILE A . n 
A 1 26  ALA 26  17   17   ALA ALA A . n 
A 1 27  VAL 27  18   18   VAL VAL A . n 
A 1 28  LEU 28  19   19   LEU LEU A . n 
A 1 29  ALA 29  20   20   ALA ALA A . n 
A 1 30  ILE 30  21   21   ILE ILE A . n 
A 1 31  LEU 31  22   22   LEU LEU A . n 
A 1 32  GLY 32  23   23   GLY GLY A . n 
A 1 33  ASN 33  24   24   ASN ASN A . n 
A 1 34  VAL 34  25   25   VAL VAL A . n 
A 1 35  LEU 35  26   26   LEU LEU A . n 
A 1 36  VAL 36  27   27   VAL VAL A . n 
A 1 37  CYS 37  28   28   CYS CYS A . n 
A 1 38  TRP 38  29   29   TRP TRP A . n 
A 1 39  ALA 39  30   30   ALA ALA A . n 
A 1 40  VAL 40  31   31   VAL VAL A . n 
A 1 41  TRP 41  32   32   TRP TRP A . n 
A 1 42  LEU 42  33   33   LEU LEU A . n 
A 1 43  ASN 43  34   34   ASN ASN A . n 
A 1 44  SER 44  35   35   SER SER A . n 
A 1 45  ASN 45  36   36   ASN ASN A . n 
A 1 46  LEU 46  37   37   LEU LEU A . n 
A 1 47  GLN 47  38   38   GLN GLN A . n 
A 1 48  ASN 48  39   39   ASN ASN A . n 
A 1 49  VAL 49  40   40   VAL VAL A . n 
A 1 50  THR 50  41   41   THR THR A . n 
A 1 51  ASN 51  42   42   ASN ASN A . n 
A 1 52  TYR 52  43   43   TYR TYR A . n 
A 1 53  PHE 53  44   44   PHE PHE A . n 
A 1 54  VAL 54  45   45   VAL VAL A . n 
A 1 55  VAL 55  46   46   VAL VAL A . n 
A 1 56  SER 56  47   47   SER SER A . n 
A 1 57  LEU 57  48   48   LEU LEU A . n 
A 1 58  ALA 58  49   49   ALA ALA A . n 
A 1 59  ALA 59  50   50   ALA ALA A . n 
A 1 60  ALA 60  51   51   ALA ALA A . n 
A 1 61  ASP 61  52   52   ASP ASP A . n 
A 1 62  ILE 62  53   53   ILE ILE A . n 
A 1 63  LEU 63  54   54   LEU LEU A . n 
A 1 64  VAL 64  55   55   VAL VAL A . n 
A 1 65  GLY 65  56   56   GLY GLY A . n 
A 1 66  VAL 66  57   57   VAL VAL A . n 
A 1 67  LEU 67  58   58   LEU LEU A . n 
A 1 68  ALA 68  59   59   ALA ALA A . n 
A 1 69  ILE 69  60   60   ILE ILE A . n 
A 1 70  PRO 70  61   61   PRO PRO A . n 
A 1 71  PHE 71  62   62   PHE PHE A . n 
A 1 72  ALA 72  63   63   ALA ALA A . n 
A 1 73  ILE 73  64   64   ILE ILE A . n 
A 1 74  THR 74  65   65   THR THR A . n 
A 1 75  ILE 75  66   66   ILE ILE A . n 
A 1 76  SER 76  67   67   SER SER A . n 
A 1 77  THR 77  68   68   THR THR A . n 
A 1 78  GLY 78  69   69   GLY GLY A . n 
A 1 79  PHE 79  70   70   PHE PHE A . n 
A 1 80  CYS 80  71   71   CYS CYS A . n 
A 1 81  ALA 81  72   72   ALA ALA A . n 
A 1 82  ALA 82  73   73   ALA ALA A . n 
A 1 83  CYS 83  74   74   CYS CYS A . n 
A 1 84  HIS 84  75   75   HIS HIS A . n 
A 1 85  GLY 85  76   76   GLY GLY A . n 
A 1 86  CYS 86  77   77   CYS CYS A . n 
A 1 87  LEU 87  78   78   LEU LEU A . n 
A 1 88  PHE 88  79   79   PHE PHE A . n 
A 1 89  ILE 89  80   80   ILE ILE A . n 
A 1 90  ALA 90  81   81   ALA ALA A . n 
A 1 91  CYS 91  82   82   CYS CYS A . n 
A 1 92  PHE 92  83   83   PHE PHE A . n 
A 1 93  VAL 93  84   84   VAL VAL A . n 
A 1 94  LEU 94  85   85   LEU LEU A . n 
A 1 95  VAL 95  86   86   VAL VAL A . n 
A 1 96  LEU 96  87   87   LEU LEU A . n 
A 1 97  ALA 97  88   88   ALA ALA A . n 
A 1 98  GLN 98  89   89   GLN GLN A . n 
A 1 99  SER 99  90   90   SER SER A . n 
A 1 100 SER 100 91   91   SER SER A . n 
A 1 101 ILE 101 92   92   ILE ILE A . n 
A 1 102 PHE 102 93   93   PHE PHE A . n 
A 1 103 SER 103 94   94   SER SER A . n 
A 1 104 LEU 104 95   95   LEU LEU A . n 
A 1 105 LEU 105 96   96   LEU LEU A . n 
A 1 106 ALA 106 97   97   ALA ALA A . n 
A 1 107 ILE 107 98   98   ILE ILE A . n 
A 1 108 ALA 108 99   99   ALA ALA A . n 
A 1 109 ILE 109 100  100  ILE ILE A . n 
A 1 110 ASP 110 101  101  ASP ASP A . n 
A 1 111 ARG 111 102  102  ARG ARG A . n 
A 1 112 TYR 112 103  103  TYR TYR A . n 
A 1 113 ILE 113 104  104  ILE ILE A . n 
A 1 114 ALA 114 105  105  ALA ALA A . n 
A 1 115 ILE 115 106  106  ILE ILE A . n 
A 1 116 ALA 116 107  107  ALA ALA A . n 
A 1 117 ILE 117 108  108  ILE ILE A . n 
A 1 118 PRO 118 109  109  PRO PRO A . n 
A 1 119 LEU 119 110  110  LEU LEU A . n 
A 1 120 ARG 120 111  111  ARG ARG A . n 
A 1 121 TYR 121 112  112  TYR TYR A . n 
A 1 122 ASN 122 113  113  ASN ASN A . n 
A 1 123 GLY 123 114  114  GLY GLY A . n 
A 1 124 LEU 124 115  115  LEU LEU A . n 
A 1 125 VAL 125 116  116  VAL VAL A . n 
A 1 126 THR 126 117  117  THR THR A . n 
A 1 127 GLY 127 118  118  GLY GLY A . n 
A 1 128 THR 128 119  119  THR THR A . n 
A 1 129 ARG 129 120  120  ARG ARG A . n 
A 1 130 ALA 130 121  121  ALA ALA A . n 
A 1 131 ALA 131 122  122  ALA ALA A . n 
A 1 132 GLY 132 123  123  GLY GLY A . n 
A 1 133 ILE 133 124  124  ILE ILE A . n 
A 1 134 ILE 134 125  125  ILE ILE A . n 
A 1 135 ALA 135 126  126  ALA ALA A . n 
A 1 136 ILE 136 127  127  ILE ILE A . n 
A 1 137 CYS 137 128  128  CYS CYS A . n 
A 1 138 TRP 138 129  129  TRP TRP A . n 
A 1 139 VAL 139 130  130  VAL VAL A . n 
A 1 140 LEU 140 131  131  LEU LEU A . n 
A 1 141 SER 141 132  132  SER SER A . n 
A 1 142 PHE 142 133  133  PHE PHE A . n 
A 1 143 ALA 143 134  134  ALA ALA A . n 
A 1 144 ILE 144 135  135  ILE ILE A . n 
A 1 145 GLY 145 136  136  GLY GLY A . n 
A 1 146 LEU 146 137  137  LEU LEU A . n 
A 1 147 THR 147 138  138  THR THR A . n 
A 1 148 PRO 148 139  139  PRO PRO A . n 
A 1 149 MET 149 140  140  MET MET A . n 
A 1 150 LEU 150 141  141  LEU LEU A . n 
A 1 151 GLY 151 142  142  GLY GLY A . n 
A 1 152 TRP 152 143  143  TRP TRP A . n 
A 1 153 ASN 153 144  144  ASN ASN A . n 
A 1 154 ASN 154 145  145  ASN ASN A . n 
A 1 155 CYS 155 146  146  CYS CYS A . n 
A 1 156 GLY 156 147  147  GLY GLY A . n 
A 1 157 GLN 157 148  148  GLN GLN A . n 
A 1 158 PRO 158 149  149  PRO PRO A . n 
A 1 159 LYS 159 150  150  LYS LYS A . n 
A 1 160 GLU 160 151  151  GLU GLU A . n 
A 1 161 GLY 161 152  152  GLY GLY A . n 
A 1 162 LYS 162 153  153  LYS LYS A . n 
A 1 163 ALA 163 154  154  ALA ALA A . n 
A 1 164 HIS 164 155  155  HIS HIS A . n 
A 1 165 SER 165 156  156  SER SER A . n 
A 1 166 GLN 166 157  157  GLN GLN A . n 
A 1 167 GLY 167 158  158  GLY GLY A . n 
A 1 168 CYS 168 159  159  CYS CYS A . n 
A 1 169 GLY 169 160  160  GLY GLY A . n 
A 1 170 GLU 170 161  161  GLU GLU A . n 
A 1 171 GLY 171 162  162  GLY GLY A . n 
A 1 172 GLN 172 163  163  GLN GLN A . n 
A 1 173 VAL 173 164  164  VAL VAL A . n 
A 1 174 ALA 174 165  165  ALA ALA A . n 
A 1 175 CYS 175 166  166  CYS CYS A . n 
A 1 176 LEU 176 167  167  LEU LEU A . n 
A 1 177 PHE 177 168  168  PHE PHE A . n 
A 1 178 GLU 178 169  169  GLU GLU A . n 
A 1 179 ASP 179 170  170  ASP ASP A . n 
A 1 180 VAL 180 171  171  VAL VAL A . n 
A 1 181 VAL 181 172  172  VAL VAL A . n 
A 1 182 PRO 182 173  173  PRO PRO A . n 
A 1 183 MET 183 174  174  MET MET A . n 
A 1 184 ASN 184 175  175  ASN ASN A . n 
A 1 185 TYR 185 176  176  TYR TYR A . n 
A 1 186 MET 186 177  177  MET MET A . n 
A 1 187 VAL 187 178  178  VAL VAL A . n 
A 1 188 TYR 188 179  179  TYR TYR A . n 
A 1 189 PHE 189 180  180  PHE PHE A . n 
A 1 190 ASN 190 181  181  ASN ASN A . n 
A 1 191 PHE 191 182  182  PHE PHE A . n 
A 1 192 PHE 192 183  183  PHE PHE A . n 
A 1 193 ALA 193 184  184  ALA ALA A . n 
A 1 194 CYS 194 185  185  CYS CYS A . n 
A 1 195 VAL 195 186  186  VAL VAL A . n 
A 1 196 LEU 196 187  187  LEU LEU A . n 
A 1 197 VAL 197 188  188  VAL VAL A . n 
A 1 198 PRO 198 189  189  PRO PRO A . n 
A 1 199 LEU 199 190  190  LEU LEU A . n 
A 1 200 LEU 200 191  191  LEU LEU A . n 
A 1 201 LEU 201 192  192  LEU LEU A . n 
A 1 202 MET 202 193  193  MET MET A . n 
A 1 203 LEU 203 194  194  LEU LEU A . n 
A 1 204 GLY 204 195  195  GLY GLY A . n 
A 1 205 VAL 205 196  196  VAL VAL A . n 
A 1 206 TYR 206 197  197  TYR TYR A . n 
A 1 207 LEU 207 198  198  LEU LEU A . n 
A 1 208 ARG 208 199  199  ARG ARG A . n 
A 1 209 ILE 209 200  200  ILE ILE A . n 
A 1 210 PHE 210 201  201  PHE PHE A . n 
A 1 211 ALA 211 202  202  ALA ALA A . n 
A 1 212 ALA 212 203  203  ALA ALA A . n 
A 1 213 ALA 213 204  204  ALA ALA A . n 
A 1 214 ARG 214 205  205  ARG ARG A . n 
A 1 215 ARG 215 206  206  ARG ARG A . n 
A 1 216 GLN 216 207  207  GLN GLN A . n 
A 1 217 LEU 217 208  208  LEU LEU A . n 
A 1 218 ALA 218 1001 1001 ALA ALA A . n 
A 1 219 ASP 219 1002 1002 ASP ASP A . n 
A 1 220 LEU 220 1003 1003 LEU LEU A . n 
A 1 221 GLU 221 1004 1004 GLU GLU A . n 
A 1 222 ASP 222 1005 1005 ASP ASP A . n 
A 1 223 ASN 223 1006 1006 ASN ASN A . n 
A 1 224 TRP 224 1007 1007 TRP TRP A . n 
A 1 225 GLU 225 1008 1008 GLU GLU A . n 
A 1 226 THR 226 1009 1009 THR THR A . n 
A 1 227 LEU 227 1010 1010 LEU LEU A . n 
A 1 228 ASN 228 1011 1011 ASN ASN A . n 
A 1 229 ASP 229 1012 1012 ASP ASP A . n 
A 1 230 ASN 230 1013 1013 ASN ASN A . n 
A 1 231 LEU 231 1014 1014 LEU LEU A . n 
A 1 232 LYS 232 1015 1015 LYS LYS A . n 
A 1 233 VAL 233 1016 1016 VAL VAL A . n 
A 1 234 ILE 234 1017 1017 ILE ILE A . n 
A 1 235 GLU 235 1018 1018 GLU GLU A . n 
A 1 236 LYS 236 1019 1019 LYS LYS A . n 
A 1 237 ALA 237 1020 1020 ALA ALA A . n 
A 1 238 ASP 238 1021 1021 ASP ASP A . n 
A 1 239 ASN 239 1022 1022 ASN ASN A . n 
A 1 240 ALA 240 1023 1023 ALA ALA A . n 
A 1 241 ALA 241 1024 1024 ALA ALA A . n 
A 1 242 GLN 242 1025 1025 GLN GLN A . n 
A 1 243 VAL 243 1026 1026 VAL VAL A . n 
A 1 244 LYS 244 1027 1027 LYS LYS A . n 
A 1 245 ASP 245 1028 1028 ASP ASP A . n 
A 1 246 ALA 246 1029 1029 ALA ALA A . n 
A 1 247 LEU 247 1030 1030 LEU LEU A . n 
A 1 248 THR 248 1031 1031 THR THR A . n 
A 1 249 LYS 249 1032 1032 LYS LYS A . n 
A 1 250 MET 250 1033 1033 MET MET A . n 
A 1 251 ARG 251 1034 1034 ARG ARG A . n 
A 1 252 ALA 252 1035 1035 ALA ALA A . n 
A 1 253 ALA 253 1036 1036 ALA ALA A . n 
A 1 254 ALA 254 1037 1037 ALA ALA A . n 
A 1 255 LEU 255 1038 1038 LEU LEU A . n 
A 1 256 ASP 256 1039 1039 ASP ASP A . n 
A 1 257 ALA 257 1040 1040 ALA ALA A . n 
A 1 258 GLN 258 1041 1041 GLN GLN A . n 
A 1 259 LYS 259 1042 1042 LYS LYS A . n 
A 1 260 ALA 260 1043 1043 ALA ALA A . n 
A 1 261 THR 261 1044 ?    ?   ?   A . n 
A 1 262 PRO 262 1045 ?    ?   ?   A . n 
A 1 263 PRO 263 1046 ?    ?   ?   A . n 
A 1 264 LYS 264 1047 ?    ?   ?   A . n 
A 1 265 LEU 265 1048 ?    ?   ?   A . n 
A 1 266 GLU 266 1049 ?    ?   ?   A . n 
A 1 267 ASP 267 1050 ?    ?   ?   A . n 
A 1 268 LYS 268 1051 ?    ?   ?   A . n 
A 1 269 SER 269 1052 ?    ?   ?   A . n 
A 1 270 PRO 270 1053 ?    ?   ?   A . n 
A 1 271 ASP 271 1054 ?    ?   ?   A . n 
A 1 272 SER 272 1055 ?    ?   ?   A . n 
A 1 273 PRO 273 1056 ?    ?   ?   A . n 
A 1 274 GLU 274 1057 ?    ?   ?   A . n 
A 1 275 MET 275 1058 ?    ?   ?   A . n 
A 1 276 LYS 276 1059 ?    ?   ?   A . n 
A 1 277 ASP 277 1060 ?    ?   ?   A . n 
A 1 278 PHE 278 1061 ?    ?   ?   A . n 
A 1 279 ARG 279 1062 ?    ?   ?   A . n 
A 1 280 HIS 280 1063 1063 HIS HIS A . n 
A 1 281 GLY 281 1064 1064 GLY GLY A . n 
A 1 282 PHE 282 1065 1065 PHE PHE A . n 
A 1 283 ASP 283 1066 1066 ASP ASP A . n 
A 1 284 ILE 284 1067 1067 ILE ILE A . n 
A 1 285 LEU 285 1068 1068 LEU LEU A . n 
A 1 286 VAL 286 1069 1069 VAL VAL A . n 
A 1 287 GLY 287 1070 1070 GLY GLY A . n 
A 1 288 GLN 288 1071 1071 GLN GLN A . n 
A 1 289 ILE 289 1072 1072 ILE ILE A . n 
A 1 290 ASP 290 1073 1073 ASP ASP A . n 
A 1 291 ASP 291 1074 1074 ASP ASP A . n 
A 1 292 ALA 292 1075 1075 ALA ALA A . n 
A 1 293 LEU 293 1076 1076 LEU LEU A . n 
A 1 294 LYS 294 1077 1077 LYS LYS A . n 
A 1 295 LEU 295 1078 1078 LEU LEU A . n 
A 1 296 ALA 296 1079 1079 ALA ALA A . n 
A 1 297 ASN 297 1080 1080 ASN ASN A . n 
A 1 298 GLU 298 1081 1081 GLU GLU A . n 
A 1 299 GLY 299 1082 1082 GLY GLY A . n 
A 1 300 LYS 300 1083 1083 LYS LYS A . n 
A 1 301 VAL 301 1084 1084 VAL VAL A . n 
A 1 302 LYS 302 1085 1085 LYS LYS A . n 
A 1 303 GLU 303 1086 1086 GLU GLU A . n 
A 1 304 ALA 304 1087 1087 ALA ALA A . n 
A 1 305 GLN 305 1088 1088 GLN GLN A . n 
A 1 306 ALA 306 1089 1089 ALA ALA A . n 
A 1 307 ALA 307 1090 1090 ALA ALA A . n 
A 1 308 ALA 308 1091 1091 ALA ALA A . n 
A 1 309 GLU 309 1092 1092 GLU GLU A . n 
A 1 310 GLN 310 1093 1093 GLN GLN A . n 
A 1 311 LEU 311 1094 1094 LEU LEU A . n 
A 1 312 LYS 312 1095 1095 LYS LYS A . n 
A 1 313 THR 313 1096 1096 THR THR A . n 
A 1 314 THR 314 1097 1097 THR THR A . n 
A 1 315 ARG 315 1098 1098 ARG ARG A . n 
A 1 316 ASN 316 1099 1099 ASN ASN A . n 
A 1 317 ALA 317 1100 1100 ALA ALA A . n 
A 1 318 TYR 318 1101 1101 TYR TYR A . n 
A 1 319 ILE 319 1102 1102 ILE ILE A . n 
A 1 320 GLN 320 1103 1103 GLN GLN A . n 
A 1 321 LYS 321 1104 1104 LYS LYS A . n 
A 1 322 TYR 322 1105 1105 TYR TYR A . n 
A 1 323 LEU 323 1106 1106 LEU LEU A . n 
A 1 324 GLU 324 219  219  GLU GLU A . n 
A 1 325 ARG 325 220  220  ARG ARG A . n 
A 1 326 ALA 326 221  221  ALA ALA A . n 
A 1 327 ARG 327 222  222  ARG ARG A . n 
A 1 328 SER 328 223  223  SER SER A . n 
A 1 329 THR 329 224  224  THR THR A . n 
A 1 330 LEU 330 225  225  LEU LEU A . n 
A 1 331 GLN 331 226  226  GLN GLN A . n 
A 1 332 LYS 332 227  227  LYS LYS A . n 
A 1 333 GLU 333 228  228  GLU GLU A . n 
A 1 334 VAL 334 229  229  VAL VAL A . n 
A 1 335 HIS 335 230  230  HIS HIS A . n 
A 1 336 ALA 336 231  231  ALA ALA A . n 
A 1 337 ALA 337 232  232  ALA ALA A . n 
A 1 338 LYS 338 233  233  LYS LYS A . n 
A 1 339 SER 339 234  234  SER SER A . n 
A 1 340 ALA 340 235  235  ALA ALA A . n 
A 1 341 ALA 341 236  236  ALA ALA A . n 
A 1 342 ILE 342 237  237  ILE ILE A . n 
A 1 343 ILE 343 238  238  ILE ILE A . n 
A 1 344 ALA 344 239  239  ALA ALA A . n 
A 1 345 GLY 345 240  240  GLY GLY A . n 
A 1 346 LEU 346 241  241  LEU LEU A . n 
A 1 347 PHE 347 242  242  PHE PHE A . n 
A 1 348 ALA 348 243  243  ALA ALA A . n 
A 1 349 LEU 349 244  244  LEU LEU A . n 
A 1 350 CYS 350 245  245  CYS CYS A . n 
A 1 351 TRP 351 246  246  TRP TRP A . n 
A 1 352 LEU 352 247  247  LEU LEU A . n 
A 1 353 PRO 353 248  248  PRO PRO A . n 
A 1 354 LEU 354 249  249  LEU LEU A . n 
A 1 355 HIS 355 250  250  HIS HIS A . n 
A 1 356 ILE 356 251  251  ILE ILE A . n 
A 1 357 ILE 357 252  252  ILE ILE A . n 
A 1 358 ASN 358 253  253  ASN ASN A . n 
A 1 359 CYS 359 254  254  CYS CYS A . n 
A 1 360 PHE 360 255  255  PHE PHE A . n 
A 1 361 THR 361 256  256  THR THR A . n 
A 1 362 PHE 362 257  257  PHE PHE A . n 
A 1 363 PHE 363 258  258  PHE PHE A . n 
A 1 364 CYS 364 259  259  CYS CYS A . n 
A 1 365 PRO 365 260  260  PRO PRO A . n 
A 1 366 ASP 366 261  261  ASP ASP A . n 
A 1 367 CYS 367 262  262  CYS CYS A . n 
A 1 368 SER 368 263  263  SER SER A . n 
A 1 369 HIS 369 264  264  HIS HIS A . n 
A 1 370 ALA 370 265  265  ALA ALA A . n 
A 1 371 PRO 371 266  266  PRO PRO A . n 
A 1 372 LEU 372 267  267  LEU LEU A . n 
A 1 373 TRP 373 268  268  TRP TRP A . n 
A 1 374 LEU 374 269  269  LEU LEU A . n 
A 1 375 MET 375 270  270  MET MET A . n 
A 1 376 TYR 376 271  271  TYR TYR A . n 
A 1 377 LEU 377 272  272  LEU LEU A . n 
A 1 378 ALA 378 273  273  ALA ALA A . n 
A 1 379 ILE 379 274  274  ILE ILE A . n 
A 1 380 VAL 380 275  275  VAL VAL A . n 
A 1 381 LEU 381 276  276  LEU LEU A . n 
A 1 382 ALA 382 277  277  ALA ALA A . n 
A 1 383 HIS 383 278  278  HIS HIS A . n 
A 1 384 THR 384 279  279  THR THR A . n 
A 1 385 ASN 385 280  280  ASN ASN A . n 
A 1 386 SER 386 281  281  SER SER A . n 
A 1 387 VAL 387 282  282  VAL VAL A . n 
A 1 388 VAL 388 283  283  VAL VAL A . n 
A 1 389 ASN 389 284  284  ASN ASN A . n 
A 1 390 PRO 390 285  285  PRO PRO A . n 
A 1 391 PHE 391 286  286  PHE PHE A . n 
A 1 392 ILE 392 287  287  ILE ILE A . n 
A 1 393 TYR 393 288  288  TYR TYR A . n 
A 1 394 ALA 394 289  289  ALA ALA A . n 
A 1 395 TYR 395 290  290  TYR TYR A . n 
A 1 396 ARG 396 291  291  ARG ARG A . n 
A 1 397 ILE 397 292  292  ILE ILE A . n 
A 1 398 ARG 398 293  293  ARG ARG A . n 
A 1 399 GLU 399 294  294  GLU GLU A . n 
A 1 400 PHE 400 295  295  PHE PHE A . n 
A 1 401 ARG 401 296  296  ARG ARG A . n 
A 1 402 GLN 402 297  297  GLN GLN A . n 
A 1 403 THR 403 298  298  THR THR A . n 
A 1 404 PHE 404 299  299  PHE PHE A . n 
A 1 405 ARG 405 300  300  ARG ARG A . n 
A 1 406 LYS 406 301  301  LYS LYS A . n 
A 1 407 ILE 407 302  302  ILE ILE A . n 
A 1 408 ILE 408 303  303  ILE ILE A . n 
A 1 409 ARG 409 304  304  ARG ARG A . n 
A 1 410 SER 410 305  305  SER SER A . n 
A 1 411 HIS 411 306  ?    ?   ?   A . n 
A 1 412 VAL 412 307  ?    ?   ?   A . n 
A 1 413 LEU 413 308  ?    ?   ?   A . n 
A 1 414 ARG 414 309  ?    ?   ?   A . n 
A 1 415 GLN 415 310  ?    ?   ?   A . n 
A 1 416 GLN 416 311  ?    ?   ?   A . n 
A 1 417 GLU 417 312  ?    ?   ?   A . n 
A 1 418 PRO 418 313  ?    ?   ?   A . n 
A 1 419 PHE 419 314  ?    ?   ?   A . n 
A 1 420 LYS 420 315  ?    ?   ?   A . n 
A 1 421 ALA 421 316  ?    ?   ?   A . n 
A 1 422 ALA 422 317  ?    ?   ?   A . n 
A 1 423 ALA 423 318  ?    ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        JQ9 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   JQ9 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 NA  1  1201 1201 NA  NA  A . 
C 3 CLR 1  1202 1202 CLR CLR A . 
D 3 CLR 1  1203 1203 CLR CLR A . 
E 3 CLR 1  1204 1204 CLR CLR A . 
F 4 OLA 1  1205 1205 OLA OLA A . 
G 4 OLA 1  1206 1206 OLA OLA A . 
H 4 OLA 1  1207 1207 OLA OLA A . 
I 4 OLA 1  1208 1208 OLA OLA A . 
J 4 OLA 1  1209 1210 OLA OLA A . 
K 4 OLA 1  1210 1211 OLA OLA A . 
L 4 OLA 1  1211 1212 OLA OLA A . 
M 4 OLA 1  1212 1213 OLA OLA A . 
N 4 OLA 1  1213 1214 OLA OLA A . 
O 4 OLA 1  1214 1215 OLA OLA A . 
P 4 OLA 1  1215 1218 OLA OLA A . 
Q 5 OLB 1  1216 1220 OLB OLB A . 
R 5 OLB 1  1217 1221 OLB OLB A . 
S 6 OLC 1  1218 1222 OLC OLC A . 
T 6 OLC 1  1219 1223 OLC OLC A . 
U 7 JQ9 1  1220 1224 JQ9 JQ9 A . 
V 8 HOH 1  1301 162  HOH HOH A . 
V 8 HOH 2  1302 1    HOH HOH A . 
V 8 HOH 3  1303 168  HOH HOH A . 
V 8 HOH 4  1304 163  HOH HOH A . 
V 8 HOH 5  1305 164  HOH HOH A . 
V 8 HOH 6  1306 43   HOH HOH A . 
V 8 HOH 7  1307 160  HOH HOH A . 
V 8 HOH 8  1308 23   HOH HOH A . 
V 8 HOH 9  1309 37   HOH HOH A . 
V 8 HOH 10 1310 49   HOH HOH A . 
V 8 HOH 11 1311 32   HOH HOH A . 
V 8 HOH 12 1312 166  HOH HOH A . 
V 8 HOH 13 1313 40   HOH HOH A . 
V 8 HOH 14 1314 7    HOH HOH A . 
V 8 HOH 15 1315 156  HOH HOH A . 
V 8 HOH 16 1316 36   HOH HOH A . 
V 8 HOH 17 1317 26   HOH HOH A . 
V 8 HOH 18 1318 3    HOH HOH A . 
V 8 HOH 19 1319 10   HOH HOH A . 
V 8 HOH 20 1320 46   HOH HOH A . 
V 8 HOH 21 1321 150  HOH HOH A . 
V 8 HOH 22 1322 11   HOH HOH A . 
V 8 HOH 23 1323 161  HOH HOH A . 
V 8 HOH 24 1324 15   HOH HOH A . 
V 8 HOH 25 1325 159  HOH HOH A . 
V 8 HOH 26 1326 109  HOH HOH A . 
V 8 HOH 27 1327 4    HOH HOH A . 
V 8 HOH 28 1328 2    HOH HOH A . 
V 8 HOH 29 1329 154  HOH HOH A . 
V 8 HOH 30 1330 48   HOH HOH A . 
V 8 HOH 31 1331 169  HOH HOH A . 
V 8 HOH 32 1332 155  HOH HOH A . 
V 8 HOH 33 1333 157  HOH HOH A . 
V 8 HOH 34 1334 165  HOH HOH A . 
V 8 HOH 35 1335 47   HOH HOH A . 
V 8 HOH 36 1336 158  HOH HOH A . 
V 8 HOH 37 1337 167  HOH HOH A . 
V 8 HOH 38 1338 89   HOH HOH A . 
V 8 HOH 39 1339 62   HOH HOH A . 
V 8 HOH 40 1340 152  HOH HOH A . 
V 8 HOH 41 1341 153  HOH HOH A . 
V 8 HOH 42 1342 151  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LEU 110  ? CG  ? A LEU 119 CG  
2   1 Y 1 A LEU 110  ? CD1 ? A LEU 119 CD1 
3   1 Y 1 A LEU 110  ? CD2 ? A LEU 119 CD2 
4   1 Y 1 A ARG 111  ? CG  ? A ARG 120 CG  
5   1 Y 1 A ARG 111  ? CD  ? A ARG 120 CD  
6   1 Y 1 A ARG 111  ? NE  ? A ARG 120 NE  
7   1 Y 1 A ARG 111  ? CZ  ? A ARG 120 CZ  
8   1 Y 1 A ARG 111  ? NH1 ? A ARG 120 NH1 
9   1 Y 1 A ARG 111  ? NH2 ? A ARG 120 NH2 
10  1 Y 1 A ASN 113  ? CG  ? A ASN 122 CG  
11  1 Y 1 A ASN 113  ? OD1 ? A ASN 122 OD1 
12  1 Y 1 A ASN 113  ? ND2 ? A ASN 122 ND2 
13  1 Y 1 A GLN 148  ? CG  ? A GLN 157 CG  
14  1 Y 1 A GLN 148  ? CD  ? A GLN 157 CD  
15  1 Y 1 A GLN 148  ? OE1 ? A GLN 157 OE1 
16  1 Y 1 A GLN 148  ? NE2 ? A GLN 157 NE2 
17  1 Y 1 A GLU 151  ? CG  ? A GLU 160 CG  
18  1 Y 1 A GLU 151  ? CD  ? A GLU 160 CD  
19  1 Y 1 A GLU 151  ? OE1 ? A GLU 160 OE1 
20  1 Y 1 A GLU 151  ? OE2 ? A GLU 160 OE2 
21  1 Y 1 A GLU 161  ? CG  ? A GLU 170 CG  
22  1 Y 1 A GLU 161  ? CD  ? A GLU 170 CD  
23  1 Y 1 A GLU 161  ? OE1 ? A GLU 170 OE1 
24  1 Y 1 A GLU 161  ? OE2 ? A GLU 170 OE2 
25  1 Y 1 A ARG 205  ? CG  ? A ARG 214 CG  
26  1 Y 1 A ARG 205  ? CD  ? A ARG 214 CD  
27  1 Y 1 A ARG 205  ? NE  ? A ARG 214 NE  
28  1 Y 1 A ARG 205  ? CZ  ? A ARG 214 CZ  
29  1 Y 1 A ARG 205  ? NH1 ? A ARG 214 NH1 
30  1 Y 1 A ARG 205  ? NH2 ? A ARG 214 NH2 
31  1 Y 1 A ARG 206  ? CG  ? A ARG 215 CG  
32  1 Y 1 A ARG 206  ? CD  ? A ARG 215 CD  
33  1 Y 1 A ARG 206  ? NE  ? A ARG 215 NE  
34  1 Y 1 A ARG 206  ? CZ  ? A ARG 215 CZ  
35  1 Y 1 A ARG 206  ? NH1 ? A ARG 215 NH1 
36  1 Y 1 A ARG 206  ? NH2 ? A ARG 215 NH2 
37  1 Y 1 A GLU 1008 ? CG  ? A GLU 225 CG  
38  1 Y 1 A GLU 1008 ? CD  ? A GLU 225 CD  
39  1 Y 1 A GLU 1008 ? OE1 ? A GLU 225 OE1 
40  1 Y 1 A GLU 1008 ? OE2 ? A GLU 225 OE2 
41  1 Y 1 A LYS 1015 ? CG  ? A LYS 232 CG  
42  1 Y 1 A LYS 1015 ? CD  ? A LYS 232 CD  
43  1 Y 1 A LYS 1015 ? CE  ? A LYS 232 CE  
44  1 Y 1 A LYS 1015 ? NZ  ? A LYS 232 NZ  
45  1 Y 1 A ILE 1017 ? CG1 ? A ILE 234 CG1 
46  1 Y 1 A ILE 1017 ? CG2 ? A ILE 234 CG2 
47  1 Y 1 A ILE 1017 ? CD1 ? A ILE 234 CD1 
48  1 Y 1 A LYS 1019 ? CG  ? A LYS 236 CG  
49  1 Y 1 A LYS 1019 ? CD  ? A LYS 236 CD  
50  1 Y 1 A LYS 1019 ? CE  ? A LYS 236 CE  
51  1 Y 1 A LYS 1019 ? NZ  ? A LYS 236 NZ  
52  1 Y 1 A LYS 1027 ? CG  ? A LYS 244 CG  
53  1 Y 1 A LYS 1027 ? CD  ? A LYS 244 CD  
54  1 Y 1 A LYS 1027 ? CE  ? A LYS 244 CE  
55  1 Y 1 A LYS 1027 ? NZ  ? A LYS 244 NZ  
56  1 Y 1 A LYS 1032 ? CG  ? A LYS 249 CG  
57  1 Y 1 A LYS 1032 ? CD  ? A LYS 249 CD  
58  1 Y 1 A LYS 1032 ? CE  ? A LYS 249 CE  
59  1 Y 1 A LYS 1032 ? NZ  ? A LYS 249 NZ  
60  1 Y 1 A GLN 1041 ? CG  ? A GLN 258 CG  
61  1 Y 1 A GLN 1041 ? CD  ? A GLN 258 CD  
62  1 Y 1 A GLN 1041 ? OE1 ? A GLN 258 OE1 
63  1 Y 1 A GLN 1041 ? NE2 ? A GLN 258 NE2 
64  1 Y 1 A LYS 1042 ? CG  ? A LYS 259 CG  
65  1 Y 1 A LYS 1042 ? CD  ? A LYS 259 CD  
66  1 Y 1 A LYS 1042 ? CE  ? A LYS 259 CE  
67  1 Y 1 A LYS 1042 ? NZ  ? A LYS 259 NZ  
68  1 Y 1 A HIS 1063 ? CG  ? A HIS 280 CG  
69  1 Y 1 A HIS 1063 ? ND1 ? A HIS 280 ND1 
70  1 Y 1 A HIS 1063 ? CD2 ? A HIS 280 CD2 
71  1 Y 1 A HIS 1063 ? CE1 ? A HIS 280 CE1 
72  1 Y 1 A HIS 1063 ? NE2 ? A HIS 280 NE2 
73  1 Y 1 A LYS 1077 ? CG  ? A LYS 294 CG  
74  1 Y 1 A LYS 1077 ? CD  ? A LYS 294 CD  
75  1 Y 1 A LYS 1077 ? CE  ? A LYS 294 CE  
76  1 Y 1 A LYS 1077 ? NZ  ? A LYS 294 NZ  
77  1 Y 1 A ASN 1080 ? CG  ? A ASN 297 CG  
78  1 Y 1 A ASN 1080 ? OD1 ? A ASN 297 OD1 
79  1 Y 1 A ASN 1080 ? ND2 ? A ASN 297 ND2 
80  1 Y 1 A LYS 1083 ? CG  ? A LYS 300 CG  
81  1 Y 1 A LYS 1083 ? CD  ? A LYS 300 CD  
82  1 Y 1 A LYS 1083 ? CE  ? A LYS 300 CE  
83  1 Y 1 A LYS 1083 ? NZ  ? A LYS 300 NZ  
84  1 Y 1 A GLU 1086 ? CG  ? A GLU 303 CG  
85  1 Y 1 A GLU 1086 ? CD  ? A GLU 303 CD  
86  1 Y 1 A GLU 1086 ? OE1 ? A GLU 303 OE1 
87  1 Y 1 A GLU 1086 ? OE2 ? A GLU 303 OE2 
88  1 Y 1 A LYS 1095 ? CG  ? A LYS 312 CG  
89  1 Y 1 A LYS 1095 ? CD  ? A LYS 312 CD  
90  1 Y 1 A LYS 1095 ? CE  ? A LYS 312 CE  
91  1 Y 1 A LYS 1095 ? NZ  ? A LYS 312 NZ  
92  1 Y 1 A TYR 1101 ? CG  ? A TYR 318 CG  
93  1 Y 1 A TYR 1101 ? CD1 ? A TYR 318 CD1 
94  1 Y 1 A TYR 1101 ? CD2 ? A TYR 318 CD2 
95  1 Y 1 A TYR 1101 ? CE1 ? A TYR 318 CE1 
96  1 Y 1 A TYR 1101 ? CE2 ? A TYR 318 CE2 
97  1 Y 1 A TYR 1101 ? CZ  ? A TYR 318 CZ  
98  1 Y 1 A TYR 1101 ? OH  ? A TYR 318 OH  
99  1 Y 1 A GLN 1103 ? CG  ? A GLN 320 CG  
100 1 Y 1 A GLN 1103 ? CD  ? A GLN 320 CD  
101 1 Y 1 A GLN 1103 ? OE1 ? A GLN 320 OE1 
102 1 Y 1 A GLN 1103 ? NE2 ? A GLN 320 NE2 
103 1 Y 1 A LYS 1104 ? CG  ? A LYS 321 CG  
104 1 Y 1 A LYS 1104 ? CD  ? A LYS 321 CD  
105 1 Y 1 A LYS 1104 ? CE  ? A LYS 321 CE  
106 1 Y 1 A LYS 1104 ? NZ  ? A LYS 321 NZ  
107 1 Y 1 A ARG 220  ? CG  ? A ARG 325 CG  
108 1 Y 1 A ARG 220  ? CD  ? A ARG 325 CD  
109 1 Y 1 A ARG 220  ? NE  ? A ARG 325 NE  
110 1 Y 1 A ARG 220  ? CZ  ? A ARG 325 CZ  
111 1 Y 1 A ARG 220  ? NH1 ? A ARG 325 NH1 
112 1 Y 1 A ARG 220  ? NH2 ? A ARG 325 NH2 
113 1 Y 1 A ARG 222  ? CG  ? A ARG 327 CG  
114 1 Y 1 A ARG 222  ? CD  ? A ARG 327 CD  
115 1 Y 1 A ARG 222  ? NE  ? A ARG 327 NE  
116 1 Y 1 A ARG 222  ? CZ  ? A ARG 327 CZ  
117 1 Y 1 A ARG 222  ? NH1 ? A ARG 327 NH1 
118 1 Y 1 A ARG 222  ? NH2 ? A ARG 327 NH2 
119 1 Y 1 A GLN 226  ? CG  ? A GLN 331 CG  
120 1 Y 1 A GLN 226  ? CD  ? A GLN 331 CD  
121 1 Y 1 A GLN 226  ? OE1 ? A GLN 331 OE1 
122 1 Y 1 A GLN 226  ? NE2 ? A GLN 331 NE2 
123 1 Y 1 A GLU 228  ? CG  ? A GLU 333 CG  
124 1 Y 1 A GLU 228  ? CD  ? A GLU 333 CD  
125 1 Y 1 A GLU 228  ? OE1 ? A GLU 333 OE1 
126 1 Y 1 A GLU 228  ? OE2 ? A GLU 333 OE2 
127 1 Y 1 A LYS 233  ? CG  ? A LYS 338 CG  
128 1 Y 1 A LYS 233  ? CD  ? A LYS 338 CD  
129 1 Y 1 A LYS 233  ? CE  ? A LYS 338 CE  
130 1 Y 1 A LYS 233  ? NZ  ? A LYS 338 NZ  
131 1 Y 1 A ARG 293  ? CG  ? A ARG 398 CG  
132 1 Y 1 A ARG 293  ? CD  ? A ARG 398 CD  
133 1 Y 1 A ARG 293  ? NE  ? A ARG 398 NE  
134 1 Y 1 A ARG 293  ? CZ  ? A ARG 398 CZ  
135 1 Y 1 A ARG 293  ? NH1 ? A ARG 398 NH1 
136 1 Y 1 A ARG 293  ? NH2 ? A ARG 398 NH2 
137 1 Y 1 A LYS 301  ? CG  ? A LYS 406 CG  
138 1 Y 1 A LYS 301  ? CD  ? A LYS 406 CD  
139 1 Y 1 A LYS 301  ? CE  ? A LYS 406 CE  
140 1 Y 1 A LYS 301  ? NZ  ? A LYS 406 NZ  
141 1 Y 1 A ARG 304  ? CG  ? A ARG 409 CG  
142 1 Y 1 A ARG 304  ? CD  ? A ARG 409 CD  
143 1 Y 1 A ARG 304  ? NE  ? A ARG 409 NE  
144 1 Y 1 A ARG 304  ? CZ  ? A ARG 409 CZ  
145 1 Y 1 A ARG 304  ? NH1 ? A ARG 409 NH1 
146 1 Y 1 A ARG 304  ? NH2 ? A ARG 409 NH2 
147 1 N 1 A OLA 1206 ? C14 ? G OLA 1   C14 
148 1 N 1 A OLA 1206 ? C15 ? G OLA 1   C15 
149 1 N 1 A OLA 1206 ? C16 ? G OLA 1   C16 
150 1 N 1 A OLA 1206 ? C17 ? G OLA 1   C17 
151 1 N 1 A OLA 1206 ? C18 ? G OLA 1   C18 
152 1 N 1 A OLA 1207 ? C8  ? H OLA 1   C8  
153 1 N 1 A OLA 1207 ? C9  ? H OLA 1   C9  
154 1 N 1 A OLA 1207 ? C10 ? H OLA 1   C10 
155 1 N 1 A OLA 1207 ? C11 ? H OLA 1   C11 
156 1 N 1 A OLA 1207 ? C12 ? H OLA 1   C12 
157 1 N 1 A OLA 1207 ? C13 ? H OLA 1   C13 
158 1 N 1 A OLA 1207 ? C14 ? H OLA 1   C14 
159 1 N 1 A OLA 1207 ? C15 ? H OLA 1   C15 
160 1 N 1 A OLA 1207 ? C16 ? H OLA 1   C16 
161 1 N 1 A OLA 1207 ? C17 ? H OLA 1   C17 
162 1 N 1 A OLA 1207 ? C18 ? H OLA 1   C18 
163 1 N 1 A OLA 1208 ? C17 ? I OLA 1   C17 
164 1 N 1 A OLA 1208 ? C18 ? I OLA 1   C18 
165 1 N 1 A OLA 1209 ? C11 ? J OLA 1   C11 
166 1 N 1 A OLA 1209 ? C12 ? J OLA 1   C12 
167 1 N 1 A OLA 1209 ? C13 ? J OLA 1   C13 
168 1 N 1 A OLA 1209 ? C14 ? J OLA 1   C14 
169 1 N 1 A OLA 1209 ? C15 ? J OLA 1   C15 
170 1 N 1 A OLA 1209 ? C16 ? J OLA 1   C16 
171 1 N 1 A OLA 1209 ? C17 ? J OLA 1   C17 
172 1 N 1 A OLA 1209 ? C18 ? J OLA 1   C18 
173 1 N 1 A OLA 1210 ? O1  ? K OLA 1   O1  
174 1 N 1 A OLA 1210 ? O2  ? K OLA 1   O2  
175 1 N 1 A OLA 1210 ? C8  ? K OLA 1   C8  
176 1 N 1 A OLA 1210 ? C9  ? K OLA 1   C9  
177 1 N 1 A OLA 1210 ? C10 ? K OLA 1   C10 
178 1 N 1 A OLA 1210 ? C11 ? K OLA 1   C11 
179 1 N 1 A OLA 1210 ? C12 ? K OLA 1   C12 
180 1 N 1 A OLA 1210 ? C13 ? K OLA 1   C13 
181 1 N 1 A OLA 1210 ? C14 ? K OLA 1   C14 
182 1 N 1 A OLA 1210 ? C15 ? K OLA 1   C15 
183 1 N 1 A OLA 1210 ? C16 ? K OLA 1   C16 
184 1 N 1 A OLA 1210 ? C17 ? K OLA 1   C17 
185 1 N 1 A OLA 1210 ? C18 ? K OLA 1   C18 
186 1 N 1 A OLA 1211 ? C18 ? L OLA 1   C18 
187 1 N 1 A OLA 1212 ? C1  ? M OLA 1   C1  
188 1 N 1 A OLA 1212 ? O1  ? M OLA 1   O1  
189 1 N 1 A OLA 1212 ? O2  ? M OLA 1   O2  
190 1 N 1 A OLA 1212 ? C2  ? M OLA 1   C2  
191 1 N 1 A OLA 1212 ? C3  ? M OLA 1   C3  
192 1 N 1 A OLA 1212 ? C4  ? M OLA 1   C4  
193 1 N 1 A OLA 1212 ? C5  ? M OLA 1   C5  
194 1 N 1 A OLA 1212 ? C6  ? M OLA 1   C6  
195 1 N 1 A OLA 1212 ? C7  ? M OLA 1   C7  
196 1 N 1 A OLA 1212 ? C8  ? M OLA 1   C8  
197 1 N 1 A OLA 1213 ? C1  ? N OLA 1   C1  
198 1 N 1 A OLA 1213 ? O1  ? N OLA 1   O1  
199 1 N 1 A OLA 1213 ? O2  ? N OLA 1   O2  
200 1 N 1 A OLA 1213 ? C2  ? N OLA 1   C2  
201 1 N 1 A OLA 1213 ? C10 ? N OLA 1   C10 
202 1 N 1 A OLA 1213 ? C11 ? N OLA 1   C11 
203 1 N 1 A OLA 1213 ? C12 ? N OLA 1   C12 
204 1 N 1 A OLA 1213 ? C13 ? N OLA 1   C13 
205 1 N 1 A OLA 1213 ? C14 ? N OLA 1   C14 
206 1 N 1 A OLA 1213 ? C15 ? N OLA 1   C15 
207 1 N 1 A OLA 1213 ? C16 ? N OLA 1   C16 
208 1 N 1 A OLA 1213 ? C17 ? N OLA 1   C17 
209 1 N 1 A OLA 1213 ? C18 ? N OLA 1   C18 
210 1 N 1 A OLA 1214 ? C16 ? O OLA 1   C16 
211 1 N 1 A OLA 1214 ? C17 ? O OLA 1   C17 
212 1 N 1 A OLA 1214 ? C18 ? O OLA 1   C18 
213 1 N 1 A OLA 1215 ? C16 ? P OLA 1   C16 
214 1 N 1 A OLA 1215 ? C17 ? P OLA 1   C17 
215 1 N 1 A OLA 1215 ? C18 ? P OLA 1   C18 
216 1 N 1 A OLB 1216 ? C13 ? Q OLB 1   C13 
217 1 N 1 A OLB 1216 ? C14 ? Q OLB 1   C14 
218 1 N 1 A OLB 1216 ? C15 ? Q OLB 1   C15 
219 1 N 1 A OLB 1216 ? C16 ? Q OLB 1   C16 
220 1 N 1 A OLB 1216 ? C17 ? Q OLB 1   C17 
221 1 N 1 A OLB 1216 ? C18 ? Q OLB 1   C18 
222 1 N 1 A OLB 1217 ? C14 ? R OLB 1   C14 
223 1 N 1 A OLB 1217 ? C15 ? R OLB 1   C15 
224 1 N 1 A OLB 1217 ? C16 ? R OLB 1   C16 
225 1 N 1 A OLB 1217 ? C17 ? R OLB 1   C17 
226 1 N 1 A OLB 1217 ? C18 ? R OLB 1   C18 
227 1 N 1 A OLC 1219 ? C18 ? T OLC 1   C18 
228 1 N 1 A OLC 1219 ? C17 ? T OLC 1   C17 
229 1 N 1 A OLC 1219 ? C16 ? T OLC 1   C16 
230 1 N 1 A OLC 1219 ? C15 ? T OLC 1   C15 
231 1 N 1 A OLC 1219 ? C13 ? T OLC 1   C13 
232 1 N 1 A OLC 1219 ? C14 ? T OLC 1   C14 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.21_5207 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FUP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     40.170 
_cell.length_a_esd                 ? 
_cell.length_b                     179.400 
_cell.length_b_esd                 ? 
_cell.length_c                     142.430 
_cell.length_c_esd                 ? 
_cell.volume                       1026421.510 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FUP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FUP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.75 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'LIPIDIC CUBIC PHASE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'0.1 M tri-sodium citrate pH 5.0, 50 mM sodium thiocyanate, 29-30% (v/v) PEG 400, 1% (v/v) 1,6-hexanediol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'PSI JUNGFRAU 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-09-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.072 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID29' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.072 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID29 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          63.85 
_reflns.entry_id                                       9FUP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.50 
_reflns.d_resolution_low                               89.7 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     18404 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                208 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.33 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   0.9861 
_reflns.pdbx_R_split                                   0.2311 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.50 
_reflns_shell.d_res_low                                     2.54 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             796 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  0.5244 
_reflns_shell.pdbx_R_split                                  2.4647 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               80.53 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FUP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.50 
_refine.ls_d_res_low                             55.77 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     17921 
_refine.ls_number_reflns_R_free                  1808 
_refine.ls_number_reflns_R_work                  16113 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.48 
_refine.ls_percent_reflns_R_free                 10.09 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2548 
_refine.ls_R_factor_R_free                       0.2880 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2511 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.8784 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4316 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.50 
_refine_hist.d_res_low                        55.77 
_refine_hist.number_atoms_solvent             42 
_refine_hist.number_atoms_total               3195 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2806 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         347 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0022  ? 3221 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4680  ? 4357 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0331  ? 516  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0038  ? 521  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.4363 ? 1330 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.50 2.57  . . 128 1085 88.80  . . . . 0.3740 . . . . . . . . . . . 0.4260 
'X-RAY DIFFRACTION' 2.57 2.64  . . 129 1079 85.37  . . . . 0.3528 . . . . . . . . . . . 0.4119 
'X-RAY DIFFRACTION' 2.64 2.73  . . 132 1185 96.98  . . . . 0.3340 . . . . . . . . . . . 0.3465 
'X-RAY DIFFRACTION' 2.73 2.83  . . 137 1226 97.36  . . . . 0.3341 . . . . . . . . . . . 0.3212 
'X-RAY DIFFRACTION' 2.83 2.94  . . 138 1244 99.14  . . . . 0.3658 . . . . . . . . . . . 0.3991 
'X-RAY DIFFRACTION' 2.94 3.07  . . 140 1262 99.72  . . . . 0.2934 . . . . . . . . . . . 0.3595 
'X-RAY DIFFRACTION' 3.07 3.23  . . 138 1236 99.78  . . . . 0.2837 . . . . . . . . . . . 0.2886 
'X-RAY DIFFRACTION' 3.24 3.44  . . 141 1273 99.86  . . . . 0.2588 . . . . . . . . . . . 0.2875 
'X-RAY DIFFRACTION' 3.44 3.70  . . 142 1279 100.00 . . . . 0.2596 . . . . . . . . . . . 0.3192 
'X-RAY DIFFRACTION' 3.70 4.08  . . 142 1273 99.93  . . . . 0.2145 . . . . . . . . . . . 0.2510 
'X-RAY DIFFRACTION' 4.08 4.67  . . 142 1278 99.93  . . . . 0.1973 . . . . . . . . . . . 0.2296 
'X-RAY DIFFRACTION' 4.67 5.88  . . 146 1311 100.00 . . . . 0.2343 . . . . . . . . . . . 0.2675 
'X-RAY DIFFRACTION' 5.88 55.77 . . 153 1382 99.87  . . . . 0.2406 . . . . . . . . . . . 0.2838 
# 
_struct.entry_id                     9FUP 
_struct.title                        
;Serial microseconds crystallography at ID29 using fixed-target (small foils): A2a adenosine receptor co-crystallised with Istradefylline
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FUP 
_struct_keywords.text            
;Serial crystallography, serial microsecond crystallography, room temperature, ID29, ESRF-EBS, fixed-target, foils, membrane protein, A2A receptor, Istradefylline, SIGNALING PROTEIN
;
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
P N N 4 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 6 ? 
T N N 6 ? 
U N N 7 ? 
V N N 8 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP AA2AR_HUMAN P29274 ? 1 
;PIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIA
CFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGE
GQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQL
;
2   
2 UNP C562_ECOLX  P0ABE7 ? 1 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23  
3 UNP AA2AR_HUMAN P29274 ? 1 
;ERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQT
FRKIIRSHVLRQQEPFKAA
;
219 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FUP A 11  ? 217 ? P29274 2   ? 208 ? 2    208  
2 2 9FUP A 218 ? 322 ? P0ABE7 23  ? 127 ? 1001 1105 
3 3 9FUP A 324 ? 422 ? P29274 219 ? 317 ? 219  317  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FUP ASP A 1   ? UNP P29274 ?   ?   'expression tag' -8   1  
1 9FUP TYR A 2   ? UNP P29274 ?   ?   'expression tag' -7   2  
1 9FUP LYS A 3   ? UNP P29274 ?   ?   'expression tag' -6   3  
1 9FUP ASP A 4   ? UNP P29274 ?   ?   'expression tag' -5   4  
1 9FUP ASP A 5   ? UNP P29274 ?   ?   'expression tag' -4   5  
1 9FUP ASP A 6   ? UNP P29274 ?   ?   'expression tag' -3   6  
1 9FUP ASP A 7   ? UNP P29274 ?   ?   'expression tag' -2   7  
1 9FUP GLY A 8   ? UNP P29274 ?   ?   'expression tag' -1   8  
1 9FUP ALA A 9   ? UNP P29274 ?   ?   'expression tag' 0    9  
1 9FUP PRO A 10  ? UNP P29274 ?   ?   'expression tag' 1    10 
1 9FUP LEU A 63  ? UNP P29274 ALA 54  conflict         54   11 
1 9FUP ALA A 97  ? UNP P29274 THR 88  conflict         88   12 
1 9FUP ALA A 116 ? UNP P29274 ARG 107 conflict         107  13 
1 9FUP ALA A 131 ? UNP P29274 LYS 122 conflict         122  14 
1 9FUP ALA A 163 ? UNP P29274 ASN 154 conflict         154  15 
1 9FUP ALA A 211 ? UNP P29274 LEU 202 conflict         202  16 
2 9FUP TRP A 224 ? UNP P0ABE7 MET 29  conflict         1007 17 
2 9FUP ILE A 319 ? UNP P0ABE7 HIS 124 conflict         1102 18 
2 9FUP LEU A 323 ? UNP P0ABE7 ?   ?   linker           1106 19 
3 9FUP ALA A 340 ? UNP P29274 LEU 235 conflict         235  20 
3 9FUP ALA A 344 ? UNP P29274 VAL 239 conflict         239  21 
3 9FUP ALA A 382 ? UNP P29274 SER 277 conflict         277  22 
3 9FUP ALA A 423 ? UNP P29274 ?   ?   'expression tag' 318  23 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6720  ? 
1 MORE         14    ? 
1 'SSA (A^2)'  19070 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 10  ? ASN A 43  ? PRO A 1    ASN A 34   1 ? 34 
HELX_P HELX_P2  AA2 SER A 44  ? GLN A 47  ? SER A 35   GLN A 38   5 ? 4  
HELX_P HELX_P3  AA3 ASN A 48  ? LEU A 67  ? ASN A 39   LEU A 58   1 ? 20 
HELX_P HELX_P4  AA4 LEU A 67  ? THR A 77  ? LEU A 58   THR A 68   1 ? 11 
HELX_P HELX_P5  AA5 CYS A 83  ? ILE A 117 ? CYS A 74   ILE A 108  1 ? 35 
HELX_P HELX_P6  AA6 ARG A 120 ? VAL A 125 ? ARG A 111  VAL A 116  1 ? 6  
HELX_P HELX_P7  AA7 THR A 126 ? LEU A 146 ? THR A 117  LEU A 137  1 ? 21 
HELX_P HELX_P8  AA8 THR A 147 ? GLY A 151 ? THR A 138  GLY A 142  5 ? 5  
HELX_P HELX_P9  AA9 LYS A 159 ? GLN A 166 ? LYS A 150  GLN A 157  1 ? 8  
HELX_P HELX_P10 AB1 LEU A 176 ? VAL A 181 ? LEU A 167  VAL A 172  1 ? 6  
HELX_P HELX_P11 AB2 PRO A 182 ? TYR A 188 ? PRO A 173  TYR A 179  1 ? 7  
HELX_P HELX_P12 AB3 VAL A 195 ? ALA A 237 ? VAL A 186  ALA A 1020 1 ? 43 
HELX_P HELX_P13 AB4 ASN A 239 ? GLN A 258 ? ASN A 1022 GLN A 1041 1 ? 20 
HELX_P HELX_P14 AB5 GLY A 281 ? GLU A 298 ? GLY A 1064 GLU A 1081 1 ? 18 
HELX_P HELX_P15 AB6 LYS A 300 ? GLN A 310 ? LYS A 1083 GLN A 1093 1 ? 11 
HELX_P HELX_P16 AB7 GLN A 310 ? TYR A 318 ? GLN A 1093 TYR A 1101 1 ? 9  
HELX_P HELX_P17 AB8 TYR A 318 ? CYS A 364 ? TYR A 1101 CYS A 259  1 ? 47 
HELX_P HELX_P18 AB9 PRO A 371 ? ILE A 397 ? PRO A 266  ILE A 292  1 ? 27 
HELX_P HELX_P19 AC1 ILE A 397 ? SER A 410 ? ILE A 292  SER A 305  1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 80  SG  ? ? ? 1_555 A CYS 168 SG ? ? A CYS 71   A CYS 159  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? A CYS 83  SG  ? ? ? 1_555 A CYS 155 SG ? ? A CYS 74   A CYS 146  1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf3 disulf ? ? A CYS 86  SG  ? ? ? 1_555 A CYS 175 SG ? ? A CYS 77   A CYS 166  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf4 disulf ? ? A CYS 364 SG  ? ? ? 1_555 A CYS 367 SG ? ? A CYS 259  A CYS 262  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
metalc1 metalc ? ? A ASP 61  OD1 ? ? ? 1_555 B NA  .   NA ? ? A ASP 52   A NA  1201 1_555 ? ? ? ? ? ? ? 2.486 ? ? 
metalc2 metalc ? ? A SER 100 OG  ? ? ? 1_555 B NA  .   NA ? ? A SER 91   A NA  1201 1_555 ? ? ? ? ? ? ? 2.929 ? ? 
metalc3 metalc ? ? B NA  .   NA  ? ? ? 1_555 V HOH .   O  ? ? A NA  1201 A HOH 1305 1_555 ? ? ? ? ? ? ? 2.343 ? ? 
metalc4 metalc ? ? B NA  .   NA  ? ? ? 1_555 V HOH .   O  ? ? A NA  1201 A HOH 1312 1_555 ? ? ? ? ? ? ? 2.591 ? ? 
metalc5 metalc ? ? B NA  .   NA  ? ? ? 1_555 V HOH .   O  ? ? A NA  1201 A HOH 1334 1_555 ? ? ? ? ? ? ? 3.159 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 61  ? A ASP 52   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 OG ? A SER 100 ? A SER 91   ? 1_555 121.8 ? 
2  OD1 ? A ASP 61  ? A ASP 52   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1305 ? 1_555 80.5  ? 
3  OG  ? A SER 100 ? A SER 91   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1305 ? 1_555 51.0  ? 
4  OD1 ? A ASP 61  ? A ASP 52   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1312 ? 1_555 85.6  ? 
5  OG  ? A SER 100 ? A SER 91   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1312 ? 1_555 131.7 ? 
6  O   ? V HOH .   ? A HOH 1305 ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1312 ? 1_555 162.1 ? 
7  OD1 ? A ASP 61  ? A ASP 52   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1334 ? 1_555 86.0  ? 
8  OG  ? A SER 100 ? A SER 91   ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1334 ? 1_555 123.0 ? 
9  O   ? V HOH .   ? A HOH 1305 ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1334 ? 1_555 95.0  ? 
10 O   ? V HOH .   ? A HOH 1312 ? 1_555 NA ? B NA . ? A NA 1201 ? 1_555 O  ? V HOH .   ? A HOH 1334 ? 1_555 95.3  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 80  ? CYS A 168 ? CYS A 71  ? 1_555 CYS A 159 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 83  ? CYS A 155 ? CYS A 74  ? 1_555 CYS A 146 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 86  ? CYS A 175 ? CYS A 77  ? 1_555 CYS A 166 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS A 364 ? CYS A 367 ? CYS A 259 ? 1_555 CYS A 262 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 CYS A 80  ? ALA A 82  ? CYS A 71  ALA A 73  
AA1 2 GLN A 172 ? ALA A 174 ? GLN A 163 ALA A 165 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   ALA 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    81 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    ALA 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     72 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   VAL 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    173 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    VAL 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     164 
# 
_pdbx_entry_details.entry_id                   9FUP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O  A HOH 1303 ? ? O   A HOH 1327 ? ? 2.03 
2 1 OG A SER 6    ? ? O1  A OLA 1208 ? ? 2.12 
3 1 O  A HOH 1308 ? ? O   A HOH 1336 ? ? 2.13 
4 1 O  A ALA 1090 ? ? O   A HOH 1301 ? ? 2.14 
5 1 O  A VAL 1084 ? ? OE1 A GLN 1088 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 58   ? ? -123.33 -50.40 
2 1 TYR A 1101 ? ? -136.25 -46.22 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1341 ? 6.15 . 
2 1 O ? A HOH 1342 ? 9.91 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A ASP -8   ? A ASP 1   
2  1 Y 1 A TYR -7   ? A TYR 2   
3  1 Y 1 A LYS -6   ? A LYS 3   
4  1 Y 1 A ASP -5   ? A ASP 4   
5  1 Y 1 A ASP -4   ? A ASP 5   
6  1 Y 1 A ASP -3   ? A ASP 6   
7  1 Y 1 A ASP -2   ? A ASP 7   
8  1 Y 1 A GLY -1   ? A GLY 8   
9  1 Y 1 A THR 1044 ? A THR 261 
10 1 Y 1 A PRO 1045 ? A PRO 262 
11 1 Y 1 A PRO 1046 ? A PRO 263 
12 1 Y 1 A LYS 1047 ? A LYS 264 
13 1 Y 1 A LEU 1048 ? A LEU 265 
14 1 Y 1 A GLU 1049 ? A GLU 266 
15 1 Y 1 A ASP 1050 ? A ASP 267 
16 1 Y 1 A LYS 1051 ? A LYS 268 
17 1 Y 1 A SER 1052 ? A SER 269 
18 1 Y 1 A PRO 1053 ? A PRO 270 
19 1 Y 1 A ASP 1054 ? A ASP 271 
20 1 Y 1 A SER 1055 ? A SER 272 
21 1 Y 1 A PRO 1056 ? A PRO 273 
22 1 Y 1 A GLU 1057 ? A GLU 274 
23 1 Y 1 A MET 1058 ? A MET 275 
24 1 Y 1 A LYS 1059 ? A LYS 276 
25 1 Y 1 A ASP 1060 ? A ASP 277 
26 1 Y 1 A PHE 1061 ? A PHE 278 
27 1 Y 1 A ARG 1062 ? A ARG 279 
28 1 Y 1 A HIS 306  ? A HIS 411 
29 1 Y 1 A VAL 307  ? A VAL 412 
30 1 Y 1 A LEU 308  ? A LEU 413 
31 1 Y 1 A ARG 309  ? A ARG 414 
32 1 Y 1 A GLN 310  ? A GLN 415 
33 1 Y 1 A GLN 311  ? A GLN 416 
34 1 Y 1 A GLU 312  ? A GLU 417 
35 1 Y 1 A PRO 313  ? A PRO 418 
36 1 Y 1 A PHE 314  ? A PHE 419 
37 1 Y 1 A LYS 315  ? A LYS 420 
38 1 Y 1 A ALA 316  ? A ALA 421 
39 1 Y 1 A ALA 317  ? A ALA 422 
40 1 Y 1 A ALA 318  ? A ALA 423 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N     N  N N 1   
ALA CA    C  N S 2   
ALA C     C  N N 3   
ALA O     O  N N 4   
ALA CB    C  N N 5   
ALA OXT   O  N N 6   
ALA H     H  N N 7   
ALA H2    H  N N 8   
ALA HA    H  N N 9   
ALA HB1   H  N N 10  
ALA HB2   H  N N 11  
ALA HB3   H  N N 12  
ALA HXT   H  N N 13  
ARG N     N  N N 14  
ARG CA    C  N S 15  
ARG C     C  N N 16  
ARG O     O  N N 17  
ARG CB    C  N N 18  
ARG CG    C  N N 19  
ARG CD    C  N N 20  
ARG NE    N  N N 21  
ARG CZ    C  N N 22  
ARG NH1   N  N N 23  
ARG NH2   N  N N 24  
ARG OXT   O  N N 25  
ARG H     H  N N 26  
ARG H2    H  N N 27  
ARG HA    H  N N 28  
ARG HB2   H  N N 29  
ARG HB3   H  N N 30  
ARG HG2   H  N N 31  
ARG HG3   H  N N 32  
ARG HD2   H  N N 33  
ARG HD3   H  N N 34  
ARG HE    H  N N 35  
ARG HH11  H  N N 36  
ARG HH12  H  N N 37  
ARG HH21  H  N N 38  
ARG HH22  H  N N 39  
ARG HXT   H  N N 40  
ASN N     N  N N 41  
ASN CA    C  N S 42  
ASN C     C  N N 43  
ASN O     O  N N 44  
ASN CB    C  N N 45  
ASN CG    C  N N 46  
ASN OD1   O  N N 47  
ASN ND2   N  N N 48  
ASN OXT   O  N N 49  
ASN H     H  N N 50  
ASN H2    H  N N 51  
ASN HA    H  N N 52  
ASN HB2   H  N N 53  
ASN HB3   H  N N 54  
ASN HD21  H  N N 55  
ASN HD22  H  N N 56  
ASN HXT   H  N N 57  
ASP N     N  N N 58  
ASP CA    C  N S 59  
ASP C     C  N N 60  
ASP O     O  N N 61  
ASP CB    C  N N 62  
ASP CG    C  N N 63  
ASP OD1   O  N N 64  
ASP OD2   O  N N 65  
ASP OXT   O  N N 66  
ASP H     H  N N 67  
ASP H2    H  N N 68  
ASP HA    H  N N 69  
ASP HB2   H  N N 70  
ASP HB3   H  N N 71  
ASP HD2   H  N N 72  
ASP HXT   H  N N 73  
CLR C1    C  N N 74  
CLR C2    C  N N 75  
CLR C3    C  N S 76  
CLR C4    C  N N 77  
CLR C5    C  N N 78  
CLR C6    C  N N 79  
CLR C7    C  N N 80  
CLR C8    C  N S 81  
CLR C9    C  N S 82  
CLR C10   C  N R 83  
CLR C11   C  N N 84  
CLR C12   C  N N 85  
CLR C13   C  N R 86  
CLR C14   C  N S 87  
CLR C15   C  N N 88  
CLR C16   C  N N 89  
CLR C17   C  N R 90  
CLR C18   C  N N 91  
CLR C19   C  N N 92  
CLR C20   C  N R 93  
CLR C21   C  N N 94  
CLR C22   C  N N 95  
CLR C23   C  N N 96  
CLR C24   C  N N 97  
CLR C25   C  N N 98  
CLR C26   C  N N 99  
CLR C27   C  N N 100 
CLR O1    O  N N 101 
CLR H11   H  N N 102 
CLR H12   H  N N 103 
CLR H21   H  N N 104 
CLR H22   H  N N 105 
CLR H3    H  N N 106 
CLR H41   H  N N 107 
CLR H42   H  N N 108 
CLR H6    H  N N 109 
CLR H71   H  N N 110 
CLR H72   H  N N 111 
CLR H8    H  N N 112 
CLR H9    H  N N 113 
CLR H111  H  N N 114 
CLR H112  H  N N 115 
CLR H121  H  N N 116 
CLR H122  H  N N 117 
CLR H14   H  N N 118 
CLR H151  H  N N 119 
CLR H152  H  N N 120 
CLR H161  H  N N 121 
CLR H162  H  N N 122 
CLR H17   H  N N 123 
CLR H181  H  N N 124 
CLR H182  H  N N 125 
CLR H183  H  N N 126 
CLR H191  H  N N 127 
CLR H192  H  N N 128 
CLR H193  H  N N 129 
CLR H20   H  N N 130 
CLR H211  H  N N 131 
CLR H212  H  N N 132 
CLR H213  H  N N 133 
CLR H221  H  N N 134 
CLR H222  H  N N 135 
CLR H231  H  N N 136 
CLR H232  H  N N 137 
CLR H241  H  N N 138 
CLR H242  H  N N 139 
CLR H25   H  N N 140 
CLR H261  H  N N 141 
CLR H262  H  N N 142 
CLR H263  H  N N 143 
CLR H271  H  N N 144 
CLR H272  H  N N 145 
CLR H273  H  N N 146 
CLR H1    H  N N 147 
CYS N     N  N N 148 
CYS CA    C  N R 149 
CYS C     C  N N 150 
CYS O     O  N N 151 
CYS CB    C  N N 152 
CYS SG    S  N N 153 
CYS OXT   O  N N 154 
CYS H     H  N N 155 
CYS H2    H  N N 156 
CYS HA    H  N N 157 
CYS HB2   H  N N 158 
CYS HB3   H  N N 159 
CYS HG    H  N N 160 
CYS HXT   H  N N 161 
GLN N     N  N N 162 
GLN CA    C  N S 163 
GLN C     C  N N 164 
GLN O     O  N N 165 
GLN CB    C  N N 166 
GLN CG    C  N N 167 
GLN CD    C  N N 168 
GLN OE1   O  N N 169 
GLN NE2   N  N N 170 
GLN OXT   O  N N 171 
GLN H     H  N N 172 
GLN H2    H  N N 173 
GLN HA    H  N N 174 
GLN HB2   H  N N 175 
GLN HB3   H  N N 176 
GLN HG2   H  N N 177 
GLN HG3   H  N N 178 
GLN HE21  H  N N 179 
GLN HE22  H  N N 180 
GLN HXT   H  N N 181 
GLU N     N  N N 182 
GLU CA    C  N S 183 
GLU C     C  N N 184 
GLU O     O  N N 185 
GLU CB    C  N N 186 
GLU CG    C  N N 187 
GLU CD    C  N N 188 
GLU OE1   O  N N 189 
GLU OE2   O  N N 190 
GLU OXT   O  N N 191 
GLU H     H  N N 192 
GLU H2    H  N N 193 
GLU HA    H  N N 194 
GLU HB2   H  N N 195 
GLU HB3   H  N N 196 
GLU HG2   H  N N 197 
GLU HG3   H  N N 198 
GLU HE2   H  N N 199 
GLU HXT   H  N N 200 
GLY N     N  N N 201 
GLY CA    C  N N 202 
GLY C     C  N N 203 
GLY O     O  N N 204 
GLY OXT   O  N N 205 
GLY H     H  N N 206 
GLY H2    H  N N 207 
GLY HA2   H  N N 208 
GLY HA3   H  N N 209 
GLY HXT   H  N N 210 
HIS N     N  N N 211 
HIS CA    C  N S 212 
HIS C     C  N N 213 
HIS O     O  N N 214 
HIS CB    C  N N 215 
HIS CG    C  Y N 216 
HIS ND1   N  Y N 217 
HIS CD2   C  Y N 218 
HIS CE1   C  Y N 219 
HIS NE2   N  Y N 220 
HIS OXT   O  N N 221 
HIS H     H  N N 222 
HIS H2    H  N N 223 
HIS HA    H  N N 224 
HIS HB2   H  N N 225 
HIS HB3   H  N N 226 
HIS HD1   H  N N 227 
HIS HD2   H  N N 228 
HIS HE1   H  N N 229 
HIS HE2   H  N N 230 
HIS HXT   H  N N 231 
HOH O     O  N N 232 
HOH H1    H  N N 233 
HOH H2    H  N N 234 
ILE N     N  N N 235 
ILE CA    C  N S 236 
ILE C     C  N N 237 
ILE O     O  N N 238 
ILE CB    C  N S 239 
ILE CG1   C  N N 240 
ILE CG2   C  N N 241 
ILE CD1   C  N N 242 
ILE OXT   O  N N 243 
ILE H     H  N N 244 
ILE H2    H  N N 245 
ILE HA    H  N N 246 
ILE HB    H  N N 247 
ILE HG12  H  N N 248 
ILE HG13  H  N N 249 
ILE HG21  H  N N 250 
ILE HG22  H  N N 251 
ILE HG23  H  N N 252 
ILE HD11  H  N N 253 
ILE HD12  H  N N 254 
ILE HD13  H  N N 255 
ILE HXT   H  N N 256 
JQ9 N1    N  N N 257 
JQ9 C12   C  N N 258 
JQ9 O2    O  N N 259 
JQ9 C2    C  N N 260 
JQ9 N3    N  N N 261 
JQ9 C21   C  N N 262 
JQ9 C22   C  N N 263 
JQ9 C4    C  Y N 264 
JQ9 N9    N  Y N 265 
JQ9 C8    C  Y N 266 
JQ9 N7    N  Y N 267 
JQ9 C7    C  N N 268 
JQ9 C5    C  Y N 269 
JQ9 C6    C  N N 270 
JQ9 O6    O  N N 271 
JQ9 C11   C  N N 272 
JQ9 CA    C  N N 273 
JQ9 CB    C  N N 274 
JQ9 "C1'" C  Y N 275 
JQ9 "C6'" C  Y N 276 
JQ9 "C5'" C  Y N 277 
JQ9 "C4'" C  Y N 278 
JQ9 "O4'" O  N N 279 
JQ9 "C8'" C  N N 280 
JQ9 "C3'" C  Y N 281 
JQ9 "C2'" C  Y N 282 
JQ9 "O3'" O  N N 283 
JQ9 "C9'" C  N N 284 
JQ9 H1    H  N N 285 
JQ9 H2    H  N N 286 
JQ9 H3    H  N N 287 
JQ9 H4    H  N N 288 
JQ9 H5    H  N N 289 
JQ9 H6    H  N N 290 
JQ9 H7    H  N N 291 
JQ9 H8    H  N N 292 
JQ9 H9    H  N N 293 
JQ9 H10   H  N N 294 
JQ9 H11   H  N N 295 
JQ9 H12   H  N N 296 
JQ9 H13   H  N N 297 
JQ9 H14   H  N N 298 
JQ9 H15   H  N N 299 
JQ9 H16   H  N N 300 
JQ9 H17   H  N N 301 
JQ9 H18   H  N N 302 
JQ9 H19   H  N N 303 
JQ9 H20   H  N N 304 
JQ9 H21   H  N N 305 
JQ9 H22   H  N N 306 
JQ9 H23   H  N N 307 
JQ9 H24   H  N N 308 
LEU N     N  N N 309 
LEU CA    C  N S 310 
LEU C     C  N N 311 
LEU O     O  N N 312 
LEU CB    C  N N 313 
LEU CG    C  N N 314 
LEU CD1   C  N N 315 
LEU CD2   C  N N 316 
LEU OXT   O  N N 317 
LEU H     H  N N 318 
LEU H2    H  N N 319 
LEU HA    H  N N 320 
LEU HB2   H  N N 321 
LEU HB3   H  N N 322 
LEU HG    H  N N 323 
LEU HD11  H  N N 324 
LEU HD12  H  N N 325 
LEU HD13  H  N N 326 
LEU HD21  H  N N 327 
LEU HD22  H  N N 328 
LEU HD23  H  N N 329 
LEU HXT   H  N N 330 
LYS N     N  N N 331 
LYS CA    C  N S 332 
LYS C     C  N N 333 
LYS O     O  N N 334 
LYS CB    C  N N 335 
LYS CG    C  N N 336 
LYS CD    C  N N 337 
LYS CE    C  N N 338 
LYS NZ    N  N N 339 
LYS OXT   O  N N 340 
LYS H     H  N N 341 
LYS H2    H  N N 342 
LYS HA    H  N N 343 
LYS HB2   H  N N 344 
LYS HB3   H  N N 345 
LYS HG2   H  N N 346 
LYS HG3   H  N N 347 
LYS HD2   H  N N 348 
LYS HD3   H  N N 349 
LYS HE2   H  N N 350 
LYS HE3   H  N N 351 
LYS HZ1   H  N N 352 
LYS HZ2   H  N N 353 
LYS HZ3   H  N N 354 
LYS HXT   H  N N 355 
MET N     N  N N 356 
MET CA    C  N S 357 
MET C     C  N N 358 
MET O     O  N N 359 
MET CB    C  N N 360 
MET CG    C  N N 361 
MET SD    S  N N 362 
MET CE    C  N N 363 
MET OXT   O  N N 364 
MET H     H  N N 365 
MET H2    H  N N 366 
MET HA    H  N N 367 
MET HB2   H  N N 368 
MET HB3   H  N N 369 
MET HG2   H  N N 370 
MET HG3   H  N N 371 
MET HE1   H  N N 372 
MET HE2   H  N N 373 
MET HE3   H  N N 374 
MET HXT   H  N N 375 
NA  NA    NA N N 376 
OLA C1    C  N N 377 
OLA O1    O  N N 378 
OLA O2    O  N N 379 
OLA C2    C  N N 380 
OLA C3    C  N N 381 
OLA C4    C  N N 382 
OLA C5    C  N N 383 
OLA C6    C  N N 384 
OLA C7    C  N N 385 
OLA C8    C  N N 386 
OLA C9    C  N N 387 
OLA C10   C  N N 388 
OLA C11   C  N N 389 
OLA C12   C  N N 390 
OLA C13   C  N N 391 
OLA C14   C  N N 392 
OLA C15   C  N N 393 
OLA C16   C  N N 394 
OLA C17   C  N N 395 
OLA C18   C  N N 396 
OLA HO2   H  N N 397 
OLA H21   H  N N 398 
OLA H22   H  N N 399 
OLA H31   H  N N 400 
OLA H32   H  N N 401 
OLA H41   H  N N 402 
OLA H42   H  N N 403 
OLA H51   H  N N 404 
OLA H52   H  N N 405 
OLA H61   H  N N 406 
OLA H62   H  N N 407 
OLA H71   H  N N 408 
OLA H72   H  N N 409 
OLA H81   H  N N 410 
OLA H82   H  N N 411 
OLA H9    H  N N 412 
OLA H10   H  N N 413 
OLA H111  H  N N 414 
OLA H112  H  N N 415 
OLA H121  H  N N 416 
OLA H122  H  N N 417 
OLA H131  H  N N 418 
OLA H132  H  N N 419 
OLA H141  H  N N 420 
OLA H142  H  N N 421 
OLA H151  H  N N 422 
OLA H152  H  N N 423 
OLA H161  H  N N 424 
OLA H162  H  N N 425 
OLA H171  H  N N 426 
OLA H172  H  N N 427 
OLA H181  H  N N 428 
OLA H182  H  N N 429 
OLA H183  H  N N 430 
OLB C1    C  N N 431 
OLB C2    C  N N 432 
OLB C3    C  N N 433 
OLB C4    C  N N 434 
OLB C5    C  N N 435 
OLB O19   O  N N 436 
OLB O20   O  N N 437 
OLB C21   C  N N 438 
OLB C22   C  N S 439 
OLB O23   O  N N 440 
OLB C24   C  N N 441 
OLB O25   O  N N 442 
OLB C6    C  N N 443 
OLB C7    C  N N 444 
OLB C8    C  N N 445 
OLB C9    C  N N 446 
OLB C10   C  N N 447 
OLB C11   C  N N 448 
OLB H2    H  N N 449 
OLB H2A   H  N N 450 
OLB H3    H  N N 451 
OLB H3A   H  N N 452 
OLB H4    H  N N 453 
OLB H4A   H  N N 454 
OLB H5    H  N N 455 
OLB H5A   H  N N 456 
OLB H21   H  N N 457 
OLB H21A  H  N N 458 
OLB H22   H  N N 459 
OLB HO23  H  N N 460 
OLB H24   H  N N 461 
OLB H24A  H  N N 462 
OLB HO25  H  N N 463 
OLB H16   H  N N 464 
OLB H17   H  N N 465 
OLB H18   H  N N 466 
OLB H19   H  N N 467 
OLB H20   H  N N 468 
OLB H211  H  N N 469 
OLB H221  H  N N 470 
OLB H23   H  N N 471 
OLB H241  H  N N 472 
OLB H25   H  N N 473 
OLB C12   C  N N 474 
OLB H26   H  N N 475 
OLB C13   C  N N 476 
OLB H27   H  N N 477 
OLB C14   C  N N 478 
OLB H28   H  N N 479 
OLB H29   H  N N 480 
OLB H30   H  N N 481 
OLB H31   H  N N 482 
OLB C15   C  N N 483 
OLB C16   C  N N 484 
OLB H32   H  N N 485 
OLB H33   H  N N 486 
OLB H34   H  N N 487 
OLB H35   H  N N 488 
OLB C17   C  N N 489 
OLB C18   C  N N 490 
OLB H36   H  N N 491 
OLB H37   H  N N 492 
OLB H38   H  N N 493 
OLB H39   H  N N 494 
OLB H40   H  N N 495 
OLC C18   C  N N 496 
OLC C10   C  N N 497 
OLC C9    C  N N 498 
OLC C17   C  N N 499 
OLC C11   C  N N 500 
OLC C8    C  N N 501 
OLC C24   C  N N 502 
OLC C16   C  N N 503 
OLC C12   C  N N 504 
OLC C7    C  N N 505 
OLC C15   C  N N 506 
OLC C13   C  N N 507 
OLC C6    C  N N 508 
OLC C14   C  N N 509 
OLC C5    C  N N 510 
OLC C4    C  N N 511 
OLC C3    C  N N 512 
OLC C2    C  N N 513 
OLC C21   C  N N 514 
OLC C1    C  N N 515 
OLC C22   C  N R 516 
OLC O19   O  N N 517 
OLC O25   O  N N 518 
OLC O23   O  N N 519 
OLC O20   O  N N 520 
OLC H18   H  N N 521 
OLC H18A  H  N N 522 
OLC H18B  H  N N 523 
OLC H10   H  N N 524 
OLC H9    H  N N 525 
OLC H17   H  N N 526 
OLC H17A  H  N N 527 
OLC H11   H  N N 528 
OLC H11A  H  N N 529 
OLC H8    H  N N 530 
OLC H8A   H  N N 531 
OLC H24   H  N N 532 
OLC H24A  H  N N 533 
OLC H16   H  N N 534 
OLC H16A  H  N N 535 
OLC H12   H  N N 536 
OLC H12A  H  N N 537 
OLC H7    H  N N 538 
OLC H7A   H  N N 539 
OLC H15   H  N N 540 
OLC H15A  H  N N 541 
OLC H13   H  N N 542 
OLC H13A  H  N N 543 
OLC H6    H  N N 544 
OLC H6A   H  N N 545 
OLC H14   H  N N 546 
OLC H14A  H  N N 547 
OLC H5    H  N N 548 
OLC H5A   H  N N 549 
OLC H4    H  N N 550 
OLC H4A   H  N N 551 
OLC H3    H  N N 552 
OLC H3A   H  N N 553 
OLC H2    H  N N 554 
OLC H2A   H  N N 555 
OLC H21   H  N N 556 
OLC H21A  H  N N 557 
OLC H22   H  N N 558 
OLC HO25  H  N N 559 
OLC HO23  H  N N 560 
PHE N     N  N N 561 
PHE CA    C  N S 562 
PHE C     C  N N 563 
PHE O     O  N N 564 
PHE CB    C  N N 565 
PHE CG    C  Y N 566 
PHE CD1   C  Y N 567 
PHE CD2   C  Y N 568 
PHE CE1   C  Y N 569 
PHE CE2   C  Y N 570 
PHE CZ    C  Y N 571 
PHE OXT   O  N N 572 
PHE H     H  N N 573 
PHE H2    H  N N 574 
PHE HA    H  N N 575 
PHE HB2   H  N N 576 
PHE HB3   H  N N 577 
PHE HD1   H  N N 578 
PHE HD2   H  N N 579 
PHE HE1   H  N N 580 
PHE HE2   H  N N 581 
PHE HZ    H  N N 582 
PHE HXT   H  N N 583 
PRO N     N  N N 584 
PRO CA    C  N S 585 
PRO C     C  N N 586 
PRO O     O  N N 587 
PRO CB    C  N N 588 
PRO CG    C  N N 589 
PRO CD    C  N N 590 
PRO OXT   O  N N 591 
PRO H     H  N N 592 
PRO HA    H  N N 593 
PRO HB2   H  N N 594 
PRO HB3   H  N N 595 
PRO HG2   H  N N 596 
PRO HG3   H  N N 597 
PRO HD2   H  N N 598 
PRO HD3   H  N N 599 
PRO HXT   H  N N 600 
SER N     N  N N 601 
SER CA    C  N S 602 
SER C     C  N N 603 
SER O     O  N N 604 
SER CB    C  N N 605 
SER OG    O  N N 606 
SER OXT   O  N N 607 
SER H     H  N N 608 
SER H2    H  N N 609 
SER HA    H  N N 610 
SER HB2   H  N N 611 
SER HB3   H  N N 612 
SER HG    H  N N 613 
SER HXT   H  N N 614 
THR N     N  N N 615 
THR CA    C  N S 616 
THR C     C  N N 617 
THR O     O  N N 618 
THR CB    C  N R 619 
THR OG1   O  N N 620 
THR CG2   C  N N 621 
THR OXT   O  N N 622 
THR H     H  N N 623 
THR H2    H  N N 624 
THR HA    H  N N 625 
THR HB    H  N N 626 
THR HG1   H  N N 627 
THR HG21  H  N N 628 
THR HG22  H  N N 629 
THR HG23  H  N N 630 
THR HXT   H  N N 631 
TRP N     N  N N 632 
TRP CA    C  N S 633 
TRP C     C  N N 634 
TRP O     O  N N 635 
TRP CB    C  N N 636 
TRP CG    C  Y N 637 
TRP CD1   C  Y N 638 
TRP CD2   C  Y N 639 
TRP NE1   N  Y N 640 
TRP CE2   C  Y N 641 
TRP CE3   C  Y N 642 
TRP CZ2   C  Y N 643 
TRP CZ3   C  Y N 644 
TRP CH2   C  Y N 645 
TRP OXT   O  N N 646 
TRP H     H  N N 647 
TRP H2    H  N N 648 
TRP HA    H  N N 649 
TRP HB2   H  N N 650 
TRP HB3   H  N N 651 
TRP HD1   H  N N 652 
TRP HE1   H  N N 653 
TRP HE3   H  N N 654 
TRP HZ2   H  N N 655 
TRP HZ3   H  N N 656 
TRP HH2   H  N N 657 
TRP HXT   H  N N 658 
TYR N     N  N N 659 
TYR CA    C  N S 660 
TYR C     C  N N 661 
TYR O     O  N N 662 
TYR CB    C  N N 663 
TYR CG    C  Y N 664 
TYR CD1   C  Y N 665 
TYR CD2   C  Y N 666 
TYR CE1   C  Y N 667 
TYR CE2   C  Y N 668 
TYR CZ    C  Y N 669 
TYR OH    O  N N 670 
TYR OXT   O  N N 671 
TYR H     H  N N 672 
TYR H2    H  N N 673 
TYR HA    H  N N 674 
TYR HB2   H  N N 675 
TYR HB3   H  N N 676 
TYR HD1   H  N N 677 
TYR HD2   H  N N 678 
TYR HE1   H  N N 679 
TYR HE2   H  N N 680 
TYR HH    H  N N 681 
TYR HXT   H  N N 682 
VAL N     N  N N 683 
VAL CA    C  N S 684 
VAL C     C  N N 685 
VAL O     O  N N 686 
VAL CB    C  N N 687 
VAL CG1   C  N N 688 
VAL CG2   C  N N 689 
VAL OXT   O  N N 690 
VAL H     H  N N 691 
VAL H2    H  N N 692 
VAL HA    H  N N 693 
VAL HB    H  N N 694 
VAL HG11  H  N N 695 
VAL HG12  H  N N 696 
VAL HG13  H  N N 697 
VAL HG21  H  N N 698 
VAL HG22  H  N N 699 
VAL HG23  H  N N 700 
VAL HXT   H  N N 701 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA    sing N N 1   
ALA N     H     sing N N 2   
ALA N     H2    sing N N 3   
ALA CA    C     sing N N 4   
ALA CA    CB    sing N N 5   
ALA CA    HA    sing N N 6   
ALA C     O     doub N N 7   
ALA C     OXT   sing N N 8   
ALA CB    HB1   sing N N 9   
ALA CB    HB2   sing N N 10  
ALA CB    HB3   sing N N 11  
ALA OXT   HXT   sing N N 12  
ARG N     CA    sing N N 13  
ARG N     H     sing N N 14  
ARG N     H2    sing N N 15  
ARG CA    C     sing N N 16  
ARG CA    CB    sing N N 17  
ARG CA    HA    sing N N 18  
ARG C     O     doub N N 19  
ARG C     OXT   sing N N 20  
ARG CB    CG    sing N N 21  
ARG CB    HB2   sing N N 22  
ARG CB    HB3   sing N N 23  
ARG CG    CD    sing N N 24  
ARG CG    HG2   sing N N 25  
ARG CG    HG3   sing N N 26  
ARG CD    NE    sing N N 27  
ARG CD    HD2   sing N N 28  
ARG CD    HD3   sing N N 29  
ARG NE    CZ    sing N N 30  
ARG NE    HE    sing N N 31  
ARG CZ    NH1   sing N N 32  
ARG CZ    NH2   doub N N 33  
ARG NH1   HH11  sing N N 34  
ARG NH1   HH12  sing N N 35  
ARG NH2   HH21  sing N N 36  
ARG NH2   HH22  sing N N 37  
ARG OXT   HXT   sing N N 38  
ASN N     CA    sing N N 39  
ASN N     H     sing N N 40  
ASN N     H2    sing N N 41  
ASN CA    C     sing N N 42  
ASN CA    CB    sing N N 43  
ASN CA    HA    sing N N 44  
ASN C     O     doub N N 45  
ASN C     OXT   sing N N 46  
ASN CB    CG    sing N N 47  
ASN CB    HB2   sing N N 48  
ASN CB    HB3   sing N N 49  
ASN CG    OD1   doub N N 50  
ASN CG    ND2   sing N N 51  
ASN ND2   HD21  sing N N 52  
ASN ND2   HD22  sing N N 53  
ASN OXT   HXT   sing N N 54  
ASP N     CA    sing N N 55  
ASP N     H     sing N N 56  
ASP N     H2    sing N N 57  
ASP CA    C     sing N N 58  
ASP CA    CB    sing N N 59  
ASP CA    HA    sing N N 60  
ASP C     O     doub N N 61  
ASP C     OXT   sing N N 62  
ASP CB    CG    sing N N 63  
ASP CB    HB2   sing N N 64  
ASP CB    HB3   sing N N 65  
ASP CG    OD1   doub N N 66  
ASP CG    OD2   sing N N 67  
ASP OD2   HD2   sing N N 68  
ASP OXT   HXT   sing N N 69  
CLR C1    C2    sing N N 70  
CLR C1    C10   sing N N 71  
CLR C1    H11   sing N N 72  
CLR C1    H12   sing N N 73  
CLR C2    C3    sing N N 74  
CLR C2    H21   sing N N 75  
CLR C2    H22   sing N N 76  
CLR C3    C4    sing N N 77  
CLR C3    O1    sing N N 78  
CLR C3    H3    sing N N 79  
CLR C4    C5    sing N N 80  
CLR C4    H41   sing N N 81  
CLR C4    H42   sing N N 82  
CLR C5    C6    doub N N 83  
CLR C5    C10   sing N N 84  
CLR C6    C7    sing N N 85  
CLR C6    H6    sing N N 86  
CLR C7    C8    sing N N 87  
CLR C7    H71   sing N N 88  
CLR C7    H72   sing N N 89  
CLR C8    C9    sing N N 90  
CLR C8    C14   sing N N 91  
CLR C8    H8    sing N N 92  
CLR C9    C10   sing N N 93  
CLR C9    C11   sing N N 94  
CLR C9    H9    sing N N 95  
CLR C10   C19   sing N N 96  
CLR C11   C12   sing N N 97  
CLR C11   H111  sing N N 98  
CLR C11   H112  sing N N 99  
CLR C12   C13   sing N N 100 
CLR C12   H121  sing N N 101 
CLR C12   H122  sing N N 102 
CLR C13   C14   sing N N 103 
CLR C13   C17   sing N N 104 
CLR C13   C18   sing N N 105 
CLR C14   C15   sing N N 106 
CLR C14   H14   sing N N 107 
CLR C15   C16   sing N N 108 
CLR C15   H151  sing N N 109 
CLR C15   H152  sing N N 110 
CLR C16   C17   sing N N 111 
CLR C16   H161  sing N N 112 
CLR C16   H162  sing N N 113 
CLR C17   C20   sing N N 114 
CLR C17   H17   sing N N 115 
CLR C18   H181  sing N N 116 
CLR C18   H182  sing N N 117 
CLR C18   H183  sing N N 118 
CLR C19   H191  sing N N 119 
CLR C19   H192  sing N N 120 
CLR C19   H193  sing N N 121 
CLR C20   C21   sing N N 122 
CLR C20   C22   sing N N 123 
CLR C20   H20   sing N N 124 
CLR C21   H211  sing N N 125 
CLR C21   H212  sing N N 126 
CLR C21   H213  sing N N 127 
CLR C22   C23   sing N N 128 
CLR C22   H221  sing N N 129 
CLR C22   H222  sing N N 130 
CLR C23   C24   sing N N 131 
CLR C23   H231  sing N N 132 
CLR C23   H232  sing N N 133 
CLR C24   C25   sing N N 134 
CLR C24   H241  sing N N 135 
CLR C24   H242  sing N N 136 
CLR C25   C26   sing N N 137 
CLR C25   C27   sing N N 138 
CLR C25   H25   sing N N 139 
CLR C26   H261  sing N N 140 
CLR C26   H262  sing N N 141 
CLR C26   H263  sing N N 142 
CLR C27   H271  sing N N 143 
CLR C27   H272  sing N N 144 
CLR C27   H273  sing N N 145 
CLR O1    H1    sing N N 146 
CYS N     CA    sing N N 147 
CYS N     H     sing N N 148 
CYS N     H2    sing N N 149 
CYS CA    C     sing N N 150 
CYS CA    CB    sing N N 151 
CYS CA    HA    sing N N 152 
CYS C     O     doub N N 153 
CYS C     OXT   sing N N 154 
CYS CB    SG    sing N N 155 
CYS CB    HB2   sing N N 156 
CYS CB    HB3   sing N N 157 
CYS SG    HG    sing N N 158 
CYS OXT   HXT   sing N N 159 
GLN N     CA    sing N N 160 
GLN N     H     sing N N 161 
GLN N     H2    sing N N 162 
GLN CA    C     sing N N 163 
GLN CA    CB    sing N N 164 
GLN CA    HA    sing N N 165 
GLN C     O     doub N N 166 
GLN C     OXT   sing N N 167 
GLN CB    CG    sing N N 168 
GLN CB    HB2   sing N N 169 
GLN CB    HB3   sing N N 170 
GLN CG    CD    sing N N 171 
GLN CG    HG2   sing N N 172 
GLN CG    HG3   sing N N 173 
GLN CD    OE1   doub N N 174 
GLN CD    NE2   sing N N 175 
GLN NE2   HE21  sing N N 176 
GLN NE2   HE22  sing N N 177 
GLN OXT   HXT   sing N N 178 
GLU N     CA    sing N N 179 
GLU N     H     sing N N 180 
GLU N     H2    sing N N 181 
GLU CA    C     sing N N 182 
GLU CA    CB    sing N N 183 
GLU CA    HA    sing N N 184 
GLU C     O     doub N N 185 
GLU C     OXT   sing N N 186 
GLU CB    CG    sing N N 187 
GLU CB    HB2   sing N N 188 
GLU CB    HB3   sing N N 189 
GLU CG    CD    sing N N 190 
GLU CG    HG2   sing N N 191 
GLU CG    HG3   sing N N 192 
GLU CD    OE1   doub N N 193 
GLU CD    OE2   sing N N 194 
GLU OE2   HE2   sing N N 195 
GLU OXT   HXT   sing N N 196 
GLY N     CA    sing N N 197 
GLY N     H     sing N N 198 
GLY N     H2    sing N N 199 
GLY CA    C     sing N N 200 
GLY CA    HA2   sing N N 201 
GLY CA    HA3   sing N N 202 
GLY C     O     doub N N 203 
GLY C     OXT   sing N N 204 
GLY OXT   HXT   sing N N 205 
HIS N     CA    sing N N 206 
HIS N     H     sing N N 207 
HIS N     H2    sing N N 208 
HIS CA    C     sing N N 209 
HIS CA    CB    sing N N 210 
HIS CA    HA    sing N N 211 
HIS C     O     doub N N 212 
HIS C     OXT   sing N N 213 
HIS CB    CG    sing N N 214 
HIS CB    HB2   sing N N 215 
HIS CB    HB3   sing N N 216 
HIS CG    ND1   sing Y N 217 
HIS CG    CD2   doub Y N 218 
HIS ND1   CE1   doub Y N 219 
HIS ND1   HD1   sing N N 220 
HIS CD2   NE2   sing Y N 221 
HIS CD2   HD2   sing N N 222 
HIS CE1   NE2   sing Y N 223 
HIS CE1   HE1   sing N N 224 
HIS NE2   HE2   sing N N 225 
HIS OXT   HXT   sing N N 226 
HOH O     H1    sing N N 227 
HOH O     H2    sing N N 228 
ILE N     CA    sing N N 229 
ILE N     H     sing N N 230 
ILE N     H2    sing N N 231 
ILE CA    C     sing N N 232 
ILE CA    CB    sing N N 233 
ILE CA    HA    sing N N 234 
ILE C     O     doub N N 235 
ILE C     OXT   sing N N 236 
ILE CB    CG1   sing N N 237 
ILE CB    CG2   sing N N 238 
ILE CB    HB    sing N N 239 
ILE CG1   CD1   sing N N 240 
ILE CG1   HG12  sing N N 241 
ILE CG1   HG13  sing N N 242 
ILE CG2   HG21  sing N N 243 
ILE CG2   HG22  sing N N 244 
ILE CG2   HG23  sing N N 245 
ILE CD1   HD11  sing N N 246 
ILE CD1   HD12  sing N N 247 
ILE CD1   HD13  sing N N 248 
ILE OXT   HXT   sing N N 249 
JQ9 C22   C21   sing N N 250 
JQ9 C12   C11   sing N N 251 
JQ9 O2    C2    doub N N 252 
JQ9 C21   N3    sing N N 253 
JQ9 C2    N3    sing N N 254 
JQ9 C2    N1    sing N N 255 
JQ9 C11   N1    sing N N 256 
JQ9 N3    C4    sing N N 257 
JQ9 N1    C6    sing N N 258 
JQ9 C4    N9    sing Y N 259 
JQ9 C4    C5    doub Y N 260 
JQ9 C6    C5    sing N N 261 
JQ9 C6    O6    doub N N 262 
JQ9 N9    C8    doub Y N 263 
JQ9 C5    N7    sing Y N 264 
JQ9 C8    N7    sing Y N 265 
JQ9 C8    CA    sing N N 266 
JQ9 N7    C7    sing N N 267 
JQ9 CB    CA    doub N E 268 
JQ9 CB    "C1'" sing N N 269 
JQ9 "C2'" "C1'" doub Y N 270 
JQ9 "C2'" "C3'" sing Y N 271 
JQ9 "C9'" "O3'" sing N N 272 
JQ9 "C1'" "C6'" sing Y N 273 
JQ9 "O3'" "C3'" sing N N 274 
JQ9 "C3'" "C4'" doub Y N 275 
JQ9 "C6'" "C5'" doub Y N 276 
JQ9 "C4'" "C5'" sing Y N 277 
JQ9 "C4'" "O4'" sing N N 278 
JQ9 "O4'" "C8'" sing N N 279 
JQ9 C12   H1    sing N N 280 
JQ9 C12   H2    sing N N 281 
JQ9 C12   H3    sing N N 282 
JQ9 C21   H4    sing N N 283 
JQ9 C21   H5    sing N N 284 
JQ9 C22   H6    sing N N 285 
JQ9 C22   H7    sing N N 286 
JQ9 C22   H8    sing N N 287 
JQ9 C7    H9    sing N N 288 
JQ9 C7    H10   sing N N 289 
JQ9 C7    H11   sing N N 290 
JQ9 C11   H12   sing N N 291 
JQ9 C11   H13   sing N N 292 
JQ9 CA    H14   sing N N 293 
JQ9 CB    H15   sing N N 294 
JQ9 "C6'" H16   sing N N 295 
JQ9 "C5'" H17   sing N N 296 
JQ9 "C8'" H18   sing N N 297 
JQ9 "C8'" H19   sing N N 298 
JQ9 "C8'" H20   sing N N 299 
JQ9 "C2'" H21   sing N N 300 
JQ9 "C9'" H22   sing N N 301 
JQ9 "C9'" H23   sing N N 302 
JQ9 "C9'" H24   sing N N 303 
LEU N     CA    sing N N 304 
LEU N     H     sing N N 305 
LEU N     H2    sing N N 306 
LEU CA    C     sing N N 307 
LEU CA    CB    sing N N 308 
LEU CA    HA    sing N N 309 
LEU C     O     doub N N 310 
LEU C     OXT   sing N N 311 
LEU CB    CG    sing N N 312 
LEU CB    HB2   sing N N 313 
LEU CB    HB3   sing N N 314 
LEU CG    CD1   sing N N 315 
LEU CG    CD2   sing N N 316 
LEU CG    HG    sing N N 317 
LEU CD1   HD11  sing N N 318 
LEU CD1   HD12  sing N N 319 
LEU CD1   HD13  sing N N 320 
LEU CD2   HD21  sing N N 321 
LEU CD2   HD22  sing N N 322 
LEU CD2   HD23  sing N N 323 
LEU OXT   HXT   sing N N 324 
LYS N     CA    sing N N 325 
LYS N     H     sing N N 326 
LYS N     H2    sing N N 327 
LYS CA    C     sing N N 328 
LYS CA    CB    sing N N 329 
LYS CA    HA    sing N N 330 
LYS C     O     doub N N 331 
LYS C     OXT   sing N N 332 
LYS CB    CG    sing N N 333 
LYS CB    HB2   sing N N 334 
LYS CB    HB3   sing N N 335 
LYS CG    CD    sing N N 336 
LYS CG    HG2   sing N N 337 
LYS CG    HG3   sing N N 338 
LYS CD    CE    sing N N 339 
LYS CD    HD2   sing N N 340 
LYS CD    HD3   sing N N 341 
LYS CE    NZ    sing N N 342 
LYS CE    HE2   sing N N 343 
LYS CE    HE3   sing N N 344 
LYS NZ    HZ1   sing N N 345 
LYS NZ    HZ2   sing N N 346 
LYS NZ    HZ3   sing N N 347 
LYS OXT   HXT   sing N N 348 
MET N     CA    sing N N 349 
MET N     H     sing N N 350 
MET N     H2    sing N N 351 
MET CA    C     sing N N 352 
MET CA    CB    sing N N 353 
MET CA    HA    sing N N 354 
MET C     O     doub N N 355 
MET C     OXT   sing N N 356 
MET CB    CG    sing N N 357 
MET CB    HB2   sing N N 358 
MET CB    HB3   sing N N 359 
MET CG    SD    sing N N 360 
MET CG    HG2   sing N N 361 
MET CG    HG3   sing N N 362 
MET SD    CE    sing N N 363 
MET CE    HE1   sing N N 364 
MET CE    HE2   sing N N 365 
MET CE    HE3   sing N N 366 
MET OXT   HXT   sing N N 367 
OLA C1    O1    doub N N 368 
OLA C1    O2    sing N N 369 
OLA C1    C2    sing N N 370 
OLA O2    HO2   sing N N 371 
OLA C2    C3    sing N N 372 
OLA C2    H21   sing N N 373 
OLA C2    H22   sing N N 374 
OLA C3    C4    sing N N 375 
OLA C3    H31   sing N N 376 
OLA C3    H32   sing N N 377 
OLA C4    C5    sing N N 378 
OLA C4    H41   sing N N 379 
OLA C4    H42   sing N N 380 
OLA C5    C6    sing N N 381 
OLA C5    H51   sing N N 382 
OLA C5    H52   sing N N 383 
OLA C6    C7    sing N N 384 
OLA C6    H61   sing N N 385 
OLA C6    H62   sing N N 386 
OLA C7    C8    sing N N 387 
OLA C7    H71   sing N N 388 
OLA C7    H72   sing N N 389 
OLA C8    C9    sing N N 390 
OLA C8    H81   sing N N 391 
OLA C8    H82   sing N N 392 
OLA C9    C10   doub N Z 393 
OLA C9    H9    sing N N 394 
OLA C10   C11   sing N N 395 
OLA C10   H10   sing N N 396 
OLA C11   C12   sing N N 397 
OLA C11   H111  sing N N 398 
OLA C11   H112  sing N N 399 
OLA C12   C13   sing N N 400 
OLA C12   H121  sing N N 401 
OLA C12   H122  sing N N 402 
OLA C13   C14   sing N N 403 
OLA C13   H131  sing N N 404 
OLA C13   H132  sing N N 405 
OLA C14   C15   sing N N 406 
OLA C14   H141  sing N N 407 
OLA C14   H142  sing N N 408 
OLA C15   C16   sing N N 409 
OLA C15   H151  sing N N 410 
OLA C15   H152  sing N N 411 
OLA C16   C17   sing N N 412 
OLA C16   H161  sing N N 413 
OLA C16   H162  sing N N 414 
OLA C17   C18   sing N N 415 
OLA C17   H171  sing N N 416 
OLA C17   H172  sing N N 417 
OLA C18   H181  sing N N 418 
OLA C18   H182  sing N N 419 
OLA C18   H183  sing N N 420 
OLB C1    O19   doub N N 421 
OLB C1    O20   sing N N 422 
OLB C2    C1    sing N N 423 
OLB C3    C2    sing N N 424 
OLB C4    C3    sing N N 425 
OLB C5    C4    sing N N 426 
OLB C5    C6    sing N N 427 
OLB O20   C21   sing N N 428 
OLB C21   C22   sing N N 429 
OLB C22   C24   sing N N 430 
OLB O23   C22   sing N N 431 
OLB C24   O25   sing N N 432 
OLB C6    C7    sing N N 433 
OLB C7    C8    sing N N 434 
OLB C8    C9    sing N N 435 
OLB C9    C10   doub N Z 436 
OLB C10   C11   sing N N 437 
OLB C2    H2    sing N N 438 
OLB C2    H2A   sing N N 439 
OLB C3    H3    sing N N 440 
OLB C3    H3A   sing N N 441 
OLB C4    H4    sing N N 442 
OLB C4    H4A   sing N N 443 
OLB C5    H5    sing N N 444 
OLB C5    H5A   sing N N 445 
OLB C21   H21   sing N N 446 
OLB C21   H21A  sing N N 447 
OLB C22   H22   sing N N 448 
OLB O23   HO23  sing N N 449 
OLB C24   H24   sing N N 450 
OLB C24   H24A  sing N N 451 
OLB O25   HO25  sing N N 452 
OLB C6    H16   sing N N 453 
OLB C6    H17   sing N N 454 
OLB C7    H18   sing N N 455 
OLB C7    H19   sing N N 456 
OLB C8    H20   sing N N 457 
OLB C8    H211  sing N N 458 
OLB C9    H221  sing N N 459 
OLB C10   H23   sing N N 460 
OLB C11   H241  sing N N 461 
OLB C11   H25   sing N N 462 
OLB C11   C12   sing N N 463 
OLB C12   H26   sing N N 464 
OLB C12   C13   sing N N 465 
OLB C12   H27   sing N N 466 
OLB C13   C14   sing N N 467 
OLB C13   H28   sing N N 468 
OLB C13   H29   sing N N 469 
OLB C14   H30   sing N N 470 
OLB C14   H31   sing N N 471 
OLB C14   C15   sing N N 472 
OLB C15   C16   sing N N 473 
OLB C15   H32   sing N N 474 
OLB C15   H33   sing N N 475 
OLB C16   H34   sing N N 476 
OLB C16   H35   sing N N 477 
OLB C16   C17   sing N N 478 
OLB C17   C18   sing N N 479 
OLB C17   H36   sing N N 480 
OLB C17   H37   sing N N 481 
OLB C18   H38   sing N N 482 
OLB C18   H39   sing N N 483 
OLB C18   H40   sing N N 484 
OLC C18   C17   sing N N 485 
OLC C10   C9    doub N N 486 
OLC C10   C11   sing N N 487 
OLC C9    C8    sing N N 488 
OLC C17   C16   sing N Z 489 
OLC C11   C12   sing N N 490 
OLC C8    C7    sing N N 491 
OLC C24   C22   sing N N 492 
OLC C24   O25   sing N N 493 
OLC C16   C15   sing N N 494 
OLC C12   C13   sing N N 495 
OLC C7    C6    sing N N 496 
OLC C15   C14   sing N N 497 
OLC C13   C14   sing N N 498 
OLC C6    C5    sing N N 499 
OLC C5    C4    sing N N 500 
OLC C4    C3    sing N N 501 
OLC C3    C2    sing N N 502 
OLC C2    C1    sing N N 503 
OLC C21   C22   sing N N 504 
OLC C21   O20   sing N N 505 
OLC C1    O19   doub N N 506 
OLC C1    O20   sing N N 507 
OLC C22   O23   sing N N 508 
OLC C18   H18   sing N N 509 
OLC C18   H18A  sing N N 510 
OLC C18   H18B  sing N N 511 
OLC C10   H10   sing N N 512 
OLC C9    H9    sing N N 513 
OLC C17   H17   sing N N 514 
OLC C17   H17A  sing N N 515 
OLC C11   H11   sing N N 516 
OLC C11   H11A  sing N N 517 
OLC C8    H8    sing N N 518 
OLC C8    H8A   sing N N 519 
OLC C24   H24   sing N N 520 
OLC C24   H24A  sing N N 521 
OLC C16   H16   sing N N 522 
OLC C16   H16A  sing N N 523 
OLC C12   H12   sing N N 524 
OLC C12   H12A  sing N N 525 
OLC C7    H7    sing N N 526 
OLC C7    H7A   sing N N 527 
OLC C15   H15   sing N N 528 
OLC C15   H15A  sing N N 529 
OLC C13   H13   sing N N 530 
OLC C13   H13A  sing N N 531 
OLC C6    H6    sing N N 532 
OLC C6    H6A   sing N N 533 
OLC C14   H14   sing N N 534 
OLC C14   H14A  sing N N 535 
OLC C5    H5    sing N N 536 
OLC C5    H5A   sing N N 537 
OLC C4    H4    sing N N 538 
OLC C4    H4A   sing N N 539 
OLC C3    H3    sing N N 540 
OLC C3    H3A   sing N N 541 
OLC C2    H2    sing N N 542 
OLC C2    H2A   sing N N 543 
OLC C21   H21   sing N N 544 
OLC C21   H21A  sing N N 545 
OLC C22   H22   sing N N 546 
OLC O25   HO25  sing N N 547 
OLC O23   HO23  sing N N 548 
PHE N     CA    sing N N 549 
PHE N     H     sing N N 550 
PHE N     H2    sing N N 551 
PHE CA    C     sing N N 552 
PHE CA    CB    sing N N 553 
PHE CA    HA    sing N N 554 
PHE C     O     doub N N 555 
PHE C     OXT   sing N N 556 
PHE CB    CG    sing N N 557 
PHE CB    HB2   sing N N 558 
PHE CB    HB3   sing N N 559 
PHE CG    CD1   doub Y N 560 
PHE CG    CD2   sing Y N 561 
PHE CD1   CE1   sing Y N 562 
PHE CD1   HD1   sing N N 563 
PHE CD2   CE2   doub Y N 564 
PHE CD2   HD2   sing N N 565 
PHE CE1   CZ    doub Y N 566 
PHE CE1   HE1   sing N N 567 
PHE CE2   CZ    sing Y N 568 
PHE CE2   HE2   sing N N 569 
PHE CZ    HZ    sing N N 570 
PHE OXT   HXT   sing N N 571 
PRO N     CA    sing N N 572 
PRO N     CD    sing N N 573 
PRO N     H     sing N N 574 
PRO CA    C     sing N N 575 
PRO CA    CB    sing N N 576 
PRO CA    HA    sing N N 577 
PRO C     O     doub N N 578 
PRO C     OXT   sing N N 579 
PRO CB    CG    sing N N 580 
PRO CB    HB2   sing N N 581 
PRO CB    HB3   sing N N 582 
PRO CG    CD    sing N N 583 
PRO CG    HG2   sing N N 584 
PRO CG    HG3   sing N N 585 
PRO CD    HD2   sing N N 586 
PRO CD    HD3   sing N N 587 
PRO OXT   HXT   sing N N 588 
SER N     CA    sing N N 589 
SER N     H     sing N N 590 
SER N     H2    sing N N 591 
SER CA    C     sing N N 592 
SER CA    CB    sing N N 593 
SER CA    HA    sing N N 594 
SER C     O     doub N N 595 
SER C     OXT   sing N N 596 
SER CB    OG    sing N N 597 
SER CB    HB2   sing N N 598 
SER CB    HB3   sing N N 599 
SER OG    HG    sing N N 600 
SER OXT   HXT   sing N N 601 
THR N     CA    sing N N 602 
THR N     H     sing N N 603 
THR N     H2    sing N N 604 
THR CA    C     sing N N 605 
THR CA    CB    sing N N 606 
THR CA    HA    sing N N 607 
THR C     O     doub N N 608 
THR C     OXT   sing N N 609 
THR CB    OG1   sing N N 610 
THR CB    CG2   sing N N 611 
THR CB    HB    sing N N 612 
THR OG1   HG1   sing N N 613 
THR CG2   HG21  sing N N 614 
THR CG2   HG22  sing N N 615 
THR CG2   HG23  sing N N 616 
THR OXT   HXT   sing N N 617 
TRP N     CA    sing N N 618 
TRP N     H     sing N N 619 
TRP N     H2    sing N N 620 
TRP CA    C     sing N N 621 
TRP CA    CB    sing N N 622 
TRP CA    HA    sing N N 623 
TRP C     O     doub N N 624 
TRP C     OXT   sing N N 625 
TRP CB    CG    sing N N 626 
TRP CB    HB2   sing N N 627 
TRP CB    HB3   sing N N 628 
TRP CG    CD1   doub Y N 629 
TRP CG    CD2   sing Y N 630 
TRP CD1   NE1   sing Y N 631 
TRP CD1   HD1   sing N N 632 
TRP CD2   CE2   doub Y N 633 
TRP CD2   CE3   sing Y N 634 
TRP NE1   CE2   sing Y N 635 
TRP NE1   HE1   sing N N 636 
TRP CE2   CZ2   sing Y N 637 
TRP CE3   CZ3   doub Y N 638 
TRP CE3   HE3   sing N N 639 
TRP CZ2   CH2   doub Y N 640 
TRP CZ2   HZ2   sing N N 641 
TRP CZ3   CH2   sing Y N 642 
TRP CZ3   HZ3   sing N N 643 
TRP CH2   HH2   sing N N 644 
TRP OXT   HXT   sing N N 645 
TYR N     CA    sing N N 646 
TYR N     H     sing N N 647 
TYR N     H2    sing N N 648 
TYR CA    C     sing N N 649 
TYR CA    CB    sing N N 650 
TYR CA    HA    sing N N 651 
TYR C     O     doub N N 652 
TYR C     OXT   sing N N 653 
TYR CB    CG    sing N N 654 
TYR CB    HB2   sing N N 655 
TYR CB    HB3   sing N N 656 
TYR CG    CD1   doub Y N 657 
TYR CG    CD2   sing Y N 658 
TYR CD1   CE1   sing Y N 659 
TYR CD1   HD1   sing N N 660 
TYR CD2   CE2   doub Y N 661 
TYR CD2   HD2   sing N N 662 
TYR CE1   CZ    doub Y N 663 
TYR CE1   HE1   sing N N 664 
TYR CE2   CZ    sing Y N 665 
TYR CE2   HE2   sing N N 666 
TYR CZ    OH    sing N N 667 
TYR OH    HH    sing N N 668 
TYR OXT   HXT   sing N N 669 
VAL N     CA    sing N N 670 
VAL N     H     sing N N 671 
VAL N     H2    sing N N 672 
VAL CA    C     sing N N 673 
VAL CA    CB    sing N N 674 
VAL CA    HA    sing N N 675 
VAL C     O     doub N N 676 
VAL C     OXT   sing N N 677 
VAL CB    CG1   sing N N 678 
VAL CB    CG2   sing N N 679 
VAL CB    HB    sing N N 680 
VAL CG1   HG11  sing N N 681 
VAL CG1   HG12  sing N N 682 
VAL CG1   HG13  sing N N 683 
VAL CG2   HG21  sing N N 684 
VAL CG2   HG22  sing N N 685 
VAL CG2   HG23  sing N N 686 
VAL OXT   HXT   sing N N 687 
# 
_pdbx_audit_support.funding_organization   'Agence Nationale de la Recherche (ANR)' 
_pdbx_audit_support.country                France 
_pdbx_audit_support.grant_number           ANR-20-CE11-0019 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5NM2 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'small foils' 
_pdbx_serial_crystallography_sample_delivery.method        'fixed target' 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9FUP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.024894 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.005574 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007021 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062 1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . ALA A 1 9   ? 22.33627  -21.29404 1.64949  1.000 106.54672 ? 0    ALA A N     1 
ATOM   2    C  CA    . ALA A 1 9   ? 23.51655  -20.80073 0.94931  1.000 101.66437 ? 0    ALA A CA    1 
ATOM   3    C  C     . ALA A 1 9   ? 24.70343  -20.71770 1.90414  1.000 98.76432  ? 0    ALA A C     1 
ATOM   4    O  O     . ALA A 1 9   ? 24.51637  -20.57074 3.11271  1.000 101.07245 ? 0    ALA A O     1 
ATOM   5    C  CB    . ALA A 1 9   ? 23.23366  -19.44136 0.33211  1.000 100.76003 ? 0    ALA A CB    1 
ATOM   6    H  H     . ALA A 1 9   ? 21.59675  -20.95562 1.36986  1.000 127.89928 ? 0    ALA A H     1 
ATOM   7    H  HA    . ALA A 1 9   ? 23.74404  -21.41122 0.23067  1.000 122.04046 ? 0    ALA A HA    1 
ATOM   8    H  HB1   . ALA A 1 9   ? 24.04439  -19.10834 -0.08348 1.000 120.95525 ? 0    ALA A HB1   1 
ATOM   9    H  HB2   . ALA A 1 9   ? 22.53526  -19.53629 -0.33432 1.000 120.95525 ? 0    ALA A HB2   1 
ATOM   10   H  HB3   . ALA A 1 9   ? 22.94494  -18.83189 1.02931  1.000 120.95525 ? 0    ALA A HB3   1 
ATOM   11   N  N     . PRO A 1 10  ? 25.92096  -20.80931 1.37457  1.000 101.95619 ? 1    PRO A N     1 
ATOM   12   C  CA    . PRO A 1 10  ? 27.10583  -20.68578 2.23118  1.000 101.07384 ? 1    PRO A CA    1 
ATOM   13   C  C     . PRO A 1 10  ? 27.06432  -19.38168 3.00444  1.000 101.54504 ? 1    PRO A C     1 
ATOM   14   O  O     . PRO A 1 10  ? 26.94527  -18.30322 2.40376  1.000 105.33921 ? 1    PRO A O     1 
ATOM   15   C  CB    . PRO A 1 10  ? 28.27601  -20.71800 1.23304  1.000 98.33177  ? 1    PRO A CB    1 
ATOM   16   C  CG    . PRO A 1 10  ? 27.67689  -20.35436 -0.08135 1.000 98.78207  ? 1    PRO A CG    1 
ATOM   17   C  CD    . PRO A 1 10  ? 26.28294  -20.90849 -0.05109 1.000 98.61015  ? 1    PRO A CD    1 
ATOM   18   H  HA    . PRO A 1 10  ? 27.18375  -21.43483 2.84253  1.000 121.33183 ? 1    PRO A HA    1 
ATOM   19   H  HB2   . PRO A 1 10  ? 28.95143  -20.07345 1.49623  1.000 118.04134 ? 1    PRO A HB2   1 
ATOM   20   H  HB3   . PRO A 1 10  ? 28.66023  -21.60819 1.20437  1.000 118.04134 ? 1    PRO A HB3   1 
ATOM   21   H  HG2   . PRO A 1 10  ? 27.66272  -19.38958 -0.18077 1.000 118.58170 ? 1    PRO A HG2   1 
ATOM   22   H  HG3   . PRO A 1 10  ? 28.19181  -20.75435 -0.79951 1.000 118.58170 ? 1    PRO A HG3   1 
ATOM   23   H  HD2   . PRO A 1 10  ? 25.68570  -20.37506 -0.59849 1.000 118.37539 ? 1    PRO A HD2   1 
ATOM   24   H  HD3   . PRO A 1 10  ? 26.27012  -21.83159 -0.34877 1.000 118.37539 ? 1    PRO A HD3   1 
ATOM   25   N  N     . PRO A 1 11  ? 27.14674  -19.43320 4.33793  1.000 100.67990 ? 2    PRO A N     1 
ATOM   26   C  CA    . PRO A 1 11  ? 26.94315  -18.20456 5.12501  1.000 100.22599 ? 2    PRO A CA    1 
ATOM   27   C  C     . PRO A 1 11  ? 27.80028  -17.03741 4.67233  1.000 95.71724  ? 2    PRO A C     1 
ATOM   28   O  O     . PRO A 1 11  ? 27.42009  -15.87900 4.88705  1.000 96.07406  ? 2    PRO A O     1 
ATOM   29   C  CB    . PRO A 1 11  ? 27.30255  -18.63947 6.55409  1.000 105.94844 ? 2    PRO A CB    1 
ATOM   30   C  CG    . PRO A 1 11  ? 27.10973  -20.11440 6.56974  1.000 102.00476 ? 2    PRO A CG    1 
ATOM   31   C  CD    . PRO A 1 11  ? 27.45966  -20.59395 5.19305  1.000 93.66441  ? 2    PRO A CD    1 
ATOM   32   H  HA    . PRO A 1 11  ? 26.00815  -17.94887 5.08908  1.000 120.31441 ? 2    PRO A HA    1 
ATOM   33   H  HB2   . PRO A 1 11  ? 28.22456  -18.40814 6.74720  1.000 127.18135 ? 2    PRO A HB2   1 
ATOM   34   H  HB3   . PRO A 1 11  ? 26.71163  -18.20565 7.18932  1.000 127.18135 ? 2    PRO A HB3   1 
ATOM   35   H  HG2   . PRO A 1 11  ? 27.69683  -20.51310 7.23100  1.000 122.44893 ? 2    PRO A HG2   1 
ATOM   36   H  HG3   . PRO A 1 11  ? 26.18537  -20.32029 6.77965  1.000 122.44893 ? 2    PRO A HG3   1 
ATOM   37   H  HD2   . PRO A 1 11  ? 28.40100  -20.82089 5.13569  1.000 112.44050 ? 2    PRO A HD2   1 
ATOM   38   H  HD3   . PRO A 1 11  ? 26.91809  -21.36000 4.94655  1.000 112.44050 ? 2    PRO A HD3   1 
ATOM   39   N  N     . ILE A 1 12  ? 28.94385  -17.30410 4.03841  1.000 97.13377  ? 3    ILE A N     1 
ATOM   40   C  CA    . ILE A 1 12  ? 29.85851  -16.22228 3.69483  1.000 93.27887  ? 3    ILE A CA    1 
ATOM   41   C  C     . ILE A 1 12  ? 29.25086  -15.30016 2.64605  1.000 89.98711  ? 3    ILE A C     1 
ATOM   42   O  O     . ILE A 1 12  ? 29.54198  -14.09863 2.62798  1.000 85.60230  ? 3    ILE A O     1 
ATOM   43   C  CB    . ILE A 1 12  ? 31.20755  -16.79612 3.22367  1.000 96.12193  ? 3    ILE A CB    1 
ATOM   44   C  CG1   . ILE A 1 12  ? 32.20807  -15.66454 2.98126  1.000 94.17849  ? 3    ILE A CG1   1 
ATOM   45   C  CG2   . ILE A 1 12  ? 31.02559  -17.61109 1.95337  1.000 96.77255  ? 3    ILE A CG2   1 
ATOM   46   C  CD1   . ILE A 1 12  ? 33.65373  -16.11591 2.96912  1.000 85.95192  ? 3    ILE A CD1   1 
ATOM   47   H  H     . ILE A 1 12  ? 29.20656  -18.08800 3.80159  1.000 116.60374 ? 3    ILE A H     1 
ATOM   48   H  HA    . ILE A 1 12  ? 30.01488  -15.69441 4.49346  1.000 111.97786 ? 3    ILE A HA    1 
ATOM   49   H  HB    . ILE A 1 12  ? 31.55085  -17.37679 3.92071  1.000 115.38953 ? 3    ILE A HB    1 
ATOM   50   H  HG12  . ILE A 1 12  ? 32.01771  -15.25972 2.12057  1.000 113.05740 ? 3    ILE A HG12  1 
ATOM   51   H  HG13  . ILE A 1 12  ? 32.11010  -15.00592 3.68661  1.000 113.05740 ? 3    ILE A HG13  1 
ATOM   52   H  HG21  . ILE A 1 12  ? 31.88712  -17.95976 1.67573  1.000 116.17027 ? 3    ILE A HG21  1 
ATOM   53   H  HG22  . ILE A 1 12  ? 30.41470  -18.34296 2.13249  1.000 116.17027 ? 3    ILE A HG22  1 
ATOM   54   H  HG23  . ILE A 1 12  ? 30.66153  -17.03846 1.26022  1.000 116.17027 ? 3    ILE A HG23  1 
ATOM   55   H  HD11  . ILE A 1 12  ? 34.22332  -15.34698 2.81033  1.000 103.18551 ? 3    ILE A HD11  1 
ATOM   56   H  HD12  . ILE A 1 12  ? 33.86741  -16.51423 3.82737  1.000 103.18551 ? 3    ILE A HD12  1 
ATOM   57   H  HD13  . ILE A 1 12  ? 33.77478  -16.76886 2.26209  1.000 103.18551 ? 3    ILE A HD13  1 
ATOM   58   N  N     . MET A 1 13  ? 28.40291  -15.82818 1.76198  1.000 92.48129  ? 4    MET A N     1 
ATOM   59   C  CA    . MET A 1 13  ? 27.84276  -15.00214 0.69585  1.000 88.07510  ? 4    MET A CA    1 
ATOM   60   C  C     . MET A 1 13  ? 26.92512  -13.92708 1.26420  1.000 83.88688  ? 4    MET A C     1 
ATOM   61   O  O     . MET A 1 13  ? 27.13797  -12.72882 1.04243  1.000 81.06103  ? 4    MET A O     1 
ATOM   62   C  CB    . MET A 1 13  ? 27.09766  -15.87969 -0.31134 1.000 87.06776  ? 4    MET A CB    1 
ATOM   63   C  CG    . MET A 1 13  ? 28.00770  -16.51151 -1.35265 1.000 88.34904  ? 4    MET A CG    1 
ATOM   64   S  SD    . MET A 1 13  ? 27.20634  -17.78539 -2.34951 1.000 95.17238  ? 4    MET A SD    1 
ATOM   65   C  CE    . MET A 1 13  ? 26.21529  -16.80065 -3.46971 1.000 75.43719  ? 4    MET A CE    1 
ATOM   66   H  H     . MET A 1 13  ? 28.14112  -16.64735 1.75831  1.000 111.02076 ? 4    MET A H     1 
ATOM   67   H  HA    . MET A 1 13  ? 28.57233  -14.57008 0.22472  1.000 105.73333 ? 4    MET A HA    1 
ATOM   68   H  HB2   . MET A 1 13  ? 26.65127  -16.59562 0.16729  1.000 104.52452 ? 4    MET A HB2   1 
ATOM   69   H  HB3   . MET A 1 13  ? 26.44464  -15.33509 -0.77812 1.000 104.52452 ? 4    MET A HB3   1 
ATOM   70   H  HG2   . MET A 1 13  ? 28.31987  -15.81842 -1.95521 1.000 106.06206 ? 4    MET A HG2   1 
ATOM   71   H  HG3   . MET A 1 13  ? 28.76120  -16.92174 -0.90006 1.000 106.06206 ? 4    MET A HG3   1 
ATOM   72   H  HE1   . MET A 1 13  ? 25.75248  -17.39134 -4.08436 1.000 90.56785  ? 4    MET A HE1   1 
ATOM   73   H  HE2   . MET A 1 13  ? 25.57182  -16.28867 -2.95520 1.000 90.56785  ? 4    MET A HE2   1 
ATOM   74   H  HE3   . MET A 1 13  ? 26.79725  -16.20094 -3.96223 1.000 90.56785  ? 4    MET A HE3   1 
ATOM   75   N  N     . GLY A 1 14  ? 25.88915  -14.33758 1.99633  1.000 84.42651  ? 5    GLY A N     1 
ATOM   76   C  CA    . GLY A 1 14  ? 25.05414  -13.36095 2.67285  1.000 88.91377  ? 5    GLY A CA    1 
ATOM   77   C  C     . GLY A 1 14  ? 25.85524  -12.47274 3.60362  1.000 83.40482  ? 5    GLY A C     1 
ATOM   78   O  O     . GLY A 1 14  ? 25.61790  -11.26482 3.68446  1.000 79.84259  ? 5    GLY A O     1 
ATOM   79   H  H     . GLY A 1 14  ? 25.65690  -15.15745 2.11236  1.000 101.35503 ? 5    GLY A H     1 
ATOM   80   H  HA2   . GLY A 1 14  ? 24.61670  -12.79952 2.01380  1.000 106.73974 ? 5    GLY A HA2   1 
ATOM   81   H  HA3   . GLY A 1 14  ? 24.37803  -13.82129 3.19426  1.000 106.73974 ? 5    GLY A HA3   1 
ATOM   82   N  N     . SER A 1 15  ? 26.81390  -13.05979 4.32362  1.000 81.74352  ? 6    SER A N     1 
ATOM   83   C  CA    . SER A 1 15  ? 27.68543  -12.25775 5.17377  1.000 80.92547  ? 6    SER A CA    1 
ATOM   84   C  C     . SER A 1 15  ? 28.40783  -11.19105 4.35953  1.000 76.83975  ? 6    SER A C     1 
ATOM   85   O  O     . SER A 1 15  ? 28.51518  -10.03800 4.79197  1.000 72.97051  ? 6    SER A O     1 
ATOM   86   C  CB    . SER A 1 15  ? 28.68328  -13.16058 5.90015  1.000 82.81802  ? 6    SER A CB    1 
ATOM   87   O  OG    . SER A 1 15  ? 28.02424  -13.96796 6.86247  1.000 89.29886  ? 6    SER A OG    1 
ATOM   88   H  H     . SER A 1 15  ? 26.97560  -13.90436 4.33590  1.000 98.13544  ? 6    SER A H     1 
ATOM   89   H  HA    . SER A 1 15  ? 27.14974  -11.80914 5.84659  1.000 97.15378  ? 6    SER A HA    1 
ATOM   90   H  HB2   . SER A 1 15  ? 29.11992  -13.73482 5.25170  1.000 99.42484  ? 6    SER A HB2   1 
ATOM   91   H  HB3   . SER A 1 15  ? 29.34119  -12.60715 6.34934  1.000 99.42484  ? 6    SER A HB3   1 
ATOM   92   H  HG    . SER A 1 15  ? 28.58921  -14.34323 7.35805  1.000 107.20184 ? 6    SER A HG    1 
ATOM   93   N  N     . SER A 1 16  ? 28.88591  -11.54944 3.16394  1.000 77.30808  ? 7    SER A N     1 
ATOM   94   C  CA    . SER A 1 16  ? 29.61009  -10.58749 2.33830  1.000 71.95359  ? 7    SER A CA    1 
ATOM   95   C  C     . SER A 1 16  ? 28.74711  -9.37226  2.02132  1.000 67.20715  ? 7    SER A C     1 
ATOM   96   O  O     . SER A 1 16  ? 29.23095  -8.23387  2.04513  1.000 58.15128  ? 7    SER A O     1 
ATOM   97   C  CB    . SER A 1 16  ? 30.08074  -11.25272 1.04444  1.000 73.35016  ? 7    SER A CB    1 
ATOM   98   O  OG    . SER A 1 16  ? 30.71707  -12.49084 1.30403  1.000 85.36633  ? 7    SER A OG    1 
ATOM   99   H  H     . SER A 1 16  ? 28.80471  -12.33133 2.81513  1.000 92.81291  ? 7    SER A H     1 
ATOM   100  H  HA    . SER A 1 16  ? 30.39211  -10.28699 2.82723  1.000 86.38752  ? 7    SER A HA    1 
ATOM   101  H  HB2   . SER A 1 16  ? 29.31186  -11.40853 0.47396  1.000 88.06340  ? 7    SER A HB2   1 
ATOM   102  H  HB3   . SER A 1 16  ? 30.70999  -10.66363 0.59955  1.000 88.06340  ? 7    SER A HB3   1 
ATOM   103  H  HG    . SER A 1 16  ? 30.14292  -13.07634 1.48609  1.000 102.48281 ? 7    SER A HG    1 
ATOM   104  N  N     . VAL A 1 17  ? 27.46645  -9.59330  1.71701  1.000 66.84885  ? 8    VAL A N     1 
ATOM   105  C  CA    . VAL A 1 17  ? 26.57245  -8.47995  1.41316  1.000 68.80150  ? 8    VAL A CA    1 
ATOM   106  C  C     . VAL A 1 17  ? 26.35703  -7.61958  2.65238  1.000 66.67094  ? 8    VAL A C     1 
ATOM   107  O  O     . VAL A 1 17  ? 26.40082  -6.38461  2.59004  1.000 61.55892  ? 8    VAL A O     1 
ATOM   108  C  CB    . VAL A 1 17  ? 25.23428  -9.00134  0.85787  1.000 68.58009  ? 8    VAL A CB    1 
ATOM   109  C  CG1   . VAL A 1 17  ? 24.27157  -7.84608  0.61644  1.000 69.21020  ? 8    VAL A CG1   1 
ATOM   110  C  CG2   . VAL A 1 17  ? 25.45789  -9.78979  -0.41901 1.000 68.50681  ? 8    VAL A CG2   1 
ATOM   111  H  H     . VAL A 1 17  ? 27.09665  -10.36887 1.68046  1.000 80.26183  ? 8    VAL A H     1 
ATOM   112  H  HA    . VAL A 1 17  ? 26.98918  -7.93012  0.73131  1.000 82.60502  ? 8    VAL A HA    1 
ATOM   113  H  HB    . VAL A 1 17  ? 24.83394  -9.59606  1.51127  1.000 82.33932  ? 8    VAL A HB    1 
ATOM   114  H  HG11  . VAL A 1 17  ? 23.51904  -8.16590  0.09461  1.000 83.09545  ? 8    VAL A HG11  1 
ATOM   115  H  HG12  . VAL A 1 17  ? 23.96172  -7.50921  1.47167  1.000 83.09545  ? 8    VAL A HG12  1 
ATOM   116  H  HG13  . VAL A 1 17  ? 24.73511  -7.14451  0.13287  1.000 83.09545  ? 8    VAL A HG13  1 
ATOM   117  H  HG21  . VAL A 1 17  ? 24.59895  -10.07201 -0.77041 1.000 82.25139  ? 8    VAL A HG21  1 
ATOM   118  H  HG22  . VAL A 1 17  ? 25.90962  -9.22398  -1.06453 1.000 82.25139  ? 8    VAL A HG22  1 
ATOM   119  H  HG23  . VAL A 1 17  ? 26.00471  -10.56570 -0.21939 1.000 82.25139  ? 8    VAL A HG23  1 
ATOM   120  N  N     . TYR A 1 18  ? 26.10404  -8.26010  3.79538  1.000 70.84094  ? 9    TYR A N     1 
ATOM   121  C  CA    . TYR A 1 18  ? 25.90902  -7.51192  5.03275  1.000 65.25650  ? 9    TYR A CA    1 
ATOM   122  C  C     . TYR A 1 18  ? 27.17105  -6.74630  5.41557  1.000 58.09208  ? 9    TYR A C     1 
ATOM   123  O  O     . TYR A 1 18  ? 27.10304  -5.56485  5.77444  1.000 57.01894  ? 9    TYR A O     1 
ATOM   124  C  CB    . TYR A 1 18  ? 25.47524  -8.46452  6.15249  1.000 65.52665  ? 9    TYR A CB    1 
ATOM   125  C  CG    . TYR A 1 18  ? 25.54719  -7.86915  7.54328  1.000 60.05945  ? 9    TYR A CG    1 
ATOM   126  C  CD1   . TYR A 1 18  ? 24.68892  -6.84973  7.93612  1.000 58.18519  ? 9    TYR A CD1   1 
ATOM   127  C  CD2   . TYR A 1 18  ? 26.47004  -8.33550  8.46632  1.000 59.49993  ? 9    TYR A CD2   1 
ATOM   128  C  CE1   . TYR A 1 18  ? 24.76171  -6.30685  9.20718  1.000 55.71159  ? 9    TYR A CE1   1 
ATOM   129  C  CE2   . TYR A 1 18  ? 26.55406  -7.79746  9.73299  1.000 59.05614  ? 9    TYR A CE2   1 
ATOM   130  C  CZ    . TYR A 1 18  ? 25.69627  -6.78710  10.10095 1.000 58.34663  ? 9    TYR A CZ    1 
ATOM   131  O  OH    . TYR A 1 18  ? 25.77829  -6.25651  11.36767 1.000 53.79617  ? 9    TYR A OH    1 
ATOM   132  H  H     . TYR A 1 18  ? 26.04147  -9.11377  3.87866  1.000 85.05235  ? 9    TYR A H     1 
ATOM   133  H  HA    . TYR A 1 18  ? 25.19958  -6.86247  4.90698  1.000 78.35102  ? 9    TYR A HA    1 
ATOM   134  H  HB2   . TYR A 1 18  ? 24.55574  -8.72973  5.99413  1.000 78.67519  ? 9    TYR A HB2   1 
ATOM   135  H  HB3   . TYR A 1 18  ? 26.05269  -9.24376  6.13674  1.000 78.67519  ? 9    TYR A HB3   1 
ATOM   136  H  HD1   . TYR A 1 18  ? 24.05592  -6.52723  7.33595  1.000 69.86544  ? 9    TYR A HD1   1 
ATOM   137  H  HD2   . TYR A 1 18  ? 27.04482  -9.02603  8.22614  1.000 71.44314  ? 9    TYR A HD2   1 
ATOM   138  H  HE1   . TYR A 1 18  ? 24.18395  -5.62232  9.45722  1.000 66.89712  ? 9    TYR A HE1   1 
ATOM   139  H  HE2   . TYR A 1 18  ? 27.18716  -8.11588  10.33524 1.000 70.91058  ? 9    TYR A HE2   1 
ATOM   140  H  HH    . TYR A 1 18  ? 25.24602  -5.61115  11.44385 1.000 64.59862  ? 9    TYR A HH    1 
ATOM   141  N  N     . ILE A 1 19  ? 28.33560  -7.39345  5.32791  1.000 59.72471  ? 10   ILE A N     1 
ATOM   142  C  CA    . ILE A 1 19  ? 29.58099  -6.72218  5.69130  1.000 58.71866  ? 10   ILE A CA    1 
ATOM   143  C  C     . ILE A 1 19  ? 29.84726  -5.54983  4.75215  1.000 57.70018  ? 10   ILE A C     1 
ATOM   144  O  O     . ILE A 1 19  ? 30.23837  -4.46153  5.19061  1.000 50.69322  ? 10   ILE A O     1 
ATOM   145  C  CB    . ILE A 1 19  ? 30.75186  -7.72460  5.69387  1.000 62.60757  ? 10   ILE A CB    1 
ATOM   146  C  CG1   . ILE A 1 19  ? 30.53448  -8.84401  6.72217  1.000 61.36793  ? 10   ILE A CG1   1 
ATOM   147  C  CG2   . ILE A 1 19  ? 32.07230  -7.01183  5.97317  1.000 54.71170  ? 10   ILE A CG2   1 
ATOM   148  C  CD1   . ILE A 1 19  ? 29.72321  -8.44676  7.92621  1.000 66.50573  ? 10   ILE A CD1   1 
ATOM   149  H  H     . ILE A 1 19  ? 28.42900  -8.20709  5.06546  1.000 71.71287  ? 10   ILE A H     1 
ATOM   150  H  HA    . ILE A 1 19  ? 29.48850  -6.37035  6.59050  1.000 70.50560  ? 10   ILE A HA    1 
ATOM   151  H  HB    . ILE A 1 19  ? 30.78628  -8.12606  4.81151  1.000 75.17230  ? 10   ILE A HB    1 
ATOM   152  H  HG12  . ILE A 1 19  ? 30.07059  -9.57617  6.28669  1.000 73.68473  ? 10   ILE A HG12  1 
ATOM   153  H  HG13  . ILE A 1 19  ? 31.40095  -9.14251  7.04000  1.000 73.68473  ? 10   ILE A HG13  1 
ATOM   154  H  HG21  . ILE A 1 19  ? 32.77734  -7.67317  6.05348  1.000 65.69725  ? 10   ILE A HG21  1 
ATOM   155  H  HG22  . ILE A 1 19  ? 32.26688  -6.40839  5.23907  1.000 65.69725  ? 10   ILE A HG22  1 
ATOM   156  H  HG23  . ILE A 1 19  ? 31.99230  -6.51150  6.80031  1.000 65.69725  ? 10   ILE A HG23  1 
ATOM   157  H  HD11  . ILE A 1 19  ? 29.66452  -9.20290  8.53094  1.000 79.85010  ? 10   ILE A HD11  1 
ATOM   158  H  HD12  . ILE A 1 19  ? 30.15927  -7.70205  8.36912  1.000 79.85010  ? 10   ILE A HD12  1 
ATOM   159  H  HD13  . ILE A 1 19  ? 28.83521  -8.18528  7.63641  1.000 79.85010  ? 10   ILE A HD13  1 
ATOM   160  N  N     . THR A 1 20  ? 29.63618  -5.75161  3.44706  1.000 57.00827  ? 11   THR A N     1 
ATOM   161  C  CA    . THR A 1 20  ? 29.91209  -4.69547  2.47641  1.000 53.43489  ? 11   THR A CA    1 
ATOM   162  C  C     . THR A 1 20  ? 29.05212  -3.46608  2.74532  1.000 53.04616  ? 11   THR A C     1 
ATOM   163  O  O     . THR A 1 20  ? 29.54325  -2.32977  2.70974  1.000 48.53105  ? 11   THR A O     1 
ATOM   164  C  CB    . THR A 1 20  ? 29.67130  -5.22076  1.05766  1.000 54.55504  ? 11   THR A CB    1 
ATOM   165  O  OG1   . THR A 1 20  ? 30.50434  -6.36205  0.81685  1.000 60.65355  ? 11   THR A OG1   1 
ATOM   166  C  CG2   . THR A 1 20  ? 29.98600  -4.15367  0.02318  1.000 57.14288  ? 11   THR A CG2   1 
ATOM   167  H  H     . THR A 1 20  ? 29.33772  -6.48175  3.10440  1.000 68.45314  ? 11   THR A H     1 
ATOM   168  H  HA    . THR A 1 20  ? 30.84302  -4.43268  2.54858  1.000 64.16508  ? 11   THR A HA    1 
ATOM   169  H  HB    . THR A 1 20  ? 28.73825  -5.47007  0.96735  1.000 65.50926  ? 11   THR A HB    1 
ATOM   170  H  HG1   . THR A 1 20  ? 30.34452  -6.95947  1.38531  1.000 72.82748  ? 11   THR A HG1   1 
ATOM   171  H  HG21  . THR A 1 20  ? 29.95599  -4.53618  -0.86771 1.000 68.61467  ? 11   THR A HG21  1 
ATOM   172  H  HG22  . THR A 1 20  ? 29.33657  -3.43535  0.07939  1.000 68.61467  ? 11   THR A HG22  1 
ATOM   173  H  HG23  . THR A 1 20  ? 30.87160  -3.79039  0.18012  1.000 68.61467  ? 11   THR A HG23  1 
ATOM   174  N  N     . VAL A 1 21  ? 27.76486  -3.67423  3.01500  1.000 52.57143  ? 12   VAL A N     1 
ATOM   175  C  CA    . VAL A 1 21  ? 26.87532  -2.55730  3.31407  1.000 48.19568  ? 12   VAL A CA    1 
ATOM   176  C  C     . VAL A 1 21  ? 27.29400  -1.87414  4.60888  1.000 55.13165  ? 12   VAL A C     1 
ATOM   177  O  O     . VAL A 1 21  ? 27.29227  -0.64048  4.70630  1.000 56.35385  ? 12   VAL A O     1 
ATOM   178  C  CB    . VAL A 1 21  ? 25.41845  -3.05150  3.37836  1.000 57.59149  ? 12   VAL A CB    1 
ATOM   179  C  CG1   . VAL A 1 21  ? 24.50222  -1.96960  3.92063  1.000 60.57886  ? 12   VAL A CG1   1 
ATOM   180  C  CG2   . VAL A 1 21  ? 24.95847  -3.51070  2.00075  1.000 71.17136  ? 12   VAL A CG2   1 
ATOM   181  H  H     . VAL A 1 21  ? 27.38520  -4.44573  3.03106  1.000 63.12893  ? 12   VAL A H     1 
ATOM   182  H  HA    . VAL A 1 21  ? 26.94373  -1.90389  2.60043  1.000 57.87803  ? 12   VAL A HA    1 
ATOM   183  H  HB    . VAL A 1 21  ? 25.37004  -3.80719  3.98457  1.000 69.15301  ? 12   VAL A HB    1 
ATOM   184  H  HG11  . VAL A 1 21  ? 23.58078  -2.25294  3.81305  1.000 72.73784  ? 12   VAL A HG11  1 
ATOM   185  H  HG12  . VAL A 1 21  ? 24.69826  -1.83162  4.86054  1.000 72.73784  ? 12   VAL A HG12  1 
ATOM   186  H  HG13  . VAL A 1 21  ? 24.65575  -1.14897  3.42677  1.000 72.73784  ? 12   VAL A HG13  1 
ATOM   187  H  HG21  . VAL A 1 21  ? 24.04508  -3.83116  2.06336  1.000 85.44884  ? 12   VAL A HG21  1 
ATOM   188  H  HG22  . VAL A 1 21  ? 25.00478  -2.76150  1.38637  1.000 85.44884  ? 12   VAL A HG22  1 
ATOM   189  H  HG23  . VAL A 1 21  ? 25.53947  -4.22504  1.69569  1.000 85.44884  ? 12   VAL A HG23  1 
ATOM   190  N  N     . GLU A 1 22  ? 27.64969  -2.66074  5.62616  1.000 52.04282  ? 13   GLU A N     1 
ATOM   191  C  CA    . GLU A 1 22  ? 28.07924  -2.08072  6.89419  1.000 52.74820  ? 13   GLU A CA    1 
ATOM   192  C  C     . GLU A 1 22  ? 29.30003  -1.18953  6.70310  1.000 47.66610  ? 13   GLU A C     1 
ATOM   193  O  O     . GLU A 1 22  ? 29.34690  -0.06309  7.20923  1.000 56.31640  ? 13   GLU A O     1 
ATOM   194  C  CB    . GLU A 1 22  ? 28.38099  -3.19079  7.90062  1.000 58.31350  ? 13   GLU A CB    1 
ATOM   195  C  CG    . GLU A 1 22  ? 27.15378  -3.90335  8.44451  1.000 55.79385  ? 13   GLU A CG    1 
ATOM   196  C  CD    . GLU A 1 22  ? 26.42466  -3.08377  9.49194  1.000 51.27187  ? 13   GLU A CD    1 
ATOM   197  O  OE1   . GLU A 1 22  ? 26.25745  -1.86356  9.28625  1.000 51.28677  ? 13   GLU A OE1   1 
ATOM   198  O  OE2   . GLU A 1 22  ? 26.02966  -3.65650  10.52958 1.000 48.89651  ? 13   GLU A OE2   1 
ATOM   199  H  H     . GLU A 1 22  ? 27.65066  -3.52052  5.60678  1.000 62.49461  ? 13   GLU A H     1 
ATOM   200  H  HA    . GLU A 1 22  ? 27.35852  -1.53664  7.24836  1.000 63.34106  ? 13   GLU A HA    1 
ATOM   201  H  HB2   . GLU A 1 22  ? 28.93782  -3.85664  7.46762  1.000 70.01941  ? 13   GLU A HB2   1 
ATOM   202  H  HB3   . GLU A 1 22  ? 28.85248  -2.80358  8.65472  1.000 70.01941  ? 13   GLU A HB3   1 
ATOM   203  H  HG2   . GLU A 1 22  ? 26.53813  -4.07637  7.71517  1.000 66.99583  ? 13   GLU A HG2   1 
ATOM   204  H  HG3   . GLU A 1 22  ? 27.42745  -4.73946  8.85307  1.000 66.99583  ? 13   GLU A HG3   1 
ATOM   205  N  N     . LEU A 1 23  ? 30.30455  -1.67977  5.97460  1.000 51.22000  ? 14   LEU A N     1 
ATOM   206  C  CA    . LEU A 1 23  ? 31.51857  -0.89377  5.78149  1.000 52.80512  ? 14   LEU A CA    1 
ATOM   207  C  C     . LEU A 1 23  ? 31.23172  0.37895   4.99457  1.000 51.63304  ? 14   LEU A C     1 
ATOM   208  O  O     . LEU A 1 23  ? 31.79588  1.43785   5.28802  1.000 47.25709  ? 14   LEU A O     1 
ATOM   209  C  CB    . LEU A 1 23  ? 32.58284  -1.73786  5.08194  1.000 55.99788  ? 14   LEU A CB    1 
ATOM   210  C  CG    . LEU A 1 23  ? 33.09997  -2.93238  5.88988  1.000 53.98849  ? 14   LEU A CG    1 
ATOM   211  C  CD1   . LEU A 1 23  ? 33.99307  -3.81238  5.02848  1.000 66.62609  ? 14   LEU A CD1   1 
ATOM   212  C  CD2   . LEU A 1 23  ? 33.84911  -2.47792  7.13592  1.000 62.45298  ? 14   LEU A CD2   1 
ATOM   213  H  H     . LEU A 1 23  ? 30.30700  -2.44893  5.58991  1.000 61.50722  ? 14   LEU A H     1 
ATOM   214  H  HA    . LEU A 1 23  ? 31.86724  -0.63469  6.64879  1.000 63.40937  ? 14   LEU A HA    1 
ATOM   215  H  HB2   . LEU A 1 23  ? 32.20544  -2.08495  4.25853  1.000 67.24067  ? 14   LEU A HB2   1 
ATOM   216  H  HB3   . LEU A 1 23  ? 33.34330  -1.16901  4.88443  1.000 67.24067  ? 14   LEU A HB3   1 
ATOM   217  H  HG    . LEU A 1 23  ? 32.33740  -3.45684  6.18027  1.000 64.82940  ? 14   LEU A HG    1 
ATOM   218  H  HD11  . LEU A 1 23  ? 34.31483  -4.55504  5.56309  1.000 79.99452  ? 14   LEU A HD11  1 
ATOM   219  H  HD12  . LEU A 1 23  ? 33.47826  -4.14469  4.27652  1.000 79.99452  ? 14   LEU A HD12  1 
ATOM   220  H  HD13  . LEU A 1 23  ? 34.74234  -3.28546  4.70934  1.000 79.99452  ? 14   LEU A HD13  1 
ATOM   221  H  HD21  . LEU A 1 23  ? 34.20928  -3.25615  7.58929  1.000 74.98679  ? 14   LEU A HD21  1 
ATOM   222  H  HD22  . LEU A 1 23  ? 34.57044  -1.88543  6.87222  1.000 74.98679  ? 14   LEU A HD22  1 
ATOM   223  H  HD23  . LEU A 1 23  ? 33.23355  -2.00953  7.72124  1.000 74.98679  ? 14   LEU A HD23  1 
ATOM   224  N  N     . ALA A 1 24  ? 30.35187  0.29895   3.99342  1.000 56.83151  ? 15   ALA A N     1 
ATOM   225  C  CA    . ALA A 1 24  ? 29.97899  1.49909   3.25080  1.000 55.50047  ? 15   ALA A CA    1 
ATOM   226  C  C     . ALA A 1 24  ? 29.33749  2.52868   4.17126  1.000 53.07124  ? 15   ALA A C     1 
ATOM   227  O  O     . ALA A 1 24  ? 29.65899  3.72219   4.10490  1.000 56.01443  ? 15   ALA A O     1 
ATOM   228  C  CB    . ALA A 1 24  ? 29.02982  1.13363   2.10885  1.000 56.35357  ? 15   ALA A CB    1 
ATOM   229  H  H     . ALA A 1 24  ? 29.96551  -0.42318  3.73102  1.000 68.24103  ? 15   ALA A H     1 
ATOM   230  H  HA    . ALA A 1 24  ? 30.77608  1.89282   2.86280  1.000 66.64378  ? 15   ALA A HA    1 
ATOM   231  H  HB1   . ALA A 1 24  ? 28.80012  1.93883   1.61917  1.000 67.66750  ? 15   ALA A HB1   1 
ATOM   232  H  HB2   . ALA A 1 24  ? 29.47273  0.50314   1.51958  1.000 67.66750  ? 15   ALA A HB2   1 
ATOM   233  H  HB3   . ALA A 1 24  ? 28.22857  0.73249   2.48031  1.000 67.66750  ? 15   ALA A HB3   1 
ATOM   234  N  N     . ILE A 1 25  ? 28.42714  2.08453   5.03865  1.000 52.34113  ? 16   ILE A N     1 
ATOM   235  C  CA    . ILE A 1 25  ? 27.79648  2.99674   5.98851  1.000 56.34446  ? 16   ILE A CA    1 
ATOM   236  C  C     . ILE A 1 25  ? 28.84462  3.60852   6.90717  1.000 51.47850  ? 16   ILE A C     1 
ATOM   237  O  O     . ILE A 1 25  ? 28.79032  4.80202   7.22868  1.000 47.95381  ? 16   ILE A O     1 
ATOM   238  C  CB    . ILE A 1 25  ? 26.69625  2.26224   6.78208  1.000 55.09624  ? 16   ILE A CB    1 
ATOM   239  C  CG1   . ILE A 1 25  ? 25.53675  1.91104   5.84165  1.000 60.88284  ? 16   ILE A CG1   1 
ATOM   240  C  CG2   . ILE A 1 25  ? 26.22055  3.10407   7.96741  1.000 50.00255  ? 16   ILE A CG2   1 
ATOM   241  C  CD1   . ILE A 1 25  ? 24.35994  1.23299   6.50899  1.000 57.83101  ? 16   ILE A CD1   1 
ATOM   242  H  H     . ILE A 1 25  ? 28.16052  1.26896   5.09660  1.000 62.85257  ? 16   ILE A H     1 
ATOM   243  H  HA    . ILE A 1 25  ? 27.37547  3.71857   5.49595  1.000 67.65657  ? 16   ILE A HA    1 
ATOM   244  H  HB    . ILE A 1 25  ? 27.06328  1.44035   7.14360  1.000 66.15871  ? 16   ILE A HB    1 
ATOM   245  H  HG12  . ILE A 1 25  ? 25.21016  2.72979   5.43681  1.000 73.10263  ? 16   ILE A HG12  1 
ATOM   246  H  HG13  . ILE A 1 25  ? 25.86814  1.31087   5.15544  1.000 73.10263  ? 16   ILE A HG13  1 
ATOM   247  H  HG21  . ILE A 1 25  ? 25.52694  2.61892   8.44115  1.000 60.04627  ? 16   ILE A HG21  1 
ATOM   248  H  HG22  . ILE A 1 25  ? 26.97140  3.26946   8.55883  1.000 60.04627  ? 16   ILE A HG22  1 
ATOM   249  H  HG23  . ILE A 1 25  ? 25.86870  3.94520   7.63637  1.000 60.04627  ? 16   ILE A HG23  1 
ATOM   250  H  HD11  . ILE A 1 25  ? 23.69348  1.02280   5.83627  1.000 69.44042  ? 16   ILE A HD11  1 
ATOM   251  H  HD12  . ILE A 1 25  ? 24.66610  0.41825   6.93719  1.000 69.44042  ? 16   ILE A HD12  1 
ATOM   252  H  HD13  . ILE A 1 25  ? 23.98348  1.83343   7.17130  1.000 69.44042  ? 16   ILE A HD13  1 
ATOM   253  N  N     . ALA A 1 26  ? 29.81706  2.80440   7.34036  1.000 49.65731  ? 17   ALA A N     1 
ATOM   254  C  CA    . ALA A 1 26  ? 30.85901  3.31383   8.22499  1.000 50.84592  ? 17   ALA A CA    1 
ATOM   255  C  C     . ALA A 1 26  ? 31.64604  4.43374   7.55398  1.000 51.98933  ? 17   ALA A C     1 
ATOM   256  O  O     . ALA A 1 26  ? 31.90136  5.48028   8.16207  1.000 57.22796  ? 17   ALA A O     1 
ATOM   257  C  CB    . ALA A 1 26  ? 31.78398  2.17156   8.64632  1.000 50.76536  ? 17   ALA A CB    1 
ATOM   258  H  H     . ALA A 1 26  ? 29.89385  1.97190   7.13873  1.000 59.63199  ? 17   ALA A H     1 
ATOM   259  H  HA    . ALA A 1 26  ? 30.44737  3.67733   9.02456  1.000 61.05832  ? 17   ALA A HA    1 
ATOM   260  H  HB1   . ALA A 1 26  ? 32.48142  2.52528   9.22022  1.000 60.96164  ? 17   ALA A HB1   1 
ATOM   261  H  HB2   . ALA A 1 26  ? 31.26611  1.50658   9.12645  1.000 60.96164  ? 17   ALA A HB2   1 
ATOM   262  H  HB3   . ALA A 1 26  ? 32.17754  1.77504   7.85336  1.000 60.96164  ? 17   ALA A HB3   1 
ATOM   263  N  N     . VAL A 1 27  ? 32.03186  4.23328   6.29124  1.000 51.26418  ? 18   VAL A N     1 
ATOM   264  C  CA    . VAL A 1 27  ? 32.76794  5.26196   5.56048  1.000 51.55091  ? 18   VAL A CA    1 
ATOM   265  C  C     . VAL A 1 27  ? 31.96868  6.55881   5.52707  1.000 54.57678  ? 18   VAL A C     1 
ATOM   266  O  O     . VAL A 1 27  ? 32.48181  7.63787   5.84989  1.000 52.90859  ? 18   VAL A O     1 
ATOM   267  C  CB    . VAL A 1 27  ? 33.10242  4.77217   4.13918  1.000 58.13540  ? 18   VAL A CB    1 
ATOM   268  C  CG1   . VAL A 1 27  ? 33.71465  5.89180   3.31367  1.000 62.51456  ? 18   VAL A CG1   1 
ATOM   269  C  CG2   . VAL A 1 27  ? 34.04550  3.58061   4.19211  1.000 59.61638  ? 18   VAL A CG2   1 
ATOM   270  H  H     . VAL A 1 27  ? 31.88071  3.51675   5.84031  1.000 61.56024  ? 18   VAL A H     1 
ATOM   271  H  HA    . VAL A 1 27  ? 33.60207  5.43432   6.02462  1.000 61.90431  ? 18   VAL A HA    1 
ATOM   272  H  HB    . VAL A 1 27  ? 32.27940  4.49261   3.70861  1.000 69.80570  ? 18   VAL A HB    1 
ATOM   273  H  HG11  . VAL A 1 27  ? 34.09415  5.51596   2.50397  1.000 75.06069  ? 18   VAL A HG11  1 
ATOM   274  H  HG12  . VAL A 1 27  ? 33.02235  6.53265   3.08800  1.000 75.06069  ? 18   VAL A HG12  1 
ATOM   275  H  HG13  . VAL A 1 27  ? 34.40910  6.32472   3.83446  1.000 75.06069  ? 18   VAL A HG13  1 
ATOM   276  H  HG21  . VAL A 1 27  ? 34.21815  3.27410   3.28815  1.000 71.58287  ? 18   VAL A HG21  1 
ATOM   277  H  HG22  . VAL A 1 27  ? 34.87571  3.85340   4.61312  1.000 71.58287  ? 18   VAL A HG22  1 
ATOM   278  H  HG23  . VAL A 1 27  ? 33.63026  2.87189   4.70805  1.000 71.58287  ? 18   VAL A HG23  1 
ATOM   279  N  N     . LEU A 1 28  ? 30.69481  6.47019   5.13909  1.000 51.86563  ? 19   LEU A N     1 
ATOM   280  C  CA    . LEU A 1 28  ? 29.87251  7.67025   5.02115  1.000 54.16509  ? 19   LEU A CA    1 
ATOM   281  C  C     . LEU A 1 28  ? 29.66161  8.33698   6.37590  1.000 54.84331  ? 19   LEU A C     1 
ATOM   282  O  O     . LEU A 1 28  ? 29.70313  9.56906   6.48177  1.000 51.32536  ? 19   LEU A O     1 
ATOM   283  C  CB    . LEU A 1 28  ? 28.53208  7.31655   4.37920  1.000 56.23203  ? 19   LEU A CB    1 
ATOM   284  C  CG    . LEU A 1 28  ? 28.61669  6.84870   2.92515  1.000 61.79599  ? 19   LEU A CG    1 
ATOM   285  C  CD1   . LEU A 1 28  ? 27.27130  6.32254   2.45372  1.000 61.71338  ? 19   LEU A CD1   1 
ATOM   286  C  CD2   . LEU A 1 28  ? 29.09931  7.97776   2.02013  1.000 59.48876  ? 19   LEU A CD2   1 
ATOM   287  H  H     . LEU A 1 28  ? 30.28985  5.73768   4.94152  1.000 62.28198  ? 19   LEU A H     1 
ATOM   288  H  HA    . LEU A 1 28  ? 30.32612  8.30679   4.44673  1.000 65.04132  ? 19   LEU A HA    1 
ATOM   289  H  HB2   . LEU A 1 28  ? 28.12557  6.60104   4.89271  1.000 67.52166  ? 19   LEU A HB2   1 
ATOM   290  H  HB3   . LEU A 1 28  ? 27.96513  8.10334   4.40000  1.000 67.52166  ? 19   LEU A HB3   1 
ATOM   291  H  HG    . LEU A 1 28  ? 29.26001  6.12506   2.86687  1.000 74.19840  ? 19   LEU A HG    1 
ATOM   292  H  HD11  . LEU A 1 28  ? 27.33741  6.08112   1.51657  1.000 74.09927  ? 19   LEU A HD11  1 
ATOM   293  H  HD12  . LEU A 1 28  ? 27.03501  5.54291   2.98026  1.000 74.09927  ? 19   LEU A HD12  1 
ATOM   294  H  HD13  . LEU A 1 28  ? 26.60270  7.01554   2.57041  1.000 74.09927  ? 19   LEU A HD13  1 
ATOM   295  H  HD21  . LEU A 1 28  ? 29.07547  7.67592   1.09860  1.000 71.42973  ? 19   LEU A HD21  1 
ATOM   296  H  HD22  . LEU A 1 28  ? 28.51528  8.74406   2.13242  1.000 71.42973  ? 19   LEU A HD22  1 
ATOM   297  H  HD23  . LEU A 1 28  ? 30.00691  8.21456   2.26727  1.000 71.42973  ? 19   LEU A HD23  1 
ATOM   298  N  N     . ALA A 1 29  ? 29.42816  7.54136   7.42284  1.000 54.22016  ? 20   ALA A N     1 
ATOM   299  C  CA    . ALA A 1 29  ? 29.24243  8.10480   8.75643  1.000 58.21110  ? 20   ALA A CA    1 
ATOM   300  C  C     . ALA A 1 29  ? 30.47064  8.89180   9.19461  1.000 58.88305  ? 20   ALA A C     1 
ATOM   301  O  O     . ALA A 1 29  ? 30.36196  10.03546  9.65273  1.000 59.91993  ? 20   ALA A O     1 
ATOM   302  C  CB    . ALA A 1 29  ? 28.94082  6.99095   9.75823  1.000 51.89279  ? 20   ALA A CB    1 
ATOM   303  H  H     . ALA A 1 29  ? 29.37361  6.68387   7.38639  1.000 65.10741  ? 20   ALA A H     1 
ATOM   304  H  HA    . ALA A 1 29  ? 28.48416  8.70934   8.73504  1.000 69.89653  ? 20   ALA A HA    1 
ATOM   305  H  HB1   . ALA A 1 29  ? 28.80611  7.38293   10.63522 1.000 62.31457  ? 20   ALA A HB1   1 
ATOM   306  H  HB2   . ALA A 1 29  ? 28.13854  6.52312   9.47825  1.000 62.31457  ? 20   ALA A HB2   1 
ATOM   307  H  HB3   . ALA A 1 29  ? 29.69080  6.37626   9.78231  1.000 62.31457  ? 20   ALA A HB3   1 
ATOM   308  N  N     . ILE A 1 30  ? 31.65296  8.28780   9.06563  1.000 57.42965  ? 21   ILE A N     1 
ATOM   309  C  CA    . ILE A 1 30  ? 32.88223  8.95801   9.48168  1.000 57.22667  ? 21   ILE A CA    1 
ATOM   310  C  C     . ILE A 1 30  ? 33.07856  10.24651  8.69164  1.000 57.77776  ? 21   ILE A C     1 
ATOM   311  O  O     . ILE A 1 30  ? 33.32677  11.31426  9.26273  1.000 61.81659  ? 21   ILE A O     1 
ATOM   312  C  CB    . ILE A 1 30  ? 34.08635  8.01071   9.32451  1.000 57.10503  ? 21   ILE A CB    1 
ATOM   313  C  CG1   . ILE A 1 30  ? 33.91702  6.79055   10.23522 1.000 57.31878  ? 21   ILE A CG1   1 
ATOM   314  C  CG2   . ILE A 1 30  ? 35.38685  8.74586   9.63694  1.000 56.59091  ? 21   ILE A CG2   1 
ATOM   315  C  CD1   . ILE A 1 30  ? 34.90076  5.67069   9.96104  1.000 56.00423  ? 21   ILE A CD1   1 
ATOM   316  H  H     . ILE A 1 30  ? 31.76866  7.49877   8.74368  1.000 68.95880  ? 21   ILE A H     1 
ATOM   317  H  HA    . ILE A 1 30  ? 32.80346  9.19301   10.41948 1.000 68.71522  ? 21   ILE A HA    1 
ATOM   318  H  HB    . ILE A 1 30  ? 34.12447  7.70516   8.40468  1.000 68.56925  ? 21   ILE A HB    1 
ATOM   319  H  HG12  . ILE A 1 30  ? 34.03932  7.07099   11.15571 1.000 68.82575  ? 21   ILE A HG12  1 
ATOM   320  H  HG13  . ILE A 1 30  ? 33.02333  6.43377   10.11305 1.000 68.82575  ? 21   ILE A HG13  1 
ATOM   321  H  HG21  . ILE A 1 30  ? 36.11306  8.10356   9.66812  1.000 67.95231  ? 21   ILE A HG21  1 
ATOM   322  H  HG22  . ILE A 1 30  ? 35.55427  9.40092   8.94141  1.000 67.95231  ? 21   ILE A HG22  1 
ATOM   323  H  HG23  . ILE A 1 30  ? 35.30052  9.18944   10.49524 1.000 67.95231  ? 21   ILE A HG23  1 
ATOM   324  H  HD11  . ILE A 1 30  ? 34.68733  4.91605   10.53188 1.000 67.24829  ? 21   ILE A HD11  1 
ATOM   325  H  HD12  . ILE A 1 30  ? 34.83143  5.41055   9.02915  1.000 67.24829  ? 21   ILE A HD12  1 
ATOM   326  H  HD13  . ILE A 1 30  ? 35.79846  5.98544   10.15070 1.000 67.24829  ? 21   ILE A HD13  1 
ATOM   327  N  N     . LEU A 1 31  ? 32.97002  10.16600  7.36449  1.000 55.93512  ? 22   LEU A N     1 
ATOM   328  C  CA    . LEU A 1 31  ? 33.21280  11.33791  6.52886  1.000 61.20821  ? 22   LEU A CA    1 
ATOM   329  C  C     . LEU A 1 31  ? 32.26205  12.47785  6.87824  1.000 61.20271  ? 22   LEU A C     1 
ATOM   330  O  O     . LEU A 1 31  ? 32.69614  13.60264  7.15209  1.000 60.16022  ? 22   LEU A O     1 
ATOM   331  C  CB    . LEU A 1 31  ? 33.07456  10.96146  5.05409  1.000 66.22220  ? 22   LEU A CB    1 
ATOM   332  C  CG    . LEU A 1 31  ? 34.14723  10.02298  4.50040  1.000 67.27719  ? 22   LEU A CG    1 
ATOM   333  C  CD1   . LEU A 1 31  ? 33.80595  9.58967   3.08234  1.000 62.39617  ? 22   LEU A CD1   1 
ATOM   334  C  CD2   . LEU A 1 31  ? 35.51195  10.69463  4.54187  1.000 67.92213  ? 22   LEU A CD2   1 
ATOM   335  H  H     . LEU A 1 31  ? 32.76003  9.45404   6.93020  1.000 67.16536  ? 22   LEU A H     1 
ATOM   336  H  HA    . LEU A 1 31  ? 34.11932  11.64603  6.68437  1.000 73.49307  ? 22   LEU A HA    1 
ATOM   337  H  HB2   . LEU A 1 31  ? 32.21808  10.52259  4.93271  1.000 79.50986  ? 22   LEU A HB2   1 
ATOM   338  H  HB3   . LEU A 1 31  ? 33.10698  11.77660  4.52929  1.000 79.50986  ? 22   LEU A HB3   1 
ATOM   339  H  HG    . LEU A 1 31  ? 34.18421  9.22663   5.05299  1.000 80.77585  ? 22   LEU A HG    1 
ATOM   340  H  HD11  . LEU A 1 31  ? 34.50091  8.99593   2.75767  1.000 74.91862  ? 22   LEU A HD11  1 
ATOM   341  H  HD12  . LEU A 1 31  ? 32.95309  9.12765   3.08992  1.000 74.91862  ? 22   LEU A HD12  1 
ATOM   342  H  HD13  . LEU A 1 31  ? 33.75137  10.37561  2.51647  1.000 74.91862  ? 22   LEU A HD13  1 
ATOM   343  H  HD21  . LEU A 1 31  ? 36.14811  10.14753  4.05516  1.000 81.54978  ? 22   LEU A HD21  1 
ATOM   344  H  HD22  . LEU A 1 31  ? 35.44560  11.57034  4.13001  1.000 81.54978  ? 22   LEU A HD22  1 
ATOM   345  H  HD23  . LEU A 1 31  ? 35.79188  10.78421  5.46628  1.000 81.54978  ? 22   LEU A HD23  1 
ATOM   346  N  N     . GLY A 1 32  ? 30.95659  12.20760  6.86381  1.000 59.01244  ? 23   GLY A N     1 
ATOM   347  C  CA    . GLY A 1 32  ? 29.99284  13.27240  7.09105  1.000 61.42756  ? 23   GLY A CA    1 
ATOM   348  C  C     . GLY A 1 32  ? 30.14766  13.92178  8.45216  1.000 59.86845  ? 23   GLY A C     1 
ATOM   349  O  O     . GLY A 1 32  ? 30.16623  15.14893  8.57238  1.000 60.44740  ? 23   GLY A O     1 
ATOM   350  H  H     . GLY A 1 32  ? 30.61272  11.43125  6.72732  1.000 70.85814  ? 23   GLY A H     1 
ATOM   351  H  HA2   . GLY A 1 32  ? 30.10643  13.95655  6.41287  1.000 73.75628  ? 23   GLY A HA2   1 
ATOM   352  H  HA3   . GLY A 1 32  ? 29.09525  12.91026  7.02707  1.000 73.75628  ? 23   GLY A HA3   1 
ATOM   353  N  N     . ASN A 1 33  ? 30.26277  13.10506  9.49972  1.000 61.07096  ? 24   ASN A N     1 
ATOM   354  C  CA    . ASN A 1 33  ? 30.30438  13.65516  10.84970 1.000 60.83976  ? 24   ASN A CA    1 
ATOM   355  C  C     . ASN A 1 33  ? 31.64578  14.30709  11.15390 1.000 65.12016  ? 24   ASN A C     1 
ATOM   356  O  O     . ASN A 1 33  ? 31.70785  15.23915  11.96431 1.000 66.10460  ? 24   ASN A O     1 
ATOM   357  C  CB    . ASN A 1 33  ? 29.98776  12.56223  11.86575 1.000 54.10853  ? 24   ASN A CB    1 
ATOM   358  C  CG    . ASN A 1 33  ? 28.53449  12.13964  11.82007 1.000 55.13837  ? 24   ASN A CG    1 
ATOM   359  O  OD1   . ASN A 1 33  ? 27.69153  12.70124  12.51866 1.000 59.90991  ? 24   ASN A OD1   1 
ATOM   360  N  ND2   . ASN A 1 33  ? 28.22992  11.15455  10.98340 1.000 59.92250  ? 24   ASN A ND2   1 
ATOM   361  H  H     . ASN A 1 33  ? 30.31731  12.24792  9.45567  1.000 73.32837  ? 24   ASN A H     1 
ATOM   362  H  HA    . ASN A 1 33  ? 29.62368  14.34140  10.93103 1.000 73.05093  ? 24   ASN A HA    1 
ATOM   363  H  HB2   . ASN A 1 33  ? 30.53468  11.78385  11.67627 1.000 64.97345  ? 24   ASN A HB2   1 
ATOM   364  H  HB3   . ASN A 1 33  ? 30.17832  12.89244  12.75769 1.000 64.97345  ? 24   ASN A HB3   1 
ATOM   365  H  HD21  . ASN A 1 33  ? 27.41771  10.87877  10.92133 1.000 71.95021  ? 24   ASN A HD21  1 
ATOM   366  H  HD22  . ASN A 1 33  ? 28.84488  10.79232  10.50359 1.000 71.95021  ? 24   ASN A HD22  1 
ATOM   367  N  N     . VAL A 1 34  ? 32.72513  13.84212  10.52340 1.000 63.12805  ? 25   VAL A N     1 
ATOM   368  C  CA    . VAL A 1 34  ? 33.99068  14.56222  10.62556 1.000 66.62542  ? 25   VAL A CA    1 
ATOM   369  C  C     . VAL A 1 34  ? 33.85394  15.94488  10.00196 1.000 64.26063  ? 25   VAL A C     1 
ATOM   370  O  O     . VAL A 1 34  ? 34.42466  16.92605  10.49379 1.000 67.65887  ? 25   VAL A O     1 
ATOM   371  C  CB    . VAL A 1 34  ? 35.12454  13.75413  9.96901  1.000 66.58295  ? 25   VAL A CB    1 
ATOM   372  C  CG1   . VAL A 1 34  ? 36.33272  14.64486  9.71919  1.000 63.76130  ? 25   VAL A CG1   1 
ATOM   373  C  CG2   . VAL A 1 34  ? 35.50684  12.56691  10.84408 1.000 65.84682  ? 25   VAL A CG2   1 
ATOM   374  H  H     . VAL A 1 34  ? 32.74962  13.12969  10.04232 1.000 75.79688  ? 25   VAL A H     1 
ATOM   375  H  HA    . VAL A 1 34  ? 34.21166  14.67155  11.56370 1.000 79.99371  ? 25   VAL A HA    1 
ATOM   376  H  HB    . VAL A 1 34  ? 34.81595  13.41362  9.11477  1.000 79.94276  ? 25   VAL A HB    1 
ATOM   377  H  HG11  . VAL A 1 34  ? 37.11153  14.08617  9.57013  1.000 76.55677  ? 25   VAL A HG11  1 
ATOM   378  H  HG12  . VAL A 1 34  ? 36.16443  15.19325  8.93698  1.000 76.55677  ? 25   VAL A HG12  1 
ATOM   379  H  HG13  . VAL A 1 34  ? 36.47442  15.20973  10.49491 1.000 76.55677  ? 25   VAL A HG13  1 
ATOM   380  H  HG21  . VAL A 1 34  ? 36.16164  12.02660  10.37482 1.000 79.05940  ? 25   VAL A HG21  1 
ATOM   381  H  HG22  . VAL A 1 34  ? 35.88371  12.89560  11.67524 1.000 79.05940  ? 25   VAL A HG22  1 
ATOM   382  H  HG23  . VAL A 1 34  ? 34.71289  12.04028  11.02630 1.000 79.05940  ? 25   VAL A HG23  1 
ATOM   383  N  N     . LEU A 1 35  ? 33.08934  16.04459  8.91132  1.000 64.97053  ? 26   LEU A N     1 
ATOM   384  C  CA    . LEU A 1 35  ? 32.86053  17.33940  8.27960  1.000 65.41724  ? 26   LEU A CA    1 
ATOM   385  C  C     . LEU A 1 35  ? 32.07558  18.26657  9.19892  1.000 64.62231  ? 26   LEU A C     1 
ATOM   386  O  O     . LEU A 1 35  ? 32.36331  19.46682  9.26984  1.000 65.98881  ? 26   LEU A O     1 
ATOM   387  C  CB    . LEU A 1 35  ? 32.12794  17.14830  6.95057  1.000 71.21710  ? 26   LEU A CB    1 
ATOM   388  C  CG    . LEU A 1 35  ? 31.80921  18.40997  6.14285  1.000 73.28146  ? 26   LEU A CG    1 
ATOM   389  C  CD1   . LEU A 1 35  ? 33.05015  19.26930  5.94903  1.000 75.59727  ? 26   LEU A CD1   1 
ATOM   390  C  CD2   . LEU A 1 35  ? 31.19966  18.03980  4.79193  1.000 73.43907  ? 26   LEU A CD2   1 
ATOM   391  H  H     . LEU A 1 35  ? 32.69728  15.38453  8.52374  1.000 78.00785  ? 26   LEU A H     1 
ATOM   392  H  HA    . LEU A 1 35  ? 33.71627  17.75618  8.09278  1.000 78.54390  ? 26   LEU A HA    1 
ATOM   393  H  HB2   . LEU A 1 35  ? 32.67739  16.58252  6.38586  1.000 85.50373  ? 26   LEU A HB2   1 
ATOM   394  H  HB3   . LEU A 1 35  ? 31.28248  16.71060  7.13634  1.000 85.50373  ? 26   LEU A HB3   1 
ATOM   395  H  HG    . LEU A 1 35  ? 31.16199  18.93653  6.63757  1.000 87.98097  ? 26   LEU A HG    1 
ATOM   396  H  HD11  . LEU A 1 35  ? 32.82295  20.03138  5.39359  1.000 90.75994  ? 26   LEU A HD11  1 
ATOM   397  H  HD12  . LEU A 1 35  ? 33.36246  19.57305  6.81569  1.000 90.75994  ? 26   LEU A HD12  1 
ATOM   398  H  HD13  . LEU A 1 35  ? 33.73758  18.73844  5.51714  1.000 90.75994  ? 26   LEU A HD13  1 
ATOM   399  H  HD21  . LEU A 1 35  ? 31.01270  18.85251  4.29650  1.000 88.17009  ? 26   LEU A HD21  1 
ATOM   400  H  HD22  . LEU A 1 35  ? 31.83051  17.49064  4.30066  1.000 88.17009  ? 26   LEU A HD22  1 
ATOM   401  H  HD23  . LEU A 1 35  ? 30.37773  17.54668  4.94082  1.000 88.17009  ? 26   LEU A HD23  1 
ATOM   402  N  N     . VAL A 1 36  ? 31.08064  17.73067  9.90940  1.000 66.72472  ? 27   VAL A N     1 
ATOM   403  C  CA    . VAL A 1 36  ? 30.33022  18.54103  10.86628 1.000 65.62252  ? 27   VAL A CA    1 
ATOM   404  C  C     . VAL A 1 36  ? 31.26076  19.07243  11.94909 1.000 65.61133  ? 27   VAL A C     1 
ATOM   405  O  O     . VAL A 1 36  ? 31.22372  20.25748  12.30040 1.000 66.04607  ? 27   VAL A O     1 
ATOM   406  C  CB    . VAL A 1 36  ? 29.17337  17.72656  11.47383 1.000 67.41824  ? 27   VAL A CB    1 
ATOM   407  C  CG1   . VAL A 1 36  ? 28.59996  18.43972  12.69068 1.000 61.38784  ? 27   VAL A CG1   1 
ATOM   408  C  CG2   . VAL A 1 36  ? 28.08378  17.48709  10.43883 1.000 61.07375  ? 27   VAL A CG2   1 
ATOM   409  H  H     . VAL A 1 36  ? 30.82438  16.91146  9.85627  1.000 80.11288  ? 27   VAL A H     1 
ATOM   410  H  HA    . VAL A 1 36  ? 29.94899  19.29824  10.39489 1.000 78.79024  ? 27   VAL A HA    1 
ATOM   411  H  HB    . VAL A 1 36  ? 29.51668  16.86498  11.75794 1.000 80.94511  ? 27   VAL A HB    1 
ATOM   412  H  HG11  . VAL A 1 36  ? 27.73576  18.05449  12.90436 1.000 73.70863  ? 27   VAL A HG11  1 
ATOM   413  H  HG12  . VAL A 1 36  ? 29.20698  18.32576  13.43864 1.000 73.70863  ? 27   VAL A HG12  1 
ATOM   414  H  HG13  . VAL A 1 36  ? 28.50034  19.38268  12.48622 1.000 73.70863  ? 27   VAL A HG13  1 
ATOM   415  H  HG21  . VAL A 1 36  ? 27.37772  16.95692  10.84047 1.000 73.33172  ? 27   VAL A HG21  1 
ATOM   416  H  HG22  . VAL A 1 36  ? 27.73063  18.34255  10.14836 1.000 73.33172  ? 27   VAL A HG22  1 
ATOM   417  H  HG23  . VAL A 1 36  ? 28.46464  17.01271  9.68331  1.000 73.33172  ? 27   VAL A HG23  1 
ATOM   418  N  N     . CYS A 1 37  ? 32.10458  18.19843  12.50225 1.000 62.80646  ? 28   CYS A N     1 
ATOM   419  C  CA    . CYS A 1 37  ? 33.03988  18.63420  13.53405 1.000 67.43238  ? 28   CYS A CA    1 
ATOM   420  C  C     . CYS A 1 37  ? 33.97087  19.71861  13.00627 1.000 73.76042  ? 28   CYS A C     1 
ATOM   421  O  O     . CYS A 1 37  ? 34.21939  20.72192  13.68587 1.000 77.51131  ? 28   CYS A O     1 
ATOM   422  C  CB    . CYS A 1 37  ? 33.84830  17.44279  14.04918 1.000 69.39871  ? 28   CYS A CB    1 
ATOM   423  S  SG    . CYS A 1 37  ? 32.89212  16.22202  14.97873 1.000 62.09888  ? 28   CYS A SG    1 
ATOM   424  H  H     . CYS A 1 37  ? 32.15356  17.36381  12.30070 1.000 75.41096  ? 28   CYS A H     1 
ATOM   425  H  HA    . CYS A 1 37  ? 32.53629  19.00021  14.27791 1.000 80.96208  ? 28   CYS A HA    1 
ATOM   426  H  HB2   . CYS A 1 37  ? 34.24283  16.98710  13.28918 1.000 83.32167  ? 28   CYS A HB2   1 
ATOM   427  H  HB3   . CYS A 1 37  ? 34.54593  17.77492  14.63561 1.000 83.32167  ? 28   CYS A HB3   1 
ATOM   428  H  HG    . CYS A 1 37  ? 32.00280  15.81193  14.28523 1.000 74.56187  ? 28   CYS A HG    1 
ATOM   429  N  N     . TRP A 1 38  ? 34.49872  19.53127  11.79475 1.000 71.89538  ? 29   TRP A N     1 
ATOM   430  C  CA    . TRP A 1 38  ? 35.41009  20.51592  11.22211 1.000 73.39823  ? 29   TRP A CA    1 
ATOM   431  C  C     . TRP A 1 38  ? 34.70736  21.84885  10.99675 1.000 74.84388  ? 29   TRP A C     1 
ATOM   432  O  O     . TRP A 1 38  ? 35.29104  22.91499  11.22748 1.000 76.66707  ? 29   TRP A O     1 
ATOM   433  C  CB    . TRP A 1 38  ? 35.98435  19.97871  9.91220  1.000 72.05863  ? 29   TRP A CB    1 
ATOM   434  C  CG    . TRP A 1 38  ? 37.24989  20.64749  9.47333  1.000 80.81750  ? 29   TRP A CG    1 
ATOM   435  C  CD1   . TRP A 1 38  ? 37.83039  21.75259  10.02283 1.000 85.89872  ? 29   TRP A CD1   1 
ATOM   436  C  CD2   . TRP A 1 38  ? 38.09813  20.24511  8.39179  1.000 82.26477  ? 29   TRP A CD2   1 
ATOM   437  N  NE1   . TRP A 1 38  ? 38.98572  22.06559  9.34875  1.000 85.49443  ? 29   TRP A NE1   1 
ATOM   438  C  CE2   . TRP A 1 38  ? 39.17251  21.15450  8.34284  1.000 84.12341  ? 29   TRP A CE2   1 
ATOM   439  C  CE3   . TRP A 1 38  ? 38.05222  19.20431  7.45951  1.000 84.81200  ? 29   TRP A CE3   1 
ATOM   440  C  CZ2   . TRP A 1 38  ? 40.19154  21.05521  7.39892  1.000 85.84992  ? 29   TRP A CZ2   1 
ATOM   441  C  CZ3   . TRP A 1 38  ? 39.06435  19.10747  6.52323  1.000 90.28836  ? 29   TRP A CZ3   1 
ATOM   442  C  CH2   . TRP A 1 38  ? 40.11974  20.02734  6.49991  1.000 84.65373  ? 29   TRP A CH2   1 
ATOM   443  H  H     . TRP A 1 38  ? 34.34624  18.85073  11.29155 1.000 86.31767  ? 29   TRP A H     1 
ATOM   444  H  HA    . TRP A 1 38  ? 36.14495  20.66824  11.83667 1.000 88.12109  ? 29   TRP A HA    1 
ATOM   445  H  HB2   . TRP A 1 38  ? 36.17440  19.03384  10.02177 1.000 86.51358  ? 29   TRP A HB2   1 
ATOM   446  H  HB3   . TRP A 1 38  ? 35.32669  20.10564  9.21058  1.000 86.51358  ? 29   TRP A HB3   1 
ATOM   447  H  HD1   . TRP A 1 38  ? 37.49290  22.22577  10.74884 1.000 103.12169 ? 29   TRP A HD1   1 
ATOM   448  H  HE1   . TRP A 1 38  ? 39.50669  22.72572  9.52882  1.000 102.63653 ? 29   TRP A HE1   1 
ATOM   449  H  HE3   . TRP A 1 38  ? 37.35460  18.58938  7.46912  1.000 101.81762 ? 29   TRP A HE3   1 
ATOM   450  H  HZ2   . TRP A 1 38  ? 40.89390  21.66452  7.38066  1.000 103.06312 ? 29   TRP A HZ2   1 
ATOM   451  H  HZ3   . TRP A 1 38  ? 39.04403  18.41941  5.89788  1.000 108.38924 ? 29   TRP A HZ3   1 
ATOM   452  H  HH2   . TRP A 1 38  ? 40.78705  19.93720  5.85844  1.000 101.62769 ? 29   TRP A HH2   1 
ATOM   453  N  N     . ALA A 1 39  ? 33.45167  21.80930  10.54599 1.000 73.92752  ? 30   ALA A N     1 
ATOM   454  C  CA    . ALA A 1 39  ? 32.70729  23.04278  10.31618 1.000 72.82905  ? 30   ALA A CA    1 
ATOM   455  C  C     . ALA A 1 39  ? 32.55214  23.83654  11.60768 1.000 76.97067  ? 30   ALA A C     1 
ATOM   456  O  O     . ALA A 1 39  ? 32.79160  25.04898  11.63810 1.000 76.64523  ? 30   ALA A O     1 
ATOM   457  C  CB    . ALA A 1 39  ? 31.33968  22.72286  9.71154  1.000 74.96617  ? 30   ALA A CB    1 
ATOM   458  H  H     . ALA A 1 39  ? 33.01523  21.08990  10.36832 1.000 88.75625  ? 30   ALA A H     1 
ATOM   459  H  HA    . ALA A 1 39  ? 33.19625  23.59067  9.68243  1.000 87.43808  ? 30   ALA A HA    1 
ATOM   460  H  HB1   . ALA A 1 39  ? 30.86037  23.55211  9.55823  1.000 90.00262  ? 30   ALA A HB1   1 
ATOM   461  H  HB2   . ALA A 1 39  ? 31.46742  22.25452  8.87175  1.000 90.00262  ? 30   ALA A HB2   1 
ATOM   462  H  HB3   . ALA A 1 39  ? 30.84393  22.16373  10.33001 1.000 90.00262  ? 30   ALA A HB3   1 
ATOM   463  N  N     . VAL A 1 40  ? 32.15092  23.16634  12.68972 1.000 77.80130  ? 31   VAL A N     1 
ATOM   464  C  CA    . VAL A 1 40  ? 31.98055  23.85626  13.96453 1.000 78.75962  ? 31   VAL A CA    1 
ATOM   465  C  C     . VAL A 1 40  ? 33.32118  24.36827  14.47862 1.000 80.97766  ? 31   VAL A C     1 
ATOM   466  O  O     . VAL A 1 40  ? 33.40070  25.44855  15.07587 1.000 84.47642  ? 31   VAL A O     1 
ATOM   467  C  CB    . VAL A 1 40  ? 31.30230  22.92547  14.98808 1.000 81.98209  ? 31   VAL A CB    1 
ATOM   468  C  CG1   . VAL A 1 40  ? 31.19205  23.60858  16.34665 1.000 74.81693  ? 31   VAL A CG1   1 
ATOM   469  C  CG2   . VAL A 1 40  ? 29.92759  22.49333  14.49245 1.000 73.41003  ? 31   VAL A CG2   1 
ATOM   470  H  H     . VAL A 1 40  ? 31.97389  22.32502  12.71062 1.000 93.40477  ? 31   VAL A H     1 
ATOM   471  H  HA    . VAL A 1 40  ? 31.40204  24.62202  13.82366 1.000 94.55476  ? 31   VAL A HA    1 
ATOM   472  H  HB    . VAL A 1 40  ? 31.84854  22.13092  15.09398 1.000 98.42173  ? 31   VAL A HB    1 
ATOM   473  H  HG11  . VAL A 1 40  ? 30.62244  23.07535  16.92295 1.000 89.82353  ? 31   VAL A HG11  1 
ATOM   474  H  HG12  . VAL A 1 40  ? 32.07770  23.68395  16.73503 1.000 89.82353  ? 31   VAL A HG12  1 
ATOM   475  H  HG13  . VAL A 1 40  ? 30.80750  24.49091  16.22620 1.000 89.82353  ? 31   VAL A HG13  1 
ATOM   476  H  HG21  . VAL A 1 40  ? 29.50692  21.94101  15.16985 1.000 88.13525  ? 31   VAL A HG21  1 
ATOM   477  H  HG22  . VAL A 1 40  ? 29.38867  23.28287  14.32786 1.000 88.13525  ? 31   VAL A HG22  1 
ATOM   478  H  HG23  . VAL A 1 40  ? 30.03253  21.98745  13.67149 1.000 88.13525  ? 31   VAL A HG23  1 
ATOM   479  N  N     . TRP A 1 41  ? 34.39527  23.60819  14.25277 1.000 79.64944  ? 32   TRP A N     1 
ATOM   480  C  CA    . TRP A 1 41  ? 35.69582  23.98791  14.79470 1.000 85.18095  ? 32   TRP A CA    1 
ATOM   481  C  C     . TRP A 1 41  ? 36.25268  25.23809  14.12283 1.000 86.27428  ? 32   TRP A C     1 
ATOM   482  O  O     . TRP A 1 41  ? 36.93958  26.03135  14.77670 1.000 92.64857  ? 32   TRP A O     1 
ATOM   483  C  CB    . TRP A 1 41  ? 36.67675  22.82005  14.65647 1.000 91.28619  ? 32   TRP A CB    1 
ATOM   484  C  CG    . TRP A 1 41  ? 38.11981  23.21512  14.77538 1.000 97.51773  ? 32   TRP A CG    1 
ATOM   485  C  CD1   . TRP A 1 41  ? 38.94140  23.60830  13.76263 1.000 99.36547  ? 32   TRP A CD1   1 
ATOM   486  C  CD2   . TRP A 1 41  ? 38.91436  23.24730  15.96984 1.000 98.55864  ? 32   TRP A CD2   1 
ATOM   487  N  NE1   . TRP A 1 41  ? 40.19374  23.89253  14.24706 1.000 100.79114 ? 32   TRP A NE1   1 
ATOM   488  C  CE2   . TRP A 1 41  ? 40.20537  23.67622  15.59948 1.000 102.07714 ? 32   TRP A CE2   1 
ATOM   489  C  CE3   . TRP A 1 41  ? 38.66034  22.95710  17.31433 1.000 100.06555 ? 32   TRP A CE3   1 
ATOM   490  C  CZ2   . TRP A 1 41  ? 41.23892  23.82241  16.52337 1.000 101.06848 ? 32   TRP A CZ2   1 
ATOM   491  C  CZ3   . TRP A 1 41  ? 39.69002  23.10348  18.23164 1.000 98.75505  ? 32   TRP A CZ3   1 
ATOM   492  C  CH2   . TRP A 1 41  ? 40.96219  23.53241  17.83083 1.000 97.50138  ? 32   TRP A CH2   1 
ATOM   493  H  H     . TRP A 1 41  ? 34.39609  22.87955  13.79596 1.000 95.62254  ? 32   TRP A H     1 
ATOM   494  H  HA    . TRP A 1 41  ? 35.59392  24.18669  15.73863 1.000 102.26036 ? 32   TRP A HA    1 
ATOM   495  H  HB2   . TRP A 1 41  ? 36.48992  22.17308  15.35462 1.000 109.58665 ? 32   TRP A HB2   1 
ATOM   496  H  HB3   . TRP A 1 41  ? 36.55373  22.41247  13.78490 1.000 109.58665 ? 32   TRP A HB3   1 
ATOM   497  H  HD1   . TRP A 1 41  ? 38.68960  23.67471  12.86983 1.000 119.28178 ? 32   TRP A HD1   1 
ATOM   498  H  HE1   . TRP A 1 41  ? 40.86210  24.16242  13.77796 1.000 120.99258 ? 32   TRP A HE1   1 
ATOM   499  H  HE3   . TRP A 1 41  ? 37.81835  22.67188  17.58745 1.000 120.12187 ? 32   TRP A HE3   1 
ATOM   500  H  HZ2   . TRP A 1 41  ? 42.08460  24.10641  16.26056 1.000 121.32539 ? 32   TRP A HZ2   1 
ATOM   501  H  HZ3   . TRP A 1 41  ? 39.53340  22.91362  19.12848 1.000 118.54927 ? 32   TRP A HZ3   1 
ATOM   502  H  HH2   . TRP A 1 41  ? 41.63347  23.62191  18.46823 1.000 117.04487 ? 32   TRP A HH2   1 
ATOM   503  N  N     . LEU A 1 42  ? 35.97397  25.43902  12.83333 1.000 87.07463  ? 33   LEU A N     1 
ATOM   504  C  CA    . LEU A 1 42  ? 36.50966  26.60056  12.13201 1.000 84.90145  ? 33   LEU A CA    1 
ATOM   505  C  C     . LEU A 1 42  ? 35.60067  27.82189  12.22500 1.000 86.62336  ? 33   LEU A C     1 
ATOM   506  O  O     . LEU A 1 42  ? 36.08621  28.93398  12.45629 1.000 89.56193  ? 33   LEU A O     1 
ATOM   507  C  CB    . LEU A 1 42  ? 36.75644  26.27676  10.65439 1.000 84.59466  ? 33   LEU A CB    1 
ATOM   508  C  CG    . LEU A 1 42  ? 37.91491  25.35151  10.26799 1.000 86.23889  ? 33   LEU A CG    1 
ATOM   509  C  CD1   . LEU A 1 42  ? 38.27230  25.56125  8.79605  1.000 83.62669  ? 33   LEU A CD1   1 
ATOM   510  C  CD2   . LEU A 1 42  ? 39.15353  25.54490  11.12820 1.000 86.68959  ? 33   LEU A CD2   1 
ATOM   511  H  H     . LEU A 1 42  ? 35.48347  24.92267  12.35124 1.000 104.53277 ? 33   LEU A H     1 
ATOM   512  H  HA    . LEU A 1 42  ? 37.36049  26.82159  12.54205 1.000 101.92495 ? 33   LEU A HA    1 
ATOM   513  H  HB2   . LEU A 1 42  ? 35.95008  25.86058  10.31163 1.000 101.55680 ? 33   LEU A HB2   1 
ATOM   514  H  HB3   . LEU A 1 42  ? 36.91584  27.11744  10.19750 1.000 101.55680 ? 33   LEU A HB3   1 
ATOM   515  H  HG    . LEU A 1 42  ? 37.61822  24.43994  10.41607 1.000 103.52988 ? 33   LEU A HG    1 
ATOM   516  H  HD11  . LEU A 1 42  ? 38.94621  24.91258  8.53917  1.000 100.39524 ? 33   LEU A HD11  1 
ATOM   517  H  HD12  . LEU A 1 42  ? 37.47481  25.44076  8.25717  1.000 100.39524 ? 33   LEU A HD12  1 
ATOM   518  H  HD13  . LEU A 1 42  ? 38.61731  26.46034  8.67985  1.000 100.39524 ? 33   LEU A HD13  1 
ATOM   519  H  HD21  . LEU A 1 42  ? 39.78464  24.83337  10.93760 1.000 104.07072 ? 33   LEU A HD21  1 
ATOM   520  H  HD22  . LEU A 1 42  ? 39.55154  26.40463  10.91998 1.000 104.07072 ? 33   LEU A HD22  1 
ATOM   521  H  HD23  . LEU A 1 42  ? 38.89626  25.51722  12.06305 1.000 104.07072 ? 33   LEU A HD23  1 
ATOM   522  N  N     . ASN A 1 43  ? 34.29529  27.64633  12.04423 1.000 83.32196  ? 34   ASN A N     1 
ATOM   523  C  CA    . ASN A 1 43  ? 33.37264  28.77081  11.95612 1.000 88.06606  ? 34   ASN A CA    1 
ATOM   524  C  C     . ASN A 1 43  ? 32.91328  29.17208  13.35296 1.000 87.77602  ? 34   ASN A C     1 
ATOM   525  O  O     . ASN A 1 43  ? 32.31510  28.36466  14.07216 1.000 87.95283  ? 34   ASN A O     1 
ATOM   526  C  CB    . ASN A 1 43  ? 32.17535  28.41380  11.07709 1.000 83.46688  ? 34   ASN A CB    1 
ATOM   527  C  CG    . ASN A 1 43  ? 31.36503  29.62765  10.68105 1.000 85.83133  ? 34   ASN A CG    1 
ATOM   528  O  OD1   . ASN A 1 43  ? 31.27502  30.59873  11.43128 1.000 93.25859  ? 34   ASN A OD1   1 
ATOM   529  N  ND2   . ASN A 1 43  ? 30.77341  29.58231  9.49377  1.000 84.63709  ? 34   ASN A ND2   1 
ATOM   530  H  H     . ASN A 1 43  ? 33.91716  26.87759  11.96907 1.000 100.02957 ? 34   ASN A H     1 
ATOM   531  H  HA    . ASN A 1 43  ? 33.83105  29.52874  11.56078 1.000 105.72249 ? 34   ASN A HA    1 
ATOM   532  H  HB2   . ASN A 1 43  ? 32.49347  27.98674  10.26634 1.000 100.20348 ? 34   ASN A HB2   1 
ATOM   533  H  HB3   . ASN A 1 43  ? 31.59357  27.80942  11.56408 1.000 100.20348 ? 34   ASN A HB3   1 
ATOM   534  H  HD21  . ASN A 1 43  ? 30.86227  28.88714  8.99533  1.000 101.60773 ? 34   ASN A HD21  1 
ATOM   535  H  HD22  . ASN A 1 43  ? 30.30122  30.24811  9.22293  1.000 101.60773 ? 34   ASN A HD22  1 
ATOM   536  N  N     . SER A 1 44  ? 33.18986  30.42300  13.73098 1.000 88.22250  ? 35   SER A N     1 
ATOM   537  C  CA    . SER A 1 44  ? 32.74465  30.93008  15.02299 1.000 88.96976  ? 35   SER A CA    1 
ATOM   538  C  C     . SER A 1 44  ? 31.24317  31.18162  15.06202 1.000 88.34708  ? 35   SER A C     1 
ATOM   539  O  O     . SER A 1 44  ? 30.65646  31.17322  16.14940 1.000 88.93394  ? 35   SER A O     1 
ATOM   540  C  CB    . SER A 1 44  ? 33.49208  32.21869  15.36981 1.000 91.77599  ? 35   SER A CB    1 
ATOM   541  O  OG    . SER A 1 44  ? 34.63197  31.94701  16.16653 1.000 90.46407  ? 35   SER A OG    1 
ATOM   542  H  H     . SER A 1 44  ? 33.63043  30.99124  13.25918 1.000 105.91021 ? 35   SER A H     1 
ATOM   543  H  HA    . SER A 1 44  ? 32.95466  30.26873  15.70078 1.000 106.80692 ? 35   SER A HA    1 
ATOM   544  H  HB2   . SER A 1 44  ? 33.77719  32.64829  14.54820 1.000 110.17440 ? 35   SER A HB2   1 
ATOM   545  H  HB3   . SER A 1 44  ? 32.89662  32.80552  15.86169 1.000 110.17440 ? 35   SER A HB3   1 
ATOM   546  H  HG    . SER A 1 44  ? 35.00019  32.66630  16.39596 1.000 108.60010 ? 35   SER A HG    1 
ATOM   547  N  N     . ASN A 1 45  ? 30.60949  31.41191  13.90910 1.000 88.55304  ? 36   ASN A N     1 
ATOM   548  C  CA    . ASN A 1 45  ? 29.15812  31.54853  13.87813 1.000 89.80598  ? 36   ASN A CA    1 
ATOM   549  C  C     . ASN A 1 45  ? 28.45349  30.23891  14.20615 1.000 89.54777  ? 36   ASN A C     1 
ATOM   550  O  O     . ASN A 1 45  ? 27.26004  30.25422  14.52677 1.000 87.53860  ? 36   ASN A O     1 
ATOM   551  C  CB    . ASN A 1 45  ? 28.70006  32.04890  12.50713 1.000 92.51268  ? 36   ASN A CB    1 
ATOM   552  C  CG    . ASN A 1 45  ? 29.03584  33.50964  12.27587 1.000 94.97222  ? 36   ASN A CG    1 
ATOM   553  O  OD1   . ASN A 1 45  ? 29.80787  34.10881  13.02491 1.000 94.06247  ? 36   ASN A OD1   1 
ATOM   554  N  ND2   . ASN A 1 45  ? 28.45534  34.09080  11.23166 1.000 93.28330  ? 36   ASN A ND2   1 
ATOM   555  H  H     . ASN A 1 45  ? 30.99373  31.49157  13.14385 1.000 106.30686 ? 36   ASN A H     1 
ATOM   556  H  HA    . ASN A 1 45  ? 28.89647  32.20910  14.53849 1.000 107.81039 ? 36   ASN A HA    1 
ATOM   557  H  HB2   . ASN A 1 45  ? 29.13870  31.52705  11.81708 1.000 111.05843 ? 36   ASN A HB2   1 
ATOM   558  H  HB3   . ASN A 1 45  ? 27.73782  31.94745  12.43855 1.000 111.05843 ? 36   ASN A HB3   1 
ATOM   559  H  HD21  . ASN A 1 45  ? 27.92193  33.63973  10.73005 1.000 111.98317 ? 36   ASN A HD21  1 
ATOM   560  H  HD22  . ASN A 1 45  ? 28.61299  34.91806  11.05733 1.000 111.98317 ? 36   ASN A HD22  1 
ATOM   561  N  N     . LEU A 1 46  ? 29.16034  29.11259  14.12629 1.000 88.05021  ? 37   LEU A N     1 
ATOM   562  C  CA    . LEU A 1 46  ? 28.61592  27.81213  14.48569 1.000 83.77126  ? 37   LEU A CA    1 
ATOM   563  C  C     . LEU A 1 46  ? 29.01779  27.37045  15.88665 1.000 80.42673  ? 37   LEU A C     1 
ATOM   564  O  O     . LEU A 1 46  ? 28.60144  26.29357  16.32381 1.000 79.69798  ? 37   LEU A O     1 
ATOM   565  C  CB    . LEU A 1 46  ? 29.06527  26.75560  13.47041 1.000 86.11062  ? 37   LEU A CB    1 
ATOM   566  C  CG    . LEU A 1 46  ? 28.49195  26.86748  12.05618 1.000 81.03924  ? 37   LEU A CG    1 
ATOM   567  C  CD1   . LEU A 1 46  ? 29.19521  25.89264  11.12257 1.000 75.43484  ? 37   LEU A CD1   1 
ATOM   568  C  CD2   . LEU A 1 46  ? 26.99137  26.61464  12.05600 1.000 75.22299  ? 37   LEU A CD2   1 
ATOM   569  H  H     . LEU A 1 46  ? 29.97729  29.07894  13.85974 1.000 105.70347 ? 37   LEU A H     1 
ATOM   570  H  HA    . LEU A 1 46  ? 27.64779  27.86453  14.45578 1.000 100.56873 ? 37   LEU A HA    1 
ATOM   571  H  HB2   . LEU A 1 46  ? 30.03043  26.80962  13.39006 1.000 103.37596 ? 37   LEU A HB2   1 
ATOM   572  H  HB3   . LEU A 1 46  ? 28.80903  25.88466  13.81203 1.000 103.37596 ? 37   LEU A HB3   1 
ATOM   573  H  HG    . LEU A 1 46  ? 28.64084  27.76829  11.72865 1.000 97.29030  ? 37   LEU A HG    1 
ATOM   574  H  HD11  . LEU A 1 46  ? 28.80791  25.96876  10.23651 1.000 90.56502  ? 37   LEU A HD11  1 
ATOM   575  H  HD12  . LEU A 1 46  ? 30.13966  26.11149  11.09066 1.000 90.56502  ? 37   LEU A HD12  1 
ATOM   576  H  HD13  . LEU A 1 46  ? 29.07582  24.99087  11.45941 1.000 90.56502  ? 37   LEU A HD13  1 
ATOM   577  H  HD21  . LEU A 1 46  ? 26.67183  26.61107  11.14015 1.000 90.31081  ? 37   LEU A HD21  1 
ATOM   578  H  HD22  . LEU A 1 46  ? 26.81581  25.75562  12.47093 1.000 90.31081  ? 37   LEU A HD22  1 
ATOM   579  H  HD23  . LEU A 1 46  ? 26.55224  27.31981  12.55680 1.000 90.31081  ? 37   LEU A HD23  1 
ATOM   580  N  N     . GLN A 1 47  ? 29.81028  28.16926  16.59965 1.000 81.10880  ? 38   GLN A N     1 
ATOM   581  C  CA    . GLN A 1 47  ? 30.29080  27.80238  17.93172 1.000 82.45667  ? 38   GLN A CA    1 
ATOM   582  C  C     . GLN A 1 47  ? 29.32228  28.35652  18.96810 1.000 85.15021  ? 38   GLN A C     1 
ATOM   583  O  O     . GLN A 1 47  ? 29.47400  29.47408  19.46338 1.000 85.57108  ? 38   GLN A O     1 
ATOM   584  C  CB    . GLN A 1 47  ? 31.70755  28.31709  18.15085 1.000 87.23631  ? 38   GLN A CB    1 
ATOM   585  C  CG    . GLN A 1 47  ? 32.74650  27.61245  17.29763 1.000 86.20438  ? 38   GLN A CG    1 
ATOM   586  C  CD    . GLN A 1 47  ? 34.11799  28.24586  17.40060 1.000 86.53732  ? 38   GLN A CD    1 
ATOM   587  O  OE1   . GLN A 1 47  ? 34.34669  29.13186  18.22439 1.000 84.17944  ? 38   GLN A OE1   1 
ATOM   588  N  NE2   . GLN A 1 47  ? 35.04057  27.79556  16.55812 1.000 83.20467  ? 38   GLN A NE2   1 
ATOM   589  H  H     . GLN A 1 47  ? 30.08685  28.93789  16.33071 1.000 97.37378  ? 38   GLN A H     1 
ATOM   590  H  HA    . GLN A 1 47  ? 30.29611  26.83564  18.01106 1.000 98.99122  ? 38   GLN A HA    1 
ATOM   591  H  HB2   . GLN A 1 47  ? 31.73443  29.26173  17.93214 1.000 104.72679 ? 38   GLN A HB2   1 
ATOM   592  H  HB3   . GLN A 1 47  ? 31.94787  28.18500  19.08128 1.000 104.72679 ? 38   GLN A HB3   1 
ATOM   593  H  HG2   . GLN A 1 47  ? 32.82003  26.68962  17.58726 1.000 103.48848 ? 38   GLN A HG2   1 
ATOM   594  H  HG3   . GLN A 1 47  ? 32.46909  27.64755  16.36881 1.000 103.48848 ? 38   GLN A HG3   1 
ATOM   595  H  HE21  . GLN A 1 47  ? 34.84288  27.17679  15.99452 1.000 99.88882  ? 38   GLN A HE21  1 
ATOM   596  H  HE22  . GLN A 1 47  ? 35.83571  28.12274  16.57615 1.000 99.88882  ? 38   GLN A HE22  1 
ATOM   597  N  N     . ASN A 1 48  ? 28.30869  27.55893  19.29771 1.000 82.89777  ? 39   ASN A N     1 
ATOM   598  C  CA    . ASN A 1 48  ? 27.35065  27.89483  20.33889 1.000 87.18462  ? 39   ASN A CA    1 
ATOM   599  C  C     . ASN A 1 48  ? 27.04183  26.63059  21.13093 1.000 81.87385  ? 39   ASN A C     1 
ATOM   600  O  O     . ASN A 1 48  ? 27.57278  25.55079  20.85121 1.000 78.61546  ? 39   ASN A O     1 
ATOM   601  C  CB    . ASN A 1 48  ? 26.07805  28.51138  19.74749 1.000 75.95456  ? 39   ASN A CB    1 
ATOM   602  C  CG    . ASN A 1 48  ? 25.49234  27.67596  18.63005 1.000 80.44746  ? 39   ASN A CG    1 
ATOM   603  O  OD1   . ASN A 1 48  ? 24.83169  26.66626  18.87435 1.000 78.84260  ? 39   ASN A OD1   1 
ATOM   604  N  ND2   . ASN A 1 48  ? 25.72839  28.09541  17.39252 1.000 83.16537  ? 39   ASN A ND2   1 
ATOM   605  H  H     . ASN A 1 48  ? 28.15433  26.80100  18.92178 1.000 99.52054  ? 39   ASN A H     1 
ATOM   606  H  HA    . ASN A 1 48  ? 27.74630  28.54567  20.93954 1.000 104.66475 ? 39   ASN A HA    1 
ATOM   607  H  HB2   . ASN A 1 48  ? 25.40983  28.58974  20.44623 1.000 91.18868  ? 39   ASN A HB2   1 
ATOM   608  H  HB3   . ASN A 1 48  ? 26.28781  29.38804  19.38921 1.000 91.18868  ? 39   ASN A HB3   1 
ATOM   609  H  HD21  . ASN A 1 48  ? 25.41711  27.65514  16.72255 1.000 99.84166  ? 39   ASN A HD21  1 
ATOM   610  H  HD22  . ASN A 1 48  ? 26.19256  28.80734  17.26099 1.000 99.84166  ? 39   ASN A HD22  1 
ATOM   611  N  N     . VAL A 1 49  ? 26.17230  26.76924  22.13276 1.000 85.67787  ? 40   VAL A N     1 
ATOM   612  C  CA    . VAL A 1 49  ? 25.82274  25.62778  22.97351 1.000 80.98843  ? 40   VAL A CA    1 
ATOM   613  C  C     . VAL A 1 49  ? 25.10961  24.56473  22.14896 1.000 74.68675  ? 40   VAL A C     1 
ATOM   614  O  O     . VAL A 1 49  ? 25.45184  23.37690  22.19952 1.000 70.56845  ? 40   VAL A O     1 
ATOM   615  C  CB    . VAL A 1 49  ? 24.96174  26.08425  24.16491 1.000 83.63981  ? 40   VAL A CB    1 
ATOM   616  C  CG1   . VAL A 1 49  ? 24.62164  24.89918  25.05258 1.000 83.22959  ? 40   VAL A CG1   1 
ATOM   617  C  CG2   . VAL A 1 49  ? 25.67874  27.17374  24.95170 1.000 88.70691  ? 40   VAL A CG2   1 
ATOM   618  H  H     . VAL A 1 49  ? 25.77676  27.50339  22.34294 1.000 102.85666 ? 40   VAL A H     1 
ATOM   619  H  HA    . VAL A 1 49  ? 26.64013  25.23977  23.32311 1.000 97.22933  ? 40   VAL A HA    1 
ATOM   620  H  HB    . VAL A 1 49  ? 24.12959  26.45753  23.83463 1.000 100.41098 ? 40   VAL A HB    1 
ATOM   621  H  HG11  . VAL A 1 49  ? 24.28554  25.22667  25.90151 1.000 99.91873  ? 40   VAL A HG11  1 
ATOM   622  H  HG12  . VAL A 1 49  ? 23.94444  24.36042  24.61435 1.000 99.91873  ? 40   VAL A HG12  1 
ATOM   623  H  HG13  . VAL A 1 49  ? 25.42286  24.37141  25.19544 1.000 99.91873  ? 40   VAL A HG13  1 
ATOM   624  H  HG21  . VAL A 1 49  ? 25.19720  27.33538  25.77807 1.000 106.49150 ? 40   VAL A HG21  1 
ATOM   625  H  HG22  . VAL A 1 49  ? 26.58207  26.87945  25.14738 1.000 106.49150 ? 40   VAL A HG22  1 
ATOM   626  H  HG23  . VAL A 1 49  ? 25.70291  27.98403  24.41902 1.000 106.49150 ? 40   VAL A HG23  1 
ATOM   627  N  N     . THR A 1 50  ? 24.10337  24.97999  21.37733 1.000 74.49127  ? 41   THR A N     1 
ATOM   628  C  CA    . THR A 1 50  ? 23.33930  24.03549  20.57120 1.000 74.66243  ? 41   THR A CA    1 
ATOM   629  C  C     . THR A 1 50  ? 24.25844  23.19787  19.69088 1.000 73.78733  ? 41   THR A C     1 
ATOM   630  O  O     . THR A 1 50  ? 24.11913  21.97122  19.61392 1.000 71.80337  ? 41   THR A O     1 
ATOM   631  C  CB    . THR A 1 50  ? 22.32036  24.78944  19.71530 1.000 73.35412  ? 41   THR A CB    1 
ATOM   632  O  OG1   . THR A 1 50  ? 21.77431  25.87905  20.46923 1.000 78.19172  ? 41   THR A OG1   1 
ATOM   633  C  CG2   . THR A 1 50  ? 21.19476  23.85842  19.28422 1.000 73.58531  ? 41   THR A CG2   1 
ATOM   634  H  H     . THR A 1 50  ? 23.84652  25.79753  21.30474 1.000 89.43273  ? 41   THR A H     1 
ATOM   635  H  HA    . THR A 1 50  ? 22.85670  23.43644  21.16207 1.000 89.63813  ? 41   THR A HA    1 
ATOM   636  H  HB    . THR A 1 50  ? 22.75512  25.13325  18.91925 1.000 88.06816  ? 41   THR A HB    1 
ATOM   637  H  HG1   . THR A 1 50  ? 21.23289  26.31311  19.99589 1.000 93.87327  ? 41   THR A HG1   1 
ATOM   638  H  HG21  . THR A 1 50  ? 20.56804  24.33552  18.71809 1.000 88.34558  ? 41   THR A HG21  1 
ATOM   639  H  HG22  . THR A 1 50  ? 21.55698  23.10693  18.78929 1.000 88.34558  ? 41   THR A HG22  1 
ATOM   640  H  HG23  . THR A 1 50  ? 20.72367  23.52439  20.06359 1.000 88.34558  ? 41   THR A HG23  1 
ATOM   641  N  N     . ASN A 1 51  ? 25.21103  23.84386  19.01930 1.000 74.59512  ? 42   ASN A N     1 
ATOM   642  C  CA    . ASN A 1 51  ? 26.12139  23.11967  18.14395 1.000 73.20876  ? 42   ASN A CA    1 
ATOM   643  C  C     . ASN A 1 51  ? 27.17427  22.33471  18.91280 1.000 69.63630  ? 42   ASN A C     1 
ATOM   644  O  O     . ASN A 1 51  ? 27.83947  21.47758  18.32176 1.000 69.18580  ? 42   ASN A O     1 
ATOM   645  C  CB    . ASN A 1 51  ? 26.79909  24.08511  17.16967 1.000 76.79334  ? 42   ASN A CB    1 
ATOM   646  C  CG    . ASN A 1 51  ? 25.91236  24.43528  15.99012 1.000 77.18767  ? 42   ASN A CG    1 
ATOM   647  O  OD1   . ASN A 1 51  ? 25.00734  23.67949  15.63404 1.000 69.22724  ? 42   ASN A OD1   1 
ATOM   648  N  ND2   . ASN A 1 51  ? 26.17197  25.58209  15.37295 1.000 77.41198  ? 42   ASN A ND2   1 
ATOM   649  H  H     . ASN A 1 51  ? 25.34680  24.69231  19.05526 1.000 89.55735  ? 42   ASN A H     1 
ATOM   650  H  HA    . ASN A 1 51  ? 25.60927  22.48755  17.61569 1.000 87.89373  ? 42   ASN A HA    1 
ATOM   651  H  HB2   . ASN A 1 51  ? 27.01690  24.90667  17.63711 1.000 92.19523  ? 42   ASN A HB2   1 
ATOM   652  H  HB3   . ASN A 1 51  ? 27.60801  23.67402  16.82681 1.000 92.19523  ? 42   ASN A HB3   1 
ATOM   653  H  HD21  . ASN A 1 51  ? 25.69671  25.82462  14.69848 1.000 92.93760  ? 42   ASN A HD21  1 
ATOM   654  H  HD22  . ASN A 1 51  ? 26.81536  26.08224  15.64772 1.000 92.93760  ? 42   ASN A HD22  1 
ATOM   655  N  N     . TYR A 1 52  ? 27.34520  22.60169  20.20840 1.000 71.85862  ? 43   TYR A N     1 
ATOM   656  C  CA    . TYR A 1 52  ? 28.21668  21.75656  21.01689 1.000 74.86430  ? 43   TYR A CA    1 
ATOM   657  C  C     . TYR A 1 52  ? 27.57123  20.39926  21.26599 1.000 69.36567  ? 43   TYR A C     1 
ATOM   658  O  O     . TYR A 1 52  ? 28.25301  19.36803  21.25816 1.000 65.03027  ? 43   TYR A O     1 
ATOM   659  C  CB    . TYR A 1 52  ? 28.54803  22.44913  22.33763 1.000 80.79737  ? 43   TYR A CB    1 
ATOM   660  C  CG    . TYR A 1 52  ? 29.41408  23.68456  22.18704 1.000 86.67861  ? 43   TYR A CG    1 
ATOM   661  C  CD1   . TYR A 1 52  ? 30.15769  23.90477  21.03245 1.000 86.50413  ? 43   TYR A CD1   1 
ATOM   662  C  CD2   . TYR A 1 52  ? 29.48722  24.63109  23.19989 1.000 89.19729  ? 43   TYR A CD2   1 
ATOM   663  C  CE1   . TYR A 1 52  ? 30.94722  25.02880  20.89228 1.000 91.26636  ? 43   TYR A CE1   1 
ATOM   664  C  CE2   . TYR A 1 52  ? 30.27752  25.75963  23.06905 1.000 90.85457  ? 43   TYR A CE2   1 
ATOM   665  C  CZ    . TYR A 1 52  ? 31.00459  25.95283  21.91261 1.000 89.24339  ? 43   TYR A CZ    1 
ATOM   666  O  OH    . TYR A 1 52  ? 31.79236  27.07290  21.77270 1.000 93.28456  ? 43   TYR A OH    1 
ATOM   667  H  H     . TYR A 1 52  ? 26.97569  23.25203  20.63281 1.000 86.27356  ? 43   TYR A H     1 
ATOM   668  H  HA    . TYR A 1 52  ? 29.05095  21.61560  20.54253 1.000 89.88037  ? 43   TYR A HA    1 
ATOM   669  H  HB2   . TYR A 1 52  ? 27.71938  22.71998  22.76293 1.000 97.00006  ? 43   TYR A HB2   1 
ATOM   670  H  HB3   . TYR A 1 52  ? 29.02351  21.82321  22.90600 1.000 97.00006  ? 43   TYR A HB3   1 
ATOM   671  H  HD1   . TYR A 1 52  ? 30.12245  23.28308  20.34168 1.000 103.84818 ? 43   TYR A HD1   1 
ATOM   672  H  HD2   . TYR A 1 52  ? 28.99667  24.50464  23.97981 1.000 107.07996 ? 43   TYR A HD2   1 
ATOM   673  H  HE1   . TYR A 1 52  ? 31.43765  25.16145  20.11332 1.000 109.56285 ? 43   TYR A HE1   1 
ATOM   674  H  HE2   . TYR A 1 52  ? 30.31825  26.38427  23.75684 1.000 109.06871 ? 43   TYR A HE2   1 
ATOM   675  H  HH    . TYR A 1 52  ? 31.76632  27.53208  22.47560 1.000 111.98469 ? 43   TYR A HH    1 
ATOM   676  N  N     . PHE A 1 53  ? 26.25504  20.38049  21.48702 1.000 70.05138  ? 44   PHE A N     1 
ATOM   677  C  CA    . PHE A 1 53  ? 25.53948  19.11214  21.53837 1.000 64.67052  ? 44   PHE A CA    1 
ATOM   678  C  C     . PHE A 1 53  ? 25.48188  18.45407  20.16497 1.000 62.89883  ? 44   PHE A C     1 
ATOM   679  O  O     . PHE A 1 53  ? 25.46753  17.22111  20.06955 1.000 59.44494  ? 44   PHE A O     1 
ATOM   680  C  CB    . PHE A 1 53  ? 24.13118  19.32760  22.09189 1.000 66.21866  ? 44   PHE A CB    1 
ATOM   681  C  CG    . PHE A 1 53  ? 24.10457  19.71136  23.54643 1.000 65.21496  ? 44   PHE A CG    1 
ATOM   682  C  CD1   . PHE A 1 53  ? 24.41526  18.78189  24.52561 1.000 66.98216  ? 44   PHE A CD1   1 
ATOM   683  C  CD2   . PHE A 1 53  ? 23.76342  20.99595  23.93496 1.000 68.31201  ? 44   PHE A CD2   1 
ATOM   684  C  CE1   . PHE A 1 53  ? 24.39200  19.12744  25.86454 1.000 69.68246  ? 44   PHE A CE1   1 
ATOM   685  C  CE2   . PHE A 1 53  ? 23.73836  21.34782  25.27341 1.000 67.06033  ? 44   PHE A CE2   1 
ATOM   686  C  CZ    . PHE A 1 53  ? 24.05243  20.41174  26.23877 1.000 67.03896  ? 44   PHE A CZ    1 
ATOM   687  H  H     . PHE A 1 53  ? 25.76445  21.07643  21.60786 1.000 84.10487  ? 44   PHE A H     1 
ATOM   688  H  HA    . PHE A 1 53  ? 26.00357  18.50947  22.14029 1.000 77.64784  ? 44   PHE A HA    1 
ATOM   689  H  HB2   . PHE A 1 53  ? 23.70417  20.03936  21.58992 1.000 79.50561  ? 44   PHE A HB2   1 
ATOM   690  H  HB3   . PHE A 1 53  ? 23.62794  18.50421  21.99355 1.000 79.50561  ? 44   PHE A HB3   1 
ATOM   691  H  HD1   . PHE A 1 53  ? 24.64242  17.91433  24.27938 1.000 80.42181  ? 44   PHE A HD1   1 
ATOM   692  H  HD2   . PHE A 1 53  ? 23.54863  21.62967  23.28907 1.000 82.01763  ? 44   PHE A HD2   1 
ATOM   693  H  HE1   . PHE A 1 53  ? 24.60500  18.49492  26.51219 1.000 83.66216  ? 44   PHE A HE1   1 
ATOM   694  H  HE2   . PHE A 1 53  ? 23.51009  22.21430  25.52244 1.000 80.51562  ? 44   PHE A HE2   1 
ATOM   695  H  HZ    . PHE A 1 53  ? 24.03519  20.64607  27.13860 1.000 80.48997  ? 44   PHE A HZ    1 
ATOM   696  N  N     . VAL A 1 54  ? 25.44702  19.25359  19.09582 1.000 64.29970  ? 45   VAL A N     1 
ATOM   697  C  CA    . VAL A 1 54  ? 25.53757  18.69697  17.74875 1.000 64.56784  ? 45   VAL A CA    1 
ATOM   698  C  C     . VAL A 1 54  ? 26.86086  17.96528  17.56795 1.000 64.82677  ? 45   VAL A C     1 
ATOM   699  O  O     . VAL A 1 54  ? 26.91961  16.89756  16.94349 1.000 55.95605  ? 45   VAL A O     1 
ATOM   700  C  CB    . VAL A 1 54  ? 25.36612  19.81024  16.69792 1.000 65.54995  ? 45   VAL A CB    1 
ATOM   701  C  CG1   . VAL A 1 54  ? 25.71902  19.29736  15.31002 1.000 68.59517  ? 45   VAL A CG1   1 
ATOM   702  C  CG2   . VAL A 1 54  ? 23.94684  20.35123  16.71809 1.000 68.59847  ? 45   VAL A CG2   1 
ATOM   703  H  H     . VAL A 1 54  ? 25.37248  20.10987  19.12436 1.000 77.20286  ? 45   VAL A H     1 
ATOM   704  H  HA    . VAL A 1 54  ? 24.81813  18.05710  17.63103 1.000 77.52462  ? 45   VAL A HA    1 
ATOM   705  H  HB    . VAL A 1 54  ? 25.97111  20.53656  16.91554 1.000 78.70315  ? 45   VAL A HB    1 
ATOM   706  H  HG11  . VAL A 1 54  ? 25.38219  19.92099  14.64780 1.000 82.35742  ? 45   VAL A HG11  1 
ATOM   707  H  HG12  . VAL A 1 54  ? 26.68347  19.22503  15.23586 1.000 82.35742  ? 45   VAL A HG12  1 
ATOM   708  H  HG13  . VAL A 1 54  ? 25.31120  18.42662  15.18198 1.000 82.35742  ? 45   VAL A HG13  1 
ATOM   709  H  HG21  . VAL A 1 54  ? 23.87855  21.08244  16.08439 1.000 82.36139  ? 45   VAL A HG21  1 
ATOM   710  H  HG22  . VAL A 1 54  ? 23.33453  19.64078  16.47062 1.000 82.36139  ? 45   VAL A HG22  1 
ATOM   711  H  HG23  . VAL A 1 54  ? 23.74223  20.66787  17.61183 1.000 82.36139  ? 45   VAL A HG23  1 
ATOM   712  N  N     . VAL A 1 55  ? 27.94488  18.52983  18.10547 1.000 63.13744  ? 46   VAL A N     1 
ATOM   713  C  CA    . VAL A 1 55  ? 29.25445  17.90432  17.95683 1.000 64.53492  ? 46   VAL A CA    1 
ATOM   714  C  C     . VAL A 1 55  ? 29.34732  16.64751  18.81301 1.000 63.92293  ? 46   VAL A C     1 
ATOM   715  O  O     . VAL A 1 55  ? 29.96286  15.65170  18.41246 1.000 58.55150  ? 46   VAL A O     1 
ATOM   716  C  CB    . VAL A 1 55  ? 30.36668  18.90970  18.30285 1.000 70.26224  ? 46   VAL A CB    1 
ATOM   717  C  CG1   . VAL A 1 55  ? 31.70202  18.19733  18.41923 1.000 76.37883  ? 46   VAL A CG1   1 
ATOM   718  C  CG2   . VAL A 1 55  ? 30.43657  20.00246  17.24922 1.000 65.35994  ? 46   VAL A CG2   1 
ATOM   719  H  H     . VAL A 1 55  ? 27.94697  19.26374  18.55377 1.000 75.80814  ? 46   VAL A H     1 
ATOM   720  H  HA    . VAL A 1 55  ? 29.36573  17.64100  17.02991 1.000 77.48513  ? 46   VAL A HA    1 
ATOM   721  H  HB    . VAL A 1 55  ? 30.16614  19.32314  19.15710 1.000 84.35791  ? 46   VAL A HB    1 
ATOM   722  H  HG11  . VAL A 1 55  ? 32.41540  18.85184  18.35922 1.000 91.69781  ? 46   VAL A HG11  1 
ATOM   723  H  HG12  . VAL A 1 55  ? 31.74298  17.74085  19.27413 1.000 91.69781  ? 46   VAL A HG12  1 
ATOM   724  H  HG13  . VAL A 1 55  ? 31.78112  17.55468  17.69698 1.000 91.69781  ? 46   VAL A HG13  1 
ATOM   725  H  HG21  . VAL A 1 55  ? 31.04890  20.69216  17.54969 1.000 78.47514  ? 46   VAL A HG21  1 
ATOM   726  H  HG22  . VAL A 1 55  ? 30.75346  19.61861  16.41667 1.000 78.47514  ? 46   VAL A HG22  1 
ATOM   727  H  HG23  . VAL A 1 55  ? 29.55093  20.37791  17.12440 1.000 78.47514  ? 46   VAL A HG23  1 
ATOM   728  N  N     . SER A 1 56  ? 28.75238  16.67276  20.00780 1.000 62.41748  ? 47   SER A N     1 
ATOM   729  C  CA    . SER A 1 56  ? 28.69449  15.46094  20.81810 1.000 61.56057  ? 47   SER A CA    1 
ATOM   730  C  C     . SER A 1 56  ? 27.97585  14.34774  20.06833 1.000 57.55136  ? 47   SER A C     1 
ATOM   731  O  O     . SER A 1 56  ? 28.40419  13.18741  20.09425 1.000 56.38370  ? 47   SER A O     1 
ATOM   732  C  CB    . SER A 1 56  ? 27.99529  15.74790  22.14731 1.000 61.80998  ? 47   SER A CB    1 
ATOM   733  O  OG    . SER A 1 56  ? 28.04483  14.61780  23.00300 1.000 57.01672  ? 47   SER A OG    1 
ATOM   734  H  H     . SER A 1 56  ? 28.38346  17.36384  20.36264 1.000 74.94419  ? 47   SER A H     1 
ATOM   735  H  HA    . SER A 1 56  ? 29.59792  15.16764  21.01479 1.000 73.91590  ? 47   SER A HA    1 
ATOM   736  H  HB2   . SER A 1 56  ? 28.43946  16.49231  22.58260 1.000 74.21519  ? 47   SER A HB2   1 
ATOM   737  H  HB3   . SER A 1 56  ? 27.06742  15.97091  21.97344 1.000 74.21519  ? 47   SER A HB3   1 
ATOM   738  H  HG    . SER A 1 56  ? 27.59524  13.98883  22.67458 1.000 68.46328  ? 47   SER A HG    1 
ATOM   739  N  N     . LEU A 1 57  ? 26.87810  14.68664  19.39233 1.000 55.95023  ? 48   LEU A N     1 
ATOM   740  C  CA    . LEU A 1 57  ? 26.15655  13.70075  18.59626 1.000 54.85494  ? 48   LEU A CA    1 
ATOM   741  C  C     . LEU A 1 57  ? 26.99112  13.23397  17.40935 1.000 54.78733  ? 48   LEU A C     1 
ATOM   742  O  O     . LEU A 1 57  ? 27.00053  12.04162  17.08063 1.000 50.05078  ? 48   LEU A O     1 
ATOM   743  C  CB    . LEU A 1 57  ? 24.83256  14.30213  18.13009 1.000 59.53294  ? 48   LEU A CB    1 
ATOM   744  C  CG    . LEU A 1 57  ? 23.93934  13.47829  17.20913 1.000 63.86523  ? 48   LEU A CG    1 
ATOM   745  C  CD1   . LEU A 1 57  ? 23.48275  12.19621  17.88331 1.000 63.10876  ? 48   LEU A CD1   1 
ATOM   746  C  CD2   . LEU A 1 57  ? 22.74733  14.32685  16.79157 1.000 64.44415  ? 48   LEU A CD2   1 
ATOM   747  H  H     . LEU A 1 57  ? 26.53386  15.47462  19.37874 1.000 67.18349  ? 48   LEU A H     1 
ATOM   748  H  HA    . LEU A 1 57  ? 25.96279  12.92242  19.14175 1.000 65.86914  ? 48   LEU A HA    1 
ATOM   749  H  HB2   . LEU A 1 57  ? 24.30653  14.49839  18.92108 1.000 71.48274  ? 48   LEU A HB2   1 
ATOM   750  H  HB3   . LEU A 1 57  ? 25.03601  15.12292  17.65490 1.000 71.48274  ? 48   LEU A HB3   1 
ATOM   751  H  HG    . LEU A 1 57  ? 24.43781  13.21564  16.41955 1.000 76.68149  ? 48   LEU A HG    1 
ATOM   752  H  HD11  . LEU A 1 57  ? 22.91247  11.70391  17.27232 1.000 75.77373  ? 48   LEU A HD11  1 
ATOM   753  H  HD12  . LEU A 1 57  ? 24.26141  11.66419  18.11034 1.000 75.77373  ? 48   LEU A HD12  1 
ATOM   754  H  HD13  . LEU A 1 57  ? 22.98957  12.42079  18.68782 1.000 75.77373  ? 48   LEU A HD13  1 
ATOM   755  H  HD21  . LEU A 1 57  ? 22.17596  13.80339  16.20811 1.000 77.37620  ? 48   LEU A HD21  1 
ATOM   756  H  HD22  . LEU A 1 57  ? 22.25574  14.59270  17.58439 1.000 77.37620  ? 48   LEU A HD22  1 
ATOM   757  H  HD23  . LEU A 1 57  ? 23.06812  15.11279  16.32223 1.000 77.37620  ? 48   LEU A HD23  1 
ATOM   758  N  N     . ALA A 1 58  ? 27.69864  14.15780  16.75415 1.000 56.72694  ? 49   ALA A N     1 
ATOM   759  C  CA    . ALA A 1 58  ? 28.54326  13.77683  15.62657 1.000 52.44183  ? 49   ALA A CA    1 
ATOM   760  C  C     . ALA A 1 58  ? 29.66114  12.84209  16.07002 1.000 54.22342  ? 49   ALA A C     1 
ATOM   761  O  O     . ALA A 1 58  ? 30.01865  11.90269  15.34903 1.000 46.55254  ? 49   ALA A O     1 
ATOM   762  C  CB    . ALA A 1 58  ? 29.12085  15.02448  14.95812 1.000 58.35607  ? 49   ALA A CB    1 
ATOM   763  H  H     . ALA A 1 58  ? 27.70590  14.99731  16.94064 1.000 68.11554  ? 49   ALA A H     1 
ATOM   764  H  HA    . ALA A 1 58  ? 28.00063  13.30991  14.97202 1.000 62.97341  ? 49   ALA A HA    1 
ATOM   765  H  HB1   . ALA A 1 58  ? 29.67900  14.75356  14.21250 1.000 70.07050  ? 49   ALA A HB1   1 
ATOM   766  H  HB2   . ALA A 1 58  ? 28.39115  15.57916  14.64067 1.000 70.07050  ? 49   ALA A HB2   1 
ATOM   767  H  HB3   . ALA A 1 58  ? 29.65033  15.51393  15.60696 1.000 70.07050  ? 49   ALA A HB3   1 
ATOM   768  N  N     . ALA A 1 59  ? 30.22917  13.08597  17.25430 1.000 55.15239  ? 50   ALA A N     1 
ATOM   769  C  CA    . ALA A 1 59  ? 31.24593  12.18384  17.78341 1.000 54.16926  ? 50   ALA A CA    1 
ATOM   770  C  C     . ALA A 1 59  ? 30.67481  10.78999  18.00344 1.000 54.85720  ? 50   ALA A C     1 
ATOM   771  O  O     . ALA A 1 59  ? 31.33957  9.78370   17.72423 1.000 51.29138  ? 50   ALA A O     1 
ATOM   772  C  CB    . ALA A 1 59  ? 31.81373  12.74092  19.08779 1.000 60.73238  ? 50   ALA A CB    1 
ATOM   773  H  H     . ALA A 1 59  ? 30.04511  13.75615  17.76084 1.000 66.22608  ? 50   ALA A H     1 
ATOM   774  H  HA    . ALA A 1 59  ? 31.97251  12.11809  17.14414 1.000 65.04633  ? 50   ALA A HA    1 
ATOM   775  H  HB1   . ALA A 1 59  ? 32.47650  12.12262  19.43324 1.000 72.92207  ? 50   ALA A HB1   1 
ATOM   776  H  HB2   . ALA A 1 59  ? 32.22464  13.60166  18.91120 1.000 72.92207  ? 50   ALA A HB2   1 
ATOM   777  H  HB3   . ALA A 1 59  ? 31.09214  12.84394  19.72779 1.000 72.92207  ? 50   ALA A HB3   1 
ATOM   778  N  N     . ALA A 1 60  ? 29.44050  10.71122  18.50612 1.000 55.81475  ? 51   ALA A N     1 
ATOM   779  C  CA    . ALA A 1 60  ? 28.79551  9.41435   18.67574 1.000 51.84403  ? 51   ALA A CA    1 
ATOM   780  C  C     . ALA A 1 60  ? 28.68026  8.68160   17.34555 1.000 50.42938  ? 51   ALA A C     1 
ATOM   781  O  O     . ALA A 1 60  ? 28.94494  7.47607   17.26788 1.000 56.48514  ? 51   ALA A O     1 
ATOM   782  C  CB    . ALA A 1 60  ? 27.41611  9.59321   19.31014 1.000 51.35009  ? 51   ALA A CB    1 
ATOM   783  H  H     . ALA A 1 60  ? 28.96441  11.38385  18.75210 1.000 67.02092  ? 51   ALA A H     1 
ATOM   784  H  HA    . ALA A 1 60  ? 29.33316  8.87247   19.27423 1.000 62.25606  ? 51   ALA A HA    1 
ATOM   785  H  HB1   . ALA A 1 60  ? 27.00197  8.72250   19.41616 1.000 61.66333  ? 51   ALA A HB1   1 
ATOM   786  H  HB2   . ALA A 1 60  ? 27.51943  10.01800  20.17604 1.000 61.66333  ? 51   ALA A HB2   1 
ATOM   787  H  HB3   . ALA A 1 60  ? 26.87212  10.14998  18.73137 1.000 61.66333  ? 51   ALA A HB3   1 
ATOM   788  N  N     . ASP A 1 61  ? 28.29134  9.39290   16.28423 1.000 44.32777  ? 52   ASP A N     1 
ATOM   789  C  CA    . ASP A 1 61  ? 28.16984  8.75453   14.97641 1.000 54.14929  ? 52   ASP A CA    1 
ATOM   790  C  C     . ASP A 1 61  ? 29.53412  8.34355   14.42896 1.000 53.78031  ? 52   ASP A C     1 
ATOM   791  O  O     . ASP A 1 61  ? 29.67738  7.25557   13.85869 1.000 49.48983  ? 52   ASP A O     1 
ATOM   792  C  CB    . ASP A 1 61  ? 27.45840  9.69049   13.99890 1.000 49.62461  ? 52   ASP A CB    1 
ATOM   793  C  CG    . ASP A 1 61  ? 25.98209  9.86878   14.32421 1.000 51.86486  ? 52   ASP A CG    1 
ATOM   794  O  OD1   . ASP A 1 61  ? 25.36064  8.91550   14.84064 1.000 47.14651  ? 52   ASP A OD1   1 
ATOM   795  O  OD2   . ASP A 1 61  ? 25.44033  10.96297  14.05714 1.000 52.32068  ? 52   ASP A OD2   1 
ATOM   796  H  H     . ASP A 1 61  ? 28.09596  10.23033  16.29575 1.000 53.23654  ? 52   ASP A H     1 
ATOM   797  H  HA    . ASP A 1 61  ? 27.63160  7.95311   15.07092 1.000 65.02237  ? 52   ASP A HA    1 
ATOM   798  H  HB2   . ASP A 1 61  ? 27.88059  10.56314  14.03258 1.000 59.59275  ? 52   ASP A HB2   1 
ATOM   799  H  HB3   . ASP A 1 61  ? 27.52617  9.32348   13.10357 1.000 59.59275  ? 52   ASP A HB3   1 
ATOM   800  N  N     . ILE A 1 62  ? 30.54628  9.20228   14.58136 1.000 55.43196  ? 53   ILE A N     1 
ATOM   801  C  CA    . ILE A 1 62  ? 31.89962  8.82770   14.17668 1.000 57.59676  ? 53   ILE A CA    1 
ATOM   802  C  C     . ILE A 1 62  ? 32.30703  7.52674   14.85295 1.000 54.06941  ? 53   ILE A C     1 
ATOM   803  O  O     . ILE A 1 62  ? 32.89394  6.63637   14.22568 1.000 53.47628  ? 53   ILE A O     1 
ATOM   804  C  CB    . ILE A 1 62  ? 32.89067  9.96454   14.49536 1.000 59.49697  ? 53   ILE A CB    1 
ATOM   805  C  CG1   . ILE A 1 62  ? 32.61204  11.17053  13.59465 1.000 61.52931  ? 53   ILE A CG1   1 
ATOM   806  C  CG2   . ILE A 1 62  ? 34.32800  9.47996   14.32988 1.000 64.21797  ? 53   ILE A CG2   1 
ATOM   807  C  CD1   . ILE A 1 62  ? 33.34680  12.43174  13.99737 1.000 59.02430  ? 53   ILE A CD1   1 
ATOM   808  H  H     . ILE A 1 62  ? 30.47580  9.99354   14.91081 1.000 66.56157  ? 53   ILE A H     1 
ATOM   809  H  HA    . ILE A 1 62  ? 31.90862  8.68722   13.21695 1.000 69.15932  ? 53   ILE A HA    1 
ATOM   810  H  HB    . ILE A 1 62  ? 32.76826  10.23625  15.41845 1.000 71.43958  ? 53   ILE A HB    1 
ATOM   811  H  HG12  . ILE A 1 62  ? 32.88156  10.94990  12.68934 1.000 73.87839  ? 53   ILE A HG12  1 
ATOM   812  H  HG13  . ILE A 1 62  ? 31.66173  11.36331  13.62021 1.000 73.87839  ? 53   ILE A HG13  1 
ATOM   813  H  HG21  . ILE A 1 62  ? 34.92253  10.24637  14.33775 1.000 77.10478  ? 53   ILE A HG21  1 
ATOM   814  H  HG22  . ILE A 1 62  ? 34.54678  8.88407   15.06333 1.000 77.10478  ? 53   ILE A HG22  1 
ATOM   815  H  HG23  . ILE A 1 62  ? 34.40715  9.00858   13.48583 1.000 77.10478  ? 53   ILE A HG23  1 
ATOM   816  H  HD11  . ILE A 1 62  ? 33.05143  13.16321  13.43291 1.000 70.87237  ? 53   ILE A HD11  1 
ATOM   817  H  HD12  . ILE A 1 62  ? 33.14871  12.62975  14.92605 1.000 70.87237  ? 53   ILE A HD12  1 
ATOM   818  H  HD13  . ILE A 1 62  ? 34.30001  12.29140  13.88513 1.000 70.87237  ? 53   ILE A HD13  1 
ATOM   819  N  N     . LEU A 1 63  ? 31.99619  7.39253   16.14380 1.000 53.73077  ? 54   LEU A N     1 
ATOM   820  C  CA    . LEU A 1 63  ? 32.35088  6.17105   16.85770 1.000 57.22799  ? 54   LEU A CA    1 
ATOM   821  C  C     . LEU A 1 63  ? 31.50965  4.98850   16.39451 1.000 51.02106  ? 54   LEU A C     1 
ATOM   822  O  O     . LEU A 1 63  ? 31.97900  3.84611   16.43463 1.000 48.49545  ? 54   LEU A O     1 
ATOM   823  C  CB    . LEU A 1 63  ? 32.20284  6.38440   18.36392 1.000 56.87913  ? 54   LEU A CB    1 
ATOM   824  C  CG    . LEU A 1 63  ? 33.16264  7.41869   18.96234 1.000 61.14881  ? 54   LEU A CG    1 
ATOM   825  C  CD1   . LEU A 1 63  ? 32.83781  7.67425   20.42977 1.000 59.61083  ? 54   LEU A CD1   1 
ATOM   826  C  CD2   . LEU A 1 63  ? 34.61207  6.97517   18.80111 1.000 54.71732  ? 54   LEU A CD2   1 
ATOM   827  H  H     . LEU A 1 63  ? 31.58842  7.98275   16.61810 1.000 64.52014  ? 54   LEU A H     1 
ATOM   828  H  HA    . LEU A 1 63  ? 33.28063  5.95947   16.67966 1.000 68.71681  ? 54   LEU A HA    1 
ATOM   829  H  HB2   . LEU A 1 63  ? 31.29857  6.68551   18.54431 1.000 68.29817  ? 54   LEU A HB2   1 
ATOM   830  H  HB3   . LEU A 1 63  ? 32.36672  5.53963   18.81160 1.000 68.29817  ? 54   LEU A HB3   1 
ATOM   831  H  HG    . LEU A 1 63  ? 33.05344  8.25448   18.48232 1.000 73.42178  ? 54   LEU A HG    1 
ATOM   832  H  HD11  . LEU A 1 63  ? 33.44148  8.35120   20.77359 1.000 71.57622  ? 54   LEU A HD11  1 
ATOM   833  H  HD12  . LEU A 1 63  ? 31.92066  7.98183   20.50127 1.000 71.57622  ? 54   LEU A HD12  1 
ATOM   834  H  HD13  . LEU A 1 63  ? 32.94944  6.84852   20.92637 1.000 71.57622  ? 54   LEU A HD13  1 
ATOM   835  H  HD21  . LEU A 1 63  ? 35.18255  7.56686   19.31623 1.000 65.70400  ? 54   LEU A HD21  1 
ATOM   836  H  HD22  . LEU A 1 63  ? 34.70166  6.06504   19.12444 1.000 65.70400  ? 54   LEU A HD22  1 
ATOM   837  H  HD23  . LEU A 1 63  ? 34.85286  7.01794   17.86244 1.000 65.70400  ? 54   LEU A HD23  1 
ATOM   838  N  N     . VAL A 1 64  ? 30.27538  5.23532   15.95039 1.000 53.31049  ? 55   VAL A N     1 
ATOM   839  C  CA    . VAL A 1 64  ? 29.47518  4.16182   15.36394 1.000 53.42270  ? 55   VAL A CA    1 
ATOM   840  C  C     . VAL A 1 64  ? 30.21972  3.53801   14.19021 1.000 50.56875  ? 55   VAL A C     1 
ATOM   841  O  O     . VAL A 1 64  ? 30.28661  2.31021   14.05169 1.000 55.33139  ? 55   VAL A O     1 
ATOM   842  C  CB    . VAL A 1 64  ? 28.09410  4.68964   14.93329 1.000 50.70199  ? 55   VAL A CB    1 
ATOM   843  C  CG1   . VAL A 1 64  ? 27.41749  3.70109   13.99922 1.000 42.83502  ? 55   VAL A CG1   1 
ATOM   844  C  CG2   . VAL A 1 64  ? 27.21509  4.95328   16.14848 1.000 49.49749  ? 55   VAL A CG2   1 
ATOM   845  H  H     . VAL A 1 64  ? 29.88581  6.00157   15.97679 1.000 64.01581  ? 55   VAL A H     1 
ATOM   846  H  HA    . VAL A 1 64  ? 29.33661  3.47714   16.03693 1.000 64.15046  ? 55   VAL A HA    1 
ATOM   847  H  HB    . VAL A 1 64  ? 28.21599  5.52755   14.46004 1.000 60.88561  ? 55   VAL A HB    1 
ATOM   848  H  HG11  . VAL A 1 64  ? 26.46970  3.90333   13.95815 1.000 51.44524  ? 55   VAL A HG11  1 
ATOM   849  H  HG12  . VAL A 1 64  ? 27.81124  3.78057   13.11631 1.000 51.44524  ? 55   VAL A HG12  1 
ATOM   850  H  HG13  . VAL A 1 64  ? 27.54955  2.80282   14.34066 1.000 51.44524  ? 55   VAL A HG13  1 
ATOM   851  H  HG21  . VAL A 1 64  ? 26.36513  5.31393   15.85116 1.000 59.44020  ? 55   VAL A HG21  1 
ATOM   852  H  HG22  . VAL A 1 64  ? 27.07281  4.11893   16.62231 1.000 59.44020  ? 55   VAL A HG22  1 
ATOM   853  H  HG23  . VAL A 1 64  ? 27.66046  5.59100   16.72801 1.000 59.44020  ? 55   VAL A HG23  1 
ATOM   854  N  N     . GLY A 1 65  ? 30.79392  4.37850   13.32804 1.000 51.42865  ? 56   GLY A N     1 
ATOM   855  C  CA    . GLY A 1 65  ? 31.50886  3.86124   12.17412 1.000 53.30838  ? 56   GLY A CA    1 
ATOM   856  C  C     . GLY A 1 65  ? 32.83942  3.22908   12.53677 1.000 54.75340  ? 56   GLY A C     1 
ATOM   857  O  O     . GLY A 1 65  ? 33.21837  2.19639   11.97668 1.000 52.29463  ? 56   GLY A O     1 
ATOM   858  H  H     . GLY A 1 65  ? 30.78217  5.23614   13.39068 1.000 61.75760  ? 56   GLY A H     1 
ATOM   859  H  HA2   . GLY A 1 65  ? 30.96329  3.18945   11.73601 1.000 64.01327  ? 56   GLY A HA2   1 
ATOM   860  H  HA3   . GLY A 1 65  ? 31.67707  4.58628   11.55209 1.000 64.01327  ? 56   GLY A HA3   1 
ATOM   861  N  N     . VAL A 1 66  ? 33.56497  3.83208   13.47885 1.000 53.43212  ? 57   VAL A N     1 
ATOM   862  C  CA    . VAL A 1 66  ? 34.90739  3.34943   13.78063 1.000 53.48987  ? 57   VAL A CA    1 
ATOM   863  C  C     . VAL A 1 66  ? 34.86916  2.10666   14.66601 1.000 56.27285  ? 57   VAL A C     1 
ATOM   864  O  O     . VAL A 1 66  ? 35.73319  1.23130   14.54188 1.000 49.99873  ? 57   VAL A O     1 
ATOM   865  C  CB    . VAL A 1 66  ? 35.74111  4.46938   14.42858 1.000 53.82433  ? 57   VAL A CB    1 
ATOM   866  C  CG1   . VAL A 1 66  ? 37.08833  3.93146   14.89949 1.000 59.83720  ? 57   VAL A CG1   1 
ATOM   867  C  CG2   . VAL A 1 66  ? 35.93945  5.61996   13.44940 1.000 59.61724  ? 57   VAL A CG2   1 
ATOM   868  H  H     . VAL A 1 66  ? 33.30804  4.50677   13.94617 1.000 64.16176  ? 57   VAL A H     1 
ATOM   869  H  HA    . VAL A 1 66  ? 35.33191  3.09792   12.94552 1.000 64.23106  ? 57   VAL A HA    1 
ATOM   870  H  HB    . VAL A 1 66  ? 35.26305  4.80659   15.20231 1.000 64.63241  ? 57   VAL A HB    1 
ATOM   871  H  HG11  . VAL A 1 66  ? 37.67644  4.67822   15.09282 1.000 71.84786  ? 57   VAL A HG11  1 
ATOM   872  H  HG12  . VAL A 1 66  ? 36.95398  3.40036   15.69999 1.000 71.84786  ? 57   VAL A HG12  1 
ATOM   873  H  HG13  . VAL A 1 66  ? 37.47144  3.38164   14.19819 1.000 71.84786  ? 57   VAL A HG13  1 
ATOM   874  H  HG21  . VAL A 1 66  ? 36.45007  6.32053   13.88457 1.000 71.58390  ? 57   VAL A HG21  1 
ATOM   875  H  HG22  . VAL A 1 66  ? 36.42022  5.29415   12.67249 1.000 71.58390  ? 57   VAL A HG22  1 
ATOM   876  H  HG23  . VAL A 1 66  ? 35.07137  5.96058   13.18235 1.000 71.58390  ? 57   VAL A HG23  1 
ATOM   877  N  N     . LEU A 1 67  ? 33.88442  1.99553   15.55690 1.000 52.68485  ? 58   LEU A N     1 
ATOM   878  C  CA    . LEU A 1 67  ? 33.85126  0.92066   16.54152 1.000 51.65505  ? 58   LEU A CA    1 
ATOM   879  C  C     . LEU A 1 67  ? 32.57873  0.09355   16.47795 1.000 54.19394  ? 58   LEU A C     1 
ATOM   880  O  O     . LEU A 1 67  ? 32.65176  -1.14006  16.41635 1.000 52.41013  ? 58   LEU A O     1 
ATOM   881  C  CB    . LEU A 1 67  ? 34.01771  1.50411   17.95499 1.000 55.90128  ? 58   LEU A CB    1 
ATOM   882  C  CG    . LEU A 1 67  ? 35.43118  1.94314   18.34293 1.000 55.98248  ? 58   LEU A CG    1 
ATOM   883  C  CD1   . LEU A 1 67  ? 35.38642  2.86524   19.55014 1.000 56.93285  ? 58   LEU A CD1   1 
ATOM   884  C  CD2   . LEU A 1 67  ? 36.30904  0.73200   18.62659 1.000 58.84647  ? 58   LEU A CD2   1 
ATOM   885  H  H     . LEU A 1 67  ? 33.21849  2.53715   15.60968 1.000 63.26503  ? 58   LEU A H     1 
ATOM   886  H  HA    . LEU A 1 67  ? 34.59506  0.32379   16.36429 1.000 62.02928  ? 58   LEU A HA    1 
ATOM   887  H  HB2   . LEU A 1 67  ? 33.44543  2.28383   18.02867 1.000 67.12475  ? 58   LEU A HB2   1 
ATOM   888  H  HB3   . LEU A 1 67  ? 33.74213  0.82871   18.59437 1.000 67.12475  ? 58   LEU A HB3   1 
ATOM   889  H  HG    . LEU A 1 67  ? 35.82524  2.43167   17.60337 1.000 67.22220  ? 58   LEU A HG    1 
ATOM   890  H  HD11  . LEU A 1 67  ? 36.29387  3.07431   19.82166 1.000 68.36263  ? 58   LEU A HD11  1 
ATOM   891  H  HD12  . LEU A 1 67  ? 34.91760  3.67932   19.30851 1.000 68.36263  ? 58   LEU A HD12  1 
ATOM   892  H  HD13  . LEU A 1 67  ? 34.91989  2.41695   20.27283 1.000 68.36263  ? 58   LEU A HD13  1 
ATOM   893  H  HD21  . LEU A 1 67  ? 37.18857  1.03650   18.89974 1.000 70.65898  ? 58   LEU A HD21  1 
ATOM   894  H  HD22  . LEU A 1 67  ? 35.90510  0.20844   19.33626 1.000 70.65898  ? 58   LEU A HD22  1 
ATOM   895  H  HD23  . LEU A 1 67  ? 36.37972  0.19740   17.82030 1.000 70.65898  ? 58   LEU A HD23  1 
ATOM   896  N  N     . ALA A 1 68  ? 31.40825  0.73510   16.48393 1.000 49.34025  ? 59   ALA A N     1 
ATOM   897  C  CA    . ALA A 1 68  ? 30.16355  -0.01732  16.59914 1.000 53.69417  ? 59   ALA A CA    1 
ATOM   898  C  C     . ALA A 1 68  ? 29.94982  -0.92956  15.39647 1.000 52.85770  ? 59   ALA A C     1 
ATOM   899  O  O     . ALA A 1 68  ? 29.52709  -2.08168  15.55025 1.000 49.27910  ? 59   ALA A O     1 
ATOM   900  C  CB    . ALA A 1 68  ? 28.98378  0.94033   16.76333 1.000 49.75524  ? 59   ALA A CB    1 
ATOM   901  H  H     . ALA A 1 68  ? 31.31113  1.58748   16.42378 1.000 59.25152  ? 59   ALA A H     1 
ATOM   902  H  HA    . ALA A 1 68  ? 30.21123  -0.57503  17.39135 1.000 64.47623  ? 59   ALA A HA    1 
ATOM   903  H  HB1   . ALA A 1 68  ? 28.19329  0.43006   16.99923 1.000 59.74950  ? 59   ALA A HB1   1 
ATOM   904  H  HB2   . ALA A 1 68  ? 29.18885  1.57645   17.46633 1.000 59.74950  ? 59   ALA A HB2   1 
ATOM   905  H  HB3   . ALA A 1 68  ? 28.83788  1.40813   15.92620 1.000 59.74950  ? 59   ALA A HB3   1 
ATOM   906  N  N     . ILE A 1 69  ? 30.24068  -0.44111  14.19535 1.000 50.60899  ? 60   ILE A N     1 
ATOM   907  C  CA    . ILE A 1 69  ? 29.99797  -1.21393  12.97928 1.000 53.02589  ? 60   ILE A CA    1 
ATOM   908  C  C     . ILE A 1 69  ? 31.01451  -2.34729  12.89046 1.000 53.24044  ? 60   ILE A C     1 
ATOM   909  O  O     . ILE A 1 69  ? 30.63728  -3.48256  12.56332 1.000 49.28922  ? 60   ILE A O     1 
ATOM   910  C  CB    . ILE A 1 69  ? 30.02987  -0.31544  11.73146 1.000 53.17016  ? 60   ILE A CB    1 
ATOM   911  C  CG1   . ILE A 1 69  ? 28.70873  0.45657   11.62814 1.000 50.48456  ? 60   ILE A CG1   1 
ATOM   912  C  CG2   . ILE A 1 69  ? 30.29304  -1.14928  10.48444 1.000 54.03137  ? 60   ILE A CG2   1 
ATOM   913  C  CD1   . ILE A 1 69  ? 28.63997  1.43718   10.48679 1.000 52.59499  ? 60   ILE A CD1   1 
ATOM   914  H  H     . ILE A 1 69  ? 30.58010  0.33685   14.05690 1.000 60.77400  ? 60   ILE A H     1 
ATOM   915  H  HA    . ILE A 1 69  ? 29.11728  -1.61691  13.03316 1.000 63.67429  ? 60   ILE A HA    1 
ATOM   916  H  HB    . ILE A 1 69  ? 30.75383  0.32524   11.81084 1.000 63.84741  ? 60   ILE A HB    1 
ATOM   917  H  HG12  . ILE A 1 69  ? 27.98764  -0.18118  11.50898 1.000 60.62468  ? 60   ILE A HG12  1 
ATOM   918  H  HG13  . ILE A 1 69  ? 28.57816  0.95528   12.44981 1.000 60.62468  ? 60   ILE A HG13  1 
ATOM   919  H  HG21  . ILE A 1 69  ? 30.07175  -0.62309  9.70019  1.000 64.88086  ? 60   ILE A HG21  1 
ATOM   920  H  HG22  . ILE A 1 69  ? 31.23050  -1.39746  10.46253 1.000 64.88086  ? 60   ILE A HG22  1 
ATOM   921  H  HG23  . ILE A 1 69  ? 29.74057  -1.94600  10.51489 1.000 64.88086  ? 60   ILE A HG23  1 
ATOM   922  H  HD11  . ILE A 1 69  ? 27.88129  2.02630   10.62187 1.000 63.15720  ? 60   ILE A HD11  1 
ATOM   923  H  HD12  . ILE A 1 69  ? 29.46041  1.95418   10.46477 1.000 63.15720  ? 60   ILE A HD12  1 
ATOM   924  H  HD13  . ILE A 1 69  ? 28.53496  0.94782   9.65589  1.000 63.15720  ? 60   ILE A HD13  1 
ATOM   925  N  N     . PRO A 1 70  ? 32.30279  -2.10084  13.14763 1.000 49.13369  ? 61   PRO A N     1 
ATOM   926  C  CA    . PRO A 1 70  ? 33.23259  -3.23634  13.27206 1.000 55.97989  ? 61   PRO A CA    1 
ATOM   927  C  C     . PRO A 1 70  ? 32.81593  -4.23631  14.33701 1.000 53.61242  ? 61   PRO A C     1 
ATOM   928  O  O     . PRO A 1 70  ? 32.90407  -5.44841  14.10713 1.000 49.43266  ? 61   PRO A O     1 
ATOM   929  C  CB    . PRO A 1 70  ? 34.56507  -2.55422  13.60932 1.000 55.83870  ? 61   PRO A CB    1 
ATOM   930  C  CG    . PRO A 1 70  ? 34.46920  -1.23605  12.94558 1.000 53.80902  ? 61   PRO A CG    1 
ATOM   931  C  CD    . PRO A 1 70  ? 33.02037  -0.81647  13.05799 1.000 50.46903  ? 61   PRO A CD    1 
ATOM   932  H  HA    . PRO A 1 70  ? 33.31432  -3.69408  12.42077 1.000 67.21909  ? 61   PRO A HA    1 
ATOM   933  H  HB2   . PRO A 1 70  ? 34.65738  -2.45745  14.57006 1.000 67.04965  ? 61   PRO A HB2   1 
ATOM   934  H  HB3   . PRO A 1 70  ? 35.30486  -3.07230  13.25547 1.000 67.04965  ? 61   PRO A HB3   1 
ATOM   935  H  HG2   . PRO A 1 70  ? 35.04630  -0.60044  13.39709 1.000 64.61404  ? 61   PRO A HG2   1 
ATOM   936  H  HG3   . PRO A 1 70  ? 34.73096  -1.31916  12.01527 1.000 64.61404  ? 61   PRO A HG3   1 
ATOM   937  H  HD2   . PRO A 1 70  ? 32.87594  -0.28371  13.85561 1.000 60.60605  ? 61   PRO A HD2   1 
ATOM   938  H  HD3   . PRO A 1 70  ? 32.74267  -0.31975  12.27246 1.000 60.60605  ? 61   PRO A HD3   1 
ATOM   939  N  N     . PHE A 1 71  ? 32.36450  -3.76448  15.50270 1.000 49.20096  ? 62   PHE A N     1 
ATOM   940  C  CA    . PHE A 1 71  ? 31.86277  -4.68390  16.51807 1.000 52.85217  ? 62   PHE A CA    1 
ATOM   941  C  C     . PHE A 1 71  ? 30.68146  -5.48988  15.98466 1.000 50.00190  ? 62   PHE A C     1 
ATOM   942  O  O     . PHE A 1 71  ? 30.60162  -6.70581  16.19833 1.000 47.66886  ? 62   PHE A O     1 
ATOM   943  C  CB    . PHE A 1 71  ? 31.45697  -3.91820  17.78139 1.000 49.31648  ? 62   PHE A CB    1 
ATOM   944  C  CG    . PHE A 1 71  ? 32.61865  -3.36861  18.58295 1.000 55.34602  ? 62   PHE A CG    1 
ATOM   945  C  CD1   . PHE A 1 71  ? 33.93512  -3.64224  18.23771 1.000 57.67597  ? 62   PHE A CD1   1 
ATOM   946  C  CD2   . PHE A 1 71  ? 32.37998  -2.57708  19.69816 1.000 55.85313  ? 62   PHE A CD2   1 
ATOM   947  C  CE1   . PHE A 1 71  ? 34.98514  -3.13048  18.98702 1.000 58.82517  ? 62   PHE A CE1   1 
ATOM   948  C  CE2   . PHE A 1 71  ? 33.42599  -2.06638  20.44800 1.000 53.56606  ? 62   PHE A CE2   1 
ATOM   949  C  CZ    . PHE A 1 71  ? 34.72768  -2.34435  20.09224 1.000 58.54883  ? 62   PHE A CZ    1 
ATOM   950  H  H     . PHE A 1 71  ? 32.33947  -2.93369  15.72351 1.000 59.08437  ? 62   PHE A H     1 
ATOM   951  H  HA    . PHE A 1 71  ? 32.57353  -5.29832  16.75932 1.000 63.46582  ? 62   PHE A HA    1 
ATOM   952  H  HB2   . PHE A 1 71  ? 30.89902  -3.16822  17.52233 1.000 59.22299  ? 62   PHE A HB2   1 
ATOM   953  H  HB3   . PHE A 1 71  ? 30.95965  -4.51754  18.35963 1.000 59.22299  ? 62   PHE A HB3   1 
ATOM   954  H  HD1   . PHE A 1 71  ? 34.11530  -4.17414  17.49641 1.000 69.25439  ? 62   PHE A HD1   1 
ATOM   955  H  HD2   . PHE A 1 71  ? 31.50388  -2.38688  19.94549 1.000 67.06698  ? 62   PHE A HD2   1 
ATOM   956  H  HE1   . PHE A 1 71  ? 35.86325  -3.31734  18.74434 1.000 70.63343  ? 62   PHE A HE1   1 
ATOM   957  H  HE2   . PHE A 1 71  ? 33.25000  -1.53600  21.19138 1.000 64.32248  ? 62   PHE A HE2   1 
ATOM   958  H  HZ    . PHE A 1 71  ? 35.43135  -2.00314  20.59554 1.000 70.30181  ? 62   PHE A HZ    1 
ATOM   959  N  N     . ALA A 1 72  ? 29.75618  -4.82927  15.28109 1.000 46.93129  ? 63   ALA A N     1 
ATOM   960  C  CA    . ALA A 1 72  ? 28.59239  -5.52828  14.74027 1.000 49.30511  ? 63   ALA A CA    1 
ATOM   961  C  C     . ALA A 1 72  ? 29.01184  -6.61236  13.75435 1.000 51.96866  ? 63   ALA A C     1 
ATOM   962  O  O     . ALA A 1 72  ? 28.50693  -7.74057  13.79862 1.000 52.39356  ? 63   ALA A O     1 
ATOM   963  C  CB    . ALA A 1 72  ? 27.64820  -4.53128  14.06696 1.000 48.36322  ? 63   ALA A CB    1 
ATOM   964  H  H     . ALA A 1 72  ? 29.78002  -3.98760  15.10607 1.000 56.36077  ? 63   ALA A H     1 
ATOM   965  H  HA    . ALA A 1 72  ? 28.11656  -5.95110  15.47220 1.000 59.20934  ? 63   ALA A HA    1 
ATOM   966  H  HB1   . ALA A 1 72  ? 26.87586  -5.00873  13.72574 1.000 58.07908  ? 63   ALA A HB1   1 
ATOM   967  H  HB2   . ALA A 1 72  ? 27.36723  -3.87170  14.72035 1.000 58.07908  ? 63   ALA A HB2   1 
ATOM   968  H  HB3   . ALA A 1 72  ? 28.11660  -4.09578  13.33769 1.000 58.07908  ? 63   ALA A HB3   1 
ATOM   969  N  N     . ILE A 1 73  ? 29.92409  -6.27648  12.83883 1.000 50.32126  ? 64   ILE A N     1 
ATOM   970  C  CA    . ILE A 1 73  ? 30.46711  -7.26976  11.91304 1.000 53.85351  ? 64   ILE A CA    1 
ATOM   971  C  C     . ILE A 1 73  ? 31.04153  -8.44687  12.68929 1.000 54.69037  ? 64   ILE A C     1 
ATOM   972  O  O     . ILE A 1 73  ? 30.77508  -9.61376  12.37897 1.000 56.32139  ? 64   ILE A O     1 
ATOM   973  C  CB    . ILE A 1 73  ? 31.52713  -6.61885  11.00054 1.000 56.74013  ? 64   ILE A CB    1 
ATOM   974  C  CG1   . ILE A 1 73  ? 30.84965  -5.60580  10.07057 1.000 58.59609  ? 64   ILE A CG1   1 
ATOM   975  C  CG2   . ILE A 1 73  ? 32.33568  -7.68488  10.22947 1.000 59.29979  ? 64   ILE A CG2   1 
ATOM   976  C  CD1   . ILE A 1 73  ? 31.79057  -4.56765  9.49399  1.000 60.23822  ? 64   ILE A CD1   1 
ATOM   977  H  H     . ILE A 1 73  ? 30.24300  -5.48471  12.73400 1.000 60.42873  ? 64   ILE A H     1 
ATOM   978  H  HA    . ILE A 1 73  ? 29.75064  -7.60372  11.35085 1.000 64.66743  ? 64   ILE A HA    1 
ATOM   979  H  HB    . ILE A 1 73  ? 32.16771  -6.13962  11.54908 1.000 68.13137  ? 64   ILE A HB    1 
ATOM   980  H  HG12  . ILE A 1 73  ? 30.44965  -6.08516  9.32820  1.000 70.35852  ? 64   ILE A HG12  1 
ATOM   981  H  HG13  . ILE A 1 73  ? 30.16371  -5.13610  10.57035 1.000 70.35852  ? 64   ILE A HG13  1 
ATOM   982  H  HG21  . ILE A 1 73  ? 32.93401  -7.23983  9.60912  1.000 71.20296  ? 64   ILE A HG21  1 
ATOM   983  H  HG22  . ILE A 1 73  ? 32.84786  -8.21184  10.86263 1.000 71.20296  ? 64   ILE A HG22  1 
ATOM   984  H  HG23  . ILE A 1 73  ? 31.72123  -8.25697  9.74362  1.000 71.20296  ? 64   ILE A HG23  1 
ATOM   985  H  HD11  . ILE A 1 73  ? 31.29207  -3.98474  8.90018  1.000 72.32908  ? 64   ILE A HD11  1 
ATOM   986  H  HD12  . ILE A 1 73  ? 32.17376  -4.05087  10.21994 1.000 72.32908  ? 64   ILE A HD12  1 
ATOM   987  H  HD13  . ILE A 1 73  ? 32.49426  -5.01819  9.00130  1.000 72.32908  ? 64   ILE A HD13  1 
ATOM   988  N  N     . THR A 1 74  ? 31.82872  -8.15103  13.72473 1.000 51.96028  ? 65   THR A N     1 
ATOM   989  C  CA    . THR A 1 74  ? 32.47771  -9.20404  14.49745 1.000 56.20570  ? 65   THR A CA    1 
ATOM   990  C  C     . THR A 1 74  ? 31.45107  -10.13034 15.13816 1.000 58.65705  ? 65   THR A C     1 
ATOM   991  O  O     . THR A 1 74  ? 31.51444  -11.35476 14.97737 1.000 58.38709  ? 65   THR A O     1 
ATOM   992  C  CB    . THR A 1 74  ? 33.37510  -8.58036  15.56772 1.000 59.73694  ? 65   THR A CB    1 
ATOM   993  O  OG1   . THR A 1 74  ? 34.16381  -7.53560  14.98537 1.000 59.56646  ? 65   THR A OG1   1 
ATOM   994  C  CG2   . THR A 1 74  ? 34.30103  -9.62247  16.16662 1.000 72.33669  ? 65   THR A CG2   1 
ATOM   995  H  H     . THR A 1 74  ? 32.00115  -7.35378  13.99724 1.000 62.39555  ? 65   THR A H     1 
ATOM   996  H  HA    . THR A 1 74  ? 33.03063  -9.73377  13.90199 1.000 67.49005  ? 65   THR A HA    1 
ATOM   997  H  HB    . THR A 1 74  ? 32.82120  -8.21694  16.27625 1.000 71.72755  ? 65   THR A HB    1 
ATOM   998  H  HG1   . THR A 1 74  ? 34.41848  -7.00153  15.58161 1.000 71.52296  ? 65   THR A HG1   1 
ATOM   999  H  HG21  . THR A 1 74  ? 34.97040  -9.19203  16.72121 1.000 86.84725  ? 65   THR A HG21  1 
ATOM   1000 H  HG22  . THR A 1 74  ? 33.79302  -10.24378 16.71141 1.000 86.84725  ? 65   THR A HG22  1 
ATOM   1001 H  HG23  . THR A 1 74  ? 34.74707  -10.11521 15.46011 1.000 86.84725  ? 65   THR A HG23  1 
ATOM   1002 N  N     . ILE A 1 75  ? 30.49194  -9.56174  15.87280 1.000 60.45887  ? 66   ILE A N     1 
ATOM   1003 C  CA    . ILE A 1 75  ? 29.52901  -10.37711 16.60336 1.000 58.91922  ? 66   ILE A CA    1 
ATOM   1004 C  C     . ILE A 1 75  ? 28.56780  -11.11518 15.68574 1.000 59.39706  ? 66   ILE A C     1 
ATOM   1005 O  O     . ILE A 1 75  ? 27.87450  -12.03182 16.14208 1.000 58.81891  ? 66   ILE A O     1 
ATOM   1006 C  CB    . ILE A 1 75  ? 28.74865  -9.50154  17.60604 1.000 59.08754  ? 66   ILE A CB    1 
ATOM   1007 C  CG1   . ILE A 1 75  ? 28.05593  -10.38129 18.64770 1.000 63.26287  ? 66   ILE A CG1   1 
ATOM   1008 C  CG2   . ILE A 1 75  ? 27.72515  -8.63959  16.88736 1.000 55.67173  ? 66   ILE A CG2   1 
ATOM   1009 C  CD1   . ILE A 1 75  ? 27.51154  -9.61491  19.83095 1.000 58.72124  ? 66   ILE A CD1   1 
ATOM   1010 H  H     . ILE A 1 75  ? 30.38105  -8.71357  15.96169 1.000 72.59386  ? 66   ILE A H     1 
ATOM   1011 H  HA    . ILE A 1 75  ? 30.01530  -11.04962 17.10550 1.000 70.74628  ? 66   ILE A HA    1 
ATOM   1012 H  HB    . ILE A 1 75  ? 29.38188  -8.91912  18.05404 1.000 70.94827  ? 66   ILE A HB    1 
ATOM   1013 H  HG12  . ILE A 1 75  ? 27.31254  -10.83855 18.22439 1.000 75.95866  ? 66   ILE A HG12  1 
ATOM   1014 H  HG13  . ILE A 1 75  ? 28.69557  -11.02849 18.98371 1.000 75.95866  ? 66   ILE A HG13  1 
ATOM   1015 H  HG21  . ILE A 1 75  ? 27.43901  -7.92786  17.48105 1.000 66.84930  ? 66   ILE A HG21  1 
ATOM   1016 H  HG22  . ILE A 1 75  ? 28.13243  -8.26292  16.09166 1.000 66.84930  ? 66   ILE A HG22  1 
ATOM   1017 H  HG23  . ILE A 1 75  ? 26.96559  -9.19034  16.64110 1.000 66.84930  ? 66   ILE A HG23  1 
ATOM   1018 H  HD11  . ILE A 1 75  ? 27.22636  -10.24492 20.51114 1.000 70.50871  ? 66   ILE A HD11  1 
ATOM   1019 H  HD12  . ILE A 1 75  ? 28.20942  -9.04085  20.18355 1.000 70.50871  ? 66   ILE A HD12  1 
ATOM   1020 H  HD13  . ILE A 1 75  ? 26.75757  -9.07849  19.53996 1.000 70.50871  ? 66   ILE A HD13  1 
ATOM   1021 N  N     . SER A 1 76  ? 28.50886  -10.74832 14.40254 1.000 56.20656  ? 67   SER A N     1 
ATOM   1022 C  CA    . SER A 1 76  ? 27.66873  -11.48008 13.46173 1.000 60.21948  ? 67   SER A CA    1 
ATOM   1023 C  C     . SER A 1 76  ? 28.26417  -12.83270 13.09319 1.000 62.53641  ? 67   SER A C     1 
ATOM   1024 O  O     . SER A 1 76  ? 27.53190  -13.71577 12.63387 1.000 57.63288  ? 67   SER A O     1 
ATOM   1025 C  CB    . SER A 1 76  ? 27.45423  -10.65942 12.18938 1.000 59.92520  ? 67   SER A CB    1 
ATOM   1026 O  OG    . SER A 1 76  ? 28.63631  -10.61957 11.40760 1.000 58.36873  ? 67   SER A OG    1 
ATOM   1027 H  H     . SER A 1 76  ? 28.94050  -10.08838 14.05935 1.000 67.49109  ? 67   SER A H     1 
ATOM   1028 H  HA    . SER A 1 76  ? 26.80363  -11.62674 13.87524 1.000 72.30660  ? 67   SER A HA    1 
ATOM   1029 H  HB2   . SER A 1 76  ? 26.74456  -11.06581 11.66775 1.000 71.95346  ? 67   SER A HB2   1 
ATOM   1030 H  HB3   . SER A 1 76  ? 27.20820  -9.75404  12.43567 1.000 71.95346  ? 67   SER A HB3   1 
ATOM   1031 H  HG    . SER A 1 76  ? 29.26929  -10.30266 11.85983 1.000 70.08569  ? 67   SER A HG    1 
ATOM   1032 N  N     . THR A 1 77  ? 29.57367  -13.01082 13.28002 1.000 63.73117  ? 68   THR A N     1 
ATOM   1033 C  CA    . THR A 1 77  ? 30.21829  -14.26859 12.92699 1.000 63.81471  ? 68   THR A CA    1 
ATOM   1034 C  C     . THR A 1 77  ? 30.00205  -15.34360 13.98470 1.000 63.96982  ? 68   THR A C     1 
ATOM   1035 O  O     . THR A 1 77  ? 30.04994  -16.53663 13.66571 1.000 72.96952  ? 68   THR A O     1 
ATOM   1036 C  CB    . THR A 1 77  ? 31.71983  -14.05247 12.72335 1.000 67.92300  ? 68   THR A CB    1 
ATOM   1037 O  OG1   . THR A 1 77  ? 32.31892  -13.64733 13.96148 1.000 70.33516  ? 68   THR A OG1   1 
ATOM   1038 C  CG2   . THR A 1 77  ? 31.97485  -12.98362 11.66926 1.000 61.64956  ? 68   THR A CG2   1 
ATOM   1039 H  H     . THR A 1 77  ? 30.10585  -12.42026 13.60808 1.000 76.52062  ? 68   THR A H     1 
ATOM   1040 H  HA    . THR A 1 77  ? 29.83697  -14.58207 12.09199 1.000 76.62087  ? 68   THR A HA    1 
ATOM   1041 H  HB    . THR A 1 77  ? 32.12425  -14.88055 12.42066 1.000 81.55081  ? 68   THR A HB    1 
ATOM   1042 H  HG1   . THR A 1 77  ? 33.15089  -13.57775 13.86887 1.000 84.44541  ? 68   THR A HG1   1 
ATOM   1043 H  HG21  . THR A 1 77  ? 32.92878  -12.87468 11.53126 1.000 74.02269  ? 68   THR A HG21  1 
ATOM   1044 H  HG22  . THR A 1 77  ? 31.56264  -13.24065 10.82966 1.000 74.02269  ? 68   THR A HG22  1 
ATOM   1045 H  HG23  . THR A 1 77  ? 31.59980  -12.13689 11.95786 1.000 74.02269  ? 68   THR A HG23  1 
ATOM   1046 N  N     . GLY A 1 78  ? 29.76885  -14.95174 15.23444 1.000 62.15128  ? 69   GLY A N     1 
ATOM   1047 C  CA    . GLY A 1 78  ? 29.63336  -15.92316 16.30096 1.000 66.26921  ? 69   GLY A CA    1 
ATOM   1048 C  C     . GLY A 1 78  ? 30.94795  -16.46769 16.80703 1.000 69.47544  ? 69   GLY A C     1 
ATOM   1049 O  O     . GLY A 1 78  ? 30.98593  -17.57951 17.34316 1.000 74.52368  ? 69   GLY A O     1 
ATOM   1050 H  H     . GLY A 1 78  ? 29.68618  -14.13308 15.48455 1.000 74.62475  ? 69   GLY A H     1 
ATOM   1051 H  HA2   . GLY A 1 78  ? 29.17411  -15.50779 17.04759 1.000 79.56626  ? 69   GLY A HA2   1 
ATOM   1052 H  HA3   . GLY A 1 78  ? 29.10367  -16.66980 15.98025 1.000 79.56626  ? 69   GLY A HA3   1 
ATOM   1053 N  N     . PHE A 1 79  ? 32.03092  -15.70838 16.65897 1.000 70.51397  ? 70   PHE A N     1 
ATOM   1054 C  CA    . PHE A 1 79  ? 33.35174  -16.19294 17.03294 1.000 77.15595  ? 70   PHE A CA    1 
ATOM   1055 C  C     . PHE A 1 79  ? 33.41096  -16.52520 18.51976 1.000 76.83418  ? 70   PHE A C     1 
ATOM   1056 O  O     . PHE A 1 79  ? 32.72094  -15.92259 19.34630 1.000 75.39757  ? 70   PHE A O     1 
ATOM   1057 C  CB    . PHE A 1 79  ? 34.41318  -15.14537 16.68928 1.000 78.21845  ? 70   PHE A CB    1 
ATOM   1058 C  CG    . PHE A 1 79  ? 34.46641  -13.99280 17.65501 1.000 76.40558  ? 70   PHE A CG    1 
ATOM   1059 C  CD1   . PHE A 1 79  ? 33.37837  -13.15045 17.81504 1.000 70.96649  ? 70   PHE A CD1   1 
ATOM   1060 C  CD2   . PHE A 1 79  ? 35.61122  -13.74664 18.39542 1.000 76.89778  ? 70   PHE A CD2   1 
ATOM   1061 C  CE1   . PHE A 1 79  ? 33.42850  -12.09233 18.70246 1.000 73.75815  ? 70   PHE A CE1   1 
ATOM   1062 C  CE2   . PHE A 1 79  ? 35.66827  -12.68811 19.28038 1.000 71.99152  ? 70   PHE A CE2   1 
ATOM   1063 C  CZ    . PHE A 1 79  ? 34.57580  -11.86079 19.43544 1.000 76.77415  ? 70   PHE A CZ    1 
ATOM   1064 H  H     . PHE A 1 79  ? 32.02621  -14.90824 16.34376 1.000 84.65998  ? 70   PHE A H     1 
ATOM   1065 H  HA    . PHE A 1 79  ? 33.54658  -17.00378 16.53748 1.000 92.63036  ? 70   PHE A HA    1 
ATOM   1066 H  HB2   . PHE A 1 79  ? 35.28410  -15.57246 16.69053 1.000 93.90535  ? 70   PHE A HB2   1 
ATOM   1067 H  HB3   . PHE A 1 79  ? 34.22164  -14.78502 15.80931 1.000 93.90535  ? 70   PHE A HB3   1 
ATOM   1068 H  HD1   . PHE A 1 79  ? 32.60540  -13.29873 17.31962 1.000 85.20301  ? 70   PHE A HD1   1 
ATOM   1069 H  HD2   . PHE A 1 79  ? 36.35083  -14.30146 18.29515 1.000 92.32055  ? 70   PHE A HD2   1 
ATOM   1070 H  HE1   . PHE A 1 79  ? 32.69010  -11.53651 18.80600 1.000 88.55300  ? 70   PHE A HE1   1 
ATOM   1071 H  HE2   . PHE A 1 79  ? 36.44274  -12.53323 19.77141 1.000 86.43304  ? 70   PHE A HE2   1 
ATOM   1072 H  HZ    . PHE A 1 79  ? 34.61164  -11.14851 20.03232 1.000 92.17219  ? 70   PHE A HZ    1 
ATOM   1073 N  N     . CYS A 1 80  ? 34.25212  -17.49970 18.85463 1.000 79.75615  ? 71   CYS A N     1 
ATOM   1074 C  CA    . CYS A 1 80  ? 34.44178  -17.88325 20.24605 1.000 79.60017  ? 71   CYS A CA    1 
ATOM   1075 C  C     . CYS A 1 80  ? 35.11569  -16.75427 21.01183 1.000 75.64800  ? 71   CYS A C     1 
ATOM   1076 O  O     . CYS A 1 80  ? 36.09429  -16.16809 20.53959 1.000 75.01125  ? 71   CYS A O     1 
ATOM   1077 C  CB    . CYS A 1 80  ? 35.28565  -19.15023 20.33250 1.000 79.49614  ? 71   CYS A CB    1 
ATOM   1078 S  SG    . CYS A 1 80  ? 34.57078  -20.56863 19.49324 1.000 72.69974  ? 71   CYS A SG    1 
ATOM   1079 H  H     . CYS A 1 80  ? 34.72313  -17.95239 18.29532 1.000 95.75060  ? 71   CYS A H     1 
ATOM   1080 H  HA    . CYS A 1 80  ? 33.57919  -18.06163 20.65227 1.000 95.56341  ? 71   CYS A HA    1 
ATOM   1081 H  HB2   . CYS A 1 80  ? 36.15052  -18.97488 19.92982 1.000 95.43858  ? 71   CYS A HB2   1 
ATOM   1082 H  HB3   . CYS A 1 80  ? 35.39640  -19.38593 21.26688 1.000 95.43858  ? 71   CYS A HB3   1 
ATOM   1083 N  N     . ALA A 1 81  ? 34.59918  -16.45522 22.20048 1.000 73.98473  ? 72   ALA A N     1 
ATOM   1084 C  CA    . ALA A 1 81  ? 35.15297  -15.37499 23.00191 1.000 74.11311  ? 72   ALA A CA    1 
ATOM   1085 C  C     . ALA A 1 81  ? 34.70222  -15.53672 24.44380 1.000 71.35305  ? 72   ALA A C     1 
ATOM   1086 O  O     . ALA A 1 81  ? 33.71118  -16.21210 24.73422 1.000 74.07705  ? 72   ALA A O     1 
ATOM   1087 C  CB    . ALA A 1 81  ? 34.72820  -14.00394 22.46308 1.000 77.89767  ? 72   ALA A CB    1 
ATOM   1088 H  H     . ALA A 1 81  ? 33.93232  -16.86175 22.56053 1.000 88.82489  ? 72   ALA A H     1 
ATOM   1089 H  HA    . ALA A 1 81  ? 36.12099  -15.43304 22.98053 1.000 88.97895  ? 72   ALA A HA    1 
ATOM   1090 H  HB1   . ALA A 1 81  ? 35.13210  -13.31118 23.00884 1.000 93.52042  ? 72   ALA A HB1   1 
ATOM   1091 H  HB2   . ALA A 1 81  ? 35.02853  -13.91869 21.54470 1.000 93.52042  ? 72   ALA A HB2   1 
ATOM   1092 H  HB3   . ALA A 1 81  ? 33.76149  -13.93472 22.50274 1.000 93.52042  ? 72   ALA A HB3   1 
ATOM   1093 N  N     . ALA A 1 82  ? 35.45645  -14.91177 25.34514 1.000 72.02632  ? 73   ALA A N     1 
ATOM   1094 C  CA    . ALA A 1 82  ? 35.01950  -14.79658 26.72837 1.000 71.29267  ? 73   ALA A CA    1 
ATOM   1095 C  C     . ALA A 1 82  ? 33.71827  -14.00753 26.78421 1.000 62.01939  ? 73   ALA A C     1 
ATOM   1096 O  O     . ALA A 1 82  ? 33.56285  -12.98766 26.10748 1.000 63.18461  ? 73   ALA A O     1 
ATOM   1097 C  CB    . ALA A 1 82  ? 36.09484  -14.11379 27.57062 1.000 71.52771  ? 73   ALA A CB    1 
ATOM   1098 H  H     . ALA A 1 82  ? 36.21886  -14.54943 25.18068 1.000 86.47480  ? 73   ALA A H     1 
ATOM   1099 H  HA    . ALA A 1 82  ? 34.86940  -15.67770 27.10519 1.000 85.59441  ? 73   ALA A HA    1 
ATOM   1100 H  HB1   . ALA A 1 82  ? 35.78214  -14.04445 28.48621 1.000 85.87646  ? 73   ALA A HB1   1 
ATOM   1101 H  HB2   . ALA A 1 82  ? 36.90618  -14.64438 27.53746 1.000 85.87646  ? 73   ALA A HB2   1 
ATOM   1102 H  HB3   . ALA A 1 82  ? 36.26334  -13.22893 27.21072 1.000 85.87646  ? 73   ALA A HB3   1 
ATOM   1103 N  N     . CYS A 1 83  ? 32.77788  -14.48438 27.60059 1.000 58.37366  ? 74   CYS A N     1 
ATOM   1104 C  CA    . CYS A 1 83  ? 31.42399  -13.94197 27.55311 1.000 60.26194  ? 74   CYS A CA    1 
ATOM   1105 C  C     . CYS A 1 83  ? 31.40157  -12.44795 27.85555 1.000 59.65659  ? 74   CYS A C     1 
ATOM   1106 O  O     . CYS A 1 83  ? 30.60670  -11.70295 27.26977 1.000 56.71262  ? 74   CYS A O     1 
ATOM   1107 C  CB    . CYS A 1 83  ? 30.52420  -14.69686 28.52832 1.000 60.48244  ? 74   CYS A CB    1 
ATOM   1108 S  SG    . CYS A 1 83  ? 28.80737  -14.16382 28.47746 1.000 57.31587  ? 74   CYS A SG    1 
ATOM   1109 H  H     . CYS A 1 83  ? 32.89632  -15.10933 28.17938 1.000 70.09160  ? 74   CYS A H     1 
ATOM   1110 H  HA    . CYS A 1 83  ? 31.07567  -14.06672 26.65644 1.000 72.35755  ? 74   CYS A HA    1 
ATOM   1111 H  HB2   . CYS A 1 83  ? 30.54901  -15.64158 28.30969 1.000 72.62215  ? 74   CYS A HB2   1 
ATOM   1112 H  HB3   . CYS A 1 83  ? 30.85278  -14.55628 29.43008 1.000 72.62215  ? 74   CYS A HB3   1 
ATOM   1113 N  N     . HIS A 1 84  ? 32.26286  -11.98812 28.76507 1.000 57.42765  ? 75   HIS A N     1 
ATOM   1114 C  CA    . HIS A 1 84  ? 32.25192  -10.57689 29.13628 1.000 55.89309  ? 75   HIS A CA    1 
ATOM   1115 C  C     . HIS A 1 84  ? 32.88856  -9.70262  28.06353 1.000 54.98547  ? 75   HIS A C     1 
ATOM   1116 O  O     . HIS A 1 84  ? 32.45187  -8.56627  27.84814 1.000 51.58721  ? 75   HIS A O     1 
ATOM   1117 C  CB    . HIS A 1 84  ? 32.96192  -10.37961 30.47344 1.000 58.72493  ? 75   HIS A CB    1 
ATOM   1118 C  CG    . HIS A 1 84  ? 32.09272  -10.65679 31.65852 1.000 61.93033  ? 75   HIS A CG    1 
ATOM   1119 N  ND1   . HIS A 1 84  ? 31.80625  -11.93413 32.08992 1.000 65.70760  ? 75   HIS A ND1   1 
ATOM   1120 C  CD2   . HIS A 1 84  ? 31.43456  -9.82002  32.49508 1.000 64.40344  ? 75   HIS A CD2   1 
ATOM   1121 C  CE1   . HIS A 1 84  ? 31.01465  -11.87218 33.14559 1.000 62.21629  ? 75   HIS A CE1   1 
ATOM   1122 N  NE2   . HIS A 1 84  ? 30.77415  -10.60075 33.41189 1.000 68.20342  ? 75   HIS A NE2   1 
ATOM   1123 H  H     . HIS A 1 84  ? 32.85136  -12.46440 29.17302 1.000 68.95640  ? 75   HIS A H     1 
ATOM   1124 H  HA    . HIS A 1 84  ? 31.32995  -10.29402 29.24052 1.000 67.11492  ? 75   HIS A HA    1 
ATOM   1125 H  HB2   . HIS A 1 84  ? 33.72192  -10.98089 30.51557 1.000 70.51313  ? 75   HIS A HB2   1 
ATOM   1126 H  HB3   . HIS A 1 84  ? 33.26299  -9.45956  30.53480 1.000 70.51313  ? 75   HIS A HB3   1 
ATOM   1127 H  HD2   . HIS A 1 84  ? 31.43046  -8.89085  32.45618 1.000 77.32735  ? 75   HIS A HD2   1 
ATOM   1128 H  HE1   . HIS A 1 84  ? 30.68307  -12.59977 33.62053 1.000 74.70276  ? 75   HIS A HE1   1 
ATOM   1129 H  HE2   . HIS A 1 84  ? 30.28348  -10.30917 34.05518 1.000 81.88732  ? 75   HIS A HE2   1 
ATOM   1130 N  N     . GLY A 1 85  ? 33.92924  -10.19892 27.39583 1.000 55.31492  ? 76   GLY A N     1 
ATOM   1131 C  CA    . GLY A 1 85  ? 34.44535  -9.48718  26.23934 1.000 58.38501  ? 76   GLY A CA    1 
ATOM   1132 C  C     . GLY A 1 85  ? 33.42533  -9.41134  25.12036 1.000 57.67447  ? 76   GLY A C     1 
ATOM   1133 O  O     . GLY A 1 85  ? 33.23933  -8.36005  24.50273 1.000 58.70507  ? 76   GLY A O     1 
ATOM   1134 H  H     . GLY A 1 85  ? 34.34216  -10.92803 27.58945 1.000 66.42112  ? 76   GLY A H     1 
ATOM   1135 H  HA2   . GLY A 1 85  ? 34.68681  -8.58386  26.49746 1.000 70.10522  ? 76   GLY A HA2   1 
ATOM   1136 H  HA3   . GLY A 1 85  ? 35.23461  -9.94203  25.90607 1.000 70.10522  ? 76   GLY A HA3   1 
ATOM   1137 N  N     . CYS A 1 86  ? 32.74606  -10.52655 24.84848 1.000 53.41934  ? 77   CYS A N     1 
ATOM   1138 C  CA    . CYS A 1 86  ? 31.64213  -10.50690 23.89776 1.000 57.85507  ? 77   CYS A CA    1 
ATOM   1139 C  C     . CYS A 1 86  ? 30.57856  -9.49721  24.31004 1.000 57.10338  ? 77   CYS A C     1 
ATOM   1140 O  O     . CYS A 1 86  ? 29.97976  -8.82977  23.45762 1.000 52.84805  ? 77   CYS A O     1 
ATOM   1141 C  CB    . CYS A 1 86  ? 31.03127  -11.90080 23.78717 1.000 59.63910  ? 77   CYS A CB    1 
ATOM   1142 S  SG    . CYS A 1 86  ? 29.63858  -11.97984 22.66242 1.000 48.87144  ? 77   CYS A SG    1 
ATOM   1143 H  H     . CYS A 1 86  ? 32.90385  -11.29655 25.19747 1.000 64.14643  ? 77   CYS A H     1 
ATOM   1144 H  HA    . CYS A 1 86  ? 31.98234  -10.25021 23.02640 1.000 69.46930  ? 77   CYS A HA    1 
ATOM   1145 H  HB2   . CYS A 1 86  ? 31.70933  -12.51520 23.46521 1.000 71.61014  ? 77   CYS A HB2   1 
ATOM   1146 H  HB3   . CYS A 1 86  ? 30.72210  -12.17766 24.66390 1.000 71.61014  ? 77   CYS A HB3   1 
ATOM   1147 N  N     . LEU A 1 87  ? 30.32732  -9.37560  25.61632 1.000 54.84242  ? 78   LEU A N     1 
ATOM   1148 C  CA    A LEU A 1 87  ? 29.31173  -8.44139  26.09363 0.684 53.41544  ? 78   LEU A CA    1 
ATOM   1149 C  CA    B LEU A 1 87  ? 29.30731  -8.44605  26.08460 0.316 55.19956  ? 78   LEU A CA    1 
ATOM   1150 C  C     . LEU A 1 87  ? 29.67971  -7.00492  25.74939 1.000 53.37209  ? 78   LEU A C     1 
ATOM   1151 O  O     . LEU A 1 87  ? 28.83141  -6.22689  25.29617 1.000 52.62226  ? 78   LEU A O     1 
ATOM   1152 C  CB    A LEU A 1 87  ? 29.12872  -8.58301  27.60442 0.684 60.20792  ? 78   LEU A CB    1 
ATOM   1153 C  CB    B LEU A 1 87  ? 29.09248  -8.62760  27.58468 0.316 53.77360  ? 78   LEU A CB    1 
ATOM   1154 C  CG    A LEU A 1 87  ? 28.18672  -9.66058  28.14078 0.684 56.26378  ? 78   LEU A CG    1 
ATOM   1155 C  CG    B LEU A 1 87  ? 27.94051  -7.84521  28.21473 0.316 57.06142  ? 78   LEU A CG    1 
ATOM   1156 C  CD1   A LEU A 1 87  ? 28.29009  -9.72931  29.65912 0.684 54.25508  ? 78   LEU A CD1   1 
ATOM   1157 C  CD1   B LEU A 1 87  ? 26.63502  -8.07906  27.47142 0.316 56.04971  ? 78   LEU A CD1   1 
ATOM   1158 C  CD2   A LEU A 1 87  ? 26.75102  -9.38986  27.71684 0.684 56.47099  ? 78   LEU A CD2   1 
ATOM   1159 C  CD2   B LEU A 1 87  ? 27.79218  -8.24339  29.67123 0.316 55.95167  ? 78   LEU A CD2   1 
ATOM   1160 H  H     . LEU A 1 87  ? 30.72436  -9.81547  26.23959 1.000 65.85412  ? 78   LEU A H     1 
ATOM   1161 H  HA    . LEU A 1 87  ? 28.47013  -8.65739  25.66240 1.000 66.28268  ? 78   LEU A HA    1 
ATOM   1162 H  HB2   A LEU A 1 87  ? 30.00111  -8.76711  27.98645 0.684 72.29272  ? 78   LEU A HB2   1 
ATOM   1163 H  HB2   B LEU A 1 87  ? 28.92153  -9.56782  27.75101 0.316 64.57154  ? 78   LEU A HB2   1 
ATOM   1164 H  HB3   A LEU A 1 87  ? 28.79308  -7.73579  27.93679 0.684 72.29272  ? 78   LEU A HB3   1 
ATOM   1165 H  HB3   B LEU A 1 87  ? 29.90429  -8.35260  28.03882 0.316 64.57154  ? 78   LEU A HB3   1 
ATOM   1166 H  HG    A LEU A 1 87  ? 28.44425  -10.51965 27.77122 0.684 67.55975  ? 78   LEU A HG    1 
ATOM   1167 H  HG    B LEU A 1 87  ? 28.13863  -6.89728  28.15921 0.316 68.51692  ? 78   LEU A HG    1 
ATOM   1168 H  HD11  A LEU A 1 87  ? 27.71269  -10.43818 29.98320 0.684 65.14932  ? 78   LEU A HD11  1 
ATOM   1169 H  HD11  B LEU A 1 87  ? 25.91895  -7.62151  27.93917 0.316 67.30286  ? 78   LEU A HD11  1 
ATOM   1170 H  HD12  A LEU A 1 87  ? 29.21012  -9.91368  29.90500 0.684 65.14932  ? 78   LEU A HD12  1 
ATOM   1171 H  HD12  B LEU A 1 87  ? 26.71773  -7.72968  26.57031 0.316 67.30286  ? 78   LEU A HD12  1 
ATOM   1172 H  HD13  A LEU A 1 87  ? 28.01175  -8.87883  30.03343 0.684 65.14932  ? 78   LEU A HD13  1 
ATOM   1173 H  HD13  B LEU A 1 87  ? 26.45488  -9.03172  27.44158 0.316 67.30286  ? 78   LEU A HD13  1 
ATOM   1174 H  HD21  A LEU A 1 87  ? 26.17160  -10.05418 28.12163 0.684 67.80840  ? 78   LEU A HD21  1 
ATOM   1175 H  HD21  B LEU A 1 87  ? 27.19997  -7.61413  30.11192 0.316 67.18522  ? 78   LEU A HD21  1 
ATOM   1176 H  HD22  A LEU A 1 87  ? 26.49573  -8.50272  28.01468 0.684 67.80840  ? 78   LEU A HD22  1 
ATOM   1177 H  HD22  B LEU A 1 87  ? 27.41867  -9.13739  29.71775 0.316 67.18522  ? 78   LEU A HD22  1 
ATOM   1178 H  HD23  A LEU A 1 87  ? 26.69161  -9.44409  26.75018 0.684 67.80840  ? 78   LEU A HD23  1 
ATOM   1179 H  HD23  B LEU A 1 87  ? 28.66529  -8.22731  30.09351 0.316 67.18522  ? 78   LEU A HD23  1 
ATOM   1180 N  N     . PHE A 1 88  ? 30.94360  -6.62983  25.96724 1.000 56.05798  ? 79   PHE A N     1 
ATOM   1181 C  CA    . PHE A 1 88  ? 31.37866  -5.28266  25.61289 1.000 57.97948  ? 79   PHE A CA    1 
ATOM   1182 C  C     . PHE A 1 88  ? 31.21207  -5.03630  24.11807 1.000 51.87921  ? 79   PHE A C     1 
ATOM   1183 O  O     . PHE A 1 88  ? 30.75107  -3.96445  23.70194 1.000 48.06575  ? 79   PHE A O     1 
ATOM   1184 C  CB    . PHE A 1 88  ? 32.83598  -5.07102  26.02753 1.000 53.30260  ? 79   PHE A CB    1 
ATOM   1185 C  CG    . PHE A 1 88  ? 33.35608  -3.69994  25.71267 1.000 54.76920  ? 79   PHE A CG    1 
ATOM   1186 C  CD1   . PHE A 1 88  ? 33.24834  -2.67931  26.63896 1.000 54.87586  ? 79   PHE A CD1   1 
ATOM   1187 C  CD2   . PHE A 1 88  ? 33.93981  -3.42651  24.48587 1.000 56.31225  ? 79   PHE A CD2   1 
ATOM   1188 C  CE1   . PHE A 1 88  ? 33.71908  -1.41220  26.35286 1.000 51.72386  ? 79   PHE A CE1   1 
ATOM   1189 C  CE2   . PHE A 1 88  ? 34.41117  -2.16037  24.19405 1.000 57.73552  ? 79   PHE A CE2   1 
ATOM   1190 C  CZ    . PHE A 1 88  ? 34.30050  -1.15333  25.12927 1.000 51.25796  ? 79   PHE A CZ    1 
ATOM   1191 H  H     . PHE A 1 88  ? 31.55447  -7.12750  26.31186 1.000 67.31280  ? 79   PHE A H     1 
ATOM   1192 H  HA    . PHE A 1 88  ? 30.83476  -4.63983  26.09439 1.000 69.61859  ? 79   PHE A HA    1 
ATOM   1193 H  HB2   . PHE A 1 88  ? 32.91095  -5.20420  26.98541 1.000 64.00634  ? 79   PHE A HB2   1 
ATOM   1194 H  HB3   . PHE A 1 88  ? 33.39088  -5.71387  25.55877 1.000 64.00634  ? 79   PHE A HB3   1 
ATOM   1195 H  HD1   . PHE A 1 88  ? 32.85435  -2.84761  27.46440 1.000 65.89425  ? 79   PHE A HD1   1 
ATOM   1196 H  HD2   . PHE A 1 88  ? 34.01525  -4.10260  23.85175 1.000 67.61791  ? 79   PHE A HD2   1 
ATOM   1197 H  HE1   . PHE A 1 88  ? 33.64392  -0.73423  26.98501 1.000 62.11184  ? 79   PHE A HE1   1 
ATOM   1198 H  HE2   . PHE A 1 88  ? 34.80237  -1.98798  23.36813 1.000 69.32584  ? 79   PHE A HE2   1 
ATOM   1199 H  HZ    . PHE A 1 88  ? 34.61742  -0.30078  24.93532 1.000 61.55276  ? 79   PHE A HZ    1 
ATOM   1200 N  N     . ILE A 1 89  ? 31.59508  -6.01736  23.29622 1.000 49.52370  ? 80   ILE A N     1 
ATOM   1201 C  CA    . ILE A 1 89  ? 31.38997  -5.91710  21.85246 1.000 57.04044  ? 80   ILE A CA    1 
ATOM   1202 C  C     . ILE A 1 89  ? 29.92605  -5.63860  21.54670 1.000 46.16544  ? 80   ILE A C     1 
ATOM   1203 O  O     . ILE A 1 89  ? 29.60009  -4.87292  20.63240 1.000 46.27083  ? 80   ILE A O     1 
ATOM   1204 C  CB    . ILE A 1 89  ? 31.87726  -7.20394  21.15558 1.000 56.64603  ? 80   ILE A CB    1 
ATOM   1205 C  CG1   . ILE A 1 89  ? 33.32206  -7.05195  20.67969 1.000 60.03204  ? 80   ILE A CG1   1 
ATOM   1206 C  CG2   . ILE A 1 89  ? 30.99269  -7.56394  19.96045 1.000 59.48603  ? 80   ILE A CG2   1 
ATOM   1207 C  CD1   . ILE A 1 89  ? 34.27490  -6.64451  21.75715 1.000 65.46801  ? 80   ILE A CD1   1 
ATOM   1208 H  H     . ILE A 1 89  ? 31.97378  -6.74696  23.54894 1.000 59.47166  ? 80   ILE A H     1 
ATOM   1209 H  HA    . ILE A 1 89  ? 31.91504  -5.17502  21.51406 1.000 68.49175  ? 80   ILE A HA    1 
ATOM   1210 H  HB    . ILE A 1 89  ? 31.82509  -7.91558  21.81266 1.000 68.01845  ? 80   ILE A HB    1 
ATOM   1211 H  HG12  . ILE A 1 89  ? 33.62395  -7.90258  20.32446 1.000 72.08167  ? 80   ILE A HG12  1 
ATOM   1212 H  HG13  . ILE A 1 89  ? 33.35192  -6.37370  19.98688 1.000 72.08167  ? 80   ILE A HG13  1 
ATOM   1213 H  HG21  . ILE A 1 89  ? 31.41997  -8.27174  19.45316 1.000 71.42645  ? 80   ILE A HG21  1 
ATOM   1214 H  HG22  . ILE A 1 89  ? 30.12966  -7.86461  20.28554 1.000 71.42645  ? 80   ILE A HG22  1 
ATOM   1215 H  HG23  . ILE A 1 89  ? 30.88063  -6.77840  19.40253 1.000 71.42645  ? 80   ILE A HG23  1 
ATOM   1216 H  HD11  . ILE A 1 89  ? 35.18275  -6.78255  21.44466 1.000 78.60482  ? 80   ILE A HD11  1 
ATOM   1217 H  HD12  . ILE A 1 89  ? 34.13531  -5.70722  21.96432 1.000 78.60482  ? 80   ILE A HD12  1 
ATOM   1218 H  HD13  . ILE A 1 89  ? 34.11049  -7.18552  22.54529 1.000 78.60482  ? 80   ILE A HD13  1 
ATOM   1219 N  N     . ALA A 1 90  ? 29.02097  -6.25320  22.30913 1.000 47.05042  ? 81   ALA A N     1 
ATOM   1220 C  CA    . ALA A 1 90  ? 27.59855  -6.13780  22.01481 1.000 50.06837  ? 81   ALA A CA    1 
ATOM   1221 C  C     . ALA A 1 90  ? 26.99863  -4.83235  22.52408 1.000 46.80282  ? 81   ALA A C     1 
ATOM   1222 O  O     . ALA A 1 90  ? 26.11427  -4.26985  21.86802 1.000 47.39067  ? 81   ALA A O     1 
ATOM   1223 C  CB    . ALA A 1 90  ? 26.84289  -7.32358  22.61942 1.000 44.29381  ? 81   ALA A CB    1 
ATOM   1224 H  H     . ALA A 1 90  ? 29.20496  -6.73774  22.99541 1.000 56.50372  ? 81   ALA A H     1 
ATOM   1225 H  HA    . ALA A 1 90  ? 27.48435  -6.15862  21.05179 1.000 60.12526  ? 81   ALA A HA    1 
ATOM   1226 H  HB1   . ALA A 1 90  ? 25.90013  -7.23840  22.40765 1.000 53.19578  ? 81   ALA A HB1   1 
ATOM   1227 H  HB2   . ALA A 1 90  ? 27.19334  -8.14623  22.24348 1.000 53.19578  ? 81   ALA A HB2   1 
ATOM   1228 H  HB3   . ALA A 1 90  ? 26.96744  -7.32010  23.58139 1.000 53.19578  ? 81   ALA A HB3   1 
ATOM   1229 N  N     . CYS A 1 91  ? 27.46812  -4.32831  23.66672 1.000 43.58536  ? 82   CYS A N     1 
ATOM   1230 C  CA    . CYS A 1 91  ? 26.80068  -3.23497  24.35948 1.000 48.13368  ? 82   CYS A CA    1 
ATOM   1231 C  C     . CYS A 1 91  ? 27.40224  -1.86547  24.07243 1.000 42.67964  ? 82   CYS A C     1 
ATOM   1232 O  O     . CYS A 1 91  ? 26.78405  -0.85380  24.42218 1.000 44.41219  ? 82   CYS A O     1 
ATOM   1233 C  CB    . CYS A 1 91  ? 26.82435  -3.48274  25.87573 1.000 52.83862  ? 82   CYS A CB    1 
ATOM   1234 S  SG    . CYS A 1 91  ? 26.00208  -5.00402  26.40958 1.000 66.28749  ? 82   CYS A SG    1 
ATOM   1235 H  H     . CYS A 1 91  ? 28.17906  -4.60823  24.06146 1.000 52.34564  ? 82   CYS A H     1 
ATOM   1236 H  HA    . CYS A 1 91  ? 25.87642  -3.21175  24.06604 1.000 57.80363  ? 82   CYS A HA    1 
ATOM   1237 H  HB2   . CYS A 1 91  ? 27.74891  -3.53404  26.16463 1.000 63.44956  ? 82   CYS A HB2   1 
ATOM   1238 H  HB3   . CYS A 1 91  ? 26.37998  -2.74115  26.31558 1.000 63.44956  ? 82   CYS A HB3   1 
ATOM   1239 H  HG    . CYS A 1 91  ? 26.07677  -5.08997  27.60416 1.000 79.58821  ? 82   CYS A HG    1 
ATOM   1240 N  N     . PHE A 1 92  ? 28.58358  -1.79781  23.45374 1.000 43.20019  ? 83   PHE A N     1 
ATOM   1241 C  CA    . PHE A 1 92  ? 29.19354  -0.49450  23.21251 1.000 45.80761  ? 83   PHE A CA    1 
ATOM   1242 C  C     . PHE A 1 92  ? 28.29612  0.37936   22.34564 1.000 48.83691  ? 83   PHE A C     1 
ATOM   1243 O  O     . PHE A 1 92  ? 28.24192  1.60179   22.53615 1.000 41.46316  ? 83   PHE A O     1 
ATOM   1244 C  CB    . PHE A 1 92  ? 30.56795  -0.66214  22.56355 1.000 46.94165  ? 83   PHE A CB    1 
ATOM   1245 C  CG    . PHE A 1 92  ? 31.26956  0.64096   22.29455 1.000 47.43019  ? 83   PHE A CG    1 
ATOM   1246 C  CD1   . PHE A 1 92  ? 31.90211  1.32956   23.31716 1.000 46.73615  ? 83   PHE A CD1   1 
ATOM   1247 C  CD2   . PHE A 1 92  ? 31.29056  1.18051   21.02008 1.000 49.34259  ? 83   PHE A CD2   1 
ATOM   1248 C  CE1   . PHE A 1 92  ? 32.54250  2.52958   23.07110 1.000 47.66735  ? 83   PHE A CE1   1 
ATOM   1249 C  CE2   . PHE A 1 92  ? 31.93100  2.37963   20.76961 1.000 52.95671  ? 83   PHE A CE2   1 
ATOM   1250 C  CZ    . PHE A 1 92  ? 32.55573  3.05437   21.79582 1.000 47.28792  ? 83   PHE A CZ    1 
ATOM   1251 H  H     . PHE A 1 92  ? 29.03736  -2.47220  23.17290 1.000 51.88344  ? 83   PHE A H     1 
ATOM   1252 H  HA    . PHE A 1 92  ? 29.32519  -0.04617  24.06255 1.000 55.01235  ? 83   PHE A HA    1 
ATOM   1253 H  HB2   . PHE A 1 92  ? 31.13100  -1.18580  23.15487 1.000 56.37320  ? 83   PHE A HB2   1 
ATOM   1254 H  HB3   . PHE A 1 92  ? 30.45948  -1.12128  21.71601 1.000 56.37320  ? 83   PHE A HB3   1 
ATOM   1255 H  HD1   . PHE A 1 92  ? 31.89573  0.98028   24.17905 1.000 56.12659  ? 83   PHE A HD1   1 
ATOM   1256 H  HD2   . PHE A 1 92  ? 30.86869  0.73084   20.32386 1.000 59.25433  ? 83   PHE A HD2   1 
ATOM   1257 H  HE1   . PHE A 1 92  ? 32.96418  2.98280   23.76514 1.000 57.24404  ? 83   PHE A HE1   1 
ATOM   1258 H  HE2   . PHE A 1 92  ? 31.94022  2.73094   19.90857 1.000 63.59126  ? 83   PHE A HE2   1 
ATOM   1259 H  HZ    . PHE A 1 92  ? 32.98544  3.86205   21.62878 1.000 56.78872  ? 83   PHE A HZ    1 
ATOM   1260 N  N     . VAL A 1 93  ? 27.57615  -0.22540  21.40030 1.000 44.89396  ? 84   VAL A N     1 
ATOM   1261 C  CA    . VAL A 1 93  ? 26.65796  0.55301   20.57877 1.000 42.43136  ? 84   VAL A CA    1 
ATOM   1262 C  C     . VAL A 1 93  ? 25.51745  1.10298   21.42863 1.000 45.20010  ? 84   VAL A C     1 
ATOM   1263 O  O     . VAL A 1 93  ? 24.98349  2.18089   21.13933 1.000 39.65861  ? 84   VAL A O     1 
ATOM   1264 C  CB    . VAL A 1 93  ? 26.13917  -0.29704  19.40303 1.000 41.22370  ? 84   VAL A CB    1 
ATOM   1265 C  CG1   . VAL A 1 93  ? 25.23587  -1.41767  19.89746 1.000 42.65656  ? 84   VAL A CG1   1 
ATOM   1266 C  CG2   . VAL A 1 93  ? 25.41522  0.58027   18.39509 1.000 40.38079  ? 84   VAL A CG2   1 
ATOM   1267 H  H     . VAL A 1 93  ? 27.60140  -1.06588  21.21987 1.000 53.91597  ? 84   VAL A H     1 
ATOM   1268 H  HA    . VAL A 1 93  ? 27.13901  1.30768   20.20465 1.000 50.96084  ? 84   VAL A HA    1 
ATOM   1269 H  HB    . VAL A 1 93  ? 26.89658  -0.70782  18.95751 1.000 49.51166  ? 84   VAL A HB    1 
ATOM   1270 H  HG11  . VAL A 1 93  ? 25.03513  -2.01139  19.15712 1.000 51.23109  ? 84   VAL A HG11  1 
ATOM   1271 H  HG12  . VAL A 1 93  ? 25.69422  -1.90663  20.59869 1.000 51.23109  ? 84   VAL A HG12  1 
ATOM   1272 H  HG13  . VAL A 1 93  ? 24.41594  -1.03259  20.24434 1.000 51.23109  ? 84   VAL A HG13  1 
ATOM   1273 H  HG21  . VAL A 1 93  ? 25.13290  0.03317   17.64550 1.000 48.50017  ? 84   VAL A HG21  1 
ATOM   1274 H  HG22  . VAL A 1 93  ? 24.64176  0.98019   18.82255 1.000 48.50017  ? 84   VAL A HG22  1 
ATOM   1275 H  HG23  . VAL A 1 93  ? 26.01970  1.27434   18.08888 1.000 48.50017  ? 84   VAL A HG23  1 
ATOM   1276 N  N     . LEU A 1 94  ? 25.12664  0.38634   22.48693 1.000 46.62694  ? 85   LEU A N     1 
ATOM   1277 C  CA    . LEU A 1 94  ? 24.12986  0.92057   23.41030 1.000 46.09191  ? 85   LEU A CA    1 
ATOM   1278 C  C     . LEU A 1 94  ? 24.63217  2.19427   24.07720 1.000 47.18871  ? 85   LEU A C     1 
ATOM   1279 O  O     . LEU A 1 94  ? 23.85566  3.12602   24.32179 1.000 40.22999  ? 85   LEU A O     1 
ATOM   1280 C  CB    . LEU A 1 94  ? 23.77496  -0.12377  24.46718 1.000 45.13083  ? 85   LEU A CB    1 
ATOM   1281 C  CG    . LEU A 1 94  ? 23.19095  -1.42902  23.93091 1.000 50.83337  ? 85   LEU A CG    1 
ATOM   1282 C  CD1   . LEU A 1 94  ? 22.98947  -2.43455  25.05340 1.000 56.12398  ? 85   LEU A CD1   1 
ATOM   1283 C  CD2   . LEU A 1 94  ? 21.88281  -1.15545  23.21894 1.000 48.19189  ? 85   LEU A CD2   1 
ATOM   1284 H  H     . LEU A 1 94  ? 25.41898  -0.39721  22.68741 1.000 55.99555  ? 85   LEU A H     1 
ATOM   1285 H  HA    . LEU A 1 94  ? 23.32453  1.13041   22.91200 1.000 55.35351  ? 85   LEU A HA    1 
ATOM   1286 H  HB2   . LEU A 1 94  ? 24.58171  -0.34739  24.95715 1.000 54.20021  ? 85   LEU A HB2   1 
ATOM   1287 H  HB3   . LEU A 1 94  ? 23.11820  0.26196   25.06783 1.000 54.20021  ? 85   LEU A HB3   1 
ATOM   1288 H  HG    . LEU A 1 94  ? 23.81248  -1.81889  23.29641 1.000 61.04325  ? 85   LEU A HG    1 
ATOM   1289 H  HD11  . LEU A 1 94  ? 22.69585  -3.27736  24.67346 1.000 67.39199  ? 85   LEU A HD11  1 
ATOM   1290 H  HD12  . LEU A 1 94  ? 23.82998  -2.55776  25.52164 1.000 67.39199  ? 85   LEU A HD12  1 
ATOM   1291 H  HD13  . LEU A 1 94  ? 22.31703  -2.09509  25.66454 1.000 67.39199  ? 85   LEU A HD13  1 
ATOM   1292 H  HD21  . LEU A 1 94  ? 21.30634  -1.93038  23.30870 1.000 57.87348  ? 85   LEU A HD21  1 
ATOM   1293 H  HD22  . LEU A 1 94  ? 21.46033  -0.38052  23.62130 1.000 57.87348  ? 85   LEU A HD22  1 
ATOM   1294 H  HD23  . LEU A 1 94  ? 22.06333  -0.98428  22.28138 1.000 57.87348  ? 85   LEU A HD23  1 
ATOM   1295 N  N     . VAL A 1 95  ? 25.92763  2.24788   24.39345 1.000 44.25861  ? 86   VAL A N     1 
ATOM   1296 C  CA    . VAL A 1 95  ? 26.50302  3.47460   24.93737 1.000 44.30428  ? 86   VAL A CA    1 
ATOM   1297 C  C     . VAL A 1 95  ? 26.33152  4.61626   23.94213 1.000 42.58301  ? 86   VAL A C     1 
ATOM   1298 O  O     . VAL A 1 95  ? 25.84220  5.69899   24.28649 1.000 44.71132  ? 86   VAL A O     1 
ATOM   1299 C  CB    . VAL A 1 95  ? 27.98429  3.25816   25.29980 1.000 43.13626  ? 86   VAL A CB    1 
ATOM   1300 C  CG1   . VAL A 1 95  ? 28.62314  4.56263   25.76795 1.000 44.05664  ? 86   VAL A CG1   1 
ATOM   1301 C  CG2   . VAL A 1 95  ? 28.12027  2.17700   26.36780 1.000 45.99738  ? 86   VAL A CG2   1 
ATOM   1302 H  H     . VAL A 1 95  ? 26.48421  1.59844   24.30377 1.000 53.15354  ? 86   VAL A H     1 
ATOM   1303 H  HA    . VAL A 1 95  ? 26.02870  3.70832   25.75057 1.000 53.20835  ? 86   VAL A HA    1 
ATOM   1304 H  HB    . VAL A 1 95  ? 28.45848  2.96196   24.50714 1.000 51.80673  ? 86   VAL A HB    1 
ATOM   1305 H  HG11  . VAL A 1 95  ? 29.49901  4.37040   26.13780 1.000 52.91118  ? 86   VAL A HG11  1 
ATOM   1306 H  HG12  . VAL A 1 95  ? 28.70835  5.16227   25.01028 1.000 52.91118  ? 86   VAL A HG12  1 
ATOM   1307 H  HG13  . VAL A 1 95  ? 28.05864  4.96505   26.44641 1.000 52.91118  ? 86   VAL A HG13  1 
ATOM   1308 H  HG21  . VAL A 1 95  ? 29.04430  2.13625   26.66005 1.000 55.24007  ? 86   VAL A HG21  1 
ATOM   1309 H  HG22  . VAL A 1 95  ? 27.54584  2.39930   27.11714 1.000 55.24007  ? 86   VAL A HG22  1 
ATOM   1310 H  HG23  . VAL A 1 95  ? 27.85511  1.32414   25.98935 1.000 55.24007  ? 86   VAL A HG23  1 
ATOM   1311 N  N     . LEU A 1 96  ? 26.71817  4.38248   22.68473 1.000 40.93267  ? 87   LEU A N     1 
ATOM   1312 C  CA    . LEU A 1 96  ? 26.64563  5.43744   21.67931 1.000 46.07319  ? 87   LEU A CA    1 
ATOM   1313 C  C     . LEU A 1 96  ? 25.20637  5.86879   21.42931 1.000 47.32920  ? 87   LEU A C     1 
ATOM   1314 O  O     . LEU A 1 96  ? 24.93174  7.05857   21.23494 1.000 46.67898  ? 87   LEU A O     1 
ATOM   1315 C  CB    . LEU A 1 96  ? 27.28998  4.96602   20.37614 1.000 50.11676  ? 87   LEU A CB    1 
ATOM   1316 C  CG    . LEU A 1 96  ? 28.76582  4.57101   20.45135 1.000 53.21525  ? 87   LEU A CG    1 
ATOM   1317 C  CD1   . LEU A 1 96  ? 29.26327  4.12396   19.08250 1.000 46.38111  ? 87   LEU A CD1   1 
ATOM   1318 C  CD2   . LEU A 1 96  ? 29.61502  5.71656   20.98429 1.000 50.40172  ? 87   LEU A CD2   1 
ATOM   1319 H  H     . LEU A 1 96  ? 27.02154  3.63196   22.39441 1.000 49.16243  ? 87   LEU A H     1 
ATOM   1320 H  HA    . LEU A 1 96  ? 27.13997  6.20666   22.00310 1.000 55.33105  ? 87   LEU A HA    1 
ATOM   1321 H  HB2   . LEU A 1 96  ? 26.80187  4.18834   20.06330 1.000 60.18332  ? 87   LEU A HB2   1 
ATOM   1322 H  HB3   . LEU A 1 96  ? 27.21942  5.68465   19.72846 1.000 60.18332  ? 87   LEU A HB3   1 
ATOM   1323 H  HG    . LEU A 1 96  ? 28.85897  3.82833   21.06832 1.000 63.90151  ? 87   LEU A HG    1 
ATOM   1324 H  HD11  . LEU A 1 96  ? 30.20098  3.88506   19.14981 1.000 55.70055  ? 87   LEU A HD11  1 
ATOM   1325 H  HD12  . LEU A 1 96  ? 28.74609  3.35573   18.79397 1.000 55.70055  ? 87   LEU A HD12  1 
ATOM   1326 H  HD13  . LEU A 1 96  ? 29.15208  4.85308   18.45249 1.000 55.70055  ? 87   LEU A HD13  1 
ATOM   1327 H  HD21  . LEU A 1 96  ? 30.55022  5.46250   20.94231 1.000 60.52528  ? 87   LEU A HD21  1 
ATOM   1328 H  HD22  . LEU A 1 96  ? 29.46134  6.50387   20.43892 1.000 60.52528  ? 87   LEU A HD22  1 
ATOM   1329 H  HD23  . LEU A 1 96  ? 29.36200  5.89624   21.90331 1.000 60.52528  ? 87   LEU A HD23  1 
ATOM   1330 N  N     . ALA A 1 97  ? 24.27335  4.91587   21.41438 1.000 42.34766  ? 88   ALA A N     1 
ATOM   1331 C  CA    . ALA A 1 97  ? 22.87402  5.27245   21.21347 1.000 43.00309  ? 88   ALA A CA    1 
ATOM   1332 C  C     . ALA A 1 97  ? 22.35981  6.12668   22.36397 1.000 42.96163  ? 88   ALA A C     1 
ATOM   1333 O  O     . ALA A 1 97  ? 21.65698  7.12011   22.14490 1.000 39.69090  ? 88   ALA A O     1 
ATOM   1334 C  CB    . ALA A 1 97  ? 22.02561  4.01049   21.05916 1.000 36.24568  ? 88   ALA A CB    1 
ATOM   1335 H  H     . ALA A 1 97  ? 24.42245  4.07501   21.51605 1.000 50.86040  ? 88   ALA A H     1 
ATOM   1336 H  HA    . ALA A 1 97  ? 22.79432  5.78612   20.39451 1.000 51.64692  ? 88   ALA A HA    1 
ATOM   1337 H  HB1   . ALA A 1 97  ? 21.09842  4.26663   20.93424 1.000 43.53804  ? 88   ALA A HB1   1 
ATOM   1338 H  HB2   . ALA A 1 97  ? 22.33798  3.51233   20.28769 1.000 43.53804  ? 88   ALA A HB2   1 
ATOM   1339 H  HB3   . ALA A 1 97  ? 22.11455  3.47029   21.85989 1.000 43.53804  ? 88   ALA A HB3   1 
ATOM   1340 N  N     . GLN A 1 98  ? 22.70551  5.76169   23.59980 1.000 42.58689  ? 89   GLN A N     1 
ATOM   1341 C  CA    . GLN A 1 98  ? 22.23620  6.53657   24.74282 1.000 49.69980  ? 89   GLN A CA    1 
ATOM   1342 C  C     . GLN A 1 98  ? 22.82421  7.94117   24.72459 1.000 50.87254  ? 89   GLN A C     1 
ATOM   1343 O  O     . GLN A 1 98  ? 22.12993  8.91669   25.03442 1.000 43.31256  ? 89   GLN A O     1 
ATOM   1344 C  CB    . GLN A 1 98  ? 22.58825  5.82061   26.04534 1.000 49.20851  ? 89   GLN A CB    1 
ATOM   1345 C  CG    . GLN A 1 98  ? 21.74102  6.25952   27.22054 1.000 50.26219  ? 89   GLN A CG    1 
ATOM   1346 C  CD    . GLN A 1 98  ? 20.26192  6.03102   26.97782 1.000 54.49617  ? 89   GLN A CD    1 
ATOM   1347 O  OE1   . GLN A 1 98  ? 19.85922  4.98342   26.47270 1.000 53.51574  ? 89   GLN A OE1   1 
ATOM   1348 N  NE2   . GLN A 1 98  ? 19.44657  7.02111   27.31794 1.000 54.19358  ? 89   GLN A NE2   1 
ATOM   1349 H  H     . GLN A 1 98  ? 23.19896  5.08556   23.79717 1.000 51.14748  ? 89   GLN A H     1 
ATOM   1350 H  HA    . GLN A 1 98  ? 21.27007  6.61103   24.69857 1.000 59.68297  ? 89   GLN A HA    1 
ATOM   1351 H  HB2   . GLN A 1 98  ? 22.45763  4.86716   25.92382 1.000 59.09343  ? 89   GLN A HB2   1 
ATOM   1352 H  HB3   . GLN A 1 98  ? 23.51583  6.00339   26.26235 1.000 59.09343  ? 89   GLN A HB3   1 
ATOM   1353 H  HG2   . GLN A 1 98  ? 22.00012  5.75322   28.00630 1.000 60.35784  ? 89   GLN A HG2   1 
ATOM   1354 H  HG3   . GLN A 1 98  ? 21.87897  7.20699   27.37601 1.000 60.35784  ? 89   GLN A HG3   1 
ATOM   1355 H  HE21  . GLN A 1 98  ? 19.76609  7.74423   27.65648 1.000 65.07552  ? 89   GLN A HE21  1 
ATOM   1356 H  HE22  . GLN A 1 98  ? 18.59862  6.93968   27.19984 1.000 65.07552  ? 89   GLN A HE22  1 
ATOM   1357 N  N     . SER A 1 99  ? 24.10312  8.06203   24.36270 1.000 45.07433  ? 90   SER A N     1 
ATOM   1358 C  CA    . SER A 1 99  ? 24.70350  9.38113   24.20546 1.000 43.42619  ? 90   SER A CA    1 
ATOM   1359 C  C     . SER A 1 99  ? 23.93640  10.21364  23.18696 1.000 44.99328  ? 90   SER A C     1 
ATOM   1360 O  O     . SER A 1 99  ? 23.67393  11.40043  23.41412 1.000 49.20028  ? 90   SER A O     1 
ATOM   1361 C  CB    . SER A 1 99  ? 26.16494  9.23835   23.78708 1.000 46.54986  ? 90   SER A CB    1 
ATOM   1362 O  OG    . SER A 1 99  ? 26.65607  10.45237  23.24992 1.000 50.11235  ? 90   SER A OG    1 
ATOM   1363 H  H     . SER A 1 99  ? 24.63498  7.40484   24.20511 1.000 54.13241  ? 90   SER A H     1 
ATOM   1364 H  HA    . SER A 1 99  ? 24.67578  9.84509   25.05685 1.000 52.15465  ? 90   SER A HA    1 
ATOM   1365 H  HB2   . SER A 1 99  ? 26.69405  9.00009   24.56437 1.000 55.90304  ? 90   SER A HB2   1 
ATOM   1366 H  HB3   . SER A 1 99  ? 26.23407  8.54408   23.11320 1.000 55.90304  ? 90   SER A HB3   1 
ATOM   1367 H  HG    . SER A 1 99  ? 27.29783  10.29786  22.73043 1.000 60.17803  ? 90   SER A HG    1 
ATOM   1368 N  N     . SER A 1 100 ? 23.56987  9.60823   22.05491 1.000 43.50469  ? 91   SER A N     1 
ATOM   1369 C  CA    . SER A 1 100 ? 22.77222  10.31939  21.06165 1.000 48.85389  ? 91   SER A CA    1 
ATOM   1370 C  C     . SER A 1 100 ? 21.46222  10.81523  21.66324 1.000 51.71021  ? 91   SER A C     1 
ATOM   1371 O  O     . SER A 1 100 ? 21.06333  11.96598  21.44363 1.000 44.55496  ? 91   SER A O     1 
ATOM   1372 C  CB    . SER A 1 100 ? 22.49951  9.40846   19.86276 1.000 49.22030  ? 91   SER A CB    1 
ATOM   1373 O  OG    . SER A 1 100 ? 23.70803  8.95249   19.28012 1.000 51.38734  ? 91   SER A OG    1 
ATOM   1374 H  H     . SER A 1 100 ? 23.76786  8.79869   21.84267 1.000 52.24884  ? 91   SER A H     1 
ATOM   1375 H  HA    . SER A 1 100 ? 23.27195  11.08966  20.74884 1.000 58.66788  ? 91   SER A HA    1 
ATOM   1376 H  HB2   . SER A 1 100 ? 21.98552  8.64180   20.16103 1.000 59.10758  ? 91   SER A HB2   1 
ATOM   1377 H  HB3   . SER A 1 100 ? 21.99803  9.90573   19.19783 1.000 59.10758  ? 91   SER A HB3   1 
ATOM   1378 H  HG    . SER A 1 100 ? 24.15543  8.52225   19.84610 1.000 61.70802  ? 91   SER A HG    1 
ATOM   1379 N  N     . ILE A 1 101 ? 20.78160  9.95919   22.42963 1.000 53.55312  ? 92   ILE A N     1 
ATOM   1380 C  CA    . ILE A 1 101 ? 19.50483  10.33832  23.02915 1.000 50.58599  ? 92   ILE A CA    1 
ATOM   1381 C  C     . ILE A 1 101 ? 19.67942  11.54143  23.94644 1.000 51.03111  ? 92   ILE A C     1 
ATOM   1382 O  O     . ILE A 1 101 ? 18.87018  12.47724  23.92784 1.000 53.83956  ? 92   ILE A O     1 
ATOM   1383 C  CB    . ILE A 1 101 ? 18.89705  9.13808   23.78009 1.000 55.58871  ? 92   ILE A CB    1 
ATOM   1384 C  CG1   . ILE A 1 101 ? 18.42262  8.07501   22.78472 1.000 54.35325  ? 92   ILE A CG1   1 
ATOM   1385 C  CG2   . ILE A 1 101 ? 17.75205  9.59210   24.67167 1.000 53.46581  ? 92   ILE A CG2   1 
ATOM   1386 C  CD1   . ILE A 1 101 ? 18.26965  6.69622   23.38610 1.000 55.37448  ? 92   ILE A CD1   1 
ATOM   1387 H  H     . ILE A 1 101 ? 21.03645  9.15919   22.61581 1.000 64.30696  ? 92   ILE A H     1 
ATOM   1388 H  HA    . ILE A 1 101 ? 18.89469  10.59360  22.31960 1.000 60.74640  ? 92   ILE A HA    1 
ATOM   1389 H  HB    . ILE A 1 101 ? 19.58362  8.74672   24.34254 1.000 66.74967  ? 92   ILE A HB    1 
ATOM   1390 H  HG12  . ILE A 1 101 ? 17.55867  8.34135   22.43323 1.000 65.26712  ? 92   ILE A HG12  1 
ATOM   1391 H  HG13  . ILE A 1 101 ? 19.06906  8.01281   22.06420 1.000 65.26712  ? 92   ILE A HG13  1 
ATOM   1392 H  HG21  . ILE A 1 101 ? 17.23554  8.81676   24.94177 1.000 64.20219  ? 92   ILE A HG21  1 
ATOM   1393 H  HG22  . ILE A 1 101 ? 18.11717  10.03507  25.45357 1.000 64.20219  ? 92   ILE A HG22  1 
ATOM   1394 H  HG23  . ILE A 1 101 ? 17.19004  10.20737  24.17519 1.000 64.20219  ? 92   ILE A HG23  1 
ATOM   1395 H  HD11  . ILE A 1 101 ? 17.98201  6.08010   22.69432 1.000 66.49259  ? 92   ILE A HD11  1 
ATOM   1396 H  HD12  . ILE A 1 101 ? 19.12408  6.41263   23.74722 1.000 66.49259  ? 92   ILE A HD12  1 
ATOM   1397 H  HD13  . ILE A 1 101 ? 17.60700  6.73201   24.09357 1.000 66.49259  ? 92   ILE A HD13  1 
ATOM   1398 N  N     . PHE A 1 102 ? 20.73153  11.53574  24.76856 1.000 47.33688  ? 93   PHE A N     1 
ATOM   1399 C  CA    . PHE A 1 102 ? 20.96110  12.65635  25.67453 1.000 50.05264  ? 93   PHE A CA    1 
ATOM   1400 C  C     . PHE A 1 102 ? 21.25175  13.93794  24.90072 1.000 54.03682  ? 93   PHE A C     1 
ATOM   1401 O  O     . PHE A 1 102 ? 20.75272  15.01291  25.25486 1.000 54.03788  ? 93   PHE A O     1 
ATOM   1402 C  CB    . PHE A 1 102 ? 22.11133  12.33495  26.63100 1.000 56.91170  ? 93   PHE A CB    1 
ATOM   1403 C  CG    . PHE A 1 102 ? 21.75991  11.32850  27.69959 1.000 58.49412  ? 93   PHE A CG    1 
ATOM   1404 C  CD1   . PHE A 1 102 ? 20.50798  11.32909  28.29867 1.000 61.76604  ? 93   PHE A CD1   1 
ATOM   1405 C  CD2   . PHE A 1 102 ? 22.68869  10.38266  28.10618 1.000 56.53894  ? 93   PHE A CD2   1 
ATOM   1406 C  CE1   . PHE A 1 102 ? 20.19004  10.40436  29.27977 1.000 67.75804  ? 93   PHE A CE1   1 
ATOM   1407 C  CE2   . PHE A 1 102 ? 22.37789  9.45794   29.08611 1.000 60.33395  ? 93   PHE A CE2   1 
ATOM   1408 C  CZ    . PHE A 1 102 ? 21.12735  9.46777   29.67355 1.000 62.89297  ? 93   PHE A CZ    1 
ATOM   1409 H  H     . PHE A 1 102 ? 21.31533  10.90627  24.81910 1.000 56.84747  ? 93   PHE A H     1 
ATOM   1410 H  HA    . PHE A 1 102 ? 20.16146  12.79763  26.20510 1.000 60.10638  ? 93   PHE A HA    1 
ATOM   1411 H  HB2   . PHE A 1 102 ? 22.85073  11.97367  26.11750 1.000 68.33725  ? 93   PHE A HB2   1 
ATOM   1412 H  HB3   . PHE A 1 102 ? 22.38415  13.15312  27.07491 1.000 68.33725  ? 93   PHE A HB3   1 
ATOM   1413 H  HD1   . PHE A 1 102 ? 19.87458  11.95823  28.03812 1.000 74.16246  ? 93   PHE A HD1   1 
ATOM   1414 H  HD2   . PHE A 1 102 ? 23.53210  10.37004  27.71451 1.000 67.88994  ? 93   PHE A HD2   1 
ATOM   1415 H  HE1   . PHE A 1 102 ? 19.34728  10.41363  29.67293 1.000 81.35287  ? 93   PHE A HE1   1 
ATOM   1416 H  HE2   . PHE A 1 102 ? 23.01058  8.82939   29.34979 1.000 72.44395  ? 93   PHE A HE2   1 
ATOM   1417 H  HZ    . PHE A 1 102 ? 20.91677  8.84587   30.33217 1.000 75.51478  ? 93   PHE A HZ    1 
ATOM   1418 N  N     . SER A 1 103 ? 22.05758  13.84620  23.84013 1.000 46.41884  ? 94   SER A N     1 
ATOM   1419 C  CA    . SER A 1 103 ? 22.35317  15.03062  23.04140 1.000 47.17600  ? 94   SER A CA    1 
ATOM   1420 C  C     . SER A 1 103 ? 21.09452  15.57594  22.37811 1.000 47.47547  ? 94   SER A C     1 
ATOM   1421 O  O     . SER A 1 103 ? 20.89427  16.79389  22.31758 1.000 54.79397  ? 94   SER A O     1 
ATOM   1422 C  CB    . SER A 1 103 ? 23.41334  14.70305  21.99090 1.000 49.43298  ? 94   SER A CB    1 
ATOM   1423 O  OG    . SER A 1 103 ? 24.63933  14.33880  22.59949 1.000 47.96452  ? 94   SER A OG    1 
ATOM   1424 H  H     . SER A 1 103 ? 22.43726  13.12382  23.56883 1.000 55.74583  ? 94   SER A H     1 
ATOM   1425 H  HA    . SER A 1 103 ? 22.70944  15.71967  23.62378 1.000 56.65441  ? 94   SER A HA    1 
ATOM   1426 H  HB2   . SER A 1 103 ? 23.09980  13.96328  21.44746 1.000 59.36279  ? 94   SER A HB2   1 
ATOM   1427 H  HB3   . SER A 1 103 ? 23.55791  15.48492  21.43532 1.000 59.36279  ? 94   SER A HB3   1 
ATOM   1428 H  HG    . SER A 1 103 ? 24.94719  14.98712  23.03596 1.000 57.60064  ? 94   SER A HG    1 
ATOM   1429 N  N     . LEU A 1 104 ? 20.23328  14.69050  21.87331 1.000 51.32401  ? 95   LEU A N     1 
ATOM   1430 C  CA    . LEU A 1 104 ? 18.99410  15.14079  21.24713 1.000 51.37304  ? 95   LEU A CA    1 
ATOM   1431 C  C     . LEU A 1 104 ? 18.08335  15.81532  22.26493 1.000 52.50516  ? 95   LEU A C     1 
ATOM   1432 O  O     . LEU A 1 104 ? 17.52244  16.88569  22.00231 1.000 55.31112  ? 95   LEU A O     1 
ATOM   1433 C  CB    . LEU A 1 104 ? 18.28181  13.96007  20.58877 1.000 55.34124  ? 95   LEU A CB    1 
ATOM   1434 C  CG    . LEU A 1 104 ? 18.99509  13.34199  19.38709 1.000 52.76126  ? 95   LEU A CG    1 
ATOM   1435 C  CD1   . LEU A 1 104 ? 18.32610  12.03562  18.98941 1.000 57.24713  ? 95   LEU A CD1   1 
ATOM   1436 C  CD2   . LEU A 1 104 ? 19.01909  14.31444  18.21704 1.000 50.66104  ? 95   LEU A CD2   1 
ATOM   1437 H  H     . LEU A 1 104 ? 20.34223  13.83747  21.88112 1.000 61.63203  ? 95   LEU A H     1 
ATOM   1438 H  HA    . LEU A 1 104 ? 19.20871  15.78702  20.55632 1.000 61.69087  ? 95   LEU A HA    1 
ATOM   1439 H  HB2   . LEU A 1 104 ? 18.17629  13.26074  21.25262 1.000 66.45270  ? 95   LEU A HB2   1 
ATOM   1440 H  HB3   . LEU A 1 104 ? 17.41189  14.26205  20.28387 1.000 66.45270  ? 95   LEU A HB3   1 
ATOM   1441 H  HG    . LEU A 1 104 ? 19.91421  13.14844  19.62929 1.000 63.35672  ? 95   LEU A HG    1 
ATOM   1442 H  HD11  . LEU A 1 104 ? 18.78212  11.67016  18.21521 1.000 68.73977  ? 95   LEU A HD11  1 
ATOM   1443 H  HD12  . LEU A 1 104 ? 18.38291  11.41313  19.73115 1.000 68.73977  ? 95   LEU A HD12  1 
ATOM   1444 H  HD13  . LEU A 1 104 ? 17.39644  12.20965  18.77410 1.000 68.73977  ? 95   LEU A HD13  1 
ATOM   1445 H  HD21  . LEU A 1 104 ? 19.40466  13.87070  17.44546 1.000 60.83646  ? 95   LEU A HD21  1 
ATOM   1446 H  HD22  . LEU A 1 104 ? 18.11123  14.59283  18.01911 1.000 60.83646  ? 95   LEU A HD22  1 
ATOM   1447 H  HD23  . LEU A 1 104 ? 19.55634  15.08528  18.45803 1.000 60.83646  ? 95   LEU A HD23  1 
ATOM   1448 N  N     . LEU A 1 105 ? 17.91803  15.19586  23.43619 1.000 53.78255  ? 96   LEU A N     1 
ATOM   1449 C  CA    . LEU A 1 105 ? 17.10551  15.80667  24.48303 1.000 58.37345  ? 96   LEU A CA    1 
ATOM   1450 C  C     . LEU A 1 105 ? 17.67937  17.15438  24.90427 1.000 58.59139  ? 96   LEU A C     1 
ATOM   1451 O  O     . LEU A 1 105 ? 16.93043  18.10753  25.14986 1.000 58.39064  ? 96   LEU A O     1 
ATOM   1452 C  CB    . LEU A 1 105 ? 17.00548  14.86489  25.68330 1.000 58.05913  ? 96   LEU A CB    1 
ATOM   1453 C  CG    . LEU A 1 105 ? 16.09791  15.31522  26.83074 1.000 61.94633  ? 96   LEU A CG    1 
ATOM   1454 C  CD1   . LEU A 1 105 ? 14.66241  15.48805  26.35672 1.000 61.63874  ? 96   LEU A CD1   1 
ATOM   1455 C  CD2   . LEU A 1 105 ? 16.16187  14.32430  27.98065 1.000 56.38388  ? 96   LEU A CD2   1 
ATOM   1456 H  H     . LEU A 1 105 ? 18.26016  14.43485  23.64453 1.000 64.58227  ? 96   LEU A H     1 
ATOM   1457 H  HA    . LEU A 1 105 ? 16.20937  15.95375  24.14214 1.000 70.09135  ? 96   LEU A HA    1 
ATOM   1458 H  HB2   . LEU A 1 105 ? 16.66578  14.01246  25.36887 1.000 69.71418  ? 96   LEU A HB2   1 
ATOM   1459 H  HB3   . LEU A 1 105 ? 17.89572  14.75183  26.05151 1.000 69.71418  ? 96   LEU A HB3   1 
ATOM   1460 H  HG    . LEU A 1 105 ? 16.40929  16.17590  27.15194 1.000 74.37882  ? 96   LEU A HG    1 
ATOM   1461 H  HD11  . LEU A 1 105 ? 14.09885  15.68462  27.12135 1.000 74.00971  ? 96   LEU A HD11  1 
ATOM   1462 H  HD12  . LEU A 1 105 ? 14.62555  16.22034  25.72167 1.000 74.00971  ? 96   LEU A HD12  1 
ATOM   1463 H  HD13  . LEU A 1 105 ? 14.36905  14.66680  25.93200 1.000 74.00971  ? 96   LEU A HD13  1 
ATOM   1464 H  HD21  . LEU A 1 105 ? 15.62837  14.66082  28.71756 1.000 67.70387  ? 96   LEU A HD21  1 
ATOM   1465 H  HD22  . LEU A 1 105 ? 15.81174  13.47054  27.68165 1.000 67.70387  ? 96   LEU A HD22  1 
ATOM   1466 H  HD23  . LEU A 1 105 ? 17.08536  14.22364  28.25979 1.000 67.70387  ? 96   LEU A HD23  1 
ATOM   1467 N  N     . ALA A 1 106 ? 19.00873  17.25350  24.99091 1.000 54.91812  ? 97   ALA A N     1 
ATOM   1468 C  CA    . ALA A 1 106 ? 19.63280  18.51927  25.36147 1.000 59.85282  ? 97   ALA A CA    1 
ATOM   1469 C  C     . ALA A 1 106 ? 19.35474  19.59510  24.31971 1.000 62.14075  ? 97   ALA A C     1 
ATOM   1470 O  O     . ALA A 1 106 ? 19.08488  20.75179  24.66568 1.000 64.54672  ? 97   ALA A O     1 
ATOM   1471 C  CB    . ALA A 1 106 ? 21.13901  18.32921  25.54181 1.000 63.54916  ? 97   ALA A CB    1 
ATOM   1472 H  H     . ALA A 1 106 ? 19.56137  16.61160  24.84209 1.000 65.94496  ? 97   ALA A H     1 
ATOM   1473 H  HA    . ALA A 1 106 ? 19.26217  18.81383  26.20809 1.000 71.86660  ? 97   ALA A HA    1 
ATOM   1474 H  HB1   . ALA A 1 106 ? 21.53628  19.17721  25.79475 1.000 76.30221  ? 97   ALA A HB1   1 
ATOM   1475 H  HB2   . ALA A 1 106 ? 21.29321  17.67110  26.23752 1.000 76.30221  ? 97   ALA A HB2   1 
ATOM   1476 H  HB3   . ALA A 1 106 ? 21.52094  18.02155  24.70493 1.000 76.30221  ? 97   ALA A HB3   1 
ATOM   1477 N  N     . ILE A 1 107 ? 19.42174  19.23562  23.03667 1.000 58.22460  ? 98   ILE A N     1 
ATOM   1478 C  CA    . ILE A 1 107 ? 19.13555  20.20296  21.98110 1.000 60.58468  ? 98   ILE A CA    1 
ATOM   1479 C  C     . ILE A 1 107 ? 17.68918  20.67172  22.07831 1.000 61.84714  ? 98   ILE A C     1 
ATOM   1480 O  O     . ILE A 1 107 ? 17.39852  21.87070  21.99503 1.000 66.13761  ? 98   ILE A O     1 
ATOM   1481 C  CB    . ILE A 1 107 ? 19.44662  19.59674  20.59985 1.000 59.55112  ? 98   ILE A CB    1 
ATOM   1482 C  CG1   . ILE A 1 107 ? 20.95642  19.39004  20.44557 1.000 58.82922  ? 98   ILE A CG1   1 
ATOM   1483 C  CG2   . ILE A 1 107 ? 18.91046  20.49097  19.48793 1.000 58.88940  ? 98   ILE A CG2   1 
ATOM   1484 C  CD1   . ILE A 1 107 ? 21.34795  18.52202  19.26696 1.000 60.23024  ? 98   ILE A CD1   1 
ATOM   1485 H  H     . ILE A 1 107 ? 19.62766  18.44923  22.75597 1.000 69.91274  ? 98   ILE A H     1 
ATOM   1486 H  HA    . ILE A 1 107 ? 19.70897  20.97595  22.10182 1.000 72.74483  ? 98   ILE A HA    1 
ATOM   1487 H  HB    . ILE A 1 107 ? 19.00602  18.73501  20.53503 1.000 71.50455  ? 98   ILE A HB    1 
ATOM   1488 H  HG12  . ILE A 1 107 ? 21.37725  20.25576  20.32581 1.000 70.63828  ? 98   ILE A HG12  1 
ATOM   1489 H  HG13  . ILE A 1 107 ? 21.29487  18.96495  21.24909 1.000 70.63828  ? 98   ILE A HG13  1 
ATOM   1490 H  HG21  . ILE A 1 107 ? 19.27082  20.18995  18.63916 1.000 70.71050  ? 98   ILE A HG21  1 
ATOM   1491 H  HG22  . ILE A 1 107 ? 17.94226  20.43317  19.47538 1.000 70.71050  ? 98   ILE A HG22  1 
ATOM   1492 H  HG23  . ILE A 1 107 ? 19.18504  21.40559  19.65816 1.000 70.71050  ? 98   ILE A HG23  1 
ATOM   1493 H  HD11  . ILE A 1 107 ? 22.30478  18.36506  19.29443 1.000 72.31951  ? 98   ILE A HD11  1 
ATOM   1494 H  HD12  . ILE A 1 107 ? 20.87259  17.67844  19.32433 1.000 72.31951  ? 98   ILE A HD12  1 
ATOM   1495 H  HD13  . ILE A 1 107 ? 21.11131  18.97983  18.44519 1.000 72.31951  ? 98   ILE A HD13  1 
ATOM   1496 N  N     . ALA A 1 108 ? 16.75996  19.73123  22.26393 1.000 63.52581  ? 99   ALA A N     1 
ATOM   1497 C  CA    . ALA A 1 108 ? 15.35188  20.09605  22.38466 1.000 65.64879  ? 99   ALA A CA    1 
ATOM   1498 C  C     . ALA A 1 108 ? 15.13765  21.06278  23.54184 1.000 65.19138  ? 99   ALA A C     1 
ATOM   1499 O  O     . ALA A 1 108 ? 14.43262  22.06883  23.40605 1.000 67.10785  ? 99   ALA A O     1 
ATOM   1500 C  CB    . ALA A 1 108 ? 14.49765  18.84116  22.57000 1.000 65.32916  ? 99   ALA A CB    1 
ATOM   1501 H  H     . ALA A 1 108 ? 16.91785  18.88787  22.32238 1.000 76.27419  ? 99   ALA A H     1 
ATOM   1502 H  HA    . ALA A 1 108 ? 15.07122  20.53336  21.56558 1.000 78.82176  ? 99   ALA A HA    1 
ATOM   1503 H  HB1   . ALA A 1 108 ? 13.56206  19.09633  22.59135 1.000 78.43821  ? 99   ALA A HB1   1 
ATOM   1504 H  HB2   . ALA A 1 108 ? 14.65889  18.23701  21.82844 1.000 78.43821  ? 99   ALA A HB2   1 
ATOM   1505 H  HB3   . ALA A 1 108 ? 14.74280  18.41274  23.40502 1.000 78.43821  ? 99   ALA A HB3   1 
ATOM   1506 N  N     . ILE A 1 109 ? 15.74266  20.77111  24.69413 1.000 67.41326  ? 100  ILE A N     1 
ATOM   1507 C  CA    . ILE A 1 109 ? 15.58988  21.64416  25.85280 1.000 70.20628  ? 100  ILE A CA    1 
ATOM   1508 C  C     . ILE A 1 109 ? 16.23077  22.99992  25.58672 1.000 70.52405  ? 100  ILE A C     1 
ATOM   1509 O  O     . ILE A 1 109 ? 15.67115  24.04636  25.93635 1.000 71.53772  ? 100  ILE A O     1 
ATOM   1510 C  CB    . ILE A 1 109 ? 16.18370  20.97184  27.10444 1.000 66.76819  ? 100  ILE A CB    1 
ATOM   1511 C  CG1   . ILE A 1 109 ? 15.38918  19.71102  27.44937 1.000 69.95218  ? 100  ILE A CG1   1 
ATOM   1512 C  CG2   . ILE A 1 109 ? 16.19185  21.94552  28.27634 1.000 71.54695  ? 100  ILE A CG2   1 
ATOM   1513 C  CD1   . ILE A 1 109 ? 16.06419  18.81103  28.46582 1.000 66.14816  ? 100  ILE A CD1   1 
ATOM   1514 H  H     . ILE A 1 109 ? 16.24022  20.08258  24.82815 1.000 80.93913  ? 100  ILE A H     1 
ATOM   1515 H  HA    . ILE A 1 109 ? 14.64343  21.78829  26.00884 1.000 84.29075  ? 100  ILE A HA    1 
ATOM   1516 H  HB    . ILE A 1 109 ? 17.10013  20.71576  26.91608 1.000 80.16504  ? 100  ILE A HB    1 
ATOM   1517 H  HG12  . ILE A 1 109 ? 14.53049  19.97560  27.81481 1.000 83.98583  ? 100  ILE A HG12  1 
ATOM   1518 H  HG13  . ILE A 1 109 ? 15.25975  19.19430  26.63873 1.000 83.98583  ? 100  ILE A HG13  1 
ATOM   1519 H  HG21  . ILE A 1 109 ? 16.33516  21.44987  29.09774 1.000 85.89955  ? 100  ILE A HG21  1 
ATOM   1520 H  HG22  . ILE A 1 109 ? 16.90747  22.58771  28.14838 1.000 85.89955  ? 100  ILE A HG22  1 
ATOM   1521 H  HG23  . ILE A 1 109 ? 15.33799  22.40441  28.31160 1.000 85.89955  ? 100  ILE A HG23  1 
ATOM   1522 H  HD11  . ILE A 1 109 ? 15.53049  18.00935  28.58147 1.000 79.42101  ? 100  ILE A HD11  1 
ATOM   1523 H  HD12  . ILE A 1 109 ? 16.94793  18.57624  28.14212 1.000 79.42101  ? 100  ILE A HD12  1 
ATOM   1524 H  HD13  . ILE A 1 109 ? 16.13594  19.28513  29.30902 1.000 79.42101  ? 100  ILE A HD13  1 
ATOM   1525 N  N     . ASP A 1 110 ? 17.41397  23.00447  24.96865 1.000 71.19961  ? 101  ASP A N     1 
ATOM   1526 C  CA    . ASP A 1 110 ? 18.07944  24.26338  24.65024 1.000 74.96231  ? 101  ASP A CA    1 
ATOM   1527 C  C     . ASP A 1 110 ? 17.19971  25.14299  23.77126 1.000 73.71223  ? 101  ASP A C     1 
ATOM   1528 O  O     . ASP A 1 110 ? 17.08589  26.35212  24.00437 1.000 75.58710  ? 101  ASP A O     1 
ATOM   1529 C  CB    . ASP A 1 110 ? 19.41574  23.98163  23.96312 1.000 72.68105  ? 101  ASP A CB    1 
ATOM   1530 C  CG    . ASP A 1 110 ? 20.13089  25.24523  23.53887 1.000 74.54203  ? 101  ASP A CG    1 
ATOM   1531 O  OD1   . ASP A 1 110 ? 20.63186  25.96979  24.42311 1.000 83.59171  ? 101  ASP A OD1   1 
ATOM   1532 O  OD2   . ASP A 1 110 ? 20.19430  25.51365  22.32095 1.000 73.79150  ? 101  ASP A OD2   1 
ATOM   1533 H  H     . ASP A 1 110 ? 17.84556  22.30102  24.72681 1.000 85.48275  ? 101  ASP A H     1 
ATOM   1534 H  HA    . ASP A 1 110 ? 18.25708  24.74529  25.47311 1.000 89.99798  ? 101  ASP A HA    1 
ATOM   1535 H  HB2   . ASP A 1 110 ? 19.99273  23.50195  24.57784 1.000 87.26048  ? 101  ASP A HB2   1 
ATOM   1536 H  HB3   . ASP A 1 110 ? 19.25712  23.44571  23.17032 1.000 87.26048  ? 101  ASP A HB3   1 
ATOM   1537 N  N     . ARG A 1 111 ? 16.56533  24.55168  22.75651 1.000 72.46760  ? 102  ARG A N     1 
ATOM   1538 C  CA    . ARG A 1 111 ? 15.69049  25.32181  21.87923 1.000 72.65603  ? 102  ARG A CA    1 
ATOM   1539 C  C     . ARG A 1 111 ? 14.47638  25.83915  22.63923 1.000 74.85823  ? 102  ARG A C     1 
ATOM   1540 O  O     . ARG A 1 111 ? 14.04102  26.97801  22.42889 1.000 74.11656  ? 102  ARG A O     1 
ATOM   1541 C  CB    . ARG A 1 111 ? 15.24696  24.46351  20.69239 1.000 70.47205  ? 102  ARG A CB    1 
ATOM   1542 C  CG    . ARG A 1 111 ? 16.37977  23.71572  19.99815 1.000 71.40000  ? 102  ARG A CG    1 
ATOM   1543 C  CD    . ARG A 1 111 ? 16.67189  24.24407  18.59629 1.000 78.03825  ? 102  ARG A CD    1 
ATOM   1544 N  NE    . ARG A 1 111 ? 16.75596  25.69894  18.53919 1.000 71.47857  ? 102  ARG A NE    1 
ATOM   1545 C  CZ    . ARG A 1 111 ? 17.63478  26.43180  19.20984 1.000 75.90164  ? 102  ARG A CZ    1 
ATOM   1546 N  NH1   . ARG A 1 111 ? 18.49534  25.88345  20.05203 1.000 81.10971  ? 102  ARG A NH1   1 
ATOM   1547 N  NH2   . ARG A 1 111 ? 17.64478  27.75031  19.03721 1.000 80.83127  ? 102  ARG A NH2   1 
ATOM   1548 H  H     . ARG A 1 111 ? 16.62480  23.71690  22.55849 1.000 87.00434  ? 102  ARG A H     1 
ATOM   1549 H  HA    . ARG A 1 111 ? 16.18388  26.08203  21.53349 1.000 87.23045  ? 102  ARG A HA    1 
ATOM   1550 H  HB2   . ARG A 1 111 ? 14.61024  23.80362  21.00868 1.000 84.60968  ? 102  ARG A HB2   1 
ATOM   1551 H  HB3   . ARG A 1 111 ? 14.82833  25.03931  20.03353 1.000 84.60968  ? 102  ARG A HB3   1 
ATOM   1552 H  HG2   . ARG A 1 111 ? 17.18836  23.80708  20.52609 1.000 85.72322  ? 102  ARG A HG2   1 
ATOM   1553 H  HG3   . ARG A 1 111 ? 16.13857  22.77944  19.92003 1.000 85.72322  ? 102  ARG A HG3   1 
ATOM   1554 H  HD2   . ARG A 1 111 ? 17.52061  23.88416  18.29456 1.000 93.68912  ? 102  ARG A HD2   1 
ATOM   1555 H  HD3   . ARG A 1 111 ? 15.96112  23.96269  17.99919 1.000 93.68912  ? 102  ARG A HD3   1 
ATOM   1556 H  HE    . ARG A 1 111 ? 16.19522  26.11144  18.03421 1.000 85.81750  ? 102  ARG A HE    1 
ATOM   1557 H  HH11  . ARG A 1 111 ? 18.49359  25.03232  20.17517 1.000 97.37487  ? 102  ARG A HH11  1 
ATOM   1558 H  HH12  . ARG A 1 111 ? 19.05646  26.37816  20.47630 1.000 97.37487  ? 102  ARG A HH12  1 
ATOM   1559 H  HH21  . ARG A 1 111 ? 17.08605  28.11740  18.49623 1.000 97.04074  ? 102  ARG A HH21  1 
ATOM   1560 H  HH22  . ARG A 1 111 ? 18.20998  28.23591  19.46656 1.000 97.04074  ? 102  ARG A HH22  1 
ATOM   1561 N  N     . TYR A 1 112 ? 13.91489  25.01426  23.52508 1.000 74.04410  ? 103  TYR A N     1 
ATOM   1562 C  CA    . TYR A 1 112 ? 12.76712  25.45319  24.30914 1.000 78.40133  ? 103  TYR A CA    1 
ATOM   1563 C  C     . TYR A 1 112 ? 13.12658  26.64066  25.19215 1.000 80.17879  ? 103  TYR A C     1 
ATOM   1564 O  O     . TYR A 1 112 ? 12.34427  27.58998  25.31770 1.000 80.90795  ? 103  TYR A O     1 
ATOM   1565 C  CB    . TYR A 1 112 ? 12.23609  24.30138  25.15805 1.000 77.69956  ? 103  TYR A CB    1 
ATOM   1566 C  CG    . TYR A 1 112 ? 11.19569  24.73366  26.16063 1.000 79.90217  ? 103  TYR A CG    1 
ATOM   1567 C  CD1   . TYR A 1 112 ? 9.87418   24.91759  25.78122 1.000 82.98802  ? 103  TYR A CD1   1 
ATOM   1568 C  CD2   . TYR A 1 112 ? 11.53407  24.95384  27.48835 1.000 79.29293  ? 103  TYR A CD2   1 
ATOM   1569 C  CE1   . TYR A 1 112 ? 8.91848   25.31237  26.69405 1.000 84.03701  ? 103  TYR A CE1   1 
ATOM   1570 C  CE2   . TYR A 1 112 ? 10.58577  25.34873  28.40970 1.000 82.97627  ? 103  TYR A CE2   1 
ATOM   1571 C  CZ    . TYR A 1 112 ? 9.27881   25.52622  28.00732 1.000 82.37797  ? 103  TYR A CZ    1 
ATOM   1572 O  OH    . TYR A 1 112 ? 8.32797   25.91979  28.92086 1.000 84.69738  ? 103  TYR A OH    1 
ATOM   1573 H  H     . TYR A 1 112 ? 14.17595  24.21092  23.68664 1.000 88.89613  ? 103  TYR A H     1 
ATOM   1574 H  HA    . TYR A 1 112 ? 12.06282  25.72796  23.70138 1.000 94.12481  ? 103  TYR A HA    1 
ATOM   1575 H  HB2   . TYR A 1 112 ? 11.83157  23.64109  24.57385 1.000 93.28269  ? 103  TYR A HB2   1 
ATOM   1576 H  HB3   . TYR A 1 112 ? 12.97441  23.90453  25.64619 1.000 93.28269  ? 103  TYR A HB3   1 
ATOM   1577 H  HD1   . TYR A 1 112 ? 9.62834   24.77223  24.89616 1.000 99.62884  ? 103  TYR A HD1   1 
ATOM   1578 H  HD2   . TYR A 1 112 ? 12.41475  24.83323  27.76176 1.000 95.19473  ? 103  TYR A HD2   1 
ATOM   1579 H  HE1   . TYR A 1 112 ? 8.03648   25.43354  26.42520 1.000 100.88763 ? 103  TYR A HE1   1 
ATOM   1580 H  HE2   . TYR A 1 112 ? 10.82648  25.49420  29.29615 1.000 99.61474  ? 103  TYR A HE2   1 
ATOM   1581 H  HH    . TYR A 1 112 ? 8.65444   25.91654  29.69482 1.000 101.68008 ? 103  TYR A HH    1 
ATOM   1582 N  N     . ILE A 1 113 ? 14.30353  26.60552  25.81813 1.000 79.70044  ? 104  ILE A N     1 
ATOM   1583 C  CA    . ILE A 1 113 ? 14.73903  27.74275  26.62298 1.000 81.38311  ? 104  ILE A CA    1 
ATOM   1584 C  C     . ILE A 1 113 ? 14.93671  28.96751  25.73953 1.000 84.73964  ? 104  ILE A C     1 
ATOM   1585 O  O     . ILE A 1 113 ? 14.63205  30.09770  26.14058 1.000 88.70585  ? 104  ILE A O     1 
ATOM   1586 C  CB    . ILE A 1 113 ? 16.02174  27.38681  27.39668 1.000 85.72620  ? 104  ILE A CB    1 
ATOM   1587 C  CG1   . ILE A 1 113 ? 15.74871  26.25446  28.38924 1.000 84.01187  ? 104  ILE A CG1   1 
ATOM   1588 C  CG2   . ILE A 1 113 ? 16.55626  28.60278  28.14243 1.000 88.34095  ? 104  ILE A CG2   1 
ATOM   1589 C  CD1   . ILE A 1 113 ? 16.92630  25.32771  28.59390 1.000 84.50945  ? 104  ILE A CD1   1 
ATOM   1590 H  H     . ILE A 1 113 ? 14.85702  25.94778  25.79297 1.000 95.68374  ? 104  ILE A H     1 
ATOM   1591 H  HA    . ILE A 1 113 ? 14.04743  27.94916  27.27104 1.000 97.70295  ? 104  ILE A HA    1 
ATOM   1592 H  HB    . ILE A 1 113 ? 16.68606  27.09421  26.75328 1.000 102.91465 ? 104  ILE A HB    1 
ATOM   1593 H  HG12  . ILE A 1 113 ? 15.52321  26.64135  29.24968 1.000 100.85746 ? 104  ILE A HG12  1 
ATOM   1594 H  HG13  . ILE A 1 113 ? 15.00717  25.72289  28.05991 1.000 100.85746 ? 104  ILE A HG13  1 
ATOM   1595 H  HG21  . ILE A 1 113 ? 17.34397  28.34352  28.64563 1.000 106.05236 ? 104  ILE A HG21  1 
ATOM   1596 H  HG22  . ILE A 1 113 ? 16.78641  29.29159  27.49942 1.000 106.05236 ? 104  ILE A HG22  1 
ATOM   1597 H  HG23  . ILE A 1 113 ? 15.87085  28.92948  28.74607 1.000 106.05236 ? 104  ILE A HG23  1 
ATOM   1598 H  HD11  . ILE A 1 113 ? 16.70799  24.68872  29.29027 1.000 101.45455 ? 104  ILE A HD11  1 
ATOM   1599 H  HD12  . ILE A 1 113 ? 17.10962  24.86180  27.76310 1.000 101.45455 ? 104  ILE A HD12  1 
ATOM   1600 H  HD13  . ILE A 1 113 ? 17.69893  25.85208  28.85652 1.000 101.45455 ? 104  ILE A HD13  1 
ATOM   1601 N  N     . ALA A 1 114 ? 15.44075  28.76369  24.51956 1.000 82.43592  ? 105  ALA A N     1 
ATOM   1602 C  CA    . ALA A 1 114 ? 15.72533  29.89253  23.63916 1.000 83.73643  ? 105  ALA A CA    1 
ATOM   1603 C  C     . ALA A 1 114 ? 14.45734  30.63905  23.24589 1.000 84.85792  ? 105  ALA A C     1 
ATOM   1604 O  O     . ALA A 1 114 ? 14.48995  31.86272  23.06943 1.000 89.95000  ? 105  ALA A O     1 
ATOM   1605 C  CB    . ALA A 1 114 ? 16.46121  29.40562  22.38952 1.000 82.63310  ? 105  ALA A CB    1 
ATOM   1606 H  H     . ALA A 1 114 ? 15.62354  27.99304  24.18446 1.000 98.96632  ? 105  ALA A H     1 
ATOM   1607 H  HA    . ALA A 1 114 ? 16.30198  30.51469  24.10960 1.000 100.52693 ? 105  ALA A HA    1 
ATOM   1608 H  HB1   . ALA A 1 114 ? 16.63925  30.16443  21.81210 1.000 99.20294  ? 105  ALA A HB1   1 
ATOM   1609 H  HB2   . ALA A 1 114 ? 17.29603  28.99003  22.65645 1.000 99.20294  ? 105  ALA A HB2   1 
ATOM   1610 H  HB3   . ALA A 1 114 ? 15.90408  28.76085  21.92608 1.000 99.20294  ? 105  ALA A HB3   1 
ATOM   1611 N  N     . ILE A 1 115 ? 13.33961  29.93275  23.09972 1.000 78.62637  ? 106  ILE A N     1 
ATOM   1612 C  CA    . ILE A 1 115 ? 12.07788  30.54116  22.69384 1.000 78.52984  ? 106  ILE A CA    1 
ATOM   1613 C  C     . ILE A 1 115 ? 11.19646  30.86896  23.89290 1.000 85.48823  ? 106  ILE A C     1 
ATOM   1614 O  O     . ILE A 1 115 ? 10.49482  31.88039  23.88961 1.000 82.49853  ? 106  ILE A O     1 
ATOM   1615 C  CB    . ILE A 1 115 ? 11.33544  29.62071  21.69859 1.000 79.66207  ? 106  ILE A CB    1 
ATOM   1616 C  CG1   . ILE A 1 115 ? 12.20626  29.38274  20.46153 1.000 80.09878  ? 106  ILE A CG1   1 
ATOM   1617 C  CG2   . ILE A 1 115 ? 9.98446   30.22230  21.30540 1.000 79.99340  ? 106  ILE A CG2   1 
ATOM   1618 C  CD1   . ILE A 1 115 ? 11.50493  28.67334  19.32085 1.000 77.49506  ? 106  ILE A CD1   1 
ATOM   1619 H  H     . ILE A 1 115 ? 13.28655  29.08469  23.23236 1.000 94.39486  ? 106  ILE A H     1 
ATOM   1620 H  HA    . ILE A 1 115 ? 12.27487  31.37619  22.24127 1.000 94.27902  ? 106  ILE A HA    1 
ATOM   1621 H  HB    . ILE A 1 115 ? 11.16770  28.76889  22.13120 1.000 95.63770  ? 106  ILE A HB    1 
ATOM   1622 H  HG12  . ILE A 1 115 ? 12.51012  30.24164  20.12856 1.000 96.16175  ? 106  ILE A HG12  1 
ATOM   1623 H  HG13  . ILE A 1 115 ? 12.96693  28.83914  20.71993 1.000 96.16175  ? 106  ILE A HG13  1 
ATOM   1624 H  HG21  . ILE A 1 115 ? 9.54179   29.62456  20.68278 1.000 96.03530  ? 106  ILE A HG21  1 
ATOM   1625 H  HG22  . ILE A 1 115 ? 9.44260   30.32986  22.10272 1.000 96.03530  ? 106  ILE A HG22  1 
ATOM   1626 H  HG23  . ILE A 1 115 ? 10.13257  31.08493  20.88727 1.000 96.03530  ? 106  ILE A HG23  1 
ATOM   1627 H  HD11  . ILE A 1 115 ? 12.17113  28.33278  18.70352 1.000 93.03729  ? 106  ILE A HD11  1 
ATOM   1628 H  HD12  . ILE A 1 115 ? 10.98086  27.94013  19.67953 1.000 93.03729  ? 106  ILE A HD12  1 
ATOM   1629 H  HD13  . ILE A 1 115 ? 10.92433  29.30359  18.86634 1.000 93.03729  ? 106  ILE A HD13  1 
ATOM   1630 N  N     . ALA A 1 116 ? 11.19992  30.01710  24.91985 1.000 87.56211  ? 107  ALA A N     1 
ATOM   1631 C  CA    . ALA A 1 116 ? 10.38663  30.29685  26.09868 1.000 90.15727  ? 107  ALA A CA    1 
ATOM   1632 C  C     . ALA A 1 116 ? 10.92711  31.50388  26.85553 1.000 88.71513  ? 107  ALA A C     1 
ATOM   1633 O  O     . ALA A 1 116 ? 10.17687  32.43255  27.17741 1.000 88.45276  ? 107  ALA A O     1 
ATOM   1634 C  CB    . ALA A 1 116 ? 10.32703  29.06797  27.00679 1.000 85.75803  ? 107  ALA A CB    1 
ATOM   1635 H  H     . ALA A 1 116 ? 11.65412  29.28775  24.95676 1.000 105.11775 ? 107  ALA A H     1 
ATOM   1636 H  HA    . ALA A 1 116 ? 9.48104   30.49681  25.81437 1.000 108.23194 ? 107  ALA A HA    1 
ATOM   1637 H  HB1   . ALA A 1 116 ? 9.77966   29.27349  27.78077 1.000 102.95285 ? 107  ALA A HB1   1 
ATOM   1638 H  HB2   . ALA A 1 116 ? 9.93791   28.32913  26.51323 1.000 102.95285 ? 107  ALA A HB2   1 
ATOM   1639 H  HB3   . ALA A 1 116 ? 11.22662  28.83992  27.28901 1.000 102.95285 ? 107  ALA A HB3   1 
ATOM   1640 N  N     . ILE A 1 117 ? 12.22662  31.51542  27.13989 1.000 85.99164  ? 108  ILE A N     1 
ATOM   1641 C  CA    . ILE A 1 117 ? 12.84852  32.65965  27.80216 1.000 90.37413  ? 108  ILE A CA    1 
ATOM   1642 C  C     . ILE A 1 117 ? 14.02994  33.13633  26.96084 1.000 93.51676  ? 108  ILE A C     1 
ATOM   1643 O  O     . ILE A 1 117 ? 15.16805  32.69059  27.15967 1.000 96.69149  ? 108  ILE A O     1 
ATOM   1644 C  CB    . ILE A 1 117 ? 13.24908  32.32106  29.24994 1.000 90.84683  ? 108  ILE A CB    1 
ATOM   1645 C  CG1   . ILE A 1 117 ? 14.43383  31.35526  29.33375 1.000 96.71502  ? 108  ILE A CG1   1 
ATOM   1646 C  CG2   . ILE A 1 117 ? 12.06746  31.70238  29.98948 1.000 94.20457  ? 108  ILE A CG2   1 
ATOM   1647 C  CD1   . ILE A 1 117 ? 15.72804  32.02514  29.79130 1.000 96.63823  ? 108  ILE A CD1   1 
ATOM   1648 H  H     . ILE A 1 117 ? 12.76934  30.87311  26.95962 1.000 103.23319 ? 108  ILE A H     1 
ATOM   1649 H  HA    . ILE A 1 117 ? 12.21325  33.39139  27.84568 1.000 108.49217 ? 108  ILE A HA    1 
ATOM   1650 H  HB    . ILE A 1 117 ? 13.51696  33.15945  29.65767 1.000 109.05941 ? 108  ILE A HB    1 
ATOM   1651 H  HG12  . ILE A 1 117 ? 14.22153  30.65270  29.96797 1.000 116.10124 ? 108  ILE A HG12  1 
ATOM   1652 H  HG13  . ILE A 1 117 ? 14.59006  30.97355  28.45580 1.000 116.10124 ? 108  ILE A HG13  1 
ATOM   1653 H  HG21  . ILE A 1 117 ? 12.30356  31.58948  30.92351 1.000 113.08870 ? 108  ILE A HG21  1 
ATOM   1654 H  HG22  . ILE A 1 117 ? 11.30166  32.29253  29.91087 1.000 113.08870 ? 108  ILE A HG22  1 
ATOM   1655 H  HG23  . ILE A 1 117 ? 11.86313  30.84079  29.59348 1.000 113.08870 ? 108  ILE A HG23  1 
ATOM   1656 H  HD11  . ILE A 1 117 ? 16.47241  31.42963  29.61191 1.000 116.00909 ? 108  ILE A HD11  1 
ATOM   1657 H  HD12  . ILE A 1 117 ? 15.84359  32.85538  29.30319 1.000 116.00909 ? 108  ILE A HD12  1 
ATOM   1658 H  HD13  . ILE A 1 117 ? 15.67088  32.20591  30.74259 1.000 116.00909 ? 108  ILE A HD13  1 
ATOM   1659 N  N     . PRO A 1 118 ? 13.80637  34.01851  25.98458 1.000 89.70201  ? 109  PRO A N     1 
ATOM   1660 C  CA    . PRO A 1 118 ? 14.94696  34.58750  25.24960 1.000 88.12449  ? 109  PRO A CA    1 
ATOM   1661 C  C     . PRO A 1 118 ? 15.79450  35.52922  26.08650 1.000 95.08548  ? 109  PRO A C     1 
ATOM   1662 O  O     . PRO A 1 118 ? 16.96568  35.74311  25.75024 1.000 95.45671  ? 109  PRO A O     1 
ATOM   1663 C  CB    . PRO A 1 118 ? 14.28317  35.32887  24.07916 1.000 93.74112  ? 109  PRO A CB    1 
ATOM   1664 C  CG    . PRO A 1 118 ? 12.92096  34.71915  23.95202 1.000 92.18995  ? 109  PRO A CG    1 
ATOM   1665 C  CD    . PRO A 1 118 ? 12.51810  34.33719  25.34444 1.000 87.98996  ? 109  PRO A CD    1 
ATOM   1666 H  HA    . PRO A 1 118 ? 15.50559  33.87611  24.89924 1.000 105.79261 ? 109  PRO A HA    1 
ATOM   1667 H  HB2   . PRO A 1 118 ? 14.22169  36.27562  24.28112 1.000 112.53256 ? 109  PRO A HB2   1 
ATOM   1668 H  HB3   . PRO A 1 118 ? 14.79969  35.19532  23.26905 1.000 112.53256 ? 109  PRO A HB3   1 
ATOM   1669 H  HG2   . PRO A 1 118 ? 12.30388  35.36914  23.58104 1.000 110.67116 ? 109  PRO A HG2   1 
ATOM   1670 H  HG3   . PRO A 1 118 ? 12.96352  33.93752  23.37918 1.000 110.67116 ? 109  PRO A HG3   1 
ATOM   1671 H  HD2   . PRO A 1 118 ? 12.08124  35.07729  25.79422 1.000 105.63117 ? 109  PRO A HD2   1 
ATOM   1672 H  HD3   . PRO A 1 118 ? 11.93416  33.56270  25.33620 1.000 105.63117 ? 109  PRO A HD3   1 
ATOM   1673 N  N     . LEU A 1 119 ? 15.24749  36.08921  27.16778 1.000 94.29198  ? 110  LEU A N     1 
ATOM   1674 C  CA    . LEU A 1 119 ? 15.98142  37.08475  27.94224 1.000 97.39322  ? 110  LEU A CA    1 
ATOM   1675 C  C     . LEU A 1 119 ? 17.14106  36.45262  28.70269 1.000 99.25162  ? 110  LEU A C     1 
ATOM   1676 O  O     . LEU A 1 119 ? 18.28965  36.89521  28.58300 1.000 97.34751  ? 110  LEU A O     1 
ATOM   1677 C  CB    . LEU A 1 119 ? 15.03191  37.79567  28.90833 1.000 94.76675  ? 110  LEU A CB    1 
ATOM   1678 H  H     . LEU A 1 119 ? 14.46200  35.91108  27.46924 1.000 113.19359 ? 110  LEU A H     1 
ATOM   1679 H  HA    . LEU A 1 119 ? 16.34783  37.74392  27.33220 1.000 116.91508 ? 110  LEU A HA    1 
ATOM   1680 N  N     . ARG A 1 120 ? 16.86061  35.41716  29.49218 1.000 99.91201  ? 111  ARG A N     1 
ATOM   1681 C  CA    . ARG A 1 120 ? 17.85461  34.80384  30.36126 1.000 103.79676 ? 111  ARG A CA    1 
ATOM   1682 C  C     . ARG A 1 120 ? 18.53232  33.59242  29.73124 1.000 102.49259 ? 111  ARG A C     1 
ATOM   1683 O  O     . ARG A 1 120 ? 19.28396  32.89218  30.41742 1.000 100.57663 ? 111  ARG A O     1 
ATOM   1684 C  CB    . ARG A 1 120 ? 17.20895  34.40091  31.68993 1.000 103.20369 ? 111  ARG A CB    1 
ATOM   1685 H  H     . ARG A 1 120 ? 16.08569  35.04736  29.54065 1.000 119.93763 ? 111  ARG A H     1 
ATOM   1686 H  HA    . ARG A 1 120 ? 18.54361  35.46184  30.54351 1.000 124.59933 ? 111  ARG A HA    1 
ATOM   1687 N  N     . TYR A 1 121 ? 18.28844  33.32691  28.44554 1.000 101.10704 ? 112  TYR A N     1 
ATOM   1688 C  CA    . TYR A 1 121 ? 18.93010  32.18470  27.80179 1.000 101.14408 ? 112  TYR A CA    1 
ATOM   1689 C  C     . TYR A 1 121 ? 20.44367  32.35619  27.75622 1.000 100.97991 ? 112  TYR A C     1 
ATOM   1690 O  O     . TYR A 1 121 ? 21.19168  31.38794  27.93692 1.000 96.67480  ? 112  TYR A O     1 
ATOM   1691 C  CB    . TYR A 1 121 ? 18.37298  31.99179  26.39064 1.000 98.31008  ? 112  TYR A CB    1 
ATOM   1692 C  CG    . TYR A 1 121 ? 19.17322  31.02329  25.54381 1.000 94.68608  ? 112  TYR A CG    1 
ATOM   1693 C  CD1   . TYR A 1 121 ? 18.90736  29.66019  25.57079 1.000 92.19492  ? 112  TYR A CD1   1 
ATOM   1694 C  CD2   . TYR A 1 121 ? 20.19438  31.47397  24.71710 1.000 94.79657  ? 112  TYR A CD2   1 
ATOM   1695 C  CE1   . TYR A 1 121 ? 19.63605  28.77393  24.79995 1.000 86.71242  ? 112  TYR A CE1   1 
ATOM   1696 C  CE2   . TYR A 1 121 ? 20.92826  30.59559  23.94270 1.000 95.75567  ? 112  TYR A CE2   1 
ATOM   1697 C  CZ    . TYR A 1 121 ? 20.64498  29.24648  23.98749 1.000 92.58444  ? 112  TYR A CZ    1 
ATOM   1698 O  OH    . TYR A 1 121 ? 21.37375  28.36765  23.21764 1.000 87.34210  ? 112  TYR A OH    1 
ATOM   1699 H  H     . TYR A 1 121 ? 17.76688  33.78332  27.93636 1.000 121.37166 ? 112  TYR A H     1 
ATOM   1700 H  HA    . TYR A 1 121 ? 18.73048  31.38656  28.31562 1.000 121.41611 ? 112  TYR A HA    1 
ATOM   1701 H  HB2   . TYR A 1 121 ? 17.46810  31.64873  26.45710 1.000 118.01531 ? 112  TYR A HB2   1 
ATOM   1702 H  HB3   . TYR A 1 121 ? 18.37027  32.84908  25.93683 1.000 118.01531 ? 112  TYR A HB3   1 
ATOM   1703 H  HD1   . TYR A 1 121 ? 18.22711  29.33818  26.11711 1.000 110.67712 ? 112  TYR A HD1   1 
ATOM   1704 H  HD2   . TYR A 1 121 ? 20.38768  32.38306  24.68414 1.000 113.79910 ? 112  TYR A HD2   1 
ATOM   1705 H  HE1   . TYR A 1 121 ? 19.44687  27.86384  24.82913 1.000 104.09812 ? 112  TYR A HE1   1 
ATOM   1706 H  HE2   . TYR A 1 121 ? 21.60936  30.91240  23.39439 1.000 114.95003 ? 112  TYR A HE2   1 
ATOM   1707 H  HH    . TYR A 1 121 ? 21.08672  27.58553  23.32488 1.000 104.85373 ? 112  TYR A HH    1 
ATOM   1708 N  N     . ASN A 1 122 ? 20.91441  33.58272  27.51497 1.000 105.14434 ? 113  ASN A N     1 
ATOM   1709 C  CA    . ASN A 1 122 ? 22.35092  33.81191  27.40347 1.000 101.02105 ? 113  ASN A CA    1 
ATOM   1710 C  C     . ASN A 1 122 ? 23.07068  33.54488  28.71891 1.000 101.97128 ? 113  ASN A C     1 
ATOM   1711 O  O     . ASN A 1 122 ? 24.24179  33.14860  28.71406 1.000 98.69486  ? 113  ASN A O     1 
ATOM   1712 C  CB    . ASN A 1 122 ? 22.61742  35.24387  26.93781 1.000 98.62955  ? 113  ASN A CB    1 
ATOM   1713 H  H     . ASN A 1 122 ? 20.42971  34.28588  27.41383 1.000 126.21643 ? 113  ASN A H     1 
ATOM   1714 H  HA    . ASN A 1 122 ? 22.71012  33.20409  26.73832 1.000 121.26848 ? 113  ASN A HA    1 
ATOM   1715 N  N     . GLY A 1 123 ? 22.39679  33.75382  29.84834 1.000 98.72733  ? 114  GLY A N     1 
ATOM   1716 C  CA    . GLY A 1 123 ? 23.00900  33.54346  31.14540 1.000 98.40274  ? 114  GLY A CA    1 
ATOM   1717 C  C     . GLY A 1 123 ? 22.69633  32.18304  31.73138 1.000 100.98420 ? 114  GLY A C     1 
ATOM   1718 O  O     . GLY A 1 123 ? 23.50690  31.61128  32.46726 1.000 100.06518 ? 114  GLY A O     1 
ATOM   1719 H  H     . GLY A 1 123 ? 21.57950  34.01901  29.88470 1.000 118.51601 ? 114  GLY A H     1 
ATOM   1720 H  HA2   . GLY A 1 123 ? 23.97195  33.62321  31.06009 1.000 118.12651 ? 114  GLY A HA2   1 
ATOM   1721 H  HA3   . GLY A 1 123 ? 22.68948  34.22042  31.76227 1.000 118.12651 ? 114  GLY A HA3   1 
ATOM   1722 N  N     . LEU A 1 124 ? 21.51321  31.65549  31.41233 1.000 101.63565 ? 115  LEU A N     1 
ATOM   1723 C  CA    . LEU A 1 124 ? 21.13695  30.33314  31.90134 1.000 101.04247 ? 115  LEU A CA    1 
ATOM   1724 C  C     . LEU A 1 124 ? 21.89642  29.23727  31.16427 1.000 105.57926 ? 115  LEU A C     1 
ATOM   1725 O  O     . LEU A 1 124 ? 22.31937  28.24842  31.77487 1.000 102.17112 ? 115  LEU A O     1 
ATOM   1726 C  CB    . LEU A 1 124 ? 19.62720  30.13850  31.75285 1.000 101.68208 ? 115  LEU A CB    1 
ATOM   1727 C  CG    . LEU A 1 124 ? 19.06799  28.72442  31.92168 1.000 98.99429  ? 115  LEU A CG    1 
ATOM   1728 C  CD1   . LEU A 1 124 ? 19.28853  28.20878  33.33399 1.000 101.96929 ? 115  LEU A CD1   1 
ATOM   1729 C  CD2   . LEU A 1 124 ? 17.58618  28.69928  31.56530 1.000 99.27735  ? 115  LEU A CD2   1 
ATOM   1730 H  H     . LEU A 1 124 ? 20.91969  32.03793  30.92133 1.000 122.00599 ? 115  LEU A H     1 
ATOM   1731 H  HA    . LEU A 1 124 ? 21.35904  30.26767  32.84330 1.000 121.29418 ? 115  LEU A HA    1 
ATOM   1732 H  HB2   . LEU A 1 124 ? 19.19144  30.69231  32.41941 1.000 122.06171 ? 115  LEU A HB2   1 
ATOM   1733 H  HB3   . LEU A 1 124 ? 19.37802  30.43267  30.86275 1.000 122.06171 ? 115  LEU A HB3   1 
ATOM   1734 H  HG    . LEU A 1 124 ? 19.54009  28.12849  31.31928 1.000 118.83637 ? 115  LEU A HG    1 
ATOM   1735 H  HD11  . LEU A 1 124 ? 19.03134  27.27430  33.37277 1.000 122.40637 ? 115  LEU A HD11  1 
ATOM   1736 H  HD12  . LEU A 1 124 ? 20.22663  28.30340  33.56184 1.000 122.40637 ? 115  LEU A HD12  1 
ATOM   1737 H  HD13  . LEU A 1 124 ? 18.74512  28.72716  33.94790 1.000 122.40637 ? 115  LEU A HD13  1 
ATOM   1738 H  HD21  . LEU A 1 124 ? 17.32377  27.78608  31.37010 1.000 119.17603 ? 115  LEU A HD21  1 
ATOM   1739 H  HD22  . LEU A 1 124 ? 17.07476  29.03687  32.31722 1.000 119.17603 ? 115  LEU A HD22  1 
ATOM   1740 H  HD23  . LEU A 1 124 ? 17.43901  29.25928  30.78706 1.000 119.17603 ? 115  LEU A HD23  1 
ATOM   1741 N  N     . VAL A 1 125 ? 22.08442  29.39831  29.85816 1.000 104.41694 ? 116  VAL A N     1 
ATOM   1742 C  CA    . VAL A 1 125 ? 22.71641  28.39482  29.01021 1.000 101.40755 ? 116  VAL A CA    1 
ATOM   1743 C  C     . VAL A 1 125 ? 24.04274  28.96399  28.52531 1.000 99.87871  ? 116  VAL A C     1 
ATOM   1744 O  O     . VAL A 1 125 ? 24.07164  29.94408  27.77042 1.000 103.65112 ? 116  VAL A O     1 
ATOM   1745 C  CB    . VAL A 1 125 ? 21.81318  28.00099  27.83332 1.000 100.82491 ? 116  VAL A CB    1 
ATOM   1746 C  CG1   . VAL A 1 125 ? 22.61287  27.27405  26.76542 1.000 99.36644  ? 116  VAL A CG1   1 
ATOM   1747 C  CG2   . VAL A 1 125 ? 20.65603  27.13860  28.32202 1.000 95.17957  ? 116  VAL A CG2   1 
ATOM   1748 H  H     . VAL A 1 125 ? 21.84623  30.10363  29.42758 1.000 125.34354 ? 116  VAL A H     1 
ATOM   1749 H  HA    . VAL A 1 125 ? 22.90374  27.60147  29.53595 1.000 121.73228 ? 116  VAL A HA    1 
ATOM   1750 H  HB    . VAL A 1 125 ? 21.44555  28.80518  27.43453 1.000 121.03310 ? 116  VAL A HB    1 
ATOM   1751 H  HG11  . VAL A 1 125 ? 22.00842  26.73864  26.22795 1.000 119.28294 ? 116  VAL A HG11  1 
ATOM   1752 H  HG12  . VAL A 1 125 ? 23.06122  27.92804  26.20669 1.000 119.28294 ? 116  VAL A HG12  1 
ATOM   1753 H  HG13  . VAL A 1 125 ? 23.26762  26.70218  27.19571 1.000 119.28294 ? 116  VAL A HG13  1 
ATOM   1754 H  HG21  . VAL A 1 125 ? 20.10844  26.88504  27.56258 1.000 114.25870 ? 116  VAL A HG21  1 
ATOM   1755 H  HG22  . VAL A 1 125 ? 21.01276  26.34567  28.75203 1.000 114.25870 ? 116  VAL A HG22  1 
ATOM   1756 H  HG23  . VAL A 1 125 ? 20.12739  27.64886  28.95533 1.000 114.25870 ? 116  VAL A HG23  1 
ATOM   1757 N  N     . THR A 1 126 ? 25.14207  28.34681  28.95382 1.000 98.51862  ? 117  THR A N     1 
ATOM   1758 C  CA    . THR A 1 126 ? 26.48099  28.77169  28.57763 1.000 89.41784  ? 117  THR A CA    1 
ATOM   1759 C  C     . THR A 1 126 ? 27.31380  27.55820  28.18813 1.000 91.90369  ? 117  THR A C     1 
ATOM   1760 O  O     . THR A 1 126 ? 26.96378  26.41316  28.48601 1.000 91.15583  ? 117  THR A O     1 
ATOM   1761 C  CB    . THR A 1 126 ? 27.17585  29.53433  29.71499 1.000 96.41930  ? 117  THR A CB    1 
ATOM   1762 O  OG1   . THR A 1 126 ? 28.57972  29.63343  29.44242 1.000 95.89378  ? 117  THR A OG1   1 
ATOM   1763 C  CG2   . THR A 1 126 ? 26.96820  28.82694  31.03946 1.000 93.02125  ? 117  THR A CG2   1 
ATOM   1764 H  H     . THR A 1 126 ? 25.13409  27.66338  29.47580 1.000 118.26556 ? 117  THR A H     1 
ATOM   1765 H  HA    . THR A 1 126 ? 26.42182  29.35980  27.80852 1.000 107.34462 ? 117  THR A HA    1 
ATOM   1766 H  HB    . THR A 1 126 ? 26.79698  30.42466  29.78331 1.000 115.74638 ? 117  THR A HB    1 
ATOM   1767 H  HG1   . THR A 1 126 ? 28.97771  29.96709  30.10262 1.000 115.11576 ? 117  THR A HG1   1 
ATOM   1768 H  HG21  . THR A 1 126 ? 27.47402  29.27296  31.73667 1.000 111.66872 ? 117  THR A HG21  1 
ATOM   1769 H  HG22  . THR A 1 126 ? 26.02784  28.83717  31.27718 1.000 111.66872 ? 117  THR A HG22  1 
ATOM   1770 H  HG23  . THR A 1 126 ? 27.26640  27.90623  30.97415 1.000 111.66872 ? 117  THR A HG23  1 
ATOM   1771 N  N     . GLY A 1 127 ? 28.43790  27.83063  27.52184 1.000 87.37094  ? 118  GLY A N     1 
ATOM   1772 C  CA    . GLY A 1 127 ? 29.26084  26.75574  26.99762 1.000 86.52678  ? 118  GLY A CA    1 
ATOM   1773 C  C     . GLY A 1 127 ? 29.96485  25.94982  28.06889 1.000 87.26806  ? 118  GLY A C     1 
ATOM   1774 O  O     . GLY A 1 127 ? 30.25324  24.76588  27.86740 1.000 88.02203  ? 118  GLY A O     1 
ATOM   1775 H  H     . GLY A 1 127 ? 28.73814  28.62099  27.36439 1.000 104.88834 ? 118  GLY A H     1 
ATOM   1776 H  HA2   . GLY A 1 127 ? 28.70139  26.15079  26.48580 1.000 103.87536 ? 118  GLY A HA2   1 
ATOM   1777 H  HA3   . GLY A 1 127 ? 29.93661  27.13227  26.41242 1.000 103.87536 ? 118  GLY A HA3   1 
ATOM   1778 N  N     . THR A 1 128 ? 30.25505  26.56797  29.21654 1.000 87.75758  ? 119  THR A N     1 
ATOM   1779 C  CA    . THR A 1 128 ? 30.94670  25.84488  30.27867 1.000 86.39319  ? 119  THR A CA    1 
ATOM   1780 C  C     . THR A 1 128 ? 30.03775  24.78171  30.88304 1.000 85.47694  ? 119  THR A C     1 
ATOM   1781 O  O     . THR A 1 128 ? 30.40898  23.60504  30.97050 1.000 78.63112  ? 119  THR A O     1 
ATOM   1782 C  CB    . THR A 1 128 ? 31.43129  26.80696  31.36817 1.000 90.30791  ? 119  THR A CB    1 
ATOM   1783 O  OG1   . THR A 1 128 ? 30.38189  27.02561  32.32071 1.000 94.15490  ? 119  THR A OG1   1 
ATOM   1784 C  CG2   . THR A 1 128 ? 31.86558  28.14978  30.77948 1.000 90.23544  ? 119  THR A CG2   1 
ATOM   1785 H  H     . THR A 1 128 ? 30.06588  27.38680  29.39916 1.000 105.35232 ? 119  THR A H     1 
ATOM   1786 H  HA    . THR A 1 128 ? 31.72795  25.41441  29.89755 1.000 103.71504 ? 119  THR A HA    1 
ATOM   1787 H  HB    . THR A 1 128 ? 32.20054  26.41463  31.81003 1.000 108.41271 ? 119  THR A HB    1 
ATOM   1788 H  HG1   . THR A 1 128 ? 30.66053  27.50787  32.94950 1.000 113.02910 ? 119  THR A HG1   1 
ATOM   1789 H  HG21  . THR A 1 128 ? 32.32886  28.67274  31.45237 1.000 108.32574 ? 119  THR A HG21  1 
ATOM   1790 H  HG22  . THR A 1 128 ? 32.46136  28.00534  30.02776 1.000 108.32574 ? 119  THR A HG22  1 
ATOM   1791 H  HG23  . THR A 1 128 ? 31.08919  28.64526  30.47514 1.000 108.32574 ? 119  THR A HG23  1 
ATOM   1792 N  N     . ARG A 1 129 ? 28.83817  25.18391  31.31235 1.000 87.88833  ? 120  ARG A N     1 
ATOM   1793 C  CA    . ARG A 1 129 ? 27.85761  24.21023  31.77611 1.000 87.20831  ? 120  ARG A CA    1 
ATOM   1794 C  C     . ARG A 1 129 ? 27.53060  23.19618  30.68866 1.000 82.55302  ? 120  ARG A C     1 
ATOM   1795 O  O     . ARG A 1 129 ? 27.24327  22.03295  30.99061 1.000 82.34868  ? 120  ARG A O     1 
ATOM   1796 C  CB    . ARG A 1 129 ? 26.58323  24.92068  32.23709 1.000 88.68187  ? 120  ARG A CB    1 
ATOM   1797 C  CG    . ARG A 1 129 ? 26.50896  25.16626  33.73909 1.000 91.50084  ? 120  ARG A CG    1 
ATOM   1798 C  CD    . ARG A 1 129 ? 27.27218  26.41205  34.16606 1.000 92.33232  ? 120  ARG A CD    1 
ATOM   1799 N  NE    . ARG A 1 129 ? 26.50732  27.63273  33.93557 1.000 94.21420  ? 120  ARG A NE    1 
ATOM   1800 C  CZ    . ARG A 1 129 ? 25.46683  28.01648  34.66458 1.000 96.77476  ? 120  ARG A CZ    1 
ATOM   1801 N  NH1   . ARG A 1 129 ? 25.00921  27.27638  35.66181 1.000 101.32879 ? 120  ARG A NH1   1 
ATOM   1802 N  NH2   . ARG A 1 129 ? 24.86756  29.16988  34.38317 1.000 100.26004 ? 120  ARG A NH2   1 
ATOM   1803 H  H     . ARG A 1 129 ? 28.57438  26.00186  31.34355 1.000 105.50921 ? 120  ARG A H     1 
ATOM   1804 H  HA    . ARG A 1 129 ? 28.22479  23.73433  32.53743 1.000 104.69319 ? 120  ARG A HA    1 
ATOM   1805 H  HB2   . ARG A 1 129 ? 26.53274  25.78299  31.79576 1.000 106.46145 ? 120  ARG A HB2   1 
ATOM   1806 H  HB3   . ARG A 1 129 ? 25.81907  24.37650  31.99044 1.000 106.46145 ? 120  ARG A HB3   1 
ATOM   1807 H  HG2   . ARG A 1 129 ? 25.58064  25.27994  33.99636 1.000 109.84423 ? 120  ARG A HG2   1 
ATOM   1808 H  HG3   . ARG A 1 129 ? 26.89137  24.40573  34.20412 1.000 109.84423 ? 120  ARG A HG3   1 
ATOM   1809 H  HD2   . ARG A 1 129 ? 27.47109  26.35451  35.11370 1.000 110.84201 ? 120  ARG A HD2   1 
ATOM   1810 H  HD3   . ARG A 1 129 ? 28.09586  26.47095  33.65716 1.000 110.84201 ? 120  ARG A HD3   1 
ATOM   1811 H  HE    . ARG A 1 129 ? 26.74710  28.13833  33.28252 1.000 113.10026 ? 120  ARG A HE    1 
ATOM   1812 H  HH11  . ARG A 1 129 ? 25.38761  26.52747  35.85032 1.000 121.63776 ? 120  ARG A HH11  1 
ATOM   1813 H  HH12  . ARG A 1 129 ? 24.33346  27.54439  36.12129 1.000 121.63776 ? 120  ARG A HH12  1 
ATOM   1814 H  HH21  . ARG A 1 129 ? 25.15515  29.65707  33.73545 1.000 120.35527 ? 120  ARG A HH21  1 
ATOM   1815 H  HH22  . ARG A 1 129 ? 24.19245  29.42854  34.84890 1.000 120.35527 ? 120  ARG A HH22  1 
ATOM   1816 N  N     . ALA A 1 130 ? 27.57678  23.61314  29.42151 1.000 83.99623  ? 121  ALA A N     1 
ATOM   1817 C  CA    . ALA A 1 130 ? 27.29400  22.68993  28.32832 1.000 78.95273  ? 121  ALA A CA    1 
ATOM   1818 C  C     . ALA A 1 130 ? 28.33954  21.58354  28.26747 1.000 75.97783  ? 121  ALA A C     1 
ATOM   1819 O  O     . ALA A 1 130 ? 28.00288  20.40207  28.13134 1.000 75.66502  ? 121  ALA A O     1 
ATOM   1820 C  CB    . ALA A 1 130 ? 27.23118  23.45107  27.00356 1.000 78.97253  ? 121  ALA A CB    1 
ATOM   1821 H  H     . ALA A 1 130 ? 27.76679  24.41440  29.17355 1.000 100.83869 ? 121  ALA A H     1 
ATOM   1822 H  HA    . ALA A 1 130 ? 26.42816  22.27914  28.47826 1.000 94.78649  ? 121  ALA A HA    1 
ATOM   1823 H  HB1   . ALA A 1 130 ? 26.96159  22.83959  26.30049 1.000 94.81026  ? 121  ALA A HB1   1 
ATOM   1824 H  HB2   . ALA A 1 130 ? 26.58465  24.16985  27.08268 1.000 94.81026  ? 121  ALA A HB2   1 
ATOM   1825 H  HB3   . ALA A 1 130 ? 28.10836  23.81535  26.80674 1.000 94.81026  ? 121  ALA A HB3   1 
ATOM   1826 N  N     . ALA A 1 131 ? 29.62104  21.94968  28.37095 1.000 79.22360  ? 122  ALA A N     1 
ATOM   1827 C  CA    . ALA A 1 131 ? 30.67678  20.94209  28.38360 1.000 77.52686  ? 122  ALA A CA    1 
ATOM   1828 C  C     . ALA A 1 131 ? 30.50905  19.98852  29.55882 1.000 78.71425  ? 122  ALA A C     1 
ATOM   1829 O  O     . ALA A 1 131 ? 30.68650  18.77292  29.41378 1.000 75.38245  ? 122  ALA A O     1 
ATOM   1830 C  CB    . ALA A 1 131 ? 32.04812  21.61515  28.43698 1.000 80.16822  ? 122  ALA A CB    1 
ATOM   1831 H  H     . ALA A 1 131 ? 29.89849  22.76125  28.43396 1.000 95.11154  ? 122  ALA A H     1 
ATOM   1832 H  HA    . ALA A 1 131 ? 30.62626  20.42743  27.56294 1.000 93.07545  ? 122  ALA A HA    1 
ATOM   1833 H  HB1   . ALA A 1 131 ? 32.73548  20.93085  28.44997 1.000 96.24508  ? 122  ALA A HB1   1 
ATOM   1834 H  HB2   . ALA A 1 131 ? 32.15507  22.17659  27.65323 1.000 96.24508  ? 122  ALA A HB2   1 
ATOM   1835 H  HB3   . ALA A 1 131 ? 32.10377  22.15519  29.24082 1.000 96.24508  ? 122  ALA A HB3   1 
ATOM   1836 N  N     . GLY A 1 132 ? 30.17367  20.52267  30.73475 1.000 82.88264  ? 123  GLY A N     1 
ATOM   1837 C  CA    . GLY A 1 132 ? 29.93098  19.66246  31.88003 1.000 74.66417  ? 123  GLY A CA    1 
ATOM   1838 C  C     . GLY A 1 132 ? 28.75558  18.72963  31.66518 1.000 75.10095  ? 123  GLY A C     1 
ATOM   1839 O  O     . GLY A 1 132 ? 28.81194  17.54973  32.02265 1.000 73.34994  ? 123  GLY A O     1 
ATOM   1840 H  H     . GLY A 1 132 ? 30.08286  21.36389  30.88872 1.000 99.50239  ? 123  GLY A H     1 
ATOM   1841 H  HA2   . GLY A 1 132 ? 30.72028  19.12497  32.05034 1.000 89.64022  ? 123  GLY A HA2   1 
ATOM   1842 H  HA3   . GLY A 1 132 ? 29.74770  20.21017  32.65934 1.000 89.64022  ? 123  GLY A HA3   1 
ATOM   1843 N  N     . ILE A 1 133 ? 27.67261  19.24548  31.08045 1.000 74.76406  ? 124  ILE A N     1 
ATOM   1844 C  CA    . ILE A 1 133 ? 26.51305  18.40563  30.79762 1.000 73.11088  ? 124  ILE A CA    1 
ATOM   1845 C  C     . ILE A 1 133 ? 26.88928  17.29588  29.82656 1.000 72.44507  ? 124  ILE A C     1 
ATOM   1846 O  O     . ILE A 1 133 ? 26.51356  16.13190  30.01327 1.000 70.73063  ? 124  ILE A O     1 
ATOM   1847 C  CB    . ILE A 1 133 ? 25.35306  19.26191  30.25618 1.000 71.01693  ? 124  ILE A CB    1 
ATOM   1848 C  CG1   . ILE A 1 133 ? 24.80806  20.16845  31.36133 1.000 72.42383  ? 124  ILE A CG1   1 
ATOM   1849 C  CG2   . ILE A 1 133 ? 24.24809  18.37295  29.69741 1.000 73.83021  ? 124  ILE A CG2   1 
ATOM   1850 C  CD1   . ILE A 1 133 ? 23.88508  21.25635  30.86377 1.000 73.20322  ? 124  ILE A CD1   1 
ATOM   1851 H  H     . ILE A 1 133 ? 27.58651  20.06711  30.84149 1.000 89.76009  ? 124  ILE A H     1 
ATOM   1852 H  HA    . ILE A 1 133 ? 26.22003  17.99382  31.62554 1.000 87.77627  ? 124  ILE A HA    1 
ATOM   1853 H  HB    . ILE A 1 133 ? 25.69006  19.81826  29.53659 1.000 85.26353  ? 124  ILE A HB    1 
ATOM   1854 H  HG12  . ILE A 1 133 ? 24.31053  19.62503  31.99225 1.000 86.95181  ? 124  ILE A HG12  1 
ATOM   1855 H  HG13  . ILE A 1 133 ? 25.55462  20.59662  31.80879 1.000 86.95181  ? 124  ILE A HG13  1 
ATOM   1856 H  HG21  . ILE A 1 133 ? 23.45081  18.90830  29.56086 1.000 88.63947  ? 124  ILE A HG21  1 
ATOM   1857 H  HG22  . ILE A 1 133 ? 24.54226  17.99640  28.85327 1.000 88.63947  ? 124  ILE A HG22  1 
ATOM   1858 H  HG23  . ILE A 1 133 ? 24.06441  17.66163  30.33080 1.000 88.63947  ? 124  ILE A HG23  1 
ATOM   1859 H  HD11  . ILE A 1 133 ? 23.70218  21.87218  31.59055 1.000 87.88708  ? 124  ILE A HD11  1 
ATOM   1860 H  HD12  . ILE A 1 133 ? 24.31596  21.72615  30.13266 1.000 87.88708  ? 124  ILE A HD12  1 
ATOM   1861 H  HD13  . ILE A 1 133 ? 23.05836  20.85287  30.55614 1.000 87.88708  ? 124  ILE A HD13  1 
ATOM   1862 N  N     . ILE A 1 134 ? 27.63875  17.63569  28.77590 1.000 72.21636  ? 125  ILE A N     1 
ATOM   1863 C  CA    . ILE A 1 134 ? 28.03505  16.63175  27.79222 1.000 68.96968  ? 125  ILE A CA    1 
ATOM   1864 C  C     . ILE A 1 134 ? 28.87166  15.54403  28.45235 1.000 64.03122  ? 125  ILE A C     1 
ATOM   1865 O  O     . ILE A 1 134 ? 28.66404  14.34815  28.21206 1.000 61.09727  ? 125  ILE A O     1 
ATOM   1866 C  CB    . ILE A 1 134 ? 28.78440  17.30018  26.62349 1.000 68.33304  ? 125  ILE A CB    1 
ATOM   1867 C  CG1   . ILE A 1 134 ? 27.82309  18.18926  25.83048 1.000 65.23711  ? 125  ILE A CG1   1 
ATOM   1868 C  CG2   . ILE A 1 134 ? 29.42189  16.24990  25.72458 1.000 71.83372  ? 125  ILE A CG2   1 
ATOM   1869 C  CD1   . ILE A 1 134 ? 28.49767  19.06715  24.79999 1.000 71.40289  ? 125  ILE A CD1   1 
ATOM   1870 H  H     . ILE A 1 134 ? 27.92632  18.42960  28.61279 1.000 86.70285  ? 125  ILE A H     1 
ATOM   1871 H  HA    . ILE A 1 134 ? 27.23601  16.21425  27.43427 1.000 82.80683  ? 125  ILE A HA    1 
ATOM   1872 H  HB    . ILE A 1 134 ? 29.49373  17.85501  26.98392 1.000 82.04286  ? 125  ILE A HB    1 
ATOM   1873 H  HG12  . ILE A 1 134 ? 27.18931  17.62205  25.36411 1.000 78.32774  ? 125  ILE A HG12  1 
ATOM   1874 H  HG13  . ILE A 1 134 ? 27.35486  18.77002  26.45047 1.000 78.32774  ? 125  ILE A HG13  1 
ATOM   1875 H  HG21  . ILE A 1 134 ? 29.74554  16.67949  24.91736 1.000 86.24368  ? 125  ILE A HG21  1 
ATOM   1876 H  HG22  . ILE A 1 134 ? 30.16041  15.83554  26.19765 1.000 86.24368  ? 125  ILE A HG22  1 
ATOM   1877 H  HG23  . ILE A 1 134 ? 28.75646  15.58105  25.49932 1.000 86.24368  ? 125  ILE A HG23  1 
ATOM   1878 H  HD11  . ILE A 1 134 ? 27.84362  19.68160  24.43178 1.000 85.72669  ? 125  ILE A HD11  1 
ATOM   1879 H  HD12  . ILE A 1 134 ? 29.21342  19.56301  25.22745 1.000 85.72669  ? 125  ILE A HD12  1 
ATOM   1880 H  HD13  . ILE A 1 134 ? 28.85851  18.50675  24.09526 1.000 85.72669  ? 125  ILE A HD13  1 
ATOM   1881 N  N     . ALA A 1 135 ? 29.82825  15.93829  29.29491 1.000 66.41971  ? 126  ALA A N     1 
ATOM   1882 C  CA    . ALA A 1 135 ? 30.63719  14.95481  30.00672 1.000 66.07650  ? 126  ALA A CA    1 
ATOM   1883 C  C     . ALA A 1 135 ? 29.75844  14.02080  30.82814 1.000 65.04683  ? 126  ALA A C     1 
ATOM   1884 O  O     . ALA A 1 135 ? 29.86275  12.79405  30.72049 1.000 60.74820  ? 126  ALA A O     1 
ATOM   1885 C  CB    . ALA A 1 135 ? 31.65261  15.66222  30.90353 1.000 72.44493  ? 126  ALA A CB    1 
ATOM   1886 H  H     . ALA A 1 135 ? 30.02479  16.75735  29.46843 1.000 79.74687  ? 126  ALA A H     1 
ATOM   1887 H  HA    . ALA A 1 135 ? 31.12577  14.42286  29.35924 1.000 79.33502  ? 126  ALA A HA    1 
ATOM   1888 H  HB1   . ALA A 1 135 ? 32.18971  14.99549  31.35949 1.000 86.97714  ? 126  ALA A HB1   1 
ATOM   1889 H  HB2   . ALA A 1 135 ? 32.22038  16.22542  30.35458 1.000 86.97714  ? 126  ALA A HB2   1 
ATOM   1890 H  HB3   . ALA A 1 135 ? 31.17720  16.20426  31.55243 1.000 86.97714  ? 126  ALA A HB3   1 
ATOM   1891 N  N     . ILE A 1 136 ? 28.87941  14.58865  31.65534 1.000 66.85270  ? 127  ILE A N     1 
ATOM   1892 C  CA    . ILE A 1 136 ? 27.99320  13.76800  32.47525 1.000 68.44222  ? 127  ILE A CA    1 
ATOM   1893 C  C     . ILE A 1 136 ? 27.18757  12.81744  31.60038 1.000 62.49932  ? 127  ILE A C     1 
ATOM   1894 O  O     . ILE A 1 136 ? 27.03982  11.63122  31.92006 1.000 63.03255  ? 127  ILE A O     1 
ATOM   1895 C  CB    . ILE A 1 136 ? 27.08228  14.66851  33.33139 1.000 72.72216  ? 127  ILE A CB    1 
ATOM   1896 C  CG1   . ILE A 1 136 ? 27.86859  15.22758  34.51919 1.000 75.24368  ? 127  ILE A CG1   1 
ATOM   1897 C  CG2   . ILE A 1 136 ? 25.86158  13.90026  33.81877 1.000 73.13965  ? 127  ILE A CG2   1 
ATOM   1898 C  CD1   . ILE A 1 136 ? 27.32353  16.53158  35.05848 1.000 77.58123  ? 127  ILE A CD1   1 
ATOM   1899 H  H     . ILE A 1 136 ? 28.77813  15.43641  31.75853 1.000 80.26645  ? 127  ILE A H     1 
ATOM   1900 H  HA    . ILE A 1 136 ? 28.53292  13.22984  33.07523 1.000 82.17388  ? 127  ILE A HA    1 
ATOM   1901 H  HB    . ILE A 1 136 ? 26.77589  15.40470  32.77908 1.000 87.30980  ? 127  ILE A HB    1 
ATOM   1902 H  HG12  . ILE A 1 136 ? 27.84716  14.57839  35.23960 1.000 90.33563  ? 127  ILE A HG12  1 
ATOM   1903 H  HG13  . ILE A 1 136 ? 28.78443  15.38347  34.24021 1.000 90.33563  ? 127  ILE A HG13  1 
ATOM   1904 H  HG21  . ILE A 1 136 ? 25.44166  14.39782  34.53780 1.000 87.81079  ? 127  ILE A HG21  1 
ATOM   1905 H  HG22  . ILE A 1 136 ? 25.23956  13.79532  33.08190 1.000 87.81079  ? 127  ILE A HG22  1 
ATOM   1906 H  HG23  . ILE A 1 136 ? 26.14388  13.02958  34.13990 1.000 87.81079  ? 127  ILE A HG23  1 
ATOM   1907 H  HD11  . ILE A 1 136 ? 27.81917  16.77532  35.85587 1.000 93.14069  ? 127  ILE A HD11  1 
ATOM   1908 H  HD12  . ILE A 1 136 ? 27.42506  17.21989  34.38259 1.000 93.14069  ? 127  ILE A HD12  1 
ATOM   1909 H  HD13  . ILE A 1 136 ? 26.38501  16.41620  35.27472 1.000 93.14069  ? 127  ILE A HD13  1 
ATOM   1910 N  N     . CYS A 1 137 ? 26.66717  13.31466  30.47632 1.000 61.17440  ? 128  CYS A N     1 
ATOM   1911 C  CA    . CYS A 1 137 ? 25.83115  12.47684  29.62257 1.000 60.77672  ? 128  CYS A CA    1 
ATOM   1912 C  C     . CYS A 1 137 ? 26.60903  11.28334  29.07950 1.000 59.75503  ? 128  CYS A C     1 
ATOM   1913 O  O     . CYS A 1 137 ? 26.07245  10.17214  28.99385 1.000 54.21434  ? 128  CYS A O     1 
ATOM   1914 C  CB    . CYS A 1 137 ? 25.25074  13.31136  28.48306 1.000 64.20505  ? 128  CYS A CB    1 
ATOM   1915 S  SG    . CYS A 1 137 ? 24.04023  14.53558  29.03748 1.000 67.82571  ? 128  CYS A SG    1 
ATOM   1916 H  H     . CYS A 1 137 ? 26.78147  14.11828  30.19220 1.000 73.45250  ? 128  CYS A H     1 
ATOM   1917 H  HA    . CYS A 1 137 ? 25.09265  12.13180  30.14836 1.000 72.97528  ? 128  CYS A HA    1 
ATOM   1918 H  HB2   . CYS A 1 137 ? 25.97319  13.78498  28.04187 1.000 77.08928  ? 128  CYS A HB2   1 
ATOM   1919 H  HB3   . CYS A 1 137 ? 24.80941  12.71924  27.85415 1.000 77.08928  ? 128  CYS A HB3   1 
ATOM   1920 H  HG    . CYS A 1 137 ? 23.58274  15.09442  28.07915 1.000 81.43407  ? 128  CYS A HG    1 
ATOM   1921 N  N     . TRP A 1 138 ? 27.87704  11.48693  28.71451 1.000 58.66363  ? 129  TRP A N     1 
ATOM   1922 C  CA    . TRP A 1 138 ? 28.68009  10.37208  28.22197 1.000 55.45720  ? 129  TRP A CA    1 
ATOM   1923 C  C     . TRP A 1 138 ? 28.95446  9.35667   29.32521 1.000 61.62761  ? 129  TRP A C     1 
ATOM   1924 O  O     . TRP A 1 138 ? 28.95256  8.14505   29.07481 1.000 53.47028  ? 129  TRP A O     1 
ATOM   1925 C  CB    . TRP A 1 138 ? 29.98847  10.88854  27.62632 1.000 60.02419  ? 129  TRP A CB    1 
ATOM   1926 C  CG    . TRP A 1 138 ? 29.86129  11.27529  26.18317 1.000 62.50097  ? 129  TRP A CG    1 
ATOM   1927 C  CD1   . TRP A 1 138 ? 29.64547  12.52627  25.68330 1.000 62.03765  ? 129  TRP A CD1   1 
ATOM   1928 C  CD2   . TRP A 1 138 ? 29.93343  10.39842  25.05210 1.000 59.08627  ? 129  TRP A CD2   1 
ATOM   1929 N  NE1   . TRP A 1 138 ? 29.58043  12.48294  24.31169 1.000 63.38291  ? 129  TRP A NE1   1 
ATOM   1930 C  CE2   . TRP A 1 138 ? 29.75418  11.18794  23.89938 1.000 60.48692  ? 129  TRP A CE2   1 
ATOM   1931 C  CE3   . TRP A 1 138 ? 30.13284  9.02232   24.90297 1.000 55.87939  ? 129  TRP A CE3   1 
ATOM   1932 C  CZ2   . TRP A 1 138 ? 29.77237  10.64815  22.61414 1.000 57.71088  ? 129  TRP A CZ2   1 
ATOM   1933 C  CZ3   . TRP A 1 138 ? 30.14845  8.48843   23.62688 1.000 60.55290  ? 129  TRP A CZ3   1 
ATOM   1934 C  CH2   . TRP A 1 138 ? 29.96816  9.29976   22.49961 1.000 56.95213  ? 129  TRP A CH2   1 
ATOM   1935 H  H     . TRP A 1 138 ? 28.28506  12.24346  28.74228 1.000 70.43957  ? 129  TRP A H     1 
ATOM   1936 H  HA    . TRP A 1 138 ? 28.18857  9.92208   27.51712 1.000 66.59185  ? 129  TRP A HA    1 
ATOM   1937 H  HB2   . TRP A 1 138 ? 30.27286  11.67210  28.12237 1.000 72.07225  ? 129  TRP A HB2   1 
ATOM   1938 H  HB3   . TRP A 1 138 ? 30.66085  10.19245  27.69165 1.000 72.07225  ? 129  TRP A HB3   1 
ATOM   1939 H  HD1   . TRP A 1 138 ? 29.55545  13.29655  26.19658 1.000 74.48840  ? 129  TRP A HD1   1 
ATOM   1940 H  HE1   . TRP A 1 138 ? 29.45159  13.15881  23.79574 1.000 76.10271  ? 129  TRP A HE1   1 
ATOM   1941 H  HE3   . TRP A 1 138 ? 30.25255  8.47704   25.64677 1.000 67.09849  ? 129  TRP A HE3   1 
ATOM   1942 H  HZ2   . TRP A 1 138 ? 29.65580  11.18461  21.86346 1.000 69.29627  ? 129  TRP A HZ2   1 
ATOM   1943 H  HZ3   . TRP A 1 138 ? 30.28100  7.57468   23.51558 1.000 72.70669  ? 129  TRP A HZ3   1 
ATOM   1944 H  HH2   . TRP A 1 138 ? 29.98191  8.91266   21.65411 1.000 68.38578  ? 129  TRP A HH2   1 
ATOM   1945 N  N     . VAL A 1 139 ? 29.19063  9.82600   30.55261 1.000 58.93306  ? 130  VAL A N     1 
ATOM   1946 C  CA    . VAL A 1 139 ? 29.40960  8.90172   31.66201 1.000 58.53790  ? 130  VAL A CA    1 
ATOM   1947 C  C     . VAL A 1 139 ? 28.15737  8.06619   31.89745 1.000 57.21686  ? 130  VAL A C     1 
ATOM   1948 O  O     . VAL A 1 139 ? 28.22227  6.83892   32.03824 1.000 56.11207  ? 130  VAL A O     1 
ATOM   1949 C  CB    . VAL A 1 139 ? 29.82262  9.66566   32.93335 1.000 64.09172  ? 130  VAL A CB    1 
ATOM   1950 C  CG1   . VAL A 1 139 ? 30.10985  8.69274   34.06452 1.000 62.68599  ? 130  VAL A CG1   1 
ATOM   1951 C  CG2   . VAL A 1 139 ? 31.04373  10.54014  32.67254 1.000 62.35784  ? 130  VAL A CG2   1 
ATOM   1952 H  H     . VAL A 1 139 ? 29.22822  10.65879  30.76391 1.000 70.76289  ? 130  VAL A H     1 
ATOM   1953 H  HA    . VAL A 1 139 ? 30.13657  8.30408   31.42695 1.000 70.28870  ? 130  VAL A HA    1 
ATOM   1954 H  HB    . VAL A 1 139 ? 29.08872  10.24284  33.19632 1.000 76.95328  ? 130  VAL A HB    1 
ATOM   1955 H  HG11  . VAL A 1 139 ? 30.37095  9.19354   34.85315 1.000 75.26641  ? 130  VAL A HG11  1 
ATOM   1956 H  HG12  . VAL A 1 139 ? 29.30865  8.17825   34.24964 1.000 75.26641  ? 130  VAL A HG12  1 
ATOM   1957 H  HG13  . VAL A 1 139 ? 30.82906  8.09980   33.79609 1.000 75.26641  ? 130  VAL A HG13  1 
ATOM   1958 H  HG21  . VAL A 1 139 ? 31.28207  11.00209  33.49150 1.000 74.87262  ? 130  VAL A HG21  1 
ATOM   1959 H  HG22  . VAL A 1 139 ? 31.77931  9.97746   32.38408 1.000 74.87262  ? 130  VAL A HG22  1 
ATOM   1960 H  HG23  . VAL A 1 139 ? 30.82872  11.18434  31.97996 1.000 74.87262  ? 130  VAL A HG23  1 
ATOM   1961 N  N     . LEU A 1 140 ? 26.99396  8.72073   31.93848 1.000 56.52213  ? 131  LEU A N     1 
ATOM   1962 C  CA    . LEU A 1 140 ? 25.75137  7.98515   32.13976 1.000 57.22065  ? 131  LEU A CA    1 
ATOM   1963 C  C     . LEU A 1 140 ? 25.45082  7.06215   30.96457 1.000 53.65064  ? 131  LEU A C     1 
ATOM   1964 O  O     . LEU A 1 140 ? 24.84368  6.00222   31.15372 1.000 56.32795  ? 131  LEU A O     1 
ATOM   1965 C  CB    . LEU A 1 140 ? 24.59253  8.95642   32.36438 1.000 65.11395  ? 131  LEU A CB    1 
ATOM   1966 C  CG    . LEU A 1 140 ? 24.74576  9.96863   33.50500 1.000 71.11811  ? 131  LEU A CG    1 
ATOM   1967 C  CD1   . LEU A 1 140 ? 23.39412  10.59898  33.83894 1.000 66.52292  ? 131  LEU A CD1   1 
ATOM   1968 C  CD2   . LEU A 1 140 ? 25.36395  9.33985   34.74653 1.000 63.99613  ? 131  LEU A CD2   1 
ATOM   1969 H  H     . LEU A 1 140 ? 26.90154  9.57157   31.85406 1.000 67.86977  ? 131  LEU A H     1 
ATOM   1970 H  HA    . LEU A 1 140 ? 25.83871  7.43852   32.93629 1.000 68.70800  ? 131  LEU A HA    1 
ATOM   1971 H  HB2   . LEU A 1 140 ? 24.46755  9.46602   31.54854 1.000 78.17995  ? 131  LEU A HB2   1 
ATOM   1972 H  HB3   . LEU A 1 140 ? 23.79757  8.43405   32.55433 1.000 78.17995  ? 131  LEU A HB3   1 
ATOM   1973 H  HG    . LEU A 1 140 ? 25.35148  10.66655  33.21019 1.000 85.38495  ? 131  LEU A HG    1 
ATOM   1974 H  HD11  . LEU A 1 140 ? 23.51283  11.23753  34.55940 1.000 79.87072  ? 131  LEU A HD11  1 
ATOM   1975 H  HD12  . LEU A 1 140 ? 23.05234  11.04935  33.05074 1.000 79.87072  ? 131  LEU A HD12  1 
ATOM   1976 H  HD13  . LEU A 1 140 ? 22.77932  9.90082   34.11368 1.000 79.87072  ? 131  LEU A HD13  1 
ATOM   1977 H  HD21  . LEU A 1 140 ? 25.41357  10.00827  35.44770 1.000 76.83857  ? 131  LEU A HD21  1 
ATOM   1978 H  HD22  . LEU A 1 140 ? 24.80877  8.59855   35.03489 1.000 76.83857  ? 131  LEU A HD22  1 
ATOM   1979 H  HD23  . LEU A 1 140 ? 26.25414  9.02152   34.52940 1.000 76.83857  ? 131  LEU A HD23  1 
ATOM   1980 N  N     . SER A 1 141 ? 25.86650  7.43958   29.75159 1.000 52.31967  ? 132  SER A N     1 
ATOM   1981 C  CA    . SER A 1 141 ? 25.66332  6.56593   28.59980 1.000 52.53888  ? 132  SER A CA    1 
ATOM   1982 C  C     . SER A 1 141 ? 26.49288  5.29370   28.72719 1.000 44.56411  ? 132  SER A C     1 
ATOM   1983 O  O     . SER A 1 141 ? 26.01497  4.19834   28.40711 1.000 39.66155  ? 132  SER A O     1 
ATOM   1984 C  CB    . SER A 1 141 ? 26.00779  7.31072   27.30947 1.000 47.66145  ? 132  SER A CB    1 
ATOM   1985 O  OG    . SER A 1 141 ? 25.13188  8.40546   27.10682 1.000 44.75683  ? 132  SER A OG    1 
ATOM   1986 H  H     . SER A 1 141 ? 26.26117  8.18280   29.57425 1.000 62.82682  ? 132  SER A H     1 
ATOM   1987 H  HA    . SER A 1 141 ? 24.72798  6.31279   28.55557 1.000 63.08987  ? 132  SER A HA    1 
ATOM   1988 H  HB2   . SER A 1 141 ? 26.91753  7.64183   27.36983 1.000 57.23696  ? 132  SER A HB2   1 
ATOM   1989 H  HB3   . SER A 1 141 ? 25.92634  6.69906   26.56105 1.000 57.23696  ? 132  SER A HB3   1 
ATOM   1990 H  HG    . SER A 1 141 ? 25.20529  8.95308   27.73953 1.000 53.75141  ? 132  SER A HG    1 
ATOM   1991 N  N     . PHE A 1 142 ? 27.73824  5.41925   29.19497 1.000 49.65981  ? 133  PHE A N     1 
ATOM   1992 C  CA    . PHE A 1 142 ? 28.54495  4.23525   29.47511 1.000 52.76687  ? 133  PHE A CA    1 
ATOM   1993 C  C     . PHE A 1 142 ? 27.91565  3.38832   30.57426 1.000 46.26123  ? 133  PHE A C     1 
ATOM   1994 O  O     . PHE A 1 142 ? 27.94761  2.15404   30.51364 1.000 50.87837  ? 133  PHE A O     1 
ATOM   1995 C  CB    . PHE A 1 142 ? 29.96424  4.64359   29.87253 1.000 48.07584  ? 133  PHE A CB    1 
ATOM   1996 C  CG    . PHE A 1 142 ? 30.90103  4.79541   28.70944 1.000 50.78541  ? 133  PHE A CG    1 
ATOM   1997 C  CD1   . PHE A 1 142 ? 31.45522  3.67965   28.10480 1.000 52.12676  ? 133  PHE A CD1   1 
ATOM   1998 C  CD2   . PHE A 1 142 ? 31.23666  6.05023   28.22710 1.000 51.26441  ? 133  PHE A CD2   1 
ATOM   1999 C  CE1   . PHE A 1 142 ? 32.31971  3.80936   27.03629 1.000 50.90001  ? 133  PHE A CE1   1 
ATOM   2000 C  CE2   . PHE A 1 142 ? 32.10393  6.18712   27.15848 1.000 52.85036  ? 133  PHE A CE2   1 
ATOM   2001 C  CZ    . PHE A 1 142 ? 32.64616  5.06388   26.56271 1.000 53.03552  ? 133  PHE A CZ    1 
ATOM   2002 H  H     . PHE A 1 142 ? 28.13136  6.16712   29.35543 1.000 59.63499  ? 133  PHE A H     1 
ATOM   2003 H  HA    . PHE A 1 142 ? 28.59853  3.70005   28.66791 1.000 63.36346  ? 133  PHE A HA    1 
ATOM   2004 H  HB2   . PHE A 1 142 ? 29.92539  5.49595   30.33393 1.000 57.73422  ? 133  PHE A HB2   1 
ATOM   2005 H  HB3   . PHE A 1 142 ? 30.33058  3.96453   30.46038 1.000 57.73422  ? 133  PHE A HB3   1 
ATOM   2006 H  HD1   . PHE A 1 142 ? 31.24229  2.83199   28.42265 1.000 62.59533  ? 133  PHE A HD1   1 
ATOM   2007 H  HD2   . PHE A 1 142 ? 30.87494  6.80841   28.62613 1.000 61.56051  ? 133  PHE A HD2   1 
ATOM   2008 H  HE1   . PHE A 1 142 ? 32.68176  3.05202   26.63596 1.000 61.12323  ? 133  PHE A HE1   1 
ATOM   2009 H  HE2   . PHE A 1 142 ? 32.32198  7.03370   26.84120 1.000 63.46364  ? 133  PHE A HE2   1 
ATOM   2010 H  HZ    . PHE A 1 142 ? 33.22980  5.15334   25.84420 1.000 63.68584  ? 133  PHE A HZ    1 
ATOM   2011 N  N     . ALA A 1 143 ? 27.34605  4.03411   31.59280 1.000 51.40313  ? 134  ALA A N     1 
ATOM   2012 C  CA    . ALA A 1 143 ? 26.70772  3.29297   32.67546 1.000 57.80197  ? 134  ALA A CA    1 
ATOM   2013 C  C     . ALA A 1 143 ? 25.48750  2.52977   32.17475 1.000 55.23923  ? 134  ALA A C     1 
ATOM   2014 O  O     . ALA A 1 143 ? 25.34042  1.32960   32.43696 1.000 51.15032  ? 134  ALA A O     1 
ATOM   2015 C  CB    . ALA A 1 143 ? 26.31530  4.25004   33.80133 1.000 59.87171  ? 134  ALA A CB    1 
ATOM   2016 H  H     . ALA A 1 143 ? 27.31657  4.88932   31.67851 1.000 61.72697  ? 134  ALA A H     1 
ATOM   2017 H  HA    . ALA A 1 143 ? 27.34154  2.64972   33.02957 1.000 69.40558  ? 134  ALA A HA    1 
ATOM   2018 H  HB1   . ALA A 1 143 ? 25.89419  3.74391   34.51365 1.000 71.88926  ? 134  ALA A HB1   1 
ATOM   2019 H  HB2   . ALA A 1 143 ? 27.11320  4.68941   34.13479 1.000 71.88926  ? 134  ALA A HB2   1 
ATOM   2020 H  HB3   . ALA A 1 143 ? 25.69533  4.90985   33.45321 1.000 71.88926  ? 134  ALA A HB3   1 
ATOM   2021 N  N     . ILE A 1 144 ? 24.59516  3.21571   31.45959 1.000 54.25718  ? 135  ILE A N     1 
ATOM   2022 C  CA    . ILE A 1 144 ? 23.38692  2.57543   30.94601 1.000 53.97147  ? 135  ILE A CA    1 
ATOM   2023 C  C     . ILE A 1 144 ? 23.75271  1.47088   29.96139 1.000 51.24179  ? 135  ILE A C     1 
ATOM   2024 O  O     . ILE A 1 144 ? 23.34779  0.31347   30.11570 1.000 51.19539  ? 135  ILE A O     1 
ATOM   2025 C  CB    . ILE A 1 144 ? 22.46398  3.62126   30.29752 1.000 55.14211  ? 135  ILE A CB    1 
ATOM   2026 C  CG1   . ILE A 1 144 ? 21.85404  4.52280   31.37179 1.000 58.41414  ? 135  ILE A CG1   1 
ATOM   2027 C  CG2   . ILE A 1 144 ? 21.37700  2.94516   29.47052 1.000 54.89809  ? 135  ILE A CG2   1 
ATOM   2028 C  CD1   . ILE A 1 144 ? 21.30148  5.82256   30.83137 1.000 57.64611  ? 135  ILE A CD1   1 
ATOM   2029 H  H     . ILE A 1 144 ? 24.66592  4.04900   31.25904 1.000 65.15183  ? 135  ILE A H     1 
ATOM   2030 H  HA    . ILE A 1 144 ? 22.91104  2.16882   31.68703 1.000 64.80898  ? 135  ILE A HA    1 
ATOM   2031 H  HB    . ILE A 1 144 ? 22.99446  4.17086   29.69967 1.000 66.21375  ? 135  ILE A HB    1 
ATOM   2032 H  HG12  . ILE A 1 144 ? 21.12619  4.04737   31.80203 1.000 70.14018  ? 135  ILE A HG12  1 
ATOM   2033 H  HG13  . ILE A 1 144 ? 22.53927  4.74000   32.02307 1.000 70.14018  ? 135  ILE A HG13  1 
ATOM   2034 H  HG21  . ILE A 1 144 ? 20.69348  3.59817   29.25310 1.000 65.92092  ? 135  ILE A HG21  1 
ATOM   2035 H  HG22  . ILE A 1 144 ? 21.77132  2.59542   28.65622 1.000 65.92092  ? 135  ILE A HG22  1 
ATOM   2036 H  HG23  . ILE A 1 144 ? 20.99048  2.22158   29.98815 1.000 65.92092  ? 135  ILE A HG23  1 
ATOM   2037 H  HD11  . ILE A 1 144 ? 20.89708  6.32056   31.55894 1.000 69.21855  ? 135  ILE A HD11  1 
ATOM   2038 H  HD12  . ILE A 1 144 ? 22.02630  6.33610   30.44174 1.000 69.21855  ? 135  ILE A HD12  1 
ATOM   2039 H  HD13  . ILE A 1 144 ? 20.63489  5.62532   30.15487 1.000 69.21855  ? 135  ILE A HD13  1 
ATOM   2040 N  N     . GLY A 1 145 ? 24.52919  1.81791   28.93340 1.000 51.35531  ? 136  GLY A N     1 
ATOM   2041 C  CA    . GLY A 1 145 ? 24.81179  0.85958   27.87760 1.000 51.79314  ? 136  GLY A CA    1 
ATOM   2042 C  C     . GLY A 1 145 ? 25.50191  -0.39222  28.38145 1.000 49.17827  ? 136  GLY A C     1 
ATOM   2043 O  O     . GLY A 1 145 ? 25.18328  -1.50344  27.94976 1.000 46.10121  ? 136  GLY A O     1 
ATOM   2044 H  H     . GLY A 1 145 ? 24.89623  2.58858   28.82870 1.000 61.66959  ? 136  GLY A H     1 
ATOM   2045 H  HA2   . GLY A 1 145 ? 23.97925  0.59708   27.45466 1.000 62.19498  ? 136  GLY A HA2   1 
ATOM   2046 H  HA3   . GLY A 1 145 ? 25.38513  1.27569   27.21501 1.000 62.19498  ? 136  GLY A HA3   1 
ATOM   2047 N  N     . LEU A 1 146 ? 26.45045  -0.23320  29.30244 1.000 47.82634  ? 137  LEU A N     1 
ATOM   2048 C  CA    . LEU A 1 146 ? 27.24583  -1.34565  29.80392 1.000 53.36782  ? 137  LEU A CA    1 
ATOM   2049 C  C     . LEU A 1 146 ? 26.68255  -1.93381  31.09363 1.000 54.61694  ? 137  LEU A C     1 
ATOM   2050 O  O     . LEU A 1 146 ? 27.37702  -2.69999  31.77144 1.000 55.19086  ? 137  LEU A O     1 
ATOM   2051 C  CB    . LEU A 1 146 ? 28.69465  -0.89526  30.00701 1.000 48.19507  ? 137  LEU A CB    1 
ATOM   2052 C  CG    . LEU A 1 146 ? 29.34638  -0.25512  28.77672 1.000 52.00682  ? 137  LEU A CG    1 
ATOM   2053 C  CD1   . LEU A 1 146 ? 30.77877  0.15879   29.08304 1.000 51.58000  ? 137  LEU A CD1   1 
ATOM   2054 C  CD2   . LEU A 1 146 ? 29.29955  -1.19146  27.56870 1.000 49.20105  ? 137  LEU A CD2   1 
ATOM   2055 H  H     . LEU A 1 146 ? 26.65341  0.52373   29.65664 1.000 57.43483  ? 137  LEU A H     1 
ATOM   2056 H  HA    . LEU A 1 146 ? 27.24710  -2.05464  29.14194 1.000 64.08460  ? 137  LEU A HA    1 
ATOM   2057 H  HB2   . LEU A 1 146 ? 28.71551  -0.24096  30.72280 1.000 57.87730  ? 137  LEU A HB2   1 
ATOM   2058 H  HB3   . LEU A 1 146 ? 29.22594  -1.66965  30.24981 1.000 57.87730  ? 137  LEU A HB3   1 
ATOM   2059 H  HG    . LEU A 1 146 ? 28.84403  0.54150   28.54446 1.000 62.45140  ? 137  LEU A HG    1 
ATOM   2060 H  HD11  . LEU A 1 146 ? 31.17414  0.54269   28.28479 1.000 61.93921  ? 137  LEU A HD11  1 
ATOM   2061 H  HD12  . LEU A 1 146 ? 30.77197  0.81510   29.79726 1.000 61.93921  ? 137  LEU A HD12  1 
ATOM   2062 H  HD13  . LEU A 1 146 ? 31.28175  -0.62380  29.35774 1.000 61.93921  ? 137  LEU A HD13  1 
ATOM   2063 H  HD21  . LEU A 1 146 ? 29.81594  -0.80106  26.84633 1.000 59.08448  ? 137  LEU A HD21  1 
ATOM   2064 H  HD22  . LEU A 1 146 ? 29.67702  -2.04919  27.81915 1.000 59.08448  ? 137  LEU A HD22  1 
ATOM   2065 H  HD23  . LEU A 1 146 ? 28.37667  -1.30428  27.29217 1.000 59.08448  ? 137  LEU A HD23  1 
ATOM   2066 N  N     . THR A 1 147 ? 25.43977  -1.60506  31.43905 1.000 51.04299  ? 138  THR A N     1 
ATOM   2067 C  CA    . THR A 1 147 ? 24.81386  -2.19334  32.61873 1.000 54.32030  ? 138  THR A CA    1 
ATOM   2068 C  C     . THR A 1 147 ? 24.84299  -3.71564  32.61158 1.000 52.35023  ? 138  THR A C     1 
ATOM   2069 O  O     . THR A 1 147 ? 25.03721  -4.30584  33.68807 1.000 53.18023  ? 138  THR A O     1 
ATOM   2070 C  CB    . THR A 1 147 ? 23.36657  -1.69051  32.74053 1.000 54.22583  ? 138  THR A CB    1 
ATOM   2071 O  OG1   . THR A 1 147 ? 23.36642  -0.34290  33.22821 1.000 51.94073  ? 138  THR A OG1   1 
ATOM   2072 C  CG2   . THR A 1 147 ? 22.55548  -2.57735  33.68265 1.000 54.28457  ? 138  THR A CG2   1 
ATOM   2073 H  H     . THR A 1 147 ? 24.94212  -1.04916  31.01135 1.000 61.29480  ? 138  THR A H     1 
ATOM   2074 H  HA    . THR A 1 147 ? 25.30663  -1.89025  33.39732 1.000 65.22758  ? 138  THR A HA    1 
ATOM   2075 H  HB    . THR A 1 147 ? 22.94337  -1.71877  31.86818 1.000 65.11421  ? 138  THR A HB    1 
ATOM   2076 H  HG1   . THR A 1 147 ? 22.57705  -0.07317  33.32688 1.000 62.37209  ? 138  THR A HG1   1 
ATOM   2077 H  HG21  . THR A 1 147 ? 21.74590  -2.11810  33.95571 1.000 65.18470  ? 138  THR A HG21  1 
ATOM   2078 H  HG22  . THR A 1 147 ? 22.31324  -3.40293  33.23471 1.000 65.18470  ? 138  THR A HG22  1 
ATOM   2079 H  HG23  . THR A 1 147 ? 23.07866  -2.78904  34.47155 1.000 65.18470  ? 138  THR A HG23  1 
ATOM   2080 N  N     . PRO A 1 148 ? 24.64309  -4.40367  31.48518 1.000 52.50402  ? 139  PRO A N     1 
ATOM   2081 C  CA    . PRO A 1 148 ? 24.78630  -5.86835  31.50356 1.000 56.45665  ? 139  PRO A CA    1 
ATOM   2082 C  C     . PRO A 1 148 ? 26.12076  -6.33395  32.05816 1.000 52.19725  ? 139  PRO A C     1 
ATOM   2083 O  O     . PRO A 1 148 ? 26.17139  -7.35836  32.74935 1.000 59.49922  ? 139  PRO A O     1 
ATOM   2084 C  CB    . PRO A 1 148 ? 24.61051  -6.24833  30.02666 1.000 52.99357  ? 139  PRO A CB    1 
ATOM   2085 C  CG    . PRO A 1 148 ? 23.71879  -5.18888  29.47971 1.000 45.19725  ? 139  PRO A CG    1 
ATOM   2086 C  CD    . PRO A 1 148 ? 24.10887  -3.91809  30.19856 1.000 52.28526  ? 139  PRO A CD    1 
ATOM   2087 H  HA    . PRO A 1 148 ? 24.06946  -6.26588  32.02221 1.000 67.79119  ? 139  PRO A HA    1 
ATOM   2088 H  HB2   . PRO A 1 148 ? 25.47043  -6.24800  29.57786 1.000 63.63550  ? 139  PRO A HB2   1 
ATOM   2089 H  HB3   . PRO A 1 148 ? 24.19896  -7.12373  29.95450 1.000 63.63550  ? 139  PRO A HB3   1 
ATOM   2090 H  HG2   . PRO A 1 148 ? 23.86078  -5.10153  28.52414 1.000 54.27992  ? 139  PRO A HG2   1 
ATOM   2091 H  HG3   . PRO A 1 148 ? 22.79259  -5.41514  29.65817 1.000 54.27992  ? 139  PRO A HG3   1 
ATOM   2092 H  HD2   . PRO A 1 148 ? 24.78905  -3.43617  29.70257 1.000 62.78553  ? 139  PRO A HD2   1 
ATOM   2093 H  HD3   . PRO A 1 148 ? 23.33535  -3.34983  30.33875 1.000 62.78553  ? 139  PRO A HD3   1 
ATOM   2094 N  N     . MET A 1 149 ? 27.20744  -5.60944  31.77635 1.000 52.86341  ? 140  MET A N     1 
ATOM   2095 C  CA    A MET A 1 149 ? 28.51253  -6.00954  32.28843 0.460 65.29684  ? 140  MET A CA    1 
ATOM   2096 C  CA    B MET A 1 149 ? 28.51551  -6.00007  32.29084 0.540 49.42565  ? 140  MET A CA    1 
ATOM   2097 C  C     . MET A 1 149 ? 28.53685  -6.07459  33.80978 1.000 53.90292  ? 140  MET A C     1 
ATOM   2098 O  O     . MET A 1 149 ? 29.41429  -6.73603  34.37467 1.000 57.06189  ? 140  MET A O     1 
ATOM   2099 C  CB    A MET A 1 149 ? 29.59033  -5.04591  31.78523 0.460 50.97823  ? 140  MET A CB    1 
ATOM   2100 C  CB    B MET A 1 149 ? 29.58737  -5.00580  31.83171 0.540 56.50752  ? 140  MET A CB    1 
ATOM   2101 C  CG    A MET A 1 149 ? 29.68131  -4.97779  30.26711 0.460 57.67898  ? 140  MET A CG    1 
ATOM   2102 C  CG    B MET A 1 149 ? 29.81938  -4.94596  30.33200 0.540 57.63621  ? 140  MET A CG    1 
ATOM   2103 S  SD    A MET A 1 149 ? 31.16475  -4.15109  29.66045 0.460 56.51021  ? 140  MET A SD    1 
ATOM   2104 S  SD    B MET A 1 149 ? 30.67895  -6.38155  29.66301 0.540 57.89994  ? 140  MET A SD    1 
ATOM   2105 C  CE    A MET A 1 149 ? 32.40686  -5.40055  29.98232 0.460 56.83353  ? 140  MET A CE    1 
ATOM   2106 C  CE    B MET A 1 149 ? 32.20526  -6.36504  30.59955 0.540 58.41800  ? 140  MET A CE    1 
ATOM   2107 H  H     . MET A 1 149 ? 27.21421  -4.89640  31.29558 1.000 63.47931  ? 140  MET A H     1 
ATOM   2108 H  HA    . MET A 1 149 ? 28.72230  -6.89070  31.94137 1.000 59.35399  ? 140  MET A HA    1 
ATOM   2109 H  HB2   A MET A 1 149 ? 29.39026  -4.15461  32.11149 0.460 61.21710  ? 140  MET A HB2   1 
ATOM   2110 H  HB2   B MET A 1 149 ? 29.32364  -4.11775  32.11929 0.540 67.85224  ? 140  MET A HB2   1 
ATOM   2111 H  HB3   A MET A 1 149 ? 30.45219  -5.33682  32.12208 0.460 61.21710  ? 140  MET A HB3   1 
ATOM   2112 H  HB3   B MET A 1 149 ? 30.42963  -5.25193  32.24514 0.540 67.85224  ? 140  MET A HB3   1 
ATOM   2113 H  HG2   A MET A 1 149 ? 29.68169  -5.88126  29.91405 0.460 69.25799  ? 140  MET A HG2   1 
ATOM   2114 H  HG2   B MET A 1 149 ? 28.95992  -4.88359  29.88664 0.540 69.20667  ? 140  MET A HG2   1 
ATOM   2115 H  HG3   A MET A 1 149 ? 28.91324  -4.49035  29.93041 0.460 69.25799  ? 140  MET A HG3   1 
ATOM   2116 H  HG3   B MET A 1 149 ? 30.35473  -4.16240  30.13119 0.540 69.20667  ? 140  MET A HG3   1 
ATOM   2117 H  HE1   A MET A 1 149 ? 33.26145  -5.09092  29.64363 0.460 68.24345  ? 140  MET A HE1   1 
ATOM   2118 H  HE1   B MET A 1 149 ? 32.81431  -7.01902  30.22236 0.540 70.14482  ? 140  MET A HE1   1 
ATOM   2119 H  HE2   A MET A 1 149 ? 32.46454  -5.54941  30.93910 0.460 68.24345  ? 140  MET A HE2   1 
ATOM   2120 H  HE2   B MET A 1 149 ? 32.59765  -5.47943  30.54831 0.540 70.14482  ? 140  MET A HE2   1 
ATOM   2121 H  HE3   A MET A 1 149 ? 32.15166  -6.22228  29.53451 0.460 68.24345  ? 140  MET A HE3   1 
ATOM   2122 H  HE3   B MET A 1 149 ? 32.01129  -6.58793  31.52346 0.540 70.14482  ? 140  MET A HE3   1 
ATOM   2123 N  N     . LEU A 1 150 ? 27.59810  -5.41143  34.48209 1.000 54.65521  ? 141  LEU A N     1 
ATOM   2124 C  CA    . LEU A 1 150 ? 27.54945  -5.40601  35.93753 1.000 56.45908  ? 141  LEU A CA    1 
ATOM   2125 C  C     . LEU A 1 150 ? 26.81237  -6.60614  36.51743 1.000 52.46583  ? 141  LEU A C     1 
ATOM   2126 O  O     . LEU A 1 150 ? 26.71326  -6.71195  37.74518 1.000 48.38522  ? 141  LEU A O     1 
ATOM   2127 C  CB    . LEU A 1 150 ? 26.89563  -4.11277  36.43173 1.000 54.68212  ? 141  LEU A CB    1 
ATOM   2128 C  CG    . LEU A 1 150 ? 27.85153  -2.94949  36.70132 1.000 56.71382  ? 141  LEU A CG    1 
ATOM   2129 C  CD1   . LEU A 1 150 ? 28.64025  -2.57329  35.45744 1.000 56.54592  ? 141  LEU A CD1   1 
ATOM   2130 C  CD2   . LEU A 1 150 ? 27.07803  -1.74744  37.23962 1.000 64.84822  ? 141  LEU A CD2   1 
ATOM   2131 H  H     . LEU A 1 150 ? 26.97215  -4.95256  34.11167 1.000 65.62947  ? 141  LEU A H     1 
ATOM   2132 H  HA    . LEU A 1 150 ? 28.45852  -5.43158  36.27491 1.000 67.79411  ? 141  LEU A HA    1 
ATOM   2133 H  HB2   . LEU A 1 150 ? 26.26227  -3.81632  35.75952 1.000 65.66176  ? 141  LEU A HB2   1 
ATOM   2134 H  HB3   . LEU A 1 150 ? 26.43255  -4.30448  37.26222 1.000 65.66176  ? 141  LEU A HB3   1 
ATOM   2135 H  HG    . LEU A 1 150 ? 28.49570  -3.22656  37.37152 1.000 68.09980  ? 141  LEU A HG    1 
ATOM   2136 H  HD11  . LEU A 1 150 ? 29.22288  -1.82656  35.66678 1.000 67.89832  ? 141  LEU A HD11  1 
ATOM   2137 H  HD12  . LEU A 1 150 ? 29.16874  -3.33637  35.17582 1.000 67.89832  ? 141  LEU A HD12  1 
ATOM   2138 H  HD13  . LEU A 1 150 ? 28.02068  -2.32249  34.75449 1.000 67.89832  ? 141  LEU A HD13  1 
ATOM   2139 H  HD21  . LEU A 1 150 ? 27.70679  -1.04844  37.47827 1.000 77.86108  ? 141  LEU A HD21  1 
ATOM   2140 H  HD22  . LEU A 1 150 ? 26.47308  -1.42758  36.55215 1.000 77.86108  ? 141  LEU A HD22  1 
ATOM   2141 H  HD23  . LEU A 1 150 ? 26.57446  -2.02072  38.02232 1.000 77.86108  ? 141  LEU A HD23  1 
ATOM   2142 N  N     . GLY A 1 151 ? 26.29788  -7.50582  35.68156 1.000 50.45737  ? 142  GLY A N     1 
ATOM   2143 C  CA    . GLY A 1 151 ? 25.67057  -8.71171  36.18501 1.000 54.28222  ? 142  GLY A CA    1 
ATOM   2144 C  C     . GLY A 1 151 ? 24.39731  -9.09741  35.46456 1.000 52.29325  ? 142  GLY A C     1 
ATOM   2145 O  O     . GLY A 1 151 ? 23.96777  -10.25287 35.52805 1.000 50.74447  ? 142  GLY A O     1 
ATOM   2146 H  H     . GLY A 1 151 ? 26.30215  -7.43652  34.82436 1.000 60.59207  ? 142  GLY A H     1 
ATOM   2147 H  HA2   . GLY A 1 151 ? 26.29544  -9.44883  36.10071 1.000 65.18187  ? 142  GLY A HA2   1 
ATOM   2148 H  HA3   . GLY A 1 151 ? 25.45577  -8.58545  37.12247 1.000 65.18187  ? 142  GLY A HA3   1 
ATOM   2149 N  N     . TRP A 1 152 ? 23.77933  -8.13947  34.77783 1.000 55.46910  ? 143  TRP A N     1 
ATOM   2150 C  CA    . TRP A 1 152 ? 22.53519  -8.39461  34.05162 1.000 55.83814  ? 143  TRP A CA    1 
ATOM   2151 C  C     . TRP A 1 152 ? 22.87890  -8.90783  32.65267 1.000 55.77080  ? 143  TRP A C     1 
ATOM   2152 O  O     . TRP A 1 152 ? 22.74743  -8.21735  31.64048 1.000 50.76015  ? 143  TRP A O     1 
ATOM   2153 C  CB    . TRP A 1 152 ? 21.67854  -7.13547  34.00443 1.000 54.79417  ? 143  TRP A CB    1 
ATOM   2154 C  CG    . TRP A 1 152 ? 20.22373  -7.39611  33.72197 1.000 51.76598  ? 143  TRP A CG    1 
ATOM   2155 C  CD1   . TRP A 1 152 ? 19.64248  -8.60015  33.44066 1.000 51.32203  ? 143  TRP A CD1   1 
ATOM   2156 C  CD2   . TRP A 1 152 ? 19.16779  -6.42743  33.69895 1.000 50.87775  ? 143  TRP A CD2   1 
ATOM   2157 N  NE1   . TRP A 1 152 ? 18.29269  -8.44006  33.24267 1.000 57.03109  ? 143  TRP A NE1   1 
ATOM   2158 C  CE2   . TRP A 1 152 ? 17.97566  -7.11561  33.39506 1.000 51.03973  ? 143  TRP A CE2   1 
ATOM   2159 C  CE3   . TRP A 1 152 ? 19.11455  -5.04615  33.90627 1.000 50.79926  ? 143  TRP A CE3   1 
ATOM   2160 C  CZ2   . TRP A 1 152 ? 16.74562  -6.46887  33.29198 1.000 48.47310  ? 143  TRP A CZ2   1 
ATOM   2161 C  CZ3   . TRP A 1 152 ? 17.89196  -4.40596  33.80306 1.000 51.60836  ? 143  TRP A CZ3   1 
ATOM   2162 C  CH2   . TRP A 1 152 ? 16.72473  -5.11762  33.50021 1.000 54.18337  ? 143  TRP A CH2   1 
ATOM   2163 H  H     . TRP A 1 152 ? 24.06108  -7.32928  34.71615 1.000 66.60613  ? 143  TRP A H     1 
ATOM   2164 H  HA    . TRP A 1 152 ? 22.02675  -9.07926  34.51383 1.000 67.04898  ? 143  TRP A HA    1 
ATOM   2165 H  HB2   . TRP A 1 152 ? 21.73680  -6.68719  34.86266 1.000 65.79622  ? 143  TRP A HB2   1 
ATOM   2166 H  HB3   . TRP A 1 152 ? 22.01592  -6.55572  33.30374 1.000 65.79622  ? 143  TRP A HB3   1 
ATOM   2167 H  HD1   . TRP A 1 152 ? 20.09527  -9.41093  33.39047 1.000 61.62965  ? 143  TRP A HD1   1 
ATOM   2168 H  HE1   . TRP A 1 152 ? 17.73701  -9.06867  33.05382 1.000 68.48052  ? 143  TRP A HE1   1 
ATOM   2169 H  HE3   . TRP A 1 152 ? 19.88524  -4.56695  34.10949 1.000 61.00233  ? 143  TRP A HE3   1 
ATOM   2170 H  HZ2   . TRP A 1 152 ? 15.96876  -6.93827  33.08934 1.000 58.21093  ? 143  TRP A HZ2   1 
ATOM   2171 H  HZ3   . TRP A 1 152 ? 17.84480  -3.48689  33.93721 1.000 61.97325  ? 143  TRP A HZ3   1 
ATOM   2172 H  HH2   . TRP A 1 152 ? 15.91691  -4.66087  33.43931 1.000 65.06326  ? 143  TRP A HH2   1 
ATOM   2173 N  N     . ASN A 1 153 ? 23.34491  -10.15478 32.61868 1.000 52.62762  ? 144  ASN A N     1 
ATOM   2174 C  CA    . ASN A 1 153 ? 23.73623  -10.79763 31.37345 1.000 53.29047  ? 144  ASN A CA    1 
ATOM   2175 C  C     . ASN A 1 153 ? 23.41615  -12.28395 31.46458 1.000 55.52950  ? 144  ASN A C     1 
ATOM   2176 O  O     . ASN A 1 153 ? 22.93134  -12.77636 32.48796 1.000 57.34437  ? 144  ASN A O     1 
ATOM   2177 C  CB    . ASN A 1 153 ? 25.22217  -10.56983 31.07159 1.000 50.74822  ? 144  ASN A CB    1 
ATOM   2178 C  CG    . ASN A 1 153 ? 26.12412  -11.05072 32.18626 1.000 52.21418  ? 144  ASN A CG    1 
ATOM   2179 O  OD1   . ASN A 1 153 ? 26.25841  -12.25248 32.41952 1.000 55.89786  ? 144  ASN A OD1   1 
ATOM   2180 N  ND2   . ASN A 1 153 ? 26.75951  -10.11232 32.87593 1.000 50.08694  ? 144  ASN A ND2   1 
ATOM   2181 H  H     . ASN A 1 153 ? 23.44369  -10.65227 33.31319 1.000 63.19636  ? 144  ASN A H     1 
ATOM   2182 H  HA    . ASN A 1 153 ? 23.21329  -10.41387 30.65224 1.000 63.99178  ? 144  ASN A HA    1 
ATOM   2183 H  HB2   . ASN A 1 153 ? 25.45873  -11.05290 30.26439 1.000 60.94108  ? 144  ASN A HB2   1 
ATOM   2184 H  HB3   . ASN A 1 153 ? 25.37794  -9.62046  30.94776 1.000 60.94108  ? 144  ASN A HB3   1 
ATOM   2185 H  HD21  . ASN A 1 153 ? 27.28444  -10.33340 33.52027 1.000 60.14755  ? 144  ASN A HD21  1 
ATOM   2186 H  HD22  . ASN A 1 153 ? 26.64647  -9.28291  32.67868 1.000 60.14755  ? 144  ASN A HD22  1 
ATOM   2187 N  N     . ASN A 1 154 ? 23.68987  -12.99960 30.37175 1.000 56.12638  ? 145  ASN A N     1 
ATOM   2188 C  CA    . ASN A 1 154 ? 23.45788  -14.43550 30.29005 1.000 59.00790  ? 145  ASN A CA    1 
ATOM   2189 C  C     . ASN A 1 154 ? 24.75347  -15.23569 30.35042 1.000 58.06325  ? 145  ASN A C     1 
ATOM   2190 O  O     . ASN A 1 154 ? 24.78302  -16.39368 29.92300 1.000 58.54128  ? 145  ASN A O     1 
ATOM   2191 C  CB    . ASN A 1 154 ? 22.69310  -14.77742 29.01194 1.000 61.93157  ? 145  ASN A CB    1 
ATOM   2192 C  CG    . ASN A 1 154 ? 21.29064  -14.21712 29.00997 1.000 60.14209  ? 145  ASN A CG    1 
ATOM   2193 O  OD1   . ASN A 1 154 ? 20.81757  -13.69904 30.02115 1.000 63.65884  ? 145  ASN A OD1   1 
ATOM   2194 N  ND2   . ASN A 1 154 ? 20.61012  -14.32671 27.87499 1.000 61.74483  ? 145  ASN A ND2   1 
ATOM   2195 H  H     . ASN A 1 154 ? 24.01784  -12.66457 29.65079 1.000 67.39487  ? 145  ASN A H     1 
ATOM   2196 H  HA    . ASN A 1 154 ? 22.91246  -14.69712 31.04832 1.000 70.85270  ? 145  ASN A HA    1 
ATOM   2197 H  HB2   . ASN A 1 154 ? 23.16632  -14.40690 28.25057 1.000 74.36110  ? 145  ASN A HB2   1 
ATOM   2198 H  HB3   . ASN A 1 154 ? 22.63207  -15.74180 28.92736 1.000 74.36110  ? 145  ASN A HB3   1 
ATOM   2199 H  HD21  . ASN A 1 154 ? 20.97226  -14.70164 27.19097 1.000 74.13702  ? 145  ASN A HD21  1 
ATOM   2200 H  HD22  . ASN A 1 154 ? 19.80725  -14.02275 27.82395 1.000 74.13702  ? 145  ASN A HD22  1 
ATOM   2201 N  N     . CYS A 1 155 ? 25.82966  -14.64021 30.86718 1.000 55.87672  ? 146  CYS A N     1 
ATOM   2202 C  CA    . CYS A 1 155 ? 27.07658  -15.38200 31.00467 1.000 59.35495  ? 146  CYS A CA    1 
ATOM   2203 C  C     . CYS A 1 155 ? 26.94117  -16.51799 32.00836 1.000 66.19264  ? 146  CYS A C     1 
ATOM   2204 O  O     . CYS A 1 155 ? 27.66298  -17.51658 31.91283 1.000 65.10488  ? 146  CYS A O     1 
ATOM   2205 C  CB    . CYS A 1 155 ? 28.20470  -14.44104 31.42097 1.000 58.12878  ? 146  CYS A CB    1 
ATOM   2206 S  SG    . CYS A 1 155 ? 28.55409  -13.14522 30.21307 1.000 60.47088  ? 146  CYS A SG    1 
ATOM   2207 H  H     . CYS A 1 155 ? 25.86137  -13.82504 31.13938 1.000 67.09529  ? 146  CYS A H     1 
ATOM   2208 H  HA    . CYS A 1 155 ? 27.30863  -15.76485 30.14416 1.000 71.26916  ? 146  CYS A HA    1 
ATOM   2209 H  HB2   . CYS A 1 155 ? 27.95968  -14.01042 32.25489 1.000 69.79775  ? 146  CYS A HB2   1 
ATOM   2210 H  HB3   . CYS A 1 155 ? 29.01520  -14.96019 31.54130 1.000 69.79775  ? 146  CYS A HB3   1 
ATOM   2211 N  N     . GLY A 1 156 ? 26.02502  -16.38850 32.96997 1.000 67.06603  ? 147  GLY A N     1 
ATOM   2212 C  CA    . GLY A 1 156 ? 25.83690  -17.43107 33.96063 1.000 70.53202  ? 147  GLY A CA    1 
ATOM   2213 C  C     . GLY A 1 156 ? 25.19184  -18.68452 33.41483 1.000 67.49679  ? 147  GLY A C     1 
ATOM   2214 O  O     . GLY A 1 156 ? 25.30889  -19.74848 34.03241 1.000 71.56456  ? 147  GLY A O     1 
ATOM   2215 H  H     . GLY A 1 156 ? 25.50629  -15.70915 33.06482 1.000 80.52245  ? 147  GLY A H     1 
ATOM   2216 H  HA2   . GLY A 1 156 ? 26.70046  -17.67448 34.32928 1.000 84.68164  ? 147  GLY A HA2   1 
ATOM   2217 H  HA3   . GLY A 1 156 ? 25.27403  -17.09020 34.67329 1.000 84.68164  ? 147  GLY A HA3   1 
ATOM   2218 N  N     . GLN A 1 157 ? 24.52750  -18.58736 32.26447 1.000 69.33791  ? 148  GLN A N     1 
ATOM   2219 C  CA    . GLN A 1 157 ? 23.85920  -19.72066 31.62636 1.000 68.60905  ? 148  GLN A CA    1 
ATOM   2220 C  C     . GLN A 1 157 ? 24.27263  -19.78728 30.16123 1.000 66.80643  ? 148  GLN A C     1 
ATOM   2221 O  O     . GLN A 1 157 ? 23.45705  -19.55691 29.25998 1.000 74.01867  ? 148  GLN A O     1 
ATOM   2222 C  CB    . GLN A 1 157 ? 22.34043  -19.59988 31.76152 1.000 71.84457  ? 148  GLN A CB    1 
ATOM   2223 H  H     . GLN A 1 157 ? 24.44787  -17.85406 31.82229 1.000 83.24871  ? 148  GLN A H     1 
ATOM   2224 H  HA    . GLN A 1 157 ? 24.14456  -20.54150 32.05727 1.000 82.37408  ? 148  GLN A HA    1 
ATOM   2225 N  N     . PRO A 1 158 ? 25.53677  -20.10319 29.88655 1.000 70.44543  ? 149  PRO A N     1 
ATOM   2226 C  CA    . PRO A 1 158 ? 25.98788  -20.17785 28.49361 1.000 79.43374  ? 149  PRO A CA    1 
ATOM   2227 C  C     . PRO A 1 158 ? 25.31589  -21.31627 27.74355 1.000 87.46306  ? 149  PRO A C     1 
ATOM   2228 O  O     . PRO A 1 158 ? 24.76946  -22.25473 28.32736 1.000 88.46914  ? 149  PRO A O     1 
ATOM   2229 C  CB    . PRO A 1 158 ? 27.49909  -20.41840 28.61177 1.000 78.48838  ? 149  PRO A CB    1 
ATOM   2230 C  CG    . PRO A 1 158 ? 27.85634  -20.02868 30.00117 1.000 80.53397  ? 149  PRO A CG    1 
ATOM   2231 C  CD    . PRO A 1 158 ? 26.64442  -20.32421 30.83196 1.000 74.70088  ? 149  PRO A CD    1 
ATOM   2232 H  HA    . PRO A 1 158 ? 25.82192  -19.33809 28.03736 1.000 95.36371  ? 149  PRO A HA    1 
ATOM   2233 H  HB2   . PRO A 1 158 ? 27.69541  -21.35524 28.45466 1.000 94.22928  ? 149  PRO A HB2   1 
ATOM   2234 H  HB3   . PRO A 1 158 ? 27.97029  -19.86800 27.96683 1.000 94.22928  ? 149  PRO A HB3   1 
ATOM   2235 H  HG2   . PRO A 1 158 ? 28.61575  -20.55136 30.30284 1.000 96.68399  ? 149  PRO A HG2   1 
ATOM   2236 H  HG3   . PRO A 1 158 ? 28.07141  -19.08329 30.03102 1.000 96.68399  ? 149  PRO A HG3   1 
ATOM   2237 H  HD2   . PRO A 1 158 ? 26.65452  -21.24192 31.14597 1.000 89.68428  ? 149  PRO A HD2   1 
ATOM   2238 H  HD3   . PRO A 1 158 ? 26.58381  -19.71639 31.58548 1.000 89.68428  ? 149  PRO A HD3   1 
ATOM   2239 N  N     . LYS A 1 159 ? 25.37318  -21.22058 26.41692 1.000 87.38978  ? 150  LYS A N     1 
ATOM   2240 C  CA    . LYS A 1 159 ? 24.87588  -22.27461 25.53348 1.000 89.07380  ? 150  LYS A CA    1 
ATOM   2241 C  C     . LYS A 1 159 ? 26.04672  -23.20663 25.24788 1.000 89.18564  ? 150  LYS A C     1 
ATOM   2242 O  O     . LYS A 1 159 ? 26.79170  -23.03149 24.28305 1.000 88.26173  ? 150  LYS A O     1 
ATOM   2243 C  CB    . LYS A 1 159 ? 24.28278  -21.67724 24.26471 1.000 88.25976  ? 150  LYS A CB    1 
ATOM   2244 C  CG    . LYS A 1 159 ? 23.25639  -20.58455 24.54000 1.000 83.65162  ? 150  LYS A CG    1 
ATOM   2245 C  CD    . LYS A 1 159 ? 21.98012  -20.77981 23.73936 1.000 79.68237  ? 150  LYS A CD    1 
ATOM   2246 C  CE    . LYS A 1 159 ? 20.84771  -19.93039 24.29700 1.000 84.62252  ? 150  LYS A CE    1 
ATOM   2247 N  NZ    . LYS A 1 159 ? 20.32035  -20.47872 25.57881 1.000 99.01194  ? 150  LYS A NZ    1 
ATOM   2248 H  H     . LYS A 1 159 ? 25.70051  -20.54482 25.99764 1.000 104.91096 ? 150  LYS A H     1 
ATOM   2249 H  HA    . LYS A 1 159 ? 24.17545  -22.78123 25.97352 1.000 106.93178 ? 150  LYS A HA    1 
ATOM   2250 H  HB2   . LYS A 1 159 ? 24.99766  -21.28930 23.73617 1.000 105.95493 ? 150  LYS A HB2   1 
ATOM   2251 H  HB3   . LYS A 1 159 ? 23.84280  -22.38064 23.76218 1.000 105.95493 ? 150  LYS A HB3   1 
ATOM   2252 H  HG2   . LYS A 1 159 ? 23.02598  -20.59407 25.48219 1.000 100.42516 ? 150  LYS A HG2   1 
ATOM   2253 H  HG3   . LYS A 1 159 ? 23.63474  -19.72433 24.29966 1.000 100.42516 ? 150  LYS A HG3   1 
ATOM   2254 H  HD2   . LYS A 1 159 ? 22.13400  -20.51864 22.81794 1.000 95.66205  ? 150  LYS A HD2   1 
ATOM   2255 H  HD3   . LYS A 1 159 ? 21.71301  -21.71143 23.77994 1.000 95.66205  ? 150  LYS A HD3   1 
ATOM   2256 H  HE2   . LYS A 1 159 ? 21.17386  -19.03204 24.46278 1.000 101.59023 ? 150  LYS A HE2   1 
ATOM   2257 H  HE3   . LYS A 1 159 ? 20.12057  -19.90624 23.65546 1.000 101.59023 ? 150  LYS A HE3   1 
ATOM   2258 H  HZ1   . LYS A 1 159 ? 19.67132  -19.95510 25.88975 1.000 118.85754 ? 150  LYS A HZ1   1 
ATOM   2259 H  HZ2   . LYS A 1 159 ? 19.99430  -21.29658 25.44878 1.000 118.85754 ? 150  LYS A HZ2   1 
ATOM   2260 H  HZ3   . LYS A 1 159 ? 20.97233  -20.52042 26.18319 1.000 118.85754 ? 150  LYS A HZ3   1 
ATOM   2261 N  N     . GLU A 1 160 ? 26.21128  -24.21309 26.11075 1.000 99.78663  ? 151  GLU A N     1 
ATOM   2262 C  CA    . GLU A 1 160 ? 27.38935  -25.07178 26.03656 1.000 97.42321  ? 151  GLU A CA    1 
ATOM   2263 C  C     . GLU A 1 160 ? 27.44932  -25.82676 24.71494 1.000 94.04451  ? 151  GLU A C     1 
ATOM   2264 O  O     . GLU A 1 160 ? 28.53030  -25.99857 24.13925 1.000 97.05022  ? 151  GLU A O     1 
ATOM   2265 C  CB    . GLU A 1 160 ? 27.39441  -26.05126 27.21107 1.000 91.32428  ? 151  GLU A CB    1 
ATOM   2266 H  H     . GLU A 1 160 ? 25.66136  -24.41597 26.74007 1.000 119.78717 ? 151  GLU A H     1 
ATOM   2267 H  HA    . GLU A 1 160 ? 28.18210  -24.51619 26.09802 1.000 116.95107 ? 151  GLU A HA    1 
ATOM   2268 N  N     . GLY A 1 161 ? 26.30106  -26.29076 24.22020 1.000 97.22093  ? 152  GLY A N     1 
ATOM   2269 C  CA    . GLY A 1 161 ? 26.29959  -27.04399 22.97604 1.000 100.77178 ? 152  GLY A CA    1 
ATOM   2270 C  C     . GLY A 1 161 ? 26.80618  -26.22790 21.80350 1.000 96.55303  ? 152  GLY A C     1 
ATOM   2271 O  O     . GLY A 1 161 ? 27.66562  -26.67552 21.04025 1.000 99.28398  ? 152  GLY A O     1 
ATOM   2272 H  H     . GLY A 1 161 ? 25.52721  -26.18397 24.57986 1.000 116.70833 ? 152  GLY A H     1 
ATOM   2273 H  HA2   . GLY A 1 161 ? 26.86764  -27.82427 23.07294 1.000 120.96935 ? 152  GLY A HA2   1 
ATOM   2274 H  HA3   . GLY A 1 161 ? 25.39547  -27.33421 22.77798 1.000 120.96935 ? 152  GLY A HA3   1 
ATOM   2275 N  N     . LYS A 1 162 ? 26.27244  -25.01751 21.64186 1.000 95.02146  ? 153  LYS A N     1 
ATOM   2276 C  CA    . LYS A 1 162 ? 26.71331  -24.14455 20.56185 1.000 92.51497  ? 153  LYS A CA    1 
ATOM   2277 C  C     . LYS A 1 162 ? 28.16845  -23.72776 20.72303 1.000 91.54738  ? 153  LYS A C     1 
ATOM   2278 O  O     . LYS A 1 162 ? 28.82158  -23.40236 19.72527 1.000 90.17885  ? 153  LYS A O     1 
ATOM   2279 C  CB    . LYS A 1 162 ? 25.79491  -22.92308 20.49914 1.000 85.48095  ? 153  LYS A CB    1 
ATOM   2280 C  CG    . LYS A 1 162 ? 26.23141  -21.84500 19.52642 1.000 81.07427  ? 153  LYS A CG    1 
ATOM   2281 C  CD    . LYS A 1 162 ? 25.03857  -21.08147 18.95411 1.000 77.28718  ? 153  LYS A CD    1 
ATOM   2282 C  CE    . LYS A 1 162 ? 24.01857  -20.70609 20.02211 1.000 73.15934  ? 153  LYS A CE    1 
ATOM   2283 N  NZ    . LYS A 1 162 ? 22.93792  -19.83922 19.47312 1.000 65.71377  ? 153  LYS A NZ    1 
ATOM   2284 H  H     . LYS A 1 162 ? 25.65797  -24.68206 22.14136 1.000 114.06897 ? 153  LYS A H     1 
ATOM   2285 H  HA    . LYS A 1 162 ? 26.64573  -24.61012 19.71357 1.000 111.06118 ? 153  LYS A HA    1 
ATOM   2286 H  HB2   . LYS A 1 162 ? 24.91048  -23.21707 20.23033 1.000 102.62036 ? 153  LYS A HB2   1 
ATOM   2287 H  HB3   . LYS A 1 162 ? 25.75713  -22.52140 21.38126 1.000 102.62036 ? 153  LYS A HB3   1 
ATOM   2288 H  HG2   . LYS A 1 162 ? 26.80493  -21.21202 19.98611 1.000 97.33234  ? 153  LYS A HG2   1 
ATOM   2289 H  HG3   . LYS A 1 162 ? 26.71205  -22.25388 18.78973 1.000 97.33234  ? 153  LYS A HG3   1 
ATOM   2290 H  HD2   . LYS A 1 162 ? 25.35465  -20.26336 18.53974 1.000 92.78783  ? 153  LYS A HD2   1 
ATOM   2291 H  HD3   . LYS A 1 162 ? 24.59309  -21.63653 18.29505 1.000 92.78783  ? 153  LYS A HD3   1 
ATOM   2292 H  HE2   . LYS A 1 162 ? 23.61157  -21.51323 20.37392 1.000 87.83442  ? 153  LYS A HE2   1 
ATOM   2293 H  HE3   . LYS A 1 162 ? 24.46442  -20.22171 20.73450 1.000 87.83442  ? 153  LYS A HE3   1 
ATOM   2294 H  HZ1   . LYS A 1 162 ? 22.27843  -19.76269 20.06585 1.000 78.89974  ? 153  LYS A HZ1   1 
ATOM   2295 H  HZ2   . LYS A 1 162 ? 23.25957  -19.02922 19.29272 1.000 78.89974  ? 153  LYS A HZ2   1 
ATOM   2296 H  HZ3   . LYS A 1 162 ? 22.61352  -20.19452 18.72437 1.000 78.89974  ? 153  LYS A HZ3   1 
ATOM   2297 N  N     . ALA A 1 163 ? 28.69550  -23.74372 21.94967 1.000 91.62537  ? 154  ALA A N     1 
ATOM   2298 C  CA    . ALA A 1 163 ? 30.11271  -23.46772 22.15496 1.000 88.64520  ? 154  ALA A CA    1 
ATOM   2299 C  C     . ALA A 1 163 ? 30.97297  -24.65770 21.74700 1.000 96.12252  ? 154  ALA A C     1 
ATOM   2300 O  O     . ALA A 1 163 ? 32.04853  -24.47938 21.16429 1.000 95.02302  ? 154  ALA A O     1 
ATOM   2301 C  CB    . ALA A 1 163 ? 30.37049  -23.10293 23.61731 1.000 88.49951  ? 154  ALA A CB    1 
ATOM   2302 H  H     . ALA A 1 163 ? 28.25675  -23.91003 22.67039 1.000 109.99366 ? 154  ALA A H     1 
ATOM   2303 H  HA    . ALA A 1 163 ? 30.36663  -22.70781 21.60819 1.000 106.41745 ? 154  ALA A HA    1 
ATOM   2304 H  HB1   . ALA A 1 163 ? 31.31633  -22.92351 23.73602 1.000 106.24262 ? 154  ALA A HB1   1 
ATOM   2305 H  HB2   . ALA A 1 163 ? 29.85335  -22.31357 23.84176 1.000 106.24262 ? 154  ALA A HB2   1 
ATOM   2306 H  HB3   . ALA A 1 163 ? 30.10151  -23.84569 24.18021 1.000 106.24262 ? 154  ALA A HB3   1 
ATOM   2307 N  N     . HIS A 1 164 ? 30.51389  -25.87690 22.04243 1.000 100.15474 ? 155  HIS A N     1 
ATOM   2308 C  CA    . HIS A 1 164 ? 31.27339  -27.06508 21.66774 1.000 99.27251  ? 155  HIS A CA    1 
ATOM   2309 C  C     . HIS A 1 164 ? 31.20772  -27.31476 20.16496 1.000 97.67548  ? 155  HIS A C     1 
ATOM   2310 O  O     . HIS A 1 164 ? 32.19199  -27.75776 19.56139 1.000 97.39531  ? 155  HIS A O     1 
ATOM   2311 C  CB    . HIS A 1 164 ? 30.75406  -28.28348 22.43296 1.000 101.84735 ? 155  HIS A CB    1 
ATOM   2312 C  CG    . HIS A 1 164 ? 31.28455  -28.39732 23.82910 1.000 102.80094 ? 155  HIS A CG    1 
ATOM   2313 N  ND1   . HIS A 1 164 ? 32.24222  -27.54547 24.33656 1.000 99.11388  ? 155  HIS A ND1   1 
ATOM   2314 C  CD2   . HIS A 1 164 ? 30.99409  -29.27050 24.82267 1.000 104.38858 ? 155  HIS A CD2   1 
ATOM   2315 C  CE1   . HIS A 1 164 ? 32.51651  -27.88706 25.58300 1.000 105.53280 ? 155  HIS A CE1   1 
ATOM   2316 N  NE2   . HIS A 1 164 ? 31.77247  -28.93068 25.90236 1.000 110.61571 ? 155  HIS A NE2   1 
ATOM   2317 H  H     . HIS A 1 164 ? 29.77597  -26.03889 22.45331 1.000 120.22890 ? 155  HIS A H     1 
ATOM   2318 H  HA    . HIS A 1 164 ? 32.20247  -26.92822 21.91063 1.000 119.17022 ? 155  HIS A HA    1 
ATOM   2319 H  HB2   . HIS A 1 164 ? 29.78729  -28.22703 22.48835 1.000 122.26004 ? 155  HIS A HB2   1 
ATOM   2320 H  HB3   . HIS A 1 164 ? 31.01258  -29.08567 21.95278 1.000 122.26004 ? 155  HIS A HB3   1 
ATOM   2321 H  HD2   . HIS A 1 164 ? 30.38207  -29.96953 24.78170 1.000 125.30951 ? 155  HIS A HD2   1 
ATOM   2322 H  HE1   . HIS A 1 164 ? 33.12923  -27.46458 26.14067 1.000 126.68257 ? 155  HIS A HE1   1 
ATOM   2323 H  HE2   . HIS A 1 164 ? 31.77493  -29.33227 26.66284 1.000 132.78207 ? 155  HIS A HE2   1 
ATOM   2324 N  N     . SER A 1 165 ? 30.05772  -27.03994 19.54198 1.000 96.54662  ? 156  SER A N     1 
ATOM   2325 C  CA    . SER A 1 165 ? 29.92852  -27.27629 18.10765 1.000 96.60607  ? 156  SER A CA    1 
ATOM   2326 C  C     . SER A 1 165 ? 30.90985  -26.42521 17.31310 1.000 95.55591  ? 156  SER A C     1 
ATOM   2327 O  O     . SER A 1 165 ? 31.40119  -26.85902 16.26505 1.000 96.58830  ? 156  SER A O     1 
ATOM   2328 C  CB    . SER A 1 165 ? 28.49768  -26.99337 17.64880 1.000 98.97374  ? 156  SER A CB    1 
ATOM   2329 O  OG    . SER A 1 165 ? 28.36449  -25.66227 17.18185 1.000 94.44763  ? 156  SER A OG    1 
ATOM   2330 H  H     . SER A 1 165 ? 29.35373  -26.72282 19.92071 1.000 115.89916 ? 156  SER A H     1 
ATOM   2331 H  HA    . SER A 1 165 ? 30.12022  -28.21041 17.92998 1.000 115.97049 ? 156  SER A HA    1 
ATOM   2332 H  HB2   . SER A 1 165 ? 28.27173  -27.60326 16.92916 1.000 118.81170 ? 156  SER A HB2   1 
ATOM   2333 H  HB3   . SER A 1 165 ? 27.89527  -27.12586 18.39742 1.000 118.81170 ? 156  SER A HB3   1 
ATOM   2334 H  HG    . SER A 1 165 ? 27.60403  -25.55153 16.84265 1.000 113.38037 ? 156  SER A HG    1 
ATOM   2335 N  N     . GLN A 1 166 ? 31.20216  -25.21743 17.78774 1.000 96.20483  ? 157  GLN A N     1 
ATOM   2336 C  CA    . GLN A 1 166 ? 32.18828  -24.35052 17.16011 1.000 91.82090  ? 157  GLN A CA    1 
ATOM   2337 C  C     . GLN A 1 166 ? 33.58669  -24.54807 17.72812 1.000 93.13562  ? 157  GLN A C     1 
ATOM   2338 O  O     . GLN A 1 166 ? 34.50680  -23.82070 17.34009 1.000 92.11256  ? 157  GLN A O     1 
ATOM   2339 C  CB    . GLN A 1 166 ? 31.77387  -22.88586 17.31810 1.000 87.06637  ? 157  GLN A CB    1 
ATOM   2340 C  CG    . GLN A 1 166 ? 31.84997  -22.08838 16.03262 1.000 88.97696  ? 157  GLN A CG    1 
ATOM   2341 C  CD    . GLN A 1 166 ? 31.22921  -20.71602 16.16810 1.000 87.68175  ? 157  GLN A CD    1 
ATOM   2342 O  OE1   . GLN A 1 166 ? 31.22909  -20.12704 17.24891 1.000 85.80096  ? 157  GLN A OE1   1 
ATOM   2343 N  NE2   . GLN A 1 166 ? 30.68713  -20.20067 15.07047 1.000 89.56140  ? 157  GLN A NE2   1 
ATOM   2344 H  H     . GLN A 1 166 ? 30.83466  -24.87356 18.48508 1.000 115.48901 ? 157  GLN A H     1 
ATOM   2345 H  HA    . GLN A 1 166 ? 32.22024  -24.54952 16.21128 1.000 110.22830 ? 157  GLN A HA    1 
ATOM   2346 H  HB2   . GLN A 1 166 ? 30.85696  -22.85343 17.63293 1.000 104.52286 ? 157  GLN A HB2   1 
ATOM   2347 H  HB3   . GLN A 1 166 ? 32.36154  -22.46344 17.96394 1.000 104.52286 ? 157  GLN A HB3   1 
ATOM   2348 H  HG2   . GLN A 1 166 ? 32.78069  -21.97501 15.78399 1.000 106.81557 ? 157  GLN A HG2   1 
ATOM   2349 H  HG3   . GLN A 1 166 ? 31.37581  -22.56607 15.33414 1.000 106.81557 ? 157  GLN A HG3   1 
ATOM   2350 H  HE21  . GLN A 1 166 ? 30.70185  -20.64495 14.33426 1.000 107.51690 ? 157  GLN A HE21  1 
ATOM   2351 H  HE22  . GLN A 1 166 ? 30.32144  -19.42271 15.09598 1.000 107.51690 ? 157  GLN A HE22  1 
ATOM   2352 N  N     . GLY A 1 167 ? 33.76646  -25.50498 18.63441 1.000 93.04467  ? 158  GLY A N     1 
ATOM   2353 C  CA    . GLY A 1 167 ? 35.07668  -25.76279 19.19671 1.000 95.23814  ? 158  GLY A CA    1 
ATOM   2354 C  C     . GLY A 1 167 ? 35.60849  -24.65504 20.07491 1.000 88.75548  ? 158  GLY A C     1 
ATOM   2355 O  O     . GLY A 1 167 ? 36.82225  -24.43238 20.11023 1.000 91.96503  ? 158  GLY A O     1 
ATOM   2356 H  H     . GLY A 1 167 ? 33.14403  -26.01557 18.93687 1.000 111.69682 ? 158  GLY A H     1 
ATOM   2357 H  HA2   . GLY A 1 167 ? 35.03389  -26.57132 19.73089 1.000 114.32898 ? 158  GLY A HA2   1 
ATOM   2358 H  HA3   . GLY A 1 167 ? 35.70712  -25.89627 18.47171 1.000 114.32898 ? 158  GLY A HA3   1 
ATOM   2359 N  N     . CYS A 1 168 ? 34.73398  -23.94764 20.78423 1.000 83.37121  ? 159  CYS A N     1 
ATOM   2360 C  CA    . CYS A 1 168 ? 35.18930  -22.90338 21.68990 1.000 86.34136  ? 159  CYS A CA    1 
ATOM   2361 C  C     . CYS A 1 168 ? 35.85419  -23.52150 22.91511 1.000 90.87818  ? 159  CYS A C     1 
ATOM   2362 O  O     . CYS A 1 168 ? 35.41305  -24.55357 23.42960 1.000 89.96156  ? 159  CYS A O     1 
ATOM   2363 C  CB    . CYS A 1 168 ? 34.02135  -22.01581 22.11900 1.000 85.01356  ? 159  CYS A CB    1 
ATOM   2364 S  SG    . CYS A 1 168 ? 33.12160  -21.20698 20.76470 1.000 76.70101  ? 159  CYS A SG    1 
ATOM   2365 H  H     . CYS A 1 168 ? 33.88081  -24.05270 20.75849 1.000 100.08867 ? 159  CYS A H     1 
ATOM   2366 H  HA    . CYS A 1 168 ? 35.83754  -22.34318 21.23509 1.000 103.65284 ? 159  CYS A HA    1 
ATOM   2367 H  HB2   . CYS A 1 168 ? 33.38386  -22.56293 22.60394 1.000 102.05949 ? 159  CYS A HB2   1 
ATOM   2368 H  HB3   . CYS A 1 168 ? 34.36516  -21.31637 22.69648 1.000 102.05949 ? 159  CYS A HB3   1 
ATOM   2369 N  N     . GLY A 1 169 ? 36.92453  -22.88459 23.37911 1.000 89.27441  ? 160  GLY A N     1 
ATOM   2370 C  CA    . GLY A 1 169 ? 37.63513  -23.37117 24.54096 1.000 83.63531  ? 160  GLY A CA    1 
ATOM   2371 C  C     . GLY A 1 169 ? 36.80717  -23.26819 25.80683 1.000 86.89965  ? 160  GLY A C     1 
ATOM   2372 O  O     . GLY A 1 169 ? 35.71231  -22.70496 25.83860 1.000 90.34806  ? 160  GLY A O     1 
ATOM   2373 H  H     . GLY A 1 169 ? 37.25502  -22.16899 23.03519 1.000 107.17251 ? 160  GLY A H     1 
ATOM   2374 H  HA2   . GLY A 1 169 ? 37.87300  -24.30178 24.40575 1.000 100.40559 ? 160  GLY A HA2   1 
ATOM   2375 H  HA3   . GLY A 1 169 ? 38.44573  -22.85245 24.66244 1.000 100.40559 ? 160  GLY A HA3   1 
ATOM   2376 N  N     . GLU A 1 170 ? 37.35093  -23.83921 26.87893 1.000 89.61523  ? 161  GLU A N     1 
ATOM   2377 C  CA    . GLU A 1 170 ? 36.68542  -23.77505 28.17247 1.000 91.19412  ? 161  GLU A CA    1 
ATOM   2378 C  C     . GLU A 1 170 ? 36.54175  -22.32315 28.61054 1.000 89.66914  ? 161  GLU A C     1 
ATOM   2379 O  O     . GLU A 1 170 ? 37.50146  -21.54788 28.56100 1.000 88.14743  ? 161  GLU A O     1 
ATOM   2380 C  CB    . GLU A 1 170 ? 37.47263  -24.57128 29.21265 1.000 90.44005  ? 161  GLU A CB    1 
ATOM   2381 H  H     . GLU A 1 170 ? 38.09776  -24.26563 26.88233 1.000 107.58150 ? 161  GLU A H     1 
ATOM   2382 H  HA    . GLU A 1 170 ? 35.80102  -24.16753 28.10394 1.000 109.47617 ? 161  GLU A HA    1 
ATOM   2383 N  N     . GLY A 1 171 ? 35.33504  -21.95563 29.03454 1.000 94.56472  ? 162  GLY A N     1 
ATOM   2384 C  CA    . GLY A 1 171 ? 35.04981  -20.59977 29.44578 1.000 91.40712  ? 162  GLY A CA    1 
ATOM   2385 C  C     . GLY A 1 171 ? 34.66586  -19.65870 28.32614 1.000 88.69350  ? 162  GLY A C     1 
ATOM   2386 O  O     . GLY A 1 171 ? 34.36969  -18.48719 28.59855 1.000 84.21582  ? 162  GLY A O     1 
ATOM   2387 H  H     . GLY A 1 171 ? 34.66056  -22.48617 29.09115 1.000 113.52088 ? 162  GLY A H     1 
ATOM   2388 H  HA2   . GLY A 1 171 ? 34.31735  -20.61641 30.08148 1.000 109.73176 ? 162  GLY A HA2   1 
ATOM   2389 H  HA3   . GLY A 1 171 ? 35.83692  -20.23575 29.88035 1.000 109.73176 ? 162  GLY A HA3   1 
ATOM   2390 N  N     . GLN A 1 172 ? 34.66184  -20.12517 27.08258 1.000 89.40991  ? 163  GLN A N     1 
ATOM   2391 C  CA    . GLN A 1 172 ? 34.28531  -19.31308 25.93688 1.000 82.37250  ? 163  GLN A CA    1 
ATOM   2392 C  C     . GLN A 1 172 ? 32.86403  -19.63724 25.49311 1.000 82.09861  ? 163  GLN A C     1 
ATOM   2393 O  O     . GLN A 1 172 ? 32.30023  -20.68053 25.83289 1.000 85.99208  ? 163  GLN A O     1 
ATOM   2394 C  CB    . GLN A 1 172 ? 35.25268  -19.53434 24.77150 1.000 79.99228  ? 163  GLN A CB    1 
ATOM   2395 C  CG    . GLN A 1 172 ? 36.60592  -18.88145 24.95833 1.000 77.98460  ? 163  GLN A CG    1 
ATOM   2396 C  CD    . GLN A 1 172 ? 37.44908  -18.93458 23.70336 1.000 76.88897  ? 163  GLN A CD    1 
ATOM   2397 O  OE1   . GLN A 1 172 ? 37.27882  -19.81837 22.86240 1.000 87.89266  ? 163  GLN A OE1   1 
ATOM   2398 N  NE2   . GLN A 1 172 ? 38.36078  -17.98137 23.56490 1.000 75.96111  ? 163  GLN A NE2   1 
ATOM   2399 H  H     . GLN A 1 172 ? 34.87947  -20.93057 26.87386 1.000 107.33511 ? 163  GLN A H     1 
ATOM   2400 H  HA    . GLN A 1 172 ? 34.32089  -18.37703 26.18878 1.000 98.89022  ? 163  GLN A HA    1 
ATOM   2401 H  HB2   . GLN A 1 172 ? 35.39762  -20.48753 24.66510 1.000 96.03396  ? 163  GLN A HB2   1 
ATOM   2402 H  HB3   . GLN A 1 172 ? 34.85705  -19.16693 23.96565 1.000 96.03396  ? 163  GLN A HB3   1 
ATOM   2403 H  HG2   . GLN A 1 172 ? 36.47885  -17.94991 25.19706 1.000 93.62474  ? 163  GLN A HG2   1 
ATOM   2404 H  HG3   . GLN A 1 172 ? 37.08613  -19.34224 25.66400 1.000 93.62474  ? 163  GLN A HG3   1 
ATOM   2405 H  HE21  . GLN A 1 172 ? 38.44703  -17.37752 24.17114 1.000 91.19655  ? 163  GLN A HE21  1 
ATOM   2406 H  HE22  . GLN A 1 172 ? 38.86571  -17.96713 22.86888 1.000 91.19655  ? 163  GLN A HE22  1 
ATOM   2407 N  N     . VAL A 1 173 ? 32.28759  -18.71596 24.71998 1.000 76.82049  ? 164  VAL A N     1 
ATOM   2408 C  CA    . VAL A 1 173 ? 30.96158  -18.88889 24.14478 1.000 74.04924  ? 164  VAL A CA    1 
ATOM   2409 C  C     . VAL A 1 173 ? 30.98183  -18.37409 22.71282 1.000 68.54381  ? 164  VAL A C     1 
ATOM   2410 O  O     . VAL A 1 173 ? 31.82795  -17.56366 22.32890 1.000 63.93464  ? 164  VAL A O     1 
ATOM   2411 C  CB    . VAL A 1 173 ? 29.86551  -18.15646 24.95261 1.000 69.55697  ? 164  VAL A CB    1 
ATOM   2412 C  CG1   . VAL A 1 173 ? 29.81288  -18.68158 26.37395 1.000 74.13903  ? 164  VAL A CG1   1 
ATOM   2413 C  CG2   . VAL A 1 173 ? 30.10365  -16.64976 24.94257 1.000 73.19108  ? 164  VAL A CG2   1 
ATOM   2414 H  H     . VAL A 1 173 ? 32.65627  -17.96730 24.51216 1.000 92.22780  ? 164  VAL A H     1 
ATOM   2415 H  HA    . VAL A 1 173 ? 30.74504  -19.83430 24.13053 1.000 88.90230  ? 164  VAL A HA    1 
ATOM   2416 H  HB    . VAL A 1 173 ? 29.00602  -18.32565 24.53602 1.000 83.51158  ? 164  VAL A HB    1 
ATOM   2417 H  HG11  . VAL A 1 173 ? 29.09721  -18.23233 26.85029 1.000 89.01005  ? 164  VAL A HG11  1 
ATOM   2418 H  HG12  . VAL A 1 173 ? 29.64666  -19.63697 26.35169 1.000 89.01005  ? 164  VAL A HG12  1 
ATOM   2419 H  HG13  . VAL A 1 173 ? 30.66187  -18.50356 26.80802 1.000 89.01005  ? 164  VAL A HG13  1 
ATOM   2420 H  HG21  . VAL A 1 173 ? 29.47536  -16.22669 25.54850 1.000 87.87251  ? 164  VAL A HG21  1 
ATOM   2421 H  HG22  . VAL A 1 173 ? 31.01247  -16.47175 25.23111 1.000 87.87251  ? 164  VAL A HG22  1 
ATOM   2422 H  HG23  . VAL A 1 173 ? 29.97101  -16.31508 24.04185 1.000 87.87251  ? 164  VAL A HG23  1 
ATOM   2423 N  N     . ALA A 1 174 ? 30.03642  -18.86701 21.91777 1.000 71.36755  ? 165  ALA A N     1 
ATOM   2424 C  CA    . ALA A 1 174 ? 29.79812  -18.31547 20.58893 1.000 70.12478  ? 165  ALA A CA    1 
ATOM   2425 C  C     . ALA A 1 174 ? 29.23483  -16.90869 20.75065 1.000 67.52369  ? 165  ALA A C     1 
ATOM   2426 O  O     . ALA A 1 174 ? 28.10781  -16.73457 21.22573 1.000 65.87397  ? 165  ALA A O     1 
ATOM   2427 C  CB    . ALA A 1 174 ? 28.84442  -19.21057 19.80509 1.000 72.31501  ? 165  ALA A CB    1 
ATOM   2428 H  H     . ALA A 1 174 ? 29.51901  -19.52178 22.12554 1.000 85.68428  ? 165  ALA A H     1 
ATOM   2429 H  HA    . ALA A 1 174 ? 30.62980  -18.27081 20.09172 1.000 84.19296  ? 165  ALA A HA    1 
ATOM   2430 H  HB1   . ALA A 1 174 ? 28.69405  -18.82147 18.92937 1.000 86.82123  ? 165  ALA A HB1   1 
ATOM   2431 H  HB2   . ALA A 1 174 ? 29.24173  -20.09058 19.71225 1.000 86.82123  ? 165  ALA A HB2   1 
ATOM   2432 H  HB3   . ALA A 1 174 ? 28.00492  -19.27579 20.28665 1.000 86.82123  ? 165  ALA A HB3   1 
ATOM   2433 N  N     . CYS A 1 175 ? 30.01860  -15.90238 20.37549 1.000 68.98447  ? 166  CYS A N     1 
ATOM   2434 C  CA    . CYS A 1 175 ? 29.65855  -14.51235 20.64394 1.000 64.52687  ? 166  CYS A CA    1 
ATOM   2435 C  C     . CYS A 1 175 ? 28.49473  -14.11007 19.74881 1.000 63.23674  ? 166  CYS A C     1 
ATOM   2436 O  O     . CYS A 1 175 ? 28.68002  -13.74956 18.58472 1.000 60.98015  ? 166  CYS A O     1 
ATOM   2437 C  CB    . CYS A 1 175 ? 30.85899  -13.59979 20.43017 1.000 62.54638  ? 166  CYS A CB    1 
ATOM   2438 S  SG    . CYS A 1 175 ? 30.52551  -11.87282 20.84092 1.000 62.66759  ? 166  CYS A SG    1 
ATOM   2439 H  H     . CYS A 1 175 ? 30.76682  -15.99838 19.96251 1.000 82.82458  ? 166  CYS A H     1 
ATOM   2440 H  HA    . CYS A 1 175 ? 29.37353  -14.43286 21.56770 1.000 77.47547  ? 166  CYS A HA    1 
ATOM   2441 H  HB2   . CYS A 1 175 ? 31.58844  -13.90450 20.99227 1.000 75.09887  ? 166  CYS A HB2   1 
ATOM   2442 H  HB3   . CYS A 1 175 ? 31.12049  -13.63920 19.49692 1.000 75.09887  ? 166  CYS A HB3   1 
ATOM   2443 N  N     . LEU A 1 176 ? 27.28589  -14.16378 20.30107 1.000 62.23798  ? 167  LEU A N     1 
ATOM   2444 C  CA    . LEU A 1 176 ? 26.06626  -13.78581 19.60211 1.000 57.99259  ? 167  LEU A CA    1 
ATOM   2445 C  C     . LEU A 1 176 ? 25.27103  -12.84374 20.49203 1.000 55.66513  ? 167  LEU A C     1 
ATOM   2446 O  O     . LEU A 1 176 ? 25.18758  -13.04893 21.70699 1.000 58.31714  ? 167  LEU A O     1 
ATOM   2447 C  CB    . LEU A 1 176 ? 25.23555  -15.02085 19.23863 1.000 57.56533  ? 167  LEU A CB    1 
ATOM   2448 C  CG    . LEU A 1 176 ? 25.90625  -15.95575 18.22728 1.000 59.26743  ? 167  LEU A CG    1 
ATOM   2449 C  CD1   . LEU A 1 176 ? 25.21519  -17.30740 18.17961 1.000 61.87853  ? 167  LEU A CD1   1 
ATOM   2450 C  CD2   . LEU A 1 176 ? 25.91898  -15.31073 16.84782 1.000 56.93751  ? 167  LEU A CD2   1 
ATOM   2451 H  H     . LEU A 1 176 ? 27.14397  -14.42536 21.10793 1.000 74.72879  ? 167  LEU A H     1 
ATOM   2452 H  HA    . LEU A 1 176 ? 26.27470  -13.32066 18.77682 1.000 69.63432  ? 167  LEU A HA    1 
ATOM   2453 H  HB2   . LEU A 1 176 ? 25.07030  -15.53107 20.04688 1.000 69.12161  ? 167  LEU A HB2   1 
ATOM   2454 H  HB3   . LEU A 1 176 ? 24.39496  -14.72598 18.85476 1.000 69.12161  ? 167  LEU A HB3   1 
ATOM   2455 H  HG    . LEU A 1 176 ? 26.82241  -16.11047 18.50587 1.000 71.16413  ? 167  LEU A HG    1 
ATOM   2456 H  HD11  . LEU A 1 176 ? 25.62665  -17.84821 17.48742 1.000 74.29745  ? 167  LEU A HD11  1 
ATOM   2457 H  HD12  . LEU A 1 176 ? 25.31270  -17.74250 19.04105 1.000 74.29745  ? 167  LEU A HD12  1 
ATOM   2458 H  HD13  . LEU A 1 176 ? 24.27515  -17.17462 17.98062 1.000 74.29745  ? 167  LEU A HD13  1 
ATOM   2459 H  HD21  . LEU A 1 176 ? 26.27457  -15.94505 16.20587 1.000 68.36822  ? 167  LEU A HD21  1 
ATOM   2460 H  HD22  . LEU A 1 176 ? 25.01207  -15.06723 16.60467 1.000 68.36822  ? 167  LEU A HD22  1 
ATOM   2461 H  HD23  . LEU A 1 176 ? 26.47823  -14.51864 16.87472 1.000 68.36822  ? 167  LEU A HD23  1 
ATOM   2462 N  N     . PHE A 1 177 ? 24.69208  -11.80708 19.88270 1.000 53.81934  ? 168  PHE A N     1 
ATOM   2463 C  CA    . PHE A 1 177 ? 24.05423  -10.75084 20.66206 1.000 58.27276  ? 168  PHE A CA    1 
ATOM   2464 C  C     . PHE A 1 177 ? 22.96886  -11.31389 21.57283 1.000 58.27693  ? 168  PHE A C     1 
ATOM   2465 O  O     . PHE A 1 177 ? 23.03070  -11.17208 22.79946 1.000 58.00245  ? 168  PHE A O     1 
ATOM   2466 C  CB    . PHE A 1 177 ? 23.46813  -9.68387  19.73464 1.000 55.69018  ? 168  PHE A CB    1 
ATOM   2467 C  CG    . PHE A 1 177 ? 22.91731  -8.49470  20.46662 1.000 53.13958  ? 168  PHE A CG    1 
ATOM   2468 C  CD1   . PHE A 1 177 ? 21.62565  -8.50718  20.96919 1.000 56.18841  ? 168  PHE A CD1   1 
ATOM   2469 C  CD2   . PHE A 1 177 ? 23.69941  -7.37062  20.67020 1.000 56.21752  ? 168  PHE A CD2   1 
ATOM   2470 C  CE1   . PHE A 1 177 ? 21.12080  -7.41611  21.65448 1.000 56.43858  ? 168  PHE A CE1   1 
ATOM   2471 C  CE2   . PHE A 1 177 ? 23.20278  -6.27703  21.35385 1.000 57.11491  ? 168  PHE A CE2   1 
ATOM   2472 C  CZ    . PHE A 1 177 ? 21.90982  -6.29997  21.84723 1.000 57.87255  ? 168  PHE A CZ    1 
ATOM   2473 H  H     . PHE A 1 177 ? 24.65629  -11.69476 19.03082 1.000 64.62643  ? 168  PHE A H     1 
ATOM   2474 H  HA    . PHE A 1 177 ? 24.73195  -10.33249 21.21575 1.000 69.97053  ? 168  PHE A HA    1 
ATOM   2475 H  HB2   . PHE A 1 177 ? 24.16584  -9.36940  19.13865 1.000 66.87143  ? 168  PHE A HB2   1 
ATOM   2476 H  HB3   . PHE A 1 177 ? 22.74574  -10.07788 19.22101 1.000 66.87143  ? 168  PHE A HB3   1 
ATOM   2477 H  HD1   . PHE A 1 177 ? 21.09157  -9.25822  20.84427 1.000 67.46931  ? 168  PHE A HD1   1 
ATOM   2478 H  HD2   . PHE A 1 177 ? 24.56969  -7.35119  20.34289 1.000 67.50423  ? 168  PHE A HD2   1 
ATOM   2479 H  HE1   . PHE A 1 177 ? 20.25155  -7.43478  21.98457 1.000 67.76952  ? 168  PHE A HE1   1 
ATOM   2480 H  HE2   . PHE A 1 177 ? 23.73676  -5.52651  21.48224 1.000 68.58110  ? 168  PHE A HE2   1 
ATOM   2481 H  HZ    . PHE A 1 177 ? 21.57344  -5.56519  22.30749 1.000 69.49027  ? 168  PHE A HZ    1 
ATOM   2482 N  N     . GLU A 1 178 ? 21.95388  -11.94948 20.98482 1.000 55.55572  ? 169  GLU A N     1 
ATOM   2483 C  CA    . GLU A 1 178 ? 20.82488  -12.43436 21.76769 1.000 55.86065  ? 169  GLU A CA    1 
ATOM   2484 C  C     . GLU A 1 178 ? 21.20427  -13.56031 22.71796 1.000 53.99470  ? 169  GLU A C     1 
ATOM   2485 O  O     . GLU A 1 178 ? 20.38844  -13.92476 23.57111 1.000 57.09760  ? 169  GLU A O     1 
ATOM   2486 C  CB    . GLU A 1 178 ? 19.70475  -12.90018 20.83626 1.000 59.07810  ? 169  GLU A CB    1 
ATOM   2487 C  CG    . GLU A 1 178 ? 19.20534  -11.81485 19.89601 1.000 56.81405  ? 169  GLU A CG    1 
ATOM   2488 C  CD    . GLU A 1 178 ? 17.86302  -12.14575 19.27943 1.000 56.87839  ? 169  GLU A CD    1 
ATOM   2489 O  OE1   . GLU A 1 178 ? 17.36994  -13.27332 19.49100 1.000 56.44224  ? 169  GLU A OE1   1 
ATOM   2490 O  OE2   . GLU A 1 178 ? 17.29843  -11.27496 18.58374 1.000 57.38630  ? 169  GLU A OE2   1 
ATOM   2491 H  H     . GLU A 1 178 ? 21.89853  -12.10952 20.14165 1.000 66.71007  ? 169  GLU A H     1 
ATOM   2492 H  HA    . GLU A 1 178 ? 20.48339  -11.70074 22.30256 1.000 67.07600  ? 169  GLU A HA    1 
ATOM   2493 H  HB2   . GLU A 1 178 ? 20.03392  -13.63422 20.29430 1.000 70.93694  ? 169  GLU A HB2   1 
ATOM   2494 H  HB3   . GLU A 1 178 ? 18.95363  -13.19577 21.37418 1.000 70.93694  ? 169  GLU A HB3   1 
ATOM   2495 H  HG2   . GLU A 1 178 ? 19.11168  -10.98614 20.39134 1.000 68.22008  ? 169  GLU A HG2   1 
ATOM   2496 H  HG3   . GLU A 1 178 ? 19.84584  -11.70074 19.17654 1.000 68.22008  ? 169  GLU A HG3   1 
ATOM   2497 N  N     . ASP A 1 179 ? 22.41192  -14.11388 22.60020 1.000 54.11879  ? 170  ASP A N     1 
ATOM   2498 C  CA    . ASP A 1 179 ? 22.82935  -15.17160 23.51125 1.000 58.14909  ? 170  ASP A CA    1 
ATOM   2499 C  C     . ASP A 1 179 ? 23.40471  -14.61990 24.80926 1.000 57.42026  ? 170  ASP A C     1 
ATOM   2500 O  O     . ASP A 1 179 ? 23.26422  -15.25612 25.85974 1.000 58.84550  ? 170  ASP A O     1 
ATOM   2501 C  CB    . ASP A 1 179 ? 23.86078  -16.07618 22.83474 1.000 59.97490  ? 170  ASP A CB    1 
ATOM   2502 C  CG    . ASP A 1 179 ? 23.23378  -17.04382 21.84949 1.000 62.20496  ? 170  ASP A CG    1 
ATOM   2503 O  OD1   . ASP A 1 179 ? 21.98859  -17.11266 21.78489 1.000 60.61440  ? 170  ASP A OD1   1 
ATOM   2504 O  OD2   . ASP A 1 179 ? 23.98966  -17.73791 21.13868 1.000 62.97298  ? 170  ASP A OD2   1 
ATOM   2505 H  H     . ASP A 1 179 ? 22.99778  -13.89656 22.00933 1.000 64.98576  ? 170  ASP A H     1 
ATOM   2506 H  HA    . ASP A 1 179 ? 22.05255  -15.70959 23.73044 1.000 69.82212  ? 170  ASP A HA    1 
ATOM   2507 H  HB2   . ASP A 1 179 ? 24.49611  -15.52518 22.35137 1.000 72.01309  ? 170  ASP A HB2   1 
ATOM   2508 H  HB3   . ASP A 1 179 ? 24.32041  -16.59468 23.51356 1.000 72.01309  ? 170  ASP A HB3   1 
ATOM   2509 N  N     . VAL A 1 180 ? 24.04591  -13.45224 24.76487 1.000 56.30477  ? 171  VAL A N     1 
ATOM   2510 C  CA    . VAL A 1 180 ? 24.68396  -12.88777 25.94160 1.000 60.55015  ? 171  VAL A CA    1 
ATOM   2511 C  C     . VAL A 1 180 ? 23.90587  -11.71273 26.52487 1.000 58.16213  ? 171  VAL A C     1 
ATOM   2512 O  O     . VAL A 1 180 ? 23.90836  -11.53596 27.74851 1.000 58.09348  ? 171  VAL A O     1 
ATOM   2513 C  CB    . VAL A 1 180 ? 26.13998  -12.47351 25.63090 1.000 61.05110  ? 171  VAL A CB    1 
ATOM   2514 C  CG1   . VAL A 1 180 ? 26.93558  -13.66883 25.12190 1.000 53.03627  ? 171  VAL A CG1   1 
ATOM   2515 C  CG2   . VAL A 1 180 ? 26.17867  -11.32619 24.62705 1.000 58.96816  ? 171  VAL A CG2   1 
ATOM   2516 H  H     . VAL A 1 180 ? 24.12322  -12.96828 24.05819 1.000 67.60894  ? 171  VAL A H     1 
ATOM   2517 H  HA    . VAL A 1 180 ? 24.70740  -13.56655 26.63414 1.000 72.70339  ? 171  VAL A HA    1 
ATOM   2518 H  HB    . VAL A 1 180 ? 26.55554  -12.16038 26.44953 1.000 73.30454  ? 171  VAL A HB    1 
ATOM   2519 H  HG11  . VAL A 1 180 ? 27.85670  -13.39876 24.98225 1.000 63.68674  ? 171  VAL A HG11  1 
ATOM   2520 H  HG12  . VAL A 1 180 ? 26.89545  -14.37891 25.78151 1.000 63.68674  ? 171  VAL A HG12  1 
ATOM   2521 H  HG13  . VAL A 1 180 ? 26.54938  -13.97218 24.28541 1.000 63.68674  ? 171  VAL A HG13  1 
ATOM   2522 H  HG21  . VAL A 1 180 ? 27.10084  -11.15236 24.38153 1.000 70.80500  ? 171  VAL A HG21  1 
ATOM   2523 H  HG22  . VAL A 1 180 ? 25.66873  -11.57703 23.84096 1.000 70.80500  ? 171  VAL A HG22  1 
ATOM   2524 H  HG23  . VAL A 1 180 ? 25.79048  -10.53640 25.03502 1.000 70.80500  ? 171  VAL A HG23  1 
ATOM   2525 N  N     . VAL A 1 181 ? 23.24130  -10.91307 25.69930 1.000 61.94030  ? 172  VAL A N     1 
ATOM   2526 C  CA    . VAL A 1 181 ? 22.49329  -9.74910  26.16925 1.000 59.01398  ? 172  VAL A CA    1 
ATOM   2527 C  C     . VAL A 1 181 ? 21.07458  -10.20357 26.49759 1.000 57.48444  ? 172  VAL A C     1 
ATOM   2528 O  O     . VAL A 1 181 ? 20.37870  -10.71061 25.60453 1.000 58.72138  ? 172  VAL A O     1 
ATOM   2529 C  CB    . VAL A 1 181 ? 22.48167  -8.62867  25.12216 1.000 58.39431  ? 172  VAL A CB    1 
ATOM   2530 C  CG1   . VAL A 1 181 ? 21.74714  -7.40685  25.66107 1.000 56.04056  ? 172  VAL A CG1   1 
ATOM   2531 C  CG2   . VAL A 1 181 ? 23.90379  -8.26354  24.71926 1.000 61.76433  ? 172  VAL A CG2   1 
ATOM   2532 H  H     . VAL A 1 181 ? 23.20696  -11.02441 24.84723 1.000 74.37157  ? 172  VAL A H     1 
ATOM   2533 H  HA    . VAL A 1 181 ? 22.90375  -9.40701  26.97881 1.000 70.85999  ? 172  VAL A HA    1 
ATOM   2534 H  HB    . VAL A 1 181 ? 22.01363  -8.94013  24.33170 1.000 70.11639  ? 172  VAL A HB    1 
ATOM   2535 H  HG11  . VAL A 1 181 ? 21.85407  -6.67291  25.03593 1.000 67.29189  ? 172  VAL A HG11  1 
ATOM   2536 H  HG12  . VAL A 1 181 ? 20.80661  -7.62225  25.76057 1.000 67.29189  ? 172  VAL A HG12  1 
ATOM   2537 H  HG13  . VAL A 1 181 ? 22.12415  -7.16589  26.52171 1.000 67.29189  ? 172  VAL A HG13  1 
ATOM   2538 H  HG21  . VAL A 1 181 ? 23.87917  -7.47770  24.15115 1.000 74.16041  ? 172  VAL A HG21  1 
ATOM   2539 H  HG22  . VAL A 1 181 ? 24.42067  -8.07766  25.51875 1.000 74.16041  ? 172  VAL A HG22  1 
ATOM   2540 H  HG23  . VAL A 1 181 ? 24.29646  -9.00805  24.23716 1.000 74.16041  ? 172  VAL A HG23  1 
ATOM   2541 N  N     . PRO A 1 182 ? 20.61278  -10.05346 27.74047 1.000 55.09568  ? 173  PRO A N     1 
ATOM   2542 C  CA    . PRO A 1 182 ? 19.23821  -10.45595 28.06073 1.000 53.17666  ? 173  PRO A CA    1 
ATOM   2543 C  C     . PRO A 1 182 ? 18.23373  -9.59526  27.31422 1.000 48.13061  ? 173  PRO A C     1 
ATOM   2544 O  O     . PRO A 1 182 ? 18.44469  -8.39792  27.11050 1.000 56.13964  ? 173  PRO A O     1 
ATOM   2545 C  CB    . PRO A 1 182 ? 19.14142  -10.24080 29.57772 1.000 52.47516  ? 173  PRO A CB    1 
ATOM   2546 C  CG    . PRO A 1 182 ? 20.55406  -10.14160 30.05862 1.000 53.06914  ? 173  PRO A CG    1 
ATOM   2547 C  CD    . PRO A 1 182 ? 21.32466  -9.54466  28.92556 1.000 54.04082  ? 173  PRO A CD    1 
ATOM   2548 H  HA    . PRO A 1 182 ? 19.09261  -11.39286 27.85602 1.000 63.85521  ? 173  PRO A HA    1 
ATOM   2549 H  HB2   . PRO A 1 182 ? 18.65548  -9.42190  29.76256 1.000 63.01341  ? 173  PRO A HB2   1 
ATOM   2550 H  HB3   . PRO A 1 182 ? 18.68924  -10.99465 29.98778 1.000 63.01341  ? 173  PRO A HB3   1 
ATOM   2551 H  HG2   . PRO A 1 182 ? 20.59469  -9.57025  30.84143 1.000 63.72619  ? 173  PRO A HG2   1 
ATOM   2552 H  HG3   . PRO A 1 182 ? 20.88961  -11.02555 30.27529 1.000 63.72619  ? 173  PRO A HG3   1 
ATOM   2553 H  HD2   . PRO A 1 182 ? 21.29509  -8.57567  28.95844 1.000 64.89221  ? 173  PRO A HD2   1 
ATOM   2554 H  HD3   . PRO A 1 182 ? 22.24566  -9.84894  28.93410 1.000 64.89221  ? 173  PRO A HD3   1 
ATOM   2555 N  N     . MET A 1 183 ? 17.12602  -10.21441 26.90956 1.000 48.23643  ? 174  MET A N     1 
ATOM   2556 C  CA    . MET A 1 183 ? 16.12557  -9.47830  26.14708 1.000 47.59734  ? 174  MET A CA    1 
ATOM   2557 C  C     . MET A 1 183 ? 15.24468  -8.62203  27.04824 1.000 53.02964  ? 174  MET A C     1 
ATOM   2558 O  O     . MET A 1 183 ? 14.73180  -7.58989  26.60053 1.000 52.76193  ? 174  MET A O     1 
ATOM   2559 C  CB    . MET A 1 183 ? 15.27035  -10.44595 25.32948 1.000 48.94436  ? 174  MET A CB    1 
ATOM   2560 C  CG    . MET A 1 183 ? 14.73369  -9.85941  24.02834 1.000 50.78883  ? 174  MET A CG    1 
ATOM   2561 S  SD    . MET A 1 183 ? 16.00237  -9.28850  22.87023 1.000 67.95537  ? 174  MET A SD    1 
ATOM   2562 C  CE    . MET A 1 183 ? 16.94029  -10.79159 22.59013 1.000 64.42936  ? 174  MET A CE    1 
ATOM   2563 H  H     . MET A 1 183 ? 16.93583  -11.03944 27.06037 1.000 57.92694  ? 174  MET A H     1 
ATOM   2564 H  HA    . MET A 1 183 ? 16.58087  -8.89549  25.51944 1.000 57.16002  ? 174  MET A HA    1 
ATOM   2565 H  HB2   . MET A 1 183 ? 15.80878  -11.22040 25.10314 1.000 58.77645  ? 174  MET A HB2   1 
ATOM   2566 H  HB3   . MET A 1 183 ? 14.50911  -10.71656 25.86631 1.000 58.77645  ? 174  MET A HB3   1 
ATOM   2567 H  HG2   . MET A 1 183 ? 14.21189  -10.54043 23.57574 1.000 60.98981  ? 174  MET A HG2   1 
ATOM   2568 H  HG3   . MET A 1 183 ? 14.17156  -9.09844  24.24241 1.000 60.98981  ? 174  MET A HG3   1 
ATOM   2569 H  HE1   . MET A 1 183 ? 17.74113  -10.57506 22.08747 1.000 77.35845  ? 174  MET A HE1   1 
ATOM   2570 H  HE2   . MET A 1 183 ? 17.18162  -11.17749 23.44672 1.000 77.35845  ? 174  MET A HE2   1 
ATOM   2571 H  HE3   . MET A 1 183 ? 16.39349  -11.41612 22.08825 1.000 77.35845  ? 174  MET A HE3   1 
ATOM   2572 N  N     . ASN A 1 184 ? 15.05880  -9.01966  28.31138 1.000 51.78794  ? 175  ASN A N     1 
ATOM   2573 C  CA    . ASN A 1 184 ? 14.31045  -8.17089  29.23311 1.000 53.76119  ? 175  ASN A CA    1 
ATOM   2574 C  C     . ASN A 1 184 ? 15.04182  -6.85974  29.49289 1.000 51.21109  ? 175  ASN A C     1 
ATOM   2575 O  O     . ASN A 1 184 ? 14.40030  -5.83097  29.73206 1.000 54.67205  ? 175  ASN A O     1 
ATOM   2576 C  CB    . ASN A 1 184 ? 14.04074  -8.90595  30.54896 1.000 51.53788  ? 175  ASN A CB    1 
ATOM   2577 C  CG    . ASN A 1 184 ? 15.27876  -9.58259  31.11951 1.000 54.48599  ? 175  ASN A CG    1 
ATOM   2578 O  OD1   . ASN A 1 184 ? 16.40979  -9.26858  30.74522 1.000 57.81611  ? 175  ASN A OD1   1 
ATOM   2579 N  ND2   . ASN A 1 184 ? 15.06417  -10.51961 32.03657 1.000 50.64747  ? 175  ASN A ND2   1 
ATOM   2580 H  H     . ASN A 1 184 ? 15.34862  -9.75623  28.64764 1.000 62.18874  ? 175  ASN A H     1 
ATOM   2581 H  HA    . ASN A 1 184 ? 13.44911  -7.96627  28.83673 1.000 64.55664  ? 175  ASN A HA    1 
ATOM   2582 H  HB2   . ASN A 1 184 ? 13.71969  -8.26831  31.20564 1.000 61.88868  ? 175  ASN A HB2   1 
ATOM   2583 H  HB3   . ASN A 1 184 ? 13.37051  -9.59019  30.39564 1.000 61.88868  ? 175  ASN A HB3   1 
ATOM   2584 H  HD21  . ASN A 1 184 ? 14.26057  -10.71203 32.27487 1.000 60.82018  ? 175  ASN A HD21  1 
ATOM   2585 H  HD22  . ASN A 1 184 ? 15.72888  -10.93375 32.39190 1.000 60.82018  ? 175  ASN A HD22  1 
ATOM   2586 N  N     . TYR A 1 185 ? 16.37438  -6.87197  29.44434 1.000 50.46765  ? 176  TYR A N     1 
ATOM   2587 C  CA    . TYR A 1 185 ? 17.12243  -5.62235  29.51882 1.000 52.41283  ? 176  TYR A CA    1 
ATOM   2588 C  C     . TYR A 1 185 ? 16.86348  -4.76259  28.28805 1.000 49.53693  ? 176  TYR A C     1 
ATOM   2589 O  O     . TYR A 1 185 ? 16.59287  -3.56143  28.39991 1.000 47.18390  ? 176  TYR A O     1 
ATOM   2590 C  CB    . TYR A 1 185 ? 18.61745  -5.90953  29.66259 1.000 49.11941  ? 176  TYR A CB    1 
ATOM   2591 C  CG    . TYR A 1 185 ? 19.49055  -4.70682  29.37848 1.000 48.73839  ? 176  TYR A CG    1 
ATOM   2592 C  CD1   . TYR A 1 185 ? 19.79899  -3.79533  30.37994 1.000 48.45297  ? 176  TYR A CD1   1 
ATOM   2593 C  CD2   . TYR A 1 185 ? 20.00216  -4.47942  28.10587 1.000 46.35436  ? 176  TYR A CD2   1 
ATOM   2594 C  CE1   . TYR A 1 185 ? 20.59370  -2.69431  30.12247 1.000 46.32062  ? 176  TYR A CE1   1 
ATOM   2595 C  CE2   . TYR A 1 185 ? 20.79402  -3.38119  27.83986 1.000 39.96929  ? 176  TYR A CE2   1 
ATOM   2596 C  CZ    . TYR A 1 185 ? 21.08686  -2.49294  28.85049 1.000 44.55701  ? 176  TYR A CZ    1 
ATOM   2597 O  OH    . TYR A 1 185 ? 21.87757  -1.39939  28.58732 1.000 53.37001  ? 176  TYR A OH    1 
ATOM   2598 H  H     . TYR A 1 185 ? 16.85916  -7.57840  29.36985 1.000 60.60439  ? 176  TYR A H     1 
ATOM   2599 H  HA    . TYR A 1 185 ? 16.83363  -5.13172  30.30418 1.000 62.93862  ? 176  TYR A HA    1 
ATOM   2600 H  HB2   . TYR A 1 185 ? 18.79497  -6.19808  30.57150 1.000 58.98650  ? 176  TYR A HB2   1 
ATOM   2601 H  HB3   . TYR A 1 185 ? 18.86332  -6.60991  29.03816 1.000 58.98650  ? 176  TYR A HB3   1 
ATOM   2602 H  HD1   . TYR A 1 185 ? 19.46530  -3.92801  31.23781 1.000 58.18678  ? 176  TYR A HD1   1 
ATOM   2603 H  HD2   . TYR A 1 185 ? 19.80716  -5.07829  27.42159 1.000 55.66845  ? 176  TYR A HD2   1 
ATOM   2604 H  HE1   . TYR A 1 185 ? 20.79465  -2.09295  30.80283 1.000 55.62796  ? 176  TYR A HE1   1 
ATOM   2605 H  HE2   . TYR A 1 185 ? 21.12796  -3.24174  26.98315 1.000 48.00637  ? 176  TYR A HE2   1 
ATOM   2606 H  HH    . TYR A 1 185 ? 21.96073  -0.93160  29.28004 1.000 64.08723  ? 176  TYR A HH    1 
ATOM   2607 N  N     . MET A 1 186 ? 16.94178  -5.36639  27.10025 1.000 50.11630  ? 177  MET A N     1 
ATOM   2608 C  CA    . MET A 1 186 ? 16.77760  -4.60408  25.86660 1.000 54.35692  ? 177  MET A CA    1 
ATOM   2609 C  C     . MET A 1 186 ? 15.38104  -4.00273  25.75454 1.000 47.47120  ? 177  MET A C     1 
ATOM   2610 O  O     . MET A 1 186 ? 15.21625  -2.90107  25.22064 1.000 51.18028  ? 177  MET A O     1 
ATOM   2611 C  CB    . MET A 1 186 ? 17.06735  -5.49530  24.65803 1.000 52.48929  ? 177  MET A CB    1 
ATOM   2612 C  CG    . MET A 1 186 ? 18.54100  -5.81809  24.44880 1.000 54.05564  ? 177  MET A CG    1 
ATOM   2613 S  SD    . MET A 1 186 ? 19.59525  -4.34996  24.35432 1.000 51.20337  ? 177  MET A SD    1 
ATOM   2614 C  CE    . MET A 1 186 ? 18.71196  -3.34657  23.15906 1.000 51.23221  ? 177  MET A CE    1 
ATOM   2615 H  H     . MET A 1 186 ? 17.08735  -6.20598  26.98405 1.000 60.18278  ? 177  MET A H     1 
ATOM   2616 H  HA    . MET A 1 186 ? 17.42436  -3.88120  25.87277 1.000 65.27152  ? 177  MET A HA    1 
ATOM   2617 H  HB2   . MET A 1 186 ? 16.59719  -6.33572  24.77437 1.000 63.03037  ? 177  MET A HB2   1 
ATOM   2618 H  HB3   . MET A 1 186 ? 16.74994  -5.04537  23.85946 1.000 63.03037  ? 177  MET A HB3   1 
ATOM   2619 H  HG2   . MET A 1 186 ? 18.85160  -6.35920  25.19151 1.000 64.90998  ? 177  MET A HG2   1 
ATOM   2620 H  HG3   . MET A 1 186 ? 18.63931  -6.30805  23.61743 1.000 64.90998  ? 177  MET A HG3   1 
ATOM   2621 H  HE1   . MET A 1 186 ? 19.21793  -2.53608  22.99174 1.000 61.52187  ? 177  MET A HE1   1 
ATOM   2622 H  HE2   . MET A 1 186 ? 18.61241  -3.85020  22.33605 1.000 61.52187  ? 177  MET A HE2   1 
ATOM   2623 H  HE3   . MET A 1 186 ? 17.83887  -3.12331  23.51790 1.000 61.52187  ? 177  MET A HE3   1 
ATOM   2624 N  N     . VAL A 1 187 ? 14.36272  -4.71122  26.24285 1.000 48.01817  ? 178  VAL A N     1 
ATOM   2625 C  CA    . VAL A 1 187 ? 12.97858  -4.27506  26.08965 1.000 50.61343  ? 178  VAL A CA    1 
ATOM   2626 C  C     . VAL A 1 187 ? 12.59048  -3.34430  27.23213 1.000 55.78277  ? 178  VAL A C     1 
ATOM   2627 O  O     . VAL A 1 187 ? 12.22428  -2.18572  27.00377 1.000 49.05327  ? 178  VAL A O     1 
ATOM   2628 C  CB    . VAL A 1 187 ? 12.02955  -5.48674  26.02119 1.000 55.27464  ? 178  VAL A CB    1 
ATOM   2629 C  CG1   . VAL A 1 187 ? 10.58111  -5.02726  25.97509 1.000 57.66826  ? 178  VAL A CG1   1 
ATOM   2630 C  CG2   . VAL A 1 187 ? 12.35971  -6.35757  24.81287 1.000 51.04022  ? 178  VAL A CG2   1 
ATOM   2631 H  H     . VAL A 1 187 ? 14.44998  -5.45284  26.66946 1.000 57.66502  ? 178  VAL A H     1 
ATOM   2632 H  HA    . VAL A 1 187 ? 12.90370  -3.77037  25.26468 1.000 60.77933  ? 178  VAL A HA    1 
ATOM   2633 H  HB    . VAL A 1 187 ? 12.14881  -6.02416  26.81984 1.000 66.37279  ? 178  VAL A HB    1 
ATOM   2634 H  HG11  . VAL A 1 187 ? 10.02090  -5.77461  25.71332 1.000 69.24512  ? 178  VAL A HG11  1 
ATOM   2635 H  HG12  . VAL A 1 187 ? 10.32175  -4.71169  26.85489 1.000 69.24512  ? 178  VAL A HG12  1 
ATOM   2636 H  HG13  . VAL A 1 187 ? 10.49803  -4.30913  25.32834 1.000 69.24512  ? 178  VAL A HG13  1 
ATOM   2637 H  HG21  . VAL A 1 187 ? 11.73900  -7.10230  24.78127 1.000 61.29147  ? 178  VAL A HG21  1 
ATOM   2638 H  HG22  . VAL A 1 187 ? 12.27738  -5.82393  24.00705 1.000 61.29147  ? 178  VAL A HG22  1 
ATOM   2639 H  HG23  . VAL A 1 187 ? 13.26779  -6.68730  24.89991 1.000 61.29147  ? 178  VAL A HG23  1 
ATOM   2640 N  N     . TYR A 1 188 ? 12.66607  -3.84284  28.46920 1.000 50.34976  ? 179  TYR A N     1 
ATOM   2641 C  CA    . TYR A 1 188 ? 12.22169  -3.05210  29.61295 1.000 53.63715  ? 179  TYR A CA    1 
ATOM   2642 C  C     . TYR A 1 188 ? 13.19952  -1.92471  29.92189 1.000 53.26892  ? 179  TYR A C     1 
ATOM   2643 O  O     . TYR A 1 188 ? 12.80618  -0.75673  30.02356 1.000 48.42612  ? 179  TYR A O     1 
ATOM   2644 C  CB    . TYR A 1 188 ? 12.04822  -3.94684  30.84275 1.000 55.10203  ? 179  TYR A CB    1 
ATOM   2645 C  CG    . TYR A 1 188 ? 10.90845  -4.93726  30.74501 1.000 58.55556  ? 179  TYR A CG    1 
ATOM   2646 C  CD1   . TYR A 1 188 ? 9.70231   -4.58835  30.14980 1.000 61.70704  ? 179  TYR A CD1   1 
ATOM   2647 C  CD2   . TYR A 1 188 ? 11.04046  -6.22420  31.24806 1.000 60.29466  ? 179  TYR A CD2   1 
ATOM   2648 C  CE1   . TYR A 1 188 ? 8.66199   -5.49215  30.05989 1.000 63.05081  ? 179  TYR A CE1   1 
ATOM   2649 C  CE2   . TYR A 1 188 ? 10.00583  -7.13451  31.16239 1.000 60.79472  ? 179  TYR A CE2   1 
ATOM   2650 C  CZ    . TYR A 1 188 ? 8.81888   -6.76308  30.56747 1.000 59.83589  ? 179  TYR A CZ    1 
ATOM   2651 O  OH    . TYR A 1 188 ? 7.78434   -7.66520  30.47749 1.000 59.88596  ? 179  TYR A OH    1 
ATOM   2652 H  H     . TYR A 1 188 ? 12.96620  -4.62386  28.66802 1.000 60.46292  ? 179  TYR A H     1 
ATOM   2653 H  HA    . TYR A 1 188 ? 11.36130  -2.66093  29.39474 1.000 64.40779  ? 179  TYR A HA    1 
ATOM   2654 H  HB2   . TYR A 1 188 ? 12.86521  -4.45304  30.97386 1.000 66.16565  ? 179  TYR A HB2   1 
ATOM   2655 H  HB3   . TYR A 1 188 ? 11.88019  -3.38263  31.61368 1.000 66.16565  ? 179  TYR A HB3   1 
ATOM   2656 H  HD1   . TYR A 1 188 ? 9.59371   -3.73111  29.80593 1.000 74.09166  ? 179  TYR A HD1   1 
ATOM   2657 H  HD2   . TYR A 1 188 ? 11.83990  -6.47780  31.64991 1.000 72.39681  ? 179  TYR A HD2   1 
ATOM   2658 H  HE1   . TYR A 1 188 ? 7.86027   -5.24421  29.65904 1.000 75.70419  ? 179  TYR A HE1   1 
ATOM   2659 H  HE2   . TYR A 1 188 ? 10.10903  -7.99330  31.50404 1.000 72.99688  ? 179  TYR A HE2   1 
ATOM   2660 H  HH    . TYR A 1 188 ? 7.98973   -8.37810  30.87144 1.000 71.90636  ? 179  TYR A HH    1 
ATOM   2661 N  N     . PHE A 1 189 ? 14.47961  -2.25658  30.08338 1.000 49.85969  ? 180  PHE A N     1 
ATOM   2662 C  CA    . PHE A 1 189 ? 15.44873  -1.26929  30.54615 1.000 49.69979  ? 180  PHE A CA    1 
ATOM   2663 C  C     . PHE A 1 189 ? 15.88837  -0.34699  29.41414 1.000 48.66862  ? 180  PHE A C     1 
ATOM   2664 O  O     . PHE A 1 189 ? 15.76556  0.87863   29.51393 1.000 48.41777  ? 180  PHE A O     1 
ATOM   2665 C  CB    . PHE A 1 189 ? 16.65581  -1.98044  31.16439 1.000 52.10215  ? 180  PHE A CB    1 
ATOM   2666 C  CG    . PHE A 1 189 ? 17.56765  -1.07262  31.93780 1.000 49.45641  ? 180  PHE A CG    1 
ATOM   2667 C  CD1   . PHE A 1 189 ? 18.58400  -0.38109  31.29976 1.000 50.42980  ? 180  PHE A CD1   1 
ATOM   2668 C  CD2   . PHE A 1 189 ? 17.41554  -0.92086  33.30596 1.000 48.24545  ? 180  PHE A CD2   1 
ATOM   2669 C  CE1   . PHE A 1 189 ? 19.42848  0.44763   32.00983 1.000 50.99790  ? 180  PHE A CE1   1 
ATOM   2670 C  CE2   . PHE A 1 189 ? 18.25693  -0.09444  34.02199 1.000 46.05333  ? 180  PHE A CE2   1 
ATOM   2671 C  CZ    . PHE A 1 189 ? 19.26463  0.59230   33.37248 1.000 55.19701  ? 180  PHE A CZ    1 
ATOM   2672 H  H     . PHE A 1 189 ? 14.80747  -3.03736  29.93345 1.000 59.87485  ? 180  PHE A H     1 
ATOM   2673 H  HA    . PHE A 1 189 ? 15.03485  -0.72057  31.23062 1.000 59.68296  ? 180  PHE A HA    1 
ATOM   2674 H  HB2   . PHE A 1 189 ? 16.33573  -2.66513  31.77238 1.000 62.56580  ? 180  PHE A HB2   1 
ATOM   2675 H  HB3   . PHE A 1 189 ? 17.17628  -2.38540  30.45304 1.000 62.56580  ? 180  PHE A HB3   1 
ATOM   2676 H  HD1   . PHE A 1 189 ? 18.69867  -0.47640  30.38179 1.000 60.55897  ? 180  PHE A HD1   1 
ATOM   2677 H  HD2   . PHE A 1 189 ? 16.73854  -1.38126  33.74709 1.000 57.93775  ? 180  PHE A HD2   1 
ATOM   2678 H  HE1   . PHE A 1 189 ? 20.10695  0.90793   31.57084 1.000 61.24070  ? 180  PHE A HE1   1 
ATOM   2679 H  HE2   . PHE A 1 189 ? 18.14594  0.00022   34.94048 1.000 55.30722  ? 180  PHE A HE2   1 
ATOM   2680 H  HZ    . PHE A 1 189 ? 19.83175  1.15128   33.85291 1.000 66.27963  ? 180  PHE A HZ    1 
ATOM   2681 N  N     . ASN A 1 190 ? 16.40176  -0.91900  28.32467 1.000 51.28968  ? 181  ASN A N     1 
ATOM   2682 C  CA    . ASN A 1 190 ? 16.97523  -0.09634  27.26514 1.000 51.16460  ? 181  ASN A CA    1 
ATOM   2683 C  C     . ASN A 1 190 ? 15.88790  0.60701   26.45934 1.000 57.71706  ? 181  ASN A C     1 
ATOM   2684 O  O     . ASN A 1 190 ? 15.88544  1.83746   26.33831 1.000 51.06030  ? 181  ASN A O     1 
ATOM   2685 C  CB    . ASN A 1 190 ? 17.85447  -0.95225  26.35080 1.000 50.85810  ? 181  ASN A CB    1 
ATOM   2686 C  CG    . ASN A 1 190 ? 18.65870  -0.11654  25.36799 1.000 55.47782  ? 181  ASN A CG    1 
ATOM   2687 O  OD1   . ASN A 1 190 ? 18.25525  0.07674   24.21989 1.000 57.39347  ? 181  ASN A OD1   1 
ATOM   2688 N  ND2   . ASN A 1 190 ? 19.79980  0.39051   25.81978 1.000 50.96535  ? 181  ASN A ND2   1 
ATOM   2689 H  H     . ASN A 1 190 ? 16.42919  -1.76605  28.17851 1.000 61.59084  ? 181  ASN A H     1 
ATOM   2690 H  HA    . ASN A 1 190 ? 17.53432  0.58344   27.67284 1.000 61.44073  ? 181  ASN A HA    1 
ATOM   2691 H  HB2   . ASN A 1 190 ? 18.47720  -1.45997  26.89424 1.000 61.07294  ? 181  ASN A HB2   1 
ATOM   2692 H  HB3   . ASN A 1 190 ? 17.29018  -1.55520  25.84194 1.000 61.07294  ? 181  ASN A HB3   1 
ATOM   2693 H  HD21  . ASN A 1 190 ? 20.29154  0.87064   25.30280 1.000 61.20164  ? 181  ASN A HD21  1 
ATOM   2694 H  HD22  . ASN A 1 190 ? 20.04709  0.23877   26.62937 1.000 61.20164  ? 181  ASN A HD22  1 
ATOM   2695 N  N     . PHE A 1 191 ? 14.95088  -0.15815  25.89770 1.000 47.84417  ? 182  PHE A N     1 
ATOM   2696 C  CA    . PHE A 1 191 ? 13.98531  0.42520   24.97068 1.000 51.54883  ? 182  PHE A CA    1 
ATOM   2697 C  C     . PHE A 1 191 ? 12.94499  1.26706   25.70501 1.000 51.43716  ? 182  PHE A C     1 
ATOM   2698 O  O     . PHE A 1 191 ? 12.85162  2.48166   25.49452 1.000 51.37637  ? 182  PHE A O     1 
ATOM   2699 C  CB    . PHE A 1 191 ? 13.31279  -0.67785  24.15017 1.000 51.29338  ? 182  PHE A CB    1 
ATOM   2700 C  CG    . PHE A 1 191 ? 12.25146  -0.17220  23.21583 1.000 55.45614  ? 182  PHE A CG    1 
ATOM   2701 C  CD1   . PHE A 1 191 ? 12.49307  0.92329   22.40120 1.000 56.29667  ? 182  PHE A CD1   1 
ATOM   2702 C  CD2   . PHE A 1 191 ? 11.01430  -0.79173  23.14738 1.000 54.24121  ? 182  PHE A CD2   1 
ATOM   2703 C  CE1   . PHE A 1 191 ? 11.51915  1.39253   21.53890 1.000 57.18508  ? 182  PHE A CE1   1 
ATOM   2704 C  CE2   . PHE A 1 191 ? 10.03737  -0.32706  22.28661 1.000 54.60105  ? 182  PHE A CE2   1 
ATOM   2705 C  CZ    . PHE A 1 191 ? 10.28989  0.76577   21.48233 1.000 57.99469  ? 182  PHE A CZ    1 
ATOM   2706 H  H     . PHE A 1 191 ? 14.85527  -1.00177  26.03473 1.000 57.45622  ? 182  PHE A H     1 
ATOM   2707 H  HA    . PHE A 1 191 ? 14.45999  1.00924   24.35873 1.000 61.90181  ? 182  PHE A HA    1 
ATOM   2708 H  HB2   . PHE A 1 191 ? 13.98791  -1.12613  23.61711 1.000 61.59527  ? 182  PHE A HB2   1 
ATOM   2709 H  HB3   . PHE A 1 191 ? 12.89658  -1.30919  24.75768 1.000 61.59527  ? 182  PHE A HB3   1 
ATOM   2710 H  HD1   . PHE A 1 191 ? 13.31994  1.34760   22.43506 1.000 67.59922  ? 182  PHE A HD1   1 
ATOM   2711 H  HD2   . PHE A 1 191 ? 10.83890  -1.52877  23.68673 1.000 65.13267  ? 182  PHE A HD2   1 
ATOM   2712 H  HE1   . PHE A 1 191 ? 11.69172  2.12905   20.99792 1.000 68.66532  ? 182  PHE A HE1   1 
ATOM   2713 H  HE2   . PHE A 1 191 ? 9.21030   -0.75071  22.24951 1.000 65.56448  ? 182  PHE A HE2   1 
ATOM   2714 H  HZ    . PHE A 1 191 ? 9.63330   1.07954   20.90324 1.000 69.63685  ? 182  PHE A HZ    1 
ATOM   2715 N  N     . PHE A 1 192 ? 12.14760  0.63859   26.57018 1.000 48.43171  ? 183  PHE A N     1 
ATOM   2716 C  CA    . PHE A 1 192 ? 11.07044  1.35867   27.24254 1.000 53.45802  ? 183  PHE A CA    1 
ATOM   2717 C  C     . PHE A 1 192 ? 11.61323  2.51404   28.07952 1.000 50.69224  ? 183  PHE A C     1 
ATOM   2718 O  O     . PHE A 1 192 ? 11.22276  3.67274   27.89489 1.000 51.19452  ? 183  PHE A O     1 
ATOM   2719 C  CB    . PHE A 1 192 ? 10.26101  0.40279   28.12449 1.000 53.00446  ? 183  PHE A CB    1 
ATOM   2720 C  CG    . PHE A 1 192 ? 9.36734   -0.54245  27.35880 1.000 57.61471  ? 183  PHE A CG    1 
ATOM   2721 C  CD1   . PHE A 1 192 ? 9.29457   -0.50607  25.97430 1.000 57.96411  ? 183  PHE A CD1   1 
ATOM   2722 C  CD2   . PHE A 1 192 ? 8.59018   -1.46849  28.03674 1.000 62.06843  ? 183  PHE A CD2   1 
ATOM   2723 C  CE1   . PHE A 1 192 ? 8.46890   -1.37878  25.28402 1.000 60.06433  ? 183  PHE A CE1   1 
ATOM   2724 C  CE2   . PHE A 1 192 ? 7.76294   -2.34064  27.35046 1.000 60.23539  ? 183  PHE A CE2   1 
ATOM   2725 C  CZ    . PHE A 1 192 ? 7.70319   -2.29439  25.97369 1.000 57.97276  ? 183  PHE A CZ    1 
ATOM   2726 H  H     . PHE A 1 192 ? 12.20933  -0.19273  26.78158 1.000 58.16127  ? 183  PHE A H     1 
ATOM   2727 H  HA    . PHE A 1 192 ? 10.48066  1.72206   26.56357 1.000 64.19283  ? 183  PHE A HA    1 
ATOM   2728 H  HB2   . PHE A 1 192 ? 10.87756  -0.13402  28.64660 1.000 63.64857  ? 183  PHE A HB2   1 
ATOM   2729 H  HB3   . PHE A 1 192 ? 9.69701   0.92767   28.71381 1.000 63.64857  ? 183  PHE A HB3   1 
ATOM   2730 H  HD1   . PHE A 1 192 ? 9.80618   0.11159   25.50349 1.000 69.60015  ? 183  PHE A HD1   1 
ATOM   2731 H  HD2   . PHE A 1 192 ? 8.62500   -1.50434  28.96539 1.000 74.52534  ? 183  PHE A HD2   1 
ATOM   2732 H  HE1   . PHE A 1 192 ? 8.43129   -1.34684  24.35533 1.000 72.12041  ? 183  PHE A HE1   1 
ATOM   2733 H  HE2   . PHE A 1 192 ? 7.24753   -2.95770  27.81789 1.000 72.32568  ? 183  PHE A HE2   1 
ATOM   2734 H  HZ    . PHE A 1 192 ? 7.14755   -2.87958  25.51140 1.000 69.61053  ? 183  PHE A HZ    1 
ATOM   2735 N  N     . ALA A 1 193 ? 12.51925  2.21445   29.01173 1.000 47.09895  ? 184  ALA A N     1 
ATOM   2736 C  CA    . ALA A 1 193 ? 12.91098  3.21271   29.99959 1.000 52.34674  ? 184  ALA A CA    1 
ATOM   2737 C  C     . ALA A 1 193 ? 13.93182  4.20378   29.45039 1.000 51.03892  ? 184  ALA A C     1 
ATOM   2738 O  O     . ALA A 1 193 ? 13.85285  5.40089   29.74666 1.000 50.85848  ? 184  ALA A O     1 
ATOM   2739 C  CB    . ALA A 1 193 ? 13.46484  2.52058   31.24692 1.000 64.44463  ? 184  ALA A CB    1 
ATOM   2740 H  H     . ALA A 1 193 ? 12.91348  1.45423   29.09074 1.000 56.56196  ? 184  ALA A H     1 
ATOM   2741 H  HA    . ALA A 1 193 ? 12.12138  3.71696   30.25092 1.000 62.85930  ? 184  ALA A HA    1 
ATOM   2742 H  HB1   . ALA A 1 193 ? 13.72988  3.19553   31.89119 1.000 77.37677  ? 184  ALA A HB1   1 
ATOM   2743 H  HB2   . ALA A 1 193 ? 12.77494  1.95399   31.62629 1.000 77.37677  ? 184  ALA A HB2   1 
ATOM   2744 H  HB3   . ALA A 1 193 ? 14.23260  1.98369   30.99552 1.000 77.37677  ? 184  ALA A HB3   1 
ATOM   2745 N  N     . CYS A 1 194 ? 14.88763  3.73654   28.64779 1.000 52.48208  ? 185  CYS A N     1 
ATOM   2746 C  CA    . CYS A 1 194 ? 16.03850  4.54904   28.27612 1.000 52.78448  ? 185  CYS A CA    1 
ATOM   2747 C  C     . CYS A 1 194 ? 15.98164  5.10093   26.85758 1.000 50.67440  ? 185  CYS A C     1 
ATOM   2748 O  O     . CYS A 1 194 ? 16.76846  5.99776   26.53396 1.000 51.86588  ? 185  CYS A O     1 
ATOM   2749 C  CB    . CYS A 1 194 ? 17.32722  3.73556   28.45135 1.000 53.12630  ? 185  CYS A CB    1 
ATOM   2750 S  SG    . CYS A 1 194 ? 17.84629  3.60210   30.17323 1.000 65.18984  ? 185  CYS A SG    1 
ATOM   2751 H  H     . CYS A 1 194 ? 14.88956  2.94764   28.30538 1.000 63.02171  ? 185  CYS A H     1 
ATOM   2752 H  HA    . CYS A 1 194 ? 16.07289  5.31292   28.87296 1.000 63.38459  ? 185  CYS A HA    1 
ATOM   2753 H  HB2   . CYS A 1 194 ? 17.18189  2.83861   28.11184 1.000 63.79478  ? 185  CYS A HB2   1 
ATOM   2754 H  HB3   . CYS A 1 194 ? 18.04118  4.16627   27.95572 1.000 63.79478  ? 185  CYS A HB3   1 
ATOM   2755 H  HG    . CYS A 1 194 ? 18.86241  2.96600   30.22678 1.000 78.27102  ? 185  CYS A HG    1 
ATOM   2756 N  N     . VAL A 1 195 ? 15.08478  4.60472   26.00555 1.000 48.66129  ? 186  VAL A N     1 
ATOM   2757 C  CA    . VAL A 1 195 ? 14.93866  5.10057   24.64211 1.000 56.13329  ? 186  VAL A CA    1 
ATOM   2758 C  C     . VAL A 1 195 ? 13.56790  5.72948   24.42211 1.000 55.83525  ? 186  VAL A C     1 
ATOM   2759 O  O     . VAL A 1 195 ? 13.46161  6.88242   23.99094 1.000 48.08935  ? 186  VAL A O     1 
ATOM   2760 C  CB    . VAL A 1 195 ? 15.19601  3.98417   23.60470 1.000 50.04674  ? 186  VAL A CB    1 
ATOM   2761 C  CG1   . VAL A 1 195 ? 14.93414  4.49760   22.19386 1.000 49.21757  ? 186  VAL A CG1   1 
ATOM   2762 C  CG2   . VAL A 1 195 ? 16.61904  3.46560   23.72117 1.000 53.43280  ? 186  VAL A CG2   1 
ATOM   2763 H  H     . VAL A 1 195 ? 14.54052  3.96813   26.20084 1.000 58.43676  ? 186  VAL A H     1 
ATOM   2764 H  HA    . VAL A 1 195 ? 15.60398  5.79192   24.49968 1.000 67.40316  ? 186  VAL A HA    1 
ATOM   2765 H  HB    . VAL A 1 195 ? 14.58836  3.24892   23.78095 1.000 60.09931  ? 186  VAL A HB    1 
ATOM   2766 H  HG11  . VAL A 1 195 ? 15.27637  3.85321   21.55470 1.000 59.10430  ? 186  VAL A HG11  1 
ATOM   2767 H  HG12  . VAL A 1 195 ? 13.97854  4.60991   22.07097 1.000 59.10430  ? 186  VAL A HG12  1 
ATOM   2768 H  HG13  . VAL A 1 195 ? 15.38473  5.34887   22.07889 1.000 59.10430  ? 186  VAL A HG13  1 
ATOM   2769 H  HG21  . VAL A 1 195 ? 16.72149  2.69221   23.14474 1.000 64.16258  ? 186  VAL A HG21  1 
ATOM   2770 H  HG22  . VAL A 1 195 ? 17.23334  4.16503   23.44855 1.000 64.16258  ? 186  VAL A HG22  1 
ATOM   2771 H  HG23  . VAL A 1 195 ? 16.78980  3.21613   24.64285 1.000 64.16258  ? 186  VAL A HG23  1 
ATOM   2772 N  N     . LEU A 1 196 ? 12.50243  4.98579   24.72023 1.000 53.97714  ? 187  LEU A N     1 
ATOM   2773 C  CA    . LEU A 1 196 ? 11.16299  5.45848   24.38856 1.000 54.83953  ? 187  LEU A CA    1 
ATOM   2774 C  C     . LEU A 1 196 ? 10.74506  6.61440   25.28904 1.000 56.36473  ? 187  LEU A C     1 
ATOM   2775 O  O     . LEU A 1 196 ? 10.16890  7.59930   24.81198 1.000 55.16006  ? 187  LEU A O     1 
ATOM   2776 C  CB    . LEU A 1 196 ? 10.17238  4.29965   24.48269 1.000 54.82679  ? 187  LEU A CB    1 
ATOM   2777 C  CG    . LEU A 1 196 ? 8.78670   4.48304   23.86320 1.000 62.25427  ? 187  LEU A CG    1 
ATOM   2778 C  CD1   . LEU A 1 196 ? 8.85143   5.17237   22.51388 1.000 63.09746  ? 187  LEU A CD1   1 
ATOM   2779 C  CD2   . LEU A 1 196 ? 8.11827   3.12032   23.72039 1.000 71.01982  ? 187  LEU A CD2   1 
ATOM   2780 H  H     . LEU A 1 196 ? 12.52837  4.21825   25.10726 1.000 64.81578  ? 187  LEU A H     1 
ATOM   2781 H  HA    . LEU A 1 196 ? 11.15568  5.78449   23.47502 1.000 65.85065  ? 187  LEU A HA    1 
ATOM   2782 H  HB2   . LEU A 1 196 ? 10.57381  3.53346   24.04371 1.000 65.83537  ? 187  LEU A HB2   1 
ATOM   2783 H  HB3   . LEU A 1 196 ? 10.03307  4.10777   25.42326 1.000 65.83537  ? 187  LEU A HB3   1 
ATOM   2784 H  HG    . LEU A 1 196 ? 8.25928   5.05177   24.44568 1.000 74.74834  ? 187  LEU A HG    1 
ATOM   2785 H  HD11  . LEU A 1 196 ? 7.98735   5.09795   22.07946 1.000 75.76017  ? 187  LEU A HD11  1 
ATOM   2786 H  HD12  . LEU A 1 196 ? 9.07534   6.10674   22.64701 1.000 75.76017  ? 187  LEU A HD12  1 
ATOM   2787 H  HD13  . LEU A 1 196 ? 9.53204   4.74305   21.97225 1.000 75.76017  ? 187  LEU A HD13  1 
ATOM   2788 H  HD21  . LEU A 1 196 ? 7.23673   3.23993   23.33375 1.000 85.26700  ? 187  LEU A HD21  1 
ATOM   2789 H  HD22  . LEU A 1 196 ? 8.66035   2.56179   23.14151 1.000 85.26700  ? 187  LEU A HD22  1 
ATOM   2790 H  HD23  . LEU A 1 196 ? 8.04235   2.71238   24.59715 1.000 85.26700  ? 187  LEU A HD23  1 
ATOM   2791 N  N     . VAL A 1 197 ? 11.03234  6.52426   26.58922 1.000 51.26232  ? 188  VAL A N     1 
ATOM   2792 C  CA    . VAL A 1 197 ? 10.67329  7.61135   27.50079 1.000 59.19488  ? 188  VAL A CA    1 
ATOM   2793 C  C     . VAL A 1 197 ? 11.36426  8.91515   27.10571 1.000 55.61511  ? 188  VAL A C     1 
ATOM   2794 O  O     . VAL A 1 197 ? 10.67086  9.93115   26.94665 1.000 54.92008  ? 188  VAL A O     1 
ATOM   2795 C  CB    . VAL A 1 197 ? 10.95922  7.20419   28.95263 1.000 61.79530  ? 188  VAL A CB    1 
ATOM   2796 C  CG1   . VAL A 1 197 ? 11.02056  8.43076   29.85997 1.000 58.75358  ? 188  VAL A CG1   1 
ATOM   2797 C  CG2   . VAL A 1 197 ? 9.89473   6.23275   29.44777 1.000 62.15626  ? 188  VAL A CG2   1 
ATOM   2798 H  H     . VAL A 1 197 ? 11.42706  5.85746   26.96229 1.000 61.55800  ? 188  VAL A H     1 
ATOM   2799 H  HA    . VAL A 1 197 ? 9.71567   7.74875   27.43012 1.000 71.07707  ? 188  VAL A HA    1 
ATOM   2800 H  HB    . VAL A 1 197 ? 11.82220  6.76258   28.98659 1.000 74.19757  ? 188  VAL A HB    1 
ATOM   2801 H  HG11  . VAL A 1 197 ? 10.96750  8.14254   30.78464 1.000 70.54751  ? 188  VAL A HG11  1 
ATOM   2802 H  HG12  . VAL A 1 197 ? 11.85771  8.89592   29.70600 1.000 70.54751  ? 188  VAL A HG12  1 
ATOM   2803 H  HG13  . VAL A 1 197 ? 10.27453  9.01487   29.65223 1.000 70.54751  ? 188  VAL A HG13  1 
ATOM   2804 H  HG21  . VAL A 1 197 ? 10.11174  5.96116   30.35334 1.000 74.63073  ? 188  VAL A HG21  1 
ATOM   2805 H  HG22  . VAL A 1 197 ? 9.03178   6.67546   29.43303 1.000 74.63073  ? 188  VAL A HG22  1 
ATOM   2806 H  HG23  . VAL A 1 197 ? 9.87885   5.45764   28.86480 1.000 74.63073  ? 188  VAL A HG23  1 
ATOM   2807 N  N     . PRO A 1 198 ? 12.68984  8.96277   26.94218 1.000 52.15364  ? 189  PRO A N     1 
ATOM   2808 C  CA    . PRO A 1 198 ? 13.30882  10.20639  26.45191 1.000 54.46248  ? 189  PRO A CA    1 
ATOM   2809 C  C     . PRO A 1 198 ? 12.69168  10.71894  25.16033 1.000 57.51494  ? 189  PRO A C     1 
ATOM   2810 O  O     . PRO A 1 198 ? 12.47407  11.92886  25.02293 1.000 51.46103  ? 189  PRO A O     1 
ATOM   2811 C  CB    . PRO A 1 198 ? 14.78068  9.80958   26.26480 1.000 54.62905  ? 189  PRO A CB    1 
ATOM   2812 C  CG    . PRO A 1 198 ? 15.00003  8.70619   27.22980 1.000 54.06649  ? 189  PRO A CG    1 
ATOM   2813 C  CD    . PRO A 1 198 ? 13.69545  7.95458   27.32272 1.000 55.33982  ? 189  PRO A CD    1 
ATOM   2814 H  HA    . PRO A 1 198 ? 13.24672  10.89508  27.13216 1.000 65.39819  ? 189  PRO A HA    1 
ATOM   2815 H  HB2   . PRO A 1 198 ? 14.92972  9.51030   25.35424 1.000 65.59808  ? 189  PRO A HB2   1 
ATOM   2816 H  HB3   . PRO A 1 198 ? 15.35522  10.56534  26.46386 1.000 65.59808  ? 189  PRO A HB3   1 
ATOM   2817 H  HG2   . PRO A 1 198 ? 15.70595  8.12585   26.90456 1.000 64.92300  ? 189  PRO A HG2   1 
ATOM   2818 H  HG3   . PRO A 1 198 ? 15.24441  9.07392   28.09349 1.000 64.92300  ? 189  PRO A HG3   1 
ATOM   2819 H  HD2   . PRO A 1 198 ? 13.68411  7.20659   26.70524 1.000 66.45100  ? 189  PRO A HD2   1 
ATOM   2820 H  HD3   . PRO A 1 198 ? 13.54274  7.64016   28.22755 1.000 66.45100  ? 189  PRO A HD3   1 
ATOM   2821 N  N     . LEU A 1 199 ? 12.39324  9.83133   24.20866 1.000 53.16775  ? 190  LEU A N     1 
ATOM   2822 C  CA    . LEU A 1 199 ? 11.83206  10.28332  22.93922 1.000 56.17453  ? 190  LEU A CA    1 
ATOM   2823 C  C     . LEU A 1 199 ? 10.47010  10.93690  23.14131 1.000 56.32808  ? 190  LEU A C     1 
ATOM   2824 O  O     . LEU A 1 199 ? 10.19461  12.00106  22.57488 1.000 56.14113  ? 190  LEU A O     1 
ATOM   2825 C  CB    . LEU A 1 199 ? 11.73997  9.11202   21.96156 1.000 63.74991  ? 190  LEU A CB    1 
ATOM   2826 C  CG    . LEU A 1 199 ? 13.07858  8.66627   21.36538 1.000 57.97548  ? 190  LEU A CG    1 
ATOM   2827 C  CD1   . LEU A 1 199 ? 12.97144  7.27881   20.74895 1.000 58.29088  ? 190  LEU A CD1   1 
ATOM   2828 C  CD2   . LEU A 1 199 ? 13.56176  9.67027   20.32893 1.000 60.85576  ? 190  LEU A CD2   1 
ATOM   2829 H  H     . LEU A 1 199 ? 12.50414  8.98093   24.27290 1.000 63.84452  ? 190  LEU A H     1 
ATOM   2830 H  HA    . LEU A 1 199 ? 12.42296  10.94678  22.54991 1.000 67.45265  ? 190  LEU A HA    1 
ATOM   2831 H  HB2   . LEU A 1 199 ? 11.36008  8.35138   22.42847 1.000 76.54311  ? 190  LEU A HB2   1 
ATOM   2832 H  HB3   . LEU A 1 199 ? 11.16381  9.37098   21.22543 1.000 76.54311  ? 190  LEU A HB3   1 
ATOM   2833 H  HG    . LEU A 1 199 ? 13.73369  8.62282   22.07941 1.000 69.61379  ? 190  LEU A HG    1 
ATOM   2834 H  HD11  . LEU A 1 199 ? 13.82978  7.03516   20.36844 1.000 69.99228  ? 190  LEU A HD11  1 
ATOM   2835 H  HD12  . LEU A 1 199 ? 12.72387  6.64455   21.43984 1.000 69.99228  ? 190  LEU A HD12  1 
ATOM   2836 H  HD13  . LEU A 1 199 ? 12.29398  7.29306   20.05487 1.000 69.99228  ? 190  LEU A HD13  1 
ATOM   2837 H  HD21  . LEU A 1 199 ? 14.40004  9.35816   19.95373 1.000 73.07013  ? 190  LEU A HD21  1 
ATOM   2838 H  HD22  . LEU A 1 199 ? 12.89456  9.74758   19.62910 1.000 73.07013  ? 190  LEU A HD22  1 
ATOM   2839 H  HD23  . LEU A 1 199 ? 13.69151  10.53013  20.75870 1.000 73.07013  ? 190  LEU A HD23  1 
ATOM   2840 N  N     . LEU A 1 200 ? 9.60554   10.32193  23.95362 1.000 56.18268  ? 191  LEU A N     1 
ATOM   2841 C  CA    . LEU A 1 200 ? 8.31534   10.93770  24.24790 1.000 55.21624  ? 191  LEU A CA    1 
ATOM   2842 C  C     . LEU A 1 200 ? 8.49283   12.27346  24.95798 1.000 57.11873  ? 191  LEU A C     1 
ATOM   2843 O  O     . LEU A 1 200 ? 7.70587   13.20469  24.74340 1.000 54.00069  ? 191  LEU A O     1 
ATOM   2844 C  CB    . LEU A 1 200 ? 7.46553   9.99021   25.09440 1.000 57.61223  ? 191  LEU A CB    1 
ATOM   2845 C  CG    . LEU A 1 200 ? 7.05664   8.68388   24.41065 1.000 56.97050  ? 191  LEU A CG    1 
ATOM   2846 C  CD1   . LEU A 1 200 ? 6.33060   7.77453   25.38626 1.000 56.97649  ? 191  LEU A CD1   1 
ATOM   2847 C  CD2   . LEU A 1 200 ? 6.18901   8.95274   23.19172 1.000 61.62302  ? 191  LEU A CD2   1 
ATOM   2848 H  H     . LEU A 1 200 ? 9.74069   9.56440   24.33764 1.000 67.46243  ? 191  LEU A H     1 
ATOM   2849 H  HA    . LEU A 1 200 ? 7.84209   11.09829  23.41655 1.000 66.30270  ? 191  LEU A HA    1 
ATOM   2850 H  HB2   . LEU A 1 200 ? 7.97074   9.75542   25.88847 1.000 69.17789  ? 191  LEU A HB2   1 
ATOM   2851 H  HB3   . LEU A 1 200 ? 6.65073   10.45332  25.34447 1.000 69.17789  ? 191  LEU A HB3   1 
ATOM   2852 H  HG    . LEU A 1 200 ? 7.85933   8.22997   24.10971 1.000 68.40781  ? 191  LEU A HG    1 
ATOM   2853 H  HD11  . LEU A 1 200 ? 6.07148   6.96071   24.92641 1.000 68.41500  ? 191  LEU A HD11  1 
ATOM   2854 H  HD12  . LEU A 1 200 ? 6.92495   7.56319   26.12312 1.000 68.41500  ? 191  LEU A HD12  1 
ATOM   2855 H  HD13  . LEU A 1 200 ? 5.54237   8.23235   25.71792 1.000 68.41500  ? 191  LEU A HD13  1 
ATOM   2856 H  HD21  . LEU A 1 200 ? 5.84253   8.11017   22.85866 1.000 73.99083  ? 191  LEU A HD21  1 
ATOM   2857 H  HD22  . LEU A 1 200 ? 5.45577   9.53378   23.44796 1.000 73.99083  ? 191  LEU A HD22  1 
ATOM   2858 H  HD23  . LEU A 1 200 ? 6.72799   9.38183   22.50888 1.000 73.99083  ? 191  LEU A HD23  1 
ATOM   2859 N  N     . LEU A 1 201 ? 9.51505   12.38634  25.80629 1.000 55.92043  ? 192  LEU A N     1 
ATOM   2860 C  CA    . LEU A 1 201 ? 9.82529   13.67236  26.42087 1.000 57.47039  ? 192  LEU A CA    1 
ATOM   2861 C  C     . LEU A 1 201 ? 10.20230  14.70190  25.36308 1.000 53.98917  ? 192  LEU A C     1 
ATOM   2862 O  O     . LEU A 1 201 ? 9.71743   15.83827  25.38707 1.000 57.47398  ? 192  LEU A O     1 
ATOM   2863 C  CB    . LEU A 1 201 ? 10.95238  13.50857  27.43954 1.000 59.33291  ? 192  LEU A CB    1 
ATOM   2864 C  CG    . LEU A 1 201 ? 10.51692  13.09587  28.84360 1.000 57.32953  ? 192  LEU A CG    1 
ATOM   2865 C  CD1   . LEU A 1 201 ? 11.67274  12.45710  29.59356 1.000 57.36145  ? 192  LEU A CD1   1 
ATOM   2866 C  CD2   . LEU A 1 201 ? 9.98533   14.30168  29.60292 1.000 65.86086  ? 192  LEU A CD2   1 
ATOM   2867 H  H     . LEU A 1 201 ? 10.03595  11.74266  26.03852 1.000 67.14773  ? 192  LEU A H     1 
ATOM   2868 H  HA    . LEU A 1 201 ? 9.04036   13.99339  26.89175 1.000 69.00769  ? 192  LEU A HA    1 
ATOM   2869 H  HB2   . LEU A 1 201 ? 11.56033  12.82673  27.11336 1.000 71.24271  ? 192  LEU A HB2   1 
ATOM   2870 H  HB3   . LEU A 1 201 ? 11.41653  14.35664  27.51846 1.000 71.24271  ? 192  LEU A HB3   1 
ATOM   2871 H  HG    . LEU A 1 201 ? 9.80550   12.43973  28.77838 1.000 68.83866  ? 192  LEU A HG    1 
ATOM   2872 H  HD11  . LEU A 1 201 ? 11.37398  12.20944  30.48255 1.000 68.87695  ? 192  LEU A HD11  1 
ATOM   2873 H  HD12  . LEU A 1 201 ? 11.96473  11.66799  29.11092 1.000 68.87695  ? 192  LEU A HD12  1 
ATOM   2874 H  HD13  . LEU A 1 201 ? 12.40054  13.09540  29.65504 1.000 68.87695  ? 192  LEU A HD13  1 
ATOM   2875 H  HD21  . LEU A 1 201 ? 9.71268   14.02090  30.49046 1.000 79.07624  ? 192  LEU A HD21  1 
ATOM   2876 H  HD22  . LEU A 1 201 ? 10.68687  14.96840  29.66784 1.000 79.07624  ? 192  LEU A HD22  1 
ATOM   2877 H  HD23  . LEU A 1 201 ? 9.22529   14.66686  29.12345 1.000 79.07624  ? 192  LEU A HD23  1 
ATOM   2878 N  N     . MET A 1 202 ? 11.07632  14.32224  24.42583 1.000 57.69734  ? 193  MET A N     1 
ATOM   2879 C  CA    . MET A 1 202 ? 11.40806  15.22106  23.32518 1.000 57.67587  ? 193  MET A CA    1 
ATOM   2880 C  C     . MET A 1 202 ? 10.15135  15.65883  22.58618 1.000 57.35368  ? 193  MET A C     1 
ATOM   2881 O  O     . MET A 1 202 ? 9.99586   16.83924  22.25326 1.000 57.60054  ? 193  MET A O     1 
ATOM   2882 C  CB    . MET A 1 202 ? 12.37999  14.54144  22.36029 1.000 56.20839  ? 193  MET A CB    1 
ATOM   2883 C  CG    . MET A 1 202 ? 13.79760  14.41384  22.88398 1.000 59.80574  ? 193  MET A CG    1 
ATOM   2884 S  SD    . MET A 1 202 ? 14.81858  13.37037  21.82498 1.000 62.17427  ? 193  MET A SD    1 
ATOM   2885 C  CE    . MET A 1 202 ? 15.71701  12.42726  23.05832 1.000 60.17640  ? 193  MET A CE    1 
ATOM   2886 H  H     . MET A 1 202 ? 11.48182  13.56408  24.40671 1.000 69.28002  ? 193  MET A H     1 
ATOM   2887 H  HA    . MET A 1 202 ? 11.85269  16.00247  23.68934 1.000 69.25425  ? 193  MET A HA    1 
ATOM   2888 H  HB2   . MET A 1 202 ? 12.05492  13.64692  22.17305 1.000 67.49329  ? 193  MET A HB2   1 
ATOM   2889 H  HB3   . MET A 1 202 ? 12.41552  15.05975  21.54115 1.000 67.49329  ? 193  MET A HB3   1 
ATOM   2890 H  HG2   . MET A 1 202 ? 14.20323  15.29405  22.92385 1.000 71.81010  ? 193  MET A HG2   1 
ATOM   2891 H  HG3   . MET A 1 202 ? 13.77606  14.01806  23.76930 1.000 71.81010  ? 193  MET A HG3   1 
ATOM   2892 H  HE1   . MET A 1 202 ? 16.11795  11.65291  22.63344 1.000 72.25490  ? 193  MET A HE1   1 
ATOM   2893 H  HE2   . MET A 1 202 ? 16.40833  12.98842  23.44313 1.000 72.25490  ? 193  MET A HE2   1 
ATOM   2894 H  HE3   . MET A 1 202 ? 15.09926  12.14236  23.74978 1.000 72.25490  ? 193  MET A HE3   1 
ATOM   2895 N  N     . LEU A 1 203 ? 9.23981   14.71911  22.32593 1.000 58.48331  ? 194  LEU A N     1 
ATOM   2896 C  CA    . LEU A 1 203 ? 7.99333   15.06010  21.64841 1.000 58.88081  ? 194  LEU A CA    1 
ATOM   2897 C  C     . LEU A 1 203 ? 7.24396   16.14777  22.40673 1.000 58.81304  ? 194  LEU A C     1 
ATOM   2898 O  O     . LEU A 1 203 ? 6.79309   17.13622  21.81666 1.000 57.85442  ? 194  LEU A O     1 
ATOM   2899 C  CB    . LEU A 1 203 ? 7.12493   13.81087  21.49803 1.000 59.65153  ? 194  LEU A CB    1 
ATOM   2900 C  CG    . LEU A 1 203 ? 5.82523   13.98119  20.71167 1.000 58.66899  ? 194  LEU A CG    1 
ATOM   2901 C  CD1   . LEU A 1 203 ? 6.10681   14.36908  19.26885 1.000 67.53816  ? 194  LEU A CD1   1 
ATOM   2902 C  CD2   . LEU A 1 203 ? 5.00978   12.70127  20.77104 1.000 61.88730  ? 194  LEU A CD2   1 
ATOM   2903 H  H     . LEU A 1 203 ? 9.31944   13.88734  22.52943 1.000 70.22319  ? 194  LEU A H     1 
ATOM   2904 H  HA    . LEU A 1 203 ? 8.19659   15.39477  20.76095 1.000 70.70019  ? 194  LEU A HA    1 
ATOM   2905 H  HB2   . LEU A 1 203 ? 7.64827   13.13314  21.04230 1.000 71.62505  ? 194  LEU A HB2   1 
ATOM   2906 H  HB3   . LEU A 1 203 ? 6.88394   13.50275  22.38565 1.000 71.62505  ? 194  LEU A HB3   1 
ATOM   2907 H  HG    . LEU A 1 203 ? 5.30655   14.69716  21.11074 1.000 70.44601  ? 194  LEU A HG    1 
ATOM   2908 H  HD11  . LEU A 1 203 ? 5.26512   14.44979  18.79351 1.000 81.08900  ? 194  LEU A HD11  1 
ATOM   2909 H  HD12  . LEU A 1 203 ? 6.57669   15.21758  19.25589 1.000 81.08900  ? 194  LEU A HD12  1 
ATOM   2910 H  HD13  . LEU A 1 203 ? 6.65408   13.68159  18.85806 1.000 81.08900  ? 194  LEU A HD13  1 
ATOM   2911 H  HD21  . LEU A 1 203 ? 4.18838   12.82664  20.27055 1.000 74.30797  ? 194  LEU A HD21  1 
ATOM   2912 H  HD22  . LEU A 1 203 ? 5.52717   11.97886  20.38202 1.000 74.30797  ? 194  LEU A HD22  1 
ATOM   2913 H  HD23  . LEU A 1 203 ? 4.80512   12.49990  21.69757 1.000 74.30797  ? 194  LEU A HD23  1 
ATOM   2914 N  N     . GLY A 1 204 ? 7.10485   15.98172  23.72275 1.000 58.83484  ? 195  GLY A N     1 
ATOM   2915 C  CA    . GLY A 1 204 ? 6.44029   16.99937  24.51793 1.000 59.24311  ? 195  GLY A CA    1 
ATOM   2916 C  C     . GLY A 1 204 ? 7.17423   18.32584  24.49932 1.000 59.47728  ? 195  GLY A C     1 
ATOM   2917 O  O     . GLY A 1 204 ? 6.55229   19.39008  24.44056 1.000 61.17385  ? 195  GLY A O     1 
ATOM   2918 H  H     . GLY A 1 204 ? 7.38255   15.30017  24.16769 1.000 70.64502  ? 195  GLY A H     1 
ATOM   2919 H  HA2   . GLY A 1 204 ? 5.54514   17.14156  24.17240 1.000 71.13494  ? 195  GLY A HA2   1 
ATOM   2920 H  HA3   . GLY A 1 204 ? 6.37950   16.69766  25.43781 1.000 71.13494  ? 195  GLY A HA3   1 
ATOM   2921 N  N     . VAL A 1 205 ? 8.50680   18.28340  24.55065 1.000 57.55847  ? 196  VAL A N     1 
ATOM   2922 C  CA    . VAL A 1 205 ? 9.28516   19.51886  24.52421 1.000 62.57316  ? 196  VAL A CA    1 
ATOM   2923 C  C     . VAL A 1 205 ? 9.01940   20.27790  23.23051 1.000 63.37781  ? 196  VAL A C     1 
ATOM   2924 O  O     . VAL A 1 205 ? 8.72704   21.47942  23.24257 1.000 66.30742  ? 196  VAL A O     1 
ATOM   2925 C  CB    . VAL A 1 205 ? 10.78376  19.21614  24.70522 1.000 62.50007  ? 196  VAL A CB    1 
ATOM   2926 C  CG1   . VAL A 1 205 ? 11.62287  20.46205  24.43281 1.000 67.13335  ? 196  VAL A CG1   1 
ATOM   2927 C  CG2   . VAL A 1 205 ? 11.05275  18.69342  26.10797 1.000 54.74640  ? 196  VAL A CG2   1 
ATOM   2928 H  H     . VAL A 1 205 ? 8.97549   17.56405  24.60023 1.000 69.11338  ? 196  VAL A H     1 
ATOM   2929 H  HA    . VAL A 1 205 ? 9.00377   20.07833  25.26496 1.000 75.13101  ? 196  VAL A HA    1 
ATOM   2930 H  HB    . VAL A 1 205 ? 11.04229  18.53254  24.06744 1.000 75.04330  ? 196  VAL A HB    1 
ATOM   2931 H  HG11  . VAL A 1 205 ? 12.52472  20.31253  24.75715 1.000 80.60323  ? 196  VAL A HG11  1 
ATOM   2932 H  HG12  . VAL A 1 205 ? 11.63844  20.62965  23.47753 1.000 80.60323  ? 196  VAL A HG12  1 
ATOM   2933 H  HG13  . VAL A 1 205 ? 11.22618  21.21716  24.89470 1.000 80.60323  ? 196  VAL A HG13  1 
ATOM   2934 H  HG21  . VAL A 1 205 ? 11.99909  18.49990  26.19679 1.000 65.73890  ? 196  VAL A HG21  1 
ATOM   2935 H  HG22  . VAL A 1 205 ? 10.79150  19.36964  26.75246 1.000 65.73890  ? 196  VAL A HG22  1 
ATOM   2936 H  HG23  . VAL A 1 205 ? 10.53523  17.88513  26.24842 1.000 65.73890  ? 196  VAL A HG23  1 
ATOM   2937 N  N     . TYR A 1 206 ? 9.10197   19.58209  22.09310 1.000 61.50732  ? 197  TYR A N     1 
ATOM   2938 C  CA    . TYR A 1 206 ? 8.90725   20.24659  20.80896 1.000 62.76288  ? 197  TYR A CA    1 
ATOM   2939 C  C     . TYR A 1 206 ? 7.47152   20.72169  20.62749 1.000 65.89736  ? 197  TYR A C     1 
ATOM   2940 O  O     . TYR A 1 206 ? 7.23776   21.72412  19.94304 1.000 68.73596  ? 197  TYR A O     1 
ATOM   2941 C  CB    . TYR A 1 206 ? 9.31371   19.31496  19.66736 1.000 64.41825  ? 197  TYR A CB    1 
ATOM   2942 C  CG    . TYR A 1 206 ? 10.81094  19.23902  19.47860 1.000 64.83856  ? 197  TYR A CG    1 
ATOM   2943 C  CD1   . TYR A 1 206 ? 11.52433  20.33479  19.00845 1.000 67.62800  ? 197  TYR A CD1   1 
ATOM   2944 C  CD2   . TYR A 1 206 ? 11.51286  18.07911  19.77587 1.000 59.05593  ? 197  TYR A CD2   1 
ATOM   2945 C  CE1   . TYR A 1 206 ? 12.89402  20.27771  18.83940 1.000 66.70043  ? 197  TYR A CE1   1 
ATOM   2946 C  CE2   . TYR A 1 206 ? 12.88333  18.01140  19.60870 1.000 58.88655  ? 197  TYR A CE2   1 
ATOM   2947 C  CZ    . TYR A 1 206 ? 13.56887  19.11404  19.14052 1.000 64.07656  ? 197  TYR A CZ    1 
ATOM   2948 O  OH    . TYR A 1 206 ? 14.93379  19.05826  18.97089 1.000 64.79823  ? 197  TYR A OH    1 
ATOM   2949 H  H     . TYR A 1 206 ? 9.26670   18.73963  22.04085 1.000 73.85200  ? 197  TYR A H     1 
ATOM   2950 H  HA    . TYR A 1 206 ? 9.48160   21.02750  20.77416 1.000 75.35867  ? 197  TYR A HA    1 
ATOM   2951 H  HB2   . TYR A 1 206 ? 8.98959   18.42101  19.85896 1.000 77.34512  ? 197  TYR A HB2   1 
ATOM   2952 H  HB3   . TYR A 1 206 ? 8.92305   19.63946  18.84093 1.000 77.34512  ? 197  TYR A HB3   1 
ATOM   2953 H  HD1   . TYR A 1 206 ? 11.07140  21.12086  18.80388 1.000 81.19681  ? 197  TYR A HD1   1 
ATOM   2954 H  HD2   . TYR A 1 206 ? 11.05352  17.33515  20.09277 1.000 70.91034  ? 197  TYR A HD2   1 
ATOM   2955 H  HE1   . TYR A 1 206 ? 13.35799  21.01962  18.52443 1.000 80.08374  ? 197  TYR A HE1   1 
ATOM   2956 H  HE2   . TYR A 1 206 ? 13.34087  17.22731  19.81056 1.000 70.70708  ? 197  TYR A HE2   1 
ATOM   2957 H  HH    . TYR A 1 206 ? 15.21751  18.29410  19.17377 1.000 77.80110  ? 197  TYR A HH    1 
ATOM   2958 N  N     . LEU A 1 207 ? 6.49927   20.02649  21.22067 1.000 64.65950  ? 198  LEU A N     1 
ATOM   2959 C  CA    . LEU A 1 207 ? 5.13269   20.53823  21.21303 1.000 66.33271  ? 198  LEU A CA    1 
ATOM   2960 C  C     . LEU A 1 207 ? 5.04896   21.85121  21.98317 1.000 67.01975  ? 198  LEU A C     1 
ATOM   2961 O  O     . LEU A 1 207 ? 4.43132   22.81782  21.52192 1.000 71.50690  ? 198  LEU A O     1 
ATOM   2962 C  CB    . LEU A 1 207 ? 4.17124   19.50438  21.79980 1.000 65.58348  ? 198  LEU A CB    1 
ATOM   2963 C  CG    . LEU A 1 207 ? 3.84074   18.29039  20.92758 1.000 66.72580  ? 198  LEU A CG    1 
ATOM   2964 C  CD1   . LEU A 1 207 ? 2.80225   17.41860  21.62620 1.000 71.17907  ? 198  LEU A CD1   1 
ATOM   2965 C  CD2   . LEU A 1 207 ? 3.34770   18.68984  19.54397 1.000 70.14056  ? 198  LEU A CD2   1 
ATOM   2966 H  H     . LEU A 1 207 ? 6.60346   19.27428  21.62430 1.000 77.63462  ? 198  LEU A H     1 
ATOM   2967 H  HA    . LEU A 1 207 ? 4.86328   20.70035  20.29540 1.000 79.64246  ? 198  LEU A HA    1 
ATOM   2968 H  HB2   . LEU A 1 207 ? 4.56173   19.16540  22.62048 1.000 78.74340  ? 198  LEU A HB2   1 
ATOM   2969 H  HB3   . LEU A 1 207 ? 3.33229   19.95187  21.99169 1.000 78.74340  ? 198  LEU A HB3   1 
ATOM   2970 H  HG    . LEU A 1 207 ? 4.65587   17.78069  20.79849 1.000 80.11417  ? 198  LEU A HG    1 
ATOM   2971 H  HD11  . LEU A 1 207 ? 2.60242   16.65371  21.06414 1.000 85.45810  ? 198  LEU A HD11  1 
ATOM   2972 H  HD12  . LEU A 1 207 ? 3.16126   17.11964  22.47627 1.000 85.45810  ? 198  LEU A HD12  1 
ATOM   2973 H  HD13  . LEU A 1 207 ? 1.99805   17.94097  21.77210 1.000 85.45810  ? 198  LEU A HD13  1 
ATOM   2974 H  HD21  . LEU A 1 207 ? 3.08764   17.89125  19.05866 1.000 84.21189  ? 198  LEU A HD21  1 
ATOM   2975 H  HD22  . LEU A 1 207 ? 2.58536   19.28202  19.63915 1.000 84.21189  ? 198  LEU A HD22  1 
ATOM   2976 H  HD23  . LEU A 1 207 ? 4.06322   19.14486  19.07293 1.000 84.21189  ? 198  LEU A HD23  1 
ATOM   2977 N  N     . ARG A 1 208 ? 5.67111   21.90340  23.16504 1.000 65.81586  ? 199  ARG A N     1 
ATOM   2978 C  CA    . ARG A 1 208 ? 5.74211   23.15832  23.90634 1.000 67.42198  ? 199  ARG A CA    1 
ATOM   2979 C  C     . ARG A 1 208 ? 6.41892   24.24145  23.07707 1.000 69.30785  ? 199  ARG A C     1 
ATOM   2980 O  O     . ARG A 1 208 ? 5.98510   25.39921  23.07742 1.000 68.79333  ? 199  ARG A O     1 
ATOM   2981 C  CB    . ARG A 1 208 ? 6.49640   22.95395  25.22072 1.000 66.37867  ? 199  ARG A CB    1 
ATOM   2982 C  CG    . ARG A 1 208 ? 5.76596   22.11390  26.25949 1.000 68.98530  ? 199  ARG A CG    1 
ATOM   2983 C  CD    . ARG A 1 208 ? 4.78039   22.93480  27.08497 1.000 80.41768  ? 199  ARG A CD    1 
ATOM   2984 N  NE    . ARG A 1 208 ? 4.90036   22.64498  28.51121 1.000 84.54321  ? 199  ARG A NE    1 
ATOM   2985 C  CZ    . ARG A 1 208 ? 5.44042   23.45781  29.41308 1.000 87.98351  ? 199  ARG A CZ    1 
ATOM   2986 N  NH1   . ARG A 1 208 ? 5.88913   24.66029  29.08682 1.000 82.97270  ? 199  ARG A NH1   1 
ATOM   2987 N  NH2   . ARG A 1 208 ? 5.52691   23.05511  30.67789 1.000 90.85684  ? 199  ARG A NH2   1 
ATOM   2988 H  H     . ARG A 1 208 ? 6.05295   21.23649  23.55106 1.000 79.02225  ? 199  ARG A H     1 
ATOM   2989 H  HA    . ARG A 1 208 ? 4.84055   23.44738  24.11735 1.000 80.94959  ? 199  ARG A HA    1 
ATOM   2990 H  HB2   . ARG A 1 208 ? 7.33655   22.50978  25.02639 1.000 79.69763  ? 199  ARG A HB2   1 
ATOM   2991 H  HB3   . ARG A 1 208 ? 6.66458   23.82352  25.61628 1.000 79.69763  ? 199  ARG A HB3   1 
ATOM   2992 H  HG2   . ARG A 1 208 ? 5.26990   21.41256  25.80900 1.000 82.82557  ? 199  ARG A HG2   1 
ATOM   2993 H  HG3   . ARG A 1 208 ? 6.41483   21.72416  26.86609 1.000 82.82557  ? 199  ARG A HG3   1 
ATOM   2994 H  HD2   . ARG A 1 208 ? 4.95764   23.87889  26.95013 1.000 96.54443  ? 199  ARG A HD2   1 
ATOM   2995 H  HD3   . ARG A 1 208 ? 3.87545   22.72405  26.80648 1.000 96.54443  ? 199  ARG A HD3   1 
ATOM   2996 H  HE    . ARG A 1 208 ? 4.59794   21.88938  28.78909 1.000 101.49507 ? 199  ARG A HE    1 
ATOM   2997 H  HH11  . ARG A 1 208 ? 5.83498   24.93328  28.27310 1.000 99.61045  ? 199  ARG A HH11  1 
ATOM   2998 H  HH12  . ARG A 1 208 ? 6.23468   25.16821  29.68867 1.000 99.61045  ? 199  ARG A HH12  1 
ATOM   2999 H  HH21  . ARG A 1 208 ? 5.23536   22.27787  30.90259 1.000 109.07143 ? 199  ARG A HH21  1 
ATOM   3000 H  HH22  . ARG A 1 208 ? 5.87438   23.57200  31.27092 1.000 109.07143 ? 199  ARG A HH22  1 
ATOM   3001 N  N     . ILE A 1 209 ? 7.48593   23.88085  22.36092 1.000 71.15795  ? 200  ILE A N     1 
ATOM   3002 C  CA    . ILE A 1 209 ? 8.21186   24.85671  21.55147 1.000 71.38899  ? 200  ILE A CA    1 
ATOM   3003 C  C     . ILE A 1 209 ? 7.28476   25.46871  20.50992 1.000 70.79747  ? 200  ILE A C     1 
ATOM   3004 O  O     . ILE A 1 209 ? 7.09201   26.68875  20.45857 1.000 73.94043  ? 200  ILE A O     1 
ATOM   3005 C  CB    . ILE A 1 209 ? 9.44112   24.20293  20.89440 1.000 69.94370  ? 200  ILE A CB    1 
ATOM   3006 C  CG1   . ILE A 1 209 ? 10.48856  23.86830  21.95977 1.000 71.13938  ? 200  ILE A CG1   1 
ATOM   3007 C  CG2   . ILE A 1 209 ? 10.03335  25.12018  19.82890 1.000 68.01218  ? 200  ILE A CG2   1 
ATOM   3008 C  CD1   . ILE A 1 209 ? 11.69456  23.11166  21.43672 1.000 71.93663  ? 200  ILE A CD1   1 
ATOM   3009 H  H     . ILE A 1 209 ? 7.80658   23.08356  22.32750 1.000 85.43276  ? 200  ILE A H     1 
ATOM   3010 H  HA    . ILE A 1 209 ? 8.52421   25.56940  22.13062 1.000 85.71001  ? 200  ILE A HA    1 
ATOM   3011 H  HB    . ILE A 1 209 ? 9.15956   23.38049  20.46402 1.000 83.97566  ? 200  ILE A HB    1 
ATOM   3012 H  HG12  . ILE A 1 209 ? 10.80861  24.69669  22.34994 1.000 85.41047  ? 200  ILE A HG12  1 
ATOM   3013 H  HG13  . ILE A 1 209 ? 10.07137  23.31956  22.64222 1.000 85.41047  ? 200  ILE A HG13  1 
ATOM   3014 H  HG21  . ILE A 1 209 ? 10.88718  24.76049  19.54167 1.000 81.65783  ? 200  ILE A HG21  1 
ATOM   3015 H  HG22  . ILE A 1 209 ? 9.42321   25.16496  19.07616 1.000 81.65783  ? 200  ILE A HG22  1 
ATOM   3016 H  HG23  . ILE A 1 209 ? 10.15745  26.00472  20.20718 1.000 81.65783  ? 200  ILE A HG23  1 
ATOM   3017 H  HD11  . ILE A 1 209 ? 12.19290  22.75361  22.18795 1.000 86.36717  ? 200  ILE A HD11  1 
ATOM   3018 H  HD12  . ILE A 1 209 ? 11.39055  22.38825  20.86649 1.000 86.36717  ? 200  ILE A HD12  1 
ATOM   3019 H  HD13  . ILE A 1 209 ? 12.25351  23.72051  20.92901 1.000 86.36717  ? 200  ILE A HD13  1 
ATOM   3020 N  N     . PHE A 1 210 ? 6.69309   24.62349  19.66541 1.000 72.01170  ? 201  PHE A N     1 
ATOM   3021 C  CA    . PHE A 1 210 ? 5.86605   25.12802  18.57476 1.000 75.37300  ? 201  PHE A CA    1 
ATOM   3022 C  C     . PHE A 1 210 ? 4.62085   25.82656  19.10307 1.000 77.96370  ? 201  PHE A C     1 
ATOM   3023 O  O     . PHE A 1 210 ? 4.19439   26.84707  18.54976 1.000 78.19105  ? 201  PHE A O     1 
ATOM   3024 C  CB    . PHE A 1 210 ? 5.49935   23.98001  17.63699 1.000 75.13217  ? 201  PHE A CB    1 
ATOM   3025 C  CG    . PHE A 1 210 ? 6.68550   23.37302  16.94103 1.000 72.79476  ? 201  PHE A CG    1 
ATOM   3026 C  CD1   . PHE A 1 210 ? 7.57072   24.17039  16.23314 1.000 74.82374  ? 201  PHE A CD1   1 
ATOM   3027 C  CD2   . PHE A 1 210 ? 6.92886   22.01253  17.01182 1.000 75.25613  ? 201  PHE A CD2   1 
ATOM   3028 C  CE1   . PHE A 1 210 ? 8.66749   23.61996  15.59756 1.000 78.01691  ? 201  PHE A CE1   1 
ATOM   3029 C  CE2   . PHE A 1 210 ? 8.02625   21.45593  16.37893 1.000 70.65234  ? 201  PHE A CE2   1 
ATOM   3030 C  CZ    . PHE A 1 210 ? 8.89638   22.26045  15.67193 1.000 69.34992  ? 201  PHE A CZ    1 
ATOM   3031 H  H     . PHE A 1 210 ? 6.75417   23.76645  19.70228 1.000 86.45725  ? 201  PHE A H     1 
ATOM   3032 H  HA    . PHE A 1 210 ? 6.37089   25.78070  18.06482 1.000 90.49082  ? 201  PHE A HA    1 
ATOM   3033 H  HB2   . PHE A 1 210 ? 5.06719   23.28093  18.15218 1.000 90.20182  ? 201  PHE A HB2   1 
ATOM   3034 H  HB3   . PHE A 1 210 ? 4.89378   24.31312  16.95638 1.000 90.20182  ? 201  PHE A HB3   1 
ATOM   3035 H  HD1   . PHE A 1 210 ? 7.42483   25.08762  16.18519 1.000 89.83171  ? 201  PHE A HD1   1 
ATOM   3036 H  HD2   . PHE A 1 210 ? 6.34810   21.46602  17.49031 1.000 90.35057  ? 201  PHE A HD2   1 
ATOM   3037 H  HE1   . PHE A 1 210 ? 9.25080   24.16476  15.12023 1.000 93.66350  ? 201  PHE A HE1   1 
ATOM   3038 H  HE2   . PHE A 1 210 ? 8.17739   20.53972  16.43003 1.000 84.82602  ? 201  PHE A HE2   1 
ATOM   3039 H  HZ    . PHE A 1 210 ? 9.63488   21.88795  15.24677 1.000 83.26311  ? 201  PHE A HZ    1 
ATOM   3040 N  N     . ALA A 1 211 ? 4.02781   25.30069  20.17599 1.000 78.29192  ? 202  ALA A N     1 
ATOM   3041 C  CA    . ALA A 1 211 ? 2.89912   25.98438  20.79730 1.000 76.27203  ? 202  ALA A CA    1 
ATOM   3042 C  C     . ALA A 1 211 ? 3.30236   27.37946  21.25599 1.000 79.28958  ? 202  ALA A C     1 
ATOM   3043 O  O     . ALA A 1 211 ? 2.59174   28.35966  21.00423 1.000 78.01339  ? 202  ALA A O     1 
ATOM   3044 C  CB    . ALA A 1 211 ? 2.36669   25.16270  21.97076 1.000 79.82331  ? 202  ALA A CB    1 
ATOM   3045 H  H     . ALA A 1 211 ? 4.25644   24.56341  20.55513 1.000 93.99351  ? 202  ALA A H     1 
ATOM   3046 H  HA    . ALA A 1 211 ? 2.18485   26.07034  20.14666 1.000 91.56965  ? 202  ALA A HA    1 
ATOM   3047 H  HB1   . ALA A 1 211 ? 1.62029   25.63370  22.37319 1.000 95.83119  ? 202  ALA A HB1   1 
ATOM   3048 H  HB2   . ALA A 1 211 ? 2.07428   24.29761  21.64363 1.000 95.83119  ? 202  ALA A HB2   1 
ATOM   3049 H  HB3   . ALA A 1 211 ? 3.07543   25.04742  22.62291 1.000 95.83119  ? 202  ALA A HB3   1 
ATOM   3050 N  N     . ALA A 1 212 ? 4.44998   27.48962  21.92743 1.000 79.19435  ? 203  ALA A N     1 
ATOM   3051 C  CA    . ALA A 1 212 ? 4.93115   28.79566  22.36167 1.000 83.05685  ? 203  ALA A CA    1 
ATOM   3052 C  C     . ALA A 1 212 ? 5.08732   29.73763  21.17385 1.000 86.03942  ? 203  ALA A C     1 
ATOM   3053 O  O     . ALA A 1 212 ? 4.49845   30.82267  21.14422 1.000 89.39073  ? 203  ALA A O     1 
ATOM   3054 C  CB    . ALA A 1 212 ? 6.25441   28.64735  23.11282 1.000 75.87494  ? 203  ALA A CB    1 
ATOM   3055 H  H     . ALA A 1 212 ? 4.96040   26.83101  22.14029 1.000 95.07644  ? 203  ALA A H     1 
ATOM   3056 H  HA    . ALA A 1 212 ? 4.28306   29.17975  22.97269 1.000 99.71143  ? 203  ALA A HA    1 
ATOM   3057 H  HB1   . ALA A 1 212 ? 6.55857   29.52479  23.39298 1.000 91.09314  ? 203  ALA A HB1   1 
ATOM   3058 H  HB2   . ALA A 1 212 ? 6.11546   28.08210  23.88875 1.000 91.09314  ? 203  ALA A HB2   1 
ATOM   3059 H  HB3   . ALA A 1 212 ? 6.90924   28.24327  22.52221 1.000 91.09314  ? 203  ALA A HB3   1 
ATOM   3060 N  N     . ALA A 1 213 ? 5.87338   29.32636  20.17207 1.000 83.76553  ? 204  ALA A N     1 
ATOM   3061 C  CA    . ALA A 1 213 ? 6.11440   30.18060  19.01241 1.000 79.98496  ? 204  ALA A CA    1 
ATOM   3062 C  C     . ALA A 1 213 ? 4.80862   30.65629  18.38986 1.000 88.30532  ? 204  ALA A C     1 
ATOM   3063 O  O     . ALA A 1 213 ? 4.66961   31.83465  18.04159 1.000 89.10622  ? 204  ALA A O     1 
ATOM   3064 C  CB    . ALA A 1 213 ? 6.95497   29.43299  17.97573 1.000 75.30259  ? 204  ALA A CB    1 
ATOM   3065 H  H     . ALA A 1 213 ? 6.27312   28.56548  20.14243 1.000 100.56185 ? 204  ALA A H     1 
ATOM   3066 H  HA    . ALA A 1 213 ? 6.61242   30.96135  19.30101 1.000 96.02517  ? 204  ALA A HA    1 
ATOM   3067 H  HB1   . ALA A 1 213 ? 7.10656   30.01381  17.21378 1.000 90.40633  ? 204  ALA A HB1   1 
ATOM   3068 H  HB2   . ALA A 1 213 ? 7.80282   29.18470  18.37623 1.000 90.40633  ? 204  ALA A HB2   1 
ATOM   3069 H  HB3   . ALA A 1 213 ? 6.47611   28.63747  17.69514 1.000 90.40633  ? 204  ALA A HB3   1 
ATOM   3070 N  N     . ARG A 1 214 ? 3.83891   29.75165  18.23700 1.000 84.60935  ? 205  ARG A N     1 
ATOM   3071 C  CA    . ARG A 1 214 ? 2.54449   30.15025  17.69508 1.000 87.86457  ? 205  ARG A CA    1 
ATOM   3072 C  C     . ARG A 1 214 ? 1.87614   31.19075  18.58555 1.000 86.39632  ? 205  ARG A C     1 
ATOM   3073 O  O     . ARG A 1 214 ? 1.30119   32.16671  18.08976 1.000 88.22792  ? 205  ARG A O     1 
ATOM   3074 C  CB    . ARG A 1 214 ? 1.64522   28.92473  17.53142 1.000 80.50651  ? 205  ARG A CB    1 
ATOM   3075 H  H     . ARG A 1 214 ? 3.90536   28.91762  18.43594 1.000 101.57444 ? 205  ARG A H     1 
ATOM   3076 H  HA    . ARG A 1 214 ? 2.67719   30.54325  16.81825 1.000 105.48070 ? 205  ARG A HA    1 
ATOM   3077 N  N     . ARG A 1 215 ? 1.94888   31.00427  19.90581 1.000 85.82755  ? 206  ARG A N     1 
ATOM   3078 C  CA    . ARG A 1 215 ? 1.33022   31.95769  20.82078 1.000 92.15697  ? 206  ARG A CA    1 
ATOM   3079 C  C     . ARG A 1 215 ? 1.99742   33.32486  20.73164 1.000 93.27469  ? 206  ARG A C     1 
ATOM   3080 O  O     . ARG A 1 215 ? 1.32502   34.35813  20.82792 1.000 98.35697  ? 206  ARG A O     1 
ATOM   3081 C  CB    . ARG A 1 215 ? 1.39390   31.42690  22.25303 1.000 83.73778  ? 206  ARG A CB    1 
ATOM   3082 H  H     . ARG A 1 215 ? 2.34457   30.34400  20.28932 1.000 103.03628 ? 206  ARG A H     1 
ATOM   3083 H  HA    . ARG A 1 215 ? 0.39716   32.06129  20.57671 1.000 110.63158 ? 206  ARG A HA    1 
ATOM   3084 N  N     . GLN A 1 216 ? 3.32046   33.35441  20.55084 1.000 88.80228  ? 207  GLN A N     1 
ATOM   3085 C  CA    . GLN A 1 216 ? 4.02055   34.63392  20.48580 1.000 92.19212  ? 207  GLN A CA    1 
ATOM   3086 C  C     . GLN A 1 216 ? 3.73089   35.35206  19.17288 1.000 97.04580  ? 207  GLN A C     1 
ATOM   3087 O  O     . GLN A 1 216 ? 3.57358   36.57839  19.15200 1.000 101.24261 ? 207  GLN A O     1 
ATOM   3088 C  CB    . GLN A 1 216 ? 5.52407   34.42215  20.66724 1.000 93.91387  ? 207  GLN A CB    1 
ATOM   3089 C  CG    . GLN A 1 216 ? 5.87180   33.45921  21.79088 1.000 88.17948  ? 207  GLN A CG    1 
ATOM   3090 C  CD    . GLN A 1 216 ? 7.23531   33.72017  22.40032 1.000 90.79323  ? 207  GLN A CD    1 
ATOM   3091 O  OE1   . GLN A 1 216 ? 8.06753   34.41736  21.82058 1.000 84.96381  ? 207  GLN A OE1   1 
ATOM   3092 N  NE2   . GLN A 1 216 ? 7.46818   33.16118  23.58344 1.000 91.49112  ? 207  GLN A NE2   1 
ATOM   3093 H  H     . GLN A 1 216 ? 3.82353   32.66220  20.46504 1.000 106.60596 ? 207  GLN A H     1 
ATOM   3094 H  HA    . GLN A 1 216 ? 3.71111   35.19806  21.21168 1.000 110.67376 ? 207  GLN A HA    1 
ATOM   3095 H  HB2   . GLN A 1 216 ? 5.89048   34.06263  19.84421 1.000 112.73986 ? 207  GLN A HB2   1 
ATOM   3096 H  HB3   . GLN A 1 216 ? 5.93765   35.27595  20.86941 1.000 112.73986 ? 207  GLN A HB3   1 
ATOM   3097 H  HG2   . GLN A 1 216 ? 5.20953   33.54466  22.49444 1.000 105.85859 ? 207  GLN A HG2   1 
ATOM   3098 H  HG3   . GLN A 1 216 ? 5.86973   32.55434  21.44143 1.000 105.85859 ? 207  GLN A HG3   1 
ATOM   3099 H  HE21  . GLN A 1 216 ? 6.86088   32.68256  23.95989 1.000 109.83256 ? 207  GLN A HE21  1 
ATOM   3100 H  HE22  . GLN A 1 216 ? 8.22615   33.27810  23.97255 1.000 109.83256 ? 207  GLN A HE22  1 
ATOM   3101 N  N     . LEU A 1 217 ? 3.65957   34.60745  18.06645 1.000 95.45731  ? 208  LEU A N     1 
ATOM   3102 C  CA    . LEU A 1 217 ? 3.24058   35.20605  16.80336 1.000 97.18458  ? 208  LEU A CA    1 
ATOM   3103 C  C     . LEU A 1 217 ? 1.83651   35.78527  16.91604 1.000 98.37346  ? 208  LEU A C     1 
ATOM   3104 O  O     . LEU A 1 217 ? 1.56798   36.88721  16.42288 1.000 102.43749 ? 208  LEU A O     1 
ATOM   3105 C  CB    . LEU A 1 217 ? 3.29992   34.16694  15.68422 1.000 97.80345  ? 208  LEU A CB    1 
ATOM   3106 C  CG    . LEU A 1 217 ? 4.51180   34.20738  14.74981 1.000 97.79684  ? 208  LEU A CG    1 
ATOM   3107 C  CD1   . LEU A 1 217 ? 4.46062   35.44236  13.85814 1.000 97.09448  ? 208  LEU A CD1   1 
ATOM   3108 C  CD2   . LEU A 1 217 ? 5.81724   34.16559  15.53004 1.000 92.16357  ? 208  LEU A CD2   1 
ATOM   3109 H  H     . LEU A 1 217 ? 3.84538   33.76889  18.02304 1.000 114.59199 ? 208  LEU A H     1 
ATOM   3110 H  HA    . LEU A 1 217 ? 3.85131   35.92513  16.57792 1.000 116.66471 ? 208  LEU A HA    1 
ATOM   3111 H  HB2   . LEU A 1 217 ? 3.29015   33.28793  16.09428 1.000 117.40735 ? 208  LEU A HB2   1 
ATOM   3112 H  HB3   . LEU A 1 217 ? 2.51286   34.28289  15.12925 1.000 117.40735 ? 208  LEU A HB3   1 
ATOM   3113 H  HG    . LEU A 1 217 ? 4.48604   33.42046  14.18324 1.000 117.39943 ? 208  LEU A HG    1 
ATOM   3114 H  HD11  . LEU A 1 217 ? 5.23788   35.44532  13.27783 1.000 116.55659 ? 208  LEU A HD11  1 
ATOM   3115 H  HD12  . LEU A 1 217 ? 3.65035   35.41403  13.32563 1.000 116.55659 ? 208  LEU A HD12  1 
ATOM   3116 H  HD13  . LEU A 1 217 ? 4.46180   36.23541  14.41667 1.000 116.55659 ? 208  LEU A HD13  1 
ATOM   3117 H  HD21  . LEU A 1 217 ? 6.55903   34.17222  14.90507 1.000 110.63950 ? 208  LEU A HD21  1 
ATOM   3118 H  HD22  . LEU A 1 217 ? 5.86472   34.94312  16.10804 1.000 110.63950 ? 208  LEU A HD22  1 
ATOM   3119 H  HD23  . LEU A 1 217 ? 5.84088   33.35539  16.06289 1.000 110.63950 ? 208  LEU A HD23  1 
ATOM   3120 N  N     . ALA A 1 218 ? 0.92539   35.05388  17.56217 1.000 97.20037  ? 1001 ALA A N     1 
ATOM   3121 C  CA    . ALA A 1 218 ? -0.42655  35.56489  17.75518 1.000 100.44441 ? 1001 ALA A CA    1 
ATOM   3122 C  C     . ALA A 1 218 ? -0.41731  36.81898  18.61868 1.000 102.80305 ? 1001 ALA A C     1 
ATOM   3123 O  O     . ALA A 1 218 ? -1.17348  37.76333  18.36376 1.000 108.63997 ? 1001 ALA A O     1 
ATOM   3124 C  CB    . ALA A 1 218 ? -1.31057  34.48723  18.38250 1.000 93.75093  ? 1001 ALA A CB    1 
ATOM   3125 H  H     . ALA A 1 218 ? 1.06436   34.27198  17.89221 1.000 116.68366 ? 1001 ALA A H     1 
ATOM   3126 H  HA    . ALA A 1 218 ? -0.80292  35.79446  16.89115 1.000 120.57651 ? 1001 ALA A HA    1 
ATOM   3127 H  HB1   . ALA A 1 218 ? -2.21441  34.82932  18.46594 1.000 112.54433 ? 1001 ALA A HB1   1 
ATOM   3128 H  HB2   . ALA A 1 218 ? -1.30515  33.70276  17.81200 1.000 112.54433 ? 1001 ALA A HB2   1 
ATOM   3129 H  HB3   . ALA A 1 218 ? -0.96010  34.26168  19.25840 1.000 112.54433 ? 1001 ALA A HB3   1 
ATOM   3130 N  N     . ASP A 1 219 ? 0.43753   36.84974  19.64385 1.000 100.18900 ? 1002 ASP A N     1 
ATOM   3131 C  CA    . ASP A 1 219 ? 0.52359   38.03178  20.49450 1.000 100.47911 ? 1002 ASP A CA    1 
ATOM   3132 C  C     . ASP A 1 219 ? 1.03052   39.23586  19.71144 1.000 102.02604 ? 1002 ASP A C     1 
ATOM   3133 O  O     . ASP A 1 219 ? 0.52237   40.35153  19.87447 1.000 109.94344 ? 1002 ASP A O     1 
ATOM   3134 C  CB    . ASP A 1 219 ? 1.43014   37.75026  21.69224 1.000 96.68053  ? 1002 ASP A CB    1 
ATOM   3135 C  CG    . ASP A 1 219 ? 0.81629   36.76605  22.66698 1.000 98.07419  ? 1002 ASP A CG    1 
ATOM   3136 O  OD1   . ASP A 1 219 ? -0.26376  36.21762  22.35970 1.000 97.68825  ? 1002 ASP A OD1   1 
ATOM   3137 O  OD2   . ASP A 1 219 ? 1.41085   36.54467  23.74289 1.000 104.95520 ? 1002 ASP A OD2   1 
ATOM   3138 H  H     . ASP A 1 219 ? 0.96859   36.20973  19.86285 1.000 120.27001 ? 1002 ASP A H     1 
ATOM   3139 H  HA    . ASP A 1 219 ? -0.36174  38.24166  20.83072 1.000 120.61815 ? 1002 ASP A HA    1 
ATOM   3140 H  HB2   . ASP A 1 219 ? 2.26743   37.37704  21.37513 1.000 116.05986 ? 1002 ASP A HB2   1 
ATOM   3141 H  HB3   . ASP A 1 219 ? 1.59533   38.58008  22.16659 1.000 116.05986 ? 1002 ASP A HB3   1 
ATOM   3142 N  N     . LEU A 1 220 ? 2.03217   39.03035  18.85427 1.000 104.31155 ? 1003 LEU A N     1 
ATOM   3143 C  CA    . LEU A 1 220 ? 2.55256   40.12871  18.04695 1.000 105.19668 ? 1003 LEU A CA    1 
ATOM   3144 C  C     . LEU A 1 220 ? 1.46900   40.70240  17.14113 1.000 108.46580 ? 1003 LEU A C     1 
ATOM   3145 O  O     . LEU A 1 220 ? 1.23119   41.91576  17.12981 1.000 112.04794 ? 1003 LEU A O     1 
ATOM   3146 C  CB    . LEU A 1 220 ? 3.74819   39.64719  17.22548 1.000 106.28123 ? 1003 LEU A CB    1 
ATOM   3147 C  CG    . LEU A 1 220 ? 5.13951   40.03782  17.73045 1.000 105.69936 ? 1003 LEU A CG    1 
ATOM   3148 C  CD1   . LEU A 1 220 ? 5.30027   39.81424  19.22725 1.000 105.61446 ? 1003 LEU A CD1   1 
ATOM   3149 C  CD2   . LEU A 1 220 ? 6.19409   39.25127  16.96288 1.000 104.56660 ? 1003 LEU A CD2   1 
ATOM   3150 H  H     . LEU A 1 220 ? 2.42144   38.27461  18.72417 1.000 125.21708 ? 1003 LEU A H     1 
ATOM   3151 H  HA    . LEU A 1 220 ? 2.85684   40.83720  18.63547 1.000 126.27923 ? 1003 LEU A HA    1 
ATOM   3152 H  HB2   . LEU A 1 220 ? 3.71950   38.67806  17.19614 1.000 127.58070 ? 1003 LEU A HB2   1 
ATOM   3153 H  HB3   . LEU A 1 220 ? 3.66026   40.00898  16.32978 1.000 127.58070 ? 1003 LEU A HB3   1 
ATOM   3154 H  HG    . LEU A 1 220 ? 5.26344   40.98795  17.57950 1.000 126.88245 ? 1003 LEU A HG    1 
ATOM   3155 H  HD11  . LEU A 1 220 ? 6.20871   40.03714  19.48408 1.000 126.78057 ? 1003 LEU A HD11  1 
ATOM   3156 H  HD12  . LEU A 1 220 ? 4.67357   40.38346  19.70068 1.000 126.78057 ? 1003 LEU A HD12  1 
ATOM   3157 H  HD13  . LEU A 1 220 ? 5.11861   38.88296  19.42876 1.000 126.78057 ? 1003 LEU A HD13  1 
ATOM   3158 H  HD21  . LEU A 1 220 ? 7.07278   39.49522  17.29347 1.000 125.52313 ? 1003 LEU A HD21  1 
ATOM   3159 H  HD22  . LEU A 1 220 ? 6.04134   38.30296  17.09810 1.000 125.52313 ? 1003 LEU A HD22  1 
ATOM   3160 H  HD23  . LEU A 1 220 ? 6.12410   39.46638  16.01962 1.000 125.52313 ? 1003 LEU A HD23  1 
ATOM   3161 N  N     . GLU A 1 221 ? 0.79720   39.84070  16.37184 1.000 110.39951 ? 1004 GLU A N     1 
ATOM   3162 C  CA    . GLU A 1 221 ? -0.27164  40.31595  15.49928 1.000 110.69225 ? 1004 GLU A CA    1 
ATOM   3163 C  C     . GLU A 1 221 ? -1.41049  40.93765  16.29651 1.000 112.52179 ? 1004 GLU A C     1 
ATOM   3164 O  O     . GLU A 1 221 ? -2.05115  41.88442  15.82620 1.000 114.95493 ? 1004 GLU A O     1 
ATOM   3165 C  CB    . GLU A 1 221 ? -0.79604  39.17140  14.63159 1.000 113.10606 ? 1004 GLU A CB    1 
ATOM   3166 C  CG    . GLU A 1 221 ? -0.31209  39.21950  13.18923 1.000 113.15994 ? 1004 GLU A CG    1 
ATOM   3167 C  CD    . GLU A 1 221 ? -0.81667  40.43988  12.43792 1.000 123.55585 ? 1004 GLU A CD    1 
ATOM   3168 O  OE1   . GLU A 1 221 ? 0.00699   41.12944  11.80051 1.000 114.26025 ? 1004 GLU A OE1   1 
ATOM   3169 O  OE2   . GLU A 1 221 ? -2.03722  40.70526  12.47762 1.000 126.15554 ? 1004 GLU A OE2   1 
ATOM   3170 H  H     . GLU A 1 221 ? 0.93953   38.99321  16.33878 1.000 132.52263 ? 1004 GLU A H     1 
ATOM   3171 H  HA    . GLU A 1 221 ? 0.09008   40.99584  14.90953 1.000 132.87392 ? 1004 GLU A HA    1 
ATOM   3172 H  HB2   . GLU A 1 221 ? -0.50119  38.33031  15.01438 1.000 135.77049 ? 1004 GLU A HB2   1 
ATOM   3173 H  HB3   . GLU A 1 221 ? -1.76524  39.20877  14.61956 1.000 135.77049 ? 1004 GLU A HB3   1 
ATOM   3174 H  HG2   . GLU A 1 221 ? 0.65759   39.24318  13.18217 1.000 135.83514 ? 1004 GLU A HG2   1 
ATOM   3175 H  HG3   . GLU A 1 221 ? -0.62805  38.42935  12.72368 1.000 135.83514 ? 1004 GLU A HG3   1 
ATOM   3176 N  N     . ASP A 1 222 ? -1.68100  40.42432  17.49848 1.000 111.55439 ? 1005 ASP A N     1 
ATOM   3177 C  CA    . ASP A 1 222 ? -2.71960  41.02258  18.33005 1.000 111.18911 ? 1005 ASP A CA    1 
ATOM   3178 C  C     . ASP A 1 222 ? -2.33898  42.43672  18.75239 1.000 114.43914 ? 1005 ASP A C     1 
ATOM   3179 O  O     . ASP A 1 222 ? -3.17151  43.34953  18.70264 1.000 115.93353 ? 1005 ASP A O     1 
ATOM   3180 C  CB    . ASP A 1 222 ? -2.98290  40.15066  19.55806 1.000 113.52749 ? 1005 ASP A CB    1 
ATOM   3181 C  CG    . ASP A 1 222 ? -4.22822  39.29410  19.41189 1.000 111.84407 ? 1005 ASP A CG    1 
ATOM   3182 O  OD1   . ASP A 1 222 ? -4.67448  39.07070  18.26690 1.000 117.85097 ? 1005 ASP A OD1   1 
ATOM   3183 O  OD2   . ASP A 1 222 ? -4.76814  38.85198  20.44755 1.000 114.88149 ? 1005 ASP A OD2   1 
ATOM   3184 H  H     . ASP A 1 222 ? -1.28534  39.74478  17.84673 1.000 133.90849 ? 1005 ASP A H     1 
ATOM   3185 H  HA    . ASP A 1 222 ? -3.54062  41.06943  17.81563 1.000 133.47014 ? 1005 ASP A HA    1 
ATOM   3186 H  HB2   . ASP A 1 222 ? -2.22611  39.55941  19.69444 1.000 136.27621 ? 1005 ASP A HB2   1 
ATOM   3187 H  HB3   . ASP A 1 222 ? -3.10099  40.72246  20.33265 1.000 136.27621 ? 1005 ASP A HB3   1 
ATOM   3188 N  N     . ASN A 1 223 ? -1.08501  42.63984  19.16842 1.000 110.40212 ? 1006 ASN A N     1 
ATOM   3189 C  CA    . ASN A 1 223 ? -0.65665  43.97097  19.58703 1.000 112.62984 ? 1006 ASN A CA    1 
ATOM   3190 C  C     . ASN A 1 223 ? -0.65390  44.94743  18.41784 1.000 114.64171 ? 1006 ASN A C     1 
ATOM   3191 O  O     . ASN A 1 223 ? -0.95072  46.13475  18.59864 1.000 114.12703 ? 1006 ASN A O     1 
ATOM   3192 C  CB    . ASN A 1 223 ? 0.72975   43.89611  20.22807 1.000 114.22767 ? 1006 ASN A CB    1 
ATOM   3193 C  CG    . ASN A 1 223 ? 0.68371   43.37924  21.65147 1.000 120.61298 ? 1006 ASN A CG    1 
ATOM   3194 O  OD1   . ASN A 1 223 ? -0.37113  42.98076  22.14521 1.000 117.46329 ? 1006 ASN A OD1   1 
ATOM   3195 N  ND2   . ASN A 1 223 ? 1.83010   43.38242  22.31948 1.000 124.46337 ? 1006 ASN A ND2   1 
ATOM   3196 H  H     . ASN A 1 223 ? -0.47639  42.03410  19.21600 1.000 132.52576 ? 1006 ASN A H     1 
ATOM   3197 H  HA    . ASN A 1 223 ? -1.27461  44.30692  20.25499 1.000 135.19902 ? 1006 ASN A HA    1 
ATOM   3198 H  HB2   . ASN A 1 223 ? 1.28749   43.29658  19.70808 1.000 137.11642 ? 1006 ASN A HB2   1 
ATOM   3199 H  HB3   . ASN A 1 223 ? 1.12058   44.78377  20.24271 1.000 137.11642 ? 1006 ASN A HB3   1 
ATOM   3200 H  HD21  . ASN A 1 223 ? 2.54752   43.66822  21.94102 1.000 149.39927 ? 1006 ASN A HD21  1 
ATOM   3201 H  HD22  . ASN A 1 223 ? 1.85573   43.09868  23.13092 1.000 149.39927 ? 1006 ASN A HD22  1 
ATOM   3202 N  N     . TRP A 1 224 ? -0.32204  44.47244  17.21839 1.000 115.75574 ? 1007 TRP A N     1 
ATOM   3203 C  CA    . TRP A 1 224 ? -0.41298  45.32511  16.03782 1.000 115.34291 ? 1007 TRP A CA    1 
ATOM   3204 C  C     . TRP A 1 224 ? -1.86338  45.67090  15.72417 1.000 117.25060 ? 1007 TRP A C     1 
ATOM   3205 O  O     . TRP A 1 224 ? -2.17704  46.82082  15.39370 1.000 119.36069 ? 1007 TRP A O     1 
ATOM   3206 C  CB    . TRP A 1 224 ? 0.24713   44.63033  14.84634 1.000 112.49189 ? 1007 TRP A CB    1 
ATOM   3207 C  CG    . TRP A 1 224 ? 0.15001   45.37903  13.54052 1.000 115.37666 ? 1007 TRP A CG    1 
ATOM   3208 C  CD1   . TRP A 1 224 ? -0.74701  45.15539  12.53345 1.000 115.41889 ? 1007 TRP A CD1   1 
ATOM   3209 C  CD2   . TRP A 1 224 ? 0.98759   46.45979  13.09671 1.000 111.17924 ? 1007 TRP A CD2   1 
ATOM   3210 N  NE1   . TRP A 1 224 ? -0.52194  46.02771  11.49536 1.000 110.26484 ? 1007 TRP A NE1   1 
ATOM   3211 C  CE2   . TRP A 1 224 ? 0.53531   46.83826  11.81591 1.000 112.27870 ? 1007 TRP A CE2   1 
ATOM   3212 C  CE3   . TRP A 1 224 ? 2.07407   47.14334  13.65779 1.000 109.81416 ? 1007 TRP A CE3   1 
ATOM   3213 C  CZ2   . TRP A 1 224 ? 1.12850   47.86950  11.08884 1.000 114.63682 ? 1007 TRP A CZ2   1 
ATOM   3214 C  CZ3   . TRP A 1 224 ? 2.66220   48.16827  12.93021 1.000 111.77803 ? 1007 TRP A CZ3   1 
ATOM   3215 C  CH2   . TRP A 1 224 ? 2.18738   48.52059  11.66221 1.000 116.02968 ? 1007 TRP A CH2   1 
ATOM   3216 H  H     . TRP A 1 224 ? -0.04571  43.67287  17.06368 1.000 138.95010 ? 1007 TRP A H     1 
ATOM   3217 H  HA    . TRP A 1 224 ? 0.06344   46.15336  16.20494 1.000 138.45471 ? 1007 TRP A HA    1 
ATOM   3218 H  HB2   . TRP A 1 224 ? 1.18924   44.51038  15.04368 1.000 135.03349 ? 1007 TRP A HB2   1 
ATOM   3219 H  HB3   . TRP A 1 224 ? -0.17772  43.76760  14.71947 1.000 135.03349 ? 1007 TRP A HB3   1 
ATOM   3220 H  HD1   . TRP A 1 224 ? -1.41328  44.50673  12.54855 1.000 138.54588 ? 1007 TRP A HD1   1 
ATOM   3221 H  HE1   . TRP A 1 224 ? -0.97188  46.05962  10.76315 1.000 132.36103 ? 1007 TRP A HE1   1 
ATOM   3222 H  HE3   . TRP A 1 224 ? 2.39455   46.91499  14.50043 1.000 131.82021 ? 1007 TRP A HE3   1 
ATOM   3223 H  HZ2   . TRP A 1 224 ? 0.81630   48.10629  10.24542 1.000 137.60740 ? 1007 TRP A HZ2   1 
ATOM   3224 H  HZ3   . TRP A 1 224 ? 3.38461   48.62900  13.29181 1.000 134.17685 ? 1007 TRP A HZ3   1 
ATOM   3225 H  HH2   . TRP A 1 224 ? 2.60047   49.21277  11.19838 1.000 139.27883 ? 1007 TRP A HH2   1 
ATOM   3226 N  N     . GLU A 1 225 ? -2.76298  44.69115  15.83026 1.000 117.77808 ? 1008 GLU A N     1 
ATOM   3227 C  CA    . GLU A 1 225 ? -4.16457  44.93856  15.50900 1.000 120.33215 ? 1008 GLU A CA    1 
ATOM   3228 C  C     . GLU A 1 225 ? -4.80327  45.89941  16.50503 1.000 123.82739 ? 1008 GLU A C     1 
ATOM   3229 O  O     . GLU A 1 225 ? -5.55503  46.79903  16.11123 1.000 126.36408 ? 1008 GLU A O     1 
ATOM   3230 C  CB    . GLU A 1 225 ? -4.93420  43.61854  15.47304 1.000 118.39579 ? 1008 GLU A CB    1 
ATOM   3231 H  H     . GLU A 1 225 ? -2.58912  43.88746  16.08215 1.000 141.37691 ? 1008 GLU A H     1 
ATOM   3232 H  HA    . GLU A 1 225 ? -4.21381  45.34279  14.62862 1.000 144.44179 ? 1008 GLU A HA    1 
ATOM   3233 N  N     . THR A 1 226 ? -4.52765  45.72245  17.79990 1.000 121.93488 ? 1009 THR A N     1 
ATOM   3234 C  CA    . THR A 1 226 ? -5.09798  46.62487  18.79483 1.000 120.37915 ? 1009 THR A CA    1 
ATOM   3235 C  C     . THR A 1 226 ? -4.58214  48.04606  18.60548 1.000 122.10784 ? 1009 THR A C     1 
ATOM   3236 O  O     . THR A 1 226 ? -5.32289  49.01538  18.80738 1.000 124.50613 ? 1009 THR A O     1 
ATOM   3237 C  CB    . THR A 1 226 ? -4.78554  46.13118  20.20843 1.000 114.79930 ? 1009 THR A CB    1 
ATOM   3238 O  OG1   . THR A 1 226 ? -5.36348  47.02632  21.16756 1.000 120.88218 ? 1009 THR A OG1   1 
ATOM   3239 C  CG2   . THR A 1 226 ? -3.28903  46.06094  20.43912 1.000 117.19904 ? 1009 THR A CG2   1 
ATOM   3240 H  H     . THR A 1 226 ? -4.02510  45.10179  18.11899 1.000 146.36507 ? 1009 THR A H     1 
ATOM   3241 H  HA    . THR A 1 226 ? -6.06206  46.63064  18.68793 1.000 144.49820 ? 1009 THR A HA    1 
ATOM   3242 H  HB    . THR A 1 226 ? -5.15448  45.24145  20.32314 1.000 137.80238 ? 1009 THR A HB    1 
ATOM   3243 H  HG1   . THR A 1 226 ? -5.06458  46.85787  21.93429 1.000 145.10183 ? 1009 THR A HG1   1 
ATOM   3244 H  HG21  . THR A 1 226 ? -3.10511  45.66537  21.30549 1.000 140.68206 ? 1009 THR A HG21  1 
ATOM   3245 H  HG22  . THR A 1 226 ? -2.87232  45.51916  19.75084 1.000 140.68206 ? 1009 THR A HG22  1 
ATOM   3246 H  HG23  . THR A 1 226 ? -2.90705  46.95216  20.41251 1.000 140.68206 ? 1009 THR A HG23  1 
ATOM   3247 N  N     . LEU A 1 227 ? -3.31379  48.19158  18.21276 1.000 120.01692 ? 1010 LEU A N     1 
ATOM   3248 C  CA    . LEU A 1 227 ? -2.75256  49.52593  18.03078 1.000 122.75093 ? 1010 LEU A CA    1 
ATOM   3249 C  C     . LEU A 1 227 ? -3.40420  50.24980  16.85959 1.000 124.60712 ? 1010 LEU A C     1 
ATOM   3250 O  O     . LEU A 1 227 ? -3.53319  51.47897  16.88792 1.000 124.42045 ? 1010 LEU A O     1 
ATOM   3251 C  CB    . LEU A 1 227 ? -1.23913  49.43831  17.82697 1.000 117.24113 ? 1010 LEU A CB    1 
ATOM   3252 C  CG    . LEU A 1 227 ? -0.47611  50.76558  17.83637 1.000 121.89252 ? 1010 LEU A CG    1 
ATOM   3253 C  CD1   . LEU A 1 227 ? -0.59513  51.44235  19.18977 1.000 121.40429 ? 1010 LEU A CD1   1 
ATOM   3254 C  CD2   . LEU A 1 227 ? 0.98702   50.56230  17.47885 1.000 121.42331 ? 1010 LEU A CD2   1 
ATOM   3255 H  H     . LEU A 1 227 ? -2.76996  47.54581  18.04895 1.000 144.06352 ? 1010 LEU A H     1 
ATOM   3256 H  HA    . LEU A 1 227 ? -2.91467  50.04540  18.83375 1.000 147.34433 ? 1010 LEU A HA    1 
ATOM   3257 H  HB2   . LEU A 1 227 ? -0.87047  48.89142  18.53823 1.000 140.73257 ? 1010 LEU A HB2   1 
ATOM   3258 H  HB3   . LEU A 1 227 ? -1.07456  49.01987  16.96748 1.000 140.73257 ? 1010 LEU A HB3   1 
ATOM   3259 H  HG    . LEU A 1 227 ? -0.86865  51.34659  17.16611 1.000 146.31424 ? 1010 LEU A HG    1 
ATOM   3260 H  HD11  . LEU A 1 227 ? -0.17132  52.31374  19.14547 1.000 145.72836 ? 1010 LEU A HD11  1 
ATOM   3261 H  HD12  . LEU A 1 227 ? -1.53417  51.54212  19.41146 1.000 145.72836 ? 1010 LEU A HD12  1 
ATOM   3262 H  HD13  . LEU A 1 227 ? -0.15420  50.89361  19.85712 1.000 145.72836 ? 1010 LEU A HD13  1 
ATOM   3263 H  HD21  . LEU A 1 227 ? 1.43164   51.42430  17.46579 1.000 145.75119 ? 1010 LEU A HD21  1 
ATOM   3264 H  HD22  . LEU A 1 227 ? 1.39787   49.98825  18.14411 1.000 145.75119 ? 1010 LEU A HD22  1 
ATOM   3265 H  HD23  . LEU A 1 227 ? 1.04363   50.14762  16.60378 1.000 145.75119 ? 1010 LEU A HD23  1 
ATOM   3266 N  N     . ASN A 1 228 ? -3.82212  49.51205  15.82846 1.000 124.25291 ? 1011 ASN A N     1 
ATOM   3267 C  CA    . ASN A 1 228 ? -4.48728  50.13522  14.68998 1.000 125.11566 ? 1011 ASN A CA    1 
ATOM   3268 C  C     . ASN A 1 228 ? -5.97739  50.32996  14.94589 1.000 129.30525 ? 1011 ASN A C     1 
ATOM   3269 O  O     . ASN A 1 228 ? -6.56013  51.32791  14.50735 1.000 135.18562 ? 1011 ASN A O     1 
ATOM   3270 C  CB    . ASN A 1 228 ? -4.28132  49.28931  13.43314 1.000 124.57806 ? 1011 ASN A CB    1 
ATOM   3271 C  CG    . ASN A 1 228 ? -2.83568  49.24934  12.98534 1.000 120.42215 ? 1011 ASN A CG    1 
ATOM   3272 O  OD1   . ASN A 1 228 ? -1.95704  49.82765  13.62461 1.000 119.03274 ? 1011 ASN A OD1   1 
ATOM   3273 N  ND2   . ASN A 1 228 ? -2.58006  48.55817  11.88078 1.000 119.09454 ? 1011 ASN A ND2   1 
ATOM   3274 H  H     . ASN A 1 228 ? -3.73261  48.65896  15.76651 1.000 149.14670 ? 1011 ASN A H     1 
ATOM   3275 H  HA    . ASN A 1 228 ? -4.08807  51.00655  14.54061 1.000 150.18201 ? 1011 ASN A HA    1 
ATOM   3276 H  HB2   . ASN A 1 228 ? -4.56454  48.37947  13.61444 1.000 149.53688 ? 1011 ASN A HB2   1 
ATOM   3277 H  HB3   . ASN A 1 228 ? -4.80911  49.66326  12.71031 1.000 149.53688 ? 1011 ASN A HB3   1 
ATOM   3278 H  HD21  . ASN A 1 228 ? -3.21985  48.16439  11.46221 1.000 142.95667 ? 1011 ASN A HD21  1 
ATOM   3279 H  HD22  . ASN A 1 228 ? -1.77471  48.50431  11.58394 1.000 142.95667 ? 1011 ASN A HD22  1 
ATOM   3280 N  N     . ASP A 1 229 ? -6.61388  49.38703  15.64257 1.000 125.30729 ? 1012 ASP A N     1 
ATOM   3281 C  CA    . ASP A 1 229 ? -8.04850  49.50341  15.88018 1.000 128.81922 ? 1012 ASP A CA    1 
ATOM   3282 C  C     . ASP A 1 229 ? -8.35720  50.65231  16.83211 1.000 132.43419 ? 1012 ASP A C     1 
ATOM   3283 O  O     . ASP A 1 229 ? -9.29337  51.42481  16.59601 1.000 134.22664 ? 1012 ASP A O     1 
ATOM   3284 C  CB    . ASP A 1 229 ? -8.60054  48.18461  16.41986 1.000 127.79703 ? 1012 ASP A CB    1 
ATOM   3285 C  CG    . ASP A 1 229 ? -8.73982  47.12595  15.33979 1.000 125.95993 ? 1012 ASP A CG    1 
ATOM   3286 O  OD1   . ASP A 1 229 ? -8.39103  47.41105  14.17429 1.000 124.08863 ? 1012 ASP A OD1   1 
ATOM   3287 O  OD2   . ASP A 1 229 ? -9.20215  46.00947  15.65518 1.000 133.02125 ? 1012 ASP A OD2   1 
ATOM   3288 H  H     . ASP A 1 229 ? -6.24569  48.68692  15.98003 1.000 150.41196 ? 1012 ASP A H     1 
ATOM   3289 H  HA    . ASP A 1 229 ? -8.49295  49.68699  15.03777 1.000 154.62628 ? 1012 ASP A HA    1 
ATOM   3290 H  HB2   . ASP A 1 229 ? -7.99839  47.84350  17.09954 1.000 153.39965 ? 1012 ASP A HB2   1 
ATOM   3291 H  HB3   . ASP A 1 229 ? -9.47803  48.34129  16.80243 1.000 153.39965 ? 1012 ASP A HB3   1 
ATOM   3292 N  N     . ASN A 1 230 ? -7.58079  50.78715  17.91080 1.000 130.41770 ? 1013 ASN A N     1 
ATOM   3293 C  CA    . ASN A 1 230 ? -7.77249  51.92192  18.80776 1.000 133.06022 ? 1013 ASN A CA    1 
ATOM   3294 C  C     . ASN A 1 230 ? -7.45848  53.24218  18.11407 1.000 130.61947 ? 1013 ASN A C     1 
ATOM   3295 O  O     . ASN A 1 230 ? -7.97307  54.29028  18.51984 1.000 131.83956 ? 1013 ASN A O     1 
ATOM   3296 C  CB    . ASN A 1 230 ? -6.91420  51.75834  20.06364 1.000 130.22176 ? 1013 ASN A CB    1 
ATOM   3297 C  CG    . ASN A 1 230 ? -7.56411  50.85774  21.09583 1.000 131.02244 ? 1013 ASN A CG    1 
ATOM   3298 O  OD1   . ASN A 1 230 ? -8.78626  50.73058  21.13288 1.000 130.24317 ? 1013 ASN A OD1   1 
ATOM   3299 N  ND2   . ASN A 1 230 ? -6.75190  50.23206  21.94227 1.000 133.82051 ? 1013 ASN A ND2   1 
ATOM   3300 H  H     . ASN A 1 230 ? -6.95140  50.24717  18.13859 1.000 156.54446 ? 1013 ASN A H     1 
ATOM   3301 H  HA    . ASN A 1 230 ? -8.70119  51.94366  19.08695 1.000 159.71547 ? 1013 ASN A HA    1 
ATOM   3302 H  HB2   . ASN A 1 230 ? -6.06169  51.36710  19.81657 1.000 156.30933 ? 1013 ASN A HB2   1 
ATOM   3303 H  HB3   . ASN A 1 230 ? -6.77492  52.62881  20.46834 1.000 156.30933 ? 1013 ASN A HB3   1 
ATOM   3304 H  HD21  . ASN A 1 230 ? -7.07687  49.71117  22.54448 1.000 160.62782 ? 1013 ASN A HD21  1 
ATOM   3305 H  HD22  . ASN A 1 230 ? -5.90153  50.34822  21.88757 1.000 160.62782 ? 1013 ASN A HD22  1 
ATOM   3306 N  N     . LEU A 1 231 ? -6.61300  53.22049  17.07945 1.000 129.17764 ? 1014 LEU A N     1 
ATOM   3307 C  CA    . LEU A 1 231 ? -6.41842  54.41972  16.26933 1.000 128.75433 ? 1014 LEU A CA    1 
ATOM   3308 C  C     . LEU A 1 231 ? -7.72099  54.81670  15.58424 1.000 132.42693 ? 1014 LEU A C     1 
ATOM   3309 O  O     . LEU A 1 231 ? -8.12189  55.98598  15.61038 1.000 134.80703 ? 1014 LEU A O     1 
ATOM   3310 C  CB    . LEU A 1 231 ? -5.31988  54.19528  15.22678 1.000 125.53688 ? 1014 LEU A CB    1 
ATOM   3311 C  CG    . LEU A 1 231 ? -3.85192  54.48238  15.56636 1.000 128.61051 ? 1014 LEU A CG    1 
ATOM   3312 C  CD1   . LEU A 1 231 ? -2.97241  54.24943  14.34783 1.000 126.72878 ? 1014 LEU A CD1   1 
ATOM   3313 C  CD2   . LEU A 1 231 ? -3.65088  55.90421  16.09453 1.000 130.51467 ? 1014 LEU A CD2   1 
ATOM   3314 H  H     . LEU A 1 231 ? -6.15112  52.53833  16.83263 1.000 155.05639 ? 1014 LEU A H     1 
ATOM   3315 H  HA    . LEU A 1 231 ? -6.13227  55.14246  16.84955 1.000 154.54841 ? 1014 LEU A HA    1 
ATOM   3316 H  HB2   . LEU A 1 231 ? -5.35715  53.26027  14.97131 1.000 150.68748 ? 1014 LEU A HB2   1 
ATOM   3317 H  HB3   . LEU A 1 231 ? -5.53249  54.75620  14.46451 1.000 150.68748 ? 1014 LEU A HB3   1 
ATOM   3318 H  HG    . LEU A 1 231 ? -3.58501  53.87285  16.27215 1.000 154.37582 ? 1014 LEU A HG    1 
ATOM   3319 H  HD11  . LEU A 1 231 ? -2.04847  54.42182  14.58764 1.000 152.11775 ? 1014 LEU A HD11  1 
ATOM   3320 H  HD12  . LEU A 1 231 ? -3.07261  53.32941  14.05727 1.000 152.11775 ? 1014 LEU A HD12  1 
ATOM   3321 H  HD13  . LEU A 1 231 ? -3.24823  54.85194  13.63945 1.000 152.11775 ? 1014 LEU A HD13  1 
ATOM   3322 H  HD21  . LEU A 1 231 ? -2.71069  56.03760  16.29240 1.000 156.66082 ? 1014 LEU A HD21  1 
ATOM   3323 H  HD22  . LEU A 1 231 ? -3.93938  56.53627  15.41766 1.000 156.66082 ? 1014 LEU A HD22  1 
ATOM   3324 H  HD23  . LEU A 1 231 ? -4.17809  56.01915  16.90059 1.000 156.66082 ? 1014 LEU A HD23  1 
ATOM   3325 N  N     . LYS A 1 232 ? -8.39371  53.84841  14.95570 1.000 131.24534 ? 1015 LYS A N     1 
ATOM   3326 C  CA    . LYS A 1 232 ? -9.69489  54.12374  14.35577 1.000 130.16598 ? 1015 LYS A CA    1 
ATOM   3327 C  C     . LYS A 1 232 ? -10.68417 54.62193  15.40188 1.000 134.01281 ? 1015 LYS A C     1 
ATOM   3328 O  O     . LYS A 1 232 ? -11.47707 55.53297  15.13519 1.000 135.28980 ? 1015 LYS A O     1 
ATOM   3329 C  CB    . LYS A 1 232 ? -10.23115 52.86749  13.66943 1.000 129.19887 ? 1015 LYS A CB    1 
ATOM   3330 H  H     . LYS A 1 232 ? -8.12139  53.03768  14.86537 1.000 157.53763 ? 1015 LYS A H     1 
ATOM   3331 H  HA    . LYS A 1 232 ? -9.59121  54.81400  13.68221 1.000 156.24239 ? 1015 LYS A HA    1 
ATOM   3332 N  N     . VAL A 1 233 ? -10.65401 54.03202  16.59990 1.000 132.17204 ? 1016 VAL A N     1 
ATOM   3333 C  CA    . VAL A 1 233 ? -11.53351 54.48210  17.67539 1.000 133.04953 ? 1016 VAL A CA    1 
ATOM   3334 C  C     . VAL A 1 233 ? -11.27373 55.94863  17.98884 1.000 136.81905 ? 1016 VAL A C     1 
ATOM   3335 O  O     . VAL A 1 233 ? -12.20991 56.74383  18.14582 1.000 139.07801 ? 1016 VAL A O     1 
ATOM   3336 C  CB    . VAL A 1 233 ? -11.34310 53.59749  18.92353 1.000 132.72802 ? 1016 VAL A CB    1 
ATOM   3337 C  CG1   . VAL A 1 233 ? -12.14296 54.14809  20.09481 1.000 132.33517 ? 1016 VAL A CG1   1 
ATOM   3338 C  CG2   . VAL A 1 233 ? -11.75087 52.15958  18.62830 1.000 132.49929 ? 1016 VAL A CG2   1 
ATOM   3339 H  H     . VAL A 1 233 ? -10.13886 53.37678  16.81177 1.000 158.64966 ? 1016 VAL A H     1 
ATOM   3340 H  HA    . VAL A 1 233 ? -12.45362 54.39446  17.38108 1.000 159.70265 ? 1016 VAL A HA    1 
ATOM   3341 H  HB    . VAL A 1 233 ? -10.40445 53.60179  19.16808 1.000 159.31685 ? 1016 VAL A HB    1 
ATOM   3342 H  HG11  . VAL A 1 233 ? -12.17071 53.48185  20.79926 1.000 158.84542 ? 1016 VAL A HG11  1 
ATOM   3343 H  HG12  . VAL A 1 233 ? -11.71316 54.95486  20.41928 1.000 158.84542 ? 1016 VAL A HG12  1 
ATOM   3344 H  HG13  . VAL A 1 233 ? -13.04308 54.35041  19.79523 1.000 158.84542 ? 1016 VAL A HG13  1 
ATOM   3345 H  HG21  . VAL A 1 233 ? -11.14021 51.55847  19.08289 1.000 159.04236 ? 1016 VAL A HG21  1 
ATOM   3346 H  HG22  . VAL A 1 233 ? -12.65545 52.01593  18.94769 1.000 159.04236 ? 1016 VAL A HG22  1 
ATOM   3347 H  HG23  . VAL A 1 233 ? -11.71054 52.01015  17.67073 1.000 159.04236 ? 1016 VAL A HG23  1 
ATOM   3348 N  N     . ILE A 1 234 ? -9.99895  56.33172  18.07871 1.000 137.25094 ? 1017 ILE A N     1 
ATOM   3349 C  CA    . ILE A 1 234 ? -9.65579  57.71494  18.39239 1.000 138.04950 ? 1017 ILE A CA    1 
ATOM   3350 C  C     . ILE A 1 234 ? -10.12560 58.64446  17.28186 1.000 139.07430 ? 1017 ILE A C     1 
ATOM   3351 O  O     . ILE A 1 234 ? -10.55817 59.77486  17.53812 1.000 140.55033 ? 1017 ILE A O     1 
ATOM   3352 C  CB    . ILE A 1 234 ? -8.14035  57.84534  18.63285 1.000 132.48362 ? 1017 ILE A CB    1 
ATOM   3353 H  H     . ILE A 1 234 ? -9.32166  55.81442  17.96344 1.000 164.74434 ? 1017 ILE A H     1 
ATOM   3354 H  HA    . ILE A 1 234 ? -10.11415 57.96852  19.20878 1.000 165.70262 ? 1017 ILE A HA    1 
ATOM   3355 N  N     . GLU A 1 235 ? -10.04579 58.18725  16.03163 1.000 138.75041 ? 1018 GLU A N     1 
ATOM   3356 C  CA    . GLU A 1 235 ? -10.51325 58.99740  14.91246 1.000 138.26233 ? 1018 GLU A CA    1 
ATOM   3357 C  C     . GLU A 1 235 ? -11.99489 59.32264  15.05911 1.000 140.39107 ? 1018 GLU A C     1 
ATOM   3358 O  O     . GLU A 1 235 ? -12.38481 60.49211  15.15392 1.000 142.79260 ? 1018 GLU A O     1 
ATOM   3359 C  CB    . GLU A 1 235 ? -10.24781 58.26560  13.59303 1.000 138.17412 ? 1018 GLU A CB    1 
ATOM   3360 C  CG    . GLU A 1 235 ? -10.72992 59.00546  12.34532 1.000 141.50899 ? 1018 GLU A CG    1 
ATOM   3361 C  CD    . GLU A 1 235 ? -12.22836 58.87919  12.11520 1.000 142.54806 ? 1018 GLU A CD    1 
ATOM   3362 O  OE1   . GLU A 1 235 ? -12.78037 57.78384  12.35231 1.000 143.58143 ? 1018 GLU A OE1   1 
ATOM   3363 O  OE2   . GLU A 1 235 ? -12.85573 59.88094  11.71025 1.000 146.65435 ? 1018 GLU A OE2   1 
ATOM   3364 H  H     . GLU A 1 235 ? -9.72838  57.41969  15.80869 1.000 166.54371 ? 1018 GLU A H     1 
ATOM   3365 H  HA    . GLU A 1 235 ? -10.01907 59.83199  14.90020 1.000 165.95801 ? 1018 GLU A HA    1 
ATOM   3366 H  HB2   . GLU A 1 235 ? -9.29148  58.13127  13.50196 1.000 165.85216 ? 1018 GLU A HB2   1 
ATOM   3367 H  HB3   . GLU A 1 235 ? -10.70219 57.40899  13.61877 1.000 165.85216 ? 1018 GLU A HB3   1 
ATOM   3368 H  HG2   . GLU A 1 235 ? -10.52107 59.94812  12.43843 1.000 169.85401 ? 1018 GLU A HG2   1 
ATOM   3369 H  HG3   . GLU A 1 235 ? -10.27735 58.64049  11.56887 1.000 169.85401 ? 1018 GLU A HG3   1 
ATOM   3370 N  N     . LYS A 1 236 ? -12.83786 58.29100  15.08077 1.000 140.82658 ? 1019 LYS A N     1 
ATOM   3371 C  CA    . LYS A 1 236 ? -14.28387 58.46543  15.03999 1.000 141.14343 ? 1019 LYS A CA    1 
ATOM   3372 C  C     . LYS A 1 236 ? -14.88627 58.86827  16.37986 1.000 139.74744 ? 1019 LYS A C     1 
ATOM   3373 O  O     . LYS A 1 236 ? -16.11226 58.99530  16.47071 1.000 142.16910 ? 1019 LYS A O     1 
ATOM   3374 C  CB    . LYS A 1 236 ? -14.94782 57.17245  14.55525 1.000 138.88068 ? 1019 LYS A CB    1 
ATOM   3375 H  H     . LYS A 1 236 ? -12.59062 57.46821  15.11953 1.000 169.03511 ? 1019 LYS A H     1 
ATOM   3376 H  HA    . LYS A 1 236 ? -14.48520 59.17205  14.40670 1.000 169.41533 ? 1019 LYS A HA    1 
ATOM   3377 N  N     . ALA A 1 237 ? -14.07345 59.07431  17.41237 1.000 141.48511 ? 1020 ALA A N     1 
ATOM   3378 C  CA    . ALA A 1 237 ? -14.61165 59.44343  18.71251 1.000 144.46676 ? 1020 ALA A CA    1 
ATOM   3379 C  C     . ALA A 1 237 ? -15.29465 60.80675  18.63961 1.000 147.14323 ? 1020 ALA A C     1 
ATOM   3380 O  O     . ALA A 1 237 ? -15.10101 61.58353  17.69998 1.000 145.24700 ? 1020 ALA A O     1 
ATOM   3381 C  CB    . ALA A 1 237 ? -13.50511 59.46140  19.76628 1.000 144.90021 ? 1020 ALA A CB    1 
ATOM   3382 H  H     . ALA A 1 237 ? -13.21653 59.00707  17.38469 1.000 169.82535 ? 1020 ALA A H     1 
ATOM   3383 H  HA    . ALA A 1 237 ? -15.27260 58.78846  18.98647 1.000 173.40333 ? 1020 ALA A HA    1 
ATOM   3384 H  HB1   . ALA A 1 237 ? -13.88684 59.71651  20.62074 1.000 173.92347 ? 1020 ALA A HB1   1 
ATOM   3385 H  HB2   . ALA A 1 237 ? -13.11487 58.57562  19.82957 1.000 173.92347 ? 1020 ALA A HB2   1 
ATOM   3386 H  HB3   . ALA A 1 237 ? -12.82759 60.10323  19.50184 1.000 173.92347 ? 1020 ALA A HB3   1 
ATOM   3387 N  N     . ASP A 1 238 ? -16.10898 61.09069  19.65648 1.000 145.56983 ? 1021 ASP A N     1 
ATOM   3388 C  CA    . ASP A 1 238 ? -16.87463 62.32946  19.71714 1.000 148.10646 ? 1021 ASP A CA    1 
ATOM   3389 C  C     . ASP A 1 238 ? -16.68452 63.12024  21.00224 1.000 145.87970 ? 1021 ASP A C     1 
ATOM   3390 O  O     . ASP A 1 238 ? -16.99666 64.31731  21.01043 1.000 142.82612 ? 1021 ASP A O     1 
ATOM   3391 C  CB    . ASP A 1 238 ? -18.37335 62.03911  19.53875 1.000 151.08506 ? 1021 ASP A CB    1 
ATOM   3392 C  CG    . ASP A 1 238 ? -18.79950 60.74649  20.20619 1.000 146.55193 ? 1021 ASP A CG    1 
ATOM   3393 O  OD1   . ASP A 1 238 ? -17.92792 60.05360  20.77166 1.000 148.97993 ? 1021 ASP A OD1   1 
ATOM   3394 O  OD2   . ASP A 1 238 ? -20.00473 60.42231  20.16365 1.000 151.25460 ? 1021 ASP A OD2   1 
ATOM   3395 H  H     . ASP A 1 238 ? -16.23500 60.57288  20.33145 1.000 174.72701 ? 1021 ASP A H     1 
ATOM   3396 H  HA    . ASP A 1 238 ? -16.59262 62.89812  18.98366 1.000 177.77097 ? 1021 ASP A HA    1 
ATOM   3397 H  HB2   . ASP A 1 238 ? -18.88525 62.76333  19.93165 1.000 181.34528 ? 1021 ASP A HB2   1 
ATOM   3398 H  HB3   . ASP A 1 238 ? -18.57174 61.96821  18.59191 1.000 181.34528 ? 1021 ASP A HB3   1 
ATOM   3399 N  N     . ASN A 1 239 ? -16.19076 62.51021  22.07756 1.000 144.60477 ? 1022 ASN A N     1 
ATOM   3400 C  CA    . ASN A 1 239 ? -15.95180 63.20741  23.33186 1.000 145.81011 ? 1022 ASN A CA    1 
ATOM   3401 C  C     . ASN A 1 239 ? -14.57649 62.83332  23.86739 1.000 141.17794 ? 1022 ASN A C     1 
ATOM   3402 O  O     . ASN A 1 239 ? -13.96491 61.85046  23.44100 1.000 140.75646 ? 1022 ASN A O     1 
ATOM   3403 C  CB    . ASN A 1 239 ? -17.03179 62.88087  24.37244 1.000 146.09762 ? 1022 ASN A CB    1 
ATOM   3404 C  CG    . ASN A 1 239 ? -17.06618 61.41061  24.73474 1.000 143.19551 ? 1022 ASN A CG    1 
ATOM   3405 O  OD1   . ASN A 1 239 ? -16.51723 60.99906  25.75579 1.000 144.00863 ? 1022 ASN A OD1   1 
ATOM   3406 N  ND2   . ASN A 1 239 ? -17.71059 60.60871  23.89529 1.000 139.46338 ? 1022 ASN A ND2   1 
ATOM   3407 H  H     . ASN A 1 239 ? -15.98315 61.67601  22.10249 1.000 173.56893 ? 1022 ASN A H     1 
ATOM   3408 H  HA    . ASN A 1 239 ? -15.96360 64.16480  23.17638 1.000 175.01535 ? 1022 ASN A HA    1 
ATOM   3409 H  HB2   . ASN A 1 239 ? -16.85478 63.38569  25.18158 1.000 175.36036 ? 1022 ASN A HB2   1 
ATOM   3410 H  HB3   . ASN A 1 239 ? -17.90016 63.12242  24.01399 1.000 175.36036 ? 1022 ASN A HB3   1 
ATOM   3411 H  HD21  . ASN A 1 239 ? -17.75804 59.76541  24.05714 1.000 167.39927 ? 1022 ASN A HD21  1 
ATOM   3412 H  HD22  . ASN A 1 239 ? -18.08054 60.93261  23.18972 1.000 167.39927 ? 1022 ASN A HD22  1 
ATOM   3413 N  N     . ALA A 1 240 ? -14.09434 63.63971  24.81685 1.000 140.82552 ? 1023 ALA A N     1 
ATOM   3414 C  CA    . ALA A 1 240 ? -12.74985 63.43770  25.34570 1.000 143.22426 ? 1023 ALA A CA    1 
ATOM   3415 C  C     . ALA A 1 240 ? -12.62155 62.10995  26.07873 1.000 144.32019 ? 1023 ALA A C     1 
ATOM   3416 O  O     . ALA A 1 240 ? -11.56038 61.47706  26.03262 1.000 143.55328 ? 1023 ALA A O     1 
ATOM   3417 C  CB    . ALA A 1 240 ? -12.37476 64.58731  26.28188 1.000 137.47634 ? 1023 ALA A CB    1 
ATOM   3418 H  H     . ALA A 1 240 ? -14.52061 64.30048  25.16509 1.000 169.03384 ? 1023 ALA A H     1 
ATOM   3419 H  HA    . ALA A 1 240 ? -12.12694 63.43245  24.60215 1.000 171.91232 ? 1023 ALA A HA    1 
ATOM   3420 H  HB1   . ALA A 1 240 ? -11.47729 64.43994  26.61914 1.000 165.01483 ? 1023 ALA A HB1   1 
ATOM   3421 H  HB2   . ALA A 1 240 ? -12.40961 65.42124  25.78768 1.000 165.01483 ? 1023 ALA A HB2   1 
ATOM   3422 H  HB3   . ALA A 1 240 ? -13.00499 64.61292  27.01880 1.000 165.01483 ? 1023 ALA A HB3   1 
ATOM   3423 N  N     . ALA A 1 241 ? -13.68155 61.67290  26.76201 1.000 146.20385 ? 1024 ALA A N     1 
ATOM   3424 C  CA    . ALA A 1 241 ? -13.59113 60.44931  27.55182 1.000 144.95153 ? 1024 ALA A CA    1 
ATOM   3425 C  C     . ALA A 1 241 ? -13.37237 59.23099  26.66351 1.000 140.84959 ? 1024 ALA A C     1 
ATOM   3426 O  O     . ALA A 1 241 ? -12.61708 58.32089  27.02445 1.000 143.51692 ? 1024 ALA A O     1 
ATOM   3427 C  CB    . ALA A 1 241 ? -14.85187 60.27593  28.39817 1.000 144.24026 ? 1024 ALA A CB    1 
ATOM   3428 H  H     . ALA A 1 241 ? -14.44921 62.05998  26.78359 1.000 175.48784 ? 1024 ALA A H     1 
ATOM   3429 H  HA    . ALA A 1 241 ? -12.83317 60.52278  28.15265 1.000 173.98505 ? 1024 ALA A HA    1 
ATOM   3430 H  HB1   . ALA A 1 241 ? -14.75150 59.48933  28.95681 1.000 173.13153 ? 1024 ALA A HB1   1 
ATOM   3431 H  HB2   . ALA A 1 241 ? -14.97046 61.06272  28.95297 1.000 173.13153 ? 1024 ALA A HB2   1 
ATOM   3432 H  HB3   . ALA A 1 241 ? -15.61517 60.16827  27.80937 1.000 173.13153 ? 1024 ALA A HB3   1 
ATOM   3433 N  N     . GLN A 1 242 ? -14.02258 59.19371  25.49914 1.000 141.52022 ? 1025 GLN A N     1 
ATOM   3434 C  CA    . GLN A 1 242 ? -13.84838 58.06339  24.59303 1.000 140.49853 ? 1025 GLN A CA    1 
ATOM   3435 C  C     . GLN A 1 242 ? -12.42841 58.02449  24.04126 1.000 140.78974 ? 1025 GLN A C     1 
ATOM   3436 O  O     . GLN A 1 242 ? -11.79924 56.96098  23.98882 1.000 137.44204 ? 1025 GLN A O     1 
ATOM   3437 C  CB    . GLN A 1 242 ? -14.86585 58.14573  23.45689 1.000 140.52499 ? 1025 GLN A CB    1 
ATOM   3438 C  CG    . GLN A 1 242 ? -15.01751 56.86010  22.66596 1.000 138.30170 ? 1025 GLN A CG    1 
ATOM   3439 C  CD    . GLN A 1 242 ? -15.61474 57.09605  21.29467 1.000 142.35985 ? 1025 GLN A CD    1 
ATOM   3440 O  OE1   . GLN A 1 242 ? -16.07290 58.19585  20.98917 1.000 146.94276 ? 1025 GLN A OE1   1 
ATOM   3441 N  NE2   . GLN A 1 242 ? -15.60594 56.06499  20.45726 1.000 147.30038 ? 1025 GLN A NE2   1 
ATOM   3442 H  H     . GLN A 1 242 ? -14.56149 59.80116  25.21597 1.000 169.86748 ? 1025 GLN A H     1 
ATOM   3443 H  HA    . GLN A 1 242 ? -14.00711 57.23970  25.08012 1.000 168.64145 ? 1025 GLN A HA    1 
ATOM   3444 H  HB2   . GLN A 1 242 ? -15.73309 58.36474  23.83218 1.000 168.67320 ? 1025 GLN A HB2   1 
ATOM   3445 H  HB3   . GLN A 1 242 ? -14.58649 58.84002  22.83979 1.000 168.67320 ? 1025 GLN A HB3   1 
ATOM   3446 H  HG2   . GLN A 1 242 ? -14.14443 56.45394  22.54913 1.000 166.00525 ? 1025 GLN A HG2   1 
ATOM   3447 H  HG3   . GLN A 1 242 ? -15.60225 56.25623  23.15002 1.000 166.00525 ? 1025 GLN A HG3   1 
ATOM   3448 H  HE21  . GLN A 1 242 ? -15.27217 55.31227  20.70547 1.000 176.80367 ? 1025 GLN A HE21  1 
ATOM   3449 H  HE22  . GLN A 1 242 ? -15.93401 56.15016  19.66687 1.000 176.80367 ? 1025 GLN A HE22  1 
ATOM   3450 N  N     . VAL A 1 243 ? -11.91128 59.17870  23.61284 1.000 141.67245 ? 1026 VAL A N     1 
ATOM   3451 C  CA    . VAL A 1 243 ? -10.51429 59.25706  23.19744 1.000 140.46293 ? 1026 VAL A CA    1 
ATOM   3452 C  C     . VAL A 1 243 ? -9.60804  58.76089  24.31539 1.000 138.66374 ? 1026 VAL A C     1 
ATOM   3453 O  O     . VAL A 1 243 ? -8.65577  58.00854  24.07695 1.000 139.57391 ? 1026 VAL A O     1 
ATOM   3454 C  CB    . VAL A 1 243 ? -10.16271 60.69716  22.77780 1.000 144.32695 ? 1026 VAL A CB    1 
ATOM   3455 C  CG1   . VAL A 1 243 ? -8.66068  60.84864  22.57542 1.000 137.13508 ? 1026 VAL A CG1   1 
ATOM   3456 C  CG2   . VAL A 1 243 ? -10.91655 61.07637  21.51066 1.000 142.22848 ? 1026 VAL A CG2   1 
ATOM   3457 H  H     . VAL A 1 243 ? -12.34367 59.91981  23.55460 1.000 170.05016 ? 1026 VAL A H     1 
ATOM   3458 H  HA    . VAL A 1 243 ? -10.38459 58.68264  22.42665 1.000 168.59873 ? 1026 VAL A HA    1 
ATOM   3459 H  HB    . VAL A 1 243 ? -10.43027 61.30413  23.48554 1.000 173.23555 ? 1026 VAL A HB    1 
ATOM   3460 H  HG11  . VAL A 1 243 ? -8.49177  61.64538  22.04856 1.000 164.60531 ? 1026 VAL A HG11  1 
ATOM   3461 H  HG12  . VAL A 1 243 ? -8.23169  60.92789  23.44178 1.000 164.60531 ? 1026 VAL A HG12  1 
ATOM   3462 H  HG13  . VAL A 1 243 ? -8.32430  60.06688  22.11002 1.000 164.60531 ? 1026 VAL A HG13  1 
ATOM   3463 H  HG21  . VAL A 1 243 ? -10.65925 61.97360  21.24669 1.000 170.71739 ? 1026 VAL A HG21  1 
ATOM   3464 H  HG22  . VAL A 1 243 ? -10.68997 60.44709  20.80812 1.000 170.71739 ? 1026 VAL A HG22  1 
ATOM   3465 H  HG23  . VAL A 1 243 ? -11.86955 61.04442  21.68863 1.000 170.71739 ? 1026 VAL A HG23  1 
ATOM   3466 N  N     . LYS A 1 244 ? -9.89924  59.15994  25.55545 1.000 140.74947 ? 1027 LYS A N     1 
ATOM   3467 C  CA    . LYS A 1 244 ? -9.10091  58.69713  26.68514 1.000 139.81236 ? 1027 LYS A CA    1 
ATOM   3468 C  C     . LYS A 1 244 ? -9.15943  57.18002  26.81517 1.000 139.03418 ? 1027 LYS A C     1 
ATOM   3469 O  O     . LYS A 1 244 ? -8.14993  56.53653  27.12494 1.000 140.17642 ? 1027 LYS A O     1 
ATOM   3470 C  CB    . LYS A 1 244 ? -9.58145  59.36430  27.97367 1.000 138.05294 ? 1027 LYS A CB    1 
ATOM   3471 H  H     . LYS A 1 244 ? -10.54365 59.68972  25.76440 1.000 168.94258 ? 1027 LYS A H     1 
ATOM   3472 H  HA    . LYS A 1 244 ? -8.17614  58.95186  26.54086 1.000 167.81805 ? 1027 LYS A HA    1 
ATOM   3473 N  N     . ASP A 1 245 ? -10.33412 56.58990  26.58517 1.000 139.44060 ? 1028 ASP A N     1 
ATOM   3474 C  CA    . ASP A 1 245 ? -10.45665 55.13615  26.64115 1.000 137.26759 ? 1028 ASP A CA    1 
ATOM   3475 C  C     . ASP A 1 245 ? -9.48870  54.46846  25.67144 1.000 134.65976 ? 1028 ASP A C     1 
ATOM   3476 O  O     . ASP A 1 245 ? -8.69670  53.60247  26.06186 1.000 136.56639 ? 1028 ASP A O     1 
ATOM   3477 C  CB    . ASP A 1 245 ? -11.90066 54.72691  26.33961 1.000 136.12205 ? 1028 ASP A CB    1 
ATOM   3478 C  CG    . ASP A 1 245 ? -12.04545 53.24126  26.05693 1.000 134.86614 ? 1028 ASP A CG    1 
ATOM   3479 O  OD1   . ASP A 1 245 ? -11.56203 52.77835  25.00171 1.000 133.69302 ? 1028 ASP A OD1   1 
ATOM   3480 O  OD2   . ASP A 1 245 ? -12.64199 52.53364  26.89485 1.000 143.56928 ? 1028 ASP A OD2   1 
ATOM   3481 H  H     . ASP A 1 245 ? -11.06429 57.00365  26.39737 1.000 167.37193 ? 1028 ASP A H     1 
ATOM   3482 H  HA    . ASP A 1 245 ? -10.23809 54.83316  27.53631 1.000 164.76432 ? 1028 ASP A HA    1 
ATOM   3483 H  HB2   . ASP A 1 245 ? -12.45624 54.94180  27.10516 1.000 163.38967 ? 1028 ASP A HB2   1 
ATOM   3484 H  HB3   . ASP A 1 245 ? -12.20990 55.21205  25.55865 1.000 163.38967 ? 1028 ASP A HB3   1 
ATOM   3485 N  N     . ALA A 1 246 ? -9.53778  54.86272  24.39711 1.000 133.62577 ? 1029 ALA A N     1 
ATOM   3486 C  CA    . ALA A 1 246 ? -8.68284  54.23642  23.39453 1.000 134.76926 ? 1029 ALA A CA    1 
ATOM   3487 C  C     . ALA A 1 246 ? -7.20732  54.44300  23.71098 1.000 134.74640 ? 1029 ALA A C     1 
ATOM   3488 O  O     . ALA A 1 246 ? -6.39262  53.53059  23.53018 1.000 135.22290 ? 1029 ALA A O     1 
ATOM   3489 C  CB    . ALA A 1 246 ? -9.00750  54.79324  22.00878 1.000 136.64068 ? 1029 ALA A CB    1 
ATOM   3490 H  H     . ALA A 1 246 ? -10.05084 55.48226  24.09291 1.000 160.39414 ? 1029 ALA A H     1 
ATOM   3491 H  HA    . ALA A 1 246 ? -8.85980  53.28271  23.39163 1.000 161.76633 ? 1029 ALA A HA    1 
ATOM   3492 H  HB1   . ALA A 1 246 ? -8.47427  54.32506  21.34744 1.000 164.01203 ? 1029 ALA A HB1   1 
ATOM   3493 H  HB2   . ALA A 1 246 ? -9.95104  54.65953  21.82782 1.000 164.01203 ? 1029 ALA A HB2   1 
ATOM   3494 H  HB3   . ALA A 1 246 ? -8.79844  55.74030  21.99205 1.000 164.01203 ? 1029 ALA A HB3   1 
ATOM   3495 N  N     . LEU A 1 247 ? -6.84143  55.63685  24.18112 1.000 137.00437 ? 1030 LEU A N     1 
ATOM   3496 C  CA    . LEU A 1 247 ? -5.43083  55.93279  24.40599 1.000 136.36647 ? 1030 LEU A CA    1 
ATOM   3497 C  C     . LEU A 1 247 ? -4.88683  55.17517  25.61233 1.000 136.38763 ? 1030 LEU A C     1 
ATOM   3498 O  O     . LEU A 1 247 ? -3.74506  54.70163  25.58810 1.000 136.36987 ? 1030 LEU A O     1 
ATOM   3499 C  CB    . LEU A 1 247 ? -5.22992  57.43678  24.58369 1.000 135.02159 ? 1030 LEU A CB    1 
ATOM   3500 C  CG    . LEU A 1 247 ? -5.56170  58.34699  23.39743 1.000 137.59157 ? 1030 LEU A CG    1 
ATOM   3501 C  CD1   . LEU A 1 247 ? -5.08613  59.76251  23.70018 1.000 132.12934 ? 1030 LEU A CD1   1 
ATOM   3502 C  CD2   . LEU A 1 247 ? -4.96240  57.84865  22.09100 1.000 134.65639 ? 1030 LEU A CD2   1 
ATOM   3503 H  H     . LEU A 1 247 ? -7.38037  56.27881  24.37355 1.000 164.44846 ? 1030 LEU A H     1 
ATOM   3504 H  HA    . LEU A 1 247 ? -4.92874  55.65207  23.62497 1.000 163.68298 ? 1030 LEU A HA    1 
ATOM   3505 H  HB2   . LEU A 1 247 ? -5.78996  57.72433  25.32164 1.000 162.06913 ? 1030 LEU A HB2   1 
ATOM   3506 H  HB3   . LEU A 1 247 ? -4.29586  57.58660  24.79809 1.000 162.06913 ? 1030 LEU A HB3   1 
ATOM   3507 H  HG    . LEU A 1 247 ? -6.52332  58.34585  23.27023 1.000 165.15310 ? 1030 LEU A HG    1 
ATOM   3508 H  HD11  . LEU A 1 247 ? -5.32647  60.34150  22.95997 1.000 158.59843 ? 1030 LEU A HD11  1 
ATOM   3509 H  HD12  . LEU A 1 247 ? -5.51328  60.07182  24.51429 1.000 158.59843 ? 1030 LEU A HD12  1 
ATOM   3510 H  HD13  . LEU A 1 247 ? -4.12293  59.75438  23.81453 1.000 158.59843 ? 1030 LEU A HD13  1 
ATOM   3511 H  HD21  . LEU A 1 247 ? -5.16396  58.48567  21.38781 1.000 161.63089 ? 1030 LEU A HD21  1 
ATOM   3512 H  HD22  . LEU A 1 247 ? -4.00175  57.76477  22.19594 1.000 161.63089 ? 1030 LEU A HD22  1 
ATOM   3513 H  HD23  . LEU A 1 247 ? -5.34827  56.98515  21.87564 1.000 161.63089 ? 1030 LEU A HD23  1 
ATOM   3514 N  N     . THR A 1 248 ? -5.67886  55.05652  26.68079 1.000 134.86223 ? 1031 THR A N     1 
ATOM   3515 C  CA    . THR A 1 248 ? -5.23608  54.27956  27.83497 1.000 140.83889 ? 1031 THR A CA    1 
ATOM   3516 C  C     . THR A 1 248 ? -4.96141  52.83404  27.43698 1.000 138.78759 ? 1031 THR A C     1 
ATOM   3517 O  O     . THR A 1 248 ? -3.93407  52.25683  27.81149 1.000 143.57968 ? 1031 THR A O     1 
ATOM   3518 C  CB    . THR A 1 248 ? -6.27864  54.34393  28.95319 1.000 136.30179 ? 1031 THR A CB    1 
ATOM   3519 O  OG1   . THR A 1 248 ? -7.59525  54.25459  28.39480 1.000 136.16334 ? 1031 THR A OG1   1 
ATOM   3520 C  CG2   . THR A 1 248 ? -6.14419  55.63969  29.74192 1.000 138.66068 ? 1031 THR A CG2   1 
ATOM   3521 H  H     . THR A 1 248 ? -6.45947  55.40877  26.75935 1.000 161.87789 ? 1031 THR A H     1 
ATOM   3522 H  HA    . THR A 1 248 ? -4.41448  54.66618  28.17614 1.000 169.04989 ? 1031 THR A HA    1 
ATOM   3523 H  HB    . THR A 1 248 ? -6.14008  53.60319  29.56393 1.000 163.60536 ? 1031 THR A HB    1 
ATOM   3524 H  HG1   . THR A 1 248 ? -8.17072  54.34404  29.00013 1.000 163.43922 ? 1031 THR A HG1   1 
ATOM   3525 H  HG21  . THR A 1 248 ? -6.80329  55.66507  30.45315 1.000 166.43603 ? 1031 THR A HG21  1 
ATOM   3526 H  HG22  . THR A 1 248 ? -5.25800  55.70042  30.13165 1.000 166.43603 ? 1031 THR A HG22  1 
ATOM   3527 H  HG23  . THR A 1 248 ? -6.28341  56.40043  29.15643 1.000 166.43603 ? 1031 THR A HG23  1 
ATOM   3528 N  N     . LYS A 1 249 ? -5.87448  52.23234  26.67113 1.000 143.17785 ? 1032 LYS A N     1 
ATOM   3529 C  CA    . LYS A 1 249 ? -5.61841  50.90184  26.12956 1.000 138.38671 ? 1032 LYS A CA    1 
ATOM   3530 C  C     . LYS A 1 249 ? -4.33949  50.88905  25.30142 1.000 137.37289 ? 1032 LYS A C     1 
ATOM   3531 O  O     . LYS A 1 249 ? -3.53011  49.95953  25.40613 1.000 141.23656 ? 1032 LYS A O     1 
ATOM   3532 C  CB    . LYS A 1 249 ? -6.80783  50.44274  25.28673 1.000 135.13122 ? 1032 LYS A CB    1 
ATOM   3533 H  H     . LYS A 1 249 ? -6.63609  52.56822  26.45497 1.000 171.85664 ? 1032 LYS A H     1 
ATOM   3534 H  HA    . LYS A 1 249 ? -5.51177  50.27631  26.86321 1.000 166.10727 ? 1032 LYS A HA    1 
ATOM   3535 N  N     . MET A 1 250 ? -4.13811  51.91521  24.47409 1.000 141.58058 ? 1033 MET A N     1 
ATOM   3536 C  CA    . MET A 1 250 ? -2.91604  51.99816  23.68293 1.000 138.03788 ? 1033 MET A CA    1 
ATOM   3537 C  C     . MET A 1 250 ? -1.68282  51.98686  24.57459 1.000 138.37660 ? 1033 MET A C     1 
ATOM   3538 O  O     . MET A 1 250 ? -0.76851  51.17611  24.38402 1.000 140.69363 ? 1033 MET A O     1 
ATOM   3539 C  CB    . MET A 1 250 ? -2.92698  53.26677  22.83543 1.000 136.36212 ? 1033 MET A CB    1 
ATOM   3540 C  CG    . MET A 1 250 ? -3.92254  53.26176  21.70590 1.000 137.67636 ? 1033 MET A CG    1 
ATOM   3541 S  SD    . MET A 1 250 ? -3.06326  53.69449  20.19449 1.000 136.87808 ? 1033 MET A SD    1 
ATOM   3542 C  CE    . MET A 1 250 ? -4.38114  53.59994  19.00388 1.000 131.74386 ? 1033 MET A CE    1 
ATOM   3543 H  H     . MET A 1 250 ? -4.68674  52.56671  24.35517 1.000 169.93992 ? 1033 MET A H     1 
ATOM   3544 H  HA    . MET A 1 250 ? -2.88924  51.23184  23.08884 1.000 165.68868 ? 1033 MET A HA    1 
ATOM   3545 H  HB2   . MET A 1 250 ? -3.14072  54.01882  23.40957 1.000 163.67776 ? 1033 MET A HB2   1 
ATOM   3546 H  HB3   . MET A 1 250 ? -2.04592  53.38549  22.44743 1.000 163.67776 ? 1033 MET A HB3   1 
ATOM   3547 H  HG2   . MET A 1 250 ? -4.31167  52.37851  21.60917 1.000 165.25484 ? 1033 MET A HG2   1 
ATOM   3548 H  HG3   . MET A 1 250 ? -4.61976  53.91487  21.87389 1.000 165.25484 ? 1033 MET A HG3   1 
ATOM   3549 H  HE1   . MET A 1 250 ? -4.02881  53.81179  18.12531 1.000 158.13585 ? 1033 MET A HE1   1 
ATOM   3550 H  HE2   . MET A 1 250 ? -4.74504  52.70079  19.00634 1.000 158.13585 ? 1033 MET A HE2   1 
ATOM   3551 H  HE3   . MET A 1 250 ? -5.07157  54.23687  19.24578 1.000 158.13585 ? 1033 MET A HE3   1 
ATOM   3552 N  N     . ARG A 1 251 ? -1.63632  52.89681  25.55002 1.000 137.56586 ? 1034 ARG A N     1 
ATOM   3553 C  CA    . ARG A 1 251 ? -0.43419  53.04964  26.36002 1.000 138.07685 ? 1034 ARG A CA    1 
ATOM   3554 C  C     . ARG A 1 251 ? -0.05128  51.73709  27.02761 1.000 142.87166 ? 1034 ARG A C     1 
ATOM   3555 O  O     . ARG A 1 251 ? 1.12927   51.37040  27.06363 1.000 146.04022 ? 1034 ARG A O     1 
ATOM   3556 C  CB    . ARG A 1 251 ? -0.64399  54.14058  27.40768 1.000 133.51018 ? 1034 ARG A CB    1 
ATOM   3557 C  CG    . ARG A 1 251 ? 0.64067   54.83939  27.79479 1.000 129.65930 ? 1034 ARG A CG    1 
ATOM   3558 C  CD    . ARG A 1 251 ? 0.43848   55.82000  28.93063 1.000 131.24126 ? 1034 ARG A CD    1 
ATOM   3559 N  NE    . ARG A 1 251 ? 1.71605   56.21423  29.51109 1.000 127.35154 ? 1034 ARG A NE    1 
ATOM   3560 C  CZ    . ARG A 1 251 ? 2.36942   55.51297  30.42791 1.000 138.16212 ? 1034 ARG A CZ    1 
ATOM   3561 N  NH1   . ARG A 1 251 ? 1.87977   54.38385  30.91443 1.000 132.92573 ? 1034 ARG A NH1   1 
ATOM   3562 N  NH2   . ARG A 1 251 ? 3.54544   55.95372  30.86496 1.000 133.27888 ? 1034 ARG A NH2   1 
ATOM   3563 H  H     . ARG A 1 251 ? -2.27885  53.42915  25.75830 1.000 165.12225 ? 1034 ARG A H     1 
ATOM   3564 H  HA    . ARG A 1 251 ? 0.29829   53.32104  25.78495 1.000 165.73544 ? 1034 ARG A HA    1 
ATOM   3565 H  HB2   . ARG A 1 251 ? -1.25218  54.80694  27.05134 1.000 160.25543 ? 1034 ARG A HB2   1 
ATOM   3566 H  HB3   . ARG A 1 251 ? -1.02086  53.74131  28.20734 1.000 160.25543 ? 1034 ARG A HB3   1 
ATOM   3567 H  HG2   . ARG A 1 251 ? 1.29019   54.17753  28.07935 1.000 155.63437 ? 1034 ARG A HG2   1 
ATOM   3568 H  HG3   . ARG A 1 251 ? 0.97990   55.32952  27.02955 1.000 155.63437 ? 1034 ARG A HG3   1 
ATOM   3569 H  HD2   . ARG A 1 251 ? -0.00581  56.61485  28.59636 1.000 157.53273 ? 1034 ARG A HD2   1 
ATOM   3570 H  HD3   . ARG A 1 251 ? -0.09941  55.40585  29.62348 1.000 157.53273 ? 1034 ARG A HD3   1 
ATOM   3571 H  HE    . ARG A 1 251 ? 2.06961   56.95029  29.24124 1.000 152.86506 ? 1034 ARG A HE    1 
ATOM   3572 H  HH11  . ARG A 1 251 ? 1.12117   54.08909  30.63652 1.000 159.55409 ? 1034 ARG A HH11  1 
ATOM   3573 H  HH12  . ARG A 1 251 ? 2.32018   53.94486  31.50851 1.000 159.55409 ? 1034 ARG A HH12  1 
ATOM   3574 H  HH21  . ARG A 1 251 ? 3.87335   56.68513  30.55332 1.000 159.97787 ? 1034 ARG A HH21  1 
ATOM   3575 H  HH22  . ARG A 1 251 ? 3.97809   55.50735  31.45924 1.000 159.97787 ? 1034 ARG A HH22  1 
ATOM   3576 N  N     . ALA A 1 252 ? -1.03680  51.01538  27.56303 1.000 143.26126 ? 1035 ALA A N     1 
ATOM   3577 C  CA    . ALA A 1 252 ? -0.76017  49.71356  28.15888 1.000 143.15463 ? 1035 ALA A CA    1 
ATOM   3578 C  C     . ALA A 1 252 ? -0.19573  48.75164  27.12127 1.000 143.65793 ? 1035 ALA A C     1 
ATOM   3579 O  O     . ALA A 1 252 ? 0.78580   48.04514  27.37877 1.000 143.94287 ? 1035 ALA A O     1 
ATOM   3580 C  CB    . ALA A 1 252 ? -2.03361  49.14661  28.78581 1.000 141.43695 ? 1035 ALA A CB    1 
ATOM   3581 H  H     . ALA A 1 252 ? -1.86224  51.25490  27.59287 1.000 171.95672 ? 1035 ALA A H     1 
ATOM   3582 H  HA    . ALA A 1 252 ? -0.10105  49.82093  28.86240 1.000 171.82877 ? 1035 ALA A HA    1 
ATOM   3583 H  HB1   . ALA A 1 252 ? -1.83679  48.27791  29.16990 1.000 169.76755 ? 1035 ALA A HB1   1 
ATOM   3584 H  HB2   . ALA A 1 252 ? -2.34148  49.75230  29.47810 1.000 169.76755 ? 1035 ALA A HB2   1 
ATOM   3585 H  HB3   . ALA A 1 252 ? -2.71188  49.05820  28.09805 1.000 169.76755 ? 1035 ALA A HB3   1 
ATOM   3586 N  N     . ALA A 1 253 ? -0.80705  48.71251  25.93489 1.000 140.28389 ? 1036 ALA A N     1 
ATOM   3587 C  CA    . ALA A 1 253 ? -0.30627  47.84514  24.87498 1.000 140.03150 ? 1036 ALA A CA    1 
ATOM   3588 C  C     . ALA A 1 253 ? 1.09894   48.24170  24.44160 1.000 141.78881 ? 1036 ALA A C     1 
ATOM   3589 O  O     . ALA A 1 253 ? 1.87760   47.38640  24.00451 1.000 140.21334 ? 1036 ALA A O     1 
ATOM   3590 C  CB    . ALA A 1 253 ? -1.25689  47.88016  23.67809 1.000 148.98068 ? 1036 ALA A CB    1 
ATOM   3591 H  H     . ALA A 1 253 ? -1.50261  49.17197  25.72351 1.000 168.38388 ? 1036 ALA A H     1 
ATOM   3592 H  HA    . ALA A 1 253 ? -0.27190  46.93478  25.20810 1.000 168.08102 ? 1036 ALA A HA    1 
ATOM   3593 H  HB1   . ALA A 1 253 ? -0.91912  47.28681  22.98907 1.000 178.82003 ? 1036 ALA A HB1   1 
ATOM   3594 H  HB2   . ALA A 1 253 ? -2.13625  47.58767  23.96456 1.000 178.82003 ? 1036 ALA A HB2   1 
ATOM   3595 H  HB3   . ALA A 1 253 ? -1.30436  48.78770  23.33895 1.000 178.82003 ? 1036 ALA A HB3   1 
ATOM   3596 N  N     . ALA A 1 254 ? 1.44249   49.52687  24.55262 1.000 142.85427 ? 1037 ALA A N     1 
ATOM   3597 C  CA    . ALA A 1 254 ? 2.76442   49.97874  24.13050 1.000 138.74655 ? 1037 ALA A CA    1 
ATOM   3598 C  C     . ALA A 1 254 ? 3.84013   49.50522  25.10052 1.000 147.74654 ? 1037 ALA A C     1 
ATOM   3599 O  O     . ALA A 1 254 ? 4.82950   48.88632  24.69180 1.000 144.17573 ? 1037 ALA A O     1 
ATOM   3600 C  CB    . ALA A 1 254 ? 2.78167   51.50236  24.00412 1.000 134.52488 ? 1037 ALA A CB    1 
ATOM   3601 H  H     . ALA A 1 254 ? 0.93483   50.14693  24.86473 1.000 171.46833 ? 1037 ALA A H     1 
ATOM   3602 H  HA    . ALA A 1 254 ? 2.96030   49.60349  23.25773 1.000 166.53907 ? 1037 ALA A HA    1 
ATOM   3603 H  HB1   . ALA A 1 254 ? 3.66369   51.78541  23.71635 1.000 161.47307 ? 1037 ALA A HB1   1 
ATOM   3604 H  HB2   . ALA A 1 254 ? 2.11791   51.77256  23.35042 1.000 161.47307 ? 1037 ALA A HB2   1 
ATOM   3605 H  HB3   . ALA A 1 254 ? 2.57408   51.89321  24.86728 1.000 161.47307 ? 1037 ALA A HB3   1 
ATOM   3606 N  N     . LEU A 1 255 ? 3.66614   49.78949  26.39400 1.000 146.61091 ? 1038 LEU A N     1 
ATOM   3607 C  CA    . LEU A 1 255 ? 4.60624   49.29190  27.39139 1.000 147.74497 ? 1038 LEU A CA    1 
ATOM   3608 C  C     . LEU A 1 255 ? 4.61778   47.77006  27.45091 1.000 150.81639 ? 1038 LEU A C     1 
ATOM   3609 O  O     . LEU A 1 255 ? 5.58284   47.18581  27.95581 1.000 152.84630 ? 1038 LEU A O     1 
ATOM   3610 C  CB    . LEU A 1 255 ? 4.26682   49.86141  28.77049 1.000 144.68692 ? 1038 LEU A CB    1 
ATOM   3611 C  CG    . LEU A 1 255 ? 4.33168   51.38308  28.92055 1.000 147.07843 ? 1038 LEU A CG    1 
ATOM   3612 C  CD1   . LEU A 1 255 ? 3.91298   51.80345  30.32423 1.000 150.87562 ? 1038 LEU A CD1   1 
ATOM   3613 C  CD2   . LEU A 1 255 ? 5.72414   51.90591  28.60580 1.000 146.44464 ? 1038 LEU A CD2   1 
ATOM   3614 H  H     . LEU A 1 255 ? 3.02124   50.26117  26.71217 1.000 175.97631 ? 1038 LEU A H     1 
ATOM   3615 H  HA    . LEU A 1 255 ? 5.49747   49.59418  27.15637 1.000 177.33718 ? 1038 LEU A HA    1 
ATOM   3616 H  HB2   . LEU A 1 255 ? 3.36143   49.59234  28.99132 1.000 173.66752 ? 1038 LEU A HB2   1 
ATOM   3617 H  HB3   . LEU A 1 255 ? 4.89029   49.48573  29.41162 1.000 173.66752 ? 1038 LEU A HB3   1 
ATOM   3618 H  HG    . LEU A 1 255 ? 3.71446   51.77987  28.28612 1.000 176.53733 ? 1038 LEU A HG    1 
ATOM   3619 H  HD11  . LEU A 1 255 ? 3.87186   52.77173  30.36483 1.000 181.09396 ? 1038 LEU A HD11  1 
ATOM   3620 H  HD12  . LEU A 1 255 ? 3.04070   51.42685  30.51968 1.000 181.09396 ? 1038 LEU A HD12  1 
ATOM   3621 H  HD13  . LEU A 1 255 ? 4.56608   51.47313  30.96082 1.000 181.09396 ? 1038 LEU A HD13  1 
ATOM   3622 H  HD21  . LEU A 1 255 ? 5.73488   52.86830  28.72655 1.000 175.77678 ? 1038 LEU A HD21  1 
ATOM   3623 H  HD22  . LEU A 1 255 ? 6.36114   51.48991  29.20753 1.000 175.77678 ? 1038 LEU A HD22  1 
ATOM   3624 H  HD23  . LEU A 1 255 ? 5.94413   51.68531  27.68719 1.000 175.77678 ? 1038 LEU A HD23  1 
ATOM   3625 N  N     . ASP A 1 256 ? 3.56591   47.11862  26.95177 1.000 149.97874 ? 1039 ASP A N     1 
ATOM   3626 C  CA    . ASP A 1 256 ? 3.52743   45.66132  26.91368 1.000 150.62980 ? 1039 ASP A CA    1 
ATOM   3627 C  C     . ASP A 1 256 ? 4.38308   45.11688  25.77574 1.000 149.00872 ? 1039 ASP A C     1 
ATOM   3628 O  O     . ASP A 1 256 ? 5.25073   44.26418  25.99394 1.000 150.39461 ? 1039 ASP A O     1 
ATOM   3629 C  CB    . ASP A 1 256 ? 2.08022   45.18664  26.77021 1.000 144.79095 ? 1039 ASP A CB    1 
ATOM   3630 C  CG    . ASP A 1 256 ? 1.97998   43.72246  26.39430 1.000 140.84104 ? 1039 ASP A CG    1 
ATOM   3631 O  OD1   . ASP A 1 256 ? 1.78046   42.88601  27.29995 1.000 147.63506 ? 1039 ASP A OD1   1 
ATOM   3632 O  OD2   . ASP A 1 256 ? 2.10565   43.40832  25.19146 1.000 143.05858 ? 1039 ASP A OD2   1 
ATOM   3633 H  H     . ASP A 1 256 ? 2.86435   47.49804  26.63013 1.000 180.01770 ? 1039 ASP A H     1 
ATOM   3634 H  HA    . ASP A 1 256 ? 3.88006   45.31312  27.74753 1.000 180.79897 ? 1039 ASP A HA    1 
ATOM   3635 H  HB2   . ASP A 1 256 ? 1.62099   45.31173  27.61541 1.000 173.79236 ? 1039 ASP A HB2   1 
ATOM   3636 H  HB3   . ASP A 1 256 ? 1.64450   45.70535  26.07595 1.000 173.79236 ? 1039 ASP A HB3   1 
ATOM   3637 N  N     . ALA A 1 257 ? 4.15231   45.60189  24.55265 1.000 146.64962 ? 1040 ALA A N     1 
ATOM   3638 C  CA    . ALA A 1 257 ? 4.92181   45.12173  23.41087 1.000 150.67927 ? 1040 ALA A CA    1 
ATOM   3639 C  C     . ALA A 1 257 ? 6.40129   45.44378  23.55882 1.000 152.96504 ? 1040 ALA A C     1 
ATOM   3640 O  O     . ALA A 1 257 ? 7.25173   44.70988  23.04197 1.000 153.15834 ? 1040 ALA A O     1 
ATOM   3641 C  CB    . ALA A 1 257 ? 4.37980   45.73081  22.11820 1.000 144.36836 ? 1040 ALA A CB    1 
ATOM   3642 H  H     . ALA A 1 257 ? 3.56442   46.20012  24.36262 1.000 176.02276 ? 1040 ALA A H     1 
ATOM   3643 H  HA    . ALA A 1 257 ? 4.82527   44.15816  23.35506 1.000 180.85834 ? 1040 ALA A HA    1 
ATOM   3644 H  HB1   . ALA A 1 257 ? 4.83715   45.32829  21.36341 1.000 173.28525 ? 1040 ALA A HB1   1 
ATOM   3645 H  HB2   . ALA A 1 257 ? 3.42778   45.55402  22.06072 1.000 173.28525 ? 1040 ALA A HB2   1 
ATOM   3646 H  HB3   . ALA A 1 257 ? 4.53848   46.68768  22.12916 1.000 173.28525 ? 1040 ALA A HB3   1 
ATOM   3647 N  N     . GLN A 1 258 ? 6.72658   46.53269  24.25958 1.000 153.89471 ? 1041 GLN A N     1 
ATOM   3648 C  CA    . GLN A 1 258 ? 8.12401   46.90467  24.44378 1.000 151.40388 ? 1041 GLN A CA    1 
ATOM   3649 C  C     . GLN A 1 258 ? 8.92484   45.77883  25.08433 1.000 160.79714 ? 1041 GLN A C     1 
ATOM   3650 O  O     . GLN A 1 258 ? 10.13249  45.66781  24.84927 1.000 167.92648 ? 1041 GLN A O     1 
ATOM   3651 C  CB    . GLN A 1 258 ? 8.22005   48.16878  25.29994 1.000 150.50351 ? 1041 GLN A CB    1 
ATOM   3652 H  H     . GLN A 1 258 ? 6.16298   47.06438  24.63274 1.000 184.71686 ? 1041 GLN A H     1 
ATOM   3653 H  HA    . GLN A 1 258 ? 8.51182   47.09470  23.57523 1.000 181.72787 ? 1041 GLN A HA    1 
ATOM   3654 N  N     . LYS A 1 259 ? 8.27950   44.93156  25.88566 1.000 162.27722 ? 1042 LYS A N     1 
ATOM   3655 C  CA    . LYS A 1 259 ? 9.01445   43.91489  26.63609 1.000 166.78591 ? 1042 LYS A CA    1 
ATOM   3656 C  C     . LYS A 1 259 ? 9.43446   42.73357  25.76745 1.000 171.66374 ? 1042 LYS A C     1 
ATOM   3657 O  O     . LYS A 1 259 ? 10.60955  42.34714  25.75668 1.000 172.81198 ? 1042 LYS A O     1 
ATOM   3658 C  CB    . LYS A 1 259 ? 8.16373   43.40717  27.79742 1.000 164.17281 ? 1042 LYS A CB    1 
ATOM   3659 H  H     . LYS A 1 259 ? 7.42869   44.92423  26.01081 1.000 194.77587 ? 1042 LYS A H     1 
ATOM   3660 H  HA    . LYS A 1 259 ? 9.81817   44.33312  26.98252 1.000 200.18631 ? 1042 LYS A HA    1 
ATOM   3661 N  N     . ALA A 1 260 ? 8.47198   42.11027  25.09181 1.000 195.54068 ? 1043 ALA A N     1 
ATOM   3662 C  CA    . ALA A 1 260 ? 8.71649   40.95476  24.23432 1.000 182.71068 ? 1043 ALA A CA    1 
ATOM   3663 C  C     . ALA A 1 260 ? 9.24203   41.38427  22.86865 1.000 171.61686 ? 1043 ALA A C     1 
ATOM   3664 O  O     . ALA A 1 260 ? 8.71283   40.97810  21.83311 1.000 169.84792 ? 1043 ALA A O     1 
ATOM   3665 C  CB    . ALA A 1 260 ? 7.43895   40.13469  24.07484 1.000 221.50068 ? 1043 ALA A CB    1 
ATOM   3666 N  N     . HIS A 1 280 ? 14.55871  52.39674  20.79803 1.000 118.86402 ? 1063 HIS A N     1 
ATOM   3667 C  CA    . HIS A 1 280 ? 14.27829  53.73353  21.30834 1.000 119.04256 ? 1063 HIS A CA    1 
ATOM   3668 C  C     . HIS A 1 280 ? 13.09813  54.37333  20.57983 1.000 116.96468 ? 1063 HIS A C     1 
ATOM   3669 O  O     . HIS A 1 280 ? 12.70151  55.49445  20.89529 1.000 117.37714 ? 1063 HIS A O     1 
ATOM   3670 C  CB    . HIS A 1 280 ? 15.51626  54.62399  21.17827 1.000 119.14498 ? 1063 HIS A CB    1 
ATOM   3671 H  H     . HIS A 1 280 ? 15.18569  52.37122  20.20995 1.000 142.68004 ? 1063 HIS A H     1 
ATOM   3672 H  HA    . HIS A 1 280 ? 14.04620  53.66603  22.24774 1.000 142.89429 ? 1063 HIS A HA    1 
ATOM   3673 N  N     . GLY A 1 281 ? 12.54357  53.65910  19.59849 1.000 115.93326 ? 1064 GLY A N     1 
ATOM   3674 C  CA    . GLY A 1 281 ? 11.36862  54.16468  18.90723 1.000 114.60683 ? 1064 GLY A CA    1 
ATOM   3675 C  C     . GLY A 1 281 ? 10.12504  54.12585  19.77396 1.000 116.56564 ? 1064 GLY A C     1 
ATOM   3676 O  O     . GLY A 1 281 ? 9.26199   55.00385  19.67823 1.000 114.37696 ? 1064 GLY A O     1 
ATOM   3677 H  H     . GLY A 1 281 ? 12.82507  52.89495  19.32203 1.000 139.16313 ? 1064 GLY A H     1 
ATOM   3678 H  HA2   . GLY A 1 281 ? 11.52517  55.08352  18.63867 1.000 137.57141 ? 1064 GLY A HA2   1 
ATOM   3679 H  HA3   . GLY A 1 281 ? 11.20628  53.62768  18.11591 1.000 137.57141 ? 1064 GLY A HA3   1 
ATOM   3680 N  N     . PHE A 1 282 ? 10.01177  53.10412  20.62712 1.000 119.90818 ? 1065 PHE A N     1 
ATOM   3681 C  CA    . PHE A 1 282 ? 8.88105   53.02918  21.54550 1.000 119.83416 ? 1065 PHE A CA    1 
ATOM   3682 C  C     . PHE A 1 282 ? 8.79570   54.27590  22.41401 1.000 117.04819 ? 1065 PHE A C     1 
ATOM   3683 O  O     . PHE A 1 282 ? 7.70450   54.81711  22.62075 1.000 115.48744 ? 1065 PHE A O     1 
ATOM   3684 C  CB    . PHE A 1 282 ? 8.99225   51.77647  22.41336 1.000 124.28388 ? 1065 PHE A CB    1 
ATOM   3685 C  CG    . PHE A 1 282 ? 8.35553   50.55980  21.80445 1.000 134.88248 ? 1065 PHE A CG    1 
ATOM   3686 C  CD1   . PHE A 1 282 ? 8.94910   49.90947  20.73426 1.000 127.58439 ? 1065 PHE A CD1   1 
ATOM   3687 C  CD2   . PHE A 1 282 ? 7.16876   50.05787  22.31166 1.000 151.17411 ? 1065 PHE A CD2   1 
ATOM   3688 C  CE1   . PHE A 1 282 ? 8.36397   48.78587  20.17489 1.000 135.05414 ? 1065 PHE A CE1   1 
ATOM   3689 C  CE2   . PHE A 1 282 ? 6.58016   48.93583  21.75798 1.000 158.01959 ? 1065 PHE A CE2   1 
ATOM   3690 C  CZ    . PHE A 1 282 ? 7.17892   48.29851  20.68933 1.000 147.82536 ? 1065 PHE A CZ    1 
ATOM   3691 H  H     . PHE A 1 282 ? 10.56899  52.45223  20.69151 1.000 143.93303 ? 1065 PHE A H     1 
ATOM   3692 H  HA    . PHE A 1 282 ? 8.06209   52.96473  21.02971 1.000 143.84421 ? 1065 PHE A HA    1 
ATOM   3693 H  HB2   . PHE A 1 282 ? 9.93100   51.57884  22.55691 1.000 149.18388 ? 1065 PHE A HB2   1 
ATOM   3694 H  HB3   . PHE A 1 282 ? 8.55520   51.94564  23.26264 1.000 149.18388 ? 1065 PHE A HB3   1 
ATOM   3695 H  HD1   . PHE A 1 282 ? 9.74980   50.23142  20.38766 1.000 153.14448 ? 1065 PHE A HD1   1 
ATOM   3696 H  HD2   . PHE A 1 282 ? 6.76261   50.48066  23.03360 1.000 181.45215 ? 1065 PHE A HD2   1 
ATOM   3697 H  HE1   . PHE A 1 282 ? 8.76860   48.36019  19.45381 1.000 162.10818 ? 1065 PHE A HE1   1 
ATOM   3698 H  HE2   . PHE A 1 282 ? 5.78115   48.61046  22.10528 1.000 189.66673 ? 1065 PHE A HE2   1 
ATOM   3699 H  HZ    . PHE A 1 282 ? 6.78495   47.54283  20.31697 1.000 177.43365 ? 1065 PHE A HZ    1 
ATOM   3700 N  N     . ASP A 1 283 ? 9.93771   54.74534  22.92904 1.000 115.17648 ? 1066 ASP A N     1 
ATOM   3701 C  CA    . ASP A 1 283 ? 9.97664   55.99315  23.68560 1.000 116.35042 ? 1066 ASP A CA    1 
ATOM   3702 C  C     . ASP A 1 283 ? 9.13365   57.07428  23.02246 1.000 112.66062 ? 1066 ASP A C     1 
ATOM   3703 O  O     . ASP A 1 283 ? 8.32639   57.74254  23.67716 1.000 113.94545 ? 1066 ASP A O     1 
ATOM   3704 C  CB    . ASP A 1 283 ? 11.42383  56.47550  23.82807 1.000 117.41984 ? 1066 ASP A CB    1 
ATOM   3705 C  CG    . ASP A 1 283 ? 12.22724  55.64108  24.80465 1.000 120.97869 ? 1066 ASP A CG    1 
ATOM   3706 O  OD1   . ASP A 1 283 ? 11.63051  55.09203  25.75444 1.000 121.12370 ? 1066 ASP A OD1   1 
ATOM   3707 O  OD2   . ASP A 1 283 ? 13.45971  55.54116  24.62644 1.000 123.99168 ? 1066 ASP A OD2   1 
ATOM   3708 H  H     . ASP A 1 283 ? 10.70170  54.35791  22.85276 1.000 138.25500 ? 1066 ASP A H     1 
ATOM   3709 H  HA    . ASP A 1 283 ? 9.62067   55.82411  24.57195 1.000 139.66373 ? 1066 ASP A HA    1 
ATOM   3710 H  HB2   . ASP A 1 283 ? 11.85970  56.42687  22.96288 1.000 140.94702 ? 1066 ASP A HB2   1 
ATOM   3711 H  HB3   . ASP A 1 283 ? 11.42161  57.39142  24.14742 1.000 140.94702 ? 1066 ASP A HB3   1 
ATOM   3712 N  N     . ILE A 1 284 ? 9.31713   57.26465  21.71496 1.000 113.77336 ? 1067 ILE A N     1 
ATOM   3713 C  CA    . ILE A 1 284 ? 8.50221   58.23585  20.99233 1.000 109.14627 ? 1067 ILE A CA    1 
ATOM   3714 C  C     . ILE A 1 284 ? 7.02970   57.85743  21.09648 1.000 112.76171 ? 1067 ILE A C     1 
ATOM   3715 O  O     . ILE A 1 284 ? 6.18015   58.68667  21.44048 1.000 108.52150 ? 1067 ILE A O     1 
ATOM   3716 C  CB    . ILE A 1 284 ? 8.95912   58.33971  19.52596 1.000 110.20994 ? 1067 ILE A CB    1 
ATOM   3717 C  CG1   . ILE A 1 284 ? 10.36245  58.94873  19.42853 1.000 103.64706 ? 1067 ILE A CG1   1 
ATOM   3718 C  CG2   . ILE A 1 284 ? 7.99265   59.19809  18.71731 1.000 110.73516 ? 1067 ILE A CG2   1 
ATOM   3719 C  CD1   . ILE A 1 284 ? 11.49790  57.95871  19.57554 1.000 109.49717 ? 1067 ILE A CD1   1 
ATOM   3720 H  H     . ILE A 1 284 ? 9.89680   56.85097  21.23283 1.000 136.57125 ? 1067 ILE A H     1 
ATOM   3721 H  HA    . ILE A 1 284 ? 8.62063   59.10790  21.40027 1.000 131.01874 ? 1067 ILE A HA    1 
ATOM   3722 H  HB    . ILE A 1 284 ? 8.97447   57.43859  19.16730 1.000 132.29514 ? 1067 ILE A HB    1 
ATOM   3723 H  HG12  . ILE A 1 284 ? 10.45482  59.37099  18.56016 1.000 124.41968 ? 1067 ILE A HG12  1 
ATOM   3724 H  HG13  . ILE A 1 284 ? 10.46005  59.61027  20.13119 1.000 124.41968 ? 1067 ILE A HG13  1 
ATOM   3725 H  HG21  . ILE A 1 284 ? 8.34201   59.30600  17.81886 1.000 132.92541 ? 1067 ILE A HG21  1 
ATOM   3726 H  HG22  . ILE A 1 284 ? 7.12923   58.75717  18.68573 1.000 132.92541 ? 1067 ILE A HG22  1 
ATOM   3727 H  HG23  . ILE A 1 284 ? 7.90618   60.06448  19.14486 1.000 132.92541 ? 1067 ILE A HG23  1 
ATOM   3728 H  HD11  . ILE A 1 284 ? 12.33291  58.40102  19.35640 1.000 131.43982 ? 1067 ILE A HD11  1 
ATOM   3729 H  HD12  . ILE A 1 284 ? 11.52268  57.64031  20.49146 1.000 131.43982 ? 1067 ILE A HD12  1 
ATOM   3730 H  HD13  . ILE A 1 284 ? 11.34883  57.21511  18.97077 1.000 131.43982 ? 1067 ILE A HD13  1 
ATOM   3731 N  N     . LEU A 1 285 ? 6.71020   56.59089  20.82273 1.000 115.42409 ? 1068 LEU A N     1 
ATOM   3732 C  CA    . LEU A 1 285 ? 5.32728   56.12728  20.83275 1.000 111.73167 ? 1068 LEU A CA    1 
ATOM   3733 C  C     . LEU A 1 285 ? 4.65016   56.43858  22.16284 1.000 110.24046 ? 1068 LEU A C     1 
ATOM   3734 O  O     . LEU A 1 285 ? 3.70563   57.23312  22.20681 1.000 111.74753 ? 1068 LEU A O     1 
ATOM   3735 C  CB    . LEU A 1 285 ? 5.26117   54.62357  20.54690 1.000 115.17206 ? 1068 LEU A CB    1 
ATOM   3736 C  CG    . LEU A 1 285 ? 3.87296   54.08678  20.18305 1.000 114.95073 ? 1068 LEU A CG    1 
ATOM   3737 C  CD1   . LEU A 1 285 ? 3.41896   54.62562  18.83226 1.000 119.66601 ? 1068 LEU A CD1   1 
ATOM   3738 C  CD2   . LEU A 1 285 ? 3.84915   52.56504  20.18246 1.000 118.12547 ? 1068 LEU A CD2   1 
ATOM   3739 H  H     . LEU A 1 285 ? 7.28168   55.97869  20.62720 1.000 138.55213 ? 1068 LEU A H     1 
ATOM   3740 H  HA    . LEU A 1 285 ? 4.84154   56.59226  20.13365 1.000 134.12122 ? 1068 LEU A HA    1 
ATOM   3741 H  HB2   . LEU A 1 285 ? 5.85208   54.42811  19.80292 1.000 138.24968 ? 1068 LEU A HB2   1 
ATOM   3742 H  HB3   . LEU A 1 285 ? 5.55731   54.14899  21.33935 1.000 138.24968 ? 1068 LEU A HB3   1 
ATOM   3743 H  HG    . LEU A 1 285 ? 3.24593   54.39142  20.85753 1.000 137.98409 ? 1068 LEU A HG    1 
ATOM   3744 H  HD11  . LEU A 1 285 ? 2.54222   54.26498  18.62689 1.000 143.64243 ? 1068 LEU A HD11  1 
ATOM   3745 H  HD12  . LEU A 1 285 ? 3.37634   55.59367  18.87657 1.000 143.64243 ? 1068 LEU A HD12  1 
ATOM   3746 H  HD13  . LEU A 1 285 ? 4.05598   54.35329  18.15334 1.000 143.64243 ? 1068 LEU A HD13  1 
ATOM   3747 H  HD21  . LEU A 1 285 ? 2.95989   52.26321  19.93952 1.000 141.79378 ? 1068 LEU A HD21  1 
ATOM   3748 H  HD22  . LEU A 1 285 ? 4.49663   52.23931  19.53782 1.000 141.79378 ? 1068 LEU A HD22  1 
ATOM   3749 H  HD23  . LEU A 1 285 ? 4.07609   52.24531  21.06969 1.000 141.79378 ? 1068 LEU A HD23  1 
ATOM   3750 N  N     . VAL A 1 286 ? 5.12405   55.82383  23.25203 1.000 111.02608 ? 1069 VAL A N     1 
ATOM   3751 C  CA    . VAL A 1 286 ? 4.51456   56.05839  24.56036 1.000 114.26323 ? 1069 VAL A CA    1 
ATOM   3752 C  C     . VAL A 1 286 ? 4.42900   57.54967  24.85196 1.000 109.67823 ? 1069 VAL A C     1 
ATOM   3753 O  O     . VAL A 1 286 ? 3.43801   58.03377  25.41187 1.000 112.20904 ? 1069 VAL A O     1 
ATOM   3754 C  CB    . VAL A 1 286 ? 5.29148   55.31758  25.66780 1.000 120.77838 ? 1069 VAL A CB    1 
ATOM   3755 C  CG1   . VAL A 1 286 ? 4.93130   53.84225  25.66744 1.000 126.85285 ? 1069 VAL A CG1   1 
ATOM   3756 C  CG2   . VAL A 1 286 ? 6.80066   55.51628  25.51804 1.000 117.45216 ? 1069 VAL A CG2   1 
ATOM   3757 H  H     . VAL A 1 286 ? 5.78661   55.27557  23.25861 1.000 133.27451 ? 1069 VAL A H     1 
ATOM   3758 H  HA    . VAL A 1 286 ? 3.61324   55.70058  24.53807 1.000 137.15909 ? 1069 VAL A HA    1 
ATOM   3759 H  HB    . VAL A 1 286 ? 5.03814   55.69179  26.52610 1.000 144.97727 ? 1069 VAL A HB    1 
ATOM   3760 H  HG11  . VAL A 1 286 ? 5.43895   53.39307  26.36130 1.000 152.26664 ? 1069 VAL A HG11  1 
ATOM   3761 H  HG12  . VAL A 1 286 ? 3.98129   53.74906  25.83975 1.000 152.26664 ? 1069 VAL A HG12  1 
ATOM   3762 H  HG13  . VAL A 1 286 ? 5.14898   53.46424  24.80106 1.000 152.26664 ? 1069 VAL A HG13  1 
ATOM   3763 H  HG21  . VAL A 1 286 ? 7.25135   55.08306  26.25972 1.000 140.98581 ? 1069 VAL A HG21  1 
ATOM   3764 H  HG22  . VAL A 1 286 ? 7.08941   55.12245  24.67993 1.000 140.98581 ? 1069 VAL A HG22  1 
ATOM   3765 H  HG23  . VAL A 1 286 ? 6.99599   56.46640  25.52170 1.000 140.98581 ? 1069 VAL A HG23  1 
ATOM   3766 N  N     . GLY A 1 287 ? 5.46414   58.30186  24.47967 1.000 107.36561 ? 1070 GLY A N     1 
ATOM   3767 C  CA    . GLY A 1 287 ? 5.42844   59.73721  24.70050 1.000 106.15737 ? 1070 GLY A CA    1 
ATOM   3768 C  C     . GLY A 1 287 ? 4.27449   60.40388  23.97846 1.000 108.29365 ? 1070 GLY A C     1 
ATOM   3769 O  O     . GLY A 1 287 ? 3.56896   61.24018  24.54559 1.000 108.41806 ? 1070 GLY A O     1 
ATOM   3770 H  H     . GLY A 1 287 ? 6.18134   58.00941  24.10593 1.000 128.88195 ? 1070 GLY A H     1 
ATOM   3771 H  HA2   . GLY A 1 287 ? 5.33785   59.91380  25.64998 1.000 127.43206 ? 1070 GLY A HA2   1 
ATOM   3772 H  HA3   . GLY A 1 287 ? 6.25606   60.13149  24.38350 1.000 127.43206 ? 1070 GLY A HA3   1 
ATOM   3773 N  N     . GLN A 1 288 ? 4.07445   60.04939  22.70532 1.000 108.99498 ? 1071 GLN A N     1 
ATOM   3774 C  CA    . GLN A 1 288 ? 2.98752   60.64741  21.93618 1.000 110.32382 ? 1071 GLN A CA    1 
ATOM   3775 C  C     . GLN A 1 288 ? 1.62804   60.25155  22.50097 1.000 111.45214 ? 1071 GLN A C     1 
ATOM   3776 O  O     . GLN A 1 288 ? 0.68519   61.05161  22.48020 1.000 112.02772 ? 1071 GLN A O     1 
ATOM   3777 C  CB    . GLN A 1 288 ? 3.10230   60.24247  20.46639 1.000 111.13803 ? 1071 GLN A CB    1 
ATOM   3778 C  CG    . GLN A 1 288 ? 4.39550   60.69429  19.80426 1.000 108.94993 ? 1071 GLN A CG    1 
ATOM   3779 C  CD    . GLN A 1 288 ? 4.27005   60.82670  18.29950 1.000 112.81977 ? 1071 GLN A CD    1 
ATOM   3780 O  OE1   . GLN A 1 288 ? 3.57120   60.04892  17.65021 1.000 116.10961 ? 1071 GLN A OE1   1 
ATOM   3781 N  NE2   . GLN A 1 288 ? 4.94371   61.82400  17.73727 1.000 111.43879 ? 1071 GLN A NE2   1 
ATOM   3782 H  H     . GLN A 1 288 ? 4.54666   59.47501  22.27323 1.000 130.83719 ? 1071 GLN A H     1 
ATOM   3783 H  HA    . GLN A 1 288 ? 3.06155   61.61326  21.98675 1.000 132.43180 ? 1071 GLN A HA    1 
ATOM   3784 H  HB2   . GLN A 1 288 ? 3.06082   59.27528  20.40546 1.000 133.40885 ? 1071 GLN A HB2   1 
ATOM   3785 H  HB3   . GLN A 1 288 ? 2.36478   60.63773  19.97574 1.000 133.40885 ? 1071 GLN A HB3   1 
ATOM   3786 H  HG2   . GLN A 1 288 ? 4.64746   61.56025  20.16138 1.000 130.78313 ? 1071 GLN A HG2   1 
ATOM   3787 H  HG3   . GLN A 1 288 ? 5.09015   60.04353  19.99101 1.000 130.78313 ? 1071 GLN A HG3   1 
ATOM   3788 H  HE21  . GLN A 1 288 ? 5.41762   62.35115  18.22423 1.000 133.76976 ? 1071 GLN A HE21  1 
ATOM   3789 H  HE22  . GLN A 1 288 ? 4.90595   61.94252  16.88631 1.000 133.76976 ? 1071 GLN A HE22  1 
ATOM   3790 N  N     . ILE A 1 289 ? 1.50302   59.02130  23.00515 1.000 113.61944 ? 1072 ILE A N     1 
ATOM   3791 C  CA    . ILE A 1 289 ? 0.27081   58.62923  23.68461 1.000 115.63449 ? 1072 ILE A CA    1 
ATOM   3792 C  C     . ILE A 1 289 ? 0.04397   59.51311  24.90494 1.000 116.60533 ? 1072 ILE A C     1 
ATOM   3793 O  O     . ILE A 1 289 ? -1.07976  59.95835  25.16686 1.000 119.24555 ? 1072 ILE A O     1 
ATOM   3794 C  CB    . ILE A 1 289 ? 0.31389   57.13703  24.06505 1.000 119.44064 ? 1072 ILE A CB    1 
ATOM   3795 C  CG1   . ILE A 1 289 ? -0.00208  56.25028  22.85713 1.000 122.09166 ? 1072 ILE A CG1   1 
ATOM   3796 C  CG2   . ILE A 1 289 ? -0.69256  56.81957  25.16672 1.000 121.62829 ? 1072 ILE A CG2   1 
ATOM   3797 C  CD1   . ILE A 1 289 ? 1.11602   56.12845  21.85929 1.000 116.61461 ? 1072 ILE A CD1   1 
ATOM   3798 H  H     . ILE A 1 289 ? 2.10513   58.40842  22.96725 1.000 136.38655 ? 1072 ILE A H     1 
ATOM   3799 H  HA    . ILE A 1 289 ? -0.47274  58.75573  23.07466 1.000 138.80460 ? 1072 ILE A HA    1 
ATOM   3800 H  HB    . ILE A 1 289 ? 1.21387   56.95709  24.37900 1.000 143.37198 ? 1072 ILE A HB    1 
ATOM   3801 H  HG12  . ILE A 1 289 ? -0.20831  55.35750  23.17543 1.000 146.55321 ? 1072 ILE A HG12  1 
ATOM   3802 H  HG13  . ILE A 1 289 ? -0.76845  56.62242  22.39336 1.000 146.55321 ? 1072 ILE A HG13  1 
ATOM   3803 H  HG21  . ILE A 1 289 ? -0.69004  55.86356  25.33086 1.000 145.99716 ? 1072 ILE A HG21  1 
ATOM   3804 H  HG22  . ILE A 1 289 ? -0.43804  57.29435  25.97338 1.000 145.99716 ? 1072 ILE A HG22  1 
ATOM   3805 H  HG23  . ILE A 1 289 ? -1.57462  57.10364  24.88008 1.000 145.99716 ? 1072 ILE A HG23  1 
ATOM   3806 H  HD11  . ILE A 1 289 ? 0.82961   55.55311  21.13276 1.000 139.98075 ? 1072 ILE A HD11  1 
ATOM   3807 H  HD12  . ILE A 1 289 ? 1.33179   57.01025  21.51756 1.000 139.98075 ? 1072 ILE A HD12  1 
ATOM   3808 H  HD13  . ILE A 1 289 ? 1.89118   55.74524  22.29881 1.000 139.98075 ? 1072 ILE A HD13  1 
ATOM   3809 N  N     . ASP A 1 290 ? 1.10638   59.78211  25.67041 1.000 115.85349 ? 1073 ASP A N     1 
ATOM   3810 C  CA    . ASP A 1 290 ? 0.97186   60.63867  26.84499 1.000 117.24112 ? 1073 ASP A CA    1 
ATOM   3811 C  C     . ASP A 1 290 ? 0.54024   62.04655  26.45356 1.000 117.71339 ? 1073 ASP A C     1 
ATOM   3812 O  O     . ASP A 1 290 ? -0.29653  62.65762  27.12865 1.000 119.35430 ? 1073 ASP A O     1 
ATOM   3813 C  CB    . ASP A 1 290 ? 2.28882   60.67902  27.62171 1.000 120.27834 ? 1073 ASP A CB    1 
ATOM   3814 C  CG    . ASP A 1 290 ? 2.50625   59.43836  28.46870 1.000 122.88044 ? 1073 ASP A CG    1 
ATOM   3815 O  OD1   . ASP A 1 290 ? 1.59496   58.58593  28.52489 1.000 125.65195 ? 1073 ASP A OD1   1 
ATOM   3816 O  OD2   . ASP A 1 290 ? 3.58849   59.31632  29.08087 1.000 117.41680 ? 1073 ASP A OD2   1 
ATOM   3817 H  H     . ASP A 1 290 ? 1.90156   59.48521  25.53203 1.000 139.06741 ? 1073 ASP A H     1 
ATOM   3818 H  HA    . ASP A 1 290 ? 0.29167   60.26480  27.42677 1.000 140.73256 ? 1073 ASP A HA    1 
ATOM   3819 H  HB2   . ASP A 1 290 ? 3.02482   60.74663  26.99352 1.000 144.37723 ? 1073 ASP A HB2   1 
ATOM   3820 H  HB3   . ASP A 1 290 ? 2.28468   61.44875  28.21197 1.000 144.37723 ? 1073 ASP A HB3   1 
ATOM   3821 N  N     . ASP A 1 291 ? 1.10432   62.58118  25.36838 1.000 116.48826 ? 1074 ASP A N     1 
ATOM   3822 C  CA    . ASP A 1 291 ? 0.68672   63.89476  24.88973 1.000 116.21842 ? 1074 ASP A CA    1 
ATOM   3823 C  C     . ASP A 1 291 ? -0.80799  63.91407  24.59461 1.000 119.24505 ? 1074 ASP A C     1 
ATOM   3824 O  O     . ASP A 1 291 ? -1.54148  64.78047  25.08520 1.000 121.84912 ? 1074 ASP A O     1 
ATOM   3825 C  CB    . ASP A 1 291 ? 1.48295   64.27392  23.64033 1.000 113.37404 ? 1074 ASP A CB    1 
ATOM   3826 C  CG    . ASP A 1 291 ? 2.97355   64.34701  23.89716 1.000 103.96543 ? 1074 ASP A CG    1 
ATOM   3827 O  OD1   . ASP A 1 291 ? 3.38471   64.23201  25.07073 1.000 102.74695 ? 1074 ASP A OD1   1 
ATOM   3828 O  OD2   . ASP A 1 291 ? 3.73466   64.51742  22.92202 1.000 101.33828 ? 1074 ASP A OD2   1 
ATOM   3829 H  H     . ASP A 1 291 ? 1.72139   62.20825  24.89961 1.000 139.82913 ? 1074 ASP A H     1 
ATOM   3830 H  HA    . ASP A 1 291 ? 0.87164   64.55312  25.57766 1.000 139.50531 ? 1074 ASP A HA    1 
ATOM   3831 H  HB2   . ASP A 1 291 ? 1.32915   63.60718  22.95279 1.000 136.09207 ? 1074 ASP A HB2   1 
ATOM   3832 H  HB3   . ASP A 1 291 ? 1.18879   65.14455  23.32990 1.000 136.09207 ? 1074 ASP A HB3   1 
ATOM   3833 N  N     . ALA A 1 292 ? -1.27838  62.95616  23.79259 1.000 124.00647 ? 1075 ALA A N     1 
ATOM   3834 C  CA    . ALA A 1 292 ? -2.69190  62.91481  23.43858 1.000 123.27043 ? 1075 ALA A CA    1 
ATOM   3835 C  C     . ALA A 1 292 ? -3.57028  62.64554  24.65360 1.000 123.91956 ? 1075 ALA A C     1 
ATOM   3836 O  O     . ALA A 1 292 ? -4.68958  63.16448  24.73392 1.000 126.38905 ? 1075 ALA A O     1 
ATOM   3837 C  CB    . ALA A 1 292 ? -2.92989  61.85039  22.36751 1.000 126.09423 ? 1075 ALA A CB    1 
ATOM   3838 H  H     . ALA A 1 292 ? -0.80445  62.32784  23.44588 1.000 148.85098 ? 1075 ALA A H     1 
ATOM   3839 H  HA    . ALA A 1 292 ? -2.94642  63.77592  23.07170 1.000 147.96773 ? 1075 ALA A HA    1 
ATOM   3840 H  HB1   . ALA A 1 292 ? -3.87436  61.82947  22.14744 1.000 151.35629 ? 1075 ALA A HB1   1 
ATOM   3841 H  HB2   . ALA A 1 292 ? -2.41139  62.07442  21.57893 1.000 151.35629 ? 1075 ALA A HB2   1 
ATOM   3842 H  HB3   . ALA A 1 292 ? -2.65142  60.98758  22.71236 1.000 151.35629 ? 1075 ALA A HB3   1 
ATOM   3843 N  N     . LEU A 1 293 ? -3.08741  61.84460  25.60490 1.000 124.68018 ? 1076 LEU A N     1 
ATOM   3844 C  CA    . LEU A 1 293 ? -3.89622  61.52913  26.77825 1.000 126.52401 ? 1076 LEU A CA    1 
ATOM   3845 C  C     . LEU A 1 293 ? -4.01227  62.73363  27.70376 1.000 128.50092 ? 1076 LEU A C     1 
ATOM   3846 O  O     . LEU A 1 293 ? -5.07804  62.97970  28.28073 1.000 130.99529 ? 1076 LEU A O     1 
ATOM   3847 C  CB    . LEU A 1 293 ? -3.29772  60.33300  27.51725 1.000 124.63295 ? 1076 LEU A CB    1 
ATOM   3848 C  CG    . LEU A 1 293 ? -4.22380  59.56310  28.46203 1.000 130.62889 ? 1076 LEU A CG    1 
ATOM   3849 C  CD1   . LEU A 1 293 ? -5.49752  59.13404  27.74821 1.000 129.75785 ? 1076 LEU A CD1   1 
ATOM   3850 C  CD2   . LEU A 1 293 ? -3.49825  58.35441  29.03964 1.000 130.64650 ? 1076 LEU A CD2   1 
ATOM   3851 H  H     . LEU A 1 293 ? -2.30935  61.47840  25.59434 1.000 149.65943 ? 1076 LEU A H     1 
ATOM   3852 H  HA    . LEU A 1 293 ? -4.79002  61.28548  26.49074 1.000 151.87202 ? 1076 LEU A HA    1 
ATOM   3853 H  HB2   . LEU A 1 293 ? -2.98176  59.70014  26.85351 1.000 149.60275 ? 1076 LEU A HB2   1 
ATOM   3854 H  HB3   . LEU A 1 293 ? -2.55359  60.65385  28.05039 1.000 149.60275 ? 1076 LEU A HB3   1 
ATOM   3855 H  HG    . LEU A 1 293 ? -4.48082  60.14517  29.19417 1.000 156.79788 ? 1076 LEU A HG    1 
ATOM   3856 H  HD11  . LEU A 1 293 ? -6.21747  59.73372  27.99914 1.000 155.75263 ? 1076 LEU A HD11  1 
ATOM   3857 H  HD12  . LEU A 1 293 ? -5.35169  59.17499  26.79011 1.000 155.75263 ? 1076 LEU A HD12  1 
ATOM   3858 H  HD13  . LEU A 1 293 ? -5.71634  58.22632  28.01099 1.000 155.75263 ? 1076 LEU A HD13  1 
ATOM   3859 H  HD21  . LEU A 1 293 ? -4.14555  57.77221  29.46737 1.000 156.81902 ? 1076 LEU A HD21  1 
ATOM   3860 H  HD22  . LEU A 1 293 ? -3.05173  57.88074  28.32051 1.000 156.81902 ? 1076 LEU A HD22  1 
ATOM   3861 H  HD23  . LEU A 1 293 ? -2.84628  58.65863  29.69024 1.000 156.81902 ? 1076 LEU A HD23  1 
ATOM   3862 N  N     . LYS A 1 294 ? -2.92805  63.49619  27.85830 1.000 127.91770 ? 1077 LYS A N     1 
ATOM   3863 C  CA    . LYS A 1 294 ? -2.99348  64.71632  28.65476 1.000 129.21821 ? 1077 LYS A CA    1 
ATOM   3864 C  C     . LYS A 1 294 ? -3.96011  65.71306  28.03024 1.000 128.74511 ? 1077 LYS A C     1 
ATOM   3865 O  O     . LYS A 1 294 ? -4.79015  66.31285  28.72261 1.000 132.40708 ? 1077 LYS A O     1 
ATOM   3866 C  CB    . LYS A 1 294 ? -1.59905  65.32859  28.78965 1.000 129.61163 ? 1077 LYS A CB    1 
ATOM   3867 H  H     . LYS A 1 294 ? -2.15610  63.33049  27.51737 1.000 153.54446 ? 1077 LYS A H     1 
ATOM   3868 H  HA    . LYS A 1 294 ? -3.31125  64.49807  29.54487 1.000 155.10507 ? 1077 LYS A HA    1 
ATOM   3869 N  N     . LEU A 1 295 ? -3.87299  65.89166  26.71090 1.000 128.03611 ? 1078 LEU A N     1 
ATOM   3870 C  CA    . LEU A 1 295 ? -4.76000  66.82594  26.03008 1.000 133.22891 ? 1078 LEU A CA    1 
ATOM   3871 C  C     . LEU A 1 295 ? -6.20417  66.34286  26.04723 1.000 130.77315 ? 1078 LEU A C     1 
ATOM   3872 O  O     . LEU A 1 295 ? -7.12994  67.16155  26.01280 1.000 132.95825 ? 1078 LEU A O     1 
ATOM   3873 C  CB    . LEU A 1 295 ? -4.28716  67.03095  24.59539 1.000 133.97217 ? 1078 LEU A CB    1 
ATOM   3874 C  CG    . LEU A 1 295 ? -4.70366  68.34363  23.93985 1.000 139.79343 ? 1078 LEU A CG    1 
ATOM   3875 C  CD1   . LEU A 1 295 ? -3.87003  69.51718  24.41805 1.000 135.42915 ? 1078 LEU A CD1   1 
ATOM   3876 C  CD2   . LEU A 1 295 ? -4.57962  68.18679  22.44684 1.000 146.34241 ? 1078 LEU A CD2   1 
ATOM   3877 H  H     . LEU A 1 295 ? -3.31521  65.48817  26.19546 1.000 153.68655 ? 1078 LEU A H     1 
ATOM   3878 H  HA    . LEU A 1 295 ? -4.72737  67.68148  26.48603 1.000 159.91791 ? 1078 LEU A HA    1 
ATOM   3879 H  HB2   . LEU A 1 295 ? -3.31766  67.00051  24.58849 1.000 160.80982 ? 1078 LEU A HB2   1 
ATOM   3880 H  HB3   . LEU A 1 295 ? -4.64554  66.31148  24.05240 1.000 160.80982 ? 1078 LEU A HB3   1 
ATOM   3881 H  HG    . LEU A 1 295 ? -5.62048  68.54547  24.18398 1.000 167.79533 ? 1078 LEU A HG    1 
ATOM   3882 H  HD11  . LEU A 1 295 ? -4.18658  70.32611  23.98639 1.000 162.55820 ? 1078 LEU A HD11  1 
ATOM   3883 H  HD12  . LEU A 1 295 ? -3.96150  69.59823  25.38032 1.000 162.55820 ? 1078 LEU A HD12  1 
ATOM   3884 H  HD13  . LEU A 1 295 ? -2.94135  69.36018  24.18611 1.000 162.55820 ? 1078 LEU A HD13  1 
ATOM   3885 H  HD21  . LEU A 1 295 ? -4.77082  69.03805  22.02291 1.000 175.65410 ? 1078 LEU A HD21  1 
ATOM   3886 H  HD22  . LEU A 1 295 ? -3.67611  67.90620  22.23276 1.000 175.65410 ? 1078 LEU A HD22  1 
ATOM   3887 H  HD23  . LEU A 1 295 ? -5.21392  67.51750  22.14583 1.000 175.65410 ? 1078 LEU A HD23  1 
ATOM   3888 N  N     . ALA A 1 296 ? -6.41828  65.02535  26.08833 1.000 132.83356 ? 1079 ALA A N     1 
ATOM   3889 C  CA    . ALA A 1 296 ? -7.77300  64.50548  26.23471 1.000 132.14653 ? 1079 ALA A CA    1 
ATOM   3890 C  C     . ALA A 1 296 ? -8.28634  64.69542  27.65561 1.000 135.10010 ? 1079 ALA A C     1 
ATOM   3891 O  O     . ALA A 1 296 ? -9.49482  64.85295  27.86192 1.000 135.43999 ? 1079 ALA A O     1 
ATOM   3892 C  CB    . ALA A 1 296 ? -7.81624  63.02815  25.84552 1.000 132.92715 ? 1079 ALA A CB    1 
ATOM   3893 H  H     . ALA A 1 296 ? -5.80595  64.42391  26.03433 1.000 159.44348 ? 1079 ALA A H     1 
ATOM   3894 H  HA    . ALA A 1 296 ? -8.36178  64.98672  25.63251 1.000 158.61905 ? 1079 ALA A HA    1 
ATOM   3895 H  HB1   . ALA A 1 296 ? -8.71827  62.69456  25.97187 1.000 159.55580 ? 1079 ALA A HB1   1 
ATOM   3896 H  HB2   . ALA A 1 296 ? -7.55797  62.93908  24.91478 1.000 159.55580 ? 1079 ALA A HB2   1 
ATOM   3897 H  HB3   . ALA A 1 296 ? -7.19929  62.53503  26.40864 1.000 159.55580 ? 1079 ALA A HB3   1 
ATOM   3898 N  N     . ASN A 1 297 ? -7.38893  64.68304  28.64415 1.000 137.14639 ? 1080 ASN A N     1 
ATOM   3899 C  CA    . ASN A 1 297 ? -7.78720  64.97919  30.01394 1.000 139.96657 ? 1080 ASN A CA    1 
ATOM   3900 C  C     . ASN A 1 297 ? -8.13866  66.44893  30.19997 1.000 135.82886 ? 1080 ASN A C     1 
ATOM   3901 O  O     . ASN A 1 297 ? -8.87034  66.78471  31.13723 1.000 139.56065 ? 1080 ASN A O     1 
ATOM   3902 C  CB    . ASN A 1 297 ? -6.67134  64.58564  30.98282 1.000 134.98679 ? 1080 ASN A CB    1 
ATOM   3903 H  H     . ASN A 1 297 ? -6.55277  64.50766  28.54579 1.000 164.61888 ? 1080 ASN A H     1 
ATOM   3904 H  HA    . ASN A 1 297 ? -8.57094  64.45133  30.23305 1.000 168.00311 ? 1080 ASN A HA    1 
ATOM   3905 N  N     . GLU A 1 298 ? -7.63601  67.32725  29.33320 1.000 139.16826 ? 1081 GLU A N     1 
ATOM   3906 C  CA    . GLU A 1 298 ? -7.95819  68.74653  29.38313 1.000 143.31132 ? 1081 GLU A CA    1 
ATOM   3907 C  C     . GLU A 1 298 ? -9.25425  69.08257  28.65549 1.000 140.39512 ? 1081 GLU A C     1 
ATOM   3908 O  O     . GLU A 1 298 ? -9.56938  70.26722  28.49814 1.000 138.47372 ? 1081 GLU A O     1 
ATOM   3909 C  CB    . GLU A 1 298 ? -6.81253  69.56992  28.78479 1.000 142.19097 ? 1081 GLU A CB    1 
ATOM   3910 C  CG    . GLU A 1 298 ? -5.44886  69.27249  29.38462 1.000 144.18772 ? 1081 GLU A CG    1 
ATOM   3911 C  CD    . GLU A 1 298 ? -4.59040  70.51436  29.52611 1.000 145.02865 ? 1081 GLU A CD    1 
ATOM   3912 O  OE1   . GLU A 1 298 ? -4.70806  71.42293  28.67729 1.000 143.13183 ? 1081 GLU A OE1   1 
ATOM   3913 O  OE2   . GLU A 1 298 ? -3.80374  70.58496  30.49386 1.000 137.40472 ? 1081 GLU A OE2   1 
ATOM   3914 H  H     . GLU A 1 298 ? -7.09661  67.11875  28.69666 1.000 167.04513 ? 1081 GLU A H     1 
ATOM   3915 H  HA    . GLU A 1 298 ? -8.05882  69.00251  30.31332 1.000 172.01680 ? 1081 GLU A HA    1 
ATOM   3916 H  HB2   . GLU A 1 298 ? -6.76193  69.38485  27.83396 1.000 170.67238 ? 1081 GLU A HB2   1 
ATOM   3917 H  HB3   . GLU A 1 298 ? -6.99857  70.51074  28.93022 1.000 170.67238 ? 1081 GLU A HB3   1 
ATOM   3918 H  HG2   . GLU A 1 298 ? -5.56821  68.88757  30.26695 1.000 173.06848 ? 1081 GLU A HG2   1 
ATOM   3919 H  HG3   . GLU A 1 298 ? -4.98002  68.64691  28.81040 1.000 173.06848 ? 1081 GLU A HG3   1 
ATOM   3920 N  N     . GLY A 1 299 ? -10.00604 68.07843  28.20864 1.000 138.15488 ? 1082 GLY A N     1 
ATOM   3921 C  CA    . GLY A 1 299 ? -11.21534 68.33063  27.45348 1.000 134.90444 ? 1082 GLY A CA    1 
ATOM   3922 C  C     . GLY A 1 299 ? -10.99015 68.85322  26.05496 1.000 131.86172 ? 1082 GLY A C     1 
ATOM   3923 O  O     . GLY A 1 299 ? -11.95880 69.19723  25.37143 1.000 127.52002 ? 1082 GLY A O     1 
ATOM   3924 H  H     . GLY A 1 299 ? -9.83245  67.24530  28.33255 1.000 165.82907 ? 1082 GLY A H     1 
ATOM   3925 H  HA2   . GLY A 1 299 ? -11.71644 67.50305  27.38341 1.000 161.92854 ? 1082 GLY A HA2   1 
ATOM   3926 H  HA3   . GLY A 1 299 ? -11.74982 68.98393  27.93141 1.000 161.92854 ? 1082 GLY A HA3   1 
ATOM   3927 N  N     . LYS A 1 300 ? -9.73967  68.92740  25.60581 1.000 133.60085 ? 1083 LYS A N     1 
ATOM   3928 C  CA    . LYS A 1 300 ? -9.42474  69.37546  24.25245 1.000 132.11221 ? 1083 LYS A CA    1 
ATOM   3929 C  C     . LYS A 1 300 ? -9.55687  68.16177  23.34052 1.000 133.92982 ? 1083 LYS A C     1 
ATOM   3930 O  O     . LYS A 1 300 ? -8.57703  67.53028  22.93717 1.000 138.26636 ? 1083 LYS A O     1 
ATOM   3931 C  CB    . LYS A 1 300 ? -8.03174  69.98605  24.19380 1.000 132.70953 ? 1083 LYS A CB    1 
ATOM   3932 H  H     . LYS A 1 300 ? -9.04739  68.72084  26.07238 1.000 160.36424 ? 1083 LYS A H     1 
ATOM   3933 H  HA    . LYS A 1 300 ? -10.05340 70.05832  23.97068 1.000 158.57787 ? 1083 LYS A HA    1 
ATOM   3934 N  N     . VAL A 1 301 ? -10.79986 67.81097  23.02499 1.000 134.04456 ? 1084 VAL A N     1 
ATOM   3935 C  CA    . VAL A 1 301 ? -11.05217 66.61619  22.22858 1.000 134.41910 ? 1084 VAL A CA    1 
ATOM   3936 C  C     . VAL A 1 301 ? -10.29990 66.72061  20.90035 1.000 136.88475 ? 1084 VAL A C     1 
ATOM   3937 O  O     . VAL A 1 301 ? -9.30998  66.01577  20.68494 1.000 140.87281 ? 1084 VAL A O     1 
ATOM   3938 C  CB    . VAL A 1 301 ? -12.56317 66.40663  22.00630 1.000 135.01573 ? 1084 VAL A CB    1 
ATOM   3939 C  CG1   . VAL A 1 301 ? -12.87095 64.96408  21.60474 1.000 135.73499 ? 1084 VAL A CG1   1 
ATOM   3940 C  CG2   . VAL A 1 301 ? -13.35681 66.78369  23.27313 1.000 135.45725 ? 1084 VAL A CG2   1 
ATOM   3941 H  H     . VAL A 1 301 ? -11.50545 68.24398  23.25791 1.000 160.89669 ? 1084 VAL A H     1 
ATOM   3942 H  HA    . VAL A 1 301 ? -10.70877 65.84250  22.70228 1.000 161.34614 ? 1084 VAL A HA    1 
ATOM   3943 H  HB    . VAL A 1 301 ? -12.84230 66.98624  21.28032 1.000 162.06209 ? 1084 VAL A HB    1 
ATOM   3944 H  HG11  . VAL A 1 301 ? -13.55971 64.61324  22.19076 1.000 162.92521 ? 1084 VAL A HG11  1 
ATOM   3945 H  HG12  . VAL A 1 301 ? -13.18066 64.95136  20.68560 1.000 162.92521 ? 1084 VAL A HG12  1 
ATOM   3946 H  HG13  . VAL A 1 301 ? -12.06322 64.43363  21.68899 1.000 162.92521 ? 1084 VAL A HG13  1 
ATOM   3947 H  HG21  . VAL A 1 301 ? -14.19496 66.29545  23.27769 1.000 162.59192 ? 1084 VAL A HG21  1 
ATOM   3948 H  HG22  . VAL A 1 301 ? -12.83317 66.54925  24.05528 1.000 162.59192 ? 1084 VAL A HG22  1 
ATOM   3949 H  HG23  . VAL A 1 301 ? -13.52998 67.73807  23.26491 1.000 162.59192 ? 1084 VAL A HG23  1 
ATOM   3950 N  N     . LYS A 1 302 ? -10.71657 67.65869  20.04991 1.000 136.58595 ? 1085 LYS A N     1 
ATOM   3951 C  CA    . LYS A 1 302 ? -10.21702 67.74099  18.67763 1.000 134.94788 ? 1085 LYS A CA    1 
ATOM   3952 C  C     . LYS A 1 302 ? -8.69534  67.68764  18.59191 1.000 140.18351 ? 1085 LYS A C     1 
ATOM   3953 O  O     . LYS A 1 302 ? -8.12934  66.87563  17.85141 1.000 141.67439 ? 1085 LYS A O     1 
ATOM   3954 C  CB    . LYS A 1 302 ? -10.72634 69.02707  18.03032 1.000 123.08345 ? 1085 LYS A CB    1 
ATOM   3955 C  CG    . LYS A 1 302 ? -12.18711 68.98433  17.68414 1.000 110.16134 ? 1085 LYS A CG    1 
ATOM   3956 C  CD    . LYS A 1 302 ? -12.43467 68.06217  16.50948 1.000 113.91429 ? 1085 LYS A CD    1 
ATOM   3957 C  CE    . LYS A 1 302 ? -13.87086 68.15334  16.04484 1.000 107.77088 ? 1085 LYS A CE    1 
ATOM   3958 N  NZ    . LYS A 1 302 ? -14.08610 67.37548  14.79815 1.000 129.13914 ? 1085 LYS A NZ    1 
ATOM   3959 H  H     . LYS A 1 302 ? -11.29386 68.26585  20.24405 1.000 163.94636 ? 1085 LYS A H     1 
ATOM   3960 H  HA    . LYS A 1 302 ? -10.55905 66.97143  18.19627 1.000 161.98068 ? 1085 LYS A HA    1 
ATOM   3961 H  HB2   . LYS A 1 302 ? -10.58811 69.76348  18.64635 1.000 147.74335 ? 1085 LYS A HB2   1 
ATOM   3962 H  HB3   . LYS A 1 302 ? -10.23094 69.18249  17.21098 1.000 147.74335 ? 1085 LYS A HB3   1 
ATOM   3963 H  HG2   . LYS A 1 302 ? -12.69086 68.65549  18.44506 1.000 132.23682 ? 1085 LYS A HG2   1 
ATOM   3964 H  HG3   . LYS A 1 302 ? -12.48967 69.87455  17.44563 1.000 132.23682 ? 1085 LYS A HG3   1 
ATOM   3965 H  HD2   . LYS A 1 302 ? -11.85665 68.31462  15.77255 1.000 136.74037 ? 1085 LYS A HD2   1 
ATOM   3966 H  HD3   . LYS A 1 302 ? -12.25468 67.14634  16.77360 1.000 136.74037 ? 1085 LYS A HD3   1 
ATOM   3967 H  HE2   . LYS A 1 302 ? -14.45470 67.79656  16.73240 1.000 129.36827 ? 1085 LYS A HE2   1 
ATOM   3968 H  HE3   . LYS A 1 302 ? -14.09377 69.08082  15.86879 1.000 129.36827 ? 1085 LYS A HE3   1 
ATOM   3969 H  HZ1   . LYS A 1 302 ? -14.94152 67.41862  14.55630 1.000 155.01018 ? 1085 LYS A HZ1   1 
ATOM   3970 H  HZ2   . LYS A 1 302 ? -13.58350 67.70629  14.14236 1.000 155.01018 ? 1085 LYS A HZ2   1 
ATOM   3971 H  HZ3   . LYS A 1 302 ? -13.86562 66.52324  14.92921 1.000 155.01018 ? 1085 LYS A HZ3   1 
ATOM   3972 N  N     . GLU A 1 303 ? -8.01054  68.57680  19.30654 1.000 146.39987 ? 1086 GLU A N     1 
ATOM   3973 C  CA    . GLU A 1 303 ? -6.55463  68.56948  19.24157 1.000 172.81068 ? 1086 GLU A CA    1 
ATOM   3974 C  C     . GLU A 1 303 ? -5.97435  67.24702  19.73123 1.000 151.85906 ? 1086 GLU A C     1 
ATOM   3975 O  O     . GLU A 1 303 ? -4.81750  66.93759  19.42282 1.000 148.05068 ? 1086 GLU A O     1 
ATOM   3976 C  CB    . GLU A 1 303 ? -5.99603  69.74492  20.04290 1.000 200.82068 ? 1086 GLU A CB    1 
ATOM   3977 H  H     . GLU A 1 303 ? -8.35430  69.17505  19.81989 1.000 175.72306 ? 1086 GLU A H     1 
ATOM   3978 H  HA    . GLU A 1 303 ? -6.26926  68.68727  18.32201 1.000 207.41603 ? 1086 GLU A HA    1 
ATOM   3979 N  N     . ALA A 1 304 ? -6.74968  66.45435  20.47889 1.000 148.75013 ? 1087 ALA A N     1 
ATOM   3980 C  CA    . ALA A 1 304 ? -6.26555  65.15116  20.92060 1.000 141.40308 ? 1087 ALA A CA    1 
ATOM   3981 C  C     . ALA A 1 304 ? -6.27152  64.12082  19.79328 1.000 139.39181 ? 1087 ALA A C     1 
ATOM   3982 O  O     . ALA A 1 304 ? -5.39265  63.25177  19.75710 1.000 144.48269 ? 1087 ALA A O     1 
ATOM   3983 C  CB    . ALA A 1 304 ? -7.10008  64.64619  22.10034 1.000 139.02926 ? 1087 ALA A CB    1 
ATOM   3984 H  H     . ALA A 1 304 ? -7.54659  66.64781  20.73796 1.000 178.54338 ? 1087 ALA A H     1 
ATOM   3985 H  HA    . ALA A 1 304 ? -5.35046  65.25104  21.22643 1.000 169.72691 ? 1087 ALA A HA    1 
ATOM   3986 H  HB1   . ALA A 1 304 ? -6.69426  63.83808  22.45128 1.000 166.87833 ? 1087 ALA A HB1   1 
ATOM   3987 H  HB2   . ALA A 1 304 ? -7.12213  65.33054  22.78743 1.000 166.87833 ? 1087 ALA A HB2   1 
ATOM   3988 H  HB3   . ALA A 1 304 ? -8.00035  64.45744  21.79247 1.000 166.87833 ? 1087 ALA A HB3   1 
ATOM   3989 N  N     . GLN A 1 305 ? -7.23494  64.18593  18.86734 1.000 138.89019 ? 1088 GLN A N     1 
ATOM   3990 C  CA    . GLN A 1 305 ? -7.17622  63.28331  17.72061 1.000 137.56322 ? 1088 GLN A CA    1 
ATOM   3991 C  C     . GLN A 1 305 ? -5.99083  63.62765  16.82805 1.000 141.32892 ? 1088 GLN A C     1 
ATOM   3992 O  O     . GLN A 1 305 ? -5.32753  62.73392  16.29003 1.000 138.03010 ? 1088 GLN A O     1 
ATOM   3993 C  CB    . GLN A 1 305 ? -8.46491  63.33221  16.89612 1.000 140.60113 ? 1088 GLN A CB    1 
ATOM   3994 C  CG    . GLN A 1 305 ? -9.75559  63.00852  17.64191 1.000 139.10826 ? 1088 GLN A CG    1 
ATOM   3995 C  CD    . GLN A 1 305 ? -10.22589 64.16579  18.47989 1.000 140.59800 ? 1088 GLN A CD    1 
ATOM   3996 O  OE1   . GLN A 1 305 ? -9.46360  65.07790  18.71914 1.000 141.99174 ? 1088 GLN A OE1   1 
ATOM   3997 N  NE2   . GLN A 1 305 ? -11.47760 64.13839  18.92180 1.000 138.78319 ? 1088 GLN A NE2   1 
ATOM   3998 H  H     . GLN A 1 305 ? -7.90606  64.72352  18.88135 1.000 166.71145 ? 1088 GLN A H     1 
ATOM   3999 H  HA    . GLN A 1 305 ? -7.08159  62.37971  18.06039 1.000 165.11908 ? 1088 GLN A HA    1 
ATOM   4000 H  HB2   . GLN A 1 305 ? -8.55986  64.22820  16.53684 1.000 168.76457 ? 1088 GLN A HB2   1 
ATOM   4001 H  HB3   . GLN A 1 305 ? -8.38501  62.69131  16.17240 1.000 168.76457 ? 1088 GLN A HB3   1 
ATOM   4002 H  HG2   . GLN A 1 305 ? -10.45090 62.79672  16.99959 1.000 166.97313 ? 1088 GLN A HG2   1 
ATOM   4003 H  HG3   . GLN A 1 305 ? -9.60394  62.25104  18.22853 1.000 166.97313 ? 1088 GLN A HG3   1 
ATOM   4004 H  HE21  . GLN A 1 305 ? -11.98816 63.47451  18.72641 1.000 166.58304 ? 1088 GLN A HE21  1 
ATOM   4005 H  HE22  . GLN A 1 305 ? -11.77780 64.78454  19.40343 1.000 166.58304 ? 1088 GLN A HE22  1 
ATOM   4006 N  N     . ALA A 1 306 ? -5.72083  64.92244  16.64837 1.000 141.17404 ? 1089 ALA A N     1 
ATOM   4007 C  CA    . ALA A 1 306 ? -4.54920  65.33562  15.88567 1.000 138.54482 ? 1089 ALA A CA    1 
ATOM   4008 C  C     . ALA A 1 306 ? -3.27505  64.80847  16.53114 1.000 137.90823 ? 1089 ALA A C     1 
ATOM   4009 O  O     . ALA A 1 306 ? -2.41435  64.22945  15.85781 1.000 141.82725 ? 1089 ALA A O     1 
ATOM   4010 C  CB    . ALA A 1 306 ? -4.51010  66.86014  15.77514 1.000 149.53068 ? 1089 ALA A CB    1 
ATOM   4011 H  H     . ALA A 1 306 ? -6.19530  65.57107  16.95458 1.000 169.45207 ? 1089 ALA A H     1 
ATOM   4012 H  HA    . ALA A 1 306 ? -4.60874  64.97240  14.98821 1.000 166.29700 ? 1089 ALA A HA    1 
ATOM   4013 H  HB1   . ALA A 1 306 ? -3.73426  67.11917  15.25372 1.000 179.48003 ? 1089 ALA A HB1   1 
ATOM   4014 H  HB2   . ALA A 1 306 ? -5.31992  67.16591  15.33743 1.000 179.48003 ? 1089 ALA A HB2   1 
ATOM   4015 H  HB3   . ALA A 1 306 ? -4.45188  67.23995  16.66579 1.000 179.48003 ? 1089 ALA A HB3   1 
ATOM   4016 N  N     . ALA A 1 307 ? -3.14292  64.99431  17.84717 1.000 138.04591 ? 1090 ALA A N     1 
ATOM   4017 C  CA    . ALA A 1 307 ? -1.97207  64.48438  18.55024 1.000 139.85903 ? 1090 ALA A CA    1 
ATOM   4018 C  C     . ALA A 1 307 ? -1.89616  62.96618  18.47510 1.000 136.97784 ? 1090 ALA A C     1 
ATOM   4019 O  O     . ALA A 1 307 ? -0.79712  62.40053  18.46100 1.000 136.03267 ? 1090 ALA A O     1 
ATOM   4020 C  CB    . ALA A 1 307 ? -1.99237  64.94305  20.00837 1.000 142.76574 ? 1090 ALA A CB    1 
ATOM   4021 H  H     . ALA A 1 307 ? -3.70952  65.40623  18.34607 1.000 165.69830 ? 1090 ALA A H     1 
ATOM   4022 H  HA    . ALA A 1 307 ? -1.17471  64.84764  18.13412 1.000 167.87406 ? 1090 ALA A HA    1 
ATOM   4023 H  HB1   . ALA A 1 307 ? -1.20009  64.60729  20.45610 1.000 171.36211 ? 1090 ALA A HB1   1 
ATOM   4024 H  HB2   . ALA A 1 307 ? -2.00111  65.91266  20.03433 1.000 171.36211 ? 1090 ALA A HB2   1 
ATOM   4025 H  HB3   . ALA A 1 307 ? -2.78849  64.59345  20.43834 1.000 171.36211 ? 1090 ALA A HB3   1 
ATOM   4026 N  N     . ALA A 1 308 ? -3.04494  62.28886  18.42994 1.000 137.55042 ? 1091 ALA A N     1 
ATOM   4027 C  CA    . ALA A 1 308 ? -3.03988  60.84103  18.25903 1.000 139.28274 ? 1091 ALA A CA    1 
ATOM   4028 C  C     . ALA A 1 308 ? -2.77274  60.44289  16.81265 1.000 137.55378 ? 1091 ALA A C     1 
ATOM   4029 O  O     . ALA A 1 308 ? -2.20810  59.37150  16.56415 1.000 141.54194 ? 1091 ALA A O     1 
ATOM   4030 C  CB    . ALA A 1 308 ? -4.36885  60.24899  18.72977 1.000 135.68068 ? 1091 ALA A CB    1 
ATOM   4031 H  H     . ALA A 1 308 ? -3.82704  62.64054  18.49506 1.000 165.10372 ? 1091 ALA A H     1 
ATOM   4032 H  HA    . ALA A 1 308 ? -2.33640  60.46381  18.81014 1.000 167.18250 ? 1091 ALA A HA    1 
ATOM   4033 H  HB1   . ALA A 1 308 ? -4.34064  59.28527  18.62322 1.000 162.86003 ? 1091 ALA A HB1   1 
ATOM   4034 H  HB2   . ALA A 1 308 ? -4.50200  60.47477  19.66368 1.000 162.86003 ? 1091 ALA A HB2   1 
ATOM   4035 H  HB3   . ALA A 1 308 ? -5.08731  60.62011  18.19406 1.000 162.86003 ? 1091 ALA A HB3   1 
ATOM   4036 N  N     . GLU A 1 309 ? -3.16796  61.28401  15.85276 1.000 136.81937 ? 1092 GLU A N     1 
ATOM   4037 C  CA    . GLU A 1 309 ? -2.88320  61.00741  14.45074 1.000 136.80389 ? 1092 GLU A CA    1 
ATOM   4038 C  C     . GLU A 1 309 ? -1.39298  61.07236  14.15488 1.000 133.62454 ? 1092 GLU A C     1 
ATOM   4039 O  O     . GLU A 1 309 ? -0.94476  60.48890  13.16149 1.000 130.80547 ? 1092 GLU A O     1 
ATOM   4040 C  CB    . GLU A 1 309 ? -3.63235  61.99461  13.55620 1.000 139.93507 ? 1092 GLU A CB    1 
ATOM   4041 C  CG    . GLU A 1 309 ? -4.20108  61.37285  12.29452 1.000 142.30890 ? 1092 GLU A CG    1 
ATOM   4042 C  CD    . GLU A 1 309 ? -5.29594  60.36423  12.58855 1.000 139.62244 ? 1092 GLU A CD    1 
ATOM   4043 O  OE1   . GLU A 1 309 ? -5.73125  60.27898  13.75684 1.000 136.74677 ? 1092 GLU A OE1   1 
ATOM   4044 O  OE2   . GLU A 1 309 ? -5.71865  59.65406  11.65272 1.000 142.94149 ? 1092 GLU A OE2   1 
ATOM   4045 H  H     . GLU A 1 309 ? -3.59917  62.01540  15.98962 1.000 164.22647 ? 1092 GLU A H     1 
ATOM   4046 H  HA    . GLU A 1 309 ? -3.19827  60.11556  14.23573 1.000 164.20788 ? 1092 GLU A HA    1 
ATOM   4047 H  HB2   . GLU A 1 309 ? -4.37149  62.37101  14.05908 1.000 167.96530 ? 1092 GLU A HB2   1 
ATOM   4048 H  HB3   . GLU A 1 309 ? -3.02054  62.69825  13.28884 1.000 167.96530 ? 1092 GLU A HB3   1 
ATOM   4049 H  HG2   . GLU A 1 309 ? -4.57747  62.07241  11.73788 1.000 170.81390 ? 1092 GLU A HG2   1 
ATOM   4050 H  HG3   . GLU A 1 309 ? -3.49054  60.91586  11.81787 1.000 170.81390 ? 1092 GLU A HG3   1 
ATOM   4051 N  N     . GLN A 1 310 ? -0.62040  61.77469  14.99350 1.000 132.25322 ? 1093 GLN A N     1 
ATOM   4052 C  CA    . GLN A 1 310 ? 0.83069   61.74916  14.85674 1.000 129.73804 ? 1093 GLN A CA    1 
ATOM   4053 C  C     . GLN A 1 310 ? 1.36039   60.32473  14.96404 1.000 127.38405 ? 1093 GLN A C     1 
ATOM   4054 O  O     . GLN A 1 310 ? 2.42278   60.00963  14.41644 1.000 127.39794 ? 1093 GLN A O     1 
ATOM   4055 C  CB    . GLN A 1 310 ? 1.50967   62.61154  15.93182 1.000 129.29379 ? 1093 GLN A CB    1 
ATOM   4056 C  CG    . GLN A 1 310 ? 0.77447   63.87004  16.40935 1.000 132.71131 ? 1093 GLN A CG    1 
ATOM   4057 C  CD    . GLN A 1 310 ? 0.82814   65.01378  15.42067 1.000 135.05096 ? 1093 GLN A CD    1 
ATOM   4058 O  OE1   . GLN A 1 310 ? 1.11437   64.81794  14.24174 1.000 132.24373 ? 1093 GLN A OE1   1 
ATOM   4059 N  NE2   . GLN A 1 310 ? 0.55066   66.22131  15.89903 1.000 139.48357 ? 1093 GLN A NE2   1 
ATOM   4060 H  H     . GLN A 1 310 ? -0.91104  62.26445  15.63791 1.000 158.74707 ? 1093 GLN A H     1 
ATOM   4061 H  HA    . GLN A 1 310 ? 1.05402   62.12194  13.98952 1.000 155.72886 ? 1093 GLN A HA    1 
ATOM   4062 H  HB2   . GLN A 1 310 ? 1.64681   62.05514  16.71445 1.000 155.19576 ? 1093 GLN A HB2   1 
ATOM   4063 H  HB3   . GLN A 1 310 ? 2.36444   62.90502  15.57949 1.000 155.19576 ? 1093 GLN A HB3   1 
ATOM   4064 H  HG2   . GLN A 1 310 ? -0.15851  63.65006  16.55786 1.000 159.29678 ? 1093 GLN A HG2   1 
ATOM   4065 H  HG3   . GLN A 1 310 ? 1.17941   64.17407  17.23669 1.000 159.29678 ? 1093 GLN A HG3   1 
ATOM   4066 H  HE21  . GLN A 1 310 ? 0.35410   66.31971  16.73046 1.000 167.42350 ? 1093 GLN A HE21  1 
ATOM   4067 H  HE22  . GLN A 1 310 ? 0.56756   66.90480  15.37735 1.000 167.42350 ? 1093 GLN A HE22  1 
ATOM   4068 N  N     . LEU A 1 311 ? 0.63183   59.45635  15.67241 1.000 127.43649 ? 1094 LEU A N     1 
ATOM   4069 C  CA    . LEU A 1 311 ? 1.11144   58.10504  15.93815 1.000 126.74981 ? 1094 LEU A CA    1 
ATOM   4070 C  C     . LEU A 1 311 ? 1.30934   57.30754  14.65621 1.000 126.63970 ? 1094 LEU A C     1 
ATOM   4071 O  O     . LEU A 1 311 ? 2.12023   56.37449  14.62808 1.000 124.94105 ? 1094 LEU A O     1 
ATOM   4072 C  CB    . LEU A 1 311 ? 0.12953   57.38765  16.86685 1.000 125.54427 ? 1094 LEU A CB    1 
ATOM   4073 C  CG    . LEU A 1 311 ? -0.05516  58.02686  18.24568 1.000 124.71393 ? 1094 LEU A CG    1 
ATOM   4074 C  CD1   . LEU A 1 311 ? -1.22567  57.40456  18.98727 1.000 126.27624 ? 1094 LEU A CD1   1 
ATOM   4075 C  CD2   . LEU A 1 311 ? 1.21428   57.89566  19.06666 1.000 122.59826 ? 1094 LEU A CD2   1 
ATOM   4076 H  H     . LEU A 1 311 ? -0.14125  59.62702  16.00830 1.000 152.96701 ? 1094 LEU A H     1 
ATOM   4077 H  HA    . LEU A 1 311 ? 1.97192   58.15923  16.38260 1.000 152.14298 ? 1094 LEU A HA    1 
ATOM   4078 H  HB2   . LEU A 1 311 ? -0.73966  57.37006  16.43663 1.000 150.69634 ? 1094 LEU A HB2   1 
ATOM   4079 H  HB3   . LEU A 1 311 ? 0.44858   56.48244  17.00728 1.000 150.69634 ? 1094 LEU A HB3   1 
ATOM   4080 H  HG    . LEU A 1 311 ? -0.24806  58.96954  18.12302 1.000 149.69993 ? 1094 LEU A HG    1 
ATOM   4081 H  HD11  . LEU A 1 311 ? -1.27668  57.78913  19.87632 1.000 151.57471 ? 1094 LEU A HD11  1 
ATOM   4082 H  HD12  . LEU A 1 311 ? -2.04322  57.58994  18.49927 1.000 151.57471 ? 1094 LEU A HD12  1 
ATOM   4083 H  HD13  . LEU A 1 311 ? -1.08716  56.44647  19.04876 1.000 151.57471 ? 1094 LEU A HD13  1 
ATOM   4084 H  HD21  . LEU A 1 311 ? 1.10499   58.38427  19.89746 1.000 147.16113 ? 1094 LEU A HD21  1 
ATOM   4085 H  HD22  . LEU A 1 311 ? 1.37407   56.95731  19.25335 1.000 147.16113 ? 1094 LEU A HD22  1 
ATOM   4086 H  HD23  . LEU A 1 311 ? 1.95634   58.26351  18.56175 1.000 147.16113 ? 1094 LEU A HD23  1 
ATOM   4087 N  N     . LYS A 1 312 ? 0.58140   57.64888  13.59054 1.000 129.05685 ? 1095 LYS A N     1 
ATOM   4088 C  CA    . LYS A 1 312 ? 0.75417   56.93782  12.32771 1.000 125.61662 ? 1095 LYS A CA    1 
ATOM   4089 C  C     . LYS A 1 312 ? 2.19567   57.02825  11.84188 1.000 122.14972 ? 1095 LYS A C     1 
ATOM   4090 O  O     . LYS A 1 312 ? 2.74544   56.05286  11.31668 1.000 121.72612 ? 1095 LYS A O     1 
ATOM   4091 C  CB    . LYS A 1 312 ? -0.20313  57.49769  11.27601 1.000 120.93015 ? 1095 LYS A CB    1 
ATOM   4092 H  H     . LYS A 1 312 ? -0.00693  58.27594  13.57413 1.000 154.91144 ? 1095 LYS A H     1 
ATOM   4093 H  HA    . LYS A 1 312 ? 0.53821   56.00165  12.46132 1.000 150.78316 ? 1095 LYS A HA    1 
ATOM   4094 N  N     . THR A 1 313 ? 2.82397   58.19319  12.00984 1.000 122.83018 ? 1096 THR A N     1 
ATOM   4095 C  CA    . THR A 1 313 ? 4.22574   58.35043  11.63522 1.000 119.57025 ? 1096 THR A CA    1 
ATOM   4096 C  C     . THR A 1 313 ? 5.10743   57.38181  12.41463 1.000 117.45333 ? 1096 THR A C     1 
ATOM   4097 O  O     . THR A 1 313 ? 5.84223   56.57877  11.82859 1.000 117.75353 ? 1096 THR A O     1 
ATOM   4098 C  CB    . THR A 1 313 ? 4.66251   59.80148  11.86714 1.000 123.38595 ? 1096 THR A CB    1 
ATOM   4099 O  OG1   . THR A 1 313 ? 4.24800   60.60787  10.75583 1.000 121.15151 ? 1096 THR A OG1   1 
ATOM   4100 C  CG2   . THR A 1 313 ? 6.17875   59.91471  12.04618 1.000 121.24473 ? 1096 THR A CG2   1 
ATOM   4101 H  H     . THR A 1 313 ? 2.46252   58.90194  12.33638 1.000 147.43944 ? 1096 THR A H     1 
ATOM   4102 H  HA    . THR A 1 313 ? 4.32776   58.15331  10.69096 1.000 143.52752 ? 1096 THR A HA    1 
ATOM   4103 H  HB    . THR A 1 313 ? 4.24977   60.12729  12.68224 1.000 148.10636 ? 1096 THR A HB    1 
ATOM   4104 H  HG1   . THR A 1 313 ? 4.50982   61.39901  10.86145 1.000 145.42503 ? 1096 THR A HG1   1 
ATOM   4105 H  HG21  . THR A 1 313 ? 6.43534   60.84722  12.12030 1.000 145.53689 ? 1096 THR A HG21  1 
ATOM   4106 H  HG22  . THR A 1 313 ? 6.45361   59.44768  12.85069 1.000 145.53689 ? 1096 THR A HG22  1 
ATOM   4107 H  HG23  . THR A 1 313 ? 6.63300   59.52285  11.28395 1.000 145.53689 ? 1096 THR A HG23  1 
ATOM   4108 N  N     . THR A 1 314 ? 5.04719   57.44608  13.74738 1.000 115.24747 ? 1097 THR A N     1 
ATOM   4109 C  CA    . THR A 1 314 ? 5.86666   56.55724  14.56437 1.000 116.07532 ? 1097 THR A CA    1 
ATOM   4110 C  C     . THR A 1 314 ? 5.60622   55.09746  14.21557 1.000 116.89096 ? 1097 THR A C     1 
ATOM   4111 O  O     . THR A 1 314 ? 6.52657   54.27137  14.23624 1.000 114.40473 ? 1097 THR A O     1 
ATOM   4112 C  CB    . THR A 1 314 ? 5.59508   56.80483  16.04893 1.000 116.53871 ? 1097 THR A CB    1 
ATOM   4113 O  OG1   . THR A 1 314 ? 5.73437   58.20132  16.33817 1.000 117.64200 ? 1097 THR A OG1   1 
ATOM   4114 C  CG2   . THR A 1 314 ? 6.57022   56.01322  16.91381 1.000 121.23056 ? 1097 THR A CG2   1 
ATOM   4115 H  H     . THR A 1 314 ? 4.54838   57.98639  14.19331 1.000 138.34018 ? 1097 THR A H     1 
ATOM   4116 H  HA    . THR A 1 314 ? 6.80164   56.75045  14.39294 1.000 139.33360 ? 1097 THR A HA    1 
ATOM   4117 H  HB    . THR A 1 314 ? 4.69350   56.51751  16.26227 1.000 139.88967 ? 1097 THR A HB    1 
ATOM   4118 H  HG1   . THR A 1 314 ? 5.54165   58.34876  17.14236 1.000 141.21361 ? 1097 THR A HG1   1 
ATOM   4119 H  HG21  . THR A 1 314 ? 6.40940   56.20082  17.85181 1.000 145.51989 ? 1097 THR A HG21  1 
ATOM   4120 H  HG22  . THR A 1 314 ? 6.45504   55.06267  16.75863 1.000 145.51989 ? 1097 THR A HG22  1 
ATOM   4121 H  HG23  . THR A 1 314 ? 7.48267   56.25954  16.69546 1.000 145.51989 ? 1097 THR A HG23  1 
ATOM   4122 N  N     . ARG A 1 315 ? 4.35750   54.76058  13.88899 1.000 117.94728 ? 1098 ARG A N     1 
ATOM   4123 C  CA    . ARG A 1 315 ? 4.03276   53.38049  13.54397 1.000 114.03730 ? 1098 ARG A CA    1 
ATOM   4124 C  C     . ARG A 1 315 ? 4.72471   52.96030  12.25152 1.000 117.43605 ? 1098 ARG A C     1 
ATOM   4125 O  O     . ARG A 1 315 ? 5.34100   51.88955  12.18504 1.000 118.49084 ? 1098 ARG A O     1 
ATOM   4126 C  CB    . ARG A 1 315 ? 2.51658   53.21625  13.41882 1.000 114.31711 ? 1098 ARG A CB    1 
ATOM   4127 C  CG    . ARG A 1 315 ? 2.07410   51.79634  13.09330 1.000 115.31995 ? 1098 ARG A CG    1 
ATOM   4128 C  CD    . ARG A 1 315 ? 0.61699   51.74527  12.66519 1.000 117.51040 ? 1098 ARG A CD    1 
ATOM   4129 N  NE    . ARG A 1 315 ? 0.41527   52.34730  11.35245 1.000 122.51055 ? 1098 ARG A NE    1 
ATOM   4130 C  CZ    . ARG A 1 315 ? -0.72458  52.30804  10.67583 1.000 120.66174 ? 1098 ARG A CZ    1 
ATOM   4131 N  NH1   . ARG A 1 315 ? -1.79658  51.70310  11.16118 1.000 119.85912 ? 1098 ARG A NH1   1 
ATOM   4132 N  NH2   . ARG A 1 315 ? -0.78944  52.88754  9.48050  1.000 125.50320 ? 1098 ARG A NH2   1 
ATOM   4133 H  H     . ARG A 1 315 ? 3.69175   55.30423  13.86041 1.000 141.57995 ? 1098 ARG A H     1 
ATOM   4134 H  HA    . ARG A 1 315 ? 4.34312   52.79899  14.25561 1.000 136.88798 ? 1098 ARG A HA    1 
ATOM   4135 H  HB2   . ARG A 1 315 ? 2.10581   53.46801  14.26071 1.000 137.22375 ? 1098 ARG A HB2   1 
ATOM   4136 H  HB3   . ARG A 1 315 ? 2.19852   53.79500  12.70833 1.000 137.22375 ? 1098 ARG A HB3   1 
ATOM   4137 H  HG2   . ARG A 1 315 ? 2.61641   51.45020  12.36736 1.000 138.42715 ? 1098 ARG A HG2   1 
ATOM   4138 H  HG3   . ARG A 1 315 ? 2.17919   51.23954  13.88059 1.000 138.42715 ? 1098 ARG A HG3   1 
ATOM   4139 H  HD2   . ARG A 1 315 ? 0.32858   50.82012  12.62241 1.000 141.05570 ? 1098 ARG A HD2   1 
ATOM   4140 H  HD3   . ARG A 1 315 ? 0.07761   52.23152  13.30825 1.000 141.05570 ? 1098 ARG A HD3   1 
ATOM   4141 H  HE    . ARG A 1 315 ? 1.08100   52.75572  10.99244 1.000 147.05588 ? 1098 ARG A HE    1 
ATOM   4142 H  HH11  . ARG A 1 315 ? -1.76405  51.32356  11.93221 1.000 143.87416 ? 1098 ARG A HH11  1 
ATOM   4143 H  HH12  . ARG A 1 315 ? -2.52588  51.68946  10.70562 1.000 143.87416 ? 1098 ARG A HH12  1 
ATOM   4144 H  HH21  . ARG A 1 315 ? -0.09746  53.28139  9.15546  1.000 150.64705 ? 1098 ARG A HH21  1 
ATOM   4145 H  HH22  . ARG A 1 315 ? -1.52335  52.86842  9.03262  1.000 150.64705 ? 1098 ARG A HH22  1 
ATOM   4146 N  N     . ASN A 1 316 ? 4.63591   53.79444  11.21263 1.000 118.94195 ? 1099 ASN A N     1 
ATOM   4147 C  CA    . ASN A 1 316 ? 5.14174   53.40525  9.90002  1.000 117.67710 ? 1099 ASN A CA    1 
ATOM   4148 C  C     . ASN A 1 316 ? 6.66533   53.31853  9.87566  1.000 113.87980 ? 1099 ASN A C     1 
ATOM   4149 O  O     . ASN A 1 316 ? 7.22353   52.55440  9.07930  1.000 118.56580 ? 1099 ASN A O     1 
ATOM   4150 C  CB    . ASN A 1 316 ? 4.65894   54.39619  8.83924  1.000 119.75135 ? 1099 ASN A CB    1 
ATOM   4151 C  CG    . ASN A 1 316 ? 3.15715   54.36889  8.64601  1.000 115.91428 ? 1099 ASN A CG    1 
ATOM   4152 O  OD1   . ASN A 1 316 ? 2.48906   53.38888  8.97893  1.000 116.20594 ? 1099 ASN A OD1   1 
ATOM   4153 N  ND2   . ASN A 1 316 ? 2.61738   55.44900  8.09184  1.000 125.02348 ? 1099 ASN A ND2   1 
ATOM   4154 H  H     . ASN A 1 316 ? 4.29104   54.58170  11.24253 1.000 142.77355 ? 1099 ASN A H     1 
ATOM   4155 H  HA    . ASN A 1 316 ? 4.78945   52.52757  9.68445  1.000 141.25573 ? 1099 ASN A HA    1 
ATOM   4156 H  HB2   . ASN A 1 316 ? 4.90963   55.29366  9.10868  1.000 143.74483 ? 1099 ASN A HB2   1 
ATOM   4157 H  HB3   . ASN A 1 316 ? 5.07382   54.17656  7.99040  1.000 143.74483 ? 1099 ASN A HB3   1 
ATOM   4158 H  HD21  . ASN A 1 316 ? 1.76843   55.48571  7.95941  1.000 150.07139 ? 1099 ASN A HD21  1 
ATOM   4159 H  HD22  . ASN A 1 316 ? 3.11692   56.11145  7.86554  1.000 150.07139 ? 1099 ASN A HD22  1 
ATOM   4160 N  N     . ALA A 1 317 ? 7.34929   54.08312  10.74153 1.000 110.98810 ? 1100 ALA A N     1 
ATOM   4161 C  CA    . ALA A 1 317 ? 8.80797   54.15931  10.77889 1.000 110.44302 ? 1100 ALA A CA    1 
ATOM   4162 C  C     . ALA A 1 317 ? 9.44693   53.31403  11.87827 1.000 111.25772 ? 1100 ALA A C     1 
ATOM   4163 O  O     . ALA A 1 317 ? 10.65287  53.04575  11.80973 1.000 113.10754 ? 1100 ALA A O     1 
ATOM   4164 C  CB    . ALA A 1 317 ? 9.26373   55.61724  10.97358 1.000 114.89610 ? 1100 ALA A CB    1 
ATOM   4165 H  H     . ALA A 1 317 ? 6.97418   54.58088  11.33409 1.000 133.22894 ? 1100 ALA A H     1 
ATOM   4166 H  HA    . ALA A 1 317 ? 9.14137   53.84044  9.92562  1.000 132.57484 ? 1100 ALA A HA    1 
ATOM   4167 H  HB1   . ALA A 1 317 ? 10.19351  55.69554  10.70848 1.000 137.91854 ? 1100 ALA A HB1   1 
ATOM   4168 H  HB2   . ALA A 1 317 ? 8.71310   56.19635  10.42371 1.000 137.91854 ? 1100 ALA A HB2   1 
ATOM   4169 H  HB3   . ALA A 1 317 ? 9.16498   55.85684  11.90832 1.000 137.91854 ? 1100 ALA A HB3   1 
ATOM   4170 N  N     . TYR A 1 318 ? 8.68964   52.87981  12.87721 1.000 115.11365 ? 1101 TYR A N     1 
ATOM   4171 C  CA    . TYR A 1 318 ? 9.32953   52.24001  14.01545 1.000 111.51278 ? 1101 TYR A CA    1 
ATOM   4172 C  C     . TYR A 1 318 ? 8.57669   50.99224  14.44697 1.000 112.10916 ? 1101 TYR A C     1 
ATOM   4173 O  O     . TYR A 1 318 ? 9.19908   49.95054  14.67497 1.000 110.29870 ? 1101 TYR A O     1 
ATOM   4174 C  CB    . TYR A 1 318 ? 9.44926   53.22627  15.18131 1.000 115.29164 ? 1101 TYR A CB    1 
ATOM   4175 H  H     . TYR A 1 318 ? 7.83284   52.94211  12.91735 1.000 138.17960 ? 1101 TYR A H     1 
ATOM   4176 H  HA    . TYR A 1 318 ? 10.22292  51.96496  13.75640 1.000 133.85855 ? 1101 TYR A HA    1 
ATOM   4177 N  N     . ILE A 1 319 ? 7.24828   51.07218  14.55875 1.000 114.12559 ? 1102 ILE A N     1 
ATOM   4178 C  CA    . ILE A 1 319 ? 6.49415   49.93896  15.08834 1.000 112.91572 ? 1102 ILE A CA    1 
ATOM   4179 C  C     . ILE A 1 319 ? 6.27026   48.87967  14.00968 1.000 115.68704 ? 1102 ILE A C     1 
ATOM   4180 O  O     . ILE A 1 319 ? 6.08766   47.70063  14.33942 1.000 113.37383 ? 1102 ILE A O     1 
ATOM   4181 C  CB    . ILE A 1 319 ? 5.16506   50.41577  15.70990 1.000 113.33658 ? 1102 ILE A CB    1 
ATOM   4182 C  CG1   . ILE A 1 319 ? 5.37564   51.09323  17.07833 1.000 116.58176 ? 1102 ILE A CG1   1 
ATOM   4183 C  CG2   . ILE A 1 319 ? 4.17637   49.27372  15.87767 1.000 117.04807 ? 1102 ILE A CG2   1 
ATOM   4184 C  CD1   . ILE A 1 319 ? 6.42871   50.45395  17.96867 1.000 126.78194 ? 1102 ILE A CD1   1 
ATOM   4185 H  H     . ILE A 1 319 ? 6.77319   51.75486  14.34005 1.000 136.99392 ? 1102 ILE A H     1 
ATOM   4186 H  HA    . ILE A 1 319 ? 6.99799   49.51866  15.80276 1.000 135.54208 ? 1102 ILE A HA    1 
ATOM   4187 H  HB    . ILE A 1 319 ? 4.80456   51.06533  15.08620 1.000 136.04711 ? 1102 ILE A HB    1 
ATOM   4188 H  HG12  . ILE A 1 319 ? 5.64583   52.01225  16.92564 1.000 139.94133 ? 1102 ILE A HG12  1 
ATOM   4189 H  HG13  . ILE A 1 319 ? 4.53554   51.07054  17.56271 1.000 139.94133 ? 1102 ILE A HG13  1 
ATOM   4190 H  HG21  . ILE A 1 319 ? 3.33668   49.62902  16.20868 1.000 140.50089 ? 1102 ILE A HG21  1 
ATOM   4191 H  HG22  . ILE A 1 319 ? 4.03870   48.84634  15.01785 1.000 140.50089 ? 1102 ILE A HG22  1 
ATOM   4192 H  HG23  . ILE A 1 319 ? 4.53744   48.63391  16.51105 1.000 140.50089 ? 1102 ILE A HG23  1 
ATOM   4193 H  HD11  . ILE A 1 319 ? 6.36584   50.83736  18.85746 1.000 152.18154 ? 1102 ILE A HD11  1 
ATOM   4194 H  HD12  . ILE A 1 319 ? 6.27011   49.49785  18.00888 1.000 152.18154 ? 1102 ILE A HD12  1 
ATOM   4195 H  HD13  . ILE A 1 319 ? 7.30656   50.62819  17.59460 1.000 152.18154 ? 1102 ILE A HD13  1 
ATOM   4196 N  N     . GLN A 1 320 ? 6.28395   49.25628  12.72965 1.000 111.02905 ? 1103 GLN A N     1 
ATOM   4197 C  CA    . GLN A 1 320 ? 6.19377   48.25013  11.67469 1.000 112.42437 ? 1103 GLN A CA    1 
ATOM   4198 C  C     . GLN A 1 320 ? 7.50068   47.47686  11.54699 1.000 111.83539 ? 1103 GLN A C     1 
ATOM   4199 O  O     . GLN A 1 320 ? 7.49247   46.25028  11.38739 1.000 110.97069 ? 1103 GLN A O     1 
ATOM   4200 C  CB    . GLN A 1 320 ? 5.83181   48.90563  10.34252 1.000 115.02116 ? 1103 GLN A CB    1 
ATOM   4201 H  H     . GLN A 1 320 ? 6.34321   50.06831  12.45271 1.000 133.27807 ? 1103 GLN A H     1 
ATOM   4202 H  HA    . GLN A 1 320 ? 5.48660   47.62572  11.90034 1.000 134.95246 ? 1103 GLN A HA    1 
ATOM   4203 N  N     . LYS A 1 321 ? 8.63405   48.17946  11.61970 1.000 111.43092 ? 1104 LYS A N     1 
ATOM   4204 C  CA    . LYS A 1 321 ? 9.92859   47.51554  11.51478 1.000 106.88759 ? 1104 LYS A CA    1 
ATOM   4205 C  C     . LYS A 1 321 ? 10.14447  46.54445  12.66786 1.000 103.39388 ? 1104 LYS A C     1 
ATOM   4206 O  O     . LYS A 1 321 ? 10.71213  45.46194  12.47994 1.000 107.62079 ? 1104 LYS A O     1 
ATOM   4207 C  CB    . LYS A 1 321 ? 11.04674  48.55739  11.47612 1.000 103.88143 ? 1104 LYS A CB    1 
ATOM   4208 H  H     . LYS A 1 321 ? 8.67817   49.03144  11.72823 1.000 133.76032 ? 1104 LYS A H     1 
ATOM   4209 H  HA    . LYS A 1 321 ? 9.95636   47.01060  10.68703 1.000 128.30833 ? 1104 LYS A HA    1 
ATOM   4210 N  N     . TYR A 1 322 ? 9.70013   46.91262  13.87103 1.000 111.34509 ? 1105 TYR A N     1 
ATOM   4211 C  CA    . TYR A 1 322 ? 9.83377   46.01127  15.01072 1.000 110.08687 ? 1105 TYR A CA    1 
ATOM   4212 C  C     . TYR A 1 322 ? 8.97179   44.76799  14.82419 1.000 106.16433 ? 1105 TYR A C     1 
ATOM   4213 O  O     . TYR A 1 322 ? 9.43162   43.64236  15.04890 1.000 106.03586 ? 1105 TYR A O     1 
ATOM   4214 C  CB    . TYR A 1 322 ? 9.46192   46.73879  16.30340 1.000 111.11854 ? 1105 TYR A CB    1 
ATOM   4215 C  CG    . TYR A 1 322 ? 9.46999   45.85153  17.52992 1.000 116.96135 ? 1105 TYR A CG    1 
ATOM   4216 C  CD1   . TYR A 1 322 ? 10.59367  45.76392  18.34153 1.000 119.32954 ? 1105 TYR A CD1   1 
ATOM   4217 C  CD2   . TYR A 1 322 ? 8.35416   45.09848  17.87383 1.000 116.71121 ? 1105 TYR A CD2   1 
ATOM   4218 C  CE1   . TYR A 1 322 ? 10.60486  44.95618  19.46047 1.000 126.08029 ? 1105 TYR A CE1   1 
ATOM   4219 C  CE2   . TYR A 1 322 ? 8.35740   44.28618  18.99046 1.000 123.74983 ? 1105 TYR A CE2   1 
ATOM   4220 C  CZ    . TYR A 1 322 ? 9.48549   44.21949  19.77949 1.000 130.60495 ? 1105 TYR A CZ    1 
ATOM   4221 O  OH    . TYR A 1 322 ? 9.49654   43.41374  20.89289 1.000 143.62827 ? 1105 TYR A OH    1 
ATOM   4222 H  H     . TYR A 1 322 ? 9.32454   47.66546  14.04927 1.000 133.65733 ? 1105 TYR A H     1 
ATOM   4223 H  HA    . TYR A 1 322 ? 10.75944  45.73042  15.08259 1.000 132.14747 ? 1105 TYR A HA    1 
ATOM   4224 H  HB2   . TYR A 1 322 ? 10.09932  47.45466  16.45224 1.000 133.38546 ? 1105 TYR A HB2   1 
ATOM   4225 H  HB3   . TYR A 1 322 ? 8.56845   47.10444  16.20897 1.000 133.38546 ? 1105 TYR A HB3   1 
ATOM   4226 H  HD1   . TYR A 1 322 ? 11.35174  46.25819  18.12723 1.000 143.23867 ? 1105 TYR A HD1   1 
ATOM   4227 H  HD2   . TYR A 1 322 ? 7.59193   45.14227  17.34281 1.000 140.09667 ? 1105 TYR A HD2   1 
ATOM   4228 H  HE1   . TYR A 1 322 ? 11.36375  44.90949  19.99601 1.000 151.33956 ? 1105 TYR A HE1   1 
ATOM   4229 H  HE2   . TYR A 1 322 ? 7.60339   43.78741  19.20866 1.000 148.54301 ? 1105 TYR A HE2   1 
ATOM   4230 H  HH    . TYR A 1 322 ? 8.75442   43.02924  20.97665 1.000 172.39713 ? 1105 TYR A HH    1 
ATOM   4231 N  N     . LEU A 1 323 ? 7.71372   44.95274  14.41674 1.000 107.77515 ? 1106 LEU A N     1 
ATOM   4232 C  CA    . LEU A 1 323 ? 6.84065   43.80961  14.16815 1.000 108.67173 ? 1106 LEU A CA    1 
ATOM   4233 C  C     . LEU A 1 323 ? 7.47513   42.84671  13.17226 1.000 102.77687 ? 1106 LEU A C     1 
ATOM   4234 O  O     . LEU A 1 323 ? 7.50374   41.63120  13.39649 1.000 100.27222 ? 1106 LEU A O     1 
ATOM   4235 C  CB    . LEU A 1 323 ? 5.47985   44.29060  13.65880 1.000 106.68011 ? 1106 LEU A CB    1 
ATOM   4236 C  CG    . LEU A 1 323 ? 4.51209   43.21647  13.15045 1.000 104.76187 ? 1106 LEU A CG    1 
ATOM   4237 C  CD1   . LEU A 1 323 ? 4.00387   42.34972  14.29342 1.000 112.36920 ? 1106 LEU A CD1   1 
ATOM   4238 C  CD2   . LEU A 1 323 ? 3.34928   43.85037  12.39787 1.000 104.52622 ? 1106 LEU A CD2   1 
ATOM   4239 H  H     . LEU A 1 323 ? 7.34833   45.71902  14.27924 1.000 129.37340 ? 1106 LEU A H     1 
ATOM   4240 H  HA    . LEU A 1 323 ? 6.69984   43.33515  15.00239 1.000 130.44929 ? 1106 LEU A HA    1 
ATOM   4241 H  HB2   . LEU A 1 323 ? 5.03433   44.75224  14.38633 1.000 128.05935 ? 1106 LEU A HB2   1 
ATOM   4242 H  HB3   . LEU A 1 323 ? 5.63542   44.90322  12.92301 1.000 128.05935 ? 1106 LEU A HB3   1 
ATOM   4243 H  HG    . LEU A 1 323 ? 4.99009   42.63945  12.53445 1.000 125.75746 ? 1106 LEU A HG    1 
ATOM   4244 H  HD11  . LEU A 1 323 ? 3.42851   41.65704  13.93277 1.000 134.88626 ? 1106 LEU A HD11  1 
ATOM   4245 H  HD12  . LEU A 1 323 ? 4.76177   41.94773  14.74606 1.000 134.88626 ? 1106 LEU A HD12  1 
ATOM   4246 H  HD13  . LEU A 1 323 ? 3.50492   42.90480  14.91297 1.000 134.88626 ? 1106 LEU A HD13  1 
ATOM   4247 H  HD21  . LEU A 1 323 ? 2.80564   43.14835  12.00733 1.000 125.47468 ? 1106 LEU A HD21  1 
ATOM   4248 H  HD22  . LEU A 1 323 ? 2.81837   44.37293  13.01913 1.000 125.47468 ? 1106 LEU A HD22  1 
ATOM   4249 H  HD23  . LEU A 1 323 ? 3.70061   44.42409  11.69907 1.000 125.47468 ? 1106 LEU A HD23  1 
ATOM   4250 N  N     . GLU A 1 324 ? 7.99242   43.37567  12.06105 1.000 101.95107 ? 219  GLU A N     1 
ATOM   4251 C  CA    . GLU A 1 324 ? 8.55225   42.51283  11.02654 1.000 104.25333 ? 219  GLU A CA    1 
ATOM   4252 C  C     . GLU A 1 324 ? 9.81900   41.81618  11.50626 1.000 98.46021  ? 219  GLU A C     1 
ATOM   4253 O  O     . GLU A 1 324 ? 10.00364  40.61776  11.26337 1.000 100.02768 ? 219  GLU A O     1 
ATOM   4254 C  CB    . GLU A 1 324 ? 8.83597   43.32317  9.76264  1.000 101.87076 ? 219  GLU A CB    1 
ATOM   4255 C  CG    . GLU A 1 324 ? 7.60136   43.61237  8.92641  1.000 109.78789 ? 219  GLU A CG    1 
ATOM   4256 C  CD    . GLU A 1 324 ? 7.85962   43.47126  7.43762  1.000 114.84071 ? 219  GLU A CD    1 
ATOM   4257 O  OE1   . GLU A 1 324 ? 9.01347   43.68118  7.00694  1.000 119.64957 ? 219  GLU A OE1   1 
ATOM   4258 O  OE2   . GLU A 1 324 ? 6.90854   43.14054  6.69835  1.000 120.04363 ? 219  GLU A OE2   1 
ATOM   4259 H  H     . GLU A 1 324 ? 8.02996   44.21691  11.88638 1.000 122.38450 ? 219  GLU A H     1 
ATOM   4260 H  HA    . GLU A 1 324 ? 7.89877   41.83008  10.80811 1.000 125.14722 ? 219  GLU A HA    1 
ATOM   4261 H  HB2   . GLU A 1 324 ? 9.22494   44.17390  10.01924 1.000 122.28812 ? 219  GLU A HB2   1 
ATOM   4262 H  HB3   . GLU A 1 324 ? 9.45873   42.82733  9.20837  1.000 122.28812 ? 219  GLU A HB3   1 
ATOM   4263 H  HG2   . GLU A 1 324 ? 6.90016   42.98813  9.17042  1.000 131.78869 ? 219  GLU A HG2   1 
ATOM   4264 H  HG3   . GLU A 1 324 ? 7.30974   44.52180  9.09610  1.000 131.78869 ? 219  GLU A HG3   1 
ATOM   4265 N  N     . ARG A 1 325 ? 10.70676  42.54770  12.18231 1.000 97.73297  ? 220  ARG A N     1 
ATOM   4266 C  CA    . ARG A 1 325 ? 11.93462  41.93382  12.67520 1.000 97.72348  ? 220  ARG A CA    1 
ATOM   4267 C  C     . ARG A 1 325 ? 11.62948  40.83598  13.68577 1.000 97.87385  ? 220  ARG A C     1 
ATOM   4268 O  O     . ARG A 1 325 ? 12.23653  39.75907  13.64753 1.000 96.79808  ? 220  ARG A O     1 
ATOM   4269 C  CB    . ARG A 1 325 ? 12.84054  42.99691  13.29504 1.000 98.37135  ? 220  ARG A CB    1 
ATOM   4270 H  H     . ARG A 1 325 ? 10.62235  43.38395  12.36440 1.000 117.32278 ? 220  ARG A H     1 
ATOM   4271 H  HA    . ARG A 1 325 ? 12.40842  41.53498  11.92864 1.000 117.31139 ? 220  ARG A HA    1 
ATOM   4272 N  N     . ALA A 1 326 ? 10.68430  41.08628  14.59362 1.000 97.67472  ? 221  ALA A N     1 
ATOM   4273 C  CA    . ALA A 1 326 ? 10.34610  40.08693  15.60109 1.000 98.02005  ? 221  ALA A CA    1 
ATOM   4274 C  C     . ALA A 1 326 ? 9.70846   38.85965  14.96114 1.000 94.53867  ? 221  ALA A C     1 
ATOM   4275 O  O     . ALA A 1 326 ? 10.07862  37.72188  15.27316 1.000 96.59554  ? 221  ALA A O     1 
ATOM   4276 C  CB    . ALA A 1 326 ? 9.41724   40.69573  16.65122 1.000 101.82763 ? 221  ALA A CB    1 
ATOM   4277 H  H     . ALA A 1 326 ? 10.23201  41.81588  14.64575 1.000 117.25288 ? 221  ALA A H     1 
ATOM   4278 H  HA    . ALA A 1 326 ? 11.15893  39.80426  16.04864 1.000 117.66727 ? 221  ALA A HA    1 
ATOM   4279 H  HB1   . ALA A 1 326 ? 9.23294   40.03103  17.33320 1.000 122.23638 ? 221  ALA A HB1   1 
ATOM   4280 H  HB2   . ALA A 1 326 ? 9.85227   41.46603  17.04909 1.000 122.23638 ? 221  ALA A HB2   1 
ATOM   4281 H  HB3   . ALA A 1 326 ? 8.59077   40.96751  16.22228 1.000 122.23638 ? 221  ALA A HB3   1 
ATOM   4282 N  N     . ARG A 1 327 ? 8.74381   39.06949  14.06215 1.000 94.21405  ? 222  ARG A N     1 
ATOM   4283 C  CA    . ARG A 1 327 ? 8.14191   37.94171  13.35933 1.000 94.20120  ? 222  ARG A CA    1 
ATOM   4284 C  C     . ARG A 1 327 ? 9.20289   37.13169  12.62668 1.000 94.85267  ? 222  ARG A C     1 
ATOM   4285 O  O     . ARG A 1 327 ? 9.15575   35.89615  12.61400 1.000 97.27094  ? 222  ARG A O     1 
ATOM   4286 C  CB    . ARG A 1 327 ? 7.07587   38.43816  12.38255 1.000 90.53128  ? 222  ARG A CB    1 
ATOM   4287 H  H     . ARG A 1 327 ? 8.42777   39.83975  13.84670 1.000 113.10007 ? 222  ARG A H     1 
ATOM   4288 H  HA    . ARG A 1 327 ? 7.70725   37.36269  14.00486 1.000 113.08465 ? 222  ARG A HA    1 
ATOM   4289 N  N     . SER A 1 328 ? 10.17708  37.81332  12.01967 1.000 92.47024  ? 223  SER A N     1 
ATOM   4290 C  CA    . SER A 1 328 ? 11.23852  37.10961  11.30869 1.000 96.12287  ? 223  SER A CA    1 
ATOM   4291 C  C     . SER A 1 328 ? 12.06575  36.25593  12.26173 1.000 92.78933  ? 223  SER A C     1 
ATOM   4292 O  O     . SER A 1 328 ? 12.37905  35.09755  11.95914 1.000 91.42508  ? 223  SER A O     1 
ATOM   4293 C  CB    . SER A 1 328 ? 12.12944  38.11661  10.57980 1.000 95.02596  ? 223  SER A CB    1 
ATOM   4294 O  OG    . SER A 1 328 ? 13.25514  37.47700  10.00551 1.000 103.02424 ? 223  SER A OG    1 
ATOM   4295 H  H     . SER A 1 328 ? 10.24382  38.67061  12.00589 1.000 111.00751 ? 223  SER A H     1 
ATOM   4296 H  HA    . SER A 1 328 ? 10.84073  36.52193  10.64741 1.000 115.39066 ? 223  SER A HA    1 
ATOM   4297 H  HB2   . SER A 1 328 ? 11.61467  38.54062  9.87544  1.000 114.07437 ? 223  SER A HB2   1 
ATOM   4298 H  HB3   . SER A 1 328 ? 12.43563  38.78338  11.21428 1.000 114.07437 ? 223  SER A HB3   1 
ATOM   4299 H  HG    . SER A 1 328 ? 13.75850  38.04703  9.64874  1.000 123.67230 ? 223  SER A HG    1 
ATOM   4300 N  N     . THR A 1 329 ? 12.42584  36.80851  13.42076 1.000 89.37506  ? 224  THR A N     1 
ATOM   4301 C  CA    . THR A 1 329 ? 13.25470  36.06624  14.36366 1.000 90.15411  ? 224  THR A CA    1 
ATOM   4302 C  C     . THR A 1 329 ? 12.52439  34.83742  14.89222 1.000 91.05038  ? 224  THR A C     1 
ATOM   4303 O  O     . THR A 1 329 ? 13.13324  33.77774  15.08294 1.000 89.54743  ? 224  THR A O     1 
ATOM   4304 C  CB    . THR A 1 329 ? 13.67245  36.97191  15.52151 1.000 91.28001  ? 224  THR A CB    1 
ATOM   4305 O  OG1   . THR A 1 329 ? 13.98070  38.27881  15.02260 1.000 95.84664  ? 224  THR A OG1   1 
ATOM   4306 C  CG2   . THR A 1 329 ? 14.89631  36.40723  16.22423 1.000 87.30517  ? 224  THR A CG2   1 
ATOM   4307 H  H     . THR A 1 329 ? 12.20652  37.59871  13.67977 1.000 107.29328 ? 224  THR A H     1 
ATOM   4308 H  HA    . THR A 1 329 ? 14.05648  35.76963  13.90532 1.000 108.22815 ? 224  THR A HA    1 
ATOM   4309 H  HB    . THR A 1 329 ? 12.94685  37.03061  16.16256 1.000 109.57923 ? 224  THR A HB    1 
ATOM   4310 H  HG1   . THR A 1 329 ? 14.18582  38.78804  15.65838 1.000 115.05918 ? 224  THR A HG1   1 
ATOM   4311 H  HG21  . THR A 1 329 ? 15.14882  36.98183  16.96380 1.000 104.80942 ? 224  THR A HG21  1 
ATOM   4312 H  HG22  . THR A 1 329 ? 14.70273  35.52047  16.56640 1.000 104.80942 ? 224  THR A HG22  1 
ATOM   4313 H  HG23  . THR A 1 329 ? 15.63871  36.34965  15.60260 1.000 104.80942 ? 224  THR A HG23  1 
ATOM   4314 N  N     . LEU A 1 330 ? 11.21839  34.95905  15.14074 1.000 93.53508  ? 225  LEU A N     1 
ATOM   4315 C  CA    . LEU A 1 330 ? 10.46062  33.81722  15.64193 1.000 94.51368  ? 225  LEU A CA    1 
ATOM   4316 C  C     . LEU A 1 330 ? 10.29132  32.75572  14.56226 1.000 91.91457  ? 225  LEU A C     1 
ATOM   4317 O  O     . LEU A 1 330 ? 10.39209  31.55590  14.84417 1.000 89.62744  ? 225  LEU A O     1 
ATOM   4318 C  CB    . LEU A 1 330 ? 9.10331   34.27847  16.17201 1.000 93.88295  ? 225  LEU A CB    1 
ATOM   4319 C  CG    . LEU A 1 330 ? 9.13318   34.92598  17.55941 1.000 97.04523  ? 225  LEU A CG    1 
ATOM   4320 C  CD1   . LEU A 1 330 ? 7.78460   35.53592  17.91157 1.000 101.39354 ? 225  LEU A CD1   1 
ATOM   4321 C  CD2   . LEU A 1 330 ? 9.54580   33.91140  18.61968 1.000 91.13680  ? 225  LEU A CD2   1 
ATOM   4322 H  H     . LEU A 1 330 ? 10.75858  35.67722  15.02939 1.000 112.28531 ? 225  LEU A H     1 
ATOM   4323 H  HA    . LEU A 1 330 ? 10.94473  33.41701  16.38109 1.000 113.45963 ? 225  LEU A HA    1 
ATOM   4324 H  HB2   . LEU A 1 330 ? 8.73943   34.93149  15.55391 1.000 112.70275 ? 225  LEU A HB2   1 
ATOM   4325 H  HB3   . LEU A 1 330 ? 8.51694   33.50747  16.22330 1.000 112.70275 ? 225  LEU A HB3   1 
ATOM   4326 H  HG    . LEU A 1 330 ? 9.78930   35.64030  17.54725 1.000 116.49749 ? 225  LEU A HG    1 
ATOM   4327 H  HD11  . LEU A 1 330 ? 7.87296   36.04505  18.73247 1.000 121.71546 ? 225  LEU A HD11  1 
ATOM   4328 H  HD12  . LEU A 1 330 ? 7.50348   36.11914  17.18926 1.000 121.71546 ? 225  LEU A HD12  1 
ATOM   4329 H  HD13  . LEU A 1 330 ? 7.13758   34.82340  18.03228 1.000 121.71546 ? 225  LEU A HD13  1 
ATOM   4330 H  HD21  . LEU A 1 330 ? 9.39539   34.29392  19.49829 1.000 109.40737 ? 225  LEU A HD21  1 
ATOM   4331 H  HD22  . LEU A 1 330 ? 9.01239   33.10831  18.51282 1.000 109.40737 ? 225  LEU A HD22  1 
ATOM   4332 H  HD23  . LEU A 1 330 ? 10.48606  33.70142  18.50687 1.000 109.40737 ? 225  LEU A HD23  1 
ATOM   4333 N  N     . GLN A 1 331 ? 10.03684  33.17431  13.31993 1.000 93.09621  ? 226  GLN A N     1 
ATOM   4334 C  CA    . GLN A 1 331 ? 10.00405  32.21623  12.21987 1.000 85.99826  ? 226  GLN A CA    1 
ATOM   4335 C  C     . GLN A 1 331 ? 11.33251  31.47966  12.10880 1.000 88.87264  ? 226  GLN A C     1 
ATOM   4336 O  O     . GLN A 1 331 ? 11.36803  30.28298  11.79805 1.000 89.92608  ? 226  GLN A O     1 
ATOM   4337 C  CB    . GLN A 1 331 ? 9.67376   32.93123  10.90979 1.000 84.87549  ? 226  GLN A CB    1 
ATOM   4338 H  H     . GLN A 1 331 ? 9.88344   33.98987  13.09424 1.000 111.75866 ? 226  GLN A H     1 
ATOM   4339 H  HA    . GLN A 1 331 ? 9.30522   31.56434  12.38598 1.000 103.24113 ? 226  GLN A HA    1 
ATOM   4340 N  N     . LYS A 1 332 ? 12.43725  32.18104  12.36861 1.000 87.99382  ? 227  LYS A N     1 
ATOM   4341 C  CA    . LYS A 1 332 ? 13.74866  31.54319  12.35085 1.000 86.19455  ? 227  LYS A CA    1 
ATOM   4342 C  C     . LYS A 1 332 ? 13.86299  30.49678  13.45210 1.000 86.00556  ? 227  LYS A C     1 
ATOM   4343 O  O     . LYS A 1 332 ? 14.31405  29.37092  13.21133 1.000 84.99785  ? 227  LYS A O     1 
ATOM   4344 C  CB    . LYS A 1 332 ? 14.83975  32.60330  12.50150 1.000 84.95500  ? 227  LYS A CB    1 
ATOM   4345 C  CG    . LYS A 1 332 ? 15.56188  32.95451  11.20916 1.000 83.92287  ? 227  LYS A CG    1 
ATOM   4346 C  CD    . LYS A 1 332 ? 16.35699  34.25908  11.32207 1.000 87.41591  ? 227  LYS A CD    1 
ATOM   4347 C  CE    . LYS A 1 332 ? 16.81301  34.54492  12.75107 1.000 89.74081  ? 227  LYS A CE    1 
ATOM   4348 N  NZ    . LYS A 1 332 ? 17.91179  35.55191  12.81877 1.000 93.40937  ? 227  LYS A NZ    1 
ATOM   4349 H  H     . LYS A 1 332 ? 12.45281  33.02018  12.55623 1.000 105.63580 ? 227  LYS A H     1 
ATOM   4350 H  HA    . LYS A 1 332 ? 13.87149  31.09733  11.49819 1.000 103.47667 ? 227  LYS A HA    1 
ATOM   4351 H  HB2   . LYS A 1 332 ? 14.43513  33.41678  12.84126 1.000 101.98922 ? 227  LYS A HB2   1 
ATOM   4352 H  HB3   . LYS A 1 332 ? 15.50374  32.27614  13.12839 1.000 101.98922 ? 227  LYS A HB3   1 
ATOM   4353 H  HG2   . LYS A 1 332 ? 16.18178  32.24213  10.98749 1.000 100.75067 ? 227  LYS A HG2   1 
ATOM   4354 H  HG3   . LYS A 1 332 ? 14.90970  33.05974  10.49888 1.000 100.75067 ? 227  LYS A HG3   1 
ATOM   4355 H  HD2   . LYS A 1 332 ? 17.14612  34.19929  10.76117 1.000 104.94231 ? 227  LYS A HD2   1 
ATOM   4356 H  HD3   . LYS A 1 332 ? 15.79863  34.99715  11.03158 1.000 104.94231 ? 227  LYS A HD3   1 
ATOM   4357 H  HE2   . LYS A 1 332 ? 16.06153  34.88738  13.25989 1.000 107.73219 ? 227  LYS A HE2   1 
ATOM   4358 H  HE3   . LYS A 1 332 ? 17.13633  33.72199  13.15002 1.000 107.73219 ? 227  LYS A HE3   1 
ATOM   4359 H  HZ1   . LYS A 1 332 ? 18.11144  35.72797  13.66803 1.000 112.13446 ? 227  LYS A HZ1   1 
ATOM   4360 H  HZ2   . LYS A 1 332 ? 18.63773  35.23825  12.41045 1.000 112.13446 ? 227  LYS A HZ2   1 
ATOM   4361 H  HZ3   . LYS A 1 332 ? 17.65874  36.30588  12.41927 1.000 112.13446 ? 227  LYS A HZ3   1 
ATOM   4362 N  N     . GLU A 1 333 ? 13.46736  30.85571  14.67615 1.000 88.04335  ? 228  GLU A N     1 
ATOM   4363 C  CA    . GLU A 1 333 ? 13.51049  29.89482  15.77371 1.000 83.69299  ? 228  GLU A CA    1 
ATOM   4364 C  C     . GLU A 1 333 ? 12.66077  28.66981  15.45993 1.000 79.96509  ? 228  GLU A C     1 
ATOM   4365 O  O     . GLU A 1 333 ? 13.05458  27.53704  15.76039 1.000 76.51813  ? 228  GLU A O     1 
ATOM   4366 C  CB    . GLU A 1 333 ? 13.04121  30.55705  17.06931 1.000 84.85072  ? 228  GLU A CB    1 
ATOM   4367 H  H     . GLU A 1 333 ? 13.17544  31.63539  14.89174 1.000 105.69523 ? 228  GLU A H     1 
ATOM   4368 H  HA    . GLU A 1 333 ? 14.42672  29.60326  15.90187 1.000 100.47480 ? 228  GLU A HA    1 
ATOM   4369 N  N     . VAL A 1 334 ? 11.49059  28.87717  14.85266 1.000 81.62664  ? 229  VAL A N     1 
ATOM   4370 C  CA    . VAL A 1 334 ? 10.65766  27.75060  14.44220 1.000 83.08009  ? 229  VAL A CA    1 
ATOM   4371 C  C     . VAL A 1 334 ? 11.40537  26.87574  13.44437 1.000 78.32496  ? 229  VAL A C     1 
ATOM   4372 O  O     . VAL A 1 334 ? 11.39435  25.64279  13.54764 1.000 72.60090  ? 229  VAL A O     1 
ATOM   4373 C  CB    . VAL A 1 334 ? 9.32249   28.26148  13.86724 1.000 85.75714  ? 229  VAL A CB    1 
ATOM   4374 C  CG1   . VAL A 1 334 ? 8.63584   27.18497  13.03294 1.000 83.35001  ? 229  VAL A CG1   1 
ATOM   4375 C  CG2   . VAL A 1 334 ? 8.40913   28.72293  14.99389 1.000 78.43489  ? 229  VAL A CG2   1 
ATOM   4376 H  H     . VAL A 1 334 ? 11.16160  29.65041  14.66969 1.000 97.99519  ? 229  VAL A H     1 
ATOM   4377 H  HA    . VAL A 1 334 ? 10.45942  27.20808  15.22148 1.000 99.73932  ? 229  VAL A HA    1 
ATOM   4378 H  HB    . VAL A 1 334 ? 9.50459   29.01543  13.28475 1.000 102.95178 ? 229  VAL A HB    1 
ATOM   4379 H  HG11  . VAL A 1 334 ? 7.73733   27.47894  12.81578 1.000 100.06323 ? 229  VAL A HG11  1 
ATOM   4380 H  HG12  . VAL A 1 334 ? 9.14383   27.04462  12.21860 1.000 100.06323 ? 229  VAL A HG12  1 
ATOM   4381 H  HG13  . VAL A 1 334 ? 8.59985   26.36269  13.54621 1.000 100.06323 ? 229  VAL A HG13  1 
ATOM   4382 H  HG21  . VAL A 1 334 ? 7.58344   29.06051  14.61287 1.000 94.16509  ? 229  VAL A HG21  1 
ATOM   4383 H  HG22  . VAL A 1 334 ? 8.22126   27.97042  15.57642 1.000 94.16509  ? 229  VAL A HG22  1 
ATOM   4384 H  HG23  . VAL A 1 334 ? 8.85416   29.42510  15.49370 1.000 94.16509  ? 229  VAL A HG23  1 
ATOM   4385 N  N     . HIS A 1 335 ? 12.06915  27.49654  12.46522 1.000 80.52451  ? 230  HIS A N     1 
ATOM   4386 C  CA    . HIS A 1 335 ? 12.81821  26.72970  11.47320 1.000 78.19805  ? 230  HIS A CA    1 
ATOM   4387 C  C     . HIS A 1 335 ? 13.91087  25.89892  12.13650 1.000 78.59991  ? 230  HIS A C     1 
ATOM   4388 O  O     . HIS A 1 335 ? 14.06797  24.70759  11.84266 1.000 78.72421  ? 230  HIS A O     1 
ATOM   4389 C  CB    . HIS A 1 335 ? 13.41832  27.67255  10.42670 1.000 79.17557  ? 230  HIS A CB    1 
ATOM   4390 C  CG    . HIS A 1 335 ? 14.22471  26.97644  9.37195  1.000 81.81112  ? 230  HIS A CG    1 
ATOM   4391 N  ND1   . HIS A 1 335 ? 13.77336  26.80545  8.08070  1.000 84.52297  ? 230  HIS A ND1   1 
ATOM   4392 C  CD2   . HIS A 1 335 ? 15.45407  26.40928  9.41777  1.000 80.64213  ? 230  HIS A CD2   1 
ATOM   4393 C  CE1   . HIS A 1 335 ? 14.68940  26.16399  7.37691  1.000 82.22605  ? 230  HIS A CE1   1 
ATOM   4394 N  NE2   . HIS A 1 335 ? 15.71839  25.91032  8.16530  1.000 77.06781  ? 230  HIS A NE2   1 
ATOM   4395 H  H     . HIS A 1 335 ? 12.10033  28.34900  12.35587 1.000 96.67262  ? 230  HIS A H     1 
ATOM   4396 H  HA    . HIS A 1 335 ? 12.21035  26.12431  11.02054 1.000 93.88088  ? 230  HIS A HA    1 
ATOM   4397 H  HB2   . HIS A 1 335 ? 12.69650  28.14470  9.98291  1.000 95.05390  ? 230  HIS A HB2   1 
ATOM   4398 H  HB3   . HIS A 1 335 ? 14.00169  28.30448  10.87531 1.000 95.05390  ? 230  HIS A HB3   1 
ATOM   4399 H  HD2   . HIS A 1 335 ? 16.01447  26.36578  10.15869 1.000 96.81377  ? 230  HIS A HD2   1 
ATOM   4400 H  HE1   . HIS A 1 335 ? 14.62125  25.93078  6.47921  1.000 98.71448  ? 230  HIS A HE1   1 
ATOM   4401 H  HE2   . HIS A 1 335 ? 16.43714  25.49952  7.93240  1.000 92.52459  ? 230  HIS A HE2   1 
ATOM   4402 N  N     . ALA A 1 336 ? 14.68285  26.51617  13.03480 1.000 75.12689  ? 231  ALA A N     1 
ATOM   4403 C  CA    . ALA A 1 336 ? 15.74799  25.78797  13.71625 1.000 70.63078  ? 231  ALA A CA    1 
ATOM   4404 C  C     . ALA A 1 336 ? 15.18825  24.65213  14.56330 1.000 73.57605  ? 231  ALA A C     1 
ATOM   4405 O  O     . ALA A 1 336 ? 15.76918  23.56132  14.61483 1.000 73.24680  ? 231  ALA A O     1 
ATOM   4406 C  CB    . ALA A 1 336 ? 16.56393  26.74478  14.58331 1.000 73.70415  ? 231  ALA A CB    1 
ATOM   4407 H  H     . ALA A 1 336 ? 14.61025  27.34227  13.26259 1.000 90.19548  ? 231  ALA A H     1 
ATOM   4408 H  HA    . ALA A 1 336 ? 16.33816  25.40411  13.04899 1.000 84.80016  ? 231  ALA A HA    1 
ATOM   4409 H  HB1   . ALA A 1 336 ? 17.27415  26.24828  15.01918 1.000 88.48820  ? 231  ALA A HB1   1 
ATOM   4410 H  HB2   . ALA A 1 336 ? 16.94242  27.43727  14.01929 1.000 88.48820  ? 231  ALA A HB2   1 
ATOM   4411 H  HB3   . ALA A 1 336 ? 15.98134  27.14227  15.24926 1.000 88.48820  ? 231  ALA A HB3   1 
ATOM   4412 N  N     . ALA A 1 337 ? 14.06623  24.89209  15.24649 1.000 75.17309  ? 232  ALA A N     1 
ATOM   4413 C  CA    . ALA A 1 337 ? 13.44926  23.83483  16.04059 1.000 73.21467  ? 232  ALA A CA    1 
ATOM   4414 C  C     . ALA A 1 337 ? 12.94387  22.70669  15.15018 1.000 73.34368  ? 232  ALA A C     1 
ATOM   4415 O  O     . ALA A 1 337 ? 13.03949  21.52875  15.51549 1.000 70.51672  ? 232  ALA A O     1 
ATOM   4416 C  CB    . ALA A 1 337 ? 12.30774  24.40592  16.88107 1.000 73.99886  ? 232  ALA A CB    1 
ATOM   4417 H  H     . ALA A 1 337 ? 13.65130  25.64513  15.26539 1.000 90.25092  ? 232  ALA A H     1 
ATOM   4418 H  HA    . ALA A 1 337 ? 14.11298  23.46993  16.64658 1.000 87.90082  ? 232  ALA A HA    1 
ATOM   4419 H  HB1   . ALA A 1 337 ? 11.91753  23.69258  17.41003 1.000 88.84185  ? 232  ALA A HB1   1 
ATOM   4420 H  HB2   . ALA A 1 337 ? 12.65994  25.09591  17.46482 1.000 88.84185  ? 232  ALA A HB2   1 
ATOM   4421 H  HB3   . ALA A 1 337 ? 11.63810  24.78329  16.28940 1.000 88.84185  ? 232  ALA A HB3   1 
ATOM   4422 N  N     . LYS A 1 338 ? 12.40450  23.04670  13.97717 1.000 73.62384  ? 233  LYS A N     1 
ATOM   4423 C  CA    . LYS A 1 338 ? 11.94552  22.01509  13.05369 1.000 73.88085  ? 233  LYS A CA    1 
ATOM   4424 C  C     . LYS A 1 338 ? 13.10737  21.15131  12.58117 1.000 71.13886  ? 233  LYS A C     1 
ATOM   4425 O  O     . LYS A 1 338 ? 12.97548  19.92717  12.46553 1.000 69.88314  ? 233  LYS A O     1 
ATOM   4426 C  CB    . LYS A 1 338 ? 11.23431  22.65563  11.86183 1.000 75.85875  ? 233  LYS A CB    1 
ATOM   4427 H  H     . LYS A 1 338 ? 12.29578  23.85317  13.69899 1.000 88.39182  ? 233  LYS A H     1 
ATOM   4428 H  HA    . LYS A 1 338 ? 11.30819  21.44417  13.51059 1.000 88.70023  ? 233  LYS A HA    1 
ATOM   4429 N  N     . SER A 1 339 ? 14.25534  21.77166  12.30332 1.000 71.88223  ? 234  SER A N     1 
ATOM   4430 C  CA    . SER A 1 339 ? 15.43129  21.00644  11.90448 1.000 73.36711  ? 234  SER A CA    1 
ATOM   4431 C  C     . SER A 1 339 ? 15.84957  20.03977  13.00503 1.000 67.22380  ? 234  SER A C     1 
ATOM   4432 O  O     . SER A 1 339 ? 16.13902  18.86661  12.74318 1.000 67.31255  ? 234  SER A O     1 
ATOM   4433 C  CB    . SER A 1 339 ? 16.57971  21.95520  11.56089 1.000 74.57274  ? 234  SER A CB    1 
ATOM   4434 O  OG    . SER A 1 339 ? 16.20252  22.86478  10.54377 1.000 74.91580  ? 234  SER A OG    1 
ATOM   4435 H  H     . SER A 1 339 ? 14.37625  22.62241  12.33810 1.000 86.30190  ? 234  SER A H     1 
ATOM   4436 H  HA    . SER A 1 339 ? 15.21647  20.49110  11.11128 1.000 88.08375  ? 234  SER A HA    1 
ATOM   4437 H  HB2   . SER A 1 339 ? 16.82341  22.45513  12.35561 1.000 89.53051  ? 234  SER A HB2   1 
ATOM   4438 H  HB3   . SER A 1 339 ? 17.33697  21.43375  11.25178 1.000 89.53051  ? 234  SER A HB3   1 
ATOM   4439 H  HG    . SER A 1 339 ? 16.84536  23.37343  10.36038 1.000 89.94218  ? 234  SER A HG    1 
ATOM   4440 N  N     . ALA A 1 340 ? 15.89253  20.52052  14.24887 1.000 65.11731  ? 235  ALA A N     1 
ATOM   4441 C  CA    . ALA A 1 340 ? 16.27250  19.65688  15.36096 1.000 64.74152  ? 235  ALA A CA    1 
ATOM   4442 C  C     . ALA A 1 340 ? 15.26622  18.52947  15.55324 1.000 59.99035  ? 235  ALA A C     1 
ATOM   4443 O  O     . ALA A 1 340 ? 15.64728  17.39006  15.84540 1.000 59.54722  ? 235  ALA A O     1 
ATOM   4444 C  CB    . ALA A 1 340 ? 16.40234  20.48202  16.64066 1.000 72.15245  ? 235  ALA A CB    1 
ATOM   4445 H  H     . ALA A 1 340 ? 15.70885  21.33087  14.47067 1.000 78.18398  ? 235  ALA A H     1 
ATOM   4446 H  HA    . ALA A 1 340 ? 17.13590  19.25914  15.16798 1.000 77.73304  ? 235  ALA A HA    1 
ATOM   4447 H  HB1   . ALA A 1 340 ? 16.67794  19.89934  17.36552 1.000 86.62616  ? 235  ALA A HB1   1 
ATOM   4448 H  HB2   . ALA A 1 340 ? 17.06630  21.17567  16.50316 1.000 86.62616  ? 235  ALA A HB2   1 
ATOM   4449 H  HB3   . ALA A 1 340 ? 15.54327  20.88260  16.84665 1.000 86.62616  ? 235  ALA A HB3   1 
ATOM   4450 N  N     . ALA A 1 341 ? 13.97397  18.82905  15.40145 1.000 61.76315  ? 236  ALA A N     1 
ATOM   4451 C  CA    . ALA A 1 341 ? 12.95582  17.79369  15.54041 1.000 61.74003  ? 236  ALA A CA    1 
ATOM   4452 C  C     . ALA A 1 341 ? 13.04534  16.76804  14.41792 1.000 60.97463  ? 236  ALA A C     1 
ATOM   4453 O  O     . ALA A 1 341 ? 12.74950  15.58657  14.63421 1.000 58.48440  ? 236  ALA A O     1 
ATOM   4454 C  CB    . ALA A 1 341 ? 11.56486  18.42723  15.57057 1.000 63.01011  ? 236  ALA A CB    1 
ATOM   4455 H  H     . ALA A 1 341 ? 13.66736  19.61193  15.22070 1.000 74.15900  ? 236  ALA A H     1 
ATOM   4456 H  HA    . ALA A 1 341 ? 13.09255  17.33107  16.38194 1.000 74.13125  ? 236  ALA A HA    1 
ATOM   4457 H  HB1   . ALA A 1 341 ? 10.90142  17.72759  15.67664 1.000 75.65534  ? 236  ALA A HB1   1 
ATOM   4458 H  HB2   . ALA A 1 341 ? 11.51560  19.04560  16.31629 1.000 75.65534  ? 236  ALA A HB2   1 
ATOM   4459 H  HB3   . ALA A 1 341 ? 11.41555  18.90112  14.73748 1.000 75.65534  ? 236  ALA A HB3   1 
ATOM   4460 N  N     . ILE A 1 342 ? 13.44527  17.19881  13.21830 1.000 63.71993  ? 237  ILE A N     1 
ATOM   4461 C  CA    . ILE A 1 342 ? 13.63202  16.26357  12.11235 1.000 63.03775  ? 237  ILE A CA    1 
ATOM   4462 C  C     . ILE A 1 342 ? 14.70409  15.24309  12.46323 1.000 61.66077  ? 237  ILE A C     1 
ATOM   4463 O  O     . ILE A 1 342 ? 14.53968  14.03827  12.22982 1.000 60.32407  ? 237  ILE A O     1 
ATOM   4464 C  CB    . ILE A 1 342 ? 13.97725  17.03438  10.82137 1.000 69.77246  ? 237  ILE A CB    1 
ATOM   4465 C  CG1   . ILE A 1 342 ? 12.69567  17.54334  10.15571 1.000 66.27985  ? 237  ILE A CG1   1 
ATOM   4466 C  CG2   . ILE A 1 342 ? 14.76401  16.15873  9.84587  1.000 67.37206  ? 237  ILE A CG2   1 
ATOM   4467 C  CD1   . ILE A 1 342 ? 12.83032  18.90187  9.50563  1.000 71.44252  ? 237  ILE A CD1   1 
ATOM   4468 H  H     . ILE A 1 342 ? 13.61302  18.01922  13.02238 1.000 76.50714  ? 237  ILE A H     1 
ATOM   4469 H  HA    . ILE A 1 342 ? 12.80219  15.78429  11.96209 1.000 75.68851  ? 237  ILE A HA    1 
ATOM   4470 H  HB    . ILE A 1 342 ? 14.53421  17.79012  11.06539 1.000 83.77017  ? 237  ILE A HB    1 
ATOM   4471 H  HG12  . ILE A 1 342 ? 12.43268  16.91282  9.46710  1.000 79.57904  ? 237  ILE A HG12  1 
ATOM   4472 H  HG13  . ILE A 1 342 ? 12.00092  17.60757  10.82957 1.000 79.57904  ? 237  ILE A HG13  1 
ATOM   4473 H  HG21  . ILE A 1 342 ? 14.88378  16.64222  9.01353  1.000 80.88968  ? 237  ILE A HG21  1 
ATOM   4474 H  HG22  . ILE A 1 342 ? 15.62793  15.95044  10.23467 1.000 80.88968  ? 237  ILE A HG22  1 
ATOM   4475 H  HG23  . ILE A 1 342 ? 14.26788  15.34090  9.68491  1.000 80.88968  ? 237  ILE A HG23  1 
ATOM   4476 H  HD11  . ILE A 1 342 ? 11.98323  19.14277  9.09906  1.000 85.77424  ? 237  ILE A HD11  1 
ATOM   4477 H  HD12  . ILE A 1 342 ? 13.06940  19.55378  10.18296 1.000 85.77424  ? 237  ILE A HD12  1 
ATOM   4478 H  HD13  . ILE A 1 342 ? 13.52271  18.86028  8.82757  1.000 85.77424  ? 237  ILE A HD13  1 
ATOM   4479 N  N     . ILE A 1 343 ? 15.81703  15.70453  13.03403 1.000 60.56438  ? 238  ILE A N     1 
ATOM   4480 C  CA    . ILE A 1 343 ? 16.89851  14.79007  13.38155 1.000 60.13054  ? 238  ILE A CA    1 
ATOM   4481 C  C     . ILE A 1 343 ? 16.46280  13.84623  14.49476 1.000 59.22678  ? 238  ILE A C     1 
ATOM   4482 O  O     . ILE A 1 343 ? 16.79517  12.65465  14.48067 1.000 62.30931  ? 238  ILE A O     1 
ATOM   4483 C  CB    . ILE A 1 343 ? 18.16647  15.58132  13.75747 1.000 62.26283  ? 238  ILE A CB    1 
ATOM   4484 C  CG1   . ILE A 1 343 ? 18.73957  16.23962  12.49711 1.000 67.35987  ? 238  ILE A CG1   1 
ATOM   4485 C  CG2   . ILE A 1 343 ? 19.19558  14.67456  14.43658 1.000 60.58210  ? 238  ILE A CG2   1 
ATOM   4486 C  CD1   . ILE A 1 343 ? 20.08955  16.89023  12.67957 1.000 70.94146  ? 238  ILE A CD1   1 
ATOM   4487 H  H     . ILE A 1 343 ? 15.96713  16.52908  13.22687 1.000 72.72047  ? 238  ILE A H     1 
ATOM   4488 H  HA    . ILE A 1 343 ? 17.10824  14.24897  12.60430 1.000 72.19986  ? 238  ILE A HA    1 
ATOM   4489 H  HB    . ILE A 1 343 ? 17.93432  16.27478  14.39476 1.000 74.75861  ? 238  ILE A HB    1 
ATOM   4490 H  HG12  . ILE A 1 343 ? 18.83368  15.56051  11.81092 1.000 80.87506  ? 238  ILE A HG12  1 
ATOM   4491 H  HG13  . ILE A 1 343 ? 18.12239  16.92696  12.20119 1.000 80.87506  ? 238  ILE A HG13  1 
ATOM   4492 H  HG21  . ILE A 1 343 ? 19.99392  15.19111  14.62821 1.000 72.74174  ? 238  ILE A HG21  1 
ATOM   4493 H  HG22  . ILE A 1 343 ? 18.81810  14.33083  15.26136 1.000 72.74174  ? 238  ILE A HG22  1 
ATOM   4494 H  HG23  . ILE A 1 343 ? 19.41173  13.94046  13.84054 1.000 72.74174  ? 238  ILE A HG23  1 
ATOM   4495 H  HD11  . ILE A 1 343 ? 20.32016  17.37164  11.86966 1.000 85.17297  ? 238  ILE A HD11  1 
ATOM   4496 H  HD12  . ILE A 1 343 ? 20.04517  17.50504  13.42854 1.000 85.17297  ? 238  ILE A HD12  1 
ATOM   4497 H  HD13  . ILE A 1 343 ? 20.75052  16.20231  12.85504 1.000 85.17297  ? 238  ILE A HD13  1 
ATOM   4498 N  N     . ALA A 1 344 ? 15.71721  14.35488  15.47598 1.000 55.17988  ? 239  ALA A N     1 
ATOM   4499 C  CA    . ALA A 1 344 ? 15.20678  13.48651  16.53109 1.000 57.93360  ? 239  ALA A CA    1 
ATOM   4500 C  C     . ALA A 1 344 ? 14.25858  12.43872  15.95961 1.000 57.75991  ? 239  ALA A C     1 
ATOM   4501 O  O     . ALA A 1 344 ? 14.34842  11.25107  16.29378 1.000 50.34712  ? 239  ALA A O     1 
ATOM   4502 C  CB    . ALA A 1 344 ? 14.50573  14.32028  17.60285 1.000 65.78672  ? 239  ALA A CB    1 
ATOM   4503 H  H     . ALA A 1 344 ? 15.49754  15.18292  15.55138 1.000 66.25907  ? 239  ALA A H     1 
ATOM   4504 H  HA    . ALA A 1 344 ? 15.95210  13.02714  16.94866 1.000 69.56353  ? 239  ALA A HA    1 
ATOM   4505 H  HB1   . ALA A 1 344 ? 14.18035  13.72943  18.29994 1.000 78.98728  ? 239  ALA A HB1   1 
ATOM   4506 H  HB2   . ALA A 1 344 ? 15.13935  14.95346  17.97501 1.000 78.98728  ? 239  ALA A HB2   1 
ATOM   4507 H  HB3   . ALA A 1 344 ? 13.76287  14.79483  17.19805 1.000 78.98728  ? 239  ALA A HB3   1 
ATOM   4508 N  N     . GLY A 1 345 ? 13.34126  12.86550  15.08954 1.000 58.12148  ? 240  GLY A N     1 
ATOM   4509 C  CA    . GLY A 1 345 ? 12.40850  11.92529  14.49121 1.000 54.39574  ? 240  GLY A CA    1 
ATOM   4510 C  C     . GLY A 1 345 ? 13.09040  10.89330  13.61349 1.000 54.37976  ? 240  GLY A C     1 
ATOM   4511 O  O     . GLY A 1 345 ? 12.68231  9.73113   13.57749 1.000 51.67496  ? 240  GLY A O     1 
ATOM   4512 H  H     . GLY A 1 345 ? 13.24266  13.68121  14.83558 1.000 69.78899  ? 240  GLY A H     1 
ATOM   4513 H  HA2   . GLY A 1 345 ? 11.93179  11.45771  15.19479 1.000 65.31810  ? 240  GLY A HA2   1 
ATOM   4514 H  HA3   . GLY A 1 345 ? 11.77012  12.41223  13.94691 1.000 65.31810  ? 240  GLY A HA3   1 
ATOM   4515 N  N     . LEU A 1 346 ? 14.13503  11.30492  12.88763 1.000 50.95268  ? 241  LEU A N     1 
ATOM   4516 C  CA    . LEU A 1 346 ? 14.88266  10.35280  12.07126 1.000 56.17655  ? 241  LEU A CA    1 
ATOM   4517 C  C     . LEU A 1 346 ? 15.60446  9.33190   12.94118 1.000 57.37176  ? 241  LEU A C     1 
ATOM   4518 O  O     . LEU A 1 346 ? 15.68389  8.14932   12.58537 1.000 54.93971  ? 241  LEU A O     1 
ATOM   4519 C  CB    . LEU A 1 346 ? 15.87603  11.09425  11.17898 1.000 61.45823  ? 241  LEU A CB    1 
ATOM   4520 C  CG    . LEU A 1 346 ? 15.28667  11.69624  9.90386  1.000 60.62664  ? 241  LEU A CG    1 
ATOM   4521 C  CD1   . LEU A 1 346 ? 16.19754  12.77721  9.35171  1.000 68.75372  ? 241  LEU A CD1   1 
ATOM   4522 C  CD2   . LEU A 1 346 ? 15.06007  10.61172  8.86460  1.000 67.86607  ? 241  LEU A CD2   1 
ATOM   4523 H  H     . LEU A 1 346 ? 14.42384  12.11422  12.85259 1.000 61.18644  ? 241  LEU A H     1 
ATOM   4524 H  HA    . LEU A 1 346 ? 14.26203  9.87640   11.49788 1.000 67.45507  ? 241  LEU A HA    1 
ATOM   4525 H  HB2   . LEU A 1 346 ? 16.26242  11.82157  11.69143 1.000 73.79309  ? 241  LEU A HB2   1 
ATOM   4526 H  HB3   . LEU A 1 346 ? 16.56996  10.47136  10.91184 1.000 73.79309  ? 241  LEU A HB3   1 
ATOM   4527 H  HG    . LEU A 1 346 ? 14.43113  12.10289  10.11265 1.000 72.79518  ? 241  LEU A HG    1 
ATOM   4528 H  HD11  . LEU A 1 346 ? 15.80278  13.14038  8.54351  1.000 82.54768  ? 241  LEU A HD11  1 
ATOM   4529 H  HD12  . LEU A 1 346 ? 16.29513  13.47752  10.01574 1.000 82.54768  ? 241  LEU A HD12  1 
ATOM   4530 H  HD13  . LEU A 1 346 ? 17.06335  12.38856  9.15116  1.000 82.54768  ? 241  LEU A HD13  1 
ATOM   4531 H  HD21  . LEU A 1 346 ? 14.68834  11.01414  8.06411  1.000 81.48250  ? 241  LEU A HD21  1 
ATOM   4532 H  HD22  . LEU A 1 346 ? 15.90862  10.18916  8.65894  1.000 81.48250  ? 241  LEU A HD22  1 
ATOM   4533 H  HD23  . LEU A 1 346 ? 14.44192  9.95549   9.22258  1.000 81.48250  ? 241  LEU A HD23  1 
ATOM   4534 N  N     . PHE A 1 347 ? 16.14793  9.77307   14.07810 1.000 51.18601  ? 242  PHE A N     1 
ATOM   4535 C  CA    . PHE A 1 347 ? 16.72583  8.83589   15.03552 1.000 49.35252  ? 242  PHE A CA    1 
ATOM   4536 C  C     . PHE A 1 347 ? 15.70116  7.78526   15.44284 1.000 45.10159  ? 242  PHE A C     1 
ATOM   4537 O  O     . PHE A 1 347 ? 15.99270  6.58366   15.45428 1.000 51.97296  ? 242  PHE A O     1 
ATOM   4538 C  CB    . PHE A 1 347 ? 17.23672  9.59496   16.26215 1.000 52.12957  ? 242  PHE A CB    1 
ATOM   4539 C  CG    . PHE A 1 347 ? 17.98669  8.73480   17.23850 1.000 45.62267  ? 242  PHE A CG    1 
ATOM   4540 C  CD1   . PHE A 1 347 ? 19.35158  8.55310   17.10850 1.000 48.72748  ? 242  PHE A CD1   1 
ATOM   4541 C  CD2   . PHE A 1 347 ? 17.32884  8.10544   18.28202 1.000 45.80856  ? 242  PHE A CD2   1 
ATOM   4542 C  CE1   . PHE A 1 347 ? 20.04978  7.76112   17.99910 1.000 49.66126  ? 242  PHE A CE1   1 
ATOM   4543 C  CE2   . PHE A 1 347 ? 18.02336  7.30929   19.17768 1.000 50.12995  ? 242  PHE A CE2   1 
ATOM   4544 C  CZ    . PHE A 1 347 ? 19.38651  7.13822   19.03433 1.000 47.36410  ? 242  PHE A CZ    1 
ATOM   4545 H  H     . PHE A 1 347 ? 16.19316  10.59889  14.31387 1.000 61.46643  ? 242  PHE A H     1 
ATOM   4546 H  HA    . PHE A 1 347 ? 17.48004  8.38461   14.62514 1.000 59.26624  ? 242  PHE A HA    1 
ATOM   4547 H  HB2   . PHE A 1 347 ? 17.83588  10.29809  15.96632 1.000 62.59870  ? 242  PHE A HB2   1 
ATOM   4548 H  HB3   . PHE A 1 347 ? 16.47835  9.97981   16.72869 1.000 62.59870  ? 242  PHE A HB3   1 
ATOM   4549 H  HD1   . PHE A 1 347 ? 19.80547  8.96986   16.41194 1.000 58.51620  ? 242  PHE A HD1   1 
ATOM   4550 H  HD2   . PHE A 1 347 ? 16.41122  8.21854   18.38246 1.000 55.01349  ? 242  PHE A HD2   1 
ATOM   4551 H  HE1   . PHE A 1 347 ? 20.96758  7.64817   17.90019 1.000 59.63673  ? 242  PHE A HE1   1 
ATOM   4552 H  HE2   . PHE A 1 347 ? 17.57240  6.89035   19.87483 1.000 60.19916  ? 242  PHE A HE2   1 
ATOM   4553 H  HZ    . PHE A 1 347 ? 19.85529  6.60439   19.63448 1.000 56.88014  ? 242  PHE A HZ    1 
ATOM   4554 N  N     . ALA A 1 348 ? 14.48703  8.22474   15.77776 1.000 47.85418  ? 243  ALA A N     1 
ATOM   4555 C  CA    . ALA A 1 348 ? 13.43367  7.28886   16.15294 1.000 50.94798  ? 243  ALA A CA    1 
ATOM   4556 C  C     . ALA A 1 348 ? 13.08863  6.36283   14.99395 1.000 54.83029  ? 243  ALA A C     1 
ATOM   4557 O  O     . ALA A 1 348 ? 12.99118  5.14156   15.16510 1.000 53.20112  ? 243  ALA A O     1 
ATOM   4558 C  CB    . ALA A 1 348 ? 12.19559  8.05806   16.61488 1.000 57.23166  ? 243  ALA A CB    1 
ATOM   4559 H  H     . ALA A 1 348 ? 14.25156  9.05169   15.79507 1.000 57.46823  ? 243  ALA A H     1 
ATOM   4560 H  HA    . ALA A 1 348 ? 13.74509  6.74383   16.89244 1.000 61.18079  ? 243  ALA A HA    1 
ATOM   4561 H  HB1   . ALA A 1 348 ? 11.50049  7.42448   16.85221 1.000 68.72121  ? 243  ALA A HB1   1 
ATOM   4562 H  HB2   . ALA A 1 348 ? 12.42873  8.59771   17.38645 1.000 68.72121  ? 243  ALA A HB2   1 
ATOM   4563 H  HB3   . ALA A 1 348 ? 11.89040  8.62859   15.89221 1.000 68.72121  ? 243  ALA A HB3   1 
ATOM   4564 N  N     . LEU A 1 349 ? 12.90416  6.93024   13.79918 1.000 57.30015  ? 244  LEU A N     1 
ATOM   4565 C  CA    . LEU A 1 349 ? 12.53351  6.12001   12.64358 1.000 59.62606  ? 244  LEU A CA    1 
ATOM   4566 C  C     . LEU A 1 349 ? 13.55410  5.01811   12.38967 1.000 59.13084  ? 244  LEU A C     1 
ATOM   4567 O  O     . LEU A 1 349 ? 13.18503  3.88201   12.06745 1.000 59.78199  ? 244  LEU A O     1 
ATOM   4568 C  CB    . LEU A 1 349 ? 12.39079  7.01075   11.40802 1.000 66.05094  ? 244  LEU A CB    1 
ATOM   4569 C  CG    . LEU A 1 349 ? 12.09279  6.29665   10.08704 1.000 74.09530  ? 244  LEU A CG    1 
ATOM   4570 C  CD1   . LEU A 1 349 ? 10.71641  5.64432   10.11908 1.000 78.85117  ? 244  LEU A CD1   1 
ATOM   4571 C  CD2   . LEU A 1 349 ? 12.20623  7.26284   8.91538  1.000 73.44549  ? 244  LEU A CD2   1 
ATOM   4572 H  H     . LEU A 1 349 ? 12.98667  7.77042   13.63520 1.000 68.80340  ? 244  LEU A H     1 
ATOM   4573 H  HA    . LEU A 1 349 ? 11.67633  5.70060   12.81749 1.000 71.59449  ? 244  LEU A HA    1 
ATOM   4574 H  HB2   . LEU A 1 349 ? 11.66334  7.63232   11.56732 1.000 79.30434  ? 244  LEU A HB2   1 
ATOM   4575 H  HB3   . LEU A 1 349 ? 13.22205  7.49632   11.28922 1.000 79.30434  ? 244  LEU A HB3   1 
ATOM   4576 H  HG    . LEU A 1 349 ? 12.74887  5.59373   9.95910  1.000 88.95757  ? 244  LEU A HG    1 
ATOM   4577 H  HD11  . LEU A 1 349 ? 10.55710  5.20128   9.27100  1.000 94.66463  ? 244  LEU A HD11  1 
ATOM   4578 H  HD12  . LEU A 1 349 ? 10.69065  4.99657   10.84064 1.000 94.66463  ? 244  LEU A HD12  1 
ATOM   4579 H  HD13  . LEU A 1 349 ? 10.04556  6.32946   10.26551 1.000 94.66463  ? 244  LEU A HD13  1 
ATOM   4580 H  HD21  . LEU A 1 349 ? 12.02284  6.78378   8.09211  1.000 88.17780  ? 244  LEU A HD21  1 
ATOM   4581 H  HD22  . LEU A 1 349 ? 11.56168  7.97821   9.03242  1.000 88.17780  ? 244  LEU A HD22  1 
ATOM   4582 H  HD23  . LEU A 1 349 ? 13.10475  7.62760   8.89270  1.000 88.17780  ? 244  LEU A HD23  1 
ATOM   4583 N  N     . CYS A 1 350 ? 14.84415  5.33311   12.53145 1.000 54.55642  ? 245  CYS A N     1 
ATOM   4584 C  CA    . CYS A 1 350 ? 15.88791  4.36991   12.19726 1.000 53.85259  ? 245  CYS A CA    1 
ATOM   4585 C  C     . CYS A 1 350 ? 16.03551  3.28811   13.25908 1.000 50.46638  ? 245  CYS A C     1 
ATOM   4586 O  O     . CYS A 1 350 ? 16.33353  2.13351   12.93147 1.000 48.90880  ? 245  CYS A O     1 
ATOM   4587 C  CB    . CYS A 1 350 ? 17.22143  5.09090   12.00503 1.000 48.96292  ? 245  CYS A CB    1 
ATOM   4588 S  SG    . CYS A 1 350 ? 17.28297  6.11929   10.53041 1.000 60.86664  ? 245  CYS A SG    1 
ATOM   4589 H  H     . CYS A 1 350 ? 15.13608  6.09024   12.81629 1.000 65.51092  ? 245  CYS A H     1 
ATOM   4590 H  HA    . CYS A 1 350 ? 15.64389  3.93826   11.36357 1.000 64.66632  ? 245  CYS A HA    1 
ATOM   4591 H  HB2   . CYS A 1 350 ? 17.37987  5.66309   12.77210 1.000 58.79871  ? 245  CYS A HB2   1 
ATOM   4592 H  HB3   . CYS A 1 350 ? 17.92651  4.42855   11.93394 1.000 58.79871  ? 245  CYS A HB3   1 
ATOM   4593 H  HG    . CYS A 1 350 ? 18.31530  6.73105   10.52355 1.000 73.08319  ? 245  CYS A HG    1 
ATOM   4594 N  N     . TRP A 1 351 ? 15.84656  3.63957   14.53001 1.000 50.55636  ? 246  TRP A N     1 
ATOM   4595 C  CA    . TRP A 1 351 ? 16.11466  2.70641   15.61730 1.000 57.54066  ? 246  TRP A CA    1 
ATOM   4596 C  C     . TRP A 1 351 ? 14.89662  1.89825   16.04194 1.000 52.08820  ? 246  TRP A C     1 
ATOM   4597 O  O     . TRP A 1 351 ? 15.05510  0.78570   16.55864 1.000 48.21003  ? 246  TRP A O     1 
ATOM   4598 C  CB    . TRP A 1 351 ? 16.66184  3.46459   16.82905 1.000 50.90493  ? 246  TRP A CB    1 
ATOM   4599 C  CG    . TRP A 1 351 ? 18.10812  3.81226   16.69588 1.000 48.33577  ? 246  TRP A CG    1 
ATOM   4600 C  CD1   . TRP A 1 351 ? 18.63337  4.97386   16.21039 1.000 43.94160  ? 246  TRP A CD1   1 
ATOM   4601 C  CD2   . TRP A 1 351 ? 19.22113  2.98355   17.04742 1.000 46.10854  ? 246  TRP A CD2   1 
ATOM   4602 N  NE1   . TRP A 1 351 ? 20.00590  4.92140   16.24215 1.000 44.02220  ? 246  TRP A NE1   1 
ATOM   4603 C  CE2   . TRP A 1 351 ? 20.39170  3.70863   16.75098 1.000 45.62317  ? 246  TRP A CE2   1 
ATOM   4604 C  CE3   . TRP A 1 351 ? 19.34117  1.69973   17.58713 1.000 43.66122  ? 246  TRP A CE3   1 
ATOM   4605 C  CZ2   . TRP A 1 351 ? 21.66628  3.19231   16.97649 1.000 46.01293  ? 246  TRP A CZ2   1 
ATOM   4606 C  CZ3   . TRP A 1 351 ? 20.60680  1.18940   17.80964 1.000 44.44975  ? 246  TRP A CZ3   1 
ATOM   4607 C  CH2   . TRP A 1 351 ? 21.75190  1.93411   17.50507 1.000 43.74496  ? 246  TRP A CH2   1 
ATOM   4608 H  H     . TRP A 1 351 ? 15.56459  4.41061   14.78610 1.000 60.71085  ? 246  TRP A H     1 
ATOM   4609 H  HA    . TRP A 1 351 ? 16.78792  2.07621   15.31651 1.000 69.09201  ? 246  TRP A HA    1 
ATOM   4610 H  HB2   . TRP A 1 351 ? 16.16414  4.29044   16.93471 1.000 61.12913  ? 246  TRP A HB2   1 
ATOM   4611 H  HB3   . TRP A 1 351 ? 16.55863  2.91162   17.61929 1.000 61.12913  ? 246  TRP A HB3   1 
ATOM   4612 H  HD1   . TRP A 1 351 ? 18.13491  5.69619   15.90268 1.000 52.77314  ? 246  TRP A HD1   1 
ATOM   4613 H  HE1   . TRP A 1 351 ? 20.53643  5.54741   15.98475 1.000 52.86986  ? 246  TRP A HE1   1 
ATOM   4614 H  HE3   . TRP A 1 351 ? 18.58493  1.19888   17.79242 1.000 52.43669  ? 246  TRP A HE3   1 
ATOM   4615 H  HZ2   . TRP A 1 351 ? 22.42926  3.68451   16.77524 1.000 55.25873  ? 246  TRP A HZ2   1 
ATOM   4616 H  HZ3   . TRP A 1 351 ? 20.69876  0.33618   18.16803 1.000 53.38291  ? 246  TRP A HZ3   1 
ATOM   4617 H  HH2   . TRP A 1 351 ? 22.59017  1.56484   17.66584 1.000 52.53717  ? 246  TRP A HH2   1 
ATOM   4618 N  N     . LEU A 1 352 ? 13.68907  2.41934   15.83778 1.000 55.55342  ? 247  LEU A N     1 
ATOM   4619 C  CA    . LEU A 1 352 ? 12.50633  1.72557   16.33750 1.000 57.58234  ? 247  LEU A CA    1 
ATOM   4620 C  C     . LEU A 1 352 ? 12.33031  0.33115   15.74973 1.000 54.17838  ? 247  LEU A C     1 
ATOM   4621 O  O     . LEU A 1 352 ? 11.95728  -0.58186  16.50765 1.000 54.64286  ? 247  LEU A O     1 
ATOM   4622 C  CB    . LEU A 1 352 ? 11.25982  2.58034   16.07890 1.000 60.43852  ? 247  LEU A CB    1 
ATOM   4623 C  CG    . LEU A 1 352 ? 10.99113  3.66301   17.12614 1.000 66.61299  ? 247  LEU A CG    1 
ATOM   4624 C  CD1   . LEU A 1 352 ? 9.87123   4.58242   16.66955 1.000 66.01028  ? 247  LEU A CD1   1 
ATOM   4625 C  CD2   . LEU A 1 352 ? 10.65590  3.03760   18.47657 1.000 67.10546  ? 247  LEU A CD2   1 
ATOM   4626 H  H     . LEU A 1 352 ? 13.53019  3.15570   15.42289 1.000 66.70732  ? 247  LEU A H     1 
ATOM   4627 H  HA    . LEU A 1 352 ? 12.61393  1.62274   17.29601 1.000 69.14202  ? 247  LEU A HA    1 
ATOM   4628 H  HB2   . LEU A 1 352 ? 11.36393  3.02279   15.22198 1.000 72.56945  ? 247  LEU A HB2   1 
ATOM   4629 H  HB3   . LEU A 1 352 ? 10.48607  1.99571   16.05857 1.000 72.56945  ? 247  LEU A HB3   1 
ATOM   4630 H  HG    . LEU A 1 352 ? 11.79307  4.19755   17.23595 1.000 79.97881  ? 247  LEU A HG    1 
ATOM   4631 H  HD11  . LEU A 1 352 ? 9.70130   5.24080   17.36133 1.000 79.25556  ? 247  LEU A HD11  1 
ATOM   4632 H  HD12  . LEU A 1 352 ? 10.14093  5.02578   15.85004 1.000 79.25556  ? 247  LEU A HD12  1 
ATOM   4633 H  HD13  . LEU A 1 352 ? 9.07306   4.05405   16.51254 1.000 79.25556  ? 247  LEU A HD13  1 
ATOM   4634 H  HD21  . LEU A 1 352 ? 10.31500  3.72682   19.06789 1.000 80.56977  ? 247  LEU A HD21  1 
ATOM   4635 H  HD22  . LEU A 1 352 ? 9.98393   2.34996   18.34805 1.000 80.56977  ? 247  LEU A HD22  1 
ATOM   4636 H  HD23  . LEU A 1 352 ? 11.46059  2.64760   18.85245 1.000 80.56977  ? 247  LEU A HD23  1 
ATOM   4637 N  N     . PRO A 1 353 ? 12.56074  0.09200   14.45463 1.000 56.57329  ? 248  PRO A N     1 
ATOM   4638 C  CA    . PRO A 1 353 ? 12.36786  -1.27195  13.92640 1.000 51.75687  ? 248  PRO A CA    1 
ATOM   4639 C  C     . PRO A 1 353 ? 13.11033  -2.34169  14.70798 1.000 54.04730  ? 248  PRO A C     1 
ATOM   4640 O  O     . PRO A 1 353 ? 12.53123  -3.39105  15.01614 1.000 53.34854  ? 248  PRO A O     1 
ATOM   4641 C  CB    . PRO A 1 353 ? 12.87787  -1.15456  12.48333 1.000 57.11824  ? 248  PRO A CB    1 
ATOM   4642 C  CG    . PRO A 1 353 ? 12.65140  0.27734   12.12424 1.000 58.11346  ? 248  PRO A CG    1 
ATOM   4643 C  CD    . PRO A 1 353 ? 12.89642  1.05713   13.39122 1.000 55.61425  ? 248  PRO A CD    1 
ATOM   4644 H  HA    . PRO A 1 353 ? 11.42096  -1.48228  13.92017 1.000 62.15146  ? 248  PRO A HA    1 
ATOM   4645 H  HB2   . PRO A 1 353 ? 13.82064  -1.37946  12.44454 1.000 68.58511  ? 248  PRO A HB2   1 
ATOM   4646 H  HB3   . PRO A 1 353 ? 12.37192  -1.74443  11.90284 1.000 68.58511  ? 248  PRO A HB3   1 
ATOM   4647 H  HG2   . PRO A 1 353 ? 13.27406  0.54393   11.42989 1.000 69.77937  ? 248  PRO A HG2   1 
ATOM   4648 H  HG3   . PRO A 1 353 ? 11.73953  0.39815   11.81637 1.000 69.77937  ? 248  PRO A HG3   1 
ATOM   4649 H  HD2   . PRO A 1 353 ? 13.82492  1.33070   13.45398 1.000 66.78032  ? 248  PRO A HD2   1 
ATOM   4650 H  HD3   . PRO A 1 353 ? 12.31782  1.83442   13.43541 1.000 66.78032  ? 248  PRO A HD3   1 
ATOM   4651 N  N     . LEU A 1 354 ? 14.38425  -2.10789  15.03845 1.000 52.03591  ? 249  LEU A N     1 
ATOM   4652 C  CA    . LEU A 1 354 ? 15.14085  -3.10331  15.79312 1.000 51.06118  ? 249  LEU A CA    1 
ATOM   4653 C  C     . LEU A 1 354 ? 14.53891  -3.31421  17.17671 1.000 51.38111  ? 249  LEU A C     1 
ATOM   4654 O  O     . LEU A 1 354 ? 14.40936  -4.45417  17.63968 1.000 49.15819  ? 249  LEU A O     1 
ATOM   4655 C  CB    . LEU A 1 354 ? 16.60401  -2.67574  15.90038 1.000 55.27901  ? 249  LEU A CB    1 
ATOM   4656 C  CG    . LEU A 1 354 ? 17.59988  -3.69275  16.46282 1.000 49.99318  ? 249  LEU A CG    1 
ATOM   4657 C  CD1   . LEU A 1 354 ? 17.55962  -4.99267  15.69072 1.000 59.26214  ? 249  LEU A CD1   1 
ATOM   4658 C  CD2   . LEU A 1 354 ? 19.00091  -3.11466  16.43023 1.000 54.35960  ? 249  LEU A CD2   1 
ATOM   4659 H  H     . LEU A 1 354 ? 14.82302  -1.39509  14.84101 1.000 62.48630  ? 249  LEU A H     1 
ATOM   4660 H  HA    . LEU A 1 354 ? 15.11042  -3.94943  15.31977 1.000 61.31664  ? 249  LEU A HA    1 
ATOM   4661 H  HB2   . LEU A 1 354 ? 16.91135  -2.44546  15.00964 1.000 66.37803  ? 249  LEU A HB2   1 
ATOM   4662 H  HB3   . LEU A 1 354 ? 16.64339  -1.89651  16.47670 1.000 66.37803  ? 249  LEU A HB3   1 
ATOM   4663 H  HG    . LEU A 1 354 ? 17.35569  -3.88904  17.38083 1.000 60.03503  ? 249  LEU A HG    1 
ATOM   4664 H  HD11  . LEU A 1 354 ? 18.31792  -5.53847  15.95147 1.000 71.15778  ? 249  LEU A HD11  1 
ATOM   4665 H  HD12  . LEU A 1 354 ? 16.73248  -5.45613  15.89553 1.000 71.15778  ? 249  LEU A HD12  1 
ATOM   4666 H  HD13  . LEU A 1 354 ? 17.60324  -4.79768  14.74152 1.000 71.15778  ? 249  LEU A HD13  1 
ATOM   4667 H  HD21  . LEU A 1 354 ? 19.63131  -3.79884  16.70483 1.000 65.27474  ? 249  LEU A HD21  1 
ATOM   4668 H  HD22  . LEU A 1 354 ? 19.20145  -2.82345  15.52697 1.000 65.27474  ? 249  LEU A HD22  1 
ATOM   4669 H  HD23  . LEU A 1 354 ? 19.04556  -2.36043  17.03853 1.000 65.27474  ? 249  LEU A HD23  1 
ATOM   4670 N  N     . HIS A 1 355 ? 14.15945  -2.22612  17.85120 1.000 48.87529  ? 250  HIS A N     1 
ATOM   4671 C  CA    . HIS A 1 355 ? 13.52483  -2.35801  19.15852 1.000 53.70660  ? 250  HIS A CA    1 
ATOM   4672 C  C     . HIS A 1 355 ? 12.20415  -3.11156  19.05719 1.000 48.90340  ? 250  HIS A C     1 
ATOM   4673 O  O     . HIS A 1 355 ? 11.87761  -3.92884  19.92630 1.000 46.84351  ? 250  HIS A O     1 
ATOM   4674 C  CB    . HIS A 1 355 ? 13.30697  -0.97708  19.77497 1.000 53.77058  ? 250  HIS A CB    1 
ATOM   4675 C  CG    . HIS A 1 355 ? 14.57440  -0.29004  20.17614 1.000 51.23189  ? 250  HIS A CG    1 
ATOM   4676 N  ND1   . HIS A 1 355 ? 15.40424  -0.77902  21.16178 1.000 51.55258  ? 250  HIS A ND1   1 
ATOM   4677 C  CD2   . HIS A 1 355 ? 15.15178  0.85042   19.72965 1.000 52.52348  ? 250  HIS A CD2   1 
ATOM   4678 C  CE1   . HIS A 1 355 ? 16.43960  0.02905   21.30341 1.000 50.52302  ? 250  HIS A CE1   1 
ATOM   4679 N  NE2   . HIS A 1 355 ? 16.31107  1.02516   20.44571 1.000 46.94631  ? 250  HIS A NE2   1 
ATOM   4680 H  H     . HIS A 1 355 ? 14.25694  -1.41656  17.57789 1.000 58.69356  ? 250  HIS A H     1 
ATOM   4681 H  HA    . HIS A 1 355 ? 14.11369  -2.86042  19.74311 1.000 64.49114  ? 250  HIS A HA    1 
ATOM   4682 H  HB2   . HIS A 1 355 ? 12.85697  -0.41336  19.12642 1.000 64.56791  ? 250  HIS A HB2   1 
ATOM   4683 H  HB3   . HIS A 1 355 ? 12.75791  -1.07289  20.56886 1.000 64.56791  ? 250  HIS A HB3   1 
ATOM   4684 H  HD1   . HIS A 1 355 ? 15.26915  -1.49794  21.61400 1.000 61.90631  ? 250  HIS A HD1   1 
ATOM   4685 H  HD2   . HIS A 1 355 ? 14.82480  1.41051   19.06311 1.000 63.07139  ? 250  HIS A HD2   1 
ATOM   4686 H  HE1   . HIS A 1 355 ? 17.13991  -0.08420  21.90478 1.000 60.67084  ? 250  HIS A HE1   1 
ATOM   4687 N  N     . ILE A 1 356 ? 11.43100  -2.85118  18.00117 1.000 55.36090  ? 251  ILE A N     1 
ATOM   4688 C  CA    . ILE A 1 356 ? 10.14935  -3.52904  17.83510 1.000 55.49587  ? 251  ILE A CA    1 
ATOM   4689 C  C     . ILE A 1 356 ? 10.36226  -5.01269  17.57231 1.000 54.80589  ? 251  ILE A C     1 
ATOM   4690 O  O     . ILE A 1 356 ? 9.61359   -5.86003  18.07405 1.000 53.39373  ? 251  ILE A O     1 
ATOM   4691 C  CB    . ILE A 1 356 ? 9.33976   -2.86147  16.70864 1.000 54.68653  ? 251  ILE A CB    1 
ATOM   4692 C  CG1   . ILE A 1 356 ? 8.95436   -1.43631  17.11547 1.000 61.37498  ? 251  ILE A CG1   1 
ATOM   4693 C  CG2   . ILE A 1 356 ? 8.09867   -3.68058  16.38508 1.000 58.37393  ? 251  ILE A CG2   1 
ATOM   4694 C  CD1   . ILE A 1 356 ? 8.48035   -0.57562  15.96596 1.000 65.42779  ? 251  ILE A CD1   1 
ATOM   4695 H  H     . ILE A 1 356 ? 11.62416  -2.29349  17.37565 1.000 66.47629  ? 251  ILE A H     1 
ATOM   4696 H  HA    . ILE A 1 356 ? 9.64420   -3.44360  18.65877 1.000 66.63826  ? 251  ILE A HA    1 
ATOM   4697 H  HB    . ILE A 1 356 ? 9.89255   -2.81995  15.91265 1.000 65.66705  ? 251  ILE A HB    1 
ATOM   4698 H  HG12  . ILE A 1 356 ? 8.23595   -1.48203  17.76562 1.000 73.69320  ? 251  ILE A HG12  1 
ATOM   4699 H  HG13  . ILE A 1 356 ? 9.72947   -1.00442  17.50736 1.000 73.69320  ? 251  ILE A HG13  1 
ATOM   4700 H  HG21  . ILE A 1 356 ? 7.50563   -3.14973  15.83065 1.000 70.09193  ? 251  ILE A HG21  1 
ATOM   4701 H  HG22  . ILE A 1 356 ? 8.36506   -4.48335  15.91023 1.000 70.09193  ? 251  ILE A HG22  1 
ATOM   4702 H  HG23  . ILE A 1 356 ? 7.65269   -3.91858  17.21295 1.000 70.09193  ? 251  ILE A HG23  1 
ATOM   4703 H  HD11  . ILE A 1 356 ? 8.27412   0.31148   16.29976 1.000 78.55657  ? 251  ILE A HD11  1 
ATOM   4704 H  HD12  . ILE A 1 356 ? 9.18350   -0.52318  15.29982 1.000 78.55657  ? 251  ILE A HD12  1 
ATOM   4705 H  HD13  . ILE A 1 356 ? 7.68648   -0.97594  15.57813 1.000 78.55657  ? 251  ILE A HD13  1 
ATOM   4706 N  N     . ILE A 1 357 ? 11.37918  -5.35335  16.77932 1.000 52.59515  ? 252  ILE A N     1 
ATOM   4707 C  CA    . ILE A 1 357 ? 11.70452  -6.76013  16.56931 1.000 50.57420  ? 252  ILE A CA    1 
ATOM   4708 C  C     . ILE A 1 357 ? 12.06164  -7.41966  17.89422 1.000 52.40963  ? 252  ILE A C     1 
ATOM   4709 O  O     . ILE A 1 357 ? 11.65352  -8.55466  18.17166 1.000 49.58023  ? 252  ILE A O     1 
ATOM   4710 C  CB    . ILE A 1 357 ? 12.84106  -6.90028  15.53957 1.000 51.96931  ? 252  ILE A CB    1 
ATOM   4711 C  CG1   . ILE A 1 357 ? 12.33341  -6.50958  14.14782 1.000 58.79475  ? 252  ILE A CG1   1 
ATOM   4712 C  CG2   . ILE A 1 357 ? 13.39002  -8.31999  15.55802 1.000 50.20066  ? 252  ILE A CG2   1 
ATOM   4713 C  CD1   . ILE A 1 357 ? 13.42464  -6.35849  13.10313 1.000 55.35782  ? 252  ILE A CD1   1 
ATOM   4714 H  H     . ILE A 1 357 ? 11.88569  -4.79911  16.35996 1.000 63.15740  ? 252  ILE A H     1 
ATOM   4715 H  HA    . ILE A 1 357 ? 10.92312  -7.20904  16.21043 1.000 60.73225  ? 252  ILE A HA    1 
ATOM   4716 H  HB    . ILE A 1 357 ? 13.56448  -6.29823  15.77431 1.000 62.40638  ? 252  ILE A HB    1 
ATOM   4717 H  HG12  . ILE A 1 357 ? 11.72261  -7.19606  13.83709 1.000 70.59691  ? 252  ILE A HG12  1 
ATOM   4718 H  HG13  . ILE A 1 357 ? 11.87101  -5.65948  14.21432 1.000 70.59691  ? 252  ILE A HG13  1 
ATOM   4719 H  HG21  . ILE A 1 357 ? 13.87319  -8.48249  14.73276 1.000 60.28401  ? 252  ILE A HG21  1 
ATOM   4720 H  HG22  . ILE A 1 357 ? 13.98751  -8.41772  16.31588 1.000 60.28401  ? 252  ILE A HG22  1 
ATOM   4721 H  HG23  . ILE A 1 357 ? 12.65102  -8.94333  15.63688 1.000 60.28401  ? 252  ILE A HG23  1 
ATOM   4722 H  HD11  . ILE A 1 357 ? 13.02889  -6.03969  12.27691 1.000 66.47260  ? 252  ILE A HD11  1 
ATOM   4723 H  HD12  . ILE A 1 357 ? 14.08177  -5.72063  13.42283 1.000 66.47260  ? 252  ILE A HD12  1 
ATOM   4724 H  HD13  . ILE A 1 357 ? 13.84422  -7.22088  12.95773 1.000 66.47260  ? 252  ILE A HD13  1 
ATOM   4725 N  N     . ASN A 1 358 ? 12.82359  -6.71860  18.73675 1.000 49.26103  ? 253  ASN A N     1 
ATOM   4726 C  CA    . ASN A 1 358 ? 13.13817  -7.25394  20.05574 1.000 48.58451  ? 253  ASN A CA    1 
ATOM   4727 C  C     . ASN A 1 358 ? 11.87296  -7.45571  20.87968 1.000 47.62122  ? 253  ASN A C     1 
ATOM   4728 O  O     . ASN A 1 358 ? 11.75101  -8.44626  21.61025 1.000 54.57617  ? 253  ASN A O     1 
ATOM   4729 C  CB    . ASN A 1 358 ? 14.11369  -6.32558  20.77799 1.000 50.80608  ? 253  ASN A CB    1 
ATOM   4730 C  CG    . ASN A 1 358 ? 15.48883  -6.32268  20.14263 1.000 46.06175  ? 253  ASN A CG    1 
ATOM   4731 O  OD1   . ASN A 1 358 ? 15.84033  -7.23698  19.39731 1.000 52.59776  ? 253  ASN A OD1   1 
ATOM   4732 N  ND2   . ASN A 1 358 ? 16.27805  -5.29787  20.44024 1.000 45.34300  ? 253  ASN A ND2   1 
ATOM   4733 H  H     . ASN A 1 358 ? 13.16301  -5.94615  18.57025 1.000 59.15645  ? 253  ASN A H     1 
ATOM   4734 H  HA    . ASN A 1 358 ? 13.56964  -8.11656  19.95268 1.000 58.34463  ? 253  ASN A HA    1 
ATOM   4735 H  HB2   . ASN A 1 358 ? 13.76792  -5.41969  20.75161 1.000 61.01051  ? 253  ASN A HB2   1 
ATOM   4736 H  HB3   . ASN A 1 358 ? 14.20772  -6.61814  21.69802 1.000 61.01051  ? 253  ASN A HB3   1 
ATOM   4737 H  HD21  . ASN A 1 358 ? 17.06821  -5.25179  20.10390 1.000 54.45482  ? 253  ASN A HD21  1 
ATOM   4738 H  HD22  . ASN A 1 358 ? 15.99926  -4.67993  20.96942 1.000 54.45482  ? 253  ASN A HD22  1 
ATOM   4739 N  N     . CYS A 1 359 ? 10.91483  -6.53131  20.77015 1.000 50.55047  ? 254  CYS A N     1 
ATOM   4740 C  CA    . CYS A 1 359 ? 9.65681   -6.68777  21.49428 1.000 57.17819  ? 254  CYS A CA    1 
ATOM   4741 C  C     . CYS A 1 359 ? 8.93371   -7.95731  21.06844 1.000 54.18022  ? 254  CYS A C     1 
ATOM   4742 O  O     . CYS A 1 359 ? 8.34845   -8.65785  21.90202 1.000 56.86299  ? 254  CYS A O     1 
ATOM   4743 C  CB    . CYS A 1 359 ? 8.76289   -5.46863  21.27182 1.000 59.57189  ? 254  CYS A CB    1 
ATOM   4744 S  SG    . CYS A 1 359 ? 9.39030   -3.96339  22.03239 1.000 66.06697  ? 254  CYS A SG    1 
ATOM   4745 H  H     . CYS A 1 359 ? 10.96875  -5.81860  20.29188 1.000 60.70379  ? 254  CYS A H     1 
ATOM   4746 H  HA    . CYS A 1 359 ? 9.85045   -6.74947  22.44275 1.000 68.65704  ? 254  CYS A HA    1 
ATOM   4747 H  HB2   . CYS A 1 359 ? 8.68501   -5.30877  20.31826 1.000 71.52949  ? 254  CYS A HB2   1 
ATOM   4748 H  HB3   . CYS A 1 359 ? 7.88838   -5.64982  21.65035 1.000 71.52949  ? 254  CYS A HB3   1 
ATOM   4749 H  HG    . CYS A 1 359 ? 8.71523   -3.03638  21.67893 1.000 79.32358  ? 254  CYS A HG    1 
ATOM   4750 N  N     . PHE A 1 360 ? 8.95642   -8.26871  19.77254 1.000 54.82690  ? 255  PHE A N     1 
ATOM   4751 C  CA    . PHE A 1 360 ? 8.33489   -9.50458  19.31154 1.000 60.25680  ? 255  PHE A CA    1 
ATOM   4752 C  C     . PHE A 1 360 ? 9.11113   -10.72163 19.79609 1.000 58.30697  ? 255  PHE A C     1 
ATOM   4753 O  O     . PHE A 1 360 ? 8.51403   -11.71956 20.21582 1.000 61.39119  ? 255  PHE A O     1 
ATOM   4754 C  CB    . PHE A 1 360 ? 8.23208   -9.50390  17.78749 1.000 60.81662  ? 255  PHE A CB    1 
ATOM   4755 C  CG    . PHE A 1 360 ? 7.01197   -8.80500  17.26466 1.000 63.92132  ? 255  PHE A CG    1 
ATOM   4756 C  CD1   . PHE A 1 360 ? 7.03737   -7.44882  16.98273 1.000 66.87726  ? 255  PHE A CD1   1 
ATOM   4757 C  CD2   . PHE A 1 360 ? 5.83666   -9.50670  17.05635 1.000 70.80693  ? 255  PHE A CD2   1 
ATOM   4758 C  CE1   . PHE A 1 360 ? 5.91062   -6.80585  16.50124 1.000 69.94822  ? 255  PHE A CE1   1 
ATOM   4759 C  CE2   . PHE A 1 360 ? 4.70841   -8.87121  16.57553 1.000 75.24227  ? 255  PHE A CE2   1 
ATOM   4760 C  CZ    . PHE A 1 360 ? 4.74464   -7.51870  16.29757 1.000 72.95216  ? 255  PHE A CZ    1 
ATOM   4761 H  H     . PHE A 1 360 ? 9.31731   -7.79162  19.15468 1.000 65.83549  ? 255  PHE A H     1 
ATOM   4762 H  HA    . PHE A 1 360 ? 7.43554   -9.55699  19.67115 1.000 72.35138  ? 255  PHE A HA    1 
ATOM   4763 H  HB2   . PHE A 1 360 ? 9.01016   -9.05411  17.42257 1.000 73.02316  ? 255  PHE A HB2   1 
ATOM   4764 H  HB3   . PHE A 1 360 ? 8.20343   -10.42221 17.47638 1.000 73.02316  ? 255  PHE A HB3   1 
ATOM   4765 H  HD1   . PHE A 1 360 ? 7.82014   -6.96535  17.11853 1.000 80.29593  ? 255  PHE A HD1   1 
ATOM   4766 H  HD2   . PHE A 1 360 ? 5.80648   -10.41738 17.24251 1.000 85.01154  ? 255  PHE A HD2   1 
ATOM   4767 H  HE1   . PHE A 1 360 ? 5.93811   -5.89511  16.31496 1.000 83.98108  ? 255  PHE A HE1   1 
ATOM   4768 H  HE2   . PHE A 1 360 ? 3.92507   -9.35357  16.43907 1.000 90.33394  ? 255  PHE A HE2   1 
ATOM   4769 H  HZ    . PHE A 1 360 ? 3.98602   -7.08886  15.97410 1.000 87.58581  ? 255  PHE A HZ    1 
ATOM   4770 N  N     . THR A 1 361 ? 10.44313  -10.65616 19.75177 1.000 52.91123  ? 256  THR A N     1 
ATOM   4771 C  CA    . THR A 1 361 ? 11.24978  -11.77750 20.21684 1.000 54.51197  ? 256  THR A CA    1 
ATOM   4772 C  C     . THR A 1 361 ? 11.03465  -12.04525 21.69971 1.000 54.22813  ? 256  THR A C     1 
ATOM   4773 O  O     . THR A 1 361 ? 11.15482  -13.19094 22.14748 1.000 57.11959  ? 256  THR A O     1 
ATOM   4774 C  CB    . THR A 1 361 ? 12.73030  -11.50598 19.94309 1.000 55.14826  ? 256  THR A CB    1 
ATOM   4775 O  OG1   . THR A 1 361 ? 12.92414  -11.26391 18.54280 1.000 51.78664  ? 256  THR A OG1   1 
ATOM   4776 C  CG2   . THR A 1 361 ? 13.58857  -12.69357 20.38685 1.000 53.72011  ? 256  THR A CG2   1 
ATOM   4777 H  H     . THR A 1 361 ? 10.89476  -9.98432  19.46148 1.000 63.53670  ? 256  THR A H     1 
ATOM   4778 H  HA    . THR A 1 361 ? 10.98996  -12.57226 19.72515 1.000 65.45757  ? 256  THR A HA    1 
ATOM   4779 H  HB    . THR A 1 361 ? 13.01507  -10.72601 20.44453 1.000 66.22113  ? 256  THR A HB    1 
ATOM   4780 H  HG1   . THR A 1 361 ? 13.73898  -11.13653 18.38336 1.000 62.18718  ? 256  THR A HG1   1 
ATOM   4781 H  HG21  . THR A 1 361 ? 14.49953  -12.57997 20.07357 1.000 64.50735  ? 256  THR A HG21  1 
ATOM   4782 H  HG22  . THR A 1 361 ? 13.59400  -12.75563 21.35484 1.000 64.50735  ? 256  THR A HG22  1 
ATOM   4783 H  HG23  . THR A 1 361 ? 13.23013  -13.51716 20.02061 1.000 64.50735  ? 256  THR A HG23  1 
ATOM   4784 N  N     . PHE A 1 362 ? 10.71431  -11.00893 22.47211 1.000 58.95752  ? 257  PHE A N     1 
ATOM   4785 C  CA    . PHE A 1 362 ? 10.59530  -11.12127 23.92042 1.000 58.56433  ? 257  PHE A CA    1 
ATOM   4786 C  C     . PHE A 1 362 ? 9.16200   -11.40102 24.36203 1.000 58.70995  ? 257  PHE A C     1 
ATOM   4787 O  O     . PHE A 1 362 ? 8.92656   -12.30309 25.17097 1.000 56.81304  ? 257  PHE A O     1 
ATOM   4788 C  CB    . PHE A 1 362 ? 11.11608  -9.83535  24.57594 1.000 53.54197  ? 257  PHE A CB    1 
ATOM   4789 C  CG    . PHE A 1 362 ? 10.99783  -9.81965  26.07500 1.000 54.15735  ? 257  PHE A CG    1 
ATOM   4790 C  CD1   . PHE A 1 362 ? 11.80193  -10.63248 26.85725 1.000 50.96651  ? 257  PHE A CD1   1 
ATOM   4791 C  CD2   . PHE A 1 362 ? 10.09382  -8.97728  26.70215 1.000 54.11306  ? 257  PHE A CD2   1 
ATOM   4792 C  CE1   . PHE A 1 362 ? 11.69772  -10.61463 28.23650 1.000 56.45112  ? 257  PHE A CE1   1 
ATOM   4793 C  CE2   . PHE A 1 362 ? 9.98637   -8.95418  28.07973 1.000 56.50655  ? 257  PHE A CE2   1 
ATOM   4794 C  CZ    . PHE A 1 362 ? 10.78957  -9.77405  28.84787 1.000 59.00354  ? 257  PHE A CZ    1 
ATOM   4795 H  H     . PHE A 1 362 ? 10.55866  -10.21720 22.17455 1.000 70.79224  ? 257  PHE A H     1 
ATOM   4796 H  HA    . PHE A 1 362 ? 11.14162  -11.86288 24.22449 1.000 70.32041  ? 257  PHE A HA    1 
ATOM   4797 H  HB2   . PHE A 1 362 ? 12.05440  -9.73115  24.35324 1.000 64.29358  ? 257  PHE A HB2   1 
ATOM   4798 H  HB3   . PHE A 1 362 ? 10.60811  -9.08381  24.23237 1.000 64.29358  ? 257  PHE A HB3   1 
ATOM   4799 H  HD1   . PHE A 1 362 ? 12.41907  -11.19678 26.45031 1.000 61.20303  ? 257  PHE A HD1   1 
ATOM   4800 H  HD2   . PHE A 1 362 ? 9.55284   -8.42074  26.18979 1.000 64.97889  ? 257  PHE A HD2   1 
ATOM   4801 H  HE1   . PHE A 1 362 ? 12.23905  -11.16850 28.75137 1.000 67.78456  ? 257  PHE A HE1   1 
ATOM   4802 H  HE2   . PHE A 1 362 ? 9.37364   -8.38694  28.48923 1.000 67.85108  ? 257  PHE A HE2   1 
ATOM   4803 H  HZ    . PHE A 1 362 ? 10.71868  -9.75980  29.77505 1.000 70.84747  ? 257  PHE A HZ    1 
ATOM   4804 N  N     . PHE A 1 363 ? 8.19483   -10.64638 23.83681 1.000 63.74982  ? 258  PHE A N     1 
ATOM   4805 C  CA    . PHE A 1 363 ? 6.81957   -10.75909 24.30552 1.000 64.40804  ? 258  PHE A CA    1 
ATOM   4806 C  C     . PHE A 1 363 ? 6.05447   -11.90143 23.65001 1.000 66.08182  ? 258  PHE A C     1 
ATOM   4807 O  O     . PHE A 1 363 ? 5.01649   -12.31085 24.18078 1.000 69.74931  ? 258  PHE A O     1 
ATOM   4808 C  CB    . PHE A 1 363 ? 6.06712   -9.44478  24.06752 1.000 64.26240  ? 258  PHE A CB    1 
ATOM   4809 C  CG    . PHE A 1 363 ? 6.47751   -8.33268  24.99319 1.000 58.82420  ? 258  PHE A CG    1 
ATOM   4810 C  CD1   . PHE A 1 363 ? 6.35671   -8.47691  26.36583 1.000 55.80011  ? 258  PHE A CD1   1 
ATOM   4811 C  CD2   . PHE A 1 363 ? 6.97011   -7.13895  24.49150 1.000 61.11083  ? 258  PHE A CD2   1 
ATOM   4812 C  CE1   . PHE A 1 363 ? 6.73116   -7.45869  27.22034 1.000 58.28084  ? 258  PHE A CE1   1 
ATOM   4813 C  CE2   . PHE A 1 363 ? 7.34403   -6.11453  25.34204 1.000 66.23604  ? 258  PHE A CE2   1 
ATOM   4814 C  CZ    . PHE A 1 363 ? 7.22455   -6.27492  26.70816 1.000 57.32037  ? 258  PHE A CZ    1 
ATOM   4815 H  H     . PHE A 1 363 ? 8.31130   -10.06651 23.21248 1.000 76.54299  ? 258  PHE A H     1 
ATOM   4816 H  HA    . PHE A 1 363 ? 6.84126   -10.92716 25.26061 1.000 77.33286  ? 258  PHE A HA    1 
ATOM   4817 H  HB2   . PHE A 1 363 ? 6.23480   -9.15002  23.15873 1.000 77.15810  ? 258  PHE A HB2   1 
ATOM   4818 H  HB3   . PHE A 1 363 ? 5.11847   -9.60131  24.19582 1.000 77.15810  ? 258  PHE A HB3   1 
ATOM   4819 H  HD1   . PHE A 1 363 ? 6.01918   -9.26950  26.71622 1.000 67.00335  ? 258  PHE A HD1   1 
ATOM   4820 H  HD2   . PHE A 1 363 ? 7.05028   -7.02516  23.57198 1.000 73.37621  ? 258  PHE A HD2   1 
ATOM   4821 H  HE1   . PHE A 1 363 ? 6.65111   -7.57013  28.14016 1.000 69.98023  ? 258  PHE A HE1   1 
ATOM   4822 H  HE2   . PHE A 1 363 ? 7.67564   -5.31836  24.99412 1.000 79.52646  ? 258  PHE A HE2   1 
ATOM   4823 H  HZ    . PHE A 1 363 ? 7.47570   -5.58749  27.28198 1.000 68.82766  ? 258  PHE A HZ    1 
ATOM   4824 N  N     . CYS A 1 364 ? 6.52994   -12.42468 22.51921 1.000 69.22853  ? 259  CYS A N     1 
ATOM   4825 C  CA    . CYS A 1 364 ? 5.87019   -13.52974 21.82563 1.000 72.59219  ? 259  CYS A CA    1 
ATOM   4826 C  C     . CYS A 1 364 ? 6.86221   -14.66032 21.59117 1.000 70.57278  ? 259  CYS A C     1 
ATOM   4827 O  O     . CYS A 1 364 ? 7.47273   -14.75634 20.51752 1.000 70.85846  ? 259  CYS A O     1 
ATOM   4828 C  CB    . CYS A 1 364 ? 5.26260   -13.08240 20.49388 1.000 71.23183  ? 259  CYS A CB    1 
ATOM   4829 S  SG    . CYS A 1 364 ? 4.35866   -14.42418 19.67684 1.000 77.76485  ? 259  CYS A SG    1 
ATOM   4830 H  H     . CYS A 1 364 ? 7.24562   -12.15068 22.12893 1.000 83.11745  ? 259  CYS A H     1 
ATOM   4831 H  HA    . CYS A 1 364 ? 5.16542   -13.85680 22.40635 1.000 87.15384  ? 259  CYS A HA    1 
ATOM   4832 H  HB2   . CYS A 1 364 ? 4.64370   -12.35308 20.65497 1.000 85.52141  ? 259  CYS A HB2   1 
ATOM   4833 H  HB3   . CYS A 1 364 ? 5.97304   -12.78997 19.90172 1.000 85.52141  ? 259  CYS A HB3   1 
ATOM   4834 N  N     . PRO A 1 365 ? 7.04868   -15.54132 22.57739 1.000 76.26555  ? 260  PRO A N     1 
ATOM   4835 C  CA    . PRO A 1 365 ? 7.82323   -16.76542 22.31836 1.000 84.93035  ? 260  PRO A CA    1 
ATOM   4836 C  C     . PRO A 1 365 ? 7.11704   -17.73051 21.38277 1.000 89.19588  ? 260  PRO A C     1 
ATOM   4837 O  O     . PRO A 1 365 ? 7.78343   -18.58016 20.77866 1.000 94.35317  ? 260  PRO A O     1 
ATOM   4838 C  CB    . PRO A 1 365 ? 8.01063   -17.37151 23.71672 1.000 95.18035  ? 260  PRO A CB    1 
ATOM   4839 C  CG    . PRO A 1 365 ? 6.89370   -16.81081 24.53029 1.000 88.22960  ? 260  PRO A CG    1 
ATOM   4840 C  CD    . PRO A 1 365 ? 6.63922   -15.42914 23.98866 1.000 83.07624  ? 260  PRO A CD    1 
ATOM   4841 H  HA    . PRO A 1 365 ? 8.69466   -16.54337 21.95477 1.000 101.95964 ? 260  PRO A HA    1 
ATOM   4842 H  HB2   . PRO A 1 365 ? 7.95377   -18.33862 23.66818 1.000 114.25964 ? 260  PRO A HB2   1 
ATOM   4843 H  HB3   . PRO A 1 365 ? 8.87091   -17.10752 24.07885 1.000 114.25964 ? 260  PRO A HB3   1 
ATOM   4844 H  HG2   . PRO A 1 365 ? 6.10605   -17.36832 24.43186 1.000 105.91873 ? 260  PRO A HG2   1 
ATOM   4845 H  HG3   . PRO A 1 365 ? 7.15719   -16.77052 25.46295 1.000 105.91873 ? 260  PRO A HG3   1 
ATOM   4846 H  HD2   . PRO A 1 365 ? 5.69980   -15.19791 24.05877 1.000 99.73470  ? 260  PRO A HD2   1 
ATOM   4847 H  HD3   . PRO A 1 365 ? 7.17858   -14.77067 24.45385 1.000 99.73470  ? 260  PRO A HD3   1 
ATOM   4848 N  N     . ASP A 1 366 ? 5.79225   -17.62763 21.24413 1.000 86.46449  ? 261  ASP A N     1 
ATOM   4849 C  CA    . ASP A 1 366 ? 5.07080   -18.45674 20.28731 1.000 84.72232  ? 261  ASP A CA    1 
ATOM   4850 C  C     . ASP A 1 366 ? 5.34767   -18.04828 18.84624 1.000 89.08009  ? 261  ASP A C     1 
ATOM   4851 O  O     . ASP A 1 366 ? 5.19024   -18.87449 17.94103 1.000 86.22670  ? 261  ASP A O     1 
ATOM   4852 C  CB    . ASP A 1 366 ? 3.56486   -18.38746 20.55574 1.000 91.31166  ? 261  ASP A CB    1 
ATOM   4853 C  CG    . ASP A 1 366 ? 3.05732   -19.56349 21.37190 1.000 95.61105  ? 261  ASP A CG    1 
ATOM   4854 O  OD1   . ASP A 1 366 ? 3.88339   -20.28432 21.97134 1.000 97.66809  ? 261  ASP A OD1   1 
ATOM   4855 O  OD2   . ASP A 1 366 ? 1.82504   -19.76964 21.40723 1.000 98.45101  ? 261  ASP A OD2   1 
ATOM   4856 H  H     . ASP A 1 366 ? 5.29402   -17.08766 21.69111 1.000 103.80060 ? 261  ASP A H     1 
ATOM   4857 H  HA    . ASP A 1 366 ? 5.35626   -19.37654 20.40294 1.000 101.71000 ? 261  ASP A HA    1 
ATOM   4858 H  HB2   . ASP A 1 366 ? 3.36871   -17.57460 21.04737 1.000 109.61721 ? 261  ASP A HB2   1 
ATOM   4859 H  HB3   . ASP A 1 366 ? 3.09277   -18.38477 19.70838 1.000 109.61721 ? 261  ASP A HB3   1 
ATOM   4860 N  N     . CYS A 1 367 ? 5.74813   -16.80099 18.61321 1.000 88.71411  ? 262  CYS A N     1 
ATOM   4861 C  CA    . CYS A 1 367 ? 6.03631   -16.33881 17.26535 1.000 75.69834  ? 262  CYS A CA    1 
ATOM   4862 C  C     . CYS A 1 367 ? 7.38920   -16.85823 16.79631 1.000 77.71350  ? 262  CYS A C     1 
ATOM   4863 O  O     . CYS A 1 367 ? 8.32029   -17.03776 17.58646 1.000 79.07814  ? 262  CYS A O     1 
ATOM   4864 C  CB    . CYS A 1 367 ? 6.03557   -14.81112 17.20139 1.000 76.89093  ? 262  CYS A CB    1 
ATOM   4865 S  SG    . CYS A 1 367 ? 4.48987   -14.02593 17.69206 1.000 77.76325  ? 262  CYS A SG    1 
ATOM   4866 H  H     . CYS A 1 367 ? 5.86004   -16.20388 19.22192 1.000 106.50015 ? 262  CYS A H     1 
ATOM   4867 H  HA    . CYS A 1 367 ? 5.34937   -16.67058 16.66623 1.000 90.88123  ? 262  CYS A HA    1 
ATOM   4868 H  HB2   . CYS A 1 367 ? 6.73005   -14.47937 17.79176 1.000 92.31233  ? 262  CYS A HB2   1 
ATOM   4869 H  HB3   . CYS A 1 367 ? 6.22052   -14.54258 16.28783 1.000 92.31233  ? 262  CYS A HB3   1 
ATOM   4870 N  N     . SER A 1 368 ? 7.48955   -17.09972 15.49331 1.000 77.63517  ? 263  SER A N     1 
ATOM   4871 C  CA    . SER A 1 368 ? 8.77767   -17.41281 14.89364 1.000 74.95478  ? 263  SER A CA    1 
ATOM   4872 C  C     . SER A 1 368 ? 9.67202   -16.17984 14.91761 1.000 68.36688  ? 263  SER A C     1 
ATOM   4873 O  O     . SER A 1 368 ? 9.23094   -15.06575 14.62039 1.000 67.29685  ? 263  SER A O     1 
ATOM   4874 C  CB    . SER A 1 368 ? 8.59456   -17.90558 13.45984 1.000 75.93114  ? 263  SER A CB    1 
ATOM   4875 O  OG    . SER A 1 368 ? 8.31884   -19.29460 13.43216 1.000 86.20544  ? 263  SER A OG    1 
ATOM   4876 H  H     . SER A 1 368 ? 6.83132   -17.08832 14.93996 1.000 93.20542  ? 263  SER A H     1 
ATOM   4877 H  HA    . SER A 1 368 ? 9.21027   -18.12104 15.39581 1.000 89.98895  ? 263  SER A HA    1 
ATOM   4878 H  HB2   . SER A 1 368 ? 7.85307   -17.42893 13.05501 1.000 91.16058  ? 263  SER A HB2   1 
ATOM   4879 H  HB3   . SER A 1 368 ? 9.40948   -17.73602 12.96178 1.000 91.16058  ? 263  SER A HB3   1 
ATOM   4880 H  HG    . SER A 1 368 ? 8.27336   -19.56269 12.63739 1.000 103.48974 ? 263  SER A HG    1 
ATOM   4881 N  N     . HIS A 1 369 ? 10.93489  -16.38170 15.28176 1.000 65.57504  ? 264  HIS A N     1 
ATOM   4882 C  CA    . HIS A 1 369 ? 11.86049  -15.26342 15.38110 1.000 65.63970  ? 264  HIS A CA    1 
ATOM   4883 C  C     . HIS A 1 369 ? 11.99015  -14.56248 14.03427 1.000 60.54088  ? 264  HIS A C     1 
ATOM   4884 O  O     . HIS A 1 369 ? 11.93308  -15.19019 12.97330 1.000 58.52338  ? 264  HIS A O     1 
ATOM   4885 C  CB    . HIS A 1 369 ? 13.22965  -15.74504 15.85562 1.000 62.36594  ? 264  HIS A CB    1 
ATOM   4886 C  CG    . HIS A 1 369 ? 14.14218  -14.63860 16.28169 1.000 57.50612  ? 264  HIS A CG    1 
ATOM   4887 N  ND1   . HIS A 1 369 ? 14.80704  -13.83360 15.38240 1.000 57.56543  ? 264  HIS A ND1   1 
ATOM   4888 C  CD2   . HIS A 1 369 ? 14.49937  -14.20227 17.51295 1.000 61.34989  ? 264  HIS A CD2   1 
ATOM   4889 C  CE1   . HIS A 1 369 ? 15.53553  -12.94962 16.04086 1.000 55.22186  ? 264  HIS A CE1   1 
ATOM   4890 N  NE2   . HIS A 1 369 ? 15.36678  -13.15186 17.33536 1.000 55.23579  ? 264  HIS A NE2   1 
ATOM   4891 H  H     . HIS A 1 369 ? 11.27523  -17.14772 15.47407 1.000 78.73326  ? 264  HIS A H     1 
ATOM   4892 H  HA    . HIS A 1 369 ? 11.52680  -14.62346 16.02918 1.000 78.81085  ? 264  HIS A HA    1 
ATOM   4893 H  HB2   . HIS A 1 369 ? 13.10663  -16.33643 16.61458 1.000 74.88235  ? 264  HIS A HB2   1 
ATOM   4894 H  HB3   . HIS A 1 369 ? 13.66139  -16.22220 15.12979 1.000 74.88235  ? 264  HIS A HB3   1 
ATOM   4895 H  HD1   . HIS A 1 369 ? 14.75581  -13.89672 14.52625 1.000 69.12174  ? 264  HIS A HD1   1 
ATOM   4896 H  HD2   . HIS A 1 369 ? 14.21136  -14.54885 18.32648 1.000 73.66309  ? 264  HIS A HD2   1 
ATOM   4897 H  HE1   . HIS A 1 369 ? 16.07532  -12.29615 15.65809 1.000 66.30945  ? 264  HIS A HE1   1 
ATOM   4898 H  HE2   . HIS A 1 369 ? 15.73940  -12.69943 17.96470 1.000 66.32616  ? 264  HIS A HE2   1 
ATOM   4899 N  N     . ALA A 1 370 ? 12.15985  -13.24622 14.08661 1.000 59.54690  ? 265  ALA A N     1 
ATOM   4900 C  CA    . ALA A 1 370 ? 12.30108  -12.46693 12.86618 1.000 52.50233  ? 265  ALA A CA    1 
ATOM   4901 C  C     . ALA A 1 370 ? 13.44163  -13.03350 12.02259 1.000 51.47805  ? 265  ALA A C     1 
ATOM   4902 O  O     . ALA A 1 370 ? 14.51404  -13.34205 12.55909 1.000 51.54818  ? 265  ALA A O     1 
ATOM   4903 C  CB    . ALA A 1 370 ? 12.56302  -10.99684 13.20259 1.000 55.11716  ? 265  ALA A CB    1 
ATOM   4904 H  H     . ALA A 1 370 ? 12.19644  -12.78411 14.81098 1.000 71.49949  ? 265  ALA A H     1 
ATOM   4905 H  HA    . ALA A 1 370 ? 11.48259  -12.51473 12.34783 1.000 63.04602  ? 265  ALA A HA    1 
ATOM   4906 H  HB1   . ALA A 1 370 ? 12.67829  -10.49978 12.37763 1.000 66.18381  ? 265  ALA A HB1   1 
ATOM   4907 H  HB2   . ALA A 1 370 ? 11.80570  -10.64621 13.69697 1.000 66.18381  ? 265  ALA A HB2   1 
ATOM   4908 H  HB3   . ALA A 1 370 ? 13.36722  -10.93461 13.74138 1.000 66.18381  ? 265  ALA A HB3   1 
ATOM   4909 N  N     . PRO A 1 371 ? 13.25507  -13.18271 10.71046 1.000 57.28923  ? 266  PRO A N     1 
ATOM   4910 C  CA    . PRO A 1 371 ? 14.28306  -13.83437 9.89169  1.000 59.86791  ? 266  PRO A CA    1 
ATOM   4911 C  C     . PRO A 1 371 ? 15.59943  -13.07280 9.91262  1.000 58.27699  ? 266  PRO A C     1 
ATOM   4912 O  O     . PRO A 1 371 ? 15.65619  -11.86870 10.17053 1.000 59.29142  ? 266  PRO A O     1 
ATOM   4913 C  CB    . PRO A 1 371 ? 13.66666  -13.84816 8.48626  1.000 63.34197  ? 266  PRO A CB    1 
ATOM   4914 C  CG    . PRO A 1 371 ? 12.65479  -12.75863 8.50042  1.000 64.72749  ? 266  PRO A CG    1 
ATOM   4915 C  CD    . PRO A 1 371 ? 12.11479  -12.72074 9.89902  1.000 63.08753  ? 266  PRO A CD    1 
ATOM   4916 H  HA    . PRO A 1 371 ? 14.43309  -14.74324 10.19558 1.000 71.88471  ? 266  PRO A HA    1 
ATOM   4917 H  HB2   . PRO A 1 371 ? 14.35304  -13.67609 7.82281  1.000 76.05358  ? 266  PRO A HB2   1 
ATOM   4918 H  HB3   . PRO A 1 371 ? 13.24953  -14.70737 8.31692  1.000 76.05358  ? 266  PRO A HB3   1 
ATOM   4919 H  HG2   . PRO A 1 371 ? 13.07781  -11.91605 8.27237  1.000 77.71620  ? 266  PRO A HG2   1 
ATOM   4920 H  HG3   . PRO A 1 371 ? 11.94964  -12.95851 7.86503  1.000 77.71620  ? 266  PRO A HG3   1 
ATOM   4921 H  HD2   . PRO A 1 371 ? 11.85733  -11.81876 10.14609 1.000 75.74826  ? 266  PRO A HD2   1 
ATOM   4922 H  HD3   . PRO A 1 371 ? 11.35764  -13.31960 9.99382  1.000 75.74826  ? 266  PRO A HD3   1 
ATOM   4923 N  N     . LEU A 1 372 ? 16.67459  -13.80618 9.61791  1.000 62.24498  ? 267  LEU A N     1 
ATOM   4924 C  CA    . LEU A 1 372 ? 18.01524  -13.24219 9.73489  1.000 64.16720  ? 267  LEU A CA    1 
ATOM   4925 C  C     . LEU A 1 372 ? 18.20348  -12.05167 8.80332  1.000 60.90843  ? 267  LEU A C     1 
ATOM   4926 O  O     . LEU A 1 372 ? 18.83099  -11.05513 9.18055  1.000 62.15536  ? 267  LEU A O     1 
ATOM   4927 C  CB    . LEU A 1 372 ? 19.05618  -14.32366 9.44519  1.000 65.59480  ? 267  LEU A CB    1 
ATOM   4928 C  CG    . LEU A 1 372 ? 20.51574  -13.99259 9.75924  1.000 72.30304  ? 267  LEU A CG    1 
ATOM   4929 C  CD1   . LEU A 1 372 ? 20.69785  -13.61637 11.22342 1.000 74.02613  ? 267  LEU A CD1   1 
ATOM   4930 C  CD2   . LEU A 1 372 ? 21.39981  -15.17572 9.39972  1.000 74.86198  ? 267  LEU A CD2   1 
ATOM   4931 H  H     . LEU A 1 372 ? 16.65396  -14.62350 9.35114  1.000 74.73719  ? 267  LEU A H     1 
ATOM   4932 H  HA    . LEU A 1 372 ? 18.14582  -12.92836 10.64338 1.000 77.04385  ? 267  LEU A HA    1 
ATOM   4933 H  HB2   . LEU A 1 372 ? 18.82567  -15.10650 9.96953  1.000 78.75697  ? 267  LEU A HB2   1 
ATOM   4934 H  HB3   . LEU A 1 372 ? 19.01202  -14.53325 8.49913  1.000 78.75697  ? 267  LEU A HB3   1 
ATOM   4935 H  HG    . LEU A 1 372 ? 20.78468  -13.22557 9.22985  1.000 86.80686  ? 267  LEU A HG    1 
ATOM   4936 H  HD11  . LEU A 1 372 ? 21.64566  -13.53550 11.41317 1.000 88.87457  ? 267  LEU A HD11  1 
ATOM   4937 H  HD12  . LEU A 1 372 ? 20.25385  -12.77012 11.38962 1.000 88.87457  ? 267  LEU A HD12  1 
ATOM   4938 H  HD13  . LEU A 1 372 ? 20.30734  -14.30942 11.77848 1.000 88.87457  ? 267  LEU A HD13  1 
ATOM   4939 H  HD21  . LEU A 1 372 ? 22.32093  -14.95749 9.61141  1.000 89.87759  ? 267  LEU A HD21  1 
ATOM   4940 H  HD22  . LEU A 1 372 ? 21.11676  -15.94882 9.91265  1.000 89.87759  ? 267  LEU A HD22  1 
ATOM   4941 H  HD23  . LEU A 1 372 ? 21.31274  -15.35824 8.45104  1.000 89.87759  ? 267  LEU A HD23  1 
ATOM   4942 N  N     . TRP A 1 373 ? 17.67217  -12.13282 7.58043  1.000 66.29253  ? 268  TRP A N     1 
ATOM   4943 C  CA    . TRP A 1 373 ? 17.82190  -11.01986 6.64746  1.000 63.68134  ? 268  TRP A CA    1 
ATOM   4944 C  C     . TRP A 1 373 ? 17.11786  -9.77261  7.16699  1.000 59.13917  ? 268  TRP A C     1 
ATOM   4945 O  O     . TRP A 1 373 ? 17.61114  -8.65225  6.98786  1.000 59.25983  ? 268  TRP A O     1 
ATOM   4946 C  CB    . TRP A 1 373 ? 17.28743  -11.40347 5.26566  1.000 72.14304  ? 268  TRP A CB    1 
ATOM   4947 C  CG    . TRP A 1 373 ? 15.80380  -11.62764 5.21075  1.000 66.25089  ? 268  TRP A CG    1 
ATOM   4948 C  CD1   . TRP A 1 373 ? 15.15235  -12.82096 5.32228  1.000 65.35240  ? 268  TRP A CD1   1 
ATOM   4949 C  CD2   . TRP A 1 373 ? 14.78822  -10.63251 5.02139  1.000 68.33184  ? 268  TRP A CD2   1 
ATOM   4950 N  NE1   . TRP A 1 373 ? 13.79579  -12.63163 5.21846  1.000 68.50340  ? 268  TRP A NE1   1 
ATOM   4951 C  CE2   . TRP A 1 373 ? 13.54582  -11.29718 5.03421  1.000 69.42256  ? 268  TRP A CE2   1 
ATOM   4952 C  CE3   . TRP A 1 373 ? 14.80905  -9.24481  4.84581  1.000 70.22001  ? 268  TRP A CE3   1 
ATOM   4953 C  CZ2   . TRP A 1 373 ? 12.33560  -10.62303 4.87668  1.000 76.19217  ? 268  TRP A CZ2   1 
ATOM   4954 C  CZ3   . TRP A 1 373 ? 13.60498  -8.57625  4.69024  1.000 72.81080  ? 268  TRP A CZ3   1 
ATOM   4955 C  CH2   . TRP A 1 373 ? 12.38600  -9.26667  4.70630  1.000 76.40397  ? 268  TRP A CH2   1 
ATOM   4956 H  H     . TRP A 1 373 ? 17.23144  -12.80535 7.27537  1.000 79.59426  ? 268  TRP A H     1 
ATOM   4957 H  HA    . TRP A 1 373 ? 18.76623  -10.81958 6.55243  1.000 76.46082  ? 268  TRP A HA    1 
ATOM   4958 H  HB2   . TRP A 1 373 ? 17.49871  -10.68971 4.64372  1.000 86.61487  ? 268  TRP A HB2   1 
ATOM   4959 H  HB3   . TRP A 1 373 ? 17.71821  -12.22611 4.98534  1.000 86.61487  ? 268  TRP A HB3   1 
ATOM   4960 H  HD1   . TRP A 1 373 ? 15.56671  -13.64367 5.45011  1.000 78.46610  ? 268  TRP A HD1   1 
ATOM   4961 H  HE1   . TRP A 1 373 ? 13.20005  -13.25033 5.26204  1.000 82.24730  ? 268  TRP A HE1   1 
ATOM   4962 H  HE3   . TRP A 1 373 ? 15.61460  -8.78023  4.83373  1.000 84.30723  ? 268  TRP A HE3   1 
ATOM   4963 H  HZ2   . TRP A 1 373 ? 11.52471  -11.07828 4.88704  1.000 91.47382  ? 268  TRP A HZ2   1 
ATOM   4964 H  HZ3   . TRP A 1 373 ? 13.60623  -7.65364  4.57319  1.000 87.41617  ? 268  TRP A HZ3   1 
ATOM   4965 H  HH2   . TRP A 1 373 ? 11.59338  -8.79225  4.59873  1.000 91.72798  ? 268  TRP A HH2   1 
ATOM   4966 N  N     . LEU A 1 374 ? 15.96320  -9.94512  7.81647  1.000 56.04738  ? 269  LEU A N     1 
ATOM   4967 C  CA    . LEU A 1 374 ? 15.26981  -8.79812  8.39363  1.000 61.44537  ? 269  LEU A CA    1 
ATOM   4968 C  C     . LEU A 1 374 ? 16.03617  -8.23876  9.58618  1.000 59.27698  ? 269  LEU A C     1 
ATOM   4969 O  O     . LEU A 1 374 ? 16.07547  -7.01945  9.78924  1.000 51.59311  ? 269  LEU A O     1 
ATOM   4970 C  CB    . LEU A 1 374 ? 13.85131  -9.19058  8.80522  1.000 65.38049  ? 269  LEU A CB    1 
ATOM   4971 C  CG    . LEU A 1 374 ? 13.00741  -8.06692  9.41562  1.000 65.05228  ? 269  LEU A CG    1 
ATOM   4972 C  CD1   . LEU A 1 374 ? 12.81196  -6.92240  8.42414  1.000 64.68072  ? 269  LEU A CD1   1 
ATOM   4973 C  CD2   . LEU A 1 374 ? 11.66496  -8.60518  9.89285  1.000 66.42616  ? 269  LEU A CD2   1 
ATOM   4974 H  H     . LEU A 1 374 ? 15.56997  -10.70097 7.93334  1.000 67.30008  ? 269  LEU A H     1 
ATOM   4975 H  HA    . LEU A 1 374 ? 15.20329  -8.10238  7.72100  1.000 73.77766  ? 269  LEU A HA    1 
ATOM   4976 H  HB2   . LEU A 1 374 ? 13.38299  -9.50917  8.01777  1.000 78.49981  ? 269  LEU A HB2   1 
ATOM   4977 H  HB3   . LEU A 1 374 ? 13.91081  -9.89901  9.46513  1.000 78.49981  ? 269  LEU A HB3   1 
ATOM   4978 H  HG    . LEU A 1 374 ? 13.47868  -7.70836  10.18389 1.000 78.10595  ? 269  LEU A HG    1 
ATOM   4979 H  HD11  . LEU A 1 374 ? 12.21010  -6.26796  8.81192  1.000 77.66007  ? 269  LEU A HD11  1 
ATOM   4980 H  HD12  . LEU A 1 374 ? 13.67204  -6.51306  8.24081  1.000 77.66007  ? 269  LEU A HD12  1 
ATOM   4981 H  HD13  . LEU A 1 374 ? 12.43247  -7.27599  7.60447  1.000 77.66007  ? 269  LEU A HD13  1 
ATOM   4982 H  HD21  . LEU A 1 374 ? 11.14020  -7.87229  10.25116 1.000 79.75461  ? 269  LEU A HD21  1 
ATOM   4983 H  HD22  . LEU A 1 374 ? 11.20126  -9.00793  9.14206  1.000 79.75461  ? 269  LEU A HD22  1 
ATOM   4984 H  HD23  . LEU A 1 374 ? 11.81835  -9.27016  10.58218 1.000 79.75461  ? 269  LEU A HD23  1 
ATOM   4985 N  N     . MET A 1 375 ? 16.64336  -9.11515  10.39076 1.000 58.94064  ? 270  MET A N     1 
ATOM   4986 C  CA    . MET A 1 375 ? 17.47226  -8.65277  11.49838 1.000 56.65493  ? 270  MET A CA    1 
ATOM   4987 C  C     . MET A 1 375 ? 18.56805  -7.71968  10.99978 1.000 59.23961  ? 270  MET A C     1 
ATOM   4988 O  O     . MET A 1 375 ? 18.73182  -6.60298  11.50676 1.000 54.38330  ? 270  MET A O     1 
ATOM   4989 C  CB    . MET A 1 375 ? 18.08578  -9.84598  12.23204 1.000 57.08784  ? 270  MET A CB    1 
ATOM   4990 C  CG    . MET A 1 375 ? 17.09049  -10.73987 12.95469 1.000 56.37924  ? 270  MET A CG    1 
ATOM   4991 S  SD    . MET A 1 375 ? 16.13751  -9.93451  14.26338 1.000 58.52733  ? 270  MET A SD    1 
ATOM   4992 C  CE    . MET A 1 375 ? 17.28729  -8.71743  14.90395 1.000 53.42976  ? 270  MET A CE    1 
ATOM   4993 H  H     . MET A 1 375 ? 16.59078  -9.97027  10.31588 1.000 70.77199  ? 270  MET A H     1 
ATOM   4994 H  HA    . MET A 1 375 ? 16.90738  -8.17589  12.12639 1.000 68.02913  ? 270  MET A HA    1 
ATOM   4995 H  HB2   . MET A 1 375 ? 18.55370  -10.39634 11.58469 1.000 68.54862  ? 270  MET A HB2   1 
ATOM   4996 H  HB3   . MET A 1 375 ? 18.70953  -9.51062  12.89489 1.000 68.54862  ? 270  MET A HB3   1 
ATOM   4997 H  HG2   . MET A 1 375 ? 16.45716  -11.08152 12.30425 1.000 67.69830  ? 270  MET A HG2   1 
ATOM   4998 H  HG3   . MET A 1 375 ? 17.57705  -11.47394 13.36125 1.000 67.69830  ? 270  MET A HG3   1 
ATOM   4999 H  HE1   . MET A 1 375 ? 16.89881  -8.29760  15.68736 1.000 64.15893  ? 270  MET A HE1   1 
ATOM   5000 H  HE2   . MET A 1 375 ? 18.11606  -9.16110  15.14312 1.000 64.15893  ? 270  MET A HE2   1 
ATOM   5001 H  HE3   . MET A 1 375 ? 17.45465  -8.05037  14.21990 1.000 64.15893  ? 270  MET A HE3   1 
ATOM   5002 N  N     . TYR A 1 376 ? 19.32814  -8.16215  9.99535  1.000 55.17282  ? 271  TYR A N     1 
ATOM   5003 C  CA    . TYR A 1 376 ? 20.42835  -7.34693  9.49549  1.000 59.75852  ? 271  TYR A CA    1 
ATOM   5004 C  C     . TYR A 1 376 ? 19.92355  -6.10290  8.77626  1.000 53.25382  ? 271  TYR A C     1 
ATOM   5005 O  O     . TYR A 1 376 ? 20.59187  -5.06513  8.80191  1.000 50.06988  ? 271  TYR A O     1 
ATOM   5006 C  CB    . TYR A 1 376 ? 21.32055  -8.18240  8.57862  1.000 61.95241  ? 271  TYR A CB    1 
ATOM   5007 C  CG    . TYR A 1 376 ? 22.17091  -9.20036  9.31435  1.000 64.23991  ? 271  TYR A CG    1 
ATOM   5008 C  CD1   . TYR A 1 376 ? 22.81646  -10.21990 8.62947  1.000 68.47337  ? 271  TYR A CD1   1 
ATOM   5009 C  CD2   . TYR A 1 376 ? 22.33245  -9.13874  10.69348 1.000 63.68729  ? 271  TYR A CD2   1 
ATOM   5010 C  CE1   . TYR A 1 376 ? 23.59668  -11.14637 9.29747  1.000 67.47320  ? 271  TYR A CE1   1 
ATOM   5011 C  CE2   . TYR A 1 376 ? 23.10906  -10.06128 11.36666 1.000 70.45538  ? 271  TYR A CE2   1 
ATOM   5012 C  CZ    . TYR A 1 376 ? 23.73856  -11.06416 10.66193 1.000 71.24367  ? 271  TYR A CZ    1 
ATOM   5013 O  OH    . TYR A 1 376 ? 24.51603  -11.98824 11.32129 1.000 71.99768  ? 271  TYR A OH    1 
ATOM   5014 H  H     . TYR A 1 376 ? 19.22773  -8.91673  9.59520  1.000 66.25060  ? 271  TYR A H     1 
ATOM   5015 H  HA    . TYR A 1 376 ? 20.96951  -7.05177  10.24444 1.000 71.75344  ? 271  TYR A HA    1 
ATOM   5016 N  N     . LEU A 1 377 ? 18.75056  -6.17573  8.14560  1.000 56.22292  ? 272  LEU A N     1 
ATOM   5017 C  CA    . LEU A 1 377 ? 18.16260  -4.97334  7.56504  1.000 58.11778  ? 272  LEU A CA    1 
ATOM   5018 C  C     . LEU A 1 377 ? 17.88304  -3.93322  8.64217  1.000 51.42177  ? 272  LEU A C     1 
ATOM   5019 O  O     . LEU A 1 377 ? 18.14309  -2.74004  8.44803  1.000 54.65055  ? 272  LEU A O     1 
ATOM   5020 C  CB    . LEU A 1 377 ? 16.87849  -5.32504  6.81544  1.000 65.84926  ? 272  LEU A CB    1 
ATOM   5021 C  CG    . LEU A 1 377 ? 16.24758  -4.18954  6.00701  1.000 62.85412  ? 272  LEU A CG    1 
ATOM   5022 C  CD1   . LEU A 1 377 ? 17.15987  -3.76305  4.86653  1.000 57.71753  ? 272  LEU A CD1   1 
ATOM   5023 C  CD2   . LEU A 1 377 ? 14.88713  -4.61111  5.48014  1.000 77.41890  ? 272  LEU A CD2   1 
ATOM   5024 H  H     . LEU A 1 377 ? 18.28671  -6.89263  8.04310  1.000 67.51072  ? 272  LEU A H     1 
ATOM   5025 H  HA    . LEU A 1 377 ? 18.78630  -4.59336  6.92667  1.000 69.78456  ? 272  LEU A HA    1 
ATOM   5026 H  HB2   . LEU A 1 377 ? 17.07649  -6.04450  6.19569  1.000 79.06233  ? 272  LEU A HB2   1 
ATOM   5027 H  HB3   . LEU A 1 377 ? 16.21926  -5.61783  7.46398  1.000 79.06233  ? 272  LEU A HB3   1 
ATOM   5028 H  HG    . LEU A 1 377 ? 16.12383  -3.42114  6.58592  1.000 75.46815  ? 272  LEU A HG    1 
ATOM   5029 H  HD11  . LEU A 1 377 ? 16.69711  -3.10910  4.31962  1.000 69.30425  ? 272  LEU A HD11  1 
ATOM   5030 H  HD12  . LEU A 1 377 ? 17.96703  -3.37283  5.23682  1.000 69.30425  ? 272  LEU A HD12  1 
ATOM   5031 H  HD13  . LEU A 1 377 ? 17.38353  -4.54164  4.33299  1.000 69.30425  ? 272  LEU A HD13  1 
ATOM   5032 H  HD21  . LEU A 1 377 ? 14.48535  -3.86407  5.00961  1.000 92.94590  ? 272  LEU A HD21  1 
ATOM   5033 H  HD22  . LEU A 1 377 ? 15.00122  -5.36048  4.87489  1.000 92.94590  ? 272  LEU A HD22  1 
ATOM   5034 H  HD23  . LEU A 1 377 ? 14.32606  -4.87180  6.22724  1.000 92.94590  ? 272  LEU A HD23  1 
ATOM   5035 N  N     . ALA A 1 378 ? 17.35739  -4.36977  9.78962  1.000 51.51179  ? 273  ALA A N     1 
ATOM   5036 C  CA    . ALA A 1 378 ? 17.08614  -3.44141  10.88255 1.000 52.82486  ? 273  ALA A CA    1 
ATOM   5037 C  C     . ALA A 1 378 ? 18.37638  -2.89409  11.48255 1.000 51.34099  ? 273  ALA A C     1 
ATOM   5038 O  O     . ALA A 1 378 ? 18.45214  -1.70945  11.82764 1.000 49.66528  ? 273  ALA A O     1 
ATOM   5039 C  CB    . ALA A 1 378 ? 16.25105  -4.13159  11.96097 1.000 52.75707  ? 273  ALA A CB    1 
ATOM   5040 H  H     . ALA A 1 378 ? 17.15200  -5.18797  9.95681  1.000 61.85737  ? 273  ALA A H     1 
ATOM   5041 H  HA    . ALA A 1 378 ? 16.57575  -2.69413  10.53331 1.000 63.43304  ? 273  ALA A HA    1 
ATOM   5042 H  HB1   . ALA A 1 378 ? 16.07561  -3.50066  12.67654 1.000 63.35170  ? 273  ALA A HB1   1 
ATOM   5043 H  HB2   . ALA A 1 378 ? 15.41472  -4.42958  11.57027 1.000 63.35170  ? 273  ALA A HB2   1 
ATOM   5044 H  HB3   . ALA A 1 378 ? 16.74527  -4.89229  12.30447 1.000 63.35170  ? 273  ALA A HB3   1 
ATOM   5045 N  N     . ILE A 1 379 ? 19.39487  -3.74314  11.63423 1.000 52.76314  ? 274  ILE A N     1 
ATOM   5046 C  CA    . ILE A 1 379 ? 20.68391  -3.27223  12.13530 1.000 53.02229  ? 274  ILE A CA    1 
ATOM   5047 C  C     . ILE A 1 379 ? 21.27324  -2.24753  11.17565 1.000 50.65258  ? 274  ILE A C     1 
ATOM   5048 O  O     . ILE A 1 379 ? 21.75676  -1.18493  11.58622 1.000 47.50310  ? 274  ILE A O     1 
ATOM   5049 C  CB    . ILE A 1 379 ? 21.64296  -4.45778  12.34792 1.000 55.33554  ? 274  ILE A CB    1 
ATOM   5050 C  CG1   . ILE A 1 379 ? 21.11767  -5.37601  13.45307 1.000 52.95071  ? 274  ILE A CG1   1 
ATOM   5051 C  CG2   . ILE A 1 379 ? 23.04621  -3.95788  12.68635 1.000 51.94445  ? 274  ILE A CG2   1 
ATOM   5052 C  CD1   . ILE A 1 379 ? 21.76473  -6.74218  13.46954 1.000 53.39733  ? 274  ILE A CD1   1 
ATOM   5053 H  H     . ILE A 1 379 ? 19.36508  -4.58407  11.45665 1.000 63.35899  ? 274  ILE A H     1 
ATOM   5054 H  HA    . ILE A 1 379 ? 20.54532  -2.84121  12.99315 1.000 63.66996  ? 274  ILE A HA    1 
ATOM   5055 H  HB    . ILE A 1 379 ? 21.68907  -4.96506  11.52243 1.000 66.44587  ? 274  ILE A HB    1 
ATOM   5056 H  HG12  . ILE A 1 379 ? 21.28653  -4.95821  14.31204 1.000 63.58407  ? 274  ILE A HG12  1 
ATOM   5057 H  HG13  . ILE A 1 379 ? 20.16414  -5.50169  13.32701 1.000 63.58407  ? 274  ILE A HG13  1 
ATOM   5058 H  HG21  . ILE A 1 379 ? 23.57969  -4.70400  13.00195 1.000 62.37656  ? 274  ILE A HG21  1 
ATOM   5059 H  HG22  . ILE A 1 379 ? 23.44722  -3.57851  11.88875 1.000 62.37656  ? 274  ILE A HG22  1 
ATOM   5060 H  HG23  . ILE A 1 379 ? 22.98203  -3.28108  13.37826 1.000 62.37656  ? 274  ILE A HG23  1 
ATOM   5061 H  HD11  . ILE A 1 379 ? 21.39999  -7.25549  14.20737 1.000 64.12001  ? 274  ILE A HD11  1 
ATOM   5062 H  HD12  . ILE A 1 379 ? 21.57726  -7.19055  12.63007 1.000 64.12001  ? 274  ILE A HD12  1 
ATOM   5063 H  HD13  . ILE A 1 379 ? 22.72245  -6.63668  13.58152 1.000 64.12001  ? 274  ILE A HD13  1 
ATOM   5064 N  N     . VAL A 1 380 ? 21.24017  -2.55615  9.87684  1.000 51.30347  ? 275  VAL A N     1 
ATOM   5065 C  CA    . VAL A 1 380 ? 21.77820  -1.64321  8.87362  1.000 49.77950  ? 275  VAL A CA    1 
ATOM   5066 C  C     . VAL A 1 380 ? 21.02943  -0.31996  8.90095  1.000 50.73152  ? 275  VAL A C     1 
ATOM   5067 O  O     . VAL A 1 380 ? 21.61926  0.74572   8.67322  1.000 49.35280  ? 275  VAL A O     1 
ATOM   5068 C  CB    . VAL A 1 380 ? 21.71657  -2.31033  7.48374  1.000 54.11568  ? 275  VAL A CB    1 
ATOM   5069 C  CG1   . VAL A 1 380 ? 21.96495  -1.29630  6.38802  1.000 58.61131  ? 275  VAL A CG1   1 
ATOM   5070 C  CG2   . VAL A 1 380 ? 22.73453  -3.43767  7.39890  1.000 50.68093  ? 275  VAL A CG2   1 
ATOM   5071 H  H     . VAL A 1 380 ? 20.91344  -3.28344  9.55451  1.000 61.60738  ? 275  VAL A H     1 
ATOM   5072 H  HA    . VAL A 1 380 ? 22.70794  -1.45602  9.07719  1.000 59.77862  ? 275  VAL A HA    1 
ATOM   5073 H  HB    . VAL A 1 380 ? 20.82929  -2.68038  7.35453  1.000 64.98203  ? 275  VAL A HB    1 
ATOM   5074 H  HG11  . VAL A 1 380 ? 22.08440  -1.76361  5.54644  1.000 70.37679  ? 275  VAL A HG11  1 
ATOM   5075 H  HG12  . VAL A 1 380 ? 21.20165  -0.70055  6.33013  1.000 70.37679  ? 275  VAL A HG12  1 
ATOM   5076 H  HG13  . VAL A 1 380 ? 22.76429  -0.78998  6.60158  1.000 70.37679  ? 275  VAL A HG13  1 
ATOM   5077 H  HG21  . VAL A 1 380 ? 22.60144  -3.92154  6.56880  1.000 60.86033  ? 275  VAL A HG21  1 
ATOM   5078 H  HG22  . VAL A 1 380 ? 23.62741  -3.05931  7.42171  1.000 60.86033  ? 275  VAL A HG22  1 
ATOM   5079 H  HG23  . VAL A 1 380 ? 22.60870  -4.03423  8.15334  1.000 60.86033  ? 275  VAL A HG23  1 
ATOM   5080 N  N     . LEU A 1 381 ? 19.72941  -0.35694  9.18594  1.000 45.74286  ? 276  LEU A N     1 
ATOM   5081 C  CA    . LEU A 1 381 ? 18.95051  0.87426   9.25286  1.000 48.12847  ? 276  LEU A CA    1 
ATOM   5082 C  C     . LEU A 1 381 ? 19.35391  1.71667   10.45774 1.000 47.92404  ? 276  LEU A C     1 
ATOM   5083 O  O     . LEU A 1 381 ? 19.58752  2.92449   10.33284 1.000 52.63346  ? 276  LEU A O     1 
ATOM   5084 C  CB    . LEU A 1 381 ? 17.46170  0.54099   9.30204  1.000 51.48780  ? 276  LEU A CB    1 
ATOM   5085 C  CG    . LEU A 1 381 ? 16.51544  1.72871   9.46844  1.000 55.10525  ? 276  LEU A CG    1 
ATOM   5086 C  CD1   . LEU A 1 381 ? 16.71143  2.74748   8.35884  1.000 54.47844  ? 276  LEU A CD1   1 
ATOM   5087 C  CD2   . LEU A 1 381 ? 15.07933  1.23726   9.49669  1.000 59.21822  ? 276  LEU A CD2   1 
ATOM   5088 H  H     . LEU A 1 381 ? 19.28025  -1.07338  9.34269  1.000 54.93465  ? 276  LEU A H     1 
ATOM   5089 H  HA    . LEU A 1 381 ? 19.11906  1.39722   8.45348  1.000 57.79738  ? 276  LEU A HA    1 
ATOM   5090 H  HB2   . LEU A 1 381 ? 17.22337  0.09774   8.47280  1.000 61.82857  ? 276  LEU A HB2   1 
ATOM   5091 H  HB3   . LEU A 1 381 ? 17.30969  -0.05478  10.05226 1.000 61.82857  ? 276  LEU A HB3   1 
ATOM   5092 H  HG    . LEU A 1 381 ? 16.71050  2.17595   10.30679 1.000 66.16952  ? 276  LEU A HG    1 
ATOM   5093 H  HD11  . LEU A 1 381 ? 16.05419  3.45382   8.45894  1.000 65.41734  ? 276  LEU A HD11  1 
ATOM   5094 H  HD12  . LEU A 1 381 ? 17.60613  3.11658   8.42342  1.000 65.41734  ? 276  LEU A HD12  1 
ATOM   5095 H  HD13  . LEU A 1 381 ? 16.59619  2.30742   7.50212  1.000 65.41734  ? 276  LEU A HD13  1 
ATOM   5096 H  HD21  . LEU A 1 381 ? 14.50896  1.94757   9.82992  1.000 71.10508  ? 276  LEU A HD21  1 
ATOM   5097 H  HD22  . LEU A 1 381 ? 14.81153  0.99255   8.59708  1.000 71.10508  ? 276  LEU A HD22  1 
ATOM   5098 H  HD23  . LEU A 1 381 ? 15.02127  0.46495   10.08071 1.000 71.10508  ? 276  LEU A HD23  1 
ATOM   5099 N  N     . ALA A 1 382 ? 19.42368  1.10043   11.63980 1.000 45.44719  ? 277  ALA A N     1 
ATOM   5100 C  CA    . ALA A 1 382 ? 19.89610  1.82102   12.81645 1.000 44.78654  ? 277  ALA A CA    1 
ATOM   5101 C  C     . ALA A 1 382 ? 21.24457  2.47766   12.54857 1.000 49.70656  ? 277  ALA A C     1 
ATOM   5102 O  O     . ALA A 1 382 ? 21.46714  3.63678   12.91920 1.000 46.70448  ? 277  ALA A O     1 
ATOM   5103 C  CB    . ALA A 1 382 ? 19.99106  0.86984   14.00942 1.000 45.83073  ? 277  ALA A CB    1 
ATOM   5104 H  H     . ALA A 1 382 ? 19.20692  0.28053   11.78254 1.000 54.57985  ? 277  ALA A H     1 
ATOM   5105 H  HA    . ALA A 1 382 ? 19.25803  2.51681   13.03927 1.000 53.78707  ? 277  ALA A HA    1 
ATOM   5106 H  HB1   . ALA A 1 382 ? 20.30617  1.36353   14.78264 1.000 55.04009  ? 277  ALA A HB1   1 
ATOM   5107 H  HB2   . ALA A 1 382 ? 19.11263  0.49961   14.18883 1.000 55.04009  ? 277  ALA A HB2   1 
ATOM   5108 H  HB3   . ALA A 1 382 ? 20.61324  0.15689   13.79612 1.000 55.04009  ? 277  ALA A HB3   1 
ATOM   5109 N  N     . HIS A 1 383 ? 22.15558  1.75159   11.89381 1.000 49.63532  ? 278  HIS A N     1 
ATOM   5110 C  CA    . HIS A 1 383 ? 23.46231  2.31650   11.57226 1.000 47.83585  ? 278  HIS A CA    1 
ATOM   5111 C  C     . HIS A 1 383 ? 23.34200  3.44870   10.55809 1.000 51.71277  ? 278  HIS A C     1 
ATOM   5112 O  O     . HIS A 1 383 ? 24.06896  4.44597   10.64529 1.000 47.14861  ? 278  HIS A O     1 
ATOM   5113 C  CB    . HIS A 1 383 ? 24.38865  1.21929   11.04815 1.000 45.91590  ? 278  HIS A CB    1 
ATOM   5114 C  CG    . HIS A 1 383 ? 24.74318  0.18752   12.07390 1.000 48.47620  ? 278  HIS A CG    1 
ATOM   5115 N  ND1   . HIS A 1 383 ? 25.48701  -0.93362  11.77607 1.000 46.69454  ? 278  HIS A ND1   1 
ATOM   5116 C  CD2   . HIS A 1 383 ? 24.45986  0.11022   13.39582 1.000 43.83044  ? 278  HIS A CD2   1 
ATOM   5117 C  CE1   . HIS A 1 383 ? 25.64543  -1.65755  12.86962 1.000 47.15287  ? 278  HIS A CE1   1 
ATOM   5118 N  NE2   . HIS A 1 383 ? 25.03288  -1.04576  13.86677 1.000 43.19735  ? 278  HIS A NE2   1 
ATOM   5119 H  H     . HIS A 1 383 ? 22.04157  0.94127   11.62927 1.000 59.60559  ? 278  HIS A H     1 
ATOM   5120 H  HA    . HIS A 1 383 ? 23.85435  2.68132   12.38103 1.000 57.44624  ? 278  HIS A HA    1 
ATOM   5121 H  HB2   . HIS A 1 383 ? 23.94939  0.76580   10.31174 1.000 55.14230  ? 278  HIS A HB2   1 
ATOM   5122 H  HB3   . HIS A 1 383 ? 25.21344  1.62761   10.74171 1.000 55.14230  ? 278  HIS A HB3   1 
ATOM   5123 H  HD1   . HIS A 1 383 ? 25.79933  -1.13117  10.99952 1.000 56.07667  ? 278  HIS A HD1   1 
ATOM   5124 H  HD2   . HIS A 1 383 ? 23.96907  0.72490   13.89200 1.000 52.63975  ? 278  HIS A HD2   1 
ATOM   5125 H  HE1   . HIS A 1 383 ? 26.10948  -2.46143  12.92742 1.000 56.62666  ? 278  HIS A HE1   1 
ATOM   5126 N  N     . THR A 1 384 ? 22.43046  3.31220   9.58860  1.000 48.56907  ? 279  THR A N     1 
ATOM   5127 C  CA    . THR A 1 384 ? 22.21550  4.37313   8.60869  1.000 47.98640  ? 279  THR A CA    1 
ATOM   5128 C  C     . THR A 1 384 ? 21.97232  5.71400   9.28454  1.000 47.93457  ? 279  THR A C     1 
ATOM   5129 O  O     . THR A 1 384 ? 22.32964  6.76280   8.73505  1.000 52.28510  ? 279  THR A O     1 
ATOM   5130 C  CB    . THR A 1 384 ? 21.03254  4.01476   7.69955  1.000 48.69326  ? 279  THR A CB    1 
ATOM   5131 O  OG1   . THR A 1 384 ? 21.45601  3.07190   6.70696  1.000 51.88604  ? 279  THR A OG1   1 
ATOM   5132 C  CG2   . THR A 1 384 ? 20.46692  5.24814   7.00742  1.000 51.96538  ? 279  THR A CG2   1 
ATOM   5133 H  H     . THR A 1 384 ? 21.92997  2.62140   9.47955  1.000 58.32611  ? 279  THR A H     1 
ATOM   5134 H  HA    . THR A 1 384 ? 23.00651  4.45452   8.05318  1.000 57.62689  ? 279  THR A HA    1 
ATOM   5135 H  HB    . THR A 1 384 ? 20.32798  3.62840   8.24289  1.000 58.47513  ? 279  THR A HB    1 
ATOM   5136 H  HG1   . THR A 1 384 ? 20.82642  2.91371   6.17386  1.000 62.30646  ? 279  THR A HG1   1 
ATOM   5137 H  HG21  . THR A 1 384 ? 19.82990  4.98311   6.32561  1.000 62.40167  ? 279  THR A HG21  1 
ATOM   5138 H  HG22  . THR A 1 384 ? 20.01824  5.81501   7.65414  1.000 62.40167  ? 279  THR A HG22  1 
ATOM   5139 H  HG23  . THR A 1 384 ? 21.18304  5.75218   6.59028  1.000 62.40167  ? 279  THR A HG23  1 
ATOM   5140 N  N     . ASN A 1 385 ? 21.37130  5.70164   10.47594 1.000 47.92700  ? 280  ASN A N     1 
ATOM   5141 C  CA    . ASN A 1 385 ? 21.08331  6.95085   11.17148 1.000 52.40278  ? 280  ASN A CA    1 
ATOM   5142 C  C     . ASN A 1 385 ? 22.33426  7.79840   11.35943 1.000 49.97958  ? 280  ASN A C     1 
ATOM   5143 O  O     . ASN A 1 385 ? 22.24281  9.02969   11.43571 1.000 59.37830  ? 280  ASN A O     1 
ATOM   5144 C  CB    . ASN A 1 385 ? 20.44762  6.66266   12.53003 1.000 53.25145  ? 280  ASN A CB    1 
ATOM   5145 C  CG    . ASN A 1 385 ? 20.13666  7.92957   13.30418 1.000 51.72526  ? 280  ASN A CG    1 
ATOM   5146 O  OD1   . ASN A 1 385 ? 20.65653  8.14800   14.39868 1.000 51.18926  ? 280  ASN A OD1   1 
ATOM   5147 N  ND2   . ASN A 1 385 ? 19.29468  8.78157   12.72748 1.000 54.32543  ? 280  ASN A ND2   1 
ATOM   5148 H  H     . ASN A 1 385 ? 21.12429  4.99286   10.89571 1.000 57.55562  ? 280  ASN A H     1 
ATOM   5149 H  HA    . ASN A 1 385 ? 20.45162  7.45705   10.63704 1.000 62.92655  ? 280  ASN A HA    1 
ATOM   5150 H  HB2   . ASN A 1 385 ? 19.61697  6.18008   12.39575 1.000 63.94495  ? 280  ASN A HB2   1 
ATOM   5151 H  HB3   . ASN A 1 385 ? 21.05977  6.12839   13.05989 1.000 63.94495  ? 280  ASN A HB3   1 
ATOM   5152 H  HD21  . ASN A 1 385 ? 19.08552  9.51492   13.12503 1.000 65.23373  ? 280  ASN A HD21  1 
ATOM   5153 H  HD22  . ASN A 1 385 ? 18.95918  8.59937   11.95687 1.000 65.23373  ? 280  ASN A HD22  1 
ATOM   5154 N  N     . SER A 1 386 ? 23.50146  7.16821   11.44537 1.000 46.59226  ? 281  SER A N     1 
ATOM   5155 C  CA    . SER A 1 386 ? 24.75019  7.89203   11.64070 1.000 48.89285  ? 281  SER A CA    1 
ATOM   5156 C  C     . SER A 1 386 ? 25.24873  8.57969   10.37563 1.000 52.58622  ? 281  SER A C     1 
ATOM   5157 O  O     . SER A 1 386 ? 26.31196  9.20963   10.41440 1.000 47.50831  ? 281  SER A O     1 
ATOM   5158 C  CB    . SER A 1 386 ? 25.82437  6.93611   12.16540 1.000 47.47646  ? 281  SER A CB    1 
ATOM   5159 O  OG    . SER A 1 386 ? 25.50421  6.49171   13.47332 1.000 51.96457  ? 281  SER A OG    1 
ATOM   5160 H  H     . SER A 1 386 ? 23.59606  6.31504   11.39302 1.000 55.95393  ? 281  SER A H     1 
ATOM   5161 H  HA    . SER A 1 386 ? 24.60682  8.58112   12.30815 1.000 58.71464  ? 281  SER A HA    1 
ATOM   5162 H  HB2   . SER A 1 386 ? 25.88016  6.16833   11.57523 1.000 57.01497  ? 281  SER A HB2   1 
ATOM   5163 H  HB3   . SER A 1 386 ? 26.67623  7.39946   12.18841 1.000 57.01497  ? 281  SER A HB3   1 
ATOM   5164 H  HG    . SER A 1 386 ? 26.15861  6.08374   13.80636 1.000 62.40070  ? 281  SER A HG    1 
ATOM   5165 N  N     . VAL A 1 387 ? 24.51562  8.48018   9.26786  1.000 52.59052  ? 282  VAL A N     1 
ATOM   5166 C  CA    . VAL A 1 387 ? 24.90534  9.12643   8.02146  1.000 55.13886  ? 282  VAL A CA    1 
ATOM   5167 C  C     . VAL A 1 387 ? 24.02174  10.31921  7.67558  1.000 56.96424  ? 282  VAL A C     1 
ATOM   5168 O  O     . VAL A 1 387 ? 24.47211  11.20372  6.93078  1.000 62.04955  ? 282  VAL A O     1 
ATOM   5169 C  CB    . VAL A 1 387 ? 24.90853  8.11377   6.85470  1.000 59.59053  ? 282  VAL A CB    1 
ATOM   5170 C  CG1   . VAL A 1 387 ? 24.81321  8.81983   5.50434  1.000 55.89637  ? 282  VAL A CG1   1 
ATOM   5171 C  CG2   . VAL A 1 387 ? 26.16066  7.25003   6.90132  1.000 61.13638  ? 282  VAL A CG2   1 
ATOM   5172 H  H     . VAL A 1 387 ? 23.77983  8.03822   9.21417  1.000 63.15184  ? 282  VAL A H     1 
ATOM   5173 H  HA    . VAL A 1 387 ? 25.80876  9.46492   8.12225  1.000 66.20985  ? 282  VAL A HA    1 
ATOM   5174 H  HB    . VAL A 1 387 ? 24.12955  7.54378   6.95069  1.000 71.55185  ? 282  VAL A HB    1 
ATOM   5175 H  HG11  . VAL A 1 387 ? 25.02697  8.18675   4.80118  1.000 67.11886  ? 282  VAL A HG11  1 
ATOM   5176 H  HG12  . VAL A 1 387 ? 23.91025  9.15368   5.38557  1.000 67.11886  ? 282  VAL A HG12  1 
ATOM   5177 H  HG13  . VAL A 1 387 ? 25.44327  9.55717   5.48833  1.000 67.11886  ? 282  VAL A HG13  1 
ATOM   5178 H  HG21  . VAL A 1 387 ? 26.12146  6.59807   6.18417  1.000 73.40687  ? 282  VAL A HG21  1 
ATOM   5179 H  HG22  . VAL A 1 387 ? 26.93980  7.81711   6.79060  1.000 73.40687  ? 282  VAL A HG22  1 
ATOM   5180 H  HG23  . VAL A 1 387 ? 26.20022  6.79720   7.75823  1.000 73.40687  ? 282  VAL A HG23  1 
ATOM   5181 N  N     . VAL A 1 388 ? 22.80008  10.39118  8.20207  1.000 55.49290  ? 283  VAL A N     1 
ATOM   5182 C  CA    . VAL A 1 388 ? 21.83266  11.34087  7.66648  1.000 58.40222  ? 283  VAL A CA    1 
ATOM   5183 C  C     . VAL A 1 388 ? 22.01512  12.73821  8.24734  1.000 61.25434  ? 283  VAL A C     1 
ATOM   5184 O  O     . VAL A 1 388 ? 21.73479  13.73108  7.56600  1.000 64.05282  ? 283  VAL A O     1 
ATOM   5185 C  CB    . VAL A 1 388 ? 20.40408  10.82525  7.91348  1.000 60.73695  ? 283  VAL A CB    1 
ATOM   5186 C  CG1   . VAL A 1 388 ? 20.25330  9.41257   7.37335  1.000 68.63276  ? 283  VAL A CG1   1 
ATOM   5187 C  CG2   . VAL A 1 388 ? 20.06774  10.88010  9.39710  1.000 61.28936  ? 283  VAL A CG2   1 
ATOM   5188 H  H     . VAL A 1 388 ? 22.51345  9.91129   8.85564  1.000 66.63469  ? 283  VAL A H     1 
ATOM   5189 H  HA    . VAL A 1 388 ? 21.98317  11.40933  6.71068  1.000 70.12588  ? 283  VAL A HA    1 
ATOM   5190 H  HB    . VAL A 1 388 ? 19.77438  11.39493  7.44461  1.000 72.92755  ? 283  VAL A HB    1 
ATOM   5191 H  HG11  . VAL A 1 388 ? 19.32147  9.14968   7.43238  1.000 82.40253  ? 283  VAL A HG11  1 
ATOM   5192 H  HG12  . VAL A 1 388 ? 20.54380  9.39558   6.44803  1.000 82.40253  ? 283  VAL A HG12  1 
ATOM   5193 H  HG13  . VAL A 1 388 ? 20.80064  8.81188   7.90296  1.000 82.40253  ? 283  VAL A HG13  1 
ATOM   5194 H  HG21  . VAL A 1 388 ? 19.25007  10.38245  9.55415  1.000 73.59045  ? 283  VAL A HG21  1 
ATOM   5195 H  HG22  . VAL A 1 388 ? 20.79684  10.48589  9.90099  1.000 73.59045  ? 283  VAL A HG22  1 
ATOM   5196 H  HG23  . VAL A 1 388 ? 19.94697  11.80608  9.65951  1.000 73.59045  ? 283  VAL A HG23  1 
ATOM   5197 N  N     . ASN A 1 389 ? 22.47799  12.85224  9.49238  1.000 60.71877  ? 284  ASN A N     1 
ATOM   5198 C  CA    . ASN A 1 389 ? 22.49326  14.15966  10.14709 1.000 68.16575  ? 284  ASN A CA    1 
ATOM   5199 C  C     . ASN A 1 389 ? 23.28480  15.19950  9.36506  1.000 67.15430  ? 284  ASN A C     1 
ATOM   5200 O  O     . ASN A 1 389 ? 22.76766  16.31289  9.16477  1.000 67.35053  ? 284  ASN A O     1 
ATOM   5201 C  CB    . ASN A 1 389 ? 23.02216  14.01513  11.57882 1.000 65.68191  ? 284  ASN A CB    1 
ATOM   5202 C  CG    . ASN A 1 389 ? 22.09590  13.19628  12.45979 1.000 62.70830  ? 284  ASN A CG    1 
ATOM   5203 O  OD1   . ASN A 1 389 ? 20.98378  12.85463  12.05711 1.000 60.60310  ? 284  ASN A OD1   1 
ATOM   5204 N  ND2   . ASN A 1 389 ? 22.54624  12.88589  13.67148 1.000 60.42020  ? 284  ASN A ND2   1 
ATOM   5205 H  H     . ASN A 1 389 ? 22.78175  12.20421  9.96923  1.000 72.90573  ? 284  ASN A H     1 
ATOM   5206 H  HA    . ASN A 1 389 ? 21.57563  14.47022  10.19609 1.000 81.84212  ? 284  ASN A HA    1 
ATOM   5207 H  HB2   . ASN A 1 389 ? 23.88475  13.57211  11.55508 1.000 78.86150  ? 284  ASN A HB2   1 
ATOM   5208 H  HB3   . ASN A 1 389 ? 23.11255  14.89634  11.97403 1.000 78.86150  ? 284  ASN A HB3   1 
ATOM   5209 H  HD21  . ASN A 1 389 ? 22.05708  12.42329  14.20656 1.000 72.54746  ? 284  ASN A HD21  1 
ATOM   5210 H  HD22  . ASN A 1 389 ? 23.32673  13.14771  13.92024 1.000 72.54746  ? 284  ASN A HD22  1 
ATOM   5211 N  N     . PRO A 1 390 ? 24.50794  14.92769  8.89901  1.000 67.78830  ? 285  PRO A N     1 
ATOM   5212 C  CA    . PRO A 1 390 ? 25.21785  15.94336  8.10059  1.000 67.65761  ? 285  PRO A CA    1 
ATOM   5213 C  C     . PRO A 1 390 ? 24.41094  16.45422  6.91871  1.000 69.00429  ? 285  PRO A C     1 
ATOM   5214 O  O     . PRO A 1 390 ? 24.45573  17.65213  6.61403  1.000 74.41855  ? 285  PRO A O     1 
ATOM   5215 C  CB    . PRO A 1 390 ? 26.48462  15.20519  7.64458  1.000 68.11769  ? 285  PRO A CB    1 
ATOM   5216 C  CG    . PRO A 1 390 ? 26.69847  14.14966  8.66683  1.000 66.11477  ? 285  PRO A CG    1 
ATOM   5217 C  CD    . PRO A 1 390 ? 25.32723  13.72149  9.11766  1.000 64.64976  ? 285  PRO A CD    1 
ATOM   5218 H  HA    . PRO A 1 390 ? 25.46668  16.68933  8.66850  1.000 81.23235  ? 285  PRO A HA    1 
ATOM   5219 H  HB2   . PRO A 1 390 ? 26.34307  14.81612  6.76737  1.000 81.78444  ? 285  PRO A HB2   1 
ATOM   5220 H  HB3   . PRO A 1 390 ? 27.23426  15.82019  7.61769  1.000 81.78444  ? 285  PRO A HB3   1 
ATOM   5221 H  HG2   . PRO A 1 390 ? 27.17728  13.40461  8.27117  1.000 79.38094  ? 285  PRO A HG2   1 
ATOM   5222 H  HG3   . PRO A 1 390 ? 27.20552  14.51295  9.40968  1.000 79.38094  ? 285  PRO A HG3   1 
ATOM   5223 H  HD2   . PRO A 1 390 ? 25.00260  12.98148  8.58110  1.000 77.62293  ? 285  PRO A HD2   1 
ATOM   5224 H  HD3   . PRO A 1 390 ? 25.33366  13.47360  10.05543 1.000 77.62293  ? 285  PRO A HD3   1 
ATOM   5225 N  N     . PHE A 1 391 ? 23.67332  15.57238  6.23965  1.000 69.81349  ? 286  PHE A N     1 
ATOM   5226 C  CA    . PHE A 1 391 ? 22.84379  16.00924  5.12178  1.000 70.37082  ? 286  PHE A CA    1 
ATOM   5227 C  C     . PHE A 1 391 ? 21.74451  16.95415  5.58812  1.000 74.01755  ? 286  PHE A C     1 
ATOM   5228 O  O     . PHE A 1 391 ? 21.46024  17.96115  4.92829  1.000 76.67621  ? 286  PHE A O     1 
ATOM   5229 C  CB    . PHE A 1 391 ? 22.23928  14.79788  4.41083  1.000 73.57968  ? 286  PHE A CB    1 
ATOM   5230 C  CG    . PHE A 1 391 ? 23.19066  14.10649  3.47868  1.000 75.31611  ? 286  PHE A CG    1 
ATOM   5231 C  CD1   . PHE A 1 391 ? 23.35125  14.55585  2.17862  1.000 80.33787  ? 286  PHE A CD1   1 
ATOM   5232 C  CD2   . PHE A 1 391 ? 23.92482  13.00969  3.89917  1.000 75.36008  ? 286  PHE A CD2   1 
ATOM   5233 C  CE1   . PHE A 1 391 ? 24.22509  13.92488  1.31510  1.000 77.02453  ? 286  PHE A CE1   1 
ATOM   5234 C  CE2   . PHE A 1 391 ? 24.80277  12.37480  3.03883  1.000 70.82118  ? 286  PHE A CE2   1 
ATOM   5235 C  CZ    . PHE A 1 391 ? 24.95317  12.83407  1.74598  1.000 75.79929  ? 286  PHE A CZ    1 
ATOM   5236 H  H     . PHE A 1 391 ? 23.63726  14.72916  6.40480  1.000 83.81941  ? 286  PHE A H     1 
ATOM   5237 H  HA    . PHE A 1 391 ? 23.40215  16.48431  4.48661  1.000 84.48820  ? 286  PHE A HA    1 
ATOM   5238 H  HB2   . PHE A 1 391 ? 21.95782  14.15291  5.07844  1.000 88.33884  ? 286  PHE A HB2   1 
ATOM   5239 H  HB3   . PHE A 1 391 ? 21.47530  15.09117  3.89005  1.000 88.33884  ? 286  PHE A HB3   1 
ATOM   5240 H  HD1   . PHE A 1 391 ? 22.86474  15.29144  1.88347  1.000 96.44866  ? 286  PHE A HD1   1 
ATOM   5241 H  HD2   . PHE A 1 391 ? 23.82648  12.69667  4.76936  1.000 90.47531  ? 286  PHE A HD2   1 
ATOM   5242 H  HE1   . PHE A 1 391 ? 24.32297  14.23473  0.44371  1.000 92.47265  ? 286  PHE A HE1   1 
ATOM   5243 H  HE2   . PHE A 1 391 ? 25.29108  11.63933  3.33133  1.000 85.02864  ? 286  PHE A HE2   1 
ATOM   5244 H  HZ    . PHE A 1 391 ? 25.54374  12.40957  1.16639  1.000 91.00237  ? 286  PHE A HZ    1 
ATOM   5245 N  N     . ILE A 1 392 ? 21.11033  16.64466  6.72208  1.000 71.09327  ? 287  ILE A N     1 
ATOM   5246 C  CA    . ILE A 1 392 ? 20.06184  17.51725  7.24315  1.000 75.45242  ? 287  ILE A CA    1 
ATOM   5247 C  C     . ILE A 1 392 ? 20.62526  18.90451  7.52675  1.000 74.59148  ? 287  ILE A C     1 
ATOM   5248 O  O     . ILE A 1 392 ? 19.99593  19.92465  7.21762  1.000 78.94270  ? 287  ILE A O     1 
ATOM   5249 C  CB    . ILE A 1 392 ? 19.42489  16.89883  8.50234  1.000 73.03948  ? 287  ILE A CB    1 
ATOM   5250 C  CG1   . ILE A 1 392 ? 18.94238  15.46937  8.22874  1.000 71.17066  ? 287  ILE A CG1   1 
ATOM   5251 C  CG2   . ILE A 1 392 ? 18.26623  17.75850  8.99394  1.000 74.37758  ? 287  ILE A CG2   1 
ATOM   5252 C  CD1   . ILE A 1 392 ? 17.91871  15.35083  7.11817  1.000 72.80492  ? 287  ILE A CD1   1 
ATOM   5253 H  H     . ILE A 1 392 ? 21.26682  15.94668  7.19950  1.000 85.35513  ? 287  ILE A H     1 
ATOM   5254 H  HA    . ILE A 1 392 ? 19.36870  17.60324  6.57004  1.000 90.58612  ? 287  ILE A HA    1 
ATOM   5255 H  HB    . ILE A 1 392 ? 20.10652  16.86508  9.19165  1.000 87.69060  ? 287  ILE A HB    1 
ATOM   5256 H  HG12  . ILE A 1 392 ? 19.70764  14.92765  7.98009  1.000 85.44801  ? 287  ILE A HG12  1 
ATOM   5257 H  HG13  . ILE A 1 392 ? 18.53757  15.12009  9.03808  1.000 85.44801  ? 287  ILE A HG13  1 
ATOM   5258 H  HG21  . ILE A 1 392 ? 17.83171  17.30874  9.73543  1.000 89.29631  ? 287  ILE A HG21  1 
ATOM   5259 H  HG22  . ILE A 1 392 ? 18.61121  18.61732  9.28430  1.000 89.29631  ? 287  ILE A HG22  1 
ATOM   5260 H  HG23  . ILE A 1 392 ? 17.63560  17.88377  8.26764  1.000 89.29631  ? 287  ILE A HG23  1 
ATOM   5261 H  HD11  . ILE A 1 392 ? 17.67447  14.41810  7.01204  1.000 87.40912  ? 287  ILE A HD11  1 
ATOM   5262 H  HD12  . ILE A 1 392 ? 17.13583  15.87307  7.35325  1.000 87.40912  ? 287  ILE A HD12  1 
ATOM   5263 H  HD13  . ILE A 1 392 ? 18.30568  15.68719  6.29476  1.000 87.40912  ? 287  ILE A HD13  1 
ATOM   5264 N  N     . TYR A 1 393 ? 21.82108  18.96455  8.11696  1.000 71.32804  ? 288  TYR A N     1 
ATOM   5265 C  CA    . TYR A 1 393 ? 22.45360  20.25191  8.38250  1.000 73.42783  ? 288  TYR A CA    1 
ATOM   5266 C  C     . TYR A 1 393 ? 22.67757  21.02633  7.08924  1.000 72.63083  ? 288  TYR A C     1 
ATOM   5267 O  O     . TYR A 1 393 ? 22.37672  22.22277  7.00629  1.000 73.85082  ? 288  TYR A O     1 
ATOM   5268 C  CB    . TYR A 1 393 ? 23.77785  20.03833  9.11745  1.000 71.47703  ? 288  TYR A CB    1 
ATOM   5269 C  CG    . TYR A 1 393 ? 23.63670  19.30679  10.43295 1.000 69.89579  ? 288  TYR A CG    1 
ATOM   5270 C  CD1   . TYR A 1 393 ? 22.60673  19.61199  11.31345 1.000 70.40132  ? 288  TYR A CD1   1 
ATOM   5271 C  CD2   . TYR A 1 393 ? 24.52845  18.30335  10.79098 1.000 67.95965  ? 288  TYR A CD2   1 
ATOM   5272 C  CE1   . TYR A 1 393 ? 22.47460  18.94528  12.51513 1.000 70.02433  ? 288  TYR A CE1   1 
ATOM   5273 C  CE2   . TYR A 1 393 ? 24.40109  17.62859  11.98959 1.000 70.07988  ? 288  TYR A CE2   1 
ATOM   5274 C  CZ    . TYR A 1 393 ? 23.37277  17.95197  12.84673 1.000 70.09062  ? 288  TYR A CZ    1 
ATOM   5275 O  OH    . TYR A 1 393 ? 23.24637  17.27900  14.04049 1.000 61.87114  ? 288  TYR A OH    1 
ATOM   5276 H  H     . TYR A 1 393 ? 22.27965  18.28225  8.36950  1.000 85.63686  ? 288  TYR A H     1 
ATOM   5277 H  HA    . TYR A 1 393 ? 21.87123  20.77752  8.95302  1.000 88.15661  ? 288  TYR A HA    1 
ATOM   5278 H  HB2   . TYR A 1 393 ? 24.36772  19.51670  8.55101  1.000 85.81566  ? 288  TYR A HB2   1 
ATOM   5279 H  HB3   . TYR A 1 393 ? 24.17481  20.90398  9.30177  1.000 85.81566  ? 288  TYR A HB3   1 
ATOM   5280 H  HD1   . TYR A 1 393 ? 21.99587  20.27660  11.08975 1.000 84.52479  ? 288  TYR A HD1   1 
ATOM   5281 H  HD2   . TYR A 1 393 ? 25.22317  18.08211  10.21365 1.000 81.59479  ? 288  TYR A HD2   1 
ATOM   5282 H  HE1   . TYR A 1 393 ? 21.78384  19.16457  13.09795 1.000 84.07241  ? 288  TYR A HE1   1 
ATOM   5283 H  HE2   . TYR A 1 393 ? 25.00623  16.95983  12.21642 1.000 84.13908  ? 288  TYR A HE2   1 
ATOM   5284 H  HH    . TYR A 1 393 ? 22.55436  17.53435  14.44238 1.000 74.28858  ? 288  TYR A HH    1 
ATOM   5285 N  N     . ALA A 1 394 ? 23.20161  20.35285  6.06218  1.000 74.50277  ? 289  ALA A N     1 
ATOM   5286 C  CA    . ALA A 1 394 ? 23.52374  21.03640  4.81508  1.000 76.05952  ? 289  ALA A CA    1 
ATOM   5287 C  C     . ALA A 1 394 ? 22.27462  21.52428  4.09199  1.000 76.75379  ? 289  ALA A C     1 
ATOM   5288 O  O     . ALA A 1 394 ? 22.30735  22.57781  3.44719  1.000 78.09868  ? 289  ALA A O     1 
ATOM   5289 C  CB    . ALA A 1 394 ? 24.33028  20.10893  3.90569  1.000 82.80068  ? 289  ALA A CB    1 
ATOM   5290 H  H     . ALA A 1 394 ? 23.37712  19.51095  6.06398  1.000 89.44654  ? 289  ALA A H     1 
ATOM   5291 H  HA    . ALA A 1 394 ? 24.06859  21.81207  5.02095  1.000 91.31464  ? 289  ALA A HA    1 
ATOM   5292 H  HB1   . ALA A 1 394 ? 24.53177  20.57431  3.07881  1.000 99.40403  ? 289  ALA A HB1   1 
ATOM   5293 H  HB2   . ALA A 1 394 ? 25.15352  19.86286  4.35583  1.000 99.40403  ? 289  ALA A HB2   1 
ATOM   5294 H  HB3   . ALA A 1 394 ? 23.80531  19.31494  3.71893  1.000 99.40403  ? 289  ALA A HB3   1 
ATOM   5295 N  N     . TYR A 1 395 ? 21.17052  20.78554  4.18361  1.000 79.38940  ? 290  TYR A N     1 
ATOM   5296 C  CA    . TYR A 1 395 ? 19.96356  21.14422  3.45190  1.000 80.60933  ? 290  TYR A CA    1 
ATOM   5297 C  C     . TYR A 1 395 ? 19.07896  22.14337  4.18718  1.000 81.36182  ? 290  TYR A C     1 
ATOM   5298 O  O     . TYR A 1 395 ? 18.27557  22.82322  3.53744  1.000 84.78690  ? 290  TYR A O     1 
ATOM   5299 C  CB    . TYR A 1 395 ? 19.14149  19.88740  3.13425  1.000 85.25349  ? 290  TYR A CB    1 
ATOM   5300 C  CG    . TYR A 1 395 ? 19.58298  19.16023  1.87909  1.000 89.82618  ? 290  TYR A CG    1 
ATOM   5301 C  CD1   . TYR A 1 395 ? 19.12170  19.55211  0.62832  1.000 95.37329  ? 290  TYR A CD1   1 
ATOM   5302 C  CD2   . TYR A 1 395 ? 20.45627  18.08169  1.94466  1.000 90.19099  ? 290  TYR A CD2   1 
ATOM   5303 C  CE1   . TYR A 1 395 ? 19.52001  18.89379  -0.52188 1.000 99.32763  ? 290  TYR A CE1   1 
ATOM   5304 C  CE2   . TYR A 1 395 ? 20.85932  17.41534  0.79866  1.000 95.14821  ? 290  TYR A CE2   1 
ATOM   5305 C  CZ    . TYR A 1 395 ? 20.38781  17.82660  -0.43146 1.000 102.27079 ? 290  TYR A CZ    1 
ATOM   5306 O  OH    . TYR A 1 395 ? 20.78460  17.17039  -1.57516 1.000 106.80009 ? 290  TYR A OH    1 
ATOM   5307 H  H     . TYR A 1 395 ? 21.09758  20.07458  4.66196  1.000 95.31049  ? 290  TYR A H     1 
ATOM   5308 H  HA    . TYR A 1 395 ? 20.22968  21.55147  2.61271  1.000 96.77441  ? 290  TYR A HA    1 
ATOM   5309 H  HB2   . TYR A 1 395 ? 19.22096  19.26839  3.87682  1.000 102.34740 ? 290  TYR A HB2   1 
ATOM   5310 H  HB3   . TYR A 1 395 ? 18.21396  20.14492  3.01481  1.000 102.34740 ? 290  TYR A HB3   1 
ATOM   5311 H  HD1   . TYR A 1 395 ? 18.53435  20.27020  0.56296  1.000 114.49117 ? 290  TYR A HD1   1 
ATOM   5312 H  HD2   . TYR A 1 395 ? 20.77585  17.80214  2.77208  1.000 108.27240 ? 290  TYR A HD2   1 
ATOM   5313 H  HE1   . TYR A 1 395 ? 19.20380  19.16999  -1.35172 1.000 119.23637 ? 290  TYR A HE1   1 
ATOM   5314 H  HE2   . TYR A 1 395 ? 21.44440  16.69488  0.85807  1.000 114.22107 ? 290  TYR A HE2   1 
ATOM   5315 H  HH    . TYR A 1 395 ? 21.32860  16.56013  -1.38218 1.000 128.20333 ? 290  TYR A HH    1 
ATOM   5316 N  N     . ARG A 1 396 ? 19.20474  22.26267  5.51353  1.000 80.75178  ? 291  ARG A N     1 
ATOM   5317 C  CA    . ARG A 1 396 ? 18.30994  23.11277  6.28699  1.000 83.02913  ? 291  ARG A CA    1 
ATOM   5318 C  C     . ARG A 1 396 ? 18.98463  24.26552  7.01832  1.000 76.77873  ? 291  ARG A C     1 
ATOM   5319 O  O     . ARG A 1 396 ? 18.28125  25.19415  7.43016  1.000 81.98662  ? 291  ARG A O     1 
ATOM   5320 C  CB    . ARG A 1 396 ? 17.53507  22.28067  7.32507  1.000 82.24814  ? 291  ARG A CB    1 
ATOM   5321 C  CG    . ARG A 1 396 ? 16.30720  21.57795  6.76737  1.000 80.88449  ? 291  ARG A CG    1 
ATOM   5322 C  CD    . ARG A 1 396 ? 15.31514  21.21593  7.86426  1.000 81.00255  ? 291  ARG A CD    1 
ATOM   5323 N  NE    . ARG A 1 396 ? 14.60839  22.38298  8.38279  1.000 83.98353  ? 291  ARG A NE    1 
ATOM   5324 C  CZ    . ARG A 1 396 ? 13.47311  22.86127  7.88735  1.000 84.71937  ? 291  ARG A CZ    1 
ATOM   5325 N  NH1   . ARG A 1 396 ? 12.88509  22.30577  6.83953  1.000 89.50810  ? 291  ARG A NH1   1 
ATOM   5326 N  NH2   . ARG A 1 396 ? 12.91321  23.92442  8.45847  1.000 83.83955  ? 291  ARG A NH2   1 
ATOM   5327 H  H     . ARG A 1 396 ? 19.80197  21.85926  5.98278  1.000 96.94535  ? 291  ARG A H     1 
ATOM   5328 H  HA    . ARG A 1 396 ? 17.67292  23.50056  5.66673  1.000 99.67817  ? 291  ARG A HA    1 
ATOM   5329 H  HB2   . ARG A 1 396 ? 18.12718  21.60026  7.68193  1.000 98.74099  ? 291  ARG A HB2   1 
ATOM   5330 H  HB3   . ARG A 1 396 ? 17.23947  22.86968  8.03683  1.000 98.74099  ? 291  ARG A HB3   1 
ATOM   5331 H  HG2   . ARG A 1 396 ? 15.86145  22.16477  6.13661  1.000 97.10460  ? 291  ARG A HG2   1 
ATOM   5332 H  HG3   . ARG A 1 396 ? 16.58059  20.76000  6.32339  1.000 97.10460  ? 291  ARG A HG3   1 
ATOM   5333 H  HD2   . ARG A 1 396 ? 14.65703  20.59964  7.50651  1.000 97.24628  ? 291  ARG A HD2   1 
ATOM   5334 H  HD3   . ARG A 1 396 ? 15.79240  20.80138  8.59996  1.000 97.24628  ? 291  ARG A HD3   1 
ATOM   5335 H  HE    . ARG A 1 396 ? 14.95203  22.79018  9.05784  1.000 100.82345 ? 291  ARG A HE    1 
ATOM   5336 H  HH11  . ARG A 1 396 ? 13.23820  21.61806  6.46274  1.000 107.45293 ? 291  ARG A HH11  1 
ATOM   5337 H  HH12  . ARG A 1 396 ? 12.14997  22.63258  6.53558  1.000 107.45293 ? 291  ARG A HH12  1 
ATOM   5338 H  HH21  . ARG A 1 396 ? 13.28657  24.29310  9.13986  1.000 100.65068 ? 291  ARG A HH21  1 
ATOM   5339 H  HH22  . ARG A 1 396 ? 12.17793  24.24300  8.14627  1.000 100.65068 ? 291  ARG A HH22  1 
ATOM   5340 N  N     . ILE A 1 397 ? 20.30267  24.24425  7.19588  1.000 77.24256  ? 292  ILE A N     1 
ATOM   5341 C  CA    . ILE A 1 397 ? 21.01090  25.28051  7.94348  1.000 77.79234  ? 292  ILE A CA    1 
ATOM   5342 C  C     . ILE A 1 397 ? 22.02011  25.92694  7.00494  1.000 76.90881  ? 292  ILE A C     1 
ATOM   5343 O  O     . ILE A 1 397 ? 22.99364  25.28618  6.58737  1.000 76.24939  ? 292  ILE A O     1 
ATOM   5344 C  CB    . ILE A 1 397 ? 21.69043  24.72034  9.20170  1.000 79.38502  ? 292  ILE A CB    1 
ATOM   5345 C  CG1   . ILE A 1 397 ? 20.66031  23.93446  10.02264 1.000 80.42685  ? 292  ILE A CG1   1 
ATOM   5346 C  CG2   . ILE A 1 397 ? 22.31147  25.84841  10.01654 1.000 77.65428  ? 292  ILE A CG2   1 
ATOM   5347 C  CD1   . ILE A 1 397 ? 21.04992  23.66847  11.46364 1.000 77.12930  ? 292  ILE A CD1   1 
ATOM   5348 H  H     . ILE A 1 397 ? 20.81753  23.62849  6.88709  1.000 92.73429  ? 292  ILE A H     1 
ATOM   5349 H  HA    . ILE A 1 397 ? 20.37988  25.96468  8.21669  1.000 93.39403  ? 292  ILE A HA    1 
ATOM   5350 H  HB    . ILE A 1 397 ? 22.40633  24.11849  8.94447  1.000 95.30524  ? 292  ILE A HB    1 
ATOM   5351 H  HG12  . ILE A 1 397 ? 19.83067  24.43691  10.03475 1.000 96.55544  ? 292  ILE A HG12  1 
ATOM   5352 H  HG13  . ILE A 1 397 ? 20.52102  23.07426  9.59656  1.000 96.55544  ? 292  ILE A HG13  1 
ATOM   5353 H  HG21  . ILE A 1 397 ? 22.77918  25.46846  10.77667 1.000 93.22835  ? 292  ILE A HG21  1 
ATOM   5354 H  HG22  . ILE A 1 397 ? 22.93393  26.33734  9.45583  1.000 93.22835  ? 292  ILE A HG22  1 
ATOM   5355 H  HG23  . ILE A 1 397 ? 21.60742  26.44074  10.32370 1.000 93.22835  ? 292  ILE A HG23  1 
ATOM   5356 H  HD11  . ILE A 1 397 ? 20.38445  23.09095  11.86926 1.000 92.59837  ? 292  ILE A HD11  1 
ATOM   5357 H  HD12  . ILE A 1 397 ? 21.91807  23.23616  11.48141 1.000 92.59837  ? 292  ILE A HD12  1 
ATOM   5358 H  HD13  . ILE A 1 397 ? 21.09067  24.51210  11.94064 1.000 92.59837  ? 292  ILE A HD13  1 
ATOM   5359 N  N     . ARG A 1 398 ? 21.79467  27.20502  6.68576  1.000 81.51374  ? 293  ARG A N     1 
ATOM   5360 C  CA    . ARG A 1 398 ? 22.61357  27.88088  5.68426  1.000 81.00296  ? 293  ARG A CA    1 
ATOM   5361 C  C     . ARG A 1 398 ? 24.06368  27.99990  6.13455  1.000 77.90535  ? 293  ARG A C     1 
ATOM   5362 O  O     . ARG A 1 398 ? 24.98632  27.84327  5.32640  1.000 80.06626  ? 293  ARG A O     1 
ATOM   5363 C  CB    . ARG A 1 398 ? 22.03342  29.26411  5.38562  1.000 88.27797  ? 293  ARG A CB    1 
ATOM   5364 H  H     . ARG A 1 398 ? 21.17962  27.69632  7.03208  1.000 97.85970  ? 293  ARG A H     1 
ATOM   5365 H  HA    . ARG A 1 398 ? 22.59752  27.35859  4.86704  1.000 97.24676  ? 293  ARG A HA    1 
ATOM   5366 N  N     . GLU A 1 399 ? 24.28749  28.28296  7.41892  1.000 79.26378  ? 294  GLU A N     1 
ATOM   5367 C  CA    . GLU A 1 399 ? 25.65435  28.43512  7.90733  1.000 81.51179  ? 294  GLU A CA    1 
ATOM   5368 C  C     . GLU A 1 399 ? 26.43396  27.13204  7.77196  1.000 77.75732  ? 294  GLU A C     1 
ATOM   5369 O  O     . GLU A 1 399 ? 27.60462  27.13875  7.37255  1.000 74.98764  ? 294  GLU A O     1 
ATOM   5370 C  CB    . GLU A 1 399 ? 25.64027  28.90726  9.36094  1.000 77.86346  ? 294  GLU A CB    1 
ATOM   5371 C  CG    . GLU A 1 399 ? 26.93418  29.57441  9.80556  1.000 83.28337  ? 294  GLU A CG    1 
ATOM   5372 C  CD    . GLU A 1 399 ? 27.22614  30.85624  9.04219  1.000 87.77348  ? 294  GLU A CD    1 
ATOM   5373 O  OE1   . GLU A 1 399 ? 26.26882  31.48008  8.53617  1.000 87.06398  ? 294  GLU A OE1   1 
ATOM   5374 O  OE2   . GLU A 1 399 ? 28.41296  31.23538  8.94036  1.000 82.66555  ? 294  GLU A OE2   1 
ATOM   5375 H  H     . GLU A 1 399 ? 23.67706  28.38957  8.01525  1.000 95.15975  ? 294  GLU A H     1 
ATOM   5376 H  HA    . GLU A 1 399 ? 26.10521  29.11097  7.37738  1.000 97.85737  ? 294  GLU A HA    1 
ATOM   5377 H  HB2   . GLU A 1 399 ? 24.92277  29.55045  9.47228  1.000 93.47937  ? 294  GLU A HB2   1 
ATOM   5378 H  HB3   . GLU A 1 399 ? 25.49054  28.14041  9.93577  1.000 93.47937  ? 294  GLU A HB3   1 
ATOM   5379 H  HG2   . GLU A 1 399 ? 26.86886  29.79460  10.74797 1.000 99.98326  ? 294  GLU A HG2   1 
ATOM   5380 H  HG3   . GLU A 1 399 ? 27.67233  28.96259  9.65819  1.000 99.98326  ? 294  GLU A HG3   1 
ATOM   5381 N  N     . PHE A 1 400 ? 25.80338  26.00235  8.10740  1.000 79.19104  ? 295  PHE A N     1 
ATOM   5382 C  CA    . PHE A 1 400 ? 26.44549  24.70756  7.90196  1.000 77.72641  ? 295  PHE A CA    1 
ATOM   5383 C  C     . PHE A 1 400 ? 26.68764  24.44332  6.42067  1.000 76.43371  ? 295  PHE A C     1 
ATOM   5384 O  O     . PHE A 1 400 ? 27.75582  23.95471  6.03365  1.000 73.22213  ? 295  PHE A O     1 
ATOM   5385 C  CB    . PHE A 1 400 ? 25.58708  23.59137  8.50052  1.000 78.23719  ? 295  PHE A CB    1 
ATOM   5386 C  CG    . PHE A 1 400 ? 25.97197  23.20906  9.90105  1.000 76.05223  ? 295  PHE A CG    1 
ATOM   5387 C  CD1   . PHE A 1 400 ? 27.15596  22.53252  10.14575 1.000 72.00229  ? 295  PHE A CD1   1 
ATOM   5388 C  CD2   . PHE A 1 400 ? 25.14399  23.50928  10.97019 1.000 73.01648  ? 295  PHE A CD2   1 
ATOM   5389 C  CE1   . PHE A 1 400 ? 27.51379  22.17327  11.43035 1.000 65.48542  ? 295  PHE A CE1   1 
ATOM   5390 C  CE2   . PHE A 1 400 ? 25.49584  23.15121  12.25814 1.000 73.75533  ? 295  PHE A CE2   1 
ATOM   5391 C  CZ    . PHE A 1 400 ? 26.68283  22.48128  12.48812 1.000 70.71646  ? 295  PHE A CZ    1 
ATOM   5392 H  H     . PHE A 1 400 ? 25.01571  25.96104  8.45013  1.000 95.07246  ? 295  PHE A H     1 
ATOM   5393 H  HA    . PHE A 1 400 ? 27.30153  24.71098  8.35812  1.000 93.31491  ? 295  PHE A HA    1 
ATOM   5394 H  HB2   . PHE A 1 400 ? 24.66291  23.88545  8.51839  1.000 93.92784  ? 295  PHE A HB2   1 
ATOM   5395 H  HB3   . PHE A 1 400 ? 25.67305  22.80101  7.94478  1.000 93.92784  ? 295  PHE A HB3   1 
ATOM   5396 H  HD1   . PHE A 1 400 ? 27.71697  22.31754  9.43585  1.000 86.44597  ? 295  PHE A HD1   1 
ATOM   5397 H  HD2   . PHE A 1 400 ? 24.34263  23.95663  10.81985 1.000 87.66300  ? 295  PHE A HD2   1 
ATOM   5398 H  HE1   . PHE A 1 400 ? 28.31391  21.72427  11.58237 1.000 78.62572  ? 295  PHE A HE1   1 
ATOM   5399 H  HE2   . PHE A 1 400 ? 24.93442  23.36087  12.96931 1.000 88.54961  ? 295  PHE A HE2   1 
ATOM   5400 H  HZ    . PHE A 1 400 ? 26.92089  22.23866  13.35377 1.000 84.90296  ? 295  PHE A HZ    1 
ATOM   5401 N  N     . ARG A 1 401 ? 25.69880  24.75047  5.57859  1.000 77.45038  ? 296  ARG A N     1 
ATOM   5402 C  CA    . ARG A 1 401 ? 25.83925  24.52921  4.14230  1.000 80.94022  ? 296  ARG A CA    1 
ATOM   5403 C  C     . ARG A 1 401 ? 27.01076  25.32186  3.57823  1.000 81.11771  ? 296  ARG A C     1 
ATOM   5404 O  O     . ARG A 1 401 ? 27.84937  24.78022  2.84839  1.000 80.61416  ? 296  ARG A O     1 
ATOM   5405 C  CB    . ARG A 1 401 ? 24.52854  24.90171  3.44219  1.000 82.75763  ? 296  ARG A CB    1 
ATOM   5406 C  CG    . ARG A 1 401 ? 24.66105  25.54359  2.06587  1.000 87.28667  ? 296  ARG A CG    1 
ATOM   5407 C  CD    . ARG A 1 401 ? 23.28773  25.96811  1.54247  1.000 90.89032  ? 296  ARG A CD    1 
ATOM   5408 N  NE    . ARG A 1 401 ? 22.52577  24.84453  1.00665  1.000 98.53724  ? 296  ARG A NE    1 
ATOM   5409 C  CZ    . ARG A 1 401 ? 21.92315  24.82976  -0.17718 1.000 105.69773 ? 296  ARG A CZ    1 
ATOM   5410 N  NH1   . ARG A 1 401 ? 21.92160  25.88971  -0.97050 1.000 107.67244 ? 296  ARG A NH1   1 
ATOM   5411 N  NH2   . ARG A 1 401 ? 21.29587  23.72511  -0.57065 1.000 100.68069 ? 296  ARG A NH2   1 
ATOM   5412 H  H     . ARG A 1 401 ? 24.94230  25.08575  5.81286  1.000 92.98367  ? 296  ARG A H     1 
ATOM   5413 H  HA    . ARG A 1 401 ? 26.01586  23.59022  3.97497  1.000 97.17148  ? 296  ARG A HA    1 
ATOM   5414 H  HB2   . ARG A 1 401 ? 24.00443  24.09306  3.33125  1.000 99.35237  ? 296  ARG A HB2   1 
ATOM   5415 H  HB3   . ARG A 1 401 ? 24.05240  25.53086  4.00642  1.000 99.35237  ? 296  ARG A HB3   1 
ATOM   5416 H  HG2   . ARG A 1 401 ? 25.22604  26.32974  2.12619  1.000 104.78722 ? 296  ARG A HG2   1 
ATOM   5417 H  HG3   . ARG A 1 401 ? 25.04556  24.90556  1.44461  1.000 104.78722 ? 296  ARG A HG3   1 
ATOM   5418 H  HD2   . ARG A 1 401 ? 22.77768  26.35896  2.26910  1.000 109.11160 ? 296  ARG A HD2   1 
ATOM   5419 H  HD3   . ARG A 1 401 ? 23.40542  26.61839  0.83242  1.000 109.11160 ? 296  ARG A HD3   1 
ATOM   5420 H  HE    . ARG A 1 401 ? 22.46210  24.13882  1.49402  1.000 118.28791 ? 296  ARG A HE    1 
ATOM   5421 H  HH11  . ARG A 1 401 ? 22.31769  26.61208  -0.72373 1.000 129.25015 ? 296  ARG A HH11  1 
ATOM   5422 H  HH12  . ARG A 1 401 ? 21.52451  25.85585  -1.73258 1.000 129.25015 ? 296  ARG A HH12  1 
ATOM   5423 H  HH21  . ARG A 1 401 ? 21.28403  23.03259  -0.06087 1.000 120.86005 ? 296  ARG A HH21  1 
ATOM   5424 H  HH22  . ARG A 1 401 ? 20.90207  23.70327  -1.33487 1.000 120.86005 ? 296  ARG A HH22  1 
ATOM   5425 N  N     . GLN A 1 402 ? 27.08578  26.61222  3.90871  1.000 76.61730  ? 297  GLN A N     1 
ATOM   5426 C  CA    . GLN A 1 402 ? 28.14708  27.45058  3.36223  1.000 80.25265  ? 297  GLN A CA    1 
ATOM   5427 C  C     . GLN A 1 402 ? 29.50801  27.04714  3.91595  1.000 75.76014  ? 297  GLN A C     1 
ATOM   5428 O  O     . GLN A 1 402 ? 30.51314  27.08672  3.19696  1.000 73.86703  ? 297  GLN A O     1 
ATOM   5429 C  CB    . GLN A 1 402 ? 27.85531  28.92082  3.66178  1.000 83.22859  ? 297  GLN A CB    1 
ATOM   5430 C  CG    . GLN A 1 402 ? 28.46320  29.89274  2.65924  1.000 95.43182  ? 297  GLN A CG    1 
ATOM   5431 C  CD    . GLN A 1 402 ? 29.57071  30.74527  3.25432  1.000 98.93148  ? 297  GLN A CD    1 
ATOM   5432 O  OE1   . GLN A 1 402 ? 29.57397  31.03872  4.45110  1.000 97.16103  ? 297  GLN A OE1   1 
ATOM   5433 N  NE2   . GLN A 1 402 ? 30.52000  31.14799  2.41606  1.000 95.86890  ? 297  GLN A NE2   1 
ATOM   5434 H  H     . GLN A 1 402 ? 26.54334  27.01833  4.43827  1.000 91.98398  ? 297  GLN A H     1 
ATOM   5435 H  HA    . GLN A 1 402 ? 28.17208  27.33994  2.39889  1.000 96.34640  ? 297  GLN A HA    1 
ATOM   5436 H  HB2   . GLN A 1 402 ? 26.89452  29.05405  3.65587  1.000 99.91752  ? 297  GLN A HB2   1 
ATOM   5437 H  HB3   . GLN A 1 402 ? 28.21479  29.13664  4.53648  1.000 99.91752  ? 297  GLN A HB3   1 
ATOM   5438 H  HG2   . GLN A 1 402 ? 28.83834  29.38913  1.91995  1.000 114.56139 ? 297  GLN A HG2   1 
ATOM   5439 H  HG3   . GLN A 1 402 ? 27.76860  30.48799  2.33660  1.000 114.56139 ? 297  GLN A HG3   1 
ATOM   5440 H  HE21  . GLN A 1 402 ? 30.48468  30.92363  1.58659  1.000 115.08589 ? 297  GLN A HE21  1 
ATOM   5441 H  HE22  . GLN A 1 402 ? 31.16964  31.63297  2.70305  1.000 115.08589 ? 297  GLN A HE22  1 
ATOM   5442 N  N     . THR A 1 403 ? 29.56287  26.65620  5.19066  1.000 74.56073  ? 298  THR A N     1 
ATOM   5443 C  CA    . THR A 1 403 ? 30.82314  26.18908  5.75831  1.000 74.47492  ? 298  THR A CA    1 
ATOM   5444 C  C     . THR A 1 403 ? 31.27443  24.89165  5.09763  1.000 75.64444  ? 298  THR A C     1 
ATOM   5445 O  O     . THR A 1 403 ? 32.46147  24.72399  4.79556  1.000 74.82953  ? 298  THR A O     1 
ATOM   5446 C  CB    . THR A 1 403 ? 30.68296  26.00195  7.26829  1.000 71.23267  ? 298  THR A CB    1 
ATOM   5447 O  OG1   . THR A 1 403 ? 30.19435  27.21407  7.85658  1.000 72.00489  ? 298  THR A OG1   1 
ATOM   5448 C  CG2   . THR A 1 403 ? 32.02822  25.64140  7.89206  1.000 73.23268  ? 298  THR A CG2   1 
ATOM   5449 H  H     . THR A 1 403 ? 28.89767  26.65234  5.73571  1.000 89.51609  ? 298  THR A H     1 
ATOM   5450 H  HA    . THR A 1 403 ? 31.50493  26.86131  5.60289  1.000 89.41312  ? 298  THR A HA    1 
ATOM   5451 H  HB    . THR A 1 403 ? 30.06091  25.28003  7.44935  1.000 85.52242  ? 298  THR A HB    1 
ATOM   5452 H  HG1   . THR A 1 403 ? 29.43705  27.40005  7.54432  1.000 86.44908  ? 298  THR A HG1   1 
ATOM   5453 H  HG21  . THR A 1 403 ? 31.95518  25.63806  8.85930  1.000 87.92244  ? 298  THR A HG21  1 
ATOM   5454 H  HG22  . THR A 1 403 ? 32.30671  24.76122  7.59436  1.000 87.92244  ? 298  THR A HG22  1 
ATOM   5455 H  HG23  . THR A 1 403 ? 32.70016  26.28977  7.62935  1.000 87.92244  ? 298  THR A HG23  1 
ATOM   5456 N  N     . PHE A 1 404 ? 30.34477  23.96009  4.86928  1.000 76.05266  ? 299  PHE A N     1 
ATOM   5457 C  CA    . PHE A 1 404 ? 30.68658  22.74158  4.14277  1.000 79.57544  ? 299  PHE A CA    1 
ATOM   5458 C  C     . PHE A 1 404 ? 31.28551  23.07959  2.78283  1.000 81.91003  ? 299  PHE A C     1 
ATOM   5459 O  O     . PHE A 1 404 ? 32.30567  22.51099  2.37739  1.000 85.04141  ? 299  PHE A O     1 
ATOM   5460 C  CB    . PHE A 1 404 ? 29.44947  21.85545  3.96938  1.000 79.22475  ? 299  PHE A CB    1 
ATOM   5461 C  CG    . PHE A 1 404 ? 28.92215  21.26421  5.25329  1.000 73.24924  ? 299  PHE A CG    1 
ATOM   5462 C  CD1   . PHE A 1 404 ? 29.52448  21.53488  6.47244  1.000 78.82326  ? 299  PHE A CD1   1 
ATOM   5463 C  CD2   . PHE A 1 404 ? 27.81916  20.42489  5.23134  1.000 68.26811  ? 299  PHE A CD2   1 
ATOM   5464 C  CE1   . PHE A 1 404 ? 29.03102  20.98525  7.64248  1.000 79.05095  ? 299  PHE A CE1   1 
ATOM   5465 C  CE2   . PHE A 1 404 ? 27.32325  19.87215  6.39667  1.000 67.52509  ? 299  PHE A CE2   1 
ATOM   5466 C  CZ    . PHE A 1 404 ? 27.92899  20.15241  7.60312  1.000 74.32039  ? 299  PHE A CZ    1 
ATOM   5467 H  H     . PHE A 1 404 ? 29.52394  24.01049  5.12087  1.000 91.30640  ? 299  PHE A H     1 
ATOM   5468 H  HA    . PHE A 1 404 ? 31.33956  22.24477  4.66015  1.000 95.53374  ? 299  PHE A HA    1 
ATOM   5469 H  HB2   . PHE A 1 404 ? 28.73946  22.38828  3.57837  1.000 95.11291  ? 299  PHE A HB2   1 
ATOM   5470 H  HB3   . PHE A 1 404 ? 29.67592  21.11994  3.37892  1.000 95.11291  ? 299  PHE A HB3   1 
ATOM   5471 H  HD1   . PHE A 1 404 ? 30.26843  22.09205  6.50413  1.000 94.63113  ? 299  PHE A HD1   1 
ATOM   5472 H  HD2   . PHE A 1 404 ? 27.40694  20.23097  4.42055  1.000 81.96495  ? 299  PHE A HD2   1 
ATOM   5473 H  HE1   . PHE A 1 404 ? 29.44089  21.17628  8.45513  1.000 94.90435  ? 299  PHE A HE1   1 
ATOM   5474 H  HE2   . PHE A 1 404 ? 26.58168  19.31169  6.36722  1.000 81.07332  ? 299  PHE A HE2   1 
ATOM   5475 H  HZ    . PHE A 1 404 ? 27.59665  19.78178  8.38867  1.000 89.22768  ? 299  PHE A HZ    1 
ATOM   5476 N  N     . ARG A 1 405 ? 30.65851  24.01368  2.06479  1.000 81.47211  ? 300  ARG A N     1 
ATOM   5477 C  CA    . ARG A 1 405 ? 31.14884  24.39605  0.74527  1.000 84.66227  ? 300  ARG A CA    1 
ATOM   5478 C  C     . ARG A 1 405 ? 32.57372  24.93038  0.82642  1.000 86.46726  ? 300  ARG A C     1 
ATOM   5479 O  O     . ARG A 1 405 ? 33.44436  24.53480  0.04254  1.000 92.39260  ? 300  ARG A O     1 
ATOM   5480 C  CB    . ARG A 1 405 ? 30.21551  25.44050  0.13177  1.000 85.19528  ? 300  ARG A CB    1 
ATOM   5481 C  CG    . ARG A 1 405 ? 30.20068  25.45511  -1.38753 1.000 88.85327  ? 300  ARG A CG    1 
ATOM   5482 C  CD    . ARG A 1 405 ? 28.93083  24.81680  -1.93731 1.000 93.75701  ? 300  ARG A CD    1 
ATOM   5483 N  NE    . ARG A 1 405 ? 27.72979  25.47740  -1.43810 1.000 95.62538  ? 300  ARG A NE    1 
ATOM   5484 C  CZ    . ARG A 1 405 ? 26.49603  25.19842  -1.83618 1.000 101.58145 ? 300  ARG A CZ    1 
ATOM   5485 N  NH1   . ARG A 1 405 ? 26.25779  24.28230  -2.76101 1.000 105.85231 ? 300  ARG A NH1   1 
ATOM   5486 N  NH2   . ARG A 1 405 ? 25.47539  25.85695  -1.29395 1.000 98.73574  ? 300  ARG A NH2   1 
ATOM   5487 H  H     . ARG A 1 405 ? 29.95367  24.43629  2.31815  1.000 97.80974  ? 300  ARG A H     1 
ATOM   5488 H  HA    . ARG A 1 405 ? 31.15276  23.61523  0.16977  1.000 101.63795 ? 300  ARG A HA    1 
ATOM   5489 H  HB2   . ARG A 1 405 ? 29.31080  25.26112  0.43215  1.000 102.27755 ? 300  ARG A HB2   1 
ATOM   5490 H  HB3   . ARG A 1 405 ? 30.49617  26.31956  0.43075  1.000 102.27755 ? 300  ARG A HB3   1 
ATOM   5491 H  HG2   . ARG A 1 405 ? 30.24168  26.37220  -1.70084 1.000 106.66714 ? 300  ARG A HG2   1 
ATOM   5492 H  HG3   . ARG A 1 405 ? 30.96246  24.95606  -1.72149 1.000 106.66714 ? 300  ARG A HG3   1 
ATOM   5493 H  HD2   . ARG A 1 405 ? 28.93325  24.88255  -2.90508 1.000 112.55163 ? 300  ARG A HD2   1 
ATOM   5494 H  HD3   . ARG A 1 405 ? 28.89894  23.88544  -1.66814 1.000 112.55163 ? 300  ARG A HD3   1 
ATOM   5495 H  HE    . ARG A 1 405 ? 27.82887  26.09102  -0.84375 1.000 114.79367 ? 300  ARG A HE    1 
ATOM   5496 H  HH11  . ARG A 1 405 ? 26.91107  23.85216  -3.11852 1.000 127.06599 ? 300  ARG A HH11  1 
ATOM   5497 H  HH12  . ARG A 1 405 ? 25.44970  24.11710  -3.00451 1.000 127.06599 ? 300  ARG A HH12  1 
ATOM   5498 H  HH21  . ARG A 1 405 ? 25.62005  26.45507  -0.69318 1.000 118.52611 ? 300  ARG A HH21  1 
ATOM   5499 H  HH22  . ARG A 1 405 ? 24.67084  25.68460  -1.54416 1.000 118.52611 ? 300  ARG A HH22  1 
ATOM   5500 N  N     . LYS A 1 406 ? 32.83059  25.83415  1.77571  1.000 86.34601  ? 301  LYS A N     1 
ATOM   5501 C  CA    . LYS A 1 406 ? 34.16787  26.40261  1.91173  1.000 88.71664  ? 301  LYS A CA    1 
ATOM   5502 C  C     . LYS A 1 406 ? 35.19893  25.32137  2.20951  1.000 88.39572  ? 301  LYS A C     1 
ATOM   5503 O  O     . LYS A 1 406 ? 36.28375  25.30643  1.61602  1.000 93.89031  ? 301  LYS A O     1 
ATOM   5504 C  CB    . LYS A 1 406 ? 34.17504  27.46538  3.01121  1.000 85.87177  ? 301  LYS A CB    1 
ATOM   5505 H  H     . LYS A 1 406 ? 32.25616  26.12913  2.34370  1.000 103.65842 ? 301  LYS A H     1 
ATOM   5506 H  HA    . LYS A 1 406 ? 34.41241  26.83025  1.07614  1.000 106.50319 ? 301  LYS A HA    1 
ATOM   5507 N  N     . ILE A 1 407 ? 34.87830  24.40655  3.12644  1.000 88.40628  ? 302  ILE A N     1 
ATOM   5508 C  CA    . ILE A 1 407 ? 35.81467  23.34070  3.47449  1.000 87.33592  ? 302  ILE A CA    1 
ATOM   5509 C  C     . ILE A 1 407 ? 36.10252  22.47470  2.25469  1.000 91.72352  ? 302  ILE A C     1 
ATOM   5510 O  O     . ILE A 1 407 ? 37.25613  22.13265  1.96815  1.000 95.36530  ? 302  ILE A O     1 
ATOM   5511 C  CB    . ILE A 1 407 ? 35.26083  22.50081  4.64034  1.000 83.27240  ? 302  ILE A CB    1 
ATOM   5512 C  CG1   . ILE A 1 407 ? 35.07371  23.36873  5.88760  1.000 84.99860  ? 302  ILE A CG1   1 
ATOM   5513 C  CG2   . ILE A 1 407 ? 36.19126  21.33188  4.94680  1.000 83.36052  ? 302  ILE A CG2   1 
ATOM   5514 C  CD1   . ILE A 1 407 ? 34.24081  22.71237  6.97385  1.000 78.25976  ? 302  ILE A CD1   1 
ATOM   5515 H  H     . ILE A 1 407 ? 34.13370  24.38165  3.55602  1.000 106.13075 ? 302  ILE A H     1 
ATOM   5516 H  HA    . ILE A 1 407 ? 36.64879  23.74332  3.76266  1.000 104.84632 ? 302  ILE A HA    1 
ATOM   5517 H  HB    . ILE A 1 407 ? 34.39635  22.15025  4.37448  1.000 99.97010  ? 302  ILE A HB    1 
ATOM   5518 H  HG12  . ILE A 1 407 ? 35.94597  23.56659  6.26300  1.000 102.04153 ? 302  ILE A HG12  1 
ATOM   5519 H  HG13  . ILE A 1 407 ? 34.62877  24.19144  5.63058  1.000 102.04153 ? 302  ILE A HG13  1 
ATOM   5520 H  HG21  . ILE A 1 407 ? 35.86700  20.86832  5.73475  1.000 100.07584 ? 302  ILE A HG21  1 
ATOM   5521 H  HG22  . ILE A 1 407 ? 36.20002  20.72786  4.18786  1.000 100.07584 ? 302  ILE A HG22  1 
ATOM   5522 H  HG23  . ILE A 1 407 ? 37.08473  21.67331  5.10815  1.000 100.07584 ? 302  ILE A HG23  1 
ATOM   5523 H  HD11  . ILE A 1 407 ? 34.11032  23.34507  7.69743  1.000 93.95493  ? 302  ILE A HD11  1 
ATOM   5524 H  HD12  . ILE A 1 407 ? 33.38314  22.45416  6.60153  1.000 93.95493  ? 302  ILE A HD12  1 
ATOM   5525 H  HD13  . ILE A 1 407 ? 34.70917  21.92826  7.30052  1.000 93.95493  ? 302  ILE A HD13  1 
ATOM   5526 N  N     . ILE A 1 408 ? 35.05374  22.10793  1.51811  1.000 93.51619  ? 303  ILE A N     1 
ATOM   5527 C  CA    . ILE A 1 408 ? 35.21941  21.22108  0.37088  1.000 96.34490  ? 303  ILE A CA    1 
ATOM   5528 C  C     . ILE A 1 408 ? 36.03990  21.90512  -0.71590 1.000 97.57124  ? 303  ILE A C     1 
ATOM   5529 O  O     . ILE A 1 408 ? 37.01823  21.34344  -1.22315 1.000 98.51981  ? 303  ILE A O     1 
ATOM   5530 C  CB    . ILE A 1 408 ? 33.84185  20.77290  -0.15181 1.000 93.21532  ? 303  ILE A CB    1 
ATOM   5531 C  CG1   . ILE A 1 408 ? 33.13501  19.91575  0.90233  1.000 92.02626  ? 303  ILE A CG1   1 
ATOM   5532 C  CG2   . ILE A 1 408 ? 33.97871  19.99679  -1.45540 1.000 93.21727  ? 303  ILE A CG2   1 
ATOM   5533 C  CD1   . ILE A 1 408 ? 31.63334  19.85529  0.73922  1.000 90.71325  ? 303  ILE A CD1   1 
ATOM   5534 H  H     . ILE A 1 408 ? 34.24304  22.35687  1.66088  1.000 112.26265 ? 303  ILE A H     1 
ATOM   5535 H  HA    . ILE A 1 408 ? 35.70638  20.43120  0.65345  1.000 115.65710 ? 303  ILE A HA    1 
ATOM   5536 H  HB    . ILE A 1 408 ? 33.31165  21.56651  -0.32496 1.000 111.90160 ? 303  ILE A HB    1 
ATOM   5537 H  HG12  . ILE A 1 408 ? 33.47480  19.00905  0.84471  1.000 110.47472 ? 303  ILE A HG12  1 
ATOM   5538 H  HG13  . ILE A 1 408 ? 33.32188  20.28495  1.77964  1.000 110.47472 ? 303  ILE A HG13  1 
ATOM   5539 H  HG21  . ILE A 1 408 ? 33.09585  19.73897  -1.76362 1.000 111.90394 ? 303  ILE A HG21  1 
ATOM   5540 H  HG22  . ILE A 1 408 ? 34.40762  20.56263  -2.11628 1.000 111.90394 ? 303  ILE A HG22  1 
ATOM   5541 H  HG23  . ILE A 1 408 ? 34.51777  19.20606  -1.29707 1.000 111.90394 ? 303  ILE A HG23  1 
ATOM   5542 H  HD11  . ILE A 1 408 ? 31.27454  19.20047  1.35838  1.000 108.89911 ? 303  ILE A HD11  1 
ATOM   5543 H  HD12  . ILE A 1 408 ? 31.25955  20.72993  0.92941  1.000 108.89911 ? 303  ILE A HD12  1 
ATOM   5544 H  HD13  . ILE A 1 408 ? 31.42482  19.59757  -0.17238 1.000 108.89911 ? 303  ILE A HD13  1 
ATOM   5545 N  N     . ARG A 1 409 ? 35.65527  23.12909  -1.08783 1.000 94.86682  ? 304  ARG A N     1 
ATOM   5546 C  CA    . ARG A 1 409 ? 36.34244  23.82342  -2.17271 1.000 96.15336  ? 304  ARG A CA    1 
ATOM   5547 C  C     . ARG A 1 409 ? 37.83571  23.94723  -1.89550 1.000 97.24569  ? 304  ARG A C     1 
ATOM   5548 O  O     . ARG A 1 409 ? 38.65761  23.80913  -2.80914 1.000 102.53502 ? 304  ARG A O     1 
ATOM   5549 C  CB    . ARG A 1 409 ? 35.72115  25.20415  -2.38433 1.000 94.64097  ? 304  ARG A CB    1 
ATOM   5550 H  H     . ARG A 1 409 ? 35.00895  23.57139  -0.73253 1.000 113.88340 ? 304  ARG A H     1 
ATOM   5551 H  HA    . ARG A 1 409 ? 36.23157  23.31213  -2.98953 1.000 115.42724 ? 304  ARG A HA    1 
ATOM   5552 N  N     . SER A 1 410 ? 38.20613  24.20497  -0.64572 1.000 97.18906  ? 305  SER A N     1 
ATOM   5553 C  CA    . SER A 1 410 ? 39.61116  24.32703  -0.27405 1.000 97.05864  ? 305  SER A CA    1 
ATOM   5554 C  C     . SER A 1 410 ? 40.29501  22.96459  -0.27836 1.000 102.99227 ? 305  SER A C     1 
ATOM   5555 O  O     . SER A 1 410 ? 40.18706  22.20341  0.68334  1.000 101.95433 ? 305  SER A O     1 
ATOM   5556 C  CB    . SER A 1 410 ? 39.74479  24.97416  1.10401  1.000 97.57497  ? 305  SER A CB    1 
ATOM   5557 O  OG    . SER A 1 410 ? 39.13272  26.25148  1.12434  1.000 104.43042 ? 305  SER A OG    1 
ATOM   5558 H  H     . SER A 1 410 ? 37.65969  24.31407  0.00934  1.000 116.67009 ? 305  SER A H     1 
ATOM   5559 H  HA    . SER A 1 410 ? 40.06163  24.89432  -0.91916 1.000 116.51358 ? 305  SER A HA    1 
ATOM   5560 H  HB2   . SER A 1 410 ? 39.31322  24.40703  1.76205  1.000 117.13318 ? 305  SER A HB2   1 
ATOM   5561 H  HB3   . SER A 1 410 ? 40.68613  25.07199  1.31666  1.000 117.13318 ? 305  SER A HB3   1 
ATOM   5562 H  HG    . SER A 1 410 ? 39.18191  26.58139  1.89527  1.000 125.35972 ? 305  SER A HG    1 
HETATM 5563 NA NA    . NA  B 2 .   ? 23.41485  8.71730   16.37501 1.000 56.86166  ? 1201 NA  A NA    1 
HETATM 5564 C  C1    . CLR C 3 .   ? 38.43635  -10.57036 22.13736 1.000 78.80836  ? 1202 CLR A C1    1 
HETATM 5565 C  C2    . CLR C 3 .   ? 38.03713  -12.02379 22.36166 1.000 78.60529  ? 1202 CLR A C2    1 
HETATM 5566 C  C3    . CLR C 3 .   ? 38.28639  -12.42363 23.80517 1.000 76.89591  ? 1202 CLR A C3    1 
HETATM 5567 C  C4    . CLR C 3 .   ? 37.50406  -11.48962 24.73011 1.000 71.47708  ? 1202 CLR A C4    1 
HETATM 5568 C  C5    . CLR C 3 .   ? 37.82916  -10.04259 24.48662 1.000 71.65558  ? 1202 CLR A C5    1 
HETATM 5569 C  C6    . CLR C 3 .   ? 38.20370  -9.25391  25.49396 1.000 70.92113  ? 1202 CLR A C6    1 
HETATM 5570 C  C7    . CLR C 3 .   ? 38.46382  -7.78742  25.38741 1.000 75.42151  ? 1202 CLR A C7    1 
HETATM 5571 C  C8    . CLR C 3 .   ? 38.05590  -7.20009  24.03964 1.000 72.94838  ? 1202 CLR A C8    1 
HETATM 5572 C  C9    . CLR C 3 .   ? 38.42432  -8.17659  22.91249 1.000 76.43685  ? 1202 CLR A C9    1 
HETATM 5573 C  C10   . CLR C 3 .   ? 37.72084  -9.55342  23.05393 1.000 75.75482  ? 1202 CLR A C10   1 
HETATM 5574 C  C11   . CLR C 3 .   ? 38.23927  -7.53091  21.53489 1.000 75.38747  ? 1202 CLR A C11   1 
HETATM 5575 C  C12   . CLR C 3 .   ? 38.90631  -6.15872  21.38791 1.000 74.36647  ? 1202 CLR A C12   1 
HETATM 5576 C  C13   . CLR C 3 .   ? 38.44512  -5.18163  22.46487 1.000 74.33089  ? 1202 CLR A C13   1 
HETATM 5577 C  C14   . CLR C 3 .   ? 38.74979  -5.86663  23.80833 1.000 75.25627  ? 1202 CLR A C14   1 
HETATM 5578 C  C15   . CLR C 3 .   ? 38.57682  -4.76617  24.84765 1.000 76.24671  ? 1202 CLR A C15   1 
HETATM 5579 C  C16   . CLR C 3 .   ? 39.04117  -3.49738  24.11020 1.000 78.65787  ? 1202 CLR A C16   1 
HETATM 5580 C  C17   . CLR C 3 .   ? 39.26085  -3.87143  22.61729 1.000 75.70933  ? 1202 CLR A C17   1 
HETATM 5581 C  C18   . CLR C 3 .   ? 36.96794  -4.83653  22.32609 1.000 73.95062  ? 1202 CLR A C18   1 
HETATM 5582 C  C19   . CLR C 3 .   ? 36.23191  -9.48452  22.68166 1.000 75.70829  ? 1202 CLR A C19   1 
HETATM 5583 C  C20   . CLR C 3 .   ? 38.96029  -2.70121  21.67020 1.000 78.43900  ? 1202 CLR A C20   1 
HETATM 5584 C  C21   . CLR C 3 .   ? 38.93994  -3.10901  20.19745 1.000 79.61219  ? 1202 CLR A C21   1 
HETATM 5585 C  C22   . CLR C 3 .   ? 39.96890  -1.56828  21.89313 1.000 82.00180  ? 1202 CLR A C22   1 
HETATM 5586 C  C23   . CLR C 3 .   ? 39.66893  -0.27855  21.13502 1.000 83.66856  ? 1202 CLR A C23   1 
HETATM 5587 C  C24   . CLR C 3 .   ? 40.52062  0.88343   21.63036 1.000 87.73080  ? 1202 CLR A C24   1 
HETATM 5588 C  C25   . CLR C 3 .   ? 40.20849  2.22964   20.97598 1.000 95.71474  ? 1202 CLR A C25   1 
HETATM 5589 C  C26   . CLR C 3 .   ? 40.90301  2.33030   19.62063 1.000 92.71282  ? 1202 CLR A C26   1 
HETATM 5590 C  C27   . CLR C 3 .   ? 40.59423  3.39964   21.86857 1.000 99.59544  ? 1202 CLR A C27   1 
HETATM 5591 O  O1    . CLR C 3 .   ? 37.91986  -13.77977 23.96248 1.000 75.56329  ? 1202 CLR A O1    1 
HETATM 5592 H  H11   . CLR C 3 .   ? 38.26049  -10.33429 21.21310 1.000 94.61325  ? 1202 CLR A H11   1 
HETATM 5593 H  H12   . CLR C 3 .   ? 39.39416  -10.48355 22.26368 1.000 94.61325  ? 1202 CLR A H12   1 
HETATM 5594 H  H21   . CLR C 3 .   ? 38.54181  -12.59506 21.76179 1.000 94.36956  ? 1202 CLR A H21   1 
HETATM 5595 H  H22   . CLR C 3 .   ? 37.10107  -12.14155 22.13620 1.000 94.36956  ? 1202 CLR A H22   1 
HETATM 5596 H  H3    . CLR C 3 .   ? 39.22969  -12.31348 24.00253 1.000 92.31831  ? 1202 CLR A H3    1 
HETATM 5597 H  H41   . CLR C 3 .   ? 36.55164  -11.62542 24.60625 1.000 85.81572  ? 1202 CLR A H41   1 
HETATM 5598 H  H42   . CLR C 3 .   ? 37.69642  -11.70600 25.65589 1.000 85.81572  ? 1202 CLR A H42   1 
HETATM 5599 H  H6    . CLR C 3 .   ? 38.31553  -9.63434  26.33518 1.000 85.14858  ? 1202 CLR A H6    1 
HETATM 5600 H  H71   . CLR C 3 .   ? 39.40494  -7.61855  25.55070 1.000 90.54903  ? 1202 CLR A H71   1 
HETATM 5601 H  H72   . CLR C 3 .   ? 37.99686  -7.32865  26.10322 1.000 90.54903  ? 1202 CLR A H72   1 
HETATM 5602 H  H8    . CLR C 3 .   ? 37.09655  -7.05678  24.04124 1.000 87.58127  ? 1202 CLR A H8    1 
HETATM 5603 H  H9    . CLR C 3 .   ? 39.37353  -8.35059  23.01057 1.000 91.76743  ? 1202 CLR A H9    1 
HETATM 5604 H  H111  . CLR C 3 .   ? 37.29398  -7.43393  21.34014 1.000 90.50818  ? 1202 CLR A H111  1 
HETATM 5605 H  H112  . CLR C 3 .   ? 38.58993  -8.11685  20.84597 1.000 90.50818  ? 1202 CLR A H112  1 
HETATM 5606 H  H121  . CLR C 3 .   ? 38.70973  -5.78521  20.51455 1.000 89.28298  ? 1202 CLR A H121  1 
HETATM 5607 H  H122  . CLR C 3 .   ? 39.87078  -6.25108  21.43441 1.000 89.28298  ? 1202 CLR A H122  1 
HETATM 5608 H  H14   . CLR C 3 .   ? 39.69851  -6.06669  23.77995 1.000 90.35074  ? 1202 CLR A H14   1 
HETATM 5609 H  H151  . CLR C 3 .   ? 39.10820  -4.93591  25.64120 1.000 91.53926  ? 1202 CLR A H151  1 
HETATM 5610 H  H152  . CLR C 3 .   ? 37.65576  -4.69382  25.14314 1.000 91.53926  ? 1202 CLR A H152  1 
HETATM 5611 H  H161  . CLR C 3 .   ? 38.38152  -2.79106  24.19306 1.000 94.43267  ? 1202 CLR A H161  1 
HETATM 5612 H  H162  . CLR C 3 .   ? 39.85931  -3.15283  24.50115 1.000 94.43267  ? 1202 CLR A H162  1 
HETATM 5613 H  H17   . CLR C 3 .   ? 40.19616  -4.10012  22.49986 1.000 90.89442  ? 1202 CLR A H17   1 
HETATM 5614 H  H181  . CLR C 3 .   ? 36.76849  -3.99082  22.75726 1.000 88.78396  ? 1202 CLR A H181  1 
HETATM 5615 H  H182  . CLR C 3 .   ? 36.41346  -5.51973  22.73437 1.000 88.78396  ? 1202 CLR A H182  1 
HETATM 5616 H  H183  . CLR C 3 .   ? 36.71609  -4.76407  21.39216 1.000 88.78396  ? 1202 CLR A H183  1 
HETATM 5617 H  H191  . CLR C 3 .   ? 35.76523  -10.30171 22.91685 1.000 90.89316  ? 1202 CLR A H191  1 
HETATM 5618 H  H192  . CLR C 3 .   ? 35.78151  -8.75647  23.13771 1.000 90.89316  ? 1202 CLR A H192  1 
HETATM 5619 H  H193  . CLR C 3 .   ? 36.10622  -9.34713  21.72971 1.000 90.89316  ? 1202 CLR A H193  1 
HETATM 5620 H  H20   . CLR C 3 .   ? 38.08569  -2.35623  21.90887 1.000 94.17001  ? 1202 CLR A H20   1 
HETATM 5621 H  H211  . CLR C 3 .   ? 38.20349  -3.70975  20.00342 1.000 95.57784  ? 1202 CLR A H211  1 
HETATM 5622 H  H212  . CLR C 3 .   ? 38.84452  -2.33919  19.61506 1.000 95.57784  ? 1202 CLR A H212  1 
HETATM 5623 H  H213  . CLR C 3 .   ? 39.75755  -3.56392  19.94157 1.000 95.57784  ? 1202 CLR A H213  1 
HETATM 5624 H  H221  . CLR C 3 .   ? 40.01600  -1.37624  22.84277 1.000 98.44538  ? 1202 CLR A H221  1 
HETATM 5625 H  H222  . CLR C 3 .   ? 40.85192  -1.88503  21.64644 1.000 98.44538  ? 1202 CLR A H222  1 
HETATM 5626 H  H231  . CLR C 3 .   ? 39.82173  -0.41325  20.18665 1.000 100.44548 ? 1202 CLR A H231  1 
HETATM 5627 H  H232  . CLR C 3 .   ? 38.72929  -0.05593  21.22680 1.000 100.44548 ? 1202 CLR A H232  1 
HETATM 5628 H  H241  . CLR C 3 .   ? 41.45715  0.67551   21.48692 1.000 105.32017 ? 1202 CLR A H241  1 
HETATM 5629 H  H242  . CLR C 3 .   ? 40.41352  0.96999   22.59054 1.000 105.32017 ? 1202 CLR A H242  1 
HETATM 5630 H  H25   . CLR C 3 .   ? 39.25237  2.27692   20.81943 1.000 114.90091 ? 1202 CLR A H25   1 
HETATM 5631 H  H261  . CLR C 3 .   ? 40.58465  1.65001   19.00682 1.000 111.29860 ? 1202 CLR A H261  1 
HETATM 5632 H  H262  . CLR C 3 .   ? 41.86296  2.21887   19.70410 1.000 111.29860 ? 1202 CLR A H262  1 
HETATM 5633 H  H263  . CLR C 3 .   ? 40.74650  3.19231   19.20430 1.000 111.29860 ? 1202 CLR A H263  1 
HETATM 5634 H  H271  . CLR C 3 .   ? 41.54496  3.38446   22.06037 1.000 119.55775 ? 1202 CLR A H271  1 
HETATM 5635 H  H272  . CLR C 3 .   ? 40.11346  3.36070   22.71014 1.000 119.55775 ? 1202 CLR A H272  1 
HETATM 5636 H  H273  . CLR C 3 .   ? 40.38437  4.24263   21.43704 1.000 119.55775 ? 1202 CLR A H273  1 
HETATM 5637 H  H1    . CLR C 3 .   ? 38.13796  -14.02280 24.74725 1.000 90.71916  ? 1202 CLR A H1    1 
HETATM 5638 C  C1    . CLR D 3 .   ? 8.24437   -10.76562 13.93580 1.000 69.05056  ? 1203 CLR A C1    1 
HETATM 5639 C  C2    . CLR D 3 .   ? 8.30114   -12.28727 13.97753 1.000 68.21018  ? 1203 CLR A C2    1 
HETATM 5640 C  C3    . CLR D 3 .   ? 6.93353   -12.88000 13.68657 1.000 70.70734  ? 1203 CLR A C3    1 
HETATM 5641 C  C4    . CLR D 3 .   ? 6.43733   -12.38208 12.32908 1.000 71.27751  ? 1203 CLR A C4    1 
HETATM 5642 C  C5    . CLR D 3 .   ? 6.44717   -10.88309 12.23335 1.000 75.17419  ? 1203 CLR A C5    1 
HETATM 5643 C  C6    . CLR D 3 .   ? 5.35343   -10.22449 11.85164 1.000 78.13567  ? 1203 CLR A C6    1 
HETATM 5644 C  C7    . CLR D 3 .   ? 5.27597   -8.75000  11.63200 1.000 78.68507  ? 1203 CLR A C7    1 
HETATM 5645 C  C8    . CLR D 3 .   ? 6.64734   -8.08153  11.63045 1.000 77.96986  ? 1203 CLR A C8    1 
HETATM 5646 C  C9    . CLR D 3 .   ? 7.50594   -8.66091  12.76536 1.000 73.65713  ? 1203 CLR A C9    1 
HETATM 5647 C  C10   . CLR D 3 .   ? 7.74718   -10.18559 12.59522 1.000 72.40153  ? 1203 CLR A C10   1 
HETATM 5648 C  C11   . CLR D 3 .   ? 8.79238   -7.85464  12.97319 1.000 73.18889  ? 1203 CLR A C11   1 
HETATM 5649 C  C12   . CLR D 3 .   ? 8.59701   -6.33362  13.03084 1.000 73.64025  ? 1203 CLR A C12   1 
HETATM 5650 C  C13   . CLR D 3 .   ? 7.84678   -5.80967  11.81250 1.000 76.87107  ? 1203 CLR A C13   1 
HETATM 5651 C  C14   . CLR D 3 .   ? 6.51476   -6.57642  11.79549 1.000 80.87545  ? 1203 CLR A C14   1 
HETATM 5652 C  C15   . CLR D 3 .   ? 5.62732   -5.81964  10.81640 1.000 84.14705  ? 1203 CLR A C15   1 
HETATM 5653 C  C16   . CLR D 3 .   ? 6.10343   -4.36248  10.94070 1.000 81.02249  ? 1203 CLR A C16   1 
HETATM 5654 C  C17   . CLR D 3 .   ? 7.33278   -4.34834  11.89316 1.000 75.40593  ? 1203 CLR A C17   1 
HETATM 5655 C  C18   . CLR D 3 .   ? 8.64234   -6.02278  10.52935 1.000 74.60302  ? 1203 CLR A C18   1 
HETATM 5656 C  C19   . CLR D 3 .   ? 8.77446   -10.48509 11.49166 1.000 75.92787  ? 1203 CLR A C19   1 
HETATM 5657 C  C20   . CLR D 3 .   ? 8.28884   -3.18471  11.58911 1.000 72.44173  ? 1203 CLR A C20   1 
HETATM 5658 C  C21   . CLR D 3 .   ? 9.62473   -3.30239  12.32051 1.000 71.49611  ? 1203 CLR A C21   1 
HETATM 5659 C  C22   . CLR D 3 .   ? 7.61061   -1.85146  11.93598 1.000 71.92350  ? 1203 CLR A C22   1 
HETATM 5660 C  C23   . CLR D 3 .   ? 8.30857   -0.59127  11.42770 1.000 73.24147  ? 1203 CLR A C23   1 
HETATM 5661 C  C24   . CLR D 3 .   ? 7.94990   0.64159   12.25233 1.000 71.70682  ? 1203 CLR A C24   1 
HETATM 5662 C  C25   . CLR D 3 .   ? 8.83115   1.86666   11.99735 1.000 71.32265  ? 1203 CLR A C25   1 
HETATM 5663 C  C26   . CLR D 3 .   ? 8.78269   2.81324   13.19408 1.000 73.05919  ? 1203 CLR A C26   1 
HETATM 5664 C  C27   . CLR D 3 .   ? 8.43755   2.60064   10.72320 1.000 79.27495  ? 1203 CLR A C27   1 
HETATM 5665 O  O1    . CLR D 3 .   ? 7.02880   -14.28908 13.73329 1.000 73.15363  ? 1203 CLR A O1    1 
HETATM 5666 H  H11   . CLR D 3 .   ? 9.12712   -10.40998 14.12333 1.000 82.90388  ? 1203 CLR A H11   1 
HETATM 5667 H  H12   . CLR D 3 .   ? 7.66612   -10.45010 14.64783 1.000 82.90388  ? 1203 CLR A H12   1 
HETATM 5668 H  H21   . CLR D 3 .   ? 8.61404   -12.57560 14.84923 1.000 81.89543  ? 1203 CLR A H21   1 
HETATM 5669 H  H22   . CLR D 3 .   ? 8.94988   -12.60473 13.33003 1.000 81.89543  ? 1203 CLR A H22   1 
HETATM 5670 H  H3    . CLR D 3 .   ? 6.31719   -12.56562 14.36641 1.000 84.89203  ? 1203 CLR A H3    1 
HETATM 5671 H  H41   . CLR D 3 .   ? 6.99092   -12.74818 11.62168 1.000 85.57623  ? 1203 CLR A H41   1 
HETATM 5672 H  H42   . CLR D 3 .   ? 5.53614   -12.70363 12.16979 1.000 85.57623  ? 1203 CLR A H42   1 
HETATM 5673 H  H6    . CLR D 3 .   ? 4.57215   -10.70799 11.70767 1.000 93.80602  ? 1203 CLR A H6    1 
HETATM 5674 H  H71   . CLR D 3 .   ? 4.71299   -8.35341  12.31513 1.000 94.46530  ? 1203 CLR A H71   1 
HETATM 5675 H  H72   . CLR D 3 .   ? 4.81897   -8.57435  10.79462 1.000 94.46530  ? 1203 CLR A H72   1 
HETATM 5676 H  H8    . CLR D 3 .   ? 7.07733   -8.25710  10.77887 1.000 93.60705  ? 1203 CLR A H8    1 
HETATM 5677 H  H9    . CLR D 3 .   ? 6.98896   -8.54935  13.57849 1.000 88.43178  ? 1203 CLR A H9    1 
HETATM 5678 H  H111  . CLR D 3 .   ? 9.42191   -8.05284  12.26234 1.000 87.86988  ? 1203 CLR A H111  1 
HETATM 5679 H  H112  . CLR D 3 .   ? 9.22661   -8.13596  13.79368 1.000 87.86988  ? 1203 CLR A H112  1 
HETATM 5680 H  H121  . CLR D 3 .   ? 9.45741   -5.88962  13.08977 1.000 88.41151  ? 1203 CLR A H121  1 
HETATM 5681 H  H122  . CLR D 3 .   ? 8.10918   -6.09099  13.83338 1.000 88.41151  ? 1203 CLR A H122  1 
HETATM 5682 H  H14   . CLR D 3 .   ? 6.12559   -6.42496  12.67100 1.000 97.09375  ? 1203 CLR A H14   1 
HETATM 5683 H  H151  . CLR D 3 .   ? 4.68816   -5.91070  11.04134 1.000 101.01967 ? 1203 CLR A H151  1 
HETATM 5684 H  H152  . CLR D 3 .   ? 5.72749   -6.15389  9.91133  1.000 101.01967 ? 1203 CLR A H152  1 
HETATM 5685 H  H161  . CLR D 3 .   ? 6.33876   -4.00223  10.07136 1.000 97.27020  ? 1203 CLR A H161  1 
HETATM 5686 H  H162  . CLR D 3 .   ? 5.39488   -3.79749  11.28660 1.000 97.27020  ? 1203 CLR A H162  1 
HETATM 5687 H  H17   . CLR D 3 .   ? 7.02071   -4.21777  12.80226 1.000 90.53033  ? 1203 CLR A H17   1 
HETATM 5688 H  H181  . CLR D 3 .   ? 8.14809   -5.70197  9.75883  1.000 89.56684  ? 1203 CLR A H181  1 
HETATM 5689 H  H182  . CLR D 3 .   ? 8.83296   -6.96405  10.39306 1.000 89.56684  ? 1203 CLR A H182  1 
HETATM 5690 H  H183  . CLR D 3 .   ? 9.48711   -5.54729  10.56334 1.000 89.56684  ? 1203 CLR A H183  1 
HETATM 5691 H  H191  . CLR D 3 .   ? 8.79433   -11.42842 11.26660 1.000 91.15666  ? 1203 CLR A H191  1 
HETATM 5692 H  H192  . CLR D 3 .   ? 8.57553   -10.00036 10.67535 1.000 91.15666  ? 1203 CLR A H192  1 
HETATM 5693 H  H193  . CLR D 3 .   ? 9.67258   -10.23615 11.76056 1.000 91.15666  ? 1203 CLR A H193  1 
HETATM 5694 H  H20   . CLR D 3 .   ? 8.45683   -3.18531  10.63377 1.000 86.97329  ? 1203 CLR A H20   1 
HETATM 5695 H  H211  . CLR D 3 .   ? 10.13126  -4.07205  12.01727 1.000 85.83854  ? 1203 CLR A H211  1 
HETATM 5696 H  H212  . CLR D 3 .   ? 10.17926  -2.51913  12.17946 1.000 85.83854  ? 1203 CLR A H212  1 
HETATM 5697 H  H213  . CLR D 3 .   ? 9.50051   -3.39852  13.27771 1.000 85.83854  ? 1203 CLR A H213  1 
HETATM 5698 H  H221  . CLR D 3 .   ? 6.70428   -1.86982  11.59082 1.000 86.35142  ? 1203 CLR A H221  1 
HETATM 5699 H  H222  . CLR D 3 .   ? 7.52194   -1.79454  12.90024 1.000 86.35142  ? 1203 CLR A H222  1 
HETATM 5700 H  H231  . CLR D 3 .   ? 9.26951   -0.72270  11.44243 1.000 87.93299  ? 1203 CLR A H231  1 
HETATM 5701 H  H232  . CLR D 3 .   ? 8.07228   -0.44007  10.49915 1.000 87.93299  ? 1203 CLR A H232  1 
HETATM 5702 H  H241  . CLR D 3 .   ? 7.99330   0.41675   13.19492 1.000 86.09140  ? 1203 CLR A H241  1 
HETATM 5703 H  H242  . CLR D 3 .   ? 7.02573   0.88078   12.08032 1.000 86.09140  ? 1203 CLR A H242  1 
HETATM 5704 H  H25   . CLR D 3 .   ? 9.74631   1.56077   11.89825 1.000 85.63039  ? 1203 CLR A H25   1 
HETATM 5705 H  H261  . CLR D 3 .   ? 9.16616   2.40483   13.98595 1.000 87.71424  ? 1203 CLR A H261  1 
HETATM 5706 H  H262  . CLR D 3 .   ? 7.87156   3.06585   13.41067 1.000 87.71424  ? 1203 CLR A H262  1 
HETATM 5707 H  H263  . CLR D 3 .   ? 9.27653   3.63005   13.02130 1.000 87.71424  ? 1203 CLR A H263  1 
HETATM 5708 H  H271  . CLR D 3 .   ? 7.52725   2.92982   10.78554 1.000 95.17315  ? 1203 CLR A H271  1 
HETATM 5709 H  H272  . CLR D 3 .   ? 8.49543   2.00950   9.95631  1.000 95.17315  ? 1203 CLR A H272  1 
HETATM 5710 H  H273  . CLR D 3 .   ? 9.02475   3.35718   10.56913 1.000 95.17315  ? 1203 CLR A H273  1 
HETATM 5711 H  H1    . CLR D 3 .   ? 6.24119   -14.60782 13.70913 1.000 87.82758  ? 1203 CLR A H1    1 
HETATM 5712 C  C1    . CLR E 3 .   ? 3.23721   -7.98932  22.02262 1.000 72.31923  ? 1204 CLR A C1    1 
HETATM 5713 C  C2    . CLR E 3 .   ? 3.07824   -9.50364  21.96280 1.000 67.81881  ? 1204 CLR A C2    1 
HETATM 5714 C  C3    . CLR E 3 .   ? 2.06104   -9.89233  20.90498 1.000 71.97069  ? 1204 CLR A C3    1 
HETATM 5715 C  C4    . CLR E 3 .   ? 2.47693   -9.31623  19.55069 1.000 69.74069  ? 1204 CLR A C4    1 
HETATM 5716 C  C5    . CLR E 3 .   ? 2.72087   -7.83335  19.60593 1.000 77.34303  ? 1204 CLR A C5    1 
HETATM 5717 C  C6    . CLR E 3 .   ? 2.10814   -7.01328  18.75073 1.000 74.14736  ? 1204 CLR A C6    1 
HETATM 5718 C  C7    . CLR E 3 .   ? 2.37283   -5.54885  18.63320 1.000 71.79456  ? 1204 CLR A C7    1 
HETATM 5719 C  C8    . CLR E 3 .   ? 3.57554   -5.09688  19.45552 1.000 70.82644  ? 1204 CLR A C8    1 
HETATM 5720 C  C9    . CLR E 3 .   ? 3.56593   -5.79310  20.82505 1.000 73.66266  ? 1204 CLR A C9    1 
HETATM 5721 C  C10   . CLR E 3 .   ? 3.66498   -7.33932  20.68949 1.000 76.95005  ? 1204 CLR A C10   1 
HETATM 5722 C  C11   . CLR E 3 .   ? 4.60138   -5.18342  21.77921 1.000 73.95158  ? 1204 CLR A C11   1 
HETATM 5723 C  C12   . CLR E 3 .   ? 4.60770   -3.64936  21.83629 1.000 74.59867  ? 1204 CLR A C12   1 
HETATM 5724 C  C13   . CLR E 3 .   ? 4.74760   -3.02933  20.44985 1.000 75.01493  ? 1204 CLR A C13   1 
HETATM 5725 C  C14   . CLR E 3 .   ? 3.56503   -3.58782  19.64062 1.000 74.58688  ? 1204 CLR A C14   1 
HETATM 5726 C  C15   . CLR E 3 .   ? 3.47043   -2.71607  18.39689 1.000 75.80347  ? 1204 CLR A C15   1 
HETATM 5727 C  C16   . CLR E 3 .   ? 3.99190   -1.34835  18.86691 1.000 82.99578  ? 1204 CLR A C16   1 
HETATM 5728 C  C17   . CLR E 3 .   ? 4.49332   -1.50115  20.33068 1.000 75.65808  ? 1204 CLR A C17   1 
HETATM 5729 C  C18   . CLR E 3 .   ? 6.09014   -3.38261  19.82001 1.000 69.36449  ? 1204 CLR A C18   1 
HETATM 5730 C  C19   . CLR E 3 .   ? 5.08791   -7.79893  20.32922 1.000 74.82277  ? 1204 CLR A C19   1 
HETATM 5731 C  C20   . CLR E 3 .   ? 5.62999   -0.51983  20.66390 1.000 73.72732  ? 1204 CLR A C20   1 
HETATM 5732 C  C21   . CLR E 3 .   ? 6.19928   -0.73405  22.06581 1.000 78.86973  ? 1204 CLR A C21   1 
HETATM 5733 C  C22   . CLR E 3 .   ? 5.16004   0.93200   20.49736 1.000 79.95757  ? 1204 CLR A C22   1 
HETATM 5734 C  C23   . CLR E 3 .   ? 6.23929   2.00744   20.62764 1.000 82.77169  ? 1204 CLR A C23   1 
HETATM 5735 C  C24   . CLR E 3 .   ? 5.64128   3.40892   20.72284 1.000 83.21420  ? 1204 CLR A C24   1 
HETATM 5736 C  C25   . CLR E 3 .   ? 5.76131   4.29112   19.47777 1.000 86.05037  ? 1204 CLR A C25   1 
HETATM 5737 C  C26   . CLR E 3 .   ? 4.75578   5.43837   19.56924 1.000 95.28926  ? 1204 CLR A C26   1 
HETATM 5738 C  C27   . CLR E 3 .   ? 5.56860   3.52790   18.17600 1.000 82.55422  ? 1204 CLR A C27   1 
HETATM 5739 O  O1    . CLR E 3 .   ? 1.95664   -11.30173 20.87269 1.000 69.98750  ? 1204 CLR A O1    1 
HETATM 5740 H  H11   . CLR E 3 .   ? 3.89087   -7.76620  22.70369 1.000 86.82629  ? 1204 CLR A H11   1 
HETATM 5741 H  H12   . CLR E 3 .   ? 2.39898   -7.59399  22.30894 1.000 86.82629  ? 1204 CLR A H12   1 
HETATM 5742 H  H21   . CLR E 3 .   ? 2.80242   -9.83444  22.83193 1.000 81.42579  ? 1204 CLR A H21   1 
HETATM 5743 H  H22   . CLR E 3 .   ? 3.93679   -9.91156  21.76945 1.000 81.42579  ? 1204 CLR A H22   1 
HETATM 5744 H  H3    . CLR E 3 .   ? 1.20854   -9.49879  21.14844 1.000 86.40805  ? 1204 CLR A H3    1 
HETATM 5745 H  H41   . CLR E 3 .   ? 3.28291   -9.75737  19.23975 1.000 83.73204  ? 1204 CLR A H41   1 
HETATM 5746 H  H42   . CLR E 3 .   ? 1.78948   -9.49872  18.89115 1.000 83.73204  ? 1204 CLR A H42   1 
HETATM 5747 H  H6    . CLR E 3 .   ? 1.46569   -7.36737  18.17908 1.000 89.02005  ? 1204 CLR A H6    1 
HETATM 5748 H  H71   . CLR E 3 .   ? 1.58133   -5.05791  18.90411 1.000 86.19669  ? 1204 CLR A H71   1 
HETATM 5749 H  H72   . CLR E 3 .   ? 2.50400   -5.32136  17.69942 1.000 86.19669  ? 1204 CLR A H72   1 
HETATM 5750 H  H8    . CLR E 3 .   ? 4.38386   -5.34176  18.97848 1.000 85.03495  ? 1204 CLR A H8    1 
HETATM 5751 H  H9    . CLR E 3 .   ? 2.70198   -5.60440  21.22366 1.000 88.43841  ? 1204 CLR A H9    1 
HETATM 5752 H  H111  . CLR E 3 .   ? 5.49051   -5.48036  21.52987 1.000 88.78511  ? 1204 CLR A H111  1 
HETATM 5753 H  H112  . CLR E 3 .   ? 4.45550   -5.51880  22.67762 1.000 88.78511  ? 1204 CLR A H112  1 
HETATM 5754 H  H121  . CLR E 3 .   ? 5.33546   -3.34014  22.39812 1.000 89.56162  ? 1204 CLR A H121  1 
HETATM 5755 H  H122  . CLR E 3 .   ? 3.79001   -3.32816  22.24753 1.000 89.56162  ? 1204 CLR A H122  1 
HETATM 5756 H  H14   . CLR E 3 .   ? 2.78094   -3.37197  20.16931 1.000 89.54747  ? 1204 CLR A H14   1 
HETATM 5757 H  H151  . CLR E 3 .   ? 2.55939   -2.65922  18.06875 1.000 91.00738  ? 1204 CLR A H151  1 
HETATM 5758 H  H152  . CLR E 3 .   ? 4.00361   -3.07255  17.66920 1.000 91.00738  ? 1204 CLR A H152  1 
HETATM 5759 H  H161  . CLR E 3 .   ? 4.70861   -1.03909  18.29107 1.000 99.63815  ? 1204 CLR A H161  1 
HETATM 5760 H  H162  . CLR E 3 .   ? 3.29214   -0.67871  18.81392 1.000 99.63815  ? 1204 CLR A H162  1 
HETATM 5761 H  H17   . CLR E 3 .   ? 3.75952   -1.29180  20.92951 1.000 90.83291  ? 1204 CLR A H17   1 
HETATM 5762 H  H181  . CLR E 3 .   ? 6.15760   -3.01918  18.92320 1.000 83.28061  ? 1204 CLR A H181  1 
HETATM 5763 H  H182  . CLR E 3 .   ? 6.20308   -4.34435  19.76344 1.000 83.28061  ? 1204 CLR A H182  1 
HETATM 5764 H  H183  . CLR E 3 .   ? 6.82313   -3.02465  20.34488 1.000 83.28061  ? 1204 CLR A H183  1 
HETATM 5765 H  H191  . CLR E 3 .   ? 5.11063   -8.73741  20.08498 1.000 89.83053  ? 1204 CLR A H191  1 
HETATM 5766 H  H192  . CLR E 3 .   ? 5.44709   -7.29938  19.57933 1.000 89.83053  ? 1204 CLR A H192  1 
HETATM 5767 H  H193  . CLR E 3 .   ? 5.70141   -7.68153  21.07134 1.000 89.83053  ? 1204 CLR A H193  1 
HETATM 5768 H  H20   . CLR E 3 .   ? 6.33171   -0.65956  20.00895 1.000 88.51600  ? 1204 CLR A H20   1 
HETATM 5769 H  H211  . CLR E 3 .   ? 6.59861   -1.61316  22.15856 1.000 94.68689  ? 1204 CLR A H211  1 
HETATM 5770 H  H212  . CLR E 3 .   ? 6.88632   -0.08225  22.27566 1.000 94.68689  ? 1204 CLR A H212  1 
HETATM 5771 H  H213  . CLR E 3 .   ? 5.51199   -0.65691  22.74594 1.000 94.68689  ? 1204 CLR A H213  1 
HETATM 5772 H  H221  . CLR E 3 .   ? 4.73345   1.01829   19.63048 1.000 95.99230  ? 1204 CLR A H221  1 
HETATM 5773 H  H222  . CLR E 3 .   ? 4.46347   1.10518   21.14981 1.000 95.99230  ? 1204 CLR A H222  1 
HETATM 5774 H  H231  . CLR E 3 .   ? 6.78301   1.83177   21.41148 1.000 99.36925  ? 1204 CLR A H231  1 
HETATM 5775 H  H232  . CLR E 3 .   ? 6.84045   1.96114   19.86779 1.000 99.36925  ? 1204 CLR A H232  1 
HETATM 5776 H  H241  . CLR E 3 .   ? 6.05602   3.87350   21.46653 1.000 99.90026  ? 1204 CLR A H241  1 
HETATM 5777 H  H242  . CLR E 3 .   ? 4.70184   3.33067   20.95137 1.000 99.90026  ? 1204 CLR A H242  1 
HETATM 5778 H  H25   . CLR E 3 .   ? 6.65970   4.65661   19.46315 1.000 103.30366 ? 1204 CLR A H25   1 
HETATM 5779 H  H261  . CLR E 3 .   ? 4.91609   5.98993   20.35090 1.000 114.39032 ? 1204 CLR A H261  1 
HETATM 5780 H  H262  . CLR E 3 .   ? 3.84535   5.10903   19.62880 1.000 114.39032 ? 1204 CLR A H262  1 
HETATM 5781 H  H263  . CLR E 3 .   ? 4.80450   6.01643   18.79182 1.000 114.39032 ? 1204 CLR A H263  1 
HETATM 5782 H  H271  . CLR E 3 .   ? 4.77757   2.96835   18.22159 1.000 99.10828  ? 1204 CLR A H271  1 
HETATM 5783 H  H272  . CLR E 3 .   ? 6.33362   2.95914   17.99664 1.000 99.10828  ? 1204 CLR A H272  1 
HETATM 5784 H  H273  . CLR E 3 .   ? 5.46468   4.14157   17.43202 1.000 99.10828  ? 1204 CLR A H273  1 
HETATM 5785 H  H1    . CLR E 3 .   ? 1.32066   -11.50732 20.34756 1.000 84.02822  ? 1204 CLR A H1    1 
HETATM 5786 C  C1    . OLA F 4 .   ? 36.02364  -15.96406 13.62407 1.000 97.99498  ? 1205 OLA A C1    1 
HETATM 5787 O  O1    . OLA F 4 .   ? 35.02117  -16.57981 13.20585 1.000 97.21664  ? 1205 OLA A O1    1 
HETATM 5788 O  O2    . OLA F 4 .   ? 36.98104  -16.45928 14.25779 1.000 103.21850 ? 1205 OLA A O2    1 
HETATM 5789 C  C2    . OLA F 4 .   ? 36.10297  -14.44754 13.34923 1.000 89.09162  ? 1205 OLA A C2    1 
HETATM 5790 C  C3    . OLA F 4 .   ? 36.68828  -13.60071 14.46800 1.000 87.42711  ? 1205 OLA A C3    1 
HETATM 5791 C  C4    . OLA F 4 .   ? 36.30831  -12.12928 14.36222 1.000 87.42948  ? 1205 OLA A C4    1 
HETATM 5792 C  C5    . OLA F 4 .   ? 37.33256  -11.31330 13.57849 1.000 83.43884  ? 1205 OLA A C5    1 
HETATM 5793 C  C6    . OLA F 4 .   ? 37.01760  -9.82350  13.51216 1.000 80.91395  ? 1205 OLA A C6    1 
HETATM 5794 C  C7    . OLA F 4 .   ? 36.31110  -9.35351  12.23949 1.000 83.02948  ? 1205 OLA A C7    1 
HETATM 5795 C  C8    . OLA F 4 .   ? 36.57751  -7.88113  11.94044 1.000 78.78592  ? 1205 OLA A C8    1 
HETATM 5796 C  C9    . OLA F 4 .   ? 35.32585  -7.08279  11.73793 1.000 73.43967  ? 1205 OLA A C9    1 
HETATM 5797 C  C10   . OLA F 4 .   ? 35.26681  -5.78896  11.43613 1.000 78.58215  ? 1205 OLA A C10   1 
HETATM 5798 C  C11   . OLA F 4 .   ? 36.44251  -4.89150  11.23561 1.000 73.06202  ? 1205 OLA A C11   1 
HETATM 5799 C  C12   . OLA F 4 .   ? 36.22022  -3.78314  10.20481 1.000 76.59072  ? 1205 OLA A C12   1 
HETATM 5800 C  C13   . OLA F 4 .   ? 37.51640  -3.08017  9.81835  1.000 78.40225  ? 1205 OLA A C13   1 
HETATM 5801 C  C14   . OLA F 4 .   ? 37.48627  -1.58720  10.12777 1.000 74.01285  ? 1205 OLA A C14   1 
HETATM 5802 C  C15   . OLA F 4 .   ? 36.84381  -0.72279  9.04520  1.000 74.41079  ? 1205 OLA A C15   1 
HETATM 5803 C  C16   . OLA F 4 .   ? 35.51718  -0.08974  9.44882  1.000 70.80018  ? 1205 OLA A C16   1 
HETATM 5804 C  C17   . OLA F 4 .   ? 35.18803  1.13579   8.60380  1.000 75.09957  ? 1205 OLA A C17   1 
HETATM 5805 C  C18   . OLA F 4 .   ? 35.48640  2.44055   9.32898  1.000 69.82911  ? 1205 OLA A C18   1 
HETATM 5806 H  H21   . OLA F 4 .   ? 35.21243  -14.12752 13.13610 1.000 106.95316 ? 1205 OLA A H21   1 
HETATM 5807 H  H22   . OLA F 4 .   ? 36.61744  -14.30929 12.53862 1.000 106.95316 ? 1205 OLA A H22   1 
HETATM 5808 H  H31   . OLA F 4 .   ? 36.39415  -13.94156 15.32719 1.000 104.95574 ? 1205 OLA A H31   1 
HETATM 5809 H  H32   . OLA F 4 .   ? 37.65521  -13.67771 14.46771 1.000 104.95574 ? 1205 OLA A H32   1 
HETATM 5810 H  H41   . OLA F 4 .   ? 35.43685  -12.05454 13.94286 1.000 104.95859 ? 1205 OLA A H41   1 
HETATM 5811 H  H42   . OLA F 4 .   ? 36.20667  -11.76150 15.25403 1.000 104.95859 ? 1205 OLA A H42   1 
HETATM 5812 H  H51   . OLA F 4 .   ? 38.21086  -11.43230 13.97262 1.000 100.16982 ? 1205 OLA A H51   1 
HETATM 5813 H  H52   . OLA F 4 .   ? 37.40085  -11.66129 12.67564 1.000 100.16982 ? 1205 OLA A H52   1 
HETATM 5814 H  H61   . OLA F 4 .   ? 36.47391  -9.59141  14.28120 1.000 97.13996  ? 1205 OLA A H61   1 
HETATM 5815 H  H62   . OLA F 4 .   ? 37.84677  -9.33081  13.61531 1.000 97.13996  ? 1205 OLA A H62   1 
HETATM 5816 H  H71   . OLA F 4 .   ? 36.59534  -9.89138  11.48397 1.000 99.67860  ? 1205 OLA A H71   1 
HETATM 5817 H  H72   . OLA F 4 .   ? 35.35507  -9.49759  12.31791 1.000 99.67860  ? 1205 OLA A H72   1 
HETATM 5818 H  H81   . OLA F 4 .   ? 37.14099  -7.82368  11.15298 1.000 94.58632  ? 1205 OLA A H81   1 
HETATM 5819 H  H82   . OLA F 4 .   ? 37.09715  -7.50774  12.66946 1.000 94.58632  ? 1205 OLA A H82   1 
HETATM 5820 H  H9    . OLA F 4 .   ? 34.52768  -7.54994  11.83592 1.000 88.17082  ? 1205 OLA A H9    1 
HETATM 5821 H  H10   . OLA F 4 .   ? 34.43129  -5.39258  11.33773 1.000 94.34180  ? 1205 OLA A H10   1 
HETATM 5822 H  H111  . OLA F 4 .   ? 36.67975  -4.49428  12.08816 1.000 87.71764  ? 1205 OLA A H111  1 
HETATM 5823 H  H112  . OLA F 4 .   ? 37.20347  -5.43050  10.96857 1.000 87.71764  ? 1205 OLA A H112  1 
HETATM 5824 H  H121  . OLA F 4 .   ? 35.80232  -4.15844  9.41399  1.000 91.95208  ? 1205 OLA A H121  1 
HETATM 5825 H  H122  . OLA F 4 .   ? 35.58942  -3.13670  10.55851 1.000 91.95208  ? 1205 OLA A H122  1 
HETATM 5826 H  H131  . OLA F 4 .   ? 38.25007  -3.50983  10.28526 1.000 94.12592  ? 1205 OLA A H131  1 
HETATM 5827 H  H132  . OLA F 4 .   ? 37.67666  -3.22877  8.87330  1.000 94.12592  ? 1205 OLA A H132  1 
HETATM 5828 H  H141  . OLA F 4 .   ? 38.39404  -1.28235  10.28244 1.000 88.85863  ? 1205 OLA A H141  1 
HETATM 5829 H  H142  . OLA F 4 .   ? 37.01585  -1.45165  10.96516 1.000 88.85863  ? 1205 OLA A H142  1 
HETATM 5830 H  H151  . OLA F 4 .   ? 36.70343  -1.25690  8.24775  1.000 89.33616  ? 1205 OLA A H151  1 
HETATM 5831 H  H152  . OLA F 4 .   ? 37.45903  -0.01819  8.78842  1.000 89.33616  ? 1205 OLA A H152  1 
HETATM 5832 H  H161  . OLA F 4 .   ? 34.80226  -0.74015  9.36666  1.000 85.00343  ? 1205 OLA A H161  1 
HETATM 5833 H  H162  . OLA F 4 .   ? 35.54231  0.16111   10.38549 1.000 85.00343  ? 1205 OLA A H162  1 
HETATM 5834 H  H171  . OLA F 4 .   ? 35.69181  1.10886   7.77532  1.000 90.16270  ? 1205 OLA A H171  1 
HETATM 5835 H  H172  . OLA F 4 .   ? 34.25191  1.11858   8.35026  1.000 90.16270  ? 1205 OLA A H172  1 
HETATM 5836 H  H181  . OLA F 4 .   ? 34.69139  2.80683   9.74696  1.000 83.83815  ? 1205 OLA A H181  1 
HETATM 5837 H  H182  . OLA F 4 .   ? 36.14807  2.31776   10.02756 1.000 83.83815  ? 1205 OLA A H182  1 
HETATM 5838 H  H183  . OLA F 4 .   ? 35.82979  3.11564   8.72297  1.000 83.83815  ? 1205 OLA A H183  1 
HETATM 5839 C  C1    . OLA G 4 .   ? 8.07205   -14.72768 8.23471  1.000 93.49212  ? 1206 OLA A C1    1 
HETATM 5840 O  O1    . OLA G 4 .   ? 8.33915   -15.71675 7.52230  1.000 99.39927  ? 1206 OLA A O1    1 
HETATM 5841 O  O2    . OLA G 4 .   ? 7.21636   -14.68011 9.14600  1.000 90.19543  ? 1206 OLA A O2    1 
HETATM 5842 C  C2    . OLA G 4 .   ? 8.86570   -13.43014 7.98354  1.000 85.44810  ? 1206 OLA A C2    1 
HETATM 5843 C  C3    . OLA G 4 .   ? 8.04855   -12.15666 7.84581  1.000 80.27800  ? 1206 OLA A C3    1 
HETATM 5844 C  C4    . OLA G 4 .   ? 8.77836   -11.07698 7.05736  1.000 82.42901  ? 1206 OLA A C4    1 
HETATM 5845 C  C5    . OLA G 4 .   ? 7.91515   -9.84846  6.77341  1.000 88.29295  ? 1206 OLA A C5    1 
HETATM 5846 C  C6    . OLA G 4 .   ? 8.24468   -8.64488  7.64964  1.000 89.36786  ? 1206 OLA A C6    1 
HETATM 5847 C  C7    . OLA G 4 .   ? 7.87868   -7.28845  7.05079  1.000 90.58038  ? 1206 OLA A C7    1 
HETATM 5848 C  C8    . OLA G 4 .   ? 9.09366   -6.41981  6.73070  1.000 92.95703  ? 1206 OLA A C8    1 
HETATM 5849 C  C9    . OLA G 4 .   ? 8.77938   -5.38325  5.69485  1.000 98.72450  ? 1206 OLA A C9    1 
HETATM 5850 C  C10   . OLA G 4 .   ? 9.60787   -4.86354  4.79042  1.000 103.19012 ? 1206 OLA A C10   1 
HETATM 5851 C  C11   . OLA G 4 .   ? 11.05583  -5.18122  4.59677  1.000 103.39117 ? 1206 OLA A C11   1 
HETATM 5852 C  C12   . OLA G 4 .   ? 11.76808  -4.20842  3.65078  1.000 108.45981 ? 1206 OLA A C12   1 
HETATM 5853 C  C13   . OLA G 4 .   ? 11.25669  -4.26079  2.21477  1.000 97.89538  ? 1206 OLA A C13   1 
HETATM 5854 H  H21   . OLA G 4 .   ? 9.50755   -13.32169 8.70268  1.000 102.58094 ? 1206 OLA A H21   1 
HETATM 5855 H  H22   . OLA G 4 .   ? 9.40418   -13.55206 7.18599  1.000 102.58094 ? 1206 OLA A H22   1 
HETATM 5856 H  H31   . OLA G 4 .   ? 7.82325   -11.81127 8.72379  1.000 96.37682  ? 1206 OLA A H31   1 
HETATM 5857 H  H32   . OLA G 4 .   ? 7.20346   -12.35094 7.41108  1.000 96.37682  ? 1206 OLA A H32   1 
HETATM 5858 H  H41   . OLA G 4 .   ? 9.57326   -10.81199 7.54606  1.000 98.95803  ? 1206 OLA A H41   1 
HETATM 5859 H  H42   . OLA G 4 .   ? 9.09374   -11.45505 6.22160  1.000 98.95803  ? 1206 OLA A H42   1 
HETATM 5860 H  H51   . OLA G 4 .   ? 8.00927   -9.59520  5.84179  1.000 105.99476 ? 1206 OLA A H51   1 
HETATM 5861 H  H52   . OLA G 4 .   ? 6.97956   -10.07643 6.89004  1.000 105.99476 ? 1206 OLA A H52   1 
HETATM 5862 H  H61   . OLA G 4 .   ? 7.79238   -8.75077  8.50118  1.000 107.28465 ? 1206 OLA A H61   1 
HETATM 5863 H  H62   . OLA G 4 .   ? 9.19367   -8.66023  7.84982  1.000 107.28465 ? 1206 OLA A H62   1 
HETATM 5864 H  H71   . OLA G 4 .   ? 7.29748   -6.80737  7.66044  1.000 108.73967 ? 1206 OLA A H71   1 
HETATM 5865 H  H72   . OLA G 4 .   ? 7.35955   -7.41705  6.24155  1.000 108.73967 ? 1206 OLA A H72   1 
HETATM 5866 H  H81   . OLA G 4 .   ? 9.81837   -6.99052  6.43075  1.000 111.59165 ? 1206 OLA A H81   1 
HETATM 5867 H  H82   . OLA G 4 .   ? 9.40428   -5.99964  7.54794  1.000 111.59165 ? 1206 OLA A H82   1 
HETATM 5868 H  H9    . OLA G 4 .   ? 7.90047   -5.07927  5.69831  1.000 118.51262 ? 1206 OLA A H9    1 
HETATM 5869 H  H10   . OLA G 4 .   ? 9.26424   -4.22898  4.20378  1.000 123.87135 ? 1206 OLA A H10   1 
HETATM 5870 H  H111  . OLA G 4 .   ? 11.13775  -6.08555  4.25564  1.000 124.11262 ? 1206 OLA A H111  1 
HETATM 5871 H  H112  . OLA G 4 .   ? 11.49796  -5.17798  5.46014  1.000 124.11262 ? 1206 OLA A H112  1 
HETATM 5872 H  H121  . OLA G 4 .   ? 12.71940  -4.39760  3.66109  1.000 130.19498 ? 1206 OLA A H121  1 
HETATM 5873 H  H122  . OLA G 4 .   ? 11.67176  -3.30645  3.99438  1.000 130.19498 ? 1206 OLA A H122  1 
HETATM 5874 H  H131  . OLA G 4 .   ? 11.16193  -5.19273  1.96224  1.000 117.51768 ? 1206 OLA A H131  1 
HETATM 5875 H  H132  . OLA G 4 .   ? 11.91283  -3.88439  1.60736  1.000 117.51768 ? 1206 OLA A H132  1 
HETATM 5876 C  C1    . OLA H 4 .   ? 20.69370  22.80057  28.12065 1.000 84.67112  ? 1207 OLA A C1    1 
HETATM 5877 O  O1    . OLA H 4 .   ? 20.86791  22.49329  26.92396 1.000 81.09124  ? 1207 OLA A O1    1 
HETATM 5878 O  O2    . OLA H 4 .   ? 20.95486  23.90562  28.64492 1.000 93.96323  ? 1207 OLA A O2    1 
HETATM 5879 C  C2    . OLA H 4 .   ? 20.10116  21.72079  29.04876 1.000 80.24990  ? 1207 OLA A C2    1 
HETATM 5880 C  C3    . OLA H 4 .   ? 20.57979  20.29774  28.80609 1.000 79.83442  ? 1207 OLA A C3    1 
HETATM 5881 C  C4    . OLA H 4 .   ? 19.78067  19.26243  29.58981 1.000 76.88503  ? 1207 OLA A C4    1 
HETATM 5882 C  C5    . OLA H 4 .   ? 20.42844  17.87889  29.59191 1.000 72.26099  ? 1207 OLA A C5    1 
HETATM 5883 C  C6    . OLA H 4 .   ? 19.45190  16.73613  29.33838 1.000 70.19710  ? 1207 OLA A C6    1 
HETATM 5884 C  C7    . OLA H 4 .   ? 20.08969  15.43985  28.84101 1.000 63.48086  ? 1207 OLA A C7    1 
HETATM 5885 H  H21   . OLA H 4 .   ? 19.13442  21.75109  28.97537 1.000 96.34309  ? 1207 OLA A H21   1 
HETATM 5886 H  H22   . OLA H 4 .   ? 20.28870  21.97018  29.96720 1.000 96.34309  ? 1207 OLA A H22   1 
HETATM 5887 H  H31   . OLA H 4 .   ? 20.52655  20.08863  27.86039 1.000 95.84452  ? 1207 OLA A H31   1 
HETATM 5888 H  H32   . OLA H 4 .   ? 21.51699  20.21995  29.04377 1.000 95.84452  ? 1207 OLA A H32   1 
HETATM 5889 H  H41   . OLA H 4 .   ? 19.66930  19.57309  30.50194 1.000 92.30525  ? 1207 OLA A H41   1 
HETATM 5890 H  H42   . OLA H 4 .   ? 18.88681  19.20478  29.21753 1.000 92.30525  ? 1207 OLA A H42   1 
HETATM 5891 H  H51   . OLA H 4 .   ? 21.12888  17.84893  28.92155 1.000 86.75641  ? 1207 OLA A H51   1 
HETATM 5892 H  H52   . OLA H 4 .   ? 20.87215  17.73104  30.44171 1.000 86.75641  ? 1207 OLA A H52   1 
HETATM 5893 H  H61   . OLA H 4 .   ? 18.96499  16.55896  30.15840 1.000 84.27974  ? 1207 OLA A H61   1 
HETATM 5894 H  H62   . OLA H 4 .   ? 18.78920  17.03372  28.69560 1.000 84.27974  ? 1207 OLA A H62   1 
HETATM 5895 H  H71   . OLA H 4 .   ? 20.87614  15.22445  29.36710 1.000 76.22025  ? 1207 OLA A H71   1 
HETATM 5896 H  H72   . OLA H 4 .   ? 19.47084  14.70619  28.98057 1.000 76.22025  ? 1207 OLA A H72   1 
HETATM 5897 C  C1    . OLA I 4 .   ? 25.18941  -14.21602 7.87995  1.000 89.23493  ? 1208 OLA A C1    1 
HETATM 5898 O  O1    . OLA I 4 .   ? 26.26446  -13.58758 7.98159  1.000 83.56557  ? 1208 OLA A O1    1 
HETATM 5899 O  O2    . OLA I 4 .   ? 24.65626  -14.90770 8.77454  1.000 91.50013  ? 1208 OLA A O2    1 
HETATM 5900 C  C2    . OLA I 4 .   ? 24.43469  -14.14139 6.53430  1.000 88.61002  ? 1208 OLA A C2    1 
HETATM 5901 C  C3    . OLA I 4 .   ? 23.79196  -12.79729 6.21908  1.000 85.60590  ? 1208 OLA A C3    1 
HETATM 5902 C  C4    . OLA I 4 .   ? 22.48088  -12.89019 5.44380  1.000 90.85021  ? 1208 OLA A C4    1 
HETATM 5903 C  C5    . OLA I 4 .   ? 22.36658  -11.89948 4.28155  1.000 91.30807  ? 1208 OLA A C5    1 
HETATM 5904 C  C6    . OLA I 4 .   ? 21.52995  -10.65876 4.58778  1.000 88.50561  ? 1208 OLA A C6    1 
HETATM 5905 C  C7    . OLA I 4 .   ? 21.93232  -9.39978  3.82161  1.000 82.44312  ? 1208 OLA A C7    1 
HETATM 5906 C  C8    . OLA I 4 .   ? 21.00988  -8.20084  4.04739  1.000 82.35982  ? 1208 OLA A C8    1 
HETATM 5907 C  C9    . OLA I 4 .   ? 21.74799  -7.05518  4.67525  1.000 72.76652  ? 1208 OLA A C9    1 
HETATM 5908 C  C10   . OLA I 4 .   ? 21.90070  -5.81362  4.21420  1.000 73.44846  ? 1208 OLA A C10   1 
HETATM 5909 C  C11   . OLA I 4 .   ? 21.37621  -5.21413  2.94799  1.000 76.05520  ? 1208 OLA A C11   1 
HETATM 5910 C  C12   . OLA I 4 .   ? 20.74183  -3.83080  3.15601  1.000 75.65840  ? 1208 OLA A C12   1 
HETATM 5911 C  C13   . OLA I 4 .   ? 20.55970  -3.03577  1.86784  1.000 82.04875  ? 1208 OLA A C13   1 
HETATM 5912 C  C14   . OLA I 4 .   ? 20.17648  -1.58074  2.12641  1.000 73.86599  ? 1208 OLA A C14   1 
HETATM 5913 C  C15   . OLA I 4 .   ? 21.27105  -0.70937  2.74435  1.000 84.96736  ? 1208 OLA A C15   1 
HETATM 5914 C  C16   . OLA I 4 .   ? 20.76738  0.61414   3.31511  1.000 82.11683  ? 1208 OLA A C16   1 
HETATM 5915 H  H21   . OLA I 4 .   ? 25.04846  -14.38111 5.82246  1.000 106.37524 ? 1208 OLA A H21   1 
HETATM 5916 H  H22   . OLA I 4 .   ? 23.75655  -14.83485 6.52188  1.000 106.37524 ? 1208 OLA A H22   1 
HETATM 5917 H  H31   . OLA I 4 .   ? 24.41361  -12.25298 5.71097  1.000 102.77029 ? 1208 OLA A H31   1 
HETATM 5918 H  H32   . OLA I 4 .   ? 23.62921  -12.31522 7.04493  1.000 102.77029 ? 1208 OLA A H32   1 
HETATM 5919 H  H41   . OLA I 4 .   ? 21.74425  -12.75200 6.05958  1.000 109.06347 ? 1208 OLA A H41   1 
HETATM 5920 H  H42   . OLA I 4 .   ? 22.38075  -13.79474 5.10815  1.000 109.06347 ? 1208 OLA A H42   1 
HETATM 5921 H  H51   . OLA I 4 .   ? 23.25451  -11.61879 4.01007  1.000 109.61290 ? 1208 OLA A H51   1 
HETATM 5922 H  H52   . OLA I 4 .   ? 21.98699  -12.35035 3.51114  1.000 109.61290 ? 1208 OLA A H52   1 
HETATM 5923 H  H61   . OLA I 4 .   ? 20.59958  -10.86151 4.40286  1.000 106.24995 ? 1208 OLA A H61   1 
HETATM 5924 H  H62   . OLA I 4 .   ? 21.57852  -10.48215 5.54033  1.000 106.24995 ? 1208 OLA A H62   1 
HETATM 5925 H  H71   . OLA I 4 .   ? 21.96298  -9.59526  2.87201  1.000 98.97496  ? 1208 OLA A H71   1 
HETATM 5926 H  H72   . OLA I 4 .   ? 22.83664  -9.14792  4.06591  1.000 98.97496  ? 1208 OLA A H72   1 
HETATM 5927 H  H81   . OLA I 4 .   ? 20.26559  -8.47441  4.60603  1.000 98.87499  ? 1208 OLA A H81   1 
HETATM 5928 H  H82   . OLA I 4 .   ? 20.62373  -7.93382  3.19858  1.000 98.87499  ? 1208 OLA A H82   1 
HETATM 5929 H  H9    . OLA I 4 .   ? 22.14453  -7.25525  5.49234  1.000 87.36304  ? 1208 OLA A H9    1 
HETATM 5930 H  H10   . OLA I 4 .   ? 22.39754  -5.22632  4.73682  1.000 88.18136  ? 1208 OLA A H10   1 
HETATM 5931 H  H111  . OLA I 4 .   ? 20.72395  -5.81717  2.55837  1.000 91.30946  ? 1208 OLA A H111  1 
HETATM 5932 H  H112  . OLA I 4 .   ? 22.09970  -5.14820  2.30524  1.000 91.30946  ? 1208 OLA A H112  1 
HETATM 5933 H  H121  . OLA I 4 .   ? 21.29015  -3.32197  3.77354  1.000 90.83329  ? 1208 OLA A H121  1 
HETATM 5934 H  H122  . OLA I 4 .   ? 19.88179  -3.94038  3.59100  1.000 90.83329  ? 1208 OLA A H122  1 
HETATM 5935 H  H131  . OLA I 4 .   ? 19.88347  -3.47509  1.32875  1.000 98.50172  ? 1208 OLA A H131  1 
HETATM 5936 H  H132  . OLA I 4 .   ? 21.38301  -3.08523  1.35734  1.000 98.50172  ? 1208 OLA A H132  1 
HETATM 5937 H  H141  . OLA I 4 .   ? 19.89226  -1.18327  1.28847  1.000 88.68240  ? 1208 OLA A H141  1 
HETATM 5938 H  H142  . OLA I 4 .   ? 19.39724  -1.56517  2.70385  1.000 88.68240  ? 1208 OLA A H142  1 
HETATM 5939 H  H151  . OLA I 4 .   ? 21.71800  -1.20338  3.44939  1.000 102.00405 ? 1208 OLA A H151  1 
HETATM 5940 H  H152  . OLA I 4 .   ? 21.95087  -0.52331  2.07792  1.000 102.00405 ? 1208 OLA A H152  1 
HETATM 5941 H  H161  . OLA I 4 .   ? 20.24235  1.07696   2.64419  1.000 98.58341  ? 1208 OLA A H161  1 
HETATM 5942 H  H162  . OLA I 4 .   ? 20.16618  0.44712   4.05771  1.000 98.58341  ? 1208 OLA A H162  1 
HETATM 5943 C  C1    . OLA J 4 .   ? 36.11218  15.24056  4.96325  0.754 81.67616  ? 1209 OLA A C1    1 
HETATM 5944 O  O1    . OLA J 4 .   ? 36.07337  14.09272  5.45223  0.754 76.63022  ? 1209 OLA A O1    1 
HETATM 5945 O  O2    . OLA J 4 .   ? 36.47109  16.28145  5.55612  0.754 84.63736  ? 1209 OLA A O2    1 
HETATM 5946 C  C2    . OLA J 4 .   ? 35.67701  15.40665  3.49198  0.754 80.93944  ? 1209 OLA A C2    1 
HETATM 5947 C  C3    . OLA J 4 .   ? 34.45643  14.60882  3.05799  0.754 78.31092  ? 1209 OLA A C3    1 
HETATM 5948 C  C4    . OLA J 4 .   ? 33.63786  15.31623  1.98371  0.754 83.94792  ? 1209 OLA A C4    1 
HETATM 5949 C  C5    . OLA J 4 .   ? 32.53818  14.43942  1.38558  0.754 80.89991  ? 1209 OLA A C5    1 
HETATM 5950 C  C6    . OLA J 4 .   ? 31.22903  14.45822  2.16704  0.754 74.85117  ? 1209 OLA A C6    1 
HETATM 5951 C  C7    . OLA J 4 .   ? 30.78072  13.10283  2.71229  0.754 72.14831  ? 1209 OLA A C7    1 
HETATM 5952 C  C8    . OLA J 4 .   ? 29.29524  13.04567  3.06038  0.754 76.57608  ? 1209 OLA A C8    1 
HETATM 5953 C  C9    . OLA J 4 .   ? 28.83964  11.63313  3.26500  0.754 62.63331  ? 1209 OLA A C9    1 
HETATM 5954 C  C10   . OLA J 4 .   ? 27.77060  11.21082  3.93527  0.754 60.08073  ? 1209 OLA A C10   1 
HETATM 5955 H  H21   . OLA J 4 .   ? 36.42855  15.17608  2.92372  0.754 97.17055  ? 1209 OLA A H21   1 
HETATM 5956 H  H22   . OLA J 4 .   ? 35.51911  16.34905  3.32513  0.754 97.17055  ? 1209 OLA A H22   1 
HETATM 5957 H  H31   . OLA J 4 .   ? 33.88799  14.43286  3.82403  0.754 94.01632  ? 1209 OLA A H31   1 
HETATM 5958 H  H32   . OLA J 4 .   ? 34.73145  13.74019  2.72522  0.754 94.01632  ? 1209 OLA A H32   1 
HETATM 5959 H  H41   . OLA J 4 .   ? 34.23383  15.61800  1.28039  0.754 100.78072 ? 1209 OLA A H41   1 
HETATM 5960 H  H42   . OLA J 4 .   ? 33.24604  16.11857  2.36268  0.754 100.78072 ? 1209 OLA A H42   1 
HETATM 5961 H  H51   . OLA J 4 .   ? 32.36328  14.71906  0.47338  0.754 97.12310  ? 1209 OLA A H51   1 
HETATM 5962 H  H52   . OLA J 4 .   ? 32.85357  13.52423  1.32350  0.754 97.12310  ? 1209 OLA A H52   1 
HETATM 5963 H  H61   . OLA J 4 .   ? 31.31802  15.08483  2.90212  0.754 89.86462  ? 1209 OLA A H61   1 
HETATM 5964 H  H62   . OLA J 4 .   ? 30.53367  14.81824  1.59453  0.754 89.86462  ? 1209 OLA A H62   1 
HETATM 5965 H  H71   . OLA J 4 .   ? 31.29861  12.88089  3.50187  0.754 86.62118  ? 1209 OLA A H71   1 
HETATM 5966 H  H72   . OLA J 4 .   ? 30.98014  12.40828  2.06520  0.754 86.62118  ? 1209 OLA A H72   1 
HETATM 5967 H  H81   . OLA J 4 .   ? 29.13556  13.57492  3.85744  0.754 91.93452  ? 1209 OLA A H81   1 
HETATM 5968 H  H82   . OLA J 4 .   ? 28.78669  13.46926  2.35127  0.754 91.93452  ? 1209 OLA A H82   1 
HETATM 5969 H  H9    . OLA J 4 .   ? 29.38013  10.98779  2.86965  0.754 75.20319  ? 1209 OLA A H9    1 
HETATM 5970 H  H10   . OLA J 4 .   ? 27.62035  10.29390  3.96816  0.754 72.14009  ? 1209 OLA A H10   1 
HETATM 5971 C  C1    . OLA K 4 .   ? 17.94156  12.91179  3.77976  1.000 91.84125  ? 1210 OLA A C1    1 
HETATM 5972 C  C2    . OLA K 4 .   ? 17.77617  11.49102  4.35810  1.000 96.20663  ? 1210 OLA A C2    1 
HETATM 5973 C  C3    . OLA K 4 .   ? 16.43896  11.17160  5.00963  1.000 100.91423 ? 1210 OLA A C3    1 
HETATM 5974 C  C4    . OLA K 4 .   ? 15.92684  9.77012   4.69115  1.000 90.04369  ? 1210 OLA A C4    1 
HETATM 5975 C  C5    . OLA K 4 .   ? 16.92048  8.65360   5.01932  1.000 103.23842 ? 1210 OLA A C5    1 
HETATM 5976 C  C6    . OLA K 4 .   ? 16.33889  7.55277   5.90170  1.000 86.53650  ? 1210 OLA A C6    1 
HETATM 5977 C  C7    . OLA K 4 .   ? 17.17510  6.27698   5.98239  1.000 75.32227  ? 1210 OLA A C7    1 
HETATM 5978 H  H21   . OLA K 4 .   ? 18.48718  11.34055  5.00053  1.000 115.49118 ? 1210 OLA A H21   1 
HETATM 5979 H  H22   . OLA K 4 .   ? 17.94429  10.85286  3.64720  1.000 115.49118 ? 1210 OLA A H22   1 
HETATM 5980 H  H31   . OLA K 4 .   ? 15.77453  11.81966  4.72778  1.000 121.14030 ? 1210 OLA A H31   1 
HETATM 5981 H  H32   . OLA K 4 .   ? 16.51278  11.26713  5.97209  1.000 121.14030 ? 1210 OLA A H32   1 
HETATM 5982 H  H41   . OLA K 4 .   ? 15.10072  9.62143   5.17727  1.000 108.09564 ? 1210 OLA A H41   1 
HETATM 5983 H  H42   . OLA K 4 .   ? 15.69299  9.72920   3.75065  1.000 108.09564 ? 1210 OLA A H42   1 
HETATM 5984 H  H51   . OLA K 4 .   ? 17.69938  9.03101   5.45724  1.000 123.92932 ? 1210 OLA A H51   1 
HETATM 5985 H  H52   . OLA K 4 .   ? 17.24800  8.25864   4.19613  1.000 123.92932 ? 1210 OLA A H52   1 
HETATM 5986 H  H61   . OLA K 4 .   ? 16.21245  7.90887   6.79507  1.000 103.88701 ? 1210 OLA A H61   1 
HETATM 5987 H  H62   . OLA K 4 .   ? 15.45201  7.33333   5.57582  1.000 103.88701 ? 1210 OLA A H62   1 
HETATM 5988 H  H71   . OLA K 4 .   ? 17.09265  5.87556   6.86151  1.000 90.42994  ? 1210 OLA A H71   1 
HETATM 5989 H  H72   . OLA K 4 .   ? 18.11301  6.50622   5.88643  1.000 90.42994  ? 1210 OLA A H72   1 
HETATM 5990 C  C1    . OLA L 4 .   ? 44.06961  24.82905  12.81991 1.000 108.35390 ? 1211 OLA A C1    1 
HETATM 5991 O  O1    . OLA L 4 .   ? 44.94164  25.46931  12.19745 1.000 110.37970 ? 1211 OLA A O1    1 
HETATM 5992 O  O2    . OLA L 4 .   ? 43.15711  25.31556  13.52346 1.000 105.58447 ? 1211 OLA A O2    1 
HETATM 5993 C  C2    . OLA L 4 .   ? 44.09795  23.28942  12.73080 1.000 113.20751 ? 1211 OLA A C2    1 
HETATM 5994 C  C3    . OLA L 4 .   ? 43.39293  22.55447  13.85854 1.000 106.19010 ? 1211 OLA A C3    1 
HETATM 5995 C  C4    . OLA L 4 .   ? 43.61306  21.04787  13.83212 1.000 105.69795 ? 1211 OLA A C4    1 
HETATM 5996 C  C5    . OLA L 4 .   ? 42.87832  20.33516  14.96598 1.000 104.12563 ? 1211 OLA A C5    1 
HETATM 5997 C  C6    . OLA L 4 .   ? 41.40819  20.04873  14.67126 1.000 98.83804  ? 1211 OLA A C6    1 
HETATM 5998 C  C7    . OLA L 4 .   ? 40.54045  19.80006  15.90723 1.000 106.14429 ? 1211 OLA A C7    1 
HETATM 5999 C  C8    . OLA L 4 .   ? 39.59081  18.60874  15.78662 1.000 105.42839 ? 1211 OLA A C8    1 
HETATM 6000 C  C9    . OLA L 4 .   ? 38.30348  18.99176  15.12156 1.000 97.32469  ? 1211 OLA A C9    1 
HETATM 6001 C  C10   . OLA L 4 .   ? 37.65889  18.34143  14.15451 1.000 94.13600  ? 1211 OLA A C10   1 
HETATM 6002 C  C11   . OLA L 4 .   ? 38.04634  17.06422  13.47983 1.000 87.12745  ? 1211 OLA A C11   1 
HETATM 6003 C  C12   . OLA L 4 .   ? 37.44308  15.81632  14.13686 1.000 88.47360  ? 1211 OLA A C12   1 
HETATM 6004 C  C13   . OLA L 4 .   ? 37.86292  14.51735  13.46093 1.000 86.59518  ? 1211 OLA A C13   1 
HETATM 6005 C  C14   . OLA L 4 .   ? 37.80407  13.31617  14.40024 1.000 86.61755  ? 1211 OLA A C14   1 
HETATM 6006 C  C15   . OLA L 4 .   ? 38.65260  12.11764  13.97129 1.000 88.34246  ? 1211 OLA A C15   1 
HETATM 6007 C  C16   . OLA L 4 .   ? 38.24991  10.79811  14.62315 1.000 91.00699  ? 1211 OLA A C16   1 
HETATM 6008 C  C17   . OLA L 4 .   ? 38.47499  9.58659   13.72560 1.000 87.60806  ? 1211 OLA A C17   1 
HETATM 6009 H  H21   . OLA L 4 .   ? 43.71267  23.02289  11.88144 1.000 135.89223 ? 1211 OLA A H21   1 
HETATM 6010 H  H22   . OLA L 4 .   ? 45.02281  23.00045  12.68586 1.000 135.89223 ? 1211 OLA A H22   1 
HETATM 6011 H  H31   . OLA L 4 .   ? 43.69431  22.90030  14.71322 1.000 127.47134 ? 1211 OLA A H31   1 
HETATM 6012 H  H32   . OLA L 4 .   ? 42.44023  22.73274  13.82002 1.000 127.47134 ? 1211 OLA A H32   1 
HETATM 6013 H  H41   . OLA L 4 .   ? 44.56363  20.86222  13.88551 1.000 126.88076 ? 1211 OLA A H41   1 
HETATM 6014 H  H42   . OLA L 4 .   ? 43.32119  20.69663  12.97635 1.000 126.88076 ? 1211 OLA A H42   1 
HETATM 6015 H  H51   . OLA L 4 .   ? 43.32758  19.49930  15.16700 1.000 124.99397 ? 1211 OLA A H51   1 
HETATM 6016 H  H52   . OLA L 4 .   ? 42.93925  20.86688  15.77497 1.000 124.99397 ? 1211 OLA A H52   1 
HETATM 6017 H  H61   . OLA L 4 .   ? 41.04320  20.79335  14.16804 1.000 118.64887 ? 1211 OLA A H61   1 
HETATM 6018 H  H62   . OLA L 4 .   ? 41.35526  19.27961  14.08257 1.000 118.64887 ? 1211 OLA A H62   1 
HETATM 6019 H  H71   . OLA L 4 .   ? 41.11084  19.66648  16.68036 1.000 127.41636 ? 1211 OLA A H71   1 
HETATM 6020 H  H72   . OLA L 4 .   ? 40.01954  20.59504  16.10102 1.000 127.41636 ? 1211 OLA A H72   1 
HETATM 6021 H  H81   . OLA L 4 .   ? 39.42224  18.24909  16.67157 1.000 126.55728 ? 1211 OLA A H81   1 
HETATM 6022 H  H82   . OLA L 4 .   ? 40.03274  17.90230  15.29010 1.000 126.55728 ? 1211 OLA A H82   1 
HETATM 6023 H  H9    . OLA L 4 .   ? 37.92321  19.78085  15.43405 1.000 116.83284 ? 1211 OLA A H9    1 
HETATM 6024 H  H10   . OLA L 4 .   ? 36.86435  18.71389  13.84647 1.000 113.00642 ? 1211 OLA A H10   1 
HETATM 6025 H  H111  . OLA L 4 .   ? 39.01365  16.99231  13.47438 1.000 104.59616 ? 1211 OLA A H111  1 
HETATM 6026 H  H112  . OLA L 4 .   ? 37.77404  17.10471  12.54971 1.000 104.59616 ? 1211 OLA A H112  1 
HETATM 6027 H  H121  . OLA L 4 .   ? 36.47581  15.88855  14.12819 1.000 106.21154 ? 1211 OLA A H121  1 
HETATM 6028 H  H122  . OLA L 4 .   ? 37.70046  15.79336  15.07181 1.000 106.21154 ? 1211 OLA A H122  1 
HETATM 6029 H  H131  . OLA L 4 .   ? 38.76036  14.63067  13.11070 1.000 103.95744 ? 1211 OLA A H131  1 
HETATM 6030 H  H132  . OLA L 4 .   ? 37.29090  14.37425  12.69073 1.000 103.95744 ? 1211 OLA A H132  1 
HETATM 6031 H  H141  . OLA L 4 .   ? 36.87969  13.03587  14.48875 1.000 103.98428 ? 1211 OLA A H141  1 
HETATM 6032 H  H142  . OLA L 4 .   ? 38.07985  13.60031  15.28574 1.000 103.98428 ? 1211 OLA A H142  1 
HETATM 6033 H  H151  . OLA L 4 .   ? 39.58481  12.29332  14.17384 1.000 106.05417 ? 1211 OLA A H151  1 
HETATM 6034 H  H152  . OLA L 4 .   ? 38.60433  12.01649  13.00778 1.000 106.05417 ? 1211 OLA A H152  1 
HETATM 6035 H  H161  . OLA L 4 .   ? 37.31482  10.83417  14.87854 1.000 109.25160 ? 1211 OLA A H161  1 
HETATM 6036 H  H162  . OLA L 4 .   ? 38.74650  10.67845  15.44776 1.000 109.25160 ? 1211 OLA A H162  1 
HETATM 6037 H  H171  . OLA L 4 .   ? 38.05063  9.72822   12.86474 1.000 105.17289 ? 1211 OLA A H171  1 
HETATM 6038 H  H172  . OLA L 4 .   ? 39.42442  9.49927   13.54616 1.000 105.17289 ? 1211 OLA A H172  1 
HETATM 6039 C  C9    . OLA M 4 .   ? 7.80893   16.52569  16.70119 1.000 71.79987  ? 1212 OLA A C9    1 
HETATM 6040 C  C10   . OLA M 4 .   ? 8.73587   15.58106  16.54129 1.000 73.80969  ? 1212 OLA A C10   1 
HETATM 6041 C  C11   . OLA M 4 .   ? 9.91132   15.28497  17.42123 1.000 66.27766  ? 1212 OLA A C11   1 
HETATM 6042 C  C12   . OLA M 4 .   ? 10.53730  13.91346  17.15426 1.000 66.81273  ? 1212 OLA A C12   1 
HETATM 6043 C  C13   . OLA M 4 .   ? 10.45389  12.95319  18.33626 1.000 67.35516  ? 1212 OLA A C13   1 
HETATM 6044 C  C14   . OLA M 4 .   ? 9.96685   11.57241  17.91053 1.000 64.12328  ? 1212 OLA A C14   1 
HETATM 6045 C  C15   . OLA M 4 .   ? 9.09776   10.84529  18.93427 1.000 65.72349  ? 1212 OLA A C15   1 
HETATM 6046 C  C16   . OLA M 4 .   ? 8.76645   9.40369   18.55271 1.000 68.42499  ? 1212 OLA A C16   1 
HETATM 6047 C  C17   . OLA M 4 .   ? 7.86015   8.70673   19.55910 1.000 79.38515  ? 1212 OLA A C17   1 
HETATM 6048 C  C18   . OLA M 4 .   ? 8.02172   7.19358   19.54268 1.000 84.02562  ? 1212 OLA A C18   1 
HETATM 6049 C  C3    . OLA N 4 .   ? 34.01046  -10.69008 2.99791  1.000 74.91791  ? 1213 OLA A C3    1 
HETATM 6050 C  C4    . OLA N 4 .   ? 33.50837  -9.26333  2.80622  1.000 81.08349  ? 1213 OLA A C4    1 
HETATM 6051 C  C5    . OLA N 4 .   ? 34.12952  -8.56898  1.59431  1.000 77.23493  ? 1213 OLA A C5    1 
HETATM 6052 C  C6    . OLA N 4 .   ? 33.95558  -7.05384  1.58729  1.000 74.10072  ? 1213 OLA A C6    1 
HETATM 6053 C  C7    . OLA N 4 .   ? 34.85324  -6.31277  0.59980  1.000 86.84159  ? 1213 OLA A C7    1 
HETATM 6054 C  C8    . OLA N 4 .   ? 35.23751  -4.90279  1.04207  1.000 83.40214  ? 1213 OLA A C8    1 
HETATM 6055 C  C9    . OLA N 4 .   ? 34.09455  -3.94591  0.87348  1.000 73.14619  ? 1213 OLA A C9    1 
HETATM 6056 H  H31   . OLA N 4 .   ? 34.88322  -10.66091 3.42126  1.000 89.94470  ? 1213 OLA A H31   1 
HETATM 6057 H  H32   . OLA N 4 .   ? 34.15051  -11.10037 2.13091  1.000 89.94470  ? 1213 OLA A H32   1 
HETATM 6058 H  H41   . OLA N 4 .   ? 33.69461  -8.75126  3.60872  1.000 97.34340  ? 1213 OLA A H41   1 
HETATM 6059 H  H42   . OLA N 4 .   ? 32.54254  -9.27645  2.71734  1.000 97.34340  ? 1213 OLA A H42   1 
HETATM 6060 H  H51   . OLA N 4 .   ? 33.74535  -8.93324  0.78152  1.000 92.72513  ? 1213 OLA A H51   1 
HETATM 6061 H  H52   . OLA N 4 .   ? 35.07608  -8.77690  1.55315  1.000 92.72513  ? 1213 OLA A H52   1 
HETATM 6062 H  H61   . OLA N 4 .   ? 34.11882  -6.71930  2.48302  1.000 88.96409  ? 1213 OLA A H61   1 
HETATM 6063 H  H62   . OLA N 4 .   ? 33.02742  -6.84964  1.39310  1.000 88.96409  ? 1213 OLA A H62   1 
HETATM 6064 H  H71   . OLA N 4 .   ? 34.41298  -6.26117  -0.26300 1.000 104.25313 ? 1213 OLA A H71   1 
HETATM 6065 H  H72   . OLA N 4 .   ? 35.66293  -6.82541  0.44979  1.000 104.25313 ? 1213 OLA A H72   1 
HETATM 6066 H  H81   . OLA N 4 .   ? 35.52653  -4.92904  1.96764  1.000 100.12579 ? 1213 OLA A H81   1 
HETATM 6067 H  H82   . OLA N 4 .   ? 36.00675  -4.60881  0.52948  1.000 100.12579 ? 1213 OLA A H82   1 
HETATM 6068 H  H9    . OLA N 4 .   ? 33.49176  -3.92083  1.58061  1.000 87.81865  ? 1213 OLA A H9    1 
HETATM 6069 C  C1    . OLA O 4 .   ? 32.44938  -7.52499  36.49691 1.000 76.98584  ? 1214 OLA A C1    1 
HETATM 6070 O  O1    . OLA O 4 .   ? 33.54046  -7.64040  35.90329 1.000 89.25523  ? 1214 OLA A O1    1 
HETATM 6071 O  O2    . OLA O 4 .   ? 31.73341  -8.46450  36.90986 1.000 79.31050  ? 1214 OLA A O2    1 
HETATM 6072 C  C2    . OLA O 4 .   ? 31.91775  -6.09879  36.75640 1.000 77.77734  ? 1214 OLA A C2    1 
HETATM 6073 C  C3    . OLA O 4 .   ? 32.95298  -5.03147  37.08249 1.000 74.09508  ? 1214 OLA A C3    1 
HETATM 6074 C  C4    . OLA O 4 .   ? 32.45623  -3.62288  36.77776 1.000 74.99863  ? 1214 OLA A C4    1 
HETATM 6075 C  C5    . OLA O 4 .   ? 32.49604  -2.65094  37.95949 1.000 76.48514  ? 1214 OLA A C5    1 
HETATM 6076 C  C6    . OLA O 4 .   ? 31.38332  -1.60898  37.88465 1.000 73.77166  ? 1214 OLA A C6    1 
HETATM 6077 C  C7    . OLA O 4 .   ? 31.64062  -0.25311  38.53860 1.000 72.52477  ? 1214 OLA A C7    1 
HETATM 6078 C  C8    . OLA O 4 .   ? 30.54710  0.75191   38.18014 1.000 76.15875  ? 1214 OLA A C8    1 
HETATM 6079 C  C9    . OLA O 4 .   ? 30.62129  2.01771   38.98016 1.000 75.43336  ? 1214 OLA A C9    1 
HETATM 6080 C  C10   . OLA O 4 .   ? 30.55807  3.27157   38.53101 1.000 88.03382  ? 1214 OLA A C10   1 
HETATM 6081 C  C11   . OLA O 4 .   ? 30.40623  3.74967   37.12153 1.000 87.61108  ? 1214 OLA A C11   1 
HETATM 6082 C  C12   . OLA O 4 .   ? 29.05412  4.41633   36.83579 1.000 85.56865  ? 1214 OLA A C12   1 
HETATM 6083 C  C13   . OLA O 4 .   ? 28.89525  5.79600   37.46711 1.000 80.54432  ? 1214 OLA A C13   1 
HETATM 6084 C  C14   . OLA O 4 .   ? 27.72658  6.57716   36.86921 1.000 79.33113  ? 1214 OLA A C14   1 
HETATM 6085 C  C15   . OLA O 4 .   ? 26.44347  6.57346   37.70057 1.000 80.83488  ? 1214 OLA A C15   1 
HETATM 6086 H  H21   . OLA O 4 .   ? 31.26973  -6.14366  37.47678 1.000 93.37602  ? 1214 OLA A H21   1 
HETATM 6087 H  H22   . OLA O 4 .   ? 31.40749  -5.81998  35.98001 1.000 93.37602  ? 1214 OLA A H22   1 
HETATM 6088 H  H31   . OLA O 4 .   ? 33.20035  -5.08534  38.01887 1.000 88.95731  ? 1214 OLA A H31   1 
HETATM 6089 H  H32   . OLA O 4 .   ? 33.76733  -5.19625  36.58192 1.000 88.95731  ? 1214 OLA A H32   1 
HETATM 6090 H  H41   . OLA O 4 .   ? 31.54751  -3.68250  36.44374 1.000 90.04157  ? 1214 OLA A H41   1 
HETATM 6091 H  H42   . OLA O 4 .   ? 32.98427  -3.26124  36.04886 1.000 90.04157  ? 1214 OLA A H42   1 
HETATM 6092 H  H51   . OLA O 4 .   ? 33.35604  -2.20340  37.99125 1.000 91.82539  ? 1214 OLA A H51   1 
HETATM 6093 H  H52   . OLA O 4 .   ? 32.42429  -3.14080  38.79363 1.000 91.82539  ? 1214 OLA A H52   1 
HETATM 6094 H  H61   . OLA O 4 .   ? 31.17281  -1.46594  36.94864 1.000 88.56921  ? 1214 OLA A H61   1 
HETATM 6095 H  H62   . OLA O 4 .   ? 30.58649  -1.99650  38.27936 1.000 88.56921  ? 1214 OLA A H62   1 
HETATM 6096 H  H71   . OLA O 4 .   ? 32.50409  0.09369   38.26467 1.000 87.07294  ? 1214 OLA A H71   1 
HETATM 6097 H  H72   . OLA O 4 .   ? 31.69137  -0.34910  39.50251 1.000 87.07294  ? 1214 OLA A H72   1 
HETATM 6098 H  H81   . OLA O 4 .   ? 29.68441  0.32700   38.30713 1.000 91.43372  ? 1214 OLA A H81   1 
HETATM 6099 H  H82   . OLA O 4 .   ? 30.61052  0.95157   37.23304 1.000 91.43372  ? 1214 OLA A H82   1 
HETATM 6100 H  H9    . OLA O 4 .   ? 30.72351  1.89503   39.89634 1.000 90.56324  ? 1214 OLA A H9    1 
HETATM 6101 H  H10   . OLA O 4 .   ? 30.61403  3.95214   39.16236 1.000 105.68380 ? 1214 OLA A H10   1 
HETATM 6102 H  H111  . OLA O 4 .   ? 30.52945  2.99816   36.52073 1.000 105.17651 ? 1214 OLA A H111  1 
HETATM 6103 H  H112  . OLA O 4 .   ? 31.12234  4.37320   36.92327 1.000 105.17651 ? 1214 OLA A H112  1 
HETATM 6104 H  H121  . OLA O 4 .   ? 28.93479  4.48684   35.87574 1.000 102.72560 ? 1214 OLA A H121  1 
HETATM 6105 H  H122  . OLA O 4 .   ? 28.34411  3.83535   37.15085 1.000 102.72560 ? 1214 OLA A H122  1 
HETATM 6106 H  H131  . OLA O 4 .   ? 28.77799  5.68562   38.42365 1.000 96.69640  ? 1214 OLA A H131  1 
HETATM 6107 H  H132  . OLA O 4 .   ? 29.72562  6.28437   37.35363 1.000 96.69640  ? 1214 OLA A H132  1 
HETATM 6108 H  H141  . OLA O 4 .   ? 27.53399  6.21963   35.98831 1.000 95.24057  ? 1214 OLA A H141  1 
HETATM 6109 H  H142  . OLA O 4 .   ? 28.00843  7.49422   36.72622 1.000 95.24057  ? 1214 OLA A H142  1 
HETATM 6110 H  H151  . OLA O 4 .   ? 26.58021  7.04235   38.53829 1.000 97.04507  ? 1214 OLA A H151  1 
HETATM 6111 H  H152  . OLA O 4 .   ? 26.24642  5.65410   37.94055 1.000 97.04507  ? 1214 OLA A H152  1 
HETATM 6112 C  C1    . OLA P 4 .   ? 41.18894  -17.19549 14.44595 1.000 109.45908 ? 1215 OLA A C1    1 
HETATM 6113 O  O1    . OLA P 4 .   ? 40.81163  -17.96975 13.54089 1.000 106.44636 ? 1215 OLA A O1    1 
HETATM 6114 O  O2    . OLA P 4 .   ? 41.01531  -17.35501 15.67356 1.000 107.43920 ? 1215 OLA A O2    1 
HETATM 6115 C  C2    . OLA P 4 .   ? 41.94450  -15.91657 14.02907 1.000 106.21356 ? 1215 OLA A C2    1 
HETATM 6116 C  C3    . OLA P 4 .   ? 41.28232  -14.59462 14.38070 1.000 101.84389 ? 1215 OLA A C3    1 
HETATM 6117 C  C4    . OLA P 4 .   ? 42.01641  -13.39631 13.79118 1.000 100.52934 ? 1215 OLA A C4    1 
HETATM 6118 C  C5    . OLA P 4 .   ? 41.09380  -12.22519 13.45684 1.000 92.12139  ? 1215 OLA A C5    1 
HETATM 6119 C  C6    . OLA P 4 .   ? 41.59399  -10.87539 13.95967 1.000 89.40367  ? 1215 OLA A C6    1 
HETATM 6120 C  C7    . OLA P 4 .   ? 40.81980  -9.68042  13.40717 1.000 91.28158  ? 1215 OLA A C7    1 
HETATM 6121 C  C8    . OLA P 4 .   ? 41.40781  -8.31743  13.76406 1.000 89.66845  ? 1215 OLA A C8    1 
HETATM 6122 C  C9    . OLA P 4 .   ? 40.77722  -7.23297  12.94039 1.000 96.25584  ? 1215 OLA A C9    1 
HETATM 6123 C  C10   . OLA P 4 .   ? 41.04126  -5.92687  12.96293 1.000 95.66811  ? 1215 OLA A C10   1 
HETATM 6124 C  C11   . OLA P 4 .   ? 42.04489  -5.22082  13.81544 1.000 95.86642  ? 1215 OLA A C11   1 
HETATM 6125 C  C12   . OLA P 4 .   ? 42.79022  -4.10299  13.07816 1.000 94.34554  ? 1215 OLA A C12   1 
HETATM 6126 C  C13   . OLA P 4 .   ? 43.37402  -3.04987  14.01107 1.000 88.12634  ? 1215 OLA A C13   1 
HETATM 6127 C  C14   . OLA P 4 .   ? 43.60325  -1.71733  13.30316 1.000 81.57030  ? 1215 OLA A C14   1 
HETATM 6128 C  C15   . OLA P 4 .   ? 43.76622  -0.50903  14.22466 1.000 79.83242  ? 1215 OLA A C15   1 
HETATM 6129 H  H21   . OLA P 4 .   ? 42.09735  -15.95214 13.07185 1.000 127.49949 ? 1215 OLA A H21   1 
HETATM 6130 H  H22   . OLA P 4 .   ? 42.83026  -15.94454 14.42347 1.000 127.49949 ? 1215 OLA A H22   1 
HETATM 6131 H  H31   . OLA P 4 .   ? 41.23443  -14.49468 15.34434 1.000 122.25588 ? 1215 OLA A H31   1 
HETATM 6132 H  H32   . OLA P 4 .   ? 40.36462  -14.59048 14.06651 1.000 122.25588 ? 1215 OLA A H32   1 
HETATM 6133 H  H41   . OLA P 4 .   ? 42.69920  -13.10603 14.41602 1.000 120.67843 ? 1215 OLA A H41   1 
HETATM 6134 H  H42   . OLA P 4 .   ? 42.48931  -13.67780 12.99241 1.000 120.67843 ? 1215 OLA A H42   1 
HETATM 6135 H  H51   . OLA P 4 .   ? 40.21302  -12.39202 13.82738 1.000 110.58889 ? 1215 OLA A H51   1 
HETATM 6136 H  H52   . OLA P 4 .   ? 40.96925  -12.17632 12.49611 1.000 110.58889 ? 1215 OLA A H52   1 
HETATM 6137 H  H61   . OLA P 4 .   ? 41.55300  -10.86794 14.92877 1.000 107.32762 ? 1215 OLA A H61   1 
HETATM 6138 H  H62   . OLA P 4 .   ? 42.53295  -10.78576 13.73336 1.000 107.32762 ? 1215 OLA A H62   1 
HETATM 6139 H  H71   . OLA P 4 .   ? 40.76478  -9.75140  12.44134 1.000 109.58111 ? 1215 OLA A H71   1 
HETATM 6140 H  H72   . OLA P 4 .   ? 39.90383  -9.71595  13.72442 1.000 109.58111 ? 1215 OLA A H72   1 
HETATM 6141 H  H81   . OLA P 4 .   ? 42.36789  -8.33815  13.62724 1.000 107.64535 ? 1215 OLA A H81   1 
HETATM 6142 H  H82   . OLA P 4 .   ? 41.27565  -8.15057  14.71042 1.000 107.64535 ? 1215 OLA A H82   1 
HETATM 6143 H  H9    . OLA P 4 .   ? 40.12417  -7.52636  12.34679 1.000 115.55022 ? 1215 OLA A H9    1 
HETATM 6144 H  H10   . OLA P 4 .   ? 40.55630  -5.37722  12.39057 1.000 114.84495 ? 1215 OLA A H10   1 
HETATM 6145 H  H111  . OLA P 4 .   ? 41.59570  -4.85403  14.59300 1.000 115.08293 ? 1215 OLA A H111  1 
HETATM 6146 H  H112  . OLA P 4 .   ? 42.68275  -5.86867  14.15357 1.000 115.08293 ? 1215 OLA A H112  1 
HETATM 6147 H  H121  . OLA P 4 .   ? 43.50031  -4.49279  12.54458 1.000 113.25787 ? 1215 OLA A H121  1 
HETATM 6148 H  H122  . OLA P 4 .   ? 42.18566  -3.67930  12.44896 1.000 113.25787 ? 1215 OLA A H122  1 
HETATM 6149 H  H131  . OLA P 4 .   ? 44.20512  -3.38911  14.37863 1.000 105.79483 ? 1215 OLA A H131  1 
HETATM 6150 H  H132  . OLA P 4 .   ? 42.77383  -2.93774  14.76479 1.000 105.79483 ? 1215 OLA A H132  1 
HETATM 6151 H  H141  . OLA P 4 .   ? 44.39042  -1.79623  12.74187 1.000 97.92758  ? 1215 OLA A H141  1 
HETATM 6152 H  H142  . OLA P 4 .   ? 42.86239  -1.55668  12.69799 1.000 97.92758  ? 1215 OLA A H142  1 
HETATM 6153 H  H151  . OLA P 4 .   ? 42.94308  -0.34187  14.70978 1.000 95.84212  ? 1215 OLA A H151  1 
HETATM 6154 H  H152  . OLA P 4 .   ? 44.42905  -0.73302  14.89671 1.000 95.84212  ? 1215 OLA A H152  1 
HETATM 6155 C  C1    . OLB Q 5 .   ? 2.56875   -8.28235  26.46832 0.794 74.11649  ? 1216 OLB A C1    1 
HETATM 6156 C  C2    . OLB Q 5 .   ? 2.95139   -7.09621  25.62879 0.794 67.57023  ? 1216 OLB A C2    1 
HETATM 6157 C  C3    . OLB Q 5 .   ? 2.96041   -5.79661  26.41443 0.794 64.52704  ? 1216 OLB A C3    1 
HETATM 6158 C  C4    . OLB Q 5 .   ? 3.64618   -4.67012  25.65474 0.794 68.56702  ? 1216 OLB A C4    1 
HETATM 6159 C  C5    . OLB Q 5 .   ? 3.02490   -3.31091  25.94604 0.794 65.07375  ? 1216 OLB A C5    1 
HETATM 6160 O  O19   . OLB Q 5 .   ? 2.67585   -8.33995  27.66907 0.794 80.38290  ? 1216 OLB A O19   1 
HETATM 6161 O  O20   . OLB Q 5 .   ? 2.08594   -9.27192  25.72229 0.794 72.23865  ? 1216 OLB A O20   1 
HETATM 6162 C  C21   . OLB Q 5 .   ? 1.40785   -10.34434 26.37638 0.794 73.79758  ? 1216 OLB A C21   1 
HETATM 6163 C  C22   . OLB Q 5 .   ? 2.31462   -11.56355 26.35380 0.794 73.19148  ? 1216 OLB A C22   1 
HETATM 6164 O  O23   . OLB Q 5 .   ? 3.52415   -11.34791 27.04107 0.794 75.81584  ? 1216 OLB A O23   1 
HETATM 6165 C  C24   . OLB Q 5 .   ? 1.54297   -12.76221 26.88614 0.794 78.08889  ? 1216 OLB A C24   1 
HETATM 6166 O  O25   . OLB Q 5 .   ? 1.96859   -13.90848 26.19371 0.794 86.73691  ? 1216 OLB A O25   1 
HETATM 6167 C  C6    . OLB Q 5 .   ? 4.02721   -2.16836  25.87002 0.794 71.33585  ? 1216 OLB A C6    1 
HETATM 6168 C  C7    . OLB Q 5 .   ? 3.37475   -0.83272  25.53862 0.794 76.50130  ? 1216 OLB A C7    1 
HETATM 6169 C  C8    . OLB Q 5 .   ? 4.34226   0.34237   25.66648 0.794 82.98509  ? 1216 OLB A C8    1 
HETATM 6170 C  C9    . OLB Q 5 .   ? 3.78538   1.60093   25.07623 0.794 90.51205  ? 1216 OLB A C9    1 
HETATM 6171 C  C10   . OLB Q 5 .   ? 3.89994   2.84203   25.55092 0.794 98.00889  ? 1216 OLB A C10   1 
HETATM 6172 C  C11   . OLB Q 5 .   ? 3.33170   4.08978   24.94539 0.794 87.53048  ? 1216 OLB A C11   1 
HETATM 6173 H  H2    . OLB Q 5 .   ? 2.33813   -7.04056  24.87931 0.794 81.12749  ? 1216 OLB A H2    1 
HETATM 6174 H  H2A   . OLB Q 5 .   ? 3.82187   -7.26660  25.23619 0.794 81.12749  ? 1216 OLB A H2A   1 
HETATM 6175 H  H3    . OLB Q 5 .   ? 3.40954   -5.93082  27.26364 0.794 77.47567  ? 1216 OLB A H3    1 
HETATM 6176 H  H3A   . OLB Q 5 .   ? 2.05025   -5.53470  26.62399 0.794 77.47567  ? 1216 OLB A H3A   1 
HETATM 6177 H  H4    . OLB Q 5 .   ? 3.60455   -4.84543  24.70162 0.794 82.32364  ? 1216 OLB A H4    1 
HETATM 6178 H  H4A   . OLB Q 5 .   ? 4.58889   -4.64851  25.88218 0.794 82.32364  ? 1216 OLB A H4A   1 
HETATM 6179 H  H5    . OLB Q 5 .   ? 2.61921   -3.32532  26.82702 0.794 78.13172  ? 1216 OLB A H5    1 
HETATM 6180 H  H5A   . OLB Q 5 .   ? 2.30206   -3.14735  25.32022 0.794 78.13172  ? 1216 OLB A H5A   1 
HETATM 6181 H  H21   . OLB Q 5 .   ? 1.19776   -10.09505 27.28995 0.794 88.60031  ? 1216 OLB A H21   1 
HETATM 6182 H  H21A  . OLB Q 5 .   ? 0.57266   -10.53461 25.92122 0.794 88.60031  ? 1216 OLB A H21A  1 
HETATM 6183 H  H22   . OLB Q 5 .   ? 2.56777   -11.74211 25.43460 0.794 87.87299  ? 1216 OLB A H22   1 
HETATM 6184 H  HO23  . OLB Q 5 .   ? 4.00367   -12.04681 26.97697 0.794 91.02223  ? 1216 OLB A HO23  1 
HETATM 6185 H  H24   . OLB Q 5 .   ? 0.59279   -12.60547 26.76998 0.794 93.74989  ? 1216 OLB A H24   1 
HETATM 6186 H  H24A  . OLB Q 5 .   ? 1.69810   -12.84165 27.84036 0.794 93.74989  ? 1216 OLB A H24A  1 
HETATM 6187 H  HO25  . OLB Q 5 .   ? 1.46677   -14.55511 26.42294 0.794 104.12750 ? 1216 OLB A HO25  1 
HETATM 6188 H  H16   . OLB Q 5 .   ? 4.70135   -2.37052  25.20251 0.794 85.64623  ? 1216 OLB A H16   1 
HETATM 6189 H  H17   . OLB Q 5 .   ? 4.50046   -2.09376  26.71345 0.794 85.64623  ? 1216 OLB A H17   1 
HETATM 6190 H  H18   . OLB Q 5 .   ? 3.01971   -0.86034  24.63636 0.794 91.84477  ? 1216 OLB A H18   1 
HETATM 6191 H  H19   . OLB Q 5 .   ? 2.61491   -0.68893  26.12416 0.794 91.84477  ? 1216 OLB A H19   1 
HETATM 6192 H  H20   . OLB Q 5 .   ? 4.55314   0.47403   26.60408 0.794 99.62532  ? 1216 OLB A H20   1 
HETATM 6193 H  H211  . OLB Q 5 .   ? 5.17844   0.10825   25.23417 0.794 99.62532  ? 1216 OLB A H211  1 
HETATM 6194 H  H221  . OLB Q 5 .   ? 3.30695   1.48503   24.28720 0.794 108.65767 ? 1216 OLB A H221  1 
HETATM 6195 C  C12   . OLB Q 5 .   ? 4.12026   4.53374   23.71171 0.794 86.61826  ? 1216 OLB A C12   1 
HETATM 6196 H  H23   . OLB Q 5 .   ? 4.37935   2.96185   26.33877 0.794 117.65388 ? 1216 OLB A H23   1 
HETATM 6197 H  H241  . OLB Q 5 .   ? 3.33198   4.81380   25.59091 0.794 105.07979 ? 1216 OLB A H241  1 
HETATM 6198 H  H25   . OLB Q 5 .   ? 2.40580   3.95466   24.68972 0.794 105.07979 ? 1216 OLB A H25   1 
HETATM 6199 H  H26   . OLB Q 5 .   ? 4.98506   4.87646   23.98594 0.794 103.98513 ? 1216 OLB A H26   1 
HETATM 6200 H  H27   . OLB Q 5 .   ? 4.30039   3.75622   23.16111 0.794 103.98513 ? 1216 OLB A H27   1 
HETATM 6201 C  C1    . OLB R 5 .   ? 35.61103  19.79089  18.04048 0.781 90.13783  ? 1217 OLB A C1    1 
HETATM 6202 C  C2    . OLB R 5 .   ? 35.09644  18.42598  18.41431 0.781 86.40030  ? 1217 OLB A C2    1 
HETATM 6203 C  C3    . OLB R 5 .   ? 36.19389  17.39378  18.61903 0.781 84.06475  ? 1217 OLB A C3    1 
HETATM 6204 C  C4    . OLB R 5 .   ? 35.63761  16.02123  18.97786 0.781 81.00023  ? 1217 OLB A C4    1 
HETATM 6205 C  C5    . OLB R 5 .   ? 35.13343  15.25970  17.75765 0.781 81.91927  ? 1217 OLB A C5    1 
HETATM 6206 O  O19   . OLB R 5 .   ? 36.72992  20.19423  18.23902 0.781 96.19188  ? 1217 OLB A O19   1 
HETATM 6207 O  O20   . OLB R 5 .   ? 34.67881  20.52446  17.44102 0.781 84.56158  ? 1217 OLB A O20   1 
HETATM 6208 C  C21   . OLB R 5 .   ? 33.78384  21.28775  18.24866 0.781 85.99894  ? 1217 OLB A C21   1 
HETATM 6209 C  C22   . OLB R 5 .   ? 34.57244  22.41751  18.88832 0.781 88.76839  ? 1217 OLB A C22   1 
HETATM 6210 O  O23   . OLB R 5 .   ? 35.34044  23.12708  17.94769 0.781 89.08266  ? 1217 OLB A O23   1 
HETATM 6211 C  C24   . OLB R 5 .   ? 33.61538  23.31248  19.66136 0.781 85.59585  ? 1217 OLB A C24   1 
HETATM 6212 O  O25   . OLB R 5 .   ? 34.33960  24.39782  20.18340 0.781 86.41893  ? 1217 OLB A O25   1 
HETATM 6213 C  C6    . OLB R 5 .   ? 35.85869  13.94280  17.51145 0.781 78.42337  ? 1217 OLB A C6    1 
HETATM 6214 C  C7    . OLB R 5 .   ? 35.42942  12.81824  18.44625 0.781 79.70455  ? 1217 OLB A C7    1 
HETATM 6215 C  C8    . OLB R 5 .   ? 35.45639  11.44361  17.77499 0.781 73.87859  ? 1217 OLB A C8    1 
HETATM 6216 C  C9    . OLB R 5 .   ? 36.43506  10.48290  18.38367 0.781 81.39528  ? 1217 OLB A C9    1 
HETATM 6217 C  C10   . OLB R 5 .   ? 36.74343  10.31687  19.67109 0.781 77.31397  ? 1217 OLB A C10   1 
HETATM 6218 C  C11   . OLB R 5 .   ? 37.72916  9.34082   20.24352 0.781 77.57545  ? 1217 OLB A C11   1 
HETATM 6219 H  H2    . OLB R 5 .   ? 34.55887  18.51494  19.21681 0.781 103.72357 ? 1217 OLB A H2    1 
HETATM 6220 H  H2A   . OLB R 5 .   ? 34.48052  18.13548  17.72355 0.781 103.72357 ? 1217 OLB A H2A   1 
HETATM 6221 H  H3    . OLB R 5 .   ? 36.79394  17.68986  19.32130 0.781 100.92091 ? 1217 OLB A H3    1 
HETATM 6222 H  H3A   . OLB R 5 .   ? 36.72913  17.32188  17.81327 0.781 100.92091 ? 1217 OLB A H3A   1 
HETATM 6223 H  H4    . OLB R 5 .   ? 36.32158  15.49756  19.42380 0.781 97.24350  ? 1217 OLB A H4    1 
HETATM 6224 H  H4A   . OLB R 5 .   ? 34.91497  16.11831  19.61760 0.781 97.24350  ? 1217 OLB A H4A   1 
HETATM 6225 H  H5    . OLB R 5 .   ? 34.18451  15.08678  17.86037 0.781 98.34634  ? 1217 OLB A H5    1 
HETATM 6226 H  H5A   . OLB R 5 .   ? 35.22027  15.82314  16.97285 0.781 98.34634  ? 1217 OLB A H5A   1 
HETATM 6227 H  H21   . OLB R 5 .   ? 33.06490  21.64244  17.70258 0.781 103.24194 ? 1217 OLB A H21   1 
HETATM 6228 H  H21A  . OLB R 5 .   ? 33.38767  20.72222  18.92993 0.781 103.24194 ? 1217 OLB A H21A  1 
HETATM 6229 H  H22   . OLB R 5 .   ? 35.20923  22.03792  19.51387 0.781 106.56528 ? 1217 OLB A H22   1 
HETATM 6230 H  HO23  . OLB R 5 .   ? 35.85211  23.66478  18.36190 0.781 106.94240 ? 1217 OLB A HO23  1 
HETATM 6231 H  H24   . OLB R 5 .   ? 33.19288  22.79329  20.36338 0.781 102.75823 ? 1217 OLB A H24   1 
HETATM 6232 H  H24A  . OLB R 5 .   ? 32.90726  23.60716  19.06753 0.781 102.75823 ? 1217 OLB A H24A  1 
HETATM 6233 H  HO25  . OLB R 5 .   ? 33.78422  24.94712  20.51856 0.781 103.74593 ? 1217 OLB A HO25  1 
HETATM 6234 H  H16   . OLB R 5 .   ? 36.81456  14.08108  17.60131 0.781 94.15126  ? 1217 OLB A H16   1 
HETATM 6235 H  H17   . OLB R 5 .   ? 35.71437  13.66353  16.59380 0.781 94.15126  ? 1217 OLB A H17   1 
HETATM 6236 H  H18   . OLB R 5 .   ? 34.53496  12.99626  18.77664 0.781 95.68868  ? 1217 OLB A H18   1 
HETATM 6237 H  H19   . OLB R 5 .   ? 36.00806  12.80638  19.22467 0.781 95.68868  ? 1217 OLB A H19   1 
HETATM 6238 H  H20   . OLB R 5 .   ? 35.65789  11.56788  16.83432 0.781 88.69753  ? 1217 OLB A H20   1 
HETATM 6239 H  H211  . OLB R 5 .   ? 34.56200  11.06982  17.81023 0.781 88.69753  ? 1217 OLB A H211  1 
HETATM 6240 H  H221  . OLB R 5 .   ? 36.87465  9.94061   17.76919 0.781 97.71755  ? 1217 OLB A H221  1 
HETATM 6241 C  C12   . OLB R 5 .   ? 37.57383  9.16717   21.75756 0.781 81.53388  ? 1217 OLB A C12   1 
HETATM 6242 H  H23   . OLB R 5 .   ? 36.30954  10.85625  20.29214 0.781 92.81998  ? 1217 OLB A H23   1 
HETATM 6243 H  H241  . OLB R 5 .   ? 38.63701  9.62849   20.05927 0.781 93.13375  ? 1217 OLB A H241  1 
HETATM 6244 C  C13   . OLB R 5 .   ? 37.74610  7.72344   22.21319 0.781 73.15862  ? 1217 OLB A C13   1 
HETATM 6245 H  H25   . OLB R 5 .   ? 37.62923  8.47231   19.82327 0.781 93.13375  ? 1217 OLB A H25   1 
HETATM 6246 H  H26   . OLB R 5 .   ? 36.69976  9.48917   22.02812 0.781 97.88387  ? 1217 OLB A H26   1 
HETATM 6247 H  H27   . OLB R 5 .   ? 38.22141  9.72868   22.21171 0.781 97.88387  ? 1217 OLB A H27   1 
HETATM 6248 H  H28   . OLB R 5 .   ? 38.46151  7.30451   21.70965 0.781 87.83356  ? 1217 OLB A H28   1 
HETATM 6249 H  H29   . OLB R 5 .   ? 36.94078  7.22512   22.00187 0.781 87.83356  ? 1217 OLB A H29   1 
HETATM 6250 C  C18   . OLC S 6 .   ? 41.04809  5.54806   16.98010 0.639 95.00891  ? 1218 OLC A C18   1 
HETATM 6251 C  C10   . OLC S 6 .   ? 38.42691  -3.14007  15.24257 0.639 71.15239  ? 1218 OLC A C10   1 
HETATM 6252 C  C9    . OLC S 6 .   ? 37.95234  -4.34405  15.53646 0.639 68.55685  ? 1218 OLC A C9    1 
HETATM 6253 C  C17   . OLC S 6 .   ? 40.87186  4.59670   15.80483 0.639 85.79349  ? 1218 OLC A C17   1 
HETATM 6254 C  C11   . OLC S 6 .   ? 38.58201  -1.98969  16.18383 0.639 71.20515  ? 1218 OLC A C11   1 
HETATM 6255 C  C8    . OLC S 6 .   ? 37.46099  -4.79275  16.87393 0.639 69.20044  ? 1218 OLC A C8    1 
HETATM 6256 C  C24   . OLC S 6 .   ? 39.54001  -17.66862 19.26059 0.639 90.23565  ? 1218 OLC A C24   1 
HETATM 6257 C  C16   . OLC S 6 .   ? 41.56966  3.25942   16.02278 0.639 85.58769  ? 1218 OLC A C16   1 
HETATM 6258 C  C12   . OLC S 6 .   ? 38.71642  -0.66214  15.44461 0.639 72.01139  ? 1218 OLC A C12   1 
HETATM 6259 C  C7    . OLC S 6 .   ? 36.73262  -6.13119  16.78983 0.639 72.46397  ? 1218 OLC A C7    1 
HETATM 6260 C  C15   . OLC S 6 .   ? 40.98359  2.12436   15.19328 0.639 83.69941  ? 1218 OLC A C15   1 
HETATM 6261 C  C13   . OLC S 6 .   ? 40.16679  -0.27998  15.18453 0.639 76.73839  ? 1218 OLC A C13   1 
HETATM 6262 C  C6    . OLC S 6 .   ? 37.63437  -7.27568  16.35687 0.639 75.42854  ? 1218 OLC A C6    1 
HETATM 6263 C  C14   . OLC S 6 .   ? 40.64536  0.89580   16.02766 0.639 79.63208  ? 1218 OLC A C14   1 
HETATM 6264 C  C5    . OLC S 6 .   ? 37.73268  -8.37903  17.40154 0.639 74.86295  ? 1218 OLC A C5    1 
HETATM 6265 C  C4    . OLC S 6 .   ? 38.04051  -9.73308  16.78232 0.639 80.00509  ? 1218 OLC A C4    1 
HETATM 6266 C  C3    . OLC S 6 .   ? 38.39987  -10.79082 17.81522 0.639 83.10943  ? 1218 OLC A C3    1 
HETATM 6267 C  C2    . OLC S 6 .   ? 38.81111  -12.09133 17.14510 0.639 83.86042  ? 1218 OLC A C2    1 
HETATM 6268 C  C21   . OLC S 6 .   ? 39.87007  -15.35651 18.46835 0.639 86.38743  ? 1218 OLC A C21   1 
HETATM 6269 C  C1    . OLC S 6 .   ? 39.48045  -13.06122 18.07679 0.639 84.46781  ? 1218 OLC A C1    1 
HETATM 6270 C  C22   . OLC S 6 .   ? 38.95055  -16.56702 18.39095 0.639 88.67215  ? 1218 OLC A C22   1 
HETATM 6271 O  O19   . OLC S 6 .   ? 40.10368  -12.75498 19.06251 0.639 87.55369  ? 1218 OLC A O19   1 
HETATM 6272 O  O25   . OLC S 6 .   ? 38.75975  -17.81262 20.42197 0.639 88.98194  ? 1218 OLC A O25   1 
HETATM 6273 O  O23   . OLC S 6 .   ? 37.61833  -16.24797 18.70148 0.639 88.58771  ? 1218 OLC A O23   1 
HETATM 6274 O  O20   . OLC S 6 .   ? 39.29735  -14.31700 17.68151 0.639 85.77095  ? 1218 OLC A O20   1 
HETATM 6275 H  H18   . OLC S 6 .   ? 41.98692  5.72340   17.14969 0.639 114.05391 ? 1218 OLC A H18   1 
HETATM 6276 H  H18A  . OLC S 6 .   ? 40.66476  5.17703   17.79022 0.639 114.05391 ? 1218 OLC A H18A  1 
HETATM 6277 H  H18B  . OLC S 6 .   ? 40.61387  6.39843   16.80916 0.639 114.05391 ? 1218 OLC A H18B  1 
HETATM 6278 H  H10   . OLC S 6 .   ? 38.69442  -2.97980  14.36641 0.639 85.42609  ? 1218 OLC A H10   1 
HETATM 6279 H  H9    . OLC S 6 .   ? 37.91521  -4.97956  14.85848 0.639 82.31144  ? 1218 OLC A H9    1 
HETATM 6280 H  H17   . OLC S 6 .   ? 41.21424  5.01009   14.99688 0.639 102.99541 ? 1218 OLC A H17   1 
HETATM 6281 H  H17A  . OLC S 6 .   ? 39.92684  4.44441   15.64783 0.639 102.99541 ? 1218 OLC A H17A  1 
HETATM 6282 H  H11   . OLC S 6 .   ? 37.82093  -1.94625  16.78364 0.639 85.48940  ? 1218 OLC A H11   1 
HETATM 6283 H  H11A  . OLC S 6 .   ? 39.36113  -2.12314  16.74602 0.639 85.48940  ? 1218 OLC A H11A  1 
HETATM 6284 H  H8    . OLC S 6 .   ? 38.20554  -4.87216  17.49056 0.639 83.08374  ? 1218 OLC A H8    1 
HETATM 6285 H  H8A   . OLC S 6 .   ? 36.86324  -4.12644  17.24761 0.639 83.08374  ? 1218 OLC A H8A   1 
HETATM 6286 H  H24   . OLC S 6 .   ? 39.56962  -18.48949 18.74465 0.639 108.32600 ? 1218 OLC A H24   1 
HETATM 6287 H  H24A  . OLC S 6 .   ? 40.45856  -17.43959 19.47205 0.639 108.32600 ? 1218 OLC A H24A  1 
HETATM 6288 H  H16   . OLC S 6 .   ? 42.51271  3.35291   15.81586 0.639 102.74845 ? 1218 OLC A H16   1 
HETATM 6289 H  H16A  . OLC S 6 .   ? 41.52520  3.02456   16.96287 0.639 102.74845 ? 1218 OLC A H16A  1 
HETATM 6290 H  H12   . OLC S 6 .   ? 38.28371  0.03825   15.95754 0.639 86.45689  ? 1218 OLC A H12   1 
HETATM 6291 H  H12A  . OLC S 6 .   ? 38.23832  -0.71191  14.60209 0.639 86.45689  ? 1218 OLC A H12A  1 
HETATM 6292 H  H7    . OLC S 6 .   ? 35.99051  -6.05190  16.17025 0.639 86.99998  ? 1218 OLC A H7    1 
HETATM 6293 H  H7A   . OLC S 6 .   ? 36.34179  -6.33627  17.65360 0.639 86.99998  ? 1218 OLC A H7A   1 
HETATM 6294 H  H15   . OLC S 6 .   ? 40.18550  2.43622   14.73864 0.639 100.48251 ? 1218 OLC A H15   1 
HETATM 6295 H  H15A  . OLC S 6 .   ? 41.61043  1.87851   14.49506 0.639 100.48251 ? 1218 OLC A H15A  1 
HETATM 6296 H  H13   . OLC S 6 .   ? 40.27835  -0.06547  14.24515 0.639 92.12929  ? 1218 OLC A H13   1 
HETATM 6297 H  H13A  . OLC S 6 .   ? 40.73585  -1.04697  15.35423 0.639 92.12929  ? 1218 OLC A H13A  1 
HETATM 6298 H  H6    . OLC S 6 .   ? 38.52204  -6.93385  16.16688 0.639 90.55746  ? 1218 OLC A H6    1 
HETATM 6299 H  H6A   . OLC S 6 .   ? 37.30478  -7.65010  15.52495 0.639 90.55746  ? 1218 OLC A H6A   1 
HETATM 6300 H  H14   . OLC S 6 .   ? 39.96284  1.12330   16.67828 0.639 95.60172  ? 1218 OLC A H14   1 
HETATM 6301 H  H14A  . OLC S 6 .   ? 41.42380  0.62748   16.54044 0.639 95.60172  ? 1218 OLC A H14A  1 
HETATM 6302 H  H5    . OLC S 6 .   ? 36.90204  -8.43216  17.89965 0.639 89.87875  ? 1218 OLC A H5    1 
HETATM 6303 H  H5A   . OLC S 6 .   ? 38.41947  -8.15551  18.04904 0.639 89.87875  ? 1218 OLC A H5A   1 
HETATM 6304 H  H4    . OLC S 6 .   ? 37.27544  -10.03476 16.26797 0.639 96.04932  ? 1218 OLC A H4    1 
HETATM 6305 H  H4A   . OLC S 6 .   ? 38.77095  -9.64116  16.15072 0.639 96.04932  ? 1218 OLC A H4A   1 
HETATM 6306 H  H3    . OLC S 6 .   ? 37.64253  -10.94559 18.40119 0.639 99.77454  ? 1218 OLC A H3    1 
HETATM 6307 H  H3A   . OLC S 6 .   ? 39.12029  -10.46629 18.37787 0.639 99.77454  ? 1218 OLC A H3A   1 
HETATM 6308 H  H2    . OLC S 6 .   ? 38.04259  -12.53540 16.75383 0.639 100.67572 ? 1218 OLC A H2    1 
HETATM 6309 H  H2A   . OLC S 6 .   ? 39.41589  -11.92187 16.40590 0.639 100.67572 ? 1218 OLC A H2A   1 
HETATM 6310 H  H21   . OLC S 6 .   ? 40.75293  -15.57731 18.13263 0.639 103.70814 ? 1218 OLC A H21   1 
HETATM 6311 H  H21A  . OLC S 6 .   ? 39.96725  -15.06069 19.38702 0.639 103.70814 ? 1218 OLC A H21A  1 
HETATM 6312 H  H22   . OLC S 6 .   ? 38.91418  -16.88956 17.47687 0.639 106.44980 ? 1218 OLC A H22   1 
HETATM 6313 H  HO25  . OLC S 6 .   ? 39.24112  -17.60120 21.08986 0.639 106.82154 ? 1218 OLC A HO25  1 
HETATM 6314 H  HO23  . OLC S 6 .   ? 37.11008  -16.83856 18.36179 0.639 106.34846 ? 1218 OLC A HO23  1 
HETATM 6315 C  C10   . OLC T 6 .   ? 34.14145  9.39802   23.40988 0.729 67.90881  ? 1219 OLC A C10   1 
HETATM 6316 C  C9    . OLC T 6 .   ? 34.11740  10.70203  23.14679 0.729 64.15985  ? 1219 OLC A C9    1 
HETATM 6317 C  C11   . OLC T 6 .   ? 33.85434  8.70665   24.70520 0.729 65.84500  ? 1219 OLC A C11   1 
HETATM 6318 C  C8    . OLC T 6 .   ? 33.80732  11.82730  24.08010 0.729 65.65611  ? 1219 OLC A C8    1 
HETATM 6319 C  C24   . OLC T 6 .   ? 32.28047  24.13680  25.22024 0.729 86.96536  ? 1219 OLC A C24   1 
HETATM 6320 C  C12   . OLC T 6 .   ? 34.18419  7.21614   24.62967 0.729 67.06666  ? 1219 OLC A C12   1 
HETATM 6321 C  C7    . OLC T 6 .   ? 32.73773  12.75137  23.49787 0.729 64.22842  ? 1219 OLC A C7    1 
HETATM 6322 C  C6    . OLC T 6 .   ? 33.30614  13.94873  22.74867 0.729 63.22857  ? 1219 OLC A C6    1 
HETATM 6323 C  C5    . OLC T 6 .   ? 32.29551  15.08481  22.64940 0.729 71.00776  ? 1219 OLC A C5    1 
HETATM 6324 C  C4    . OLC T 6 .   ? 32.83992  16.33261  21.96726 0.729 73.51060  ? 1219 OLC A C4    1 
HETATM 6325 C  C3    . OLC T 6 .   ? 31.98442  17.56579  22.23423 0.729 73.27533  ? 1219 OLC A C3    1 
HETATM 6326 C  C2    . OLC T 6 .   ? 32.82306  18.82696  22.37970 0.729 81.55491  ? 1219 OLC A C2    1 
HETATM 6327 C  C21   . OLC T 6 .   ? 32.07445  21.92354  24.11662 0.729 83.28673  ? 1219 OLC A C21   1 
HETATM 6328 C  C1    . OLC T 6 .   ? 32.01170  20.05624  22.68746 0.729 80.93824  ? 1219 OLC A C1    1 
HETATM 6329 C  C22   . OLC T 6 .   ? 32.93614  23.16926  24.24558 0.729 85.11704  ? 1219 OLC A C22   1 
HETATM 6330 O  O19   . OLC T 6 .   ? 30.83560  20.18876  22.45499 0.729 84.17855  ? 1219 OLC A O19   1 
HETATM 6331 O  O25   . OLC T 6 .   ? 32.81690  25.42310  25.03299 0.729 87.63479  ? 1219 OLC A O25   1 
HETATM 6332 O  O23   . OLC T 6 .   ? 34.26307  22.85581  24.58908 0.729 93.61927  ? 1219 OLC A O23   1 
HETATM 6333 O  O20   . OLC T 6 .   ? 32.74711  21.00177  23.26248 0.729 79.31017  ? 1219 OLC A O20   1 
HETATM 6334 H  H10   . OLC T 6 .   ? 34.36366  8.82908   22.70857 0.729 81.53379  ? 1219 OLC A H10   1 
HETATM 6335 H  H9    . OLC T 6 .   ? 34.31629  10.96397  22.27689 0.729 77.03504  ? 1219 OLC A H9    1 
HETATM 6336 H  H11   . OLC T 6 .   ? 34.36602  9.11368   25.42172 0.729 79.05722  ? 1219 OLC A H11   1 
HETATM 6337 H  H11A  . OLC T 6 .   ? 32.92071  8.81807   24.94359 0.729 79.05722  ? 1219 OLC A H11A  1 
HETATM 6338 H  H8    . OLC T 6 .   ? 33.50245  11.47884  24.93247 0.729 78.83055  ? 1219 OLC A H8    1 
HETATM 6339 H  H8A   . OLC T 6 .   ? 34.61051  12.33951  24.26290 0.729 78.83055  ? 1219 OLC A H8A   1 
HETATM 6340 H  H24   . OLC T 6 .   ? 32.42788  23.81522  26.12343 0.729 104.40165 ? 1219 OLC A H24   1 
HETATM 6341 H  H24A  . OLC T 6 .   ? 31.32177  24.12362  25.07318 0.729 104.40165 ? 1219 OLC A H24A  1 
HETATM 6342 H  H12   . OLC T 6 .   ? 33.55911  6.77927   24.02905 0.729 80.52321  ? 1219 OLC A H12   1 
HETATM 6343 H  H12A  . OLC T 6 .   ? 35.06090  7.10643   24.22972 0.729 80.52321  ? 1219 OLC A H12A  1 
HETATM 6344 H  H7    . OLC T 6 .   ? 32.16835  12.24021  22.90170 0.729 77.11731  ? 1219 OLC A H7    1 
HETATM 6345 H  H7A   . OLC T 6 .   ? 32.16484  13.06393  24.21550 0.729 77.11731  ? 1219 OLC A H7A   1 
HETATM 6346 H  H6    . OLC T 6 .   ? 34.10767  14.26426  23.19464 0.729 75.91750  ? 1219 OLC A H6    1 
HETATM 6347 H  H6A   . OLC T 6 .   ? 33.58039  13.67845  21.85837 0.729 75.91750  ? 1219 OLC A H6A   1 
HETATM 6348 H  H5    . OLC T 6 .   ? 31.51247  14.77577  22.16749 0.729 85.25252  ? 1219 OLC A H5    1 
HETATM 6349 H  H5A   . OLC T 6 .   ? 31.98761  15.31830  23.53911 0.729 85.25252  ? 1219 OLC A H5A   1 
HETATM 6350 H  H4    . OLC T 6 .   ? 32.89713  16.18140  21.01083 0.729 88.25594  ? 1219 OLC A H4    1 
HETATM 6351 H  H4A   . OLC T 6 .   ? 33.74678  16.49847  22.26892 0.729 88.25594  ? 1219 OLC A H4A   1 
HETATM 6352 H  H3    . OLC T 6 .   ? 31.34825  17.67876  21.51075 0.729 87.97361  ? 1219 OLC A H3    1 
HETATM 6353 H  H3A   . OLC T 6 .   ? 31.46207  17.42673  23.03966 0.729 87.97361  ? 1219 OLC A H3A   1 
HETATM 6354 H  H2    . OLC T 6 .   ? 33.48406  18.72217  23.08183 0.729 97.90911  ? 1219 OLC A H2    1 
HETATM 6355 H  H2A   . OLC T 6 .   ? 33.33008  18.99885  21.57082 0.729 97.90911  ? 1219 OLC A H2A   1 
HETATM 6356 H  H21   . OLC T 6 .   ? 31.20765  22.14716  23.74306 0.729 99.98730  ? 1219 OLC A H21   1 
HETATM 6357 H  H21A  . OLC T 6 .   ? 31.92770  21.52035  24.98657 0.729 99.98730  ? 1219 OLC A H21A  1 
HETATM 6358 H  H22   . OLC T 6 .   ? 32.98444  23.60664  23.38114 0.729 102.18367 ? 1219 OLC A H22   1 
HETATM 6359 H  HO25  . OLC T 6 .   ? 32.43683  25.94885  25.58220 0.729 105.20496 ? 1219 OLC A HO25  1 
HETATM 6360 H  HO23  . OLC T 6 .   ? 34.78578  23.35636  24.14330 0.729 112.38634 ? 1219 OLC A HO23  1 
HETATM 6361 N  N1    . JQ9 U 7 .   ? 21.16359  -4.36124  18.67939 1.000 47.82770  ? 1220 JQ9 A N1    1 
HETATM 6362 C  C12   . JQ9 U 7 .   ? 21.03912  -3.16130  20.85138 1.000 60.81023  ? 1220 JQ9 A C12   1 
HETATM 6363 O  O2    . JQ9 U 7 .   ? 23.10164  -3.52247  17.81705 1.000 52.14952  ? 1220 JQ9 A O2    1 
HETATM 6364 C  C2    . JQ9 U 7 .   ? 22.32950  -4.45584  17.92411 1.000 48.12968  ? 1220 JQ9 A C2    1 
HETATM 6365 N  N3    . JQ9 U 7 .   ? 22.58009  -5.65443  17.29982 1.000 53.81354  ? 1220 JQ9 A N3    1 
HETATM 6366 C  C21   . JQ9 U 7 .   ? 23.78929  -5.81273  16.49352 1.000 51.83417  ? 1220 JQ9 A C21   1 
HETATM 6367 C  C22   . JQ9 U 7 .   ? 24.91964  -6.45374  17.28179 1.000 54.33196  ? 1220 JQ9 A C22   1 
HETATM 6368 C  C4    . JQ9 U 7 .   ? 21.69557  -6.68718  17.43675 1.000 49.20777  ? 1220 JQ9 A C4    1 
HETATM 6369 N  N9    . JQ9 U 7 .   ? 21.79782  -7.90379  16.89636 1.000 45.63601  ? 1220 JQ9 A N9    1 
HETATM 6370 C  C8    . JQ9 U 7 .   ? 20.70517  -8.55314  17.30850 1.000 52.84388  ? 1220 JQ9 A C8    1 
HETATM 6371 N  N7    . JQ9 U 7 .   ? 19.92211  -7.78135  18.09331 1.000 50.71560  ? 1220 JQ9 A N7    1 
HETATM 6372 C  C7    . JQ9 U 7 .   ? 18.66450  -8.12116  18.73063 1.000 49.88119  ? 1220 JQ9 A C7    1 
HETATM 6373 C  C5    . JQ9 U 7 .   ? 20.55219  -6.56350  18.18598 1.000 46.31254  ? 1220 JQ9 A C5    1 
HETATM 6374 C  C6    . JQ9 U 7 .   ? 20.20886  -5.37006  18.87031 1.000 45.48861  ? 1220 JQ9 A C6    1 
HETATM 6375 O  O6    . JQ9 U 7 .   ? 19.22058  -5.19006  19.56130 1.000 47.05223  ? 1220 JQ9 A O6    1 
HETATM 6376 C  C11   . JQ9 U 7 .   ? 20.88805  -3.08454  19.33978 1.000 48.68200  ? 1220 JQ9 A C11   1 
HETATM 6377 C  CA    . JQ9 U 7 .   ? 20.38467  -9.91863  16.96950 1.000 54.25963  ? 1220 JQ9 A CA    1 
HETATM 6378 C  CB    . JQ9 U 7 .   ? 21.11189  -10.64690 16.10951 1.000 57.87112  ? 1220 JQ9 A CB    1 
HETATM 6379 C  "C1'" . JQ9 U 7 .   ? 20.84881  -12.02664 15.72769 1.000 62.96765  ? 1220 JQ9 A "C1'" 1 
HETATM 6380 C  "C6'" . JQ9 U 7 .   ? 19.67302  -12.69788 16.04422 1.000 60.48233  ? 1220 JQ9 A "C6'" 1 
HETATM 6381 C  "C5'" . JQ9 U 7 .   ? 19.48006  -14.01521 15.65819 1.000 62.28691  ? 1220 JQ9 A "C5'" 1 
HETATM 6382 C  "C4'" . JQ9 U 7 .   ? 20.45965  -14.69583 14.94895 1.000 69.18206  ? 1220 JQ9 A "C4'" 1 
HETATM 6383 O  "O4'" . JQ9 U 7 .   ? 20.38203  -15.96594 14.52860 1.000 70.22860  ? 1220 JQ9 A "O4'" 1 
HETATM 6384 C  "C8'" . JQ9 U 7 .   ? 19.15179  -16.66849 14.66267 1.000 76.43860  ? 1220 JQ9 A "C8'" 1 
HETATM 6385 C  "C3'" . JQ9 U 7 .   ? 21.65981  -14.03275 14.62287 1.000 70.97125  ? 1220 JQ9 A "C3'" 1 
HETATM 6386 C  "C2'" . JQ9 U 7 .   ? 21.83993  -12.71837 15.01116 1.000 69.96992  ? 1220 JQ9 A "C2'" 1 
HETATM 6387 O  "O3'" . JQ9 U 7 .   ? 22.54551  -14.77402 13.93567 1.000 67.75492  ? 1220 JQ9 A "O3'" 1 
HETATM 6388 C  "C9'" . JQ9 U 7 .   ? 23.64365  -14.11577 13.32001 1.000 67.90852  ? 1220 JQ9 A "C9'" 1 
HETATM 6389 H  H1    . JQ9 U 7 .   ? 20.61831  -3.95791  21.21087 1.000 73.01550  ? 1220 JQ9 A H1    1 
HETATM 6390 H  H2    . JQ9 U 7 .   ? 21.97239  -3.18300  21.11489 1.000 73.01550  ? 1220 JQ9 A H2    1 
HETATM 6391 H  H3    . JQ9 U 7 .   ? 20.63263  -2.39684  21.28871 1.000 73.01550  ? 1220 JQ9 A H3    1 
HETATM 6392 H  H4    . JQ9 U 7 .   ? 23.56493  -6.34993  15.71765 1.000 62.24422  ? 1220 JQ9 A H4    1 
HETATM 6393 H  H5    . JQ9 U 7 .   ? 24.05122  -4.93678  16.16949 1.000 62.24422  ? 1220 JQ9 A H5    1 
HETATM 6394 H  H6    . JQ9 U 7 .   ? 25.74726  -6.45340  16.77587 1.000 65.24157  ? 1220 JQ9 A H6    1 
HETATM 6395 H  H7    . JQ9 U 7 .   ? 25.08426  -5.97963  18.11186 1.000 65.24157  ? 1220 JQ9 A H7    1 
HETATM 6396 H  H8    . JQ9 U 7 .   ? 24.71498  -7.37480  17.50685 1.000 65.24157  ? 1220 JQ9 A H8    1 
HETATM 6397 H  H9    . JQ9 U 7 .   ? 18.30802  -7.35182  19.20174 1.000 59.90064  ? 1220 JQ9 A H9    1 
HETATM 6398 H  H10   . JQ9 U 7 .   ? 18.01743  -8.40574  18.06639 1.000 59.90064  ? 1220 JQ9 A H10   1 
HETATM 6399 H  H11   . JQ9 U 7 .   ? 18.79421  -8.84201  19.36659 1.000 59.90064  ? 1220 JQ9 A H11   1 
HETATM 6400 H  H12   . JQ9 U 7 .   ? 21.49271  -2.42369  18.96754 1.000 58.46162  ? 1220 JQ9 A H12   1 
HETATM 6401 H  H13   . JQ9 U 7 .   ? 19.98787  -2.81596  19.09802 1.000 58.46162  ? 1220 JQ9 A H13   1 
HETATM 6402 H  H14   . JQ9 U 7 .   ? 19.63649  -10.29259 17.37606 1.000 65.15477  ? 1220 JQ9 A H14   1 
HETATM 6403 H  H15   . JQ9 U 7 .   ? 21.85366  -10.25023 15.71285 1.000 69.48856  ? 1220 JQ9 A H15   1 
HETATM 6404 H  H16   . JQ9 U 7 .   ? 18.99541  -12.27487 16.52046 1.000 72.62201  ? 1220 JQ9 A H16   1 
HETATM 6405 H  H17   . JQ9 U 7 .   ? 18.68146  -14.43534 15.88321 1.000 74.78751  ? 1220 JQ9 A H17   1 
HETATM 6406 H  H18   . JQ9 U 7 .   ? 18.85550  -16.70638 15.58554 1.000 91.76954  ? 1220 JQ9 A H18   1 
HETATM 6407 H  H19   . JQ9 U 7 .   ? 18.43928  -16.25072 14.15405 1.000 91.76954  ? 1220 JQ9 A H19   1 
HETATM 6408 H  H20   . JQ9 U 7 .   ? 19.22226  -17.58424 14.35069 1.000 91.76954  ? 1220 JQ9 A H20   1 
HETATM 6409 H  H21   . JQ9 U 7 .   ? 22.62776  -12.27133 14.80054 1.000 84.00712  ? 1220 JQ9 A H21   1 
HETATM 6410 H  H22   . JQ9 U 7 .   ? 24.28116  -13.78452 13.97174 1.000 81.53343  ? 1220 JQ9 A H22   1 
HETATM 6411 H  H23   . JQ9 U 7 .   ? 24.13259  -14.70406 12.72356 1.000 81.53343  ? 1220 JQ9 A H23   1 
HETATM 6412 H  H24   . JQ9 U 7 .   ? 23.36092  -13.35297 12.79171 1.000 81.53343  ? 1220 JQ9 A H24   1 
HETATM 6413 O  O     . HOH V 8 .   ? 0.49231   62.52995  20.16080 1.000 115.87919 ? 1301 HOH A O     1 
HETATM 6414 O  O     . HOH V 8 .   ? 15.31330  -9.22443  18.59188 1.000 45.92446  ? 1302 HOH A O     1 
HETATM 6415 O  O     . HOH V 8 .   ? 20.31595  2.78604   26.58425 1.000 66.29068  ? 1303 HOH A O     1 
HETATM 6416 O  O     . HOH V 8 .   ? 32.91806  -13.08971 1.71423  1.000 85.23603  ? 1304 HOH A O     1 
HETATM 6417 O  O     . HOH V 8 .   ? 25.09235  7.85187   17.76346 1.000 54.56904  ? 1305 HOH A O     1 
HETATM 6418 O  O     . HOH V 8 .   ? 25.05972  13.28325  13.86284 1.000 57.65211  ? 1306 HOH A O     1 
HETATM 6419 O  O     . HOH V 8 .   ? 16.28053  -13.78362 21.53584 1.000 68.00001  ? 1307 HOH A O     1 
HETATM 6420 O  O     . HOH V 8 .   ? 27.85651  -2.46511  17.29265 1.000 45.48718  ? 1308 HOH A O     1 
HETATM 6421 O  O     . HOH V 8 .   ? 24.94179  -1.86099  16.18826 1.000 40.90268  ? 1309 HOH A O     1 
HETATM 6422 O  O     . HOH V 8 .   ? 19.60208  1.64541   22.84886 1.000 50.07341  ? 1310 HOH A O     1 
HETATM 6423 O  O     . HOH V 8 .   ? 25.30421  15.92880  14.65314 1.000 53.02468  ? 1311 HOH A O     1 
HETATM 6424 O  O     . HOH V 8 .   ? 22.15758  10.18136  14.64634 1.000 59.73456  ? 1312 HOH A O     1 
HETATM 6425 O  O     . HOH V 8 .   ? 28.26575  -2.76844  20.11766 1.000 45.73912  ? 1313 HOH A O     1 
HETATM 6426 O  O     . HOH V 8 .   ? 26.19890  12.51200  21.65423 1.000 49.82028  ? 1314 HOH A O     1 
HETATM 6427 O  O     . HOH V 8 .   ? 25.40324  -11.86365 16.95396 1.000 59.32156  ? 1315 HOH A O     1 
HETATM 6428 O  O     . HOH V 8 .   ? 19.31845  11.37666  13.42982 1.000 55.65586  ? 1316 HOH A O     1 
HETATM 6429 O  O     . HOH V 8 .   ? 16.52446  17.07351  19.58699 1.000 53.90086  ? 1317 HOH A O     1 
HETATM 6430 O  O     . HOH V 8 .   ? 16.29204  -0.50629  12.74636 1.000 50.21797  ? 1318 HOH A O     1 
HETATM 6431 O  O     . HOH V 8 .   ? 24.00345  11.00308  11.49949 1.000 51.64727  ? 1319 HOH A O     1 
HETATM 6432 O  O     . HOH V 8 .   ? 17.80004  -11.04108 33.09540 1.000 56.45195  ? 1320 HOH A O     1 
HETATM 6433 O  O     . HOH V 8 .   ? 26.74129  -18.60825 22.53381 1.000 66.45113  ? 1321 HOH A O     1 
HETATM 6434 O  O     . HOH V 8 .   ? 11.23152  -11.87269 16.51878 1.000 53.72556  ? 1322 HOH A O     1 
HETATM 6435 O  O     . HOH V 8 .   ? -7.88030  71.45816  26.73583 1.000 136.12068 ? 1323 HOH A O     1 
HETATM 6436 O  O     . HOH V 8 .   ? 18.38739  2.80592   20.65674 1.000 43.26433  ? 1324 HOH A O     1 
HETATM 6437 O  O     . HOH V 8 .   ? 19.45011  -9.31717  23.34774 1.000 63.73635  ? 1325 HOH A O     1 
HETATM 6438 O  O     . HOH V 8 .   ? 22.01212  -12.91723 18.34278 1.000 55.11226  ? 1326 HOH A O     1 
HETATM 6439 O  O     . HOH V 8 .   ? 21.10035  2.67434   24.71244 1.000 48.87892  ? 1327 HOH A O     1 
HETATM 6440 O  O     . HOH V 8 .   ? 15.18422  -3.31763  22.40752 1.000 44.49413  ? 1328 HOH A O     1 
HETATM 6441 O  O     . HOH V 8 .   ? 28.05792  -20.74653 22.75099 1.000 76.64271  ? 1329 HOH A O     1 
HETATM 6442 O  O     . HOH V 8 .   ? 24.25377  -9.33750  16.07281 1.000 48.43641  ? 1330 HOH A O     1 
HETATM 6443 O  O     . HOH V 8 .   ? 8.03047   53.14307  17.71253 1.000 122.61579 ? 1331 HOH A O     1 
HETATM 6444 O  O     . HOH V 8 .   ? 17.62848  -13.19391 27.18769 1.000 64.62758  ? 1332 HOH A O     1 
HETATM 6445 O  O     . HOH V 8 .   ? 25.45288  -7.89851  13.97657 1.000 53.64941  ? 1333 HOH A O     1 
HETATM 6446 O  O     . HOH V 8 .   ? 22.82454  5.97612   14.91955 1.000 50.65544  ? 1334 HOH A O     1 
HETATM 6447 O  O     . HOH V 8 .   ? 20.07863  -12.01558 33.74966 1.000 65.01290  ? 1335 HOH A O     1 
HETATM 6448 O  O     . HOH V 8 .   ? 26.32780  -3.93019  17.50440 1.000 63.44970  ? 1336 HOH A O     1 
HETATM 6449 O  O     . HOH V 8 .   ? 34.81991  -10.71294 34.44765 1.000 73.02858  ? 1337 HOH A O     1 
HETATM 6450 O  O     . HOH V 8 .   ? 14.89633  -12.21507 0.99429  1.000 75.86176  ? 1338 HOH A O     1 
HETATM 6451 O  O     . HOH V 8 .   ? 16.49648  -14.58238 1.71986  1.000 63.79210  ? 1339 HOH A O     1 
HETATM 6452 O  O     . HOH V 8 .   ? 30.94269  0.11868   33.81509 1.000 68.95621  ? 1340 HOH A O     1 
HETATM 6453 O  O     . HOH V 8 .   ? 35.09634  -11.05892 8.24215  1.000 91.76324  ? 1341 HOH A O     1 
HETATM 6454 O  O     . HOH V 8 .   ? 41.90795  -7.47417  8.80902  1.000 107.24408 ? 1342 HOH A O     1 
# 
