data_9FUG
# 
_entry.id   9FUG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FUG         pdb_00009fug 10.2210/pdb9fug/pdb 
WWPDB D_1292139581 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-29 ? 
2 'Structure model' 1 1 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FUG 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              anthony.green@manchester.ac.uk 
_pdbx_contact_author.name_first         Anthony 
_pdbx_contact_author.name_last          Green 
_pdbx_contact_author.name_mi            P 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0454-1798 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Roberts, G.R.' 1 0000-0002-0533-6385 
'Leys, D.'      2 0000-0003-4845-8443 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            639 
_citation.language                  ? 
_citation.page_first                375 
_citation.page_last                 381 
_citation.title                     'Engineered enzymes for enantioselective nucleophilic aromatic substitutions.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-025-08611-0 
_citation.pdbx_database_id_PubMed   39814071 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lister, T.M.'      1  ? 
primary 'Roberts, G.W.'     2  ? 
primary 'Hossack, E.J.'     3  ? 
primary 'Zhao, F.'          4  ? 
primary 'Burke, A.J.'       5  ? 
primary 'Johannissen, L.O.' 6  ? 
primary 'Hardy, F.J.'       7  ? 
primary 'Millman, A.A.V.'   8  ? 
primary 'Leys, D.'          9  ? 
primary 'Larrosa, I.'       10 ? 
primary 'Green, A.P.'       11 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'SNAr1.3 (K39A)'        27578.701 1   ? ? ? ? 
2 non-polymer syn 'DI(HYDROXYETHYL)ETHER' 106.120   1   ? ? ? ? 
3 non-polymer syn 2,4-dinitroiodobenzene  294.003   1   ? ? ? ? 
4 non-polymer syn 'CHLORIDE ION'          35.453    1   ? ? ? ? 
5 water       nat water                   18.015    201 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MIRAVFFDSLGTLISVEGAYKVRLKIMEEVLGDYPLNPATLLDEYEKLAREAFSNYAGKPYRPMRDILEEVMRKLAEKYG
FKYPENLREISLRMACRYGELYPEVVEVLKSLKGKYHVGDILQRDTEPATAFLDALGIKDLFDSITTSEEAGFFKPHPRI
FELALKKAGVKGEKAVYVGDNPVKDAGGSKNLGMTSILLDRKGEKREFWDKADFIVSDLREVIKIVDELNGQGSLEHHHH
HH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MIRAVFFDSLGTLISVEGAYKVRLKIMEEVLGDYPLNPATLLDEYEKLAREAFSNYAGKPYRPMRDILEEVMRKLAEKYG
FKYPENLREISLRMACRYGELYPEVVEVLKSLKGKYHVGDILQRDTEPATAFLDALGIKDLFDSITTSEEAGFFKPHPRI
FELALKKAGVKGEKAVYVGDNPVKDAGGSKNLGMTSILLDRKGEKREFWDKADFIVSDLREVIKIVDELNGQGSLEHHHH
HH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'DI(HYDROXYETHYL)ETHER' PEG   
3 2,4-dinitroiodobenzene  A1IGD 
4 'CHLORIDE ION'          CL    
5 water                   HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ILE n 
1 3   ARG n 
1 4   ALA n 
1 5   VAL n 
1 6   PHE n 
1 7   PHE n 
1 8   ASP n 
1 9   SER n 
1 10  LEU n 
1 11  GLY n 
1 12  THR n 
1 13  LEU n 
1 14  ILE n 
1 15  SER n 
1 16  VAL n 
1 17  GLU n 
1 18  GLY n 
1 19  ALA n 
1 20  TYR n 
1 21  LYS n 
1 22  VAL n 
1 23  ARG n 
1 24  LEU n 
1 25  LYS n 
1 26  ILE n 
1 27  MET n 
1 28  GLU n 
1 29  GLU n 
1 30  VAL n 
1 31  LEU n 
1 32  GLY n 
1 33  ASP n 
1 34  TYR n 
1 35  PRO n 
1 36  LEU n 
1 37  ASN n 
1 38  PRO n 
1 39  ALA n 
1 40  THR n 
1 41  LEU n 
1 42  LEU n 
1 43  ASP n 
1 44  GLU n 
1 45  TYR n 
1 46  GLU n 
1 47  LYS n 
1 48  LEU n 
1 49  ALA n 
1 50  ARG n 
1 51  GLU n 
1 52  ALA n 
1 53  PHE n 
1 54  SER n 
1 55  ASN n 
1 56  TYR n 
1 57  ALA n 
1 58  GLY n 
1 59  LYS n 
1 60  PRO n 
1 61  TYR n 
1 62  ARG n 
1 63  PRO n 
1 64  MET n 
1 65  ARG n 
1 66  ASP n 
1 67  ILE n 
1 68  LEU n 
1 69  GLU n 
1 70  GLU n 
1 71  VAL n 
1 72  MET n 
1 73  ARG n 
1 74  LYS n 
1 75  LEU n 
1 76  ALA n 
1 77  GLU n 
1 78  LYS n 
1 79  TYR n 
1 80  GLY n 
1 81  PHE n 
1 82  LYS n 
1 83  TYR n 
1 84  PRO n 
1 85  GLU n 
1 86  ASN n 
1 87  LEU n 
1 88  ARG n 
1 89  GLU n 
1 90  ILE n 
1 91  SER n 
1 92  LEU n 
1 93  ARG n 
1 94  MET n 
1 95  ALA n 
1 96  CYS n 
1 97  ARG n 
1 98  TYR n 
1 99  GLY n 
1 100 GLU n 
1 101 LEU n 
1 102 TYR n 
1 103 PRO n 
1 104 GLU n 
1 105 VAL n 
1 106 VAL n 
1 107 GLU n 
1 108 VAL n 
1 109 LEU n 
1 110 LYS n 
1 111 SER n 
1 112 LEU n 
1 113 LYS n 
1 114 GLY n 
1 115 LYS n 
1 116 TYR n 
1 117 HIS n 
1 118 VAL n 
1 119 GLY n 
1 120 ASP n 
1 121 ILE n 
1 122 LEU n 
1 123 GLN n 
1 124 ARG n 
1 125 ASP n 
1 126 THR n 
1 127 GLU n 
1 128 PRO n 
1 129 ALA n 
1 130 THR n 
1 131 ALA n 
1 132 PHE n 
1 133 LEU n 
1 134 ASP n 
1 135 ALA n 
1 136 LEU n 
1 137 GLY n 
1 138 ILE n 
1 139 LYS n 
1 140 ASP n 
1 141 LEU n 
1 142 PHE n 
1 143 ASP n 
1 144 SER n 
1 145 ILE n 
1 146 THR n 
1 147 THR n 
1 148 SER n 
1 149 GLU n 
1 150 GLU n 
1 151 ALA n 
1 152 GLY n 
1 153 PHE n 
1 154 PHE n 
1 155 LYS n 
1 156 PRO n 
1 157 HIS n 
1 158 PRO n 
1 159 ARG n 
1 160 ILE n 
1 161 PHE n 
1 162 GLU n 
1 163 LEU n 
1 164 ALA n 
1 165 LEU n 
1 166 LYS n 
1 167 LYS n 
1 168 ALA n 
1 169 GLY n 
1 170 VAL n 
1 171 LYS n 
1 172 GLY n 
1 173 GLU n 
1 174 LYS n 
1 175 ALA n 
1 176 VAL n 
1 177 TYR n 
1 178 VAL n 
1 179 GLY n 
1 180 ASP n 
1 181 ASN n 
1 182 PRO n 
1 183 VAL n 
1 184 LYS n 
1 185 ASP n 
1 186 ALA n 
1 187 GLY n 
1 188 GLY n 
1 189 SER n 
1 190 LYS n 
1 191 ASN n 
1 192 LEU n 
1 193 GLY n 
1 194 MET n 
1 195 THR n 
1 196 SER n 
1 197 ILE n 
1 198 LEU n 
1 199 LEU n 
1 200 ASP n 
1 201 ARG n 
1 202 LYS n 
1 203 GLY n 
1 204 GLU n 
1 205 LYS n 
1 206 ARG n 
1 207 GLU n 
1 208 PHE n 
1 209 TRP n 
1 210 ASP n 
1 211 LYS n 
1 212 ALA n 
1 213 ASP n 
1 214 PHE n 
1 215 ILE n 
1 216 VAL n 
1 217 SER n 
1 218 ASP n 
1 219 LEU n 
1 220 ARG n 
1 221 GLU n 
1 222 VAL n 
1 223 ILE n 
1 224 LYS n 
1 225 ILE n 
1 226 VAL n 
1 227 ASP n 
1 228 GLU n 
1 229 LEU n 
1 230 ASN n 
1 231 GLY n 
1 232 GLN n 
1 233 GLY n 
1 234 SER n 
1 235 LEU n 
1 236 GLU n 
1 237 HIS n 
1 238 HIS n 
1 239 HIS n 
1 240 HIS n 
1 241 HIS n 
1 242 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   242 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'synthetic construct' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     32630 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1IGD non-polymer         . 2,4-dinitroiodobenzene  1-iodanyl-2,4-dinitro-benzene 'C6 H3 I N2 O4'  294.003 
ALA   'L-peptide linking' y ALANINE                 ?                             'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                ?                             'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE              ?                             'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'         ?                             'C4 H7 N O4'     133.103 
CL    non-polymer         . 'CHLORIDE ION'          ?                             'Cl -1'          35.453  
CYS   'L-peptide linking' y CYSTEINE                ?                             'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE               ?                             'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'         ?                             'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                 ?                             'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE               ?                             'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                   ?                             'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE              ?                             'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                 ?                             'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                  ?                             'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE              ?                             'C5 H11 N O2 S'  149.211 
PEG   non-polymer         . 'DI(HYDROXYETHYL)ETHER' ?                             'C4 H10 O3'      106.120 
PHE   'L-peptide linking' y PHENYLALANINE           ?                             'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                 ?                             'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                  ?                             'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE               ?                             'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN              ?                             'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                ?                             'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                  ?                             'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   ILE 2   2   2   ILE ILE A . n 
A 1 3   ARG 3   3   3   ARG ARG A . n 
A 1 4   ALA 4   4   4   ALA ALA A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   PHE 6   6   6   PHE PHE A . n 
A 1 7   PHE 7   7   7   PHE PHE A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   SER 9   9   9   SER SER A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  THR 12  12  12  THR THR A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  ILE 14  14  14  ILE ILE A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  TYR 20  20  20  TYR TYR A . n 
A 1 21  LYS 21  21  21  LYS LYS A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ARG 23  23  23  ARG ARG A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  LYS 25  25  25  LYS LYS A . n 
A 1 26  ILE 26  26  26  ILE ILE A . n 
A 1 27  MET 27  27  27  MET MET A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  GLU 29  29  29  GLU GLU A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  ASN 37  37  37  ASN ASN A . n 
A 1 38  PRO 38  38  38  PRO PRO A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  ASP 43  43  43  ASP ASP A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  TYR 45  45  45  TYR TYR A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  LYS 47  47  47  LYS LYS A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  ARG 50  50  50  ARG ARG A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  PHE 53  53  53  PHE PHE A . n 
A 1 54  SER 54  54  54  SER SER A . n 
A 1 55  ASN 55  55  55  ASN ASN A . n 
A 1 56  TYR 56  56  56  TYR TYR A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  GLY 58  58  58  GLY GLY A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  TYR 61  61  61  TYR TYR A . n 
A 1 62  ARG 62  62  62  ARG ARG A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  MET 64  64  64  MET MET A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  MET 72  72  72  MET MET A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  LYS 74  74  74  LYS LYS A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  TYR 79  79  79  TYR TYR A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  LYS 82  82  82  LYS LYS A . n 
A 1 83  TYR 83  83  83  TYR TYR A . n 
A 1 84  PRO 84  84  84  PRO PRO A . n 
A 1 85  GLU 85  85  85  GLU GLU A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  GLU 89  89  89  GLU GLU A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  MET 94  94  94  MET MET A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  CYS 96  96  96  CYS CYS A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 TYR 102 102 102 TYR TYR A . n 
A 1 103 PRO 103 103 103 PRO PRO A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 VAL 108 108 108 VAL VAL A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 LYS 110 110 110 LYS LYS A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 LYS 113 113 113 LYS LYS A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 LYS 115 115 115 LYS LYS A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 HIS 117 117 117 HIS HIS A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 ARG 124 124 124 ARG ARG A . n 
A 1 125 ASP 125 125 125 ASP ASP A . n 
A 1 126 THR 126 126 126 THR THR A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 PRO 128 128 128 PRO PRO A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 PHE 132 132 132 PHE PHE A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ASP 134 134 134 ASP ASP A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 ILE 138 138 138 ILE ILE A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 ILE 145 145 145 ILE ILE A . n 
A 1 146 THR 146 146 146 THR THR A . n 
A 1 147 THR 147 147 147 THR THR A . n 
A 1 148 SER 148 148 148 SER SER A . n 
A 1 149 GLU 149 149 149 GLU GLU A . n 
A 1 150 GLU 150 150 150 GLU GLU A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 GLY 152 152 152 GLY GLY A . n 
A 1 153 PHE 153 153 153 PHE PHE A . n 
A 1 154 PHE 154 154 154 PHE PHE A . n 
A 1 155 LYS 155 155 155 LYS LYS A . n 
A 1 156 PRO 156 156 156 PRO PRO A . n 
A 1 157 HIS 157 157 157 HIS HIS A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 ARG 159 159 159 ARG ARG A . n 
A 1 160 ILE 160 160 160 ILE ILE A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 LYS 166 166 166 LYS LYS A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 GLY 169 169 169 GLY GLY A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 LYS 171 171 171 LYS LYS A . n 
A 1 172 GLY 172 172 172 GLY GLY A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 LYS 174 174 174 LYS LYS A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 TYR 177 177 177 TYR TYR A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 ASN 181 181 181 ASN ASN A . n 
A 1 182 PRO 182 182 182 PRO PRO A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 LYS 184 184 184 LYS LYS A . n 
A 1 185 ASP 185 185 185 ASP ASP A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 LYS 190 190 190 LYS LYS A . n 
A 1 191 ASN 191 191 191 ASN ASN A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 ARG 201 201 201 ARG ARG A . n 
A 1 202 LYS 202 202 202 LYS LYS A . n 
A 1 203 GLY 203 203 203 GLY GLY A . n 
A 1 204 GLU 204 204 204 GLU GLU A . n 
A 1 205 LYS 205 205 205 LYS LYS A . n 
A 1 206 ARG 206 206 206 ARG ARG A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 PHE 208 208 208 PHE PHE A . n 
A 1 209 TRP 209 209 209 TRP TRP A . n 
A 1 210 ASP 210 210 210 ASP ASP A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 ALA 212 212 212 ALA ALA A . n 
A 1 213 ASP 213 213 213 ASP ASP A . n 
A 1 214 PHE 214 214 214 PHE PHE A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 SER 217 217 217 SER SER A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 ARG 220 220 220 ARG ARG A . n 
A 1 221 GLU 221 221 221 GLU GLU A . n 
A 1 222 VAL 222 222 222 VAL VAL A . n 
A 1 223 ILE 223 223 223 ILE ILE A . n 
A 1 224 LYS 224 224 224 LYS LYS A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 ASP 227 227 227 ASP ASP A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 ASN 230 230 230 ASN ASN A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 GLN 232 232 ?   ?   ?   A . n 
A 1 233 GLY 233 233 ?   ?   ?   A . n 
A 1 234 SER 234 234 ?   ?   ?   A . n 
A 1 235 LEU 235 235 ?   ?   ?   A . n 
A 1 236 GLU 236 236 ?   ?   ?   A . n 
A 1 237 HIS 237 237 ?   ?   ?   A . n 
A 1 238 HIS 238 238 ?   ?   ?   A . n 
A 1 239 HIS 239 239 ?   ?   ?   A . n 
A 1 240 HIS 240 240 ?   ?   ?   A . n 
A 1 241 HIS 241 241 ?   ?   ?   A . n 
A 1 242 HIS 242 242 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1IGD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1IGD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 PEG   1   301 232 PEG   PEG A . 
C 3 A1IGD 1   302 233 A1IGD LIG A . 
D 4 CL    1   303 234 CL    CL  A . 
E 5 HOH   1   401 292 HOH   HOH A . 
E 5 HOH   2   402 391 HOH   HOH A . 
E 5 HOH   3   403 409 HOH   HOH A . 
E 5 HOH   4   404 388 HOH   HOH A . 
E 5 HOH   5   405 258 HOH   HOH A . 
E 5 HOH   6   406 336 HOH   HOH A . 
E 5 HOH   7   407 420 HOH   HOH A . 
E 5 HOH   8   408 387 HOH   HOH A . 
E 5 HOH   9   409 351 HOH   HOH A . 
E 5 HOH   10  410 281 HOH   HOH A . 
E 5 HOH   11  411 378 HOH   HOH A . 
E 5 HOH   12  412 355 HOH   HOH A . 
E 5 HOH   13  413 350 HOH   HOH A . 
E 5 HOH   14  414 287 HOH   HOH A . 
E 5 HOH   15  415 247 HOH   HOH A . 
E 5 HOH   16  416 408 HOH   HOH A . 
E 5 HOH   17  417 401 HOH   HOH A . 
E 5 HOH   18  418 295 HOH   HOH A . 
E 5 HOH   19  419 375 HOH   HOH A . 
E 5 HOH   20  420 271 HOH   HOH A . 
E 5 HOH   21  421 383 HOH   HOH A . 
E 5 HOH   22  422 313 HOH   HOH A . 
E 5 HOH   23  423 304 HOH   HOH A . 
E 5 HOH   24  424 357 HOH   HOH A . 
E 5 HOH   25  425 246 HOH   HOH A . 
E 5 HOH   26  426 312 HOH   HOH A . 
E 5 HOH   27  427 324 HOH   HOH A . 
E 5 HOH   28  428 291 HOH   HOH A . 
E 5 HOH   29  429 243 HOH   HOH A . 
E 5 HOH   30  430 266 HOH   HOH A . 
E 5 HOH   31  431 422 HOH   HOH A . 
E 5 HOH   32  432 241 HOH   HOH A . 
E 5 HOH   33  433 236 HOH   HOH A . 
E 5 HOH   34  434 264 HOH   HOH A . 
E 5 HOH   35  435 302 HOH   HOH A . 
E 5 HOH   36  436 237 HOH   HOH A . 
E 5 HOH   37  437 417 HOH   HOH A . 
E 5 HOH   38  438 305 HOH   HOH A . 
E 5 HOH   39  439 284 HOH   HOH A . 
E 5 HOH   40  440 262 HOH   HOH A . 
E 5 HOH   41  441 298 HOH   HOH A . 
E 5 HOH   42  442 317 HOH   HOH A . 
E 5 HOH   43  443 392 HOH   HOH A . 
E 5 HOH   44  444 333 HOH   HOH A . 
E 5 HOH   45  445 404 HOH   HOH A . 
E 5 HOH   46  446 294 HOH   HOH A . 
E 5 HOH   47  447 322 HOH   HOH A . 
E 5 HOH   48  448 251 HOH   HOH A . 
E 5 HOH   49  449 263 HOH   HOH A . 
E 5 HOH   50  450 238 HOH   HOH A . 
E 5 HOH   51  451 374 HOH   HOH A . 
E 5 HOH   52  452 270 HOH   HOH A . 
E 5 HOH   53  453 250 HOH   HOH A . 
E 5 HOH   54  454 278 HOH   HOH A . 
E 5 HOH   55  455 325 HOH   HOH A . 
E 5 HOH   56  456 386 HOH   HOH A . 
E 5 HOH   57  457 260 HOH   HOH A . 
E 5 HOH   58  458 403 HOH   HOH A . 
E 5 HOH   59  459 303 HOH   HOH A . 
E 5 HOH   60  460 280 HOH   HOH A . 
E 5 HOH   61  461 282 HOH   HOH A . 
E 5 HOH   62  462 242 HOH   HOH A . 
E 5 HOH   63  463 248 HOH   HOH A . 
E 5 HOH   64  464 240 HOH   HOH A . 
E 5 HOH   65  465 235 HOH   HOH A . 
E 5 HOH   66  466 353 HOH   HOH A . 
E 5 HOH   67  467 332 HOH   HOH A . 
E 5 HOH   68  468 289 HOH   HOH A . 
E 5 HOH   69  469 411 HOH   HOH A . 
E 5 HOH   70  470 349 HOH   HOH A . 
E 5 HOH   71  471 283 HOH   HOH A . 
E 5 HOH   72  472 265 HOH   HOH A . 
E 5 HOH   73  473 293 HOH   HOH A . 
E 5 HOH   74  474 352 HOH   HOH A . 
E 5 HOH   75  475 239 HOH   HOH A . 
E 5 HOH   76  476 290 HOH   HOH A . 
E 5 HOH   77  477 329 HOH   HOH A . 
E 5 HOH   78  478 244 HOH   HOH A . 
E 5 HOH   79  479 348 HOH   HOH A . 
E 5 HOH   80  480 330 HOH   HOH A . 
E 5 HOH   81  481 402 HOH   HOH A . 
E 5 HOH   82  482 256 HOH   HOH A . 
E 5 HOH   83  483 412 HOH   HOH A . 
E 5 HOH   84  484 356 HOH   HOH A . 
E 5 HOH   85  485 379 HOH   HOH A . 
E 5 HOH   86  486 328 HOH   HOH A . 
E 5 HOH   87  487 297 HOH   HOH A . 
E 5 HOH   88  488 277 HOH   HOH A . 
E 5 HOH   89  489 261 HOH   HOH A . 
E 5 HOH   90  490 255 HOH   HOH A . 
E 5 HOH   91  491 309 HOH   HOH A . 
E 5 HOH   92  492 300 HOH   HOH A . 
E 5 HOH   93  493 382 HOH   HOH A . 
E 5 HOH   94  494 424 HOH   HOH A . 
E 5 HOH   95  495 245 HOH   HOH A . 
E 5 HOH   96  496 428 HOH   HOH A . 
E 5 HOH   97  497 310 HOH   HOH A . 
E 5 HOH   98  498 275 HOH   HOH A . 
E 5 HOH   99  499 368 HOH   HOH A . 
E 5 HOH   100 500 414 HOH   HOH A . 
E 5 HOH   101 501 399 HOH   HOH A . 
E 5 HOH   102 502 360 HOH   HOH A . 
E 5 HOH   103 503 274 HOH   HOH A . 
E 5 HOH   104 504 307 HOH   HOH A . 
E 5 HOH   105 505 254 HOH   HOH A . 
E 5 HOH   106 506 259 HOH   HOH A . 
E 5 HOH   107 507 279 HOH   HOH A . 
E 5 HOH   108 508 367 HOH   HOH A . 
E 5 HOH   109 509 257 HOH   HOH A . 
E 5 HOH   110 510 429 HOH   HOH A . 
E 5 HOH   111 511 344 HOH   HOH A . 
E 5 HOH   112 512 249 HOH   HOH A . 
E 5 HOH   113 513 276 HOH   HOH A . 
E 5 HOH   114 514 343 HOH   HOH A . 
E 5 HOH   115 515 398 HOH   HOH A . 
E 5 HOH   116 516 327 HOH   HOH A . 
E 5 HOH   117 517 363 HOH   HOH A . 
E 5 HOH   118 518 311 HOH   HOH A . 
E 5 HOH   119 519 272 HOH   HOH A . 
E 5 HOH   120 520 418 HOH   HOH A . 
E 5 HOH   121 521 252 HOH   HOH A . 
E 5 HOH   122 522 331 HOH   HOH A . 
E 5 HOH   123 523 338 HOH   HOH A . 
E 5 HOH   124 524 319 HOH   HOH A . 
E 5 HOH   125 525 359 HOH   HOH A . 
E 5 HOH   126 526 308 HOH   HOH A . 
E 5 HOH   127 527 301 HOH   HOH A . 
E 5 HOH   128 528 372 HOH   HOH A . 
E 5 HOH   129 529 286 HOH   HOH A . 
E 5 HOH   130 530 253 HOH   HOH A . 
E 5 HOH   131 531 395 HOH   HOH A . 
E 5 HOH   132 532 316 HOH   HOH A . 
E 5 HOH   133 533 369 HOH   HOH A . 
E 5 HOH   134 534 269 HOH   HOH A . 
E 5 HOH   135 535 405 HOH   HOH A . 
E 5 HOH   136 536 376 HOH   HOH A . 
E 5 HOH   137 537 334 HOH   HOH A . 
E 5 HOH   138 538 384 HOH   HOH A . 
E 5 HOH   139 539 419 HOH   HOH A . 
E 5 HOH   140 540 288 HOH   HOH A . 
E 5 HOH   141 541 306 HOH   HOH A . 
E 5 HOH   142 542 347 HOH   HOH A . 
E 5 HOH   143 543 326 HOH   HOH A . 
E 5 HOH   144 544 273 HOH   HOH A . 
E 5 HOH   145 545 366 HOH   HOH A . 
E 5 HOH   146 546 321 HOH   HOH A . 
E 5 HOH   147 547 393 HOH   HOH A . 
E 5 HOH   148 548 296 HOH   HOH A . 
E 5 HOH   149 549 397 HOH   HOH A . 
E 5 HOH   150 550 423 HOH   HOH A . 
E 5 HOH   151 551 389 HOH   HOH A . 
E 5 HOH   152 552 381 HOH   HOH A . 
E 5 HOH   153 553 371 HOH   HOH A . 
E 5 HOH   154 554 427 HOH   HOH A . 
E 5 HOH   155 555 299 HOH   HOH A . 
E 5 HOH   156 556 323 HOH   HOH A . 
E 5 HOH   157 557 400 HOH   HOH A . 
E 5 HOH   158 558 396 HOH   HOH A . 
E 5 HOH   159 559 394 HOH   HOH A . 
E 5 HOH   160 560 421 HOH   HOH A . 
E 5 HOH   161 561 434 HOH   HOH A . 
E 5 HOH   162 562 415 HOH   HOH A . 
E 5 HOH   163 563 354 HOH   HOH A . 
E 5 HOH   164 564 425 HOH   HOH A . 
E 5 HOH   165 565 433 HOH   HOH A . 
E 5 HOH   166 566 390 HOH   HOH A . 
E 5 HOH   167 567 342 HOH   HOH A . 
E 5 HOH   168 568 361 HOH   HOH A . 
E 5 HOH   169 569 377 HOH   HOH A . 
E 5 HOH   170 570 358 HOH   HOH A . 
E 5 HOH   171 571 337 HOH   HOH A . 
E 5 HOH   172 572 373 HOH   HOH A . 
E 5 HOH   173 573 385 HOH   HOH A . 
E 5 HOH   174 574 339 HOH   HOH A . 
E 5 HOH   175 575 314 HOH   HOH A . 
E 5 HOH   176 576 268 HOH   HOH A . 
E 5 HOH   177 577 318 HOH   HOH A . 
E 5 HOH   178 578 370 HOH   HOH A . 
E 5 HOH   179 579 380 HOH   HOH A . 
E 5 HOH   180 580 430 HOH   HOH A . 
E 5 HOH   181 581 406 HOH   HOH A . 
E 5 HOH   182 582 315 HOH   HOH A . 
E 5 HOH   183 583 364 HOH   HOH A . 
E 5 HOH   184 584 346 HOH   HOH A . 
E 5 HOH   185 585 285 HOH   HOH A . 
E 5 HOH   186 586 413 HOH   HOH A . 
E 5 HOH   187 587 340 HOH   HOH A . 
E 5 HOH   188 588 341 HOH   HOH A . 
E 5 HOH   189 589 431 HOH   HOH A . 
E 5 HOH   190 590 432 HOH   HOH A . 
E 5 HOH   191 591 435 HOH   HOH A . 
E 5 HOH   192 592 320 HOH   HOH A . 
E 5 HOH   193 593 365 HOH   HOH A . 
E 5 HOH   194 594 267 HOH   HOH A . 
E 5 HOH   195 595 345 HOH   HOH A . 
E 5 HOH   196 596 407 HOH   HOH A . 
E 5 HOH   197 597 335 HOH   HOH A . 
E 5 HOH   198 598 416 HOH   HOH A . 
E 5 HOH   199 599 362 HOH   HOH A . 
E 5 HOH   200 600 410 HOH   HOH A . 
E 5 HOH   201 601 426 HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A ASN 181 ? CG  ? A ASN 181 CG  
2 1 Y 1 A ASN 181 ? OD1 ? A ASN 181 OD1 
3 1 Y 1 A ASN 181 ? ND2 ? A ASN 181 ND2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.21_5207 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FUG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     70.364 
_cell.length_a_esd                 ? 
_cell.length_b                     70.364 
_cell.length_b_esd                 ? 
_cell.length_c                     119.519 
_cell.length_c_esd                 ? 
_cell.volume                       512474.577 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FUG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            
;P 31 2"
;
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FUG 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.10 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.28 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M sodium citrate tribasic dihydrate, 20% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-04-27 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9763 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9763 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          35.48 
_reflns.entry_id                                       9FUG 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.71 
_reflns.d_resolution_low                               54.29 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     37752 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                20.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.0 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.71 
_reflns_shell.d_res_low                                     1.75 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1857 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.3 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               45.28 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FUG 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.71 
_refine.ls_d_res_low                             42.67 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     37485 
_refine.ls_number_reflns_R_free                  1959 
_refine.ls_number_reflns_R_work                  35526 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.41 
_refine.ls_percent_reflns_R_free                 5.23 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2058 
_refine.ls_R_factor_R_free                       0.2430 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2038 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.0756 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2693 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.71 
_refine_hist.d_res_low                        42.67 
_refine_hist.number_atoms_solvent             201 
_refine_hist.number_atoms_total               2064 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1842 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         21 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0058  ? 2040 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6222  ? 2762 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0455  ? 294  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0051  ? 359  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.6252 ? 810  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.71 1.75  . . 129 2330 92.30  . . . . 0.3958 . . . . . . . . . . . 0.4054 
'X-RAY DIFFRACTION' 1.75 1.80  . . 143 2506 99.81  . . . . 0.3766 . . . . . . . . . . . 0.3839 
'X-RAY DIFFRACTION' 1.80 1.85  . . 119 2531 99.96  . . . . 0.3805 . . . . . . . . . . . 0.3672 
'X-RAY DIFFRACTION' 1.85 1.91  . . 160 2467 99.81  . . . . 0.3225 . . . . . . . . . . . 0.3746 
'X-RAY DIFFRACTION' 1.91 1.98  . . 144 2522 100.00 . . . . 0.2738 . . . . . . . . . . . 0.3101 
'X-RAY DIFFRACTION' 1.98 2.06  . . 128 2554 99.96  . . . . 0.2330 . . . . . . . . . . . 0.3122 
'X-RAY DIFFRACTION' 2.06 2.15  . . 145 2487 100.00 . . . . 0.2267 . . . . . . . . . . . 0.2467 
'X-RAY DIFFRACTION' 2.15 2.27  . . 157 2542 100.00 . . . . 0.2107 . . . . . . . . . . . 0.2544 
'X-RAY DIFFRACTION' 2.27 2.41  . . 125 2537 99.96  . . . . 0.2278 . . . . . . . . . . . 0.3008 
'X-RAY DIFFRACTION' 2.41 2.60  . . 125 2585 100.00 . . . . 0.1973 . . . . . . . . . . . 0.2575 
'X-RAY DIFFRACTION' 2.60 2.86  . . 124 2564 99.96  . . . . 0.2230 . . . . . . . . . . . 0.2366 
'X-RAY DIFFRACTION' 2.86 3.27  . . 157 2563 100.00 . . . . 0.2060 . . . . . . . . . . . 0.2182 
'X-RAY DIFFRACTION' 3.27 4.12  . . 149 2614 100.00 . . . . 0.1730 . . . . . . . . . . . 0.2336 
'X-RAY DIFFRACTION' 4.12 42.67 . . 154 2724 99.93  . . . . 0.1692 . . . . . . . . . . . 0.2052 
# 
_struct.entry_id                     9FUG 
_struct.title                        'Crystal structure of SNAr1.3 (K39A) in complex with 2,4-dinitroiodobenzene' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FUG 
_struct_keywords.text            'SNArase, BIOSYNTHETIC PROTEIN' 
_struct_keywords.pdbx_keywords   'BIOSYNTHETIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9FUG 
_struct_ref.pdbx_db_accession          9FUG 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9FUG 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 242 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9FUG 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  242 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       242 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 540   ? 
1 MORE         -8    ? 
1 'SSA (A^2)'  11190 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   homology 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 8   ? LEU A 13  ? ASP A 8   LEU A 13  1 ? 6  
HELX_P HELX_P2  AA2 SER A 15  ? GLY A 32  ? SER A 15  GLY A 32  1 ? 18 
HELX_P HELX_P3  AA3 ASN A 37  ? ALA A 57  ? ASN A 37  ALA A 57  1 ? 21 
HELX_P HELX_P4  AA4 PRO A 63  ? GLY A 80  ? PRO A 63  GLY A 80  1 ? 18 
HELX_P HELX_P5  AA5 ASN A 86  ? GLY A 99  ? ASN A 86  GLY A 99  1 ? 14 
HELX_P HELX_P6  AA6 GLU A 104 ? GLY A 114 ? GLU A 104 GLY A 114 1 ? 11 
HELX_P HELX_P7  AA7 ASP A 125 ? LEU A 136 ? ASP A 125 LEU A 136 1 ? 12 
HELX_P HELX_P8  AA8 ILE A 138 ? PHE A 142 ? ILE A 138 PHE A 142 5 ? 5  
HELX_P HELX_P9  AA9 SER A 148 ? GLY A 152 ? SER A 148 GLY A 152 1 ? 5  
HELX_P HELX_P10 AB1 PRO A 158 ? GLY A 169 ? PRO A 158 GLY A 169 1 ? 12 
HELX_P HELX_P11 AB2 LYS A 171 ? GLU A 173 ? LYS A 171 GLU A 173 5 ? 3  
HELX_P HELX_P12 AB3 ASN A 181 ? LYS A 190 ? ASN A 181 LYS A 190 1 ? 10 
HELX_P HELX_P13 AB4 ASN A 191 ? GLY A 193 ? ASN A 191 GLY A 193 5 ? 3  
HELX_P HELX_P14 AB5 LYS A 205 ? ALA A 212 ? LYS A 205 ALA A 212 5 ? 8  
HELX_P HELX_P15 AB6 ARG A 220 ? ASN A 230 ? ARG A 220 ASN A 230 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LYS 
_struct_mon_prot_cis.label_seq_id           155 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LYS 
_struct_mon_prot_cis.auth_seq_id            155 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    156 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     156 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       3.24 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   6 
_struct_sheet.details          ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA1 4 5 ? parallel 
AA1 5 6 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 144 ? THR A 147 ? SER A 144 THR A 147 
AA1 2 HIS A 117 ? LEU A 122 ? HIS A 117 LEU A 122 
AA1 3 ALA A 4   ? PHE A 7   ? ALA A 4   PHE A 7   
AA1 4 ALA A 175 ? GLY A 179 ? ALA A 175 GLY A 179 
AA1 5 THR A 195 ? LEU A 199 ? THR A 195 LEU A 199 
AA1 6 PHE A 214 ? VAL A 216 ? PHE A 214 VAL A 216 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O THR A 146 ? O THR A 146 N LEU A 122 ? N LEU A 122 
AA1 2 3 O HIS A 117 ? O HIS A 117 N VAL A 5   ? N VAL A 5   
AA1 3 4 N PHE A 6   ? N PHE A 6   O VAL A 178 ? O VAL A 178 
AA1 4 5 N TYR A 177 ? N TYR A 177 O ILE A 197 ? O ILE A 197 
AA1 5 6 N LEU A 198 ? N LEU A 198 O PHE A 214 ? O PHE A 214 
# 
_pdbx_entry_details.entry_id                   9FUG 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OE1 A GLU 51  ? ? O A HOH 401 ? ? 1.83 
2 1 O   A HOH 456 ? ? O A HOH 578 ? ? 2.07 
3 1 O   A HOH 421 ? ? O A HOH 473 ? ? 2.11 
4 1 O   A HOH 442 ? ? O A HOH 551 ? ? 2.12 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     600 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   E 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+1/3   
3 -x+y,-x,z+2/3  
4 x-y,-y,-z+2/3  
5 -x,-x+y,-z+1/3 
6 y,x,-z         
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       601 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.16 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLN 232 ? A GLN 232 
2  1 Y 1 A GLY 233 ? A GLY 233 
3  1 Y 1 A SER 234 ? A SER 234 
4  1 Y 1 A LEU 235 ? A LEU 235 
5  1 Y 1 A GLU 236 ? A GLU 236 
6  1 Y 1 A HIS 237 ? A HIS 237 
7  1 Y 1 A HIS 238 ? A HIS 238 
8  1 Y 1 A HIS 239 ? A HIS 239 
9  1 Y 1 A HIS 240 ? A HIS 240 
10 1 Y 1 A HIS 241 ? A HIS 241 
11 1 Y 1 A HIS 242 ? A HIS 242 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1IGD C10  C  Y N 1   
A1IGD C02  C  Y N 2   
A1IGD C03  C  Y N 3   
A1IGD C04  C  Y N 4   
A1IGD C05  C  Y N 5   
A1IGD C09  C  Y N 6   
A1IGD I01  I  N N 7   
A1IGD N06  N  N N 8   
A1IGD N11  N  N N 9   
A1IGD O07  O  N N 10  
A1IGD O08  O  N N 11  
A1IGD O12  O  N N 12  
A1IGD O13  O  N N 13  
A1IGD H031 H  N N 14  
A1IGD H041 H  N N 15  
A1IGD H091 H  N N 16  
ALA   N    N  N N 17  
ALA   CA   C  N S 18  
ALA   C    C  N N 19  
ALA   O    O  N N 20  
ALA   CB   C  N N 21  
ALA   OXT  O  N N 22  
ALA   H    H  N N 23  
ALA   H2   H  N N 24  
ALA   HA   H  N N 25  
ALA   HB1  H  N N 26  
ALA   HB2  H  N N 27  
ALA   HB3  H  N N 28  
ALA   HXT  H  N N 29  
ARG   N    N  N N 30  
ARG   CA   C  N S 31  
ARG   C    C  N N 32  
ARG   O    O  N N 33  
ARG   CB   C  N N 34  
ARG   CG   C  N N 35  
ARG   CD   C  N N 36  
ARG   NE   N  N N 37  
ARG   CZ   C  N N 38  
ARG   NH1  N  N N 39  
ARG   NH2  N  N N 40  
ARG   OXT  O  N N 41  
ARG   H    H  N N 42  
ARG   H2   H  N N 43  
ARG   HA   H  N N 44  
ARG   HB2  H  N N 45  
ARG   HB3  H  N N 46  
ARG   HG2  H  N N 47  
ARG   HG3  H  N N 48  
ARG   HD2  H  N N 49  
ARG   HD3  H  N N 50  
ARG   HE   H  N N 51  
ARG   HH11 H  N N 52  
ARG   HH12 H  N N 53  
ARG   HH21 H  N N 54  
ARG   HH22 H  N N 55  
ARG   HXT  H  N N 56  
ASN   N    N  N N 57  
ASN   CA   C  N S 58  
ASN   C    C  N N 59  
ASN   O    O  N N 60  
ASN   CB   C  N N 61  
ASN   CG   C  N N 62  
ASN   OD1  O  N N 63  
ASN   ND2  N  N N 64  
ASN   OXT  O  N N 65  
ASN   H    H  N N 66  
ASN   H2   H  N N 67  
ASN   HA   H  N N 68  
ASN   HB2  H  N N 69  
ASN   HB3  H  N N 70  
ASN   HD21 H  N N 71  
ASN   HD22 H  N N 72  
ASN   HXT  H  N N 73  
ASP   N    N  N N 74  
ASP   CA   C  N S 75  
ASP   C    C  N N 76  
ASP   O    O  N N 77  
ASP   CB   C  N N 78  
ASP   CG   C  N N 79  
ASP   OD1  O  N N 80  
ASP   OD2  O  N N 81  
ASP   OXT  O  N N 82  
ASP   H    H  N N 83  
ASP   H2   H  N N 84  
ASP   HA   H  N N 85  
ASP   HB2  H  N N 86  
ASP   HB3  H  N N 87  
ASP   HD2  H  N N 88  
ASP   HXT  H  N N 89  
CL    CL   CL N N 90  
CYS   N    N  N N 91  
CYS   CA   C  N R 92  
CYS   C    C  N N 93  
CYS   O    O  N N 94  
CYS   CB   C  N N 95  
CYS   SG   S  N N 96  
CYS   OXT  O  N N 97  
CYS   H    H  N N 98  
CYS   H2   H  N N 99  
CYS   HA   H  N N 100 
CYS   HB2  H  N N 101 
CYS   HB3  H  N N 102 
CYS   HG   H  N N 103 
CYS   HXT  H  N N 104 
GLN   N    N  N N 105 
GLN   CA   C  N S 106 
GLN   C    C  N N 107 
GLN   O    O  N N 108 
GLN   CB   C  N N 109 
GLN   CG   C  N N 110 
GLN   CD   C  N N 111 
GLN   OE1  O  N N 112 
GLN   NE2  N  N N 113 
GLN   OXT  O  N N 114 
GLN   H    H  N N 115 
GLN   H2   H  N N 116 
GLN   HA   H  N N 117 
GLN   HB2  H  N N 118 
GLN   HB3  H  N N 119 
GLN   HG2  H  N N 120 
GLN   HG3  H  N N 121 
GLN   HE21 H  N N 122 
GLN   HE22 H  N N 123 
GLN   HXT  H  N N 124 
GLU   N    N  N N 125 
GLU   CA   C  N S 126 
GLU   C    C  N N 127 
GLU   O    O  N N 128 
GLU   CB   C  N N 129 
GLU   CG   C  N N 130 
GLU   CD   C  N N 131 
GLU   OE1  O  N N 132 
GLU   OE2  O  N N 133 
GLU   OXT  O  N N 134 
GLU   H    H  N N 135 
GLU   H2   H  N N 136 
GLU   HA   H  N N 137 
GLU   HB2  H  N N 138 
GLU   HB3  H  N N 139 
GLU   HG2  H  N N 140 
GLU   HG3  H  N N 141 
GLU   HE2  H  N N 142 
GLU   HXT  H  N N 143 
GLY   N    N  N N 144 
GLY   CA   C  N N 145 
GLY   C    C  N N 146 
GLY   O    O  N N 147 
GLY   OXT  O  N N 148 
GLY   H    H  N N 149 
GLY   H2   H  N N 150 
GLY   HA2  H  N N 151 
GLY   HA3  H  N N 152 
GLY   HXT  H  N N 153 
HIS   N    N  N N 154 
HIS   CA   C  N S 155 
HIS   C    C  N N 156 
HIS   O    O  N N 157 
HIS   CB   C  N N 158 
HIS   CG   C  Y N 159 
HIS   ND1  N  Y N 160 
HIS   CD2  C  Y N 161 
HIS   CE1  C  Y N 162 
HIS   NE2  N  Y N 163 
HIS   OXT  O  N N 164 
HIS   H    H  N N 165 
HIS   H2   H  N N 166 
HIS   HA   H  N N 167 
HIS   HB2  H  N N 168 
HIS   HB3  H  N N 169 
HIS   HD1  H  N N 170 
HIS   HD2  H  N N 171 
HIS   HE1  H  N N 172 
HIS   HE2  H  N N 173 
HIS   HXT  H  N N 174 
HOH   O    O  N N 175 
HOH   H1   H  N N 176 
HOH   H2   H  N N 177 
ILE   N    N  N N 178 
ILE   CA   C  N S 179 
ILE   C    C  N N 180 
ILE   O    O  N N 181 
ILE   CB   C  N S 182 
ILE   CG1  C  N N 183 
ILE   CG2  C  N N 184 
ILE   CD1  C  N N 185 
ILE   OXT  O  N N 186 
ILE   H    H  N N 187 
ILE   H2   H  N N 188 
ILE   HA   H  N N 189 
ILE   HB   H  N N 190 
ILE   HG12 H  N N 191 
ILE   HG13 H  N N 192 
ILE   HG21 H  N N 193 
ILE   HG22 H  N N 194 
ILE   HG23 H  N N 195 
ILE   HD11 H  N N 196 
ILE   HD12 H  N N 197 
ILE   HD13 H  N N 198 
ILE   HXT  H  N N 199 
LEU   N    N  N N 200 
LEU   CA   C  N S 201 
LEU   C    C  N N 202 
LEU   O    O  N N 203 
LEU   CB   C  N N 204 
LEU   CG   C  N N 205 
LEU   CD1  C  N N 206 
LEU   CD2  C  N N 207 
LEU   OXT  O  N N 208 
LEU   H    H  N N 209 
LEU   H2   H  N N 210 
LEU   HA   H  N N 211 
LEU   HB2  H  N N 212 
LEU   HB3  H  N N 213 
LEU   HG   H  N N 214 
LEU   HD11 H  N N 215 
LEU   HD12 H  N N 216 
LEU   HD13 H  N N 217 
LEU   HD21 H  N N 218 
LEU   HD22 H  N N 219 
LEU   HD23 H  N N 220 
LEU   HXT  H  N N 221 
LYS   N    N  N N 222 
LYS   CA   C  N S 223 
LYS   C    C  N N 224 
LYS   O    O  N N 225 
LYS   CB   C  N N 226 
LYS   CG   C  N N 227 
LYS   CD   C  N N 228 
LYS   CE   C  N N 229 
LYS   NZ   N  N N 230 
LYS   OXT  O  N N 231 
LYS   H    H  N N 232 
LYS   H2   H  N N 233 
LYS   HA   H  N N 234 
LYS   HB2  H  N N 235 
LYS   HB3  H  N N 236 
LYS   HG2  H  N N 237 
LYS   HG3  H  N N 238 
LYS   HD2  H  N N 239 
LYS   HD3  H  N N 240 
LYS   HE2  H  N N 241 
LYS   HE3  H  N N 242 
LYS   HZ1  H  N N 243 
LYS   HZ2  H  N N 244 
LYS   HZ3  H  N N 245 
LYS   HXT  H  N N 246 
MET   N    N  N N 247 
MET   CA   C  N S 248 
MET   C    C  N N 249 
MET   O    O  N N 250 
MET   CB   C  N N 251 
MET   CG   C  N N 252 
MET   SD   S  N N 253 
MET   CE   C  N N 254 
MET   OXT  O  N N 255 
MET   H    H  N N 256 
MET   H2   H  N N 257 
MET   HA   H  N N 258 
MET   HB2  H  N N 259 
MET   HB3  H  N N 260 
MET   HG2  H  N N 261 
MET   HG3  H  N N 262 
MET   HE1  H  N N 263 
MET   HE2  H  N N 264 
MET   HE3  H  N N 265 
MET   HXT  H  N N 266 
PEG   C1   C  N N 267 
PEG   O1   O  N N 268 
PEG   C2   C  N N 269 
PEG   O2   O  N N 270 
PEG   C3   C  N N 271 
PEG   C4   C  N N 272 
PEG   O4   O  N N 273 
PEG   H11  H  N N 274 
PEG   H12  H  N N 275 
PEG   HO1  H  N N 276 
PEG   H21  H  N N 277 
PEG   H22  H  N N 278 
PEG   H31  H  N N 279 
PEG   H32  H  N N 280 
PEG   H41  H  N N 281 
PEG   H42  H  N N 282 
PEG   HO4  H  N N 283 
PHE   N    N  N N 284 
PHE   CA   C  N S 285 
PHE   C    C  N N 286 
PHE   O    O  N N 287 
PHE   CB   C  N N 288 
PHE   CG   C  Y N 289 
PHE   CD1  C  Y N 290 
PHE   CD2  C  Y N 291 
PHE   CE1  C  Y N 292 
PHE   CE2  C  Y N 293 
PHE   CZ   C  Y N 294 
PHE   OXT  O  N N 295 
PHE   H    H  N N 296 
PHE   H2   H  N N 297 
PHE   HA   H  N N 298 
PHE   HB2  H  N N 299 
PHE   HB3  H  N N 300 
PHE   HD1  H  N N 301 
PHE   HD2  H  N N 302 
PHE   HE1  H  N N 303 
PHE   HE2  H  N N 304 
PHE   HZ   H  N N 305 
PHE   HXT  H  N N 306 
PRO   N    N  N N 307 
PRO   CA   C  N S 308 
PRO   C    C  N N 309 
PRO   O    O  N N 310 
PRO   CB   C  N N 311 
PRO   CG   C  N N 312 
PRO   CD   C  N N 313 
PRO   OXT  O  N N 314 
PRO   H    H  N N 315 
PRO   HA   H  N N 316 
PRO   HB2  H  N N 317 
PRO   HB3  H  N N 318 
PRO   HG2  H  N N 319 
PRO   HG3  H  N N 320 
PRO   HD2  H  N N 321 
PRO   HD3  H  N N 322 
PRO   HXT  H  N N 323 
SER   N    N  N N 324 
SER   CA   C  N S 325 
SER   C    C  N N 326 
SER   O    O  N N 327 
SER   CB   C  N N 328 
SER   OG   O  N N 329 
SER   OXT  O  N N 330 
SER   H    H  N N 331 
SER   H2   H  N N 332 
SER   HA   H  N N 333 
SER   HB2  H  N N 334 
SER   HB3  H  N N 335 
SER   HG   H  N N 336 
SER   HXT  H  N N 337 
THR   N    N  N N 338 
THR   CA   C  N S 339 
THR   C    C  N N 340 
THR   O    O  N N 341 
THR   CB   C  N R 342 
THR   OG1  O  N N 343 
THR   CG2  C  N N 344 
THR   OXT  O  N N 345 
THR   H    H  N N 346 
THR   H2   H  N N 347 
THR   HA   H  N N 348 
THR   HB   H  N N 349 
THR   HG1  H  N N 350 
THR   HG21 H  N N 351 
THR   HG22 H  N N 352 
THR   HG23 H  N N 353 
THR   HXT  H  N N 354 
TRP   N    N  N N 355 
TRP   CA   C  N S 356 
TRP   C    C  N N 357 
TRP   O    O  N N 358 
TRP   CB   C  N N 359 
TRP   CG   C  Y N 360 
TRP   CD1  C  Y N 361 
TRP   CD2  C  Y N 362 
TRP   NE1  N  Y N 363 
TRP   CE2  C  Y N 364 
TRP   CE3  C  Y N 365 
TRP   CZ2  C  Y N 366 
TRP   CZ3  C  Y N 367 
TRP   CH2  C  Y N 368 
TRP   OXT  O  N N 369 
TRP   H    H  N N 370 
TRP   H2   H  N N 371 
TRP   HA   H  N N 372 
TRP   HB2  H  N N 373 
TRP   HB3  H  N N 374 
TRP   HD1  H  N N 375 
TRP   HE1  H  N N 376 
TRP   HE3  H  N N 377 
TRP   HZ2  H  N N 378 
TRP   HZ3  H  N N 379 
TRP   HH2  H  N N 380 
TRP   HXT  H  N N 381 
TYR   N    N  N N 382 
TYR   CA   C  N S 383 
TYR   C    C  N N 384 
TYR   O    O  N N 385 
TYR   CB   C  N N 386 
TYR   CG   C  Y N 387 
TYR   CD1  C  Y N 388 
TYR   CD2  C  Y N 389 
TYR   CE1  C  Y N 390 
TYR   CE2  C  Y N 391 
TYR   CZ   C  Y N 392 
TYR   OH   O  N N 393 
TYR   OXT  O  N N 394 
TYR   H    H  N N 395 
TYR   H2   H  N N 396 
TYR   HA   H  N N 397 
TYR   HB2  H  N N 398 
TYR   HB3  H  N N 399 
TYR   HD1  H  N N 400 
TYR   HD2  H  N N 401 
TYR   HE1  H  N N 402 
TYR   HE2  H  N N 403 
TYR   HH   H  N N 404 
TYR   HXT  H  N N 405 
VAL   N    N  N N 406 
VAL   CA   C  N S 407 
VAL   C    C  N N 408 
VAL   O    O  N N 409 
VAL   CB   C  N N 410 
VAL   CG1  C  N N 411 
VAL   CG2  C  N N 412 
VAL   OXT  O  N N 413 
VAL   H    H  N N 414 
VAL   H2   H  N N 415 
VAL   HA   H  N N 416 
VAL   HB   H  N N 417 
VAL   HG11 H  N N 418 
VAL   HG12 H  N N 419 
VAL   HG13 H  N N 420 
VAL   HG21 H  N N 421 
VAL   HG22 H  N N 422 
VAL   HG23 H  N N 423 
VAL   HXT  H  N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1IGD C02 I01  sing N N 1   
A1IGD C03 C02  doub Y N 2   
A1IGD C04 C03  sing Y N 3   
A1IGD C05 C04  doub Y N 4   
A1IGD O07 N06  sing N N 5   
A1IGD O08 N06  doub N N 6   
A1IGD N06 C05  sing N N 7   
A1IGD C09 C05  sing Y N 8   
A1IGD C10 C09  doub Y N 9   
A1IGD N11 C10  sing N N 10  
A1IGD O12 N11  sing N N 11  
A1IGD O13 N11  doub N N 12  
A1IGD C02 C10  sing Y N 13  
A1IGD C03 H031 sing N N 14  
A1IGD C04 H041 sing N N 15  
A1IGD C09 H091 sing N N 16  
ALA   N   CA   sing N N 17  
ALA   N   H    sing N N 18  
ALA   N   H2   sing N N 19  
ALA   CA  C    sing N N 20  
ALA   CA  CB   sing N N 21  
ALA   CA  HA   sing N N 22  
ALA   C   O    doub N N 23  
ALA   C   OXT  sing N N 24  
ALA   CB  HB1  sing N N 25  
ALA   CB  HB2  sing N N 26  
ALA   CB  HB3  sing N N 27  
ALA   OXT HXT  sing N N 28  
ARG   N   CA   sing N N 29  
ARG   N   H    sing N N 30  
ARG   N   H2   sing N N 31  
ARG   CA  C    sing N N 32  
ARG   CA  CB   sing N N 33  
ARG   CA  HA   sing N N 34  
ARG   C   O    doub N N 35  
ARG   C   OXT  sing N N 36  
ARG   CB  CG   sing N N 37  
ARG   CB  HB2  sing N N 38  
ARG   CB  HB3  sing N N 39  
ARG   CG  CD   sing N N 40  
ARG   CG  HG2  sing N N 41  
ARG   CG  HG3  sing N N 42  
ARG   CD  NE   sing N N 43  
ARG   CD  HD2  sing N N 44  
ARG   CD  HD3  sing N N 45  
ARG   NE  CZ   sing N N 46  
ARG   NE  HE   sing N N 47  
ARG   CZ  NH1  sing N N 48  
ARG   CZ  NH2  doub N N 49  
ARG   NH1 HH11 sing N N 50  
ARG   NH1 HH12 sing N N 51  
ARG   NH2 HH21 sing N N 52  
ARG   NH2 HH22 sing N N 53  
ARG   OXT HXT  sing N N 54  
ASN   N   CA   sing N N 55  
ASN   N   H    sing N N 56  
ASN   N   H2   sing N N 57  
ASN   CA  C    sing N N 58  
ASN   CA  CB   sing N N 59  
ASN   CA  HA   sing N N 60  
ASN   C   O    doub N N 61  
ASN   C   OXT  sing N N 62  
ASN   CB  CG   sing N N 63  
ASN   CB  HB2  sing N N 64  
ASN   CB  HB3  sing N N 65  
ASN   CG  OD1  doub N N 66  
ASN   CG  ND2  sing N N 67  
ASN   ND2 HD21 sing N N 68  
ASN   ND2 HD22 sing N N 69  
ASN   OXT HXT  sing N N 70  
ASP   N   CA   sing N N 71  
ASP   N   H    sing N N 72  
ASP   N   H2   sing N N 73  
ASP   CA  C    sing N N 74  
ASP   CA  CB   sing N N 75  
ASP   CA  HA   sing N N 76  
ASP   C   O    doub N N 77  
ASP   C   OXT  sing N N 78  
ASP   CB  CG   sing N N 79  
ASP   CB  HB2  sing N N 80  
ASP   CB  HB3  sing N N 81  
ASP   CG  OD1  doub N N 82  
ASP   CG  OD2  sing N N 83  
ASP   OD2 HD2  sing N N 84  
ASP   OXT HXT  sing N N 85  
CYS   N   CA   sing N N 86  
CYS   N   H    sing N N 87  
CYS   N   H2   sing N N 88  
CYS   CA  C    sing N N 89  
CYS   CA  CB   sing N N 90  
CYS   CA  HA   sing N N 91  
CYS   C   O    doub N N 92  
CYS   C   OXT  sing N N 93  
CYS   CB  SG   sing N N 94  
CYS   CB  HB2  sing N N 95  
CYS   CB  HB3  sing N N 96  
CYS   SG  HG   sing N N 97  
CYS   OXT HXT  sing N N 98  
GLN   N   CA   sing N N 99  
GLN   N   H    sing N N 100 
GLN   N   H2   sing N N 101 
GLN   CA  C    sing N N 102 
GLN   CA  CB   sing N N 103 
GLN   CA  HA   sing N N 104 
GLN   C   O    doub N N 105 
GLN   C   OXT  sing N N 106 
GLN   CB  CG   sing N N 107 
GLN   CB  HB2  sing N N 108 
GLN   CB  HB3  sing N N 109 
GLN   CG  CD   sing N N 110 
GLN   CG  HG2  sing N N 111 
GLN   CG  HG3  sing N N 112 
GLN   CD  OE1  doub N N 113 
GLN   CD  NE2  sing N N 114 
GLN   NE2 HE21 sing N N 115 
GLN   NE2 HE22 sing N N 116 
GLN   OXT HXT  sing N N 117 
GLU   N   CA   sing N N 118 
GLU   N   H    sing N N 119 
GLU   N   H2   sing N N 120 
GLU   CA  C    sing N N 121 
GLU   CA  CB   sing N N 122 
GLU   CA  HA   sing N N 123 
GLU   C   O    doub N N 124 
GLU   C   OXT  sing N N 125 
GLU   CB  CG   sing N N 126 
GLU   CB  HB2  sing N N 127 
GLU   CB  HB3  sing N N 128 
GLU   CG  CD   sing N N 129 
GLU   CG  HG2  sing N N 130 
GLU   CG  HG3  sing N N 131 
GLU   CD  OE1  doub N N 132 
GLU   CD  OE2  sing N N 133 
GLU   OE2 HE2  sing N N 134 
GLU   OXT HXT  sing N N 135 
GLY   N   CA   sing N N 136 
GLY   N   H    sing N N 137 
GLY   N   H2   sing N N 138 
GLY   CA  C    sing N N 139 
GLY   CA  HA2  sing N N 140 
GLY   CA  HA3  sing N N 141 
GLY   C   O    doub N N 142 
GLY   C   OXT  sing N N 143 
GLY   OXT HXT  sing N N 144 
HIS   N   CA   sing N N 145 
HIS   N   H    sing N N 146 
HIS   N   H2   sing N N 147 
HIS   CA  C    sing N N 148 
HIS   CA  CB   sing N N 149 
HIS   CA  HA   sing N N 150 
HIS   C   O    doub N N 151 
HIS   C   OXT  sing N N 152 
HIS   CB  CG   sing N N 153 
HIS   CB  HB2  sing N N 154 
HIS   CB  HB3  sing N N 155 
HIS   CG  ND1  sing Y N 156 
HIS   CG  CD2  doub Y N 157 
HIS   ND1 CE1  doub Y N 158 
HIS   ND1 HD1  sing N N 159 
HIS   CD2 NE2  sing Y N 160 
HIS   CD2 HD2  sing N N 161 
HIS   CE1 NE2  sing Y N 162 
HIS   CE1 HE1  sing N N 163 
HIS   NE2 HE2  sing N N 164 
HIS   OXT HXT  sing N N 165 
HOH   O   H1   sing N N 166 
HOH   O   H2   sing N N 167 
ILE   N   CA   sing N N 168 
ILE   N   H    sing N N 169 
ILE   N   H2   sing N N 170 
ILE   CA  C    sing N N 171 
ILE   CA  CB   sing N N 172 
ILE   CA  HA   sing N N 173 
ILE   C   O    doub N N 174 
ILE   C   OXT  sing N N 175 
ILE   CB  CG1  sing N N 176 
ILE   CB  CG2  sing N N 177 
ILE   CB  HB   sing N N 178 
ILE   CG1 CD1  sing N N 179 
ILE   CG1 HG12 sing N N 180 
ILE   CG1 HG13 sing N N 181 
ILE   CG2 HG21 sing N N 182 
ILE   CG2 HG22 sing N N 183 
ILE   CG2 HG23 sing N N 184 
ILE   CD1 HD11 sing N N 185 
ILE   CD1 HD12 sing N N 186 
ILE   CD1 HD13 sing N N 187 
ILE   OXT HXT  sing N N 188 
LEU   N   CA   sing N N 189 
LEU   N   H    sing N N 190 
LEU   N   H2   sing N N 191 
LEU   CA  C    sing N N 192 
LEU   CA  CB   sing N N 193 
LEU   CA  HA   sing N N 194 
LEU   C   O    doub N N 195 
LEU   C   OXT  sing N N 196 
LEU   CB  CG   sing N N 197 
LEU   CB  HB2  sing N N 198 
LEU   CB  HB3  sing N N 199 
LEU   CG  CD1  sing N N 200 
LEU   CG  CD2  sing N N 201 
LEU   CG  HG   sing N N 202 
LEU   CD1 HD11 sing N N 203 
LEU   CD1 HD12 sing N N 204 
LEU   CD1 HD13 sing N N 205 
LEU   CD2 HD21 sing N N 206 
LEU   CD2 HD22 sing N N 207 
LEU   CD2 HD23 sing N N 208 
LEU   OXT HXT  sing N N 209 
LYS   N   CA   sing N N 210 
LYS   N   H    sing N N 211 
LYS   N   H2   sing N N 212 
LYS   CA  C    sing N N 213 
LYS   CA  CB   sing N N 214 
LYS   CA  HA   sing N N 215 
LYS   C   O    doub N N 216 
LYS   C   OXT  sing N N 217 
LYS   CB  CG   sing N N 218 
LYS   CB  HB2  sing N N 219 
LYS   CB  HB3  sing N N 220 
LYS   CG  CD   sing N N 221 
LYS   CG  HG2  sing N N 222 
LYS   CG  HG3  sing N N 223 
LYS   CD  CE   sing N N 224 
LYS   CD  HD2  sing N N 225 
LYS   CD  HD3  sing N N 226 
LYS   CE  NZ   sing N N 227 
LYS   CE  HE2  sing N N 228 
LYS   CE  HE3  sing N N 229 
LYS   NZ  HZ1  sing N N 230 
LYS   NZ  HZ2  sing N N 231 
LYS   NZ  HZ3  sing N N 232 
LYS   OXT HXT  sing N N 233 
MET   N   CA   sing N N 234 
MET   N   H    sing N N 235 
MET   N   H2   sing N N 236 
MET   CA  C    sing N N 237 
MET   CA  CB   sing N N 238 
MET   CA  HA   sing N N 239 
MET   C   O    doub N N 240 
MET   C   OXT  sing N N 241 
MET   CB  CG   sing N N 242 
MET   CB  HB2  sing N N 243 
MET   CB  HB3  sing N N 244 
MET   CG  SD   sing N N 245 
MET   CG  HG2  sing N N 246 
MET   CG  HG3  sing N N 247 
MET   SD  CE   sing N N 248 
MET   CE  HE1  sing N N 249 
MET   CE  HE2  sing N N 250 
MET   CE  HE3  sing N N 251 
MET   OXT HXT  sing N N 252 
PEG   C1  O1   sing N N 253 
PEG   C1  C2   sing N N 254 
PEG   C1  H11  sing N N 255 
PEG   C1  H12  sing N N 256 
PEG   O1  HO1  sing N N 257 
PEG   C2  O2   sing N N 258 
PEG   C2  H21  sing N N 259 
PEG   C2  H22  sing N N 260 
PEG   O2  C3   sing N N 261 
PEG   C3  C4   sing N N 262 
PEG   C3  H31  sing N N 263 
PEG   C3  H32  sing N N 264 
PEG   C4  O4   sing N N 265 
PEG   C4  H41  sing N N 266 
PEG   C4  H42  sing N N 267 
PEG   O4  HO4  sing N N 268 
PHE   N   CA   sing N N 269 
PHE   N   H    sing N N 270 
PHE   N   H2   sing N N 271 
PHE   CA  C    sing N N 272 
PHE   CA  CB   sing N N 273 
PHE   CA  HA   sing N N 274 
PHE   C   O    doub N N 275 
PHE   C   OXT  sing N N 276 
PHE   CB  CG   sing N N 277 
PHE   CB  HB2  sing N N 278 
PHE   CB  HB3  sing N N 279 
PHE   CG  CD1  doub Y N 280 
PHE   CG  CD2  sing Y N 281 
PHE   CD1 CE1  sing Y N 282 
PHE   CD1 HD1  sing N N 283 
PHE   CD2 CE2  doub Y N 284 
PHE   CD2 HD2  sing N N 285 
PHE   CE1 CZ   doub Y N 286 
PHE   CE1 HE1  sing N N 287 
PHE   CE2 CZ   sing Y N 288 
PHE   CE2 HE2  sing N N 289 
PHE   CZ  HZ   sing N N 290 
PHE   OXT HXT  sing N N 291 
PRO   N   CA   sing N N 292 
PRO   N   CD   sing N N 293 
PRO   N   H    sing N N 294 
PRO   CA  C    sing N N 295 
PRO   CA  CB   sing N N 296 
PRO   CA  HA   sing N N 297 
PRO   C   O    doub N N 298 
PRO   C   OXT  sing N N 299 
PRO   CB  CG   sing N N 300 
PRO   CB  HB2  sing N N 301 
PRO   CB  HB3  sing N N 302 
PRO   CG  CD   sing N N 303 
PRO   CG  HG2  sing N N 304 
PRO   CG  HG3  sing N N 305 
PRO   CD  HD2  sing N N 306 
PRO   CD  HD3  sing N N 307 
PRO   OXT HXT  sing N N 308 
SER   N   CA   sing N N 309 
SER   N   H    sing N N 310 
SER   N   H2   sing N N 311 
SER   CA  C    sing N N 312 
SER   CA  CB   sing N N 313 
SER   CA  HA   sing N N 314 
SER   C   O    doub N N 315 
SER   C   OXT  sing N N 316 
SER   CB  OG   sing N N 317 
SER   CB  HB2  sing N N 318 
SER   CB  HB3  sing N N 319 
SER   OG  HG   sing N N 320 
SER   OXT HXT  sing N N 321 
THR   N   CA   sing N N 322 
THR   N   H    sing N N 323 
THR   N   H2   sing N N 324 
THR   CA  C    sing N N 325 
THR   CA  CB   sing N N 326 
THR   CA  HA   sing N N 327 
THR   C   O    doub N N 328 
THR   C   OXT  sing N N 329 
THR   CB  OG1  sing N N 330 
THR   CB  CG2  sing N N 331 
THR   CB  HB   sing N N 332 
THR   OG1 HG1  sing N N 333 
THR   CG2 HG21 sing N N 334 
THR   CG2 HG22 sing N N 335 
THR   CG2 HG23 sing N N 336 
THR   OXT HXT  sing N N 337 
TRP   N   CA   sing N N 338 
TRP   N   H    sing N N 339 
TRP   N   H2   sing N N 340 
TRP   CA  C    sing N N 341 
TRP   CA  CB   sing N N 342 
TRP   CA  HA   sing N N 343 
TRP   C   O    doub N N 344 
TRP   C   OXT  sing N N 345 
TRP   CB  CG   sing N N 346 
TRP   CB  HB2  sing N N 347 
TRP   CB  HB3  sing N N 348 
TRP   CG  CD1  doub Y N 349 
TRP   CG  CD2  sing Y N 350 
TRP   CD1 NE1  sing Y N 351 
TRP   CD1 HD1  sing N N 352 
TRP   CD2 CE2  doub Y N 353 
TRP   CD2 CE3  sing Y N 354 
TRP   NE1 CE2  sing Y N 355 
TRP   NE1 HE1  sing N N 356 
TRP   CE2 CZ2  sing Y N 357 
TRP   CE3 CZ3  doub Y N 358 
TRP   CE3 HE3  sing N N 359 
TRP   CZ2 CH2  doub Y N 360 
TRP   CZ2 HZ2  sing N N 361 
TRP   CZ3 CH2  sing Y N 362 
TRP   CZ3 HZ3  sing N N 363 
TRP   CH2 HH2  sing N N 364 
TRP   OXT HXT  sing N N 365 
TYR   N   CA   sing N N 366 
TYR   N   H    sing N N 367 
TYR   N   H2   sing N N 368 
TYR   CA  C    sing N N 369 
TYR   CA  CB   sing N N 370 
TYR   CA  HA   sing N N 371 
TYR   C   O    doub N N 372 
TYR   C   OXT  sing N N 373 
TYR   CB  CG   sing N N 374 
TYR   CB  HB2  sing N N 375 
TYR   CB  HB3  sing N N 376 
TYR   CG  CD1  doub Y N 377 
TYR   CG  CD2  sing Y N 378 
TYR   CD1 CE1  sing Y N 379 
TYR   CD1 HD1  sing N N 380 
TYR   CD2 CE2  doub Y N 381 
TYR   CD2 HD2  sing N N 382 
TYR   CE1 CZ   doub Y N 383 
TYR   CE1 HE1  sing N N 384 
TYR   CE2 CZ   sing Y N 385 
TYR   CE2 HE2  sing N N 386 
TYR   CZ  OH   sing N N 387 
TYR   OH  HH   sing N N 388 
TYR   OXT HXT  sing N N 389 
VAL   N   CA   sing N N 390 
VAL   N   H    sing N N 391 
VAL   N   H2   sing N N 392 
VAL   CA  C    sing N N 393 
VAL   CA  CB   sing N N 394 
VAL   CA  HA   sing N N 395 
VAL   C   O    doub N N 396 
VAL   C   OXT  sing N N 397 
VAL   CB  CG1  sing N N 398 
VAL   CB  CG2  sing N N 399 
VAL   CB  HB   sing N N 400 
VAL   CG1 HG11 sing N N 401 
VAL   CG1 HG12 sing N N 402 
VAL   CG1 HG13 sing N N 403 
VAL   CG2 HG21 sing N N 404 
VAL   CG2 HG22 sing N N 405 
VAL   CG2 HG23 sing N N 406 
VAL   OXT HXT  sing N N 407 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'UK Research and Innovation (UKRI)'                  'United Kingdom' BB/W014483/1 1 
'Engineering and Physical Sciences Research Council' 'United Kingdom' EP/023755/1  2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7O1D 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 31 2 1' 
_space_group.name_Hall        
;P 31 2"
;
_space_group.IT_number        152 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9FUG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014212 
_atom_sites.fract_transf_matrix[1][2]   0.008205 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.016410 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008367 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580  ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761  7.44341  ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472  ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
I  ? ? 40.26819 12.56501 ? ? 1.42647  27.02115 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436  ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563  ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887  ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . MET   A 1 1   ? 19.71712 -10.77251 34.35008  1.000 42.64297  ? 1   MET   A N    1 
ATOM   2    C  CA   . MET   A 1 1   ? 21.18845 -10.95394 34.27791  1.000 38.40354  ? 1   MET   A CA   1 
ATOM   3    C  C    . MET   A 1 1   ? 21.65391 -10.86745 32.82444  1.000 32.67779  ? 1   MET   A C    1 
ATOM   4    O  O    . MET   A 1 1   ? 20.85320 -10.95671 31.90126  1.000 43.74652  ? 1   MET   A O    1 
ATOM   5    C  CB   . MET   A 1 1   ? 21.61798 -12.30257 34.87454  1.000 49.23389  ? 1   MET   A CB   1 
ATOM   6    C  CG   . MET   A 1 1   ? 21.16006 -13.52399 34.10948  1.000 54.54102  ? 1   MET   A CG   1 
ATOM   7    S  SD   . MET   A 1 1   ? 21.76959 -15.10288 34.79279  1.000 38.40029  ? 1   MET   A SD   1 
ATOM   8    C  CE   . MET   A 1 1   ? 21.26806 -14.89906 36.48908  1.000 41.94341  ? 1   MET   A CE   1 
ATOM   9    H  H1   . MET   A 1 1   ? 19.53088 -10.04771 34.83183  1.000 51.18583  ? 1   MET   A H1   1 
ATOM   10   H  H2   . MET   A 1 1   ? 19.38961 -10.67479 33.52832  1.000 51.18583  ? 1   MET   A H2   1 
ATOM   11   H  H3   . MET   A 1 1   ? 19.34866 -11.48625 34.73337  1.000 51.18583  ? 1   MET   A H3   1 
ATOM   12   H  HA   . MET   A 1 1   ? 21.61169 -10.25927 34.80631  1.000 46.09852  ? 1   MET   A HA   1 
ATOM   13   H  HB2  . MET   A 1 1   ? 22.58712 -12.32778 34.90669  1.000 59.09494  ? 1   MET   A HB2  1 
ATOM   14   H  HB3  . MET   A 1 1   ? 21.25444 -12.36972 35.77132  1.000 59.09494  ? 1   MET   A HB3  1 
ATOM   15   H  HG2  . MET   A 1 1   ? 20.19057 -13.55292 34.12136  1.000 65.46349  ? 1   MET   A HG2  1 
ATOM   16   H  HG3  . MET   A 1 1   ? 21.47876 -13.45616 33.19584  1.000 65.46349  ? 1   MET   A HG3  1 
ATOM   17   H  HE1  . MET   A 1 1   ? 21.37500 -15.74381 36.95369  1.000 50.34636  ? 1   MET   A HE1  1 
ATOM   18   H  HE2  . MET   A 1 1   ? 21.82415 -14.22089 36.90350  1.000 50.34636  ? 1   MET   A HE2  1 
ATOM   19   H  HE3  . MET   A 1 1   ? 20.33816 -14.62404 36.51258  1.000 50.34636  ? 1   MET   A HE3  1 
ATOM   20   N  N    . ILE   A 1 2   ? 22.95514 -10.71199 32.64654  1.000 39.26326  ? 2   ILE   A N    1 
ATOM   21   C  CA   . ILE   A 1 2   ? 23.55882 -10.73688 31.31916  1.000 37.02033  ? 2   ILE   A CA   1 
ATOM   22   C  C    . ILE   A 1 2   ? 23.96450 -12.17423 31.03540  1.000 31.72028  ? 2   ILE   A C    1 
ATOM   23   O  O    . ILE   A 1 2   ? 24.69941 -12.78924 31.81031  1.000 37.43927  ? 2   ILE   A O    1 
ATOM   24   C  CB   . ILE   A 1 2   ? 24.76531 -9.79495  31.22416  1.000 35.28973  ? 2   ILE   A CB   1 
ATOM   25   C  CG1  . ILE   A 1 2   ? 24.33493 -8.34855  31.46357  1.000 38.12467  ? 2   ILE   A CG1  1 
ATOM   26   C  CG2  . ILE   A 1 2   ? 25.44915 -9.94229  29.85465  1.000 32.89627  ? 2   ILE   A CG2  1 
ATOM   27   C  CD1  . ILE   A 1 2   ? 23.20166 -7.86411  30.60778  1.000 34.28963  ? 2   ILE   A CD1  1 
ATOM   28   H  H    . ILE   A 1 2   ? 23.51858 -10.58895 33.28451  1.000 47.13018  ? 2   ILE   A H    1 
ATOM   29   H  HA   . ILE   A 1 2   ? 22.90872 -10.44863 30.65947  1.000 44.43867  ? 2   ILE   A HA   1 
ATOM   30   H  HB   . ILE   A 1 2   ? 25.40204 -10.03886 31.91407  1.000 42.36195  ? 2   ILE   A HB   1 
ATOM   31   H  HG12 . ILE   A 1 2   ? 24.05606 -8.26193  32.38857  1.000 45.76387  ? 2   ILE   A HG12 1 
ATOM   32   H  HG13 . ILE   A 1 2   ? 25.09492 -7.77110  31.29072  1.000 45.76387  ? 2   ILE   A HG13 1 
ATOM   33   H  HG21 . ILE   A 1 2   ? 26.15690 -9.28291  29.78249  1.000 39.48980  ? 2   ILE   A HG21 1 
ATOM   34   H  HG22 . ILE   A 1 2   ? 25.82045 -10.83542 29.78153  1.000 39.48980  ? 2   ILE   A HG22 1 
ATOM   35   H  HG23 . ILE   A 1 2   ? 24.79139 -9.79931  29.15621  1.000 39.48980  ? 2   ILE   A HG23 1 
ATOM   36   H  HD11 . ILE   A 1 2   ? 23.14430 -6.89827  30.67677  1.000 41.16183  ? 2   ILE   A HD11 1 
ATOM   37   H  HD12 . ILE   A 1 2   ? 23.36892 -8.12063  29.68739  1.000 41.16183  ? 2   ILE   A HD12 1 
ATOM   38   H  HD13 . ILE   A 1 2   ? 22.37620 -8.26755  30.91882  1.000 41.16183  ? 2   ILE   A HD13 1 
ATOM   39   N  N    . ARG   A 1 3   ? 23.47360 -12.71835 29.92716  1.000 30.94200  ? 3   ARG   A N    1 
ATOM   40   C  CA   . ARG   A 1 3   ? 23.85554 -14.05887 29.51861  1.000 32.18927  ? 3   ARG   A CA   1 
ATOM   41   C  C    . ARG   A 1 3   ? 24.50380 -14.11467 28.15082  1.000 29.37800  ? 3   ARG   A C    1 
ATOM   42   O  O    . ARG   A 1 3   ? 24.95786 -15.19544 27.74725  1.000 31.02371  ? 3   ARG   A O    1 
ATOM   43   C  CB   . ARG   A 1 3   ? 22.62845 -14.97107 29.51889  1.000 39.72520  ? 3   ARG   A CB   1 
ATOM   44   C  CG   . ARG   A 1 3   ? 22.12476 -15.24167 30.93742  1.000 37.73729  ? 3   ARG   A CG   1 
ATOM   45   C  CD   . ARG   A 1 3   ? 20.72496 -15.72503 30.88642  1.000 37.66044  ? 3   ARG   A CD   1 
ATOM   46   N  NE   . ARG   A 1 3   ? 20.62369 -16.98086 30.16071  1.000 35.45660  ? 3   ARG   A NE   1 
ATOM   47   C  CZ   . ARG   A 1 3   ? 19.47113 -17.52789 29.80776  1.000 31.53910  ? 3   ARG   A CZ   1 
ATOM   48   N  NH1  . ARG   A 1 3   ? 18.32091 -16.94419 30.09166  1.000 40.89142  ? 3   ARG   A NH1  1 
ATOM   49   N  NH2  . ARG   A 1 3   ? 19.48124 -18.66476 29.12885  1.000 40.25265  ? 3   ARG   A NH2  1 
ATOM   50   H  H    . ARG   A 1 3   ? 22.91863 -12.32926 29.39779  1.000 37.14467  ? 3   ARG   A H    1 
ATOM   51   H  HA   . ARG   A 1 3   ? 24.49357 -14.41080 30.15890  1.000 38.64139  ? 3   ARG   A HA   1 
ATOM   52   H  HB2  . ARG   A 1 3   ? 21.91455 -14.54668 29.01775  1.000 47.68452  ? 3   ARG   A HB2  1 
ATOM   53   H  HB3  . ARG   A 1 3   ? 22.86102 -15.81983 29.11095  1.000 47.68452  ? 3   ARG   A HB3  1 
ATOM   54   H  HG2  . ARG   A 1 3   ? 22.67497 -15.92151 31.35693  1.000 45.29902  ? 3   ARG   A HG2  1 
ATOM   55   H  HG3  . ARG   A 1 3   ? 22.15404 -14.42355 31.45772  1.000 45.29902  ? 3   ARG   A HG3  1 
ATOM   56   H  HD2  . ARG   A 1 3   ? 20.40075 -15.86705 31.78954  1.000 45.20679  ? 3   ARG   A HD2  1 
ATOM   57   H  HD3  . ARG   A 1 3   ? 20.17360 -15.06640 30.43574  1.000 45.20679  ? 3   ARG   A HD3  1 
ATOM   58   H  HE   . ARG   A 1 3   ? 21.35040 -17.38953 29.94980  1.000 42.56219  ? 3   ARG   A HE   1 
ATOM   59   H  HH11 . ARG   A 1 3   ? 18.31158 -16.19473 30.51335  1.000 49.08398  ? 3   ARG   A HH11 1 
ATOM   60   H  HH12 . ARG   A 1 3   ? 17.58127 -17.31357 29.85484  1.000 49.08398  ? 3   ARG   A HH12 1 
ATOM   61   H  HH21 . ARG   A 1 3   ? 20.22914 -19.03649 28.92377  1.000 48.31746  ? 3   ARG   A HH21 1 
ATOM   62   H  HH22 . ARG   A 1 3   ? 18.73991 -19.03137 28.89302  1.000 48.31746  ? 3   ARG   A HH22 1 
ATOM   63   N  N    . ALA   A 1 4   ? 24.55076 -12.99990 27.43242  1.000 30.38640  ? 4   ALA   A N    1 
ATOM   64   C  CA   . ALA   A 1 4   ? 25.13141 -12.96009 26.09194  1.000 31.83468  ? 4   ALA   A CA   1 
ATOM   65   C  C    . ALA   A 1 4   ? 25.93898 -11.67968 25.93848  1.000 33.16291  ? 4   ALA   A C    1 
ATOM   66   O  O    . ALA   A 1 4   ? 25.52284 -10.61408 26.40033  1.000 31.60101  ? 4   ALA   A O    1 
ATOM   67   C  CB   . ALA   A 1 4   ? 24.04997 -13.02809 25.01914  1.000 29.54797  ? 4   ALA   A CB   1 
ATOM   68   H  H    . ALA   A 1 4   ? 24.24881 -12.24099 27.70165  1.000 36.47795  ? 4   ALA   A H    1 
ATOM   69   H  HA   . ALA   A 1 4   ? 25.72889 -13.71416 25.96827  1.000 38.21589  ? 4   ALA   A HA   1 
ATOM   70   H  HB1  . ALA   A 1 4   ? 24.46919 -12.98967 24.14525  1.000 35.47184  ? 4   ALA   A HB1  1 
ATOM   71   H  HB2  . ALA   A 1 4   ? 23.56156 -13.86061 25.11539  1.000 35.47184  ? 4   ALA   A HB2  1 
ATOM   72   H  HB3  . ALA   A 1 4   ? 23.44724 -12.27625 25.13021  1.000 35.47184  ? 4   ALA   A HB3  1 
ATOM   73   N  N    . VAL   A 1 5   ? 27.08176 -11.79330 25.27828  1.000 30.24012  ? 5   VAL   A N    1 
ATOM   74   C  CA   . VAL   A 1 5   ? 27.93720 -10.64637 24.97532  1.000 28.50817  ? 5   VAL   A CA   1 
ATOM   75   C  C    . VAL   A 1 5   ? 28.23770 -10.70481 23.47975  1.000 26.64612  ? 5   VAL   A C    1 
ATOM   76   O  O    . VAL   A 1 5   ? 28.79776 -11.69540 23.00383  1.000 31.27838  ? 5   VAL   A O    1 
ATOM   77   C  CB   . VAL   A 1 5   ? 29.23009 -10.65894 25.79905  1.000 32.07542  ? 5   VAL   A CB   1 
ATOM   78   C  CG1  . VAL   A 1 5   ? 30.08532 -9.43398  25.46791  1.000 34.86686  ? 5   VAL   A CG1  1 
ATOM   79   C  CG2  . VAL   A 1 5   ? 28.89669 -10.69498 27.29943  1.000 29.50301  ? 5   VAL   A CG2  1 
ATOM   80   H  H    . VAL   A 1 5   ? 27.39332 -12.54015 24.98716  1.000 36.30242  ? 5   VAL   A H    1 
ATOM   81   H  HA   . VAL   A 1 5   ? 27.47201 -9.81790  25.17059  1.000 34.22407  ? 5   VAL   A HA   1 
ATOM   82   H  HB   . VAL   A 1 5   ? 29.74245 -11.45243 25.57824  1.000 38.50477  ? 5   VAL   A HB   1 
ATOM   83   H  HG11 . VAL   A 1 5   ? 30.73443 -9.30115  26.17636  1.000 41.85450  ? 5   VAL   A HG11 1 
ATOM   84   H  HG12 . VAL   A 1 5   ? 30.54154 -9.58575  24.62546  1.000 41.85450  ? 5   VAL   A HG12 1 
ATOM   85   H  HG13 . VAL   A 1 5   ? 29.50947 -8.65664  25.39688  1.000 41.85450  ? 5   VAL   A HG13 1 
ATOM   86   H  HG21 . VAL   A 1 5   ? 29.72089 -10.63677 27.80757  1.000 35.41788  ? 5   VAL   A HG21 1 
ATOM   87   H  HG22 . VAL   A 1 5   ? 28.32235 -9.94317  27.51346  1.000 35.41788  ? 5   VAL   A HG22 1 
ATOM   88   H  HG23 . VAL   A 1 5   ? 28.44139 -11.52722 27.50186  1.000 35.41788  ? 5   VAL   A HG23 1 
ATOM   89   N  N    . PHE   A 1 6   ? 27.86455 -9.65809  22.75263  1.000 29.76157  ? 6   PHE   A N    1 
ATOM   90   C  CA   . PHE   A 1 6   ? 28.02077 -9.57844  21.30441  1.000 27.65932  ? 6   PHE   A CA   1 
ATOM   91   C  C    . PHE   A 1 6   ? 29.05159 -8.51434  20.93812  1.000 33.09536  ? 6   PHE   A C    1 
ATOM   92   O  O    . PHE   A 1 6   ? 29.10912 -7.44719  21.56394  1.000 32.78600  ? 6   PHE   A O    1 
ATOM   93   C  CB   . PHE   A 1 6   ? 26.69147 -9.25385  20.64042  1.000 25.96791  ? 6   PHE   A CB   1 
ATOM   94   C  CG   . PHE   A 1 6   ? 25.67622 -10.35926 20.74574  1.000 31.02706  ? 6   PHE   A CG   1 
ATOM   95   C  CD1  . PHE   A 1 6   ? 25.67903 -11.41279 19.84610  1.000 32.11614  ? 6   PHE   A CD1  1 
ATOM   96   C  CD2  . PHE   A 1 6   ? 24.71558 -10.33581 21.74218  1.000 31.87712  ? 6   PHE   A CD2  1 
ATOM   97   C  CE1  . PHE   A 1 6   ? 24.75854 -12.42859 19.94730  1.000 36.74640  ? 6   PHE   A CE1  1 
ATOM   98   C  CE2  . PHE   A 1 6   ? 23.78915 -11.36140 21.84793  1.000 29.69392  ? 6   PHE   A CE2  1 
ATOM   99   C  CZ   . PHE   A 1 6   ? 23.81418 -12.40289 20.95566  1.000 31.17371  ? 6   PHE   A CZ   1 
ATOM   100  H  H    . PHE   A 1 6   ? 27.50392 -8.95346  23.08884  1.000 35.72815  ? 6   PHE   A H    1 
ATOM   101  H  HA   . PHE   A 1 6   ? 28.33962 -10.43063 20.96824  1.000 33.20545  ? 6   PHE   A HA   1 
ATOM   102  H  HB2  . PHE   A 1 6   ? 26.31594 -8.46557  21.06291  1.000 31.17576  ? 6   PHE   A HB2  1 
ATOM   103  H  HB3  . PHE   A 1 6   ? 26.84679 -9.08314  19.69827  1.000 31.17576  ? 6   PHE   A HB3  1 
ATOM   104  H  HD1  . PHE   A 1 6   ? 26.31187 -11.43301 19.16491  1.000 38.55363  ? 6   PHE   A HD1  1 
ATOM   105  H  HD2  . PHE   A 1 6   ? 24.69164 -9.62753  22.34440  1.000 38.26681  ? 6   PHE   A HD2  1 
ATOM   106  H  HE1  . PHE   A 1 6   ? 24.77131 -13.13152 19.33851  1.000 44.10995  ? 6   PHE   A HE1  1 
ATOM   107  H  HE2  . PHE   A 1 6   ? 23.15060 -11.34337 22.52382  1.000 35.64698  ? 6   PHE   A HE2  1 
ATOM   108  H  HZ   . PHE   A 1 6   ? 23.19474 -13.09263 21.02948  1.000 37.42272  ? 6   PHE   A HZ   1 
ATOM   109  N  N    . PHE   A 1 7   ? 29.85863 -8.81292  19.92557  1.000 31.04930  ? 7   PHE   A N    1 
ATOM   110  C  CA   . PHE   A 1 7   ? 30.90100 -7.94024  19.42453  1.000 29.96808  ? 7   PHE   A CA   1 
ATOM   111  C  C    . PHE   A 1 7   ? 30.68036 -7.67069  17.93421  1.000 38.70535  ? 7   PHE   A C    1 
ATOM   112  O  O    . PHE   A 1 7   ? 29.83804 -8.28306  17.28220  1.000 30.56462  ? 7   PHE   A O    1 
ATOM   113  C  CB   . PHE   A 1 7   ? 32.28897 -8.56358  19.61169  1.000 31.24417  ? 7   PHE   A CB   1 
ATOM   114  C  CG   . PHE   A 1 7   ? 32.66334 -8.80229  21.03483  1.000 31.82996  ? 7   PHE   A CG   1 
ATOM   115  C  CD1  . PHE   A 1 7   ? 32.26044 -9.96251  21.69054  1.000 29.81002  ? 7   PHE   A CD1  1 
ATOM   116  C  CD2  . PHE   A 1 7   ? 33.42335 -7.88133  21.72819  1.000 29.88250  ? 7   PHE   A CD2  1 
ATOM   117  C  CE1  . PHE   A 1 7   ? 32.60339 -10.18752 23.00581  1.000 36.16493  ? 7   PHE   A CE1  1 
ATOM   118  C  CE2  . PHE   A 1 7   ? 33.76834 -8.10059  23.04098  1.000 34.31491  ? 7   PHE   A CE2  1 
ATOM   119  C  CZ   . PHE   A 1 7   ? 33.35988 -9.25688  23.68570  1.000 38.70326  ? 7   PHE   A CZ   1 
ATOM   120  H  H    . PHE   A 1 7   ? 29.81526 -9.55534  19.49368  1.000 37.27343  ? 7   PHE   A H    1 
ATOM   121  H  HA   . PHE   A 1 7   ? 30.86141 -7.10287  19.91254  1.000 35.97596  ? 7   PHE   A HA   1 
ATOM   122  H  HB2  . PHE   A 1 7   ? 32.30933 -9.41883  19.15448  1.000 37.50727  ? 7   PHE   A HB2  1 
ATOM   123  H  HB3  . PHE   A 1 7   ? 32.95129 -7.96703  19.22913  1.000 37.50727  ? 7   PHE   A HB3  1 
ATOM   124  H  HD1  . PHE   A 1 7   ? 31.75282 -10.59433 21.23443  1.000 35.78629  ? 7   PHE   A HD1  1 
ATOM   125  H  HD2  . PHE   A 1 7   ? 33.70507 -7.10397  21.30246  1.000 35.87327  ? 7   PHE   A HD2  1 
ATOM   126  H  HE1  . PHE   A 1 7   ? 32.32536 -10.96498 23.43378  1.000 43.41218  ? 7   PHE   A HE1  1 
ATOM   127  H  HE2  . PHE   A 1 7   ? 34.27760 -7.47057  23.49772  1.000 41.19216  ? 7   PHE   A HE2  1 
ATOM   128  H  HZ   . PHE   A 1 7   ? 33.59500 -9.40462  24.57327  1.000 46.45818  ? 7   PHE   A HZ   1 
ATOM   129  N  N    . ASP   A 1 8   ? 31.45430 -6.73191  17.40233  1.000 37.06361  ? 8   ASP   A N    1 
ATOM   130  C  CA   . ASP   A 1 8   ? 31.55601 -6.46985  15.95846  1.000 33.93592  ? 8   ASP   A CA   1 
ATOM   131  C  C    . ASP   A 1 8   ? 33.03109 -6.65829  15.62694  1.000 35.32079  ? 8   ASP   A C    1 
ATOM   132  O  O    . ASP   A 1 8   ? 33.80950 -5.70781  15.64008  1.000 45.01218  ? 8   ASP   A O    1 
ATOM   133  C  CB   . ASP   A 1 8   ? 31.05301 -5.08303  15.61596  1.000 40.28040  ? 8   ASP   A CB   1 
ATOM   134  C  CG   . ASP   A 1 8   ? 31.14099 -4.77566  14.12445  1.000 48.80920  ? 8   ASP   A CG   1 
ATOM   135  O  OD1  . ASP   A 1 8   ? 31.59806 -5.64175  13.32854  1.000 38.82422  ? 8   ASP   A OD1  1 
ATOM   136  O  OD2  . ASP   A 1 8   ? 30.74757 -3.65762  13.75226  1.000 44.42893  ? 8   ASP   A OD2  1 
ATOM   137  H  H    . ASP   A 1 8   ? 31.95190 -6.21017  17.87114  1.000 44.49060  ? 8   ASP   A H    1 
ATOM   138  H  HA   . ASP   A 1 8   ? 31.02084 -7.09615  15.44638  1.000 40.73738  ? 8   ASP   A HA   1 
ATOM   139  H  HB2  . ASP   A 1 8   ? 30.12351 -5.00887  15.88325  1.000 48.35075  ? 8   ASP   A HB2  1 
ATOM   140  H  HB3  . ASP   A 1 8   ? 31.58777 -4.42682  16.08957  1.000 48.35075  ? 8   ASP   A HB3  1 
ATOM   141  N  N    . SER   A 1 9   ? 33.42052 -7.89718  15.34924  1.000 31.78020  ? 9   SER   A N    1 
ATOM   142  C  CA   . SER   A 1 9   ? 34.82499 -8.25621  15.27888  1.000 29.80724  ? 9   SER   A CA   1 
ATOM   143  C  C    . SER   A 1 9   ? 35.50639 -7.54281  14.11760  1.000 51.54302  ? 9   SER   A C    1 
ATOM   144  O  O    . SER   A 1 9   ? 36.34172 -6.65493  14.33156  1.000 43.25931  ? 9   SER   A O    1 
ATOM   145  C  CB   . SER   A 1 9   ? 34.97107 -9.76661  15.12155  1.000 40.89523  ? 9   SER   A CB   1 
ATOM   146  O  OG   . SER   A 1 9   ? 34.41246 -10.18703 13.88074  1.000 56.21655  ? 9   SER   A OG   1 
ATOM   147  H  H    . SER   A 1 9   ? 32.88389 -8.55168  15.19672  1.000 38.15052  ? 9   SER   A H    1 
ATOM   148  H  HA   . SER   A 1 9   ? 35.26458 -7.98652  16.10042  1.000 35.78296  ? 9   SER   A HA   1 
ATOM   149  H  HB2  . SER   A 1 9   ? 35.91249 -9.99942  15.14219  1.000 49.08855  ? 9   SER   A HB2  1 
ATOM   150  H  HB3  . SER   A 1 9   ? 34.50390 -10.20911 15.84738  1.000 49.08855  ? 9   SER   A HB3  1 
ATOM   151  H  HG   . SER   A 1 9   ? 34.08077 -10.95465 13.96040  1.000 67.47413  ? 9   SER   A HG   1 
ATOM   152  N  N    . LEU   A 1 10  ? 35.15503 -7.93296  12.88625  1.000 45.79903  ? 10  LEU   A N    1 
ATOM   153  C  CA   . LEU   A 1 10  ? 35.82290 -7.40792  11.69929  1.000 58.91092  ? 10  LEU   A CA   1 
ATOM   154  C  C    . LEU   A 1 10  ? 35.59484 -5.91843  11.51288  1.000 69.93175  ? 10  LEU   A C    1 
ATOM   155  O  O    . LEU   A 1 10  ? 36.26230 -5.30902  10.66816  1.000 52.78719  ? 10  LEU   A O    1 
ATOM   156  C  CB   . LEU   A 1 10  ? 35.34508 -8.15384  10.45160  1.000 48.65698  ? 10  LEU   A CB   1 
ATOM   157  C  CG   . LEU   A 1 10  ? 35.41905 -9.68182  10.50934  1.000 38.81194  ? 10  LEU   A CG   1 
ATOM   158  C  CD1  . LEU   A 1 10  ? 34.95074 -10.31039 9.18359   1.000 38.17050  ? 10  LEU   A CD1  1 
ATOM   159  C  CD2  . LEU   A 1 10  ? 36.81492 -10.15124 10.85039  1.000 43.36008  ? 10  LEU   A CD2  1 
ATOM   160  H  H    . LEU   A 1 10  ? 34.53234 -8.50094  12.71518  1.000 54.97311  ? 10  LEU   A H    1 
ATOM   161  H  HA   . LEU   A 1 10  ? 36.77642 -7.55891  11.79360  1.000 70.70738  ? 10  LEU   A HA   1 
ATOM   162  H  HB2  . LEU   A 1 10  ? 34.41733 -7.91756  10.29551  1.000 58.40264  ? 10  LEU   A HB2  1 
ATOM   163  H  HB3  . LEU   A 1 10  ? 35.89070 -7.86866  9.70202   1.000 58.40264  ? 10  LEU   A HB3  1 
ATOM   164  H  HG   . LEU   A 1 10  ? 34.82323 -9.98428  11.21248  1.000 46.58860  ? 10  LEU   A HG   1 
ATOM   165  H  HD11 . LEU   A 1 10  ? 35.05124 -11.27363 9.23792   1.000 45.81887  ? 10  LEU   A HD11 1 
ATOM   166  H  HD12 . LEU   A 1 10  ? 34.01917 -10.08271 9.03784   1.000 45.81887  ? 10  LEU   A HD12 1 
ATOM   167  H  HD13 . LEU   A 1 10  ? 35.49373 -9.96147  8.45949   1.000 45.81887  ? 10  LEU   A HD13 1 
ATOM   168  H  HD21 . LEU   A 1 10  ? 36.85822 -11.11472 10.74678  1.000 52.04637  ? 10  LEU   A HD21 1 
ATOM   169  H  HD22 . LEU   A 1 10  ? 37.44680 -9.72529  10.25022  1.000 52.04637  ? 10  LEU   A HD22 1 
ATOM   170  H  HD23 . LEU   A 1 10  ? 37.01458 -9.90791  11.76790  1.000 52.04637  ? 10  LEU   A HD23 1 
ATOM   171  N  N    . GLY   A 1 11  ? 34.68017 -5.32421  12.27219  1.000 49.61623  ? 11  GLY   A N    1 
ATOM   172  C  CA   . GLY   A 1 11  ? 34.41607 -3.90850  12.15301  1.000 64.30959  ? 11  GLY   A CA   1 
ATOM   173  C  C    . GLY   A 1 11  ? 35.05682 -3.08970  13.25099  1.000 50.72232  ? 11  GLY   A C    1 
ATOM   174  O  O    . GLY   A 1 11  ? 35.32646 -1.89895  13.05974  1.000 58.00462  ? 11  GLY   A O    1 
ATOM   175  H  H    . GLY   A 1 11  ? 34.20141 -5.72535  12.86335  1.000 59.55375  ? 11  GLY   A H    1 
ATOM   176  H  HA2  . GLY   A 1 11  ? 34.75664 -3.59217  11.30163  1.000 77.18577  ? 11  GLY   A HA2  1 
ATOM   177  H  HA3  . GLY   A 1 11  ? 33.45801 -3.76010  12.18471  1.000 77.18577  ? 11  GLY   A HA3  1 
ATOM   178  N  N    . THR   A 1 12  ? 35.30007 -3.70675  14.40484  1.000 37.20532  ? 12  THR   A N    1 
ATOM   179  C  CA   . THR   A 1 12  ? 35.76974 -2.94173  15.56583  1.000 44.23167  ? 12  THR   A CA   1 
ATOM   180  C  C    . THR   A 1 12  ? 36.89187 -3.58322  16.36905  1.000 67.69788  ? 12  THR   A C    1 
ATOM   181  O  O    . THR   A 1 12  ? 37.45800 -2.89549  17.22469  1.000 61.79326  ? 12  THR   A O    1 
ATOM   182  C  CB   . THR   A 1 12  ? 34.60378 -2.67830  16.53791  1.000 62.33398  ? 12  THR   A CB   1 
ATOM   183  O  OG1  . THR   A 1 12  ? 34.21284 -3.91505  17.16777  1.000 48.13425  ? 12  THR   A OG1  1 
ATOM   184  C  CG2  . THR   A 1 12  ? 33.40869 -2.07094  15.80631  1.000 48.54740  ? 12  THR   A CG2  1 
ATOM   185  H  H    . THR   A 1 12  ? 35.20401 -4.55028  14.54204  1.000 44.66066  ? 12  THR   A H    1 
ATOM   186  H  HA   . THR   A 1 12  ? 36.10490 -2.09626  15.22857  1.000 53.09227  ? 12  THR   A HA   1 
ATOM   187  H  HB   . THR   A 1 12  ? 34.88742 -2.04660  17.21718  1.000 74.81505  ? 12  THR   A HB   1 
ATOM   188  H  HG1  . THR   A 1 12  ? 33.74170 -4.36927  16.64117  1.000 57.77537  ? 12  THR   A HG1  1 
ATOM   189  H  HG21 . THR   A 1 12  ? 32.77029 -1.72087  16.44723  1.000 58.27116  ? 12  THR   A HG21 1 
ATOM   190  H  HG22 . THR   A 1 12  ? 33.70445 -1.34887  15.23009  1.000 58.27116  ? 12  THR   A HG22 1 
ATOM   191  H  HG23 . THR   A 1 12  ? 32.97251 -2.74728  15.26481  1.000 58.27116  ? 12  THR   A HG23 1 
ATOM   192  N  N    . LEU   A 1 13  ? 37.22673 -4.85934  16.15430  1.000 64.22139  ? 13  LEU   A N    1 
ATOM   193  C  CA   A LEU   A 1 13  ? 38.28573 -5.51751  16.90893  0.700 39.01565  ? 13  LEU   A CA   1 
ATOM   194  C  CA   B LEU   A 1 13  ? 38.28157 -5.53338  16.90049  0.300 39.44558  ? 13  LEU   A CA   1 
ATOM   195  C  C    . LEU   A 1 13  ? 39.55634 -5.71049  16.08913  1.000 41.57174  ? 13  LEU   A C    1 
ATOM   196  O  O    . LEU   A 1 13  ? 40.49691 -6.35843  16.56859  1.000 37.12850  ? 13  LEU   A O    1 
ATOM   197  C  CB   A LEU   A 1 13  ? 37.80648 -6.86707  17.43016  0.700 37.44979  ? 13  LEU   A CB   1 
ATOM   198  C  CB   B LEU   A 1 13  ? 37.80024 -6.90157  17.38246  0.300 38.04408  ? 13  LEU   A CB   1 
ATOM   199  C  CG   A LEU   A 1 13  ? 36.54494 -6.82405  18.29031  0.700 43.43636  ? 13  LEU   A CG   1 
ATOM   200  C  CG   B LEU   A 1 13  ? 37.18243 -6.95590  18.77934  0.300 58.15332  ? 13  LEU   A CG   1 
ATOM   201  C  CD1  A LEU   A 1 13  ? 36.40021 -8.15847  19.01782  0.700 38.89516  ? 13  LEU   A CD1  1 
ATOM   202  C  CD1  B LEU   A 1 13  ? 36.26813 -5.76906  19.02435  0.300 54.43047  ? 13  LEU   A CD1  1 
ATOM   203  C  CD2  A LEU   A 1 13  ? 36.57499 -5.65718  19.26690  0.700 59.51042  ? 13  LEU   A CD2  1 
ATOM   204  C  CD2  B LEU   A 1 13  ? 36.42991 -8.27109  18.95192  0.300 38.47375  ? 13  LEU   A CD2  1 
ATOM   205  H  H    A LEU   A 1 13  ? 36.84869 -5.36514  15.57047  0.700 77.07994  ? 13  LEU   A H    1 
ATOM   206  H  H    B LEU   A 1 13  ? 36.84681 -5.36170  15.56872  0.300 77.07994  ? 13  LEU   A H    1 
ATOM   207  H  HA   A LEU   A 1 13  ? 38.50214 -4.95856  17.67159  0.700 46.83305  ? 13  LEU   A HA   1 
ATOM   208  H  HA   B LEU   A 1 13  ? 38.49136 -4.99745  17.68130  0.300 47.34897  ? 13  LEU   A HA   1 
ATOM   209  H  HB2  A LEU   A 1 13  ? 37.61964 -7.43912  16.66940  0.700 44.95402  ? 13  LEU   A HB2  1 
ATOM   210  H  HB2  B LEU   A 1 13  ? 37.12673 -7.21892  16.76071  0.300 45.66717  ? 13  LEU   A HB2  1 
ATOM   211  H  HB3  A LEU   A 1 13  ? 38.51308 -7.25389  17.97050  0.700 44.95402  ? 13  LEU   A HB3  1 
ATOM   212  H  HB3  B LEU   A 1 13  ? 38.56060 -7.50386  17.38380  0.300 45.66717  ? 13  LEU   A HB3  1 
ATOM   213  H  HG   A LEU   A 1 13  ? 35.76720 -6.68496  17.72757  0.700 52.13790  ? 13  LEU   A HG   1 
ATOM   214  H  HG   B LEU   A 1 13  ? 37.88709 -6.91011  19.44437  0.300 69.79826  ? 13  LEU   A HG   1 
ATOM   215  H  HD11 A LEU   A 1 13  ? 35.57152 -8.15505  19.52196  0.700 46.68846  ? 13  LEU   A HD11 1 
ATOM   216  H  HD11 B LEU   A 1 13  ? 35.71276 -5.95270  19.79814  0.300 65.33083  ? 13  LEU   A HD11 1 
ATOM   217  H  HD12 A LEU   A 1 13  ? 36.38664 -8.87481  18.36393  0.700 46.68846  ? 13  LEU   A HD12 1 
ATOM   218  H  HD12 B LEU   A 1 13  ? 36.81008 -4.98093  19.18572  0.300 65.33083  ? 13  LEU   A HD12 1 
ATOM   219  H  HD13 A LEU   A 1 13  ? 37.15266 -8.27361  19.61904  0.700 46.68846  ? 13  LEU   A HD13 1 
ATOM   220  H  HD13 B LEU   A 1 13  ? 35.71094 -5.63287  18.24211  0.300 65.33083  ? 13  LEU   A HD13 1 
ATOM   221  H  HD21 A LEU   A 1 13  ? 35.92730 -5.81780  19.97089  0.700 71.42677  ? 13  LEU   A HD21 1 
ATOM   222  H  HD21 B LEU   A 1 13  ? 36.10621 -8.33235  19.86426  0.300 46.18277  ? 13  LEU   A HD21 1 
ATOM   223  H  HD22 A LEU   A 1 13  ? 37.46489 -5.58565  19.64619  0.700 71.42677  ? 13  LEU   A HD22 1 
ATOM   224  H  HD22 B LEU   A 1 13  ? 35.68264 -8.29082  18.33378  0.300 46.18277  ? 13  LEU   A HD22 1 
ATOM   225  H  HD23 A LEU   A 1 13  ? 36.35148 -4.84171  18.79156  0.700 71.42677  ? 13  LEU   A HD23 1 
ATOM   226  H  HD23 B LEU   A 1 13  ? 37.03339 -9.00712  18.76492  0.300 46.18277  ? 13  LEU   A HD23 1 
ATOM   227  N  N    . ILE   A 1 14  ? 39.60112 -5.17402  14.87303  1.000 43.78356  ? 14  ILE   A N    1 
ATOM   228  C  CA   . ILE   A 1 14  ? 40.79489 -5.20586  14.04456  1.000 33.73846  ? 14  ILE   A CA   1 
ATOM   229  C  C    . ILE   A 1 14  ? 41.61158 -3.96512  14.35936  1.000 38.88417  ? 14  ILE   A C    1 
ATOM   230  O  O    . ILE   A 1 14  ? 41.06504 -2.85384  14.44737  1.000 37.57929  ? 14  ILE   A O    1 
ATOM   231  C  CB   . ILE   A 1 14  ? 40.42591 -5.26754  12.54692  1.000 39.32983  ? 14  ILE   A CB   1 
ATOM   232  C  CG1  . ILE   A 1 14  ? 39.54297 -6.47951  12.25989  1.000 43.85075  ? 14  ILE   A CG1  1 
ATOM   233  C  CG2  . ILE   A 1 14  ? 41.68414 -5.29052  11.69216  1.000 39.25832  ? 14  ILE   A CG2  1 
ATOM   234  C  CD1  . ILE   A 1 14  ? 40.23006 -7.81439  12.44531  1.000 46.13969  ? 14  ILE   A CD1  1 
ATOM   235  H  H    . ILE   A 1 14  ? 38.93547 -4.77740  14.49994  1.000 52.55454  ? 14  ILE   A H    1 
ATOM   236  H  HA   . ILE   A 1 14  ? 41.31908 -5.99500  14.25283  1.000 40.50042  ? 14  ILE   A HA   1 
ATOM   237  H  HB   . ILE   A 1 14  ? 39.92025 -4.47095  12.32188  1.000 47.21006  ? 14  ILE   A HB   1 
ATOM   238  H  HG12 . ILE   A 1 14  ? 38.78149 -6.45618  12.86032  1.000 52.63518  ? 14  ILE   A HG12 1 
ATOM   239  H  HG13 . ILE   A 1 14  ? 39.24118 -6.43085  11.33931  1.000 52.63518  ? 14  ILE   A HG13 1 
ATOM   240  H  HG21 . ILE   A 1 14  ? 41.43663 -5.46386  10.77043  1.000 47.12426  ? 14  ILE   A HG21 1 
ATOM   241  H  HG22 . ILE   A 1 14  ? 42.12740 -4.43035  11.75947  1.000 47.12426  ? 14  ILE   A HG22 1 
ATOM   242  H  HG23 . ILE   A 1 14  ? 42.27198 -5.99166  12.01427  1.000 47.12426  ? 14  ILE   A HG23 1 
ATOM   243  H  HD11 . ILE   A 1 14  ? 39.59543 -8.52450  12.26122  1.000 55.38190  ? 14  ILE   A HD11 1 
ATOM   244  H  HD12 . ILE   A 1 14  ? 40.97860 -7.87230  11.83111  1.000 55.38190  ? 14  ILE   A HD12 1 
ATOM   245  H  HD13 . ILE   A 1 14  ? 40.54646 -7.88239  13.35973  1.000 55.38190  ? 14  ILE   A HD13 1 
ATOM   246  N  N    . SER   A 1 15  ? 42.92233 -4.13934  14.51806  1.000 32.41367  ? 15  SER   A N    1 
ATOM   247  C  CA   . SER   A 1 15  ? 43.76658 -3.00152  14.86107  1.000 37.14127  ? 15  SER   A CA   1 
ATOM   248  C  C    . SER   A 1 15  ? 43.68248 -1.93351  13.77265  1.000 62.53769  ? 15  SER   A C    1 
ATOM   249  O  O    . SER   A 1 15  ? 43.44279 -2.22503  12.59476  1.000 40.19416  ? 15  SER   A O    1 
ATOM   250  C  CB   . SER   A 1 15  ? 45.21299 -3.44304  15.05289  1.000 53.48715  ? 15  SER   A CB   1 
ATOM   251  O  OG   . SER   A 1 15  ? 45.82200 -3.76601  13.82613  1.000 46.36538  ? 15  SER   A OG   1 
ATOM   252  H  H    . SER   A 1 15  ? 43.33631 -4.88850  14.43446  1.000 38.91068  ? 15  SER   A H    1 
ATOM   253  H  HA   . SER   A 1 15  ? 43.46203 -2.61448  15.69674  1.000 44.58379  ? 15  SER   A HA   1 
ATOM   254  H  HB2  . SER   A 1 15  ? 45.70863 -2.71955  15.46739  1.000 64.19886  ? 15  SER   A HB2  1 
ATOM   255  H  HB3  . SER   A 1 15  ? 45.22785 -4.22598  15.62532  1.000 64.19886  ? 15  SER   A HB3  1 
ATOM   256  H  HG   . SER   A 1 15  ? 46.63433 -3.94278  13.94639  1.000 55.65273  ? 15  SER   A HG   1 
ATOM   257  N  N    . VAL   A 1 16  ? 43.88501 -0.67703  14.17335  1.000 67.03830  ? 16  VAL   A N    1 
ATOM   258  C  CA   . VAL   A 1 16  ? 43.80765 0.41540   13.20634  1.000 53.86811  ? 16  VAL   A CA   1 
ATOM   259  C  C    . VAL   A 1 16  ? 44.91108 0.27849   12.16371  1.000 44.81424  ? 16  VAL   A C    1 
ATOM   260  O  O    . VAL   A 1 16  ? 44.67279 0.44860   10.96251  1.000 52.63496  ? 16  VAL   A O    1 
ATOM   261  C  CB   . VAL   A 1 16  ? 43.86253 1.77398   13.92930  1.000 77.60601  ? 16  VAL   A CB   1 
ATOM   262  C  CG1  . VAL   A 1 16  ? 42.77371 1.84590   14.99523  1.000 76.66840  ? 16  VAL   A CG1  1 
ATOM   263  C  CG2  . VAL   A 1 16  ? 45.23031 2.00995   14.54365  1.000 75.59850  ? 16  VAL   A CG2  1 
ATOM   264  H  H    . VAL   A 1 16  ? 44.06428 -0.43691  14.97945  1.000 80.46023  ? 16  VAL   A H    1 
ATOM   265  H  HA   . VAL   A 1 16  ? 42.95651 0.36241   12.74411  1.000 64.65600  ? 16  VAL   A HA   1 
ATOM   266  H  HB   . VAL   A 1 16  ? 43.70689 2.47856   13.28104  1.000 93.14148  ? 16  VAL   A HB   1 
ATOM   267  H  HG11 . VAL   A 1 16  ? 42.76368 2.73766   15.37676  1.000 92.01635  ? 16  VAL   A HG11 1 
ATOM   268  H  HG12 . VAL   A 1 16  ? 41.91652 1.65213   14.58464  1.000 92.01635  ? 16  VAL   A HG12 1 
ATOM   269  H  HG13 . VAL   A 1 16  ? 42.96468 1.19257   15.68631  1.000 92.01635  ? 16  VAL   A HG13 1 
ATOM   270  H  HG21 . VAL   A 1 16  ? 45.18014 2.77066   15.14340  1.000 90.73247  ? 16  VAL   A HG21 1 
ATOM   271  H  HG22 . VAL   A 1 16  ? 45.49636 1.21761   15.03591  1.000 90.73247  ? 16  VAL   A HG22 1 
ATOM   272  H  HG23 . VAL   A 1 16  ? 45.86815 2.18886   13.83509  1.000 90.73247  ? 16  VAL   A HG23 1 
ATOM   273  N  N    . GLU   A 1 17  ? 46.12745 -0.05036  12.60140  1.000 41.80099  ? 17  GLU   A N    1 
ATOM   274  C  CA   . GLU   A 1 17  ? 47.21050 -0.28452  11.65460  1.000 62.50260  ? 17  GLU   A CA   1 
ATOM   275  C  C    . GLU   A 1 17  ? 46.88425 -1.45114  10.73186  1.000 53.46772  ? 17  GLU   A C    1 
ATOM   276  O  O    . GLU   A 1 17  ? 47.15373 -1.39360  9.52965   1.000 39.91529  ? 17  GLU   A O    1 
ATOM   277  C  CB   . GLU   A 1 17  ? 48.52330 -0.56152  12.39197  1.000 66.17075  ? 17  GLU   A CB   1 
ATOM   278  C  CG   . GLU   A 1 17  ? 49.08711 0.61248   13.18732  1.000 88.77416  ? 17  GLU   A CG   1 
ATOM   279  C  CD   . GLU   A 1 17  ? 48.35269 0.85158   14.49495  1.000 100.16146 ? 17  GLU   A CD   1 
ATOM   280  O  OE1  . GLU   A 1 17  ? 48.10147 2.03184   14.82551  1.000 69.60199  ? 17  GLU   A OE1  1 
ATOM   281  O  OE2  . GLU   A 1 17  ? 48.02259 -0.14485  15.18614  1.000 54.91416  ? 17  GLU   A OE2  1 
ATOM   282  H  H    . GLU   A 1 17  ? 46.34627 -0.14234  13.42799  1.000 50.17546  ? 17  GLU   A H    1 
ATOM   283  H  HA   . GLU   A 1 17  ? 47.32710 0.51765   11.12185  1.000 75.01739  ? 17  GLU   A HA   1 
ATOM   284  H  HB2  . GLU   A 1 17  ? 48.37546 -1.28922  13.01607  1.000 79.41918  ? 17  GLU   A HB2  1 
ATOM   285  H  HB3  . GLU   A 1 17  ? 49.19307 -0.81612  11.73815  1.000 79.41918  ? 17  GLU   A HB3  1 
ATOM   286  H  HG2  . GLU   A 1 17  ? 50.01756 0.43412   13.39552  1.000 106.54326 ? 17  GLU   A HG2  1 
ATOM   287  H  HG3  . GLU   A 1 17  ? 49.01542 1.41864   12.65266  1.000 106.54326 ? 17  GLU   A HG3  1 
ATOM   288  N  N    . GLY   A 1 18  ? 46.30157 -2.51938  11.28091  1.000 38.01651  ? 18  GLY   A N    1 
ATOM   289  C  CA   . GLY   A 1 18  ? 46.04112 -3.70415  10.48175  1.000 38.52886  ? 18  GLY   A CA   1 
ATOM   290  C  C    . GLY   A 1 18  ? 45.00011 -3.45626  9.40846   1.000 40.79063  ? 18  GLY   A C    1 
ATOM   291  O  O    . GLY   A 1 18  ? 45.18436 -3.85739  8.25425   1.000 32.08121  ? 18  GLY   A O    1 
ATOM   292  H  H    . GLY   A 1 18  ? 46.05266 -2.57857  12.10197  1.000 45.63409  ? 18  GLY   A H    1 
ATOM   293  H  HA2  . GLY   A 1 18  ? 46.86261 -3.98860  10.05149  1.000 46.24890  ? 18  GLY   A HA2  1 
ATOM   294  H  HA3  . GLY   A 1 18  ? 45.72313 -4.41687  11.05777  1.000 46.24890  ? 18  GLY   A HA3  1 
ATOM   295  N  N    . ALA   A 1 19  ? 43.88605 -2.80817  9.77493   1.000 33.41346  ? 19  ALA   A N    1 
ATOM   296  C  CA   . ALA   A 1 19  ? 42.83015 -2.54608  8.80096   1.000 37.91460  ? 19  ALA   A CA   1 
ATOM   297  C  C    . ALA   A 1 19  ? 43.33526 -1.65422  7.67019   1.000 29.72574  ? 19  ALA   A C    1 
ATOM   298  O  O    . ALA   A 1 19  ? 43.09676 -1.92883  6.48308   1.000 32.05869  ? 19  ALA   A O    1 
ATOM   299  C  CB   . ALA   A 1 19  ? 41.63110 -1.90287  9.48962   1.000 45.04454  ? 19  ALA   A CB   1 
ATOM   300  H  H    . ALA   A 1 19  ? 43.72369 -2.51670  10.56758  1.000 40.11042  ? 19  ALA   A H    1 
ATOM   301  H  HA   . ALA   A 1 19  ? 42.54420 -3.39032  8.41836   1.000 45.51179  ? 19  ALA   A HA   1 
ATOM   302  H  HB1  . ALA   A 1 19  ? 40.94479 -1.72479  8.82768   1.000 54.06772  ? 19  ALA   A HB1  1 
ATOM   303  H  HB2  . ALA   A 1 19  ? 41.29039 -2.51123  10.16394  1.000 54.06772  ? 19  ALA   A HB2  1 
ATOM   304  H  HB3  . ALA   A 1 19  ? 41.91324 -1.07299  9.90507   1.000 54.06772  ? 19  ALA   A HB3  1 
ATOM   305  N  N    . TYR   A 1 20  ? 44.05004 -0.58007  8.02049   1.000 35.33315  ? 20  TYR   A N    1 
ATOM   306  C  CA   . TYR   A 1 20  ? 44.59900 0.30025   6.99188   1.000 34.55632  ? 20  TYR   A CA   1 
ATOM   307  C  C    . TYR   A 1 20  ? 45.58479 -0.44276  6.10499   1.000 35.55545  ? 20  TYR   A C    1 
ATOM   308  O  O    . TYR   A 1 20  ? 45.57885 -0.27248  4.87445   1.000 32.32654  ? 20  TYR   A O    1 
ATOM   309  C  CB   . TYR   A 1 20  ? 45.26784 1.51493   7.63740   1.000 37.08187  ? 20  TYR   A CB   1 
ATOM   310  C  CG   . TYR   A 1 20  ? 45.81417 2.50494   6.62137   1.000 36.15867  ? 20  TYR   A CG   1 
ATOM   311  C  CD1  . TYR   A 1 20  ? 44.99583 3.45846   6.05015   1.000 36.13958  ? 20  TYR   A CD1  1 
ATOM   312  C  CD2  . TYR   A 1 20  ? 47.14183 2.46548   6.24012   1.000 33.14803  ? 20  TYR   A CD2  1 
ATOM   313  C  CE1  . TYR   A 1 20  ? 45.48717 4.35858   5.12269   1.000 40.18950  ? 20  TYR   A CE1  1 
ATOM   314  C  CE2  . TYR   A 1 20  ? 47.63994 3.36022   5.30802   1.000 36.01269  ? 20  TYR   A CE2  1 
ATOM   315  C  CZ   . TYR   A 1 20  ? 46.80051 4.29934   4.75576   1.000 36.66905  ? 20  TYR   A CZ   1 
ATOM   316  O  OH   . TYR   A 1 20  ? 47.29373 5.19066   3.81983   1.000 44.24639  ? 20  TYR   A OH   1 
ATOM   317  H  H    . TYR   A 1 20  ? 44.22659 -0.34558  8.82885   1.000 42.41405  ? 20  TYR   A H    1 
ATOM   318  H  HA   . TYR   A 1 20  ? 43.87228 0.62074   6.43504   1.000 41.48185  ? 20  TYR   A HA   1 
ATOM   319  H  HB2  . TYR   A 1 20  ? 44.61566 1.97856   8.18569   1.000 44.51252  ? 20  TYR   A HB2  1 
ATOM   320  H  HB3  . TYR   A 1 20  ? 46.00749 1.21160   8.18677   1.000 44.51252  ? 20  TYR   A HB3  1 
ATOM   321  H  HD1  . TYR   A 1 20  ? 44.09893 3.49613   6.29317   1.000 43.38177  ? 20  TYR   A HD1  1 
ATOM   322  H  HD2  . TYR   A 1 20  ? 47.70813 1.82978   6.61439   1.000 39.79190  ? 20  TYR   A HD2  1 
ATOM   323  H  HE1  . TYR   A 1 20  ? 44.92615 5.00052   4.75111   1.000 48.24167  ? 20  TYR   A HE1  1 
ATOM   324  H  HE2  . TYR   A 1 20  ? 48.53491 3.32639   5.05746   1.000 43.22950  ? 20  TYR   A HE2  1 
ATOM   325  H  HH   . TYR   A 1 20  ? 48.09548 5.01024   3.64589   1.000 53.10994  ? 20  TYR   A HH   1 
ATOM   326  N  N    . LYS   A 1 21  ? 46.42634 -1.28527  6.70050   1.000 33.23727  ? 21  LYS   A N    1 
ATOM   327  C  CA   . LYS   A 1 21  ? 47.41780 -2.01528  5.91512   1.000 38.43102  ? 21  LYS   A CA   1 
ATOM   328  C  C    . LYS   A 1 21  ? 46.76231 -2.99192  4.94518   1.000 34.10000  ? 21  LYS   A C    1 
ATOM   329  O  O    . LYS   A 1 21  ? 47.19097 -3.10339  3.79352   1.000 32.85516  ? 21  LYS   A O    1 
ATOM   330  C  CB   . LYS   A 1 21  ? 48.38321 -2.75525  6.83946   1.000 37.49577  ? 21  LYS   A CB   1 
ATOM   331  C  CG   . LYS   A 1 21  ? 49.53476 -3.44038  6.11053   1.000 43.96240  ? 21  LYS   A CG   1 
ATOM   332  C  CD   . LYS   A 1 21  ? 50.61681 -3.91708  7.08388   1.000 52.13426  ? 21  LYS   A CD   1 
ATOM   333  C  CE   . LYS   A 1 21  ? 52.00217 -3.91312  6.43844   1.000 63.63191  ? 21  LYS   A CE   1 
ATOM   334  N  NZ   . LYS   A 1 21  ? 52.36337 -5.22365  5.83759   1.000 88.71448  ? 21  LYS   A NZ   1 
ATOM   335  H  H    . LYS   A 1 21  ? 46.44442 -1.45012  7.54436   1.000 39.89899  ? 21  LYS   A H    1 
ATOM   336  H  HA   . LYS   A 1 21  ? 47.92569 -1.37283  5.39530   1.000 46.13149  ? 21  LYS   A HA   1 
ATOM   337  H  HB2  . LYS   A 1 21  ? 48.76562 -2.11892  7.46375   1.000 45.00920  ? 21  LYS   A HB2  1 
ATOM   338  H  HB3  . LYS   A 1 21  ? 47.89080 -3.43796  7.32149   1.000 45.00920  ? 21  LYS   A HB3  1 
ATOM   339  H  HG2  . LYS   A 1 21  ? 49.19627 -4.21223  5.63035   1.000 52.76915  ? 21  LYS   A HG2  1 
ATOM   340  H  HG3  . LYS   A 1 21  ? 49.93883 -2.81430  5.48952   1.000 52.76915  ? 21  LYS   A HG3  1 
ATOM   341  H  HD2  . LYS   A 1 21  ? 50.63847 -3.32633  7.85293   1.000 62.57538  ? 21  LYS   A HD2  1 
ATOM   342  H  HD3  . LYS   A 1 21  ? 50.41631 -4.82294  7.36693   1.000 62.57538  ? 21  LYS   A HD3  1 
ATOM   343  H  HE2  . LYS   A 1 21  ? 52.02078 -3.24595  5.73458   1.000 76.37256  ? 21  LYS   A HE2  1 
ATOM   344  H  HE3  . LYS   A 1 21  ? 52.66487 -3.70098  7.11425   1.000 76.37256  ? 21  LYS   A HE3  1 
ATOM   345  H  HZ1  . LYS   A 1 21  ? 53.15385 -5.16541  5.43281   1.000 106.47165 ? 21  LYS   A HZ1  1 
ATOM   346  H  HZ2  . LYS   A 1 21  ? 52.40858 -5.84694  6.47128   1.000 106.47165 ? 21  LYS   A HZ2  1 
ATOM   347  H  HZ3  . LYS   A 1 21  ? 51.74960 -5.46382  5.23950   1.000 106.47165 ? 21  LYS   A HZ3  1 
ATOM   348  N  N    . VAL   A 1 22  ? 45.73957 -3.72486  5.39199   1.000 31.83541  ? 22  VAL   A N    1 
ATOM   349  C  CA   . VAL   A 1 22  ? 44.99840 -4.58475  4.46678   1.000 33.41546  ? 22  VAL   A CA   1 
ATOM   350  C  C    . VAL   A 1 22  ? 44.50709 -3.77016  3.27774   1.000 30.64360  ? 22  VAL   A C    1 
ATOM   351  O  O    . VAL   A 1 22  ? 44.71581 -4.13870  2.11069   1.000 31.24579  ? 22  VAL   A O    1 
ATOM   352  C  CB   . VAL   A 1 22  ? 43.83287 -5.27876  5.19431   1.000 35.17524  ? 22  VAL   A CB   1 
ATOM   353  C  CG1  . VAL   A 1 22  ? 42.92248 -6.02525  4.20183   1.000 31.17421  ? 22  VAL   A CG1  1 
ATOM   354  C  CG2  . VAL   A 1 22  ? 44.36354 -6.24783  6.27106   1.000 33.98297  ? 22  VAL   A CG2  1 
ATOM   355  H  H    . VAL   A 1 22  ? 45.46134 -3.74212  6.20555   1.000 38.21677  ? 22  VAL   A H    1 
ATOM   356  H  HA   . VAL   A 1 22  ? 45.59561 -5.27365  4.13563   1.000 40.11282  ? 22  VAL   A HA   1 
ATOM   357  H  HB   . VAL   A 1 22  ? 43.29965 -4.59660  5.63162   1.000 42.22456  ? 22  VAL   A HB   1 
ATOM   358  H  HG11 . VAL   A 1 22  ? 42.31388 -6.59449  4.69829   1.000 37.42333  ? 22  VAL   A HG11 1 
ATOM   359  H  HG12 . VAL   A 1 22  ? 42.42054 -5.37636  3.68423   1.000 37.42333  ? 22  VAL   A HG12 1 
ATOM   360  H  HG13 . VAL   A 1 22  ? 43.47289 -6.56418  3.61234   1.000 37.42333  ? 22  VAL   A HG13 1 
ATOM   361  H  HG21 . VAL   A 1 22  ? 43.61316 -6.60830  6.76894   1.000 40.79384  ? 22  VAL   A HG21 1 
ATOM   362  H  HG22 . VAL   A 1 22  ? 44.84871 -6.96703  5.83715   1.000 40.79384  ? 22  VAL   A HG22 1 
ATOM   363  H  HG23 . VAL   A 1 22  ? 44.95464 -5.76328  6.86831   1.000 40.79384  ? 22  VAL   A HG23 1 
ATOM   364  N  N    . ARG   A 1 23  ? 43.84592 -2.64542  3.55797   1.000 28.38896  ? 23  ARG   A N    1 
ATOM   365  C  CA   . ARG   A 1 23  ? 43.28072 -1.82219  2.50127   1.000 30.16631  ? 23  ARG   A CA   1 
ATOM   366  C  C    . ARG   A 1 23  ? 44.37121 -1.28092  1.58484   1.000 28.07107  ? 23  ARG   A C    1 
ATOM   367  O  O    . ARG   A 1 23  ? 44.25232 -1.32606  0.35261   1.000 29.40838  ? 23  ARG   A O    1 
ATOM   368  C  CB   . ARG   A 1 23  ? 42.48127 -0.67517  3.11519   1.000 30.50451  ? 23  ARG   A CB   1 
ATOM   369  C  CG   . ARG   A 1 23  ? 41.13357 -1.05676  3.69342   1.000 40.18413  ? 23  ARG   A CG   1 
ATOM   370  C  CD   . ARG   A 1 23  ? 40.65501 0.04805   4.64607   1.000 45.81157  ? 23  ARG   A CD   1 
ATOM   371  N  NE   . ARG   A 1 23  ? 39.25366 -0.07611  5.01373   1.000 59.95037  ? 23  ARG   A NE   1 
ATOM   372  C  CZ   . ARG   A 1 23  ? 38.79259 -0.90556  5.93836   1.000 68.08723  ? 23  ARG   A CZ   1 
ATOM   373  N  NH1  . ARG   A 1 23  ? 39.59237 -1.75570  6.56335   1.000 64.19905  ? 23  ARG   A NH1  1 
ATOM   374  N  NH2  . ARG   A 1 23  ? 37.49699 -0.88014  6.24506   1.000 57.94157  ? 23  ARG   A NH2  1 
ATOM   375  H  H    . ARG   A 1 23  ? 43.71317 -2.34097  4.35124   1.000 34.08103  ? 23  ARG   A H    1 
ATOM   376  H  HA   . ARG   A 1 23  ? 42.67974 -2.36451  1.96685   1.000 36.21384  ? 23  ARG   A HA   1 
ATOM   377  H  HB2  . ARG   A 1 23  ? 43.00513 -0.28867  3.83428   1.000 36.61969  ? 23  ARG   A HB2  1 
ATOM   378  H  HB3  . ARG   A 1 23  ? 42.32242 -0.01095  2.42637   1.000 36.61969  ? 23  ARG   A HB3  1 
ATOM   379  H  HG2  . ARG   A 1 23  ? 40.48532 -1.15705  2.97885   1.000 48.23522  ? 23  ARG   A HG2  1 
ATOM   380  H  HG3  . ARG   A 1 23  ? 41.21138 -1.88658  4.18965   1.000 48.23522  ? 23  ARG   A HG3  1 
ATOM   381  H  HD2  . ARG   A 1 23  ? 41.18059 0.01001   5.46045   1.000 54.98815  ? 23  ARG   A HD2  1 
ATOM   382  H  HD3  . ARG   A 1 23  ? 40.77404 0.90845   4.21428   1.000 54.98815  ? 23  ARG   A HD3  1 
ATOM   383  H  HE   . ARG   A 1 23  ? 38.68576 0.42253   4.60330   1.000 71.95471  ? 23  ARG   A HE   1 
ATOM   384  H  HH11 . ARG   A 1 23  ? 40.43053 -1.77752  6.37203   1.000 77.05313  ? 23  ARG   A HH11 1 
ATOM   385  H  HH12 . ARG   A 1 23  ? 39.27370 -2.28608  7.16064   1.000 77.05313  ? 23  ARG   A HH12 1 
ATOM   386  H  HH21 . ARG   A 1 23  ? 36.97102 -0.33004  5.84462   1.000 69.54416  ? 23  ARG   A HH21 1 
ATOM   387  H  HH22 . ARG   A 1 23  ? 37.18623 -1.41382  6.84358   1.000 69.54416  ? 23  ARG   A HH22 1 
ATOM   388  N  N    . LEU   A 1 24  ? 45.45146 -0.77241  2.16582   1.000 30.56331  ? 24  LEU   A N    1 
ATOM   389  C  CA   . LEU   A 1 24  ? 46.53556 -0.24064  1.34935   1.000 34.42144  ? 24  LEU   A CA   1 
ATOM   390  C  C    . LEU   A 1 24  ? 47.12225 -1.32167  0.44791   1.000 31.58998  ? 24  LEU   A C    1 
ATOM   391  O  O    . LEU   A 1 24  ? 47.40947 -1.07571  -0.73001  1.000 30.30123  ? 24  LEU   A O    1 
ATOM   392  C  CB   . LEU   A 1 24  ? 47.61818 0.34850   2.23826   1.000 30.42697  ? 24  LEU   A CB   1 
ATOM   393  C  CG   . LEU   A 1 24  ? 48.68503 1.13935   1.47163   1.000 34.21129  ? 24  LEU   A CG   1 
ATOM   394  C  CD1  . LEU   A 1 24  ? 48.06911 2.32792   0.73783   1.000 34.55655  ? 24  LEU   A CD1  1 
ATOM   395  C  CD2  . LEU   A 1 24  ? 49.79657 1.58926   2.41376   1.000 38.45577  ? 24  LEU   A CD2  1 
ATOM   396  H  H    . LEU   A 1 24  ? 45.58025 -0.72373  3.01473   1.000 36.69024  ? 24  LEU   A H    1 
ATOM   397  H  HA   . LEU   A 1 24  ? 46.18560 0.46913   0.78841   1.000 41.32000  ? 24  LEU   A HA   1 
ATOM   398  H  HB2  . LEU   A 1 24  ? 47.20366 0.95053   2.87593   1.000 36.52663  ? 24  LEU   A HB2  1 
ATOM   399  H  HB3  . LEU   A 1 24  ? 48.06412 -0.37470  2.70627   1.000 36.52663  ? 24  LEU   A HB3  1 
ATOM   400  H  HG   . LEU   A 1 24  ? 49.07973 0.56140   0.80000   1.000 41.06781  ? 24  LEU   A HG   1 
ATOM   401  H  HD11 . LEU   A 1 24  ? 48.77669 2.93523   0.47059   1.000 41.48213  ? 24  LEU   A HD11 1 
ATOM   402  H  HD12 . LEU   A 1 24  ? 47.59682 2.00516   -0.04554  1.000 41.48213  ? 24  LEU   A HD12 1 
ATOM   403  H  HD13 . LEU   A 1 24  ? 47.45158 2.78101   1.33304   1.000 41.48213  ? 24  LEU   A HD13 1 
ATOM   404  H  HD21 . LEU   A 1 24  ? 50.45681 2.08817   1.90772   1.000 46.16119  ? 24  LEU   A HD21 1 
ATOM   405  H  HD22 . LEU   A 1 24  ? 49.41551 2.15224   3.10567   1.000 46.16119  ? 24  LEU   A HD22 1 
ATOM   406  H  HD23 . LEU   A 1 24  ? 50.20796 0.80688   2.81319   1.000 46.16119  ? 24  LEU   A HD23 1 
ATOM   407  N  N    . LYS   A 1 25  ? 47.30377 -2.52920  0.98606   1.000 33.08713  ? 25  LYS   A N    1 
ATOM   408  C  CA   . LYS   A 1 25  ? 47.86226 -3.61643  0.19413   1.000 30.49273  ? 25  LYS   A CA   1 
ATOM   409  C  C    . LYS   A 1 25  ? 46.92387 -4.03601  -0.92484  1.000 30.15909  ? 25  LYS   A C    1 
ATOM   410  O  O    . LYS   A 1 25  ? 47.38837 -4.43515  -1.99973  1.000 29.56515  ? 25  LYS   A O    1 
ATOM   411  C  CB   . LYS   A 1 25  ? 48.19169 -4.79485  1.10450   1.000 30.09479  ? 25  LYS   A CB   1 
ATOM   412  C  CG   . LYS   A 1 25  ? 49.36085 -4.53773  2.03632   1.000 34.32955  ? 25  LYS   A CG   1 
ATOM   413  C  CD   . LYS   A 1 25  ? 50.67732 -4.70161  1.30620   1.000 42.93863  ? 25  LYS   A CD   1 
ATOM   414  C  CE   . LYS   A 1 25  ? 51.83664 -4.05287  2.06003   1.000 56.03028  ? 25  LYS   A CE   1 
ATOM   415  N  NZ   . LYS   A 1 25  ? 51.89281 -2.57378  1.81246   1.000 75.37377  ? 25  LYS   A NZ   1 
ATOM   416  H  H    . LYS   A 1 25  ? 47.11325 -2.73978  1.79782   1.000 39.71883  ? 25  LYS   A H    1 
ATOM   417  H  HA   . LYS   A 1 25  ? 48.68822 -3.32039  -0.21946  1.000 36.60554  ? 25  LYS   A HA   1 
ATOM   418  H  HB2  . LYS   A 1 25  ? 47.41529 -4.99342  1.65102   1.000 36.12802  ? 25  LYS   A HB2  1 
ATOM   419  H  HB3  . LYS   A 1 25  ? 48.41468 -5.56164  0.55386   1.000 36.12802  ? 25  LYS   A HB3  1 
ATOM   420  H  HG2  . LYS   A 1 25  ? 49.30934 -3.63141  2.37814   1.000 41.20973  ? 25  LYS   A HG2  1 
ATOM   421  H  HG3  . LYS   A 1 25  ? 49.33526 -5.17115  2.77050   1.000 41.20973  ? 25  LYS   A HG3  1 
ATOM   422  H  HD2  . LYS   A 1 25  ? 50.87196 -5.64674  1.20751   1.000 51.54062  ? 25  LYS   A HD2  1 
ATOM   423  H  HD3  . LYS   A 1 25  ? 50.61237 -4.28336  0.43341   1.000 51.54062  ? 25  LYS   A HD3  1 
ATOM   424  H  HE2  . LYS   A 1 25  ? 51.72262 -4.19890  3.01217   1.000 67.25061  ? 25  LYS   A HE2  1 
ATOM   425  H  HE3  . LYS   A 1 25  ? 52.67271 -4.44421  1.76214   1.000 67.25061  ? 25  LYS   A HE3  1 
ATOM   426  H  HZ1  . LYS   A 1 25  ? 52.57179 -2.21538  2.26261   1.000 90.46279  ? 25  LYS   A HZ1  1 
ATOM   427  H  HZ2  . LYS   A 1 25  ? 52.00584 -2.41456  0.94415   1.000 90.46279  ? 25  LYS   A HZ2  1 
ATOM   428  H  HZ3  . LYS   A 1 25  ? 51.13499 -2.19137  2.07999   1.000 90.46279  ? 25  LYS   A HZ3  1 
ATOM   429  N  N    . ILE   A 1 26  ? 45.61152 -3.93323  -0.71419  1.000 28.41425  ? 26  ILE   A N    1 
ATOM   430  C  CA   . ILE   A 1 26  ? 44.67670 -4.17637  -1.80730  1.000 33.67698  ? 26  ILE   A CA   1 
ATOM   431  C  C    . ILE   A 1 26  ? 44.89713 -3.15249  -2.91218  1.000 30.54837  ? 26  ILE   A C    1 
ATOM   432  O  O    . ILE   A 1 26  ? 45.01284 -3.49940  -4.10066  1.000 25.98388  ? 26  ILE   A O    1 
ATOM   433  C  CB   . ILE   A 1 26  ? 43.22991 -4.15654  -1.28149  1.000 27.78895  ? 26  ILE   A CB   1 
ATOM   434  C  CG1  . ILE   A 1 26  ? 42.99050 -5.34989  -0.33808  1.000 28.62505  ? 26  ILE   A CG1  1 
ATOM   435  C  CG2  . ILE   A 1 26  ? 42.22680 -4.20267  -2.44808  1.000 30.38550  ? 26  ILE   A CG2  1 
ATOM   436  C  CD1  . ILE   A 1 26  ? 41.63448 -5.34580  0.34396   1.000 32.82820  ? 26  ILE   A CD1  1 
ATOM   437  H  H    . ILE   A 1 26  ? 45.24572 -3.72844  0.03671   1.000 34.11137  ? 26  ILE   A H    1 
ATOM   438  H  HA   . ILE   A 1 26  ? 44.84203 -5.05641  -2.18026  1.000 40.42665  ? 26  ILE   A HA   1 
ATOM   439  H  HB   . ILE   A 1 26  ? 43.09908 -3.33070  -0.78979  1.000 33.36101  ? 26  ILE   A HB   1 
ATOM   440  H  HG12 . ILE   A 1 26  ? 43.05799 -6.16956  -0.85236  1.000 34.36433  ? 26  ILE   A HG12 1 
ATOM   441  H  HG13 . ILE   A 1 26  ? 43.66818 -5.33685  0.35581   1.000 34.36433  ? 26  ILE   A HG13 1 
ATOM   442  H  HG21 . ILE   A 1 26  ? 41.33025 -4.29724  -2.09010  1.000 36.47687  ? 26  ILE   A HG21 1 
ATOM   443  H  HG22 . ILE   A 1 26  ? 42.29501 -3.37909  -2.95597  1.000 36.47687  ? 26  ILE   A HG22 1 
ATOM   444  H  HG23 . ILE   A 1 26  ? 42.43774 -4.96007  -3.01618  1.000 36.47687  ? 26  ILE   A HG23 1 
ATOM   445  H  HD11 . ILE   A 1 26  ? 41.64355 -5.99046  1.06869   1.000 39.40811  ? 26  ILE   A HD11 1 
ATOM   446  H  HD12 . ILE   A 1 26  ? 41.45931 -4.45796  0.69319   1.000 39.40811  ? 26  ILE   A HD12 1 
ATOM   447  H  HD13 . ILE   A 1 26  ? 40.95420 -5.58642  -0.30428  1.000 39.40811  ? 26  ILE   A HD13 1 
ATOM   448  N  N    . MET   A 1 27  ? 44.97059 -1.86645  -2.53811  1.000 31.34070  ? 27  MET   A N    1 
ATOM   449  C  CA   . MET   A 1 27  ? 45.16065 -0.82856  -3.54260  1.000 29.45795  ? 27  MET   A CA   1 
ATOM   450  C  C    . MET   A 1 27  ? 46.46276 -1.02496  -4.30188  1.000 31.71651  ? 27  MET   A C    1 
ATOM   451  O  O    . MET   A 1 27  ? 46.50723 -0.84323  -5.51943  1.000 30.87901  ? 27  MET   A O    1 
ATOM   452  C  CB   . MET   A 1 27  ? 45.12941 0.55629   -2.91180  1.000 29.73918  ? 27  MET   A CB   1 
ATOM   453  C  CG   . MET   A 1 27  ? 43.76115 0.98904   -2.36697  1.000 31.69762  ? 27  MET   A CG   1 
ATOM   454  S  SD   . MET   A 1 27  ? 42.34642 0.44231   -3.28313  1.000 34.06738  ? 27  MET   A SD   1 
ATOM   455  C  CE   . MET   A 1 27  ? 41.32863 -0.29514  -2.03693  1.000 51.97435  ? 27  MET   A CE   1 
ATOM   456  H  H    . MET   A 1 27  ? 44.91407 -1.58197  -1.72849  1.000 37.62311  ? 27  MET   A H    1 
ATOM   457  H  HA   . MET   A 1 27  ? 44.41648 -0.88297  -4.16239  1.000 35.36381  ? 27  MET   A HA   1 
ATOM   458  H  HB2  . MET   A 1 27  ? 45.75540 0.57053   -2.17096  1.000 35.70128  ? 27  MET   A HB2  1 
ATOM   459  H  HB3  . MET   A 1 27  ? 45.39415 1.20528   -3.58235  1.000 35.70128  ? 27  MET   A HB3  1 
ATOM   460  H  HG2  . MET   A 1 27  ? 43.66987 0.64060   -1.46632  1.000 38.05141  ? 27  MET   A HG2  1 
ATOM   461  H  HG3  . MET   A 1 27  ? 43.73406 1.95854   -2.35194  1.000 38.05141  ? 27  MET   A HG3  1 
ATOM   462  H  HE1  . MET   A 1 27  ? 40.53764 -0.66910  -2.45571  1.000 62.38350  ? 27  MET   A HE1  1 
ATOM   463  H  HE2  . MET   A 1 27  ? 41.83087 -0.99640  -1.59320  1.000 62.38350  ? 27  MET   A HE2  1 
ATOM   464  H  HE3  . MET   A 1 27  ? 41.07260 0.38534   -1.39483  1.000 62.38350  ? 27  MET   A HE3  1 
ATOM   465  N  N    . GLU   A 1 28  ? 47.53385 -1.36008  -3.59541  1.000 30.28220  ? 28  GLU   A N    1 
ATOM   466  C  CA   . GLU   A 1 28  ? 48.81907 -1.58385  -4.24534  1.000 33.09297  ? 28  GLU   A CA   1 
ATOM   467  C  C    . GLU   A 1 28  ? 48.73360 -2.72009  -5.25408  1.000 33.22441  ? 28  GLU   A C    1 
ATOM   468  O  O    . GLU   A 1 28  ? 49.26835 -2.61407  -6.36618  1.000 30.99971  ? 28  GLU   A O    1 
ATOM   469  C  CB   . GLU   A 1 28  ? 49.89138 -1.88648  -3.19438  1.000 29.00950  ? 28  GLU   A CB   1 
ATOM   470  C  CG   . GLU   A 1 28  ? 50.29976 -0.68754  -2.36661  1.000 35.47647  ? 28  GLU   A CG   1 
ATOM   471  C  CD   . GLU   A 1 28  ? 51.27756 -1.05074  -1.25323  1.000 39.30034  ? 28  GLU   A CD   1 
ATOM   472  O  OE1  . GLU   A 1 28  ? 51.66119 -2.22598  -1.15162  1.000 38.64947  ? 28  GLU   A OE1  1 
ATOM   473  O  OE2  . GLU   A 1 28  ? 51.65588 -0.15580  -0.48707  1.000 38.76645  ? 28  GLU   A OE2  1 
ATOM   474  H  H    . GLU   A 1 28  ? 47.54539 -1.46444  -2.74184  1.000 36.35291  ? 28  GLU   A H    1 
ATOM   475  H  HA   . GLU   A 1 28  ? 49.07544 -0.77642  -4.71780  1.000 39.72583  ? 28  GLU   A HA   1 
ATOM   476  H  HB2  . GLU   A 1 28  ? 49.54951 -2.56131  -2.58723  1.000 34.82568  ? 28  GLU   A HB2  1 
ATOM   477  H  HB3  . GLU   A 1 28  ? 50.68391 -2.21702  -3.64553  1.000 34.82568  ? 28  GLU   A HB3  1 
ATOM   478  H  HG2  . GLU   A 1 28  ? 50.72875 -0.03585  -2.94294  1.000 42.58603  ? 28  GLU   A HG2  1 
ATOM   479  H  HG3  . GLU   A 1 28  ? 49.50959 -0.30027  -1.95849  1.000 42.58603  ? 28  GLU   A HG3  1 
ATOM   480  N  N    . GLU   A 1 29  ? 48.05693 -3.81292  -4.88620  1.000 32.52962  ? 29  GLU   A N    1 
ATOM   481  C  CA   . GLU   A 1 29  ? 47.88385 -4.93141  -5.80535  1.000 31.92952  ? 29  GLU   A CA   1 
ATOM   482  C  C    . GLU   A 1 29  ? 47.03060 -4.53514  -7.00784  1.000 29.83705  ? 29  GLU   A C    1 
ATOM   483  O  O    . GLU   A 1 29  ? 47.31977 -4.93511  -8.14200  1.000 31.78241  ? 29  GLU   A O    1 
ATOM   484  C  CB   . GLU   A 1 29  ? 47.26362 -6.11608  -5.05619  1.000 32.55121  ? 29  GLU   A CB   1 
ATOM   485  C  CG   . GLU   A 1 29  ? 47.06212 -7.35898  -5.92475  1.000 27.79723  ? 29  GLU   A CG   1 
ATOM   486  C  CD   . GLU   A 1 29  ? 48.37101 -7.88358  -6.47664  1.000 36.68798  ? 29  GLU   A CD   1 
ATOM   487  O  OE1  . GLU   A 1 29  ? 49.37131 -7.86457  -5.74031  1.000 41.32076  ? 29  GLU   A OE1  1 
ATOM   488  O  OE2  . GLU   A 1 29  ? 48.39225 -8.30057  -7.65326  1.000 40.72638  ? 29  GLU   A OE2  1 
ATOM   489  H  H    . GLU   A 1 29  ? 47.69245 -3.92775  -4.11577  1.000 39.04982  ? 29  GLU   A H    1 
ATOM   490  H  HA   . GLU   A 1 29  ? 48.75064 -5.20715  -6.14229  1.000 38.32969  ? 29  GLU   A HA   1 
ATOM   491  H  HB2  . GLU   A 1 29  ? 47.84769 -6.36021  -4.32123  1.000 39.07572  ? 29  GLU   A HB2  1 
ATOM   492  H  HB3  . GLU   A 1 29  ? 46.39549 -5.84925  -4.71551  1.000 39.07572  ? 29  GLU   A HB3  1 
ATOM   493  H  HG2  . GLU   A 1 29  ? 46.65610 -8.05925  -5.39028  1.000 33.37094  ? 29  GLU   A HG2  1 
ATOM   494  H  HG3  . GLU   A 1 29  ? 46.48569 -7.13574  -6.67228  1.000 33.37094  ? 29  GLU   A HG3  1 
ATOM   495  N  N    . VAL   A 1 30  ? 45.96757 -3.75594  -6.78522  1.000 31.96654  ? 30  VAL   A N    1 
ATOM   496  C  CA   . VAL   A 1 30  ? 45.10661 -3.34040  -7.88705  1.000 33.11862  ? 30  VAL   A CA   1 
ATOM   497  C  C    . VAL   A 1 30  ? 45.88128 -2.48960  -8.88565  1.000 29.88207  ? 30  VAL   A C    1 
ATOM   498  O  O    . VAL   A 1 30  ? 45.71753 -2.62578  -10.10645 1.000 29.60189  ? 30  VAL   A O    1 
ATOM   499  C  CB   . VAL   A 1 30  ? 43.87805 -2.59201  -7.34174  1.000 29.74648  ? 30  VAL   A CB   1 
ATOM   500  C  CG1  . VAL   A 1 30  ? 43.19194 -1.81732  -8.47323  1.000 28.24915  ? 30  VAL   A CG1  1 
ATOM   501  C  CG2  . VAL   A 1 30  ? 42.90247 -3.56842  -6.67884  1.000 30.78726  ? 30  VAL   A CG2  1 
ATOM   502  H  H    . VAL   A 1 30  ? 45.72845 -3.45944  -6.01418  1.000 38.37412  ? 30  VAL   A H    1 
ATOM   503  H  HA   . VAL   A 1 30  ? 44.79892 -4.13379  -8.35262  1.000 39.75662  ? 30  VAL   A HA   1 
ATOM   504  H  HB   . VAL   A 1 30  ? 44.16430 -1.95719  -6.66649  1.000 35.71004  ? 30  VAL   A HB   1 
ATOM   505  H  HG11 . VAL   A 1 30  ? 42.27891 -1.61956  -8.21215  1.000 33.91325  ? 30  VAL   A HG11 1 
ATOM   506  H  HG12 . VAL   A 1 30  ? 43.67710 -0.99222  -8.63047  1.000 33.91325  ? 30  VAL   A HG12 1 
ATOM   507  H  HG13 . VAL   A 1 30  ? 43.19587 -2.36152  -9.27618  1.000 33.91325  ? 30  VAL   A HG13 1 
ATOM   508  H  HG21 . VAL   A 1 30  ? 42.12061 -3.07887  -6.37895  1.000 36.95898  ? 30  VAL   A HG21 1 
ATOM   509  H  HG22 . VAL   A 1 30  ? 42.64242 -4.24294  -7.32560  1.000 36.95898  ? 30  VAL   A HG22 1 
ATOM   510  H  HG23 . VAL   A 1 30  ? 43.34075 -3.98760  -5.92180  1.000 36.95898  ? 30  VAL   A HG23 1 
ATOM   511  N  N    . LEU   A 1 31  ? 46.72575 -1.58945  -8.38741  1.000 29.80197  ? 31  LEU   A N    1 
ATOM   512  C  CA   . LEU   A 1 31  ? 47.38043 -0.61335  -9.24192  1.000 31.95001  ? 31  LEU   A CA   1 
ATOM   513  C  C    . LEU   A 1 31  ? 48.57573 -1.19794  -9.97732  1.000 33.52893  ? 31  LEU   A C    1 
ATOM   514  O  O    . LEU   A 1 31  ? 48.85613 -0.79645  -11.11401 1.000 31.28263  ? 31  LEU   A O    1 
ATOM   515  C  CB   . LEU   A 1 31  ? 47.82741 0.59219   -8.40362  1.000 30.24037  ? 31  LEU   A CB   1 
ATOM   516  C  CG   . LEU   A 1 31  ? 46.71034 1.53773   -7.96553  1.000 27.90818  ? 31  LEU   A CG   1 
ATOM   517  C  CD1  . LEU   A 1 31  ? 47.23899 2.54045   -6.95238  1.000 35.27712  ? 31  LEU   A CD1  1 
ATOM   518  C  CD2  . LEU   A 1 31  ? 46.07970 2.25855   -9.16717  1.000 31.09979  ? 31  LEU   A CD2  1 
ATOM   519  H  H    . LEU   A 1 31  ? 46.93519 -1.52499  -7.55580  1.000 35.77664  ? 31  LEU   A H    1 
ATOM   520  H  HA   . LEU   A 1 31  ? 46.74366 -0.30783  -9.90682  1.000 38.35428  ? 31  LEU   A HA   1 
ATOM   521  H  HB2  . LEU   A 1 31  ? 48.25845 0.26135   -7.60010  1.000 36.30272  ? 31  LEU   A HB2  1 
ATOM   522  H  HB3  . LEU   A 1 31  ? 48.45699 1.11123   -8.92815  1.000 36.30272  ? 31  LEU   A HB3  1 
ATOM   523  H  HG   . LEU   A 1 31  ? 46.00920 1.01561   -7.54516  1.000 33.50408  ? 31  LEU   A HG   1 
ATOM   524  H  HD11 . LEU   A 1 31  ? 46.52546 3.15165   -6.71109  1.000 42.34681  ? 31  LEU   A HD11 1 
ATOM   525  H  HD12 . LEU   A 1 31  ? 47.54556 2.06283   -6.16575  1.000 42.34681  ? 31  LEU   A HD12 1 
ATOM   526  H  HD13 . LEU   A 1 31  ? 47.97538 3.03173   -7.34896  1.000 42.34681  ? 31  LEU   A HD13 1 
ATOM   527  H  HD21 . LEU   A 1 31  ? 45.45469 2.92568   -8.84282  1.000 37.33402  ? 31  LEU   A HD21 1 
ATOM   528  H  HD22 . LEU   A 1 31  ? 46.78137 2.68576   -9.68299  1.000 37.33402  ? 31  LEU   A HD22 1 
ATOM   529  H  HD23 . LEU   A 1 31  ? 45.61424 1.60864   -9.71659  1.000 37.33402  ? 31  LEU   A HD23 1 
ATOM   530  N  N    . GLY   A 1 32  ? 49.28363 -2.14034  -9.36988  1.000 37.11940  ? 32  GLY   A N    1 
ATOM   531  C  CA   . GLY   A 1 32  ? 50.51750 -2.61290  -9.98271  1.000 40.87394  ? 32  GLY   A CA   1 
ATOM   532  C  C    . GLY   A 1 32  ? 51.46249 -1.44716  -10.19386 1.000 36.81243  ? 32  GLY   A C    1 
ATOM   533  O  O    . GLY   A 1 32  ? 51.75166 -0.67524  -9.27773  1.000 35.12629  ? 32  GLY   A O    1 
ATOM   534  H  H    . GLY   A 1 32  ? 49.07883 -2.51369  -8.62271  1.000 44.55755  ? 32  GLY   A H    1 
ATOM   535  H  HA2  . GLY   A 1 32  ? 50.94469 -3.26650  -9.40719  1.000 49.06300  ? 32  GLY   A HA2  1 
ATOM   536  H  HA3  . GLY   A 1 32  ? 50.32582 -3.02434  -10.83995 1.000 49.06300  ? 32  GLY   A HA3  1 
ATOM   537  N  N    . ASP   A 1 33  ? 51.92160 -1.28236  -11.43388 1.000 37.04406  ? 33  ASP   A N    1 
ATOM   538  C  CA   . ASP   A 1 33  ? 52.84596 -0.20671  -11.76611 1.000 40.32900  ? 33  ASP   A CA   1 
ATOM   539  C  C    . ASP   A 1 33  ? 52.14750 1.07411   -12.20546 1.000 35.22383  ? 33  ASP   A C    1 
ATOM   540  O  O    . ASP   A 1 33  ? 52.82707 2.03652   -12.57658 1.000 36.20949  ? 33  ASP   A O    1 
ATOM   541  C  CB   . ASP   A 1 33  ? 53.80061 -0.66343  -12.87912 1.000 45.61057  ? 33  ASP   A CB   1 
ATOM   542  C  CG   . ASP   A 1 33  ? 54.78606 -1.71282  -12.40726 1.000 48.84283  ? 33  ASP   A CG   1 
ATOM   543  O  OD1  . ASP   A 1 33  ? 55.15249 -1.68557  -11.21482 1.000 52.42073  ? 33  ASP   A OD1  1 
ATOM   544  O  OD2  . ASP   A 1 33  ? 55.19167 -2.56443  -13.23408 1.000 60.41369  ? 33  ASP   A OD2  1 
ATOM   545  H  H    . ASP   A 1 33  ? 51.70996 -1.78365  -12.09985 1.000 44.46714  ? 33  ASP   A H    1 
ATOM   546  H  HA   . ASP   A 1 33  ? 53.36935 -0.00203  -10.97549 1.000 48.40907  ? 33  ASP   A HA   1 
ATOM   547  H  HB2  . ASP   A 1 33  ? 53.28167 -1.04342  -13.60521 1.000 54.74696  ? 33  ASP   A HB2  1 
ATOM   548  H  HB3  . ASP   A 1 33  ? 54.30537 0.10148   -13.19697 1.000 54.74696  ? 33  ASP   A HB3  1 
ATOM   549  N  N    . TYR   A 1 34  ? 50.82515 1.11106   -12.20464 1.000 31.83658  ? 34  TYR   A N    1 
ATOM   550  C  CA   . TYR   A 1 34  ? 50.13013 2.31781   -12.63397 1.000 35.87048  ? 34  TYR   A CA   1 
ATOM   551  C  C    . TYR   A 1 34  ? 50.57866 3.49352   -11.76888 1.000 32.48486  ? 34  TYR   A C    1 
ATOM   552  O  O    . TYR   A 1 34  ? 50.70096 3.35804   -10.54517 1.000 35.01871  ? 34  TYR   A O    1 
ATOM   553  C  CB   . TYR   A 1 34  ? 48.61897 2.11523   -12.55304 1.000 35.45861  ? 34  TYR   A CB   1 
ATOM   554  C  CG   . TYR   A 1 34  ? 47.80024 3.11765   -13.33723 1.000 33.00651  ? 34  TYR   A CG   1 
ATOM   555  C  CD1  . TYR   A 1 34  ? 47.54457 2.92793   -14.68894 1.000 32.65483  ? 34  TYR   A CD1  1 
ATOM   556  C  CD2  . TYR   A 1 34  ? 47.25004 4.23483   -12.71650 1.000 31.42348  ? 34  TYR   A CD2  1 
ATOM   557  C  CE1  . TYR   A 1 34  ? 46.78956 3.82819   -15.40890 1.000 29.63269  ? 34  TYR   A CE1  1 
ATOM   558  C  CE2  . TYR   A 1 34  ? 46.49099 5.14544   -13.41320 1.000 24.45513  ? 34  TYR   A CE2  1 
ATOM   559  C  CZ   . TYR   A 1 34  ? 46.25925 4.93585   -14.78080 1.000 29.08001  ? 34  TYR   A CZ   1 
ATOM   560  O  OH   . TYR   A 1 34  ? 45.50640 5.82480   -15.49879 1.000 34.76241  ? 34  TYR   A OH   1 
ATOM   561  H  H    . TYR   A 1 34  ? 50.31230 0.46370   -11.96482 1.000 38.21817  ? 34  TYR   A H    1 
ATOM   562  H  HA   . TYR   A 1 34  ? 50.34565 2.52473   -13.55681 1.000 43.05884  ? 34  TYR   A HA   1 
ATOM   563  H  HB2  . TYR   A 1 34  ? 48.40791 1.23337   -12.89754 1.000 42.56461  ? 34  TYR   A HB2  1 
ATOM   564  H  HB3  . TYR   A 1 34  ? 48.34899 2.18173   -11.62375 1.000 42.56461  ? 34  TYR   A HB3  1 
ATOM   565  H  HD1  . TYR   A 1 34  ? 47.88995 2.17800   -15.11700 1.000 39.20007  ? 34  TYR   A HD1  1 
ATOM   566  H  HD2  . TYR   A 1 34  ? 47.39930 4.36889   -11.80840 1.000 37.72245  ? 34  TYR   A HD2  1 
ATOM   567  H  HE1  . TYR   A 1 34  ? 46.63794 3.68932   -16.31589 1.000 35.57349  ? 34  TYR   A HE1  1 
ATOM   568  H  HE2  . TYR   A 1 34  ? 46.13610 5.89005   -12.98365 1.000 29.36043  ? 34  TYR   A HE2  1 
ATOM   569  H  HH   . TYR   A 1 34  ? 45.13162 6.36876   -14.97990 1.000 41.72917  ? 34  TYR   A HH   1 
ATOM   570  N  N    . PRO   A 1 35  ? 50.85157 4.67465   -12.37569 1.000 28.88692  ? 35  PRO   A N    1 
ATOM   571  C  CA   . PRO   A 1 35  ? 51.48463 5.79163   -11.65845 1.000 30.88995  ? 35  PRO   A CA   1 
ATOM   572  C  C    . PRO   A 1 35  ? 50.52848 6.61226   -10.79240 1.000 31.67103  ? 35  PRO   A C    1 
ATOM   573  O  O    . PRO   A 1 35  ? 50.48714 7.83940   -10.87390 1.000 29.46630  ? 35  PRO   A O    1 
ATOM   574  C  CB   . PRO   A 1 35  ? 52.07521 6.63490   -12.79156 1.000 31.85423  ? 35  PRO   A CB   1 
ATOM   575  C  CG   . PRO   A 1 35  ? 51.14873 6.43353   -13.92770 1.000 28.10593  ? 35  PRO   A CG   1 
ATOM   576  C  CD   . PRO   A 1 35  ? 50.74629 4.94905   -13.82698 1.000 33.47223  ? 35  PRO   A CD   1 
ATOM   577  H  HA   . PRO   A 1 35  ? 52.19939 5.44766   -11.10014 1.000 37.08221  ? 35  PRO   A HA   1 
ATOM   578  H  HB2  . PRO   A 1 35  ? 52.10703 7.56810   -12.52881 1.000 38.23935  ? 35  PRO   A HB2  1 
ATOM   579  H  HB3  . PRO   A 1 35  ? 52.96685 6.32085   -13.00889 1.000 38.23935  ? 35  PRO   A HB3  1 
ATOM   580  H  HG2  . PRO   A 1 35  ? 50.37596 7.01248   -13.83528 1.000 33.74138  ? 35  PRO   A HG2  1 
ATOM   581  H  HG3  . PRO   A 1 35  ? 51.60238 6.61690   -14.76525 1.000 33.74138  ? 35  PRO   A HG3  1 
ATOM   582  H  HD2  . PRO   A 1 35  ? 49.83823 4.81412   -14.14023 1.000 40.18094  ? 35  PRO   A HD2  1 
ATOM   583  H  HD3  . PRO   A 1 35  ? 51.35764 4.38928   -14.33077 1.000 40.18094  ? 35  PRO   A HD3  1 
ATOM   584  N  N    . LEU   A 1 36  ? 49.76232 5.93208   -9.95184  1.000 30.51205  ? 36  LEU   A N    1 
ATOM   585  C  CA   . LEU   A 1 36  ? 48.88396 6.58295   -8.98144  1.000 30.98799  ? 36  LEU   A CA   1 
ATOM   586  C  C    . LEU   A 1 36  ? 49.31405 6.16134   -7.58375  1.000 38.05640  ? 36  LEU   A C    1 
ATOM   587  O  O    . LEU   A 1 36  ? 49.58910 4.97656   -7.34016  1.000 29.68935  ? 36  LEU   A O    1 
ATOM   588  C  CB   . LEU   A 1 36  ? 47.42772 6.21595   -9.20675  1.000 27.40895  ? 36  LEU   A CB   1 
ATOM   589  C  CG   . LEU   A 1 36  ? 46.36290 6.77951   -8.28284  1.000 27.89333  ? 36  LEU   A CG   1 
ATOM   590  C  CD1  . LEU   A 1 36  ? 46.26986 8.29687   -8.38039  1.000 32.90880  ? 36  LEU   A CD1  1 
ATOM   591  C  CD2  . LEU   A 1 36  ? 45.01184 6.15740   -8.57190  1.000 29.26082  ? 36  LEU   A CD2  1 
ATOM   592  H  H    . LEU   A 1 36  ? 49.73105 5.07318   -9.92145  1.000 36.62873  ? 36  LEU   A H    1 
ATOM   593  H  HA   . LEU   A 1 36  ? 48.95716 7.54673   -9.06316  1.000 37.19986  ? 36  LEU   A HA   1 
ATOM   594  H  HB2  . LEU   A 1 36  ? 47.19226 6.50605   -10.10190 1.000 32.90501  ? 36  LEU   A HB2  1 
ATOM   595  H  HB3  . LEU   A 1 36  ? 47.36024 5.25044   -9.14241  1.000 32.90501  ? 36  LEU   A HB3  1 
ATOM   596  H  HG   . LEU   A 1 36  ? 46.61835 6.55931   -7.37336  1.000 33.48626  ? 36  LEU   A HG   1 
ATOM   597  H  HD11 . LEU   A 1 36  ? 45.58804 8.61158   -7.76640  1.000 39.50483  ? 36  LEU   A HD11 1 
ATOM   598  H  HD12 . LEU   A 1 36  ? 47.12893 8.68164   -8.14620  1.000 39.50483  ? 36  LEU   A HD12 1 
ATOM   599  H  HD13 . LEU   A 1 36  ? 46.03474 8.54107   -9.28922  1.000 39.50483  ? 36  LEU   A HD13 1 
ATOM   600  H  HD21 . LEU   A 1 36  ? 44.35456 6.53422   -7.96619  1.000 35.12726  ? 36  LEU   A HD21 1 
ATOM   601  H  HD22 . LEU   A 1 36  ? 44.76499 6.35080   -9.48981  1.000 35.12726  ? 36  LEU   A HD22 1 
ATOM   602  H  HD23 . LEU   A 1 36  ? 45.07122 5.19818   -8.44043  1.000 35.12726  ? 36  LEU   A HD23 1 
ATOM   603  N  N    . ASN   A 1 37  ? 49.38044 7.12690   -6.67164  1.000 31.00582  ? 37  ASN   A N    1 
ATOM   604  C  CA   . ASN   A 1 37  ? 49.74511 6.83049   -5.28766  1.000 28.67859  ? 37  ASN   A CA   1 
ATOM   605  C  C    . ASN   A 1 37  ? 48.66825 5.94507   -4.67093  1.000 27.02082  ? 37  ASN   A C    1 
ATOM   606  O  O    . ASN   A 1 37  ? 47.49534 6.35888   -4.61207  1.000 28.49189  ? 37  ASN   A O    1 
ATOM   607  C  CB   . ASN   A 1 37  ? 49.90997 8.11971   -4.49375  1.000 34.00644  ? 37  ASN   A CB   1 
ATOM   608  C  CG   . ASN   A 1 37  ? 50.32441 7.86976   -3.05316  1.000 38.40095  ? 37  ASN   A CG   1 
ATOM   609  O  OD1  . ASN   A 1 37  ? 50.47147 6.72623   -2.61695  1.000 41.65901  ? 37  ASN   A OD1  1 
ATOM   610  N  ND2  . ASN   A 1 37  ? 50.54003 8.94247   -2.31491  1.000 43.91719  ? 37  ASN   A ND2  1 
ATOM   611  H  H    . ASN   A 1 37  ? 49.22011 7.95747   -6.82674  1.000 37.22125  ? 37  ASN   A H    1 
ATOM   612  H  HA   . ASN   A 1 37  ? 50.59401 6.36217   -5.25694  1.000 34.42859  ? 37  ASN   A HA   1 
ATOM   613  H  HB2  . ASN   A 1 37  ? 50.59419 8.66457   -4.91313  1.000 40.82200  ? 37  ASN   A HB2  1 
ATOM   614  H  HB3  . ASN   A 1 37  ? 49.06528 8.59649   -4.48510  1.000 40.82200  ? 37  ASN   A HB3  1 
ATOM   615  H  HD21 . ASN   A 1 37  ? 50.77679 8.85797   -1.49247  1.000 52.71490  ? 37  ASN   A HD21 1 
ATOM   616  H  HD22 . ASN   A 1 37  ? 50.44376 9.72590   -2.65635  1.000 52.71490  ? 37  ASN   A HD22 1 
ATOM   617  N  N    . PRO   A 1 38  ? 49.00403 4.74275   -4.20244  1.000 31.34249  ? 38  PRO   A N    1 
ATOM   618  C  CA   . PRO   A 1 38  ? 47.96235 3.87130   -3.62142  1.000 32.75196  ? 38  PRO   A CA   1 
ATOM   619  C  C    . PRO   A 1 38  ? 47.24584 4.47761   -2.42727  1.000 32.93560  ? 38  PRO   A C    1 
ATOM   620  O  O    . PRO   A 1 38  ? 46.06321 4.18863   -2.21370  1.000 30.50983  ? 38  PRO   A O    1 
ATOM   621  C  CB   . PRO   A 1 38  ? 48.74557 2.60945   -3.22188  1.000 35.81952  ? 38  PRO   A CB   1 
ATOM   622  C  CG   . PRO   A 1 38  ? 50.02375 2.67200   -3.97343  1.000 44.56850  ? 38  PRO   A CG   1 
ATOM   623  C  CD   . PRO   A 1 38  ? 50.34143 4.12229   -4.14836  1.000 37.20964  ? 38  PRO   A CD   1 
ATOM   624  H  HA   . PRO   A 1 38  ? 47.30945 3.64966   -4.30370  1.000 39.31662  ? 38  PRO   A HA   1 
ATOM   625  H  HB2  . PRO   A 1 38  ? 48.90799 2.61471   -2.26559  1.000 42.99769  ? 38  PRO   A HB2  1 
ATOM   626  H  HB3  . PRO   A 1 38  ? 48.23983 1.81921   -3.46815  1.000 42.99769  ? 38  PRO   A HB3  1 
ATOM   627  H  HG2  . PRO   A 1 38  ? 50.72113 2.22865   -3.46549  1.000 53.49647  ? 38  PRO   A HG2  1 
ATOM   628  H  HG3  . PRO   A 1 38  ? 49.91525 2.23998   -4.83511  1.000 53.49647  ? 38  PRO   A HG3  1 
ATOM   629  H  HD2  . PRO   A 1 38  ? 50.85091 4.45978   -3.39507  1.000 44.66584  ? 38  PRO   A HD2  1 
ATOM   630  H  HD3  . PRO   A 1 38  ? 50.82868 4.27430   -4.97321  1.000 44.66584  ? 38  PRO   A HD3  1 
ATOM   631  N  N    . ALA   A 1 39  ? 47.92947 5.29734   -1.63400  1.000 32.93038  ? 39  ALA   A N    1 
ATOM   632  C  CA   . ALA   A 1 39  ? 47.28935 5.94830   -0.49608  1.000 37.78575  ? 39  ALA   A CA   1 
ATOM   633  C  C    . ALA   A 1 39  ? 46.21548 6.91888   -0.95984  1.000 34.47132  ? 39  ALA   A C    1 
ATOM   634  O  O    . ALA   A 1 39  ? 45.18467 7.07260   -0.29480  1.000 34.59461  ? 39  ALA   A O    1 
ATOM   635  C  CB   . ALA   A 1 39  ? 48.32706 6.68067   0.35610   1.000 34.27341  ? 39  ALA   A CB   1 
ATOM   636  H  H    . ALA   A 1 39  ? 48.76119 5.49309   -1.73162  1.000 39.53072  ? 39  ALA   A H    1 
ATOM   637  H  HA   . ALA   A 1 39  ? 46.87624 5.26667   0.05674   1.000 45.35717  ? 39  ALA   A HA   1 
ATOM   638  H  HB1  . ALA   A 1 39  ? 47.87794 7.10944   1.10131   1.000 41.14236  ? 39  ALA   A HB1  1 
ATOM   639  H  HB2  . ALA   A 1 39  ? 48.97515 6.03854   0.68558   1.000 41.14236  ? 39  ALA   A HB2  1 
ATOM   640  H  HB3  . ALA   A 1 39  ? 48.77087 7.34768   -0.19075  1.000 41.14236  ? 39  ALA   A HB3  1 
ATOM   641  N  N    . THR   A 1 40  ? 46.44039 7.58848   -2.09932  1.000 32.18358  ? 40  THR   A N    1 
ATOM   642  C  CA   . THR   A 1 40  ? 45.40851 8.46138   -2.64199  1.000 28.52220  ? 40  THR   A CA   1 
ATOM   643  C  C    . THR   A 1 40  ? 44.22019 7.66413   -3.15015  1.000 28.00018  ? 40  THR   A C    1 
ATOM   644  O  O    . THR   A 1 40  ? 43.06310 8.02775   -2.89254  1.000 32.68796  ? 40  THR   A O    1 
ATOM   645  C  CB   . THR   A 1 40  ? 45.99581 9.34457   -3.73797  1.000 30.00079  ? 40  THR   A CB   1 
ATOM   646  O  OG1  . THR   A 1 40  ? 47.05670 10.13261  -3.17634  1.000 33.10090  ? 40  THR   A OG1  1 
ATOM   647  C  CG2  . THR   A 1 40  ? 44.92561 10.25407  -4.33094  1.000 37.50653  ? 40  THR   A CG2  1 
ATOM   648  H  H    . THR   A 1 40  ? 47.16497 7.55172   -2.56108  1.000 38.63457  ? 40  THR   A H    1 
ATOM   649  H  HA   . THR   A 1 40  ? 45.08546 9.04523   -1.93796  1.000 34.24091  ? 40  THR   A HA   1 
ATOM   650  H  HB   . THR   A 1 40  ? 46.34338 8.79614   -4.45861  1.000 36.01522  ? 40  THR   A HB   1 
ATOM   651  H  HG1  . THR   A 1 40  ? 47.33075 10.69012  -3.74174  1.000 39.73535  ? 40  THR   A HG1  1 
ATOM   652  H  HG21 . THR   A 1 40  ? 45.34045 10.95387  -4.85924  1.000 45.02211  ? 40  THR   A HG21 1 
ATOM   653  H  HG22 . THR   A 1 40  ? 44.33162 9.74015   -4.90012  1.000 45.02211  ? 40  THR   A HG22 1 
ATOM   654  H  HG23 . THR   A 1 40  ? 44.40608 10.66197  -3.62058  1.000 45.02211  ? 40  THR   A HG23 1 
ATOM   655  N  N    . LEU   A 1 41  ? 44.47488 6.56628   -3.86665  1.000 29.11139  ? 41  LEU   A N    1 
ATOM   656  C  CA   . LEU   A 1 41  ? 43.38590 5.68104   -4.25882  1.000 27.35319  ? 41  LEU   A CA   1 
ATOM   657  C  C    . LEU   A 1 41  ? 42.59910 5.20361   -3.03955  1.000 26.87108  ? 41  LEU   A C    1 
ATOM   658  O  O    . LEU   A 1 41  ? 41.35587 5.18863   -3.05698  1.000 29.60233  ? 41  LEU   A O    1 
ATOM   659  C  CB   . LEU   A 1 41  ? 43.92607 4.49188   -5.04774  1.000 30.05373  ? 41  LEU   A CB   1 
ATOM   660  C  CG   . LEU   A 1 41  ? 42.86845 3.48898   -5.53667  1.000 31.51640  ? 41  LEU   A CG   1 
ATOM   661  C  CD1  . LEU   A 1 41  ? 41.83928 4.18495   -6.41637  1.000 37.33344  ? 41  LEU   A CD1  1 
ATOM   662  C  CD2  . LEU   A 1 41  ? 43.52810 2.32590   -6.28177  1.000 36.26754  ? 41  LEU   A CD2  1 
ATOM   663  H  H    . LEU   A 1 41  ? 45.25469 6.31883   -4.13172  1.000 34.94794  ? 41  LEU   A H    1 
ATOM   664  H  HA   . LEU   A 1 41  ? 42.78083 6.17044   -4.83786  1.000 32.83810  ? 41  LEU   A HA   1 
ATOM   665  H  HB2  . LEU   A 1 41  ? 44.38819 4.83023   -5.83059  1.000 36.07875  ? 41  LEU   A HB2  1 
ATOM   666  H  HB3  . LEU   A 1 41  ? 44.54554 4.00628   -4.48087  1.000 36.07875  ? 41  LEU   A HB3  1 
ATOM   667  H  HG   . LEU   A 1 41  ? 42.40382 3.12092   -4.76885  1.000 37.83396  ? 41  LEU   A HG   1 
ATOM   668  H  HD11 . LEU   A 1 41  ? 41.26698 3.51555   -6.82290  1.000 44.81440  ? 41  LEU   A HD11 1 
ATOM   669  H  HD12 . LEU   A 1 41  ? 41.30923 4.78462   -5.86834  1.000 44.81440  ? 41  LEU   A HD12 1 
ATOM   670  H  HD13 . LEU   A 1 41  ? 42.30115 4.68782   -7.10536  1.000 44.81440  ? 41  LEU   A HD13 1 
ATOM   671  H  HD21 . LEU   A 1 41  ? 42.84114 1.70307   -6.56649  1.000 43.53532  ? 41  LEU   A HD21 1 
ATOM   672  H  HD22 . LEU   A 1 41  ? 44.00051 2.67323   -7.05449  1.000 43.53532  ? 41  LEU   A HD22 1 
ATOM   673  H  HD23 . LEU   A 1 41  ? 44.15092 1.88154   -5.68551  1.000 43.53532  ? 41  LEU   A HD23 1 
ATOM   674  N  N    . LEU   A 1 42  ? 43.29876 4.80040   -1.98336  1.000 30.15738  ? 42  LEU   A N    1 
ATOM   675  C  CA   . LEU   A 1 42  ? 42.62196 4.30896   -0.77974  1.000 28.87661  ? 42  LEU   A CA   1 
ATOM   676  C  C    . LEU   A 1 42  ? 41.71452 5.38009   -0.19717  1.000 29.44360  ? 42  LEU   A C    1 
ATOM   677  O  O    . LEU   A 1 42  ? 40.54290 5.12101   0.10027   1.000 36.42742  ? 42  LEU   A O    1 
ATOM   678  C  CB   . LEU   A 1 42  ? 43.64485 3.84353   0.23419   1.000 28.72396  ? 42  LEU   A CB   1 
ATOM   679  C  CG   . LEU   A 1 42  ? 43.07811 3.38832   1.58910   1.000 35.84086  ? 42  LEU   A CG   1 
ATOM   680  C  CD1  . LEU   A 1 42  ? 41.96869 2.37670   1.37250   1.000 43.41637  ? 42  LEU   A CD1  1 
ATOM   681  C  CD2  . LEU   A 1 42  ? 44.19070 2.79865   2.42576   1.000 33.48100  ? 42  LEU   A CD2  1 
ATOM   682  H  H    . LEU   A 1 42  ? 44.15736 4.79960   -1.93438  1.000 36.20313  ? 42  LEU   A H    1 
ATOM   683  H  HA   . LEU   A 1 42  ? 42.07035 3.54534   -1.01103  1.000 34.66620  ? 42  LEU   A HA   1 
ATOM   684  H  HB2  . LEU   A 1 42  ? 44.12766 3.09209   -0.14414  1.000 34.48302  ? 42  LEU   A HB2  1 
ATOM   685  H  HB3  . LEU   A 1 42  ? 44.25569 4.57666   0.40819   1.000 34.48302  ? 42  LEU   A HB3  1 
ATOM   686  H  HG   . LEU   A 1 42  ? 42.70229 4.14398   2.06726   1.000 43.02330  ? 42  LEU   A HG   1 
ATOM   687  H  HD11 . LEU   A 1 42  ? 41.65931 2.05783   2.23476   1.000 52.11392  ? 42  LEU   A HD11 1 
ATOM   688  H  HD12 . LEU   A 1 42  ? 41.23952 2.80463   0.89701   1.000 52.11392  ? 42  LEU   A HD12 1 
ATOM   689  H  HD13 . LEU   A 1 42  ? 42.31436 1.63585   0.85044   1.000 52.11392  ? 42  LEU   A HD13 1 
ATOM   690  H  HD21 . LEU   A 1 42  ? 43.84359 2.58185   3.30519   1.000 40.19147  ? 42  LEU   A HD21 1 
ATOM   691  H  HD22 . LEU   A 1 42  ? 44.51972 1.99543   1.99276   1.000 40.19147  ? 42  LEU   A HD22 1 
ATOM   692  H  HD23 . LEU   A 1 42  ? 44.90603 3.44915   2.50362   1.000 40.19147  ? 42  LEU   A HD23 1 
ATOM   693  N  N    . ASP   A 1 43  ? 42.22749 6.61354   -0.07449  1.000 32.34465  ? 43  ASP   A N    1 
ATOM   694  C  CA   A ASP   A 1 43  ? 41.42345 7.70157   0.47124   0.550 32.99121  ? 43  ASP   A CA   1 
ATOM   695  C  CA   B ASP   A 1 43  ? 41.42207 7.70014   0.47014   0.450 33.00412  ? 43  ASP   A CA   1 
ATOM   696  C  C    . ASP   A 1 43  ? 40.15819 7.91043   -0.35087  1.000 33.61623  ? 43  ASP   A C    1 
ATOM   697  O  O    . ASP   A 1 43  ? 39.06532 8.05396   0.20422   1.000 32.60061  ? 43  ASP   A O    1 
ATOM   698  C  CB   A ASP   A 1 43  ? 42.25168 8.98661   0.52238   0.550 34.32661  ? 43  ASP   A CB   1 
ATOM   699  C  CB   B ASP   A 1 43  ? 42.25331 8.98119   0.52407   0.450 34.32897  ? 43  ASP   A CB   1 
ATOM   700  C  CG   A ASP   A 1 43  ? 43.27699 8.98830   1.65142   0.550 36.72034  ? 43  ASP   A CG   1 
ATOM   701  C  CG   B ASP   A 1 43  ? 41.55765 10.09851  1.28610   0.450 30.79051  ? 43  ASP   A CG   1 
ATOM   702  O  OD1  A ASP   A 1 43  ? 43.11179 8.22519   2.62693   0.550 47.47077  ? 43  ASP   A OD1  1 
ATOM   703  O  OD1  B ASP   A 1 43  ? 41.31218 9.92855   2.49410   0.450 37.61216  ? 43  ASP   A OD1  1 
ATOM   704  O  OD2  A ASP   A 1 43  ? 44.25172 9.76935   1.56238   0.550 44.60321  ? 43  ASP   A OD2  1 
ATOM   705  O  OD2  B ASP   A 1 43  ? 41.26579 11.14341  0.67155   0.450 58.39006  ? 43  ASP   A OD2  1 
ATOM   706  H  H    A ASP   A 1 43  ? 43.02704 6.83789   -0.29808  0.550 38.82785  ? 43  ASP   A H    1 
ATOM   707  H  H    B ASP   A 1 43  ? 43.02712 6.83839   -0.29729  0.450 38.82785  ? 43  ASP   A H    1 
ATOM   708  H  HA   A ASP   A 1 43  ? 41.16094 7.47500   1.37713   0.550 39.60373  ? 43  ASP   A HA   1 
ATOM   709  H  HA   B ASP   A 1 43  ? 41.15475 7.47616   1.37528   0.450 39.61922  ? 43  ASP   A HA   1 
ATOM   710  H  HB2  A ASP   A 1 43  ? 42.72942 9.08752   -0.31576  0.550 41.20620  ? 43  ASP   A HB2  1 
ATOM   711  H  HB2  B ASP   A 1 43  ? 43.09529 8.79381   0.96775   0.450 41.20903  ? 43  ASP   A HB2  1 
ATOM   712  H  HB3  A ASP   A 1 43  ? 41.65635 9.74038   0.65775   0.550 41.20620  ? 43  ASP   A HB3  1 
ATOM   713  H  HB3  B ASP   A 1 43  ? 42.41671 9.29088   -0.38053  0.450 41.20903  ? 43  ASP   A HB3  1 
ATOM   714  N  N    A GLU   A 1 44  ? 40.29543 7.93616   -1.68158  0.500 30.04627  ? 44  GLU   A N    1 
ATOM   715  N  N    B GLU   A 1 44  ? 40.27343 7.90848   -1.67933  0.500 29.82296  ? 44  GLU   A N    1 
ATOM   716  C  CA   A GLU   A 1 44  ? 39.13771 8.12037   -2.54774  0.500 28.43193  ? 44  GLU   A CA   1 
ATOM   717  C  CA   B GLU   A 1 44  ? 39.08953 8.13891   -2.49806  0.500 28.54731  ? 44  GLU   A CA   1 
ATOM   718  C  C    A GLU   A 1 44  ? 38.18460 6.93922   -2.42767  0.500 35.06019  ? 44  GLU   A C    1 
ATOM   719  C  C    B GLU   A 1 44  ? 38.17080 6.92581   -2.49642  0.500 35.20856  ? 44  GLU   A C    1 
ATOM   720  O  O    A GLU   A 1 44  ? 36.95911 7.11005   -2.41733  0.500 28.95348  ? 44  GLU   A O    1 
ATOM   721  O  O    B GLU   A 1 44  ? 36.94997 7.06968   -2.63991  0.500 29.75985  ? 44  GLU   A O    1 
ATOM   722  C  CB   A GLU   A 1 44  ? 39.60333 8.30172   -3.99518  0.500 33.30982  ? 44  GLU   A CB   1 
ATOM   723  C  CB   B GLU   A 1 44  ? 39.50755 8.51228   -3.91659  0.500 34.33603  ? 44  GLU   A CB   1 
ATOM   724  C  CG   A GLU   A 1 44  ? 38.53137 8.80107   -4.95462  0.500 28.58448  ? 44  GLU   A CG   1 
ATOM   725  C  CG   B GLU   A 1 44  ? 40.28351 9.81210   -3.97867  0.500 28.71493  ? 44  GLU   A CG   1 
ATOM   726  C  CD   A GLU   A 1 44  ? 38.28039 10.29303  -4.83309  0.500 28.99733  ? 44  GLU   A CD   1 
ATOM   727  C  CD   B GLU   A 1 44  ? 39.48269 10.98989  -3.44706  0.500 37.09293  ? 44  GLU   A CD   1 
ATOM   728  O  OE1  A GLU   A 1 44  ? 39.06315 10.97600  -4.14718  0.500 34.47307  ? 44  GLU   A OE1  1 
ATOM   729  O  OE1  B GLU   A 1 44  ? 38.30363 11.12856  -3.84196  0.500 38.03940  ? 44  GLU   A OE1  1 
ATOM   730  O  OE2  A GLU   A 1 44  ? 37.29858 10.78143  -5.43407  0.500 43.07312  ? 44  GLU   A OE2  1 
ATOM   731  O  OE2  B GLU   A 1 44  ? 40.03354 11.76231  -2.63501  0.500 35.02087  ? 44  GLU   A OE2  1 
ATOM   732  H  H    A GLU   A 1 44  ? 41.04188 7.84981   -2.09985  0.500 36.06980  ? 44  GLU   A H    1 
ATOM   733  H  H    B GLU   A 1 44  ? 41.00315 7.78015   -2.11594  0.500 35.80183  ? 44  GLU   A H    1 
ATOM   734  H  HA   A GLU   A 1 44  ? 38.65819 8.92169   -2.28535  0.500 34.13259  ? 44  GLU   A HA   1 
ATOM   735  H  HA   B GLU   A 1 44  ? 38.58684 8.88553   -2.13645  0.500 34.27105  ? 44  GLU   A HA   1 
ATOM   736  H  HB2  A GLU   A 1 44  ? 40.32795 8.94647   -4.00663  0.500 39.98605  ? 44  GLU   A HB2  1 
ATOM   737  H  HB2  B GLU   A 1 44  ? 40.07149 7.80890   -4.27452  0.500 41.21750  ? 44  GLU   A HB2  1 
ATOM   738  H  HB3  A GLU   A 1 44  ? 39.91577 7.44557   -4.32727  0.500 39.98605  ? 44  GLU   A HB3  1 
ATOM   739  H  HB3  B GLU   A 1 44  ? 38.71274 8.61100   -4.46380  0.500 41.21750  ? 44  GLU   A HB3  1 
ATOM   740  H  HG2  A GLU   A 1 44  ? 38.81207 8.61769   -5.86483  0.500 34.31565  ? 44  GLU   A HG2  1 
ATOM   741  H  HG2  B GLU   A 1 44  ? 41.08771 9.72780   -3.44289  0.500 34.47219  ? 44  GLU   A HG2  1 
ATOM   742  H  HG3  A GLU   A 1 44  ? 37.69881 8.34083   -4.76509  0.500 34.31565  ? 44  GLU   A HG3  1 
ATOM   743  H  HG3  B GLU   A 1 44  ? 40.51762 9.99848   -4.90136  0.500 34.47219  ? 44  GLU   A HG3  1 
ATOM   744  N  N    . TYR   A 1 45  ? 38.73319 5.72891   -2.34198  1.000 29.14798  ? 45  TYR   A N    1 
ATOM   745  C  CA   . TYR   A 1 45  ? 37.90502 4.53371   -2.18570  1.000 31.11632  ? 45  TYR   A CA   1 
ATOM   746  C  C    . TYR   A 1 45  ? 37.06934 4.60890   -0.90676  1.000 25.06299  ? 45  TYR   A C    1 
ATOM   747  O  O    . TYR   A 1 45  ? 35.86401 4.32069   -0.91531  1.000 30.38502  ? 45  TYR   A O    1 
ATOM   748  C  CB   . TYR   A 1 45  ? 38.80931 3.29826   -2.15050  1.000 33.73550  ? 45  TYR   A CB   1 
ATOM   749  C  CG   . TYR   A 1 45  ? 38.14134 2.05654   -1.59856  1.000 40.63420  ? 45  TYR   A CG   1 
ATOM   750  C  CD1  . TYR   A 1 45  ? 37.44250 1.18894   -2.43045  1.000 46.07459  ? 45  TYR   A CD1  1 
ATOM   751  C  CD2  . TYR   A 1 45  ? 38.22021 1.75598   -0.24257  1.000 55.15499  ? 45  TYR   A CD2  1 
ATOM   752  C  CE1  . TYR   A 1 45  ? 36.82762 0.05621   -1.92103  1.000 54.95752  ? 45  TYR   A CE1  1 
ATOM   753  C  CE2  . TYR   A 1 45  ? 37.60773 0.62820   0.28360   1.000 52.31103  ? 45  TYR   A CE2  1 
ATOM   754  C  CZ   . TYR   A 1 45  ? 36.91807 -0.21784  -0.56272  1.000 60.04680  ? 45  TYR   A CZ   1 
ATOM   755  O  OH   . TYR   A 1 45  ? 36.31500 -1.33409  -0.04490  1.000 62.47750  ? 45  TYR   A OH   1 
ATOM   756  H  H    A TYR   A 1 45  ? 39.57817 5.57156   -2.37130  0.500 34.99184  ? 45  TYR   A H    1 
ATOM   757  H  H    B TYR   A 1 45  ? 39.58036 5.58195   -2.32416  0.500 34.99184  ? 45  TYR   A H    1 
ATOM   758  H  HA   . TYR   A 1 45  ? 37.29971 4.46314   -2.94036  1.000 37.35385  ? 45  TYR   A HA   1 
ATOM   759  H  HB2  . TYR   A 1 45  ? 39.09853 3.09961   -3.05482  1.000 40.49687  ? 45  TYR   A HB2  1 
ATOM   760  H  HB3  . TYR   A 1 45  ? 39.57791 3.49219   -1.59144  1.000 40.49687  ? 45  TYR   A HB3  1 
ATOM   761  H  HD1  . TYR   A 1 45  ? 37.38695 1.37113   -3.34074  1.000 55.30378  ? 45  TYR   A HD1  1 
ATOM   762  H  HD2  . TYR   A 1 45  ? 38.69336 2.32290   0.32279   1.000 66.20026  ? 45  TYR   A HD2  1 
ATOM   763  H  HE1  . TYR   A 1 45  ? 36.35818 -0.51579  -2.48436  1.000 65.96329  ? 45  TYR   A HE1  1 
ATOM   764  H  HE2  . TYR   A 1 45  ? 37.66071 0.44423   1.19368   1.000 62.78750  ? 45  TYR   A HE2  1 
ATOM   765  H  HH   . TYR   A 1 45  ? 36.45951 -1.38164  0.78121   1.000 74.98727  ? 45  TYR   A HH   1 
ATOM   766  N  N    . GLU   A 1 46  ? 37.68774 5.00364   0.19543   1.000 30.87463  ? 46  GLU   A N    1 
ATOM   767  C  CA   . GLU   A 1 46  ? 36.93566 5.07084   1.45651   1.000 37.84611  ? 46  GLU   A CA   1 
ATOM   768  C  C    . GLU   A 1 46  ? 35.82068 6.10425   1.36735   1.000 39.71525  ? 46  GLU   A C    1 
ATOM   769  O  O    . GLU   A 1 46  ? 34.68114 5.83398   1.75921   1.000 37.64853  ? 46  GLU   A O    1 
ATOM   770  C  CB   . GLU   A 1 46  ? 37.88982 5.35260   2.60909   1.000 39.02712  ? 46  GLU   A CB   1 
ATOM   771  C  CG   . GLU   A 1 46  ? 38.54107 4.07096   3.12155   1.000 43.88760  ? 46  GLU   A CG   1 
ATOM   772  C  CD   . GLU   A 1 46  ? 39.78773 4.30242   3.93952   1.000 46.14713  ? 46  GLU   A CD   1 
ATOM   773  O  OE1  . GLU   A 1 46  ? 40.27725 5.45414   3.99515   1.000 51.25917  ? 46  GLU   A OE1  1 
ATOM   774  O  OE2  . GLU   A 1 46  ? 40.28674 3.31783   4.52502   1.000 53.84874  ? 46  GLU   A OE2  1 
ATOM   775  H  H    . GLU   A 1 46  ? 38.51504 5.23259   0.24791   1.000 37.06383  ? 46  GLU   A H    1 
ATOM   776  H  HA   . GLU   A 1 46  ? 36.51695 4.21481   1.63757   1.000 45.42961  ? 46  GLU   A HA   1 
ATOM   777  H  HB2  . GLU   A 1 46  ? 38.59018 5.95155   2.30635   1.000 46.84682  ? 46  GLU   A HB2  1 
ATOM   778  H  HB3  . GLU   A 1 46  ? 37.39846 5.75926   3.33991   1.000 46.84682  ? 46  GLU   A HB3  1 
ATOM   779  H  HG2  . GLU   A 1 46  ? 37.90412 3.60020   3.68152   1.000 52.67939  ? 46  GLU   A HG2  1 
ATOM   780  H  HG3  . GLU   A 1 46  ? 38.78518 3.52006   2.36140   1.000 52.67939  ? 46  GLU   A HG3  1 
ATOM   781  N  N    . LYS   A 1 47  ? 36.10543 7.26819   0.78856   1.000 35.12362  ? 47  LYS   A N    1 
ATOM   782  C  CA   . LYS   A 1 47  ? 35.05039 8.25609   0.56329   1.000 37.85377  ? 47  LYS   A CA   1 
ATOM   783  C  C    . LYS   A 1 47  ? 33.86520 7.62889   -0.15923  1.000 39.60581  ? 47  LYS   A C    1 
ATOM   784  O  O    . LYS   A 1 47  ? 32.72974 7.66837   0.32689   1.000 39.76108  ? 47  LYS   A O    1 
ATOM   785  C  CB   . LYS   A 1 47  ? 35.59228 9.43982   -0.24155  1.000 45.32329  ? 47  LYS   A CB   1 
ATOM   786  C  CG   . LYS   A 1 47  ? 36.60113 10.30164  0.49566   1.000 49.67341  ? 47  LYS   A CG   1 
ATOM   787  C  CD   . LYS   A 1 47  ? 37.08594 11.44359  -0.40377  1.000 65.47988  ? 47  LYS   A CD   1 
ATOM   788  C  CE   . LYS   A 1 47  ? 38.28980 12.15913  0.20280   1.000 78.50435  ? 47  LYS   A CE   1 
ATOM   789  N  NZ   . LYS   A 1 47  ? 38.94221 13.08015  -0.77196  1.000 65.49304  ? 47  LYS   A NZ   1 
ATOM   790  H  H    . LYS   A 1 47  ? 36.88692 7.50773   0.52117   1.000 42.16261  ? 47  LYS   A H    1 
ATOM   791  H  HA   . LYS   A 1 47  ? 34.75221 8.58805   1.42457   1.000 45.43879  ? 47  LYS   A HA   1 
ATOM   792  H  HB2  . LYS   A 1 47  ? 36.02775 9.09718   -1.03771  1.000 54.40222  ? 47  LYS   A HB2  1 
ATOM   793  H  HB3  . LYS   A 1 47  ? 34.84777 10.00984  -0.48988  1.000 54.40222  ? 47  LYS   A HB3  1 
ATOM   794  H  HG2  . LYS   A 1 47  ? 36.18734 10.68391  1.28531   1.000 59.62237  ? 47  LYS   A HG2  1 
ATOM   795  H  HG3  . LYS   A 1 47  ? 37.36595 9.76202   0.75014   1.000 59.62237  ? 47  LYS   A HG3  1 
ATOM   796  H  HD2  . LYS   A 1 47  ? 37.34707 11.08478  -1.26631  1.000 78.59013  ? 47  LYS   A HD2  1 
ATOM   797  H  HD3  . LYS   A 1 47  ? 36.37148 12.09002  -0.51589  1.000 78.59013  ? 47  LYS   A HD3  1 
ATOM   798  H  HE2  . LYS   A 1 47  ? 37.99884 12.68248  0.96592   1.000 94.21949  ? 47  LYS   A HE2  1 
ATOM   799  H  HE3  . LYS   A 1 47  ? 38.94488 11.50066  0.48245   1.000 94.21949  ? 47  LYS   A HE3  1 
ATOM   800  H  HZ1  . LYS   A 1 47  ? 39.68262 13.42388  -0.41735  1.000 78.60592  ? 47  LYS   A HZ1  1 
ATOM   801  H  HZ2  . LYS   A 1 47  ? 39.15599 12.63682  -1.51349  1.000 78.60592  ? 47  LYS   A HZ2  1 
ATOM   802  H  HZ3  . LYS   A 1 47  ? 38.38753 13.74372  -0.98194  1.000 78.60592  ? 47  LYS   A HZ3  1 
ATOM   803  N  N    . LEU   A 1 48  ? 34.11736 7.03395   -1.33452  1.000 31.68904  ? 48  LEU   A N    1 
ATOM   804  C  CA   . LEU   A 1 48  ? 33.02964 6.49353   -2.13909  1.000 38.14084  ? 48  LEU   A CA   1 
ATOM   805  C  C    . LEU   A 1 48  ? 32.34218 5.32916   -1.43969  1.000 43.45175  ? 48  LEU   A C    1 
ATOM   806  O  O    . LEU   A 1 48  ? 31.12687 5.15259   -1.57937  1.000 39.60240  ? 48  LEU   A O    1 
ATOM   807  C  CB   . LEU   A 1 48  ? 33.55347 6.04847   -3.50624  1.000 32.53683  ? 48  LEU   A CB   1 
ATOM   808  C  CG   . LEU   A 1 48  ? 33.76516 7.14112   -4.54807  1.000 38.24745  ? 48  LEU   A CG   1 
ATOM   809  C  CD1  . LEU   A 1 48  ? 34.24494 6.54259   -5.88084  1.000 44.71190  ? 48  LEU   A CD1  1 
ATOM   810  C  CD2  . LEU   A 1 48  ? 32.49209 7.94556   -4.74606  1.000 51.86321  ? 48  LEU   A CD2  1 
ATOM   811  H  H    . LEU   A 1 48  ? 34.89946 6.93482   -1.67815  1.000 38.04112  ? 48  LEU   A H    1 
ATOM   812  H  HA   . LEU   A 1 48  ? 32.37324 7.19343   -2.28113  1.000 45.78328  ? 48  LEU   A HA   1 
ATOM   813  H  HB2  . LEU   A 1 48  ? 34.41037 5.61424   -3.37184  1.000 39.05847  ? 48  LEU   A HB2  1 
ATOM   814  H  HB3  . LEU   A 1 48  ? 32.91747 5.41875   -3.88021  1.000 39.05847  ? 48  LEU   A HB3  1 
ATOM   815  H  HG   . LEU   A 1 48  ? 34.45473 7.74501   -4.23072  1.000 45.91121  ? 48  LEU   A HG   1 
ATOM   816  H  HD11 . LEU   A 1 48  ? 34.39995 7.26217   -6.51257  1.000 53.66855  ? 48  LEU   A HD11 1 
ATOM   817  H  HD12 . LEU   A 1 48  ? 35.06828 6.05278   -5.72885  1.000 53.66855  ? 48  LEU   A HD12 1 
ATOM   818  H  HD13 . LEU   A 1 48  ? 33.56220 5.94407   -6.22221  1.000 53.66855  ? 48  LEU   A HD13 1 
ATOM   819  H  HD21 . LEU   A 1 48  ? 32.50392 8.34278   -5.63092  1.000 62.25013  ? 48  LEU   A HD21 1 
ATOM   820  H  HD22 . LEU   A 1 48  ? 31.72812 7.35421   -4.65912  1.000 62.25013  ? 48  LEU   A HD22 1 
ATOM   821  H  HD23 . LEU   A 1 48  ? 32.45015 8.64146   -4.07162  1.000 62.25013  ? 48  LEU   A HD23 1 
ATOM   822  N  N    . ALA   A 1 49  ? 33.09974 4.52674   -0.68733  1.000 47.15267  ? 49  ALA   A N    1 
ATOM   823  C  CA   . ALA   A 1 49  ? 32.51022 3.40862   0.04298   1.000 37.74937  ? 49  ALA   A CA   1 
ATOM   824  C  C    . ALA   A 1 49  ? 31.56086 3.90564   1.12720   1.000 48.21182  ? 49  ALA   A C    1 
ATOM   825  O  O    . ALA   A 1 49  ? 30.42917 3.42144   1.23924   1.000 48.39847  ? 49  ALA   A O    1 
ATOM   826  C  CB   . ALA   A 1 49  ? 33.61699 2.54094   0.65163   1.000 45.24052  ? 49  ALA   A CB   1 
ATOM   827  H  H    . ALA   A 1 49  ? 33.94967 4.60887   -0.58503  1.000 56.59747  ? 49  ALA   A H    1 
ATOM   828  H  HA   . ALA   A 1 49  ? 32.00262 2.86060   -0.57583  1.000 45.31351  ? 49  ALA   A HA   1 
ATOM   829  H  HB1  . ALA   A 1 49  ? 33.21086 1.80956   1.14260   1.000 54.30289  ? 49  ALA   A HB1  1 
ATOM   830  H  HB2  . ALA   A 1 49  ? 34.17300 2.19162   -0.06232  1.000 54.30289  ? 49  ALA   A HB2  1 
ATOM   831  H  HB3  . ALA   A 1 49  ? 34.15136 3.08519   1.25091   1.000 54.30289  ? 49  ALA   A HB3  1 
ATOM   832  N  N    . ARG   A 1 50  ? 32.01132 4.86438   1.94100   1.000 43.54576  ? 50  ARG   A N    1 
ATOM   833  C  CA   . ARG   A 1 50  ? 31.14406 5.45737   2.95467   1.000 42.74315  ? 50  ARG   A CA   1 
ATOM   834  C  C    . ARG   A 1 50  ? 29.86002 5.98551   2.32797   1.000 40.63360  ? 50  ARG   A C    1 
ATOM   835  O  O    . ARG   A 1 50  ? 28.75619 5.73514   2.82385   1.000 46.74572  ? 50  ARG   A O    1 
ATOM   836  C  CB   . ARG   A 1 50  ? 31.88269 6.57881   3.68801   1.000 45.02329  ? 50  ARG   A CB   1 
ATOM   837  C  CG   . ARG   A 1 50  ? 33.04962 6.11257   4.54442   1.000 65.73570  ? 50  ARG   A CG   1 
ATOM   838  C  CD   . ARG   A 1 50  ? 33.61104 7.24827   5.40718   1.000 78.62343  ? 50  ARG   A CD   1 
ATOM   839  N  NE   . ARG   A 1 50  ? 34.92069 7.71196   4.95536   1.000 88.56679  ? 50  ARG   A NE   1 
ATOM   840  C  CZ   . ARG   A 1 50  ? 35.14221 8.85689   4.31542   1.000 103.98960 ? 50  ARG   A CZ   1 
ATOM   841  N  NH1  . ARG   A 1 50  ? 34.15825 9.70162   4.03641   1.000 79.71556  ? 50  ARG   A NH1  1 
ATOM   842  N  NH2  . ARG   A 1 50  ? 36.38405 9.16585   3.95025   1.000 62.12708  ? 50  ARG   A NH2  1 
ATOM   843  H  H    . ARG   A 1 50  ? 32.80903 5.18534   1.92534   1.000 52.26918  ? 50  ARG   A H    1 
ATOM   844  H  HA   . ARG   A 1 50  ? 30.91066 4.77670   3.60514   1.000 51.30606  ? 50  ARG   A HA   1 
ATOM   845  H  HB2  . ARG   A 1 50  ? 32.23228 7.19994   3.03007   1.000 54.04222  ? 50  ARG   A HB2  1 
ATOM   846  H  HB3  . ARG   A 1 50  ? 31.25431 7.03234   4.27140   1.000 54.04222  ? 50  ARG   A HB3  1 
ATOM   847  H  HG2  . ARG   A 1 50  ? 32.75069 5.40262   5.13392   1.000 78.89711  ? 50  ARG   A HG2  1 
ATOM   848  H  HG3  . ARG   A 1 50  ? 33.76005 5.78875   3.96880   1.000 78.89711  ? 50  ARG   A HG3  1 
ATOM   849  H  HD2  . ARG   A 1 50  ? 32.99989 8.00084   5.37501   1.000 94.36238  ? 50  ARG   A HD2  1 
ATOM   850  H  HD3  . ARG   A 1 50  ? 33.70350 6.93479   6.32046   1.000 94.36238  ? 50  ARG   A HD3  1 
ATOM   851  H  HE   . ARG   A 1 50  ? 35.59858 7.20737   5.11493   1.000 106.29442 ? 50  ARG   A HE   1 
ATOM   852  H  HH11 . ARG   A 1 50  ? 33.35200 9.51499   4.27036   1.000 95.67294  ? 50  ARG   A HH11 1 
ATOM   853  H  HH12 . ARG   A 1 50  ? 34.32657 10.43591  3.62158   1.000 95.67294  ? 50  ARG   A HH12 1 
ATOM   854  H  HH21 . ARG   A 1 50  ? 37.03106 8.62808   4.12852   1.000 74.56676  ? 50  ARG   A HH21 1 
ATOM   855  H  HH22 . ARG   A 1 50  ? 36.53956 9.90328   3.53598   1.000 74.56676  ? 50  ARG   A HH22 1 
ATOM   856  N  N    . GLU   A 1 51  ? 29.98675 6.72229   1.23028   1.000 44.43654  ? 51  GLU   A N    1 
ATOM   857  C  CA   . GLU   A 1 51  ? 28.81268 7.22487   0.52881   1.000 44.55245  ? 51  GLU   A CA   1 
ATOM   858  C  C    . GLU   A 1 51  ? 27.89462 6.08091   0.12147   1.000 58.75771  ? 51  GLU   A C    1 
ATOM   859  O  O    . GLU   A 1 51  ? 26.67947 6.13428   0.34551   1.000 51.03066  ? 51  GLU   A O    1 
ATOM   860  C  CB   . GLU   A 1 51  ? 29.26331 8.04597   -0.68588  1.000 46.52778  ? 51  GLU   A CB   1 
ATOM   861  C  CG   . GLU   A 1 51  ? 28.21861 8.26035   -1.77692  1.000 86.47225  ? 51  GLU   A CG   1 
ATOM   862  C  CD   . GLU   A 1 51  ? 28.84505 8.28679   -3.17193  1.000 104.92478 ? 51  GLU   A CD   1 
ATOM   863  O  OE1  . GLU   A 1 51  ? 29.07760 7.19842   -3.74338  1.000 89.40294  ? 51  GLU   A OE1  1 
ATOM   864  O  OE2  . GLU   A 1 51  ? 29.12319 9.39113   -3.68627  1.000 97.72683  ? 51  GLU   A OE2  1 
ATOM   865  H  H    . GLU   A 1 51  ? 30.73654 6.94452   0.87249   1.000 53.33812  ? 51  GLU   A H    1 
ATOM   866  H  HA   . GLU   A 1 51  ? 28.30521 7.80956   1.11320   1.000 53.47721  ? 51  GLU   A HA   1 
ATOM   867  H  HB2  . GLU   A 1 51  ? 29.53526 8.92328   -0.37401  1.000 55.84761  ? 51  GLU   A HB2  1 
ATOM   868  H  HB3  . GLU   A 1 51  ? 30.01588 7.59161   -1.09587  1.000 55.84761  ? 51  GLU   A HB3  1 
ATOM   869  H  HG2  . GLU   A 1 51  ? 27.57364 7.53642   -1.74781  1.000 103.78097 ? 51  GLU   A HG2  1 
ATOM   870  H  HG3  . GLU   A 1 51  ? 27.77209 9.10864   -1.62890  1.000 103.78097 ? 51  GLU   A HG3  1 
ATOM   871  N  N    . ALA   A 1 52  ? 28.45625 5.03792   -0.48932  1.000 51.55062  ? 52  ALA   A N    1 
ATOM   872  C  CA   . ALA   A 1 52  ? 27.62613 3.95461   -1.01198  1.000 50.68919  ? 52  ALA   A CA   1 
ATOM   873  C  C    . ALA   A 1 52  ? 26.89084 3.22638   0.10560   1.000 47.03814  ? 52  ALA   A C    1 
ATOM   874  O  O    . ALA   A 1 52  ? 25.70611 2.90140   -0.03377  1.000 50.63615  ? 52  ALA   A O    1 
ATOM   875  C  CB   . ALA   A 1 52  ? 28.48326 2.97341   -1.80626  1.000 56.97814  ? 52  ALA   A CB   1 
ATOM   876  H  H    . ALA   A 1 52  ? 29.30111 4.93453   -0.61226  1.000 61.87502  ? 52  ALA   A H    1 
ATOM   877  H  HA   . ALA   A 1 52  ? 26.96438 4.33565   -1.61014  1.000 60.84129  ? 52  ALA   A HA   1 
ATOM   878  H  HB1  . ALA   A 1 52  ? 27.91872 2.25790   -2.13825  1.000 68.38804  ? 52  ALA   A HB1  1 
ATOM   879  H  HB2  . ALA   A 1 52  ? 28.89396 3.44257   -2.54931  1.000 68.38804  ? 52  ALA   A HB2  1 
ATOM   880  H  HB3  . ALA   A 1 52  ? 29.16930 2.61056   -1.22437  1.000 68.38804  ? 52  ALA   A HB3  1 
ATOM   881  N  N    . PHE   A 1 53  ? 27.57245 2.96303   1.22225   1.000 42.92644  ? 53  PHE   A N    1 
ATOM   882  C  CA   . PHE   A 1 53  ? 26.92909 2.26946   2.33058   1.000 50.65673  ? 53  PHE   A CA   1 
ATOM   883  C  C    . PHE   A 1 53  ? 25.83719 3.12669   2.95968   1.000 60.42407  ? 53  PHE   A C    1 
ATOM   884  O  O    . PHE   A 1 53  ? 24.77348 2.61314   3.33169   1.000 60.32379  ? 53  PHE   A O    1 
ATOM   885  C  CB   . PHE   A 1 53  ? 27.96193 1.86976   3.38453   1.000 57.92708  ? 53  PHE   A CB   1 
ATOM   886  C  CG   . PHE   A 1 53  ? 28.97186 0.86082   2.89639   1.000 53.03681  ? 53  PHE   A CG   1 
ATOM   887  C  CD1  . PHE   A 1 53  ? 28.66059 -0.00841  1.86831   1.000 47.87511  ? 53  PHE   A CD1  1 
ATOM   888  C  CD2  . PHE   A 1 53  ? 30.22963 0.78820   3.47755   1.000 84.99798  ? 53  PHE   A CD2  1 
ATOM   889  C  CE1  . PHE   A 1 53  ? 29.59055 -0.93094  1.41304   1.000 62.43270  ? 53  PHE   A CE1  1 
ATOM   890  C  CE2  . PHE   A 1 53  ? 31.16265 -0.13237  3.03517   1.000 67.42858  ? 53  PHE   A CE2  1 
ATOM   891  C  CZ   . PHE   A 1 53  ? 30.84102 -0.99157  1.99939   1.000 67.16750  ? 53  PHE   A CZ   1 
ATOM   892  H  H    . PHE   A 1 53  ? 28.39518 3.17287   1.35893   1.000 51.52600  ? 53  PHE   A H    1 
ATOM   893  H  HA   . PHE   A 1 53  ? 26.52238 1.45805   1.98837   1.000 60.80235  ? 53  PHE   A HA   1 
ATOM   894  H  HB2  . PHE   A 1 53  ? 28.44661 2.66275   3.66230   1.000 69.52677  ? 53  PHE   A HB2  1 
ATOM   895  H  HB3  . PHE   A 1 53  ? 27.49874 1.48132   4.14313   1.000 69.52677  ? 53  PHE   A HB3  1 
ATOM   896  H  HD1  . PHE   A 1 53  ? 27.81756 0.02564   1.47711   1.000 57.46441  ? 53  PHE   A HD1  1 
ATOM   897  H  HD2  . PHE   A 1 53  ? 30.44817 1.36556   4.17311   1.000 102.01185 ? 53  PHE   A HD2  1 
ATOM   898  H  HE1  . PHE   A 1 53  ? 29.37374 -1.50681  0.71571   1.000 74.93351  ? 53  PHE   A HE1  1 
ATOM   899  H  HE2  . PHE   A 1 53  ? 32.00259 -0.17359  3.43230   1.000 80.92857  ? 53  PHE   A HE2  1 
ATOM   900  H  HZ   . PHE   A 1 53  ? 31.46639 -1.61018  1.69749   1.000 80.61528  ? 53  PHE   A HZ   1 
ATOM   901  N  N    . SER   A 1 54  ? 26.08361 4.43302   3.10319   1.000 71.98608  ? 54  SER   A N    1 
ATOM   902  C  CA   A SER   A 1 54  ? 25.05726 5.31791   3.64425   0.350 54.85526  ? 54  SER   A CA   1 
ATOM   903  C  CA   B SER   A 1 54  ? 25.05648 5.31454   3.64795   0.650 54.84220  ? 54  SER   A CA   1 
ATOM   904  C  C    . SER   A 1 54  ? 23.77715 5.24687   2.82267   1.000 49.16848  ? 54  SER   A C    1 
ATOM   905  O  O    . SER   A 1 54  ? 22.67693 5.36060   3.37458   1.000 54.18812  ? 54  SER   A O    1 
ATOM   906  C  CB   A SER   A 1 54  ? 25.57736 6.75500   3.69713   0.350 58.83730  ? 54  SER   A CB   1 
ATOM   907  C  CB   B SER   A 1 54  ? 25.56973 6.75451   3.71093   0.650 58.91600  ? 54  SER   A CB   1 
ATOM   908  O  OG   A SER   A 1 54  ? 24.58805 7.63771   4.19384   0.350 44.48757  ? 54  SER   A OG   1 
ATOM   909  O  OG   B SER   A 1 54  ? 25.63734 7.33035   2.41488   0.650 67.85485  ? 54  SER   A OG   1 
ATOM   910  H  H    A SER   A 1 54  ? 26.82290 4.82162   2.89816   0.350 86.39757  ? 54  SER   A H    1 
ATOM   911  H  H    B SER   A 1 54  ? 26.82188 4.82267   2.89649   0.650 86.39757  ? 54  SER   A H    1 
ATOM   912  H  HA   A SER   A 1 54  ? 24.85015 5.04300   4.55112   0.350 65.84058  ? 54  SER   A HA   1 
ATOM   913  H  HA   B SER   A 1 54  ? 24.85213 5.03334   4.55353   0.650 65.82491  ? 54  SER   A HA   1 
ATOM   914  H  HB2  A SER   A 1 54  ? 26.35084 6.78837   4.28152   0.350 70.61903  ? 54  SER   A HB2  1 
ATOM   915  H  HB2  B SER   A 1 54  ? 24.96536 7.28039   4.25781   0.650 70.71347  ? 54  SER   A HB2  1 
ATOM   916  H  HB3  A SER   A 1 54  ? 25.82591 7.03281   2.80162   0.350 70.61903  ? 54  SER   A HB3  1 
ATOM   917  H  HB3  B SER   A 1 54  ? 26.45723 6.75543   4.10240   0.650 70.71347  ? 54  SER   A HB3  1 
ATOM   918  H  HG   A SER   A 1 54  ? 24.88840 8.42182   4.21753   0.350 53.39936  ? 54  SER   A HG   1 
ATOM   919  H  HG   B SER   A 1 54  ? 26.14671 6.87631   1.92499   0.650 81.44009  ? 54  SER   A HG   1 
ATOM   920  N  N    . ASN   A 1 55  ? 23.89727 5.05930   1.50767   1.000 44.16764  ? 55  ASN   A N    1 
ATOM   921  C  CA   . ASN   A 1 55  ? 22.71225 4.90871   0.67359   1.000 50.80719  ? 55  ASN   A CA   1 
ATOM   922  C  C    . ASN   A 1 55  ? 21.94218 3.63391   1.00135   1.000 65.44056  ? 55  ASN   A C    1 
ATOM   923  O  O    . ASN   A 1 55  ? 20.74021 3.55664   0.72025   1.000 57.20892  ? 55  ASN   A O    1 
ATOM   924  C  CB   . ASN   A 1 55  ? 23.09465 4.89780   -0.80816  1.000 61.77212  ? 55  ASN   A CB   1 
ATOM   925  C  CG   . ASN   A 1 55  ? 23.59223 6.25020   -1.29843  1.000 70.11722  ? 55  ASN   A CG   1 
ATOM   926  O  OD1  . ASN   A 1 55  ? 23.28824 7.28667   -0.71065  1.000 61.44479  ? 55  ASN   A OD1  1 
ATOM   927  N  ND2  . ASN   A 1 55  ? 24.35885 6.24097   -2.38491  1.000 62.30624  ? 55  ASN   A ND2  1 
ATOM   928  H  H    . ASN   A 1 55  ? 24.64365 5.01641   1.08260   1.000 53.01544  ? 55  ASN   A H    1 
ATOM   929  H  HA   . ASN   A 1 55  ? 22.13313 5.67145   0.82769   1.000 60.98290  ? 55  ASN   A HA   1 
ATOM   930  H  HB2  . ASN   A 1 55  ? 23.80268 4.24949   -0.94703  1.000 74.14082  ? 55  ASN   A HB2  1 
ATOM   931  H  HB3  . ASN   A 1 55  ? 22.31594 4.65632   -1.33371  1.000 74.14082  ? 55  ASN   A HB3  1 
ATOM   932  H  HD21 . ASN   A 1 55  ? 24.66505 6.97966   -2.70141  1.000 74.78176  ? 55  ASN   A HD21 1 
ATOM   933  H  HD22 . ASN   A 1 55  ? 24.54845 5.49630   -2.77108  1.000 74.78176  ? 55  ASN   A HD22 1 
ATOM   934  N  N    . TYR   A 1 56  ? 22.61037 2.63468   1.57847   1.000 49.90839  ? 56  TYR   A N    1 
ATOM   935  C  CA   . TYR   A 1 56  ? 22.00524 1.34114   1.86223   1.000 51.52127  ? 56  TYR   A CA   1 
ATOM   936  C  C    . TYR   A 1 56  ? 21.63088 1.14933   3.32930   1.000 49.44461  ? 56  TYR   A C    1 
ATOM   937  O  O    . TYR   A 1 56  ? 20.97327 0.15510   3.66355   1.000 41.30664  ? 56  TYR   A O    1 
ATOM   938  C  CB   . TYR   A 1 56  ? 22.95880 0.21115   1.43568   1.000 49.91695  ? 56  TYR   A CB   1 
ATOM   939  C  CG   . TYR   A 1 56  ? 23.00045 -0.01772  -0.05717  1.000 52.03337  ? 56  TYR   A CG   1 
ATOM   940  C  CD1  . TYR   A 1 56  ? 22.00617 -0.74509  -0.69376  1.000 47.22635  ? 56  TYR   A CD1  1 
ATOM   941  C  CD2  . TYR   A 1 56  ? 24.03547 0.49231   -0.83335  1.000 52.83957  ? 56  TYR   A CD2  1 
ATOM   942  C  CE1  . TYR   A 1 56  ? 22.03328 -0.95625  -2.05258  1.000 46.40086  ? 56  TYR   A CE1  1 
ATOM   943  C  CE2  . TYR   A 1 56  ? 24.07104 0.29102   -2.19227  1.000 41.96933  ? 56  TYR   A CE2  1 
ATOM   944  C  CZ   . TYR   A 1 56  ? 23.06830 -0.43982  -2.80253  1.000 43.40374  ? 56  TYR   A CZ   1 
ATOM   945  O  OH   . TYR   A 1 56  ? 23.08749 -0.65065  -4.15377  1.000 49.94372  ? 56  TYR   A OH   1 
ATOM   946  H  H    . TYR   A 1 56  ? 23.43437 2.68627   1.81924   1.000 59.90434  ? 56  TYR   A H    1 
ATOM   947  H  HA   . TYR   A 1 56  ? 21.18986 1.26570   1.34226   1.000 61.83979  ? 56  TYR   A HA   1 
ATOM   948  H  HB2  . TYR   A 1 56  ? 23.85689 0.43439   1.72635   1.000 59.91462  ? 56  TYR   A HB2  1 
ATOM   949  H  HB3  . TYR   A 1 56  ? 22.67042 -0.61507  1.85413   1.000 59.91462  ? 56  TYR   A HB3  1 
ATOM   950  H  HD1  . TYR   A 1 56  ? 21.30693 -1.09722  -0.19180  1.000 56.68589  ? 56  TYR   A HD1  1 
ATOM   951  H  HD2  . TYR   A 1 56  ? 24.71558 0.97818   -0.42559  1.000 63.42175  ? 56  TYR   A HD2  1 
ATOM   952  H  HE1  . TYR   A 1 56  ? 21.35690 -1.44485  -2.46329  1.000 55.69531  ? 56  TYR   A HE1  1 
ATOM   953  H  HE2  . TYR   A 1 56  ? 24.76611 0.64459   -2.69899  1.000 50.37747  ? 56  TYR   A HE2  1 
ATOM   954  H  HH   . TYR   A 1 56  ? 23.73894 -0.24747  -4.49823  1.000 59.94674  ? 56  TYR   A HH   1 
ATOM   955  N  N    . ALA   A 1 57  ? 22.02487 2.05869   4.20955   1.000 46.75600  ? 57  ALA   A N    1 
ATOM   956  C  CA   . ALA   A 1 57  ? 21.70053 1.91103   5.62254   1.000 58.98793  ? 57  ALA   A CA   1 
ATOM   957  C  C    . ALA   A 1 57  ? 20.20555 1.68357   5.78662   1.000 53.92435  ? 57  ALA   A C    1 
ATOM   958  O  O    . ALA   A 1 57  ? 19.38923 2.40046   5.19999   1.000 45.74655  ? 57  ALA   A O    1 
ATOM   959  C  CB   . ALA   A 1 57  ? 22.13916 3.15091   6.40144   1.000 54.28874  ? 57  ALA   A CB   1 
ATOM   960  H  H    . ALA   A 1 57  ? 22.47714 2.76451   4.01751   1.000 56.12148  ? 57  ALA   A H    1 
ATOM   961  H  HA   . ALA   A 1 57  ? 22.17781 1.15024   5.98901   1.000 70.79979  ? 57  ALA   A HA   1 
ATOM   962  H  HB1  . ALA   A 1 57  ? 21.90850 3.03448   7.33640   1.000 65.16076  ? 57  ALA   A HB1  1 
ATOM   963  H  HB2  . ALA   A 1 57  ? 23.09860 3.25922   6.30846   1.000 65.16076  ? 57  ALA   A HB2  1 
ATOM   964  H  HB3  . ALA   A 1 57  ? 21.68226 3.92752   6.04225   1.000 65.16076  ? 57  ALA   A HB3  1 
ATOM   965  N  N    . GLY   A 1 58  ? 19.85538 0.65514   6.55575   1.000 48.01738  ? 58  GLY   A N    1 
ATOM   966  C  CA   . GLY   A 1 58  ? 18.47637 0.32212   6.82615   1.000 41.96600  ? 58  GLY   A CA   1 
ATOM   967  C  C    . GLY   A 1 58  ? 17.74343 -0.38916  5.71516   1.000 49.66380  ? 58  GLY   A C    1 
ATOM   968  O  O    . GLY   A 1 58  ? 16.58206 -0.77812  5.91090   1.000 49.82647  ? 58  GLY   A O    1 
ATOM   969  H  H    . GLY   A 1 58  ? 20.41718 0.12776   6.93765   1.000 57.63512  ? 58  GLY   A H    1 
ATOM   970  H  HA2  . GLY   A 1 58  ? 18.44657 -0.25016  7.60878   1.000 50.37347  ? 58  GLY   A HA2  1 
ATOM   971  H  HA3  . GLY   A 1 58  ? 17.99411 1.14206   7.01594   1.000 50.37347  ? 58  GLY   A HA3  1 
ATOM   972  N  N    . LYS   A 1 59  ? 18.36516 -0.57804  4.56303   1.000 43.47590  ? 59  LYS   A N    1 
ATOM   973  C  CA   . LYS   A 1 59  ? 17.68274 -1.11466  3.40023   1.000 42.00132  ? 59  LYS   A CA   1 
ATOM   974  C  C    . LYS   A 1 59  ? 17.87420 -2.61664  3.31064   1.000 40.72086  ? 59  LYS   A C    1 
ATOM   975  O  O    . LYS   A 1 59  ? 18.71161 -3.19881  4.00948   1.000 39.73913  ? 59  LYS   A O    1 
ATOM   976  C  CB   . LYS   A 1 59  ? 18.20115 -0.43110  2.14022   1.000 48.15215  ? 59  LYS   A CB   1 
ATOM   977  C  CG   . LYS   A 1 59  ? 17.78631 1.03108   2.01821   1.000 65.75865  ? 59  LYS   A CG   1 
ATOM   978  C  CD   . LYS   A 1 59  ? 17.56279 1.41764   0.55351   1.000 104.00680 ? 59  LYS   A CD   1 
ATOM   979  C  CE   . LYS   A 1 59  ? 17.18320 2.88718   0.40700   1.000 71.08721  ? 59  LYS   A CE   1 
ATOM   980  N  NZ   . LYS   A 1 59  ? 16.42229 3.40266   1.58470   1.000 72.18517  ? 59  LYS   A NZ   1 
ATOM   981  H  H    . LYS   A 1 59  ? 19.19567 -0.39993  4.42839   1.000 52.18535  ? 59  LYS   A H    1 
ATOM   982  H  HA   . LYS   A 1 59  ? 16.73265 -0.93601  3.47970   1.000 50.41585  ? 59  LYS   A HA   1 
ATOM   983  H  HB2  . LYS   A 1 59  ? 19.17057 -0.46435  2.14407   1.000 57.79685  ? 59  LYS   A HB2  1 
ATOM   984  H  HB3  . LYS   A 1 59  ? 17.85610 -0.90223  1.36570   1.000 57.79685  ? 59  LYS   A HB3  1 
ATOM   985  H  HG2  . LYS   A 1 59  ? 16.95840 1.17371   2.50310   1.000 78.92465  ? 59  LYS   A HG2  1 
ATOM   986  H  HG3  . LYS   A 1 59  ? 18.48538 1.59680   2.38174   1.000 78.92465  ? 59  LYS   A HG3  1 
ATOM   987  H  HD2  . LYS   A 1 59  ? 18.37970 1.26385   0.05360   1.000 124.82243 ? 59  LYS   A HD2  1 
ATOM   988  H  HD3  . LYS   A 1 59  ? 16.84330 0.88027   0.18682   1.000 124.82243 ? 59  LYS   A HD3  1 
ATOM   989  H  HE2  . LYS   A 1 59  ? 17.99137 3.41592   0.31647   1.000 85.31892  ? 59  LYS   A HE2  1 
ATOM   990  H  HE3  . LYS   A 1 59  ? 16.62692 2.99400   -0.38043  1.000 85.31892  ? 59  LYS   A HE3  1 
ATOM   991  H  HZ1  . LYS   A 1 59  ? 16.14744 4.23472   1.42905   1.000 86.63647  ? 59  LYS   A HZ1  1 
ATOM   992  H  HZ2  . LYS   A 1 59  ? 15.71255 2.88787   1.73758   1.000 86.63647  ? 59  LYS   A HZ2  1 
ATOM   993  H  HZ3  . LYS   A 1 59  ? 16.94173 3.40048   2.30739   1.000 86.63647  ? 59  LYS   A HZ3  1 
ATOM   994  N  N    . PRO   A 1 60  ? 17.09038 -3.27913  2.45867   1.000 37.96926  ? 60  PRO   A N    1 
ATOM   995  C  CA   . PRO   A 1 60  ? 17.30938 -4.70721  2.21232   1.000 40.06891  ? 60  PRO   A CA   1 
ATOM   996  C  C    . PRO   A 1 60  ? 18.73713 -4.96726  1.77176   1.000 48.75319  ? 60  PRO   A C    1 
ATOM   997  O  O    . PRO   A 1 60  ? 19.37346 -4.13256  1.12266   1.000 41.65631  ? 60  PRO   A O    1 
ATOM   998  C  CB   . PRO   A 1 60  ? 16.30446 -5.03966  1.10111   1.000 44.40007  ? 60  PRO   A CB   1 
ATOM   999  C  CG   . PRO   A 1 60  ? 15.21789 -4.03623  1.28383   1.000 44.69381  ? 60  PRO   A CG   1 
ATOM   1000 C  CD   . PRO   A 1 60  ? 15.90609 -2.77061  1.73500   1.000 48.58770  ? 60  PRO   A CD   1 
ATOM   1001 H  HA   . PRO   A 1 60  ? 17.10460 -5.23469  3.00018   1.000 48.09696  ? 60  PRO   A HA   1 
ATOM   1002 H  HB2  . PRO   A 1 60  ? 16.72487 -4.94681  0.23190   1.000 53.29435  ? 60  PRO   A HB2  1 
ATOM   1003 H  HB3  . PRO   A 1 60  ? 15.96971 -5.94318  1.21292   1.000 53.29435  ? 60  PRO   A HB3  1 
ATOM   1004 H  HG2  . PRO   A 1 60  ? 14.75577 -3.89598  0.44259   1.000 53.64685  ? 60  PRO   A HG2  1 
ATOM   1005 H  HG3  . PRO   A 1 60  ? 14.59336 -4.34770  1.95751   1.000 53.64685  ? 60  PRO   A HG3  1 
ATOM   1006 H  HD2  . PRO   A 1 60  ? 16.17034 -2.22959  0.97449   1.000 58.31951  ? 60  PRO   A HD2  1 
ATOM   1007 H  HD3  . PRO   A 1 60  ? 15.33356 -2.25609  2.32524   1.000 58.31951  ? 60  PRO   A HD3  1 
ATOM   1008 N  N    . TYR   A 1 61  ? 19.22176 -6.15467  2.11491   1.000 38.95610  ? 61  TYR   A N    1 
ATOM   1009 C  CA   A TYR   A 1 61  ? 20.62267 -6.49965  1.91671   0.550 37.56427  ? 61  TYR   A CA   1 
ATOM   1010 C  CA   B TYR   A 1 61  ? 20.62402 -6.46948  1.91464   0.450 37.75513  ? 61  TYR   A CA   1 
ATOM   1011 C  C    . TYR   A 1 61  ? 20.94642 -6.67423  0.43972   1.000 35.33878  ? 61  TYR   A C    1 
ATOM   1012 O  O    . TYR   A 1 61  ? 20.13692 -7.16324  -0.34170  1.000 40.70351  ? 61  TYR   A O    1 
ATOM   1013 C  CB   A TYR   A 1 61  ? 20.95289 -7.78246  2.68385   0.550 31.78702  ? 61  TYR   A CB   1 
ATOM   1014 C  CB   B TYR   A 1 61  ? 21.01068 -7.71891  2.69572   0.450 31.90707  ? 61  TYR   A CB   1 
ATOM   1015 C  CG   A TYR   A 1 61  ? 22.22068 -8.48679  2.25823   0.550 33.88802  ? 61  TYR   A CG   1 
ATOM   1016 C  CG   B TYR   A 1 61  ? 22.49876 -7.86888  2.88003   0.450 35.18768  ? 61  TYR   A CG   1 
ATOM   1017 C  CD1  A TYR   A 1 61  ? 23.44812 -8.14411  2.81283   0.550 40.92137  ? 61  TYR   A CD1  1 
ATOM   1018 C  CD1  B TYR   A 1 61  ? 23.18969 -7.04226  3.75004   0.450 43.62046  ? 61  TYR   A CD1  1 
ATOM   1019 C  CD2  A TYR   A 1 61  ? 22.18821 -9.51237  1.32258   0.550 37.34307  ? 61  TYR   A CD2  1 
ATOM   1020 C  CD2  B TYR   A 1 61  ? 23.21415 -8.83692  2.18469   0.450 35.63006  ? 61  TYR   A CD2  1 
ATOM   1021 C  CE1  A TYR   A 1 61  ? 24.60932 -8.79097  2.43035   0.550 29.81444  ? 61  TYR   A CE1  1 
ATOM   1022 C  CE1  B TYR   A 1 61  ? 24.54557 -7.17001  3.92981   0.450 45.09553  ? 61  TYR   A CE1  1 
ATOM   1023 C  CE2  A TYR   A 1 61  ? 23.33860 -10.16484 0.93851   0.550 41.05315  ? 61  TYR   A CE2  1 
ATOM   1024 C  CE2  B TYR   A 1 61  ? 24.57741 -8.97362  2.35977   0.450 29.74120  ? 61  TYR   A CE2  1 
ATOM   1025 C  CZ   A TYR   A 1 61  ? 24.54935 -9.80109  1.49736   0.550 30.78969  ? 61  TYR   A CZ   1 
ATOM   1026 C  CZ   B TYR   A 1 61  ? 25.23607 -8.13097  3.23225   0.450 32.61614  ? 61  TYR   A CZ   1 
ATOM   1027 O  OH   A TYR   A 1 61  ? 25.70446 -10.45568 1.11394   0.550 36.90313  ? 61  TYR   A OH   1 
ATOM   1028 O  OH   B TYR   A 1 61  ? 26.58427 -8.24867  3.43121   0.450 27.38285  ? 61  TYR   A OH   1 
ATOM   1029 H  H    A TYR   A 1 61  ? 18.75541 -6.78502  2.46815   0.550 46.76159  ? 61  TYR   A H    1 
ATOM   1030 H  H    B TYR   A 1 61  ? 18.75973 -6.79066  2.46370   0.450 46.76159  ? 61  TYR   A H    1 
ATOM   1031 H  HA   A TYR   A 1 61  ? 21.18265 -5.78278  2.25350   0.550 45.09139  ? 61  TYR   A HA   1 
ATOM   1032 H  HA   B TYR   A 1 61  ? 21.15501 -5.72481  2.23777   0.450 45.32043  ? 61  TYR   A HA   1 
ATOM   1033 H  HB2  A TYR   A 1 61  ? 21.04754 -7.56036  3.62333   0.550 38.15869  ? 61  TYR   A HB2  1 
ATOM   1034 H  HB2  B TYR   A 1 61  ? 20.60396 -7.67742  3.57535   0.450 38.30276  ? 61  TYR   A HB2  1 
ATOM   1035 H  HB3  A TYR   A 1 61  ? 20.22094 -8.40736  2.56279   0.550 38.15869  ? 61  TYR   A HB3  1 
ATOM   1036 H  HB3  B TYR   A 1 61  ? 20.68922 -8.49954  2.21805   0.450 38.30276  ? 61  TYR   A HB3  1 
ATOM   1037 H  HD1  A TYR   A 1 61  ? 23.48934 -7.46913  3.45127   0.550 49.11992  ? 61  TYR   A HD1  1 
ATOM   1038 H  HD1  B TYR   A 1 61  ? 22.72681 -6.38795  4.22175   0.450 52.35882  ? 61  TYR   A HD1  1 
ATOM   1039 H  HD2  A TYR   A 1 61  ? 21.37460 -9.76325  0.94842   0.550 44.82595  ? 61  TYR   A HD2  1 
ATOM   1040 H  HD2  B TYR   A 1 61  ? 22.76884 -9.40014  1.59361   0.450 42.77035  ? 61  TYR   A HD2  1 
ATOM   1041 H  HE1  A TYR   A 1 61  ? 25.42579 -8.54483  2.80141   0.550 35.79160  ? 61  TYR   A HE1  1 
ATOM   1042 H  HE1  B TYR   A 1 61  ? 24.99367 -6.60881  4.52071   0.450 54.12891  ? 61  TYR   A HE1  1 
ATOM   1043 H  HE2  A TYR   A 1 61  ? 23.30104 -10.84629 0.30675   0.550 49.27805  ? 61  TYR   A HE2  1 
ATOM   1044 H  HE2  B TYR   A 1 61  ? 25.04716 -9.62737  1.89411   0.450 35.70372  ? 61  TYR   A HE2  1 
ATOM   1045 H  HH   A TYR   A 1 61  ? 26.35370 -10.18571 1.57350   0.550 44.29803  ? 61  TYR   A HH   1 
ATOM   1046 H  HH   B TYR   A 1 61  ? 26.90464 -8.81533  2.90030   0.450 32.87370  ? 61  TYR   A HH   1 
ATOM   1047 N  N    . ARG   A 1 62  ? 22.16385 -6.29073  0.07270   1.000 38.34717  ? 62  ARG   A N    1 
ATOM   1048 C  CA   . ARG   A 1 62  ? 22.74537 -6.47928  -1.24435  1.000 43.25841  ? 62  ARG   A CA   1 
ATOM   1049 C  C    . ARG   A 1 62  ? 24.19928 -6.86149  -0.97135  1.000 33.97375  ? 62  ARG   A C    1 
ATOM   1050 O  O    . ARG   A 1 62  ? 24.83531 -6.27086  -0.08471  1.000 39.15273  ? 62  ARG   A O    1 
ATOM   1051 C  CB   . ARG   A 1 62  ? 22.66888 -5.21303  -2.09809  1.000 52.46523  ? 62  ARG   A CB   1 
ATOM   1052 C  CG   . ARG   A 1 62  ? 23.63872 -5.19611  -3.27181  1.000 65.22431  ? 62  ARG   A CG   1 
ATOM   1053 C  CD   . ARG   A 1 62  ? 23.34966 -4.03653  -4.23054  1.000 47.87760  ? 62  ARG   A CD   1 
ATOM   1054 N  NE   . ARG   A 1 62  ? 24.02076 -4.23634  -5.51247  1.000 52.40864  ? 62  ARG   A NE   1 
ATOM   1055 C  CZ   . ARG   A 1 62  ? 24.85094 -3.36750  -6.07855  1.000 56.02327  ? 62  ARG   A CZ   1 
ATOM   1056 N  NH1  . ARG   A 1 62  ? 25.09106 -2.17984  -5.53989  1.000 64.30804  ? 62  ARG   A NH1  1 
ATOM   1057 N  NH2  . ARG   A 1 62  ? 25.45090 -3.69375  -7.22059  1.000 58.53239  ? 62  ARG   A NH2  1 
ATOM   1058 H  H    . ARG   A 1 62  ? 22.70678 -5.89228  0.60754   1.000 46.03088  ? 62  ARG   A H    1 
ATOM   1059 H  HA   . ARG   A 1 62  ? 22.29140 -7.17100  -1.75065  1.000 51.92436  ? 62  ARG   A HA   1 
ATOM   1060 H  HB2  . ARG   A 1 62  ? 21.77097 -5.13375  -2.45638  1.000 62.97255  ? 62  ARG   A HB2  1 
ATOM   1061 H  HB3  . ARG   A 1 62  ? 22.87113 -4.44773  -1.53744  1.000 62.97255  ? 62  ARG   A HB3  1 
ATOM   1062 H  HG2  . ARG   A 1 62  ? 24.54392 -5.09582  -2.93797  1.000 78.28344  ? 62  ARG   A HG2  1 
ATOM   1063 H  HG3  . ARG   A 1 62  ? 23.55761 -6.02661  -3.76637  1.000 78.28344  ? 62  ARG   A HG3  1 
ATOM   1064 H  HD2  . ARG   A 1 62  ? 22.39449 -3.97959  -4.38962  1.000 57.46740  ? 62  ARG   A HD2  1 
ATOM   1065 H  HD3  . ARG   A 1 62  ? 23.67117 -3.20817  -3.84151  1.000 57.46740  ? 62  ARG   A HD3  1 
ATOM   1066 H  HE   . ARG   A 1 62  ? 23.86695 -4.97117  -5.93195  1.000 62.90464  ? 62  ARG   A HE   1 
ATOM   1067 H  HH11 . ARG   A 1 62  ? 24.70506 -1.95501  -4.80500  1.000 77.18392  ? 62  ARG   A HH11 1 
ATOM   1068 H  HH12 . ARG   A 1 62  ? 25.63279 -1.63441  -5.92542  1.000 77.18392  ? 62  ARG   A HH12 1 
ATOM   1069 H  HH21 . ARG   A 1 62  ? 25.29910 -4.45885  -7.58278  1.000 70.25314  ? 62  ARG   A HH21 1 
ATOM   1070 H  HH22 . ARG   A 1 62  ? 25.99044 -3.13951  -7.59650  1.000 70.25314  ? 62  ARG   A HH22 1 
ATOM   1071 N  N    . PRO   A 1 63  ? 24.74310 -7.84407  -1.67735  1.000 35.56397  ? 63  PRO   A N    1 
ATOM   1072 C  CA   . PRO   A 1 63  ? 26.12679 -8.26571  -1.39121  1.000 30.91578  ? 63  PRO   A CA   1 
ATOM   1073 C  C    . PRO   A 1 63  ? 27.09661 -7.10321  -1.33043  1.000 36.30184  ? 63  PRO   A C    1 
ATOM   1074 O  O    . PRO   A 1 63  ? 27.21301 -6.31534  -2.27914  1.000 34.63603  ? 63  PRO   A O    1 
ATOM   1075 C  CB   . PRO   A 1 63  ? 26.44476 -9.21593  -2.55014  1.000 38.45536  ? 63  PRO   A CB   1 
ATOM   1076 C  CG   . PRO   A 1 63  ? 25.10804 -9.84308  -2.84414  1.000 33.02070  ? 63  PRO   A CG   1 
ATOM   1077 C  CD   . PRO   A 1 63  ? 24.08903 -8.74113  -2.64698  1.000 33.00604  ? 63  PRO   A CD   1 
ATOM   1078 H  HA   . PRO   A 1 63  ? 26.16666 -8.75244  -0.55312  1.000 37.11321  ? 63  PRO   A HA   1 
ATOM   1079 H  HB2  . PRO   A 1 63  ? 26.77960 -8.71957  -3.31330  1.000 46.16070  ? 63  PRO   A HB2  1 
ATOM   1080 H  HB3  . PRO   A 1 63  ? 27.09578 -9.88024  -2.27489  1.000 46.16070  ? 63  PRO   A HB3  1 
ATOM   1081 H  HG2  . PRO   A 1 63  ? 25.09179 -10.16779 -3.75803  1.000 39.63911  ? 63  PRO   A HG2  1 
ATOM   1082 H  HG3  . PRO   A 1 63  ? 24.94676 -10.57548 -2.22892  1.000 39.63911  ? 63  PRO   A HG3  1 
ATOM   1083 H  HD2  . PRO   A 1 63  ? 23.91454 -8.27889  -3.48173  1.000 39.62151  ? 63  PRO   A HD2  1 
ATOM   1084 H  HD3  . PRO   A 1 63  ? 23.26204 -9.09634  -2.28530  1.000 39.62151  ? 63  PRO   A HD3  1 
ATOM   1085 N  N    . MET   A 1 64  ? 27.79005 -6.98903  -0.19340  1.000 36.04776  ? 64  MET   A N    1 
ATOM   1086 C  CA   . MET   A 1 64  ? 28.74274 -5.89586  -0.02009  1.000 40.03398  ? 64  MET   A CA   1 
ATOM   1087 C  C    . MET   A 1 64  ? 29.85204 -5.95646  -1.05954  1.000 35.58015  ? 64  MET   A C    1 
ATOM   1088 O  O    . MET   A 1 64  ? 30.34993 -4.91445  -1.49670  1.000 35.60492  ? 64  MET   A O    1 
ATOM   1089 C  CB   . MET   A 1 64  ? 29.33650 -5.92148  1.38690   1.000 36.73981  ? 64  MET   A CB   1 
ATOM   1090 C  CG   . MET   A 1 64  ? 28.29246 -5.98837  2.47855   1.000 63.67551  ? 64  MET   A CG   1 
ATOM   1091 S  SD   . MET   A 1 64  ? 28.74111 -5.06238  3.96418   1.000 58.73026  ? 64  MET   A SD   1 
ATOM   1092 C  CE   . MET   A 1 64  ? 28.99294 -3.42764  3.27387   1.000 53.03649  ? 64  MET   A CE   1 
ATOM   1093 H  H    . MET   A 1 64  ? 27.72731 -7.52184  0.47875   1.000 43.27158  ? 64  MET   A H    1 
ATOM   1094 H  HA   . MET   A 1 64  ? 28.26407 -5.05793  -0.11833  1.000 48.05504  ? 64  MET   A HA   1 
ATOM   1095 H  HB2  . MET   A 1 64  ? 29.90649 -6.70171  1.47205   1.000 44.10204  ? 64  MET   A HB2  1 
ATOM   1096 H  HB3  . MET   A 1 64  ? 29.85690 -5.11411  1.52189   1.000 44.10204  ? 64  MET   A HB3  1 
ATOM   1097 H  HG2  . MET   A 1 64  ? 27.46122 -5.62082  2.13966   1.000 76.42488  ? 64  MET   A HG2  1 
ATOM   1098 H  HG3  . MET   A 1 64  ? 28.16553 -6.91550  2.73393   1.000 76.42488  ? 64  MET   A HG3  1 
ATOM   1099 H  HE1  . MET   A 1 64  ? 29.19734 -2.80932  3.99275   1.000 63.65806  ? 64  MET   A HE1  1 
ATOM   1100 H  HE2  . MET   A 1 64  ? 29.73139 -3.46040  2.64576   1.000 63.65806  ? 64  MET   A HE2  1 
ATOM   1101 H  HE3  . MET   A 1 64  ? 28.18321 -3.14909  2.81819   1.000 63.65806  ? 64  MET   A HE3  1 
ATOM   1102 N  N    . ARG   A 1 65  ? 30.26272 -7.15972  -1.45183  1.000 33.01971  ? 65  ARG   A N    1 
ATOM   1103 C  CA   . ARG   A 1 65  ? 31.29020 -7.27953  -2.47532  1.000 32.99447  ? 65  ARG   A CA   1 
ATOM   1104 C  C    . ARG   A 1 65  ? 30.81696 -6.69844  -3.79709  1.000 31.03103  ? 65  ARG   A C    1 
ATOM   1105 O  O    . ARG   A 1 65  ? 31.62019 -6.10742  -4.52908  1.000 33.44444  ? 65  ARG   A O    1 
ATOM   1106 C  CB   . ARG   A 1 65  ? 31.71141 -8.73555  -2.62405  1.000 30.47787  ? 65  ARG   A CB   1 
ATOM   1107 C  CG   . ARG   A 1 65  ? 32.45683 -9.27757  -1.38310  1.000 36.57343  ? 65  ARG   A CG   1 
ATOM   1108 C  CD   . ARG   A 1 65  ? 32.64548 -10.78814 -1.42628  1.000 30.32075  ? 65  ARG   A CD   1 
ATOM   1109 N  NE   . ARG   A 1 65  ? 31.37312 -11.47568 -1.23712  1.000 32.84425  ? 65  ARG   A NE   1 
ATOM   1110 C  CZ   . ARG   A 1 65  ? 31.20367 -12.78179 -1.36299  1.000 34.73100  ? 65  ARG   A CZ   1 
ATOM   1111 N  NH1  . ARG   A 1 65  ? 32.20735 -13.57725 -1.67496  1.000 35.44472  ? 65  ARG   A NH1  1 
ATOM   1112 N  NH2  . ARG   A 1 65  ? 29.99150 -13.30085 -1.17184  1.000 36.67192  ? 65  ARG   A NH2  1 
ATOM   1113 H  H    . ARG   A 1 65  ? 29.96734 -7.90736  -1.14624  1.000 39.63793  ? 65  ARG   A H    1 
ATOM   1114 H  HA   . ARG   A 1 65  ? 32.07761 -6.78234  -2.20386  1.000 39.60764  ? 65  ARG   A HA   1 
ATOM   1115 H  HB2  . ARG   A 1 65  ? 30.92011 -9.27996  -2.75958  1.000 36.58771  ? 65  ARG   A HB2  1 
ATOM   1116 H  HB3  . ARG   A 1 65  ? 32.30389 -8.81546  -3.38791  1.000 36.58771  ? 65  ARG   A HB3  1 
ATOM   1117 H  HG2  . ARG   A 1 65  ? 33.33430 -8.86682  -1.33593  1.000 43.90238  ? 65  ARG   A HG2  1 
ATOM   1118 H  HG3  . ARG   A 1 65  ? 31.94619 -9.06157  -0.58718  1.000 43.90238  ? 65  ARG   A HG3  1 
ATOM   1119 H  HD2  . ARG   A 1 65  ? 33.00863 -11.04438 -2.28846  1.000 36.39917  ? 65  ARG   A HD2  1 
ATOM   1120 H  HD3  . ARG   A 1 65  ? 33.25010 -11.05912 -0.71783  1.000 36.39917  ? 65  ARG   A HD3  1 
ATOM   1121 H  HE   . ARG   A 1 65  ? 30.68711 -11.00024 -1.02989  1.000 39.42737  ? 65  ARG   A HE   1 
ATOM   1122 H  HH11 . ARG   A 1 65  ? 32.99242 -13.24968 -1.80125  1.000 42.54794  ? 65  ARG   A HH11 1 
ATOM   1123 H  HH12 . ARG   A 1 65  ? 32.07711 -14.42382 -1.75221  1.000 42.54794  ? 65  ARG   A HH12 1 
ATOM   1124 H  HH21 . ARG   A 1 65  ? 29.33129 -12.78828 -0.96935  1.000 44.02058  ? 65  ARG   A HH21 1 
ATOM   1125 H  HH22 . ARG   A 1 65  ? 29.86931 -14.14844 -1.25095  1.000 44.02058  ? 65  ARG   A HH22 1 
ATOM   1126 N  N    . ASP   A 1 66  ? 29.52174 -6.82933  -4.10834  1.000 31.45928  ? 66  ASP   A N    1 
ATOM   1127 C  CA   . ASP   A 1 66  ? 28.99454 -6.21261  -5.32188  1.000 35.20235  ? 66  ASP   A CA   1 
ATOM   1128 C  C    . ASP   A 1 66  ? 29.03076 -4.69507  -5.20991  1.000 34.00475  ? 66  ASP   A C    1 
ATOM   1129 O  O    . ASP   A 1 66  ? 29.33233 -4.00703  -6.18720  1.000 32.13103  ? 66  ASP   A O    1 
ATOM   1130 C  CB   . ASP   A 1 66  ? 27.56141 -6.67794  -5.59819  1.000 37.31955  ? 66  ASP   A CB   1 
ATOM   1131 C  CG   . ASP   A 1 66  ? 27.46865 -8.17139  -5.93020  1.000 35.58131  ? 66  ASP   A CG   1 
ATOM   1132 O  OD1  . ASP   A 1 66  ? 28.50543 -8.83863  -6.03679  1.000 40.19899  ? 66  ASP   A OD1  1 
ATOM   1133 O  OD2  . ASP   A 1 66  ? 26.33831 -8.67348  -6.06137  1.000 43.11909  ? 66  ASP   A OD2  1 
ATOM   1134 H  H    . ASP   A 1 66  ? 28.94250 -7.26122  -3.64192  1.000 37.76540  ? 66  ASP   A H    1 
ATOM   1135 H  HA   . ASP   A 1 66  ? 29.54453 -6.49384  -6.06975  1.000 42.25709  ? 66  ASP   A HA   1 
ATOM   1136 H  HB2  . ASP   A 1 66  ? 27.01934 -6.51277  -4.81093  1.000 44.79774  ? 66  ASP   A HB2  1 
ATOM   1137 H  HB3  . ASP   A 1 66  ? 27.20925 -6.18163  -6.35356  1.000 44.79774  ? 66  ASP   A HB3  1 
ATOM   1138 N  N    . ILE   A 1 67  ? 28.71213 -4.15888  -4.02930  1.000 35.04276  ? 67  ILE   A N    1 
ATOM   1139 C  CA   . ILE   A 1 67  ? 28.73404 -2.71301  -3.82953  1.000 32.36126  ? 67  ILE   A CA   1 
ATOM   1140 C  C    . ILE   A 1 67  ? 30.15098 -2.17718  -3.97937  1.000 36.12175  ? 67  ILE   A C    1 
ATOM   1141 O  O    . ILE   A 1 67  ? 30.39166 -1.16298  -4.64973  1.000 33.18912  ? 67  ILE   A O    1 
ATOM   1142 C  CB   . ILE   A 1 67  ? 28.15229 -2.35918  -2.44804  1.000 36.07445  ? 67  ILE   A CB   1 
ATOM   1143 C  CG1  . ILE   A 1 67  ? 26.66709 -2.73308  -2.37769  1.000 40.94634  ? 67  ILE   A CG1  1 
ATOM   1144 C  CG2  . ILE   A 1 67  ? 28.35065 -0.87762  -2.13955  1.000 43.43231  ? 67  ILE   A CG2  1 
ATOM   1145 C  CD1  . ILE   A 1 67  ? 26.11161 -2.71568  -0.96238  1.000 45.04634  ? 67  ILE   A CD1  1 
ATOM   1146 H  H    . ILE   A 1 67  ? 28.48152 -4.60880  -3.33361  1.000 42.06558  ? 67  ILE   A H    1 
ATOM   1147 H  HA   . ILE   A 1 67  ? 28.18168 -2.30022  -4.51173  1.000 38.84778  ? 67  ILE   A HA   1 
ATOM   1148 H  HB   . ILE   A 1 67  ? 28.62977 -2.87493  -1.77953  1.000 43.30361  ? 67  ILE   A HB   1 
ATOM   1149 H  HG12 . ILE   A 1 67  ? 26.15809 -2.09841  -2.90590  1.000 49.14988  ? 67  ILE   A HG12 1 
ATOM   1150 H  HG13 . ILE   A 1 67  ? 26.55145 -3.62834  -2.73271  1.000 49.14988  ? 67  ILE   A HG13 1 
ATOM   1151 H  HG21 . ILE   A 1 67  ? 27.80424 -0.63841  -1.37462  1.000 52.13305  ? 67  ILE   A HG21 1 
ATOM   1152 H  HG22 . ILE   A 1 67  ? 29.28658 -0.71914  -1.94001  1.000 52.13305  ? 67  ILE   A HG22 1 
ATOM   1153 H  HG23 . ILE   A 1 67  ? 28.08424 -0.35567  -2.91253  1.000 52.13305  ? 67  ILE   A HG23 1 
ATOM   1154 H  HD11 . ILE   A 1 67  ? 25.25206 -3.16513  -0.95493  1.000 54.06988  ? 67  ILE   A HD11 1 
ATOM   1155 H  HD12 . ILE   A 1 67  ? 26.73072 -3.17607  -0.37446  1.000 54.06988  ? 67  ILE   A HD12 1 
ATOM   1156 H  HD13 . ILE   A 1 67  ? 26.00595 -1.79500  -0.67589  1.000 54.06988  ? 67  ILE   A HD13 1 
ATOM   1157 N  N    . LEU   A 1 68  ? 31.11201 -2.85203  -3.36278  1.000 31.71081  ? 68  LEU   A N    1 
ATOM   1158 C  CA   . LEU   A 1 68  ? 32.48864 -2.36792  -3.40239  1.000 32.38207  ? 68  LEU   A CA   1 
ATOM   1159 C  C    . LEU   A 1 68  ? 33.10491 -2.55125  -4.77950  1.000 38.11825  ? 68  LEU   A C    1 
ATOM   1160 O  O    . LEU   A 1 68  ? 33.95144 -1.75158  -5.19549  1.000 34.33593  ? 68  LEU   A O    1 
ATOM   1161 C  CB   . LEU   A 1 68  ? 33.32666 -3.06971  -2.34143  1.000 34.46102  ? 68  LEU   A CB   1 
ATOM   1162 C  CG   . LEU   A 1 68  ? 32.88785 -2.75588  -0.90092  1.000 35.19653  ? 68  LEU   A CG   1 
ATOM   1163 C  CD1  . LEU   A 1 68  ? 33.61785 -3.62063  0.10525   1.000 42.77692  ? 68  LEU   A CD1  1 
ATOM   1164 C  CD2  . LEU   A 1 68  ? 33.10244 -1.27801  -0.57422  1.000 36.42460  ? 68  LEU   A CD2  1 
ATOM   1165 H  H    . LEU   A 1 68  ? 30.99855 -3.58117  -2.92110  1.000 38.06725  ? 68  LEU   A H    1 
ATOM   1166 H  HA   . LEU   A 1 68  ? 32.49185 -1.41969  -3.19803  1.000 38.87276  ? 68  LEU   A HA   1 
ATOM   1167 H  HB2  . LEU   A 1 68  ? 33.25518 -4.02826  -2.47173  1.000 41.36750  ? 68  LEU   A HB2  1 
ATOM   1168 H  HB3  . LEU   A 1 68  ? 34.25028 -2.78967  -2.43844  1.000 41.36750  ? 68  LEU   A HB3  1 
ATOM   1169 H  HG   . LEU   A 1 68  ? 31.94073 -2.95308  -0.83035  1.000 42.25011  ? 68  LEU   A HG   1 
ATOM   1170 H  HD11 . LEU   A 1 68  ? 33.23922 -3.46921  0.98537   1.000 51.34657  ? 68  LEU   A HD11 1 
ATOM   1171 H  HD12 . LEU   A 1 68  ? 33.51312 -4.55217  -0.14409  1.000 51.34657  ? 68  LEU   A HD12 1 
ATOM   1172 H  HD13 . LEU   A 1 68  ? 34.55792 -3.38154  0.10398   1.000 51.34657  ? 68  LEU   A HD13 1 
ATOM   1173 H  HD21 . LEU   A 1 68  ? 33.12956 -1.16826  0.38917   1.000 43.72380  ? 68  LEU   A HD21 1 
ATOM   1174 H  HD22 . LEU   A 1 68  ? 33.94166 -0.98704  -0.96404  1.000 43.72380  ? 68  LEU   A HD22 1 
ATOM   1175 H  HD23 . LEU   A 1 68  ? 32.36911 -0.76283  -0.94532  1.000 43.72380  ? 68  LEU   A HD23 1 
ATOM   1176 N  N    . GLU   A 1 69  ? 32.69357 -3.58211  -5.50993  1.000 36.88205  ? 69  GLU   A N    1 
ATOM   1177 C  CA   . GLU   A 1 69  ? 33.17759 -3.73488  -6.88124  1.000 33.44834  ? 69  GLU   A CA   1 
ATOM   1178 C  C    . GLU   A 1 69  ? 32.63464 -2.62901  -7.77863  1.000 38.72403  ? 69  GLU   A C    1 
ATOM   1179 O  O    . GLU   A 1 69  ? 33.34984 -2.13614  -8.65749  1.000 34.05370  ? 69  GLU   A O    1 
ATOM   1180 C  CB   . GLU   A 1 69  ? 32.82236 -5.12828  -7.40823  1.000 40.35151  ? 69  GLU   A CB   1 
ATOM   1181 C  CG   . GLU   A 1 69  ? 33.76591 -6.19782  -6.83890  1.000 39.76709  ? 69  GLU   A CG   1 
ATOM   1182 C  CD   . GLU   A 1 69  ? 33.43215 -7.61091  -7.27399  1.000 50.23655  ? 69  GLU   A CD   1 
ATOM   1183 O  OE1  . GLU   A 1 69  ? 32.28779 -7.85893  -7.68714  1.000 43.16278  ? 69  GLU   A OE1  1 
ATOM   1184 O  OE2  . GLU   A 1 69  ? 34.32603 -8.47652  -7.17461  1.000 52.17124  ? 69  GLU   A OE2  1 
ATOM   1185 H  H    . GLU   A 1 69  ? 32.14896 -4.19267  -5.24496  1.000 44.27273  ? 69  GLU   A H    1 
ATOM   1186 H  HA   . GLU   A 1 69  ? 34.14497 -3.66483  -6.89408  1.000 40.15228  ? 69  GLU   A HA   1 
ATOM   1187 H  HB2  . GLU   A 1 69  ? 31.91499 -5.34915  -7.14595  1.000 48.43608  ? 69  GLU   A HB2  1 
ATOM   1188 H  HB3  . GLU   A 1 69  ? 32.89921 -5.13518  -8.37515  1.000 48.43608  ? 69  GLU   A HB3  1 
ATOM   1189 H  HG2  . GLU   A 1 69  ? 34.66946 -6.00454  -7.13409  1.000 47.73477  ? 69  GLU   A HG2  1 
ATOM   1190 H  HG3  . GLU   A 1 69  ? 33.72008 -6.16940  -5.87040  1.000 47.73477  ? 69  GLU   A HG3  1 
ATOM   1191 N  N    . GLU   A 1 70  ? 31.39434 -2.19410  -7.55196  1.000 35.71965  ? 70  GLU   A N    1 
ATOM   1192 C  CA   . GLU   A 1 70  ? 30.88761 -1.01753  -8.25786  1.000 38.65205  ? 70  GLU   A CA   1 
ATOM   1193 C  C    . GLU   A 1 70  ? 31.73937 0.21252   -7.95256  1.000 39.49473  ? 70  GLU   A C    1 
ATOM   1194 O  O    . GLU   A 1 70  ? 32.09808 0.97911   -8.85314  1.000 38.30673  ? 70  GLU   A O    1 
ATOM   1195 C  CB   . GLU   A 1 70  ? 29.43637 -0.73377  -7.87588  1.000 45.94909  ? 70  GLU   A CB   1 
ATOM   1196 C  CG   . GLU   A 1 70  ? 28.38328 -1.51350  -8.62146  1.000 63.04977  ? 70  GLU   A CG   1 
ATOM   1197 C  CD   . GLU   A 1 70  ? 26.97986 -1.03741  -8.26597  1.000 73.91017  ? 70  GLU   A CD   1 
ATOM   1198 O  OE1  . GLU   A 1 70  ? 26.84223 -0.25861  -7.28934  1.000 59.37588  ? 70  GLU   A OE1  1 
ATOM   1199 O  OE2  . GLU   A 1 70  ? 26.01790 -1.44063  -8.95570  1.000 65.98099  ? 70  GLU   A OE2  1 
ATOM   1200 H  H    . GLU   A 1 70  ? 30.83678 -2.55475  -7.00546  1.000 42.87785  ? 70  GLU   A H    1 
ATOM   1201 H  HA   . GLU   A 1 70  ? 30.92208 -1.20599  -9.20876  1.000 46.39673  ? 70  GLU   A HA   1 
ATOM   1202 H  HB2  . GLU   A 1 70  ? 29.32730 -0.93650  -6.93359  1.000 55.15318  ? 70  GLU   A HB2  1 
ATOM   1203 H  HB3  . GLU   A 1 70  ? 29.26084 0.20679   -8.03536  1.000 55.15318  ? 70  GLU   A HB3  1 
ATOM   1204 H  HG2  . GLU   A 1 70  ? 28.51277 -1.39657  -9.57564  1.000 75.67400  ? 70  GLU   A HG2  1 
ATOM   1205 H  HG3  . GLU   A 1 70  ? 28.45496 -2.45264  -8.38956  1.000 75.67400  ? 70  GLU   A HG3  1 
ATOM   1206 N  N    . VAL   A 1 71  ? 32.05207 0.42768   -6.67848  1.000 33.00424  ? 71  VAL   A N    1 
ATOM   1207 C  CA   . VAL   A 1 71  ? 32.89530 1.56217   -6.29822  1.000 34.07775  ? 71  VAL   A CA   1 
ATOM   1208 C  C    . VAL   A 1 71  ? 34.23371 1.49980   -7.02584  1.000 35.09510  ? 71  VAL   A C    1 
ATOM   1209 O  O    . VAL   A 1 71  ? 34.72770 2.50816   -7.54572  1.000 31.57232  ? 71  VAL   A O    1 
ATOM   1210 C  CB   . VAL   A 1 71  ? 33.09225 1.60397   -4.77562  1.000 34.48537  ? 71  VAL   A CB   1 
ATOM   1211 C  CG1  . VAL   A 1 71  ? 34.24543 2.52097   -4.42603  1.000 37.00148  ? 71  VAL   A CG1  1 
ATOM   1212 C  CG2  . VAL   A 1 71  ? 31.81869 2.05179   -4.09071  1.000 40.48370  ? 71  VAL   A CG2  1 
ATOM   1213 H  H    . VAL   A 1 71  ? 31.79331 -0.06110  -6.01990  1.000 39.61935  ? 71  VAL   A H    1 
ATOM   1214 H  HA   . VAL   A 1 71  ? 32.44354 2.37760   -6.56634  1.000 40.90757  ? 71  VAL   A HA   1 
ATOM   1215 H  HB   . VAL   A 1 71  ? 33.30502 0.71359   -4.45490  1.000 41.39671  ? 71  VAL   A HB   1 
ATOM   1216 H  HG11 . VAL   A 1 71  ? 34.17682 2.77253   -3.49173  1.000 44.41605  ? 71  VAL   A HG11 1 
ATOM   1217 H  HG12 . VAL   A 1 71  ? 35.08017 2.05214   -4.58191  1.000 44.41605  ? 71  VAL   A HG12 1 
ATOM   1218 H  HG13 . VAL   A 1 71  ? 34.20079 3.31196   -4.98570  1.000 44.41605  ? 71  VAL   A HG13 1 
ATOM   1219 H  HG21 . VAL   A 1 71  ? 31.95325 2.03307   -3.13027  1.000 48.59471  ? 71  VAL   A HG21 1 
ATOM   1220 H  HG22 . VAL   A 1 71  ? 31.60628 2.95377   -4.37744  1.000 48.59471  ? 71  VAL   A HG22 1 
ATOM   1221 H  HG23 . VAL   A 1 71  ? 31.09950 1.44879   -4.33578  1.000 48.59471  ? 71  VAL   A HG23 1 
ATOM   1222 N  N    . MET   A 1 72  ? 34.85327 0.32104   -7.05935  1.000 31.70183  ? 72  MET   A N    1 
ATOM   1223 C  CA   . MET   A 1 72  ? 36.15318 0.20595   -7.71617  1.000 30.46341  ? 72  MET   A CA   1 
ATOM   1224 C  C    . MET   A 1 72  ? 36.04014 0.46189   -9.20803  1.000 28.68696  ? 72  MET   A C    1 
ATOM   1225 O  O    . MET   A 1 72  ? 36.98666 0.98670   -9.81487  1.000 34.06961  ? 72  MET   A O    1 
ATOM   1226 C  CB   . MET   A 1 72  ? 36.76575 -1.16891  -7.45048  1.000 28.66683  ? 72  MET   A CB   1 
ATOM   1227 C  CG   . MET   A 1 72  ? 38.15184 -1.35179  -8.03584  1.000 28.75621  ? 72  MET   A CG   1 
ATOM   1228 S  SD   . MET   A 1 72  ? 39.39711 -0.20790  -7.43666  1.000 35.59398  ? 72  MET   A SD   1 
ATOM   1229 C  CE   . MET   A 1 72  ? 39.54766 -0.68827  -5.74361  1.000 46.15634  ? 72  MET   A CE   1 
ATOM   1230 H  H    . MET   A 1 72  ? 34.55107 -0.40843  -6.71856  1.000 38.05646  ? 72  MET   A H    1 
ATOM   1231 H  HA   . MET   A 1 72  ? 36.75280 0.86415   -7.33129  1.000 36.57036  ? 72  MET   A HA   1 
ATOM   1232 H  HB2  . MET   A 1 72  ? 36.83109 -1.29974  -6.49157  1.000 34.41447  ? 72  MET   A HB2  1 
ATOM   1233 H  HB3  . MET   A 1 72  ? 36.18992 -1.84584  -7.83920  1.000 34.41447  ? 72  MET   A HB3  1 
ATOM   1234 H  HG2  . MET   A 1 72  ? 38.45735 -2.24782  -7.82445  1.000 34.52172  ? 72  MET   A HG2  1 
ATOM   1235 H  HG3  . MET   A 1 72  ? 38.09504 -1.23891  -8.99758  1.000 34.52172  ? 72  MET   A HG3  1 
ATOM   1236 H  HE1  . MET   A 1 72  ? 40.22488 -0.13909  -5.31854  1.000 55.40188  ? 72  MET   A HE1  1 
ATOM   1237 H  HE2  . MET   A 1 72  ? 38.69343 -0.56089  -5.30204  1.000 55.40188  ? 72  MET   A HE2  1 
ATOM   1238 H  HE3  . MET   A 1 72  ? 39.80541 -1.62247  -5.70212  1.000 55.40188  ? 72  MET   A HE3  1 
ATOM   1239 N  N    A ARG   A 1 73  ? 34.91243 0.08377   -9.81830  0.480 30.74519  ? 73  ARG   A N    1 
ATOM   1240 N  N    B ARG   A 1 73  ? 34.90726 0.10470   -9.82266  0.520 30.72349  ? 73  ARG   A N    1 
ATOM   1241 C  CA   A ARG   A 1 73  ? 34.69487 0.37818   -11.23157 0.480 36.17654  ? 73  ARG   A CA   1 
ATOM   1242 C  CA   B ARG   A 1 73  ? 34.72442 0.38552   -11.24471 0.520 36.13066  ? 73  ARG   A CA   1 
ATOM   1243 C  C    A ARG   A 1 73  ? 34.72296 1.87938   -11.48043 0.480 34.96085  ? 73  ARG   A C    1 
ATOM   1244 C  C    B ARG   A 1 73  ? 34.69279 1.88529   -11.50807 0.520 34.88923  ? 73  ARG   A C    1 
ATOM   1245 O  O    A ARG   A 1 73  ? 35.33449 2.34813   -12.44864 0.480 30.75019  ? 73  ARG   A O    1 
ATOM   1246 O  O    B ARG   A 1 73  ? 35.22426 2.35854   -12.52086 0.520 30.10404  ? 73  ARG   A O    1 
ATOM   1247 C  CB   A ARG   A 1 73  ? 33.35600 -0.20828  -11.68715 0.480 35.81135  ? 73  ARG   A CB   1 
ATOM   1248 C  CB   B ARG   A 1 73  ? 33.43934 -0.26501  -11.75938 0.520 36.05746  ? 73  ARG   A CB   1 
ATOM   1249 C  CG   A ARG   A 1 73  ? 33.35586 -0.79904  -13.09036 0.480 60.66873  ? 73  ARG   A CG   1 
ATOM   1250 C  CG   B ARG   A 1 73  ? 33.58753 -1.74709  -12.05595 0.520 33.73842  ? 73  ARG   A CG   1 
ATOM   1251 C  CD   A ARG   A 1 73  ? 33.01538 -2.28968  -13.04433 0.480 64.88102  ? 73  ARG   A CD   1 
ATOM   1252 C  CD   B ARG   A 1 73  ? 32.45767 -2.25767  -12.94841 0.520 62.70710  ? 73  ARG   A CD   1 
ATOM   1253 N  NE   A ARG   A 1 73  ? 31.78995 -2.53713  -12.29134 0.480 51.96094  ? 73  ARG   A NE   1 
ATOM   1254 N  NE   B ARG   A 1 73  ? 32.73560 -3.60211  -13.43969 0.520 45.76150  ? 73  ARG   A NE   1 
ATOM   1255 C  CZ   A ARG   A 1 73  ? 31.51761 -3.66094  -11.64079 0.480 52.97829  ? 73  ARG   A CZ   1 
ATOM   1256 C  CZ   B ARG   A 1 73  ? 33.51062 -3.87213  -14.48146 0.520 48.65972  ? 73  ARG   A CZ   1 
ATOM   1257 N  NH1  A ARG   A 1 73  ? 32.36015 -4.68110  -11.63846 0.480 45.71396  ? 73  ARG   A NH1  1 
ATOM   1258 N  NH1  B ARG   A 1 73  ? 34.10942 -2.91176  -15.16544 0.520 49.83574  ? 73  ARG   A NH1  1 
ATOM   1259 N  NH2  A ARG   A 1 73  ? 30.37170 -3.76028  -10.97252 0.480 29.15326  ? 73  ARG   A NH2  1 
ATOM   1260 N  NH2  B ARG   A 1 73  ? 33.69240 -5.13820  -14.84363 0.520 48.52206  ? 73  ARG   A NH2  1 
ATOM   1261 H  H    A ARG   A 1 73  ? 34.26671 -0.33929  -9.43927  0.480 36.90850  ? 73  ARG   A H    1 
ATOM   1262 H  H    B ARG   A 1 73  ? 34.24452 -0.29280  -9.44534  0.520 36.88246  ? 73  ARG   A H    1 
ATOM   1263 H  HA   A ARG   A 1 73  ? 35.40042 -0.03485  -11.75359 0.480 43.42612  ? 73  ARG   A HA   1 
ATOM   1264 H  HA   B ARG   A 1 73  ? 35.47075 0.00122   -11.73073 0.520 43.37106  ? 73  ARG   A HA   1 
ATOM   1265 H  HB2  A ARG   A 1 73  ? 33.10657 -0.91679  -11.07339 0.480 42.98789  ? 73  ARG   A HB2  1 
ATOM   1266 H  HB2  B ARG   A 1 73  ? 32.74693 -0.16410  -11.08759 0.520 43.28322  ? 73  ARG   A HB2  1 
ATOM   1267 H  HB3  A ARG   A 1 73  ? 32.68993 0.49663   -11.66841 0.480 42.98789  ? 73  ARG   A HB3  1 
ATOM   1268 H  HB3  B ARG   A 1 73  ? 33.17204 0.17711   -12.58034 0.520 43.28322  ? 73  ARG   A HB3  1 
ATOM   1269 H  HG2  A ARG   A 1 73  ? 32.69131 -0.34691  -13.63334 0.480 72.81675  ? 73  ARG   A HG2  1 
ATOM   1270 H  HG2  B ARG   A 1 73  ? 34.42933 -1.90035  -12.51287 0.520 40.50038  ? 73  ARG   A HG2  1 
ATOM   1271 H  HG3  A ARG   A 1 73  ? 34.23495 -0.69498  -13.48695 0.480 72.81675  ? 73  ARG   A HG3  1 
ATOM   1272 H  HG3  B ARG   A 1 73  ? 33.56649 -2.24463  -11.22354 0.520 40.50038  ? 73  ARG   A HG3  1 
ATOM   1273 H  HD2  A ARG   A 1 73  ? 32.88917 -2.61800  -13.94831 0.480 77.87150  ? 73  ARG   A HD2  1 
ATOM   1274 H  HD2  B ARG   A 1 73  ? 31.63218 -2.28267  -12.43965 0.520 75.26279  ? 73  ARG   A HD2  1 
ATOM   1275 H  HD3  A ARG   A 1 73  ? 33.73960 -2.77107  -12.61461 0.480 77.87150  ? 73  ARG   A HD3  1 
ATOM   1276 H  HD3  B ARG   A 1 73  ? 32.35910 -1.66750  -13.71188 0.520 75.26279  ? 73  ARG   A HD3  1 
ATOM   1277 H  HE   A ARG   A 1 73  ? 31.20234 -1.90963  -12.26760 0.480 62.36740  ? 73  ARG   A HE   1 
ATOM   1278 H  HE   B ARG   A 1 73  ? 32.37303 -4.26359  -13.02666 0.520 54.92807  ? 73  ARG   A HE   1 
ATOM   1279 H  HH11 A ARG   A 1 73  ? 33.10457 -4.62496  -12.06543 0.480 54.87102  ? 73  ARG   A HH11 1 
ATOM   1280 H  HH11 B ARG   A 1 73  ? 34.00044 -2.08961  -14.93784 0.520 59.81716  ? 73  ARG   A HH11 1 
ATOM   1281 H  HH12 A ARG   A 1 73  ? 32.16339 -5.40033  -11.20998 0.480 54.87102  ? 73  ARG   A HH12 1 
ATOM   1282 H  HH12 B ARG   A 1 73  ? 34.60783 -3.10933  -15.83787 0.520 59.81716  ? 73  ARG   A HH12 1 
ATOM   1283 H  HH21 A ARG   A 1 73  ? 29.81910 -3.10135  -10.96617 0.480 34.99818  ? 73  ARG   A HH21 1 
ATOM   1284 H  HH21 B ARG   A 1 73  ? 33.30953 -5.77043  -14.40398 0.520 58.24075  ? 73  ARG   A HH21 1 
ATOM   1285 H  HH22 A ARG   A 1 73  ? 30.18348 -4.48344  -10.54683 0.480 34.99818  ? 73  ARG   A HH22 1 
ATOM   1286 H  HH22 B ARG   A 1 73  ? 34.19288 -5.32504  -15.51758 0.520 58.24075  ? 73  ARG   A HH22 1 
ATOM   1287 N  N    . LYS   A 1 74  ? 34.06365 2.64835   -10.61177 1.000 31.88044  ? 74  LYS   A N    1 
ATOM   1288 C  CA   . LYS   A 1 74  ? 34.06259 4.09977   -10.75418 1.000 33.67465  ? 74  LYS   A CA   1 
ATOM   1289 C  C    . LYS   A 1 74  ? 35.46279 4.66459   -10.56666 1.000 32.39164  ? 74  LYS   A C    1 
ATOM   1290 O  O    . LYS   A 1 74  ? 35.85490 5.61119   -11.25770 1.000 32.82978  ? 74  LYS   A O    1 
ATOM   1291 C  CB   . LYS   A 1 74  ? 33.09426 4.72729   -9.74504  1.000 43.84407  ? 74  LYS   A CB   1 
ATOM   1292 C  CG   . LYS   A 1 74  ? 31.64147 4.41327   -10.03104 1.000 45.23556  ? 74  LYS   A CG   1 
ATOM   1293 C  CD   . LYS   A 1 74  ? 30.72152 4.90737   -8.91626  1.000 66.54217  ? 74  LYS   A CD   1 
ATOM   1294 C  CE   . LYS   A 1 74  ? 29.28770 4.41735   -9.14344  1.000 75.80012  ? 74  LYS   A CE   1 
ATOM   1295 N  NZ   . LYS   A 1 74  ? 28.34635 4.89679   -8.09574  1.000 79.79710  ? 74  LYS   A NZ   1 
ATOM   1296 H  H    A LYS   A 1 74  ? 33.61452 2.35614   -9.93909  0.480 38.27080  ? 74  LYS   A H    1 
ATOM   1297 H  H    B LYS   A 1 74  ? 33.63802 2.35392   -9.92493  0.520 38.27080  ? 74  LYS   A H    1 
ATOM   1298 H  HA   . LYS   A 1 74  ? 33.75678 4.32794   -11.64599 1.000 40.42385  ? 74  LYS   A HA   1 
ATOM   1299 H  HB2  . LYS   A 1 74  ? 33.30291 4.39050   -8.85963  1.000 52.62716  ? 74  LYS   A HB2  1 
ATOM   1300 H  HB3  . LYS   A 1 74  ? 33.20037 5.69122   -9.76685  1.000 52.62716  ? 74  LYS   A HB3  1 
ATOM   1301 H  HG2  . LYS   A 1 74  ? 31.37707 4.84759   -10.85709 1.000 54.29694  ? 74  LYS   A HG2  1 
ATOM   1302 H  HG3  . LYS   A 1 74  ? 31.53171 3.45285   -10.11130 1.000 54.29694  ? 74  LYS   A HG3  1 
ATOM   1303 H  HD2  . LYS   A 1 74  ? 31.03276 4.56615   -8.06327  1.000 79.86488  ? 74  LYS   A HD2  1 
ATOM   1304 H  HD3  . LYS   A 1 74  ? 30.71791 5.87729   -8.90421  1.000 79.86488  ? 74  LYS   A HD3  1 
ATOM   1305 H  HE2  . LYS   A 1 74  ? 28.97362 4.74340   -10.00131 1.000 90.97442  ? 74  LYS   A HE2  1 
ATOM   1306 H  HE3  . LYS   A 1 74  ? 29.27908 3.44743   -9.13380  1.000 90.97442  ? 74  LYS   A HE3  1 
ATOM   1307 H  HZ1  . LYS   A 1 74  ? 27.52944 4.58033   -8.25264  1.000 95.77079  ? 74  LYS   A HZ1  1 
ATOM   1308 H  HZ2  . LYS   A 1 74  ? 28.61511 4.61800   -7.29440  1.000 95.77079  ? 74  LYS   A HZ2  1 
ATOM   1309 H  HZ3  . LYS   A 1 74  ? 28.31672 5.78629   -8.09714  1.000 95.77079  ? 74  LYS   A HZ3  1 
ATOM   1310 N  N    . LEU   A 1 75  ? 36.23852 4.08000   -9.65593  1.000 29.04148  ? 75  LEU   A N    1 
ATOM   1311 C  CA   . LEU   A 1 75  ? 37.60167 4.55587   -9.42498  1.000 32.35483  ? 75  LEU   A CA   1 
ATOM   1312 C  C    . LEU   A 1 75  ? 38.48527 4.26253   -10.63107 1.000 31.55744  ? 75  LEU   A C    1 
ATOM   1313 O  O    . LEU   A 1 75  ? 39.30016 5.09884   -11.03170 1.000 28.60628  ? 75  LEU   A O    1 
ATOM   1314 C  CB   . LEU   A 1 75  ? 38.18304 3.91379   -8.17352  1.000 30.79162  ? 75  LEU   A CB   1 
ATOM   1315 C  CG   . LEU   A 1 75  ? 37.53380 4.31645   -6.84851  1.000 32.35012  ? 75  LEU   A CG   1 
ATOM   1316 C  CD1  . LEU   A 1 75  ? 38.00304 3.40619   -5.71176  1.000 42.28285  ? 75  LEU   A CD1  1 
ATOM   1317 C  CD2  . LEU   A 1 75  ? 37.80735 5.75792   -6.52811  1.000 32.96641  ? 75  LEU   A CD2  1 
ATOM   1318 H  H    . LEU   A 1 75  ? 36.00419 3.41465   -9.16400  1.000 34.86404  ? 75  LEU   A H    1 
ATOM   1319 H  HA   . LEU   A 1 75  ? 37.57919 5.51497   -9.28175  1.000 38.84007  ? 75  LEU   A HA   1 
ATOM   1320 H  HB2  . LEU   A 1 75  ? 38.09173 2.95173   -8.25718  1.000 36.96422  ? 75  LEU   A HB2  1 
ATOM   1321 H  HB3  . LEU   A 1 75  ? 39.12109 4.15445   -8.11830  1.000 36.96422  ? 75  LEU   A HB3  1 
ATOM   1322 H  HG   . LEU   A 1 75  ? 36.57310 4.21283   -6.93349  1.000 38.83441  ? 75  LEU   A HG   1 
ATOM   1323 H  HD11 . LEU   A 1 75  ? 37.44823 3.56343   -4.93178  1.000 50.75369  ? 75  LEU   A HD11 1 
ATOM   1324 H  HD12 . LEU   A 1 75  ? 37.92268 2.48162   -5.99389  1.000 50.75369  ? 75  LEU   A HD12 1 
ATOM   1325 H  HD13 . LEU   A 1 75  ? 38.92875 3.60989   -5.50572  1.000 50.75369  ? 75  LEU   A HD13 1 
ATOM   1326 H  HD21 . LEU   A 1 75  ? 37.51644 5.94051   -5.62095  1.000 39.57396  ? 75  LEU   A HD21 1 
ATOM   1327 H  HD22 . LEU   A 1 75  ? 38.75944 5.92445   -6.60999  1.000 39.57396  ? 75  LEU   A HD22 1 
ATOM   1328 H  HD23 . LEU   A 1 75  ? 37.31876 6.31816   -7.15125  1.000 39.57396  ? 75  LEU   A HD23 1 
ATOM   1329 N  N    . ALA   A 1 76  ? 38.35592 3.07062   -11.20718 1.000 28.40939  ? 76  ALA   A N    1 
ATOM   1330 C  CA   . ALA   A 1 76  ? 39.11990 2.74212   -12.40344 1.000 30.08125  ? 76  ALA   A CA   1 
ATOM   1331 C  C    . ALA   A 1 76  ? 38.81210 3.73316   -13.52145 1.000 33.60407  ? 76  ALA   A C    1 
ATOM   1332 O  O    . ALA   A 1 76  ? 39.72154 4.24759   -14.17560 1.000 32.02277  ? 76  ALA   A O    1 
ATOM   1333 C  CB   . ALA   A 1 76  ? 38.80698 1.30217   -12.83510 1.000 30.95259  ? 76  ALA   A CB   1 
ATOM   1334 H  H    . ALA   A 1 76  ? 37.83888 2.44248   -10.92841 1.000 34.10554  ? 76  ALA   A H    1 
ATOM   1335 H  HA   . ALA   A 1 76  ? 40.06901 2.79384   -12.21000 1.000 36.11177  ? 76  ALA   A HA   1 
ATOM   1336 H  HB1  . ALA   A 1 76  ? 39.29506 1.10347   -13.64947 1.000 37.15738  ? 76  ALA   A HB1  1 
ATOM   1337 H  HB2  . ALA   A 1 76  ? 39.07941 0.69473   -12.12962 1.000 37.15738  ? 76  ALA   A HB2  1 
ATOM   1338 H  HB3  . ALA   A 1 76  ? 37.85339 1.21984   -12.99255 1.000 37.15738  ? 76  ALA   A HB3  1 
ATOM   1339 N  N    . GLU   A 1 77  ? 37.52684 4.01765   -13.75332 1.000 32.59148  ? 77  GLU   A N    1 
ATOM   1340 C  CA   A GLU   A 1 77  ? 37.16846 4.97892   -14.78524 0.510 32.44057  ? 77  GLU   A CA   1 
ATOM   1341 C  CA   B GLU   A 1 77  ? 37.16430 4.98112   -14.78236 0.490 32.43118  ? 77  GLU   A CA   1 
ATOM   1342 C  C    . GLU   A 1 77  ? 37.70900 6.36339   -14.44843 1.000 33.49978  ? 77  GLU   A C    1 
ATOM   1343 O  O    . GLU   A 1 77  ? 38.18742 7.07967   -15.32932 1.000 31.88897  ? 77  GLU   A O    1 
ATOM   1344 C  CB   A GLU   A 1 77  ? 35.64982 5.01675   -14.95802 0.510 39.04875  ? 77  GLU   A CB   1 
ATOM   1345 C  CB   B GLU   A 1 77  ? 35.64502 5.04729   -14.94599 0.490 38.93873  ? 77  GLU   A CB   1 
ATOM   1346 C  CG   A GLU   A 1 77  ? 35.03455 3.66898   -15.34392 0.510 33.47400  ? 77  GLU   A CG   1 
ATOM   1347 C  CG   B GLU   A 1 77  ? 35.18861 5.99088   -16.06137 0.490 40.10413  ? 77  GLU   A CG   1 
ATOM   1348 C  CD   A GLU   A 1 77  ? 33.52552 3.73731   -15.52420 0.510 57.91737  ? 77  GLU   A CD   1 
ATOM   1349 C  CD   B GLU   A 1 77  ? 33.72227 6.38013   -15.94809 0.490 58.97391  ? 77  GLU   A CD   1 
ATOM   1350 O  OE1  A GLU   A 1 77  ? 33.02103 4.78552   -15.98158 0.510 50.89768  ? 77  GLU   A OE1  1 
ATOM   1351 O  OE1  B GLU   A 1 77  ? 33.10284 6.09746   -14.89798 0.490 56.17537  ? 77  GLU   A OE1  1 
ATOM   1352 O  OE2  A GLU   A 1 77  ? 32.84205 2.74029   -15.20628 0.510 46.98900  ? 77  GLU   A OE2  1 
ATOM   1353 O  OE2  B GLU   A 1 77  ? 33.19014 6.97576   -16.91051 0.490 56.36585  ? 77  GLU   A OE2  1 
ATOM   1354 H  H    A GLU   A 1 77  ? 36.86032 3.67266   -13.33340 0.510 39.12405  ? 77  GLU   A H    1 
ATOM   1355 H  H    B GLU   A 1 77  ? 36.86089 3.67071   -13.33411 0.490 39.12405  ? 77  GLU   A H    1 
ATOM   1356 H  HA   A GLU   A 1 77  ? 37.55697 4.70070   -15.62937 0.510 38.94296  ? 77  GLU   A HA   1 
ATOM   1357 H  HA   B GLU   A 1 77  ? 37.54518 4.68756   -15.62478 0.490 38.93168  ? 77  GLU   A HA   1 
ATOM   1358 H  HB2  A GLU   A 1 77  ? 35.24829 5.29566   -14.12023 0.510 46.87278  ? 77  GLU   A HB2  1 
ATOM   1359 H  HB2  B GLU   A 1 77  ? 35.31444 4.15954   -15.15461 0.490 46.74075  ? 77  GLU   A HB2  1 
ATOM   1360 H  HB3  A GLU   A 1 77  ? 35.43212 5.65203   -15.65796 0.510 46.87278  ? 77  GLU   A HB3  1 
ATOM   1361 H  HB3  B GLU   A 1 77  ? 35.25473 5.35979   -14.11478 0.490 46.74075  ? 77  GLU   A HB3  1 
ATOM   1362 H  HG2  A GLU   A 1 77  ? 35.42308 3.37309   -16.18201 0.510 40.18308  ? 77  GLU   A HG2  1 
ATOM   1363 H  HG2  B GLU   A 1 77  ? 35.71730 6.80323   -16.02291 0.490 48.13923  ? 77  GLU   A HG2  1 
ATOM   1364 H  HG3  A GLU   A 1 77  ? 35.22359 3.02394   -14.64457 0.510 40.18308  ? 77  GLU   A HG3  1 
ATOM   1365 H  HG3  B GLU   A 1 77  ? 35.31615 5.55225   -16.91708 0.490 48.13923  ? 77  GLU   A HG3  1 
ATOM   1366 N  N    . LYS   A 1 78  ? 37.64619 6.75343   -13.17463 1.000 30.37428  ? 78  LYS   A N    1 
ATOM   1367 C  CA   . LYS   A 1 78  ? 38.10254 8.07710   -12.76686 1.000 32.56321  ? 78  LYS   A CA   1 
ATOM   1368 C  C    . LYS   A 1 78  ? 39.58093 8.26578   -13.05091 1.000 32.68007  ? 78  LYS   A C    1 
ATOM   1369 O  O    . LYS   A 1 78  ? 39.99149 9.28646   -13.61860 1.000 29.98470  ? 78  LYS   A O    1 
ATOM   1370 C  CB   . LYS   A 1 78  ? 37.81853 8.28382   -11.27469 1.000 33.63657  ? 78  LYS   A CB   1 
ATOM   1371 C  CG   . LYS   A 1 78  ? 38.34239 9.59025   -10.68455 1.000 35.54826  ? 78  LYS   A CG   1 
ATOM   1372 C  CD   . LYS   A 1 78  ? 38.14900 9.61183   -9.16850  1.000 34.60104  ? 78  LYS   A CD   1 
ATOM   1373 C  CE   . LYS   A 1 78  ? 38.70534 10.88974  -8.53851  1.000 45.10797  ? 78  LYS   A CE   1 
ATOM   1374 N  NZ   . LYS   A 1 78  ? 37.95333 12.10004  -8.97409  1.000 51.82498  ? 78  LYS   A NZ   1 
ATOM   1375 H  H    . LYS   A 1 78  ? 37.34417 6.27089   -12.53001 1.000 36.46341  ? 78  LYS   A H    1 
ATOM   1376 H  HA   . LYS   A 1 78  ? 37.61229 8.74369   -13.27305 1.000 39.09013  ? 78  LYS   A HA   1 
ATOM   1377 H  HB2  . LYS   A 1 78  ? 36.85776 8.27109   -11.14186 1.000 40.37815  ? 78  LYS   A HB2  1 
ATOM   1378 H  HB3  . LYS   A 1 78  ? 38.23127 7.55760   -10.78159 1.000 40.37815  ? 78  LYS   A HB3  1 
ATOM   1379 H  HG2  . LYS   A 1 78  ? 39.28940 9.67630   -10.87605 1.000 42.67218  ? 78  LYS   A HG2  1 
ATOM   1380 H  HG3  . LYS   A 1 78  ? 37.85712 10.33741  -11.06817 1.000 42.67218  ? 78  LYS   A HG3  1 
ATOM   1381 H  HD2  . LYS   A 1 78  ? 37.20154 9.56231   -8.96657  1.000 41.53551  ? 78  LYS   A HD2  1 
ATOM   1382 H  HD3  . LYS   A 1 78  ? 38.61174 8.85473   -8.77661  1.000 41.53551  ? 78  LYS   A HD3  1 
ATOM   1383 H  HE2  . LYS   A 1 78  ? 38.64044 10.82402  -7.57292  1.000 54.14384  ? 78  LYS   A HE2  1 
ATOM   1384 H  HE3  . LYS   A 1 78  ? 39.63253 10.99807  -8.80209  1.000 54.14384  ? 78  LYS   A HE3  1 
ATOM   1385 H  HZ1  . LYS   A 1 78  ? 38.28327 12.82361  -8.57448  1.000 62.20424  ? 78  LYS   A HZ1  1 
ATOM   1386 H  HZ2  . LYS   A 1 78  ? 38.02222 12.20028  -9.85574  1.000 62.20424  ? 78  LYS   A HZ2  1 
ATOM   1387 H  HZ3  . LYS   A 1 78  ? 37.09361 12.01801  -8.75902  1.000 62.20424  ? 78  LYS   A HZ3  1 
ATOM   1388 N  N    . TYR   A 1 79  ? 40.40267 7.29811   -12.65097 1.000 25.31729  ? 79  TYR   A N    1 
ATOM   1389 C  CA   . TYR   A 1 79  ? 41.84758 7.44593   -12.69335 1.000 27.25624  ? 79  TYR   A CA   1 
ATOM   1390 C  C    . TYR   A 1 79  ? 42.49631 6.81436   -13.91500 1.000 29.29620  ? 79  TYR   A C    1 
ATOM   1391 O  O    . TYR   A 1 79  ? 43.68282 7.07162   -14.15798 1.000 32.25364  ? 79  TYR   A O    1 
ATOM   1392 C  CB   . TYR   A 1 79  ? 42.47910 6.85413   -11.43203 1.000 29.43402  ? 79  TYR   A CB   1 
ATOM   1393 C  CG   . TYR   A 1 79  ? 42.18822 7.65255   -10.19066 1.000 29.71936  ? 79  TYR   A CG   1 
ATOM   1394 C  CD1  . TYR   A 1 79  ? 42.68823 8.92740   -10.04428 1.000 27.51802  ? 79  TYR   A CD1  1 
ATOM   1395 C  CD2  . TYR   A 1 79  ? 41.42068 7.12697   -9.17492  1.000 34.20055  ? 79  TYR   A CD2  1 
ATOM   1396 C  CE1  . TYR   A 1 79  ? 42.43121 9.68351   -8.91082  1.000 30.08811  ? 79  TYR   A CE1  1 
ATOM   1397 C  CE2  . TYR   A 1 79  ? 41.15995 7.85832   -8.03093  1.000 32.22642  ? 79  TYR   A CE2  1 
ATOM   1398 C  CZ   . TYR   A 1 79  ? 41.66586 9.13738   -7.91341  1.000 32.85104  ? 79  TYR   A CZ   1 
ATOM   1399 O  OH   . TYR   A 1 79  ? 41.40111 9.86294   -6.78989  1.000 35.67785  ? 79  TYR   A OH   1 
ATOM   1400 H  H    . TYR   A 1 79  ? 40.14002 6.53753   -12.34744 1.000 30.39502  ? 79  TYR   A H    1 
ATOM   1401 H  HA   . TYR   A 1 79  ? 42.04860 8.39459   -12.71659 1.000 32.72175  ? 79  TYR   A HA   1 
ATOM   1402 H  HB2  . TYR   A 1 79  ? 42.13226 5.95818   -11.29830 1.000 35.33509  ? 79  TYR   A HB2  1 
ATOM   1403 H  HB3  . TYR   A 1 79  ? 43.44166 6.82338   -11.54796 1.000 35.33509  ? 79  TYR   A HB3  1 
ATOM   1404 H  HD1  . TYR   A 1 79  ? 43.21118 9.29008   -10.72242 1.000 33.03590  ? 79  TYR   A HD1  1 
ATOM   1405 H  HD2  . TYR   A 1 79  ? 41.07310 6.26855   -9.25974  1.000 41.05493  ? 79  TYR   A HD2  1 
ATOM   1406 H  HE1  . TYR   A 1 79  ? 42.77170 10.54504  -8.82884  1.000 36.12001  ? 79  TYR   A HE1  1 
ATOM   1407 H  HE2  . TYR   A 1 79  ? 40.64812 7.49171   -7.34643  1.000 38.68598  ? 79  TYR   A HE2  1 
ATOM   1408 H  HH   . TYR   A 1 79  ? 41.76742 10.61707  -6.84194  1.000 42.82769  ? 79  TYR   A HH   1 
ATOM   1409 N  N    . GLY   A 1 80  ? 41.78018 5.97388   -14.64755 1.000 31.86946  ? 80  GLY   A N    1 
ATOM   1410 C  CA   . GLY   A 1 80  ? 42.25280 5.46383   -15.92385 1.000 30.56304  ? 80  GLY   A CA   1 
ATOM   1411 C  C    . GLY   A 1 80  ? 42.93126 4.10319   -15.89791 1.000 34.90871  ? 80  GLY   A C    1 
ATOM   1412 O  O    . GLY   A 1 80  ? 43.39577 3.64094   -16.95331 1.000 31.21657  ? 80  GLY   A O    1 
ATOM   1413 H  H    . GLY   A 1 80  ? 41.00410 5.67957   -14.42244 1.000 38.25762  ? 80  GLY   A H    1 
ATOM   1414 H  HA2  . GLY   A 1 80  ? 41.49444 5.39754   -16.52501 1.000 36.68992  ? 80  GLY   A HA2  1 
ATOM   1415 H  HA3  . GLY   A 1 80  ? 42.89006 6.09796   -16.28811 1.000 36.68992  ? 80  GLY   A HA3  1 
ATOM   1416 N  N    . PHE   A 1 81  ? 42.99675 3.43835   -14.75636 1.000 30.20308  ? 81  PHE   A N    1 
ATOM   1417 C  CA   . PHE   A 1 81  ? 43.59313 2.10957   -14.71120 1.000 34.26726  ? 81  PHE   A CA   1 
ATOM   1418 C  C    . PHE   A 1 81  ? 42.52672 1.06236   -15.03765 1.000 27.68490  ? 81  PHE   A C    1 
ATOM   1419 O  O    . PHE   A 1 81  ? 41.31898 1.31290   -14.93820 1.000 32.66104  ? 81  PHE   A O    1 
ATOM   1420 C  CB   . PHE   A 1 81  ? 44.26756 1.82155   -13.36524 1.000 32.09877  ? 81  PHE   A CB   1 
ATOM   1421 C  CG   . PHE   A 1 81  ? 43.36501 1.92780   -12.15870 1.000 28.45906  ? 81  PHE   A CG   1 
ATOM   1422 C  CD1  . PHE   A 1 81  ? 42.60131 0.84505   -11.74061 1.000 31.30316  ? 81  PHE   A CD1  1 
ATOM   1423 C  CD2  . PHE   A 1 81  ? 43.30785 3.10137   -11.41383 1.000 28.80322  ? 81  PHE   A CD2  1 
ATOM   1424 C  CE1  . PHE   A 1 81  ? 41.79246 0.92342   -10.62344 1.000 32.22296  ? 81  PHE   A CE1  1 
ATOM   1425 C  CE2  . PHE   A 1 81  ? 42.49125 3.18901   -10.29051 1.000 30.37465  ? 81  PHE   A CE2  1 
ATOM   1426 C  CZ   . PHE   A 1 81  ? 41.72820 2.10522   -9.90299  1.000 28.16623  ? 81  PHE   A CZ   1 
ATOM   1427 H  H    . PHE   A 1 81  ? 42.70656 3.73008   -14.00118 1.000 36.25797  ? 81  PHE   A H    1 
ATOM   1428 H  HA   . PHE   A 1 81  ? 44.29934 2.04995   -15.37348 1.000 41.13498  ? 81  PHE   A HA   1 
ATOM   1429 H  HB2  . PHE   A 1 81  ? 44.61898 0.91768   -13.38582 1.000 38.53279  ? 81  PHE   A HB2  1 
ATOM   1430 H  HB3  . PHE   A 1 81  ? 44.99098 2.45607   -13.24303 1.000 38.53279  ? 81  PHE   A HB3  1 
ATOM   1431 H  HD1  . PHE   A 1 81  ? 42.63535 0.05071   -12.22305 1.000 37.57806  ? 81  PHE   A HD1  1 
ATOM   1432 H  HD2  . PHE   A 1 81  ? 43.82028 3.83430   -11.66905 1.000 34.57814  ? 81  PHE   A HD2  1 
ATOM   1433 H  HE1  . PHE   A 1 81  ? 41.29305 0.18588   -10.35599 1.000 38.68182  ? 81  PHE   A HE1  1 
ATOM   1434 H  HE2  . PHE   A 1 81  ? 42.45932 3.97854   -9.80008  1.000 36.46385  ? 81  PHE   A HE2  1 
ATOM   1435 H  HZ   . PHE   A 1 81  ? 41.17239 2.16844   -9.16005  1.000 33.81374  ? 81  PHE   A HZ   1 
ATOM   1436 N  N    . LYS   A 1 82  ? 42.99118 -0.10852  -15.46562 1.000 33.57185  ? 82  LYS   A N    1 
ATOM   1437 C  CA   A LYS   A 1 82  ? 42.08584 -1.18415  -15.85211 0.700 35.67329  ? 82  LYS   A CA   1 
ATOM   1438 C  CA   B LYS   A 1 82  ? 42.09228 -1.18925  -15.85083 0.300 35.88122  ? 82  LYS   A CA   1 
ATOM   1439 C  C    . LYS   A 1 82  ? 41.38199 -1.74678  -14.62679 1.000 28.61516  ? 82  LYS   A C    1 
ATOM   1440 O  O    . LYS   A 1 82  ? 41.98203 -1.90560  -13.56896 1.000 28.26558  ? 82  LYS   A O    1 
ATOM   1441 C  CB   A LYS   A 1 82  ? 42.86628 -2.28461  -16.57986 0.700 44.62302  ? 82  LYS   A CB   1 
ATOM   1442 C  CB   B LYS   A 1 82  ? 42.87206 -2.30283  -16.55561 0.300 44.49086  ? 82  LYS   A CB   1 
ATOM   1443 C  CG   A LYS   A 1 82  ? 42.00051 -3.30316  -17.31070 0.700 52.35594  ? 82  LYS   A CG   1 
ATOM   1444 C  CG   B LYS   A 1 82  ? 42.08893 -3.60144  -16.75110 0.300 33.17852  ? 82  LYS   A CG   1 
ATOM   1445 C  CD   A LYS   A 1 82  ? 42.80408 -4.05946  -18.37069 0.700 50.52558  ? 82  LYS   A CD   1 
ATOM   1446 C  CD   B LYS   A 1 82  ? 42.85778 -4.58771  -17.62817 0.300 40.03059  ? 82  LYS   A CD   1 
ATOM   1447 C  CE   A LYS   A 1 82  ? 41.94957 -5.12199  -19.06642 0.700 62.19452  ? 82  LYS   A CE   1 
ATOM   1448 C  CE   B LYS   A 1 82  ? 42.05063 -5.85141  -17.92276 0.300 32.29755  ? 82  LYS   A CE   1 
ATOM   1449 N  NZ   A LYS   A 1 82  ? 42.61401 -5.67737  -20.29222 0.700 49.71901  ? 82  LYS   A NZ   1 
ATOM   1450 N  NZ   B LYS   A 1 82  ? 42.10874 -6.85607  -16.81241 0.300 36.73053  ? 82  LYS   A NZ   1 
ATOM   1451 H  H    A LYS   A 1 82  ? 43.82505 -0.30486  -15.54118 0.700 40.30050  ? 82  LYS   A H    1 
ATOM   1452 H  H    B LYS   A 1 82  ? 43.82548 -0.30264  -15.54218 0.300 40.30050  ? 82  LYS   A H    1 
ATOM   1453 H  HA   A LYS   A 1 82  ? 41.40712 -0.84651  -16.45729 0.700 42.82222  ? 82  LYS   A HA   1 
ATOM   1454 H  HA   B LYS   A 1 82  ? 41.42403 -0.85056  -16.46697 0.300 43.07173  ? 82  LYS   A HA   1 
ATOM   1455 H  HB2  A LYS   A 1 82  ? 43.44524 -1.86822  -17.23737 0.700 53.56190  ? 82  LYS   A HB2  1 
ATOM   1456 H  HB2  B LYS   A 1 82  ? 43.13738 -1.98608  -17.43320 0.300 53.40330  ? 82  LYS   A HB2  1 
ATOM   1457 H  HB3  A LYS   A 1 82  ? 43.39804 -2.76758  -15.92804 0.700 53.56190  ? 82  LYS   A HB3  1 
ATOM   1458 H  HB3  B LYS   A 1 82  ? 43.65791 -2.51172  -16.02673 0.300 53.40330  ? 82  LYS   A HB3  1 
ATOM   1459 H  HG2  A LYS   A 1 82  ? 41.65365 -3.94696  -16.67343 0.700 62.84140  ? 82  LYS   A HG2  1 
ATOM   1460 H  HG2  B LYS   A 1 82  ? 41.93359 -4.01664  -15.88832 0.300 39.82849  ? 82  LYS   A HG2  1 
ATOM   1461 H  HG3  A LYS   A 1 82  ? 41.26794 -2.84531  -17.75186 0.700 62.84140  ? 82  LYS   A HG3  1 
ATOM   1462 H  HG3  B LYS   A 1 82  ? 41.24237 -3.40505  -17.18200 0.300 39.82849  ? 82  LYS   A HG3  1 
ATOM   1463 H  HD2  A LYS   A 1 82  ? 43.11994 -3.43427  -19.04171 0.700 60.64496  ? 82  LYS   A HD2  1 
ATOM   1464 H  HD2  B LYS   A 1 82  ? 43.07163 -4.16251  -18.47337 0.300 48.05097  ? 82  LYS   A HD2  1 
ATOM   1465 H  HD3  A LYS   A 1 82  ? 43.55721 -4.50168  -17.94862 0.700 60.64496  ? 82  LYS   A HD3  1 
ATOM   1466 H  HD3  B LYS   A 1 82  ? 43.67324 -4.84991  -17.17301 0.300 48.05097  ? 82  LYS   A HD3  1 
ATOM   1467 H  HE2  A LYS   A 1 82  ? 41.79114 -5.85508  -18.45129 0.700 74.64770  ? 82  LYS   A HE2  1 
ATOM   1468 H  HE2  B LYS   A 1 82  ? 41.12130 -5.60787  -18.05673 0.300 38.77133  ? 82  LYS   A HE2  1 
ATOM   1469 H  HE3  A LYS   A 1 82  ? 41.10581 -4.72562  -19.33449 0.700 74.64770  ? 82  LYS   A HE3  1 
ATOM   1470 H  HE3  B LYS   A 1 82  ? 42.40246 -6.27073  -18.72356 0.300 38.77133  ? 82  LYS   A HE3  1 
ATOM   1471 H  HZ1  A LYS   A 1 82  ? 42.10132 -6.30629  -20.65788 0.700 59.67708  ? 82  LYS   A HZ1  1 
ATOM   1472 H  HZ1  B LYS   A 1 82  ? 41.61232 -7.56567  -17.01766 0.300 44.09091  ? 82  LYS   A HZ1  1 
ATOM   1473 H  HZ2  A LYS   A 1 82  ? 42.74484 -5.02903  -20.88775 0.700 59.67708  ? 82  LYS   A HZ2  1 
ATOM   1474 H  HZ2  B LYS   A 1 82  ? 42.94918 -7.11905  -16.68352 0.300 44.09091  ? 82  LYS   A HZ2  1 
ATOM   1475 H  HZ3  A LYS   A 1 82  ? 43.40017 -6.03470  -20.07689 0.700 59.67708  ? 82  LYS   A HZ3  1 
ATOM   1476 H  HZ3  B LYS   A 1 82  ? 41.80015 -6.49573  -16.05940 0.300 44.09091  ? 82  LYS   A HZ3  1 
ATOM   1477 N  N    . TYR   A 1 83  ? 40.10299 -2.02547  -14.77108 1.000 34.81639  ? 83  TYR   A N    1 
ATOM   1478 C  CA   . TYR   A 1 83  ? 39.35379 -2.59017  -13.66767 1.000 32.08444  ? 83  TYR   A CA   1 
ATOM   1479 C  C    . TYR   A 1 83  ? 39.96590 -3.93191  -13.29486 1.000 35.82198  ? 83  TYR   A C    1 
ATOM   1480 O  O    . TYR   A 1 83  ? 40.14948 -4.77911  -14.17473 1.000 32.52912  ? 83  TYR   A O    1 
ATOM   1481 C  CB   . TYR   A 1 83  ? 37.88075 -2.77476  -14.01225 1.000 36.75277  ? 83  TYR   A CB   1 
ATOM   1482 C  CG   . TYR   A 1 83  ? 37.10508 -3.43440  -12.88180 1.000 30.32090  ? 83  TYR   A CG   1 
ATOM   1483 C  CD1  . TYR   A 1 83  ? 36.77593 -2.72864  -11.73213 1.000 34.70183  ? 83  TYR   A CD1  1 
ATOM   1484 C  CD2  . TYR   A 1 83  ? 36.69228 -4.75902  -12.97516 1.000 41.50170  ? 83  TYR   A CD2  1 
ATOM   1485 C  CE1  . TYR   A 1 83  ? 36.07869 -3.32383  -10.70561 1.000 43.12791  ? 83  TYR   A CE1  1 
ATOM   1486 C  CE2  . TYR   A 1 83  ? 35.98515 -5.36208  -11.95410 1.000 45.53562  ? 83  TYR   A CE2  1 
ATOM   1487 C  CZ   . TYR   A 1 83  ? 35.68528 -4.64224  -10.82161 1.000 45.66617  ? 83  TYR   A CZ   1 
ATOM   1488 O  OH   . TYR   A 1 83  ? 34.98930 -5.23421  -9.79508  1.000 56.88117  ? 83  TYR   A OH   1 
ATOM   1489 H  H    . TYR   A 1 83  ? 39.64804 -1.89903  -15.48985 1.000 41.79394  ? 83  TYR   A H    1 
ATOM   1490 H  HA   . TYR   A 1 83  ? 39.39661 -1.98168  -12.91347 1.000 38.51560  ? 83  TYR   A HA   1 
ATOM   1491 H  HB2  . TYR   A 1 83  ? 37.48364 -1.90698  -14.18592 1.000 44.11760  ? 83  TYR   A HB2  1 
ATOM   1492 H  HB3  . TYR   A 1 83  ? 37.80629 -3.33715  -14.79906 1.000 44.11760  ? 83  TYR   A HB3  1 
ATOM   1493 H  HD1  . TYR   A 1 83  ? 37.03123 -1.83775  -11.65440 1.000 41.65647  ? 83  TYR   A HD1  1 
ATOM   1494 H  HD2  . TYR   A 1 83  ? 36.89631 -5.24780  -13.73960 1.000 49.81631  ? 83  TYR   A HD2  1 
ATOM   1495 H  HE1  . TYR   A 1 83  ? 35.87361 -2.84058  -9.93794  1.000 51.76777  ? 83  TYR   A HE1  1 
ATOM   1496 H  HE2  . TYR   A 1 83  ? 35.71379 -6.24822  -12.03170 1.000 54.65702  ? 83  TYR   A HE2  1 
ATOM   1497 H  HH   . TYR   A 1 83  ? 34.88277 -6.05207  -9.95433  1.000 68.27167  ? 83  TYR   A HH   1 
ATOM   1498 N  N    . PRO   A 1 84  ? 40.31674 -4.15355  -12.02901 1.000 31.31004  ? 84  PRO   A N    1 
ATOM   1499 C  CA   . PRO   A 1 84  ? 40.93720 -5.42871  -11.65184 1.000 32.46025  ? 84  PRO   A CA   1 
ATOM   1500 C  C    . PRO   A 1 84  ? 39.92176 -6.55997  -11.66655 1.000 36.59715  ? 84  PRO   A C    1 
ATOM   1501 O  O    . PRO   A 1 84  ? 38.82475 -6.43668  -11.12295 1.000 40.51554  ? 84  PRO   A O    1 
ATOM   1502 C  CB   . PRO   A 1 84  ? 41.45912 -5.16768  -10.23265 1.000 34.63581  ? 84  PRO   A CB   1 
ATOM   1503 C  CG   . PRO   A 1 84  ? 40.54615 -4.11152  -9.68640  1.000 32.41667  ? 84  PRO   A CG   1 
ATOM   1504 C  CD   . PRO   A 1 84  ? 40.18649 -3.24105  -10.87514 1.000 35.24507  ? 84  PRO   A CD   1 
ATOM   1505 H  HA   . PRO   A 1 84  ? 41.67462 -5.63875  -12.24597 1.000 38.96657  ? 84  PRO   A HA   1 
ATOM   1506 H  HB2  . PRO   A 1 84  ? 41.40811 -5.98010  -9.70514  1.000 41.57725  ? 84  PRO   A HB2  1 
ATOM   1507 H  HB3  . PRO   A 1 84  ? 42.37574 -4.85234  -10.26842 1.000 41.57725  ? 84  PRO   A HB3  1 
ATOM   1508 H  HG2  . PRO   A 1 84  ? 39.75412 -4.52416  -9.30785  1.000 38.91427  ? 84  PRO   A HG2  1 
ATOM   1509 H  HG3  . PRO   A 1 84  ? 41.00821 -3.59554  -9.00730  1.000 38.91427  ? 84  PRO   A HG3  1 
ATOM   1510 H  HD2  . PRO   A 1 84  ? 39.27715 -2.91239  -10.79782 1.000 42.30835  ? 84  PRO   A HD2  1 
ATOM   1511 H  HD3  . PRO   A 1 84  ? 40.80281 -2.49625  -10.95470 1.000 42.30835  ? 84  PRO   A HD3  1 
ATOM   1512 N  N    . GLU   A 1 85  ? 40.29906 -7.66868  -12.29012 1.000 31.24830  ? 85  GLU   A N    1 
ATOM   1513 C  CA   . GLU   A 1 85  ? 39.51285 -8.88815  -12.18335 1.000 28.67585  ? 85  GLU   A CA   1 
ATOM   1514 C  C    . GLU   A 1 85  ? 39.75875 -9.53298  -10.81690 1.000 27.53351  ? 85  GLU   A C    1 
ATOM   1515 O  O    . GLU   A 1 85  ? 40.83077 -9.39175  -10.22983 1.000 30.34047  ? 85  GLU   A O    1 
ATOM   1516 C  CB   . GLU   A 1 85  ? 39.88500 -9.86128  -13.29922 1.000 34.04667  ? 85  GLU   A CB   1 
ATOM   1517 C  CG   . GLU   A 1 85  ? 39.63466 -9.31540  -14.70334 1.000 33.64929  ? 85  GLU   A CG   1 
ATOM   1518 C  CD   . GLU   A 1 85  ? 40.07998 -10.27879 -15.80050 1.000 46.20784  ? 85  GLU   A CD   1 
ATOM   1519 O  OE1  . GLU   A 1 85  ? 40.47620 -11.41058 -15.49011 1.000 35.78946  ? 85  GLU   A OE1  1 
ATOM   1520 O  OE2  . GLU   A 1 85  ? 40.02955 -9.89116  -16.98208 1.000 56.96723  ? 85  GLU   A OE2  1 
ATOM   1521 H  H    . GLU   A 1 85  ? 41.00316 -7.73988  -12.77877 1.000 37.51223  ? 85  GLU   A H    1 
ATOM   1522 H  HA   . GLU   A 1 85  ? 38.56743 -8.68959  -12.27084 1.000 34.42529  ? 85  GLU   A HA   1 
ATOM   1523 H  HB2  . GLU   A 1 85  ? 40.82931 -10.07107 -13.22745 1.000 40.87027  ? 85  GLU   A HB2  1 
ATOM   1524 H  HB3  . GLU   A 1 85  ? 39.35710 -10.66865 -13.19729 1.000 40.87027  ? 85  GLU   A HB3  1 
ATOM   1525 H  HG2  . GLU   A 1 85  ? 38.68484 -9.15289  -14.81447 1.000 40.39342  ? 85  GLU   A HG2  1 
ATOM   1526 H  HG3  . GLU   A 1 85  ? 40.12796 -8.48743  -14.81305 1.000 40.39342  ? 85  GLU   A HG3  1 
ATOM   1527 N  N    . ASN   A 1 86  ? 38.74501 -10.24353 -10.32438 1.000 27.08015  ? 86  ASN   A N    1 
ATOM   1528 C  CA   . ASN   A 1 86  ? 38.86820 -11.02754 -9.08813  1.000 29.14719  ? 86  ASN   A CA   1 
ATOM   1529 C  C    . ASN   A 1 86  ? 39.21206 -10.14756 -7.89205  1.000 33.18480  ? 86  ASN   A C    1 
ATOM   1530 O  O    . ASN   A 1 86  ? 39.97161 -10.54439 -6.99926  1.000 29.29719  ? 86  ASN   A O    1 
ATOM   1531 C  CB   . ASN   A 1 86  ? 39.91411 -12.13186 -9.25460  1.000 33.34174  ? 86  ASN   A CB   1 
ATOM   1532 C  CG   . ASN   A 1 86  ? 39.58040 -13.07204 -10.39885 1.000 40.99843  ? 86  ASN   A CG   1 
ATOM   1533 O  OD1  . ASN   A 1 86  ? 40.33740 -13.18862 -11.36151 1.000 41.34780  ? 86  ASN   A OD1  1 
ATOM   1534 N  ND2  . ASN   A 1 86  ? 38.44232 -13.74429 -10.28904 1.000 36.54632  ? 86  ASN   A ND2  1 
ATOM   1535 H  H    . ASN   A 1 86  ? 37.96740 -10.29020 -10.68873 1.000 32.51046  ? 86  ASN   A H    1 
ATOM   1536 H  HA   . ASN   A 1 86  ? 38.00827 -11.43645 -8.90318  1.000 34.99090  ? 86  ASN   A HA   1 
ATOM   1537 H  HB2  . ASN   A 1 86  ? 40.77683 -11.72786 -9.43740  1.000 40.02436  ? 86  ASN   A HB2  1 
ATOM   1538 H  HB3  . ASN   A 1 86  ? 39.95844 -12.65361 -8.43808  1.000 40.02436  ? 86  ASN   A HB3  1 
ATOM   1539 H  HD21 . ASN   A 1 86  ? 38.20425 -14.29089 -10.90884 1.000 43.86985  ? 86  ASN   A HD21 1 
ATOM   1540 H  HD22 . ASN   A 1 86  ? 37.94245 -13.63357 -9.59804  1.000 43.86985  ? 86  ASN   A HD22 1 
ATOM   1541 N  N    . LEU   A 1 87  ? 38.62090 -8.95295  -7.84794  1.000 29.51254  ? 87  LEU   A N    1 
ATOM   1542 C  CA   . LEU   A 1 87  ? 38.89099 -8.05008  -6.73342  1.000 31.63331  ? 87  LEU   A CA   1 
ATOM   1543 C  C    . LEU   A 1 87  ? 38.55436 -8.69685  -5.39062  1.000 29.62866  ? 87  LEU   A C    1 
ATOM   1544 O  O    . LEU   A 1 87  ? 39.27750 -8.52106  -4.40166  1.000 28.01635  ? 87  LEU   A O    1 
ATOM   1545 C  CB   . LEU   A 1 87  ? 38.09814 -6.75628  -6.91819  1.000 30.64677  ? 87  LEU   A CB   1 
ATOM   1546 C  CG   . LEU   A 1 87  ? 38.25504 -5.73253  -5.79052  1.000 32.75178  ? 87  LEU   A CG   1 
ATOM   1547 C  CD1  . LEU   A 1 87  ? 39.69586 -5.27283  -5.64263  1.000 39.64499  ? 87  LEU   A CD1  1 
ATOM   1548 C  CD2  . LEU   A 1 87  ? 37.33702 -4.53817  -6.04244  1.000 45.21539  ? 87  LEU   A CD2  1 
ATOM   1549 H  H    . LEU   A 1 87  ? 38.07269 -8.64921  -8.43685  1.000 35.42932  ? 87  LEU   A H    1 
ATOM   1550 H  HA   . LEU   A 1 87  ? 39.83673 -7.83458  -6.72719  1.000 37.97424  ? 87  LEU   A HA   1 
ATOM   1551 H  HB2  . LEU   A 1 87  ? 38.39183 -6.33203  -7.73957  1.000 36.79040  ? 87  LEU   A HB2  1 
ATOM   1552 H  HB3  . LEU   A 1 87  ? 37.15637 -6.98050  -6.97896  1.000 36.79040  ? 87  LEU   A HB3  1 
ATOM   1553 H  HG   . LEU   A 1 87  ? 38.00393 -6.15423  -4.95386  1.000 39.31641  ? 87  LEU   A HG   1 
ATOM   1554 H  HD11 . LEU   A 1 87  ? 39.74055 -4.59022  -4.95492  1.000 47.58825  ? 87  LEU   A HD11 1 
ATOM   1555 H  HD12 . LEU   A 1 87  ? 40.24530 -6.03177  -5.39157  1.000 47.58825  ? 87  LEU   A HD12 1 
ATOM   1556 H  HD13 . LEU   A 1 87  ? 40.00003 -4.90990  -6.48919  1.000 47.58825  ? 87  LEU   A HD13 1 
ATOM   1557 H  HD21 . LEU   A 1 87  ? 37.61146 -3.80310  -5.47212  1.000 54.27274  ? 87  LEU   A HD21 1 
ATOM   1558 H  HD22 . LEU   A 1 87  ? 37.40631 -4.27760  -6.97421  1.000 54.27274  ? 87  LEU   A HD22 1 
ATOM   1559 H  HD23 . LEU   A 1 87  ? 36.42385 -4.79294  -5.83724  1.000 54.27274  ? 87  LEU   A HD23 1 
ATOM   1560 N  N    . ARG   A 1 88  ? 37.46302 -9.45639  -5.32427  1.000 32.62919  ? 88  ARG   A N    1 
ATOM   1561 C  CA   . ARG   A 1 88  ? 37.10179 -10.02851 -4.02602  1.000 36.75826  ? 88  ARG   A CA   1 
ATOM   1562 C  C    . ARG   A 1 88  ? 38.09695 -11.09443 -3.57963  1.000 26.95584  ? 88  ARG   A C    1 
ATOM   1563 O  O    . ARG   A 1 88  ? 38.28511 -11.29937 -2.37445  1.000 31.42266  ? 88  ARG   A O    1 
ATOM   1564 C  CB   . ARG   A 1 88  ? 35.67389 -10.57703 -4.06380  1.000 38.82379  ? 88  ARG   A CB   1 
ATOM   1565 C  CG   . ARG   A 1 88  ? 35.42589 -11.67922 -5.02483  1.000 37.36854  ? 88  ARG   A CG   1 
ATOM   1566 C  CD   . ARG   A 1 88  ? 33.91772 -12.01947 -5.09752  1.000 39.17916  ? 88  ARG   A CD   1 
ATOM   1567 N  NE   . ARG   A 1 88  ? 33.11622 -10.91560 -5.61029  1.000 37.05789  ? 88  ARG   A NE   1 
ATOM   1568 C  CZ   . ARG   A 1 88  ? 31.79414 -10.84659 -5.51874  1.000 34.50772  ? 88  ARG   A CZ   1 
ATOM   1569 N  NH1  . ARG   A 1 88  ? 31.08568 -11.81363 -4.95616  1.000 44.62262  ? 88  ARG   A NH1  1 
ATOM   1570 N  NH2  . ARG   A 1 88  ? 31.16574 -9.78178  -5.99815  1.000 44.34117  ? 88  ARG   A NH2  1 
ATOM   1571 H  H    . ARG   A 1 88  ? 36.94051 -9.64724  -5.98014  1.000 39.16930  ? 88  ARG   A H    1 
ATOM   1572 H  HA   . ARG   A 1 88  ? 37.11797 -9.32460  -3.35882  1.000 44.12419  ? 88  ARG   A HA   1 
ATOM   1573 H  HB2  . ARG   A 1 88  ? 35.45461 -10.91240 -3.18042  1.000 46.60282  ? 88  ARG   A HB2  1 
ATOM   1574 H  HB3  . ARG   A 1 88  ? 35.07635 -9.85056  -4.30061  1.000 46.60282  ? 88  ARG   A HB3  1 
ATOM   1575 H  HG2  . ARG   A 1 88  ? 35.72348 -11.41130 -5.90832  1.000 44.85652  ? 88  ARG   A HG2  1 
ATOM   1576 H  HG3  . ARG   A 1 88  ? 35.90641 -12.47192 -4.73911  1.000 44.85652  ? 88  ARG   A HG3  1 
ATOM   1577 H  HD2  . ARG   A 1 88  ? 33.79286 -12.77986 -5.68669  1.000 47.02927  ? 88  ARG   A HD2  1 
ATOM   1578 H  HD3  . ARG   A 1 88  ? 33.59834 -12.23377 -4.20704  1.000 47.02927  ? 88  ARG   A HD3  1 
ATOM   1579 H  HE   . ARG   A 1 88  ? 33.52677 -10.26663 -5.99744  1.000 44.48374  ? 88  ARG   A HE   1 
ATOM   1580 H  HH11 . ARG   A 1 88  ? 31.48165 -12.50804 -4.63899  1.000 53.56142  ? 88  ARG   A HH11 1 
ATOM   1581 H  HH12 . ARG   A 1 88  ? 30.22960 -11.74725 -4.90797  1.000 53.56142  ? 88  ARG   A HH12 1 
ATOM   1582 H  HH21 . ARG   A 1 88  ? 31.61476 -9.14573  -6.36342  1.000 53.22367  ? 88  ARG   A HH21 1 
ATOM   1583 H  HH22 . ARG   A 1 88  ? 30.30919 -9.72729  -5.94380  1.000 53.22367  ? 88  ARG   A HH22 1 
ATOM   1584 N  N    A GLU   A 1 89  ? 38.74849 -11.77465 -4.51826  0.530 27.77651  ? 89  GLU   A N    1 
ATOM   1585 N  N    B GLU   A 1 89  ? 38.76502 -11.75657 -4.51659  0.470 27.75567  ? 89  GLU   A N    1 
ATOM   1586 C  CA   A GLU   A 1 89  ? 39.80131 -12.71086 -4.14170  0.530 26.58357  ? 89  GLU   A CA   1 
ATOM   1587 C  CA   B GLU   A 1 89  ? 39.79903 -12.71540 -4.14606  0.470 26.59592  ? 89  GLU   A CA   1 
ATOM   1588 C  C    A GLU   A 1 89  ? 41.03449 -11.97072 -3.65251  0.530 32.04581  ? 89  GLU   A C    1 
ATOM   1589 C  C    B GLU   A 1 89  ? 41.07156 -12.01079 -3.69857  0.470 31.94186  ? 89  GLU   A C    1 
ATOM   1590 O  O    A GLU   A 1 89  ? 41.64546 -12.36253 -2.65370  0.530 30.08448  ? 89  GLU   A O    1 
ATOM   1591 O  O    B GLU   A 1 89  ? 41.74467 -12.47103 -2.77247  0.470 29.77961  ? 89  GLU   A O    1 
ATOM   1592 C  CB   A GLU   A 1 89  ? 40.15946 -13.62380 -5.31272  0.530 34.91409  ? 89  GLU   A CB   1 
ATOM   1593 C  CB   B GLU   A 1 89  ? 40.08357 -13.65972 -5.31295  0.470 35.22122  ? 89  GLU   A CB   1 
ATOM   1594 C  CG   A GLU   A 1 89  ? 39.43864 -14.96901 -5.29526  0.530 57.31201  ? 89  GLU   A CG   1 
ATOM   1595 C  CG   B GLU   A 1 89  ? 39.48998 -15.06166 -5.14686  0.470 57.82635  ? 89  GLU   A CG   1 
ATOM   1596 C  CD   A GLU   A 1 89  ? 39.88089 -15.85923 -4.14171  0.530 32.87611  ? 89  GLU   A CD   1 
ATOM   1597 C  CD   B GLU   A 1 89  ? 38.00218 -15.05583 -4.83628  0.470 38.60002  ? 89  GLU   A CD   1 
ATOM   1598 O  OE1  A GLU   A 1 89  ? 41.05929 -16.27945 -4.11207  0.530 40.17382  ? 89  GLU   A OE1  1 
ATOM   1599 O  OE1  B GLU   A 1 89  ? 37.18568 -14.84005 -5.75293  0.470 32.95536  ? 89  GLU   A OE1  1 
ATOM   1600 O  OE2  A GLU   A 1 89  ? 39.04941 -16.12352 -3.25193  0.530 50.40648  ? 89  GLU   A OE2  1 
ATOM   1601 O  OE2  B GLU   A 1 89  ? 37.64259 -15.26362 -3.66018  0.470 52.99799  ? 89  GLU   A OE2  1 
ATOM   1602 H  H    A GLU   A 1 89  ? 38.60352 -11.71404 -5.36379  0.530 33.34609  ? 89  GLU   A H    1 
ATOM   1603 H  H    B GLU   A 1 89  ? 38.64131 -11.67093 -5.36332  0.470 33.32107  ? 89  GLU   A H    1 
ATOM   1604 H  HA   A GLU   A 1 89  ? 39.47026 -13.27265 -3.42358  0.530 31.91455  ? 89  GLU   A HA   1 
ATOM   1605 H  HA   B GLU   A 1 89  ? 39.47954 -13.25369 -3.40507  0.470 31.92937  ? 89  GLU   A HA   1 
ATOM   1606 H  HB2  A GLU   A 1 89  ? 39.92541 -13.17446 -6.13989  0.530 41.91117  ? 89  GLU   A HB2  1 
ATOM   1607 H  HB2  B GLU   A 1 89  ? 39.70877 -13.27557 -6.12094  0.470 42.27973  ? 89  GLU   A HB2  1 
ATOM   1608 H  HB3  A GLU   A 1 89  ? 41.11306 -13.79982 -5.28912  0.530 41.91117  ? 89  GLU   A HB3  1 
ATOM   1609 H  HB3  B GLU   A 1 89  ? 41.04423 -13.75634 -5.40622  0.470 42.27973  ? 89  GLU   A HB3  1 
ATOM   1610 H  HG2  A GLU   A 1 89  ? 38.48493 -14.81548 -5.20710  0.530 68.78869  ? 89  GLU   A HG2  1 
ATOM   1611 H  HG2  B GLU   A 1 89  ? 39.61933 -15.55643 -5.97110  0.470 69.40589  ? 89  GLU   A HG2  1 
ATOM   1612 H  HG3  A GLU   A 1 89  ? 39.62400 -15.43774 -6.12401  0.530 68.78869  ? 89  GLU   A HG3  1 
ATOM   1613 H  HG3  B GLU   A 1 89  ? 39.94411 -15.50974 -4.41619  0.470 69.40589  ? 89  GLU   A HG3  1 
ATOM   1614 N  N    . ILE   A 1 90  ? 41.42080 -10.89935 -4.34386  1.000 27.07088  ? 90  ILE   A N    1 
ATOM   1615 C  CA   . ILE   A 1 90  ? 42.53877 -10.07967 -3.87192  1.000 29.56612  ? 90  ILE   A CA   1 
ATOM   1616 C  C    . ILE   A 1 90  ? 42.27933 -9.62515  -2.44418  1.000 27.45282  ? 90  ILE   A C    1 
ATOM   1617 O  O    . ILE   A 1 90  ? 43.15398 -9.68393  -1.57313  1.000 27.54657  ? 90  ILE   A O    1 
ATOM   1618 C  CB   . ILE   A 1 90  ? 42.74267 -8.86250  -4.79042  1.000 31.03972  ? 90  ILE   A CB   1 
ATOM   1619 C  CG1  . ILE   A 1 90  ? 43.15360 -9.29017  -6.20122  1.000 33.64417  ? 90  ILE   A CG1  1 
ATOM   1620 C  CG2  . ILE   A 1 90  ? 43.76845 -7.89491  -4.17725  1.000 36.08748  ? 90  ILE   A CG2  1 
ATOM   1621 C  CD1  . ILE   A 1 90  ? 43.12835 -8.14395  -7.20101  1.000 37.67556  ? 90  ILE   A CD1  1 
ATOM   1622 H  H    A ILE   A 1 90  ? 41.06009 -10.62879 -5.07617  0.530 32.49933  ? 90  ILE   A H    1 
ATOM   1623 H  H    B ILE   A 1 90  ? 41.03236 -10.59916 -5.04997  0.470 32.49933  ? 90  ILE   A H    1 
ATOM   1624 H  HA   . ILE   A 1 90  ? 43.34338 -10.62101 -3.89298  1.000 35.49362  ? 90  ILE   A HA   1 
ATOM   1625 H  HB   . ILE   A 1 90  ? 41.89382 -8.39944  -4.86746  1.000 37.26194  ? 90  ILE   A HB   1 
ATOM   1626 H  HG12 . ILE   A 1 90  ? 44.05687 -9.64258  -6.17276  1.000 40.38727  ? 90  ILE   A HG12 1 
ATOM   1627 H  HG13 . ILE   A 1 90  ? 42.54052 -9.97367  -6.51406  1.000 40.38727  ? 90  ILE   A HG13 1 
ATOM   1628 H  HG21 . ILE   A 1 90  ? 44.08800 -7.29388  -4.86830  1.000 43.31925  ? 90  ILE   A HG21 1 
ATOM   1629 H  HG22 . ILE   A 1 90  ? 43.34054 -7.38775  -3.46973  1.000 43.31925  ? 90  ILE   A HG22 1 
ATOM   1630 H  HG23 . ILE   A 1 90  ? 44.50884 -8.40693  -3.81592  1.000 43.31925  ? 90  ILE   A HG23 1 
ATOM   1631 H  HD11 . ILE   A 1 90  ? 43.17949 -8.50701  -8.09905  1.000 45.22494  ? 90  ILE   A HD11 1 
ATOM   1632 H  HD12 . ILE   A 1 90  ? 42.30225 -7.64749  -7.09148  1.000 45.22494  ? 90  ILE   A HD12 1 
ATOM   1633 H  HD13 . ILE   A 1 90  ? 43.88758 -7.56346  -7.03517  1.000 45.22494  ? 90  ILE   A HD13 1 
ATOM   1634 N  N    . SER   A 1 91  ? 41.06525 -9.14667  -2.18852  1.000 26.14285  ? 91  SER   A N    1 
ATOM   1635 C  CA   . SER   A 1 91  ? 40.75363 -8.57060  -0.88814  1.000 31.40172  ? 91  SER   A CA   1 
ATOM   1636 C  C    . SER   A 1 91  ? 40.78668 -9.62748  0.19873   1.000 29.42720  ? 91  SER   A C    1 
ATOM   1637 O  O    . SER   A 1 91  ? 41.29280 -9.37787  1.29411   1.000 30.59457  ? 91  SER   A O    1 
ATOM   1638 C  CB   . SER   A 1 91  ? 39.38248 -7.89084  -0.93969  1.000 39.56929  ? 91  SER   A CB   1 
ATOM   1639 O  OG   . SER   A 1 91  ? 39.39370 -6.83616  -1.88876  1.000 40.91696  ? 91  SER   A OG   1 
ATOM   1640 H  H    . SER   A 1 91  ? 40.41042 -9.14385  -2.74601  1.000 31.38569  ? 91  SER   A H    1 
ATOM   1641 H  HA   . SER   A 1 91  ? 41.41698 -7.89706  -0.67085  1.000 37.69633  ? 91  SER   A HA   1 
ATOM   1642 H  HB2  . SER   A 1 91  ? 38.71300 -8.54377  -1.19733  1.000 47.49742  ? 91  SER   A HB2  1 
ATOM   1643 H  HB3  . SER   A 1 91  ? 39.17345 -7.52907  -0.06429  1.000 47.49742  ? 91  SER   A HB3  1 
ATOM   1644 H  HG   . SER   A 1 91  ? 39.57284 -7.13823  -2.65183  1.000 49.11463  ? 91  SER   A HG   1 
ATOM   1645 N  N    . LEU   A 1 92  ? 40.23812 -10.80724 -0.06899  1.000 27.33526  ? 92  LEU   A N    1 
ATOM   1646 C  CA   . LEU   A 1 92  ? 40.25009 -11.84918 0.95749   1.000 34.35622  ? 92  LEU   A CA   1 
ATOM   1647 C  C    . LEU   A 1 92  ? 41.67238 -12.32001 1.24495   1.000 31.57910  ? 92  LEU   A C    1 
ATOM   1648 O  O    . LEU   A 1 92  ? 42.02931 -12.57735 2.39616   1.000 32.28473  ? 92  LEU   A O    1 
ATOM   1649 C  CB   . LEU   A 1 92  ? 39.37167 -13.01890 0.53134   1.000 41.12931  ? 92  LEU   A CB   1 
ATOM   1650 C  CG   . LEU   A 1 92  ? 39.12969 -14.08829 1.61123   1.000 41.66970  ? 92  LEU   A CG   1 
ATOM   1651 C  CD1  . LEU   A 1 92  ? 38.70904 -13.46950 2.94322   1.000 42.13965  ? 92  LEU   A CD1  1 
ATOM   1652 C  CD2  . LEU   A 1 92  ? 38.09047 -15.08805 1.15265   1.000 43.32931  ? 92  LEU   A CD2  1 
ATOM   1653 H  H    . LEU   A 1 92  ? 39.86390 -11.02614 -0.81172  1.000 32.81658  ? 92  LEU   A H    1 
ATOM   1654 H  HA   . LEU   A 1 92  ? 39.88101 -11.48504 1.77730   1.000 41.24174  ? 92  LEU   A HA   1 
ATOM   1655 H  HB2  . LEU   A 1 92  ? 38.50533 -12.67011 0.26923   1.000 49.36944  ? 92  LEU   A HB2  1 
ATOM   1656 H  HB3  . LEU   A 1 92  ? 39.79424 -13.45874 -0.22290  1.000 49.36944  ? 92  LEU   A HB3  1 
ATOM   1657 H  HG   . LEU   A 1 92  ? 39.96792 -14.55402 1.75737   1.000 50.01792  ? 92  LEU   A HG   1 
ATOM   1658 H  HD11 . LEU   A 1 92  ? 38.41730 -14.17534 3.54121   1.000 50.58185  ? 92  LEU   A HD11 1 
ATOM   1659 H  HD12 . LEU   A 1 92  ? 39.46717 -13.00241 3.32787   1.000 50.58185  ? 92  LEU   A HD12 1 
ATOM   1660 H  HD13 . LEU   A 1 92  ? 37.98178 -12.84704 2.78660   1.000 50.58185  ? 92  LEU   A HD13 1 
ATOM   1661 H  HD21 . LEU   A 1 92  ? 37.97887 -15.76469 1.83866   1.000 52.00944  ? 92  LEU   A HD21 1 
ATOM   1662 H  HD22 . LEU   A 1 92  ? 37.25085 -14.62540 1.00468   1.000 52.00944  ? 92  LEU   A HD22 1 
ATOM   1663 H  HD23 . LEU   A 1 92  ? 38.39104 -15.50000 0.32751   1.000 52.00944  ? 92  LEU   A HD23 1 
ATOM   1664 N  N    . ARG   A 1 93  ? 42.49881 -12.43775 0.21241   1.000 30.00734  ? 93  ARG   A N    1 
ATOM   1665 C  CA   . ARG   A 1 93  ? 43.88868 -12.82417 0.42627   1.000 26.21165  ? 93  ARG   A CA   1 
ATOM   1666 C  C    . ARG   A 1 93  ? 44.62920 -11.79143 1.25708   1.000 32.80276  ? 93  ARG   A C    1 
ATOM   1667 O  O    . ARG   A 1 93  ? 45.37227 -12.15238 2.16596   1.000 32.70307  ? 93  ARG   A O    1 
ATOM   1668 C  CB   . ARG   A 1 93  ? 44.60056 -13.01959 -0.92162  1.000 31.01025  ? 93  ARG   A CB   1 
ATOM   1669 C  CG   . ARG   A 1 93  ? 44.17223 -14.25915 -1.68505  1.000 37.74719  ? 93  ARG   A CG   1 
ATOM   1670 C  CD   . ARG   A 1 93  ? 44.51322 -14.13605 -3.17811  1.000 62.16680  ? 93  ARG   A CD   1 
ATOM   1671 N  NE   . ARG   A 1 93  ? 43.95490 -15.23458 -3.96374  1.000 46.42600  ? 93  ARG   A NE   1 
ATOM   1672 C  CZ   . ARG   A 1 93  ? 43.77935 -15.20455 -5.27964  1.000 73.34082  ? 93  ARG   A CZ   1 
ATOM   1673 N  NH1  . ARG   A 1 93  ? 44.10645 -14.14153 -5.99820  1.000 39.88432  ? 93  ARG   A NH1  1 
ATOM   1674 N  NH2  . ARG   A 1 93  ? 43.25411 -16.26327 -5.89053  1.000 52.40317  ? 93  ARG   A NH2  1 
ATOM   1675 H  H    . ARG   A 1 93  ? 42.28487 -12.30205 -0.60942  1.000 36.02308  ? 93  ARG   A H    1 
ATOM   1676 H  HA   . ARG   A 1 93  ? 43.90013 -13.66818 0.90418   1.000 31.46825  ? 93  ARG   A HA   1 
ATOM   1677 H  HB2  . ARG   A 1 93  ? 44.41512 -12.25081 -1.48331  1.000 37.22657  ? 93  ARG   A HB2  1 
ATOM   1678 H  HB3  . ARG   A 1 93  ? 45.55439 -13.08999 -0.75995  1.000 37.22657  ? 93  ARG   A HB3  1 
ATOM   1679 H  HG2  . ARG   A 1 93  ? 44.63443 -15.03367 -1.32812  1.000 45.31090  ? 93  ARG   A HG2  1 
ATOM   1680 H  HG3  . ARG   A 1 93  ? 43.21320 -14.37607 -1.59849  1.000 45.31090  ? 93  ARG   A HG3  1 
ATOM   1681 H  HD2  . ARG   A 1 93  ? 44.14964 -13.30444 -3.52035  1.000 74.61443  ? 93  ARG   A HD2  1 
ATOM   1682 H  HD3  . ARG   A 1 93  ? 45.47708 -14.14627 -3.28660  1.000 74.61443  ? 93  ARG   A HD3  1 
ATOM   1683 H  HE   . ARG   A 1 93  ? 43.72421 -15.94953 -3.54512  1.000 55.72547  ? 93  ARG   A HE   1 
ATOM   1684 H  HH11 . ARG   A 1 93  ? 44.44118 -13.44895 -5.61363  1.000 47.87546  ? 93  ARG   A HH11 1 
ATOM   1685 H  HH12 . ARG   A 1 93  ? 43.98416 -14.14369 -6.84946  1.000 47.87546  ? 93  ARG   A HH12 1 
ATOM   1686 H  HH21 . ARG   A 1 93  ? 43.03229 -16.95723 -5.43356  1.000 62.89807  ? 93  ARG   A HH21 1 
ATOM   1687 H  HH22 . ARG   A 1 93  ? 43.13639 -16.25369 -6.74238  1.000 62.89807  ? 93  ARG   A HH22 1 
ATOM   1688 N  N    . MET   A 1 94  ? 44.45638 -10.49586 0.95334   1.000 31.42569  ? 94  MET   A N    1 
ATOM   1689 C  CA   . MET   A 1 94  ? 45.15335 -9.47230  1.72482   1.000 28.38000  ? 94  MET   A CA   1 
ATOM   1690 C  C    . MET   A 1 94  ? 44.64021 -9.42542  3.17323   1.000 25.64174  ? 94  MET   A C    1 
ATOM   1691 O  O    . MET   A 1 94  ? 45.42127 -9.21479  4.10134   1.000 28.79680  ? 94  MET   A O    1 
ATOM   1692 C  CB   . MET   A 1 94  ? 44.99003 -8.09870  1.06870   1.000 25.37830  ? 94  MET   A CB   1 
ATOM   1693 C  CG   . MET   A 1 94  ? 45.77344 -7.90025  -0.22104  1.000 27.56052  ? 94  MET   A CG   1 
ATOM   1694 S  SD   . MET   A 1 94  ? 47.45952 -8.44618  -0.13773  1.000 34.99671  ? 94  MET   A SD   1 
ATOM   1695 C  CE   . MET   A 1 94  ? 48.08036 -8.16375  -1.76899  1.000 51.86284  ? 94  MET   A CE   1 
ATOM   1696 H  H    . MET   A 1 94  ? 43.95425 -10.19706 0.32232   1.000 37.72510  ? 94  MET   A H    1 
ATOM   1697 H  HA   . MET   A 1 94  ? 46.09867 -9.68970  1.72517   1.000 34.07028  ? 94  MET   A HA   1 
ATOM   1698 H  HB2  . MET   A 1 94  ? 44.05155 -7.96802  0.86113   1.000 30.46823  ? 94  MET   A HB2  1 
ATOM   1699 H  HB3  . MET   A 1 94  ? 45.28834 -7.42200  1.69639   1.000 30.46823  ? 94  MET   A HB3  1 
ATOM   1700 H  HG2  . MET   A 1 94  ? 45.33744 -8.39942  -0.92930  1.000 33.08690  ? 94  MET   A HG2  1 
ATOM   1701 H  HG3  . MET   A 1 94  ? 45.78091 -6.95477  -0.43764  1.000 33.08690  ? 94  MET   A HG3  1 
ATOM   1702 H  HE1  . MET   A 1 94  ? 48.96815 -8.54805  -1.83994  1.000 62.24968  ? 94  MET   A HE1  1 
ATOM   1703 H  HE2  . MET   A 1 94  ? 47.48591 -8.58369  -2.41023  1.000 62.24968  ? 94  MET   A HE2  1 
ATOM   1704 H  HE3  . MET   A 1 94  ? 48.11966 -7.20816  -1.93087  1.000 62.24968  ? 94  MET   A HE3  1 
ATOM   1705 N  N    . ALA   A 1 95  ? 43.32745 -9.59413  3.37644   1.000 30.80650  ? 95  ALA   A N    1 
ATOM   1706 C  CA   . ALA   A 1 95  ? 42.78518 -9.59718  4.74367   1.000 28.27224  ? 95  ALA   A CA   1 
ATOM   1707 C  C    . ALA   A 1 95  ? 43.37074 -10.73275 5.56227   1.000 32.08163  ? 95  ALA   A C    1 
ATOM   1708 O  O    . ALA   A 1 95  ? 43.80334 -10.53924 6.70679   1.000 33.51367  ? 95  ALA   A O    1 
ATOM   1709 C  CB   . ALA   A 1 95  ? 41.25979 -9.70052  4.71447   1.000 31.90766  ? 95  ALA   A CB   1 
ATOM   1710 H  H    . ALA   A 1 95  ? 42.74229 -9.70624  2.75626   1.000 36.98207  ? 95  ALA   A H    1 
ATOM   1711 H  HA   . ALA   A 1 95  ? 43.02288 -8.75719  5.16654   1.000 33.94096  ? 95  ALA   A HA   1 
ATOM   1712 H  HB1  . ALA   A 1 95  ? 40.92631 -9.70833  5.62531   1.000 38.30346  ? 95  ALA   A HB1  1 
ATOM   1713 H  HB2  . ALA   A 1 95  ? 40.90057 -8.93625  4.23724   1.000 38.30346  ? 95  ALA   A HB2  1 
ATOM   1714 H  HB3  . ALA   A 1 95  ? 41.00744 -10.52100 4.26278   1.000 38.30346  ? 95  ALA   A HB3  1 
ATOM   1715 N  N    . CYS   A 1 96  ? 43.37850 -11.93589 5.00056   1.000 33.67356  ? 96  CYS   A N    1 
ATOM   1716 C  CA   . CYS   A 1 96  ? 43.92922 -13.07442 5.72384   1.000 40.17698  ? 96  CYS   A CA   1 
ATOM   1717 C  C    . CYS   A 1 96  ? 45.41642 -12.89547 5.99205   1.000 40.48085  ? 96  CYS   A C    1 
ATOM   1718 O  O    . CYS   A 1 96  ? 45.90864 -13.31415 7.04491   1.000 38.08764  ? 96  CYS   A O    1 
ATOM   1719 C  CB   . CYS   A 1 96  ? 43.65897 -14.35935 4.94501   1.000 36.96693  ? 96  CYS   A CB   1 
ATOM   1720 S  SG   . CYS   A 1 96  ? 41.88696 -14.77768 4.81312   1.000 42.05248  ? 96  CYS   A SG   1 
ATOM   1721 H  H    . CYS   A 1 96  ? 43.07666 -12.11750 4.21601   1.000 40.42254  ? 96  CYS   A H    1 
ATOM   1722 H  HA   . CYS   A 1 96  ? 43.48741 -13.15473 6.58364   1.000 48.22665  ? 96  CYS   A HA   1 
ATOM   1723 H  HB2  . CYS   A 1 96  ? 44.00756 -14.25816 4.04548   1.000 44.37459  ? 96  CYS   A HB2  1 
ATOM   1724 H  HB3  . CYS   A 1 96  ? 44.10490 -15.09526 5.39278   1.000 44.37459  ? 96  CYS   A HB3  1 
ATOM   1725 H  HG   . CYS   A 1 96  ? 41.29754 -13.84010 4.35102   1.000 50.47724  ? 96  CYS   A HG   1 
ATOM   1726 N  N    . ARG   A 1 97  ? 46.13641 -12.24196 5.08230   1.000 39.09502  ? 97  ARG   A N    1 
ATOM   1727 C  CA   . ARG   A 1 97  ? 47.58143 -12.10818 5.21998   1.000 33.09713  ? 97  ARG   A CA   1 
ATOM   1728 C  C    . ARG   A 1 97  ? 47.98140 -11.03533 6.22764   1.000 38.46530  ? 97  ARG   A C    1 
ATOM   1729 O  O    . ARG   A 1 97  ? 48.88871 -11.25614 7.03636   1.000 38.57581  ? 97  ARG   A O    1 
ATOM   1730 C  CB   . ARG   A 1 97  ? 48.19799 -11.80945 3.84636   1.000 43.41860  ? 97  ARG   A CB   1 
ATOM   1731 C  CG   . ARG   A 1 97  ? 49.67960 -11.45759 3.87512   1.000 44.10067  ? 97  ARG   A CG   1 
ATOM   1732 C  CD   . ARG   A 1 97  ? 50.44557 -12.15993 2.74187   1.000 80.40699  ? 97  ARG   A CD   1 
ATOM   1733 N  NE   . ARG   A 1 97  ? 49.67983 -12.22625 1.50019   1.000 106.02354 ? 97  ARG   A NE   1 
ATOM   1734 C  CZ   . ARG   A 1 97  ? 49.79077 -13.19589 0.59943   1.000 129.57886 ? 97  ARG   A CZ   1 
ATOM   1735 N  NH1  . ARG   A 1 97  ? 50.62475 -14.21040 0.77499   1.000 85.37860  ? 97  ARG   A NH1  1 
ATOM   1736 N  NH2  . ARG   A 1 97  ? 49.04002 -13.15060 -0.50162  1.000 88.51474  ? 97  ARG   A NH2  1 
ATOM   1737 H  H    . ARG   A 1 97  ? 45.81259 -11.86836 4.37862   1.000 46.92830  ? 97  ARG   A H    1 
ATOM   1738 H  HA   . ARG   A 1 97  ? 47.93684 -12.94901 5.54797   1.000 39.73083  ? 97  ARG   A HA   1 
ATOM   1739 H  HB2  . ARG   A 1 97  ? 48.09520 -12.59415 3.28549   1.000 52.11660  ? 97  ARG   A HB2  1 
ATOM   1740 H  HB3  . ARG   A 1 97  ? 47.72699 -11.05750 3.45440   1.000 52.11660  ? 97  ARG   A HB3  1 
ATOM   1741 H  HG2  . ARG   A 1 97  ? 49.78479 -10.49945 3.76650   1.000 52.93507  ? 97  ARG   A HG2  1 
ATOM   1742 H  HG3  . ARG   A 1 97  ? 50.06071 -11.73936 4.72144   1.000 52.93507  ? 97  ARG   A HG3  1 
ATOM   1743 H  HD2  . ARG   A 1 97  ? 51.26452 -11.67167 2.56347   1.000 96.50266  ? 97  ARG   A HD2  1 
ATOM   1744 H  HD3  . ARG   A 1 97  ? 50.65306 -13.06723 3.01509   1.000 96.50266  ? 97  ARG   A HD3  1 
ATOM   1745 H  HE   . ARG   A 1 97  ? 49.11866 -11.59421 1.34136   1.000 127.24252 ? 97  ARG   A HE   1 
ATOM   1746 H  HH11 . ARG   A 1 97  ? 51.10917 -14.25101 1.48442   1.000 102.46859 ? 97  ARG   A HH11 1 
ATOM   1747 H  HH12 . ARG   A 1 97  ? 50.68164 -14.82828 0.17952   1.000 102.46859 ? 97  ARG   A HH12 1 
ATOM   1748 H  HH21 . ARG   A 1 97  ? 48.49205 -12.49878 -0.62192  1.000 106.23195 ? 97  ARG   A HH21 1 
ATOM   1749 H  HH22 . ARG   A 1 97  ? 49.10377 -13.77320 -1.09146  1.000 106.23195 ? 97  ARG   A HH22 1 
ATOM   1750 N  N    . TYR   A 1 98  ? 47.33409 -9.87234  6.20268   1.000 31.50045  ? 98  TYR   A N    1 
ATOM   1751 C  CA   . TYR   A 1 98  ? 47.75324 -8.73936  7.00388   1.000 39.45039  ? 98  TYR   A CA   1 
ATOM   1752 C  C    . TYR   A 1 98  ? 46.76552 -8.34915  8.08886   1.000 32.15191  ? 98  TYR   A C    1 
ATOM   1753 O  O    . TYR   A 1 98  ? 47.06138 -7.44540  8.86501   1.000 39.15287  ? 98  TYR   A O    1 
ATOM   1754 C  CB   . TYR   A 1 98  ? 47.99252 -7.51880  6.08924   1.000 35.74250  ? 98  TYR   A CB   1 
ATOM   1755 C  CG   . TYR   A 1 98  ? 49.06311 -7.75334  5.05487   1.000 34.72535  ? 98  TYR   A CG   1 
ATOM   1756 C  CD1  . TYR   A 1 98  ? 50.38506 -7.94516  5.43102   1.000 40.25379  ? 98  TYR   A CD1  1 
ATOM   1757 C  CD2  . TYR   A 1 98  ? 48.75590 -7.77443  3.69924   1.000 45.22339  ? 98  TYR   A CD2  1 
ATOM   1758 C  CE1  . TYR   A 1 98  ? 51.37110 -8.15889  4.49168   1.000 49.45031  ? 98  TYR   A CE1  1 
ATOM   1759 C  CE2  . TYR   A 1 98  ? 49.73973 -7.98327  2.75285   1.000 48.93582  ? 98  TYR   A CE2  1 
ATOM   1760 C  CZ   . TYR   A 1 98  ? 51.04294 -8.17249  3.15421   1.000 44.97758  ? 98  TYR   A CZ   1 
ATOM   1761 O  OH   . TYR   A 1 98  ? 52.03188 -8.38709  2.22112   1.000 50.88226  ? 98  TYR   A OH   1 
ATOM   1762 H  H    . TYR   A 1 98  ? 46.63903 -9.71808  5.72030   1.000 37.81481  ? 98  TYR   A H    1 
ATOM   1763 H  HA   . TYR   A 1 98  ? 48.58707 -8.96824  7.44347   1.000 47.35474  ? 98  TYR   A HA   1 
ATOM   1764 H  HB2  . TYR   A 1 98  ? 47.16803 -7.30910  5.62325   1.000 42.90528  ? 98  TYR   A HB2  1 
ATOM   1765 H  HB3  . TYR   A 1 98  ? 48.26549 -6.76542  6.63587   1.000 42.90528  ? 98  TYR   A HB3  1 
ATOM   1766 H  HD1  . TYR   A 1 98  ? 50.60986 -7.92922  6.33330   1.000 48.31882  ? 98  TYR   A HD1  1 
ATOM   1767 H  HD2  . TYR   A 1 98  ? 47.87623 -7.64620  3.42605   1.000 54.28234  ? 98  TYR   A HD2  1 
ATOM   1768 H  HE1  . TYR   A 1 98  ? 52.25164 -8.29294  4.75922   1.000 59.35465  ? 98  TYR   A HE1  1 
ATOM   1769 H  HE2  . TYR   A 1 98  ? 49.52289 -7.99603  1.84858   1.000 58.73726  ? 98  TYR   A HE2  1 
ATOM   1770 H  HH   . TYR   A 1 98  ? 51.70202 -8.39107  1.44861   1.000 61.07299  ? 98  TYR   A HH   1 
ATOM   1771 N  N    . GLY   A 1 99  ? 45.60307 -8.99259  8.15304   1.000 33.44812  ? 99  GLY   A N    1 
ATOM   1772 C  CA   . GLY   A 1 99  ? 44.65925 -8.69289  9.20690   1.000 34.71109  ? 99  GLY   A CA   1 
ATOM   1773 C  C    . GLY   A 1 99  ? 45.26619 -8.96262  10.57122  1.000 28.09883  ? 99  GLY   A C    1 
ATOM   1774 O  O    . GLY   A 1 99  ? 46.04054 -9.90807  10.75679  1.000 35.00283  ? 99  GLY   A O    1 
ATOM   1775 H  H    . GLY   A 1 99  ? 45.34407 -9.59992  7.60198   1.000 40.15202  ? 99  GLY   A H    1 
ATOM   1776 H  HA2  . GLY   A 1 99  ? 44.40195 -7.75884  9.15956   1.000 41.66758  ? 99  GLY   A HA2  1 
ATOM   1777 H  HA3  . GLY   A 1 99  ? 43.86780 -9.24410  9.10356   1.000 41.66758  ? 99  GLY   A HA3  1 
ATOM   1778 N  N    . GLU   A 1 100 ? 44.91629 -8.11541  11.52881  1.000 30.20178  ? 100 GLU   A N    1 
ATOM   1779 C  CA   . GLU   A 1 100 ? 45.51902 -8.18413  12.86005  1.000 33.03758  ? 100 GLU   A CA   1 
ATOM   1780 C  C    . GLU   A 1 100 ? 44.51129 -7.75410  13.90635  1.000 30.38989  ? 100 GLU   A C    1 
ATOM   1781 O  O    . GLU   A 1 100 ? 43.81914 -6.74813  13.73345  1.000 36.16667  ? 100 GLU   A O    1 
ATOM   1782 C  CB   . GLU   A 1 100 ? 46.76711 -7.28823  12.92245  1.000 41.03520  ? 100 GLU   A CB   1 
ATOM   1783 C  CG   . GLU   A 1 100 ? 47.56956 -7.36693  14.19627  1.000 60.51891  ? 100 GLU   A CG   1 
ATOM   1784 C  CD   . GLU   A 1 100 ? 48.74498 -6.39692  14.18961  1.000 77.32955  ? 100 GLU   A CD   1 
ATOM   1785 O  OE1  . GLU   A 1 100 ? 48.51343 -5.17318  14.01673  1.000 54.09022  ? 100 GLU   A OE1  1 
ATOM   1786 O  OE2  . GLU   A 1 100 ? 49.89669 -6.85803  14.34264  1.000 71.59983  ? 100 GLU   A OE2  1 
ATOM   1787 H  H    . GLU   A 1 100 ? 44.33265 -7.49058  11.43633  1.000 36.25641  ? 100 GLU   A H    1 
ATOM   1788 H  HA   . GLU   A 1 100 ? 45.76811 -9.09963  13.06186  1.000 39.65937  ? 100 GLU   A HA   1 
ATOM   1789 H  HB2  . GLU   A 1 100 ? 47.35770 -7.53914  12.19503  1.000 49.25651  ? 100 GLU   A HB2  1 
ATOM   1790 H  HB3  . GLU   A 1 100 ? 46.48464 -6.36623  12.81748  1.000 49.25651  ? 100 GLU   A HB3  1 
ATOM   1791 H  HG2  . GLU   A 1 100 ? 46.99781 -7.14560  14.94794  1.000 72.63697  ? 100 GLU   A HG2  1 
ATOM   1792 H  HG3  . GLU   A 1 100 ? 47.91879 -8.26608  14.29853  1.000 72.63697  ? 100 GLU   A HG3  1 
ATOM   1793 N  N    . LEU   A 1 101 ? 44.45223 -8.51605  15.00110  1.000 37.04705  ? 101 LEU   A N    1 
ATOM   1794 C  CA   . LEU   A 1 101 ? 43.55646 -8.22141  16.11010  1.000 41.62283  ? 101 LEU   A CA   1 
ATOM   1795 C  C    . LEU   A 1 101 ? 44.22794 -7.30608  17.13340  1.000 30.43352  ? 101 LEU   A C    1 
ATOM   1796 O  O    . LEU   A 1 101 ? 45.44957 -7.32705  17.29820  1.000 37.01515  ? 101 LEU   A O    1 
ATOM   1797 C  CB   . LEU   A 1 101 ? 43.13827 -9.51501  16.81938  1.000 41.94716  ? 101 LEU   A CB   1 
ATOM   1798 C  CG   . LEU   A 1 101 ? 42.34983 -10.56688 16.05001  1.000 37.91060  ? 101 LEU   A CG   1 
ATOM   1799 C  CD1  . LEU   A 1 101 ? 42.34554 -11.87795 16.82880  1.000 43.25767  ? 101 LEU   A CD1  1 
ATOM   1800 C  CD2  . LEU   A 1 101 ? 40.93445 -10.08302 15.80057  1.000 42.93158  ? 101 LEU   A CD2  1 
ATOM   1801 H  H    . LEU   A 1 101 ? 44.93093 -9.22003  15.12299  1.000 44.47073  ? 101 LEU   A H    1 
ATOM   1802 H  HA   . LEU   A 1 101 ? 42.76999 -7.77396  15.76059  1.000 49.96166  ? 101 LEU   A HA   1 
ATOM   1803 H  HB2  . LEU   A 1 101 ? 43.94842 -9.95164  17.12582  1.000 50.35087  ? 101 LEU   A HB2  1 
ATOM   1804 H  HB3  . LEU   A 1 101 ? 42.58918 -9.26397  17.57858  1.000 50.35087  ? 101 LEU   A HB3  1 
ATOM   1805 H  HG   . LEU   A 1 101 ? 42.76573 -10.72483 15.18805  1.000 45.50699  ? 101 LEU   A HG   1 
ATOM   1806 H  HD11 . LEU   A 1 101 ? 41.84174 -12.53994 16.32996  1.000 51.92348  ? 101 LEU   A HD11 1 
ATOM   1807 H  HD12 . LEU   A 1 101 ? 43.26033 -12.17825 16.94665  1.000 51.92348  ? 101 LEU   A HD12 1 
ATOM   1808 H  HD13 . LEU   A 1 101 ? 41.93190 -11.73018 17.69365  1.000 51.92348  ? 101 LEU   A HD13 1 
ATOM   1809 H  HD21 . LEU   A 1 101 ? 40.44409 -10.77235 15.32593  1.000 51.53217  ? 101 LEU   A HD21 1 
ATOM   1810 H  HD22 . LEU   A 1 101 ? 40.50815 -9.90101  16.65264  1.000 51.53217  ? 101 LEU   A HD22 1 
ATOM   1811 H  HD23 . LEU   A 1 101 ? 40.96685 -9.27342  15.26728  1.000 51.53217  ? 101 LEU   A HD23 1 
ATOM   1812 N  N    . TYR   A 1 102 ? 43.41545 -6.50630  17.82441  1.000 41.26716  ? 102 TYR   A N    1 
ATOM   1813 C  CA   . TYR   A 1 102 ? 43.90850 -5.82444  19.02199  1.000 38.46073  ? 102 TYR   A CA   1 
ATOM   1814 C  C    . TYR   A 1 102 ? 44.46910 -6.87395  19.98268  1.000 32.67323  ? 102 TYR   A C    1 
ATOM   1815 O  O    . TYR   A 1 102 ? 43.96748 -8.00222  20.04897  1.000 35.29917  ? 102 TYR   A O    1 
ATOM   1816 C  CB   . TYR   A 1 102 ? 42.81380 -5.01867  19.70896  1.000 36.96899  ? 102 TYR   A CB   1 
ATOM   1817 C  CG   . TYR   A 1 102 ? 42.47521 -3.71668  19.01341  1.000 37.54536  ? 102 TYR   A CG   1 
ATOM   1818 C  CD1  . TYR   A 1 102 ? 43.40621 -2.69733  18.91886  1.000 43.62377  ? 102 TYR   A CD1  1 
ATOM   1819 C  CD2  . TYR   A 1 102 ? 41.21639 -3.50397  18.47155  1.000 40.68610  ? 102 TYR   A CD2  1 
ATOM   1820 C  CE1  . TYR   A 1 102 ? 43.09711 -1.50811  18.28523  1.000 45.41509  ? 102 TYR   A CE1  1 
ATOM   1821 C  CE2  . TYR   A 1 102 ? 40.89872 -2.31741  17.83740  1.000 43.70182  ? 102 TYR   A CE2  1 
ATOM   1822 C  CZ   . TYR   A 1 102 ? 41.84583 -1.32473  17.74329  1.000 46.79853  ? 102 TYR   A CZ   1 
ATOM   1823 O  OH   . TYR   A 1 102 ? 41.53277 -0.13681  17.12208  1.000 55.89013  ? 102 TYR   A OH   1 
ATOM   1824 H  H    . TYR   A 1 102 ? 42.59421 -6.34481  17.62671  1.000 49.53486  ? 102 TYR   A H    1 
ATOM   1825 H  HA   . TYR   A 1 102 ? 44.60432 -5.19498  18.77598  1.000 46.16714  ? 102 TYR   A HA   1 
ATOM   1826 H  HB2  . TYR   A 1 102 ? 42.00618 -5.55505  19.73953  1.000 44.37705  ? 102 TYR   A HB2  1 
ATOM   1827 H  HB3  . TYR   A 1 102 ? 43.10429 -4.80479  20.60938  1.000 44.37705  ? 102 TYR   A HB3  1 
ATOM   1828 H  HD1  . TYR   A 1 102 ? 44.25226 -2.81393  19.28696  1.000 52.36279  ? 102 TYR   A HD1  1 
ATOM   1829 H  HD2  . TYR   A 1 102 ? 40.57335 -4.17273  18.53609  1.000 48.83759  ? 102 TYR   A HD2  1 
ATOM   1830 H  HE1  . TYR   A 1 102 ? 43.73402 -0.83308  18.22539  1.000 54.51238  ? 102 TYR   A HE1  1 
ATOM   1831 H  HE2  . TYR   A 1 102 ? 40.05069 -2.19136  17.47704  1.000 52.45645  ? 102 TYR   A HE2  1 
ATOM   1832 H  HH   . TYR   A 1 102 ? 40.73436 -0.15060  16.86141  1.000 67.08243  ? 102 TYR   A HH   1 
ATOM   1833 N  N    . PRO   A 1 103 ? 45.50983 -6.53119  20.73912  1.000 46.26489  ? 103 PRO   A N    1 
ATOM   1834 C  CA   . PRO   A 1 103 ? 46.26111 -7.57726  21.45979  1.000 36.33463  ? 103 PRO   A CA   1 
ATOM   1835 C  C    . PRO   A 1 103 ? 45.45817 -8.33331  22.51134  1.000 30.88523  ? 103 PRO   A C    1 
ATOM   1836 O  O    . PRO   A 1 103 ? 45.81248 -9.47951  22.81762  1.000 40.20365  ? 103 PRO   A O    1 
ATOM   1837 C  CB   . PRO   A 1 103 ? 47.42260 -6.79208  22.09892  1.000 39.43361  ? 103 PRO   A CB   1 
ATOM   1838 C  CG   . PRO   A 1 103 ? 46.96286 -5.36143  22.14409  1.000 45.48792  ? 103 PRO   A CG   1 
ATOM   1839 C  CD   . PRO   A 1 103 ? 46.08648 -5.18354  20.92523  1.000 38.37244  ? 103 PRO   A CD   1 
ATOM   1840 H  HA   . PRO   A 1 103 ? 46.60451 -8.21704  20.81663  1.000 43.61583  ? 103 PRO   A HA   1 
ATOM   1841 H  HB2  . PRO   A 1 103 ? 47.59352 -7.12832  22.99258  1.000 47.33461  ? 103 PRO   A HB2  1 
ATOM   1842 H  HB3  . PRO   A 1 103 ? 48.21917 -6.88180  21.55272  1.000 47.33461  ? 103 PRO   A HB3  1 
ATOM   1843 H  HG2  . PRO   A 1 103 ? 46.45903 -5.20318  22.95773  1.000 54.59977  ? 103 PRO   A HG2  1 
ATOM   1844 H  HG3  . PRO   A 1 103 ? 47.72938 -4.76811  22.10782  1.000 54.59977  ? 103 PRO   A HG3  1 
ATOM   1845 H  HD2  . PRO   A 1 103 ? 45.39095 -4.52787  21.09022  1.000 46.06120  ? 103 PRO   A HD2  1 
ATOM   1846 H  HD3  . PRO   A 1 103 ? 46.61317 -4.92156  20.15396  1.000 46.06120  ? 103 PRO   A HD3  1 
ATOM   1847 N  N    . GLU   A 1 104 ? 44.40179 -7.74505  23.06919  1.000 39.24483  ? 104 GLU   A N    1 
ATOM   1848 C  CA   . GLU   A 1 104 ? 43.67313 -8.38256  24.16499  1.000 39.43902  ? 104 GLU   A CA   1 
ATOM   1849 C  C    . GLU   A 1 104 ? 42.46469 -9.20120  23.70256  1.000 46.42933  ? 104 GLU   A C    1 
ATOM   1850 O  O    . GLU   A 1 104 ? 41.75276 -9.76805  24.54109  1.000 33.11522  ? 104 GLU   A O    1 
ATOM   1851 C  CB   . GLU   A 1 104 ? 43.22489 -7.32553  25.17408  1.000 45.73290  ? 104 GLU   A CB   1 
ATOM   1852 C  CG   . GLU   A 1 104 ? 42.00357 -6.50194  24.79448  1.000 43.79755  ? 104 GLU   A CG   1 
ATOM   1853 C  CD   . GLU   A 1 104 ? 42.31274 -5.34169  23.87483  1.000 35.98460  ? 104 GLU   A CD   1 
ATOM   1854 O  OE1  . GLU   A 1 104 ? 43.37942 -5.35509  23.23071  1.000 37.02775  ? 104 GLU   A OE1  1 
ATOM   1855 O  OE2  . GLU   A 1 104 ? 41.47458 -4.42246  23.79100  1.000 42.84127  ? 104 GLU   A OE2  1 
ATOM   1856 H  H    . GLU   A 1 104 ? 44.08897 -6.97997  22.83171  1.000 47.10807  ? 104 GLU   A H    1 
ATOM   1857 H  HA   . GLU   A 1 104 ? 44.27561 -8.99473  24.61573  1.000 47.34109  ? 104 GLU   A HA   1 
ATOM   1858 H  HB2  . GLU   A 1 104 ? 43.01739 -7.77436  26.00858  1.000 54.89375  ? 104 GLU   A HB2  1 
ATOM   1859 H  HB3  . GLU   A 1 104 ? 43.95792 -6.70391  25.30505  1.000 54.89375  ? 104 GLU   A HB3  1 
ATOM   1860 H  HG2  . GLU   A 1 104 ? 41.36765 -7.07724  24.34111  1.000 52.57133  ? 104 GLU   A HG2  1 
ATOM   1861 H  HG3  . GLU   A 1 104 ? 41.60688 -6.14100  25.60272  1.000 52.57133  ? 104 GLU   A HG3  1 
ATOM   1862 N  N    . VAL   A 1 105 ? 42.23562 -9.31453  22.39961  1.000 35.28994  ? 105 VAL   A N    1 
ATOM   1863 C  CA   . VAL   A 1 105 ? 40.97240 -9.86299  21.91070  1.000 29.69620  ? 105 VAL   A CA   1 
ATOM   1864 C  C    . VAL   A 1 105 ? 40.85184 -11.34268 22.24754  1.000 31.57334  ? 105 VAL   A C    1 
ATOM   1865 O  O    . VAL   A 1 105 ? 39.82784 -11.79207 22.77223  1.000 36.91550  ? 105 VAL   A O    1 
ATOM   1866 C  CB   . VAL   A 1 105 ? 40.83406 -9.62246  20.38702  1.000 30.55895  ? 105 VAL   A CB   1 
ATOM   1867 C  CG1  . VAL   A 1 105 ? 39.66795 -10.45350 19.85094  1.000 39.67500  ? 105 VAL   A CG1  1 
ATOM   1868 C  CG2  . VAL   A 1 105 ? 40.62429 -8.15672  20.10703  1.000 33.12513  ? 105 VAL   A CG2  1 
ATOM   1869 H  H    . VAL   A 1 105 ? 42.78779 -9.08428  21.78180  1.000 42.36220  ? 105 VAL   A H    1 
ATOM   1870 H  HA   . VAL   A 1 105 ? 40.25033 -9.39818  22.36176  1.000 35.64972  ? 105 VAL   A HA   1 
ATOM   1871 H  HB   . VAL   A 1 105 ? 41.64644 -9.89539  19.93265  1.000 36.68501  ? 105 VAL   A HB   1 
ATOM   1872 H  HG11 . VAL   A 1 105 ? 39.39664 -10.09846 18.98999  1.000 47.62427  ? 105 VAL   A HG11 1 
ATOM   1873 H  HG12 . VAL   A 1 105 ? 39.95538 -11.37476 19.75313  1.000 47.62427  ? 105 VAL   A HG12 1 
ATOM   1874 H  HG13 . VAL   A 1 105 ? 38.92927 -10.40222 20.47754  1.000 47.62427  ? 105 VAL   A HG13 1 
ATOM   1875 H  HG21 . VAL   A 1 105 ? 40.55551 -8.02500  19.14848  1.000 39.76443  ? 105 VAL   A HG21 1 
ATOM   1876 H  HG22 . VAL   A 1 105 ? 39.80648 -7.86632  20.54035  1.000 39.76443  ? 105 VAL   A HG22 1 
ATOM   1877 H  HG23 . VAL   A 1 105 ? 41.37899 -7.65733  20.45624  1.000 39.76443  ? 105 VAL   A HG23 1 
ATOM   1878 N  N    . VAL   A 1 106 ? 41.88124 -12.13023 21.93982  1.000 32.16506  ? 106 VAL   A N    1 
ATOM   1879 C  CA   . VAL   A 1 106 ? 41.78147 -13.57486 22.15638  1.000 34.76648  ? 106 VAL   A CA   1 
ATOM   1880 C  C    . VAL   A 1 106 ? 41.55495 -13.87844 23.63606  1.000 39.87816  ? 106 VAL   A C    1 
ATOM   1881 O  O    . VAL   A 1 106 ? 40.73356 -14.73187 23.99285  1.000 38.25150  ? 106 VAL   A O    1 
ATOM   1882 C  CB   . VAL   A 1 106 ? 43.04043 -14.28188 21.62962  1.000 36.37823  ? 106 VAL   A CB   1 
ATOM   1883 C  CG1  . VAL   A 1 106 ? 43.06621 -15.72824 22.07373  1.000 40.22122  ? 106 VAL   A CG1  1 
ATOM   1884 C  CG2  . VAL   A 1 106 ? 43.10053 -14.18527 20.10291  1.000 48.60781  ? 106 VAL   A CG2  1 
ATOM   1885 H  H    . VAL   A 1 106 ? 42.63005 -11.86210 21.61273  1.000 38.61235  ? 106 VAL   A H    1 
ATOM   1886 H  HA   . VAL   A 1 106 ? 41.01719 -13.90592 21.65921  1.000 41.73404  ? 106 VAL   A HA   1 
ATOM   1887 H  HB   . VAL   A 1 106 ? 43.82453 -13.84356 21.99563  1.000 43.66815  ? 106 VAL   A HB   1 
ATOM   1888 H  HG11 . VAL   A 1 106 ? 43.66586 -16.22544 21.49570  1.000 48.27974  ? 106 VAL   A HG11 1 
ATOM   1889 H  HG12 . VAL   A 1 106 ? 43.37929 -15.77147 22.99080  1.000 48.27974  ? 106 VAL   A HG12 1 
ATOM   1890 H  HG13 . VAL   A 1 106 ? 42.16962 -16.09335 22.01274  1.000 48.27974  ? 106 VAL   A HG13 1 
ATOM   1891 H  HG21 . VAL   A 1 106 ? 43.90485 -14.62797 19.78988  1.000 58.34364  ? 106 VAL   A HG21 1 
ATOM   1892 H  HG22 . VAL   A 1 106 ? 42.31753 -14.61800 19.72802  1.000 58.34364  ? 106 VAL   A HG22 1 
ATOM   1893 H  HG23 . VAL   A 1 106 ? 43.11642 -13.25003 19.84604  1.000 58.34364  ? 106 VAL   A HG23 1 
ATOM   1894 N  N    . GLU   A 1 107 ? 42.28175 -13.18602 24.51479  1.000 36.21523  ? 107 GLU   A N    1 
ATOM   1895 C  CA   . GLU   A 1 107 ? 42.10405 -13.37305 25.95551  1.000 43.89059  ? 107 GLU   A CA   1 
ATOM   1896 C  C    . GLU   A 1 107 ? 40.67389 -13.08089 26.38392  1.000 36.34227  ? 107 GLU   A C    1 
ATOM   1897 O  O    . GLU   A 1 107 ? 40.09754 -13.81269 27.20357  1.000 38.93195  ? 107 GLU   A O    1 
ATOM   1898 C  CB   . GLU   A 1 107 ? 43.08413 -12.47109 26.71187  1.000 43.26469  ? 107 GLU   A CB   1 
ATOM   1899 C  CG   . GLU   A 1 107 ? 42.90747 -12.44508 28.22438  1.000 69.76580  ? 107 GLU   A CG   1 
ATOM   1900 C  CD   . GLU   A 1 107 ? 43.69257 -11.31702 28.88602  1.000 85.61541  ? 107 GLU   A CD   1 
ATOM   1901 O  OE1  . GLU   A 1 107 ? 44.75155 -10.92419 28.34843  1.000 50.86032  ? 107 GLU   A OE1  1 
ATOM   1902 O  OE2  . GLU   A 1 107 ? 43.24050 -10.81452 29.93686  1.000 81.69489  ? 107 GLU   A OE2  1 
ATOM   1903 H  H    . GLU   A 1 107 ? 42.88064 -12.60546 24.30533  1.000 43.47255  ? 107 GLU   A H    1 
ATOM   1904 H  HA   . GLU   A 1 107 ? 42.29636 -14.29701 26.17962  1.000 52.68298  ? 107 GLU   A HA   1 
ATOM   1905 H  HB2  . GLU   A 1 107 ? 43.98587 -12.77918 26.53063  1.000 51.93190  ? 107 GLU   A HB2  1 
ATOM   1906 H  HB3  . GLU   A 1 107 ? 42.97337 -11.56227 26.39145  1.000 51.93190  ? 107 GLU   A HB3  1 
ATOM   1907 H  HG2  . GLU   A 1 107 ? 41.96820 -12.31958 28.43156  1.000 83.73324  ? 107 GLU   A HG2  1 
ATOM   1908 H  HG3  . GLU   A 1 107 ? 43.21934 -13.28579 28.59431  1.000 83.73324  ? 107 GLU   A HG3  1 
ATOM   1909 N  N    . VAL   A 1 108 ? 40.09690 -11.99745 25.87077  1.000 34.92535  ? 108 VAL   A N    1 
ATOM   1910 C  CA   . VAL   A 1 108 ? 38.77581 -11.56780 26.30881  1.000 33.40315  ? 108 VAL   A CA   1 
ATOM   1911 C  C    . VAL   A 1 108 ? 37.70811 -12.54201 25.83431  1.000 38.17914  ? 108 VAL   A C    1 
ATOM   1912 O  O    . VAL   A 1 108 ? 36.81959 -12.92922 26.59903  1.000 34.37156  ? 108 VAL   A O    1 
ATOM   1913 C  CB   . VAL   A 1 108 ? 38.49897 -10.13818 25.82082  1.000 34.56965  ? 108 VAL   A CB   1 
ATOM   1914 C  CG1  . VAL   A 1 108 ? 37.03045 -9.79565  25.96928  1.000 38.11940  ? 108 VAL   A CG1  1 
ATOM   1915 C  CG2  . VAL   A 1 108 ? 39.36582 -9.14854  26.61267  1.000 39.66070  ? 108 VAL   A CG2  1 
ATOM   1916 H  H    . VAL   A 1 108 ? 40.44940 -11.49485 25.26849  1.000 41.92469  ? 108 VAL   A H    1 
ATOM   1917 H  HA   . VAL   A 1 108 ? 38.75670 -11.56578 27.27862  1.000 40.09805  ? 108 VAL   A HA   1 
ATOM   1918 H  HB   . VAL   A 1 108 ? 38.72394 -10.07095 24.87967  1.000 41.49785  ? 108 VAL   A HB   1 
ATOM   1919 H  HG11 . VAL   A 1 108 ? 36.92254 -8.83376  25.90580  1.000 45.75755  ? 108 VAL   A HG11 1 
ATOM   1920 H  HG12 . VAL   A 1 108 ? 36.53126 -10.23195 25.26121  1.000 45.75755  ? 108 VAL   A HG12 1 
ATOM   1921 H  HG13 . VAL   A 1 108 ? 36.71935 -10.10708 26.83364  1.000 45.75755  ? 108 VAL   A HG13 1 
ATOM   1922 H  HG21 . VAL   A 1 108 ? 39.09215 -8.24397  26.39414  1.000 47.60711  ? 108 VAL   A HG21 1 
ATOM   1923 H  HG22 . VAL   A 1 108 ? 39.24411 -9.31090  27.56121  1.000 47.60711  ? 108 VAL   A HG22 1 
ATOM   1924 H  HG23 . VAL   A 1 108 ? 40.29603 -9.28014  26.37124  1.000 47.60711  ? 108 VAL   A HG23 1 
ATOM   1925 N  N    . LEU   A 1 109 ? 37.76184 -12.94001 24.55580  1.000 31.94532  ? 109 LEU   A N    1 
ATOM   1926 C  CA   . LEU   A 1 109 ? 36.78447 -13.89740 24.05821  1.000 33.79700  ? 109 LEU   A CA   1 
ATOM   1927 C  C    . LEU   A 1 109 ? 36.85143 -15.20970 24.83364  1.000 34.68928  ? 109 LEU   A C    1 
ATOM   1928 O  O    . LEU   A 1 109 ? 35.81492 -15.76912 25.21373  1.000 36.02727  ? 109 LEU   A O    1 
ATOM   1929 C  CB   . LEU   A 1 109 ? 37.00368 -14.14215 22.56498  1.000 34.10190  ? 109 LEU   A CB   1 
ATOM   1930 C  CG   . LEU   A 1 109 ? 36.80100 -12.92861 21.67556  1.000 27.50926  ? 109 LEU   A CG   1 
ATOM   1931 C  CD1  . LEU   A 1 109 ? 37.01413 -13.28794 20.19270  1.000 30.67373  ? 109 LEU   A CD1  1 
ATOM   1932 C  CD2  . LEU   A 1 109 ? 35.44175 -12.31225 21.86800  1.000 28.29011  ? 109 LEU   A CD2  1 
ATOM   1933 H  H    . LEU   A 1 109 ? 38.34011 -12.67485 23.97710  1.000 38.34866  ? 109 LEU   A H    1 
ATOM   1934 H  HA   . LEU   A 1 109 ? 35.89584 -13.52622 24.17417  1.000 40.57068  ? 109 LEU   A HA   1 
ATOM   1935 H  HB2  . LEU   A 1 109 ? 37.91498 -14.44836 22.43593  1.000 40.93655  ? 109 LEU   A HB2  1 
ATOM   1936 H  HB3  . LEU   A 1 109 ? 36.37974 -14.82473 22.27225  1.000 40.93655  ? 109 LEU   A HB3  1 
ATOM   1937 H  HG   . LEU   A 1 109 ? 37.46223 -12.26625 21.93041  1.000 33.02538  ? 109 LEU   A HG   1 
ATOM   1938 H  HD11 . LEU   A 1 109 ? 36.89102 -12.49089 19.65377  1.000 36.82275  ? 109 LEU   A HD11 1 
ATOM   1939 H  HD12 . LEU   A 1 109 ? 37.91448 -13.62976 20.07685  1.000 36.82275  ? 109 LEU   A HD12 1 
ATOM   1940 H  HD13 . LEU   A 1 109 ? 36.36795 -13.96414 19.93559  1.000 36.82275  ? 109 LEU   A HD13 1 
ATOM   1941 H  HD21 . LEU   A 1 109 ? 35.28574 -11.66503 21.16254  1.000 33.96241  ? 109 LEU   A HD21 1 
ATOM   1942 H  HD22 . LEU   A 1 109 ? 34.76997 -13.01095 21.83037  1.000 33.96241  ? 109 LEU   A HD22 1 
ATOM   1943 H  HD23 . LEU   A 1 109 ? 35.41380 -11.87271 22.73225  1.000 33.96241  ? 109 LEU   A HD23 1 
ATOM   1944 N  N    . LYS   A 1 110 ? 38.05924 -15.70852 25.09476  1.000 40.46885  ? 110 LYS   A N    1 
ATOM   1945 C  CA   . LYS   A 1 110 ? 38.19106 -16.96378 25.83274  1.000 37.04751  ? 110 LYS   A CA   1 
ATOM   1946 C  C    . LYS   A 1 110 ? 37.65879 -16.83485 27.25897  1.000 49.24674  ? 110 LYS   A C    1 
ATOM   1947 O  O    . LYS   A 1 110 ? 37.02409 -17.76035 27.77649  1.000 42.36285  ? 110 LYS   A O    1 
ATOM   1948 C  CB   . LYS   A 1 110 ? 39.65118 -17.41653 25.84990  1.000 39.15649  ? 110 LYS   A CB   1 
ATOM   1949 C  CG   . LYS   A 1 110 ? 40.16760 -17.85750 24.47703  1.000 42.63934  ? 110 LYS   A CG   1 
ATOM   1950 C  CD   . LYS   A 1 110 ? 41.61684 -18.32838 24.52302  1.000 42.11436  ? 110 LYS   A CD   1 
ATOM   1951 C  CE   . LYS   A 1 110 ? 41.78450 -19.62518 25.29277  1.000 50.80170  ? 110 LYS   A CE   1 
ATOM   1952 N  NZ   . LYS   A 1 110 ? 40.83824 -20.68549 24.84643  1.000 67.49318  ? 110 LYS   A NZ   1 
ATOM   1953 H  H    . LYS   A 1 110 ? 38.80400 -15.34768 24.86084  1.000 48.57689  ? 110 LYS   A H    1 
ATOM   1954 H  HA   . LYS   A 1 110 ? 37.66866 -17.64238 25.37722  1.000 44.47128  ? 110 LYS   A HA   1 
ATOM   1955 H  HB2  . LYS   A 1 110 ? 40.20405 -16.67947 26.15318  1.000 47.00206  ? 110 LYS   A HB2  1 
ATOM   1956 H  HB3  . LYS   A 1 110 ? 39.73879 -18.16843 26.45643  1.000 47.00206  ? 110 LYS   A HB3  1 
ATOM   1957 H  HG2  . LYS   A 1 110 ? 39.62285 -18.59213 24.15381  1.000 51.18148  ? 110 LYS   A HG2  1 
ATOM   1958 H  HG3  . LYS   A 1 110 ? 40.11395 -17.10915 23.86221  1.000 51.18148  ? 110 LYS   A HG3  1 
ATOM   1959 H  HD2  . LYS   A 1 110 ? 41.93181 -18.47409 23.61722  1.000 50.55150  ? 110 LYS   A HD2  1 
ATOM   1960 H  HD3  . LYS   A 1 110 ? 42.15715 -17.64969 24.95700  1.000 50.55150  ? 110 LYS   A HD3  1 
ATOM   1961 H  HE2  . LYS   A 1 110 ? 42.68741 -19.95534 25.16372  1.000 60.97632  ? 110 LYS   A HE2  1 
ATOM   1962 H  HE3  . LYS   A 1 110 ? 41.62412 -19.45719 26.23455  1.000 60.97632  ? 110 LYS   A HE3  1 
ATOM   1963 H  HZ1  . LYS   A 1 110 ? 41.05120 -21.46243 25.22473  1.000 81.00608  ? 110 LYS   A HZ1  1 
ATOM   1964 H  HZ2  . LYS   A 1 110 ? 40.00689 -20.46917 25.07917  1.000 81.00608  ? 110 LYS   A HZ2  1 
ATOM   1965 H  HZ3  . LYS   A 1 110 ? 40.87652 -20.77489 23.96176  1.000 81.00608  ? 110 LYS   A HZ3  1 
ATOM   1966 N  N    . SER   A 1 111 ? 37.90191 -15.69530 27.90846  1.000 39.43136  ? 111 SER   A N    1 
ATOM   1967 C  CA   . SER   A 1 111 ? 37.44786 -15.52559 29.28333  1.000 39.23885  ? 111 SER   A CA   1 
ATOM   1968 C  C    . SER   A 1 111 ? 35.92793 -15.48362 29.36085  1.000 44.19708  ? 111 SER   A C    1 
ATOM   1969 O  O    . SER   A 1 111 ? 35.34313 -15.90950 30.36101  1.000 51.81154  ? 111 SER   A O    1 
ATOM   1970 C  CB   . SER   A 1 111 ? 38.04136 -14.25227 29.88751  1.000 46.64169  ? 111 SER   A CB   1 
ATOM   1971 O  OG   . SER   A 1 111 ? 37.44185 -13.09279 29.33330  1.000 51.07787  ? 111 SER   A OG   1 
ATOM   1972 H  H    . SER   A 1 111 ? 38.31985 -15.01906 27.58041  1.000 47.33190  ? 111 SER   A H    1 
ATOM   1973 H  HA   . SER   A 1 111 ? 37.76207 -16.27712 29.81000  1.000 47.10089  ? 111 SER   A HA   1 
ATOM   1974 H  HB2  . SER   A 1 111 ? 37.88805 -14.25797 30.84530  1.000 55.98430  ? 111 SER   A HB2  1 
ATOM   1975 H  HB3  . SER   A 1 111 ? 38.99364 -14.23180 29.70407  1.000 55.98430  ? 111 SER   A HB3  1 
ATOM   1976 H  HG   . SER   A 1 111 ? 37.56821 -13.07290 28.50310  1.000 61.30771  ? 111 SER   A HG   1 
ATOM   1977 N  N    . LEU   A 1 112 ? 35.27584 -14.96706 28.32681  1.000 35.79185  ? 112 LEU   A N    1 
ATOM   1978 C  CA   . LEU   A 1 112 ? 33.82723 -14.85883 28.33297  1.000 41.83631  ? 112 LEU   A CA   1 
ATOM   1979 C  C    . LEU   A 1 112 ? 33.15564 -16.15597 27.90948  1.000 44.30845  ? 112 LEU   A C    1 
ATOM   1980 O  O    . LEU   A 1 112 ? 32.05087 -16.44997 28.36898  1.000 38.80629  ? 112 LEU   A O    1 
ATOM   1981 C  CB   . LEU   A 1 112 ? 33.38241 -13.74129 27.39342  1.000 39.56522  ? 112 LEU   A CB   1 
ATOM   1982 C  CG   . LEU   A 1 112 ? 33.74857 -12.30891 27.75566  1.000 38.34757  ? 112 LEU   A CG   1 
ATOM   1983 C  CD1  . LEU   A 1 112 ? 33.47349 -11.38972 26.59012  1.000 45.39583  ? 112 LEU   A CD1  1 
ATOM   1984 C  CD2  . LEU   A 1 112 ? 32.95868 -11.87508 28.96844  1.000 40.01384  ? 112 LEU   A CD2  1 
ATOM   1985 H  H    . LEU   A 1 112 ? 35.64957 -14.67245 27.61047  1.000 42.96449  ? 112 LEU   A H    1 
ATOM   1986 H  HA   . LEU   A 1 112 ? 33.54148 -14.64156 29.23410  1.000 50.21785  ? 112 LEU   A HA   1 
ATOM   1987 H  HB2  . LEU   A 1 112 ? 33.77333 -13.91622 26.52309  1.000 47.49253  ? 112 LEU   A HB2  1 
ATOM   1988 H  HB3  . LEU   A 1 112 ? 32.41472 -13.77428 27.33515  1.000 47.49253  ? 112 LEU   A HB3  1 
ATOM   1989 H  HG   . LEU   A 1 112 ? 34.69416 -12.25444 27.96492  1.000 46.03135  ? 112 LEU   A HG   1 
ATOM   1990 H  HD11 . LEU   A 1 112 ? 33.69563 -10.48070 26.84554  1.000 54.48927  ? 112 LEU   A HD11 1 
ATOM   1991 H  HD12 . LEU   A 1 112 ? 34.01859 -11.66402 25.83611  1.000 54.48927  ? 112 LEU   A HD12 1 
ATOM   1992 H  HD13 . LEU   A 1 112 ? 32.53364 -11.44759 26.35725  1.000 54.48927  ? 112 LEU   A HD13 1 
ATOM   1993 H  HD21 . LEU   A 1 112 ? 33.23488 -10.98040 29.22173  1.000 48.03088  ? 112 LEU   A HD21 1 
ATOM   1994 H  HD22 . LEU   A 1 112 ? 32.01400 -11.87974 28.74828  1.000 48.03088  ? 112 LEU   A HD22 1 
ATOM   1995 H  HD23 . LEU   A 1 112 ? 33.13187 -12.49308 29.69575  1.000 48.03088  ? 112 LEU   A HD23 1 
ATOM   1996 N  N    . LYS   A 1 113 ? 33.80035 -16.93036 27.03268  1.000 49.07485  ? 113 LYS   A N    1 
ATOM   1997 C  CA   . LYS   A 1 113 ? 33.11151 -18.02678 26.36144  1.000 40.56515  ? 113 LYS   A CA   1 
ATOM   1998 C  C    . LYS   A 1 113 ? 32.62387 -19.07456 27.34629  1.000 36.40333  ? 113 LYS   A C    1 
ATOM   1999 O  O    . LYS   A 1 113 ? 31.63689 -19.77263 27.07385  1.000 58.31100  ? 113 LYS   A O    1 
ATOM   2000 C  CB   . LYS   A 1 113 ? 34.03604 -18.67407 25.33401  1.000 43.30634  ? 113 LYS   A CB   1 
ATOM   2001 C  CG   . LYS   A 1 113 ? 33.35558 -19.71705 24.45806  1.000 66.15936  ? 113 LYS   A CG   1 
ATOM   2002 C  CD   . LYS   A 1 113 ? 34.31784 -20.25404 23.39921  1.000 68.95989  ? 113 LYS   A CD   1 
ATOM   2003 C  CE   . LYS   A 1 113 ? 33.68623 -21.36437 22.55819  1.000 53.91720  ? 113 LYS   A CE   1 
ATOM   2004 N  NZ   . LYS   A 1 113 ? 32.39352 -20.96542 21.94473  1.000 57.62012  ? 113 LYS   A NZ   1 
ATOM   2005 H  H    . LYS   A 1 113 ? 34.62700 -16.84116 26.81294  1.000 58.90410  ? 113 LYS   A H    1 
ATOM   2006 H  HA   . LYS   A 1 113 ? 32.34012 -17.66556 25.89735  1.000 48.69245  ? 113 LYS   A HA   1 
ATOM   2007 H  HB2  . LYS   A 1 113 ? 34.38579 -17.98208 24.75114  1.000 51.98188  ? 113 LYS   A HB2  1 
ATOM   2008 H  HB3  . LYS   A 1 113 ? 34.76360 -19.11189 25.80290  1.000 51.98188  ? 113 LYS   A HB3  1 
ATOM   2009 H  HG2  . LYS   A 1 113 ? 33.06005 -20.45879 25.00886  1.000 79.40550  ? 113 LYS   A HG2  1 
ATOM   2010 H  HG3  . LYS   A 1 113 ? 32.59633 -19.31526 24.00750  1.000 79.40550  ? 113 LYS   A HG3  1 
ATOM   2011 H  HD2  . LYS   A 1 113 ? 34.57271 -19.53175 22.80404  1.000 82.76614  ? 113 LYS   A HD2  1 
ATOM   2012 H  HD3  . LYS   A 1 113 ? 35.10401 -20.61632 23.83691  1.000 82.76614  ? 113 LYS   A HD3  1 
ATOM   2013 H  HE2  . LYS   A 1 113 ? 34.29552 -21.60268 21.84205  1.000 64.71491  ? 113 LYS   A HE2  1 
ATOM   2014 H  HE3  . LYS   A 1 113 ? 33.52266 -22.13459 23.12470  1.000 64.71491  ? 113 LYS   A HE3  1 
ATOM   2015 H  HZ1  . LYS   A 1 113 ? 32.07647 -21.62935 21.44396  1.000 69.15842  ? 113 LYS   A HZ1  1 
ATOM   2016 H  HZ2  . LYS   A 1 113 ? 31.80077 -20.77482 22.58066  1.000 69.15842  ? 113 LYS   A HZ2  1 
ATOM   2017 H  HZ3  . LYS   A 1 113 ? 32.50863 -20.24681 21.43242  1.000 69.15842  ? 113 LYS   A HZ3  1 
ATOM   2018 N  N    . GLY   A 1 114 ? 33.29542 -19.20440 28.49067  1.000 39.71624  ? 114 GLY   A N    1 
ATOM   2019 C  CA   . GLY   A 1 114 ? 32.91357 -20.23019 29.44774  1.000 42.18834  ? 114 GLY   A CA   1 
ATOM   2020 C  C    . GLY   A 1 114 ? 31.65547 -19.92687 30.23214  1.000 43.73743  ? 114 GLY   A C    1 
ATOM   2021 O  O    . GLY   A 1 114 ? 31.00812 -20.85538 30.72256  1.000 49.97137  ? 114 GLY   A O    1 
ATOM   2022 H  H    . GLY   A 1 114 ? 33.96342 -18.71799 28.72897  1.000 47.67376  ? 114 GLY   A H    1 
ATOM   2023 H  HA2  . GLY   A 1 114 ? 32.77199 -21.06327 28.97148  1.000 50.64028  ? 114 GLY   A HA2  1 
ATOM   2024 H  HA3  . GLY   A 1 114 ? 33.63719 -20.34850 30.08278  1.000 50.64028  ? 114 GLY   A HA3  1 
ATOM   2025 N  N    . LYS   A 1 115 ? 31.28123 -18.65685 30.33578  1.000 48.66389  ? 115 LYS   A N    1 
ATOM   2026 C  CA   . LYS   A 1 115 ? 30.21514 -18.22408 31.22498  1.000 45.56653  ? 115 LYS   A CA   1 
ATOM   2027 C  C    . LYS   A 1 115 ? 29.08513 -17.49678 30.50882  1.000 42.61785  ? 115 LYS   A C    1 
ATOM   2028 O  O    . LYS   A 1 115 ? 28.01430 -17.31515 31.10412  1.000 38.17369  ? 115 LYS   A O    1 
ATOM   2029 C  CB   . LYS   A 1 115 ? 30.76498 -17.28159 32.32195  1.000 52.15972  ? 115 LYS   A CB   1 
ATOM   2030 C  CG   . LYS   A 1 115 ? 32.21673 -17.52581 32.72799  1.000 60.94877  ? 115 LYS   A CG   1 
ATOM   2031 C  CD   . LYS   A 1 115 ? 32.32978 -18.20034 34.09536  1.000 105.88540 ? 115 LYS   A CD   1 
ATOM   2032 C  CE   . LYS   A 1 115 ? 33.77205 -18.59702 34.39474  1.000 103.76540 ? 115 LYS   A CE   1 
ATOM   2033 N  NZ   . LYS   A 1 115 ? 34.34569 -19.49900 33.34043  1.000 88.53865  ? 115 LYS   A NZ   1 
ATOM   2034 H  H    . LYS   A 1 115 ? 31.63878 -18.01376 29.89057  1.000 58.41094  ? 115 LYS   A H    1 
ATOM   2035 H  HA   . LYS   A 1 115 ? 29.84989 -19.01098 31.65890  1.000 54.69411  ? 115 LYS   A HA   1 
ATOM   2036 H  HB2  . LYS   A 1 115 ? 30.70477 -16.36898 31.99880  1.000 62.60594  ? 115 LYS   A HB2  1 
ATOM   2037 H  HB3  . LYS   A 1 115 ? 30.22038 -17.38845 33.11749  1.000 62.60594  ? 115 LYS   A HB3  1 
ATOM   2038 H  HG2  . LYS   A 1 115 ? 32.63835 -18.10215 32.07151  1.000 73.15279  ? 115 LYS   A HG2  1 
ATOM   2039 H  HG3  . LYS   A 1 115 ? 32.68252 -16.67608 32.77135  1.000 73.15279  ? 115 LYS   A HG3  1 
ATOM   2040 H  HD2  . LYS   A 1 115 ? 32.03166 -17.58579 34.78409  1.000 127.07675 ? 115 LYS   A HD2  1 
ATOM   2041 H  HD3  . LYS   A 1 115 ? 31.78299 -19.00147 34.10628  1.000 127.07675 ? 115 LYS   A HD3  1 
ATOM   2042 H  HE2  . LYS   A 1 115 ? 34.31939 -17.79736 34.43793  1.000 124.53275 ? 115 LYS   A HE2  1 
ATOM   2043 H  HE3  . LYS   A 1 115 ? 33.80321 -19.06659 35.24293  1.000 124.53275 ? 115 LYS   A HE3  1 
ATOM   2044 H  HZ1  . LYS   A 1 115 ? 35.18632 -19.70888 33.54388  1.000 106.26065 ? 115 LYS   A HZ1  1 
ATOM   2045 H  HZ2  . LYS   A 1 115 ? 33.86634 -20.24690 33.28598  1.000 106.26065 ? 115 LYS   A HZ2  1 
ATOM   2046 H  HZ3  . LYS   A 1 115 ? 34.33331 -19.08982 32.55016  1.000 106.26065 ? 115 LYS   A HZ3  1 
ATOM   2047 N  N    . TYR   A 1 116 ? 29.29147 -17.06728 29.26074  1.000 32.41045  ? 116 TYR   A N    1 
ATOM   2048 C  CA   . TYR   A 1 116 ? 28.30247 -16.32055 28.51593  1.000 30.89342  ? 116 TYR   A CA   1 
ATOM   2049 C  C    . TYR   A 1 116 ? 28.23339 -16.87247 27.09246  1.000 27.66695  ? 116 TYR   A C    1 
ATOM   2050 O  O    . TYR   A 1 116 ? 29.16707 -17.52216 26.61344  1.000 33.80498  ? 116 TYR   A O    1 
ATOM   2051 C  CB   . TYR   A 1 116 ? 28.63382 -14.81958 28.45240  1.000 32.42765  ? 116 TYR   A CB   1 
ATOM   2052 C  CG   . TYR   A 1 116 ? 28.83056 -14.12707 29.78968  1.000 36.96738  ? 116 TYR   A CG   1 
ATOM   2053 C  CD1  . TYR   A 1 116 ? 30.03762 -14.21126 30.46274  1.000 40.17361  ? 116 TYR   A CD1  1 
ATOM   2054 C  CD2  . TYR   A 1 116 ? 27.80899 -13.39099 30.36418  1.000 48.79699  ? 116 TYR   A CD2  1 
ATOM   2055 C  CE1  . TYR   A 1 116 ? 30.22309 -13.58919 31.69002  1.000 42.08970  ? 116 TYR   A CE1  1 
ATOM   2056 C  CE2  . TYR   A 1 116 ? 27.98329 -12.75604 31.60096  1.000 44.32991  ? 116 TYR   A CE2  1 
ATOM   2057 C  CZ   . TYR   A 1 116 ? 29.19553 -12.86253 32.24712  1.000 46.79457  ? 116 TYR   A CZ   1 
ATOM   2058 O  OH   . TYR   A 1 116 ? 29.37738 -12.24214 33.46230  1.000 53.64656  ? 116 TYR   A OH   1 
ATOM   2059 H  H    . TYR   A 1 116 ? 30.01793 -17.20440 28.82136  1.000 38.90681  ? 116 TYR   A H    1 
ATOM   2060 H  HA   . TYR   A 1 116 ? 27.44071 -16.42939 28.94770  1.000 37.08638  ? 116 TYR   A HA   1 
ATOM   2061 H  HB2  . TYR   A 1 116 ? 29.45609 -14.71121 27.94937  1.000 38.92745  ? 116 TYR   A HB2  1 
ATOM   2062 H  HB3  . TYR   A 1 116 ? 27.90551 -14.36680 27.99914  1.000 38.92745  ? 116 TYR   A HB3  1 
ATOM   2063 H  HD1  . TYR   A 1 116 ? 30.73750 -14.69372 30.08552  1.000 48.22260  ? 116 TYR   A HD1  1 
ATOM   2064 H  HD2  . TYR   A 1 116 ? 26.99403 -13.31665 29.92236  1.000 58.57066  ? 116 TYR   A HD2  1 
ATOM   2065 H  HE1  . TYR   A 1 116 ? 31.03730 -13.66312 32.13329  1.000 50.52192  ? 116 TYR   A HE1  1 
ATOM   2066 H  HE2  . TYR   A 1 116 ? 27.28877 -12.26833 31.98133  1.000 53.21017  ? 116 TYR   A HE2  1 
ATOM   2067 H  HH   . TYR   A 1 116 ? 30.15595 -12.38427 33.74378  1.000 64.39014  ? 116 TYR   A HH   1 
ATOM   2068 N  N    . HIS   A 1 117 ? 27.12033 -16.59395 26.41645  1.000 28.82040  ? 117 HIS   A N    1 
ATOM   2069 C  CA   . HIS   A 1 117 ? 27.08236 -16.74051 24.95983  1.000 31.47766  ? 117 HIS   A CA   1 
ATOM   2070 C  C    . HIS   A 1 117 ? 27.86806 -15.59934 24.31998  1.000 36.23501  ? 117 HIS   A C    1 
ATOM   2071 O  O    . HIS   A 1 117 ? 27.48814 -14.43055 24.45389  1.000 32.49035  ? 117 HIS   A O    1 
ATOM   2072 C  CB   . HIS   A 1 117 ? 25.64797 -16.72648 24.45189  1.000 28.67282  ? 117 HIS   A CB   1 
ATOM   2073 C  CG   . HIS   A 1 117 ? 25.51958 -16.88964 22.96002  1.000 28.90393  ? 117 HIS   A CG   1 
ATOM   2074 N  ND1  . HIS   A 1 117 ? 25.21678 -18.08922 22.36621  1.000 28.92543  ? 117 HIS   A ND1  1 
ATOM   2075 C  CD2  . HIS   A 1 117 ? 25.66083 -15.99950 21.94786  1.000 31.05450  ? 117 HIS   A CD2  1 
ATOM   2076 C  CE1  . HIS   A 1 117 ? 25.18426 -17.94080 21.05041  1.000 29.39522  ? 117 HIS   A CE1  1 
ATOM   2077 N  NE2  . HIS   A 1 117 ? 25.44262 -16.67720 20.76985  1.000 30.71601  ? 117 HIS   A NE2  1 
ATOM   2078 H  H    . HIS   A 1 117 ? 26.38493 -16.32278 26.77036  1.000 34.59875  ? 117 HIS   A H    1 
ATOM   2079 H  HA   . HIS   A 1 117 ? 27.48171 -17.59015 24.71586  1.000 37.78746  ? 117 HIS   A HA   1 
ATOM   2080 H  HB2  . HIS   A 1 117 ? 25.16364 -17.45537 24.87027  1.000 34.42166  ? 117 HIS   A HB2  1 
ATOM   2081 H  HB3  . HIS   A 1 117 ? 25.24254 -15.87833 24.69100  1.000 34.42166  ? 117 HIS   A HB3  1 
ATOM   2082 H  HD1  . HIS   A 1 117 ? 25.07030 -18.82591 22.78506  1.000 34.72479  ? 117 HIS   A HD1  1 
ATOM   2083 H  HD2  . HIS   A 1 117 ? 25.86724 -15.09675 22.03350  1.000 37.27967  ? 117 HIS   A HD2  1 
ATOM   2084 H  HE1  . HIS   A 1 117 ? 25.00939 -18.61176 20.43062  1.000 35.28854  ? 117 HIS   A HE1  1 
ATOM   2085 N  N    . VAL   A 1 118 ? 28.96664 -15.93245 23.64973  1.000 31.47602  ? 118 VAL   A N    1 
ATOM   2086 C  CA   . VAL   A 1 118 ? 29.81039 -14.94188 22.97724  1.000 29.55665  ? 118 VAL   A CA   1 
ATOM   2087 C  C    . VAL   A 1 118 ? 29.46606 -14.94516 21.49543  1.000 29.07762  ? 118 VAL   A C    1 
ATOM   2088 O  O    . VAL   A 1 118 ? 29.63359 -15.96049 20.79972  1.000 27.66804  ? 118 VAL   A O    1 
ATOM   2089 C  CB   . VAL   A 1 118 ? 31.29916 -15.23515 23.20420  1.000 31.26997  ? 118 VAL   A CB   1 
ATOM   2090 C  CG1  . VAL   A 1 118 ? 32.17505 -14.25574 22.44938  1.000 30.09824  ? 118 VAL   A CG1  1 
ATOM   2091 C  CG2  . VAL   A 1 118 ? 31.60523 -15.19743 24.71122  1.000 35.33376  ? 118 VAL   A CG2  1 
ATOM   2092 H  H    . VAL   A 1 118 ? 29.25107 -16.73987 23.56745  1.000 37.78550  ? 118 VAL   A H    1 
ATOM   2093 H  HA   . VAL   A 1 118 ? 29.61389 -14.05968 23.32938  1.000 35.48225  ? 118 VAL   A HA   1 
ATOM   2094 H  HB   . VAL   A 1 118 ? 31.50410 -16.11986 22.86333  1.000 37.53823  ? 118 VAL   A HB   1 
ATOM   2095 H  HG11 . VAL   A 1 118 ? 33.09250 -14.35805 22.74724  1.000 36.13216  ? 118 VAL   A HG11 1 
ATOM   2096 H  HG12 . VAL   A 1 118 ? 32.11272 -14.44329 21.49972  1.000 36.13216  ? 118 VAL   A HG12 1 
ATOM   2097 H  HG13 . VAL   A 1 118 ? 31.86754 -13.35352 22.62924  1.000 36.13216  ? 118 VAL   A HG13 1 
ATOM   2098 H  HG21 . VAL   A 1 118 ? 32.55409 -15.34828 24.84463  1.000 42.41478  ? 118 VAL   A HG21 1 
ATOM   2099 H  HG22 . VAL   A 1 118 ? 31.35587 -14.32832 25.06246  1.000 42.41478  ? 118 VAL   A HG22 1 
ATOM   2100 H  HG23 . VAL   A 1 118 ? 31.09423 -15.89246 25.15474  1.000 42.41478  ? 118 VAL   A HG23 1 
ATOM   2101 N  N    . GLY   A 1 119 ? 28.96869 -13.81522 21.00912  1.000 26.24147  ? 119 GLY   A N    1 
ATOM   2102 C  CA   . GLY   A 1 119 ? 28.51615 -13.69819 19.63381  1.000 27.59730  ? 119 GLY   A CA   1 
ATOM   2103 C  C    . GLY   A 1 119 ? 29.23967 -12.61424 18.85690  1.000 29.23074  ? 119 GLY   A C    1 
ATOM   2104 O  O    . GLY   A 1 119 ? 29.74643 -11.64730 19.42752  1.000 28.48383  ? 119 GLY   A O    1 
ATOM   2105 H  H    . GLY   A 1 119 ? 28.88238 -13.09124 21.46520  1.000 31.50403  ? 119 GLY   A H    1 
ATOM   2106 H  HA2  . GLY   A 1 119 ? 28.65954 -14.54265 19.17859  1.000 33.13103  ? 119 GLY   A HA2  1 
ATOM   2107 H  HA3  . GLY   A 1 119 ? 27.56818 -13.49276 19.62704  1.000 33.13103  ? 119 GLY   A HA3  1 
ATOM   2108 N  N    . ASP   A 1 120 ? 29.27815 -12.78121 17.53553  1.000 29.26954  ? 120 ASP   A N    1 
ATOM   2109 C  CA   . ASP   A 1 120 ? 29.77302 -11.77013 16.61741  1.000 30.56839  ? 120 ASP   A CA   1 
ATOM   2110 C  C    . ASP   A 1 120 ? 28.61299 -11.29134 15.75985  1.000 32.30593  ? 120 ASP   A C    1 
ATOM   2111 O  O    . ASP   A 1 120 ? 27.76213 -12.08675 15.33706  1.000 33.56898  ? 120 ASP   A O    1 
ATOM   2112 C  CB   . ASP   A 1 120 ? 30.88857 -12.32465 15.73214  1.000 26.78324  ? 120 ASP   A CB   1 
ATOM   2113 C  CG   . ASP   A 1 120 ? 31.80145 -11.25251 15.18130  1.000 41.40792  ? 120 ASP   A CG   1 
ATOM   2114 O  OD1  . ASP   A 1 120 ? 31.74788 -10.09965 15.64645  1.000 35.57481  ? 120 ASP   A OD1  1 
ATOM   2115 O  OD2  . ASP   A 1 120 ? 32.58422 -11.57031 14.26102  1.000 36.59320  ? 120 ASP   A OD2  1 
ATOM   2116 H  H    . ASP   A 1 120 ? 29.01319 -13.49700 17.13925  1.000 35.13772  ? 120 ASP   A H    1 
ATOM   2117 H  HA   . ASP   A 1 120 ? 30.13858 -11.01765 17.10837  1.000 36.69634  ? 120 ASP   A HA   1 
ATOM   2118 H  HB2  . ASP   A 1 120 ? 31.42963 -12.93691 16.25491  1.000 32.15416  ? 120 ASP   A HB2  1 
ATOM   2119 H  HB3  . ASP   A 1 120 ? 30.49073 -12.79198 14.98099  1.000 32.15416  ? 120 ASP   A HB3  1 
ATOM   2120 N  N    . ILE   A 1 121 ? 28.56097 -9.98677  15.52902  1.000 28.93438  ? 121 ILE   A N    1 
ATOM   2121 C  CA   . ILE   A 1 121 ? 27.52972 -9.36595  14.70558  1.000 28.38940  ? 121 ILE   A CA   1 
ATOM   2122 C  C    . ILE   A 1 121 ? 28.26529 -8.54504  13.64975  1.000 33.25487  ? 121 ILE   A C    1 
ATOM   2123 O  O    . ILE   A 1 121 ? 28.95461 -7.57352  13.98736  1.000 36.33431  ? 121 ILE   A O    1 
ATOM   2124 C  CB   . ILE   A 1 121 ? 26.56624 -8.50023  15.52677  1.000 32.77109  ? 121 ILE   A CB   1 
ATOM   2125 C  CG1  . ILE   A 1 121 ? 25.90789 -9.35683  16.62090  1.000 32.73912  ? 121 ILE   A CG1  1 
ATOM   2126 C  CG2  . ILE   A 1 121 ? 25.51941 -7.86864  14.63255  1.000 36.14407  ? 121 ILE   A CG2  1 
ATOM   2127 C  CD1  . ILE   A 1 121 ? 24.91690 -8.61628  17.53285  1.000 38.17929  ? 121 ILE   A CD1  1 
ATOM   2128 H  H    . ILE   A 1 121 ? 29.12787 -9.42378  15.84725  1.000 34.73553  ? 121 ILE   A H    1 
ATOM   2129 H  HA   . ILE   A 1 121 ? 26.99996 -10.04520 14.25963  1.000 34.08155  ? 121 ILE   A HA   1 
ATOM   2130 H  HB   . ILE   A 1 121 ? 27.06839 -7.78503  15.94775  1.000 39.33958  ? 121 ILE   A HB   1 
ATOM   2131 H  HG12 . ILE   A 1 121 ? 25.42191 -10.07868 16.19235  1.000 39.30121  ? 121 ILE   A HG12 1 
ATOM   2132 H  HG13 . ILE   A 1 121 ? 26.60717 -9.71829  17.18768  1.000 39.30121  ? 121 ILE   A HG13 1 
ATOM   2133 H  HG21 . ILE   A 1 121 ? 24.91740 -7.33783  15.17727  1.000 43.38716  ? 121 ILE   A HG21 1 
ATOM   2134 H  HG22 . ILE   A 1 121 ? 25.96113 -7.30272  13.98023  1.000 43.38716  ? 121 ILE   A HG22 1 
ATOM   2135 H  HG23 . ILE   A 1 121 ? 25.02496 -8.57033  14.18084  1.000 43.38716  ? 121 ILE   A HG23 1 
ATOM   2136 H  HD11 . ILE   A 1 121 ? 24.67508 -9.19534  18.27252  1.000 45.82941  ? 121 ILE   A HD11 1 
ATOM   2137 H  HD12 . ILE   A 1 121 ? 25.33859 -7.80973  17.86835  1.000 45.82941  ? 121 ILE   A HD12 1 
ATOM   2138 H  HD13 . ILE   A 1 121 ? 24.12616 -8.38726  17.01984  1.000 45.82941  ? 121 ILE   A HD13 1 
ATOM   2139 N  N    . LEU   A 1 122 ? 28.13817 -8.94035  12.38635  1.000 29.71429  ? 122 LEU   A N    1 
ATOM   2140 C  CA   . LEU   A 1 122 ? 28.98297 -8.40736  11.31958  1.000 30.03520  ? 122 LEU   A CA   1 
ATOM   2141 C  C    . LEU   A 1 122 ? 28.16158 -7.90544  10.13978  1.000 32.10542  ? 122 LEU   A C    1 
ATOM   2142 O  O    . LEU   A 1 122 ? 27.25000 -8.59231  9.66423   1.000 32.29325  ? 122 LEU   A O    1 
ATOM   2143 C  CB   . LEU   A 1 122 ? 29.96012 -9.48870  10.80806  1.000 38.72429  ? 122 LEU   A CB   1 
ATOM   2144 C  CG   . LEU   A 1 122 ? 30.90738 -10.13098 11.80180  1.000 45.31004  ? 122 LEU   A CG   1 
ATOM   2145 C  CD1  . LEU   A 1 122 ? 31.53266 -11.37827 11.20467  1.000 41.59246  ? 122 LEU   A CD1  1 
ATOM   2146 C  CD2  . LEU   A 1 122 ? 31.96896 -9.13010  12.19938  1.000 43.57064  ? 122 LEU   A CD2  1 
ATOM   2147 H  H    . LEU   A 1 122 ? 27.56406 -9.52215  12.11896  1.000 35.67142  ? 122 LEU   A H    1 
ATOM   2148 H  HA   . LEU   A 1 122 ? 29.46465 -7.64800  11.68325  1.000 36.05651  ? 122 LEU   A HA   1 
ATOM   2149 H  HB2  . LEU   A 1 122 ? 29.43002 -10.20621 10.42717  1.000 46.48342  ? 122 LEU   A HB2  1 
ATOM   2150 H  HB3  . LEU   A 1 122 ? 30.51228 -9.08349  10.12117  1.000 46.48342  ? 122 LEU   A HB3  1 
ATOM   2151 H  HG   . LEU   A 1 122 ? 30.42278 -10.40012 12.59780  1.000 54.38632  ? 122 LEU   A HG   1 
ATOM   2152 H  HD11 . LEU   A 1 122 ? 32.16322 -11.75089 11.84064  1.000 49.92522  ? 122 LEU   A HD11 1 
ATOM   2153 H  HD12 . LEU   A 1 122 ? 30.83293 -12.02305 11.01614  1.000 49.92522  ? 122 LEU   A HD12 1 
ATOM   2154 H  HD13 . LEU   A 1 122 ? 31.99217 -11.13950 10.38446  1.000 49.92522  ? 122 LEU   A HD13 1 
ATOM   2155 H  HD21 . LEU   A 1 122 ? 32.34451 -9.39110  13.05480  1.000 52.29904  ? 122 LEU   A HD21 1 
ATOM   2156 H  HD22 . LEU   A 1 122 ? 32.66346 -9.12061  11.52228  1.000 52.29904  ? 122 LEU   A HD22 1 
ATOM   2157 H  HD23 . LEU   A 1 122 ? 31.56397 -8.25153  12.27016  1.000 52.29904  ? 122 LEU   A HD23 1 
ATOM   2158 N  N    . GLN   A 1 123 ? 28.49921 -6.71979  9.65084   1.000 31.77595  ? 123 GLN   A N    1 
ATOM   2159 C  CA   . GLN   A 1 123 ? 27.95937 -6.22629  8.38868   1.000 32.29854  ? 123 GLN   A CA   1 
ATOM   2160 C  C    . GLN   A 1 123 ? 28.95651 -6.55110  7.27754   1.000 43.38606  ? 123 GLN   A C    1 
ATOM   2161 O  O    . GLN   A 1 123 ? 29.68412 -5.70695  6.76249   1.000 38.37246  ? 123 GLN   A O    1 
ATOM   2162 C  CB   . GLN   A 1 123 ? 27.65976 -4.73669  8.47253   1.000 38.52577  ? 123 GLN   A CB   1 
ATOM   2163 C  CG   . GLN   A 1 123 ? 26.39563 -4.41084  9.25243   1.000 56.60873  ? 123 GLN   A CG   1 
ATOM   2164 C  CD   . GLN   A 1 123 ? 25.56364 -3.32501  8.58938   1.000 67.95372  ? 123 GLN   A CD   1 
ATOM   2165 O  OE1  . GLN   A 1 123 ? 24.42384 -3.55894  8.19580   1.000 47.15411  ? 123 GLN   A OE1  1 
ATOM   2166 N  NE2  . GLN   A 1 123 ? 26.13052 -2.13337  8.46825   1.000 60.12313  ? 123 GLN   A NE2  1 
ATOM   2167 H  H    . GLN   A 1 123 ? 29.04437 -6.17611  10.03400  1.000 38.14541  ? 123 GLN   A H    1 
ATOM   2168 H  HA   . GLN   A 1 123 ? 27.12037 -6.67500  8.19988   1.000 38.77252  ? 123 GLN   A HA   1 
ATOM   2169 H  HB2  . GLN   A 1 123 ? 28.40199 -4.29335  8.91234   1.000 46.24519  ? 123 GLN   A HB2  1 
ATOM   2170 H  HB3  . GLN   A 1 123 ? 27.55130 -4.38909  7.57346   1.000 46.24519  ? 123 GLN   A HB3  1 
ATOM   2171 H  HG2  . GLN   A 1 123 ? 25.84950 -5.20976  9.31851   1.000 67.94475  ? 123 GLN   A HG2  1 
ATOM   2172 H  HG3  . GLN   A 1 123 ? 26.64098 -4.10244  10.13876  1.000 67.94475  ? 123 GLN   A HG3  1 
ATOM   2173 H  HE21 . GLN   A 1 123 ? 26.93010 -2.00610  8.75820   1.000 72.16203  ? 123 GLN   A HE21 1 
ATOM   2174 H  HE22 . GLN   A 1 123 ? 25.69883 -1.48730  8.09970   1.000 72.16203  ? 123 GLN   A HE22 1 
ATOM   2175 N  N    A ARG   A 1 124 ? 28.98919 -7.83393  6.95260   0.530 37.05009  ? 124 ARG   A N    1 
ATOM   2176 N  N    B ARG   A 1 124 ? 28.98543 -7.83048  6.91514   0.470 37.05795  ? 124 ARG   A N    1 
ATOM   2177 C  CA   A ARG   A 1 124 ? 29.84266 -8.36481  5.91234   0.530 33.75127  ? 124 ARG   A CA   1 
ATOM   2178 C  CA   B ARG   A 1 124 ? 29.90688 -8.33558  5.90685   0.470 33.96684  ? 124 ARG   A CA   1 
ATOM   2179 C  C    A ARG   A 1 124 ? 29.06234 -9.44090  5.18373   0.530 34.15023  ? 124 ARG   A C    1 
ATOM   2180 C  C    B ARG   A 1 124 ? 29.31202 -9.59898  5.30965   0.470 31.31120  ? 124 ARG   A C    1 
ATOM   2181 O  O    A ARG   A 1 124 ? 28.01033 -9.89500  5.64224   0.530 30.75340  ? 124 ARG   A O    1 
ATOM   2182 O  O    B ARG   A 1 124 ? 28.63832 -10.35608 6.00332   0.470 27.38618  ? 124 ARG   A O    1 
ATOM   2183 C  CB   A ARG   A 1 124 ? 31.13991 -8.93387  6.48563   0.530 39.13770  ? 124 ARG   A CB   1 
ATOM   2184 C  CB   B ARG   A 1 124 ? 31.28337 -8.64086  6.50428   0.470 40.20526  ? 124 ARG   A CB   1 
ATOM   2185 C  CG   A ARG   A 1 124 ? 31.99656 -7.91870  7.21496   0.530 32.15782  ? 124 ARG   A CG   1 
ATOM   2186 C  CG   B ARG   A 1 124 ? 32.41353 -7.67733  6.13694   0.470 50.39436  ? 124 ARG   A CG   1 
ATOM   2187 C  CD   A ARG   A 1 124 ? 32.58471 -6.89573  6.25246   0.530 46.28644  ? 124 ARG   A CD   1 
ATOM   2188 C  CD   B ARG   A 1 124 ? 33.70096 -8.15425  6.81718   0.470 64.95374  ? 124 ARG   A CD   1 
ATOM   2189 N  NE   A ARG   A 1 124 ? 33.62928 -6.09744  6.88110   0.530 50.23626  ? 124 ARG   A NE   1 
ATOM   2190 N  NE   B ARG   A 1 124 ? 34.80552 -7.20706  6.75375   0.470 48.23750  ? 124 ARG   A NE   1 
ATOM   2191 C  CZ   A ARG   A 1 124 ? 33.40900 -5.00836  7.60432   0.530 46.78413  ? 124 ARG   A CZ   1 
ATOM   2192 C  CZ   B ARG   A 1 124 ? 36.04648 -7.51835  6.39583   0.470 28.36390  ? 124 ARG   A CZ   1 
ATOM   2193 N  NH1  A ARG   A 1 124 ? 32.18325 -4.56271  7.82629   0.530 41.22218  ? 124 ARG   A NH1  1 
ATOM   2194 N  NH1  B ARG   A 1 124 ? 36.36790 -8.73788  5.98976   0.470 57.66367  ? 124 ARG   A NH1  1 
ATOM   2195 N  NH2  A ARG   A 1 124 ? 34.44495 -4.35166  8.11688   0.530 46.59904  ? 124 ARG   A NH2  1 
ATOM   2196 N  NH2  B ARG   A 1 124 ? 36.98889 -6.58896  6.46580   0.470 40.43290  ? 124 ARG   A NH2  1 
ATOM   2197 H  H    A ARG   A 1 124 ? 28.50809 -8.43511  7.33565   0.530 44.47438  ? 124 ARG   A H    1 
ATOM   2198 H  H    B ARG   A 1 124 ? 28.47153 -8.43589  7.24525   0.470 44.48381  ? 124 ARG   A H    1 
ATOM   2199 H  HA   A ARG   A 1 124 ? 30.08056 -7.66375  5.28558   0.530 40.51579  ? 124 ARG   A HA   1 
ATOM   2200 H  HA   B ARG   A 1 124 ? 30.01700 -7.67381  5.20625   0.470 40.77448  ? 124 ARG   A HA   1 
ATOM   2201 H  HB2  A ARG   A 1 124 ? 30.91795 -9.63766  7.11516   0.530 46.97952  ? 124 ARG   A HB2  1 
ATOM   2202 H  HB2  B ARG   A 1 124 ? 31.20189 -8.62892  7.47077   0.470 48.26059  ? 124 ARG   A HB2  1 
ATOM   2203 H  HB3  A ARG   A 1 124 ? 31.66844 -9.29515  5.75691   0.530 46.97952  ? 124 ARG   A HB3  1 
ATOM   2204 H  HB3  B ARG   A 1 124 ? 31.55294 -9.52326  6.20494   0.470 48.26059  ? 124 ARG   A HB3  1 
ATOM   2205 H  HG2  A ARG   A 1 124 ? 31.45351 -7.44812  7.86652   0.530 38.60366  ? 124 ARG   A HG2  1 
ATOM   2206 H  HG2  B ARG   A 1 124 ? 32.54603 -7.67116  5.17606   0.470 60.48750  ? 124 ARG   A HG2  1 
ATOM   2207 H  HG3  A ARG   A 1 124 ? 32.72773 -8.37501  7.66002   0.530 38.60366  ? 124 ARG   A HG3  1 
ATOM   2208 H  HG3  B ARG   A 1 124 ? 32.20263 -6.78327  6.44851   0.470 60.48750  ? 124 ARG   A HG3  1 
ATOM   2209 H  HD2  A ARG   A 1 124 ? 32.97162 -7.35751  5.49222   0.530 55.55800  ? 124 ARG   A HD2  1 
ATOM   2210 H  HD2  B ARG   A 1 124 ? 33.51246 -8.32082  7.75399   0.470 77.95876  ? 124 ARG   A HD2  1 
ATOM   2211 H  HD3  A ARG   A 1 124 ? 31.88258 -6.29648  5.95444   0.530 55.55800  ? 124 ARG   A HD3  1 
ATOM   2212 H  HD3  B ARG   A 1 124 ? 33.99320 -8.97299  6.38689   0.470 77.95876  ? 124 ARG   A HD3  1 
ATOM   2213 H  HE   A ARG   A 1 124 ? 34.44454 -6.35013  6.77573   0.530 60.29779  ? 124 ARG   A HE   1 
ATOM   2214 H  HE   B ARG   A 1 124 ? 34.64301 -6.38880  6.96266   0.470 57.89927  ? 124 ARG   A HE   1 
ATOM   2215 H  HH11 A ARG   A 1 124 ? 31.50747 -4.98165  7.49854   0.530 49.48089  ? 124 ARG   A HH11 1 
ATOM   2216 H  HH11 B ARG   A 1 124 ? 35.76631 -9.35134  5.95295   0.470 69.21068  ? 124 ARG   A HH11 1 
ATOM   2217 H  HH12 A ARG   A 1 124 ? 32.06224 -3.85409  8.29831   0.530 49.48089  ? 124 ARG   A HH12 1 
ATOM   2218 H  HH12 B ARG   A 1 124 ? 37.17811 -8.91600  5.76298   0.470 69.21068  ? 124 ARG   A HH12 1 
ATOM   2219 H  HH21 A ARG   A 1 124 ? 35.24503 -4.63463  7.97757   0.530 55.93312  ? 124 ARG   A HH21 1 
ATOM   2220 H  HH21 B ARG   A 1 124 ? 36.79298 -5.79770  6.73987   0.470 48.53376  ? 124 ARG   A HH21 1 
ATOM   2221 H  HH22 A ARG   A 1 124 ? 34.31507 -3.64386  8.58777   0.530 55.93312  ? 124 ARG   A HH22 1 
ATOM   2222 H  HH22 B ARG   A 1 124 ? 37.79628 -6.77720  6.23712   0.470 48.53376  ? 124 ARG   A HH22 1 
ATOM   2223 N  N    . ASP   A 1 125 ? 29.56974 -9.82319  4.01774   1.000 31.88248  ? 125 ASP   A N    1 
ATOM   2224 C  CA   . ASP   A 1 125 ? 29.09465 -11.04203 3.38131   1.000 34.53178  ? 125 ASP   A CA   1 
ATOM   2225 C  C    . ASP   A 1 125 ? 29.61916 -12.23845 4.17171   1.000 35.55022  ? 125 ASP   A C    1 
ATOM   2226 O  O    . ASP   A 1 125 ? 30.78409 -12.27391 4.57671   1.000 31.28882  ? 125 ASP   A O    1 
ATOM   2227 C  CB   . ASP   A 1 125 ? 29.54322 -11.10938 1.92501   1.000 33.34541  ? 125 ASP   A CB   1 
ATOM   2228 C  CG   . ASP   A 1 125 ? 28.92888 -10.01598 1.07381   1.000 32.90200  ? 125 ASP   A CG   1 
ATOM   2229 O  OD1  . ASP   A 1 125 ? 27.93670 -9.36724  1.50645   1.000 28.97668  ? 125 ASP   A OD1  1 
ATOM   2230 O  OD2  . ASP   A 1 125 ? 29.42292 -9.80753  -0.03827  1.000 32.61892  ? 125 ASP   A OD2  1 
ATOM   2231 H  H    A ASP   A 1 125 ? 30.17964 -9.40116  3.58240   0.530 38.27325  ? 125 ASP   A H    1 
ATOM   2232 H  H    B ASP   A 1 125 ? 30.00906 -9.29311  3.50235   0.470 38.27325  ? 125 ASP   A H    1 
ATOM   2233 H  HA   . ASP   A 1 125 ? 28.12496 -11.06403 3.37059   1.000 41.45241  ? 125 ASP   A HA   1 
ATOM   2234 H  HB2  . ASP   A 1 125 ? 30.50774 -11.01409 1.88619   1.000 40.02876  ? 125 ASP   A HB2  1 
ATOM   2235 H  HB3  . ASP   A 1 125 ? 29.27907 -11.96482 1.55171   1.000 40.02876  ? 125 ASP   A HB3  1 
ATOM   2236 N  N    . THR   A 1 126 ? 28.75280 -13.23187 4.37766   1.000 31.20506  ? 126 THR   A N    1 
ATOM   2237 C  CA   . THR   A 1 126 ? 29.04120 -14.28422 5.34580   1.000 30.74169  ? 126 THR   A CA   1 
ATOM   2238 C  C    . THR   A 1 126 ? 30.27594 -15.09677 4.97059   1.000 26.28987  ? 126 THR   A C    1 
ATOM   2239 O  O    . THR   A 1 126 ? 31.06973 -15.47680 5.83314   1.000 29.76515  ? 126 THR   A O    1 
ATOM   2240 C  CB   . THR   A 1 126 ? 27.82410 -15.21074 5.47282   1.000 29.79557  ? 126 THR   A CB   1 
ATOM   2241 O  OG1  . THR   A 1 126 ? 26.66426 -14.42575 5.77181   1.000 30.60119  ? 126 THR   A OG1  1 
ATOM   2242 C  CG2  . THR   A 1 126 ? 28.04682 -16.23566 6.57696   1.000 40.30165  ? 126 THR   A CG2  1 
ATOM   2243 H  H    . THR   A 1 126 ? 27.99875 -13.31769 3.97313   1.000 37.46034  ? 126 THR   A H    1 
ATOM   2244 H  HA   . THR   A 1 126 ? 29.21725 -13.86617 6.20321   1.000 36.90430  ? 126 THR   A HA   1 
ATOM   2245 H  HB   . THR   A 1 126 ? 27.68609 -15.68969 4.64068   1.000 35.76895  ? 126 THR   A HB   1 
ATOM   2246 H  HG1  . THR   A 1 126 ? 25.99107 -14.92317 5.84245   1.000 36.73569  ? 126 THR   A HG1  1 
ATOM   2247 H  HG21 . THR   A 1 126 ? 27.22592 -16.72353 6.74726   1.000 48.37626  ? 126 THR   A HG21 1 
ATOM   2248 H  HG22 . THR   A 1 126 ? 28.73712 -16.86365 6.31236   1.000 48.37626  ? 126 THR   A HG22 1 
ATOM   2249 H  HG23 . THR   A 1 126 ? 28.32298 -15.78964 7.39286   1.000 48.37626  ? 126 THR   A HG23 1 
ATOM   2250 N  N    . GLU   A 1 127 ? 30.45343 -15.39376 3.68698   1.000 27.39180  ? 127 GLU   A N    1 
ATOM   2251 C  CA   . GLU   A 1 127 ? 31.53788 -16.30027 3.30570   1.000 27.55784  ? 127 GLU   A CA   1 
ATOM   2252 C  C    . GLU   A 1 127 ? 32.90017 -15.66739 3.53406   1.000 26.54551  ? 127 GLU   A C    1 
ATOM   2253 O  O    . GLU   A 1 127 ? 33.74299 -16.28669 4.20208   1.000 29.17100  ? 127 GLU   A O    1 
ATOM   2254 C  CB   . GLU   A 1 127 ? 31.35867 -16.73105 1.84153   1.000 36.89333  ? 127 GLU   A CB   1 
ATOM   2255 C  CG   . GLU   A 1 127 ? 32.39700 -17.72271 1.37101   1.000 37.94385  ? 127 GLU   A CG   1 
ATOM   2256 C  CD   . GLU   A 1 127 ? 32.21501 -18.07566 -0.09566  1.000 51.56918  ? 127 GLU   A CD   1 
ATOM   2257 O  OE1  . GLU   A 1 127 ? 32.68822 -17.29948 -0.95312  1.000 56.49071  ? 127 GLU   A OE1  1 
ATOM   2258 O  OE2  . GLU   A 1 127 ? 31.57330 -19.10706 -0.36989  1.000 50.77384  ? 127 GLU   A OE2  1 
ATOM   2259 H  H    . GLU   A 1 127 ? 29.97770 -15.09573 3.03547   1.000 32.88443  ? 127 GLU   A H    1 
ATOM   2260 H  HA   . GLU   A 1 127 ? 31.47205 -17.08838 3.86735   1.000 33.08368  ? 127 GLU   A HA   1 
ATOM   2261 H  HB2  . GLU   A 1 127 ? 30.48687 -17.14453 1.74205   1.000 44.28627  ? 127 GLU   A HB2  1 
ATOM   2262 H  HB3  . GLU   A 1 127 ? 31.42004 -15.94593 1.27520   1.000 44.28627  ? 127 GLU   A HB3  1 
ATOM   2263 H  HG2  . GLU   A 1 127 ? 33.28054 -17.33867 1.48405   1.000 45.54689  ? 127 GLU   A HG2  1 
ATOM   2264 H  HG3  . GLU   A 1 127 ? 32.32031 -18.53750 1.89170   1.000 45.54689  ? 127 GLU   A HG3  1 
ATOM   2265 N  N    . PRO   A 1 128 ? 33.21456 -14.48997 2.97209   1.000 33.07174  ? 128 PRO   A N    1 
ATOM   2266 C  CA   . PRO   A 1 128 ? 34.53510 -13.89780 3.25364   1.000 31.56664  ? 128 PRO   A CA   1 
ATOM   2267 C  C    . PRO   A 1 128 ? 34.71536 -13.53107 4.71889   1.000 29.48050  ? 128 PRO   A C    1 
ATOM   2268 O  O    . PRO   A 1 128 ? 35.81479 -13.67128 5.25471   1.000 32.02539  ? 128 PRO   A O    1 
ATOM   2269 C  CB   . PRO   A 1 128 ? 34.55715 -12.65337 2.35515   1.000 31.73708  ? 128 PRO   A CB   1 
ATOM   2270 C  CG   . PRO   A 1 128 ? 33.12800 -12.30179 2.20034   1.000 28.80059  ? 128 PRO   A CG   1 
ATOM   2271 C  CD   . PRO   A 1 128 ? 32.42302 -13.62912 2.07722   1.000 31.41778  ? 128 PRO   A CD   1 
ATOM   2272 H  HA   . PRO   A 1 128 ? 35.23786 -14.50714 2.97847   1.000 37.89424  ? 128 PRO   A HA   1 
ATOM   2273 H  HB2  . PRO   A 1 128 ? 35.05009 -11.93790 2.78644   1.000 38.09877  ? 128 PRO   A HB2  1 
ATOM   2274 H  HB3  . PRO   A 1 128 ? 34.96128 -12.86568 1.49928   1.000 38.09877  ? 128 PRO   A HB3  1 
ATOM   2275 H  HG2  . PRO   A 1 128 ? 32.81916 -11.81429 2.98000   1.000 34.57498  ? 128 PRO   A HG2  1 
ATOM   2276 H  HG3  . PRO   A 1 128 ? 33.00216 -11.76513 1.40218   1.000 34.57498  ? 128 PRO   A HG3  1 
ATOM   2277 H  HD2  . PRO   A 1 128 ? 31.50324 -13.56489 2.37851   1.000 37.71561  ? 128 PRO   A HD2  1 
ATOM   2278 H  HD3  . PRO   A 1 128 ? 32.45103 -13.95565 1.16426   1.000 37.71561  ? 128 PRO   A HD3  1 
ATOM   2279 N  N    . ALA   A 1 129 ? 33.66451 -13.03400 5.36581   1.000 31.15565  ? 129 ALA   A N    1 
ATOM   2280 C  CA   . ALA   A 1 129 ? 33.73864 -12.71792 6.78979   1.000 31.53270  ? 129 ALA   A CA   1 
ATOM   2281 C  C    . ALA   A 1 129 ? 34.16490 -13.92926 7.60489   1.000 29.33637  ? 129 ALA   A C    1 
ATOM   2282 O  O    . ALA   A 1 129 ? 35.06470 -13.84238 8.44412   1.000 29.81299  ? 129 ALA   A O    1 
ATOM   2283 C  CB   . ALA   A 1 129 ? 32.38303 -12.18677 7.26078   1.000 29.27824  ? 129 ALA   A CB   1 
ATOM   2284 H  H    . ALA   A 1 129 ? 32.90043 -12.87085 5.00642   1.000 37.40105  ? 129 ALA   A H    1 
ATOM   2285 H  HA   . ALA   A 1 129 ? 34.40426 -12.02634 6.92971   1.000 37.85351  ? 129 ALA   A HA   1 
ATOM   2286 H  HB1  . ALA   A 1 129 ? 32.47893 -11.82611 8.15612   1.000 35.14816  ? 129 ALA   A HB1  1 
ATOM   2287 H  HB2  . ALA   A 1 129 ? 32.08844 -11.49021 6.65339   1.000 35.14816  ? 129 ALA   A HB2  1 
ATOM   2288 H  HB3  . ALA   A 1 129 ? 31.74243 -12.91513 7.26443   1.000 35.14816  ? 129 ALA   A HB3  1 
ATOM   2289 N  N    . THR   A 1 130 ? 33.51950 -15.07450 7.37762   1.000 27.87136  ? 130 THR   A N    1 
ATOM   2290 C  CA   . THR   A 1 130 ? 33.85178 -16.27767 8.12993   1.000 28.41083  ? 130 THR   A CA   1 
ATOM   2291 C  C    . THR   A 1 130 ? 35.25312 -16.77276 7.78684   1.000 31.15210  ? 130 THR   A C    1 
ATOM   2292 O  O    . THR   A 1 130 ? 35.97829 -17.24620 8.66479   1.000 32.81493  ? 130 THR   A O    1 
ATOM   2293 C  CB   . THR   A 1 130 ? 32.80931 -17.36146 7.85501   1.000 36.08262  ? 130 THR   A CB   1 
ATOM   2294 O  OG1  . THR   A 1 130 ? 31.49911 -16.83568 8.09589   1.000 34.31749  ? 130 THR   A OG1  1 
ATOM   2295 C  CG2  . THR   A 1 130 ? 33.03702 -18.56205 8.74489   1.000 41.39661  ? 130 THR   A CG2  1 
ATOM   2296 H  H    . THR   A 1 130 ? 32.89195 -15.17837 6.79884   1.000 33.45990  ? 130 THR   A H    1 
ATOM   2297 H  HA   . THR   A 1 130 ? 33.83309 -16.07575 9.07850   1.000 34.10727  ? 130 THR   A HA   1 
ATOM   2298 H  HB   . THR   A 1 130 ? 32.88057 -17.65006 6.93168   1.000 43.31341  ? 130 THR   A HB   1 
ATOM   2299 H  HG1  . THR   A 1 130 ? 31.35124 -16.18678 7.58338   1.000 41.19527  ? 130 THR   A HG1  1 
ATOM   2300 H  HG21 . THR   A 1 130 ? 32.33362 -19.21554 8.60679   1.000 49.69020  ? 130 THR   A HG21 1 
ATOM   2301 H  HG22 . THR   A 1 130 ? 33.89183 -18.97111 8.53785   1.000 49.69020  ? 130 THR   A HG22 1 
ATOM   2302 H  HG23 . THR   A 1 130 ? 33.03553 -18.28995 9.67595   1.000 49.69020  ? 130 THR   A HG23 1 
ATOM   2303 N  N    . ALA   A 1 131 ? 35.65515 -16.67116 6.51928   1.000 31.81669  ? 131 ALA   A N    1 
ATOM   2304 C  CA   . ALA   A 1 131 ? 37.02193 -17.04994 6.15512   1.000 32.25637  ? 131 ALA   A CA   1 
ATOM   2305 C  C    . ALA   A 1 131 ? 38.03529 -16.14620 6.84398   1.000 27.15789  ? 131 ALA   A C    1 
ATOM   2306 O  O    . ALA   A 1 131 ? 39.10139 -16.60422 7.27628   1.000 35.45460  ? 131 ALA   A O    1 
ATOM   2307 C  CB   . ALA   A 1 131 ? 37.19471 -16.98646 4.63638   1.000 33.36811  ? 131 ALA   A CB   1 
ATOM   2308 H  H    . ALA   A 1 131 ? 35.16951 -16.39296 5.86632   1.000 38.19430  ? 131 ALA   A H    1 
ATOM   2309 H  HA   . ALA   A 1 131 ? 37.18440 -17.96337 6.43821   1.000 38.72191  ? 131 ALA   A HA   1 
ATOM   2310 H  HB1  . ALA   A 1 131 ? 38.10156 -17.24633 4.41057   1.000 40.05601  ? 131 ALA   A HB1  1 
ATOM   2311 H  HB2  . ALA   A 1 131 ? 36.56325 -17.59444 4.22102   1.000 40.05601  ? 131 ALA   A HB2  1 
ATOM   2312 H  HB3  . ALA   A 1 131 ? 37.02631 -16.07931 4.33702   1.000 40.05601  ? 131 ALA   A HB3  1 
ATOM   2313 N  N    . PHE   A 1 132 ? 37.71708 -14.85489 6.96219   1.000 29.00256  ? 132 PHE   A N    1 
ATOM   2314 C  CA   . PHE   A 1 132 ? 38.61558 -13.92235 7.63560   1.000 26.13320  ? 132 PHE   A CA   1 
ATOM   2315 C  C    . PHE   A 1 132 ? 38.72427 -14.26089 9.12288   1.000 33.94142  ? 132 PHE   A C    1 
ATOM   2316 O  O    . PHE   A 1 132 ? 39.82367 -14.30279 9.68384   1.000 32.76175  ? 132 PHE   A O    1 
ATOM   2317 C  CB   . PHE   A 1 132 ? 38.11008 -12.49283 7.41731   1.000 27.37990  ? 132 PHE   A CB   1 
ATOM   2318 C  CG   . PHE   A 1 132 ? 39.08800 -11.41141 7.81988   1.000 30.46811  ? 132 PHE   A CG   1 
ATOM   2319 C  CD1  . PHE   A 1 132 ? 40.38499 -11.70458 8.17686   1.000 39.68172  ? 132 PHE   A CD1  1 
ATOM   2320 C  CD2  . PHE   A 1 132 ? 38.68189 -10.09355 7.85225   1.000 41.21796  ? 132 PHE   A CD2  1 
ATOM   2321 C  CE1  . PHE   A 1 132 ? 41.25369 -10.70644 8.56100   1.000 36.76123  ? 132 PHE   A CE1  1 
ATOM   2322 C  CE2  . PHE   A 1 132 ? 39.54933 -9.09354  8.22943   1.000 48.26252  ? 132 PHE   A CE2  1 
ATOM   2323 C  CZ   . PHE   A 1 132 ? 40.83379 -9.40214  8.58286   1.000 36.80120  ? 132 PHE   A CZ   1 
ATOM   2324 H  H    . PHE   A 1 132 ? 36.99362 -14.49850 6.66353   1.000 34.81735  ? 132 PHE   A H    1 
ATOM   2325 H  HA   . PHE   A 1 132 ? 39.50645 -13.98407 7.25685   1.000 31.37411  ? 132 PHE   A HA   1 
ATOM   2326 H  HB2  . PHE   A 1 132 ? 37.91530 -12.37487 6.47442   1.000 32.87016  ? 132 PHE   A HB2  1 
ATOM   2327 H  HB3  . PHE   A 1 132 ? 37.30327 -12.36736 7.94097   1.000 32.87016  ? 132 PHE   A HB3  1 
ATOM   2328 H  HD1  . PHE   A 1 132 ? 40.67827 -12.58694 8.15850   1.000 47.63234  ? 132 PHE   A HD1  1 
ATOM   2329 H  HD2  . PHE   A 1 132 ? 37.80884 -9.87741  7.61567   1.000 49.47582  ? 132 PHE   A HD2  1 
ATOM   2330 H  HE1  . PHE   A 1 132 ? 42.12564 -10.91804 8.80563   1.000 44.12775  ? 132 PHE   A HE1  1 
ATOM   2331 H  HE2  . PHE   A 1 132 ? 39.26220 -8.20909  8.24389   1.000 57.92929  ? 132 PHE   A HE2  1 
ATOM   2332 H  HZ   . PHE   A 1 132 ? 41.42148 -8.72790  8.83766   1.000 44.17571  ? 132 PHE   A HZ   1 
ATOM   2333 N  N    . LEU   A 1 133 ? 37.59139 -14.51947 9.77244   1.000 28.85793  ? 133 LEU   A N    1 
ATOM   2334 C  CA   . LEU   A 1 133 ? 37.60767 -14.92711 11.17440  1.000 27.81878  ? 133 LEU   A CA   1 
ATOM   2335 C  C    . LEU   A 1 133 ? 38.42830 -16.19930 11.36060  1.000 32.42910  ? 133 LEU   A C    1 
ATOM   2336 O  O    . LEU   A 1 133 ? 39.11423 -16.36513 12.37438  1.000 33.45439  ? 133 LEU   A O    1 
ATOM   2337 C  CB   . LEU   A 1 133 ? 36.17926 -15.15728 11.66968  1.000 34.53499  ? 133 LEU   A CB   1 
ATOM   2338 C  CG   . LEU   A 1 133 ? 35.31361 -13.93192 11.89672  1.000 33.54881  ? 133 LEU   A CG   1 
ATOM   2339 C  CD1  . LEU   A 1 133 ? 33.89010 -14.35361 12.30728  1.000 34.34678  ? 133 LEU   A CD1  1 
ATOM   2340 C  CD2  . LEU   A 1 133 ? 35.92014 -13.01069 12.94318  1.000 38.69234  ? 133 LEU   A CD2  1 
ATOM   2341 H  H    . LEU   A 1 133 ? 36.80532 -14.46700 9.42757   1.000 34.64379  ? 133 LEU   A H    1 
ATOM   2342 H  HA   . LEU   A 1 133 ? 38.00610 -14.21691 11.70144  1.000 33.39681  ? 133 LEU   A HA   1 
ATOM   2343 H  HB2  . LEU   A 1 133 ? 35.72241 -15.70675 11.01373  1.000 41.45626  ? 133 LEU   A HB2  1 
ATOM   2344 H  HB3  . LEU   A 1 133 ? 36.23075 -15.62621 12.51723  1.000 41.45626  ? 133 LEU   A HB3  1 
ATOM   2345 H  HG   . LEU   A 1 133 ? 35.26084 -13.43251 11.06683  1.000 40.27284  ? 133 LEU   A HG   1 
ATOM   2346 H  HD11 . LEU   A 1 133 ? 33.34913 -13.55838 12.43326  1.000 41.23041  ? 133 LEU   A HD11 1 
ATOM   2347 H  HD12 . LEU   A 1 133 ? 33.50940 -14.90495 11.60587  1.000 41.23041  ? 133 LEU   A HD12 1 
ATOM   2348 H  HD13 . LEU   A 1 133 ? 33.93625 -14.85685 13.13524  1.000 41.23041  ? 133 LEU   A HD13 1 
ATOM   2349 H  HD21 . LEU   A 1 133 ? 35.29113 -12.29901 13.14007  1.000 46.44508  ? 133 LEU   A HD21 1 
ATOM   2350 H  HD22 . LEU   A 1 133 ? 36.10272 -13.52246 13.74671  1.000 46.44508  ? 133 LEU   A HD22 1 
ATOM   2351 H  HD23 . LEU   A 1 133 ? 36.74451 -12.63655 12.59484  1.000 46.44508  ? 133 LEU   A HD23 1 
ATOM   2352 N  N    . ASP   A 1 134 ? 38.33874 -17.12167 10.40634  1.000 32.43900  ? 134 ASP   A N    1 
ATOM   2353 C  CA   . ASP   A 1 134 ? 39.13848 -18.34059 10.46055  1.000 31.82923  ? 134 ASP   A CA   1 
ATOM   2354 C  C    . ASP   A 1 134 ? 40.62631 -18.02622 10.38008  1.000 46.07294  ? 134 ASP   A C    1 
ATOM   2355 O  O    . ASP   A 1 134 ? 41.42978 -18.57136 11.15056  1.000 38.05912  ? 134 ASP   A O    1 
ATOM   2356 C  CB   . ASP   A 1 134 ? 38.72938 -19.27922 9.32140   1.000 40.32946  ? 134 ASP   A CB   1 
ATOM   2357 C  CG   . ASP   A 1 134 ? 38.87848 -20.74899 9.69021   1.000 71.85291  ? 134 ASP   A CG   1 
ATOM   2358 O  OD1  . ASP   A 1 134 ? 39.05027 -21.06530 10.89100  1.000 68.78139  ? 134 ASP   A OD1  1 
ATOM   2359 O  OD2  . ASP   A 1 134 ? 38.82478 -21.59074 8.77136   1.000 64.15897  ? 134 ASP   A OD2  1 
ATOM   2360 H  H    . ASP   A 1 134 ? 37.82464 -17.06661 9.71912   1.000 38.94107  ? 134 ASP   A H    1 
ATOM   2361 H  HA   . ASP   A 1 134 ? 38.96961 -18.78827 11.30433  1.000 38.20935  ? 134 ASP   A HA   1 
ATOM   2362 H  HB2  . ASP   A 1 134 ? 37.79934 -19.11859 9.09751   1.000 48.40962  ? 134 ASP   A HB2  1 
ATOM   2363 H  HB3  . ASP   A 1 134 ? 39.29121 -19.10458 8.55020   1.000 48.40962  ? 134 ASP   A HB3  1 
ATOM   2364 N  N    . ALA   A 1 135 ? 41.01325 -17.14972 9.44209   1.000 39.47534  ? 135 ALA   A N    1 
ATOM   2365 C  CA   . ALA   A 1 135 ? 42.41758 -16.77336 9.31692   1.000 39.50177  ? 135 ALA   A CA   1 
ATOM   2366 C  C    . ALA   A 1 135 ? 42.92677 -16.07346 10.56684  1.000 32.61583  ? 135 ALA   A C    1 
ATOM   2367 O  O    . ALA   A 1 135 ? 44.09306 -16.23048 10.94225  1.000 43.07292  ? 135 ALA   A O    1 
ATOM   2368 C  CB   . ALA   A 1 135 ? 42.60925 -15.87548 8.09730   1.000 35.52685  ? 135 ALA   A CB   1 
ATOM   2369 H  H    . ALA   A 1 135 ? 40.48827 -16.76789 8.87799   1.000 47.38468  ? 135 ALA   A H    1 
ATOM   2370 H  HA   . ALA   A 1 135 ? 42.94050 -17.58082 9.19256   1.000 47.41639  ? 135 ALA   A HA   1 
ATOM   2371 H  HB1  . ALA   A 1 135 ? 43.54912 -15.64989 8.01580   1.000 42.64649  ? 135 ALA   A HB1  1 
ATOM   2372 H  HB2  . ALA   A 1 135 ? 42.31335 -16.35109 7.30538   1.000 42.64649  ? 135 ALA   A HB2  1 
ATOM   2373 H  HB3  . ALA   A 1 135 ? 42.08421 -15.06822 8.21381   1.000 42.64649  ? 135 ALA   A HB3  1 
ATOM   2374 N  N    . LEU   A 1 136 ? 42.08320 -15.26480 11.20660  1.000 30.15665  ? 136 LEU   A N    1 
ATOM   2375 C  CA   . LEU   A 1 136 ? 42.46744 -14.59754 12.44213  1.000 31.40183  ? 136 LEU   A CA   1 
ATOM   2376 C  C    . LEU   A 1 136 ? 42.55070 -15.56556 13.62008  1.000 35.08900  ? 136 LEU   A C    1 
ATOM   2377 O  O    . LEU   A 1 136 ? 43.15945 -15.22589 14.64143  1.000 38.35722  ? 136 LEU   A O    1 
ATOM   2378 C  CB   . LEU   A 1 136 ? 41.47831 -13.48263 12.76703  1.000 37.99814  ? 136 LEU   A CB   1 
ATOM   2379 C  CG   . LEU   A 1 136 ? 41.48221 -12.28164 11.82034  1.000 38.91228  ? 136 LEU   A CG   1 
ATOM   2380 C  CD1  . LEU   A 1 136 ? 40.24729 -11.41632 12.04396  1.000 34.67701  ? 136 LEU   A CD1  1 
ATOM   2381 C  CD2  . LEU   A 1 136 ? 42.74229 -11.46342 12.00365  1.000 39.31707  ? 136 LEU   A CD2  1 
ATOM   2382 H  H    . LEU   A 1 136 ? 41.28358 -15.08735 10.94445  1.000 36.20225  ? 136 LEU   A H    1 
ATOM   2383 H  HA   . LEU   A 1 136 ? 43.34228 -14.19773 12.31681  1.000 37.69647  ? 136 LEU   A HA   1 
ATOM   2384 H  HB2  . LEU   A 1 136 ? 40.58406 -13.85803 12.75008  1.000 45.61204  ? 136 LEU   A HB2  1 
ATOM   2385 H  HB3  . LEU   A 1 136 ? 41.68106 -13.14845 13.65479  1.000 45.61204  ? 136 LEU   A HB3  1 
ATOM   2386 H  HG   . LEU   A 1 136 ? 41.46189 -12.60410 10.90574  1.000 46.70900  ? 136 LEU   A HG   1 
ATOM   2387 H  HD11 . LEU   A 1 136 ? 40.26580 -10.67270 11.42140  1.000 41.62668  ? 136 LEU   A HD11 1 
ATOM   2388 H  HD12 . LEU   A 1 136 ? 39.45378 -11.95365 11.89392  1.000 41.62668  ? 136 LEU   A HD12 1 
ATOM   2389 H  HD13 . LEU   A 1 136 ? 40.25481 -11.08482 12.95552  1.000 41.62668  ? 136 LEU   A HD13 1 
ATOM   2390 H  HD21 . LEU   A 1 136 ? 42.68328 -10.66551 11.45524  1.000 47.19475  ? 136 LEU   A HD21 1 
ATOM   2391 H  HD22 . LEU   A 1 136 ? 42.82572 -11.21708 12.93814  1.000 47.19475  ? 136 LEU   A HD22 1 
ATOM   2392 H  HD23 . LEU   A 1 136 ? 43.50660 -11.99550 11.73233  1.000 47.19475  ? 136 LEU   A HD23 1 
ATOM   2393 N  N    . GLY   A 1 137 ? 41.93821 -16.74014 13.50558  1.000 38.67139  ? 137 GLY   A N    1 
ATOM   2394 C  CA   . GLY   A 1 137 ? 41.98823 -17.74536 14.55072  1.000 40.28375  ? 137 GLY   A CA   1 
ATOM   2395 C  C    . GLY   A 1 137 ? 40.93369 -17.64127 15.63047  1.000 42.70682  ? 137 GLY   A C    1 
ATOM   2396 O  O    . GLY   A 1 137 ? 41.06540 -18.31194 16.66267  1.000 39.16432  ? 137 GLY   A O    1 
ATOM   2397 H  H    . GLY   A 1 137 ? 41.47996 -16.97934 12.81827  1.000 46.41994  ? 137 GLY   A H    1 
ATOM   2398 H  HA2  . GLY   A 1 137 ? 41.89586 -18.61860 14.13863  1.000 48.35477  ? 137 GLY   A HA2  1 
ATOM   2399 H  HA3  . GLY   A 1 137 ? 42.85392 -17.69103 14.98490  1.000 48.35477  ? 137 GLY   A HA3  1 
ATOM   2400 N  N    . ILE   A 1 138 ? 39.88340 -16.84151 15.43386  1.000 34.29086  ? 138 ILE   A N    1 
ATOM   2401 C  CA   . ILE   A 1 138 ? 38.87526 -16.63366 16.47295  1.000 32.89339  ? 138 ILE   A CA   1 
ATOM   2402 C  C    . ILE   A 1 138 ? 37.51140 -17.16718 16.07756  1.000 28.78571  ? 138 ILE   A C    1 
ATOM   2403 O  O    . ILE   A 1 138 ? 36.57420 -17.08877 16.88606  1.000 34.76779  ? 138 ILE   A O    1 
ATOM   2404 C  CB   . ILE   A 1 138 ? 38.77269 -15.15531 16.86470  1.000 35.02809  ? 138 ILE   A CB   1 
ATOM   2405 C  CG1  . ILE   A 1 138 ? 38.41290 -14.29801 15.66329  1.000 32.04876  ? 138 ILE   A CG1  1 
ATOM   2406 C  CG2  . ILE   A 1 138 ? 40.08389 -14.67752 17.48751  1.000 37.85650  ? 138 ILE   A CG2  1 
ATOM   2407 C  CD1  . ILE   A 1 138 ? 38.10546 -12.84953 16.02609  1.000 30.88552  ? 138 ILE   A CD1  1 
ATOM   2408 H  H    . ILE   A 1 138 ? 39.73400 -16.40861 14.70594  1.000 41.16330  ? 138 ILE   A H    1 
ATOM   2409 H  HA   . ILE   A 1 138 ? 39.15607 -17.12757 17.25915  1.000 39.48634  ? 138 ILE   A HA   1 
ATOM   2410 H  HB   . ILE   A 1 138 ? 38.06375 -15.06807 17.52098  1.000 42.04797  ? 138 ILE   A HB   1 
ATOM   2411 H  HG12 . ILE   A 1 138 ? 39.15894 -14.29798 15.04335  1.000 38.47279  ? 138 ILE   A HG12 1 
ATOM   2412 H  HG13 . ILE   A 1 138 ? 37.62633 -14.67147 15.23581  1.000 38.47279  ? 138 ILE   A HG13 1 
ATOM   2413 H  HG21 . ILE   A 1 138 ? 39.95210 -13.79180 17.86037  1.000 45.44207  ? 138 ILE   A HG21 1 
ATOM   2414 H  HG22 . ILE   A 1 138 ? 40.34457 -15.29586 18.18794  1.000 45.44207  ? 138 ILE   A HG22 1 
ATOM   2415 H  HG23 . ILE   A 1 138 ? 40.76787 -14.64871 16.80031  1.000 45.44207  ? 138 ILE   A HG23 1 
ATOM   2416 H  HD11 . ILE   A 1 138 ? 37.77206 -12.39080 15.23913  1.000 37.07689  ? 138 ILE   A HD11 1 
ATOM   2417 H  HD12 . ILE   A 1 138 ? 37.43458 -12.83498 16.72652  1.000 37.07689  ? 138 ILE   A HD12 1 
ATOM   2418 H  HD13 . ILE   A 1 138 ? 38.91871 -12.42268 16.33808  1.000 37.07689  ? 138 ILE   A HD13 1 
ATOM   2419 N  N    . LYS   A 1 139 ? 37.36574 -17.72650 14.87402  1.000 33.24773  ? 139 LYS   A N    1 
ATOM   2420 C  CA   . LYS   A 1 139 ? 36.05118 -18.17691 14.42547  1.000 29.62264  ? 139 LYS   A CA   1 
ATOM   2421 C  C    . LYS   A 1 139 ? 35.39261 -19.09027 15.44738  1.000 35.08278  ? 139 LYS   A C    1 
ATOM   2422 O  O    . LYS   A 1 139 ? 34.23584 -18.88792 15.81641  1.000 33.16288  ? 139 LYS   A O    1 
ATOM   2423 C  CB   . LYS   A 1 139 ? 36.15840 -18.88752 13.08158  1.000 32.57338  ? 139 LYS   A CB   1 
ATOM   2424 C  CG   . LYS   A 1 139 ? 34.85481 -19.48091 12.59439  1.000 37.67949  ? 139 LYS   A CG   1 
ATOM   2425 C  CD   . LYS   A 1 139 ? 35.03517 -20.12611 11.23413  1.000 50.86988  ? 139 LYS   A CD   1 
ATOM   2426 C  CE   . LYS   A 1 139 ? 34.35601 -21.48010 11.15364  1.000 73.61205  ? 139 LYS   A CE   1 
ATOM   2427 N  NZ   . LYS   A 1 139 ? 34.17731 -21.90513 9.73022   1.000 92.17715  ? 139 LYS   A NZ   1 
ATOM   2428 H  H    . LYS   A 1 139 ? 38.00170 -17.85374 14.30925  1.000 39.91155  ? 139 LYS   A H    1 
ATOM   2429 H  HA   . LYS   A 1 139 ? 35.49136 -17.39311 14.31081  1.000 35.56144  ? 139 LYS   A HA   1 
ATOM   2430 H  HB2  . LYS   A 1 139 ? 36.45956 -18.24970 12.41571  1.000 39.10232  ? 139 LYS   A HB2  1 
ATOM   2431 H  HB3  . LYS   A 1 139 ? 36.79995 -19.61056 13.16244  1.000 39.10232  ? 139 LYS   A HB3  1 
ATOM   2432 H  HG2  . LYS   A 1 139 ? 34.55321 -20.15858 13.21946  1.000 45.22966  ? 139 LYS   A HG2  1 
ATOM   2433 H  HG3  . LYS   A 1 139 ? 34.18826 -18.78043 12.51738  1.000 45.22966  ? 139 LYS   A HG3  1 
ATOM   2434 H  HD2  . LYS   A 1 139 ? 34.64819 -19.55231 10.55451  1.000 61.05813  ? 139 LYS   A HD2  1 
ATOM   2435 H  HD3  . LYS   A 1 139 ? 35.98168 -20.25141 11.06291  1.000 61.05813  ? 139 LYS   A HD3  1 
ATOM   2436 H  HE2  . LYS   A 1 139 ? 34.90123 -22.14261 11.60609  1.000 88.34873  ? 139 LYS   A HE2  1 
ATOM   2437 H  HE3  . LYS   A 1 139 ? 33.48194 -21.42861 11.57107  1.000 88.34873  ? 139 LYS   A HE3  1 
ATOM   2438 H  HZ1  . LYS   A 1 139 ? 33.87667 -22.74219 9.69794   1.000 110.62686 ? 139 LYS   A HZ1  1 
ATOM   2439 H  HZ2  . LYS   A 1 139 ? 33.59140 -21.37195 9.32460   1.000 110.62686 ? 139 LYS   A HZ2  1 
ATOM   2440 H  HZ3  . LYS   A 1 139 ? 34.95480 -21.86065 9.29937   1.000 110.62686 ? 139 LYS   A HZ3  1 
ATOM   2441 N  N    . ASP   A 1 140 ? 36.11785 -20.10270 15.91431  1.000 36.80213  ? 140 ASP   A N    1 
ATOM   2442 C  CA   . ASP   A 1 140 ? 35.55523 -21.09535 16.82143  1.000 36.65209  ? 140 ASP   A CA   1 
ATOM   2443 C  C    . ASP   A 1 140 ? 35.50928 -20.62122 18.26726  1.000 40.18886  ? 140 ASP   A C    1 
ATOM   2444 O  O    . ASP   A 1 140 ? 35.00915 -21.35865 19.13778  1.000 32.71282  ? 140 ASP   A O    1 
ATOM   2445 C  CB   . ASP   A 1 140 ? 36.35690 -22.39732 16.71234  1.000 35.80685  ? 140 ASP   A CB   1 
ATOM   2446 C  CG   . ASP   A 1 140 ? 36.29224 -23.01038 15.31841  1.000 49.49412  ? 140 ASP   A CG   1 
ATOM   2447 O  OD1  . ASP   A 1 140 ? 35.23370 -22.90925 14.66494  1.000 47.81056  ? 140 ASP   A OD1  1 
ATOM   2448 O  OD2  . ASP   A 1 140 ? 37.30491 -23.58355 14.87314  1.000 54.16350  ? 140 ASP   A OD2  1 
ATOM   2449 H  H    . ASP   A 1 140 ? 36.94444 -20.23678 15.71844  1.000 44.17683  ? 140 ASP   A H    1 
ATOM   2450 H  HA   . ASP   A 1 140 ? 34.64163 -21.28623 16.55724  1.000 43.99678  ? 140 ASP   A HA   1 
ATOM   2451 H  HB2  . ASP   A 1 140 ? 37.28719 -22.21450 16.91739  1.000 42.98249  ? 140 ASP   A HB2  1 
ATOM   2452 H  HB3  . ASP   A 1 140 ? 35.99920 -23.04310 17.34156  1.000 42.98249  ? 140 ASP   A HB3  1 
ATOM   2453 N  N    . LEU   A 1 141 ? 36.00641 -19.41765 18.55449  1.000 30.20475  ? 141 LEU   A N    1 
ATOM   2454 C  CA   . LEU   A 1 141 ? 35.82172 -18.82670 19.87181  1.000 33.72684  ? 141 LEU   A CA   1 
ATOM   2455 C  C    . LEU   A 1 141 ? 34.42786 -18.24653 20.05340  1.000 36.99231  ? 141 LEU   A C    1 
ATOM   2456 O  O    . LEU   A 1 141 ? 34.03345 -17.94883 21.18045  1.000 38.70239  ? 141 LEU   A O    1 
ATOM   2457 C  CB   . LEU   A 1 141 ? 36.84356 -17.71329 20.12525  1.000 33.27312  ? 141 LEU   A CB   1 
ATOM   2458 C  CG   . LEU   A 1 141 ? 38.32114 -18.12914 20.14965  1.000 43.36746  ? 141 LEU   A CG   1 
ATOM   2459 C  CD1  . LEU   A 1 141 ? 39.17671 -16.94624 20.57610  1.000 40.16885  ? 141 LEU   A CD1  1 
ATOM   2460 C  CD2  . LEU   A 1 141 ? 38.55251 -19.32340 21.04946  1.000 36.84912  ? 141 LEU   A CD2  1 
ATOM   2461 H  H    . LEU   A 1 141 ? 36.45143 -18.92838 18.00479  1.000 36.25997  ? 141 LEU   A H    1 
ATOM   2462 H  HA   . LEU   A 1 141 ? 35.96776 -19.52285 20.53132  1.000 40.48648  ? 141 LEU   A HA   1 
ATOM   2463 H  HB2  . LEU   A 1 141 ? 36.74584 -17.05089 19.42340  1.000 39.94202  ? 141 LEU   A HB2  1 
ATOM   2464 H  HB3  . LEU   A 1 141 ? 36.64569 -17.31495 20.98726  1.000 39.94202  ? 141 LEU   A HB3  1 
ATOM   2465 H  HG   . LEU   A 1 141 ? 38.58783 -18.40133 19.25764  1.000 52.05522  ? 141 LEU   A HG   1 
ATOM   2466 H  HD11 . LEU   A 1 141 ? 40.10389 -17.22747 20.62230  1.000 48.21689  ? 141 LEU   A HD11 1 
ATOM   2467 H  HD12 . LEU   A 1 141 ? 39.07900 -16.23455 19.92430  1.000 48.21689  ? 141 LEU   A HD12 1 
ATOM   2468 H  HD13 . LEU   A 1 141 ? 38.88019 -16.63984 21.44736  1.000 48.21689  ? 141 LEU   A HD13 1 
ATOM   2469 H  HD21 . LEU   A 1 141 ? 39.50658 -19.48053 21.12664  1.000 44.23321  ? 141 LEU   A HD21 1 
ATOM   2470 H  HD22 . LEU   A 1 141 ? 38.17608 -19.13758 21.92392  1.000 44.23321  ? 141 LEU   A HD22 1 
ATOM   2471 H  HD23 . LEU   A 1 141 ? 38.11973 -20.09986 20.66124  1.000 44.23321  ? 141 LEU   A HD23 1 
ATOM   2472 N  N    . PHE   A 1 142 ? 33.69284 -18.04385 18.97518  1.000 29.67973  ? 142 PHE   A N    1 
ATOM   2473 C  CA   . PHE   A 1 142 ? 32.34596 -17.49240 19.05516  1.000 28.21502  ? 142 PHE   A CA   1 
ATOM   2474 C  C    . PHE   A 1 142 ? 31.33616 -18.62229 19.17763  1.000 31.11431  ? 142 PHE   A C    1 
ATOM   2475 O  O    . PHE   A 1 142 ? 31.46398 -19.65652 18.51210  1.000 30.62852  ? 142 PHE   A O    1 
ATOM   2476 C  CB   . PHE   A 1 142 ? 32.03285 -16.64608 17.81629  1.000 29.37946  ? 142 PHE   A CB   1 
ATOM   2477 C  CG   . PHE   A 1 142 ? 32.74525 -15.32525 17.79103  1.000 32.97775  ? 142 PHE   A CG   1 
ATOM   2478 C  CD1  . PHE   A 1 142 ? 32.34507 -14.29889 18.62162  1.000 29.56002  ? 142 PHE   A CD1  1 
ATOM   2479 C  CD2  . PHE   A 1 142 ? 33.82148 -15.11650 16.94156  1.000 32.96032  ? 142 PHE   A CD2  1 
ATOM   2480 C  CE1  . PHE   A 1 142 ? 33.00856 -13.07502 18.61767  1.000 31.40578  ? 142 PHE   A CE1  1 
ATOM   2481 C  CE2  . PHE   A 1 142 ? 34.48119 -13.89505 16.93530  1.000 28.89834  ? 142 PHE   A CE2  1 
ATOM   2482 C  CZ   . PHE   A 1 142 ? 34.07296 -12.87948 17.76915  1.000 32.56851  ? 142 PHE   A CZ   1 
ATOM   2483 H  H    . PHE   A 1 142 ? 33.95157 -18.21862 18.17386  1.000 35.62995  ? 142 PHE   A H    1 
ATOM   2484 H  HA   . PHE   A 1 142 ? 32.27270 -16.92141 19.83586  1.000 33.87230  ? 142 PHE   A HA   1 
ATOM   2485 H  HB2  . PHE   A 1 142 ? 32.29822 -17.14084 17.02529  1.000 35.26962  ? 142 PHE   A HB2  1 
ATOM   2486 H  HB3  . PHE   A 1 142 ? 31.07948 -16.46883 17.79240  1.000 35.26962  ? 142 PHE   A HB3  1 
ATOM   2487 H  HD1  . PHE   A 1 142 ? 31.62185 -14.42642 19.19222  1.000 35.48630  ? 142 PHE   A HD1  1 
ATOM   2488 H  HD2  . PHE   A 1 142 ? 34.10234 -15.79749 16.37387  1.000 39.56666  ? 142 PHE   A HD2  1 
ATOM   2489 H  HE1  . PHE   A 1 142 ? 32.73318 -12.39265 19.18638  1.000 37.70120  ? 142 PHE   A HE1  1 
ATOM   2490 H  HE2  . PHE   A 1 142 ? 35.20316 -13.76243 16.36428  1.000 34.69228  ? 142 PHE   A HE2  1 
ATOM   2491 H  HZ   . PHE   A 1 142 ? 34.51624 -12.06199 17.75892  1.000 39.09648  ? 142 PHE   A HZ   1 
ATOM   2492 N  N    . ASP   A 1 143 ? 30.32490 -18.41241 20.03206  1.000 29.26861  ? 143 ASP   A N    1 
ATOM   2493 C  CA   . ASP   A 1 143 ? 29.17968 -19.30949 20.05449  1.000 30.14910  ? 143 ASP   A CA   1 
ATOM   2494 C  C    . ASP   A 1 143 ? 28.22818 -19.04342 18.90242  1.000 31.93856  ? 143 ASP   A C    1 
ATOM   2495 O  O    . ASP   A 1 143 ? 27.51009 -19.95762 18.47695  1.000 30.34743  ? 143 ASP   A O    1 
ATOM   2496 C  CB   . ASP   A 1 143 ? 28.42901 -19.16516 21.37650  1.000 29.36838  ? 143 ASP   A CB   1 
ATOM   2497 C  CG   . ASP   A 1 143 ? 29.26916 -19.59135 22.56260  1.000 28.83854  ? 143 ASP   A CG   1 
ATOM   2498 O  OD1  . ASP   A 1 143 ? 29.74098 -20.73511 22.56844  1.000 35.89359  ? 143 ASP   A OD1  1 
ATOM   2499 O  OD2  . ASP   A 1 143 ? 29.49859 -18.75360 23.42589  1.000 28.11484  ? 143 ASP   A OD2  1 
ATOM   2500 H  H    . ASP   A 1 143 ? 30.28486 -17.76575 20.59759  1.000 35.13660  ? 143 ASP   A H    1 
ATOM   2501 H  HA   . ASP   A 1 143 ? 29.50017 -20.22214 19.98198  1.000 36.19319  ? 143 ASP   A HA   1 
ATOM   2502 H  HB2  . ASP   A 1 143 ? 28.17995 -18.23599 21.50102  1.000 35.25632  ? 143 ASP   A HB2  1 
ATOM   2503 H  HB3  . ASP   A 1 143 ? 27.63464 -19.72135 21.35355  1.000 35.25632  ? 143 ASP   A HB3  1 
ATOM   2504 N  N    . SER   A 1 144 ? 28.17643 -17.80704 18.39815  1.000 29.35854  ? 144 SER   A N    1 
ATOM   2505 C  CA   . SER   A 1 144 ? 27.38403 -17.51052 17.20547  1.000 28.22684  ? 144 SER   A CA   1 
ATOM   2506 C  C    . SER   A 1 144 ? 28.08208 -16.43689 16.38163  1.000 31.16336  ? 144 SER   A C    1 
ATOM   2507 O  O    . SER   A 1 144 ? 28.79905 -15.58876 16.91566  1.000 25.88996  ? 144 SER   A O    1 
ATOM   2508 C  CB   . SER   A 1 144 ? 25.96200 -17.05592 17.57957  1.000 29.16693  ? 144 SER   A CB   1 
ATOM   2509 O  OG   . SER   A 1 144 ? 25.94095 -15.77320 18.15660  1.000 29.05888  ? 144 SER   A OG   1 
ATOM   2510 H  H    . SER   A 1 144 ? 28.58935 -17.12850 18.72781  1.000 35.24452  ? 144 SER   A H    1 
ATOM   2511 H  HA   . SER   A 1 144 ? 27.32007 -18.30759 16.65640  1.000 33.88648  ? 144 SER   A HA   1 
ATOM   2512 H  HB2  . SER   A 1 144 ? 25.42036 -17.04180 16.77500  1.000 35.01459  ? 144 SER   A HB2  1 
ATOM   2513 H  HB3  . SER   A 1 144 ? 25.59322 -17.68753 18.21673  1.000 35.01459  ? 144 SER   A HB3  1 
ATOM   2514 H  HG   . SER   A 1 144 ? 25.15157 -15.55519 18.34356  1.000 34.88493  ? 144 SER   A HG   1 
ATOM   2515 N  N    . ILE   A 1 145 ? 27.88001 -16.50000 15.07155  1.000 27.41635  ? 145 ILE   A N    1 
ATOM   2516 C  CA   . ILE   A 1 145 ? 28.30676 -15.47833 14.12685  1.000 28.92515  ? 145 ILE   A CA   1 
ATOM   2517 C  C    . ILE   A 1 145 ? 27.09125 -15.12403 13.27637  1.000 30.95006  ? 145 ILE   A C    1 
ATOM   2518 O  O    . ILE   A 1 145 ? 26.49301 -16.00273 12.65187  1.000 29.85392  ? 145 ILE   A O    1 
ATOM   2519 C  CB   . ILE   A 1 145 ? 29.45573 -15.96795 13.23502  1.000 30.41195  ? 145 ILE   A CB   1 
ATOM   2520 C  CG1  . ILE   A 1 145 ? 30.68220 -16.32430 14.07306  1.000 30.42077  ? 145 ILE   A CG1  1 
ATOM   2521 C  CG2  . ILE   A 1 145 ? 29.81603 -14.90436 12.18590  1.000 31.02015  ? 145 ILE   A CG2  1 
ATOM   2522 C  CD1  . ILE   A 1 145 ? 31.69184 -17.18953 13.32733  1.000 33.91575  ? 145 ILE   A CD1  1 
ATOM   2523 H  H    . ILE   A 1 145 ? 27.47841 -17.15699 14.68857  1.000 32.91390  ? 145 ILE   A H    1 
ATOM   2524 H  HA   . ILE   A 1 145 ? 28.60539 -14.68839 14.60406  1.000 34.72446  ? 145 ILE   A HA   1 
ATOM   2525 H  HB   . ILE   A 1 145 ? 29.15636 -16.76890 12.77703  1.000 36.50861  ? 145 ILE   A HB   1 
ATOM   2526 H  HG12 . ILE   A 1 145 ? 31.12970 -15.50547 14.33796  1.000 36.51920  ? 145 ILE   A HG12 1 
ATOM   2527 H  HG13 . ILE   A 1 145 ? 30.39344 -16.81380 14.85913  1.000 36.51920  ? 145 ILE   A HG13 1 
ATOM   2528 H  HG21 . ILE   A 1 145 ? 30.64630 -15.15680 11.75252  1.000 37.23845  ? 145 ILE   A HG21 1 
ATOM   2529 H  HG22 . ILE   A 1 145 ? 29.10295 -14.85317 11.53031  1.000 37.23845  ? 145 ILE   A HG22 1 
ATOM   2530 H  HG23 . ILE   A 1 145 ? 29.92095 -14.04742 12.62811  1.000 37.23845  ? 145 ILE   A HG23 1 
ATOM   2531 H  HD11 . ILE   A 1 145 ? 32.40563 -17.43731 13.93561  1.000 40.71317  ? 145 ILE   A HD11 1 
ATOM   2532 H  HD12 . ILE   A 1 145 ? 31.24472 -17.98576 13.00020  1.000 40.71317  ? 145 ILE   A HD12 1 
ATOM   2533 H  HD13 . ILE   A 1 145 ? 32.05261 -16.68324 12.58274  1.000 40.71317  ? 145 ILE   A HD13 1 
ATOM   2534 N  N    . THR   A 1 146 ? 26.71458 -13.85221 13.26043  1.000 28.32465  ? 146 THR   A N    1 
ATOM   2535 C  CA   . THR   A 1 146 ? 25.50452 -13.39925 12.59223  1.000 27.83534  ? 146 THR   A CA   1 
ATOM   2536 C  C    . THR   A 1 146 ? 25.86152 -12.24166 11.67507  1.000 29.68577  ? 146 THR   A C    1 
ATOM   2537 O  O    . THR   A 1 146 ? 26.59636 -11.33506 12.07962  1.000 29.28848  ? 146 THR   A O    1 
ATOM   2538 C  CB   . THR   A 1 146 ? 24.43961 -12.98812 13.61384  1.000 31.07988  ? 146 THR   A CB   1 
ATOM   2539 O  OG1  . THR   A 1 146 ? 24.12016 -14.11620 14.44273  1.000 30.01592  ? 146 THR   A OG1  1 
ATOM   2540 C  CG2  . THR   A 1 146 ? 23.17173 -12.53025 12.91281  1.000 31.71764  ? 146 THR   A CG2  1 
ATOM   2541 H  H    . THR   A 1 146 ? 27.15498 -13.21811 13.63932  1.000 34.00385  ? 146 THR   A H    1 
ATOM   2542 H  HA   . THR   A 1 146 ? 25.13266 -14.10938 12.04603  1.000 33.41668  ? 146 THR   A HA   1 
ATOM   2543 H  HB   . THR   A 1 146 ? 24.77788 -12.25734 14.15461  1.000 37.31013  ? 146 THR   A HB   1 
ATOM   2544 H  HG1  . THR   A 1 146 ? 24.81865 -14.41858 14.79807  1.000 36.03338  ? 146 THR   A HG1  1 
ATOM   2545 H  HG21 . THR   A 1 146 ? 22.46503 -12.39140 13.56257  1.000 38.07544  ? 146 THR   A HG21 1 
ATOM   2546 H  HG22 . THR   A 1 146 ? 23.33488 -11.69777 12.44242  1.000 38.07544  ? 146 THR   A HG22 1 
ATOM   2547 H  HG23 . THR   A 1 146 ? 22.88478 -13.20164 12.27423  1.000 38.07544  ? 146 THR   A HG23 1 
ATOM   2548 N  N    . THR   A 1 147 ? 25.34799 -12.27746 10.44701  1.000 31.07066  ? 147 THR   A N    1 
ATOM   2549 C  CA   . THR   A 1 147 ? 25.70858 -11.29231 9.43642   1.000 31.76959  ? 147 THR   A CA   1 
ATOM   2550 C  C    . THR   A 1 147 ? 24.47018 -10.63727 8.84336   1.000 41.46849  ? 147 THR   A C    1 
ATOM   2551 O  O    . THR   A 1 147 ? 23.35266 -11.16759 8.90016   1.000 33.48254  ? 147 THR   A O    1 
ATOM   2552 C  CB   . THR   A 1 147 ? 26.51242 -11.91908 8.29757   1.000 27.60691  ? 147 THR   A CB   1 
ATOM   2553 O  OG1  . THR   A 1 147 ? 25.67800 -12.83591 7.56556   1.000 33.33212  ? 147 THR   A OG1  1 
ATOM   2554 C  CG2  . THR   A 1 147 ? 27.71316 -12.66240 8.83887   1.000 29.23429  ? 147 THR   A CG2  1 
ATOM   2555 H  H    . THR   A 1 147 ? 24.78477 -12.86807 10.17577  1.000 37.29906  ? 147 THR   A H    1 
ATOM   2556 H  HA   . THR   A 1 147 ? 26.23732 -10.60547 9.87183   1.000 38.13778  ? 147 THR   A HA   1 
ATOM   2557 H  HB   . THR   A 1 147 ? 26.82715 -11.22011 7.70319   1.000 33.14256  ? 147 THR   A HB   1 
ATOM   2558 H  HG1  . THR   A 1 147 ? 26.12220 -13.20366 6.95478   1.000 40.01281  ? 147 THR   A HG1  1 
ATOM   2559 H  HG21 . THR   A 1 147 ? 28.25000 -13.00353 8.10652   1.000 35.09543  ? 147 THR   A HG21 1 
ATOM   2560 H  HG22 . THR   A 1 147 ? 28.25729 -12.06649 9.37712   1.000 35.09543  ? 147 THR   A HG22 1 
ATOM   2561 H  HG23 . THR   A 1 147 ? 27.42238 -13.40637 9.38921   1.000 35.09543  ? 147 THR   A HG23 1 
ATOM   2562 N  N    . SER   A 1 148 ? 24.68924 -9.46678  8.23818   1.000 35.82526  ? 148 SER   A N    1 
ATOM   2563 C  CA   . SER   A 1 148 ? 23.59781 -8.79258  7.54298   1.000 34.28976  ? 148 SER   A CA   1 
ATOM   2564 C  C    . SER   A 1 148 ? 23.09686 -9.61960  6.37271   1.000 32.49026  ? 148 SER   A C    1 
ATOM   2565 O  O    . SER   A 1 148 ? 21.91984 -9.51832  6.00019   1.000 40.35534  ? 148 SER   A O    1 
ATOM   2566 C  CB   . SER   A 1 148 ? 24.05130 -7.39985  7.08844   1.000 38.30080  ? 148 SER   A CB   1 
ATOM   2567 O  OG   . SER   A 1 148 ? 24.08809 -6.49835  8.19596   1.000 47.85278  ? 148 SER   A OG   1 
ATOM   2568 H  H    . SER   A 1 148 ? 25.44311 -9.05345  8.21705   1.000 43.00458  ? 148 SER   A H    1 
ATOM   2569 H  HA   . SER   A 1 148 ? 22.85305 -8.66956  8.15215   1.000 41.16198  ? 148 SER   A HA   1 
ATOM   2570 H  HB2  . SER   A 1 148 ? 24.93928 -7.46556  6.70362   1.000 45.97523  ? 148 SER   A HB2  1 
ATOM   2571 H  HB3  . SER   A 1 148 ? 23.42697 -7.06354  6.42662   1.000 45.97523  ? 148 SER   A HB3  1 
ATOM   2572 H  HG   . SER   A 1 148 ? 24.26528 -5.72197  7.92868   1.000 57.43761  ? 148 SER   A HG   1 
ATOM   2573 N  N    . GLU   A 1 149 ? 23.94996 -10.46288 5.79319   1.000 34.31707  ? 149 GLU   A N    1 
ATOM   2574 C  CA   . GLU   A 1 149 ? 23.49622 -11.33089 4.71255   1.000 33.52285  ? 149 GLU   A CA   1 
ATOM   2575 C  C    . GLU   A 1 149 ? 22.48744 -12.34264 5.23199   1.000 36.15714  ? 149 GLU   A C    1 
ATOM   2576 O  O    . GLU   A 1 149 ? 21.52704 -12.69126 4.53691   1.000 31.34224  ? 149 GLU   A O    1 
ATOM   2577 C  CB   . GLU   A 1 149 ? 24.67712 -12.05059 4.05779   1.000 29.21638  ? 149 GLU   A CB   1 
ATOM   2578 C  CG   . GLU   A 1 149 ? 24.28294 -12.94039 2.87649   1.000 34.74646  ? 149 GLU   A CG   1 
ATOM   2579 C  CD   . GLU   A 1 149 ? 25.47254 -13.41329 2.04962   1.000 63.45518  ? 149 GLU   A CD   1 
ATOM   2580 O  OE1  . GLU   A 1 149 ? 26.62855 -13.28509 2.50485   1.000 36.71292  ? 149 GLU   A OE1  1 
ATOM   2581 O  OE2  . GLU   A 1 149 ? 25.25389 -13.91448 0.92391   1.000 42.75088  ? 149 GLU   A OE2  1 
ATOM   2582 H  H    . GLU   A 1 149 ? 24.77942 -10.54969 6.00310   1.000 41.19476  ? 149 GLU   A H    1 
ATOM   2583 H  HA   . GLU   A 1 149 ? 23.07579 -10.78334 4.03115   1.000 40.24170  ? 149 GLU   A HA   1 
ATOM   2584 H  HB2  . GLU   A 1 149 ? 25.30417 -11.38645 3.73126   1.000 35.07392  ? 149 GLU   A HB2  1 
ATOM   2585 H  HB3  . GLU   A 1 149 ? 25.10559 -12.61329 4.72163   1.000 35.07392  ? 149 GLU   A HB3  1 
ATOM   2586 H  HG2  . GLU   A 1 149 ? 23.82543 -13.72595 3.21483   1.000 41.71002  ? 149 GLU   A HG2  1 
ATOM   2587 H  HG3  . GLU   A 1 149 ? 23.69389 -12.44017 2.29023   1.000 41.71002  ? 149 GLU   A HG3  1 
ATOM   2588 N  N    . GLU   A 1 150 ? 22.68755 -12.82462 6.46213   1.000 30.19170  ? 150 GLU   A N    1 
ATOM   2589 C  CA   . GLU   A 1 150 ? 21.71413 -13.73131 7.06030   1.000 31.93112  ? 150 GLU   A CA   1 
ATOM   2590 C  C    . GLU   A 1 150 ? 20.43389 -12.99147 7.41106   1.000 25.60000  ? 150 GLU   A C    1 
ATOM   2591 O  O    . GLU   A 1 150 ? 19.32636 -13.49936 7.16808   1.000 31.73721  ? 150 GLU   A O    1 
ATOM   2592 C  CB   . GLU   A 1 150 ? 22.31369 -14.40491 8.29174   1.000 30.22374  ? 150 GLU   A CB   1 
ATOM   2593 C  CG   . GLU   A 1 150 ? 23.43388 -15.37906 7.96880   1.000 31.85492  ? 150 GLU   A CG   1 
ATOM   2594 C  CD   . GLU   A 1 150 ? 24.11790 -15.92882 9.20470   1.000 33.18559  ? 150 GLU   A CD   1 
ATOM   2595 O  OE1  . GLU   A 1 150 ? 23.93673 -15.35020 10.30931  1.000 30.33608  ? 150 GLU   A OE1  1 
ATOM   2596 O  OE2  . GLU   A 1 150 ? 24.84015 -16.94959 9.08356   1.000 30.58331  ? 150 GLU   A OE2  1 
ATOM   2597 H  H    . GLU   A 1 150 ? 23.36576 -12.64432 6.95924   1.000 36.24431  ? 150 GLU   A H    1 
ATOM   2598 H  HA   . GLU   A 1 150 ? 21.49314 -14.42955 6.42428   1.000 38.33161  ? 150 GLU   A HA   1 
ATOM   2599 H  HB2  . GLU   A 1 150 ? 22.67499 -13.72090 8.87697   1.000 36.28276  ? 150 GLU   A HB2  1 
ATOM   2600 H  HB3  . GLU   A 1 150 ? 21.61475 -14.89778 8.74942   1.000 36.28276  ? 150 GLU   A HB3  1 
ATOM   2601 H  HG2  . GLU   A 1 150 ? 23.06700 -16.12754 7.47273   1.000 38.24017  ? 150 GLU   A HG2  1 
ATOM   2602 H  HG3  . GLU   A 1 150 ? 24.10329 -14.92334 7.43484   1.000 38.24017  ? 150 GLU   A HG3  1 
ATOM   2603 N  N    . ALA   A 1 151 ? 20.56099 -11.79745 7.99964   1.000 33.21612  ? 151 ALA   A N    1 
ATOM   2604 C  CA   . ALA   A 1 151 ? 19.39038 -11.08619 8.49208   1.000 42.02634  ? 151 ALA   A CA   1 
ATOM   2605 C  C    . ALA   A 1 151 ? 18.52774 -10.57118 7.35002   1.000 36.11538  ? 151 ALA   A C    1 
ATOM   2606 O  O    . ALA   A 1 151 ? 17.29317 -10.58702 7.44421   1.000 40.60639  ? 151 ALA   A O    1 
ATOM   2607 C  CB   . ALA   A 1 151 ? 19.82261 -9.92736  9.39801   1.000 42.20824  ? 151 ALA   A CB   1 
ATOM   2608 H  H    . ALA   A 1 151 ? 21.30635 -11.38638 8.12242   1.000 39.87361  ? 151 ALA   A H    1 
ATOM   2609 H  HA   . ALA   A 1 151 ? 18.85510 -11.70105 9.01774   1.000 50.44587  ? 151 ALA   A HA   1 
ATOM   2610 H  HB1  . ALA   A 1 151 ? 19.03268 -9.51192  9.77790   1.000 50.66416  ? 151 ALA   A HB1  1 
ATOM   2611 H  HB2  . ALA   A 1 151 ? 20.38720 -10.27402 10.10650  1.000 50.66416  ? 151 ALA   A HB2  1 
ATOM   2612 H  HB3  . ALA   A 1 151 ? 20.31505 -9.28003  8.86946   1.000 50.66416  ? 151 ALA   A HB3  1 
ATOM   2613 N  N    . GLY   A 1 152 ? 19.15122 -10.11102 6.26485   1.000 30.28934  ? 152 GLY   A N    1 
ATOM   2614 C  CA   . GLY   A 1 152 ? 18.42101 -9.59630  5.12572   1.000 30.76348  ? 152 GLY   A CA   1 
ATOM   2615 C  C    . GLY   A 1 152 ? 18.31150 -8.09407  5.06471   1.000 34.88442  ? 152 GLY   A C    1 
ATOM   2616 O  O    . GLY   A 1 152 ? 17.65606 -7.57587  4.15012   1.000 36.50633  ? 152 GLY   A O    1 
ATOM   2617 H  H    . GLY   A 1 152 ? 20.00582 -10.08955 6.17104   1.000 36.36148  ? 152 GLY   A H    1 
ATOM   2618 H  HA2  . GLY   A 1 152 ? 18.86247 -9.89327  4.31466   1.000 36.93044  ? 152 GLY   A HA2  1 
ATOM   2619 H  HA3  . GLY   A 1 152 ? 17.52092 -9.95732  5.14568   1.000 36.93044  ? 152 GLY   A HA3  1 
ATOM   2620 N  N    . PHE   A 1 153 ? 18.93470 -7.37951  5.99502   1.000 31.68520  ? 153 PHE   A N    1 
ATOM   2621 C  CA   . PHE   A 1 153 ? 18.84681 -5.92787  6.03958   1.000 36.22310  ? 153 PHE   A CA   1 
ATOM   2622 C  C    . PHE   A 1 153 ? 20.15192 -5.35432  6.57373   1.000 35.45272  ? 153 PHE   A C    1 
ATOM   2623 O  O    . PHE   A 1 153 ? 20.80771 -5.96238  7.43034   1.000 36.76625  ? 153 PHE   A O    1 
ATOM   2624 C  CB   . PHE   A 1 153 ? 17.68610 -5.45252  6.92751   1.000 37.96649  ? 153 PHE   A CB   1 
ATOM   2625 C  CG   . PHE   A 1 153 ? 16.34331 -5.90130  6.45813   1.000 37.15089  ? 153 PHE   A CG   1 
ATOM   2626 C  CD1  . PHE   A 1 153 ? 15.81762 -7.10880  6.88317   1.000 38.78125  ? 153 PHE   A CD1  1 
ATOM   2627 C  CD2  . PHE   A 1 153 ? 15.59519 -5.11639  5.59527   1.000 44.43154  ? 153 PHE   A CD2  1 
ATOM   2628 C  CE1  . PHE   A 1 153 ? 14.57185 -7.53068  6.44176   1.000 45.31903  ? 153 PHE   A CE1  1 
ATOM   2629 C  CE2  . PHE   A 1 153 ? 14.34983 -5.53203  5.16760   1.000 40.89003  ? 153 PHE   A CE2  1 
ATOM   2630 C  CZ   . PHE   A 1 153 ? 13.84033 -6.73790  5.58894   1.000 40.09720  ? 153 PHE   A CZ   1 
ATOM   2631 H  H    . PHE   A 1 153 ? 19.42054 -7.71762  6.61891   1.000 38.03651  ? 153 PHE   A H    1 
ATOM   2632 H  HA   . PHE   A 1 153 ? 18.70861 -5.59908  5.13753   1.000 43.48199  ? 153 PHE   A HA   1 
ATOM   2633 H  HB2  . PHE   A 1 153 ? 17.81715 -5.79990  7.82364   1.000 45.57407  ? 153 PHE   A HB2  1 
ATOM   2634 H  HB3  . PHE   A 1 153 ? 17.68418 -4.48267  6.94463   1.000 45.57407  ? 153 PHE   A HB3  1 
ATOM   2635 H  HD1  . PHE   A 1 153 ? 16.30368 -7.64215  7.46984   1.000 46.55177  ? 153 PHE   A HD1  1 
ATOM   2636 H  HD2  . PHE   A 1 153 ? 15.93507 -4.30210  5.30150   1.000 53.33212  ? 153 PHE   A HD2  1 
ATOM   2637 H  HE1  . PHE   A 1 153 ? 14.23160 -8.34939  6.72255   1.000 54.39710  ? 153 PHE   A HE1  1 
ATOM   2638 H  HE2  . PHE   A 1 153 ? 13.85401 -4.99478  4.59278   1.000 49.08231  ? 153 PHE   A HE2  1 
ATOM   2639 H  HZ   . PHE   A 1 153 ? 13.00234 -7.01677  5.29756   1.000 48.13091  ? 153 PHE   A HZ   1 
ATOM   2640 N  N    . PHE   A 1 154 ? 20.50492 -4.17097  6.07512   1.000 37.35179  ? 154 PHE   A N    1 
ATOM   2641 C  CA   . PHE   A 1 154 ? 21.61552 -3.40463  6.61558   1.000 39.35785  ? 154 PHE   A CA   1 
ATOM   2642 C  C    . PHE   A 1 154 ? 21.20476 -2.66689  7.88198   1.000 44.24131  ? 154 PHE   A C    1 
ATOM   2643 O  O    . PHE   A 1 154 ? 20.04879 -2.26876  8.05019   1.000 43.90347  ? 154 PHE   A O    1 
ATOM   2644 C  CB   . PHE   A 1 154 ? 22.11233 -2.36914  5.60120   1.000 41.85356  ? 154 PHE   A CB   1 
ATOM   2645 C  CG   . PHE   A 1 154 ? 22.80328 -2.95604  4.42043   1.000 46.16831  ? 154 PHE   A CG   1 
ATOM   2646 C  CD1  . PHE   A 1 154 ? 24.06172 -3.51924  4.54951   1.000 67.44775  ? 154 PHE   A CD1  1 
ATOM   2647 C  CD2  . PHE   A 1 154 ? 22.21334 -2.91825  3.17154   1.000 42.34353  ? 154 PHE   A CD2  1 
ATOM   2648 C  CE1  . PHE   A 1 154 ? 24.71299 -4.05513  3.45104   1.000 60.48333  ? 154 PHE   A CE1  1 
ATOM   2649 C  CE2  . PHE   A 1 154 ? 22.86053 -3.45237  2.06254   1.000 45.94559  ? 154 PHE   A CE2  1 
ATOM   2650 C  CZ   . PHE   A 1 154 ? 24.11284 -4.02468  2.21336   1.000 51.08290  ? 154 PHE   A CZ   1 
ATOM   2651 H  H    . PHE   A 1 154 ? 20.10938 -3.78779  5.41457   1.000 44.83642  ? 154 PHE   A H    1 
ATOM   2652 H  HA   . PHE   A 1 154 ? 22.33657 -4.01971  6.82214   1.000 47.24369  ? 154 PHE   A HA   1 
ATOM   2653 H  HB2  . PHE   A 1 154 ? 21.35118 -1.86360  5.27564   1.000 50.23855  ? 154 PHE   A HB2  1 
ATOM   2654 H  HB3  . PHE   A 1 154 ? 22.73922 -1.77637  6.04452   1.000 50.23855  ? 154 PHE   A HB3  1 
ATOM   2655 H  HD1  . PHE   A 1 154 ? 24.47403 -3.53783  5.38291   1.000 80.95158  ? 154 PHE   A HD1  1 
ATOM   2656 H  HD2  . PHE   A 1 154 ? 21.37369 -2.53112  3.07141   1.000 50.82651  ? 154 PHE   A HD2  1 
ATOM   2657 H  HE1  . PHE   A 1 154 ? 25.55586 -4.43550  3.54997   1.000 72.59427  ? 154 PHE   A HE1  1 
ATOM   2658 H  HE2  . PHE   A 1 154 ? 22.45548 -3.42550  1.22582   1.000 55.14898  ? 154 PHE   A HE2  1 
ATOM   2659 H  HZ   . PHE   A 1 154 ? 24.54864 -4.38890  1.47693   1.000 61.31375  ? 154 PHE   A HZ   1 
ATOM   2660 N  N    . LYS   A 1 155 ? 22.17191 -2.46962  8.77396   1.000 43.78136  ? 155 LYS   A N    1 
ATOM   2661 C  CA   . LYS   A 1 155 ? 21.95062 -1.61364  9.92761   1.000 45.77186  ? 155 LYS   A CA   1 
ATOM   2662 C  C    . LYS   A 1 155 ? 21.62871 -0.20448  9.44608   1.000 45.59661  ? 155 LYS   A C    1 
ATOM   2663 O  O    . LYS   A 1 155 ? 22.00753 0.18195   8.33950   1.000 46.07892  ? 155 LYS   A O    1 
ATOM   2664 C  CB   . LYS   A 1 155 ? 23.17591 -1.61255  10.83407  1.000 53.76774  ? 155 LYS   A CB   1 
ATOM   2665 C  CG   . LYS   A 1 155 ? 23.36899 -2.92205  11.59884  1.000 42.85969  ? 155 LYS   A CG   1 
ATOM   2666 C  CD   . LYS   A 1 155 ? 24.84185 -3.19641  11.89068  1.000 57.96641  ? 155 LYS   A CD   1 
ATOM   2667 C  CE   . LYS   A 1 155 ? 25.16422 -3.04262  13.37210  1.000 89.23402  ? 155 LYS   A CE   1 
ATOM   2668 N  NZ   . LYS   A 1 155 ? 26.63804 -3.04493  13.62437  1.000 78.78556  ? 155 LYS   A NZ   1 
ATOM   2669 H  H    . LYS   A 1 155 ? 22.95715 -2.81785  8.73215   1.000 52.55190  ? 155 LYS   A H    1 
ATOM   2670 H  HA   . LYS   A 1 155 ? 21.20455 -1.93960  10.45489  1.000 54.94050  ? 155 LYS   A HA   1 
ATOM   2671 H  HB2  . LYS   A 1 155 ? 23.96641 -1.46583  10.29140  1.000 64.53556  ? 155 LYS   A HB2  1 
ATOM   2672 H  HB3  . LYS   A 1 155 ? 23.08309 -0.89916  11.48473  1.000 64.53556  ? 155 LYS   A HB3  1 
ATOM   2673 H  HG2  . LYS   A 1 155 ? 22.89626 -2.87168  12.44435  1.000 51.44590  ? 155 LYS   A HG2  1 
ATOM   2674 H  HG3  . LYS   A 1 155 ? 23.02269 -3.65662  11.06838  1.000 51.44590  ? 155 LYS   A HG3  1 
ATOM   2675 H  HD2  . LYS   A 1 155 ? 25.05680 -4.10451  11.62603  1.000 69.57396  ? 155 LYS   A HD2  1 
ATOM   2676 H  HD3  . LYS   A 1 155 ? 25.38897 -2.56784  11.39423  1.000 69.57396  ? 155 LYS   A HD3  1 
ATOM   2677 H  HE2  . LYS   A 1 155 ? 24.80280 -2.20135  13.69232  1.000 107.09509 ? 155 LYS   A HE2  1 
ATOM   2678 H  HE3  . LYS   A 1 155 ? 24.77108 -3.78097  13.86320  1.000 107.09509 ? 155 LYS   A HE3  1 
ATOM   2679 H  HZ1  . LYS   A 1 155 ? 26.79779 -2.96266  14.49605  1.000 94.55694  ? 155 LYS   A HZ1  1 
ATOM   2680 H  HZ2  . LYS   A 1 155 ? 26.99503 -3.80749  13.33601  1.000 94.55694  ? 155 LYS   A HZ2  1 
ATOM   2681 H  HZ3  . LYS   A 1 155 ? 27.02140 -2.36604  13.19514  1.000 94.55694  ? 155 LYS   A HZ3  1 
ATOM   2682 N  N    . PRO   A 1 156 ? 20.91621 0.58400   10.25592  1.000 48.12048  ? 156 PRO   A N    1 
ATOM   2683 C  CA   . PRO   A 1 156 ? 20.43859 0.29624   11.61205  1.000 50.13472  ? 156 PRO   A CA   1 
ATOM   2684 C  C    . PRO   A 1 156 ? 19.18450 -0.56529  11.68015  1.000 48.05221  ? 156 PRO   A C    1 
ATOM   2685 O  O    . PRO   A 1 156 ? 18.54497 -0.61639  12.71885  1.000 46.20589  ? 156 PRO   A O    1 
ATOM   2686 C  CB   . PRO   A 1 156 ? 20.16161 1.70762   12.17694  1.000 66.67602  ? 156 PRO   A CB   1 
ATOM   2687 C  CG   . PRO   A 1 156 ? 19.70109 2.48109   10.96207  1.000 54.87850  ? 156 PRO   A CG   1 
ATOM   2688 C  CD   . PRO   A 1 156 ? 20.55391 1.94906   9.82015   1.000 52.32055  ? 156 PRO   A CD   1 
ATOM   2689 H  HA   . PRO   A 1 156 ? 21.14998 -0.14944  12.09804  1.000 60.17593  ? 156 PRO   A HA   1 
ATOM   2690 H  HB2  . PRO   A 1 156 ? 19.46946 1.66952   12.85546  1.000 80.02549  ? 156 PRO   A HB2  1 
ATOM   2691 H  HB3  . PRO   A 1 156 ? 20.97248 2.08631   12.55108  1.000 80.02549  ? 156 PRO   A HB3  1 
ATOM   2692 H  HG2  . PRO   A 1 156 ? 18.75936 2.31438   10.80007  1.000 65.86847  ? 156 PRO   A HG2  1 
ATOM   2693 H  HG3  . PRO   A 1 156 ? 19.85177 3.42989   11.09619  1.000 65.86847  ? 156 PRO   A HG3  1 
ATOM   2694 H  HD2  . PRO   A 1 156 ? 20.04451 1.92206   8.99512   1.000 62.79893  ? 156 PRO   A HD2  1 
ATOM   2695 H  HD3  . PRO   A 1 156 ? 21.34786 2.49369   9.70217   1.000 62.79893  ? 156 PRO   A HD3  1 
ATOM   2696 N  N    . HIS   A 1 157 ? 18.78884 -1.24532  10.60606  1.000 50.48135  ? 157 HIS   A N    1 
ATOM   2697 C  CA   . HIS   A 1 157 ? 17.65946 -2.16013  10.70175  1.000 40.88451  ? 157 HIS   A CA   1 
ATOM   2698 C  C    . HIS   A 1 157 ? 17.91459 -3.16218  11.82740  1.000 42.65800  ? 157 HIS   A C    1 
ATOM   2699 O  O    . HIS   A 1 157 ? 19.02590 -3.67560  11.95983  1.000 42.82550  ? 157 HIS   A O    1 
ATOM   2700 C  CB   . HIS   A 1 157 ? 17.44633 -2.88373  9.37716   1.000 39.30206  ? 157 HIS   A CB   1 
ATOM   2701 C  CG   . HIS   A 1 157 ? 16.09789 -3.50938  9.23905   1.000 39.45831  ? 157 HIS   A CG   1 
ATOM   2702 N  ND1  . HIS   A 1 157 ? 15.69629 -4.58374  9.99996   1.000 42.81707  ? 157 HIS   A ND1  1 
ATOM   2703 C  CD2  . HIS   A 1 157 ? 15.06771 -3.23130  8.40595   1.000 42.29312  ? 157 HIS   A CD2  1 
ATOM   2704 C  CE1  . HIS   A 1 157 ? 14.47191 -4.93413  9.65083   1.000 42.70583  ? 157 HIS   A CE1  1 
ATOM   2705 N  NE2  . HIS   A 1 157 ? 14.06844 -4.12921  8.68398   1.000 46.21911  ? 157 HIS   A NE2  1 
ATOM   2706 H  H    . HIS   A 1 157 ? 19.15040 -1.19529  9.82736   1.000 60.59189  ? 157 HIS   A H    1 
ATOM   2707 H  HA   . HIS   A 1 157 ? 16.84753 -1.66942  10.90389  1.000 49.07569  ? 157 HIS   A HA   1 
ATOM   2708 H  HB2  . HIS   A 1 157 ? 17.55154 -2.24612  8.65378   1.000 47.17674  ? 157 HIS   A HB2  1 
ATOM   2709 H  HB3  . HIS   A 1 157 ? 18.10832 -3.58821  9.29735   1.000 47.17674  ? 157 HIS   A HB3  1 
ATOM   2710 H  HD2  . HIS   A 1 157 ? 15.04219 -2.55776  7.76518   1.000 50.76601  ? 157 HIS   A HD2  1 
ATOM   2711 H  HE1  . HIS   A 1 157 ? 13.97786 -5.62903  10.02221  1.000 51.26126  ? 157 HIS   A HE1  1 
ATOM   2712 H  HE2  . HIS   A 1 157 ? 13.30347 -4.16269  8.29242   1.000 55.47720  ? 157 HIS   A HE2  1 
ATOM   2713 N  N    . PRO   A 1 158 ? 16.92306 -3.44078  12.67483  1.000 46.55620  ? 158 PRO   A N    1 
ATOM   2714 C  CA   . PRO   A 1 158 ? 17.17602 -4.28533  13.85005  1.000 41.70172  ? 158 PRO   A CA   1 
ATOM   2715 C  C    . PRO   A 1 158 ? 17.18967 -5.78272  13.58621  1.000 35.86881  ? 158 PRO   A C    1 
ATOM   2716 O  O    . PRO   A 1 158 ? 17.48385 -6.54451  14.51460  1.000 41.35418  ? 158 PRO   A O    1 
ATOM   2717 C  CB   . PRO   A 1 158 ? 16.01148 -3.91752  14.79207  1.000 51.55121  ? 158 PRO   A CB   1 
ATOM   2718 C  CG   . PRO   A 1 158 ? 14.89770 -3.52106  13.86484  1.000 42.36489  ? 158 PRO   A CG   1 
ATOM   2719 C  CD   . PRO   A 1 158 ? 15.56770 -2.84410  12.68774  1.000 44.44545  ? 158 PRO   A CD   1 
ATOM   2720 H  HA   . PRO   A 1 158 ? 18.02108 -4.03082  14.25253  1.000 50.05634  ? 158 PRO   A HA   1 
ATOM   2721 H  HB2  . PRO   A 1 158 ? 15.76252 -4.68547  15.32982  1.000 61.87572  ? 158 PRO   A HB2  1 
ATOM   2722 H  HB3  . PRO   A 1 158 ? 16.26801 -3.17930  15.36664  1.000 61.87572  ? 158 PRO   A HB3  1 
ATOM   2723 H  HG2  . PRO   A 1 158 ? 14.41315 -4.31080  13.57774  1.000 50.85214  ? 158 PRO   A HG2  1 
ATOM   2724 H  HG3  . PRO   A 1 158 ? 14.29634 -2.90911  14.31737  1.000 50.85214  ? 158 PRO   A HG3  1 
ATOM   2725 H  HD2  . PRO   A 1 158 ? 15.09653 -3.04058  11.86294  1.000 53.34881  ? 158 PRO   A HD2  1 
ATOM   2726 H  HD3  . PRO   A 1 158 ? 15.61455 -1.88466  12.82257  1.000 53.34881  ? 158 PRO   A HD3  1 
ATOM   2727 N  N    . ARG   A 1 159 ? 16.92441 -6.23551  12.36388  1.000 37.26986  ? 159 ARG   A N    1 
ATOM   2728 C  CA   A ARG   A 1 159 ? 16.76138 -7.66806  12.12883  0.700 39.73569  ? 159 ARG   A CA   1 
ATOM   2729 C  CA   B ARG   A 1 159 ? 16.75409 -7.66750  12.14583  0.300 39.69458  ? 159 ARG   A CA   1 
ATOM   2730 C  C    . ARG   A 1 159 ? 18.02174 -8.43264  12.49308  1.000 33.26694  ? 159 ARG   A C    1 
ATOM   2731 O  O    . ARG   A 1 159 ? 17.94797 -9.54492  13.02286  1.000 32.14724  ? 159 ARG   A O    1 
ATOM   2732 C  CB   A ARG   A 1 159 ? 16.39452 -7.92113  10.66456  0.700 40.01628  ? 159 ARG   A CB   1 
ATOM   2733 C  CB   B ARG   A 1 159 ? 16.34008 -7.94352  10.69911  0.300 40.35597  ? 159 ARG   A CB   1 
ATOM   2734 C  CG   A ARG   A 1 159 ? 15.97642 -9.35270  10.34656  0.700 41.46201  ? 159 ARG   A CG   1 
ATOM   2735 C  CG   B ARG   A 1 159 ? 15.95294 -9.39917  10.43368  0.300 41.10185  ? 159 ARG   A CG   1 
ATOM   2736 C  CD   A ARG   A 1 159 ? 14.60866 -9.69530  10.91872  0.700 38.66420  ? 159 ARG   A CD   1 
ATOM   2737 C  CD   B ARG   A 1 159 ? 14.77265 -9.50791  9.46755   0.300 46.23393  ? 159 ARG   A CD   1 
ATOM   2738 N  NE   A ARG   A 1 159 ? 13.54047 -8.87549  10.36083  0.700 56.20515  ? 159 ARG   A NE   1 
ATOM   2739 N  NE   B ARG   A 1 159 ? 15.03046 -10.43413 8.36765   0.300 51.44507  ? 159 ARG   A NE   1 
ATOM   2740 C  CZ   A ARG   A 1 159 ? 12.83907 -9.18799  9.27814   0.700 63.95426  ? 159 ARG   A CZ   1 
ATOM   2741 C  CZ   B ARG   A 1 159 ? 14.34957 -11.54838 8.13150   0.300 28.43755  ? 159 ARG   A CZ   1 
ATOM   2742 N  NH1  A ARG   A 1 159 ? 13.05978 -10.30996 8.60906   0.700 58.54822  ? 159 ARG   A NH1  1 
ATOM   2743 N  NH1  B ARG   A 1 159 ? 13.33266 -11.91637 8.89384   0.300 46.25583  ? 159 ARG   A NH1  1 
ATOM   2744 N  NH2  A ARG   A 1 159 ? 11.89170 -8.35442  8.85607   0.700 62.43976  ? 159 ARG   A NH2  1 
ATOM   2745 N  NH2  B ARG   A 1 159 ? 14.68230 -12.29894 7.08724   0.300 44.68095  ? 159 ARG   A NH2  1 
ATOM   2746 H  H    A ARG   A 1 159 ? 16.83507 -5.74374  11.66404  0.700 44.73810  ? 159 ARG   A H    1 
ATOM   2747 H  H    B ARG   A 1 159 ? 16.84005 -5.74714  11.66105  0.300 44.73810  ? 159 ARG   A H    1 
ATOM   2748 H  HA   A ARG   A 1 159 ? 16.03671 -7.99336  12.68554  0.700 47.69710  ? 159 ARG   A HA   1 
ATOM   2749 H  HA   B ARG   A 1 159 ? 16.04165 -7.98370  12.72320  0.300 47.64777  ? 159 ARG   A HA   1 
ATOM   2750 H  HB2  A ARG   A 1 159 ? 15.65311 -7.34181  10.42876  0.700 48.03381  ? 159 ARG   A HB2  1 
ATOM   2751 H  HB2  B ARG   A 1 159 ? 15.57357 -7.38959  10.48344  0.300 48.44143  ? 159 ARG   A HB2  1 
ATOM   2752 H  HB3  A ARG   A 1 159 ? 17.16575 -7.71367  10.11405  0.700 48.03381  ? 159 ARG   A HB3  1 
ATOM   2753 H  HB3  B ARG   A 1 159 ? 17.08291 -7.72387  10.11528  0.300 48.44143  ? 159 ARG   A HB3  1 
ATOM   2754 H  HG2  A ARG   A 1 159 ? 15.93772 -9.46661  9.38405   0.700 49.76869  ? 159 ARG   A HG2  1 
ATOM   2755 H  HG2  B ARG   A 1 159 ? 16.70869 -9.86495  10.04278  0.300 49.33649  ? 159 ARG   A HG2  1 
ATOM   2756 H  HG3  A ARG   A 1 159 ? 16.62466 -9.96563  10.72737  0.700 49.76869  ? 159 ARG   A HG3  1 
ATOM   2757 H  HG3  B ARG   A 1 159 ? 15.70005 -9.82048  11.27000  0.300 49.33649  ? 159 ARG   A HG3  1 
ATOM   2758 H  HD2  A ARG   A 1 159 ? 14.40742 -10.62360 10.72208  0.700 46.41131  ? 159 ARG   A HD2  1 
ATOM   2759 H  HD2  B ARG   A 1 159 ? 13.99489 -9.82606  9.95208   0.300 55.49498  ? 159 ARG   A HD2  1 
ATOM   2760 H  HD3  A ARG   A 1 159 ? 14.62351 -9.55515  11.87842  0.700 46.41131  ? 159 ARG   A HD3  1 
ATOM   2761 H  HD3  B ARG   A 1 159 ? 14.59233 -8.63366  9.08799   0.300 55.49498  ? 159 ARG   A HD3  1 
ATOM   2762 H  HE   A ARG   A 1 159 ? 13.35152 -8.13806  10.76094  0.700 67.46045  ? 159 ARG   A HE   1 
ATOM   2763 H  HE   B ARG   A 1 159 ? 15.67432 -10.24212 7.83083   0.300 61.74835  ? 159 ARG   A HE   1 
ATOM   2764 H  HH11 A ARG   A 1 159 ? 13.66946 -10.85566 8.87382   0.700 70.27214  ? 159 ARG   A HH11 1 
ATOM   2765 H  HH11 B ARG   A 1 159 ? 13.09789 -11.42888 9.56230   0.300 55.52127  ? 159 ARG   A HH11 1 
ATOM   2766 H  HH12 A ARG   A 1 159 ? 12.59338 -10.49256 7.90997   0.700 70.27214  ? 159 ARG   A HH12 1 
ATOM   2767 H  HH12 B ARG   A 1 159 ? 12.90647 -12.64304 8.72089   0.300 55.52127  ? 159 ARG   A HH12 1 
ATOM   2768 H  HH21 A ARG   A 1 159 ? 11.74024 -7.62372  9.28355   0.700 74.94199  ? 159 ARG   A HH21 1 
ATOM   2769 H  HH21 B ARG   A 1 159 ? 15.33092 -12.06032 6.57541   0.300 53.63141  ? 159 ARG   A HH21 1 
ATOM   2770 H  HH22 A ARG   A 1 159 ? 11.43085 -8.54635  8.15580   0.700 74.94199  ? 159 ARG   A HH22 1 
ATOM   2771 H  HH22 B ARG   A 1 159 ? 14.24911 -13.02349 6.92299   0.300 53.63141  ? 159 ARG   A HH22 1 
ATOM   2772 N  N    . ILE   A 1 160 ? 19.19516 -7.84877  12.21778  1.000 31.95458  ? 160 ILE   A N    1 
ATOM   2773 C  CA   . ILE   A 1 160 ? 20.44253 -8.55312  12.51253  1.000 30.14999  ? 160 ILE   A CA   1 
ATOM   2774 C  C    . ILE   A 1 160 ? 20.58163 -8.78690  14.01936  1.000 27.02891  ? 160 ILE   A C    1 
ATOM   2775 O  O    . ILE   A 1 160 ? 21.08765 -9.83415  14.46252  1.000 31.45658  ? 160 ILE   A O    1 
ATOM   2776 C  CB   . ILE   A 1 160 ? 21.64710 -7.78687  11.93417  1.000 34.37963  ? 160 ILE   A CB   1 
ATOM   2777 C  CG1  . ILE   A 1 160 ? 22.89858 -8.66312  12.01914  1.000 31.65540  ? 160 ILE   A CG1  1 
ATOM   2778 C  CG2  . ILE   A 1 160 ? 21.86240 -6.47777  12.65454  1.000 36.44986  ? 160 ILE   A CG2  1 
ATOM   2779 C  CD1  . ILE   A 1 160 ? 24.11508 -8.10179  11.29887  1.000 39.12227  ? 160 ILE   A CD1  1 
ATOM   2780 H  H    . ILE   A 1 160 ? 19.29106 -7.06797  11.87029  1.000 38.35977  ? 160 ILE   A H    1 
ATOM   2781 H  HA   . ILE   A 1 160 ? 20.41414 -9.42101  12.08025  1.000 36.19426  ? 160 ILE   A HA   1 
ATOM   2782 H  HB   . ILE   A 1 160 ? 21.46218 -7.58131  11.00441  1.000 41.26982  ? 160 ILE   A HB   1 
ATOM   2783 H  HG12 . ILE   A 1 160 ? 23.13624 -8.77190  12.95326  1.000 38.00075  ? 160 ILE   A HG12 1 
ATOM   2784 H  HG13 . ILE   A 1 160 ? 22.69807 -9.52651  11.62511  1.000 38.00075  ? 160 ILE   A HG13 1 
ATOM   2785 H  HG21 . ILE   A 1 160 ? 22.51377 -5.95139  12.16510  1.000 43.75411  ? 160 ILE   A HG21 1 
ATOM   2786 H  HG22 . ILE   A 1 160 ? 21.01920 -6.00056  12.70115  1.000 43.75411  ? 160 ILE   A HG22 1 
ATOM   2787 H  HG23 . ILE   A 1 160 ? 22.18936 -6.65980  13.54944  1.000 43.75411  ? 160 ILE   A HG23 1 
ATOM   2788 H  HD11 . ILE   A 1 160 ? 24.84422 -8.73780  11.36776  1.000 46.96099  ? 160 ILE   A HD11 1 
ATOM   2789 H  HD12 . ILE   A 1 160 ? 23.89055 -7.95569  10.36659  1.000 46.96099  ? 160 ILE   A HD12 1 
ATOM   2790 H  HD13 . ILE   A 1 160 ? 24.36815 -7.26225  11.71365  1.000 46.96099  ? 160 ILE   A HD13 1 
ATOM   2791 N  N    . PHE   A 1 161 ? 20.15120 -7.82289  14.83072  1.000 28.61633  ? 161 PHE   A N    1 
ATOM   2792 C  CA   . PHE   A 1 161 ? 20.22022 -8.00713  16.27796  1.000 30.40248  ? 161 PHE   A CA   1 
ATOM   2793 C  C    . PHE   A 1 161 ? 19.15619 -8.98833  16.74816  1.000 29.80557  ? 161 PHE   A C    1 
ATOM   2794 O  O    . PHE   A 1 161 ? 19.39524 -9.77792  17.67699  1.000 29.09178  ? 161 PHE   A O    1 
ATOM   2795 C  CB   . PHE   A 1 161 ? 20.07087 -6.66105  16.98769  1.000 38.89873  ? 161 PHE   A CB   1 
ATOM   2796 C  CG   . PHE   A 1 161 ? 21.23479 -5.72416  16.74627  1.000 33.58520  ? 161 PHE   A CG   1 
ATOM   2797 C  CD1  . PHE   A 1 161 ? 22.40098 -5.85469  17.47724  1.000 39.79837  ? 161 PHE   A CD1  1 
ATOM   2798 C  CD2  . PHE   A 1 161 ? 21.14777 -4.72312  15.79538  1.000 42.49162  ? 161 PHE   A CD2  1 
ATOM   2799 C  CE1  . PHE   A 1 161 ? 23.46939 -4.99974  17.26395  1.000 43.60906  ? 161 PHE   A CE1  1 
ATOM   2800 C  CE2  . PHE   A 1 161 ? 22.20563 -3.87057  15.57150  1.000 40.06295  ? 161 PHE   A CE2  1 
ATOM   2801 C  CZ   . PHE   A 1 161 ? 23.36974 -4.01033  16.30231  1.000 43.20709  ? 161 PHE   A CZ   1 
ATOM   2802 H  H    . PHE   A 1 161 ? 19.82249 -7.07027  14.57553  1.000 34.35387  ? 161 PHE   A H    1 
ATOM   2803 H  HA   . PHE   A 1 161 ? 21.08983 -8.36755  16.51201  1.000 36.49725  ? 161 PHE   A HA   1 
ATOM   2804 H  HB2  . PHE   A 1 161 ? 19.26595 -6.22502  16.66693  1.000 46.69275  ? 161 PHE   A HB2  1 
ATOM   2805 H  HB3  . PHE   A 1 161 ? 20.00615 -6.81575  17.94308  1.000 46.69275  ? 161 PHE   A HB3  1 
ATOM   2806 H  HD1  . PHE   A 1 161 ? 22.46875 -6.52406  18.11931  1.000 47.77232  ? 161 PHE   A HD1  1 
ATOM   2807 H  HD2  . PHE   A 1 161 ? 20.36579 -4.62485  15.30167  1.000 51.00422  ? 161 PHE   A HD2  1 
ATOM   2808 H  HE1  . PHE   A 1 161 ? 24.24844 -5.09016  17.76376  1.000 52.34514  ? 161 PHE   A HE1  1 
ATOM   2809 H  HE2  . PHE   A 1 161 ? 22.13659 -3.20156  14.92920  1.000 48.08981  ? 161 PHE   A HE2  1 
ATOM   2810 H  HZ   . PHE   A 1 161 ? 24.08691 -3.43880  16.14763  1.000 51.86278  ? 161 PHE   A HZ   1 
ATOM   2811 N  N    . GLU   A 1 162 ? 17.97775 -8.94271  16.12666  1.000 31.07870  ? 162 GLU   A N    1 
ATOM   2812 C  CA   . GLU   A 1 162 ? 16.93046 -9.90162  16.46695  1.000 30.59310  ? 162 GLU   A CA   1 
ATOM   2813 C  C    . GLU   A 1 162 ? 17.40364 -11.32220 16.21211  1.000 30.66157  ? 162 GLU   A C    1 
ATOM   2814 O  O    . GLU   A 1 162 ? 17.15779 -12.22941 17.01428  1.000 30.02589  ? 162 GLU   A O    1 
ATOM   2815 C  CB   . GLU   A 1 162 ? 15.67063 -9.61071  15.64918  1.000 36.59876  ? 162 GLU   A CB   1 
ATOM   2816 C  CG   . GLU   A 1 162 ? 14.97148 -8.31164  15.98619  1.000 42.58706  ? 162 GLU   A CG   1 
ATOM   2817 C  CD   . GLU   A 1 162 ? 13.89137 -7.94740  14.96263  1.000 51.84612  ? 162 GLU   A CD   1 
ATOM   2818 O  OE1  . GLU   A 1 162 ? 13.57783 -8.78570  14.08930  1.000 62.46594  ? 162 GLU   A OE1  1 
ATOM   2819 O  OE2  . GLU   A 1 162 ? 13.36369 -6.82333  15.02973  1.000 67.86015  ? 162 GLU   A OE2  1 
ATOM   2820 H  H    . GLU   A 1 162 ? 17.76331 -8.37683  15.51560  1.000 37.30871  ? 162 GLU   A H    1 
ATOM   2821 H  HA   . GLU   A 1 162 ? 16.70899 -9.81116  17.40698  1.000 36.72599  ? 162 GLU   A HA   1 
ATOM   2822 H  HB2  . GLU   A 1 162 ? 15.91576 -9.57363  14.71140  1.000 43.93278  ? 162 GLU   A HB2  1 
ATOM   2823 H  HB3  . GLU   A 1 162 ? 15.03598 -10.32902 15.79804  1.000 43.93278  ? 162 GLU   A HB3  1 
ATOM   2824 H  HG2  . GLU   A 1 162 ? 14.54779 -8.39517  16.85476  1.000 51.11874  ? 162 GLU   A HG2  1 
ATOM   2825 H  HG3  . GLU   A 1 162 ? 15.62465 -7.59471  16.00325  1.000 51.11874  ? 162 GLU   A HG3  1 
ATOM   2826 N  N    . LEU   A 1 163 ? 18.09657 -11.53280 15.09648  1.000 28.71342  ? 163 LEU   A N    1 
ATOM   2827 C  CA   . LEU   A 1 163 ? 18.58450 -12.86836 14.77094  1.000 29.08685  ? 163 LEU   A CA   1 
ATOM   2828 C  C    . LEU   A 1 163 ? 19.70083 -13.28722 15.70746  1.000 27.60125  ? 163 LEU   A C    1 
ATOM   2829 O  O    . LEU   A 1 163 ? 19.73814 -14.42832 16.16320  1.000 27.10498  ? 163 LEU   A O    1 
ATOM   2830 C  CB   . LEU   A 1 163 ? 19.03402 -12.91374 13.30876  1.000 26.96148  ? 163 LEU   A CB   1 
ATOM   2831 C  CG   . LEU   A 1 163 ? 19.70938 -14.20330 12.83744  1.000 27.16141  ? 163 LEU   A CG   1 
ATOM   2832 C  CD1  . LEU   A 1 163 ? 18.75722 -15.37238 12.96137  1.000 27.81275  ? 163 LEU   A CD1  1 
ATOM   2833 C  CD2  . LEU   A 1 163 ? 20.21310 -14.05911 11.41554  1.000 25.49828  ? 163 LEU   A CD2  1 
ATOM   2834 H  H    . LEU   A 1 163 ? 18.29548 -10.92789 14.51845  1.000 34.47037  ? 163 LEU   A H    1 
ATOM   2835 H  HA   . LEU   A 1 163 ? 17.86298 -13.50816 14.87563  1.000 34.91850  ? 163 LEU   A HA   1 
ATOM   2836 H  HB2  . LEU   A 1 163 ? 18.25179 -12.78205 12.75047  1.000 32.36805  ? 163 LEU   A HB2  1 
ATOM   2837 H  HB3  . LEU   A 1 163 ? 19.66760 -12.19297 13.16745  1.000 32.36805  ? 163 LEU   A HB3  1 
ATOM   2838 H  HG   . LEU   A 1 163 ? 20.47780 -14.38305 13.40146  1.000 32.60797  ? 163 LEU   A HG   1 
ATOM   2839 H  HD11 . LEU   A 1 163 ? 19.17960 -16.16409 12.59303  1.000 33.38957  ? 163 LEU   A HD11 1 
ATOM   2840 H  HD12 . LEU   A 1 163 ? 18.55057 -15.51338 13.89855  1.000 33.38957  ? 163 LEU   A HD12 1 
ATOM   2841 H  HD13 . LEU   A 1 163 ? 17.94522 -15.17177 12.47014  1.000 33.38957  ? 163 LEU   A HD13 1 
ATOM   2842 H  HD21 . LEU   A 1 163 ? 20.67927 -14.87102 11.16179  1.000 30.61221  ? 163 LEU   A HD21 1 
ATOM   2843 H  HD22 . LEU   A 1 163 ? 19.45679 -13.91385 10.82579  1.000 30.61221  ? 163 LEU   A HD22 1 
ATOM   2844 H  HD23 . LEU   A 1 163 ? 20.81815 -13.30231 11.37007  1.000 30.61221  ? 163 LEU   A HD23 1 
ATOM   2845 N  N    . ALA   A 1 164 ? 20.64128 -12.39162 15.99529  1.000 29.34138  ? 164 ALA   A N    1 
ATOM   2846 C  CA   . ALA   A 1 164 ? 21.72564 -12.74086 16.90647  1.000 30.48576  ? 164 ALA   A CA   1 
ATOM   2847 C  C    . ALA   A 1 164 ? 21.18609 -13.14336 18.27844  1.000 24.95128  ? 164 ALA   A C    1 
ATOM   2848 O  O    . ALA   A 1 164 ? 21.65572 -14.11336 18.87542  1.000 28.62568  ? 164 ALA   A O    1 
ATOM   2849 C  CB   . ALA   A 1 164 ? 22.70223 -11.55952 17.03749  1.000 31.97236  ? 164 ALA   A CB   1 
ATOM   2850 H  H    . ALA   A 1 164 ? 20.67443 -11.59100 15.68304  1.000 35.22392  ? 164 ALA   A H    1 
ATOM   2851 H  HA   . ALA   A 1 164 ? 22.21194 -13.49621 16.54060  1.000 36.59718  ? 164 ALA   A HA   1 
ATOM   2852 H  HB1  . ALA   A 1 164 ? 23.43740 -11.82000 17.61418  1.000 38.38111  ? 164 ALA   A HB1  1 
ATOM   2853 H  HB2  . ALA   A 1 164 ? 23.03811 -11.32833 16.15736  1.000 38.38111  ? 164 ALA   A HB2  1 
ATOM   2854 H  HB3  . ALA   A 1 164 ? 22.23262 -10.80268 17.42163  1.000 38.38111  ? 164 ALA   A HB3  1 
ATOM   2855 N  N    . LEU   A 1 165 ? 20.16141 -12.43952 18.76270  1.000 26.47690  ? 165 LEU   A N    1 
ATOM   2856 C  CA   . LEU   A 1 165 ? 19.55625 -12.76357 20.04689  1.000 31.83469  ? 165 LEU   A CA   1 
ATOM   2857 C  C    . LEU   A 1 165 ? 18.84420 -14.11070 20.00268  1.000 27.67911  ? 165 LEU   A C    1 
ATOM   2858 O  O    . LEU   A 1 165 ? 18.91008 -14.87840 20.96959  1.000 28.27522  ? 165 LEU   A O    1 
ATOM   2859 C  CB   . LEU   A 1 165 ? 18.58827 -11.65262 20.44968  1.000 29.20489  ? 165 LEU   A CB   1 
ATOM   2860 C  CG   . LEU   A 1 165 ? 19.22904 -10.30294 20.82585  1.000 30.36440  ? 165 LEU   A CG   1 
ATOM   2861 C  CD1  . LEU   A 1 165 ? 18.17404 -9.22332  20.90599  1.000 34.77602  ? 165 LEU   A CD1  1 
ATOM   2862 C  CD2  . LEU   A 1 165 ? 19.96054 -10.41447 22.13878  1.000 32.46786  ? 165 LEU   A CD2  1 
ATOM   2863 H  H    . LEU   A 1 165 ? 19.79910 -11.76878 18.36464  1.000 31.78655  ? 165 LEU   A H    1 
ATOM   2864 H  HA   . LEU   A 1 165 ? 20.25212 -12.82139 20.72019  1.000 38.21590  ? 165 LEU   A HA   1 
ATOM   2865 H  HB2  . LEU   A 1 165 ? 17.98921 -11.48853 19.70464  1.000 35.06013  ? 165 LEU   A HB2  1 
ATOM   2866 H  HB3  . LEU   A 1 165 ? 18.08364 -11.95587 21.22058  1.000 35.06013  ? 165 LEU   A HB3  1 
ATOM   2867 H  HG   . LEU   A 1 165 ? 19.86913 -10.05535 20.14037  1.000 36.45155  ? 165 LEU   A HG   1 
ATOM   2868 H  HD11 . LEU   A 1 165 ? 18.59379 -8.39086  21.17380  1.000 41.74549  ? 165 LEU   A HD11 1 
ATOM   2869 H  HD12 . LEU   A 1 165 ? 17.76099 -9.12008  20.03442  1.000 41.74549  ? 165 LEU   A HD12 1 
ATOM   2870 H  HD13 . LEU   A 1 165 ? 17.50614 -9.48236  21.55997  1.000 41.74549  ? 165 LEU   A HD13 1 
ATOM   2871 H  HD21 . LEU   A 1 165 ? 20.33151 -9.54806  22.36819  1.000 38.97571  ? 165 LEU   A HD21 1 
ATOM   2872 H  HD22 . LEU   A 1 165 ? 19.33662 -10.69927 22.82472  1.000 38.97571  ? 165 LEU   A HD22 1 
ATOM   2873 H  HD23 . LEU   A 1 165 ? 20.67334 -11.06617 22.04879  1.000 38.97571  ? 165 LEU   A HD23 1 
ATOM   2874 N  N    . LYS   A 1 166 ? 18.15018 -14.40522 18.89592  1.000 28.97313  ? 166 LYS   A N    1 
ATOM   2875 C  CA   . LYS   A 1 166 ? 17.51826 -15.70538 18.72914  1.000 33.84958  ? 166 LYS   A CA   1 
ATOM   2876 C  C    . LYS   A 1 166 ? 18.54356 -16.82161 18.78768  1.000 27.02265  ? 166 LYS   A C    1 
ATOM   2877 O  O    . LYS   A 1 166 ? 18.31087 -17.85746 19.41897  1.000 30.11610  ? 166 LYS   A O    1 
ATOM   2878 C  CB   . LYS   A 1 166 ? 16.77481 -15.76350 17.39253  1.000 30.69090  ? 166 LYS   A CB   1 
ATOM   2879 C  CG   . LYS   A 1 166 ? 15.42979 -15.05207 17.38356  1.000 33.08721  ? 166 LYS   A CG   1 
ATOM   2880 C  CD   . LYS   A 1 166 ? 14.45169 -15.72959 18.32439  1.000 38.03946  ? 166 LYS   A CD   1 
ATOM   2881 C  CE   . LYS   A 1 166 ? 13.05384 -15.12658 18.20772  1.000 49.48298  ? 166 LYS   A CE   1 
ATOM   2882 N  NZ   . LYS   A 1 166 ? 12.09938 -15.82492 19.12332  1.000 54.80226  ? 166 LYS   A NZ   1 
ATOM   2883 H  H    . LYS   A 1 166 ? 18.03413 -13.86893 18.23371  1.000 34.78203  ? 166 LYS   A H    1 
ATOM   2884 H  HA   . LYS   A 1 166 ? 16.87712 -15.82955 19.44638  1.000 40.63376  ? 166 LYS   A HA   1 
ATOM   2885 H  HB2  . LYS   A 1 166 ? 17.32928 -15.34922 16.71296  1.000 36.84335  ? 166 LYS   A HB2  1 
ATOM   2886 H  HB3  . LYS   A 1 166 ? 16.61509 -16.69371 17.16868  1.000 36.84335  ? 166 LYS   A HB3  1 
ATOM   2887 H  HG2  . LYS   A 1 166 ? 15.54780 -14.13362 17.67238  1.000 39.71893  ? 166 LYS   A HG2  1 
ATOM   2888 H  HG3  . LYS   A 1 166 ? 15.05882 -15.07302 16.48754  1.000 39.71893  ? 166 LYS   A HG3  1 
ATOM   2889 H  HD2  . LYS   A 1 166 ? 14.39603 -16.67288 18.10525  1.000 45.66162  ? 166 LYS   A HD2  1 
ATOM   2890 H  HD3  . LYS   A 1 166 ? 14.75614 -15.61881 19.23869  1.000 45.66162  ? 166 LYS   A HD3  1 
ATOM   2891 H  HE2  . LYS   A 1 166 ? 13.08418 -14.18812 18.45117  1.000 59.39384  ? 166 LYS   A HE2  1 
ATOM   2892 H  HE3  . LYS   A 1 166 ? 12.73412 -15.22291 17.29701  1.000 59.39384  ? 166 LYS   A HE3  1 
ATOM   2893 H  HZ1  . LYS   A 1 166 ? 11.28589 -15.47350 19.04059  1.000 65.77698  ? 166 LYS   A HZ1  1 
ATOM   2894 H  HZ2  . LYS   A 1 166 ? 12.06188 -16.69082 18.92105  1.000 65.77698  ? 166 LYS   A HZ2  1 
ATOM   2895 H  HZ3  . LYS   A 1 166 ? 12.36759 -15.73682 19.96736  1.000 65.77698  ? 166 LYS   A HZ3  1 
ATOM   2896 N  N    . LYS   A 1 167 ? 19.68795 -16.64599 18.11106  1.000 26.34094  ? 167 LYS   A N    1 
ATOM   2897 C  CA   . LYS   A 1 167 ? 20.71877 -17.67818 18.17582  1.000 29.45307  ? 167 LYS   A CA   1 
ATOM   2898 C  C    . LYS   A 1 167 ? 21.18243 -17.91191 19.61072  1.000 30.19981  ? 167 LYS   A C    1 
ATOM   2899 O  O    . LYS   A 1 167 ? 21.47071 -19.04974 20.00661  1.000 32.46457  ? 167 LYS   A O    1 
ATOM   2900 C  CB   . LYS   A 1 167 ? 21.89470 -17.28641 17.31048  1.000 25.44115  ? 167 LYS   A CB   1 
ATOM   2901 C  CG   . LYS   A 1 167 ? 21.58781 -17.27148 15.81287  1.000 27.64447  ? 167 LYS   A CG   1 
ATOM   2902 C  CD   . LYS   A 1 167 ? 22.83692 -17.03702 15.03859  1.000 26.78546  ? 167 LYS   A CD   1 
ATOM   2903 C  CE   . LYS   A 1 167 ? 22.58063 -16.94176 13.54953  1.000 35.09821  ? 167 LYS   A CE   1 
ATOM   2904 N  NZ   . LYS   A 1 167 ? 23.84940 -16.68509 12.83122  1.000 32.67377  ? 167 LYS   A NZ   1 
ATOM   2905 H  H    . LYS   A 1 167 ? 19.88097 -15.96227 17.62643  1.000 31.62340  ? 167 LYS   A H    1 
ATOM   2906 H  HA   . LYS   A 1 167 ? 20.34750 -18.50774 17.83686  1.000 35.35795  ? 167 LYS   A HA   1 
ATOM   2907 H  HB2  . LYS   A 1 167 ? 22.18189 -16.39459 17.56166  1.000 30.54366  ? 167 LYS   A HB2  1 
ATOM   2908 H  HB3  . LYS   A 1 167 ? 22.61389 -17.92038 17.45793  1.000 30.54366  ? 167 LYS   A HB3  1 
ATOM   2909 H  HG2  . LYS   A 1 167 ? 21.21320 -18.12595 15.54747  1.000 33.18763  ? 167 LYS   A HG2  1 
ATOM   2910 H  HG3  . LYS   A 1 167 ? 20.96073 -16.55843 15.61483  1.000 33.18763  ? 167 LYS   A HG3  1 
ATOM   2911 H  HD2  . LYS   A 1 167 ? 23.23972 -16.20378 15.32905  1.000 32.15682  ? 167 LYS   A HD2  1 
ATOM   2912 H  HD3  . LYS   A 1 167 ? 23.44964 -17.77308 15.19252  1.000 32.15682  ? 167 LYS   A HD3  1 
ATOM   2913 H  HE2  . LYS   A 1 167 ? 22.20494 -17.77653 13.22874  1.000 42.13213  ? 167 LYS   A HE2  1 
ATOM   2914 H  HE3  . LYS   A 1 167 ? 21.96810 -16.21145 13.36964  1.000 42.13213  ? 167 LYS   A HE3  1 
ATOM   2915 H  HZ1  . LYS   A 1 167 ? 23.70253 -16.65892 11.95382  1.000 39.22279  ? 167 LYS   A HZ1  1 
ATOM   2916 H  HZ2  . LYS   A 1 167 ? 24.19341 -15.90608 13.08986  1.000 39.22279  ? 167 LYS   A HZ2  1 
ATOM   2917 H  HZ3  . LYS   A 1 167 ? 24.43489 -17.33196 13.00690  1.000 39.22279  ? 167 LYS   A HZ3  1 
ATOM   2918 N  N    . ALA   A 1 168 ? 21.30203 -16.84230 20.38520  1.000 25.86172  ? 168 ALA   A N    1 
ATOM   2919 C  CA   . ALA   A 1 168 ? 21.67499 -16.95437 21.79771  1.000 28.26712  ? 168 ALA   A CA   1 
ATOM   2920 C  C    . ALA   A 1 168 ? 20.51074 -17.42385 22.67036  1.000 28.23509  ? 168 ALA   A C    1 
ATOM   2921 O  O    . ALA   A 1 168 ? 20.73666 -17.83585 23.81271  1.000 34.58214  ? 168 ALA   A O    1 
ATOM   2922 C  CB   . ALA   A 1 168 ? 22.18631 -15.61100 22.30591  1.000 27.65747  ? 168 ALA   A CB   1 
ATOM   2923 H  H    . ALA   A 1 168 ? 21.17311 -16.03421 20.12069  1.000 31.04834  ? 168 ALA   A H    1 
ATOM   2924 H  HA   . ALA   A 1 168 ? 22.39329 -17.60040 21.88479  1.000 33.93481  ? 168 ALA   A HA   1 
ATOM   2925 H  HB1  . ALA   A 1 168 ? 22.45821 -15.70647 23.23211  1.000 33.20324  ? 168 ALA   A HB1  1 
ATOM   2926 H  HB2  . ALA   A 1 168 ? 22.94357 -15.33639 21.76549  1.000 33.20324  ? 168 ALA   A HB2  1 
ATOM   2927 H  HB3  . ALA   A 1 168 ? 21.47489 -14.95534 22.23592  1.000 33.20324  ? 168 ALA   A HB3  1 
ATOM   2928 N  N    . GLY   A 1 169 ? 19.28335 -17.32944 22.17258  1.000 29.69329  ? 169 GLY   A N    1 
ATOM   2929 C  CA   . GLY   A 1 169 ? 18.12852 -17.80252 22.89061  1.000 34.93436  ? 169 GLY   A CA   1 
ATOM   2930 C  C    . GLY   A 1 169 ? 17.66297 -16.92151 24.01512  1.000 40.37834  ? 169 GLY   A C    1 
ATOM   2931 O  O    . GLY   A 1 169 ? 17.03786 -17.42022 24.94915  1.000 33.50986  ? 169 GLY   A O    1 
ATOM   2932 H  H    . GLY   A 1 169 ? 19.09725 -16.98765 21.40567  1.000 35.64622  ? 169 GLY   A H    1 
ATOM   2933 H  HA2  . GLY   A 1 169 ? 17.39250 -17.89367 22.26542  1.000 41.93550  ? 169 GLY   A HA2  1 
ATOM   2934 H  HA3  . GLY   A 1 169 ? 18.33382 -18.67314 23.26582  1.000 41.93550  ? 169 GLY   A HA3  1 
ATOM   2935 N  N    . VAL   A 1 170 ? 17.94191 -15.61351 23.95830  1.000 28.54411  ? 170 VAL   A N    1 
ATOM   2936 C  CA   . VAL   A 1 170 ? 17.58285 -14.70511 25.04334  1.000 32.82876  ? 170 VAL   A CA   1 
ATOM   2937 C  C    . VAL   A 1 170 ? 17.03588 -13.41440 24.45255  1.000 36.57632  ? 170 VAL   A C    1 
ATOM   2938 O  O    . VAL   A 1 170 ? 17.27669 -13.08496 23.29235  1.000 31.72528  ? 170 VAL   A O    1 
ATOM   2939 C  CB   . VAL   A 1 170 ? 18.77889 -14.40158 25.96223  1.000 37.08160  ? 170 VAL   A CB   1 
ATOM   2940 C  CG1  . VAL   A 1 170 ? 19.32439 -15.68152 26.56905  1.000 32.86656  ? 170 VAL   A CG1  1 
ATOM   2941 C  CG2  . VAL   A 1 170 ? 19.87023 -13.67876 25.19769  1.000 32.09611  ? 170 VAL   A CG2  1 
ATOM   2942 H  H    . VAL   A 1 170 ? 18.33968 -15.23226 23.29798  1.000 34.26721  ? 170 VAL   A H    1 
ATOM   2943 H  HA   . VAL   A 1 170 ? 16.88094 -15.11071 25.57598  1.000 39.40878  ? 170 VAL   A HA   1 
ATOM   2944 H  HB   . VAL   A 1 170 ? 18.47656 -13.82561 26.68179  1.000 44.51219  ? 170 VAL   A HB   1 
ATOM   2945 H  HG11 . VAL   A 1 170 ? 20.03370 -15.45842 27.19196  1.000 39.45414  ? 170 VAL   A HG11 1 
ATOM   2946 H  HG12 . VAL   A 1 170 ? 18.60786 -16.14081 27.03438  1.000 39.45414  ? 170 VAL   A HG12 1 
ATOM   2947 H  HG13 . VAL   A 1 170 ? 19.67210 -16.24422 25.85957  1.000 39.45414  ? 170 VAL   A HG13 1 
ATOM   2948 H  HG21 . VAL   A 1 170 ? 20.67109 -13.64768 25.74410  1.000 38.52960  ? 170 VAL   A HG21 1 
ATOM   2949 H  HG22 . VAL   A 1 170 ? 20.05003 -14.15888 24.37425  1.000 38.52960  ? 170 VAL   A HG22 1 
ATOM   2950 H  HG23 . VAL   A 1 170 ? 19.57162 -12.77797 24.99692  1.000 38.52960  ? 170 VAL   A HG23 1 
ATOM   2951 N  N    . LYS   A 1 171 ? 16.29044 -12.67456 25.27298  1.000 34.86564  ? 171 LYS   A N    1 
ATOM   2952 C  CA   . LYS   A 1 171 ? 15.83586 -11.36241 24.84349  1.000 43.66943  ? 171 LYS   A CA   1 
ATOM   2953 C  C    . LYS   A 1 171 ? 16.94266 -10.33211 25.07865  1.000 25.68738  ? 171 LYS   A C    1 
ATOM   2954 O  O    . LYS   A 1 171 ? 17.92554 -10.59306 25.77587  1.000 29.44864  ? 171 LYS   A O    1 
ATOM   2955 C  CB   . LYS   A 1 171 ? 14.55683 -10.95427 25.56866  1.000 55.26886  ? 171 LYS   A CB   1 
ATOM   2956 C  CG   . LYS   A 1 171 ? 13.27148 -11.58117 24.99246  1.000 74.68139  ? 171 LYS   A CG   1 
ATOM   2957 C  CD   . LYS   A 1 171 ? 13.22608 -11.55310 23.45355  1.000 106.64645 ? 171 LYS   A CD   1 
ATOM   2958 C  CE   . LYS   A 1 171 ? 11.94370 -12.16959 22.89645  1.000 98.12026  ? 171 LYS   A CE   1 
ATOM   2959 N  NZ   . LYS   A 1 171 ? 11.43592 -13.29853 23.73849  1.000 63.52617  ? 171 LYS   A NZ   1 
ATOM   2960 H  H    . LYS   A 1 171 ? 16.04286 -12.90789 26.06283  1.000 41.85304  ? 171 LYS   A H    1 
ATOM   2961 H  HA   . LYS   A 1 171 ? 15.62916 -11.39026 23.89618  1.000 52.41759  ? 171 LYS   A HA   1 
ATOM   2962 H  HB2  . LYS   A 1 171 ? 14.62645 -11.22794 26.49665  1.000 66.33690  ? 171 LYS   A HB2  1 
ATOM   2963 H  HB3  . LYS   A 1 171 ? 14.46374 -9.99035  25.51313  1.000 66.33690  ? 171 LYS   A HB3  1 
ATOM   2964 H  HG2  . LYS   A 1 171 ? 13.21759 -12.50729 25.27584  1.000 89.63194  ? 171 LYS   A HG2  1 
ATOM   2965 H  HG3  . LYS   A 1 171 ? 12.50431 -11.08797 25.32278  1.000 89.63194  ? 171 LYS   A HG3  1 
ATOM   2966 H  HD2  . LYS   A 1 171 ? 13.27352 -10.63269 23.15104  1.000 127.99001 ? 171 LYS   A HD2  1 
ATOM   2967 H  HD3  . LYS   A 1 171 ? 13.97821 -12.05629 23.10428  1.000 127.99001 ? 171 LYS   A HD3  1 
ATOM   2968 H  HE2  . LYS   A 1 171 ? 11.25427 -11.48824 22.85989  1.000 117.75859 ? 171 LYS   A HE2  1 
ATOM   2969 H  HE3  . LYS   A 1 171 ? 12.11792 -12.51337 22.00630  1.000 117.75859 ? 171 LYS   A HE3  1 
ATOM   2970 H  HZ1  . LYS   A 1 171 ? 10.74887 -13.69454 23.33446  1.000 76.24567  ? 171 LYS   A HZ1  1 
ATOM   2971 H  HZ2  . LYS   A 1 171 ? 12.08132 -13.89816 23.86497  1.000 76.24567  ? 171 LYS   A HZ2  1 
ATOM   2972 H  HZ3  . LYS   A 1 171 ? 11.16783 -12.99150 24.52967  1.000 76.24567  ? 171 LYS   A HZ3  1 
ATOM   2973 N  N    . GLY   A 1 172 ? 16.77584 -9.16495  24.45753  1.000 33.35481  ? 172 GLY   A N    1 
ATOM   2974 C  CA   . GLY   A 1 172 ? 17.84240 -8.18139  24.45058  1.000 38.99759  ? 172 GLY   A CA   1 
ATOM   2975 C  C    . GLY   A 1 172 ? 18.23430 -7.72478  25.83660  1.000 41.17561  ? 172 GLY   A C    1 
ATOM   2976 O  O    . GLY   A 1 172 ? 19.39587 -7.36918  26.07052  1.000 33.82111  ? 172 GLY   A O    1 
ATOM   2977 H  H    . GLY   A 1 172 ? 16.06327 -8.92542  24.03984  1.000 40.04004  ? 172 GLY   A H    1 
ATOM   2978 H  HA2  . GLY   A 1 172 ? 18.62546 -8.56395  24.02471  1.000 46.81138  ? 172 GLY   A HA2  1 
ATOM   2979 H  HA3  . GLY   A 1 172 ? 17.55584 -7.40462  23.94521  1.000 46.81138  ? 172 GLY   A HA3  1 
ATOM   2980 N  N    . GLU   A 1 173 ? 17.27837 -7.73527  26.77694  1.000 40.67193  ? 173 GLU   A N    1 
ATOM   2981 C  CA   . GLU   A 1 173 ? 17.57178 -7.36253  28.15472  1.000 37.26599  ? 173 GLU   A CA   1 
ATOM   2982 C  C    . GLU   A 1 173 ? 18.67181 -8.20974  28.76329  1.000 37.41543  ? 173 GLU   A C    1 
ATOM   2983 O  O    . GLU   A 1 173 ? 19.31877 -7.77850  29.71911  1.000 41.81749  ? 173 GLU   A O    1 
ATOM   2984 C  CB   . GLU   A 1 173 ? 16.30401 -7.49666  29.02583  1.000 47.82452  ? 173 GLU   A CB   1 
ATOM   2985 C  CG   . GLU   A 1 173 ? 15.06658 -6.73216  28.53772  1.000 52.79854  ? 173 GLU   A CG   1 
ATOM   2986 C  CD   . GLU   A 1 173 ? 14.40199 -7.36605  27.31832  1.000 64.66835  ? 173 GLU   A CD   1 
ATOM   2987 O  OE1  . GLU   A 1 173 ? 14.41154 -6.73521  26.24308  1.000 86.37648  ? 173 GLU   A OE1  1 
ATOM   2988 O  OE2  . GLU   A 1 173 ? 13.89615 -8.50675  27.43242  1.000 94.69465  ? 173 GLU   A OE2  1 
ATOM   2989 H  H    . GLU   A 1 173 ? 16.45837 -7.95401  26.63778  1.000 48.82058  ? 173 GLU   A H    1 
ATOM   2990 H  HA   . GLU   A 1 173 ? 17.85771 -6.43563  28.15848  1.000 44.73346  ? 173 GLU   A HA   1 
ATOM   2991 H  HB2  . GLU   A 1 173 ? 16.06278 -8.43529  29.06691  1.000 57.40369  ? 173 GLU   A HB2  1 
ATOM   2992 H  HB3  . GLU   A 1 173 ? 16.51123 -7.16816  29.91468  1.000 57.40369  ? 173 GLU   A HB3  1 
ATOM   2993 H  HG2  . GLU   A 1 173 ? 14.41181 -6.70652  29.25293  1.000 63.37252  ? 173 GLU   A HG2  1 
ATOM   2994 H  HG3  . GLU   A 1 173 ? 15.33028 -5.83030  28.29685  1.000 63.37252  ? 173 GLU   A HG3  1 
ATOM   2995 N  N    . LYS   A 1 174 ? 18.89057 -9.42481  28.24285  1.000 33.95009  ? 174 LYS   A N    1 
ATOM   2996 C  CA   . LYS   A 1 174 ? 19.89089 -10.32660 28.77500  1.000 32.47679  ? 174 LYS   A CA   1 
ATOM   2997 C  C    . LYS   A 1 174 ? 21.23165 -10.23563 28.04791  1.000 30.14514  ? 174 LYS   A C    1 
ATOM   2998 O  O    . LYS   A 1 174 ? 22.06650 -11.12989 28.21414  1.000 33.31667  ? 174 LYS   A O    1 
ATOM   2999 C  CB   . LYS   A 1 174 ? 19.38218 -11.77448 28.69568  1.000 36.85492  ? 174 LYS   A CB   1 
ATOM   3000 C  CG   . LYS   A 1 174 ? 18.00965 -12.00552 29.31069  1.000 40.42398  ? 174 LYS   A CG   1 
ATOM   3001 C  CD   . LYS   A 1 174 ? 18.00137 -11.69190 30.79606  1.000 42.40456  ? 174 LYS   A CD   1 
ATOM   3002 C  CE   . LYS   A 1 174 ? 16.68500 -12.12744 31.43881  1.000 63.87733  ? 174 LYS   A CE   1 
ATOM   3003 N  NZ   . LYS   A 1 174 ? 16.66763 -11.85693 32.91342  1.000 51.65340  ? 174 LYS   A NZ   1 
ATOM   3004 H  H    . LYS   A 1 174 ? 18.45960 -9.74423  27.57066  1.000 40.75438  ? 174 LYS   A H    1 
ATOM   3005 H  HA   . LYS   A 1 174 ? 20.03763 -10.09441 29.70530  1.000 38.98642  ? 174 LYS   A HA   1 
ATOM   3006 H  HB2  . LYS   A 1 174 ? 19.32988 -12.03121 27.76173  1.000 44.24018  ? 174 LYS   A HB2  1 
ATOM   3007 H  HB3  . LYS   A 1 174 ? 20.01071 -12.34716 29.16246  1.000 44.24018  ? 174 LYS   A HB3  1 
ATOM   3008 H  HG2  . LYS   A 1 174 ? 17.36184 -11.43008 28.87467  1.000 48.52304  ? 174 LYS   A HG2  1 
ATOM   3009 H  HG3  . LYS   A 1 174 ? 17.75860 -12.93526 29.19468  1.000 48.52304  ? 174 LYS   A HG3  1 
ATOM   3010 H  HD2  . LYS   A 1 174 ? 18.72727 -12.16618 31.23084  1.000 50.89974  ? 174 LYS   A HD2  1 
ATOM   3011 H  HD3  . LYS   A 1 174 ? 18.10501 -10.73617 30.92544  1.000 50.89974  ? 174 LYS   A HD3  1 
ATOM   3012 H  HE2  . LYS   A 1 174 ? 15.95307 -11.63806 31.03177  1.000 76.66706  ? 174 LYS   A HE2  1 
ATOM   3013 H  HE3  . LYS   A 1 174 ? 16.56289 -13.08017 31.30351  1.000 76.66706  ? 174 LYS   A HE3  1 
ATOM   3014 H  HZ1  . LYS   A 1 174 ? 15.88483 -12.10211 33.25868  1.000 61.99835  ? 174 LYS   A HZ1  1 
ATOM   3015 H  HZ2  . LYS   A 1 174 ? 17.31653 -12.31525 33.31464  1.000 61.99835  ? 174 LYS   A HZ2  1 
ATOM   3016 H  HZ3  . LYS   A 1 174 ? 16.79096 -10.98866 33.06509  1.000 61.99835  ? 174 LYS   A HZ3  1 
ATOM   3017 N  N    . ALA   A 1 175 ? 21.44947 -9.19893  27.24249  1.000 32.44268  ? 175 ALA   A N    1 
ATOM   3018 C  CA   . ALA   A 1 175 ? 22.60563 -9.16480  26.35021  1.000 32.09566  ? 175 ALA   A CA   1 
ATOM   3019 C  C    . ALA   A 1 175 ? 23.27472 -7.79487  26.33776  1.000 33.49480  ? 175 ALA   A C    1 
ATOM   3020 O  O    . ALA   A 1 175 ? 22.62149 -6.75793  26.48674  1.000 34.98727  ? 175 ALA   A O    1 
ATOM   3021 C  CB   . ALA   A 1 175 ? 22.19303 -9.51444  24.90475  1.000 33.93339  ? 175 ALA   A CB   1 
ATOM   3022 H  H    . ALA   A 1 175 ? 20.94342 -8.50523  27.19468  1.000 38.94549  ? 175 ALA   A H    1 
ATOM   3023 H  HA   . ALA   A 1 175 ? 23.25687 -9.80038  26.68610  1.000 38.52906  ? 175 ALA   A HA   1 
ATOM   3024 H  HB1  . ALA   A 1 175 ? 22.97766 -9.48071  24.33544  1.000 40.73433  ? 175 ALA   A HB1  1 
ATOM   3025 H  HB2  . ALA   A 1 175 ? 21.81313 -10.40686 24.89187  1.000 40.73433  ? 175 ALA   A HB2  1 
ATOM   3026 H  HB3  . ALA   A 1 175 ? 21.53501 -8.87039  24.59960  1.000 40.73433  ? 175 ALA   A HB3  1 
ATOM   3027 N  N    . VAL   A 1 176 ? 24.59498 -7.81019  26.15551  1.000 31.52549  ? 176 VAL   A N    1 
ATOM   3028 C  CA   A VAL   A 1 176 ? 25.35378 -6.58756  25.93331  0.460 40.38447  ? 176 VAL   A CA   1 
ATOM   3029 C  CA   B VAL   A 1 176 ? 25.40170 -6.61030  25.94865  0.540 40.45344  ? 176 VAL   A CA   1 
ATOM   3030 C  C    . VAL   A 1 176 ? 25.92222 -6.61606  24.51732  1.000 35.95509  ? 176 VAL   A C    1 
ATOM   3031 O  O    . VAL   A 1 176 ? 26.22095 -7.67727  23.94927  1.000 36.02810  ? 176 VAL   A O    1 
ATOM   3032 C  CB   A VAL   A 1 176 ? 26.47812 -6.38282  26.96973  0.460 33.22061  ? 176 VAL   A CB   1 
ATOM   3033 C  CB   B VAL   A 1 176 ? 26.56850 -6.55736  26.95574  0.540 33.61835  ? 176 VAL   A CB   1 
ATOM   3034 C  CG1  A VAL   A 1 176 ? 25.98205 -6.70392  28.37489  0.460 43.67240  ? 176 VAL   A CG1  1 
ATOM   3035 C  CG1  B VAL   A 1 176 ? 27.72657 -5.73003  26.41252  0.540 27.93204  ? 176 VAL   A CG1  1 
ATOM   3036 C  CG2  A VAL   A 1 176 ? 27.70653 -7.20659  26.63472  0.460 24.58568  ? 176 VAL   A CG2  1 
ATOM   3037 C  CG2  B VAL   A 1 176 ? 26.10164 -6.00065  28.29330  0.540 34.12166  ? 176 VAL   A CG2  1 
ATOM   3038 H  H    A VAL   A 1 176 ? 25.07421 -8.52429  26.15693  0.460 37.84486  ? 176 VAL   A H    1 
ATOM   3039 H  H    B VAL   A 1 176 ? 25.06282 -8.53176  26.14748  0.540 37.84486  ? 176 VAL   A H    1 
ATOM   3040 H  HA   A VAL   A 1 176 ? 24.74793 -5.83399  26.01063  0.460 48.47564  ? 176 VAL   A HA   1 
ATOM   3041 H  HA   B VAL   A 1 176 ? 24.85257 -5.81916  26.06464  0.540 48.55840  ? 176 VAL   A HA   1 
ATOM   3042 H  HB   A VAL   A 1 176 ? 26.74022 -5.44925  26.94393  0.460 39.87900  ? 176 VAL   A HB   1 
ATOM   3043 H  HB   B VAL   A 1 176 ? 26.88765 -7.46257  27.09586  0.540 40.35629  ? 176 VAL   A HB   1 
ATOM   3044 H  HG11 A VAL   A 1 176 ? 26.70446 -6.55869  29.00571  0.460 52.42115  ? 176 VAL   A HG11 1 
ATOM   3045 H  HG11 B VAL   A 1 176 ? 28.35146 -5.55057  27.13239  0.540 33.53272  ? 176 VAL   A HG11 1 
ATOM   3046 H  HG12 A VAL   A 1 176 ? 25.23567 -6.12184  28.58700  0.460 52.42115  ? 176 VAL   A HG12 1 
ATOM   3047 H  HG12 B VAL   A 1 176 ? 28.16823 -6.22939  25.70791  0.540 33.53272  ? 176 VAL   A HG12 1 
ATOM   3048 H  HG13 A VAL   A 1 176 ? 25.69772 -7.63082  28.40529  0.460 52.42115  ? 176 VAL   A HG13 1 
ATOM   3049 H  HG13 B VAL   A 1 176 ? 27.38024 -4.89559  26.05943  0.540 33.53272  ? 176 VAL   A HG13 1 
ATOM   3050 H  HG21 A VAL   A 1 176 ? 28.29041 -7.23211  27.40889  0.460 29.51708  ? 176 VAL   A HG21 1 
ATOM   3051 H  HG21 B VAL   A 1 176 ? 26.72423 -6.27564  28.98444  0.540 40.96027  ? 176 VAL   A HG21 1 
ATOM   3052 H  HG22 A VAL   A 1 176 ? 27.42923 -8.10592  26.39977  0.460 29.51708  ? 176 VAL   A HG22 1 
ATOM   3053 H  HG22 B VAL   A 1 176 ? 26.07324 -5.03255  28.23983  0.540 40.96027  ? 176 VAL   A HG22 1 
ATOM   3054 H  HG23 A VAL   A 1 176 ? 28.16737 -6.79637  25.88623  0.460 29.51708  ? 176 VAL   A HG23 1 
ATOM   3055 H  HG23 B VAL   A 1 176 ? 25.21689 -6.34728  28.48814  0.540 40.96027  ? 176 VAL   A HG23 1 
ATOM   3056 N  N    . TYR   A 1 177 ? 26.04477 -5.42951  23.92961  1.000 35.19145  ? 177 TYR   A N    1 
ATOM   3057 C  CA   . TYR   A 1 177 ? 26.62948 -5.27680  22.58993  1.000 33.62484  ? 177 TYR   A CA   1 
ATOM   3058 C  C    . TYR   A 1 177 ? 27.79076 -4.29298  22.67076  1.000 39.51353  ? 177 TYR   A C    1 
ATOM   3059 O  O    . TYR   A 1 177 ? 27.61919 -3.15990  23.13827  1.000 36.80168  ? 177 TYR   A O    1 
ATOM   3060 C  CB   . TYR   A 1 177 ? 25.60160 -4.79664  21.57428  1.000 39.22932  ? 177 TYR   A CB   1 
ATOM   3061 C  CG   . TYR   A 1 177 ? 26.21756 -4.47739  20.22940  1.000 52.89081  ? 177 TYR   A CG   1 
ATOM   3062 C  CD1  . TYR   A 1 177 ? 26.73424 -5.47717  19.42160  1.000 43.50140  ? 177 TYR   A CD1  1 
ATOM   3063 C  CD2  . TYR   A 1 177 ? 26.29044 -3.18221  19.77000  1.000 52.79907  ? 177 TYR   A CD2  1 
ATOM   3064 C  CE1  . TYR   A 1 177 ? 27.30062 -5.18523  18.18565  1.000 39.39691  ? 177 TYR   A CE1  1 
ATOM   3065 C  CE2  . TYR   A 1 177 ? 26.84968 -2.87168  18.53458  1.000 51.78104  ? 177 TYR   A CE2  1 
ATOM   3066 C  CZ   . TYR   A 1 177 ? 27.35557 -3.88344  17.75044  1.000 51.67821  ? 177 TYR   A CZ   1 
ATOM   3067 O  OH   . TYR   A 1 177 ? 27.92327 -3.59576  16.53088  1.000 53.43289  ? 177 TYR   A OH   1 
ATOM   3068 H  H    . TYR   A 1 177 ? 25.79525 -4.68808  24.28685  1.000 42.24401  ? 177 TYR   A H    1 
ATOM   3069 H  HA   . TYR   A 1 177 ? 26.96556 -6.13758  22.29494  1.000 40.36408  ? 177 TYR   A HA   1 
ATOM   3070 H  HB2  . TYR   A 1 177 ? 24.93746 -5.49148  21.44377  1.000 47.08946  ? 177 TYR   A HB2  1 
ATOM   3071 H  HB3  . TYR   A 1 177 ? 25.17765 -3.99133  21.90989  1.000 47.08946  ? 177 TYR   A HB3  1 
ATOM   3072 H  HD1  . TYR   A 1 177 ? 26.70169 -6.36027  19.71137  1.000 52.21595  ? 177 TYR   A HD1  1 
ATOM   3073 H  HD2  . TYR   A 1 177 ? 25.95642 -2.49515  20.30036  1.000 63.37315  ? 177 TYR   A HD2  1 
ATOM   3074 H  HE1  . TYR   A 1 177 ? 27.64114 -5.86913  17.65535  1.000 47.29056  ? 177 TYR   A HE1  1 
ATOM   3075 H  HE2  . TYR   A 1 177 ? 26.88137 -1.98961  18.24157  1.000 62.15152  ? 177 TYR   A HE2  1 
ATOM   3076 H  HH   . TYR   A 1 177 ? 27.85652 -2.77410  16.36957  1.000 64.13374  ? 177 TYR   A HH   1 
ATOM   3077 N  N    . VAL   A 1 178 ? 28.96296 -4.73065  22.22924  1.000 34.35197  ? 178 VAL   A N    1 
ATOM   3078 C  CA   . VAL   A 1 178 ? 30.17629 -3.92771  22.22449  1.000 31.63680  ? 178 VAL   A CA   1 
ATOM   3079 C  C    . VAL   A 1 178 ? 30.43912 -3.47284  20.79863  1.000 40.48160  ? 178 VAL   A C    1 
ATOM   3080 O  O    . VAL   A 1 178 ? 30.69832 -4.30362  19.92584  1.000 33.09822  ? 178 VAL   A O    1 
ATOM   3081 C  CB   . VAL   A 1 178 ? 31.36993 -4.73709  22.76045  1.000 33.33938  ? 178 VAL   A CB   1 
ATOM   3082 C  CG1  . VAL   A 1 178 ? 32.61494 -3.85277  22.83886  1.000 36.29447  ? 178 VAL   A CG1  1 
ATOM   3083 C  CG2  . VAL   A 1 178 ? 31.04014 -5.36012  24.09999  1.000 37.36650  ? 178 VAL   A CG2  1 
ATOM   3084 H  H    . VAL   A 1 178 ? 29.08447 -5.52187  21.91489  1.000 41.23664  ? 178 VAL   A H    1 
ATOM   3085 H  HA   . VAL   A 1 178 ? 30.04721 -3.14355  22.78066  1.000 37.97843  ? 178 VAL   A HA   1 
ATOM   3086 H  HB   . VAL   A 1 178 ? 31.56301 -5.46469  22.14872  1.000 40.02152  ? 178 VAL   A HB   1 
ATOM   3087 H  HG11 . VAL   A 1 178 ? 33.33070 -4.35196  23.26240  1.000 43.56763  ? 178 VAL   A HG11 1 
ATOM   3088 H  HG12 . VAL   A 1 178 ? 32.87703 -3.59608  21.94090  1.000 43.56763  ? 178 VAL   A HG12 1 
ATOM   3089 H  HG13 . VAL   A 1 178 ? 32.40845 -3.06236  23.36185  1.000 43.56763  ? 178 VAL   A HG13 1 
ATOM   3090 H  HG21 . VAL   A 1 178 ? 31.84051 -5.77071  24.46294  1.000 44.85408  ? 178 VAL   A HG21 1 
ATOM   3091 H  HG22 . VAL   A 1 178 ? 30.72205 -4.66793  24.70048  1.000 44.85408  ? 178 VAL   A HG22 1 
ATOM   3092 H  HG23 . VAL   A 1 178 ? 30.35145 -6.03167  23.97496  1.000 44.85408  ? 178 VAL   A HG23 1 
ATOM   3093 N  N    . GLY   A 1 179 ? 30.36874 -2.16076  20.55894  1.000 34.47629  ? 179 GLY   A N    1 
ATOM   3094 C  CA   . GLY   A 1 179 ? 30.61020 -1.60324  19.24440  1.000 45.09306  ? 179 GLY   A CA   1 
ATOM   3095 C  C    . GLY   A 1 179 ? 31.44017 -0.33260  19.33094  1.000 43.98320  ? 179 GLY   A C    1 
ATOM   3096 O  O    . GLY   A 1 179 ? 31.78605 0.12941   20.41144  1.000 40.72515  ? 179 GLY   A O    1 
ATOM   3097 H  H    . GLY   A 1 179 ? 30.17945 -1.57127  21.15583  1.000 41.38582  ? 179 GLY   A H    1 
ATOM   3098 H  HA2  . GLY   A 1 179 ? 31.08646 -2.24859  18.69887  1.000 54.12595  ? 179 GLY   A HA2  1 
ATOM   3099 H  HA3  . GLY   A 1 179 ? 29.76425 -1.39310  18.81882  1.000 54.12595  ? 179 GLY   A HA3  1 
ATOM   3100 N  N    . ASP   A 1 180 ? 31.76542 0.21824   18.16635  1.000 53.87878  ? 180 ASP   A N    1 
ATOM   3101 C  CA   . ASP   A 1 180 ? 32.49672 1.47886   18.10802  1.000 67.16253  ? 180 ASP   A CA   1 
ATOM   3102 C  C    . ASP   A 1 180 ? 31.73404 2.57418   17.37619  1.000 71.30513  ? 180 ASP   A C    1 
ATOM   3103 O  O    . ASP   A 1 180 ? 32.19613 3.72092   17.35872  1.000 70.28109  ? 180 ASP   A O    1 
ATOM   3104 C  CB   . ASP   A 1 180 ? 33.87625 1.27602   17.45375  1.000 62.43753  ? 180 ASP   A CB   1 
ATOM   3105 C  CG   . ASP   A 1 180 ? 33.81512 1.25471   15.93886  1.000 71.86926  ? 180 ASP   A CG   1 
ATOM   3106 O  OD1  . ASP   A 1 180 ? 32.72743 0.99754   15.37319  1.000 67.47516  ? 180 ASP   A OD1  1 
ATOM   3107 O  OD2  . ASP   A 1 180 ? 34.86926 1.49477   15.31094  1.000 80.36895  ? 180 ASP   A OD2  1 
ATOM   3108 H  H    . ASP   A 1 180 ? 31.57427 -0.11802  17.39824  1.000 64.66881  ? 180 ASP   A H    1 
ATOM   3109 H  HA   . ASP   A 1 180 ? 32.66287 1.79182   19.01099  1.000 80.60930  ? 180 ASP   A HA   1 
ATOM   3110 H  HB2  . ASP   A 1 180 ? 34.46108 2.00292   17.71926  1.000 74.93931  ? 180 ASP   A HB2  1 
ATOM   3111 H  HB3  . ASP   A 1 180 ? 34.24430 0.42892   17.75015  1.000 74.93931  ? 180 ASP   A HB3  1 
ATOM   3112 N  N    . ASN   A 1 181 ? 30.59419 2.25875   16.77652  1.000 74.69048  ? 181 ASN   A N    1 
ATOM   3113 C  CA   . ASN   A 1 181 ? 29.71668 3.25063   16.15492  1.000 76.75931  ? 181 ASN   A CA   1 
ATOM   3114 C  C    . ASN   A 1 181 ? 28.37120 3.17631   16.86062  1.000 100.49437 ? 181 ASN   A C    1 
ATOM   3115 O  O    . ASN   A 1 181 ? 27.64343 2.17743   16.69696  1.000 115.61776 ? 181 ASN   A O    1 
ATOM   3116 C  CB   . ASN   A 1 181 ? 29.55900 2.98776   14.65733  1.000 91.60519  ? 181 ASN   A CB   1 
ATOM   3117 H  H    . ASN   A 1 181 ? 30.29559 1.45477   16.71289  1.000 89.64285  ? 181 ASN   A H    1 
ATOM   3118 H  HA   . ASN   A 1 181 ? 30.09006 4.14070   16.25114  1.000 92.12544  ? 181 ASN   A HA   1 
ATOM   3119 N  N    . PRO   A 1 182 ? 27.99057 4.17874   17.65536  1.000 107.64885 ? 182 PRO   A N    1 
ATOM   3120 C  CA   . PRO   A 1 182 ? 26.76797 4.04708   18.46190  1.000 117.66266 ? 182 PRO   A CA   1 
ATOM   3121 C  C    . PRO   A 1 182 ? 25.48158 4.36443   17.71896  1.000 124.45377 ? 182 PRO   A C    1 
ATOM   3122 O  O    . PRO   A 1 182 ? 24.40047 4.09766   18.26450  1.000 92.26366  ? 182 PRO   A O    1 
ATOM   3123 C  CB   . PRO   A 1 182 ? 27.00126 5.04839   19.60516  1.000 104.96073 ? 182 PRO   A CB   1 
ATOM   3124 C  CG   . PRO   A 1 182 ? 27.85935 6.11097   18.98710  1.000 109.10267 ? 182 PRO   A CG   1 
ATOM   3125 C  CD   . PRO   A 1 182 ? 28.70542 5.44518   17.91652  1.000 72.26908  ? 182 PRO   A CD   1 
ATOM   3126 H  HA   . PRO   A 1 182 ? 26.70658 3.14958   18.82470  1.000 141.20946 ? 182 PRO   A HA   1 
ATOM   3127 H  HB2  . PRO   A 1 182 ? 26.15494 5.41306   19.90792  1.000 125.96715 ? 182 PRO   A HB2  1 
ATOM   3128 H  HB3  . PRO   A 1 182 ? 27.45783 4.61356   20.34229  1.000 125.96715 ? 182 PRO   A HB3  1 
ATOM   3129 H  HG2  . PRO   A 1 182 ? 27.29240 6.79290   18.59412  1.000 130.93748 ? 182 PRO   A HG2  1 
ATOM   3130 H  HG3  . PRO   A 1 182 ? 28.42573 6.50338   19.66983  1.000 130.93748 ? 182 PRO   A HG3  1 
ATOM   3131 H  HD2  . PRO   A 1 182 ? 28.74217 5.99200   17.11618  1.000 86.73716  ? 182 PRO   A HD2  1 
ATOM   3132 H  HD3  . PRO   A 1 182 ? 29.60270 5.27394   18.24281  1.000 86.73716  ? 182 PRO   A HD3  1 
ATOM   3133 N  N    . VAL   A 1 183 ? 25.55249 4.91003   16.50303  1.000 117.54018 ? 183 VAL   A N    1 
ATOM   3134 C  CA   . VAL   A 1 183 ? 24.33641 5.33170   15.81332  1.000 121.73186 ? 183 VAL   A CA   1 
ATOM   3135 C  C    . VAL   A 1 183 ? 23.67212 4.14888   15.11424  1.000 121.36719 ? 183 VAL   A C    1 
ATOM   3136 O  O    . VAL   A 1 183 ? 22.45753 3.94372   15.22985  1.000 95.78080  ? 183 VAL   A O    1 
ATOM   3137 C  CB   . VAL   A 1 183 ? 24.64917 6.48023   14.83290  1.000 119.99172 ? 183 VAL   A CB   1 
ATOM   3138 C  CG1  . VAL   A 1 183 ? 25.45820 5.98602   13.63889  1.000 105.23892 ? 183 VAL   A CG1  1 
ATOM   3139 C  CG2  . VAL   A 1 183 ? 23.35591 7.15148   14.38138  1.000 79.53697  ? 183 VAL   A CG2  1 
ATOM   3140 H  H    . VAL   A 1 183 ? 26.28013 5.04405   16.06465  1.000 141.06249 ? 183 VAL   A H    1 
ATOM   3141 H  HA   . VAL   A 1 183 ? 23.70951 5.66935   16.47202  1.000 146.09250 ? 183 VAL   A HA   1 
ATOM   3142 H  HB   . VAL   A 1 183 ? 25.19243 7.14087   15.29042  1.000 144.00434 ? 183 VAL   A HB   1 
ATOM   3143 H  HG11 . VAL   A 1 183 ? 25.84367 6.74929   13.18091  1.000 126.30097 ? 183 VAL   A HG11 1 
ATOM   3144 H  HG12 . VAL   A 1 183 ? 26.16308 5.39987   13.95587  1.000 126.30097 ? 183 VAL   A HG12 1 
ATOM   3145 H  HG13 . VAL   A 1 183 ? 24.87060 5.50181   13.03792  1.000 126.30097 ? 183 VAL   A HG13 1 
ATOM   3146 H  HG21 . VAL   A 1 183 ? 23.57181 7.87758   13.77552  1.000 95.45864  ? 183 VAL   A HG21 1 
ATOM   3147 H  HG22 . VAL   A 1 183 ? 22.80160 6.49671   13.92871  1.000 95.45864  ? 183 VAL   A HG22 1 
ATOM   3148 H  HG23 . VAL   A 1 183 ? 22.89112 7.49705   15.15948  1.000 95.45864  ? 183 VAL   A HG23 1 
ATOM   3149 N  N    . LYS   A 1 184 ? 24.45167 3.35110   14.37843  1.000 126.07784 ? 184 LYS   A N    1 
ATOM   3150 C  CA   . LYS   A 1 184 ? 23.91454 2.11367   13.82287  1.000 113.22079 ? 184 LYS   A CA   1 
ATOM   3151 C  C    . LYS   A 1 184 ? 23.64669 1.08663   14.91621  1.000 109.09758 ? 184 LYS   A C    1 
ATOM   3152 O  O    . LYS   A 1 184 ? 22.89283 0.13142   14.68911  1.000 72.10293  ? 184 LYS   A O    1 
ATOM   3153 C  CB   . LYS   A 1 184 ? 24.86878 1.54444   12.77698  1.000 98.07738  ? 184 LYS   A CB   1 
ATOM   3154 C  CG   . LYS   A 1 184 ? 25.19252 2.50967   11.63926  1.000 106.38648 ? 184 LYS   A CG   1 
ATOM   3155 C  CD   . LYS   A 1 184 ? 23.93278 3.11836   11.03176  1.000 104.36214 ? 184 LYS   A CD   1 
ATOM   3156 C  CE   . LYS   A 1 184 ? 24.25642 4.01595   9.84309   1.000 99.74429  ? 184 LYS   A CE   1 
ATOM   3157 N  NZ   . LYS   A 1 184 ? 23.05348 4.75410   9.36249   1.000 75.27971  ? 184 LYS   A NZ   1 
ATOM   3158 H  H    . LYS   A 1 184 ? 25.27732 3.50296   14.19178  1.000 151.30767 ? 184 LYS   A H    1 
ATOM   3159 H  HA   . LYS   A 1 184 ? 23.07709 2.30060   13.37051  1.000 135.87922 ? 184 LYS   A HA   1 
ATOM   3160 H  HB2  . LYS   A 1 184 ? 25.70361 1.31119   13.21237  1.000 117.70713 ? 184 LYS   A HB2  1 
ATOM   3161 H  HB3  . LYS   A 1 184 ? 24.46576 0.75314   12.38670  1.000 117.70713 ? 184 LYS   A HB3  1 
ATOM   3162 H  HG2  . LYS   A 1 184 ? 25.74386 3.23149   11.97972  1.000 127.67805 ? 184 LYS   A HG2  1 
ATOM   3163 H  HG3  . LYS   A 1 184 ? 25.66576 2.03218   10.94001  1.000 127.67805 ? 184 LYS   A HG3  1 
ATOM   3164 H  HD2  . LYS   A 1 184 ? 23.34888 2.40700   10.72529  1.000 125.24883 ? 184 LYS   A HD2  1 
ATOM   3165 H  HD3  . LYS   A 1 184 ? 23.48004 3.65349   11.70225  1.000 125.24883 ? 184 LYS   A HD3  1 
ATOM   3166 H  HE2  . LYS   A 1 184 ? 24.92661 4.66598   10.10617  1.000 119.70741 ? 184 LYS   A HE2  1 
ATOM   3167 H  HE3  . LYS   A 1 184 ? 24.59064 3.47180   9.11295   1.000 119.70741 ? 184 LYS   A HE3  1 
ATOM   3168 H  HZ1  . LYS   A 1 184 ? 22.97574 4.66774   8.48011   1.000 90.34992  ? 184 LYS   A HZ1  1 
ATOM   3169 H  HZ2  . LYS   A 1 184 ? 22.32151 4.42849   9.75017   1.000 90.34992  ? 184 LYS   A HZ2  1 
ATOM   3170 H  HZ3  . LYS   A 1 184 ? 23.12640 5.61819   9.56282   1.000 90.34992  ? 184 LYS   A HZ3  1 
ATOM   3171 N  N    . ASP   A 1 185 ? 24.25420 1.26725   16.09153  1.000 113.38098 ? 185 ASP   A N    1 
ATOM   3172 C  CA   . ASP   A 1 185 ? 23.89931 0.48499   17.26904  1.000 95.58887  ? 185 ASP   A CA   1 
ATOM   3173 C  C    . ASP   A 1 185 ? 22.57579 0.96383   17.85604  1.000 125.41761 ? 185 ASP   A C    1 
ATOM   3174 O  O    . ASP   A 1 185 ? 21.62261 0.18682   17.98618  1.000 126.91284 ? 185 ASP   A O    1 
ATOM   3175 C  CB   . ASP   A 1 185 ? 25.02453 0.57943   18.30899  1.000 104.62088 ? 185 ASP   A CB   1 
ATOM   3176 C  CG   . ASP   A 1 185 ? 24.58451 0.13011   19.69465  1.000 138.37687 ? 185 ASP   A CG   1 
ATOM   3177 O  OD1  . ASP   A 1 185 ? 23.79025 0.84158   20.33996  1.000 108.99943 ? 185 ASP   A OD1  1 
ATOM   3178 O  OD2  . ASP   A 1 185 ? 25.01856 -0.91481  20.14452  1.000 125.48290 ? 185 ASP   A OD2  1 
ATOM   3179 H  H    . ASP   A 1 185 ? 24.87917 1.84126   16.23127  1.000 136.07145 ? 185 ASP   A H    1 
ATOM   3180 H  HA   . ASP   A 1 185 ? 23.79858 -0.44701  17.01978  1.000 114.72091 ? 185 ASP   A HA   1 
ATOM   3181 H  HB2  . ASP   A 1 185 ? 25.76117 0.01338   18.02997  1.000 125.55932 ? 185 ASP   A HB2  1 
ATOM   3182 H  HB3  . ASP   A 1 185 ? 25.31993 1.50118   18.37229  1.000 125.55932 ? 185 ASP   A HB3  1 
ATOM   3183 N  N    . ALA   A 1 186 ? 22.50057 2.25240   18.20380  1.000 131.22725 ? 186 ALA   A N    1 
ATOM   3184 C  CA   . ALA   A 1 186 ? 21.31813 2.77387   18.88239  1.000 131.53286 ? 186 ALA   A CA   1 
ATOM   3185 C  C    . ALA   A 1 186 ? 20.06077 2.58680   18.04193  1.000 119.80063 ? 186 ALA   A C    1 
ATOM   3186 O  O    . ALA   A 1 186 ? 19.01299 2.17871   18.55998  1.000 105.51844 ? 186 ALA   A O    1 
ATOM   3187 C  CB   . ALA   A 1 186 ? 21.52384 4.25135   19.22081  1.000 131.02848 ? 186 ALA   A CB   1 
ATOM   3188 H  H    . ALA   A 1 186 ? 23.11451 2.83694   18.05899  1.000 157.48697 ? 186 ALA   A H    1 
ATOM   3189 H  HA   . ALA   A 1 186 ? 21.19398 2.28526   19.71110  1.000 157.85371 ? 186 ALA   A HA   1 
ATOM   3190 H  HB1  . ALA   A 1 186 ? 20.73659 4.58259   19.68061  1.000 157.24844 ? 186 ALA   A HB1  1 
ATOM   3191 H  HB2  . ALA   A 1 186 ? 22.30233 4.33889   19.79281  1.000 157.24844 ? 186 ALA   A HB2  1 
ATOM   3192 H  HB3  . ALA   A 1 186 ? 21.66001 4.74766   18.39859  1.000 157.24844 ? 186 ALA   A HB3  1 
ATOM   3193 N  N    . GLY   A 1 187 ? 20.14405 2.87256   16.74244  1.000 121.58548 ? 187 GLY   A N    1 
ATOM   3194 C  CA   . GLY   A 1 187 ? 18.99542 2.71290   15.86873  1.000 130.68796 ? 187 GLY   A CA   1 
ATOM   3195 C  C    . GLY   A 1 187 ? 18.44688 1.30023   15.79897  1.000 127.01756 ? 187 GLY   A C    1 
ATOM   3196 O  O    . GLY   A 1 187 ? 17.37024 1.10180   15.21888  1.000 88.41504  ? 187 GLY   A O    1 
ATOM   3197 H  H    . GLY   A 1 187 ? 20.85315 3.15881   16.34894  1.000 145.91685 ? 187 GLY   A H    1 
ATOM   3198 H  HA2  . GLY   A 1 187 ? 18.28318 3.29273   16.18085  1.000 156.83982 ? 187 GLY   A HA2  1 
ATOM   3199 H  HA3  . GLY   A 1 187 ? 19.24766 2.97800   14.97040  1.000 156.83982 ? 187 GLY   A HA3  1 
ATOM   3200 N  N    . GLY   A 1 188 ? 19.15278 0.32352   16.36899  1.000 109.43023 ? 188 GLY   A N    1 
ATOM   3201 C  CA   . GLY   A 1 188 ? 18.69843 -1.05058  16.35108  1.000 88.25905  ? 188 GLY   A CA   1 
ATOM   3202 C  C    . GLY   A 1 188 ? 18.63889 -1.70437  17.71874  1.000 107.77396 ? 188 GLY   A C    1 
ATOM   3203 O  O    . GLY   A 1 188 ? 17.56682 -2.13132  18.16332  1.000 91.05699  ? 188 GLY   A O    1 
ATOM   3204 H  H    . GLY   A 1 188 ? 19.90277 0.43910   16.77366  1.000 131.33055 ? 188 GLY   A H    1 
ATOM   3205 H  HA2  . GLY   A 1 188 ? 17.80827 -1.08163  15.96696  1.000 105.92513 ? 188 GLY   A HA2  1 
ATOM   3206 H  HA3  . GLY   A 1 188 ? 19.29977 -1.57259  15.79720  1.000 105.92513 ? 188 GLY   A HA3  1 
ATOM   3207 N  N    . SER   A 1 189 ? 19.78443 -1.77831  18.40344  1.000 77.74803  ? 189 SER   A N    1 
ATOM   3208 C  CA   . SER   A 1 189 ? 19.86329 -2.56738  19.62901  1.000 84.68807  ? 189 SER   A CA   1 
ATOM   3209 C  C    . SER   A 1 189 ? 19.12437 -1.91427  20.79232  1.000 97.05413  ? 189 SER   A C    1 
ATOM   3210 O  O    . SER   A 1 189 ? 18.62678 -2.62040  21.67788  1.000 76.93037  ? 189 SER   A O    1 
ATOM   3211 C  CB   . SER   A 1 189 ? 21.32771 -2.79480  20.00996  1.000 91.91993  ? 189 SER   A CB   1 
ATOM   3212 O  OG   . SER   A 1 189 ? 21.95179 -1.57942  20.39182  1.000 98.74544  ? 189 SER   A OG   1 
ATOM   3213 H  H    . SER   A 1 189 ? 20.51721 -1.38663  18.18156  1.000 93.31191  ? 189 SER   A H    1 
ATOM   3214 H  HA   . SER   A 1 189 ? 19.44674 -3.42687  19.45972  1.000 101.63995 ? 189 SER   A HA   1 
ATOM   3215 H  HB2  . SER   A 1 189 ? 21.36636 -3.41564  20.75424  1.000 110.31818 ? 189 SER   A HB2  1 
ATOM   3216 H  HB3  . SER   A 1 189 ? 21.79795 -3.16331  19.24577  1.000 110.31818 ? 189 SER   A HB3  1 
ATOM   3217 H  HG   . SER   A 1 189 ? 22.72901 -1.73120  20.67199  1.000 118.50880 ? 189 SER   A HG   1 
ATOM   3218 N  N    . LYS   A 1 190 ? 19.05219 -0.58131  20.81739  1.000 114.10526 ? 190 LYS   A N    1 
ATOM   3219 C  CA   . LYS   A 1 190 ? 18.39484 0.11108   21.92319  1.000 81.26270  ? 190 LYS   A CA   1 
ATOM   3220 C  C    . LYS   A 1 190 ? 16.94125 -0.32734  22.06157  1.000 99.30708  ? 190 LYS   A C    1 
ATOM   3221 O  O    . LYS   A 1 190 ? 16.47684 -0.64444  23.16497  1.000 69.66966  ? 190 LYS   A O    1 
ATOM   3222 C  CB   . LYS   A 1 190 ? 18.48789 1.62682   21.70941  1.000 125.15750 ? 190 LYS   A CB   1 
ATOM   3223 C  CG   . LYS   A 1 190 ? 17.55162 2.46389   22.57541  1.000 114.47352 ? 190 LYS   A CG   1 
ATOM   3224 C  CD   . LYS   A 1 190 ? 17.55281 3.93523   22.14264  1.000 121.39321 ? 190 LYS   A CD   1 
ATOM   3225 C  CE   . LYS   A 1 190 ? 17.04632 4.10123   20.71044  1.000 117.47021 ? 190 LYS   A CE   1 
ATOM   3226 N  NZ   . LYS   A 1 190 ? 16.75914 5.52196   20.36040  1.000 95.55802  ? 190 LYS   A NZ   1 
ATOM   3227 H  H    . LYS   A 1 190 ? 19.37276 -0.06100  20.21232  1.000 136.94058 ? 190 LYS   A H    1 
ATOM   3228 H  HA   . LYS   A 1 190 ? 18.85104 -0.10912  22.75042  1.000 97.52952  ? 190 LYS   A HA   1 
ATOM   3229 H  HB2  . LYS   A 1 190 ? 19.39480 1.90872   21.90673  1.000 150.20327 ? 190 LYS   A HB2  1 
ATOM   3230 H  HB3  . LYS   A 1 190 ? 18.27494 1.81894   20.78278  1.000 150.20327 ? 190 LYS   A HB3  1 
ATOM   3231 H  HG2  . LYS   A 1 190 ? 16.64729 2.12266   22.49385  1.000 137.38249 ? 190 LYS   A HG2  1 
ATOM   3232 H  HG3  . LYS   A 1 190 ? 17.84155 2.41761   23.49991  1.000 137.38249 ? 190 LYS   A HG3  1 
ATOM   3233 H  HD2  . LYS   A 1 190 ? 16.97298 4.44330   22.73133  1.000 145.68612 ? 190 LYS   A HD2  1 
ATOM   3234 H  HD3  . LYS   A 1 190 ? 18.45752 4.28218   22.18765  1.000 145.68612 ? 190 LYS   A HD3  1 
ATOM   3235 H  HE2  . LYS   A 1 190 ? 17.72103 3.77187   20.09628  1.000 140.97852 ? 190 LYS   A HE2  1 
ATOM   3236 H  HE3  . LYS   A 1 190 ? 16.22579 3.59486   20.60455  1.000 140.97852 ? 190 LYS   A HE3  1 
ATOM   3237 H  HZ1  . LYS   A 1 190 ? 16.50419 5.58031   19.50970  1.000 114.68389 ? 190 LYS   A HZ1  1 
ATOM   3238 H  HZ2  . LYS   A 1 190 ? 16.10860 5.83777   20.87921  1.000 114.68389 ? 190 LYS   A HZ2  1 
ATOM   3239 H  HZ3  . LYS   A 1 190 ? 17.48877 6.01788   20.47793  1.000 114.68389 ? 190 LYS   A HZ3  1 
ATOM   3240 N  N    . ASN   A 1 191 ? 16.20128 -0.33832  20.94859  1.000 112.86622 ? 191 ASN   A N    1 
ATOM   3241 C  CA   . ASN   A 1 191 ? 14.78894 -0.69883  20.99549  1.000 105.80023 ? 191 ASN   A CA   1 
ATOM   3242 C  C    . ASN   A 1 191 ? 14.57512 -2.15626  21.38903  1.000 82.16347  ? 191 ASN   A C    1 
ATOM   3243 O  O    . ASN   A 1 191 ? 13.46715 -2.52234  21.79226  1.000 64.75920  ? 191 ASN   A O    1 
ATOM   3244 C  CB   . ASN   A 1 191 ? 14.13955 -0.42357  19.63888  1.000 112.90814 ? 191 ASN   A CB   1 
ATOM   3245 C  CG   . ASN   A 1 191 ? 12.63440 -0.28329  19.73294  1.000 131.26550 ? 191 ASN   A CG   1 
ATOM   3246 O  OD1  . ASN   A 1 191 ? 11.89785 -1.26416  19.61687  1.000 108.02379 ? 191 ASN   A OD1  1 
ATOM   3247 N  ND2  . ASN   A 1 191 ? 12.16751 0.94359   19.94334  1.000 107.79891 ? 191 ASN   A ND2  1 
ATOM   3248 H  H    . ASN   A 1 191 ? 16.49305 -0.14259  20.16364  1.000 135.45373 ? 191 ASN   A H    1 
ATOM   3249 H  HA   . ASN   A 1 191 ? 14.34672 -0.14695  21.65939  1.000 126.97455 ? 191 ASN   A HA   1 
ATOM   3250 H  HB2  . ASN   A 1 191 ? 14.49674 0.40314   19.27851  1.000 135.50404 ? 191 ASN   A HB2  1 
ATOM   3251 H  HB3  . ASN   A 1 191 ? 14.33609 -1.15952  19.03834  1.000 135.50404 ? 191 ASN   A HB3  1 
ATOM   3252 H  HD21 . ASN   A 1 191 ? 11.32006 1.07655   20.00457  1.000 129.37296 ? 191 ASN   A HD21 1 
ATOM   3253 H  HD22 . ASN   A 1 191 ? 12.71294 1.60427   20.01822  1.000 129.37296 ? 191 ASN   A HD22 1 
ATOM   3254 N  N    . LEU   A 1 192 ? 15.60449 -2.99003  21.28513  1.000 71.85166  ? 192 LEU   A N    1 
ATOM   3255 C  CA   . LEU   A 1 192 ? 15.52161 -4.38598  21.68421  1.000 55.95617  ? 192 LEU   A CA   1 
ATOM   3256 C  C    . LEU   A 1 192 ? 15.91061 -4.60831  23.13792  1.000 46.48302  ? 192 LEU   A C    1 
ATOM   3257 O  O    . LEU   A 1 192 ? 15.80430 -5.74050  23.62613  1.000 46.68521  ? 192 LEU   A O    1 
ATOM   3258 C  CB   . LEU   A 1 192 ? 16.41270 -5.24264  20.77649  1.000 62.48578  ? 192 LEU   A CB   1 
ATOM   3259 C  CG   . LEU   A 1 192 ? 16.08923 -5.14124  19.28332  1.000 53.46722  ? 192 LEU   A CG   1 
ATOM   3260 C  CD1  . LEU   A 1 192 ? 16.98761 -6.04928  18.47994  1.000 37.52720  ? 192 LEU   A CD1  1 
ATOM   3261 C  CD2  . LEU   A 1 192 ? 14.62985 -5.46499  19.00559  1.000 60.26515  ? 192 LEU   A CD2  1 
ATOM   3262 H  H    . LEU   A 1 192 ? 16.37619 -2.76425  20.98002  1.000 86.23626  ? 192 LEU   A H    1 
ATOM   3263 H  HA   . LEU   A 1 192 ? 14.60610 -4.68710  21.57437  1.000 67.16167  ? 192 LEU   A HA   1 
ATOM   3264 H  HB2  . LEU   A 1 192 ? 17.33357 -4.96241  20.89636  1.000 74.99720  ? 192 LEU   A HB2  1 
ATOM   3265 H  HB3  . LEU   A 1 192 ? 16.31236 -6.17204  21.03544  1.000 74.99720  ? 192 LEU   A HB3  1 
ATOM   3266 H  HG   . LEU   A 1 192 ? 16.24608 -4.22598  19.00294  1.000 64.17493  ? 192 LEU   A HG   1 
ATOM   3267 H  HD11 . LEU   A 1 192 ? 16.77059 -5.95640  17.53911  1.000 45.04691  ? 192 LEU   A HD11 1 
ATOM   3268 H  HD12 . LEU   A 1 192 ? 17.91127 -5.79563  18.63296  1.000 45.04691  ? 192 LEU   A HD12 1 
ATOM   3269 H  HD13 . LEU   A 1 192 ? 16.84501 -6.96592  18.76338  1.000 45.04691  ? 192 LEU   A HD13 1 
ATOM   3270 H  HD21 . LEU   A 1 192 ? 14.49404 -5.51302  18.04635  1.000 72.33245  ? 192 LEU   A HD21 1 
ATOM   3271 H  HD22 . LEU   A 1 192 ? 14.41237 -6.31772  19.41357  1.000 72.33245  ? 192 LEU   A HD22 1 
ATOM   3272 H  HD23 . LEU   A 1 192 ? 14.07379 -4.76595  19.38380  1.000 72.33245  ? 192 LEU   A HD23 1 
ATOM   3273 N  N    . GLY   A 1 193 ? 16.36535 -3.57062  23.83340  1.000 42.69347  ? 193 GLY   A N    1 
ATOM   3274 C  CA   . GLY   A 1 193 ? 16.64888 -3.65803  25.24887  1.000 44.07730  ? 193 GLY   A CA   1 
ATOM   3275 C  C    . GLY   A 1 193 ? 18.06693 -4.02288  25.60683  1.000 37.28892  ? 193 GLY   A C    1 
ATOM   3276 O  O    . GLY   A 1 193 ? 18.35328 -4.24886  26.78956  1.000 40.08677  ? 193 GLY   A O    1 
ATOM   3277 H  H    . GLY   A 1 193 ? 16.51848 -2.79421  23.49676  1.000 51.24644  ? 193 GLY   A H    1 
ATOM   3278 H  HA2  . GLY   A 1 193 ? 16.45625 -2.79844  25.65494  1.000 52.90703  ? 193 GLY   A HA2  1 
ATOM   3279 H  HA3  . GLY   A 1 193 ? 16.06663 -4.32892  25.63848  1.000 52.90703  ? 193 GLY   A HA3  1 
ATOM   3280 N  N    . MET   A 1 194 ? 18.96744 -4.08574  24.63156  1.000 41.29413  ? 194 MET   A N    1 
ATOM   3281 C  CA   . MET   A 1 194 ? 20.32783 -4.50130  24.92078  1.000 37.73853  ? 194 MET   A CA   1 
ATOM   3282 C  C    . MET   A 1 194 ? 21.09274 -3.38835  25.62375  1.000 39.45310  ? 194 MET   A C    1 
ATOM   3283 O  O    . MET   A 1 194 ? 20.79196 -2.20627  25.47228  1.000 41.58983  ? 194 MET   A O    1 
ATOM   3284 C  CB   . MET   A 1 194 ? 21.05202 -4.88078  23.62089  1.000 41.04497  ? 194 MET   A CB   1 
ATOM   3285 C  CG   . MET   A 1 194 ? 20.25633 -5.78846  22.70635  1.000 45.52251  ? 194 MET   A CG   1 
ATOM   3286 S  SD   . MET   A 1 194 ? 21.14364 -6.18166  21.15917  1.000 45.35699  ? 194 MET   A SD   1 
ATOM   3287 C  CE   . MET   A 1 194 ? 22.49380 -7.12186  21.80036  1.000 37.30031  ? 194 MET   A CE   1 
ATOM   3288 H  H    . MET   A 1 194 ? 18.81534 -3.89514  23.80685  1.000 49.56723  ? 194 MET   A H    1 
ATOM   3289 H  HA   . MET   A 1 194 ? 20.30528 -5.28179  25.49630  1.000 45.30050  ? 194 MET   A HA   1 
ATOM   3290 H  HB2  . MET   A 1 194 ? 21.25074 -4.06887  23.12873  1.000 49.26824  ? 194 MET   A HB2  1 
ATOM   3291 H  HB3  . MET   A 1 194 ? 21.87517 -5.34095  23.84798  1.000 49.26824  ? 194 MET   A HB3  1 
ATOM   3292 H  HG2  . MET   A 1 194 ? 20.07399 -6.62179  23.16811  1.000 54.64128  ? 194 MET   A HG2  1 
ATOM   3293 H  HG3  . MET   A 1 194 ? 19.42348 -5.35000  22.47183  1.000 54.64128  ? 194 MET   A HG3  1 
ATOM   3294 H  HE1  . MET   A 1 194 ? 23.06524 -7.39532  21.06579  1.000 44.77464  ? 194 MET   A HE1  1 
ATOM   3295 H  HE2  . MET   A 1 194 ? 22.99500 -6.57125  22.42207  1.000 44.77464  ? 194 MET   A HE2  1 
ATOM   3296 H  HE3  . MET   A 1 194 ? 22.14557 -7.90347  22.25723  1.000 44.77464  ? 194 MET   A HE3  1 
ATOM   3297 N  N    . THR   A 1 195 ? 22.09445 -3.78628  26.39887  1.000 42.44713  ? 195 THR   A N    1 
ATOM   3298 C  CA   . THR   A 1 195 ? 23.02153 -2.85331  27.02829  1.000 42.52042  ? 195 THR   A CA   1 
ATOM   3299 C  C    . THR   A 1 195 ? 24.18728 -2.58880  26.08150  1.000 55.32092  ? 195 THR   A C    1 
ATOM   3300 O  O    . THR   A 1 195 ? 24.81375 -3.52844  25.58752  1.000 42.39410  ? 195 THR   A O    1 
ATOM   3301 C  CB   . THR   A 1 195 ? 23.53321 -3.41847  28.35230  1.000 41.35078  ? 195 THR   A CB   1 
ATOM   3302 O  OG1  . THR   A 1 195 ? 22.42390 -3.59845  29.24929  1.000 44.62146  ? 195 THR   A OG1  1 
ATOM   3303 C  CG2  . THR   A 1 195 ? 24.55441 -2.48512  28.98000  1.000 45.54710  ? 195 THR   A CG2  1 
ATOM   3304 H  H    . THR   A 1 195 ? 22.26222 -4.61011  26.57986  1.000 50.95083  ? 195 THR   A H    1 
ATOM   3305 H  HA   . THR   A 1 195 ? 22.57132 -2.01388  27.21150  1.000 51.03877  ? 195 THR   A HA   1 
ATOM   3306 H  HB   . THR   A 1 195 ? 23.96785 -4.27164  28.19714  1.000 49.63521  ? 195 THR   A HB   1 
ATOM   3307 H  HG1  . THR   A 1 195 ? 22.68928 -3.93954  29.96959  1.000 53.56002  ? 195 THR   A HG1  1 
ATOM   3308 H  HG21 . THR   A 1 195 ? 24.72307 -2.74738  29.89852  1.000 54.67079  ? 195 THR   A HG21 1 
ATOM   3309 H  HG22 . THR   A 1 195 ? 25.38714 -2.52262  28.48395  1.000 54.67079  ? 195 THR   A HG22 1 
ATOM   3310 H  HG23 . THR   A 1 195 ? 24.22205 -1.57391  28.96877  1.000 54.67079  ? 195 THR   A HG23 1 
ATOM   3311 N  N    . SER   A 1 196 ? 24.47855 -1.31345  25.83090  1.000 43.74029  ? 196 SER   A N    1 
ATOM   3312 C  CA   . SER   A 1 196 ? 25.47508 -0.92708  24.84086  1.000 33.41540  ? 196 SER   A CA   1 
ATOM   3313 C  C    . SER   A 1 196 ? 26.77703 -0.54426  25.52647  1.000 48.38897  ? 196 SER   A C    1 
ATOM   3314 O  O    . SER   A 1 196 ? 26.77550 0.19886   26.51465  1.000 42.60150  ? 196 SER   A O    1 
ATOM   3315 C  CB   . SER   A 1 196 ? 24.95843 0.22547   23.97542  1.000 46.95439  ? 196 SER   A CB   1 
ATOM   3316 O  OG   . SER   A 1 196 ? 24.70598 1.37134   24.75548  1.000 61.51451  ? 196 SER   A OG   1 
ATOM   3317 H  H    . SER   A 1 196 ? 24.10613 -0.64766  26.22792  1.000 52.50262  ? 196 SER   A H    1 
ATOM   3318 H  HA   . SER   A 1 196 ? 25.66200 -1.68261  24.26195  1.000 40.11276  ? 196 SER   A HA   1 
ATOM   3319 H  HB2  . SER   A 1 196 ? 25.62697 0.44106   23.30648  1.000 56.35955  ? 196 SER   A HB2  1 
ATOM   3320 H  HB3  . SER   A 1 196 ? 24.13426 -0.04961  23.54416  1.000 56.35955  ? 196 SER   A HB3  1 
ATOM   3321 H  HG   . SER   A 1 196 ? 24.37355 1.97680   24.27745  1.000 73.83168  ? 196 SER   A HG   1 
ATOM   3322 N  N    . ILE   A 1 197 ? 27.88153 -1.07974  25.01759  1.000 39.48332  ? 197 ILE   A N    1 
ATOM   3323 C  CA   . ILE   A 1 197 ? 29.22497 -0.68946  25.42666  1.000 36.76723  ? 197 ILE   A CA   1 
ATOM   3324 C  C    . ILE   A 1 197 ? 29.90774 -0.08532  24.20500  1.000 48.08536  ? 197 ILE   A C    1 
ATOM   3325 O  O    . ILE   A 1 197 ? 30.02955 -0.74479  23.16048  1.000 38.98515  ? 197 ILE   A O    1 
ATOM   3326 C  CB   . ILE   A 1 197 ? 30.03445 -1.87102  25.97199  1.000 36.97104  ? 197 ILE   A CB   1 
ATOM   3327 C  CG1  . ILE   A 1 197 ? 29.31412 -2.52327  27.14507  1.000 36.14481  ? 197 ILE   A CG1  1 
ATOM   3328 C  CG2  . ILE   A 1 197 ? 31.44739 -1.42886  26.36752  1.000 36.65542  ? 197 ILE   A CG2  1 
ATOM   3329 C  CD1  . ILE   A 1 197 ? 30.12883 -3.61728  27.81616  1.000 40.81053  ? 197 ILE   A CD1  1 
ATOM   3330 H  H    . ILE   A 1 197 ? 27.87712 -1.69178  24.41345  1.000 47.39425  ? 197 ILE   A H    1 
ATOM   3331 H  HA   . ILE   A 1 197 ? 29.16819 -0.01943  26.12575  1.000 44.13494  ? 197 ILE   A HA   1 
ATOM   3332 H  HB   . ILE   A 1 197 ? 30.11480 -2.53124  25.26590  1.000 44.37952  ? 197 ILE   A HB   1 
ATOM   3333 H  HG12 . ILE   A 1 197 ? 29.12024 -1.84491  27.81075  1.000 43.38805  ? 197 ILE   A HG12 1 
ATOM   3334 H  HG13 . ILE   A 1 197 ? 28.48864 -2.91977  26.82528  1.000 43.38805  ? 197 ILE   A HG13 1 
ATOM   3335 H  HG21 . ILE   A 1 197 ? 31.98192 -2.21499  26.56035  1.000 44.00077  ? 197 ILE   A HG21 1 
ATOM   3336 H  HG22 . ILE   A 1 197 ? 31.84079 -0.93361  25.63209  1.000 44.00077  ? 197 ILE   A HG22 1 
ATOM   3337 H  HG23 . ILE   A 1 197 ? 31.39299 -0.86464  27.15466  1.000 44.00077  ? 197 ILE   A HG23 1 
ATOM   3338 H  HD11 . ILE   A 1 197 ? 29.55998 -4.09896  28.43688  1.000 48.98691  ? 197 ILE   A HD11 1 
ATOM   3339 H  HD12 . ILE   A 1 197 ? 30.46442 -4.22290  27.13683  1.000 48.98691  ? 197 ILE   A HD12 1 
ATOM   3340 H  HD13 . ILE   A 1 197 ? 30.86982 -3.21177  28.29301  1.000 48.98691  ? 197 ILE   A HD13 1 
ATOM   3341 N  N    . LEU   A 1 198 ? 30.33522 1.17166   24.32322  1.000 38.50654  ? 198 LEU   A N    1 
ATOM   3342 C  CA   . LEU   A 1 198 ? 31.11102 1.81610   23.27493  1.000 43.62031  ? 198 LEU   A CA   1 
ATOM   3343 C  C    . LEU   A 1 198 ? 32.59753 1.59865   23.53139  1.000 35.52740  ? 198 LEU   A C    1 
ATOM   3344 O  O    . LEU   A 1 198 ? 33.09070 1.85864   24.63411  1.000 40.86653  ? 198 LEU   A O    1 
ATOM   3345 C  CB   . LEU   A 1 198 ? 30.79345 3.30798   23.20211  1.000 53.60952  ? 198 LEU   A CB   1 
ATOM   3346 C  CG   . LEU   A 1 198 ? 31.63856 4.11494   22.21095  1.000 42.80010  ? 198 LEU   A CG   1 
ATOM   3347 C  CD1  . LEU   A 1 198 ? 31.32475 3.73527   20.77527  1.000 48.06555  ? 198 LEU   A CD1  1 
ATOM   3348 C  CD2  . LEU   A 1 198 ? 31.43568 5.61336   22.43326  1.000 55.11071  ? 198 LEU   A CD2  1 
ATOM   3349 H  H    . LEU   A 1 198 ? 30.18573 1.67165   25.00679  1.000 46.22212  ? 198 LEU   A H    1 
ATOM   3350 H  HA   . LEU   A 1 198 ? 30.88643 1.42159   22.41771  1.000 52.35864  ? 198 LEU   A HA   1 
ATOM   3351 H  HB2  . LEU   A 1 198 ? 29.86502 3.40905   22.94000  1.000 64.34569  ? 198 LEU   A HB2  1 
ATOM   3352 H  HB3  . LEU   A 1 198 ? 30.93359 3.69223   24.08166  1.000 64.34569  ? 198 LEU   A HB3  1 
ATOM   3353 H  HG   . LEU   A 1 198 ? 32.57379 3.90815   22.36423  1.000 51.37439  ? 198 LEU   A HG   1 
ATOM   3354 H  HD11 . LEU   A 1 198 ? 31.92536 4.21464   20.18334  1.000 57.69294  ? 198 LEU   A HD11 1 
ATOM   3355 H  HD12 . LEU   A 1 198 ? 31.44742 2.77911   20.66744  1.000 57.69294  ? 198 LEU   A HD12 1 
ATOM   3356 H  HD13 . LEU   A 1 198 ? 30.40561 3.97506   20.57889  1.000 57.69294  ? 198 LEU   A HD13 1 
ATOM   3357 H  HD21 . LEU   A 1 198 ? 32.00199 6.10359   21.81693  1.000 66.14712  ? 198 LEU   A HD21 1 
ATOM   3358 H  HD22 . LEU   A 1 198 ? 30.50458 5.83315   22.27313  1.000 66.14712  ? 198 LEU   A HD22 1 
ATOM   3359 H  HD23 . LEU   A 1 198 ? 31.67469 5.83218   23.34753  1.000 66.14712  ? 198 LEU   A HD23 1 
ATOM   3360 N  N    . LEU   A 1 199 ? 33.30381 1.11130   22.51060  1.000 38.23090  ? 199 LEU   A N    1 
ATOM   3361 C  CA   . LEU   A 1 199 ? 34.75697 0.99775   22.54971  1.000 39.52368  ? 199 LEU   A CA   1 
ATOM   3362 C  C    . LEU   A 1 199 ? 35.33178 2.26306   21.91481  1.000 34.23658  ? 199 LEU   A C    1 
ATOM   3363 O  O    . LEU   A 1 199 ? 35.18167 2.48354   20.70443  1.000 40.64937  ? 199 LEU   A O    1 
ATOM   3364 C  CB   . LEU   A 1 199 ? 35.23062 -0.24922  21.80550  1.000 55.78350  ? 199 LEU   A CB   1 
ATOM   3365 C  CG   . LEU   A 1 199 ? 36.74559 -0.41813  21.67792  1.000 53.33948  ? 199 LEU   A CG   1 
ATOM   3366 C  CD1  . LEU   A 1 199 ? 37.38263 -0.62774  23.03898  1.000 41.06057  ? 199 LEU   A CD1  1 
ATOM   3367 C  CD2  . LEU   A 1 199 ? 37.09890 -1.56678  20.74172  1.000 69.76035  ? 199 LEU   A CD2  1 
ATOM   3368 H  H    . LEU   A 1 199 ? 32.95591 0.83616   21.77381  1.000 45.89135  ? 199 LEU   A H    1 
ATOM   3369 H  HA   . LEU   A 1 199 ? 35.05819 0.92731   23.46906  1.000 47.44269  ? 199 LEU   A HA   1 
ATOM   3370 H  HB2  . LEU   A 1 199 ? 34.89319 -1.02811  22.27494  1.000 66.95448  ? 199 LEU   A HB2  1 
ATOM   3371 H  HB3  . LEU   A 1 199 ? 34.86793 -0.22089  20.90631  1.000 66.95448  ? 199 LEU   A HB3  1 
ATOM   3372 H  HG   . LEU   A 1 199 ? 37.10917 0.39581   21.29555  1.000 64.02165  ? 199 LEU   A HG   1 
ATOM   3373 H  HD11 . LEU   A 1 199 ? 38.34137 -0.72413  22.92745  1.000 49.28696  ? 199 LEU   A HD11 1 
ATOM   3374 H  HD12 . LEU   A 1 199 ? 37.19038 0.14036   23.59931  1.000 49.28696  ? 199 LEU   A HD12 1 
ATOM   3375 H  HD13 . LEU   A 1 199 ? 37.01392 -1.43031  23.44001  1.000 49.28696  ? 199 LEU   A HD13 1 
ATOM   3376 H  HD21 . LEU   A 1 199 ? 38.06428 -1.64171  20.68411  1.000 83.72669  ? 199 LEU   A HD21 1 
ATOM   3377 H  HD22 . LEU   A 1 199 ? 36.72381 -2.38871  21.09474  1.000 83.72669  ? 199 LEU   A HD22 1 
ATOM   3378 H  HD23 . LEU   A 1 199 ? 36.72833 -1.38426  19.86407  1.000 83.72669  ? 199 LEU   A HD23 1 
ATOM   3379 N  N    . ASP   A 1 200 ? 35.98168 3.08661   22.72976  1.000 44.16850  ? 200 ASP   A N    1 
ATOM   3380 C  CA   . ASP   A 1 200 ? 36.60750 4.34219   22.30531  1.000 43.02012  ? 200 ASP   A CA   1 
ATOM   3381 C  C    . ASP   A 1 200 ? 38.04569 4.29392   22.81155  1.000 40.45914  ? 200 ASP   A C    1 
ATOM   3382 O  O    . ASP   A 1 200 ? 38.36764 4.83594   23.86726  1.000 44.85062  ? 200 ASP   A O    1 
ATOM   3383 C  CB   . ASP   A 1 200 ? 35.83580 5.53734   22.85000  1.000 61.48230  ? 200 ASP   A CB   1 
ATOM   3384 C  CG   . ASP   A 1 200 ? 36.29572 6.85621   22.25083  1.000 66.80843  ? 200 ASP   A CG   1 
ATOM   3385 O  OD1  . ASP   A 1 200 ? 37.26129 6.85357   21.46318  1.000 46.13073  ? 200 ASP   A OD1  1 
ATOM   3386 O  OD2  . ASP   A 1 200 ? 35.67786 7.89294   22.57119  1.000 44.66592  ? 200 ASP   A OD2  1 
ATOM   3387 H  H    . ASP   A 1 200 ? 36.07948 2.93577   23.57076  1.000 53.01647  ? 200 ASP   A H    1 
ATOM   3388 H  HA   . ASP   A 1 200 ? 36.61607 4.41097   21.33779  1.000 51.63841  ? 200 ASP   A HA   1 
ATOM   3389 H  HB2  . ASP   A 1 200 ? 34.89443 5.42634   22.64407  1.000 73.79303  ? 200 ASP   A HB2  1 
ATOM   3390 H  HB3  . ASP   A 1 200 ? 35.96201 5.58401   23.81062  1.000 73.79303  ? 200 ASP   A HB3  1 
ATOM   3391 N  N    . ARG   A 1 201 ? 38.91737 3.62913   22.04834  1.000 44.26798  ? 201 ARG   A N    1 
ATOM   3392 C  CA   . ARG   A 1 201 ? 40.26374 3.35610   22.54248  1.000 46.38265  ? 201 ARG   A CA   1 
ATOM   3393 C  C    . ARG   A 1 201 ? 41.08038 4.62871   22.73295  1.000 43.74718  ? 201 ARG   A C    1 
ATOM   3394 O  O    . ARG   A 1 201 ? 41.92715 4.68875   23.63541  1.000 49.96425  ? 201 ARG   A O    1 
ATOM   3395 C  CB   . ARG   A 1 201 ? 40.99128 2.41358   21.58446  1.000 50.55055  ? 201 ARG   A CB   1 
ATOM   3396 C  CG   . ARG   A 1 201 ? 40.31976 1.06621   21.42668  1.000 47.64946  ? 201 ARG   A CG   1 
ATOM   3397 C  CD   . ARG   A 1 201 ? 41.15186 0.12810   20.56879  1.000 66.62365  ? 201 ARG   A CD   1 
ATOM   3398 N  NE   . ARG   A 1 201 ? 42.25581 -0.47761  21.30633  1.000 71.81854  ? 201 ARG   A NE   1 
ATOM   3399 C  CZ   . ARG   A 1 201 ? 42.16863 -1.62571  21.96849  1.000 51.63729  ? 201 ARG   A CZ   1 
ATOM   3400 N  NH1  . ARG   A 1 201 ? 41.03490 -2.30570  22.02585  1.000 53.15965  ? 201 ARG   A NH1  1 
ATOM   3401 N  NH2  . ARG   A 1 201 ? 43.25029 -2.11195  22.56925  1.000 66.58880  ? 201 ARG   A NH2  1 
ATOM   3402 H  H    . ARG   A 1 201 ? 38.75593 3.33226   21.25752  1.000 53.13585  ? 201 ARG   A H    1 
ATOM   3403 H  HA   . ARG   A 1 201 ? 40.18521 2.92161   23.40617  1.000 55.67345  ? 201 ARG   A HA   1 
ATOM   3404 H  HB2  . ARG   A 1 201 ? 41.03104 2.82892   20.70878  1.000 60.67493  ? 201 ARG   A HB2  1 
ATOM   3405 H  HB3  . ARG   A 1 201 ? 41.88840 2.25982   21.91976  1.000 60.67493  ? 201 ARG   A HB3  1 
ATOM   3406 H  HG2  . ARG   A 1 201 ? 40.20498 0.65992   22.29999  1.000 57.19363  ? 201 ARG   A HG2  1 
ATOM   3407 H  HG3  . ARG   A 1 201 ? 39.45677 1.18505   21.00005  1.000 57.19363  ? 201 ARG   A HG3  1 
ATOM   3408 H  HD2  . ARG   A 1 201 ? 40.58437 -0.58568  20.23808  1.000 79.96265  ? 201 ARG   A HD2  1 
ATOM   3409 H  HD3  . ARG   A 1 201 ? 41.52534 0.62655   19.82518  1.000 79.96265  ? 201 ARG   A HD3  1 
ATOM   3410 H  HE   . ARG   A 1 201 ? 43.01044 -0.06518  21.31264  1.000 86.19652  ? 201 ARG   A HE   1 
ATOM   3411 H  HH11 . ARG   A 1 201 ? 40.33326 -2.00612  21.62893  1.000 63.80586  ? 201 ARG   A HH11 1 
ATOM   3412 H  HH12 . ARG   A 1 201 ? 40.99972 -3.04720  22.46004  1.000 63.80586  ? 201 ARG   A HH12 1 
ATOM   3413 H  HH21 . ARG   A 1 201 ? 43.99500 -1.68396  22.52636  1.000 79.92083  ? 201 ARG   A HH21 1 
ATOM   3414 H  HH22 . ARG   A 1 201 ? 43.20531 -2.85449  23.00077  1.000 79.92083  ? 201 ARG   A HH22 1 
ATOM   3415 N  N    . LYS   A 1 202 ? 40.84370 5.64795   21.90929  1.000 46.54259  ? 202 LYS   A N    1 
ATOM   3416 C  CA   . LYS   A 1 202 ? 41.60479 6.89071   21.97878  1.000 62.30522  ? 202 LYS   A CA   1 
ATOM   3417 C  C    . LYS   A 1 202 ? 40.80573 8.04463   22.57426  1.000 65.86543  ? 202 LYS   A C    1 
ATOM   3418 O  O    . LYS   A 1 202 ? 41.28344 9.18389   22.57880  1.000 56.60126  ? 202 LYS   A O    1 
ATOM   3419 C  CB   . LYS   A 1 202 ? 42.11056 7.27479   20.58245  1.000 56.08954  ? 202 LYS   A CB   1 
ATOM   3420 C  CG   . LYS   A 1 202 ? 43.15035 6.31634   20.00794  1.000 66.57896  ? 202 LYS   A CG   1 
ATOM   3421 C  CD   . LYS   A 1 202 ? 44.05371 7.01964   18.99589  1.000 73.24241  ? 202 LYS   A CD   1 
ATOM   3422 C  CE   . LYS   A 1 202 ? 45.21428 6.13309   18.56631  1.000 90.98541  ? 202 LYS   A CE   1 
ATOM   3423 N  NZ   . LYS   A 1 202 ? 44.78923 5.05950   17.62317  1.000 101.44622 ? 202 LYS   A NZ   1 
ATOM   3424 H  H    . LYS   A 1 202 ? 40.24087 5.64211   21.29597  1.000 55.86537  ? 202 LYS   A H    1 
ATOM   3425 H  HA   . LYS   A 1 202 ? 42.37325 6.74259   22.55187  1.000 74.78053  ? 202 LYS   A HA   1 
ATOM   3426 H  HB2  . LYS   A 1 202 ? 41.35619 7.29035   19.97287  1.000 67.32172  ? 202 LYS   A HB2  1 
ATOM   3427 H  HB3  . LYS   A 1 202 ? 42.51626 8.15454   20.63076  1.000 67.32172  ? 202 LYS   A HB3  1 
ATOM   3428 H  HG2  . LYS   A 1 202 ? 43.70473 5.97403   20.72655  1.000 79.90903  ? 202 LYS   A HG2  1 
ATOM   3429 H  HG3  . LYS   A 1 202 ? 42.70000 5.58403   19.55871  1.000 79.90903  ? 202 LYS   A HG3  1 
ATOM   3430 H  HD2  . LYS   A 1 202 ? 43.53618 7.24629   18.20741  1.000 87.90516  ? 202 LYS   A HD2  1 
ATOM   3431 H  HD3  . LYS   A 1 202 ? 44.41796 7.82454   19.39632  1.000 87.90516  ? 202 LYS   A HD3  1 
ATOM   3432 H  HE2  . LYS   A 1 202 ? 45.88256 6.67767   18.12165  1.000 109.19676 ? 202 LYS   A HE2  1 
ATOM   3433 H  HE3  . LYS   A 1 202 ? 45.59866 5.71066   19.35035  1.000 109.19676 ? 202 LYS   A HE3  1 
ATOM   3434 H  HZ1  . LYS   A 1 202 ? 45.48840 4.55609   17.39992  1.000 121.74974 ? 202 LYS   A HZ1  1 
ATOM   3435 H  HZ2  . LYS   A 1 202 ? 44.17290 4.54426   18.00625  1.000 121.74974 ? 202 LYS   A HZ2  1 
ATOM   3436 H  HZ3  . LYS   A 1 202 ? 44.44605 5.42058   16.88564  1.000 121.74974 ? 202 LYS   A HZ3  1 
ATOM   3437 N  N    . GLY   A 1 203 ? 39.60904 7.78245   23.08324  1.000 49.34736  ? 203 GLY   A N    1 
ATOM   3438 C  CA   . GLY   A 1 203 ? 38.78341 8.86343   23.59336  1.000 58.53954  ? 203 GLY   A CA   1 
ATOM   3439 C  C    . GLY   A 1 203 ? 38.47065 9.91549   22.55286  1.000 51.59863  ? 203 GLY   A C    1 
ATOM   3440 O  O    . GLY   A 1 203 ? 38.49430 11.11587  22.85685  1.000 71.97584  ? 203 GLY   A O    1 
ATOM   3441 H  H    . GLY   A 1 203 ? 39.25836 6.99951   23.14343  1.000 59.23111  ? 203 GLY   A H    1 
ATOM   3442 H  HA2  . GLY   A 1 203 ? 37.94477 8.49768   23.91555  1.000 70.26172  ? 203 GLY   A HA2  1 
ATOM   3443 H  HA3  . GLY   A 1 203 ? 39.24397 9.29420   24.33040  1.000 70.26172  ? 203 GLY   A HA3  1 
ATOM   3444 N  N    . GLU   A 1 204 ? 38.16850 9.49087   21.33046  1.000 47.51975  ? 204 GLU   A N    1 
ATOM   3445 C  CA   . GLU   A 1 204 ? 37.95156 10.39633  20.21283  1.000 61.85345  ? 204 GLU   A CA   1 
ATOM   3446 C  C    . GLU   A 1 204 ? 36.47915 10.58570  19.86514  1.000 54.47495  ? 204 GLU   A C    1 
ATOM   3447 O  O    . GLU   A 1 204 ? 36.17550 11.24946  18.87066  1.000 47.66119  ? 204 GLU   A O    1 
ATOM   3448 C  CB   . GLU   A 1 204 ? 38.68968 9.88303   18.96674  1.000 56.22986  ? 204 GLU   A CB   1 
ATOM   3449 C  CG   . GLU   A 1 204 ? 40.20517 9.82835   19.09031  1.000 71.31667  ? 204 GLU   A CG   1 
ATOM   3450 C  CD   . GLU   A 1 204 ? 40.86242 9.10988   17.91585  1.000 69.79274  ? 204 GLU   A CD   1 
ATOM   3451 O  OE1  . GLU   A 1 204 ? 40.21039 8.23416   17.29788  1.000 73.16584  ? 204 GLU   A OE1  1 
ATOM   3452 O  OE2  . GLU   A 1 204 ? 42.03270 9.41983   17.61315  1.000 84.23562  ? 204 GLU   A OE2  1 
ATOM   3453 H  H    . GLU   A 1 204 ? 38.08186 8.66147   21.12023  1.000 57.03797  ? 204 GLU   A H    1 
ATOM   3454 H  HA   . GLU   A 1 204 ? 38.31618 11.26173  20.45582  1.000 74.23841  ? 204 GLU   A HA   1 
ATOM   3455 H  HB2  . GLU   A 1 204 ? 38.38127 8.98319   18.77682  1.000 67.49011  ? 204 GLU   A HB2  1 
ATOM   3456 H  HB3  . GLU   A 1 204 ? 38.48004 10.46947  18.22308  1.000 67.49011  ? 204 GLU   A HB3  1 
ATOM   3457 H  HG2  . GLU   A 1 204 ? 40.55334 10.73314  19.12240  1.000 85.59427  ? 204 GLU   A HG2  1 
ATOM   3458 H  HG3  . GLU   A 1 204 ? 40.43993 9.35352   19.90291  1.000 85.59427  ? 204 GLU   A HG3  1 
ATOM   3459 N  N    . LYS   A 1 205 ? 35.55838 10.01515  20.64832  1.000 46.90795  ? 205 LYS   A N    1 
ATOM   3460 C  CA   . LYS   A 1 205 ? 34.14661 10.02228  20.29286  1.000 43.17282  ? 205 LYS   A CA   1 
ATOM   3461 C  C    . LYS   A 1 205 ? 33.28642 10.53806  21.43738  1.000 45.49609  ? 205 LYS   A C    1 
ATOM   3462 O  O    . LYS   A 1 205 ? 32.11393 10.16631  21.54955  1.000 40.96077  ? 205 LYS   A O    1 
ATOM   3463 C  CB   . LYS   A 1 205 ? 33.69268 8.62128   19.87469  1.000 59.47960  ? 205 LYS   A CB   1 
ATOM   3464 C  CG   . LYS   A 1 205 ? 34.24550 8.17910   18.52516  1.000 57.65081  ? 205 LYS   A CG   1 
ATOM   3465 C  CD   . LYS   A 1 205 ? 33.90531 6.73612   18.20054  1.000 69.67293  ? 205 LYS   A CD   1 
ATOM   3466 C  CE   . LYS   A 1 205 ? 34.85790 5.76805   18.88597  1.000 64.01782  ? 205 LYS   A CE   1 
ATOM   3467 N  NZ   . LYS   A 1 205 ? 35.06470 4.53616   18.06329  1.000 75.88057  ? 205 LYS   A NZ   1 
ATOM   3468 H  H    . LYS   A 1 205 ? 35.73277 9.61826   21.39106  1.000 56.30381  ? 205 LYS   A H    1 
ATOM   3469 H  HA   . LYS   A 1 205 ? 34.02076 10.62291  19.54166  1.000 51.82166  ? 205 LYS   A HA   1 
ATOM   3470 H  HB2  . LYS   A 1 205 ? 33.99213 7.98370   20.54157  1.000 71.38980  ? 205 LYS   A HB2  1 
ATOM   3471 H  HB3  . LYS   A 1 205 ? 32.72447 8.61075   19.81683  1.000 71.38980  ? 205 LYS   A HB3  1 
ATOM   3472 H  HG2  . LYS   A 1 205 ? 33.86932 8.74020   17.82905  1.000 69.19525  ? 205 LYS   A HG2  1 
ATOM   3473 H  HG3  . LYS   A 1 205 ? 35.21164 8.26502   18.53461  1.000 69.19525  ? 205 LYS   A HG3  1 
ATOM   3474 H  HD2  . LYS   A 1 205 ? 33.00447 6.54278   18.50386  1.000 83.62179  ? 205 LYS   A HD2  1 
ATOM   3475 H  HD3  . LYS   A 1 205 ? 33.96935 6.59908   17.24241  1.000 83.62179  ? 205 LYS   A HD3  1 
ATOM   3476 H  HE2  . LYS   A 1 205 ? 35.71769 6.19856   19.01374  1.000 76.83565  ? 205 LYS   A HE2  1 
ATOM   3477 H  HE3  . LYS   A 1 205 ? 34.48795 5.50497   19.74319  1.000 76.83565  ? 205 LYS   A HE3  1 
ATOM   3478 H  HZ1  . LYS   A 1 205 ? 35.62002 3.98048   18.48155  1.000 91.07096  ? 205 LYS   A HZ1  1 
ATOM   3479 H  HZ2  . LYS   A 1 205 ? 34.28715 4.12334   17.93258  1.000 91.07096  ? 205 LYS   A HZ2  1 
ATOM   3480 H  HZ3  . LYS   A 1 205 ? 35.41320 4.75254   17.27346  1.000 91.07096  ? 205 LYS   A HZ3  1 
ATOM   3481 N  N    . ARG   A 1 206 ? 33.84522 11.42570  22.26673  1.000 47.48262  ? 206 ARG   A N    1 
ATOM   3482 C  CA   A ARG   A 1 206 ? 33.13715 11.89341  23.45567  0.700 38.34334  ? 206 ARG   A CA   1 
ATOM   3483 C  CA   B ARG   A 1 206 ? 33.12912 11.86772  23.45984  0.300 39.05017  ? 206 ARG   A CA   1 
ATOM   3484 C  C    . ARG   A 1 206 ? 31.74894 12.41338  23.12663  1.000 40.22464  ? 206 ARG   A C    1 
ATOM   3485 O  O    . ARG   A 1 206 ? 30.82816 12.30050  23.94561  1.000 49.42549  ? 206 ARG   A O    1 
ATOM   3486 C  CB   A ARG   A 1 206 ? 33.93495 13.00080  24.15159  0.700 43.71390  ? 206 ARG   A CB   1 
ATOM   3487 C  CB   B ARG   A 1 206 ? 33.96185 12.91499  24.20719  0.300 43.69590  ? 206 ARG   A CB   1 
ATOM   3488 C  CG   A ARG   A 1 206 ? 35.27326 12.56948  24.71606  0.700 51.66207  ? 206 ARG   A CG   1 
ATOM   3489 C  CG   B ARG   A 1 206 ? 35.05374 12.30462  25.08379  0.300 40.65564  ? 206 ARG   A CG   1 
ATOM   3490 C  CD   A ARG   A 1 206 ? 35.92562 13.70768  25.50267  0.700 66.57797  ? 206 ARG   A CD   1 
ATOM   3491 C  CD   B ARG   A 1 206 ? 36.13718 13.31379  25.45341  0.300 62.08523  ? 206 ARG   A CD   1 
ATOM   3492 N  NE   A ARG   A 1 206 ? 35.23043 13.96669  26.75939  0.700 64.45552  ? 206 ARG   A NE   1 
ATOM   3493 N  NE   B ARG   A 1 206 ? 37.47493 12.80333  25.16608  0.300 48.14602  ? 206 ARG   A NE   1 
ATOM   3494 C  CZ   A ARG   A 1 206 ? 35.59638 13.46882  27.93343  0.700 62.22509  ? 206 ARG   A CZ   1 
ATOM   3495 C  CZ   B ARG   A 1 206 ? 38.22762 12.12758  26.02439  0.300 41.01753  ? 206 ARG   A CZ   1 
ATOM   3496 N  NH1  A ARG   A 1 206 ? 36.66330 12.69469  28.05549  0.700 60.20528  ? 206 ARG   A NH1  1 
ATOM   3497 N  NH1  B ARG   A 1 206 ? 37.81550 11.87168  27.25468  0.300 40.51784  ? 206 ARG   A NH1  1 
ATOM   3498 N  NH2  A ARG   A 1 206 ? 34.87459 13.75540  29.01168  0.700 63.76817  ? 206 ARG   A NH2  1 
ATOM   3499 N  NH2  B ARG   A 1 206 ? 39.42606 11.70294  25.63949  0.300 43.48514  ? 206 ARG   A NH2  1 
ATOM   3500 H  H    A ARG   A 1 206 ? 34.62699 11.76864  22.16270  0.700 56.99342  ? 206 ARG   A H    1 
ATOM   3501 H  H    B ARG   A 1 206 ? 34.62229 11.77875  22.16131  0.300 56.99342  ? 206 ARG   A H    1 
ATOM   3502 H  HA   A ARG   A 1 206 ? 33.05028 11.14292  24.06405  0.700 46.02628  ? 206 ARG   A HA   1 
ATOM   3503 H  HA   B ARG   A 1 206 ? 33.00422 11.10872  24.05079  0.300 46.87448  ? 206 ARG   A HA   1 
ATOM   3504 H  HB2  A ARG   A 1 206 ? 34.10473 13.70696  23.50861  0.700 52.47095  ? 206 ARG   A HB2  1 
ATOM   3505 H  HB2  B ARG   A 1 206 ? 34.38986 13.49612  23.55912  0.300 52.44935  ? 206 ARG   A HB2  1 
ATOM   3506 H  HB3  A ARG   A 1 206 ? 33.40552 13.34346  24.88860  0.700 52.47095  ? 206 ARG   A HB3  1 
ATOM   3507 H  HB3  B ARG   A 1 206 ? 33.37432 13.43252  24.77979  0.300 52.44935  ? 206 ARG   A HB3  1 
ATOM   3508 H  HG2  A ARG   A 1 206 ? 35.14482 11.81663  25.31407  0.700 62.00876  ? 206 ARG   A HG2  1 
ATOM   3509 H  HG2  B ARG   A 1 206 ? 34.65532 11.97676  25.90517  0.300 48.80104  ? 206 ARG   A HG2  1 
ATOM   3510 H  HG3  A ARG   A 1 206 ? 35.86531 12.31896  23.98969  0.700 62.00876  ? 206 ARG   A HG3  1 
ATOM   3511 H  HG3  B ARG   A 1 206 ? 35.47441 11.57382  24.60435  0.300 48.80104  ? 206 ARG   A HG3  1 
ATOM   3512 H  HD2  A ARG   A 1 206 ? 36.84370 13.47028  25.70679  0.700 79.90784  ? 206 ARG   A HD2  1 
ATOM   3513 H  HD2  B ARG   A 1 206 ? 36.00561 14.12661  24.94066  0.300 74.51655  ? 206 ARG   A HD2  1 
ATOM   3514 H  HD3  A ARG   A 1 206 ? 35.90304 14.51831  24.97044  0.700 79.90784  ? 206 ARG   A HD3  1 
ATOM   3515 H  HD3  B ARG   A 1 206 ? 36.08340 13.50776  26.40230  0.300 74.51655  ? 206 ARG   A HD3  1 
ATOM   3516 H  HE   A ARG   A 1 206 ? 34.53764 14.47577  26.73750  0.700 77.36090  ? 206 ARG   A HE   1 
ATOM   3517 H  HE   B ARG   A 1 206 ? 37.79844 12.95164  24.38317  0.300 57.78950  ? 206 ARG   A HE   1 
ATOM   3518 H  HH11 A ARG   A 1 206 ? 37.13742 12.50375  27.36386  0.700 72.26061  ? 206 ARG   A HH11 1 
ATOM   3519 H  HH11 B ARG   A 1 206 ? 37.04282 12.14521  27.51496  0.300 48.63568  ? 206 ARG   A HH11 1 
ATOM   3520 H  HH12 A ARG   A 1 206 ? 36.88229 12.38274  28.82641  0.700 72.26061  ? 206 ARG   A HH12 1 
ATOM   3521 H  HH12 B ARG   A 1 206 ? 38.32019 11.43175  27.79445  0.300 48.63568  ? 206 ARG   A HH12 1 
ATOM   3522 H  HH21 A ARG   A 1 206 ? 34.18000 14.25783  28.94310  0.700 76.53607  ? 206 ARG   A HH21 1 
ATOM   3523 H  HH21 B ARG   A 1 206 ? 39.70496 11.86708  24.84270  0.300 52.19644  ? 206 ARG   A HH21 1 
ATOM   3524 H  HH22 A ARG   A 1 206 ? 35.10204 13.43844  29.77810  0.700 76.53607  ? 206 ARG   A HH22 1 
ATOM   3525 H  HH22 B ARG   A 1 206 ? 39.92301 11.26388  26.18710  0.300 52.19644  ? 206 ARG   A HH22 1 
ATOM   3526 N  N    . GLU   A 1 207 ? 31.57412 12.99174  21.93587  1.000 37.14772  ? 207 GLU   A N    1 
ATOM   3527 C  CA   . GLU   A 1 207 ? 30.27511 13.56251  21.60057  1.000 46.55700  ? 207 GLU   A CA   1 
ATOM   3528 C  C    . GLU   A 1 207 ? 29.19542 12.50233  21.41324  1.000 49.87784  ? 207 GLU   A C    1 
ATOM   3529 O  O    . GLU   A 1 207 ? 28.02498 12.86255  21.23424  1.000 49.78105  ? 207 GLU   A O    1 
ATOM   3530 C  CB   . GLU   A 1 207 ? 30.37392 14.43035  20.34550  1.000 51.30146  ? 207 GLU   A CB   1 
ATOM   3531 C  CG   . GLU   A 1 207 ? 30.63145 13.68184  19.03924  1.000 43.63792  ? 207 GLU   A CG   1 
ATOM   3532 C  CD   . GLU   A 1 207 ? 32.10708 13.52168  18.72178  1.000 51.22217  ? 207 GLU   A CD   1 
ATOM   3533 O  OE1  . GLU   A 1 207 ? 32.91582 13.44713  19.67011  1.000 48.47841  ? 207 GLU   A OE1  1 
ATOM   3534 O  OE2  . GLU   A 1 207 ? 32.45729 13.46749  17.51482  1.000 48.56560  ? 207 GLU   A OE2  1 
ATOM   3535 H  H    . GLU   A 1 207 ? 32.17562 13.06271  21.32533  1.000 44.59153  ? 207 GLU   A H    1 
ATOM   3536 H  HA   . GLU   A 1 207 ? 30.00185 14.14038  22.33016  1.000 55.88268  ? 207 GLU   A HA   1 
ATOM   3537 H  HB2  . GLU   A 1 207 ? 29.53769 14.91078  20.24153  1.000 61.57602  ? 207 GLU   A HB2  1 
ATOM   3538 H  HB3  . GLU   A 1 207 ? 31.10402 15.05746  20.46628  1.000 61.57602  ? 207 GLU   A HB3  1 
ATOM   3539 H  HG2  . GLU   A 1 207 ? 30.24253 12.79551  19.10299  1.000 52.37978  ? 207 GLU   A HG2  1 
ATOM   3540 H  HG3  . GLU   A 1 207 ? 30.22134 14.17241  18.30982  1.000 52.37978  ? 207 GLU   A HG3  1 
ATOM   3541 N  N    . PHE   A 1 208 ? 29.55267 11.21835  21.45374  1.000 49.02733  ? 208 PHE   A N    1 
ATOM   3542 C  CA   . PHE   A 1 208 ? 28.57820 10.13825  21.34746  1.000 69.63951  ? 208 PHE   A CA   1 
ATOM   3543 C  C    . PHE   A 1 208 ? 28.55251 9.23229   22.57137  1.000 60.06195  ? 208 PHE   A C    1 
ATOM   3544 O  O    . PHE   A 1 208 ? 27.82321 8.23231   22.56702  1.000 57.24122  ? 208 PHE   A O    1 
ATOM   3545 C  CB   . PHE   A 1 208 ? 28.85523 9.28924   20.09444  1.000 63.13635  ? 208 PHE   A CB   1 
ATOM   3546 C  CG   . PHE   A 1 208 ? 28.90046 10.08642  18.82288  1.000 60.68257  ? 208 PHE   A CG   1 
ATOM   3547 C  CD1  . PHE   A 1 208 ? 27.76020 10.71215  18.33937  1.000 72.90825  ? 208 PHE   A CD1  1 
ATOM   3548 C  CD2  . PHE   A 1 208 ? 30.07723 10.20847  18.10871  1.000 55.87954  ? 208 PHE   A CD2  1 
ATOM   3549 C  CE1  . PHE   A 1 208 ? 27.79634 11.44908  17.16861  1.000 76.31067  ? 208 PHE   A CE1  1 
ATOM   3550 C  CE2  . PHE   A 1 208 ? 30.12032 10.94358  16.93353  1.000 59.05465  ? 208 PHE   A CE2  1 
ATOM   3551 C  CZ   . PHE   A 1 208 ? 28.97846 11.56552  16.46454  1.000 81.79442  ? 208 PHE   A CZ   1 
ATOM   3552 H  H    . PHE   A 1 208 ? 30.36367 10.94655  21.54327  1.000 58.84706  ? 208 PHE   A H    1 
ATOM   3553 H  HA   . PHE   A 1 208 ? 27.69664 10.53126  21.25104  1.000 83.58169  ? 208 PHE   A HA   1 
ATOM   3554 H  HB2  . PHE   A 1 208 ? 29.71341 8.84936   20.19900  1.000 75.77789  ? 208 PHE   A HB2  1 
ATOM   3555 H  HB3  . PHE   A 1 208 ? 28.15194 8.62730   20.00425  1.000 75.77789  ? 208 PHE   A HB3  1 
ATOM   3556 H  HD1  . PHE   A 1 208 ? 26.96087 10.63524  18.80847  1.000 87.50417  ? 208 PHE   A HD1  1 
ATOM   3557 H  HD2  . PHE   A 1 208 ? 30.84896 9.79298   18.41967  1.000 67.06972  ? 208 PHE   A HD2  1 
ATOM   3558 H  HE1  . PHE   A 1 208 ? 27.02551 11.86533  16.85643  1.000 91.58708  ? 208 PHE   A HE1  1 
ATOM   3559 H  HE2  . PHE   A 1 208 ? 30.91776 11.01811  16.46084  1.000 70.87985  ? 208 PHE   A HE2  1 
ATOM   3560 H  HZ   . PHE   A 1 208 ? 29.00627 12.06055  15.67773  1.000 98.16757  ? 208 PHE   A HZ   1 
ATOM   3561 N  N    . TRP   A 1 209 ? 29.32455 9.54636   23.61554  1.000 44.12964  ? 209 TRP   A N    1 
ATOM   3562 C  CA   . TRP   A 1 209 ? 29.29544 8.73277   24.82503  1.000 40.16678  ? 209 TRP   A CA   1 
ATOM   3563 C  C    . TRP   A 1 209 ? 27.90821 8.69718   25.45571  1.000 64.00847  ? 209 TRP   A C    1 
ATOM   3564 O  O    . TRP   A 1 209 ? 27.55832 7.72224   26.13167  1.000 59.93257  ? 209 TRP   A O    1 
ATOM   3565 C  CB   . TRP   A 1 209 ? 30.30339 9.26048   25.84325  1.000 39.33669  ? 209 TRP   A CB   1 
ATOM   3566 C  CG   . TRP   A 1 209 ? 31.73280 8.99932   25.48531  1.000 44.31414  ? 209 TRP   A CG   1 
ATOM   3567 C  CD1  . TRP   A 1 209 ? 32.20394 8.50838   24.29841  1.000 42.47177  ? 209 TRP   A CD1  1 
ATOM   3568 C  CD2  . TRP   A 1 209 ? 32.87794 9.19840   26.32005  1.000 43.69082  ? 209 TRP   A CD2  1 
ATOM   3569 N  NE1  . TRP   A 1 209 ? 33.57398 8.39467   24.34376  1.000 44.41064  ? 209 TRP   A NE1  1 
ATOM   3570 C  CE2  . TRP   A 1 209 ? 34.01315 8.81629   25.57111  1.000 47.61095  ? 209 TRP   A CE2  1 
ATOM   3571 C  CE3  . TRP   A 1 209 ? 33.05887 9.67454   27.62300  1.000 43.92542  ? 209 TRP   A CE3  1 
ATOM   3572 C  CZ2  . TRP   A 1 209 ? 35.30766 8.89056   26.08522  1.000 52.10006  ? 209 TRP   A CZ2  1 
ATOM   3573 C  CZ3  . TRP   A 1 209 ? 34.34262 9.74285   28.13076  1.000 51.95464  ? 209 TRP   A CZ3  1 
ATOM   3574 C  CH2  . TRP   A 1 209 ? 35.45049 9.35120   27.36608  1.000 53.97312  ? 209 TRP   A CH2  1 
ATOM   3575 H  H    . TRP   A 1 209 ? 29.86436 10.21515  23.64598  1.000 52.96984  ? 209 TRP   A H    1 
ATOM   3576 H  HA   . TRP   A 1 209 ? 29.54504 7.82720   24.58307  1.000 48.21441  ? 209 TRP   A HA   1 
ATOM   3577 H  HB2  . TRP   A 1 209 ? 30.19085 10.22072  25.92189  1.000 47.21829  ? 209 TRP   A HB2  1 
ATOM   3578 H  HB3  . TRP   A 1 209 ? 30.13208 8.83527   26.69809  1.000 47.21829  ? 209 TRP   A HB3  1 
ATOM   3579 H  HD1  . TRP   A 1 209 ? 31.67481 8.28412   23.56722  1.000 50.98039  ? 209 TRP   A HD1  1 
ATOM   3580 H  HE1  . TRP   A 1 209 ? 34.07335 8.10606   23.70585  1.000 53.30704  ? 209 TRP   A HE1  1 
ATOM   3581 H  HE3  . TRP   A 1 209 ? 32.33048 9.93961   28.13689  1.000 52.72477  ? 209 TRP   A HE3  1 
ATOM   3582 H  HZ2  . TRP   A 1 209 ? 36.04460 8.63708   25.57770  1.000 62.53434  ? 209 TRP   A HZ2  1 
ATOM   3583 H  HZ3  . TRP   A 1 209 ? 34.47408 10.05485  28.99694  1.000 62.35983  ? 209 TRP   A HZ3  1 
ATOM   3584 H  HH2  . TRP   A 1 209 ? 36.30138 9.40561   27.73744  1.000 64.78201  ? 209 TRP   A HH2  1 
ATOM   3585 N  N    . ASP   A 1 210 ? 27.11413 9.75371   25.27348  1.000 55.03724  ? 210 ASP   A N    1 
ATOM   3586 C  CA   . ASP   A 1 210 ? 25.77439 9.77486   25.84926  1.000 80.29437  ? 210 ASP   A CA   1 
ATOM   3587 C  C    . ASP   A 1 210 ? 24.84653 8.77652   25.16754  1.000 59.12470  ? 210 ASP   A C    1 
ATOM   3588 O  O    . ASP   A 1 210 ? 23.79328 8.44644   25.72328  1.000 63.76861  ? 210 ASP   A O    1 
ATOM   3589 C  CB   . ASP   A 1 210 ? 25.17463 11.18337  25.76226  1.000 79.00651  ? 210 ASP   A CB   1 
ATOM   3590 C  CG   . ASP   A 1 210 ? 24.77729 11.56603  24.34574  1.000 91.87671  ? 210 ASP   A CG   1 
ATOM   3591 O  OD1  . ASP   A 1 210 ? 25.52595 11.23242  23.39893  1.000 70.34707  ? 210 ASP   A OD1  1 
ATOM   3592 O  OD2  . ASP   A 1 210 ? 23.71107 12.19729  24.17472  1.000 65.17751  ? 210 ASP   A OD2  1 
ATOM   3593 H  H    . ASP   A 1 210 ? 27.32562 10.45809  24.82770  1.000 66.05895  ? 210 ASP   A H    1 
ATOM   3594 H  HA   . ASP   A 1 210 ? 25.83798 9.54079   26.78844  1.000 96.36751  ? 210 ASP   A HA   1 
ATOM   3595 H  HB2  . ASP   A 1 210 ? 24.38059 11.22382  26.31793  1.000 94.82208  ? 210 ASP   A HB2  1 
ATOM   3596 H  HB3  . ASP   A 1 210 ? 25.83074 11.82625  26.07390  1.000 94.82208  ? 210 ASP   A HB3  1 
ATOM   3597 N  N    . LYS   A 1 211 ? 25.20947 8.29607   23.97836  1.000 79.57213  ? 211 LYS   A N    1 
ATOM   3598 C  CA   A LYS   A 1 211 ? 24.43094 7.30650   23.24996  0.500 78.77756  ? 211 LYS   A CA   1 
ATOM   3599 C  CA   B LYS   A 1 211 ? 24.41095 7.30577   23.26994  0.500 78.78210  ? 211 LYS   A CA   1 
ATOM   3600 C  C    . LYS   A 1 211 ? 24.78578 5.87607   23.65059  1.000 81.47992  ? 211 LYS   A C    1 
ATOM   3601 O  O    . LYS   A 1 211 ? 24.40061 4.93475   22.94613  1.000 93.91918  ? 211 LYS   A O    1 
ATOM   3602 C  CB   A LYS   A 1 211 ? 24.63904 7.46641   21.73851  0.500 74.65772  ? 211 LYS   A CB   1 
ATOM   3603 C  CB   B LYS   A 1 211 ? 24.54380 7.50913   21.75753  0.500 74.73244  ? 211 LYS   A CB   1 
ATOM   3604 C  CG   A LYS   A 1 211 ? 24.64993 8.90334   21.22197  0.500 87.76590  ? 211 LYS   A CG   1 
ATOM   3605 C  CG   B LYS   A 1 211 ? 24.29117 8.95062   21.31835  0.500 88.58888  ? 211 LYS   A CG   1 
ATOM   3606 C  CD   A LYS   A 1 211 ? 23.26838 9.38841   20.79191  0.500 77.61284  ? 211 LYS   A CD   1 
ATOM   3607 C  CD   B LYS   A 1 211 ? 23.49217 9.04750   20.01837  0.500 71.68713  ? 211 LYS   A CD   1 
ATOM   3608 C  CE   A LYS   A 1 211 ? 22.36320 9.65094   21.98388  0.500 69.62645  ? 211 LYS   A CE   1 
ATOM   3609 C  CE   B LYS   A 1 211 ? 24.38382 9.03429   18.78265  0.500 64.47910  ? 211 LYS   A CE   1 
ATOM   3610 N  NZ   A LYS   A 1 211 ? 21.12592 10.37830  21.57337  0.500 65.22303  ? 211 LYS   A NZ   1 
ATOM   3611 N  NZ   B LYS   A 1 211 ? 24.90901 7.68224   18.45748  0.500 80.42500  ? 211 LYS   A NZ   1 
ATOM   3612 H  H    A LYS   A 1 211 ? 25.92375 8.53741   23.56464  0.500 95.50083  ? 211 LYS   A H    1 
ATOM   3613 H  H    B LYS   A 1 211 ? 25.92246 8.53316   23.55998  0.500 95.50083  ? 211 LYS   A H    1 
ATOM   3614 H  HA   A LYS   A 1 211 ? 23.49280 7.45985   23.44304  0.500 94.54734  ? 211 LYS   A HA   1 
ATOM   3615 H  HA   B LYS   A 1 211 ? 23.47830 7.43595   23.50258  0.500 94.55279  ? 211 LYS   A HA   1 
ATOM   3616 H  HB2  A LYS   A 1 211 ? 25.49288 7.06976   21.50499  0.500 89.60353  ? 211 LYS   A HB2  1 
ATOM   3617 H  HB2  B LYS   A 1 211 ? 25.44334 7.26795   21.48634  0.500 89.69319  ? 211 LYS   A HB2  1 
ATOM   3618 H  HB3  A LYS   A 1 211 ? 23.92104 7.00127   21.28132  0.500 89.60353  ? 211 LYS   A HB3  1 
ATOM   3619 H  HB3  B LYS   A 1 211 ? 23.89826 6.94249   21.30686  0.500 89.69319  ? 211 LYS   A HB3  1 
ATOM   3620 H  HG2  A LYS   A 1 211 ? 24.96727 9.49012   21.92617  0.500 105.33336 ? 211 LYS   A HG2  1 
ATOM   3621 H  HG2  B LYS   A 1 211 ? 23.79033 9.40854   22.01143  0.500 106.32093 ? 211 LYS   A HG2  1 
ATOM   3622 H  HG3  A LYS   A 1 211 ? 25.23912 8.95864   20.45340  0.500 105.33336 ? 211 LYS   A HG3  1 
ATOM   3623 H  HG3  B LYS   A 1 211 ? 25.14358 9.39191   21.17845  0.500 106.32093 ? 211 LYS   A HG3  1 
ATOM   3624 H  HD2  A LYS   A 1 211 ? 23.36071 10.21540  20.29345  0.500 93.14968  ? 211 LYS   A HD2  1 
ATOM   3625 H  HD2  B LYS   A 1 211 ? 22.88726 8.29144   19.96055  0.500 86.03882  ? 211 LYS   A HD2  1 
ATOM   3626 H  HD3  A LYS   A 1 211 ? 22.85025 8.71152   20.23704  0.500 93.14968  ? 211 LYS   A HD3  1 
ATOM   3627 H  HD3  B LYS   A 1 211 ? 22.98834 9.87638   20.01654  0.500 86.03882  ? 211 LYS   A HD3  1 
ATOM   3628 H  HE2  A LYS   A 1 211 ? 22.10336 8.80606   22.38331  0.500 83.56602  ? 211 LYS   A HE2  1 
ATOM   3629 H  HE2  B LYS   A 1 211 ? 23.87098 9.34634   18.02072  0.500 77.38919  ? 211 LYS   A HE2  1 
ATOM   3630 H  HE3  A LYS   A 1 211 ? 22.83599 10.19380  22.63402  0.500 83.56602  ? 211 LYS   A HE3  1 
ATOM   3631 H  HE3  B LYS   A 1 211 ? 25.14180 9.62015   18.93476  0.500 77.38919  ? 211 LYS   A HE3  1 
ATOM   3632 H  HZ1  A LYS   A 1 211 ? 20.60127 10.50950  22.28022  0.500 78.28191  ? 211 LYS   A HZ1  1 
ATOM   3633 H  HZ1  B LYS   A 1 211 ? 25.51112 7.73850   17.80448  0.500 96.52427  ? 211 LYS   A HZ1  1 
ATOM   3634 H  HZ2  A LYS   A 1 211 ? 21.33931 11.16749  21.22160  0.500 78.28191  ? 211 LYS   A HZ2  1 
ATOM   3635 H  HZ2  B LYS   A 1 211 ? 25.29431 7.32453   19.17560  0.500 96.52427  ? 211 LYS   A HZ2  1 
ATOM   3636 H  HZ3  A LYS   A 1 211 ? 20.68029 9.90286   20.96718  0.500 78.28191  ? 211 LYS   A HZ3  1 
ATOM   3637 H  HZ3  B LYS   A 1 211 ? 24.24425 7.15306   18.19259  0.500 96.52427  ? 211 LYS   A HZ3  1 
ATOM   3638 N  N    . ALA   A 1 212 ? 25.52077 5.69365   24.75131  1.000 54.96053  ? 212 ALA   A N    1 
ATOM   3639 C  CA   . ALA   A 1 212 ? 25.95978 4.37754   25.18390  1.000 60.12270  ? 212 ALA   A CA   1 
ATOM   3640 C  C    . ALA   A 1 212 ? 25.86690 4.27243   26.69658  1.000 66.71560  ? 212 ALA   A C    1 
ATOM   3641 O  O    . ALA   A 1 212 ? 26.07916 5.24935   27.41566  1.000 57.22848  ? 212 ALA   A O    1 
ATOM   3642 C  CB   . ALA   A 1 212 ? 27.39994 4.08382   24.74091  1.000 51.96519  ? 212 ALA   A CB   1 
ATOM   3643 H  H    . ALA   A 1 212 ? 25.77868 6.33080   25.26815  1.000 65.96691  ? 212 ALA   A H    1 
ATOM   3644 H  HA   . ALA   A 1 212 ? 25.37278 3.70945   24.79660  1.000 72.16151  ? 212 ALA   A HA   1 
ATOM   3645 H  HB1  . ALA   A 1 212 ? 27.65316 3.20160   25.05471  1.000 62.37250  ? 212 ALA   A HB1  1 
ATOM   3646 H  HB2  . ALA   A 1 212 ? 27.44526 4.11606   23.77250  1.000 62.37250  ? 212 ALA   A HB2  1 
ATOM   3647 H  HB3  . ALA   A 1 212 ? 27.99020 4.75253   25.12211  1.000 62.37250  ? 212 ALA   A HB3  1 
ATOM   3648 N  N    . ASP   A 1 213 ? 25.56655 3.06002   27.17223  1.000 47.74864  ? 213 ASP   A N    1 
ATOM   3649 C  CA   . ASP   A 1 213 ? 25.44377 2.81823   28.60400  1.000 45.23836  ? 213 ASP   A CA   1 
ATOM   3650 C  C    . ASP   A 1 213 ? 26.79771 2.73707   29.28884  1.000 48.88677  ? 213 ASP   A C    1 
ATOM   3651 O  O    . ASP   A 1 213 ? 26.91544 3.10948   30.46156  1.000 51.33640  ? 213 ASP   A O    1 
ATOM   3652 C  CB   . ASP   A 1 213 ? 24.65165 1.52755   28.84689  1.000 45.09359  ? 213 ASP   A CB   1 
ATOM   3653 C  CG   . ASP   A 1 213 ? 23.29248 1.54976   28.17541  1.000 66.57352  ? 213 ASP   A CG   1 
ATOM   3654 O  OD1  . ASP   A 1 213 ? 22.56110 2.54728   28.34923  1.000 58.64285  ? 213 ASP   A OD1  1 
ATOM   3655 O  OD2  . ASP   A 1 213 ? 22.95557 0.57947   27.46072  1.000 48.55816  ? 213 ASP   A OD2  1 
ATOM   3656 H  H    . ASP   A 1 213 ? 25.43003 2.36465   26.68496  1.000 57.31264  ? 213 ASP   A H    1 
ATOM   3657 H  HA   . ASP   A 1 213 ? 24.95390 3.55311   29.00510  1.000 54.30030  ? 213 ASP   A HA   1 
ATOM   3658 H  HB2  . ASP   A 1 213 ? 25.15161 0.77634   28.49102  1.000 54.12658  ? 213 ASP   A HB2  1 
ATOM   3659 H  HB3  . ASP   A 1 213 ? 24.51513 1.41337   29.80042  1.000 54.12658  ? 213 ASP   A HB3  1 
ATOM   3660 N  N    . PHE   A 1 214 ? 27.82161 2.25134   28.59146  1.000 38.58263  ? 214 PHE   A N    1 
ATOM   3661 C  CA   . PHE   A 1 214 ? 29.16622 2.16503   29.14058  1.000 33.41665  ? 214 PHE   A CA   1 
ATOM   3662 C  C    . PHE   A 1 214 ? 30.16059 2.52048   28.03911  1.000 40.99323  ? 214 PHE   A C    1 
ATOM   3663 O  O    . PHE   A 1 214 ? 29.90000 2.29429   26.85238  1.000 39.70947  ? 214 PHE   A O    1 
ATOM   3664 C  CB   . PHE   A 1 214 ? 29.51727 0.77467   29.67347  1.000 49.00794  ? 214 PHE   A CB   1 
ATOM   3665 C  CG   . PHE   A 1 214 ? 28.68867 0.33815   30.83713  1.000 51.82655  ? 214 PHE   A CG   1 
ATOM   3666 C  CD1  . PHE   A 1 214 ? 27.39613 -0.12257  30.65212  1.000 55.91339  ? 214 PHE   A CD1  1 
ATOM   3667 C  CD2  . PHE   A 1 214 ? 29.20541 0.37996   32.12308  1.000 55.45364  ? 214 PHE   A CD2  1 
ATOM   3668 C  CE1  . PHE   A 1 214 ? 26.62658 -0.52533  31.73335  1.000 58.93605  ? 214 PHE   A CE1  1 
ATOM   3669 C  CE2  . PHE   A 1 214 ? 28.44751 -0.02594  33.20001  1.000 62.43531  ? 214 PHE   A CE2  1 
ATOM   3670 C  CZ   . PHE   A 1 214 ? 27.15445 -0.47142  33.00762  1.000 52.48905  ? 214 PHE   A CZ   1 
ATOM   3671 H  H    . PHE   A 1 214 ? 27.75893 1.96112   27.78434  1.000 46.31343  ? 214 PHE   A H    1 
ATOM   3672 H  HA   . PHE   A 1 214 ? 29.23499 2.79139   29.87804  1.000 40.11425  ? 214 PHE   A HA   1 
ATOM   3673 H  HB2  . PHE   A 1 214 ? 29.38886 0.12815   28.96182  1.000 58.82380  ? 214 PHE   A HB2  1 
ATOM   3674 H  HB3  . PHE   A 1 214 ? 30.44494 0.77618   29.95690  1.000 58.82380  ? 214 PHE   A HB3  1 
ATOM   3675 H  HD1  . PHE   A 1 214 ? 27.04027 -0.16237  29.79381  1.000 67.11033  ? 214 PHE   A HD1  1 
ATOM   3676 H  HD2  . PHE   A 1 214 ? 30.07307 0.68529   32.26034  1.000 66.55864  ? 214 PHE   A HD2  1 
ATOM   3677 H  HE1  . PHE   A 1 214 ? 25.75823 -0.83056  31.60035  1.000 70.73753  ? 214 PHE   A HE1  1 
ATOM   3678 H  HE2  . PHE   A 1 214 ? 28.80712 0.00013   34.05728  1.000 74.93665  ? 214 PHE   A HE2  1 
ATOM   3679 H  HZ   . PHE   A 1 214 ? 26.63979 -0.73486  33.73606  1.000 63.00113  ? 214 PHE   A HZ   1 
ATOM   3680 N  N    . ILE   A 1 215 ? 31.31254 3.05694   28.44118  1.000 44.85445  ? 215 ILE   A N    1 
ATOM   3681 C  CA   . ILE   A 1 215 ? 32.38948 3.39541   27.51798  1.000 44.76578  ? 215 ILE   A CA   1 
ATOM   3682 C  C    . ILE   A 1 215 ? 33.66763 2.74960   28.03159  1.000 38.27838  ? 215 ILE   A C    1 
ATOM   3683 O  O    . ILE   A 1 215 ? 34.00552 2.88521   29.21369  1.000 50.84217  ? 215 ILE   A O    1 
ATOM   3684 C  CB   . ILE   A 1 215 ? 32.57388 4.92058   27.38626  1.000 46.74253  ? 215 ILE   A CB   1 
ATOM   3685 C  CG1  . ILE   A 1 215 ? 31.30218 5.57845   26.85390  1.000 51.13390  ? 215 ILE   A CG1  1 
ATOM   3686 C  CG2  . ILE   A 1 215 ? 33.75366 5.22588   26.46169  1.000 60.98459  ? 215 ILE   A CG2  1 
ATOM   3687 C  CD1  . ILE   A 1 215 ? 30.29183 5.93182   27.92764  1.000 62.48325  ? 215 ILE   A CD1  1 
ATOM   3688 H  H    . ILE   A 1 215 ? 31.49507 3.23700   29.26207  1.000 53.83962  ? 215 ILE   A H    1 
ATOM   3689 H  HA   . ILE   A 1 215 ? 32.18841 3.03577   26.63984  1.000 53.73321  ? 215 ILE   A HA   1 
ATOM   3690 H  HB   . ILE   A 1 215 ? 32.75619 5.28215   28.26769  1.000 56.10531  ? 215 ILE   A HB   1 
ATOM   3691 H  HG12 . ILE   A 1 215 ? 31.54494 6.39865   26.39646  1.000 61.37495  ? 215 ILE   A HG12 1 
ATOM   3692 H  HG13 . ILE   A 1 215 ? 30.87253 4.96788   26.23462  1.000 61.37495  ? 215 ILE   A HG13 1 
ATOM   3693 H  HG21 . ILE   A 1 215 ? 33.74660 6.17069   26.24218  1.000 73.19578  ? 215 ILE   A HG21 1 
ATOM   3694 H  HG22 . ILE   A 1 215 ? 34.57915 4.99833   26.91742  1.000 73.19578  ? 215 ILE   A HG22 1 
ATOM   3695 H  HG23 . ILE   A 1 215 ? 33.66592 4.69770   25.65284  1.000 73.19578  ? 215 ILE   A HG23 1 
ATOM   3696 H  HD11 . ILE   A 1 215 ? 29.72977 6.65438   27.60688  1.000 74.99417  ? 215 ILE   A HD11 1 
ATOM   3697 H  HD12 . ILE   A 1 215 ? 29.74926 5.15109   28.11995  1.000 74.99417  ? 215 ILE   A HD12 1 
ATOM   3698 H  HD13 . ILE   A 1 215 ? 30.76510 6.21080   28.72707  1.000 74.99417  ? 215 ILE   A HD13 1 
ATOM   3699 N  N    . VAL   A 1 216 ? 34.37895 2.05225   27.15043  1.000 36.72695  ? 216 VAL   A N    1 
ATOM   3700 C  CA   . VAL   A 1 216 ? 35.65153 1.43683   27.48891  1.000 35.37732  ? 216 VAL   A CA   1 
ATOM   3701 C  C    . VAL   A 1 216 ? 36.69513 1.83053   26.45469  1.000 43.45248  ? 216 VAL   A C    1 
ATOM   3702 O  O    . VAL   A 1 216 ? 36.37821 2.24259   25.33601  1.000 45.47288  ? 216 VAL   A O    1 
ATOM   3703 C  CB   . VAL   A 1 216 ? 35.55284 -0.10436  27.58821  1.000 45.37162  ? 216 VAL   A CB   1 
ATOM   3704 C  CG1  . VAL   A 1 216 ? 34.43570 -0.50643  28.55137  1.000 45.12607  ? 216 VAL   A CG1  1 
ATOM   3705 C  CG2  . VAL   A 1 216 ? 35.32697 -0.72587  26.21276  1.000 42.28336  ? 216 VAL   A CG2  1 
ATOM   3706 H  H    . VAL   A 1 216 ? 34.13783 1.92098   26.33543  1.000 44.08661  ? 216 VAL   A H    1 
ATOM   3707 H  HA   . VAL   A 1 216 ? 35.94046 1.78114   28.34849  1.000 42.46705  ? 216 VAL   A HA   1 
ATOM   3708 H  HB   . VAL   A 1 216 ? 36.39184 -0.44683  27.93418  1.000 54.46021  ? 216 VAL   A HB   1 
ATOM   3709 H  HG11 . VAL   A 1 216 ? 34.44670 -1.46991  28.66319  1.000 54.16555  ? 216 VAL   A HG11 1 
ATOM   3710 H  HG12 . VAL   A 1 216 ? 34.58427 -0.07252  29.40610  1.000 54.16555  ? 216 VAL   A HG12 1 
ATOM   3711 H  HG13 . VAL   A 1 216 ? 33.58387 -0.22604  28.18169  1.000 54.16555  ? 216 VAL   A HG13 1 
ATOM   3712 H  HG21 . VAL   A 1 216 ? 35.02852 -1.64193  26.32530  1.000 50.75430  ? 216 VAL   A HG21 1 
ATOM   3713 H  HG22 . VAL   A 1 216 ? 34.65141 -0.21339  25.74172  1.000 50.75430  ? 216 VAL   A HG22 1 
ATOM   3714 H  HG23 . VAL   A 1 216 ? 36.16077 -0.70811  25.71742  1.000 50.75430  ? 216 VAL   A HG23 1 
ATOM   3715 N  N    . SER   A 1 217 ? 37.96189 1.69673   26.85405  1.000 48.17184  ? 217 SER   A N    1 
ATOM   3716 C  CA   . SER   A 1 217 ? 39.09340 1.85397   25.95071  1.000 43.75998  ? 217 SER   A CA   1 
ATOM   3717 C  C    . SER   A 1 217 ? 39.90165 0.58008   25.79555  1.000 37.65737  ? 217 SER   A C    1 
ATOM   3718 O  O    . SER   A 1 217 ? 40.79338 0.53190   24.94016  1.000 53.10674  ? 217 SER   A O    1 
ATOM   3719 C  CB   . SER   A 1 217 ? 40.02248 2.98039   26.43835  1.000 47.40185  ? 217 SER   A CB   1 
ATOM   3720 O  OG   . SER   A 1 217 ? 40.48869 2.71394   27.75048  1.000 47.96997  ? 217 SER   A OG   1 
ATOM   3721 H  H    . SER   A 1 217 ? 38.19231 1.51100   27.66152  1.000 57.82047  ? 217 SER   A H    1 
ATOM   3722 H  HA   . SER   A 1 217 ? 38.76467 2.11335   25.07575  1.000 52.52625  ? 217 SER   A HA   1 
ATOM   3723 H  HB2  . SER   A 1 217 ? 40.78290 3.04451   25.83956  1.000 56.89649  ? 217 SER   A HB2  1 
ATOM   3724 H  HB3  . SER   A 1 217 ? 39.53099 3.81665   26.44118  1.000 56.89649  ? 217 SER   A HB3  1 
ATOM   3725 H  HG   . SER   A 1 217 ? 41.00246 3.32858   28.00317  1.000 57.57823  ? 217 SER   A HG   1 
ATOM   3726 N  N    . ASP   A 1 218 ? 39.61733 -0.44984  26.59071  1.000 39.47720  ? 218 ASP   A N    1 
ATOM   3727 C  CA   . ASP   A 1 218 ? 40.25945 -1.75229  26.49646  1.000 42.85869  ? 218 ASP   A CA   1 
ATOM   3728 C  C    . ASP   A 1 218 ? 39.17423 -2.81107  26.65506  1.000 42.79110  ? 218 ASP   A C    1 
ATOM   3729 O  O    . ASP   A 1 218 ? 38.29828 -2.68487  27.51280  1.000 42.35188  ? 218 ASP   A O    1 
ATOM   3730 C  CB   . ASP   A 1 218 ? 41.34668 -1.90513  27.55592  1.000 43.83370  ? 218 ASP   A CB   1 
ATOM   3731 C  CG   . ASP   A 1 218 ? 42.02889 -3.25218  27.50254  1.000 46.99886  ? 218 ASP   A CG   1 
ATOM   3732 O  OD1  . ASP   A 1 218 ? 41.34715 -4.26907  27.74297  1.000 53.44341  ? 218 ASP   A OD1  1 
ATOM   3733 O  OD2  . ASP   A 1 218 ? 43.24709 -3.29579  27.22249  1.000 67.65150  ? 218 ASP   A OD2  1 
ATOM   3734 H  H    . ASP   A 1 218 ? 39.03047 -0.41425  27.21835  1.000 47.38691  ? 218 ASP   A H    1 
ATOM   3735 H  HA   . ASP   A 1 218 ? 40.68579 -1.87764  25.63424  1.000 51.44470  ? 218 ASP   A HA   1 
ATOM   3736 H  HB2  . ASP   A 1 218 ? 42.02099 -1.22165  27.41785  1.000 52.61471  ? 218 ASP   A HB2  1 
ATOM   3737 H  HB3  . ASP   A 1 218 ? 40.94815 -1.80528  28.43461  1.000 52.61471  ? 218 ASP   A HB3  1 
ATOM   3738 N  N    A LEU   A 1 219 ? 39.23814 -3.85244  25.82235  0.440 37.69522  ? 219 LEU   A N    1 
ATOM   3739 N  N    B LEU   A 1 219 ? 39.22840 -3.85164  25.82020  0.560 37.59841  ? 219 LEU   A N    1 
ATOM   3740 C  CA   A LEU   A 1 219 ? 38.19227 -4.86778  25.83494  0.440 39.64997  ? 219 LEU   A CA   1 
ATOM   3741 C  CA   B LEU   A 1 219 ? 38.17522 -4.86100  25.84726  0.560 39.73862  ? 219 LEU   A CA   1 
ATOM   3742 C  C    A LEU   A 1 219 ? 38.17528 -5.66868  27.13351  0.440 40.57706  ? 219 LEU   A C    1 
ATOM   3743 C  C    B LEU   A 1 219 ? 38.17220 -5.67081  27.14114  0.560 40.57021  ? 219 LEU   A C    1 
ATOM   3744 O  O    A LEU   A 1 219 ? 37.14656 -6.26971  27.46324  0.440 34.61996  ? 219 LEU   A O    1 
ATOM   3745 O  O    B LEU   A 1 219 ? 37.15127 -6.28479  27.47197  0.560 34.53447  ? 219 LEU   A O    1 
ATOM   3746 C  CB   A LEU   A 1 219 ? 38.36249 -5.81541  24.65324  0.440 37.81475  ? 219 LEU   A CB   1 
ATOM   3747 C  CB   B LEU   A 1 219 ? 38.31306 -5.80534  24.65960  0.560 37.66707  ? 219 LEU   A CB   1 
ATOM   3748 C  CG   A LEU   A 1 219 ? 37.07015 -6.20247  23.93645  0.440 37.59738  ? 219 LEU   A CG   1 
ATOM   3749 C  CG   B LEU   A 1 219 ? 38.06663 -5.14424  23.30348  0.560 32.29698  ? 219 LEU   A CG   1 
ATOM   3750 C  CD1  A LEU   A 1 219 ? 36.43640 -4.98888  23.27507  0.440 33.57472  ? 219 LEU   A CD1  1 
ATOM   3751 C  CD1  B LEU   A 1 219 ? 38.40076 -6.10734  22.17844  0.560 34.22347  ? 219 LEU   A CD1  1 
ATOM   3752 C  CD2  A LEU   A 1 219 ? 37.32826 -7.29920  22.92515  0.440 39.04115  ? 219 LEU   A CD2  1 
ATOM   3753 C  CD2  B LEU   A 1 219 ? 36.63000 -4.65566  23.19342  0.560 41.12694  ? 219 LEU   A CD2  1 
ATOM   3754 H  H    A LEU   A 1 219 ? 39.86661 -3.98941  25.25150  0.440 45.24854  ? 219 LEU   A H    1 
ATOM   3755 H  H    B LEU   A 1 219 ? 39.85051 -3.99101  25.24302  0.560 45.13236  ? 219 LEU   A H    1 
ATOM   3756 H  HA   A LEU   A 1 219 ? 37.33471 -4.42370  25.74385  0.440 47.59424  ? 219 LEU   A HA   1 
ATOM   3757 H  HA   B LEU   A 1 219 ? 37.32160 -4.40616  25.77419  0.560 47.70061  ? 219 LEU   A HA   1 
ATOM   3758 H  HB2  A LEU   A 1 219 ? 38.93992 -5.38908  24.00076  0.440 45.39197  ? 219 LEU   A HB2  1 
ATOM   3759 H  HB2  B LEU   A 1 219 ? 39.21374 -6.16540  24.65314  0.560 45.21476  ? 219 LEU   A HB2  1 
ATOM   3760 H  HB3  A LEU   A 1 219 ? 38.77249 -6.63362  24.97467  0.440 45.39197  ? 219 LEU   A HB3  1 
ATOM   3761 H  HB3  B LEU   A 1 219 ? 37.66919 -6.52399  24.75901  0.560 45.21476  ? 219 LEU   A HB3  1 
ATOM   3762 H  HG   A LEU   A 1 219 ? 36.43916 -6.54452  24.58895  0.440 45.13113  ? 219 LEU   A HG   1 
ATOM   3763 H  HG   B LEU   A 1 219 ? 38.64555 -4.37064  23.21812  0.560 38.77065  ? 219 LEU   A HG   1 
ATOM   3764 H  HD11 A LEU   A 1 219 ? 35.80409 -5.28933  22.60364  0.440 40.30393  ? 219 LEU   A HD11 1 
ATOM   3765 H  HD11 B LEU   A 1 219 ? 38.25615 -5.66260  21.32862  0.560 41.08243  ? 219 LEU   A HD11 1 
ATOM   3766 H  HD12 A LEU   A 1 219 ? 35.97781 -4.46474  23.95026  0.440 40.30393  ? 219 LEU   A HD12 1 
ATOM   3767 H  HD12 B LEU   A 1 219 ? 39.32960 -6.37543  22.25764  0.560 41.08243  ? 219 LEU   A HD12 1 
ATOM   3768 H  HD13 A LEU   A 1 219 ? 37.13240 -4.45638  22.85922  0.440 40.30393  ? 219 LEU   A HD13 1 
ATOM   3769 H  HD13 B LEU   A 1 219 ? 37.82503 -6.88498  22.24700  0.560 41.08243  ? 219 LEU   A HD13 1 
ATOM   3770 H  HD21 A LEU   A 1 219 ? 36.50585 -7.48726  22.44642  0.440 46.86365  ? 219 LEU   A HD21 1 
ATOM   3771 H  HD21 B LEU   A 1 219 ? 36.43493 -4.45508  22.26464  0.560 49.36660  ? 219 LEU   A HD21 1 
ATOM   3772 H  HD22 A LEU   A 1 219 ? 38.01176 -7.00189  22.30439  0.440 46.86365  ? 219 LEU   A HD22 1 
ATOM   3773 H  HD22 B LEU   A 1 219 ? 36.03449 -5.35111  23.51376  0.560 49.36660  ? 219 LEU   A HD22 1 
ATOM   3774 H  HD23 A LEU   A 1 219 ? 37.62868 -8.09474  23.39179  0.440 46.86365  ? 219 LEU   A HD23 1 
ATOM   3775 H  HD23 B LEU   A 1 219 ? 36.52597 -3.85654  23.73331  0.560 49.36660  ? 219 LEU   A HD23 1 
ATOM   3776 N  N    . ARG   A 1 220 ? 39.28596 -5.70068  27.86953  1.000 37.86196  ? 220 ARG   A N    1 
ATOM   3777 C  CA   . ARG   A 1 220 ? 39.29082 -6.38810  29.16315  1.000 43.04679  ? 220 ARG   A CA   1 
ATOM   3778 C  C    . ARG   A 1 220 ? 38.36779 -5.71961  30.17299  1.000 45.80921  ? 220 ARG   A C    1 
ATOM   3779 O  O    . ARG   A 1 220 ? 38.00931 -6.34589  31.17433  1.000 42.61319  ? 220 ARG   A O    1 
ATOM   3780 C  CB   . ARG   A 1 220 ? 40.71545 -6.46877  29.70393  1.000 45.88684  ? 220 ARG   A CB   1 
ATOM   3781 C  CG   . ARG   A 1 220 ? 41.56122 -7.52018  28.98592  1.000 44.13179  ? 220 ARG   A CG   1 
ATOM   3782 C  CD   . ARG   A 1 220 ? 43.04145 -7.37283  29.29322  1.000 45.49681  ? 220 ARG   A CD   1 
ATOM   3783 N  NE   . ARG   A 1 220 ? 43.60405 -6.17817  28.68020  1.000 52.85802  ? 220 ARG   A NE   1 
ATOM   3784 C  CZ   . ARG   A 1 220 ? 44.85951 -5.77912  28.82244  1.000 78.81644  ? 220 ARG   A CZ   1 
ATOM   3785 N  NH1  . ARG   A 1 220 ? 45.71278 -6.44392  29.58331  1.000 88.45394  ? 220 ARG   A NH1  1 
ATOM   3786 N  NH2  . ARG   A 1 220 ? 45.26934 -4.68634  28.18222  1.000 69.41675  ? 220 ARG   A NH2  1 
ATOM   3787 H  H    A ARG   A 1 220 ? 40.03498 -5.34033  27.64882  0.440 45.44862  ? 220 ARG   A H    1 
ATOM   3788 H  H    B ARG   A 1 220 ? 40.03418 -5.34076  27.64542  0.560 45.44862  ? 220 ARG   A H    1 
ATOM   3789 H  HA   . ARG   A 1 220 ? 38.97487 -7.29706  29.04127  1.000 51.67042  ? 220 ARG   A HA   1 
ATOM   3790 H  HB2  . ARG   A 1 220 ? 41.14601 -5.60719  29.58912  1.000 55.07848  ? 220 ARG   A HB2  1 
ATOM   3791 H  HB3  . ARG   A 1 220 ? 40.68319 -6.70073  30.64523  1.000 55.07848  ? 220 ARG   A HB3  1 
ATOM   3792 H  HG2  . ARG   A 1 220 ? 41.28022 -8.40390  29.27048  1.000 52.97242  ? 220 ARG   A HG2  1 
ATOM   3793 H  HG3  . ARG   A 1 220 ? 41.44084 -7.42620  28.02801  1.000 52.97242  ? 220 ARG   A HG3  1 
ATOM   3794 H  HD2  . ARG   A 1 220 ? 43.16412 -7.30831  30.25327  1.000 54.61045  ? 220 ARG   A HD2  1 
ATOM   3795 H  HD3  . ARG   A 1 220 ? 43.51812 -8.14430  28.94896  1.000 54.61045  ? 220 ARG   A HD3  1 
ATOM   3796 H  HE   . ARG   A 1 220 ? 43.08489 -5.69754  28.19125  1.000 63.44390  ? 220 ARG   A HE   1 
ATOM   3797 H  HH11 . ARG   A 1 220 ? 45.45689 -7.15195  29.99903  1.000 106.15899 ? 220 ARG   A HH11 1 
ATOM   3798 H  HH12 . ARG   A 1 220 ? 46.52353 -6.16821  29.66238  1.000 106.15899 ? 220 ARG   A HH12 1 
ATOM   3799 H  HH21 . ARG   A 1 220 ? 44.72154 -4.24901  27.68396  1.000 83.31437  ? 220 ARG   A HH21 1 
ATOM   3800 H  HH22 . ARG   A 1 220 ? 46.08190 -4.41769  28.26687  1.000 83.31437  ? 220 ARG   A HH22 1 
ATOM   3801 N  N    . GLU   A 1 221 ? 37.96019 -4.47102  29.93035  1.000 40.31574  ? 221 GLU   A N    1 
ATOM   3802 C  CA   . GLU   A 1 221 ? 36.95533 -3.85654  30.78802  1.000 42.65195  ? 221 GLU   A CA   1 
ATOM   3803 C  C    . GLU   A 1 221 ? 35.57943 -4.49632  30.61254  1.000 55.15486  ? 221 GLU   A C    1 
ATOM   3804 O  O    . GLU   A 1 221 ? 34.70969 -4.32862  31.46858  1.000 40.40865  ? 221 GLU   A O    1 
ATOM   3805 C  CB   . GLU   A 1 221 ? 36.83592 -2.36217  30.49811  1.000 49.36774  ? 221 GLU   A CB   1 
ATOM   3806 C  CG   . GLU   A 1 221 ? 38.13070 -1.57300  30.62767  1.000 60.68727  ? 221 GLU   A CG   1 
ATOM   3807 C  CD   . GLU   A 1 221 ? 37.92625 -0.09710  30.31741  1.000 68.10008  ? 221 GLU   A CD   1 
ATOM   3808 O  OE1  . GLU   A 1 221 ? 37.03025 0.52133   30.93360  1.000 75.87607  ? 221 GLU   A OE1  1 
ATOM   3809 O  OE2  . GLU   A 1 221 ? 38.64050 0.43548   29.43972  1.000 60.48515  ? 221 GLU   A OE2  1 
ATOM   3810 H  H    . GLU   A 1 221 ? 38.24522 -3.97300  29.28977  1.000 48.39315  ? 221 GLU   A H    1 
ATOM   3811 H  HA   . GLU   A 1 221 ? 37.24281 -3.96739  31.70778  1.000 51.19661  ? 221 GLU   A HA   1 
ATOM   3812 H  HB2  . GLU   A 1 221 ? 36.51803 -2.25095  29.58845  1.000 59.25556  ? 221 GLU   A HB2  1 
ATOM   3813 H  HB3  . GLU   A 1 221 ? 36.19893 -1.97907  31.12131  1.000 59.25556  ? 221 GLU   A HB3  1 
ATOM   3814 H  HG2  . GLU   A 1 221 ? 38.46240 -1.64962  31.53597  1.000 72.83899  ? 221 GLU   A HG2  1 
ATOM   3815 H  HG3  . GLU   A 1 221 ? 38.78461 -1.92688  30.00472  1.000 72.83899  ? 221 GLU   A HG3  1 
ATOM   3816 N  N    . VAL   A 1 222 ? 35.35468 -5.21894  29.51594  1.000 39.71304  ? 222 VAL   A N    1 
ATOM   3817 C  CA   . VAL   A 1 222 ? 34.01667 -5.72931  29.23405  1.000 36.64141  ? 222 VAL   A CA   1 
ATOM   3818 C  C    . VAL   A 1 222 ? 33.60601 -6.76480  30.27133  1.000 34.33888  ? 222 VAL   A C    1 
ATOM   3819 O  O    . VAL   A 1 222 ? 32.47738 -6.73991  30.77156  1.000 39.62664  ? 222 VAL   A O    1 
ATOM   3820 C  CB   . VAL   A 1 222 ? 33.94924 -6.29504  27.79960  1.000 38.11482  ? 222 VAL   A CB   1 
ATOM   3821 C  CG1  . VAL   A 1 222 ? 32.64491 -7.03931  27.58133  1.000 37.86152  ? 222 VAL   A CG1  1 
ATOM   3822 C  CG2  . VAL   A 1 222 ? 34.09757 -5.15555  26.79683  1.000 35.11528  ? 222 VAL   A CG2  1 
ATOM   3823 H  H    . VAL   A 1 222 ? 35.94955 -5.42396  28.92968  1.000 47.66992  ? 222 VAL   A H    1 
ATOM   3824 H  HA   . VAL   A 1 222 ? 33.38848 -4.99261  29.29361  1.000 43.98396  ? 222 VAL   A HA   1 
ATOM   3825 H  HB   . VAL   A 1 222 ? 34.67347 -6.92594  27.66410  1.000 45.75206  ? 222 VAL   A HB   1 
ATOM   3826 H  HG11 . VAL   A 1 222 ? 32.49511 -7.14123  26.62841  1.000 45.44810  ? 222 VAL   A HG11 1 
ATOM   3827 H  HG12 . VAL   A 1 222 ? 32.70472 -7.91135  28.00190  1.000 45.44810  ? 222 VAL   A HG12 1 
ATOM   3828 H  HG13 . VAL   A 1 222 ? 31.92060 -6.53002  27.97743  1.000 45.44810  ? 222 VAL   A HG13 1 
ATOM   3829 H  HG21 . VAL   A 1 222 ? 34.06178 -5.51902  25.89821  1.000 42.15261  ? 222 VAL   A HG21 1 
ATOM   3830 H  HG22 . VAL   A 1 222 ? 33.37312 -4.52383  26.92722  1.000 42.15261  ? 222 VAL   A HG22 1 
ATOM   3831 H  HG23 . VAL   A 1 222 ? 34.94994 -4.71595  26.94213  1.000 42.15261  ? 222 VAL   A HG23 1 
ATOM   3832 N  N    . ILE   A 1 223 ? 34.50075 -7.69714  30.60263  1.000 39.04978  ? 223 ILE   A N    1 
ATOM   3833 C  CA   . ILE   A 1 223 ? 34.13083 -8.74512  31.55118  1.000 45.60499  ? 223 ILE   A CA   1 
ATOM   3834 C  C    . ILE   A 1 223 ? 33.79789 -8.13565  32.90912  1.000 48.17231  ? 223 ILE   A C    1 
ATOM   3835 O  O    . ILE   A 1 223 ? 32.87402 -8.58431  33.59936  1.000 46.33601  ? 223 ILE   A O    1 
ATOM   3836 C  CB   . ILE   A 1 223 ? 35.24711 -9.80224  31.66499  1.000 54.00188  ? 223 ILE   A CB   1 
ATOM   3837 C  CG1  . ILE   A 1 223 ? 34.61628 -11.16231 32.01303  1.000 89.45313  ? 223 ILE   A CG1  1 
ATOM   3838 C  CG2  . ILE   A 1 223 ? 36.27870 -9.40360  32.70589  1.000 78.49990  ? 223 ILE   A CG2  1 
ATOM   3839 C  CD1  . ILE   A 1 223 ? 35.60383 -12.26276 32.36616  1.000 72.40242  ? 223 ILE   A CD1  1 
ATOM   3840 H  H    . ILE   A 1 223 ? 35.30480 -7.74363  30.30107  1.000 46.87401  ? 223 ILE   A H    1 
ATOM   3841 H  HA   . ILE   A 1 223 ? 33.33789 -9.19122  31.21482  1.000 54.74026  ? 223 ILE   A HA   1 
ATOM   3842 H  HB   . ILE   A 1 223 ? 35.70641 -9.86643  30.81304  1.000 64.81653  ? 223 ILE   A HB   1 
ATOM   3843 H  HG12 . ILE   A 1 223 ? 34.03109 -11.04188 32.77720  1.000 107.35803 ? 223 ILE   A HG12 1 
ATOM   3844 H  HG13 . ILE   A 1 223 ? 34.10411 -11.46714 31.24774  1.000 107.35803 ? 223 ILE   A HG13 1 
ATOM   3845 H  HG21 . ILE   A 1 223 ? 37.00966 -10.04095 32.68633  1.000 94.21416  ? 223 ILE   A HG21 1 
ATOM   3846 H  HG22 . ILE   A 1 223 ? 36.60883 -8.51522  32.49926  1.000 94.21416  ? 223 ILE   A HG22 1 
ATOM   3847 H  HG23 . ILE   A 1 223 ? 35.86113 -9.40596  33.58140  1.000 94.21416  ? 223 ILE   A HG23 1 
ATOM   3848 H  HD11 . ILE   A 1 223 ? 35.11747 -13.08992 32.50811  1.000 86.89718  ? 223 ILE   A HD11 1 
ATOM   3849 H  HD12 . ILE   A 1 223 ? 36.23215 -12.36978 31.63496  1.000 86.89718  ? 223 ILE   A HD12 1 
ATOM   3850 H  HD13 . ILE   A 1 223 ? 36.07732 -12.01438 33.17548  1.000 86.89718  ? 223 ILE   A HD13 1 
ATOM   3851 N  N    . LYS   A 1 224 ? 34.54321 -7.10356  33.31055  1.000 47.75115  ? 224 LYS   A N    1 
ATOM   3852 C  CA   A LYS   A 1 224 ? 34.29068 -6.46789  34.59812  0.600 58.26511  ? 224 LYS   A CA   1 
ATOM   3853 C  CA   B LYS   A 1 224 ? 34.29406 -6.46287  34.59594  0.400 58.22368  ? 224 LYS   A CA   1 
ATOM   3854 C  C    . LYS   A 1 224 ? 32.91994 -5.80611  34.62113  1.000 50.23634  ? 224 LYS   A C    1 
ATOM   3855 O  O    . LYS   A 1 224 ? 32.23284 -5.82283  35.64725  1.000 52.51358  ? 224 LYS   A O    1 
ATOM   3856 C  CB   A LYS   A 1 224 ? 35.39635 -5.45398  34.90566  0.600 50.86040  ? 224 LYS   A CB   1 
ATOM   3857 C  CB   B LYS   A 1 224 ? 35.38592 -5.43243  34.88573  0.400 50.82306  ? 224 LYS   A CB   1 
ATOM   3858 C  CG   A LYS   A 1 224 ? 36.79869 -6.06597  34.90875  0.600 61.44651  ? 224 LYS   A CG   1 
ATOM   3859 C  CG   B LYS   A 1 224 ? 36.78012 -6.02210  35.08872  0.400 60.79706  ? 224 LYS   A CG   1 
ATOM   3860 C  CD   A LYS   A 1 224 ? 37.80183 -5.24235  35.71823  0.600 60.65098  ? 224 LYS   A CD   1 
ATOM   3861 C  CD   B LYS   A 1 224 ? 36.93901 -6.64540  36.47075  0.400 57.36004  ? 224 LYS   A CD   1 
ATOM   3862 C  CE   A LYS   A 1 224 ? 38.64678 -4.32298  34.84314  0.600 52.89664  ? 224 LYS   A CE   1 
ATOM   3863 C  CE   B LYS   A 1 224 ? 36.55663 -8.11821  36.48070  0.400 49.41388  ? 224 LYS   A CE   1 
ATOM   3864 N  NZ   A LYS   A 1 224 ? 37.88807 -3.14275  34.33571  0.600 76.49753  ? 224 LYS   A NZ   1 
ATOM   3865 N  NZ   B LYS   A 1 224 ? 35.81184 -8.48022  37.72364  0.400 39.57555  ? 224 LYS   A NZ   1 
ATOM   3866 H  H    A LYS   A 1 224 ? 35.19074 -6.75911  32.86149  0.600 57.31566  ? 224 LYS   A H    1 
ATOM   3867 H  H    B LYS   A 1 224 ? 35.19123 -6.76076  32.86093  0.400 57.31566  ? 224 LYS   A H    1 
ATOM   3868 H  HA   A LYS   A 1 224 ? 34.30610 -7.14219  35.29524  0.600 69.93240  ? 224 LYS   A HA   1 
ATOM   3869 H  HA   B LYS   A 1 224 ? 34.32143 -7.13509  35.29471  0.400 69.88269  ? 224 LYS   A HA   1 
ATOM   3870 H  HB2  A LYS   A 1 224 ? 35.37760 -4.75627  34.23205  0.600 61.04675  ? 224 LYS   A HB2  1 
ATOM   3871 H  HB2  B LYS   A 1 224 ? 35.43499 -4.81654  34.13795  0.400 61.00194  ? 224 LYS   A HB2  1 
ATOM   3872 H  HB3  A LYS   A 1 224 ? 35.23619 -5.07249  35.78299  0.600 61.04675  ? 224 LYS   A HB3  1 
ATOM   3873 H  HB3  B LYS   A 1 224 ? 35.15047 -4.95306  35.69546  0.400 61.00194  ? 224 LYS   A HB3  1 
ATOM   3874 H  HG2  A LYS   A 1 224 ? 36.75597 -6.95323  35.29841  0.600 73.75008  ? 224 LYS   A HG2  1 
ATOM   3875 H  HG2  B LYS   A 1 224 ? 36.93485 -6.71261  34.42528  0.400 72.97074  ? 224 LYS   A HG2  1 
ATOM   3876 H  HG3  A LYS   A 1 224 ? 37.12259 -6.11972  33.99601  0.600 73.75008  ? 224 LYS   A HG3  1 
ATOM   3877 H  HG3  B LYS   A 1 224 ? 37.44139 -5.31856  34.99576  0.400 72.97074  ? 224 LYS   A HG3  1 
ATOM   3878 H  HD2  A LYS   A 1 224 ? 37.31960 -4.69140  36.35447  0.600 72.79545  ? 224 LYS   A HD2  1 
ATOM   3879 H  HD2  B LYS   A 1 224 ? 37.86507 -6.57140  36.74972  0.400 68.84632  ? 224 LYS   A HD2  1 
ATOM   3880 H  HD3  A LYS   A 1 224 ? 38.40076 -5.84404  36.18743  0.600 72.79545  ? 224 LYS   A HD3  1 
ATOM   3881 H  HD3  B LYS   A 1 224 ? 36.36507 -6.17961  37.09887  0.400 68.84632  ? 224 LYS   A HD3  1 
ATOM   3882 H  HE2  A LYS   A 1 224 ? 39.39723 -3.99484  35.36280  0.600 63.49024  ? 224 LYS   A HE2  1 
ATOM   3883 H  HE2  B LYS   A 1 224 ? 35.98816 -8.30783  35.71795  0.400 59.31093  ? 224 LYS   A HE2  1 
ATOM   3884 H  HE3  A LYS   A 1 224 ? 38.96756 -4.82390  34.07693  0.600 63.49024  ? 224 LYS   A HE3  1 
ATOM   3885 H  HE3  B LYS   A 1 224 ? 37.36057 -8.65928  36.43795  0.400 59.31093  ? 224 LYS   A HE3  1 
ATOM   3886 H  HZ1  A LYS   A 1 224 ? 38.41806 -2.63265  33.83471  0.600 91.81130  ? 224 LYS   A HZ1  1 
ATOM   3887 H  HZ1  B LYS   A 1 224 ? 35.55339 -9.33106  37.68673  0.400 47.50493  ? 224 LYS   A HZ1  1 
ATOM   3888 H  HZ2  A LYS   A 1 224 ? 37.19792 -3.41336  33.84321  0.600 91.81130  ? 224 LYS   A HZ2  1 
ATOM   3889 H  HZ2  B LYS   A 1 224 ? 36.33434 -8.36767  38.43527  0.400 47.50493  ? 224 LYS   A HZ2  1 
ATOM   3890 H  HZ3  A LYS   A 1 224 ? 37.58386 -2.65989  35.01865  0.600 91.81130  ? 224 LYS   A HZ3  1 
ATOM   3891 H  HZ3  B LYS   A 1 224 ? 35.09241 -7.96326  37.80888  0.400 47.50493  ? 224 LYS   A HZ3  1 
ATOM   3892 N  N    . ILE   A 1 225 ? 32.50559 -5.22168  33.50149  1.000 38.97239  ? 225 ILE   A N    1 
ATOM   3893 C  CA   . ILE   A 1 225 ? 31.18857 -4.59803  33.41912  1.000 37.28764  ? 225 ILE   A CA   1 
ATOM   3894 C  C    . ILE   A 1 225 ? 30.09268 -5.65185  33.54170  1.000 58.39527  ? 225 ILE   A C    1 
ATOM   3895 O  O    . ILE   A 1 225 ? 29.11831 -5.46625  34.27486  1.000 45.59006  ? 225 ILE   A O    1 
ATOM   3896 C  CB   . ILE   A 1 225 ? 31.05914 -3.79216  32.11272  1.000 42.75506  ? 225 ILE   A CB   1 
ATOM   3897 C  CG1  . ILE   A 1 225 ? 31.98858 -2.57642  32.16938  1.000 43.68445  ? 225 ILE   A CG1  1 
ATOM   3898 C  CG2  . ILE   A 1 225 ? 29.62349 -3.35785  31.86673  1.000 41.00422  ? 225 ILE   A CG2  1 
ATOM   3899 C  CD1  . ILE   A 1 225 ? 31.94676 -1.69836  30.93230  1.000 61.36689  ? 225 ILE   A CD1  1 
ATOM   3900 H  H    . ILE   A 1 225 ? 32.96568 -5.17204  32.77661  1.000 46.78113  ? 225 ILE   A H    1 
ATOM   3901 H  HA   . ILE   A 1 225 ? 31.09122 -3.98121  34.16138  1.000 44.75944  ? 225 ILE   A HA   1 
ATOM   3902 H  HB   . ILE   A 1 225 ? 31.32033 -4.36398  31.37400  1.000 51.32034  ? 225 ILE   A HB   1 
ATOM   3903 H  HG12 . ILE   A 1 225 ? 31.73435 -2.02749  32.92763  1.000 52.43561  ? 225 ILE   A HG12 1 
ATOM   3904 H  HG13 . ILE   A 1 225 ? 32.90060 -2.88877  32.27688  1.000 52.43561  ? 225 ILE   A HG13 1 
ATOM   3905 H  HG21 . ILE   A 1 225 ? 29.58593 -2.84137  31.04652  1.000 49.21934  ? 225 ILE   A HG21 1 
ATOM   3906 H  HG22 . ILE   A 1 225 ? 29.06426 -4.14639  31.78698  1.000 49.21934  ? 225 ILE   A HG22 1 
ATOM   3907 H  HG23 . ILE   A 1 225 ? 29.32542 -2.81507  32.61335  1.000 49.21934  ? 225 ILE   A HG23 1 
ATOM   3908 H  HD11 . ILE   A 1 225 ? 32.65822 -1.04131  30.98720  1.000 73.65454  ? 225 ILE   A HD11 1 
ATOM   3909 H  HD12 . ILE   A 1 225 ? 32.06933 -2.25375  30.14654  1.000 73.65454  ? 225 ILE   A HD12 1 
ATOM   3910 H  HD13 . ILE   A 1 225 ? 31.08663 -1.25187  30.89088  1.000 73.65454  ? 225 ILE   A HD13 1 
ATOM   3911 N  N    . VAL   A 1 226 ? 30.23094 -6.77446  32.82971  1.000 46.62684  ? 226 VAL   A N    1 
ATOM   3912 C  CA   . VAL   A 1 226 ? 29.16229 -7.77037  32.84351  1.000 46.56887  ? 226 VAL   A CA   1 
ATOM   3913 C  C    . VAL   A 1 226 ? 29.16867 -8.55260  34.15291  1.000 42.52513  ? 226 VAL   A C    1 
ATOM   3914 O  O    . VAL   A 1 226 ? 28.10878 -8.84420  34.71324  1.000 43.49089  ? 226 VAL   A O    1 
ATOM   3915 C  CB   . VAL   A 1 226 ? 29.27061 -8.71124  31.62379  1.000 41.68572  ? 226 VAL   A CB   1 
ATOM   3916 C  CG1  . VAL   A 1 226 ? 29.27784 -7.89943  30.33387  1.000 34.98608  ? 226 VAL   A CG1  1 
ATOM   3917 C  CG2  . VAL   A 1 226 ? 30.49619 -9.58820  31.72530  1.000 47.67487  ? 226 VAL   A CG2  1 
ATOM   3918 H  H    . VAL   A 1 226 ? 30.91307 -6.97546  32.34607  1.000 55.96647  ? 226 VAL   A H    1 
ATOM   3919 H  HA   . VAL   A 1 226 ? 28.31667 -7.29993  32.77641  1.000 55.89691  ? 226 VAL   A HA   1 
ATOM   3920 H  HB   . VAL   A 1 226 ? 28.49789 -9.29734  31.60708  1.000 50.03713  ? 226 VAL   A HB   1 
ATOM   3921 H  HG11 . VAL   A 1 226 ? 29.22441 -8.50592  29.57874  1.000 41.99757  ? 226 VAL   A HG11 1 
ATOM   3922 H  HG12 . VAL   A 1 226 ? 28.51395 -7.30162  30.33268  1.000 41.99757  ? 226 VAL   A HG12 1 
ATOM   3923 H  HG13 . VAL   A 1 226 ? 30.09964 -7.38614  30.28837  1.000 41.99757  ? 226 VAL   A HG13 1 
ATOM   3924 H  HG21 . VAL   A 1 226 ? 30.64360 -10.02490 30.87181  1.000 57.22411  ? 226 VAL   A HG21 1 
ATOM   3925 H  HG22 . VAL   A 1 226 ? 31.26142 -9.03654  31.95114  1.000 57.22411  ? 226 VAL   A HG22 1 
ATOM   3926 H  HG23 . VAL   A 1 226 ? 30.35227 -10.25321 32.41664  1.000 57.22411  ? 226 VAL   A HG23 1 
ATOM   3927 N  N    . ASP   A 1 227 ? 30.35217 -8.91134  34.65463  1.000 44.75724  ? 227 ASP   A N    1 
ATOM   3928 C  CA   . ASP   A 1 227 ? 30.42543 -9.60938  35.93493  1.000 53.73203  ? 227 ASP   A CA   1 
ATOM   3929 C  C    . ASP   A 1 227 ? 29.71855 -8.81773  37.02594  1.000 59.93259  ? 227 ASP   A C    1 
ATOM   3930 O  O    . ASP   A 1 227 ? 29.07936 -9.40064  37.91058  1.000 69.61523  ? 227 ASP   A O    1 
ATOM   3931 C  CB   . ASP   A 1 227 ? 31.87833 -9.86087  36.32980  1.000 46.92943  ? 227 ASP   A CB   1 
ATOM   3932 C  CG   . ASP   A 1 227 ? 32.45750 -11.11093 35.68754  1.000 56.99613  ? 227 ASP   A CG   1 
ATOM   3933 O  OD1  . ASP   A 1 227 ? 31.69449 -11.88920 35.06491  1.000 66.22036  ? 227 ASP   A OD1  1 
ATOM   3934 O  OD2  . ASP   A 1 227 ? 33.68314 -11.31776 35.80399  1.000 69.12246  ? 227 ASP   A OD2  1 
ATOM   3935 H  H    . ASP   A 1 227 ? 31.11233 -8.76479  34.28008  1.000 53.72296  ? 227 ASP   A H    1 
ATOM   3936 H  HA   . ASP   A 1 227 ? 29.98945 -10.47062 35.83962  1.000 64.49270  ? 227 ASP   A HA   1 
ATOM   3937 H  HB2  . ASP   A 1 227 ? 32.41682 -9.10389  36.05067  1.000 56.32959  ? 227 ASP   A HB2  1 
ATOM   3938 H  HB3  . ASP   A 1 227 ? 31.92980 -9.96759  37.29254  1.000 56.32959  ? 227 ASP   A HB3  1 
ATOM   3939 N  N    . GLU   A 1 228 ? 29.81391 -7.48817  36.97532  1.000 52.84564  ? 228 GLU   A N    1 
ATOM   3940 C  CA   . GLU   A 1 228 ? 29.20815 -6.65525  38.00661  1.000 59.72912  ? 228 GLU   A CA   1 
ATOM   3941 C  C    . GLU   A 1 228 ? 27.71379 -6.48442  37.78224  1.000 71.05440  ? 228 GLU   A C    1 
ATOM   3942 O  O    . GLU   A 1 228 ? 26.93923 -6.48835  38.74462  1.000 55.39084  ? 228 GLU   A O    1 
ATOM   3943 C  CB   . GLU   A 1 228 ? 29.90458 -5.29622  38.05524  1.000 50.55053  ? 228 GLU   A CB   1 
ATOM   3944 C  CG   . GLU   A 1 228 ? 31.33772 -5.37835  38.57441  1.000 103.32622 ? 228 GLU   A CG   1 
ATOM   3945 C  CD   . GLU   A 1 228 ? 32.03809 -4.03460  38.59027  1.000 106.35114 ? 228 GLU   A CD   1 
ATOM   3946 O  OE1  . GLU   A 1 228 ? 33.28798 -4.02227  38.58977  1.000 84.98389  ? 228 GLU   A OE1  1 
ATOM   3947 O  OE2  . GLU   A 1 228 ? 31.34169 -2.99474  38.60104  1.000 91.73431  ? 228 GLU   A OE2  1 
ATOM   3948 H  H    . GLU   A 1 228 ? 30.22130 -7.04911  36.35818  1.000 63.42904  ? 228 GLU   A H    1 
ATOM   3949 H  HA   . GLU   A 1 228 ? 29.33058 -7.08408  38.86802  1.000 71.68922  ? 228 GLU   A HA   1 
ATOM   3950 H  HB2  . GLU   A 1 228 ? 29.93146 -4.92420  37.15982  1.000 60.67491  ? 228 GLU   A HB2  1 
ATOM   3951 H  HB3  . GLU   A 1 228 ? 29.40619 -4.70813  38.64401  1.000 60.67491  ? 228 GLU   A HB3  1 
ATOM   3952 H  HG2  . GLU   A 1 228 ? 31.32524 -5.71993  39.48219  1.000 124.00574 ? 228 GLU   A HG2  1 
ATOM   3953 H  HG3  . GLU   A 1 228 ? 31.84663 -5.97421  38.00269  1.000 124.00574 ? 228 GLU   A HG3  1 
ATOM   3954 N  N    . LEU   A 1 229 ? 27.28686 -6.33599  36.52605  1.000 50.11175  ? 229 LEU   A N    1 
ATOM   3955 C  CA   . LEU   A 1 229 ? 25.85555 -6.32673  36.24186  1.000 44.51940  ? 229 LEU   A CA   1 
ATOM   3956 C  C    . LEU   A 1 229 ? 25.18300 -7.58815  36.77529  1.000 38.51797  ? 229 LEU   A C    1 
ATOM   3957 O  O    . LEU   A 1 229 ? 23.99007 -7.56901  37.10128  1.000 57.06839  ? 229 LEU   A O    1 
ATOM   3958 C  CB   . LEU   A 1 229 ? 25.61549 -6.19770  34.73841  1.000 48.91565  ? 229 LEU   A CB   1 
ATOM   3959 C  CG   . LEU   A 1 229 ? 25.92159 -4.85150  34.07661  1.000 49.97359  ? 229 LEU   A CG   1 
ATOM   3960 C  CD1  . LEU   A 1 229 ? 25.90234 -4.98977  32.55579  1.000 56.04975  ? 229 LEU   A CD1  1 
ATOM   3961 C  CD2  . LEU   A 1 229 ? 24.93112 -3.78236  34.51040  1.000 47.22444  ? 229 LEU   A CD2  1 
ATOM   3962 H  H    . LEU   A 1 229 ? 27.79424 -6.24120  35.83817  1.000 60.14837  ? 229 LEU   A H    1 
ATOM   3963 H  HA   . LEU   A 1 229 ? 25.45390 -5.55664  36.67377  1.000 53.43755  ? 229 LEU   A HA   1 
ATOM   3964 H  HB2  . LEU   A 1 229 ? 26.16831 -6.85917  34.29373  1.000 58.71306  ? 229 LEU   A HB2  1 
ATOM   3965 H  HB3  . LEU   A 1 229 ? 24.67796 -6.38323  34.57255  1.000 58.71306  ? 229 LEU   A HB3  1 
ATOM   3966 H  HG   . LEU   A 1 229 ? 26.80656 -4.56974  34.35650  1.000 59.98258  ? 229 LEU   A HG   1 
ATOM   3967 H  HD11 . LEU   A 1 229 ? 26.07952 -4.12319  32.15763  1.000 67.27397  ? 229 LEU   A HD11 1 
ATOM   3968 H  HD12 . LEU   A 1 229 ? 26.58633 -5.62311  32.28759  1.000 67.27397  ? 229 LEU   A HD12 1 
ATOM   3969 H  HD13 . LEU   A 1 229 ? 25.02921 -5.30880  32.27872  1.000 67.27397  ? 229 LEU   A HD13 1 
ATOM   3970 H  HD21 . LEU   A 1 229 ? 25.13378 -2.95628  34.04412  1.000 56.68360  ? 229 LEU   A HD21 1 
ATOM   3971 H  HD22 . LEU   A 1 229 ? 24.03324 -4.07531  34.28929  1.000 56.68360  ? 229 LEU   A HD22 1 
ATOM   3972 H  HD23 . LEU   A 1 229 ? 25.00925 -3.64939  35.46806  1.000 56.68360  ? 229 LEU   A HD23 1 
ATOM   3973 N  N    . ASN   A 1 230 ? 25.92731 -8.68918  36.86055  1.000 40.74070  ? 230 ASN   A N    1 
ATOM   3974 C  CA   . ASN   A 1 230 ? 25.42290 -9.94054  37.39648  1.000 42.12741  ? 230 ASN   A CA   1 
ATOM   3975 C  C    . ASN   A 1 230 ? 25.70673 -10.09404 38.89061  1.000 54.88691  ? 230 ASN   A C    1 
ATOM   3976 O  O    . ASN   A 1 230 ? 25.63309 -11.21491 39.41213  1.000 52.72932  ? 230 ASN   A O    1 
ATOM   3977 C  CB   . ASN   A 1 230 ? 26.02900 -11.12007 36.63878  1.000 40.12899  ? 230 ASN   A CB   1 
ATOM   3978 C  CG   . ASN   A 1 230 ? 25.45770 -11.26024 35.23759  1.000 38.70268  ? 230 ASN   A CG   1 
ATOM   3979 O  OD1  . ASN   A 1 230 ? 24.39293 -10.71918 34.93440  1.000 42.03650  ? 230 ASN   A OD1  1 
ATOM   3980 N  ND2  . ASN   A 1 230 ? 26.17311 -11.97343 34.37619  1.000 41.56177  ? 230 ASN   A ND2  1 
ATOM   3981 H  H    . ASN   A 1 230 ? 26.74782 -8.73217  36.60655  1.000 48.90311  ? 230 ASN   A H    1 
ATOM   3982 H  HA   . ASN   A 1 230 ? 24.46172 -9.95836  37.26718  1.000 50.56716  ? 230 ASN   A HA   1 
ATOM   3983 H  HB2  . ASN   A 1 230 ? 26.98724 -10.99026 36.56250  1.000 48.16906  ? 230 ASN   A HB2  1 
ATOM   3984 H  HB3  . ASN   A 1 230 ? 25.84275 -11.93906 37.12404  1.000 48.16906  ? 230 ASN   A HB3  1 
ATOM   3985 H  HD21 . ASN   A 1 230 ? 25.89257 -12.08221 33.57054  1.000 49.88840  ? 230 ASN   A HD21 1 
ATOM   3986 H  HD22 . ASN   A 1 230 ? 26.91709 -12.32667 34.62382  1.000 49.88840  ? 230 ASN   A HD22 1 
ATOM   3987 N  N    . GLY   A 1 231 ? 26.04208 -9.00263  39.57511  1.000 68.94244  ? 231 GLY   A N    1 
ATOM   3988 C  CA   . GLY   A 1 231 ? 26.33537 -9.04912  40.99832  1.000 75.11560  ? 231 GLY   A CA   1 
ATOM   3989 C  C    . GLY   A 1 231 ? 27.32697 -10.13316 41.37466  1.000 52.53073  ? 231 GLY   A C    1 
ATOM   3990 O  O    . GLY   A 1 231 ? 28.21294 -10.47858 40.58871  1.000 79.72157  ? 231 GLY   A O    1 
ATOM   3991 H  H    . GLY   A 1 231 ? 26.10641 -8.21683  39.23161  1.000 82.74520  ? 231 GLY   A H    1 
ATOM   3992 H  HA2  . GLY   A 1 231 ? 26.70347 -8.19504  41.27392  1.000 90.15299  ? 231 GLY   A HA2  1 
ATOM   3993 H  HA3  . GLY   A 1 231 ? 25.51267 -9.21062  41.48615  1.000 90.15299  ? 231 GLY   A HA3  1 
HETATM 3994 C  C1   A PEG   B 2 .   ? 35.44674 -4.01984  3.95713   1.000 72.28662  ? 301 PEG   A C1   1 
HETATM 3995 O  O1   A PEG   B 2 .   ? 34.56820 -4.64280  4.86079   1.000 75.83763  ? 301 PEG   A O1   1 
HETATM 3996 C  C2   A PEG   B 2 .   ? 36.83121 -3.87597  4.55632   1.000 61.76736  ? 301 PEG   A C2   1 
HETATM 3997 O  O2   A PEG   B 2 .   ? 37.45331 -5.13827  4.74778   1.000 81.85347  ? 301 PEG   A O2   1 
HETATM 3998 C  C3   A PEG   B 2 .   ? 37.87681 -5.72092  3.54842   1.000 65.12471  ? 301 PEG   A C3   1 
HETATM 3999 C  C4   A PEG   B 2 .   ? 38.70737 -6.95620  3.78157   1.000 60.72372  ? 301 PEG   A C4   1 
HETATM 4000 O  O4   A PEG   B 2 .   ? 37.92748 -8.12124  3.53019   1.000 68.34771  ? 301 PEG   A O4   1 
HETATM 4001 H  H11  A PEG   B 2 .   ? 35.51719 -4.53074  3.13560   1.000 86.75822  ? 301 PEG   A H11  1 
HETATM 4002 H  H12  A PEG   B 2 .   ? 35.12310 -3.13890  3.71198   1.000 86.75822  ? 301 PEG   A H12  1 
HETATM 4003 H  HO1  A PEG   B 2 .   ? 33.78556 -4.61133  4.53068   1.000 91.01943  ? 301 PEG   A HO1  1 
HETATM 4004 H  H21  A PEG   B 2 .   ? 36.74746 -3.39730  5.39582   1.000 74.13511  ? 301 PEG   A H21  1 
HETATM 4005 H  H22  A PEG   B 2 .   ? 37.35731 -3.31353  3.96660   1.000 74.13511  ? 301 PEG   A H22  1 
HETATM 4006 H  H31  A PEG   B 2 .   ? 37.10890 -5.95484  3.00392   1.000 78.16393  ? 301 PEG   A H31  1 
HETATM 4007 H  H32  A PEG   B 2 .   ? 38.39688 -5.08296  3.03516   1.000 78.16393  ? 301 PEG   A H32  1 
HETATM 4008 H  H41  A PEG   B 2 .   ? 39.03459 -6.91993  4.69399   1.000 72.88273  ? 301 PEG   A H41  1 
HETATM 4009 H  H42  A PEG   B 2 .   ? 39.48401 -6.89912  3.20323   1.000 72.88273  ? 301 PEG   A H42  1 
HETATM 4010 H  HO4  A PEG   B 2 .   ? 38.45840 -8.77761  3.43118   1.000 82.03152  ? 301 PEG   A HO4  1 
HETATM 4011 C  C10  A A1IGD C 3 .   ? 36.62145 -5.85536  -0.71954  0.350 52.88712  ? 302 A1IGD A C10  1 
HETATM 4012 C  C10  B A1IGD C 3 .   ? 36.20434 -5.97136  -1.13342  0.350 42.93285  ? 302 A1IGD A C10  1 
HETATM 4013 C  C02  A A1IGD C 3 .   ? 36.41284 -5.45875  -2.03160  0.350 36.95997  ? 302 A1IGD A C02  1 
HETATM 4014 C  C02  B A1IGD C 3 .   ? 35.94528 -5.90966  0.24046   0.350 43.19056  ? 302 A1IGD A C02  1 
HETATM 4015 C  C03  A A1IGD C 3 .   ? 36.97245 -4.27586  -2.49474  0.350 39.49058  ? 302 A1IGD A C03  1 
HETATM 4016 C  C03  B A1IGD C 3 .   ? 36.59662 -4.96655  1.02047   0.350 45.82835  ? 302 A1IGD A C03  1 
HETATM 4017 C  C04  A A1IGD C 3 .   ? 37.75428 -3.47206  -1.64144  0.350 36.71394  ? 302 A1IGD A C04  1 
HETATM 4018 C  C04  B A1IGD C 3 .   ? 37.52061 -4.07361  0.44262   0.350 35.82583  ? 302 A1IGD A C04  1 
HETATM 4019 C  C05  A A1IGD C 3 .   ? 37.96114 -3.87931  -0.32861  0.350 39.70090  ? 302 A1IGD A C05  1 
HETATM 4020 C  C05  B A1IGD C 3 .   ? 37.76949 -4.14317  -0.92986  0.350 34.06659  ? 302 A1IGD A C05  1 
HETATM 4021 C  C09  A A1IGD C 3 .   ? 37.39902 -5.06192  0.14478   0.350 43.73766  ? 302 A1IGD A C09  1 
HETATM 4022 C  C09  B A1IGD C 3 .   ? 37.12347 -5.07976  -1.72262  0.350 27.89153  ? 302 A1IGD A C09  1 
HETATM 4023 I  I01  A A1IGD C 3 .   ? 35.30820 -6.52739  -3.33834  0.350 45.86292  ? 302 A1IGD A I01  1 
HETATM 4024 I  I01  B A1IGD C 3 .   ? 34.62746 -7.13789  1.20487   0.350 38.24167  ? 302 A1IGD A I01  1 
HETATM 4025 N  N06  A A1IGD C 3 .   ? 38.78225 -3.03270  0.58682   0.350 39.69074  ? 302 A1IGD A N06  1 
HETATM 4026 N  N06  B A1IGD C 3 .   ? 38.73888 -3.19708  -1.53540  0.350 32.08780  ? 302 A1IGD A N06  1 
HETATM 4027 N  N11  A A1IGD C 3 .   ? 36.03174 -7.11601  -0.19711  0.350 52.71048  ? 302 A1IGD A N11  1 
HETATM 4028 N  N11  B A1IGD C 3 .   ? 35.53360 -6.96017  -1.98865  0.350 33.62265  ? 302 A1IGD A N11  1 
HETATM 4029 O  O07  A A1IGD C 3 .   ? 38.52360 -3.08626  1.80532   0.350 45.22368  ? 302 A1IGD A O07  1 
HETATM 4030 O  O07  B A1IGD C 3 .   ? 38.77957 -3.12762  -2.78143  0.350 37.89952  ? 302 A1IGD A O07  1 
HETATM 4031 O  O08  A A1IGD C 3 .   ? 39.65058 -2.32400  0.18541   0.350 33.47415  ? 302 A1IGD A O08  1 
HETATM 4032 O  O08  B A1IGD C 3 .   ? 39.44691 -2.52587  -0.86584  0.350 38.61448  ? 302 A1IGD A O08  1 
HETATM 4033 O  O12  A A1IGD C 3 .   ? 36.28453 -8.17539  -0.79158  0.350 61.23419  ? 302 A1IGD A O12  1 
HETATM 4034 O  O12  B A1IGD C 3 .   ? 35.55067 -8.14862  -1.62990  0.350 46.84996  ? 302 A1IGD A O12  1 
HETATM 4035 O  O13  A A1IGD C 3 .   ? 35.32953 -7.14289  0.77215   0.350 55.28144  ? 302 A1IGD A O13  1 
HETATM 4036 O  O13  B A1IGD C 3 .   ? 34.98662 -6.66509  -3.01560  0.350 54.55332  ? 302 A1IGD A O13  1 
HETATM 4037 H  H031 A A1IGD C 3 .   ? 36.81933 -3.94391  -3.52692  0.350 47.40297  ? 302 A1IGD A H031 1 
HETATM 4038 H  H031 B A1IGD C 3 .   ? 36.40798 -4.89567  2.09677   0.350 55.00829  ? 302 A1IGD A H031 1 
HETATM 4039 H  H041 A A1IGD C 3 .   ? 38.19413 -2.53316  -2.01479  0.350 44.07100  ? 302 A1IGD A H041 1 
HETATM 4040 H  H041 B A1IGD C 3 .   ? 38.03849 -3.33063  1.07046   0.350 43.00527  ? 302 A1IGD A H041 1 
HETATM 4041 H  H091 A A1IGD C 3 .   ? 37.56451 -5.36949  1.18786   0.350 52.49946  ? 302 A1IGD A H091 1 
HETATM 4042 H  H091 B A1IGD C 3 .   ? 37.33021 -5.12240  -2.80218  0.350 33.48411  ? 302 A1IGD A H091 1 
HETATM 4043 CL CL   A CL    D 4 .   ? 32.16993 -8.30913  2.41104   0.800 43.62136  ? 303 CL    A CL   1 
HETATM 4044 O  O    . HOH   E 5 .   ? 29.54420 5.43132   -3.87162  1.000 63.27835  ? 401 HOH   A O    1 
HETATM 4045 O  O    . HOH   E 5 .   ? 37.11591 -19.87203 27.17831  1.000 51.68589  ? 402 HOH   A O    1 
HETATM 4046 O  O    . HOH   E 5 .   ? 37.51477 -13.42208 -7.42883  1.000 45.59011  ? 403 HOH   A O    1 
HETATM 4047 O  O    . HOH   E 5 .   ? 35.28969 -15.20324 -3.73819  1.000 51.79786  ? 404 HOH   A O    1 
HETATM 4048 O  O    . HOH   E 5 .   ? 30.59693 -7.04580  -9.18301  1.000 50.09925  ? 405 HOH   A O    1 
HETATM 4049 O  O    . HOH   E 5 .   ? 36.92667 13.10612  -3.65506  1.000 54.42137  ? 406 HOH   A O    1 
HETATM 4050 O  O    A HOH   E 5 .   ? 42.18547 -5.95299  -14.84966 0.500 46.45387  ? 407 HOH   A O    1 
HETATM 4051 O  O    . HOH   E 5 .   ? 49.68877 5.67365   3.68435   1.000 43.15786  ? 408 HOH   A O    1 
HETATM 4052 O  O    . HOH   E 5 .   ? 42.940   -10.593   -9.773    1.000 53.57033  ? 409 HOH   A O    1 
HETATM 4053 O  O    . HOH   E 5 .   ? 20.77449 -5.34251  28.62500  1.000 42.86213  ? 410 HOH   A O    1 
HETATM 4054 O  O    . HOH   E 5 .   ? 37.26476 13.45210  18.46722  1.000 58.17141  ? 411 HOH   A O    1 
HETATM 4055 O  O    . HOH   E 5 .   ? 41.42834 13.61477  1.08518   1.000 59.35111  ? 412 HOH   A O    1 
HETATM 4056 O  O    A HOH   E 5 .   ? 39.16336 9.29311   2.39402   0.500 34.01260  ? 413 HOH   A O    1 
HETATM 4057 O  O    B HOH   E 5 .   ? 44.252   4.899     -18.965   0.500 31.31423  ? 414 HOH   A O    1 
HETATM 4058 O  O    . HOH   E 5 .   ? 28.36554 -14.88405 1.61267   1.000 34.37700  ? 415 HOH   A O    1 
HETATM 4059 O  O    B HOH   E 5 .   ? 33.34848 -5.29195  19.10410  0.500 30.52133  ? 416 HOH   A O    1 
HETATM 4060 O  O    . HOH   E 5 .   ? 34.17200 11.62545  17.16882  1.000 53.84670  ? 417 HOH   A O    1 
HETATM 4061 O  O    . HOH   E 5 .   ? 25.57338 -16.59380 31.28659  1.000 47.92616  ? 418 HOH   A O    1 
HETATM 4062 O  O    . HOH   E 5 .   ? 51.69824 2.31950   -1.15087  1.000 53.97135  ? 419 HOH   A O    1 
HETATM 4063 O  O    . HOH   E 5 .   ? 30.38212 -21.81433 24.82015  1.000 48.03138  ? 420 HOH   A O    1 
HETATM 4064 O  O    . HOH   E 5 .   ? 16.96206 -19.15239 28.77754  1.000 44.77632  ? 421 HOH   A O    1 
HETATM 4065 O  O    . HOH   E 5 .   ? 46.00037 -10.76824 26.07296  1.000 52.98659  ? 422 HOH   A O    1 
HETATM 4066 O  O    . HOH   E 5 .   ? 38.76470 -7.74797  -17.74814 1.000 49.68752  ? 423 HOH   A O    1 
HETATM 4067 O  O    . HOH   E 5 .   ? 33.73714 -18.87448 4.50686   1.000 39.69256  ? 424 HOH   A O    1 
HETATM 4068 O  O    . HOH   E 5 .   ? 38.84657 -5.71802  -16.22688 1.000 42.33844  ? 425 HOH   A O    1 
HETATM 4069 O  O    . HOH   E 5 .   ? 15.82111 -8.67842  2.66303   1.000 46.75855  ? 426 HOH   A O    1 
HETATM 4070 O  O    . HOH   E 5 .   ? 36.82923 -1.31358  2.69349   1.000 58.84793  ? 427 HOH   A O    1 
HETATM 4071 O  O    . HOH   E 5 .   ? 45.20566 6.68515   2.39924   1.000 41.71111  ? 428 HOH   A O    1 
HETATM 4072 O  O    . HOH   E 5 .   ? 42.00032 12.40364  -6.83511  1.000 31.35190  ? 429 HOH   A O    1 
HETATM 4073 O  O    . HOH   E 5 .   ? 17.546   -19.755   26.019    1.000 39.12572  ? 430 HOH   A O    1 
HETATM 4074 O  O    . HOH   E 5 .   ? 32.61488 -22.41477 19.24480  1.000 67.61186  ? 431 HOH   A O    1 
HETATM 4075 O  O    . HOH   E 5 .   ? 51.50505 -1.17361  -6.71011  1.000 41.97644  ? 432 HOH   A O    1 
HETATM 4076 O  O    . HOH   E 5 .   ? 27.15313 -17.15452 10.37689  1.000 33.69843  ? 433 HOH   A O    1 
HETATM 4077 O  O    . HOH   E 5 .   ? 44.40129 -2.63250  -12.80108 1.000 44.84702  ? 434 HOH   A O    1 
HETATM 4078 O  O    . HOH   E 5 .   ? 30.90440 -5.47568  10.77902  1.000 45.40063  ? 435 HOH   A O    1 
HETATM 4079 O  O    . HOH   E 5 .   ? 25.79795 -13.57022 16.69180  1.000 29.62457  ? 436 HOH   A O    1 
HETATM 4080 O  O    . HOH   E 5 .   ? 29.24356 2.99854   -6.47750  1.000 65.62480  ? 437 HOH   A O    1 
HETATM 4081 O  O    . HOH   E 5 .   ? 51.11224 2.82957   -7.73902  1.000 42.61856  ? 438 HOH   A O    1 
HETATM 4082 O  O    . HOH   E 5 .   ? 39.42334 -20.29999 17.32912  1.000 42.61364  ? 439 HOH   A O    1 
HETATM 4083 O  O    . HOH   E 5 .   ? 31.83696 -20.05093 15.73644  1.000 37.46037  ? 440 HOH   A O    1 
HETATM 4084 O  O    . HOH   E 5 .   ? 36.94999 -14.87959 -12.19760 1.000 40.04194  ? 441 HOH   A O    1 
HETATM 4085 O  O    . HOH   E 5 .   ? 41.43628 2.12498   6.62869   1.000 58.69949  ? 442 HOH   A O    1 
HETATM 4086 O  O    . HOH   E 5 .   ? 26.86558 -22.45266 19.20743  1.000 48.51881  ? 443 HOH   A O    1 
HETATM 4087 O  O    . HOH   E 5 .   ? 49.22081 0.10634   8.72057   1.000 46.80224  ? 444 HOH   A O    1 
HETATM 4088 O  O    . HOH   E 5 .   ? 46.70351 3.27539   17.03148  1.000 77.77254  ? 445 HOH   A O    1 
HETATM 4089 O  O    . HOH   E 5 .   ? 39.699   12.933    -10.843   1.000 46.03978  ? 446 HOH   A O    1 
HETATM 4090 O  O    . HOH   E 5 .   ? 39.16411 5.91725   -17.55944 1.000 46.42439  ? 447 HOH   A O    1 
HETATM 4091 O  O    . HOH   E 5 .   ? 20.062   -11.434   2.646     1.000 36.23808  ? 448 HOH   A O    1 
HETATM 4092 O  O    . HOH   E 5 .   ? 34.10112 7.49438   -12.11609 1.000 47.62650  ? 449 HOH   A O    1 
HETATM 4093 O  O    . HOH   E 5 .   ? 22.64989 -18.41207 25.65036  1.000 40.15432  ? 450 HOH   A O    1 
HETATM 4094 O  O    . HOH   E 5 .   ? 36.65960 0.43667   13.43665  1.000 59.86913  ? 451 HOH   A O    1 
HETATM 4095 O  O    . HOH   E 5 .   ? 19.60239 -5.73618  10.28381  1.000 36.17703  ? 452 HOH   A O    1 
HETATM 4096 O  O    . HOH   E 5 .   ? 41.171   11.550    -12.670   1.000 39.62154  ? 453 HOH   A O    1 
HETATM 4097 O  O    . HOH   E 5 .   ? 15.40820 -13.51360 21.35584  1.000 40.66144  ? 454 HOH   A O    1 
HETATM 4098 O  O    . HOH   E 5 .   ? 44.080   -15.540   17.187    1.000 46.74254  ? 455 HOH   A O    1 
HETATM 4099 O  O    . HOH   E 5 .   ? 35.46250 -6.99476  -15.76390 1.000 73.24058  ? 456 HOH   A O    1 
HETATM 4100 O  O    . HOH   E 5 .   ? 44.78414 -11.80460 23.80309  1.000 42.50475  ? 457 HOH   A O    1 
HETATM 4101 O  O    . HOH   E 5 .   ? 45.64966 -12.40458 9.72894   1.000 52.46595  ? 458 HOH   A O    1 
HETATM 4102 O  O    . HOH   E 5 .   ? 39.79511 -10.68476 -19.58250 1.000 50.07025  ? 459 HOH   A O    1 
HETATM 4103 O  O    . HOH   E 5 .   ? 14.88231 -17.07027 26.58599  1.000 44.08573  ? 460 HOH   A O    1 
HETATM 4104 O  O    . HOH   E 5 .   ? 39.79480 2.61927   -16.78762 1.000 42.82207  ? 461 HOH   A O    1 
HETATM 4105 O  O    . HOH   E 5 .   ? 29.50541 -18.02707 9.52996   1.000 32.50118  ? 462 HOH   A O    1 
HETATM 4106 O  O    . HOH   E 5 .   ? 31.38201 12.90156  26.55085  1.000 49.37257  ? 463 HOH   A O    1 
HETATM 4107 O  O    . HOH   E 5 .   ? 15.21548 -11.77867 18.90331  1.000 34.69220  ? 464 HOH   A O    1 
HETATM 4108 O  O    . HOH   E 5 .   ? 24.70749 -16.04447 4.72336   1.000 33.30888  ? 465 HOH   A O    1 
HETATM 4109 O  O    . HOH   E 5 .   ? 51.20868 8.75154   0.34320   1.000 47.48939  ? 466 HOH   A O    1 
HETATM 4110 O  O    . HOH   E 5 .   ? 41.22036 -15.68114 28.88052  1.000 43.18970  ? 467 HOH   A O    1 
HETATM 4111 O  O    . HOH   E 5 .   ? 28.29425 0.87645   -5.24001  1.000 45.05501  ? 468 HOH   A O    1 
HETATM 4112 O  O    . HOH   E 5 .   ? 28.73328 -22.88555 21.16517  1.000 45.61653  ? 469 HOH   A O    1 
HETATM 4113 O  O    . HOH   E 5 .   ? 14.19340 -1.50426  4.73127   1.000 50.07691  ? 470 HOH   A O    1 
HETATM 4114 O  O    . HOH   E 5 .   ? 45.29808 -13.51950 14.26030  1.000 49.11772  ? 471 HOH   A O    1 
HETATM 4115 O  O    . HOH   E 5 .   ? 47.48440 10.76690  -0.52022  1.000 46.41852  ? 472 HOH   A O    1 
HETATM 4116 O  O    . HOH   E 5 .   ? 15.92391 -17.31621 28.75442  1.000 49.19647  ? 473 HOH   A O    1 
HETATM 4117 O  O    . HOH   E 5 .   ? 49.74525 -5.82043  -9.15118  1.000 43.90808  ? 474 HOH   A O    1 
HETATM 4118 O  O    . HOH   E 5 .   ? 29.22601 -5.10885  -8.73255  1.000 44.30338  ? 475 HOH   A O    1 
HETATM 4119 O  O    . HOH   E 5 .   ? 42.66318 12.62277  -2.38880  1.000 40.81698  ? 476 HOH   A O    1 
HETATM 4120 O  O    . HOH   E 5 .   ? 28.42721 4.51116   5.29736   1.000 58.87660  ? 477 HOH   A O    1 
HETATM 4121 O  O    . HOH   E 5 .   ? 40.47811 -18.51790 5.80098   1.000 46.12731  ? 478 HOH   A O    1 
HETATM 4122 O  O    . HOH   E 5 .   ? 37.76339 -2.97487  10.85878  1.000 44.68756  ? 479 HOH   A O    1 
HETATM 4123 O  O    A HOH   E 5 .   ? 45.87477 -0.18595  16.95398  0.500 38.11276  ? 480 HOH   A O    1 
HETATM 4124 O  O    . HOH   E 5 .   ? 28.57171 -1.96503  -12.10596 1.000 69.57600  ? 481 HOH   A O    1 
HETATM 4125 O  O    . HOH   E 5 .   ? 28.11077 12.45036  24.55766  1.000 50.55323  ? 482 HOH   A O    1 
HETATM 4126 O  O    . HOH   E 5 .   ? 38.17761 -0.22269  17.64527  1.000 59.21454  ? 483 HOH   A O    1 
HETATM 4127 O  O    . HOH   E 5 .   ? 38.396   -25.400   16.713    1.000 55.53569  ? 484 HOH   A O    1 
HETATM 4128 O  O    . HOH   E 5 .   ? 54.50721 -7.33791  3.05365   1.000 64.53411  ? 485 HOH   A O    1 
HETATM 4129 O  O    . HOH   E 5 .   ? 35.26715 0.01629   33.06921  1.000 58.84268  ? 486 HOH   A O    1 
HETATM 4130 O  O    . HOH   E 5 .   ? 36.11322 -11.10791 -0.58152  1.000 41.34732  ? 487 HOH   A O    1 
HETATM 4131 O  O    . HOH   E 5 .   ? 34.77893 -15.74186 0.13681   1.000 45.30407  ? 488 HOH   A O    1 
HETATM 4132 O  O    . HOH   E 5 .   ? 36.78240 -7.92776  -9.83790  1.000 35.04948  ? 489 HOH   A O    1 
HETATM 4133 O  O    . HOH   E 5 .   ? 44.00829 -11.02792 20.40738  1.000 43.15447  ? 490 HOH   A O    1 
HETATM 4134 O  O    . HOH   E 5 .   ? 45.80993 -0.49049  -15.48422 1.000 46.10592  ? 491 HOH   A O    1 
HETATM 4135 O  O    . HOH   E 5 .   ? 28.25509 -11.53200 -4.99232  1.000 43.57397  ? 492 HOH   A O    1 
HETATM 4136 O  O    . HOH   E 5 .   ? 42.89374 -7.91399  -13.44082 1.000 48.05360  ? 493 HOH   A O    1 
HETATM 4137 O  O    . HOH   E 5 .   ? 39.39090 8.17408   4.15625   1.000 51.92931  ? 494 HOH   A O    1 
HETATM 4138 O  O    . HOH   E 5 .   ? 26.86379 -19.06475 14.28832  1.000 38.48977  ? 495 HOH   A O    1 
HETATM 4139 O  O    . HOH   E 5 .   ? 33.16230 -2.09887  9.35369   1.000 67.81563  ? 496 HOH   A O    1 
HETATM 4140 O  O    . HOH   E 5 .   ? 45.288   -18.386   12.421    1.000 55.84880  ? 497 HOH   A O    1 
HETATM 4141 O  O    . HOH   E 5 .   ? 41.01151 1.28368   30.84152  1.000 63.82996  ? 498 HOH   A O    1 
HETATM 4142 O  O    . HOH   E 5 .   ? 14.69273 -8.58269  22.54509  1.000 46.07801  ? 499 HOH   A O    1 
HETATM 4143 O  O    . HOH   E 5 .   ? 31.93234 10.05169  1.74996   1.000 47.32487  ? 500 HOH   A O    1 
HETATM 4144 O  O    . HOH   E 5 .   ? 46.26405 -14.89810 2.04998   1.000 48.39050  ? 501 HOH   A O    1 
HETATM 4145 O  O    . HOH   E 5 .   ? 26.38926 -0.96318  15.61658  1.000 57.64351  ? 502 HOH   A O    1 
HETATM 4146 O  O    . HOH   E 5 .   ? 29.14429 -16.06319 -1.00009  1.000 46.19567  ? 503 HOH   A O    1 
HETATM 4147 O  O    . HOH   E 5 .   ? 37.95009 3.08829   19.37357  1.000 48.92424  ? 504 HOH   A O    1 
HETATM 4148 O  O    . HOH   E 5 .   ? 39.12868 -13.53519 -14.05370 1.000 35.14754  ? 505 HOH   A O    1 
HETATM 4149 O  O    . HOH   E 5 .   ? 35.08421 -13.39780 -1.33544  1.000 40.97237  ? 506 HOH   A O    1 
HETATM 4150 O  O    . HOH   E 5 .   ? 38.73220 -1.41122  -17.25610 1.000 41.08940  ? 507 HOH   A O    1 
HETATM 4151 O  O    . HOH   E 5 .   ? 39.11150 5.69819   19.54493  1.000 50.94948  ? 508 HOH   A O    1 
HETATM 4152 O  O    . HOH   E 5 .   ? 23.84825 -7.01549  -6.34389  1.000 42.82635  ? 509 HOH   A O    1 
HETATM 4153 O  O    . HOH   E 5 .   ? 37.12592 3.11408   16.17279  1.000 68.48444  ? 510 HOH   A O    1 
HETATM 4154 O  O    . HOH   E 5 .   ? 15.06610 0.40541   8.09490   1.000 54.70828  ? 511 HOH   A O    1 
HETATM 4155 O  O    . HOH   E 5 .   ? 32.02047 -14.57189 -4.97849  1.000 42.41280  ? 512 HOH   A O    1 
HETATM 4156 O  O    . HOH   E 5 .   ? 23.860   -17.873   28.083    1.000 40.27177  ? 513 HOH   A O    1 
HETATM 4157 O  O    B HOH   E 5 .   ? 36.31731 12.93912  21.95925  0.500 41.63039  ? 514 HOH   A O    1 
HETATM 4158 O  O    . HOH   E 5 .   ? 18.41959 -2.59286  -1.17208  1.000 52.31248  ? 515 HOH   A O    1 
HETATM 4159 O  O    . HOH   E 5 .   ? 17.92267 -8.86699  33.02415  1.000 68.63061  ? 516 HOH   A O    1 
HETATM 4160 O  O    . HOH   E 5 .   ? 14.423   -11.140   4.398     1.000 65.09008  ? 517 HOH   A O    1 
HETATM 4161 O  O    . HOH   E 5 .   ? 17.82412 -8.87142  0.33900   1.000 56.98013  ? 518 HOH   A O    1 
HETATM 4162 O  O    . HOH   E 5 .   ? 36.40435 -10.72978 -12.06398 1.000 49.89560  ? 519 HOH   A O    1 
HETATM 4163 O  O    . HOH   E 5 .   ? 12.40509 -11.18327 15.36378  1.000 54.43977  ? 520 HOH   A O    1 
HETATM 4164 O  O    . HOH   E 5 .   ? 27.17334 -12.40386 -0.74725  1.000 38.16345  ? 521 HOH   A O    1 
HETATM 4165 O  O    . HOH   E 5 .   ? 25.37875 12.58509  19.92372  1.000 57.02678  ? 522 HOH   A O    1 
HETATM 4166 O  O    . HOH   E 5 .   ? 36.31031 -3.05358  -17.15493 1.000 71.28342  ? 523 HOH   A O    1 
HETATM 4167 O  O    . HOH   E 5 .   ? 30.09519 1.28567   -11.03508 1.000 54.92026  ? 524 HOH   A O    1 
HETATM 4168 O  O    . HOH   E 5 .   ? 46.64072 -1.32196  -13.07389 1.000 52.62286  ? 525 HOH   A O    1 
HETATM 4169 O  O    . HOH   E 5 .   ? 11.26760 -18.41657 17.85028  1.000 55.82136  ? 526 HOH   A O    1 
HETATM 4170 O  O    . HOH   E 5 .   ? 50.18472 -5.58586  -2.09763  1.000 46.13061  ? 527 HOH   A O    1 
HETATM 4171 O  O    . HOH   E 5 .   ? 11.28257 -4.43951  7.53663   1.000 51.79030  ? 528 HOH   A O    1 
HETATM 4172 O  O    . HOH   E 5 .   ? 15.19730 -14.25299 27.63164  1.000 42.74777  ? 529 HOH   A O    1 
HETATM 4173 O  O    . HOH   E 5 .   ? 23.47668 -16.34811 0.42648   1.000 49.47904  ? 530 HOH   A O    1 
HETATM 4174 O  O    . HOH   E 5 .   ? 24.56494 -6.82011  41.14942  1.000 61.84809  ? 531 HOH   A O    1 
HETATM 4175 O  O    . HOH   E 5 .   ? 35.73130 0.63843   -15.01682 1.000 58.94382  ? 532 HOH   A O    1 
HETATM 4176 O  O    . HOH   E 5 .   ? 51.13710 -7.73780  -0.65037  1.000 52.06580  ? 533 HOH   A O    1 
HETATM 4177 O  O    . HOH   E 5 .   ? 46.02929 -11.15837 15.03338  1.000 46.42833  ? 534 HOH   A O    1 
HETATM 4178 O  O    . HOH   E 5 .   ? 49.15895 -11.25983 10.11375  1.000 66.13144  ? 535 HOH   A O    1 
HETATM 4179 O  O    . HOH   E 5 .   ? 12.33223 -6.52056  12.12771  1.000 57.94851  ? 536 HOH   A O    1 
HETATM 4180 O  O    . HOH   E 5 .   ? 31.57548 3.78661   31.46249  1.000 57.36160  ? 537 HOH   A O    1 
HETATM 4181 O  O    . HOH   E 5 .   ? 13.31755 -15.06707 21.95645  0.500 36.63710  ? 538 HOH   A O    1 
HETATM 4182 O  O    A HOH   E 5 .   ? 34.03107 -7.03157  38.09921  0.500 57.00831  ? 539 HOH   A O    1 
HETATM 4183 O  O    . HOH   E 5 .   ? 39.76108 13.41050  -6.00271  1.000 40.25395  ? 540 HOH   A O    1 
HETATM 4184 O  O    . HOH   E 5 .   ? 38.734   14.850    -7.676    1.000 42.23380  ? 541 HOH   A O    1 
HETATM 4185 O  O    . HOH   E 5 .   ? 46.21536 -13.98144 11.62563  1.000 47.01223  ? 542 HOH   A O    1 
HETATM 4186 O  O    . HOH   E 5 .   ? 26.31338 3.61313   6.16285   1.000 60.57912  ? 543 HOH   A O    1 
HETATM 4187 O  O    . HOH   E 5 .   ? 50.67269 10.92275  0.18584   1.000 70.79625  ? 544 HOH   A O    1 
HETATM 4188 O  O    . HOH   E 5 .   ? 26.94536 -1.01655  5.58825   1.000 60.50592  ? 545 HOH   A O    1 
HETATM 4189 O  O    . HOH   E 5 .   ? 35.84608 0.90060   4.12510   1.000 59.89884  ? 546 HOH   A O    1 
HETATM 4190 O  O    . HOH   E 5 .   ? 52.44168 1.51729   -15.74058 1.000 57.61839  ? 547 HOH   A O    1 
HETATM 4191 O  O    . HOH   E 5 .   ? 38.98611 -20.77406 14.51321  1.000 46.10909  ? 548 HOH   A O    1 
HETATM 4192 O  O    . HOH   E 5 .   ? 25.12580 -20.36310 16.28012  1.000 54.61271  ? 549 HOH   A O    1 
HETATM 4193 O  O    . HOH   E 5 .   ? 36.99191 -23.89456 10.19722  1.000 60.12093  ? 550 HOH   A O    1 
HETATM 4194 O  O    . HOH   E 5 .   ? 41.39956 1.32842   8.59786   1.000 56.59771  ? 551 HOH   A O    1 
HETATM 4195 O  O    . HOH   E 5 .   ? 36.41617 -1.21788  9.38023   1.000 63.18265  ? 552 HOH   A O    1 
HETATM 4196 O  O    . HOH   E 5 .   ? 26.599   -22.364   16.356    1.000 61.57663  ? 553 HOH   A O    1 
HETATM 4197 O  O    . HOH   E 5 .   ? 37.41020 -16.56311 32.94618  1.000 56.79685  ? 554 HOH   A O    1 
HETATM 4198 O  O    . HOH   E 5 .   ? 51.48606 -4.96466  -7.41584  1.000 41.17708  ? 555 HOH   A O    1 
HETATM 4199 O  O    . HOH   E 5 .   ? 41.537   14.867    -2.110    1.000 49.30784  ? 556 HOH   A O    1 
HETATM 4200 O  O    . HOH   E 5 .   ? 51.91748 -7.06398  8.69622   1.000 52.77681  ? 557 HOH   A O    1 
HETATM 4201 O  O    . HOH   E 5 .   ? 20.01599 2.78081   -2.60352  1.000 62.75682  ? 558 HOH   A O    1 
HETATM 4202 O  O    . HOH   E 5 .   ? 24.85498 0.60376   6.18462   1.000 57.65985  ? 559 HOH   A O    1 
HETATM 4203 O  O    . HOH   E 5 .   ? 33.13375 -24.21496 17.21560  1.000 55.67402  ? 560 HOH   A O    1 
HETATM 4204 O  O    . HOH   E 5 .   ? 11.19484 -5.11903  20.89505  1.000 64.27903  ? 561 HOH   A O    1 
HETATM 4205 O  O    . HOH   E 5 .   ? 40.080   -18.133   29.635    1.000 57.25293  ? 562 HOH   A O    1 
HETATM 4206 O  O    . HOH   E 5 .   ? 28.08075 1.02087   20.69248  1.000 56.00018  ? 563 HOH   A O    1 
HETATM 4207 O  O    . HOH   E 5 .   ? 46.46101 -1.60364  20.95247  1.000 57.44148  ? 564 HOH   A O    1 
HETATM 4208 O  O    . HOH   E 5 .   ? 13.37986 -3.30611  27.22303  1.000 69.01205  ? 565 HOH   A O    1 
HETATM 4209 O  O    . HOH   E 5 .   ? 29.06187 -0.84122  6.55926   1.000 61.17474  ? 566 HOH   A O    1 
HETATM 4210 O  O    . HOH   E 5 .   ? 39.384   15.233    -3.870    1.000 43.04770  ? 567 HOH   A O    1 
HETATM 4211 O  O    . HOH   E 5 .   ? 33.02762 1.69689   32.63088  1.000 60.75733  ? 568 HOH   A O    1 
HETATM 4212 O  O    . HOH   E 5 .   ? 50.46994 0.44800   -15.88757 1.000 57.04390  ? 569 HOH   A O    1 
HETATM 4213 O  O    . HOH   E 5 .   ? 14.13425 -16.91062 22.10986  1.000 57.13652  ? 570 HOH   A O    1 
HETATM 4214 O  O    . HOH   E 5 .   ? 45.92213 -14.17309 23.93632  1.000 53.45768  ? 571 HOH   A O    1 
HETATM 4215 O  O    . HOH   E 5 .   ? 34.41099 -22.39826 26.70816  1.000 61.36724  ? 572 HOH   A O    1 
HETATM 4216 O  O    . HOH   E 5 .   ? 37.68899 1.54492   -16.67175 1.000 57.60831  ? 573 HOH   A O    1 
HETATM 4217 O  O    B HOH   E 5 .   ? 35.63419 9.85974   -6.85959  0.400 36.22384  ? 574 HOH   A O    1 
HETATM 4218 O  O    . HOH   E 5 .   ? 51.62322 0.79535   -5.69465  1.000 59.14961  ? 575 HOH   A O    1 
HETATM 4219 O  O    . HOH   E 5 .   ? 26.84281 -12.89125 -3.46999  1.000 38.02482  ? 576 HOH   A O    1 
HETATM 4220 O  O    . HOH   E 5 .   ? 29.12653 -20.09570 14.12996  1.000 59.03539  ? 577 HOH   A O    1 
HETATM 4221 O  O    . HOH   E 5 .   ? 36.04345 -8.30389  -14.27522 1.000 58.04070  ? 578 HOH   A O    1 
HETATM 4222 O  O    . HOH   E 5 .   ? 11.63985 -4.04454  11.98196  1.000 52.20370  ? 579 HOH   A O    1 
HETATM 4223 O  O    B HOH   E 5 .   ? 38.79855 -0.91250  34.39509  0.500 50.47590  ? 580 HOH   A O    1 
HETATM 4224 O  O    . HOH   E 5 .   ? 53.96353 -7.74920  14.34997  1.000 73.24865  ? 581 HOH   A O    1 
HETATM 4225 O  O    . HOH   E 5 .   ? 47.83314 7.13941   7.46246   1.000 58.40428  ? 582 HOH   A O    1 
HETATM 4226 O  O    . HOH   E 5 .   ? 46.82809 -2.29401  18.55023  1.000 50.64623  ? 583 HOH   A O    1 
HETATM 4227 O  O    . HOH   E 5 .   ? 20.07391 8.29632   1.93858   1.000 66.11001  ? 584 HOH   A O    1 
HETATM 4228 O  O    . HOH   E 5 .   ? 36.59906 -12.41817 -14.19758 1.000 52.80087  ? 585 HOH   A O    1 
HETATM 4229 O  O    . HOH   E 5 .   ? 50.39790 0.16754   6.17077   1.000 47.26205  ? 586 HOH   A O    1 
HETATM 4230 O  O    . HOH   E 5 .   ? 13.02015 -11.54345 17.93585  1.000 59.04985  ? 587 HOH   A O    1 
HETATM 4231 O  O    . HOH   E 5 .   ? 31.16580 -19.74216 4.90221   1.000 55.71612  ? 588 HOH   A O    1 
HETATM 4232 O  O    A HOH   E 5 .   ? 34.45587 -1.31877  -15.78801 0.500 40.23167  ? 589 HOH   A O    1 
HETATM 4233 O  O    . HOH   E 5 .   ? 17.54404 -0.98535  29.73224  1.000 64.03295  ? 590 HOH   A O    1 
HETATM 4234 O  O    . HOH   E 5 .   ? 56.134   1.430     -15.545   1.000 68.97537  ? 591 HOH   A O    1 
HETATM 4235 O  O    B HOH   E 5 .   ? 39.05649 -4.08557  -18.73971 0.500 41.09511  ? 592 HOH   A O    1 
HETATM 4236 O  O    . HOH   E 5 .   ? 51.58252 4.87858   1.44510   1.000 55.51722  ? 593 HOH   A O    1 
HETATM 4237 O  O    . HOH   E 5 .   ? 37.870   15.975    -11.460   1.000 44.00585  ? 594 HOH   A O    1 
HETATM 4238 O  O    . HOH   E 5 .   ? 16.53750 6.13405   5.82109   1.000 74.55564  ? 595 HOH   A O    1 
HETATM 4239 O  O    . HOH   E 5 .   ? 13.80488 -1.03467  -0.35775  1.000 63.82796  ? 596 HOH   A O    1 
HETATM 4240 O  O    . HOH   E 5 .   ? 13.21475 -7.45934  2.03117   1.000 50.07320  ? 597 HOH   A O    1 
HETATM 4241 O  O    . HOH   E 5 .   ? 15.28419 -3.92520  -2.37188  1.000 52.85050  ? 598 HOH   A O    1 
HETATM 4242 O  O    . HOH   E 5 .   ? 17.65661 1.23484   -3.09902  1.000 69.63635  ? 599 HOH   A O    1 
HETATM 4243 O  O    . HOH   E 5 .   ? 39.68121 0.00000   -19.91983 0.50  59.55176  ? 600 HOH   A O    1 
HETATM 4244 O  O    . HOH   E 5 .   ? 50.92431 -5.60004  23.53048  1.000 62.44625  ? 601 HOH   A O    1 
# 
