data_9FTY
# 
_entry.id   9FTY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FTY         pdb_00009fty 10.2210/pdb9fty/pdb 
WWPDB D_1292139622 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FTY 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              daniele.de_sanctis@esrf.fr 
_pdbx_contact_author.name_first         Daniele 
_pdbx_contact_author.name_last          'de Sanctis' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0391-8290 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Orlans, J.'     1 0000-0002-6933-2287 
'Rose, S.L.'     2 0000-0003-4824-4066 
'Basu, S.'       3 0000-0001-6484-8236 
'de Sanctis, D.' 4 0000-0003-0391-8290 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Commun Chem' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2399-3669 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            8 
_citation.language                  ? 
_citation.page_first                6 
_citation.page_last                 6 
_citation.title                     
'Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s42004-024-01404-y 
_citation.pdbx_database_id_PubMed   39775172 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Orlans, J.'        1  ?                   
primary 'Rose, S.L.'        2  0000-0003-4824-4066 
primary 'Ferguson, G.'      3  0000-0003-2551-5994 
primary 'Oscarsson, M.'     4  ?                   
primary 'Homs Puron, A.'    5  ?                   
primary 'Beteva, A.'        6  ?                   
primary 'Debionne, S.'      7  ?                   
primary 'Theveneau, P.'     8  ?                   
primary 'Coquelle, N.'      9  ?                   
primary 'Kieffer, J.'       10 0000-0002-0730-6577 
primary 'Busca, P.'         11 ?                   
primary 'Sinoir, J.'        12 ?                   
primary 'Armijo, V.'        13 0009-0006-3243-8391 
primary 'Lopez Marrero, M.' 14 ?                   
primary 'Felisaz, F.'       15 ?                   
primary 'Papp, G.'          16 0000-0002-5702-843X 
primary 'Gonzalez, H.'      17 ?                   
primary 'Caserotto, H.'     18 ?                   
primary 'Dobias, F.'        19 ?                   
primary 'Gigmes, J.'        20 ?                   
primary 'Lebon, G.'         21 0000-0003-1162-5148 
primary 'Basu, S.'          22 0000-0001-6484-8236 
primary 'de Sanctis, D.'    23 0000-0003-0391-8290 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Proteinase K' 28958.791 1   3.4.21.64 ? ? ? 
2 non-polymer syn 'CALCIUM ION'  40.078    2   ?         ? ? ? 
3 non-polymer syn 'NITRATE ION'  62.005    1   ?         ? ? ? 
4 water       nat water          18.015    173 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Endopeptidase K,Tritirachium alkaline proteinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRDGNGHGTHCAGTVGSR
TYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQSSGVMVAVAAG
NNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLDIFGPGTDILSTWIGGSTRSISGTSMATPHVAGLAAYLMTL
GKTTAASACRYIADTANKGDLSNIPFGTVNLLAYNNYQA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRDGNGHGTHCAGTVGSR
TYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQSSGVMVAVAAG
NNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLDIFGPGTDILSTWIGGSTRSISGTSMATPHVAGLAAYLMTL
GKTTAASACRYIADTANKGDLSNIPFGTVNLLAYNNYQA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'CALCIUM ION' CA  
3 'NITRATE ION' NO3 
4 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   ALA n 
1 3   GLN n 
1 4   THR n 
1 5   ASN n 
1 6   ALA n 
1 7   PRO n 
1 8   TRP n 
1 9   GLY n 
1 10  LEU n 
1 11  ALA n 
1 12  ARG n 
1 13  ILE n 
1 14  SER n 
1 15  SER n 
1 16  THR n 
1 17  SER n 
1 18  PRO n 
1 19  GLY n 
1 20  THR n 
1 21  SER n 
1 22  THR n 
1 23  TYR n 
1 24  TYR n 
1 25  TYR n 
1 26  ASP n 
1 27  GLU n 
1 28  SER n 
1 29  ALA n 
1 30  GLY n 
1 31  GLN n 
1 32  GLY n 
1 33  SER n 
1 34  CYS n 
1 35  VAL n 
1 36  TYR n 
1 37  VAL n 
1 38  ILE n 
1 39  ASP n 
1 40  THR n 
1 41  GLY n 
1 42  ILE n 
1 43  GLU n 
1 44  ALA n 
1 45  SER n 
1 46  HIS n 
1 47  PRO n 
1 48  GLU n 
1 49  PHE n 
1 50  GLU n 
1 51  GLY n 
1 52  ARG n 
1 53  ALA n 
1 54  GLN n 
1 55  MET n 
1 56  VAL n 
1 57  LYS n 
1 58  THR n 
1 59  TYR n 
1 60  TYR n 
1 61  TYR n 
1 62  SER n 
1 63  SER n 
1 64  ARG n 
1 65  ASP n 
1 66  GLY n 
1 67  ASN n 
1 68  GLY n 
1 69  HIS n 
1 70  GLY n 
1 71  THR n 
1 72  HIS n 
1 73  CYS n 
1 74  ALA n 
1 75  GLY n 
1 76  THR n 
1 77  VAL n 
1 78  GLY n 
1 79  SER n 
1 80  ARG n 
1 81  THR n 
1 82  TYR n 
1 83  GLY n 
1 84  VAL n 
1 85  ALA n 
1 86  LYS n 
1 87  LYS n 
1 88  THR n 
1 89  GLN n 
1 90  LEU n 
1 91  PHE n 
1 92  GLY n 
1 93  VAL n 
1 94  LYS n 
1 95  VAL n 
1 96  LEU n 
1 97  ASP n 
1 98  ASP n 
1 99  ASN n 
1 100 GLY n 
1 101 SER n 
1 102 GLY n 
1 103 GLN n 
1 104 TYR n 
1 105 SER n 
1 106 THR n 
1 107 ILE n 
1 108 ILE n 
1 109 ALA n 
1 110 GLY n 
1 111 MET n 
1 112 ASP n 
1 113 PHE n 
1 114 VAL n 
1 115 ALA n 
1 116 SER n 
1 117 ASP n 
1 118 LYS n 
1 119 ASN n 
1 120 ASN n 
1 121 ARG n 
1 122 ASN n 
1 123 CYS n 
1 124 PRO n 
1 125 LYS n 
1 126 GLY n 
1 127 VAL n 
1 128 VAL n 
1 129 ALA n 
1 130 SER n 
1 131 LEU n 
1 132 SER n 
1 133 LEU n 
1 134 GLY n 
1 135 GLY n 
1 136 GLY n 
1 137 TYR n 
1 138 SER n 
1 139 SER n 
1 140 SER n 
1 141 VAL n 
1 142 ASN n 
1 143 SER n 
1 144 ALA n 
1 145 ALA n 
1 146 ALA n 
1 147 ARG n 
1 148 LEU n 
1 149 GLN n 
1 150 SER n 
1 151 SER n 
1 152 GLY n 
1 153 VAL n 
1 154 MET n 
1 155 VAL n 
1 156 ALA n 
1 157 VAL n 
1 158 ALA n 
1 159 ALA n 
1 160 GLY n 
1 161 ASN n 
1 162 ASN n 
1 163 ASN n 
1 164 ALA n 
1 165 ASP n 
1 166 ALA n 
1 167 ARG n 
1 168 ASN n 
1 169 TYR n 
1 170 SER n 
1 171 PRO n 
1 172 ALA n 
1 173 SER n 
1 174 GLU n 
1 175 PRO n 
1 176 SER n 
1 177 VAL n 
1 178 CYS n 
1 179 THR n 
1 180 VAL n 
1 181 GLY n 
1 182 ALA n 
1 183 SER n 
1 184 ASP n 
1 185 ARG n 
1 186 TYR n 
1 187 ASP n 
1 188 ARG n 
1 189 ARG n 
1 190 SER n 
1 191 SER n 
1 192 PHE n 
1 193 SER n 
1 194 ASN n 
1 195 TYR n 
1 196 GLY n 
1 197 SER n 
1 198 VAL n 
1 199 LEU n 
1 200 ASP n 
1 201 ILE n 
1 202 PHE n 
1 203 GLY n 
1 204 PRO n 
1 205 GLY n 
1 206 THR n 
1 207 ASP n 
1 208 ILE n 
1 209 LEU n 
1 210 SER n 
1 211 THR n 
1 212 TRP n 
1 213 ILE n 
1 214 GLY n 
1 215 GLY n 
1 216 SER n 
1 217 THR n 
1 218 ARG n 
1 219 SER n 
1 220 ILE n 
1 221 SER n 
1 222 GLY n 
1 223 THR n 
1 224 SER n 
1 225 MET n 
1 226 ALA n 
1 227 THR n 
1 228 PRO n 
1 229 HIS n 
1 230 VAL n 
1 231 ALA n 
1 232 GLY n 
1 233 LEU n 
1 234 ALA n 
1 235 ALA n 
1 236 TYR n 
1 237 LEU n 
1 238 MET n 
1 239 THR n 
1 240 LEU n 
1 241 GLY n 
1 242 LYS n 
1 243 THR n 
1 244 THR n 
1 245 ALA n 
1 246 ALA n 
1 247 SER n 
1 248 ALA n 
1 249 CYS n 
1 250 ARG n 
1 251 TYR n 
1 252 ILE n 
1 253 ALA n 
1 254 ASP n 
1 255 THR n 
1 256 ALA n 
1 257 ASN n 
1 258 LYS n 
1 259 GLY n 
1 260 ASP n 
1 261 LEU n 
1 262 SER n 
1 263 ASN n 
1 264 ILE n 
1 265 PRO n 
1 266 PHE n 
1 267 GLY n 
1 268 THR n 
1 269 VAL n 
1 270 ASN n 
1 271 LEU n 
1 272 LEU n 
1 273 ALA n 
1 274 TYR n 
1 275 ASN n 
1 276 ASN n 
1 277 TYR n 
1 278 GLN n 
1 279 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   279 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PROK 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Parengyodontium album' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     37998 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Komagataella pastoris' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4922 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CA  non-polymer         . 'CALCIUM ION'   ? 'Ca 2'           40.078  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
NO3 non-polymer         . 'NITRATE ION'   ? 'N O3 -1'        62.005  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   GLN 3   3   3   GLN GLN A . n 
A 1 4   THR 4   4   4   THR THR A . n 
A 1 5   ASN 5   5   5   ASN ASN A . n 
A 1 6   ALA 6   6   6   ALA ALA A . n 
A 1 7   PRO 7   7   7   PRO PRO A . n 
A 1 8   TRP 8   8   8   TRP TRP A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  ARG 12  12  12  ARG ARG A . n 
A 1 13  ILE 13  13  13  ILE ILE A . n 
A 1 14  SER 14  14  14  SER SER A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  THR 16  16  16  THR THR A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  PRO 18  18  18  PRO PRO A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  THR 20  20  20  THR THR A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  THR 22  22  22  THR THR A . n 
A 1 23  TYR 23  23  23  TYR TYR A . n 
A 1 24  TYR 24  24  24  TYR TYR A . n 
A 1 25  TYR 25  25  25  TYR TYR A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  GLU 27  27  27  GLU GLU A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  ALA 29  29  29  ALA ALA A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  CYS 34  34  34  CYS CYS A . n 
A 1 35  VAL 35  35  35  VAL VAL A . n 
A 1 36  TYR 36  36  36  TYR TYR A . n 
A 1 37  VAL 37  37  37  VAL VAL A . n 
A 1 38  ILE 38  38  38  ILE ILE A . n 
A 1 39  ASP 39  39  39  ASP ASP A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  SER 45  45  45  SER SER A . n 
A 1 46  HIS 46  46  46  HIS HIS A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  GLU 48  48  48  GLU GLU A . n 
A 1 49  PHE 49  49  49  PHE PHE A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  ARG 52  52  52  ARG ARG A . n 
A 1 53  ALA 53  53  53  ALA ALA A . n 
A 1 54  GLN 54  54  54  GLN GLN A . n 
A 1 55  MET 55  55  55  MET MET A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  LYS 57  57  57  LYS LYS A . n 
A 1 58  THR 58  58  58  THR THR A . n 
A 1 59  TYR 59  59  59  TYR TYR A . n 
A 1 60  TYR 60  60  60  TYR TYR A . n 
A 1 61  TYR 61  61  61  TYR TYR A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  SER 63  63  63  SER SER A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  ASN 67  67  67  ASN ASN A . n 
A 1 68  GLY 68  68  68  GLY GLY A . n 
A 1 69  HIS 69  69  69  HIS HIS A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  HIS 72  72  72  HIS HIS A . n 
A 1 73  CYS 73  73  73  CYS CYS A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  THR 76  76  76  THR THR A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  ARG 80  80  80  ARG ARG A . n 
A 1 81  THR 81  81  81  THR THR A . n 
A 1 82  TYR 82  82  82  TYR TYR A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ALA 85  85  85  ALA ALA A . n 
A 1 86  LYS 86  86  86  LYS LYS A . n 
A 1 87  LYS 87  87  87  LYS LYS A . n 
A 1 88  THR 88  88  88  THR THR A . n 
A 1 89  GLN 89  89  89  GLN GLN A . n 
A 1 90  LEU 90  90  90  LEU LEU A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  LYS 94  94  94  LYS LYS A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  ASP 97  97  97  ASP ASP A . n 
A 1 98  ASP 98  98  98  ASP ASP A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 SER 101 101 101 SER SER A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 GLN 103 103 103 GLN GLN A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ILE 108 108 108 ILE ILE A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 GLY 110 110 110 GLY GLY A . n 
A 1 111 MET 111 111 111 MET MET A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 ASN 119 119 119 ASN ASN A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 ARG 121 121 121 ARG ARG A . n 
A 1 122 ASN 122 122 122 ASN ASN A . n 
A 1 123 CYS 123 123 123 CYS CYS A . n 
A 1 124 PRO 124 124 124 PRO PRO A . n 
A 1 125 LYS 125 125 125 LYS LYS A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 GLY 135 135 135 GLY GLY A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 SER 140 140 140 SER SER A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 ASN 142 142 142 ASN ASN A . n 
A 1 143 SER 143 143 143 SER SER A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ARG 147 147 147 ARG ARG A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 GLN 149 149 149 GLN GLN A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 SER 151 151 151 SER SER A . n 
A 1 152 GLY 152 152 152 GLY GLY A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 MET 154 154 154 MET MET A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 ALA 159 159 159 ALA ALA A . n 
A 1 160 GLY 160 160 160 GLY GLY A . n 
A 1 161 ASN 161 161 161 ASN ASN A . n 
A 1 162 ASN 162 162 162 ASN ASN A . n 
A 1 163 ASN 163 163 163 ASN ASN A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 ASN 168 168 168 ASN ASN A . n 
A 1 169 TYR 169 169 169 TYR TYR A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 SER 173 173 173 SER SER A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 PRO 175 175 175 PRO PRO A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 VAL 177 177 177 VAL VAL A . n 
A 1 178 CYS 178 178 178 CYS CYS A . n 
A 1 179 THR 179 179 179 THR THR A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 ASP 184 184 184 ASP ASP A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 ASP 187 187 187 ASP ASP A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 ARG 189 189 189 ARG ARG A . n 
A 1 190 SER 190 190 190 SER SER A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 PHE 192 192 192 PHE PHE A . n 
A 1 193 SER 193 193 193 SER SER A . n 
A 1 194 ASN 194 194 194 ASN ASN A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 GLY 196 196 196 GLY GLY A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 GLY 203 203 203 GLY GLY A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 GLY 205 205 205 GLY GLY A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ASP 207 207 207 ASP ASP A . n 
A 1 208 ILE 208 208 208 ILE ILE A . n 
A 1 209 LEU 209 209 209 LEU LEU A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 TRP 212 212 212 TRP TRP A . n 
A 1 213 ILE 213 213 213 ILE ILE A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 THR 217 217 217 THR THR A . n 
A 1 218 ARG 218 218 218 ARG ARG A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 ILE 220 220 220 ILE ILE A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 THR 223 223 223 THR THR A . n 
A 1 224 SER 224 224 224 SER SER A . n 
A 1 225 MET 225 225 225 MET MET A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 HIS 229 229 229 HIS HIS A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 GLY 232 232 232 GLY GLY A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 TYR 236 236 236 TYR TYR A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 MET 238 238 238 MET MET A . n 
A 1 239 THR 239 239 239 THR THR A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 LYS 242 242 242 LYS LYS A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 CYS 249 249 249 CYS CYS A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 TYR 251 251 251 TYR TYR A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 ASP 254 254 254 ASP ASP A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 ASN 257 257 257 ASN ASN A . n 
A 1 258 LYS 258 258 258 LYS LYS A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 ASP 260 260 260 ASP ASP A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 SER 262 262 262 SER SER A . n 
A 1 263 ASN 263 263 263 ASN ASN A . n 
A 1 264 ILE 264 264 264 ILE ILE A . n 
A 1 265 PRO 265 265 265 PRO PRO A . n 
A 1 266 PHE 266 266 266 PHE PHE A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 VAL 269 269 269 VAL VAL A . n 
A 1 270 ASN 270 270 270 ASN ASN A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 TYR 274 274 274 TYR TYR A . n 
A 1 275 ASN 275 275 275 ASN ASN A . n 
A 1 276 ASN 276 276 276 ASN ASN A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 GLN 278 278 278 GLN GLN A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 CA  1   501 501 CA  CA  A . 
C 2 CA  1   502 502 CA  CA  A . 
D 3 NO3 1   503 503 NO3 NO3 A . 
E 4 HOH 1   601 44  HOH HOH A . 
E 4 HOH 2   602 141 HOH HOH A . 
E 4 HOH 3   603 142 HOH HOH A . 
E 4 HOH 4   604 112 HOH HOH A . 
E 4 HOH 5   605 100 HOH HOH A . 
E 4 HOH 6   606 140 HOH HOH A . 
E 4 HOH 7   607 437 HOH HOH A . 
E 4 HOH 8   608 297 HOH HOH A . 
E 4 HOH 9   609 317 HOH HOH A . 
E 4 HOH 10  610 298 HOH HOH A . 
E 4 HOH 11  611 23  HOH HOH A . 
E 4 HOH 12  612 145 HOH HOH A . 
E 4 HOH 13  613 190 HOH HOH A . 
E 4 HOH 14  614 68  HOH HOH A . 
E 4 HOH 15  615 416 HOH HOH A . 
E 4 HOH 16  616 12  HOH HOH A . 
E 4 HOH 17  617 163 HOH HOH A . 
E 4 HOH 18  618 4   HOH HOH A . 
E 4 HOH 19  619 350 HOH HOH A . 
E 4 HOH 20  620 158 HOH HOH A . 
E 4 HOH 21  621 74  HOH HOH A . 
E 4 HOH 22  622 315 HOH HOH A . 
E 4 HOH 23  623 5   HOH HOH A . 
E 4 HOH 24  624 80  HOH HOH A . 
E 4 HOH 25  625 19  HOH HOH A . 
E 4 HOH 26  626 55  HOH HOH A . 
E 4 HOH 27  627 22  HOH HOH A . 
E 4 HOH 28  628 67  HOH HOH A . 
E 4 HOH 29  629 38  HOH HOH A . 
E 4 HOH 30  630 97  HOH HOH A . 
E 4 HOH 31  631 151 HOH HOH A . 
E 4 HOH 32  632 61  HOH HOH A . 
E 4 HOH 33  633 436 HOH HOH A . 
E 4 HOH 34  634 2   HOH HOH A . 
E 4 HOH 35  635 13  HOH HOH A . 
E 4 HOH 36  636 29  HOH HOH A . 
E 4 HOH 37  637 175 HOH HOH A . 
E 4 HOH 38  638 8   HOH HOH A . 
E 4 HOH 39  639 274 HOH HOH A . 
E 4 HOH 40  640 252 HOH HOH A . 
E 4 HOH 41  641 196 HOH HOH A . 
E 4 HOH 42  642 46  HOH HOH A . 
E 4 HOH 43  643 167 HOH HOH A . 
E 4 HOH 44  644 435 HOH HOH A . 
E 4 HOH 45  645 39  HOH HOH A . 
E 4 HOH 46  646 26  HOH HOH A . 
E 4 HOH 47  647 42  HOH HOH A . 
E 4 HOH 48  648 169 HOH HOH A . 
E 4 HOH 49  649 7   HOH HOH A . 
E 4 HOH 50  650 102 HOH HOH A . 
E 4 HOH 51  651 183 HOH HOH A . 
E 4 HOH 52  652 293 HOH HOH A . 
E 4 HOH 53  653 218 HOH HOH A . 
E 4 HOH 54  654 73  HOH HOH A . 
E 4 HOH 55  655 36  HOH HOH A . 
E 4 HOH 56  656 336 HOH HOH A . 
E 4 HOH 57  657 56  HOH HOH A . 
E 4 HOH 58  658 18  HOH HOH A . 
E 4 HOH 59  659 9   HOH HOH A . 
E 4 HOH 60  660 6   HOH HOH A . 
E 4 HOH 61  661 21  HOH HOH A . 
E 4 HOH 62  662 139 HOH HOH A . 
E 4 HOH 63  663 27  HOH HOH A . 
E 4 HOH 64  664 225 HOH HOH A . 
E 4 HOH 65  665 198 HOH HOH A . 
E 4 HOH 66  666 205 HOH HOH A . 
E 4 HOH 67  667 47  HOH HOH A . 
E 4 HOH 68  668 20  HOH HOH A . 
E 4 HOH 69  669 368 HOH HOH A . 
E 4 HOH 70  670 180 HOH HOH A . 
E 4 HOH 71  671 58  HOH HOH A . 
E 4 HOH 72  672 49  HOH HOH A . 
E 4 HOH 73  673 16  HOH HOH A . 
E 4 HOH 74  674 152 HOH HOH A . 
E 4 HOH 75  675 125 HOH HOH A . 
E 4 HOH 76  676 136 HOH HOH A . 
E 4 HOH 77  677 104 HOH HOH A . 
E 4 HOH 78  678 123 HOH HOH A . 
E 4 HOH 79  679 124 HOH HOH A . 
E 4 HOH 80  680 65  HOH HOH A . 
E 4 HOH 81  681 35  HOH HOH A . 
E 4 HOH 82  682 66  HOH HOH A . 
E 4 HOH 83  683 14  HOH HOH A . 
E 4 HOH 84  684 51  HOH HOH A . 
E 4 HOH 85  685 32  HOH HOH A . 
E 4 HOH 86  686 433 HOH HOH A . 
E 4 HOH 87  687 15  HOH HOH A . 
E 4 HOH 88  688 31  HOH HOH A . 
E 4 HOH 89  689 340 HOH HOH A . 
E 4 HOH 90  690 239 HOH HOH A . 
E 4 HOH 91  691 63  HOH HOH A . 
E 4 HOH 92  692 172 HOH HOH A . 
E 4 HOH 93  693 113 HOH HOH A . 
E 4 HOH 94  694 34  HOH HOH A . 
E 4 HOH 95  695 259 HOH HOH A . 
E 4 HOH 96  696 291 HOH HOH A . 
E 4 HOH 97  697 214 HOH HOH A . 
E 4 HOH 98  698 17  HOH HOH A . 
E 4 HOH 99  699 11  HOH HOH A . 
E 4 HOH 100 700 48  HOH HOH A . 
E 4 HOH 101 701 211 HOH HOH A . 
E 4 HOH 102 702 3   HOH HOH A . 
E 4 HOH 103 703 93  HOH HOH A . 
E 4 HOH 104 704 165 HOH HOH A . 
E 4 HOH 105 705 30  HOH HOH A . 
E 4 HOH 106 706 314 HOH HOH A . 
E 4 HOH 107 707 40  HOH HOH A . 
E 4 HOH 108 708 24  HOH HOH A . 
E 4 HOH 109 709 144 HOH HOH A . 
E 4 HOH 110 710 153 HOH HOH A . 
E 4 HOH 111 711 313 HOH HOH A . 
E 4 HOH 112 712 182 HOH HOH A . 
E 4 HOH 113 713 10  HOH HOH A . 
E 4 HOH 114 714 339 HOH HOH A . 
E 4 HOH 115 715 84  HOH HOH A . 
E 4 HOH 116 716 275 HOH HOH A . 
E 4 HOH 117 717 91  HOH HOH A . 
E 4 HOH 118 718 162 HOH HOH A . 
E 4 HOH 119 719 330 HOH HOH A . 
E 4 HOH 120 720 184 HOH HOH A . 
E 4 HOH 121 721 177 HOH HOH A . 
E 4 HOH 122 722 173 HOH HOH A . 
E 4 HOH 123 723 54  HOH HOH A . 
E 4 HOH 124 724 400 HOH HOH A . 
E 4 HOH 125 725 285 HOH HOH A . 
E 4 HOH 126 726 351 HOH HOH A . 
E 4 HOH 127 727 43  HOH HOH A . 
E 4 HOH 128 728 415 HOH HOH A . 
E 4 HOH 129 729 52  HOH HOH A . 
E 4 HOH 130 730 111 HOH HOH A . 
E 4 HOH 131 731 254 HOH HOH A . 
E 4 HOH 132 732 185 HOH HOH A . 
E 4 HOH 133 733 394 HOH HOH A . 
E 4 HOH 134 734 159 HOH HOH A . 
E 4 HOH 135 735 25  HOH HOH A . 
E 4 HOH 136 736 309 HOH HOH A . 
E 4 HOH 137 737 161 HOH HOH A . 
E 4 HOH 138 738 229 HOH HOH A . 
E 4 HOH 139 739 70  HOH HOH A . 
E 4 HOH 140 740 284 HOH HOH A . 
E 4 HOH 141 741 423 HOH HOH A . 
E 4 HOH 142 742 362 HOH HOH A . 
E 4 HOH 143 743 170 HOH HOH A . 
E 4 HOH 144 744 355 HOH HOH A . 
E 4 HOH 145 745 277 HOH HOH A . 
E 4 HOH 146 746 240 HOH HOH A . 
E 4 HOH 147 747 219 HOH HOH A . 
E 4 HOH 148 748 290 HOH HOH A . 
E 4 HOH 149 749 363 HOH HOH A . 
E 4 HOH 150 750 420 HOH HOH A . 
E 4 HOH 151 751 76  HOH HOH A . 
E 4 HOH 152 752 407 HOH HOH A . 
E 4 HOH 153 753 282 HOH HOH A . 
E 4 HOH 154 754 402 HOH HOH A . 
E 4 HOH 155 755 57  HOH HOH A . 
E 4 HOH 156 756 326 HOH HOH A . 
E 4 HOH 157 757 226 HOH HOH A . 
E 4 HOH 158 758 227 HOH HOH A . 
E 4 HOH 159 759 281 HOH HOH A . 
E 4 HOH 160 760 53  HOH HOH A . 
E 4 HOH 161 761 305 HOH HOH A . 
E 4 HOH 162 762 384 HOH HOH A . 
E 4 HOH 163 763 160 HOH HOH A . 
E 4 HOH 164 764 264 HOH HOH A . 
E 4 HOH 165 765 224 HOH HOH A . 
E 4 HOH 166 766 127 HOH HOH A . 
E 4 HOH 167 767 134 HOH HOH A . 
E 4 HOH 168 768 331 HOH HOH A . 
E 4 HOH 169 769 406 HOH HOH A . 
E 4 HOH 170 770 108 HOH HOH A . 
E 4 HOH 171 771 216 HOH HOH A . 
E 4 HOH 172 772 377 HOH HOH A . 
E 4 HOH 173 773 381 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ASN 5   ? CG  ? A ASN 5   CG  
2  1 Y 1 A ASN 5   ? OD1 ? A ASN 5   OD1 
3  1 Y 1 A ASN 5   ? ND2 ? A ASN 5   ND2 
4  1 Y 1 A GLN 31  ? CG  ? A GLN 31  CG  
5  1 Y 1 A GLN 31  ? CD  ? A GLN 31  CD  
6  1 Y 1 A GLN 31  ? OE1 ? A GLN 31  OE1 
7  1 Y 1 A GLN 31  ? NE2 ? A GLN 31  NE2 
8  1 Y 1 A ARG 64  ? CG  ? A ARG 64  CG  
9  1 Y 1 A ARG 64  ? CD  ? A ARG 64  CD  
10 1 Y 1 A ARG 64  ? NE  ? A ARG 64  NE  
11 1 Y 1 A ARG 64  ? CZ  ? A ARG 64  CZ  
12 1 Y 1 A ARG 64  ? NH1 ? A ARG 64  NH1 
13 1 Y 1 A ARG 64  ? NH2 ? A ARG 64  NH2 
14 1 Y 1 A ARG 80  ? CG  ? A ARG 80  CG  
15 1 Y 1 A ARG 80  ? CD  ? A ARG 80  CD  
16 1 Y 1 A ARG 80  ? NE  ? A ARG 80  NE  
17 1 Y 1 A ARG 80  ? CZ  ? A ARG 80  CZ  
18 1 Y 1 A ARG 80  ? NH1 ? A ARG 80  NH1 
19 1 Y 1 A ARG 80  ? NH2 ? A ARG 80  NH2 
20 1 Y 1 A GLN 103 ? CG  ? A GLN 103 CG  
21 1 Y 1 A GLN 103 ? CD  ? A GLN 103 CD  
22 1 Y 1 A GLN 103 ? OE1 ? A GLN 103 OE1 
23 1 Y 1 A GLN 103 ? NE2 ? A GLN 103 NE2 
24 1 Y 1 A ARG 167 ? CG  ? A ARG 167 CG  
25 1 Y 1 A ARG 167 ? CD  ? A ARG 167 CD  
26 1 Y 1 A ARG 167 ? NE  ? A ARG 167 NE  
27 1 Y 1 A ARG 167 ? CZ  ? A ARG 167 CZ  
28 1 Y 1 A ARG 167 ? NH1 ? A ARG 167 NH1 
29 1 Y 1 A ARG 167 ? NH2 ? A ARG 167 NH2 
30 1 Y 1 A ARG 250 ? CG  ? A ARG 250 CG  
31 1 Y 1 A ARG 250 ? CD  ? A ARG 250 CD  
32 1 Y 1 A ARG 250 ? NE  ? A ARG 250 NE  
33 1 Y 1 A ARG 250 ? CZ  ? A ARG 250 CZ  
34 1 Y 1 A ARG 250 ? NH1 ? A ARG 250 NH1 
35 1 Y 1 A ARG 250 ? NH2 ? A ARG 250 NH2 
36 1 Y 1 A LYS 258 ? CG  ? A LYS 258 CG  
37 1 Y 1 A LYS 258 ? CD  ? A LYS 258 CD  
38 1 Y 1 A LYS 258 ? CE  ? A LYS 258 CE  
39 1 Y 1 A LYS 258 ? NZ  ? A LYS 258 NZ  
40 1 Y 1 A GLN 278 ? CG  ? A GLN 278 CG  
41 1 Y 1 A GLN 278 ? CD  ? A GLN 278 CD  
42 1 Y 1 A GLN 278 ? OE1 ? A GLN 278 OE1 
43 1 Y 1 A GLN 278 ? NE2 ? A GLN 278 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.21_5207 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FTY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     68.720 
_cell.length_a_esd                 ? 
_cell.length_b                     68.720 
_cell.length_b_esd                 ? 
_cell.length_c                     108.970 
_cell.length_c_esd                 ? 
_cell.volume                       514604.112 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FTY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                96 
_symmetry.space_group_name_Hall            'P 4nw 2abw' 
_symmetry.space_group_name_H-M             'P 43 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FTY 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.23 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          44.73 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M MES pH 6.5, 0.5 M sodium nitrate, 0.1 M calcium chloride' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'PSI JUNGFRAU 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-03-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.072 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID29' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.072 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID29 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          17.29 
_reflns.entry_id                                       9FTY 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2 
_reflns.d_resolution_low                               58.13 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     18372 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                133 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          3.94 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   0.9653 
_reflns.pdbx_R_split                                   0.3207 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2 
_reflns_shell.d_res_low                                     2.03 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             889 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  0.7465 
_reflns_shell.pdbx_R_split                                  1.2812 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               15.87 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FTY 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.00 
_refine.ls_d_res_low                             58.13 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     18251 
_refine.ls_number_reflns_R_free                  1823 
_refine.ls_number_reflns_R_work                  16428 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.65 
_refine.ls_percent_reflns_R_free                 9.99 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2425 
_refine.ls_R_factor_R_free                       0.2622 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2403 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.8570 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3049 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.00 
_refine_hist.d_res_low                        58.13 
_refine_hist.number_atoms_solvent             173 
_refine_hist.number_atoms_total               2168 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1989 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         6 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0015  ? 2031 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4214  ? 2767 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0403  ? 312  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0031  ? 365  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 10.5200 ? 683  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.00 2.05  . . 138 1242 99.78 . . . . 0.3530 . . . . . . . . . . . 0.3759 
'X-RAY DIFFRACTION' 2.05 2.11  . . 140 1247 99.57 . . . . 0.3225 . . . . . . . . . . . 0.3761 
'X-RAY DIFFRACTION' 2.11 2.18  . . 136 1217 99.63 . . . . 0.3023 . . . . . . . . . . . 0.3208 
'X-RAY DIFFRACTION' 2.18 2.26  . . 137 1240 99.93 . . . . 0.2639 . . . . . . . . . . . 0.3140 
'X-RAY DIFFRACTION' 2.26 2.35  . . 138 1243 99.93 . . . . 0.2593 . . . . . . . . . . . 0.2952 
'X-RAY DIFFRACTION' 2.35 2.46  . . 138 1247 99.86 . . . . 0.2594 . . . . . . . . . . . 0.2937 
'X-RAY DIFFRACTION' 2.46 2.59  . . 139 1249 99.86 . . . . 0.2520 . . . . . . . . . . . 0.2720 
'X-RAY DIFFRACTION' 2.59 2.75  . . 139 1263 99.57 . . . . 0.2408 . . . . . . . . . . . 0.2586 
'X-RAY DIFFRACTION' 2.75 2.96  . . 140 1248 99.86 . . . . 0.2456 . . . . . . . . . . . 0.2364 
'X-RAY DIFFRACTION' 2.96 3.26  . . 141 1271 99.72 . . . . 0.2298 . . . . . . . . . . . 0.2694 
'X-RAY DIFFRACTION' 3.26 3.73  . . 138 1276 99.51 . . . . 0.2082 . . . . . . . . . . . 0.2458 
'X-RAY DIFFRACTION' 3.73 4.70  . . 143 1295 99.24 . . . . 0.1880 . . . . . . . . . . . 0.1933 
'X-RAY DIFFRACTION' 4.70 58.13 . . 156 1390 99.23 . . . . 0.2166 . . . . . . . . . . . 0.2140 
# 
_struct.entry_id                     9FTY 
_struct.title                        
'Serial microseconds crystallography at ID29 using fixed-target (small foils): Proteinase K with 20 um spacing between X-ray pulses' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FTY 
_struct_keywords.text            
'Serial crystallography, serial microsecond crystallography, room temperature, ID29, ESRF-EBS, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PRTK_PARAQ 
_struct_ref.pdbx_db_accession          P06873 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRDGNGHGTHCAGTVGSR
TYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQSSGVMVAVAAG
NNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLDIFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTL
GKTTAASACRYIADTANKGDLSNIPFGTVNLLAYNNYQA
;
_struct_ref.pdbx_align_begin           106 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9FTY 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 279 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P06873 
_struct_ref_seq.db_align_beg                  106 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  384 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       279 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9FTY 
_struct_ref_seq_dif.mon_id                       ASP 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      207 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P06873 
_struct_ref_seq_dif.db_mon_id                    SER 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          312 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            207 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 PRO A 7   ? ILE A 13  ? PRO A 7   ILE A 13  1 ? 7  
HELX_P HELX_P2 AA2 HIS A 46  ? GLU A 50  ? HIS A 46  GLU A 50  5 ? 5  
HELX_P HELX_P3 AA3 GLY A 68  ? SER A 79  ? GLY A 68  SER A 79  1 ? 12 
HELX_P HELX_P4 AA4 GLN A 103 ? LYS A 118 ? GLN A 103 LYS A 118 1 ? 16 
HELX_P HELX_P5 AA5 ASN A 119 ? ARG A 121 ? ASN A 119 ARG A 121 5 ? 3  
HELX_P HELX_P6 AA6 SER A 138 ? SER A 151 ? SER A 138 SER A 151 1 ? 14 
HELX_P HELX_P7 AA7 ASP A 165 ? ARG A 167 ? ASP A 165 ARG A 167 5 ? 3  
HELX_P HELX_P8 AA8 GLY A 222 ? LEU A 240 ? GLY A 222 LEU A 240 1 ? 19 
HELX_P HELX_P9 AA9 SER A 247 ? THR A 255 ? SER A 247 THR A 255 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 34  SG  ? ? ? 1_555 A CYS 123 SG ? ? A CYS 34  A CYS 123 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf2  disulf ? ? A CYS 178 SG  ? ? ? 1_555 A CYS 249 SG ? ? A CYS 178 A CYS 249 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
metalc1  metalc ? ? A THR 16  O   ? ? ? 1_555 C CA  .   CA ? ? A THR 16  A CA  502 1_555 ? ? ? ? ? ? ? 2.431 ? ? 
metalc2  metalc ? ? A PRO 175 O   ? ? ? 1_555 B CA  .   CA ? ? A PRO 175 A CA  501 1_555 ? ? ? ? ? ? ? 2.426 ? ? 
metalc3  metalc ? ? A VAL 177 O   ? ? ? 1_555 B CA  .   CA ? ? A VAL 177 A CA  501 1_555 ? ? ? ? ? ? ? 2.400 ? ? 
metalc4  metalc ? ? A ASP 200 OD1 ? ? ? 1_555 B CA  .   CA ? ? A ASP 200 A CA  501 1_555 ? ? ? ? ? ? ? 2.604 ? ? 
metalc5  metalc ? ? A ASP 200 OD2 ? ? ? 1_555 B CA  .   CA ? ? A ASP 200 A CA  501 1_555 ? ? ? ? ? ? ? 2.488 ? ? 
metalc6  metalc ? ? A ASP 260 OD1 ? ? ? 1_555 C CA  .   CA ? ? A ASP 260 A CA  502 1_555 ? ? ? ? ? ? ? 2.648 ? ? 
metalc7  metalc ? ? A ASP 260 OD2 ? ? ? 1_555 C CA  .   CA ? ? A ASP 260 A CA  502 1_555 ? ? ? ? ? ? ? 2.319 ? ? 
metalc8  metalc ? ? B CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  501 A HOH 618 1_555 ? ? ? ? ? ? ? 2.592 ? ? 
metalc9  metalc ? ? B CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  501 A HOH 646 1_555 ? ? ? ? ? ? ? 2.724 ? ? 
metalc10 metalc ? ? B CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  501 A HOH 713 1_555 ? ? ? ? ? ? ? 2.657 ? ? 
metalc11 metalc ? ? B CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  501 A HOH 727 1_555 ? ? ? ? ? ? ? 2.566 ? ? 
metalc12 metalc ? ? C CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  502 A HOH 657 1_555 ? ? ? ? ? ? ? 2.338 ? ? 
metalc13 metalc ? ? C CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  502 A HOH 707 1_555 ? ? ? ? ? ? ? 2.645 ? ? 
metalc14 metalc ? ? C CA  .   CA  ? ? ? 1_555 E HOH .   O  ? ? A CA  502 A HOH 735 1_555 ? ? ? ? ? ? ? 2.399 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O   ? A THR 16  ? A THR 16  ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 OD1 ? A ASP 260 ? A ASP 260 ? 1_555 139.3 ? 
2  O   ? A THR 16  ? A THR 16  ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 OD2 ? A ASP 260 ? A ASP 260 ? 1_555 87.3  ? 
3  OD1 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 OD2 ? A ASP 260 ? A ASP 260 ? 1_555 52.0  ? 
4  O   ? A THR 16  ? A THR 16  ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 657 ? 1_555 74.9  ? 
5  OD1 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 657 ? 1_555 93.1  ? 
6  OD2 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 657 ? 1_555 76.8  ? 
7  O   ? A THR 16  ? A THR 16  ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 707 ? 1_555 72.3  ? 
8  OD1 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 707 ? 1_555 148.3 ? 
9  OD2 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 707 ? 1_555 159.3 ? 
10 O   ? E HOH .   ? A HOH 657 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 707 ? 1_555 100.5 ? 
11 O   ? A THR 16  ? A THR 16  ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 735 ? 1_555 88.9  ? 
12 OD1 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 735 ? 1_555 94.2  ? 
13 OD2 ? A ASP 260 ? A ASP 260 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 735 ? 1_555 95.1  ? 
14 O   ? E HOH .   ? A HOH 657 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 735 ? 1_555 162.1 ? 
15 O   ? E HOH .   ? A HOH 707 ? 1_555 CA ? C CA . ? A CA 502 ? 1_555 O   ? E HOH .   ? A HOH 735 ? 1_555 81.3  ? 
16 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? A VAL 177 ? A VAL 177 ? 1_555 87.6  ? 
17 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 148.3 ? 
18 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 119.4 ? 
19 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 160.1 ? 
20 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 78.9  ? 
21 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 51.0  ? 
22 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 618 ? 1_555 83.2  ? 
23 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 618 ? 1_555 68.0  ? 
24 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 618 ? 1_555 120.7 ? 
25 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 618 ? 1_555 78.2  ? 
26 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 646 ? 1_555 94.8  ? 
27 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 646 ? 1_555 142.7 ? 
28 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 646 ? 1_555 74.1  ? 
29 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 646 ? 1_555 87.4  ? 
30 O   ? E HOH .   ? A HOH 618 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 646 ? 1_555 75.2  ? 
31 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 73.2  ? 
32 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 143.5 ? 
33 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 75.1  ? 
34 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 125.9 ? 
35 O   ? E HOH .   ? A HOH 618 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 136.8 ? 
36 O   ? E HOH .   ? A HOH 646 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 713 ? 1_555 71.3  ? 
37 O   ? A PRO 175 ? A PRO 175 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 86.3  ? 
38 O   ? A VAL 177 ? A VAL 177 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 79.4  ? 
39 OD1 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 83.2  ? 
40 OD2 ? A ASP 200 ? A ASP 200 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 105.3 ? 
41 O   ? E HOH .   ? A HOH 618 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 146.0 ? 
42 O   ? E HOH .   ? A HOH 646 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 138.0 ? 
43 O   ? E HOH .   ? A HOH 713 ? 1_555 CA ? B CA . ? A CA 501 ? 1_555 O   ? E HOH .   ? A HOH 727 ? 1_555 68.8  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 34  ? CYS A 123 ? CYS A 34  ? 1_555 CYS A 123 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 178 ? CYS A 249 ? CYS A 178 ? 1_555 CYS A 249 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          SER 
_struct_mon_prot_cis.label_seq_id           170 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           SER 
_struct_mon_prot_cis.auth_seq_id            170 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    171 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     171 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.63 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 7 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? parallel      
AA2 6 7 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 2   ? GLN A 3   ? ALA A 2   GLN A 3   
AA1 2 TYR A 23  ? TYR A 24  ? TYR A 23  TYR A 24  
AA2 1 ALA A 53  ? THR A 58  ? ALA A 53  THR A 58  
AA2 2 GLN A 89  ? LYS A 94  ? GLN A 89  LYS A 94  
AA2 3 SER A 33  ? ASP A 39  ? SER A 33  ASP A 39  
AA2 4 GLY A 126 ? LEU A 131 ? GLY A 126 LEU A 131 
AA2 5 MET A 154 ? ALA A 158 ? MET A 154 ALA A 158 
AA2 6 CYS A 178 ? SER A 183 ? CYS A 178 SER A 183 
AA2 7 ILE A 201 ? PRO A 204 ? ILE A 201 PRO A 204 
AA3 1 GLY A 135 ? GLY A 136 ? GLY A 135 GLY A 136 
AA3 2 TYR A 169 ? SER A 170 ? TYR A 169 SER A 170 
AA4 1 ILE A 208 ? TRP A 212 ? ILE A 208 TRP A 212 
AA4 2 SER A 216 ? ILE A 220 ? SER A 216 ILE A 220 
AA5 1 ASN A 257 ? LYS A 258 ? ASN A 257 LYS A 258 
AA5 2 LEU A 271 ? LEU A 272 ? LEU A 271 LEU A 272 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 3   ? N GLN A 3   O TYR A 23  ? O TYR A 23  
AA2 1 2 N LYS A 57  ? N LYS A 57  O LYS A 94  ? O LYS A 94  
AA2 2 3 O PHE A 91  ? O PHE A 91  N VAL A 37  ? N VAL A 37  
AA2 3 4 N TYR A 36  ? N TYR A 36  O VAL A 128 ? O VAL A 128 
AA2 4 5 N ALA A 129 ? N ALA A 129 O MET A 154 ? O MET A 154 
AA2 5 6 N VAL A 157 ? N VAL A 157 O CYS A 178 ? O CYS A 178 
AA2 6 7 N GLY A 181 ? N GLY A 181 O ILE A 201 ? O ILE A 201 
AA3 1 2 N GLY A 135 ? N GLY A 135 O SER A 170 ? O SER A 170 
AA4 1 2 N ILE A 208 ? N ILE A 208 O ILE A 220 ? O ILE A 220 
AA5 1 2 N ASN A 257 ? N ASN A 257 O LEU A 272 ? O LEU A 272 
# 
_pdbx_entry_details.entry_id                   9FTY 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OD1 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   ASP 
_pdbx_validate_close_contact.auth_seq_id_1    165 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    601 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 39  ? ? -156.01 -143.25 
2 1 ASN A 270 ? ? -110.50 74.60   
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     635 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   E 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 -y+1/2,x+1/2,z+3/4  
3 y+1/2,-x+1/2,z+1/4  
4 x+1/2,-y+1/2,-z+1/4 
5 -x+1/2,y+1/2,-z+3/4 
6 -x,-y,z+1/2         
7 y,x,-z              
8 -y,-x,-z+1/2        
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 772 ? 5.99 . 
2 1 O ? A HOH 773 ? 7.05 . 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
NO3 N    N  N N 251 
NO3 O1   O  N N 252 
NO3 O2   O  N N 253 
NO3 O3   O  N N 254 
PHE N    N  N N 255 
PHE CA   C  N S 256 
PHE C    C  N N 257 
PHE O    O  N N 258 
PHE CB   C  N N 259 
PHE CG   C  Y N 260 
PHE CD1  C  Y N 261 
PHE CD2  C  Y N 262 
PHE CE1  C  Y N 263 
PHE CE2  C  Y N 264 
PHE CZ   C  Y N 265 
PHE OXT  O  N N 266 
PHE H    H  N N 267 
PHE H2   H  N N 268 
PHE HA   H  N N 269 
PHE HB2  H  N N 270 
PHE HB3  H  N N 271 
PHE HD1  H  N N 272 
PHE HD2  H  N N 273 
PHE HE1  H  N N 274 
PHE HE2  H  N N 275 
PHE HZ   H  N N 276 
PHE HXT  H  N N 277 
PRO N    N  N N 278 
PRO CA   C  N S 279 
PRO C    C  N N 280 
PRO O    O  N N 281 
PRO CB   C  N N 282 
PRO CG   C  N N 283 
PRO CD   C  N N 284 
PRO OXT  O  N N 285 
PRO H    H  N N 286 
PRO HA   H  N N 287 
PRO HB2  H  N N 288 
PRO HB3  H  N N 289 
PRO HG2  H  N N 290 
PRO HG3  H  N N 291 
PRO HD2  H  N N 292 
PRO HD3  H  N N 293 
PRO HXT  H  N N 294 
SER N    N  N N 295 
SER CA   C  N S 296 
SER C    C  N N 297 
SER O    O  N N 298 
SER CB   C  N N 299 
SER OG   O  N N 300 
SER OXT  O  N N 301 
SER H    H  N N 302 
SER H2   H  N N 303 
SER HA   H  N N 304 
SER HB2  H  N N 305 
SER HB3  H  N N 306 
SER HG   H  N N 307 
SER HXT  H  N N 308 
THR N    N  N N 309 
THR CA   C  N S 310 
THR C    C  N N 311 
THR O    O  N N 312 
THR CB   C  N R 313 
THR OG1  O  N N 314 
THR CG2  C  N N 315 
THR OXT  O  N N 316 
THR H    H  N N 317 
THR H2   H  N N 318 
THR HA   H  N N 319 
THR HB   H  N N 320 
THR HG1  H  N N 321 
THR HG21 H  N N 322 
THR HG22 H  N N 323 
THR HG23 H  N N 324 
THR HXT  H  N N 325 
TRP N    N  N N 326 
TRP CA   C  N S 327 
TRP C    C  N N 328 
TRP O    O  N N 329 
TRP CB   C  N N 330 
TRP CG   C  Y N 331 
TRP CD1  C  Y N 332 
TRP CD2  C  Y N 333 
TRP NE1  N  Y N 334 
TRP CE2  C  Y N 335 
TRP CE3  C  Y N 336 
TRP CZ2  C  Y N 337 
TRP CZ3  C  Y N 338 
TRP CH2  C  Y N 339 
TRP OXT  O  N N 340 
TRP H    H  N N 341 
TRP H2   H  N N 342 
TRP HA   H  N N 343 
TRP HB2  H  N N 344 
TRP HB3  H  N N 345 
TRP HD1  H  N N 346 
TRP HE1  H  N N 347 
TRP HE3  H  N N 348 
TRP HZ2  H  N N 349 
TRP HZ3  H  N N 350 
TRP HH2  H  N N 351 
TRP HXT  H  N N 352 
TYR N    N  N N 353 
TYR CA   C  N S 354 
TYR C    C  N N 355 
TYR O    O  N N 356 
TYR CB   C  N N 357 
TYR CG   C  Y N 358 
TYR CD1  C  Y N 359 
TYR CD2  C  Y N 360 
TYR CE1  C  Y N 361 
TYR CE2  C  Y N 362 
TYR CZ   C  Y N 363 
TYR OH   O  N N 364 
TYR OXT  O  N N 365 
TYR H    H  N N 366 
TYR H2   H  N N 367 
TYR HA   H  N N 368 
TYR HB2  H  N N 369 
TYR HB3  H  N N 370 
TYR HD1  H  N N 371 
TYR HD2  H  N N 372 
TYR HE1  H  N N 373 
TYR HE2  H  N N 374 
TYR HH   H  N N 375 
TYR HXT  H  N N 376 
VAL N    N  N N 377 
VAL CA   C  N S 378 
VAL C    C  N N 379 
VAL O    O  N N 380 
VAL CB   C  N N 381 
VAL CG1  C  N N 382 
VAL CG2  C  N N 383 
VAL OXT  O  N N 384 
VAL H    H  N N 385 
VAL H2   H  N N 386 
VAL HA   H  N N 387 
VAL HB   H  N N 388 
VAL HG11 H  N N 389 
VAL HG12 H  N N 390 
VAL HG13 H  N N 391 
VAL HG21 H  N N 392 
VAL HG22 H  N N 393 
VAL HG23 H  N N 394 
VAL HXT  H  N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
NO3 N   O1   doub N N 237 
NO3 N   O2   sing N N 238 
NO3 N   O3   sing N N 239 
PHE N   CA   sing N N 240 
PHE N   H    sing N N 241 
PHE N   H2   sing N N 242 
PHE CA  C    sing N N 243 
PHE CA  CB   sing N N 244 
PHE CA  HA   sing N N 245 
PHE C   O    doub N N 246 
PHE C   OXT  sing N N 247 
PHE CB  CG   sing N N 248 
PHE CB  HB2  sing N N 249 
PHE CB  HB3  sing N N 250 
PHE CG  CD1  doub Y N 251 
PHE CG  CD2  sing Y N 252 
PHE CD1 CE1  sing Y N 253 
PHE CD1 HD1  sing N N 254 
PHE CD2 CE2  doub Y N 255 
PHE CD2 HD2  sing N N 256 
PHE CE1 CZ   doub Y N 257 
PHE CE1 HE1  sing N N 258 
PHE CE2 CZ   sing Y N 259 
PHE CE2 HE2  sing N N 260 
PHE CZ  HZ   sing N N 261 
PHE OXT HXT  sing N N 262 
PRO N   CA   sing N N 263 
PRO N   CD   sing N N 264 
PRO N   H    sing N N 265 
PRO CA  C    sing N N 266 
PRO CA  CB   sing N N 267 
PRO CA  HA   sing N N 268 
PRO C   O    doub N N 269 
PRO C   OXT  sing N N 270 
PRO CB  CG   sing N N 271 
PRO CB  HB2  sing N N 272 
PRO CB  HB3  sing N N 273 
PRO CG  CD   sing N N 274 
PRO CG  HG2  sing N N 275 
PRO CG  HG3  sing N N 276 
PRO CD  HD2  sing N N 277 
PRO CD  HD3  sing N N 278 
PRO OXT HXT  sing N N 279 
SER N   CA   sing N N 280 
SER N   H    sing N N 281 
SER N   H2   sing N N 282 
SER CA  C    sing N N 283 
SER CA  CB   sing N N 284 
SER CA  HA   sing N N 285 
SER C   O    doub N N 286 
SER C   OXT  sing N N 287 
SER CB  OG   sing N N 288 
SER CB  HB2  sing N N 289 
SER CB  HB3  sing N N 290 
SER OG  HG   sing N N 291 
SER OXT HXT  sing N N 292 
THR N   CA   sing N N 293 
THR N   H    sing N N 294 
THR N   H2   sing N N 295 
THR CA  C    sing N N 296 
THR CA  CB   sing N N 297 
THR CA  HA   sing N N 298 
THR C   O    doub N N 299 
THR C   OXT  sing N N 300 
THR CB  OG1  sing N N 301 
THR CB  CG2  sing N N 302 
THR CB  HB   sing N N 303 
THR OG1 HG1  sing N N 304 
THR CG2 HG21 sing N N 305 
THR CG2 HG22 sing N N 306 
THR CG2 HG23 sing N N 307 
THR OXT HXT  sing N N 308 
TRP N   CA   sing N N 309 
TRP N   H    sing N N 310 
TRP N   H2   sing N N 311 
TRP CA  C    sing N N 312 
TRP CA  CB   sing N N 313 
TRP CA  HA   sing N N 314 
TRP C   O    doub N N 315 
TRP C   OXT  sing N N 316 
TRP CB  CG   sing N N 317 
TRP CB  HB2  sing N N 318 
TRP CB  HB3  sing N N 319 
TRP CG  CD1  doub Y N 320 
TRP CG  CD2  sing Y N 321 
TRP CD1 NE1  sing Y N 322 
TRP CD1 HD1  sing N N 323 
TRP CD2 CE2  doub Y N 324 
TRP CD2 CE3  sing Y N 325 
TRP NE1 CE2  sing Y N 326 
TRP NE1 HE1  sing N N 327 
TRP CE2 CZ2  sing Y N 328 
TRP CE3 CZ3  doub Y N 329 
TRP CE3 HE3  sing N N 330 
TRP CZ2 CH2  doub Y N 331 
TRP CZ2 HZ2  sing N N 332 
TRP CZ3 CH2  sing Y N 333 
TRP CZ3 HZ3  sing N N 334 
TRP CH2 HH2  sing N N 335 
TRP OXT HXT  sing N N 336 
TYR N   CA   sing N N 337 
TYR N   H    sing N N 338 
TYR N   H2   sing N N 339 
TYR CA  C    sing N N 340 
TYR CA  CB   sing N N 341 
TYR CA  HA   sing N N 342 
TYR C   O    doub N N 343 
TYR C   OXT  sing N N 344 
TYR CB  CG   sing N N 345 
TYR CB  HB2  sing N N 346 
TYR CB  HB3  sing N N 347 
TYR CG  CD1  doub Y N 348 
TYR CG  CD2  sing Y N 349 
TYR CD1 CE1  sing Y N 350 
TYR CD1 HD1  sing N N 351 
TYR CD2 CE2  doub Y N 352 
TYR CD2 HD2  sing N N 353 
TYR CE1 CZ   doub Y N 354 
TYR CE1 HE1  sing N N 355 
TYR CE2 CZ   sing Y N 356 
TYR CE2 HE2  sing N N 357 
TYR CZ  OH   sing N N 358 
TYR OH  HH   sing N N 359 
TYR OXT HXT  sing N N 360 
VAL N   CA   sing N N 361 
VAL N   H    sing N N 362 
VAL N   H2   sing N N 363 
VAL CA  C    sing N N 364 
VAL CA  CB   sing N N 365 
VAL CA  HA   sing N N 366 
VAL C   O    doub N N 367 
VAL C   OXT  sing N N 368 
VAL CB  CG1  sing N N 369 
VAL CB  CG2  sing N N 370 
VAL CB  HB   sing N N 371 
VAL CG1 HG11 sing N N 372 
VAL CG1 HG12 sing N N 373 
VAL CG1 HG13 sing N N 374 
VAL CG2 HG21 sing N N 375 
VAL CG2 HG22 sing N N 376 
VAL CG2 HG23 sing N N 377 
VAL OXT HXT  sing N N 378 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5KXU 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'small foils' 
_pdbx_serial_crystallography_sample_delivery.method        'fixed target' 
# 
_space_group.name_H-M_alt     'P 43 21 2' 
_space_group.name_Hall        'P 4nw 2abw' 
_space_group.IT_number        96 
_space_group.crystal_system   tetragonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9FTY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014552 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014552 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009177 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CA ? ? 16.26893 3.65395 ? ? 3.58509  77.28589 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA A 1 1   ? 11.78990 -10.43826 17.66048  1.000 22.07631 ? 1   ALA A N   1 
ATOM   2    C  CA  . ALA A 1 1   ? 12.00682 -9.30137  16.77270  1.000 20.31757 ? 1   ALA A CA  1 
ATOM   3    C  C   . ALA A 1 1   ? 10.93076 -9.24422  15.69717  1.000 20.07379 ? 1   ALA A C   1 
ATOM   4    O  O   . ALA A 1 1   ? 10.29835 -10.25274 15.38089  1.000 19.38859 ? 1   ALA A O   1 
ATOM   5    C  CB  . ALA A 1 1   ? 13.38676 -9.37846  16.13980  1.000 22.20946 ? 1   ALA A CB  1 
ATOM   6    N  N   . ALA A 1 2   ? 10.72991 -8.05681  15.13195  1.000 19.16777 ? 2   ALA A N   1 
ATOM   7    C  CA  . ALA A 1 2   ? 9.71973  -7.84742  14.10283  1.000 19.07486 ? 2   ALA A CA  1 
ATOM   8    C  C   . ALA A 1 2   ? 10.24713 -6.83480  13.10068  1.000 25.49014 ? 2   ALA A C   1 
ATOM   9    O  O   . ALA A 1 2   ? 10.59796 -5.71170  13.47644  1.000 25.30601 ? 2   ALA A O   1 
ATOM   10   C  CB  . ALA A 1 2   ? 8.39979  -7.36495  14.71111  1.000 19.17497 ? 2   ALA A CB  1 
ATOM   11   N  N   . GLN A 1 3   ? 10.31165 -7.23532  11.83361  1.000 18.62694 ? 3   GLN A N   1 
ATOM   12   C  CA  . GLN A 1 3   ? 10.68329 -6.34441  10.74088  1.000 18.15539 ? 3   GLN A CA  1 
ATOM   13   C  C   . GLN A 1 3   ? 9.40633  -5.91342  10.02984  1.000 17.42130 ? 3   GLN A C   1 
ATOM   14   O  O   . GLN A 1 3   ? 8.72069  -6.73869  9.41762   1.000 14.51620 ? 3   GLN A O   1 
ATOM   15   C  CB  . GLN A 1 3   ? 11.64497 -7.02858  9.77156   1.000 16.98032 ? 3   GLN A CB  1 
ATOM   16   C  CG  . GLN A 1 3   ? 11.98902 -6.18281  8.55432   1.000 14.85863 ? 3   GLN A CG  1 
ATOM   17   C  CD  . GLN A 1 3   ? 12.83473 -6.92677  7.54000   1.000 17.99037 ? 3   GLN A CD  1 
ATOM   18   O  OE1 . GLN A 1 3   ? 13.26381 -8.05478  7.77978   1.000 20.98338 ? 3   GLN A OE1 1 
ATOM   19   N  NE2 . GLN A 1 3   ? 13.07625 -6.29735  6.39601   1.000 17.25652 ? 3   GLN A NE2 1 
ATOM   20   N  N   . THR A 1 4   ? 9.08631  -4.62638  10.11647  1.000 16.52503 ? 4   THR A N   1 
ATOM   21   C  CA  . THR A 1 4   ? 7.90934  -4.09599  9.44820   1.000 16.10940 ? 4   THR A CA  1 
ATOM   22   C  C   . THR A 1 4   ? 8.21972  -3.77929  7.98971   1.000 17.05249 ? 4   THR A C   1 
ATOM   23   O  O   . THR A 1 4   ? 9.36272  -3.48902  7.62392   1.000 17.29069 ? 4   THR A O   1 
ATOM   24   C  CB  . THR A 1 4   ? 7.40542  -2.84036  10.15933  1.000 19.94342 ? 4   THR A CB  1 
ATOM   25   O  OG1 . THR A 1 4   ? 8.45650  -1.86826  10.21666  1.000 22.47722 ? 4   THR A OG1 1 
ATOM   26   C  CG2 . THR A 1 4   ? 6.95269  -3.17542  11.57412  1.000 17.71757 ? 4   THR A CG2 1 
ATOM   27   N  N   . ASN A 1 5   ? 7.17826  -3.84047  7.15544   1.000 13.93036 ? 5   ASN A N   1 
ATOM   28   C  CA  . ASN A 1 5   ? 7.29283  -3.59145  5.71556   1.000 15.04332 ? 5   ASN A CA  1 
ATOM   29   C  C   . ASN A 1 5   ? 8.33726  -4.50566  5.07654   1.000 17.45686 ? 5   ASN A C   1 
ATOM   30   O  O   . ASN A 1 5   ? 9.07389  -4.10686  4.17177   1.000 15.03840 ? 5   ASN A O   1 
ATOM   31   C  CB  . ASN A 1 5   ? 7.60414  -2.11962  5.43129   1.000 17.79219 ? 5   ASN A CB  1 
ATOM   32   N  N   . ALA A 1 6   ? 8.39656  -5.74391  5.55140   1.000 16.30577 ? 6   ALA A N   1 
ATOM   33   C  CA  . ALA A 1 6   ? 9.33952  -6.72327  5.04283   1.000 17.03955 ? 6   ALA A CA  1 
ATOM   34   C  C   . ALA A 1 6   ? 8.89868  -7.23373  3.67387   1.000 14.96739 ? 6   ALA A C   1 
ATOM   35   O  O   . ALA A 1 6   ? 7.74213  -7.06111  3.28052   1.000 12.50850 ? 6   ALA A O   1 
ATOM   36   C  CB  . ALA A 1 6   ? 9.46067  -7.88476  6.02559   1.000 12.87234 ? 6   ALA A CB  1 
ATOM   37   N  N   . PRO A 1 7   ? 9.80968  -7.84663  2.91355   1.000 12.50076 ? 7   PRO A N   1 
ATOM   38   C  CA  . PRO A 1 7   ? 9.38910  -8.53817  1.69003   1.000 12.99602 ? 7   PRO A CA  1 
ATOM   39   C  C   . PRO A 1 7   ? 8.32762  -9.58172  2.00459   1.000 13.61820 ? 7   PRO A C   1 
ATOM   40   O  O   . PRO A 1 7   ? 8.31833  -10.18159 3.08206   1.000 14.56952 ? 7   PRO A O   1 
ATOM   41   C  CB  . PRO A 1 7   ? 10.68423 -9.18173  1.18184   1.000 13.07101 ? 7   PRO A CB  1 
ATOM   42   C  CG  . PRO A 1 7   ? 11.76486 -8.30359  1.71716   1.000 14.90751 ? 7   PRO A CG  1 
ATOM   43   C  CD  . PRO A 1 7   ? 11.27683 -7.83106  3.06010   1.000 13.43724 ? 7   PRO A CD  1 
ATOM   44   N  N   . TRP A 1 8   ? 7.41513  -9.78611  1.04932   1.000 13.17311 ? 8   TRP A N   1 
ATOM   45   C  CA  . TRP A 1 8   ? 6.26014  -10.63953 1.31384   1.000 12.55114 ? 8   TRP A CA  1 
ATOM   46   C  C   . TRP A 1 8   ? 6.67575  -12.06456 1.65233   1.000 13.07943 ? 8   TRP A C   1 
ATOM   47   O  O   . TRP A 1 8   ? 6.00558  -12.73126 2.44863   1.000 12.89578 ? 8   TRP A O   1 
ATOM   48   C  CB  . TRP A 1 8   ? 5.30294  -10.63025 0.11726   1.000 13.54384 ? 8   TRP A CB  1 
ATOM   49   C  CG  . TRP A 1 8   ? 5.70879  -11.52493 -1.02123  1.000 14.52731 ? 8   TRP A CG  1 
ATOM   50   C  CD1 . TRP A 1 8   ? 6.37602  -11.15900 -2.15392  1.000 14.16769 ? 8   TRP A CD1 1 
ATOM   51   C  CD2 . TRP A 1 8   ? 5.45849  -12.93330 -1.14129  1.000 14.33362 ? 8   TRP A CD2 1 
ATOM   52   N  NE1 . TRP A 1 8   ? 6.56233  -12.25131 -2.96783  1.000 13.24405 ? 8   TRP A NE1 1 
ATOM   53   C  CE2 . TRP A 1 8   ? 6.00931  -13.35235 -2.36828  1.000 15.46318 ? 8   TRP A CE2 1 
ATOM   54   C  CE3 . TRP A 1 8   ? 4.82788  -13.88018 -0.32699  1.000 14.90722 ? 8   TRP A CE3 1 
ATOM   55   C  CZ2 . TRP A 1 8   ? 5.94696  -14.67566 -2.80104  1.000 14.12623 ? 8   TRP A CZ2 1 
ATOM   56   C  CZ3 . TRP A 1 8   ? 4.77014  -15.19275 -0.75698  1.000 13.82280 ? 8   TRP A CZ3 1 
ATOM   57   C  CH2 . TRP A 1 8   ? 5.32437  -15.57756 -1.98317  1.000 13.36215 ? 8   TRP A CH2 1 
ATOM   58   N  N   . GLY A 1 9   ? 7.77208  -12.54665 1.06454   1.000 11.34567 ? 9   GLY A N   1 
ATOM   59   C  CA  . GLY A 1 9   ? 8.20858  -13.90528 1.34006   1.000 14.45420 ? 9   GLY A CA  1 
ATOM   60   C  C   . GLY A 1 9   ? 8.63950  -14.10400 2.78014   1.000 15.30988 ? 9   GLY A C   1 
ATOM   61   O  O   . GLY A 1 9   ? 8.37080  -15.14774 3.38012   1.000 10.40563 ? 9   GLY A O   1 
ATOM   62   N  N   . LEU A 1 10  ? 9.31581  -13.10643 3.35418   1.000 11.73035 ? 10  LEU A N   1 
ATOM   63   C  CA  . LEU A 1 10  ? 9.70915  -13.19264 4.75650   1.000 12.18474 ? 10  LEU A CA  1 
ATOM   64   C  C   . LEU A 1 10  ? 8.49294  -13.15295 5.67215   1.000 13.30734 ? 10  LEU A C   1 
ATOM   65   O  O   . LEU A 1 10  ? 8.42259  -13.90230 6.65295   1.000 10.31263 ? 10  LEU A O   1 
ATOM   66   C  CB  . LEU A 1 10  ? 10.67720 -12.06114 5.10262   1.000 11.99765 ? 10  LEU A CB  1 
ATOM   67   C  CG  . LEU A 1 10  ? 12.02242 -12.06681 4.37618   1.000 16.80387 ? 10  LEU A CG  1 
ATOM   68   C  CD1 . LEU A 1 10  ? 12.92662 -10.96396 4.90474   1.000 12.30885 ? 10  LEU A CD1 1 
ATOM   69   C  CD2 . LEU A 1 10  ? 12.68878 -13.42478 4.51244   1.000 12.16551 ? 10  LEU A CD2 1 
ATOM   70   N  N   . ALA A 1 11  ? 7.52517  -12.28437 5.36891   1.000 13.36732 ? 11  ALA A N   1 
ATOM   71   C  CA  . ALA A 1 11  ? 6.31051  -12.22494 6.17390   1.000 15.45440 ? 11  ALA A CA  1 
ATOM   72   C  C   . ALA A 1 11  ? 5.49652  -13.50659 6.05659   1.000 15.61238 ? 11  ALA A C   1 
ATOM   73   O  O   . ALA A 1 11  ? 4.78252  -13.87721 6.99553   1.000 18.64935 ? 11  ALA A O   1 
ATOM   74   C  CB  . ALA A 1 11  ? 5.46657  -11.01978 5.76015   1.000 14.92558 ? 11  ALA A CB  1 
ATOM   75   N  N   . ARG A 1 12  ? 5.59773  -14.20082 4.92138   1.000 14.19513 ? 12  ARG A N   1 
ATOM   76   C  CA  . ARG A 1 12  ? 4.80423  -15.40836 4.72178   1.000 16.03965 ? 12  ARG A CA  1 
ATOM   77   C  C   . ARG A 1 12  ? 5.29299  -16.55052 5.60478   1.000 15.51856 ? 12  ARG A C   1 
ATOM   78   O  O   . ARG A 1 12  ? 4.48258  -17.27051 6.20057   1.000 16.06366 ? 12  ARG A O   1 
ATOM   79   C  CB  . ARG A 1 12  ? 4.83727  -15.82231 3.25127   1.000 11.76734 ? 12  ARG A CB  1 
ATOM   80   C  CG  . ARG A 1 12  ? 3.86733  -16.93936 2.91736   1.000 12.47155 ? 12  ARG A CG  1 
ATOM   81   C  CD  . ARG A 1 12  ? 2.43349  -16.48170 3.12759   1.000 13.72500 ? 12  ARG A CD  1 
ATOM   82   N  NE  . ARG A 1 12  ? 1.49152  -17.59410 3.12171   1.000 15.13520 ? 12  ARG A NE  1 
ATOM   83   C  CZ  . ARG A 1 12  ? 1.10987  -18.25682 4.20499   1.000 15.24904 ? 12  ARG A CZ  1 
ATOM   84   N  NH1 . ARG A 1 12  ? 1.57797  -17.95008 5.40385   1.000 16.84680 ? 12  ARG A NH1 1 
ATOM   85   N  NH2 . ARG A 1 12  ? 0.23812  -19.25351 4.08214   1.000 15.52369 ? 12  ARG A NH2 1 
ATOM   86   N  N   . ILE A 1 13  ? 6.61506  -16.73359 5.70525   1.000 12.72638 ? 13  ILE A N   1 
ATOM   87   C  CA  . ILE A 1 13  ? 7.16612  -17.85678 6.46309   1.000 17.05535 ? 13  ILE A CA  1 
ATOM   88   C  C   . ILE A 1 13  ? 7.09410  -17.65388 7.96615   1.000 16.98697 ? 13  ILE A C   1 
ATOM   89   O  O   . ILE A 1 13  ? 7.56458  -18.51718 8.71821   1.000 17.71339 ? 13  ILE A O   1 
ATOM   90   C  CB  . ILE A 1 13  ? 8.63438  -18.13346 6.08366   1.000 17.46249 ? 13  ILE A CB  1 
ATOM   91   C  CG1 . ILE A 1 13  ? 9.51613  -16.94680 6.47417   1.000 18.76257 ? 13  ILE A CG1 1 
ATOM   92   C  CG2 . ILE A 1 13  ? 8.75241  -18.43858 4.59684   1.000 16.06285 ? 13  ILE A CG2 1 
ATOM   93   C  CD1 . ILE A 1 13  ? 10.86433 -17.34838 7.03395   1.000 18.63888 ? 13  ILE A CD1 1 
ATOM   94   N  N   . SER A 1 14  ? 6.53239  -16.53735 8.43192   1.000 16.44844 ? 14  SER A N   1 
ATOM   95   C  CA  . SER A 1 14  ? 6.32364  -16.30223 9.85597   1.000 16.36447 ? 14  SER A CA  1 
ATOM   96   C  C   . SER A 1 14  ? 4.85063  -16.08631 10.17891  1.000 17.33975 ? 14  SER A C   1 
ATOM   97   O  O   . SER A 1 14  ? 4.52353  -15.50797 11.21966  1.000 17.26663 ? 14  SER A O   1 
ATOM   98   C  CB  . SER A 1 14  ? 7.15217  -15.10866 10.33435  1.000 17.22199 ? 14  SER A CB  1 
ATOM   99   O  OG  . SER A 1 14  ? 6.73718  -13.91267 9.69919   1.000 14.68870 ? 14  SER A OG  1 
ATOM   100  N  N   . SER A 1 15  ? 3.95592  -16.53983 9.30432   1.000 16.07565 ? 15  SER A N   1 
ATOM   101  C  CA  . SER A 1 15  ? 2.52554  -16.35334 9.48381   1.000 15.69889 ? 15  SER A CA  1 
ATOM   102  C  C   . SER A 1 15  ? 1.78982  -17.59970 9.01714   1.000 16.66069 ? 15  SER A C   1 
ATOM   103  O  O   . SER A 1 15  ? 2.23997  -18.30272 8.10874   1.000 17.29176 ? 15  SER A O   1 
ATOM   104  C  CB  . SER A 1 15  ? 2.01664  -15.12684 8.71279   1.000 18.49145 ? 15  SER A CB  1 
ATOM   105  O  OG  . SER A 1 15  ? 0.60961  -15.00119 8.82485   1.000 18.43256 ? 15  SER A OG  1 
ATOM   106  N  N   . THR A 1 16  ? 0.65052  -17.86891 9.65333   1.000 15.72574 ? 16  THR A N   1 
ATOM   107  C  CA  . THR A 1 16  ? -0.20562 -18.97137 9.23789   1.000 18.51866 ? 16  THR A CA  1 
ATOM   108  C  C   . THR A 1 16  ? -1.13350 -18.59412 8.09297   1.000 16.95386 ? 16  THR A C   1 
ATOM   109  O  O   . THR A 1 16  ? -1.82839 -19.46976 7.56601   1.000 15.99701 ? 16  THR A O   1 
ATOM   110  C  CB  . THR A 1 16  ? -1.04166 -19.47158 10.41873  1.000 16.40082 ? 16  THR A CB  1 
ATOM   111  O  OG1 . THR A 1 16  ? -1.76661 -18.37604 10.99216  1.000 17.31013 ? 16  THR A OG1 1 
ATOM   112  C  CG2 . THR A 1 16  ? -0.14930 -20.09559 11.47886  1.000 20.04031 ? 16  THR A CG2 1 
ATOM   113  N  N   . SER A 1 17  ? -1.15643 -17.32572 7.69770   1.000 18.29846 ? 17  SER A N   1 
ATOM   114  C  CA  . SER A 1 17  ? -2.05628 -16.82510 6.67365   1.000 18.72694 ? 17  SER A CA  1 
ATOM   115  C  C   . SER A 1 17  ? -1.29932 -15.87634 5.75490   1.000 16.48651 ? 17  SER A C   1 
ATOM   116  O  O   . SER A 1 17  ? -0.34735 -15.21761 6.18736   1.000 15.35463 ? 17  SER A O   1 
ATOM   117  C  CB  . SER A 1 17  ? -3.25822 -16.09443 7.29276   1.000 19.56572 ? 17  SER A CB  1 
ATOM   118  O  OG  . SER A 1 17  ? -2.83805 -14.97195 8.04762   1.000 23.64541 ? 17  SER A OG  1 
ATOM   119  N  N   . PRO A 1 18  ? -1.69432 -15.79688 4.48985   1.000 17.80989 ? 18  PRO A N   1 
ATOM   120  C  CA  . PRO A 1 18  ? -1.06037 -14.84804 3.56972   1.000 14.34401 ? 18  PRO A CA  1 
ATOM   121  C  C   . PRO A 1 18  ? -1.57851 -13.43247 3.79393   1.000 14.38561 ? 18  PRO A C   1 
ATOM   122  O  O   . PRO A 1 18  ? -2.57333 -13.20115 4.48159   1.000 14.77373 ? 18  PRO A O   1 
ATOM   123  C  CB  . PRO A 1 18  ? -1.47084 -15.37666 2.19245   1.000 18.15775 ? 18  PRO A CB  1 
ATOM   124  C  CG  . PRO A 1 18  ? -2.79458 -16.02738 2.43992   1.000 15.12732 ? 18  PRO A CG  1 
ATOM   125  C  CD  . PRO A 1 18  ? -2.69237 -16.64274 3.81203   1.000 18.18698 ? 18  PRO A CD  1 
ATOM   126  N  N   . GLY A 1 19  ? -0.86940 -12.47459 3.20015   1.000 15.12340 ? 19  GLY A N   1 
ATOM   127  C  CA  . GLY A 1 19  ? -1.29405 -11.09087 3.20586   1.000 15.99860 ? 19  GLY A CA  1 
ATOM   128  C  C   . GLY A 1 19  ? -0.66587 -10.20485 4.26078   1.000 17.56511 ? 19  GLY A C   1 
ATOM   129  O  O   . GLY A 1 19  ? -0.90691 -8.99207  4.24361   1.000 17.46032 ? 19  GLY A O   1 
ATOM   130  N  N   . THR A 1 20  ? 0.12354  -10.75830 5.17592   1.000 16.77031 ? 20  THR A N   1 
ATOM   131  C  CA  . THR A 1 20  ? 0.75399  -9.93620  6.19693   1.000 19.36826 ? 20  THR A CA  1 
ATOM   132  C  C   . THR A 1 20  ? 2.02891  -9.29307  5.65149   1.000 20.59791 ? 20  THR A C   1 
ATOM   133  O  O   . THR A 1 20  ? 2.54789  -9.66824  4.59680   1.000 20.98807 ? 20  THR A O   1 
ATOM   134  C  CB  . THR A 1 20  ? 1.06480  -10.76182 7.44596   1.000 17.55724 ? 20  THR A CB  1 
ATOM   135  O  OG1 . THR A 1 20  ? 2.06241  -11.74299 7.13808   1.000 19.14406 ? 20  THR A OG1 1 
ATOM   136  C  CG2 . THR A 1 20  ? -0.19173 -11.46151 7.94073   1.000 19.69785 ? 20  THR A CG2 1 
ATOM   137  N  N   . SER A 1 21  ? 2.54062  -8.30635  6.39329   1.000 21.48107 ? 21  SER A N   1 
ATOM   138  C  CA  . SER A 1 21  ? 3.69445  -7.53302  5.95154   1.000 20.34986 ? 21  SER A CA  1 
ATOM   139  C  C   . SER A 1 21  ? 4.79396  -7.43862  7.00342   1.000 17.23615 ? 21  SER A C   1 
ATOM   140  O  O   . SER A 1 21  ? 5.75957  -6.69227  6.80233   1.000 20.20251 ? 21  SER A O   1 
ATOM   141  C  CB  . SER A 1 21  ? 3.25818  -6.12377  5.53133   1.000 18.70797 ? 21  SER A CB  1 
ATOM   142  O  OG  . SER A 1 21  ? 2.49811  -5.49862  6.55020   1.000 27.05358 ? 21  SER A OG  1 
ATOM   143  N  N   . THR A 1 22  ? 4.68359  -8.17087  8.10793   1.000 17.89296 ? 22  THR A N   1 
ATOM   144  C  CA  . THR A 1 22  ? 5.67669  -8.14446  9.17150   1.000 15.17950 ? 22  THR A CA  1 
ATOM   145  C  C   . THR A 1 22  ? 6.34206  -9.50926  9.28950   1.000 15.28041 ? 22  THR A C   1 
ATOM   146  O  O   . THR A 1 22  ? 5.67166  -10.54526 9.22909   1.000 12.76323 ? 22  THR A O   1 
ATOM   147  C  CB  . THR A 1 22  ? 5.04067  -7.75446  10.51135  1.000 16.92191 ? 22  THR A CB  1 
ATOM   148  O  OG1 . THR A 1 22  ? 4.33486  -6.51570  10.36384  1.000 19.11902 ? 22  THR A OG1 1 
ATOM   149  C  CG2 . THR A 1 22  ? 6.10689  -7.59371  11.58449  1.000 15.96097 ? 22  THR A CG2 1 
ATOM   150  N  N   . TYR A 1 23  ? 7.66326  -9.50356  9.45441   1.000 13.45197 ? 23  TYR A N   1 
ATOM   151  C  CA  . TYR A 1 23  ? 8.44919  -10.72309 9.60756   1.000 14.63590 ? 23  TYR A CA  1 
ATOM   152  C  C   . TYR A 1 23  ? 8.82758  -10.87401 11.07726  1.000 15.92989 ? 23  TYR A C   1 
ATOM   153  O  O   . TYR A 1 23  ? 9.65441  -10.11578 11.59445  1.000 16.71714 ? 23  TYR A O   1 
ATOM   154  C  CB  . TYR A 1 23  ? 9.68839  -10.68311 8.71491   1.000 15.99520 ? 23  TYR A CB  1 
ATOM   155  C  CG  . TYR A 1 23  ? 10.62905 -11.85648 8.89255   1.000 12.48459 ? 23  TYR A CG  1 
ATOM   156  C  CD1 . TYR A 1 23  ? 10.14273 -13.14740 9.05561   1.000 14.64724 ? 23  TYR A CD1 1 
ATOM   157  C  CD2 . TYR A 1 23  ? 12.00606 -11.67364 8.87797   1.000 14.38602 ? 23  TYR A CD2 1 
ATOM   158  C  CE1 . TYR A 1 23  ? 11.00069 -14.22185 9.21221   1.000 14.93668 ? 23  TYR A CE1 1 
ATOM   159  C  CE2 . TYR A 1 23  ? 12.87140 -12.74123 9.03249   1.000 14.63424 ? 23  TYR A CE2 1 
ATOM   160  C  CZ  . TYR A 1 23  ? 12.36354 -14.01272 9.19922   1.000 15.57953 ? 23  TYR A CZ  1 
ATOM   161  O  OH  . TYR A 1 23  ? 13.22255 -15.07730 9.35314   1.000 13.81037 ? 23  TYR A OH  1 
ATOM   162  N  N   . TYR A 1 24  ? 8.21905  -11.84952 11.74526  1.000 15.98266 ? 24  TYR A N   1 
ATOM   163  C  CA  . TYR A 1 24  ? 8.48003  -12.12875 13.15074  1.000 18.88494 ? 24  TYR A CA  1 
ATOM   164  C  C   . TYR A 1 24  ? 9.53107  -13.22600 13.25650  1.000 17.39075 ? 24  TYR A C   1 
ATOM   165  O  O   . TYR A 1 24  ? 9.39477  -14.28155 12.62982  1.000 15.06647 ? 24  TYR A O   1 
ATOM   166  C  CB  . TYR A 1 24  ? 7.19777  -12.55092 13.87083  1.000 18.18319 ? 24  TYR A CB  1 
ATOM   167  C  CG  . TYR A 1 24  ? 6.05211  -11.56928 13.74219  1.000 19.24879 ? 24  TYR A CG  1 
ATOM   168  C  CD1 . TYR A 1 24  ? 5.93160  -10.49367 14.61256  1.000 20.83285 ? 24  TYR A CD1 1 
ATOM   169  C  CD2 . TYR A 1 24  ? 5.08472  -11.72532 12.75668  1.000 19.71765 ? 24  TYR A CD2 1 
ATOM   170  C  CE1 . TYR A 1 24  ? 4.88392  -9.59609  14.50061  1.000 22.31201 ? 24  TYR A CE1 1 
ATOM   171  C  CE2 . TYR A 1 24  ? 4.03369  -10.83319 12.63751  1.000 17.88744 ? 24  TYR A CE2 1 
ATOM   172  C  CZ  . TYR A 1 24  ? 3.93843  -9.77128  13.51166  1.000 21.87075 ? 24  TYR A CZ  1 
ATOM   173  O  OH  . TYR A 1 24  ? 2.89417  -8.88200  13.39567  1.000 28.07852 ? 24  TYR A OH  1 
ATOM   174  N  N   . TYR A 1 25  ? 10.57449 -12.97809 14.04609  1.000 17.63911 ? 25  TYR A N   1 
ATOM   175  C  CA  . TYR A 1 25  ? 11.67250 -13.93040 14.14982  1.000 18.24093 ? 25  TYR A CA  1 
ATOM   176  C  C   . TYR A 1 25  ? 12.39046 -13.73389 15.47691  1.000 18.18053 ? 25  TYR A C   1 
ATOM   177  O  O   . TYR A 1 25  ? 12.34075 -12.65733 16.07941  1.000 16.62661 ? 25  TYR A O   1 
ATOM   178  C  CB  . TYR A 1 25  ? 12.65262 -13.77926 12.97808  1.000 13.59897 ? 25  TYR A CB  1 
ATOM   179  C  CG  . TYR A 1 25  ? 13.37985 -12.45270 12.95281  1.000 15.80892 ? 25  TYR A CG  1 
ATOM   180  C  CD1 . TYR A 1 25  ? 12.78452 -11.32102 12.41017  1.000 18.41631 ? 25  TYR A CD1 1 
ATOM   181  C  CD2 . TYR A 1 25  ? 14.66394 -12.33460 13.46692  1.000 16.44693 ? 25  TYR A CD2 1 
ATOM   182  C  CE1 . TYR A 1 25  ? 13.44681 -10.10774 12.38606  1.000 16.22348 ? 25  TYR A CE1 1 
ATOM   183  C  CE2 . TYR A 1 25  ? 15.33371 -11.12675 13.44731  1.000 17.38773 ? 25  TYR A CE2 1 
ATOM   184  C  CZ  . TYR A 1 25  ? 14.72129 -10.01683 12.90580  1.000 18.90426 ? 25  TYR A CZ  1 
ATOM   185  O  OH  . TYR A 1 25  ? 15.38647 -8.81223  12.88420  1.000 16.11257 ? 25  TYR A OH  1 
ATOM   186  N  N   . ASP A 1 26  ? 13.06430 -14.79423 15.91892  1.000 17.81799 ? 26  ASP A N   1 
ATOM   187  C  CA  . ASP A 1 26  ? 13.85347 -14.74148 17.14018  1.000 17.70398 ? 26  ASP A CA  1 
ATOM   188  C  C   . ASP A 1 26  ? 15.15716 -13.99456 16.89241  1.000 18.32949 ? 26  ASP A C   1 
ATOM   189  O  O   . ASP A 1 26  ? 15.75080 -14.09240 15.81472  1.000 15.59083 ? 26  ASP A O   1 
ATOM   190  C  CB  . ASP A 1 26  ? 14.12720 -16.15778 17.64973  1.000 20.53532 ? 26  ASP A CB  1 
ATOM   191  C  CG  . ASP A 1 26  ? 14.89027 -16.17897 18.95872  1.000 20.20423 ? 26  ASP A CG  1 
ATOM   192  O  OD1 . ASP A 1 26  ? 16.10700 -15.90051 18.94857  1.000 19.34040 ? 26  ASP A OD1 1 
ATOM   193  O  OD2 . ASP A 1 26  ? 14.26797 -16.47049 20.00132  1.000 19.89266 ? 26  ASP A OD2 1 
ATOM   194  N  N   . GLU A 1 27  ? 15.60603 -13.25113 17.90872  1.000 17.21467 ? 27  GLU A N   1 
ATOM   195  C  CA  . GLU A 1 27  ? 16.75396 -12.36284 17.74423  1.000 20.83596 ? 27  GLU A CA  1 
ATOM   196  C  C   . GLU A 1 27  ? 18.06093 -13.10486 17.49327  1.000 17.77467 ? 27  GLU A C   1 
ATOM   197  O  O   . GLU A 1 27  ? 19.03221 -12.47938 17.05402  1.000 16.09762 ? 27  GLU A O   1 
ATOM   198  C  CB  . GLU A 1 27  ? 16.90952 -11.47058 18.97491  1.000 20.29334 ? 27  GLU A CB  1 
ATOM   199  C  CG  . GLU A 1 27  ? 16.02028 -10.23725 18.97758  1.000 27.44357 ? 27  GLU A CG  1 
ATOM   200  C  CD  . GLU A 1 27  ? 14.56741 -10.54031 19.31723  1.000 28.79291 ? 27  GLU A CD  1 
ATOM   201  O  OE1 . GLU A 1 27  ? 14.20838 -11.72917 19.43883  1.000 27.07012 ? 27  GLU A OE1 1 
ATOM   202  O  OE2 . GLU A 1 27  ? 13.78402 -9.58148  19.47974  1.000 30.82328 ? 27  GLU A OE2 1 
ATOM   203  N  N   . SER A 1 28  ? 18.12084 -14.40659 17.78668  1.000 13.89235 ? 28  SER A N   1 
ATOM   204  C  CA  . SER A 1 28  ? 19.33281 -15.16964 17.50340  1.000 16.13934 ? 28  SER A CA  1 
ATOM   205  C  C   . SER A 1 28  ? 19.68615 -15.10320 16.02293  1.000 16.07041 ? 28  SER A C   1 
ATOM   206  O  O   . SER A 1 28  ? 20.86147 -14.96868 15.66355  1.000 20.48899 ? 28  SER A O   1 
ATOM   207  C  CB  . SER A 1 28  ? 19.15395 -16.61678 17.95723  1.000 16.13045 ? 28  SER A CB  1 
ATOM   208  O  OG  . SER A 1 28  ? 17.87813 -17.10085 17.58168  1.000 13.99306 ? 28  SER A OG  1 
ATOM   209  N  N   . ALA A 1 29  ? 18.67841 -15.20352 15.15276  1.000 11.06692 ? 29  ALA A N   1 
ATOM   210  C  CA  . ALA A 1 29  ? 18.81654 -14.90569 13.72510  1.000 13.39860 ? 29  ALA A CA  1 
ATOM   211  C  C   . ALA A 1 29  ? 19.88686 -15.76763 13.05753  1.000 14.16872 ? 29  ALA A C   1 
ATOM   212  O  O   . ALA A 1 29  ? 20.66201 -15.29209 12.22489  1.000 13.55220 ? 29  ALA A O   1 
ATOM   213  C  CB  . ALA A 1 29  ? 19.10270 -13.41891 13.50278  1.000 12.87292 ? 29  ALA A CB  1 
ATOM   214  N  N   . GLY A 1 30  ? 19.92767 -17.04778 13.41904  1.000 12.69723 ? 30  GLY A N   1 
ATOM   215  C  CA  . GLY A 1 30  ? 20.87677 -17.95674 12.80871  1.000 12.82896 ? 30  GLY A CA  1 
ATOM   216  C  C   . GLY A 1 30  ? 22.32648 -17.68150 13.13063  1.000 15.94601 ? 30  GLY A C   1 
ATOM   217  O  O   . GLY A 1 30  ? 23.20992 -18.12666 12.39215  1.000 10.65257 ? 30  GLY A O   1 
ATOM   218  N  N   . GLN A 1 31  ? 22.60028 -16.95226 14.21008  1.000 15.31874 ? 31  GLN A N   1 
ATOM   219  C  CA  . GLN A 1 31  ? 23.97679 -16.67051 14.59389  1.000 15.18018 ? 31  GLN A CA  1 
ATOM   220  C  C   . GLN A 1 31  ? 24.65402 -17.94970 15.06911  1.000 16.99848 ? 31  GLN A C   1 
ATOM   221  O  O   . GLN A 1 31  ? 24.09130 -18.70421 15.86835  1.000 13.09941 ? 31  GLN A O   1 
ATOM   222  C  CB  . GLN A 1 31  ? 24.01864 -15.60630 15.68955  1.000 16.04373 ? 31  GLN A CB  1 
ATOM   223  N  N   . GLY A 1 32  ? 25.86087 -18.19689 14.56915  1.000 15.44977 ? 32  GLY A N   1 
ATOM   224  C  CA  . GLY A 1 32  ? 26.58651 -19.40982 14.86559  1.000 14.53069 ? 32  GLY A CA  1 
ATOM   225  C  C   . GLY A 1 32  ? 26.52776 -20.46489 13.78038  1.000 16.19006 ? 32  GLY A C   1 
ATOM   226  O  O   . GLY A 1 32  ? 27.31947 -21.41477 13.81996  1.000 15.17795 ? 32  GLY A O   1 
ATOM   227  N  N   . SER A 1 33  ? 25.62114 -20.33217 12.81961  1.000 15.96841 ? 33  SER A N   1 
ATOM   228  C  CA  . SER A 1 33  ? 25.51564 -21.26544 11.70888  1.000 14.19661 ? 33  SER A CA  1 
ATOM   229  C  C   . SER A 1 33  ? 26.22773 -20.70880 10.47911  1.000 14.53058 ? 33  SER A C   1 
ATOM   230  O  O   . SER A 1 33  ? 26.59280 -19.53301 10.41401  1.000 12.44016 ? 33  SER A O   1 
ATOM   231  C  CB  . SER A 1 33  ? 24.04673 -21.56318 11.39041  1.000 9.31804  ? 33  SER A CB  1 
ATOM   232  O  OG  . SER A 1 33  ? 23.37413 -20.39877 10.94384  1.000 13.25050 ? 33  SER A OG  1 
ATOM   233  N  N   . CYS A 1 34  ? 26.42422 -21.58020 9.49303   1.000 13.55211 ? 34  CYS A N   1 
ATOM   234  C  CA  . CYS A 1 34  ? 27.07458 -21.22133 8.24144   1.000 14.79093 ? 34  CYS A CA  1 
ATOM   235  C  C   . CYS A 1 34  ? 26.25597 -21.75771 7.07849   1.000 12.26186 ? 34  CYS A C   1 
ATOM   236  O  O   . CYS A 1 34  ? 25.72493 -22.87033 7.14482   1.000 13.63802 ? 34  CYS A O   1 
ATOM   237  C  CB  . CYS A 1 34  ? 28.49784 -21.77990 8.17219   1.000 13.36008 ? 34  CYS A CB  1 
ATOM   238  S  SG  . CYS A 1 34  ? 29.60772 -21.19215 9.46379   1.000 13.01803 ? 34  CYS A SG  1 
ATOM   239  N  N   . VAL A 1 35  ? 26.15547 -20.96642 6.01355   1.000 12.02285 ? 35  VAL A N   1 
ATOM   240  C  CA  . VAL A 1 35  ? 25.41686 -21.35620 4.81830   1.000 10.54476 ? 35  VAL A CA  1 
ATOM   241  C  C   . VAL A 1 35  ? 26.32573 -21.17487 3.61163   1.000 12.58958 ? 35  VAL A C   1 
ATOM   242  O  O   . VAL A 1 35  ? 26.77438 -20.05665 3.33083   1.000 11.79523 ? 35  VAL A O   1 
ATOM   243  C  CB  . VAL A 1 35  ? 24.12207 -20.54573 4.64062   1.000 8.76354  ? 35  VAL A CB  1 
ATOM   244  C  CG1 . VAL A 1 35  ? 23.38784 -21.00257 3.39070   1.000 11.14823 ? 35  VAL A CG1 1 
ATOM   245  C  CG2 . VAL A 1 35  ? 23.23097 -20.68417 5.86535   1.000 8.74392  ? 35  VAL A CG2 1 
ATOM   246  N  N   . TYR A 1 36  ? 26.59854 -22.26891 2.90373   1.000 13.05040 ? 36  TYR A N   1 
ATOM   247  C  CA  . TYR A 1 36  ? 27.31800 -22.19811 1.63958   1.000 11.55811 ? 36  TYR A CA  1 
ATOM   248  C  C   . TYR A 1 36  ? 26.33602 -21.91428 0.50981   1.000 12.79873 ? 36  TYR A C   1 
ATOM   249  O  O   . TYR A 1 36  ? 25.31482 -22.59647 0.37823   1.000 12.26392 ? 36  TYR A O   1 
ATOM   250  C  CB  . TYR A 1 36  ? 28.06646 -23.50337 1.36531   1.000 10.80338 ? 36  TYR A CB  1 
ATOM   251  C  CG  . TYR A 1 36  ? 29.32953 -23.69872 2.17592   1.000 13.37809 ? 36  TYR A CG  1 
ATOM   252  C  CD1 . TYR A 1 36  ? 29.27392 -24.15265 3.48700   1.000 11.23230 ? 36  TYR A CD1 1 
ATOM   253  C  CD2 . TYR A 1 36  ? 30.57943 -23.44931 1.62211   1.000 12.75113 ? 36  TYR A CD2 1 
ATOM   254  C  CE1 . TYR A 1 36  ? 30.42649 -24.34038 4.22900   1.000 9.46115  ? 36  TYR A CE1 1 
ATOM   255  C  CE2 . TYR A 1 36  ? 31.73874 -23.63490 2.35683   1.000 15.75280 ? 36  TYR A CE2 1 
ATOM   256  C  CZ  . TYR A 1 36  ? 31.65538 -24.08076 3.65980   1.000 13.95202 ? 36  TYR A CZ  1 
ATOM   257  O  OH  . TYR A 1 36  ? 32.80239 -24.26805 4.39749   1.000 14.51038 ? 36  TYR A OH  1 
ATOM   258  N  N   . VAL A 1 37  ? 26.64076 -20.90700 -0.30055  1.000 11.75457 ? 37  VAL A N   1 
ATOM   259  C  CA  . VAL A 1 37  ? 25.83205 -20.55758 -1.46240  1.000 10.86089 ? 37  VAL A CA  1 
ATOM   260  C  C   . VAL A 1 37  ? 26.61709 -20.98764 -2.69388  1.000 12.70092 ? 37  VAL A C   1 
ATOM   261  O  O   . VAL A 1 37  ? 27.58086 -20.32746 -3.09680  1.000 13.01529 ? 37  VAL A O   1 
ATOM   262  C  CB  . VAL A 1 37  ? 25.48850 -19.06522 -1.50573  1.000 13.81482 ? 37  VAL A CB  1 
ATOM   263  C  CG1 . VAL A 1 37  ? 24.70247 -18.74751 -2.76970  1.000 14.65298 ? 37  VAL A CG1 1 
ATOM   264  C  CG2 . VAL A 1 37  ? 24.69487 -18.66884 -0.27345  1.000 11.08931 ? 37  VAL A CG2 1 
ATOM   265  N  N   . ILE A 1 38  ? 26.20175 -22.09857 -3.29553  1.000 11.64211 ? 38  ILE A N   1 
ATOM   266  C  CA  . ILE A 1 38  ? 26.87432 -22.66556 -4.45794  1.000 11.67490 ? 38  ILE A CA  1 
ATOM   267  C  C   . ILE A 1 38  ? 26.16809 -22.11451 -5.69275  1.000 12.29494 ? 38  ILE A C   1 
ATOM   268  O  O   . ILE A 1 38  ? 25.13311 -22.63158 -6.11734  1.000 9.97192  ? 38  ILE A O   1 
ATOM   269  C  CB  . ILE A 1 38  ? 26.85774 -24.19337 -4.42252  1.000 12.41580 ? 38  ILE A CB  1 
ATOM   270  C  CG1 . ILE A 1 38  ? 27.35371 -24.68804 -3.06299  1.000 11.04083 ? 38  ILE A CG1 1 
ATOM   271  C  CG2 . ILE A 1 38  ? 27.71457 -24.76105 -5.53727  1.000 14.25594 ? 38  ILE A CG2 1 
ATOM   272  C  CD1 . ILE A 1 38  ? 27.25767 -26.18223 -2.88621  1.000 15.24236 ? 38  ILE A CD1 1 
ATOM   273  N  N   . ASP A 1 39  ? 26.73513 -21.06084 -6.27848  1.000 11.04173 ? 39  ASP A N   1 
ATOM   274  C  CA  . ASP A 1 39  ? 26.05078 -20.34391 -7.34629  1.000 12.40064 ? 39  ASP A CA  1 
ATOM   275  C  C   . ASP A 1 39  ? 27.05165 -19.60917 -8.23425  1.000 14.76627 ? 39  ASP A C   1 
ATOM   276  O  O   . ASP A 1 39  ? 28.14763 -20.11789 -8.49505  1.000 14.01284 ? 39  ASP A O   1 
ATOM   277  C  CB  . ASP A 1 39  ? 25.02888 -19.37874 -6.73736  1.000 10.08928 ? 39  ASP A CB  1 
ATOM   278  C  CG  . ASP A 1 39  ? 23.85781 -19.10747 -7.65596  1.000 12.93240 ? 39  ASP A CG  1 
ATOM   279  O  OD1 . ASP A 1 39  ? 24.08733 -18.66280 -8.79953  1.000 13.12176 ? 39  ASP A OD1 1 
ATOM   280  O  OD2 . ASP A 1 39  ? 22.70518 -19.34395 -7.23567  1.000 13.26005 ? 39  ASP A OD2 1 
ATOM   281  N  N   . THR A 1 40  ? 26.68475 -18.41743 -8.70617  1.000 11.99225 ? 40  THR A N   1 
ATOM   282  C  CA  . THR A 1 40  ? 27.55929 -17.60473 -9.54437  1.000 12.68583 ? 40  THR A CA  1 
ATOM   283  C  C   . THR A 1 40  ? 28.53520 -16.75730 -8.74053  1.000 11.98183 ? 40  THR A C   1 
ATOM   284  O  O   . THR A 1 40  ? 29.31675 -16.00959 -9.33795  1.000 11.60952 ? 40  THR A O   1 
ATOM   285  C  CB  . THR A 1 40  ? 26.73209 -16.68012 -10.44394 1.000 12.99155 ? 40  THR A CB  1 
ATOM   286  O  OG1 . THR A 1 40  ? 25.98250 -15.76995 -9.62899  1.000 11.70106 ? 40  THR A OG1 1 
ATOM   287  C  CG2 . THR A 1 40  ? 25.77757 -17.48179 -11.31255 1.000 10.69448 ? 40  THR A CG2 1 
ATOM   288  N  N   . GLY A 1 41  ? 28.50936 -16.84871 -7.41935  1.000 11.45394 ? 41  GLY A N   1 
ATOM   289  C  CA  . GLY A 1 41  ? 29.32107 -16.00988 -6.56096  1.000 11.46271 ? 41  GLY A CA  1 
ATOM   290  C  C   . GLY A 1 41  ? 28.46094 -15.07156 -5.73358  1.000 10.04462 ? 41  GLY A C   1 
ATOM   291  O  O   . GLY A 1 41  ? 27.23627 -15.03010 -5.85162  1.000 10.09696 ? 41  GLY A O   1 
ATOM   292  N  N   . ILE A 1 42  ? 29.13622 -14.31360 -4.87536  1.000 10.60402 ? 42  ILE A N   1 
ATOM   293  C  CA  . ILE A 1 42  ? 28.48796 -13.34664 -3.99773  1.000 8.79859  ? 42  ILE A CA  1 
ATOM   294  C  C   . ILE A 1 42  ? 29.26982 -12.04325 -4.05636  1.000 14.16183 ? 42  ILE A C   1 
ATOM   295  O  O   . ILE A 1 42  ? 30.50231 -12.04964 -3.96201  1.000 12.81671 ? 42  ILE A O   1 
ATOM   296  C  CB  . ILE A 1 42  ? 28.40138 -13.85057 -2.54249  1.000 12.62197 ? 42  ILE A CB  1 
ATOM   297  C  CG1 . ILE A 1 42  ? 27.69704 -15.20650 -2.47244  1.000 10.14639 ? 42  ILE A CG1 1 
ATOM   298  C  CG2 . ILE A 1 42  ? 27.67113 -12.84197 -1.66992  1.000 12.06080 ? 42  ILE A CG2 1 
ATOM   299  C  CD1 . ILE A 1 42  ? 27.65522 -15.79518 -1.07785  1.000 10.89431 ? 42  ILE A CD1 1 
ATOM   300  N  N   . GLU A 1 43  ? 28.55669 -10.92820 -4.21881  1.000 10.27230 ? 43  GLU A N   1 
ATOM   301  C  CA  . GLU A 1 43  ? 29.16073 -9.60549  -4.07271  1.000 14.16542 ? 43  GLU A CA  1 
ATOM   302  C  C   . GLU A 1 43  ? 29.28454 -9.33144  -2.57608  1.000 15.37443 ? 43  GLU A C   1 
ATOM   303  O  O   . GLU A 1 43  ? 28.43736 -8.69202  -1.94753  1.000 14.78966 ? 43  GLU A O   1 
ATOM   304  C  CB  . GLU A 1 43  ? 28.33518 -8.54420  -4.79029  1.000 11.77891 ? 43  GLU A CB  1 
ATOM   305  C  CG  . GLU A 1 43  ? 28.91697 -7.13810  -4.70555  1.000 15.65390 ? 43  GLU A CG  1 
ATOM   306  C  CD  . GLU A 1 43  ? 28.24686 -6.16706  -5.65914  1.000 17.63546 ? 43  GLU A CD  1 
ATOM   307  O  OE1 . GLU A 1 43  ? 28.44758 -6.30097  -6.88472  1.000 15.04518 ? 43  GLU A OE1 1 
ATOM   308  O  OE2 . GLU A 1 43  ? 27.51474 -5.27318  -5.18443  1.000 15.26506 ? 43  GLU A OE2 1 
ATOM   309  N  N   . ALA A 1 44  ? 30.37012 -9.84960  -1.99507  1.000 15.21851 ? 44  ALA A N   1 
ATOM   310  C  CA  . ALA A 1 44  ? 30.54347 -9.80681  -0.54756  1.000 16.37685 ? 44  ALA A CA  1 
ATOM   311  C  C   . ALA A 1 44  ? 30.65771 -8.38533  -0.01440  1.000 16.88546 ? 44  ALA A C   1 
ATOM   312  O  O   . ALA A 1 44  ? 30.37285 -8.15383  1.16638   1.000 16.60997 ? 44  ALA A O   1 
ATOM   313  C  CB  . ALA A 1 44  ? 31.77512 -10.61613 -0.14228  1.000 18.01642 ? 44  ALA A CB  1 
ATOM   314  N  N   . SER A 1 45  ? 31.06045 -7.43020  -0.85131  1.000 17.23507 ? 45  SER A N   1 
ATOM   315  C  CA  . SER A 1 45  ? 31.18791 -6.04208  -0.42732  1.000 16.37613 ? 45  SER A CA  1 
ATOM   316  C  C   . SER A 1 45  ? 29.84749 -5.32899  -0.31329  1.000 15.16576 ? 45  SER A C   1 
ATOM   317  O  O   . SER A 1 45  ? 29.82435 -4.15858  0.08189   1.000 17.05390 ? 45  SER A O   1 
ATOM   318  C  CB  . SER A 1 45  ? 32.09302 -5.27803  -1.39831  1.000 12.80632 ? 45  SER A CB  1 
ATOM   319  O  OG  . SER A 1 45  ? 31.51072 -5.20369  -2.68754  1.000 20.05149 ? 45  SER A OG  1 
ATOM   320  N  N   . HIS A 1 46  ? 28.74639 -5.99490  -0.64926  1.000 14.27529 ? 46  HIS A N   1 
ATOM   321  C  CA  . HIS A 1 46  ? 27.43517 -5.36923  -0.56003  1.000 13.06854 ? 46  HIS A CA  1 
ATOM   322  C  C   . HIS A 1 46  ? 27.14794 -4.98580  0.88902   1.000 14.67679 ? 46  HIS A C   1 
ATOM   323  O  O   . HIS A 1 46  ? 27.30555 -5.82249  1.78958   1.000 17.81494 ? 46  HIS A O   1 
ATOM   324  C  CB  . HIS A 1 46  ? 26.35313 -6.31408  -1.08370  1.000 12.77685 ? 46  HIS A CB  1 
ATOM   325  C  CG  . HIS A 1 46  ? 25.09110 -5.62310  -1.50124  1.000 12.64992 ? 46  HIS A CG  1 
ATOM   326  N  ND1 . HIS A 1 46  ? 24.31690 -4.89052  -0.62735  1.000 12.42885 ? 46  HIS A ND1 1 
ATOM   327  C  CD2 . HIS A 1 46  ? 24.46347 -5.56295  -2.69991  1.000 12.65484 ? 46  HIS A CD2 1 
ATOM   328  C  CE1 . HIS A 1 46  ? 23.27086 -4.40338  -1.27074  1.000 12.45901 ? 46  HIS A CE1 1 
ATOM   329  N  NE2 . HIS A 1 46  ? 23.33555 -4.79747  -2.52976  1.000 12.40576 ? 46  HIS A NE2 1 
ATOM   330  N  N   . PRO A 1 47  ? 26.74322 -3.74171  1.15666   1.000 14.51006 ? 47  PRO A N   1 
ATOM   331  C  CA  . PRO A 1 47  ? 26.51473 -3.32457  2.55132   1.000 17.52617 ? 47  PRO A CA  1 
ATOM   332  C  C   . PRO A 1 47  ? 25.46045 -4.14553  3.27243   1.000 15.94058 ? 47  PRO A C   1 
ATOM   333  O  O   . PRO A 1 47  ? 25.49797 -4.23716  4.50596   1.000 14.78544 ? 47  PRO A O   1 
ATOM   334  C  CB  . PRO A 1 47  ? 26.08313 -1.85799  2.40624   1.000 14.86692 ? 47  PRO A CB  1 
ATOM   335  C  CG  . PRO A 1 47  ? 26.66091 -1.42034  1.09609   1.000 14.98103 ? 47  PRO A CG  1 
ATOM   336  C  CD  . PRO A 1 47  ? 26.59604 -2.62529  0.20815   1.000 13.95175 ? 47  PRO A CD  1 
ATOM   337  N  N   . GLU A 1 48  ? 24.52210 -4.75011  2.54093   1.000 14.45292 ? 48  GLU A N   1 
ATOM   338  C  CA  . GLU A 1 48  ? 23.48145 -5.55273  3.17116   1.000 13.40154 ? 48  GLU A CA  1 
ATOM   339  C  C   . GLU A 1 48  ? 24.02615 -6.81369  3.83219   1.000 15.08229 ? 48  GLU A C   1 
ATOM   340  O  O   . GLU A 1 48  ? 23.31699 -7.42807  4.63585   1.000 13.19595 ? 48  GLU A O   1 
ATOM   341  C  CB  . GLU A 1 48  ? 22.41376 -5.92335  2.14014   1.000 16.12904 ? 48  GLU A CB  1 
ATOM   342  C  CG  . GLU A 1 48  ? 21.41500 -4.81317  1.85768   1.000 13.61790 ? 48  GLU A CG  1 
ATOM   343  C  CD  . GLU A 1 48  ? 20.42076 -4.63185  2.98762   1.000 18.98792 ? 48  GLU A CD  1 
ATOM   344  O  OE1 . GLU A 1 48  ? 20.13814 -5.62416  3.69126   1.000 18.58418 ? 48  GLU A OE1 1 
ATOM   345  O  OE2 . GLU A 1 48  ? 19.92445 -3.50107  3.17637   1.000 16.12088 ? 48  GLU A OE2 1 
ATOM   346  N  N   . PHE A 1 49  ? 25.25803 -7.21570  3.51855   1.000 15.82301 ? 49  PHE A N   1 
ATOM   347  C  CA  . PHE A 1 49  ? 25.84275 -8.40204  4.12989   1.000 14.78582 ? 49  PHE A CA  1 
ATOM   348  C  C   . PHE A 1 49  ? 26.62007 -8.09566  5.40304   1.000 13.82722 ? 49  PHE A C   1 
ATOM   349  O  O   . PHE A 1 49  ? 26.93209 -9.02462  6.15762   1.000 11.66401 ? 49  PHE A O   1 
ATOM   350  C  CB  . PHE A 1 49  ? 26.75299 -9.11493  3.12684   1.000 14.73887 ? 49  PHE A CB  1 
ATOM   351  C  CG  . PHE A 1 49  ? 26.00990 -9.75657  1.99223   1.000 12.02741 ? 49  PHE A CG  1 
ATOM   352  C  CD1 . PHE A 1 49  ? 24.90252 -10.55149 2.23650   1.000 11.30716 ? 49  PHE A CD1 1 
ATOM   353  C  CD2 . PHE A 1 49  ? 26.40484 -9.54992  0.68141   1.000 13.29408 ? 49  PHE A CD2 1 
ATOM   354  C  CE1 . PHE A 1 49  ? 24.21089 -11.14029 1.19622   1.000 13.67899 ? 49  PHE A CE1 1 
ATOM   355  C  CE2 . PHE A 1 49  ? 25.71610 -10.13432 -0.36369  1.000 13.80699 ? 49  PHE A CE2 1 
ATOM   356  C  CZ  . PHE A 1 49  ? 24.61829 -10.93079 -0.10581  1.000 9.37734  ? 49  PHE A CZ  1 
ATOM   357  N  N   . GLU A 1 50  ? 26.94137 -6.82215  5.64998   1.000 14.87364 ? 50  GLU A N   1 
ATOM   358  C  CA  . GLU A 1 50  ? 27.55838 -6.36872  6.89941   1.000 13.78526 ? 50  GLU A CA  1 
ATOM   359  C  C   . GLU A 1 50  ? 28.88618 -7.06877  7.18133   1.000 15.70364 ? 50  GLU A C   1 
ATOM   360  O  O   . GLU A 1 50  ? 29.30414 -7.18354  8.33640   1.000 12.41933 ? 50  GLU A O   1 
ATOM   361  C  CB  . GLU A 1 50  ? 26.60319 -6.55035  8.08266   1.000 15.29491 ? 50  GLU A CB  1 
ATOM   362  C  CG  . GLU A 1 50  ? 25.29872 -5.78131  7.95544   1.000 12.66271 ? 50  GLU A CG  1 
ATOM   363  C  CD  . GLU A 1 50  ? 24.28276 -6.18685  9.00536   1.000 15.50655 ? 50  GLU A CD  1 
ATOM   364  O  OE1 . GLU A 1 50  ? 24.17702 -7.39714  9.29564   1.000 15.31335 ? 50  GLU A OE1 1 
ATOM   365  O  OE2 . GLU A 1 50  ? 23.59463 -5.29601  9.54569   1.000 17.89528 ? 50  GLU A OE2 1 
ATOM   366  N  N   . GLY A 1 51  ? 29.56764 -7.53303  6.13695   1.000 13.47226 ? 51  GLY A N   1 
ATOM   367  C  CA  . GLY A 1 51  ? 30.82277 -8.22753  6.32082   1.000 13.51751 ? 51  GLY A CA  1 
ATOM   368  C  C   . GLY A 1 51  ? 30.70357 -9.66809  6.75926   1.000 15.93556 ? 51  GLY A C   1 
ATOM   369  O  O   . GLY A 1 51  ? 31.71420 -10.26517 7.14916   1.000 15.50178 ? 51  GLY A O   1 
ATOM   370  N  N   . ARG A 1 52  ? 29.50703 -10.24793 6.71176   1.000 12.31638 ? 52  ARG A N   1 
ATOM   371  C  CA  . ARG A 1 52  ? 29.30369 -11.64197 7.07743   1.000 12.68135 ? 52  ARG A CA  1 
ATOM   372  C  C   . ARG A 1 52  ? 29.40105 -12.58703 5.88629   1.000 15.37404 ? 52  ARG A C   1 
ATOM   373  O  O   . ARG A 1 52  ? 29.14475 -13.78536 6.04100   1.000 15.52428 ? 52  ARG A O   1 
ATOM   374  C  CB  . ARG A 1 52  ? 27.94603 -11.81446 7.76575   1.000 15.57915 ? 52  ARG A CB  1 
ATOM   375  C  CG  . ARG A 1 52  ? 27.89126 -11.24988 9.17600   1.000 18.17930 ? 52  ARG A CG  1 
ATOM   376  C  CD  . ARG A 1 52  ? 26.50367 -11.39329 9.78602   1.000 18.66560 ? 52  ARG A CD  1 
ATOM   377  N  NE  . ARG A 1 52  ? 25.53805 -10.49045 9.16945   1.000 15.44760 ? 52  ARG A NE  1 
ATOM   378  C  CZ  . ARG A 1 52  ? 24.66146 -10.84392 8.23907   1.000 15.80404 ? 52  ARG A CZ  1 
ATOM   379  N  NH1 . ARG A 1 52  ? 24.58420 -12.08920 7.79814   1.000 12.50171 ? 52  ARG A NH1 1 
ATOM   380  N  NH2 . ARG A 1 52  ? 23.83898 -9.92482  7.74090   1.000 12.42463 ? 52  ARG A NH2 1 
ATOM   381  N  N   . ALA A 1 53  ? 29.76692 -12.08320 4.71103   1.000 12.28526 ? 53  ALA A N   1 
ATOM   382  C  CA  . ALA A 1 53  ? 29.88165 -12.89691 3.51159   1.000 16.54172 ? 53  ALA A CA  1 
ATOM   383  C  C   . ALA A 1 53  ? 31.30755 -12.84617 2.98106   1.000 15.32352 ? 53  ALA A C   1 
ATOM   384  O  O   . ALA A 1 53  ? 31.99029 -11.82250 3.08398   1.000 15.67156 ? 53  ALA A O   1 
ATOM   385  C  CB  . ALA A 1 53  ? 28.90511 -12.43067 2.42487   1.000 11.98986 ? 53  ALA A CB  1 
ATOM   386  N  N   . GLN A 1 54  ? 31.75398 -13.96490 2.41457   1.000 12.31196 ? 54  GLN A N   1 
ATOM   387  C  CA  . GLN A 1 54  ? 33.08110 -14.03021 1.82101   1.000 16.98072 ? 54  GLN A CA  1 
ATOM   388  C  C   . GLN A 1 54  ? 33.11681 -15.16812 0.81171   1.000 15.81165 ? 54  GLN A C   1 
ATOM   389  O  O   . GLN A 1 54  ? 32.41465 -16.17287 0.96024   1.000 15.09624 ? 54  GLN A O   1 
ATOM   390  C  CB  . GLN A 1 54  ? 34.17120 -14.21606 2.88642   1.000 24.34980 ? 54  GLN A CB  1 
ATOM   391  C  CG  . GLN A 1 54  ? 34.72236 -15.63107 2.99812   1.000 21.06904 ? 54  GLN A CG  1 
ATOM   392  C  CD  . GLN A 1 54  ? 35.85961 -15.73911 3.99526   1.000 31.41808 ? 54  GLN A CD  1 
ATOM   393  O  OE1 . GLN A 1 54  ? 35.77805 -15.21743 5.10702   1.000 37.48970 ? 54  GLN A OE1 1 
ATOM   394  N  NE2 . GLN A 1 54  ? 36.93265 -16.41321 3.59760   1.000 28.16882 ? 54  GLN A NE2 1 
ATOM   395  N  N   . MET A 1 55  ? 33.93186 -14.98728 -0.22382  1.000 13.36023 ? 55  MET A N   1 
ATOM   396  C  CA  . MET A 1 55  ? 34.14983 -16.01857 -1.22591  1.000 13.85753 ? 55  MET A CA  1 
ATOM   397  C  C   . MET A 1 55  ? 35.28403 -16.93279 -0.78653  1.000 17.17733 ? 55  MET A C   1 
ATOM   398  O  O   . MET A 1 55  ? 36.33267 -16.46727 -0.33178  1.000 17.88298 ? 55  MET A O   1 
ATOM   399  C  CB  . MET A 1 55  ? 34.47409 -15.39707 -2.58446  1.000 13.80736 ? 55  MET A CB  1 
ATOM   400  C  CG  . MET A 1 55  ? 33.31729 -14.64756 -3.22224  1.000 16.64378 ? 55  MET A CG  1 
ATOM   401  S  SD  . MET A 1 55  ? 31.99476 -15.73881 -3.78179  1.000 14.64168 ? 55  MET A SD  1 
ATOM   402  C  CE  . MET A 1 55  ? 32.85587 -16.72207 -5.00671  1.000 11.85662 ? 55  MET A CE  1 
ATOM   403  N  N   . VAL A 1 56  ? 35.06538 -18.23784 -0.92058  1.000 11.89299 ? 56  VAL A N   1 
ATOM   404  C  CA  . VAL A 1 56  ? 36.05971 -19.22155 -0.51627  1.000 16.03442 ? 56  VAL A CA  1 
ATOM   405  C  C   . VAL A 1 56  ? 36.55862 -20.07690 -1.67192  1.000 14.47737 ? 56  VAL A C   1 
ATOM   406  O  O   . VAL A 1 56  ? 37.62730 -20.69703 -1.54329  1.000 12.00157 ? 56  VAL A O   1 
ATOM   407  C  CB  . VAL A 1 56  ? 35.51868 -20.12227 0.61417   1.000 15.09291 ? 56  VAL A CB  1 
ATOM   408  C  CG1 . VAL A 1 56  ? 35.07204 -19.27576 1.79695   1.000 16.78166 ? 56  VAL A CG1 1 
ATOM   409  C  CG2 . VAL A 1 56  ? 34.37522 -20.98629 0.10608   1.000 11.32659 ? 56  VAL A CG2 1 
ATOM   410  N  N   . LYS A 1 57  ? 35.84973 -20.13382 -2.79794  1.000 13.76599 ? 57  LYS A N   1 
ATOM   411  C  CA  . LYS A 1 57  ? 36.25945 -20.99175 -3.89972  1.000 12.77564 ? 57  LYS A CA  1 
ATOM   412  C  C   . LYS A 1 57  ? 35.60274 -20.51945 -5.18765  1.000 15.64059 ? 57  LYS A C   1 
ATOM   413  O  O   . LYS A 1 57  ? 34.41404 -20.18942 -5.20256  1.000 14.15992 ? 57  LYS A O   1 
ATOM   414  C  CB  . LYS A 1 57  ? 35.88852 -22.45451 -3.62825  1.000 15.45154 ? 57  LYS A CB  1 
ATOM   415  C  CG  . LYS A 1 57  ? 36.28611 -23.42197 -4.73056  1.000 12.58271 ? 57  LYS A CG  1 
ATOM   416  C  CD  . LYS A 1 57  ? 37.79565 -23.55957 -4.83281  1.000 16.77002 ? 57  LYS A CD  1 
ATOM   417  C  CE  . LYS A 1 57  ? 38.18238 -24.57354 -5.89751  1.000 18.68370 ? 57  LYS A CE  1 
ATOM   418  N  NZ  . LYS A 1 57  ? 39.65553 -24.78221 -5.96038  1.000 23.82007 ? 57  LYS A NZ  1 
ATOM   419  N  N   . THR A 1 58  ? 36.38614 -20.49390 -6.26139  1.000 12.68110 ? 58  THR A N   1 
ATOM   420  C  CA  . THR A 1 58  ? 35.87493 -20.25345 -7.59992  1.000 13.48689 ? 58  THR A CA  1 
ATOM   421  C  C   . THR A 1 58  ? 36.52197 -21.24324 -8.55619  1.000 16.16308 ? 58  THR A C   1 
ATOM   422  O  O   . THR A 1 58  ? 37.67733 -21.63925 -8.37986  1.000 17.23718 ? 58  THR A O   1 
ATOM   423  C  CB  . THR A 1 58  ? 36.13478 -18.81011 -8.07276  1.000 16.17813 ? 58  THR A CB  1 
ATOM   424  O  OG1 . THR A 1 58  ? 35.59343 -18.63080 -9.38741  1.000 19.11981 ? 58  THR A OG1 1 
ATOM   425  C  CG2 . THR A 1 58  ? 37.62681 -18.50364 -8.09797  1.000 17.50785 ? 58  THR A CG2 1 
ATOM   426  N  N   . TYR A 1 59  ? 35.75379 -21.66213 -9.55962  1.000 15.18027 ? 59  TYR A N   1 
ATOM   427  C  CA  . TYR A 1 59  ? 36.24708 -22.55950 -10.59451 1.000 18.37700 ? 59  TYR A CA  1 
ATOM   428  C  C   . TYR A 1 59  ? 36.42067 -21.84332 -11.92710 1.000 18.36840 ? 59  TYR A C   1 
ATOM   429  O  O   . TYR A 1 59  ? 36.43813 -22.48707 -12.98156 1.000 20.53857 ? 59  TYR A O   1 
ATOM   430  C  CB  . TYR A 1 59  ? 35.31409 -23.76060 -10.74200 1.000 17.24192 ? 59  TYR A CB  1 
ATOM   431  C  CG  . TYR A 1 59  ? 35.31655 -24.68363 -9.54186  1.000 18.52487 ? 59  TYR A CG  1 
ATOM   432  C  CD1 . TYR A 1 59  ? 36.22161 -25.73361 -9.45242  1.000 17.25332 ? 59  TYR A CD1 1 
ATOM   433  C  CD2 . TYR A 1 59  ? 34.41619 -24.50493 -8.49829  1.000 17.93335 ? 59  TYR A CD2 1 
ATOM   434  C  CE1 . TYR A 1 59  ? 36.23043 -26.58087 -8.35940  1.000 15.25815 ? 59  TYR A CE1 1 
ATOM   435  C  CE2 . TYR A 1 59  ? 34.41726 -25.34850 -7.39968  1.000 17.08848 ? 59  TYR A CE2 1 
ATOM   436  C  CZ  . TYR A 1 59  ? 35.32684 -26.38461 -7.33607  1.000 14.95408 ? 59  TYR A CZ  1 
ATOM   437  O  OH  . TYR A 1 59  ? 35.33409 -27.22730 -6.24727  1.000 16.54828 ? 59  TYR A OH  1 
ATOM   438  N  N   . TYR A 1 60  ? 36.55097 -20.52039 -11.89532 1.000 18.99503 ? 60  TYR A N   1 
ATOM   439  C  CA  . TYR A 1 60  ? 36.71196 -19.71947 -13.09723 1.000 17.93957 ? 60  TYR A CA  1 
ATOM   440  C  C   . TYR A 1 60  ? 37.83432 -18.71616 -12.84872 1.000 19.85317 ? 60  TYR A C   1 
ATOM   441  O  O   . TYR A 1 60  ? 38.56431 -18.80081 -11.85539 1.000 19.01626 ? 60  TYR A O   1 
ATOM   442  C  CB  . TYR A 1 60  ? 35.37977 -19.05766 -13.47762 1.000 20.79511 ? 60  TYR A CB  1 
ATOM   443  C  CG  . TYR A 1 60  ? 34.27209 -20.05463 -13.75381 1.000 21.67285 ? 60  TYR A CG  1 
ATOM   444  C  CD1 . TYR A 1 60  ? 33.44350 -20.50668 -12.73289 1.000 17.35371 ? 60  TYR A CD1 1 
ATOM   445  C  CD2 . TYR A 1 60  ? 34.06196 -20.55064 -15.03386 1.000 18.15928 ? 60  TYR A CD2 1 
ATOM   446  C  CE1 . TYR A 1 60  ? 32.43411 -21.42237 -12.98118 1.000 19.18914 ? 60  TYR A CE1 1 
ATOM   447  C  CE2 . TYR A 1 60  ? 33.05428 -21.46522 -15.29183 1.000 26.62606 ? 60  TYR A CE2 1 
ATOM   448  C  CZ  . TYR A 1 60  ? 32.24353 -21.89734 -14.26188 1.000 18.45623 ? 60  TYR A CZ  1 
ATOM   449  O  OH  . TYR A 1 60  ? 31.24030 -22.80661 -14.51111 1.000 21.29737 ? 60  TYR A OH  1 
ATOM   450  N  N   . TYR A 1 61  ? 37.96785 -17.75450 -13.76368 1.000 21.86908 ? 61  TYR A N   1 
ATOM   451  C  CA  . TYR A 1 61  ? 39.08264 -16.81559 -13.70543 1.000 23.99393 ? 61  TYR A CA  1 
ATOM   452  C  C   . TYR A 1 61  ? 38.97290 -15.86799 -12.51773 1.000 21.92030 ? 61  TYR A C   1 
ATOM   453  O  O   . TYR A 1 61  ? 39.99667 -15.41970 -11.98945 1.000 23.58515 ? 61  TYR A O   1 
ATOM   454  C  CB  . TYR A 1 61  ? 39.15770 -16.02326 -15.00942 1.000 21.11587 ? 61  TYR A CB  1 
ATOM   455  C  CG  . TYR A 1 61  ? 39.02120 -16.87803 -16.25065 1.000 24.57088 ? 61  TYR A CG  1 
ATOM   456  C  CD1 . TYR A 1 61  ? 40.12604 -17.50636 -16.80790 1.000 21.64341 ? 61  TYR A CD1 1 
ATOM   457  C  CD2 . TYR A 1 61  ? 37.78723 -17.05444 -16.86650 1.000 23.71736 ? 61  TYR A CD2 1 
ATOM   458  C  CE1 . TYR A 1 61  ? 40.00817 -18.28738 -17.94209 1.000 20.71129 ? 61  TYR A CE1 1 
ATOM   459  C  CE2 . TYR A 1 61  ? 37.65953 -17.83451 -18.00181 1.000 25.82021 ? 61  TYR A CE2 1 
ATOM   460  C  CZ  . TYR A 1 61  ? 38.77388 -18.44816 -18.53500 1.000 22.53086 ? 61  TYR A CZ  1 
ATOM   461  O  OH  . TYR A 1 61  ? 38.65662 -19.22568 -19.66451 1.000 22.71911 ? 61  TYR A OH  1 
ATOM   462  N  N   . SER A 1 62  ? 37.75681 -15.54912 -12.08574 1.000 22.18785 ? 62  SER A N   1 
ATOM   463  C  CA  . SER A 1 62  ? 37.54897 -14.62036 -10.98720 1.000 20.72667 ? 62  SER A CA  1 
ATOM   464  C  C   . SER A 1 62  ? 36.50295 -15.17247 -10.03021 1.000 22.85022 ? 62  SER A C   1 
ATOM   465  O  O   . SER A 1 62  ? 35.68138 -16.01986 -10.39007 1.000 20.09262 ? 62  SER A O   1 
ATOM   466  C  CB  . SER A 1 62  ? 37.11655 -13.23748 -11.49402 1.000 23.49302 ? 62  SER A CB  1 
ATOM   467  O  OG  . SER A 1 62  ? 36.77285 -12.38544 -10.41558 1.000 26.27377 ? 62  SER A OG  1 
ATOM   468  N  N   . SER A 1 63  ? 36.55193 -14.68100 -8.79550  1.000 17.15693 ? 63  SER A N   1 
ATOM   469  C  CA  . SER A 1 63  ? 35.56074 -15.01071 -7.78263  1.000 19.96549 ? 63  SER A CA  1 
ATOM   470  C  C   . SER A 1 63  ? 34.41698 -14.00695 -7.73824  1.000 19.00076 ? 63  SER A C   1 
ATOM   471  O  O   . SER A 1 63  ? 33.52017 -14.14440 -6.89971  1.000 23.44511 ? 63  SER A O   1 
ATOM   472  C  CB  . SER A 1 63  ? 36.22618 -15.09975 -6.40438  1.000 20.54555 ? 63  SER A CB  1 
ATOM   473  O  OG  . SER A 1 63  ? 36.84176 -13.87306 -6.05384  1.000 26.34481 ? 63  SER A OG  1 
ATOM   474  N  N   . ARG A 1 64  ? 34.42569 -13.01088 -8.61957  1.000 18.97979 ? 64  ARG A N   1 
ATOM   475  C  CA  . ARG A 1 64  ? 33.39766 -11.98210 -8.62101  1.000 18.41738 ? 64  ARG A CA  1 
ATOM   476  C  C   . ARG A 1 64  ? 32.11251 -12.50572 -9.24674  1.000 17.42978 ? 64  ARG A C   1 
ATOM   477  O  O   . ARG A 1 64  ? 32.13998 -13.28247 -10.20573 1.000 16.87664 ? 64  ARG A O   1 
ATOM   478  C  CB  . ARG A 1 64  ? 33.88174 -10.74704 -9.38141  1.000 18.41415 ? 64  ARG A CB  1 
ATOM   479  N  N   . ASP A 1 65  ? 30.98233 -12.07761 -8.69163  1.000 15.52998 ? 65  ASP A N   1 
ATOM   480  C  CA  . ASP A 1 65  ? 29.67129 -12.40797 -9.24332  1.000 14.04873 ? 65  ASP A CA  1 
ATOM   481  C  C   . ASP A 1 65  ? 29.37163 -11.41872 -10.36207 1.000 16.12569 ? 65  ASP A C   1 
ATOM   482  O  O   . ASP A 1 65  ? 28.91380 -10.30126 -10.11482 1.000 12.98670 ? 65  ASP A O   1 
ATOM   483  C  CB  . ASP A 1 65  ? 28.60368 -12.36448 -8.15518  1.000 12.00594 ? 65  ASP A CB  1 
ATOM   484  C  CG  . ASP A 1 65  ? 27.20696 -12.65009 -8.68615  1.000 12.40340 ? 65  ASP A CG  1 
ATOM   485  O  OD1 . ASP A 1 65  ? 27.07880 -13.15444 -9.82182  1.000 11.07633 ? 65  ASP A OD1 1 
ATOM   486  O  OD2 . ASP A 1 65  ? 26.23031 -12.36547 -7.96187  1.000 12.46129 ? 65  ASP A OD2 1 
ATOM   487  N  N   . GLY A 1 66  ? 29.63862 -11.82398 -11.59864 1.000 14.26862 ? 66  GLY A N   1 
ATOM   488  C  CA  . GLY A 1 66  ? 29.33815 -11.01241 -12.75675 1.000 14.29138 ? 66  GLY A CA  1 
ATOM   489  C  C   . GLY A 1 66  ? 27.93904 -11.18658 -13.30412 1.000 17.47004 ? 66  GLY A C   1 
ATOM   490  O  O   . GLY A 1 66  ? 27.63363 -10.65045 -14.37447 1.000 13.49933 ? 66  GLY A O   1 
ATOM   491  N  N   . ASN A 1 67  ? 27.07640 -11.91902 -12.60095 1.000 14.04944 ? 67  ASN A N   1 
ATOM   492  C  CA  . ASN A 1 67  ? 25.71598 -12.19652 -13.04198 1.000 14.40214 ? 67  ASN A CA  1 
ATOM   493  C  C   . ASN A 1 67  ? 24.66678 -11.56516 -12.14017 1.000 15.26514 ? 67  ASN A C   1 
ATOM   494  O  O   . ASN A 1 67  ? 23.79812 -10.83040 -12.62099 1.000 16.15709 ? 67  ASN A O   1 
ATOM   495  C  CB  . ASN A 1 67  ? 25.49270 -13.71626 -13.12030 1.000 13.11166 ? 67  ASN A CB  1 
ATOM   496  C  CG  . ASN A 1 67  ? 24.10469 -14.07982 -13.61265 1.000 15.30022 ? 67  ASN A CG  1 
ATOM   497  O  OD1 . ASN A 1 67  ? 23.14698 -14.11229 -12.83914 1.000 15.18183 ? 67  ASN A OD1 1 
ATOM   498  N  ND2 . ASN A 1 67  ? 23.99076 -14.36159 -14.90525 1.000 13.52325 ? 67  ASN A ND2 1 
ATOM   499  N  N   . GLY A 1 68  ? 24.72403 -11.83667 -10.83689 1.000 13.31401 ? 68  GLY A N   1 
ATOM   500  C  CA  . GLY A 1 68  ? 23.75448 -11.34651 -9.87976  1.000 11.55935 ? 68  GLY A CA  1 
ATOM   501  C  C   . GLY A 1 68  ? 22.86906 -12.42118 -9.28695  1.000 13.64268 ? 68  GLY A C   1 
ATOM   502  O  O   . GLY A 1 68  ? 22.24197 -12.18429 -8.24594  1.000 13.18543 ? 68  GLY A O   1 
ATOM   503  N  N   . HIS A 1 69  ? 22.80499 -13.59556 -9.91863  1.000 12.52301 ? 69  HIS A N   1 
ATOM   504  C  CA  . HIS A 1 69  ? 21.95581 -14.67542 -9.42312  1.000 10.35647 ? 69  HIS A CA  1 
ATOM   505  C  C   . HIS A 1 69  ? 22.39845 -15.13481 -8.03817  1.000 10.57765 ? 69  HIS A C   1 
ATOM   506  O  O   . HIS A 1 69  ? 21.57391 -15.29881 -7.13087  1.000 7.41739  ? 69  HIS A O   1 
ATOM   507  C  CB  . HIS A 1 69  ? 21.97736 -15.84091 -10.41452 1.000 10.42666 ? 69  HIS A CB  1 
ATOM   508  C  CG  . HIS A 1 69  ? 21.01739 -16.94168 -10.08585 1.000 10.65724 ? 69  HIS A CG  1 
ATOM   509  N  ND1 . HIS A 1 69  ? 21.40164 -18.09648 -9.43874  1.000 9.76644  ? 69  HIS A ND1 1 
ATOM   510  C  CD2 . HIS A 1 69  ? 19.69273 -17.07286 -10.33431 1.000 13.12213 ? 69  HIS A CD2 1 
ATOM   511  C  CE1 . HIS A 1 69  ? 20.35347 -18.88761 -9.29466  1.000 10.95699 ? 69  HIS A CE1 1 
ATOM   512  N  NE2 . HIS A 1 69  ? 19.30417 -18.28992 -9.82973  1.000 12.25503 ? 69  HIS A NE2 1 
ATOM   513  N  N   . GLY A 1 70  ? 23.70359 -15.34305 -7.85632  1.000 9.24575  ? 70  GLY A N   1 
ATOM   514  C  CA  . GLY A 1 70  ? 24.19483 -15.82064 -6.57390  1.000 9.64489  ? 70  GLY A CA  1 
ATOM   515  C  C   . GLY A 1 70  ? 24.08148 -14.78368 -5.47276  1.000 10.25660 ? 70  GLY A C   1 
ATOM   516  O  O   . GLY A 1 70  ? 23.78338 -15.11810 -4.32259  1.000 8.18195  ? 70  GLY A O   1 
ATOM   517  N  N   . THR A 1 71  ? 24.32530 -13.51325 -5.80440  1.000 8.82084  ? 71  THR A N   1 
ATOM   518  C  CA  . THR A 1 71  ? 24.15376 -12.44806 -4.82152  1.000 8.56293  ? 71  THR A CA  1 
ATOM   519  C  C   . THR A 1 71  ? 22.69747 -12.33330 -4.38957  1.000 9.86335  ? 71  THR A C   1 
ATOM   520  O  O   . THR A 1 71  ? 22.40647 -12.06652 -3.21709  1.000 7.86855  ? 71  THR A O   1 
ATOM   521  C  CB  . THR A 1 71  ? 24.64669 -11.11779 -5.39441  1.000 12.34926 ? 71  THR A CB  1 
ATOM   522  O  OG1 . THR A 1 71  ? 26.02094 -11.23921 -5.78391  1.000 11.16193 ? 71  THR A OG1 1 
ATOM   523  C  CG2 . THR A 1 71  ? 24.51457 -10.00529 -4.36283  1.000 12.10199 ? 71  THR A CG2 1 
ATOM   524  N  N   . HIS A 1 72  ? 21.76798 -12.53871 -5.32578  1.000 10.80279 ? 72  HIS A N   1 
ATOM   525  C  CA  . HIS A 1 72  ? 20.34916 -12.47160 -4.99490  1.000 9.88029  ? 72  HIS A CA  1 
ATOM   526  C  C   . HIS A 1 72  ? 19.94951 -13.59539 -4.04803  1.000 8.76405  ? 72  HIS A C   1 
ATOM   527  O  O   . HIS A 1 72  ? 19.20903 -13.36879 -3.08372  1.000 9.48631  ? 72  HIS A O   1 
ATOM   528  C  CB  . HIS A 1 72  ? 19.51637 -12.52323 -6.27533  1.000 11.57063 ? 72  HIS A CB  1 
ATOM   529  C  CG  . HIS A 1 72  ? 18.07534 -12.17173 -6.07522  1.000 10.84712 ? 72  HIS A CG  1 
ATOM   530  N  ND1 . HIS A 1 72  ? 17.14823 -13.07110 -5.59415  1.000 10.60983 ? 72  HIS A ND1 1 
ATOM   531  C  CD2 . HIS A 1 72  ? 17.40079 -11.01851 -6.29659  1.000 10.38512 ? 72  HIS A CD2 1 
ATOM   532  C  CE1 . HIS A 1 72  ? 15.96540 -12.48626 -5.52538  1.000 11.84932 ? 72  HIS A CE1 1 
ATOM   533  N  NE2 . HIS A 1 72  ? 16.09125 -11.24049 -5.94593  1.000 11.56416 ? 72  HIS A NE2 1 
ATOM   534  N  N   . CYS A 1 73  ? 20.43208 -14.81334 -4.30602  1.000 9.90732  ? 73  CYS A N   1 
ATOM   535  C  CA  . CYS A 1 73  ? 20.09485 -15.94234 -3.44562  1.000 10.61235 ? 73  CYS A CA  1 
ATOM   536  C  C   . CYS A 1 73  ? 20.71823 -15.79031 -2.06524  1.000 8.40870  ? 73  CYS A C   1 
ATOM   537  O  O   . CYS A 1 73  ? 20.07087 -16.07690 -1.05192  1.000 7.49188  ? 73  CYS A O   1 
ATOM   538  C  CB  . CYS A 1 73  ? 20.54616 -17.25080 -4.09503  1.000 10.62958 ? 73  CYS A CB  1 
ATOM   539  S  SG  . CYS A 1 73  ? 19.69739 -17.65577 -5.63715  1.000 12.12829 ? 73  CYS A SG  1 
ATOM   540  N  N   . ALA A 1 74  ? 21.97510 -15.34298 -2.00644  1.000 8.86293  ? 74  ALA A N   1 
ATOM   541  C  CA  . ALA A 1 74  ? 22.62687 -15.13349 -0.71798  1.000 8.54072  ? 74  ALA A CA  1 
ATOM   542  C  C   . ALA A 1 74  ? 21.90159 -14.07352 0.09951   1.000 9.24892  ? 74  ALA A C   1 
ATOM   543  O  O   . ALA A 1 74  ? 21.81857 -14.17618 1.32915   1.000 8.15091  ? 74  ALA A O   1 
ATOM   544  C  CB  . ALA A 1 74  ? 24.08955 -14.74271 -0.92639  1.000 8.24225  ? 74  ALA A CB  1 
ATOM   545  N  N   . GLY A 1 75  ? 21.36746 -13.04806 -0.56746  1.000 7.88691  ? 75  GLY A N   1 
ATOM   546  C  CA  . GLY A 1 75  ? 20.63330 -12.01638 0.14633   1.000 9.55365  ? 75  GLY A CA  1 
ATOM   547  C  C   . GLY A 1 75  ? 19.37921 -12.54689 0.81312   1.000 9.22556  ? 75  GLY A C   1 
ATOM   548  O  O   . GLY A 1 75  ? 19.02866 -12.12941 1.91890   1.000 10.60298 ? 75  GLY A O   1 
ATOM   549  N  N   . THR A 1 76  ? 18.68490 -13.47432 0.15010   1.000 9.18174  ? 76  THR A N   1 
ATOM   550  C  CA  . THR A 1 76  ? 17.51725 -14.09608 0.76409   1.000 8.51906  ? 76  THR A CA  1 
ATOM   551  C  C   . THR A 1 76  ? 17.91515 -14.99255 1.93097   1.000 7.87093  ? 76  THR A C   1 
ATOM   552  O  O   . THR A 1 76  ? 17.15207 -15.12915 2.89437   1.000 8.51963  ? 76  THR A O   1 
ATOM   553  C  CB  . THR A 1 76  ? 16.73159 -14.88657 -0.28523  1.000 9.93778  ? 76  THR A CB  1 
ATOM   554  O  OG1 . THR A 1 76  ? 16.36366 -14.01418 -1.36080  1.000 9.87577  ? 76  THR A OG1 1 
ATOM   555  C  CG2 . THR A 1 76  ? 15.46713 -15.48616 0.31714   1.000 9.00619  ? 76  THR A CG2 1 
ATOM   556  N  N   . VAL A 1 77  ? 19.10661 -15.59309 1.87578   1.000 10.34207 ? 77  VAL A N   1 
ATOM   557  C  CA  . VAL A 1 77  ? 19.57249 -16.42461 2.98434   1.000 10.69421 ? 77  VAL A CA  1 
ATOM   558  C  C   . VAL A 1 77  ? 19.80492 -15.57193 4.22473   1.000 11.34199 ? 77  VAL A C   1 
ATOM   559  O  O   . VAL A 1 77  ? 19.22309 -15.81732 5.28771   1.000 11.39376 ? 77  VAL A O   1 
ATOM   560  C  CB  . VAL A 1 77  ? 20.84813 -17.19226 2.59731   1.000 9.84403  ? 77  VAL A CB  1 
ATOM   561  C  CG1 . VAL A 1 77  ? 21.36976 -17.96715 3.79884   1.000 10.86122 ? 77  VAL A CG1 1 
ATOM   562  C  CG2 . VAL A 1 77  ? 20.58091 -18.13037 1.43903   1.000 10.26233 ? 77  VAL A CG2 1 
ATOM   563  N  N   . GLY A 1 78  ? 20.66507 -14.56046 4.11133   1.000 9.29967  ? 78  GLY A N   1 
ATOM   564  C  CA  . GLY A 1 78  ? 21.04009 -13.81766 5.29716   1.000 13.05895 ? 78  GLY A CA  1 
ATOM   565  C  C   . GLY A 1 78  ? 21.49095 -12.38248 5.12248   1.000 13.80972 ? 78  GLY A C   1 
ATOM   566  O  O   . GLY A 1 78  ? 22.40752 -11.93853 5.82009   1.000 15.41060 ? 78  GLY A O   1 
ATOM   567  N  N   . SER A 1 79  ? 20.86813 -11.63928 4.21396   1.000 14.77039 ? 79  SER A N   1 
ATOM   568  C  CA  . SER A 1 79  ? 21.10378 -10.20534 4.20241   1.000 13.38803 ? 79  SER A CA  1 
ATOM   569  C  C   . SER A 1 79  ? 20.32942 -9.54857  5.34162   1.000 13.56963 ? 79  SER A C   1 
ATOM   570  O  O   . SER A 1 79  ? 19.40782 -10.13267 5.91830   1.000 13.65312 ? 79  SER A O   1 
ATOM   571  C  CB  . SER A 1 79  ? 20.70182 -9.58871  2.86244   1.000 12.06900 ? 79  SER A CB  1 
ATOM   572  O  OG  . SER A 1 79  ? 19.31093 -9.72617  2.63186   1.000 12.88467 ? 79  SER A OG  1 
ATOM   573  N  N   . ARG A 1 80  ? 20.71975 -8.31495  5.66700   1.000 13.15139 ? 80  ARG A N   1 
ATOM   574  C  CA  . ARG A 1 80  ? 20.10547 -7.62018  6.79478   1.000 15.02125 ? 80  ARG A CA  1 
ATOM   575  C  C   . ARG A 1 80  ? 18.62476 -7.35944  6.54404   1.000 14.89480 ? 80  ARG A C   1 
ATOM   576  O  O   . ARG A 1 80  ? 17.77801 -7.64121  7.39982   1.000 11.90261 ? 80  ARG A O   1 
ATOM   577  C  CB  . ARG A 1 80  ? 20.84452 -6.30990  7.06776   1.000 12.37379 ? 80  ARG A CB  1 
ATOM   578  N  N   . THR A 1 81  ? 18.29246 -6.82818  5.36900   1.000 13.85213 ? 81  THR A N   1 
ATOM   579  C  CA  . THR A 1 81  ? 16.92027 -6.43976  5.06970   1.000 11.84156 ? 81  THR A CA  1 
ATOM   580  C  C   . THR A 1 81  ? 16.10904 -7.55820  4.42814   1.000 13.63811 ? 81  THR A C   1 
ATOM   581  O  O   . THR A 1 81  ? 14.91022 -7.67958  4.70601   1.000 16.60018 ? 81  THR A O   1 
ATOM   582  C  CB  . THR A 1 81  ? 16.91378 -5.21324  4.14972   1.000 16.43459 ? 81  THR A CB  1 
ATOM   583  O  OG1 . THR A 1 81  ? 17.73511 -4.18496  4.71789   1.000 16.41817 ? 81  THR A OG1 1 
ATOM   584  C  CG2 . THR A 1 81  ? 15.50018 -4.67656  3.96793   1.000 11.96262 ? 81  THR A CG2 1 
ATOM   585  N  N   . TYR A 1 82  ? 16.73088 -8.38966  3.59273   1.000 14.63394 ? 82  TYR A N   1 
ATOM   586  C  CA  . TYR A 1 82  ? 16.00631 -9.35060  2.77097   1.000 11.09261 ? 82  TYR A CA  1 
ATOM   587  C  C   . TYR A 1 82  ? 16.29060 -10.80065 3.14603   1.000 13.03284 ? 82  TYR A C   1 
ATOM   588  O  O   . TYR A 1 82  ? 15.85804 -11.70869 2.42847   1.000 11.92913 ? 82  TYR A O   1 
ATOM   589  C  CB  . TYR A 1 82  ? 16.33582 -9.11869  1.29440   1.000 11.64233 ? 82  TYR A CB  1 
ATOM   590  C  CG  . TYR A 1 82  ? 16.37841 -7.65679  0.90918   1.000 13.29383 ? 82  TYR A CG  1 
ATOM   591  C  CD1 . TYR A 1 82  ? 15.21001 -6.95503  0.64542   1.000 11.86490 ? 82  TYR A CD1 1 
ATOM   592  C  CD2 . TYR A 1 82  ? 17.58673 -6.97718  0.81552   1.000 12.27356 ? 82  TYR A CD2 1 
ATOM   593  C  CE1 . TYR A 1 82  ? 15.24285 -5.61849  0.29807   1.000 14.66255 ? 82  TYR A CE1 1 
ATOM   594  C  CE2 . TYR A 1 82  ? 17.62936 -5.63979  0.46836   1.000 13.35555 ? 82  TYR A CE2 1 
ATOM   595  C  CZ  . TYR A 1 82  ? 16.45425 -4.96615  0.21007   1.000 15.18112 ? 82  TYR A CZ  1 
ATOM   596  O  OH  . TYR A 1 82  ? 16.48922 -3.63513  -0.13649  1.000 19.47737 ? 82  TYR A OH  1 
ATOM   597  N  N   . GLY A 1 83  ? 16.98849 -11.04486 4.25057   1.000 13.80426 ? 83  GLY A N   1 
ATOM   598  C  CA  . GLY A 1 83  ? 17.41488 -12.38162 4.61491   1.000 8.90700  ? 83  GLY A CA  1 
ATOM   599  C  C   . GLY A 1 83  ? 16.53793 -13.03779 5.66554   1.000 15.44711 ? 83  GLY A C   1 
ATOM   600  O  O   . GLY A 1 83  ? 15.92333 -12.36898 6.49217   1.000 14.67822 ? 83  GLY A O   1 
ATOM   601  N  N   . VAL A 1 84  ? 16.48804 -14.37082 5.61827   1.000 9.89487  ? 84  VAL A N   1 
ATOM   602  C  CA  . VAL A 1 84  ? 15.78237 -15.12843 6.64803   1.000 13.08218 ? 84  VAL A CA  1 
ATOM   603  C  C   . VAL A 1 84  ? 16.59313 -15.14786 7.93801   1.000 13.07725 ? 84  VAL A C   1 
ATOM   604  O  O   . VAL A 1 84  ? 16.09111 -14.80205 9.01352   1.000 14.80044 ? 84  VAL A O   1 
ATOM   605  C  CB  . VAL A 1 84  ? 15.47845 -16.55543 6.15559   1.000 9.76444  ? 84  VAL A CB  1 
ATOM   606  C  CG1 . VAL A 1 84  ? 14.85678 -17.38066 7.27300   1.000 9.24128  ? 84  VAL A CG1 1 
ATOM   607  C  CG2 . VAL A 1 84  ? 14.56394 -16.52181 4.93987   1.000 12.94531 ? 84  VAL A CG2 1 
ATOM   608  N  N   . ALA A 1 85  ? 17.85812 -15.54806 7.84700   1.000 12.28954 ? 85  ALA A N   1 
ATOM   609  C  CA  . ALA A 1 85  ? 18.77744 -15.62624 8.98397   1.000 14.85845 ? 85  ALA A CA  1 
ATOM   610  C  C   . ALA A 1 85  ? 19.73884 -14.44088 8.88449   1.000 14.99672 ? 85  ALA A C   1 
ATOM   611  O  O   . ALA A 1 85  ? 20.80882 -14.53790 8.28034   1.000 10.99374 ? 85  ALA A O   1 
ATOM   612  C  CB  . ALA A 1 85  ? 19.52619 -16.95471 8.99190   1.000 11.67936 ? 85  ALA A CB  1 
ATOM   613  N  N   . LYS A 1 86  ? 19.36318 -13.32514 9.51439   1.000 13.41642 ? 86  LYS A N   1 
ATOM   614  C  CA  . LYS A 1 86  ? 20.06784 -12.05821 9.34367   1.000 13.15301 ? 86  LYS A CA  1 
ATOM   615  C  C   . LYS A 1 86  ? 21.42231 -12.00418 10.04109  1.000 15.23772 ? 86  LYS A C   1 
ATOM   616  O  O   . LYS A 1 86  ? 22.09098 -10.96915 9.94817   1.000 14.85766 ? 86  LYS A O   1 
ATOM   617  C  CB  . LYS A 1 86  ? 19.18884 -10.91388 9.84939   1.000 14.48877 ? 86  LYS A CB  1 
ATOM   618  C  CG  . LYS A 1 86  ? 17.81439 -10.87171 9.20727   1.000 15.20318 ? 86  LYS A CG  1 
ATOM   619  C  CD  . LYS A 1 86  ? 16.95943 -9.76735  9.79858   1.000 15.25202 ? 86  LYS A CD  1 
ATOM   620  C  CE  . LYS A 1 86  ? 15.56355 -9.78790  9.20289   1.000 15.98928 ? 86  LYS A CE  1 
ATOM   621  N  NZ  . LYS A 1 86  ? 15.59212 -9.63057  7.72177   1.000 12.60439 ? 86  LYS A NZ  1 
ATOM   622  N  N   . LYS A 1 87  ? 21.85268 -13.06438 10.72851  1.000 15.46208 ? 87  LYS A N   1 
ATOM   623  C  CA  . LYS A 1 87  ? 23.13841 -13.05287 11.41710  1.000 15.78453 ? 87  LYS A CA  1 
ATOM   624  C  C   . LYS A 1 87  ? 24.00231 -14.26302 11.07927  1.000 16.02258 ? 87  LYS A C   1 
ATOM   625  O  O   . LYS A 1 87  ? 25.00276 -14.50517 11.76610  1.000 12.96845 ? 87  LYS A O   1 
ATOM   626  C  CB  . LYS A 1 87  ? 22.93741 -12.96699 12.93606  1.000 18.04865 ? 87  LYS A CB  1 
ATOM   627  C  CG  . LYS A 1 87  ? 22.49408 -11.59774 13.43774  1.000 18.48232 ? 87  LYS A CG  1 
ATOM   628  C  CD  . LYS A 1 87  ? 22.14351 -11.64607 14.92020  1.000 21.71298 ? 87  LYS A CD  1 
ATOM   629  C  CE  . LYS A 1 87  ? 22.06176 -10.25186 15.53117  1.000 30.15411 ? 87  LYS A CE  1 
ATOM   630  N  NZ  . LYS A 1 87  ? 20.96310 -9.42832  14.95407  1.000 29.71893 ? 87  LYS A NZ  1 
ATOM   631  N  N   . THR A 1 88  ? 23.65165 -15.02205 10.04493  1.000 13.37035 ? 88  THR A N   1 
ATOM   632  C  CA  . THR A 1 88  ? 24.40690 -16.20972 9.68332   1.000 14.00684 ? 88  THR A CA  1 
ATOM   633  C  C   . THR A 1 88  ? 25.66035 -15.83291 8.89522   1.000 14.01232 ? 88  THR A C   1 
ATOM   634  O  O   . THR A 1 88  ? 25.82329 -14.70333 8.42549   1.000 12.80812 ? 88  THR A O   1 
ATOM   635  C  CB  . THR A 1 88  ? 23.54278 -17.16893 8.86538   1.000 11.83310 ? 88  THR A CB  1 
ATOM   636  O  OG1 . THR A 1 88  ? 24.22446 -18.42046 8.71279   1.000 13.25307 ? 88  THR A OG1 1 
ATOM   637  C  CG2 . THR A 1 88  ? 23.26209 -16.58434 7.48830   1.000 9.11734  ? 88  THR A CG2 1 
ATOM   638  N  N   . GLN A 1 89  ? 26.55539 -16.80555 8.75477   1.000 15.47012 ? 89  GLN A N   1 
ATOM   639  C  CA  . GLN A 1 89  ? 27.77962 -16.64808 7.98218   1.000 14.90062 ? 89  GLN A CA  1 
ATOM   640  C  C   . GLN A 1 89  ? 27.56267 -17.20528 6.58157   1.000 13.70665 ? 89  GLN A C   1 
ATOM   641  O  O   . GLN A 1 89  ? 27.03497 -18.31117 6.42326   1.000 14.97020 ? 89  GLN A O   1 
ATOM   642  C  CB  . GLN A 1 89  ? 28.94962 -17.35816 8.66448   1.000 16.94043 ? 89  GLN A CB  1 
ATOM   643  C  CG  . GLN A 1 89  ? 30.22416 -17.39470 7.83718   1.000 19.94562 ? 89  GLN A CG  1 
ATOM   644  C  CD  . GLN A 1 89  ? 30.90672 -16.04437 7.74478   1.000 23.10608 ? 89  GLN A CD  1 
ATOM   645  O  OE1 . GLN A 1 89  ? 30.96446 -15.29703 8.72092   1.000 24.54924 ? 89  GLN A OE1 1 
ATOM   646  N  NE2 . GLN A 1 89  ? 31.42955 -15.72475 6.56610   1.000 21.22942 ? 89  GLN A NE2 1 
ATOM   647  N  N   . LEU A 1 90  ? 27.97024 -16.44041 5.57294   1.000 11.80546 ? 90  LEU A N   1 
ATOM   648  C  CA  . LEU A 1 90  ? 27.72851 -16.77358 4.17473   1.000 13.03431 ? 90  LEU A CA  1 
ATOM   649  C  C   . LEU A 1 90  ? 29.05435 -17.07209 3.48711   1.000 13.91146 ? 90  LEU A C   1 
ATOM   650  O  O   . LEU A 1 90  ? 29.96891 -16.24125 3.50647   1.000 17.41582 ? 90  LEU A O   1 
ATOM   651  C  CB  . LEU A 1 90  ? 26.99909 -15.63148 3.46598   1.000 12.13616 ? 90  LEU A CB  1 
ATOM   652  C  CG  . LEU A 1 90  ? 25.54540 -15.39743 3.88055   1.000 11.78011 ? 90  LEU A CG  1 
ATOM   653  C  CD1 . LEU A 1 90  ? 25.02050 -14.08575 3.31759   1.000 14.19750 ? 90  LEU A CD1 1 
ATOM   654  C  CD2 . LEU A 1 90  ? 24.68339 -16.55903 3.42066   1.000 14.76047 ? 90  LEU A CD2 1 
ATOM   655  N  N   . PHE A 1 91  ? 29.15381 -18.25389 2.88325   1.000 10.65126 ? 91  PHE A N   1 
ATOM   656  C  CA  . PHE A 1 91  ? 30.31309 -18.64906 2.09509   1.000 13.15264 ? 91  PHE A CA  1 
ATOM   657  C  C   . PHE A 1 91  ? 29.89030 -18.81669 0.64282   1.000 12.37174 ? 91  PHE A C   1 
ATOM   658  O  O   . PHE A 1 91  ? 28.87887 -19.46918 0.36006   1.000 12.52224 ? 91  PHE A O   1 
ATOM   659  C  CB  . PHE A 1 91  ? 30.93064 -19.94906 2.61747   1.000 12.39772 ? 91  PHE A CB  1 
ATOM   660  C  CG  . PHE A 1 91  ? 31.47967 -19.84598 4.01116   1.000 13.41709 ? 91  PHE A CG  1 
ATOM   661  C  CD1 . PHE A 1 91  ? 32.45011 -18.90758 4.31992   1.000 18.54789 ? 91  PHE A CD1 1 
ATOM   662  C  CD2 . PHE A 1 91  ? 31.03790 -20.69946 5.00890   1.000 14.99493 ? 91  PHE A CD2 1 
ATOM   663  C  CE1 . PHE A 1 91  ? 32.96144 -18.81348 5.60061   1.000 17.08981 ? 91  PHE A CE1 1 
ATOM   664  C  CE2 . PHE A 1 91  ? 31.54682 -20.61137 6.29147   1.000 16.65572 ? 91  PHE A CE2 1 
ATOM   665  C  CZ  . PHE A 1 91  ? 32.51139 -19.66781 6.58654   1.000 16.96094 ? 91  PHE A CZ  1 
ATOM   666  N  N   . GLY A 1 92  ? 30.66077 -18.23357 -0.26927  1.000 10.90688 ? 92  GLY A N   1 
ATOM   667  C  CA  . GLY A 1 92  ? 30.34777 -18.27584 -1.68687  1.000 10.24237 ? 92  GLY A CA  1 
ATOM   668  C  C   . GLY A 1 92  ? 31.24558 -19.25194 -2.42455  1.000 11.43633 ? 92  GLY A C   1 
ATOM   669  O  O   . GLY A 1 92  ? 32.46925 -19.22674 -2.27304  1.000 13.01820 ? 92  GLY A O   1 
ATOM   670  N  N   . VAL A 1 93  ? 30.61887 -20.11513 -3.22075  1.000 8.45019  ? 93  VAL A N   1 
ATOM   671  C  CA  . VAL A 1 93  ? 31.31603 -21.07062 -4.07616  1.000 11.45389 ? 93  VAL A CA  1 
ATOM   672  C  C   . VAL A 1 93  ? 30.80877 -20.85059 -5.49461  1.000 11.32087 ? 93  VAL A C   1 
ATOM   673  O  O   . VAL A 1 93  ? 29.63108 -21.09890 -5.78163  1.000 12.67813 ? 93  VAL A O   1 
ATOM   674  C  CB  . VAL A 1 93  ? 31.09370 -22.52448 -3.63655  1.000 9.84581  ? 93  VAL A CB  1 
ATOM   675  C  CG1 . VAL A 1 93  ? 31.91855 -23.46874 -4.49921  1.000 12.21554 ? 93  VAL A CG1 1 
ATOM   676  C  CG2 . VAL A 1 93  ? 31.43711 -22.69776 -2.16408  1.000 10.83128 ? 93  VAL A CG2 1 
ATOM   677  N  N   . LYS A 1 94  ? 31.68945 -20.39082 -6.38036  1.000 10.76838 ? 94  LYS A N   1 
ATOM   678  C  CA  . LYS A 1 94  ? 31.30609 -20.02165 -7.74211  1.000 14.23148 ? 94  LYS A CA  1 
ATOM   679  C  C   . LYS A 1 94  ? 31.50067 -21.22335 -8.65950  1.000 13.28414 ? 94  LYS A C   1 
ATOM   680  O  O   . LYS A 1 94  ? 32.60934 -21.48919 -9.13038  1.000 14.50841 ? 94  LYS A O   1 
ATOM   681  C  CB  . LYS A 1 94  ? 32.11428 -18.81991 -8.21815  1.000 15.34287 ? 94  LYS A CB  1 
ATOM   682  C  CG  . LYS A 1 94  ? 31.75147 -18.34359 -9.61508  1.000 15.09389 ? 94  LYS A CG  1 
ATOM   683  C  CD  . LYS A 1 94  ? 32.49635 -17.06859 -9.97324  1.000 16.02569 ? 94  LYS A CD  1 
ATOM   684  C  CE  . LYS A 1 94  ? 32.20893 -16.64633 -11.40430 1.000 18.89360 ? 94  LYS A CE  1 
ATOM   685  N  NZ  . LYS A 1 94  ? 30.75307 -16.44970 -11.64840 1.000 16.59577 ? 94  LYS A NZ  1 
ATOM   686  N  N   . VAL A 1 95  ? 30.41181 -21.95115 -8.92140  1.000 12.34853 ? 95  VAL A N   1 
ATOM   687  C  CA  . VAL A 1 95  ? 30.43840 -23.06630 -9.86428  1.000 12.93892 ? 95  VAL A CA  1 
ATOM   688  C  C   . VAL A 1 95  ? 29.77142 -22.72549 -11.18900 1.000 14.53631 ? 95  VAL A C   1 
ATOM   689  O  O   . VAL A 1 95  ? 29.91179 -23.49316 -12.15548 1.000 14.47603 ? 95  VAL A O   1 
ATOM   690  C  CB  . VAL A 1 95  ? 29.77871 -24.32608 -9.26371  1.000 13.10426 ? 95  VAL A CB  1 
ATOM   691  C  CG1 . VAL A 1 95  ? 30.47956 -24.72964 -7.97567  1.000 14.60150 ? 95  VAL A CG1 1 
ATOM   692  C  CG2 . VAL A 1 95  ? 28.29631 -24.08481 -9.02692  1.000 9.81530  ? 95  VAL A CG2 1 
ATOM   693  N  N   . LEU A 1 96  ? 29.05077 -21.61129 -11.26657 1.000 15.44679 ? 96  LEU A N   1 
ATOM   694  C  CA  . LEU A 1 96  ? 28.41446 -21.15879 -12.49377 1.000 17.79732 ? 96  LEU A CA  1 
ATOM   695  C  C   . LEU A 1 96  ? 29.14917 -19.93428 -13.02159 1.000 17.09610 ? 96  LEU A C   1 
ATOM   696  O  O   . LEU A 1 96  ? 29.60628 -19.09134 -12.24216 1.000 19.03885 ? 96  LEU A O   1 
ATOM   697  C  CB  . LEU A 1 96  ? 26.93894 -20.82243 -12.25549 1.000 16.47370 ? 96  LEU A CB  1 
ATOM   698  C  CG  . LEU A 1 96  ? 26.08594 -21.89404 -11.57117 1.000 16.16996 ? 96  LEU A CG  1 
ATOM   699  C  CD1 . LEU A 1 96  ? 24.67872 -21.37786 -11.30366 1.000 11.52068 ? 96  LEU A CD1 1 
ATOM   700  C  CD2 . LEU A 1 96  ? 26.04484 -23.16308 -12.40810 1.000 14.80921 ? 96  LEU A CD2 1 
ATOM   701  N  N   . ASP A 1 97  ? 29.26481 -19.83845 -14.34474 1.000 18.85114 ? 97  ASP A N   1 
ATOM   702  C  CA  . ASP A 1 97  ? 29.91902 -18.68963 -14.95040 1.000 19.63601 ? 97  ASP A CA  1 
ATOM   703  C  C   . ASP A 1 97  ? 28.99858 -17.47049 -14.88725 1.000 18.39601 ? 97  ASP A C   1 
ATOM   704  O  O   . ASP A 1 97  ? 27.87214 -17.53030 -14.38544 1.000 14.60214 ? 97  ASP A O   1 
ATOM   705  C  CB  . ASP A 1 97  ? 30.35202 -19.01150 -16.38371 1.000 19.94419 ? 97  ASP A CB  1 
ATOM   706  C  CG  . ASP A 1 97  ? 29.20900 -19.50448 -17.26022 1.000 23.18144 ? 97  ASP A CG  1 
ATOM   707  O  OD1 . ASP A 1 97  ? 28.04516 -19.10689 -17.03886 1.000 26.90642 ? 97  ASP A OD1 1 
ATOM   708  O  OD2 . ASP A 1 97  ? 29.48089 -20.30056 -18.18308 1.000 23.33757 ? 97  ASP A OD2 1 
ATOM   709  N  N   . ASP A 1 98  ? 29.48332 -16.34317 -15.40769 1.000 17.43281 ? 98  ASP A N   1 
ATOM   710  C  CA  . ASP A 1 98  ? 28.71411 -15.10510 -15.35447 1.000 18.63311 ? 98  ASP A CA  1 
ATOM   711  C  C   . ASP A 1 98  ? 27.50101 -15.11229 -16.27690 1.000 16.07031 ? 98  ASP A C   1 
ATOM   712  O  O   . ASP A 1 98  ? 26.73598 -14.14137 -16.26539 1.000 16.58308 ? 98  ASP A O   1 
ATOM   713  C  CB  . ASP A 1 98  ? 29.61871 -13.91507 -15.67908 1.000 17.62510 ? 98  ASP A CB  1 
ATOM   714  C  CG  . ASP A 1 98  ? 30.67721 -13.68667 -14.61592 1.000 19.06577 ? 98  ASP A CG  1 
ATOM   715  O  OD1 . ASP A 1 98  ? 30.45532 -14.10565 -13.45954 1.000 14.73017 ? 98  ASP A OD1 1 
ATOM   716  O  OD2 . ASP A 1 98  ? 31.72816 -13.08971 -14.93168 1.000 22.90964 ? 98  ASP A OD2 1 
ATOM   717  N  N   . ASN A 1 99  ? 27.30286 -16.16556 -17.06662 1.000 17.80952 ? 99  ASN A N   1 
ATOM   718  C  CA  . ASN A 1 99  ? 26.08105 -16.34575 -17.83744 1.000 22.29625 ? 99  ASN A CA  1 
ATOM   719  C  C   . ASN A 1 99  ? 25.08184 -17.25896 -17.14197 1.000 21.46932 ? 99  ASN A C   1 
ATOM   720  O  O   . ASN A 1 99  ? 24.01102 -17.52305 -17.69758 1.000 22.69172 ? 99  ASN A O   1 
ATOM   721  C  CB  . ASN A 1 99  ? 26.40672 -16.90017 -19.22836 1.000 24.50788 ? 99  ASN A CB  1 
ATOM   722  C  CG  . ASN A 1 99  ? 27.04695 -15.86633 -20.13167 1.000 31.80679 ? 99  ASN A CG  1 
ATOM   723  O  OD1 . ASN A 1 99  ? 26.52771 -14.76243 -20.29606 1.000 33.76876 ? 99  ASN A OD1 1 
ATOM   724  N  ND2 . ASN A 1 99  ? 28.18611 -16.21614 -20.71725 1.000 31.11190 ? 99  ASN A ND2 1 
ATOM   725  N  N   . GLY A 1 100 ? 25.40348 -17.74379 -15.94496 1.000 20.05938 ? 100 GLY A N   1 
ATOM   726  C  CA  . GLY A 1 100 ? 24.51407 -18.62231 -15.21591 1.000 17.86752 ? 100 GLY A CA  1 
ATOM   727  C  C   . GLY A 1 100 ? 24.58157 -20.07900 -15.60881 1.000 19.80535 ? 100 GLY A C   1 
ATOM   728  O  O   . GLY A 1 100 ? 23.69361 -20.84737 -15.22326 1.000 25.91664 ? 100 GLY A O   1 
ATOM   729  N  N   . SER A 1 101 ? 25.60077 -20.48692 -16.35800 1.000 20.29385 ? 101 SER A N   1 
ATOM   730  C  CA  . SER A 1 101 ? 25.74362 -21.86065 -16.81284 1.000 22.08929 ? 101 SER A CA  1 
ATOM   731  C  C   . SER A 1 101 ? 26.96122 -22.51014 -16.16731 1.000 22.42044 ? 101 SER A C   1 
ATOM   732  O  O   . SER A 1 101 ? 27.85744 -21.83597 -15.65156 1.000 20.80176 ? 101 SER A O   1 
ATOM   733  C  CB  . SER A 1 101 ? 25.87197 -21.92682 -18.33896 1.000 25.70489 ? 101 SER A CB  1 
ATOM   734  O  OG  . SER A 1 101 ? 27.12518 -21.42108 -18.76663 1.000 37.30225 ? 101 SER A OG  1 
ATOM   735  N  N   . GLY A 1 102 ? 26.98409 -23.84012 -16.20956 1.000 18.66212 ? 102 GLY A N   1 
ATOM   736  C  CA  . GLY A 1 102 ? 28.08735 -24.59722 -15.65449 1.000 21.27423 ? 102 GLY A CA  1 
ATOM   737  C  C   . GLY A 1 102 ? 28.02828 -26.07336 -15.98648 1.000 22.51846 ? 102 GLY A C   1 
ATOM   738  O  O   . GLY A 1 102 ? 26.94649 -26.66626 -16.03757 1.000 20.63895 ? 102 GLY A O   1 
ATOM   739  N  N   . GLN A 1 103 ? 29.18957 -26.67656 -16.22401 1.000 18.52183 ? 103 GLN A N   1 
ATOM   740  C  CA  . GLN A 1 103 ? 29.24786 -28.10397 -16.49868 1.000 17.74697 ? 103 GLN A CA  1 
ATOM   741  C  C   . GLN A 1 103 ? 29.00764 -28.89357 -15.21797 1.000 18.91064 ? 103 GLN A C   1 
ATOM   742  O  O   . GLN A 1 103 ? 29.35239 -28.45518 -14.11676 1.000 17.95131 ? 103 GLN A O   1 
ATOM   743  C  CB  . GLN A 1 103 ? 30.59985 -28.48040 -17.10439 1.000 20.76570 ? 103 GLN A CB  1 
ATOM   744  N  N   . TYR A 1 104 ? 28.40000 -30.07105 -15.37284 1.000 15.89069 ? 104 TYR A N   1 
ATOM   745  C  CA  . TYR A 1 104 ? 28.08608 -30.90115 -14.21436 1.000 16.10734 ? 104 TYR A CA  1 
ATOM   746  C  C   . TYR A 1 104 ? 29.33987 -31.28727 -13.44158 1.000 15.51951 ? 104 TYR A C   1 
ATOM   747  O  O   . TYR A 1 104 ? 29.30832 -31.38826 -12.21041 1.000 16.67121 ? 104 TYR A O   1 
ATOM   748  C  CB  . TYR A 1 104 ? 27.33416 -32.15440 -14.65836 1.000 15.78478 ? 104 TYR A CB  1 
ATOM   749  C  CG  . TYR A 1 104 ? 25.84102 -31.96765 -14.80160 1.000 19.31782 ? 104 TYR A CG  1 
ATOM   750  C  CD1 . TYR A 1 104 ? 25.20774 -30.83726 -14.29632 1.000 17.74527 ? 104 TYR A CD1 1 
ATOM   751  C  CD2 . TYR A 1 104 ? 25.06234 -32.92874 -15.42857 1.000 15.86784 ? 104 TYR A CD2 1 
ATOM   752  C  CE1 . TYR A 1 104 ? 23.83996 -30.67084 -14.42193 1.000 17.22886 ? 104 TYR A CE1 1 
ATOM   753  C  CE2 . TYR A 1 104 ? 23.69935 -32.77222 -15.55837 1.000 15.42143 ? 104 TYR A CE2 1 
ATOM   754  C  CZ  . TYR A 1 104 ? 23.09205 -31.64222 -15.05374 1.000 17.10380 ? 104 TYR A CZ  1 
ATOM   755  O  OH  . TYR A 1 104 ? 21.73181 -31.49343 -15.18666 1.000 26.16490 ? 104 TYR A OH  1 
ATOM   756  N  N   . SER A 1 105 ? 30.45347 -31.50240 -14.14643 1.000 14.22577 ? 105 SER A N   1 
ATOM   757  C  CA  . SER A 1 105 ? 31.69015 -31.90022 -13.48296 1.000 19.91951 ? 105 SER A CA  1 
ATOM   758  C  C   . SER A 1 105 ? 32.19596 -30.81879 -12.53858 1.000 14.27210 ? 105 SER A C   1 
ATOM   759  O  O   . SER A 1 105 ? 32.81124 -31.12953 -11.51330 1.000 18.00891 ? 105 SER A O   1 
ATOM   760  C  CB  . SER A 1 105 ? 32.75356 -32.24084 -14.52774 1.000 18.76580 ? 105 SER A CB  1 
ATOM   761  O  OG  . SER A 1 105 ? 32.97326 -31.15211 -15.40756 1.000 25.37123 ? 105 SER A OG  1 
ATOM   762  N  N   . THR A 1 106 ? 31.94794 -29.54987 -12.86188 1.000 16.80439 ? 106 THR A N   1 
ATOM   763  C  CA  . THR A 1 106 ? 32.32330 -28.46635 -11.96103 1.000 16.58940 ? 106 THR A CA  1 
ATOM   764  C  C   . THR A 1 106 ? 31.35300 -28.35701 -10.78921 1.000 16.58830 ? 106 THR A C   1 
ATOM   765  O  O   . THR A 1 106 ? 31.76967 -28.07817 -9.65858  1.000 13.22988 ? 106 THR A O   1 
ATOM   766  C  CB  . THR A 1 106 ? 32.39631 -27.14908 -12.73536 1.000 18.55978 ? 106 THR A CB  1 
ATOM   767  O  OG1 . THR A 1 106 ? 33.41963 -27.24249 -13.73512 1.000 21.62097 ? 106 THR A OG1 1 
ATOM   768  C  CG2 . THR A 1 106 ? 32.71058 -25.98897 -11.80596 1.000 15.93399 ? 106 THR A CG2 1 
ATOM   769  N  N   . ILE A 1 107 ? 30.06113 -28.58650 -11.03782 1.000 13.63823 ? 107 ILE A N   1 
ATOM   770  C  CA  . ILE A 1 107 ? 29.07552 -28.55732 -9.95960  1.000 15.11047 ? 107 ILE A CA  1 
ATOM   771  C  C   . ILE A 1 107 ? 29.34741 -29.67376 -8.95733  1.000 14.26089 ? 107 ILE A C   1 
ATOM   772  O  O   . ILE A 1 107 ? 29.22480 -29.48121 -7.74089  1.000 13.94902 ? 107 ILE A O   1 
ATOM   773  C  CB  . ILE A 1 107 ? 27.65141 -28.64411 -10.54128 1.000 13.51858 ? 107 ILE A CB  1 
ATOM   774  C  CG1 . ILE A 1 107 ? 27.35506 -27.41429 -11.40111 1.000 13.63545 ? 107 ILE A CG1 1 
ATOM   775  C  CG2 . ILE A 1 107 ? 26.62120 -28.78062 -9.43298  1.000 11.42366 ? 107 ILE A CG2 1 
ATOM   776  C  CD1 . ILE A 1 107 ? 26.02438 -27.47573 -12.12013 1.000 19.01781 ? 107 ILE A CD1 1 
ATOM   777  N  N   . ILE A 1 108 ? 29.72869 -30.85501 -9.45082  1.000 12.08013 ? 108 ILE A N   1 
ATOM   778  C  CA  . ILE A 1 108 ? 30.05653 -31.96923 -8.56434  1.000 13.05384 ? 108 ILE A CA  1 
ATOM   779  C  C   . ILE A 1 108 ? 31.27874 -31.63616 -7.71786  1.000 11.77665 ? 108 ILE A C   1 
ATOM   780  O  O   . ILE A 1 108 ? 31.33197 -31.95367 -6.52279  1.000 12.19544 ? 108 ILE A O   1 
ATOM   781  C  CB  . ILE A 1 108 ? 30.26811 -33.25516 -9.38577  1.000 13.98812 ? 108 ILE A CB  1 
ATOM   782  C  CG1 . ILE A 1 108 ? 28.96284 -33.67951 -10.05899 1.000 10.97554 ? 108 ILE A CG1 1 
ATOM   783  C  CG2 . ILE A 1 108 ? 30.80793 -34.37658 -8.50925  1.000 11.97796 ? 108 ILE A CG2 1 
ATOM   784  C  CD1 . ILE A 1 108 ? 29.11842 -34.85768 -10.99252 1.000 13.07531 ? 108 ILE A CD1 1 
ATOM   785  N  N   . ALA A 1 109 ? 32.27842 -30.98889 -8.32209  1.000 12.91582 ? 109 ALA A N   1 
ATOM   786  C  CA  . ALA A 1 109 ? 33.47796 -30.61762 -7.57879  1.000 13.56502 ? 109 ALA A CA  1 
ATOM   787  C  C   . ALA A 1 109 ? 33.15940 -29.60917 -6.48248  1.000 13.53862 ? 109 ALA A C   1 
ATOM   788  O  O   . ALA A 1 109 ? 33.73903 -29.66344 -5.39146  1.000 12.99644 ? 109 ALA A O   1 
ATOM   789  C  CB  . ALA A 1 109 ? 34.53336 -30.05865 -8.53220  1.000 16.52411 ? 109 ALA A CB  1 
ATOM   790  N  N   . GLY A 1 110 ? 32.23926 -28.68135 -6.75330  1.000 11.08335 ? 110 GLY A N   1 
ATOM   791  C  CA  . GLY A 1 110 ? 31.87898 -27.69722 -5.74615  1.000 11.95104 ? 110 GLY A CA  1 
ATOM   792  C  C   . GLY A 1 110 ? 31.20437 -28.31635 -4.53765  1.000 12.58249 ? 110 GLY A C   1 
ATOM   793  O  O   . GLY A 1 110 ? 31.40946 -27.87226 -3.40559  1.000 12.50769 ? 110 GLY A O   1 
ATOM   794  N  N   . MET A 1 111 ? 30.39178 -29.35215 -4.75949  1.000 11.55697 ? 111 MET A N   1 
ATOM   795  C  CA  . MET A 1 111 ? 29.73877 -30.03058 -3.64436  1.000 9.53586  ? 111 MET A CA  1 
ATOM   796  C  C   . MET A 1 111 ? 30.74935 -30.80367 -2.80597  1.000 12.30411 ? 111 MET A C   1 
ATOM   797  O  O   . MET A 1 111 ? 30.74051 -30.71989 -1.57210  1.000 11.90023 ? 111 MET A O   1 
ATOM   798  C  CB  . MET A 1 111 ? 28.64333 -30.96287 -4.16075  1.000 12.33018 ? 111 MET A CB  1 
ATOM   799  C  CG  . MET A 1 111 ? 27.50146 -30.25743 -4.86889  1.000 13.03449 ? 111 MET A CG  1 
ATOM   800  S  SD  . MET A 1 111 ? 26.06686 -31.33533 -5.04673  1.000 18.37435 ? 111 MET A SD  1 
ATOM   801  C  CE  . MET A 1 111 ? 25.71197 -31.14632 -6.78974  1.000 13.69721 ? 111 MET A CE  1 
ATOM   802  N  N   . ASP A 1 112 ? 31.62735 -31.56902 -3.46174  1.000 10.65522 ? 112 ASP A N   1 
ATOM   803  C  CA  . ASP A 1 112 ? 32.67454 -32.28502 -2.73959  1.000 11.96008 ? 112 ASP A CA  1 
ATOM   804  C  C   . ASP A 1 112 ? 33.61091 -31.32677 -2.01701  1.000 13.21556 ? 112 ASP A C   1 
ATOM   805  O  O   . ASP A 1 112 ? 34.16941 -31.67492 -0.96996  1.000 10.95037 ? 112 ASP A O   1 
ATOM   806  C  CB  . ASP A 1 112 ? 33.46491 -33.17141 -3.70211  1.000 13.14867 ? 112 ASP A CB  1 
ATOM   807  C  CG  . ASP A 1 112 ? 32.65258 -34.34219 -4.21510  1.000 14.58603 ? 112 ASP A CG  1 
ATOM   808  O  OD1 . ASP A 1 112 ? 31.85566 -34.90090 -3.43317  1.000 18.12764 ? 112 ASP A OD1 1 
ATOM   809  O  OD2 . ASP A 1 112 ? 32.81026 -34.70487 -5.39952  1.000 15.12890 ? 112 ASP A OD2 1 
ATOM   810  N  N   . PHE A 1 113 ? 33.79890 -30.12225 -2.56147  1.000 11.89691 ? 113 PHE A N   1 
ATOM   811  C  CA  . PHE A 1 113 ? 34.60492 -29.11645 -1.87852  1.000 11.44164 ? 113 PHE A CA  1 
ATOM   812  C  C   . PHE A 1 113 ? 33.95569 -28.68326 -0.57038  1.000 11.07121 ? 113 PHE A C   1 
ATOM   813  O  O   . PHE A 1 113 ? 34.64025 -28.53517 0.44866   1.000 13.41124 ? 113 PHE A O   1 
ATOM   814  C  CB  . PHE A 1 113 ? 34.82272 -27.91075 -2.79373  1.000 12.10490 ? 113 PHE A CB  1 
ATOM   815  C  CG  . PHE A 1 113 ? 35.45094 -26.73068 -2.10521  1.000 13.52421 ? 113 PHE A CG  1 
ATOM   816  C  CD1 . PHE A 1 113 ? 36.82426 -26.65359 -1.95102  1.000 13.22937 ? 113 PHE A CD1 1 
ATOM   817  C  CD2 . PHE A 1 113 ? 34.66725 -25.69661 -1.61506  1.000 14.04313 ? 113 PHE A CD2 1 
ATOM   818  C  CE1 . PHE A 1 113 ? 37.40616 -25.57037 -1.31751  1.000 14.03595 ? 113 PHE A CE1 1 
ATOM   819  C  CE2 . PHE A 1 113 ? 35.24280 -24.61254 -0.97785  1.000 15.63866 ? 113 PHE A CE2 1 
ATOM   820  C  CZ  . PHE A 1 113 ? 36.61419 -24.54821 -0.83123  1.000 13.52020 ? 113 PHE A CZ  1 
ATOM   821  N  N   . VAL A 1 114 ? 32.63773 -28.46870 -0.58084  1.000 12.48569 ? 114 VAL A N   1 
ATOM   822  C  CA  . VAL A 1 114 ? 31.94958 -28.00616 0.62189   1.000 11.31619 ? 114 VAL A CA  1 
ATOM   823  C  C   . VAL A 1 114 ? 32.00558 -29.06947 1.71108   1.000 13.23515 ? 114 VAL A C   1 
ATOM   824  O  O   . VAL A 1 114 ? 32.19048 -28.75901 2.89498   1.000 12.13151 ? 114 VAL A O   1 
ATOM   825  C  CB  . VAL A 1 114 ? 30.49891 -27.60859 0.28818   1.000 10.42056 ? 114 VAL A CB  1 
ATOM   826  C  CG1 . VAL A 1 114 ? 29.71755 -27.31522 1.56008   1.000 11.57325 ? 114 VAL A CG1 1 
ATOM   827  C  CG2 . VAL A 1 114 ? 30.47895 -26.40209 -0.63688  1.000 10.66543 ? 114 VAL A CG2 1 
ATOM   828  N  N   . ALA A 1 115 ? 31.86634 -30.34143 1.32608   1.000 12.76217 ? 115 ALA A N   1 
ATOM   829  C  CA  . ALA A 1 115 ? 31.88336 -31.42487 2.30361   1.000 13.34595 ? 115 ALA A CA  1 
ATOM   830  C  C   . ALA A 1 115 ? 33.20922 -31.49391 3.04921   1.000 16.02201 ? 115 ALA A C   1 
ATOM   831  O  O   . ALA A 1 115 ? 33.25486 -31.96607 4.19098   1.000 13.73900 ? 115 ALA A O   1 
ATOM   832  C  CB  . ALA A 1 115 ? 31.59284 -32.75695 1.61275   1.000 13.69428 ? 115 ALA A CB  1 
ATOM   833  N  N   . SER A 1 116 ? 34.29298 -31.03205 2.42689   1.000 11.69094 ? 116 SER A N   1 
ATOM   834  C  CA  . SER A 1 116 ? 35.59682 -31.00316 3.07675   1.000 13.87375 ? 116 SER A CA  1 
ATOM   835  C  C   . SER A 1 116 ? 35.89799 -29.65248 3.71525   1.000 15.82194 ? 116 SER A C   1 
ATOM   836  O  O   . SER A 1 116 ? 36.46706 -29.60221 4.81080   1.000 14.31929 ? 116 SER A O   1 
ATOM   837  C  CB  . SER A 1 116 ? 36.69480 -31.35538 2.06891   1.000 13.95232 ? 116 SER A CB  1 
ATOM   838  O  OG  . SER A 1 116 ? 37.98264 -31.12450 2.61377   1.000 14.12901 ? 116 SER A OG  1 
ATOM   839  N  N   . ASP A 1 117 ? 35.51949 -28.55449 3.05384   1.000 13.72780 ? 117 ASP A N   1 
ATOM   840  C  CA  . ASP A 1 117 ? 35.87626 -27.22797 3.54928   1.000 14.26453 ? 117 ASP A CA  1 
ATOM   841  C  C   . ASP A 1 117 ? 35.18978 -26.90968 4.87104   1.000 14.74159 ? 117 ASP A C   1 
ATOM   842  O  O   . ASP A 1 117 ? 35.71699 -26.12534 5.66781   1.000 17.50506 ? 117 ASP A O   1 
ATOM   843  C  CB  . ASP A 1 117 ? 35.53056 -26.16551 2.50441   1.000 13.93348 ? 117 ASP A CB  1 
ATOM   844  C  CG  . ASP A 1 117 ? 35.86462 -24.75896 2.96783   1.000 15.35865 ? 117 ASP A CG  1 
ATOM   845  O  OD1 . ASP A 1 117 ? 37.05650 -24.38752 2.93759   1.000 15.02229 ? 117 ASP A OD1 1 
ATOM   846  O  OD2 . ASP A 1 117 ? 34.93443 -24.02615 3.36476   1.000 15.53328 ? 117 ASP A OD2 1 
ATOM   847  N  N   . LYS A 1 118 ? 34.02269 -27.50594 5.12750   1.000 13.69207 ? 118 LYS A N   1 
ATOM   848  C  CA  . LYS A 1 118 ? 33.32132 -27.24868 6.37987   1.000 17.36183 ? 118 LYS A CA  1 
ATOM   849  C  C   . LYS A 1 118 ? 34.11884 -27.70098 7.59583   1.000 19.87591 ? 118 LYS A C   1 
ATOM   850  O  O   . LYS A 1 118 ? 33.83676 -27.24623 8.70924   1.000 18.49604 ? 118 LYS A O   1 
ATOM   851  C  CB  . LYS A 1 118 ? 31.96069 -27.94556 6.37944   1.000 17.60283 ? 118 LYS A CB  1 
ATOM   852  C  CG  . LYS A 1 118 ? 32.04186 -29.44208 6.61882   1.000 19.63380 ? 118 LYS A CG  1 
ATOM   853  C  CD  . LYS A 1 118 ? 30.67806 -30.01897 6.93410   1.000 17.58245 ? 118 LYS A CD  1 
ATOM   854  C  CE  . LYS A 1 118 ? 30.78724 -31.45637 7.40690   1.000 19.71202 ? 118 LYS A CE  1 
ATOM   855  N  NZ  . LYS A 1 118 ? 31.46844 -32.31869 6.40400   1.000 19.53408 ? 118 LYS A NZ  1 
ATOM   856  N  N   . ASN A 1 119 ? 35.10670 -28.57860 7.41116   1.000 18.43068 ? 119 ASN A N   1 
ATOM   857  C  CA  . ASN A 1 119 ? 35.85472 -29.13817 8.52937   1.000 19.26444 ? 119 ASN A CA  1 
ATOM   858  C  C   . ASN A 1 119 ? 36.92953 -28.20154 9.06620   1.000 21.31891 ? 119 ASN A C   1 
ATOM   859  O  O   . ASN A 1 119 ? 37.53270 -28.51208 10.09893  1.000 26.39293 ? 119 ASN A O   1 
ATOM   860  C  CB  . ASN A 1 119 ? 36.49236 -30.46853 8.11923   1.000 18.84014 ? 119 ASN A CB  1 
ATOM   861  C  CG  . ASN A 1 119 ? 35.46195 -31.52074 7.75477   1.000 19.74045 ? 119 ASN A CG  1 
ATOM   862  O  OD1 . ASN A 1 119 ? 34.41142 -31.62327 8.38830   1.000 20.14945 ? 119 ASN A OD1 1 
ATOM   863  N  ND2 . ASN A 1 119 ? 35.75647 -32.30601 6.72455   1.000 19.22793 ? 119 ASN A ND2 1 
ATOM   864  N  N   . ASN A 1 120 ? 37.18992 -27.07470 8.39955   1.000 19.78044 ? 120 ASN A N   1 
ATOM   865  C  CA  . ASN A 1 120 ? 38.14323 -26.08602 8.89186   1.000 22.67986 ? 120 ASN A CA  1 
ATOM   866  C  C   . ASN A 1 120 ? 37.49649 -24.71930 9.09232   1.000 23.21031 ? 120 ASN A C   1 
ATOM   867  O  O   . ASN A 1 120 ? 38.19833 -23.70492 9.15018   1.000 24.74527 ? 120 ASN A O   1 
ATOM   868  C  CB  . ASN A 1 120 ? 39.35225 -25.98388 7.95761   1.000 30.06360 ? 120 ASN A CB  1 
ATOM   869  C  CG  . ASN A 1 120 ? 38.96206 -25.85532 6.49811   1.000 25.33847 ? 120 ASN A CG  1 
ATOM   870  O  OD1 . ASN A 1 120 ? 38.18013 -24.98231 6.12372   1.000 31.32627 ? 120 ASN A OD1 1 
ATOM   871  N  ND2 . ASN A 1 120 ? 39.51030 -26.73085 5.66319   1.000 23.66388 ? 120 ASN A ND2 1 
ATOM   872  N  N   . ARG A 1 121 ? 36.17280 -24.67432 9.19936   1.000 20.03325 ? 121 ARG A N   1 
ATOM   873  C  CA  . ARG A 1 121 ? 35.44169 -23.46833 9.55067   1.000 21.25352 ? 121 ARG A CA  1 
ATOM   874  C  C   . ARG A 1 121 ? 34.86129 -23.61874 10.95079  1.000 23.41046 ? 121 ARG A C   1 
ATOM   875  O  O   . ARG A 1 121 ? 34.69418 -24.73016 11.46056  1.000 22.27002 ? 121 ARG A O   1 
ATOM   876  C  CB  . ARG A 1 121 ? 34.31887 -23.19004 8.54549   1.000 17.11685 ? 121 ARG A CB  1 
ATOM   877  C  CG  . ARG A 1 121 ? 34.74694 -23.27861 7.09209   1.000 20.00105 ? 121 ARG A CG  1 
ATOM   878  C  CD  . ARG A 1 121 ? 35.71457 -22.16870 6.72570   1.000 24.16475 ? 121 ARG A CD  1 
ATOM   879  N  NE  . ARG A 1 121 ? 36.08731 -22.22815 5.31774   1.000 21.14170 ? 121 ARG A NE  1 
ATOM   880  C  CZ  . ARG A 1 121 ? 36.84884 -21.33328 4.70382   1.000 24.69217 ? 121 ARG A CZ  1 
ATOM   881  N  NH1 . ARG A 1 121 ? 37.33829 -20.28515 5.34570   1.000 21.19467 ? 121 ARG A NH1 1 
ATOM   882  N  NH2 . ARG A 1 121 ? 37.12323 -21.49229 3.41220   1.000 19.96271 ? 121 ARG A NH2 1 
ATOM   883  N  N   . ASN A 1 122 ? 34.55576 -22.48326 11.57422  1.000 20.21760 ? 122 ASN A N   1 
ATOM   884  C  CA  . ASN A 1 122 ? 33.95705 -22.45848 12.90738  1.000 21.48129 ? 122 ASN A CA  1 
ATOM   885  C  C   . ASN A 1 122 ? 32.46247 -22.20637 12.74466  1.000 20.71562 ? 122 ASN A C   1 
ATOM   886  O  O   . ASN A 1 122 ? 32.02392 -21.06158 12.60912  1.000 17.42637 ? 122 ASN A O   1 
ATOM   887  C  CB  . ASN A 1 122 ? 34.61378 -21.40024 13.78705  1.000 23.42332 ? 122 ASN A CB  1 
ATOM   888  C  CG  . ASN A 1 122 ? 34.18842 -21.50688 15.24039  1.000 26.41924 ? 122 ASN A CG  1 
ATOM   889  O  OD1 . ASN A 1 122 ? 33.44311 -22.41171 15.61691  1.000 26.02993 ? 122 ASN A OD1 1 
ATOM   890  N  ND2 . ASN A 1 122 ? 34.67160 -20.58782 16.06732  1.000 29.19402 ? 122 ASN A ND2 1 
ATOM   891  N  N   . CYS A 1 123 ? 31.68197 -23.28364 12.75698  1.000 19.82403 ? 123 CYS A N   1 
ATOM   892  C  CA  . CYS A 1 123 ? 30.23035 -23.22389 12.59458  1.000 15.90441 ? 123 CYS A CA  1 
ATOM   893  C  C   . CYS A 1 123 ? 29.59068 -24.09898 13.66445  1.000 18.11893 ? 123 CYS A C   1 
ATOM   894  O  O   . CYS A 1 123 ? 29.11579 -25.20565 13.38235  1.000 19.06497 ? 123 CYS A O   1 
ATOM   895  C  CB  . CYS A 1 123 ? 29.82537 -23.66902 11.18915  1.000 15.97608 ? 123 CYS A CB  1 
ATOM   896  S  SG  . CYS A 1 123 ? 30.74015 -22.82350 9.87569   1.000 13.77052 ? 123 CYS A SG  1 
ATOM   897  N  N   . PRO A 1 124 ? 29.56101 -23.62599 14.91351  1.000 17.14212 ? 124 PRO A N   1 
ATOM   898  C  CA  . PRO A 1 124 ? 29.11218 -24.49596 16.01390  1.000 16.68046 ? 124 PRO A CA  1 
ATOM   899  C  C   . PRO A 1 124 ? 27.65992 -24.93084 15.91294  1.000 19.23163 ? 124 PRO A C   1 
ATOM   900  O  O   . PRO A 1 124 ? 27.31851 -26.01519 16.40109  1.000 21.59671 ? 124 PRO A O   1 
ATOM   901  C  CB  . PRO A 1 124 ? 29.35697 -23.63209 17.26016  1.000 17.46175 ? 124 PRO A CB  1 
ATOM   902  C  CG  . PRO A 1 124 ? 29.35603 -22.22452 16.75508  1.000 19.78820 ? 124 PRO A CG  1 
ATOM   903  C  CD  . PRO A 1 124 ? 29.96889 -22.29338 15.39062  1.000 17.66896 ? 124 PRO A CD  1 
ATOM   904  N  N   . LYS A 1 125 ? 26.79199 -24.13195 15.29624  1.000 19.19202 ? 125 LYS A N   1 
ATOM   905  C  CA  . LYS A 1 125 ? 25.37276 -24.45816 15.25592  1.000 17.87321 ? 125 LYS A CA  1 
ATOM   906  C  C   . LYS A 1 125 ? 24.97215 -25.28701 14.04170  1.000 18.10460 ? 125 LYS A C   1 
ATOM   907  O  O   . LYS A 1 125 ? 23.85100 -25.80506 14.01249  1.000 17.12195 ? 125 LYS A O   1 
ATOM   908  C  CB  . LYS A 1 125 ? 24.53618 -23.17553 15.30082  1.000 16.20871 ? 125 LYS A CB  1 
ATOM   909  C  CG  . LYS A 1 125 ? 24.69386 -22.39736 16.59427  1.000 16.88382 ? 125 LYS A CG  1 
ATOM   910  C  CD  . LYS A 1 125 ? 24.34697 -23.26069 17.79667  1.000 20.58020 ? 125 LYS A CD  1 
ATOM   911  C  CE  . LYS A 1 125 ? 24.58867 -22.51173 19.09600  1.000 26.17507 ? 125 LYS A CE  1 
ATOM   912  N  NZ  . LYS A 1 125 ? 24.25761 -23.33781 20.28902  1.000 25.20894 ? 125 LYS A NZ  1 
ATOM   913  N  N   . GLY A 1 126 ? 25.84579 -25.43026 13.04832  1.000 18.71097 ? 126 GLY A N   1 
ATOM   914  C  CA  . GLY A 1 126 ? 25.53061 -26.25713 11.89935  1.000 16.49574 ? 126 GLY A CA  1 
ATOM   915  C  C   . GLY A 1 126 ? 25.94473 -25.66574 10.56780  1.000 13.91502 ? 126 GLY A C   1 
ATOM   916  O  O   . GLY A 1 126 ? 26.34857 -24.50165 10.49454  1.000 15.24259 ? 126 GLY A O   1 
ATOM   917  N  N   . VAL A 1 127 ? 25.84850 -26.46361 9.50482   1.000 14.30930 ? 127 VAL A N   1 
ATOM   918  C  CA  . VAL A 1 127 ? 26.23111 -26.05033 8.15975   1.000 11.94961 ? 127 VAL A CA  1 
ATOM   919  C  C   . VAL A 1 127 ? 25.07436 -26.33337 7.21005   1.000 12.13301 ? 127 VAL A C   1 
ATOM   920  O  O   . VAL A 1 127 ? 24.44852 -27.39756 7.27667   1.000 12.34535 ? 127 VAL A O   1 
ATOM   921  C  CB  . VAL A 1 127 ? 27.51147 -26.76975 7.68241   1.000 12.85554 ? 127 VAL A CB  1 
ATOM   922  C  CG1 . VAL A 1 127 ? 27.89664 -26.30751 6.28359   1.000 12.10533 ? 127 VAL A CG1 1 
ATOM   923  C  CG2 . VAL A 1 127 ? 28.65431 -26.53178 8.65744   1.000 12.47997 ? 127 VAL A CG2 1 
ATOM   924  N  N   . VAL A 1 128 ? 24.79200 -25.37657 6.32535   1.000 11.39445 ? 128 VAL A N   1 
ATOM   925  C  CA  . VAL A 1 128 ? 23.73404 -25.49258 5.33001   1.000 11.33441 ? 128 VAL A CA  1 
ATOM   926  C  C   . VAL A 1 128 ? 24.32587 -25.19305 3.95801   1.000 10.75299 ? 128 VAL A C   1 
ATOM   927  O  O   . VAL A 1 128 ? 25.25089 -24.38592 3.82368   1.000 10.66251 ? 128 VAL A O   1 
ATOM   928  C  CB  . VAL A 1 128 ? 22.55046 -24.54273 5.64270   1.000 10.90468 ? 128 VAL A CB  1 
ATOM   929  C  CG1 . VAL A 1 128 ? 21.41212 -24.73673 4.65028   1.000 10.16068 ? 128 VAL A CG1 1 
ATOM   930  C  CG2 . VAL A 1 128 ? 22.05548 -24.75464 7.06670   1.000 9.52485  ? 128 VAL A CG2 1 
ATOM   931  N  N   . ALA A 1 129 ? 23.79798 -25.86434 2.93426   1.000 9.46671  ? 129 ALA A N   1 
ATOM   932  C  CA  . ALA A 1 129 ? 24.19910 -25.63731 1.55129   1.000 12.00095 ? 129 ALA A CA  1 
ATOM   933  C  C   . ALA A 1 129 ? 22.96022 -25.37557 0.70851   1.000 11.26571 ? 129 ALA A C   1 
ATOM   934  O  O   . ALA A 1 129 ? 22.01299 -26.16793 0.72981   1.000 13.70805 ? 129 ALA A O   1 
ATOM   935  C  CB  . ALA A 1 129 ? 24.97833 -26.83194 0.99078   1.000 12.48241 ? 129 ALA A CB  1 
ATOM   936  N  N   . SER A 1 130 ? 22.97024 -24.27114 -0.03256  1.000 10.24427 ? 130 SER A N   1 
ATOM   937  C  CA  . SER A 1 130 ? 21.84895 -23.87085 -0.87441  1.000 11.72308 ? 130 SER A CA  1 
ATOM   938  C  C   . SER A 1 130 ? 22.27146 -23.95838 -2.33463  1.000 11.46173 ? 130 SER A C   1 
ATOM   939  O  O   . SER A 1 130 ? 23.22574 -23.29116 -2.74802  1.000 11.81574 ? 130 SER A O   1 
ATOM   940  C  CB  . SER A 1 130 ? 21.38502 -22.45498 -0.52990  1.000 9.88420  ? 130 SER A CB  1 
ATOM   941  O  OG  . SER A 1 130 ? 20.19743 -22.12087 -1.22797  1.000 11.40436 ? 130 SER A OG  1 
ATOM   942  N  N   . LEU A 1 131 ? 21.56072 -24.77414 -3.11043  1.000 9.81022  ? 131 LEU A N   1 
ATOM   943  C  CA  . LEU A 1 131 ? 21.86326 -24.99185 -4.52448  1.000 12.20550 ? 131 LEU A CA  1 
ATOM   944  C  C   . LEU A 1 131 ? 20.66028 -24.55879 -5.35811  1.000 12.38435 ? 131 LEU A C   1 
ATOM   945  O  O   . LEU A 1 131 ? 19.70152 -25.31935 -5.52108  1.000 14.03960 ? 131 LEU A O   1 
ATOM   946  C  CB  . LEU A 1 131 ? 22.22407 -26.45244 -4.79581  1.000 11.66369 ? 131 LEU A CB  1 
ATOM   947  C  CG  . LEU A 1 131 ? 23.55958 -26.97090 -4.24760  1.000 13.11729 ? 131 LEU A CG  1 
ATOM   948  C  CD1 . LEU A 1 131 ? 23.43312 -27.41229 -2.79569  1.000 18.39256 ? 131 LEU A CD1 1 
ATOM   949  C  CD2 . LEU A 1 131 ? 24.09666 -28.10152 -5.11435  1.000 16.30474 ? 131 LEU A CD2 1 
ATOM   950  N  N   . SER A 1 132 ? 20.71602 -23.34232 -5.88896  1.000 9.81149  ? 132 SER A N   1 
ATOM   951  C  CA  . SER A 1 132 ? 19.69018 -22.83351 -6.79874  1.000 10.66195 ? 132 SER A CA  1 
ATOM   952  C  C   . SER A 1 132 ? 20.10964 -23.06856 -8.24845  1.000 11.95198 ? 132 SER A C   1 
ATOM   953  O  O   . SER A 1 132 ? 20.33083 -22.14105 -9.02731  1.000 9.29062  ? 132 SER A O   1 
ATOM   954  C  CB  . SER A 1 132 ? 19.43102 -21.35506 -6.52583  1.000 10.36242 ? 132 SER A CB  1 
ATOM   955  O  OG  . SER A 1 132 ? 18.70518 -21.16758 -5.32439  1.000 10.77226 ? 132 SER A OG  1 
ATOM   956  N  N   . LEU A 1 133 ? 20.21864 -24.34790 -8.59760  1.000 10.89213 ? 133 LEU A N   1 
ATOM   957  C  CA  . LEU A 1 133 ? 20.68232 -24.74905 -9.91894  1.000 12.74574 ? 133 LEU A CA  1 
ATOM   958  C  C   . LEU A 1 133 ? 20.11433 -26.12449 -10.23549 1.000 16.70656 ? 133 LEU A C   1 
ATOM   959  O  O   . LEU A 1 133 ? 19.57444 -26.81062 -9.36503  1.000 13.72966 ? 133 LEU A O   1 
ATOM   960  C  CB  . LEU A 1 133 ? 22.21590 -24.74673 -9.99776  1.000 13.41855 ? 133 LEU A CB  1 
ATOM   961  C  CG  . LEU A 1 133 ? 22.99536 -25.45094 -8.87808  1.000 13.85957 ? 133 LEU A CG  1 
ATOM   962  C  CD1 . LEU A 1 133 ? 23.14400 -26.95450 -9.12075  1.000 17.32799 ? 133 LEU A CD1 1 
ATOM   963  C  CD2 . LEU A 1 133 ? 24.35699 -24.80048 -8.68987  1.000 12.89707 ? 133 LEU A CD2 1 
ATOM   964  N  N   . GLY A 1 134 ? 20.24908 -26.52238 -11.49351 1.000 16.81828 ? 134 GLY A N   1 
ATOM   965  C  CA  . GLY A 1 134 ? 19.80155 -27.83924 -11.89929 1.000 15.39234 ? 134 GLY A CA  1 
ATOM   966  C  C   . GLY A 1 134 ? 19.75198 -27.95746 -13.40350 1.000 20.58804 ? 134 GLY A C   1 
ATOM   967  O  O   . GLY A 1 134 ? 19.97531 -26.99483 -14.14338 1.000 21.06455 ? 134 GLY A O   1 
ATOM   968  N  N   . GLY A 1 135 ? 19.45215 -29.17392 -13.84538 1.000 19.89902 ? 135 GLY A N   1 
ATOM   969  C  CA  . GLY A 1 135 ? 19.30331 -29.46720 -15.25410 1.000 17.80029 ? 135 GLY A CA  1 
ATOM   970  C  C   . GLY A 1 135 ? 18.73105 -30.85072 -15.46518 1.000 16.03936 ? 135 GLY A C   1 
ATOM   971  O  O   . GLY A 1 135 ? 18.00411 -31.35495 -14.60770 1.000 15.91567 ? 135 GLY A O   1 
ATOM   972  N  N   . GLY A 1 136 ? 19.05536 -31.47644 -16.59021 1.000 14.17546 ? 136 GLY A N   1 
ATOM   973  C  CA  . GLY A 1 136 ? 18.57835 -32.81849 -16.87064 1.000 16.50327 ? 136 GLY A CA  1 
ATOM   974  C  C   . GLY A 1 136 ? 19.07639 -33.82718 -15.84953 1.000 15.59736 ? 136 GLY A C   1 
ATOM   975  O  O   . GLY A 1 136 ? 19.99664 -33.58250 -15.06919 1.000 16.30054 ? 136 GLY A O   1 
ATOM   976  N  N   . TYR A 1 137 ? 18.43924 -34.99745 -15.86238 1.000 13.70270 ? 137 TYR A N   1 
ATOM   977  C  CA  . TYR A 1 137 ? 18.76138 -36.03086 -14.88634 1.000 13.47598 ? 137 TYR A CA  1 
ATOM   978  C  C   . TYR A 1 137 ? 20.19808 -36.50837 -15.05155 1.000 15.90807 ? 137 TYR A C   1 
ATOM   979  O  O   . TYR A 1 137 ? 20.68538 -36.70610 -16.16856 1.000 12.56534 ? 137 TYR A O   1 
ATOM   980  C  CB  . TYR A 1 137 ? 17.80259 -37.22128 -15.01635 1.000 15.52879 ? 137 TYR A CB  1 
ATOM   981  C  CG  . TYR A 1 137 ? 18.11126 -38.34931 -14.04852 1.000 14.53464 ? 137 TYR A CG  1 
ATOM   982  C  CD1 . TYR A 1 137 ? 17.63736 -38.31923 -12.74184 1.000 16.12798 ? 137 TYR A CD1 1 
ATOM   983  C  CD2 . TYR A 1 137 ? 18.87779 -39.44228 -14.44070 1.000 15.56685 ? 137 TYR A CD2 1 
ATOM   984  C  CE1 . TYR A 1 137 ? 17.91747 -39.34447 -11.85446 1.000 17.06109 ? 137 TYR A CE1 1 
ATOM   985  C  CE2 . TYR A 1 137 ? 19.16319 -40.47092 -13.55775 1.000 17.42743 ? 137 TYR A CE2 1 
ATOM   986  C  CZ  . TYR A 1 137 ? 18.67954 -40.41621 -12.26736 1.000 18.58571 ? 137 TYR A CZ  1 
ATOM   987  O  OH  . TYR A 1 137 ? 18.95837 -41.43655 -11.38625 1.000 21.36598 ? 137 TYR A OH  1 
ATOM   988  N  N   . SER A 1 138 ? 20.87008 -36.70058 -13.92021 1.000 16.72370 ? 138 SER A N   1 
ATOM   989  C  CA  . SER A 1 138 ? 22.23336 -37.21598 -13.89842 1.000 16.74257 ? 138 SER A CA  1 
ATOM   990  C  C   . SER A 1 138 ? 22.44307 -37.93482 -12.57684 1.000 14.86741 ? 138 SER A C   1 
ATOM   991  O  O   . SER A 1 138 ? 22.29729 -37.32624 -11.51246 1.000 14.88855 ? 138 SER A O   1 
ATOM   992  C  CB  . SER A 1 138 ? 23.25535 -36.09120 -14.07097 1.000 16.13019 ? 138 SER A CB  1 
ATOM   993  O  OG  . SER A 1 138 ? 24.57304 -36.56565 -13.85251 1.000 20.97911 ? 138 SER A OG  1 
ATOM   994  N  N   . SER A 1 139 ? 22.77436 -39.22648 -12.64583 1.000 15.37610 ? 139 SER A N   1 
ATOM   995  C  CA  . SER A 1 139 ? 22.98828 -39.99799 -11.42651 1.000 19.79958 ? 139 SER A CA  1 
ATOM   996  C  C   . SER A 1 139 ? 24.24697 -39.55512 -10.69224 1.000 14.86031 ? 139 SER A C   1 
ATOM   997  O  O   . SER A 1 139 ? 24.33963 -39.72283 -9.47116  1.000 15.75195 ? 139 SER A O   1 
ATOM   998  C  CB  . SER A 1 139 ? 23.05842 -41.49000 -11.75318 1.000 19.39356 ? 139 SER A CB  1 
ATOM   999  O  OG  . SER A 1 139 ? 24.08442 -41.76084 -12.69115 1.000 22.98328 ? 139 SER A OG  1 
ATOM   1000 N  N   . SER A 1 140 ? 25.22212 -38.99299 -11.41015 1.000 17.42782 ? 140 SER A N   1 
ATOM   1001 C  CA  . SER A 1 140 ? 26.43027 -38.50731 -10.75107 1.000 15.70153 ? 140 SER A CA  1 
ATOM   1002 C  C   . SER A 1 140 ? 26.15203 -37.23984 -9.95249  1.000 13.78438 ? 140 SER A C   1 
ATOM   1003 O  O   . SER A 1 140 ? 26.70141 -37.05529 -8.86027  1.000 14.76748 ? 140 SER A O   1 
ATOM   1004 C  CB  . SER A 1 140 ? 27.53190 -38.26364 -11.78170 1.000 17.21831 ? 140 SER A CB  1 
ATOM   1005 O  OG  . SER A 1 140 ? 27.92729 -39.47552 -12.40022 1.000 28.64928 ? 140 SER A OG  1 
ATOM   1006 N  N   . VAL A 1 141 ? 25.30143 -36.35621 -10.47907 1.000 14.04180 ? 141 VAL A N   1 
ATOM   1007 C  CA  . VAL A 1 141 ? 24.95231 -35.13873 -9.75324  1.000 13.44691 ? 141 VAL A CA  1 
ATOM   1008 C  C   . VAL A 1 141 ? 24.13084 -35.47236 -8.51362  1.000 12.22058 ? 141 VAL A C   1 
ATOM   1009 O  O   . VAL A 1 141 ? 24.32863 -34.88294 -7.44396  1.000 13.41010 ? 141 VAL A O   1 
ATOM   1010 C  CB  . VAL A 1 141 ? 24.21202 -34.15872 -10.68226 1.000 13.82801 ? 141 VAL A CB  1 
ATOM   1011 C  CG1 . VAL A 1 141 ? 23.64664 -32.99064 -9.88931  1.000 12.63016 ? 141 VAL A CG1 1 
ATOM   1012 C  CG2 . VAL A 1 141 ? 25.14509 -33.65947 -11.77383 1.000 12.69812 ? 141 VAL A CG2 1 
ATOM   1013 N  N   . ASN A 1 142 ? 23.20246 -36.42516 -8.63304  1.000 12.36772 ? 142 ASN A N   1 
ATOM   1014 C  CA  . ASN A 1 142 ? 22.40935 -36.83391 -7.47805  1.000 11.98806 ? 142 ASN A CA  1 
ATOM   1015 C  C   . ASN A 1 142 ? 23.28327 -37.46366 -6.40186  1.000 13.53990 ? 142 ASN A C   1 
ATOM   1016 O  O   . ASN A 1 142 ? 23.06975 -37.23484 -5.20538  1.000 12.40445 ? 142 ASN A O   1 
ATOM   1017 C  CB  . ASN A 1 142 ? 21.31273 -37.80608 -7.91065  1.000 12.60249 ? 142 ASN A CB  1 
ATOM   1018 C  CG  . ASN A 1 142 ? 20.13370 -37.10561 -8.54979  1.000 13.62595 ? 142 ASN A CG  1 
ATOM   1019 O  OD1 . ASN A 1 142 ? 20.21202 -35.92972 -8.89980  1.000 14.11088 ? 142 ASN A OD1 1 
ATOM   1020 N  ND2 . ASN A 1 142 ? 19.02887 -37.82572 -8.70124  1.000 13.45299 ? 142 ASN A ND2 1 
ATOM   1021 N  N   . SER A 1 143 ? 24.27299 -38.26214 -6.80773  1.000 12.03798 ? 143 SER A N   1 
ATOM   1022 C  CA  . SER A 1 143 ? 25.15289 -38.89864 -5.83356  1.000 12.36758 ? 143 SER A CA  1 
ATOM   1023 C  C   . SER A 1 143 ? 26.02516 -37.87228 -5.12278  1.000 11.44590 ? 143 SER A C   1 
ATOM   1024 O  O   . SER A 1 143 ? 26.32417 -38.02329 -3.93254  1.000 11.65647 ? 143 SER A O   1 
ATOM   1025 C  CB  . SER A 1 143 ? 26.01600 -39.95793 -6.51770  1.000 13.39157 ? 143 SER A CB  1 
ATOM   1026 O  OG  . SER A 1 143 ? 25.22421 -41.04051 -6.97511  1.000 18.34675 ? 143 SER A OG  1 
ATOM   1027 N  N   . ALA A 1 144 ? 26.44230 -36.82192 -5.83418  1.000 9.70347  ? 144 ALA A N   1 
ATOM   1028 C  CA  . ALA A 1 144 ? 27.23845 -35.77440 -5.20305  1.000 14.70931 ? 144 ALA A CA  1 
ATOM   1029 C  C   . ALA A 1 144 ? 26.42450 -35.01945 -4.16036  1.000 12.49634 ? 144 ALA A C   1 
ATOM   1030 O  O   . ALA A 1 144 ? 26.94172 -34.67224 -3.09205  1.000 10.97402 ? 144 ALA A O   1 
ATOM   1031 C  CB  . ALA A 1 144 ? 27.78144 -34.81462 -6.26162  1.000 11.06311 ? 144 ALA A CB  1 
ATOM   1032 N  N   . ALA A 1 145 ? 25.14807 -34.75752 -4.45196  1.000 11.00300 ? 145 ALA A N   1 
ATOM   1033 C  CA  . ALA A 1 145 ? 24.28254 -34.11840 -3.46691  1.000 11.87190 ? 145 ALA A CA  1 
ATOM   1034 C  C   . ALA A 1 145 ? 24.04487 -35.03098 -2.27093  1.000 10.74952 ? 145 ALA A C   1 
ATOM   1035 O  O   . ALA A 1 145 ? 23.97815 -34.56216 -1.12849  1.000 8.98426  ? 145 ALA A O   1 
ATOM   1036 C  CB  . ALA A 1 145 ? 22.95612 -33.71832 -4.11261  1.000 11.24237 ? 145 ALA A CB  1 
ATOM   1037 N  N   . ALA A 1 146 ? 23.91827 -36.33822 -2.51321  1.000 12.11661 ? 146 ALA A N   1 
ATOM   1038 C  CA  . ALA A 1 146 ? 23.72267 -37.27682 -1.41311  1.000 10.13018 ? 146 ALA A CA  1 
ATOM   1039 C  C   . ALA A 1 146 ? 24.96809 -37.37390 -0.54015  1.000 12.09621 ? 146 ALA A C   1 
ATOM   1040 O  O   . ALA A 1 146 ? 24.86381 -37.48636 0.68730   1.000 12.89587 ? 146 ALA A O   1 
ATOM   1041 C  CB  . ALA A 1 146 ? 23.33732 -38.65205 -1.95571  1.000 10.57373 ? 146 ALA A CB  1 
ATOM   1042 N  N   . ARG A 1 147 ? 26.15444 -37.33629 -1.15372  1.000 10.39298 ? 147 ARG A N   1 
ATOM   1043 C  CA  . ARG A 1 147 ? 27.39050 -37.34422 -0.37673  1.000 11.12927 ? 147 ARG A CA  1 
ATOM   1044 C  C   . ARG A 1 147 ? 27.48526 -36.10795 0.50787   1.000 10.67146 ? 147 ARG A C   1 
ATOM   1045 O  O   . ARG A 1 147 ? 27.85009 -36.19812 1.68591   1.000 12.00081 ? 147 ARG A O   1 
ATOM   1046 C  CB  . ARG A 1 147 ? 28.60297 -37.42915 -1.30602  1.000 12.09432 ? 147 ARG A CB  1 
ATOM   1047 C  CG  . ARG A 1 147 ? 28.78284 -38.77001 -1.99729  1.000 14.58712 ? 147 ARG A CG  1 
ATOM   1048 C  CD  . ARG A 1 147 ? 30.18161 -38.90165 -2.58366  1.000 12.85514 ? 147 ARG A CD  1 
ATOM   1049 N  NE  . ARG A 1 147 ? 30.50085 -37.81611 -3.50259  1.000 16.47772 ? 147 ARG A NE  1 
ATOM   1050 C  CZ  . ARG A 1 147 ? 30.20565 -37.81897 -4.79507  1.000 15.55749 ? 147 ARG A CZ  1 
ATOM   1051 N  NH1 . ARG A 1 147 ? 29.57446 -38.83687 -5.35727  1.000 13.27226 ? 147 ARG A NH1 1 
ATOM   1052 N  NH2 . ARG A 1 147 ? 30.55008 -36.77334 -5.54158  1.000 11.75254 ? 147 ARG A NH2 1 
ATOM   1053 N  N   . LEU A 1 148 ? 27.15960 -34.93894 -0.04991  1.000 9.04117  ? 148 LEU A N   1 
ATOM   1054 C  CA  . LEU A 1 148 ? 27.20038 -33.70518 0.72789   1.000 12.65200 ? 148 LEU A CA  1 
ATOM   1055 C  C   . LEU A 1 148 ? 26.23483 -33.76446 1.90485   1.000 10.26963 ? 148 LEU A C   1 
ATOM   1056 O  O   . LEU A 1 148 ? 26.57111 -33.33832 3.01617   1.000 12.57911 ? 148 LEU A O   1 
ATOM   1057 C  CB  . LEU A 1 148 ? 26.88289 -32.51256 -0.17486  1.000 9.73500  ? 148 LEU A CB  1 
ATOM   1058 C  CG  . LEU A 1 148 ? 26.95381 -31.12418 0.45991   1.000 11.94759 ? 148 LEU A CG  1 
ATOM   1059 C  CD1 . LEU A 1 148 ? 28.33471 -30.87997 1.04662   1.000 12.44915 ? 148 LEU A CD1 1 
ATOM   1060 C  CD2 . LEU A 1 148 ? 26.60223 -30.05035 -0.55727  1.000 13.47038 ? 148 LEU A CD2 1 
ATOM   1061 N  N   . GLN A 1 149 ? 25.03145 -34.29810 1.68114   1.000 10.87835 ? 149 GLN A N   1 
ATOM   1062 C  CA  . GLN A 1 149 ? 24.07392 -34.44837 2.77175   1.000 12.58132 ? 149 GLN A CA  1 
ATOM   1063 C  C   . GLN A 1 149 ? 24.58242 -35.43034 3.81979   1.000 13.10159 ? 149 GLN A C   1 
ATOM   1064 O  O   . GLN A 1 149 ? 24.44605 -35.19008 5.02520   1.000 13.14545 ? 149 GLN A O   1 
ATOM   1065 C  CB  . GLN A 1 149 ? 22.72222 -34.90630 2.22264   1.000 10.30417 ? 149 GLN A CB  1 
ATOM   1066 C  CG  . GLN A 1 149 ? 21.66705 -35.14266 3.29149   1.000 16.61932 ? 149 GLN A CG  1 
ATOM   1067 C  CD  . GLN A 1 149 ? 21.15364 -33.85203 3.89868   1.000 12.26666 ? 149 GLN A CD  1 
ATOM   1068 O  OE1 . GLN A 1 149 ? 20.95259 -32.86109 3.19724   1.000 8.33803  ? 149 GLN A OE1 1 
ATOM   1069 N  NE2 . GLN A 1 149 ? 20.94131 -33.85664 5.20953   1.000 13.50954 ? 149 GLN A NE2 1 
ATOM   1070 N  N   . SER A 1 150 ? 25.17852 -36.54134 3.37797   1.000 13.86412 ? 150 SER A N   1 
ATOM   1071 C  CA  . SER A 1 150 ? 25.64736 -37.55709 4.31548   1.000 12.56096 ? 150 SER A CA  1 
ATOM   1072 C  C   . SER A 1 150 ? 26.79819 -37.04979 5.17469   1.000 15.31615 ? 150 SER A C   1 
ATOM   1073 O  O   . SER A 1 150 ? 26.95449 -37.48671 6.32101   1.000 15.69219 ? 150 SER A O   1 
ATOM   1074 C  CB  . SER A 1 150 ? 26.07129 -38.81612 3.55857   1.000 15.04641 ? 150 SER A CB  1 
ATOM   1075 O  OG  . SER A 1 150 ? 24.97435 -39.39876 2.87660   1.000 21.95050 ? 150 SER A OG  1 
ATOM   1076 N  N   . SER A 1 151 ? 27.61089 -36.13166 4.64734   1.000 12.12158 ? 151 SER A N   1 
ATOM   1077 C  CA  . SER A 1 151 ? 28.74540 -35.61495 5.40381   1.000 14.90752 ? 151 SER A CA  1 
ATOM   1078 C  C   . SER A 1 151 ? 28.32537 -34.74586 6.58212   1.000 15.88946 ? 151 SER A C   1 
ATOM   1079 O  O   . SER A 1 151 ? 29.17690 -34.40548 7.41026   1.000 14.46871 ? 151 SER A O   1 
ATOM   1080 C  CB  . SER A 1 151 ? 29.67489 -34.81829 4.48467   1.000 14.71091 ? 151 SER A CB  1 
ATOM   1081 O  OG  . SER A 1 151 ? 29.07513 -33.60042 4.07916   1.000 14.52945 ? 151 SER A OG  1 
ATOM   1082 N  N   . GLY A 1 152 ? 27.05490 -34.38350 6.67864   1.000 12.90271 ? 152 GLY A N   1 
ATOM   1083 C  CA  . GLY A 1 152 ? 26.55258 -33.58881 7.77265   1.000 14.69219 ? 152 GLY A CA  1 
ATOM   1084 C  C   . GLY A 1 152 ? 26.10150 -32.18015 7.42464   1.000 14.17303 ? 152 GLY A C   1 
ATOM   1085 O  O   . GLY A 1 152 ? 26.07342 -31.32578 8.31991   1.000 13.86049 ? 152 GLY A O   1 
ATOM   1086 N  N   . VAL A 1 153 ? 25.74878 -31.91378 6.16909   1.000 13.81820 ? 153 VAL A N   1 
ATOM   1087 C  CA  . VAL A 1 153 ? 25.30793 -30.59649 5.72547   1.000 13.03981 ? 153 VAL A CA  1 
ATOM   1088 C  C   . VAL A 1 153 ? 23.85485 -30.68828 5.28382   1.000 12.75027 ? 153 VAL A C   1 
ATOM   1089 O  O   . VAL A 1 153 ? 23.46915 -31.62373 4.57222   1.000 15.99815 ? 153 VAL A O   1 
ATOM   1090 C  CB  . VAL A 1 153 ? 26.18852 -30.05953 4.57927   1.000 13.18934 ? 153 VAL A CB  1 
ATOM   1091 C  CG1 . VAL A 1 153 ? 25.69839 -28.69501 4.12314   1.000 13.44064 ? 153 VAL A CG1 1 
ATOM   1092 C  CG2 . VAL A 1 153 ? 27.64349 -29.99373 5.00854   1.000 11.97653 ? 153 VAL A CG2 1 
ATOM   1093 N  N   . MET A 1 154 ? 23.04826 -29.71726 5.70877   1.000 12.25896 ? 154 MET A N   1 
ATOM   1094 C  CA  . MET A 1 154 ? 21.67453 -29.59881 5.23082   1.000 11.48450 ? 154 MET A CA  1 
ATOM   1095 C  C   . MET A 1 154 ? 21.71075 -29.06001 3.80693   1.000 13.00008 ? 154 MET A C   1 
ATOM   1096 O  O   . MET A 1 154 ? 22.12638 -27.91937 3.57603   1.000 12.32869 ? 154 MET A O   1 
ATOM   1097 C  CB  . MET A 1 154 ? 20.85654 -28.68997 6.14404   1.000 14.65909 ? 154 MET A CB  1 
ATOM   1098 C  CG  . MET A 1 154 ? 19.34958 -28.72206 5.87940   1.000 13.73244 ? 154 MET A CG  1 
ATOM   1099 S  SD  . MET A 1 154 ? 18.80785 -27.73339 4.46937   1.000 14.55659 ? 154 MET A SD  1 
ATOM   1100 C  CE  . MET A 1 154 ? 17.06356 -28.14925 4.40959   1.000 11.03337 ? 154 MET A CE  1 
ATOM   1101 N  N   . VAL A 1 155 ? 21.28518 -29.87827 2.85127   1.000 12.89725 ? 155 VAL A N   1 
ATOM   1102 C  CA  . VAL A 1 155 ? 21.31753 -29.52226 1.43858   1.000 12.98880 ? 155 VAL A CA  1 
ATOM   1103 C  C   . VAL A 1 155 ? 19.89989 -29.19256 0.99419   1.000 11.74051 ? 155 VAL A C   1 
ATOM   1104 O  O   . VAL A 1 155 ? 18.98607 -30.01362 1.14051   1.000 9.80198  ? 155 VAL A O   1 
ATOM   1105 C  CB  . VAL A 1 155 ? 21.91595 -30.65366 0.58856   1.000 11.12370 ? 155 VAL A CB  1 
ATOM   1106 C  CG1 . VAL A 1 155 ? 21.93269 -30.26392 -0.88190  1.000 10.42067 ? 155 VAL A CG1 1 
ATOM   1107 C  CG2 . VAL A 1 155 ? 23.31728 -30.98919 1.07076   1.000 13.12363 ? 155 VAL A CG2 1 
ATOM   1108 N  N   . ALA A 1 156 ? 19.71525 -27.98806 0.46008   1.000 12.15129 ? 156 ALA A N   1 
ATOM   1109 C  CA  . ALA A 1 156 ? 18.44792 -27.55445 -0.11070  1.000 9.59149  ? 156 ALA A CA  1 
ATOM   1110 C  C   . ALA A 1 156 ? 18.65935 -27.24306 -1.58440  1.000 11.72102 ? 156 ALA A C   1 
ATOM   1111 O  O   . ALA A 1 156 ? 19.54141 -26.45129 -1.93430  1.000 11.83864 ? 156 ALA A O   1 
ATOM   1112 C  CB  . ALA A 1 156 ? 17.89795 -26.32897 0.62343   1.000 11.25327 ? 156 ALA A CB  1 
ATOM   1113 N  N   . VAL A 1 157 ? 17.85904 -27.86960 -2.44444  1.000 10.56245 ? 157 VAL A N   1 
ATOM   1114 C  CA  . VAL A 1 157 ? 18.00680 -27.72663 -3.88600  1.000 10.82662 ? 157 VAL A CA  1 
ATOM   1115 C  C   . VAL A 1 157 ? 16.68235 -27.27366 -4.48252  1.000 11.30344 ? 157 VAL A C   1 
ATOM   1116 O  O   . VAL A 1 157 ? 15.60848 -27.51374 -3.92102  1.000 11.24764 ? 157 VAL A O   1 
ATOM   1117 C  CB  . VAL A 1 157 ? 18.48488 -29.03903 -4.54995  1.000 9.53090  ? 157 VAL A CB  1 
ATOM   1118 C  CG1 . VAL A 1 157 ? 19.77085 -29.52754 -3.89763  1.000 10.73708 ? 157 VAL A CG1 1 
ATOM   1119 C  CG2 . VAL A 1 157 ? 17.40315 -30.10573 -4.47561  1.000 11.82359 ? 157 VAL A CG2 1 
ATOM   1120 N  N   . ALA A 1 158 ? 16.76828 -26.60463 -5.62952  1.000 9.04375  ? 158 ALA A N   1 
ATOM   1121 C  CA  . ALA A 1 158 ? 15.58307 -26.12237 -6.32270  1.000 9.66511  ? 158 ALA A CA  1 
ATOM   1122 C  C   . ALA A 1 158 ? 14.95047 -27.24247 -7.13650  1.000 10.59125 ? 158 ALA A C   1 
ATOM   1123 O  O   . ALA A 1 158 ? 15.64686 -28.10291 -7.68236  1.000 9.45184  ? 158 ALA A O   1 
ATOM   1124 C  CB  . ALA A 1 158 ? 15.93753 -24.94814 -7.23514  1.000 9.05328  ? 158 ALA A CB  1 
ATOM   1125 N  N   . ALA A 1 159 ? 13.61853 -27.22574 -7.21764  1.000 10.31500 ? 159 ALA A N   1 
ATOM   1126 C  CA  . ALA A 1 159 ? 12.89890 -28.25635 -7.95521  1.000 13.41211 ? 159 ALA A CA  1 
ATOM   1127 C  C   . ALA A 1 159 ? 12.91763 -28.02880 -9.46002  1.000 13.46782 ? 159 ALA A C   1 
ATOM   1128 O  O   . ALA A 1 159 ? 12.75394 -28.99000 -10.21901 1.000 13.52063 ? 159 ALA A O   1 
ATOM   1129 C  CB  . ALA A 1 159 ? 11.45039 -28.34216 -7.46839  1.000 12.95320 ? 159 ALA A CB  1 
ATOM   1130 N  N   . GLY A 1 160 ? 13.11037 -26.79770 -9.90511  1.000 10.34199 ? 160 GLY A N   1 
ATOM   1131 C  CA  . GLY A 1 160 ? 13.13841 -26.49548 -11.31851 1.000 12.93166 ? 160 GLY A CA  1 
ATOM   1132 C  C   . GLY A 1 160 ? 11.95683 -25.63498 -11.73984 1.000 12.49382 ? 160 GLY A C   1 
ATOM   1133 O  O   . GLY A 1 160 ? 10.92300 -25.55984 -11.06771 1.000 12.97610 ? 160 GLY A O   1 
ATOM   1134 N  N   . ASN A 1 161 ? 12.12532 -24.97858 -12.88440 1.000 11.21946 ? 161 ASN A N   1 
ATOM   1135 C  CA  . ASN A 1 161 ? 11.14102 -24.04966 -13.42427 1.000 13.01282 ? 161 ASN A CA  1 
ATOM   1136 C  C   . ASN A 1 161 ? 10.57298 -24.55558 -14.74587 1.000 13.89023 ? 161 ASN A C   1 
ATOM   1137 O  O   . ASN A 1 161 ? 10.42076 -23.79951 -15.70712 1.000 15.12516 ? 161 ASN A O   1 
ATOM   1138 C  CB  . ASN A 1 161 ? 11.74847 -22.65983 -13.60444 1.000 11.86473 ? 161 ASN A CB  1 
ATOM   1139 C  CG  . ASN A 1 161 ? 12.37595 -22.12645 -12.33297 1.000 14.91963 ? 161 ASN A CG  1 
ATOM   1140 O  OD1 . ASN A 1 161 ? 11.97668 -22.49315 -11.22772 1.000 15.39800 ? 161 ASN A OD1 1 
ATOM   1141 N  ND2 . ASN A 1 161 ? 13.36271 -21.25326 -12.48325 1.000 16.31102 ? 161 ASN A ND2 1 
ATOM   1142 N  N   . ASN A 1 162 ? 10.24112 -25.84325 -14.81052 1.000 14.25859 ? 162 ASN A N   1 
ATOM   1143 C  CA  . ASN A 1 162 ? 9.75409  -26.44963 -16.04164 1.000 14.16220 ? 162 ASN A CA  1 
ATOM   1144 C  C   . ASN A 1 162 ? 8.26151  -26.75176 -16.01829 1.000 16.60160 ? 162 ASN A C   1 
ATOM   1145 O  O   . ASN A 1 162 ? 7.72107  -27.18909 -17.04074 1.000 15.56223 ? 162 ASN A O   1 
ATOM   1146 C  CB  . ASN A 1 162 ? 10.53119 -27.73790 -16.34124 1.000 15.05119 ? 162 ASN A CB  1 
ATOM   1147 C  CG  . ASN A 1 162 ? 12.03517 -27.55073 -16.24367 1.000 21.61946 ? 162 ASN A CG  1 
ATOM   1148 O  OD1 . ASN A 1 162 ? 12.65138 -27.90021 -15.23674 1.000 20.38627 ? 162 ASN A OD1 1 
ATOM   1149 N  ND2 . ASN A 1 162 ? 12.63310 -26.99561 -17.29197 1.000 24.36565 ? 162 ASN A ND2 1 
ATOM   1150 N  N   . ASN A 1 163 ? 7.58214  -26.52395 -14.89105 1.000 13.08277 ? 163 ASN A N   1 
ATOM   1151 C  CA  . ASN A 1 163 ? 6.17495  -26.89882 -14.72703 1.000 14.85874 ? 163 ASN A CA  1 
ATOM   1152 C  C   . ASN A 1 163 ? 5.97277  -28.37564 -15.05717 1.000 14.90931 ? 163 ASN A C   1 
ATOM   1153 O  O   . ASN A 1 163 ? 4.98882  -28.77135 -15.68534 1.000 14.03860 ? 163 ASN A O   1 
ATOM   1154 C  CB  . ASN A 1 163 ? 5.25833  -26.01250 -15.57702 1.000 14.32246 ? 163 ASN A CB  1 
ATOM   1155 C  CG  . ASN A 1 163 ? 3.78604  -26.18659 -15.23154 1.000 16.47587 ? 163 ASN A CG  1 
ATOM   1156 O  OD1 . ASN A 1 163 ? 3.43714  -26.52145 -14.09914 1.000 17.41397 ? 163 ASN A OD1 1 
ATOM   1157 N  ND2 . ASN A 1 163 ? 2.91719  -25.97032 -16.21346 1.000 18.85443 ? 163 ASN A ND2 1 
ATOM   1158 N  N   . ALA A 1 164 ? 6.92829  -29.19943 -14.63750 1.000 13.58770 ? 164 ALA A N   1 
ATOM   1159 C  CA  . ALA A 1 164 ? 6.92774  -30.62439 -14.92685 1.000 16.56546 ? 164 ALA A CA  1 
ATOM   1160 C  C   . ALA A 1 164 ? 7.25862  -31.38943 -13.65211 1.000 17.89776 ? 164 ALA A C   1 
ATOM   1161 O  O   . ALA A 1 164 ? 7.45899  -30.80548 -12.58346 1.000 14.54588 ? 164 ALA A O   1 
ATOM   1162 C  CB  . ALA A 1 164 ? 7.92100  -30.95986 -16.04749 1.000 17.91520 ? 164 ALA A CB  1 
ATOM   1163 N  N   . ASP A 1 165 ? 7.30623  -32.71258 -13.76646 1.000 16.72765 ? 165 ASP A N   1 
ATOM   1164 C  CA  . ASP A 1 165 ? 7.68118  -33.54162 -12.63107 1.000 18.11339 ? 165 ASP A CA  1 
ATOM   1165 C  C   . ASP A 1 165 ? 9.18302  -33.43573 -12.39941 1.000 16.25491 ? 165 ASP A C   1 
ATOM   1166 O  O   . ASP A 1 165 ? 9.98092  -33.65770 -13.31568 1.000 14.64403 ? 165 ASP A O   1 
ATOM   1167 C  CB  . ASP A 1 165 ? 7.27009  -34.99369 -12.87571 1.000 15.13028 ? 165 ASP A CB  1 
ATOM   1168 C  CG  . ASP A 1 165 ? 7.28389  -35.82893 -11.60792 1.000 18.49280 ? 165 ASP A CG  1 
ATOM   1169 O  OD1 . ASP A 1 165 ? 8.27673  -35.76235 -10.85494 1.000 17.22446 ? 165 ASP A OD1 1 
ATOM   1170 O  OD2 . ASP A 1 165 ? 6.29576  -36.55237 -11.36307 1.000 20.85404 ? 165 ASP A OD2 1 
ATOM   1171 N  N   . ALA A 1 166 ? 9.56789  -33.09151 -11.17017 1.000 15.05105 ? 166 ALA A N   1 
ATOM   1172 C  CA  . ALA A 1 166 ? 10.97388 -32.89323 -10.84132 1.000 13.87970 ? 166 ALA A CA  1 
ATOM   1173 C  C   . ALA A 1 166 ? 11.78120 -34.18375 -10.84145 1.000 15.69518 ? 166 ALA A C   1 
ATOM   1174 O  O   . ALA A 1 166 ? 12.98742 -34.12849 -10.57937 1.000 16.60888 ? 166 ALA A O   1 
ATOM   1175 C  CB  . ALA A 1 166 ? 11.10111 -32.21245 -9.47602  1.000 14.55311 ? 166 ALA A CB  1 
ATOM   1176 N  N   . ARG A 1 167 ? 11.16422 -35.33385 -11.12063 1.000 17.31916 ? 167 ARG A N   1 
ATOM   1177 C  CA  . ARG A 1 167 ? 11.90592 -36.58792 -11.12894 1.000 13.25055 ? 167 ARG A CA  1 
ATOM   1178 C  C   . ARG A 1 167 ? 12.85475 -36.68808 -12.31408 1.000 13.53106 ? 167 ARG A C   1 
ATOM   1179 O  O   . ARG A 1 167 ? 13.73834 -37.55009 -12.31163 1.000 16.65896 ? 167 ARG A O   1 
ATOM   1180 C  CB  . ARG A 1 167 ? 10.93808 -37.77410 -11.13324 1.000 16.14079 ? 167 ARG A CB  1 
ATOM   1181 N  N   . ASN A 1 168 ? 12.69772 -35.82760 -13.31927 1.000 16.09448 ? 168 ASN A N   1 
ATOM   1182 C  CA  . ASN A 1 168 ? 13.55177 -35.82631 -14.49750 1.000 12.75446 ? 168 ASN A CA  1 
ATOM   1183 C  C   . ASN A 1 168 ? 14.61907 -34.74045 -14.44272 1.000 12.93798 ? 168 ASN A C   1 
ATOM   1184 O  O   . ASN A 1 168 ? 15.17262 -34.37249 -15.48372 1.000 12.39693 ? 168 ASN A O   1 
ATOM   1185 C  CB  . ASN A 1 168 ? 12.70251 -35.67115 -15.75936 1.000 14.69656 ? 168 ASN A CB  1 
ATOM   1186 C  CG  . ASN A 1 168 ? 11.89220 -36.91104 -16.06759 1.000 16.62539 ? 168 ASN A CG  1 
ATOM   1187 O  OD1 . ASN A 1 168 ? 12.35849 -38.03302 -15.87360 1.000 14.83624 ? 168 ASN A OD1 1 
ATOM   1188 N  ND2 . ASN A 1 168 ? 10.66913 -36.71650 -16.54698 1.000 15.11533 ? 168 ASN A ND2 1 
ATOM   1189 N  N   . TYR A 1 169 ? 14.92553 -34.22497 -13.25433 1.000 13.66648 ? 169 TYR A N   1 
ATOM   1190 C  CA  . TYR A 1 169 ? 15.89316 -33.14803 -13.12012 1.000 14.90837 ? 169 TYR A CA  1 
ATOM   1191 C  C   . TYR A 1 169 ? 16.77686 -33.39474 -11.90686 1.000 15.28486 ? 169 TYR A C   1 
ATOM   1192 O  O   . TYR A 1 169 ? 16.33893 -33.95720 -10.90025 1.000 15.30849 ? 169 TYR A O   1 
ATOM   1193 C  CB  . TYR A 1 169 ? 15.19900 -31.78469 -13.01074 1.000 14.12842 ? 169 TYR A CB  1 
ATOM   1194 C  CG  . TYR A 1 169 ? 14.36756 -31.43685 -14.22568 1.000 15.81809 ? 169 TYR A CG  1 
ATOM   1195 C  CD1 . TYR A 1 169 ? 14.94262 -30.82993 -15.33535 1.000 15.61395 ? 169 TYR A CD1 1 
ATOM   1196 C  CD2 . TYR A 1 169 ? 13.00921 -31.72290 -14.26628 1.000 16.55498 ? 169 TYR A CD2 1 
ATOM   1197 C  CE1 . TYR A 1 169 ? 14.18668 -30.51364 -16.44938 1.000 18.54777 ? 169 TYR A CE1 1 
ATOM   1198 C  CE2 . TYR A 1 169 ? 12.24518 -31.41045 -15.37538 1.000 16.70704 ? 169 TYR A CE2 1 
ATOM   1199 C  CZ  . TYR A 1 169 ? 12.83847 -30.80658 -16.46352 1.000 19.40878 ? 169 TYR A CZ  1 
ATOM   1200 O  OH  . TYR A 1 169 ? 12.07998 -30.49402 -17.56842 1.000 23.58779 ? 169 TYR A OH  1 
ATOM   1201 N  N   . SER A 1 170 ? 18.03032 -32.95958 -12.01509 1.000 14.36346 ? 170 SER A N   1 
ATOM   1202 C  CA  . SER A 1 170 ? 19.03144 -33.18615 -10.98899 1.000 14.53468 ? 170 SER A CA  1 
ATOM   1203 C  C   . SER A 1 170 ? 19.66159 -31.86657 -10.56621 1.000 15.72029 ? 170 SER A C   1 
ATOM   1204 O  O   . SER A 1 170 ? 19.84369 -30.96946 -11.39804 1.000 14.40624 ? 170 SER A O   1 
ATOM   1205 C  CB  . SER A 1 170 ? 20.11965 -34.14311 -11.49429 1.000 12.15590 ? 170 SER A CB  1 
ATOM   1206 O  OG  . SER A 1 170 ? 19.59891 -35.44790 -11.67820 1.000 14.71337 ? 170 SER A OG  1 
ATOM   1207 N  N   . PRO A 1 171 ? 20.01900 -31.72020 -9.28249  1.000 12.88669 ? 171 PRO A N   1 
ATOM   1208 C  CA  . PRO A 1 171 ? 19.89163 -32.69996 -8.19264  1.000 14.65716 ? 171 PRO A CA  1 
ATOM   1209 C  C   . PRO A 1 171 ? 18.52503 -32.67971 -7.51541  1.000 12.07050 ? 171 PRO A C   1 
ATOM   1210 O  O   . PRO A 1 171 ? 18.39456 -33.09714 -6.36791  1.000 14.51834 ? 171 PRO A O   1 
ATOM   1211 C  CB  . PRO A 1 171 ? 21.00035 -32.26650 -7.22905  1.000 10.74099 ? 171 PRO A CB  1 
ATOM   1212 C  CG  . PRO A 1 171 ? 21.01564 -30.77123 -7.37343  1.000 11.28136 ? 171 PRO A CG  1 
ATOM   1213 C  CD  . PRO A 1 171 ? 20.74569 -30.51519 -8.84107  1.000 14.98554 ? 171 PRO A CD  1 
ATOM   1214 N  N   . ALA A 1 172 ? 17.48532 -32.19997 -8.20256  1.000 12.10044 ? 172 ALA A N   1 
ATOM   1215 C  CA  . ALA A 1 172 ? 16.16383 -32.12475 -7.58767  1.000 13.69115 ? 172 ALA A CA  1 
ATOM   1216 C  C   . ALA A 1 172 ? 15.58918 -33.50734 -7.30588  1.000 15.71609 ? 172 ALA A C   1 
ATOM   1217 O  O   . ALA A 1 172 ? 14.85460 -33.68527 -6.32712  1.000 14.57459 ? 172 ALA A O   1 
ATOM   1218 C  CB  . ALA A 1 172 ? 15.21318 -31.33130 -8.48346  1.000 13.13208 ? 172 ALA A CB  1 
ATOM   1219 N  N   . SER A 1 173 ? 15.91184 -34.49538 -8.14002  1.000 10.45624 ? 173 SER A N   1 
ATOM   1220 C  CA  . SER A 1 173 ? 15.33832 -35.83031 -8.01838  1.000 13.62703 ? 173 SER A CA  1 
ATOM   1221 C  C   . SER A 1 173 ? 16.06431 -36.71016 -7.00726  1.000 15.02978 ? 173 SER A C   1 
ATOM   1222 O  O   . SER A 1 173 ? 15.73485 -37.89630 -6.90089  1.000 16.27479 ? 173 SER A O   1 
ATOM   1223 C  CB  . SER A 1 173 ? 15.32062 -36.52352 -9.38451  1.000 16.84504 ? 173 SER A CB  1 
ATOM   1224 O  OG  . SER A 1 173 ? 16.62680 -36.62218 -9.92559  1.000 14.20145 ? 173 SER A OG  1 
ATOM   1225 N  N   . GLU A 1 174 ? 17.03298 -36.17523 -6.27418  1.000 13.63029 ? 174 GLU A N   1 
ATOM   1226 C  CA  . GLU A 1 174 ? 17.69395 -36.94987 -5.23096  1.000 11.66083 ? 174 GLU A CA  1 
ATOM   1227 C  C   . GLU A 1 174 ? 16.82708 -36.96073 -3.97781  1.000 11.84405 ? 174 GLU A C   1 
ATOM   1228 O  O   . GLU A 1 174 ? 16.56679 -35.89469 -3.40915  1.000 11.36605 ? 174 GLU A O   1 
ATOM   1229 C  CB  . GLU A 1 174 ? 19.06956 -36.37627 -4.91856  1.000 12.17916 ? 174 GLU A CB  1 
ATOM   1230 C  CG  . GLU A 1 174 ? 19.68034 -36.89994 -3.62439  1.000 12.25677 ? 174 GLU A CG  1 
ATOM   1231 C  CD  . GLU A 1 174 ? 19.80910 -38.41387 -3.59493  1.000 11.07102 ? 174 GLU A CD  1 
ATOM   1232 O  OE1 . GLU A 1 174 ? 20.01983 -39.02614 -4.66356  1.000 10.67706 ? 174 GLU A OE1 1 
ATOM   1233 O  OE2 . GLU A 1 174 ? 19.69690 -38.99578 -2.49689  1.000 12.15348 ? 174 GLU A OE2 1 
ATOM   1234 N  N   . PRO A 1 175 ? 16.36130 -38.12550 -3.51917  1.000 14.23958 ? 175 PRO A N   1 
ATOM   1235 C  CA  . PRO A 1 175 ? 15.41220 -38.13756 -2.39428  1.000 12.54194 ? 175 PRO A CA  1 
ATOM   1236 C  C   . PRO A 1 175 ? 16.01329 -37.69661 -1.06958  1.000 12.51803 ? 175 PRO A C   1 
ATOM   1237 O  O   . PRO A 1 175 ? 15.27694 -37.18648 -0.21581  1.000 13.71462 ? 175 PRO A O   1 
ATOM   1238 C  CB  . PRO A 1 175 ? 14.95133 -39.60257 -2.33913  1.000 12.37656 ? 175 PRO A CB  1 
ATOM   1239 C  CG  . PRO A 1 175 ? 15.28869 -40.17185 -3.68575  1.000 17.97499 ? 175 PRO A CG  1 
ATOM   1240 C  CD  . PRO A 1 175 ? 16.53063 -39.45950 -4.11660  1.000 13.86286 ? 175 PRO A CD  1 
ATOM   1241 N  N   . SER A 1 176 ? 17.31959 -37.87115 -0.86450  1.000 11.58640 ? 176 SER A N   1 
ATOM   1242 C  CA  . SER A 1 176 ? 17.91094 -37.61014 0.44324   1.000 10.49963 ? 176 SER A CA  1 
ATOM   1243 C  C   . SER A 1 176 ? 18.11617 -36.12908 0.73645   1.000 10.98839 ? 176 SER A C   1 
ATOM   1244 O  O   . SER A 1 176 ? 18.38508 -35.78000 1.89104   1.000 11.16613 ? 176 SER A O   1 
ATOM   1245 C  CB  . SER A 1 176 ? 19.24978 -38.34302 0.57305   1.000 14.86817 ? 176 SER A CB  1 
ATOM   1246 O  OG  . SER A 1 176 ? 20.18157 -37.87414 -0.38450  1.000 11.22435 ? 176 SER A OG  1 
ATOM   1247 N  N   . VAL A 1 177 ? 18.00379 -35.25409 -0.26127  1.000 12.96048 ? 177 VAL A N   1 
ATOM   1248 C  CA  . VAL A 1 177 ? 18.15262 -33.82063 -0.02939  1.000 13.78959 ? 177 VAL A CA  1 
ATOM   1249 C  C   . VAL A 1 177 ? 16.77152 -33.19291 0.09834   1.000 14.82717 ? 177 VAL A C   1 
ATOM   1250 O  O   . VAL A 1 177 ? 15.75213 -33.88876 0.02517   1.000 12.50474 ? 177 VAL A O   1 
ATOM   1251 C  CB  . VAL A 1 177 ? 18.96890 -33.14476 -1.14715  1.000 12.51672 ? 177 VAL A CB  1 
ATOM   1252 C  CG1 . VAL A 1 177 ? 20.37194 -33.72891 -1.20799  1.000 15.16178 ? 177 VAL A CG1 1 
ATOM   1253 C  CG2 . VAL A 1 177 ? 18.26225 -33.28568 -2.48585  1.000 11.68449 ? 177 VAL A CG2 1 
ATOM   1254 N  N   . CYS A 1 178 ? 16.72813 -31.87756 0.29200   1.000 11.85465 ? 178 CYS A N   1 
ATOM   1255 C  CA  . CYS A 1 178 ? 15.47749 -31.15212 0.50456   1.000 12.12707 ? 178 CYS A CA  1 
ATOM   1256 C  C   . CYS A 1 178 ? 15.15380 -30.38534 -0.77307  1.000 11.17540 ? 178 CYS A C   1 
ATOM   1257 O  O   . CYS A 1 178 ? 15.76953 -29.35777 -1.06716  1.000 10.33822 ? 178 CYS A O   1 
ATOM   1258 C  CB  . CYS A 1 178 ? 15.59486 -30.21977 1.70570   1.000 13.22289 ? 178 CYS A CB  1 
ATOM   1259 S  SG  . CYS A 1 178 ? 14.04434 -29.88135 2.58039   1.000 11.89443 ? 178 CYS A SG  1 
ATOM   1260 N  N   . THR A 1 179 ? 14.18760 -30.89124 -1.53447  1.000 12.46023 ? 179 THR A N   1 
ATOM   1261 C  CA  . THR A 1 179 ? 13.78297 -30.27455 -2.79193  1.000 11.62456 ? 179 THR A CA  1 
ATOM   1262 C  C   . THR A 1 179 ? 12.67624 -29.26082 -2.52808  1.000 10.93105 ? 179 THR A C   1 
ATOM   1263 O  O   . THR A 1 179 ? 11.70629 -29.56282 -1.82444  1.000 10.94472 ? 179 THR A O   1 
ATOM   1264 C  CB  . THR A 1 179 ? 13.31277 -31.33595 -3.78931  1.000 11.87099 ? 179 THR A CB  1 
ATOM   1265 O  OG1 . THR A 1 179 ? 14.30576 -32.36522 -3.89045  1.000 13.49861 ? 179 THR A OG1 1 
ATOM   1266 C  CG2 . THR A 1 179 ? 13.09962 -30.72032 -5.16005  1.000 11.76333 ? 179 THR A CG2 1 
ATOM   1267 N  N   . VAL A 1 180 ? 12.81785 -28.06616 -3.10120  1.000 12.73048 ? 180 VAL A N   1 
ATOM   1268 C  CA  . VAL A 1 180 ? 11.99622 -26.91564 -2.74212  1.000 10.83435 ? 180 VAL A CA  1 
ATOM   1269 C  C   . VAL A 1 180 ? 11.21349 -26.44964 -3.96237  1.000 9.99256  ? 180 VAL A C   1 
ATOM   1270 O  O   . VAL A 1 180 ? 11.79822 -26.18038 -5.01822  1.000 12.38645 ? 180 VAL A O   1 
ATOM   1271 C  CB  . VAL A 1 180 ? 12.85414 -25.76651 -2.18159  1.000 10.79122 ? 180 VAL A CB  1 
ATOM   1272 C  CG1 . VAL A 1 180 ? 11.98952 -24.55105 -1.88765  1.000 12.10492 ? 180 VAL A CG1 1 
ATOM   1273 C  CG2 . VAL A 1 180 ? 13.59124 -26.22020 -0.93239  1.000 11.97587 ? 180 VAL A CG2 1 
ATOM   1274 N  N   . GLY A 1 181 ? 9.89202  -26.34012 -3.80773  1.000 11.95677 ? 181 GLY A N   1 
ATOM   1275 C  CA  . GLY A 1 181 ? 9.04065  -25.73995 -4.81013  1.000 12.54095 ? 181 GLY A CA  1 
ATOM   1276 C  C   . GLY A 1 181 ? 8.75228  -24.27578 -4.50049  1.000 11.12857 ? 181 GLY A C   1 
ATOM   1277 O  O   . GLY A 1 181 ? 9.10354  -23.75248 -3.44674  1.000 10.23045 ? 181 GLY A O   1 
ATOM   1278 N  N   . ALA A 1 182 ? 8.08608  -23.61903 -5.44751  1.000 10.58961 ? 182 ALA A N   1 
ATOM   1279 C  CA  . ALA A 1 182 ? 7.84994  -22.18496 -5.37717  1.000 9.62689  ? 182 ALA A CA  1 
ATOM   1280 C  C   . ALA A 1 182 ? 6.35940  -21.87805 -5.30794  1.000 11.99615 ? 182 ALA A C   1 
ATOM   1281 O  O   . ALA A 1 182 ? 5.53210  -22.58540 -5.89104  1.000 9.98372  ? 182 ALA A O   1 
ATOM   1282 C  CB  . ALA A 1 182 ? 8.46922  -21.46368 -6.58056  1.000 10.72388 ? 182 ALA A CB  1 
ATOM   1283 N  N   . SER A 1 183 ? 6.03074  -20.80520 -4.58864  1.000 10.66439 ? 183 SER A N   1 
ATOM   1284 C  CA  . SER A 1 183 ? 4.66854  -20.30823 -4.46714  1.000 9.87380  ? 183 SER A CA  1 
ATOM   1285 C  C   . SER A 1 183 ? 4.67451  -18.79189 -4.61599  1.000 12.54870 ? 183 SER A C   1 
ATOM   1286 O  O   . SER A 1 183 ? 5.71970  -18.14410 -4.51243  1.000 13.17553 ? 183 SER A O   1 
ATOM   1287 C  CB  . SER A 1 183 ? 4.04210  -20.70389 -3.12152  1.000 12.61712 ? 183 SER A CB  1 
ATOM   1288 O  OG  . SER A 1 183 ? 4.80064  -20.19302 -2.03749  1.000 12.40029 ? 183 SER A OG  1 
ATOM   1289 N  N   . ASP A 1 184 ? 3.49527  -18.22500 -4.86574  1.000 13.65899 ? 184 ASP A N   1 
ATOM   1290 C  CA  . ASP A 1 184 ? 3.34171  -16.78100 -4.98499  1.000 14.85099 ? 184 ASP A CA  1 
ATOM   1291 C  C   . ASP A 1 184 ? 2.65407  -16.22644 -3.73895  1.000 15.95747 ? 184 ASP A C   1 
ATOM   1292 O  O   . ASP A 1 184 ? 2.30931  -16.96096 -2.80875  1.000 15.84230 ? 184 ASP A O   1 
ATOM   1293 C  CB  . ASP A 1 184 ? 2.59124  -16.40882 -6.27194  1.000 16.39065 ? 184 ASP A CB  1 
ATOM   1294 C  CG  . ASP A 1 184 ? 1.16404  -16.94492 -6.32218  1.000 20.38426 ? 184 ASP A CG  1 
ATOM   1295 O  OD1 . ASP A 1 184 ? 0.61611  -17.37007 -5.28421  1.000 21.33099 ? 184 ASP A OD1 1 
ATOM   1296 O  OD2 . ASP A 1 184 ? 0.58300  -16.93334 -7.42782  1.000 20.46908 ? 184 ASP A OD2 1 
ATOM   1297 N  N   . ARG A 1 185 ? 2.45373  -14.90641 -3.72813  1.000 17.22615 ? 185 ARG A N   1 
ATOM   1298 C  CA  . ARG A 1 185 ? 1.94287  -14.23813 -2.53676  1.000 19.61003 ? 185 ARG A CA  1 
ATOM   1299 C  C   . ARG A 1 185 ? 0.47227  -14.52848 -2.26808  1.000 18.78940 ? 185 ARG A C   1 
ATOM   1300 O  O   . ARG A 1 185 ? -0.01670 -14.18671 -1.18621  1.000 20.24178 ? 185 ARG A O   1 
ATOM   1301 C  CB  . ARG A 1 185 ? 2.15725  -12.72755 -2.64417  1.000 19.98902 ? 185 ARG A CB  1 
ATOM   1302 C  CG  . ARG A 1 185 ? 1.15008  -12.00302 -3.51839  1.000 23.71187 ? 185 ARG A CG  1 
ATOM   1303 C  CD  . ARG A 1 185 ? 1.31969  -10.49949 -3.38115  1.000 25.58087 ? 185 ARG A CD  1 
ATOM   1304 N  NE  . ARG A 1 185 ? 2.62713  -10.05603 -3.84984  1.000 29.33253 ? 185 ARG A NE  1 
ATOM   1305 C  CZ  . ARG A 1 185 ? 3.25959  -8.98102  -3.39969  1.000 29.20113 ? 185 ARG A CZ  1 
ATOM   1306 N  NH1 . ARG A 1 185 ? 2.74795  -8.23035  -2.43801  1.000 27.58713 ? 185 ARG A NH1 1 
ATOM   1307 N  NH2 . ARG A 1 185 ? 4.43900  -8.65591  -3.92160  1.000 23.87642 ? 185 ARG A NH2 1 
ATOM   1308 N  N   . TYR A 1 186 ? -0.24283 -15.14306 -3.20949  1.000 20.60918 ? 186 TYR A N   1 
ATOM   1309 C  CA  . TYR A 1 186 ? -1.62739 -15.53863 -2.99368  1.000 20.63899 ? 186 TYR A CA  1 
ATOM   1310 C  C   . TYR A 1 186 ? -1.76295 -17.02551 -2.68613  1.000 18.34518 ? 186 TYR A C   1 
ATOM   1311 O  O   . TYR A 1 186 ? -2.83732 -17.59936 -2.89499  1.000 16.46662 ? 186 TYR A O   1 
ATOM   1312 C  CB  . TYR A 1 186 ? -2.48186 -15.15943 -4.20353  1.000 18.30857 ? 186 TYR A CB  1 
ATOM   1313 C  CG  . TYR A 1 186 ? -2.59139 -13.66594 -4.41153  1.000 24.40758 ? 186 TYR A CG  1 
ATOM   1314 C  CD1 . TYR A 1 186 ? -3.47711 -12.90338 -3.65994  1.000 22.93856 ? 186 TYR A CD1 1 
ATOM   1315 C  CD2 . TYR A 1 186 ? -1.80540 -13.01732 -5.35387  1.000 23.82558 ? 186 TYR A CD2 1 
ATOM   1316 C  CE1 . TYR A 1 186 ? -3.57797 -11.53629 -3.84366  1.000 31.73695 ? 186 TYR A CE1 1 
ATOM   1317 C  CE2 . TYR A 1 186 ? -1.89921 -11.65161 -5.54540  1.000 29.15388 ? 186 TYR A CE2 1 
ATOM   1318 C  CZ  . TYR A 1 186 ? -2.78653 -10.91633 -4.78847  1.000 32.21482 ? 186 TYR A CZ  1 
ATOM   1319 O  OH  . TYR A 1 186 ? -2.87960 -9.55713  -4.97902  1.000 34.44906 ? 186 TYR A OH  1 
ATOM   1320 N  N   . ASP A 1 187 ? -0.69278 -17.65226 -2.18969  1.000 16.02257 ? 187 ASP A N   1 
ATOM   1321 C  CA  . ASP A 1 187 ? -0.68629 -19.07115 -1.82598  1.000 15.98262 ? 187 ASP A CA  1 
ATOM   1322 C  C   . ASP A 1 187 ? -1.07020 -19.95922 -3.00734  1.000 17.05850 ? 187 ASP A C   1 
ATOM   1323 O  O   . ASP A 1 187 ? -1.75012 -20.97558 -2.85178  1.000 18.32766 ? 187 ASP A O   1 
ATOM   1324 C  CB  . ASP A 1 187 ? -1.58902 -19.34121 -0.62068  1.000 15.45621 ? 187 ASP A CB  1 
ATOM   1325 C  CG  . ASP A 1 187 ? -0.93642 -18.95186 0.69132   1.000 18.02763 ? 187 ASP A CG  1 
ATOM   1326 O  OD1 . ASP A 1 187 ? 0.24103  -18.53461 0.67049   1.000 16.84922 ? 187 ASP A OD1 1 
ATOM   1327 O  OD2 . ASP A 1 187 ? -1.59883 -19.06521 1.74360   1.000 20.25167 ? 187 ASP A OD2 1 
ATOM   1328 N  N   . ARG A 1 188 ? -0.62793 -19.57356 -4.19874  1.000 15.93044 ? 188 ARG A N   1 
ATOM   1329 C  CA  . ARG A 1 188 ? -0.75413 -20.39662 -5.39064  1.000 16.95340 ? 188 ARG A CA  1 
ATOM   1330 C  C   . ARG A 1 188 ? 0.61628  -20.93777 -5.76694  1.000 16.38964 ? 188 ARG A C   1 
ATOM   1331 O  O   . ARG A 1 188 ? 1.62735  -20.24278 -5.62121  1.000 17.86612 ? 188 ARG A O   1 
ATOM   1332 C  CB  . ARG A 1 188 ? -1.33363 -19.59953 -6.56349  1.000 16.97345 ? 188 ARG A CB  1 
ATOM   1333 C  CG  . ARG A 1 188 ? -2.71857 -19.03569 -6.31295  1.000 19.88405 ? 188 ARG A CG  1 
ATOM   1334 C  CD  . ARG A 1 188 ? -3.21571 -18.21324 -7.49269  1.000 18.24046 ? 188 ARG A CD  1 
ATOM   1335 N  NE  . ARG A 1 188 ? -2.33540 -17.09051 -7.79356  1.000 24.97886 ? 188 ARG A NE  1 
ATOM   1336 C  CZ  . ARG A 1 188 ? -2.71321 -15.99505 -8.43876  1.000 19.52433 ? 188 ARG A CZ  1 
ATOM   1337 N  NH1 . ARG A 1 188 ? -3.96225 -15.82563 -8.84067  1.000 15.41811 ? 188 ARG A NH1 1 
ATOM   1338 N  NH2 . ARG A 1 188 ? -1.81710 -15.04217 -8.67995  1.000 21.59619 ? 188 ARG A NH2 1 
ATOM   1339 N  N   . ARG A 1 189 ? 0.65018  -22.18294 -6.23428  1.000 15.20358 ? 189 ARG A N   1 
ATOM   1340 C  CA  . ARG A 1 189 ? 1.88231  -22.71928 -6.79247  1.000 17.46862 ? 189 ARG A CA  1 
ATOM   1341 C  C   . ARG A 1 189 ? 2.32485  -21.84928 -7.95863  1.000 13.76154 ? 189 ARG A C   1 
ATOM   1342 O  O   . ARG A 1 189 ? 1.53316  -21.55417 -8.86002  1.000 14.30173 ? 189 ARG A O   1 
ATOM   1343 C  CB  . ARG A 1 189 ? 1.68573  -24.16411 -7.25413  1.000 13.34424 ? 189 ARG A CB  1 
ATOM   1344 C  CG  . ARG A 1 189 ? 2.90430  -24.75542 -7.95157  1.000 12.63464 ? 189 ARG A CG  1 
ATOM   1345 C  CD  . ARG A 1 189 ? 2.66324  -26.19185 -8.39152  1.000 13.70788 ? 189 ARG A CD  1 
ATOM   1346 N  NE  . ARG A 1 189 ? 1.66200  -26.28961 -9.44732  1.000 20.91500 ? 189 ARG A NE  1 
ATOM   1347 C  CZ  . ARG A 1 189 ? 1.93438  -26.25222 -10.74483 1.000 18.95700 ? 189 ARG A CZ  1 
ATOM   1348 N  NH1 . ARG A 1 189 ? 3.17215  -26.10122 -11.18755 1.000 19.69417 ? 189 ARG A NH1 1 
ATOM   1349 N  NH2 . ARG A 1 189 ? 0.94007  -26.37115 -11.62046 1.000 20.21862 ? 189 ARG A NH2 1 
ATOM   1350 N  N   . SER A 1 190 ? 3.58259  -21.41029 -7.91961  1.000 12.29150 ? 190 SER A N   1 
ATOM   1351 C  CA  . SER A 1 190 ? 4.12235  -20.60209 -9.00259  1.000 15.22789 ? 190 SER A CA  1 
ATOM   1352 C  C   . SER A 1 190 ? 3.92617  -21.31678 -10.33206 1.000 13.27857 ? 190 SER A C   1 
ATOM   1353 O  O   . SER A 1 190 ? 4.17009  -22.52033 -10.44886 1.000 17.18448 ? 190 SER A O   1 
ATOM   1354 C  CB  . SER A 1 190 ? 5.60486  -20.31620 -8.76018  1.000 14.10394 ? 190 SER A CB  1 
ATOM   1355 O  OG  . SER A 1 190 ? 5.79113  -19.60320 -7.54822  1.000 13.83806 ? 190 SER A OG  1 
ATOM   1356 N  N   . SER A 1 191 ? 3.45942  -20.56471 -11.33192 1.000 13.69054 ? 191 SER A N   1 
ATOM   1357 C  CA  . SER A 1 191 ? 3.09614  -21.15448 -12.61607 1.000 18.24385 ? 191 SER A CA  1 
ATOM   1358 C  C   . SER A 1 191 ? 4.24918  -21.90995 -13.26424 1.000 13.78975 ? 191 SER A C   1 
ATOM   1359 O  O   . SER A 1 191 ? 4.00710  -22.80163 -14.08398 1.000 17.88249 ? 191 SER A O   1 
ATOM   1360 C  CB  . SER A 1 191 ? 2.58739  -20.06516 -13.56483 1.000 17.65640 ? 191 SER A CB  1 
ATOM   1361 O  OG  . SER A 1 191 ? 3.57696  -19.07524 -13.78094 1.000 20.52438 ? 191 SER A OG  1 
ATOM   1362 N  N   . PHE A 1 192 ? 5.48996  -21.58484 -12.91139 1.000 14.55796 ? 192 PHE A N   1 
ATOM   1363 C  CA  . PHE A 1 192 ? 6.65372  -22.24533 -13.48455 1.000 11.50171 ? 192 PHE A CA  1 
ATOM   1364 C  C   . PHE A 1 192 ? 7.15681  -23.41213 -12.64648 1.000 14.07809 ? 192 PHE A C   1 
ATOM   1365 O  O   . PHE A 1 192 ? 7.92856  -24.23260 -13.15568 1.000 12.89403 ? 192 PHE A O   1 
ATOM   1366 C  CB  . PHE A 1 192 ? 7.78950  -21.23312 -13.66023 1.000 14.24869 ? 192 PHE A CB  1 
ATOM   1367 C  CG  . PHE A 1 192 ? 8.05240  -20.40742 -12.43267 1.000 14.19773 ? 192 PHE A CG  1 
ATOM   1368 C  CD1 . PHE A 1 192 ? 8.72757  -20.94629 -11.34924 1.000 11.97562 ? 192 PHE A CD1 1 
ATOM   1369 C  CD2 . PHE A 1 192 ? 7.61880  -19.09448 -12.36034 1.000 13.69063 ? 192 PHE A CD2 1 
ATOM   1370 C  CE1 . PHE A 1 192 ? 8.95972  -20.19568 -10.21726 1.000 11.40645 ? 192 PHE A CE1 1 
ATOM   1371 C  CE2 . PHE A 1 192 ? 7.85474  -18.33390 -11.23130 1.000 13.63653 ? 192 PHE A CE2 1 
ATOM   1372 C  CZ  . PHE A 1 192 ? 8.52704  -18.88524 -10.15870 1.000 13.52948 ? 192 PHE A CZ  1 
ATOM   1373 N  N   . SER A 1 193 ? 6.73706  -23.50525 -11.38678 1.000 12.28670 ? 193 SER A N   1 
ATOM   1374 C  CA  . SER A 1 193 ? 7.35700  -24.42815 -10.44546 1.000 13.18525 ? 193 SER A CA  1 
ATOM   1375 C  C   . SER A 1 193 ? 7.12042  -25.88126 -10.83797 1.000 13.18860 ? 193 SER A C   1 
ATOM   1376 O  O   . SER A 1 193 ? 6.02366  -26.26365 -11.25673 1.000 14.55704 ? 193 SER A O   1 
ATOM   1377 C  CB  . SER A 1 193 ? 6.82032  -24.17892 -9.03601  1.000 13.12222 ? 193 SER A CB  1 
ATOM   1378 O  OG  . SER A 1 193 ? 7.41384  -25.06101 -8.10048  1.000 12.32955 ? 193 SER A OG  1 
ATOM   1379 N  N   . ASN A 1 194 ? 8.16625  -26.69174 -10.69543 1.000 12.02875 ? 194 ASN A N   1 
ATOM   1380 C  CA  . ASN A 1 194 ? 8.03433  -28.12787 -10.85838 1.000 12.50639 ? 194 ASN A CA  1 
ATOM   1381 C  C   . ASN A 1 194 ? 7.24788  -28.71875 -9.68929  1.000 12.98720 ? 194 ASN A C   1 
ATOM   1382 O  O   . ASN A 1 194 ? 6.97410  -28.05701 -8.68450  1.000 12.67282 ? 194 ASN A O   1 
ATOM   1383 C  CB  . ASN A 1 194 ? 9.40895  -28.78860 -10.96578 1.000 13.86551 ? 194 ASN A CB  1 
ATOM   1384 C  CG  . ASN A 1 194 ? 10.02664 -28.62855 -12.34074 1.000 13.14389 ? 194 ASN A CG  1 
ATOM   1385 O  OD1 . ASN A 1 194 ? 9.36707  -28.18775 -13.28100 1.000 12.56175 ? 194 ASN A OD1 1 
ATOM   1386 N  ND2 . ASN A 1 194 ? 11.29500 -29.00186 -12.46873 1.000 11.73980 ? 194 ASN A ND2 1 
ATOM   1387 N  N   . TYR A 1 195 ? 6.88247  -29.98592 -9.82964  1.000 13.75699 ? 195 TYR A N   1 
ATOM   1388 C  CA  . TYR A 1 195 ? 6.09848  -30.66988 -8.81106  1.000 13.01773 ? 195 TYR A CA  1 
ATOM   1389 C  C   . TYR A 1 195 ? 6.52614  -32.13514 -8.79114  1.000 14.70091 ? 195 TYR A C   1 
ATOM   1390 O  O   . TYR A 1 195 ? 7.58272  -32.49265 -9.32060  1.000 16.24480 ? 195 TYR A O   1 
ATOM   1391 C  CB  . TYR A 1 195 ? 4.59705  -30.46428 -9.07731  1.000 14.76873 ? 195 TYR A CB  1 
ATOM   1392 C  CG  . TYR A 1 195 ? 4.17079  -30.82639 -10.48154 1.000 17.85169 ? 195 TYR A CG  1 
ATOM   1393 C  CD1 . TYR A 1 195 ? 3.82132  -32.12903 -10.80181 1.000 15.13119 ? 195 TYR A CD1 1 
ATOM   1394 C  CD2 . TYR A 1 195 ? 4.11798  -29.86693 -11.48717 1.000 20.35556 ? 195 TYR A CD2 1 
ATOM   1395 C  CE1 . TYR A 1 195 ? 3.43192  -32.47074 -12.08049 1.000 20.62256 ? 195 TYR A CE1 1 
ATOM   1396 C  CE2 . TYR A 1 195 ? 3.72930  -30.19857 -12.77139 1.000 20.83067 ? 195 TYR A CE2 1 
ATOM   1397 C  CZ  . TYR A 1 195 ? 3.38716  -31.50249 -13.06195 1.000 23.45692 ? 195 TYR A CZ  1 
ATOM   1398 O  OH  . TYR A 1 195 ? 2.99851  -31.83956 -14.33833 1.000 20.61204 ? 195 TYR A OH  1 
ATOM   1399 N  N   . GLY A 1 196 ? 5.71440  -32.98200 -8.17435  1.000 16.20132 ? 196 GLY A N   1 
ATOM   1400 C  CA  . GLY A 1 196 ? 5.99575  -34.39967 -8.07810  1.000 14.37926 ? 196 GLY A CA  1 
ATOM   1401 C  C   . GLY A 1 196 ? 6.15697  -34.85558 -6.63875  1.000 13.71261 ? 196 GLY A C   1 
ATOM   1402 O  O   . GLY A 1 196 ? 6.26703  -34.06313 -5.70501  1.000 14.20509 ? 196 GLY A O   1 
ATOM   1403 N  N   . SER A 1 197 ? 6.17010  -36.18172 -6.48573  1.000 16.48422 ? 197 SER A N   1 
ATOM   1404 C  CA  . SER A 1 197 ? 6.32445  -36.79283 -5.17168  1.000 18.97880 ? 197 SER A CA  1 
ATOM   1405 C  C   . SER A 1 197 ? 7.71858  -36.60483 -4.58931  1.000 15.57943 ? 197 SER A C   1 
ATOM   1406 O  O   . SER A 1 197 ? 7.91892  -36.90415 -3.40774  1.000 18.51088 ? 197 SER A O   1 
ATOM   1407 C  CB  . SER A 1 197 ? 5.99599  -38.28651 -5.24483  1.000 20.49639 ? 197 SER A CB  1 
ATOM   1408 O  OG  . SER A 1 197 ? 6.84277  -38.95298 -6.16612  1.000 22.39533 ? 197 SER A OG  1 
ATOM   1409 N  N   . VAL A 1 198 ? 8.68116  -36.12356 -5.37841  1.000 16.61708 ? 198 VAL A N   1 
ATOM   1410 C  CA  . VAL A 1 198 ? 10.02560 -35.90996 -4.85473  1.000 14.54644 ? 198 VAL A CA  1 
ATOM   1411 C  C   . VAL A 1 198 ? 10.14234 -34.58705 -4.10624  1.000 15.23344 ? 198 VAL A C   1 
ATOM   1412 O  O   . VAL A 1 198 ? 11.11395 -34.38504 -3.36677  1.000 15.56644 ? 198 VAL A O   1 
ATOM   1413 C  CB  . VAL A 1 198 ? 11.06376 -35.97992 -5.98863  1.000 17.81405 ? 198 VAL A CB  1 
ATOM   1414 C  CG1 . VAL A 1 198 ? 11.10797 -34.66950 -6.76054  1.000 15.18087 ? 198 VAL A CG1 1 
ATOM   1415 C  CG2 . VAL A 1 198 ? 12.43966 -36.34602 -5.44270  1.000 18.46566 ? 198 VAL A CG2 1 
ATOM   1416 N  N   . LEU A 1 199 ? 9.17814  -33.68364 -4.26668  1.000 12.91217 ? 199 LEU A N   1 
ATOM   1417 C  CA  . LEU A 1 199 ? 9.23060  -32.40684 -3.56845  1.000 14.60364 ? 199 LEU A CA  1 
ATOM   1418 C  C   . LEU A 1 199 ? 8.97833  -32.59989 -2.07849  1.000 13.09590 ? 199 LEU A C   1 
ATOM   1419 O  O   . LEU A 1 199 ? 8.09551  -33.35990 -1.67170  1.000 11.93707 ? 199 LEU A O   1 
ATOM   1420 C  CB  . LEU A 1 199 ? 8.20882  -31.42918 -4.15281  1.000 15.33220 ? 199 LEU A CB  1 
ATOM   1421 C  CG  . LEU A 1 199 ? 8.72857  -30.43031 -5.19389  1.000 15.30366 ? 199 LEU A CG  1 
ATOM   1422 C  CD1 . LEU A 1 199 ? 9.11168  -31.13243 -6.48834  1.000 15.15934 ? 199 LEU A CD1 1 
ATOM   1423 C  CD2 . LEU A 1 199 ? 7.71771  -29.31952 -5.45919  1.000 18.35351 ? 199 LEU A CD2 1 
ATOM   1424 N  N   . ASP A 1 200 ? 9.76622  -31.90295 -1.26276  1.000 11.28041 ? 200 ASP A N   1 
ATOM   1425 C  CA  . ASP A 1 200 ? 9.64464  -31.96977 0.18711   1.000 12.86343 ? 200 ASP A CA  1 
ATOM   1426 C  C   . ASP A 1 200 ? 8.85420  -30.81223 0.77469   1.000 12.26113 ? 200 ASP A C   1 
ATOM   1427 O  O   . ASP A 1 200 ? 8.14318  -31.00167 1.76798   1.000 12.73532 ? 200 ASP A O   1 
ATOM   1428 C  CB  . ASP A 1 200 ? 11.03382 -31.99229 0.83439   1.000 11.63667 ? 200 ASP A CB  1 
ATOM   1429 C  CG  . ASP A 1 200 ? 11.84946 -33.20133 0.42339   1.000 13.45531 ? 200 ASP A CG  1 
ATOM   1430 O  OD1 . ASP A 1 200 ? 11.54086 -34.31638 0.89159   1.000 14.39953 ? 200 ASP A OD1 1 
ATOM   1431 O  OD2 . ASP A 1 200 ? 12.79420 -33.03462 -0.37757  1.000 11.67002 ? 200 ASP A OD2 1 
ATOM   1432 N  N   . ILE A 1 201 ? 8.95280  -29.62351 0.18011   1.000 11.68285 ? 201 ILE A N   1 
ATOM   1433 C  CA  . ILE A 1 201 ? 8.46042  -28.40217 0.80582   1.000 12.38560 ? 201 ILE A CA  1 
ATOM   1434 C  C   . ILE A 1 201 ? 8.31434  -27.34604 -0.27918  1.000 10.57892 ? 201 ILE A C   1 
ATOM   1435 O  O   . ILE A 1 201 ? 8.87335  -27.47409 -1.37001  1.000 10.71160 ? 201 ILE A O   1 
ATOM   1436 C  CB  . ILE A 1 201 ? 9.42709  -27.94511 1.93006   1.000 9.67014  ? 201 ILE A CB  1 
ATOM   1437 C  CG1 . ILE A 1 201 ? 8.77896  -26.89174 2.83425   1.000 11.25066 ? 201 ILE A CG1 1 
ATOM   1438 C  CG2 . ILE A 1 201 ? 10.72858 -27.42837 1.33395   1.000 11.18826 ? 201 ILE A CG2 1 
ATOM   1439 C  CD1 . ILE A 1 201 ? 7.65619  -27.43005 3.69042   1.000 12.61924 ? 201 ILE A CD1 1 
ATOM   1440 N  N   . PHE A 1 202 ? 7.54653  -26.29933 0.01785   1.000 9.22453  ? 202 PHE A N   1 
ATOM   1441 C  CA  . PHE A 1 202 ? 7.39610  -25.14937 -0.85816  1.000 11.70370 ? 202 PHE A CA  1 
ATOM   1442 C  C   . PHE A 1 202 ? 7.86269  -23.88916 -0.14350  1.000 11.11526 ? 202 PHE A C   1 
ATOM   1443 O  O   . PHE A 1 202 ? 7.85457  -23.81290 1.08885   1.000 13.07057 ? 202 PHE A O   1 
ATOM   1444 C  CB  . PHE A 1 202 ? 5.94021  -24.97053 -1.30802  1.000 11.14441 ? 202 PHE A CB  1 
ATOM   1445 C  CG  . PHE A 1 202 ? 5.54758  -25.83513 -2.46820  1.000 12.18903 ? 202 PHE A CG  1 
ATOM   1446 C  CD1 . PHE A 1 202 ? 5.15401  -27.14815 -2.27028  1.000 11.31626 ? 202 PHE A CD1 1 
ATOM   1447 C  CD2 . PHE A 1 202 ? 5.56215  -25.33057 -3.75876  1.000 9.83595  ? 202 PHE A CD2 1 
ATOM   1448 C  CE1 . PHE A 1 202 ? 4.78781  -27.94429 -3.33967  1.000 12.29617 ? 202 PHE A CE1 1 
ATOM   1449 C  CE2 . PHE A 1 202 ? 5.19732  -26.12076 -4.83057  1.000 10.35777 ? 202 PHE A CE2 1 
ATOM   1450 C  CZ  . PHE A 1 202 ? 4.80909  -27.42885 -4.62035  1.000 13.34141 ? 202 PHE A CZ  1 
ATOM   1451 N  N   . GLY A 1 203 ? 8.26686  -22.89902 -0.93216  1.000 10.28334 ? 203 GLY A N   1 
ATOM   1452 C  CA  . GLY A 1 203 ? 8.69119  -21.62845 -0.39907  1.000 13.00787 ? 203 GLY A CA  1 
ATOM   1453 C  C   . GLY A 1 203 ? 8.30545  -20.48419 -1.31225  1.000 10.37241 ? 203 GLY A C   1 
ATOM   1454 O  O   . GLY A 1 203 ? 7.93469  -20.68342 -2.47322  1.000 11.78841 ? 203 GLY A O   1 
ATOM   1455 N  N   . PRO A 1 204 ? 8.37037  -19.25868 -0.79655  1.000 11.97472 ? 204 PRO A N   1 
ATOM   1456 C  CA  . PRO A 1 204 ? 8.07587  -18.08801 -1.63420  1.000 11.52085 ? 204 PRO A CA  1 
ATOM   1457 C  C   . PRO A 1 204 ? 9.07524  -17.96747 -2.77638  1.000 11.66725 ? 204 PRO A C   1 
ATOM   1458 O  O   . PRO A 1 204 ? 10.28784 -17.92205 -2.56004  1.000 11.68218 ? 204 PRO A O   1 
ATOM   1459 C  CB  . PRO A 1 204 ? 8.18982  -16.91484 -0.65288  1.000 10.26213 ? 204 PRO A CB  1 
ATOM   1460 C  CG  . PRO A 1 204 ? 7.97870  -17.52768 0.69955   1.000 13.65890 ? 204 PRO A CG  1 
ATOM   1461 C  CD  . PRO A 1 204 ? 8.59304  -18.89107 0.61094   1.000 12.38306 ? 204 PRO A CD  1 
ATOM   1462 N  N   . GLY A 1 205 ? 8.55678  -17.90740 -4.00195  1.000 12.47625 ? 205 GLY A N   1 
ATOM   1463 C  CA  . GLY A 1 205 ? 9.42227  -17.93464 -5.16500  1.000 8.77469  ? 205 GLY A CA  1 
ATOM   1464 C  C   . GLY A 1 205 ? 9.07391  -16.97452 -6.28454  1.000 12.39874 ? 205 GLY A C   1 
ATOM   1465 O  O   . GLY A 1 205 ? 9.82373  -16.86921 -7.25928  1.000 15.95952 ? 205 GLY A O   1 
ATOM   1466 N  N   . THR A 1 206 ? 7.95125  -16.27072 -6.17045  1.000 11.04920 ? 206 THR A N   1 
ATOM   1467 C  CA  . THR A 1 206 ? 7.50925  -15.32535 -7.18860  1.000 12.02364 ? 206 THR A CA  1 
ATOM   1468 C  C   . THR A 1 206 ? 7.65036  -13.90189 -6.66571  1.000 12.66145 ? 206 THR A C   1 
ATOM   1469 O  O   . THR A 1 206 ? 7.15839  -13.58498 -5.57584  1.000 14.45815 ? 206 THR A O   1 
ATOM   1470 C  CB  . THR A 1 206 ? 6.05852  -15.59023 -7.60044  1.000 13.17163 ? 206 THR A CB  1 
ATOM   1471 O  OG1 . THR A 1 206 ? 5.95084  -16.90595 -8.15616  1.000 13.70943 ? 206 THR A OG1 1 
ATOM   1472 C  CG2 . THR A 1 206 ? 5.60648  -14.57296 -8.64085  1.000 13.01638 ? 206 THR A CG2 1 
ATOM   1473 N  N   . ASP A 1 207 ? 8.31938  -13.05130 -7.44939  1.000 12.34626 ? 207 ASP A N   1 
ATOM   1474 C  CA  . ASP A 1 207 ? 8.53459  -11.63869 -7.12658  1.000 13.87471 ? 207 ASP A CA  1 
ATOM   1475 C  C   . ASP A 1 207 ? 9.20684  -11.48781 -5.75698  1.000 13.82498 ? 207 ASP A C   1 
ATOM   1476 O  O   . ASP A 1 207 ? 8.61925  -11.01489 -4.78160  1.000 14.12496 ? 207 ASP A O   1 
ATOM   1477 C  CB  . ASP A 1 207 ? 7.21665  -10.85420 -7.18793  1.000 11.61715 ? 207 ASP A CB  1 
ATOM   1478 C  CG  . ASP A 1 207 ? 6.57749  -10.89225 -8.56276  1.000 16.29701 ? 207 ASP A CG  1 
ATOM   1479 O  OD1 . ASP A 1 207 ? 7.31705  -11.00179 -9.56568  1.000 21.21773 ? 207 ASP A OD1 1 
ATOM   1480 O  OD2 . ASP A 1 207 ? 5.33543  -10.80884 -8.64333  1.000 17.19458 ? 207 ASP A OD2 1 
ATOM   1481 N  N   . ILE A 1 208 ? 10.47015 -11.90247 -5.71859  1.000 12.03412 ? 208 ILE A N   1 
ATOM   1482 C  CA  . ILE A 1 208 ? 11.26461 -11.92002 -4.49621  1.000 10.37291 ? 208 ILE A CA  1 
ATOM   1483 C  C   . ILE A 1 208 ? 12.30094 -10.80835 -4.59177  1.000 12.82110 ? 208 ILE A C   1 
ATOM   1484 O  O   . ILE A 1 208 ? 13.21641 -10.86563 -5.42239  1.000 9.94550  ? 208 ILE A O   1 
ATOM   1485 C  CB  . ILE A 1 208 ? 11.93125 -13.28289 -4.27114  1.000 11.21132 ? 208 ILE A CB  1 
ATOM   1486 C  CG1 . ILE A 1 208 ? 10.87209 -14.38249 -4.18470  1.000 8.41287  ? 208 ILE A CG1 1 
ATOM   1487 C  CG2 . ILE A 1 208 ? 12.77734 -13.25913 -3.00751  1.000 9.92501  ? 208 ILE A CG2 1 
ATOM   1488 C  CD1 . ILE A 1 208 ? 9.85214  -14.15978 -3.09004  1.000 11.93122 ? 208 ILE A CD1 1 
ATOM   1489 N  N   . LEU A 1 209 ? 12.16043 -9.79770  -3.73796  1.000 10.73684 ? 209 LEU A N   1 
ATOM   1490 C  CA  . LEU A 1 209 ? 13.11780 -8.70207  -3.68147  1.000 13.12664 ? 209 LEU A CA  1 
ATOM   1491 C  C   . LEU A 1 209 ? 14.30986 -9.10128  -2.82040  1.000 11.11791 ? 209 LEU A C   1 
ATOM   1492 O  O   . LEU A 1 209 ? 14.13880 -9.60073  -1.70400  1.000 11.25270 ? 209 LEU A O   1 
ATOM   1493 C  CB  . LEU A 1 209 ? 12.45210 -7.44614  -3.11875  1.000 12.33050 ? 209 LEU A CB  1 
ATOM   1494 C  CG  . LEU A 1 209 ? 13.31673 -6.19143  -2.97836  1.000 15.70296 ? 209 LEU A CG  1 
ATOM   1495 C  CD1 . LEU A 1 209 ? 13.66998 -5.62178  -4.34417  1.000 14.35951 ? 209 LEU A CD1 1 
ATOM   1496 C  CD2 . LEU A 1 209 ? 12.61656 -5.14829  -2.11856  1.000 12.55415 ? 209 LEU A CD2 1 
ATOM   1497 N  N   . SER A 1 210 ? 15.51435 -8.88471  -3.33923  1.000 10.31572 ? 210 SER A N   1 
ATOM   1498 C  CA  . SER A 1 210 ? 16.73833 -9.21731  -2.61755  1.000 11.73142 ? 210 SER A CA  1 
ATOM   1499 C  C   . SER A 1 210 ? 17.88051 -8.38855  -3.19669  1.000 12.14345 ? 210 SER A C   1 
ATOM   1500 O  O   . SER A 1 210 ? 17.66151 -7.46209  -3.98411  1.000 14.77401 ? 210 SER A O   1 
ATOM   1501 C  CB  . SER A 1 210 ? 17.02703 -10.72062 -2.68934  1.000 10.77587 ? 210 SER A CB  1 
ATOM   1502 O  OG  . SER A 1 210 ? 18.17738 -11.05266 -1.93123  1.000 6.76260  ? 210 SER A OG  1 
ATOM   1503 N  N   . THR A 1 211 ? 19.10597 -8.72886  -2.80761  1.000 11.79508 ? 211 THR A N   1 
ATOM   1504 C  CA  . THR A 1 211 ? 20.28107 -7.98092  -3.22248  1.000 10.65159 ? 211 THR A CA  1 
ATOM   1505 C  C   . THR A 1 211 ? 20.64736 -8.29530  -4.67073  1.000 13.18176 ? 211 THR A C   1 
ATOM   1506 O  O   . THR A 1 211 ? 20.23597 -9.30761  -5.24250  1.000 15.30117 ? 211 THR A O   1 
ATOM   1507 C  CB  . THR A 1 211 ? 21.46604 -8.28768  -2.30483  1.000 14.58752 ? 211 THR A CB  1 
ATOM   1508 O  OG1 . THR A 1 211 ? 21.51908 -9.69633  -2.03997  1.000 11.79245 ? 211 THR A OG1 1 
ATOM   1509 C  CG2 . THR A 1 211 ? 21.33238 -7.53131  -0.99044  1.000 14.03034 ? 211 THR A CG2 1 
ATOM   1510 N  N   . TRP A 1 212 ? 21.43098 -7.39913  -5.26459  1.000 12.35162 ? 212 TRP A N   1 
ATOM   1511 C  CA  . TRP A 1 212 ? 21.90425 -7.57123  -6.62918  1.000 12.23901 ? 212 TRP A CA  1 
ATOM   1512 C  C   . TRP A 1 212 ? 23.28327 -6.93468  -6.73289  1.000 13.95209 ? 212 TRP A C   1 
ATOM   1513 O  O   . TRP A 1 212 ? 23.70361 -6.17435  -5.85760  1.000 12.05305 ? 212 TRP A O   1 
ATOM   1514 C  CB  . TRP A 1 212 ? 20.91783 -6.96848  -7.63884  1.000 12.37035 ? 212 TRP A CB  1 
ATOM   1515 C  CG  . TRP A 1 212 ? 21.09085 -7.47759  -9.03829  1.000 12.98669 ? 212 TRP A CG  1 
ATOM   1516 C  CD1 . TRP A 1 212 ? 21.68559 -6.82543  -10.07764 1.000 14.58561 ? 212 TRP A CD1 1 
ATOM   1517 C  CD2 . TRP A 1 212 ? 20.67035 -8.75014  -9.55073  1.000 12.68619 ? 212 TRP A CD2 1 
ATOM   1518 N  NE1 . TRP A 1 212 ? 21.65962 -7.60899  -11.20627 1.000 12.61812 ? 212 TRP A NE1 1 
ATOM   1519 C  CE2 . TRP A 1 212 ? 21.04209 -8.79552  -10.90940 1.000 14.53953 ? 212 TRP A CE2 1 
ATOM   1520 C  CE3 . TRP A 1 212 ? 20.01436 -9.85347  -8.99385  1.000 12.77772 ? 212 TRP A CE3 1 
ATOM   1521 C  CZ2 . TRP A 1 212 ? 20.78101 -9.89977  -11.71924 1.000 13.85272 ? 212 TRP A CZ2 1 
ATOM   1522 C  CZ3 . TRP A 1 212 ? 19.75591 -10.95026 -9.80139  1.000 12.46993 ? 212 TRP A CZ3 1 
ATOM   1523 C  CH2 . TRP A 1 212 ? 20.13890 -10.96429 -11.14804 1.000 14.06746 ? 212 TRP A CH2 1 
ATOM   1524 N  N   . ILE A 1 213 ? 23.99882 -7.26625  -7.81089  1.000 10.81680 ? 213 ILE A N   1 
ATOM   1525 C  CA  . ILE A 1 213 ? 25.35665 -6.75066  -7.96977  1.000 14.33241 ? 213 ILE A CA  1 
ATOM   1526 C  C   . ILE A 1 213 ? 25.31984 -5.24415  -8.21146  1.000 17.78075 ? 213 ILE A C   1 
ATOM   1527 O  O   . ILE A 1 213 ? 24.29852 -4.66334  -8.60163  1.000 16.78067 ? 213 ILE A O   1 
ATOM   1528 C  CB  . ILE A 1 213 ? 26.10055 -7.47737  -9.10197  1.000 13.60384 ? 213 ILE A CB  1 
ATOM   1529 C  CG1 . ILE A 1 213 ? 25.33659 -7.33676  -10.41838 1.000 19.17556 ? 213 ILE A CG1 1 
ATOM   1530 C  CG2 . ILE A 1 213 ? 26.31183 -8.94039  -8.74503  1.000 13.82556 ? 213 ILE A CG2 1 
ATOM   1531 C  CD1 . ILE A 1 213 ? 26.03527 -7.97223  -11.59955 1.000 21.32349 ? 213 ILE A CD1 1 
ATOM   1532 N  N   . GLY A 1 214 ? 26.46224 -4.60359  -7.97763  1.000 15.27392 ? 214 GLY A N   1 
ATOM   1533 C  CA  . GLY A 1 214 ? 26.52989 -3.15810  -8.03789  1.000 14.92411 ? 214 GLY A CA  1 
ATOM   1534 C  C   . GLY A 1 214 ? 25.95391 -2.45849  -6.83177  1.000 14.95750 ? 214 GLY A C   1 
ATOM   1535 O  O   . GLY A 1 214 ? 25.63229 -1.26870  -6.91255  1.000 22.16674 ? 214 GLY A O   1 
ATOM   1536 N  N   . GLY A 1 215 ? 25.81399 -3.16229  -5.71066  1.000 13.15576 ? 215 GLY A N   1 
ATOM   1537 C  CA  . GLY A 1 215 ? 25.22855 -2.57673  -4.51811  1.000 13.81627 ? 215 GLY A CA  1 
ATOM   1538 C  C   . GLY A 1 215 ? 23.77138 -2.20124  -4.66165  1.000 15.70219 ? 215 GLY A C   1 
ATOM   1539 O  O   . GLY A 1 215 ? 23.31829 -1.25301  -4.01430  1.000 16.00276 ? 215 GLY A O   1 
ATOM   1540 N  N   . SER A 1 216 ? 23.02002 -2.92877  -5.48351  1.000 13.86299 ? 216 SER A N   1 
ATOM   1541 C  CA  . SER A 1 216 ? 21.63374 -2.60591  -5.79549  1.000 15.05195 ? 216 SER A CA  1 
ATOM   1542 C  C   . SER A 1 216 ? 20.70125 -3.71824  -5.31011  1.000 15.55860 ? 216 SER A C   1 
ATOM   1543 O  O   . SER A 1 216 ? 21.11308 -4.65003  -4.61262  1.000 15.36036 ? 216 SER A O   1 
ATOM   1544 C  CB  . SER A 1 216 ? 21.47630 -2.36529  -7.29934  1.000 14.68757 ? 216 SER A CB  1 
ATOM   1545 O  OG  . SER A 1 216 ? 21.83536 -3.52267  -8.03410  1.000 16.70199 ? 216 SER A OG  1 
ATOM   1546 N  N   . THR A 1 217 ? 19.42567 -3.59483  -5.68028  1.000 15.66821 ? 217 THR A N   1 
ATOM   1547 C  CA  . THR A 1 217 ? 18.40262 -4.58842  -5.38806  1.000 13.98053 ? 217 THR A CA  1 
ATOM   1548 C  C   . THR A 1 217 ? 17.50397 -4.73879  -6.60736  1.000 13.55771 ? 217 THR A C   1 
ATOM   1549 O  O   . THR A 1 217 ? 17.42705 -3.84788  -7.45709  1.000 14.81596 ? 217 THR A O   1 
ATOM   1550 C  CB  . THR A 1 217 ? 17.54737 -4.20245  -4.17120  1.000 16.30493 ? 217 THR A CB  1 
ATOM   1551 O  OG1 . THR A 1 217 ? 16.89389 -2.95174  -4.42176  1.000 20.88668 ? 217 THR A OG1 1 
ATOM   1552 C  CG2 . THR A 1 217 ? 18.39737 -4.09080  -2.91070  1.000 14.79424 ? 217 THR A CG2 1 
ATOM   1553 N  N   . ARG A 1 218 ? 16.81871 -5.87727  -6.68345  1.000 15.37298 ? 218 ARG A N   1 
ATOM   1554 C  CA  . ARG A 1 218 ? 15.80165 -6.10045  -7.70600  1.000 15.63963 ? 218 ARG A CA  1 
ATOM   1555 C  C   . ARG A 1 218 ? 14.98108 -7.32036  -7.30972  1.000 13.17158 ? 218 ARG A C   1 
ATOM   1556 O  O   . ARG A 1 218 ? 15.33893 -8.06440  -6.39283  1.000 14.19936 ? 218 ARG A O   1 
ATOM   1557 C  CB  . ARG A 1 218 ? 16.40955 -6.28221  -9.10086  1.000 13.84822 ? 218 ARG A CB  1 
ATOM   1558 C  CG  . ARG A 1 218 ? 17.15072 -7.58794  -9.31105  1.000 14.86858 ? 218 ARG A CG  1 
ATOM   1559 C  CD  . ARG A 1 218 ? 17.58760 -7.71969  -10.76163 1.000 15.80714 ? 218 ARG A CD  1 
ATOM   1560 N  NE  . ARG A 1 218 ? 18.41014 -6.59061  -11.18134 1.000 17.08294 ? 218 ARG A NE  1 
ATOM   1561 C  CZ  . ARG A 1 218 ? 18.86078 -6.40630  -12.41483 1.000 15.56135 ? 218 ARG A CZ  1 
ATOM   1562 N  NH1 . ARG A 1 218 ? 18.58018 -7.25757  -13.38792 1.000 16.22485 ? 218 ARG A NH1 1 
ATOM   1563 N  NH2 . ARG A 1 218 ? 19.61160 -5.34047  -12.67876 1.000 14.13199 ? 218 ARG A NH2 1 
ATOM   1564 N  N   . SER A 1 219 ? 13.87234 -7.51562  -8.01981  1.000 13.36945 ? 219 SER A N   1 
ATOM   1565 C  CA  . SER A 1 219 ? 12.93608 -8.59932  -7.75482  1.000 14.84888 ? 219 SER A CA  1 
ATOM   1566 C  C   . SER A 1 219 ? 12.86714 -9.52052  -8.96426  1.000 11.68562 ? 219 SER A C   1 
ATOM   1567 O  O   . SER A 1 219 ? 12.63578 -9.06027  -10.08731 1.000 15.01798 ? 219 SER A O   1 
ATOM   1568 C  CB  . SER A 1 219 ? 11.54475 -8.04863  -7.42558  1.000 15.49206 ? 219 SER A CB  1 
ATOM   1569 O  OG  . SER A 1 219 ? 10.58431 -9.08724  -7.35228  1.000 22.42405 ? 219 SER A OG  1 
ATOM   1570 N  N   . ILE A 1 220 ? 13.07222 -10.81807 -8.73260  1.000 10.87826 ? 220 ILE A N   1 
ATOM   1571 C  CA  . ILE A 1 220 ? 12.97621 -11.83777 -9.77025  1.000 12.90755 ? 220 ILE A CA  1 
ATOM   1572 C  C   . ILE A 1 220 ? 12.21044 -13.02919 -9.20834  1.000 11.40356 ? 220 ILE A C   1 
ATOM   1573 O  O   . ILE A 1 220 ? 11.88950 -13.08835 -8.02011  1.000 12.92707 ? 220 ILE A O   1 
ATOM   1574 C  CB  . ILE A 1 220 ? 14.35858 -12.28352 -10.29393 1.000 16.29757 ? 220 ILE A CB  1 
ATOM   1575 C  CG1 . ILE A 1 220 ? 15.26028 -12.71143 -9.13505  1.000 13.88362 ? 220 ILE A CG1 1 
ATOM   1576 C  CG2 . ILE A 1 220 ? 15.00832 -11.17544 -11.11185 1.000 14.79856 ? 220 ILE A CG2 1 
ATOM   1577 C  CD1 . ILE A 1 220 ? 16.63767 -13.16424 -9.57160  1.000 13.03543 ? 220 ILE A CD1 1 
ATOM   1578 N  N   . SER A 1 221 ? 11.92403 -13.99074 -10.08373 1.000 12.82063 ? 221 SER A N   1 
ATOM   1579 C  CA  . SER A 1 221 ? 11.11316 -15.14690 -9.73446  1.000 13.74328 ? 221 SER A CA  1 
ATOM   1580 C  C   . SER A 1 221 ? 11.81856 -16.43074 -10.14695 1.000 15.32142 ? 221 SER A C   1 
ATOM   1581 O  O   . SER A 1 221 ? 12.66306 -16.43651 -11.04694 1.000 15.60496 ? 221 SER A O   1 
ATOM   1582 C  CB  . SER A 1 221 ? 9.73199  -15.07971 -10.39966 1.000 12.76795 ? 221 SER A CB  1 
ATOM   1583 O  OG  . SER A 1 221 ? 9.08274  -13.85768 -10.09764 1.000 13.91981 ? 221 SER A OG  1 
ATOM   1584 N  N   . GLY A 1 222 ? 11.45757 -17.51392 -9.48424  1.000 13.94906 ? 222 GLY A N   1 
ATOM   1585 C  CA  . GLY A 1 222 ? 12.01033 -18.82322 -9.76802  1.000 10.54029 ? 222 GLY A CA  1 
ATOM   1586 C  C   . GLY A 1 222 ? 12.08518 -19.66115 -8.51020  1.000 12.17166 ? 222 GLY A C   1 
ATOM   1587 O  O   . GLY A 1 222 ? 12.06171 -19.16440 -7.38614  1.000 13.20200 ? 222 GLY A O   1 
ATOM   1588 N  N   . THR A 1 223 ? 12.17160 -20.97995 -8.70787  1.000 15.17931 ? 223 THR A N   1 
ATOM   1589 C  CA  . THR A 1 223 ? 12.47124 -21.86849 -7.59096  1.000 11.51574 ? 223 THR A CA  1 
ATOM   1590 C  C   . THR A 1 223 ? 13.86408 -21.61460 -7.03535  1.000 11.97922 ? 223 THR A C   1 
ATOM   1591 O  O   . THR A 1 223 ? 14.17122 -22.06309 -5.92549  1.000 11.09689 ? 223 THR A O   1 
ATOM   1592 C  CB  . THR A 1 223 ? 12.34163 -23.33411 -8.01297  1.000 9.67084  ? 223 THR A CB  1 
ATOM   1593 O  OG1 . THR A 1 223 ? 13.17279 -23.58359 -9.15370  1.000 11.50021 ? 223 THR A OG1 1 
ATOM   1594 C  CG2 . THR A 1 223 ? 10.89723 -23.66796 -8.35481  1.000 11.06305 ? 223 THR A CG2 1 
ATOM   1595 N  N   . SER A 1 224 ? 14.71297 -20.91098 -7.78977  1.000 13.20714 ? 224 SER A N   1 
ATOM   1596 C  CA  . SER A 1 224 ? 15.99202 -20.45367 -7.26463  1.000 12.34852 ? 224 SER A CA  1 
ATOM   1597 C  C   . SER A 1 224 ? 15.81789 -19.42852 -6.15476  1.000 13.66319 ? 224 SER A C   1 
ATOM   1598 O  O   . SER A 1 224 ? 16.76362 -19.18149 -5.39906  1.000 10.93265 ? 224 SER A O   1 
ATOM   1599 C  CB  . SER A 1 224 ? 16.83855 -19.85480 -8.38742  1.000 14.82946 ? 224 SER A CB  1 
ATOM   1600 O  OG  . SER A 1 224 ? 17.14348 -20.82137 -9.37656  1.000 19.44522 ? 224 SER A OG  1 
ATOM   1601 N  N   . MET A 1 225 ? 14.64166 -18.81042 -6.05562  1.000 10.58071 ? 225 MET A N   1 
ATOM   1602 C  CA  . MET A 1 225 ? 14.35715 -17.87615 -4.97524  1.000 10.14207 ? 225 MET A CA  1 
ATOM   1603 C  C   . MET A 1 225 ? 13.71246 -18.55149 -3.77526  1.000 10.99474 ? 225 MET A C   1 
ATOM   1604 O  O   . MET A 1 225 ? 13.86681 -18.07136 -2.64633  1.000 10.23701 ? 225 MET A O   1 
ATOM   1605 C  CB  . MET A 1 225 ? 13.44477 -16.74926 -5.46970  1.000 11.36129 ? 225 MET A CB  1 
ATOM   1606 C  CG  . MET A 1 225 ? 14.14143 -15.67620 -6.29455  1.000 10.47302 ? 225 MET A CG  1 
ATOM   1607 S  SD  . MET A 1 225 ? 14.80151 -16.27793 -7.86103  1.000 14.41092 ? 225 MET A SD  1 
ATOM   1608 C  CE  . MET A 1 225 ? 16.55876 -16.29581 -7.51088  1.000 9.92616  ? 225 MET A CE  1 
ATOM   1609 N  N   . ALA A 1 226 ? 12.99030 -19.65225 -3.99287  1.000 9.61705  ? 226 ALA A N   1 
ATOM   1610 C  CA  . ALA A 1 226 ? 12.34926 -20.33985 -2.87899  1.000 9.86264  ? 226 ALA A CA  1 
ATOM   1611 C  C   . ALA A 1 226 ? 13.34778 -21.16526 -2.07895  1.000 10.83325 ? 226 ALA A C   1 
ATOM   1612 O  O   . ALA A 1 226 ? 13.18376 -21.32558 -0.86406  1.000 10.74157 ? 226 ALA A O   1 
ATOM   1613 C  CB  . ALA A 1 226 ? 11.21203 -21.22212 -3.39100  1.000 8.82881  ? 226 ALA A CB  1 
ATOM   1614 N  N   . THR A 1 227 ? 14.38572 -21.68408 -2.73505  1.000 10.52830 ? 227 THR A N   1 
ATOM   1615 C  CA  . THR A 1 227 ? 15.37999 -22.49831 -2.03769  1.000 9.68670  ? 227 THR A CA  1 
ATOM   1616 C  C   . THR A 1 227 ? 16.09956 -21.74084 -0.92527  1.000 9.34639  ? 227 THR A C   1 
ATOM   1617 O  O   . THR A 1 227 ? 16.20064 -22.28509 0.18804   1.000 9.81312  ? 227 THR A O   1 
ATOM   1618 C  CB  . THR A 1 227 ? 16.36676 -23.08352 -3.05619  1.000 11.97397 ? 227 THR A CB  1 
ATOM   1619 O  OG1 . THR A 1 227 ? 15.65531 -23.90422 -3.99284  1.000 12.90379 ? 227 THR A OG1 1 
ATOM   1620 C  CG2 . THR A 1 227 ? 17.42654 -23.92434 -2.35941  1.000 9.64315  ? 227 THR A CG2 1 
ATOM   1621 N  N   . PRO A 1 228 ? 16.61179 -20.51867 -1.12802  1.000 10.31048 ? 228 PRO A N   1 
ATOM   1622 C  CA  . PRO A 1 228 ? 17.27230 -19.81972 -0.01095  1.000 12.07296 ? 228 PRO A CA  1 
ATOM   1623 C  C   . PRO A 1 228 ? 16.34453 -19.50422 1.14857   1.000 10.00284 ? 228 PRO A C   1 
ATOM   1624 O  O   . PRO A 1 228 ? 16.82959 -19.30547 2.26949   1.000 9.69860  ? 228 PRO A O   1 
ATOM   1625 C  CB  . PRO A 1 228 ? 17.80989 -18.53816 -0.66387  1.000 9.50731  ? 228 PRO A CB  1 
ATOM   1626 C  CG  . PRO A 1 228 ? 16.98922 -18.35227 -1.88168  1.000 9.76241  ? 228 PRO A CG  1 
ATOM   1627 C  CD  . PRO A 1 228 ? 16.70550 -19.73384 -2.37233  1.000 9.29609  ? 228 PRO A CD  1 
ATOM   1628 N  N   . HIS A 1 229 ? 15.03080 -19.43678 0.91674   1.000 10.16038 ? 229 HIS A N   1 
ATOM   1629 C  CA  . HIS A 1 229 ? 14.09389 -19.31665 2.02913   1.000 11.06918 ? 229 HIS A CA  1 
ATOM   1630 C  C   . HIS A 1 229 ? 14.17070 -20.53627 2.93875   1.000 9.89279  ? 229 HIS A C   1 
ATOM   1631 O  O   . HIS A 1 229 ? 14.18875 -20.40499 4.16831   1.000 10.61032 ? 229 HIS A O   1 
ATOM   1632 C  CB  . HIS A 1 229 ? 12.66851 -19.13249 1.50607   1.000 10.66176 ? 229 HIS A CB  1 
ATOM   1633 C  CG  . HIS A 1 229 ? 12.34313 -17.72639 1.10713   1.000 11.33604 ? 229 HIS A CG  1 
ATOM   1634 N  ND1 . HIS A 1 229 ? 12.41614 -17.28395 -0.19620  1.000 11.44153 ? 229 HIS A ND1 1 
ATOM   1635 C  CD2 . HIS A 1 229 ? 11.93705 -16.66396 1.84214   1.000 13.26323 ? 229 HIS A CD2 1 
ATOM   1636 C  CE1 . HIS A 1 229 ? 12.06991 -16.00952 -0.24660  1.000 11.50095 ? 229 HIS A CE1 1 
ATOM   1637 N  NE2 . HIS A 1 229 ? 11.77556 -15.60900 0.97706   1.000 12.27514 ? 229 HIS A NE2 1 
ATOM   1638 N  N   . VAL A 1 230 ? 14.22391 -21.73344 2.34963   1.000 8.83062  ? 230 VAL A N   1 
ATOM   1639 C  CA  . VAL A 1 230 ? 14.30849 -22.95446 3.14462   1.000 11.17955 ? 230 VAL A CA  1 
ATOM   1640 C  C   . VAL A 1 230 ? 15.70346 -23.11074 3.73838   1.000 9.43913  ? 230 VAL A C   1 
ATOM   1641 O  O   . VAL A 1 230 ? 15.86016 -23.55595 4.88237   1.000 12.31792 ? 230 VAL A O   1 
ATOM   1642 C  CB  . VAL A 1 230 ? 13.90942 -24.17020 2.28775   1.000 13.58030 ? 230 VAL A CB  1 
ATOM   1643 C  CG1 . VAL A 1 230 ? 14.10282 -25.46538 3.06436   1.000 10.44991 ? 230 VAL A CG1 1 
ATOM   1644 C  CG2 . VAL A 1 230 ? 12.46709 -24.03404 1.82197   1.000 8.87880  ? 230 VAL A CG2 1 
ATOM   1645 N  N   . ALA A 1 231 ? 16.73731 -22.74336 2.97700   1.000 8.02585  ? 231 ALA A N   1 
ATOM   1646 C  CA  . ALA A 1 231 ? 18.09932 -22.81733 3.49609   1.000 10.77017 ? 231 ALA A CA  1 
ATOM   1647 C  C   . ALA A 1 231 ? 18.29076 -21.87471 4.67738   1.000 8.52766  ? 231 ALA A C   1 
ATOM   1648 O  O   . ALA A 1 231 ? 18.88686 -22.25257 5.69309   1.000 11.38462 ? 231 ALA A O   1 
ATOM   1649 C  CB  . ALA A 1 231 ? 19.10196 -22.50066 2.38661   1.000 8.71758  ? 231 ALA A CB  1 
ATOM   1650 N  N   . GLY A 1 232 ? 17.78862 -20.64373 4.56467   1.000 7.27912  ? 232 GLY A N   1 
ATOM   1651 C  CA  . GLY A 1 232 ? 17.89627 -19.71020 5.67337   1.000 9.20173  ? 232 GLY A CA  1 
ATOM   1652 C  C   . GLY A 1 232 ? 17.08428 -20.14111 6.87938   1.000 9.57106  ? 232 GLY A C   1 
ATOM   1653 O  O   . GLY A 1 232 ? 17.51268 -19.96576 8.02281   1.000 8.46905  ? 232 GLY A O   1 
ATOM   1654 N  N   . LEU A 1 233 ? 15.89996 -20.71180 6.64014   1.000 8.41117  ? 233 LEU A N   1 
ATOM   1655 C  CA  . LEU A 1 233 ? 15.06838 -21.19127 7.73986   1.000 9.84293  ? 233 LEU A CA  1 
ATOM   1656 C  C   . LEU A 1 233 ? 15.74544 -22.33504 8.48188   1.000 12.02661 ? 233 LEU A C   1 
ATOM   1657 O  O   . LEU A 1 233 ? 15.65672 -22.42680 9.71202   1.000 11.45346 ? 233 LEU A O   1 
ATOM   1658 C  CB  . LEU A 1 233 ? 13.70321 -21.63285 7.21163   1.000 9.58247  ? 233 LEU A CB  1 
ATOM   1659 C  CG  . LEU A 1 233 ? 12.73506 -22.19814 8.25169   1.000 14.29947 ? 233 LEU A CG  1 
ATOM   1660 C  CD1 . LEU A 1 233 ? 12.39753 -21.13451 9.28238   1.000 12.07338 ? 233 LEU A CD1 1 
ATOM   1661 C  CD2 . LEU A 1 233 ? 11.47071 -22.74434 7.60067   1.000 14.09236 ? 233 LEU A CD2 1 
ATOM   1662 N  N   . ALA A 1 234 ? 16.42308 -23.22024 7.74748   1.000 9.50988  ? 234 ALA A N   1 
ATOM   1663 C  CA  . ALA A 1 234 ? 17.14260 -24.31984 8.38083   1.000 12.97788 ? 234 ALA A CA  1 
ATOM   1664 C  C   . ALA A 1 234 ? 18.22571 -23.79539 9.31482   1.000 11.42233 ? 234 ALA A C   1 
ATOM   1665 O  O   . ALA A 1 234 ? 18.29523 -24.18740 10.48428  1.000 10.76611 ? 234 ALA A O   1 
ATOM   1666 C  CB  . ALA A 1 234 ? 17.74143 -25.23583 7.31299   1.000 10.27570 ? 234 ALA A CB  1 
ATOM   1667 N  N   . ALA A 1 235 ? 19.07574 -22.89424 8.81427   1.000 9.90663  ? 235 ALA A N   1 
ATOM   1668 C  CA  . ALA A 1 235 ? 20.10757 -22.29393 9.65534   1.000 11.59394 ? 235 ALA A CA  1 
ATOM   1669 C  C   . ALA A 1 235 ? 19.49675 -21.56225 10.84384  1.000 11.64473 ? 235 ALA A C   1 
ATOM   1670 O  O   . ALA A 1 235 ? 20.07392 -21.54647 11.93752  1.000 10.72021 ? 235 ALA A O   1 
ATOM   1671 C  CB  . ALA A 1 235 ? 20.96998 -21.34154 8.82704   1.000 7.56809  ? 235 ALA A CB  1 
ATOM   1672 N  N   . TYR A 1 236 ? 18.33054 -20.94465 10.64514  1.000 8.84085  ? 236 TYR A N   1 
ATOM   1673 C  CA  . TYR A 1 236 ? 17.64478 -20.27564 11.74514  1.000 11.95702 ? 236 TYR A CA  1 
ATOM   1674 C  C   . TYR A 1 236 ? 17.17399 -21.27880 12.79095  1.000 13.45756 ? 236 TYR A C   1 
ATOM   1675 O  O   . TYR A 1 236 ? 17.31180 -21.04143 13.99651  1.000 14.63834 ? 236 TYR A O   1 
ATOM   1676 C  CB  . TYR A 1 236 ? 16.47105 -19.46258 11.19604  1.000 11.15426 ? 236 TYR A CB  1 
ATOM   1677 C  CG  . TYR A 1 236 ? 15.49600 -18.95036 12.23477  1.000 13.35981 ? 236 TYR A CG  1 
ATOM   1678 C  CD1 . TYR A 1 236 ? 15.72520 -17.75418 12.90274  1.000 12.60098 ? 236 TYR A CD1 1 
ATOM   1679 C  CD2 . TYR A 1 236 ? 14.33203 -19.65079 12.52696  1.000 12.60766 ? 236 TYR A CD2 1 
ATOM   1680 C  CE1 . TYR A 1 236 ? 14.83089 -17.27962 13.84442  1.000 13.64963 ? 236 TYR A CE1 1 
ATOM   1681 C  CE2 . TYR A 1 236 ? 13.43349 -19.18481 13.46691  1.000 15.03708 ? 236 TYR A CE2 1 
ATOM   1682 C  CZ  . TYR A 1 236 ? 13.68710 -17.99907 14.12202  1.000 16.00824 ? 236 TYR A CZ  1 
ATOM   1683 O  OH  . TYR A 1 236 ? 12.79198 -17.53269 15.05688  1.000 14.47673 ? 236 TYR A OH  1 
ATOM   1684 N  N   . LEU A 1 237 ? 16.62822 -22.41393 12.34723  1.000 9.68590  ? 237 LEU A N   1 
ATOM   1685 C  CA  . LEU A 1 237 ? 16.11359 -23.40958 13.28164  1.000 12.21099 ? 237 LEU A CA  1 
ATOM   1686 C  C   . LEU A 1 237 ? 17.23343 -24.16944 13.98504  1.000 13.91320 ? 237 LEU A C   1 
ATOM   1687 O  O   . LEU A 1 237 ? 17.07260 -24.56783 15.14386  1.000 17.79289 ? 237 LEU A O   1 
ATOM   1688 C  CB  . LEU A 1 237 ? 15.18851 -24.38167 12.54751  1.000 13.15387 ? 237 LEU A CB  1 
ATOM   1689 C  CG  . LEU A 1 237 ? 13.84676 -23.82104 12.06874  1.000 12.78244 ? 237 LEU A CG  1 
ATOM   1690 C  CD1 . LEU A 1 237 ? 13.13991 -24.81665 11.16275  1.000 15.52075 ? 237 LEU A CD1 1 
ATOM   1691 C  CD2 . LEU A 1 237 ? 12.96686 -23.45798 13.25567  1.000 10.27036 ? 237 LEU A CD2 1 
ATOM   1692 N  N   . MET A 1 238 ? 18.36636 -24.38476 13.31171  1.000 14.20795 ? 238 MET A N   1 
ATOM   1693 C  CA  . MET A 1 238 ? 19.46075 -25.12458 13.93479  1.000 13.97890 ? 238 MET A CA  1 
ATOM   1694 C  C   . MET A 1 238 ? 20.14043 -24.29853 15.02022  1.000 15.04443 ? 238 MET A C   1 
ATOM   1695 O  O   . MET A 1 238 ? 20.57885 -24.84373 16.04025  1.000 14.75558 ? 238 MET A O   1 
ATOM   1696 C  CB  . MET A 1 238 ? 20.46595 -25.56087 12.87082  1.000 14.71797 ? 238 MET A CB  1 
ATOM   1697 C  CG  . MET A 1 238 ? 19.84879 -26.42142 11.78068  1.000 17.54065 ? 238 MET A CG  1 
ATOM   1698 S  SD  . MET A 1 238 ? 20.94623 -26.72020 10.38159  1.000 20.64923 ? 238 MET A SD  1 
ATOM   1699 C  CE  . MET A 1 238 ? 22.21995 -27.73071 11.14229  1.000 17.20583 ? 238 MET A CE  1 
ATOM   1700 N  N   . THR A 1 239 ? 20.23980 -22.98253 14.81699  1.000 12.84191 ? 239 THR A N   1 
ATOM   1701 C  CA  . THR A 1 239 ? 20.75095 -22.10708 15.86603  1.000 16.98118 ? 239 THR A CA  1 
ATOM   1702 C  C   . THR A 1 239 ? 19.88975 -22.18599 17.12243  1.000 14.90941 ? 239 THR A C   1 
ATOM   1703 O  O   . THR A 1 239 ? 20.41212 -22.10625 18.24086  1.000 16.29872 ? 239 THR A O   1 
ATOM   1704 C  CB  . THR A 1 239 ? 20.83333 -20.66992 15.34160  1.000 14.70264 ? 239 THR A CB  1 
ATOM   1705 O  OG1 . THR A 1 239 ? 21.88015 -20.57922 14.36526  1.000 15.04742 ? 239 THR A OG1 1 
ATOM   1706 C  CG2 . THR A 1 239 ? 21.10900 -19.68102 16.46719  1.000 18.09311 ? 239 THR A CG2 1 
ATOM   1707 N  N   . LEU A 1 240 ? 18.57988 -22.37766 16.96121  1.000 17.13341 ? 240 LEU A N   1 
ATOM   1708 C  CA  . LEU A 1 240 ? 17.65914 -22.51784 18.08436  1.000 19.52345 ? 240 LEU A CA  1 
ATOM   1709 C  C   . LEU A 1 240 ? 17.72312 -23.88954 18.74389  1.000 16.87749 ? 240 LEU A C   1 
ATOM   1710 O  O   . LEU A 1 240 ? 17.04054 -24.10276 19.75185  1.000 18.92398 ? 240 LEU A O   1 
ATOM   1711 C  CB  . LEU A 1 240 ? 16.21914 -22.24868 17.62740  1.000 18.41218 ? 240 LEU A CB  1 
ATOM   1712 C  CG  . LEU A 1 240 ? 15.69582 -20.80903 17.63324  1.000 21.67672 ? 240 LEU A CG  1 
ATOM   1713 C  CD1 . LEU A 1 240 ? 16.64542 -19.88437 16.91326  1.000 21.12815 ? 240 LEU A CD1 1 
ATOM   1714 C  CD2 . LEU A 1 240 ? 14.30855 -20.73530 17.00641  1.000 16.13114 ? 240 LEU A CD2 1 
ATOM   1715 N  N   . GLY A 1 241 ? 18.51572 -24.81728 18.20975  1.000 17.52253 ? 241 GLY A N   1 
ATOM   1716 C  CA  . GLY A 1 241 ? 18.55057 -26.16518 18.73857  1.000 15.26133 ? 241 GLY A CA  1 
ATOM   1717 C  C   . GLY A 1 241 ? 17.31910 -26.99031 18.45188  1.000 16.56779 ? 241 GLY A C   1 
ATOM   1718 O  O   . GLY A 1 241 ? 17.14886 -28.05613 19.05234  1.000 18.06005 ? 241 GLY A O   1 
ATOM   1719 N  N   . LYS A 1 242 ? 16.45239 -26.52952 17.54786  1.000 18.06480 ? 242 LYS A N   1 
ATOM   1720 C  CA  . LYS A 1 242 ? 15.21959 -27.25228 17.26095  1.000 17.13356 ? 242 LYS A CA  1 
ATOM   1721 C  C   . LYS A 1 242 ? 15.47908 -28.52696 16.46728  1.000 18.32297 ? 242 LYS A C   1 
ATOM   1722 O  O   . LYS A 1 242 ? 14.78801 -29.53085 16.67226  1.000 16.58843 ? 242 LYS A O   1 
ATOM   1723 C  CB  . LYS A 1 242 ? 14.24990 -26.34612 16.50053  1.000 17.79665 ? 242 LYS A CB  1 
ATOM   1724 C  CG  . LYS A 1 242 ? 13.83275 -25.08628 17.24994  1.000 17.74250 ? 242 LYS A CG  1 
ATOM   1725 C  CD  . LYS A 1 242 ? 12.47885 -25.26624 17.92317  1.000 25.14516 ? 242 LYS A CD  1 
ATOM   1726 C  CE  . LYS A 1 242 ? 11.86355 -23.93222 18.33155  1.000 28.39093 ? 242 LYS A CE  1 
ATOM   1727 N  NZ  . LYS A 1 242 ? 12.54664 -23.31347 19.50051  1.000 31.04350 ? 242 LYS A NZ  1 
ATOM   1728 N  N   . THR A 1 243 ? 16.46023 -28.51288 15.56648  1.000 16.76172 ? 243 THR A N   1 
ATOM   1729 C  CA  . THR A 1 243 ? 16.70023 -29.63996 14.67625  1.000 18.08952 ? 243 THR A CA  1 
ATOM   1730 C  C   . THR A 1 243 ? 18.18311 -29.69516 14.32856  1.000 17.28130 ? 243 THR A C   1 
ATOM   1731 O  O   . THR A 1 243 ? 18.97551 -28.85033 14.75475  1.000 18.35601 ? 243 THR A O   1 
ATOM   1732 C  CB  . THR A 1 243 ? 15.83905 -29.53135 13.41297  1.000 14.99940 ? 243 THR A CB  1 
ATOM   1733 O  OG1 . THR A 1 243 ? 15.97913 -30.72333 12.63031  1.000 18.98759 ? 243 THR A OG1 1 
ATOM   1734 C  CG2 . THR A 1 243 ? 16.26830 -28.33057 12.58208  1.000 15.08949 ? 243 THR A CG2 1 
ATOM   1735 N  N   . THR A 1 244 ? 18.55378 -30.70745 13.54558  1.000 20.16780 ? 244 THR A N   1 
ATOM   1736 C  CA  . THR A 1 244 ? 19.92586 -30.91613 13.10104  1.000 16.94067 ? 244 THR A CA  1 
ATOM   1737 C  C   . THR A 1 244 ? 19.95254 -30.98030 11.57756  1.000 14.63274 ? 244 THR A C   1 
ATOM   1738 O  O   . THR A 1 244 ? 18.91590 -30.91254 10.91299  1.000 17.86337 ? 244 THR A O   1 
ATOM   1739 C  CB  . THR A 1 244 ? 20.52578 -32.19117 13.71079  1.000 16.67436 ? 244 THR A CB  1 
ATOM   1740 O  OG1 . THR A 1 244 ? 19.85479 -33.34341 13.18291  1.000 15.82655 ? 244 THR A OG1 1 
ATOM   1741 C  CG2 . THR A 1 244 ? 20.37820 -32.17721 15.22716  1.000 20.37721 ? 244 THR A CG2 1 
ATOM   1742 N  N   . ALA A 1 245 ? 21.15786 -31.12672 11.02250  1.000 17.57824 ? 245 ALA A N   1 
ATOM   1743 C  CA  . ALA A 1 245 ? 21.31107 -31.14528 9.57000   1.000 19.30784 ? 245 ALA A CA  1 
ATOM   1744 C  C   . ALA A 1 245 ? 20.69198 -32.39353 8.95137   1.000 16.35415 ? 245 ALA A C   1 
ATOM   1745 O  O   . ALA A 1 245 ? 20.11380 -32.32909 7.85985   1.000 16.70400 ? 245 ALA A O   1 
ATOM   1746 C  CB  . ALA A 1 245 ? 22.79008 -31.04391 9.19935   1.000 15.15608 ? 245 ALA A CB  1 
ATOM   1747 N  N   . ALA A 1 246 ? 20.81148 -33.53895 9.62582   1.000 15.05016 ? 246 ALA A N   1 
ATOM   1748 C  CA  . ALA A 1 246 ? 20.27763 -34.78349 9.08698   1.000 17.15330 ? 246 ALA A CA  1 
ATOM   1749 C  C   . ALA A 1 246 ? 18.75303 -34.80736 9.07760   1.000 18.91421 ? 246 ALA A C   1 
ATOM   1750 O  O   . ALA A 1 246 ? 18.16102 -35.55226 8.28683   1.000 18.20987 ? 246 ALA A O   1 
ATOM   1751 C  CB  . ALA A 1 246 ? 20.81812 -35.97295 9.88376   1.000 20.17384 ? 246 ALA A CB  1 
ATOM   1752 N  N   . SER A 1 247 ? 18.10254 -33.99479 9.91645   1.000 14.87529 ? 247 SER A N   1 
ATOM   1753 C  CA  . SER A 1 247 ? 16.65321 -34.04688 10.06358  1.000 19.04104 ? 247 SER A CA  1 
ATOM   1754 C  C   . SER A 1 247 ? 15.97765 -32.68438 9.93775   1.000 18.37943 ? 247 SER A C   1 
ATOM   1755 O  O   . SER A 1 247 ? 14.80308 -32.55880 10.30405  1.000 15.63828 ? 247 SER A O   1 
ATOM   1756 C  CB  . SER A 1 247 ? 16.28213 -34.68149 11.41131  1.000 17.98594 ? 247 SER A CB  1 
ATOM   1757 O  OG  . SER A 1 247 ? 16.85772 -33.96673 12.49013  1.000 22.07865 ? 247 SER A OG  1 
ATOM   1758 N  N   . ALA A 1 248 ? 16.67462 -31.66542 9.42679   1.000 15.55353 ? 248 ALA A N   1 
ATOM   1759 C  CA  . ALA A 1 248 ? 16.06612 -30.34217 9.30943   1.000 13.93052 ? 248 ALA A CA  1 
ATOM   1760 C  C   . ALA A 1 248 ? 14.92451 -30.34095 8.30136   1.000 14.58303 ? 248 ALA A C   1 
ATOM   1761 O  O   . ALA A 1 248 ? 13.87297 -29.73796 8.54665   1.000 12.34294 ? 248 ALA A O   1 
ATOM   1762 C  CB  . ALA A 1 248 ? 17.12055 -29.30758 8.91619   1.000 19.18709 ? 248 ALA A CB  1 
ATOM   1763 N  N   . CYS A 1 249 ? 15.11667 -31.00879 7.16131   1.000 14.00585 ? 249 CYS A N   1 
ATOM   1764 C  CA  . CYS A 1 249 ? 14.08730 -31.03815 6.12730   1.000 11.43707 ? 249 CYS A CA  1 
ATOM   1765 C  C   . CYS A 1 249 ? 12.81917 -31.71688 6.62790   1.000 14.40655 ? 249 CYS A C   1 
ATOM   1766 O  O   . CYS A 1 249 ? 11.70594 -31.28005 6.31272   1.000 14.20051 ? 249 CYS A O   1 
ATOM   1767 C  CB  . CYS A 1 249 ? 14.62283 -31.75098 4.88611   1.000 13.75476 ? 249 CYS A CB  1 
ATOM   1768 S  SG  . CYS A 1 249 ? 13.56200 -31.66368 3.42688   1.000 10.62534 ? 249 CYS A SG  1 
ATOM   1769 N  N   . ARG A 1 250 ? 12.96647 -32.79074 7.40700   1.000 13.86796 ? 250 ARG A N   1 
ATOM   1770 C  CA  . ARG A 1 250 ? 11.79554 -33.46126 7.96234   1.000 15.57585 ? 250 ARG A CA  1 
ATOM   1771 C  C   . ARG A 1 250 ? 11.12040 -32.60212 9.02523   1.000 11.60892 ? 250 ARG A C   1 
ATOM   1772 O  O   . ARG A 1 250 ? 9.88701  -32.56014 9.10459   1.000 13.36247 ? 250 ARG A O   1 
ATOM   1773 C  CB  . ARG A 1 250 ? 12.19153 -34.82147 8.53724   1.000 14.78712 ? 250 ARG A CB  1 
ATOM   1774 N  N   . TYR A 1 251 ? 11.91074 -31.90894 9.84979   1.000 12.29178 ? 251 TYR A N   1 
ATOM   1775 C  CA  . TYR A 1 251 ? 11.33260 -31.01608 10.84997  1.000 14.70577 ? 251 TYR A CA  1 
ATOM   1776 C  C   . TYR A 1 251 ? 10.58224 -29.86541 10.19212  1.000 13.73824 ? 251 TYR A C   1 
ATOM   1777 O  O   . TYR A 1 251 ? 9.49628  -29.48351 10.64369  1.000 13.45363 ? 251 TYR A O   1 
ATOM   1778 C  CB  . TYR A 1 251 ? 12.42656 -30.47906 11.77482  1.000 17.11068 ? 251 TYR A CB  1 
ATOM   1779 C  CG  . TYR A 1 251 ? 11.91991 -29.53702 12.84919  1.000 13.35185 ? 251 TYR A CG  1 
ATOM   1780 C  CD1 . TYR A 1 251 ? 11.83924 -28.16729 12.62363  1.000 14.13335 ? 251 TYR A CD1 1 
ATOM   1781 C  CD2 . TYR A 1 251 ? 11.52623 -30.01853 14.09018  1.000 16.24906 ? 251 TYR A CD2 1 
ATOM   1782 C  CE1 . TYR A 1 251 ? 11.37500 -27.30641 13.60183  1.000 16.73157 ? 251 TYR A CE1 1 
ATOM   1783 C  CE2 . TYR A 1 251 ? 11.06251 -29.16511 15.07531  1.000 16.40723 ? 251 TYR A CE2 1 
ATOM   1784 C  CZ  . TYR A 1 251 ? 10.98933 -27.81054 14.82597  1.000 16.07668 ? 251 TYR A CZ  1 
ATOM   1785 O  OH  . TYR A 1 251 ? 10.52839 -26.95915 15.80407  1.000 15.98291 ? 251 TYR A OH  1 
ATOM   1786 N  N   . ILE A 1 252 ? 11.15389 -29.29307 9.13015   1.000 12.42787 ? 252 ILE A N   1 
ATOM   1787 C  CA  . ILE A 1 252 ? 10.50173 -28.19143 8.42723   1.000 11.21713 ? 252 ILE A CA  1 
ATOM   1788 C  C   . ILE A 1 252 ? 9.17994  -28.65170 7.82599   1.000 12.93248 ? 252 ILE A C   1 
ATOM   1789 O  O   . ILE A 1 252 ? 8.17482  -27.93097 7.87015   1.000 12.03864 ? 252 ILE A O   1 
ATOM   1790 C  CB  . ILE A 1 252 ? 11.44737 -27.61378 7.35679   1.000 11.89575 ? 252 ILE A CB  1 
ATOM   1791 C  CG1 . ILE A 1 252 ? 12.59843 -26.84986 8.01477   1.000 9.67725  ? 252 ILE A CG1 1 
ATOM   1792 C  CG2 . ILE A 1 252 ? 10.69411 -26.71069 6.39371   1.000 12.05260 ? 252 ILE A CG2 1 
ATOM   1793 C  CD1 . ILE A 1 252 ? 13.56851 -26.24430 7.02448   1.000 10.78785 ? 252 ILE A CD1 1 
ATOM   1794 N  N   . ALA A 1 253 ? 9.15472  -29.86414 7.26729   1.000 11.80430 ? 253 ALA A N   1 
ATOM   1795 C  CA  . ALA A 1 253 ? 7.91039  -30.39995 6.72591   1.000 13.27908 ? 253 ALA A CA  1 
ATOM   1796 C  C   . ALA A 1 253 ? 6.90218  -30.68448 7.83271   1.000 15.56047 ? 253 ALA A C   1 
ATOM   1797 O  O   . ALA A 1 253 ? 5.70013  -30.45260 7.65857   1.000 12.87359 ? 253 ALA A O   1 
ATOM   1798 C  CB  . ALA A 1 253 ? 8.19124  -31.66601 5.91652   1.000 11.39654 ? 253 ALA A CB  1 
ATOM   1799 N  N   . ASP A 1 254 ? 7.37187  -31.18247 8.97983   1.000 15.74464 ? 254 ASP A N   1 
ATOM   1800 C  CA  . ASP A 1 254 ? 6.45943  -31.52189 10.06689  1.000 14.65171 ? 254 ASP A CA  1 
ATOM   1801 C  C   . ASP A 1 254 ? 5.79708  -30.28707 10.66320  1.000 14.48272 ? 254 ASP A C   1 
ATOM   1802 O  O   . ASP A 1 254 ? 4.65544  -30.36434 11.13011  1.000 12.61223 ? 254 ASP A O   1 
ATOM   1803 C  CB  . ASP A 1 254 ? 7.20190  -32.29601 11.15678  1.000 14.29628 ? 254 ASP A CB  1 
ATOM   1804 C  CG  . ASP A 1 254 ? 7.45520  -33.74023 10.77739  1.000 18.79232 ? 254 ASP A CG  1 
ATOM   1805 O  OD1 . ASP A 1 254 ? 6.88279  -34.19939 9.76630   1.000 20.98613 ? 254 ASP A OD1 1 
ATOM   1806 O  OD2 . ASP A 1 254 ? 8.22496  -34.41672 11.48980  1.000 19.20021 ? 254 ASP A OD2 1 
ATOM   1807 N  N   . THR A 1 255 ? 6.48638  -29.14732 10.65812  1.000 9.91249  ? 255 THR A N   1 
ATOM   1808 C  CA  . THR A 1 255 ? 5.98917  -27.93067 11.28622  1.000 13.21999 ? 255 THR A CA  1 
ATOM   1809 C  C   . THR A 1 255 ? 5.49568  -26.90926 10.26807  1.000 16.07395 ? 255 THR A C   1 
ATOM   1810 O  O   . THR A 1 255 ? 5.36959  -25.72407 10.59365  1.000 13.34926 ? 255 THR A O   1 
ATOM   1811 C  CB  . THR A 1 255 ? 7.07580  -27.31481 12.16749  1.000 15.00257 ? 255 THR A CB  1 
ATOM   1812 O  OG1 . THR A 1 255 ? 8.23730  -27.03720 11.37401  1.000 13.01781 ? 255 THR A OG1 1 
ATOM   1813 C  CG2 . THR A 1 255 ? 7.45403  -28.27419 13.28554  1.000 12.76844 ? 255 THR A CG2 1 
ATOM   1814 N  N   . ALA A 1 256 ? 5.20231  -27.34380 9.04948   1.000 12.96067 ? 256 ALA A N   1 
ATOM   1815 C  CA  . ALA A 1 256 ? 4.81558  -26.43025 7.98847   1.000 13.75343 ? 256 ALA A CA  1 
ATOM   1816 C  C   . ALA A 1 256 ? 3.31349  -26.16851 8.00716   1.000 14.84096 ? 256 ALA A C   1 
ATOM   1817 O  O   . ALA A 1 256 ? 2.53071  -26.91294 8.60256   1.000 12.06290 ? 256 ALA A O   1 
ATOM   1818 C  CB  . ALA A 1 256 ? 5.23117  -26.98942 6.62648   1.000 11.41546 ? 256 ALA A CB  1 
ATOM   1819 N  N   . ASN A 1 257 ? 2.92223  -25.07952 7.34930   1.000 11.27889 ? 257 ASN A N   1 
ATOM   1820 C  CA  . ASN A 1 257 ? 1.51281  -24.81260 7.09504   1.000 18.43467 ? 257 ASN A CA  1 
ATOM   1821 C  C   . ASN A 1 257 ? 0.99864  -25.79757 6.05288   1.000 13.54284 ? 257 ASN A C   1 
ATOM   1822 O  O   . ASN A 1 257 ? 1.46231  -25.79763 4.90776   1.000 16.17675 ? 257 ASN A O   1 
ATOM   1823 C  CB  . ASN A 1 257 ? 1.32014  -23.37468 6.61977   1.000 17.88475 ? 257 ASN A CB  1 
ATOM   1824 C  CG  . ASN A 1 257 ? 1.42818  -22.36617 7.74801   1.000 18.80256 ? 257 ASN A CG  1 
ATOM   1825 O  OD1 . ASN A 1 257 ? 0.85589  -22.55514 8.82148   1.000 17.49029 ? 257 ASN A OD1 1 
ATOM   1826 N  ND2 . ASN A 1 257 ? 2.16107  -21.28449 7.50793   1.000 17.27416 ? 257 ASN A ND2 1 
ATOM   1827 N  N   . LYS A 1 258 ? 0.04892  -26.63988 6.44593   1.000 12.15876 ? 258 LYS A N   1 
ATOM   1828 C  CA  . LYS A 1 258 ? -0.43918 -27.71498 5.59375   1.000 15.39772 ? 258 LYS A CA  1 
ATOM   1829 C  C   . LYS A 1 258 ? -1.75954 -27.32840 4.94078   1.000 14.53433 ? 258 LYS A C   1 
ATOM   1830 O  O   . LYS A 1 258 ? -2.65150 -26.77877 5.59489   1.000 18.36679 ? 258 LYS A O   1 
ATOM   1831 C  CB  . LYS A 1 258 ? -0.61819 -29.00603 6.39509   1.000 17.08546 ? 258 LYS A CB  1 
ATOM   1832 N  N   . GLY A 1 259 ? -1.87844 -27.62595 3.64743   1.000 15.91166 ? 259 GLY A N   1 
ATOM   1833 C  CA  . GLY A 1 259 ? -3.13657 -27.43923 2.95521   1.000 15.34123 ? 259 GLY A CA  1 
ATOM   1834 C  C   . GLY A 1 259 ? -3.46364 -26.01512 2.58282   1.000 17.87890 ? 259 GLY A C   1 
ATOM   1835 O  O   . GLY A 1 259 ? -4.60904 -25.72792 2.22645   1.000 20.18439 ? 259 GLY A O   1 
ATOM   1836 N  N   . ASP A 1 260 ? -2.48954 -25.11064 2.64981   1.000 14.63324 ? 260 ASP A N   1 
ATOM   1837 C  CA  . ASP A 1 260 ? -2.73423 -23.70785 2.34806   1.000 16.43140 ? 260 ASP A CA  1 
ATOM   1838 C  C   . ASP A 1 260 ? -2.60020 -23.37304 0.86931   1.000 14.20973 ? 260 ASP A C   1 
ATOM   1839 O  O   . ASP A 1 260 ? -3.18054 -22.37743 0.42177   1.000 15.86840 ? 260 ASP A O   1 
ATOM   1840 C  CB  . ASP A 1 260 ? -1.77728 -22.81901 3.15073   1.000 20.54808 ? 260 ASP A CB  1 
ATOM   1841 C  CG  . ASP A 1 260 ? -2.24201 -22.60015 4.57596   1.000 24.22763 ? 260 ASP A CG  1 
ATOM   1842 O  OD1 . ASP A 1 260 ? -3.27325 -23.18840 4.96468   1.000 25.26550 ? 260 ASP A OD1 1 
ATOM   1843 O  OD2 . ASP A 1 260 ? -1.57807 -21.83298 5.30574   1.000 22.69621 ? 260 ASP A OD2 1 
ATOM   1844 N  N   . LEU A 1 261 ? -1.86750 -24.17245 0.10295   1.000 14.26158 ? 261 LEU A N   1 
ATOM   1845 C  CA  . LEU A 1 261 ? -1.57028 -23.83800 -1.28102  1.000 15.55671 ? 261 LEU A CA  1 
ATOM   1846 C  C   . LEU A 1 261 ? -2.65749 -24.34793 -2.22252  1.000 16.86728 ? 261 LEU A C   1 
ATOM   1847 O  O   . LEU A 1 261 ? -3.39313 -25.29040 -1.91835  1.000 18.43883 ? 261 LEU A O   1 
ATOM   1848 C  CB  . LEU A 1 261 ? -0.21190 -24.40867 -1.68899  1.000 14.05132 ? 261 LEU A CB  1 
ATOM   1849 C  CG  . LEU A 1 261 ? 0.99131  -23.83276 -0.93956  1.000 14.47633 ? 261 LEU A CG  1 
ATOM   1850 C  CD1 . LEU A 1 261 ? 2.26979  -24.54720 -1.34364  1.000 13.19304 ? 261 LEU A CD1 1 
ATOM   1851 C  CD2 . LEU A 1 261 ? 1.10916  -22.33563 -1.18360  1.000 14.48456 ? 261 LEU A CD2 1 
ATOM   1852 N  N   . SER A 1 262 ? -2.75003 -23.70007 -3.38087  1.000 20.71791 ? 262 SER A N   1 
ATOM   1853 C  CA  . SER A 1 262 ? -3.70089 -24.06465 -4.41649  1.000 17.93947 ? 262 SER A CA  1 
ATOM   1854 C  C   . SER A 1 262 ? -2.95580 -24.42884 -5.69382  1.000 19.89063 ? 262 SER A C   1 
ATOM   1855 O  O   . SER A 1 262 ? -1.78488 -24.08235 -5.87772  1.000 16.91182 ? 262 SER A O   1 
ATOM   1856 C  CB  . SER A 1 262 ? -4.69645 -22.92714 -4.69001  1.000 20.55120 ? 262 SER A CB  1 
ATOM   1857 O  OG  . SER A 1 262 ? -4.04122 -21.76862 -5.17410  1.000 25.18480 ? 262 SER A OG  1 
ATOM   1858 N  N   . ASN A 1 263 ? -3.66055 -25.13980 -6.57577  1.000 17.28087 ? 263 ASN A N   1 
ATOM   1859 C  CA  . ASN A 1 263 ? -3.10511 -25.63635 -7.83528  1.000 21.05048 ? 263 ASN A CA  1 
ATOM   1860 C  C   . ASN A 1 263 ? -1.93860 -26.59083 -7.59376  1.000 18.82006 ? 263 ASN A C   1 
ATOM   1861 O  O   . ASN A 1 263 ? -0.97518 -26.62604 -8.36376  1.000 20.22991 ? 263 ASN A O   1 
ATOM   1862 C  CB  . ASN A 1 263 ? -2.68575 -24.48634 -8.75759  1.000 18.23211 ? 263 ASN A CB  1 
ATOM   1863 C  CG  . ASN A 1 263 ? -2.55795 -24.91945 -10.20504 1.000 27.66415 ? 263 ASN A CG  1 
ATOM   1864 O  OD1 . ASN A 1 263 ? -2.87388 -26.05727 -10.55177 1.000 30.33533 ? 263 ASN A OD1 1 
ATOM   1865 N  ND2 . ASN A 1 263 ? -2.09723 -24.01283 -11.05870 1.000 29.06544 ? 263 ASN A ND2 1 
ATOM   1866 N  N   . ILE A 1 264 ? -2.01778 -27.36825 -6.51930  1.000 17.26970 ? 264 ILE A N   1 
ATOM   1867 C  CA  . ILE A 1 264 ? -1.03694 -28.40530 -6.22406  1.000 15.48015 ? 264 ILE A CA  1 
ATOM   1868 C  C   . ILE A 1 264 ? -1.53876 -29.70962 -6.83772  1.000 19.99602 ? 264 ILE A C   1 
ATOM   1869 O  O   . ILE A 1 264 ? -2.64732 -30.15032 -6.49440  1.000 18.72696 ? 264 ILE A O   1 
ATOM   1870 C  CB  . ILE A 1 264 ? -0.81776 -28.56264 -4.71540  1.000 19.70155 ? 264 ILE A CB  1 
ATOM   1871 C  CG1 . ILE A 1 264 ? -0.30801 -27.25449 -4.10986  1.000 16.18785 ? 264 ILE A CG1 1 
ATOM   1872 C  CG2 . ILE A 1 264 ? 0.15284  -29.70085 -4.43546  1.000 17.85410 ? 264 ILE A CG2 1 
ATOM   1873 C  CD1 . ILE A 1 264 ? 1.02897  -26.81131 -4.65611  1.000 15.40043 ? 264 ILE A CD1 1 
ATOM   1874 N  N   . PRO A 1 265 ? -0.78359 -30.34113 -7.73134  1.000 21.90966 ? 265 PRO A N   1 
ATOM   1875 C  CA  . PRO A 1 265 ? -1.24691 -31.59660 -8.33044  1.000 18.06293 ? 265 PRO A CA  1 
ATOM   1876 C  C   . PRO A 1 265 ? -1.31997 -32.71241 -7.30048  1.000 21.11565 ? 265 PRO A C   1 
ATOM   1877 O  O   . PRO A 1 265 ? -0.62934 -32.69523 -6.27835  1.000 23.30628 ? 265 PRO A O   1 
ATOM   1878 C  CB  . PRO A 1 265 ? -0.18649 -31.89576 -9.39854  1.000 20.26414 ? 265 PRO A CB  1 
ATOM   1879 C  CG  . PRO A 1 265 ? 0.52631  -30.58727 -9.62258  1.000 21.27201 ? 265 PRO A CG  1 
ATOM   1880 C  CD  . PRO A 1 265 ? 0.49952  -29.89683 -8.29788  1.000 18.02648 ? 265 PRO A CD  1 
ATOM   1881 N  N   . PHE A 1 266 ? -2.17679 -33.69226 -7.58223  1.000 23.82743 ? 266 PHE A N   1 
ATOM   1882 C  CA  . PHE A 1 266 ? -2.31738 -34.83336 -6.68831  1.000 20.63945 ? 266 PHE A CA  1 
ATOM   1883 C  C   . PHE A 1 266 ? -1.02342 -35.63596 -6.66060  1.000 18.55229 ? 266 PHE A C   1 
ATOM   1884 O  O   . PHE A 1 266 ? -0.43979 -35.93607 -7.70611  1.000 23.50585 ? 266 PHE A O   1 
ATOM   1885 C  CB  . PHE A 1 266 ? -3.48383 -35.71729 -7.12873  1.000 21.37116 ? 266 PHE A CB  1 
ATOM   1886 C  CG  . PHE A 1 266 ? -3.99156 -36.62855 -6.04744  1.000 20.24747 ? 266 PHE A CG  1 
ATOM   1887 C  CD1 . PHE A 1 266 ? -5.07582 -36.26018 -5.26724  1.000 21.11525 ? 266 PHE A CD1 1 
ATOM   1888 C  CD2 . PHE A 1 266 ? -3.38020 -37.84773 -5.80366  1.000 22.01482 ? 266 PHE A CD2 1 
ATOM   1889 C  CE1 . PHE A 1 266 ? -5.54314 -37.09090 -4.26660  1.000 23.15287 ? 266 PHE A CE1 1 
ATOM   1890 C  CE2 . PHE A 1 266 ? -3.84366 -38.68469 -4.80563  1.000 20.47894 ? 266 PHE A CE2 1 
ATOM   1891 C  CZ  . PHE A 1 266 ? -4.92794 -38.30656 -4.03729  1.000 23.41542 ? 266 PHE A CZ  1 
ATOM   1892 N  N   . GLY A 1 267 ? -0.57680 -35.98382 -5.45667  1.000 19.43394 ? 267 GLY A N   1 
ATOM   1893 C  CA  . GLY A 1 267 ? 0.70253  -36.62778 -5.26124  1.000 19.68873 ? 267 GLY A CA  1 
ATOM   1894 C  C   . GLY A 1 267 ? 1.81335  -35.69155 -4.83928  1.000 15.35218 ? 267 GLY A C   1 
ATOM   1895 O  O   . GLY A 1 267 ? 2.88419  -36.16620 -4.43956  1.000 14.16646 ? 267 GLY A O   1 
ATOM   1896 N  N   . THR A 1 268 ? 1.59228  -34.38358 -4.92079  1.000 11.42568 ? 268 THR A N   1 
ATOM   1897 C  CA  . THR A 1 268 ? 2.55190  -33.38854 -4.46798  1.000 15.56843 ? 268 THR A CA  1 
ATOM   1898 C  C   . THR A 1 268 ? 2.12773  -32.86499 -3.10257  1.000 15.70740 ? 268 THR A C   1 
ATOM   1899 O  O   . THR A 1 268 ? 0.94342  -32.60718 -2.86597  1.000 13.07594 ? 268 THR A O   1 
ATOM   1900 C  CB  . THR A 1 268 ? 2.65557  -32.23331 -5.46779  1.000 15.67362 ? 268 THR A CB  1 
ATOM   1901 O  OG1 . THR A 1 268 ? 3.05293  -32.74220 -6.74764  1.000 14.32063 ? 268 THR A OG1 1 
ATOM   1902 C  CG2 . THR A 1 268 ? 3.67500  -31.20287 -5.00142  1.000 12.58032 ? 268 THR A CG2 1 
ATOM   1903 N  N   . VAL A 1 269 ? 3.10061  -32.72442 -2.19945  1.000 15.36601 ? 269 VAL A N   1 
ATOM   1904 C  CA  . VAL A 1 269 ? 2.79134  -32.25828 -0.85689  1.000 13.03662 ? 269 VAL A CA  1 
ATOM   1905 C  C   . VAL A 1 269 ? 2.26509  -30.82618 -0.91090  1.000 13.34521 ? 269 VAL A C   1 
ATOM   1906 O  O   . VAL A 1 269 ? 2.64388  -30.02616 -1.77659  1.000 14.17826 ? 269 VAL A O   1 
ATOM   1907 C  CB  . VAL A 1 269 ? 4.02433  -32.35901 0.05784   1.000 16.51161 ? 269 VAL A CB  1 
ATOM   1908 C  CG1 . VAL A 1 269 ? 4.47274  -33.80733 0.18281   1.000 15.04419 ? 269 VAL A CG1 1 
ATOM   1909 C  CG2 . VAL A 1 269 ? 5.15716  -31.48809 -0.47026  1.000 15.29877 ? 269 VAL A CG2 1 
ATOM   1910 N  N   . ASN A 1 270 ? 1.36371  -30.50952 0.01412   1.000 12.64368 ? 270 ASN A N   1 
ATOM   1911 C  CA  . ASN A 1 270 ? 0.83017  -29.16112 0.18235   1.000 15.77076 ? 270 ASN A CA  1 
ATOM   1912 C  C   . ASN A 1 270 ? 1.38350  -28.63073 1.50170   1.000 13.16983 ? 270 ASN A C   1 
ATOM   1913 O  O   . ASN A 1 270 ? 0.68207  -28.55234 2.51077   1.000 15.35937 ? 270 ASN A O   1 
ATOM   1914 C  CB  . ASN A 1 270 ? -0.70919 -29.16381 0.15809   1.000 12.09032 ? 270 ASN A CB  1 
ATOM   1915 C  CG  . ASN A 1 270 ? -1.29681 -27.76814 0.03754   1.000 15.14099 ? 270 ASN A CG  1 
ATOM   1916 O  OD1 . ASN A 1 270 ? -0.72915 -26.79460 0.53261   1.000 17.24361 ? 270 ASN A OD1 1 
ATOM   1917 N  ND2 . ASN A 1 270 ? -2.44336 -27.66646 -0.62438  1.000 17.14657 ? 270 ASN A ND2 1 
ATOM   1918 N  N   . LEU A 1 271 ? 2.66567  -28.27193 1.48678   1.000 14.28819 ? 271 LEU A N   1 
ATOM   1919 C  CA  . LEU A 1 271 ? 3.37730  -27.83770 2.68099   1.000 12.28752 ? 271 LEU A CA  1 
ATOM   1920 C  C   . LEU A 1 271 ? 4.12878  -26.55074 2.37855   1.000 13.52748 ? 271 LEU A C   1 
ATOM   1921 O  O   . LEU A 1 271 ? 4.83706  -26.46416 1.37039   1.000 10.87233 ? 271 LEU A O   1 
ATOM   1922 C  CB  . LEU A 1 271 ? 4.34641  -28.92160 3.16462   1.000 12.38039 ? 271 LEU A CB  1 
ATOM   1923 C  CG  . LEU A 1 271 ? 3.71675  -30.26543 3.53651   1.000 16.18978 ? 271 LEU A CG  1 
ATOM   1924 C  CD1 . LEU A 1 271 ? 4.78689  -31.32603 3.73551   1.000 13.92650 ? 271 LEU A CD1 1 
ATOM   1925 C  CD2 . LEU A 1 271 ? 2.85773  -30.12605 4.78384   1.000 13.31278 ? 271 LEU A CD2 1 
ATOM   1926 N  N   . LEU A 1 272 ? 3.97691  -25.55899 3.25271   1.000 11.99510 ? 272 LEU A N   1 
ATOM   1927 C  CA  . LEU A 1 272 ? 4.59734  -24.25111 3.08849   1.000 13.97109 ? 272 LEU A CA  1 
ATOM   1928 C  C   . LEU A 1 272 ? 5.48104  -23.96080 4.29299   1.000 11.94237 ? 272 LEU A C   1 
ATOM   1929 O  O   . LEU A 1 272 ? 5.03782  -24.09899 5.43766   1.000 10.08045 ? 272 LEU A O   1 
ATOM   1930 C  CB  . LEU A 1 272 ? 3.53531  -23.15972 2.92710   1.000 14.90887 ? 272 LEU A CB  1 
ATOM   1931 C  CG  . LEU A 1 272 ? 4.02405  -21.74425 2.61725   1.000 12.78197 ? 272 LEU A CG  1 
ATOM   1932 C  CD1 . LEU A 1 272 ? 4.79649  -21.71535 1.30799   1.000 12.76235 ? 272 LEU A CD1 1 
ATOM   1933 C  CD2 . LEU A 1 272 ? 2.85001  -20.78333 2.56888   1.000 12.27362 ? 272 LEU A CD2 1 
ATOM   1934 N  N   . ALA A 1 273 ? 6.72251  -23.55264 4.02980   1.000 11.94747 ? 273 ALA A N   1 
ATOM   1935 C  CA  . ALA A 1 273 ? 7.69099  -23.32775 5.09669   1.000 13.78449 ? 273 ALA A CA  1 
ATOM   1936 C  C   . ALA A 1 273 ? 7.17792  -22.29715 6.09646   1.000 13.16535 ? 273 ALA A C   1 
ATOM   1937 O  O   . ALA A 1 273 ? 6.52903  -21.31486 5.72646   1.000 11.38824 ? 273 ALA A O   1 
ATOM   1938 C  CB  . ALA A 1 273 ? 9.02680  -22.87221 4.50838   1.000 14.25269 ? 273 ALA A CB  1 
ATOM   1939 N  N   . TYR A 1 274 ? 7.48581  -22.52428 7.37334   1.000 13.91010 ? 274 TYR A N   1 
ATOM   1940 C  CA  . TYR A 1 274 ? 6.91039  -21.73944 8.45916   1.000 14.50909 ? 274 TYR A CA  1 
ATOM   1941 C  C   . TYR A 1 274 ? 7.78403  -21.90635 9.69458   1.000 15.78895 ? 274 TYR A C   1 
ATOM   1942 O  O   . TYR A 1 274 ? 8.16671  -23.03093 10.03131  1.000 16.41690 ? 274 TYR A O   1 
ATOM   1943 C  CB  . TYR A 1 274 ? 5.46759  -22.19054 8.72560   1.000 13.78233 ? 274 TYR A CB  1 
ATOM   1944 C  CG  . TYR A 1 274 ? 4.79896  -21.55868 9.92336   1.000 17.76476 ? 274 TYR A CG  1 
ATOM   1945 C  CD1 . TYR A 1 274 ? 4.73029  -20.17963 10.06156  1.000 14.76799 ? 274 TYR A CD1 1 
ATOM   1946 C  CD2 . TYR A 1 274 ? 4.20652  -22.34626 10.90198  1.000 18.39361 ? 274 TYR A CD2 1 
ATOM   1947 C  CE1 . TYR A 1 274 ? 4.10989  -19.60276 11.15280  1.000 16.70582 ? 274 TYR A CE1 1 
ATOM   1948 C  CE2 . TYR A 1 274 ? 3.58220  -21.77935 11.99442  1.000 20.25414 ? 274 TYR A CE2 1 
ATOM   1949 C  CZ  . TYR A 1 274 ? 3.53746  -20.40808 12.11605  1.000 21.23900 ? 274 TYR A CZ  1 
ATOM   1950 O  OH  . TYR A 1 274 ? 2.91656  -19.84130 13.20469  1.000 21.19509 ? 274 TYR A OH  1 
ATOM   1951 N  N   . ASN A 1 275 ? 8.10246  -20.79284 10.36162  1.000 15.87402 ? 275 ASN A N   1 
ATOM   1952 C  CA  . ASN A 1 275 ? 9.06756  -20.80770 11.45595  1.000 14.38684 ? 275 ASN A CA  1 
ATOM   1953 C  C   . ASN A 1 275 ? 8.43370  -20.99913 12.82953  1.000 14.98987 ? 275 ASN A C   1 
ATOM   1954 O  O   . ASN A 1 275 ? 9.16661  -21.20569 13.80262  1.000 15.49178 ? 275 ASN A O   1 
ATOM   1955 C  CB  . ASN A 1 275 ? 9.90783  -19.51808 11.44975  1.000 11.60613 ? 275 ASN A CB  1 
ATOM   1956 C  CG  . ASN A 1 275 ? 9.07942  -18.26222 11.68050  1.000 14.68567 ? 275 ASN A CG  1 
ATOM   1957 O  OD1 . ASN A 1 275 ? 7.86733  -18.32215 11.88272  1.000 19.48957 ? 275 ASN A OD1 1 
ATOM   1958 N  ND2 . ASN A 1 275 ? 9.74373  -17.11180 11.66041  1.000 15.40987 ? 275 ASN A ND2 1 
ATOM   1959 N  N   . ASN A 1 276 ? 7.10477  -20.92763 12.93146  1.000 18.91357 ? 276 ASN A N   1 
ATOM   1960 C  CA  . ASN A 1 276 ? 6.38599  -21.19716 14.17849  1.000 19.00197 ? 276 ASN A CA  1 
ATOM   1961 C  C   . ASN A 1 276 ? 6.82452  -20.25560 15.29919  1.000 16.67602 ? 276 ASN A C   1 
ATOM   1962 O  O   . ASN A 1 276 ? 6.87885  -20.63946 16.46954  1.000 19.03516 ? 276 ASN A O   1 
ATOM   1963 C  CB  . ASN A 1 276 ? 6.54896  -22.65989 14.60246  1.000 20.98870 ? 276 ASN A CB  1 
ATOM   1964 C  CG  . ASN A 1 276 ? 5.85466  -23.62182 13.65914  1.000 22.56964 ? 276 ASN A CG  1 
ATOM   1965 O  OD1 . ASN A 1 276 ? 6.38105  -23.95878 12.59933  1.000 22.16983 ? 276 ASN A OD1 1 
ATOM   1966 N  ND2 . ASN A 1 276 ? 4.66851  -24.07841 14.04695  1.000 21.68320 ? 276 ASN A ND2 1 
ATOM   1967 N  N   . TYR A 1 277 ? 7.13547  -19.01079 14.94422  1.000 15.62879 ? 277 TYR A N   1 
ATOM   1968 C  CA  . TYR A 1 277 ? 7.59319  -18.05301 15.94084  1.000 20.42104 ? 277 TYR A CA  1 
ATOM   1969 C  C   . TYR A 1 277 ? 6.43924  -17.60246 16.82726  1.000 19.96678 ? 277 TYR A C   1 
ATOM   1970 O  O   . TYR A 1 277 ? 5.32725  -17.35149 16.35342  1.000 18.83172 ? 277 TYR A O   1 
ATOM   1971 C  CB  . TYR A 1 277 ? 8.23955  -16.84028 15.27053  1.000 21.37675 ? 277 TYR A CB  1 
ATOM   1972 C  CG  . TYR A 1 277 ? 8.70441  -15.78806 16.25809  1.000 20.80753 ? 277 TYR A CG  1 
ATOM   1973 C  CD1 . TYR A 1 277 ? 9.89733  -15.93894 16.95415  1.000 24.83416 ? 277 TYR A CD1 1 
ATOM   1974 C  CD2 . TYR A 1 277 ? 7.94711  -14.64884 16.49912  1.000 22.20153 ? 277 TYR A CD2 1 
ATOM   1975 C  CE1 . TYR A 1 277 ? 10.32280 -14.98368 17.86003  1.000 25.04843 ? 277 TYR A CE1 1 
ATOM   1976 C  CE2 . TYR A 1 277 ? 8.36585  -13.68775 17.40161  1.000 24.39298 ? 277 TYR A CE2 1 
ATOM   1977 C  CZ  . TYR A 1 277 ? 9.55355  -13.85951 18.07908  1.000 25.42359 ? 277 TYR A CZ  1 
ATOM   1978 O  OH  . TYR A 1 277 ? 9.97046  -12.90263 18.97836  1.000 24.93308 ? 277 TYR A OH  1 
ATOM   1979 N  N   . GLN A 1 278 ? 6.71513  -17.50317 18.12576  1.000 19.47423 ? 278 GLN A N   1 
ATOM   1980 C  CA  . GLN A 1 278 ? 5.74308  -17.03344 19.10557  1.000 28.49137 ? 278 GLN A CA  1 
ATOM   1981 C  C   . GLN A 1 278 ? 6.45821  -16.09726 20.06493  1.000 28.69663 ? 278 GLN A C   1 
ATOM   1982 O  O   . GLN A 1 278 ? 7.45560  -16.48469 20.68068  1.000 29.11864 ? 278 GLN A O   1 
ATOM   1983 C  CB  . GLN A 1 278 ? 5.10257  -18.20107 19.86357  1.000 33.20045 ? 278 GLN A CB  1 
ATOM   1984 N  N   . ALA A 1 279 ? 5.95870  -14.87117 20.18188  1.000 31.30854 ? 279 ALA A N   1 
ATOM   1985 C  CA  . ALA A 1 279 ? 6.57172  -13.86996 21.04826  1.000 28.12085 ? 279 ALA A CA  1 
ATOM   1986 C  C   . ALA A 1 279 ? 6.46222  -14.26619 22.51787  1.000 32.59392 ? 279 ALA A C   1 
ATOM   1987 O  O   . ALA A 1 279 ? 7.29599  -13.88532 23.33895  1.000 39.71976 ? 279 ALA A O   1 
ATOM   1988 C  CB  . ALA A 1 279 ? 5.93202  -12.51099 20.81751  1.000 31.70905 ? 279 ALA A CB  1 
ATOM   1989 O  OXT . ALA A 1 279 ? 5.54074  -14.97713 22.91877  1.000 30.43853 ? 279 ALA A OXT 1 
HETATM 1990 CA CA  . CA  B 2 .   ? 13.79571 -35.27827 0.01312   1.000 11.99057 ? 501 CA  A CA  1 
HETATM 1991 CA CA  . CA  C 2 .   ? -3.29491 -21.22465 6.74159   1.000 23.04285 ? 502 CA  A CA  1 
HETATM 1992 N  N   . NO3 D 3 .   ? 33.05523 -16.36954 -15.81616 1.000 32.04864 ? 503 NO3 A N   1 
HETATM 1993 O  O1  . NO3 D 3 .   ? 34.23456 -16.52299 -16.15727 1.000 29.31614 ? 503 NO3 A O1  1 
HETATM 1994 O  O2  . NO3 D 3 .   ? 32.75199 -16.37715 -14.61733 1.000 25.85949 ? 503 NO3 A O2  1 
HETATM 1995 O  O3  . NO3 D 3 .   ? 32.17851 -16.20844 -16.67354 1.000 27.97226 ? 503 NO3 A O3  1 
HETATM 1996 O  O   . HOH E 4 .   ? 8.92406  -36.33847 -8.86125  1.000 20.73571 ? 601 HOH A O   1 
HETATM 1997 O  O   . HOH E 4 .   ? 8.38018  -37.99091 -7.51521  1.000 25.57057 ? 602 HOH A O   1 
HETATM 1998 O  O   . HOH E 4 .   ? -4.51827 -8.06343  -4.51634  1.000 41.33372 ? 603 HOH A O   1 
HETATM 1999 O  O   . HOH E 4 .   ? 9.52747  -15.89229 21.42386  1.000 31.98955 ? 604 HOH A O   1 
HETATM 2000 O  O   . HOH E 4 .   ? 30.06140 -14.72800 10.74333  1.000 26.14702 ? 605 HOH A O   1 
HETATM 2001 O  O   . HOH E 4 .   ? 34.62575 -35.32099 -6.66542  1.000 24.88577 ? 606 HOH A O   1 
HETATM 2002 O  O   . HOH E 4 .   ? 14.98999 -20.68554 -10.91864 1.000 21.86169 ? 607 HOH A O   1 
HETATM 2003 O  O   . HOH E 4 .   ? 29.61281 -34.26488 -3.43206  1.000 20.49010 ? 608 HOH A O   1 
HETATM 2004 O  O   . HOH E 4 .   ? 0.41824  -23.75465 10.82989  1.000 22.43742 ? 609 HOH A O   1 
HETATM 2005 O  O   . HOH E 4 .   ? 13.53378 -23.77393 21.61821  1.000 28.93851 ? 610 HOH A O   1 
HETATM 2006 O  O   . HOH E 4 .   ? 4.44207  -20.15983 5.88755   1.000 12.55668 ? 611 HOH A O   1 
HETATM 2007 O  O   . HOH E 4 .   ? 18.23820 -18.02350 14.82271  1.000 17.12701 ? 612 HOH A O   1 
HETATM 2008 O  O   . HOH E 4 .   ? 10.43765 -34.49044 3.03116   1.000 19.61579 ? 613 HOH A O   1 
HETATM 2009 O  O   . HOH E 4 .   ? 15.68993 -24.90313 21.58875  1.000 27.42768 ? 614 HOH A O   1 
HETATM 2010 O  O   . HOH E 4 .   ? 20.21905 -41.33488 -2.15580  1.000 21.84474 ? 615 HOH A O   1 
HETATM 2011 O  O   . HOH E 4 .   ? -3.82336 -19.94618 2.13646   1.000 10.30580 ? 616 HOH A O   1 
HETATM 2012 O  O   . HOH E 4 .   ? 33.04518 -35.65671 -1.41329  1.000 24.41246 ? 617 HOH A O   1 
HETATM 2013 O  O   . HOH E 4 .   ? 14.61868 -34.74156 -2.38590  1.000 13.30887 ? 618 HOH A O   1 
HETATM 2014 O  O   . HOH E 4 .   ? 19.02664 -37.27439 6.71671   1.000 28.02056 ? 619 HOH A O   1 
HETATM 2015 O  O   . HOH E 4 .   ? 2.858    -13.718   11.691    1.000 30.09063 ? 620 HOH A O   1 
HETATM 2016 O  O   . HOH E 4 .   ? 8.71751  -33.59522 13.80175  1.000 31.69175 ? 621 HOH A O   1 
HETATM 2017 O  O   . HOH E 4 .   ? -4.44703 -19.76992 -3.72126  1.000 28.29945 ? 622 HOH A O   1 
HETATM 2018 O  O   . HOH E 4 .   ? 0.50226  -25.32092 2.64129   1.000 14.63939 ? 623 HOH A O   1 
HETATM 2019 O  O   . HOH E 4 .   ? 20.88766 -20.87640 -3.32958  1.000 15.38217 ? 624 HOH A O   1 
HETATM 2020 O  O   . HOH E 4 .   ? 16.75300 -15.10370 -4.10514  1.000 10.50339 ? 625 HOH A O   1 
HETATM 2021 O  O   . HOH E 4 .   ? 31.96890 -25.12492 -15.30551 1.000 24.64578 ? 626 HOH A O   1 
HETATM 2022 O  O   . HOH E 4 .   ? 2.07269  -13.29543 5.09544   1.000 14.95117 ? 627 HOH A O   1 
HETATM 2023 O  O   . HOH E 4 .   ? 30.14879 -7.81704  -8.09398  1.000 19.39549 ? 628 HOH A O   1 
HETATM 2024 O  O   . HOH E 4 .   ? 3.83702  -12.37127 9.05950   1.000 19.60369 ? 629 HOH A O   1 
HETATM 2025 O  O   . HOH E 4 .   ? 17.35873 -9.46838  -14.06420 1.000 19.27995 ? 630 HOH A O   1 
HETATM 2026 O  O   . HOH E 4 .   ? 17.71577 -29.23928 -8.83234  1.000 17.92528 ? 631 HOH A O   1 
HETATM 2027 O  O   . HOH E 4 .   ? 33.20182 -13.34879 -12.77256 1.000 20.55901 ? 632 HOH A O   1 
HETATM 2028 O  O   . HOH E 4 .   ? 6.49998  -33.87477 -15.98314 1.000 28.04526 ? 633 HOH A O   1 
HETATM 2029 O  O   . HOH E 4 .   ? 5.82812  -33.92791 -2.87716  1.000 12.95128 ? 634 HOH A O   1 
HETATM 2030 O  O   . HOH E 4 .   ? 34.64519 -34.07481 0.00000   0.50  13.78424 ? 635 HOH A O   1 
HETATM 2031 O  O   . HOH E 4 .   ? 0.65250  -18.36563 -9.63718  1.000 23.60386 ? 636 HOH A O   1 
HETATM 2032 O  O   . HOH E 4 .   ? 6.87690  -38.49516 -13.05182 1.000 30.48241 ? 637 HOH A O   1 
HETATM 2033 O  O   . HOH E 4 .   ? 37.85406 -32.41230 5.11198   1.000 13.06697 ? 638 HOH A O   1 
HETATM 2034 O  O   . HOH E 4 .   ? 16.23938 -23.08009 -10.44491 1.000 18.69241 ? 639 HOH A O   1 
HETATM 2035 O  O   . HOH E 4 .   ? 10.14345 -31.27237 -19.21365 1.000 28.60402 ? 640 HOH A O   1 
HETATM 2036 O  O   . HOH E 4 .   ? 21.77862 -8.34400  10.32374  1.000 20.53037 ? 641 HOH A O   1 
HETATM 2037 O  O   . HOH E 4 .   ? 9.60021  -11.60246 -0.64772  1.000 12.84343 ? 642 HOH A O   1 
HETATM 2038 O  O   . HOH E 4 .   ? 33.98152 -33.48318 -10.97081 1.000 20.46422 ? 643 HOH A O   1 
HETATM 2039 O  O   . HOH E 4 .   ? 40.75620 -18.75980 -10.30416 1.000 25.05358 ? 644 HOH A O   1 
HETATM 2040 O  O   . HOH E 4 .   ? 16.87686 -13.34574 11.12996  1.000 17.85046 ? 645 HOH A O   1 
HETATM 2041 O  O   . HOH E 4 .   ? 11.86701 -36.28877 -1.62418  1.000 15.58057 ? 646 HOH A O   1 
HETATM 2042 O  O   . HOH E 4 .   ? -3.50287 -12.48779 7.25963   1.000 22.65646 ? 647 HOH A O   1 
HETATM 2043 O  O   . HOH E 4 .   ? 35.70561 -15.16143 -13.79348 1.000 25.60495 ? 648 HOH A O   1 
HETATM 2044 O  O   . HOH E 4 .   ? 8.14423  -25.11746 8.31627   1.000 13.82819 ? 649 HOH A O   1 
HETATM 2045 O  O   . HOH E 4 .   ? 9.28028  -24.63658 12.05214  1.000 17.03029 ? 650 HOH A O   1 
HETATM 2046 O  O   . HOH E 4 .   ? 22.60862 -41.26023 -8.05331  1.000 19.64992 ? 651 HOH A O   1 
HETATM 2047 O  O   . HOH E 4 .   ? 5.52732  -37.72741 -9.03883  1.000 22.53359 ? 652 HOH A O   1 
HETATM 2048 O  O   . HOH E 4 .   ? 17.40851 -33.69072 15.13768  1.000 29.55502 ? 653 HOH A O   1 
HETATM 2049 O  O   . HOH E 4 .   ? 9.15732  -9.54866  -2.55540  1.000 16.11067 ? 654 HOH A O   1 
HETATM 2050 O  O   . HOH E 4 .   ? 20.80613 -21.49712 -11.63331 1.000 16.53781 ? 655 HOH A O   1 
HETATM 2051 O  O   . HOH E 4 .   ? 9.99492  -22.43412 16.09322  1.000 27.34418 ? 656 HOH A O   1 
HETATM 2052 O  O   . HOH E 4 .   ? -1.77950 -22.31219 8.15196   1.000 22.93929 ? 657 HOH A O   1 
HETATM 2053 O  O   . HOH E 4 .   ? 12.73304 -17.34096 10.80334  1.000 10.77477 ? 658 HOH A O   1 
HETATM 2054 O  O   . HOH E 4 .   ? 25.89552 -29.32835 10.18118  1.000 11.26417 ? 659 HOH A O   1 
HETATM 2055 O  O   . HOH E 4 .   ? 14.36131 -11.78839 -0.07452  1.000 9.71640  ? 660 HOH A O   1 
HETATM 2056 O  O   . HOH E 4 .   ? 27.81344 -18.39862 -5.02453  1.000 13.62426 ? 661 HOH A O   1 
HETATM 2057 O  O   . HOH E 4 .   ? 13.49222 -39.44349 -7.19175  1.000 24.97882 ? 662 HOH A O   1 
HETATM 2058 O  O   . HOH E 4 .   ? 3.34759  -12.06982 2.62689   1.000 15.39410 ? 663 HOH A O   1 
HETATM 2059 O  O   . HOH E 4 .   ? -5.21778 -25.12359 5.16508   1.000 26.61271 ? 664 HOH A O   1 
HETATM 2060 O  O   . HOH E 4 .   ? -1.79885 -32.48503 -2.65785  1.000 21.26839 ? 665 HOH A O   1 
HETATM 2061 O  O   . HOH E 4 .   ? 12.42597 -18.27745 21.00014  1.000 32.45852 ? 666 HOH A O   1 
HETATM 2062 O  O   . HOH E 4 .   ? 1.97931  -34.78476 -8.44700  1.000 18.18203 ? 667 HOH A O   1 
HETATM 2063 O  O   . HOH E 4 .   ? 7.86042  -33.58397 2.80837   1.000 15.00104 ? 668 HOH A O   1 
HETATM 2064 O  O   . HOH E 4 .   ? 14.840   -6.977    19.453    1.000 26.45580 ? 669 HOH A O   1 
HETATM 2065 O  O   . HOH E 4 .   ? 28.68233 -18.37070 11.89885  1.000 22.10144 ? 670 HOH A O   1 
HETATM 2066 O  O   . HOH E 4 .   ? 12.12341 -13.72466 -12.88147 1.000 19.23471 ? 671 HOH A O   1 
HETATM 2067 O  O   . HOH E 4 .   ? 17.70671 -32.21165 6.39607   1.000 15.31743 ? 672 HOH A O   1 
HETATM 2068 O  O   . HOH E 4 .   ? 4.31471  -17.32128 -10.41546 1.000 14.27605 ? 673 HOH A O   1 
HETATM 2069 O  O   . HOH E 4 .   ? 31.18427 -9.69375  -7.18727  1.000 23.85793 ? 674 HOH A O   1 
HETATM 2070 O  O   . HOH E 4 .   ? 4.28562  -33.87268 10.83755  1.000 28.79841 ? 675 HOH A O   1 
HETATM 2071 O  O   . HOH E 4 .   ? 35.87806 -27.23862 12.05263  1.000 26.20452 ? 676 HOH A O   1 
HETATM 2072 O  O   . HOH E 4 .   ? 29.31023 -38.01670 -8.28843  1.000 15.99591 ? 677 HOH A O   1 
HETATM 2073 O  O   . HOH E 4 .   ? 9.08362  -34.22964 -15.95005 1.000 23.97458 ? 678 HOH A O   1 
HETATM 2074 O  O   . HOH E 4 .   ? 35.12858 -12.43523 -0.64581  1.000 21.95370 ? 679 HOH A O   1 
HETATM 2075 O  O   . HOH E 4 .   ? 10.83326 -19.50848 15.68236  1.000 19.87064 ? 680 HOH A O   1 
HETATM 2076 O  O   . HOH E 4 .   ? 1.08376  -13.18318 1.24632   1.000 18.47898 ? 681 HOH A O   1 
HETATM 2077 O  O   . HOH E 4 .   ? 16.89691 -33.97134 3.52235   1.000 15.94503 ? 682 HOH A O   1 
HETATM 2078 O  O   . HOH E 4 .   ? 22.71763 -21.41114 -5.20342  1.000 12.99594 ? 683 HOH A O   1 
HETATM 2079 O  O   . HOH E 4 .   ? 34.08833 -11.71157 -15.76459 1.000 26.50425 ? 684 HOH A O   1 
HETATM 2080 O  O   . HOH E 4 .   ? 4.30118  -13.33126 -5.50053  1.000 12.70914 ? 685 HOH A O   1 
HETATM 2081 O  O   . HOH E 4 .   ? 17.03210 -19.47301 -11.90847 1.000 31.55760 ? 686 HOH A O   1 
HETATM 2082 O  O   . HOH E 4 .   ? 22.43926 -38.66666 1.67720   1.000 10.04934 ? 687 HOH A O   1 
HETATM 2083 O  O   . HOH E 4 .   ? 18.34198 -31.66822 3.48995   1.000 13.98472 ? 688 HOH A O   1 
HETATM 2084 O  O   . HOH E 4 .   ? 9.45505  -0.74663  12.71493  1.000 25.84111 ? 689 HOH A O   1 
HETATM 2085 O  O   . HOH E 4 .   ? -5.17927 -29.08770 -7.47850  1.000 25.57075 ? 690 HOH A O   1 
HETATM 2086 O  O   . HOH E 4 .   ? 1.58636  -15.64305 -9.84662  1.000 32.08386 ? 691 HOH A O   1 
HETATM 2087 O  O   . HOH E 4 .   ? 9.84486  -24.32600 14.73929  1.000 20.41321 ? 692 HOH A O   1 
HETATM 2088 O  O   . HOH E 4 .   ? 40.14327 -29.77260 9.72912   1.000 23.88748 ? 693 HOH A O   1 
HETATM 2089 O  O   . HOH E 4 .   ? 22.81734 -40.55782 -15.24959 1.000 19.22937 ? 694 HOH A O   1 
HETATM 2090 O  O   . HOH E 4 .   ? 14.919   -33.823   -18.351   1.000 18.55584 ? 695 HOH A O   1 
HETATM 2091 O  O   . HOH E 4 .   ? 3.654    -14.461   18.411    1.000 27.13432 ? 696 HOH A O   1 
HETATM 2092 O  O   . HOH E 4 .   ? 19.88370 -44.10979 -12.26681 1.000 28.08264 ? 697 HOH A O   1 
HETATM 2093 O  O   . HOH E 4 .   ? 19.23573 -4.04729  -9.79632  1.000 14.95656 ? 698 HOH A O   1 
HETATM 2094 O  O   . HOH E 4 .   ? 29.15276 -3.53888  -3.38521  1.000 13.49281 ? 699 HOH A O   1 
HETATM 2095 O  O   . HOH E 4 .   ? 11.08681 -2.81488  11.36115  1.000 19.02714 ? 700 HOH A O   1 
HETATM 2096 O  O   . HOH E 4 .   ? 14.55970 -32.31560 14.70588  1.000 25.59444 ? 701 HOH A O   1 
HETATM 2097 O  O   . HOH E 4 .   ? 11.57474 -12.64027 0.78310   1.000 11.91124 ? 702 HOH A O   1 
HETATM 2098 O  O   . HOH E 4 .   ? 11.80804 -3.38772  5.91724   1.000 17.14155 ? 703 HOH A O   1 
HETATM 2099 O  O   . HOH E 4 .   ? 9.01490  -35.84246 -0.28979  1.000 21.99826 ? 704 HOH A O   1 
HETATM 2100 O  O   . HOH E 4 .   ? 3.13892  -18.40229 -0.30826  1.000 16.04708 ? 705 HOH A O   1 
HETATM 2101 O  O   . HOH E 4 .   ? 23.56668 -30.36490 12.63634  1.000 21.82676 ? 706 HOH A O   1 
HETATM 2102 O  O   . HOH E 4 .   ? -4.65749 -19.79802 8.50301   1.000 24.05040 ? 707 HOH A O   1 
HETATM 2103 O  O   . HOH E 4 .   ? 13.13686 -5.07544  -9.64188  1.000 14.52146 ? 708 HOH A O   1 
HETATM 2104 O  O   . HOH E 4 .   ? -4.40734 -33.37714 -9.59594  1.000 24.09908 ? 709 HOH A O   1 
HETATM 2105 O  O   . HOH E 4 .   ? 26.80955 -30.61711 -17.88483 1.000 14.78987 ? 710 HOH A O   1 
HETATM 2106 O  O   . HOH E 4 .   ? -3.13069 -7.54849  -2.72732  1.000 31.45981 ? 711 HOH A O   1 
HETATM 2107 O  O   . HOH E 4 .   ? 32.83980 -25.98395 13.50945  1.000 19.44192 ? 712 HOH A O   1 
HETATM 2108 O  O   . HOH E 4 .   ? 12.61730 -37.31688 1.24502   1.000 16.06492 ? 713 HOH A O   1 
HETATM 2109 O  O   . HOH E 4 .   ? 42.57595 -16.99510 -11.61878 1.000 23.99824 ? 714 HOH A O   1 
HETATM 2110 O  O   . HOH E 4 .   ? 1.15191  -7.42119  8.95869   1.000 25.51835 ? 715 HOH A O   1 
HETATM 2111 O  O   . HOH E 4 .   ? 1.053    -23.510   -14.436   1.000 25.70958 ? 716 HOH A O   1 
HETATM 2112 O  O   . HOH E 4 .   ? 9.53114  -39.83617 -4.99507  1.000 26.77424 ? 717 HOH A O   1 
HETATM 2113 O  O   . HOH E 4 .   ? 33.33945 -30.64573 -18.42354 1.000 31.32169 ? 718 HOH A O   1 
HETATM 2114 O  O   . HOH E 4 .   ? -6.29341 -24.78853 -1.00142  1.000 25.98590 ? 719 HOH A O   1 
HETATM 2115 O  O   . HOH E 4 .   ? 30.80519 -32.17374 -17.35932 1.000 20.05506 ? 720 HOH A O   1 
HETATM 2116 O  O   . HOH E 4 .   ? 17.84161 -1.19476  -8.99791  1.000 18.82928 ? 721 HOH A O   1 
HETATM 2117 O  O   . HOH E 4 .   ? 23.09837 -33.63409 11.71074  1.000 22.10317 ? 722 HOH A O   1 
HETATM 2118 O  O   . HOH E 4 .   ? 39.46865 -20.37298 -5.90588  1.000 14.05581 ? 723 HOH A O   1 
HETATM 2119 O  O   . HOH E 4 .   ? 15.39801 -34.96110 6.88342   1.000 22.31863 ? 724 HOH A O   1 
HETATM 2120 O  O   . HOH E 4 .   ? -0.53498 -26.51956 9.54906   1.000 25.50517 ? 725 HOH A O   1 
HETATM 2121 O  O   . HOH E 4 .   ? 0.16974  -32.70989 1.94279   1.000 19.61596 ? 726 HOH A O   1 
HETATM 2122 O  O   . HOH E 4 .   ? 14.39511 -35.32555 2.50719   1.000 20.66633 ? 727 HOH A O   1 
HETATM 2123 O  O   . HOH E 4 .   ? 39.44653 -13.39886 -8.52239  1.000 29.26888 ? 728 HOH A O   1 
HETATM 2124 O  O   . HOH E 4 .   ? 6.91293  -7.63668  -1.24655  1.000 20.01679 ? 729 HOH A O   1 
HETATM 2125 O  O   . HOH E 4 .   ? 25.48534 -39.53465 -14.57611 1.000 23.07853 ? 730 HOH A O   1 
HETATM 2126 O  O   . HOH E 4 .   ? 27.60325 -14.38476 -23.31808 1.000 28.25511 ? 731 HOH A O   1 
HETATM 2127 O  O   . HOH E 4 .   ? 26.91534 -12.24145 13.09325  1.000 21.64984 ? 732 HOH A O   1 
HETATM 2128 O  O   . HOH E 4 .   ? 14.16967 -5.79895  12.55918  1.000 25.12630 ? 733 HOH A O   1 
HETATM 2129 O  O   . HOH E 4 .   ? 24.78668 -16.92967 18.62743  1.000 30.52254 ? 734 HOH A O   1 
HETATM 2130 O  O   . HOH E 4 .   ? -4.27754 -19.63523 5.23777   1.000 20.72561 ? 735 HOH A O   1 
HETATM 2131 O  O   . HOH E 4 .   ? 22.75597 -44.86408 -12.46154 1.000 30.56724 ? 736 HOH A O   1 
HETATM 2132 O  O   . HOH E 4 .   ? 36.32490 -18.33292 7.94410   1.000 28.57542 ? 737 HOH A O   1 
HETATM 2133 O  O   . HOH E 4 .   ? 21.97936 -38.56896 4.35580   1.000 22.88921 ? 738 HOH A O   1 
HETATM 2134 O  O   . HOH E 4 .   ? 9.74715  -39.35055 -14.05897 1.000 26.00927 ? 739 HOH A O   1 
HETATM 2135 O  O   . HOH E 4 .   ? 38.184   -21.181   -15.667   1.000 26.68919 ? 740 HOH A O   1 
HETATM 2136 O  O   . HOH E 4 .   ? 32.82063 -8.12026  -4.06629  1.000 25.41733 ? 741 HOH A O   1 
HETATM 2137 O  O   . HOH E 4 .   ? 41.43133 -28.25047 3.18377   1.000 32.07335 ? 742 HOH A O   1 
HETATM 2138 O  O   . HOH E 4 .   ? -0.663   -22.123   -13.633   1.000 19.44401 ? 743 HOH A O   1 
HETATM 2139 O  O   . HOH E 4 .   ? 13.83256 -28.89249 -20.19086 1.000 29.18684 ? 744 HOH A O   1 
HETATM 2140 O  O   . HOH E 4 .   ? 12.32352 -34.58534 4.34397   1.000 24.86963 ? 745 HOH A O   1 
HETATM 2141 O  O   . HOH E 4 .   ? 26.128   -7.725    -15.709   1.000 23.52093 ? 746 HOH A O   1 
HETATM 2142 O  O   . HOH E 4 .   ? 35.79638 -11.79816 -3.33045  1.000 27.27955 ? 747 HOH A O   1 
HETATM 2143 O  O   . HOH E 4 .   ? 7.38225  -38.04427 -15.70445 1.000 27.87151 ? 748 HOH A O   1 
HETATM 2144 O  O   . HOH E 4 .   ? 39.49606 -27.54042 2.10733   1.000 23.63073 ? 749 HOH A O   1 
HETATM 2145 O  O   . HOH E 4 .   ? 15.61465 -26.41325 -19.41325 1.000 38.66923 ? 750 HOH A O   1 
HETATM 2146 O  O   . HOH E 4 .   ? 15.37424 -37.45760 3.52765   1.000 21.07298 ? 751 HOH A O   1 
HETATM 2147 O  O   . HOH E 4 .   ? 32.07445 -7.28806  -6.92614  1.000 31.97147 ? 752 HOH A O   1 
HETATM 2148 O  O   . HOH E 4 .   ? 17.56764 -17.29590 22.12939  1.000 27.77129 ? 753 HOH A O   1 
HETATM 2149 O  O   . HOH E 4 .   ? 37.47153 -20.06640 11.60637  1.000 26.84467 ? 754 HOH A O   1 
HETATM 2150 O  O   . HOH E 4 .   ? 8.45849  -39.82023 -11.59471 1.000 23.63216 ? 755 HOH A O   1 
HETATM 2151 O  O   . HOH E 4 .   ? 27.66377 -11.21815 -18.85659 1.000 35.01871 ? 756 HOH A O   1 
HETATM 2152 O  O   . HOH E 4 .   ? -0.82694 -5.79216  8.73774   1.000 42.40703 ? 757 HOH A O   1 
HETATM 2153 O  O   . HOH E 4 .   ? 27.00099 -9.44282  12.74947  1.000 24.55923 ? 758 HOH A O   1 
HETATM 2154 O  O   . HOH E 4 .   ? 40.32819 -15.52043 -7.33404  1.000 31.41287 ? 759 HOH A O   1 
HETATM 2155 O  O   . HOH E 4 .   ? 21.653   -1.942    10.988    1.000 27.47561 ? 760 HOH A O   1 
HETATM 2156 O  O   . HOH E 4 .   ? 29.65762 -12.14528 -19.50366 1.000 30.06886 ? 761 HOH A O   1 
HETATM 2157 O  O   . HOH E 4 .   ? 15.94150 -16.76197 23.80862  1.000 31.19521 ? 762 HOH A O   1 
HETATM 2158 O  O   . HOH E 4 .   ? -5.65655 -17.03556 5.29876   1.000 24.20509 ? 763 HOH A O   1 
HETATM 2159 O  O   . HOH E 4 .   ? -4.58253 -9.54668  6.33921   1.000 28.09082 ? 764 HOH A O   1 
HETATM 2160 O  O   . HOH E 4 .   ? 11.66539 -15.13570 -15.04685 1.000 32.49464 ? 765 HOH A O   1 
HETATM 2161 O  O   . HOH E 4 .   ? 11.50237 -39.61014 -0.18847  1.000 23.70324 ? 766 HOH A O   1 
HETATM 2162 O  O   . HOH E 4 .   ? 41.42777 -13.11930 -5.62220  1.000 30.45450 ? 767 HOH A O   1 
HETATM 2163 O  O   . HOH E 4 .   ? 11.89129 -40.51005 -5.01719  1.000 31.20448 ? 768 HOH A O   1 
HETATM 2164 O  O   . HOH E 4 .   ? 16.66928 -17.71949 -14.16634 1.000 31.75737 ? 769 HOH A O   1 
HETATM 2165 O  O   . HOH E 4 .   ? 25.56197 -14.20419 18.19414  1.000 27.63421 ? 770 HOH A O   1 
HETATM 2166 O  O   . HOH E 4 .   ? -7.28942 -15.65900 4.52095   1.000 33.02297 ? 771 HOH A O   1 
HETATM 2167 O  O   . HOH E 4 .   ? 22.32563 -12.92077 -24.14676 1.000 30.23158 ? 772 HOH A O   1 
HETATM 2168 O  O   . HOH E 4 .   ? 23.15552 -11.08378 -25.28104 1.000 28.97655 ? 773 HOH A O   1 
# 
