data_9FS3
# 
_entry.id   9FS3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FS3         pdb_00009fs3 10.2210/pdb9fs3/pdb 
WWPDB D_1292138959 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-12-04 
2 'Structure model' 1 1 2024-12-11 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Structure summary' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            struct 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_struct.title' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FS3 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              sramon@ibv.csic.es 
_pdbx_contact_author.name_first         Santiago 
_pdbx_contact_author.name_last          Ramon-Maiques 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9674-8088 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'del Cano-Ochoa, F.' 1 0000-0003-3093-3103 
'Ramon-Maiques, S.'  2 0000-0001-9674-8088 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Mol.Biol. 
_citation.journal_id_ASTM           JMOBAK 
_citation.journal_id_CSD            0070 
_citation.journal_id_ISSN           1089-8638 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            436 
_citation.language                  ? 
_citation.page_first                168832 
_citation.page_last                 168832 
_citation.title                     'Disruption of CAD Oligomerization by Pathogenic Variants.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jmb.2024.168832 
_citation.pdbx_database_id_PubMed   39447673 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Del Cano-Ochoa, F.'    1 ? 
primary 'Ramadane-Morchadi, L.' 2 ? 
primary 'Eixeres, L.'           3 ? 
primary 'Moreno-Morcillo, M.'   4 ? 
primary 'Fernandez-Leiro, R.'   5 ? 
primary 'Ramon-Maiques, S.'     6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Multifunctional protein CAD' 39678.430 1   6.3.5.5,3.5.1.2,6.3.4.16,2.1.3.2,3.5.2.3 S1538A ? ? 
2 non-polymer syn 'FORMIC ACID'                 46.025    9   ?                                        ?      ? ? 
3 non-polymer syn 'ZINC ION'                    65.409    4   ?                                        ?      ? ? 
4 non-polymer syn GLYCEROL                      92.094    1   ?                                        ?      ? ? 
5 non-polymer syn 'SODIUM ION'                  22.990    1   ?                                        ?      ? ? 
6 water       nat water                         18.015    441 ?                                        ?      ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;KLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGAAS
ENAGTLGTVAGSAAGL(KCX)LYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHV
ARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEK
CGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFE
GQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;KLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGAAS
ENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKE
EILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSR
PPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKV
KGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLP
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FORMIC ACID' FMT 
3 'ZINC ION'    ZN  
4 GLYCEROL      GOL 
5 'SODIUM ION'  NA  
6 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LYS n 
1 2   LEU n 
1 3   VAL n 
1 4   ARG n 
1 5   LEU n 
1 6   PRO n 
1 7   GLY n 
1 8   LEU n 
1 9   ILE n 
1 10  ASP n 
1 11  VAL n 
1 12  HIS n 
1 13  VAL n 
1 14  HIS n 
1 15  LEU n 
1 16  ARG n 
1 17  GLU n 
1 18  PRO n 
1 19  GLY n 
1 20  GLY n 
1 21  THR n 
1 22  HIS n 
1 23  LYS n 
1 24  GLU n 
1 25  ASP n 
1 26  PHE n 
1 27  ALA n 
1 28  SER n 
1 29  GLY n 
1 30  THR n 
1 31  ALA n 
1 32  ALA n 
1 33  ALA n 
1 34  LEU n 
1 35  ALA n 
1 36  GLY n 
1 37  GLY n 
1 38  ILE n 
1 39  THR n 
1 40  MET n 
1 41  VAL n 
1 42  CYS n 
1 43  ALA n 
1 44  MET n 
1 45  PRO n 
1 46  ASN n 
1 47  THR n 
1 48  ARG n 
1 49  PRO n 
1 50  PRO n 
1 51  ILE n 
1 52  ILE n 
1 53  ASP n 
1 54  ALA n 
1 55  PRO n 
1 56  ALA n 
1 57  LEU n 
1 58  ALA n 
1 59  LEU n 
1 60  ALA n 
1 61  GLN n 
1 62  LYS n 
1 63  LEU n 
1 64  ALA n 
1 65  GLU n 
1 66  ALA n 
1 67  GLY n 
1 68  ALA n 
1 69  ARG n 
1 70  CYS n 
1 71  ASP n 
1 72  PHE n 
1 73  ALA n 
1 74  LEU n 
1 75  PHE n 
1 76  LEU n 
1 77  GLY n 
1 78  ALA n 
1 79  ALA n 
1 80  SER n 
1 81  GLU n 
1 82  ASN n 
1 83  ALA n 
1 84  GLY n 
1 85  THR n 
1 86  LEU n 
1 87  GLY n 
1 88  THR n 
1 89  VAL n 
1 90  ALA n 
1 91  GLY n 
1 92  SER n 
1 93  ALA n 
1 94  ALA n 
1 95  GLY n 
1 96  LEU n 
1 97  KCX n 
1 98  LEU n 
1 99  TYR n 
1 100 LEU n 
1 101 ASN n 
1 102 GLU n 
1 103 THR n 
1 104 PHE n 
1 105 SER n 
1 106 GLU n 
1 107 LEU n 
1 108 ARG n 
1 109 LEU n 
1 110 ASP n 
1 111 SER n 
1 112 VAL n 
1 113 VAL n 
1 114 GLN n 
1 115 TRP n 
1 116 MET n 
1 117 GLU n 
1 118 HIS n 
1 119 PHE n 
1 120 GLU n 
1 121 THR n 
1 122 TRP n 
1 123 PRO n 
1 124 SER n 
1 125 HIS n 
1 126 LEU n 
1 127 PRO n 
1 128 ILE n 
1 129 VAL n 
1 130 ALA n 
1 131 HIS n 
1 132 ALA n 
1 133 GLU n 
1 134 GLN n 
1 135 GLN n 
1 136 THR n 
1 137 VAL n 
1 138 ALA n 
1 139 ALA n 
1 140 VAL n 
1 141 LEU n 
1 142 MET n 
1 143 VAL n 
1 144 ALA n 
1 145 GLN n 
1 146 LEU n 
1 147 THR n 
1 148 GLN n 
1 149 ARG n 
1 150 SER n 
1 151 VAL n 
1 152 HIS n 
1 153 ILE n 
1 154 CYS n 
1 155 HIS n 
1 156 VAL n 
1 157 ALA n 
1 158 ARG n 
1 159 LYS n 
1 160 GLU n 
1 161 GLU n 
1 162 ILE n 
1 163 LEU n 
1 164 LEU n 
1 165 ILE n 
1 166 LYS n 
1 167 ALA n 
1 168 ALA n 
1 169 LYS n 
1 170 ALA n 
1 171 ARG n 
1 172 GLY n 
1 173 LEU n 
1 174 PRO n 
1 175 VAL n 
1 176 THR n 
1 177 CYS n 
1 178 GLU n 
1 179 VAL n 
1 180 ALA n 
1 181 PRO n 
1 182 HIS n 
1 183 HIS n 
1 184 LEU n 
1 185 PHE n 
1 186 LEU n 
1 187 SER n 
1 188 HIS n 
1 189 ASP n 
1 190 ASP n 
1 191 LEU n 
1 192 GLU n 
1 193 ARG n 
1 194 LEU n 
1 195 GLY n 
1 196 PRO n 
1 197 GLY n 
1 198 LYS n 
1 199 GLY n 
1 200 GLU n 
1 201 VAL n 
1 202 ARG n 
1 203 PRO n 
1 204 GLU n 
1 205 LEU n 
1 206 GLY n 
1 207 SER n 
1 208 ARG n 
1 209 GLN n 
1 210 ASP n 
1 211 VAL n 
1 212 GLU n 
1 213 ALA n 
1 214 LEU n 
1 215 TRP n 
1 216 GLU n 
1 217 ASN n 
1 218 MET n 
1 219 ALA n 
1 220 VAL n 
1 221 ILE n 
1 222 ASP n 
1 223 CYS n 
1 224 PHE n 
1 225 ALA n 
1 226 SER n 
1 227 ASP n 
1 228 HIS n 
1 229 ALA n 
1 230 PRO n 
1 231 HIS n 
1 232 THR n 
1 233 LEU n 
1 234 GLU n 
1 235 GLU n 
1 236 LYS n 
1 237 CYS n 
1 238 GLY n 
1 239 SER n 
1 240 ARG n 
1 241 PRO n 
1 242 PRO n 
1 243 PRO n 
1 244 GLY n 
1 245 PHE n 
1 246 PRO n 
1 247 GLY n 
1 248 LEU n 
1 249 GLU n 
1 250 THR n 
1 251 MET n 
1 252 LEU n 
1 253 PRO n 
1 254 LEU n 
1 255 LEU n 
1 256 LEU n 
1 257 THR n 
1 258 ALA n 
1 259 VAL n 
1 260 SER n 
1 261 GLU n 
1 262 GLY n 
1 263 ARG n 
1 264 LEU n 
1 265 SER n 
1 266 LEU n 
1 267 ASP n 
1 268 ASP n 
1 269 LEU n 
1 270 LEU n 
1 271 GLN n 
1 272 ARG n 
1 273 LEU n 
1 274 HIS n 
1 275 HIS n 
1 276 ASN n 
1 277 PRO n 
1 278 ARG n 
1 279 ARG n 
1 280 ILE n 
1 281 PHE n 
1 282 HIS n 
1 283 LEU n 
1 284 PRO n 
1 285 PRO n 
1 286 GLN n 
1 287 GLU n 
1 288 ASP n 
1 289 THR n 
1 290 TYR n 
1 291 VAL n 
1 292 GLU n 
1 293 VAL n 
1 294 ASP n 
1 295 LEU n 
1 296 GLU n 
1 297 HIS n 
1 298 GLU n 
1 299 TRP n 
1 300 THR n 
1 301 ILE n 
1 302 PRO n 
1 303 SER n 
1 304 HIS n 
1 305 MET n 
1 306 PRO n 
1 307 PHE n 
1 308 SER n 
1 309 LYS n 
1 310 ALA n 
1 311 HIS n 
1 312 TRP n 
1 313 THR n 
1 314 PRO n 
1 315 PHE n 
1 316 GLU n 
1 317 GLY n 
1 318 GLN n 
1 319 LYS n 
1 320 VAL n 
1 321 LYS n 
1 322 GLY n 
1 323 THR n 
1 324 VAL n 
1 325 ARG n 
1 326 ARG n 
1 327 VAL n 
1 328 VAL n 
1 329 LEU n 
1 330 ARG n 
1 331 GLY n 
1 332 GLU n 
1 333 VAL n 
1 334 ALA n 
1 335 TYR n 
1 336 ILE n 
1 337 ASP n 
1 338 GLY n 
1 339 GLN n 
1 340 VAL n 
1 341 LEU n 
1 342 VAL n 
1 343 PRO n 
1 344 PRO n 
1 345 GLY n 
1 346 TYR n 
1 347 GLY n 
1 348 GLN n 
1 349 ASP n 
1 350 VAL n 
1 351 ARG n 
1 352 LYS n 
1 353 TRP n 
1 354 PRO n 
1 355 GLN n 
1 356 GLY n 
1 357 ALA n 
1 358 VAL n 
1 359 PRO n 
1 360 GLN n 
1 361 LEU n 
1 362 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   362 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 CAD 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                Embryo 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               kidney 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK293S-GnTI 
_entity_src_gen.pdbx_host_org_atcc                 CRL-3022 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 epithelial-like 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pOPIN-M-huDHO-S1538A 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                    ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                    ?                               'C3 H7 N O2 S'   121.158 
FMT non-polymer         . 'FORMIC ACID'               ?                               'C H2 O2'        46.025  
GLN 'L-peptide linking' y GLUTAMINE                   ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                     ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                    'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                   ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                       ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                  ?                               'C6 H13 N O2'    131.173 
KCX 'L-peptide linking' n 'LYSINE NZ-CARBOXYLIC ACID' ?                               'C7 H14 N2 O4'   190.197 
LEU 'L-peptide linking' y LEUCINE                     ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                      ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                  ?                               'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'                ?                               'Na 1'           22.990  
PHE 'L-peptide linking' y PHENYLALANINE               ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                     ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                      ?                               'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                   ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                      ?                               'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'                  ?                               'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LYS 1   1460 1460 LYS LYS A . n 
A 1 2   LEU 2   1461 1461 LEU LEU A . n 
A 1 3   VAL 3   1462 1462 VAL VAL A . n 
A 1 4   ARG 4   1463 1463 ARG ARG A . n 
A 1 5   LEU 5   1464 1464 LEU LEU A . n 
A 1 6   PRO 6   1465 1465 PRO PRO A . n 
A 1 7   GLY 7   1466 1466 GLY GLY A . n 
A 1 8   LEU 8   1467 1467 LEU LEU A . n 
A 1 9   ILE 9   1468 1468 ILE ILE A . n 
A 1 10  ASP 10  1469 1469 ASP ASP A . n 
A 1 11  VAL 11  1470 1470 VAL VAL A . n 
A 1 12  HIS 12  1471 1471 HIS HIS A . n 
A 1 13  VAL 13  1472 1472 VAL VAL A . n 
A 1 14  HIS 14  1473 1473 HIS HIS A . n 
A 1 15  LEU 15  1474 1474 LEU LEU A . n 
A 1 16  ARG 16  1475 1475 ARG ARG A . n 
A 1 17  GLU 17  1476 1476 GLU GLU A . n 
A 1 18  PRO 18  1477 1477 PRO PRO A . n 
A 1 19  GLY 19  1478 1478 GLY GLY A . n 
A 1 20  GLY 20  1479 1479 GLY GLY A . n 
A 1 21  THR 21  1480 1480 THR THR A . n 
A 1 22  HIS 22  1481 1481 HIS HIS A . n 
A 1 23  LYS 23  1482 1482 LYS LYS A . n 
A 1 24  GLU 24  1483 1483 GLU GLU A . n 
A 1 25  ASP 25  1484 1484 ASP ASP A . n 
A 1 26  PHE 26  1485 1485 PHE PHE A . n 
A 1 27  ALA 27  1486 1486 ALA ALA A . n 
A 1 28  SER 28  1487 1487 SER SER A . n 
A 1 29  GLY 29  1488 1488 GLY GLY A . n 
A 1 30  THR 30  1489 1489 THR THR A . n 
A 1 31  ALA 31  1490 1490 ALA ALA A . n 
A 1 32  ALA 32  1491 1491 ALA ALA A . n 
A 1 33  ALA 33  1492 1492 ALA ALA A . n 
A 1 34  LEU 34  1493 1493 LEU LEU A . n 
A 1 35  ALA 35  1494 1494 ALA ALA A . n 
A 1 36  GLY 36  1495 1495 GLY GLY A . n 
A 1 37  GLY 37  1496 1496 GLY GLY A . n 
A 1 38  ILE 38  1497 1497 ILE ILE A . n 
A 1 39  THR 39  1498 1498 THR THR A . n 
A 1 40  MET 40  1499 1499 MET MET A . n 
A 1 41  VAL 41  1500 1500 VAL VAL A . n 
A 1 42  CYS 42  1501 1501 CYS CYS A . n 
A 1 43  ALA 43  1502 1502 ALA ALA A . n 
A 1 44  MET 44  1503 1503 MET MET A . n 
A 1 45  PRO 45  1504 1504 PRO PRO A . n 
A 1 46  ASN 46  1505 1505 ASN ASN A . n 
A 1 47  THR 47  1506 1506 THR THR A . n 
A 1 48  ARG 48  1507 1507 ARG ARG A . n 
A 1 49  PRO 49  1508 1508 PRO PRO A . n 
A 1 50  PRO 50  1509 1509 PRO PRO A . n 
A 1 51  ILE 51  1510 1510 ILE ILE A . n 
A 1 52  ILE 52  1511 1511 ILE ILE A . n 
A 1 53  ASP 53  1512 1512 ASP ASP A . n 
A 1 54  ALA 54  1513 1513 ALA ALA A . n 
A 1 55  PRO 55  1514 1514 PRO PRO A . n 
A 1 56  ALA 56  1515 1515 ALA ALA A . n 
A 1 57  LEU 57  1516 1516 LEU LEU A . n 
A 1 58  ALA 58  1517 1517 ALA ALA A . n 
A 1 59  LEU 59  1518 1518 LEU LEU A . n 
A 1 60  ALA 60  1519 1519 ALA ALA A . n 
A 1 61  GLN 61  1520 1520 GLN GLN A . n 
A 1 62  LYS 62  1521 1521 LYS LYS A . n 
A 1 63  LEU 63  1522 1522 LEU LEU A . n 
A 1 64  ALA 64  1523 1523 ALA ALA A . n 
A 1 65  GLU 65  1524 1524 GLU GLU A . n 
A 1 66  ALA 66  1525 1525 ALA ALA A . n 
A 1 67  GLY 67  1526 1526 GLY GLY A . n 
A 1 68  ALA 68  1527 1527 ALA ALA A . n 
A 1 69  ARG 69  1528 1528 ARG ARG A . n 
A 1 70  CYS 70  1529 1529 CYS CYS A . n 
A 1 71  ASP 71  1530 1530 ASP ASP A . n 
A 1 72  PHE 72  1531 1531 PHE PHE A . n 
A 1 73  ALA 73  1532 1532 ALA ALA A . n 
A 1 74  LEU 74  1533 1533 LEU LEU A . n 
A 1 75  PHE 75  1534 1534 PHE PHE A . n 
A 1 76  LEU 76  1535 1535 LEU LEU A . n 
A 1 77  GLY 77  1536 1536 GLY GLY A . n 
A 1 78  ALA 78  1537 1537 ALA ALA A . n 
A 1 79  ALA 79  1538 1538 ALA ALA A . n 
A 1 80  SER 80  1539 1539 SER SER A . n 
A 1 81  GLU 81  1540 1540 GLU GLU A . n 
A 1 82  ASN 82  1541 1541 ASN ASN A . n 
A 1 83  ALA 83  1542 1542 ALA ALA A . n 
A 1 84  GLY 84  1543 1543 GLY GLY A . n 
A 1 85  THR 85  1544 1544 THR THR A . n 
A 1 86  LEU 86  1545 1545 LEU LEU A . n 
A 1 87  GLY 87  1546 1546 GLY GLY A . n 
A 1 88  THR 88  1547 1547 THR THR A . n 
A 1 89  VAL 89  1548 1548 VAL VAL A . n 
A 1 90  ALA 90  1549 1549 ALA ALA A . n 
A 1 91  GLY 91  1550 1550 GLY GLY A . n 
A 1 92  SER 92  1551 1551 SER SER A . n 
A 1 93  ALA 93  1552 1552 ALA ALA A . n 
A 1 94  ALA 94  1553 1553 ALA ALA A . n 
A 1 95  GLY 95  1554 1554 GLY GLY A . n 
A 1 96  LEU 96  1555 1555 LEU LEU A . n 
A 1 97  KCX 97  1556 1556 KCX KCX A . n 
A 1 98  LEU 98  1557 1557 LEU LEU A . n 
A 1 99  TYR 99  1558 1558 TYR TYR A . n 
A 1 100 LEU 100 1559 1559 LEU LEU A . n 
A 1 101 ASN 101 1560 1560 ASN ASN A . n 
A 1 102 GLU 102 1561 1561 GLU GLU A . n 
A 1 103 THR 103 1562 1562 THR THR A . n 
A 1 104 PHE 104 1563 1563 PHE PHE A . n 
A 1 105 SER 105 1564 1564 SER SER A . n 
A 1 106 GLU 106 1565 1565 GLU GLU A . n 
A 1 107 LEU 107 1566 1566 LEU LEU A . n 
A 1 108 ARG 108 1567 1567 ARG ARG A . n 
A 1 109 LEU 109 1568 1568 LEU LEU A . n 
A 1 110 ASP 110 1569 1569 ASP ASP A . n 
A 1 111 SER 111 1570 1570 SER SER A . n 
A 1 112 VAL 112 1571 1571 VAL VAL A . n 
A 1 113 VAL 113 1572 1572 VAL VAL A . n 
A 1 114 GLN 114 1573 1573 GLN GLN A . n 
A 1 115 TRP 115 1574 1574 TRP TRP A . n 
A 1 116 MET 116 1575 1575 MET MET A . n 
A 1 117 GLU 117 1576 1576 GLU GLU A . n 
A 1 118 HIS 118 1577 1577 HIS HIS A . n 
A 1 119 PHE 119 1578 1578 PHE PHE A . n 
A 1 120 GLU 120 1579 1579 GLU GLU A . n 
A 1 121 THR 121 1580 1580 THR THR A . n 
A 1 122 TRP 122 1581 1581 TRP TRP A . n 
A 1 123 PRO 123 1582 1582 PRO PRO A . n 
A 1 124 SER 124 1583 1583 SER SER A . n 
A 1 125 HIS 125 1584 1584 HIS HIS A . n 
A 1 126 LEU 126 1585 1585 LEU LEU A . n 
A 1 127 PRO 127 1586 1586 PRO PRO A . n 
A 1 128 ILE 128 1587 1587 ILE ILE A . n 
A 1 129 VAL 129 1588 1588 VAL VAL A . n 
A 1 130 ALA 130 1589 1589 ALA ALA A . n 
A 1 131 HIS 131 1590 1590 HIS HIS A . n 
A 1 132 ALA 132 1591 1591 ALA ALA A . n 
A 1 133 GLU 133 1592 1592 GLU GLU A . n 
A 1 134 GLN 134 1593 1593 GLN GLN A . n 
A 1 135 GLN 135 1594 1594 GLN GLN A . n 
A 1 136 THR 136 1595 1595 THR THR A . n 
A 1 137 VAL 137 1596 1596 VAL VAL A . n 
A 1 138 ALA 138 1597 1597 ALA ALA A . n 
A 1 139 ALA 139 1598 1598 ALA ALA A . n 
A 1 140 VAL 140 1599 1599 VAL VAL A . n 
A 1 141 LEU 141 1600 1600 LEU LEU A . n 
A 1 142 MET 142 1601 1601 MET MET A . n 
A 1 143 VAL 143 1602 1602 VAL VAL A . n 
A 1 144 ALA 144 1603 1603 ALA ALA A . n 
A 1 145 GLN 145 1604 1604 GLN GLN A . n 
A 1 146 LEU 146 1605 1605 LEU LEU A . n 
A 1 147 THR 147 1606 1606 THR THR A . n 
A 1 148 GLN 148 1607 1607 GLN GLN A . n 
A 1 149 ARG 149 1608 1608 ARG ARG A . n 
A 1 150 SER 150 1609 1609 SER SER A . n 
A 1 151 VAL 151 1610 1610 VAL VAL A . n 
A 1 152 HIS 152 1611 1611 HIS HIS A . n 
A 1 153 ILE 153 1612 1612 ILE ILE A . n 
A 1 154 CYS 154 1613 1613 CYS CYS A . n 
A 1 155 HIS 155 1614 1614 HIS HIS A . n 
A 1 156 VAL 156 1615 1615 VAL VAL A . n 
A 1 157 ALA 157 1616 1616 ALA ALA A . n 
A 1 158 ARG 158 1617 1617 ARG ARG A . n 
A 1 159 LYS 159 1618 1618 LYS LYS A . n 
A 1 160 GLU 160 1619 1619 GLU GLU A . n 
A 1 161 GLU 161 1620 1620 GLU GLU A . n 
A 1 162 ILE 162 1621 1621 ILE ILE A . n 
A 1 163 LEU 163 1622 1622 LEU LEU A . n 
A 1 164 LEU 164 1623 1623 LEU LEU A . n 
A 1 165 ILE 165 1624 1624 ILE ILE A . n 
A 1 166 LYS 166 1625 1625 LYS LYS A . n 
A 1 167 ALA 167 1626 1626 ALA ALA A . n 
A 1 168 ALA 168 1627 1627 ALA ALA A . n 
A 1 169 LYS 169 1628 1628 LYS LYS A . n 
A 1 170 ALA 170 1629 1629 ALA ALA A . n 
A 1 171 ARG 171 1630 1630 ARG ARG A . n 
A 1 172 GLY 172 1631 1631 GLY GLY A . n 
A 1 173 LEU 173 1632 1632 LEU LEU A . n 
A 1 174 PRO 174 1633 1633 PRO PRO A . n 
A 1 175 VAL 175 1634 1634 VAL VAL A . n 
A 1 176 THR 176 1635 1635 THR THR A . n 
A 1 177 CYS 177 1636 1636 CYS CYS A . n 
A 1 178 GLU 178 1637 1637 GLU GLU A . n 
A 1 179 VAL 179 1638 1638 VAL VAL A . n 
A 1 180 ALA 180 1639 1639 ALA ALA A . n 
A 1 181 PRO 181 1640 1640 PRO PRO A . n 
A 1 182 HIS 182 1641 1641 HIS HIS A . n 
A 1 183 HIS 183 1642 1642 HIS HIS A . n 
A 1 184 LEU 184 1643 1643 LEU LEU A . n 
A 1 185 PHE 185 1644 1644 PHE PHE A . n 
A 1 186 LEU 186 1645 1645 LEU LEU A . n 
A 1 187 SER 187 1646 1646 SER SER A . n 
A 1 188 HIS 188 1647 1647 HIS HIS A . n 
A 1 189 ASP 189 1648 1648 ASP ASP A . n 
A 1 190 ASP 190 1649 1649 ASP ASP A . n 
A 1 191 LEU 191 1650 1650 LEU LEU A . n 
A 1 192 GLU 192 1651 1651 GLU GLU A . n 
A 1 193 ARG 193 1652 1652 ARG ARG A . n 
A 1 194 LEU 194 1653 1653 LEU LEU A . n 
A 1 195 GLY 195 1654 1654 GLY GLY A . n 
A 1 196 PRO 196 1655 1655 PRO PRO A . n 
A 1 197 GLY 197 1656 1656 GLY GLY A . n 
A 1 198 LYS 198 1657 1657 LYS LYS A . n 
A 1 199 GLY 199 1658 1658 GLY GLY A . n 
A 1 200 GLU 200 1659 1659 GLU GLU A . n 
A 1 201 VAL 201 1660 1660 VAL VAL A . n 
A 1 202 ARG 202 1661 1661 ARG ARG A . n 
A 1 203 PRO 203 1662 1662 PRO PRO A . n 
A 1 204 GLU 204 1663 1663 GLU GLU A . n 
A 1 205 LEU 205 1664 1664 LEU LEU A . n 
A 1 206 GLY 206 1665 1665 GLY GLY A . n 
A 1 207 SER 207 1666 1666 SER SER A . n 
A 1 208 ARG 208 1667 1667 ARG ARG A . n 
A 1 209 GLN 209 1668 1668 GLN GLN A . n 
A 1 210 ASP 210 1669 1669 ASP ASP A . n 
A 1 211 VAL 211 1670 1670 VAL VAL A . n 
A 1 212 GLU 212 1671 1671 GLU GLU A . n 
A 1 213 ALA 213 1672 1672 ALA ALA A . n 
A 1 214 LEU 214 1673 1673 LEU LEU A . n 
A 1 215 TRP 215 1674 1674 TRP TRP A . n 
A 1 216 GLU 216 1675 1675 GLU GLU A . n 
A 1 217 ASN 217 1676 1676 ASN ASN A . n 
A 1 218 MET 218 1677 1677 MET MET A . n 
A 1 219 ALA 219 1678 1678 ALA ALA A . n 
A 1 220 VAL 220 1679 1679 VAL VAL A . n 
A 1 221 ILE 221 1680 1680 ILE ILE A . n 
A 1 222 ASP 222 1681 1681 ASP ASP A . n 
A 1 223 CYS 223 1682 1682 CYS CYS A . n 
A 1 224 PHE 224 1683 1683 PHE PHE A . n 
A 1 225 ALA 225 1684 1684 ALA ALA A . n 
A 1 226 SER 226 1685 1685 SER SER A . n 
A 1 227 ASP 227 1686 1686 ASP ASP A . n 
A 1 228 HIS 228 1687 1687 HIS HIS A . n 
A 1 229 ALA 229 1688 1688 ALA ALA A . n 
A 1 230 PRO 230 1689 1689 PRO PRO A . n 
A 1 231 HIS 231 1690 1690 HIS HIS A . n 
A 1 232 THR 232 1691 1691 THR THR A . n 
A 1 233 LEU 233 1692 1692 LEU LEU A . n 
A 1 234 GLU 234 1693 1693 GLU GLU A . n 
A 1 235 GLU 235 1694 1694 GLU GLU A . n 
A 1 236 LYS 236 1695 1695 LYS LYS A . n 
A 1 237 CYS 237 1696 1696 CYS CYS A . n 
A 1 238 GLY 238 1697 1697 GLY GLY A . n 
A 1 239 SER 239 1698 1698 SER SER A . n 
A 1 240 ARG 240 1699 1699 ARG ARG A . n 
A 1 241 PRO 241 1700 1700 PRO PRO A . n 
A 1 242 PRO 242 1701 1701 PRO PRO A . n 
A 1 243 PRO 243 1702 1702 PRO PRO A . n 
A 1 244 GLY 244 1703 1703 GLY GLY A . n 
A 1 245 PHE 245 1704 1704 PHE PHE A . n 
A 1 246 PRO 246 1705 1705 PRO PRO A . n 
A 1 247 GLY 247 1706 1706 GLY GLY A . n 
A 1 248 LEU 248 1707 1707 LEU LEU A . n 
A 1 249 GLU 249 1708 1708 GLU GLU A . n 
A 1 250 THR 250 1709 1709 THR THR A . n 
A 1 251 MET 251 1710 1710 MET MET A . n 
A 1 252 LEU 252 1711 1711 LEU LEU A . n 
A 1 253 PRO 253 1712 1712 PRO PRO A . n 
A 1 254 LEU 254 1713 1713 LEU LEU A . n 
A 1 255 LEU 255 1714 1714 LEU LEU A . n 
A 1 256 LEU 256 1715 1715 LEU LEU A . n 
A 1 257 THR 257 1716 1716 THR THR A . n 
A 1 258 ALA 258 1717 1717 ALA ALA A . n 
A 1 259 VAL 259 1718 1718 VAL VAL A . n 
A 1 260 SER 260 1719 1719 SER SER A . n 
A 1 261 GLU 261 1720 1720 GLU GLU A . n 
A 1 262 GLY 262 1721 1721 GLY GLY A . n 
A 1 263 ARG 263 1722 1722 ARG ARG A . n 
A 1 264 LEU 264 1723 1723 LEU LEU A . n 
A 1 265 SER 265 1724 1724 SER SER A . n 
A 1 266 LEU 266 1725 1725 LEU LEU A . n 
A 1 267 ASP 267 1726 1726 ASP ASP A . n 
A 1 268 ASP 268 1727 1727 ASP ASP A . n 
A 1 269 LEU 269 1728 1728 LEU LEU A . n 
A 1 270 LEU 270 1729 1729 LEU LEU A . n 
A 1 271 GLN 271 1730 1730 GLN GLN A . n 
A 1 272 ARG 272 1731 1731 ARG ARG A . n 
A 1 273 LEU 273 1732 1732 LEU LEU A . n 
A 1 274 HIS 274 1733 1733 HIS HIS A . n 
A 1 275 HIS 275 1734 1734 HIS HIS A . n 
A 1 276 ASN 276 1735 1735 ASN ASN A . n 
A 1 277 PRO 277 1736 1736 PRO PRO A . n 
A 1 278 ARG 278 1737 1737 ARG ARG A . n 
A 1 279 ARG 279 1738 1738 ARG ARG A . n 
A 1 280 ILE 280 1739 1739 ILE ILE A . n 
A 1 281 PHE 281 1740 1740 PHE PHE A . n 
A 1 282 HIS 282 1741 1741 HIS HIS A . n 
A 1 283 LEU 283 1742 1742 LEU LEU A . n 
A 1 284 PRO 284 1743 1743 PRO PRO A . n 
A 1 285 PRO 285 1744 1744 PRO PRO A . n 
A 1 286 GLN 286 1745 1745 GLN GLN A . n 
A 1 287 GLU 287 1746 1746 GLU GLU A . n 
A 1 288 ASP 288 1747 1747 ASP ASP A . n 
A 1 289 THR 289 1748 1748 THR THR A . n 
A 1 290 TYR 290 1749 1749 TYR TYR A . n 
A 1 291 VAL 291 1750 1750 VAL VAL A . n 
A 1 292 GLU 292 1751 1751 GLU GLU A . n 
A 1 293 VAL 293 1752 1752 VAL VAL A . n 
A 1 294 ASP 294 1753 1753 ASP ASP A . n 
A 1 295 LEU 295 1754 1754 LEU LEU A . n 
A 1 296 GLU 296 1755 1755 GLU GLU A . n 
A 1 297 HIS 297 1756 1756 HIS HIS A . n 
A 1 298 GLU 298 1757 1757 GLU GLU A . n 
A 1 299 TRP 299 1758 1758 TRP TRP A . n 
A 1 300 THR 300 1759 1759 THR THR A . n 
A 1 301 ILE 301 1760 1760 ILE ILE A . n 
A 1 302 PRO 302 1761 1761 PRO PRO A . n 
A 1 303 SER 303 1762 1762 SER SER A . n 
A 1 304 HIS 304 1763 1763 HIS HIS A . n 
A 1 305 MET 305 1764 1764 MET MET A . n 
A 1 306 PRO 306 1765 1765 PRO PRO A . n 
A 1 307 PHE 307 1766 1766 PHE PHE A . n 
A 1 308 SER 308 1767 1767 SER SER A . n 
A 1 309 LYS 309 1768 1768 LYS LYS A . n 
A 1 310 ALA 310 1769 1769 ALA ALA A . n 
A 1 311 HIS 311 1770 1770 HIS HIS A . n 
A 1 312 TRP 312 1771 1771 TRP TRP A . n 
A 1 313 THR 313 1772 1772 THR THR A . n 
A 1 314 PRO 314 1773 1773 PRO PRO A . n 
A 1 315 PHE 315 1774 1774 PHE PHE A . n 
A 1 316 GLU 316 1775 1775 GLU GLU A . n 
A 1 317 GLY 317 1776 1776 GLY GLY A . n 
A 1 318 GLN 318 1777 1777 GLN GLN A . n 
A 1 319 LYS 319 1778 1778 LYS LYS A . n 
A 1 320 VAL 320 1779 1779 VAL VAL A . n 
A 1 321 LYS 321 1780 1780 LYS LYS A . n 
A 1 322 GLY 322 1781 1781 GLY GLY A . n 
A 1 323 THR 323 1782 1782 THR THR A . n 
A 1 324 VAL 324 1783 1783 VAL VAL A . n 
A 1 325 ARG 325 1784 1784 ARG ARG A . n 
A 1 326 ARG 326 1785 1785 ARG ARG A . n 
A 1 327 VAL 327 1786 1786 VAL VAL A . n 
A 1 328 VAL 328 1787 1787 VAL VAL A . n 
A 1 329 LEU 329 1788 1788 LEU LEU A . n 
A 1 330 ARG 330 1789 1789 ARG ARG A . n 
A 1 331 GLY 331 1790 1790 GLY GLY A . n 
A 1 332 GLU 332 1791 1791 GLU GLU A . n 
A 1 333 VAL 333 1792 1792 VAL VAL A . n 
A 1 334 ALA 334 1793 1793 ALA ALA A . n 
A 1 335 TYR 335 1794 1794 TYR TYR A . n 
A 1 336 ILE 336 1795 1795 ILE ILE A . n 
A 1 337 ASP 337 1796 1796 ASP ASP A . n 
A 1 338 GLY 338 1797 1797 GLY GLY A . n 
A 1 339 GLN 339 1798 1798 GLN GLN A . n 
A 1 340 VAL 340 1799 1799 VAL VAL A . n 
A 1 341 LEU 341 1800 1800 LEU LEU A . n 
A 1 342 VAL 342 1801 1801 VAL VAL A . n 
A 1 343 PRO 343 1802 1802 PRO PRO A . n 
A 1 344 PRO 344 1803 1803 PRO PRO A . n 
A 1 345 GLY 345 1804 1804 GLY GLY A . n 
A 1 346 TYR 346 1805 1805 TYR TYR A . n 
A 1 347 GLY 347 1806 1806 GLY GLY A . n 
A 1 348 GLN 348 1807 1807 GLN GLN A . n 
A 1 349 ASP 349 1808 1808 ASP ASP A . n 
A 1 350 VAL 350 1809 1809 VAL VAL A . n 
A 1 351 ARG 351 1810 1810 ARG ARG A . n 
A 1 352 LYS 352 1811 1811 LYS LYS A . n 
A 1 353 TRP 353 1812 1812 TRP TRP A . n 
A 1 354 PRO 354 1813 1813 PRO PRO A . n 
A 1 355 GLN 355 1814 1814 GLN GLN A . n 
A 1 356 GLY 356 1815 1815 GLY GLY A . n 
A 1 357 ALA 357 1816 1816 ALA ALA A . n 
A 1 358 VAL 358 1817 1817 VAL VAL A . n 
A 1 359 PRO 359 1818 1818 PRO PRO A . n 
A 1 360 GLN 360 1819 1819 GLN GLN A . n 
A 1 361 LEU 361 1820 1820 LEU LEU A . n 
A 1 362 PRO 362 1821 1821 PRO PRO A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 FMT 1   1901 1901 FMT FMT A . 
C 2 FMT 1   1902 1903 FMT FMT A . 
D 2 FMT 1   1903 1904 FMT FMT A . 
E 2 FMT 1   1904 1905 FMT FMT A . 
F 2 FMT 1   1905 1907 FMT FMT A . 
G 2 FMT 1   1906 1911 FMT FMT A . 
H 2 FMT 1   1907 1913 FMT FMT A . 
I 2 FMT 1   1908 1914 FMT FMT A . 
J 2 FMT 1   1909 1915 FMT FMT A . 
K 3 ZN  1   1910 1    ZN  ZN  A . 
L 3 ZN  1   1911 2    ZN  ZN  A . 
M 3 ZN  1   1912 4    ZN  ZN  A . 
N 3 ZN  1   1913 5    ZN  ZN  A . 
O 4 GOL 1   1914 1    GOL GOL A . 
P 5 NA  1   1915 1    NA  NA  A . 
Q 6 HOH 1   2001 438  HOH HOH A . 
Q 6 HOH 2   2002 447  HOH HOH A . 
Q 6 HOH 3   2003 505  HOH HOH A . 
Q 6 HOH 4   2004 461  HOH HOH A . 
Q 6 HOH 5   2005 494  HOH HOH A . 
Q 6 HOH 6   2006 393  HOH HOH A . 
Q 6 HOH 7   2007 434  HOH HOH A . 
Q 6 HOH 8   2008 433  HOH HOH A . 
Q 6 HOH 9   2009 482  HOH HOH A . 
Q 6 HOH 10  2010 408  HOH HOH A . 
Q 6 HOH 11  2011 208  HOH HOH A . 
Q 6 HOH 12  2012 384  HOH HOH A . 
Q 6 HOH 13  2013 243  HOH HOH A . 
Q 6 HOH 14  2014 413  HOH HOH A . 
Q 6 HOH 15  2015 340  HOH HOH A . 
Q 6 HOH 16  2016 214  HOH HOH A . 
Q 6 HOH 17  2017 91   HOH HOH A . 
Q 6 HOH 18  2018 415  HOH HOH A . 
Q 6 HOH 19  2019 281  HOH HOH A . 
Q 6 HOH 20  2020 224  HOH HOH A . 
Q 6 HOH 21  2021 420  HOH HOH A . 
Q 6 HOH 22  2022 177  HOH HOH A . 
Q 6 HOH 23  2023 103  HOH HOH A . 
Q 6 HOH 24  2024 418  HOH HOH A . 
Q 6 HOH 25  2025 190  HOH HOH A . 
Q 6 HOH 26  2026 196  HOH HOH A . 
Q 6 HOH 27  2027 326  HOH HOH A . 
Q 6 HOH 28  2028 48   HOH HOH A . 
Q 6 HOH 29  2029 159  HOH HOH A . 
Q 6 HOH 30  2030 252  HOH HOH A . 
Q 6 HOH 31  2031 76   HOH HOH A . 
Q 6 HOH 32  2032 250  HOH HOH A . 
Q 6 HOH 33  2033 473  HOH HOH A . 
Q 6 HOH 34  2034 410  HOH HOH A . 
Q 6 HOH 35  2035 206  HOH HOH A . 
Q 6 HOH 36  2036 80   HOH HOH A . 
Q 6 HOH 37  2037 230  HOH HOH A . 
Q 6 HOH 38  2038 165  HOH HOH A . 
Q 6 HOH 39  2039 49   HOH HOH A . 
Q 6 HOH 40  2040 492  HOH HOH A . 
Q 6 HOH 41  2041 154  HOH HOH A . 
Q 6 HOH 42  2042 267  HOH HOH A . 
Q 6 HOH 43  2043 260  HOH HOH A . 
Q 6 HOH 44  2044 112  HOH HOH A . 
Q 6 HOH 45  2045 271  HOH HOH A . 
Q 6 HOH 46  2046 204  HOH HOH A . 
Q 6 HOH 47  2047 395  HOH HOH A . 
Q 6 HOH 48  2048 83   HOH HOH A . 
Q 6 HOH 49  2049 257  HOH HOH A . 
Q 6 HOH 50  2050 399  HOH HOH A . 
Q 6 HOH 51  2051 283  HOH HOH A . 
Q 6 HOH 52  2052 247  HOH HOH A . 
Q 6 HOH 53  2053 173  HOH HOH A . 
Q 6 HOH 54  2054 183  HOH HOH A . 
Q 6 HOH 55  2055 162  HOH HOH A . 
Q 6 HOH 56  2056 20   HOH HOH A . 
Q 6 HOH 57  2057 466  HOH HOH A . 
Q 6 HOH 58  2058 33   HOH HOH A . 
Q 6 HOH 59  2059 464  HOH HOH A . 
Q 6 HOH 60  2060 35   HOH HOH A . 
Q 6 HOH 61  2061 348  HOH HOH A . 
Q 6 HOH 62  2062 81   HOH HOH A . 
Q 6 HOH 63  2063 72   HOH HOH A . 
Q 6 HOH 64  2064 246  HOH HOH A . 
Q 6 HOH 65  2065 171  HOH HOH A . 
Q 6 HOH 66  2066 146  HOH HOH A . 
Q 6 HOH 67  2067 84   HOH HOH A . 
Q 6 HOH 68  2068 261  HOH HOH A . 
Q 6 HOH 69  2069 96   HOH HOH A . 
Q 6 HOH 70  2070 104  HOH HOH A . 
Q 6 HOH 71  2071 11   HOH HOH A . 
Q 6 HOH 72  2072 10   HOH HOH A . 
Q 6 HOH 73  2073 151  HOH HOH A . 
Q 6 HOH 74  2074 18   HOH HOH A . 
Q 6 HOH 75  2075 97   HOH HOH A . 
Q 6 HOH 76  2076 44   HOH HOH A . 
Q 6 HOH 77  2077 263  HOH HOH A . 
Q 6 HOH 78  2078 290  HOH HOH A . 
Q 6 HOH 79  2079 41   HOH HOH A . 
Q 6 HOH 80  2080 424  HOH HOH A . 
Q 6 HOH 81  2081 411  HOH HOH A . 
Q 6 HOH 82  2082 407  HOH HOH A . 
Q 6 HOH 83  2083 64   HOH HOH A . 
Q 6 HOH 84  2084 241  HOH HOH A . 
Q 6 HOH 85  2085 256  HOH HOH A . 
Q 6 HOH 86  2086 79   HOH HOH A . 
Q 6 HOH 87  2087 423  HOH HOH A . 
Q 6 HOH 88  2088 166  HOH HOH A . 
Q 6 HOH 89  2089 391  HOH HOH A . 
Q 6 HOH 90  2090 122  HOH HOH A . 
Q 6 HOH 91  2091 201  HOH HOH A . 
Q 6 HOH 92  2092 149  HOH HOH A . 
Q 6 HOH 93  2093 58   HOH HOH A . 
Q 6 HOH 94  2094 210  HOH HOH A . 
Q 6 HOH 95  2095 92   HOH HOH A . 
Q 6 HOH 96  2096 392  HOH HOH A . 
Q 6 HOH 97  2097 42   HOH HOH A . 
Q 6 HOH 98  2098 463  HOH HOH A . 
Q 6 HOH 99  2099 475  HOH HOH A . 
Q 6 HOH 100 2100 426  HOH HOH A . 
Q 6 HOH 101 2101 128  HOH HOH A . 
Q 6 HOH 102 2102 106  HOH HOH A . 
Q 6 HOH 103 2103 121  HOH HOH A . 
Q 6 HOH 104 2104 215  HOH HOH A . 
Q 6 HOH 105 2105 98   HOH HOH A . 
Q 6 HOH 106 2106 220  HOH HOH A . 
Q 6 HOH 107 2107 421  HOH HOH A . 
Q 6 HOH 108 2108 21   HOH HOH A . 
Q 6 HOH 109 2109 69   HOH HOH A . 
Q 6 HOH 110 2110 40   HOH HOH A . 
Q 6 HOH 111 2111 63   HOH HOH A . 
Q 6 HOH 112 2112 182  HOH HOH A . 
Q 6 HOH 113 2113 124  HOH HOH A . 
Q 6 HOH 114 2114 15   HOH HOH A . 
Q 6 HOH 115 2115 125  HOH HOH A . 
Q 6 HOH 116 2116 192  HOH HOH A . 
Q 6 HOH 117 2117 59   HOH HOH A . 
Q 6 HOH 118 2118 140  HOH HOH A . 
Q 6 HOH 119 2119 78   HOH HOH A . 
Q 6 HOH 120 2120 86   HOH HOH A . 
Q 6 HOH 121 2121 115  HOH HOH A . 
Q 6 HOH 122 2122 240  HOH HOH A . 
Q 6 HOH 123 2123 105  HOH HOH A . 
Q 6 HOH 124 2124 70   HOH HOH A . 
Q 6 HOH 125 2125 127  HOH HOH A . 
Q 6 HOH 126 2126 55   HOH HOH A . 
Q 6 HOH 127 2127 52   HOH HOH A . 
Q 6 HOH 128 2128 118  HOH HOH A . 
Q 6 HOH 129 2129 23   HOH HOH A . 
Q 6 HOH 130 2130 47   HOH HOH A . 
Q 6 HOH 131 2131 133  HOH HOH A . 
Q 6 HOH 132 2132 458  HOH HOH A . 
Q 6 HOH 133 2133 264  HOH HOH A . 
Q 6 HOH 134 2134 1    HOH HOH A . 
Q 6 HOH 135 2135 375  HOH HOH A . 
Q 6 HOH 136 2136 269  HOH HOH A . 
Q 6 HOH 137 2137 248  HOH HOH A . 
Q 6 HOH 138 2138 234  HOH HOH A . 
Q 6 HOH 139 2139 180  HOH HOH A . 
Q 6 HOH 140 2140 9    HOH HOH A . 
Q 6 HOH 141 2141 143  HOH HOH A . 
Q 6 HOH 142 2142 419  HOH HOH A . 
Q 6 HOH 143 2143 126  HOH HOH A . 
Q 6 HOH 144 2144 142  HOH HOH A . 
Q 6 HOH 145 2145 46   HOH HOH A . 
Q 6 HOH 146 2146 100  HOH HOH A . 
Q 6 HOH 147 2147 244  HOH HOH A . 
Q 6 HOH 148 2148 178  HOH HOH A . 
Q 6 HOH 149 2149 89   HOH HOH A . 
Q 6 HOH 150 2150 6    HOH HOH A . 
Q 6 HOH 151 2151 54   HOH HOH A . 
Q 6 HOH 152 2152 299  HOH HOH A . 
Q 6 HOH 153 2153 120  HOH HOH A . 
Q 6 HOH 154 2154 499  HOH HOH A . 
Q 6 HOH 155 2155 231  HOH HOH A . 
Q 6 HOH 156 2156 53   HOH HOH A . 
Q 6 HOH 157 2157 61   HOH HOH A . 
Q 6 HOH 158 2158 12   HOH HOH A . 
Q 6 HOH 159 2159 71   HOH HOH A . 
Q 6 HOH 160 2160 39   HOH HOH A . 
Q 6 HOH 161 2161 131  HOH HOH A . 
Q 6 HOH 162 2162 497  HOH HOH A . 
Q 6 HOH 163 2163 134  HOH HOH A . 
Q 6 HOH 164 2164 307  HOH HOH A . 
Q 6 HOH 165 2165 400  HOH HOH A . 
Q 6 HOH 166 2166 158  HOH HOH A . 
Q 6 HOH 167 2167 156  HOH HOH A . 
Q 6 HOH 168 2168 22   HOH HOH A . 
Q 6 HOH 169 2169 181  HOH HOH A . 
Q 6 HOH 170 2170 24   HOH HOH A . 
Q 6 HOH 171 2171 13   HOH HOH A . 
Q 6 HOH 172 2172 82   HOH HOH A . 
Q 6 HOH 173 2173 45   HOH HOH A . 
Q 6 HOH 174 2174 266  HOH HOH A . 
Q 6 HOH 175 2175 99   HOH HOH A . 
Q 6 HOH 176 2176 7    HOH HOH A . 
Q 6 HOH 177 2177 51   HOH HOH A . 
Q 6 HOH 178 2178 101  HOH HOH A . 
Q 6 HOH 179 2179 491  HOH HOH A . 
Q 6 HOH 180 2180 95   HOH HOH A . 
Q 6 HOH 181 2181 2    HOH HOH A . 
Q 6 HOH 182 2182 28   HOH HOH A . 
Q 6 HOH 183 2183 448  HOH HOH A . 
Q 6 HOH 184 2184 74   HOH HOH A . 
Q 6 HOH 185 2185 209  HOH HOH A . 
Q 6 HOH 186 2186 50   HOH HOH A . 
Q 6 HOH 187 2187 57   HOH HOH A . 
Q 6 HOH 188 2188 148  HOH HOH A . 
Q 6 HOH 189 2189 211  HOH HOH A . 
Q 6 HOH 190 2190 123  HOH HOH A . 
Q 6 HOH 191 2191 102  HOH HOH A . 
Q 6 HOH 192 2192 300  HOH HOH A . 
Q 6 HOH 193 2193 31   HOH HOH A . 
Q 6 HOH 194 2194 43   HOH HOH A . 
Q 6 HOH 195 2195 282  HOH HOH A . 
Q 6 HOH 196 2196 450  HOH HOH A . 
Q 6 HOH 197 2197 17   HOH HOH A . 
Q 6 HOH 198 2198 398  HOH HOH A . 
Q 6 HOH 199 2199 229  HOH HOH A . 
Q 6 HOH 200 2200 73   HOH HOH A . 
Q 6 HOH 201 2201 403  HOH HOH A . 
Q 6 HOH 202 2202 16   HOH HOH A . 
Q 6 HOH 203 2203 138  HOH HOH A . 
Q 6 HOH 204 2204 406  HOH HOH A . 
Q 6 HOH 205 2205 108  HOH HOH A . 
Q 6 HOH 206 2206 117  HOH HOH A . 
Q 6 HOH 207 2207 370  HOH HOH A . 
Q 6 HOH 208 2208 449  HOH HOH A . 
Q 6 HOH 209 2209 4    HOH HOH A . 
Q 6 HOH 210 2210 474  HOH HOH A . 
Q 6 HOH 211 2211 75   HOH HOH A . 
Q 6 HOH 212 2212 179  HOH HOH A . 
Q 6 HOH 213 2213 87   HOH HOH A . 
Q 6 HOH 214 2214 145  HOH HOH A . 
Q 6 HOH 215 2215 404  HOH HOH A . 
Q 6 HOH 216 2216 14   HOH HOH A . 
Q 6 HOH 217 2217 193  HOH HOH A . 
Q 6 HOH 218 2218 185  HOH HOH A . 
Q 6 HOH 219 2219 160  HOH HOH A . 
Q 6 HOH 220 2220 233  HOH HOH A . 
Q 6 HOH 221 2221 197  HOH HOH A . 
Q 6 HOH 222 2222 184  HOH HOH A . 
Q 6 HOH 223 2223 163  HOH HOH A . 
Q 6 HOH 224 2224 5    HOH HOH A . 
Q 6 HOH 225 2225 170  HOH HOH A . 
Q 6 HOH 226 2226 116  HOH HOH A . 
Q 6 HOH 227 2227 429  HOH HOH A . 
Q 6 HOH 228 2228 417  HOH HOH A . 
Q 6 HOH 229 2229 200  HOH HOH A . 
Q 6 HOH 230 2230 480  HOH HOH A . 
Q 6 HOH 231 2231 62   HOH HOH A . 
Q 6 HOH 232 2232 277  HOH HOH A . 
Q 6 HOH 233 2233 176  HOH HOH A . 
Q 6 HOH 234 2234 279  HOH HOH A . 
Q 6 HOH 235 2235 221  HOH HOH A . 
Q 6 HOH 236 2236 287  HOH HOH A . 
Q 6 HOH 237 2237 175  HOH HOH A . 
Q 6 HOH 238 2238 236  HOH HOH A . 
Q 6 HOH 239 2239 141  HOH HOH A . 
Q 6 HOH 240 2240 199  HOH HOH A . 
Q 6 HOH 241 2241 195  HOH HOH A . 
Q 6 HOH 242 2242 36   HOH HOH A . 
Q 6 HOH 243 2243 303  HOH HOH A . 
Q 6 HOH 244 2244 275  HOH HOH A . 
Q 6 HOH 245 2245 169  HOH HOH A . 
Q 6 HOH 246 2246 268  HOH HOH A . 
Q 6 HOH 247 2247 194  HOH HOH A . 
Q 6 HOH 248 2248 249  HOH HOH A . 
Q 6 HOH 249 2249 389  HOH HOH A . 
Q 6 HOH 250 2250 38   HOH HOH A . 
Q 6 HOH 251 2251 85   HOH HOH A . 
Q 6 HOH 252 2252 280  HOH HOH A . 
Q 6 HOH 253 2253 226  HOH HOH A . 
Q 6 HOH 254 2254 478  HOH HOH A . 
Q 6 HOH 255 2255 238  HOH HOH A . 
Q 6 HOH 256 2256 60   HOH HOH A . 
Q 6 HOH 257 2257 130  HOH HOH A . 
Q 6 HOH 258 2258 445  HOH HOH A . 
Q 6 HOH 259 2259 68   HOH HOH A . 
Q 6 HOH 260 2260 328  HOH HOH A . 
Q 6 HOH 261 2261 316  HOH HOH A . 
Q 6 HOH 262 2262 113  HOH HOH A . 
Q 6 HOH 263 2263 205  HOH HOH A . 
Q 6 HOH 264 2264 153  HOH HOH A . 
Q 6 HOH 265 2265 119  HOH HOH A . 
Q 6 HOH 266 2266 26   HOH HOH A . 
Q 6 HOH 267 2267 25   HOH HOH A . 
Q 6 HOH 268 2268 30   HOH HOH A . 
Q 6 HOH 269 2269 29   HOH HOH A . 
Q 6 HOH 270 2270 327  HOH HOH A . 
Q 6 HOH 271 2271 207  HOH HOH A . 
Q 6 HOH 272 2272 336  HOH HOH A . 
Q 6 HOH 273 2273 37   HOH HOH A . 
Q 6 HOH 274 2274 56   HOH HOH A . 
Q 6 HOH 275 2275 77   HOH HOH A . 
Q 6 HOH 276 2276 427  HOH HOH A . 
Q 6 HOH 277 2277 111  HOH HOH A . 
Q 6 HOH 278 2278 353  HOH HOH A . 
Q 6 HOH 279 2279 469  HOH HOH A . 
Q 6 HOH 280 2280 251  HOH HOH A . 
Q 6 HOH 281 2281 139  HOH HOH A . 
Q 6 HOH 282 2282 155  HOH HOH A . 
Q 6 HOH 283 2283 422  HOH HOH A . 
Q 6 HOH 284 2284 414  HOH HOH A . 
Q 6 HOH 285 2285 320  HOH HOH A . 
Q 6 HOH 286 2286 90   HOH HOH A . 
Q 6 HOH 287 2287 94   HOH HOH A . 
Q 6 HOH 288 2288 189  HOH HOH A . 
Q 6 HOH 289 2289 129  HOH HOH A . 
Q 6 HOH 290 2290 401  HOH HOH A . 
Q 6 HOH 291 2291 332  HOH HOH A . 
Q 6 HOH 292 2292 289  HOH HOH A . 
Q 6 HOH 293 2293 157  HOH HOH A . 
Q 6 HOH 294 2294 293  HOH HOH A . 
Q 6 HOH 295 2295 409  HOH HOH A . 
Q 6 HOH 296 2296 253  HOH HOH A . 
Q 6 HOH 297 2297 172  HOH HOH A . 
Q 6 HOH 298 2298 137  HOH HOH A . 
Q 6 HOH 299 2299 416  HOH HOH A . 
Q 6 HOH 300 2300 212  HOH HOH A . 
Q 6 HOH 301 2301 34   HOH HOH A . 
Q 6 HOH 302 2302 351  HOH HOH A . 
Q 6 HOH 303 2303 168  HOH HOH A . 
Q 6 HOH 304 2304 88   HOH HOH A . 
Q 6 HOH 305 2305 502  HOH HOH A . 
Q 6 HOH 306 2306 278  HOH HOH A . 
Q 6 HOH 307 2307 276  HOH HOH A . 
Q 6 HOH 308 2308 245  HOH HOH A . 
Q 6 HOH 309 2309 394  HOH HOH A . 
Q 6 HOH 310 2310 476  HOH HOH A . 
Q 6 HOH 311 2311 161  HOH HOH A . 
Q 6 HOH 312 2312 459  HOH HOH A . 
Q 6 HOH 313 2313 412  HOH HOH A . 
Q 6 HOH 314 2314 318  HOH HOH A . 
Q 6 HOH 315 2315 66   HOH HOH A . 
Q 6 HOH 316 2316 239  HOH HOH A . 
Q 6 HOH 317 2317 232  HOH HOH A . 
Q 6 HOH 318 2318 397  HOH HOH A . 
Q 6 HOH 319 2319 437  HOH HOH A . 
Q 6 HOH 320 2320 452  HOH HOH A . 
Q 6 HOH 321 2321 273  HOH HOH A . 
Q 6 HOH 322 2322 405  HOH HOH A . 
Q 6 HOH 323 2323 188  HOH HOH A . 
Q 6 HOH 324 2324 362  HOH HOH A . 
Q 6 HOH 325 2325 296  HOH HOH A . 
Q 6 HOH 326 2326 309  HOH HOH A . 
Q 6 HOH 327 2327 315  HOH HOH A . 
Q 6 HOH 328 2328 135  HOH HOH A . 
Q 6 HOH 329 2329 465  HOH HOH A . 
Q 6 HOH 330 2330 468  HOH HOH A . 
Q 6 HOH 331 2331 150  HOH HOH A . 
Q 6 HOH 332 2332 164  HOH HOH A . 
Q 6 HOH 333 2333 379  HOH HOH A . 
Q 6 HOH 334 2334 498  HOH HOH A . 
Q 6 HOH 335 2335 493  HOH HOH A . 
Q 6 HOH 336 2336 363  HOH HOH A . 
Q 6 HOH 337 2337 323  HOH HOH A . 
Q 6 HOH 338 2338 219  HOH HOH A . 
Q 6 HOH 339 2339 365  HOH HOH A . 
Q 6 HOH 340 2340 371  HOH HOH A . 
Q 6 HOH 341 2341 477  HOH HOH A . 
Q 6 HOH 342 2342 152  HOH HOH A . 
Q 6 HOH 343 2343 191  HOH HOH A . 
Q 6 HOH 344 2344 440  HOH HOH A . 
Q 6 HOH 345 2345 311  HOH HOH A . 
Q 6 HOH 346 2346 305  HOH HOH A . 
Q 6 HOH 347 2347 107  HOH HOH A . 
Q 6 HOH 348 2348 435  HOH HOH A . 
Q 6 HOH 349 2349 114  HOH HOH A . 
Q 6 HOH 350 2350 331  HOH HOH A . 
Q 6 HOH 351 2351 356  HOH HOH A . 
Q 6 HOH 352 2352 284  HOH HOH A . 
Q 6 HOH 353 2353 93   HOH HOH A . 
Q 6 HOH 354 2354 32   HOH HOH A . 
Q 6 HOH 355 2355 144  HOH HOH A . 
Q 6 HOH 356 2356 501  HOH HOH A . 
Q 6 HOH 357 2357 471  HOH HOH A . 
Q 6 HOH 358 2358 270  HOH HOH A . 
Q 6 HOH 359 2359 374  HOH HOH A . 
Q 6 HOH 360 2360 367  HOH HOH A . 
Q 6 HOH 361 2361 372  HOH HOH A . 
Q 6 HOH 362 2362 460  HOH HOH A . 
Q 6 HOH 363 2363 235  HOH HOH A . 
Q 6 HOH 364 2364 324  HOH HOH A . 
Q 6 HOH 365 2365 361  HOH HOH A . 
Q 6 HOH 366 2366 352  HOH HOH A . 
Q 6 HOH 367 2367 237  HOH HOH A . 
Q 6 HOH 368 2368 402  HOH HOH A . 
Q 6 HOH 369 2369 341  HOH HOH A . 
Q 6 HOH 370 2370 385  HOH HOH A . 
Q 6 HOH 371 2371 359  HOH HOH A . 
Q 6 HOH 372 2372 430  HOH HOH A . 
Q 6 HOH 373 2373 481  HOH HOH A . 
Q 6 HOH 374 2374 467  HOH HOH A . 
Q 6 HOH 375 2375 288  HOH HOH A . 
Q 6 HOH 376 2376 350  HOH HOH A . 
Q 6 HOH 377 2377 382  HOH HOH A . 
Q 6 HOH 378 2378 274  HOH HOH A . 
Q 6 HOH 379 2379 484  HOH HOH A . 
Q 6 HOH 380 2380 354  HOH HOH A . 
Q 6 HOH 381 2381 65   HOH HOH A . 
Q 6 HOH 382 2382 490  HOH HOH A . 
Q 6 HOH 383 2383 242  HOH HOH A . 
Q 6 HOH 384 2384 439  HOH HOH A . 
Q 6 HOH 385 2385 304  HOH HOH A . 
Q 6 HOH 386 2386 485  HOH HOH A . 
Q 6 HOH 387 2387 228  HOH HOH A . 
Q 6 HOH 388 2388 441  HOH HOH A . 
Q 6 HOH 389 2389 504  HOH HOH A . 
Q 6 HOH 390 2390 132  HOH HOH A . 
Q 6 HOH 391 2391 446  HOH HOH A . 
Q 6 HOH 392 2392 339  HOH HOH A . 
Q 6 HOH 393 2393 488  HOH HOH A . 
Q 6 HOH 394 2394 167  HOH HOH A . 
Q 6 HOH 395 2395 259  HOH HOH A . 
Q 6 HOH 396 2396 487  HOH HOH A . 
Q 6 HOH 397 2397 174  HOH HOH A . 
Q 6 HOH 398 2398 443  HOH HOH A . 
Q 6 HOH 399 2399 500  HOH HOH A . 
Q 6 HOH 400 2400 298  HOH HOH A . 
Q 6 HOH 401 2401 222  HOH HOH A . 
Q 6 HOH 402 2402 355  HOH HOH A . 
Q 6 HOH 403 2403 147  HOH HOH A . 
Q 6 HOH 404 2404 387  HOH HOH A . 
Q 6 HOH 405 2405 337  HOH HOH A . 
Q 6 HOH 406 2406 217  HOH HOH A . 
Q 6 HOH 407 2407 203  HOH HOH A . 
Q 6 HOH 408 2408 456  HOH HOH A . 
Q 6 HOH 409 2409 344  HOH HOH A . 
Q 6 HOH 410 2410 377  HOH HOH A . 
Q 6 HOH 411 2411 258  HOH HOH A . 
Q 6 HOH 412 2412 321  HOH HOH A . 
Q 6 HOH 413 2413 366  HOH HOH A . 
Q 6 HOH 414 2414 453  HOH HOH A . 
Q 6 HOH 415 2415 292  HOH HOH A . 
Q 6 HOH 416 2416 109  HOH HOH A . 
Q 6 HOH 417 2417 227  HOH HOH A . 
Q 6 HOH 418 2418 432  HOH HOH A . 
Q 6 HOH 419 2419 388  HOH HOH A . 
Q 6 HOH 420 2420 431  HOH HOH A . 
Q 6 HOH 421 2421 286  HOH HOH A . 
Q 6 HOH 422 2422 262  HOH HOH A . 
Q 6 HOH 423 2423 364  HOH HOH A . 
Q 6 HOH 424 2424 470  HOH HOH A . 
Q 6 HOH 425 2425 373  HOH HOH A . 
Q 6 HOH 426 2426 386  HOH HOH A . 
Q 6 HOH 427 2427 27   HOH HOH A . 
Q 6 HOH 428 2428 265  HOH HOH A . 
Q 6 HOH 429 2429 368  HOH HOH A . 
Q 6 HOH 430 2430 376  HOH HOH A . 
Q 6 HOH 431 2431 495  HOH HOH A . 
Q 6 HOH 432 2432 317  HOH HOH A . 
Q 6 HOH 433 2433 369  HOH HOH A . 
Q 6 HOH 434 2434 380  HOH HOH A . 
Q 6 HOH 435 2435 360  HOH HOH A . 
Q 6 HOH 436 2436 381  HOH HOH A . 
Q 6 HOH 437 2437 110  HOH HOH A . 
Q 6 HOH 438 2438 285  HOH HOH A . 
Q 6 HOH 439 2439 136  HOH HOH A . 
Q 6 HOH 440 2440 272  HOH HOH A . 
Q 6 HOH 441 2441 457  HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 1460 ? CG  ? A LYS 1   CG  
2  1 Y 1 A LYS 1460 ? CD  ? A LYS 1   CD  
3  1 Y 1 A LYS 1460 ? CE  ? A LYS 1   CE  
4  1 Y 1 A LYS 1460 ? NZ  ? A LYS 1   NZ  
5  1 Y 1 A ARG 1507 ? CG  ? A ARG 48  CG  
6  1 Y 1 A ARG 1507 ? CD  ? A ARG 48  CD  
7  1 Y 1 A ARG 1507 ? NE  ? A ARG 48  NE  
8  1 Y 1 A ARG 1507 ? CZ  ? A ARG 48  CZ  
9  1 Y 1 A ARG 1507 ? NH1 ? A ARG 48  NH1 
10 1 Y 1 A ARG 1507 ? NH2 ? A ARG 48  NH2 
11 1 Y 1 A GLU 1561 ? CG  ? A GLU 102 CG  
12 1 Y 1 A GLU 1561 ? CD  ? A GLU 102 CD  
13 1 Y 1 A GLU 1561 ? OE1 ? A GLU 102 OE1 
14 1 Y 1 A GLU 1561 ? OE2 ? A GLU 102 OE2 
15 1 Y 1 A THR 1562 ? OG1 ? A THR 103 OG1 
16 1 Y 1 A THR 1562 ? CG2 ? A THR 103 CG2 
17 1 Y 1 A PHE 1563 ? CG  ? A PHE 104 CG  
18 1 Y 1 A PHE 1563 ? CD1 ? A PHE 104 CD1 
19 1 Y 1 A PHE 1563 ? CD2 ? A PHE 104 CD2 
20 1 Y 1 A PHE 1563 ? CE1 ? A PHE 104 CE1 
21 1 Y 1 A PHE 1563 ? CE2 ? A PHE 104 CE2 
22 1 Y 1 A PHE 1563 ? CZ  ? A PHE 104 CZ  
23 1 Y 1 A SER 1564 ? OG  ? A SER 105 OG  
24 1 Y 1 A GLU 1565 ? CG  ? A GLU 106 CG  
25 1 Y 1 A GLU 1565 ? CD  ? A GLU 106 CD  
26 1 Y 1 A GLU 1565 ? OE1 ? A GLU 106 OE1 
27 1 Y 1 A GLU 1565 ? OE2 ? A GLU 106 OE2 
28 1 Y 1 A ARG 1567 ? CG  ? A ARG 108 CG  
29 1 Y 1 A ARG 1567 ? CD  ? A ARG 108 CD  
30 1 Y 1 A ARG 1567 ? NE  ? A ARG 108 NE  
31 1 Y 1 A ARG 1567 ? CZ  ? A ARG 108 CZ  
32 1 Y 1 A ARG 1567 ? NH1 ? A ARG 108 NH1 
33 1 Y 1 A ARG 1567 ? NH2 ? A ARG 108 NH2 
34 1 Y 0 A GLU 1663 ? CA  B A GLU 204 CA  
35 1 Y 0 A GLU 1663 ? CB  B A GLU 204 CB  
36 1 Y 0 A GLU 1663 ? CG  B A GLU 204 CG  
37 1 Y 0 A GLU 1663 ? CD  B A GLU 204 CD  
38 1 Y 0 A GLU 1663 ? OE1 B A GLU 204 OE1 
39 1 Y 0 A GLU 1663 ? OE2 B A GLU 204 OE2 
40 1 Y 1 A ARG 1667 ? CG  ? A ARG 208 CG  
41 1 Y 1 A ARG 1667 ? CD  ? A ARG 208 CD  
42 1 Y 1 A ARG 1667 ? NE  ? A ARG 208 NE  
43 1 Y 1 A ARG 1667 ? CZ  ? A ARG 208 CZ  
44 1 Y 1 A ARG 1667 ? NH1 ? A ARG 208 NH1 
45 1 Y 1 A ARG 1667 ? NH2 ? A ARG 208 NH2 
46 1 Y 1 A ARG 1699 ? CG  ? A ARG 240 CG  
47 1 Y 1 A ARG 1699 ? CD  ? A ARG 240 CD  
48 1 Y 1 A ARG 1699 ? NE  ? A ARG 240 NE  
49 1 Y 1 A ARG 1699 ? CZ  ? A ARG 240 CZ  
50 1 Y 1 A ARG 1699 ? NH1 ? A ARG 240 NH1 
51 1 Y 1 A ARG 1699 ? NH2 ? A ARG 240 NH2 
52 1 Y 1 A GLU 1746 ? CG  ? A GLU 287 CG  
53 1 Y 1 A GLU 1746 ? CD  ? A GLU 287 CD  
54 1 Y 1 A GLU 1746 ? OE1 ? A GLU 287 OE1 
55 1 Y 1 A GLU 1746 ? OE2 ? A GLU 287 OE2 
56 1 Y 1 A ARG 1785 ? CG  ? A ARG 326 CG  
57 1 Y 1 A ARG 1785 ? CD  ? A ARG 326 CD  
58 1 Y 1 A ARG 1785 ? NE  ? A ARG 326 NE  
59 1 Y 1 A ARG 1785 ? CZ  ? A ARG 326 CZ  
60 1 Y 1 A ARG 1785 ? NH1 ? A ARG 326 NH1 
61 1 Y 1 A ARG 1785 ? NH2 ? A ARG 326 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? EDNA     ? ? ? .           1 
? 'data processing' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .           2 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? Aimless  ? ? ? .           3 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? 'CCP4 v8.0' 4 
? refinement        ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 'CCP4 v8.0' 5 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 6 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FS3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     82.099 
_cell.length_a_esd                 ? 
_cell.length_b                     158.499 
_cell.length_b_esd                 ? 
_cell.length_c                     61.842 
_cell.length_c_esd                 ? 
_cell.volume                       804725.791 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FS3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FS3 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.54 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.50 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES pH 7, 2.5 M sodium formate,' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 X 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-04-11 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97926 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALBA BEAMLINE XALOC' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97926 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   XALOC 
_diffrn_source.pdbx_synchrotron_site       ALBA 
# 
_reflns.B_iso_Wilson_estimate                          11.66 
_reflns.entry_id                                       9FS3 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.18 
_reflns.d_resolution_low                               48.75 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     130558 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.28 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.95 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.95 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.18 
_reflns_shell.d_res_low                                     1.22 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.85 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             12435 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.433 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               16.48 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FS3 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.18 
_refine.ls_d_res_low                             48.75 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     130231 
_refine.ls_number_reflns_R_free                  6582 
_refine.ls_number_reflns_R_work                  123649 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.27 
_refine.ls_percent_reflns_R_free                 5.05 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1565 
_refine.ls_R_factor_R_free                       0.1785 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1554 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 19.3887 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1631 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.18 
_refine_hist.d_res_low                        48.75 
_refine_hist.number_atoms_solvent             441 
_refine_hist.number_atoms_total               3216 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2737 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         38 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0090 ? 3000 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.1466 ? 4117 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0858 ? 469  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0114 ? 544  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 7.3760 ? 434  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.18 1.19  . . 213 3909 94.30 . . . . 0.3457 . . . . . . . . . . . 0.3463 
'X-RAY DIFFRACTION' 1.19 1.21  . . 214 3964 95.00 . . . . 0.3421 . . . . . . . . . . . 0.3568 
'X-RAY DIFFRACTION' 1.21 1.22  . . 245 3925 95.47 . . . . 0.3418 . . . . . . . . . . . 0.3830 
'X-RAY DIFFRACTION' 1.22 1.24  . . 197 3988 95.70 . . . . 0.3243 . . . . . . . . . . . 0.3510 
'X-RAY DIFFRACTION' 1.24 1.25  . . 226 3999 97.06 . . . . 0.2947 . . . . . . . . . . . 0.3098 
'X-RAY DIFFRACTION' 1.25 1.27  . . 220 4025 96.50 . . . . 0.2843 . . . . . . . . . . . 0.3173 
'X-RAY DIFFRACTION' 1.27 1.29  . . 206 4004 96.45 . . . . 0.2638 . . . . . . . . . . . 0.2897 
'X-RAY DIFFRACTION' 1.29 1.31  . . 209 4109 98.18 . . . . 0.2547 . . . . . . . . . . . 0.2819 
'X-RAY DIFFRACTION' 1.31 1.33  . . 207 4079 98.01 . . . . 0.2438 . . . . . . . . . . . 0.2527 
'X-RAY DIFFRACTION' 1.33 1.35  . . 233 4084 98.00 . . . . 0.2334 . . . . . . . . . . . 0.2626 
'X-RAY DIFFRACTION' 1.35 1.37  . . 244 4091 98.28 . . . . 0.2153 . . . . . . . . . . . 0.2400 
'X-RAY DIFFRACTION' 1.37 1.40  . . 202 4110 99.45 . . . . 0.1983 . . . . . . . . . . . 0.2177 
'X-RAY DIFFRACTION' 1.40 1.42  . . 235 4129 99.23 . . . . 0.1909 . . . . . . . . . . . 0.2197 
'X-RAY DIFFRACTION' 1.42 1.45  . . 234 4127 99.32 . . . . 0.1851 . . . . . . . . . . . 0.2274 
'X-RAY DIFFRACTION' 1.45 1.49  . . 262 4110 99.39 . . . . 0.1808 . . . . . . . . . . . 0.2149 
'X-RAY DIFFRACTION' 1.49 1.52  . . 216 4161 99.57 . . . . 0.1684 . . . . . . . . . . . 0.1989 
'X-RAY DIFFRACTION' 1.52 1.56  . . 209 4194 99.66 . . . . 0.1417 . . . . . . . . . . . 0.1598 
'X-RAY DIFFRACTION' 1.56 1.60  . . 211 4159 99.75 . . . . 0.1329 . . . . . . . . . . . 0.1604 
'X-RAY DIFFRACTION' 1.60 1.65  . . 219 4183 99.71 . . . . 0.1288 . . . . . . . . . . . 0.1536 
'X-RAY DIFFRACTION' 1.65 1.70  . . 210 4192 99.84 . . . . 0.1266 . . . . . . . . . . . 0.1534 
'X-RAY DIFFRACTION' 1.70 1.76  . . 225 4176 99.62 . . . . 0.1276 . . . . . . . . . . . 0.1397 
'X-RAY DIFFRACTION' 1.76 1.83  . . 194 4189 98.98 . . . . 0.1248 . . . . . . . . . . . 0.1564 
'X-RAY DIFFRACTION' 1.83 1.91  . . 220 4185 99.95 . . . . 0.1283 . . . . . . . . . . . 0.1551 
'X-RAY DIFFRACTION' 1.91 2.02  . . 223 4221 99.93 . . . . 0.1276 . . . . . . . . . . . 0.1520 
'X-RAY DIFFRACTION' 2.02 2.14  . . 243 4187 99.91 . . . . 0.1194 . . . . . . . . . . . 0.1480 
'X-RAY DIFFRACTION' 2.14 2.31  . . 205 4250 99.84 . . . . 0.1201 . . . . . . . . . . . 0.1437 
'X-RAY DIFFRACTION' 2.31 2.54  . . 208 4228 99.48 . . . . 0.1282 . . . . . . . . . . . 0.1378 
'X-RAY DIFFRACTION' 2.54 2.91  . . 214 4214 98.80 . . . . 0.1382 . . . . . . . . . . . 0.1513 
'X-RAY DIFFRACTION' 2.91 3.66  . . 230 4158 96.87 . . . . 0.1335 . . . . . . . . . . . 0.1629 
'X-RAY DIFFRACTION' 3.66 48.75 . . 208 4299 95.83 . . . . 0.1399 . . . . . . . . . . . 0.1548 
# 
_struct.entry_id                     9FS3 
_struct.title                        'Mutant S1538A of the dihydroorotase domain of human CAD protein in apo form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FS3 
_struct_keywords.text            
'Nucleotide metabolism, de novo pyrimidine synthesis, CAD disease, multienzymatic protein, zinc, carboxylated lysine, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 2 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 4 ? 
P N N 5 ? 
Q N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PYR1_HUMAN 
_struct_ref.pdbx_db_accession          P27708 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;KLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASS
ENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKE
EILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSR
PPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKV
KGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQLP
;
_struct_ref.pdbx_align_begin           1460 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9FS3 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 362 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P27708 
_struct_ref_seq.db_align_beg                  1460 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1821 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1460 
_struct_ref_seq.pdbx_auth_seq_align_end       1821 
# 
_struct_ref_seq_dif.align_id                     1 
_struct_ref_seq_dif.pdbx_pdb_id_code             9FS3 
_struct_ref_seq_dif.mon_id                       ALA 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      79 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   P27708 
_struct_ref_seq_dif.db_mon_id                    SER 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          1538 
_struct_ref_seq_dif.details                      'engineered mutation' 
_struct_ref_seq_dif.pdbx_auth_seq_num            1538 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5790  ? 
1 MORE         -314  ? 
1 'SSA (A^2)'  26170 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 4_555 x,-y,-z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 25  ? GLY A 36  ? ASP A 1484 GLY A 1495 1 ? 12 
HELX_P HELX_P2  AA2 ASP A 53  ? ALA A 68  ? ASP A 1512 ALA A 1527 1 ? 16 
HELX_P HELX_P3  AA3 VAL A 89  ? ALA A 93  ? VAL A 1548 ALA A 1552 5 ? 5  
HELX_P HELX_P4  AA4 SER A 111 ? TRP A 122 ? SER A 1570 TRP A 1581 1 ? 12 
HELX_P HELX_P5  AA5 GLN A 134 ? THR A 147 ? GLN A 1593 THR A 1606 1 ? 14 
HELX_P HELX_P6  AA6 ARG A 158 ? ARG A 171 ? ARG A 1617 ARG A 1630 1 ? 14 
HELX_P HELX_P7  AA7 PRO A 181 ? LEU A 186 ? PRO A 1640 LEU A 1645 1 ? 6  
HELX_P HELX_P8  AA8 SER A 187 ? ASP A 189 ? SER A 1646 ASP A 1648 5 ? 3  
HELX_P HELX_P9  AA9 ASP A 190 ? GLY A 199 ? ASP A 1649 GLY A 1658 1 ? 10 
HELX_P HELX_P10 AB1 SER A 207 ? ASN A 217 ? SER A 1666 ASN A 1676 1 ? 11 
HELX_P HELX_P11 AB2 MET A 218 ? ILE A 221 ? MET A 1677 ILE A 1680 5 ? 4  
HELX_P HELX_P12 AB3 THR A 232 ? GLY A 238 ? THR A 1691 GLY A 1697 1 ? 7  
HELX_P HELX_P13 AB4 GLY A 247 ? GLU A 261 ? GLY A 1706 GLU A 1720 1 ? 15 
HELX_P HELX_P14 AB5 SER A 265 ? HIS A 274 ? SER A 1724 HIS A 1733 1 ? 10 
HELX_P HELX_P15 AB6 HIS A 274 ? HIS A 282 ? HIS A 1733 HIS A 1741 1 ? 9  
HELX_P HELX_P16 AB7 ASP A 349 ? ALA A 357 ? ASP A 1808 ALA A 1816 5 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? A LEU 96  C   ? ? ? 1_555 A KCX 97 N  ? ? A LEU 1555 A KCX 1556 1_555 ? ? ? ? ? ? ? 1.331 ? ? 
covale2  covale both ? A KCX 97  C   ? ? ? 1_555 A LEU 98 N  A ? A KCX 1556 A LEU 1557 1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale3  covale both ? A KCX 97  C   ? ? ? 1_555 A LEU 98 N  B ? A KCX 1556 A LEU 1557 1_555 ? ? ? ? ? ? ? 1.336 ? ? 
metalc1  metalc ?    ? A HIS 12  NE2 ? ? ? 1_555 L ZN  .  ZN ? ? A HIS 1471 A ZN  1911 1_555 ? ? ? ? ? ? ? 2.067 ? ? 
metalc2  metalc ?    ? A HIS 12  ND1 ? ? ? 1_555 M ZN  .  ZN ? ? A HIS 1471 A ZN  1912 1_555 ? ? ? ? ? ? ? 2.056 ? ? 
metalc3  metalc ?    ? A HIS 14  NE2 ? ? ? 1_555 L ZN  .  ZN ? ? A HIS 1473 A ZN  1911 1_555 ? ? ? ? ? ? ? 2.070 ? ? 
metalc4  metalc ?    ? A GLU 65  O   ? ? ? 1_555 P NA  .  NA ? ? A GLU 1524 A NA  1915 1_555 ? ? ? ? ? ? ? 2.521 ? ? 
metalc5  metalc ?    ? A KCX 97  OQ1 ? ? ? 1_555 K ZN  .  ZN ? ? A KCX 1556 A ZN  1910 1_555 ? ? ? ? ? ? ? 1.924 ? ? 
metalc6  metalc ?    ? A KCX 97  OQ2 ? ? ? 1_555 L ZN  .  ZN ? ? A KCX 1556 A ZN  1911 1_555 ? ? ? ? ? ? ? 2.158 ? ? 
metalc7  metalc ?    ? A HIS 131 ND1 ? ? ? 1_555 K ZN  .  ZN ? ? A HIS 1590 A ZN  1910 1_555 ? ? ? ? ? ? ? 2.117 ? ? 
metalc8  metalc ?    ? A CYS 154 SG  ? ? ? 1_555 M ZN  .  ZN ? ? A CYS 1613 A ZN  1912 1_555 ? ? ? ? ? ? ? 2.335 ? ? 
metalc9  metalc ?    ? A HIS 155 NE2 ? ? ? 1_555 K ZN  .  ZN ? ? A HIS 1614 A ZN  1910 1_555 ? ? ? ? ? ? ? 2.081 ? ? 
metalc10 metalc ?    ? A GLU 178 OE2 ? ? ? 1_555 M ZN  .  ZN ? ? A GLU 1637 A ZN  1912 1_555 ? ? ? ? ? ? ? 2.126 ? ? 
metalc11 metalc ?    ? A ASP 227 OD1 ? ? ? 1_555 L ZN  .  ZN ? ? A ASP 1686 A ZN  1911 1_555 ? ? ? ? ? ? ? 2.192 ? ? 
metalc12 metalc ?    ? A HIS 275 NE2 ? ? ? 1_555 N ZN  .  ZN ? ? A HIS 1734 A ZN  1913 1_555 ? ? ? ? ? ? ? 2.120 ? ? 
metalc13 metalc ?    ? A HIS 282 ND1 ? ? ? 1_555 N ZN  .  ZN ? ? A HIS 1741 A ZN  1913 3_554 ? ? ? ? ? ? ? 2.137 ? ? 
metalc14 metalc ?    ? A GLY 345 O   ? ? ? 1_555 P NA  .  NA ? ? A GLY 1804 A NA  1915 1_555 ? ? ? ? ? ? ? 2.431 ? ? 
metalc15 metalc ?    ? A GLY 347 O   ? ? ? 1_555 P NA  .  NA ? ? A GLY 1806 A NA  1915 1_555 ? ? ? ? ? ? ? 2.360 ? ? 
metalc16 metalc ?    ? G FMT .   O1  ? ? ? 1_555 N ZN  .  ZN ? ? A FMT 1906 A ZN  1913 1_555 ? ? ? ? ? ? ? 1.991 ? ? 
metalc17 metalc ?    ? K ZN  .   ZN  ? ? ? 1_555 Q HOH .  O  ? ? A ZN  1910 A HOH 2134 1_555 ? ? ? ? ? ? ? 1.983 ? ? 
metalc18 metalc ?    ? L ZN  .   ZN  ? ? ? 1_555 Q HOH .  O  ? ? A ZN  1911 A HOH 2134 1_555 ? ? ? ? ? ? ? 1.954 ? ? 
metalc19 metalc ?    ? M ZN  .   ZN  ? ? ? 1_555 Q HOH .  O  ? ? A ZN  1912 A HOH 2181 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
metalc20 metalc ?    ? N ZN  .   ZN  ? ? ? 1_555 Q HOH .  O  ? ? A ZN  1913 A HOH 2319 1_555 ? ? ? ? ? ? ? 2.205 ? ? 
metalc21 metalc ?    ? P NA  .   NA  ? ? ? 1_555 Q HOH .  O  ? ? A NA  1915 A HOH 2268 1_555 ? ? ? ? ? ? ? 2.205 ? ? 
metalc22 metalc ?    ? P NA  .   NA  ? ? ? 1_555 Q HOH .  O  ? ? A NA  1915 A HOH 2275 1_555 ? ? ? ? ? ? ? 2.690 ? ? 
metalc23 metalc ?    ? P NA  .   NA  ? ? ? 1_555 Q HOH .  O  ? ? A NA  1915 A HOH 2328 1_555 ? ? ? ? ? ? ? 2.378 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 NE2 ? A HIS 14  ? A HIS 1473 ? 1_555 114.9 ? 
2  NE2 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 OQ2 ? A KCX 97  ? A KCX 1556 ? 1_555 90.6  ? 
3  NE2 ? A HIS 14  ? A HIS 1473 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 OQ2 ? A KCX 97  ? A KCX 1556 ? 1_555 91.8  ? 
4  NE2 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 OD1 ? A ASP 227 ? A ASP 1686 ? 1_555 84.2  ? 
5  NE2 ? A HIS 14  ? A HIS 1473 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 OD1 ? A ASP 227 ? A ASP 1686 ? 1_555 90.0  ? 
6  OQ2 ? A KCX 97  ? A KCX 1556 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 OD1 ? A ASP 227 ? A ASP 1686 ? 1_555 174.7 ? 
7  NE2 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 118.1 ? 
8  NE2 ? A HIS 14  ? A HIS 1473 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 126.9 ? 
9  OQ2 ? A KCX 97  ? A KCX 1556 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 91.3  ? 
10 OD1 ? A ASP 227 ? A ASP 1686 ? 1_555 ZN ? L ZN . ? A ZN 1911 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 91.6  ? 
11 ND1 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 SG  ? A CYS 154 ? A CYS 1613 ? 1_555 112.9 ? 
12 ND1 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 OE2 ? A GLU 178 ? A GLU 1637 ? 1_555 88.8  ? 
13 SG  ? A CYS 154 ? A CYS 1613 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 OE2 ? A GLU 178 ? A GLU 1637 ? 1_555 115.3 ? 
14 ND1 ? A HIS 12  ? A HIS 1471 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 O   ? Q HOH .   ? A HOH 2181 ? 1_555 119.2 ? 
15 SG  ? A CYS 154 ? A CYS 1613 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 O   ? Q HOH .   ? A HOH 2181 ? 1_555 111.3 ? 
16 OE2 ? A GLU 178 ? A GLU 1637 ? 1_555 ZN ? M ZN . ? A ZN 1912 ? 1_555 O   ? Q HOH .   ? A HOH 2181 ? 1_555 107.6 ? 
17 O   ? A GLU 65  ? A GLU 1524 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? A GLY 345 ? A GLY 1804 ? 1_555 89.1  ? 
18 O   ? A GLU 65  ? A GLU 1524 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? A GLY 347 ? A GLY 1806 ? 1_555 106.5 ? 
19 O   ? A GLY 345 ? A GLY 1804 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? A GLY 347 ? A GLY 1806 ? 1_555 93.6  ? 
20 O   ? A GLU 65  ? A GLU 1524 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2268 ? 1_555 76.9  ? 
21 O   ? A GLY 345 ? A GLY 1804 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2268 ? 1_555 80.8  ? 
22 O   ? A GLY 347 ? A GLY 1806 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2268 ? 1_555 173.5 ? 
23 O   ? A GLU 65  ? A GLU 1524 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2275 ? 1_555 151.7 ? 
24 O   ? A GLY 345 ? A GLY 1804 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2275 ? 1_555 70.8  ? 
25 O   ? A GLY 347 ? A GLY 1806 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2275 ? 1_555 94.8  ? 
26 O   ? Q HOH .   ? A HOH 2268 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2275 ? 1_555 80.3  ? 
27 O   ? A GLU 65  ? A GLU 1524 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2328 ? 1_555 111.6 ? 
28 O   ? A GLY 345 ? A GLY 1804 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2328 ? 1_555 153.9 ? 
29 O   ? A GLY 347 ? A GLY 1806 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2328 ? 1_555 95.3  ? 
30 O   ? Q HOH .   ? A HOH 2268 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2328 ? 1_555 88.5  ? 
31 O   ? Q HOH .   ? A HOH 2275 ? 1_555 NA ? P NA . ? A NA 1915 ? 1_555 O   ? Q HOH .   ? A HOH 2328 ? 1_555 84.0  ? 
32 OQ1 ? A KCX 97  ? A KCX 1556 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 ND1 ? A HIS 131 ? A HIS 1590 ? 1_555 105.7 ? 
33 OQ1 ? A KCX 97  ? A KCX 1556 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 NE2 ? A HIS 155 ? A HIS 1614 ? 1_555 112.8 ? 
34 ND1 ? A HIS 131 ? A HIS 1590 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 NE2 ? A HIS 155 ? A HIS 1614 ? 1_555 94.5  ? 
35 OQ1 ? A KCX 97  ? A KCX 1556 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 104.8 ? 
36 ND1 ? A HIS 131 ? A HIS 1590 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 131.0 ? 
37 NE2 ? A HIS 155 ? A HIS 1614 ? 1_555 ZN ? K ZN . ? A ZN 1910 ? 1_555 O   ? Q HOH .   ? A HOH 2134 ? 1_555 107.6 ? 
38 NE2 ? A HIS 275 ? A HIS 1734 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 ND1 ? A HIS 282 ? A HIS 1741 ? 1_555 26.9  ? 
39 NE2 ? A HIS 275 ? A HIS 1734 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 O1  ? G FMT .   ? A FMT 1906 ? 1_555 104.6 ? 
40 ND1 ? A HIS 282 ? A HIS 1741 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 O1  ? G FMT .   ? A FMT 1906 ? 1_555 78.1  ? 
41 NE2 ? A HIS 275 ? A HIS 1734 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 O   ? Q HOH .   ? A HOH 2319 ? 1_555 103.5 ? 
42 ND1 ? A HIS 282 ? A HIS 1741 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 O   ? Q HOH .   ? A HOH 2319 ? 1_555 110.5 ? 
43 O1  ? G FMT .   ? A FMT 1906 ? 1_555 ZN ? N ZN . ? A ZN 1913 ? 1_555 O   ? Q HOH .   ? A HOH 2319 ? 1_555 112.8 ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      KCX 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       97 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       KCX 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        1556 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                LYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        KCX 
_pdbx_modification_feature.type                               Carboxylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 17  A . ? GLU 1476 A PRO 18  A ? PRO 1477 A 1 5.75  
2 ARG 48  A . ? ARG 1507 A PRO 49  A ? PRO 1508 A 1 1.39  
3 ARG 202 A . ? ARG 1661 A PRO 203 A ? PRO 1662 A 1 -8.90 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 3   ? PRO A 6   ? VAL A 1462 PRO A 1465 
AA1 2 TYR A 290 ? THR A 300 ? TYR A 1749 THR A 1759 
AA1 3 LYS A 319 ? LEU A 329 ? LYS A 1778 LEU A 1788 
AA1 4 GLU A 332 ? ILE A 336 ? GLU A 1791 ILE A 1795 
AA1 5 GLN A 339 ? VAL A 340 ? GLN A 1798 VAL A 1799 
AA2 1 LEU A 8   ? VAL A 13  ? LEU A 1467 VAL A 1472 
AA2 2 ILE A 38  ? ALA A 43  ? ILE A 1497 ALA A 1502 
AA2 3 ASP A 71  ? LEU A 74  ? ASP A 1530 LEU A 1533 
AA3 1 LEU A 76  ? GLY A 77  ? LEU A 1535 GLY A 1536 
AA3 2 LEU A 96  ? TYR A 99  ? LEU A 1555 TYR A 1558 
AA3 3 ILE A 128 ? HIS A 131 ? ILE A 1587 HIS A 1590 
AA3 4 VAL A 151 ? ILE A 153 ? VAL A 1610 ILE A 1612 
AA3 5 VAL A 175 ? VAL A 179 ? VAL A 1634 VAL A 1638 
AA3 6 CYS A 223 ? PHE A 224 ? CYS A 1682 PHE A 1683 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 5   ? N LEU A 1464 O VAL A 291 ? O VAL A 1750 
AA1 2 3 N GLU A 292 ? N GLU A 1751 O ARG A 326 ? O ARG A 1785 
AA1 3 4 N VAL A 327 ? N VAL A 1786 O ALA A 334 ? O ALA A 1793 
AA1 4 5 N ILE A 336 ? N ILE A 1795 O GLN A 339 ? O GLN A 1798 
AA2 1 2 N ASP A 10  ? N ASP A 1469 O MET A 40  ? O MET A 1499 
AA2 2 3 N ALA A 43  ? N ALA A 1502 O ALA A 73  ? O ALA A 1532 
AA3 1 2 N LEU A 76  ? N LEU A 1535 O KCX A 97  ? O KCX A 1556 
AA3 2 3 N LEU A 96  ? N LEU A 1555 O VAL A 129 ? O VAL A 1588 
AA3 3 4 N ALA A 130 ? N ALA A 1589 O HIS A 152 ? O HIS A 1611 
AA3 4 5 N ILE A 153 ? N ILE A 1612 O THR A 176 ? O THR A 1635 
AA3 5 6 N VAL A 179 ? N VAL A 1638 O CYS A 223 ? O CYS A 1682 
# 
_pdbx_entry_details.entry_id                   9FS3 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 1471 ? ? -150.86 89.82   
2  1 GLU A 1483 ? ? 175.68  153.62  
3  1 ASN A 1505 ? ? -87.30  46.88   
4  1 ASN A 1560 ? ? -108.91 -137.62 
5  1 GLU A 1561 ? ? -29.49  -101.82 
6  1 THR A 1562 ? ? 86.86   157.06  
7  1 GLN A 1593 ? ? 53.60   -127.82 
8  1 HIS A 1614 ? ? 18.76   78.15   
9  1 HIS A 1733 ? ? -147.71 -67.46  
10 1 ASP A 1796 ? ? 38.13   50.92   
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    KCX 
_pdbx_struct_mod_residue.label_seq_id     97 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     KCX 
_pdbx_struct_mod_residue.auth_seq_id      1556 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   LYS 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A FMT 1908 ? I FMT . 
2 1 A HOH 2363 ? Q HOH . 
3 1 A HOH 2391 ? Q HOH . 
4 1 A HOH 2432 ? Q HOH . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 2435 ? 5.86 . 
2 1 O ? A HOH 2436 ? 5.93 . 
3 1 O ? A HOH 2437 ? 6.02 . 
4 1 O ? A HOH 2438 ? 6.35 . 
5 1 O ? A HOH 2439 ? 6.44 . 
6 1 O ? A HOH 2440 ? 7.00 . 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FMT C    C  N N 88  
FMT O1   O  N N 89  
FMT O2   O  N N 90  
FMT H    H  N N 91  
FMT HO2  H  N N 92  
GLN N    N  N N 93  
GLN CA   C  N S 94  
GLN C    C  N N 95  
GLN O    O  N N 96  
GLN CB   C  N N 97  
GLN CG   C  N N 98  
GLN CD   C  N N 99  
GLN OE1  O  N N 100 
GLN NE2  N  N N 101 
GLN OXT  O  N N 102 
GLN H    H  N N 103 
GLN H2   H  N N 104 
GLN HA   H  N N 105 
GLN HB2  H  N N 106 
GLN HB3  H  N N 107 
GLN HG2  H  N N 108 
GLN HG3  H  N N 109 
GLN HE21 H  N N 110 
GLN HE22 H  N N 111 
GLN HXT  H  N N 112 
GLU N    N  N N 113 
GLU CA   C  N S 114 
GLU C    C  N N 115 
GLU O    O  N N 116 
GLU CB   C  N N 117 
GLU CG   C  N N 118 
GLU CD   C  N N 119 
GLU OE1  O  N N 120 
GLU OE2  O  N N 121 
GLU OXT  O  N N 122 
GLU H    H  N N 123 
GLU H2   H  N N 124 
GLU HA   H  N N 125 
GLU HB2  H  N N 126 
GLU HB3  H  N N 127 
GLU HG2  H  N N 128 
GLU HG3  H  N N 129 
GLU HE2  H  N N 130 
GLU HXT  H  N N 131 
GLY N    N  N N 132 
GLY CA   C  N N 133 
GLY C    C  N N 134 
GLY O    O  N N 135 
GLY OXT  O  N N 136 
GLY H    H  N N 137 
GLY H2   H  N N 138 
GLY HA2  H  N N 139 
GLY HA3  H  N N 140 
GLY HXT  H  N N 141 
GOL C1   C  N N 142 
GOL O1   O  N N 143 
GOL C2   C  N N 144 
GOL O2   O  N N 145 
GOL C3   C  N N 146 
GOL O3   O  N N 147 
GOL H11  H  N N 148 
GOL H12  H  N N 149 
GOL HO1  H  N N 150 
GOL H2   H  N N 151 
GOL HO2  H  N N 152 
GOL H31  H  N N 153 
GOL H32  H  N N 154 
GOL HO3  H  N N 155 
HIS N    N  N N 156 
HIS CA   C  N S 157 
HIS C    C  N N 158 
HIS O    O  N N 159 
HIS CB   C  N N 160 
HIS CG   C  Y N 161 
HIS ND1  N  Y N 162 
HIS CD2  C  Y N 163 
HIS CE1  C  Y N 164 
HIS NE2  N  Y N 165 
HIS OXT  O  N N 166 
HIS H    H  N N 167 
HIS H2   H  N N 168 
HIS HA   H  N N 169 
HIS HB2  H  N N 170 
HIS HB3  H  N N 171 
HIS HD1  H  N N 172 
HIS HD2  H  N N 173 
HIS HE1  H  N N 174 
HIS HE2  H  N N 175 
HIS HXT  H  N N 176 
HOH O    O  N N 177 
HOH H1   H  N N 178 
HOH H2   H  N N 179 
ILE N    N  N N 180 
ILE CA   C  N S 181 
ILE C    C  N N 182 
ILE O    O  N N 183 
ILE CB   C  N S 184 
ILE CG1  C  N N 185 
ILE CG2  C  N N 186 
ILE CD1  C  N N 187 
ILE OXT  O  N N 188 
ILE H    H  N N 189 
ILE H2   H  N N 190 
ILE HA   H  N N 191 
ILE HB   H  N N 192 
ILE HG12 H  N N 193 
ILE HG13 H  N N 194 
ILE HG21 H  N N 195 
ILE HG22 H  N N 196 
ILE HG23 H  N N 197 
ILE HD11 H  N N 198 
ILE HD12 H  N N 199 
ILE HD13 H  N N 200 
ILE HXT  H  N N 201 
KCX N    N  N N 202 
KCX CA   C  N S 203 
KCX CB   C  N N 204 
KCX CG   C  N N 205 
KCX CD   C  N N 206 
KCX CE   C  N N 207 
KCX NZ   N  N N 208 
KCX C    C  N N 209 
KCX O    O  N N 210 
KCX CX   C  N N 211 
KCX OXT  O  N N 212 
KCX OQ1  O  N N 213 
KCX OQ2  O  N N 214 
KCX H    H  N N 215 
KCX H2   H  N N 216 
KCX HA   H  N N 217 
KCX HB2  H  N N 218 
KCX HB3  H  N N 219 
KCX HG2  H  N N 220 
KCX HG3  H  N N 221 
KCX HD2  H  N N 222 
KCX HD3  H  N N 223 
KCX HE2  H  N N 224 
KCX HE3  H  N N 225 
KCX HZ   H  N N 226 
KCX HXT  H  N N 227 
KCX HQ2  H  N N 228 
LEU N    N  N N 229 
LEU CA   C  N S 230 
LEU C    C  N N 231 
LEU O    O  N N 232 
LEU CB   C  N N 233 
LEU CG   C  N N 234 
LEU CD1  C  N N 235 
LEU CD2  C  N N 236 
LEU OXT  O  N N 237 
LEU H    H  N N 238 
LEU H2   H  N N 239 
LEU HA   H  N N 240 
LEU HB2  H  N N 241 
LEU HB3  H  N N 242 
LEU HG   H  N N 243 
LEU HD11 H  N N 244 
LEU HD12 H  N N 245 
LEU HD13 H  N N 246 
LEU HD21 H  N N 247 
LEU HD22 H  N N 248 
LEU HD23 H  N N 249 
LEU HXT  H  N N 250 
LYS N    N  N N 251 
LYS CA   C  N S 252 
LYS C    C  N N 253 
LYS O    O  N N 254 
LYS CB   C  N N 255 
LYS CG   C  N N 256 
LYS CD   C  N N 257 
LYS CE   C  N N 258 
LYS NZ   N  N N 259 
LYS OXT  O  N N 260 
LYS H    H  N N 261 
LYS H2   H  N N 262 
LYS HA   H  N N 263 
LYS HB2  H  N N 264 
LYS HB3  H  N N 265 
LYS HG2  H  N N 266 
LYS HG3  H  N N 267 
LYS HD2  H  N N 268 
LYS HD3  H  N N 269 
LYS HE2  H  N N 270 
LYS HE3  H  N N 271 
LYS HZ1  H  N N 272 
LYS HZ2  H  N N 273 
LYS HZ3  H  N N 274 
LYS HXT  H  N N 275 
MET N    N  N N 276 
MET CA   C  N S 277 
MET C    C  N N 278 
MET O    O  N N 279 
MET CB   C  N N 280 
MET CG   C  N N 281 
MET SD   S  N N 282 
MET CE   C  N N 283 
MET OXT  O  N N 284 
MET H    H  N N 285 
MET H2   H  N N 286 
MET HA   H  N N 287 
MET HB2  H  N N 288 
MET HB3  H  N N 289 
MET HG2  H  N N 290 
MET HG3  H  N N 291 
MET HE1  H  N N 292 
MET HE2  H  N N 293 
MET HE3  H  N N 294 
MET HXT  H  N N 295 
NA  NA   NA N N 296 
PHE N    N  N N 297 
PHE CA   C  N S 298 
PHE C    C  N N 299 
PHE O    O  N N 300 
PHE CB   C  N N 301 
PHE CG   C  Y N 302 
PHE CD1  C  Y N 303 
PHE CD2  C  Y N 304 
PHE CE1  C  Y N 305 
PHE CE2  C  Y N 306 
PHE CZ   C  Y N 307 
PHE OXT  O  N N 308 
PHE H    H  N N 309 
PHE H2   H  N N 310 
PHE HA   H  N N 311 
PHE HB2  H  N N 312 
PHE HB3  H  N N 313 
PHE HD1  H  N N 314 
PHE HD2  H  N N 315 
PHE HE1  H  N N 316 
PHE HE2  H  N N 317 
PHE HZ   H  N N 318 
PHE HXT  H  N N 319 
PRO N    N  N N 320 
PRO CA   C  N S 321 
PRO C    C  N N 322 
PRO O    O  N N 323 
PRO CB   C  N N 324 
PRO CG   C  N N 325 
PRO CD   C  N N 326 
PRO OXT  O  N N 327 
PRO H    H  N N 328 
PRO HA   H  N N 329 
PRO HB2  H  N N 330 
PRO HB3  H  N N 331 
PRO HG2  H  N N 332 
PRO HG3  H  N N 333 
PRO HD2  H  N N 334 
PRO HD3  H  N N 335 
PRO HXT  H  N N 336 
SER N    N  N N 337 
SER CA   C  N S 338 
SER C    C  N N 339 
SER O    O  N N 340 
SER CB   C  N N 341 
SER OG   O  N N 342 
SER OXT  O  N N 343 
SER H    H  N N 344 
SER H2   H  N N 345 
SER HA   H  N N 346 
SER HB2  H  N N 347 
SER HB3  H  N N 348 
SER HG   H  N N 349 
SER HXT  H  N N 350 
THR N    N  N N 351 
THR CA   C  N S 352 
THR C    C  N N 353 
THR O    O  N N 354 
THR CB   C  N R 355 
THR OG1  O  N N 356 
THR CG2  C  N N 357 
THR OXT  O  N N 358 
THR H    H  N N 359 
THR H2   H  N N 360 
THR HA   H  N N 361 
THR HB   H  N N 362 
THR HG1  H  N N 363 
THR HG21 H  N N 364 
THR HG22 H  N N 365 
THR HG23 H  N N 366 
THR HXT  H  N N 367 
TRP N    N  N N 368 
TRP CA   C  N S 369 
TRP C    C  N N 370 
TRP O    O  N N 371 
TRP CB   C  N N 372 
TRP CG   C  Y N 373 
TRP CD1  C  Y N 374 
TRP CD2  C  Y N 375 
TRP NE1  N  Y N 376 
TRP CE2  C  Y N 377 
TRP CE3  C  Y N 378 
TRP CZ2  C  Y N 379 
TRP CZ3  C  Y N 380 
TRP CH2  C  Y N 381 
TRP OXT  O  N N 382 
TRP H    H  N N 383 
TRP H2   H  N N 384 
TRP HA   H  N N 385 
TRP HB2  H  N N 386 
TRP HB3  H  N N 387 
TRP HD1  H  N N 388 
TRP HE1  H  N N 389 
TRP HE3  H  N N 390 
TRP HZ2  H  N N 391 
TRP HZ3  H  N N 392 
TRP HH2  H  N N 393 
TRP HXT  H  N N 394 
TYR N    N  N N 395 
TYR CA   C  N S 396 
TYR C    C  N N 397 
TYR O    O  N N 398 
TYR CB   C  N N 399 
TYR CG   C  Y N 400 
TYR CD1  C  Y N 401 
TYR CD2  C  Y N 402 
TYR CE1  C  Y N 403 
TYR CE2  C  Y N 404 
TYR CZ   C  Y N 405 
TYR OH   O  N N 406 
TYR OXT  O  N N 407 
TYR H    H  N N 408 
TYR H2   H  N N 409 
TYR HA   H  N N 410 
TYR HB2  H  N N 411 
TYR HB3  H  N N 412 
TYR HD1  H  N N 413 
TYR HD2  H  N N 414 
TYR HE1  H  N N 415 
TYR HE2  H  N N 416 
TYR HH   H  N N 417 
TYR HXT  H  N N 418 
VAL N    N  N N 419 
VAL CA   C  N S 420 
VAL C    C  N N 421 
VAL O    O  N N 422 
VAL CB   C  N N 423 
VAL CG1  C  N N 424 
VAL CG2  C  N N 425 
VAL OXT  O  N N 426 
VAL H    H  N N 427 
VAL H2   H  N N 428 
VAL HA   H  N N 429 
VAL HB   H  N N 430 
VAL HG11 H  N N 431 
VAL HG12 H  N N 432 
VAL HG13 H  N N 433 
VAL HG21 H  N N 434 
VAL HG22 H  N N 435 
VAL HG23 H  N N 436 
VAL HXT  H  N N 437 
ZN  ZN   ZN N N 438 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
FMT C   O1   doub N N 83  
FMT C   O2   sing N N 84  
FMT C   H    sing N N 85  
FMT O2  HO2  sing N N 86  
GLN N   CA   sing N N 87  
GLN N   H    sing N N 88  
GLN N   H2   sing N N 89  
GLN CA  C    sing N N 90  
GLN CA  CB   sing N N 91  
GLN CA  HA   sing N N 92  
GLN C   O    doub N N 93  
GLN C   OXT  sing N N 94  
GLN CB  CG   sing N N 95  
GLN CB  HB2  sing N N 96  
GLN CB  HB3  sing N N 97  
GLN CG  CD   sing N N 98  
GLN CG  HG2  sing N N 99  
GLN CG  HG3  sing N N 100 
GLN CD  OE1  doub N N 101 
GLN CD  NE2  sing N N 102 
GLN NE2 HE21 sing N N 103 
GLN NE2 HE22 sing N N 104 
GLN OXT HXT  sing N N 105 
GLU N   CA   sing N N 106 
GLU N   H    sing N N 107 
GLU N   H2   sing N N 108 
GLU CA  C    sing N N 109 
GLU CA  CB   sing N N 110 
GLU CA  HA   sing N N 111 
GLU C   O    doub N N 112 
GLU C   OXT  sing N N 113 
GLU CB  CG   sing N N 114 
GLU CB  HB2  sing N N 115 
GLU CB  HB3  sing N N 116 
GLU CG  CD   sing N N 117 
GLU CG  HG2  sing N N 118 
GLU CG  HG3  sing N N 119 
GLU CD  OE1  doub N N 120 
GLU CD  OE2  sing N N 121 
GLU OE2 HE2  sing N N 122 
GLU OXT HXT  sing N N 123 
GLY N   CA   sing N N 124 
GLY N   H    sing N N 125 
GLY N   H2   sing N N 126 
GLY CA  C    sing N N 127 
GLY CA  HA2  sing N N 128 
GLY CA  HA3  sing N N 129 
GLY C   O    doub N N 130 
GLY C   OXT  sing N N 131 
GLY OXT HXT  sing N N 132 
GOL C1  O1   sing N N 133 
GOL C1  C2   sing N N 134 
GOL C1  H11  sing N N 135 
GOL C1  H12  sing N N 136 
GOL O1  HO1  sing N N 137 
GOL C2  O2   sing N N 138 
GOL C2  C3   sing N N 139 
GOL C2  H2   sing N N 140 
GOL O2  HO2  sing N N 141 
GOL C3  O3   sing N N 142 
GOL C3  H31  sing N N 143 
GOL C3  H32  sing N N 144 
GOL O3  HO3  sing N N 145 
HIS N   CA   sing N N 146 
HIS N   H    sing N N 147 
HIS N   H2   sing N N 148 
HIS CA  C    sing N N 149 
HIS CA  CB   sing N N 150 
HIS CA  HA   sing N N 151 
HIS C   O    doub N N 152 
HIS C   OXT  sing N N 153 
HIS CB  CG   sing N N 154 
HIS CB  HB2  sing N N 155 
HIS CB  HB3  sing N N 156 
HIS CG  ND1  sing Y N 157 
HIS CG  CD2  doub Y N 158 
HIS ND1 CE1  doub Y N 159 
HIS ND1 HD1  sing N N 160 
HIS CD2 NE2  sing Y N 161 
HIS CD2 HD2  sing N N 162 
HIS CE1 NE2  sing Y N 163 
HIS CE1 HE1  sing N N 164 
HIS NE2 HE2  sing N N 165 
HIS OXT HXT  sing N N 166 
HOH O   H1   sing N N 167 
HOH O   H2   sing N N 168 
ILE N   CA   sing N N 169 
ILE N   H    sing N N 170 
ILE N   H2   sing N N 171 
ILE CA  C    sing N N 172 
ILE CA  CB   sing N N 173 
ILE CA  HA   sing N N 174 
ILE C   O    doub N N 175 
ILE C   OXT  sing N N 176 
ILE CB  CG1  sing N N 177 
ILE CB  CG2  sing N N 178 
ILE CB  HB   sing N N 179 
ILE CG1 CD1  sing N N 180 
ILE CG1 HG12 sing N N 181 
ILE CG1 HG13 sing N N 182 
ILE CG2 HG21 sing N N 183 
ILE CG2 HG22 sing N N 184 
ILE CG2 HG23 sing N N 185 
ILE CD1 HD11 sing N N 186 
ILE CD1 HD12 sing N N 187 
ILE CD1 HD13 sing N N 188 
ILE OXT HXT  sing N N 189 
KCX N   CA   sing N N 190 
KCX N   H    sing N N 191 
KCX N   H2   sing N N 192 
KCX CA  CB   sing N N 193 
KCX CA  C    sing N N 194 
KCX CA  HA   sing N N 195 
KCX CB  CG   sing N N 196 
KCX CB  HB2  sing N N 197 
KCX CB  HB3  sing N N 198 
KCX CG  CD   sing N N 199 
KCX CG  HG2  sing N N 200 
KCX CG  HG3  sing N N 201 
KCX CD  CE   sing N N 202 
KCX CD  HD2  sing N N 203 
KCX CD  HD3  sing N N 204 
KCX CE  NZ   sing N N 205 
KCX CE  HE2  sing N N 206 
KCX CE  HE3  sing N N 207 
KCX NZ  CX   sing N N 208 
KCX NZ  HZ   sing N N 209 
KCX C   O    doub N N 210 
KCX C   OXT  sing N N 211 
KCX CX  OQ1  doub N N 212 
KCX CX  OQ2  sing N N 213 
KCX OXT HXT  sing N N 214 
KCX OQ2 HQ2  sing N N 215 
LEU N   CA   sing N N 216 
LEU N   H    sing N N 217 
LEU N   H2   sing N N 218 
LEU CA  C    sing N N 219 
LEU CA  CB   sing N N 220 
LEU CA  HA   sing N N 221 
LEU C   O    doub N N 222 
LEU C   OXT  sing N N 223 
LEU CB  CG   sing N N 224 
LEU CB  HB2  sing N N 225 
LEU CB  HB3  sing N N 226 
LEU CG  CD1  sing N N 227 
LEU CG  CD2  sing N N 228 
LEU CG  HG   sing N N 229 
LEU CD1 HD11 sing N N 230 
LEU CD1 HD12 sing N N 231 
LEU CD1 HD13 sing N N 232 
LEU CD2 HD21 sing N N 233 
LEU CD2 HD22 sing N N 234 
LEU CD2 HD23 sing N N 235 
LEU OXT HXT  sing N N 236 
LYS N   CA   sing N N 237 
LYS N   H    sing N N 238 
LYS N   H2   sing N N 239 
LYS CA  C    sing N N 240 
LYS CA  CB   sing N N 241 
LYS CA  HA   sing N N 242 
LYS C   O    doub N N 243 
LYS C   OXT  sing N N 244 
LYS CB  CG   sing N N 245 
LYS CB  HB2  sing N N 246 
LYS CB  HB3  sing N N 247 
LYS CG  CD   sing N N 248 
LYS CG  HG2  sing N N 249 
LYS CG  HG3  sing N N 250 
LYS CD  CE   sing N N 251 
LYS CD  HD2  sing N N 252 
LYS CD  HD3  sing N N 253 
LYS CE  NZ   sing N N 254 
LYS CE  HE2  sing N N 255 
LYS CE  HE3  sing N N 256 
LYS NZ  HZ1  sing N N 257 
LYS NZ  HZ2  sing N N 258 
LYS NZ  HZ3  sing N N 259 
LYS OXT HXT  sing N N 260 
MET N   CA   sing N N 261 
MET N   H    sing N N 262 
MET N   H2   sing N N 263 
MET CA  C    sing N N 264 
MET CA  CB   sing N N 265 
MET CA  HA   sing N N 266 
MET C   O    doub N N 267 
MET C   OXT  sing N N 268 
MET CB  CG   sing N N 269 
MET CB  HB2  sing N N 270 
MET CB  HB3  sing N N 271 
MET CG  SD   sing N N 272 
MET CG  HG2  sing N N 273 
MET CG  HG3  sing N N 274 
MET SD  CE   sing N N 275 
MET CE  HE1  sing N N 276 
MET CE  HE2  sing N N 277 
MET CE  HE3  sing N N 278 
MET OXT HXT  sing N N 279 
PHE N   CA   sing N N 280 
PHE N   H    sing N N 281 
PHE N   H2   sing N N 282 
PHE CA  C    sing N N 283 
PHE CA  CB   sing N N 284 
PHE CA  HA   sing N N 285 
PHE C   O    doub N N 286 
PHE C   OXT  sing N N 287 
PHE CB  CG   sing N N 288 
PHE CB  HB2  sing N N 289 
PHE CB  HB3  sing N N 290 
PHE CG  CD1  doub Y N 291 
PHE CG  CD2  sing Y N 292 
PHE CD1 CE1  sing Y N 293 
PHE CD1 HD1  sing N N 294 
PHE CD2 CE2  doub Y N 295 
PHE CD2 HD2  sing N N 296 
PHE CE1 CZ   doub Y N 297 
PHE CE1 HE1  sing N N 298 
PHE CE2 CZ   sing Y N 299 
PHE CE2 HE2  sing N N 300 
PHE CZ  HZ   sing N N 301 
PHE OXT HXT  sing N N 302 
PRO N   CA   sing N N 303 
PRO N   CD   sing N N 304 
PRO N   H    sing N N 305 
PRO CA  C    sing N N 306 
PRO CA  CB   sing N N 307 
PRO CA  HA   sing N N 308 
PRO C   O    doub N N 309 
PRO C   OXT  sing N N 310 
PRO CB  CG   sing N N 311 
PRO CB  HB2  sing N N 312 
PRO CB  HB3  sing N N 313 
PRO CG  CD   sing N N 314 
PRO CG  HG2  sing N N 315 
PRO CG  HG3  sing N N 316 
PRO CD  HD2  sing N N 317 
PRO CD  HD3  sing N N 318 
PRO OXT HXT  sing N N 319 
SER N   CA   sing N N 320 
SER N   H    sing N N 321 
SER N   H2   sing N N 322 
SER CA  C    sing N N 323 
SER CA  CB   sing N N 324 
SER CA  HA   sing N N 325 
SER C   O    doub N N 326 
SER C   OXT  sing N N 327 
SER CB  OG   sing N N 328 
SER CB  HB2  sing N N 329 
SER CB  HB3  sing N N 330 
SER OG  HG   sing N N 331 
SER OXT HXT  sing N N 332 
THR N   CA   sing N N 333 
THR N   H    sing N N 334 
THR N   H2   sing N N 335 
THR CA  C    sing N N 336 
THR CA  CB   sing N N 337 
THR CA  HA   sing N N 338 
THR C   O    doub N N 339 
THR C   OXT  sing N N 340 
THR CB  OG1  sing N N 341 
THR CB  CG2  sing N N 342 
THR CB  HB   sing N N 343 
THR OG1 HG1  sing N N 344 
THR CG2 HG21 sing N N 345 
THR CG2 HG22 sing N N 346 
THR CG2 HG23 sing N N 347 
THR OXT HXT  sing N N 348 
TRP N   CA   sing N N 349 
TRP N   H    sing N N 350 
TRP N   H2   sing N N 351 
TRP CA  C    sing N N 352 
TRP CA  CB   sing N N 353 
TRP CA  HA   sing N N 354 
TRP C   O    doub N N 355 
TRP C   OXT  sing N N 356 
TRP CB  CG   sing N N 357 
TRP CB  HB2  sing N N 358 
TRP CB  HB3  sing N N 359 
TRP CG  CD1  doub Y N 360 
TRP CG  CD2  sing Y N 361 
TRP CD1 NE1  sing Y N 362 
TRP CD1 HD1  sing N N 363 
TRP CD2 CE2  doub Y N 364 
TRP CD2 CE3  sing Y N 365 
TRP NE1 CE2  sing Y N 366 
TRP NE1 HE1  sing N N 367 
TRP CE2 CZ2  sing Y N 368 
TRP CE3 CZ3  doub Y N 369 
TRP CE3 HE3  sing N N 370 
TRP CZ2 CH2  doub Y N 371 
TRP CZ2 HZ2  sing N N 372 
TRP CZ3 CH2  sing Y N 373 
TRP CZ3 HZ3  sing N N 374 
TRP CH2 HH2  sing N N 375 
TRP OXT HXT  sing N N 376 
TYR N   CA   sing N N 377 
TYR N   H    sing N N 378 
TYR N   H2   sing N N 379 
TYR CA  C    sing N N 380 
TYR CA  CB   sing N N 381 
TYR CA  HA   sing N N 382 
TYR C   O    doub N N 383 
TYR C   OXT  sing N N 384 
TYR CB  CG   sing N N 385 
TYR CB  HB2  sing N N 386 
TYR CB  HB3  sing N N 387 
TYR CG  CD1  doub Y N 388 
TYR CG  CD2  sing Y N 389 
TYR CD1 CE1  sing Y N 390 
TYR CD1 HD1  sing N N 391 
TYR CD2 CE2  doub Y N 392 
TYR CD2 HD2  sing N N 393 
TYR CE1 CZ   doub Y N 394 
TYR CE1 HE1  sing N N 395 
TYR CE2 CZ   sing Y N 396 
TYR CE2 HE2  sing N N 397 
TYR CZ  OH   sing N N 398 
TYR OH  HH   sing N N 399 
TYR OXT HXT  sing N N 400 
VAL N   CA   sing N N 401 
VAL N   H    sing N N 402 
VAL N   H2   sing N N 403 
VAL CA  C    sing N N 404 
VAL CA  CB   sing N N 405 
VAL CA  HA   sing N N 406 
VAL C   O    doub N N 407 
VAL C   OXT  sing N N 408 
VAL CB  CG1  sing N N 409 
VAL CB  CG2  sing N N 410 
VAL CB  HB   sing N N 411 
VAL CG1 HG11 sing N N 412 
VAL CG1 HG12 sing N N 413 
VAL CG1 HG13 sing N N 414 
VAL CG2 HG21 sing N N 415 
VAL CG2 HG22 sing N N 416 
VAL CG2 HG23 sing N N 417 
VAL OXT HXT  sing N N 418 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministerio de Ciencia e Innovacion (MCIN)' Spain PID2021-128468NB-I00     1 
'Other private'                             ?     'Fundacion Ramon Areces' 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4C6C 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9FS3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012180 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006309 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.016170 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ?       ? 25.62398 1.50364  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ?       ? 24.73122 6.32584  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ?       ? 19.97189 1.75589  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 6.63511  3.01293 1.30238 ? 5.54423  0.54580  90.85902 ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ?       ? 15.80542 1.70748  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ?       ? 1.23737  29.19336 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ?       ? 2.14387  29.76375 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . LYS A 1 1   ? -12.63463 -31.63182 -38.58022 1.000 33.15663 ? 1460 LYS A N    1 
ATOM   2    C  CA   . LYS A 1 1   ? -11.39433 -31.11985 -38.00708 1.000 32.80132 ? 1460 LYS A CA   1 
ATOM   3    C  C    . LYS A 1 1   ? -11.62196 -30.61851 -36.57473 1.000 31.50380 ? 1460 LYS A C    1 
ATOM   4    O  O    . LYS A 1 1   ? -12.05339 -29.48948 -36.35971 1.000 32.23809 ? 1460 LYS A O    1 
ATOM   5    C  CB   . LYS A 1 1   ? -10.83578 -29.98786 -38.87441 1.000 33.42245 ? 1460 LYS A CB   1 
ATOM   6    H  HA   . LYS A 1 1   ? -10.73740 -31.83296 -37.97837 1.000 39.36438 ? 1460 LYS A HA   1 
ATOM   7    N  N    . LEU A 1 2   ? -11.33162 -31.45982 -35.58864 1.000 28.72188 ? 1461 LEU A N    1 
ATOM   8    C  CA   . LEU A 1 2   ? -11.56585 -31.10137 -34.19910 1.000 26.17158 ? 1461 LEU A CA   1 
ATOM   9    C  C    . LEU A 1 2   ? -10.30494 -30.47110 -33.61743 1.000 23.90815 ? 1461 LEU A C    1 
ATOM   10   O  O    . LEU A 1 2   ? -9.18349  -30.78327 -34.02633 1.000 25.11092 ? 1461 LEU A O    1 
ATOM   11   C  CB   . LEU A 1 2   ? -11.94493 -32.35425 -33.40979 1.000 26.50320 ? 1461 LEU A CB   1 
ATOM   12   C  CG   . LEU A 1 2   ? -13.23464 -33.06205 -33.83935 1.000 27.00326 ? 1461 LEU A CG   1 
ATOM   13   C  CD1  . LEU A 1 2   ? -13.63507 -34.09931 -32.79057 1.000 27.99548 ? 1461 LEU A CD1  1 
ATOM   14   C  CD2  . LEU A 1 2   ? -14.38769 -32.09323 -34.06719 1.000 26.79797 ? 1461 LEU A CD2  1 
ATOM   15   H  H    . LEU A 1 2   ? -10.99783 -32.24442 -35.70085 1.000 34.46906 ? 1461 LEU A H    1 
ATOM   16   H  HA   . LEU A 1 2   ? -12.28921 -30.45969 -34.12235 1.000 31.40869 ? 1461 LEU A HA   1 
ATOM   17   H  HB2  . LEU A 1 2   ? -11.22316 -32.99619 -33.49850 1.000 31.80663 ? 1461 LEU A HB2  1 
ATOM   18   H  HB3  . LEU A 1 2   ? -12.05289 -32.10295 -32.47915 1.000 31.80663 ? 1461 LEU A HB3  1 
ATOM   19   H  HG   . LEU A 1 2   ? -13.06002 -33.50038 -34.68686 1.000 32.40671 ? 1461 LEU A HG   1 
ATOM   20   H  HD11 . LEU A 1 2   ? -14.45056 -34.53954 -33.07707 1.000 33.59737 ? 1461 LEU A HD11 1 
ATOM   21   H  HD12 . LEU A 1 2   ? -12.92145 -34.75026 -32.70167 1.000 33.59737 ? 1461 LEU A HD12 1 
ATOM   22   H  HD13 . LEU A 1 2   ? -13.78141 -33.65107 -31.94289 1.000 33.59737 ? 1461 LEU A HD13 1 
ATOM   23   H  HD21 . LEU A 1 2   ? -15.20626 -32.59940 -34.18817 1.000 32.16036 ? 1461 LEU A HD21 1 
ATOM   24   H  HD22 . LEU A 1 2   ? -14.46921 -31.51211 -33.29482 1.000 32.16036 ? 1461 LEU A HD22 1 
ATOM   25   H  HD23 . LEU A 1 2   ? -14.20480 -31.56557 -34.86030 1.000 32.16036 ? 1461 LEU A HD23 1 
ATOM   26   N  N    . VAL A 1 3   ? -10.49617 -29.56043 -32.67934 1.000 20.55775 ? 1462 VAL A N    1 
ATOM   27   C  CA   . VAL A 1 3   ? -9.39311  -28.95297 -31.95373 1.000 18.88913 ? 1462 VAL A CA   1 
ATOM   28   C  C    . VAL A 1 3   ? -9.33330  -29.56678 -30.57189 1.000 16.98100 ? 1462 VAL A C    1 
ATOM   29   O  O    . VAL A 1 3   ? -10.35206 -29.64409 -29.86840 1.000 16.51779 ? 1462 VAL A O    1 
ATOM   30   C  CB   . VAL A 1 3   ? -9.56412  -27.43137 -31.86687 1.000 20.51827 ? 1462 VAL A CB   1 
ATOM   31   C  CG1  . VAL A 1 3   ? -8.36992  -26.80093 -31.18137 1.000 21.61840 ? 1462 VAL A CG1  1 
ATOM   32   C  CG2  . VAL A 1 3   ? -9.73818  -26.86761 -33.24815 1.000 21.27625 ? 1462 VAL A CG2  1 
ATOM   33   H  H    . VAL A 1 3   ? -11.27025 -29.27201 -32.44014 1.000 24.67210 ? 1462 VAL A H    1 
ATOM   34   H  HA   . VAL A 1 3   ? -8.56023  -29.14491 -32.41239 1.000 22.66975 ? 1462 VAL A HA   1 
ATOM   35   H  HB   . VAL A 1 3   ? -10.35209 -27.22327 -31.34085 1.000 24.62472 ? 1462 VAL A HB   1 
ATOM   36   H  HG11 . VAL A 1 3   ? -8.43147  -25.83638 -31.26354 1.000 25.94488 ? 1462 VAL A HG11 1 
ATOM   37   H  HG12 . VAL A 1 3   ? -8.37334  -27.05402 -30.24497 1.000 25.94488 ? 1462 VAL A HG12 1 
ATOM   38   H  HG13 . VAL A 1 3   ? -7.55787  -27.11800 -31.60675 1.000 25.94488 ? 1462 VAL A HG13 1 
ATOM   39   H  HG21 . VAL A 1 3   ? -9.78228  -25.90029 -33.19119 1.000 25.53430 ? 1462 VAL A HG21 1 
ATOM   40   H  HG22 . VAL A 1 3   ? -8.98212  -27.13264 -33.79499 1.000 25.53430 ? 1462 VAL A HG22 1 
ATOM   41   H  HG23 . VAL A 1 3   ? -10.55992 -27.21432 -33.62951 1.000 25.53430 ? 1462 VAL A HG23 1 
ATOM   42   N  N    . ARG A 1 4   ? -8.14474  -29.98937 -30.17877 1.000 16.10722 ? 1463 ARG A N    1 
ATOM   43   C  CA   . ARG A 1 4   ? -7.90614  -30.54929 -28.85899 1.000 16.15459 ? 1463 ARG A CA   1 
ATOM   44   C  C    . ARG A 1 4   ? -7.50600  -29.44390 -27.89864 1.000 15.40976 ? 1463 ARG A C    1 
ATOM   45   O  O    . ARG A 1 4   ? -6.49588  -28.75511 -28.10560 1.000 17.82320 ? 1463 ARG A O    1 
ATOM   46   C  CB   . ARG A 1 4   ? -6.81437  -31.61439 -28.93064 1.000 17.71267 ? 1463 ARG A CB   1 
ATOM   47   C  CG   . ARG A 1 4   ? -6.52502  -32.31245 -27.60325 1.000 19.38392 ? 1463 ARG A CG   1 
ATOM   48   C  CD   . ARG A 1 4   ? -5.29249  -33.21776 -27.70982 1.000 20.59722 ? 1463 ARG A CD   1 
ATOM   49   N  NE   . ARG A 1 4   ? -4.75127  -33.64792 -26.42488 1.000 20.82094 ? 1463 ARG A NE   1 
ATOM   50   C  CZ   . ARG A 1 4   ? -4.46254  -34.90061 -26.11599 1.000 21.87369 ? 1463 ARG A CZ   1 
ATOM   51   N  NH1  . ARG A 1 4   ? -4.70483  -35.89378 -26.95806 1.000 23.64496 ? 1463 ARG A NH1  1 
ATOM   52   N  NH2  . ARG A 1 4   ? -3.88379  -35.16046 -24.94555 1.000 21.19204 ? 1463 ARG A NH2  1 
ATOM   53   H  H    . ARG A 1 4   ? -7.44012  -29.96218 -30.67109 1.000 19.33146 ? 1463 ARG A H    1 
ATOM   54   H  HA   . ARG A 1 4   ? -8.72239  -30.95577 -28.52821 1.000 19.38830 ? 1463 ARG A HA   1 
ATOM   55   H  HB2  . ARG A 1 4   ? -7.08706  -32.29442 -29.56632 1.000 21.25800 ? 1463 ARG A HB2  1 
ATOM   56   H  HB3  . ARG A 1 4   ? -5.99163  -31.19441 -29.22663 1.000 21.25800 ? 1463 ARG A HB3  1 
ATOM   57   H  HG2  . ARG A 1 4   ? -6.35715  -31.64623 -26.91850 1.000 23.26350 ? 1463 ARG A HG2  1 
ATOM   58   H  HG3  . ARG A 1 4   ? -7.28616  -32.85973 -27.35416 1.000 23.26350 ? 1463 ARG A HG3  1 
ATOM   59   H  HD2  . ARG A 1 4   ? -5.53453  -34.01436 -28.20757 1.000 24.71947 ? 1463 ARG A HD2  1 
ATOM   60   H  HD3  . ARG A 1 4   ? -4.59220  -32.73513 -28.17624 1.000 24.71947 ? 1463 ARG A HD3  1 
ATOM   61   H  HE   . ARG A 1 4   ? -4.61045  -33.04540 -25.82761 1.000 24.98792 ? 1463 ARG A HE   1 
ATOM   62   H  HH11 . ARG A 1 4   ? -5.05756  -35.73069 -27.72525 1.000 28.37675 ? 1463 ARG A HH11 1 
ATOM   63   H  HH12 . ARG A 1 4   ? -4.50942  -36.70176 -26.73765 1.000 28.37675 ? 1463 ARG A HH12 1 
ATOM   64   H  HH21 . ARG A 1 4   ? -3.70318  -34.51800 -24.40312 1.000 25.43324 ? 1463 ARG A HH21 1 
ATOM   65   H  HH22 . ARG A 1 4   ? -3.69053  -35.97077 -24.73191 1.000 25.43324 ? 1463 ARG A HH22 1 
ATOM   66   N  N    . LEU A 1 5   ? -8.30148  -29.27056 -26.87365 1.000 13.70956 ? 1464 LEU A N    1 
ATOM   67   C  CA   . LEU A 1 5   ? -8.02929  -28.38029 -25.77787 1.000 12.91736 ? 1464 LEU A CA   1 
ATOM   68   C  C    . LEU A 1 5   ? -7.67303  -29.16674 -24.53520 1.000 12.29623 ? 1464 LEU A C    1 
ATOM   69   O  O    . LEU A 1 5   ? -8.05883  -30.33098 -24.39465 1.000 12.28834 ? 1464 LEU A O    1 
ATOM   70   C  CB   . LEU A 1 5   ? -9.29000  -27.58040 -25.44724 1.000 13.20160 ? 1464 LEU A CB   1 
ATOM   71   C  CG   . LEU A 1 5   ? -9.98837  -26.90674 -26.61876 1.000 14.54913 ? 1464 LEU A CG   1 
ATOM   72   C  CD1  . LEU A 1 5   ? -11.22538 -26.16762 -26.07894 1.000 15.31764 ? 1464 LEU A CD1  1 
ATOM   73   C  CD2  . LEU A 1 5   ? -9.07323  -25.93959 -27.34957 1.000 15.13868 ? 1464 LEU A CD2  1 
ATOM   74   H  H    . LEU A 1 5   ? -9.05085  -29.68316 -26.78535 1.000 16.45427 ? 1464 LEU A H    1 
ATOM   75   H  HA   . LEU A 1 5   ? -7.30026  -27.78628 -26.01571 1.000 15.50363 ? 1464 LEU A HA   1 
ATOM   76   H  HB2  . LEU A 1 5   ? -9.93151  -28.18387 -25.04080 1.000 15.84472 ? 1464 LEU A HB2  1 
ATOM   77   H  HB3  . LEU A 1 5   ? -9.04743  -26.88205 -24.81925 1.000 15.84472 ? 1464 LEU A HB3  1 
ATOM   78   H  HG   . LEU A 1 5   ? -10.25135 -27.57793 -27.26781 1.000 17.46176 ? 1464 LEU A HG   1 
ATOM   79   H  HD11 . LEU A 1 5   ? -11.68706 -25.74260 -26.81862 1.000 18.38397 ? 1464 LEU A HD11 1 
ATOM   80   H  HD12 . LEU A 1 5   ? -11.81215 -26.80780 -25.64678 1.000 18.38397 ? 1464 LEU A HD12 1 
ATOM   81   H  HD13 . LEU A 1 5   ? -10.93853 -25.49739 -25.43909 1.000 18.38397 ? 1464 LEU A HD13 1 
ATOM   82   H  HD21 . LEU A 1 5   ? -9.57690  -25.49645 -28.05017 1.000 18.16921 ? 1464 LEU A HD21 1 
ATOM   83   H  HD22 . LEU A 1 5   ? -8.73767  -25.28409 -26.71821 1.000 18.16921 ? 1464 LEU A HD22 1 
ATOM   84   H  HD23 . LEU A 1 5   ? -8.33429  -26.43498 -27.73617 1.000 18.16921 ? 1464 LEU A HD23 1 
ATOM   85   N  N    . PRO A 1 6   ? -6.96043  -28.56579 -23.60051 1.000 12.85946 ? 1465 PRO A N    1 
ATOM   86   C  CA   . PRO A 1 6   ? -6.71735  -29.21133 -22.30415 1.000 12.99368 ? 1465 PRO A CA   1 
ATOM   87   C  C    . PRO A 1 6   ? -7.99673  -29.25020 -21.47472 1.000 12.64627 ? 1465 PRO A C    1 
ATOM   88   O  O    . PRO A 1 6   ? -9.02626  -28.69296 -21.85103 1.000 13.57270 ? 1465 PRO A O    1 
ATOM   89   C  CB   . PRO A 1 6   ? -5.65378  -28.30894 -21.67539 1.000 14.11487 ? 1465 PRO A CB   1 
ATOM   90   C  CG   . PRO A 1 6   ? -5.99715  -26.96301 -22.20805 1.000 14.59914 ? 1465 PRO A CG   1 
ATOM   91   C  CD   . PRO A 1 6   ? -6.42945  -27.18254 -23.64076 1.000 14.02012 ? 1465 PRO A CD   1 
ATOM   92   H  HA   . PRO A 1 6   ? -6.36697  -30.11037 -22.40342 1.000 15.59522 ? 1465 PRO A HA   1 
ATOM   93   H  HB2  . PRO A 1 6   ? -5.71838  -28.33396 -20.70787 1.000 16.94064 ? 1465 PRO A HB2  1 
ATOM   94   H  HB3  . PRO A 1 6   ? -4.76731  -28.58526 -21.95596 1.000 16.94064 ? 1465 PRO A HB3  1 
ATOM   95   H  HG2  . PRO A 1 6   ? -6.71937  -26.57938 -21.68639 1.000 17.52176 ? 1465 PRO A HG2  1 
ATOM   96   H  HG3  . PRO A 1 6   ? -5.21751  -26.38722 -22.16900 1.000 17.52176 ? 1465 PRO A HG3  1 
ATOM   97   H  HD2  . PRO A 1 6   ? -7.11930  -26.55103 -23.89803 1.000 16.82694 ? 1465 PRO A HD2  1 
ATOM   98   H  HD3  . PRO A 1 6   ? -5.67538  -27.11546 -24.24721 1.000 16.82694 ? 1465 PRO A HD3  1 
ATOM   99   N  N    . GLY A 1 7   ? -7.92944  -29.94417 -20.33997 1.000 12.73049 ? 1466 GLY A N    1 
ATOM   100  C  CA   . GLY A 1 7   ? -9.05836  -29.97973 -19.42733 1.000 12.38308 ? 1466 GLY A CA   1 
ATOM   101  C  C    . GLY A 1 7   ? -9.29371  -28.60633 -18.82498 1.000 11.76196 ? 1466 GLY A C    1 
ATOM   102  O  O    . GLY A 1 7   ? -8.44251  -28.09528 -18.08334 1.000 12.28570 ? 1466 GLY A O    1 
ATOM   103  H  H    . GLY A 1 7   ? -7.24583  -30.39744 -20.08147 1.000 15.27939 ? 1466 GLY A H    1 
ATOM   104  H  HA2  . GLY A 1 7   ? -9.85773  -30.25512 -19.90279 1.000 14.86250 ? 1466 GLY A HA2  1 
ATOM   105  H  HA3  . GLY A 1 7   ? -8.88354  -30.61063 -18.71157 1.000 14.86250 ? 1466 GLY A HA3  1 
ATOM   106  N  N    . LEU A 1 8   ? -10.44684 -28.02275 -19.09245 1.000 11.19610 ? 1467 LEU A N    1 
ATOM   107  C  CA   . LEU A 1 8   ? -10.70838 -26.66592 -18.63489 1.000 10.21704 ? 1467 LEU A CA   1 
ATOM   108  C  C    . LEU A 1 8   ? -11.21483 -26.66999 -17.19597 1.000 9.81172  ? 1467 LEU A C    1 
ATOM   109  O  O    . LEU A 1 8   ? -11.79832 -27.65601 -16.72283 1.000 10.44864 ? 1467 LEU A O    1 
ATOM   110  C  CB   . LEU A 1 8   ? -11.70678 -25.97725 -19.57453 1.000 10.73025 ? 1467 LEU A CB   1 
ATOM   111  C  CG   . LEU A 1 8   ? -11.31062 -25.93816 -21.04973 1.000 11.82249 ? 1467 LEU A CG   1 
ATOM   112  C  CD1  . LEU A 1 8   ? -12.36622 -25.21741 -21.88925 1.000 13.28056 ? 1467 LEU A CD1  1 
ATOM   113  C  CD2  . LEU A 1 8   ? -9.92497  -25.32559 -21.29468 1.000 11.70932 ? 1467 LEU A CD2  1 
ATOM   114  H  H    . LEU A 1 8   ? -11.09059 -28.38491 -19.53293 1.000 13.43812 ? 1467 LEU A H    1 
ATOM   115  H  HA   . LEU A 1 8   ? -9.88994  -26.14543 -18.64633 1.000 12.26324 ? 1467 LEU A HA   1 
ATOM   116  H  HB2  . LEU A 1 8   ? -12.55306 -26.44760 -19.51557 1.000 12.87910 ? 1467 LEU A HB2  1 
ATOM   117  H  HB3  . LEU A 1 8   ? -11.81626 -25.05926 -19.28092 1.000 12.87910 ? 1467 LEU A HB3  1 
ATOM   118  H  HG   . LEU A 1 8   ? -11.25670 -26.86171 -21.34137 1.000 14.18979 ? 1467 LEU A HG   1 
ATOM   119  H  HD11 . LEU A 1 8   ? -12.08773 -25.22174 -22.81840 1.000 15.93947 ? 1467 LEU A HD11 1 
ATOM   120  H  HD12 . LEU A 1 8   ? -13.21377 -25.67984 -21.79581 1.000 15.93947 ? 1467 LEU A HD12 1 
ATOM   121  H  HD13 . LEU A 1 8   ? -12.45115 -24.30413 -21.57363 1.000 15.93947 ? 1467 LEU A HD13 1 
ATOM   122  H  HD21 . LEU A 1 8   ? -9.76755  -25.27264 -22.25036 1.000 14.05398 ? 1467 LEU A HD21 1 
ATOM   123  H  HD22 . LEU A 1 8   ? -9.89902  -24.43748 -20.90547 1.000 14.05398 ? 1467 LEU A HD22 1 
ATOM   124  H  HD23 . LEU A 1 8   ? -9.25295  -25.88849 -20.87943 1.000 14.05398 ? 1467 LEU A HD23 1 
ATOM   125  N  N    . ILE A 1 9   ? -10.97436 -25.56187 -16.49801 1.000 9.46958  ? 1468 ILE A N    1 
ATOM   126  C  CA   . ILE A 1 9   ? -11.19544 -25.42458 -15.06598 1.000 9.26429  ? 1468 ILE A CA   1 
ATOM   127  C  C    . ILE A 1 9   ? -12.12681 -24.23971 -14.84455 1.000 9.30377  ? 1468 ILE A C    1 
ATOM   128  O  O    . ILE A 1 9   ? -11.85346 -23.14226 -15.34017 1.000 10.64077 ? 1468 ILE A O    1 
ATOM   129  C  CB   . ILE A 1 9   ? -9.86868  -25.19384 -14.30391 1.000 9.82225  ? 1468 ILE A CB   1 
ATOM   130  C  CG1  . ILE A 1 9   ? -8.87999  -26.32649 -14.58388 1.000 10.76184 ? 1468 ILE A CG1  1 
ATOM   131  C  CG2  . ILE A 1 9   ? -10.16495 -25.00172 -12.83338 1.000 10.51970 ? 1468 ILE A CG2  1 
ATOM   132  C  CD1  . ILE A 1 9   ? -7.47939  -26.00654 -14.10553 1.000 11.75143 ? 1468 ILE A CD1  1 
ATOM   133  H  H    . ILE A 1 9   ? -10.66718 -24.84141 -16.85323 1.000 11.36629 ? 1468 ILE A H    1 
ATOM   134  H  HA   . ILE A 1 9   ? -11.61638 -26.23155 -14.73057 1.000 11.11994 ? 1468 ILE A HA   1 
ATOM   135  H  HB   . ILE A 1 9   ? -9.43862  -24.38449 -14.62158 1.000 11.78950 ? 1468 ILE A HB   1 
ATOM   136  H  HG12 . ILE A 1 9   ? -9.17882  -27.12780 -14.12618 1.000 12.91700 ? 1468 ILE A HG12 1 
ATOM   137  H  HG13 . ILE A 1 9   ? -8.84276  -26.48496 -15.54012 1.000 12.91700 ? 1468 ILE A HG13 1 
ATOM   138  H  HG21 . ILE A 1 9   ? -9.33302  -25.03963 -12.33604 1.000 12.62644 ? 1468 ILE A HG21 1 
ATOM   139  H  HG22 . ILE A 1 9   ? -10.58708 -24.13764 -12.70654 1.000 12.62644 ? 1468 ILE A HG22 1 
ATOM   140  H  HG23 . ILE A 1 9   ? -10.76036 -25.70752 -12.53635 1.000 12.62644 ? 1468 ILE A HG23 1 
ATOM   141  H  HD11 . ILE A 1 9   ? -6.86717  -26.67462 -14.45158 1.000 14.10451 ? 1468 ILE A HD11 1 
ATOM   142  H  HD12 . ILE A 1 9   ? -7.22789  -25.12771 -14.43004 1.000 14.10451 ? 1468 ILE A HD12 1 
ATOM   143  H  HD13 . ILE A 1 9   ? -7.46679  -26.01711 -13.13567 1.000 14.10451 ? 1468 ILE A HD13 1 
ATOM   144  N  N    . ASP A 1 10  ? -13.21568 -24.46705 -14.11881 1.000 9.53537  ? 1469 ASP A N    1 
ATOM   145  C  CA   . ASP A 1 10  ? -14.13415 -23.40313 -13.71664 1.000 9.14585  ? 1469 ASP A CA   1 
ATOM   146  C  C    . ASP A 1 10  ? -14.00204 -23.19933 -12.20952 1.000 9.16165  ? 1469 ASP A C    1 
ATOM   147  O  O    . ASP A 1 10  ? -14.43271 -24.03506 -11.40725 1.000 9.95384  ? 1469 ASP A O    1 
ATOM   148  C  CB   . ASP A 1 10  ? -15.57852 -23.72034 -14.10811 1.000 9.39325  ? 1469 ASP A CB   1 
ATOM   149  C  CG   . ASP A 1 10  ? -16.50169 -22.52449 -13.94269 1.000 10.13545 ? 1469 ASP A CG   1 
ATOM   150  O  OD1  . ASP A 1 10  ? -16.17529 -21.60182 -13.16044 1.000 10.49075 ? 1469 ASP A OD1  1 
ATOM   151  O  OD2  . ASP A 1 10  ? -17.59522 -22.56203 -14.55552 1.000 11.53035 ? 1469 ASP A OD2  1 
ATOM   152  H  H    . ASP A 1 10  ? -13.45011 -25.24625 -13.84044 1.000 11.44525 ? 1469 ASP A H    1 
ATOM   153  H  HA   . ASP A 1 10  ? -13.87920 -22.58244 -14.16650 1.000 10.97782 ? 1469 ASP A HA   1 
ATOM   154  H  HB2  . ASP A 1 10  ? -15.60234 -23.99261 -15.03881 1.000 11.27470 ? 1469 ASP A HB2  1 
ATOM   155  H  HB3  . ASP A 1 10  ? -15.90986 -24.43674 -13.54429 1.000 11.27470 ? 1469 ASP A HB3  1 
ATOM   156  N  N    . VAL A 1 11  ? -13.39322 -22.07293 -11.81706 1.000 9.13533  ? 1470 VAL A N    1 
ATOM   157  C  CA   . VAL A 1 11  ? -13.14181 -21.81760 -10.41097 1.000 9.26955  ? 1470 VAL A CA   1 
ATOM   158  C  C    . VAL A 1 11  ? -14.31526 -21.18305 -9.66131  1.000 8.68791  ? 1470 VAL A C    1 
ATOM   159  O  O    . VAL A 1 11  ? -14.15253 -20.74859 -8.51416  1.000 9.81698  ? 1470 VAL A O    1 
ATOM   160  C  CB   . VAL A 1 11  ? -11.86062 -20.97030 -10.20690 1.000 9.40641  ? 1470 VAL A CB   1 
ATOM   161  C  CG1  . VAL A 1 11  ? -10.65735 -21.71675 -10.81464 1.000 10.07228 ? 1470 VAL A CG1  1 
ATOM   162  C  CG2  . VAL A 1 11  ? -11.99882 -19.56281 -10.80590 1.000 10.41706 ? 1470 VAL A CG2  1 
ATOM   163  H  H    . VAL A 1 11  ? -13.12237 -21.45285 -12.34786 1.000 10.96519 ? 1470 VAL A H    1 
ATOM   164  H  HA   . VAL A 1 11  ? -13.03549 -22.69840 -10.01881 1.000 11.12626 ? 1470 VAL A HA   1 
ATOM   165  H  HB   . VAL A 1 11  ? -11.71381 -20.84735 -9.25599  1.000 11.29049 ? 1470 VAL A HB   1 
ATOM   166  H  HG11 . VAL A 1 11  ? -9.84877  -21.21227 -10.63407 1.000 12.08953 ? 1470 VAL A HG11 1 
ATOM   167  H  HG12 . VAL A 1 11  ? -10.59517 -22.59676 -10.41138 1.000 12.08953 ? 1470 VAL A HG12 1 
ATOM   168  H  HG13 . VAL A 1 11  ? -10.78829 -21.80017 -11.77213 1.000 12.08953 ? 1470 VAL A HG13 1 
ATOM   169  H  HG21 . VAL A 1 11  ? -11.16081 -19.08766 -10.69249 1.000 12.50326 ? 1470 VAL A HG21 1 
ATOM   170  H  HG22 . VAL A 1 11  ? -12.20995 -19.64050 -11.74945 1.000 12.50326 ? 1470 VAL A HG22 1 
ATOM   171  H  HG23 . VAL A 1 11  ? -12.71094 -19.09209 -10.34526 1.000 12.50326 ? 1470 VAL A HG23 1 
ATOM   172  N  N    . HIS A 1 12  ? -15.51184 -21.16004 -10.26448 1.000 9.08269  ? 1471 HIS A N    1 
ATOM   173  C  CA   . HIS A 1 12  ? -16.64362 -20.55421 -9.55771  1.000 9.27745  ? 1471 HIS A CA   1 
ATOM   174  C  C    . HIS A 1 12  ? -17.96785 -21.19336 -9.97174  1.000 9.04847  ? 1471 HIS A C    1 
ATOM   175  O  O    . HIS A 1 12  ? -18.63533 -20.72683 -10.89285 1.000 9.42483  ? 1471 HIS A O    1 
ATOM   176  C  CB   . HIS A 1 12  ? -16.68714 -19.05231 -9.81087  1.000 8.76423  ? 1471 HIS A CB   1 
ATOM   177  C  CG   . HIS A 1 12  ? -17.56498 -18.31104 -8.87340  1.000 8.91688  ? 1471 HIS A CG   1 
ATOM   178  N  ND1  . HIS A 1 12  ? -17.19086 -17.10427 -8.33778  1.000 10.48285 ? 1471 HIS A ND1  1 
ATOM   179  C  CD2  . HIS A 1 12  ? -18.79923 -18.55895 -8.39726  1.000 8.05625  ? 1471 HIS A CD2  1 
ATOM   180  C  CE1  . HIS A 1 12  ? -18.13485 -16.65791 -7.53254  1.000 9.78804  ? 1471 HIS A CE1  1 
ATOM   181  N  NE2  . HIS A 1 12  ? -19.13123 -17.51321 -7.57433  1.000 8.99847  ? 1471 HIS A NE2  1 
ATOM   182  H  H    . HIS A 1 12  ? -15.68312 -21.47476 -11.04628 1.000 10.90202 ? 1471 HIS A H    1 
ATOM   183  H  HA   . HIS A 1 12  ? -16.52376 -20.75528 -8.61637  1.000 11.13573 ? 1471 HIS A HA   1 
ATOM   184  H  HB2  . HIS A 1 12  ? -15.78983 -18.69511 -9.72063  1.000 10.51987 ? 1471 HIS A HB2  1 
ATOM   185  H  HB3  . HIS A 1 12  ? -17.01703 -18.89741 -10.70980 1.000 10.51987 ? 1471 HIS A HB3  1 
ATOM   186  H  HD2  . HIS A 1 12  ? -19.32741 -19.29975 -8.58996  1.000 9.67030  ? 1471 HIS A HD2  1 
ATOM   187  H  HE1  . HIS A 1 12  ? -18.10137 -15.87841 -7.02643  1.000 11.74844 ? 1471 HIS A HE1  1 
ATOM   188  N  N    . VAL A 1 13  ? -18.35697 -22.24653 -9.25629  1.000 9.24850  ? 1472 VAL A N    1 
ATOM   189  C  CA   . VAL A 1 13  ? -19.64240 -22.89077 -9.51702  1.000 9.80119  ? 1472 VAL A CA   1 
ATOM   190  C  C    . VAL A 1 13  ? -20.38869 -23.09251 -8.20769  1.000 9.69066  ? 1472 VAL A C    1 
ATOM   191  O  O    . VAL A 1 13  ? -19.80113 -23.28360 -7.14566  1.000 10.28283 ? 1472 VAL A O    1 
ATOM   192  C  CB   . VAL A 1 13  ? -19.51279 -24.24161 -10.26720 1.000 10.14598 ? 1472 VAL A CB   1 
ATOM   193  C  CG1  . VAL A 1 13  ? -18.76883 -24.08711 -11.56543 1.000 11.28295 ? 1472 VAL A CG1  1 
ATOM   194  C  CG2  . VAL A 1 13  ? -18.91426 -25.31445 -9.38007  1.000 11.35401 ? 1472 VAL A CG2  1 
ATOM   195  H  H    . VAL A 1 13  ? -17.89856 -22.60213 -8.62147  1.000 11.10100 ? 1472 VAL A H    1 
ATOM   196  H  HA   . VAL A 1 13  ? -20.15764 -22.28840 -10.07609 1.000 11.76423 ? 1472 VAL A HA   1 
ATOM   197  H  HB   . VAL A 1 13  ? -20.40515 -24.54280 -10.49932 1.000 12.17797 ? 1472 VAL A HB   1 
ATOM   198  H  HG11 . VAL A 1 13  ? -18.71832 -24.95026 -12.00512 1.000 13.54234 ? 1472 VAL A HG11 1 
ATOM   199  H  HG12 . VAL A 1 13  ? -19.24405 -23.45632 -12.12860 1.000 13.54234 ? 1472 VAL A HG12 1 
ATOM   200  H  HG13 . VAL A 1 13  ? -17.87557 -23.75746 -11.38022 1.000 13.54234 ? 1472 VAL A HG13 1 
ATOM   201  H  HG21 . VAL A 1 13  ? -18.78471 -26.12089 -9.90330  1.000 13.62761 ? 1472 VAL A HG21 1 
ATOM   202  H  HG22 . VAL A 1 13  ? -18.06225 -25.00195 -9.03754  1.000 13.62761 ? 1472 VAL A HG22 1 
ATOM   203  H  HG23 . VAL A 1 13  ? -19.52162 -25.49128 -8.64471  1.000 13.62761 ? 1472 VAL A HG23 1 
ATOM   204  N  N    . HIS A 1 14  ? -21.71237 -23.07267 -8.29984  1.000 9.86963  ? 1473 HIS A N    1 
ATOM   205  C  CA   . HIS A 1 14  ? -22.61801 -23.40775 -7.19372  1.000 9.71434  ? 1473 HIS A CA   1 
ATOM   206  C  C    . HIS A 1 14  ? -23.33935 -24.69617 -7.57363  1.000 10.65919 ? 1473 HIS A C    1 
ATOM   207  O  O    . HIS A 1 14  ? -24.14695 -24.70140 -8.50316  1.000 11.40665 ? 1473 HIS A O    1 
ATOM   208  C  CB   . HIS A 1 14  ? -23.63057 -22.28172 -6.98879  1.000 9.19323  ? 1473 HIS A CB   1 
ATOM   209  C  CG   . HIS A 1 14  ? -23.01650 -20.97404 -6.58833  1.000 9.59591  ? 1473 HIS A CG   1 
ATOM   210  N  ND1  . HIS A 1 14  ? -22.85893 -20.61630 -5.27615  1.000 9.96964  ? 1473 HIS A ND1  1 
ATOM   211  C  CD2  . HIS A 1 14  ? -22.50495 -19.96325 -7.32753  1.000 9.16691  ? 1473 HIS A CD2  1 
ATOM   212  C  CE1  . HIS A 1 14  ? -22.30846 -19.41602 -5.21296  1.000 9.91173  ? 1473 HIS A CE1  1 
ATOM   213  N  NE2  . HIS A 1 14  ? -22.07058 -19.01103 -6.44270  1.000 9.08269  ? 1473 HIS A NE2  1 
ATOM   214  H  H    . HIS A 1 14  ? -22.13162 -22.86031 -9.02007  1.000 11.84635 ? 1473 HIS A H    1 
ATOM   215  H  HA   . HIS A 1 14  ? -22.11589 -23.54350 -6.37498  1.000 11.66001 ? 1473 HIS A HA   1 
ATOM   216  H  HB2  . HIS A 1 14  ? -24.11031 -22.14003 -7.81985  1.000 11.03467 ? 1473 HIS A HB2  1 
ATOM   217  H  HB3  . HIS A 1 14  ? -24.24924 -22.54356 -6.28908  1.000 11.03467 ? 1473 HIS A HB3  1 
ATOM   218  H  HD1  . HIS A 1 14  ? -23.08294 -21.09705 -4.59918  1.000 11.96636 ? 1473 HIS A HD1  1 
ATOM   219  H  HD2  . HIS A 1 14  ? -22.45729 -19.92243 -8.25541  1.000 11.00309 ? 1473 HIS A HD2  1 
ATOM   220  H  HE1  . HIS A 1 14  ? -22.12189 -18.94084 -4.43560  1.000 11.89688 ? 1473 HIS A HE1  1 
ATOM   221  N  N    . LEU A 1 15  ? -23.01861 -25.77955 -6.88168  1.000 10.59076 ? 1474 LEU A N    1 
ATOM   222  C  CA   . LEU A 1 15  ? -23.58157 -27.08523 -7.20906  1.000 11.18031 ? 1474 LEU A CA   1 
ATOM   223  C  C    . LEU A 1 15  ? -24.72332 -27.51140 -6.30076  1.000 11.69616 ? 1474 LEU A C    1 
ATOM   224  O  O    . LEU A 1 15  ? -25.30404 -28.57993 -6.53553  1.000 12.21991 ? 1474 LEU A O    1 
ATOM   225  C  CB   . LEU A 1 15  ? -22.49179 -28.16057 -7.27920  1.000 12.16990 ? 1474 LEU A CB   1 
ATOM   226  C  CG   . LEU A 1 15  ? -21.36127 -27.82662 -8.26880  1.000 13.66482 ? 1474 LEU A CG   1 
ATOM   227  C  CD1  . LEU A 1 15  ? -20.31660 -28.95266 -8.27564  1.000 15.44661 ? 1474 LEU A CD1  1 
ATOM   228  C  CD2  . LEU A 1 15  ? -21.90362 -27.56536 -9.65243  1.000 15.18078 ? 1474 LEU A CD2  1 
ATOM   229  H  H    . LEU A 1 15  ? -22.47515 -25.78606 -6.21519  1.000 12.71171 ? 1474 LEU A H    1 
ATOM   230  H  HA   . LEU A 1 15  ? -23.95644 -27.02650 -8.10176  1.000 13.41917 ? 1474 LEU A HA   1 
ATOM   231  H  HB2  . LEU A 1 15  ? -22.09670 -28.26222 -6.39916  1.000 14.60668 ? 1474 LEU A HB2  1 
ATOM   232  H  HB3  . LEU A 1 15  ? -22.89593 -28.99647 -7.55998  1.000 14.60668 ? 1474 LEU A HB3  1 
ATOM   233  H  HG   . LEU A 1 15  ? -20.92020 -27.01095 -7.98413  1.000 16.40058 ? 1474 LEU A HG   1 
ATOM   234  H  HD11 . LEU A 1 15  ? -19.60807 -28.72233 -8.89680  1.000 18.53873 ? 1474 LEU A HD11 1 
ATOM   235  H  HD12 . LEU A 1 15  ? -19.95345 -29.05197 -7.38169  1.000 18.53873 ? 1474 LEU A HD12 1 
ATOM   236  H  HD13 . LEU A 1 15  ? -20.74394 -29.77821 -8.55267  1.000 18.53873 ? 1474 LEU A HD13 1 
ATOM   237  H  HD21 . LEU A 1 15  ? -21.17112 -27.58664 -10.28796 1.000 18.21974 ? 1474 LEU A HD21 1 
ATOM   238  H  HD22 . LEU A 1 15  ? -22.55232 -28.25221 -9.87225  1.000 18.21974 ? 1474 LEU A HD22 1 
ATOM   239  H  HD23 . LEU A 1 15  ? -22.32793 -26.69319 -9.66582  1.000 18.21974 ? 1474 LEU A HD23 1 
ATOM   240  N  N    . ARG A 1 16  ? -25.07413 -26.71365 -5.28877  1.000 11.40402 ? 1475 ARG A N    1 
ATOM   241  C  CA   . ARG A 1 16  ? -26.33690 -26.75666 -4.53778  1.000 12.03831 ? 1475 ARG A CA   1 
ATOM   242  C  C    . ARG A 1 16  ? -26.49106 -27.96645 -3.62644  1.000 13.85431 ? 1475 ARG A C    1 
ATOM   243  O  O    . ARG A 1 16  ? -27.53311 -28.11106 -2.99480  1.000 16.80466 ? 1475 ARG A O    1 
ATOM   244  C  CB   . ARG A 1 16  ? -27.55916 -26.64076 -5.46608  1.000 11.69353 ? 1475 ARG A CB   1 
ATOM   245  C  CG   . ARG A 1 16  ? -27.51447 -25.42427 -6.38942  1.000 12.19885 ? 1475 ARG A CG   1 
ATOM   246  C  CD   . ARG A 1 16  ? -27.46789 -24.13401 -5.59387  1.000 12.35150 ? 1475 ARG A CD   1 
ATOM   247  N  NE   . ARG A 1 16  ? -27.70532 -23.00996 -6.48350  1.000 11.91461 ? 1475 ARG A NE   1 
ATOM   248  C  CZ   . ARG A 1 16  ? -27.36806 -21.75873 -6.20553  1.000 11.42508 ? 1475 ARG A CZ   1 
ATOM   249  N  NH1  . ARG A 1 16  ? -26.71931 -21.45431 -5.09002  1.000 12.21201 ? 1475 ARG A NH1  1 
ATOM   250  N  NH2  . ARG A 1 16  ? -27.67680 -20.79152 -7.07146  1.000 11.76985 ? 1475 ARG A NH2  1 
ATOM   251  H  H    . ARG A 1 16  ? -24.55648 -26.09186 -4.99720  1.000 13.68762 ? 1475 ARG A H    1 
ATOM   252  H  HA   . ARG A 1 16  ? -26.33824 -25.99151 -3.94158  1.000 14.44876 ? 1475 ARG A HA   1 
ATOM   253  H  HB2  . ARG A 1 16  ? -27.60488 -27.43395 -6.02255  1.000 14.03503 ? 1475 ARG A HB2  1 
ATOM   254  H  HB3  . ARG A 1 16  ? -28.35903 -26.57078 -4.92183  1.000 14.03503 ? 1475 ARG A HB3  1 
ATOM   255  H  HG2  . ARG A 1 16  ? -26.72078 -25.47016 -6.94516  1.000 14.64142 ? 1475 ARG A HG2  1 
ATOM   256  H  HG3  . ARG A 1 16  ? -28.30888 -25.41238 -6.94589  1.000 14.64142 ? 1475 ARG A HG3  1 
ATOM   257  H  HD2  . ARG A 1 16  ? -28.15585 -24.14394 -4.91012  1.000 14.82460 ? 1475 ARG A HD2  1 
ATOM   258  H  HD3  . ARG A 1 16  ? -26.59460 -24.03121 -5.18436  1.000 14.82460 ? 1475 ARG A HD3  1 
ATOM   259  H  HE   . ARG A 1 16  ? -28.08856 -23.16630 -7.23734  1.000 14.30032 ? 1475 ARG A HE   1 
ATOM   260  H  HH11 . ARG A 1 16  ? -26.50991 -22.07394 -4.53162  1.000 14.65721 ? 1475 ARG A HH11 1 
ATOM   261  H  HH12 . ARG A 1 16  ? -26.50791 -20.63722 -4.92485  1.000 14.65721 ? 1475 ARG A HH12 1 
ATOM   262  H  HH21 . ARG A 1 16  ? -28.09028 -20.98320 -7.80076  1.000 14.12662 ? 1475 ARG A HH21 1 
ATOM   263  H  HH22 . ARG A 1 16  ? -27.46229 -19.97650 -6.90022  1.000 14.12662 ? 1475 ARG A HH22 1 
ATOM   264  N  N    . GLU A 1 17  ? -25.52078 -28.84894 -3.54688  1.000 13.95959 ? 1476 GLU A N    1 
ATOM   265  C  CA   . GLU A 1 17  ? -25.56411 -29.99865 -2.68491  1.000 13.96485 ? 1476 GLU A CA   1 
ATOM   266  C  C    . GLU A 1 17  ? -24.47524 -29.81621 -1.64220  1.000 15.13341 ? 1476 GLU A C    1 
ATOM   267  O  O    . GLU A 1 17  ? -23.32309 -29.56050 -2.00066  1.000 16.22302 ? 1476 GLU A O    1 
ATOM   268  C  CB   . GLU A 1 17  ? -25.30261 -31.26407 -3.51200  1.000 13.32004 ? 1476 GLU A CB   1 
ATOM   269  C  CG   . GLU A 1 17  ? -25.38706 -32.55289 -2.69469  1.000 13.75430 ? 1476 GLU A CG   1 
ATOM   270  C  CD   . GLU A 1 17  ? -25.30379 -33.83087 -3.48908  1.000 14.61230 ? 1476 GLU A CD   1 
ATOM   271  O  OE1  . GLU A 1 17  ? -25.04055 -33.79260 -4.69701  1.000 14.90970 ? 1476 GLU A OE1  1 
ATOM   272  O  OE2  . GLU A 1 17  ? -25.49342 -34.89266 -2.87190  1.000 15.97035 ? 1476 GLU A OE2  1 
ATOM   273  H  H    . GLU A 1 17  ? -24.79433 -28.79914 -4.00448  1.000 16.75430 ? 1476 GLU A H    1 
ATOM   274  H  HA   . GLU A 1 17  ? -26.42504 -30.09832 -2.24929  1.000 16.76062 ? 1476 GLU A HA   1 
ATOM   275  H  HB2  . GLU A 1 17  ? -25.96323 -31.31714 -4.22028  1.000 15.98684 ? 1476 GLU A HB2  1 
ATOM   276  H  HB3  . GLU A 1 17  ? -24.41190 -31.21086 -3.89240  1.000 15.98684 ? 1476 GLU A HB3  1 
ATOM   277  H  HG2  . GLU A 1 17  ? -24.65433 -32.56026 -2.05912  1.000 16.50796 ? 1476 GLU A HG2  1 
ATOM   278  H  HG3  . GLU A 1 17  ? -26.23494 -32.56100 -2.22360  1.000 16.50796 ? 1476 GLU A HG3  1 
ATOM   279  N  N    . PRO A 1 18  ? -24.79257 -29.88510 -0.35574  1.000 15.89666 ? 1477 PRO A N    1 
ATOM   280  C  CA   . PRO A 1 18  ? -26.08985 -30.23855 0.23210   1.000 15.70717 ? 1477 PRO A CA   1 
ATOM   281  C  C    . PRO A 1 18  ? -27.16008 -29.15452 0.25005   1.000 15.92561 ? 1477 PRO A C    1 
ATOM   282  O  O    . PRO A 1 18  ? -26.86370 -27.95958 0.26156   1.000 15.71506 ? 1477 PRO A O    1 
ATOM   283  C  CB   . PRO A 1 18  ? -25.68599 -30.62817 1.67276   1.000 16.49673 ? 1477 PRO A CB   1 
ATOM   284  C  CG   . PRO A 1 18  ? -24.55545 -29.66189 1.97879   1.000 17.22314 ? 1477 PRO A CG   1 
ATOM   285  C  CD   . PRO A 1 18  ? -23.77220 -29.61944 0.67623   1.000 16.90205 ? 1477 PRO A CD   1 
ATOM   286  H  HA   . PRO A 1 18  ? -26.44492 -30.98400 -0.27695  1.000 18.85140 ? 1477 PRO A HA   1 
ATOM   287  H  HB2  . PRO A 1 18  ? -26.43289 -30.50443 2.27916   1.000 19.79888 ? 1477 PRO A HB2  1 
ATOM   288  H  HB3  . PRO A 1 18  ? -25.38366 -31.54937 1.70243   1.000 19.79888 ? 1477 PRO A HB3  1 
ATOM   289  H  HG2  . PRO A 1 18  ? -24.91031 -28.78828 2.20633   1.000 20.67056 ? 1477 PRO A HG2  1 
ATOM   290  H  HG3  . PRO A 1 18  ? -24.01119 -29.99898 2.70753   1.000 20.67056 ? 1477 PRO A HG3  1 
ATOM   291  H  HD2  . PRO A 1 18  ? -23.37054 -28.74627 0.54531   1.000 20.28525 ? 1477 PRO A HD2  1 
ATOM   292  H  HD3  . PRO A 1 18  ? -23.08622 -30.30516 0.66547   1.000 20.28525 ? 1477 PRO A HD3  1 
ATOM   293  N  N    . GLY A 1 19  ? -28.42851 -29.57403 0.25275   1.000 16.15985 ? 1478 GLY A N    1 
ATOM   294  C  CA   . GLY A 1 19  ? -29.50213 -28.73001 0.73225   1.000 17.23103 ? 1478 GLY A CA   1 
ATOM   295  C  C    . GLY A 1 19  ? -30.33907 -28.03583 -0.31767  1.000 17.82584 ? 1478 GLY A C    1 
ATOM   296  O  O    . GLY A 1 19  ? -31.41902 -27.52583 0.01762   1.000 19.25232 ? 1478 GLY A O    1 
ATOM   297  H  H    . GLY A 1 19  ? -28.68366 -30.34826 -0.02125  1.000 19.39462 ? 1478 GLY A H    1 
ATOM   298  H  HA2  . GLY A 1 19  ? -30.10222 -29.27525 1.26471   1.000 20.68004 ? 1478 GLY A HA2  1 
ATOM   299  H  HA3  . GLY A 1 19  ? -29.11765 -28.04070 1.29611   1.000 20.68004 ? 1478 GLY A HA3  1 
ATOM   300  N  N    . GLY A 1 20  ? -29.90783 -28.02555 -1.56790  1.000 16.59938 ? 1479 GLY A N    1 
ATOM   301  C  CA   . GLY A 1 20  ? -30.66491 -27.39025 -2.62035  1.000 15.79665 ? 1479 GLY A CA   1 
ATOM   302  C  C    . GLY A 1 20  ? -30.74391 -28.23427 -3.86424  1.000 15.25185 ? 1479 GLY A C    1 
ATOM   303  O  O    . GLY A 1 20  ? -30.68586 -27.71165 -4.98443  1.000 15.01498 ? 1479 GLY A O    1 
ATOM   304  H  H    . GLY A 1 20  ? -29.17196 -28.38420 -1.83146  1.000 19.92205 ? 1479 GLY A H    1 
ATOM   305  H  HA2  . GLY A 1 20  ? -31.56766 -27.22122 -2.30831  1.000 18.95878 ? 1479 GLY A HA2  1 
ATOM   306  H  HA3  . GLY A 1 20  ? -30.24702 -26.54570 -2.85055  1.000 18.95878 ? 1479 GLY A HA3  1 
ATOM   307  N  N    . THR A 1 21  ? -30.91023 -29.54464 -3.67216  1.000 15.21237 ? 1480 THR A N    1 
ATOM   308  C  CA   . THR A 1 21  ? -30.64333 -30.48731 -4.74997  1.000 14.97813 ? 1480 THR A CA   1 
ATOM   309  C  C    . THR A 1 21  ? -31.72556 -30.50315 -5.82490  1.000 14.63072 ? 1480 THR A C    1 
ATOM   310  O  O    . THR A 1 21  ? -31.50682 -31.11138 -6.87219  1.000 15.55452 ? 1480 THR A O    1 
ATOM   311  C  CB   . THR A 1 21  ? -30.38043 -31.90247 -4.21385  1.000 16.09142 ? 1480 THR A CB   1 
ATOM   312  O  OG1  . THR A 1 21  ? -31.51267 -32.38236 -3.48497  1.000 18.01270 ? 1480 THR A OG1  1 
ATOM   313  C  CG2  . THR A 1 21  ? -29.11947 -31.94971 -3.31512  1.000 16.80993 ? 1480 THR A CG2  1 
ATOM   314  H  H    . THR A 1 21  ? -31.17300 -29.90428 -2.93649  1.000 18.25764 ? 1480 THR A H    1 
ATOM   315  H  HA   . THR A 1 21  ? -29.82047 -30.20851 -5.18134  1.000 17.97656 ? 1480 THR A HA   1 
ATOM   316  H  HB   . THR A 1 21  ? -30.22301 -32.48820 -4.97084  1.000 19.31251 ? 1480 THR A HB   1 
ATOM   317  H  HG1  . THR A 1 21  ? -31.68036 -31.86734 -2.84291  1.000 21.61804 ? 1480 THR A HG1  1 
ATOM   318  H  HG21 . THR A 1 21  ? -28.97009 -32.85500 -3.00042  1.000 20.17471 ? 1480 THR A HG21 1 
ATOM   319  H  HG22 . THR A 1 21  ? -28.34259 -31.65902 -3.81797  1.000 20.17471 ? 1480 THR A HG22 1 
ATOM   320  H  HG23 . THR A 1 21  ? -29.23562 -31.36546 -2.54957  1.000 20.17471 ? 1480 THR A HG23 1 
ATOM   321  N  N    . HIS A 1 22  ? -32.86817 -29.83415 -5.61918  1.000 14.75179 ? 1481 HIS A N    1 
ATOM   322  C  CA   . HIS A 1 22  ? -33.81018 -29.64212 -6.71779  1.000 15.04656 ? 1481 HIS A CA   1 
ATOM   323  C  C    . HIS A 1 22  ? -33.29617 -28.62209 -7.73100  1.000 14.72020 ? 1481 HIS A C    1 
ATOM   324  O  O    . HIS A 1 22  ? -33.74809 -28.61233 -8.88027  1.000 15.19921 ? 1481 HIS A O    1 
ATOM   325  C  CB   . HIS A 1 22  ? -35.17144 -29.17117 -6.19492  1.000 15.60189 ? 1481 HIS A CB   1 
ATOM   326  C  CG   . HIS A 1 22  ? -35.11900 -27.83604 -5.51843  1.000 15.67822 ? 1481 HIS A CG   1 
ATOM   327  N  ND1  . HIS A 1 22  ? -34.53342 -27.65884 -4.28357  1.000 16.57306 ? 1481 HIS A ND1  1 
ATOM   328  C  CD2  . HIS A 1 22  ? -35.52966 -26.60970 -5.91917  1.000 15.76507 ? 1481 HIS A CD2  1 
ATOM   329  C  CE1  . HIS A 1 22  ? -34.60833 -26.38412 -3.94145  1.000 16.39672 ? 1481 HIS A CE1  1 
ATOM   330  N  NE2  . HIS A 1 22  ? -35.21296 -25.72528 -4.91562  1.000 16.19933 ? 1481 HIS A NE2  1 
ATOM   331  H  H    . HIS A 1 22  ? -33.11178 -29.49129 -4.86905  1.000 17.70494 ? 1481 HIS A H    1 
ATOM   332  H  HA   . HIS A 1 22  ? -33.93720 -30.49715 -7.15789  1.000 18.05867 ? 1481 HIS A HA   1 
ATOM   333  H  HB2  . HIS A 1 22  ? -35.78712 -29.10262 -6.94133  1.000 18.72506 ? 1481 HIS A HB2  1 
ATOM   334  H  HB3  . HIS A 1 22  ? -35.50079 -29.81806 -5.55152  1.000 18.72506 ? 1481 HIS A HB3  1 
ATOM   335  H  HD2  . HIS A 1 22  ? -35.94818 -26.40395 -6.72378  1.000 18.92088 ? 1481 HIS A HD2  1 
ATOM   336  H  HE1  . HIS A 1 22  ? -34.28990 -26.01364 -3.15009  1.000 19.67886 ? 1481 HIS A HE1  1 
ATOM   337  H  HE2  . HIS A 1 22  ? -35.38056 -24.88179 -4.92053  1.000 19.44199 ? 1481 HIS A HE2  1 
ATOM   338  N  N    . LYS A 1 23  ? -32.33732 -27.78010 -7.34150  1.000 13.47269 ? 1482 LYS A N    1 
ATOM   339  C  CA   . LYS A 1 23  ? -31.75110 -26.81175 -8.25106  1.000 13.23845 ? 1482 LYS A CA   1 
ATOM   340  C  C    . LYS A 1 23  ? -30.61293 -27.38182 -9.07619  1.000 12.97526 ? 1482 LYS A C    1 
ATOM   341  O  O    . LYS A 1 23  ? -30.39651 -26.94793 -10.21776 1.000 12.32518 ? 1482 LYS A O    1 
ATOM   342  C  CB   . LYS A 1 23  ? -31.14190 -25.66112 -7.44425  1.000 13.25687 ? 1482 LYS A CB   1 
ATOM   343  C  CG   . LYS A 1 23  ? -32.11868 -24.89962 -6.55192  1.000 13.40952 ? 1482 LYS A CG   1 
ATOM   344  C  CD   . LYS A 1 23  ? -31.32899 -23.89342 -5.68308  1.000 13.78588 ? 1482 LYS A CD   1 
ATOM   345  C  CE   . LYS A 1 23  ? -32.19656 -23.15269 -4.69895  1.000 13.86221 ? 1482 LYS A CE   1 
ATOM   346  N  NZ   . LYS A 1 23  ? -33.01984 -22.11841 -5.36042  1.000 14.38595 ? 1482 LYS A NZ   1 
ATOM   347  H  H    . LYS A 1 23  ? -32.00971 -27.75389 -6.54678  1.000 16.17002 ? 1482 LYS A H    1 
ATOM   348  H  HA   . LYS A 1 23  ? -32.45527 -26.49392 -8.83760  1.000 15.88894 ? 1482 LYS A HA   1 
ATOM   349  H  HB2  . LYS A 1 23  ? -30.44847 -26.02349 -6.87088  1.000 15.91104 ? 1482 LYS A HB2  1 
ATOM   350  H  HB3  . LYS A 1 23  ? -30.75862 -25.02193 -8.06508  1.000 15.91104 ? 1482 LYS A HB3  1 
ATOM   351  H  HG2  . LYS A 1 23  ? -32.75497 -24.41252 -7.09853  1.000 16.09422 ? 1482 LYS A HG2  1 
ATOM   352  H  HG3  . LYS A 1 23  ? -32.58670 -25.51887 -5.97020  1.000 16.09422 ? 1482 LYS A HG3  1 
ATOM   353  H  HD2  . LYS A 1 23  ? -30.65229 -24.37391 -5.18097  1.000 16.54586 ? 1482 LYS A HD2  1 
ATOM   354  H  HD3  . LYS A 1 23  ? -30.90945 -23.23826 -6.26244  1.000 16.54586 ? 1482 LYS A HD3  1 
ATOM   355  H  HE2  . LYS A 1 23  ? -32.79231 -23.78104 -4.26173  1.000 16.63745 ? 1482 LYS A HE2  1 
ATOM   356  H  HE3  . LYS A 1 23  ? -31.63298 -22.71685 -4.04068  1.000 16.63745 ? 1482 LYS A HE3  1 
ATOM   357  H  HZ1  . LYS A 1 23  ? -33.85541 -22.15377 -5.05599  1.000 17.26594 ? 1482 LYS A HZ1  1 
ATOM   358  H  HZ2  . LYS A 1 23  ? -32.68559 -21.31061 -5.19360  1.000 17.26594 ? 1482 LYS A HZ2  1 
ATOM   359  H  HZ3  . LYS A 1 23  ? -33.02713 -22.25191 -6.24032  1.000 17.26594 ? 1482 LYS A HZ3  1 
ATOM   360  N  N    . GLU A 1 24  ? -29.88458 -28.32895 -8.48633  1.000 13.02790 ? 1483 GLU A N    1 
ATOM   361  C  CA   . GLU A 1 24  ? -28.67318 -28.92708 -9.02514  1.000 12.07252 ? 1483 GLU A CA   1 
ATOM   362  C  C    . GLU A 1 24  ? -28.15693 -29.86476 -7.94961  1.000 12.14362 ? 1483 GLU A C    1 
ATOM   363  O  O    . GLU A 1 24  ? -28.41106 -29.65417 -6.76951  1.000 12.36992 ? 1483 GLU A O    1 
ATOM   364  C  CB   . GLU A 1 24  ? -27.60929 -27.84835 -9.28603  1.000 11.96461 ? 1483 GLU A CB   1 
ATOM   365  C  CG   . GLU A 1 24  ? -26.55350 -28.29846 -10.30905 1.000 11.15925 ? 1483 GLU A CG   1 
ATOM   366  C  CD   . GLU A 1 24  ? -27.10657 -28.18869 -11.72273 1.000 11.11715 ? 1483 GLU A CD   1 
ATOM   367  O  OE1  . GLU A 1 24  ? -27.77785 -29.17312 -12.15618 1.000 11.90144 ? 1483 GLU A OE1  1 
ATOM   368  O  OE2  . GLU A 1 24  ? -26.89010 -27.16769 -12.39500 1.000 12.04094 ? 1483 GLU A OE2  1 
ATOM   369  H  H    . GLU A 1 24  ? -30.08779 -28.66297 -7.72035  1.000 15.63627 ? 1483 GLU A H    1 
ATOM   370  H  HA   . GLU A 1 24  ? -28.84462 -29.38304 -9.86396  1.000 14.48983 ? 1483 GLU A HA   1 
ATOM   371  H  HB2  . GLU A 1 24  ? -28.04334 -27.05246 -9.63108  1.000 14.36033 ? 1483 GLU A HB2  1 
ATOM   372  H  HB3  . GLU A 1 24  ? -27.15481 -27.64403 -8.45380  1.000 14.36033 ? 1483 GLU A HB3  1 
ATOM   373  H  HG2  . GLU A 1 24  ? -25.76929 -27.73202 -10.23795 1.000 13.39390 ? 1483 GLU A HG2  1 
ATOM   374  H  HG3  . GLU A 1 24  ? -26.31144 -29.22272 -10.14159 1.000 13.39390 ? 1483 GLU A HG3  1 
ATOM   375  N  N    . ASP A 1 25  ? -27.41791 -30.90415 -8.32479  1.000 29.53773 ? 1484 ASP A N    1 
ATOM   376  C  CA   . ASP A 1 25  ? -26.63158 -31.64670 -7.34393  1.000 30.03783 ? 1484 ASP A CA   1 
ATOM   377  C  C    . ASP A 1 25  ? -25.25419 -31.88036 -7.94306  1.000 29.57458 ? 1484 ASP A C    1 
ATOM   378  O  O    . ASP A 1 25  ? -24.97227 -31.46490 -9.06646  1.000 30.01941 ? 1484 ASP A O    1 
ATOM   379  C  CB   . ASP A 1 25  ? -27.35476 -32.89404 -6.81852  1.000 30.04836 ? 1484 ASP A CB   1 
ATOM   380  C  CG   . ASP A 1 25  ? -27.70360 -33.90722 -7.89703  1.000 30.05625 ? 1484 ASP A CG   1 
ATOM   381  O  OD1  . ASP A 1 25  ? -27.20793 -33.86717 -9.03360  1.000 30.03257 ? 1484 ASP A OD1  1 
ATOM   382  O  OD2  . ASP A 1 25  ? -28.56490 -34.75454 -7.57791  1.000 30.04836 ? 1484 ASP A OD2  1 
ATOM   383  H  H    . ASP A 1 25  ? -27.35624 -31.19510 -9.13173  1.000 35.44807 ? 1484 ASP A H    1 
ATOM   384  H  HA   . ASP A 1 25  ? -26.49648 -31.11412 -6.54455  1.000 36.04819 ? 1484 ASP A HA   1 
ATOM   385  H  HB2  . ASP A 1 25  ? -26.78237 -33.33673 -6.17253  1.000 36.06083 ? 1484 ASP A HB2  1 
ATOM   386  H  HB3  . ASP A 1 25  ? -28.18247 -32.61845 -6.39443  1.000 36.06083 ? 1484 ASP A HB3  1 
ATOM   387  N  N    . PHE A 1 26  ? -24.37780 -32.54257 -7.18828  1.000 13.37798 ? 1485 PHE A N    1 
ATOM   388  C  CA   . PHE A 1 26  ? -23.04645 -32.77315 -7.74041  1.000 12.84630 ? 1485 PHE A CA   1 
ATOM   389  C  C    . PHE A 1 26  ? -23.12075 -33.54687 -9.05130  1.000 12.88841 ? 1485 PHE A C    1 
ATOM   390  O  O    . PHE A 1 26  ? -22.39329 -33.24812 -10.00515 1.000 12.87788 ? 1485 PHE A O    1 
ATOM   391  C  CB   . PHE A 1 26  ? -22.13569 -33.50161 -6.75442  1.000 13.73851 ? 1485 PHE A CB   1 
ATOM   392  C  CG   . PHE A 1 26  ? -21.58545 -32.63212 -5.67140  1.000 15.31502 ? 1485 PHE A CG   1 
ATOM   393  C  CD1  . PHE A 1 26  ? -20.66858 -31.64571 -5.95718  1.000 17.25998 ? 1485 PHE A CD1  1 
ATOM   394  C  CD2  . PHE A 1 26  ? -21.97340 -32.80454 -4.36807  1.000 16.14406 ? 1485 PHE A CD2  1 
ATOM   395  C  CE1  . PHE A 1 26  ? -20.15764 -30.83666 -4.93288  1.000 18.02586 ? 1485 PHE A CE1  1 
ATOM   396  C  CE2  . PHE A 1 26  ? -21.47588 -32.01054 -3.36763  1.000 17.23103 ? 1485 PHE A CE2  1 
ATOM   397  C  CZ   . PHE A 1 26  ? -20.57647 -31.03021 -3.64675  1.000 17.68372 ? 1485 PHE A CZ   1 
ATOM   398  H  H    . PHE A 1 26  ? -24.52125 -32.85110 -6.39845  1.000 16.05637 ? 1485 PHE A H    1 
ATOM   399  H  HA   . PHE A 1 26  ? -22.64850 -31.90408 -7.90549  1.000 15.41836 ? 1485 PHE A HA   1 
ATOM   400  H  HB2  . PHE A 1 26  ? -22.64206 -34.21288 -6.33182  1.000 16.48901 ? 1485 PHE A HB2  1 
ATOM   401  H  HB3  . PHE A 1 26  ? -21.38478 -33.87389 -7.24274  1.000 16.48901 ? 1485 PHE A HB3  1 
ATOM   402  H  HD1  . PHE A 1 26  ? -20.38689 -31.51555 -6.83389  1.000 20.71478 ? 1485 PHE A HD1  1 
ATOM   403  H  HD2  . PHE A 1 26  ? -22.58554 -33.47263 -4.15869  1.000 19.37567 ? 1485 PHE A HD2  1 
ATOM   404  H  HE1  . PHE A 1 26  ? -19.53708 -30.17190 -5.12757  1.000 21.63383 ? 1485 PHE A HE1  1 
ATOM   405  H  HE2  . PHE A 1 26  ? -21.75590 -32.14358 -2.49083  1.000 20.68004 ? 1485 PHE A HE2  1 
ATOM   406  H  HZ   . PHE A 1 26  ? -20.24680 -30.49221 -2.96354  1.000 21.22326 ? 1485 PHE A HZ   1 
ATOM   407  N  N    . ALA A 1 27  ? -23.98420 -34.56941 -9.11132  1.000 12.78840 ? 1486 ALA A N    1 
ATOM   408  C  CA   . ALA A 1 27  ? -24.07893 -35.37301 -10.31407 1.000 13.02264 ? 1486 ALA A CA   1 
ATOM   409  C  C    . ALA A 1 27  ? -24.57093 -34.56998 -11.50865 1.000 13.29635 ? 1486 ALA A C    1 
ATOM   410  O  O    . ALA A 1 27  ? -24.01213 -34.68025 -12.60629 1.000 14.38859 ? 1486 ALA A O    1 
ATOM   411  C  CB   . ALA A 1 27  ? -24.99959 -36.56656 -10.06602 1.000 14.20172 ? 1486 ALA A CB   1 
ATOM   412  H  H    . ALA A 1 27  ? -24.51302 -34.80732 -8.47623  1.000 15.34887 ? 1486 ALA A H    1 
ATOM   413  H  HA   . ALA A 1 27  ? -23.19127 -35.69947 -10.52942 1.000 15.62996 ? 1486 ALA A HA   1 
ATOM   414  H  HB1  . ALA A 1 27  ? -25.05886 -37.09381 -10.87806 1.000 17.04486 ? 1486 ALA A HB1  1 
ATOM   415  H  HB2  . ALA A 1 27  ? -24.63186 -37.10520 -9.34801  1.000 17.04486 ? 1486 ALA A HB2  1 
ATOM   416  H  HB3  . ALA A 1 27  ? -25.87903 -36.24089 -9.81817  1.000 17.04486 ? 1486 ALA A HB3  1 
ATOM   417  N  N    . SER A 1 28  ? -25.58753 -33.71914 -11.32476 1.000 13.23845 ? 1487 SER A N    1 
ATOM   418  C  CA   . SER A 1 28  ? -26.11604 -33.00519 -12.48832 1.000 12.59627 ? 1487 SER A CA   1 
ATOM   419  C  C    . SER A 1 28  ? -25.22803 -31.83106 -12.86504 1.000 11.69090 ? 1487 SER A C    1 
ATOM   420  O  O    . SER A 1 28  ? -25.04475 -31.53883 -14.05049 1.000 12.25412 ? 1487 SER A O    1 
ATOM   421  C  CB   . SER A 1 28  ? -27.55008 -32.53401 -12.23654 1.000 12.81208 ? 1487 SER A CB   1 
ATOM   422  O  OG   . SER A 1 28  ? -27.63793 -31.61205 -11.16661 1.000 13.09633 ? 1487 SER A OG   1 
ATOM   423  H  H    . SER A 1 28  ? -25.96900 -33.54704 -10.57345 1.000 15.88894 ? 1487 SER A H    1 
ATOM   424  H  HA   . SER A 1 28  ? -26.14430 -33.62073 -13.23747 1.000 15.11832 ? 1487 SER A HA   1 
ATOM   425  H  HB2  . SER A 1 28  ? -27.88033 -32.10544 -13.04162 1.000 15.37730 ? 1487 SER A HB2  1 
ATOM   426  H  HB3  . SER A 1 28  ? -28.09643 -33.30685 -12.02411 1.000 15.37730 ? 1487 SER A HB3  1 
ATOM   427  H  HG   . SER A 1 28  ? -27.19953 -30.91885 -11.34796 1.000 15.71839 ? 1487 SER A HG   1 
ATOM   428  N  N    . GLY A 1 29  ? -24.70380 -31.15463 -11.85166 1.000 11.68563 ? 1488 GLY A N    1 
ATOM   429  C  CA   . GLY A 1 29  ? -23.87000 -29.99219 -12.11171 1.000 10.93817 ? 1488 GLY A CA   1 
ATOM   430  C  C    . GLY A 1 29  ? -22.55520 -30.37631 -12.76379 1.000 10.78816 ? 1488 GLY A C    1 
ATOM   431  O  O    . GLY A 1 29  ? -22.04531 -29.65116 -13.61245 1.000 11.15136 ? 1488 GLY A O    1 
ATOM   432  H  H    . GLY A 1 29  ? -24.81303 -31.34381 -11.01986 1.000 14.02555 ? 1488 GLY A H    1 
ATOM   433  H  HA2  . GLY A 1 29  ? -24.34022 -29.38261 -12.70180 1.000 13.12861 ? 1488 GLY A HA2  1 
ATOM   434  H  HA3  . GLY A 1 29  ? -23.67862 -29.53822 -11.27613 1.000 13.12861 ? 1488 GLY A HA3  1 
ATOM   435  N  N    . THR A 1 30  ? -21.99474 -31.53402 -12.38602 1.000 11.31190 ? 1489 THR A N    1 
ATOM   436  C  CA   . THR A 1 30  ? -20.76452 -31.97361 -13.03685 1.000 11.88302 ? 1489 THR A CA   1 
ATOM   437  C  C    . THR A 1 30  ? -21.03149 -32.60558 -14.40215 1.000 12.32518 ? 1489 THR A C    1 
ATOM   438  O  O    . THR A 1 30  ? -20.15315 -32.58466 -15.26690 1.000 12.04883 ? 1489 THR A O    1 
ATOM   439  C  CB   . THR A 1 30  ? -19.92572 -32.90751 -12.15247 1.000 11.97251 ? 1489 THR A CB   1 
ATOM   440  O  OG1  . THR A 1 30  ? -20.64906 -34.11637 -11.84407 1.000 12.40940 ? 1489 THR A OG1  1 
ATOM   441  C  CG2  . THR A 1 30  ? -19.47021 -32.20245 -10.87544 1.000 12.72523 ? 1489 THR A CG2  1 
ATOM   442  H  H    . THR A 1 30  ? -22.29925 -32.06019 -11.77772 1.000 13.57708 ? 1489 THR A H    1 
ATOM   443  H  HA   . THR A 1 30  ? -20.21388 -31.18622 -13.16994 1.000 14.26243 ? 1489 THR A HA   1 
ATOM   444  H  HB   . THR A 1 30  ? -19.12685 -33.16000 -12.64131 1.000 14.36981 ? 1489 THR A HB   1 
ATOM   445  H  HG1  . THR A 1 30  ? -21.35531 -33.93061 -11.42897 1.000 14.89408 ? 1489 THR A HG1  1 
ATOM   446  H  HG21 . THR A 1 30  ? -18.93923 -32.80720 -10.33393 1.000 15.27307 ? 1489 THR A HG21 1 
ATOM   447  H  HG22 . THR A 1 30  ? -18.93336 -31.42599 -11.09861 1.000 15.27307 ? 1489 THR A HG22 1 
ATOM   448  H  HG23 . THR A 1 30  ? -20.24139 -31.91496 -10.36208 1.000 15.27307 ? 1489 THR A HG23 1 
ATOM   449  N  N    . ALA A 1 31  ? -22.22103 -33.17050 -14.63422 1.000 12.20675 ? 1490 ALA A N    1 
ATOM   450  C  CA   . ALA A 1 31  ? -22.59896 -33.49962 -15.99994 1.000 12.17516 ? 1490 ALA A CA   1 
ATOM   451  C  C    . ALA A 1 31  ? -22.63104 -32.24420 -16.87062 1.000 11.59878 ? 1490 ALA A C    1 
ATOM   452  O  O    . ALA A 1 31  ? -22.11943 -32.24071 -17.99972 1.000 11.99619 ? 1490 ALA A O    1 
ATOM   453  C  CB   . ALA A 1 31  ? -23.94745 -34.21856 -16.02851 1.000 12.86998 ? 1490 ALA A CB   1 
ATOM   454  H  H    . ALA A 1 31  ? -22.80547 -33.36536 -14.03418 1.000 14.65089 ? 1490 ALA A H    1 
ATOM   455  H  HA   . ALA A 1 31  ? -21.94104 -34.10973 -16.36846 1.000 14.61299 ? 1490 ALA A HA   1 
ATOM   456  H  HB1  . ALA A 1 31  ? -24.18244 -34.41259 -16.94939 1.000 15.44678 ? 1490 ALA A HB1  1 
ATOM   457  H  HB2  . ALA A 1 31  ? -23.87589 -35.04418 -15.52439 1.000 15.44678 ? 1490 ALA A HB2  1 
ATOM   458  H  HB3  . ALA A 1 31  ? -24.61987 -33.64455 -15.62944 1.000 15.44678 ? 1490 ALA A HB3  1 
ATOM   459  N  N    . ALA A 1 32  ? -23.21593 -31.16562 -16.34877 1.000 11.49087 ? 1491 ALA A N    1 
ATOM   460  C  CA   . ALA A 1 32  ? -23.24657 -29.90931 -17.07396 1.000 11.45666 ? 1491 ALA A CA   1 
ATOM   461  C  C    . ALA A 1 32  ? -21.83723 -29.40190 -17.34305 1.000 10.89870 ? 1491 ALA A C    1 
ATOM   462  O  O    . ALA A 1 32  ? -21.55452 -28.90795 -18.43488 1.000 11.60404 ? 1491 ALA A O    1 
ATOM   463  C  CB   . ALA A 1 32  ? -24.02251 -28.90519 -16.23029 1.000 12.11989 ? 1491 ALA A CB   1 
ATOM   464  H  H    . ALA A 1 32  ? -23.59935 -31.13979 -15.57940 1.000 13.79184 ? 1491 ALA A H    1 
ATOM   465  H  HA   . ALA A 1 32  ? -23.68531 -30.02257 -17.93162 1.000 13.75078 ? 1491 ALA A HA   1 
ATOM   466  H  HB1  . ALA A 1 32  ? -24.03811 -28.05140 -16.69040 1.000 14.54667 ? 1491 ALA A HB1  1 
ATOM   467  H  HB2  . ALA A 1 32  ? -24.92785 -29.23032 -16.10557 1.000 14.54667 ? 1491 ALA A HB2  1 
ATOM   468  H  HB3  . ALA A 1 32  ? -23.58398 -28.80957 -15.37037 1.000 14.54667 ? 1491 ALA A HB3  1 
ATOM   469  N  N    . ALA A 1 33  ? -20.94435 -29.52446 -16.35392 1.000 11.16452 ? 1492 ALA A N    1 
ATOM   470  C  CA   . ALA A 1 33  ? -19.55201 -29.12060 -16.54823 1.000 10.83027 ? 1492 ALA A CA   1 
ATOM   471  C  C    . ALA A 1 33  ? -18.93425 -29.88271 -17.71137 1.000 10.73815 ? 1492 ALA A C    1 
ATOM   472  O  O    . ALA A 1 33  ? -18.35136 -29.28650 -18.62404 1.000 11.25926 ? 1492 ALA A O    1 
ATOM   473  C  CB   . ALA A 1 33  ? -18.75598 -29.35275 -15.26369 1.000 10.99607 ? 1492 ALA A CB   1 
ATOM   474  H  H    . ALA A 1 33  ? -21.11867 -29.83488 -15.57108 1.000 13.40022 ? 1492 ALA A H    1 
ATOM   475  H  HA   . ALA A 1 33  ? -19.51900 -28.17253 -16.75065 1.000 12.99912 ? 1492 ALA A HA   1 
ATOM   476  H  HB1  . ALA A 1 33  ? -17.83447 -29.08815 -15.41105 1.000 13.19809 ? 1492 ALA A HB1  1 
ATOM   477  H  HB2  . ALA A 1 33  ? -19.14324 -28.82004 -14.55154 1.000 13.19809 ? 1492 ALA A HB2  1 
ATOM   478  H  HB3  . ALA A 1 33  ? -18.79695 -30.29390 -15.03250 1.000 13.19809 ? 1492 ALA A HB3  1 
ATOM   479  N  N    . LEU A 1 34  ? -19.03151 -31.21494 -17.69427 1.000 11.20136 ? 1493 LEU A N    1 
ATOM   480  C  CA   . LEU A 1 34  ? -18.39122 -32.00933 -18.73697 1.000 12.27518 ? 1493 LEU A CA   1 
ATOM   481  C  C    . LEU A 1 34  ? -18.94350 -31.63698 -20.10355 1.000 12.46467 ? 1493 LEU A C    1 
ATOM   482  O  O    . LEU A 1 34  ? -18.19867 -31.52315 -21.08580 1.000 12.29360 ? 1493 LEU A O    1 
ATOM   483  C  CB   . LEU A 1 34  ? -18.62884 -33.49799 -18.45734 1.000 13.01737 ? 1493 LEU A CB   1 
ATOM   484  C  CG   . LEU A 1 34  ? -17.83687 -34.05198 -17.27694 1.000 13.35425 ? 1493 LEU A CG   1 
ATOM   485  C  CD1  . LEU A 1 34  ? -18.34459 -35.47342 -16.92773 1.000 13.44900 ? 1493 LEU A CD1  1 
ATOM   486  C  CD2  . LEU A 1 34  ? -16.33793 -34.09062 -17.54718 1.000 13.31741 ? 1493 LEU A CD2  1 
ATOM   487  H  H    . LEU A 1 34  ? -19.45440 -31.67195 -17.10105 1.000 13.44443 ? 1493 LEU A H    1 
ATOM   488  H  HA   . LEU A 1 34  ? -17.43559 -31.84301 -18.73455 1.000 14.73301 ? 1493 LEU A HA   1 
ATOM   489  H  HB2  . LEU A 1 34  ? -19.57084 -33.62976 -18.26716 1.000 15.62364 ? 1493 LEU A HB2  1 
ATOM   490  H  HB3  . LEU A 1 34  ? -18.37541 -34.00425 -19.24497 1.000 15.62364 ? 1493 LEU A HB3  1 
ATOM   491  H  HG   . LEU A 1 34  ? -17.97249 -33.45880 -16.52153 1.000 16.02790 ? 1493 LEU A HG   1 
ATOM   492  H  HD11 . LEU A 1 34  ? -17.81923 -35.82445 -16.19174 1.000 16.14160 ? 1493 LEU A HD11 1 
ATOM   493  H  HD12 . LEU A 1 34  ? -19.27878 -35.42108 -16.67188 1.000 16.14160 ? 1493 LEU A HD12 1 
ATOM   494  H  HD13 . LEU A 1 34  ? -18.24624 -36.04395 -17.70601 1.000 16.14160 ? 1493 LEU A HD13 1 
ATOM   495  H  HD21 . LEU A 1 34  ? -15.89858 -34.56344 -16.82309 1.000 15.98368 ? 1493 LEU A HD21 1 
ATOM   496  H  HD22 . LEU A 1 34  ? -16.18011 -34.55064 -18.38645 1.000 15.98368 ? 1493 LEU A HD22 1 
ATOM   497  H  HD23 . LEU A 1 34  ? -16.00304 -33.18180 -17.60005 1.000 15.98368 ? 1493 LEU A HD23 1 
ATOM   498  N  N    . ALA A 1 35  ? -20.26430 -31.43468 -20.18566 1.000 12.41730 ? 1494 ALA A N    1 
ATOM   499  C  CA   . ALA A 1 35  ? -20.88266 -31.07436 -21.45214 1.000 12.88578 ? 1494 ALA A CA   1 
ATOM   500  C  C    . ALA A 1 35  ? -20.42077 -29.70933 -21.93777 1.000 12.86999 ? 1494 ALA A C    1 
ATOM   501  O  O    . ALA A 1 35  ? -20.47846 -29.44037 -23.14533 1.000 14.80969 ? 1494 ALA A O    1 
ATOM   502  C  CB   . ALA A 1 35  ? -22.39963 -31.07046 -21.29539 1.000 13.23055 ? 1494 ALA A CB   1 
ATOM   503  H  H    . ALA A 1 35  ? -20.81292 -31.50056 -19.52666 1.000 14.90356 ? 1494 ALA A H    1 
ATOM   504  H  HA   . ALA A 1 35  ? -20.64408 -31.73350 -22.12260 1.000 15.46573 ? 1494 ALA A HA   1 
ATOM   505  H  HB1  . ALA A 1 35  ? -22.80395 -30.82371 -22.14188 1.000 15.87946 ? 1494 ALA A HB1  1 
ATOM   506  H  HB2  . ALA A 1 35  ? -22.69250 -31.95782 -21.03513 1.000 15.87946 ? 1494 ALA A HB2  1 
ATOM   507  H  HB3  . ALA A 1 35  ? -22.64483 -30.42745 -20.61179 1.000 15.87946 ? 1494 ALA A HB3  1 
ATOM   508  N  N    . GLY A 1 36  ? -19.95619 -28.86666 -21.02828 1.000 12.21464 ? 1495 GLY A N    1 
ATOM   509  C  CA   . GLY A 1 36  ? -19.36149 -27.58607 -21.32148 1.000 11.74353 ? 1495 GLY A CA   1 
ATOM   510  C  C    . GLY A 1 36  ? -17.86316 -27.61670 -21.49097 1.000 11.80407 ? 1495 GLY A C    1 
ATOM   511  O  O    . GLY A 1 36  ? -17.24343 -26.54876 -21.60654 1.000 12.31465 ? 1495 GLY A O    1 
ATOM   512  H  H    . GLY A 1 36  ? -19.97835 -29.02980 -20.18418 1.000 14.66037 ? 1495 GLY A H    1 
ATOM   513  H  HA2  . GLY A 1 36  ? -19.74688 -27.24391 -22.14324 1.000 14.09504 ? 1495 GLY A HA2  1 
ATOM   514  H  HA3  . GLY A 1 36  ? -19.56651 -26.97379 -20.59762 1.000 14.09504 ? 1495 GLY A HA3  1 
ATOM   515  N  N    . GLY A 1 37  ? -17.25695 -28.80130 -21.53065 1.000 12.11726 ? 1496 GLY A N    1 
ATOM   516  C  CA   . GLY A 1 37  ? -15.82553 -28.89858 -21.72302 1.000 12.39887 ? 1496 GLY A CA   1 
ATOM   517  C  C    . GLY A 1 37  ? -14.99990 -28.61398 -20.49456 1.000 11.82249 ? 1496 GLY A C    1 
ATOM   518  O  O    . GLY A 1 37  ? -13.78748 -28.37209 -20.61294 1.000 12.60153 ? 1496 GLY A O    1 
ATOM   519  H  H    . GLY A 1 37  ? -17.65658 -29.55835 -21.44827 1.000 14.54351 ? 1496 GLY A H    1 
ATOM   520  H  HA2  . GLY A 1 37  ? -15.61256 -29.79682 -22.02088 1.000 14.88144 ? 1496 GLY A HA2  1 
ATOM   521  H  HA3  . GLY A 1 37  ? -15.56089 -28.26700 -22.41002 1.000 14.88144 ? 1496 GLY A HA3  1 
ATOM   522  N  N    . ILE A 1 38  ? -15.61835 -28.66208 -19.31931 1.000 11.06451 ? 1497 ILE A N    1 
ATOM   523  C  CA   . ILE A 1 38  ? -14.99102 -28.37409 -18.04127 1.000 11.14083 ? 1497 ILE A CA   1 
ATOM   524  C  C    . ILE A 1 38  ? -14.74766 -29.68034 -17.31102 1.000 11.06187 ? 1497 ILE A C    1 
ATOM   525  O  O    . ILE A 1 38  ? -15.68104 -30.46891 -17.10437 1.000 11.78301 ? 1497 ILE A O    1 
ATOM   526  C  CB   . ILE A 1 38  ? -15.88747 -27.44240 -17.20637 1.000 11.89618 ? 1497 ILE A CB   1 
ATOM   527  C  CG1  . ILE A 1 38  ? -16.22962 -26.14364 -17.92648 1.000 14.12013 ? 1497 ILE A CG1  1 
ATOM   528  C  CG2  . ILE A 1 38  ? -15.25222 -27.14796 -15.88303 1.000 11.35665 ? 1497 ILE A CG2  1 
ATOM   529  C  CD1  . ILE A 1 38  ? -15.16480 -25.47289 -18.61060 1.000 16.47831 ? 1497 ILE A CD1  1 
ATOM   530  H  H    . ILE A 1 38  ? -16.44830 -28.87120 -19.23528 1.000 13.28020 ? 1497 ILE A H    1 
ATOM   531  H  HA   . ILE A 1 38  ? -14.13047 -27.95183 -18.18975 1.000 13.37179 ? 1497 ILE A HA   1 
ATOM   532  H  HB   . ILE A 1 38  ? -16.72173 -27.91781 -17.06894 1.000 14.27822 ? 1497 ILE A HB   1 
ATOM   533  H  HG12 . ILE A 1 38  ? -16.90964 -26.34049 -18.58959 1.000 16.94696 ? 1497 ILE A HG12 1 
ATOM   534  H  HG13 . ILE A 1 38  ? -16.57759 -25.52091 -17.26919 1.000 16.94696 ? 1497 ILE A HG13 1 
ATOM   535  H  HG21 . ILE A 1 38  ? -15.84218 -26.57348 -15.37037 1.000 13.63077 ? 1497 ILE A HG21 1 
ATOM   536  H  HG22 . ILE A 1 38  ? -15.10868 -27.98202 -15.40908 1.000 13.63077 ? 1497 ILE A HG22 1 
ATOM   537  H  HG23 . ILE A 1 38  ? -14.40381 -26.70204 -16.03224 1.000 13.63077 ? 1497 ILE A HG23 1 
ATOM   538  H  HD11 . ILE A 1 38  ? -15.51388 -24.66973 -19.02770 1.000 19.77677 ? 1497 ILE A HD11 1 
ATOM   539  H  HD12 . ILE A 1 38  ? -14.47506 -25.23974 -17.96966 1.000 19.77677 ? 1497 ILE A HD12 1 
ATOM   540  H  HD13 . ILE A 1 38  ? -14.80116 -26.06557 -19.28692 1.000 19.77677 ? 1497 ILE A HD13 1 
ATOM   541  N  N    . THR A 1 39  ? -13.49248 -29.93405 -16.94206 1.000 11.05661 ? 1498 THR A N    1 
ATOM   542  C  CA   . THR A 1 39  ? -13.11937 -31.17386 -16.29374 1.000 10.48023 ? 1498 THR A CA   1 
ATOM   543  C  C    . THR A 1 39  ? -12.79064 -31.02049 -14.82042 1.000 10.59603 ? 1498 THR A C    1 
ATOM   544  O  O    . THR A 1 39  ? -12.55912 -32.03120 -14.13663 1.000 10.91185 ? 1498 THR A O    1 
ATOM   545  C  CB   . THR A 1 39  ? -11.93752 -31.82764 -17.01532 1.000 11.19873 ? 1498 THR A CB   1 
ATOM   546  O  OG1  . THR A 1 39  ? -10.85076 -30.88619 -17.10130 1.000 11.63036 ? 1498 THR A OG1  1 
ATOM   547  C  CG2  . THR A 1 39  ? -12.34120 -32.22490 -18.41718 1.000 11.91724 ? 1498 THR A CG2  1 
ATOM   548  H  H    . THR A 1 39  ? -12.83559 -29.39193 -17.06118 1.000 13.27073 ? 1498 THR A H    1 
ATOM   549  H  HA   . THR A 1 39  ? -13.87046 -31.78423 -16.35861 1.000 12.57907 ? 1498 THR A HA   1 
ATOM   550  H  HB   . THR A 1 39  ? -11.65449 -32.61775 -16.52897 1.000 13.44128 ? 1498 THR A HB   1 
ATOM   551  H  HG1  . THR A 1 39  ? -10.60326 -30.66194 -16.33055 1.000 13.95923 ? 1498 THR A HG1  1 
ATOM   552  H  HG21 . THR A 1 39  ? -11.59494 -32.64794 -18.87000 1.000 14.30348 ? 1498 THR A HG21 1 
ATOM   553  H  HG22 . THR A 1 39  ? -13.08383 -32.84806 -18.38455 1.000 14.30348 ? 1498 THR A HG22 1 
ATOM   554  H  HG23 . THR A 1 39  ? -12.61055 -31.44022 -18.91979 1.000 14.30348 ? 1498 THR A HG23 1 
ATOM   555  N  N    . MET A 1 40  ? -12.73613 -29.80270 -14.31759 1.000 9.88805  ? 1499 MET A N    1 
ATOM   556  C  CA   . MET A 1 40  ? -12.49023 -29.51401 -12.92324 1.000 9.81962  ? 1499 MET A CA   1 
ATOM   557  C  C    . MET A 1 40  ? -13.26907 -28.28999 -12.50112 1.000 9.79067  ? 1499 MET A C    1 
ATOM   558  O  O    . MET A 1 40  ? -13.24657 -27.27120 -13.19951 1.000 10.42758 ? 1499 MET A O    1 
ATOM   559  C  CB   . MET A 1 40  ? -11.00575 -29.20854 -12.65650 1.000 10.18019 ? 1499 MET A CB   1 
ATOM   560  C  CG   . MET A 1 40  ? -10.60247 -29.30714 -11.20768 1.000 10.98028 ? 1499 MET A CG   1 
ATOM   561  S  SD   . MET A 1 40  ? -8.91040  -28.70359 -10.89331 1.000 11.29874 ? 1499 MET A SD   1 
ATOM   562  C  CE   . MET A 1 40  ? -7.96379  -29.82900 -11.87126 1.000 11.60931 ? 1499 MET A CE   1 
ATOM   563  H  H    . MET A 1 40  ? -12.84399 -29.09120 -14.78849 1.000 11.86846 ? 1499 MET A H    1 
ATOM   564  H  HA   . MET A 1 40  ? -12.77195 -30.29472 -12.42122 1.000 11.78634 ? 1499 MET A HA   1 
ATOM   565  H  HB2  . MET A 1 40  ? -10.46505 -29.84055 -13.15560 1.000 12.21902 ? 1499 MET A HB2  1 
ATOM   566  H  HB3  . MET A 1 40  ? -10.81760 -28.30431 -12.95291 1.000 12.21902 ? 1499 MET A HB3  1 
ATOM   567  H  HG2  . MET A 1 40  ? -11.21318 -28.77501 -10.67405 1.000 13.17914 ? 1499 MET A HG2  1 
ATOM   568  H  HG3  . MET A 1 40  ? -10.64407 -30.23618 -10.93191 1.000 13.17914 ? 1499 MET A HG3  1 
ATOM   569  H  HE1  . MET A 1 40  ? -7.02460  -29.59748 -11.79890 1.000 13.93396 ? 1499 MET A HE1  1 
ATOM   570  H  HE2  . MET A 1 40  ? -8.10839  -30.73060 -11.54399 1.000 13.93396 ? 1499 MET A HE2  1 
ATOM   571  H  HE3  . MET A 1 40  ? -8.25056  -29.76263 -12.79552 1.000 13.93396 ? 1499 MET A HE3  1 
ATOM   572  N  N    . VAL A 1 41  ? -13.93239 -28.37538 -11.35914 1.000 9.90647  ? 1500 VAL A N    1 
ATOM   573  C  CA   . VAL A 1 41  ? -14.73334 -27.26474 -10.85134 1.000 10.25651 ? 1500 VAL A CA   1 
ATOM   574  C  C    . VAL A 1 41  ? -14.37538 -26.97961 -9.40451  1.000 10.27494 ? 1500 VAL A C    1 
ATOM   575  O  O    . VAL A 1 41  ? -14.04890 -27.88599 -8.63745  1.000 10.89343 ? 1500 VAL A O    1 
ATOM   576  C  CB   . VAL A 1 41  ? -16.25542 -27.52501 -10.95807 1.000 11.14083 ? 1500 VAL A CB   1 
ATOM   577  C  CG1  . VAL A 1 41  ? -16.68906 -27.66148 -12.40130 1.000 11.55140 ? 1500 VAL A CG1  1 
ATOM   578  C  CG2  . VAL A 1 41  ? -16.68652 -28.76667 -10.13041 1.000 11.71458 ? 1500 VAL A CG2  1 
ATOM   579  H  H    . VAL A 1 41  ? -13.93634 -29.07099 -10.85345 1.000 11.89056 ? 1500 VAL A H    1 
ATOM   580  H  HA   . VAL A 1 41  ? -14.50857 -26.48562 -11.38365 1.000 12.31061 ? 1500 VAL A HA   1 
ATOM   581  H  HB   . VAL A 1 41  ? -16.71062 -26.75523 -10.58240 1.000 13.37179 ? 1500 VAL A HB   1 
ATOM   582  H  HG11 . VAL A 1 41  ? -17.64564 -27.81970 -12.43002 1.000 13.86448 ? 1500 VAL A HG11 1 
ATOM   583  H  HG12 . VAL A 1 41  ? -16.47498 -26.84208 -12.87421 1.000 13.86448 ? 1500 VAL A HG12 1 
ATOM   584  H  HG13 . VAL A 1 41  ? -16.21809 -28.40812 -12.80332 1.000 13.86448 ? 1500 VAL A HG13 1 
ATOM   585  H  HG21 . VAL A 1 41  ? -17.62041 -28.95740 -10.31032 1.000 14.06029 ? 1500 VAL A HG21 1 
ATOM   586  H  HG22 . VAL A 1 41  ? -16.13847 -29.52418 -10.38872 1.000 14.06029 ? 1500 VAL A HG22 1 
ATOM   587  H  HG23 . VAL A 1 41  ? -16.56362 -28.57577 -9.18735  1.000 14.06029 ? 1500 VAL A HG23 1 
ATOM   588  N  N    . CYS A 1 42  ? -14.48969 -25.70893 -9.00810  1.000 10.07754 ? 1501 CYS A N    1 
ATOM   589  C  CA   . CYS A 1 42  ? -14.33706 -25.30329 -7.61712  1.000 9.61960  ? 1501 CYS A CA   1 
ATOM   590  C  C    . CYS A 1 42  ? -15.70386 -24.82724 -7.12403  1.000 9.46695  ? 1501 CYS A C    1 
ATOM   591  O  O    . CYS A 1 42  ? -16.25696 -23.83655 -7.64456  1.000 9.34851  ? 1501 CYS A O    1 
ATOM   592  C  CB   . CYS A 1 42  ? -13.27996 -24.21248 -7.44782  1.000 10.47496 ? 1501 CYS A CB   1 
ATOM   593  S  SG   . CYS A 1 42  ? -11.63527 -24.72467 -7.92289  1.000 11.40928 ? 1501 CYS A SG   1 
ATOM   594  H  H    . CYS A 1 42  ? -14.65867 -25.05510 -9.54060  1.000 12.09585 ? 1501 CYS A H    1 
ATOM   595  H  HA   . CYS A 1 42  ? -14.04688 -26.06017 -7.08436  1.000 11.54631 ? 1501 CYS A HA   1 
ATOM   596  H  HB2  . CYS A 1 42  ? -13.52464 -23.45293 -7.99929  1.000 12.57275 ? 1501 CYS A HB2  1 
ATOM   597  H  HB3  . CYS A 1 42  ? -13.25036 -23.94915 -6.51472  1.000 12.57275 ? 1501 CYS A HB3  1 
ATOM   598  H  HG   . CYS A 1 42  ? -10.87880 -23.80699 -7.76287  1.000 13.69393 ? 1501 CYS A HG   1 
ATOM   599  N  N    . ALA A 1 43  ? -16.23699 -25.52372 -6.13571  1.000 10.15650 ? 1502 ALA A N    1 
ATOM   600  C  CA   . ALA A 1 43  ? -17.61756 -25.35903 -5.71004  1.000 10.16703 ? 1502 ALA A CA   1 
ATOM   601  C  C    . ALA A 1 43  ? -17.74302 -24.43576 -4.50616  1.000 9.79593  ? 1502 ALA A C    1 
ATOM   602  O  O    . ALA A 1 43  ? -17.04935 -24.60486 -3.49886  1.000 10.35126 ? 1502 ALA A O    1 
ATOM   603  C  CB   . ALA A 1 43  ? -18.22711 -26.72472 -5.39191  1.000 11.43034 ? 1502 ALA A CB   1 
ATOM   604  H  H    . ALA A 1 43  ? -15.80781 -26.11522 -5.68234  1.000 12.19060 ? 1502 ALA A H    1 
ATOM   605  H  HA   . ALA A 1 43  ? -18.11060 -24.93397 -6.42916  1.000 12.20323 ? 1502 ALA A HA   1 
ATOM   606  H  HB1  . ALA A 1 43  ? -19.15210 -26.60354 -5.12618  1.000 13.71920 ? 1502 ALA A HB1  1 
ATOM   607  H  HB2  . ALA A 1 43  ? -18.18084 -27.28335 -6.18355  1.000 13.71920 ? 1502 ALA A HB2  1 
ATOM   608  H  HB3  . ALA A 1 43  ? -17.72608 -27.13349 -4.66888  1.000 13.71920 ? 1502 ALA A HB3  1 
ATOM   609  N  N    . MET A 1 44  ? -18.64526 -23.46053 -4.62524  1.000 9.35114  ? 1503 MET A N    1 
ATOM   610  C  CA   . MET A 1 44  ? -18.80562 -22.48835 -3.58446  1.000 9.18533  ? 1503 MET A CA   1 
ATOM   611  C  C    . MET A 1 44  ? -19.53269 -23.00755 -2.34178  1.000 9.96174  ? 1503 MET A C    1 
ATOM   612  O  O    . MET A 1 44  ? -20.23188 -24.02096 -2.39676  1.000 10.96449 ? 1503 MET A O    1 
ATOM   613  C  CB   . MET A 1 44  ? -19.44351 -21.20973 -4.07201  1.000 9.97227  ? 1503 MET A CB   1 
ATOM   614  C  CG   . MET A 1 44  ? -18.62064 -20.50615 -5.15057  1.000 10.74868 ? 1503 MET A CG   1 
ATOM   615  S  SD   . MET A 1 44  ? -17.24771 -19.75841 -4.18803  1.000 11.06714 ? 1503 MET A SD   1 
ATOM   616  C  CE   . MET A 1 44  ? -16.21704 -19.21410 -5.52766  1.000 11.43823 ? 1503 MET A CE   1 
ATOM   617  H  H    . MET A 1 44  ? -19.16678 -23.35306 -5.30056  1.000 11.22417 ? 1503 MET A H    1 
ATOM   618  H  HA   . MET A 1 44  ? -17.90118 -22.27185 -3.30876  1.000 11.02520 ? 1503 MET A HA   1 
ATOM   619  H  HB2  . MET A 1 44  ? -20.31450 -21.41522 -4.44624  1.000 11.96952 ? 1503 MET A HB2  1 
ATOM   620  H  HB3  . MET A 1 44  ? -19.53945 -20.60041 -3.32340  1.000 11.96952 ? 1503 MET A HB3  1 
ATOM   621  H  HG2  . MET A 1 44  ? -18.27652 -21.13790 -5.80124  1.000 12.90121 ? 1503 MET A HG2  1 
ATOM   622  H  HG3  . MET A 1 44  ? -19.13805 -19.81816 -5.59762  1.000 12.90121 ? 1503 MET A HG3  1 
ATOM   623  H  HE1  . MET A 1 44  ? -15.48735 -18.68464 -5.16973  1.000 13.72868 ? 1503 MET A HE1  1 
ATOM   624  H  HE2  . MET A 1 44  ? -15.86600 -19.99029 -5.99155  1.000 13.72868 ? 1503 MET A HE2  1 
ATOM   625  H  HE3  . MET A 1 44  ? -16.74788 -18.67697 -6.13643  1.000 13.72868 ? 1503 MET A HE3  1 
ATOM   626  N  N    . PRO A 1 45  ? -19.35381 -22.33329 -1.20161  1.000 9.81699  ? 1504 PRO A N    1 
ATOM   627  C  CA   . PRO A 1 45  ? -19.75312 -22.89055 0.10553   1.000 10.46443 ? 1504 PRO A CA   1 
ATOM   628  C  C    . PRO A 1 45  ? -21.12415 -22.46235 0.61361   1.000 11.18820 ? 1504 PRO A C    1 
ATOM   629  O  O    . PRO A 1 45  ? -21.47246 -22.83569 1.74458   1.000 11.57246 ? 1504 PRO A O    1 
ATOM   630  C  CB   . PRO A 1 45  ? -18.65369 -22.35331 1.02820   1.000 11.19347 ? 1504 PRO A CB   1 
ATOM   631  C  CG   . PRO A 1 45  ? -18.39944 -20.95162 0.44785   1.000 10.83553 ? 1504 PRO A CG   1 
ATOM   632  C  CD   . PRO A 1 45  ? -18.54803 -21.09207 -1.05076  1.000 10.35652 ? 1504 PRO A CD   1 
ATOM   633  H  HA   . PRO A 1 45  ? -19.71493 -23.85949 0.08124   1.000 12.56012 ? 1504 PRO A HA   1 
ATOM   634  H  HB2  . PRO A 1 45  ? -18.96844 -22.30893 1.94464   1.000 13.43496 ? 1504 PRO A HB2  1 
ATOM   635  H  HB3  . PRO A 1 45  ? -17.86155 -22.91071 0.97611   1.000 13.43496 ? 1504 PRO A HB3  1 
ATOM   636  H  HG2  . PRO A 1 45  ? -19.05296 -20.32781 0.80094   1.000 13.00543 ? 1504 PRO A HG2  1 
ATOM   637  H  HG3  . PRO A 1 45  ? -17.50366 -20.65955 0.67842   1.000 13.00543 ? 1504 PRO A HG3  1 
ATOM   638  H  HD2  . PRO A 1 45  ? -19.01659 -20.32913 -1.42395  1.000 12.43063 ? 1504 PRO A HD2  1 
ATOM   639  H  HD3  . PRO A 1 45  ? -17.68152 -21.18955 -1.47568  1.000 12.43063 ? 1504 PRO A HD3  1 
ATOM   640  N  N    . ASN A 1 46  ? -21.92056 -21.77459 -0.18996  1.000 11.40402 ? 1505 ASN A N    1 
ATOM   641  C  CA   . ASN A 1 46  ? -23.21135 -21.25432 0.26186   1.000 12.00936 ? 1505 ASN A CA   1 
ATOM   642  C  C    . ASN A 1 46  ? -24.33357 -22.27092 0.09492   1.000 12.86735 ? 1505 ASN A C    1 
ATOM   643  O  O    . ASN A 1 46  ? -25.42338 -21.97033 -0.39411  1.000 13.24371 ? 1505 ASN A O    1 
ATOM   644  C  CB   . ASN A 1 46  ? -23.54501 -19.95305 -0.44716  1.000 12.42519 ? 1505 ASN A CB   1 
ATOM   645  C  CG   . ASN A 1 46  ? -23.76428 -20.11810 -1.94185  1.000 12.95157 ? 1505 ASN A CG   1 
ATOM   646  O  OD1  . ASN A 1 46  ? -23.30287 -21.06573 -2.58489  1.000 12.39624 ? 1505 ASN A OD1  1 
ATOM   647  N  ND2  . ASN A 1 46  ? -24.49952 -19.18607 -2.49917  1.000 14.36490 ? 1505 ASN A ND2  1 
ATOM   648  H  H    . ASN A 1 46  ? -21.73812 -21.59179 -1.01027  1.000 13.68762 ? 1505 ASN A H    1 
ATOM   649  H  HA   . ASN A 1 46  ? -23.13113 -21.05910 1.20862   1.000 14.41402 ? 1505 ASN A HA   1 
ATOM   650  H  HB2  . ASN A 1 46  ? -24.35895 -19.58816 -0.06605  1.000 14.91303 ? 1505 ASN A HB2  1 
ATOM   651  H  HB3  . ASN A 1 46  ? -22.81174 -19.33061 -0.32146  1.000 14.91303 ? 1505 ASN A HB3  1 
ATOM   652  H  HD21 . ASN A 1 46  ? -24.66493 -19.21584 -3.34258  1.000 17.24067 ? 1505 ASN A HD21 1 
ATOM   653  H  HD22 . ASN A 1 46  ? -24.81627 -18.54511 -2.02122  1.000 17.24067 ? 1505 ASN A HD22 1 
ATOM   654  N  N    . THR A 1 47  ? -24.05333 -23.48713 0.52730   1.000 13.31214 ? 1506 THR A N    1 
ATOM   655  C  CA   . THR A 1 47  ? -25.00246 -24.58675 0.52223   1.000 14.04118 ? 1506 THR A CA   1 
ATOM   656  C  C    . THR A 1 47  ? -25.79629 -24.59714 1.83320   1.000 14.92549 ? 1506 THR A C    1 
ATOM   657  O  O    . THR A 1 47  ? -25.67157 -23.68813 2.66214   1.000 14.92813 ? 1506 THR A O    1 
ATOM   658  C  CB   . THR A 1 47  ? -24.24774 -25.90486 0.31978   1.000 13.95433 ? 1506 THR A CB   1 
ATOM   659  O  OG1  . THR A 1 47  ? -23.15327 -26.00465 1.24720   1.000 14.29121 ? 1506 THR A OG1  1 
ATOM   660  C  CG2  . THR A 1 47  ? -23.70170 -25.99692 -1.09055  1.000 14.55440 ? 1506 THR A CG2  1 
ATOM   661  H  H    . THR A 1 47  ? -23.28571 -23.71223 0.84304   1.000 15.97737 ? 1506 THR A H    1 
ATOM   662  H  HA   . THR A 1 47  ? -25.62391 -24.45264 -0.21037  1.000 16.85221 ? 1506 THR A HA   1 
ATOM   663  H  HB   . THR A 1 47  ? -24.86263 -26.64011 0.46883   1.000 16.74799 ? 1506 THR A HB   1 
ATOM   664  H  HG1  . THR A 1 47  ? -23.44129 -25.97531 2.03573   1.000 17.15225 ? 1506 THR A HG1  1 
ATOM   665  H  HG21 . THR A 1 47  ? -23.22626 -26.83418 -1.20824  1.000 17.46807 ? 1506 THR A HG21 1 
ATOM   666  H  HG22 . THR A 1 47  ? -24.42882 -25.95505 -1.73122  1.000 17.46807 ? 1506 THR A HG22 1 
ATOM   667  H  HG23 . THR A 1 47  ? -23.09134 -25.26199 -1.25863  1.000 17.46807 ? 1506 THR A HG23 1 
ATOM   668  N  N    . ARG A 1 48  ? -26.61777 -25.63156 2.04186   1.000 16.34145 ? 1507 ARG A N    1 
ATOM   669  C  CA   . ARG A 1 48  ? -27.39584 -25.79886 3.26973   1.000 18.72595 ? 1507 ARG A CA   1 
ATOM   670  C  C    . ARG A 1 48  ? -27.17566 -27.20786 3.80239   1.000 18.44434 ? 1507 ARG A C    1 
ATOM   671  O  O    . ARG A 1 48  ? -27.76122 -28.16696 3.27460   1.000 18.83386 ? 1507 ARG A O    1 
ATOM   672  C  CB   . ARG A 1 48  ? -28.88373 -25.57881 3.00014   1.000 20.80777 ? 1507 ARG A CB   1 
ATOM   673  H  H    . ARG A 1 48  ? -26.74262 -26.26331 1.47186   1.000 19.61254 ? 1507 ARG A H    1 
ATOM   674  H  HA   . ARG A 1 48  ? -27.08981 -25.15906 3.93146   1.000 22.47393 ? 1507 ARG A HA   1 
ATOM   675  N  N    . PRO A 1 49  ? -26.36932 -27.38726 4.84692   1.000 18.21536 ? 1508 PRO A N    1 
ATOM   676  C  CA   . PRO A 1 49  ? -25.63462 -26.38071 5.63063   1.000 17.95217 ? 1508 PRO A CA   1 
ATOM   677  C  C    . PRO A 1 49  ? -24.52195 -25.73320 4.80985   1.000 15.94404 ? 1508 PRO A C    1 
ATOM   678  O  O    . PRO A 1 49  ? -23.97214 -26.36569 3.90357   1.000 16.19670 ? 1508 PRO A O    1 
ATOM   679  C  CB   . PRO A 1 49  ? -25.06863 -27.20756 6.79619   1.000 19.44972 ? 1508 PRO A CB   1 
ATOM   680  C  CG   . PRO A 1 49  ? -24.80633 -28.54631 6.17701   1.000 19.78660 ? 1508 PRO A CG   1 
ATOM   681  C  CD   . PRO A 1 49  ? -25.98525 -28.76085 5.23679   1.000 19.21285 ? 1508 PRO A CD   1 
ATOM   682  H  HA   . PRO A 1 49  ? -26.23760 -25.70241 5.97302   1.000 21.54540 ? 1508 PRO A HA   1 
ATOM   683  H  HB2  . PRO A 1 49  ? -24.25051 -26.80553 7.12780   1.000 23.34246 ? 1508 PRO A HB2  1 
ATOM   684  H  HB3  . PRO A 1 49  ? -25.72072 -27.27104 7.51149   1.000 23.34246 ? 1508 PRO A HB3  1 
ATOM   685  H  HG2  . PRO A 1 49  ? -23.96824 -28.52969 5.68892   1.000 23.74672 ? 1508 PRO A HG2  1 
ATOM   686  H  HG3  . PRO A 1 49  ? -24.77710 -29.23128 6.86321   1.000 23.74672 ? 1508 PRO A HG3  1 
ATOM   687  H  HD2  . PRO A 1 49  ? -25.71736 -29.27716 4.46055   1.000 23.05822 ? 1508 PRO A HD2  1 
ATOM   688  H  HD3  . PRO A 1 49  ? -26.71515 -29.20568 5.69534   1.000 23.05822 ? 1508 PRO A HD3  1 
ATOM   689  N  N    . PRO A 1 50  ? -24.16552 -24.48970 5.13901   1.000 14.98340 ? 1509 PRO A N    1 
ATOM   690  C  CA   . PRO A 1 50  ? -23.04135 -23.83764 4.45563   1.000 14.22015 ? 1509 PRO A CA   1 
ATOM   691  C  C    . PRO A 1 50  ? -21.71630 -24.43218 4.91869   1.000 13.45690 ? 1509 PRO A C    1 
ATOM   692  O  O    . PRO A 1 50  ? -21.57100 -24.90421 6.04798   1.000 13.82010 ? 1509 PRO A O    1 
ATOM   693  C  CB   . PRO A 1 50  ? -23.17035 -22.36658 4.87516   1.000 14.98076 ? 1509 PRO A CB   1 
ATOM   694  C  CG   . PRO A 1 50  ? -23.86527 -22.42863 6.19628   1.000 15.77559 ? 1509 PRO A CG   1 
ATOM   695  C  CD   . PRO A 1 50  ? -24.82533 -23.59993 6.10940   1.000 15.55188 ? 1509 PRO A CD   1 
ATOM   696  H  HA   . PRO A 1 50  ? -23.12244 -23.90488 3.49137   1.000 17.06697 ? 1509 PRO A HA   1 
ATOM   697  H  HB2  . PRO A 1 50  ? -22.29161 -21.96455 4.95936   1.000 17.97971 ? 1509 PRO A HB2  1 
ATOM   698  H  HB3  . PRO A 1 50  ? -23.69765 -21.87809 4.22384   1.000 17.97971 ? 1509 PRO A HB3  1 
ATOM   699  H  HG2  . PRO A 1 50  ? -23.21429 -22.57033 6.90130   1.000 18.93351 ? 1509 PRO A HG2  1 
ATOM   700  H  HG3  . PRO A 1 50  ? -24.34702 -21.60106 6.35099   1.000 18.93351 ? 1509 PRO A HG3  1 
ATOM   701  H  HD2  . PRO A 1 50  ? -24.92074 -24.03541 6.97088   1.000 18.66506 ? 1509 PRO A HD2  1 
ATOM   702  H  HD3  . PRO A 1 50  ? -25.69334 -23.31412 5.78418   1.000 18.66506 ? 1509 PRO A HD3  1 
ATOM   703  N  N    . ILE A 1 51  ? -20.72438 -24.36436 4.03720   1.000 13.14633 ? 1510 ILE A N    1 
ATOM   704  C  CA   . ILE A 1 51  ? -19.43574 -25.03761 4.27785   1.000 12.88841 ? 1510 ILE A CA   1 
ATOM   705  C  C    . ILE A 1 51  ? -18.55404 -24.04086 5.01821   1.000 13.16213 ? 1510 ILE A C    1 
ATOM   706  O  O    . ILE A 1 51  ? -17.63621 -23.42752 4.46434   1.000 13.67798 ? 1510 ILE A O    1 
ATOM   707  C  CB   . ILE A 1 51  ? -18.81300 -25.57555 2.99142   1.000 13.06474 ? 1510 ILE A CB   1 
ATOM   708  C  CG1  . ILE A 1 51  ? -19.84230 -26.36769 2.16089   1.000 13.85694 ? 1510 ILE A CG1  1 
ATOM   709  C  CG2  . ILE A 1 51  ? -17.61486 -26.46431 3.31554   1.000 13.16476 ? 1510 ILE A CG2  1 
ATOM   710  C  CD1  . ILE A 1 51  ? -20.64190 -27.41255 2.91728   1.000 14.48597 ? 1510 ILE A CD1  1 
ATOM   711  H  H    . ILE A 1 51  ? -20.76495 -23.93770 3.29160   1.000 15.77840 ? 1510 ILE A H    1 
ATOM   712  H  HA   . ILE A 1 51  ? -19.58172 -25.78995 4.87247   1.000 15.46889 ? 1510 ILE A HA   1 
ATOM   713  H  HB   . ILE A 1 51  ? -18.51837 -24.81485 2.46660   1.000 15.68049 ? 1510 ILE A HB   1 
ATOM   714  H  HG12 . ILE A 1 51  ? -20.47693 -25.73840 1.78386   1.000 16.63113 ? 1510 ILE A HG12 1 
ATOM   715  H  HG13 . ILE A 1 51  ? -19.36916 -26.82782 1.45003   1.000 16.63113 ? 1510 ILE A HG13 1 
ATOM   716  H  HG21 . ILE A 1 51  ? -17.27999 -26.85516 2.49334   1.000 15.80050 ? 1510 ILE A HG21 1 
ATOM   717  H  HG22 . ILE A 1 51  ? -16.92411 -25.92425 3.73039   1.000 15.80050 ? 1510 ILE A HG22 1 
ATOM   718  H  HG23 . ILE A 1 51  ? -17.89692 -27.16508 3.92403   1.000 15.80050 ? 1510 ILE A HG23 1 
ATOM   719  H  HD11 . ILE A 1 51  ? -21.16955 -27.92514 2.28504   1.000 17.38596 ? 1510 ILE A HD11 1 
ATOM   720  H  HD12 . ILE A 1 51  ? -20.02944 -27.99861 3.38879   1.000 17.38596 ? 1510 ILE A HD12 1 
ATOM   721  H  HD13 . ILE A 1 51  ? -21.22587 -26.96615 3.55022   1.000 17.38596 ? 1510 ILE A HD13 1 
ATOM   722  N  N    . ILE A 1 52  ? -18.81927 -23.90399 6.31702   1.000 13.81483 ? 1511 ILE A N    1 
ATOM   723  C  CA   . ILE A 1 52  ? -18.20410 -22.88361 7.15662   1.000 15.13341 ? 1511 ILE A CA   1 
ATOM   724  C  C    . ILE A 1 52  ? -17.50887 -23.47691 8.37023   1.000 15.44398 ? 1511 ILE A C    1 
ATOM   725  O  O    . ILE A 1 52  ? -17.05349 -22.74045 9.24361   1.000 16.14406 ? 1511 ILE A O    1 
ATOM   726  C  CB   . ILE A 1 52  ? -19.21420 -21.80435 7.58395   1.000 16.55464 ? 1511 ILE A CB   1 
ATOM   727  C  CG1  . ILE A 1 52  ? -20.40152 -22.38988 8.35564   1.000 17.84690 ? 1511 ILE A CG1  1 
ATOM   728  C  CG2  . ILE A 1 52  ? -19.67131 -21.00201 6.37597   1.000 17.18629 ? 1511 ILE A CG2  1 
ATOM   729  C  CD1  . ILE A 1 52  ? -21.25969 -21.28708 8.95793   1.000 19.58131 ? 1511 ILE A CD1  1 
ATOM   730  H  H    . ILE A 1 52  ? -19.36967 -24.40732 6.74519   1.000 16.58060 ? 1511 ILE A H    1 
ATOM   731  H  HA   . ILE A 1 52  ? -17.52337 -22.44593 6.62188   1.000 18.16289 ? 1511 ILE A HA   1 
ATOM   732  H  HB   . ILE A 1 52  ? -18.75969 -21.20678 8.19814   1.000 19.86836 ? 1511 ILE A HB   1 
ATOM   733  H  HG12 . ILE A 1 52  ? -20.95199 -22.91268 7.75186   1.000 21.41907 ? 1511 ILE A HG12 1 
ATOM   734  H  HG13 . ILE A 1 52  ? -20.07289 -22.95131 9.07515   1.000 21.41907 ? 1511 ILE A HG13 1 
ATOM   735  H  HG21 . ILE A 1 52  ? -20.20358 -20.24999 6.67938   1.000 20.62635 ? 1511 ILE A HG21 1 
ATOM   736  H  HG22 . ILE A 1 52  ? -18.89152 -20.68285 5.89538   1.000 20.62635 ? 1511 ILE A HG22 1 
ATOM   737  H  HG23 . ILE A 1 52  ? -20.20365 -21.57326 5.80048   1.000 20.62635 ? 1511 ILE A HG23 1 
ATOM   738  H  HD11 . ILE A 1 52  ? -21.90403 -21.68411 9.56464   1.000 23.50037 ? 1511 ILE A HD11 1 
ATOM   739  H  HD12 . ILE A 1 52  ? -20.68778 -20.66980 9.44041   1.000 23.50037 ? 1511 ILE A HD12 1 
ATOM   740  H  HD13 . ILE A 1 52  ? -21.72157 -20.82071 8.24375   1.000 23.50037 ? 1511 ILE A HD13 1 
ATOM   741  N  N    A ASP A 1 53  ? -17.44493 -24.79778 8.46527   0.457 15.67822 ? 1512 ASP A N    1 
ATOM   742  N  N    B ASP A 1 53  ? -17.41130 -24.80112 8.43406   0.543 15.51241 ? 1512 ASP A N    1 
ATOM   743  C  CA   A ASP A 1 53  ? -16.71024 -25.44069 9.54614   0.457 16.45726 ? 1512 ASP A CA   1 
ATOM   744  C  CA   B ASP A 1 53  ? -16.82377 -25.49118 9.57352   0.543 16.41778 ? 1512 ASP A CA   1 
ATOM   745  C  C    A ASP A 1 53  ? -16.33337 -26.84710 9.10418   0.457 16.09142 ? 1512 ASP A C    1 
ATOM   746  C  C    B ASP A 1 53  ? -16.37200 -26.86952 9.10617   0.543 15.87298 ? 1512 ASP A C    1 
ATOM   747  O  O    A ASP A 1 53  ? -16.70426 -27.30412 8.01943   0.457 16.09142 ? 1512 ASP A O    1 
ATOM   748  O  O    B ASP A 1 53  ? -16.70645 -27.31923 8.00687   0.543 15.85192 ? 1512 ASP A O    1 
ATOM   749  C  CB   A ASP A 1 53  ? -17.47708 -25.39974 10.87205  0.457 17.44422 ? 1512 ASP A CB   1 
ATOM   750  C  CB   B ASP A 1 53  ? -17.81727 -25.56318 10.73742  0.543 17.90480 ? 1512 ASP A CB   1 
ATOM   751  C  CG   A ASP A 1 53  ? -18.73304 -26.25904 10.86894  0.457 18.10745 ? 1512 ASP A CG   1 
ATOM   752  C  CG   B ASP A 1 53  ? -19.17294 -26.07779 10.30767  0.543 18.84965 ? 1512 ASP A CG   1 
ATOM   753  O  OD1  A ASP A 1 53  ? -18.96301 -27.03244 9.91646   0.457 17.99955 ? 1512 ASP A OD1  1 
ATOM   754  O  OD1  B ASP A 1 53  ? -19.25715 -27.26493 9.95523   0.543 18.52856 ? 1512 ASP A OD1  1 
ATOM   755  O  OD2  A ASP A 1 53  ? -19.49928 -26.15835 11.84542  0.457 18.57330 ? 1512 ASP A OD2  1 
ATOM   756  O  OD2  B ASP A 1 53  ? -20.15080 -25.30472 10.29499  0.543 19.71817 ? 1512 ASP A OD2  1 
ATOM   757  H  H    A ASP A 1 53  ? -17.81864 -25.34402 7.91613   0.457 18.81666 ? 1512 ASP A H    1 
ATOM   758  H  H    B ASP A 1 53  ? -17.68451 -25.33283 7.81580   0.543 18.61769 ? 1512 ASP A H    1 
ATOM   759  H  HA   A ASP A 1 53  ? -15.88295 -24.95664 9.69508   0.457 19.75150 ? 1512 ASP A HA   1 
ATOM   760  H  HA   B ASP A 1 53  ? -16.03779 -25.01837 9.88909   0.543 19.70413 ? 1512 ASP A HA   1 
ATOM   761  H  HB2  A ASP A 1 53  ? -16.89762 -25.72246 11.57985  0.457 20.93586 ? 1512 ASP A HB2  1 
ATOM   762  H  HB2  B ASP A 1 53  ? -17.46859 -26.16252 11.41573  0.543 21.48855 ? 1512 ASP A HB2  1 
ATOM   763  H  HB3  A ASP A 1 53  ? -17.74323 -24.48460 11.05255  0.457 20.93586 ? 1512 ASP A HB3  1 
ATOM   764  H  HB3  B ASP A 1 53  ? -17.93597 -24.67498 11.10879  0.543 21.48855 ? 1512 ASP A HB3  1 
ATOM   765  N  N    . ALA A 1 54  ? -15.57196 -27.51808 9.94592   1.000 16.33882 ? 1513 ALA A N    1 
ATOM   766  C  CA   . ALA A 1 54  ? -15.00848 -28.80809 9.57363   1.000 16.20723 ? 1513 ALA A CA   1 
ATOM   767  C  C    . ALA A 1 54  ? -16.08630 -29.87038 9.38223   1.000 16.22302 ? 1513 ALA A C    1 
ATOM   768  O  O    . ALA A 1 54  ? -16.01723 -30.62535 8.40295   1.000 16.43883 ? 1513 ALA A O    1 
ATOM   769  C  CB   . ALA A 1 54  ? -13.95289 -29.23407 10.59874  1.000 16.54148 ? 1513 ALA A CB   1 
ATOM   770  H  H    A ALA A 1 54  ? -15.36500 -27.25206 10.73712  0.457 19.60938 ? 1513 ALA A H    1 
ATOM   771  H  H    B ALA A 1 54  ? -15.34287 -27.23736 10.72587  0.543 19.60938 ? 1513 ALA A H    1 
ATOM   772  H  HA   . ALA A 1 54  ? -14.56380 -28.70661 8.71756   1.000 19.45147 ? 1513 ALA A HA   1 
ATOM   773  H  HB1  . ALA A 1 54  ? -13.64975 -30.13058 10.38596  1.000 19.85257 ? 1513 ALA A HB1  1 
ATOM   774  H  HB2  . ALA A 1 54  ? -13.20723 -28.61488 10.56013  1.000 19.85257 ? 1513 ALA A HB2  1 
ATOM   775  H  HB3  . ALA A 1 54  ? -14.34884 -29.22021 11.48414  1.000 19.85257 ? 1513 ALA A HB3  1 
ATOM   776  N  N    . PRO A 1 55  ? -17.08538 -29.97811 10.25865  1.000 16.34935 ? 1514 PRO A N    1 
ATOM   777  C  CA   . PRO A 1 55  ? -18.13362 -30.98288 10.00432  1.000 16.49673 ? 1514 PRO A CA   1 
ATOM   778  C  C    . PRO A 1 55  ? -18.84520 -30.78705 8.67798   1.000 15.58610 ? 1514 PRO A C    1 
ATOM   779  O  O    . PRO A 1 55  ? -19.12118 -31.76888 7.98157   1.000 14.87812 ? 1514 PRO A O    1 
ATOM   780  C  CB   . PRO A 1 55  ? -19.08096 -30.82993 11.20366  1.000 17.56002 ? 1514 PRO A CB   1 
ATOM   781  C  CG   . PRO A 1 55  ? -18.18836 -30.32951 12.29133  1.000 18.14167 ? 1514 PRO A CG   1 
ATOM   782  C  CD   . PRO A 1 55  ? -17.20451 -29.39128 11.60531  1.000 17.11260 ? 1514 PRO A CD   1 
ATOM   783  H  HA   . PRO A 1 55  ? -17.74441 -31.87106 10.02795  1.000 19.79888 ? 1514 PRO A HA   1 
ATOM   784  H  HB2  . PRO A 1 55  ? -19.78098 -30.19018 10.99971  1.000 21.07482 ? 1514 PRO A HB2  1 
ATOM   785  H  HB3  . PRO A 1 55  ? -19.47190 -31.68705 11.43475  1.000 21.07482 ? 1514 PRO A HB3  1 
ATOM   786  H  HG2  . PRO A 1 55  ? -18.71262 -29.85492 12.95527  1.000 21.77280 ? 1514 PRO A HG2  1 
ATOM   787  H  HG3  . PRO A 1 55  ? -17.72439 -31.07406 12.70519  1.000 21.77280 ? 1514 PRO A HG3  1 
ATOM   788  H  HD2  . PRO A 1 55  ? -17.55743 -28.48882 11.56144  1.000 20.53792 ? 1514 PRO A HD2  1 
ATOM   789  H  HD3  . PRO A 1 55  ? -16.34847 -29.39093 12.06150  1.000 20.53792 ? 1514 PRO A HD3  1 
ATOM   790  N  N    . ALA A 1 56  ? -19.17560 -29.55022 8.31139   1.000 14.62283 ? 1515 ALA A N    1 
ATOM   791  C  CA   . ALA A 1 56  ? -19.86465 -29.33150 7.04414   1.000 14.14645 ? 1515 ALA A CA   1 
ATOM   792  C  C    . ALA A 1 56  ? -18.95914 -29.64607 5.85961   1.000 13.26740 ? 1515 ALA A C    1 
ATOM   793  O  O    . ALA A 1 56  ? -19.40751 -30.19950 4.84975   1.000 13.29372 ? 1515 ALA A O    1 
ATOM   794  C  CB   . ALA A 1 56  ? -20.37142 -27.89395 6.98815   1.000 14.28068 ? 1515 ALA A CB   1 
ATOM   795  H  H    . ALA A 1 56  ? -19.01620 -28.83839 8.76691   1.000 17.55019 ? 1515 ALA A H    1 
ATOM   796  H  HA   . ALA A 1 56  ? -20.63069 -29.92360 6.98501   1.000 16.97854 ? 1515 ALA A HA   1 
ATOM   797  H  HB1  . ALA A 1 56  ? -20.83333 -27.75449 6.14668   1.000 17.13961 ? 1515 ALA A HB1  1 
ATOM   798  H  HB2  . ALA A 1 56  ? -20.98023 -27.74467 7.72839   1.000 17.13961 ? 1515 ALA A HB2  1 
ATOM   799  H  HB3  . ALA A 1 56  ? -19.61545 -27.28980 7.05461   1.000 17.13961 ? 1515 ALA A HB3  1 
ATOM   800  N  N    . LEU A 1 57  ? -17.67230 -29.30913 5.95606   1.000 13.37531 ? 1516 LEU A N    1 
ATOM   801  C  CA   . LEU A 1 57  ? -16.74890 -29.67135 4.88632   1.000 13.77009 ? 1516 LEU A CA   1 
ATOM   802  C  C    . LEU A 1 57  ? -16.63578 -31.18561 4.74058   1.000 14.15698 ? 1516 LEU A C    1 
ATOM   803  O  O    . LEU A 1 57  ? -16.57627 -31.70315 3.61672   1.000 14.52018 ? 1516 LEU A O    1 
ATOM   804  C  CB   . LEU A 1 57  ? -15.38190 -29.03996 5.15025   1.000 14.55440 ? 1516 LEU A CB   1 
ATOM   805  C  CG   . LEU A 1 57  ? -14.29410 -29.38247 4.13599   1.000 15.73612 ? 1516 LEU A CG   1 
ATOM   806  C  CD1  . LEU A 1 57  ? -14.61578 -28.86428 2.74956   1.000 15.64663 ? 1516 LEU A CD1  1 
ATOM   807  C  CD2  . LEU A 1 57  ? -12.93550 -28.80860 4.59887   1.000 16.65991 ? 1516 LEU A CD2  1 
ATOM   808  H  H    . LEU A 1 57  ? -17.31896 -28.88199 6.61355   1.000 16.05317 ? 1516 LEU A H    1 
ATOM   809  H  HA   . LEU A 1 57  ? -17.08244 -29.32190 4.04517   1.000 16.52691 ? 1516 LEU A HA   1 
ATOM   810  H  HB2  . LEU A 1 57  ? -15.48639 -28.07561 5.14816   1.000 17.46807 ? 1516 LEU A HB2  1 
ATOM   811  H  HB3  . LEU A 1 57  ? -15.07148 -29.33814 6.01951   1.000 17.46807 ? 1516 LEU A HB3  1 
ATOM   812  H  HG   . LEU A 1 57  ? -14.23913 -30.34924 4.07899   1.000 18.88614 ? 1516 LEU A HG   1 
ATOM   813  H  HD11 . LEU A 1 57  ? -13.86605 -29.04770 2.16204   1.000 18.77876 ? 1516 LEU A HD11 1 
ATOM   814  H  HD12 . LEU A 1 57  ? -15.41071 -29.31289 2.42132   1.000 18.77876 ? 1516 LEU A HD12 1 
ATOM   815  H  HD13 . LEU A 1 57  ? -14.77178 -27.90814 2.79811   1.000 18.77876 ? 1516 LEU A HD13 1 
ATOM   816  H  HD21 . LEU A 1 57  ? -12.25622 -29.03962 3.94610   1.000 19.99469 ? 1516 LEU A HD21 1 
ATOM   817  H  HD22 . LEU A 1 57  ? -13.00876 -27.84421 4.67285   1.000 19.99469 ? 1516 LEU A HD22 1 
ATOM   818  H  HD23 . LEU A 1 57  ? -12.70884 -29.19025 5.46134   1.000 19.99469 ? 1516 LEU A HD23 1 
ATOM   819  N  N    . ALA A 1 58  ? -16.61335 -31.90562 5.86157   1.000 14.30173 ? 1517 ALA A N    1 
ATOM   820  C  CA   . ALA A 1 58  ? -16.51684 -33.36037 5.80614   1.000 14.38596 ? 1517 ALA A CA   1 
ATOM   821  C  C    . ALA A 1 58  ? -17.72568 -33.95915 5.10757   1.000 14.15435 ? 1517 ALA A C    1 
ATOM   822  O  O    . ALA A 1 58  ? -17.59044 -34.88138 4.30346   1.000 14.13856 ? 1517 ALA A O    1 
ATOM   823  C  CB   . ALA A 1 58  ? -16.40500 -33.91919 7.22077   1.000 14.98076 ? 1517 ALA A CB   1 
ATOM   824  H  H    . ALA A 1 58  ? -16.65223 -31.57997 6.65658   1.000 17.16488 ? 1517 ALA A H    1 
ATOM   825  H  HA   . ALA A 1 58  ? -15.72087 -33.60661 5.30946   1.000 17.26594 ? 1517 ALA A HA   1 
ATOM   826  H  HB1  . ALA A 1 58  ? -16.33431 -34.88548 7.17393   1.000 17.97971 ? 1517 ALA A HB1  1 
ATOM   827  H  HB2  . ALA A 1 58  ? -15.61454 -33.54987 7.64464   1.000 17.97971 ? 1517 ALA A HB2  1 
ATOM   828  H  HB3  . ALA A 1 58  ? -17.19668 -33.66938 7.72251   1.000 17.97971 ? 1517 ALA A HB3  1 
ATOM   829  N  N    . LEU A 1 59  ? -18.91503 -33.46481 5.43387   1.000 13.55428 ? 1518 LEU A N    1 
ATOM   830  C  CA   . LEU A 1 59  ? -20.11630 -33.88967 4.72746   1.000 13.87010 ? 1518 LEU A CA   1 
ATOM   831  C  C    . LEU A 1 59  ? -20.02864 -33.58253 3.24208   1.000 13.17002 ? 1518 LEU A C    1 
ATOM   832  O  O    . LEU A 1 59  ? -20.28883 -34.44094 2.39756   1.000 12.89630 ? 1518 LEU A O    1 
ATOM   833  C  CB   . LEU A 1 59  ? -21.33020 -33.19504 5.33405   1.000 14.50965 ? 1518 LEU A CB   1 
ATOM   834  C  CG   . LEU A 1 59  ? -22.65870 -33.37100 4.58136   1.000 15.57294 ? 1518 LEU A CG   1 
ATOM   835  C  CD1  . LEU A 1 59  ? -23.16630 -34.80579 4.62821   1.000 15.69664 ? 1518 LEU A CD1  1 
ATOM   836  C  CD2  . LEU A 1 59  ? -23.70510 -32.37110 5.13651   1.000 16.27829 ? 1518 LEU A CD2  1 
ATOM   837  H  H    . LEU A 1 59  ? -19.05292 -32.88672 6.05549   1.000 16.26793 ? 1518 LEU A H    1 
ATOM   838  H  HA   . LEU A 1 59  ? -20.21439 -34.84935 4.82891   1.000 16.64692 ? 1518 LEU A HA   1 
ATOM   839  H  HB2  . LEU A 1 59  ? -21.46042 -33.54299 6.23008   1.000 17.41438 ? 1518 LEU A HB2  1 
ATOM   840  H  HB3  . LEU A 1 59  ? -21.14594 -32.24342 5.37122   1.000 17.41438 ? 1518 LEU A HB3  1 
ATOM   841  H  HG   . LEU A 1 59  ? -22.51486 -33.17788 3.64172   1.000 18.69032 ? 1518 LEU A HG   1 
ATOM   842  H  HD11 . LEU A 1 59  ? -24.10707 -34.81581 4.39209   1.000 18.83876 ? 1518 LEU A HD11 1 
ATOM   843  H  HD12 . LEU A 1 59  ? -22.66088 -35.34038 3.99602   1.000 18.83876 ? 1518 LEU A HD12 1 
ATOM   844  H  HD13 . LEU A 1 59  ? -23.04679 -35.15390 5.52567   1.000 18.83876 ? 1518 LEU A HD13 1 
ATOM   845  H  HD21 . LEU A 1 59  ? -24.54046 -32.49008 4.65806   1.000 19.53674 ? 1518 LEU A HD21 1 
ATOM   846  H  HD22 . LEU A 1 59  ? -23.83756 -32.54483 6.08159   1.000 19.53674 ? 1518 LEU A HD22 1 
ATOM   847  H  HD23 . LEU A 1 59  ? -23.37682 -31.46726 5.00918   1.000 19.53674 ? 1518 LEU A HD23 1 
ATOM   848  N  N    . ALA A 1 60  ? -19.71033 -32.33308 2.89605   1.000 13.44110 ? 1519 ALA A N    1 
ATOM   849  C  CA   . ALA A 1 60  ? -19.66019 -31.94587 1.48813   1.000 13.64639 ? 1519 ALA A CA   1 
ATOM   850  C  C    . ALA A 1 60  ? -18.64002 -32.78409 0.71312   1.000 12.56995 ? 1519 ALA A C    1 
ATOM   851  O  O    . ALA A 1 60  ? -18.87616 -33.14034 -0.44440  1.000 12.77524 ? 1519 ALA A O    1 
ATOM   852  C  CB   . ALA A 1 60  ? -19.37207 -30.44689 1.36745   1.000 14.85443 ? 1519 ALA A CB   1 
ATOM   853  H  H    . ALA A 1 60  ? -19.52229 -31.70141 3.44854   1.000 16.13212 ? 1519 ALA A H    1 
ATOM   854  H  HA   . ALA A 1 60  ? -20.52664 -32.10700 1.08292   1.000 16.37847 ? 1519 ALA A HA   1 
ATOM   855  H  HB1  . ALA A 1 60  ? -19.35383 -30.20339 0.42869   1.000 17.82811 ? 1519 ALA A HB1  1 
ATOM   856  H  HB2  . ALA A 1 60  ? -20.07132 -29.95317 1.82372   1.000 17.82811 ? 1519 ALA A HB2  1 
ATOM   857  H  HB3  . ALA A 1 60  ? -18.51278 -30.25663 1.77528   1.000 17.82811 ? 1519 ALA A HB3  1 
ATOM   858  N  N    . GLN A 1 61  ? -17.49398 -33.09095 1.33445   1.000 13.10422 ? 1520 GLN A N    1 
ATOM   859  C  CA   . GLN A 1 61  ? -16.48880 -33.91573 0.66602   1.000 13.67008 ? 1520 GLN A CA   1 
ATOM   860  C  C    . GLN A 1 61  ? -17.05421 -35.28145 0.28472   1.000 12.67259 ? 1520 GLN A C    1 
ATOM   861  O  O    . GLN A 1 61  ? -16.83823 -35.76144 -0.82851  1.000 12.72523 ? 1520 GLN A O    1 
ATOM   862  C  CB   . GLN A 1 61  ? -15.26471 -34.12020 1.56742   1.000 16.08616 ? 1520 GLN A CB   1 
ATOM   863  C  CG   . GLN A 1 61  ? -14.26179 -32.99009 1.57174   1.000 18.99177 ? 1520 GLN A CG   1 
ATOM   864  C  CD   . GLN A 1 61  ? -13.26715 -33.07120 2.73523   1.000 21.81053 ? 1520 GLN A CD   1 
ATOM   865  O  OE1  . GLN A 1 61  ? -13.48214 -33.77877 3.73579   1.000 22.85539 ? 1520 GLN A OE1  1 
ATOM   866  N  NE2  . GLN A 1 61  ? -12.14733 -32.40103 2.57552   1.000 23.52126 ? 1520 GLN A NE2  1 
ATOM   867  H  H    . GLN A 1 61  ? -17.28036 -32.83776 2.12809   1.000 15.72786 ? 1520 GLN A H    1 
ATOM   868  H  HA   . GLN A 1 61  ? -16.21092 -33.44691 -0.13640  1.000 16.40689 ? 1520 GLN A HA   1 
ATOM   869  H  HB2  . GLN A 1 61  ? -15.57380 -34.23490 2.47967   1.000 19.30619 ? 1520 GLN A HB2  1 
ATOM   870  H  HB3  . GLN A 1 61  ? -14.79877 -34.91810 1.27220   1.000 19.30619 ? 1520 GLN A HB3  1 
ATOM   871  H  HG2  . GLN A 1 61  ? -13.75582 -33.01541 0.74454   1.000 22.79292 ? 1520 GLN A HG2  1 
ATOM   872  H  HG3  . GLN A 1 61  ? -14.73735 -32.14778 1.64411   1.000 22.79292 ? 1520 GLN A HG3  1 
ATOM   873  H  HE21 . GLN A 1 61  ? -12.01223 -31.95550 1.85244   1.000 28.22831 ? 1520 GLN A HE21 1 
ATOM   874  H  HE22 . GLN A 1 61  ? -11.54995 -32.40820 3.19414   1.000 28.22831 ? 1520 GLN A HE22 1 
ATOM   875  N  N    . LYS A 1 62  ? -17.78839 -35.91196 1.19555   1.000 12.94368 ? 1521 LYS A N    1 
ATOM   876  C  CA   . LYS A 1 62  ? -18.32622 -37.22876 0.87984   1.000 13.48058 ? 1521 LYS A CA   1 
ATOM   877  C  C    . LYS A 1 62  ? -19.42872 -37.13758 -0.16491  1.000 13.30688 ? 1521 LYS A C    1 
ATOM   878  O  O    . LYS A 1 62  ? -19.51031 -37.98884 -1.05573  1.000 14.14645 ? 1521 LYS A O    1 
ATOM   879  C  CB   . LYS A 1 62  ? -18.85319 -37.90276 2.13727   1.000 14.95445 ? 1521 LYS A CB   1 
ATOM   880  C  CG   . LYS A 1 62  ? -17.83228 -38.12754 3.25933   1.000 17.67845 ? 1521 LYS A CG   1 
ATOM   881  C  CD   . LYS A 1 62  ? -16.49193 -38.59284 2.82437   1.000 20.46036 ? 1521 LYS A CD   1 
ATOM   882  C  CE   . LYS A 1 62  ? -16.52290 -39.95062 2.30515   1.000 21.41838 ? 1521 LYS A CE   1 
ATOM   883  N  NZ   . LYS A 1 62  ? -15.15469 -40.64388 2.36586   1.000 22.52903 ? 1521 LYS A NZ   1 
ATOM   884  H  H    . LYS A 1 62  ? -17.98322 -35.60996 1.97686   1.000 15.53521 ? 1521 LYS A H    1 
ATOM   885  H  HA   . LYS A 1 62  ? -17.60802 -37.77471 0.52344   1.000 16.17950 ? 1521 LYS A HA   1 
ATOM   886  H  HB2  . LYS A 1 62  ? -19.56264 -37.35091 2.50205   1.000 17.94813 ? 1521 LYS A HB2  1 
ATOM   887  H  HB3  . LYS A 1 62  ? -19.20344 -38.77296 1.89034   1.000 17.94813 ? 1521 LYS A HB3  1 
ATOM   888  H  HG2  . LYS A 1 62  ? -17.70627 -37.28882 3.73004   1.000 21.21694 ? 1521 LYS A HG2  1 
ATOM   889  H  HG3  . LYS A 1 62  ? -18.18640 -38.79772 3.86460   1.000 21.21694 ? 1521 LYS A HG3  1 
ATOM   890  H  HD2  . LYS A 1 62  ? -16.16422 -38.00880 2.12265   1.000 24.55523 ? 1521 LYS A HD2  1 
ATOM   891  H  HD3  . LYS A 1 62  ? -15.88657 -38.57320 3.58203   1.000 24.55523 ? 1521 LYS A HD3  1 
ATOM   892  H  HE2  . LYS A 1 62  ? -17.14773 -40.47525 2.82979   1.000 25.70485 ? 1521 LYS A HE2  1 
ATOM   893  H  HE3  . LYS A 1 62  ? -16.80588 -39.92774 1.37763   1.000 25.70485 ? 1521 LYS A HE3  1 
ATOM   894  H  HZ1  . LYS A 1 62  ? -14.55965 -40.18530 1.88864   1.000 27.03764 ? 1521 LYS A HZ1  1 
ATOM   895  H  HZ2  . LYS A 1 62  ? -14.87429 -40.69063 3.20924   1.000 27.03764 ? 1521 LYS A HZ2  1 
ATOM   896  H  HZ3  . LYS A 1 62  ? -15.21617 -41.46813 2.03581   1.000 27.03764 ? 1521 LYS A HZ3  1 
ATOM   897  N  N    . LEU A 1 63  ? -20.27894 -36.10936 -0.08769  1.000 13.38320 ? 1522 LEU A N    1 
ATOM   898  C  CA   . LEU A 1 63  ? -21.30741 -35.95649 -1.11641  1.000 13.40163 ? 1522 LEU A CA   1 
ATOM   899  C  C    . LEU A 1 63  ? -20.66728 -35.74334 -2.47732  1.000 13.16213 ? 1522 LEU A C    1 
ATOM   900  O  O    . LEU A 1 63  ? -21.11132 -36.29290 -3.48598  1.000 13.73061 ? 1522 LEU A O    1 
ATOM   901  C  CB   . LEU A 1 63  ? -22.24249 -34.79669 -0.76413  1.000 14.10434 ? 1522 LEU A CB   1 
ATOM   902  C  CG   . LEU A 1 63  ? -23.03428 -35.01546 0.52731   1.000 15.38871 ? 1522 LEU A CG   1 
ATOM   903  C  CD1  . LEU A 1 63  ? -23.83307 -33.77088 0.87388   1.000 15.88613 ? 1522 LEU A CD1  1 
ATOM   904  C  CD2  . LEU A 1 63  ? -23.97074 -36.23281 0.41933   1.000 16.11774 ? 1522 LEU A CD2  1 
ATOM   905  H  H    . LEU A 1 63  ? -20.28091 -35.50874 0.52782   1.000 16.06264 ? 1522 LEU A H    1 
ATOM   906  H  HA   . LEU A 1 63  ? -21.84687 -36.76178 -1.15361  1.000 16.08475 ? 1522 LEU A HA   1 
ATOM   907  H  HB2  . LEU A 1 63  ? -21.71259 -33.99159 -0.65491  1.000 16.92801 ? 1522 LEU A HB2  1 
ATOM   908  H  HB3  . LEU A 1 63  ? -22.87905 -34.67942 -1.48659  1.000 16.92801 ? 1522 LEU A HB3  1 
ATOM   909  H  HG   . LEU A 1 63  ? -22.40410 -35.19386 1.24282   1.000 18.46925 ? 1522 LEU A HG   1 
ATOM   910  H  HD11 . LEU A 1 63  ? -24.32480 -33.92966 1.69479   1.000 19.06616 ? 1522 LEU A HD11 1 
ATOM   911  H  HD12 . LEU A 1 63  ? -23.22242 -33.02665 0.99275   1.000 19.06616 ? 1522 LEU A HD12 1 
ATOM   912  H  HD13 . LEU A 1 63  ? -24.45021 -33.58006 0.15026   1.000 19.06616 ? 1522 LEU A HD13 1 
ATOM   913  H  HD21 . LEU A 1 63  ? -24.56506 -36.24303 1.18587   1.000 19.34409 ? 1522 LEU A HD21 1 
ATOM   914  H  HD22 . LEU A 1 63  ? -24.48719 -36.16237 -0.39873  1.000 19.34409 ? 1522 LEU A HD22 1 
ATOM   915  H  HD23 . LEU A 1 63  ? -23.43621 -37.04210 0.40441   1.000 19.34409 ? 1522 LEU A HD23 1 
ATOM   916  N  N    . ALA A 1 64  ? -19.62541 -34.90838 -2.53361  1.000 12.94105 ? 1523 ALA A N    1 
ATOM   917  C  CA   . ALA A 1 64  ? -18.96066 -34.67824 -3.80351  1.000 12.53310 ? 1523 ALA A CA   1 
ATOM   918  C  C    . ALA A 1 64  ? -18.23955 -35.92493 -4.30871  1.000 12.18043 ? 1523 ALA A C    1 
ATOM   919  O  O    . ALA A 1 64  ? -18.29320 -36.24385 -5.50076  1.000 12.24886 ? 1523 ALA A O    1 
ATOM   920  C  CB   . ALA A 1 64  ? -17.98812 -33.51314 -3.63400  1.000 12.83051 ? 1523 ALA A CB   1 
ATOM   921  H  H    . ALA A 1 64  ? -19.29727 -34.47730 -1.86571  1.000 15.53205 ? 1523 ALA A H    1 
ATOM   922  H  HA   . ALA A 1 64  ? -19.61968 -34.44816 -4.47704  1.000 15.04252 ? 1523 ALA A HA   1 
ATOM   923  H  HB1  . ALA A 1 64  ? -17.57268 -33.32155 -4.48934  1.000 15.39940 ? 1523 ALA A HB1  1 
ATOM   924  H  HB2  . ALA A 1 64  ? -18.47773 -32.73584 -3.32257  1.000 15.39940 ? 1523 ALA A HB2  1 
ATOM   925  H  HB3  . ALA A 1 64  ? -17.31058 -33.75920 -2.98493  1.000 15.39940 ? 1523 ALA A HB3  1 
ATOM   926  N  N    . GLU A 1 65  ? -17.54999 -36.64188 -3.42869  1.000 13.21213 ? 1524 GLU A N    1 
ATOM   927  C  CA   . GLU A 1 65  ? -16.84777 -37.84279 -3.88398  1.000 14.04118 ? 1524 GLU A CA   1 
ATOM   928  C  C    . GLU A 1 65  ? -17.80252 -38.88464 -4.44522  1.000 14.41754 ? 1524 GLU A C    1 
ATOM   929  O  O    . GLU A 1 65  ? -17.42455 -39.65211 -5.34101  1.000 16.00720 ? 1524 GLU A O    1 
ATOM   930  C  CB   . GLU A 1 65  ? -16.01779 -38.43318 -2.74929  1.000 14.52545 ? 1524 GLU A CB   1 
ATOM   931  C  CG   . GLU A 1 65  ? -14.78645 -37.53322 -2.48353  1.000 15.55978 ? 1524 GLU A CG   1 
ATOM   932  C  CD   . GLU A 1 65  ? -13.84418 -38.08389 -1.43781  1.000 17.72057 ? 1524 GLU A CD   1 
ATOM   933  O  OE1  . GLU A 1 65  ? -14.29852 -38.87645 -0.59826  1.000 19.21285 ? 1524 GLU A OE1  1 
ATOM   934  O  OE2  . GLU A 1 65  ? -12.64928 -37.72118 -1.45240  1.000 18.23642 ? 1524 GLU A OE2  1 
ATOM   935  H  H    . GLU A 1 65  ? -17.47299 -36.46427 -2.59076  1.000 15.85735 ? 1524 GLU A H    1 
ATOM   936  H  HA   . GLU A 1 65  ? -16.23984 -37.58901 -4.59596  1.000 16.85221 ? 1524 GLU A HA   1 
ATOM   937  H  HB2  . GLU A 1 65  ? -16.55282 -38.47911 -1.94149  1.000 17.43333 ? 1524 GLU A HB2  1 
ATOM   938  H  HB3  . GLU A 1 65  ? -15.71090 -39.31998 -2.99483  1.000 17.43333 ? 1524 GLU A HB3  1 
ATOM   939  H  HG2  . GLU A 1 65  ? -14.28712 -37.43540 -3.30935  1.000 18.67454 ? 1524 GLU A HG2  1 
ATOM   940  H  HG3  . GLU A 1 65  ? -15.09398 -36.66581 -2.17705  1.000 18.67454 ? 1524 GLU A HG3  1 
ATOM   941  N  N    . ALA A 1 66  ? -19.03429 -38.92052 -3.94148  1.000 13.69640 ? 1525 ALA A N    1 
ATOM   942  C  CA   . ALA A 1 66  ? -20.03035 -39.89607 -4.36971  1.000 14.28068 ? 1525 ALA A CA   1 
ATOM   943  C  C    . ALA A 1 66  ? -20.81925 -39.42223 -5.57479  1.000 14.00696 ? 1525 ALA A C    1 
ATOM   944  O  O    . ALA A 1 66  ? -21.34390 -40.24745 -6.33237  1.000 14.39911 ? 1525 ALA A O    1 
ATOM   945  C  CB   . ALA A 1 66  ? -21.00677 -40.15124 -3.22186  1.000 15.14131 ? 1525 ALA A CB   1 
ATOM   946  H  H    . ALA A 1 66  ? -19.32271 -38.37944 -3.33845  1.000 16.43848 ? 1525 ALA A H    1 
ATOM   947  H  HA   . ALA A 1 66  ? -19.58673 -40.72715 -4.60079  1.000 17.13961 ? 1525 ALA A HA   1 
ATOM   948  H  HB1  . ALA A 1 66  ? -21.66880 -40.79959 -3.50865  1.000 18.17237 ? 1525 ALA A HB1  1 
ATOM   949  H  HB2  . ALA A 1 66  ? -20.51522 -40.49539 -2.45973  1.000 18.17237 ? 1525 ALA A HB2  1 
ATOM   950  H  HB3  . ALA A 1 66  ? -21.44152 -39.31690 -2.98570  1.000 18.17237 ? 1525 ALA A HB3  1 
ATOM   951  N  N    . GLY A 1 67  ? -20.94605 -38.10864 -5.76011  1.000 13.39636 ? 1526 GLY A N    1 
ATOM   952  C  CA   . GLY A 1 67  ? -21.79034 -37.58657 -6.80857  1.000 12.73576 ? 1526 GLY A CA   1 
ATOM   953  C  C    . GLY A 1 67  ? -21.08623 -36.96671 -7.99507  1.000 12.66733 ? 1526 GLY A C    1 
ATOM   954  O  O    . GLY A 1 67  ? -21.63403 -36.95220 -9.09054  1.000 13.61744 ? 1526 GLY A O    1 
ATOM   955  H  H    . GLY A 1 67  ? -20.55092 -37.50778 -5.28848  1.000 16.07843 ? 1526 GLY A H    1 
ATOM   956  H  HA2  . GLY A 1 67  ? -22.34046 -38.31076 -7.14594  1.000 15.28571 ? 1526 GLY A HA2  1 
ATOM   957  H  HA3  . GLY A 1 67  ? -22.36507 -36.90512 -6.42619  1.000 15.28571 ? 1526 GLY A HA3  1 
ATOM   958  N  N    . ALA A 1 68  ? -19.87871 -36.42581 -7.80394  1.000 12.89367 ? 1527 ALA A N    1 
ATOM   959  C  CA   . ALA A 1 68  ? -19.23855 -35.70180 -8.88685  1.000 12.37782 ? 1527 ALA A CA   1 
ATOM   960  C  C    . ALA A 1 68  ? -18.80932 -36.64514 -9.99962  1.000 12.43046 ? 1527 ALA A C    1 
ATOM   961  O  O    . ALA A 1 68  ? -18.28254 -37.73139 -9.74176  1.000 13.10422 ? 1527 ALA A O    1 
ATOM   962  C  CB   . ALA A 1 68  ? -17.98610 -34.99648 -8.36608  1.000 12.61732 ? 1527 ALA A CB   1 
ATOM   963  H  H    . ALA A 1 68  ? -19.42678 -36.46670 -7.07340  1.000 15.47520 ? 1527 ALA A H    1 
ATOM   964  H  HA   . ALA A 1 68  ? -19.86882 -35.05503 -9.24087  1.000 14.85618 ? 1527 ALA A HA   1 
ATOM   965  H  HB1  . ALA A 1 68  ? -17.55260 -34.53784 -9.10271  1.000 15.14358 ? 1527 ALA A HB1  1 
ATOM   966  H  HB2  . ALA A 1 68  ? -18.24440 -34.35676 -7.68421  1.000 15.14358 ? 1527 ALA A HB2  1 
ATOM   967  H  HB3  . ALA A 1 68  ? -17.38517 -35.65776 -7.98859  1.000 15.14358 ? 1527 ALA A HB3  1 
ATOM   968  N  N    . ARG A 1 69  ? -18.93237 -36.17053 -11.23706 1.000 12.36466 ? 1528 ARG A N    1 
ATOM   969  C  CA   . ARG A 1 69  ? -18.48418 -36.89306 -12.41379 1.000 12.90420 ? 1528 ARG A CA   1 
ATOM   970  C  C    . ARG A 1 69  ? -17.19436 -36.32265 -12.97103 1.000 13.22266 ? 1528 ARG A C    1 
ATOM   971  O  O    . ARG A 1 69  ? -16.52522 -36.98600 -13.75157 1.000 13.73851 ? 1528 ARG A O    1 
ATOM   972  C  CB   . ARG A 1 69  ? -19.53959 -36.81576 -13.51652 1.000 13.64113 ? 1528 ARG A CB   1 
ATOM   973  C  CG   . ARG A 1 69  ? -20.92709 -37.33341 -13.12436 1.000 13.76220 ? 1528 ARG A CG   1 
ATOM   974  C  CD   . ARG A 1 69  ? -21.90681 -36.94318 -14.19846 1.000 14.74916 ? 1528 ARG A CD   1 
ATOM   975  N  NE   . ARG A 1 69  ? -23.29201 -37.23064 -13.84069 1.000 14.76232 ? 1528 ARG A NE   1 
ATOM   976  C  CZ   . ARG A 1 69  ? -23.91244 -38.36768 -14.14083 1.000 15.47030 ? 1528 ARG A CZ   1 
ATOM   977  N  NH1  . ARG A 1 69  ? -23.27657 -39.35647 -14.73018 1.000 16.66254 ? 1528 ARG A NH1  1 
ATOM   978  N  NH2  . ARG A 1 69  ? -25.20697 -38.50823 -13.85223 1.000 16.54147 ? 1528 ARG A NH2  1 
ATOM   979  H  H    . ARG A 1 69  ? -19.28377 -35.40786 -11.42270 1.000 14.84039 ? 1528 ARG A H    1 
ATOM   980  H  HA   . ARG A 1 69  ? -18.35387 -37.82586 -12.18183 1.000 15.48784 ? 1528 ARG A HA   1 
ATOM   981  H  HB2  . ARG A 1 69  ? -19.63968 -35.88783 -13.78077 1.000 16.37215 ? 1528 ARG A HB2  1 
ATOM   982  H  HB3  . ARG A 1 69  ? -19.23468 -37.34438 -14.27050 1.000 16.37215 ? 1528 ARG A HB3  1 
ATOM   983  H  HG2  . ARG A 1 69  ? -20.91111 -38.30011 -13.04605 1.000 16.51743 ? 1528 ARG A HG2  1 
ATOM   984  H  HG3  . ARG A 1 69  ? -21.20415 -36.93699 -12.28353 1.000 16.51743 ? 1528 ARG A HG3  1 
ATOM   985  H  HD2  . ARG A 1 69  ? -21.83239 -35.98989 -14.36158 1.000 17.70178 ? 1528 ARG A HD2  1 
ATOM   986  H  HD3  . ARG A 1 69  ? -21.69938 -37.43548 -15.00809 1.000 17.70178 ? 1528 ARG A HD3  1 
ATOM   987  H  HE   . ARG A 1 69  ? -23.73250 -36.62993 -13.41091 1.000 17.71758 ? 1528 ARG A HE   1 
ATOM   988  H  HH11 . ARG A 1 69  ? -22.44382 -39.27452 -14.92868 1.000 19.99785 ? 1528 ARG A HH11 1 
ATOM   989  H  HH12 . ARG A 1 69  ? -23.69349 -40.08506 -14.91709 1.000 19.99785 ? 1528 ARG A HH12 1 
ATOM   990  H  HH21 . ARG A 1 69  ? -25.63549 -37.86553 -13.47419 1.000 19.85257 ? 1528 ARG A HH21 1 
ATOM   991  H  HH22 . ARG A 1 69  ? -25.61317 -39.24155 -14.04418 1.000 19.85257 ? 1528 ARG A HH22 1 
ATOM   992  N  N    . CYS A 1 70  ? -16.87436 -35.08062 -12.64140 1.000 12.78576 ? 1529 CYS A N    1 
ATOM   993  C  CA   . CYS A 1 70  ? -15.57595 -34.49828 -12.94723 1.000 12.48836 ? 1529 CYS A CA   1 
ATOM   994  C  C    . CYS A 1 70  ? -14.86456 -34.18693 -11.64076 1.000 11.35138 ? 1529 CYS A C    1 
ATOM   995  O  O    . CYS A 1 70  ? -15.42305 -34.31932 -10.55927 1.000 11.56720 ? 1529 CYS A O    1 
ATOM   996  C  CB   . CYS A 1 70  ? -15.71395 -33.25029 -13.82220 1.000 12.15148 ? 1529 CYS A CB   1 
ATOM   997  S  SG   . CYS A 1 70  ? -16.39479 -31.77309 -13.04880 1.000 12.98842 ? 1529 CYS A SG   1 
ATOM   998  H  H    . CYS A 1 70  ? -17.40484 -34.54277 -12.23043 1.000 15.34571 ? 1529 CYS A H    1 
ATOM   999  H  HA   . CYS A 1 70  ? -15.03500 -35.12978 -13.44672 1.000 14.98883 ? 1529 CYS A HA   1 
ATOM   1000 H  HB2  . CYS A 1 70  ? -14.83105 -33.01563 -14.14828 1.000 14.58457 ? 1529 CYS A HB2  1 
ATOM   1001 H  HB3  . CYS A 1 70  ? -16.29484 -33.47106 -14.56700 1.000 14.58457 ? 1529 CYS A HB3  1 
ATOM   1002 H  HG   . CYS A 1 70  ? -15.69835 -31.46052 -12.12291 1.000 15.58890 ? 1529 CYS A HG   1 
ATOM   1003 N  N    . ASP A 1 71  ? -13.60005 -33.76315 -11.73532 1.000 11.73564 ? 1530 ASP A N    1 
ATOM   1004 C  CA   . ASP A 1 71  ? -12.83444 -33.50871 -10.52369 1.000 11.62773 ? 1530 ASP A CA   1 
ATOM   1005 C  C    . ASP A 1 71  ? -13.19519 -32.13951 -9.94624  1.000 10.58550 ? 1530 ASP A C    1 
ATOM   1006 O  O    . ASP A 1 71  ? -13.79248 -31.27187 -10.61279 1.000 11.06187 ? 1530 ASP A O    1 
ATOM   1007 C  CB   . ASP A 1 71  ? -11.33497 -33.66803 -10.80499 1.000 11.85407 ? 1530 ASP A CB   1 
ATOM   1008 C  CG   . ASP A 1 71  ? -10.98623 -35.07347 -11.26738 1.000 12.11726 ? 1530 ASP A CG   1 
ATOM   1009 O  OD1  . ASP A 1 71  ? -11.64676 -36.01814 -10.78522 1.000 12.97526 ? 1530 ASP A OD1  1 
ATOM   1010 O  OD2  . ASP A 1 71  ? -10.08402 -35.21928 -12.12202 1.000 12.28044 ? 1530 ASP A OD2  1 
ATOM   1011 H  H    . ASP A 1 71  ? -13.17899 -33.62085 -12.47157 1.000 14.08556 ? 1530 ASP A H    1 
ATOM   1012 H  HA   . ASP A 1 71  ? -13.04964 -34.15560 -9.83367  1.000 13.95607 ? 1530 ASP A HA   1 
ATOM   1013 H  HB2  . ASP A 1 71  ? -11.07375 -33.04636 -11.50227 1.000 14.22769 ? 1530 ASP A HB2  1 
ATOM   1014 H  HB3  . ASP A 1 71  ? -10.83714 -33.48417 -9.99305  1.000 14.22769 ? 1530 ASP A HB3  1 
ATOM   1015 N  N    . PHE A 1 72  ? -12.85563 -31.95553 -8.67735  1.000 10.30915 ? 1531 PHE A N    1 
ATOM   1016 C  CA   . PHE A 1 72  ? -13.34181 -30.77133 -7.97431  1.000 10.39074 ? 1531 PHE A CA   1 
ATOM   1017 C  C    . PHE A 1 72  ? -12.43165 -30.40388 -6.80892  1.000 10.64867 ? 1531 PHE A C    1 
ATOM   1018 O  O    . PHE A 1 72  ? -11.58764 -31.18051 -6.35110  1.000 11.07240 ? 1531 PHE A O    1 
ATOM   1019 C  CB   . PHE A 1 72  ? -14.77778 -31.01637 -7.44779  1.000 10.56971 ? 1531 PHE A CB   1 
ATOM   1020 C  CG   . PHE A 1 72  ? -14.82789 -32.15983 -6.45207  1.000 10.69341 ? 1531 PHE A CG   1 
ATOM   1021 C  CD1  . PHE A 1 72  ? -14.57456 -31.93354 -5.10747  1.000 11.18031 ? 1531 PHE A CD1  1 
ATOM   1022 C  CD2  . PHE A 1 72  ? -15.04132 -33.46527 -6.86999  1.000 11.35401 ? 1531 PHE A CD2  1 
ATOM   1023 C  CE1  . PHE A 1 72  ? -14.54446 -32.96842 -4.19093  1.000 11.63036 ? 1531 PHE A CE1  1 
ATOM   1024 C  CE2  . PHE A 1 72  ? -15.03119 -34.51584 -5.95594  1.000 11.21715 ? 1531 PHE A CE2  1 
ATOM   1025 C  CZ   . PHE A 1 72  ? -14.78834 -34.28170 -4.62724  1.000 11.45929 ? 1531 PHE A CZ   1 
ATOM   1026 H  H    . PHE A 1 72  ? -12.36036 -32.48404 -8.21370  1.000 12.37378 ? 1531 PHE A H    1 
ATOM   1027 H  HA   . PHE A 1 72  ? -13.32121 -30.02467 -8.59316  1.000 12.47169 ? 1531 PHE A HA   1 
ATOM   1028 H  HB2  . PHE A 1 72  ? -15.09669 -30.21409 -7.00557  1.000 12.68645 ? 1531 PHE A HB2  1 
ATOM   1029 H  HB3  . PHE A 1 72  ? -15.35767 -31.23701 -8.19341  1.000 12.68645 ? 1531 PHE A HB3  1 
ATOM   1030 H  HD1  . PHE A 1 72  ? -14.42111 -31.06417 -4.81499  1.000 13.41917 ? 1531 PHE A HD1  1 
ATOM   1031 H  HD2  . PHE A 1 72  ? -15.19287 -33.64079 -7.77061  1.000 13.62761 ? 1531 PHE A HD2  1 
ATOM   1032 H  HE1  . PHE A 1 72  ? -14.36463 -32.79701 -3.29473  1.000 13.95923 ? 1531 PHE A HE1  1 
ATOM   1033 H  HE2  . PHE A 1 72  ? -15.19054 -35.38380 -6.24946  1.000 13.46338 ? 1531 PHE A HE2  1 
ATOM   1034 H  HZ   . PHE A 1 72  ? -14.78503 -34.98595 -4.01985  1.000 13.75394 ? 1531 PHE A HZ   1 
ATOM   1035 N  N    . ALA A 1 73  ? -12.62958 -29.17256 -6.33847  1.000 10.65919 ? 1532 ALA A N    1 
ATOM   1036 C  CA   . ALA A 1 73  ? -12.15782 -28.71722 -5.05172  1.000 10.35389 ? 1532 ALA A CA   1 
ATOM   1037 C  C    . ALA A 1 73  ? -13.31108 -27.94150 -4.42612  1.000 10.19598 ? 1532 ALA A C    1 
ATOM   1038 O  O    . ALA A 1 73  ? -14.11903 -27.32925 -5.13839  1.000 10.62761 ? 1532 ALA A O    1 
ATOM   1039 C  CB   . ALA A 1 73  ? -10.88664 -27.85389 -5.15429  1.000 11.01713 ? 1532 ALA A CB   1 
ATOM   1040 H  H    . ALA A 1 73  ? -13.05390 -28.56287 -6.77186  1.000 12.79383 ? 1532 ALA A H    1 
ATOM   1041 H  HA   . ALA A 1 73  ? -11.91636 -29.46277 -4.48009  1.000 12.42747 ? 1532 ALA A HA   1 
ATOM   1042 H  HB1  . ALA A 1 73  ? -10.61966 -27.57784 -4.26355  1.000 13.22335 ? 1532 ALA A HB1  1 
ATOM   1043 H  HB2  . ALA A 1 73  ? -10.18078 -28.37849 -5.56349  1.000 13.22335 ? 1532 ALA A HB2  1 
ATOM   1044 H  HB3  . ALA A 1 73  ? -11.07750 -27.07424 -5.69892  1.000 13.22335 ? 1532 ALA A HB3  1 
ATOM   1045 N  N    . LEU A 1 74  ? -13.37790 -27.95995 -3.10631  1.000 10.39337 ? 1533 LEU A N    1 
ATOM   1046 C  CA   . LEU A 1 74  ? -14.47134 -27.32163 -2.37661  1.000 10.89343 ? 1533 LEU A CA   1 
ATOM   1047 C  C    . LEU A 1 74  ? -13.96995 -26.09912 -1.61874  1.000 9.83278  ? 1533 LEU A C    1 
ATOM   1048 O  O    . LEU A 1 74  ? -13.04314 -26.20095 -0.81132  1.000 10.82237 ? 1533 LEU A O    1 
ATOM   1049 C  CB   . LEU A 1 74  ? -15.09211 -28.29817 -1.37110  1.000 12.20938 ? 1533 LEU A CB   1 
ATOM   1050 C  CG   . LEU A 1 74  ? -15.59931 -29.61641 -1.95675  1.000 13.75167 ? 1533 LEU A CG   1 
ATOM   1051 C  CD1  . LEU A 1 74  ? -16.18129 -30.46942 -0.85143  1.000 15.95982 ? 1533 LEU A CD1  1 
ATOM   1052 C  CD2  . LEU A 1 74  ? -16.62005 -29.38225 -3.05220  1.000 13.48848 ? 1533 LEU A CD2  1 
ATOM   1053 H  H    . LEU A 1 74  ? -12.79575 -28.34010 -2.60018  1.000 12.47484 ? 1533 LEU A H    1 
ATOM   1054 H  HA   . LEU A 1 74  ? -15.13954 -27.03429 -3.01836  1.000 13.07491 ? 1533 LEU A HA   1 
ATOM   1055 H  HB2  . LEU A 1 74  ? -14.42094 -28.51691 -0.70583  1.000 14.65405 ? 1533 LEU A HB2  1 
ATOM   1056 H  HB3  . LEU A 1 74  ? -15.84750 -27.86013 -0.94870  1.000 14.65405 ? 1533 LEU A HB3  1 
ATOM   1057 H  HG   . LEU A 1 74  ? -14.85651 -30.09043 -2.36227  1.000 16.50480 ? 1533 LEU A HG   1 
ATOM   1058 H  HD11 . LEU A 1 74  ? -16.50136 -31.30276 -1.23090  1.000 19.15459 ? 1533 LEU A HD11 1 
ATOM   1059 H  HD12 . LEU A 1 74  ? -15.49082 -30.64887 -0.19420  1.000 19.15459 ? 1533 LEU A HD12 1 
ATOM   1060 H  HD13 . LEU A 1 74  ? -16.91619 -29.99090 -0.43690  1.000 19.15459 ? 1533 LEU A HD13 1 
ATOM   1061 H  HD21 . LEU A 1 74  ? -16.99145 -30.23565 -3.32544  1.000 16.18897 ? 1533 LEU A HD21 1 
ATOM   1062 H  HD22 . LEU A 1 74  ? -17.32418 -28.80924 -2.71050  1.000 16.18897 ? 1533 LEU A HD22 1 
ATOM   1063 H  HD23 . LEU A 1 74  ? -16.18261 -28.95546 -3.80546  1.000 16.18897 ? 1533 LEU A HD23 1 
ATOM   1064 N  N    . PHE A 1 75  ? -14.61597 -24.95302 -1.83543  1.000 10.26704 ? 1534 PHE A N    1 
ATOM   1065 C  CA   . PHE A 1 75  ? -14.28258 -23.77093 -1.05070  1.000 9.82488  ? 1534 PHE A CA   1 
ATOM   1066 C  C    . PHE A 1 75  ? -14.81799 -23.90554 0.37432   1.000 10.05649 ? 1534 PHE A C    1 
ATOM   1067 O  O    . PHE A 1 75  ? -15.88790 -24.48610 0.60438   1.000 11.26189 ? 1534 PHE A O    1 
ATOM   1068 C  CB   . PHE A 1 75  ? -14.90808 -22.51446 -1.66007  1.000 10.10913 ? 1534 PHE A CB   1 
ATOM   1069 C  CG   . PHE A 1 75  ? -14.14743 -21.92885 -2.80037  1.000 9.94332  ? 1534 PHE A CG   1 
ATOM   1070 C  CD1  . PHE A 1 75  ? -13.04222 -21.12083 -2.55904  1.000 10.16440 ? 1534 PHE A CD1  1 
ATOM   1071 C  CD2  . PHE A 1 75  ? -14.51494 -22.17808 -4.11098  1.000 10.79868 ? 1534 PHE A CD2  1 
ATOM   1072 C  CE1  . PHE A 1 75  ? -12.33612 -20.56967 -3.61152  1.000 10.80658 ? 1534 PHE A CE1  1 
ATOM   1073 C  CE2  . PHE A 1 75  ? -13.82798 -21.61931 -5.15635  1.000 11.47245 ? 1534 PHE A CE2  1 
ATOM   1074 C  CZ   . PHE A 1 75  ? -12.73773 -20.81311 -4.91366  1.000 11.01450 ? 1534 PHE A CZ   1 
ATOM   1075 H  H    . PHE A 1 75  ? -15.23743 -24.83853 -2.41877  1.000 12.32324 ? 1534 PHE A H    1 
ATOM   1076 H  HA   . PHE A 1 75  ? -13.31728 -23.67646 -1.03813  1.000 11.79266 ? 1534 PHE A HA   1 
ATOM   1077 H  HB2  . PHE A 1 75  ? -15.79440 -22.73800 -1.98466  1.000 12.13375 ? 1534 PHE A HB2  1 
ATOM   1078 H  HB3  . PHE A 1 75  ? -14.96892 -21.83513 -0.97035  1.000 12.13375 ? 1534 PHE A HB3  1 
ATOM   1079 H  HD1  . PHE A 1 75  ? -12.77646 -20.95019 -1.68431  1.000 12.20007 ? 1534 PHE A HD1  1 
ATOM   1080 H  HD2  . PHE A 1 75  ? -15.24000 -22.73388 -4.28499  1.000 12.96122 ? 1534 PHE A HD2  1 
ATOM   1081 H  HE1  . PHE A 1 75  ? -11.59265 -20.03628 -3.44523  1.000 12.97069 ? 1534 PHE A HE1  1 
ATOM   1082 H  HE2  . PHE A 1 75  ? -14.09802 -21.78449 -6.03082  1.000 13.76973 ? 1534 PHE A HE2  1 
ATOM   1083 H  HZ   . PHE A 1 75  ? -12.27227 -20.43302 -5.62343  1.000 13.22020 ? 1534 PHE A HZ   1 
ATOM   1084 N  N    . LEU A 1 76  ? -14.11851 -23.28207 1.32315   1.000 10.25388 ? 1535 LEU A N    1 
ATOM   1085 C  CA   . LEU A 1 76  ? -14.66633 -22.94371 2.63062   1.000 10.25125 ? 1535 LEU A CA   1 
ATOM   1086 C  C    . LEU A 1 76  ? -15.22236 -21.52496 2.54706   1.000 9.86173  ? 1535 LEU A C    1 
ATOM   1087 O  O    . LEU A 1 76  ? -14.76520 -20.71416 1.74578   1.000 10.88553 ? 1535 LEU A O    1 
ATOM   1088 C  CB   . LEU A 1 76  ? -13.57377 -22.98223 3.68654   1.000 10.77763 ? 1535 LEU A CB   1 
ATOM   1089 C  CG   . LEU A 1 76  ? -13.35347 -24.36956 4.26876   1.000 11.93829 ? 1535 LEU A CG   1 
ATOM   1090 C  CD1  . LEU A 1 76  ? -11.97411 -24.50855 4.89709   1.000 12.00672 ? 1535 LEU A CD1  1 
ATOM   1091 C  CD2  . LEU A 1 76  ? -14.41908 -24.75039 5.28632   1.000 13.04895 ? 1535 LEU A CD2  1 
ATOM   1092 H  H    . LEU A 1 76  ? -13.29931 -23.03818 1.22810   1.000 12.30745 ? 1535 LEU A H    1 
ATOM   1093 H  HA   . LEU A 1 76  ? -15.36048 -23.56953 2.89024   1.000 12.30430 ? 1535 LEU A HA   1 
ATOM   1094 H  HB2  . LEU A 1 76  ? -12.74014 -22.68992 3.28589   1.000 12.93595 ? 1535 LEU A HB2  1 
ATOM   1095 H  HB3  . LEU A 1 76  ? -13.81891 -22.38817 4.41310   1.000 12.93595 ? 1535 LEU A HB3  1 
ATOM   1096 H  HG   . LEU A 1 76  ? -13.41727 -24.98995 3.52583   1.000 14.32875 ? 1535 LEU A HG   1 
ATOM   1097 H  HD11 . LEU A 1 76  ? -11.87837 -25.40562 5.25347   1.000 14.41086 ? 1535 LEU A HD11 1 
ATOM   1098 H  HD12 . LEU A 1 76  ? -11.30018 -24.34874 4.21799   1.000 14.41086 ? 1535 LEU A HD12 1 
ATOM   1099 H  HD13 . LEU A 1 76  ? -11.88523 -23.85781 5.61091   1.000 14.41086 ? 1535 LEU A HD13 1 
ATOM   1100 H  HD21 . LEU A 1 76  ? -14.24226 -25.64836 5.60772   1.000 15.66154 ? 1535 LEU A HD21 1 
ATOM   1101 H  HD22 . LEU A 1 76  ? -14.38887 -24.12267 6.02520   1.000 15.66154 ? 1535 LEU A HD22 1 
ATOM   1102 H  HD23 . LEU A 1 76  ? -15.28950 -24.71724 4.85950   1.000 15.66154 ? 1535 LEU A HD23 1 
ATOM   1103 N  N    . GLY A 1 77  ? -16.21713 -21.23132 3.37258   1.000 10.36705 ? 1536 GLY A N    1 
ATOM   1104 C  CA   . GLY A 1 77  ? -16.78476 -19.89400 3.45559   1.000 10.76973 ? 1536 GLY A CA   1 
ATOM   1105 C  C    . GLY A 1 77  ? -16.44024 -19.19378 4.75942   1.000 10.67762 ? 1536 GLY A C    1 
ATOM   1106 O  O    . GLY A 1 77  ? -16.48792 -19.79277 5.82936   1.000 11.79354 ? 1536 GLY A O    1 
ATOM   1107 H  H    . GLY A 1 77  ? -16.58574 -21.79918 3.90293   1.000 12.44326 ? 1536 GLY A H    1 
ATOM   1108 H  HA2  . GLY A 1 77  ? -16.44675 -19.35594 2.72268   1.000 12.92648 ? 1536 GLY A HA2  1 
ATOM   1109 H  HA3  . GLY A 1 77  ? -17.75064 -19.95058 3.38656   1.000 12.92648 ? 1536 GLY A HA3  1 
ATOM   1110 N  N    . ALA A 1 78  ? -16.16037 -17.89548 4.66535   1.000 9.94858  ? 1537 ALA A N    1 
ATOM   1111 C  CA   . ALA A 1 78  ? -15.90923 -17.08619 5.84365   1.000 10.96186 ? 1537 ALA A CA   1 
ATOM   1112 C  C    . ALA A 1 78  ? -17.22633 -16.69477 6.50109   1.000 11.64616 ? 1537 ALA A C    1 
ATOM   1113 O  O    . ALA A 1 78  ? -18.17769 -16.29793 5.81552   1.000 12.61206 ? 1537 ALA A O    1 
ATOM   1114 C  CB   . ALA A 1 78  ? -15.16700 -15.82039 5.41634   1.000 11.14609 ? 1537 ALA A CB   1 
ATOM   1115 H  H    . ALA A 1 78  ? -16.11081 -17.46154 3.92451   1.000 11.94110 ? 1537 ALA A H    1 
ATOM   1116 H  HA   . ALA A 1 78  ? -15.37773 -17.57933 6.48803   1.000 13.15703 ? 1537 ALA A HA   1 
ATOM   1117 H  HB1  . ALA A 1 78  ? -15.04314 -15.25015 6.19118   1.000 13.37811 ? 1537 ALA A HB1  1 
ATOM   1118 H  HB2  . ALA A 1 78  ? -14.30503 -16.06906 5.04746   1.000 13.37811 ? 1537 ALA A HB2  1 
ATOM   1119 H  HB3  . ALA A 1 78  ? -15.69273 -15.35730 4.74548   1.000 13.37811 ? 1537 ALA A HB3  1 
ATOM   1120 N  N    . ALA A 1 79  ? -17.27782 -16.78747 7.82393   1.000 13.59376 ? 1538 ALA A N    1 
ATOM   1121 C  CA   . ALA A 1 79  ? -18.45621 -16.42686 8.58927   1.000 17.79162 ? 1538 ALA A CA   1 
ATOM   1122 C  C    . ALA A 1 79  ? -18.06618 -15.42119 9.65455   1.000 15.00708 ? 1538 ALA A C    1 
ATOM   1123 O  O    . ALA A 1 79  ? -16.88118 -15.16608 9.89968   1.000 13.68588 ? 1538 ALA A O    1 
ATOM   1124 C  CB   . ALA A 1 79  ? -19.05107 -17.63727 9.33881   1.000 24.62401 ? 1538 ALA A CB   1 
ATOM   1125 H  H    . ALA A 1 79  ? -16.62435 -17.06401 8.30984   1.000 16.31531 ? 1538 ALA A H    1 
ATOM   1126 H  HA   . ALA A 1 79  ? -19.10663 -16.05656 7.97224   1.000 21.35275 ? 1538 ALA A HA   1 
ATOM   1127 H  HB1  . ALA A 1 79  ? -19.84134 -17.35146 9.82326   1.000 29.55161 ? 1538 ALA A HB1  1 
ATOM   1128 H  HB2  . ALA A 1 79  ? -19.28793 -18.32248 8.69439   1.000 29.55161 ? 1538 ALA A HB2  1 
ATOM   1129 H  HB3  . ALA A 1 79  ? -18.38921 -17.98106 9.95900   1.000 29.55161 ? 1538 ALA A HB3  1 
ATOM   1130 N  N    . SER A 1 80  ? -19.07602 -14.90112 10.35048  1.000 15.36502 ? 1539 SER A N    1 
ATOM   1131 C  CA   . SER A 1 80  ? -18.83671 -14.01924 11.48225  1.000 16.93890 ? 1539 SER A CA   1 
ATOM   1132 C  C    . SER A 1 80  ? -18.28758 -14.73965 12.70155  1.000 18.17325 ? 1539 SER A C    1 
ATOM   1133 O  O    . SER A 1 80  ? -17.94699 -14.07275 13.68686  1.000 19.41814 ? 1539 SER A O    1 
ATOM   1134 C  CB   . SER A 1 80  ? -20.14181 -13.29194 11.84363  1.000 18.49434 ? 1539 SER A CB   1 
ATOM   1135 O  OG   . SER A 1 80  ? -21.09965 -14.20411 12.35055  1.000 20.00242 ? 1539 SER A OG   1 
ATOM   1136 H  H    . SER A 1 80  ? -19.90754 -15.04532 10.18502  1.000 18.44082 ? 1539 SER A H    1 
ATOM   1137 H  HA   . SER A 1 80  ? -18.17666 -13.35594 11.22679  1.000 20.32947 ? 1539 SER A HA   1 
ATOM   1138 H  HB2  . SER A 1 80  ? -19.95395 -12.62226 12.51975  1.000 22.19601 ? 1539 SER A HB2  1 
ATOM   1139 H  HB3  . SER A 1 80  ? -20.49882 -12.86839 11.04735  1.000 22.19601 ? 1539 SER A HB3  1 
ATOM   1140 H  HG   . SER A 1 80  ? -21.80020 -13.79430 12.56706  1.000 24.00570 ? 1539 SER A HG   1 
ATOM   1141 N  N    . GLU A 1 81  ? -18.17831 -16.06828 12.66687  1.000 18.62857 ? 1540 GLU A N    1 
ATOM   1142 C  CA   A GLU A 1 81  ? -17.75760 -16.81010 13.84177  0.503 19.34181 ? 1540 GLU A CA   1 
ATOM   1143 C  CA   B GLU A 1 81  ? -17.77270 -16.82901 13.83468  0.497 18.88386 ? 1540 GLU A CA   1 
ATOM   1144 C  C    . GLU A 1 81  ? -16.54000 -17.68775 13.61652  1.000 18.22589 ? 1540 GLU A C    1 
ATOM   1145 O  O    . GLU A 1 81  ? -15.97183 -18.18080 14.60262  1.000 20.08137 ? 1540 GLU A O    1 
ATOM   1146 C  CB   A GLU A 1 81  ? -18.91263 -17.68194 14.37239  0.503 21.44733 ? 1540 GLU A CB   1 
ATOM   1147 C  CB   B GLU A 1 81  ? -18.91129 -17.75901 14.28739  0.497 20.04190 ? 1540 GLU A CB   1 
ATOM   1148 C  CG   A GLU A 1 81  ? -19.87950 -16.92063 15.28314  0.503 23.76866 ? 1540 GLU A CG   1 
ATOM   1149 C  CG   B GLU A 1 81  ? -20.24974 -17.06267 14.47565  0.497 21.43943 ? 1540 GLU A CG   1 
ATOM   1150 C  CD   A GLU A 1 81  ? -21.29603 -17.48429 15.29301  0.503 25.96366 ? 1540 GLU A CD   1 
ATOM   1151 C  CD   B GLU A 1 81  ? -20.14749 -15.82073 15.34699  0.497 23.07384 ? 1540 GLU A CD   1 
ATOM   1152 O  OE1  A GLU A 1 81  ? -21.55237 -18.51069 14.63611  0.503 26.61637 ? 1540 GLU A OE1  1 
ATOM   1153 O  OE1  B GLU A 1 81  ? -19.50749 -15.90936 16.41799  0.497 23.50810 ? 1540 GLU A OE1  1 
ATOM   1154 O  OE2  A GLU A 1 81  ? -22.16683 -16.87386 15.94391  0.503 27.27434 ? 1540 GLU A OE2  1 
ATOM   1155 O  OE2  B GLU A 1 81  ? -20.70838 -14.76554 14.97285  0.497 23.93973 ? 1540 GLU A OE2  1 
ATOM   1156 H  H    A GLU A 1 81  ? -18.34249 -16.55403 11.97645  0.503 22.35708 ? 1540 GLU A H    1 
ATOM   1157 H  H    B GLU A 1 81  ? -18.33594 -16.54929 11.97161  0.497 22.35708 ? 1540 GLU A H    1 
ATOM   1158 H  HA   A GLU A 1 81  ? -17.52837 -16.17183 14.53528  0.503 23.21297 ? 1540 GLU A HA   1 
ATOM   1159 H  HA   B GLU A 1 81  ? -17.58083 -16.19868 14.54656  0.497 22.66343 ? 1540 GLU A HA   1 
ATOM   1160 H  HB2  A GLU A 1 81  ? -19.41943 -18.02295 13.61889  0.503 25.73959 ? 1540 GLU A HB2  1 
ATOM   1161 H  HB2  B GLU A 1 81  ? -19.03130 -18.45043 13.61774  0.497 24.05307 ? 1540 GLU A HB2  1 
ATOM   1162 H  HB3  A GLU A 1 81  ? -18.54051 -18.41832 14.88245  0.503 25.73959 ? 1540 GLU A HB3  1 
ATOM   1163 H  HB3  B GLU A 1 81  ? -18.66583 -18.15856 15.13651  0.497 24.05307 ? 1540 GLU A HB3  1 
ATOM   1164 H  HG2  A GLU A 1 81  ? -19.54267 -16.95431 16.19216  0.503 28.52519 ? 1540 GLU A HG2  1 
ATOM   1165 H  HG2  B GLU A 1 81  ? -20.59114 -16.79370 13.60846  0.497 25.73012 ? 1540 GLU A HG2  1 
ATOM   1166 H  HG3  A GLU A 1 81  ? -19.93086 -15.99991 14.98226  0.503 28.52519 ? 1540 GLU A HG3  1 
ATOM   1167 H  HG3  B GLU A 1 81  ? -20.86900 -17.67696 14.90000  0.497 25.73012 ? 1540 GLU A HG3  1 
ATOM   1168 N  N    . ASN A 1 82  ? -16.10194 -17.88546 12.37282  1.000 15.80981 ? 1541 ASN A N    1 
ATOM   1169 C  CA   . ASN A 1 82  ? -15.12266 -18.93481 12.13709  1.000 14.67020 ? 1541 ASN A CA   1 
ATOM   1170 C  C    . ASN A 1 82  ? -13.69659 -18.46400 11.87945  1.000 14.19120 ? 1541 ASN A C    1 
ATOM   1171 O  O    . ASN A 1 82  ? -12.81930 -19.31860 11.71204  1.000 15.06235 ? 1541 ASN A O    1 
ATOM   1172 C  CB   . ASN A 1 82  ? -15.60071 -19.91052 11.04793  1.000 14.19383 ? 1541 ASN A CB   1 
ATOM   1173 C  CG   . ASN A 1 82  ? -15.70422 -19.28954 9.67883   1.000 13.29898 ? 1541 ASN A CG   1 
ATOM   1174 O  OD1  . ASN A 1 82  ? -15.38749 -18.11700 9.48051   1.000 13.34899 ? 1541 ASN A OD1  1 
ATOM   1175 N  ND2  . ASN A 1 82  ? -16.18039 -20.05749 8.72326   1.000 12.98052 ? 1541 ASN A ND2  1 
ATOM   1176 H  H    . ASN A 1 82  ? -16.34988 -17.44019 11.68010  1.000 18.97457 ? 1541 ASN A H    1 
ATOM   1177 H  HA   . ASN A 1 82  ? -15.06595 -19.44491 12.96018  1.000 17.60704 ? 1541 ASN A HA   1 
ATOM   1178 H  HB2  . ASN A 1 82  ? -14.97254 -20.64750 10.99150  1.000 17.03539 ? 1541 ASN A HB2  1 
ATOM   1179 H  HB3  . ASN A 1 82  ? -16.47983 -20.24169 11.28952  1.000 17.03539 ? 1541 ASN A HB3  1 
ATOM   1180 H  HD21 . ASN A 1 82  ? -16.25942 -19.75025 7.92391   1.000 15.57943 ? 1541 ASN A HD21 1 
ATOM   1181 H  HD22 . ASN A 1 82  ? -16.41274 -20.86692 8.89774   1.000 15.57943 ? 1541 ASN A HD22 1 
ATOM   1182 N  N    . ALA A 1 83  ? -13.40333 -17.16286 11.90654  1.000 14.12803 ? 1542 ALA A N    1 
ATOM   1183 C  CA   . ALA A 1 83  ? -12.01374 -16.75490 11.72850  1.000 14.29121 ? 1542 ALA A CA   1 
ATOM   1184 C  C    . ALA A 1 83  ? -11.16778 -17.35481 12.84680  1.000 14.83075 ? 1542 ALA A C    1 
ATOM   1185 O  O    . ALA A 1 83  ? -11.54424 -17.31461 14.02310  1.000 16.13879 ? 1542 ALA A O    1 
ATOM   1186 C  CB   . ALA A 1 83  ? -11.89112 -15.23733 11.73652  1.000 15.22290 ? 1542 ALA A CB   1 
ATOM   1187 H  H    . ALA A 1 83  ? -13.96813 -16.52463 12.02169  1.000 16.95643 ? 1542 ALA A H    1 
ATOM   1188 H  HA   . ALA A 1 83  ? -11.68874 -17.06974 10.87051  1.000 17.15225 ? 1542 ALA A HA   1 
ATOM   1189 H  HB1  . ALA A 1 83  ? -10.95713 -14.99543 11.63622  1.000 18.27027 ? 1542 ALA A HB1  1 
ATOM   1190 H  HB2  . ALA A 1 83  ? -12.40764 -14.87486 10.99982  1.000 18.27027 ? 1542 ALA A HB2  1 
ATOM   1191 H  HB3  . ALA A 1 83  ? -12.23227 -14.89738 12.57851  1.000 18.27027 ? 1542 ALA A HB3  1 
ATOM   1192 N  N    . GLY A 1 84  ? -10.03292 -17.92686 12.46887  1.000 15.96509 ? 1543 GLY A N    1 
ATOM   1193 C  CA   . GLY A 1 84  ? -9.13832  -18.53952 13.42141  1.000 17.57055 ? 1543 GLY A CA   1 
ATOM   1194 C  C    . GLY A 1 84  ? -9.47964  -19.95713 13.80747  1.000 17.85479 ? 1543 GLY A C    1 
ATOM   1195 O  O    . GLY A 1 84  ? -8.80184  -20.51970 14.66991  1.000 19.24969 ? 1543 GLY A O    1 
ATOM   1196 H  H    . GLY A 1 84  ? -9.76041  -17.97063 11.65436  1.000 19.16091 ? 1543 GLY A H    1 
ATOM   1197 H  HA2  . GLY A 1 84  ? -8.24391  -18.54439 13.04603  1.000 21.08745 ? 1543 GLY A HA2  1 
ATOM   1198 H  HA3  . GLY A 1 84  ? -9.13784  -18.00627 14.23169  1.000 21.08745 ? 1543 GLY A HA3  1 
ATOM   1199 N  N    . THR A 1 85  ? -10.51172 -20.54834 13.20694  1.000 16.33356 ? 1544 THR A N    1 
ATOM   1200 C  CA   . THR A 1 85  ? -10.91918 -21.90451 13.53218  1.000 16.56253 ? 1544 THR A CA   1 
ATOM   1201 C  C    . THR A 1 85  ? -10.69801 -22.88806 12.39743  1.000 16.63359 ? 1544 THR A C    1 
ATOM   1202 O  O    . THR A 1 85  ? -10.94063 -24.08902 12.58781  1.000 18.51276 ? 1544 THR A O    1 
ATOM   1203 C  CB   . THR A 1 85  ? -12.41205 -21.96048 13.89979  1.000 16.95468 ? 1544 THR A CB   1 
ATOM   1204 O  OG1  . THR A 1 85  ? -13.20376 -21.79996 12.71479  1.000 16.14406 ? 1544 THR A OG1  1 
ATOM   1205 C  CG2  . THR A 1 85  ? -12.78528 -20.90350 14.90938  1.000 17.96533 ? 1544 THR A CG2  1 
ATOM   1206 H  H    . THR A 1 85  ? -10.99486 -20.17598 12.60071  1.000 19.60307 ? 1544 THR A H    1 
ATOM   1207 H  HA   . THR A 1 85  ? -10.40150 -22.18438 14.30327  1.000 19.87784 ? 1544 THR A HA   1 
ATOM   1208 H  HB   . THR A 1 85  ? -12.60020 -22.82107 14.30585  1.000 20.34842 ? 1544 THR A HB   1 
ATOM   1209 H  HG1  . THR A 1 85  ? -13.04078 -21.05675 12.35888  1.000 19.37567 ? 1544 THR A HG1  1 
ATOM   1210 H  HG21 . THR A 1 85  ? -13.70158 -21.03176 15.20064  1.000 21.56119 ? 1544 THR A HG21 1 
ATOM   1211 H  HG22 . THR A 1 85  ? -12.19917 -20.95936 15.68026  1.000 21.56119 ? 1544 THR A HG22 1 
ATOM   1212 H  HG23 . THR A 1 85  ? -12.70132 -20.02204 14.51330  1.000 21.56119 ? 1544 THR A HG23 1 
ATOM   1213 N  N    . LEU A 1 86  ? -10.29058 -22.41939 11.21926  1.000 15.37555 ? 1545 LEU A N    1 
ATOM   1214 C  CA   . LEU A 1 86  ? -10.24109 -23.24375 10.02432  1.000 14.84127 ? 1545 LEU A CA   1 
ATOM   1215 C  C    . LEU A 1 86  ? -8.84399  -23.76834 9.71063   1.000 15.64400 ? 1545 LEU A C    1 
ATOM   1216 O  O    . LEU A 1 86  ? -8.65282  -24.40142 8.66996   1.000 15.68085 ? 1545 LEU A O    1 
ATOM   1217 C  CB   . LEU A 1 86  ? -10.76601 -22.45891 8.81786   1.000 14.42543 ? 1545 LEU A CB   1 
ATOM   1218 C  CG   . LEU A 1 86  ? -12.19834 -21.91228 8.94445   1.000 14.83338 ? 1545 LEU A CG   1 
ATOM   1219 C  CD1  . LEU A 1 86  ? -12.54004 -21.08594 7.73715   1.000 15.35712 ? 1545 LEU A CD1  1 
ATOM   1220 C  CD2  . LEU A 1 86  ? -13.18484 -23.04311 9.13131   1.000 15.61505 ? 1545 LEU A CD2  1 
ATOM   1221 H  H    . LEU A 1 86  ? -10.03329 -21.60919 11.08897  1.000 18.45346 ? 1545 LEU A H    1 
ATOM   1222 H  HA   . LEU A 1 86  ? -10.81897 -24.00874 10.17180  1.000 17.81233 ? 1545 LEU A HA   1 
ATOM   1223 H  HB2  . LEU A 1 86  ? -10.18009 -21.69971 8.67216   1.000 17.31332 ? 1545 LEU A HB2  1 
ATOM   1224 H  HB3  . LEU A 1 86  ? -10.74874 -23.04448 8.04475   1.000 17.31332 ? 1545 LEU A HB3  1 
ATOM   1225 H  HG   . LEU A 1 86  ? -12.26066 -21.34180 9.72647   1.000 17.80285 ? 1545 LEU A HG   1 
ATOM   1226 H  HD11 . LEU A 1 86  ? -13.44669 -20.75342 7.82836   1.000 18.43135 ? 1545 LEU A HD11 1 
ATOM   1227 H  HD12 . LEU A 1 86  ? -11.91959 -20.34273 7.67726   1.000 18.43135 ? 1545 LEU A HD12 1 
ATOM   1228 H  HD13 . LEU A 1 86  ? -12.46930 -21.64058 6.94452   1.000 18.43135 ? 1545 LEU A HD13 1 
ATOM   1229 H  HD21 . LEU A 1 86  ? -14.08590 -22.68673 9.08674   1.000 18.74086 ? 1545 LEU A HD21 1 
ATOM   1230 H  HD22 . LEU A 1 86  ? -13.05260 -23.69712 8.42727   1.000 18.74086 ? 1545 LEU A HD22 1 
ATOM   1231 H  HD23 . LEU A 1 86  ? -13.03406 -23.45392 9.99699   1.000 18.74086 ? 1545 LEU A HD23 1 
ATOM   1232 N  N    . GLY A 1 87  ? -7.87406  -23.54218 10.58893  1.000 16.84415 ? 1546 GLY A N    1 
ATOM   1233 C  CA   . GLY A 1 87  ? -6.49249  -23.83445 10.22546  1.000 18.20483 ? 1546 GLY A CA   1 
ATOM   1234 C  C    . GLY A 1 87  ? -6.20675  -25.29631 9.93976   1.000 18.90492 ? 1546 GLY A C    1 
ATOM   1235 O  O    . GLY A 1 87  ? -5.35755  -25.61298 9.09744   1.000 20.05769 ? 1546 GLY A O    1 
ATOM   1236 H  H    . GLY A 1 87  ? -7.98464  -23.22810 11.38185  1.000 20.21577 ? 1546 GLY A H    1 
ATOM   1237 H  HA2  . GLY A 1 87  ? -6.26575  -23.32786 9.42994   1.000 21.84860 ? 1546 GLY A HA2  1 
ATOM   1238 H  HA3  . GLY A 1 87  ? -5.91359  -23.55658 10.95248  1.000 21.84860 ? 1546 GLY A HA3  1 
ATOM   1239 N  N    . THR A 1 88  ? -6.88307  -26.20868 10.63242  1.000 19.66817 ? 1547 THR A N    1 
ATOM   1240 C  CA   . THR A 1 88  ? -6.60477  -27.62335 10.42574  1.000 21.37100 ? 1547 THR A CA   1 
ATOM   1241 C  C    . THR A 1 88  ? -7.14257  -28.12403 9.09151   1.000 19.89451 ? 1547 THR A C    1 
ATOM   1242 O  O    . THR A 1 88  ? -6.55805  -29.04556 8.50366   1.000 21.53944 ? 1547 THR A O    1 
ATOM   1243 C  CB   . THR A 1 88  ? -7.15354  -28.44055 11.59529  1.000 24.80036 ? 1547 THR A CB   1 
ATOM   1244 O  OG1  . THR A 1 88  ? -8.58098  -28.45664 11.52955  1.000 27.49015 ? 1547 THR A OG1  1 
ATOM   1245 C  CG2  . THR A 1 88  ? -6.71292  -27.86969 12.92299  1.000 25.51097 ? 1547 THR A CG2  1 
ATOM   1246 H  H    . THR A 1 88  ? -7.49334  -26.03842 11.21396  1.000 23.60460 ? 1547 THR A H    1 
ATOM   1247 H  HA   . THR A 1 88  ? -5.64401  -27.75558 10.40692  1.000 25.64800 ? 1547 THR A HA   1 
ATOM   1248 H  HB   . THR A 1 88  ? -6.81116  -29.34645 11.54024  1.000 29.76323 ? 1547 THR A HB   1 
ATOM   1249 H  HG1  . THR A 1 88  ? -8.89171  -28.93292 12.14777  1.000 32.99098 ? 1547 THR A HG1  1 
ATOM   1250 H  HG21 . THR A 1 88  ? -7.06453  -28.40852 13.64889  1.000 30.61596 ? 1547 THR A HG21 1 
ATOM   1251 H  HG22 . THR A 1 88  ? -5.74441  -27.86315 12.97630  1.000 30.61596 ? 1547 THR A HG22 1 
ATOM   1252 H  HG23 . THR A 1 88  ? -7.03958  -26.96134 13.01837  1.000 30.61596 ? 1547 THR A HG23 1 
ATOM   1253 N  N    . VAL A 1 89  ? -8.22472  -27.53102 8.58454   1.000 16.86257 ? 1548 VAL A N    1 
ATOM   1254 C  CA   . VAL A 1 89  ? -8.84246  -27.97844 7.34108   1.000 16.05984 ? 1548 VAL A CA   1 
ATOM   1255 C  C    . VAL A 1 89  ? -8.57463  -27.04659 6.16597   1.000 13.99380 ? 1548 VAL A C    1 
ATOM   1256 O  O    . VAL A 1 89  ? -8.91345  -27.40079 5.02423   1.000 14.15961 ? 1548 VAL A O    1 
ATOM   1257 C  CB   . VAL A 1 89  ? -10.36200 -28.21176 7.50047   1.000 17.08101 ? 1548 VAL A CB   1 
ATOM   1258 C  CG1  . VAL A 1 89  ? -10.62787 -29.32982 8.48560   1.000 17.91532 ? 1548 VAL A CG1  1 
ATOM   1259 C  CG2  . VAL A 1 89  ? -11.08574 -26.93663 7.91509   1.000 16.36251 ? 1548 VAL A CG2  1 
ATOM   1260 H  H    . VAL A 1 89  ? -8.62201  -26.86050 8.94809   1.000 20.23788 ? 1548 VAL A H    1 
ATOM   1261 H  HA   . VAL A 1 89  ? -8.44676  -28.83518 7.11675   1.000 19.27460 ? 1548 VAL A HA   1 
ATOM   1262 H  HB   . VAL A 1 89  ? -10.71919 -28.47523 6.63797   1.000 20.50001 ? 1548 VAL A HB   1 
ATOM   1263 H  HG11 . VAL A 1 89  ? -11.58558 -29.46522 8.55870   1.000 21.50119 ? 1548 VAL A HG11 1 
ATOM   1264 H  HG12 . VAL A 1 89  ? -10.20265 -30.14069 8.16532   1.000 21.50119 ? 1548 VAL A HG12 1 
ATOM   1265 H  HG13 . VAL A 1 89  ? -10.26177 -29.08333 9.34938   1.000 21.50119 ? 1548 VAL A HG13 1 
ATOM   1266 H  HG21 . VAL A 1 89  ? -12.03439 -27.12322 7.99355   1.000 19.63781 ? 1548 VAL A HG21 1 
ATOM   1267 H  HG22 . VAL A 1 89  ? -10.73559 -26.63820 8.76904   1.000 19.63781 ? 1548 VAL A HG22 1 
ATOM   1268 H  HG23 . VAL A 1 89  ? -10.93726 -26.25563 7.24049   1.000 19.63781 ? 1548 VAL A HG23 1 
ATOM   1269 N  N    . ALA A 1 90  ? -7.95336  -25.88356 6.39567   1.000 13.10159 ? 1549 ALA A N    1 
ATOM   1270 C  CA   . ALA A 1 90  ? -7.81648  -24.88820 5.33888   1.000 12.94368 ? 1549 ALA A CA   1 
ATOM   1271 C  C    . ALA A 1 90  ? -7.14582  -25.45277 4.09061   1.000 12.61206 ? 1549 ALA A C    1 
ATOM   1272 O  O    . ALA A 1 90  ? -7.57785  -25.17288 2.97014   1.000 12.89104 ? 1549 ALA A O    1 
ATOM   1273 C  CB   . ALA A 1 90  ? -7.06164  -23.66728 5.87536   1.000 12.97789 ? 1549 ALA A CB   1 
ATOM   1274 H  H    . ALA A 1 90  ? -7.60718  -25.65233 7.14819   1.000 15.72471 ? 1549 ALA A H    1 
ATOM   1275 H  HA   . ALA A 1 90  ? -8.70281  -24.60138 5.06857   1.000 15.53521 ? 1549 ALA A HA   1 
ATOM   1276 H  HB1  . ALA A 1 90  ? -6.98377  -23.00821 5.16792   1.000 15.57627 ? 1549 ALA A HB1  1 
ATOM   1277 H  HB2  . ALA A 1 90  ? -7.55519  -23.29400 6.62234   1.000 15.57627 ? 1549 ALA A HB2  1 
ATOM   1278 H  HB3  . ALA A 1 90  ? -6.17929  -23.94480 6.16749   1.000 15.57627 ? 1549 ALA A HB3  1 
ATOM   1279 N  N    . GLY A 1 91  ? -6.07215  -26.23127 4.25311   1.000 12.95157 ? 1550 GLY A N    1 
ATOM   1280 C  CA   . GLY A 1 91  ? -5.35554  -26.69747 3.07736   1.000 12.76997 ? 1550 GLY A CA   1 
ATOM   1281 C  C    . GLY A 1 91  ? -6.09095  -27.73708 2.26276   1.000 12.65417 ? 1550 GLY A C    1 
ATOM   1282 O  O    . GLY A 1 91  ? -5.67666  -28.02990 1.13370   1.000 13.56743 ? 1550 GLY A O    1 
ATOM   1283 H  H    . GLY A 1 91  ? -5.75444  -26.49108 5.00886   1.000 15.54468 ? 1550 GLY A H    1 
ATOM   1284 H  HA2  . GLY A 1 91  ? -5.17789  -25.93890 2.49950   1.000 15.32676 ? 1550 GLY A HA2  1 
ATOM   1285 H  HA3  . GLY A 1 91  ? -4.51179  -27.08396 3.35951   1.000 15.32676 ? 1550 GLY A HA3  1 
ATOM   1286 N  N    . SER A 1 92  ? -7.17208  -28.28732 2.80109   1.000 12.48310 ? 1551 SER A N    1 
ATOM   1287 C  CA   A SER A 1 92  ? -7.97444  -29.25478 2.07045   0.596 12.73576 ? 1551 SER A CA   1 
ATOM   1288 C  CA   B SER A 1 92  ? -7.99902  -29.25250 2.09457   0.404 12.49099 ? 1551 SER A CA   1 
ATOM   1289 C  C    . SER A 1 92  ? -9.01685  -28.59586 1.18052   1.000 12.39624 ? 1551 SER A C    1 
ATOM   1290 O  O    . SER A 1 92  ? -9.65653  -29.28914 0.38723   1.000 12.63838 ? 1551 SER A O    1 
ATOM   1291 C  CB   A SER A 1 92  ? -8.63211  -30.23423 3.05248   0.596 13.83852 ? 1551 SER A CB   1 
ATOM   1292 C  CB   B SER A 1 92  ? -8.75479  -30.11880 3.10512   0.404 12.93315 ? 1551 SER A CB   1 
ATOM   1293 O  OG   A SER A 1 92  ? -9.76092  -29.66532 3.68183   0.596 14.57019 ? 1551 SER A OG   1 
ATOM   1294 O  OG   B SER A 1 92  ? -7.84779  -30.86117 3.88840   0.404 13.19371 ? 1551 SER A OG   1 
ATOM   1295 H  H    A SER A 1 92  ? -7.46187  -28.11481 3.59221   0.596 14.98251 ? 1551 SER A H    1 
ATOM   1296 H  H    B SER A 1 92  ? -7.45431  -28.11313 3.59457   0.404 14.98251 ? 1551 SER A H    1 
ATOM   1297 H  HA   A SER A 1 92  ? -7.40246  -29.78199 1.49098   0.596 15.28571 ? 1551 SER A HA   1 
ATOM   1298 H  HA   B SER A 1 92  ? -7.42149  -29.81909 1.55947   0.404 14.99199 ? 1551 SER A HA   1 
ATOM   1299 H  HB2  A SER A 1 92  ? -8.91195  -31.02457 2.56468   0.596 16.60902 ? 1551 SER A HB2  1 
ATOM   1300 H  HB2  B SER A 1 92  ? -9.28036  -29.54561 3.68489   0.404 15.52258 ? 1551 SER A HB2  1 
ATOM   1301 H  HB3  A SER A 1 92  ? -7.98437  -30.47626 3.73275   0.596 16.60902 ? 1551 SER A HB3  1 
ATOM   1302 H  HB3  B SER A 1 92  ? -9.33662  -30.73032 2.62720   0.404 15.52258 ? 1551 SER A HB3  1 
ATOM   1303 H  HG   A SER A 1 92  ? -9.53617  -28.97661 4.10700   0.596 17.48702 ? 1551 SER A HG   1 
ATOM   1304 H  HG   B SER A 1 92  ? -7.33955  -30.34153 4.30943   0.404 15.83525 ? 1551 SER A HG   1 
ATOM   1305 N  N    . ALA A 1 93  ? -9.18325  -27.28522 1.28027   1.000 12.07778 ? 1552 ALA A N    1 
ATOM   1306 C  CA   . ALA A 1 93  ? -10.18096 -26.54490 0.52732   1.000 11.73564 ? 1552 ALA A CA   1 
ATOM   1307 C  C    . ALA A 1 93  ? -9.57099  -25.90735 -0.71337  1.000 11.55404 ? 1552 ALA A C    1 
ATOM   1308 O  O    . ALA A 1 93  ? -8.35931  -25.70001 -0.80378  1.000 12.29360 ? 1552 ALA A O    1 
ATOM   1309 C  CB   . ALA A 1 93  ? -10.78000 -25.46327 1.42871   1.000 12.34624 ? 1552 ALA A CB   1 
ATOM   1310 H  H    . ALA A 1 93  ? -8.71202  -26.78493 1.79723   1.000 14.49614 ? 1552 ALA A H    1 
ATOM   1311 H  HA   . ALA A 1 93  ? -10.88184 -27.14435 0.22678   1.000 14.08556 ? 1552 ALA A HA   1 
ATOM   1312 H  HB1  . ALA A 1 93  ? -11.46211 -24.98236 0.93440   1.000 14.81828 ? 1552 ALA A HB1  1 
ATOM   1313 H  HB2  . ALA A 1 93  ? -11.17236 -25.88446 2.20945   1.000 14.81828 ? 1552 ALA A HB2  1 
ATOM   1314 H  HB3  . ALA A 1 93  ? -10.07644 -24.85328 1.70040   1.000 14.81828 ? 1552 ALA A HB3  1 
ATOM   1315 N  N    . ALA A 1 94  ? -10.43407 -25.59360 -1.67977  1.000 10.98292 ? 1553 ALA A N    1 
ATOM   1316 C  CA   . ALA A 1 94  ? -10.01547 -24.77843 -2.82122  1.000 10.55392 ? 1553 ALA A CA   1 
ATOM   1317 C  C    . ALA A 1 94  ? -9.38939  -23.46579 -2.34773  1.000 10.10123 ? 1553 ALA A C    1 
ATOM   1318 O  O    . ALA A 1 94  ? -8.38910  -23.00093 -2.90682  1.000 11.26716 ? 1553 ALA A O    1 
ATOM   1319 C  CB   . ALA A 1 94  ? -11.20840 -24.49383 -3.73519  1.000 11.01187 ? 1553 ALA A CB   1 
ATOM   1320 H  H    . ALA A 1 94  ? -11.25876 -25.83670 -1.69952  1.000 13.18230 ? 1553 ALA A H    1 
ATOM   1321 H  HA   . ALA A 1 94  ? -9.35666  -25.27108 -3.33519  1.000 12.66750 ? 1553 ALA A HA   1 
ATOM   1322 H  HB1  . ALA A 1 94  ? -10.90917 -23.96064 -4.48822  1.000 13.21704 ? 1553 ALA A HB1  1 
ATOM   1323 H  HB2  . ALA A 1 94  ? -11.57290 -25.33578 -4.05010  1.000 13.21704 ? 1553 ALA A HB2  1 
ATOM   1324 H  HB3  . ALA A 1 94  ? -11.88206 -24.00880 -3.23336  1.000 13.21704 ? 1553 ALA A HB3  1 
ATOM   1325 N  N    . GLY A 1 95  ? -9.97813  -22.87689 -1.31933  1.000 10.22493 ? 1554 GLY A N    1 
ATOM   1326 C  CA   . GLY A 1 95  ? -9.60606  -21.56951 -0.81660  1.000 10.50128 ? 1554 GLY A CA   1 
ATOM   1327 C  C    . GLY A 1 95  ? -10.70271 -21.12019 0.13258   1.000 10.05123 ? 1554 GLY A C    1 
ATOM   1328 O  O    . GLY A 1 95  ? -11.59361 -21.90089 0.47778   1.000 10.36968 ? 1554 GLY A O    1 
ATOM   1329 H  H    . GLY A 1 95  ? -10.62489 -23.22992 -0.87585  1.000 12.27271 ? 1554 GLY A H    1 
ATOM   1330 H  HA2  . GLY A 1 95  ? -8.76157  -21.61468 -0.34152  1.000 12.60433 ? 1554 GLY A HA2  1 
ATOM   1331 H  HA3  . GLY A 1 95  ? -9.52486  -20.93453 -1.54537  1.000 12.60433 ? 1554 GLY A HA3  1 
ATOM   1332 N  N    . LEU A 1 96  ? -10.60346 -19.87434 0.57450   1.000 10.01701 ? 1555 LEU A N    1 
ATOM   1333 C  CA   . LEU A 1 96  ? -11.61583 -19.24174 1.41422   1.000 9.89331  ? 1555 LEU A CA   1 
ATOM   1334 C  C    . LEU A 1 96  ? -12.39302 -18.22542 0.58073   1.000 9.37483  ? 1555 LEU A C    1 
ATOM   1335 O  O    . LEU A 1 96  ? -11.80126 -17.35655 -0.07824  1.000 10.20124 ? 1555 LEU A O    1 
ATOM   1336 C  CB   . LEU A 1 96  ? -10.94255 -18.52361 2.57228   1.000 10.18808 ? 1555 LEU A CB   1 
ATOM   1337 C  CG   . LEU A 1 96  ? -11.87784 -17.88874 3.60101   1.000 10.63551 ? 1555 LEU A CG   1 
ATOM   1338 C  CD1  . LEU A 1 96  ? -12.69605 -18.90682 4.36900   1.000 11.26190 ? 1555 LEU A CD1  1 
ATOM   1339 C  CD2  . LEU A 1 96  ? -11.06299 -17.00410 4.55067   1.000 12.19095 ? 1555 LEU A CD2  1 
ATOM   1340 H  H    . LEU A 1 96  ? -9.93991  -19.35655 0.39787   1.000 12.02321 ? 1555 LEU A H    1 
ATOM   1341 H  HA   . LEU A 1 96  ? -12.22463 -19.90710 1.77138   1.000 11.87477 ? 1555 LEU A HA   1 
ATOM   1342 H  HB2  . LEU A 1 96  ? -10.38857 -19.16458 3.04468   1.000 12.22850 ? 1555 LEU A HB2  1 
ATOM   1343 H  HB3  . LEU A 1 96  ? -10.39126 -17.81332 2.20831   1.000 12.22850 ? 1555 LEU A HB3  1 
ATOM   1344 H  HG   . LEU A 1 96  ? -12.52489 -17.34314 3.12714   1.000 12.76541 ? 1555 LEU A HG   1 
ATOM   1345 H  HD11 . LEU A 1 96  ? -13.21436 -18.44778 5.04837   1.000 13.51707 ? 1555 LEU A HD11 1 
ATOM   1346 H  HD12 . LEU A 1 96  ? -13.28952 -19.36443 3.75315   1.000 13.51707 ? 1555 LEU A HD12 1 
ATOM   1347 H  HD13 . LEU A 1 96  ? -12.09587 -19.54483 4.78570   1.000 13.51707 ? 1555 LEU A HD13 1 
ATOM   1348 H  HD21 . LEU A 1 96  ? -11.65985 -16.61185 5.20702   1.000 14.63194 ? 1555 LEU A HD21 1 
ATOM   1349 H  HD22 . LEU A 1 96  ? -10.39505 -17.54933 4.99506   1.000 14.63194 ? 1555 LEU A HD22 1 
ATOM   1350 H  HD23 . LEU A 1 96  ? -10.63030 -16.30420 4.03703   1.000 14.63194 ? 1555 LEU A HD23 1 
HETATM 1351 N  N    . KCX A 1 97  ? -13.71863 -18.33353 0.63557   1.000 9.70381  ? 1556 KCX A N    1 
HETATM 1352 C  CA   . KCX A 1 97  ? -14.63700 -17.41326 -0.00893  1.000 9.33798  ? 1556 KCX A CA   1 
HETATM 1353 C  CB   . KCX A 1 97  ? -15.79580 -18.17656 -0.66854  1.000 9.43273  ? 1556 KCX A CB   1 
HETATM 1354 C  CG   . KCX A 1 97  ? -16.92721 -17.29752 -1.20709  1.000 10.18019 ? 1556 KCX A CG   1 
HETATM 1355 C  CD   . KCX A 1 97  ? -16.47748 -16.51024 -2.43975  1.000 10.41179 ? 1556 KCX A CD   1 
HETATM 1356 C  CE   . KCX A 1 97  ? -17.55385 -15.70861 -3.12939  1.000 10.96712 ? 1556 KCX A CE   1 
HETATM 1357 N  NZ   . KCX A 1 97  ? -18.58856 -16.58567 -3.64513  1.000 11.05924 ? 1556 KCX A NZ   1 
HETATM 1358 C  C    . KCX A 1 97  ? -15.20601 -16.39882 0.97133   1.000 8.83793  ? 1556 KCX A C    1 
HETATM 1359 O  O    . KCX A 1 97  ? -15.78776 -16.76580 1.99176   1.000 10.34073 ? 1556 KCX A O    1 
HETATM 1360 C  CX   . KCX A 1 97  ? -19.48397 -16.20091 -4.54455  1.000 10.45127 ? 1556 KCX A CX   1 
HETATM 1361 O  OQ1  . KCX A 1 97  ? -19.41838 -15.03740 -4.98938  1.000 10.21440 ? 1556 KCX A OQ1  1 
HETATM 1362 O  OQ2  . KCX A 1 97  ? -20.37536 -17.03216 -4.88346  1.000 11.30927 ? 1556 KCX A OQ2  1 
HETATM 1363 H  H    . KCX A 1 97  ? -14.12483 -18.96141 1.06027   1.000 11.64737 ? 1556 KCX A H    1 
HETATM 1364 H  HA   . KCX A 1 97  ? -14.20752 -16.99216 -0.60953  1.000 11.20837 ? 1556 KCX A HA   1 
HETATM 1365 H  HB2  . KCX A 1 97  ? -16.13388 -18.70227 -0.09249  1.000 11.32207 ? 1556 KCX A HB2  1 
HETATM 1366 H  HB3  . KCX A 1 97  ? -15.48624 -18.62238 -1.32269  1.000 11.32207 ? 1556 KCX A HB3  1 
HETATM 1367 H  HG2  . KCX A 1 97  ? -17.16493 -16.74407 -0.60735  1.000 12.21902 ? 1556 KCX A HG2  1 
HETATM 1368 H  HG3  . KCX A 1 97  ? -17.58556 -17.78793 -1.42751  1.000 12.21902 ? 1556 KCX A HG3  1 
HETATM 1369 H  HD2  . KCX A 1 97  ? -16.16806 -17.05939 -3.01001  1.000 12.49695 ? 1556 KCX A HD2  1 
HETATM 1370 H  HD3  . KCX A 1 97  ? -15.87037 -15.96478 -2.20229  1.000 12.49695 ? 1556 KCX A HD3  1 
HETATM 1371 H  HE2  . KCX A 1 97  ? -17.21559 -15.27724 -3.77901  1.000 13.16334 ? 1556 KCX A HE2  1 
HETATM 1372 H  HE3  . KCX A 1 97  ? -17.90691 -15.16967 -2.57496  1.000 13.16334 ? 1556 KCX A HE3  1 
HETATM 1373 H  HZ   . KCX A 1 97  ? -18.62236 -17.38457 -3.35683  1.000 13.27389 ? 1556 KCX A HZ   1 
ATOM   1374 N  N    A LEU A 1 98  ? -15.01320 -15.11949 0.66281   0.345 9.65118  ? 1557 LEU A N    1 
ATOM   1375 N  N    B LEU A 1 98  ? -15.03953 -15.11675 0.63416   0.655 9.65118  ? 1557 LEU A N    1 
ATOM   1376 C  CA   A LEU A 1 98  ? -15.61157 -14.03132 1.43868   0.345 10.44343 ? 1557 LEU A CA   1 
ATOM   1377 C  CA   B LEU A 1 98  ? -15.67457 -14.03614 1.37616   0.655 10.44343 ? 1557 LEU A CA   1 
ATOM   1378 C  C    A LEU A 1 98  ? -16.77197 -13.51905 0.61255   0.345 10.49865 ? 1557 LEU A C    1 
ATOM   1379 C  C    B LEU A 1 98  ? -16.83827 -13.48566 0.55242   0.655 10.49865 ? 1557 LEU A C    1 
ATOM   1380 O  O    A LEU A 1 98  ? -16.57465 -13.16098 -0.54858  0.345 11.03555 ? 1557 LEU A O    1 
ATOM   1381 O  O    B LEU A 1 98  ? -16.65642 -13.08118 -0.59876  0.655 11.03555 ? 1557 LEU A O    1 
ATOM   1382 C  CB   A LEU A 1 98  ? -14.64548 -12.87817 1.68974   0.345 29.91312 ? 1557 LEU A CB   1 
ATOM   1383 C  CB   B LEU A 1 98  ? -14.71911 -12.87538 1.65161   0.655 29.91312 ? 1557 LEU A CB   1 
ATOM   1384 C  CG   A LEU A 1 98  ? -13.89413 -12.91553 3.02861   0.345 29.91317 ? 1557 LEU A CG   1 
ATOM   1385 C  CG   B LEU A 1 98  ? -13.28091 -13.11916 2.11325   0.655 29.91317 ? 1557 LEU A CG   1 
ATOM   1386 C  CD1  A LEU A 1 98  ? -13.04973 -14.18613 2.98645   0.345 29.91317 ? 1557 LEU A CD1  1 
ATOM   1387 C  CD1  B LEU A 1 98  ? -12.59748 -11.80279 2.58763   0.655 29.91317 ? 1557 LEU A CD1  1 
ATOM   1388 C  CD2  A LEU A 1 98  ? -13.04943 -11.70002 3.35101   0.345 29.91317 ? 1557 LEU A CD2  1 
ATOM   1389 C  CD2  B LEU A 1 98  ? -13.14129 -14.18554 3.16224   0.655 29.91317 ? 1557 LEU A CD2  1 
ATOM   1390 H  H    A LEU A 1 98  ? -14.53452 -14.84981 0.00119   0.345 11.58421 ? 1557 LEU A H    1 
ATOM   1391 H  H    B LEU A 1 98  ? -14.55863 -14.84917 -0.02670  0.655 11.58421 ? 1557 LEU A H    1 
ATOM   1392 H  HA   A LEU A 1 98  ? -15.87646 -14.35048 2.31553   0.345 12.53491 ? 1557 LEU A HA   1 
ATOM   1393 H  HA   B LEU A 1 98  ? -15.96938 -14.38809 2.23063   0.655 12.53491 ? 1557 LEU A HA   1 
ATOM   1394 H  HB2  A LEU A 1 98  ? -13.97890 -12.88215 0.98507   0.345 35.89854 ? 1557 LEU A HB2  1 
ATOM   1395 H  HB2  B LEU A 1 98  ? -14.64908 -12.36766 0.82807   0.655 35.89854 ? 1557 LEU A HB2  1 
ATOM   1396 H  HB3  A LEU A 1 98  ? -15.14932 -12.04965 1.66513   0.345 35.89854 ? 1557 LEU A HB3  1 
ATOM   1397 H  HB3  B LEU A 1 98  ? -15.12914 -12.33190 2.34256   0.655 35.89854 ? 1557 LEU A HB3  1 
ATOM   1398 H  HG   A LEU A 1 98  ? -14.53763 -12.90970 3.75439   0.345 35.89860 ? 1557 LEU A HG   1 
ATOM   1399 H  HG   B LEU A 1 98  ? -12.81292 -13.45129 1.33122   0.655 35.89860 ? 1557 LEU A HG   1 
ATOM   1400 H  HD11 A LEU A 1 98  ? -12.53569 -14.25105 3.80648   0.345 35.89860 ? 1557 LEU A HD11 1 
ATOM   1401 H  HD11 B LEU A 1 98  ? -11.69631 -12.00413 2.88471   0.655 35.89860 ? 1557 LEU A HD11 1 
ATOM   1402 H  HD12 A LEU A 1 98  ? -13.63745 -14.95326 2.90285   0.345 35.89860 ? 1557 LEU A HD12 1 
ATOM   1403 H  HD12 B LEU A 1 98  ? -12.56957 -11.17684 1.84715   0.655 35.89860 ? 1557 LEU A HD12 1 
ATOM   1404 H  HD13 A LEU A 1 98  ? -12.45186 -14.14282 2.22383   0.345 35.89860 ? 1557 LEU A HD13 1 
ATOM   1405 H  HD13 B LEU A 1 98  ? -13.11076 -11.42652 3.31966   0.655 35.89860 ? 1557 LEU A HD13 1 
ATOM   1406 H  HD21 A LEU A 1 98  ? -12.44710 -11.91821 4.07935   0.345 35.89860 ? 1557 LEU A HD21 1 
ATOM   1407 H  HD21 B LEU A 1 98  ? -12.19985 -14.31764 3.35493   0.655 35.89860 ? 1557 LEU A HD21 1 
ATOM   1408 H  HD22 A LEU A 1 98  ? -12.54015 -11.45154 2.56374   0.345 35.89860 ? 1557 LEU A HD22 1 
ATOM   1409 H  HD22 B LEU A 1 98  ? -13.60656 -13.90196 3.96474   0.655 35.89860 ? 1557 LEU A HD22 1 
ATOM   1410 H  HD23 A LEU A 1 98  ? -13.63279 -10.97015 3.61156   0.345 35.89860 ? 1557 LEU A HD23 1 
ATOM   1411 H  HD23 B LEU A 1 98  ? -13.52942 -15.00950 2.82856   0.655 35.89860 ? 1557 LEU A HD23 1 
ATOM   1412 N  N    A TYR A 1 99  ? -17.97274 -13.48033 1.17981   0.345 10.65919 ? 1558 TYR A N    1 
ATOM   1413 N  N    B TYR A 1 99  ? -18.02989 -13.45766 1.15260   0.655 10.65656 ? 1558 TYR A N    1 
ATOM   1414 C  CA   A TYR A 1 99  ? -19.10512 -12.85459 0.51275   0.345 11.58299 ? 1558 TYR A CA   1 
ATOM   1415 C  CA   B TYR A 1 99  ? -19.22741 -12.86504 0.55698   0.655 11.58036 ? 1558 TYR A CA   1 
ATOM   1416 C  C    A TYR A 1 99  ? -19.29852 -11.49931 1.17157   0.345 11.16452 ? 1558 TYR A C    1 
ATOM   1417 C  C    B TYR A 1 99  ? -19.32550 -11.48777 1.19155   0.655 11.16452 ? 1558 TYR A C    1 
ATOM   1418 O  O    A TYR A 1 99  ? -19.74260 -11.41752 2.32063   0.345 12.45151 ? 1558 TYR A O    1 
ATOM   1419 O  O    B TYR A 1 99  ? -19.72313 -11.37254 2.34977   0.655 12.45414 ? 1558 TYR A O    1 
ATOM   1420 C  CB   A TYR A 1 99  ? -20.38157 -13.67350 0.61783   0.345 12.39624 ? 1558 TYR A CB   1 
ATOM   1421 C  CB   B TYR A 1 99  ? -20.48441 -13.68546 0.87767   0.655 12.39887 ? 1558 TYR A CB   1 
ATOM   1422 C  CG   A TYR A 1 99  ? -21.35455 -13.31025 -0.48881  0.345 12.91736 ? 1558 TYR A CG   1 
ATOM   1423 C  CG   B TYR A 1 99  ? -20.58954 -14.94179 0.05929   0.655 12.92788 ? 1558 TYR A CG   1 
ATOM   1424 C  CD1  A TYR A 1 99  ? -22.12630 -12.16339 -0.40660  0.345 12.67786 ? 1558 TYR A CD1  1 
ATOM   1425 C  CD1  B TYR A 1 99  ? -21.19468 -14.92158 -1.18591  0.655 12.67522 ? 1558 TYR A CD1  1 
ATOM   1426 C  CD2  A TYR A 1 99  ? -21.47532 -14.10235 -1.62599  0.345 12.74365 ? 1558 TYR A CD2  1 
ATOM   1427 C  CD2  B TYR A 1 99  ? -20.08554 -16.13876 0.52422   0.655 12.74628 ? 1558 TYR A CD2  1 
ATOM   1428 C  CE1  A TYR A 1 99  ? -22.99314 -11.82180 -1.41719  0.345 12.44098 ? 1558 TYR A CE1  1 
ATOM   1429 C  CE1  B TYR A 1 99  ? -21.26964 -16.05193 -1.95585  0.655 12.44362 ? 1558 TYR A CE1  1 
ATOM   1430 C  CE2  A TYR A 1 99  ? -22.35929 -13.78414 -2.63272  0.345 12.31202 ? 1558 TYR A CE2  1 
ATOM   1431 C  CE2  B TYR A 1 99  ? -20.16836 -17.28796 -0.23363  0.655 12.31202 ? 1558 TYR A CE2  1 
ATOM   1432 C  CZ   A TYR A 1 99  ? -23.10439 -12.63567 -2.53451  0.345 11.65405 ? 1558 TYR A CZ   1 
ATOM   1433 C  CZ   B TYR A 1 99  ? -20.72941 -17.23575 -1.47687  0.655 11.65931 ? 1558 TYR A CZ   1 
ATOM   1434 O  OH   A TYR A 1 99  ? -23.97420 -12.31727 -3.55094  0.345 10.59340 ? 1558 TYR A OH   1 
ATOM   1435 O  OH   B TYR A 1 99  ? -20.78293 -18.38170 -2.22817  0.655 10.55129 ? 1558 TYR A OH   1 
ATOM   1436 H  H    B TYR A 1 99  ? -18.17384 -13.78787 1.93352   0.655 12.79067 ? 1558 TYR A H    1 
ATOM   1437 H  HA   A TYR A 1 99  ? -18.90395 -12.76280 -0.43171  0.345 13.90238 ? 1558 TYR A HA   1 
ATOM   1438 H  HA   B TYR A 1 99  ? -19.14335 -12.81813 -0.40823  0.655 13.89922 ? 1558 TYR A HA   1 
ATOM   1439 H  HB2  A TYR A 1 99  ? -20.16685 -14.61634 0.54136   0.345 14.87829 ? 1558 TYR A HB2  1 
ATOM   1440 H  HB2  B TYR A 1 99  ? -20.46479 -13.93870 1.81382   0.655 14.88145 ? 1558 TYR A HB2  1 
ATOM   1441 H  HB3  A TYR A 1 99  ? -20.80748 -13.49842 1.47156   0.345 14.87829 ? 1558 TYR A HB3  1 
ATOM   1442 H  HB3  B TYR A 1 99  ? -21.26854 -13.14385 0.69686   0.655 14.88145 ? 1558 TYR A HB3  1 
ATOM   1443 H  HD1  A TYR A 1 99  ? -22.05715 -11.61681 0.34264   0.345 15.21622 ? 1558 TYR A HD1  1 
ATOM   1444 H  HD1  B TYR A 1 99  ? -21.55660 -14.12657 -1.50511  0.655 15.21307 ? 1558 TYR A HD1  1 
ATOM   1445 H  HD2  A TYR A 1 99  ? -20.94741 -14.86358 -1.70812  0.345 15.29518 ? 1558 TYR A HD2  1 
ATOM   1446 H  HD2  B TYR A 1 99  ? -19.68346 -16.17128 1.36218   0.655 15.29834 ? 1558 TYR A HD2  1 
ATOM   1447 H  HE1  A TYR A 1 99  ? -23.50354 -11.04712 -1.35184  0.345 14.93198 ? 1558 TYR A HE1  1 
ATOM   1448 H  HE1  B TYR A 1 99  ? -21.67842 -16.02571 -2.79079  0.655 14.93514 ? 1558 TYR A HE1  1 
ATOM   1449 H  HE2  A TYR A 1 99  ? -22.45047 -14.34161 -3.37151  0.345 14.77722 ? 1558 TYR A HE2  1 
ATOM   1450 H  HE2  B TYR A 1 99  ? -19.84410 -18.09316 0.10014   0.655 14.77722 ? 1558 TYR A HE2  1 
ATOM   1451 H  HH   A TYR A 1 99  ? -24.37632 -11.60195 -3.37145  0.345 12.71487 ? 1558 TYR A HH   1 
ATOM   1452 H  HH   B TYR A 1 99  ? -21.20446 -18.23877 -2.94055  0.655 12.66434 ? 1558 TYR A HH   1 
ATOM   1453 N  N    . LEU A 1 100 ? -18.94419 -10.44027 0.45648   1.000 10.67236 ? 1559 LEU A N    1 
ATOM   1454 C  CA   . LEU A 1 100 ? -18.82487 -9.12535  1.07196   1.000 12.04620 ? 1559 LEU A CA   1 
ATOM   1455 C  C    . LEU A 1 100 ? -19.97514 -8.19852  0.75199   1.000 13.96749 ? 1559 LEU A C    1 
ATOM   1456 O  O    . LEU A 1 100 ? -20.02445 -7.09902  1.30729   1.000 16.08616 ? 1559 LEU A O    1 
ATOM   1457 C  CB   . LEU A 1 100 ? -17.50159 -8.47120  0.68108   1.000 11.58299 ? 1559 LEU A CB   1 
ATOM   1458 C  CG   . LEU A 1 100 ? -16.28201 -9.32585  1.06267   1.000 12.44888 ? 1559 LEU A CG   1 
ATOM   1459 C  CD1  . LEU A 1 100 ? -15.02039 -8.56046  0.70738   1.000 12.45151 ? 1559 LEU A CD1  1 
ATOM   1460 C  CD2  . LEU A 1 100 ? -16.30012 -9.65008  2.53788   1.000 13.79114 ? 1559 LEU A CD2  1 
ATOM   1461 H  H    . LEU A 1 100 ? -18.75398 -10.46831 -0.38175  1.000 12.80962 ? 1559 LEU A H    1 
ATOM   1462 H  HA   . LEU A 1 100 ? -18.81568 -9.24014  2.03510   1.000 14.45824 ? 1559 LEU A HA   1 
ATOM   1463 H  HB2  . LEU A 1 100 ? -17.48741 -8.33793  -0.27961  1.000 13.90239 ? 1559 LEU A HB2  1 
ATOM   1464 H  HB3  . LEU A 1 100 ? -17.42544 -7.61766  1.13558   1.000 13.90239 ? 1559 LEU A HB3  1 
ATOM   1465 H  HG   . LEU A 1 100 ? -16.29961 -10.16561 0.57749   1.000 14.94145 ? 1559 LEU A HG   1 
ATOM   1466 H  HD11 . LEU A 1 100 ? -14.24827 -9.10496  0.92704   1.000 14.94461 ? 1559 LEU A HD11 1 
ATOM   1467 H  HD12 . LEU A 1 100 ? -15.02715 -8.36398  -0.24249  1.000 14.94461 ? 1559 LEU A HD12 1 
ATOM   1468 H  HD13 . LEU A 1 100 ? -14.99825 -7.73469  1.21582   1.000 14.94461 ? 1559 LEU A HD13 1 
ATOM   1469 H  HD21 . LEU A 1 100 ? -15.39706 -9.85366  2.82759   1.000 16.55217 ? 1559 LEU A HD21 1 
ATOM   1470 H  HD22 . LEU A 1 100 ? -16.63901 -8.88317  3.02563   1.000 16.55217 ? 1559 LEU A HD22 1 
ATOM   1471 H  HD23 . LEU A 1 100 ? -16.87566 -10.41677 2.68567   1.000 16.55217 ? 1559 LEU A HD23 1 
ATOM   1472 N  N    . ASN A 1 101 ? -20.88607 -8.60401  -0.11597  1.000 14.82548 ? 1560 ASN A N    1 
ATOM   1473 C  CA   . ASN A 1 101 ? -22.11487 -7.85934  -0.38220  1.000 16.54938 ? 1560 ASN A CA   1 
ATOM   1474 C  C    . ASN A 1 101 ? -23.27271 -8.67057  0.23014   1.000 22.62115 ? 1560 ASN A C    1 
ATOM   1475 O  O    . ASN A 1 101 ? -23.10009 -9.20901  1.32501   1.000 23.00804 ? 1560 ASN A O    1 
ATOM   1476 C  CB   . ASN A 1 101 ? -22.20546 -7.53847  -1.87020  1.000 14.78074 ? 1560 ASN A CB   1 
ATOM   1477 C  CG   . ASN A 1 101 ? -21.03144 -6.70779  -2.36288  1.000 14.09382 ? 1560 ASN A CG   1 
ATOM   1478 O  OD1  . ASN A 1 101 ? -20.17834 -7.18709  -3.08611  1.000 13.74114 ? 1560 ASN A OD1  1 
ATOM   1479 N  ND2  . ASN A 1 101 ? -20.96126 -5.47256  -1.91060  1.000 15.30975 ? 1560 ASN A ND2  1 
ATOM   1480 H  H    . ASN A 1 101 ? -20.81921 -9.32585  -0.57864  1.000 17.79338 ? 1560 ASN A H    1 
ATOM   1481 H  HA   . ASN A 1 101 ? -22.15713 -6.98190  0.02916   1.000 19.86205 ? 1560 ASN A HA   1 
ATOM   1482 H  HB2  . ASN A 1 101 ? -22.21818 -8.36811  -2.37262  1.000 17.73969 ? 1560 ASN A HB2  1 
ATOM   1483 H  HB3  . ASN A 1 101 ? -23.01898 -7.03717  -2.03687  1.000 17.73969 ? 1560 ASN A HB3  1 
ATOM   1484 H  HD21 . ASN A 1 101 ? -20.31662 -4.95997  -2.15818  1.000 18.37450 ? 1560 ASN A HD21 1 
ATOM   1485 H  HD22 . ASN A 1 101 ? -21.56008 -5.17873  -1.36775  1.000 18.37450 ? 1560 ASN A HD22 1 
ATOM   1486 N  N    . GLU A 1 102 ? -24.41583 -8.81056  -0.44914  0.803 27.52437 ? 1561 GLU A N    1 
ATOM   1487 C  CA   . GLU A 1 102 ? -25.62301 -9.47602  0.08633   0.803 32.81711 ? 1561 GLU A CA   1 
ATOM   1488 C  C    . GLU A 1 102 ? -25.51792 -10.60351 1.12240   0.803 37.16761 ? 1561 GLU A C    1 
ATOM   1489 O  O    . GLU A 1 102 ? -25.43120 -10.31714 2.31938   0.803 38.57043 ? 1561 GLU A O    1 
ATOM   1490 C  CB   . GLU A 1 102 ? -26.46277 -9.97711  -1.10657  0.803 33.72511 ? 1561 GLU A CB   1 
ATOM   1491 H  H    . GLU A 1 102 ? -24.52814 -8.52061  -1.25096  0.803 33.03204 ? 1561 GLU A H    1 
ATOM   1492 H  HA   . GLU A 1 102 ? -26.03098 -8.77734  0.62140   0.803 39.38333 ? 1561 GLU A HA   1 
ATOM   1493 N  N    . THR A 1 103 ? -25.66479 -11.87196 0.70074   1.000 30.29314 ? 1562 THR A N    1 
ATOM   1494 C  CA   . THR A 1 103 ? -25.38390 -13.06408 1.50529   1.000 30.07205 ? 1562 THR A CA   1 
ATOM   1495 C  C    . THR A 1 103 ? -26.51953 -13.57963 2.38898   1.000 30.07468 ? 1562 THR A C    1 
ATOM   1496 O  O    . THR A 1 103 ? -27.43580 -12.83041 2.76110   1.000 30.07468 ? 1562 THR A O    1 
ATOM   1497 C  CB   . THR A 1 103 ? -24.13329 -12.84631 2.38802   1.000 30.06415 ? 1562 THR A CB   1 
ATOM   1498 H  H    . THR A 1 103 ? -25.94007 -12.07450 -0.08844  0.765 36.35457 ? 1562 THR A H    1 
ATOM   1499 H  HA   . THR A 1 103 ? -25.23789 -13.76122 0.84682   1.000 36.08925 ? 1562 THR A HA   1 
ATOM   1500 N  N    . PHE A 1 104 ? -26.45291 -14.86585 2.73406   0.732 30.07468 ? 1563 PHE A N    1 
ATOM   1501 C  CA   . PHE A 1 104 ? -27.27066 -15.46497 3.77617   0.732 30.06678 ? 1563 PHE A CA   1 
ATOM   1502 C  C    . PHE A 1 104 ? -26.68665 -15.20546 5.16500   0.732 30.07468 ? 1563 PHE A C    1 
ATOM   1503 O  O    . PHE A 1 104 ? -25.47928 -15.01993 5.34283   0.732 30.06941 ? 1563 PHE A O    1 
ATOM   1504 C  CB   . PHE A 1 104 ? -27.32956 -16.97884 3.57539   0.732 30.07468 ? 1563 PHE A CB   1 
ATOM   1505 H  H    . PHE A 1 104 ? -25.92071 -15.43055 2.36329   0.732 36.09241 ? 1563 PHE A H    1 
ATOM   1506 H  HA   . PHE A 1 104 ? -28.15904 -15.07811 3.73134   0.732 36.08294 ? 1563 PHE A HA   1 
ATOM   1507 N  N    . SER A 1 105 ? -27.56030 -15.26107 6.17389   0.588 30.07468 ? 1564 SER A N    1 
ATOM   1508 C  CA   . SER A 1 105 ? -27.15231 -14.90757 7.53155   0.588 30.07205 ? 1564 SER A CA   1 
ATOM   1509 C  C    . SER A 1 105 ? -25.82343 -15.53988 7.93738   0.588 30.07468 ? 1564 SER A C    1 
ATOM   1510 O  O    . SER A 1 105 ? -25.05017 -14.92791 8.68606   0.588 30.07468 ? 1564 SER A O    1 
ATOM   1511 C  CB   . SER A 1 105 ? -28.25080 -15.30739 8.52333   0.588 30.07468 ? 1564 SER A CB   1 
ATOM   1512 H  H    . SER A 1 105 ? -28.38381 -15.49726 6.09873   0.588 36.09241 ? 1564 SER A H    1 
ATOM   1513 H  HA   . SER A 1 105 ? -27.03316 -13.94564 7.56880   0.588 36.08925 ? 1564 SER A HA   1 
ATOM   1514 N  N    . GLU A 1 106 ? -25.52803 -16.75027 7.45038   0.620 30.07468 ? 1565 GLU A N    1 
ATOM   1515 C  CA   . GLU A 1 106 ? -24.34118 -17.46281 7.92079   0.593 30.07205 ? 1565 GLU A CA   1 
ATOM   1516 C  C    . GLU A 1 106 ? -23.04418 -17.00039 7.25006   0.916 30.07731 ? 1565 GLU A C    1 
ATOM   1517 O  O    . GLU A 1 106 ? -21.98309 -17.07686 7.87401   0.835 30.06678 ? 1565 GLU A O    1 
ATOM   1518 C  CB   . GLU A 1 106 ? -24.53492 -18.97840 7.78829   1.000 30.06678 ? 1565 GLU A CB   1 
ATOM   1519 H  H    . GLU A 1 106 ? -25.99026 -17.17037 6.85923   1.000 36.09241 ? 1565 GLU A H    1 
ATOM   1520 H  HA   . GLU A 1 106 ? -24.23426 -17.27180 8.86577   1.000 36.08925 ? 1565 GLU A HA   1 
ATOM   1521 N  N    . LEU A 1 107 ? -23.08378 -16.51965 6.00591   1.000 30.05889 ? 1566 LEU A N    1 
ATOM   1522 C  CA   . LEU A 1 107 ? -21.89110 -16.00241 5.33119   1.000 30.05889 ? 1566 LEU A CA   1 
ATOM   1523 C  C    . LEU A 1 107 ? -21.80667 -14.47457 5.38190   1.000 30.04571 ? 1566 LEU A C    1 
ATOM   1524 O  O    . LEU A 1 107 ? -20.83094 -13.88508 4.89936   1.000 30.05889 ? 1566 LEU A O    1 
ATOM   1525 C  CB   . LEU A 1 107 ? -21.87146 -16.51562 3.88853   1.000 30.05889 ? 1566 LEU A CB   1 
ATOM   1526 C  CG   . LEU A 1 107 ? -21.78043 -18.05090 3.81717   1.000 30.05889 ? 1566 LEU A CG   1 
ATOM   1527 C  CD1  . LEU A 1 107 ? -22.52080 -18.60722 2.61651   1.000 30.05889 ? 1566 LEU A CD1  1 
ATOM   1528 C  CD2  . LEU A 1 107 ? -20.33793 -18.48298 3.77549   1.000 30.05889 ? 1566 LEU A CD2  1 
ATOM   1529 H  H    . LEU A 1 107 ? -23.79714 -16.48212 5.52704   1.000 36.07346 ? 1566 LEU A H    1 
ATOM   1530 H  HA   . LEU A 1 107 ? -21.09014 -16.33571 5.76510   1.000 36.07346 ? 1566 LEU A HA   1 
ATOM   1531 H  HB2  . LEU A 1 107 ? -22.68734 -16.23925 3.44260   1.000 36.07346 ? 1566 LEU A HB2  1 
ATOM   1532 H  HB3  . LEU A 1 107 ? -21.10105 -16.14464 3.43054   1.000 36.07346 ? 1566 LEU A HB3  1 
ATOM   1533 H  HG   . LEU A 1 107 ? -22.20162 -18.41452 4.61170   1.000 36.07346 ? 1566 LEU A HG   1 
ATOM   1534 H  HD11 . LEU A 1 107 ? -22.43408 -19.57332 2.61186   1.000 36.07346 ? 1566 LEU A HD11 1 
ATOM   1535 H  HD12 . LEU A 1 107 ? -23.45647 -18.35940 2.67982   1.000 36.07346 ? 1566 LEU A HD12 1 
ATOM   1536 H  HD13 . LEU A 1 107 ? -22.13443 -18.23653 1.80768   1.000 36.07346 ? 1566 LEU A HD13 1 
ATOM   1537 H  HD21 . LEU A 1 107 ? -20.29952 -19.45089 3.72471   1.000 36.07346 ? 1566 LEU A HD21 1 
ATOM   1538 H  HD22 . LEU A 1 107 ? -19.91410 -18.09371 2.99463   1.000 36.07346 ? 1566 LEU A HD22 1 
ATOM   1539 H  HD23 . LEU A 1 107 ? -19.89294 -18.17608 4.58090   1.000 36.07346 ? 1566 LEU A HD23 1 
ATOM   1540 N  N    . ARG A 1 108 ? -22.76769 -13.83568 6.02059   1.000 22.22638 ? 1567 ARG A N    1 
ATOM   1541 C  CA   . ARG A 1 108 ? -22.79519 -12.38479 6.08298   1.000 23.16069 ? 1567 ARG A CA   1 
ATOM   1542 C  C    . ARG A 1 108 ? -21.74120 -11.90000 7.05989   1.000 20.13138 ? 1567 ARG A C    1 
ATOM   1543 O  O    . ARG A 1 108 ? -21.64004 -12.40093 8.18411   1.000 19.60500 ? 1567 ARG A O    1 
ATOM   1544 C  CB   . ARG A 1 108 ? -24.17867 -11.92540 6.54228   1.000 28.20602 ? 1567 ARG A CB   1 
ATOM   1545 H  H    . ARG A 1 108 ? -23.42037 -14.21863 6.42919   1.000 26.67446 ? 1567 ARG A H    1 
ATOM   1546 H  HA   . ARG A 1 108 ? -22.61102 -12.00603 5.20918   1.000 27.79563 ? 1567 ARG A HA   1 
ATOM   1547 N  N    . LEU A 1 109 ? -20.95650 -10.92170 6.63193   1.000 19.61027 ? 1568 LEU A N    1 
ATOM   1548 C  CA   . LEU A 1 109 ? -20.00704 -10.22752 7.48578   1.000 19.39182 ? 1568 LEU A CA   1 
ATOM   1549 C  C    . LEU A 1 109 ? -20.52074 -8.79819  7.63885   1.000 21.82632 ? 1568 LEU A C    1 
ATOM   1550 O  O    . LEU A 1 109 ? -20.93578 -8.17753  6.65762   1.000 24.03711 ? 1568 LEU A O    1 
ATOM   1551 C  CB   . LEU A 1 109 ? -18.60661 -10.26038 6.87560   1.000 17.78900 ? 1568 LEU A CB   1 
ATOM   1552 C  CG   . LEU A 1 109 ? -18.04957 -11.64903 6.54064   1.000 16.98627 ? 1568 LEU A CG   1 
ATOM   1553 C  CD1  . LEU A 1 109 ? -16.63005 -11.54361 5.94880   1.000 17.39421 ? 1568 LEU A CD1  1 
ATOM   1554 C  CD2  . LEU A 1 109 ? -18.02987 -12.61313 7.73312   1.000 17.42842 ? 1568 LEU A CD2  1 
ATOM   1555 H  H    . LEU A 1 109 ? -20.95663 -10.63276 5.82192   1.000 23.53512 ? 1568 LEU A H    1 
ATOM   1556 H  HA   . LEU A 1 109 ? -19.93855 -10.63852 8.36173   1.000 23.27298 ? 1568 LEU A HA   1 
ATOM   1557 H  HB2  . LEU A 1 109 ? -18.62492 -9.75184  6.04980   1.000 21.34959 ? 1568 LEU A HB2  1 
ATOM   1558 H  HB3  . LEU A 1 109 ? -17.99328 -9.84942  7.50476   1.000 21.34959 ? 1568 LEU A HB3  1 
ATOM   1559 H  HG   . LEU A 1 109 ? -18.65499 -12.02794 5.88430   1.000 20.38632 ? 1568 LEU A HG   1 
ATOM   1560 H  HD11 . LEU A 1 109 ? -16.30205 -12.43546 5.75408   1.000 20.87585 ? 1568 LEU A HD11 1 
ATOM   1561 H  HD12 . LEU A 1 109 ? -16.66592 -11.01907 5.13365   1.000 20.87585 ? 1568 LEU A HD12 1 
ATOM   1562 H  HD13 . LEU A 1 109 ? -16.04980 -11.11150 6.59493   1.000 20.87585 ? 1568 LEU A HD13 1 
ATOM   1563 H  HD21 . LEU A 1 109 ? -17.63528 -13.45382 7.45305   1.000 20.91691 ? 1568 LEU A HD21 1 
ATOM   1564 H  HD22 . LEU A 1 109 ? -17.50246 -12.22175 8.44696   1.000 20.91691 ? 1568 LEU A HD22 1 
ATOM   1565 H  HD23 . LEU A 1 109 ? -18.93967 -12.75941 8.03603   1.000 20.91691 ? 1568 LEU A HD23 1 
ATOM   1566 N  N    . ASP A 1 110 ? -20.55148 -8.30979  8.86134   1.000 22.98172 ? 1569 ASP A N    1 
ATOM   1567 C  CA   . ASP A 1 110 ? -21.13445 -7.00401  9.13079   1.000 24.31346 ? 1569 ASP A CA   1 
ATOM   1568 C  C    . ASP A 1 110 ? -20.10283 -5.91103  9.31743   1.000 22.13162 ? 1569 ASP A C    1 
ATOM   1569 O  O    . ASP A 1 110 ? -20.48159 -4.73727  9.42729   1.000 22.92645 ? 1569 ASP A O    1 
ATOM   1570 C  CB   . ASP A 1 110 ? -22.03929 -7.08991  10.36340  1.000 27.56385 ? 1569 ASP A CB   1 
ATOM   1571 C  CG   . ASP A 1 110 ? -21.32008 -7.68012  11.56368  1.000 31.64065 ? 1569 ASP A CG   1 
ATOM   1572 O  OD1  . ASP A 1 110 ? -20.36562 -7.03944  12.04505  1.000 33.34612 ? 1569 ASP A OD1  1 
ATOM   1573 O  OD2  . ASP A 1 110 ? -21.69864 -8.79434  12.01247  1.000 33.71722 ? 1569 ASP A OD2  1 
ATOM   1574 H  H    . ASP A 1 110 ? -20.24180 -8.71285  9.55505   1.000 27.58087 ? 1569 ASP A H    1 
ATOM   1575 H  HA   . ASP A 1 110 ? -21.68230 -6.74634  8.37292   1.000 29.17895 ? 1569 ASP A HA   1 
ATOM   1576 H  HB2  . ASP A 1 110 ? -22.34047 -6.19865  10.59973  1.000 33.07942 ? 1569 ASP A HB2  1 
ATOM   1577 H  HB3  . ASP A 1 110 ? -22.80133 -7.65455  10.15997  1.000 33.07942 ? 1569 ASP A HB3  1 
ATOM   1578 N  N    . SER A 1 111 ? -18.81387 -6.25113  9.29800   1.000 18.70753 ? 1570 SER A N    1 
ATOM   1579 C  CA   . SER A 1 111 ? -17.78309 -5.26040  9.55440   1.000 16.17038 ? 1570 SER A CA   1 
ATOM   1580 C  C    . SER A 1 111 ? -16.50537 -5.59268  8.80406   1.000 13.72009 ? 1570 SER A C    1 
ATOM   1581 O  O    . SER A 1 111 ? -16.10858 -6.75953  8.71712   1.000 13.34109 ? 1570 SER A O    1 
ATOM   1582 C  CB   . SER A 1 111 ? -17.45114 -5.23278  11.04337  1.000 16.28881 ? 1570 SER A CB   1 
ATOM   1583 O  OG   . SER A 1 111 ? -16.27610 -4.50097  11.26977  1.000 16.29671 ? 1570 SER A OG   1 
ATOM   1584 H  H    . SER A 1 111 ? -18.51890 -7.04330  9.13971   1.000 22.45183 ? 1570 SER A H    1 
ATOM   1585 H  HA   . SER A 1 111 ? -18.10144 -4.39951  9.24066   1.000 19.40725 ? 1570 SER A HA   1 
ATOM   1586 H  HB2  . SER A 1 111 ? -18.18282 -4.81494  11.52396  1.000 19.54937 ? 1570 SER A HB2  1 
ATOM   1587 H  HB3  . SER A 1 111 ? -17.32432 -6.14181  11.35718  1.000 19.54937 ? 1570 SER A HB3  1 
ATOM   1588 H  HG   . SER A 1 111 ? -16.10734 -4.47572  12.09226  1.000 19.55885 ? 1570 SER A HG   1 
ATOM   1589 N  N    . VAL A 1 112 ? -15.85161 -4.55392  8.27942   1.000 12.51731 ? 1571 VAL A N    1 
ATOM   1590 C  CA   A VAL A 1 112 ? -14.55226 -4.73989  7.63551   0.688 12.28044 ? 1571 VAL A CA   1 
ATOM   1591 C  CA   B VAL A 1 112 ? -14.55270 -4.74147  7.63473   0.312 12.20675 ? 1571 VAL A CA   1 
ATOM   1592 C  C    . VAL A 1 112 ? -13.54966 -5.36312  8.60181   1.000 11.43297 ? 1571 VAL A C    1 
ATOM   1593 O  O    . VAL A 1 112 ? -12.60132 -6.03836  8.17838   1.000 12.35413 ? 1571 VAL A O    1 
ATOM   1594 C  CB   A VAL A 1 112 ? -14.06351 -3.39385  7.05735   0.688 13.20950 ? 1571 VAL A CB   1 
ATOM   1595 C  CB   B VAL A 1 112 ? -14.01997 -3.41864  7.03931   0.312 13.00158 ? 1571 VAL A CB   1 
ATOM   1596 C  CG1  A VAL A 1 112 ? -12.63009 -3.50660  6.59178   0.688 12.95157 ? 1571 VAL A CG1  1 
ATOM   1597 C  CG1  B VAL A 1 112 ? -14.82593 -3.02864  5.80489   0.312 13.63850 ? 1571 VAL A CG1  1 
ATOM   1598 C  CG2  A VAL A 1 112 ? -14.98075 -2.94660  5.91851   0.688 14.47017 ? 1571 VAL A CG2  1 
ATOM   1599 C  CG2  B VAL A 1 112 ? -14.00416 -2.30785  8.08506   0.312 13.34899 ? 1571 VAL A CG2  1 
ATOM   1600 H  H    A VAL A 1 112 ? -16.13514 -3.74201  8.28323   0.688 15.02357 ? 1571 VAL A H    1 
ATOM   1601 H  H    B VAL A 1 112 ? -16.13458 -3.74182  8.28362   0.312 15.02357 ? 1571 VAL A H    1 
ATOM   1602 H  HA   A VAL A 1 112 ? -14.64826 -5.36017  6.89596   0.688 14.73933 ? 1571 VAL A HA   1 
ATOM   1603 H  HA   B VAL A 1 112 ? -14.68093 -5.35613  6.89537   0.312 14.65089 ? 1571 VAL A HA   1 
ATOM   1604 H  HB   A VAL A 1 112 ? -14.09427 -2.71666  7.75116   0.688 15.85420 ? 1571 VAL A HB   1 
ATOM   1605 H  HB   B VAL A 1 112 ? -13.10048 -3.54826  6.75890   0.312 15.60469 ? 1571 VAL A HB   1 
ATOM   1606 H  HG11 A VAL A 1 112 ? -12.42295 -2.75004  6.02115   0.688 15.54468 ? 1571 VAL A HG11 1 
ATOM   1607 H  HG11 B VAL A 1 112 ? -14.46441 -2.20648  5.43847   0.312 16.36899 ? 1571 VAL A HG11 1 
ATOM   1608 H  HG12 A VAL A 1 112 ? -12.04568 -3.50678  7.36596   0.688 15.54468 ? 1571 VAL A HG12 1 
ATOM   1609 H  HG12 B VAL A 1 112 ? -14.76185 -3.73972  5.14826   0.312 16.36899 ? 1571 VAL A HG12 1 
ATOM   1610 H  HG13 A VAL A 1 112 ? -12.52309 -4.33365  6.09636   0.688 15.54468 ? 1571 VAL A HG13 1 
ATOM   1611 H  HG13 B VAL A 1 112 ? -15.75226 -2.89741  6.06102   0.312 16.36899 ? 1571 VAL A HG13 1 
ATOM   1612 H  HG21 A VAL A 1 112 ? -14.62227 -2.13619  5.52401   0.688 17.36701 ? 1571 VAL A HG21 1 
ATOM   1613 H  HG21 B VAL A 1 112 ? -13.27483 -1.69932  7.88840   0.312 16.02158 ? 1571 VAL A HG21 1 
ATOM   1614 H  HG22 A VAL A 1 112 ? -15.02136 -3.64940  5.25118   0.688 17.36701 ? 1571 VAL A HG22 1 
ATOM   1615 H  HG22 B VAL A 1 112 ? -14.84914 -1.83253  8.05369   0.312 16.02158 ? 1571 VAL A HG22 1 
ATOM   1616 H  HG23 A VAL A 1 112 ? -15.86690 -2.77713  6.27475   0.688 17.36701 ? 1571 VAL A HG23 1 
ATOM   1617 H  HG23 B VAL A 1 112 ? -13.87870 -2.70192  8.96248   0.312 16.02158 ? 1571 VAL A HG23 1 
ATOM   1618 N  N    . VAL A 1 113 ? -13.72901 -5.15952  9.90886   1.000 11.73827 ? 1572 VAL A N    1 
ATOM   1619 C  CA   . VAL A 1 113 ? -12.82353 -5.78002  10.87806  1.000 12.88314 ? 1572 VAL A CA   1 
ATOM   1620 C  C    . VAL A 1 113 ? -12.88683 -7.29913  10.77544  1.000 12.43309 ? 1572 VAL A C    1 
ATOM   1621 O  O    . VAL A 1 113 ? -11.87553 -7.99141  10.92873  1.000 12.62522 ? 1572 VAL A O    1 
ATOM   1622 C  CB   . VAL A 1 113 ? -13.13094 -5.27466  12.29746  1.000 14.16488 ? 1572 VAL A CB   1 
ATOM   1623 C  CG1  . VAL A 1 113 ? -12.27308 -5.98614  13.35290  1.000 15.14394 ? 1572 VAL A CG1  1 
ATOM   1624 C  CG2  . VAL A 1 113 ? -12.91143 -3.73757  12.37598  1.000 14.52281 ? 1572 VAL A CG2  1 
ATOM   1625 H  H    . VAL A 1 113 ? -14.35261 -4.67770  10.25321  1.000 14.08872 ? 1572 VAL A H    1 
ATOM   1626 H  HA   . VAL A 1 113 ? -11.91463 -5.51548  10.66638  1.000 15.46257 ? 1572 VAL A HA   1 
ATOM   1627 H  HB   . VAL A 1 113 ? -14.05940 -5.47478  12.49447  1.000 17.00065 ? 1572 VAL A HB   1 
ATOM   1628 H  HG11 . VAL A 1 113 ? -12.35612 -5.51546  14.19698  1.000 18.17552 ? 1572 VAL A HG11 1 
ATOM   1629 H  HG12 . VAL A 1 113 ? -12.58592 -6.89905  13.45106  1.000 18.17552 ? 1572 VAL A HG12 1 
ATOM   1630 H  HG13 . VAL A 1 113 ? -11.34770 -5.98307  13.06210  1.000 18.17552 ? 1572 VAL A HG13 1 
ATOM   1631 H  HG21 . VAL A 1 113 ? -13.07330 -3.44150  13.28540  1.000 17.43017 ? 1572 VAL A HG21 1 
ATOM   1632 H  HG22 . VAL A 1 113 ? -11.99789 -3.53554  12.12000  1.000 17.43017 ? 1572 VAL A HG22 1 
ATOM   1633 H  HG23 . VAL A 1 113 ? -13.52934 -3.29898  11.77040  1.000 17.43017 ? 1572 VAL A HG23 1 
ATOM   1634 N  N    . GLN A 1 114 ? -14.07375 -7.83867  10.50130  1.000 12.12253 ? 1573 GLN A N    1 
ATOM   1635 C  CA   . GLN A 1 114 ? -14.19323 -9.27920  10.30416  1.000 12.03041 ? 1573 GLN A CA   1 
ATOM   1636 C  C    . GLN A 1 114 ? -13.44633 -9.72249  9.05258   1.000 10.91186 ? 1573 GLN A C    1 
ATOM   1637 O  O    . GLN A 1 114 ? -12.91532 -10.84945 9.00451   1.000 11.69616 ? 1573 GLN A O    1 
ATOM   1638 C  CB   . GLN A 1 114 ? -15.66647 -9.63592  10.15918  1.000 13.14370 ? 1573 GLN A CB   1 
ATOM   1639 C  CG   . GLN A 1 114 ? -16.42195 -9.64075  11.45379  1.000 15.91246 ? 1573 GLN A CG   1 
ATOM   1640 C  CD   . GLN A 1 114 ? -17.95213 -9.54285  11.27145  1.000 19.28128 ? 1573 GLN A CD   1 
ATOM   1641 O  OE1  . GLN A 1 114 ? -18.45662 -9.14043  10.21205  1.000 20.19454 ? 1573 GLN A OE1  1 
ATOM   1642 N  NE2  . GLN A 1 114 ? -18.68139 -9.99816  12.27382  1.000 21.87369 ? 1573 GLN A NE2  1 
ATOM   1643 H  H    . GLN A 1 114 ? -14.81028 -7.40116  10.42564  1.000 14.54983 ? 1573 GLN A H    1 
ATOM   1644 H  HA   . GLN A 1 114 ? -13.81835 -9.73946  11.07131  1.000 14.43929 ? 1573 GLN A HA   1 
ATOM   1645 H  HB2  . GLN A 1 114 ? -16.08748 -8.98686  9.57406   1.000 15.77524 ? 1573 GLN A HB2  1 
ATOM   1646 H  HB3  . GLN A 1 114 ? -15.73508 -10.52350 9.77396   1.000 15.77524 ? 1573 GLN A HB3  1 
ATOM   1647 H  HG2  . GLN A 1 114 ? -16.23110 -10.46676 11.92516  1.000 19.09774 ? 1573 GLN A HG2  1 
ATOM   1648 H  HG3  . GLN A 1 114 ? -16.13693 -8.88156  11.98604  1.000 19.09774 ? 1573 GLN A HG3  1 
ATOM   1649 H  HE21 . GLN A 1 114 ? -18.29797 -10.32321 12.97162  1.000 26.25123 ? 1573 GLN A HE21 1 
ATOM   1650 H  HE22 . GLN A 1 114 ? -19.53974 -9.96963  12.22880  1.000 26.25123 ? 1573 GLN A HE22 1 
ATOM   1651 N  N    . TRP A 1 115 ? -13.44423 -8.88935  8.01069   1.000 10.45127 ? 1574 TRP A N    1 
ATOM   1652 C  CA   . TRP A 1 115 ? -12.64563 -9.22217  6.84678   1.000 10.16966 ? 1574 TRP A CA   1 
ATOM   1653 C  C    . TRP A 1 115 ? -11.16810 -9.27254  7.22658   1.000 10.96712 ? 1574 TRP A C    1 
ATOM   1654 O  O    . TRP A 1 115 ? -10.44444 -10.19211 6.82780   1.000 11.31190 ? 1574 TRP A O    1 
ATOM   1655 C  CB   . TRP A 1 115 ? -12.79645 -8.22154  5.70712   1.000 10.60392 ? 1574 TRP A CB   1 
ATOM   1656 C  CG   . TRP A 1 115 ? -14.15540 -7.71791  5.32027   1.000 10.74868 ? 1574 TRP A CG   1 
ATOM   1657 C  CD1  . TRP A 1 115 ? -15.37000 -8.00361  5.87333   1.000 11.60667 ? 1574 TRP A CD1  1 
ATOM   1658 C  CD2  . TRP A 1 115 ? -14.39371 -6.74632  4.29909   1.000 10.62761 ? 1574 TRP A CD2  1 
ATOM   1659 N  NE1  . TRP A 1 115 ? -16.35356 -7.28749  5.22683   1.000 11.48561 ? 1574 TRP A NE1  1 
ATOM   1660 C  CE2  . TRP A 1 115 ? -15.77704 -6.50021  4.26091   1.000 10.73289 ? 1574 TRP A CE2  1 
ATOM   1661 C  CE3  . TRP A 1 115 ? -13.56298 -6.06595  3.39547   1.000 10.51181 ? 1574 TRP A CE3  1 
ATOM   1662 C  CZ2  . TRP A 1 115 ? -16.34042 -5.59121  3.36705   1.000 10.69867 ? 1574 TRP A CZ2  1 
ATOM   1663 C  CZ3  . TRP A 1 115 ? -14.10892 -5.17231  2.52987   1.000 10.88554 ? 1574 TRP A CZ3  1 
ATOM   1664 C  CH2  . TRP A 1 115 ? -15.48898 -4.94085  2.50333   1.000 11.09082 ? 1574 TRP A CH2  1 
ATOM   1665 H  H    . TRP A 1 115 ? -13.88343 -8.15169  7.95998   1.000 12.54433 ? 1574 TRP A H    1 
ATOM   1666 H  HA   . TRP A 1 115 ? -12.96974 -10.07930 6.52869   1.000 12.20639 ? 1574 TRP A HA   1 
ATOM   1667 H  HB2  . TRP A 1 115 ? -12.27734 -7.43706  5.94383   1.000 12.72750 ? 1574 TRP A HB2  1 
ATOM   1668 H  HB3  . TRP A 1 115 ? -12.42762 -8.63569  4.91130   1.000 12.72750 ? 1574 TRP A HB3  1 
ATOM   1669 H  HD1  . TRP A 1 115 ? -15.51210 -8.59217  6.57924   1.000 13.93080 ? 1574 TRP A HD1  1 
ATOM   1670 H  HE1  . TRP A 1 115 ? -17.19487 -7.32727  5.40066   1.000 13.78552 ? 1574 TRP A HE1  1 
ATOM   1671 H  HE3  . TRP A 1 115 ? -12.64678 -6.22540  3.38923   1.000 12.61697 ? 1574 TRP A HE3  1 
ATOM   1672 H  HZ2  . TRP A 1 115 ? -17.25633 -5.43040  3.35478   1.000 12.84120 ? 1574 TRP A HZ2  1 
ATOM   1673 H  HZ3  . TRP A 1 115 ? -13.55606 -4.70639  1.94492   1.000 13.06544 ? 1574 TRP A HZ3  1 
ATOM   1674 H  HH2  . TRP A 1 115 ? -15.83767 -4.33532  1.88961   1.000 13.31178 ? 1574 TRP A HH2  1 
ATOM   1675 N  N    . MET A 1 116 ? -10.70512 -8.26775  7.97399   1.000 11.30927 ? 1575 MET A N    1 
ATOM   1676 C  CA   A MET A 1 116 ? -9.30657  -8.25188  8.39020   0.573 12.95947 ? 1575 MET A CA   1 
ATOM   1677 C  CA   B MET A 1 116 ? -9.31004  -8.24168  8.40617   0.427 11.59615 ? 1575 MET A CA   1 
ATOM   1678 C  C    . MET A 1 116 ? -8.96586  -9.50113  9.18528   1.000 12.05410 ? 1575 MET A C    1 
ATOM   1679 O  O    . MET A 1 116 ? -7.90263  -10.09548 8.98949   1.000 12.73839 ? 1575 MET A O    1 
ATOM   1680 C  CB   A MET A 1 116 ? -9.00844  -7.01396  9.22761   0.573 15.12025 ? 1575 MET A CB   1 
ATOM   1681 C  CB   B MET A 1 116 ? -9.05517  -7.02825  9.29894   0.427 11.27769 ? 1575 MET A CB   1 
ATOM   1682 C  CG   A MET A 1 116 ? -8.93889  -5.73897  8.42175   0.573 17.53633 ? 1575 MET A CG   1 
ATOM   1683 C  CG   B MET A 1 116 ? -9.13955  -5.70151  8.58058   0.427 11.87250 ? 1575 MET A CG   1 
ATOM   1684 S  SD   A MET A 1 116 ? -8.27926  -4.37178  9.38467   0.573 19.52078 ? 1575 MET A SD   1 
ATOM   1685 S  SD   B MET A 1 116 ? -7.60331  -5.29050  7.70915   0.427 13.77798 ? 1575 MET A SD   1 
ATOM   1686 C  CE   A MET A 1 116 ? -9.83379  -3.90771  10.09794  0.573 19.72607 ? 1575 MET A CE   1 
ATOM   1687 C  CE   B MET A 1 116 ? -6.48024  -5.03539  9.07736   0.427 11.75406 ? 1575 MET A CE   1 
ATOM   1688 H  H    A MET A 1 116 ? -11.17127 -7.59846  8.24669   0.573 13.57392 ? 1575 MET A H    1 
ATOM   1689 H  H    B MET A 1 116 ? -11.17324 -7.59743  8.24071   0.427 13.57392 ? 1575 MET A H    1 
ATOM   1690 H  HA   A MET A 1 116 ? -8.75614  -8.21040  7.59257   0.573 15.55416 ? 1575 MET A HA   1 
ATOM   1691 H  HA   B MET A 1 116 ? -8.75117  -8.17047  7.61656   0.427 13.91817 ? 1575 MET A HA   1 
ATOM   1692 H  HB2  A MET A 1 116 ? -9.70975  -6.90853  9.88938   0.573 18.14710 ? 1575 MET A HB2  1 
ATOM   1693 H  HB2  B MET A 1 116 ? -9.71643  -7.02112  10.00857  0.427 13.53602 ? 1575 MET A HB2  1 
ATOM   1694 H  HB3  A MET A 1 116 ? -8.15232  -7.13362  9.66766   0.573 18.14710 ? 1575 MET A HB3  1 
ATOM   1695 H  HB3  B MET A 1 116 ? -8.16458  -7.10245  9.67608   0.427 13.53602 ? 1575 MET A HB3  1 
ATOM   1696 H  HG2  A MET A 1 116 ? -8.36091  -5.87695  7.65507   0.573 21.04640 ? 1575 MET A HG2  1 
ATOM   1697 H  HG2  B MET A 1 116 ? -9.85604  -5.73873  7.92778   0.427 14.24979 ? 1575 MET A HG2  1 
ATOM   1698 H  HG3  A MET A 1 116 ? -9.83099  -5.49923  8.12582   0.573 21.04640 ? 1575 MET A HG3  1 
ATOM   1699 H  HG3  B MET A 1 116 ? -9.31624  -5.00067  9.22750   0.427 14.24979 ? 1575 MET A HG3  1 
ATOM   1700 H  HE1  A MET A 1 116 ? -9.78233  -2.98572  10.39488  0.573 23.67408 ? 1575 MET A HE1  1 
ATOM   1701 H  HE1  B MET A 1 116 ? -5.66106  -4.63738  8.74352   0.427 14.10767 ? 1575 MET A HE1  1 
ATOM   1702 H  HE2  A MET A 1 116 ? -10.52907 -4.00116  9.42805   0.573 23.67408 ? 1575 MET A HE2  1 
ATOM   1703 H  HE2  B MET A 1 116 ? -6.89729  -4.44252  9.72193   0.427 14.10767 ? 1575 MET A HE2  1 
ATOM   1704 H  HE3  A MET A 1 116 ? -10.02102 -4.48818  10.85220  0.573 23.67408 ? 1575 MET A HE3  1 
ATOM   1705 H  HE3  B MET A 1 116 ? -6.28741  -5.89111  9.49142   0.427 14.10767 ? 1575 MET A HE3  1 
ATOM   1706 N  N    . GLU A 1 117 ? -9.85246  -9.89992  10.09532  1.000 11.21189 ? 1576 GLU A N    1 
ATOM   1707 C  CA   . GLU A 1 117 ? -9.59435  -11.08312 10.91568  1.000 11.73564 ? 1576 GLU A CA   1 
ATOM   1708 C  C    . GLU A 1 117 ? -9.42392  -12.32420 10.05776  1.000 11.27242 ? 1576 GLU A C    1 
ATOM   1709 O  O    . GLU A 1 117 ? -8.52928  -13.12886 10.30891  1.000 12.20675 ? 1576 GLU A O    1 
ATOM   1710 C  CB   . GLU A 1 117 ? -10.72580 -11.28446 11.92405  1.000 13.18844 ? 1576 GLU A CB   1 
ATOM   1711 C  CG   . GLU A 1 117 ? -10.72867 -10.27173 13.04508  1.000 15.27027 ? 1576 GLU A CG   1 
ATOM   1712 C  CD   . GLU A 1 117 ? -11.99520 -10.28951 13.88305  1.000 17.27578 ? 1576 GLU A CD   1 
ATOM   1713 O  OE1  . GLU A 1 117 ? -12.98789 -10.95388 13.49928  1.000 17.46264 ? 1576 GLU A OE1  1 
ATOM   1714 O  OE2  . GLU A 1 117 ? -11.98955 -9.62299  14.94183  1.000 18.89702 ? 1576 GLU A OE2  1 
ATOM   1715 H  H    . GLU A 1 117 ? -10.60157 -9.50956  10.25673  1.000 13.45707 ? 1576 GLU A H    1 
ATOM   1716 H  HA   . GLU A 1 117 ? -8.77163  -10.94210 11.40980  1.000 14.08556 ? 1576 GLU A HA   1 
ATOM   1717 H  HB2  . GLU A 1 117 ? -11.57417 -11.21404 11.45906  1.000 15.82893 ? 1576 GLU A HB2  1 
ATOM   1718 H  HB3  . GLU A 1 117 ? -10.63700 -12.16519 12.32071  1.000 15.82893 ? 1576 GLU A HB3  1 
ATOM   1719 H  HG2  . GLU A 1 117 ? -9.98129  -10.45696 13.63502  1.000 18.32712 ? 1576 GLU A HG2  1 
ATOM   1720 H  HG3  . GLU A 1 117 ? -10.63865 -9.38419  12.66421  1.000 18.32712 ? 1576 GLU A HG3  1 
ATOM   1721 N  N    . HIS A 1 118 ? -10.25409 -12.48179 9.03175   1.000 10.48549 ? 1577 HIS A N    1 
ATOM   1722 C  CA   . HIS A 1 118 ? -10.06248 -13.58495 8.09458   1.000 10.78816 ? 1577 HIS A CA   1 
ATOM   1723 C  C    . HIS A 1 118 ? -8.72440  -13.49777 7.35514   1.000 11.33296 ? 1577 HIS A C    1 
ATOM   1724 O  O    . HIS A 1 118 ? -7.99933  -14.49614 7.26494   1.000 12.10937 ? 1577 HIS A O    1 
ATOM   1725 C  CB   . HIS A 1 118 ? -11.24486 -13.68916 7.14733   1.000 11.75143 ? 1577 HIS A CB   1 
ATOM   1726 C  CG   . HIS A 1 118 ? -12.37310 -14.44278 7.75182   1.000 12.58311 ? 1577 HIS A CG   1 
ATOM   1727 N  ND1  . HIS A 1 118 ? -12.26683 -15.78051 8.05112   1.000 12.74892 ? 1577 HIS A ND1  1 
ATOM   1728 C  CD2  . HIS A 1 118 ? -13.58883 -14.04379 8.18626   1.000 13.02000 ? 1577 HIS A CD2  1 
ATOM   1729 C  CE1  . HIS A 1 118 ? -13.39709 -16.18901 8.60348   1.000 12.98579 ? 1577 HIS A CE1  1 
ATOM   1730 N  NE2  . HIS A 1 118 ? -14.21180 -15.15102 8.70531   1.000 12.79366 ? 1577 HIS A NE2  1 
ATOM   1731 H  H    . HIS A 1 118 ? -10.92534 -11.97326 8.85735   1.000 12.58538 ? 1577 HIS A H    1 
ATOM   1732 H  HA   . HIS A 1 118 ? -10.03351 -14.41162 8.60121   1.000 12.94859 ? 1577 HIS A HA   1 
ATOM   1733 H  HB2  . HIS A 1 118 ? -11.55763 -12.79756 6.92793   1.000 14.10451 ? 1577 HIS A HB2  1 
ATOM   1734 H  HB3  . HIS A 1 118 ? -10.96792 -14.15141 6.34077   1.000 14.10451 ? 1577 HIS A HB3  1 
ATOM   1735 H  HD2  . HIS A 1 118 ? -13.93716 -13.18263 8.14194   1.000 15.62680 ? 1577 HIS A HD2  1 
ATOM   1736 H  HE1  . HIS A 1 118 ? -13.58707 -17.05818 8.87434   1.000 15.58574 ? 1577 HIS A HE1  1 
ATOM   1737 H  HE2  . HIS A 1 118 ? -15.00297 -15.16766 9.04201   1.000 15.35519 ? 1577 HIS A HE2  1 
ATOM   1738 N  N    . PHE A 1 119 ? -8.37064  -12.32795 6.83086   1.000 10.74341 ? 1578 PHE A N    1 
ATOM   1739 C  CA   . PHE A 1 119 ? -7.10088  -12.18771 6.13260   1.000 10.83290 ? 1578 PHE A CA   1 
ATOM   1740 C  C    . PHE A 1 119 ? -5.90513  -12.43515 7.05480   1.000 11.49087 ? 1578 PHE A C    1 
ATOM   1741 O  O    . PHE A 1 119 ? -4.85943  -12.90469 6.59009   1.000 12.22780 ? 1578 PHE A O    1 
ATOM   1742 C  CB   . PHE A 1 119 ? -6.99562  -10.78347 5.53340   1.000 11.58562 ? 1578 PHE A CB   1 
ATOM   1743 C  CG   . PHE A 1 119 ? -7.54340  -10.67206 4.12426   1.000 11.33033 ? 1578 PHE A CG   1 
ATOM   1744 C  CD1  . PHE A 1 119 ? -8.91550  -10.63682 3.88817   1.000 11.21715 ? 1578 PHE A CD1  1 
ATOM   1745 C  CD2  . PHE A 1 119 ? -6.69019  -10.65104 3.02998   1.000 10.90133 ? 1578 PHE A CD2  1 
ATOM   1746 C  CE1  . PHE A 1 119 ? -9.40620  -10.53642 2.59575   1.000 11.69353 ? 1578 PHE A CE1  1 
ATOM   1747 C  CE2  . PHE A 1 119 ? -7.16558  -10.56382 1.73392   1.000 11.29874 ? 1578 PHE A CE2  1 
ATOM   1748 C  CZ   . PHE A 1 119 ? -8.53495  -10.52850 1.50732   1.000 11.93566 ? 1578 PHE A CZ   1 
ATOM   1749 H  H    . PHE A 1 119 ? -8.84214  -11.60956 6.86547   1.000 12.89489 ? 1578 PHE A H    1 
ATOM   1750 H  HA   . PHE A 1 119 ? -7.07224  -12.84305 5.41803   1.000 13.00228 ? 1578 PHE A HA   1 
ATOM   1751 H  HB2  . PHE A 1 119 ? -7.49440  -10.16822 6.09338   1.000 13.90554 ? 1578 PHE A HB2  1 
ATOM   1752 H  HB3  . PHE A 1 119 ? -6.06090  -10.52551 5.50788   1.000 13.90554 ? 1578 PHE A HB3  1 
ATOM   1753 H  HD1  . PHE A 1 119 ? -9.50766  -10.68103 4.60392   1.000 13.46338 ? 1578 PHE A HD1  1 
ATOM   1754 H  HD2  . PHE A 1 119 ? -5.77227  -10.69691 3.17214   1.000 13.08439 ? 1578 PHE A HD2  1 
ATOM   1755 H  HE1  . PHE A 1 119 ? -10.32314 -10.47390 2.45361   1.000 14.03503 ? 1578 PHE A HE1  1 
ATOM   1756 H  HE2  . PHE A 1 119 ? -6.57183  -10.52907 1.01897   1.000 13.56129 ? 1578 PHE A HE2  1 
ATOM   1757 H  HZ   . PHE A 1 119 ? -8.86730  -10.49988 0.63921   1.000 14.32559 ? 1578 PHE A HZ   1 
ATOM   1758 N  N    . GLU A 1 120 ? -6.04962  -12.13967 8.35089   1.000 12.13305 ? 1579 GLU A N    1 
ATOM   1759 C  CA   . GLU A 1 120 ? -4.98069  -12.32912 9.32534   1.000 13.05948 ? 1579 GLU A CA   1 
ATOM   1760 C  C    . GLU A 1 120 ? -4.83930  -13.78202 9.76413   1.000 14.05960 ? 1579 GLU A C    1 
ATOM   1761 O  O    . GLU A 1 120 ? -3.72655  -14.20090 10.10679  1.000 15.94140 ? 1579 GLU A O    1 
ATOM   1762 C  CB   . GLU A 1 120 ? -5.25508  -11.47489 10.56215  1.000 14.47807 ? 1579 GLU A CB   1 
ATOM   1763 C  CG   . GLU A 1 120 ? -5.02205  -10.03414 10.31981  1.000 16.29934 ? 1579 GLU A CG   1 
ATOM   1764 C  CD   . GLU A 1 120 ? -5.69405  -9.12887  11.31838  1.000 18.46539 ? 1579 GLU A CD   1 
ATOM   1765 O  OE1  . GLU A 1 120 ? -6.48359  -9.59720  12.17476  1.000 18.72595 ? 1579 GLU A OE1  1 
ATOM   1766 O  OE2  . GLU A 1 120 ? -5.41209  -7.91710  11.22857  1.000 20.42615 ? 1579 GLU A OE2  1 
ATOM   1767 H  H    . GLU A 1 120 ? -6.77125  -11.82244 8.69471   1.000 14.56246 ? 1579 GLU A H    1 
ATOM   1768 H  HA   . GLU A 1 120 ? -4.14722  -12.04915 8.91566   1.000 15.67418 ? 1579 GLU A HA   1 
ATOM   1769 H  HB2  . GLU A 1 120 ? -6.18109  -11.58989 10.82707  1.000 17.37648 ? 1579 GLU A HB2  1 
ATOM   1770 H  HB3  . GLU A 1 120 ? -4.66709  -11.75867 11.27953  1.000 17.37648 ? 1579 GLU A HB3  1 
ATOM   1771 H  HG2  . GLU A 1 120 ? -4.06837  -9.86176  10.36083  1.000 19.56201 ? 1579 GLU A HG2  1 
ATOM   1772 H  HG3  . GLU A 1 120 ? -5.36268  -9.80723  9.44039   1.000 19.56201 ? 1579 GLU A HG3  1 
ATOM   1773 N  N    . THR A 1 121 ? -5.92955  -14.55248 9.77510   1.000 13.37004 ? 1580 THR A N    1 
ATOM   1774 C  CA   . THR A 1 121 ? -5.92609  -15.90474 10.33130  1.000 13.39373 ? 1580 THR A CA   1 
ATOM   1775 C  C    . THR A 1 121 ? -5.88169  -17.01273 9.28454   1.000 12.22517 ? 1580 THR A C    1 
ATOM   1776 O  O    . THR A 1 121 ? -5.29155  -18.06464 9.54749   1.000 13.38847 ? 1580 THR A O    1 
ATOM   1777 C  CB   . THR A 1 121 ? -7.17011  -16.13836 11.20512  1.000 13.54638 ? 1580 THR A CB   1 
ATOM   1778 O  OG1  . THR A 1 121 ? -8.35520  -15.86547 10.44148  1.000 13.23319 ? 1580 THR A OG1  1 
ATOM   1779 C  CG2  . THR A 1 121 ? -7.14641  -15.29651 12.46790  1.000 15.15183 ? 1580 THR A CG2  1 
ATOM   1780 H  H    . THR A 1 121 ? -6.69292  -14.31019 9.46179   1.000 16.04685 ? 1580 THR A H    1 
ATOM   1781 H  HA   . THR A 1 121 ? -5.13493  -15.98253 10.88710  1.000 16.07527 ? 1580 THR A HA   1 
ATOM   1782 H  HB   . THR A 1 121 ? -7.18149  -17.06508 11.49142  1.000 16.25846 ? 1580 THR A HB   1 
ATOM   1783 H  HG1  . THR A 1 121 ? -9.03748  -15.99187 10.91489  1.000 15.88262 ? 1580 THR A HG1  1 
ATOM   1784 H  HG21 . THR A 1 121 ? -7.93924  -15.47194 12.99851  1.000 18.18500 ? 1580 THR A HG21 1 
ATOM   1785 H  HG22 . THR A 1 121 ? -6.36096  -15.51118 12.99505  1.000 18.18500 ? 1580 THR A HG22 1 
ATOM   1786 H  HG23 . THR A 1 121 ? -7.12349  -14.35439 12.23816  1.000 18.18500 ? 1580 THR A HG23 1 
ATOM   1787 N  N    . TRP A 1 122 ? -6.50386  -16.83033 8.13185   1.000 11.85144 ? 1581 TRP A N    1 
ATOM   1788 C  CA   . TRP A 1 122 ? -6.42332  -17.82771 7.06963   1.000 11.71195 ? 1581 TRP A CA   1 
ATOM   1789 C  C    . TRP A 1 122 ? -4.95941  -17.98928 6.66783   1.000 12.23833 ? 1581 TRP A C    1 
ATOM   1790 O  O    . TRP A 1 122 ? -4.21747  -16.99632 6.63230   1.000 12.61732 ? 1581 TRP A O    1 
ATOM   1791 C  CB   . TRP A 1 122 ? -7.26643  -17.34737 5.88469   1.000 11.35138 ? 1581 TRP A CB   1 
ATOM   1792 C  CG   . TRP A 1 122 ? -7.36033  -18.26041 4.71463   1.000 11.17504 ? 1581 TRP A CG   1 
ATOM   1793 C  CD1  . TRP A 1 122 ? -6.77931  -18.07700 3.50528   1.000 11.27505 ? 1581 TRP A CD1  1 
ATOM   1794 C  CD2  . TRP A 1 122 ? -8.07579  -19.50597 4.63174   1.000 10.45391 ? 1581 TRP A CD2  1 
ATOM   1795 N  NE1  . TRP A 1 122 ? -7.09855  -19.10686 2.65230   1.000 10.57497 ? 1581 TRP A NE1  1 
ATOM   1796 C  CE2  . TRP A 1 122 ? -7.88422  -20.00356 3.32836   1.000 10.10650 ? 1581 TRP A CE2  1 
ATOM   1797 C  CE3  . TRP A 1 122 ? -8.90898  -20.21438 5.51684   1.000 11.04082 ? 1581 TRP A CE3  1 
ATOM   1798 C  CZ2  . TRP A 1 122 ? -8.47420  -21.18632 2.89438   1.000 10.79868 ? 1581 TRP A CZ2  1 
ATOM   1799 C  CZ3  . TRP A 1 122 ? -9.47534  -21.39761 5.08458   1.000 11.43034 ? 1581 TRP A CZ3  1 
ATOM   1800 C  CH2  . TRP A 1 122 ? -9.26065  -21.86260 3.78851   1.000 11.23294 ? 1581 TRP A CH2  1 
ATOM   1801 H  H    . TRP A 1 122 ? -6.97920  -16.14113 7.93525   1.000 14.22453 ? 1581 TRP A H    1 
ATOM   1802 H  HA   . TRP A 1 122 ? -6.75765  -18.69221 7.35558   1.000 14.05714 ? 1581 TRP A HA   1 
ATOM   1803 H  HB2  . TRP A 1 122 ? -8.17133  -17.19884 6.20091   1.000 13.62446 ? 1581 TRP A HB2  1 
ATOM   1804 H  HB3  . TRP A 1 122 ? -6.88622  -16.51465 5.56388   1.000 13.62446 ? 1581 TRP A HB3  1 
ATOM   1805 H  HD1  . TRP A 1 122 ? -6.23868  -17.35385 3.28239   1.000 13.53286 ? 1581 TRP A HD1  1 
ATOM   1806 H  HE1  . TRP A 1 122 ? -6.84758  -19.17665 1.83271   1.000 12.69276 ? 1581 TRP A HE1  1 
ATOM   1807 H  HE3  . TRP A 1 122 ? -9.07466  -19.89314 6.37373   1.000 13.25178 ? 1581 TRP A HE3  1 
ATOM   1808 H  HZ2  . TRP A 1 122 ? -8.33981  -21.50514 2.03113   1.000 12.96122 ? 1581 TRP A HZ2  1 
ATOM   1809 H  HZ3  . TRP A 1 122 ? -10.00732 -21.89084 5.66649   1.000 13.71920 ? 1581 TRP A HZ3  1 
ATOM   1810 H  HH2  . TRP A 1 122 ? -9.66415  -22.65715 3.52245   1.000 13.48233 ? 1581 TRP A HH2  1 
ATOM   1811 N  N    . PRO A 1 123 ? -4.48445  -19.21202 6.41181   1.000 11.91461 ? 1582 PRO A N    1 
ATOM   1812 C  CA   . PRO A 1 123 ? -3.04964  -19.36442 6.09123   1.000 12.62522 ? 1582 PRO A CA   1 
ATOM   1813 C  C    . PRO A 1 123 ? -2.68389  -18.51081 4.88031   1.000 13.20160 ? 1582 PRO A C    1 
ATOM   1814 O  O    . PRO A 1 123 ? -3.39351  -18.46099 3.87572   1.000 13.48585 ? 1582 PRO A O    1 
ATOM   1815 C  CB   . PRO A 1 123 ? -2.89132  -20.86625 5.83651   1.000 13.03053 ? 1582 PRO A CB   1 
ATOM   1816 C  CG   . PRO A 1 123 ? -3.99759  -21.49818 6.66656   1.000 13.10948 ? 1582 PRO A CG   1 
ATOM   1817 C  CD   . PRO A 1 123 ? -5.16422  -20.52716 6.51711   1.000 12.02778 ? 1582 PRO A CD   1 
ATOM   1818 H  HA   . PRO A 1 123 ? -2.48498  -19.12271 6.84198   1.000 15.15306 ? 1582 PRO A HA   1 
ATOM   1819 H  HB2  . PRO A 1 123 ? -3.00680  -21.05927 4.89295   1.000 15.63943 ? 1582 PRO A HB2  1 
ATOM   1820 H  HB3  . PRO A 1 123 ? -2.01695  -21.16501 6.13168   1.000 15.63943 ? 1582 PRO A HB3  1 
ATOM   1821 H  HG2  . PRO A 1 123 ? -4.22239  -22.37380 6.31491   1.000 15.73418 ? 1582 PRO A HG2  1 
ATOM   1822 H  HG3  . PRO A 1 123 ? -3.72034  -21.57390 7.59301   1.000 15.73418 ? 1582 PRO A HG3  1 
ATOM   1823 H  HD2  . PRO A 1 123 ? -5.67530  -20.71911 5.71533   1.000 14.43613 ? 1582 PRO A HD2  1 
ATOM   1824 H  HD3  . PRO A 1 123 ? -5.74316  -20.55756 7.29480   1.000 14.43613 ? 1582 PRO A HD3  1 
ATOM   1825 N  N    . SER A 1 124 ? -1.54286  -17.83353 4.98200   1.000 15.08341 ? 1583 SER A N    1 
ATOM   1826 C  CA   . SER A 1 124 ? -1.22548  -16.78811 4.01600   1.000 17.64687 ? 1583 SER A CA   1 
ATOM   1827 C  C    . SER A 1 124 ? -0.91204  -17.33637 2.62870   1.000 16.56253 ? 1583 SER A C    1 
ATOM   1828 O  O    . SER A 1 124 ? -0.99123  -16.58344 1.65447   1.000 17.63634 ? 1583 SER A O    1 
ATOM   1829 C  CB   . SER A 1 124 ? -0.06216  -15.94312 4.53064   1.000 21.26309 ? 1583 SER A CB   1 
ATOM   1830 O  OG   . SER A 1 124 ? 1.10077   -16.73504 4.58432   1.000 23.10542 ? 1583 SER A OG   1 
ATOM   1831 H  H    . SER A 1 124 ? -0.94711  -17.95789 5.58963   1.000 18.10289 ? 1583 SER A H    1 
ATOM   1832 H  HA   . SER A 1 124 ? -1.99789  -16.20879 3.92291   1.000 21.17904 ? 1583 SER A HA   1 
ATOM   1833 H  HB2  . SER A 1 124 ? 0.08433   -15.19662 3.92883   1.000 25.51851 ? 1583 SER A HB2  1 
ATOM   1834 H  HB3  . SER A 1 124 ? -0.27038  -15.61643 5.41992   1.000 25.51851 ? 1583 SER A HB3  1 
ATOM   1835 H  HG   . SER A 1 124 ? 1.74786   -16.27680 4.86162   1.000 27.72930 ? 1583 SER A HG   1 
ATOM   1836 N  N    . HIS A 1 125 ? -0.56654  -18.62218 2.50808   1.000 14.93602 ? 1584 HIS A N    1 
ATOM   1837 C  CA   . HIS A 1 125 ? -0.26265  -19.21504 1.21567   1.000 14.47544 ? 1584 HIS A CA   1 
ATOM   1838 C  C    . HIS A 1 125 ? -1.49978  -19.73784 0.49540   1.000 12.67259 ? 1584 HIS A C    1 
ATOM   1839 O  O    . HIS A 1 125 ? -1.38767  -20.16836 -0.65478  1.000 13.67534 ? 1584 HIS A O    1 
ATOM   1840 C  CB   . HIS A 1 125 ? 0.76262   -20.35185 1.38033   1.000 15.04393 ? 1584 HIS A CB   1 
ATOM   1841 C  CG   . HIS A 1 125 ? 0.23945   -21.53547 2.13338   1.000 15.66506 ? 1584 HIS A CG   1 
ATOM   1842 N  ND1  . HIS A 1 125 ? -0.03324  -21.49766 3.48365   1.000 16.39146 ? 1584 HIS A ND1  1 
ATOM   1843 C  CD2  . HIS A 1 125 ? -0.08703  -22.78207 1.71935   1.000 16.23618 ? 1584 HIS A CD2  1 
ATOM   1844 C  CE1  . HIS A 1 125 ? -0.49823  -22.67581 3.87119   1.000 16.18880 ? 1584 HIS A CE1  1 
ATOM   1845 N  NE2  . HIS A 1 125 ? -0.54495  -23.47029 2.81833   1.000 16.08353 ? 1584 HIS A NE2  1 
ATOM   1846 H  H    . HIS A 1 125 ? -0.50263  -19.16958 3.16828   1.000 17.92602 ? 1584 HIS A H    1 
ATOM   1847 H  HA   . HIS A 1 125 ? 0.13923   -18.53518 0.65249   1.000 17.37332 ? 1584 HIS A HA   1 
ATOM   1848 H  HB2  . HIS A 1 125 ? 1.03286   -20.65738 0.50026   1.000 18.05551 ? 1584 HIS A HB2  1 
ATOM   1849 H  HB3  . HIS A 1 125 ? 1.53130   -20.01038 1.86348   1.000 18.05551 ? 1584 HIS A HB3  1 
ATOM   1850 H  HD1  . HIS A 1 125 ? 0.08071   -20.81557 3.99490   1.000 19.67255 ? 1584 HIS A HD1  1 
ATOM   1851 H  HD2  . HIS A 1 125 ? -0.01505  -23.11186 0.85277   1.000 19.48621 ? 1584 HIS A HD2  1 
ATOM   1852 H  HE1  . HIS A 1 125 ? -0.74894  -22.90415 4.73716   1.000 19.42936 ? 1584 HIS A HE1  1 
ATOM   1853 N  N    . LEU A 1 126 ? -2.66914  -19.69592 1.12580   1.000 10.70131 ? 1585 LEU A N    1 
ATOM   1854 C  CA   . LEU A 1 126 ? -3.84881  -20.30612 0.53625   1.000 10.78026 ? 1585 LEU A CA   1 
ATOM   1855 C  C    . LEU A 1 126 ? -4.75111  -19.25648 -0.08947  1.000 10.49865 ? 1585 LEU A C    1 
ATOM   1856 O  O    . LEU A 1 126 ? -4.78712  -18.09761 0.35108   1.000 11.80406 ? 1585 LEU A O    1 
ATOM   1857 C  CB   . LEU A 1 126 ? -4.63252  -21.10839 1.57771   1.000 11.50666 ? 1585 LEU A CB   1 
ATOM   1858 C  CG   . LEU A 1 126 ? -3.87700  -22.32352 2.14758   1.000 12.11726 ? 1585 LEU A CG   1 
ATOM   1859 C  CD1  . LEU A 1 126 ? -4.68940  -22.89237 3.28210   1.000 12.22780 ? 1585 LEU A CD1  1 
ATOM   1860 C  CD2  . LEU A 1 126 ? -3.57568  -23.37450 1.06962   1.000 12.57784 ? 1585 LEU A CD2  1 
ATOM   1861 H  H    . LEU A 1 126 ? -2.80179  -19.32278 1.88919   1.000 12.84437 ? 1585 LEU A H    1 
ATOM   1862 H  HA   . LEU A 1 126 ? -3.57518  -20.92059 -0.16265  1.000 12.93911 ? 1585 LEU A HA   1 
ATOM   1863 H  HB2  . LEU A 1 126 ? -4.84855  -20.52232 2.31984   1.000 13.81079 ? 1585 LEU A HB2  1 
ATOM   1864 H  HB3  . LEU A 1 126 ? -5.44724  -21.43590 1.16556   1.000 13.81079 ? 1585 LEU A HB3  1 
ATOM   1865 H  HG   . LEU A 1 126 ? -3.00882  -22.04909 2.48203   1.000 14.54351 ? 1585 LEU A HG   1 
ATOM   1866 H  HD11 . LEU A 1 126 ? -4.20961  -23.64097 3.66978   1.000 14.67616 ? 1585 LEU A HD11 1 
ATOM   1867 H  HD12 . LEU A 1 126 ? -4.82333  -22.20305 3.95128   1.000 14.67616 ? 1585 LEU A HD12 1 
ATOM   1868 H  HD13 . LEU A 1 126 ? -5.54605  -23.19074 2.93853   1.000 14.67616 ? 1585 LEU A HD13 1 
ATOM   1869 H  HD21 . LEU A 1 126 ? -3.21797  -24.16952 1.49493   1.000 15.09621 ? 1585 LEU A HD21 1 
ATOM   1870 H  HD22 . LEU A 1 126 ? -4.39708  -23.59102 0.60131   1.000 15.09621 ? 1585 LEU A HD22 1 
ATOM   1871 H  HD23 . LEU A 1 126 ? -2.92605  -23.01146 0.44746   1.000 15.09621 ? 1585 LEU A HD23 1 
ATOM   1872 N  N    . PRO A 1 127 ? -5.49978  -19.62071 -1.13159  1.000 10.46443 ? 1586 PRO A N    1 
ATOM   1873 C  CA   . PRO A 1 127 ? -6.28265  -18.60898 -1.84883  1.000 10.29599 ? 1586 PRO A CA   1 
ATOM   1874 C  C    . PRO A 1 127 ? -7.40160  -18.00647 -1.01507  1.000 10.08018 ? 1586 PRO A C    1 
ATOM   1875 O  O    . PRO A 1 127 ? -8.04414  -18.67117 -0.19295  1.000 10.51707 ? 1586 PRO A O    1 
ATOM   1876 C  CB   . PRO A 1 127 ? -6.85172  -19.39251 -3.04072  1.000 10.67762 ? 1586 PRO A CB   1 
ATOM   1877 C  CG   . PRO A 1 127 ? -5.93829  -20.58059 -3.18644  1.000 11.34085 ? 1586 PRO A CG   1 
ATOM   1878 C  CD   . PRO A 1 127 ? -5.51803  -20.92487 -1.82788  1.000 11.26453 ? 1586 PRO A CD   1 
ATOM   1879 H  HA   . PRO A 1 127 ? -5.69903  -17.89470 -2.14898  1.000 12.35799 ? 1586 PRO A HA   1 
ATOM   1880 H  HB2  . PRO A 1 127 ? -7.76041  -19.67302 -2.84967  1.000 12.81594 ? 1586 PRO A HB2  1 
ATOM   1881 H  HB3  . PRO A 1 127 ? -6.83560  -18.84074 -3.83834  1.000 12.81594 ? 1586 PRO A HB3  1 
ATOM   1882 H  HG2  . PRO A 1 127 ? -6.42038  -21.31674 -3.59457  1.000 13.61182 ? 1586 PRO A HG2  1 
ATOM   1883 H  HG3  . PRO A 1 127 ? -5.17357  -20.34118 -3.73305  1.000 13.61182 ? 1586 PRO A HG3  1 
ATOM   1884 H  HD2  . PRO A 1 127 ? -6.15430  -21.52806 -1.41290  1.000 13.52023 ? 1586 PRO A HD2  1 
ATOM   1885 H  HD3  . PRO A 1 127 ? -4.63474  -21.32573 -1.83171  1.000 13.52023 ? 1586 PRO A HD3  1 
ATOM   1886 N  N    . ILE A 1 128 ? -7.65639  -16.73051 -1.28592  1.000 9.75909  ? 1587 ILE A N    1 
ATOM   1887 C  CA   A ILE A 1 128 ? -8.84098  -16.02782 -0.81816  0.039 9.50905  ? 1587 ILE A CA   1 
ATOM   1888 C  CA   B ILE A 1 128 ? -8.83641  -16.01947 -0.81744  0.961 9.77224  ? 1587 ILE A CA   1 
ATOM   1889 C  C    . ILE A 1 128 ? -9.50306  -15.39410 -2.03186  1.000 9.42483  ? 1587 ILE A C    1 
ATOM   1890 O  O    . ILE A 1 128 ? -8.84783  -14.67691 -2.80439  1.000 9.98016  ? 1587 ILE A O    1 
ATOM   1891 C  CB   A ILE A 1 128 ? -8.49818  -14.96014 0.23765   0.039 9.42483  ? 1587 ILE A CB   1 
ATOM   1892 C  CB   B ILE A 1 128 ? -8.50213  -14.91737 0.20683   0.961 10.45127 ? 1587 ILE A CB   1 
ATOM   1893 C  CG1  A ILE A 1 128 ? -7.78900  -15.61220 1.42783   0.039 9.41431  ? 1587 ILE A CG1  1 
ATOM   1894 C  CG1  B ILE A 1 128 ? -7.90908  -15.49168 1.49103   0.961 11.33033 ? 1587 ILE A CG1  1 
ATOM   1895 C  CG2  A ILE A 1 128 ? -9.75981  -14.23905 0.69512   0.039 9.44063  ? 1587 ILE A CG2  1 
ATOM   1896 C  CG2  B ILE A 1 128 ? -9.77552  -14.09679 0.51180   0.961 11.47245 ? 1587 ILE A CG2  1 
ATOM   1897 C  CD1  A ILE A 1 128 ? -7.41770  -14.64955 2.53754   0.039 9.41957  ? 1587 ILE A CD1  1 
ATOM   1898 C  CD1  B ILE A 1 128 ? -7.57404  -14.45329 2.54949   0.961 12.14884 ? 1587 ILE A CD1  1 
ATOM   1899 H  H    A ILE A 1 128 ? -7.13619  -16.23373 -1.75730  0.039 11.71370 ? 1587 ILE A H    1 
ATOM   1900 H  H    B ILE A 1 128 ? -7.13652  -16.23600 -1.76004  0.961 11.71370 ? 1587 ILE A H    1 
ATOM   1901 H  HA   A ILE A 1 128 ? -9.45992  -16.65585 -0.41393  0.039 11.41366 ? 1587 ILE A HA   1 
ATOM   1902 H  HA   B ILE A 1 128 ? -9.43712  -16.65296 -0.39467  0.961 11.72949 ? 1587 ILE A HA   1 
ATOM   1903 H  HB   A ILE A 1 128 ? -7.90195  -14.30766 -0.16194  0.039 11.31260 ? 1587 ILE A HB   1 
ATOM   1904 H  HB   B ILE A 1 128 ? -7.82650  -14.34015 -0.18205  0.961 12.54433 ? 1587 ILE A HB   1 
ATOM   1905 H  HG12 A ILE A 1 128 ? -8.37570  -16.28515 1.80706   0.039 11.29996 ? 1587 ILE A HG12 1 
ATOM   1906 H  HG12 B ILE A 1 128 ? -8.54957  -16.10868 1.87832   0.961 13.59919 ? 1587 ILE A HG12 1 
ATOM   1907 H  HG13 A ILE A 1 128 ? -6.97043  -16.02572 1.11184   0.039 11.29996 ? 1587 ILE A HG13 1 
ATOM   1908 H  HG13 B ILE A 1 128 ? -7.08890  -15.96012 1.27022   0.961 13.59919 ? 1587 ILE A HG13 1 
ATOM   1909 H  HG21 A ILE A 1 128 ? -9.51946  -13.57002 1.35507   0.039 11.33155 ? 1587 ILE A HG21 1 
ATOM   1910 H  HG21 B ILE A 1 128 ? -9.60024  -13.50953 1.26367   0.961 13.76973 ? 1587 ILE A HG21 1 
ATOM   1911 H  HG22 A ILE A 1 128 ? -10.17573 -13.81354 -0.07094  0.039 11.33155 ? 1587 ILE A HG22 1 
ATOM   1912 H  HG22 B ILE A 1 128 ? -10.00810 -13.57234 -0.27035  0.961 13.76973 ? 1587 ILE A HG22 1 
ATOM   1913 H  HG23 A ILE A 1 128 ? -10.36880 -14.88515 1.08573   0.039 11.33155 ? 1587 ILE A HG23 1 
ATOM   1914 H  HG23 B ILE A 1 128 ? -10.49891 -14.70540 0.72905   0.961 13.76973 ? 1587 ILE A HG23 1 
ATOM   1915 H  HD11 A ILE A 1 128 ? -6.80271  -15.08979 3.14489   0.039 11.30628 ? 1587 ILE A HD11 1 
ATOM   1916 H  HD11 B ILE A 1 128 ? -6.95445  -14.84097 3.18724   0.961 14.58141 ? 1587 ILE A HD11 1 
ATOM   1917 H  HD12 A ILE A 1 128 ? -6.99575  -13.86731 2.14901   0.039 11.30628 ? 1587 ILE A HD12 1 
ATOM   1918 H  HD12 B ILE A 1 128 ? -7.16839  -13.68400 2.11992   0.961 14.58141 ? 1587 ILE A HD12 1 
ATOM   1919 H  HD13 A ILE A 1 128 ? -8.22250  -14.38965 3.01257   0.039 11.30628 ? 1587 ILE A HD13 1 
ATOM   1920 H  HD13 B ILE A 1 128 ? -8.39047  -14.18776 3.00097   0.961 14.58141 ? 1587 ILE A HD13 1 
ATOM   1921 N  N    . VAL A 1 129 ? -10.79933 -15.63960 -2.19238  1.000 9.19586  ? 1588 VAL A N    1 
ATOM   1922 C  CA   . VAL A 1 129 ? -11.57276 -15.02395 -3.25947  1.000 9.38272  ? 1588 VAL A CA   1 
ATOM   1923 C  C    . VAL A 1 129 ? -12.72510 -14.26664 -2.63060  1.000 8.82213  ? 1588 VAL A C    1 
ATOM   1924 O  O    . VAL A 1 129 ? -13.19808 -14.61514 -1.54533  1.000 9.83541  ? 1588 VAL A O    1 
ATOM   1925 C  CB   . VAL A 1 129 ? -12.08101 -16.04242 -4.30302  1.000 10.36968 ? 1588 VAL A CB   1 
ATOM   1926 C  CG1  . VAL A 1 129 ? -10.94675 -16.93799 -4.74599  1.000 10.91185 ? 1588 VAL A CG1  1 
ATOM   1927 C  CG2  . VAL A 1 129 ? -13.20222 -16.89986 -3.76939  1.000 11.81722 ? 1588 VAL A CG2  1 
ATOM   1928 H  H    . VAL A 1 129 ? -11.25643 -16.16583 -1.68865  1.000 11.03783 ? 1588 VAL A H    1 
ATOM   1929 H  HA   . VAL A 1 129 ? -11.00658 -14.39467 -3.73313  1.000 11.26207 ? 1588 VAL A HA   1 
ATOM   1930 H  HB   . VAL A 1 129 ? -12.42538 -15.53752 -5.05628  1.000 12.44642 ? 1588 VAL A HB   1 
ATOM   1931 H  HG11 . VAL A 1 129 ? -11.14733 -17.28889 -5.62777  1.000 13.09702 ? 1588 VAL A HG11 1 
ATOM   1932 H  HG12 . VAL A 1 129 ? -10.12761 -16.41926 -4.77488  1.000 13.09702 ? 1588 VAL A HG12 1 
ATOM   1933 H  HG13 . VAL A 1 129 ? -10.85439 -17.66713 -4.11297  1.000 13.09702 ? 1588 VAL A HG13 1 
ATOM   1934 H  HG21 . VAL A 1 129 ? -13.32800 -17.65883 -4.36018  1.000 14.18347 ? 1588 VAL A HG21 1 
ATOM   1935 H  HG22 . VAL A 1 129 ? -12.96813 -17.20821 -2.87999  1.000 14.18347 ? 1588 VAL A HG22 1 
ATOM   1936 H  HG23 . VAL A 1 129 ? -14.01446 -16.37086 -3.73296  1.000 14.18347 ? 1588 VAL A HG23 1 
ATOM   1937 N  N    . ALA A 1 130 ? -13.18354 -13.22018 -3.31512  1.000 9.14322  ? 1589 ALA A N    1 
ATOM   1938 C  CA   . ALA A 1 130 ? -14.24941 -12.40695 -2.75118  1.000 9.04058  ? 1589 ALA A CA   1 
ATOM   1939 C  C    . ALA A 1 130 ? -15.31591 -12.04216 -3.76621  1.000 8.90109  ? 1589 ALA A C    1 
ATOM   1940 O  O    . ALA A 1 130 ? -15.01744 -11.64339 -4.89168  1.000 9.40641  ? 1589 ALA A O    1 
ATOM   1941 C  CB   . ALA A 1 130 ? -13.68691 -11.09936 -2.16780  1.000 10.18808 ? 1589 ALA A CB   1 
ATOM   1942 H  H    . ALA A 1 130 ? -12.89848 -12.97079 -4.08722  1.000 10.97466 ? 1589 ALA A H    1 
ATOM   1943 H  HA   . ALA A 1 130 ? -14.68108 -12.94325 -2.06786  1.000 10.85149 ? 1589 ALA A HA   1 
ATOM   1944 H  HB1  . ALA A 1 130 ? -14.41851 -10.57332 -1.80872  1.000 12.22850 ? 1589 ALA A HB1  1 
ATOM   1945 H  HB2  . ALA A 1 130 ? -13.05634 -11.31372 -1.46258  1.000 12.22850 ? 1589 ALA A HB2  1 
ATOM   1946 H  HB3  . ALA A 1 130 ? -13.23946 -10.60576 -2.87282  1.000 12.22850 ? 1589 ALA A HB3  1 
ATOM   1947 N  N    . HIS A 1 131 ? -16.57708 -12.13100 -3.31604  1.000 9.23271  ? 1590 HIS A N    1 
ATOM   1948 C  CA   . HIS A 1 131 ? -17.69415 -11.46336 -3.97365  1.000 9.50379  ? 1590 HIS A CA   1 
ATOM   1949 C  C    . HIS A 1 131 ? -17.65778 -10.02671 -3.46926  1.000 9.26692  ? 1590 HIS A C    1 
ATOM   1950 O  O    . HIS A 1 131 ? -17.91674 -9.77499  -2.28801  1.000 10.25914 ? 1590 HIS A O    1 
ATOM   1951 C  CB   . HIS A 1 131 ? -19.02658 -12.11655 -3.61974  1.000 9.89068  ? 1590 HIS A CB   1 
ATOM   1952 C  CG   . HIS A 1 131 ? -20.17487 -11.52031 -4.36394  1.000 9.79857  ? 1590 HIS A CG   1 
ATOM   1953 N  ND1  . HIS A 1 131 ? -21.02344 -12.24693 -5.16651  1.000 10.19598 ? 1590 HIS A ND1  1 
ATOM   1954 C  CD2  . HIS A 1 131 ? -20.57681 -10.22790 -4.47947  1.000 10.79868 ? 1590 HIS A CD2  1 
ATOM   1955 C  CE1  . HIS A 1 131 ? -21.91468 -11.44247 -5.72247  1.000 10.18282 ? 1590 HIS A CE1  1 
ATOM   1956 N  NE2  . HIS A 1 131 ? -21.65674 -10.21004 -5.32928  1.000 10.91712 ? 1590 HIS A NE2  1 
ATOM   1957 H  H    . HIS A 1 131 ? -16.80780 -12.58068 -2.62022  1.000 11.08204 ? 1590 HIS A H    1 
ATOM   1958 H  HA   . HIS A 1 131 ? -17.60365 -11.51050 -4.93827  1.000 11.40735 ? 1590 HIS A HA   1 
ATOM   1959 H  HB2  . HIS A 1 131 ? -18.98392 -13.06054 -3.83873  1.000 11.87161 ? 1590 HIS A HB2  1 
ATOM   1960 H  HB3  . HIS A 1 131 ? -19.19196 -12.00329 -2.67068  1.000 11.87161 ? 1590 HIS A HB3  1 
ATOM   1961 H  HD2  . HIS A 1 131 ? -20.19245 -9.49163  -4.06106  1.000 12.96122 ? 1590 HIS A HD2  1 
ATOM   1962 H  HE1  . HIS A 1 131 ? -22.60331 -11.70098 -6.29156  1.000 12.22218 ? 1590 HIS A HE1  1 
ATOM   1963 H  HE2  . HIS A 1 131 ? -22.09389 -9.50844  -5.56648  1.000 13.10334 ? 1590 HIS A HE2  1 
ATOM   1964 N  N    . ALA A 1 132 ? -17.21115 -9.11148  -4.33822  1.000 9.16691  ? 1591 ALA A N    1 
ATOM   1965 C  CA   . ALA A 1 132 ? -16.87688 -7.74068  -3.93610  1.000 9.88542  ? 1591 ALA A CA   1 
ATOM   1966 C  C    . ALA A 1 132 ? -17.20185 -6.81185  -5.10006  1.000 11.26190 ? 1591 ALA A C    1 
ATOM   1967 O  O    . ALA A 1 132 ? -16.42085 -6.68539  -6.04601  1.000 13.83325 ? 1591 ALA A O    1 
ATOM   1968 C  CB   . ALA A 1 132 ? -15.41028 -7.65647  -3.55014  1.000 9.99069  ? 1591 ALA A CB   1 
ATOM   1969 H  H    . ALA A 1 132 ? -17.09191 -9.26221  -5.17647  1.000 11.00309 ? 1591 ALA A H    1 
ATOM   1970 H  HA   . ALA A 1 132 ? -17.42745 -7.47664  -3.18241  1.000 11.86530 ? 1591 ALA A HA   1 
ATOM   1971 H  HB1  . ALA A 1 132 ? -15.20777 -6.74865  -3.27492  1.000 11.99163 ? 1591 ALA A HB1  1 
ATOM   1972 H  HB2  . ALA A 1 132 ? -15.24069 -8.26971  -2.81796  1.000 11.99163 ? 1591 ALA A HB2  1 
ATOM   1973 H  HB3  . ALA A 1 132 ? -14.86756 -7.89854  -4.31680  1.000 11.99163 ? 1591 ALA A HB3  1 
ATOM   1974 N  N    . GLU A 1 133 ? -18.32147 -6.12359  -5.00103  1.000 10.88554 ? 1592 GLU A N    1 
ATOM   1975 C  CA   . GLU A 1 133 ? -18.78592 -5.29793  -6.09816  1.000 10.64603 ? 1592 GLU A CA   1 
ATOM   1976 C  C    . GLU A 1 133 ? -18.51634 -3.82195  -5.83015  1.000 10.38811 ? 1592 GLU A C    1 
ATOM   1977 O  O    . GLU A 1 133 ? -18.60186 -3.35449  -4.69468  1.000 10.45917 ? 1592 GLU A O    1 
ATOM   1978 C  CB   . GLU A 1 133 ? -20.28903 -5.47350  -6.25916  1.000 11.04608 ? 1592 GLU A CB   1 
ATOM   1979 C  CG   . GLU A 1 133 ? -20.68461 -6.88665  -6.59002  1.000 11.52509 ? 1592 GLU A CG   1 
ATOM   1980 C  CD   . GLU A 1 133 ? -22.16484 -7.01743  -6.90784  1.000 12.53310 ? 1592 GLU A CD   1 
ATOM   1981 O  OE1  . GLU A 1 133 ? -22.68012 -6.15123  -7.66123  1.000 13.23055 ? 1592 GLU A OE1  1 
ATOM   1982 O  OE2  . GLU A 1 133 ? -22.80459 -7.97699  -6.39272  1.000 13.68587 ? 1592 GLU A OE2  1 
ATOM   1983 H  H    . GLU A 1 133 ? -18.83074 -6.11800  -4.30805  1.000 13.06544 ? 1592 GLU A H    1 
ATOM   1984 H  HA   . GLU A 1 133 ? -18.31848 -5.55490  -6.90832  1.000 12.77804 ? 1592 GLU A HA   1 
ATOM   1985 H  HB2  . GLU A 1 133 ? -20.72525 -5.22739  -5.42846  1.000 13.25810 ? 1592 GLU A HB2  1 
ATOM   1986 H  HB3  . GLU A 1 133 ? -20.59745 -4.90029  -6.97833  1.000 13.25810 ? 1592 GLU A HB3  1 
ATOM   1987 H  HG2  . GLU A 1 133 ? -20.18297 -7.18295  -7.36556  1.000 13.83290 ? 1592 GLU A HG2  1 
ATOM   1988 H  HG3  . GLU A 1 133 ? -20.48841 -7.45692  -5.83029  1.000 13.83290 ? 1592 GLU A HG3  1 
ATOM   1989 N  N    . GLN A 1 134 ? -18.24065 -3.08450  -6.91316  1.000 11.62773 ? 1593 GLN A N    1 
ATOM   1990 C  CA   . GLN A 1 134 ? -18.11463 -1.62191  -6.87529  1.000 11.64353 ? 1593 GLN A CA   1 
ATOM   1991 C  C    . GLN A 1 134 ? -17.10611 -1.21863  -5.81246  1.000 12.33312 ? 1593 GLN A C    1 
ATOM   1992 O  O    . GLN A 1 134 ? -15.97637 -1.71475  -5.83026  1.000 11.98304 ? 1593 GLN A O    1 
ATOM   1993 C  CB   . GLN A 1 134 ? -19.46939 -0.93320  -6.81365  1.000 13.34372 ? 1593 GLN A CB   1 
ATOM   1994 C  CG   . GLN A 1 134 ? -20.41825 -1.41394  -7.79925  1.000 14.90970 ? 1593 GLN A CG   1 
ATOM   1995 C  CD   . GLN A 1 134 ? -21.61453 -0.48900  -7.91911  1.000 16.60727 ? 1593 GLN A CD   1 
ATOM   1996 O  OE1  . GLN A 1 134 ? -22.68868 -0.86489  -7.47160  1.000 17.51528 ? 1593 GLN A OE1  1 
ATOM   1997 N  NE2  . GLN A 1 134 ? -21.46389 0.66764   -8.56224  1.000 17.79952 ? 1593 GLN A NE2  1 
ATOM   1998 H  H    . GLN A 1 134 ? -18.11993 -3.41626  -7.69736  1.000 13.95607 ? 1593 GLN A H    1 
ATOM   1999 H  HA   . GLN A 1 134 ? -17.71838 -1.37793  -7.72638  1.000 13.97503 ? 1593 GLN A HA   1 
ATOM   2000 H  HB2  . GLN A 1 134 ? -19.85436 -1.08169  -5.93578  1.000 16.01527 ? 1593 GLN A HB2  1 
ATOM   2001 H  HB3  . GLN A 1 134 ? -19.34278 0.01667   -6.96403  1.000 16.01527 ? 1593 GLN A HB3  1 
ATOM   2002 H  HG2  . GLN A 1 134 ? -19.98362 -1.46415  -8.66497  1.000 17.89444 ? 1593 GLN A HG2  1 
ATOM   2003 H  HG3  . GLN A 1 134 ? -20.73657 -2.29173  -7.53643  1.000 17.89444 ? 1593 GLN A HG3  1 
ATOM   2004 H  HE21 . GLN A 1 134 ? -20.70047 0.87626   -8.89879  1.000 21.36222 ? 1593 GLN A HE21 1 
ATOM   2005 H  HE22 . GLN A 1 134 ? -22.13005 1.20582   -8.64094  1.000 21.36222 ? 1593 GLN A HE22 1 
ATOM   2006 N  N    . GLN A 1 135 ? -17.44809 -0.31785  -4.89210  1.000 29.51667 ? 1594 GLN A N    1 
ATOM   2007 C  CA   . GLN A 1 135 ? -16.44162 0.13098   -3.94179  1.000 30.03783 ? 1594 GLN A CA   1 
ATOM   2008 C  C    . GLN A 1 135 ? -15.91789 -1.00063  -3.06709  1.000 29.51931 ? 1594 GLN A C    1 
ATOM   2009 O  O    . GLN A 1 135 ? -14.83357 -0.87008  -2.50079  1.000 30.01677 ? 1594 GLN A O    1 
ATOM   2010 C  CB   . GLN A 1 135 ? -16.98439 1.26572   -3.09271  1.000 30.05362 ? 1594 GLN A CB   1 
ATOM   2011 C  CG   . GLN A 1 135 ? -18.05011 0.88801   -2.13488  1.000 30.06678 ? 1594 GLN A CG   1 
ATOM   2012 C  CD   . GLN A 1 135 ? -18.50247 2.11980   -1.34623  1.000 30.06415 ? 1594 GLN A CD   1 
ATOM   2013 O  OE1  . GLN A 1 135 ? -18.00401 2.38459   -0.27748  1.000 30.04573 ? 1594 GLN A OE1  1 
ATOM   2014 N  NE2  . GLN A 1 135 ? -19.41919 2.89265   -1.91663  1.000 30.07205 ? 1594 GLN A NE2  1 
ATOM   2015 H  H    . GLN A 1 135 ? -18.22757 0.03420   -4.80224  1.000 35.42280 ? 1594 GLN A H    1 
ATOM   2016 H  HA   . GLN A 1 135 ? -15.68461 0.48133   -4.43684  1.000 36.04819 ? 1594 GLN A HA   1 
ATOM   2017 H  HB2  . GLN A 1 135 ? -16.25209 1.63957   -2.57805  1.000 36.06714 ? 1594 GLN A HB2  1 
ATOM   2018 H  HB3  . GLN A 1 135 ? -17.35281 1.94064   -3.68403  1.000 36.06714 ? 1594 GLN A HB3  1 
ATOM   2019 H  HG2  . GLN A 1 135 ? -18.81145 0.52964   -2.61740  1.000 36.08294 ? 1594 GLN A HG2  1 
ATOM   2020 H  HG3  . GLN A 1 135 ? -17.71061 0.22629   -1.51217  1.000 36.08294 ? 1594 GLN A HG3  1 
ATOM   2021 H  HE21 . GLN A 1 135 ? -19.72934 2.69060   -2.69289  1.000 36.08925 ? 1594 GLN A HE21 1 
ATOM   2022 H  HE22 . GLN A 1 135 ? -19.70279 3.59526   -1.50982  1.000 36.08925 ? 1594 GLN A HE22 1 
ATOM   2023 N  N    . THR A 1 136 ? -16.65623 -2.10813  -2.95512  1.000 11.08560 ? 1595 THR A N    1 
ATOM   2024 C  CA   . THR A 1 136 ? -16.18900 -3.23235  -2.15803  1.000 10.58024 ? 1595 THR A CA   1 
ATOM   2025 C  C    . THR A 1 136 ? -14.90118 -3.81836  -2.72819  1.000 10.10913 ? 1595 THR A C    1 
ATOM   2026 O  O    . THR A 1 136 ? -14.07938 -4.36179  -1.97242  1.000 10.54865 ? 1595 THR A O    1 
ATOM   2027 C  CB   . THR A 1 136 ? -17.28480 -4.29999  -2.08117  1.000 10.67762 ? 1595 THR A CB   1 
ATOM   2028 O  OG1  . THR A 1 136 ? -18.53508 -3.68193  -1.71561  1.000 10.96712 ? 1595 THR A OG1  1 
ATOM   2029 C  CG2  . THR A 1 136 ? -16.96180 -5.35651  -1.04083  1.000 11.05661 ? 1595 THR A CG2  1 
ATOM   2030 H  H    . THR A 1 136 ? -17.42183 -2.22864  -3.32785  1.000 13.30552 ? 1595 THR A H    1 
ATOM   2031 H  HA   . THR A 1 136 ? -16.00220 -2.93147  -1.25499  1.000 12.69908 ? 1595 THR A HA   1 
ATOM   2032 H  HB   . THR A 1 136 ? -17.35442 -4.73032  -2.94770  1.000 12.81594 ? 1595 THR A HB   1 
ATOM   2033 H  HG1  . THR A 1 136 ? -18.79606 -3.17486  -2.33235  1.000 13.16335 ? 1595 THR A HG1  1 
ATOM   2034 H  HG21 . THR A 1 136 ? -17.69354 -5.98959  -0.97265  1.000 13.27073 ? 1595 THR A HG21 1 
ATOM   2035 H  HG22 . THR A 1 136 ? -16.15525 -5.83344  -1.29167  1.000 13.27073 ? 1595 THR A HG22 1 
ATOM   2036 H  HG23 . THR A 1 136 ? -16.82476 -4.93941  -0.17588  1.000 13.27073 ? 1595 THR A HG23 1 
ATOM   2037 N  N    . VAL A 1 137 ? -14.67571 -3.69598  -4.03436  1.000 10.40390 ? 1596 VAL A N    1 
ATOM   2038 C  CA   A VAL A 1 137 ? -13.40829 -4.16624  -4.58162  0.328 10.36442 ? 1596 VAL A CA   1 
ATOM   2039 C  CA   B VAL A 1 137 ? -13.40303 -4.12712  -4.62218  0.672 10.66972 ? 1596 VAL A CA   1 
ATOM   2040 C  C    . VAL A 1 137 ? -12.25152 -3.35398  -4.01055  1.000 10.36179 ? 1596 VAL A C    1 
ATOM   2041 O  O    . VAL A 1 137 ? -11.23354 -3.90899  -3.60127  1.000 10.40916 ? 1596 VAL A O    1 
ATOM   2042 C  CB   A VAL A 1 137 ? -13.45063 -4.20753  -6.11908  0.328 10.48022 ? 1596 VAL A CB   1 
ATOM   2043 C  CB   B VAL A 1 137 ? -13.41486 -3.95805  -6.14700  0.672 11.51456 ? 1596 VAL A CB   1 
ATOM   2044 C  CG1  A VAL A 1 137 ? -13.16602 -2.86143  -6.71404  0.328 10.78026 ? 1596 VAL A CG1  1 
ATOM   2045 C  CG1  B VAL A 1 137 ? -12.03951 -4.31646  -6.70769  0.672 12.10673 ? 1596 VAL A CG1  1 
ATOM   2046 C  CG2  A VAL A 1 137 ? -12.47013 -5.25704  -6.63353  0.328 10.59866 ? 1596 VAL A CG2  1 
ATOM   2047 C  CG2  B VAL A 1 137 ? -14.46303 -4.81653  -6.77730  0.672 11.38296 ? 1596 VAL A CG2  1 
ATOM   2048 H  H    A VAL A 1 137 ? -15.22163 -3.35593  -4.60527  0.328 12.48748 ? 1596 VAL A H    1 
ATOM   2049 H  H    B VAL A 1 137 ? -15.23558 -3.37002  -4.59995  0.672 12.48748 ? 1596 VAL A H    1 
ATOM   2050 H  HA   A VAL A 1 137 ? -13.26188 -5.08295  -4.30038  0.328 12.44010 ? 1596 VAL A HA   1 
ATOM   2051 H  HA   B VAL A 1 137 ? -13.28944 -5.06942  -4.42201  0.672 12.80646 ? 1596 VAL A HA   1 
ATOM   2052 H  HB   A VAL A 1 137 ? -14.34513 -4.45407  -6.40188  0.328 12.57907 ? 1596 VAL A HB   1 
ATOM   2053 H  HB   B VAL A 1 137 ? -13.62211 -3.03462  -6.35968  0.672 13.82027 ? 1596 VAL A HB   1 
ATOM   2054 H  HG11 A VAL A 1 137 ? -13.41349 -2.87195  -7.65188  0.328 12.93911 ? 1596 VAL A HG11 1 
ATOM   2055 H  HG11 B VAL A 1 137 ? -12.11294 -4.44477  -7.66636  0.672 14.53088 ? 1596 VAL A HG11 1 
ATOM   2056 H  HG12 A VAL A 1 137 ? -13.68533 -2.19151  -6.24241  0.328 12.93911 ? 1596 VAL A HG12 1 
ATOM   2057 H  HG12 B VAL A 1 137 ? -11.42241 -3.59275  -6.51713  0.672 14.53088 ? 1596 VAL A HG12 1 
ATOM   2058 H  HG13 A VAL A 1 137 ? -12.21938 -2.67005  -6.62385  0.328 12.93911 ? 1596 VAL A HG13 1 
ATOM   2059 H  HG13 B VAL A 1 137 ? -11.73037 -5.13411  -6.28724  0.672 14.53088 ? 1596 VAL A HG13 1 
ATOM   2060 H  HG21 A VAL A 1 137 ? -12.49561 -5.26461  -7.60317  0.328 12.72119 ? 1596 VAL A HG21 1 
ATOM   2061 H  HG21 B VAL A 1 137 ? -14.50920 -4.61418  -7.72483  0.672 13.66235 ? 1596 VAL A HG21 1 
ATOM   2062 H  HG22 A VAL A 1 137 ? -11.57749 -5.03201  -6.32784  0.328 12.72119 ? 1596 VAL A HG22 1 
ATOM   2063 H  HG22 B VAL A 1 137 ? -14.22687 -5.74859  -6.64924  0.672 13.66235 ? 1596 VAL A HG22 1 
ATOM   2064 H  HG23 A VAL A 1 137 ? -12.72842 -6.12625  -6.28906  0.328 12.72119 ? 1596 VAL A HG23 1 
ATOM   2065 H  HG23 B VAL A 1 137 ? -15.31757 -4.63113  -6.35744  0.672 13.66235 ? 1596 VAL A HG23 1 
ATOM   2066 N  N    . ALA A 1 138 ? -12.39363 -2.02706  -3.96932  1.000 10.70393 ? 1597 ALA A N    1 
ATOM   2067 C  CA   . ALA A 1 138 ? -11.36416 -1.17661  -3.38018  1.000 10.05386 ? 1597 ALA A CA   1 
ATOM   2068 C  C    . ALA A 1 138 ? -11.20382 -1.47270  -1.89770  1.000 9.68539  ? 1597 ALA A C    1 
ATOM   2069 O  O    . ALA A 1 138 ? -10.08904 -1.50358  -1.37594  1.000 10.13018 ? 1597 ALA A O    1 
ATOM   2070 C  CB   . ALA A 1 138 ? -11.72596 0.29939   -3.60943  1.000 10.63024 ? 1597 ALA A CB   1 
ATOM   2071 H  H    . ALA A 1 138 ? -13.07363 -1.59796  -4.27438  1.000 12.84752 ? 1597 ALA A H    1 
ATOM   2072 H  HA   . ALA A 1 138 ? -10.51285 -1.34801  -3.81237  1.000 12.06743 ? 1597 ALA A HA   1 
ATOM   2073 H  HB1  . ALA A 1 138 ? -11.03193 0.85794   -3.22572  1.000 12.75909 ? 1597 ALA A HB1  1 
ATOM   2074 H  HB2  . ALA A 1 138 ? -11.79320 0.46362   -4.56306  1.000 12.75909 ? 1597 ALA A HB2  1 
ATOM   2075 H  HB3  . ALA A 1 138 ? -12.57579 0.48647   -3.18083  1.000 12.75909 ? 1597 ALA A HB3  1 
ATOM   2076 N  N    . ALA A 1 139 ? -12.31457 -1.67985  -1.18622  1.000 9.59064  ? 1598 ALA A N    1 
ATOM   2077 C  CA   . ALA A 1 139 ? -12.24636 -1.94669  0.24154   1.000 9.46958  ? 1598 ALA A CA   1 
ATOM   2078 C  C    . ALA A 1 139 ? -11.49493 -3.24581  0.52530   1.000 9.35114  ? 1598 ALA A C    1 
ATOM   2079 O  O    . ALA A 1 139 ? -10.64328 -3.29309  1.41888   1.000 10.02227 ? 1598 ALA A O    1 
ATOM   2080 C  CB   . ALA A 1 139 ? -13.64876 -1.99204  0.84547   1.000 9.89594  ? 1598 ALA A CB   1 
ATOM   2081 H  H    . ALA A 1 139 ? -13.11205 -1.67039  -1.50801  1.000 11.51157 ? 1598 ALA A H    1 
ATOM   2082 H  HA   . ALA A 1 139 ? -11.76459 -1.21949  0.66578   1.000 11.36629 ? 1598 ALA A HA   1 
ATOM   2083 H  HB1  . ALA A 1 139 ? -13.57766 -2.17305  1.79578   1.000 11.87793 ? 1598 ALA A HB1  1 
ATOM   2084 H  HB2  . ALA A 1 139 ? -14.08166 -1.13571  0.70333   1.000 11.87793 ? 1598 ALA A HB2  1 
ATOM   2085 H  HB3  . ALA A 1 139 ? -14.15674 -2.69550  0.41186   1.000 11.87793 ? 1598 ALA A HB3  1 
ATOM   2086 N  N    . VAL A 1 140 ? -11.81485 -4.32014  -0.21125  1.000 9.10901  ? 1599 VAL A N    1 
ATOM   2087 C  CA   . VAL A 1 140 ? -11.13726 -5.58173  0.08413   1.000 9.15112  ? 1599 VAL A CA   1 
ATOM   2088 C  C    . VAL A 1 140 ? -9.67344  -5.52423  -0.34457  1.000 9.07743  ? 1599 VAL A C    1 
ATOM   2089 O  O    . VAL A 1 140 ? -8.81399  -6.13110  0.30648   1.000 10.19598 ? 1599 VAL A O    1 
ATOM   2090 C  CB   . VAL A 1 140 ? -11.88111 -6.81229  -0.48423  1.000 9.66434  ? 1599 VAL A CB   1 
ATOM   2091 C  CG1  . VAL A 1 140 ? -11.73782 -6.92292  -1.99980  1.000 9.93542  ? 1599 VAL A CG1  1 
ATOM   2092 C  CG2  . VAL A 1 140 ? -11.39839 -8.12151  0.21762   1.000 9.96174  ? 1599 VAL A CG2  1 
ATOM   2093 H  H    . VAL A 1 140 ? -12.38913 -4.34029  -0.85110  1.000 10.93361 ? 1599 VAL A H    1 
ATOM   2094 H  HA   . VAL A 1 140 ? -11.15993 -5.69627  1.04707   1.000 10.98414 ? 1599 VAL A HA   1 
ATOM   2095 H  HB   . VAL A 1 140 ? -12.82620 -6.69581  -0.29945  1.000 11.60000 ? 1599 VAL A HB   1 
ATOM   2096 H  HG11 . VAL A 1 140 ? -12.61328 -7.07284  -2.38967  1.000 11.92530 ? 1599 VAL A HG11 1 
ATOM   2097 H  HG12 . VAL A 1 140 ? -11.36006 -6.09778  -2.34236  1.000 11.92530 ? 1599 VAL A HG12 1 
ATOM   2098 H  HG13 . VAL A 1 140 ? -11.15118 -7.66681  -2.20808  1.000 11.92530 ? 1599 VAL A HG13 1 
ATOM   2099 H  HG21 . VAL A 1 140 ? -11.88470 -8.87536  -0.15132  1.000 11.95689 ? 1599 VAL A HG21 1 
ATOM   2100 H  HG22 . VAL A 1 140 ? -10.44767 -8.23214  0.06017   1.000 11.95689 ? 1599 VAL A HG22 1 
ATOM   2101 H  HG23 . VAL A 1 140 ? -11.57001 -8.05114  1.16972   1.000 11.95689 ? 1599 VAL A HG23 1 
ATOM   2102 N  N    . LEU A 1 141 ? -9.36480  -4.78612  -1.41098  1.000 9.36430  ? 1600 LEU A N    1 
ATOM   2103 C  CA   . LEU A 1 141 ? -7.96376  -4.58065  -1.77927  1.000 9.89858  ? 1600 LEU A CA   1 
ATOM   2104 C  C    . LEU A 1 141 ? -7.21598  -3.87727  -0.65624  1.000 10.14597 ? 1600 LEU A C    1 
ATOM   2105 O  O    . LEU A 1 141 ? -6.06327  -4.20755  -0.36094  1.000 10.40916 ? 1600 LEU A O    1 
ATOM   2106 C  CB   . LEU A 1 141 ? -7.90259  -3.79059  -3.07385  1.000 10.93555 ? 1600 LEU A CB   1 
ATOM   2107 C  CG   . LEU A 1 141 ? -7.98723  -4.54752  -4.39124  1.000 14.74389 ? 1600 LEU A CG   1 
ATOM   2108 C  CD1  . LEU A 1 141 ? -8.10451  -3.65570  -5.60065  1.000 16.50726 ? 1600 LEU A CD1  1 
ATOM   2109 C  CD2  . LEU A 1 141 ? -6.77527  -5.50366  -4.47909  1.000 16.67307 ? 1600 LEU A CD2  1 
ATOM   2110 H  H    . LEU A 1 141 ? -9.93445  -4.40110  -1.92756  1.000 11.23996 ? 1600 LEU A H    1 
ATOM   2111 H  HA   . LEU A 1 141 ? -7.52593  -5.43265  -1.93188  1.000 11.88109 ? 1600 LEU A HA   1 
ATOM   2112 H  HB2  . LEU A 1 141 ? -8.64153  -3.16224  -3.06824  1.000 13.12545 ? 1600 LEU A HB2  1 
ATOM   2113 H  HB3  . LEU A 1 141 ? -7.05945  -3.31111  -3.08434  1.000 13.12545 ? 1600 LEU A HB3  1 
ATOM   2114 H  HG   . LEU A 1 141 ? -8.80994  -5.06111  -4.40778  1.000 17.69547 ? 1600 LEU A HG   1 
ATOM   2115 H  HD11 . LEU A 1 141 ? -8.12145  -4.20662  -6.39883  1.000 19.81151 ? 1600 LEU A HD11 1 
ATOM   2116 H  HD12 . LEU A 1 141 ? -8.92474  -3.14196  -5.53585  1.000 19.81151 ? 1600 LEU A HD12 1 
ATOM   2117 H  HD13 . LEU A 1 141 ? -7.34105  -3.05793  -5.62746  1.000 19.81151 ? 1600 LEU A HD13 1 
ATOM   2118 H  HD21 . LEU A 1 141 ? -6.67773  -5.80653  -5.39541  1.000 20.01048 ? 1600 LEU A HD21 1 
ATOM   2119 H  HD22 . LEU A 1 141 ? -5.97692  -5.02792  -4.20120  1.000 20.01048 ? 1600 LEU A HD22 1 
ATOM   2120 H  HD23 . LEU A 1 141 ? -6.92854  -6.26236  -3.89447  1.000 20.01048 ? 1600 LEU A HD23 1 
ATOM   2121 N  N    . MET A 1 142 ? -7.86557  -2.92245  0.00923   1.000 10.04333 ? 1601 MET A N    1 
ATOM   2122 C  CA   . MET A 1 142 ? -7.19920  -2.25742  1.12355   1.000 10.17492 ? 1601 MET A CA   1 
ATOM   2123 C  C    . MET A 1 142 ? -6.90322  -3.24964  2.24680   1.000 9.98806  ? 1601 MET A C    1 
ATOM   2124 O  O    . MET A 1 142 ? -5.79970  -3.25290  2.82302   1.000 10.58024 ? 1601 MET A O    1 
ATOM   2125 C  CB   . MET A 1 142 ? -8.06597  -1.10875  1.63095   1.000 10.91712 ? 1601 MET A CB   1 
ATOM   2126 C  CG   . MET A 1 142 ? -7.35399  -0.22973  2.63825   1.000 12.13832 ? 1601 MET A CG   1 
ATOM   2127 S  SD   . MET A 1 142 ? -5.97689  0.73552   1.95503   1.000 14.97550 ? 1601 MET A SD   1 
ATOM   2128 C  CE   . MET A 1 142 ? -4.57924  -0.04112  2.72099   1.000 16.40198 ? 1601 MET A CE   1 
ATOM   2129 H  H    . MET A 1 142 ? -8.66417  -2.65128  -0.15900  1.000 12.05479 ? 1601 MET A H    1 
ATOM   2130 H  HA   . MET A 1 142 ? -6.36166  -1.87940  0.81287   1.000 12.21271 ? 1601 MET A HA   1 
ATOM   2131 H  HB2  . MET A 1 142 ? -8.32418  -0.55337  0.87877   1.000 13.10334 ? 1601 MET A HB2  1 
ATOM   2132 H  HB3  . MET A 1 142 ? -8.85539  -1.47553  2.05896   1.000 13.10334 ? 1601 MET A HB3  1 
ATOM   2133 H  HG2  . MET A 1 142 ? -7.99468  0.39695   3.00930   1.000 14.56878 ? 1601 MET A HG2  1 
ATOM   2134 H  HG3  . MET A 1 142 ? -6.99551  -0.79325  3.34170   1.000 14.56878 ? 1601 MET A HG3  1 
ATOM   2135 H  HE1  . MET A 1 142 ? -3.76702  0.37313   2.38993   1.000 19.68518 ? 1601 MET A HE1  1 
ATOM   2136 H  HE2  . MET A 1 142 ? -4.64131  0.07415   3.68211   1.000 19.68518 ? 1601 MET A HE2  1 
ATOM   2137 H  HE3  . MET A 1 142 ? -4.58252  -0.98566  2.50023   1.000 19.68518 ? 1601 MET A HE3  1 
ATOM   2138 N  N    . VAL A 1 143 ? -7.86407  -4.11100  2.56401   1.000 9.71434  ? 1602 VAL A N    1 
ATOM   2139 C  CA   . VAL A 1 143 ? -7.64267  -5.10378  3.61197   1.000 10.18545 ? 1602 VAL A CA   1 
ATOM   2140 C  C    . VAL A 1 143 ? -6.50679  -6.04559  3.23392   1.000 10.02491 ? 1602 VAL A C    1 
ATOM   2141 O  O    . VAL A 1 143 ? -5.64814  -6.36676  4.06560   1.000 10.65393 ? 1602 VAL A O    1 
ATOM   2142 C  CB   . VAL A 1 143 ? -8.94980  -5.85969  3.89515   1.000 10.81974 ? 1602 VAL A CB   1 
ATOM   2143 C  CG1  . VAL A 1 143 ? -8.68835  -7.07791  4.72877   1.000 11.74880 ? 1602 VAL A CG1  1 
ATOM   2144 C  CG2  . VAL A 1 143 ? -9.93529  -4.91644  4.58890   1.000 11.56719 ? 1602 VAL A CG2  1 
ATOM   2145 H  H    . VAL A 1 143 ? -8.64033  -4.14267  2.19521   1.000 11.66001 ? 1602 VAL A H    1 
ATOM   2146 H  HA   . VAL A 1 143 ? -7.37578  -4.64647  4.42471   1.000 12.22534 ? 1602 VAL A HA   1 
ATOM   2147 H  HB   . VAL A 1 143 ? -9.34173  -6.16251  3.06112   1.000 12.98648 ? 1602 VAL A HB   1 
ATOM   2148 H  HG11 . VAL A 1 143 ? -9.51794  -7.35976  5.14498   1.000 14.10135 ? 1602 VAL A HG11 1 
ATOM   2149 H  HG12 . VAL A 1 143 ? -8.34812  -7.78431  4.15767   1.000 14.10135 ? 1602 VAL A HG12 1 
ATOM   2150 H  HG13 . VAL A 1 143 ? -8.03376  -6.85955  5.41048   1.000 14.10135 ? 1602 VAL A HG13 1 
ATOM   2151 H  HG21 . VAL A 1 143 ? -10.76256 -5.39349  4.75904   1.000 13.88343 ? 1602 VAL A HG21 1 
ATOM   2152 H  HG22 . VAL A 1 143 ? -9.54860  -4.61584  5.42616   1.000 13.88343 ? 1602 VAL A HG22 1 
ATOM   2153 H  HG23 . VAL A 1 143 ? -10.10478 -4.15607  4.01097   1.000 13.88343 ? 1602 VAL A HG23 1 
ATOM   2154 N  N    . ALA A 1 144 ? -6.45236  -6.43665  1.96617   1.000 9.97490  ? 1603 ALA A N    1 
ATOM   2155 C  CA   . ALA A 1 144 ? -5.36734  -7.29052  1.49429   1.000 10.60129 ? 1603 ALA A CA   1 
ATOM   2156 C  C    . ALA A 1 144 ? -4.01731  -6.60254  1.65541   1.000 10.73289 ? 1603 ALA A C    1 
ATOM   2157 O  O    . ALA A 1 144 ? -3.03697  -7.24192  2.05070   1.000 11.07240 ? 1603 ALA A O    1 
ATOM   2158 C  CB   . ALA A 1 144 ? -5.59845  -7.70106  0.04059   1.000 11.03555 ? 1603 ALA A CB   1 
ATOM   2159 H  H    . ALA A 1 144 ? -7.02605  -6.22421  1.36173   1.000 11.97268 ? 1603 ALA A H    1 
ATOM   2160 H  HA   . ALA A 1 144 ? -5.35817  -8.10125  2.02677   1.000 12.72435 ? 1603 ALA A HA   1 
ATOM   2161 H  HB1  . ALA A 1 144 ? -4.86110  -8.25991  -0.25079  1.000 13.24546 ? 1603 ALA A HB1  1 
ATOM   2162 H  HB2  . ALA A 1 144 ? -6.43138  -8.19452  -0.01961  1.000 13.24546 ? 1603 ALA A HB2  1 
ATOM   2163 H  HB3  . ALA A 1 144 ? -5.64615  -6.90327  -0.50910  1.000 13.24546 ? 1603 ALA A HB3  1 
ATOM   2164 N  N    . GLN A 1 145 ? -3.94160  -5.29128  1.37476   1.000 10.52497 ? 1604 GLN A N    1 
ATOM   2165 C  CA   . GLN A 1 145 ? -2.65576  -4.60693  1.52629   1.000 11.48824 ? 1604 GLN A CA   1 
ATOM   2166 C  C    . GLN A 1 145 ? -2.27729  -4.47243  2.99594   1.000 11.46192 ? 1604 GLN A C    1 
ATOM   2167 O  O    . GLN A 1 145 ? -1.09834  -4.59650  3.34763   1.000 12.00409 ? 1604 GLN A O    1 
ATOM   2168 C  CB   . GLN A 1 145 ? -2.65219  -3.22933  0.86189   1.000 13.13580 ? 1604 GLN A CB   1 
ATOM   2169 C  CG   . GLN A 1 145 ? -3.10264  -3.19330  -0.55404  1.000 14.64914 ? 1604 GLN A CG   1 
ATOM   2170 C  CD   . GLN A 1 145 ? -2.69921  -4.38030  -1.40570  1.000 15.81507 ? 1604 GLN A CD   1 
ATOM   2171 O  OE1  . GLN A 1 145 ? -1.51408  -4.72128  -1.51843  1.000 16.37040 ? 1604 GLN A OE1  1 
ATOM   2172 N  NE2  . GLN A 1 145 ? -3.71552  -5.11375  -1.89483  1.000 15.71243 ? 1604 GLN A NE2  1 
ATOM   2173 H  H    . GLN A 1 145 ? -4.59381  -4.79901  1.10666   1.000 12.63276 ? 1604 GLN A H    1 
ATOM   2174 H  HA   . GLN A 1 145 ? -1.99005  -5.14376  1.06852   1.000 13.78869 ? 1604 GLN A HA   1 
ATOM   2175 H  HB2  . GLN A 1 145 ? -3.24200  -2.64724  1.36607   1.000 15.76576 ? 1604 GLN A HB2  1 
ATOM   2176 H  HB3  . GLN A 1 145 ? -1.74621  -2.88351  0.88420   1.000 15.76576 ? 1604 GLN A HB3  1 
ATOM   2177 H  HG2  . GLN A 1 145 ? -4.07159  -3.14933  -0.56399  1.000 17.58177 ? 1604 GLN A HG2  1 
ATOM   2178 H  HG3  . GLN A 1 145 ? -2.73028  -2.40095  -0.97166  1.000 17.58177 ? 1604 GLN A HG3  1 
ATOM   2179 H  HE21 . GLN A 1 145 ? -4.52805  -4.89551  -1.71659  1.000 18.85771 ? 1604 GLN A HE21 1 
ATOM   2180 H  HE22 . GLN A 1 145 ? -3.55264  -5.80083  -2.38574  1.000 18.85771 ? 1604 GLN A HE22 1 
ATOM   2181 N  N    . LEU A 1 146 ? -3.25457  -4.18808  3.87212   1.000 12.44098 ? 1605 LEU A N    1 
ATOM   2182 C  CA   . LEU A 1 146 ? -2.97693  -4.03157  5.29302   1.000 12.82787 ? 1605 LEU A CA   1 
ATOM   2183 C  C    . LEU A 1 146 ? -2.43370  -5.32097  5.87754   1.000 13.53322 ? 1605 LEU A C    1 
ATOM   2184 O  O    . LEU A 1 146 ? -1.60034  -5.30202  6.79482   1.000 15.15710 ? 1605 LEU A O    1 
ATOM   2185 C  CB   . LEU A 1 146 ? -4.25022  -3.60712  6.04616   1.000 13.32530 ? 1605 LEU A CB   1 
ATOM   2186 C  CG   . LEU A 1 146 ? -4.73695  -2.17476  5.82228   1.000 14.63862 ? 1605 LEU A CG   1 
ATOM   2187 C  CD1  . LEU A 1 146 ? -6.13816  -1.96789  6.37301   1.000 14.97813 ? 1605 LEU A CD1  1 
ATOM   2188 C  CD2  . LEU A 1 146 ? -3.76006  -1.17978  6.44482   1.000 15.04130 ? 1605 LEU A CD2  1 
ATOM   2189 H  H    . LEU A 1 146 ? -4.08204  -4.08245  3.66300   1.000 14.93198 ? 1605 LEU A H    1 
ATOM   2190 H  HA   . LEU A 1 146 ? -2.31773  -3.32977  5.41063   1.000 15.39625 ? 1605 LEU A HA   1 
ATOM   2191 H  HB2  . LEU A 1 146 ? -4.97007  -4.19750  5.77383   1.000 15.99316 ? 1605 LEU A HB2  1 
ATOM   2192 H  HB3  . LEU A 1 146 ? -4.08260  -3.70481  6.99656   1.000 15.99316 ? 1605 LEU A HB3  1 
ATOM   2193 H  HG   . LEU A 1 146 ? -4.77775  -2.00990  4.86726   1.000 17.56914 ? 1605 LEU A HG   1 
ATOM   2194 H  HD11 . LEU A 1 146 ? -6.40580  -1.04849  6.21815   1.000 17.97655 ? 1605 LEU A HD11 1 
ATOM   2195 H  HD12 . LEU A 1 146 ? -6.74792  -2.57075  5.91951   1.000 17.97655 ? 1605 LEU A HD12 1 
ATOM   2196 H  HD13 . LEU A 1 146 ? -6.13431  -2.15546  7.32469   1.000 17.97655 ? 1605 LEU A HD13 1 
ATOM   2197 H  HD21 . LEU A 1 146 ? -4.11126  -0.28217  6.33594   1.000 18.05235 ? 1605 LEU A HD21 1 
ATOM   2198 H  HD22 . LEU A 1 146 ? -3.65976  -1.38362  7.38784   1.000 18.05235 ? 1605 LEU A HD22 1 
ATOM   2199 H  HD23 . LEU A 1 146 ? -2.90308  -1.25626  5.99690   1.000 18.05235 ? 1605 LEU A HD23 1 
ATOM   2200 N  N    . THR A 1 147 ? -2.88001  -6.46016  5.34734   1.000 14.14382 ? 1606 THR A N    1 
ATOM   2201 C  CA   . THR A 1 147 ? -2.45667  -7.77738  5.79701   1.000 15.13341 ? 1606 THR A CA   1 
ATOM   2202 C  C    . THR A 1 147 ? -1.36469  -8.38692  4.90888   1.000 15.92298 ? 1606 THR A C    1 
ATOM   2203 O  O    . THR A 1 147 ? -0.96418  -9.53253  5.14792   1.000 17.57318 ? 1606 THR A O    1 
ATOM   2204 C  CB   . THR A 1 147 ? -3.68634  -8.68790  5.93935   1.000 14.80180 ? 1606 THR A CB   1 
ATOM   2205 O  OG1  . THR A 1 147 ? -4.33609  -8.87583  4.67951   1.000 14.35700 ? 1606 THR A OG1  1 
ATOM   2206 C  CG2  . THR A 1 147 ? -4.68974  -8.08635  6.89999   1.000 15.41766 ? 1606 THR A CG2  1 
ATOM   2207 H  H    . THR A 1 147 ? -3.44882  -6.49263  4.70313   1.000 16.97538 ? 1606 THR A H    1 
ATOM   2208 H  HA   . THR A 1 147 ? -2.06308  -7.71994  6.68171   1.000 18.16289 ? 1606 THR A HA   1 
ATOM   2209 H  HB   . THR A 1 147 ? -3.38506  -9.54580  6.27719   1.000 17.76495 ? 1606 THR A HB   1 
ATOM   2210 H  HG1  . THR A 1 147 ? -4.59603  -8.13648  4.37719   1.000 17.23120 ? 1606 THR A HG1  1 
ATOM   2211 H  HG21 . THR A 1 147 ? -5.41476  -8.71135  7.05685   1.000 18.50399 ? 1606 THR A HG21 1 
ATOM   2212 H  HG22 . THR A 1 147 ? -4.25961  -7.88450  7.74565   1.000 18.50399 ? 1606 THR A HG22 1 
ATOM   2213 H  HG23 . THR A 1 147 ? -5.05456  -7.26768  6.52906   1.000 18.50399 ? 1606 THR A HG23 1 
ATOM   2214 N  N    . GLN A 1 148 ? -0.88175  -7.61950  3.91278   1.000 15.64926 ? 1607 GLN A N    1 
ATOM   2215 C  CA   A GLN A 1 148 ? 0.27384   -7.99405  3.10453   0.495 14.63335 ? 1607 GLN A CA   1 
ATOM   2216 C  CA   B GLN A 1 148 ? 0.23102   -7.93617  3.00208   0.505 15.29396 ? 1607 GLN A CA   1 
ATOM   2217 C  C    . GLN A 1 148 ? 0.09363   -9.31559  2.35021   1.000 14.28595 ? 1607 GLN A C    1 
ATOM   2218 O  O    . GLN A 1 148 ? 0.99294   -10.16782 2.35216   1.000 15.84929 ? 1607 GLN A O    1 
ATOM   2219 C  CB   A GLN A 1 148 ? 1.52471   -8.06877  3.99223   0.495 14.98866 ? 1607 GLN A CB   1 
ATOM   2220 C  CB   B GLN A 1 148 ? 1.60350   -7.68715  3.63503   0.505 16.99943 ? 1607 GLN A CB   1 
ATOM   2221 C  CG   A GLN A 1 148 ? 1.87047   -6.78075  4.72446   0.495 15.84666 ? 1607 GLN A CG   1 
ATOM   2222 C  CG   B GLN A 1 148 ? 1.95510   -6.18802  3.69244   0.505 18.11008 ? 1607 GLN A CG   1 
ATOM   2223 C  CD   A GLN A 1 148 ? 3.09127   -6.92956  5.62570   0.495 17.06522 ? 1607 GLN A CD   1 
ATOM   2224 C  CD   B GLN A 1 148 ? 2.19810   -5.55492  2.31072   0.505 18.39433 ? 1607 GLN A CD   1 
ATOM   2225 O  OE1  A GLN A 1 148 ? 2.98168   -7.00655  6.84918   0.495 18.55751 ? 1607 GLN A OE1  1 
ATOM   2226 O  OE1  B GLN A 1 148 ? 3.16059   -5.91686  1.62765   0.505 20.47089 ? 1607 GLN A OE1  1 
ATOM   2227 N  NE2  A GLN A 1 148 ? 4.25527   -7.03466  5.00993   0.495 17.53633 ? 1607 GLN A NE2  1 
ATOM   2228 N  NE2  B GLN A 1 148 ? 1.32875   -4.59408  1.90102   0.505 16.48358 ? 1607 GLN A NE2  1 
ATOM   2229 H  H    A GLN A 1 148 ? -1.22053  -6.86167  3.68800   0.495 18.78191 ? 1607 GLN A H    1 
ATOM   2230 H  H    B GLN A 1 148 ? -1.21171  -6.84624  3.73169   0.505 18.78191 ? 1607 GLN A H    1 
ATOM   2231 H  HA   A GLN A 1 148 ? 0.37793   -7.30998  2.42474   0.495 17.56282 ? 1607 GLN A HA   1 
ATOM   2232 H  HA   B GLN A 1 148 ? 0.16876   -7.30793  2.26564   0.505 18.35555 ? 1607 GLN A HA   1 
ATOM   2233 H  HB2  A GLN A 1 148 ? 1.38505   -8.75596  4.66242   0.495 17.98919 ? 1607 GLN A HB2  1 
ATOM   2234 H  HB2  B GLN A 1 148 ? 1.60290   -8.03285  4.54133   0.505 20.40211 ? 1607 GLN A HB2  1 
ATOM   2235 H  HB3  A GLN A 1 148 ? 2.28398   -8.29902  3.43419   0.495 17.98919 ? 1607 GLN A HB3  1 
ATOM   2236 H  HB3  B GLN A 1 148 ? 2.28257   -8.13738  3.10867   0.505 20.40211 ? 1607 GLN A HB3  1 
ATOM   2237 H  HG2  A GLN A 1 148 ? 2.06011   -6.08726  4.07331   0.495 19.01879 ? 1607 GLN A HG2  1 
ATOM   2238 H  HG2  B GLN A 1 148 ? 1.22167   -5.71108  4.11138   0.505 21.73490 ? 1607 GLN A HG2  1 
ATOM   2239 H  HG3  A GLN A 1 148 ? 1.11808   -6.51926  5.27803   0.495 19.01879 ? 1607 GLN A HG3  1 
ATOM   2240 H  HG3  B GLN A 1 148 ? 2.76465   -6.07694  4.21511   0.505 21.73490 ? 1607 GLN A HG3  1 
ATOM   2241 H  HE21 A GLN A 1 148 ? 4.29041   -7.01688  4.15083   0.495 21.04640 ? 1607 GLN A HE21 1 
ATOM   2242 H  HE21 B GLN A 1 148 ? 0.67407   -4.36201  2.40811   0.505 19.78309 ? 1607 GLN A HE21 1 
ATOM   2243 H  HE22 A GLN A 1 148 ? 4.97790   -7.12087  5.46815   0.495 21.04640 ? 1607 GLN A HE22 1 
ATOM   2244 H  HE22 B GLN A 1 148 ? 1.43329   -4.21810  1.13466   0.505 19.78309 ? 1607 GLN A HE22 1 
ATOM   2245 N  N    . ARG A 1 149 ? -1.04966  -9.49454  1.70678   1.000 12.15411 ? 1608 ARG A N    1 
ATOM   2246 C  CA   . ARG A 1 149 ? -1.26029  -10.70005 0.91540   1.000 10.83027 ? 1608 ARG A CA   1 
ATOM   2247 C  C    . ARG A 1 149 ? -2.11418  -10.41721 -0.31441  1.000 10.67235 ? 1608 ARG A C    1 
ATOM   2248 O  O    . ARG A 1 149 ? -2.57148  -9.29308  -0.54540  1.000 10.91185 ? 1608 ARG A O    1 
ATOM   2249 C  CB   . ARG A 1 149 ? -1.81372  -11.82573 1.78746   1.000 11.22768 ? 1608 ARG A CB   1 
ATOM   2250 C  CG   . ARG A 1 149 ? -3.22261  -11.59565 2.30317   1.000 11.53561 ? 1608 ARG A CG   1 
ATOM   2251 C  CD   . ARG A 1 149 ? -3.92139  -12.91246 2.54274   1.000 11.93566 ? 1608 ARG A CD   1 
ATOM   2252 N  NE   . ARG A 1 149 ? -4.19931  -13.53990 1.25830   1.000 11.84091 ? 1608 ARG A NE   1 
ATOM   2253 C  CZ   . ARG A 1 149 ? -4.31161  -14.84321 1.04594   1.000 12.14358 ? 1608 ARG A CZ   1 
ATOM   2254 N  NH1  . ARG A 1 149 ? -4.24444  -15.71466 2.04507   1.000 12.57521 ? 1608 ARG A NH1  1 
ATOM   2255 N  NH2  . ARG A 1 149 ? -4.48917  -15.27891 -0.19895  1.000 12.25149 ? 1608 ARG A NH2  1 
ATOM   2256 H  H    . ARG A 1 149 ? -1.70902  -8.94244  1.71174   1.000 14.58773 ? 1608 ARG A H    1 
ATOM   2257 H  HA   . ARG A 1 149 ? -0.40111  -10.97870 0.56176   1.000 12.99912 ? 1608 ARG A HA   1 
ATOM   2258 H  HB2  . ARG A 1 149 ? -1.82380  -12.64319 1.26539   1.000 13.47601 ? 1608 ARG A HB2  1 
ATOM   2259 H  HB3  . ARG A 1 149 ? -1.23435  -11.93144 2.55821   1.000 13.47601 ? 1608 ARG A HB3  1 
ATOM   2260 H  HG2  . ARG A 1 149 ? -3.18629  -11.10843 3.14114   1.000 13.84553 ? 1608 ARG A HG2  1 
ATOM   2261 H  HG3  . ARG A 1 149 ? -3.73007  -11.09152 1.64801   1.000 13.84553 ? 1608 ARG A HG3  1 
ATOM   2262 H  HD2  . ARG A 1 149 ? -3.35171  -13.49930 3.06426   1.000 14.32559 ? 1608 ARG A HD2  1 
ATOM   2263 H  HD3  . ARG A 1 149 ? -4.75876  -12.76271 3.00889   1.000 14.32559 ? 1608 ARG A HD3  1 
ATOM   2264 H  HE   . ARG A 1 149 ? -4.29901  -13.02063 0.58005   1.000 14.21189 ? 1608 ARG A HE   1 
ATOM   2265 H  HH11 . ARG A 1 149 ? -4.12577  -15.43722 2.85039   1.000 15.09305 ? 1608 ARG A HH11 1 
ATOM   2266 H  HH12 . ARG A 1 149 ? -4.31959  -16.55667 1.88703   1.000 15.09305 ? 1608 ARG A HH12 1 
ATOM   2267 H  HH21 . ARG A 1 149 ? -4.52930  -14.71768 -0.84934  1.000 14.70458 ? 1608 ARG A HH21 1 
ATOM   2268 H  HH22 . ARG A 1 149 ? -4.56379  -16.12170 -0.35302  1.000 14.70458 ? 1608 ARG A HH22 1 
ATOM   2269 N  N    . SER A 1 150 ? -2.34254  -11.46108 -1.09272  1.000 10.48812 ? 1609 SER A N    1 
ATOM   2270 C  CA   . SER A 1 150 ? -3.08786  -11.39981 -2.33440  1.000 10.10123 ? 1609 SER A CA   1 
ATOM   2271 C  C    . SER A 1 150 ? -4.58504  -11.57494 -2.10622  1.000 9.29587  ? 1609 SER A C    1 
ATOM   2272 O  O    . SER A 1 150 ? -5.03484  -12.02786 -1.05378  1.000 10.37231 ? 1609 SER A O    1 
ATOM   2273 C  CB   . SER A 1 150 ? -2.57875  -12.48004 -3.28959  1.000 11.05135 ? 1609 SER A CB   1 
ATOM   2274 O  OG   . SER A 1 150 ? -2.89387  -13.76968 -2.80945  1.000 12.98842 ? 1609 SER A OG   1 
ATOM   2275 H  H    . SER A 1 150 ? -2.06222  -12.25425 -0.91407  1.000 12.58854 ? 1609 SER A H    1 
ATOM   2276 H  HA   . SER A 1 150 ? -2.96108  -10.52654 -2.73717  1.000 12.12428 ? 1609 SER A HA   1 
ATOM   2277 H  HB2  . SER A 1 150 ? -2.99576  -12.35600 -4.15656  1.000 13.26441 ? 1609 SER A HB2  1 
ATOM   2278 H  HB3  . SER A 1 150 ? -1.61540  -12.40060 -3.37041  1.000 13.26441 ? 1609 SER A HB3  1 
ATOM   2279 H  HG   . SER A 1 150 ? -2.44123  -14.34707 -3.21852  1.000 15.58890 ? 1609 SER A HG   1 
ATOM   2280 N  N    . VAL A 1 151 ? -5.34241  -11.20917 -3.12939  1.000 9.60380  ? 1610 VAL A N    1 
ATOM   2281 C  CA   . VAL A 1 151 ? -6.78006  -11.48152 -3.16564  1.000 9.88805  ? 1610 VAL A CA   1 
ATOM   2282 C  C    . VAL A 1 151 ? -7.18506  -11.65964 -4.61777  1.000 9.95911  ? 1610 VAL A C    1 
ATOM   2283 O  O    . VAL A 1 151 ? -6.61134  -11.05989 -5.53088  1.000 10.01964 ? 1610 VAL A O    1 
ATOM   2284 C  CB   . VAL A 1 151 ? -7.60051  -10.38068 -2.45553  1.000 10.45391 ? 1610 VAL A CB   1 
ATOM   2285 C  CG1  . VAL A 1 151 ? -7.45535  -9.05047  -3.16147  1.000 10.86974 ? 1610 VAL A CG1  1 
ATOM   2286 C  CG2  . VAL A 1 151 ? -9.08172  -10.77929 -2.34410  1.000 11.35401 ? 1610 VAL A CG2  1 
ATOM   2287 H  H    . VAL A 1 151 ? -5.04827  -10.79711 -3.82458  1.000 11.52736 ? 1610 VAL A H    1 
ATOM   2288 H  HA   . VAL A 1 151 ? -6.96511  -12.31265 -2.70101  1.000 11.86845 ? 1610 VAL A HA   1 
ATOM   2289 H  HB   . VAL A 1 151 ? -7.25125  -10.27889 -1.55633  1.000 12.54748 ? 1610 VAL A HB   1 
ATOM   2290 H  HG11 . VAL A 1 151 ? -7.47074  -8.33952  -2.50177  1.000 13.04649 ? 1610 VAL A HG11 1 
ATOM   2291 H  HG12 . VAL A 1 151 ? -6.61259  -9.03805  -3.64157  1.000 13.04649 ? 1610 VAL A HG12 1 
ATOM   2292 H  HG13 . VAL A 1 151 ? -8.19184  -8.94086  -3.78314  1.000 13.04649 ? 1610 VAL A HG13 1 
ATOM   2293 H  HG21 . VAL A 1 151 ? -9.54705  -10.11861 -1.80757  1.000 13.62761 ? 1610 VAL A HG21 1 
ATOM   2294 H  HG22 . VAL A 1 151 ? -9.46716  -10.81409 -3.23355  1.000 13.62761 ? 1610 VAL A HG22 1 
ATOM   2295 H  HG23 . VAL A 1 151 ? -9.14340  -11.65072 -1.92254  1.000 13.62761 ? 1610 VAL A HG23 1 
ATOM   2296 N  N    . HIS A 1 152 ? -8.18824  -12.51346 -4.83296  1.000 9.59591  ? 1611 HIS A N    1 
ATOM   2297 C  CA   . HIS A 1 152 ? -8.79152  -12.74228 -6.13492  1.000 9.24060  ? 1611 HIS A CA   1 
ATOM   2298 C  C    . HIS A 1 152 ? -10.23812 -12.24557 -6.12510  1.000 8.70896  ? 1611 HIS A C    1 
ATOM   2299 O  O    . HIS A 1 152 ? -11.01193 -12.60170 -5.22913  1.000 9.97227  ? 1611 HIS A O    1 
ATOM   2300 C  CB   . HIS A 1 152 ? -8.75049  -14.23171 -6.43232  1.000 9.27482  ? 1611 HIS A CB   1 
ATOM   2301 C  CG   . HIS A 1 152 ? -9.36607  -14.59794 -7.72373  1.000 9.44852  ? 1611 HIS A CG   1 
ATOM   2302 N  ND1  . HIS A 1 152 ? -8.69027  -14.54124 -8.92456  1.000 9.74329  ? 1611 HIS A ND1  1 
ATOM   2303 C  CD2  . HIS A 1 152 ? -10.60124 -15.08147 -8.00095  1.000 9.26166  ? 1611 HIS A CD2  1 
ATOM   2304 C  CE1  . HIS A 1 152 ? -9.48763  -14.96569 -9.88609  1.000 9.83014  ? 1611 HIS A CE1  1 
ATOM   2305 N  NE2  . HIS A 1 152 ? -10.65951 -15.29750 -9.34711  1.000 9.31956  ? 1611 HIS A NE2  1 
ATOM   2306 H  H    . HIS A 1 152 ? -8.54632  -12.98778 -4.21135  1.000 11.51789 ? 1611 HIS A H    1 
ATOM   2307 H  HA   . HIS A 1 152 ? -8.31984  -12.25212 -6.82641  1.000 11.09152 ? 1611 HIS A HA   1 
ATOM   2308 H  HB2  . HIS A 1 152 ? -7.82460  -14.52011 -6.45338  1.000 11.13258 ? 1611 HIS A HB2  1 
ATOM   2309 H  HB3  . HIS A 1 152 ? -9.22886  -14.70279 -5.73221  1.000 11.13258 ? 1611 HIS A HB3  1 
ATOM   2310 H  HD2  . HIS A 1 152 ? -11.28275 -15.23719 -7.38760  1.000 11.11679 ? 1611 HIS A HD2  1 
ATOM   2311 H  HE1  . HIS A 1 152 ? -9.26843  -15.02347 -10.78803 1.000 11.79897 ? 1611 HIS A HE1  1 
ATOM   2312 H  HE2  . HIS A 1 152 ? -11.34095 -15.59844 -9.77684  1.000 11.18627 ? 1611 HIS A HE2  1 
ATOM   2313 N  N    . ILE A 1 153 ? -10.58341 -11.40962 -7.09965  1.000 8.43261  ? 1612 ILE A N    1 
ATOM   2314 C  CA   . ILE A 1 153 ? -11.90957 -10.81011 -7.18140  1.000 8.65369  ? 1612 ILE A CA   1 
ATOM   2315 C  C    . ILE A 1 153 ? -12.78055 -11.65200 -8.10416  1.000 8.34313  ? 1612 ILE A C    1 
ATOM   2316 O  O    . ILE A 1 153 ? -12.48689 -11.82907 -9.28586  1.000 9.26429  ? 1612 ILE A O    1 
ATOM   2317 C  CB   . ILE A 1 153 ? -11.84267 -9.36521  -7.69575  1.000 8.61158  ? 1612 ILE A CB   1 
ATOM   2318 C  CG1  . ILE A 1 153 ? -10.84635 -8.54874  -6.87800  1.000 9.65907  ? 1612 ILE A CG1  1 
ATOM   2319 C  CG2  . ILE A 1 153 ? -13.26118 -8.73808  -7.68055  1.000 8.89845  ? 1612 ILE A CG2  1 
ATOM   2320 C  CD1  . ILE A 1 153 ? -11.11510 -8.45524  -5.42166  1.000 11.09345 ? 1612 ILE A CD1  1 
ATOM   2321 H  H    . ILE A 1 153 ? -10.05697 -11.17045 -7.73625  1.000 10.12193 ? 1612 ILE A H    1 
ATOM   2322 H  HA   . ILE A 1 153 ? -12.30043 -10.81391 -6.29364  1.000 10.38722 ? 1612 ILE A HA   1 
ATOM   2323 H  HB   . ILE A 1 153 ? -11.52396 -9.36627  -8.61190  1.000 10.33669 ? 1612 ILE A HB   1 
ATOM   2324 H  HG12 . ILE A 1 153 ? -9.96942  -8.95026  -6.98136  1.000 11.59368 ? 1612 ILE A HG12 1 
ATOM   2325 H  HG13 . ILE A 1 153 ? -10.83975 -7.64329  -7.22588  1.000 11.59368 ? 1612 ILE A HG13 1 
ATOM   2326 H  HG21 . ILE A 1 153 ? -13.19011 -7.79146  -7.87994  1.000 10.68094 ? 1612 ILE A HG21 1 
ATOM   2327 H  HG22 . ILE A 1 153 ? -13.80780 -9.17718  -8.35084  1.000 10.68094 ? 1612 ILE A HG22 1 
ATOM   2328 H  HG23 . ILE A 1 153 ? -13.65208 -8.86253  -6.80156  1.000 10.68094 ? 1612 ILE A HG23 1 
ATOM   2329 H  HD11 . ILE A 1 153 ? -10.46278 -7.86184  -5.01761  1.000 13.31494 ? 1612 ILE A HD11 1 
ATOM   2330 H  HD12 . ILE A 1 153 ? -12.00937 -8.10428  -5.28744  1.000 13.31494 ? 1612 ILE A HD12 1 
ATOM   2331 H  HD13 . ILE A 1 153 ? -11.04474 -9.33991  -5.03011  1.000 13.31494 ? 1612 ILE A HD13 1 
ATOM   2332 N  N    . CYS A 1 154 ? -13.90391 -12.12678 -7.56715  1.000 8.75896  ? 1613 CYS A N    1 
ATOM   2333 C  CA   . CYS A 1 154 ? -14.84818 -12.90745 -8.34843  1.000 8.78265  ? 1613 CYS A CA   1 
ATOM   2334 C  C    . CYS A 1 154 ? -15.61006 -12.00849 -9.32027  1.000 8.68790  ? 1613 CYS A C    1 
ATOM   2335 O  O    . CYS A 1 154 ? -15.75817 -10.79747 -9.10446  1.000 9.09321  ? 1613 CYS A O    1 
ATOM   2336 C  CB   . CYS A 1 154 ? -15.83000 -13.59868 -7.40612  1.000 9.31166  ? 1613 CYS A CB   1 
ATOM   2337 S  SG   . CYS A 1 154 ? -15.06246 -14.86984 -6.36551  1.000 10.31968 ? 1613 CYS A SG   1 
ATOM   2338 H  H    . CYS A 1 154 ? -14.13998 -12.00815 -6.74874  1.000 10.51355 ? 1613 CYS A H    1 
ATOM   2339 H  HA   . CYS A 1 154 ? -14.37877 -13.57953 -8.86694  1.000 10.54198 ? 1613 CYS A HA   1 
ATOM   2340 H  HB2  . CYS A 1 154 ? -16.22274 -12.93258 -6.82049  1.000 11.17679 ? 1613 CYS A HB2  1 
ATOM   2341 H  HB3  . CYS A 1 154 ? -16.52246 -14.02552 -7.93452  1.000 11.17679 ? 1613 CYS A HB3  1 
ATOM   2342 N  N    . HIS A 1 155 ? -16.14101 -12.63414 -10.37010 1.000 8.66948  ? 1614 HIS A N    1 
ATOM   2343 C  CA   . HIS A 1 155 ? -17.03656 -12.05940 -11.37680 1.000 8.92214  ? 1614 HIS A CA   1 
ATOM   2344 C  C    . HIS A 1 155 ? -17.01665 -10.53768 -11.43985 1.000 8.62211  ? 1614 HIS A C    1 
ATOM   2345 O  O    . HIS A 1 155 ? -17.92758 -9.85087  -10.96375 1.000 9.64591  ? 1614 HIS A O    1 
ATOM   2346 C  CB   . HIS A 1 155 ? -18.48524 -12.57081 -11.17513 1.000 8.62211  ? 1614 HIS A CB   1 
ATOM   2347 C  CG   . HIS A 1 155 ? -18.90025 -12.64373 -9.74640  1.000 8.09836  ? 1614 HIS A CG   1 
ATOM   2348 N  ND1  . HIS A 1 155 ? -18.74122 -11.59053 -8.87651  1.000 8.63000  ? 1614 HIS A ND1  1 
ATOM   2349 C  CD2  . HIS A 1 155 ? -19.46816 -13.63868 -9.02148  1.000 9.01426  ? 1614 HIS A CD2  1 
ATOM   2350 C  CE1  . HIS A 1 155 ? -19.17635 -11.92442 -7.68699  1.000 9.46168  ? 1614 HIS A CE1  1 
ATOM   2351 N  NE2  . HIS A 1 155 ? -19.61340 -13.16970 -7.74927  1.000 9.55643  ? 1614 HIS A NE2  1 
ATOM   2352 H  H    . HIS A 1 155 ? -15.98591 -13.46327 -10.53773 1.000 10.40617 ? 1614 HIS A H    1 
ATOM   2353 H  HA   . HIS A 1 155 ? -16.70703 -12.35982 -12.23823 1.000 10.70937 ? 1614 HIS A HA   1 
ATOM   2354 H  HB2  . HIS A 1 155 ? -19.09491 -11.96934 -11.63057 1.000 10.34933 ? 1614 HIS A HB2  1 
ATOM   2355 H  HB3  . HIS A 1 155 ? -18.55666 -13.46242 -11.55043 1.000 10.34933 ? 1614 HIS A HB3  1 
ATOM   2356 H  HD1  . HIS A 1 155 ? -18.40581 -10.82600 -9.08292  1.000 10.35880 ? 1614 HIS A HD1  1 
ATOM   2357 H  HD2  . HIS A 1 155 ? -19.71214 -14.48048 -9.33251  1.000 10.81991 ? 1614 HIS A HD2  1 
ATOM   2358 H  HE1  . HIS A 1 155 ? -19.17745 -11.38110 -6.93220  1.000 11.35681 ? 1614 HIS A HE1  1 
ATOM   2359 N  N    . VAL A 1 156 ? -15.98024 -10.01424 -12.07478 1.000 8.50630  ? 1615 VAL A N    1 
ATOM   2360 C  CA   . VAL A 1 156 ? -15.90017 -8.57820  -12.31573 1.000 8.50894  ? 1615 VAL A CA   1 
ATOM   2361 C  C    . VAL A 1 156 ? -16.88023 -8.23595  -13.42988 1.000 8.56684  ? 1615 VAL A C    1 
ATOM   2362 O  O    . VAL A 1 156 ? -16.91121 -8.89484  -14.48052 1.000 9.83278  ? 1615 VAL A O    1 
ATOM   2363 C  CB   . VAL A 1 156 ? -14.46190 -8.18493  -12.67336 1.000 9.75119  ? 1615 VAL A CB   1 
ATOM   2364 C  CG1  . VAL A 1 156 ? -14.40959 -6.73502  -13.13202 1.000 10.36179 ? 1615 VAL A CG1  1 
ATOM   2365 C  CG2  . VAL A 1 156 ? -13.56563 -8.42394  -11.48185 1.000 9.53011  ? 1615 VAL A CG2  1 
ATOM   2366 H  H    . VAL A 1 156 ? -15.31192 -10.46392 -12.37598 1.000 10.21036 ? 1615 VAL A H    1 
ATOM   2367 H  HA   . VAL A 1 156 ? -16.14907 -8.08307  -11.51962 1.000 10.21352 ? 1615 VAL A HA   1 
ATOM   2368 H  HB   . VAL A 1 156 ? -14.14009 -8.73039  -13.40808 1.000 11.70422 ? 1615 VAL A HB   1 
ATOM   2369 H  HG11 . VAL A 1 156 ? -13.48761 -6.43376  -13.12221 1.000 12.43694 ? 1615 VAL A HG11 1 
ATOM   2370 H  HG12 . VAL A 1 156 ? -14.76755 -6.67525  -14.03157 1.000 12.43694 ? 1615 VAL A HG12 1 
ATOM   2371 H  HG13 . VAL A 1 156 ? -14.94103 -6.19331  -12.52786 1.000 12.43694 ? 1615 VAL A HG13 1 
ATOM   2372 H  HG21 . VAL A 1 156 ? -12.66452 -8.14086  -11.70269 1.000 11.43893 ? 1615 VAL A HG21 1 
ATOM   2373 H  HG22 . VAL A 1 156 ? -13.89819 -7.91115  -10.72862 1.000 11.43893 ? 1615 VAL A HG22 1 
ATOM   2374 H  HG23 . VAL A 1 156 ? -13.57185 -9.36975  -11.26668 1.000 11.43893 ? 1615 VAL A HG23 1 
ATOM   2375 N  N    . ALA A 1 157 ? -17.73277 -7.23751  -13.19227 1.000 9.50905  ? 1616 ALA A N    1 
ATOM   2376 C  CA   . ALA A 1 157 ? -18.91350 -7.04505  -14.01867 1.000 9.90647  ? 1616 ALA A CA   1 
ATOM   2377 C  C    . ALA A 1 157 ? -19.06174 -5.63616  -14.54972 1.000 10.30652 ? 1616 ALA A C    1 
ATOM   2378 O  O    . ALA A 1 157 ? -19.97864 -5.39203  -15.33909 1.000 11.36980 ? 1616 ALA A O    1 
ATOM   2379 C  CB   . ALA A 1 157 ? -20.17218 -7.36838  -13.20544 1.000 10.09860 ? 1616 ALA A CB   1 
ATOM   2380 H  H    . ALA A 1 157 ? -17.64514 -6.66244  -12.55886 1.000 11.41366 ? 1616 ALA A H    1 
ATOM   2381 H  HA   . ALA A 1 157 ? -18.86334 -7.65023  -14.77507 1.000 11.89056 ? 1616 ALA A HA   1 
ATOM   2382 H  HB1  . ALA A 1 157 ? -20.95357 -7.22117  -13.76101 1.000 12.12112 ? 1616 ALA A HB1  1 
ATOM   2383 H  HB2  . ALA A 1 157 ? -20.13656 -8.29590  -12.92378 1.000 12.12112 ? 1616 ALA A HB2  1 
ATOM   2384 H  HB3  . ALA A 1 157 ? -20.20426 -6.78789  -12.42898 1.000 12.12112 ? 1616 ALA A HB3  1 
ATOM   2385 N  N    . ARG A 1 158 ? -18.20080 -4.71236  -14.14922 1.000 9.85647  ? 1617 ARG A N    1 
ATOM   2386 C  CA   . ARG A 1 158 ? -18.39360 -3.30732  -14.44176 1.000 10.25915 ? 1617 ARG A CA   1 
ATOM   2387 C  C    . ARG A 1 158 ? -17.10420 -2.66724  -14.91094 1.000 10.13545 ? 1617 ARG A C    1 
ATOM   2388 O  O    . ARG A 1 158 ? -16.01384 -3.03596  -14.46028 1.000 10.43022 ? 1617 ARG A O    1 
ATOM   2389 C  CB   . ARG A 1 158 ? -18.78750 -2.54615  -13.17153 1.000 11.23558 ? 1617 ARG A CB   1 
ATOM   2390 C  CG   . ARG A 1 158 ? -20.15767 -2.92186  -12.60324 1.000 12.44099 ? 1617 ARG A CG   1 
ATOM   2391 C  CD   . ARG A 1 158 ? -20.37896 -2.33443  -11.24282 1.000 13.64639 ? 1617 ARG A CD   1 
ATOM   2392 N  NE   . ARG A 1 158 ? -21.74324 -2.54223  -10.76843 1.000 14.29647 ? 1617 ARG A NE   1 
ATOM   2393 C  CZ   . ARG A 1 158 ? -22.16456 -3.58968  -10.07624 1.000 14.32016 ? 1617 ARG A CZ   1 
ATOM   2394 N  NH1  . ARG A 1 158 ? -21.33101 -4.53942  -9.66479  1.000 13.84642 ? 1617 ARG A NH1  1 
ATOM   2395 N  NH2  . ARG A 1 158 ? -23.45700 -3.69476  -9.79652  1.000 15.31501 ? 1617 ARG A NH2  1 
ATOM   2396 H  H    . ARG A 1 158 ? -17.48721 -4.88069  -13.69973 1.000 11.83056 ? 1617 ARG A H    1 
ATOM   2397 H  HA   . ARG A 1 158 ? -19.06755 -3.23796  -15.13593 1.000 12.31377 ? 1617 ARG A HA   1 
ATOM   2398 H  HB2  . ARG A 1 158 ? -18.12634 -2.72781  -12.48541 1.000 13.48549 ? 1617 ARG A HB2  1 
ATOM   2399 H  HB3  . ARG A 1 158 ? -18.80446 -1.59746  -13.37304 1.000 13.48549 ? 1617 ARG A HB3  1 
ATOM   2400 H  HG2  . ARG A 1 158 ? -20.85113 -2.58840  -13.19384 1.000 14.93198 ? 1617 ARG A HG2  1 
ATOM   2401 H  HG3  . ARG A 1 158 ? -20.21982 -3.88712  -12.53036 1.000 14.93198 ? 1617 ARG A HG3  1 
ATOM   2402 H  HD2  . ARG A 1 158 ? -19.77261 -2.75368  -10.61237 1.000 16.37847 ? 1617 ARG A HD2  1 
ATOM   2403 H  HD3  . ARG A 1 158 ? -20.21324 -1.37932  -11.27750 1.000 16.37847 ? 1617 ARG A HD3  1 
ATOM   2404 H  HE   . ARG A 1 158 ? -22.32195 -1.93370  -10.95384 1.000 17.15856 ? 1617 ARG A HE   1 
ATOM   2405 H  HH11 . ARG A 1 158 ? -20.49231 -4.48382  -9.84671  1.000 16.61850 ? 1617 ARG A HH11 1 
ATOM   2406 H  HH12 . ARG A 1 158 ? -21.63029 -5.20962  -9.21661  1.000 16.61850 ? 1617 ARG A HH12 1 
ATOM   2407 H  HH21 . ARG A 1 158 ? -24.00546 -3.08866  -10.06379 1.000 18.38081 ? 1617 ARG A HH21 1 
ATOM   2408 H  HH22 . ARG A 1 158 ? -23.74643 -4.36898  -9.34790  1.000 18.38081 ? 1617 ARG A HH22 1 
ATOM   2409 N  N    . LYS A 1 159 ? -17.25494 -1.63205  -15.73909 1.000 10.61708 ? 1618 LYS A N    1 
ATOM   2410 C  CA   . LYS A 1 159 ? -16.12932 -0.78372  -16.11286 1.000 11.30927 ? 1618 LYS A CA   1 
ATOM   2411 C  C    . LYS A 1 159 ? -15.40178 -0.27416  -14.86919 1.000 10.97239 ? 1618 LYS A C    1 
ATOM   2412 O  O    . LYS A 1 159 ? -14.16536 -0.29913  -14.79611 1.000 11.14872 ? 1618 LYS A O    1 
ATOM   2413 C  CB   . LYS A 1 159 ? -16.64169 0.40013   -16.93902 1.000 12.06726 ? 1618 LYS A CB   1 
ATOM   2414 C  CG   . LYS A 1 159 ? -15.57182 1.41824   -17.32700 1.000 13.58586 ? 1618 LYS A CG   1 
ATOM   2415 C  CD   . LYS A 1 159 ? -16.14597 2.43798   -18.33132 1.000 16.58885 ? 1618 LYS A CD   1 
ATOM   2416 C  CE   . LYS A 1 159 ? -15.08141 3.40148   -18.84828 1.000 21.04728 ? 1618 LYS A CE   1 
ATOM   2417 N  NZ   . LYS A 1 159 ? -15.69633 4.60310   -19.48268 1.000 23.96868 ? 1618 LYS A NZ   1 
ATOM   2418 H  H    . LYS A 1 159 ? -18.00127 -1.40053  -16.09824 1.000 12.74330 ? 1618 LYS A H    1 
ATOM   2419 H  HA   . LYS A 1 159 ? -15.50481 -1.29585  -16.65009 1.000 13.57392 ? 1618 LYS A HA   1 
ATOM   2420 H  HB2  . LYS A 1 159 ? -17.03055 0.05812   -17.75921 1.000 14.48351 ? 1618 LYS A HB2  1 
ATOM   2421 H  HB3  . LYS A 1 159 ? -17.31609 0.86778   -16.42193 1.000 14.48351 ? 1618 LYS A HB3  1 
ATOM   2422 H  HG2  . LYS A 1 159 ? -15.27360 1.89523   -16.53678 1.000 16.30583 ? 1618 LYS A HG2  1 
ATOM   2423 H  HG3  . LYS A 1 159 ? -14.82279 0.96233   -17.74172 1.000 16.30583 ? 1618 LYS A HG3  1 
ATOM   2424 H  HD2  . LYS A 1 159 ? -16.51709 1.96251   -19.09099 1.000 19.90942 ? 1618 LYS A HD2  1 
ATOM   2425 H  HD3  . LYS A 1 159 ? -16.83844 2.95899   -17.89551 1.000 19.90942 ? 1618 LYS A HD3  1 
ATOM   2426 H  HE2  . LYS A 1 159 ? -14.52808 3.69634   -18.10815 1.000 25.25953 ? 1618 LYS A HE2  1 
ATOM   2427 H  HE3  . LYS A 1 159 ? -14.53553 2.95142   -19.51188 1.000 25.25953 ? 1618 LYS A HE3  1 
ATOM   2428 H  HZ1  . LYS A 1 159 ? -16.18602 5.04557   -18.88559 1.000 28.76521 ? 1618 LYS A HZ1  1 
ATOM   2429 H  HZ2  . LYS A 1 159 ? -15.06013 5.14332   -19.79176 1.000 28.76521 ? 1618 LYS A HZ2  1 
ATOM   2430 H  HZ3  . LYS A 1 159 ? -16.21932 4.35615   -20.15914 1.000 28.76521 ? 1618 LYS A HZ3  1 
ATOM   2431 N  N    . GLU A 1 160 ? -16.15913 0.20101   -13.87920 1.000 11.15136 ? 1619 GLU A N    1 
ATOM   2432 C  CA   . GLU A 1 160 ? -15.56635 0.78010   -12.67241 1.000 11.14610 ? 1619 GLU A CA   1 
ATOM   2433 C  C    . GLU A 1 160 ? -14.63011 -0.23187  -12.01738 1.000 10.90922 ? 1619 GLU A C    1 
ATOM   2434 O  O    . GLU A 1 160 ? -13.53036 0.11820   -11.55949 1.000 11.65405 ? 1619 GLU A O    1 
ATOM   2435 C  CB   . GLU A 1 160 ? -16.70618 1.13242   -11.69966 1.000 13.12528 ? 1619 GLU A CB   1 
ATOM   2436 C  CG   . GLU A 1 160 ? -16.34979 1.20101   -10.22443 1.000 14.25436 ? 1619 GLU A CG   1 
ATOM   2437 C  CD   . GLU A 1 160 ? -17.55199 1.51000   -9.33657  1.000 14.37806 ? 1619 GLU A CD   1 
ATOM   2438 O  OE1  . GLU A 1 160 ? -17.32035 2.11461   -8.26196  1.000 15.59399 ? 1619 GLU A OE1  1 
ATOM   2439 O  OE2  . GLU A 1 160 ? -18.71616 1.14965   -9.70641  1.000 15.27027 ? 1619 GLU A OE2  1 
ATOM   2440 H  H    . GLU A 1 160 ? -17.01913 0.20061   -13.88022 1.000 13.38442 ? 1619 GLU A H    1 
ATOM   2441 H  HA   . GLU A 1 160 ? -15.06424 1.58122   -12.88918 1.000 13.37811 ? 1619 GLU A HA   1 
ATOM   2442 H  HB2  . GLU A 1 160 ? -17.05401 2.00326   -11.94778 1.000 15.75313 ? 1619 GLU A HB2  1 
ATOM   2443 H  HB3  . GLU A 1 160 ? -17.39880 0.45973   -11.79273 1.000 15.75313 ? 1619 GLU A HB3  1 
ATOM   2444 H  HG2  . GLU A 1 160 ? -15.98538 0.34569   -9.94778  1.000 17.10803 ? 1619 GLU A HG2  1 
ATOM   2445 H  HG3  . GLU A 1 160 ? -15.69150 1.90085   -10.09108 1.000 17.10803 ? 1619 GLU A HG3  1 
ATOM   2446 N  N    . GLU A 1 161 ? -15.05885 -1.49416  -11.96519 1.000 9.89594  ? 1620 GLU A N    1 
ATOM   2447 C  CA   . GLU A 1 161 ? -14.30291 -2.51470  -11.25373 1.000 9.80383  ? 1620 GLU A CA   1 
ATOM   2448 C  C    . GLU A 1 161 ? -13.05137 -2.92414  -12.02065 1.000 9.15112  ? 1620 GLU A C    1 
ATOM   2449 O  O    . GLU A 1 161 ? -11.97725 -3.06772  -11.42948 1.000 9.88541  ? 1620 GLU A O    1 
ATOM   2450 C  CB   . GLU A 1 161 ? -15.18600 -3.74337  -11.00602 1.000 10.40653 ? 1620 GLU A CB   1 
ATOM   2451 C  CG   . GLU A 1 161 ? -16.37185 -3.47513  -10.08796 1.000 10.80131 ? 1620 GLU A CG   1 
ATOM   2452 C  CD   . GLU A 1 161 ? -17.51542 -4.49024  -10.21214 1.000 10.61972 ? 1620 GLU A CD   1 
ATOM   2453 O  OE1  . GLU A 1 161 ? -17.53253 -5.31154  -11.15327 1.000 11.38559 ? 1620 GLU A OE1  1 
ATOM   2454 O  OE2  . GLU A 1 161 ? -18.42379 -4.42027  -9.34717  1.000 11.94092 ? 1620 GLU A OE2  1 
ATOM   2455 H  H    . GLU A 1 161 ? -15.78139 -1.78132  -12.33270 1.000 11.87793 ? 1620 GLU A H    1 
ATOM   2456 H  HA   . GLU A 1 161 ? -14.02894 -2.14719  -10.39887 1.000 11.76739 ? 1620 GLU A HA   1 
ATOM   2457 H  HB2  . GLU A 1 161 ? -15.53466 -4.05283  -11.85665 1.000 12.49063 ? 1620 GLU A HB2  1 
ATOM   2458 H  HB3  . GLU A 1 161 ? -14.64609 -4.43743  -10.59652 1.000 12.49063 ? 1620 GLU A HB3  1 
ATOM   2459 H  HG2  . GLU A 1 161 ? -16.06213 -3.49452  -9.16894  1.000 12.96437 ? 1620 GLU A HG2  1 
ATOM   2460 H  HG3  . GLU A 1 161 ? -16.73365 -2.59992  -10.29773 1.000 12.96437 ? 1620 GLU A HG3  1 
ATOM   2461 N  N    . ILE A 1 162 ? -13.18088 -3.15720  -13.32914 1.000 9.27745  ? 1621 ILE A N    1 
ATOM   2462 C  CA   . ILE A 1 162 ? -12.02078 -3.59246  -14.10690 1.000 9.39589  ? 1621 ILE A CA   1 
ATOM   2463 C  C    . ILE A 1 162 ? -10.96949 -2.49121  -14.16051 1.000 9.71698  ? 1621 ILE A C    1 
ATOM   2464 O  O    . ILE A 1 162 ? -9.76677  -2.76971  -14.13355 1.000 10.40653 ? 1621 ILE A O    1 
ATOM   2465 C  CB   . ILE A 1 162 ? -12.41868 -4.13134  -15.49437 1.000 10.20388 ? 1621 ILE A CB   1 
ATOM   2466 C  CG1  . ILE A 1 162 ? -11.31810 -5.05048  -16.07113 1.000 10.97502 ? 1621 ILE A CG1  1 
ATOM   2467 C  CG2  . ILE A 1 162 ? -12.72338 -3.03451  -16.47619 1.000 11.32506 ? 1621 ILE A CG2  1 
ATOM   2468 C  CD1  . ILE A 1 162 ? -11.14832 -6.36710  -15.30605 1.000 12.78576 ? 1621 ILE A CD1  1 
ATOM   2469 H  H    . ILE A 1 162 ? -13.90955 -3.07305  -13.77809 1.000 11.13573 ? 1621 ILE A H    1 
ATOM   2470 H  HA   . ILE A 1 162 ? -11.62187 -4.34731  -13.64651 1.000 11.27786 ? 1621 ILE A HA   1 
ATOM   2471 H  HB   . ILE A 1 162 ? -13.23046 -4.64450  -15.35808 1.000 12.24745 ? 1621 ILE A HB   1 
ATOM   2472 H  HG12 . ILE A 1 162 ? -11.54357 -5.26862  -16.98900 1.000 13.17282 ? 1621 ILE A HG12 1 
ATOM   2473 H  HG13 . ILE A 1 162 ? -10.47082 -4.57921  -16.04066 1.000 13.17282 ? 1621 ILE A HG13 1 
ATOM   2474 H  HG21 . ILE A 1 162 ? -13.12953 -3.42244  -17.26704 1.000 13.59287 ? 1621 ILE A HG21 1 
ATOM   2475 H  HG22 . ILE A 1 162 ? -13.33547 -2.40402  -16.06541 1.000 13.59287 ? 1621 ILE A HG22 1 
ATOM   2476 H  HG23 . ILE A 1 162 ? -11.89719 -2.58582  -16.71488 1.000 13.59287 ? 1621 ILE A HG23 1 
ATOM   2477 H  HD11 . ILE A 1 162 ? -10.59573 -6.96787  -15.83009 1.000 15.34571 ? 1621 ILE A HD11 1 
ATOM   2478 H  HD12 . ILE A 1 162 ? -10.72235 -6.18452  -14.45393 1.000 15.34571 ? 1621 ILE A HD12 1 
ATOM   2479 H  HD13 . ILE A 1 162 ? -12.02189 -6.76301  -15.16106 1.000 15.34571 ? 1621 ILE A HD13 1 
ATOM   2480 N  N    . LEU A 1 163 ? -11.39314 -1.22743  -14.22348 1.000 10.24072 ? 1622 LEU A N    1 
ATOM   2481 C  CA   . LEU A 1 163 ? -10.41738 -0.13656  -14.21560 1.000 10.34337 ? 1622 LEU A CA   1 
ATOM   2482 C  C    . LEU A 1 163 ? -9.73101  0.00646   -12.86116 1.000 10.53813 ? 1622 LEU A C    1 
ATOM   2483 O  O    . LEU A 1 163 ? -8.54134  0.33388   -12.80173 1.000 10.99607 ? 1622 LEU A O    1 
ATOM   2484 C  CB   . LEU A 1 163 ? -11.07370 1.17434   -14.62595 1.000 11.17241 ? 1622 LEU A CB   1 
ATOM   2485 C  CG   . LEU A 1 163 ? -11.47413 1.20058   -16.10041 1.000 11.81986 ? 1622 LEU A CG   1 
ATOM   2486 C  CD1  . LEU A 1 163 ? -12.07810 2.57491   -16.42518 1.000 13.42531 ? 1622 LEU A CD1  1 
ATOM   2487 C  CD2  . LEU A 1 163 ? -10.32423 0.90097   -17.05557 1.000 12.22780 ? 1622 LEU A CD2  1 
ATOM   2488 H  H    . LEU A 1 163 ? -12.21578 -0.98108  -14.27009 1.000 12.29166 ? 1622 LEU A H    1 
ATOM   2489 H  HA   . LEU A 1 163 ? -9.73367  -0.34421  -14.87159 1.000 12.41484 ? 1622 LEU A HA   1 
ATOM   2490 H  HB2  . LEU A 1 163 ? -11.87447 1.30537   -14.09446 1.000 13.40969 ? 1622 LEU A HB2  1 
ATOM   2491 H  HB3  . LEU A 1 163 ? -10.44994 1.90079   -14.47073 1.000 13.40969 ? 1622 LEU A HB3  1 
ATOM   2492 H  HG   . LEU A 1 163 ? -12.12339 0.49402   -16.24233 1.000 14.18663 ? 1622 LEU A HG   1 
ATOM   2493 H  HD11 . LEU A 1 163 ? -12.34472 2.59030   -17.35769 1.000 16.11317 ? 1622 LEU A HD11 1 
ATOM   2494 H  HD12 . LEU A 1 163 ? -12.85086 2.72233   -15.85773 1.000 16.11317 ? 1622 LEU A HD12 1 
ATOM   2495 H  HD13 . LEU A 1 163 ? -11.41127 3.25982   -16.26045 1.000 16.11317 ? 1622 LEU A HD13 1 
ATOM   2496 H  HD21 . LEU A 1 163 ? -10.58040 1.16868   -17.95201 1.000 14.67616 ? 1622 LEU A HD21 1 
ATOM   2497 H  HD22 . LEU A 1 163 ? -9.54104  1.39856   -16.77286 1.000 14.67616 ? 1622 LEU A HD22 1 
ATOM   2498 H  HD23 . LEU A 1 163 ? -10.13667 -0.05051  -17.03540 1.000 14.67616 ? 1622 LEU A HD23 1 
ATOM   2499 N  N    A LEU A 1 164 ? -10.45400 -0.21361  -11.75835 0.502 10.93291 ? 1623 LEU A N    1 
ATOM   2500 N  N    B LEU A 1 164 ? -10.45520 -0.21218  -11.76172 0.498 10.93291 ? 1623 LEU A N    1 
ATOM   2501 C  CA   A LEU A 1 164 ? -9.81416  -0.17781  -10.44756 0.502 11.01187 ? 1623 LEU A CA   1 
ATOM   2502 C  CA   B LEU A 1 164 ? -9.81959  -0.17901  -10.45094 0.498 11.01187 ? 1623 LEU A CA   1 
ATOM   2503 C  C    A LEU A 1 164 ? -8.76438  -1.27218  -10.35195 0.502 10.42495 ? 1623 LEU A C    1 
ATOM   2504 C  C    B LEU A 1 164 ? -8.76665  -1.27131  -10.35384 0.498 10.42495 ? 1623 LEU A C    1 
ATOM   2505 O  O    A LEU A 1 164 ? -7.63448  -1.03834  -9.90603  0.502 10.85922 ? 1623 LEU A O    1 
ATOM   2506 O  O    B LEU A 1 164 ? -7.63702  -1.03410  -9.90856  0.498 10.85922 ? 1623 LEU A O    1 
ATOM   2507 C  CB   A LEU A 1 164 ? -10.86309 -0.31710  -9.34738  0.502 12.86209 ? 1623 LEU A CB   1 
ATOM   2508 C  CB   B LEU A 1 164 ? -10.87760 -0.32377  -9.35973  0.498 12.86209 ? 1623 LEU A CB   1 
ATOM   2509 C  CG   A LEU A 1 164 ? -10.46158 -0.06046  -7.89788  0.502 16.49147 ? 1623 LEU A CG   1 
ATOM   2510 C  CG   B LEU A 1 164 ? -10.37810 -0.37513  -7.92450  0.498 16.49147 ? 1623 LEU A CG   1 
ATOM   2511 C  CD1  A LEU A 1 164 ? -9.71876  -1.25104  -7.29837  0.502 18.75753 ? 1623 LEU A CD1  1 
ATOM   2512 C  CD1  B LEU A 1 164 ? -9.76951  0.93210   -7.47343  0.498 18.76542 ? 1623 LEU A CD1  1 
ATOM   2513 C  CD2  A LEU A 1 164 ? -9.62122  1.20288   -7.71620  0.502 17.60476 ? 1623 LEU A CD2  1 
ATOM   2514 C  CD2  B LEU A 1 164 ? -11.55815 -0.73742  -7.01984  0.498 17.59950 ? 1623 LEU A CD2  1 
ATOM   2515 H  H    A LEU A 1 164 ? -11.29729 -0.38180  -11.74518 0.502 13.12229 ? 1623 LEU A H    1 
ATOM   2516 H  H    B LEU A 1 164 ? -11.29892 -0.37836  -11.75045 0.498 13.12229 ? 1623 LEU A H    1 
ATOM   2517 H  HA   A LEU A 1 164 ? -9.37693  0.67862   -10.32008 0.502 13.21704 ? 1623 LEU A HA   1 
ATOM   2518 H  HA   B LEU A 1 164 ? -9.38138  0.67599   -10.31733 0.498 13.21704 ? 1623 LEU A HA   1 
ATOM   2519 H  HB2  A LEU A 1 164 ? -11.57745 0.30781   -9.54760  0.502 15.43731 ? 1623 LEU A HB2  1 
ATOM   2520 H  HB2  B LEU A 1 164 ? -11.47958 0.43412   -9.42392  0.498 15.43731 ? 1623 LEU A HB2  1 
ATOM   2521 H  HB3  A LEU A 1 164 ? -11.19879 -1.22654  -9.38083  0.502 15.43731 ? 1623 LEU A HB3  1 
ATOM   2522 H  HB3  B LEU A 1 164 ? -11.36327 -1.14780  -9.52101  0.498 15.43731 ? 1623 LEU A HB3  1 
ATOM   2523 H  HG   A LEU A 1 164 ? -11.29236 0.07252   -7.41515  0.502 19.79256 ? 1623 LEU A HG   1 
ATOM   2524 H  HG   B LEU A 1 164 ? -9.67514  -1.04045  -7.86039  0.498 19.79256 ? 1623 LEU A HG   1 
ATOM   2525 H  HD11 A LEU A 1 164 ? -9.71212  -1.16517  -6.33220  0.502 22.51183 ? 1623 LEU A HD11 1 
ATOM   2526 H  HD11 B LEU A 1 164 ? -9.00744  1.13694   -8.03752  0.498 22.52131 ? 1623 LEU A HD11 1 
ATOM   2527 H  HD12 A LEU A 1 164 ? -10.17351 -2.06860  -7.55468  0.502 22.51183 ? 1623 LEU A HD12 1 
ATOM   2528 H  HD12 B LEU A 1 164 ? -10.43536 1.63334   -7.54953  0.498 22.52131 ? 1623 LEU A HD12 1 
ATOM   2529 H  HD13 A LEU A 1 164 ? -8.80946  -1.25851  -7.63604  0.502 22.51183 ? 1623 LEU A HD13 1 
ATOM   2530 H  HD13 B LEU A 1 164 ? -9.48410  0.84572   -6.55041  0.498 22.52131 ? 1623 LEU A HD13 1 
ATOM   2531 H  HD21 A LEU A 1 164 ? -9.48495  1.35793   -6.76842  0.502 21.12851 ? 1623 LEU A HD21 1 
ATOM   2532 H  HD21 B LEU A 1 164 ? -11.22078 -0.98577  -6.14497  0.498 21.12219 ? 1623 LEU A HD21 1 
ATOM   2533 H  HD22 A LEU A 1 164 ? -8.76626  1.07963   -8.15750  0.502 21.12851 ? 1623 LEU A HD22 1 
ATOM   2534 H  HD22 B LEU A 1 164 ? -12.14432 0.03153   -6.94227  0.498 21.12219 ? 1623 LEU A HD22 1 
ATOM   2535 H  HD23 A LEU A 1 164 ? -10.09147 1.95431   -8.11005  0.502 21.12851 ? 1623 LEU A HD23 1 
ATOM   2536 H  HD23 B LEU A 1 164 ? -12.03987 -1.48231  -7.41227  0.498 21.12219 ? 1623 LEU A HD23 1 
ATOM   2537 N  N    . ILE A 1 165 ? -9.11668  -2.47857  -10.80141 1.000 9.79593  ? 1624 ILE A N    1 
ATOM   2538 C  CA   . ILE A 1 165 ? -8.16874  -3.58873  -10.74611 1.000 9.91174  ? 1624 ILE A CA   1 
ATOM   2539 C  C    . ILE A 1 165 ? -6.97741  -3.30829  -11.64420 1.000 9.98016  ? 1624 ILE A C    1 
ATOM   2540 O  O    . ILE A 1 165 ? -5.82616  -3.58787  -11.28062 1.000 10.78289 ? 1624 ILE A O    1 
ATOM   2541 C  CB   . ILE A 1 165 ? -8.87791  -4.91123  -11.09938 1.000 10.29073 ? 1624 ILE A CB   1 
ATOM   2542 C  CG1  . ILE A 1 165 ? -9.88435  -5.22633  -9.98674  1.000 10.30915 ? 1624 ILE A CG1  1 
ATOM   2543 C  CG2  . ILE A 1 165 ? -7.87770  -6.04566  -11.31585 1.000 10.89343 ? 1624 ILE A CG2  1 
ATOM   2544 C  CD1  . ILE A 1 165 ? -10.93029 -6.27118  -10.35461 1.000 10.74341 ? 1624 ILE A CD1  1 
ATOM   2545 H  H    . ILE A 1 165 ? -9.88467  -2.67408  -11.13542 1.000 11.75792 ? 1624 ILE A H    1 
ATOM   2546 H  HA   . ILE A 1 165 ? -7.83308  -3.67409  -9.84005  1.000 11.89688 ? 1624 ILE A HA   1 
ATOM   2547 H  HB   . ILE A 1 165 ? -9.35174  -4.81478  -11.94027 1.000 12.35167 ? 1624 ILE A HB   1 
ATOM   2548 H  HG12 . ILE A 1 165 ? -9.39816  -5.55813  -9.21575  1.000 12.37378 ? 1624 ILE A HG12 1 
ATOM   2549 H  HG13 . ILE A 1 165 ? -10.35495 -4.41010  -9.75609  1.000 12.37378 ? 1624 ILE A HG13 1 
ATOM   2550 H  HG21 . ILE A 1 165 ? -8.35504  -6.89004  -11.32526 1.000 13.07491 ? 1624 ILE A HG21 1 
ATOM   2551 H  HG22 . ILE A 1 165 ? -7.42648  -5.91131  -12.16394 1.000 13.07491 ? 1624 ILE A HG22 1 
ATOM   2552 H  HG23 . ILE A 1 165 ? -7.23136  -6.03911  -10.59260 1.000 13.07491 ? 1624 ILE A HG23 1 
ATOM   2553 H  HD11 . ILE A 1 165 ? -11.55293 -6.36801  -9.61716  1.000 12.89489 ? 1624 ILE A HD11 1 
ATOM   2554 H  HD12 . ILE A 1 165 ? -11.40244 -5.97897  -11.14997 1.000 12.89489 ? 1624 ILE A HD12 1 
ATOM   2555 H  HD13 . ILE A 1 165 ? -10.48593 -7.11631  -10.52549 1.000 12.89489 ? 1624 ILE A HD13 1 
ATOM   2556 N  N    A LYS A 1 166 ? -7.23059  -2.74365  -12.82674 0.500 9.84067  ? 1625 LYS A N    1 
ATOM   2557 N  N    B LYS A 1 166 ? -7.23371  -2.74869  -12.82634 0.500 9.98016  ? 1625 LYS A N    1 
ATOM   2558 C  CA   A LYS A 1 166 ? -6.14146  -2.37840  -13.72620 0.500 10.45391 ? 1625 LYS A CA   1 
ATOM   2559 C  CA   B LYS A 1 166 ? -6.16014  -2.36104  -13.73472 0.500 10.60656 ? 1625 LYS A CA   1 
ATOM   2560 C  C    A LYS A 1 166 ? -5.17679  -1.41181  -13.05116 0.500 10.58813 ? 1625 LYS A C    1 
ATOM   2561 C  C    B LYS A 1 166 ? -5.18363  -1.41424  -13.05001 0.500 10.63551 ? 1625 LYS A C    1 
ATOM   2562 O  O    A LYS A 1 166 ? -3.95172  -1.56047  -13.17167 0.500 11.09609 ? 1625 LYS A O    1 
ATOM   2563 O  O    B LYS A 1 166 ? -3.96032  -1.57842  -13.16027 0.500 11.05398 ? 1625 LYS A O    1 
ATOM   2564 C  CB   A LYS A 1 166 ? -6.71349  -1.75397  -15.00100 0.500 11.64878 ? 1625 LYS A CB   1 
ATOM   2565 C  CB   B LYS A 1 166 ? -6.78487  -1.68676  -14.95624 0.500 11.80143 ? 1625 LYS A CB   1 
ATOM   2566 C  CG   A LYS A 1 166 ? -5.67130  -1.39698  -16.06305 0.500 13.09106 ? 1625 LYS A CG   1 
ATOM   2567 C  CG   B LYS A 1 166 ? -5.83378  -1.30150  -16.07916 0.500 13.28846 ? 1625 LYS A CG   1 
ATOM   2568 C  CD   A LYS A 1 166 ? -6.33222  -0.90312  -17.35114 0.500 15.22553 ? 1625 LYS A CD   1 
ATOM   2569 C  CD   B LYS A 1 166 ? -6.64599  -0.71031  -17.23087 0.500 15.26237 ? 1625 LYS A CD   1 
ATOM   2570 C  CE   A LYS A 1 166 ? -5.34295  -0.30376  -18.33687 0.500 17.01259 ? 1625 LYS A CE   1 
ATOM   2571 C  CE   B LYS A 1 166 ? -5.81572  -0.34503  -18.43375 0.500 16.59938 ? 1625 LYS A CE   1 
ATOM   2572 N  NZ   A LYS A 1 166 ? -4.56051  -1.34640  -19.06730 0.500 18.54171 ? 1625 LYS A NZ   1 
ATOM   2573 N  NZ   B LYS A 1 166 ? -6.70959  0.17159   -19.51562 0.500 17.31788 ? 1625 LYS A NZ   1 
ATOM   2574 H  H    A LYS A 1 166 ? -8.01605  -2.56398  -13.12734 0.500 11.81161 ? 1625 LYS A H    1 
ATOM   2575 H  H    B LYS A 1 166 ? -8.02249  -2.58265  -13.12612 0.500 11.97899 ? 1625 LYS A H    1 
ATOM   2576 H  HA   A LYS A 1 166 ? -5.64931  -3.17782  -13.97035 0.500 12.54748 ? 1625 LYS A HA   1 
ATOM   2577 H  HA   B LYS A 1 166 ? -5.66547  -3.14646  -14.01636 0.500 12.73066 ? 1625 LYS A HA   1 
ATOM   2578 H  HB2  A LYS A 1 166 ? -7.33373  -2.38358  -15.40074 0.500 13.98134 ? 1625 LYS A HB2  1 
ATOM   2579 H  HB2  B LYS A 1 166 ? -7.43943  -2.29483  -15.33401 0.500 14.16452 ? 1625 LYS A HB2  1 
ATOM   2580 H  HB3  A LYS A 1 166 ? -7.17824  -0.93683  -14.76186 0.500 13.98134 ? 1625 LYS A HB3  1 
ATOM   2581 H  HB3  B LYS A 1 166 ? -7.22063  -0.87214  -14.66059 0.500 14.16452 ? 1625 LYS A HB3  1 
ATOM   2582 H  HG2  A LYS A 1 166 ? -5.09654  -0.69229  -15.72545 0.500 15.71207 ? 1625 LYS A HG2  1 
ATOM   2583 H  HG2  B LYS A 1 166 ? -5.20119  -0.63687  -15.76453 0.500 15.94894 ? 1625 LYS A HG2  1 
ATOM   2584 H  HG3  A LYS A 1 166 ? -5.14370  -2.18341  -16.27295 0.500 15.71207 ? 1625 LYS A HG3  1 
ATOM   2585 H  HG3  B LYS A 1 166 ? -5.36015  -2.08630  -16.39644 0.500 15.94894 ? 1625 LYS A HG3  1 
ATOM   2586 H  HD2  A LYS A 1 166 ? -6.77135  -1.65039  -17.78664 0.500 18.27343 ? 1625 LYS A HD2  1 
ATOM   2587 H  HD2  B LYS A 1 166 ? -7.30629  -1.36178  -17.51458 0.500 18.31765 ? 1625 LYS A HD2  1 
ATOM   2588 H  HD3  A LYS A 1 166 ? -6.98332  -0.21923  -17.12917 0.500 18.27343 ? 1625 LYS A HD3  1 
ATOM   2589 H  HD3  B LYS A 1 166 ? -7.08730  0.09590   -16.92077 0.500 18.31765 ? 1625 LYS A HD3  1 
ATOM   2590 H  HE2  A LYS A 1 166 ? -5.82726  0.22279   -18.99192 0.500 20.41790 ? 1625 LYS A HE2  1 
ATOM   2591 H  HE2  B LYS A 1 166 ? -5.17850  0.34662   -18.19611 0.500 19.92205 ? 1625 LYS A HE2  1 
ATOM   2592 H  HE3  A LYS A 1 166 ? -4.71714  0.25967   -17.85540 0.500 20.41790 ? 1625 LYS A HE3  1 
ATOM   2593 H  HE3  B LYS A 1 166 ? -5.34768  -1.12908  -18.76101 0.500 19.92205 ? 1625 LYS A HE3  1 
ATOM   2594 H  HZ1  A LYS A 1 166 ? -4.10097  -1.84291  -18.48902 0.500 22.25285 ? 1625 LYS A HZ1  1 
ATOM   2595 H  HZ1  B LYS A 1 166 ? -7.15007  0.89002   -19.22937 0.500 20.78426 ? 1625 LYS A HZ1  1 
ATOM   2596 H  HZ2  A LYS A 1 166 ? -5.11083  -1.87352  -19.52709 0.500 22.25285 ? 1625 LYS A HZ2  1 
ATOM   2597 H  HZ2  B LYS A 1 166 ? -6.22652  0.39426   -20.22917 0.500 20.78426 ? 1625 LYS A HZ2  1 
ATOM   2598 H  HZ3  A LYS A 1 166 ? -3.99157  -0.95998  -19.63217 0.500 22.25285 ? 1625 LYS A HZ3  1 
ATOM   2599 H  HZ3  B LYS A 1 166 ? -7.29802  -0.45403  -19.74895 0.500 20.78426 ? 1625 LYS A HZ3  1 
ATOM   2600 N  N    . ALA A 1 167 ? -5.70727  -0.40844  -12.33933 1.000 10.52233 ? 1626 ALA A N    1 
ATOM   2601 C  CA   . ALA A 1 167 ? -4.84782  0.54130   -11.63916 1.000 10.81184 ? 1626 ALA A CA   1 
ATOM   2602 C  C    . ALA A 1 167 ? -4.05586  -0.14193  -10.53852 1.000 10.60656 ? 1626 ALA A C    1 
ATOM   2603 O  O    . ALA A 1 167 ? -2.87794  0.17501   -10.31738 1.000 11.50403 ? 1626 ALA A O    1 
ATOM   2604 C  CB   . ALA A 1 167 ? -5.69821  1.69338   -11.07717 1.000 11.62246 ? 1626 ALA A CB   1 
ATOM   2605 H  H    . ALA A 1 167 ? -6.55044  -0.26369  -12.25150 1.000 12.62960 ? 1626 ALA A H    1 
ATOM   2606 H  HA   . ALA A 1 167 ? -4.21102  0.91882   -12.26595 1.000 12.97701 ? 1626 ALA A HA   1 
ATOM   2607 H  HB1  . ALA A 1 167 ? -5.11627  2.32390   -10.62474 1.000 13.94975 ? 1626 ALA A HB1  1 
ATOM   2608 H  HB2  . ALA A 1 167 ? -6.15710  2.13362   -11.80963 1.000 13.94975 ? 1626 ALA A HB2  1 
ATOM   2609 H  HB3  . ALA A 1 167 ? -6.34501  1.33217   -10.45100 1.000 13.94975 ? 1626 ALA A HB3  1 
ATOM   2610 N  N    . ALA A 1 168 ? -4.67715  -1.09067  -9.82650  1.000 10.61182 ? 1627 ALA A N    1 
ATOM   2611 C  CA   . ALA A 1 168 ? -3.96150  -1.80750  -8.77889  1.000 10.70920 ? 1627 ALA A CA   1 
ATOM   2612 C  C    . ALA A 1 168 ? -2.84384  -2.67054  -9.35837  1.000 10.53549 ? 1627 ALA A C    1 
ATOM   2613 O  O    . ALA A 1 168 ? -1.73130  -2.70122  -8.81003  1.000 11.19873 ? 1627 ALA A O    1 
ATOM   2614 C  CB   . ALA A 1 168 ? -4.93969  -2.68740  -7.99904  1.000 10.93028 ? 1627 ALA A CB   1 
ATOM   2615 H  H    . ALA A 1 168 ? -5.49643  -1.33008  -9.93171  1.000 12.73698 ? 1627 ALA A H    1 
ATOM   2616 H  HA   . ALA A 1 168 ? -3.56640  -1.16041  -8.17385  1.000 12.85384 ? 1627 ALA A HA   1 
ATOM   2617 H  HB1  . ALA A 1 168 ? -4.45252  -3.16969  -7.31278  1.000 13.11913 ? 1627 ALA A HB1  1 
ATOM   2618 H  HB2  . ALA A 1 168 ? -5.61518  -2.12354  -7.59078  1.000 13.11913 ? 1627 ALA A HB2  1 
ATOM   2619 H  HB3  . ALA A 1 168 ? -5.35730  -3.31400  -8.61049  1.000 13.11913 ? 1627 ALA A HB3  1 
ATOM   2620 N  N    . LYS A 1 169 ? -3.08867  -3.31566  -10.49714 1.000 10.32494 ? 1628 LYS A N    1 
ATOM   2621 C  CA   . LYS A 1 169 ? -2.04094  -4.09881  -11.14416 1.000 11.38033 ? 1628 LYS A CA   1 
ATOM   2622 C  C    . LYS A 1 169 ? -0.90609  -3.21082  -11.63910 1.000 12.57521 ? 1628 LYS A C    1 
ATOM   2623 O  O    . LYS A 1 169 ? 0.26733   -3.61702  -11.59770 1.000 13.05685 ? 1628 LYS A O    1 
ATOM   2624 C  CB   . LYS A 1 169 ? -2.61758  -4.90059  -12.30014 1.000 11.28821 ? 1628 LYS A CB   1 
ATOM   2625 C  CG   . LYS A 1 169 ? -3.50201  -6.06190  -11.85223 1.000 10.58287 ? 1628 LYS A CG   1 
ATOM   2626 C  CD   . LYS A 1 169 ? -3.92521  -6.91312  -13.02356 1.000 10.80658 ? 1628 LYS A CD   1 
ATOM   2627 C  CE   . LYS A 1 169 ? -4.71576  -8.15893  -12.56464 1.000 10.63024 ? 1628 LYS A CE   1 
ATOM   2628 N  NZ   . LYS A 1 169 ? -5.02510  -9.07368  -13.69791 1.000 10.77236 ? 1628 LYS A NZ   1 
ATOM   2629 H  H    . LYS A 1 169 ? -3.84285  -3.31623  -10.91042 1.000 12.39273 ? 1628 LYS A H    1 
ATOM   2630 H  HA   . LYS A 1 169 ? -1.67940  -4.72484  -10.49740 1.000 13.65920 ? 1628 LYS A HA   1 
ATOM   2631 H  HB2  . LYS A 1 169 ? -3.15630  -4.31180  -12.85151 1.000 13.54865 ? 1628 LYS A HB2  1 
ATOM   2632 H  HB3  . LYS A 1 169 ? -1.88680  -5.26727  -12.82207 1.000 13.54865 ? 1628 LYS A HB3  1 
ATOM   2633 H  HG2  . LYS A 1 169 ? -3.00952  -6.62053  -11.23071 1.000 12.70224 ? 1628 LYS A HG2  1 
ATOM   2634 H  HG3  . LYS A 1 169 ? -4.29946  -5.71280  -11.42432 1.000 12.70224 ? 1628 LYS A HG3  1 
ATOM   2635 H  HD2  . LYS A 1 169 ? -4.49380  -6.39102  -13.61094 1.000 12.97069 ? 1628 LYS A HD2  1 
ATOM   2636 H  HD3  . LYS A 1 169 ? -3.13752  -7.21231  -13.50412 1.000 12.97069 ? 1628 LYS A HD3  1 
ATOM   2637 H  HE2  . LYS A 1 169 ? -4.18870  -8.64963  -11.91478 1.000 12.75909 ? 1628 LYS A HE2  1 
ATOM   2638 H  HE3  . LYS A 1 169 ? -5.55386  -7.87608  -12.16654 1.000 12.75909 ? 1628 LYS A HE3  1 
ATOM   2639 H  HZ1  . LYS A 1 169 ? -5.47834  -8.63660  -14.32691 1.000 12.92963 ? 1628 LYS A HZ1  1 
ATOM   2640 H  HZ2  . LYS A 1 169 ? -4.27056  -9.38715  -14.05076 1.000 12.92963 ? 1628 LYS A HZ2  1 
ATOM   2641 H  HZ3  . LYS A 1 169 ? -5.51612  -9.75834  -13.41115 1.000 12.92963 ? 1628 LYS A HZ3  1 
ATOM   2642 N  N    . ALA A 1 170 ? -1.22203  -1.99512  -12.09199 1.000 12.72260 ? 1629 ALA A N    1 
ATOM   2643 C  CA   . ALA A 1 170 ? -0.17195  -1.07743  -12.52218 1.000 12.99895 ? 1629 ALA A CA   1 
ATOM   2644 C  C    . ALA A 1 170 ? 0.71101   -0.66285  -11.35601 1.000 13.69377 ? 1629 ALA A C    1 
ATOM   2645 O  O    . ALA A 1 170 ? 1.89026   -0.33707  -11.56345 1.000 15.10972 ? 1629 ALA A O    1 
ATOM   2646 C  CB   . ALA A 1 170 ? -0.78385  0.14539   -13.19610 1.000 13.75167 ? 1629 ALA A CB   1 
ATOM   2647 H  H    . ALA A 1 170 ? -2.02142  -1.68497  -12.15825 1.000 15.26992 ? 1629 ALA A H    1 
ATOM   2648 H  HA   . ALA A 1 170 ? 0.38714   -1.52265  -13.17800 1.000 15.60153 ? 1629 ALA A HA   1 
ATOM   2649 H  HB1  . ALA A 1 170 ? -0.07142  0.74054   -13.47742 1.000 16.50480 ? 1629 ALA A HB1  1 
ATOM   2650 H  HB2  . ALA A 1 170 ? -1.29778  -0.14275  -13.96665 1.000 16.50480 ? 1629 ALA A HB2  1 
ATOM   2651 H  HB3  . ALA A 1 170 ? -1.36264  0.59834   -12.56306 1.000 16.50480 ? 1629 ALA A HB3  1 
ATOM   2652 N  N    . ARG A 1 171 ? 0.19183   -0.70076  -10.13311 1.000 13.23582 ? 1630 ARG A N    1 
ATOM   2653 C  CA   . ARG A 1 171 ? 0.96909   -0.42128  -8.92886  1.000 13.47006 ? 1630 ARG A CA   1 
ATOM   2654 C  C    . ARG A 1 171 ? 1.65109   -1.67291  -8.37373  1.000 13.13054 ? 1630 ARG A C    1 
ATOM   2655 O  O    . ARG A 1 171 ? 2.23712   -1.61211  -7.28746  1.000 15.03866 ? 1630 ARG A O    1 
ATOM   2656 C  CB   . ARG A 1 171 ? 0.08853   0.25057   -7.85975  1.000 15.44924 ? 1630 ARG A CB   1 
ATOM   2657 C  CG   . ARG A 1 171 ? -0.35046  1.68801   -8.21964  1.000 17.38105 ? 1630 ARG A CG   1 
ATOM   2658 C  CD   . ARG A 1 171 ? 0.75522   2.70592   -7.96772  1.000 20.25245 ? 1630 ARG A CD   1 
ATOM   2659 N  NE   . ARG A 1 171 ? 1.09256   2.70197   -6.55174  1.000 22.48429 ? 1630 ARG A NE   1 
ATOM   2660 C  CZ   . ARG A 1 171 ? 2.22142   3.16852   -6.04205  1.000 23.98974 ? 1630 ARG A CZ   1 
ATOM   2661 N  NH1  . ARG A 1 171 ? 3.13619   3.73649   -6.80252  1.000 25.08197 ? 1630 ARG A NH1  1 
ATOM   2662 N  NH2  . ARG A 1 171 ? 2.43910   3.05054   -4.73658  1.000 24.23714 ? 1630 ARG A NH2  1 
ATOM   2663 H  H    . ARG A 1 171 ? -0.63083  -0.89107  -9.96999  1.000 15.88578 ? 1630 ARG A H    1 
ATOM   2664 H  HA   . ARG A 1 171 ? 1.66778   0.21507   -9.14747  1.000 16.16687 ? 1630 ARG A HA   1 
ATOM   2665 H  HB2  . ARG A 1 171 ? -0.71353  -0.28131  -7.73850  1.000 18.54189 ? 1630 ARG A HB2  1 
ATOM   2666 H  HB3  . ARG A 1 171 ? 0.58689   0.29355   -7.02868  1.000 18.54189 ? 1630 ARG A HB3  1 
ATOM   2667 H  HG2  . ARG A 1 171 ? -0.58548  1.72365   -9.16006  1.000 20.86006 ? 1630 ARG A HG2  1 
ATOM   2668 H  HG3  . ARG A 1 171 ? -1.11612  1.93296   -7.67682  1.000 20.86006 ? 1630 ARG A HG3  1 
ATOM   2669 H  HD2  . ARG A 1 171 ? 1.54424   2.47005   -8.48028  1.000 24.30573 ? 1630 ARG A HD2  1 
ATOM   2670 H  HD3  . ARG A 1 171 ? 0.45073   3.59261   -8.21663  1.000 24.30573 ? 1630 ARG A HD3  1 
ATOM   2671 H  HE   . ARG A 1 171 ? 0.51565   2.37205   -6.00591  1.000 26.98395 ? 1630 ARG A HE   1 
ATOM   2672 H  HH11 . ARG A 1 171 ? 3.00602   3.81023   -7.64941  1.000 30.10116 ? 1630 ARG A HH11 1 
ATOM   2673 H  HH12 . ARG A 1 171 ? 3.86315   4.03330   -6.45176  1.000 30.10116 ? 1630 ARG A HH12 1 
ATOM   2674 H  HH21 . ARG A 1 171 ? 1.85034   2.67496   -4.23469  1.000 29.08736 ? 1630 ARG A HH21 1 
ATOM   2675 H  HH22 . ARG A 1 171 ? 3.16875   3.34976   -4.39354  1.000 29.08736 ? 1630 ARG A HH22 1 
ATOM   2676 N  N    . GLY A 1 172 ? 1.59690   -2.79560  -9.09485  1.000 12.67259 ? 1631 GLY A N    1 
ATOM   2677 C  CA   . GLY A 1 172 ? 2.25029   -4.01406  -8.65552  1.000 13.62797 ? 1631 GLY A CA   1 
ATOM   2678 C  C    . GLY A 1 172 ? 1.56078   -4.75778  -7.53137  1.000 13.48585 ? 1631 GLY A C    1 
ATOM   2679 O  O    . GLY A 1 172 ? 2.20475   -5.58045  -6.87115  1.000 14.62282 ? 1631 GLY A O    1 
ATOM   2680 H  H    . GLY A 1 172 ? 1.18412   -2.87143  -9.84549  1.000 15.20991 ? 1631 GLY A H    1 
ATOM   2681 H  HA2  . GLY A 1 172 ? 2.31318   -4.61903  -9.41114  1.000 16.35636 ? 1631 GLY A HA2  1 
ATOM   2682 H  HA3  . GLY A 1 172 ? 3.14491   -3.79174  -8.35366  1.000 16.35636 ? 1631 GLY A HA3  1 
ATOM   2683 N  N    . LEU A 1 173 ? 0.27575   -4.49944  -7.28254  1.000 12.34624 ? 1632 LEU A N    1 
ATOM   2684 C  CA   . LEU A 1 173 ? -0.36810  -5.14767  -6.16715  1.000 12.15674 ? 1632 LEU A CA   1 
ATOM   2685 C  C    . LEU A 1 173 ? -0.80962  -6.55888  -6.54891  1.000 10.80395 ? 1632 LEU A C    1 
ATOM   2686 O  O    . LEU A 1 173 ? -1.17514  -6.81716  -7.70282  1.000 11.60667 ? 1632 LEU A O    1 
ATOM   2687 C  CB   . LEU A 1 173 ? -1.59595  -4.36611  -5.75625  1.000 13.30688 ? 1632 LEU A CB   1 
ATOM   2688 C  CG   . LEU A 1 173 ? -1.27478  -2.94559  -5.30851  1.000 15.05182 ? 1632 LEU A CG   1 
ATOM   2689 C  CD1  . LEU A 1 173 ? -2.53897  -2.20832  -4.86246  1.000 15.51240 ? 1632 LEU A CD1  1 
ATOM   2690 C  CD2  . LEU A 1 173 ? -0.22805  -2.88070  -4.21152  1.000 16.67570 ? 1632 LEU A CD2  1 
ATOM   2691 H  H    . LEU A 1 173 ? -0.22224  -3.96624  -7.73785  1.000 14.81828 ? 1632 LEU A H    1 
ATOM   2692 H  HA   . LEU A 1 173 ? 0.25192   -5.19738  -5.42284  1.000 14.59089 ? 1632 LEU A HA   1 
ATOM   2693 H  HB2  . LEU A 1 173 ? -2.20184  -4.31279  -6.51187  1.000 15.97105 ? 1632 LEU A HB2  1 
ATOM   2694 H  HB3  . LEU A 1 173 ? -2.02673  -4.82349  -5.01723  1.000 15.97105 ? 1632 LEU A HB3  1 
ATOM   2695 H  HG   . LEU A 1 173 ? -0.89830  -2.49628  -6.08135  1.000 18.06499 ? 1632 LEU A HG   1 
ATOM   2696 H  HD11 . LEU A 1 173 ? -2.29964  -1.30988  -4.58601  1.000 18.61768 ? 1632 LEU A HD11 1 
ATOM   2697 H  HD12 . LEU A 1 173 ? -3.16153  -2.17101  -5.60537  1.000 18.61768 ? 1632 LEU A HD12 1 
ATOM   2698 H  HD13 . LEU A 1 173 ? -2.93858  -2.68752  -4.11977  1.000 18.61768 ? 1632 LEU A HD13 1 
ATOM   2699 H  HD21 . LEU A 1 173 ? -0.20548  -1.98112  -3.84937  1.000 20.01364 ? 1632 LEU A HD21 1 
ATOM   2700 H  HD22 . LEU A 1 173 ? -0.46234  -3.51241  -3.51370  1.000 20.01364 ? 1632 LEU A HD22 1 
ATOM   2701 H  HD23 . LEU A 1 173 ? 0.63709   -3.10805  -4.58667  1.000 20.01364 ? 1632 LEU A HD23 1 
ATOM   2702 N  N    . PRO A 1 174 ? -0.77806  -7.48485  -5.58919  1.000 10.30126 ? 1633 PRO A N    1 
ATOM   2703 C  CA   . PRO A 1 174 ? -1.10775  -8.88413  -5.89475  1.000 9.68276  ? 1633 PRO A CA   1 
ATOM   2704 C  C    . PRO A 1 174 ? -2.61174  -9.10662  -5.87176  1.000 10.11965 ? 1633 PRO A C    1 
ATOM   2705 O  O    . PRO A 1 174 ? -3.19734  -9.50459  -4.85855  1.000 10.89343 ? 1633 PRO A O    1 
ATOM   2706 C  CB   . PRO A 1 174 ? -0.36802  -9.65313  -4.80201  1.000 10.19335 ? 1633 PRO A CB   1 
ATOM   2707 C  CG   . PRO A 1 174 ? -0.34833  -8.71245  -3.61879  1.000 11.04345 ? 1633 PRO A CG   1 
ATOM   2708 C  CD   . PRO A 1 174 ? -0.26117  -7.33230  -4.21704  1.000 11.45929 ? 1633 PRO A CD   1 
ATOM   2709 H  HA   . PRO A 1 174 ? -0.75575  -9.16725  -6.75314  1.000 11.62211 ? 1633 PRO A HA   1 
ATOM   2710 H  HB2  . PRO A 1 174 ? -0.84619  -10.46996 -4.58976  1.000 12.23481 ? 1633 PRO A HB2  1 
ATOM   2711 H  HB3  . PRO A 1 174 ? 0.53244   -9.86257  -5.09559  1.000 12.23481 ? 1633 PRO A HB3  1 
ATOM   2712 H  HG2  . PRO A 1 174 ? -1.16252  -8.81505  -3.10162  1.000 13.25493 ? 1633 PRO A HG2  1 
ATOM   2713 H  HG3  . PRO A 1 174 ? 0.42397   -8.89807  -3.06202  1.000 13.25493 ? 1633 PRO A HG3  1 
ATOM   2714 H  HD2  . PRO A 1 174 ? -0.80932  -6.70918  -3.71488  1.000 13.75394 ? 1633 PRO A HD2  1 
ATOM   2715 H  HD3  . PRO A 1 174 ? 0.65920   -7.02641  -4.23280  1.000 13.75394 ? 1633 PRO A HD3  1 
ATOM   2716 N  N    . VAL A 1 175 ? -3.23238  -8.82954  -7.01366  1.000 9.86962  ? 1634 VAL A N    1 
ATOM   2717 C  CA   . VAL A 1 175 ? -4.66543  -9.01426  -7.20301  1.000 9.51695  ? 1634 VAL A CA   1 
ATOM   2718 C  C    . VAL A 1 175 ? -4.86547  -9.68962  -8.54762  1.000 8.94846  ? 1634 VAL A C    1 
ATOM   2719 O  O    . VAL A 1 175 ? -4.22666  -9.33840  -9.54766  1.000 10.42232 ? 1634 VAL A O    1 
ATOM   2720 C  CB   . VAL A 1 175 ? -5.43602  -7.67923  -7.13986  1.000 10.02228 ? 1634 VAL A CB   1 
ATOM   2721 C  CG1  . VAL A 1 175 ? -4.87288  -6.64330  -8.03428  1.000 10.66709 ? 1634 VAL A CG1  1 
ATOM   2722 C  CG2  . VAL A 1 175 ? -6.92831  -7.88963  -7.39765  1.000 10.44864 ? 1634 VAL A CG2  1 
ATOM   2723 H  H    . VAL A 1 175 ? -2.83279  -8.52509  -7.71169  1.000 11.84635 ? 1634 VAL A H    1 
ATOM   2724 H  HA   . VAL A 1 175 ? -5.01706  -9.58741  -6.50389  1.000 11.42314 ? 1634 VAL A HA   1 
ATOM   2725 H  HB   . VAL A 1 175 ? -5.33343  -7.33706  -6.23803  1.000 12.02953 ? 1634 VAL A HB   1 
ATOM   2726 H  HG11 . VAL A 1 175 ? -5.41327  -5.84056  -7.96731  1.000 12.80330 ? 1634 VAL A HG11 1 
ATOM   2727 H  HG12 . VAL A 1 175 ? -3.96169  -6.45233  -7.76193  1.000 12.80330 ? 1634 VAL A HG12 1 
ATOM   2728 H  HG13 . VAL A 1 175 ? -4.88317  -6.97386  -8.94616  1.000 12.80330 ? 1634 VAL A HG13 1 
ATOM   2729 H  HG21 . VAL A 1 175 ? -7.38740  -7.04003  -7.30651  1.000 12.54117 ? 1634 VAL A HG21 1 
ATOM   2730 H  HG22 . VAL A 1 175 ? -7.04792  -8.23556  -8.29594  1.000 12.54117 ? 1634 VAL A HG22 1 
ATOM   2731 H  HG23 . VAL A 1 175 ? -7.27431  -8.52369  -6.75022  1.000 12.54117 ? 1634 VAL A HG23 1 
ATOM   2732 N  N    . THR A 1 176 ? -5.75463  -10.68170 -8.56131  1.000 9.02215  ? 1635 THR A N    1 
ATOM   2733 C  CA   . THR A 1 176 ? -6.20035  -11.30363 -9.79457  1.000 9.27218  ? 1635 THR A CA   1 
ATOM   2734 C  C    . THR A 1 176 ? -7.72137  -11.23834 -9.82970  1.000 8.80897  ? 1635 THR A C    1 
ATOM   2735 O  O    . THR A 1 176 ? -8.36363  -10.88422 -8.83418  1.000 9.11953  ? 1635 THR A O    1 
ATOM   2736 C  CB   . THR A 1 176 ? -5.74076  -12.76070 -9.91235  1.000 10.08807 ? 1635 THR A CB   1 
ATOM   2737 O  OG1  . THR A 1 176 ? -6.12466  -13.49565 -8.74946  1.000 10.79342 ? 1635 THR A OG1  1 
ATOM   2738 C  CG2  . THR A 1 176 ? -4.20531  -12.83679 -10.06227 1.000 10.56181 ? 1635 THR A CG2  1 
ATOM   2739 H  H    . THR A 1 176 ? -6.11630  -11.01291 -7.85484  1.000 10.82938 ? 1635 THR A H    1 
ATOM   2740 H  HA   . THR A 1 176 ? -5.83094  -10.82032 -10.55011 1.000 11.12942 ? 1635 THR A HA   1 
ATOM   2741 H  HB   . THR A 1 176 ? -6.15415  -13.15585 -10.69585 1.000 12.10848 ? 1635 THR A HB   1 
ATOM   2742 H  HG1  . THR A 1 176 ? -5.87594  -14.29491 -8.81963  1.000 12.95490 ? 1635 THR A HG1  1 
ATOM   2743 H  HG21 . THR A 1 176 ? -3.92435  -13.76250 -10.13310 1.000 12.67697 ? 1635 THR A HG21 1 
ATOM   2744 H  HG22 . THR A 1 176 ? -3.92589  -12.36108 -10.86009 1.000 12.67697 ? 1635 THR A HG22 1 
ATOM   2745 H  HG23 . THR A 1 176 ? -3.77631  -12.43581 -9.29021  1.000 12.67697 ? 1635 THR A HG23 1 
ATOM   2746 N  N    . CYS A 1 177 ? -8.29471  -11.55258 -10.98822 1.000 8.94583  ? 1636 CYS A N    1 
ATOM   2747 C  CA   . CYS A 1 177 ? -9.74775  -11.50254 -11.10165 1.000 8.89846  ? 1636 CYS A CA   1 
ATOM   2748 C  C    . CYS A 1 177 ? -10.24671 -12.45750 -12.17121 1.000 8.55631  ? 1636 CYS A C    1 
ATOM   2749 O  O    . CYS A 1 177 ? -9.49080  -12.98301 -13.00177 1.000 8.94846  ? 1636 CYS A O    1 
ATOM   2750 C  CB   . CYS A 1 177 ? -10.21095 -10.06487 -11.38800 1.000 9.46958  ? 1636 CYS A CB   1 
ATOM   2751 S  SG   . CYS A 1 177 ? -9.81137  -9.44517  -13.04708 1.000 10.43548 ? 1636 CYS A SG   1 
ATOM   2752 H  H    . CYS A 1 177 ? -7.87606  -11.79048 -11.70078 1.000 10.73779 ? 1636 CYS A H    1 
ATOM   2753 H  HA   . CYS A 1 177 ? -10.13047 -11.81050 -10.26524 1.000 10.68094 ? 1636 CYS A HA   1 
ATOM   2754 H  HB2  . CYS A 1 177 ? -11.17506 -10.02757 -11.28806 1.000 11.36629 ? 1636 CYS A HB2  1 
ATOM   2755 H  HB3  . CYS A 1 177 ? -9.78778  -9.47278  -10.74672 1.000 11.36629 ? 1636 CYS A HB3  1 
ATOM   2756 H  HG   . CYS A 1 177 ? -10.23589 -8.32844  -13.15973 1.000 12.52537 ? 1636 CYS A HG   1 
ATOM   2757 N  N    . GLU A 1 178 ? -11.56030 -12.66374 -12.15256 1.000 8.40892  ? 1637 GLU A N    1 
ATOM   2758 C  CA   . GLU A 1 178 ? -12.24209 -13.46561 -13.14603 1.000 8.94846  ? 1637 GLU A CA   1 
ATOM   2759 C  C    . GLU A 1 178 ? -13.46877 -12.70102 -13.62851 1.000 8.39840  ? 1637 GLU A C    1 
ATOM   2760 O  O    . GLU A 1 178 ? -13.97834 -11.80332 -12.94609 1.000 9.57222  ? 1637 GLU A O    1 
ATOM   2761 C  CB   . GLU A 1 178 ? -12.69730 -14.80455 -12.55319 1.000 9.73540  ? 1637 GLU A CB   1 
ATOM   2762 C  CG   . GLU A 1 178 ? -13.88509 -14.62626 -11.63165 1.000 9.79856  ? 1637 GLU A CG   1 
ATOM   2763 C  CD   . GLU A 1 178 ? -14.07934 -15.68360 -10.55585 1.000 10.21967 ? 1637 GLU A CD   1 
ATOM   2764 O  OE1  . GLU A 1 178 ? -13.12382 -16.39038 -10.17532 1.000 10.71709 ? 1637 GLU A OE1  1 
ATOM   2765 O  OE2  . GLU A 1 178 ? -15.22623 -15.74804 -10.02980 1.000 10.83553 ? 1637 GLU A OE2  1 
ATOM   2766 H  H    . GLU A 1 178 ? -12.08694 -12.33818 -11.55568 1.000 10.09351 ? 1637 GLU A H    1 
ATOM   2767 H  HA   . GLU A 1 178 ? -11.65078 -13.63558 -13.89593 1.000 10.74095 ? 1637 GLU A HA   1 
ATOM   2768 H  HB2  . GLU A 1 178 ? -12.95487 -15.40263 -13.27211 1.000 11.68527 ? 1637 GLU A HB2  1 
ATOM   2769 H  HB3  . GLU A 1 178 ? -11.96974 -15.19328 -12.04285 1.000 11.68527 ? 1637 GLU A HB3  1 
ATOM   2770 H  HG2  . GLU A 1 178 ? -13.78836 -13.77467 -11.17741 1.000 11.76107 ? 1637 GLU A HG2  1 
ATOM   2771 H  HG3  . GLU A 1 178 ? -14.68914 -14.62341 -12.17424 1.000 11.76107 ? 1637 GLU A HG3  1 
ATOM   2772 N  N    . VAL A 1 179 ? -13.94300 -13.08673 -14.81281 1.000 8.54841  ? 1638 VAL A N    1 
ATOM   2773 C  CA   . VAL A 1 179 ? -15.15033 -12.53718 -15.41319 1.000 8.40629  ? 1638 VAL A CA   1 
ATOM   2774 C  C    . VAL A 1 179 ? -16.03541 -13.68492 -15.86853 1.000 8.95372  ? 1638 VAL A C    1 
ATOM   2775 O  O    . VAL A 1 179 ? -15.54450 -14.68418 -16.41035 1.000 9.86962  ? 1638 VAL A O    1 
ATOM   2776 C  CB   . VAL A 1 179 ? -14.81465 -11.59355 -16.58191 1.000 9.15375  ? 1638 VAL A CB   1 
ATOM   2777 C  CG1  . VAL A 1 179 ? -16.05439 -11.19101 -17.35034 1.000 10.35389 ? 1638 VAL A CG1  1 
ATOM   2778 C  CG2  . VAL A 1 179 ? -14.11991 -10.35684 -16.03709 1.000 9.19849  ? 1638 VAL A CG2  1 
ATOM   2779 H  H    . VAL A 1 179 ? -13.56717 -13.68631 -15.30153 1.000 10.26089 ? 1638 VAL A H    1 
ATOM   2780 H  HA   . VAL A 1 179 ? -15.64299 -12.03107 -14.74833 1.000 10.09035 ? 1638 VAL A HA   1 
ATOM   2781 H  HB   . VAL A 1 179 ? -14.22983 -12.05867 -17.20041 1.000 10.98730 ? 1638 VAL A HB   1 
ATOM   2782 H  HG11 . VAL A 1 179 ? -15.84011 -10.43853 -17.92372 1.000 12.42747 ? 1638 VAL A HG11 1 
ATOM   2783 H  HG12 . VAL A 1 179 ? -16.35081 -11.94232 -17.88753 1.000 12.42747 ? 1638 VAL A HG12 1 
ATOM   2784 H  HG13 . VAL A 1 179 ? -16.74850 -10.94013 -16.72092 1.000 12.42747 ? 1638 VAL A HG13 1 
ATOM   2785 H  HG21 . VAL A 1 179 ? -13.99808 -9.71959  -16.75818 1.000 11.04099 ? 1638 VAL A HG21 1 
ATOM   2786 H  HG22 . VAL A 1 179 ? -14.67037 -9.96658  -15.34025 1.000 11.04099 ? 1638 VAL A HG22 1 
ATOM   2787 H  HG23 . VAL A 1 179 ? -13.25812 -10.61328 -15.67315 1.000 11.04099 ? 1638 VAL A HG23 1 
ATOM   2788 N  N    . ALA A 1 180 ? -17.33763 -13.53103 -15.65218 1.000 9.10374  ? 1639 ALA A N    1 
ATOM   2789 C  CA   . ALA A 1 180 ? -18.32941 -14.53847 -16.01306 1.000 9.31429  ? 1639 ALA A CA   1 
ATOM   2790 C  C    . ALA A 1 180 ? -18.95688 -14.22023 -17.36058 1.000 9.60117  ? 1639 ALA A C    1 
ATOM   2791 O  O    . ALA A 1 180 ? -19.03194 -13.06754 -17.77637 1.000 9.96437  ? 1639 ALA A O    1 
ATOM   2792 C  CB   . ALA A 1 180 ? -19.44898 -14.58277 -14.98212 1.000 9.42747  ? 1639 ALA A CB   1 
ATOM   2793 H  H    . ALA A 1 180 ? -17.68264 -12.83274 -15.28755 1.000 10.92729 ? 1639 ALA A H    1 
ATOM   2794 H  HA   . ALA A 1 180 ? -17.89664 -15.40557 -16.05482 1.000 11.17995 ? 1639 ALA A HA   1 
ATOM   2795 H  HB1  . ALA A 1 180 ? -20.07556 -15.28186 -15.22620 1.000 11.31576 ? 1639 ALA A HB1  1 
ATOM   2796 H  HB2  . ALA A 1 180 ? -19.06793 -14.76985 -14.10994 1.000 11.31576 ? 1639 ALA A HB2  1 
ATOM   2797 H  HB3  . ALA A 1 180 ? -19.90011 -13.72416 -14.96873 1.000 11.31576 ? 1639 ALA A HB3  1 
ATOM   2798 N  N    . PRO A 1 181 ? -19.42604 -15.23823 -18.06698 1.000 10.13281 ? 1640 PRO A N    1 
ATOM   2799 C  CA   . PRO A 1 181 ? -19.86748 -15.01499 -19.44337 1.000 10.05912 ? 1640 PRO A CA   1 
ATOM   2800 C  C    . PRO A 1 181 ? -21.04544 -14.09233 -19.56607 1.000 10.10386 ? 1640 PRO A C    1 
ATOM   2801 O  O    . PRO A 1 181 ? -21.14879 -13.38586 -20.57543 1.000 10.23019 ? 1640 PRO A O    1 
ATOM   2802 C  CB   . PRO A 1 181 ? -20.20926 -16.42718 -19.95645 1.000 11.59615 ? 1640 PRO A CB   1 
ATOM   2803 C  CG   . PRO A 1 181 ? -19.48525 -17.29263 -19.11280 1.000 13.00421 ? 1640 PRO A CG   1 
ATOM   2804 C  CD   . PRO A 1 181 ? -19.36279 -16.67653 -17.74284 1.000 11.14873 ? 1640 PRO A CD   1 
ATOM   2805 H  HA   . PRO A 1 181 ? -19.12542 -14.65836 -19.95627 1.000 12.07374 ? 1640 PRO A HA   1 
ATOM   2806 H  HB2  . PRO A 1 181 ? -21.16343 -16.58554 -19.88307 1.000 13.91817 ? 1640 PRO A HB2  1 
ATOM   2807 H  HB3  . PRO A 1 181 ? -19.92713 -16.52270 -20.87958 1.000 13.91817 ? 1640 PRO A HB3  1 
ATOM   2808 H  HG2  . PRO A 1 181 ? -19.95789 -18.13759 -19.05331 1.000 15.60784 ? 1640 PRO A HG2  1 
ATOM   2809 H  HG3  . PRO A 1 181 ? -18.60327 -17.43181 -19.49180 1.000 15.60784 ? 1640 PRO A HG3  1 
ATOM   2810 H  HD2  . PRO A 1 181 ? -20.09888 -16.94179 -17.16951 1.000 13.38127 ? 1640 PRO A HD2  1 
ATOM   2811 H  HD3  . PRO A 1 181 ? -18.51784 -16.90757 -17.32622 1.000 13.38127 ? 1640 PRO A HD3  1 
ATOM   2812 N  N    . HIS A 1 182 ? -21.95790 -14.09394 -18.59459 1.000 10.13018 ? 1641 HIS A N    1 
ATOM   2813 C  CA   . HIS A 1 182 ? -23.08322 -13.18353 -18.71800 1.000 10.72236 ? 1641 HIS A CA   1 
ATOM   2814 C  C    . HIS A 1 182 ? -22.66349 -11.72521 -18.70538 1.000 10.62235 ? 1641 HIS A C    1 
ATOM   2815 O  O    . HIS A 1 182 ? -23.39558 -10.90247 -19.25886 1.000 11.24610 ? 1641 HIS A O    1 
ATOM   2816 C  CB   . HIS A 1 182 ? -24.16001 -13.45325 -17.68396 1.000 10.30389 ? 1641 HIS A CB   1 
ATOM   2817 C  CG   . HIS A 1 182 ? -23.66197 -13.82994 -16.33124 1.000 9.84857  ? 1641 HIS A CG   1 
ATOM   2818 N  ND1  . HIS A 1 182 ? -23.12608 -15.07068 -16.04497 1.000 10.09860 ? 1641 HIS A ND1  1 
ATOM   2819 C  CD2  . HIS A 1 182 ? -23.66630 -13.14737 -15.16728 1.000 9.97227  ? 1641 HIS A CD2  1 
ATOM   2820 C  CE1  . HIS A 1 182 ? -22.83231 -15.12855 -14.76181 1.000 9.38536  ? 1641 HIS A CE1  1 
ATOM   2821 N  NE2  . HIS A 1 182 ? -23.14832 -13.97361 -14.20299 1.000 10.10913 ? 1641 HIS A NE2  1 
ATOM   2822 H  H    . HIS A 1 182 ? -21.94545 -14.58866 -17.89125 1.000 12.15902 ? 1641 HIS A H    1 
ATOM   2823 H  HA   . HIS A 1 182 ? -23.49881 -13.35854 -19.57681 1.000 12.86963 ? 1641 HIS A HA   1 
ATOM   2824 H  HB2  . HIS A 1 182 ? -24.69491 -12.65045 -17.58250 1.000 12.36746 ? 1641 HIS A HB2  1 
ATOM   2825 H  HB3  . HIS A 1 182 ? -24.71408 -14.18306 -18.00222 1.000 12.36746 ? 1641 HIS A HB3  1 
ATOM   2826 H  HD2  . HIS A 1 182 ? -23.96580 -12.27590 -15.04187 1.000 11.96952 ? 1641 HIS A HD2  1 
ATOM   2827 H  HE1  . HIS A 1 182 ? -22.46376 -15.86068 -14.32242 1.000 11.26523 ? 1641 HIS A HE1  1 
ATOM   2828 H  HE2  . HIS A 1 182 ? -23.04619 -13.77340 -13.37288 1.000 12.13375 ? 1641 HIS A HE2  1 
ATOM   2829 N  N    . HIS A 1 183 ? -21.51510 -11.38757 -18.09967 1.000 9.80909  ? 1642 HIS A N    1 
ATOM   2830 C  CA   . HIS A 1 183 ? -21.06244 -9.99429  -18.09766 1.000 9.64854  ? 1642 HIS A CA   1 
ATOM   2831 C  C    . HIS A 1 183 ? -20.31167 -9.63255  -19.35472 1.000 9.95121  ? 1642 HIS A C    1 
ATOM   2832 O  O    . HIS A 1 183 ? -20.00654 -8.45211  -19.54505 1.000 11.21189 ? 1642 HIS A O    1 
ATOM   2833 C  CB   . HIS A 1 183 ? -20.29225 -9.73322  -16.80490 1.000 9.17217  ? 1642 HIS A CB   1 
ATOM   2834 C  CG   . HIS A 1 183 ? -21.16418 -9.84147  -15.60061 1.000 9.19849  ? 1642 HIS A CG   1 
ATOM   2835 N  ND1  . HIS A 1 183 ? -20.91580 -10.69981 -14.54787 1.000 9.55116  ? 1642 HIS A ND1  1 
ATOM   2836 C  CD2  . HIS A 1 183 ? -22.34737 -9.24008  -15.32802 1.000 10.36442 ? 1642 HIS A CD2  1 
ATOM   2837 C  CE1  . HIS A 1 183 ? -21.88181 -10.58048 -13.65696 1.000 10.30652 ? 1642 HIS A CE1  1 
ATOM   2838 N  NE2  . HIS A 1 183 ? -22.77023 -9.70739  -14.11573 1.000 10.37495 ? 1642 HIS A NE2  1 
ATOM   2839 H  H    . HIS A 1 183 ? -20.99381 -11.93728 -17.69264 1.000 11.77371 ? 1642 HIS A H    1 
ATOM   2840 H  HA   . HIS A 1 183 ? -21.80694 -9.37280  -18.07861 1.000 11.58105 ? 1642 HIS A HA   1 
ATOM   2841 H  HB2  . HIS A 1 183 ? -19.57898 -10.38537 -16.72219 1.000 11.00941 ? 1642 HIS A HB2  1 
ATOM   2842 H  HB3  . HIS A 1 183 ? -19.92129 -8.83733  -16.83089 1.000 11.00941 ? 1642 HIS A HB3  1 
ATOM   2843 H  HD2  . HIS A 1 183 ? -22.78951 -8.62374  -15.86611 1.000 12.44010 ? 1642 HIS A HD2  1 
ATOM   2844 H  HE1  . HIS A 1 183 ? -21.93176 -11.03159 -12.84523 1.000 12.37062 ? 1642 HIS A HE1  1 
ATOM   2845 H  HE2  . HIS A 1 183 ? -23.49441 -9.47381  -13.71497 1.000 12.45273 ? 1642 HIS A HE2  1 
ATOM   2846 N  N    . LEU A 1 184 ? -20.03081 -10.60605 -20.22158 1.000 9.77225  ? 1643 LEU A N    1 
ATOM   2847 C  CA   . LEU A 1 184 ? -19.44639 -10.36397 -21.53347 1.000 10.24599 ? 1643 LEU A CA   1 
ATOM   2848 C  C    . LEU A 1 184 ? -20.45354 -10.46053 -22.67390 1.000 11.49877 ? 1643 LEU A C    1 
ATOM   2849 O  O    . LEU A 1 184 ? -20.18411 -9.94299  -23.76042 1.000 12.02778 ? 1643 LEU A O    1 
ATOM   2850 C  CB   . LEU A 1 184 ? -18.34808 -11.39623 -21.80320 1.000 10.56445 ? 1643 LEU A CB   1 
ATOM   2851 C  CG   . LEU A 1 184 ? -17.12955 -11.28990 -20.90235 1.000 11.42244 ? 1643 LEU A CG   1 
ATOM   2852 C  CD1  . LEU A 1 184 ? -16.22559 -12.51311 -21.09395 1.000 12.54100 ? 1643 LEU A CD1  1 
ATOM   2853 C  CD2  . LEU A 1 184 ? -16.34802 -10.00791 -21.17422 1.000 12.10937 ? 1643 LEU A CD2  1 
ATOM   2854 H  H    . LEU A 1 184 ? -20.17505 -11.43940 -20.06559 1.000 11.72949 ? 1643 LEU A H    1 
ATOM   2855 H  HA   . LEU A 1 184 ? -19.06225 -9.47329  -21.53811 1.000 12.29798 ? 1643 LEU A HA   1 
ATOM   2856 H  HB2  . LEU A 1 184 ? -18.72400 -12.28206 -21.68119 1.000 12.68013 ? 1643 LEU A HB2  1 
ATOM   2857 H  HB3  . LEU A 1 184 ? -18.04425 -11.28788 -22.71800 1.000 12.68013 ? 1643 LEU A HB3  1 
ATOM   2858 H  HG   . LEU A 1 184 ? -17.42769 -11.26082 -19.97976 1.000 13.70973 ? 1643 LEU A HG   1 
ATOM   2859 H  HD11 . LEU A 1 184 ? -15.45312 -12.42898 -20.51334 1.000 15.05199 ? 1643 LEU A HD11 1 
ATOM   2860 H  HD12 . LEU A 1 184 ? -16.72461 -13.31327 -20.86671 1.000 15.05199 ? 1643 LEU A HD12 1 
ATOM   2861 H  HD13 . LEU A 1 184 ? -15.94040 -12.55304 -22.02022 1.000 15.05199 ? 1643 LEU A HD13 1 
ATOM   2862 H  HD21 . LEU A 1 184 ? -15.53219 -10.01813 -20.64960 1.000 14.53404 ? 1643 LEU A HD21 1 
ATOM   2863 H  HD22 . LEU A 1 184 ? -16.13316 -9.96340  -22.11908 1.000 14.53404 ? 1643 LEU A HD22 1 
ATOM   2864 H  HD23 . LEU A 1 184 ? -16.89345 -9.24621  -20.92279 1.000 14.53404 ? 1643 LEU A HD23 1 
ATOM   2865 N  N    . PHE A 1 185 ? -21.56830 -11.16838 -22.47641 1.000 11.51193 ? 1644 PHE A N    1 
ATOM   2866 C  CA   . PHE A 1 185 ? -22.46425 -11.51632 -23.56725 1.000 11.49351 ? 1644 PHE A CA   1 
ATOM   2867 C  C    . PHE A 1 185 ? -23.91312 -11.11071 -23.33861 1.000 12.11200 ? 1644 PHE A C    1 
ATOM   2868 O  O    . PHE A 1 185 ? -24.74520 -11.33906 -24.22798 1.000 13.39373 ? 1644 PHE A O    1 
ATOM   2869 C  CB   . PHE A 1 185 ? -22.39298 -13.03388 -23.84433 1.000 12.24622 ? 1644 PHE A CB   1 
ATOM   2870 C  CG   . PHE A 1 185 ? -21.05141 -13.49001 -24.34229 1.000 12.34887 ? 1644 PHE A CG   1 
ATOM   2871 C  CD1  . PHE A 1 185 ? -20.64082 -13.17695 -25.61586 1.000 13.06474 ? 1644 PHE A CD1  1 
ATOM   2872 C  CD2  . PHE A 1 185 ? -20.20503 -14.22437 -23.52501 1.000 11.90145 ? 1644 PHE A CD2  1 
ATOM   2873 C  CE1  . PHE A 1 185 ? -19.39898 -13.60046 -26.08466 1.000 13.35425 ? 1644 PHE A CE1  1 
ATOM   2874 C  CE2  . PHE A 1 185 ? -18.95853 -14.63059 -23.97799 1.000 12.34624 ? 1644 PHE A CE2  1 
ATOM   2875 C  CZ   . PHE A 1 185 ? -18.56844 -14.33253 -25.25244 1.000 12.31466 ? 1644 PHE A CZ   1 
ATOM   2876 H  H    . PHE A 1 185 ? -21.82563 -11.45940 -21.70915 1.000 13.81711 ? 1644 PHE A H    1 
ATOM   2877 H  HA   . PHE A 1 185 ? -22.16751 -11.04994 -24.36433 1.000 13.79500 ? 1644 PHE A HA   1 
ATOM   2878 H  HB2  . PHE A 1 185 ? -22.58244 -13.51130 -23.02149 1.000 14.69827 ? 1644 PHE A HB2  1 
ATOM   2879 H  HB3  . PHE A 1 185 ? -23.05268 -13.26004 -24.51853 1.000 14.69827 ? 1644 PHE A HB3  1 
ATOM   2880 H  HD1  . PHE A 1 185 ? -21.19682 -12.67797 -26.16974 1.000 15.68049 ? 1644 PHE A HD1  1 
ATOM   2881 H  HD2  . PHE A 1 185 ? -20.47625 -14.44689 -22.66372 1.000 14.28454 ? 1644 PHE A HD2  1 
ATOM   2882 H  HE1  . PHE A 1 185 ? -19.12964 -13.39304 -26.95030 1.000 16.02790 ? 1644 PHE A HE1  1 
ATOM   2883 H  HE2  . PHE A 1 185 ? -18.38983 -15.10475 -23.41527 1.000 14.81828 ? 1644 PHE A HE2  1 
ATOM   2884 H  HZ   . PHE A 1 185 ? -17.74117 -14.62251 -25.56296 1.000 14.78038 ? 1644 PHE A HZ   1 
ATOM   2885 N  N    . LEU A 1 186 ? -24.23600 -10.55293 -22.17534 1.000 11.82512 ? 1645 LEU A N    1 
ATOM   2886 C  CA   . LEU A 1 186 ? -25.54796 -9.98337  -21.88996 1.000 11.77248 ? 1645 LEU A CA   1 
ATOM   2887 C  C    . LEU A 1 186 ? -25.34364 -8.60299  -21.28924 1.000 12.02515 ? 1645 LEU A C    1 
ATOM   2888 O  O    . LEU A 1 186 ? -24.27662 -8.29107  -20.75951 1.000 12.25412 ? 1645 LEU A O    1 
ATOM   2889 C  CB   . LEU A 1 186 ? -26.32567 -10.85094 -20.89210 1.000 12.03304 ? 1645 LEU A CB   1 
ATOM   2890 C  CG   . LEU A 1 186 ? -26.73637 -12.24518 -21.38031 1.000 11.82512 ? 1645 LEU A CG   1 
ATOM   2891 C  CD1  . LEU A 1 186 ? -27.20890 -13.08215 -20.18628 1.000 12.39887 ? 1645 LEU A CD1  1 
ATOM   2892 C  CD2  . LEU A 1 186 ? -27.79011 -12.18616 -22.48217 1.000 12.95420 ? 1645 LEU A CD2  1 
ATOM   2893 H  H    . LEU A 1 186 ? -23.69199 -10.49052 -21.51219 1.000 14.19294 ? 1645 LEU A H    1 
ATOM   2894 H  HA   . LEU A 1 186 ? -26.06526 -9.91198  -22.70740 1.000 14.12978 ? 1645 LEU A HA   1 
ATOM   2895 H  HB2  . LEU A 1 186 ? -25.77198 -10.97507 -20.10538 1.000 14.44245 ? 1645 LEU A HB2  1 
ATOM   2896 H  HB3  . LEU A 1 186 ? -27.13962 -10.38010 -20.65400 1.000 14.44245 ? 1645 LEU A HB3  1 
ATOM   2897 H  HG   . LEU A 1 186 ? -25.96682 -12.67968 -21.78020 1.000 14.19295 ? 1645 LEU A HG   1 
ATOM   2898 H  HD11 . LEU A 1 186 ? -27.46849 -13.96233 -20.50058 1.000 14.88145 ? 1645 LEU A HD11 1 
ATOM   2899 H  HD12 . LEU A 1 186 ? -26.48272 -13.15975 -19.54789 1.000 14.88145 ? 1645 LEU A HD12 1 
ATOM   2900 H  HD13 . LEU A 1 186 ? -27.96755 -12.64168 -19.77235 1.000 14.88145 ? 1645 LEU A HD13 1 
ATOM   2901 H  HD21 . LEU A 1 186 ? -28.02104 -13.09027 -22.74704 1.000 15.54784 ? 1645 LEU A HD21 1 
ATOM   2902 H  HD22 . LEU A 1 186 ? -28.57612 -11.72978 -22.14334 1.000 15.54784 ? 1645 LEU A HD22 1 
ATOM   2903 H  HD23 . LEU A 1 186 ? -27.42748 -11.70179 -23.24032 1.000 15.54784 ? 1645 LEU A HD23 1 
ATOM   2904 N  N    . SER A 1 187 ? -26.38946 -7.78368  -21.34656 1.000 12.88841 ? 1646 SER A N    1 
ATOM   2905 C  CA   . SER A 1 187 ? -26.33147 -6.42966  -20.82312 1.000 13.49374 ? 1646 SER A CA   1 
ATOM   2906 C  C    . SER A 1 187 ? -27.74424 -5.97471  -20.48010 1.000 14.00696 ? 1646 SER A C    1 
ATOM   2907 O  O    . SER A 1 187 ? -28.71146 -6.73016  -20.60557 1.000 14.23594 ? 1646 SER A O    1 
ATOM   2908 C  CB   . SER A 1 187 ? -25.74375 -5.46064  -21.85605 1.000 14.23067 ? 1646 SER A CB   1 
ATOM   2909 O  OG   . SER A 1 187 ? -26.70525 -5.15518  -22.85889 1.000 15.47293 ? 1646 SER A OG   1 
ATOM   2910 H  H    . SER A 1 187 ? -27.15026 -7.99395  -21.68800 1.000 15.46888 ? 1646 SER A H    1 
ATOM   2911 H  HA   . SER A 1 187 ? -25.78305 -6.44654  -20.02321 1.000 16.19529 ? 1646 SER A HA   1 
ATOM   2912 H  HB2  . SER A 1 187 ? -25.48163 -4.64104  -21.40833 1.000 17.07961 ? 1646 SER A HB2  1 
ATOM   2913 H  HB3  . SER A 1 187 ? -24.97093 -5.87261  -22.27311 1.000 17.07961 ? 1646 SER A HB3  1 
ATOM   2914 H  HG   . SER A 1 187 ? -26.93256 -5.85620  -23.26200 1.000 18.57031 ? 1646 SER A HG   1 
ATOM   2915 N  N    . HIS A 1 188 ? -27.85678 -4.70645  -20.08463 1.000 14.52808 ? 1647 HIS A N    1 
ATOM   2916 C  CA   . HIS A 1 188 ? -29.16866 -4.10585  -19.86164 1.000 16.14669 ? 1647 HIS A CA   1 
ATOM   2917 C  C    . HIS A 1 188 ? -30.09686 -4.29246  -21.04276 1.000 17.27578 ? 1647 HIS A C    1 
ATOM   2918 O  O    . HIS A 1 188 ? -31.32375 -4.32494  -20.86476 1.000 18.29169 ? 1647 HIS A O    1 
ATOM   2919 C  CB   . HIS A 1 188 ? -29.02464 -2.60062  -19.64048 1.000 16.67570 ? 1647 HIS A CB   1 
ATOM   2920 C  CG   . HIS A 1 188 ? -28.34763 -2.25321  -18.36406 1.000 17.30473 ? 1647 HIS A CG   1 
ATOM   2921 N  ND1  . HIS A 1 188 ? -27.88106 -0.98641  -18.07835 1.000 17.09681 ? 1647 HIS A ND1  1 
ATOM   2922 C  CD2  . HIS A 1 188 ? -28.02051 -3.02453  -17.30346 1.000 17.75741 ? 1647 HIS A CD2  1 
ATOM   2923 C  CE1  . HIS A 1 188 ? -27.31391 -0.99228  -16.88508 1.000 17.69425 ? 1647 HIS A CE1  1 
ATOM   2924 N  NE2  . HIS A 1 188 ? -27.39348 -2.21397  -16.39033 1.000 18.13377 ? 1647 HIS A NE2  1 
ATOM   2925 H  H    . HIS A 1 188 ? -27.19463 -4.17716  -19.93971 1.000 17.43649 ? 1647 HIS A H    1 
ATOM   2926 H  HA   . HIS A 1 188 ? -29.54902 -4.53021  -19.07669 1.000 19.37883 ? 1647 HIS A HA   1 
ATOM   2927 H  HB2  . HIS A 1 188 ? -28.50134 -2.22610  -20.36629 1.000 20.01364 ? 1647 HIS A HB2  1 
ATOM   2928 H  HB3  . HIS A 1 188 ? -29.90798 -2.20008  -19.62730 1.000 20.01364 ? 1647 HIS A HB3  1 
ATOM   2929 H  HD1  . HIS A 1 188 ? -27.94867 -0.30206  -18.59477 1.000 20.51897 ? 1647 HIS A HD1  1 
ATOM   2930 H  HD2  . HIS A 1 188 ? -28.18882 -3.93437  -17.20987 1.000 21.31169 ? 1647 HIS A HD2  1 
ATOM   2931 H  HE1  . HIS A 1 188 ? -26.92450 -0.25981  -16.46466 1.000 21.23589 ? 1647 HIS A HE1  1 
ATOM   2932 N  N    . ASP A 1 189 ? -29.54632 -4.36117  -22.25708 1.000 17.83900 ? 1648 ASP A N    1 
ATOM   2933 C  CA   . ASP A 1 189 ? -30.36277 -4.52009  -23.45593 1.000 19.09178 ? 1648 ASP A CA   1 
ATOM   2934 C  C    . ASP A 1 189 ? -31.16021 -5.81686  -23.44701 1.000 17.76268 ? 1648 ASP A C    1 
ATOM   2935 O  O    . ASP A 1 189 ? -32.13745 -5.94067  -24.19576 1.000 18.77332 ? 1648 ASP A O    1 
ATOM   2936 C  CB   . ASP A 1 189 ? -29.50688 -4.48397  -24.72600 1.000 22.07635 ? 1648 ASP A CB   1 
ATOM   2937 C  CG   . ASP A 1 189 ? -28.90278 -3.11600  -24.98571 1.000 25.78206 ? 1648 ASP A CG   1 
ATOM   2938 O  OD1  . ASP A 1 189 ? -29.35301 -2.13248  -24.39237 1.000 28.06917 ? 1648 ASP A OD1  1 
ATOM   2939 O  OD2  . ASP A 1 189 ? -27.98356 -3.02454  -25.82869 1.000 27.05326 ? 1648 ASP A OD2  1 
ATOM   2940 H  H    . ASP A 1 189 ? -28.70151 -4.31807  -22.41209 1.000 21.40960 ? 1648 ASP A H    1 
ATOM   2941 H  HA   . ASP A 1 189 ? -30.97545 -3.76863  -23.48476 1.000 22.91294 ? 1648 ASP A HA   1 
ATOM   2942 H  HB2  . ASP A 1 189 ? -28.78073 -5.12082  -24.63643 1.000 26.49442 ? 1648 ASP A HB2  1 
ATOM   2943 H  HB3  . ASP A 1 189 ? -30.06065 -4.71717  -25.48748 1.000 26.49442 ? 1648 ASP A HB3  1 
ATOM   2944 N  N    . ASP A 1 190 ? -30.76344 -6.78874  -22.63407 1.000 16.51253 ? 1649 ASP A N    1 
ATOM   2945 C  CA   . ASP A 1 190 ? -31.43522 -8.08064  -22.57156 1.000 16.39672 ? 1649 ASP A CA   1 
ATOM   2946 C  C    . ASP A 1 190 ? -32.48796 -8.16355  -21.47900 1.000 15.48609 ? 1649 ASP A C    1 
ATOM   2947 O  O    . ASP A 1 190 ? -33.21225 -9.16250  -21.40947 1.000 15.75980 ? 1649 ASP A O    1 
ATOM   2948 C  CB   . ASP A 1 190 ? -30.38364 -9.18072  -22.39886 1.000 16.68623 ? 1649 ASP A CB   1 
ATOM   2949 C  CG   . ASP A 1 190 ? -29.39783 -9.18046  -23.52997 1.000 18.26537 ? 1649 ASP A CG   1 
ATOM   2950 O  OD1  . ASP A 1 190 ? -29.81643 -9.54908  -24.64381 1.000 20.85252 ? 1649 ASP A OD1  1 
ATOM   2951 O  OD2  . ASP A 1 190 ? -28.22769 -8.79974  -23.34340 1.000 17.39948 ? 1649 ASP A OD2  1 
ATOM   2952 H  H    . ASP A 1 190 ? -30.09410 -6.72268  -22.09815 1.000 19.81783 ? 1649 ASP A H    1 
ATOM   2953 H  HA   . ASP A 1 190 ? -31.90203 -8.24086  -23.40661 1.000 19.67886 ? 1649 ASP A HA   1 
ATOM   2954 H  HB2  . ASP A 1 190 ? -29.89905 -9.03456  -21.57139 1.000 20.02628 ? 1649 ASP A HB2  1 
ATOM   2955 H  HB3  . ASP A 1 190 ? -30.82364 -10.04492 -22.37743 1.000 20.02628 ? 1649 ASP A HB3  1 
ATOM   2956 N  N    . LEU A 1 191 ? -32.63173 -7.12792  -20.65379 1.000 15.74401 ? 1650 LEU A N    1 
ATOM   2957 C  CA   . LEU A 1 191 ? -33.54134 -7.23260  -19.51766 1.000 15.96509 ? 1650 LEU A CA   1 
ATOM   2958 C  C    . LEU A 1 191 ? -35.00683 -7.29043  -19.93919 1.000 17.07838 ? 1650 LEU A C    1 
ATOM   2959 O  O    . LEU A 1 191 ? -35.81265 -7.94472  -19.26349 1.000 17.78110 ? 1650 LEU A O    1 
ATOM   2960 C  CB   . LEU A 1 191 ? -33.28920 -6.10568  -18.51330 1.000 16.48621 ? 1650 LEU A CB   1 
ATOM   2961 C  CG   . LEU A 1 191 ? -31.99173 -6.26123  -17.71241 1.000 18.43118 ? 1650 LEU A CG   1 
ATOM   2962 C  CD1  . LEU A 1 191 ? -31.69683 -5.00416  -16.91703 1.000 19.14442 ? 1650 LEU A CD1  1 
ATOM   2963 C  CD2  . LEU A 1 191 ? -32.03972 -7.45035  -16.78458 1.000 19.24180 ? 1650 LEU A CD2  1 
ATOM   2964 H  H    . LEU A 1 191 ? -32.22505 -6.37376  -20.72767 1.000 18.89561 ? 1650 LEU A H    1 
ATOM   2965 H  HA   . LEU A 1 191 ? -33.35214 -8.06666  -19.06001 1.000 19.16091 ? 1650 LEU A HA   1 
ATOM   2966 H  HB2  . LEU A 1 191 ? -33.23970 -5.26568  -18.99585 1.000 19.78625 ? 1650 LEU A HB2  1 
ATOM   2967 H  HB3  . LEU A 1 191 ? -34.02523 -6.08270  -17.88193 1.000 19.78625 ? 1650 LEU A HB3  1 
ATOM   2968 H  HG   . LEU A 1 191 ? -31.27322 -6.41006  -18.34683 1.000 22.12021 ? 1650 LEU A HG   1 
ATOM   2969 H  HD11 . LEU A 1 191 ? -30.86213 -5.12254  -16.43728 1.000 22.97610 ? 1650 LEU A HD11 1 
ATOM   2970 H  HD12 . LEU A 1 191 ? -31.62390 -4.25396  -17.52759 1.000 22.97610 ? 1650 LEU A HD12 1 
ATOM   2971 H  HD13 . LEU A 1 191 ? -32.42024 -4.85065  -16.28932 1.000 22.97610 ? 1650 LEU A HD13 1 
ATOM   2972 H  HD21 . LEU A 1 191 ? -31.28685 -7.40554  -16.17459 1.000 23.09296 ? 1650 LEU A HD21 1 
ATOM   2973 H  HD22 . LEU A 1 191 ? -32.87135 -7.42835  -16.28577 1.000 23.09296 ? 1650 LEU A HD22 1 
ATOM   2974 H  HD23 . LEU A 1 191 ? -31.99108 -8.26372  -17.31086 1.000 23.09296 ? 1650 LEU A HD23 1 
ATOM   2975 N  N    . GLU A 1 192 ? -35.37136 -6.61984  -21.03286 1.000 18.37064 ? 1651 GLU A N    1 
ATOM   2976 C  CA   . GLU A 1 192 ? -36.76115 -6.69225  -21.48895 1.000 20.06295 ? 1651 GLU A CA   1 
ATOM   2977 C  C    . GLU A 1 192 ? -37.13434 -8.12060  -21.86599 1.000 18.50224 ? 1651 GLU A C    1 
ATOM   2978 O  O    . GLU A 1 192 ? -38.20426 -8.61701  -21.48271 1.000 18.84438 ? 1651 GLU A O    1 
ATOM   2979 C  CB   . GLU A 1 192 ? -36.97966 -5.73878  -22.66479 1.000 24.05027 ? 1651 GLU A CB   1 
ATOM   2980 C  CG   . GLU A 1 192 ? -38.38334 -5.84762  -23.26842 1.000 28.90875 ? 1651 GLU A CG   1 
ATOM   2981 C  CD   . GLU A 1 192 ? -38.66071 -4.80623  -24.33901 1.000 33.56457 ? 1651 GLU A CD   1 
ATOM   2982 O  OE1  . GLU A 1 192 ? -37.72059 -4.40979  -25.06478 1.000 35.48059 ? 1651 GLU A OE1  1 
ATOM   2983 O  OE2  . GLU A 1 192 ? -39.82789 -4.38631  -24.45684 1.000 35.13844 ? 1651 GLU A OE2  1 
ATOM   2984 H  H    . GLU A 1 192 ? -34.85195 -6.13155  -21.51389 1.000 22.04757 ? 1651 GLU A H    1 
ATOM   2985 H  HA   . GLU A 1 192 ? -37.34774 -6.40895  -20.77023 1.000 24.07834 ? 1651 GLU A HA   1 
ATOM   2986 H  HB2  . GLU A 1 192 ? -36.85514 -4.82695  -22.35829 1.000 28.86312 ? 1651 GLU A HB2  1 
ATOM   2987 H  HB3  . GLU A 1 192 ? -36.33705 -5.94530  -23.36142 1.000 28.86312 ? 1651 GLU A HB3  1 
ATOM   2988 H  HG2  . GLU A 1 192 ? -38.48413 -6.72368  -23.67247 1.000 34.69330 ? 1651 GLU A HG2  1 
ATOM   2989 H  HG3  . GLU A 1 192 ? -39.03839 -5.73041  -22.56268 1.000 34.69330 ? 1651 GLU A HG3  1 
ATOM   2990 N  N    . ARG A 1 193 ? -36.25399 -8.80785  -22.59467 1.000 17.39158 ? 1652 ARG A N    1 
ATOM   2991 C  CA   . ARG A 1 193 ? -36.52006 -10.19201 -22.97341 1.000 17.53107 ? 1652 ARG A CA   1 
ATOM   2992 C  C    . ARG A 1 193 ? -36.54165 -11.09957 -21.75318 1.000 17.08628 ? 1652 ARG A C    1 
ATOM   2993 O  O    . ARG A 1 193 ? -37.42828 -11.94818 -21.61187 1.000 17.93901 ? 1652 ARG A O    1 
ATOM   2994 C  CB   . ARG A 1 193 ? -35.46081 -10.66656 -23.97159 1.000 18.50224 ? 1652 ARG A CB   1 
ATOM   2995 C  CG   . ARG A 1 193 ? -35.49655 -12.16869 -24.25534 1.000 19.34708 ? 1652 ARG A CG   1 
ATOM   2996 C  CD   . ARG A 1 193 ? -34.44514 -12.57628 -25.29152 1.000 19.61290 ? 1652 ARG A CD   1 
ATOM   2997 N  NE   . ARG A 1 193 ? -33.08403 -12.35082 -24.80799 1.000 19.17864 ? 1652 ARG A NE   1 
ATOM   2998 C  CZ   . ARG A 1 193 ? -32.41057 -13.17058 -24.00956 1.000 19.93662 ? 1652 ARG A CZ   1 
ATOM   2999 N  NH1  . ARG A 1 193 ? -32.92319 -14.31723 -23.59200 1.000 21.00780 ? 1652 ARG A NH1  1 
ATOM   3000 N  NH2  . ARG A 1 193 ? -31.18900 -12.82766 -23.61173 1.000 19.58921 ? 1652 ARG A NH2  1 
ATOM   3001 H  H    . ARG A 1 193 ? -35.50361 -8.49845  -22.87893 1.000 20.87269 ? 1652 ARG A H    1 
ATOM   3002 H  HA   . ARG A 1 193 ? -37.38955 -10.23943 -23.40077 1.000 21.04008 ? 1652 ARG A HA   1 
ATOM   3003 H  HB2  . ARG A 1 193 ? -35.59868 -10.20459 -24.81330 1.000 22.20548 ? 1652 ARG A HB2  1 
ATOM   3004 H  HB3  . ARG A 1 193 ? -34.58322 -10.45477 -23.61677 1.000 22.20548 ? 1652 ARG A HB3  1 
ATOM   3005 H  HG2  . ARG A 1 193 ? -35.31818 -12.65397 -23.43462 1.000 23.21929 ? 1652 ARG A HG2  1 
ATOM   3006 H  HG3  . ARG A 1 193 ? -36.37109 -12.40889 -24.59940 1.000 23.21929 ? 1652 ARG A HG3  1 
ATOM   3007 H  HD2  . ARG A 1 193 ? -34.54319 -13.52037 -25.49147 1.000 23.53827 ? 1652 ARG A HD2  1 
ATOM   3008 H  HD3  . ARG A 1 193 ? -34.57115 -12.05162 -26.09759 1.000 23.53827 ? 1652 ARG A HD3  1 
ATOM   3009 H  HE   . ARG A 1 193 ? -32.68826 -11.63031 -25.06064 1.000 23.01716 ? 1652 ARG A HE   1 
ATOM   3010 H  HH11 . ARG A 1 193 ? -33.71395 -14.54952 -23.83762 1.000 25.21216 ? 1652 ARG A HH11 1 
ATOM   3011 H  HH12 . ARG A 1 193 ? -32.46549 -14.82997 -23.07507 1.000 25.21216 ? 1652 ARG A HH12 1 
ATOM   3012 H  HH21 . ARG A 1 193 ? -30.84523 -12.08342 -23.87160 1.000 23.50985 ? 1652 ARG A HH21 1 
ATOM   3013 H  HH22 . ARG A 1 193 ? -30.74270 -13.35010 -23.09456 1.000 23.50985 ? 1652 ARG A HH22 1 
ATOM   3014 N  N    . LEU A 1 194 ? -35.53121 -10.97498 -20.88854 1.000 16.85730 ? 1653 LEU A N    1 
ATOM   3015 C  CA   . LEU A 1 194 ? -35.43153 -11.86598 -19.74216 1.000 16.84941 ? 1653 LEU A CA   1 
ATOM   3016 C  C    . LEU A 1 194 ? -36.57023 -11.64509 -18.75973 1.000 16.88889 ? 1653 LEU A C    1 
ATOM   3017 O  O    . LEU A 1 194 ? -37.04862 -12.60120 -18.14491 1.000 17.66793 ? 1653 LEU A O    1 
ATOM   3018 C  CB   . LEU A 1 194 ? -34.10080 -11.64435 -19.03798 1.000 17.32841 ? 1653 LEU A CB   1 
ATOM   3019 C  CG   . LEU A 1 194 ? -32.87307 -12.11906 -19.80697 1.000 17.39684 ? 1653 LEU A CG   1 
ATOM   3020 C  CD1  . LEU A 1 194 ? -31.61433 -11.62008 -19.12331 1.000 17.27578 ? 1653 LEU A CD1  1 
ATOM   3021 C  CD2  . LEU A 1 194 ? -32.87028 -13.63443 -19.93040 1.000 17.61003 ? 1653 LEU A CD2  1 
ATOM   3022 H  H    . LEU A 1 194 ? -34.90247 -10.39098 -20.94545 1.000 20.23156 ? 1653 LEU A H    1 
ATOM   3023 H  HA   . LEU A 1 194 ? -35.47620 -12.78154 -20.05943 1.000 20.22209 ? 1653 LEU A HA   1 
ATOM   3024 H  HB2  . LEU A 1 194 ? -33.99415 -10.69354 -18.87834 1.000 20.79689 ? 1653 LEU A HB2  1 
ATOM   3025 H  HB3  . LEU A 1 194 ? -34.11817 -12.12253 -18.19421 1.000 20.79689 ? 1653 LEU A HB3  1 
ATOM   3026 H  HG   . LEU A 1 194 ? -32.89162 -11.75753 -20.70689 1.000 20.87901 ? 1653 LEU A HG   1 
ATOM   3027 H  HD11 . LEU A 1 194 ? -30.84110 -11.92835 -19.62129 1.000 20.73373 ? 1653 LEU A HD11 1 
ATOM   3028 H  HD12 . LEU A 1 194 ? -31.62939 -10.65042 -19.10264 1.000 20.73373 ? 1653 LEU A HD12 1 
ATOM   3029 H  HD13 . LEU A 1 194 ? -31.58631 -11.96981 -18.21898 1.000 20.73373 ? 1653 LEU A HD13 1 
ATOM   3030 H  HD21 . LEU A 1 194 ? -32.01551 -13.92052 -20.28875 1.000 21.13483 ? 1653 LEU A HD21 1 
ATOM   3031 H  HD22 . LEU A 1 194 ? -33.00760 -14.02305 -19.05233 1.000 21.13483 ? 1653 LEU A HD22 1 
ATOM   3032 H  HD23 . LEU A 1 194 ? -33.58600 -13.90400 -20.52704 1.000 21.13483 ? 1653 LEU A HD23 1 
ATOM   3033 N  N    . GLY A 1 195 ? -37.00374 -10.39643 -18.59411 1.000 16.37830 ? 1654 GLY A N    1 
ATOM   3034 C  CA   . GLY A 1 195 ? -37.88850 -10.02683 -17.51147 1.000 16.40199 ? 1654 GLY A CA   1 
ATOM   3035 C  C    . GLY A 1 195 ? -37.18273 -9.89262  -16.17848 1.000 16.20723 ? 1654 GLY A C    1 
ATOM   3036 O  O    . GLY A 1 195 ? -36.01206 -10.24734 -16.01645 1.000 16.35988 ? 1654 GLY A O    1 
ATOM   3037 H  H    . GLY A 1 195 ? -36.79186 -9.74014  -19.10791 1.000 19.65676 ? 1654 GLY A H    1 
ATOM   3038 H  HA2  . GLY A 1 195 ? -38.30542 -9.17590  -17.71883 1.000 19.68518 ? 1654 GLY A HA2  1 
ATOM   3039 H  HA3  . GLY A 1 195 ? -38.57833 -10.70268 -17.42063 1.000 19.68518 ? 1654 GLY A HA3  1 
ATOM   3040 N  N    . PRO A 1 196 ? -37.89266 -9.35026  -15.18742 1.000 16.19407 ? 1655 PRO A N    1 
ATOM   3041 C  CA   . PRO A 1 196 ? -37.22504 -8.96870  -13.93532 1.000 16.68886 ? 1655 PRO A CA   1 
ATOM   3042 C  C    . PRO A 1 196 ? -36.87958 -10.13381 -13.02817 1.000 16.55201 ? 1655 PRO A C    1 
ATOM   3043 O  O    . PRO A 1 196 ? -35.99651 -9.98830  -12.16960 1.000 19.12073 ? 1655 PRO A O    1 
ATOM   3044 C  CB   . PRO A 1 196 ? -38.23678 -8.02346  -13.27700 1.000 17.99954 ? 1655 PRO A CB   1 
ATOM   3045 C  CG   . PRO A 1 196 ? -39.54865 -8.48401  -13.82720 1.000 18.01797 ? 1655 PRO A CG   1 
ATOM   3046 C  CD   . PRO A 1 196 ? -39.31320 -8.94749  -15.22069 1.000 17.04154 ? 1655 PRO A CD   1 
ATOM   3047 H  HA   . PRO A 1 196 ? -36.41112 -8.47773  -14.12862 1.000 20.02943 ? 1655 PRO A HA   1 
ATOM   3048 H  HB2  . PRO A 1 196 ? -38.20632 -8.11676  -12.31197 1.000 21.60225 ? 1655 PRO A HB2  1 
ATOM   3049 H  HB3  . PRO A 1 196 ? -38.05179 -7.10481  -13.52749 1.000 21.60225 ? 1655 PRO A HB3  1 
ATOM   3050 H  HG2  . PRO A 1 196 ? -39.88653 -9.21190  -13.28230 1.000 21.62436 ? 1655 PRO A HG2  1 
ATOM   3051 H  HG3  . PRO A 1 196 ? -40.17642 -7.74459  -13.81930 1.000 21.62436 ? 1655 PRO A HG3  1 
ATOM   3052 H  HD2  . PRO A 1 196 ? -39.88390 -9.70106  -15.43825 1.000 20.45264 ? 1655 PRO A HD2  1 
ATOM   3053 H  HD3  . PRO A 1 196 ? -39.45659 -8.22849  -15.85582 1.000 20.45264 ? 1655 PRO A HD3  1 
ATOM   3054 N  N    . GLY A 1 197 ? -37.51797 -11.28347 -13.19180 1.000 15.00708 ? 1656 GLY A N    1 
ATOM   3055 C  CA   . GLY A 1 197 ? -37.18929 -12.42906 -12.36841 1.000 14.90181 ? 1656 GLY A CA   1 
ATOM   3056 C  C    . GLY A 1 197 ? -35.99678 -13.18506 -12.92384 1.000 14.51755 ? 1656 GLY A C    1 
ATOM   3057 O  O    . GLY A 1 197 ? -34.98177 -13.34888 -12.23865 1.000 14.51229 ? 1656 GLY A O    1 
ATOM   3058 H  H    . GLY A 1 197 ? -38.14021 -11.42196 -13.76906 1.000 18.01130 ? 1656 GLY A H    1 
ATOM   3059 H  HA2  . GLY A 1 197 ? -36.97746 -12.13284 -11.46937 1.000 17.88496 ? 1656 GLY A HA2  1 
ATOM   3060 H  HA3  . GLY A 1 197 ? -37.94875 -13.03135 -12.33175 1.000 17.88496 ? 1656 GLY A HA3  1 
ATOM   3061 N  N    . LYS A 1 198 ? -36.11719 -13.63751 -14.17278 1.000 14.46228 ? 1657 LYS A N    1 
ATOM   3062 C  CA   . LYS A 1 198 ? -34.99659 -14.30047 -14.82222 1.000 15.39134 ? 1657 LYS A CA   1 
ATOM   3063 C  C    . LYS A 1 198 ? -33.76487 -13.40531 -14.81782 1.000 15.96246 ? 1657 LYS A C    1 
ATOM   3064 O  O    . LYS A 1 198 ? -32.63683 -13.88224 -14.68081 1.000 16.49147 ? 1657 LYS A O    1 
ATOM   3065 C  CB   . LYS A 1 198 ? -35.33514 -14.64846 -16.26367 1.000 16.47305 ? 1657 LYS A CB   1 
ATOM   3066 C  CG   . LYS A 1 198 ? -36.16803 -15.85768 -16.50334 1.000 18.52066 ? 1657 LYS A CG   1 
ATOM   3067 C  CD   . LYS A 1 198 ? -36.32984 -15.93115 -18.03305 1.000 20.59722 ? 1657 LYS A CD   1 
ATOM   3068 C  CE   . LYS A 1 198 ? -36.79021 -17.23052 -18.52401 1.000 20.68144 ? 1657 LYS A CE   1 
ATOM   3069 N  NZ   . LYS A 1 198 ? -37.12432 -17.09178 -19.95005 1.000 19.09442 ? 1657 LYS A NZ   1 
ATOM   3070 H  H    . LYS A 1 198 ? -36.82618 -13.57281 -14.65523 1.000 17.35753 ? 1657 LYS A H    1 
ATOM   3071 H  HA   . LYS A 1 198 ? -34.81361 -15.12061 -14.33767 1.000 18.47241 ? 1657 LYS A HA   1 
ATOM   3072 H  HB2  . LYS A 1 198 ? -35.81624 -13.89751 -16.64514 1.000 19.77046 ? 1657 LYS A HB2  1 
ATOM   3073 H  HB3  . LYS A 1 198 ? -34.50111 -14.78457 -16.73987 1.000 19.77046 ? 1657 LYS A HB3  1 
ATOM   3074 H  HG2  . LYS A 1 198 ? -35.72175 -16.65513 -16.17808 1.000 22.22759 ? 1657 LYS A HG2  1 
ATOM   3075 H  HG3  . LYS A 1 198 ? -37.03695 -15.76838 -16.08155 1.000 22.22759 ? 1657 LYS A HG3  1 
ATOM   3076 H  HD2  . LYS A 1 198 ? -36.97923 -15.26581 -18.30966 1.000 24.71946 ? 1657 LYS A HD2  1 
ATOM   3077 H  HD3  . LYS A 1 198 ? -35.47132 -15.74856 -18.44597 1.000 24.71946 ? 1657 LYS A HD3  1 
ATOM   3078 H  HE2  . LYS A 1 198 ? -36.08828 -17.89250 -18.42415 1.000 24.82053 ? 1657 LYS A HE2  1 
ATOM   3079 H  HE3  . LYS A 1 198 ? -37.58130 -17.50977 -18.03710 1.000 24.82053 ? 1657 LYS A HE3  1 
ATOM   3080 H  HZ1  . LYS A 1 198 ? -36.40784 -16.82571 -20.40607 1.000 22.91610 ? 1657 LYS A HZ1  1 
ATOM   3081 H  HZ2  . LYS A 1 198 ? -37.40015 -17.87289 -20.27545 1.000 22.91610 ? 1657 LYS A HZ2  1 
ATOM   3082 H  HZ3  . LYS A 1 198 ? -37.77237 -16.49063 -20.05376 1.000 22.91610 ? 1657 LYS A HZ3  1 
ATOM   3083 N  N    . GLY A 1 199 ? -33.95734 -12.10280 -14.99165 1.000 15.75191 ? 1658 GLY A N    1 
ATOM   3084 C  CA   . GLY A 1 199 ? -32.82847 -11.19483 -15.07834 1.000 15.71769 ? 1658 GLY A CA   1 
ATOM   3085 C  C    . GLY A 1 199 ? -32.10072 -10.94551 -13.77137 1.000 15.37028 ? 1658 GLY A C    1 
ATOM   3086 O  O    . GLY A 1 199 ? -31.03916 -10.31110 -13.79466 1.000 16.20196 ? 1658 GLY A O    1 
ATOM   3087 H  H    . GLY A 1 199 ? -34.72695 -11.72542 -15.06151 1.000 18.90509 ? 1658 GLY A H    1 
ATOM   3088 H  HA2  . GLY A 1 199 ? -32.18650 -11.55816 -15.70823 1.000 18.86403 ? 1658 GLY A HA2  1 
ATOM   3089 H  HA3  . GLY A 1 199 ? -33.14419 -10.33877 -15.40757 1.000 18.86403 ? 1658 GLY A HA3  1 
ATOM   3090 N  N    . GLU A 1 200 ? -32.62648 -11.41733 -12.64550 1.000 14.80969 ? 1659 GLU A N    1 
ATOM   3091 C  CA   . GLU A 1 200 ? -31.97135 -11.20143 -11.35985 1.000 15.92035 ? 1659 GLU A CA   1 
ATOM   3092 C  C    . GLU A 1 200 ? -30.65509 -11.98089 -11.28310 1.000 13.77273 ? 1659 GLU A C    1 
ATOM   3093 O  O    . GLU A 1 200 ? -30.64534 -13.21826 -11.39341 1.000 13.37531 ? 1659 GLU A O    1 
ATOM   3094 C  CB   . GLU A 1 200 ? -32.88828 -11.64104 -10.22132 1.000 19.89714 ? 1659 GLU A CB   1 
ATOM   3095 C  CG   . GLU A 1 200 ? -33.94947 -10.64378 -9.76578  1.000 25.55308 ? 1659 GLU A CG   1 
ATOM   3096 C  CD   . GLU A 1 200 ? -33.35827 -9.40822  -9.09705  1.000 30.73265 ? 1659 GLU A CD   1 
ATOM   3097 O  OE1  . GLU A 1 200 ? -32.42626 -9.52704  -8.27232  1.000 32.48812 ? 1659 GLU A OE1  1 
ATOM   3098 O  OE2  . GLU A 1 200 ? -33.86008 -8.30968  -9.39190  1.000 32.76710 ? 1659 GLU A OE2  1 
ATOM   3099 H  H    . GLU A 1 200 ? -33.35962 -11.86446 -12.59884 1.000 17.77443 ? 1659 GLU A H    1 
ATOM   3100 H  HA   . GLU A 1 200 ? -31.77776 -10.25510 -11.27110 1.000 19.10722 ? 1659 GLU A HA   1 
ATOM   3101 H  HB2  . GLU A 1 200 ? -33.35629 -12.44166 -10.50570 1.000 23.87937 ? 1659 GLU A HB2  1 
ATOM   3102 H  HB3  . GLU A 1 200 ? -32.33457 -11.83697 -9.44936  1.000 23.87937 ? 1659 GLU A HB3  1 
ATOM   3103 H  HG2  . GLU A 1 200 ? -34.45871 -10.35098 -10.53768 1.000 30.66650 ? 1659 GLU A HG2  1 
ATOM   3104 H  HG3  . GLU A 1 200 ? -34.53596 -11.07776 -9.12657  1.000 30.66650 ? 1659 GLU A HG3  1 
ATOM   3105 N  N    . VAL A 1 201 ? -29.55344 -11.26151 -11.07649 1.000 13.21213 ? 1660 VAL A N    1 
ATOM   3106 C  CA   . VAL A 1 201 ? -28.22912 -11.86880 -10.93576 1.000 12.30413 ? 1660 VAL A CA   1 
ATOM   3107 C  C    . VAL A 1 201 ? -27.37426 -10.89377 -10.13105 1.000 11.85407 ? 1660 VAL A C    1 
ATOM   3108 O  O    . VAL A 1 201 ? -27.61047 -9.68608  -10.14655 1.000 12.18569 ? 1660 VAL A O    1 
ATOM   3109 C  CB   . VAL A 1 201 ? -27.61433 -12.20254 -12.32318 1.000 12.65154 ? 1660 VAL A CB   1 
ATOM   3110 C  CG1  . VAL A 1 201 ? -27.45112 -10.96308 -13.18564 1.000 13.21739 ? 1660 VAL A CG1  1 
ATOM   3111 C  CG2  . VAL A 1 201 ? -26.27629 -12.96157 -12.17699 1.000 13.23055 ? 1660 VAL A CG2  1 
ATOM   3112 H  H    . VAL A 1 201 ? -29.54543 -10.40392 -11.01266 1.000 15.85735 ? 1660 VAL A H    1 
ATOM   3113 H  HA   . VAL A 1 201 ? -28.29324 -12.70008 -10.44001 1.000 14.76775 ? 1660 VAL A HA   1 
ATOM   3114 H  HB   . VAL A 1 201 ? -28.23606 -12.78768 -12.78356 1.000 15.18464 ? 1660 VAL A HB   1 
ATOM   3115 H  HG11 . VAL A 1 201 ? -27.18301 -11.23242 -14.07810 1.000 15.86367 ? 1660 VAL A HG11 1 
ATOM   3116 H  HG12 . VAL A 1 201 ? -28.29747 -10.49064 -13.22296 1.000 15.86367 ? 1660 VAL A HG12 1 
ATOM   3117 H  HG13 . VAL A 1 201 ? -26.77108 -10.39303 -12.79386 1.000 15.86367 ? 1660 VAL A HG13 1 
ATOM   3118 H  HG21 . VAL A 1 201 ? -25.96246 -13.22082 -13.05745 1.000 15.87946 ? 1660 VAL A HG21 1 
ATOM   3119 H  HG22 . VAL A 1 201 ? -25.62726 -12.37868 -11.75286 1.000 15.87946 ? 1660 VAL A HG22 1 
ATOM   3120 H  HG23 . VAL A 1 201 ? -26.41881 -13.75058 -11.63105 1.000 15.87946 ? 1660 VAL A HG23 1 
ATOM   3121 N  N    . ARG A 1 202 ? -26.39884 -11.43069 -9.40481  1.000 11.28032 ? 1661 ARG A N    1 
ATOM   3122 C  CA   . ARG A 1 202 ? -25.45396 -10.60802 -8.66817  1.000 11.61457 ? 1661 ARG A CA   1 
ATOM   3123 C  C    . ARG A 1 202 ? -24.05061 -11.07889 -9.02510  1.000 11.89882 ? 1661 ARG A C    1 
ATOM   3124 O  O    . ARG A 1 202 ? -23.73811 -12.26420 -8.89282  1.000 13.24897 ? 1661 ARG A O    1 
ATOM   3125 C  CB   . ARG A 1 202 ? -25.63400 -10.73575 -7.14547  1.000 13.03843 ? 1661 ARG A CB   1 
ATOM   3126 C  CG   . ARG A 1 202 ? -26.98914 -10.28172 -6.64888  1.000 15.89930 ? 1661 ARG A CG   1 
ATOM   3127 C  CD   . ARG A 1 202 ? -27.17749 -8.79212  -6.79974  1.000 19.34971 ? 1661 ARG A CD   1 
ATOM   3128 N  NE   . ARG A 1 202 ? -28.49080 -8.41020  -6.29983  1.000 21.62893 ? 1661 ARG A NE   1 
ATOM   3129 C  CZ   . ARG A 1 202 ? -29.64790 -8.79503  -6.83118  1.000 23.47125 ? 1661 ARG A CZ   1 
ATOM   3130 N  NH1  . ARG A 1 202 ? -29.71391 -9.33448  -8.03249  1.000 23.78182 ? 1661 ARG A NH1  1 
ATOM   3131 N  NH2  . ARG A 1 202 ? -30.76861 -8.61984  -6.14269  1.000 24.63981 ? 1661 ARG A NH2  1 
ATOM   3132 H  H    . ARG A 1 202 ? -26.26514 -12.27641 -9.32432  1.000 13.53918 ? 1661 ARG A H    1 
ATOM   3133 H  HA   . ARG A 1 202 ? -25.58938 -9.68101  -8.91957  1.000 13.94028 ? 1661 ARG A HA   1 
ATOM   3134 H  HB2  . ARG A 1 202 ? -25.52441 -11.66669 -6.89601  1.000 15.64891 ? 1661 ARG A HB2  1 
ATOM   3135 H  HB3  . ARG A 1 202 ? -24.96095 -10.19301 -6.70577  1.000 15.64891 ? 1661 ARG A HB3  1 
ATOM   3136 H  HG2  . ARG A 1 202 ? -27.68237 -10.72769 -7.16019  1.000 19.08195 ? 1661 ARG A HG2  1 
ATOM   3137 H  HG3  . ARG A 1 202 ? -27.07548 -10.50394 -5.70863  1.000 19.08195 ? 1661 ARG A HG3  1 
ATOM   3138 H  HD2  . ARG A 1 202 ? -26.49982 -8.32249  -6.28876  1.000 23.22245 ? 1661 ARG A HD2  1 
ATOM   3139 H  HD3  . ARG A 1 202 ? -27.11609 -8.54700  -7.73624  1.000 23.22245 ? 1661 ARG A HD3  1 
ATOM   3140 H  HE   . ARG A 1 202 ? -28.52050 -7.89778  -5.60980  1.000 25.95751 ? 1661 ARG A HE   1 
ATOM   3141 H  HH11 . ARG A 1 202 ? -28.99678 -9.44547  -8.49401  1.000 28.54098 ? 1661 ARG A HH11 1 
ATOM   3142 H  HH12 . ARG A 1 202 ? -30.47410 -9.57534  -8.35451  1.000 28.54098 ? 1661 ARG A HH12 1 
ATOM   3143 H  HH21 . ARG A 1 202 ? -30.74180 -8.26085  -5.36166  1.000 29.57057 ? 1661 ARG A HH21 1 
ATOM   3144 H  HH22 . ARG A 1 202 ? -31.52178 -8.86530  -6.47749  1.000 29.57057 ? 1661 ARG A HH22 1 
ATOM   3145 N  N    . PRO A 1 203 ? -23.17571 -10.19403 -9.48828  1.000 10.97239 ? 1662 PRO A N    1 
ATOM   3146 C  CA   . PRO A 1 203 ? -23.46039 -8.81169  -9.87378  1.000 11.19084 ? 1662 PRO A CA   1 
ATOM   3147 C  C    . PRO A 1 203 ? -24.48281 -8.70835  -10.98161 1.000 11.10398 ? 1662 PRO A C    1 
ATOM   3148 O  O    . PRO A 1 203 ? -24.57264 -9.58151  -11.85047 1.000 11.32506 ? 1662 PRO A O    1 
ATOM   3149 C  CB   . PRO A 1 203 ? -22.10176 -8.30644  -10.38477 1.000 10.85132 ? 1662 PRO A CB   1 
ATOM   3150 C  CG   . PRO A 1 203 ? -21.08687 -9.23049  -9.75906  1.000 10.94080 ? 1662 PRO A CG   1 
ATOM   3151 C  CD   . PRO A 1 203 ? -21.77381 -10.56599 -9.74230  1.000 10.99607 ? 1662 PRO A CD   1 
ATOM   3152 H  HA   . PRO A 1 203 ? -23.74968 -8.31904  -9.08987  1.000 13.43180 ? 1662 PRO A HA   1 
ATOM   3153 H  HB2  . PRO A 1 203 ? -22.07149 -8.36058  -11.35278 1.000 13.02438 ? 1662 PRO A HB2  1 
ATOM   3154 H  HB3  . PRO A 1 203 ? -21.96086 -7.39021  -10.09917 1.000 13.02438 ? 1662 PRO A HB3  1 
ATOM   3155 H  HG2  . PRO A 1 203 ? -20.28135 -9.25734  -10.29880 1.000 13.13176 ? 1662 PRO A HG2  1 
ATOM   3156 H  HG3  . PRO A 1 203 ? -20.87421 -8.93434  -8.86019  1.000 13.13176 ? 1662 PRO A HG3  1 
ATOM   3157 H  HD2  . PRO A 1 203 ? -21.68150 -11.01674 -10.59624 1.000 13.19809 ? 1662 PRO A HD2  1 
ATOM   3158 H  HD3  . PRO A 1 203 ? -21.42743 -11.12779 -9.03146  1.000 13.19809 ? 1662 PRO A HD3  1 
ATOM   3159 N  N    . GLU A 1 204 ? -25.25708 -7.62716  -10.96849 1.000 11.11714 ? 1663 GLU A N    1 
ATOM   3160 C  CA   A GLU A 1 204 ? -26.29778 -7.45048  -11.96745 1.000 11.83565 ? 1663 GLU A CA   1 
ATOM   3161 C  CA   B GLU A 1 204 ? -26.30285 -7.46623  -11.96459 0.000 11.34349 ? 1663 GLU A CA   1 
ATOM   3162 C  C    . GLU A 1 204 ? -25.70437 -7.28240  -13.35690 1.000 11.69090 ? 1663 GLU A C    1 
ATOM   3163 O  O    . GLU A 1 204 ? -24.51816 -6.99136  -13.52956 1.000 13.01737 ? 1663 GLU A O    1 
ATOM   3164 C  CB   A GLU A 1 204 ? -27.14784 -6.22212  -11.65437 1.000 13.68324 ? 1663 GLU A CB   1 
ATOM   3165 C  CB   B GLU A 1 204 ? -27.19887 -6.28285  -11.59970 0.000 11.44876 ? 1663 GLU A CB   1 
ATOM   3166 C  CG   A GLU A 1 204 ? -26.43285 -4.89144  -11.73764 1.000 16.81519 ? 1663 GLU A CG   1 
ATOM   3167 C  CG   B GLU A 1 204 ? -26.52842 -4.92181  -11.69016 0.000 11.62247 ? 1663 GLU A CG   1 
ATOM   3168 C  CD   A GLU A 1 204 ? -27.36524 -3.74804  -11.28858 1.000 20.54722 ? 1663 GLU A CD   1 
ATOM   3169 C  CD   B GLU A 1 204 ? -27.43515 -3.80033  -11.21312 0.000 11.88829 ? 1663 GLU A CD   1 
ATOM   3170 O  OE1  A GLU A 1 204 ? -28.32227 -3.99301  -10.53133 1.000 21.87633 ? 1663 GLU A OE1  1 
ATOM   3171 O  OE1  B GLU A 1 204 ? -28.27718 -4.05057  -10.32571 0.000 12.12253 ? 1663 GLU A OE1  1 
ATOM   3172 O  OE2  A GLU A 1 204 ? -27.12782 -2.59685  -11.63725 1.000 22.22637 ? 1663 GLU A OE2  1 
ATOM   3173 O  OE2  B GLU A 1 204 ? -27.30920 -2.66683  -11.72468 0.000 12.04883 ? 1663 GLU A OE2  1 
ATOM   3174 H  H    A GLU A 1 204 ? -25.19862 -6.98832  -10.39573 1.000 13.34337 ? 1663 GLU A H    1 
ATOM   3175 H  H    B GLU A 1 204 ? -25.19611 -6.98377  -10.40111 0.000 13.34337 ? 1663 GLU A H    1 
ATOM   3176 H  HA   A GLU A 1 204 ? -26.86201 -8.23945  -11.95905 1.000 14.20558 ? 1663 GLU A HA   1 
ATOM   3177 H  HA   B GLU A 1 204 ? -26.85538 -8.26307  -11.99027 0.000 13.61498 ? 1663 GLU A HA   1 
ATOM   3178 H  HB2  A GLU A 1 204 ? -27.88445 -6.19309  -12.28482 1.000 16.42269 ? 1663 GLU A HB2  1 
ATOM   3179 H  HB2  B GLU A 1 204 ? -27.95808 -6.27440  -12.20337 0.000 13.74131 ? 1663 GLU A HB2  1 
ATOM   3180 H  HB3  A GLU A 1 204 ? -27.48820 -6.30998  -10.75030 1.000 16.42269 ? 1663 GLU A HB3  1 
ATOM   3181 H  HB3  B GLU A 1 204 ? -27.50295 -6.39773  -10.68579 0.000 13.74131 ? 1663 GLU A HB3  1 
ATOM   3182 H  HG2  A GLU A 1 204 ? -25.65601 -4.90335  -11.15689 1.000 20.18103 ? 1663 GLU A HG2  1 
ATOM   3183 H  HG2  B GLU A 1 204 ? -25.73192 -4.92233  -11.13655 0.000 13.94976 ? 1663 GLU A HG2  1 
ATOM   3184 H  HG3  A GLU A 1 204 ? -26.15978 -4.72632  -12.65364 1.000 20.18103 ? 1663 GLU A HG3  1 
ATOM   3185 H  HG3  B GLU A 1 204 ? -26.29034 -4.74544  -12.61380 0.000 13.94976 ? 1663 GLU A HG3  1 
ATOM   3186 N  N    . LEU A 1 205 ? -26.54956 -7.47098  -14.36563 1.000 11.69879 ? 1664 LEU A N    1 
ATOM   3187 C  CA   . LEU A 1 205 ? -26.15561 -7.18604  -15.73942 1.000 12.08042 ? 1664 LEU A CA   1 
ATOM   3188 C  C    . LEU A 1 205 ? -25.76046 -5.72427  -15.86399 1.000 12.81998 ? 1664 LEU A C    1 
ATOM   3189 O  O    . LEU A 1 205 ? -26.34991 -4.84162  -15.22906 1.000 13.69640 ? 1664 LEU A O    1 
ATOM   3190 C  CB   . LEU A 1 205 ? -27.26816 -7.53789  -16.71650 1.000 12.96473 ? 1664 LEU A CB   1 
ATOM   3191 C  CG   . LEU A 1 205 ? -27.58724 -9.02109  -16.84608 1.000 13.07264 ? 1664 LEU A CG   1 
ATOM   3192 C  CD1  . LEU A 1 205 ? -28.66315 -9.23409  -17.90677 1.000 13.71745 ? 1664 LEU A CD1  1 
ATOM   3193 C  CD2  . LEU A 1 205 ? -26.34461 -9.83626  -17.19796 1.000 13.49374 ? 1664 LEU A CD2  1 
ATOM   3194 H  H    . LEU A 1 205 ? -27.35437 -7.76219  -14.28150 1.000 14.04135 ? 1664 LEU A H    1 
ATOM   3195 H  HA   . LEU A 1 205 ? -25.39325 -7.73525  -15.98039 1.000 14.49930 ? 1664 LEU A HA   1 
ATOM   3196 H  HB2  . LEU A 1 205 ? -28.07944 -7.09238  -16.42626 1.000 15.56047 ? 1664 LEU A HB2  1 
ATOM   3197 H  HB3  . LEU A 1 205 ? -27.01160 -7.21988  -17.59624 1.000 15.56047 ? 1664 LEU A HB3  1 
ATOM   3198 H  HG   . LEU A 1 205 ? -27.91390 -9.33802  -15.98950 1.000 15.68997 ? 1664 LEU A HG   1 
ATOM   3199 H  HD11 . LEU A 1 205 ? -28.86081 -10.18161 -17.97028 1.000 16.46374 ? 1664 LEU A HD11 1 
ATOM   3200 H  HD12 . LEU A 1 205 ? -29.46113 -8.74625  -17.64959 1.000 16.46374 ? 1664 LEU A HD12 1 
ATOM   3201 H  HD13 . LEU A 1 205 ? -28.33559 -8.90667  -18.75906 1.000 16.46374 ? 1664 LEU A HD13 1 
ATOM   3202 H  HD21 . LEU A 1 205 ? -26.61758 -10.72596 -17.47147 1.000 16.19529 ? 1664 LEU A HD21 1 
ATOM   3203 H  HD22 . LEU A 1 205 ? -25.87379 -9.39705  -17.92344 1.000 16.19529 ? 1664 LEU A HD22 1 
ATOM   3204 H  HD23 . LEU A 1 205 ? -25.77161 -9.89144  -16.41724 1.000 16.19529 ? 1664 LEU A HD23 1 
ATOM   3205 N  N    . GLY A 1 206 ? -24.72823 -5.48313  -16.66188 1.000 12.83051 ? 1665 GLY A N    1 
ATOM   3206 C  CA   . GLY A 1 206 ? -24.17574 -4.16205  -16.82266 1.000 12.98579 ? 1665 GLY A CA   1 
ATOM   3207 C  C    . GLY A 1 206 ? -24.70916 -3.47303  -18.06409 1.000 12.90683 ? 1665 GLY A C    1 
ATOM   3208 O  O    . GLY A 1 206 ? -25.41580 -4.04989  -18.89310 1.000 13.54901 ? 1665 GLY A O    1 
ATOM   3209 H  H    . GLY A 1 206 ? -24.32781 -6.08565  -17.12689 1.000 15.39940 ? 1665 GLY A H    1 
ATOM   3210 H  HA2  . GLY A 1 206 ? -24.40138 -3.62137  -16.04958 1.000 15.58574 ? 1665 GLY A HA2  1 
ATOM   3211 H  HA3  . GLY A 1 206 ? -23.21032 -4.22237  -16.89493 1.000 15.58574 ? 1665 GLY A HA3  1 
ATOM   3212 N  N    . SER A 1 207 ? -24.31315 -2.21673  -18.19813 1.000 13.49901 ? 1666 SER A N    1 
ATOM   3213 C  CA   . SER A 1 207 ? -24.63784 -1.47115  -19.39928 1.000 14.09645 ? 1666 SER A CA   1 
ATOM   3214 C  C    . SER A 1 207 ? -23.77357 -1.95236  -20.56342 1.000 14.42807 ? 1666 SER A C    1 
ATOM   3215 O  O    . SER A 1 207 ? -22.79334 -2.68779  -20.39338 1.000 14.54913 ? 1666 SER A O    1 
ATOM   3216 C  CB   . SER A 1 207 ? -24.32645 0.00699   -19.20025 1.000 14.57282 ? 1666 SER A CB   1 
ATOM   3217 O  OG   . SER A 1 207 ? -22.91407 0.18033   -19.08309 1.000 14.41491 ? 1666 SER A OG   1 
ATOM   3218 H  H    . SER A 1 207 ? -23.85982 -1.77840  -17.61336 1.000 16.20161 ? 1666 SER A H    1 
ATOM   3219 H  HA   . SER A 1 207 ? -25.57933 -1.59750  -19.59560 1.000 16.91853 ? 1666 SER A HA   1 
ATOM   3220 H  HB2  . SER A 1 207 ? -24.65017 0.50980   -19.96398 1.000 17.49018 ? 1666 SER A HB2  1 
ATOM   3221 H  HB3  . SER A 1 207 ? -24.75752 0.32045   -18.38981 1.000 17.49018 ? 1666 SER A HB3  1 
ATOM   3222 H  HG   . SER A 1 207 ? -22.73335 0.99148   -18.96071 1.000 17.30069 ? 1666 SER A HG   1 
ATOM   3223 N  N    . ARG A 1 208 ? -24.13833 -1.51301  -21.76860 1.000 15.20974 ? 1667 ARG A N    1 
ATOM   3224 C  CA   . ARG A 1 208 ? -23.28901 -1.75698  -22.93287 1.000 16.27302 ? 1667 ARG A CA   1 
ATOM   3225 C  C    . ARG A 1 208 ? -21.87254 -1.23745  -22.69899 1.000 16.07563 ? 1667 ARG A C    1 
ATOM   3226 O  O    . ARG A 1 208 ? -20.89791 -1.84873  -23.14824 1.000 16.03352 ? 1667 ARG A O    1 
ATOM   3227 C  CB   . ARG A 1 208 ? -23.88368 -1.11928  -24.19171 1.000 17.93111 ? 1667 ARG A CB   1 
ATOM   3228 H  H    . ARG A 1 208 ? -24.86099 -1.07809  -21.93657 1.000 18.25448 ? 1667 ARG A H    1 
ATOM   3229 H  HA   . ARG A 1 208 ? -23.24976 -2.71464  -23.08204 1.000 19.53042 ? 1667 ARG A HA   1 
ATOM   3230 N  N    A GLN A 1 209 ? -21.74346 -0.10550  -22.00389 0.656 15.75981 ? 1668 GLN A N    1 
ATOM   3231 N  N    B GLN A 1 209 ? -21.73592 -0.09992  -22.01091 0.344 16.17564 ? 1668 GLN A N    1 
ATOM   3232 C  CA   A GLN A 1 209 ? -20.42432 0.44773   -21.72647 0.656 16.30461 ? 1668 GLN A CA   1 
ATOM   3233 C  CA   B GLN A 1 209 ? -20.40112 0.42756   -21.74145 0.344 16.81519 ? 1668 GLN A CA   1 
ATOM   3234 C  C    A GLN A 1 209 ? -19.63842 -0.42830  -20.75496 0.656 14.28068 ? 1668 GLN A C    1 
ATOM   3235 C  C    B GLN A 1 209 ? -19.63000 -0.46436  -20.77383 0.344 14.70968 ? 1668 GLN A C    1 
ATOM   3236 O  O    A GLN A 1 209 ? -18.40990 -0.51725  -20.86823 0.656 14.64914 ? 1668 GLN A O    1 
ATOM   3237 O  O    B GLN A 1 209 ? -18.40612 -0.60223  -20.89488 0.344 14.97287 ? 1668 GLN A O    1 
ATOM   3238 C  CB   A GLN A 1 209 ? -20.59222 1.86323   -21.17716 0.656 19.43919 ? 1668 GLN A CB   1 
ATOM   3239 C  CB   B GLN A 1 209 ? -20.48982 1.85389   -21.20371 0.344 19.84187 ? 1668 GLN A CB   1 
ATOM   3240 C  CG   A GLN A 1 209 ? -21.18637 2.86960   -22.17629 0.656 22.90803 ? 1668 GLN A CG   1 
ATOM   3241 C  CG   B GLN A 1 209 ? -20.87948 2.88232   -22.24566 0.344 23.11595 ? 1668 GLN A CG   1 
ATOM   3242 C  CD   A GLN A 1 209 ? -22.63231 2.55889   -22.65409 0.656 25.59782 ? 1668 GLN A CD   1 
ATOM   3243 C  CD   B GLN A 1 209 ? -20.46821 4.28752   -21.85274 0.344 25.98471 ? 1668 GLN A CD   1 
ATOM   3244 O  OE1  A GLN A 1 209 ? -23.55164 2.24981   -21.86632 0.656 25.01881 ? 1668 GLN A OE1  1 
ATOM   3245 O  OE1  B GLN A 1 209 ? -19.42787 4.78379   -22.28288 0.344 26.87692 ? 1668 GLN A OE1  1 
ATOM   3246 N  NE2  A GLN A 1 209 ? -22.82496 2.65547   -23.97031 0.656 27.57438 ? 1668 GLN A NE2  1 
ATOM   3247 N  NE2  B GLN A 1 209 ? -21.27967 4.93297   -21.02495 0.344 27.32961 ? 1668 GLN A NE2  1 
ATOM   3248 H  H    A GLN A 1 209 ? -22.39738 0.35417   -21.68657 0.656 18.91456 ? 1668 GLN A H    1 
ATOM   3249 H  H    B GLN A 1 209 ? -22.38363 0.37157   -21.69824 0.344 19.41357 ? 1668 GLN A H    1 
ATOM   3250 H  HA   A GLN A 1 209 ? -19.90742 0.49555   -22.54588 0.656 19.56833 ? 1668 GLN A HA   1 
ATOM   3251 H  HA   B GLN A 1 209 ? -19.91001 0.45508   -22.57749 0.344 20.18103 ? 1668 GLN A HA   1 
ATOM   3252 H  HB2  A GLN A 1 209 ? -21.18429 1.82835   -20.40961 0.656 23.32983 ? 1668 GLN A HB2  1 
ATOM   3253 H  HB2  B GLN A 1 209 ? -21.15666 1.87976   -20.49975 0.344 23.81304 ? 1668 GLN A HB2  1 
ATOM   3254 H  HB3  A GLN A 1 209 ? -19.72125 2.19587   -20.90946 0.656 23.32983 ? 1668 GLN A HB3  1 
ATOM   3255 H  HB3  B GLN A 1 209 ? -19.62311 2.10684   -20.84913 0.344 23.81304 ? 1668 GLN A HB3  1 
ATOM   3256 H  HG2  A GLN A 1 209 ? -21.20252 3.74405   -21.75679 0.656 27.49243 ? 1668 GLN A HG2  1 
ATOM   3257 H  HG2  B GLN A 1 209 ? -20.44452 2.66451   -23.08487 0.344 27.74194 ? 1668 GLN A HG2  1 
ATOM   3258 H  HG3  A GLN A 1 209 ? -20.62015 2.88975   -22.96361 0.656 27.49243 ? 1668 GLN A HG3  1 
ATOM   3259 H  HG3  B GLN A 1 209 ? -21.84283 2.87064   -22.35847 0.344 27.74194 ? 1668 GLN A HG3  1 
ATOM   3260 H  HE21 A GLN A 1 209 ? -22.17254 2.87615   -24.48533 0.656 33.09205 ? 1668 GLN A HE21 1 
ATOM   3261 H  HE21 B GLN A 1 209 ? -21.99595 4.55144   -20.74041 0.344 32.79833 ? 1668 GLN A HE21 1 
ATOM   3262 H  HE22 A GLN A 1 209 ? -23.60160 2.49706   -24.30399 0.656 33.09205 ? 1668 GLN A HE22 1 
ATOM   3263 H  HE22 B GLN A 1 209 ? -21.08936 5.73289   -20.77292 0.344 32.79833 ? 1668 GLN A HE22 1 
ATOM   3264 N  N    . ASP A 1 210 ? -20.31824 -1.07096  -19.80378 1.000 13.22792 ? 1669 ASP A N    1 
ATOM   3265 C  CA   . ASP A 1 210 ? -19.65545 -2.02487  -18.92440 1.000 11.38560 ? 1669 ASP A CA   1 
ATOM   3266 C  C    . ASP A 1 210 ? -19.12557 -3.20596  -19.72617 1.000 11.06977 ? 1669 ASP A C    1 
ATOM   3267 O  O    . ASP A 1 210 ? -17.96624 -3.60915  -19.58360 1.000 11.38296 ? 1669 ASP A O    1 
ATOM   3268 C  CB   . ASP A 1 210 ? -20.62639 -2.54191  -17.85973 1.000 11.44613 ? 1669 ASP A CB   1 
ATOM   3269 C  CG   . ASP A 1 210 ? -20.91919 -1.51040  -16.76232 1.000 12.04620 ? 1669 ASP A CG   1 
ATOM   3270 O  OD1  . ASP A 1 210 ? -19.95818 -0.85528  -16.30063 1.000 12.70944 ? 1669 ASP A OD1  1 
ATOM   3271 O  OD2  . ASP A 1 210 ? -22.09510 -1.38635  -16.33906 1.000 12.83577 ? 1669 ASP A OD2  1 
ATOM   3272 H  H    . ASP A 1 210 ? -21.15866 -0.96945  -19.65216 1.000 15.87630 ? 1669 ASP A H    1 
ATOM   3273 H  HA   . ASP A 1 210 ? -18.92217 -1.57077  -18.48057 1.000 13.66552 ? 1669 ASP A HA   1 
ATOM   3274 H  HB2  . ASP A 1 210 ? -21.46710 -2.77213  -18.28529 1.000 13.73815 ? 1669 ASP A HB2  1 
ATOM   3275 H  HB3  . ASP A 1 210 ? -20.24248 -3.32634  -17.43762 1.000 13.73815 ? 1669 ASP A HB3  1 
ATOM   3276 N  N    . VAL A 1 211 ? -19.97679 -3.78478  -20.56834 1.000 11.30138 ? 1670 VAL A N    1 
ATOM   3277 C  CA   . VAL A 1 211 ? -19.55551 -4.93635  -21.35506 1.000 12.37782 ? 1670 VAL A CA   1 
ATOM   3278 C  C    . VAL A 1 211 ? -18.37330 -4.57174  -22.23600 1.000 13.12528 ? 1670 VAL A C    1 
ATOM   3279 O  O    . VAL A 1 211 ? -17.38929 -5.30982  -22.32288 1.000 12.98316 ? 1670 VAL A O    1 
ATOM   3280 C  CB   . VAL A 1 211 ? -20.73525 -5.44230  -22.19465 1.000 12.35150 ? 1670 VAL A CB   1 
ATOM   3281 C  CG1  . VAL A 1 211 ? -20.28522 -6.51169  -23.18084 1.000 12.73839 ? 1670 VAL A CG1  1 
ATOM   3282 C  CG2  . VAL A 1 211 ? -21.86050 -5.98452  -21.31280 1.000 12.62522 ? 1670 VAL A CG2  1 
ATOM   3283 H  H    . VAL A 1 211 ? -20.78890 -3.53429  -20.70002 1.000 13.56445 ? 1670 VAL A H    1 
ATOM   3284 H  HA   . VAL A 1 211 ? -19.27184 -5.64249  -20.75356 1.000 14.85618 ? 1670 VAL A HA   1 
ATOM   3285 H  HB   . VAL A 1 211 ? -21.08309 -4.68746  -22.69476 1.000 14.82460 ? 1670 VAL A HB   1 
ATOM   3286 H  HG11 . VAL A 1 211 ? -21.06310 -6.99769  -23.49642 1.000 15.28886 ? 1670 VAL A HG11 1 
ATOM   3287 H  HG12 . VAL A 1 211 ? -19.83692 -6.08429  -23.92733 1.000 15.28886 ? 1670 VAL A HG12 1 
ATOM   3288 H  HG13 . VAL A 1 211 ? -19.67563 -7.11844  -22.73234 1.000 15.28886 ? 1670 VAL A HG13 1 
ATOM   3289 H  HG21 . VAL A 1 211 ? -22.58728 -6.28780  -21.87911 1.000 15.15306 ? 1670 VAL A HG21 1 
ATOM   3290 H  HG22 . VAL A 1 211 ? -21.52032 -6.72482  -20.78635 1.000 15.15306 ? 1670 VAL A HG22 1 
ATOM   3291 H  HG23 . VAL A 1 211 ? -22.17113 -5.27693  -20.72653 1.000 15.15306 ? 1670 VAL A HG23 1 
ATOM   3292 N  N    A GLU A 1 212 ? -18.45814 -3.42733  -22.91799 0.484 13.76220 ? 1671 GLU A N    1 
ATOM   3293 N  N    B GLU A 1 212 ? -18.46001 -3.42604  -22.91966 0.516 13.69377 ? 1671 GLU A N    1 
ATOM   3294 C  CA   A GLU A 1 212 ? -17.37415 -3.03381  -23.80909 0.484 15.52293 ? 1671 GLU A CA   1 
ATOM   3295 C  CA   B GLU A 1 212 ? -17.37855 -3.01350  -23.80606 0.516 15.44398 ? 1671 GLU A CA   1 
ATOM   3296 C  C    A GLU A 1 212 ? -16.07746 -2.81299  -23.03421 0.484 14.00433 ? 1671 GLU A C    1 
ATOM   3297 C  C    B GLU A 1 212 ? -16.08178 -2.81113  -23.03202 0.516 13.94643 ? 1671 GLU A C    1 
ATOM   3298 O  O    A GLU A 1 212 ? -14.98658 -3.11709  -23.53318 0.484 13.99907 ? 1671 GLU A O    1 
ATOM   3299 O  O    B GLU A 1 212 ? -14.99657 -3.12651  -23.53435 0.516 13.94643 ? 1671 GLU A O    1 
ATOM   3300 C  CB   A GLU A 1 212 ? -17.76904 -1.79217  -24.60571 0.484 19.65238 ? 1671 GLU A CB   1 
ATOM   3301 C  CB   B GLU A 1 212 ? -17.79675 -1.74584  -24.55523 0.516 19.62079 ? 1671 GLU A CB   1 
ATOM   3302 C  CG   A GLU A 1 212 ? -18.89693 -2.04935  -25.60234 0.484 24.12660 ? 1671 GLU A CG   1 
ATOM   3303 C  CG   B GLU A 1 212 ? -16.66801 -0.82723  -25.00908 0.516 24.21082 ? 1671 GLU A CG   1 
ATOM   3304 C  CD   A GLU A 1 212 ? -19.40726 -0.78932  -26.28617 0.484 27.99811 ? 1671 GLU A CD   1 
ATOM   3305 C  CD   B GLU A 1 212 ? -17.18240 0.47315   -25.63383 0.516 27.95074 ? 1671 GLU A CD   1 
ATOM   3306 O  OE1  A GLU A 1 212 ? -18.86024 0.30842   -26.03623 0.484 29.26142 ? 1671 GLU A OE1  1 
ATOM   3307 O  OE1  B GLU A 1 212 ? -17.47820 1.43739   -24.89147 0.516 29.11403 ? 1671 GLU A OE1  1 
ATOM   3308 O  OE2  A GLU A 1 212 ? -20.37544 -0.90431  -27.07125 0.484 29.29827 ? 1671 GLU A OE2  1 
ATOM   3309 O  OE2  B GLU A 1 212 ? -17.29057 0.52036   -26.87741 0.516 29.31669 ? 1671 GLU A OE2  1 
ATOM   3310 H  H    A GLU A 1 212 ? -19.11732 -2.87618  -22.88172 0.484 16.51743 ? 1671 GLU A H    1 
ATOM   3311 H  H    B GLU A 1 212 ? -19.12443 -2.88103  -22.88629 0.516 16.43532 ? 1671 GLU A H    1 
ATOM   3312 H  HA   A GLU A 1 212 ? -17.21460 -3.74584  -24.44819 0.484 18.63032 ? 1671 GLU A HA   1 
ATOM   3313 H  HA   B GLU A 1 212 ? -17.21023 -3.70467  -24.46550 0.516 18.53557 ? 1671 GLU A HA   1 
ATOM   3314 H  HB2  A GLU A 1 212 ? -18.06672 -1.10520  -23.98898 0.484 23.58565 ? 1671 GLU A HB2  1 
ATOM   3315 H  HB2  B GLU A 1 212 ? -18.28517 -2.01191  -25.34993 0.516 23.54775 ? 1671 GLU A HB2  1 
ATOM   3316 H  HB3  A GLU A 1 212 ? -16.99702 -1.47969  -25.10294 0.484 23.58565 ? 1671 GLU A HB3  1 
ATOM   3317 H  HB3  B GLU A 1 212 ? -18.37088 -1.22561  -23.97160 0.516 23.54775 ? 1671 GLU A HB3  1 
ATOM   3318 H  HG2  A GLU A 1 212 ? -18.57378 -2.65020  -26.29188 0.484 28.95471 ? 1671 GLU A HG2  1 
ATOM   3319 H  HG2  B GLU A 1 212 ? -16.12009 -0.59631  -24.24268 0.516 29.05578 ? 1671 GLU A HG2  1 
ATOM   3320 H  HG3  A GLU A 1 212 ? -19.64289 -2.45405  -25.13259 0.484 28.95471 ? 1671 GLU A HG3  1 
ATOM   3321 H  HG3  B GLU A 1 212 ? -16.13208 -1.28833  -25.67320 0.516 29.05578 ? 1671 GLU A HG3  1 
ATOM   3322 N  N    . ALA A 1 213 ? -16.17525 -2.28556  -21.81151 1.000 13.39110 ? 1672 ALA A N    1 
ATOM   3323 C  CA   . ALA A 1 213 ? -14.98568 -2.06203  -20.99893 1.000 12.42783 ? 1672 ALA A CA   1 
ATOM   3324 C  C    . ALA A 1 213 ? -14.31613 -3.37613  -20.62088 1.000 11.79617 ? 1672 ALA A C    1 
ATOM   3325 O  O    . ALA A 1 213 ? -13.08554 -3.45547  -20.57979 1.000 12.18832 ? 1672 ALA A O    1 
ATOM   3326 C  CB   . ALA A 1 213 ? -15.32380 -1.26319  -19.73924 1.000 12.74102 ? 1672 ALA A CB   1 
ATOM   3327 H  H    . ALA A 1 213 ? -16.91331 -2.05250  -21.43662 1.000 16.07212 ? 1672 ALA A H    1 
ATOM   3328 H  HA   . ALA A 1 213 ? -14.36174 -1.53645  -21.52368 1.000 14.91619 ? 1672 ALA A HA   1 
ATOM   3329 H  HB1  . ALA A 1 213 ? -14.51565 -1.13975  -19.21717 1.000 15.29202 ? 1672 ALA A HB1  1 
ATOM   3330 H  HB2  . ALA A 1 213 ? -15.68449 -0.40112  -19.99931 1.000 15.29202 ? 1672 ALA A HB2  1 
ATOM   3331 H  HB3  . ALA A 1 213 ? -15.98070 -1.75387  -19.22096 1.000 15.29202 ? 1672 ALA A HB3  1 
ATOM   3332 N  N    . LEU A 1 214 ? -15.10057 -4.41376  -20.31943 1.000 11.46982 ? 1673 LEU A N    1 
ATOM   3333 C  CA   . LEU A 1 214 ? -14.49129 -5.70020  -19.99181 1.000 10.90396 ? 1673 LEU A CA   1 
ATOM   3334 C  C    . LEU A 1 214 ? -13.73521 -6.25531  -21.19604 1.000 11.17504 ? 1673 LEU A C    1 
ATOM   3335 O  O    . LEU A 1 214 ? -12.58580 -6.71625  -21.06925 1.000 11.79880 ? 1673 LEU A O    1 
ATOM   3336 C  CB   . LEU A 1 214 ? -15.56540 -6.66297  -19.46811 1.000 10.80658 ? 1673 LEU A CB   1 
ATOM   3337 C  CG   . LEU A 1 214 ? -16.21831 -6.21732  -18.14782 1.000 11.16978 ? 1673 LEU A CG   1 
ATOM   3338 C  CD1  . LEU A 1 214 ? -17.31899 -7.24320  -17.80026 1.000 11.92513 ? 1673 LEU A CD1  1 
ATOM   3339 C  CD2  . LEU A 1 214 ? -15.24312 -6.10411  -17.00839 1.000 10.96976 ? 1673 LEU A CD2  1 
ATOM   3340 H  H    . LEU A 1 214 ? -15.96018 -4.39839  -20.29851 1.000 13.76658 ? 1673 LEU A H    1 
ATOM   3341 H  HA   . LEU A 1 214 ? -13.84395 -5.59253  -19.27748 1.000 13.08755 ? 1673 LEU A HA   1 
ATOM   3342 H  HB2  . LEU A 1 214 ? -16.26663 -6.73690  -20.13422 1.000 12.97069 ? 1673 LEU A HB2  1 
ATOM   3343 H  HB3  . LEU A 1 214 ? -15.15762 -7.53020  -19.31802 1.000 12.97069 ? 1673 LEU A HB3  1 
ATOM   3344 H  HG   . LEU A 1 214 ? -16.58599 -5.32737  -18.26485 1.000 13.40653 ? 1673 LEU A HG   1 
ATOM   3345 H  HD11 . LEU A 1 214 ? -17.74195 -6.98253  -16.96715 1.000 14.31296 ? 1673 LEU A HD11 1 
ATOM   3346 H  HD12 . LEU A 1 214 ? -17.97525 -7.25642  -18.51443 1.000 14.31296 ? 1673 LEU A HD12 1 
ATOM   3347 H  HD13 . LEU A 1 214 ? -16.91504 -8.12003  -17.70595 1.000 14.31296 ? 1673 LEU A HD13 1 
ATOM   3348 H  HD21 . LEU A 1 214 ? -15.73528 -5.96568  -16.18407 1.000 13.16650 ? 1673 LEU A HD21 1 
ATOM   3349 H  HD22 . LEU A 1 214 ? -14.72698 -6.92345  -16.95187 1.000 13.16650 ? 1673 LEU A HD22 1 
ATOM   3350 H  HD23 . LEU A 1 214 ? -14.65280 -5.35190  -17.17150 1.000 13.16650 ? 1673 LEU A HD23 1 
ATOM   3351 N  N    . TRP A 1 215 ? -14.34736 -6.21392  -22.38232 1.000 10.96186 ? 1674 TRP A N    1 
ATOM   3352 C  CA   . TRP A 1 215 ? -13.67351 -6.68963  -23.58753 1.000 11.67247 ? 1674 TRP A CA   1 
ATOM   3353 C  C    . TRP A 1 215 ? -12.41984 -5.86418  -23.87374 1.000 12.19359 ? 1674 TRP A C    1 
ATOM   3354 O  O    . TRP A 1 215 ? -11.35995 -6.41734  -24.19211 1.000 12.75418 ? 1674 TRP A O    1 
ATOM   3355 C  CB   . TRP A 1 215 ? -14.62245 -6.64731  -24.79290 1.000 12.33834 ? 1674 TRP A CB   1 
ATOM   3356 C  CG   . TRP A 1 215 ? -15.58307 -7.78374  -24.78472 1.000 12.26728 ? 1674 TRP A CG   1 
ATOM   3357 C  CD1  . TRP A 1 215 ? -16.89949 -7.74244  -24.42106 1.000 12.23833 ? 1674 TRP A CD1  1 
ATOM   3358 C  CD2  . TRP A 1 215 ? -15.31378 -9.13286  -25.15855 1.000 12.89367 ? 1674 TRP A CD2  1 
ATOM   3359 N  NE1  . TRP A 1 215 ? -17.45870 -8.98830  -24.53151 1.000 12.65154 ? 1674 TRP A NE1  1 
ATOM   3360 C  CE2  . TRP A 1 215 ? -16.50153 -9.86075  -24.98265 1.000 13.16476 ? 1674 TRP A CE2  1 
ATOM   3361 C  CE3  . TRP A 1 215 ? -14.17202 -9.80269  -25.61978 1.000 13.30161 ? 1674 TRP A CE3  1 
ATOM   3362 C  CZ2  . TRP A 1 215 ? -16.58350 -11.21087 -25.25575 1.000 13.42268 ? 1674 TRP A CZ2  1 
ATOM   3363 C  CZ3  . TRP A 1 215 ? -14.25281 -11.13540 -25.87351 1.000 13.96485 ? 1674 TRP A CZ3  1 
ATOM   3364 C  CH2  . TRP A 1 215 ? -15.44331 -11.83408 -25.69149 1.000 13.82536 ? 1674 TRP A CH2  1 
ATOM   3365 H  H    . TRP A 1 215 ? -15.14411 -5.91806  -22.51372 1.000 13.15703 ? 1674 TRP A H    1 
ATOM   3366 H  HA   . TRP A 1 215 ? -13.41316 -7.61368  -23.44873 1.000 14.00976 ? 1674 TRP A HA   1 
ATOM   3367 H  HB2  . TRP A 1 215 ? -15.12967 -5.82080  -24.77060 1.000 14.80881 ? 1674 TRP A HB2  1 
ATOM   3368 H  HB3  . TRP A 1 215 ? -14.10221 -6.69535  -25.61018 1.000 14.80881 ? 1674 TRP A HB3  1 
ATOM   3369 H  HD1  . TRP A 1 215 ? -17.35045 -6.97941  -24.13944 1.000 14.68879 ? 1674 TRP A HD1  1 
ATOM   3370 H  HE1  . TRP A 1 215 ? -18.27446 -9.18979  -24.34835 1.000 15.18464 ? 1674 TRP A HE1  1 
ATOM   3371 H  HE3  . TRP A 1 215 ? -13.37381 -9.34349  -25.74977 1.000 15.96474 ? 1674 TRP A HE3  1 
ATOM   3372 H  HZ2  . TRP A 1 215 ? -17.38000 -11.67883 -25.14849 1.000 16.11001 ? 1674 TRP A HZ2  1 
ATOM   3373 H  HZ3  . TRP A 1 215 ? -13.49882 -11.58917 -26.17434 1.000 16.76062 ? 1674 TRP A HZ3  1 
ATOM   3374 H  HH2  . TRP A 1 215 ? -15.46535 -12.74651 -25.87007 1.000 16.59323 ? 1674 TRP A HH2  1 
ATOM   3375 N  N    . GLU A 1 216 ? -12.51327 -4.53899  -23.75323 1.000 12.31466 ? 1675 GLU A N    1 
ATOM   3376 C  CA   A GLU A 1 216 ? -11.35843 -3.70443  -24.05904 0.537 13.08317 ? 1675 GLU A CA   1 
ATOM   3377 C  CA   B GLU A 1 216 ? -11.36504 -3.68503  -24.04628 0.463 12.89104 ? 1675 GLU A CA   1 
ATOM   3378 C  C    . GLU A 1 216 ? -10.22032 -3.96823  -23.08667 1.000 12.34361 ? 1675 GLU A C    1 
ATOM   3379 O  O    . GLU A 1 216 ? -9.04432  -3.84115  -23.46345 1.000 13.08317 ? 1675 GLU A O    1 
ATOM   3380 C  CB   A GLU A 1 216 ? -11.76025 -2.23090  -24.04869 0.537 15.34923 ? 1675 GLU A CB   1 
ATOM   3381 C  CB   B GLU A 1 216 ? -11.79919 -2.21861  -23.95948 0.463 14.67283 ? 1675 GLU A CB   1 
ATOM   3382 C  CG   A GLU A 1 216 ? -12.62065 -1.85239  -25.23157 0.537 18.18115 ? 1675 GLU A CG   1 
ATOM   3383 C  CG   B GLU A 1 216 ? -10.67791 -1.18959  -23.98778 0.463 16.79151 ? 1675 GLU A CG   1 
ATOM   3384 C  CD   A GLU A 1 216 ? -13.01789 -0.38108  -25.24715 0.537 20.92358 ? 1675 GLU A CD   1 
ATOM   3385 C  CD   B GLU A 1 216 ? -10.06396 -1.01638  -25.35934 0.463 19.25496 ? 1675 GLU A CD   1 
ATOM   3386 O  OE1  A GLU A 1 216 ? -12.59344 0.38890   -24.35499 0.537 22.14215 ? 1675 GLU A OE1  1 
ATOM   3387 O  OE1  B GLU A 1 216 ? -10.65985 -1.48847  -26.35062 0.463 20.68144 ? 1675 GLU A OE1  1 
ATOM   3388 O  OE2  A GLU A 1 216 ? -13.74496 0.01471   -26.18283 0.537 21.83158 ? 1675 GLU A OE2  1 
ATOM   3389 O  OE2  B GLU A 1 216 ? -8.98313  -0.39777  -25.45031 0.463 20.72092 ? 1675 GLU A OE2  1 
ATOM   3390 H  H    A GLU A 1 216 ? -13.21620 -4.11150  -23.50275 0.537 14.78038 ? 1675 GLU A H    1 
ATOM   3391 H  H    B GLU A 1 216 ? -13.22022 -4.11567  -23.50701 0.463 14.78038 ? 1675 GLU A H    1 
ATOM   3392 H  HA   A GLU A 1 216 ? -11.03939 -3.91042  -24.95161 0.537 15.70260 ? 1675 GLU A HA   1 
ATOM   3393 H  HA   B GLU A 1 216 ? -11.04507 -3.85304  -24.94644 0.463 15.47205 ? 1675 GLU A HA   1 
ATOM   3394 H  HB2  A GLU A 1 216 ? -12.26310 -2.04637  -23.23999 0.537 18.42187 ? 1675 GLU A HB2  1 
ATOM   3395 H  HB2  B GLU A 1 216 ? -12.38107 -2.02949  -24.71217 0.463 17.61020 ? 1675 GLU A HB2  1 
ATOM   3396 H  HB3  A GLU A 1 216 ? -10.95891 -1.68487  -24.07294 0.537 18.42187 ? 1675 GLU A HB3  1 
ATOM   3397 H  HB3  B GLU A 1 216 ? -12.28192 -2.09394  -23.12742 0.463 17.61020 ? 1675 GLU A HB3  1 
ATOM   3398 H  HG2  A GLU A 1 216 ? -12.12963 -2.03601  -26.04771 0.537 21.82017 ? 1675 GLU A HG2  1 
ATOM   3399 H  HG2  B GLU A 1 216 ? -11.03209 -0.33069  -23.70895 0.463 20.15261 ? 1675 GLU A HG2  1 
ATOM   3400 H  HG3  A GLU A 1 216 ? -13.43463 -2.37946  -25.20840 0.537 21.82017 ? 1675 GLU A HG3  1 
ATOM   3401 H  HG3  B GLU A 1 216 ? -9.97629  -1.47210  -23.38048 0.463 20.15261 ? 1675 GLU A HG3  1 
ATOM   3402 N  N    . ASN A 1 217 ? -10.54401 -4.37665  -21.86173 1.000 11.49614 ? 1676 ASN A N    1 
ATOM   3403 C  CA   . ASN A 1 217 ? -9.58195  -4.65149  -20.80120 1.000 10.87501 ? 1676 ASN A CA   1 
ATOM   3404 C  C    . ASN A 1 217 ? -9.37050  -6.14166  -20.58663 1.000 10.68551 ? 1676 ASN A C    1 
ATOM   3405 O  O    . ASN A 1 217 ? -9.05470  -6.58028  -19.47650 1.000 11.39875 ? 1676 ASN A O    1 
ATOM   3406 C  CB   . ASN A 1 217 ? -9.97495  -3.93730  -19.51652 1.000 11.58036 ? 1676 ASN A CB   1 
ATOM   3407 C  CG   . ASN A 1 217 ? -9.80004  -2.44667  -19.64157 1.000 13.12265 ? 1676 ASN A CG   1 
ATOM   3408 O  OD1  . ASN A 1 217 ? -8.66617  -1.95504  -19.62371 1.000 14.37806 ? 1676 ASN A OD1  1 
ATOM   3409 N  ND2  . ASN A 1 217 ? -10.89965 -1.72266  -19.85438 1.000 13.70429 ? 1676 ASN A ND2  1 
ATOM   3410 H  H    . ASN A 1 217 ? -11.35579 -4.50785  -21.60995 1.000 13.79816 ? 1676 ASN A H    1 
ATOM   3411 H  HA   . ASN A 1 217 ? -8.72157  -4.28687  -21.06139 1.000 13.05281 ? 1676 ASN A HA   1 
ATOM   3412 H  HB2  . ASN A 1 217 ? -10.90687 -4.12032  -19.31923 1.000 13.89923 ? 1676 ASN A HB2  1 
ATOM   3413 H  HB3  . ASN A 1 217 ? -9.41418  -4.25108  -18.78990 1.000 13.89923 ? 1676 ASN A HB3  1 
ATOM   3414 H  HD21 . ASN A 1 217 ? -10.84347 -0.86799  -19.93174 1.000 16.44795 ? 1676 ASN A HD21 1 
ATOM   3415 H  HD22 . ASN A 1 217 ? -11.66492 -2.11046  -19.91425 1.000 16.44795 ? 1676 ASN A HD22 1 
ATOM   3416 N  N    . MET A 1 218 ? -9.49057  -6.91722  -21.66055 1.000 10.79605 ? 1677 MET A N    1 
ATOM   3417 C  CA   . MET A 1 218 ? -9.24456  -8.35312  -21.57759 1.000 10.86448 ? 1677 MET A CA   1 
ATOM   3418 C  C    . MET A 1 218 ? -7.91022  -8.67091  -20.93913 1.000 10.36442 ? 1677 MET A C    1 
ATOM   3419 O  O    . MET A 1 218 ? -7.78810  -9.67020  -20.21464 1.000 10.28020 ? 1677 MET A O    1 
ATOM   3420 C  CB   . MET A 1 218 ? -9.32322  -8.95478  -22.96487 1.000 11.72511 ? 1677 MET A CB   1 
ATOM   3421 C  CG   . MET A 1 218 ? -9.28053  -10.46607 -23.06169 1.000 13.11212 ? 1677 MET A CG   1 
ATOM   3422 S  SD   . MET A 1 218 ? -10.48170 -11.38734 -22.08908 1.000 14.08066 ? 1677 MET A SD   1 
ATOM   3423 C  CE   . MET A 1 218 ? -11.97403 -10.82369 -22.91539 1.000 15.07025 ? 1677 MET A CE   1 
ATOM   3424 H  H    . MET A 1 218 ? -9.71163  -6.63958  -22.44391 1.000 12.95806 ? 1677 MET A H    1 
ATOM   3425 H  HA   . MET A 1 218 ? -9.93788  -8.74964  -21.02716 1.000 13.04017 ? 1677 MET A HA   1 
ATOM   3426 H  HB2  . MET A 1 218 ? -10.15815 -8.66953  -23.36788 1.000 14.07293 ? 1677 MET A HB2  1 
ATOM   3427 H  HB3  . MET A 1 218 ? -8.57382  -8.61758  -23.48024 1.000 14.07293 ? 1677 MET A HB3  1 
ATOM   3428 H  HG2  . MET A 1 218 ? -9.42401  -10.71015 -23.98945 1.000 15.73734 ? 1677 MET A HG2  1 
ATOM   3429 H  HG3  . MET A 1 218 ? -8.40190  -10.75917 -22.77359 1.000 15.73734 ? 1677 MET A HG3  1 
ATOM   3430 H  HE1  . MET A 1 218 ? -12.74120 -11.26283 -22.51602 1.000 18.08709 ? 1677 MET A HE1  1 
ATOM   3431 H  HE2  . MET A 1 218 ? -12.05033 -9.86261  -22.80860 1.000 18.08709 ? 1677 MET A HE2  1 
ATOM   3432 H  HE3  . MET A 1 218 ? -11.91752 -11.04838 -23.85732 1.000 18.08709 ? 1677 MET A HE3  1 
ATOM   3433 N  N    . ALA A 1 219 ? -6.88187  -7.86015  -21.21082 1.000 10.83816 ? 1678 ALA A N    1 
ATOM   3434 C  CA   . ALA A 1 219 ? -5.56960  -8.12712  -20.64274 1.000 11.35138 ? 1678 ALA A CA   1 
ATOM   3435 C  C    . ALA A 1 219 ? -5.56735  -8.12333  -19.11871 1.000 11.70932 ? 1678 ALA A C    1 
ATOM   3436 O  O    . ALA A 1 219 ? -4.66993  -8.73557  -18.51240 1.000 13.04369 ? 1678 ALA A O    1 
ATOM   3437 C  CB   . ALA A 1 219 ? -4.57145  -7.07311  -21.12858 1.000 12.65943 ? 1678 ALA A CB   1 
ATOM   3438 H  H    . ALA A 1 219 ? -6.92250  -7.16292  -21.71265 1.000 13.00859 ? 1678 ALA A H    1 
ATOM   3439 H  HA   . ALA A 1 219 ? -5.28950  -9.00512  -20.94534 1.000 13.62446 ? 1678 ALA A HA   1 
ATOM   3440 H  HB1  . ALA A 1 219 ? -3.70188  -7.25939  -20.74122 1.000 15.19411 ? 1678 ALA A HB1  1 
ATOM   3441 H  HB2  . ALA A 1 219 ? -4.51757  -7.11156  -22.09632 1.000 15.19411 ? 1678 ALA A HB2  1 
ATOM   3442 H  HB3  . ALA A 1 219 ? -4.87714  -6.19605  -20.84890 1.000 15.19411 ? 1678 ALA A HB3  1 
ATOM   3443 N  N    . VAL A 1 220 ? -6.53363  -7.45107  -18.48533 1.000 10.27757 ? 1679 VAL A N    1 
ATOM   3444 C  CA   . VAL A 1 220 ? -6.64114  -7.37825  -17.03744 1.000 9.88279  ? 1679 VAL A CA   1 
ATOM   3445 C  C    . VAL A 1 220 ? -7.38281  -8.58104  -16.46005 1.000 8.91951  ? 1679 VAL A C    1 
ATOM   3446 O  O    . VAL A 1 220 ? -7.30055  -8.82507  -15.25247 1.000 10.40126 ? 1679 VAL A O    1 
ATOM   3447 C  CB   . VAL A 1 220 ? -7.39599  -6.07296  -16.66291 1.000 11.02503 ? 1679 VAL A CB   1 
ATOM   3448 C  CG1  . VAL A 1 220 ? -7.52170  -5.87383  -15.15288 1.000 12.79629 ? 1679 VAL A CG1  1 
ATOM   3449 C  CG2  . VAL A 1 220 ? -6.72358  -4.84887  -17.30929 1.000 12.46993 ? 1679 VAL A CG2  1 
ATOM   3450 H  H    . VAL A 1 220 ? -7.15634  -7.01668  -18.88923 1.000 12.33588 ? 1679 VAL A H    1 
ATOM   3451 H  HA   . VAL A 1 220 ? -5.75607  -7.36530  -16.64073 1.000 11.86214 ? 1679 VAL A HA   1 
ATOM   3452 H  HB   . VAL A 1 220 ? -8.29755  -6.15825  -17.01049 1.000 13.23283 ? 1679 VAL A HB   1 
ATOM   3453 H  HG11 . VAL A 1 220 ? -7.83819  -4.97368  -14.97831 1.000 15.35834 ? 1679 VAL A HG11 1 
ATOM   3454 H  HG12 . VAL A 1 220 ? -8.15297  -6.52055  -14.80053 1.000 15.35834 ? 1679 VAL A HG12 1 
ATOM   3455 H  HG13 . VAL A 1 220 ? -6.65189  -6.00380  -14.74371 1.000 15.35834 ? 1679 VAL A HG13 1 
ATOM   3456 H  HG21 . VAL A 1 220 ? -7.15603  -4.04326  -16.98542 1.000 14.96672 ? 1679 VAL A HG21 1 
ATOM   3457 H  HG22 . VAL A 1 220 ? -5.78425  -4.84013  -17.06746 1.000 14.96672 ? 1679 VAL A HG22 1 
ATOM   3458 H  HG23 . VAL A 1 220 ? -6.81651  -4.90963  -18.27291 1.000 14.96672 ? 1679 VAL A HG23 1 
ATOM   3459 N  N    . ILE A 1 221 ? -8.11242  -9.32552  -17.28496 1.000 8.99320  ? 1680 ILE A N    1 
ATOM   3460 C  CA   . ILE A 1 221 ? -8.90479  -10.46274 -16.80962 1.000 9.00110  ? 1680 ILE A CA   1 
ATOM   3461 C  C    . ILE A 1 221 ? -8.02302  -11.70907 -16.73560 1.000 9.06163  ? 1680 ILE A C    1 
ATOM   3462 O  O    . ILE A 1 221 ? -7.51822  -12.17443 -17.76391 1.000 10.27230 ? 1680 ILE A O    1 
ATOM   3463 C  CB   . ILE A 1 221 ? -10.08484 -10.69791 -17.75816 1.000 9.36693  ? 1680 ILE A CB   1 
ATOM   3464 C  CG1  . ILE A 1 221 ? -10.98402 -9.45598  -17.84927 1.000 10.12229 ? 1680 ILE A CG1  1 
ATOM   3465 C  CG2  . ILE A 1 221 ? -10.88152 -11.92584 -17.34492 1.000 9.58275  ? 1680 ILE A CG2  1 
ATOM   3466 C  CD1  . ILE A 1 221 ? -12.09273 -9.60270  -18.89337 1.000 10.90396 ? 1680 ILE A CD1  1 
ATOM   3467 H  H    . ILE A 1 221 ? -8.16787  -9.19385  -18.13301 1.000 10.79464 ? 1680 ILE A H    1 
ATOM   3468 H  HA   . ILE A 1 221 ? -9.22762  -10.27764 -15.91384 1.000 10.80412 ? 1680 ILE A HA   1 
ATOM   3469 H  HB   . ILE A 1 221 ? -9.72110  -10.86124 -18.64243 1.000 11.24312 ? 1680 ILE A HB   1 
ATOM   3470 H  HG12 . ILE A 1 221 ? -11.40176 -9.30478  -16.98699 1.000 12.14954 ? 1680 ILE A HG12 1 
ATOM   3471 H  HG13 . ILE A 1 221 ? -10.44094 -8.69030  -18.09362 1.000 12.14954 ? 1680 ILE A HG13 1 
ATOM   3472 H  HG21 . ILE A 1 221 ? -11.65885 -12.00606 -17.91957 1.000 11.50209 ? 1680 ILE A HG21 1 
ATOM   3473 H  HG22 . ILE A 1 221 ? -10.32033 -12.71176 -17.43600 1.000 11.50209 ? 1680 ILE A HG22 1 
ATOM   3474 H  HG23 . ILE A 1 221 ? -11.16165 -11.82459 -16.42179 1.000 11.50209 ? 1680 ILE A HG23 1 
ATOM   3475 H  HD11 . ILE A 1 221 ? -12.50774 -8.73781  -19.03699 1.000 13.08755 ? 1680 ILE A HD11 1 
ATOM   3476 H  HD12 . ILE A 1 221 ? -11.70542 -9.92544  -19.72206 1.000 13.08755 ? 1680 ILE A HD12 1 
ATOM   3477 H  HD13 . ILE A 1 221 ? -12.75156 -10.23571 -18.56758 1.000 13.08755 ? 1680 ILE A HD13 1 
ATOM   3478 N  N    . ASP A 1 222 ? -7.82899  -12.24719 -15.52596 1.000 8.86687  ? 1681 ASP A N    1 
ATOM   3479 C  CA   . ASP A 1 222 ? -6.98300  -13.43708 -15.39756 1.000 8.84582  ? 1681 ASP A CA   1 
ATOM   3480 C  C    . ASP A 1 222 ? -7.70520  -14.72613 -15.75796 1.000 8.85635  ? 1681 ASP A C    1 
ATOM   3481 O  O    . ASP A 1 222 ? -7.10520  -15.60376 -16.37687 1.000 9.78803  ? 1681 ASP A O    1 
ATOM   3482 C  CB   . ASP A 1 222 ? -6.42274  -13.55337 -13.98764 1.000 9.26166  ? 1681 ASP A CB   1 
ATOM   3483 C  CG   . ASP A 1 222 ? -5.64733  -12.33997 -13.58816 1.000 9.83278  ? 1681 ASP A CG   1 
ATOM   3484 O  OD1  . ASP A 1 222 ? -4.45164  -12.28910 -13.94537 1.000 11.90144 ? 1681 ASP A OD1  1 
ATOM   3485 O  OD2  . ASP A 1 222 ? -6.25432  -11.43171 -12.94858 1.000 10.03806 ? 1681 ASP A OD2  1 
ATOM   3486 H  H    . ASP A 1 222 ? -8.16392  -11.95279 -14.79061 1.000 10.64305 ? 1681 ASP A H    1 
ATOM   3487 H  HA   . ASP A 1 222 ? -6.24680  -13.32336 -16.01884 1.000 10.61778 ? 1681 ASP A HA   1 
ATOM   3488 H  HB2  . ASP A 1 222 ? -7.15557  -13.66376 -13.36180 1.000 11.11679 ? 1681 ASP A HB2  1 
ATOM   3489 H  HB3  . ASP A 1 222 ? -5.82981  -14.31974 -13.94272 1.000 11.11679 ? 1681 ASP A HB3  1 
ATOM   3490 N  N    . CYS A 1 223 ? -8.96954  -14.85899 -15.36678 1.000 8.90898  ? 1682 CYS A N    1 
ATOM   3491 C  CA   . CYS A 1 223 ? -9.72238  -16.09343 -15.56765 1.000 8.82476  ? 1682 CYS A CA   1 
ATOM   3492 C  C    . CYS A 1 223 ? -11.10926 -15.77261 -16.09892 1.000 8.37471  ? 1682 CYS A C    1 
ATOM   3493 O  O    . CYS A 1 223 ? -11.67647 -14.70956 -15.83141 1.000 9.33535  ? 1682 CYS A O    1 
ATOM   3494 C  CB   . CYS A 1 223 ? -9.90520  -16.90597 -14.26325 1.000 9.44326  ? 1682 CYS A CB   1 
ATOM   3495 S  SG   . CYS A 1 223 ? -8.40927  -17.29375 -13.37415 1.000 10.72236 ? 1682 CYS A SG   1 
ATOM   3496 H  H    . CYS A 1 223 ? -9.41965  -14.23857 -14.97682 1.000 10.69358 ? 1682 CYS A H    1 
ATOM   3497 H  HA   . CYS A 1 223 ? -9.23203  -16.62882 -16.21094 1.000 10.59251 ? 1682 CYS A HA   1 
ATOM   3498 H  HB2  . CYS A 1 223 ? -10.47148 -16.39499 -13.66398 1.000 11.33470 ? 1682 CYS A HB2  1 
ATOM   3499 H  HB3  . CYS A 1 223 ? -10.33290 -17.74735 -14.48697 1.000 11.33470 ? 1682 CYS A HB3  1 
ATOM   3500 H  HG   . CYS A 1 223 ? -8.69345  -17.89214 -12.37356 1.000 12.86963 ? 1682 CYS A HG   1 
ATOM   3501 N  N    . PHE A 1 224 ? -11.69444 -16.74745 -16.78352 1.000 8.85898  ? 1683 PHE A N    1 
ATOM   3502 C  CA   . PHE A 1 224 ? -13.14133 -16.80284 -16.94755 1.000 9.33272  ? 1683 PHE A CA   1 
ATOM   3503 C  C    . PHE A 1 224 ? -13.66473 -17.82079 -15.95079 1.000 9.16954  ? 1683 PHE A C    1 
ATOM   3504 O  O    . PHE A 1 224 ? -13.01633 -18.84081 -15.69171 1.000 10.54339 ? 1683 PHE A O    1 
ATOM   3505 C  CB   . PHE A 1 224 ? -13.54164 -17.19819 -18.35727 1.000 9.43010  ? 1683 PHE A CB   1 
ATOM   3506 C  CG   . PHE A 1 224 ? -13.08302 -16.25251 -19.42303 1.000 9.36430  ? 1683 PHE A CG   1 
ATOM   3507 C  CD1  . PHE A 1 224 ? -13.31279 -14.88459 -19.32116 1.000 9.84857  ? 1683 PHE A CD1  1 
ATOM   3508 C  CD2  . PHE A 1 224 ? -12.45816 -16.72624 -20.55209 1.000 9.34588  ? 1683 PHE A CD2  1 
ATOM   3509 C  CE1  . PHE A 1 224 ? -12.91003 -14.02605 -20.32493 1.000 10.12229 ? 1683 PHE A CE1  1 
ATOM   3510 C  CE2  . PHE A 1 224 ? -12.05935 -15.88107 -21.56276 1.000 9.49063  ? 1683 PHE A CE2  1 
ATOM   3511 C  CZ   . PHE A 1 224 ? -12.29770 -14.52297 -21.45476 1.000 10.01701 ? 1683 PHE A CZ   1 
ATOM   3512 H  H    . PHE A 1 224 ? -11.27193 -17.39227 -17.16471 1.000 10.63357 ? 1683 PHE A H    1 
ATOM   3513 H  HA   . PHE A 1 224 ? -13.53698 -15.93199 -16.78637 1.000 11.20206 ? 1683 PHE A HA   1 
ATOM   3514 H  HB2  . PHE A 1 224 ? -13.16009 -18.06802 -18.55405 1.000 11.31891 ? 1683 PHE A HB2  1 
ATOM   3515 H  HB3  . PHE A 1 224 ? -14.50957 -17.24260 -18.40234 1.000 11.31891 ? 1683 PHE A HB3  1 
ATOM   3516 H  HD1  . PHE A 1 224 ? -13.74203 -14.54468 -18.56942 1.000 11.82108 ? 1683 PHE A HD1  1 
ATOM   3517 H  HD2  . PHE A 1 224 ? -12.30118 -17.63913 -20.63506 1.000 11.21785 ? 1683 PHE A HD2  1 
ATOM   3518 H  HE1  . PHE A 1 224 ? -13.05231 -13.11109 -20.23821 1.000 12.14954 ? 1683 PHE A HE1  1 
ATOM   3519 H  HE2  . PHE A 1 224 ? -11.63149 -16.22178 -22.31493 1.000 11.39155 ? 1683 PHE A HE2  1 
ATOM   3520 H  HZ   . PHE A 1 224 ? -12.04598 -13.94818 -22.14116 1.000 12.02321 ? 1683 PHE A HZ   1 
ATOM   3521 N  N    . ALA A 1 225 ? -14.83961 -17.55820 -15.38842 1.000 9.32482  ? 1684 ALA A N    1 
ATOM   3522 C  CA   . ALA A 1 225 ? -15.45069 -18.50327 -14.46529 1.000 9.04058  ? 1684 ALA A CA   1 
ATOM   3523 C  C    . ALA A 1 225 ? -16.94927 -18.26735 -14.52821 1.000 9.51169  ? 1684 ALA A C    1 
ATOM   3524 O  O    . ALA A 1 225 ? -17.38657 -17.12412 -14.59615 1.000 10.41442 ? 1684 ALA A O    1 
ATOM   3525 C  CB   . ALA A 1 225 ? -14.92939 -18.34406 -13.03989 1.000 9.94858  ? 1684 ALA A CB   1 
ATOM   3526 H  H    . ALA A 1 225 ? -15.29855 -16.84391 -15.52540 1.000 11.19258 ? 1684 ALA A H    1 
ATOM   3527 H  HA   . ALA A 1 225 ? -15.25253 -19.41610 -14.72677 1.000 10.85149 ? 1684 ALA A HA   1 
ATOM   3528 H  HB1  . ALA A 1 225 ? -15.36960 -18.99249 -12.46836 1.000 11.94109 ? 1684 ALA A HB1  1 
ATOM   3529 H  HB2  . ALA A 1 225 ? -13.97131 -18.49559 -13.03526 1.000 11.94109 ? 1684 ALA A HB2  1 
ATOM   3530 H  HB3  . ALA A 1 225 ? -15.12361 -17.44525 -12.73115 1.000 11.94109 ? 1684 ALA A HB3  1 
ATOM   3531 N  N    . SER A 1 226 ? -17.74379 -19.33204 -14.51181 1.000 9.34325  ? 1685 SER A N    1 
ATOM   3532 C  CA   . SER A 1 226 ? -19.14649 -19.18380 -14.89293 1.000 9.43010  ? 1685 SER A CA   1 
ATOM   3533 C  C    . SER A 1 226 ? -20.00398 -18.47492 -13.83733 1.000 8.45630  ? 1685 SER A C    1 
ATOM   3534 O  O    . SER A 1 226 ? -21.00103 -17.82916 -14.20456 1.000 9.54853  ? 1685 SER A O    1 
ATOM   3535 C  CB   . SER A 1 226 ? -19.76286 -20.54823 -15.21630 1.000 10.68288 ? 1685 SER A CB   1 
ATOM   3536 O  OG   . SER A 1 226 ? -19.81767 -21.35529 -14.05839 1.000 10.80921 ? 1685 SER A OG   1 
ATOM   3537 H  H    . SER A 1 226 ? -17.50516 -20.12823 -14.29108 1.000 11.21469 ? 1685 SER A H    1 
ATOM   3538 H  HA   . SER A 1 226 ? -19.15887 -18.63222 -15.69074 1.000 11.31892 ? 1685 SER A HA   1 
ATOM   3539 H  HB2  . SER A 1 226 ? -20.66266 -20.41734 -15.55412 1.000 12.82225 ? 1685 SER A HB2  1 
ATOM   3540 H  HB3  . SER A 1 226 ? -19.21832 -20.99121 -15.88574 1.000 12.82225 ? 1685 SER A HB3  1 
ATOM   3541 H  HG   . SER A 1 226 ? -19.04189 -21.49291 -13.76714 1.000 12.97385 ? 1685 SER A HG   1 
ATOM   3542 N  N    . ASP A 1 227 ? -19.70034 -18.61860 -12.55034 1.000 9.15901  ? 1686 ASP A N    1 
ATOM   3543 C  CA   . ASP A 1 227 ? -20.67106 -18.35393 -11.47772 1.000 8.81160  ? 1686 ASP A CA   1 
ATOM   3544 C  C    . ASP A 1 227 ? -21.97775 -19.08860 -11.78276 1.000 8.83792  ? 1686 ASP A C    1 
ATOM   3545 O  O    . ASP A 1 227 ? -23.08182 -18.55756 -11.63168 1.000 9.27482  ? 1686 ASP A O    1 
ATOM   3546 C  CB   . ASP A 1 227 ? -20.92045 -16.86491 -11.22844 1.000 9.13269  ? 1686 ASP A CB   1 
ATOM   3547 C  CG   . ASP A 1 227 ? -21.56032 -16.60398 -9.87355  1.000 9.54854  ? 1686 ASP A CG   1 
ATOM   3548 O  OD1  . ASP A 1 227 ? -21.59223 -17.53149 -9.02512  1.000 10.59866 ? 1686 ASP A OD1  1 
ATOM   3549 O  OD2  . ASP A 1 227 ? -22.02888 -15.45409 -9.67121  1.000 10.35916 ? 1686 ASP A OD2  1 
ATOM   3550 H  H    . ASP A 1 227 ? -18.92988 -18.87138 -12.26382 1.000 10.99361 ? 1686 ASP A H    1 
ATOM   3551 H  HA   . ASP A 1 227 ? -20.29253 -18.69201 -10.65109 1.000 10.57672 ? 1686 ASP A HA   1 
ATOM   3552 H  HB2  . ASP A 1 227 ? -20.07418 -16.39180 -11.25841 1.000 10.96203 ? 1686 ASP A HB2  1 
ATOM   3553 H  HB3  . ASP A 1 227 ? -21.51584 -16.52351 -11.91390 1.000 10.96203 ? 1686 ASP A HB3  1 
ATOM   3554 N  N    . HIS A 1 228 ? -21.84010 -20.35309 -12.17782 1.000 9.45905  ? 1687 HIS A N    1 
ATOM   3555 C  CA   . HIS A 1 228 ? -22.99666 -21.20691 -12.38185 1.000 10.09860 ? 1687 HIS A CA   1 
ATOM   3556 C  C    . HIS A 1 228 ? -23.82218 -21.21396 -11.10919 1.000 10.06438 ? 1687 HIS A C    1 
ATOM   3557 O  O    . HIS A 1 228 ? -23.36517 -21.67681 -10.06641 1.000 10.13281 ? 1687 HIS A O    1 
ATOM   3558 C  CB   . HIS A 1 228 ? -22.45530 -22.61220 -12.65793 1.000 10.13544 ? 1687 HIS A CB   1 
ATOM   3559 C  CG   . HIS A 1 228 ? -23.51415 -23.64292 -12.90831 1.000 9.77751  ? 1687 HIS A CG   1 
ATOM   3560 N  ND1  . HIS A 1 228 ? -24.11304 -23.79498 -14.13622 1.000 10.92501 ? 1687 HIS A ND1  1 
ATOM   3561 C  CD2  . HIS A 1 228 ? -24.05689 -24.57611 -12.09638 1.000 9.58801  ? 1687 HIS A CD2  1 
ATOM   3562 C  CE1  . HIS A 1 228 ? -24.98390 -24.78899 -14.07214 1.000 10.25914 ? 1687 HIS A CE1  1 
ATOM   3563 N  NE2  . HIS A 1 228 ? -24.97893 -25.26184 -12.84138 1.000 10.38284 ? 1687 HIS A NE2  1 
ATOM   3564 H  H    . HIS A 1 228 ? -21.08601 -20.73621 -12.33328 1.000 11.35366 ? 1687 HIS A H    1 
ATOM   3565 H  HA   . HIS A 1 228 ? -23.55212 -20.91086 -13.11989 1.000 12.12112 ? 1687 HIS A HA   1 
ATOM   3566 H  HB2  . HIS A 1 228 ? -21.88816 -22.57677 -13.44405 1.000 12.16533 ? 1687 HIS A HB2  1 
ATOM   3567 H  HB3  . HIS A 1 228 ? -21.93930 -22.90191 -11.88935 1.000 12.16533 ? 1687 HIS A HB3  1 
ATOM   3568 H  HD2  . HIS A 1 228 ? -23.84509 -24.72443 -11.20304 1.000 11.50841 ? 1687 HIS A HD2  1 
ATOM   3569 H  HE1  . HIS A 1 228 ? -25.50879 -25.10033 -14.77390 1.000 12.31377 ? 1687 HIS A HE1  1 
ATOM   3570 H  HE2  . HIS A 1 228 ? -25.47662 -25.90066 -12.55187 1.000 12.46221 ? 1687 HIS A HE2  1 
ATOM   3571 N  N    . ALA A 1 229 ? -25.04876 -20.69545 -11.18631 1.000 10.62235 ? 1688 ALA A N    1 
ATOM   3572 C  CA   . ALA A 1 229 ? -25.84505 -20.38650 -9.99840  1.000 11.00397 ? 1688 ALA A CA   1 
ATOM   3573 C  C    . ALA A 1 229 ? -27.26638 -20.82049 -10.30952 1.000 10.76973 ? 1688 ALA A C    1 
ATOM   3574 O  O    . ALA A 1 229 ? -28.16695 -20.00511 -10.56439 1.000 11.39086 ? 1688 ALA A O    1 
ATOM   3575 C  CB   . ALA A 1 229 ? -25.73545 -18.91293 -9.62170  1.000 10.92765 ? 1688 ALA A CB   1 
ATOM   3576 H  H    . ALA A 1 229 ? -25.44620 -20.51146 -11.92645 1.000 12.74961 ? 1688 ALA A H    1 
ATOM   3577 H  HA   . ALA A 1 229 ? -25.52832 -20.88100 -9.22636  1.000 13.20756 ? 1688 ALA A HA   1 
ATOM   3578 H  HB1  . ALA A 1 229 ? -26.29366 -18.74268 -8.84689  1.000 13.11597 ? 1688 ALA A HB1  1 
ATOM   3579 H  HB2  . ALA A 1 229 ? -24.81031 -18.70795 -9.41433  1.000 13.11597 ? 1688 ALA A HB2  1 
ATOM   3580 H  HB3  . ALA A 1 229 ? -26.03428 -18.37265 -10.36982 1.000 13.11597 ? 1688 ALA A HB3  1 
ATOM   3581 N  N    . PRO A 1 230 ? -27.48905 -22.12604 -10.36437 1.000 11.00660 ? 1689 PRO A N    1 
ATOM   3582 C  CA   . PRO A 1 230 ? -28.76750 -22.63968 -10.84583 1.000 10.53286 ? 1689 PRO A CA   1 
ATOM   3583 C  C    . PRO A 1 230 ? -29.87500 -22.49018 -9.82279  1.000 10.78816 ? 1689 PRO A C    1 
ATOM   3584 O  O    . PRO A 1 230 ? -29.69313 -22.68165 -8.62196  1.000 11.14346 ? 1689 PRO A O    1 
ATOM   3585 C  CB   . PRO A 1 230 ? -28.46512 -24.12073 -11.11142 1.000 11.02239 ? 1689 PRO A CB   1 
ATOM   3586 C  CG   . PRO A 1 230 ? -27.35746 -24.46413 -10.11058 1.000 11.73827 ? 1689 PRO A CG   1 
ATOM   3587 C  CD   . PRO A 1 230 ? -26.51160 -23.19158 -10.06270 1.000 11.52772 ? 1689 PRO A CD   1 
ATOM   3588 H  HA   . PRO A 1 230 ? -29.02658 -22.19136 -11.66607 1.000 12.64223 ? 1689 PRO A HA   1 
ATOM   3589 H  HB2  . PRO A 1 230 ? -29.25816 -24.65640 -10.95315 1.000 13.22967 ? 1689 PRO A HB2  1 
ATOM   3590 H  HB3  . PRO A 1 230 ? -28.16090 -24.24021 -12.02470 1.000 13.22967 ? 1689 PRO A HB3  1 
ATOM   3591 H  HG2  . PRO A 1 230 ? -27.73936 -24.66584 -9.24203  1.000 14.08872 ? 1689 PRO A HG2  1 
ATOM   3592 H  HG3  . PRO A 1 230 ? -26.83894 -25.21971 -10.42858 1.000 14.08872 ? 1689 PRO A HG3  1 
ATOM   3593 H  HD2  . PRO A 1 230 ? -26.12476 -23.06656 -9.18201  1.000 13.83606 ? 1689 PRO A HD2  1 
ATOM   3594 H  HD3  . PRO A 1 230 ? -25.81042 -23.21717 -10.73247 1.000 13.83606 ? 1689 PRO A HD3  1 
ATOM   3595 N  N    . HIS A 1 231 ? -31.04224 -22.14162 -10.35133 1.000 10.90396 ? 1690 HIS A N    1 
ATOM   3596 C  CA   . HIS A 1 231 ? -32.30862 -22.07953 -9.64881  1.000 11.24874 ? 1690 HIS A CA   1 
ATOM   3597 C  C    . HIS A 1 231 ? -33.34005 -22.53073 -10.67353 1.000 11.18557 ? 1690 HIS A C    1 
ATOM   3598 O  O    . HIS A 1 231 ? -33.11885 -22.38483 -11.87749 1.000 11.94619 ? 1690 HIS A O    1 
ATOM   3599 C  CB   . HIS A 1 231 ? -32.67698 -20.65577 -9.21262  1.000 11.25137 ? 1690 HIS A CB   1 
ATOM   3600 C  CG   . HIS A 1 231 ? -31.67048 -20.00612 -8.32441  1.000 11.36717 ? 1690 HIS A CG   1 
ATOM   3601 N  ND1  . HIS A 1 231 ? -31.54342 -20.33211 -6.99295  1.000 11.39612 ? 1690 HIS A ND1  1 
ATOM   3602 C  CD2  . HIS A 1 231 ? -30.77974 -19.00966 -8.56032  1.000 12.33571 ? 1690 HIS A CD2  1 
ATOM   3603 C  CE1  . HIS A 1 231 ? -30.61302 -19.56875 -6.44530  1.000 12.35150 ? 1690 HIS A CE1  1 
ATOM   3604 N  NE2  . HIS A 1 231 ? -30.13482 -18.75802 -7.37738  1.000 12.66206 ? 1690 HIS A NE2  1 
ATOM   3605 H  H    . HIS A 1 231 ? -31.12920 -21.92066 -11.17790 1.000 13.08755 ? 1690 HIS A H    1 
ATOM   3606 H  HA   . HIS A 1 231 ? -32.29164 -22.63352 -8.85275  1.000 13.50128 ? 1690 HIS A HA   1 
ATOM   3607 H  HB2  . HIS A 1 231 ? -32.76978 -20.10343 -10.00458 1.000 13.50444 ? 1690 HIS A HB2  1 
ATOM   3608 H  HB3  . HIS A 1 231 ? -33.51771 -20.68747 -8.72986  1.000 13.50444 ? 1690 HIS A HB3  1 
ATOM   3609 H  HD2  . HIS A 1 231 ? -30.63439 -18.57885 -9.37161  1.000 14.80565 ? 1690 HIS A HD2  1 
ATOM   3610 H  HE1  . HIS A 1 231 ? -30.34058 -19.59633 -5.55653  1.000 14.82460 ? 1690 HIS A HE1  1 
ATOM   3611 H  HE2  . HIS A 1 231 ? -29.51931 -18.16910 -7.25937  1.000 15.19727 ? 1690 HIS A HE2  1 
ATOM   3612 N  N    . THR A 1 232 ? -34.47071 -23.07825 -10.22013 1.000 11.99883 ? 1691 THR A N    1 
ATOM   3613 C  CA   . THR A 1 232 ? -35.45986 -23.51642 -11.18486 1.000 12.99631 ? 1691 THR A CA   1 
ATOM   3614 C  C    . THR A 1 232 ? -36.17992 -22.31082 -11.77573 1.000 12.35940 ? 1691 THR A C    1 
ATOM   3615 O  O    . THR A 1 232 ? -36.18296 -21.21492 -11.20937 1.000 12.66996 ? 1691 THR A O    1 
ATOM   3616 C  CB   . THR A 1 232 ? -36.47476 -24.45501 -10.53908 1.000 14.36227 ? 1691 THR A CB   1 
ATOM   3617 O  OG1  . THR A 1 232 ? -37.25031 -23.69426 -9.61076  1.000 14.42017 ? 1691 THR A OG1  1 
ATOM   3618 C  CG2  . THR A 1 232 ? -35.81227 -25.61080 -9.82120  1.000 15.57557 ? 1691 THR A CG2  1 
ATOM   3619 H  H    . THR A 1 232 ? -34.67337 -23.19874 -9.39308  1.000 14.40139 ? 1691 THR A H    1 
ATOM   3620 H  HA   . THR A 1 232 ? -35.01877 -24.00273 -11.89890 1.000 15.59837 ? 1691 THR A HA   1 
ATOM   3621 H  HB   . THR A 1 232 ? -37.03824 -24.84474 -11.22573 1.000 17.23752 ? 1691 THR A HB   1 
ATOM   3622 H  HG1  . THR A 1 232 ? -37.82150 -24.18732 -9.24166  1.000 17.30700 ? 1691 THR A HG1  1 
ATOM   3623 H  HG21 . THR A 1 232 ? -36.48594 -26.22155 -9.48347  1.000 18.69348 ? 1691 THR A HG21 1 
ATOM   3624 H  HG22 . THR A 1 232 ? -35.23006 -26.09030 -10.43112 1.000 18.69348 ? 1691 THR A HG22 1 
ATOM   3625 H  HG23 . THR A 1 232 ? -35.28512 -25.28071 -9.07686  1.000 18.69348 ? 1691 THR A HG23 1 
ATOM   3626 N  N    . LEU A 1 233 ? -36.83430 -22.54568 -12.91496 1.000 12.54363 ? 1692 LEU A N    1 
ATOM   3627 C  CA   . LEU A 1 233 ? -37.61270 -21.49261 -13.54721 1.000 12.87525 ? 1692 LEU A CA   1 
ATOM   3628 C  C    . LEU A 1 233 ? -38.71042 -20.99151 -12.61456 1.000 13.37004 ? 1692 LEU A C    1 
ATOM   3629 O  O    . LEU A 1 233 ? -38.95840 -19.77970 -12.53006 1.000 13.62534 ? 1692 LEU A O    1 
ATOM   3630 C  CB   . LEU A 1 233 ? -38.20216 -21.99022 -14.86780 1.000 13.76220 ? 1692 LEU A CB   1 
ATOM   3631 C  CG   . LEU A 1 233 ? -38.91418 -20.91240 -15.68184 1.000 14.87549 ? 1692 LEU A CG   1 
ATOM   3632 C  CD1  . LEU A 1 233 ? -37.97077 -19.83525 -16.18952 1.000 15.46503 ? 1692 LEU A CD1  1 
ATOM   3633 C  CD2  . LEU A 1 233 ? -39.66779 -21.53935 -16.84089 1.000 15.36765 ? 1692 LEU A CD2  1 
ATOM   3634 H  H    . LEU A 1 233 ? -36.84127 -23.29700 -13.33336 1.000 15.05515 ? 1692 LEU A H    1 
ATOM   3635 H  HA   . LEU A 1 233 ? -37.02766 -20.74622 -13.75099 1.000 15.45310 ? 1692 LEU A HA   1 
ATOM   3636 H  HB2  . LEU A 1 233 ? -37.48285 -22.34476 -15.41350 1.000 16.51743 ? 1692 LEU A HB2  1 
ATOM   3637 H  HB3  . LEU A 1 233 ? -38.84736 -22.68838 -14.67495 1.000 16.51743 ? 1692 LEU A HB3  1 
ATOM   3638 H  HG   . LEU A 1 233 ? -39.54405 -20.47132 -15.09055 1.000 17.85338 ? 1692 LEU A HG   1 
ATOM   3639 H  HD11 . LEU A 1 233 ? -38.46172 -19.23403 -16.77124 1.000 18.56083 ? 1692 LEU A HD11 1 
ATOM   3640 H  HD12 . LEU A 1 233 ? -37.61433 -19.34508 -15.43218 1.000 18.56083 ? 1692 LEU A HD12 1 
ATOM   3641 H  HD13 . LEU A 1 233 ? -37.24794 -20.25493 -16.68175 1.000 18.56083 ? 1692 LEU A HD13 1 
ATOM   3642 H  HD21 . LEU A 1 233 ? -40.12613 -20.84114 -17.33417 1.000 18.44398 ? 1692 LEU A HD21 1 
ATOM   3643 H  HD22 . LEU A 1 233 ? -39.03568 -21.99312 -17.42006 1.000 18.44398 ? 1692 LEU A HD22 1 
ATOM   3644 H  HD23 . LEU A 1 233 ? -40.31191 -22.17509 -16.49182 1.000 18.44398 ? 1692 LEU A HD23 1 
ATOM   3645 N  N    . GLU A 1 234 ? -39.39150 -21.91096 -11.91192 1.000 13.45953 ? 1693 GLU A N    1 
ATOM   3646 C  CA   . GLU A 1 234 ? -40.40571 -21.51063 -10.93891 1.000 14.48860 ? 1693 GLU A CA   1 
ATOM   3647 C  C    . GLU A 1 234 ? -39.83535 -20.53644 -9.92313  1.000 13.81747 ? 1693 GLU A C    1 
ATOM   3648 O  O    . GLU A 1 234 ? -40.48160 -19.54699 -9.56807  1.000 13.73851 ? 1693 GLU A O    1 
ATOM   3649 C  CB   . GLU A 1 234 ? -41.00536 -22.75522 -10.25886 1.000 16.45199 ? 1693 GLU A CB   1 
ATOM   3650 C  CG   . GLU A 1 234 ? -42.10511 -22.47311 -9.23126  1.000 19.71291 ? 1693 GLU A CG   1 
ATOM   3651 C  CD   . GLU A 1 234 ? -41.59701 -22.11084 -7.83215  1.000 22.20795 ? 1693 GLU A CD   1 
ATOM   3652 O  OE1  . GLU A 1 234 ? -40.64559 -22.76340 -7.34423  1.000 22.70537 ? 1693 GLU A OE1  1 
ATOM   3653 O  OE2  . GLU A 1 234 ? -42.18857 -21.21296 -7.17909  1.000 23.93973 ? 1693 GLU A OE2  1 
ATOM   3654 H  H    . GLU A 1 234 ? -39.28326 -22.76121 -11.98232 1.000 16.15423 ? 1693 GLU A H    1 
ATOM   3655 H  HA   . GLU A 1 234 ? -41.13089 -21.05855 -11.39787 1.000 17.38912 ? 1693 GLU A HA   1 
ATOM   3656 H  HB2  . GLU A 1 234 ? -41.38896 -23.32365 -10.94490 1.000 19.74519 ? 1693 GLU A HB2  1 
ATOM   3657 H  HB3  . GLU A 1 234 ? -40.29269 -23.22550 -9.79861  1.000 19.74519 ? 1693 GLU A HB3  1 
ATOM   3658 H  HG2  . GLU A 1 234 ? -42.64046 -21.72912 -9.54870  1.000 23.65829 ? 1693 GLU A HG2  1 
ATOM   3659 H  HG3  . GLU A 1 234 ? -42.65718 -23.26597 -9.14470  1.000 23.65829 ? 1693 GLU A HG3  1 
ATOM   3660 N  N    . GLU A 1 235 ? -38.62549 -20.80473 -9.43225  1.000 12.56995 ? 1694 GLU A N    1 
ATOM   3661 C  CA   . GLU A 1 235 ? -38.01735 -19.91640 -8.45034  1.000 12.44888 ? 1694 GLU A CA   1 
ATOM   3662 C  C    . GLU A 1 235 ? -37.67132 -18.57822 -9.09021  1.000 12.49099 ? 1694 GLU A C    1 
ATOM   3663 O  O    . GLU A 1 235 ? -37.93211 -17.50884 -8.51486  1.000 13.24634 ? 1694 GLU A O    1 
ATOM   3664 C  CB   . GLU A 1 235 ? -36.78449 -20.59878 -7.86370  1.000 12.52521 ? 1694 GLU A CB   1 
ATOM   3665 C  CG   . GLU A 1 235 ? -37.14096 -21.75923 -6.94868  1.000 13.25687 ? 1694 GLU A CG   1 
ATOM   3666 C  CD   . GLU A 1 235 ? -35.94253 -22.59464 -6.51011  1.000 14.48333 ? 1694 GLU A CD   1 
ATOM   3667 O  OE1  . GLU A 1 235 ? -34.95833 -22.73129 -7.29386  1.000 14.28594 ? 1694 GLU A OE1  1 
ATOM   3668 O  OE2  . GLU A 1 235 ? -36.01714 -23.13120 -5.37342  1.000 15.80718 ? 1694 GLU A OE2  1 
ATOM   3669 H  H    . GLU A 1 235 ? -38.14492 -21.48422 -9.64892  1.000 15.08674 ? 1694 GLU A H    1 
ATOM   3670 H  HA   . GLU A 1 235 ? -38.63451 -19.74056 -7.72295  1.000 14.94145 ? 1694 GLU A HA   1 
ATOM   3671 H  HB2  . GLU A 1 235 ? -36.23843 -20.94276 -8.58785  1.000 15.03305 ? 1694 GLU A HB2  1 
ATOM   3672 H  HB3  . GLU A 1 235 ? -36.28023 -19.95124 -7.34666  1.000 15.03305 ? 1694 GLU A HB3  1 
ATOM   3673 H  HG2  . GLU A 1 235 ? -37.56294 -21.40712 -6.14940  1.000 15.91104 ? 1694 GLU A HG2  1 
ATOM   3674 H  HG3  . GLU A 1 235 ? -37.75462 -22.34717 -7.41627  1.000 15.91104 ? 1694 GLU A HG3  1 
ATOM   3675 N  N    . LYS A 1 236 ? -37.08079 -18.61452 -10.28895 1.000 12.63311 ? 1695 LYS A N    1 
ATOM   3676 C  CA   . LYS A 1 236 ? -36.67022 -17.37486 -10.93954 1.000 12.58574 ? 1695 LYS A CA   1 
ATOM   3677 C  C    . LYS A 1 236 ? -37.86126 -16.48544 -11.26185 1.000 13.83326 ? 1695 LYS A C    1 
ATOM   3678 O  O    . LYS A 1 236 ? -37.71447 -15.26773 -11.34390 1.000 14.73863 ? 1695 LYS A O    1 
ATOM   3679 C  CB   . LYS A 1 236 ? -35.93167 -17.64783 -12.24574 1.000 12.63838 ? 1695 LYS A CB   1 
ATOM   3680 C  CG   . LYS A 1 236 ? -34.56421 -18.33888 -12.11221 1.000 12.75681 ? 1695 LYS A CG   1 
ATOM   3681 C  CD   . LYS A 1 236 ? -33.56159 -17.52199 -11.28866 1.000 12.70417 ? 1695 LYS A CD   1 
ATOM   3682 C  CE   . LYS A 1 236 ? -33.28743 -16.15288 -11.89284 1.000 12.25939 ? 1695 LYS A CE   1 
ATOM   3683 N  NZ   . LYS A 1 236 ? -32.09066 -15.53549 -11.26267 1.000 12.47257 ? 1695 LYS A NZ   1 
ATOM   3684 H  H    . LYS A 1 236 ? -36.91121 -19.32992 -10.73509 1.000 15.16253 ? 1695 LYS A H    1 
ATOM   3685 H  HA   . LYS A 1 236 ? -36.07055 -16.92255 -10.32577 1.000 15.10569 ? 1695 LYS A HA   1 
ATOM   3686 H  HB2  . LYS A 1 236 ? -36.48957 -18.21944 -12.79611 1.000 15.16885 ? 1695 LYS A HB2  1 
ATOM   3687 H  HB3  . LYS A 1 236 ? -35.78237 -16.80007 -12.69286 1.000 15.16885 ? 1695 LYS A HB3  1 
ATOM   3688 H  HG2  . LYS A 1 236 ? -34.68445 -19.19535 -11.67300 1.000 15.31097 ? 1695 LYS A HG2  1 
ATOM   3689 H  HG3  . LYS A 1 236 ? -34.18839 -18.46956 -12.99685 1.000 15.31097 ? 1695 LYS A HG3  1 
ATOM   3690 H  HD2  . LYS A 1 236 ? -33.91711 -17.39046 -10.39580 1.000 15.24781 ? 1695 LYS A HD2  1 
ATOM   3691 H  HD3  . LYS A 1 236 ? -32.72104 -18.00399 -11.24338 1.000 15.24781 ? 1695 LYS A HD3  1 
ATOM   3692 H  HE2  . LYS A 1 236 ? -33.12312 -16.24468 -12.84440 1.000 14.71406 ? 1695 LYS A HE2  1 
ATOM   3693 H  HE3  . LYS A 1 236 ? -34.05009 -15.57272 -11.74232 1.000 14.71406 ? 1695 LYS A HE3  1 
ATOM   3694 H  HZ1  . LYS A 1 236 ? -32.22299 -15.43881 -10.38788 1.000 14.96988 ? 1695 LYS A HZ1  1 
ATOM   3695 H  HZ2  . LYS A 1 236 ? -31.37786 -16.05260 -11.39155 1.000 14.96988 ? 1695 LYS A HZ2  1 
ATOM   3696 H  HZ3  . LYS A 1 236 ? -31.93607 -14.73584 -11.62151 1.000 14.96988 ? 1695 LYS A HZ3  1 
ATOM   3697 N  N    . CYS A 1 237 ? -39.04911 -17.06790 -11.44970 1.000 14.16751 ? 1696 CYS A N    1 
ATOM   3698 C  CA   . CYS A 1 237 ? -40.19912 -16.31770 -11.95462 1.000 14.58598 ? 1696 CYS A CA   1 
ATOM   3699 C  C    . CYS A 1 237 ? -41.27458 -16.14268 -10.88408 1.000 15.34397 ? 1696 CYS A C    1 
ATOM   3700 O  O    . CYS A 1 237 ? -42.36183 -15.62131 -11.17815 1.000 15.62031 ? 1696 CYS A O    1 
ATOM   3701 C  CB   . CYS A 1 237 ? -40.77036 -17.04712 -13.17373 1.000 16.19933 ? 1696 CYS A CB   1 
ATOM   3702 S  SG   . CYS A 1 237 ? -39.61248 -17.05493 -14.52924 1.000 18.78385 ? 1696 CYS A SG   1 
ATOM   3703 H  H    . CYS A 1 237 ? -39.21196 -17.89733 -11.29119 1.000 17.00381 ? 1696 CYS A H    1 
ATOM   3704 H  HA   . CYS A 1 237 ? -39.91953 -15.43198 -12.23431 1.000 17.50598 ? 1696 CYS A HA   1 
ATOM   3705 H  HB2  . CYS A 1 237 ? -40.96754 -17.96618 -12.93426 1.000 19.44199 ? 1696 CYS A HB2  1 
ATOM   3706 H  HB3  . CYS A 1 237 ? -41.57989 -16.59924 -13.46521 1.000 19.44199 ? 1696 CYS A HB3  1 
ATOM   3707 H  HG   . CYS A 1 237 ? -40.11479 -17.60687 -15.46895 1.000 22.54341 ? 1696 CYS A HG   1 
ATOM   3708 N  N    . GLY A 1 238 ? -40.98546 -16.53876 -9.64925  1.000 15.95456 ? 1697 GLY A N    1 
ATOM   3709 C  CA   . GLY A 1 238 ? -41.92137 -16.44667 -8.54817  1.000 16.55464 ? 1697 GLY A CA   1 
ATOM   3710 C  C    . GLY A 1 238 ? -41.81614 -15.14783 -7.79332  1.000 17.99692 ? 1697 GLY A C    1 
ATOM   3711 O  O    . GLY A 1 238 ? -41.29416 -14.14515 -8.29173  1.000 18.98387 ? 1697 GLY A O    1 
ATOM   3712 H  H    . GLY A 1 238 ? -40.22707 -16.87467 -9.42207  1.000 19.14828 ? 1697 GLY A H    1 
ATOM   3713 H  HA2  . GLY A 1 238 ? -42.82535 -16.52559 -8.89093  1.000 19.86836 ? 1697 GLY A HA2  1 
ATOM   3714 H  HA3  . GLY A 1 238 ? -41.75473 -17.17265 -7.92680  1.000 19.86836 ? 1697 GLY A HA3  1 
ATOM   3715 N  N    . SER A 1 239 ? -42.34686 -15.16329 -6.56311  1.000 19.66554 ? 1698 SER A N    1 
ATOM   3716 C  CA   . SER A 1 239 ? -42.56768 -13.92112 -5.84005  1.000 22.87381 ? 1698 SER A CA   1 
ATOM   3717 C  C    . SER A 1 239 ? -41.29477 -13.30058 -5.28716  1.000 23.73708 ? 1698 SER A C    1 
ATOM   3718 O  O    . SER A 1 239 ? -41.28507 -12.09371 -5.03360  1.000 25.23725 ? 1698 SER A O    1 
ATOM   3719 C  CB   . SER A 1 239 ? -43.58592 -14.10989 -4.71048  1.000 25.02670 ? 1698 SER A CB   1 
ATOM   3720 O  OG   . SER A 1 239 ? -43.07955 -15.02226 -3.75085  1.000 27.05852 ? 1698 SER A OG   1 
ATOM   3721 H  H    . SER A 1 239 ? -42.58173 -15.87271 -6.13748  1.000 23.60144 ? 1698 SER A H    1 
ATOM   3722 H  HA   . SER A 1 239 ? -42.94427 -13.29092 -6.47403  1.000 27.45137 ? 1698 SER A HA   1 
ATOM   3723 H  HB2  . SER A 1 239 ? -43.75053 -13.25503 -4.28269  1.000 30.03484 ? 1698 SER A HB2  1 
ATOM   3724 H  HB3  . SER A 1 239 ? -44.41148 -14.46041 -5.07994  1.000 30.03484 ? 1698 SER A HB3  1 
ATOM   3725 H  HG   . SER A 1 239 ? -43.63629 -15.12496 -3.13030  1.000 32.47303 ? 1698 SER A HG   1 
ATOM   3726 N  N    . ARG A 1 240 ? -40.22416 -14.06668 -5.08566  1.000 22.33691 ? 1699 ARG A N    1 
ATOM   3727 C  CA   . ARG A 1 240 ? -38.95115 -13.50384 -4.61557  1.000 22.36586 ? 1699 ARG A CA   1 
ATOM   3728 C  C    . ARG A 1 240 ? -37.79987 -14.13896 -5.37468  1.000 20.47879 ? 1699 ARG A C    1 
ATOM   3729 O  O    . ARG A 1 240 ? -37.09127 -15.01051 -4.85642  1.000 20.88147 ? 1699 ARG A O    1 
ATOM   3730 C  CB   . ARG A 1 240 ? -38.77569 -13.71408 -3.10772  1.000 23.50284 ? 1699 ARG A CB   1 
ATOM   3731 H  H    . ARG A 1 240 ? -40.20698 -14.91695 -5.21349  1.000 26.80709 ? 1699 ARG A H    1 
ATOM   3732 H  HA   . ARG A 1 240 ? -38.95133 -12.55260 -4.80545  1.000 26.84183 ? 1699 ARG A HA   1 
ATOM   3733 N  N    . PRO A 1 241 ? -37.58073 -13.69836 -6.61249  1.000 19.21285 ? 1700 PRO A N    1 
ATOM   3734 C  CA   . PRO A 1 241 ? -36.62189 -14.39433 -7.46955  1.000 17.91270 ? 1700 PRO A CA   1 
ATOM   3735 C  C    . PRO A 1 241 ? -35.22394 -14.36067 -6.87078  1.000 16.48884 ? 1700 PRO A C    1 
ATOM   3736 O  O    . PRO A 1 241 ? -34.72617 -13.28695 -6.51088  1.000 17.64687 ? 1700 PRO A O    1 
ATOM   3737 C  CB   . PRO A 1 241 ? -36.69523 -13.56544 -8.77053  1.000 19.56552 ? 1700 PRO A CB   1 
ATOM   3738 C  CG   . PRO A 1 241 ? -38.15896 -13.18054 -8.84968  1.000 21.16308 ? 1700 PRO A CG   1 
ATOM   3739 C  CD   . PRO A 1 241 ? -38.53779 -12.79685 -7.40914  1.000 20.20771 ? 1700 PRO A CD   1 
ATOM   3740 H  HA   . PRO A 1 241 ? -36.88215 -15.31486 -7.63017  1.000 21.49803 ? 1700 PRO A HA   1 
ATOM   3741 H  HB2  . PRO A 1 241 ? -36.12626 -12.78258 -8.70494  1.000 23.48142 ? 1700 PRO A HB2  1 
ATOM   3742 H  HB3  . PRO A 1 241 ? -36.42956 -14.10588 -9.53095  1.000 23.48142 ? 1700 PRO A HB3  1 
ATOM   3743 H  HG2  . PRO A 1 241 ? -38.27257 -12.42838 -9.45155  1.000 25.39849 ? 1700 PRO A HG2  1 
ATOM   3744 H  HG3  . PRO A 1 241 ? -38.68458 -13.93498 -9.15862  1.000 25.39849 ? 1700 PRO A HG3  1 
ATOM   3745 H  HD2  . PRO A 1 241 ? -38.36794 -11.85775 -7.23554  1.000 24.25204 ? 1700 PRO A HD2  1 
ATOM   3746 H  HD3  . PRO A 1 241 ? -39.46523 -13.00712 -7.21797  1.000 24.25204 ? 1700 PRO A HD3  1 
ATOM   3747 N  N    . PRO A 1 242 ? -34.58406 -15.51685 -6.71633  1.000 14.49913 ? 1701 PRO A N    1 
ATOM   3748 C  CA   . PRO A 1 242 ? -33.19679 -15.53978 -6.24012  1.000 13.75430 ? 1701 PRO A CA   1 
ATOM   3749 C  C    . PRO A 1 242 ? -32.27069 -15.15072 -7.36941  1.000 13.28846 ? 1701 PRO A C    1 
ATOM   3750 O  O    . PRO A 1 242 ? -32.58311 -15.38588 -8.54156  1.000 13.31477 ? 1701 PRO A O    1 
ATOM   3751 C  CB   . PRO A 1 242 ? -32.97778 -17.00692 -5.84366  1.000 14.64651 ? 1701 PRO A CB   1 
ATOM   3752 C  CG   . PRO A 1 242 ? -33.91116 -17.75487 -6.66230  1.000 15.58347 ? 1701 PRO A CG   1 
ATOM   3753 C  CD   . PRO A 1 242 ? -35.11449 -16.87609 -6.91233  1.000 14.87549 ? 1701 PRO A CD   1 
ATOM   3754 H  HA   . PRO A 1 242 ? -33.07153 -14.96743 -5.46706  1.000 16.50796 ? 1701 PRO A HA   1 
ATOM   3755 H  HB2  . PRO A 1 242 ? -32.06283 -17.26777 -6.03262  1.000 17.57861 ? 1701 PRO A HB2  1 
ATOM   3756 H  HB3  . PRO A 1 242 ? -33.16888 -17.12688 -4.90027  1.000 17.57861 ? 1701 PRO A HB3  1 
ATOM   3757 H  HG2  . PRO A 1 242 ? -33.48420 -17.98714 -7.50173  1.000 18.70296 ? 1701 PRO A HG2  1 
ATOM   3758 H  HG3  . PRO A 1 242 ? -34.17515 -18.56017 -6.19039  1.000 18.70296 ? 1701 PRO A HG3  1 
ATOM   3759 H  HD2  . PRO A 1 242 ? -35.44455 -16.99119 -7.81715  1.000 17.85338 ? 1701 PRO A HD2  1 
ATOM   3760 H  HD3  . PRO A 1 242 ? -35.82031 -17.06694 -6.27492  1.000 17.85338 ? 1701 PRO A HD3  1 
ATOM   3761 N  N    . PRO A 1 243 ? -31.12323 -14.56041 -7.06495  1.000 13.74904 ? 1702 PRO A N    1 
ATOM   3762 C  CA   . PRO A 1 243 ? -30.19586 -14.16420 -8.13069  1.000 12.88578 ? 1702 PRO A CA   1 
ATOM   3763 C  C    . PRO A 1 243 ? -29.38193 -15.33531 -8.63916  1.000 11.44350 ? 1702 PRO A C    1 
ATOM   3764 O  O    . PRO A 1 243 ? -28.99686 -16.23161 -7.88035  1.000 12.89893 ? 1702 PRO A O    1 
ATOM   3765 C  CB   . PRO A 1 243 ? -29.28858 -13.14719 -7.44048  1.000 13.37794 ? 1702 PRO A CB   1 
ATOM   3766 C  CG   . PRO A 1 243 ? -29.25785 -13.62110 -6.01125  1.000 14.30436 ? 1702 PRO A CG   1 
ATOM   3767 C  CD   . PRO A 1 243 ? -30.63289 -14.20996 -5.72562  1.000 14.30436 ? 1702 PRO A CD   1 
ATOM   3768 H  HA   . PRO A 1 243 ? -30.67299 -13.74759 -8.86532  1.000 15.46573 ? 1702 PRO A HA   1 
ATOM   3769 H  HB2  . PRO A 1 243 ? -28.40326 -13.16243 -7.83656  1.000 16.05632 ? 1702 PRO A HB2  1 
ATOM   3770 H  HB3  . PRO A 1 243 ? -29.66744 -12.25688 -7.50911  1.000 16.05632 ? 1702 PRO A HB3  1 
ATOM   3771 H  HG2  . PRO A 1 243 ? -28.56878 -14.29581 -5.90712  1.000 17.16803 ? 1702 PRO A HG2  1 
ATOM   3772 H  HG3  . PRO A 1 243 ? -29.07872 -12.87049 -5.42354  1.000 17.16803 ? 1702 PRO A HG3  1 
ATOM   3773 H  HD2  . PRO A 1 243 ? -30.56293 -14.99818 -5.16462  1.000 17.16803 ? 1702 PRO A HD2  1 
ATOM   3774 H  HD3  . PRO A 1 243 ? -31.21070 -13.55388 -5.30538  1.000 17.16803 ? 1702 PRO A HD3  1 
ATOM   3775 N  N    . GLY A 1 244 ? -29.09568 -15.30128 -9.93489  1.000 10.45654 ? 1703 GLY A N    1 
ATOM   3776 C  CA   . GLY A 1 244 ? -28.15772 -16.25484 -10.49909 1.000 10.37232 ? 1703 GLY A CA   1 
ATOM   3777 C  C    . GLY A 1 244 ? -28.60286 -16.86535 -11.80059 1.000 10.63287 ? 1703 GLY A C    1 
ATOM   3778 O  O    . GLY A 1 244 ? -29.79938 -17.05410 -12.05088 1.000 10.87238 ? 1703 GLY A O    1 
ATOM   3779 H  H    . GLY A 1 244 ? -29.42825 -14.74249 -10.49770 1.000 12.55064 ? 1703 GLY A H    1 
ATOM   3780 H  HA2  . GLY A 1 244 ? -27.31111 -15.80772 -10.65474 1.000 12.44958 ? 1703 GLY A HA2  1 
ATOM   3781 H  HA3  . GLY A 1 244 ? -28.02230 -16.97525 -9.86382  1.000 12.44958 ? 1703 GLY A HA3  1 
ATOM   3782 N  N    . PHE A 1 245 ? -27.62984 -17.21577 -12.62973 1.000 10.43811 ? 1704 PHE A N    1 
ATOM   3783 C  CA   . PHE A 1 245 ? -27.83183 -17.87380 -13.88322 1.000 10.20387 ? 1704 PHE A CA   1 
ATOM   3784 C  C    . PHE A 1 245 ? -27.08697 -19.20671 -13.90916 1.000 10.03280 ? 1704 PHE A C    1 
ATOM   3785 O  O    . PHE A 1 245 ? -25.91162 -19.25686 -13.50064 1.000 10.61445 ? 1704 PHE A O    1 
ATOM   3786 C  CB   . PHE A 1 245 ? -27.23773 -17.08979 -15.06360 1.000 10.90396 ? 1704 PHE A CB   1 
ATOM   3787 C  CG   . PHE A 1 245 ? -27.77531 -15.68990 -15.26078 1.000 10.38811 ? 1704 PHE A CG   1 
ATOM   3788 C  CD1  . PHE A 1 245 ? -29.07129 -15.33211 -14.91798 1.000 11.62246 ? 1704 PHE A CD1  1 
ATOM   3789 C  CD2  . PHE A 1 245 ? -26.99140 -14.74919 -15.89473 1.000 10.59866 ? 1704 PHE A CD2  1 
ATOM   3790 C  CE1  . PHE A 1 245 ? -29.54803 -14.05398 -15.18034 1.000 11.64089 ? 1704 PHE A CE1  1 
ATOM   3791 C  CE2  . PHE A 1 245 ? -27.47571 -13.47212 -16.15135 1.000 12.05410 ? 1704 PHE A CE2  1 
ATOM   3792 C  CZ   . PHE A 1 245 ? -28.75713 -13.13294 -15.78607 1.000 12.09621 ? 1704 PHE A CZ   1 
ATOM   3793 H  H    . PHE A 1 245 ? -26.79812 -17.06893 -12.46765 1.000 12.52853 ? 1704 PHE A H    1 
ATOM   3794 H  HA   . PHE A 1 245 ? -28.78975 -17.98111 -13.99174 1.000 12.24745 ? 1704 PHE A HA   1 
ATOM   3795 H  HB2  . PHE A 1 245 ? -26.28048 -17.01337 -14.92676 1.000 13.08755 ? 1704 PHE A HB2  1 
ATOM   3796 H  HB3  . PHE A 1 245 ? -27.41796 -17.58423 -15.87843 1.000 13.08755 ? 1704 PHE A HB3  1 
ATOM   3797 H  HD1  . PHE A 1 245 ? -29.62703 -15.95495 -14.50796 1.000 13.94975 ? 1704 PHE A HD1  1 
ATOM   3798 H  HD2  . PHE A 1 245 ? -26.12667 -14.97242 -16.15416 1.000 12.72119 ? 1704 PHE A HD2  1 
ATOM   3799 H  HE1  . PHE A 1 245 ? -30.41708 -13.82763 -14.93862 1.000 13.97186 ? 1704 PHE A HE1  1 
ATOM   3800 H  HE2  . PHE A 1 245 ? -26.93176 -12.84540 -16.57115 1.000 14.46771 ? 1704 PHE A HE2  1 
ATOM   3801 H  HZ   . PHE A 1 245 ? -29.07993 -12.27694 -15.95328 1.000 14.51824 ? 1704 PHE A HZ   1 
ATOM   3802 N  N    . PRO A 1 246 ? -27.66640 -20.26473 -14.49125 1.000 10.33810 ? 1705 PRO A N    1 
ATOM   3803 C  CA   . PRO A 1 246 ? -26.84835 -21.43576 -14.85624 1.000 10.91975 ? 1705 PRO A CA   1 
ATOM   3804 C  C    . PRO A 1 246 ? -25.92709 -21.04008 -16.00284 1.000 11.09345 ? 1705 PRO A C    1 
ATOM   3805 O  O    . PRO A 1 246 ? -26.25217 -20.15267 -16.79549 1.000 11.30664 ? 1705 PRO A O    1 
ATOM   3806 C  CB   . PRO A 1 246 ? -27.89248 -22.46187 -15.32088 1.000 11.80933 ? 1705 PRO A CB   1 
ATOM   3807 C  CG   . PRO A 1 246 ? -28.97860 -21.64179 -15.87196 1.000 12.48572 ? 1705 PRO A CG   1 
ATOM   3808 C  CD   . PRO A 1 246 ? -29.03914 -20.35589 -15.02806 1.000 11.43034 ? 1705 PRO A CD   1 
ATOM   3809 H  HA   . PRO A 1 246 ? -26.35301 -21.80165 -14.10681 1.000 13.10650 ? 1705 PRO A HA   1 
ATOM   3810 H  HB2  . PRO A 1 246 ? -27.51209 -23.04147 -15.99932 1.000 14.17399 ? 1705 PRO A HB2  1 
ATOM   3811 H  HB3  . PRO A 1 246 ? -28.19973 -22.99008 -14.56756 1.000 14.17399 ? 1705 PRO A HB3  1 
ATOM   3812 H  HG2  . PRO A 1 246 ? -28.78592 -21.43115 -16.79900 1.000 14.98567 ? 1705 PRO A HG2  1 
ATOM   3813 H  HG3  . PRO A 1 246 ? -29.81499 -22.12905 -15.80937 1.000 14.98567 ? 1705 PRO A HG3  1 
ATOM   3814 H  HD2  . PRO A 1 246 ? -29.24966 -19.58633 -15.57974 1.000 13.71920 ? 1705 PRO A HD2  1 
ATOM   3815 H  HD3  . PRO A 1 246 ? -29.68865 -20.43871 -14.31240 1.000 13.71920 ? 1705 PRO A HD3  1 
ATOM   3816 N  N    . GLY A 1 247 ? -24.76033 -21.68309 -16.08169 1.000 10.64603 ? 1706 GLY A N    1 
ATOM   3817 C  CA   . GLY A 1 247 ? -23.77760 -21.24317 -17.06109 1.000 10.39600 ? 1706 GLY A CA   1 
ATOM   3818 C  C    . GLY A 1 247 ? -22.73347 -22.25146 -17.51604 1.000 10.59603 ? 1706 GLY A C    1 
ATOM   3819 O  O    . GLY A 1 247 ? -22.00445 -21.97386 -18.46017 1.000 11.29874 ? 1706 GLY A O    1 
ATOM   3820 H  H    . GLY A 1 247 ? -24.52621 -22.35235 -15.59499 1.000 12.77804 ? 1706 GLY A H    1 
ATOM   3821 H  HA2  . GLY A 1 247 ? -24.25408 -20.95192 -17.85421 1.000 12.47800 ? 1706 GLY A HA2  1 
ATOM   3822 H  HA3  . GLY A 1 247 ? -23.29747 -20.48834 -16.68611 1.000 12.47800 ? 1706 GLY A HA3  1 
ATOM   3823 N  N    . LEU A 1 248 ? -22.63302 -23.41077 -16.85976 1.000 9.98016  ? 1707 LEU A N    1 
ATOM   3824 C  CA   . LEU A 1 248 ? -21.60656 -24.37468 -17.24355 1.000 9.88278  ? 1707 LEU A CA   1 
ATOM   3825 C  C    . LEU A 1 248 ? -21.74552 -24.81276 -18.69424 1.000 10.35916 ? 1707 LEU A C    1 
ATOM   3826 O  O    . LEU A 1 248 ? -20.74024 -24.94648 -19.40480 1.000 10.86448 ? 1707 LEU A O    1 
ATOM   3827 C  CB   . LEU A 1 248 ? -21.61970 -25.57270 -16.30670 1.000 10.48812 ? 1707 LEU A CB   1 
ATOM   3828 C  CG   . LEU A 1 248 ? -20.88490 -25.34310 -14.99066 1.000 10.62235 ? 1707 LEU A CG   1 
ATOM   3829 C  CD1  . LEU A 1 248 ? -21.29144 -26.34378 -13.94976 1.000 10.34863 ? 1707 LEU A CD1  1 
ATOM   3830 C  CD2  . LEU A 1 248 ? -19.34687 -25.33221 -15.18219 1.000 11.61457 ? 1707 LEU A CD2  1 
ATOM   3831 H  H    . LEU A 1 248 ? -23.13497 -23.65531 -16.20567 1.000 11.97899 ? 1707 LEU A H    1 
ATOM   3832 H  HA   . LEU A 1 248 ? -20.74248 -23.94286 -17.15523 1.000 11.86214 ? 1707 LEU A HA   1 
ATOM   3833 H  HB2  . LEU A 1 248 ? -22.54104 -25.79108 -16.09614 1.000 12.58854 ? 1707 LEU A HB2  1 
ATOM   3834 H  HB3  . LEU A 1 248 ? -21.19549 -26.32104 -16.75495 1.000 12.58854 ? 1707 LEU A HB3  1 
ATOM   3835 H  HG   . LEU A 1 248 ? -21.13827 -24.46534 -14.66470 1.000 12.74961 ? 1707 LEU A HG   1 
ATOM   3836 H  HD11 . LEU A 1 248 ? -20.80642 -26.16128 -13.12979 1.000 12.42115 ? 1707 LEU A HD11 1 
ATOM   3837 H  HD12 . LEU A 1 248 ? -22.24572 -26.26712 -13.79367 1.000 12.42115 ? 1707 LEU A HD12 1 
ATOM   3838 H  HD13 . LEU A 1 248 ? -21.07893 -27.23496 -14.26842 1.000 12.42115 ? 1707 LEU A HD13 1 
ATOM   3839 H  HD21 . LEU A 1 248 ? -18.92158 -25.22748 -14.31670 1.000 13.94028 ? 1707 LEU A HD21 1 
ATOM   3840 H  HD22 . LEU A 1 248 ? -19.07298 -26.17053 -15.58605 1.000 13.94028 ? 1707 LEU A HD22 1 
ATOM   3841 H  HD23 . LEU A 1 248 ? -19.10592 -24.59197 -15.76088 1.000 13.94028 ? 1707 LEU A HD23 1 
ATOM   3842 N  N    . GLU A 1 249 ? -22.96774 -25.08787 -19.14763 1.000 10.72499 ? 1708 GLU A N    1 
ATOM   3843 C  CA   . GLU A 1 249 ? -23.15296 -25.64428 -20.48185 1.000 11.06714 ? 1708 GLU A CA   1 
ATOM   3844 C  C    . GLU A 1 249 ? -23.01585 -24.61697 -21.59412 1.000 11.63036 ? 1708 GLU A C    1 
ATOM   3845 O  O    . GLU A 1 249 ? -22.79817 -25.00783 -22.74937 1.000 12.95157 ? 1708 GLU A O    1 
ATOM   3846 C  CB   . GLU A 1 249 ? -24.49095 -26.38051 -20.55123 1.000 11.73564 ? 1708 GLU A CB   1 
ATOM   3847 C  CG   . GLU A 1 249 ? -24.47259 -27.66384 -19.73524 1.000 12.12779 ? 1708 GLU A CG   1 
ATOM   3848 C  CD   . GLU A 1 249 ? -25.86272 -28.18797 -19.47485 1.000 12.35150 ? 1708 GLU A CD   1 
ATOM   3849 O  OE1  . GLU A 1 249 ? -26.48231 -27.76514 -18.46848 1.000 12.59100 ? 1708 GLU A OE1  1 
ATOM   3850 O  OE2  . GLU A 1 249 ? -26.30066 -29.08374 -20.24872 1.000 13.44373 ? 1708 GLU A OE2  1 
ATOM   3851 H  H    . GLU A 1 249 ? -23.69528 -24.96246 -18.70654 1.000 12.87278 ? 1708 GLU A H    1 
ATOM   3852 H  HA   . GLU A 1 249 ? -22.45954 -26.30120 -20.65073 1.000 13.28336 ? 1708 GLU A HA   1 
ATOM   3853 H  HB2  . GLU A 1 249 ? -25.18978 -25.80661 -20.20028 1.000 14.08556 ? 1708 GLU A HB2  1 
ATOM   3854 H  HB3  . GLU A 1 249 ? -24.68198 -26.60940 -21.47428 1.000 14.08556 ? 1708 GLU A HB3  1 
ATOM   3855 H  HG2  . GLU A 1 249 ? -23.97843 -28.34317 -20.22023 1.000 14.55614 ? 1708 GLU A HG2  1 
ATOM   3856 H  HG3  . GLU A 1 249 ? -24.04830 -27.49203 -18.88004 1.000 14.55614 ? 1708 GLU A HG3  1 
ATOM   3857 N  N    . THR A 1 250 ? -23.12324 -23.32265 -21.27945 1.000 10.92765 ? 1709 THR A N    1 
ATOM   3858 C  CA   . THR A 1 250 ? -23.05505 -22.27695 -22.28415 1.000 10.97239 ? 1709 THR A CA   1 
ATOM   3859 C  C    . THR A 1 250 ? -21.73615 -21.51789 -22.31814 1.000 10.29336 ? 1709 THR A C    1 
ATOM   3860 O  O    . THR A 1 250 ? -21.46324 -20.86942 -23.32818 1.000 11.04871 ? 1709 THR A O    1 
ATOM   3861 C  CB   . THR A 1 250 ? -24.21887 -21.28556 -22.11055 1.000 11.12504 ? 1709 THR A CB   1 
ATOM   3862 O  OG1  . THR A 1 250 ? -24.31314 -20.87286 -20.74823 1.000 11.20136 ? 1709 THR A OG1  1 
ATOM   3863 C  CG2  . THR A 1 250 ? -25.53183 -21.95758 -22.51262 1.000 11.94619 ? 1709 THR A CG2  1 
ATOM   3864 H  H    . THR A 1 250 ? -23.23732 -23.02839 -20.47945 1.000 13.11597 ? 1709 THR A H    1 
ATOM   3865 H  HA   . THR A 1 250 ? -23.15352 -22.69463 -23.15407 1.000 13.16966 ? 1709 THR A HA   1 
ATOM   3866 H  HB   . THR A 1 250 ? -24.06762 -20.50767 -22.66993 1.000 13.35284 ? 1709 THR A HB   1 
ATOM   3867 H  HG1  . THR A 1 250 ? -23.60144 -20.49372 -20.51299 1.000 13.44443 ? 1709 THR A HG1  1 
ATOM   3868 H  HG21 . THR A 1 250 ? -26.26873 -21.33567 -22.40722 1.000 14.33822 ? 1709 THR A HG21 1 
ATOM   3869 H  HG22 . THR A 1 250 ? -25.48925 -22.24106 -23.43930 1.000 14.33822 ? 1709 THR A HG22 1 
ATOM   3870 H  HG23 . THR A 1 250 ? -25.69230 -22.73353 -21.95311 1.000 14.33822 ? 1709 THR A HG23 1 
ATOM   3871 N  N    . MET A 1 251 ? -20.91159 -21.60093 -21.26943 1.000 10.70130 ? 1710 MET A N    1 
ATOM   3872 C  CA   . MET A 1 251 ? -19.71404 -20.76044 -21.19329 1.000 10.48022 ? 1710 MET A CA   1 
ATOM   3873 C  C    . MET A 1 251 ? -18.78536 -20.97017 -22.37448 1.000 10.30389 ? 1710 MET A C    1 
ATOM   3874 O  O    . MET A 1 251 ? -18.42302 -20.01871 -23.07874 1.000 10.89080 ? 1710 MET A O    1 
ATOM   3875 C  CB   . MET A 1 251 ? -18.97346 -20.98471 -19.87525 1.000 10.96186 ? 1710 MET A CB   1 
ATOM   3876 C  CG   . MET A 1 251 ? -17.73568 -20.10500 -19.77214 1.000 11.11714 ? 1710 MET A CG   1 
ATOM   3877 S  SD   . MET A 1 251 ? -17.05105 -19.94068 -18.13213 1.000 11.06187 ? 1710 MET A SD   1 
ATOM   3878 C  CE   . MET A 1 251 ? -16.73135 -21.65371 -17.66572 1.000 11.87249 ? 1710 MET A CE   1 
ATOM   3879 H  H    . MET A 1 251 ? -21.02128 -22.12800 -20.59879 1.000 12.84436 ? 1710 MET A H    1 
ATOM   3880 H  HA   . MET A 1 251 ? -20.01627 -19.83883 -21.20689 1.000 12.57907 ? 1710 MET A HA   1 
ATOM   3881 H  HB2  . MET A 1 251 ? -19.56338 -20.76970 -19.13588 1.000 13.15703 ? 1710 MET A HB2  1 
ATOM   3882 H  HB3  . MET A 1 251 ? -18.69465 -21.91203 -19.81837 1.000 13.15703 ? 1710 MET A HB3  1 
ATOM   3883 H  HG2  . MET A 1 251 ? -17.04385 -20.48233 -20.33773 1.000 13.34337 ? 1710 MET A HG2  1 
ATOM   3884 H  HG3  . MET A 1 251 ? -17.96647 -19.21443 -20.07961 1.000 13.34337 ? 1710 MET A HG3  1 
ATOM   3885 H  HE1  . MET A 1 251 ? -16.31332 -21.66998 -16.79057 1.000 14.24979 ? 1710 MET A HE1  1 
ATOM   3886 H  HE2  . MET A 1 251 ? -17.57247 -22.13613 -17.63954 1.000 14.24979 ? 1710 MET A HE2  1 
ATOM   3887 H  HE3  . MET A 1 251 ? -16.14034 -22.05469 -18.32210 1.000 14.24979 ? 1710 MET A HE3  1 
ATOM   3888 N  N    . LEU A 1 252 ? -18.36187 -22.20599 -22.58576 1.000 10.16440 ? 1711 LEU A N    1 
ATOM   3889 C  CA   . LEU A 1 252 ? -17.36981 -22.45259 -23.63132 1.000 10.61708 ? 1711 LEU A CA   1 
ATOM   3890 C  C    . LEU A 1 252 ? -17.94374 -22.17114 -25.02149 1.000 11.86723 ? 1711 LEU A C    1 
ATOM   3891 O  O    . LEU A 1 252 ? -17.29002 -21.50382 -25.82213 1.000 12.21727 ? 1711 LEU A O    1 
ATOM   3892 C  CB   . LEU A 1 252 ? -16.74990 -23.84433 -23.49486 1.000 10.63551 ? 1711 LEU A CB   1 
ATOM   3893 C  CG   . LEU A 1 252 ? -15.68565 -24.15918 -24.53490 1.000 11.23821 ? 1711 LEU A CG   1 
ATOM   3894 C  CD1  . LEU A 1 252 ? -14.51447 -23.18286 -24.41206 1.000 11.74090 ? 1711 LEU A CD1  1 
ATOM   3895 C  CD2  . LEU A 1 252 ? -15.24056 -25.62022 -24.38666 1.000 11.61194 ? 1711 LEU A CD2  1 
ATOM   3896 H  H    . LEU A 1 252 ? -18.62316 -22.90130 -22.15231 1.000 12.20007 ? 1711 LEU A H    1 
ATOM   3897 H  HA   . LEU A 1 252 ? -16.63746 -21.82520 -23.52670 1.000 12.74330 ? 1711 LEU A HA   1 
ATOM   3898 H  HB2  . LEU A 1 252 ? -16.33679 -23.91438 -22.62003 1.000 12.76541 ? 1711 LEU A HB2  1 
ATOM   3899 H  HB3  . LEU A 1 252 ? -17.45343 -24.50622 -23.58349 1.000 12.76541 ? 1711 LEU A HB3  1 
ATOM   3900 H  HG   . LEU A 1 252 ? -16.04526 -24.05118 -25.42929 1.000 13.48865 ? 1711 LEU A HG   1 
ATOM   3901 H  HD11 . LEU A 1 252 ? -13.78814 -23.48817 -24.97786 1.000 14.09188 ? 1711 LEU A HD11 1 
ATOM   3902 H  HD12 . LEU A 1 252 ? -14.80645 -22.30219 -24.69504 1.000 14.09188 ? 1711 LEU A HD12 1 
ATOM   3903 H  HD13 . LEU A 1 252 ? -14.22345 -23.15353 -23.48721 1.000 14.09188 ? 1711 LEU A HD13 1 
ATOM   3904 H  HD21 . LEU A 1 252 ? -14.55712 -25.81080 -25.04809 1.000 13.93712 ? 1711 LEU A HD21 1 
ATOM   3905 H  HD22 . LEU A 1 252 ? -14.88355 -25.75262 -23.49452 1.000 13.93712 ? 1711 LEU A HD22 1 
ATOM   3906 H  HD23 . LEU A 1 252 ? -16.00621 -26.19927 -24.52586 1.000 13.93712 ? 1711 LEU A HD23 1 
ATOM   3907 N  N    . PRO A 1 253 ? -19.16872 -22.59832 -25.35486 1.000 12.12516 ? 1712 PRO A N    1 
ATOM   3908 C  CA   . PRO A 1 253 ? -19.68818 -22.22365 -26.68459 1.000 12.50941 ? 1712 PRO A CA   1 
ATOM   3909 C  C    . PRO A 1 253 ? -19.73914 -20.71763 -26.92943 1.000 11.20400 ? 1712 PRO A C    1 
ATOM   3910 O  O    . PRO A 1 253 ? -19.42435 -20.25163 -28.03169 1.000 12.00935 ? 1712 PRO A O    1 
ATOM   3911 C  CB   . PRO A 1 253 ? -21.08669 -22.85443 -26.72400 1.000 14.12013 ? 1712 PRO A CB   1 
ATOM   3912 C  CG   . PRO A 1 253 ? -20.99883 -24.00371 -25.78455 1.000 14.10171 ? 1712 PRO A CG   1 
ATOM   3913 C  CD   . PRO A 1 253 ? -20.00860 -23.62623 -24.69697 1.000 12.34361 ? 1712 PRO A CD   1 
ATOM   3914 H  HA   . PRO A 1 253 ? -19.13323 -22.63764 -27.36395 1.000 15.01409 ? 1712 PRO A HA   1 
ATOM   3915 H  HB2  . PRO A 1 253 ? -21.75025 -22.21149 -26.42867 1.000 16.94696 ? 1712 PRO A HB2  1 
ATOM   3916 H  HB3  . PRO A 1 253 ? -21.29176 -23.15332 -27.62373 1.000 16.94696 ? 1712 PRO A HB3  1 
ATOM   3917 H  HG2  . PRO A 1 253 ? -21.87375 -24.17233 -25.40116 1.000 16.92485 ? 1712 PRO A HG2  1 
ATOM   3918 H  HG3  . PRO A 1 253 ? -20.69038 -24.78793 -26.26493 1.000 16.92485 ? 1712 PRO A HG3  1 
ATOM   3919 H  HD2  . PRO A 1 253 ? -20.46572 -23.25794 -23.92476 1.000 14.81513 ? 1712 PRO A HD2  1 
ATOM   3920 H  HD3  . PRO A 1 253 ? -19.47539 -24.39223 -24.43273 1.000 14.81513 ? 1712 PRO A HD3  1 
ATOM   3921 N  N    . LEU A 1 254 ? -20.13464 -19.93298 -25.93008 1.000 11.48298 ? 1713 LEU A N    1 
ATOM   3922 C  CA   . LEU A 1 254 ? -20.13750 -18.48747 -26.09226 1.000 11.68037 ? 1713 LEU A CA   1 
ATOM   3923 C  C    . LEU A 1 254 ? -18.73219 -17.96096 -26.37761 1.000 11.03556 ? 1713 LEU A C    1 
ATOM   3924 O  O    . LEU A 1 254 ? -18.53844 -17.13507 -27.27524 1.000 11.94092 ? 1713 LEU A O    1 
ATOM   3925 C  CB   . LEU A 1 254 ? -20.70687 -17.83250 -24.83850 1.000 11.39086 ? 1713 LEU A CB   1 
ATOM   3926 C  CG   . LEU A 1 254 ? -22.21216 -17.99341 -24.56569 1.000 12.05146 ? 1713 LEU A CG   1 
ATOM   3927 C  CD1  . LEU A 1 254 ? -22.50942 -17.65963 -23.11456 1.000 11.76722 ? 1713 LEU A CD1  1 
ATOM   3928 C  CD2  . LEU A 1 254 ? -22.98734 -17.10388 -25.51935 1.000 12.63838 ? 1713 LEU A CD2  1 
ATOM   3929 H  H    . LEU A 1 254 ? -20.40150 -20.20996 -25.16089 1.000 13.78237 ? 1713 LEU A H    1 
ATOM   3930 H  HA   . LEU A 1 254 ? -20.70343 -18.25688 -26.84555 1.000 14.01924 ? 1713 LEU A HA   1 
ATOM   3931 H  HB2  . LEU A 1 254 ? -20.24267 -18.20636 -24.07323 1.000 13.67183 ? 1713 LEU A HB2  1 
ATOM   3932 H  HB3  . LEU A 1 254 ? -20.53403 -16.87991 -24.89849 1.000 13.67183 ? 1713 LEU A HB3  1 
ATOM   3933 H  HG   . LEU A 1 254 ? -22.49521 -18.90922 -24.71426 1.000 14.46455 ? 1713 LEU A HG   1 
ATOM   3934 H  HD11 . LEU A 1 254 ? -23.46124 -17.75903 -22.95623 1.000 14.12346 ? 1713 LEU A HD11 1 
ATOM   3935 H  HD12 . LEU A 1 254 ? -22.01384 -18.26673 -22.54296 1.000 14.12346 ? 1713 LEU A HD12 1 
ATOM   3936 H  HD13 . LEU A 1 254 ? -22.23866 -16.74487 -22.93906 1.000 14.12346 ? 1713 LEU A HD13 1 
ATOM   3937 H  HD21 . LEU A 1 254 ? -23.93413 -17.17906 -25.32227 1.000 15.16885 ? 1713 LEU A HD21 1 
ATOM   3938 H  HD22 . LEU A 1 254 ? -22.69683 -16.18592 -25.40165 1.000 15.16885 ? 1713 LEU A HD22 1 
ATOM   3939 H  HD23 . LEU A 1 254 ? -22.81514 -17.39118 -26.42968 1.000 15.16885 ? 1713 LEU A HD23 1 
ATOM   3940 N  N    . LEU A 1 255 ? -17.74287 -18.43633 -25.61724 1.000 11.01976 ? 1714 LEU A N    1 
ATOM   3941 C  CA   . LEU A 1 255 ? -16.37512 -17.96080 -25.77952 1.000 10.80658 ? 1714 LEU A CA   1 
ATOM   3942 C  C    . LEU A 1 255 ? -15.75257 -18.45054 -27.08225 1.000 11.30927 ? 1714 LEU A C    1 
ATOM   3943 O  O    . LEU A 1 255 ? -14.99167 -17.71273 -27.71445 1.000 11.85144 ? 1714 LEU A O    1 
ATOM   3944 C  CB   . LEU A 1 255 ? -15.55426 -18.38536 -24.57327 1.000 11.12241 ? 1714 LEU A CB   1 
ATOM   3945 C  CG   . LEU A 1 255 ? -15.93322 -17.64241 -23.29738 1.000 11.47508 ? 1714 LEU A CG   1 
ATOM   3946 C  CD1  . LEU A 1 255 ? -15.34949 -18.34757 -22.08282 1.000 11.94619 ? 1714 LEU A CD1  1 
ATOM   3947 C  CD2  . LEU A 1 255 ? -15.46031 -16.18866 -23.33855 1.000 12.36203 ? 1714 LEU A CD2  1 
ATOM   3948 H  H    . LEU A 1 255 ? -17.83935 -19.03156 -25.00405 1.000 13.22651 ? 1714 LEU A H    1 
ATOM   3949 H  HA   . LEU A 1 255 ? -16.37490 -16.99169 -25.82097 1.000 12.97069 ? 1714 LEU A HA   1 
ATOM   3950 H  HB2  . LEU A 1 255 ? -15.69085 -19.33326 -24.41925 1.000 13.34968 ? 1714 LEU A HB2  1 
ATOM   3951 H  HB3  . LEU A 1 255 ? -14.61754 -18.21027 -24.75438 1.000 13.34968 ? 1714 LEU A HB3  1 
ATOM   3952 H  HG   . LEU A 1 255 ? -16.90024 -17.63687 -23.22170 1.000 13.77289 ? 1714 LEU A HG   1 
ATOM   3953 H  HD11 . LEU A 1 255 ? -15.60324 -17.86104 -21.28294 1.000 14.33822 ? 1714 LEU A HD11 1 
ATOM   3954 H  HD12 . LEU A 1 255 ? -15.69846 -19.25182 -22.04464 1.000 14.33822 ? 1714 LEU A HD12 1 
ATOM   3955 H  HD13 . LEU A 1 255 ? -14.38316 -18.36911 -22.16430 1.000 14.33822 ? 1714 LEU A HD13 1 
ATOM   3956 H  HD21 . LEU A 1 255 ? -15.61916 -15.78027 -22.47317 1.000 14.83723 ? 1714 LEU A HD21 1 
ATOM   3957 H  HD22 . LEU A 1 255 ? -14.51246 -16.17060 -23.54386 1.000 14.83723 ? 1714 LEU A HD22 1 
ATOM   3958 H  HD23 . LEU A 1 255 ? -15.95635 -15.71450 -24.02414 1.000 14.83723 ? 1714 LEU A HD23 1 
ATOM   3959 N  N    . LEU A 1 256 ? -16.07697 -19.67508 -27.52441 1.000 12.01462 ? 1715 LEU A N    1 
ATOM   3960 C  CA   . LEU A 1 256 ? -15.58165 -20.14690 -28.81737 1.000 12.90420 ? 1715 LEU A CA   1 
ATOM   3961 C  C    . LEU A 1 256 ? -16.15031 -19.31377 -29.95405 1.000 13.06211 ? 1715 LEU A C    1 
ATOM   3962 O  O    . LEU A 1 256 ? -15.46637 -19.05843 -30.95304 1.000 13.35952 ? 1715 LEU A O    1 
ATOM   3963 C  CB   . LEU A 1 256 ? -15.95357 -21.61456 -29.04779 1.000 13.15423 ? 1715 LEU A CB   1 
ATOM   3964 C  CG   . LEU A 1 256 ? -15.22227 -22.62073 -28.15337 1.000 13.98064 ? 1715 LEU A CG   1 
ATOM   3965 C  CD1  . LEU A 1 256 ? -15.79121 -24.02705 -28.40223 1.000 15.27553 ? 1715 LEU A CD1  1 
ATOM   3966 C  CD2  . LEU A 1 256 ? -13.71918 -22.57768 -28.38987 1.000 14.54650 ? 1715 LEU A CD2  1 
ATOM   3967 H  H    . LEU A 1 256 ? -16.57169 -20.23740 -27.10175 1.000 14.42034 ? 1715 LEU A H    1 
ATOM   3968 H  HA   . LEU A 1 256 ? -14.61416 -20.07743 -28.81043 1.000 15.48784 ? 1715 LEU A HA   1 
ATOM   3969 H  HB2  . LEU A 1 256 ? -16.90417 -21.71810 -28.88492 1.000 15.78787 ? 1715 LEU A HB2  1 
ATOM   3970 H  HB3  . LEU A 1 256 ? -15.74811 -21.84096 -29.96835 1.000 15.78787 ? 1715 LEU A HB3  1 
ATOM   3971 H  HG   . LEU A 1 256 ? -15.36119 -22.39147 -27.22115 1.000 16.77957 ? 1715 LEU A HG   1 
ATOM   3972 H  HD11 . LEU A 1 256 ? -15.32455 -24.66129 -27.83579 1.000 18.33344 ? 1715 LEU A HD11 1 
ATOM   3973 H  HD12 . LEU A 1 256 ? -16.73752 -24.02713 -28.18915 1.000 18.33344 ? 1715 LEU A HD12 1 
ATOM   3974 H  HD13 . LEU A 1 256 ? -15.66218 -24.25938 -29.33511 1.000 18.33344 ? 1715 LEU A HD13 1 
ATOM   3975 H  HD21 . LEU A 1 256 ? -13.30748 -23.33414 -27.94359 1.000 17.45860 ? 1715 LEU A HD21 1 
ATOM   3976 H  HD22 . LEU A 1 256 ? -13.54812 -22.62308 -29.34359 1.000 17.45860 ? 1715 LEU A HD22 1 
ATOM   3977 H  HD23 . LEU A 1 256 ? -13.36642 -21.74901 -28.02962 1.000 17.45860 ? 1715 LEU A HD23 1 
ATOM   3978 N  N    . THR A 1 257 ? -17.39801 -18.85393 -29.80546 1.000 13.86484 ? 1716 THR A N    1 
ATOM   3979 C  CA   . THR A 1 257 ? -17.98087 -17.96845 -30.80724 1.000 13.74640 ? 1716 THR A CA   1 
ATOM   3980 C  C    . THR A 1 257 ? -17.15480 -16.69614 -30.92050 1.000 13.39373 ? 1716 THR A C    1 
ATOM   3981 O  O    . THR A 1 257 ? -16.84636 -16.21483 -32.02195 1.000 14.28331 ? 1716 THR A O    1 
ATOM   3982 C  CB   . THR A 1 257 ? -19.42116 -17.62133 -30.42043 1.000 13.85168 ? 1716 THR A CB   1 
ATOM   3983 O  OG1  . THR A 1 257 ? -20.18427 -18.81579 -30.23293 1.000 14.06750 ? 1716 THR A OG1  1 
ATOM   3984 C  CG2  . THR A 1 257 ? -20.07644 -16.82408 -31.53450 1.000 14.71231 ? 1716 THR A CG2  1 
ATOM   3985 H  H    . THR A 1 257 ? -17.91590 -19.03850 -29.14415 1.000 16.64060 ? 1716 THR A H    1 
ATOM   3986 H  HA   . THR A 1 257 ? -17.99501 -18.41952 -31.66586 1.000 16.49848 ? 1716 THR A HA   1 
ATOM   3987 H  HB   . THR A 1 257 ? -19.41143 -17.10381 -29.60008 1.000 16.62482 ? 1716 THR A HB   1 
ATOM   3988 H  HG1  . THR A 1 257 ? -19.84789 -19.27798 -29.61744 1.000 16.88379 ? 1716 THR A HG1  1 
ATOM   3989 H  HG21 . THR A 1 257 ? -21.02828 -16.74084 -31.36729 1.000 17.65757 ? 1716 THR A HG21 1 
ATOM   3990 H  HG22 . THR A 1 257 ? -19.68633 -15.93723 -31.58153 1.000 17.65757 ? 1716 THR A HG22 1 
ATOM   3991 H  HG23 . THR A 1 257 ? -19.94416 -17.27168 -32.38483 1.000 17.65757 ? 1716 THR A HG23 1 
ATOM   3992 N  N    . ALA A 1 258 ? -16.80244 -16.13367 -29.77267 1.000 12.73839 ? 1717 ALA A N    1 
ATOM   3993 C  CA   . ALA A 1 258 ? -15.97460 -14.92940 -29.74059 1.000 12.74892 ? 1717 ALA A CA   1 
ATOM   3994 C  C    . ALA A 1 258 ? -14.59635 -15.17740 -30.34577 1.000 13.13844 ? 1717 ALA A C    1 
ATOM   3995 O  O    . ALA A 1 258 ? -14.06121 -14.31249 -31.04773 1.000 14.64125 ? 1717 ALA A O    1 
ATOM   3996 C  CB   . ALA A 1 258 ? -15.87252 -14.43191 -28.29900 1.000 13.22003 ? 1717 ALA A CB   1 
ATOM   3997 H  H    . ALA A 1 258 ? -17.02732 -16.42624 -28.99587 1.000 15.28886 ? 1717 ALA A H    1 
ATOM   3998 H  HA   . ALA A 1 258 ? -16.39244 -14.23436 -30.27278 1.000 15.30150 ? 1717 ALA A HA   1 
ATOM   3999 H  HB1  . ALA A 1 258 ? -15.33751 -13.62299 -28.28122 1.000 15.86683 ? 1717 ALA A HB1  1 
ATOM   4000 H  HB2  . ALA A 1 258 ? -16.76412 -14.24620 -27.96513 1.000 15.86683 ? 1717 ALA A HB2  1 
ATOM   4001 H  HB3  . ALA A 1 258 ? -15.45266 -15.11816 -27.75708 1.000 15.86683 ? 1717 ALA A HB3  1 
ATOM   4002 N  N    . VAL A 1 259 ? -13.99650 -16.34478 -30.08675 1.000 12.49626 ? 1718 VAL A N    1 
ATOM   4003 C  CA   . VAL A 1 259 ? -12.71672 -16.66073 -30.71966 1.000 14.01749 ? 1718 VAL A CA   1 
ATOM   4004 C  C    . VAL A 1 259 ? -12.87784 -16.68839 -32.23602 1.000 16.00194 ? 1718 VAL A C    1 
ATOM   4005 O  O    . VAL A 1 259 ? -12.04094 -16.15451 -32.98468 1.000 16.92573 ? 1718 VAL A O    1 
ATOM   4006 C  CB   . VAL A 1 259 ? -12.16406 -17.99334 -30.19193 1.000 14.14645 ? 1718 VAL A CB   1 
ATOM   4007 C  CG1  . VAL A 1 259 ? -10.96605 -18.44944 -31.01821 1.000 15.06498 ? 1718 VAL A CG1  1 
ATOM   4008 C  CG2  . VAL A 1 259 ? -11.74930 -17.87939 -28.73976 1.000 14.18330 ? 1718 VAL A CG2  1 
ATOM   4009 H  H    . VAL A 1 259 ? -14.30292 -16.95346 -29.56215 1.000 14.99831 ? 1718 VAL A H    1 
ATOM   4010 H  HA   . VAL A 1 259 ? -12.08056 -15.96486 -30.49170 1.000 16.82379 ? 1718 VAL A HA   1 
ATOM   4011 H  HB   . VAL A 1 259 ? -12.87176 -18.65277 -30.26416 1.000 16.97854 ? 1718 VAL A HB   1 
ATOM   4012 H  HG11 . VAL A 1 259 ? -10.47431 -19.11959 -30.51822 1.000 18.08078 ? 1718 VAL A HG11 1 
ATOM   4013 H  HG12 . VAL A 1 259 ? -11.28375 -18.82688 -31.85338 1.000 18.08078 ? 1718 VAL A HG12 1 
ATOM   4014 H  HG13 . VAL A 1 259 ? -10.39590 -17.68517 -31.19631 1.000 18.08078 ? 1718 VAL A HG13 1 
ATOM   4015 H  HG21 . VAL A 1 259 ? -11.43392 -18.74375 -28.43265 1.000 17.02276 ? 1718 VAL A HG21 1 
ATOM   4016 H  HG22 . VAL A 1 259 ? -11.03951 -17.22253 -28.66467 1.000 17.02276 ? 1718 VAL A HG22 1 
ATOM   4017 H  HG23 . VAL A 1 259 ? -12.51500 -17.60061 -28.21357 1.000 17.02276 ? 1718 VAL A HG23 1 
ATOM   4018 N  N    . SER A 1 260 ? -13.94979 -17.34292 -32.71131 1.000 17.80479 ? 1719 SER A N    1 
ATOM   4019 C  CA   A SER A 1 260 ? -14.17634 -17.46683 -34.14759 0.243 18.65752 ? 1719 SER A CA   1 
ATOM   4020 C  CA   B SER A 1 260 ? -14.19442 -17.46650 -34.14604 0.757 18.85754 ? 1719 SER A CA   1 
ATOM   4021 C  C    . SER A 1 260 ? -14.36700 -16.11015 -34.80663 1.000 19.42867 ? 1719 SER A C    1 
ATOM   4022 O  O    . SER A 1 260 ? -14.05913 -15.95495 -35.99418 1.000 21.48680 ? 1719 SER A O    1 
ATOM   4023 C  CB   A SER A 1 260 ? -15.39933 -18.35195 -34.40245 0.243 19.00756 ? 1719 SER A CB   1 
ATOM   4024 C  CB   B SER A 1 260 ? -15.45104 -18.31580 -34.40435 0.757 19.76292 ? 1719 SER A CB   1 
ATOM   4025 O  OG   A SER A 1 260 ? -15.48623 -18.75118 -35.75938 0.243 19.18390 ? 1719 SER A OG   1 
ATOM   4026 O  OG   B SER A 1 260 ? -16.66663 -17.54919 -34.34583 0.757 20.70250 ? 1719 SER A OG   1 
ATOM   4027 H  H    A SER A 1 260 ? -14.55098 -17.71815 -32.22411 0.243 21.36854 ? 1719 SER A H    1 
ATOM   4028 H  H    B SER A 1 260 ? -14.54634 -17.72185 -32.22128 0.757 21.36854 ? 1719 SER A H    1 
ATOM   4029 H  HA   A SER A 1 260 ? -13.40162 -17.88838 -34.55133 0.243 22.39182 ? 1719 SER A HA   1 
ATOM   4030 H  HA   B SER A 1 260 ? -13.43001 -17.91277 -34.54280 0.757 22.63185 ? 1719 SER A HA   1 
ATOM   4031 H  HB2  A SER A 1 260 ? -15.33165 -19.14480 -33.84773 0.243 22.81187 ? 1719 SER A HB2  1 
ATOM   4032 H  HB2  B SER A 1 260 ? -15.37893 -18.71093 -35.28729 0.757 23.71830 ? 1719 SER A HB2  1 
ATOM   4033 H  HB3  A SER A 1 260 ? -16.19880 -17.85321 -34.17221 0.243 22.81187 ? 1719 SER A HB3  1 
ATOM   4034 H  HB3  B SER A 1 260 ? -15.49456 -19.01305 -33.73141 0.757 23.71830 ? 1719 SER A HB3  1 
ATOM   4035 H  HG   A SER A 1 260 ? -14.79973 -19.18407 -35.97602 0.243 23.02348 ? 1719 SER A HG   1 
ATOM   4036 H  HG   B SER A 1 260 ? -16.74391 -17.19038 -33.59027 0.757 24.84580 ? 1719 SER A HG   1 
ATOM   4037 N  N    . GLU A 1 261 ? -14.87774 -15.12611 -34.06463 1.000 19.21022 ? 1720 GLU A N    1 
ATOM   4038 C  CA   . GLU A 1 261 ? -15.06912 -13.77240 -34.55461 1.000 20.20507 ? 1720 GLU A CA   1 
ATOM   4039 C  C    . GLU A 1 261 ? -13.84170 -12.89347 -34.36983 1.000 20.13138 ? 1720 GLU A C    1 
ATOM   4040 O  O    . GLU A 1 261 ? -13.89178 -11.70410 -34.70473 1.000 21.21309 ? 1720 GLU A O    1 
ATOM   4041 C  CB   . GLU A 1 261 ? -16.23975 -13.10772 -33.82951 1.000 21.54997 ? 1720 GLU A CB   1 
ATOM   4042 C  CG   . GLU A 1 261 ? -17.56387 -13.73685 -34.18772 1.000 23.74497 ? 1720 GLU A CG   1 
ATOM   4043 C  CD   . GLU A 1 261 ? -18.71545 -13.24905 -33.33868 1.000 26.11894 ? 1720 GLU A CD   1 
ATOM   4044 O  OE1  . GLU A 1 261 ? -18.49153 -12.45746 -32.40386 1.000 27.20328 ? 1720 GLU A OE1  1 
ATOM   4045 O  OE2  . GLU A 1 261 ? -19.85909 -13.65633 -33.61118 1.000 27.14275 ? 1720 GLU A OE2  1 
ATOM   4046 H  H    . GLU A 1 261 ? -15.12749 -15.22699 -33.24790 1.000 23.05506 ? 1720 GLU A H    1 
ATOM   4047 H  HA   . GLU A 1 261 ? -15.27501 -13.82609 -35.50099 1.000 24.24889 ? 1720 GLU A HA   1 
ATOM   4048 H  HB2  . GLU A 1 261 ? -16.11184 -13.19597 -32.87204 1.000 25.86276 ? 1720 GLU A HB2  1 
ATOM   4049 H  HB3  . GLU A 1 261 ? -16.27407 -12.16982 -34.07459 1.000 25.86276 ? 1720 GLU A HB3  1 
ATOM   4050 H  HG2  . GLU A 1 261 ? -17.76890 -13.52897 -35.11273 1.000 28.49676 ? 1720 GLU A HG2  1 
ATOM   4051 H  HG3  . GLU A 1 261 ? -17.49563 -14.69736 -34.07081 1.000 28.49676 ? 1720 GLU A HG3  1 
ATOM   4052 N  N    . GLY A 1 262 ? -12.76065 -13.43229 -33.81689 1.000 19.16021 ? 1721 GLY A N    1 
ATOM   4053 C  CA   . GLY A 1 262 ? -11.55653 -12.64891 -33.60544 1.000 18.33117 ? 1721 GLY A CA   1 
ATOM   4054 C  C    . GLY A 1 262 ? -11.59854 -11.69095 -32.43513 1.000 17.79952 ? 1721 GLY A C    1 
ATOM   4055 O  O    . GLY A 1 262 ? -10.75891 -10.78218 -32.35877 1.000 19.54447 ? 1721 GLY A O    1 
ATOM   4056 H  H    . GLY A 1 262 ? -12.70128 -14.24968 -33.55624 1.000 22.99505 ? 1721 GLY A H    1 
ATOM   4057 H  HA2  . GLY A 1 262 ? -10.81517 -13.25718 -33.45947 1.000 22.00020 ? 1721 GLY A HA2  1 
ATOM   4058 H  HA3  . GLY A 1 262 ? -11.38429 -12.12721 -34.40485 1.000 22.00020 ? 1721 GLY A HA3  1 
ATOM   4059 N  N    . ARG A 1 263 ? -12.52856 -11.87807 -31.50014 1.000 15.93351 ? 1722 ARG A N    1 
ATOM   4060 C  CA   . ARG A 1 263 ? -12.61971 -10.98490 -30.34462 1.000 15.05183 ? 1722 ARG A CA   1 
ATOM   4061 C  C    . ARG A 1 263 ? -11.57528 -11.28245 -29.28390 1.000 15.15447 ? 1722 ARG A C    1 
ATOM   4062 O  O    . ARG A 1 263 ? -11.20289 -10.38970 -28.51307 1.000 16.86520 ? 1722 ARG A O    1 
ATOM   4063 C  CB   . ARG A 1 263 ? -14.00872 -11.05141 -29.71584 1.000 16.08616 ? 1722 ARG A CB   1 
ATOM   4064 C  CG   . ARG A 1 263 ? -15.10316 -10.76682 -30.69401 1.000 17.10733 ? 1722 ARG A CG   1 
ATOM   4065 C  CD   . ARG A 1 263 ? -16.46839 -10.84228 -30.05627 1.000 18.11009 ? 1722 ARG A CD   1 
ATOM   4066 N  NE   . ARG A 1 263 ? -16.69228 -9.73533  -29.13409 1.000 18.57330 ? 1722 ARG A NE   1 
ATOM   4067 C  CZ   . ARG A 1 263 ? -17.78655 -9.58787  -28.40456 1.000 18.96282 ? 1722 ARG A CZ   1 
ATOM   4068 N  NH1  . ARG A 1 263 ? -18.72950 -10.51218 -28.39363 1.000 19.09705 ? 1722 ARG A NH1  1 
ATOM   4069 N  NH2  . ARG A 1 263 ? -17.93588 -8.48412  -27.67184 1.000 19.41287 ? 1722 ARG A NH2  1 
ATOM   4070 H  H    . ARG A 1 263 ? -13.11378 -12.50817 -31.50981 1.000 19.12301 ? 1722 ARG A H    1 
ATOM   4071 H  HA   . ARG A 1 263 ? -12.47393 -10.08141 -30.66610 1.000 18.06499 ? 1722 ARG A HA   1 
ATOM   4072 H  HB2  . ARG A 1 263 ? -14.15042 -11.94170 -29.35778 1.000 19.30619 ? 1722 ARG A HB2  1 
ATOM   4073 H  HB3  . ARG A 1 263 ? -14.06435 -10.39481 -29.00402 1.000 19.30619 ? 1722 ARG A HB3  1 
ATOM   4074 H  HG2  . ARG A 1 263 ? -14.98603 -9.87321  -31.05268 1.000 20.53160 ? 1722 ARG A HG2  1 
ATOM   4075 H  HG3  . ARG A 1 263 ? -15.06790 -11.41930 -31.41089 1.000 20.53160 ? 1722 ARG A HG3  1 
ATOM   4076 H  HD2  . ARG A 1 263 ? -17.14777 -10.80495 -30.74761 1.000 21.73490 ? 1722 ARG A HD2  1 
ATOM   4077 H  HD3  . ARG A 1 263 ? -16.54514 -11.67229 -29.56018 1.000 21.73490 ? 1722 ARG A HD3  1 
ATOM   4078 H  HE   . ARG A 1 263 ? -16.07486 -9.14132  -29.05961 1.000 22.29076 ? 1722 ARG A HE   1 
ATOM   4079 H  HH11 . ARG A 1 263 ? -18.63836 -11.22504 -28.86599 1.000 22.91925 ? 1722 ARG A HH11 1 
ATOM   4080 H  HH12 . ARG A 1 263 ? -19.43477 -10.40132 -27.91414 1.000 22.91925 ? 1722 ARG A HH12 1 
ATOM   4081 H  HH21 . ARG A 1 263 ? -17.32520 -7.87862  -27.67710 1.000 23.29824 ? 1722 ARG A HH21 1 
ATOM   4082 H  HH22 . ARG A 1 263 ? -18.64290 -8.37764  -27.19394 1.000 23.29824 ? 1722 ARG A HH22 1 
ATOM   4083 N  N    . LEU A 1 264 ? -11.11355 -12.52207 -29.22507 1.000 14.54387 ? 1723 LEU A N    1 
ATOM   4084 C  CA   . LEU A 1 264 ? -9.95911  -12.92599 -28.43917 1.000 14.40964 ? 1723 LEU A CA   1 
ATOM   4085 C  C    . LEU A 1 264 ? -9.40173  -14.15122 -29.14526 1.000 13.54901 ? 1723 LEU A C    1 
ATOM   4086 O  O    . LEU A 1 264 ? -10.04955 -14.72844 -30.02017 1.000 14.01223 ? 1723 LEU A O    1 
ATOM   4087 C  CB   . LEU A 1 264 ? -10.29807 -13.20935 -26.97812 1.000 14.36753 ? 1723 LEU A CB   1 
ATOM   4088 C  CG   . LEU A 1 264 ? -11.04395 -14.50569 -26.64458 1.000 14.31226 ? 1723 LEU A CG   1 
ATOM   4089 C  CD1  . LEU A 1 264 ? -11.15390 -14.61967 -25.11509 1.000 14.95971 ? 1723 LEU A CD1  1 
ATOM   4090 C  CD2  . LEU A 1 264 ? -12.40341 -14.52310 -27.30759 1.000 14.84390 ? 1723 LEU A CD2  1 
ATOM   4091 H  H    . LEU A 1 264 ? -11.46821 -13.17921 -29.65166 1.000 17.45544 ? 1723 LEU A H    1 
ATOM   4092 H  HA   . LEU A 1 264 ? -9.29593  -12.21860 -28.41265 1.000 17.29437 ? 1723 LEU A HA   1 
ATOM   4093 H  HB2  . LEU A 1 264 ? -9.46440  -13.23371 -26.48285 1.000 17.24384 ? 1723 LEU A HB2  1 
ATOM   4094 H  HB3  . LEU A 1 264 ? -10.85250 -12.48030 -26.65876 1.000 17.24384 ? 1723 LEU A HB3  1 
ATOM   4095 H  HG   . LEU A 1 264 ? -10.56353 -15.27769 -26.98239 1.000 17.17751 ? 1723 LEU A HG   1 
ATOM   4096 H  HD11 . LEU A 1 264 ? -11.61758 -15.44200 -24.89221 1.000 17.95445 ? 1723 LEU A HD11 1 
ATOM   4097 H  HD12 . LEU A 1 264 ? -10.26187 -14.62924 -24.73418 1.000 17.95445 ? 1723 LEU A HD12 1 
ATOM   4098 H  HD13 . LEU A 1 264 ? -11.65000 -13.85799 -24.77650 1.000 17.95445 ? 1723 LEU A HD13 1 
ATOM   4099 H  HD21 . LEU A 1 264 ? -12.91826 -15.26476 -26.95294 1.000 17.81548 ? 1723 LEU A HD21 1 
ATOM   4100 H  HD22 . LEU A 1 264 ? -12.85679 -13.68625 -27.12042 1.000 17.81548 ? 1723 LEU A HD22 1 
ATOM   4101 H  HD23 . LEU A 1 264 ? -12.28666 -14.62919 -28.26468 1.000 17.81548 ? 1723 LEU A HD23 1 
ATOM   4102 N  N    . SER A 1 265 ? -8.18444  -14.53305 -28.78994 1.000 12.06463 ? 1724 SER A N    1 
ATOM   4103 C  CA   . SER A 1 265 ? -7.54273  -15.66800 -29.43788 1.000 12.82524 ? 1724 SER A CA   1 
ATOM   4104 C  C    . SER A 1 265 ? -7.81671  -16.96595 -28.67910 1.000 12.03041 ? 1724 SER A C    1 
ATOM   4105 O  O    . SER A 1 265 ? -8.26987  -16.96631 -27.53882 1.000 12.68575 ? 1724 SER A O    1 
ATOM   4106 C  CB   . SER A 1 265 ? -6.03322  -15.44147 -29.52195 1.000 12.88841 ? 1724 SER A CB   1 
ATOM   4107 O  OG   . SER A 1 265 ? -5.47711  -15.50466 -28.21818 1.000 13.26740 ? 1724 SER A OG   1 
ATOM   4108 H  H    . SER A 1 265 ? -7.71142  -14.15391 -28.17994 1.000 14.48035 ? 1724 SER A H    1 
ATOM   4109 H  HA   . SER A 1 265 ? -7.90546  -15.75426 -30.33337 1.000 15.39308 ? 1724 SER A HA   1 
ATOM   4110 H  HB2  . SER A 1 265 ? -5.63449  -16.13072 -30.07589 1.000 15.46889 ? 1724 SER A HB2  1 
ATOM   4111 H  HB3  . SER A 1 265 ? -5.85958  -14.56700 -29.90410 1.000 15.46889 ? 1724 SER A HB3  1 
ATOM   4112 H  HG   . SER A 1 265 ? -4.64676  -15.38283 -28.25380 1.000 15.92368 ? 1724 SER A HG   1 
ATOM   4113 N  N    . LEU A 1 266 ? -7.49112  -18.09663 -29.32234 1.000 12.23043 ? 1725 LEU A N    1 
ATOM   4114 C  CA   . LEU A 1 266 ? -7.58889  -19.37413 -28.62669 1.000 11.65405 ? 1725 LEU A CA   1 
ATOM   4115 C  C    . LEU A 1 266 ? -6.67300  -19.38484 -27.41547 1.000 11.49350 ? 1725 LEU A C    1 
ATOM   4116 O  O    . LEU A 1 266 ? -7.06204  -19.83759 -26.33694 1.000 12.00672 ? 1725 LEU A O    1 
ATOM   4117 C  CB   . LEU A 1 266 ? -7.24628  -20.50911 -29.58381 1.000 13.31214 ? 1725 LEU A CB   1 
ATOM   4118 C  CG   . LEU A 1 266 ? -7.34640  -21.91016 -28.99204 1.000 15.05972 ? 1725 LEU A CG   1 
ATOM   4119 C  CD1  . LEU A 1 266 ? -8.76556  -22.22451 -28.60024 1.000 16.26249 ? 1725 LEU A CD1  1 
ATOM   4120 C  CD2  . LEU A 1 266 ? -6.81995  -22.95160 -29.99054 1.000 15.97299 ? 1725 LEU A CD2  1 
ATOM   4121 H  H    . LEU A 1 266 ? -7.21961  -18.14421 -30.13697 1.000 14.67932 ? 1725 LEU A H    1 
ATOM   4122 H  HA   . LEU A 1 266 ? -8.49863  -19.51396 -28.32057 1.000 13.98766 ? 1725 LEU A HA   1 
ATOM   4123 H  HB2  . LEU A 1 266 ? -7.85572  -20.46773 -30.33732 1.000 15.97737 ? 1725 LEU A HB2  1 
ATOM   4124 H  HB3  . LEU A 1 266 ? -6.33346  -20.38686 -29.88831 1.000 15.97737 ? 1725 LEU A HB3  1 
ATOM   4125 H  HG   . LEU A 1 266 ? -6.80029  -21.95281 -28.19151 1.000 18.07446 ? 1725 LEU A HG   1 
ATOM   4126 H  HD11 . LEU A 1 266 ? -8.82313  -23.15846 -28.34466 1.000 19.51779 ? 1725 LEU A HD11 1 
ATOM   4127 H  HD12 . LEU A 1 266 ? -9.01905  -21.66077 -27.85268 1.000 19.51779 ? 1725 LEU A HD12 1 
ATOM   4128 H  HD13 . LEU A 1 266 ? -9.34761  -22.05213 -29.35681 1.000 19.51779 ? 1725 LEU A HD13 1 
ATOM   4129 H  HD21 . LEU A 1 266 ? -6.88887  -23.83358 -29.59271 1.000 19.17038 ? 1725 LEU A HD21 1 
ATOM   4130 H  HD22 . LEU A 1 266 ? -7.35331  -22.91111 -30.79972 1.000 19.17038 ? 1725 LEU A HD22 1 
ATOM   4131 H  HD23 . LEU A 1 266 ? -5.89290  -22.75254 -30.19512 1.000 19.17038 ? 1725 LEU A HD23 1 
ATOM   4132 N  N    . ASP A 1 267 ? -5.45451  -18.84088 -27.56438 1.000 10.68551 ? 1726 ASP A N    1 
ATOM   4133 C  CA   . ASP A 1 267 ? -4.55753  -18.75880 -26.42619 1.000 10.89870 ? 1726 ASP A CA   1 
ATOM   4134 C  C    . ASP A 1 267 ? -5.16847  -17.92437 -25.30480 1.000 10.26967 ? 1726 ASP A C    1 
ATOM   4135 O  O    . ASP A 1 267 ? -5.08467  -18.28600 -24.13000 1.000 10.39863 ? 1726 ASP A O    1 
ATOM   4136 C  CB   . ASP A 1 267 ? -3.21054  -18.16588 -26.83830 1.000 12.85946 ? 1726 ASP A CB   1 
ATOM   4137 C  CG   . ASP A 1 267 ? -2.32299  -17.92802 -25.65789 1.000 15.40976 ? 1726 ASP A CG   1 
ATOM   4138 O  OD1  . ASP A 1 267 ? -1.93633  -18.92573 -25.03155 1.000 15.34659 ? 1726 ASP A OD1  1 
ATOM   4139 O  OD2  . ASP A 1 267 ? -2.04281  -16.75192 -25.34062 1.000 17.31788 ? 1726 ASP A OD2  1 
ATOM   4140 H  H    . ASP A 1 267 ? -5.13991  -18.52286 -28.29887 1.000 12.82541 ? 1726 ASP A H    1 
ATOM   4141 H  HA   . ASP A 1 267 ? -4.40171  -19.65868 -26.09935 1.000 13.08123 ? 1726 ASP A HA   1 
ATOM   4142 H  HB2  . ASP A 1 267 ? -2.76036  -18.78134 -27.43784 1.000 15.43415 ? 1726 ASP A HB2  1 
ATOM   4143 H  HB3  . ASP A 1 267 ? -3.35784  -17.31686 -27.28370 1.000 15.43415 ? 1726 ASP A HB3  1 
ATOM   4144 N  N    . ASP A 1 268 ? -5.77903  -16.78054 -25.65262 1.000 10.86448 ? 1727 ASP A N    1 
ATOM   4145 C  CA   . ASP A 1 268 ? -6.39015  -15.94614 -24.62519 1.000 11.78301 ? 1727 ASP A CA   1 
ATOM   4146 C  C    . ASP A 1 268 ? -7.41359  -16.75630 -23.82050 1.000 11.23031 ? 1727 ASP A C    1 
ATOM   4147 O  O    . ASP A 1 268 ? -7.49712  -16.64975 -22.59263 1.000 11.28032 ? 1727 ASP A O    1 
ATOM   4148 C  CB   . ASP A 1 268 ? -7.11552  -14.74812 -25.26385 1.000 13.65165 ? 1727 ASP A CB   1 
ATOM   4149 C  CG   . ASP A 1 268 ? -6.19520  -13.70348 -25.89779 1.000 15.03867 ? 1727 ASP A CG   1 
ATOM   4150 O  OD1  . ASP A 1 268 ? -4.99427  -13.59369 -25.56317 1.000 16.48357 ? 1727 ASP A OD1  1 
ATOM   4151 O  OD2  . ASP A 1 268 ? -6.70926  -12.98586 -26.78595 1.000 15.90982 ? 1727 ASP A OD2  1 
ATOM   4152 H  H    . ASP A 1 268 ? -5.84800  -16.47909 -26.45510 1.000 13.04017 ? 1727 ASP A H    1 
ATOM   4153 H  HA   . ASP A 1 268 ? -5.68842  -15.61603 -24.04253 1.000 14.14241 ? 1727 ASP A HA   1 
ATOM   4154 H  HB2  . ASP A 1 268 ? -7.70315  -15.07960 -25.96078 1.000 16.38478 ? 1727 ASP A HB2  1 
ATOM   4155 H  HB3  . ASP A 1 268 ? -7.63451  -14.30055 -24.57739 1.000 16.38478 ? 1727 ASP A HB3  1 
ATOM   4156 N  N    . LEU A 1 269 ? -8.19355  -17.57499 -24.51658 1.000 11.51193 ? 1728 LEU A N    1 
ATOM   4157 C  CA   A LEU A 1 269 ? -9.18846  -18.41495 -23.87122 0.714 12.26728 ? 1728 LEU A CA   1 
ATOM   4158 C  CA   B LEU A 1 269 ? -9.19062  -18.41339 -23.86496 0.286 11.86197 ? 1728 LEU A CA   1 
ATOM   4159 C  C    . LEU A 1 269 ? -8.53769  -19.44766 -22.96339 1.000 11.64352 ? 1728 LEU A C    1 
ATOM   4160 O  O    . LEU A 1 269 ? -8.96771  -19.64028 -21.81779 1.000 12.37255 ? 1728 LEU A O    1 
ATOM   4161 C  CB   A LEU A 1 269 ? -10.02222 -19.06381 -24.96619 0.714 13.18055 ? 1728 LEU A CB   1 
ATOM   4162 C  CB   B LEU A 1 269 ? -10.04511 -19.09119 -24.93174 0.286 12.31465 ? 1728 LEU A CB   1 
ATOM   4163 C  CG   A LEU A 1 269 ? -11.11096 -20.01465 -24.51301 0.714 13.46216 ? 1728 LEU A CG   1 
ATOM   4164 C  CG   B LEU A 1 269 ? -11.22842 -19.92516 -24.45065 0.286 12.43835 ? 1728 LEU A CG   1 
ATOM   4165 C  CD1  A LEU A 1 269 ? -12.05338 -19.28732 -23.60114 0.714 13.57533 ? 1728 LEU A CD1  1 
ATOM   4166 C  CD1  B LEU A 1 269 ? -12.27284 -19.97522 -25.55880 0.286 12.28307 ? 1728 LEU A CD1  1 
ATOM   4167 C  CD2  A LEU A 1 269 ? -11.84337 -20.55018 -25.72474 0.714 13.42268 ? 1728 LEU A CD2  1 
ATOM   4168 C  CD2  B LEU A 1 269 ? -10.82526 -21.33020 -24.03450 0.286 12.48046 ? 1728 LEU A CD2  1 
ATOM   4169 H  H    A LEU A 1 269 ? -8.16575  -17.66306 -25.37161 0.714 13.81711 ? 1728 LEU A H    1 
ATOM   4170 H  H    B LEU A 1 269 ? -8.16610  -17.66493 -25.37143 0.286 13.81711 ? 1728 LEU A H    1 
ATOM   4171 H  HA   A LEU A 1 269 ? -9.77000  -17.88497 -23.30393 0.714 14.72353 ? 1728 LEU A HA   1 
ATOM   4172 H  HA   B LEU A 1 269 ? -9.76481  -17.86192 -23.31081 0.286 14.23716 ? 1728 LEU A HA   1 
ATOM   4173 H  HB2  A LEU A 1 269 ? -10.45302 -18.35829 -25.47370 0.714 15.81945 ? 1728 LEU A HB2  1 
ATOM   4174 H  HB2  B LEU A 1 269 ? -10.40381 -18.39962 -25.50964 0.286 14.78038 ? 1728 LEU A HB2  1 
ATOM   4175 H  HB3  A LEU A 1 269 ? -9.42439  -19.56781 -25.54021 0.714 15.81945 ? 1728 LEU A HB3  1 
ATOM   4176 H  HB3  B LEU A 1 269 ? -9.47063  -19.68410 -25.44098 0.286 14.78038 ? 1728 LEU A HB3  1 
ATOM   4177 H  HG   A LEU A 1 269 ? -10.73239 -20.76472 -24.02828 0.714 16.15739 ? 1728 LEU A HG   1 
ATOM   4178 H  HG   B LEU A 1 269 ? -11.60154 -19.50917 -23.65779 0.286 14.92882 ? 1728 LEU A HG   1 
ATOM   4179 H  HD11 A LEU A 1 269 ? -12.82601 -19.84897 -23.43235 0.714 16.29320 ? 1728 LEU A HD11 1 
ATOM   4180 H  HD11 B LEU A 1 269 ? -13.01642 -20.52569 -25.26730 0.286 14.74248 ? 1728 LEU A HD11 1 
ATOM   4181 H  HD12 A LEU A 1 269 ? -11.59809 -19.09177 -22.76725 0.714 16.29320 ? 1728 LEU A HD12 1 
ATOM   4182 H  HD12 B LEU A 1 269 ? -12.58079 -19.07413 -25.74345 0.286 14.74248 ? 1728 LEU A HD12 1 
ATOM   4183 H  HD13 A LEU A 1 269 ? -12.33144 -18.46172 -24.02770 0.714 16.29320 ? 1728 LEU A HD13 1 
ATOM   4184 H  HD13 B LEU A 1 269 ? -11.87074 -20.35697 -26.35472 0.286 14.74248 ? 1728 LEU A HD13 1 
ATOM   4185 H  HD21 A LEU A 1 269 ? -12.54306 -21.15369 -25.42961 0.714 16.11002 ? 1728 LEU A HD21 1 
ATOM   4186 H  HD21 B LEU A 1 269 ? -11.61470 -21.89361 -24.01862 0.286 14.97935 ? 1728 LEU A HD21 1 
ATOM   4187 H  HD22 A LEU A 1 269 ? -12.23151 -19.80730 -26.21297 0.714 16.11002 ? 1728 LEU A HD22 1 
ATOM   4188 H  HD22 B LEU A 1 269 ? -10.18399 -21.67726 -24.67421 0.286 14.97935 ? 1728 LEU A HD22 1 
ATOM   4189 H  HD23 A LEU A 1 269 ? -11.21392 -21.02471 -26.28999 0.714 16.11002 ? 1728 LEU A HD23 1 
ATOM   4190 H  HD23 B LEU A 1 269 ? -10.42577 -21.29557 -23.15126 0.286 14.97935 ? 1728 LEU A HD23 1 
ATOM   4191 N  N    . LEU A 1 270 ? -7.48002  -20.10571 -23.45520 1.000 11.81196 ? 1729 LEU A N    1 
ATOM   4192 C  CA   . LEU A 1 270 ? -6.83062  -21.15021 -22.68111 1.000 11.69879 ? 1729 LEU A CA   1 
ATOM   4193 C  C    . LEU A 1 270 ? -6.04386  -20.62622 -21.49349 1.000 10.06439 ? 1729 LEU A C    1 
ATOM   4194 O  O    . LEU A 1 270 ? -5.94808  -21.30989 -20.47149 1.000 10.92501 ? 1729 LEU A O    1 
ATOM   4195 C  CB   . LEU A 1 270 ? -6.00209  -22.05386 -23.58025 1.000 13.60428 ? 1729 LEU A CB   1 
ATOM   4196 C  CG   . LEU A 1 270 ? -6.87380  -22.75416 -24.63358 1.000 14.99919 ? 1729 LEU A CG   1 
ATOM   4197 C  CD1  . LEU A 1 270 ? -6.05021  -23.60508 -25.53102 1.000 15.85718 ? 1729 LEU A CD1  1 
ATOM   4198 C  CD2  . LEU A 1 270 ? -7.98447  -23.60956 -23.99147 1.000 16.34671 ? 1729 LEU A CD2  1 
ATOM   4199 H  H    . LEU A 1 270 ? -7.12787  -19.96305 -24.22672 1.000 14.17715 ? 1729 LEU A H    1 
ATOM   4200 H  HA   . LEU A 1 270 ? -7.52518  -21.70797 -22.29721 1.000 14.04135 ? 1729 LEU A HA   1 
ATOM   4201 H  HB2  . LEU A 1 270 ? -5.33425  -21.52167 -24.04033 1.000 16.32794 ? 1729 LEU A HB2  1 
ATOM   4202 H  HB3  . LEU A 1 270 ? -5.56994  -22.73347 -23.03962 1.000 16.32794 ? 1729 LEU A HB3  1 
ATOM   4203 H  HG   . LEU A 1 270 ? -7.29832  -22.05889 -25.16015 1.000 18.00182 ? 1729 LEU A HG   1 
ATOM   4204 H  HD11 . LEU A 1 270 ? -6.62881  -24.02536 -26.18637 1.000 19.03142 ? 1729 LEU A HD11 1 
ATOM   4205 H  HD12 . LEU A 1 270 ? -5.39315  -23.04899 -25.97816 1.000 19.03142 ? 1729 LEU A HD12 1 
ATOM   4206 H  HD13 . LEU A 1 270 ? -5.60353  -24.28346 -25.00074 1.000 19.03142 ? 1729 LEU A HD13 1 
ATOM   4207 H  HD21 . LEU A 1 270 ? -8.49613  -24.04135 -24.69337 1.000 19.61885 ? 1729 LEU A HD21 1 
ATOM   4208 H  HD22 . LEU A 1 270 ? -7.57691  -24.27882 -23.41973 1.000 19.61885 ? 1729 LEU A HD22 1 
ATOM   4209 H  HD23 . LEU A 1 270 ? -8.56278  -23.03409 -23.46679 1.000 19.61885 ? 1729 LEU A HD23 1 
ATOM   4210 N  N    . GLN A 1 271 ? -5.49569  -19.41704 -21.57445 1.000 8.86424  ? 1730 GLN A N    1 
ATOM   4211 C  CA   . GLN A 1 271 ? -4.95131  -18.83324 -20.35789 1.000 9.03795  ? 1730 GLN A CA   1 
ATOM   4212 C  C    . GLN A 1 271 ? -6.03525  -18.68862 -19.30220 1.000 8.50104  ? 1730 GLN A C    1 
ATOM   4213 O  O    . GLN A 1 271 ? -5.82257  -18.95670 -18.12192 1.000 9.55643  ? 1730 GLN A O    1 
ATOM   4214 C  CB   . GLN A 1 271 ? -4.33995  -17.47557 -20.66150 1.000 9.71434  ? 1730 GLN A CB   1 
ATOM   4215 C  CG   . GLN A 1 271 ? -3.19584  -17.51081 -21.64907 1.000 10.67761 ? 1730 GLN A CG   1 
ATOM   4216 C  CD   . GLN A 1 271 ? -2.04305  -18.36429 -21.19755 1.000 10.53023 ? 1730 GLN A CD   1 
ATOM   4217 O  OE1  . GLN A 1 271 ? -1.71166  -18.41530 -20.01479 1.000 11.33559 ? 1730 GLN A OE1  1 
ATOM   4218 N  NE2  . GLN A 1 271 ? -1.43151  -19.05923 -22.14321 1.000 10.87238 ? 1730 GLN A NE2  1 
ATOM   4219 H  H    . GLN A 1 271 ? -5.43033  -18.93883 -22.28624 1.000 10.63989 ? 1730 GLN A H    1 
ATOM   4220 H  HA   . GLN A 1 271 ? -4.25328  -19.41234 -20.01394 1.000 10.84833 ? 1730 GLN A HA   1 
ATOM   4221 H  HB2  . GLN A 1 271 ? -5.02915  -16.90211 -21.03170 1.000 11.66001 ? 1730 GLN A HB2  1 
ATOM   4222 H  HB3  . GLN A 1 271 ? -4.00204  -17.09696 -19.83483 1.000 11.66001 ? 1730 GLN A HB3  1 
ATOM   4223 H  HG2  . GLN A 1 271 ? -3.51894  -17.86886 -22.49067 1.000 12.81594 ? 1730 GLN A HG2  1 
ATOM   4224 H  HG3  . GLN A 1 271 ? -2.86478  -16.60818 -21.77781 1.000 12.81594 ? 1730 GLN A HG3  1 
ATOM   4225 H  HE21 . GLN A 1 271 ? -1.70026  -19.00531 -22.95836 1.000 13.04965 ? 1730 GLN A HE21 1 
ATOM   4226 H  HE22 . GLN A 1 271 ? -0.76533  -19.56478 -21.94263 1.000 13.04965 ? 1730 GLN A HE22 1 
ATOM   4227 N  N    . ARG A 1 272 ? -7.22503  -18.25993 -19.71835 1.000 8.71422  ? 1731 ARG A N    1 
ATOM   4228 C  CA   . ARG A 1 272 ? -8.26271  -17.84796 -18.78202 1.000 8.55368  ? 1731 ARG A CA   1 
ATOM   4229 C  C    . ARG A 1 272 ? -9.12130  -19.01599 -18.29163 1.000 8.20627  ? 1731 ARG A C    1 
ATOM   4230 O  O    . ARG A 1 272 ? -9.72592  -18.88179 -17.22323 1.000 8.52736  ? 1731 ARG A O    1 
ATOM   4231 C  CB   . ARG A 1 272 ? -9.08808  -16.72025 -19.40542 1.000 8.97741  ? 1731 ARG A CB   1 
ATOM   4232 C  CG   . ARG A 1 272 ? -8.26525  -15.43602 -19.51238 1.000 9.43799  ? 1731 ARG A CG   1 
ATOM   4233 C  CD   . ARG A 1 272 ? -8.86218  -14.38225 -20.40208 1.000 9.70645  ? 1731 ARG A CD   1 
ATOM   4234 N  NE   . ARG A 1 272 ? -8.05100  -13.16660 -20.39924 1.000 10.26967 ? 1731 ARG A NE   1 
ATOM   4235 C  CZ   . ARG A 1 272 ? -6.87125  -13.06201 -20.99013 1.000 11.39086 ? 1731 ARG A CZ   1 
ATOM   4236 N  NH1  . ARG A 1 272 ? -6.41257  -14.00846 -21.78518 1.000 12.26728 ? 1731 ARG A NH1  1 
ATOM   4237 N  NH2  . ARG A 1 272 ? -6.13659  -11.96609 -20.79463 1.000 12.63311 ? 1731 ARG A NH2  1 
ATOM   4238 H  H    . ARG A 1 272 ? -7.45592  -18.19860 -20.54450 1.000 10.45986 ? 1731 ARG A H    1 
ATOM   4239 H  HA   . ARG A 1 272 ? -7.87050  -17.47256 -17.97819 1.000 10.26721 ? 1731 ARG A HA   1 
ATOM   4240 H  HB2  . ARG A 1 272 ? -9.36954  -16.98091 -20.29634 1.000 10.77569 ? 1731 ARG A HB2  1 
ATOM   4241 H  HB3  . ARG A 1 272 ? -9.86401  -16.54369 -18.85074 1.000 10.77569 ? 1731 ARG A HB3  1 
ATOM   4242 H  HG2  . ARG A 1 272 ? -8.17442  -15.05214 -18.62621 1.000 11.32839 ? 1731 ARG A HG2  1 
ATOM   4243 H  HG3  . ARG A 1 272 ? -7.39089  -15.65768 -19.86912 1.000 11.32839 ? 1731 ARG A HG3  1 
ATOM   4244 H  HD2  . ARG A 1 272 ? -8.90921  -14.71700 -21.31127 1.000 11.65053 ? 1731 ARG A HD2  1 
ATOM   4245 H  HD3  . ARG A 1 272 ? -9.75096  -14.15818 -20.08466 1.000 11.65053 ? 1731 ARG A HD3  1 
ATOM   4246 H  HE   . ARG A 1 272 ? -8.35915  -12.47679 -19.98839 1.000 12.32641 ? 1731 ARG A HE   1 
ATOM   4247 H  HH11 . ARG A 1 272 ? -6.88278  -14.71386 -21.92978 1.000 14.72353 ? 1731 ARG A HH11 1 
ATOM   4248 H  HH12 . ARG A 1 272 ? -5.64317  -13.92041 -22.15918 1.000 14.72353 ? 1731 ARG A HH12 1 
ATOM   4249 H  HH21 . ARG A 1 272 ? -6.43063  -11.33592 -20.28864 1.000 15.16253 ? 1731 ARG A HH21 1 
ATOM   4250 H  HH22 . ARG A 1 272 ? -5.36887  -11.88964 -21.17456 1.000 15.16253 ? 1731 ARG A HH22 1 
ATOM   4251 N  N    . LEU A 1 273 ? -9.12384  -20.15111 -19.00508 1.000 9.04584  ? 1732 LEU A N    1 
ATOM   4252 C  CA   . LEU A 1 273 ? -9.88720  -21.31790 -18.57525 1.000 9.08006  ? 1732 LEU A CA   1 
ATOM   4253 C  C    . LEU A 1 273 ? -9.01034  -22.51024 -18.23129 1.000 8.94846  ? 1732 LEU A C    1 
ATOM   4254 O  O    . LEU A 1 273 ? -9.53032  -23.58607 -17.96748 1.000 9.82225  ? 1732 LEU A O    1 
ATOM   4255 C  CB   . LEU A 1 273 ? -10.96721 -21.70820 -19.60103 1.000 10.24335 ? 1732 LEU A CB   1 
ATOM   4256 C  CG   . LEU A 1 273 ? -12.26034 -20.90852 -19.51263 1.000 12.03567 ? 1732 LEU A CG   1 
ATOM   4257 C  CD1  . LEU A 1 273 ? -13.19487 -21.27795 -20.66269 1.000 13.81746 ? 1732 LEU A CD1  1 
ATOM   4258 C  CD2  . LEU A 1 273 ? -12.95220 -21.12494 -18.18976 1.000 11.59088 ? 1732 LEU A CD2  1 
ATOM   4259 H  H    . LEU A 1 273 ? -8.69024  -20.26369 -19.73920 1.000 10.85780 ? 1732 LEU A H    1 
ATOM   4260 H  HA   . LEU A 1 273 ? -10.36054 -21.06948 -17.76585 1.000 10.89887 ? 1732 LEU A HA   1 
ATOM   4261 H  HB2  . LEU A 1 273 ? -10.60483 -21.57831 -20.49137 1.000 12.29482 ? 1732 LEU A HB2  1 
ATOM   4262 H  HB3  . LEU A 1 273 ? -11.19272 -22.64214 -19.46762 1.000 12.29482 ? 1732 LEU A HB3  1 
ATOM   4263 H  HG   . LEU A 1 273 ? -12.04129 -19.96597 -19.57984 1.000 14.44560 ? 1732 LEU A HG   1 
ATOM   4264 H  HD11 . LEU A 1 273 ? -13.99789 -20.73709 -20.60328 1.000 16.58375 ? 1732 LEU A HD11 1 
ATOM   4265 H  HD12 . LEU A 1 273 ? -12.74295 -21.10780 -21.50395 1.000 16.58375 ? 1732 LEU A HD12 1 
ATOM   4266 H  HD13 . LEU A 1 273 ? -13.42350 -22.21814 -20.59428 1.000 16.58375 ? 1732 LEU A HD13 1 
ATOM   4267 H  HD21 . LEU A 1 273 ? -13.87189 -20.82511 -18.26160 1.000 13.91186 ? 1732 LEU A HD21 1 
ATOM   4268 H  HD22 . LEU A 1 273 ? -12.92839 -22.06983 -17.97178 1.000 13.91186 ? 1732 LEU A HD22 1 
ATOM   4269 H  HD23 . LEU A 1 273 ? -12.49082 -20.61579 -17.50506 1.000 13.91186 ? 1732 LEU A HD23 1 
ATOM   4270 N  N    . HIS A 1 274 ? -7.69135  -22.34888 -18.18394 1.000 9.38799  ? 1733 HIS A N    1 
ATOM   4271 C  CA   . HIS A 1 274 ? -6.81761  -23.47745 -17.87653 1.000 9.61696  ? 1733 HIS A CA   1 
ATOM   4272 C  C    . HIS A 1 274 ? -5.57490  -23.02094 -17.12016 1.000 9.04584  ? 1733 HIS A C    1 
ATOM   4273 O  O    . HIS A 1 274 ? -5.43809  -23.32061 -15.93532 1.000 10.14597 ? 1733 HIS A O    1 
ATOM   4274 C  CB   . HIS A 1 274 ? -6.49056  -24.22114 -19.17103 1.000 9.91173  ? 1733 HIS A CB   1 
ATOM   4275 C  CG   . HIS A 1 274 ? -5.59876  -25.40878 -18.98359 1.000 9.89331  ? 1733 HIS A CG   1 
ATOM   4276 N  ND1  . HIS A 1 274 ? -6.02567  -26.59875 -18.43200 1.000 10.42232 ? 1733 HIS A ND1  1 
ATOM   4277 C  CD2  . HIS A 1 274 ? -4.28283  -25.57873 -19.26227 1.000 10.80131 ? 1733 HIS A CD2  1 
ATOM   4278 C  CE1  . HIS A 1 274 ? -5.01010  -27.44229 -18.38451 1.000 10.89080 ? 1733 HIS A CE1  1 
ATOM   4279 N  NE2  . HIS A 1 274 ? -3.94057  -26.85234 -18.88363 1.000 11.29348 ? 1733 HIS A NE2  1 
ATOM   4280 H  H    . HIS A 1 274 ? -7.28251  -21.60539 -18.32420 1.000 11.26838 ? 1733 HIS A H    1 
ATOM   4281 H  HA   . HIS A 1 274 ? -7.26256  -24.10558 -17.28629 1.000 11.54315 ? 1733 HIS A HA   1 
ATOM   4282 H  HB2  . HIS A 1 274 ? -7.31874  -24.53399 -19.56743 1.000 11.89688 ? 1733 HIS A HB2  1 
ATOM   4283 H  HB3  . HIS A 1 274 ? -6.04334  -23.60928 -19.77645 1.000 11.89688 ? 1733 HIS A HB3  1 
ATOM   4284 H  HD1  . HIS A 1 274 ? -6.82514  -26.76497 -18.16215 1.000 12.50958 ? 1733 HIS A HD1  1 
ATOM   4285 H  HD2  . HIS A 1 274 ? -3.71531  -24.94688 -19.64121 1.000 12.96437 ? 1733 HIS A HD2  1 
ATOM   4286 H  HE1  . HIS A 1 274 ? -5.04354  -28.31063 -18.05320 1.000 13.07176 ? 1733 HIS A HE1  1 
ATOM   4287 N  N    . HIS A 1 275 ? -4.68531  -22.25773 -17.76754 1.000 9.21692  ? 1734 HIS A N    1 
ATOM   4288 C  CA   . HIS A 1 275 ? -3.39702  -21.99066 -17.14082 1.000 9.43010  ? 1734 HIS A CA   1 
ATOM   4289 C  C    . HIS A 1 275 ? -3.50590  -21.07393 -15.92684 1.000 9.76435  ? 1734 HIS A C    1 
ATOM   4290 O  O    . HIS A 1 275 ? -2.87050  -21.31815 -14.89100 1.000 10.16966 ? 1734 HIS A O    1 
ATOM   4291 C  CB   . HIS A 1 275 ? -2.45388  -21.36436 -18.16185 1.000 9.99069  ? 1734 HIS A CB   1 
ATOM   4292 C  CG   . HIS A 1 275 ? -1.96528  -22.32703 -19.17833 1.000 10.33021 ? 1734 HIS A CG   1 
ATOM   4293 N  ND1  . HIS A 1 275 ? -1.13953  -23.38293 -18.85260 1.000 10.48549 ? 1734 HIS A ND1  1 
ATOM   4294 C  CD2  . HIS A 1 275 ? -2.16917  -22.39610 -20.50842 1.000 11.36191 ? 1734 HIS A CD2  1 
ATOM   4295 C  CE1  . HIS A 1 275 ? -0.86309  -24.06274 -19.94481 1.000 11.84618 ? 1734 HIS A CE1  1 
ATOM   4296 N  NE2  . HIS A 1 275 ? -1.47357  -23.48498 -20.95701 1.000 12.24096 ? 1734 HIS A NE2  1 
ATOM   4297 H  H    . HIS A 1 275 ? -4.80298  -21.89880 -18.54015 1.000 11.06310 ? 1734 HIS A H    1 
ATOM   4298 H  HA   . HIS A 1 275 ? -3.03822  -22.83888 -16.83639 1.000 11.31892 ? 1734 HIS A HA   1 
ATOM   4299 H  HB2  . HIS A 1 275 ? -2.92220  -20.65304 -18.62619 1.000 11.99163 ? 1734 HIS A HB2  1 
ATOM   4300 H  HB3  . HIS A 1 275 ? -1.68220  -21.00509 -17.69673 1.000 11.99163 ? 1734 HIS A HB3  1 
ATOM   4301 H  HD1  . HIS A 1 275 ? -0.85191  -23.56712 -18.06333 1.000 12.58539 ? 1734 HIS A HD1  1 
ATOM   4302 H  HD2  . HIS A 1 275 ? -2.68332  -21.81577 -21.02201 1.000 13.63709 ? 1734 HIS A HD2  1 
ATOM   4303 H  HE1  . HIS A 1 275 ? -0.32780  -24.82172 -19.99302 1.000 14.21821 ? 1734 HIS A HE1  1 
ATOM   4304 N  N    . ASN A 1 276 ? -4.28377  -20.00277 -16.02692 1.000 9.35904  ? 1735 ASN A N    1 
ATOM   4305 C  CA   . ASN A 1 276 ? -4.34592  -19.08019 -14.89938 1.000 9.50379  ? 1735 ASN A CA   1 
ATOM   4306 C  C    . ASN A 1 276 ? -5.15409  -19.65180 -13.73317 1.000 9.30640  ? 1735 ASN A C    1 
ATOM   4307 O  O    . ASN A 1 276 ? -4.75640  -19.49044 -12.58052 1.000 9.76435  ? 1735 ASN A O    1 
ATOM   4308 C  CB   . ASN A 1 276 ? -4.84739  -17.68805 -15.31141 1.000 9.40641  ? 1735 ASN A CB   1 
ATOM   4309 C  CG   . ASN A 1 276 ? -3.85404  -16.95300 -16.17684 1.000 10.65656 ? 1735 ASN A CG   1 
ATOM   4310 O  OD1  . ASN A 1 276 ? -2.63754  -17.19595 -16.06912 1.000 11.54351 ? 1735 ASN A OD1  1 
ATOM   4311 N  ND2  . ASN A 1 276 ? -4.31079  -16.00573 -16.96022 1.000 10.30389 ? 1735 ASN A ND2  1 
ATOM   4312 H  H    . ASN A 1 276 ? -4.76551  -19.79630 -16.70876 1.000 11.23364 ? 1735 ASN A H    1 
ATOM   4313 H  HA   . ASN A 1 276 ? -3.43924  -18.96579 -14.57421 1.000 11.40735 ? 1735 ASN A HA   1 
ATOM   4314 H  HB2  . ASN A 1 276 ? -5.67211  -17.78318 -15.81309 1.000 11.29049 ? 1735 ASN A HB2  1 
ATOM   4315 H  HB3  . ASN A 1 276 ? -5.00326  -17.15784 -14.51424 1.000 11.29049 ? 1735 ASN A HB3  1 
ATOM   4316 H  HD21 . ASN A 1 276 ? -5.15095  -15.82226 -16.96831 1.000 12.36746 ? 1735 ASN A HD21 1 
ATOM   4317 H  HD22 . ASN A 1 276 ? -3.77017  -15.56797 -17.46589 1.000 12.36746 ? 1735 ASN A HD22 1 
ATOM   4318 N  N    . PRO A 1 277 ? -6.27675  -20.35626 -13.96985 1.000 9.17744  ? 1736 PRO A N    1 
ATOM   4319 C  CA   . PRO A 1 277 ? -6.90152  -21.07985 -12.85216 1.000 10.18019 ? 1736 PRO A CA   1 
ATOM   4320 C  C    . PRO A 1 277 ? -5.92797  -21.99410 -12.13318 1.000 10.08807 ? 1736 PRO A C    1 
ATOM   4321 O  O    . PRO A 1 277 ? -5.88705  -22.01296 -10.89772 1.000 10.62498 ? 1736 PRO A O    1 
ATOM   4322 C  CB   . PRO A 1 277 ? -8.03651  -21.85104 -13.53473 1.000 10.80394 ? 1736 PRO A CB   1 
ATOM   4323 C  CG   . PRO A 1 277 ? -8.44862  -20.96802 -14.65216 1.000 9.85647  ? 1736 PRO A CG   1 
ATOM   4324 C  CD   . PRO A 1 277 ? -7.12531  -20.36350 -15.18012 1.000 9.42747  ? 1736 PRO A CD   1 
ATOM   4325 H  HA   . PRO A 1 277 ? -7.28639  -20.45300 -12.21983 1.000 12.21902 ? 1736 PRO A HA   1 
ATOM   4326 H  HB2  . PRO A 1 277 ? -7.71092  -22.70369 -13.86317 1.000 12.96753 ? 1736 PRO A HB2  1 
ATOM   4327 H  HB3  . PRO A 1 277 ? -8.76646  -21.99232 -12.91174 1.000 12.96753 ? 1736 PRO A HB3  1 
ATOM   4328 H  HG2  . PRO A 1 277 ? -8.89270  -21.48802 -15.34013 1.000 11.83056 ? 1736 PRO A HG2  1 
ATOM   4329 H  HG3  . PRO A 1 277 ? -9.04249  -20.27407 -14.32559 1.000 11.83056 ? 1736 PRO A HG3  1 
ATOM   4330 H  HD2  . PRO A 1 277 ? -6.73921  -20.92107 -15.87362 1.000 11.31576 ? 1736 PRO A HD2  1 
ATOM   4331 H  HD3  . PRO A 1 277 ? -7.26215  -19.46373 -15.51569 1.000 11.31576 ? 1736 PRO A HD3  1 
ATOM   4332 N  N    . ARG A 1 278 ? -5.13347  -22.75976 -12.88974 1.000 9.66960  ? 1737 ARG A N    1 
ATOM   4333 C  CA   . ARG A 1 278 ? -4.14604  -23.62979 -12.26201 1.000 10.55128 ? 1737 ARG A CA   1 
ATOM   4334 C  C    . ARG A 1 278 ? -3.23691  -22.83752 -11.33903 1.000 9.94069  ? 1737 ARG A C    1 
ATOM   4335 O  O    . ARG A 1 278 ? -2.95200  -23.26198 -10.21362 1.000 10.53812 ? 1737 ARG A O    1 
ATOM   4336 C  CB   . ARG A 1 278 ? -3.26257  -24.29141 -13.31446 1.000 11.76722 ? 1737 ARG A CB   1 
ATOM   4337 C  CG   . ARG A 1 278 ? -3.71979  -25.56949 -13.92196 1.000 12.23833 ? 1737 ARG A CG   1 
ATOM   4338 C  CD   . ARG A 1 278 ? -2.65875  -26.05052 -14.88820 1.000 12.84630 ? 1737 ARG A CD   1 
ATOM   4339 N  NE   . ARG A 1 278 ? -2.96776  -27.33593 -15.49792 1.000 12.93315 ? 1737 ARG A NE   1 
ATOM   4340 C  CZ   . ARG A 1 278 ? -2.20630  -27.86178 -16.43535 1.000 12.54626 ? 1737 ARG A CZ   1 
ATOM   4341 N  NH1  . ARG A 1 278 ? -1.14159  -27.21514 -16.88824 1.000 12.13832 ? 1737 ARG A NH1  1 
ATOM   4342 N  NH2  . ARG A 1 278 ? -2.48804  -29.07111 -16.90697 1.000 13.05948 ? 1737 ARG A NH2  1 
ATOM   4343 H  H    . ARG A 1 278 ? -5.14871  -22.79051 -13.74905 1.000 11.60632 ? 1737 ARG A H    1 
ATOM   4344 H  HA   . ARG A 1 278 ? -4.63068  -24.30836 -11.76646 1.000 12.66434 ? 1737 ARG A HA   1 
ATOM   4345 H  HB2  . ARG A 1 278 ? -3.15470  -23.66206 -14.04465 1.000 14.12346 ? 1737 ARG A HB2  1 
ATOM   4346 H  HB3  . ARG A 1 278 ? -2.40294  -24.47336 -12.90358 1.000 14.12346 ? 1737 ARG A HB3  1 
ATOM   4347 H  HG2  . ARG A 1 278 ? -3.84694  -26.23893 -13.23161 1.000 14.68879 ? 1737 ARG A HG2  1 
ATOM   4348 H  HG3  . ARG A 1 278 ? -4.54905  -25.42983 -14.40541 1.000 14.68879 ? 1737 ARG A HG3  1 
ATOM   4349 H  HD2  . ARG A 1 278 ? -2.56547  -25.39912 -15.60085 1.000 15.41835 ? 1737 ARG A HD2  1 
ATOM   4350 H  HD3  . ARG A 1 278 ? -1.81923  -26.14284 -14.41114 1.000 15.41835 ? 1737 ARG A HD3  1 
ATOM   4351 H  HE   . ARG A 1 278 ? -3.66718  -27.76401 -15.23875 1.000 15.52258 ? 1737 ARG A HE   1 
ATOM   4352 H  HH11 . ARG A 1 278 ? -0.94036  -26.44203 -16.56979 1.000 14.56878 ? 1737 ARG A HH11 1 
ATOM   4353 H  HH12 . ARG A 1 278 ? -0.65202  -27.56868 -17.50055 1.000 14.56878 ? 1737 ARG A HH12 1 
ATOM   4354 H  HH21 . ARG A 1 278 ? -3.16393  -29.50553 -16.60029 1.000 15.67417 ? 1737 ARG A HH21 1 
ATOM   4355 H  HH22 . ARG A 1 278 ? -1.99458  -29.41967 -17.51901 1.000 15.67417 ? 1737 ARG A HH22 1 
ATOM   4356 N  N    . ARG A 1 279 ? -2.69877  -21.71459 -11.82604 1.000 9.75645  ? 1738 ARG A N    1 
ATOM   4357 C  CA   . ARG A 1 279 ? -1.61199  -21.07071 -11.11114 1.000 9.49063  ? 1738 ARG A CA   1 
ATOM   4358 C  C    . ARG A 1 279 ? -2.08591  -20.20732 -9.95085  1.000 9.73277  ? 1738 ARG A C    1 
ATOM   4359 O  O    . ARG A 1 279 ? -1.36410  -20.06757 -8.95287  1.000 10.40127 ? 1738 ARG A O    1 
ATOM   4360 C  CB   . ARG A 1 279 ? -0.71903  -20.26064 -12.05522 1.000 9.51695  ? 1738 ARG A CB   1 
ATOM   4361 C  CG   . ARG A 1 279 ? -1.24568  -18.92867 -12.48266 1.000 10.23546 ? 1738 ARG A CG   1 
ATOM   4362 C  CD   . ARG A 1 279 ? -0.41205  -18.38548 -13.64509 1.000 11.78038 ? 1738 ARG A CD   1 
ATOM   4363 N  NE   . ARG A 1 279 ? -0.69336  -16.99615 -13.96692 1.000 13.63587 ? 1738 ARG A NE   1 
ATOM   4364 C  CZ   . ARG A 1 279 ? -0.20362  -15.95101 -13.31938 1.000 17.05206 ? 1738 ARG A CZ   1 
ATOM   4365 N  NH1  . ARG A 1 279 ? 0.61989   -16.09481 -12.28579 1.000 16.82835 ? 1738 ARG A NH1  1 
ATOM   4366 N  NH2  . ARG A 1 279 ? -0.52269  -14.72868 -13.73436 1.000 19.38918 ? 1738 ARG A NH2  1 
ATOM   4367 H  H    . ARG A 1 279 ? -2.94345  -21.32086 -12.55041 1.000 11.71054 ? 1738 ARG A H    1 
ATOM   4368 H  HA   . ARG A 1 279 ? -1.06037  -21.77588 -10.73783 1.000 11.39156 ? 1738 ARG A HA   1 
ATOM   4369 H  HB2  . ARG A 1 279 ? 0.12772   -20.10299 -11.60904 1.000 11.42314 ? 1738 ARG A HB2  1 
ATOM   4370 H  HB3  . ARG A 1 279 ? -0.57768  -20.78334 -12.86002 1.000 11.42314 ? 1738 ARG A HB3  1 
ATOM   4371 H  HG2  . ARG A 1 279 ? -2.16600  -19.01943 -12.77539 1.000 12.28535 ? 1738 ARG A HG2  1 
ATOM   4372 H  HG3  . ARG A 1 279 ? -1.19296  -18.30339 -11.74297 1.000 12.28535 ? 1738 ARG A HG3  1 
ATOM   4373 H  HD2  . ARG A 1 279 ? 0.52758   -18.45091 -13.41331 1.000 14.13925 ? 1738 ARG A HD2  1 
ATOM   4374 H  HD3  . ARG A 1 279 ? -0.59625  -18.91545 -14.43635 1.000 14.13925 ? 1738 ARG A HD3  1 
ATOM   4375 H  HE   . ARG A 1 279 ? -1.21898  -16.84128 -14.62975 1.000 16.36584 ? 1738 ARG A HE   1 
ATOM   4376 H  HH11 . ARG A 1 279 ? 0.84666   -16.88161 -12.02290 1.000 20.19682 ? 1738 ARG A HH11 1 
ATOM   4377 H  HH12 . ARG A 1 279 ? 0.92588   -15.40104 -11.88002 1.000 20.19682 ? 1738 ARG A HH12 1 
ATOM   4378 H  HH21 . ARG A 1 279 ? -1.03989  -14.62660 -14.41383 1.000 23.26982 ? 1738 ARG A HH21 1 
ATOM   4379 H  HH22 . ARG A 1 279 ? -0.21186  -14.04021 -13.32327 1.000 23.26982 ? 1738 ARG A HH22 1 
ATOM   4380 N  N    . ILE A 1 280 ? -3.30015  -19.65656 -10.04462 1.000 9.81962  ? 1739 ILE A N    1 
ATOM   4381 C  CA   . ILE A 1 280 ? -3.81611  -18.82429 -8.96594  1.000 10.05912 ? 1739 ILE A CA   1 
ATOM   4382 C  C    . ILE A 1 280 ? -4.26143  -19.67605 -7.79954  1.000 10.54865 ? 1739 ILE A C    1 
ATOM   4383 O  O    . ILE A 1 280 ? -4.08499  -19.30789 -6.63973  1.000 12.31728 ? 1739 ILE A O    1 
ATOM   4384 C  CB   . ILE A 1 280 ? -4.94301  -17.92158 -9.50047  1.000 10.69078 ? 1739 ILE A CB   1 
ATOM   4385 C  CG1  . ILE A 1 280 ? -4.38711  -16.91232 -10.51655 1.000 11.74353 ? 1739 ILE A CG1  1 
ATOM   4386 C  CG2  . ILE A 1 280 ? -5.69216  -17.25149 -8.34366  1.000 11.29085 ? 1739 ILE A CG2  1 
ATOM   4387 C  CD1  . ILE A 1 280 ? -5.46766  -16.27309 -11.36361 1.000 12.33308 ? 1739 ILE A CD1  1 
ATOM   4388 H  H    . ILE A 1 280 ? -3.83337  -19.75009 -10.71285 1.000 11.78634 ? 1739 ILE A H    1 
ATOM   4389 H  HA   . ILE A 1 280 ? -3.10631  -18.24789 -8.64212  1.000 12.07374 ? 1739 ILE A HA   1 
ATOM   4390 H  HB   . ILE A 1 280 ? -5.58954  -18.46865 -9.97334  1.000 12.83173 ? 1739 ILE A HB   1 
ATOM   4391 H  HG12 . ILE A 1 280 ? -3.92407  -16.20650 -10.03872 1.000 14.09504 ? 1739 ILE A HG12 1 
ATOM   4392 H  HG13 . ILE A 1 280 ? -3.77177  -17.36967 -11.11076 1.000 14.09504 ? 1739 ILE A HG13 1 
ATOM   4393 H  HG21 . ILE A 1 280 ? -6.23118  -16.52554 -8.69489  1.000 13.55181 ? 1739 ILE A HG21 1 
ATOM   4394 H  HG22 . ILE A 1 280 ? -6.26181  -17.90840 -7.91369  1.000 13.55181 ? 1739 ILE A HG22 1 
ATOM   4395 H  HG23 . ILE A 1 280 ? -5.04665  -16.90626 -7.70724  1.000 13.55181 ? 1739 ILE A HG23 1 
ATOM   4396 H  HD11 . ILE A 1 280 ? -5.05090  -15.71528 -12.03894 1.000 14.80249 ? 1739 ILE A HD11 1 
ATOM   4397 H  HD12 . ILE A 1 280 ? -5.99068  -16.97119 -11.78788 1.000 14.80249 ? 1739 ILE A HD12 1 
ATOM   4398 H  HD13 . ILE A 1 280 ? -6.03735  -15.73291 -10.79390 1.000 14.80249 ? 1739 ILE A HD13 1 
ATOM   4399 N  N    . PHE A 1 281 ? -4.84752  -20.83732 -8.09040  1.000 10.33021 ? 1740 PHE A N    1 
ATOM   4400 C  CA   . PHE A 1 281 ? -5.40382  -21.71347 -7.07796  1.000 10.58550 ? 1740 PHE A CA   1 
ATOM   4401 C  C    . PHE A 1 281 ? -4.51399  -22.90407 -6.78910  1.000 11.03555 ? 1740 PHE A C    1 
ATOM   4402 O  O    . PHE A 1 281 ? -4.84698  -23.70585 -5.92281  1.000 12.03304 ? 1740 PHE A O    1 
ATOM   4403 C  CB   . PHE A 1 281 ? -6.81379  -22.15597 -7.49674  1.000 10.56708 ? 1740 PHE A CB   1 
ATOM   4404 C  CG   . PHE A 1 281 ? -7.77285  -21.01282 -7.51998  1.000 10.51707 ? 1740 PHE A CG   1 
ATOM   4405 C  CD1  . PHE A 1 281 ? -8.46029  -20.65329 -6.37619  1.000 11.60404 ? 1740 PHE A CD1  1 
ATOM   4406 C  CD2  . PHE A 1 281 ? -7.91841  -20.24076 -8.66546  1.000 10.86974 ? 1740 PHE A CD2  1 
ATOM   4407 C  CE1  . PHE A 1 281 ? -9.29690  -19.54501 -6.38799  1.000 12.63311 ? 1740 PHE A CE1  1 
ATOM   4408 C  CE2  . PHE A 1 281 ? -8.75897  -19.13182 -8.67642  1.000 11.31453 ? 1740 PHE A CE2  1 
ATOM   4409 C  CZ   . PHE A 1 281 ? -9.42699  -18.78723 -7.53841  1.000 12.08305 ? 1740 PHE A CZ   1 
ATOM   4410 H  H    . PHE A 1 281 ? -4.93414  -21.14171 -8.89006  1.000 12.39905 ? 1740 PHE A H    1 
ATOM   4411 H  HA   . PHE A 1 281 ? -5.49895  -21.23001 -6.24242  1.000 12.70540 ? 1740 PHE A HA   1 
ATOM   4412 H  HB2  . PHE A 1 281 ? -6.77648  -22.53934 -8.38699  1.000 12.68329 ? 1740 PHE A HB2  1 
ATOM   4413 H  HB3  . PHE A 1 281 ? -7.14195  -22.81504 -6.86520  1.000 12.68329 ? 1740 PHE A HB3  1 
ATOM   4414 H  HD1  . PHE A 1 281 ? -8.36255  -21.15372 -5.59842  1.000 13.92765 ? 1740 PHE A HD1  1 
ATOM   4415 H  HD2  . PHE A 1 281 ? -7.44809  -20.46788 -9.43495  1.000 13.04649 ? 1740 PHE A HD2  1 
ATOM   4416 H  HE1  . PHE A 1 281 ? -9.77013  -19.31190 -5.62208  1.000 15.16253 ? 1740 PHE A HE1  1 
ATOM   4417 H  HE2  . PHE A 1 281 ? -8.86422  -18.63033 -9.45252  1.000 13.58024 ? 1740 PHE A HE2  1 
ATOM   4418 H  HZ   . PHE A 1 281 ? -9.97508  -18.03591 -7.53559  1.000 14.50245 ? 1740 PHE A HZ   1 
ATOM   4419 N  N    . HIS A 1 282 ? -3.36453  -22.99202 -7.45212  1.000 10.85395 ? 1741 HIS A N    1 
ATOM   4420 C  CA   . HIS A 1 282 ? -2.45778  -24.14213 -7.32062  1.000 10.37495 ? 1741 HIS A CA   1 
ATOM   4421 C  C    . HIS A 1 282 ? -3.26357  -25.43823 -7.47930  1.000 10.53550 ? 1741 HIS A C    1 
ATOM   4422 O  O    . HIS A 1 282 ? -3.24858  -26.34989 -6.63413  1.000 11.82775 ? 1741 HIS A O    1 
ATOM   4423 C  CB   . HIS A 1 282 ? -1.67731  -24.07252 -5.99835  1.000 11.94882 ? 1741 HIS A CB   1 
ATOM   4424 C  CG   . HIS A 1 282 ? -0.64538  -22.95665 -5.99724  1.000 14.98076 ? 1741 HIS A CG   1 
ATOM   4425 N  ND1  . HIS A 1 282 ? 0.54518   -23.04001 -6.67579  1.000 17.14155 ? 1741 HIS A ND1  1 
ATOM   4426 C  CD2  . HIS A 1 282 ? -0.62204  -21.74569 -5.39100  1.000 15.81507 ? 1741 HIS A CD2  1 
ATOM   4427 C  CE1  . HIS A 1 282 ? 1.24714   -21.93829 -6.51624  1.000 18.29958 ? 1741 HIS A CE1  1 
ATOM   4428 N  NE2  . HIS A 1 282 ? 0.56532   -21.13675 -5.72603  1.000 17.77583 ? 1741 HIS A NE2  1 
ATOM   4429 H  H    . HIS A 1 282 ? -3.07774  -22.39015 -7.99535  1.000 13.02754 ? 1741 HIS A H    1 
ATOM   4430 H  HA   . HIS A 1 282 ? -1.78965  -24.13018 -8.02373  1.000 12.45274 ? 1741 HIS A HA   1 
ATOM   4431 H  HB2  . HIS A 1 282 ? -2.29836  -23.91086 -5.27099  1.000 14.34138 ? 1741 HIS A HB2  1 
ATOM   4432 H  HB3  . HIS A 1 282 ? -1.21395  -24.91311 -5.85831  1.000 14.34138 ? 1741 HIS A HB3  1 
ATOM   4433 H  HD2  . HIS A 1 282 ? -1.28758  -21.39043 -4.84717  1.000 18.98089 ? 1741 HIS A HD2  1 
ATOM   4434 H  HE1  . HIS A 1 282 ? 2.07737   -21.75823 -6.89464  1.000 21.96229 ? 1741 HIS A HE1  1 
ATOM   4435 H  HE2  . HIS A 1 282 ? 0.82038   -20.35902 -5.46205  1.000 21.33380 ? 1741 HIS A HE2  1 
ATOM   4436 N  N    . LEU A 1 283 ? -3.99594  -25.49877 -8.58099  1.000 11.11977 ? 1742 LEU A N    1 
ATOM   4437 C  CA   . LEU A 1 283 ? -4.72975  -26.71556 -8.90170  1.000 11.67247 ? 1742 LEU A CA   1 
ATOM   4438 C  C    . LEU A 1 283 ? -3.86027  -27.61153 -9.77452  1.000 12.25149 ? 1742 LEU A C    1 
ATOM   4439 O  O    . LEU A 1 283 ? -3.13743  -27.12315 -10.64116 1.000 12.92262 ? 1742 LEU A O    1 
ATOM   4440 C  CB   . LEU A 1 283 ? -6.02623  -26.38129 -9.62915  1.000 12.11989 ? 1742 LEU A CB   1 
ATOM   4441 C  CG   . LEU A 1 283 ? -7.01129  -25.56610 -8.77458  1.000 12.32255 ? 1742 LEU A CG   1 
ATOM   4442 C  CD1  . LEU A 1 283 ? -8.10955  -24.91776 -9.61413  1.000 12.38572 ? 1742 LEU A CD1  1 
ATOM   4443 C  CD2  . LEU A 1 283 ? -7.64937  -26.40683 -7.68041  1.000 12.82787 ? 1742 LEU A CD2  1 
ATOM   4444 H  H    . LEU A 1 283 ? -4.08496  -24.86150 -9.15156  1.000 13.34653 ? 1742 LEU A H    1 
ATOM   4445 H  HA   . LEU A 1 283 ? -4.96137  -27.19789 -8.09262  1.000 14.00976 ? 1742 LEU A HA   1 
ATOM   4446 H  HB2  . LEU A 1 283 ? -5.81583  -25.86101 -10.42031 1.000 14.54667 ? 1742 LEU A HB2  1 
ATOM   4447 H  HB3  . LEU A 1 283 ? -6.46474  -27.20844 -9.88297  1.000 14.54667 ? 1742 LEU A HB3  1 
ATOM   4448 H  HG   . LEU A 1 283 ? -6.48937  -24.86180 -8.35929  1.000 14.78986 ? 1742 LEU A HG   1 
ATOM   4449 H  HD11 . LEU A 1 283 ? -8.70209  -24.42021 -9.02912  1.000 14.86566 ? 1742 LEU A HD11 1 
ATOM   4450 H  HD12 . LEU A 1 283 ? -7.70196  -24.31883 -10.25915 1.000 14.86566 ? 1742 LEU A HD12 1 
ATOM   4451 H  HD13 . LEU A 1 283 ? -8.60606  -25.61197 -10.07506 1.000 14.86566 ? 1742 LEU A HD13 1 
ATOM   4452 H  HD21 . LEU A 1 283 ? -8.30085  -25.86661 -7.20645  1.000 15.39624 ? 1742 LEU A HD21 1 
ATOM   4453 H  HD22 . LEU A 1 283 ? -8.08617  -27.17270 -8.08483  1.000 15.39624 ? 1742 LEU A HD22 1 
ATOM   4454 H  HD23 . LEU A 1 283 ? -6.95874  -26.70512 -7.06808  1.000 15.39624 ? 1742 LEU A HD23 1 
ATOM   4455 N  N    . PRO A 1 284 ? -3.90387  -28.91616 -9.54462  1.000 11.92250 ? 1743 PRO A N    1 
ATOM   4456 C  CA   . PRO A 1 284 ? -2.96758  -29.81633 -10.19747 1.000 11.78038 ? 1743 PRO A CA   1 
ATOM   4457 C  C    . PRO A 1 284 ? -3.39971  -30.14329 -11.60938 1.000 11.51193 ? 1743 PRO A C    1 
ATOM   4458 O  O    . PRO A 1 284 ? -4.58168  -30.01186 -11.96814 1.000 12.11200 ? 1743 PRO A O    1 
ATOM   4459 C  CB   . PRO A 1 284 ? -3.02593  -31.06579 -9.31427  1.000 11.95145 ? 1743 PRO A CB   1 
ATOM   4460 C  CG   . PRO A 1 284 ? -4.45250  -31.09317 -8.84668  1.000 12.30939 ? 1743 PRO A CG   1 
ATOM   4461 C  CD   . PRO A 1 284 ? -4.80018  -29.63288 -8.62082  1.000 12.22517 ? 1743 PRO A CD   1 
ATOM   4462 H  HA   . PRO A 1 284 ? -2.07472  -29.43735 -10.20576 1.000 14.13925 ? 1743 PRO A HA   1 
ATOM   4463 H  HB2  . PRO A 1 284 ? -2.80930  -31.85585 -9.83367  1.000 14.34454 ? 1743 PRO A HB2  1 
ATOM   4464 H  HB3  . PRO A 1 284 ? -2.41146  -30.98021 -8.56861  1.000 14.34454 ? 1743 PRO A HB3  1 
ATOM   4465 H  HG2  . PRO A 1 284 ? -5.01961  -31.48586 -9.52865  1.000 14.77407 ? 1743 PRO A HG2  1 
ATOM   4466 H  HG3  . PRO A 1 284 ? -4.52395  -31.60070 -8.02315  1.000 14.77407 ? 1743 PRO A HG3  1 
ATOM   4467 H  HD2  . PRO A 1 284 ? -5.72926  -29.46236 -8.84133  1.000 14.67300 ? 1743 PRO A HD2  1 
ATOM   4468 H  HD3  . PRO A 1 284 ? -4.62460  -29.37555 -7.70220  1.000 14.67300 ? 1743 PRO A HD3  1 
ATOM   4469 N  N    . PRO A 1 285 ? -2.47686  -30.59969 -12.43867 1.000 11.91987 ? 1744 PRO A N    1 
ATOM   4470 C  CA   . PRO A 1 285 ? -2.84632  -31.15820 -13.73526 1.000 11.93303 ? 1744 PRO A CA   1 
ATOM   4471 C  C    . PRO A 1 285 ? -3.73723  -32.37151 -13.58019 1.000 11.85144 ? 1744 PRO A C    1 
ATOM   4472 O  O    . PRO A 1 285 ? -3.71503  -33.06082 -12.55930 1.000 13.53585 ? 1744 PRO A O    1 
ATOM   4473 C  CB   . PRO A 1 285 ? -1.50739  -31.54371 -14.38166 1.000 12.82261 ? 1744 PRO A CB   1 
ATOM   4474 C  CG   . PRO A 1 285 ? -0.46535  -30.99402 -13.46188 1.000 13.76219 ? 1744 PRO A CG   1 
ATOM   4475 C  CD   . PRO A 1 285 ? -1.05679  -30.76137 -12.13923 1.000 12.30676 ? 1744 PRO A CD   1 
ATOM   4476 H  HA   . PRO A 1 285 ? -3.28465  -30.48365 -14.27724 1.000 14.32243 ? 1744 PRO A HA   1 
ATOM   4477 H  HB2  . PRO A 1 285 ? -1.43808  -32.50893 -14.44826 1.000 15.38993 ? 1744 PRO A HB2  1 
ATOM   4478 H  HB3  . PRO A 1 285 ? -1.43861  -31.14455 -15.26305 1.000 15.38993 ? 1744 PRO A HB3  1 
ATOM   4479 H  HG2  . PRO A 1 285 ? 0.25920   -31.63511 -13.39171 1.000 16.51743 ? 1744 PRO A HG2  1 
ATOM   4480 H  HG3  . PRO A 1 285 ? -0.13489  -30.15860 -13.82764 1.000 16.51743 ? 1744 PRO A HG3  1 
ATOM   4481 H  HD2  . PRO A 1 285 ? -0.91027  -31.52214 -11.55557 1.000 14.77091 ? 1744 PRO A HD2  1 
ATOM   4482 H  HD3  . PRO A 1 285 ? -0.69449  -29.95787 -11.73423 1.000 14.77091 ? 1744 PRO A HD3  1 
ATOM   4483 N  N    . GLN A 1 286 ? -4.48936  -32.65235 -14.63093 1.000 12.00409 ? 1745 GLN A N    1 
ATOM   4484 C  CA   . GLN A 1 286 ? -5.26436  -33.87858 -14.74109 1.000 12.08042 ? 1745 GLN A CA   1 
ATOM   4485 C  C    . GLN A 1 286 ? -4.61769  -34.70019 -15.84888 1.000 12.82261 ? 1745 GLN A C    1 
ATOM   4486 O  O    . GLN A 1 286 ? -4.61363  -34.28496 -17.01158 1.000 13.11738 ? 1745 GLN A O    1 
ATOM   4487 C  CB   . GLN A 1 286 ? -6.71189  -33.52882 -15.07762 1.000 11.80407 ? 1745 GLN A CB   1 
ATOM   4488 C  CG   . GLN A 1 286 ? -7.41559  -32.80917 -13.94470 1.000 11.71195 ? 1745 GLN A CG   1 
ATOM   4489 C  CD   . GLN A 1 286 ? -8.78384  -32.31268 -14.33491 1.000 11.61194 ? 1745 GLN A CD   1 
ATOM   4490 O  OE1  . GLN A 1 286 ? -8.92747  -31.42355 -15.15454 1.000 12.05146 ? 1745 GLN A OE1  1 
ATOM   4491 N  NE2  . GLN A 1 286 ? -9.80505  -32.95821 -13.80783 1.000 11.38296 ? 1745 GLN A NE2  1 
ATOM   4492 H  H    . GLN A 1 286 ? -4.56983  -32.13412 -15.31252 1.000 14.40771 ? 1745 GLN A H    1 
ATOM   4493 H  HA   . GLN A 1 286 ? -5.25897  -34.39609 -13.92069 1.000 14.49930 ? 1745 GLN A HA   1 
ATOM   4494 H  HB2  . GLN A 1 286 ? -6.72467  -32.95004 -15.85592 1.000 14.16768 ? 1745 GLN A HB2  1 
ATOM   4495 H  HB3  . GLN A 1 286 ? -7.19964  -34.34628 -15.26404 1.000 14.16768 ? 1745 GLN A HB3  1 
ATOM   4496 H  HG2  . GLN A 1 286 ? -7.51900  -33.41934 -13.19777 1.000 14.05714 ? 1745 GLN A HG2  1 
ATOM   4497 H  HG3  . GLN A 1 286 ? -6.88331  -32.04384 -13.67665 1.000 14.05714 ? 1745 GLN A HG3  1 
ATOM   4498 H  HE21 . GLN A 1 286 ? -9.66732  -33.61983 -13.27596 1.000 13.66235 ? 1745 GLN A HE21 1 
ATOM   4499 H  HE22 . GLN A 1 286 ? -10.60907 -32.71776 -13.99581 1.000 13.66235 ? 1745 GLN A HE22 1 
ATOM   4500 N  N    . GLU A 1 287 ? -4.06966  -35.86427 -15.48888 1.000 13.45690 ? 1746 GLU A N    1 
ATOM   4501 C  CA   . GLU A 1 287 ? -3.41804  -36.71331 -16.46974 1.000 15.23343 ? 1746 GLU A CA   1 
ATOM   4502 C  C    . GLU A 1 287 ? -4.43171  -37.19795 -17.50216 1.000 13.72535 ? 1746 GLU A C    1 
ATOM   4503 O  O    . GLU A 1 287 ? -5.59747  -37.41722 -17.19068 1.000 12.91736 ? 1746 GLU A O    1 
ATOM   4504 C  CB   . GLU A 1 287 ? -2.82087  -37.93804 -15.76644 1.000 19.43655 ? 1746 GLU A CB   1 
ATOM   4505 H  H    . GLU A 1 287 ? -4.06500  -36.17720 -14.68785 1.000 16.15107 ? 1746 GLU A H    1 
ATOM   4506 H  HA   . GLU A 1 287 ? -2.71572  -36.21627 -16.91760 1.000 18.28291 ? 1746 GLU A HA   1 
ATOM   4507 N  N    . ASP A 1 288 ? -3.97123  -37.35456 -18.73742 1.000 13.93327 ? 1747 ASP A N    1 
ATOM   4508 C  CA   A ASP A 1 288 ? -4.75599  -37.95665 -19.81384 0.538 14.17014 ? 1747 ASP A CA   1 
ATOM   4509 C  CA   B ASP A 1 288 ? -4.75840  -37.96762 -19.80136 0.462 14.97813 ? 1747 ASP A CA   1 
ATOM   4510 C  C    . ASP A 1 288 ? -6.16223  -37.37294 -19.88050 1.000 14.24910 ? 1747 ASP A C    1 
ATOM   4511 O  O    . ASP A 1 288 ? -7.16513  -38.09436 -19.87311 1.000 14.68336 ? 1747 ASP A O    1 
ATOM   4512 C  CB   A ASP A 1 288 ? -4.81389  -39.47420 -19.67993 0.538 14.45438 ? 1747 ASP A CB   1 
ATOM   4513 C  CB   B ASP A 1 288 ? -4.84459  -39.49559 -19.66682 0.462 16.74676 ? 1747 ASP A CB   1 
ATOM   4514 C  CG   A ASP A 1 288 ? -5.05091  -40.16570 -21.00770 0.538 15.02551 ? 1747 ASP A CG   1 
ATOM   4515 C  CG   B ASP A 1 288 ? -3.50127  -40.15682 -19.45424 0.462 18.23115 ? 1747 ASP A CG   1 
ATOM   4516 O  OD1  A ASP A 1 288 ? -5.05181  -39.49050 -22.06354 0.538 16.38356 ? 1747 ASP A OD1  1 
ATOM   4517 O  OD1  B ASP A 1 288 ? -2.73976  -40.19140 -20.43418 0.462 18.54698 ? 1747 ASP A OD1  1 
ATOM   4518 O  OD2  A ASP A 1 288 ? -5.24193  -41.39656 -20.99396 0.538 15.18079 ? 1747 ASP A OD2  1 
ATOM   4519 O  OD2  B ASP A 1 288 ? -3.25816  -40.73645 -18.36874 0.462 18.83912 ? 1747 ASP A OD2  1 
ATOM   4520 H  H    A ASP A 1 288 ? -3.18417  -37.11364 -18.98660 0.538 16.72272 ? 1747 ASP A H    1 
ATOM   4521 H  H    B ASP A 1 288 ? -3.18720  -37.10813 -18.99073 0.462 16.72272 ? 1747 ASP A H    1 
ATOM   4522 H  HA   A ASP A 1 288 ? -4.31006  -37.74305 -20.64836 0.538 17.00697 ? 1747 ASP A HA   1 
ATOM   4523 H  HA   B ASP A 1 288 ? -4.29406  -37.76853 -20.62941 0.462 17.97655 ? 1747 ASP A HA   1 
ATOM   4524 H  HB2  A ASP A 1 288 ? -3.97115  -39.79310 -19.32078 0.538 17.34806 ? 1747 ASP A HB2  1 
ATOM   4525 H  HB2  B ASP A 1 288 ? -5.40612  -39.71221 -18.90612 0.462 20.09891 ? 1747 ASP A HB2  1 
ATOM   4526 H  HB3  A ASP A 1 288 ? -5.54030  -39.71223 -19.08280 0.538 17.34806 ? 1747 ASP A HB3  1 
ATOM   4527 H  HB3  B ASP A 1 288 ? -5.23032  -39.86059 -20.47854 0.462 20.09891 ? 1747 ASP A HB3  1 
ATOM   4528 N  N    . THR A 1 289 ? -6.22529  -36.04866 -19.96191 1.000 13.46216 ? 1748 THR A N    1 
ATOM   4529 C  CA   . THR A 1 289 ? -7.47721  -35.29718 -19.90592 1.000 13.35162 ? 1748 THR A CA   1 
ATOM   4530 C  C    . THR A 1 289 ? -7.45869  -34.24492 -20.99853 1.000 13.28319 ? 1748 THR A C    1 
ATOM   4531 O  O    . THR A 1 289 ? -6.52060  -33.43135 -21.08367 1.000 13.82010 ? 1748 THR A O    1 
ATOM   4532 C  CB   . THR A 1 289 ? -7.62906  -34.65535 -18.52554 1.000 12.89104 ? 1748 THR A CB   1 
ATOM   4533 O  OG1  . THR A 1 289 ? -7.71351  -35.68150 -17.52527 1.000 12.76471 ? 1748 THR A OG1  1 
ATOM   4534 C  CG2  . THR A 1 289 ? -8.87431  -33.76749 -18.44712 1.000 12.67786 ? 1748 THR A CG2  1 
ATOM   4535 H  H    . THR A 1 289 ? -5.53406  -35.54517 -20.05297 1.000 16.15739 ? 1748 THR A H    1 
ATOM   4536 H  HA   . THR A 1 289 ? -8.24076  -35.87351 -20.06634 1.000 16.02474 ? 1748 THR A HA   1 
ATOM   4537 H  HB   . THR A 1 289 ? -6.85711  -34.09253 -18.35754 1.000 15.47204 ? 1748 THR A HB   1 
ATOM   4538 H  HG1  . THR A 1 289 ? -7.01641  -36.15006 -17.53479 1.000 15.32045 ? 1748 THR A HG1  1 
ATOM   4539 H  HG21 . THR A 1 289 ? -9.04392  -33.51450 -17.52618 1.000 15.21622 ? 1748 THR A HG21 1 
ATOM   4540 H  HG22 . THR A 1 289 ? -8.74298  -32.96444 -18.97510 1.000 15.21622 ? 1748 THR A HG22 1 
ATOM   4541 H  HG23 . THR A 1 289 ? -9.64536  -34.24648 -18.78910 1.000 15.21622 ? 1748 THR A HG23 1 
ATOM   4542 N  N    . TYR A 1 290 ? -8.51727  -34.22382 -21.80315 1.000 13.16739 ? 1749 TYR A N    1 
ATOM   4543 C  CA   . TYR A 1 290 ? -8.59792  -33.25117 -22.87837 1.000 13.30162 ? 1749 TYR A CA   1 
ATOM   4544 C  C    . TYR A 1 290 ? -10.02782 -33.15455 -23.38870 1.000 12.64891 ? 1749 TYR A C    1 
ATOM   4545 O  O    . TYR A 1 290 ? -10.88167 -34.00349 -23.09468 1.000 13.41215 ? 1749 TYR A O    1 
ATOM   4546 C  CB   . TYR A 1 290 ? -7.63972  -33.57564 -24.01588 1.000 14.98076 ? 1749 TYR A CB   1 
ATOM   4547 C  CG   . TYR A 1 290 ? -7.76580  -34.96486 -24.57069 1.000 17.04154 ? 1749 TYR A CG   1 
ATOM   4548 C  CD1  . TYR A 1 290 ? -7.12043  -36.03131 -23.96927 1.000 18.64699 ? 1749 TYR A CD1  1 
ATOM   4549 C  CD2  . TYR A 1 290 ? -8.54063  -35.21938 -25.69520 1.000 18.44434 ? 1749 TYR A CD2  1 
ATOM   4550 C  CE1  . TYR A 1 290 ? -7.22407  -37.30483 -24.47510 1.000 20.15770 ? 1749 TYR A CE1  1 
ATOM   4551 C  CE2  . TYR A 1 290 ? -8.63902  -36.51806 -26.22518 1.000 20.26824 ? 1749 TYR A CE2  1 
ATOM   4552 C  CZ   . TYR A 1 290 ? -7.98223  -37.54446 -25.59856 1.000 20.97885 ? 1749 TYR A CZ   1 
ATOM   4553 O  OH   . TYR A 1 290 ? -8.07026  -38.82192 -26.07941 1.000 23.32123 ? 1749 TYR A OH   1 
ATOM   4554 H  H    . TYR A 1 290 ? -9.19021  -34.75613 -21.74481 1.000 15.80366 ? 1749 TYR A H    1 
ATOM   4555 H  HA   . TYR A 1 290 ? -8.35825  -32.38660 -22.50962 1.000 15.96474 ? 1749 TYR A HA   1 
ATOM   4556 H  HB2  . TYR A 1 290 ? -7.80455  -32.95540 -24.74322 1.000 17.97971 ? 1749 TYR A HB2  1 
ATOM   4557 H  HB3  . TYR A 1 290 ? -6.73133  -33.47279 -23.69159 1.000 17.97971 ? 1749 TYR A HB3  1 
ATOM   4558 H  HD1  . TYR A 1 290 ? -6.60679  -35.88322 -23.20825 1.000 22.37919 ? 1749 TYR A HD1  1 
ATOM   4559 H  HD2  . TYR A 1 290 ? -9.00048  -34.52143 -26.10300 1.000 22.13600 ? 1749 TYR A HD2  1 
ATOM   4560 H  HE1  . TYR A 1 290 ? -6.78044  -38.00712 -24.05691 1.000 24.19204 ? 1749 TYR A HE1  1 
ATOM   4561 H  HE2  . TYR A 1 290 ? -9.14285  -36.67814 -26.99032 1.000 24.32468 ? 1749 TYR A HE2  1 
ATOM   4562 H  HH   . TYR A 1 290 ? -8.55631  -38.83824 -26.76431 1.000 27.98828 ? 1749 TYR A HH   1 
ATOM   4563 N  N    . VAL A 1 291 ? -10.25958 -32.10212 -24.17470 1.000 12.41204 ? 1750 VAL A N    1 
ATOM   4564 C  CA   . VAL A 1 291 ? -11.57529 -31.73696 -24.68381 1.000 12.81472 ? 1750 VAL A CA   1 
ATOM   4565 C  C    . VAL A 1 291 ? -11.45255 -31.52012 -26.18337 1.000 13.93064 ? 1750 VAL A C    1 
ATOM   4566 O  O    . VAL A 1 291 ? -10.58432 -30.77088 -26.63608 1.000 15.18342 ? 1750 VAL A O    1 
ATOM   4567 C  CB   . VAL A 1 291 ? -12.06811 -30.44638 -24.00214 1.000 13.78852 ? 1750 VAL A CB   1 
ATOM   4568 C  CG1  . VAL A 1 291 ? -13.41278 -30.01498 -24.56505 1.000 15.02287 ? 1750 VAL A CG1  1 
ATOM   4569 C  CG2  . VAL A 1 291 ? -12.12853 -30.63340 -22.50729 1.000 13.85694 ? 1750 VAL A CG2  1 
ATOM   4570 H  H    . VAL A 1 291 ? -9.64177  -31.56384 -24.43578 1.000 14.89724 ? 1750 VAL A H    1 
ATOM   4571 H  HA   . VAL A 1 291 ? -12.21169 -32.45206 -24.52723 1.000 15.38046 ? 1750 VAL A HA   1 
ATOM   4572 H  HB   . VAL A 1 291 ? -11.43842 -29.73175 -24.18573 1.000 16.54902 ? 1750 VAL A HB   1 
ATOM   4573 H  HG11 . VAL A 1 291 ? -13.79099 -29.33116 -23.99038 1.000 18.03024 ? 1750 VAL A HG11 1 
ATOM   4574 H  HG12 . VAL A 1 291 ? -13.28216 -29.66098 -25.45865 1.000 18.03024 ? 1750 VAL A HG12 1 
ATOM   4575 H  HG13 . VAL A 1 291 ? -14.00317 -30.78395 -24.59692 1.000 18.03024 ? 1750 VAL A HG13 1 
ATOM   4576 H  HG21 . VAL A 1 291 ? -12.49332 -29.83063 -22.10308 1.000 16.63113 ? 1750 VAL A HG21 1 
ATOM   4577 H  HG22 . VAL A 1 291 ? -12.69784 -31.39274 -22.30679 1.000 16.63113 ? 1750 VAL A HG22 1 
ATOM   4578 H  HG23 . VAL A 1 291 ? -11.23241 -30.79436 -22.17269 1.000 16.63113 ? 1750 VAL A HG23 1 
ATOM   4579 N  N    . GLU A 1 292 ? -12.30129 -32.17742 -26.96077 1.000 14.07803 ? 1751 GLU A N    1 
ATOM   4580 C  CA   . GLU A 1 292 ? -12.30940 -32.00813 -28.40771 1.000 14.94655 ? 1751 GLU A CA   1 
ATOM   4581 C  C    . GLU A 1 292 ? -13.51234 -31.16340 -28.79145 1.000 14.11224 ? 1751 GLU A C    1 
ATOM   4582 O  O    . GLU A 1 292 ? -14.64312 -31.49920 -28.42405 1.000 14.26752 ? 1751 GLU A O    1 
ATOM   4583 C  CB   . GLU A 1 292 ? -12.31251 -33.35727 -29.12788 1.000 17.12576 ? 1751 GLU A CB   1 
ATOM   4584 C  CG   . GLU A 1 292 ? -11.10945 -34.21741 -28.74284 1.000 20.06822 ? 1751 GLU A CG   1 
ATOM   4585 C  CD   . GLU A 1 292 ? -11.12315 -35.60781 -29.36828 1.000 23.15016 ? 1751 GLU A CD   1 
ATOM   4586 O  OE1  . GLU A 1 292 ? -12.20780 -36.10462 -29.73279 1.000 24.44769 ? 1751 GLU A OE1  1 
ATOM   4587 O  OE2  . GLU A 1 292 ? -10.04152 -36.22614 -29.47828 1.000 24.93459 ? 1751 GLU A OE2  1 
ATOM   4588 H  H    . GLU A 1 292 ? -12.88914 -32.73380 -26.67012 1.000 16.89643 ? 1751 GLU A H    1 
ATOM   4589 H  HA   . GLU A 1 292 ? -11.50984 -31.53486 -28.68632 1.000 17.93866 ? 1751 GLU A HA   1 
ATOM   4590 H  HB2  . GLU A 1 292 ? -13.11926 -33.84170 -28.89255 1.000 20.55371 ? 1751 GLU A HB2  1 
ATOM   4591 H  HB3  . GLU A 1 292 ? -12.28342 -33.20673 -30.08569 1.000 20.55371 ? 1751 GLU A HB3  1 
ATOM   4592 H  HG2  . GLU A 1 292 ? -10.29965 -33.77003 -29.03435 1.000 24.08466 ? 1751 GLU A HG2  1 
ATOM   4593 H  HG3  . GLU A 1 292 ? -11.09947 -34.32680 -27.77908 1.000 24.08466 ? 1751 GLU A HG3  1 
ATOM   4594 N  N    . VAL A 1 293 ? -13.26147 -30.04712 -29.49007 1.000 14.43596 ? 1752 VAL A N    1 
ATOM   4595 C  CA   . VAL A 1 293 ? -14.31603 -29.12891 -29.91319 1.000 14.56756 ? 1752 VAL A CA   1 
ATOM   4596 C  C    . VAL A 1 293 ? -14.34573 -29.02130 -31.43463 1.000 14.72021 ? 1752 VAL A C    1 
ATOM   4597 O  O    . VAL A 1 293 ? -13.32725 -29.14580 -32.12515 1.000 14.94128 ? 1752 VAL A O    1 
ATOM   4598 C  CB   . VAL A 1 293 ? -14.16060 -27.72752 -29.26742 1.000 15.33607 ? 1752 VAL A CB   1 
ATOM   4599 C  CG1  . VAL A 1 293 ? -14.18262 -27.83116 -27.77504 1.000 15.81244 ? 1752 VAL A CG1  1 
ATOM   4600 C  CG2  . VAL A 1 293 ? -12.89452 -27.02673 -29.75909 1.000 16.59411 ? 1752 VAL A CG2  1 
ATOM   4601 H  H    . VAL A 1 293 ? -12.47393 -29.80070 -29.73228 1.000 17.32595 ? 1752 VAL A H    1 
ATOM   4602 H  HA   . VAL A 1 293 ? -15.16662 -29.50427 -29.63660 1.000 17.48387 ? 1752 VAL A HA   1 
ATOM   4603 H  HB   . VAL A 1 293 ? -14.91281 -27.17818 -29.53815 1.000 18.40608 ? 1752 VAL A HB   1 
ATOM   4604 H  HG11 . VAL A 1 293 ? -14.13839 -26.93944 -27.39586 1.000 18.97773 ? 1752 VAL A HG11 1 
ATOM   4605 H  HG12 . VAL A 1 293 ? -15.00477 -28.26680 -27.50082 1.000 18.97773 ? 1752 VAL A HG12 1 
ATOM   4606 H  HG13 . VAL A 1 293 ? -13.41865 -28.35288 -27.48340 1.000 18.97773 ? 1752 VAL A HG13 1 
ATOM   4607 H  HG21 . VAL A 1 293 ? -12.74804 -26.22919 -29.22677 1.000 19.91573 ? 1752 VAL A HG21 1 
ATOM   4608 H  HG22 . VAL A 1 293 ? -12.14176 -27.63101 -29.66363 1.000 19.91573 ? 1752 VAL A HG22 1 
ATOM   4609 H  HG23 . VAL A 1 293 ? -13.00893 -26.78560 -30.69164 1.000 19.91573 ? 1752 VAL A HG23 1 
ATOM   4610 N  N    . ASP A 1 294 ? -15.54848 -28.79186 -31.95571 1.000 14.85180 ? 1753 ASP A N    1 
ATOM   4611 C  CA   . ASP A 1 294 ? -15.81399 -28.55762 -33.36875 1.000 16.35198 ? 1753 ASP A CA   1 
ATOM   4612 C  C    . ASP A 1 294 ? -16.10373 -27.06736 -33.46510 1.000 16.63359 ? 1753 ASP A C    1 
ATOM   4613 O  O    . ASP A 1 294 ? -17.12001 -26.59135 -32.94207 1.000 16.53621 ? 1753 ASP A O    1 
ATOM   4614 C  CB   . ASP A 1 294 ? -17.04401 -29.35764 -33.78043 1.000 18.78385 ? 1753 ASP A CB   1 
ATOM   4615 C  CG   . ASP A 1 294 ? -17.45252 -29.13133 -35.20653 1.000 21.50786 ? 1753 ASP A CG   1 
ATOM   4616 O  OD1  . ASP A 1 294 ? -18.25626 -29.94368 -35.68019 1.000 23.42914 ? 1753 ASP A OD1  1 
ATOM   4617 O  OD2  . ASP A 1 294 ? -16.94362 -28.22043 -35.88055 1.000 22.48693 ? 1753 ASP A OD2  1 
ATOM   4618 H  H    . ASP A 1 294 ? -16.26562 -28.76604 -31.48174 1.000 17.82496 ? 1753 ASP A H    1 
ATOM   4619 H  HA   . ASP A 1 294 ? -15.06675 -28.80414 -33.93600 1.000 19.62518 ? 1753 ASP A HA   1 
ATOM   4620 H  HB2  . ASP A 1 294 ? -16.85414 -30.30268 -33.67209 1.000 22.54342 ? 1753 ASP A HB2  1 
ATOM   4621 H  HB3  . ASP A 1 294 ? -17.78860 -29.10176 -33.21384 1.000 22.54342 ? 1753 ASP A HB3  1 
ATOM   4622 N  N    . LEU A 1 295 ? -15.20270 -26.33172 -34.09784 1.000 17.80742 ? 1754 LEU A N    1 
ATOM   4623 C  CA   . LEU A 1 295 ? -15.30615 -24.88454 -34.14057 1.000 19.87346 ? 1754 LEU A CA   1 
ATOM   4624 C  C    . LEU A 1 295 ? -16.19707 -24.39119 -35.26198 1.000 21.56840 ? 1754 LEU A C    1 
ATOM   4625 O  O    . LEU A 1 295 ? -16.42160 -23.18079 -35.36360 1.000 22.39481 ? 1754 LEU A O    1 
ATOM   4626 C  CB   . LEU A 1 295 ? -13.92398 -24.24027 -34.29546 1.000 21.06834 ? 1754 LEU A CB   1 
ATOM   4627 C  CG   . LEU A 1 295 ? -12.92421 -24.46994 -33.15807 1.000 22.38428 ? 1754 LEU A CG   1 
ATOM   4628 C  CD1  . LEU A 1 295 ? -11.63011 -23.69800 -33.45789 1.000 23.53705 ? 1754 LEU A CD1  1 
ATOM   4629 C  CD2  . LEU A 1 295 ? -13.51353 -24.07663 -31.82278 1.000 23.13174 ? 1754 LEU A CD2  1 
ATOM   4630 H  H    . LEU A 1 295 ? -14.51940 -26.65025 -34.51166 1.000 21.37170 ? 1754 LEU A H    1 
ATOM   4631 H  HA   . LEU A 1 295 ? -15.67883 -24.59165 -33.29427 1.000 23.85095 ? 1754 LEU A HA   1 
ATOM   4632 H  HB2  . LEU A 1 295 ? -13.51924 -24.59088 -35.10426 1.000 25.28480 ? 1754 LEU A HB2  1 
ATOM   4633 H  HB3  . LEU A 1 295 ? -14.04787 -23.28152 -34.37519 1.000 25.28480 ? 1754 LEU A HB3  1 
ATOM   4634 H  HG   . LEU A 1 295 ? -12.71048 -25.41394 -33.09409 1.000 26.86394 ? 1754 LEU A HG   1 
ATOM   4635 H  HD11 . LEU A 1 295 ? -11.00308 -23.83841 -32.73125 1.000 28.24726 ? 1754 LEU A HD11 1 
ATOM   4636 H  HD12 . LEU A 1 295 ? -11.25217 -24.02583 -34.28892 1.000 28.24726 ? 1754 LEU A HD12 1 
ATOM   4637 H  HD13 . LEU A 1 295 ? -11.83708 -22.75377 -33.53841 1.000 28.24726 ? 1754 LEU A HD13 1 
ATOM   4638 H  HD21 . LEU A 1 295 ? -12.81158 -24.08376 -31.15337 1.000 27.76088 ? 1754 LEU A HD21 1 
ATOM   4639 H  HD22 . LEU A 1 295 ? -13.89289 -23.18680 -31.89482 1.000 27.76088 ? 1754 LEU A HD22 1 
ATOM   4640 H  HD23 . LEU A 1 295 ? -14.20549 -24.71282 -31.58328 1.000 27.76088 ? 1754 LEU A HD23 1 
ATOM   4641 N  N    . GLU A 1 296 ? -16.70105 -25.28074 -36.11144 1.000 22.64221 ? 1755 GLU A N    1 
ATOM   4642 C  CA   . GLU A 1 296 ? -17.46489 -24.84869 -37.26959 1.000 24.91353 ? 1755 GLU A CA   1 
ATOM   4643 C  C    . GLU A 1 296 ? -18.96623 -24.96984 -37.06695 1.000 24.26346 ? 1755 GLU A C    1 
ATOM   4644 O  O    . GLU A 1 296 ? -19.72709 -24.37274 -37.83229 1.000 24.76351 ? 1755 GLU A O    1 
ATOM   4645 C  CB   . GLU A 1 296 ? -17.04134 -25.63371 -38.51746 1.000 28.21130 ? 1755 GLU A CB   1 
ATOM   4646 C  CG   . GLU A 1 296 ? -15.64378 -25.25569 -39.05761 1.000 31.36431 ? 1755 GLU A CG   1 
ATOM   4647 C  CD   . GLU A 1 296 ? -15.48565 -23.75930 -39.37536 1.000 33.88040 ? 1755 GLU A CD   1 
ATOM   4648 O  OE1  . GLU A 1 296 ? -16.37329 -23.18212 -40.05020 1.000 34.86736 ? 1755 GLU A OE1  1 
ATOM   4649 O  OE2  . GLU A 1 296 ? -14.47096 -23.15317 -38.95605 1.000 34.77261 ? 1755 GLU A OE2  1 
ATOM   4650 H  H    . GLU A 1 296 ? -16.61319 -26.13295 -36.03650 1.000 27.17345 ? 1755 GLU A H    1 
ATOM   4651 H  HA   . GLU A 1 296 ? -17.26738 -23.91467 -37.44137 1.000 29.89904 ? 1755 GLU A HA   1 
ATOM   4652 H  HB2  . GLU A 1 296 ? -17.02713 -26.57881 -38.29954 1.000 33.85635 ? 1755 GLU A HB2  1 
ATOM   4653 H  HB3  . GLU A 1 296 ? -17.68522 -25.46562 -39.22320 1.000 33.85635 ? 1755 GLU A HB3  1 
ATOM   4654 H  HG2  . GLU A 1 296 ? -14.97823 -25.48833 -38.39141 1.000 37.63996 ? 1755 GLU A HG2  1 
ATOM   4655 H  HG3  . GLU A 1 296 ? -15.48110 -25.75043 -39.87594 1.000 37.63996 ? 1755 GLU A HG3  1 
ATOM   4656 N  N    . HIS A 1 297 ? -19.40324 -25.68655 -36.04035 1.000 23.54232 ? 1756 HIS A N    1 
ATOM   4657 C  CA   . HIS A 1 297 ? -20.81308 -26.01445 -35.88692 1.000 23.37651 ? 1756 HIS A CA   1 
ATOM   4658 C  C    . HIS A 1 297 ? -21.59524 -24.81286 -35.36588 1.000 21.57366 ? 1756 HIS A C    1 
ATOM   4659 O  O    . HIS A 1 297 ? -21.37641 -24.36239 -34.23804 1.000 20.46826 ? 1756 HIS A O    1 
ATOM   4660 C  CB   . HIS A 1 297 ? -20.97654 -27.19138 -34.92872 1.000 24.71614 ? 1756 HIS A CB   1 
ATOM   4661 C  CG   . HIS A 1 297 ? -22.38244 -27.68450 -34.84149 1.000 25.97682 ? 1756 HIS A CG   1 
ATOM   4662 N  ND1  . HIS A 1 297 ? -23.13711 -27.59438 -33.69161 1.000 26.86640 ? 1756 HIS A ND1  1 
ATOM   4663 C  CD2  . HIS A 1 297 ? -23.18556 -28.24086 -35.77818 1.000 26.20843 ? 1756 HIS A CD2  1 
ATOM   4664 C  CE1  . HIS A 1 297 ? -24.34230 -28.08779 -33.92095 1.000 26.51899 ? 1756 HIS A CE1  1 
ATOM   4665 N  NE2  . HIS A 1 297 ? -24.39938 -28.47993 -35.18068 1.000 26.46635 ? 1756 HIS A NE2  1 
ATOM   4666 H  H    . HIS A 1 297 ? -18.90027 -25.99656 -35.41544 1.000 28.25358 ? 1756 HIS A H    1 
ATOM   4667 H  HA   . HIS A 1 297 ? -21.16872 -26.25273 -36.75735 1.000 28.05461 ? 1756 HIS A HA   1 
ATOM   4668 H  HB2  . HIS A 1 297 ? -20.42085 -27.92528 -35.23448 1.000 29.66217 ? 1756 HIS A HB2  1 
ATOM   4669 H  HB3  . HIS A 1 297 ? -20.70134 -26.91445 -34.04076 1.000 29.66217 ? 1756 HIS A HB3  1 
ATOM   4670 H  HD1  . HIS A 1 297 ? -22.86677 -27.26861 -32.94302 1.000 32.24247 ? 1756 HIS A HD1  1 
ATOM   4671 H  HD2  . HIS A 1 297 ? -22.95837 -28.42649 -36.66069 1.000 31.45291 ? 1756 HIS A HD2  1 
ATOM   4672 H  HE1  . HIS A 1 297 ? -25.03245 -28.14835 -33.30053 1.000 31.82558 ? 1756 HIS A HE1  1 
ATOM   4673 N  N    . GLU A 1 298 ? -22.52590 -24.31626 -36.17656 1.000 21.78684 ? 1757 GLU A N    1 
ATOM   4674 C  CA   . GLU A 1 298 ? -23.38623 -23.20918 -35.78525 1.000 22.20795 ? 1757 GLU A CA   1 
ATOM   4675 C  C    . GLU A 1 298 ? -24.69180 -23.74514 -35.20522 1.000 20.17612 ? 1757 GLU A C    1 
ATOM   4676 O  O    . GLU A 1 298 ? -25.32068 -24.63183 -35.78690 1.000 21.12624 ? 1757 GLU A O    1 
ATOM   4677 C  CB   . GLU A 1 298 ? -23.69069 -22.36745 -37.01940 1.000 25.40043 ? 1757 GLU A CB   1 
ATOM   4678 C  CG   . GLU A 1 298 ? -22.45478 -21.74908 -37.66404 1.000 28.87980 ? 1757 GLU A CG   1 
ATOM   4679 C  CD   . GLU A 1 298 ? -22.81030 -20.94732 -38.91167 1.000 32.61972 ? 1757 GLU A CD   1 
ATOM   4680 O  OE1  . GLU A 1 298 ? -23.39542 -21.53725 -39.84267 1.000 34.04620 ? 1757 GLU A OE1  1 
ATOM   4681 O  OE2  . GLU A 1 298 ? -22.53855 -19.73421 -38.95702 1.000 34.29097 ? 1757 GLU A OE2  1 
ATOM   4682 H  H    . GLU A 1 298 ? -22.67906 -24.60964 -36.97033 1.000 26.14701 ? 1757 GLU A H    1 
ATOM   4683 H  HA   . GLU A 1 298 ? -22.95098 -22.66782 -35.10820 1.000 26.65233 ? 1757 GLU A HA   1 
ATOM   4684 H  HB2  . GLU A 1 298 ? -24.11967 -22.93067 -37.68246 1.000 30.48332 ? 1757 GLU A HB2  1 
ATOM   4685 H  HB3  . GLU A 1 298 ? -24.28449 -21.64410 -36.76432 1.000 30.48332 ? 1757 GLU A HB3  1 
ATOM   4686 H  HG2  . GLU A 1 298 ? -22.02790 -21.15192 -37.02994 1.000 34.65856 ? 1757 GLU A HG2  1 
ATOM   4687 H  HG3  . GLU A 1 298 ? -21.84059 -22.45470 -37.92051 1.000 34.65856 ? 1757 GLU A HG3  1 
ATOM   4688 N  N    . TRP A 1 299 ? -25.10045 -23.19152 -34.06943 1.000 17.91270 ? 1758 TRP A N    1 
ATOM   4689 C  CA   . TRP A 1 299 ? -26.33458 -23.59303 -33.41504 1.000 16.80204 ? 1758 TRP A CA   1 
ATOM   4690 C  C    . TRP A 1 299 ? -26.87299 -22.41800 -32.61753 1.000 16.49674 ? 1758 TRP A C    1 
ATOM   4691 O  O    . TRP A 1 299 ? -26.17324 -21.43323 -32.38661 1.000 17.43632 ? 1758 TRP A O    1 
ATOM   4692 C  CB   . TRP A 1 299 ? -26.13494 -24.83081 -32.55198 1.000 16.46778 ? 1758 TRP A CB   1 
ATOM   4693 C  CG   . TRP A 1 299 ? -25.06335 -24.79043 -31.50589 1.000 15.76507 ? 1758 TRP A CG   1 
ATOM   4694 C  CD1  . TRP A 1 299 ? -23.71298 -24.81690 -31.70829 1.000 16.30987 ? 1758 TRP A CD1  1 
ATOM   4695 C  CD2  . TRP A 1 299 ? -25.25444 -24.78530 -30.09619 1.000 15.57820 ? 1758 TRP A CD2  1 
ATOM   4696 N  NE1  . TRP A 1 299 ? -23.05717 -24.82539 -30.50658 1.000 16.53358 ? 1758 TRP A NE1  1 
ATOM   4697 C  CE2  . TRP A 1 299 ? -23.98336 -24.81043 -29.49735 1.000 16.23091 ? 1758 TRP A CE2  1 
ATOM   4698 C  CE3  . TRP A 1 299 ? -26.38130 -24.77256 -29.27625 1.000 15.52820 ? 1758 TRP A CE3  1 
ATOM   4699 C  CZ2  . TRP A 1 299 ? -23.80282 -24.81213 -28.12120 1.000 16.42304 ? 1758 TRP A CZ2  1 
ATOM   4700 C  CZ3  . TRP A 1 299 ? -26.20674 -24.76270 -27.91510 1.000 16.42567 ? 1758 TRP A CZ3  1 
ATOM   4701 C  CH2  . TRP A 1 299 ? -24.92295 -24.79221 -27.34355 1.000 16.51516 ? 1758 TRP A CH2  1 
ATOM   4702 H  H    . TRP A 1 299 ? -24.67284 -22.57219 -33.65330 1.000 21.49803 ? 1758 TRP A H    1 
ATOM   4703 H  HA   . TRP A 1 299 ? -26.99839 -23.81505 -34.08657 1.000 20.16524 ? 1758 TRP A HA   1 
ATOM   4704 H  HB2  . TRP A 1 299 ? -26.96907 -25.00626 -32.08900 1.000 19.76414 ? 1758 TRP A HB2  1 
ATOM   4705 H  HB3  . TRP A 1 299 ? -25.92056 -25.57086 -33.14127 1.000 19.76414 ? 1758 TRP A HB3  1 
ATOM   4706 H  HD1  . TRP A 1 299 ? -23.29921 -24.82761 -32.54111 1.000 19.57464 ? 1758 TRP A HD1  1 
ATOM   4707 H  HE1  . TRP A 1 299 ? -22.20360 -24.83804 -30.40235 1.000 19.84309 ? 1758 TRP A HE1  1 
ATOM   4708 H  HE3  . TRP A 1 299 ? -27.23529 -24.77076 -29.64450 1.000 18.63663 ? 1758 TRP A HE3  1 
ATOM   4709 H  HZ2  . TRP A 1 299 ? -22.95255 -24.82627 -27.74472 1.000 19.71045 ? 1758 TRP A HZ2  1 
ATOM   4710 H  HZ3  . TRP A 1 299 ? -26.95243 -24.73598 -27.36000 1.000 19.71360 ? 1758 TRP A HZ3  1 
ATOM   4711 H  HH2  . TRP A 1 299 ? -24.83576 -24.79826 -26.41767 1.000 19.82099 ? 1758 TRP A HH2  1 
ATOM   4712 N  N    . THR A 1 300 ? -28.13185 -22.53397 -32.20921 1.000 16.56253 ? 1759 THR A N    1 
ATOM   4713 C  CA   . THR A 1 300 ? -28.81602 -21.51803 -31.42580 1.000 16.63886 ? 1759 THR A CA   1 
ATOM   4714 C  C    . THR A 1 300 ? -29.11146 -22.08052 -30.04671 1.000 16.00983 ? 1759 THR A C    1 
ATOM   4715 O  O    . THR A 1 300 ? -29.60446 -23.21067 -29.92266 1.000 16.53095 ? 1759 THR A O    1 
ATOM   4716 C  CB   . THR A 1 300 ? -30.11021 -21.10230 -32.12995 1.000 18.13904 ? 1759 THR A CB   1 
ATOM   4717 O  OG1  . THR A 1 300 ? -29.78978 -20.48458 -33.38244 1.000 19.21022 ? 1759 THR A OG1  1 
ATOM   4718 C  CG2  . THR A 1 300 ? -30.87784 -20.11704 -31.31509 1.000 18.76543 ? 1759 THR A CG2  1 
ATOM   4719 H  H    . THR A 1 300 ? -28.62543 -23.21698 -32.38089 1.000 19.87784 ? 1759 THR A H    1 
ATOM   4720 H  HA   . THR A 1 300 ? -28.25771 -20.73226 -31.31737 1.000 19.96943 ? 1759 THR A HA   1 
ATOM   4721 H  HB   . THR A 1 300 ? -30.65900 -21.89087 -32.26368 1.000 21.76964 ? 1759 THR A HB   1 
ATOM   4722 H  HG1  . THR A 1 300 ? -29.38685 -21.03073 -33.87738 1.000 23.05506 ? 1759 THR A HG1  1 
ATOM   4723 H  HG21 . THR A 1 300 ? -31.56959 -19.70590 -31.85671 1.000 22.52131 ? 1759 THR A HG21 1 
ATOM   4724 H  HG22 . THR A 1 300 ? -31.29256 -20.56261 -30.55986 1.000 22.52131 ? 1759 THR A HG22 1 
ATOM   4725 H  HG23 . THR A 1 300 ? -30.28368 -19.42506 -30.98489 1.000 22.52131 ? 1759 THR A HG23 1 
ATOM   4726 N  N    . ILE A 1 301 ? -28.77997 -21.31442 -29.01275 1.000 15.34133 ? 1760 ILE A N    1 
ATOM   4727 C  CA   A ILE A 1 301 ? -28.99183 -21.82579 -27.65826 0.717 15.03867 ? 1760 ILE A CA   1 
ATOM   4728 C  CA   B ILE A 1 301 ? -28.99119 -21.78603 -27.63657 0.283 15.33081 ? 1760 ILE A CA   1 
ATOM   4729 C  C    . ILE A 1 301 ? -30.48489 -22.00845 -27.40938 1.000 15.24132 ? 1760 ILE A C    1 
ATOM   4730 O  O    . ILE A 1 301 ? -31.28107 -21.07969 -27.64831 1.000 15.28870 ? 1760 ILE A O    1 
ATOM   4731 C  CB   A ILE A 1 301 ? -28.35700 -20.87394 -26.62424 0.717 14.19383 ? 1760 ILE A CB   1 
ATOM   4732 C  CB   B ILE A 1 301 ? -28.44740 -20.74629 -26.63537 0.283 15.22290 ? 1760 ILE A CB   1 
ATOM   4733 C  CG1  A ILE A 1 301 ? -26.84767 -20.90046 -26.84114 0.717 14.33595 ? 1760 ILE A CG1  1 
ATOM   4734 C  CG1  B ILE A 1 301 ? -26.97894 -20.42834 -26.91965 0.283 15.36502 ? 1760 ILE A CG1  1 
ATOM   4735 C  CG2  A ILE A 1 301 ? -28.70679 -21.28809 -25.21432 0.717 13.98854 ? 1760 ILE A CG2  1 
ATOM   4736 C  CG2  B ILE A 1 301 ? -28.64140 -21.23152 -25.20343 0.283 15.19132 ? 1760 ILE A CG2  1 
ATOM   4737 C  CD1  A ILE A 1 301 ? -26.10505 -19.97714 -25.94844 0.717 14.00170 ? 1760 ILE A CD1  1 
ATOM   4738 C  CD1  B ILE A 1 301 ? -26.06055 -21.61083 -26.80122 0.283 15.19921 ? 1760 ILE A CD1  1 
ATOM   4739 H  H    A ILE A 1 301 ? -28.44335 -20.52461 -29.06256 0.717 18.41240 ? 1760 ILE A H    1 
ATOM   4740 H  H    B ILE A 1 301 ? -28.43593 -20.52850 -29.07238 0.283 18.41240 ? 1760 ILE A H    1 
ATOM   4741 H  HA   A ILE A 1 301 ? -28.57046 -22.69501 -27.56990 0.717 18.04920 ? 1760 ILE A HA   1 
ATOM   4742 H  HA   B ILE A 1 301 ? -28.52630 -22.62725 -27.50568 0.283 18.39976 ? 1760 ILE A HA   1 
ATOM   4743 H  HB   A ILE A 1 301 ? -28.70080 -19.97517 -26.74644 0.717 17.03539 ? 1760 ILE A HB   1 
ATOM   4744 H  HB   B ILE A 1 301 ? -28.95175 -19.92535 -26.74762 0.283 18.27027 ? 1760 ILE A HB   1 
ATOM   4745 H  HG12 A ILE A 1 301 ? -26.52347 -21.79941 -26.67474 0.717 17.20594 ? 1760 ILE A HG12 1 
ATOM   4746 H  HG12 B ILE A 1 301 ? -26.90473 -20.08736 -27.82471 0.283 18.44082 ? 1760 ILE A HG12 1 
ATOM   4747 H  HG13 A ILE A 1 301 ? -26.65874 -20.64393 -27.75733 0.717 17.20594 ? 1760 ILE A HG13 1 
ATOM   4748 H  HG13 B ILE A 1 301 ? -26.67840 -19.75754 -26.28672 0.283 18.44082 ? 1760 ILE A HG13 1 
ATOM   4749 H  HG21 A ILE A 1 301 ? -28.20450 -20.74077 -24.59059 0.717 16.78904 ? 1760 ILE A HG21 1 
ATOM   4750 H  HG21 B ILE A 1 301 ? -28.07725 -20.70770 -24.61332 0.283 18.23238 ? 1760 ILE A HG21 1 
ATOM   4751 H  HG22 A ILE A 1 301 ? -29.65815 -21.16052 -25.07453 0.717 16.78904 ? 1760 ILE A HG22 1 
ATOM   4752 H  HG22 B ILE A 1 301 ? -29.57261 -21.12022 -24.95571 0.283 18.23238 ? 1760 ILE A HG22 1 
ATOM   4753 H  HG23 A ILE A 1 301 ? -28.47712 -22.22274 -25.09355 0.717 16.78904 ? 1760 ILE A HG23 1 
ATOM   4754 H  HG23 B ILE A 1 301 ? -28.39493 -22.16824 -25.15129 0.283 18.23238 ? 1760 ILE A HG23 1 
ATOM   4755 H  HD11 A ILE A 1 301 ? -25.20548 -19.86089 -26.29219 0.717 16.80484 ? 1760 ILE A HD11 1 
ATOM   4756 H  HD11 B ILE A 1 301 ? -25.15803 -21.29471 -26.63866 0.283 18.24185 ? 1760 ILE A HD11 1 
ATOM   4757 H  HD12 A ILE A 1 301 ? -26.56357 -19.12265 -25.92599 0.717 16.80484 ? 1760 ILE A HD12 1 
ATOM   4758 H  HD12 B ILE A 1 301 ? -26.35457 -22.16630 -26.06237 0.283 18.24185 ? 1760 ILE A HD12 1 
ATOM   4759 H  HD13 A ILE A 1 301 ? -26.07185 -20.35824 -25.05706 0.717 16.80484 ? 1760 ILE A HD13 1 
ATOM   4760 H  HD13 B ILE A 1 301 ? -26.08972 -22.11740 -27.62792 0.283 18.24185 ? 1760 ILE A HD13 1 
ATOM   4761 N  N    . PRO A 1 302 ? -30.91958 -23.17188 -26.93410 1.000 15.39660 ? 1761 PRO A N    1 
ATOM   4762 C  CA   . PRO A 1 302 ? -32.35048 -23.44638 -26.73035 1.000 16.11774 ? 1761 PRO A CA   1 
ATOM   4763 C  C    . PRO A 1 302 ? -32.82162 -22.89833 -25.38239 1.000 15.61768 ? 1761 PRO A C    1 
ATOM   4764 O  O    . PRO A 1 302 ? -32.09518 -22.20858 -24.65661 1.000 15.44398 ? 1761 PRO A O    1 
ATOM   4765 C  CB   . PRO A 1 302 ? -32.37627 -24.97990 -26.77527 1.000 16.68360 ? 1761 PRO A CB   1 
ATOM   4766 C  CG   . PRO A 1 302 ? -31.08071 -25.38100 -26.19123 1.000 16.90468 ? 1761 PRO A CG   1 
ATOM   4767 C  CD   . PRO A 1 302 ? -30.09028 -24.37823 -26.71216 1.000 16.37304 ? 1761 PRO A CD   1 
ATOM   4768 H  HA   . PRO A 1 302 ? -32.90512 -23.07491 -27.43411 1.000 19.34409 ? 1761 PRO A HA   1 
ATOM   4769 H  HB2  . PRO A 1 302 ? -33.11734 -25.31650 -26.24762 1.000 20.02312 ? 1761 PRO A HB2  1 
ATOM   4770 H  HB3  . PRO A 1 302 ? -32.45635 -25.28530 -27.69245 1.000 20.02312 ? 1761 PRO A HB3  1 
ATOM   4771 H  HG2  . PRO A 1 302 ? -31.13043 -25.34804 -25.22307 1.000 20.28841 ? 1761 PRO A HG2  1 
ATOM   4772 H  HG3  . PRO A 1 302 ? -30.85102 -26.27766 -26.48130 1.000 20.28841 ? 1761 PRO A HG3  1 
ATOM   4773 H  HD2  . PRO A 1 302 ? -29.39606 -24.20517 -26.05717 1.000 19.65044 ? 1761 PRO A HD2  1 
ATOM   4774 H  HD3  . PRO A 1 302 ? -29.69371 -24.68317 -27.54322 1.000 19.65044 ? 1761 PRO A HD3  1 
ATOM   4775 N  N    . SER A 1 303 ? -34.09771 -23.17665 -25.06510 1.000 15.51504 ? 1762 SER A N    1 
ATOM   4776 C  CA   . SER A 1 303 ? -34.68038 -22.64265 -23.83953 1.000 15.96509 ? 1762 SER A CA   1 
ATOM   4777 C  C    . SER A 1 303 ? -34.11556 -23.29103 -22.57746 1.000 15.52293 ? 1762 SER A C    1 
ATOM   4778 O  O    . SER A 1 303 ? -34.19177 -22.68647 -21.50582 1.000 16.01773 ? 1762 SER A O    1 
ATOM   4779 C  CB   . SER A 1 303 ? -36.21525 -22.73044 -23.88687 1.000 17.69425 ? 1762 SER A CB   1 
ATOM   4780 O  OG   . SER A 1 303 ? -36.61601 -24.08112 -23.99234 1.000 19.09968 ? 1762 SER A OG   1 
ATOM   4781 H  H    . SER A 1 303 ? -34.62900 -23.66164 -25.53640 1.000 18.62084 ? 1762 SER A H    1 
ATOM   4782 H  HA   . SER A 1 303 ? -34.46084 -21.69966 -23.78059 1.000 19.16091 ? 1762 SER A HA   1 
ATOM   4783 H  HB2  . SER A 1 303 ? -36.58236 -22.35071 -23.07327 1.000 21.23589 ? 1762 SER A HB2  1 
ATOM   4784 H  HB3  . SER A 1 303 ? -36.53985 -22.23958 -24.65797 1.000 21.23589 ? 1762 SER A HB3  1 
ATOM   4785 H  HG   . SER A 1 303 ? -37.45432 -24.13155 -24.00968 1.000 22.92241 ? 1762 SER A HG   1 
ATOM   4786 N  N    . HIS A 1 304 ? -33.53590 -24.48981 -22.67150 1.000 15.07814 ? 1763 HIS A N    1 
ATOM   4787 C  CA   . HIS A 1 304 ? -32.78708 -25.06916 -21.55624 1.000 15.45187 ? 1763 HIS A CA   1 
ATOM   4788 C  C    . HIS A 1 304 ? -31.70386 -25.97071 -22.13196 1.000 15.04393 ? 1763 HIS A C    1 
ATOM   4789 O  O    . HIS A 1 304 ? -31.90144 -26.61382 -23.16757 1.000 15.27817 ? 1763 HIS A O    1 
ATOM   4790 C  CB   . HIS A 1 304 ? -33.68708 -25.83895 -20.56019 1.000 16.75729 ? 1763 HIS A CB   1 
ATOM   4791 C  CG   . HIS A 1 304 ? -34.27983 -27.08576 -21.13150 1.000 17.71004 ? 1763 HIS A CG   1 
ATOM   4792 N  ND1  . HIS A 1 304 ? -35.49429 -27.09023 -21.78276 1.000 18.06271 ? 1763 HIS A ND1  1 
ATOM   4793 C  CD2  . HIS A 1 304 ? -33.83572 -28.36417 -21.14575 1.000 18.47066 ? 1763 HIS A CD2  1 
ATOM   4794 C  CE1  . HIS A 1 304 ? -35.76442 -28.31693 -22.18725 1.000 18.45486 ? 1763 HIS A CE1  1 
ATOM   4795 N  NE2  . HIS A 1 304 ? -34.76479 -29.10498 -21.83324 1.000 19.24443 ? 1763 HIS A NE2  1 
ATOM   4796 H  H    . HIS A 1 304 ? -33.56242 -24.98756 -23.37231 1.000 18.09657 ? 1763 HIS A H    1 
ATOM   4797 H  HA   . HIS A 1 304 ? -32.36325 -24.36062 -21.04708 1.000 18.54504 ? 1763 HIS A HA   1 
ATOM   4798 H  HB2  . HIS A 1 304 ? -33.15594 -26.08945 -19.78815 1.000 20.11155 ? 1763 HIS A HB2  1 
ATOM   4799 H  HB3  . HIS A 1 304 ? -34.41694 -25.26118 -20.28743 1.000 20.11155 ? 1763 HIS A HB3  1 
ATOM   4800 H  HD2  . HIS A 1 304 ? -33.04984 -28.68086 -20.76234 1.000 22.16758 ? 1763 HIS A HD2  1 
ATOM   4801 H  HE1  . HIS A 1 304 ? -36.52961 -28.58210 -22.64450 1.000 22.14863 ? 1763 HIS A HE1  1 
ATOM   4802 H  HE2  . HIS A 1 304 ? -34.70572 -29.94547 -22.00552 1.000 23.09611 ? 1763 HIS A HE2  1 
ATOM   4803 N  N    . MET A 1 305 ? -30.54948 -26.01070 -21.46483 1.000 14.73863 ? 1764 MET A N    1 
ATOM   4804 C  CA   . MET A 1 305 ? -29.51405 -26.95102 -21.84861 1.000 14.36753 ? 1764 MET A CA   1 
ATOM   4805 C  C    . MET A 1 305 ? -29.83340 -28.33023 -21.25026 1.000 14.45439 ? 1764 MET A C    1 
ATOM   4806 O  O    . MET A 1 305 ? -30.63442 -28.44808 -20.32864 1.000 14.78337 ? 1764 MET A O    1 
ATOM   4807 C  CB   . MET A 1 305 ? -28.17270 -26.41885 -21.35981 1.000 14.85970 ? 1764 MET A CB   1 
ATOM   4808 C  CG   . MET A 1 305 ? -27.79792 -25.11921 -22.08308 1.000 16.80993 ? 1764 MET A CG   1 
ATOM   4809 S  SD   . MET A 1 305 ? -27.74563 -25.19886 -23.85996 1.000 19.06546 ? 1764 MET A SD   1 
ATOM   4810 C  CE   . MET A 1 305 ? -26.29430 -26.26227 -24.06607 1.000 19.21022 ? 1764 MET A CE   1 
ATOM   4811 H  H    . MET A 1 305 ? -30.35037 -25.50783 -20.79620 1.000 17.68915 ? 1764 MET A H    1 
ATOM   4812 H  HA   . MET A 1 305 ? -29.45341 -27.04650 -22.81200 1.000 17.24384 ? 1764 MET A HA   1 
ATOM   4813 H  HB2  . MET A 1 305 ? -28.22571 -26.23694 -20.40849 1.000 17.83444 ? 1764 MET A HB2  1 
ATOM   4814 H  HB3  . MET A 1 305 ? -27.48219 -27.07753 -21.53366 1.000 17.83444 ? 1764 MET A HB3  1 
ATOM   4815 H  HG2  . MET A 1 305 ? -28.45065 -24.44174 -21.84668 1.000 20.17471 ? 1764 MET A HG2  1 
ATOM   4816 H  HG3  . MET A 1 305 ? -26.91588 -24.84902 -21.78326 1.000 20.17471 ? 1764 MET A HG3  1 
ATOM   4817 H  HE1  . MET A 1 305 ? -26.13719 -26.40212 -25.01299 1.000 23.05506 ? 1764 MET A HE1  1 
ATOM   4818 H  HE2  . MET A 1 305 ? -25.52548 -25.82879 -23.66369 1.000 23.05506 ? 1764 MET A HE2  1 
ATOM   4819 H  HE3  . MET A 1 305 ? -26.46098 -27.11221 -23.62936 1.000 23.05506 ? 1764 MET A HE3  1 
ATOM   4820 N  N    . PRO A 1 306 ? -29.22031 -29.39821 -21.77687 1.000 14.70442 ? 1765 PRO A N    1 
ATOM   4821 C  CA   . PRO A 1 306 ? -29.66103 -30.75007 -21.38652 1.000 15.12552 ? 1765 PRO A CA   1 
ATOM   4822 C  C    . PRO A 1 306 ? -29.46355 -31.13312 -19.92865 1.000 15.44661 ? 1765 PRO A C    1 
ATOM   4823 O  O    . PRO A 1 306 ? -30.25402 -31.94224 -19.42294 1.000 16.98363 ? 1765 PRO A O    1 
ATOM   4824 C  CB   . PRO A 1 306 ? -28.85379 -31.67409 -22.31775 1.000 16.00457 ? 1765 PRO A CB   1 
ATOM   4825 C  CG   . PRO A 1 306 ? -28.64071 -30.85248 -23.52108 1.000 16.27829 ? 1765 PRO A CG   1 
ATOM   4826 C  CD   . PRO A 1 306 ? -28.44844 -29.42134 -23.03355 1.000 15.40450 ? 1765 PRO A CD   1 
ATOM   4827 H  HA   . PRO A 1 306 ? -30.60935 -30.81367 -21.58029 1.000 18.15342 ? 1765 PRO A HA   1 
ATOM   4828 H  HB2  . PRO A 1 306 ? -28.01111 -31.91598 -21.90268 1.000 19.20828 ? 1765 PRO A HB2  1 
ATOM   4829 H  HB3  . PRO A 1 306 ? -29.36410 -32.47314 -22.52268 1.000 19.20828 ? 1765 PRO A HB3  1 
ATOM   4830 H  HG2  . PRO A 1 306 ? -27.85084 -31.16258 -23.99102 1.000 19.53674 ? 1765 PRO A HG2  1 
ATOM   4831 H  HG3  . PRO A 1 306 ? -29.41688 -30.91524 -24.09945 1.000 19.53674 ? 1765 PRO A HG3  1 
ATOM   4832 H  HD2  . PRO A 1 306 ? -27.51113 -29.23368 -22.86878 1.000 18.48820 ? 1765 PRO A HD2  1 
ATOM   4833 H  HD3  . PRO A 1 306 ? -28.80666 -28.78575 -23.67276 1.000 18.48820 ? 1765 PRO A HD3  1 
ATOM   4834 N  N    . PHE A 1 307 ? -28.42850 -30.64995 -19.23955 1.000 14.25173 ? 1766 PHE A N    1 
ATOM   4835 C  CA   . PHE A 1 307 ? -28.05566 -31.26411 -17.96796 1.000 13.04369 ? 1766 PHE A CA   1 
ATOM   4836 C  C    . PHE A 1 307 ? -28.40469 -30.47986 -16.71174 1.000 13.33846 ? 1766 PHE A C    1 
ATOM   4837 O  O    . PHE A 1 307 ? -28.84598 -31.08050 -15.73109 1.000 14.44386 ? 1766 PHE A O    1 
ATOM   4838 C  CB   . PHE A 1 307 ? -26.56193 -31.61536 -17.98056 1.000 13.37794 ? 1766 PHE A CB   1 
ATOM   4839 C  CG   . PHE A 1 307 ? -26.24493 -32.70948 -18.94474 1.000 14.44649 ? 1766 PHE A CG   1 
ATOM   4840 C  CD1  . PHE A 1 307 ? -26.64424 -33.99912 -18.68051 1.000 15.87298 ? 1766 PHE A CD1  1 
ATOM   4841 C  CD2  . PHE A 1 307 ? -25.66039 -32.42862 -20.16803 1.000 15.20448 ? 1766 PHE A CD2  1 
ATOM   4842 C  CE1  . PHE A 1 307 ? -26.39731 -35.02673 -19.59328 1.000 16.88889 ? 1766 PHE A CE1  1 
ATOM   4843 C  CE2  . PHE A 1 307 ? -25.41853 -33.43664 -21.09420 1.000 16.38619 ? 1766 PHE A CE2  1 
ATOM   4844 C  CZ   . PHE A 1 307 ? -25.78140 -34.74478 -20.80059 1.000 16.99153 ? 1766 PHE A CZ   1 
ATOM   4845 H  H    . PHE A 1 307 ? -27.94113 -29.98467 -19.48345 1.000 17.10487 ? 1766 PHE A H    1 
ATOM   4846 H  HA   . PHE A 1 307 ? -28.56126 -32.08789 -17.88631 1.000 15.65523 ? 1766 PHE A HA   1 
ATOM   4847 H  HB2  . PHE A 1 307 ? -26.05338 -30.83011 -18.23679 1.000 16.05633 ? 1766 PHE A HB2  1 
ATOM   4848 H  HB3  . PHE A 1 307 ? -26.29709 -31.90751 -17.09433 1.000 16.05633 ? 1766 PHE A HB3  1 
ATOM   4849 H  HD1  . PHE A 1 307 ? -27.08438 -34.18909 -17.88359 1.000 19.05037 ? 1766 PHE A HD1  1 
ATOM   4850 H  HD2  . PHE A 1 307 ? -25.42602 -31.55233 -20.37318 1.000 18.24817 ? 1766 PHE A HD2  1 
ATOM   4851 H  HE1  . PHE A 1 307 ? -26.64634 -35.89948 -19.39033 1.000 20.26946 ? 1766 PHE A HE1  1 
ATOM   4852 H  HE2  . PHE A 1 307 ? -25.01509 -33.23578 -21.90771 1.000 19.66623 ? 1766 PHE A HE2  1 
ATOM   4853 H  HZ   . PHE A 1 307 ? -25.61188 -35.42613 -21.41044 1.000 20.39263 ? 1766 PHE A HZ   1 
ATOM   4854 N  N    . SER A 1 308 ? -28.20097 -29.16878 -16.66636 1.000 12.66206 ? 1767 SER A N    1 
ATOM   4855 C  CA   . SER A 1 308 ? -28.45006 -28.46781 -15.41651 1.000 11.97514 ? 1767 SER A CA   1 
ATOM   4856 C  C    . SER A 1 308 ? -29.90899 -28.60553 -15.00710 1.000 12.17253 ? 1767 SER A C    1 
ATOM   4857 O  O    . SER A 1 308 ? -30.81857 -28.42641 -15.81894 1.000 12.55152 ? 1767 SER A O    1 
ATOM   4858 C  CB   . SER A 1 308 ? -28.10442 -26.98089 -15.54558 1.000 12.31992 ? 1767 SER A CB   1 
ATOM   4859 O  OG   . SER A 1 308 ? -28.48283 -26.28525 -14.37377 1.000 12.36203 ? 1767 SER A OG   1 
ATOM   4860 H  H    . SER A 1 308 ? -27.92918 -28.68110 -17.32050 1.000 15.19727 ? 1767 SER A H    1 
ATOM   4861 H  HA   . SER A 1 308 ? -27.88713 -28.85621 -14.72865 1.000 14.37297 ? 1767 SER A HA   1 
ATOM   4862 H  HB2  . SER A 1 308 ? -27.14782 -26.88708 -15.67600 1.000 14.78670 ? 1767 SER A HB2  1 
ATOM   4863 H  HB3  . SER A 1 308 ? -28.58076 -26.60851 -16.30410 1.000 14.78670 ? 1767 SER A HB3  1 
ATOM   4864 H  HG   . SER A 1 308 ? -28.07262 -26.59620 -13.70996 1.000 14.83723 ? 1767 SER A HG   1 
ATOM   4865 N  N    . LYS A 1 309 ? -30.12336 -28.88633 -13.72291 1.000 12.48310 ? 1768 LYS A N    1 
ATOM   4866 C  CA   . LYS A 1 309 ? -31.47885 -28.94040 -13.20745 1.000 13.82536 ? 1768 LYS A CA   1 
ATOM   4867 C  C    . LYS A 1 309 ? -32.15103 -27.57804 -13.20510 1.000 13.93064 ? 1768 LYS A C    1 
ATOM   4868 O  O    . LYS A 1 309 ? -33.36983 -27.50233 -13.01270 1.000 15.33343 ? 1768 LYS A O    1 
ATOM   4869 C  CB   . LYS A 1 309 ? -31.52511 -29.57116 -11.81409 1.000 14.55177 ? 1768 LYS A CB   1 
ATOM   4870 C  CG   . LYS A 1 309 ? -31.06323 -31.00354 -11.69115 1.000 15.49398 ? 1768 LYS A CG   1 
ATOM   4871 C  CD   . LYS A 1 309 ? -31.36215 -31.51587 -10.29350 1.000 17.32052 ? 1768 LYS A CD   1 
ATOM   4872 C  CE   . LYS A 1 309 ? -30.76558 -32.86165 -10.01826 1.000 18.73648 ? 1768 LYS A CE   1 
ATOM   4873 N  NZ   . LYS A 1 309 ? -31.06846 -33.32976 -8.61314  1.000 19.69712 ? 1768 LYS A NZ   1 
ATOM   4874 H  H    . LYS A 1 309 ? -29.50831 -29.04592 -13.14339 1.000 14.98251 ? 1768 LYS A H    1 
ATOM   4875 H  HA   . LYS A 1 309 ? -31.99753 -29.52656 -13.78042 1.000 16.59323 ? 1768 LYS A HA   1 
ATOM   4876 H  HB2  . LYS A 1 309 ? -30.96156 -29.04223 -11.22796 1.000 17.46492 ? 1768 LYS A HB2  1 
ATOM   4877 H  HB3  . LYS A 1 309 ? -32.44391 -29.54394 -11.50429 1.000 17.46492 ? 1768 LYS A HB3  1 
ATOM   4878 H  HG2  . LYS A 1 309 ? -31.53327 -31.55679 -12.33448 1.000 18.59558 ? 1768 LYS A HG2  1 
ATOM   4879 H  HG3  . LYS A 1 309 ? -30.10696 -31.05490 -11.84545 1.000 18.59558 ? 1768 LYS A HG3  1 
ATOM   4880 H  HD2  . LYS A 1 309 ? -31.00015 -30.89162 -9.64529  1.000 20.78742 ? 1768 LYS A HD2  1 
ATOM   4881 H  HD3  . LYS A 1 309 ? -32.32319 -31.58820 -10.18360 1.000 20.78742 ? 1768 LYS A HD3  1 
ATOM   4882 H  HE2  . LYS A 1 309 ? -31.13339 -33.50857 -10.64045 1.000 22.48657 ? 1768 LYS A HE2  1 
ATOM   4883 H  HE3  . LYS A 1 309 ? -29.80236 -32.81243 -10.12163 1.000 22.48657 ? 1768 LYS A HE3  1 
ATOM   4884 H  HZ1  . LYS A 1 309 ? -30.72527 -32.75994 -8.02185  1.000 23.63934 ? 1768 LYS A HZ1  1 
ATOM   4885 H  HZ2  . LYS A 1 309 ? -31.94879 -33.37721 -8.49122  1.000 23.63934 ? 1768 LYS A HZ2  1 
ATOM   4886 H  HZ3  . LYS A 1 309 ? -30.71427 -34.13492 -8.47754  1.000 23.63934 ? 1768 LYS A HZ3  1 
ATOM   4887 N  N    . ALA A 1 310 ? -31.41617 -26.49572 -13.42391 1.000 13.32004 ? 1769 ALA A N    1 
ATOM   4888 C  CA   . ALA A 1 310 ? -32.07807 -25.19987 -13.54033 1.000 13.15949 ? 1769 ALA A CA   1 
ATOM   4889 C  C    . ALA A 1 310 ? -33.15589 -25.23643 -14.61318 1.000 13.62797 ? 1769 ALA A C    1 
ATOM   4890 O  O    . ALA A 1 310 ? -34.20612 -24.58843 -14.47524 1.000 13.65166 ? 1769 ALA A O    1 
ATOM   4891 C  CB   . ALA A 1 310 ? -31.04252 -24.13743 -13.87327 1.000 13.47006 ? 1769 ALA A CB   1 
ATOM   4892 H  H    . ALA A 1 310 ? -30.56027 -26.48199 -13.50662 1.000 15.98684 ? 1769 ALA A H    1 
ATOM   4893 H  HA   . ALA A 1 310 ? -32.49696 -24.97211 -12.69561 1.000 15.79419 ? 1769 ALA A HA   1 
ATOM   4894 H  HB1  . ALA A 1 310 ? -31.48345 -23.27582 -13.93748 1.000 16.16686 ? 1769 ALA A HB1  1 
ATOM   4895 H  HB2  . ALA A 1 310 ? -30.37491 -24.11576 -13.16990 1.000 16.16686 ? 1769 ALA A HB2  1 
ATOM   4896 H  HB3  . ALA A 1 310 ? -30.62398 -24.35872 -14.71989 1.000 16.16686 ? 1769 ALA A HB3  1 
ATOM   4897 N  N    . HIS A 1 311 ? -32.90334 -25.97144 -15.70069 1.000 13.40163 ? 1770 HIS A N    1 
ATOM   4898 C  CA   . HIS A 1 311 ? -33.86976 -26.17857 -16.77385 1.000 13.96222 ? 1770 HIS A CA   1 
ATOM   4899 C  C    . HIS A 1 311 ? -34.31387 -24.86025 -17.42352 1.000 13.21476 ? 1770 HIS A C    1 
ATOM   4900 O  O    . HIS A 1 311 ? -35.45740 -24.72138 -17.83856 1.000 14.12803 ? 1770 HIS A O    1 
ATOM   4901 C  CB   . HIS A 1 311 ? -35.06515 -27.02085 -16.28774 1.000 15.75717 ? 1770 HIS A CB   1 
ATOM   4902 C  CG   . HIS A 1 311 ? -35.73348 -27.78730 -17.37452 1.000 17.97060 ? 1770 HIS A CG   1 
ATOM   4903 N  ND1  . HIS A 1 311 ? -35.26932 -29.00421 -17.82857 1.000 19.96294 ? 1770 HIS A ND1  1 
ATOM   4904 C  CD2  . HIS A 1 311 ? -36.83562 -27.50551 -18.10731 1.000 19.09968 ? 1770 HIS A CD2  1 
ATOM   4905 C  CE1  . HIS A 1 311 ? -36.05146 -29.42915 -18.80441 1.000 20.63144 ? 1770 HIS A CE1  1 
ATOM   4906 N  NE2  . HIS A 1 311 ? -37.02040 -28.55114 -18.97741 1.000 20.62881 ? 1770 HIS A NE2  1 
ATOM   4907 H  H    . HIS A 1 311 ? -32.15488 -26.37121 -15.84062 1.000 16.08475 ? 1770 HIS A H    1 
ATOM   4908 H  HA   . HIS A 1 311 ? -33.43832 -26.68203 -17.48187 1.000 16.75746 ? 1770 HIS A HA   1 
ATOM   4909 H  HB2  . HIS A 1 311 ? -34.75115 -27.65658 -15.62581 1.000 18.91140 ? 1770 HIS A HB2  1 
ATOM   4910 H  HB3  . HIS A 1 311 ? -35.72458 -26.42917 -15.89282 1.000 18.91140 ? 1770 HIS A HB3  1 
ATOM   4911 H  HD1  . HIS A 1 311 ? -34.58052 -29.41996 -17.52475 1.000 23.95832 ? 1770 HIS A HD1  1 
ATOM   4912 H  HD2  . HIS A 1 311 ? -37.36782 -26.74628 -18.03507 1.000 22.92241 ? 1770 HIS A HD2  1 
ATOM   4913 H  HE1  . HIS A 1 311 ? -35.93803 -30.21527 -19.28819 1.000 24.76053 ? 1770 HIS A HE1  1 
ATOM   4914 N  N    . TRP A 1 312 ? -33.41821 -23.87658 -17.50688 1.000 12.28834 ? 1771 TRP A N    1 
ATOM   4915 C  CA   . TRP A 1 312 ? -33.65624 -22.62021 -18.21274 1.000 12.14095 ? 1771 TRP A CA   1 
ATOM   4916 C  C    . TRP A 1 312 ? -32.27724 -22.03206 -18.50931 1.000 12.16990 ? 1771 TRP A C    1 
ATOM   4917 O  O    . TRP A 1 312 ? -31.27117 -22.46804 -17.94913 1.000 12.60153 ? 1771 TRP A O    1 
ATOM   4918 C  CB   . TRP A 1 312 ? -34.53629 -21.65246 -17.38094 1.000 12.03567 ? 1771 TRP A CB   1 
ATOM   4919 C  CG   . TRP A 1 312 ? -33.79773 -20.92055 -16.29493 1.000 11.56457 ? 1771 TRP A CG   1 
ATOM   4920 C  CD1  . TRP A 1 312 ? -33.45176 -21.38990 -15.04418 1.000 11.65405 ? 1771 TRP A CD1  1 
ATOM   4921 C  CD2  . TRP A 1 312 ? -33.28473 -19.59131 -16.37149 1.000 11.80933 ? 1771 TRP A CD2  1 
ATOM   4922 N  NE1  . TRP A 1 312 ? -32.73135 -20.43192 -14.35923 1.000 11.68826 ? 1771 TRP A NE1  1 
ATOM   4923 C  CE2  . TRP A 1 312 ? -32.63213 -19.31780 -15.15224 1.000 11.54877 ? 1771 TRP A CE2  1 
ATOM   4924 C  CE3  . TRP A 1 312 ? -33.34004 -18.59901 -17.34402 1.000 12.14095 ? 1771 TRP A CE3  1 
ATOM   4925 C  CZ2  . TRP A 1 312 ? -32.02621 -18.09974 -14.89725 1.000 11.64615 ? 1771 TRP A CZ2  1 
ATOM   4926 C  CZ3  . TRP A 1 312 ? -32.75426 -17.37576 -17.07351 1.000 11.75406 ? 1771 TRP A CZ3  1 
ATOM   4927 C  CH2  . TRP A 1 312 ? -32.10805 -17.14032 -15.86900 1.000 11.50929 ? 1771 TRP A CH2  1 
ATOM   4928 H  H    . TRP A 1 312 ? -32.63684 -23.91476 -17.14967 1.000 14.74880 ? 1771 TRP A H    1 
ATOM   4929 H  HA   . TRP A 1 312 ? -34.12646 -22.77460 -19.04697 1.000 14.57194 ? 1771 TRP A HA   1 
ATOM   4930 H  HB2  . TRP A 1 312 ? -34.91474 -20.98789 -17.97762 1.000 14.44560 ? 1771 TRP A HB2  1 
ATOM   4931 H  HB3  . TRP A 1 312 ? -35.24572 -22.16315 -16.96046 1.000 14.44560 ? 1771 TRP A HB3  1 
ATOM   4932 H  HD1  . TRP A 1 312 ? -33.67197 -22.22978 -14.71100 1.000 13.98766 ? 1771 TRP A HD1  1 
ATOM   4933 H  HE1  . TRP A 1 312 ? -32.40118 -20.51907 -13.56993 1.000 14.02871 ? 1771 TRP A HE1  1 
ATOM   4934 H  HE3  . TRP A 1 312 ? -33.76158 -18.75448 -18.15829 1.000 14.57193 ? 1771 TRP A HE3  1 
ATOM   4935 H  HZ2  . TRP A 1 312 ? -31.58088 -17.93981 -14.09662 1.000 13.97818 ? 1771 TRP A HZ2  1 
ATOM   4936 H  HZ3  . TRP A 1 312 ? -32.79433 -16.69921 -17.71036 1.000 14.10767 ? 1771 TRP A HZ3  1 
ATOM   4937 H  HH2  . TRP A 1 312 ? -31.72031 -16.30858 -15.71807 1.000 13.81395 ? 1771 TRP A HH2  1 
ATOM   4938 N  N    . THR A 1 313 ? -32.23393 -21.01788 -19.38544 1.000 12.05673 ? 1772 THR A N    1 
ATOM   4939 C  CA   . THR A 1 313 ? -30.96576 -20.30652 -19.59975 1.000 11.99356 ? 1772 THR A CA   1 
ATOM   4940 C  C    . THR A 1 313 ? -31.21845 -18.89098 -20.09065 1.000 12.12779 ? 1772 THR A C    1 
ATOM   4941 O  O    . THR A 1 313 ? -32.07038 -18.67685 -20.96597 1.000 13.02526 ? 1772 THR A O    1 
ATOM   4942 C  CB   . THR A 1 313 ? -30.02071 -21.03366 -20.57388 1.000 12.13832 ? 1772 THR A CB   1 
ATOM   4943 O  OG1  . THR A 1 313 ? -28.90226 -20.16862 -20.88145 1.000 12.50678 ? 1772 THR A OG1  1 
ATOM   4944 C  CG2  . THR A 1 313 ? -30.69698 -21.40024 -21.87669 1.000 12.43835 ? 1772 THR A CG2  1 
ATOM   4945 H  H    . THR A 1 313 ? -32.90041 -20.73479 -19.84940 1.000 14.47087 ? 1772 THR A H    1 
ATOM   4946 H  HA   . THR A 1 313 ? -30.52963 -20.24126 -18.73579 1.000 14.39507 ? 1772 THR A HA   1 
ATOM   4947 H  HB   . THR A 1 313 ? -29.72899 -21.85590 -20.14995 1.000 14.56878 ? 1772 THR A HB   1 
ATOM   4948 H  HG1  . THR A 1 313 ? -28.41170 -20.08184 -20.20512 1.000 15.01093 ? 1772 THR A HG1  1 
ATOM   4949 H  HG21 . THR A 1 313 ? -30.05810 -21.81593 -22.47663 1.000 14.92882 ? 1772 THR A HG21 1 
ATOM   4950 H  HG22 . THR A 1 313 ? -31.42297 -22.02164 -21.71026 1.000 14.92882 ? 1772 THR A HG22 1 
ATOM   4951 H  HG23 . THR A 1 313 ? -31.05475 -20.60429 -22.30021 1.000 14.92882 ? 1772 THR A HG23 1 
ATOM   4952 N  N    . PRO A 1 314 ? -30.45908 -17.90942 -19.58749 1.000 11.88829 ? 1773 PRO A N    1 
ATOM   4953 C  CA   . PRO A 1 314 ? -30.65021 -16.52833 -20.06581 1.000 12.14095 ? 1773 PRO A CA   1 
ATOM   4954 C  C    . PRO A 1 314 ? -30.09347 -16.29946 -21.44139 1.000 12.45414 ? 1773 PRO A C    1 
ATOM   4955 O  O    . PRO A 1 314 ? -30.38391 -15.26138 -22.03872 1.000 13.04632 ? 1773 PRO A O    1 
ATOM   4956 C  CB   . PRO A 1 314 ? -29.90742 -15.68999 -19.02614 1.000 12.19622 ? 1773 PRO A CB   1 
ATOM   4957 C  CG   . PRO A 1 314 ? -28.76750 -16.60422 -18.57528 1.000 12.10674 ? 1773 PRO A CG   1 
ATOM   4958 C  CD   . PRO A 1 314 ? -29.45247 -17.97420 -18.50730 1.000 12.42782 ? 1773 PRO A CD   1 
ATOM   4959 H  HA   . PRO A 1 314 ? -31.59035 -16.29003 -20.04953 1.000 14.57194 ? 1773 PRO A HA   1 
ATOM   4960 H  HB2  . PRO A 1 314 ? -29.56756 -14.87672 -19.43108 1.000 14.63826 ? 1773 PRO A HB2  1 
ATOM   4961 H  HB3  . PRO A 1 314 ? -30.49693 -15.47154 -18.28746 1.000 14.63826 ? 1773 PRO A HB3  1 
ATOM   4962 H  HG2  . PRO A 1 314 ? -28.04757 -16.59781 -19.22533 1.000 14.53088 ? 1773 PRO A HG2  1 
ATOM   4963 H  HG3  . PRO A 1 314 ? -28.43305 -16.32973 -17.70713 1.000 14.53088 ? 1773 PRO A HG3  1 
ATOM   4964 H  HD2  . PRO A 1 314 ? -28.81524 -18.68666 -18.67234 1.000 14.91619 ? 1773 PRO A HD2  1 
ATOM   4965 H  HD3  . PRO A 1 314 ? -29.87922 -18.10374 -17.64590 1.000 14.91619 ? 1773 PRO A HD3  1 
ATOM   4966 N  N    . PHE A 1 315 ? -29.31675 -17.23565 -21.97100 1.000 12.35413 ? 1774 PHE A N    1 
ATOM   4967 C  CA   . PHE A 1 315 ? -28.73167 -17.07439 -23.28303 1.000 12.26465 ? 1774 PHE A CA   1 
ATOM   4968 C  C    . PHE A 1 315 ? -29.61081 -17.64253 -24.38862 1.000 13.18581 ? 1774 PHE A C    1 
ATOM   4969 O  O    . PHE A 1 315 ? -29.18710 -17.65044 -25.54345 1.000 13.61744 ? 1774 PHE A O    1 
ATOM   4970 C  CB   . PHE A 1 315 ? -27.32842 -17.71319 -23.32579 1.000 12.23306 ? 1774 PHE A CB   1 
ATOM   4971 C  CG   . PHE A 1 315 ? -26.38413 -17.17284 -22.28788 1.000 11.24084 ? 1774 PHE A CG   1 
ATOM   4972 C  CD1  . PHE A 1 315 ? -25.72446 -15.95763 -22.49420 1.000 11.16978 ? 1774 PHE A CD1  1 
ATOM   4973 C  CD2  . PHE A 1 315 ? -26.12911 -17.87414 -21.11901 1.000 11.51982 ? 1774 PHE A CD2  1 
ATOM   4974 C  CE1  . PHE A 1 315 ? -24.87103 -15.45766 -21.56201 1.000 11.12241 ? 1774 PHE A CE1  1 
ATOM   4975 C  CE2  . PHE A 1 315 ? -25.25732 -17.38095 -20.17460 1.000 11.45666 ? 1774 PHE A CE2  1 
ATOM   4976 C  CZ   . PHE A 1 315 ? -24.61319 -16.17030 -20.40032 1.000 11.45666 ? 1774 PHE A CZ   1 
ATOM   4977 H  H    . PHE A 1 315 ? -29.11573 -17.97630 -21.58289 1.000 14.82776 ? 1774 PHE A H    1 
ATOM   4978 H  HA   . PHE A 1 315 ? -28.61575 -16.12817 -23.46227 1.000 14.72038 ? 1774 PHE A HA   1 
ATOM   4979 H  HB2  . PHE A 1 315 ? -27.41584 -18.66786 -23.17793 1.000 14.68247 ? 1774 PHE A HB2  1 
ATOM   4980 H  HB3  . PHE A 1 315 ? -26.93665 -17.54698 -24.19745 1.000 14.68247 ? 1774 PHE A HB3  1 
ATOM   4981 H  HD1  . PHE A 1 315 ? -25.87179 -15.48428 -23.28105 1.000 13.40653 ? 1774 PHE A HD1  1 
ATOM   4982 H  HD2  . PHE A 1 315 ? -26.55280 -18.68870 -20.97112 1.000 13.82658 ? 1774 PHE A HD2  1 
ATOM   4983 H  HE1  . PHE A 1 315 ? -24.45907 -14.63595 -21.70337 1.000 13.34969 ? 1774 PHE A HE1  1 
ATOM   4984 H  HE2  . PHE A 1 315 ? -25.10032 -17.85514 -19.39012 1.000 13.75079 ? 1774 PHE A HE2  1 
ATOM   4985 H  HZ   . PHE A 1 315 ? -24.01082 -15.83885 -19.77406 1.000 13.75079 ? 1774 PHE A HZ   1 
ATOM   4986 N  N    . GLU A 1 316 ? -30.81988 -18.09776 -24.06462 1.000 13.40952 ? 1775 GLU A N    1 
ATOM   4987 C  CA   . GLU A 1 316 ? -31.71228 -18.62398 -25.07706 1.000 14.35174 ? 1775 GLU A CA   1 
ATOM   4988 C  C    . GLU A 1 316 ? -31.79703 -17.67394 -26.26071 1.000 15.10183 ? 1775 GLU A C    1 
ATOM   4989 O  O    . GLU A 1 316 ? -31.98769 -16.46660 -26.08806 1.000 15.62031 ? 1775 GLU A O    1 
ATOM   4990 C  CB   . GLU A 1 316 ? -33.11389 -18.76558 -24.48251 1.000 16.07300 ? 1775 GLU A CB   1 
ATOM   4991 C  CG   . GLU A 1 316 ? -34.11145 -19.34763 -25.48235 1.000 17.59687 ? 1775 GLU A CG   1 
ATOM   4992 C  CD   . GLU A 1 316 ? -35.53078 -19.40136 -24.98663 1.000 19.27865 ? 1775 GLU A CD   1 
ATOM   4993 O  OE1  . GLU A 1 316 ? -35.74243 -19.27352 -23.76364 1.000 20.23139 ? 1775 GLU A OE1  1 
ATOM   4994 O  OE2  . GLU A 1 316 ? -36.41250 -19.68836 -25.82828 1.000 20.39457 ? 1775 GLU A OE2  1 
ATOM   4995 H  H    . GLU A 1 316 ? -31.14053 -18.11029 -23.26673 1.000 16.09423 ? 1775 GLU A H    1 
ATOM   4996 H  HA   . GLU A 1 316 ? -31.38320 -19.48643 -25.37503 1.000 17.22489 ? 1775 GLU A HA   1 
ATOM   4997 H  HB2  . GLU A 1 316 ? -33.07483 -19.35745 -23.71500 1.000 19.29040 ? 1775 GLU A HB2  1 
ATOM   4998 H  HB3  . GLU A 1 316 ? -33.43339 -17.89088 -24.21101 1.000 19.29040 ? 1775 GLU A HB3  1 
ATOM   4999 H  HG2  . GLU A 1 316 ? -34.10172 -18.80068 -26.28338 1.000 21.11904 ? 1775 GLU A HG2  1 
ATOM   5000 H  HG3  . GLU A 1 316 ? -33.84171 -20.25443 -25.69650 1.000 21.11904 ? 1775 GLU A HG3  1 
ATOM   5001 N  N    . GLY A 1 317 ? -31.68467 -18.22990 -27.45524 1.000 15.33344 ? 1776 GLY A N    1 
ATOM   5002 C  CA   . GLY A 1 317 ? -31.82181 -17.47099 -28.67119 1.000 15.79402 ? 1776 GLY A CA   1 
ATOM   5003 C  C    . GLY A 1 317 ? -30.53082 -16.93260 -29.24160 1.000 16.24144 ? 1776 GLY A C    1 
ATOM   5004 O  O    . GLY A 1 317 ? -30.52558 -16.47700 -30.39192 1.000 16.99416 ? 1776 GLY A O    1 
ATOM   5005 H  H    . GLY A 1 317 ? -31.52537 -19.06508 -27.58449 1.000 18.40292 ? 1776 GLY A H    1 
ATOM   5006 H  HA2  . GLY A 1 317 ? -32.22790 -18.03785 -29.34548 1.000 18.95562 ? 1776 GLY A HA2  1 
ATOM   5007 H  HA3  . GLY A 1 317 ? -32.40583 -16.71563 -28.50017 1.000 18.95562 ? 1776 GLY A HA3  1 
ATOM   5008 N  N    . GLN A 1 318 ? -29.45147 -16.92879 -28.47172 1.000 15.52820 ? 1777 GLN A N    1 
ATOM   5009 C  CA   . GLN A 1 318 ? -28.17265 -16.49102 -29.01625 1.000 15.89930 ? 1777 GLN A CA   1 
ATOM   5010 C  C    . GLN A 1 318 ? -27.60428 -17.53618 -29.97758 1.000 16.09669 ? 1777 GLN A C    1 
ATOM   5011 O  O    . GLN A 1 318 ? -27.65994 -18.74150 -29.72682 1.000 16.33619 ? 1777 GLN A O    1 
ATOM   5012 C  CB   . GLN A 1 318 ? -27.17206 -16.15937 -27.90678 1.000 16.57043 ? 1777 GLN A CB   1 
ATOM   5013 C  CG   . GLN A 1 318 ? -27.64238 -15.10384 -26.91674 1.000 17.18629 ? 1777 GLN A CG   1 
ATOM   5014 C  CD   . GLN A 1 318 ? -26.49515 -14.44540 -26.17409 1.000 18.40749 ? 1777 GLN A CD   1 
ATOM   5015 O  OE1  . GLN A 1 318 ? -25.38574 -14.97141 -26.14073 1.000 20.73408 ? 1777 GLN A OE1  1 
ATOM   5016 N  NE2  . GLN A 1 318 ? -26.79141 -13.37193 -25.45365 1.000 18.26800 ? 1777 GLN A NE2  1 
ATOM   5017 H  H    . GLN A 1 318 ? -29.43177 -17.16999 -27.64647 1.000 18.63664 ? 1777 GLN A H    1 
ATOM   5018 H  HA   . GLN A 1 318 ? -28.31209 -15.67243 -29.51762 1.000 19.08195 ? 1777 GLN A HA   1 
ATOM   5019 H  HB2  . GLN A 1 318 ? -26.98964 -16.96914 -27.40490 1.000 19.88731 ? 1777 GLN A HB2  1 
ATOM   5020 H  HB3  . GLN A 1 318 ? -26.35599 -15.83194 -28.31631 1.000 19.88731 ? 1777 GLN A HB3  1 
ATOM   5021 H  HG2  . GLN A 1 318 ? -28.12525 -14.41286 -27.39663 1.000 20.62635 ? 1777 GLN A HG2  1 
ATOM   5022 H  HG3  . GLN A 1 318 ? -28.22377 -15.52106 -26.26191 1.000 20.62635 ? 1777 GLN A HG3  1 
ATOM   5023 H  HE21 . GLN A 1 318 ? -27.60101 -13.08324 -25.42509 1.000 21.92440 ? 1777 GLN A HE21 1 
ATOM   5024 H  HE22 . GLN A 1 318 ? -26.17391 -12.96457 -25.01506 1.000 21.92440 ? 1777 GLN A HE22 1 
ATOM   5025 N  N    . LYS A 1 319 ? -27.04768 -17.05274 -31.08153 1.000 17.20998 ? 1778 LYS A N    1 
ATOM   5026 C  CA   A LYS A 1 319 ? -26.40451 -17.89039 -32.08393 0.505 18.11535 ? 1778 LYS A CA   1 
ATOM   5027 C  CA   B LYS A 1 319 ? -26.40739 -17.89994 -32.07588 0.495 18.40223 ? 1778 LYS A CA   1 
ATOM   5028 C  C    . LYS A 1 319 ? -24.93649 -18.03695 -31.71632 1.000 17.76004 ? 1778 LYS A C    1 
ATOM   5029 O  O    . LYS A 1 319 ? -24.25697 -17.03939 -31.45240 1.000 18.31011 ? 1778 LYS A O    1 
ATOM   5030 C  CB   A LYS A 1 319 ? -26.56564 -17.24072 -33.45837 0.505 19.85766 ? 1778 LYS A CB   1 
ATOM   5031 C  CB   B LYS A 1 319 ? -26.58534 -17.30276 -33.47053 0.495 20.63934 ? 1778 LYS A CB   1 
ATOM   5032 C  CG   A LYS A 1 319 ? -28.01587 -16.84305 -33.75435 0.505 21.97107 ? 1778 LYS A CG   1 
ATOM   5033 C  CG   B LYS A 1 319 ? -27.99439 -17.52617 -34.03379 0.495 23.08963 ? 1778 LYS A CG   1 
ATOM   5034 C  CD   A LYS A 1 319 ? -28.19902 -16.24115 -35.13817 0.505 23.81340 ? 1778 LYS A CD   1 
ATOM   5035 C  CD   B LYS A 1 319 ? -28.19246 -16.82965 -35.36437 0.495 25.38727 ? 1778 LYS A CD   1 
ATOM   5036 C  CE   A LYS A 1 319 ? -29.67565 -16.20237 -35.52028 0.505 25.18462 ? 1778 LYS A CE   1 
ATOM   5037 C  CE   B LYS A 1 319 ? -27.37087 -17.48445 -36.45736 0.495 26.91904 ? 1778 LYS A CE   1 
ATOM   5038 N  NZ   A LYS A 1 319 ? -29.90489 -16.54180 -36.94495 0.505 26.20842 ? 1778 LYS A NZ   1 
ATOM   5039 N  NZ   B LYS A 1 319 ? -27.74435 -16.97136 -37.80766 0.495 27.67702 ? 1778 LYS A NZ   1 
ATOM   5040 H  H    A LYS A 1 319 ? -27.02928 -16.21584 -31.27867 0.505 20.65477 ? 1778 LYS A H    1 
ATOM   5041 H  H    B LYS A 1 319 ? -27.02807 -16.21649 -31.28129 0.495 20.65477 ? 1778 LYS A H    1 
ATOM   5042 H  HA   A LYS A 1 319 ? -26.80030 -18.77534 -32.11744 0.505 21.74122 ? 1778 LYS A HA   1 
ATOM   5043 H  HA   B LYS A 1 319 ? -26.80477 -18.78474 -32.08610 0.495 22.08547 ? 1778 LYS A HA   1 
ATOM   5044 H  HB2  A LYS A 1 319 ? -26.02002 -16.43959 -33.49560 0.505 23.83199 ? 1778 LYS A HB2  1 
ATOM   5045 H  HB2  B LYS A 1 319 ? -26.42669 -16.34679 -33.42755 0.495 24.77000 ? 1778 LYS A HB2  1 
ATOM   5046 H  HB3  A LYS A 1 319 ? -26.28022 -17.86850 -34.14052 0.505 23.83199 ? 1778 LYS A HB3  1 
ATOM   5047 H  HB3  B LYS A 1 319 ? -25.95042 -17.71756 -34.07527 0.495 24.77000 ? 1778 LYS A HB3  1 
ATOM   5048 H  HG2  A LYS A 1 319 ? -28.57718 -17.63197 -33.69584 0.505 26.36809 ? 1778 LYS A HG2  1 
ATOM   5049 H  HG2  B LYS A 1 319 ? -28.13853 -18.47633 -34.16537 0.495 27.71035 ? 1778 LYS A HG2  1 
ATOM   5050 H  HG3  A LYS A 1 319 ? -28.30117 -16.18381 -33.10250 0.505 26.36809 ? 1778 LYS A HG3  1 
ATOM   5051 H  HG3  B LYS A 1 319 ? -28.64745 -17.17502 -33.40841 0.495 27.71035 ? 1778 LYS A HG3  1 
ATOM   5052 H  HD2  A LYS A 1 319 ? -27.85523 -15.33415 -35.14517 0.505 28.57888 ? 1778 LYS A HD2  1 
ATOM   5053 H  HD2  B LYS A 1 319 ? -29.12810 -16.87618 -35.61597 0.495 30.46752 ? 1778 LYS A HD2  1 
ATOM   5054 H  HD3  A LYS A 1 319 ? -27.72603 -16.78027 -35.79126 0.505 28.57888 ? 1778 LYS A HD3  1 
ATOM   5055 H  HD3  B LYS A 1 319 ? -27.91534 -15.90328 -35.28722 0.495 30.46752 ? 1778 LYS A HD3  1 
ATOM   5056 H  HE2  A LYS A 1 319 ? -30.16045 -16.84331 -34.97708 0.505 30.22434 ? 1778 LYS A HE2  1 
ATOM   5057 H  HE2  B LYS A 1 319 ? -26.43110 -17.29551 -36.30897 0.495 32.30564 ? 1778 LYS A HE2  1 
ATOM   5058 H  HE3  A LYS A 1 319 ? -30.01967 -15.30876 -35.36534 0.505 30.22434 ? 1778 LYS A HE3  1 
ATOM   5059 H  HE3  B LYS A 1 319 ? -27.52304 -18.44232 -36.44272 0.495 32.30564 ? 1778 LYS A HE3  1 
ATOM   5060 H  HZ1  A LYS A 1 319 ? -30.77510 -16.51100 -37.12899 0.505 31.45291 ? 1778 LYS A HZ1  1 
ATOM   5061 H  HZ1  B LYS A 1 319 ? -27.24967 -17.36866 -38.43179 0.495 33.21522 ? 1778 LYS A HZ1  1 
ATOM   5062 H  HZ2  A LYS A 1 319 ? -29.47825 -15.96210 -37.46843 0.505 31.45291 ? 1778 LYS A HZ2  1 
ATOM   5063 H  HZ2  B LYS A 1 319 ? -28.60326 -17.13870 -37.97002 0.495 33.21522 ? 1778 LYS A HZ2  1 
ATOM   5064 H  HZ3  A LYS A 1 319 ? -29.60252 -17.36139 -37.11506 0.505 31.45291 ? 1778 LYS A HZ3  1 
ATOM   5065 H  HZ3  B LYS A 1 319 ? -27.60870 -16.09266 -37.84763 0.495 33.21522 ? 1778 LYS A HZ3  1 
ATOM   5066 N  N    . VAL A 1 320 ? -24.47382 -19.27651 -31.66658 1.000 16.24144 ? 1779 VAL A N    1 
ATOM   5067 C  CA   . VAL A 1 320 ? -23.11524 -19.59866 -31.26826 1.000 15.77560 ? 1779 VAL A CA   1 
ATOM   5068 C  C    . VAL A 1 320 ? -22.48947 -20.45676 -32.35170 1.000 16.38356 ? 1779 VAL A C    1 
ATOM   5069 O  O    . VAL A 1 320 ? -23.16808 -21.03598 -33.20426 1.000 17.08365 ? 1779 VAL A O    1 
ATOM   5070 C  CB   . VAL A 1 320 ? -23.04690 -20.28723 -29.88750 1.000 15.50451 ? 1779 VAL A CB   1 
ATOM   5071 C  CG1  . VAL A 1 320 ? -23.36791 -19.26767 -28.77906 1.000 16.11511 ? 1779 VAL A CG1  1 
ATOM   5072 C  CG2  . VAL A 1 320 ? -23.97655 -21.48322 -29.81370 1.000 15.72559 ? 1779 VAL A CG2  1 
ATOM   5073 H  H    . VAL A 1 320 ? -24.94332 -19.96908 -31.86536 1.000 19.49253 ? 1779 VAL A H    1 
ATOM   5074 H  HA   . VAL A 1 320 ? -22.59535 -18.78243 -31.20190 1.000 18.93351 ? 1779 VAL A HA   1 
ATOM   5075 H  HB   . VAL A 1 320 ? -22.14694 -20.62227 -29.75070 1.000 18.60821 ? 1779 VAL A HB   1 
ATOM   5076 H  HG11 . VAL A 1 320 ? -23.31590 -19.71074 -27.91773 1.000 19.34093 ? 1779 VAL A HG11 1 
ATOM   5077 H  HG12 . VAL A 1 320 ? -22.72256 -18.54457 -28.81857 1.000 19.34093 ? 1779 VAL A HG12 1 
ATOM   5078 H  HG13 . VAL A 1 320 ? -24.26275 -18.92041 -28.91891 1.000 19.34093 ? 1779 VAL A HG13 1 
ATOM   5079 H  HG21 . VAL A 1 320 ? -23.86266 -21.91920 -28.95472 1.000 18.87350 ? 1779 VAL A HG21 1 
ATOM   5080 H  HG22 . VAL A 1 320 ? -24.89213 -21.17799 -29.91092 1.000 18.87350 ? 1779 VAL A HG22 1 
ATOM   5081 H  HG23 . VAL A 1 320 ? -23.75560 -22.09959 -30.52936 1.000 18.87350 ? 1779 VAL A HG23 1 
ATOM   5082 N  N    . LYS A 1 321 ? -21.17013 -20.51149 -32.31593 1.000 16.24144 ? 1780 LYS A N    1 
ATOM   5083 C  CA   . LYS A 1 321 ? -20.41055 -21.30197 -33.26696 1.000 17.65214 ? 1780 LYS A CA   1 
ATOM   5084 C  C    . LYS A 1 321 ? -19.29941 -21.95210 -32.46998 1.000 17.69688 ? 1780 LYS A C    1 
ATOM   5085 O  O    . LYS A 1 321 ? -18.45421 -21.25214 -31.89693 1.000 17.86795 ? 1780 LYS A O    1 
ATOM   5086 C  CB   . LYS A 1 321 ? -19.83060 -20.43481 -34.37807 1.000 20.46826 ? 1780 LYS A CB   1 
ATOM   5087 C  CG   . LYS A 1 321 ? -19.20308 -21.24084 -35.51475 1.000 23.57127 ? 1780 LYS A CG   1 
ATOM   5088 C  CD   . LYS A 1 321 ? -18.79716 -20.32578 -36.65362 1.000 27.00062 ? 1780 LYS A CD   1 
ATOM   5089 C  CE   . LYS A 1 321 ? -17.53951 -20.80191 -37.35430 1.000 29.77990 ? 1780 LYS A CE   1 
ATOM   5090 N  NZ   . LYS A 1 321 ? -17.11019 -19.82165 -38.38910 1.000 31.31956 ? 1780 LYS A NZ   1 
ATOM   5091 H  H    . LYS A 1 321 ? -20.68472 -20.09362 -31.74204 1.000 19.49253 ? 1780 LYS A H    1 
ATOM   5092 H  HA   . LYS A 1 321 ? -20.96952 -21.97530 -33.68540 1.000 21.18536 ? 1780 LYS A HA   1 
ATOM   5093 H  HB2  . LYS A 1 321 ? -20.54118 -19.89269 -34.75503 1.000 24.56471 ? 1780 LYS A HB2  1 
ATOM   5094 H  HB3  . LYS A 1 321 ? -19.14177 -19.86441 -34.00252 1.000 24.56471 ? 1780 LYS A HB3  1 
ATOM   5095 H  HG2  . LYS A 1 321 ? -18.41247 -21.69956 -35.19008 1.000 28.28832 ? 1780 LYS A HG2  1 
ATOM   5096 H  HG3  . LYS A 1 321 ? -19.84615 -21.88499 -35.85007 1.000 28.28832 ? 1780 LYS A HG3  1 
ATOM   5097 H  HD2  . LYS A 1 321 ? -19.51304 -20.29461 -37.30741 1.000 32.40355 ? 1780 LYS A HD2  1 
ATOM   5098 H  HD3  . LYS A 1 321 ? -18.62892 -19.43705 -36.30325 1.000 32.40355 ? 1780 LYS A HD3  1 
ATOM   5099 H  HE2  . LYS A 1 321 ? -16.82442 -20.89917 -36.70616 1.000 35.73868 ? 1780 LYS A HE2  1 
ATOM   5100 H  HE3  . LYS A 1 321 ? -17.71219 -21.65226 -37.78788 1.000 35.73868 ? 1780 LYS A HE3  1 
ATOM   5101 H  HZ1  . LYS A 1 321 ? -16.37201 -20.11014 -38.79402 1.000 37.58627 ? 1780 LYS A HZ1  1 
ATOM   5102 H  HZ2  . LYS A 1 321 ? -17.75219 -19.71999 -38.99705 1.000 37.58627 ? 1780 LYS A HZ2  1 
ATOM   5103 H  HZ3  . LYS A 1 321 ? -16.94300 -19.03349 -38.01101 1.000 37.58627 ? 1780 LYS A HZ3  1 
ATOM   5104 N  N    . GLY A 1 322 ? -19.30101 -23.27685 -32.43680 1.000 17.81268 ? 1781 GLY A N    1 
ATOM   5105 C  CA   . GLY A 1 322 ? -18.40697 -24.04129 -31.56206 1.000 17.74425 ? 1781 GLY A CA   1 
ATOM   5106 C  C    . GLY A 1 322 ? -19.20854 -24.92721 -30.62808 1.000 16.46778 ? 1781 GLY A C    1 
ATOM   5107 O  O    . GLY A 1 322 ? -20.17696 -24.51050 -29.99652 1.000 16.96258 ? 1781 GLY A O    1 
ATOM   5108 H  H    . GLY A 1 322 ? -19.81623 -23.77094 -32.91641 1.000 21.37802 ? 1781 GLY A H    1 
ATOM   5109 H  HA2  . GLY A 1 322 ? -17.82110 -24.59926 -32.09716 1.000 21.29590 ? 1781 GLY A HA2  1 
ATOM   5110 H  HA3  . GLY A 1 322 ? -17.86735 -23.43423 -31.03178 1.000 21.29590 ? 1781 GLY A HA3  1 
ATOM   5111 N  N    . THR A 1 323 ? -18.77506 -26.17929 -30.52968 1.000 15.18605 ? 1782 THR A N    1 
ATOM   5112 C  CA   A THR A 1 323 ? -19.44404 -27.10781 -29.64844 0.692 15.81507 ? 1782 THR A CA   1 
ATOM   5113 C  CA   B THR A 1 323 ? -19.48323 -27.22279 -29.79774 0.308 14.88602 ? 1782 THR A CA   1 
ATOM   5114 C  C    . THR A 1 323 ? -18.46846 -28.16447 -29.16370 1.000 14.86759 ? 1782 THR A C    1 
ATOM   5115 O  O    . THR A 1 323 ? -17.45730 -28.47968 -29.80394 1.000 15.02550 ? 1782 THR A O    1 
ATOM   5116 C  CB   A THR A 1 323 ? -20.67418 -27.74257 -30.29884 0.692 17.43895 ? 1782 THR A CB   1 
ATOM   5117 C  CB   B THR A 1 323 ? -20.33007 -28.04644 -30.78458 0.308 14.92813 ? 1782 THR A CB   1 
ATOM   5118 O  OG1  A THR A 1 323 ? -21.51957 -28.27870 -29.27086 0.692 19.29444 ? 1782 THR A OG1  1 
ATOM   5119 O  OG1  B THR A 1 323 ? -21.13527 -27.16862 -31.58151 0.308 15.36239 ? 1782 THR A OG1  1 
ATOM   5120 C  CG2  A THR A 1 323 ? -20.25319 -28.83004 -31.26630 0.692 16.93100 ? 1782 THR A CG2  1 
ATOM   5121 C  CG2  B THR A 1 323 ? -21.21451 -29.05017 -30.06316 0.308 14.67020 ? 1782 THR A CG2  1 
ATOM   5122 H  H    A THR A 1 323 ? -18.10466 -26.50395 -30.95954 0.692 18.22606 ? 1782 THR A H    1 
ATOM   5123 H  H    B THR A 1 323 ? -18.04687 -26.45977 -30.89117 0.308 18.22606 ? 1782 THR A H    1 
ATOM   5124 H  HA   A THR A 1 323 ? -19.74857 -26.62502 -28.86417 0.692 18.98089 ? 1782 THR A HA   1 
ATOM   5125 H  HA   B THR A 1 323 ? -20.03183 -26.82807 -29.10194 0.308 17.86602 ? 1782 THR A HA   1 
ATOM   5126 H  HB   A THR A 1 323 ? -21.17287 -27.08097 -30.80330 0.692 20.92954 ? 1782 THR A HB   1 
ATOM   5127 H  HB   B THR A 1 323 ? -19.73587 -28.55047 -31.36232 0.308 17.91655 ? 1782 THR A HB   1 
ATOM   5128 H  HG1  A THR A 1 323 ? -22.20068 -28.63103 -29.61373 0.692 23.15612 ? 1782 THR A HG1  1 
ATOM   5129 H  HG1  B THR A 1 323 ? -21.65619 -26.73051 -31.08927 0.308 18.43766 ? 1782 THR A HG1  1 
ATOM   5130 H  HG21 A THR A 1 323 ? -20.97656 -29.02387 -31.88279 0.692 20.31999 ? 1782 THR A HG21 1 
ATOM   5131 H  HG21 B THR A 1 323 ? -21.81061 -29.48156 -30.69519 0.308 17.60704 ? 1782 THR A HG21 1 
ATOM   5132 H  HG22 A THR A 1 323 ? -19.47723 -28.54195 -31.77206 0.692 20.31999 ? 1782 THR A HG22 1 
ATOM   5133 H  HG22 B THR A 1 323 ? -20.66725 -29.72664 -29.63445 0.308 17.60704 ? 1782 THR A HG22 1 
ATOM   5134 H  HG23 A THR A 1 323 ? -20.02924 -29.63863 -30.77955 0.692 20.31999 ? 1782 THR A HG23 1 
ATOM   5135 H  HG23 B THR A 1 323 ? -21.74483 -28.59957 -29.38742 0.308 17.60704 ? 1782 THR A HG23 1 
ATOM   5136 N  N    . VAL A 1 324 ? -18.75605 -28.64516 -27.96025 1.000 14.78074 ? 1783 VAL A N    1 
ATOM   5137 C  CA   . VAL A 1 324 ? -17.97476 -29.71505 -27.34736 1.000 15.26501 ? 1783 VAL A CA   1 
ATOM   5138 C  C    . VAL A 1 324 ? -18.43046 -31.03903 -27.94185 1.000 15.33081 ? 1783 VAL A C    1 
ATOM   5139 O  O    . VAL A 1 324 ? -19.61274 -31.39535 -27.85404 1.000 15.55452 ? 1783 VAL A O    1 
ATOM   5140 C  CB   . VAL A 1 324 ? -18.16668 -29.71417 -25.82744 1.000 16.15722 ? 1783 VAL A CB   1 
ATOM   5141 C  CG1  . VAL A 1 324 ? -17.50460 -30.88206 -25.18734 1.000 16.24934 ? 1783 VAL A CG1  1 
ATOM   5142 C  CG2  . VAL A 1 324 ? -17.64539 -28.41913 -25.25215 1.000 16.46515 ? 1783 VAL A CG2  1 
ATOM   5143 H  H    . VAL A 1 324 ? -19.40624 -28.36606 -27.47142 1.000 17.73969 ? 1783 VAL A H    1 
ATOM   5144 H  HA   . VAL A 1 324 ? -17.03400 -29.58949 -27.54765 1.000 18.32081 ? 1783 VAL A HA   1 
ATOM   5145 H  HB   . VAL A 1 324 ? -19.11421 -29.78847 -25.63360 1.000 19.39146 ? 1783 VAL A HB   1 
ATOM   5146 H  HG11 . VAL A 1 324 ? -17.44525 -30.72680 -24.23169 1.000 19.50200 ? 1783 VAL A HG11 1 
ATOM   5147 H  HG12 . VAL A 1 324 ? -18.03115 -31.67796 -25.36109 1.000 19.50200 ? 1783 VAL A HG12 1 
ATOM   5148 H  HG13 . VAL A 1 324 ? -16.61565 -30.98535 -25.56151 1.000 19.50200 ? 1783 VAL A HG13 1 
ATOM   5149 H  HG21 . VAL A 1 324 ? -17.74589 -28.43897 -24.28758 1.000 19.76098 ? 1783 VAL A HG21 1 
ATOM   5150 H  HG22 . VAL A 1 324 ? -16.70858 -28.32448 -25.48524 1.000 19.76098 ? 1783 VAL A HG22 1 
ATOM   5151 H  HG23 . VAL A 1 324 ? -18.15462 -27.68136 -25.62267 1.000 19.76098 ? 1783 VAL A HG23 1 
ATOM   5152 N  N    . ARG A 1 325 ? -17.49549 -31.78005 -28.53646 1.000 15.09657 ? 1784 ARG A N    1 
ATOM   5153 C  CA   . ARG A 1 325 ? -17.77743 -33.09234 -29.10562 1.000 15.48082 ? 1784 ARG A CA   1 
ATOM   5154 C  C    . ARG A 1 325 ? -17.41356 -34.23726 -28.17464 1.000 15.25711 ? 1784 ARG A C    1 
ATOM   5155 O  O    . ARG A 1 325 ? -18.17873 -35.20521 -28.06568 1.000 16.25197 ? 1784 ARG A O    1 
ATOM   5156 C  CB   . ARG A 1 325 ? -17.01854 -33.27403 -30.42371 1.000 16.84414 ? 1784 ARG A CB   1 
ATOM   5157 C  CG   . ARG A 1 325 ? -17.33052 -32.27876 -31.51829 1.000 18.04955 ? 1784 ARG A CG   1 
ATOM   5158 C  CD   . ARG A 1 325 ? -18.74875 -32.28359 -31.93297 1.000 19.29181 ? 1784 ARG A CD   1 
ATOM   5159 N  NE   . ARG A 1 325 ? -19.18283 -33.59334 -32.38994 1.000 20.66829 ? 1784 ARG A NE   1 
ATOM   5160 C  CZ   . ARG A 1 325 ? -18.98803 -34.06804 -33.60838 1.000 22.25532 ? 1784 ARG A CZ   1 
ATOM   5161 N  NH1  . ARG A 1 325 ? -18.28938 -33.39275 -34.50798 1.000 22.65537 ? 1784 ARG A NH1  1 
ATOM   5162 N  NH2  . ARG A 1 325 ? -19.50063 -35.26006 -33.92811 1.000 23.53968 ? 1784 ARG A NH2  1 
ATOM   5163 H  H    . ARG A 1 325 ? -16.67503 -31.53723 -28.62299 1.000 18.11868 ? 1784 ARG A H    1 
ATOM   5164 H  HA   . ARG A 1 325 ? -18.72805 -33.14424 -29.29142 1.000 18.57979 ? 1784 ARG A HA   1 
ATOM   5165 H  HB2  . ARG A 1 325 ? -16.06908 -33.20508 -30.23751 1.000 20.21577 ? 1784 ARG A HB2  1 
ATOM   5166 H  HB3  . ARG A 1 325 ? -17.22515 -34.15541 -30.77211 1.000 20.21577 ? 1784 ARG A HB3  1 
ATOM   5167 H  HG2  . ARG A 1 325 ? -17.11755 -31.38708 -31.20134 1.000 21.66226 ? 1784 ARG A HG2  1 
ATOM   5168 H  HG3  . ARG A 1 325 ? -16.79327 -32.49100 -32.29753 1.000 21.66226 ? 1784 ARG A HG3  1 
ATOM   5169 H  HD2  . ARG A 1 325 ? -19.30205 -32.02826 -31.17827 1.000 23.15297 ? 1784 ARG A HD2  1 
ATOM   5170 H  HD3  . ARG A 1 325 ? -18.86977 -31.65418 -32.66105 1.000 23.15297 ? 1784 ARG A HD3  1 
ATOM   5171 H  HE   . ARG A 1 325 ? -19.59607 -34.09559 -31.82729 1.000 24.80474 ? 1784 ARG A HE   1 
ATOM   5172 H  HH11 . ARG A 1 325 ? -18.17367 -33.71839 -35.29549 1.000 27.18924 ? 1784 ARG A HH11 1 
ATOM   5173 H  HH12 . ARG A 1 325 ? -17.95135 -32.62854 -34.30473 1.000 27.18924 ? 1784 ARG A HH12 1 
ATOM   5174 H  HH21 . ARG A 1 325 ? -19.94911 -35.70565 -33.34509 1.000 28.25042 ? 1784 ARG A HH21 1 
ATOM   5175 H  HH22 . ARG A 1 325 ? -19.38203 -35.58156 -34.71689 1.000 28.25042 ? 1784 ARG A HH22 1 
ATOM   5176 N  N    . ARG A 1 326 ? -16.25573 -34.17918 -27.52107 1.000 14.65967 ? 1785 ARG A N    1 
ATOM   5177 C  CA   . ARG A 1 326 ? -15.80118 -35.29339 -26.70465 1.000 14.76762 ? 1785 ARG A CA   1 
ATOM   5178 C  C    . ARG A 1 326 ? -14.94639 -34.75803 -25.57388 1.000 14.35700 ? 1785 ARG A C    1 
ATOM   5179 O  O    . ARG A 1 326 ? -14.17697 -33.80742 -25.75911 1.000 14.81495 ? 1785 ARG A O    1 
ATOM   5180 C  CB   . ARG A 1 326 ? -14.98836 -36.28700 -27.54924 1.000 30.02990 ? 1785 ARG A CB   1 
ATOM   5181 H  H    . ARG A 1 326 ? -15.71984 -33.50673 -27.53644 1.000 17.59441 ? 1785 ARG A H    1 
ATOM   5182 H  HA   . ARG A 1 326 ? -16.56227 -35.75485 -26.31904 1.000 17.72394 ? 1785 ARG A HA   1 
ATOM   5183 N  N    . VAL A 1 327 ? -15.07384 -35.37601 -24.40883 1.000 13.59112 ? 1786 VAL A N    1 
ATOM   5184 C  CA   . VAL A 1 327 ? -14.23648 -35.08143 -23.26391 1.000 12.83577 ? 1786 VAL A CA   1 
ATOM   5185 C  C    . VAL A 1 327 ? -13.67826 -36.39853 -22.75567 1.000 12.86209 ? 1786 VAL A C    1 
ATOM   5186 O  O    . VAL A 1 327 ? -14.43064 -37.35306 -22.55785 1.000 14.34648 ? 1786 VAL A O    1 
ATOM   5187 C  CB   . VAL A 1 327 ? -15.02434 -34.40239 -22.13475 1.000 13.31477 ? 1786 VAL A CB   1 
ATOM   5188 C  CG1  . VAL A 1 327 ? -14.12152 -34.16371 -20.93590 1.000 13.18844 ? 1786 VAL A CG1  1 
ATOM   5189 C  CG2  . VAL A 1 327 ? -15.64479 -33.12006 -22.62699 1.000 13.64113 ? 1786 VAL A CG2  1 
ATOM   5190 H  H    . VAL A 1 327 ? -15.65768 -35.98860 -24.25562 1.000 16.31215 ? 1786 VAL A H    1 
ATOM   5191 H  HA   . VAL A 1 327 ? -13.51307 -34.49668 -23.53893 1.000 15.40572 ? 1786 VAL A HA   1 
ATOM   5192 H  HB   . VAL A 1 327 ? -15.74618 -34.98319 -21.84749 1.000 15.98053 ? 1786 VAL A HB   1 
ATOM   5193 H  HG11 . VAL A 1 327 ? -14.58124 -33.58928 -20.30376 1.000 15.82893 ? 1786 VAL A HG11 1 
ATOM   5194 H  HG12 . VAL A 1 327 ? -13.91670 -35.01584 -20.52018 1.000 15.82893 ? 1786 VAL A HG12 1 
ATOM   5195 H  HG13 . VAL A 1 327 ? -13.30376 -33.73719 -21.23634 1.000 15.82893 ? 1786 VAL A HG13 1 
ATOM   5196 H  HG21 . VAL A 1 327 ? -16.09623 -32.68353 -21.88771 1.000 16.37215 ? 1786 VAL A HG21 1 
ATOM   5197 H  HG22 . VAL A 1 327 ? -14.94589 -32.54406 -22.97434 1.000 16.37215 ? 1786 VAL A HG22 1 
ATOM   5198 H  HG23 . VAL A 1 327 ? -16.28226 -33.32655 -23.32834 1.000 16.37215 ? 1786 VAL A HG23 1 
ATOM   5199 N  N    . VAL A 1 328 ? -12.36353 -36.44397 -22.54373 1.000 12.88315 ? 1787 VAL A N    1 
ATOM   5200 C  CA   . VAL A 1 328 ? -11.67825 -37.56361 -21.90726 1.000 13.85694 ? 1787 VAL A CA   1 
ATOM   5201 C  C    . VAL A 1 328 ? -11.16655 -37.06062 -20.56944 1.000 13.11738 ? 1787 VAL A C    1 
ATOM   5202 O  O    . VAL A 1 328 ? -10.49155 -36.02581 -20.51284 1.000 13.08054 ? 1787 VAL A O    1 
ATOM   5203 C  CB   . VAL A 1 328 ? -10.52491 -38.06331 -22.79175 1.000 14.60967 ? 1787 VAL A CB   1 
ATOM   5204 C  CG1  . VAL A 1 328 ? -9.63042  -39.06207 -22.04657 1.000 15.31764 ? 1787 VAL A CG1  1 
ATOM   5205 C  CG2  . VAL A 1 328 ? -11.11039 -38.63802 -24.05493 1.000 14.92286 ? 1787 VAL A CG2  1 
ATOM   5206 H  H    . VAL A 1 328 ? -11.82736 -35.81081 -22.77007 1.000 15.46257 ? 1787 VAL A H    1 
ATOM   5207 H  HA   . VAL A 1 328 ? -12.28720 -38.30305 -21.75457 1.000 16.63113 ? 1787 VAL A HA   1 
ATOM   5208 H  HB   . VAL A 1 328 ? -9.93925  -37.32712 -23.02823 1.000 17.53440 ? 1787 VAL A HB   1 
ATOM   5209 H  HG11 . VAL A 1 328 ? -9.04468  -39.49862 -22.68471 1.000 18.38397 ? 1787 VAL A HG11 1 
ATOM   5210 H  HG12 . VAL A 1 328 ? -9.10356  -38.58353 -21.38754 1.000 18.38397 ? 1787 VAL A HG12 1 
ATOM   5211 H  HG13 . VAL A 1 328 ? -10.19056 -39.72094 -21.60720 1.000 18.38397 ? 1787 VAL A HG13 1 
ATOM   5212 H  HG21 . VAL A 1 328 ? -10.39304 -38.99528 -24.60143 1.000 17.91023 ? 1787 VAL A HG21 1 
ATOM   5213 H  HG22 . VAL A 1 328 ? -11.73208 -39.34510 -23.82163 1.000 17.91023 ? 1787 VAL A HG22 1 
ATOM   5214 H  HG23 . VAL A 1 328 ? -11.57431 -37.93516 -24.53624 1.000 17.91023 ? 1787 VAL A HG23 1 
ATOM   5215 N  N    . LEU A 1 329 ? -11.49230 -37.76815 -19.49322 1.000 13.05685 ? 1788 LEU A N    1 
ATOM   5216 C  CA   . LEU A 1 329 ? -11.06531 -37.39273 -18.15541 1.000 12.59890 ? 1788 LEU A CA   1 
ATOM   5217 C  C    . LEU A 1 329 ? -10.27698 -38.54631 -17.54611 1.000 12.73576 ? 1788 LEU A C    1 
ATOM   5218 O  O    . LEU A 1 329 ? -10.83186 -39.63375 -17.32400 1.000 13.10422 ? 1788 LEU A O    1 
ATOM   5219 C  CB   . LEU A 1 329 ? -12.24551 -37.00691 -17.27093 1.000 12.77260 ? 1788 LEU A CB   1 
ATOM   5220 C  CG   . LEU A 1 329 ? -11.88663 -36.72429 -15.81868 1.000 12.90157 ? 1788 LEU A CG   1 
ATOM   5221 C  CD1  . LEU A 1 329 ? -10.84189 -35.61277 -15.67157 1.000 13.16476 ? 1788 LEU A CD1  1 
ATOM   5222 C  CD2  . LEU A 1 329 ? -13.16239 -36.33512 -15.05706 1.000 13.48848 ? 1788 LEU A CD2  1 
ATOM   5223 H  H    . LEU A 1 329 ? -11.96943 -38.48329 -19.51595 1.000 15.67101 ? 1788 LEU A H    1 
ATOM   5224 H  HA   . LEU A 1 329 ? -10.47920 -36.62212 -18.21481 1.000 15.12148 ? 1788 LEU A HA   1 
ATOM   5225 H  HB2  . LEU A 1 329 ? -12.65205 -36.20432 -17.63354 1.000 15.32992 ? 1788 LEU A HB2  1 
ATOM   5226 H  HB3  . LEU A 1 329 ? -12.88596 -37.73538 -17.27778 1.000 15.32992 ? 1788 LEU A HB3  1 
ATOM   5227 H  HG   . LEU A 1 329 ? -11.49392 -37.52702 -15.44145 1.000 15.48468 ? 1788 LEU A HG   1 
ATOM   5228 H  HD11 . LEU A 1 329 ? -10.72964 -35.40744 -14.73022 1.000 15.80050 ? 1788 LEU A HD11 1 
ATOM   5229 H  HD12 . LEU A 1 329 ? -10.00087 -35.91828 -16.04606 1.000 15.80050 ? 1788 LEU A HD12 1 
ATOM   5230 H  HD13 . LEU A 1 329 ? -11.14930 -34.82543 -16.14749 1.000 15.80050 ? 1788 LEU A HD13 1 
ATOM   5231 H  HD21 . LEU A 1 329 ? -12.93352 -36.14542 -14.13373 1.000 16.18897 ? 1788 LEU A HD21 1 
ATOM   5232 H  HD22 . LEU A 1 329 ? -13.54915 -35.54748 -15.47051 1.000 16.18897 ? 1788 LEU A HD22 1 
ATOM   5233 H  HD23 . LEU A 1 329 ? -13.79144 -37.07241 -15.09715 1.000 16.18897 ? 1788 LEU A HD23 1 
ATOM   5234 N  N    . ARG A 1 330 ? -8.99540  -38.31575 -17.27596 1.000 13.02527 ? 1789 ARG A N    1 
ATOM   5235 C  CA   . ARG A 1 330 ? -8.12987  -39.32223 -16.66636 1.000 13.50427 ? 1789 ARG A CA   1 
ATOM   5236 C  C    . ARG A 1 330 ? -8.25528  -40.67193 -17.38017 1.000 13.77799 ? 1789 ARG A C    1 
ATOM   5237 O  O    . ARG A 1 330 ? -8.40533  -41.73554 -16.76092 1.000 14.87812 ? 1789 ARG A O    1 
ATOM   5238 C  CB   . ARG A 1 330 ? -8.34602  -39.42079 -15.15269 1.000 13.10159 ? 1789 ARG A CB   1 
ATOM   5239 C  CG   . ARG A 1 330 ? -7.81547  -38.17871 -14.41528 1.000 13.40426 ? 1789 ARG A CG   1 
ATOM   5240 C  CD   . ARG A 1 330 ? -7.99349  -38.22642 -12.92686 1.000 13.46742 ? 1789 ARG A CD   1 
ATOM   5241 N  NE   . ARG A 1 330 ? -9.37273  -37.98739 -12.52132 1.000 13.76746 ? 1789 ARG A NE   1 
ATOM   5242 C  CZ   . ARG A 1 330 ? -10.24924 -38.93698 -12.20933 1.000 13.81483 ? 1789 ARG A CZ   1 
ATOM   5243 N  NH1  . ARG A 1 330 ? -9.95389  -40.22060 -12.31713 1.000 13.65166 ? 1789 ARG A NH1  1 
ATOM   5244 N  NH2  . ARG A 1 330 ? -11.45141 -38.58792 -11.76848 1.000 14.28594 ? 1789 ARG A NH2  1 
ATOM   5245 H  H    . ARG A 1 330 ? -8.59665  -37.57145 -17.43909 1.000 15.63312 ? 1789 ARG A H    1 
ATOM   5246 H  HA   . ARG A 1 330 ? -7.20938  -39.03998 -16.78446 1.000 16.20792 ? 1789 ARG A HA   1 
ATOM   5247 H  HB2  . ARG A 1 330 ? -9.29546  -39.50006 -14.97055 1.000 15.72471 ? 1789 ARG A HB2  1 
ATOM   5248 H  HB3  . ARG A 1 330 ? -7.87701  -40.19918 -14.81351 1.000 15.72471 ? 1789 ARG A HB3  1 
ATOM   5249 H  HG2  . ARG A 1 330 ? -6.86617  -38.09209 -14.59482 1.000 16.08791 ? 1789 ARG A HG2  1 
ATOM   5250 H  HG3  . ARG A 1 330 ? -8.28768  -37.39718 -14.74256 1.000 16.08791 ? 1789 ARG A HG3  1 
ATOM   5251 H  HD2  . ARG A 1 330 ? -7.73288  -39.10330 -12.60424 1.000 16.16371 ? 1789 ARG A HD2  1 
ATOM   5252 H  HD3  . ARG A 1 330 ? -7.43759  -37.54415 -12.51895 1.000 16.16371 ? 1789 ARG A HD3  1 
ATOM   5253 H  HE   . ARG A 1 330 ? -9.63962  -37.17085 -12.48080 1.000 16.52375 ? 1789 ARG A HE   1 
ATOM   5254 H  HH11 . ARG A 1 330 ? -9.17657  -40.46106 -12.59561 1.000 16.38479 ? 1789 ARG A HH11 1 
ATOM   5255 H  HH12 . ARG A 1 330 ? -10.53900 -40.81544 -12.10879 1.000 16.38479 ? 1789 ARG A HH12 1 
ATOM   5256 H  HH21 . ARG A 1 330 ? -11.65505 -37.75629 -11.68775 1.000 17.14593 ? 1789 ARG A HH21 1 
ATOM   5257 H  HH22 . ARG A 1 330 ? -12.02677 -39.19337 -11.56354 1.000 17.14593 ? 1789 ARG A HH22 1 
ATOM   5258 N  N    . GLY A 1 331 ? -8.21623  -40.60803 -18.71089 1.000 13.91222 ? 1790 GLY A N    1 
ATOM   5259 C  CA   . GLY A 1 331 ? -8.14166  -41.78494 -19.55017 1.000 15.21763 ? 1790 GLY A CA   1 
ATOM   5260 C  C    . GLY A 1 331 ? -9.45621  -42.44514 -19.89634 1.000 16.31513 ? 1790 GLY A C    1 
ATOM   5261 O  O    . GLY A 1 331 ? -9.44751  -43.46375 -20.60858 1.000 18.49434 ? 1790 GLY A O    1 
ATOM   5262 H  H    . GLY A 1 331 ? -8.23249  -39.87216 -19.15567 1.000 16.69746 ? 1790 GLY A H    1 
ATOM   5263 H  HA2  . GLY A 1 331 ? -7.71328  -41.53760 -20.38456 1.000 18.26396 ? 1790 GLY A HA2  1 
ATOM   5264 H  HA3  . GLY A 1 331 ? -7.59514  -42.44707 -19.09873 1.000 18.26396 ? 1790 GLY A HA3  1 
ATOM   5265 N  N    . GLU A 1 332 ? -10.58204 -41.92463 -19.41178 1.000 15.42819 ? 1791 GLU A N    1 
ATOM   5266 C  CA   . GLU A 1 332 ? -11.89364 -42.48982 -19.70544 1.000 15.87561 ? 1791 GLU A CA   1 
ATOM   5267 C  C    . GLU A 1 332 ? -12.71055 -41.48425 -20.50528 1.000 15.55452 ? 1791 GLU A C    1 
ATOM   5268 O  O    . GLU A 1 332 ? -12.66115 -40.27735 -20.23925 1.000 14.95445 ? 1791 GLU A O    1 
ATOM   5269 C  CB   . GLU A 1 332 ? -12.64472 -42.82554 -18.41133 1.000 17.51528 ? 1791 GLU A CB   1 
ATOM   5270 C  CG   . GLU A 1 332 ? -11.99467 -43.93657 -17.55090 1.000 19.58132 ? 1791 GLU A CG   1 
ATOM   5271 C  CD   . GLU A 1 332 ? -11.71123 -45.22336 -18.28886 1.000 23.04225 ? 1791 GLU A CD   1 
ATOM   5272 O  OE1  . GLU A 1 332 ? -12.53552 -45.61831 -19.14002 1.000 24.79509 ? 1791 GLU A OE1  1 
ATOM   5273 O  OE2  . GLU A 1 332 ? -10.62558 -45.81353 -18.05554 1.000 24.12660 ? 1791 GLU A OE2  1 
ATOM   5274 H  H    . GLU A 1 332 ? -10.60997 -41.23243 -18.90219 1.000 18.51662 ? 1791 GLU A H    1 
ATOM   5275 H  HA   . GLU A 1 332 ? -11.78888 -43.30129 -20.22645 1.000 19.05353 ? 1791 GLU A HA   1 
ATOM   5276 H  HB2  . GLU A 1 332 ? -12.69136 -42.02455 -17.86623 1.000 21.02113 ? 1791 GLU A HB2  1 
ATOM   5277 H  HB3  . GLU A 1 332 ? -13.53889 -43.12185 -18.64278 1.000 21.02113 ? 1791 GLU A HB3  1 
ATOM   5278 H  HG2  . GLU A 1 332 ? -11.15018 -43.60582 -17.20687 1.000 23.50038 ? 1791 GLU A HG2  1 
ATOM   5279 H  HG3  . GLU A 1 332 ? -12.59234 -44.14733 -16.81655 1.000 23.50038 ? 1791 GLU A HG3  1 
ATOM   5280 N  N    . VAL A 1 333 ? -13.46216 -41.96875 -21.48780 1.000 15.87561 ? 1792 VAL A N    1 
ATOM   5281 C  CA   . VAL A 1 333 ? -14.39790 -41.10882 -22.20083 1.000 15.93877 ? 1792 VAL A CA   1 
ATOM   5282 C  C    . VAL A 1 333 ? -15.48106 -40.66212 -21.23063 1.000 14.85180 ? 1792 VAL A C    1 
ATOM   5283 O  O    . VAL A 1 333 ? -16.21830 -41.48050 -20.66401 1.000 15.73875 ? 1792 VAL A O    1 
ATOM   5284 C  CB   . VAL A 1 333 ? -14.98841 -41.83326 -23.41441 1.000 17.69425 ? 1792 VAL A CB   1 
ATOM   5285 C  CG1  . VAL A 1 333 ? -15.94978 -40.91390 -24.13532 1.000 18.38643 ? 1792 VAL A CG1  1 
ATOM   5286 C  CG2  . VAL A 1 333 ? -13.88771 -42.29491 -24.35735 1.000 18.61278 ? 1792 VAL A CG2  1 
ATOM   5287 H  H    . VAL A 1 333 ? -13.44915 -42.78499 -21.75835 1.000 19.05353 ? 1792 VAL A H    1 
ATOM   5288 H  HA   . VAL A 1 333 ? -13.93349 -40.31982 -22.52129 1.000 19.12933 ? 1792 VAL A HA   1 
ATOM   5289 H  HB   . VAL A 1 333 ? -15.46884 -42.62024 -23.11316 1.000 21.23589 ? 1792 VAL A HB   1 
ATOM   5290 H  HG11 . VAL A 1 333 ? -16.19532 -41.31587 -24.98327 1.000 22.06652 ? 1792 VAL A HG11 1 
ATOM   5291 H  HG12 . VAL A 1 333 ? -16.74009 -40.79036 -23.58664 1.000 22.06652 ? 1792 VAL A HG12 1 
ATOM   5292 H  HG13 . VAL A 1 333 ? -15.51590 -40.05979 -24.28746 1.000 22.06652 ? 1792 VAL A HG13 1 
ATOM   5293 H  HG21 . VAL A 1 333 ? -14.29200 -42.66085 -25.15956 1.000 22.33813 ? 1792 VAL A HG21 1 
ATOM   5294 H  HG22 . VAL A 1 333 ? -13.32839 -41.53595 -24.58547 1.000 22.33813 ? 1792 VAL A HG22 1 
ATOM   5295 H  HG23 . VAL A 1 333 ? -13.35719 -42.97547 -23.91431 1.000 22.33813 ? 1792 VAL A HG23 1 
ATOM   5296 N  N    . ALA A 1 334 ? -15.57510 -39.35128 -21.02760 1.000 14.17014 ? 1793 ALA A N    1 
ATOM   5297 C  CA   . ALA A 1 334 ? -16.50585 -38.79303 -20.06630 1.000 13.64903 ? 1793 ALA A CA   1 
ATOM   5298 C  C    . ALA A 1 334 ? -17.74262 -38.21159 -20.72280 1.000 13.72272 ? 1793 ALA A C    1 
ATOM   5299 O  O    . ALA A 1 334 ? -18.79978 -38.15964 -20.08710 1.000 14.35437 ? 1793 ALA A O    1 
ATOM   5300 C  CB   . ALA A 1 334 ? -15.81686 -37.69350 -19.25834 1.000 13.90169 ? 1793 ALA A CB   1 
ATOM   5301 H  H    . ALA A 1 334 ? -15.10371 -38.76256 -21.44088 1.000 17.00697 ? 1793 ALA A H    1 
ATOM   5302 H  HA   . ALA A 1 334 ? -16.78711 -39.48875 -19.45168 1.000 16.38163 ? 1793 ALA A HA   1 
ATOM   5303 H  HB1  . ALA A 1 334 ? -16.44710 -37.33165 -18.61588 1.000 16.68482 ? 1793 ALA A HB1  1 
ATOM   5304 H  HB2  . ALA A 1 334 ? -15.05363 -38.07297 -18.79533 1.000 16.68482 ? 1793 ALA A HB2  1 
ATOM   5305 H  HB3  . ALA A 1 334 ? -15.52280 -36.99439 -19.86305 1.000 16.68482 ? 1793 ALA A HB3  1 
ATOM   5306 N  N    . TYR A 1 335 ? -17.64361 -37.79845 -21.98335 1.000 14.38859 ? 1794 TYR A N    1 
ATOM   5307 C  CA   . TYR A 1 335 ? -18.74588 -37.13138 -22.66765 1.000 14.47018 ? 1794 TYR A CA   1 
ATOM   5308 C  C    . TYR A 1 335 ? -18.53866 -37.27806 -24.16421 1.000 15.34923 ? 1794 TYR A C    1 
ATOM   5309 O  O    . TYR A 1 335 ? -17.42926 -37.06243 -24.65145 1.000 14.71758 ? 1794 TYR A O    1 
ATOM   5310 C  CB   . TYR A 1 335 ? -18.77662 -35.63729 -22.28898 1.000 14.37806 ? 1794 TYR A CB   1 
ATOM   5311 C  CG   . TYR A 1 335 ? -19.81447 -34.80969 -23.02630 1.000 14.22015 ? 1794 TYR A CG   1 
ATOM   5312 C  CD1  . TYR A 1 335 ? -21.13439 -34.78236 -22.59705 1.000 14.90180 ? 1794 TYR A CD1  1 
ATOM   5313 C  CD2  . TYR A 1 335 ? -19.47894 -34.05565 -24.13152 1.000 14.35964 ? 1794 TYR A CD2  1 
ATOM   5314 C  CE1  . TYR A 1 335 ? -22.08205 -34.03536 -23.25386 1.000 14.37280 ? 1794 TYR A CE1  1 
ATOM   5315 C  CE2  . TYR A 1 335 ? -20.41976 -33.28095 -24.79745 1.000 14.95971 ? 1794 TYR A CE2  1 
ATOM   5316 C  CZ   . TYR A 1 335 ? -21.72689 -33.27909 -24.35940 1.000 15.09130 ? 1794 TYR A CZ   1 
ATOM   5317 O  OH   . TYR A 1 335 ? -22.68347 -32.51060 -25.00643 1.000 16.91784 ? 1794 TYR A OH   1 
ATOM   5318 H  H    . TYR A 1 335 ? -16.94048 -37.89392 -22.46923 1.000 17.26910 ? 1794 TYR A H    1 
ATOM   5319 H  HA   . TYR A 1 335 ? -19.59023 -37.54307 -22.42582 1.000 17.36701 ? 1794 TYR A HA   1 
ATOM   5320 H  HB2  . TYR A 1 335 ? -18.96710 -35.56476 -21.34063 1.000 17.25647 ? 1794 TYR A HB2  1 
ATOM   5321 H  HB3  . TYR A 1 335 ? -17.90721 -35.25341 -22.48304 1.000 17.25647 ? 1794 TYR A HB3  1 
ATOM   5322 H  HD1  . TYR A 1 335 ? -21.38180 -35.27910 -21.85077 1.000 17.88496 ? 1794 TYR A HD1  1 
ATOM   5323 H  HD2  . TYR A 1 335 ? -18.60107 -34.06629 -24.43831 1.000 17.23436 ? 1794 TYR A HD2  1 
ATOM   5324 H  HE1  . TYR A 1 335 ? -22.96310 -34.03724 -22.95612 1.000 17.25015 ? 1794 TYR A HE1  1 
ATOM   5325 H  HE2  . TYR A 1 335 ? -20.17028 -32.76817 -25.53211 1.000 17.95445 ? 1794 TYR A HE2  1 
ATOM   5326 H  HH   . TYR A 1 335 ? -22.33715 -32.10984 -25.65838 1.000 20.30420 ? 1794 TYR A HH   1 
ATOM   5327 N  N    A ILE A 1 336 ? -19.58827 -37.67799 -24.88747 0.756 16.17828 ? 1795 ILE A N    1 
ATOM   5328 N  N    B ILE A 1 336 ? -19.59716 -37.62637 -24.89016 0.244 16.42567 ? 1795 ILE A N    1 
ATOM   5329 C  CA   A ILE A 1 336 ? -19.58901 -37.61779 -26.34769 0.756 17.54160 ? 1795 ILE A CA   1 
ATOM   5330 C  CA   B ILE A 1 336 ? -19.54677 -37.57503 -26.34604 0.244 17.77320 ? 1795 ILE A CA   1 
ATOM   5331 C  C    A ILE A 1 336 ? -20.94323 -37.10389 -26.80313 0.756 17.04680 ? 1795 ILE A C    1 
ATOM   5332 C  C    B ILE A 1 336 ? -20.90315 -37.17350 -26.90700 0.244 17.39158 ? 1795 ILE A C    1 
ATOM   5333 O  O    A ILE A 1 336 ? -21.97619 -37.72657 -26.50963 0.756 16.79414 ? 1795 ILE A O    1 
ATOM   5334 O  O    B ILE A 1 336 ? -21.89655 -37.89447 -26.75260 0.244 17.25209 ? 1795 ILE A O    1 
ATOM   5335 C  CB   A ILE A 1 336 ? -19.36103 -38.96996 -27.03641 0.756 19.80239 ? 1795 ILE A CB   1 
ATOM   5336 C  CB   B ILE A 1 336 ? -19.04856 -38.89128 -26.97383 0.244 19.66554 ? 1795 ILE A CB   1 
ATOM   5337 C  CG1  A ILE A 1 336 ? -18.03815 -39.58354 -26.66968 0.756 20.93411 ? 1795 ILE A CG1  1 
ATOM   5338 C  CG1  B ILE A 1 336 ? -19.81942 -40.08886 -26.41643 0.244 20.64986 ? 1795 ILE A CG1  1 
ATOM   5339 C  CG2  A ILE A 1 336 ? -19.44123 -38.82226 -28.56817 0.756 20.08401 ? 1795 ILE A CG2  1 
ATOM   5340 C  CG2  B ILE A 1 336 ? -17.56316 -39.05474 -26.75150 0.244 20.39720 ? 1795 ILE A CG2  1 
ATOM   5341 C  CD1  A ILE A 1 336 ? -17.79203 -40.88916 -27.44639 0.756 21.66577 ? 1795 ILE A CD1  1 
ATOM   5342 C  CD1  B ILE A 1 336 ? -19.25725 -41.41563 -26.86857 0.244 21.75789 ? 1795 ILE A CD1  1 
ATOM   5343 H  H    A ILE A 1 336 ? -20.31543 -37.98979 -24.55040 0.756 19.41673 ? 1795 ILE A H    1 
ATOM   5344 H  H    B ILE A 1 336 ? -20.34761 -37.89288 -24.56552 0.244 19.71361 ? 1795 ILE A H    1 
ATOM   5345 H  HA   A ILE A 1 336 ? -18.87950 -37.00720 -26.60201 0.756 21.05271 ? 1795 ILE A HA   1 
ATOM   5346 H  HA   B ILE A 1 336 ? -18.90935 -36.88422 -26.58559 0.244 21.33064 ? 1795 ILE A HA   1 
ATOM   5347 H  HB   A ILE A 1 336 ? -20.06550 -39.55778 -26.72162 0.756 23.76567 ? 1795 ILE A HB   1 
ATOM   5348 H  HB   B ILE A 1 336 ? -19.21275 -38.85039 -27.92895 0.244 23.60144 ? 1795 ILE A HB   1 
ATOM   5349 H  HG12 A ILE A 1 336 ? -17.32529 -38.96124 -26.88295 0.756 25.12373 ? 1795 ILE A HG12 1 
ATOM   5350 H  HG12 B ILE A 1 336 ? -19.78307 -40.06316 -25.44745 0.244 24.78263 ? 1795 ILE A HG12 1 
ATOM   5351 H  HG13 A ILE A 1 336 ? -18.02963 -39.78529 -25.72094 0.756 25.12373 ? 1795 ILE A HG13 1 
ATOM   5352 H  HG13 B ILE A 1 336 ? -20.74075 -40.03685 -26.71535 0.244 24.78263 ? 1795 ILE A HG13 1 
ATOM   5353 H  HG21 A ILE A 1 336 ? -19.43974 -39.70465 -28.97103 0.756 24.10360 ? 1795 ILE A HG21 1 
ATOM   5354 H  HG21 B ILE A 1 336 ? -17.22931 -39.74612 -27.34433 0.244 24.47944 ? 1795 ILE A HG21 1 
ATOM   5355 H  HG22 A ILE A 1 336 ? -20.25969 -38.35511 -28.79797 0.756 24.10360 ? 1795 ILE A HG22 1 
ATOM   5356 H  HG22 B ILE A 1 336 ? -17.12070 -38.21300 -26.94277 0.244 24.47944 ? 1795 ILE A HG22 1 
ATOM   5357 H  HG23 A ILE A 1 336 ? -18.67359 -38.31622 -28.87727 0.756 24.10360 ? 1795 ILE A HG23 1 
ATOM   5358 H  HG23 B ILE A 1 336 ? -17.40801 -39.30762 -25.82798 0.244 24.47944 ? 1795 ILE A HG23 1 
ATOM   5359 H  HD11 A ILE A 1 336 ? -17.11847 -41.41052 -26.98229 0.756 26.00173 ? 1795 ILE A HD11 1 
ATOM   5360 H  HD11 B ILE A 1 336 ? -19.92434 -42.10566 -26.72801 0.244 26.11227 ? 1795 ILE A HD11 1 
ATOM   5361 H  HD12 A ILE A 1 336 ? -18.62191 -41.38902 -27.49485 0.756 26.00173 ? 1795 ILE A HD12 1 
ATOM   5362 H  HD12 B ILE A 1 336 ? -19.03323 -41.35913 -27.81066 0.244 26.11227 ? 1795 ILE A HD12 1 
ATOM   5363 H  HD13 A ILE A 1 336 ? -17.48421 -40.67167 -28.34017 0.756 26.00173 ? 1795 ILE A HD13 1 
ATOM   5364 H  HD13 B ILE A 1 336 ? -18.46152 -41.61443 -26.35070 0.244 26.11227 ? 1795 ILE A HD13 1 
ATOM   5365 N  N    . ASP A 1 337 ? -20.93000 -36.03636 -27.59492 1.000 17.47054 ? 1796 ASP A N    1 
ATOM   5366 C  CA   . ASP A 1 337 ? -22.10265 -35.56771 -28.33599 1.000 18.03113 ? 1796 ASP A CA   1 
ATOM   5367 C  C    . ASP A 1 337 ? -23.40789 -35.69734 -27.56464 1.000 18.40223 ? 1796 ASP A C    1 
ATOM   5368 O  O    . ASP A 1 337 ? -24.39798 -36.24640 -28.05934 1.000 18.22589 ? 1796 ASP A O    1 
ATOM   5369 C  CB   . ASP A 1 337 ? -22.20980 -36.31362 -29.66424 1.000 18.33380 ? 1796 ASP A CB   1 
ATOM   5370 C  CG   . ASP A 1 337 ? -21.09375 -35.95984 -30.62903 1.000 18.78385 ? 1796 ASP A CG   1 
ATOM   5371 O  OD1  . ASP A 1 337 ? -20.54163 -34.84672 -30.50821 1.000 20.43668 ? 1796 ASP A OD1  1 
ATOM   5372 O  OD2  . ASP A 1 337 ? -20.76953 -36.78257 -31.51326 1.000 18.31011 ? 1796 ASP A OD2  1 
ATOM   5373 H  H    . ASP A 1 337 ? -20.23369 -35.54894 -27.72596 1.000 20.96744 ? 1796 ASP A H    1 
ATOM   5374 H  HA   . ASP A 1 337 ? -21.97381 -34.61835 -28.48771 1.000 21.64015 ? 1796 ASP A HA   1 
ATOM   5375 H  HB2  . ASP A 1 337 ? -22.16838 -37.26783 -29.49493 1.000 22.00335 ? 1796 ASP A HB2  1 
ATOM   5376 H  HB3  . ASP A 1 337 ? -23.05354 -36.08786 -30.08617 1.000 22.00335 ? 1796 ASP A HB3  1 
ATOM   5377 N  N    . GLY A 1 338 ? -23.40071 -35.18567 -26.34284 1.000 19.73660 ? 1797 GLY A N    1 
ATOM   5378 C  CA   . GLY A 1 338 ? -24.59682 -35.08345 -25.54608 1.000 20.20770 ? 1797 GLY A CA   1 
ATOM   5379 C  C    . GLY A 1 338 ? -24.79218 -36.18990 -24.54047 1.000 20.19718 ? 1797 GLY A C    1 
ATOM   5380 O  O    . GLY A 1 338 ? -25.71850 -36.10697 -23.72927 1.000 22.99225 ? 1797 GLY A O    1 
ATOM   5381 H  H    . GLY A 1 338 ? -22.69650 -34.88608 -25.95049 1.000 23.68671 ? 1797 GLY A H    1 
ATOM   5382 H  HA2  . GLY A 1 338 ? -24.57440 -34.24417 -25.06027 1.000 24.25204 ? 1797 GLY A HA2  1 
ATOM   5383 H  HA3  . GLY A 1 338 ? -25.36467 -35.08485 -26.13878 1.000 24.25204 ? 1797 GLY A HA3  1 
ATOM   5384 N  N    . GLN A 1 339 ? -23.94192 -37.19579 -24.53714 1.000 18.98124 ? 1798 GLN A N    1 
ATOM   5385 C  CA   . GLN A 1 339 ? -24.05428 -38.31830 -23.61699 1.000 19.43656 ? 1798 GLN A CA   1 
ATOM   5386 C  C    . GLN A 1 339 ? -22.91153 -38.24210 -22.61649 1.000 18.10219 ? 1798 GLN A C    1 
ATOM   5387 O  O    . GLN A 1 339 ? -21.74359 -38.26243 -23.00464 1.000 18.27853 ? 1798 GLN A O    1 
ATOM   5388 C  CB   . GLN A 1 339 ? -23.97482 -39.63972 -24.38605 1.000 21.27626 ? 1798 GLN A CB   1 
ATOM   5389 C  CG   . GLN A 1 339 ? -23.86148 -40.84588 -23.45449 1.000 23.60022 ? 1798 GLN A CG   1 
ATOM   5390 C  CD   . GLN A 1 339 ? -25.16276 -41.37152 -22.92437 1.000 25.50308 ? 1798 GLN A CD   1 
ATOM   5391 O  OE1  . GLN A 1 339 ? -26.17329 -41.43793 -23.63249 1.000 26.15315 ? 1798 GLN A OE1  1 
ATOM   5392 N  NE2  . GLN A 1 339 ? -25.17375 -41.65256 -21.61937 1.000 26.26106 ? 1798 GLN A NE2  1 
ATOM   5393 H  H    . GLN A 1 339 ? -23.27121 -37.25627 -25.07202 1.000 22.78029 ? 1798 GLN A H    1 
ATOM   5394 H  HA   . GLN A 1 339 ? -24.89738 -38.26996 -23.13976 1.000 23.32667 ? 1798 GLN A HA   1 
ATOM   5395 H  HB2  . GLN A 1 339 ? -24.77737 -39.74477 -24.92064 1.000 25.53430 ? 1798 GLN A HB2  1 
ATOM   5396 H  HB3  . GLN A 1 339 ? -23.19312 -39.62647 -24.96022 1.000 25.53430 ? 1798 GLN A HB3  1 
ATOM   5397 H  HG2  . GLN A 1 339 ? -23.43415 -41.56872 -23.94008 1.000 28.32306 ? 1798 GLN A HG2  1 
ATOM   5398 H  HG3  . GLN A 1 339 ? -23.31933 -40.59314 -22.69089 1.000 28.32306 ? 1798 GLN A HG3  1 
ATOM   5399 H  HE21 . GLN A 1 339 ? -24.46600 -41.52850 -21.14682 1.000 31.51607 ? 1798 GLN A HE21 1 
ATOM   5400 H  HE22 . GLN A 1 339 ? -25.88857 -41.95767 -21.25122 1.000 31.51607 ? 1798 GLN A HE22 1 
ATOM   5401 N  N    . VAL A 1 340 ? -23.23428 -38.21163 -21.34588 1.000 17.79952 ? 1799 VAL A N    1 
ATOM   5402 C  CA   . VAL A 1 340 ? -22.22606 -38.34616 -20.30321 1.000 17.95744 ? 1799 VAL A CA   1 
ATOM   5403 C  C    . VAL A 1 340 ? -22.00504 -39.83433 -20.05810 1.000 18.14957 ? 1799 VAL A C    1 
ATOM   5404 O  O    . VAL A 1 340 ? -22.96547 -40.61703 -19.98228 1.000 19.29181 ? 1799 VAL A O    1 
ATOM   5405 C  CB   . VAL A 1 340 ? -22.65205 -37.59836 -19.02921 1.000 18.78648 ? 1799 VAL A CB   1 
ATOM   5406 C  CG1  . VAL A 1 340 ? -21.71080 -37.87961 -17.88709 1.000 20.00242 ? 1799 VAL A CG1  1 
ATOM   5407 C  CG2  . VAL A 1 340 ? -22.71006 -36.08754 -19.27981 1.000 19.30496 ? 1799 VAL A CG2  1 
ATOM   5408 H  H    . VAL A 1 340 ? -24.03622 -38.11345 -21.05117 1.000 21.36222 ? 1799 VAL A H    1 
ATOM   5409 H  HA   . VAL A 1 340 ? -21.38443 -37.96062 -20.59291 1.000 21.55172 ? 1799 VAL A HA   1 
ATOM   5410 H  HB   . VAL A 1 340 ? -23.53595 -37.91420 -18.78454 1.000 22.54658 ? 1799 VAL A HB   1 
ATOM   5411 H  HG11 . VAL A 1 340 ? -21.83117 -37.20123 -17.20429 1.000 24.00570 ? 1799 VAL A HG11 1 
ATOM   5412 H  HG12 . VAL A 1 340 ? -21.91045 -38.75572 -17.52175 1.000 24.00570 ? 1799 VAL A HG12 1 
ATOM   5413 H  HG13 . VAL A 1 340 ? -20.79885 -37.85876 -18.21696 1.000 24.00570 ? 1799 VAL A HG13 1 
ATOM   5414 H  HG21 . VAL A 1 340 ? -23.01877 -35.64532 -18.47356 1.000 23.16875 ? 1799 VAL A HG21 1 
ATOM   5415 H  HG22 . VAL A 1 340 ? -21.82268 -35.77153 -19.51133 1.000 23.16875 ? 1799 VAL A HG22 1 
ATOM   5416 H  HG23 . VAL A 1 340 ? -23.32458 -35.91182 -20.00945 1.000 23.16875 ? 1799 VAL A HG23 1 
ATOM   5417 N  N    . LEU A 1 341 ? -20.73613 -40.23376 -19.97532 1.000 17.96797 ? 1800 LEU A N    1 
ATOM   5418 C  CA   . LEU A 1 341 ? -20.37179 -41.64734 -19.94163 1.000 18.67595 ? 1800 LEU A CA   1 
ATOM   5419 C  C    . LEU A 1 341 ? -19.55192 -42.02102 -18.71732 1.000 18.58120 ? 1800 LEU A C    1 
ATOM   5420 O  O    . LEU A 1 341 ? -19.05622 -43.15199 -18.63882 1.000 20.91042 ? 1800 LEU A O    1 
ATOM   5421 C  CB   . LEU A 1 341 ? -19.63503 -42.05151 -21.21692 1.000 20.72882 ? 1800 LEU A CB   1 
ATOM   5422 C  CG   . LEU A 1 341 ? -20.48317 -41.98118 -22.48367 1.000 22.22374 ? 1800 LEU A CG   1 
ATOM   5423 C  CD1  . LEU A 1 341 ? -19.57563 -42.01597 -23.71207 1.000 23.45283 ? 1800 LEU A CD1  1 
ATOM   5424 C  CD2  . LEU A 1 341 ? -21.50224 -43.11159 -22.50844 1.000 23.06331 ? 1800 LEU A CD2  1 
ATOM   5425 H  H    . LEU A 1 341 ? -20.06349 -39.69926 -19.93713 1.000 21.56436 ? 1800 LEU A H    1 
ATOM   5426 H  HA   . LEU A 1 341 ? -21.19208 -42.16381 -19.90574 1.000 22.41393 ? 1800 LEU A HA   1 
ATOM   5427 H  HB2  . LEU A 1 341 ? -18.87727 -41.45798 -21.33698 1.000 24.87738 ? 1800 LEU A HB2  1 
ATOM   5428 H  HB3  . LEU A 1 341 ? -19.32768 -42.96632 -21.11915 1.000 24.87738 ? 1800 LEU A HB3  1 
ATOM   5429 H  HG   . LEU A 1 341 ? -20.98125 -41.14903 -22.50227 1.000 26.67128 ? 1800 LEU A HG   1 
ATOM   5430 H  HD11 . LEU A 1 341 ? -20.12543 -42.06747 -24.50955 1.000 28.14619 ? 1800 LEU A HD11 1 
ATOM   5431 H  HD12 . LEU A 1 341 ? -19.03945 -41.20786 -23.73157 1.000 28.14619 ? 1800 LEU A HD12 1 
ATOM   5432 H  HD13 . LEU A 1 341 ? -18.99918 -42.79415 -23.65690 1.000 28.14619 ? 1800 LEU A HD13 1 
ATOM   5433 H  HD21 . LEU A 1 341 ? -21.92127 -43.13992 -23.38281 1.000 27.67877 ? 1800 LEU A HD21 1 
ATOM   5434 H  HD22 . LEU A 1 341 ? -21.04792 -43.95027 -22.33204 1.000 27.67877 ? 1800 LEU A HD22 1 
ATOM   5435 H  HD23 . LEU A 1 341 ? -22.17181 -42.94817 -21.82590 1.000 27.67877 ? 1800 LEU A HD23 1 
ATOM   5436 N  N    . VAL A 1 342 ? -19.37131 -41.10507 -17.76934 1.000 16.10722 ? 1801 VAL A N    1 
ATOM   5437 C  CA   . VAL A 1 342 ? -18.80452 -41.45771 -16.46889 1.000 15.84402 ? 1801 VAL A CA   1 
ATOM   5438 C  C    . VAL A 1 342 ? -19.88436 -41.28660 -15.40922 1.000 15.83350 ? 1801 VAL A C    1 
ATOM   5439 O  O    . VAL A 1 342 ? -20.68416 -40.33774 -15.47484 1.000 15.79665 ? 1801 VAL A O    1 
ATOM   5440 C  CB   . VAL A 1 342 ? -17.54011 -40.64911 -16.14817 1.000 15.67559 ? 1801 VAL A CB   1 
ATOM   5441 C  CG1  . VAL A 1 342 ? -16.36818 -41.15741 -16.98313 1.000 15.94404 ? 1801 VAL A CG1  1 
ATOM   5442 C  CG2  . VAL A 1 342 ? -17.79824 -39.16345 -16.36691 1.000 16.16512 ? 1801 VAL A CG2  1 
ATOM   5443 H  H    . VAL A 1 342 ? -19.56892 -40.27242 -17.85447 1.000 19.33146 ? 1801 VAL A H    1 
ATOM   5444 H  HA   . VAL A 1 342 ? -18.54093 -42.39112 -16.48215 1.000 19.01563 ? 1801 VAL A HA   1 
ATOM   5445 H  HB   . VAL A 1 342 ? -17.30098 -40.76456 -15.21523 1.000 18.81350 ? 1801 VAL A HB   1 
ATOM   5446 H  HG11 . VAL A 1 342 ? -15.60803 -40.56944 -16.85133 1.000 19.13564 ? 1801 VAL A HG11 1 
ATOM   5447 H  HG12 . VAL A 1 342 ? -16.14391 -42.05699 -16.69791 1.000 19.13564 ? 1801 VAL A HG12 1 
ATOM   5448 H  HG13 . VAL A 1 342 ? -16.62506 -41.16134 -17.91849 1.000 19.13564 ? 1801 VAL A HG13 1 
ATOM   5449 H  HG21 . VAL A 1 342 ? -17.02843 -38.66038 -16.05836 1.000 19.40094 ? 1801 VAL A HG21 1 
ATOM   5450 H  HG22 . VAL A 1 342 ? -17.94032 -39.00354 -17.31303 1.000 19.40094 ? 1801 VAL A HG22 1 
ATOM   5451 H  HG23 . VAL A 1 342 ? -18.58649 -38.90267 -15.86534 1.000 19.40094 ? 1801 VAL A HG23 1 
ATOM   5452 N  N    . PRO A 1 343 ? -19.93196 -42.17007 -14.41945 1.000 16.18617 ? 1802 PRO A N    1 
ATOM   5453 C  CA   . PRO A 1 343 ? -21.02774 -42.16199 -13.45222 1.000 16.24407 ? 1802 PRO A CA   1 
ATOM   5454 C  C    . PRO A 1 343 ? -20.78610 -41.17309 -12.32909 1.000 15.68611 ? 1802 PRO A C    1 
ATOM   5455 O  O    . PRO A 1 343 ? -19.64854 -40.73090 -12.10453 1.000 15.98615 ? 1802 PRO A O    1 
ATOM   5456 C  CB   . PRO A 1 343 ? -20.99871 -43.60026 -12.90947 1.000 17.45211 ? 1802 PRO A CB   1 
ATOM   5457 C  CG   . PRO A 1 343 ? -19.52985 -43.93519 -12.97323 1.000 17.52581 ? 1802 PRO A CG   1 
ATOM   5458 C  CD   . PRO A 1 343 ? -19.06708 -43.35180 -14.27009 1.000 16.88625 ? 1802 PRO A CD   1 
ATOM   5459 H  HA   . PRO A 1 343 ? -21.87013 -41.96145 -13.88934 1.000 19.49569 ? 1802 PRO A HA   1 
ATOM   5460 H  HB2  . PRO A 1 343 ? -21.33238 -43.62844 -11.99910 1.000 20.94533 ? 1802 PRO A HB2  1 
ATOM   5461 H  HB3  . PRO A 1 343 ? -21.52416 -44.18880 -13.47376 1.000 20.94533 ? 1802 PRO A HB3  1 
ATOM   5462 H  HG2  . PRO A 1 343 ? -19.06414 -43.53183 -12.22402 1.000 21.03376 ? 1802 PRO A HG2  1 
ATOM   5463 H  HG3  . PRO A 1 343 ? -19.40748 -44.89736 -12.96081 1.000 21.03376 ? 1802 PRO A HG3  1 
ATOM   5464 H  HD2  . PRO A 1 343 ? -18.13292 -43.09502 -14.22206 1.000 20.26630 ? 1802 PRO A HD2  1 
ATOM   5465 H  HD3  . PRO A 1 343 ? -19.20243 -43.97610 -15.00005 1.000 20.26630 ? 1802 PRO A HD3  1 
ATOM   5466 N  N    . PRO A 1 344 ? -21.82459 -40.85056 -11.56354 1.000 15.45450 ? 1803 PRO A N    1 
ATOM   5467 C  CA   . PRO A 1 344 ? -21.61853 -40.10126 -10.31801 1.000 14.97550 ? 1803 PRO A CA   1 
ATOM   5468 C  C    . PRO A 1 344 ? -20.62313 -40.85613 -9.45730  1.000 14.80969 ? 1803 PRO A C    1 
ATOM   5469 O  O    . PRO A 1 344 ? -20.67578 -42.08266 -9.35218  1.000 15.23079 ? 1803 PRO A O    1 
ATOM   5470 C  CB   . PRO A 1 344 ? -23.02258 -40.03322 -9.69696  1.000 15.51241 ? 1803 PRO A CB   1 
ATOM   5471 C  CG   . PRO A 1 344 ? -23.95961 -40.29003 -10.85451 1.000 15.47819 ? 1803 PRO A CG   1 
ATOM   5472 C  CD   . PRO A 1 344 ? -23.23591 -41.23574 -11.75683 1.000 15.55715 ? 1803 PRO A CD   1 
ATOM   5473 H  HA   . PRO A 1 344 ? -21.31705 -39.19224 -10.47196 1.000 17.97340 ? 1803 PRO A HA   1 
ATOM   5474 H  HB2  . PRO A 1 344 ? -23.11707 -40.71492 -9.01339  1.000 18.61768 ? 1803 PRO A HB2  1 
ATOM   5475 H  HB3  . PRO A 1 344 ? -23.17412 -39.15535 -9.31321  1.000 18.61768 ? 1803 PRO A HB3  1 
ATOM   5476 H  HG2  . PRO A 1 344 ? -24.78250 -40.68688 -10.52853 1.000 18.57663 ? 1803 PRO A HG2  1 
ATOM   5477 H  HG3  . PRO A 1 344 ? -24.15174 -39.45659 -11.31207 1.000 18.57663 ? 1803 PRO A HG3  1 
ATOM   5478 H  HD2  . PRO A 1 344 ? -23.38518 -42.15572 -11.48804 1.000 18.67137 ? 1803 PRO A HD2  1 
ATOM   5479 H  HD3  . PRO A 1 344 ? -23.50688 -41.11167 -12.67991 1.000 18.67137 ? 1803 PRO A HD3  1 
ATOM   5480 N  N    . GLY A 1 345 ? -19.63969 -40.13203 -8.94613  1.000 14.45965 ? 1804 GLY A N    1 
ATOM   5481 C  CA   . GLY A 1 345 ? -18.57983 -40.69410 -8.15406  1.000 13.98854 ? 1804 GLY A CA   1 
ATOM   5482 C  C    . GLY A 1 345 ? -17.27513 -40.90924 -8.88240  1.000 13.35689 ? 1804 GLY A C    1 
ATOM   5483 O  O    . GLY A 1 345 ? -16.26162 -41.20506 -8.22511  1.000 14.68073 ? 1804 GLY A O    1 
ATOM   5484 H  H    . GLY A 1 345 ? -19.56889 -39.28160 -9.05275  1.000 17.35438 ? 1804 GLY A H    1 
ATOM   5485 H  HA2  . GLY A 1 345 ? -18.40487 -40.10113 -7.40661  1.000 16.78904 ? 1804 GLY A HA2  1 
ATOM   5486 H  HA3  . GLY A 1 345 ? -18.87151 -41.55416 -7.81330  1.000 16.78904 ? 1804 GLY A HA3  1 
ATOM   5487 N  N    . TYR A 1 346 ? -17.25176 -40.73943 -10.21178 1.000 13.07264 ? 1805 TYR A N    1 
ATOM   5488 C  CA   . TYR A 1 346 ? -15.98975 -40.82884 -10.94337 1.000 12.99632 ? 1805 TYR A CA   1 
ATOM   5489 C  C    . TYR A 1 346 ? -15.04219 -39.70043 -10.55032 1.000 13.15160 ? 1805 TYR A C    1 
ATOM   5490 O  O    . TYR A 1 346 ? -13.81572 -39.88207 -10.53352 1.000 14.26489 ? 1805 TYR A O    1 
ATOM   5491 C  CB   . TYR A 1 346 ? -16.25668 -40.80119 -12.45223 1.000 13.80167 ? 1805 TYR A CB   1 
ATOM   5492 C  CG   . TYR A 1 346 ? -14.99695 -40.99929 -13.27391 1.000 13.80694 ? 1805 TYR A CG   1 
ATOM   5493 C  CD1  . TYR A 1 346 ? -14.37903 -42.24047 -13.36142 1.000 14.45702 ? 1805 TYR A CD1  1 
ATOM   5494 C  CD2  . TYR A 1 346 ? -14.41356 -39.93231 -13.93600 1.000 13.74377 ? 1805 TYR A CD2  1 
ATOM   5495 C  CE1  . TYR A 1 346 ? -13.22420 -42.40043 -14.08977 1.000 15.10709 ? 1805 TYR A CE1  1 
ATOM   5496 C  CE2  . TYR A 1 346 ? -13.25948 -40.07795 -14.67260 1.000 13.97012 ? 1805 TYR A CE2  1 
ATOM   5497 C  CZ   . TYR A 1 346 ? -12.66171 -41.32663 -14.75326 1.000 14.30963 ? 1805 TYR A CZ   1 
ATOM   5498 O  OH   . TYR A 1 346 ? -11.49968 -41.52267 -15.47799 1.000 14.79916 ? 1805 TYR A OH   1 
ATOM   5499 H  H    . TYR A 1 346 ? -17.94005 -40.57499 -10.70047 1.000 15.68997 ? 1805 TYR A H    1 
ATOM   5500 H  HA   . TYR A 1 346 ? -15.55937 -41.67213 -10.73233 1.000 15.59838 ? 1805 TYR A HA   1 
ATOM   5501 H  HB2  . TYR A 1 346 ? -16.87663 -41.51275 -12.67639 1.000 16.56480 ? 1805 TYR A HB2  1 
ATOM   5502 H  HB3  . TYR A 1 346 ? -16.63829 -39.94163 -12.68977 1.000 16.56480 ? 1805 TYR A HB3  1 
ATOM   5503 H  HD1  . TYR A 1 346 ? -14.75077 -42.97120 -12.92241 1.000 17.35122 ? 1805 TYR A HD1  1 
ATOM   5504 H  HD2  . TYR A 1 346 ? -14.81237 -39.09392 -13.88164 1.000 16.49533 ? 1805 TYR A HD2  1 
ATOM   5505 H  HE1  . TYR A 1 346 ? -12.81907 -43.23626 -14.13629 1.000 18.13131 ? 1805 TYR A HE1  1 
ATOM   5506 H  HE2  . TYR A 1 346 ? -12.88542 -39.34784 -15.11070 1.000 16.76694 ? 1805 TYR A HE2  1 
ATOM   5507 H  HH   . TYR A 1 346 ? -11.26058 -40.80233 -15.83790 1.000 17.76179 ? 1805 TYR A HH   1 
ATOM   5508 N  N    . GLY A 1 347 ? -15.59253 -38.53869 -10.23014 1.000 12.79366 ? 1806 GLY A N    1 
ATOM   5509 C  CA   . GLY A 1 347 ? -14.76326 -37.39813 -9.91579  1.000 12.55942 ? 1806 GLY A CA   1 
ATOM   5510 C  C    . GLY A 1 347 ? -14.12083 -37.49607 -8.54516  1.000 12.91999 ? 1806 GLY A C    1 
ATOM   5511 O  O    . GLY A 1 347 ? -14.61761 -38.17859 -7.63419  1.000 13.30688 ? 1806 GLY A O    1 
ATOM   5512 H  H    . GLY A 1 347 ? -16.43846 -38.38931 -10.18896 1.000 15.35519 ? 1806 GLY A H    1 
ATOM   5513 H  HA2  . GLY A 1 347 ? -14.05761 -37.32462 -10.57727 1.000 15.07410 ? 1806 GLY A HA2  1 
ATOM   5514 H  HA3  . GLY A 1 347 ? -15.30446 -36.59353 -9.94062  1.000 15.07410 ? 1806 GLY A HA3  1 
ATOM   5515 N  N    . GLN A 1 348 ? -12.99369 -36.78236 -8.40557  1.000 12.66733 ? 1807 GLN A N    1 
ATOM   5516 C  CA   . GLN A 1 348 ? -12.18047 -36.82884 -7.20499  1.000 12.07515 ? 1807 GLN A CA   1 
ATOM   5517 C  C    . GLN A 1 348 ? -11.84089 -35.42221 -6.71321  1.000 11.30927 ? 1807 GLN A C    1 
ATOM   5518 O  O    . GLN A 1 348 ? -11.80655 -34.46617 -7.48222  1.000 12.00935 ? 1807 GLN A O    1 
ATOM   5519 C  CB   . GLN A 1 348 ? -10.85297 -37.55711 -7.47978  1.000 12.62785 ? 1807 GLN A CB   1 
ATOM   5520 C  CG   . GLN A 1 348 ? -11.06534 -38.98947 -7.92451  1.000 13.44111 ? 1807 GLN A CG   1 
ATOM   5521 C  CD   . GLN A 1 348 ? -9.76431  -39.70615 -8.20050  1.000 15.48082 ? 1807 GLN A CD   1 
ATOM   5522 O  OE1  . GLN A 1 348 ? -8.69073  -39.25738 -7.79320  1.000 16.90731 ? 1807 GLN A OE1  1 
ATOM   5523 N  NE2  . GLN A 1 348 ? -9.85260  -40.83326 -8.90088  1.000 16.83625 ? 1807 GLN A NE2  1 
ATOM   5524 H  H    . GLN A 1 348 ? -12.68211 -36.25655 -9.01058  1.000 15.20359 ? 1807 GLN A H    1 
ATOM   5525 H  HA   . GLN A 1 348 ? -12.68931 -37.28039 -6.51356  1.000 14.49298 ? 1807 GLN A HA   1 
ATOM   5526 H  HB2  . GLN A 1 348 ? -10.37411 -37.09014 -8.18230  1.000 15.15622 ? 1807 GLN A HB2  1 
ATOM   5527 H  HB3  . GLN A 1 348 ? -10.32276 -37.56806 -6.66758  1.000 15.15622 ? 1807 GLN A HB3  1 
ATOM   5528 H  HG2  . GLN A 1 348 ? -11.53323 -39.47273 -7.22563  1.000 16.13212 ? 1807 GLN A HG2  1 
ATOM   5529 H  HG3  . GLN A 1 348 ? -11.59075 -38.99404 -8.73988  1.000 16.13212 ? 1807 GLN A HG3  1 
ATOM   5530 H  HE21 . GLN A 1 348 ? -10.62009 -41.11423 -9.16850  1.000 20.20629 ? 1807 GLN A HE21 1 
ATOM   5531 H  HE22 . GLN A 1 348 ? -9.14220  -41.28114 -9.08617  1.000 20.20629 ? 1807 GLN A HE22 1 
ATOM   5532 N  N    . ASP A 1 349 ? -11.54886 -35.34635 -5.41442  1.000 11.81986 ? 1808 ASP A N    1 
ATOM   5533 C  CA   . ASP A 1 349 ? -11.12056 -34.11588 -4.75079  1.000 11.36981 ? 1808 ASP A CA   1 
ATOM   5534 C  C    . ASP A 1 349 ? -9.64468  -33.90353 -5.05690  1.000 11.37770 ? 1808 ASP A C    1 
ATOM   5535 O  O    . ASP A 1 349 ? -8.77928  -34.62944 -4.54598  1.000 11.99619 ? 1808 ASP A O    1 
ATOM   5536 C  CB   . ASP A 1 349 ? -11.34937 -34.29790 -3.25934  1.000 11.99093 ? 1808 ASP A CB   1 
ATOM   5537 C  CG   . ASP A 1 349 ? -11.04703 -33.06071 -2.44420  1.000 13.04369 ? 1808 ASP A CG   1 
ATOM   5538 O  OD1  . ASP A 1 349 ? -10.46766 -32.07350 -2.96291  1.000 12.77787 ? 1808 ASP A OD1  1 
ATOM   5539 O  OD2  . ASP A 1 349 ? -11.40182 -33.09678 -1.24954  1.000 15.15710 ? 1808 ASP A OD2  1 
ATOM   5540 H  H    . ASP A 1 349 ? -11.59267 -36.01715 -4.87803  1.000 14.18663 ? 1808 ASP A H    1 
ATOM   5541 H  HA   . ASP A 1 349 ? -11.61108 -33.34240 -5.07019  1.000 13.64656 ? 1808 ASP A HA   1 
ATOM   5542 H  HB2  . ASP A 1 349 ? -12.27957 -34.52989 -3.11169  1.000 14.39192 ? 1808 ASP A HB2  1 
ATOM   5543 H  HB3  . ASP A 1 349 ? -10.77481 -35.01102 -2.93957  1.000 14.39192 ? 1808 ASP A HB3  1 
ATOM   5544 N  N    . VAL A 1 350 ? -9.35456  -32.90895 -5.89652  1.000 11.30664 ? 1809 VAL A N    1 
ATOM   5545 C  CA   . VAL A 1 350 ? -7.97845  -32.69413 -6.32614  1.000 11.42771 ? 1809 VAL A CA   1 
ATOM   5546 C  C    . VAL A 1 350 ? -7.06302  -32.29452 -5.18202  1.000 11.45929 ? 1809 VAL A C    1 
ATOM   5547 O  O    . VAL A 1 350 ? -5.83936  -32.46383 -5.28510  1.000 12.19359 ? 1809 VAL A O    1 
ATOM   5548 C  CB   . VAL A 1 350 ? -7.88719  -31.69410 -7.50126  1.000 12.26991 ? 1809 VAL A CB   1 
ATOM   5549 C  CG1  . VAL A 1 350 ? -8.74066  -32.13398 -8.67973  1.000 13.12528 ? 1809 VAL A CG1  1 
ATOM   5550 C  CG2  . VAL A 1 350 ? -8.28996  -30.26386 -7.07570  1.000 12.75418 ? 1809 VAL A CG2  1 
ATOM   5551 H  H    . VAL A 1 350 ? -9.92662  -32.35668 -6.22417  1.000 13.57077 ? 1809 VAL A H    1 
ATOM   5552 H  HA   . VAL A 1 350 ? -7.66078  -33.54688 -6.66201  1.000 13.71605 ? 1809 VAL A HA   1 
ATOM   5553 H  HB   . VAL A 1 350 ? -6.95853  -31.67787 -7.78096  1.000 14.72669 ? 1809 VAL A HB   1 
ATOM   5554 H  HG11 . VAL A 1 350 ? -8.61810  -31.50717 -9.40980  1.000 15.75313 ? 1809 VAL A HG11 1 
ATOM   5555 H  HG12 . VAL A 1 350 ? -8.46411  -33.02172 -8.95600  1.000 15.75313 ? 1809 VAL A HG12 1 
ATOM   5556 H  HG13 . VAL A 1 350 ? -9.67169  -32.14719 -8.40788  1.000 15.75313 ? 1809 VAL A HG13 1 
ATOM   5557 H  HG21 . VAL A 1 350 ? -8.31623  -29.69610 -7.86174  1.000 15.30781 ? 1809 VAL A HG21 1 
ATOM   5558 H  HG22 . VAL A 1 350 ? -9.16556  -30.29305 -6.65933  1.000 15.30781 ? 1809 VAL A HG22 1 
ATOM   5559 H  HG23 . VAL A 1 350 ? -7.63496  -29.92574 -6.44518  1.000 15.30781 ? 1809 VAL A HG23 1 
ATOM   5560 N  N    . ARG A 1 351 ? -7.60419  -31.72659 -4.10376  1.000 11.40402 ? 1810 ARG A N    1 
ATOM   5561 C  CA   . ARG A 1 351 ? -6.78171  -31.34004 -2.96936  1.000 11.65405 ? 1810 ARG A CA   1 
ATOM   5562 C  C    . ARG A 1 351 ? -6.22741  -32.53554 -2.20331  1.000 12.86209 ? 1810 ARG A C    1 
ATOM   5563 O  O    . ARG A 1 351 ? -5.34211  -32.34858 -1.37002  1.000 14.82021 ? 1810 ARG A O    1 
ATOM   5564 C  CB   . ARG A 1 351 ? -7.54951  -30.39982 -2.04332  1.000 11.94882 ? 1810 ARG A CB   1 
ATOM   5565 C  CG   . ARG A 1 351 ? -7.62136  -28.96686 -2.55845  1.000 12.33834 ? 1810 ARG A CG   1 
ATOM   5566 C  CD   . ARG A 1 351 ? -6.33959  -28.19178 -2.28674  1.000 12.71733 ? 1810 ARG A CD   1 
ATOM   5567 N  NE   . ARG A 1 351 ? -6.52109  -26.79287 -2.64733  1.000 12.39887 ? 1810 ARG A NE   1 
ATOM   5568 C  CZ   . ARG A 1 351 ? -5.94287  -26.18004 -3.67009  1.000 11.00397 ? 1810 ARG A CZ   1 
ATOM   5569 N  NH1  . ARG A 1 351 ? -5.07331  -26.80216 -4.45116  1.000 10.98555 ? 1810 ARG A NH1  1 
ATOM   5570 N  NH2  . ARG A 1 351 ? -6.26629  -24.92011 -3.93720  1.000 11.40402 ? 1810 ARG A NH2  1 
ATOM   5571 H  H    . ARG A 1 351 ? -8.44195  -31.55693 -4.00906  1.000 13.68762 ? 1810 ARG A H    1 
ATOM   5572 H  HA   . ARG A 1 351 ? -6.01898  -30.83874 -3.29774  1.000 13.98766 ? 1810 ARG A HA   1 
ATOM   5573 H  HB2  . ARG A 1 351 ? -8.45747  -30.72739 -1.94739  1.000 14.34138 ? 1810 ARG A HB2  1 
ATOM   5574 H  HB3  . ARG A 1 351 ? -7.10962  -30.38357 -1.17895  1.000 14.34138 ? 1810 ARG A HB3  1 
ATOM   5575 H  HG2  . ARG A 1 351 ? -7.76845  -28.98009 -3.51714  1.000 14.80881 ? 1810 ARG A HG2  1 
ATOM   5576 H  HG3  . ARG A 1 351 ? -8.35190  -28.50603 -2.11705  1.000 14.80881 ? 1810 ARG A HG3  1 
ATOM   5577 H  HD2  . ARG A 1 351 ? -6.11886  -28.24464 -1.34367  1.000 15.26360 ? 1810 ARG A HD2  1 
ATOM   5578 H  HD3  . ARG A 1 351 ? -5.61601  -28.55941 -2.81794  1.000 15.26360 ? 1810 ARG A HD3  1 
ATOM   5579 H  HE   . ARG A 1 351 ? -7.04820  -26.32467 -2.15484  1.000 14.88144 ? 1810 ARG A HE   1 
ATOM   5580 H  HH11 . ARG A 1 351 ? -4.87128  -27.62437 -4.30030  1.000 13.18545 ? 1810 ARG A HH11 1 
ATOM   5581 H  HH12 . ARG A 1 351 ? -4.71055  -26.38402 -5.10931  1.000 13.18545 ? 1810 ARG A HH12 1 
ATOM   5582 H  HH21 . ARG A 1 351 ? -5.89738  -24.51240 -4.59847  1.000 13.68762 ? 1810 ARG A HH21 1 
ATOM   5583 H  HH22 . ARG A 1 351 ? -6.84465  -24.51185 -3.44891  1.000 13.68762 ? 1810 ARG A HH22 1 
ATOM   5584 N  N    . LYS A 1 352 ? -6.75043  -33.73971 -2.44469  1.000 13.92801 ? 1811 LYS A N    1 
ATOM   5585 C  CA   . LYS A 1 352 ? -6.21759  -34.94896 -1.83625  1.000 15.33081 ? 1811 LYS A CA   1 
ATOM   5586 C  C    . LYS A 1 352 ? -5.11791  -35.58204 -2.66983  1.000 15.57820 ? 1811 LYS A C    1 
ATOM   5587 O  O    . LYS A 1 352 ? -4.42049  -36.47299 -2.17167  1.000 17.33367 ? 1811 LYS A O    1 
ATOM   5588 C  CB   . LYS A 1 352 ? -7.34671  -35.95679 -1.61599  1.000 17.18103 ? 1811 LYS A CB   1 
ATOM   5589 C  CG   . LYS A 1 352 ? -8.32364  -35.50407 -0.52163  1.000 21.12887 ? 1811 LYS A CG   1 
ATOM   5590 C  CD   . LYS A 1 352 ? -9.50331  -36.44871 -0.39350  1.000 24.97933 ? 1811 LYS A CD   1 
ATOM   5591 C  CE   . LYS A 1 352 ? -9.25376  -37.58175 0.56668   1.000 27.43752 ? 1811 LYS A CE   1 
ATOM   5592 N  NZ   . LYS A 1 352 ? -10.22444 -38.69540 0.31197   1.000 27.60859 ? 1811 LYS A NZ   1 
ATOM   5593 H  H    . LYS A 1 352 ? -7.42178  -33.87884 -2.96386  1.000 16.71641 ? 1811 LYS A H    1 
ATOM   5594 H  HA   . LYS A 1 352 ? -5.84237  -34.73428 -0.96791  1.000 18.39977 ? 1811 LYS A HA   1 
ATOM   5595 H  HB2  . LYS A 1 352 ? -7.84468  -36.06155 -2.44180  1.000 20.62003 ? 1811 LYS A HB2  1 
ATOM   5596 H  HB3  . LYS A 1 352 ? -6.96545  -36.80760 -1.34828  1.000 20.62003 ? 1811 LYS A HB3  1 
ATOM   5597 H  HG2  . LYS A 1 352 ? -7.86073  -35.47920 0.33042   1.000 25.35744 ? 1811 LYS A HG2  1 
ATOM   5598 H  HG3  . LYS A 1 352 ? -8.66328  -34.62224 -0.74053  1.000 25.35744 ? 1811 LYS A HG3  1 
ATOM   5599 H  HD2  . LYS A 1 352 ? -10.27193 -35.95102 -0.07343  1.000 29.97799 ? 1811 LYS A HD2  1 
ATOM   5600 H  HD3  . LYS A 1 352 ? -9.69536  -36.83246 -1.26341  1.000 29.97799 ? 1811 LYS A HD3  1 
ATOM   5601 H  HE2  . LYS A 1 352 ? -8.35298  -37.92043 0.44506   1.000 32.92782 ? 1811 LYS A HE2  1 
ATOM   5602 H  HE3  . LYS A 1 352 ? -9.37066  -37.26956 1.47760   1.000 32.92782 ? 1811 LYS A HE3  1 
ATOM   5603 H  HZ1  . LYS A 1 352 ? -10.13407 -38.99322 -0.52184  1.000 33.13311 ? 1811 LYS A HZ1  1 
ATOM   5604 H  HZ2  . LYS A 1 352 ? -10.07266 -39.36655 0.87644   1.000 33.13311 ? 1811 LYS A HZ2  1 
ATOM   5605 H  HZ3  . LYS A 1 352 ? -11.05788 -38.40483 0.42616   1.000 33.13311 ? 1811 LYS A HZ3  1 
ATOM   5606 N  N    . TRP A 1 353 ? -4.93624  -35.14688 -3.90635  1.000 14.71758 ? 1812 TRP A N    1 
ATOM   5607 C  CA   . TRP A 1 353 ? -3.85319  -35.67569 -4.71372  1.000 14.92813 ? 1812 TRP A CA   1 
ATOM   5608 C  C    . TRP A 1 353 ? -2.52338  -35.11395 -4.20408  1.000 16.98890 ? 1812 TRP A C    1 
ATOM   5609 O  O    . TRP A 1 353 ? -2.44991  -33.94549 -3.81644  1.000 17.25209 ? 1812 TRP A O    1 
ATOM   5610 C  CB   . TRP A 1 353 ? -4.04830  -35.26261 -6.16503  1.000 14.28331 ? 1812 TRP A CB   1 
ATOM   5611 C  CG   . TRP A 1 353 ? -5.27746  -35.76714 -6.83688  1.000 13.61481 ? 1812 TRP A CG   1 
ATOM   5612 C  CD1  . TRP A 1 353 ? -6.17623  -36.67930 -6.35358  1.000 14.07013 ? 1812 TRP A CD1  1 
ATOM   5613 C  CD2  . TRP A 1 353 ? -5.73617  -35.40350 -8.14443  1.000 13.73588 ? 1812 TRP A CD2  1 
ATOM   5614 N  NE1  . TRP A 1 353 ? -7.15502  -36.89412 -7.27680  1.000 14.00433 ? 1812 TRP A NE1  1 
ATOM   5615 C  CE2  . TRP A 1 353 ? -6.91114  -36.13316 -8.38491  1.000 13.57270 ? 1812 TRP A CE2  1 
ATOM   5616 C  CE3  . TRP A 1 353 ? -5.25699  -34.54602 -9.14692  1.000 14.01223 ? 1812 TRP A CE3  1 
ATOM   5617 C  CZ2  . TRP A 1 353 ? -7.60258  -36.03830 -9.55438  1.000 13.57533 ? 1812 TRP A CZ2  1 
ATOM   5618 C  CZ3  . TRP A 1 353 ? -5.96265  -34.44678 -10.31488 1.000 14.71757 ? 1812 TRP A CZ3  1 
ATOM   5619 C  CH2  . TRP A 1 353 ? -7.13241  -35.18684 -10.50922 1.000 14.30700 ? 1812 TRP A CH2  1 
ATOM   5620 H  H    . TRP A 1 353 ? -5.42042  -34.55298 -4.29680  1.000 17.66389 ? 1812 TRP A H    1 
ATOM   5621 H  HA   . TRP A 1 353 ? -3.83304  -36.64400 -4.66022  1.000 17.91655 ? 1812 TRP A HA   1 
ATOM   5622 H  HB2  . TRP A 1 353 ? -4.08131  -34.29385 -6.20119  1.000 17.14277 ? 1812 TRP A HB2  1 
ATOM   5623 H  HB3  . TRP A 1 353 ? -3.29063  -35.58804 -6.67585  1.000 17.14277 ? 1812 TRP A HB3  1 
ATOM   5624 H  HD1  . TRP A 1 353 ? -6.12637  -37.09036 -5.52085  1.000 16.88695 ? 1812 TRP A HD1  1 
ATOM   5625 H  HE1  . TRP A 1 353 ? -7.82309  -37.42646 -7.17734  1.000 16.80799 ? 1812 TRP A HE1  1 
ATOM   5626 H  HE3  . TRP A 1 353 ? -4.47683  -34.05598 -9.02005  1.000 16.81747 ? 1812 TRP A HE3  1 
ATOM   5627 H  HZ2  . TRP A 1 353 ? -8.37274  -36.53964 -9.69724  1.000 16.29320 ? 1812 TRP A HZ2  1 
ATOM   5628 H  HZ3  . TRP A 1 353 ? -5.66040  -33.88014 -10.98754 1.000 17.66388 ? 1812 TRP A HZ3  1 
ATOM   5629 H  HH2  . TRP A 1 353 ? -7.60031  -35.09625 -11.30782 1.000 17.17119 ? 1812 TRP A HH2  1 
ATOM   5630 N  N    . PRO A 1 354 ? -1.45235  -35.89981 -4.20733  1.000 19.31286 ? 1813 PRO A N    1 
ATOM   5631 C  CA   . PRO A 1 354 ? -0.16780  -35.35105 -3.74210  1.000 20.06295 ? 1813 PRO A CA   1 
ATOM   5632 C  C    . PRO A 1 354 ? 0.23954   -34.06639 -4.44652  1.000 19.47341 ? 1813 PRO A C    1 
ATOM   5633 O  O    . PRO A 1 354 ? 0.78573   -33.15419 -3.81343  1.000 20.34193 ? 1813 PRO A O    1 
ATOM   5634 C  CB   . PRO A 1 354 ? 0.81803   -36.49856 -4.00395  1.000 21.52102 ? 1813 PRO A CB   1 
ATOM   5635 C  CG   . PRO A 1 354 ? 0.01368   -37.69019 -3.88368  1.000 21.66314 ? 1813 PRO A CG   1 
ATOM   5636 C  CD   . PRO A 1 354 ? -1.35159  -37.34325 -4.48137  1.000 20.78935 ? 1813 PRO A CD   1 
ATOM   5637 H  HA   . PRO A 1 354 ? -0.21085  -35.18469 -2.78744  1.000 24.07834 ? 1813 PRO A HA   1 
ATOM   5638 H  HB2  . PRO A 1 354 ? 1.19404   -36.41841 -4.89451  1.000 25.82802 ? 1813 PRO A HB2  1 
ATOM   5639 H  HB3  . PRO A 1 354 ? 1.52709   -36.48654 -3.34214  1.000 25.82802 ? 1813 PRO A HB3  1 
ATOM   5640 H  HG2  . PRO A 1 354 ? 0.42912   -38.41513 -4.37641  1.000 25.99857 ? 1813 PRO A HG2  1 
ATOM   5641 H  HG3  . PRO A 1 354 ? -0.07327  -37.93188 -2.94831  1.000 25.99857 ? 1813 PRO A HG3  1 
ATOM   5642 H  HD2  . PRO A 1 354 ? -1.37089  -37.52019 -5.43490  1.000 24.95002 ? 1813 PRO A HD2  1 
ATOM   5643 H  HD3  . PRO A 1 354 ? -2.06181  -37.83353 -4.03853  1.000 24.95002 ? 1813 PRO A HD3  1 
ATOM   5644 N  N    . GLN A 1 355 ? -0.02861  -33.97170 -5.74482  1.000 18.54172 ? 1814 GLN A N    1 
ATOM   5645 C  CA   . GLN A 1 355 ? 0.28983   -32.80618 -6.54903  1.000 18.88123 ? 1814 GLN A CA   1 
ATOM   5646 C  C    . GLN A 1 355 ? -0.70320  -31.66215 -6.35424  1.000 17.03627 ? 1814 GLN A C    1 
ATOM   5647 O  O    . GLN A 1 355 ? -0.46019  -30.55019 -6.83409  1.000 17.68635 ? 1814 GLN A O    1 
ATOM   5648 C  CB   . GLN A 1 355 ? 0.39541   -33.26606 -8.01050  1.000 21.29994 ? 1814 GLN A CB   1 
ATOM   5649 C  CG   . GLN A 1 355 ? -0.80362  -33.97154 -8.67404  1.000 21.91580 ? 1814 GLN A CG   1 
ATOM   5650 C  CD   . GLN A 1 355 ? -1.03428  -35.44588 -8.33990  1.000 22.07898 ? 1814 GLN A CD   1 
ATOM   5651 O  OE1  . GLN A 1 355 ? -0.58715  -35.96493 -7.34093  1.000 22.36323 ? 1814 GLN A OE1  1 
ATOM   5652 N  NE2  . GLN A 1 355 ? -1.72992  -36.12103 -9.23600  1.000 22.78170 ? 1814 GLN A NE2  1 
ATOM   5653 H  H    . GLN A 1 355 ? -0.40969  -34.59532 -6.19811  1.000 22.25286 ? 1814 GLN A H    1 
ATOM   5654 H  HA   . GLN A 1 355 ? 1.14886   -32.42765 -6.30473  1.000 22.66027 ? 1814 GLN A HA   1 
ATOM   5655 H  HB2  . GLN A 1 355 ? 0.57884   -32.47995 -8.54834  1.000 25.56272 ? 1814 GLN A HB2  1 
ATOM   5656 H  HB3  . GLN A 1 355 ? 1.13907   -33.88644 -8.06529  1.000 25.56272 ? 1814 GLN A HB3  1 
ATOM   5657 H  HG2  . GLN A 1 355 ? -1.60866  -33.49742 -8.41321  1.000 26.30176 ? 1814 GLN A HG2  1 
ATOM   5658 H  HG3  . GLN A 1 355 ? -0.68435  -33.91898 -9.63524  1.000 26.30176 ? 1814 GLN A HG3  1 
ATOM   5659 H  HE21 . GLN A 1 355 ? -2.01632  -35.72645 -9.94444  1.000 27.34083 ? 1814 GLN A HE21 1 
ATOM   5660 H  HE22 . GLN A 1 355 ? -1.89670  -36.95544 -9.11133  1.000 27.34083 ? 1814 GLN A HE22 1 
ATOM   5661 N  N    . GLY A 1 356 ? -1.80238  -31.89737 -5.63564  1.000 15.80981 ? 1815 GLY A N    1 
ATOM   5662 C  CA   . GLY A 1 356 ? -2.82050  -30.89487 -5.42995  1.000 14.98603 ? 1815 GLY A CA   1 
ATOM   5663 C  C    . GLY A 1 356 ? -2.75584  -30.13083 -4.13605  1.000 14.71758 ? 1815 GLY A C    1 
ATOM   5664 O  O    . GLY A 1 356 ? -3.59353  -29.24775 -3.90947  1.000 15.40450 ? 1815 GLY A O    1 
ATOM   5665 H  H    . GLY A 1 356 ? -1.97474  -32.64843 -5.25380  1.000 18.97457 ? 1815 GLY A H    1 
ATOM   5666 H  HA2  . GLY A 1 356 ? -2.76097  -30.24846 -6.15072  1.000 17.98603 ? 1815 GLY A HA2  1 
ATOM   5667 H  HA3  . GLY A 1 356 ? -3.68699  -31.32936 -5.46617  1.000 17.98603 ? 1815 GLY A HA3  1 
ATOM   5668 N  N    . ALA A 1 357 ? -1.78767  -30.41452 -3.28105  1.000 15.63347 ? 1816 ALA A N    1 
ATOM   5669 C  CA   . ALA A 1 357 ? -1.55960  -29.59045 -2.10623  1.000 16.19407 ? 1816 ALA A CA   1 
ATOM   5670 C  C    . ALA A 1 357 ? -0.89432  -28.27530 -2.50288  1.000 15.60189 ? 1816 ALA A C    1 
ATOM   5671 O  O    . ALA A 1 357 ? -0.06894  -28.22230 -3.41744  1.000 15.94404 ? 1816 ALA A O    1 
ATOM   5672 C  CB   . ALA A 1 357 ? -0.67192  -30.34734 -1.11821  1.000 17.06785 ? 1816 ALA A CB   1 
ATOM   5673 H  H    . ALA A 1 357 ? -1.24781  -31.07952 -3.35805  1.000 18.76296 ? 1816 ALA A H    1 
ATOM   5674 H  HA   . ALA A 1 357 ? -2.40314  -29.38336 -1.67444  1.000 19.43568 ? 1816 ALA A HA   1 
ATOM   5675 H  HB1  . ALA A 1 357 ? -0.52812  -29.79382 -0.33473  1.000 20.48422 ? 1816 ALA A HB1  1 
ATOM   5676 H  HB2  . ALA A 1 357 ? -1.11450  -31.17214 -0.86379  1.000 20.48422 ? 1816 ALA A HB2  1 
ATOM   5677 H  HB3  . ALA A 1 357 ? 0.17700   -30.54513 -1.54380  1.000 20.48422 ? 1816 ALA A HB3  1 
ATOM   5678 N  N    . VAL A 1 358 ? -1.26652  -27.20348 -1.81333  1.000 15.64926 ? 1817 VAL A N    1 
ATOM   5679 C  CA   . VAL A 1 358 ? -0.67088  -25.89914 -2.08911  1.000 15.39134 ? 1817 VAL A CA   1 
ATOM   5680 C  C    . VAL A 1 358 ? 0.68728   -25.86245 -1.40110  1.000 15.78876 ? 1817 VAL A C    1 
ATOM   5681 O  O    . VAL A 1 358 ? 0.76070   -26.04457 -0.18056  1.000 15.06235 ? 1817 VAL A O    1 
ATOM   5682 C  CB   . VAL A 1 358 ? -1.55721  -24.74730 -1.58986  1.000 14.76232 ? 1817 VAL A CB   1 
ATOM   5683 C  CG1  . VAL A 1 358 ? -0.86608  -23.42560 -1.89302  1.000 15.19131 ? 1817 VAL A CG1  1 
ATOM   5684 C  CG2  . VAL A 1 358 ? -2.94778  -24.82896 -2.19337  1.000 14.85970 ? 1817 VAL A CG2  1 
ATOM   5685 H  H    . VAL A 1 358 ? -1.85585  -27.20458 -1.18701  1.000 18.78192 ? 1817 VAL A H    1 
ATOM   5686 H  HA   . VAL A 1 358 ? -0.55999  -25.79422 -3.04702  1.000 18.47240 ? 1817 VAL A HA   1 
ATOM   5687 H  HB   . VAL A 1 358 ? -1.68065  -24.80960 -0.62976  1.000 17.71758 ? 1817 VAL A HB   1 
ATOM   5688 H  HG11 . VAL A 1 358 ? -1.50003  -22.70199 -1.76896  1.000 18.23238 ? 1817 VAL A HG11 1 
ATOM   5689 H  HG12 . VAL A 1 358 ? -0.11587  -23.31548 -1.28808  1.000 18.23238 ? 1817 VAL A HG12 1 
ATOM   5690 H  HG13 . VAL A 1 358 ? -0.55213  -23.43662 -2.81074  1.000 18.23238 ? 1817 VAL A HG13 1 
ATOM   5691 H  HG21 . VAL A 1 358 ? -3.46604  -24.06442 -1.89707  1.000 17.83443 ? 1817 VAL A HG21 1 
ATOM   5692 H  HG22 . VAL A 1 358 ? -2.87315  -24.82323 -3.16048  1.000 17.83443 ? 1817 VAL A HG22 1 
ATOM   5693 H  HG23 . VAL A 1 358 ? -3.37198  -25.65019 -1.89920  1.000 17.83443 ? 1817 VAL A HG23 1 
ATOM   5694 N  N    . PRO A 1 359 ? 1.78078   -25.59987 -2.11536  1.000 17.52317 ? 1818 PRO A N    1 
ATOM   5695 C  CA   . PRO A 1 359 ? 3.09213   -25.58758 -1.44944  1.000 17.71793 ? 1818 PRO A CA   1 
ATOM   5696 C  C    . PRO A 1 359 ? 3.17116   -24.51805 -0.36435  1.000 17.22051 ? 1818 PRO A C    1 
ATOM   5697 O  O    . PRO A 1 359 ? 2.56932   -23.44832 -0.46846  1.000 16.98627 ? 1818 PRO A O    1 
ATOM   5698 C  CB   . PRO A 1 359 ? 4.07640   -25.32852 -2.60335  1.000 18.75753 ? 1818 PRO A CB   1 
ATOM   5699 C  CG   . PRO A 1 359 ? 3.33900   -25.82179 -3.82835  1.000 19.75765 ? 1818 PRO A CG   1 
ATOM   5700 C  CD   . PRO A 1 359 ? 1.90305   -25.38085 -3.56852  1.000 18.96545 ? 1818 PRO A CD   1 
ATOM   5701 H  HA   . PRO A 1 359 ? 3.28555   -26.45064 -1.05117  1.000 21.26432 ? 1818 PRO A HA   1 
ATOM   5702 H  HB2  . PRO A 1 359 ? 4.27233   -24.38082 -2.66947  1.000 22.51183 ? 1818 PRO A HB2  1 
ATOM   5703 H  HB3  . PRO A 1 359 ? 4.89604   -25.82770 -2.46229  1.000 22.51183 ? 1818 PRO A HB3  1 
ATOM   5704 H  HG2  . PRO A 1 359 ? 3.69698   -25.40665 -4.62860  1.000 23.71198 ? 1818 PRO A HG2  1 
ATOM   5705 H  HG3  . PRO A 1 359 ? 3.40543   -26.78706 -3.89725  1.000 23.71198 ? 1818 PRO A HG3  1 
ATOM   5706 H  HD2  . PRO A 1 359 ? 1.77631   -24.44614 -3.79470  1.000 22.76134 ? 1818 PRO A HD2  1 
ATOM   5707 H  HD3  . PRO A 1 359 ? 1.27262   -25.92971 -4.06068  1.000 22.76134 ? 1818 PRO A HD3  1 
ATOM   5708 N  N    . GLN A 1 360 ? 3.89647   -24.83247 0.71220   1.000 18.48118 ? 1819 GLN A N    1 
ATOM   5709 C  CA   . GLN A 1 360 ? 4.08973   -23.86146 1.78286   1.000 20.19981 ? 1819 GLN A CA   1 
ATOM   5710 C  C    . GLN A 1 360 ? 5.44027   -24.06682 2.45387   1.000 21.38680 ? 1819 GLN A C    1 
ATOM   5711 O  O    . GLN A 1 360 ? 6.01451   -25.15303 2.42136   1.000 21.51313 ? 1819 GLN A O    1 
ATOM   5712 C  CB   . GLN A 1 360 ? 2.98316   -23.92549 2.85328   1.000 21.69999 ? 1819 GLN A CB   1 
ATOM   5713 C  CG   . GLN A 1 360 ? 3.07372   -25.12128 3.75895   1.000 23.61338 ? 1819 GLN A CG   1 
ATOM   5714 C  CD   . GLN A 1 360 ? 1.91900   -25.22634 4.73761   1.000 25.68468 ? 1819 GLN A CD   1 
ATOM   5715 O  OE1  . GLN A 1 360 ? 1.05577   -26.08395 4.59158   1.000 27.18749 ? 1819 GLN A OE1  1 
ATOM   5716 N  NE2  . GLN A 1 360 ? 1.88537   -24.33989 5.72094   1.000 25.80311 ? 1819 GLN A NE2  1 
ATOM   5717 H  H    . GLN A 1 360 ? 4.27993   -25.59141 0.84089   1.000 22.18022 ? 1819 GLN A H    1 
ATOM   5718 H  HA   . GLN A 1 360 ? 4.07956   -22.98326 1.37109   1.000 24.24257 ? 1819 GLN A HA   1 
ATOM   5719 H  HB2  . GLN A 1 360 ? 3.04076   -23.13130 3.40721   1.000 26.04279 ? 1819 GLN A HB2  1 
ATOM   5720 H  HB3  . GLN A 1 360 ? 2.12201   -23.95767 2.40800   1.000 26.04279 ? 1819 GLN A HB3  1 
ATOM   5721 H  HG2  . GLN A 1 360 ? 3.07757   -25.92556 3.21672   1.000 28.33885 ? 1819 GLN A HG2  1 
ATOM   5722 H  HG3  . GLN A 1 360 ? 3.89434   -25.06374 4.27293   1.000 28.33885 ? 1819 GLN A HG3  1 
ATOM   5723 H  HE21 . GLN A 1 360 ? 2.50025   -23.74171 5.78185   1.000 30.96653 ? 1819 GLN A HE21 1 
ATOM   5724 H  HE22 . GLN A 1 360 ? 1.24865   -24.36241 6.29859   1.000 30.96653 ? 1819 GLN A HE22 1 
ATOM   5725 N  N    . LEU A 1 361 ? 5.92047   -23.00646 3.09298   1.000 23.09226 ? 1820 LEU A N    1 
ATOM   5726 C  CA   . LEU A 1 361 ? 7.11418   -23.10896 3.91695   1.000 25.50308 ? 1820 LEU A CA   1 
ATOM   5727 C  C    . LEU A 1 361 ? 6.81508   -23.91667 5.18265   1.000 28.55608 ? 1820 LEU A C    1 
ATOM   5728 O  O    . LEU A 1 361 ? 5.70510   -23.86659 5.71614   1.000 28.90612 ? 1820 LEU A O    1 
ATOM   5729 C  CB   . LEU A 1 361 ? 7.58483   -21.71336 4.30613   1.000 25.56887 ? 1820 LEU A CB   1 
ATOM   5730 C  CG   . LEU A 1 361 ? 8.09367   -20.81085 3.18916   1.000 25.74258 ? 1820 LEU A CG   1 
ATOM   5731 C  CD1  . LEU A 1 361 ? 8.58409   -19.48630 3.78677   1.000 26.59794 ? 1820 LEU A CD1  1 
ATOM   5732 C  CD2  . LEU A 1 361 ? 9.19590   -21.44104 2.38085   1.000 25.03987 ? 1820 LEU A CD2  1 
ATOM   5733 H  H    . LEU A 1 361 ? 5.57441   -22.21963 3.06556   1.000 27.71351 ? 1820 LEU A H    1 
ATOM   5734 H  HA   . LEU A 1 361 ? 7.82081   -23.55791 3.42703   1.000 30.60649 ? 1820 LEU A HA   1 
ATOM   5735 H  HB2  . LEU A 1 361 ? 6.83902   -21.25334 4.72213   1.000 30.68545 ? 1820 LEU A HB2  1 
ATOM   5736 H  HB3  . LEU A 1 361 ? 8.31078   -21.81099 4.94202   1.000 30.68545 ? 1820 LEU A HB3  1 
ATOM   5737 H  HG   . LEU A 1 361 ? 7.35729   -20.65274 2.57789   1.000 30.89389 ? 1820 LEU A HG   1 
ATOM   5738 H  HD11 . LEU A 1 361 ? 8.90584   -18.91665 3.07062   1.000 31.92033 ? 1820 LEU A HD11 1 
ATOM   5739 H  HD12 . LEU A 1 361 ? 7.84681   -19.05510 4.24654   1.000 31.92033 ? 1820 LEU A HD12 1 
ATOM   5740 H  HD13 . LEU A 1 361 ? 9.30258   -19.66890 4.41234   1.000 31.92033 ? 1820 LEU A HD13 1 
ATOM   5741 H  HD21 . LEU A 1 361 ? 9.51904   -20.79707 1.73140   1.000 30.05064 ? 1820 LEU A HD21 1 
ATOM   5742 H  HD22 . LEU A 1 361 ? 9.91622   -21.69975 2.97676   1.000 30.05064 ? 1820 LEU A HD22 1 
ATOM   5743 H  HD23 . LEU A 1 361 ? 8.84624   -22.22295 1.92561   1.000 30.05064 ? 1820 LEU A HD23 1 
ATOM   5744 N  N    . PRO A 1 362 ? 7.79283   -24.68880 5.68070   1.000 31.65381 ? 1821 PRO A N    1 
ATOM   5745 C  CA   . PRO A 1 362 ? 7.54190   -25.48363 6.89334   1.000 34.17780 ? 1821 PRO A CA   1 
ATOM   5746 C  C    . PRO A 1 362 ? 7.10335   -24.62368 8.08209   1.000 36.46229 ? 1821 PRO A C    1 
ATOM   5747 O  O    . PRO A 1 362 ? 7.63330   -23.53279 8.29664   1.000 36.56756 ? 1821 PRO A O    1 
ATOM   5748 C  CB   . PRO A 1 362 ? 8.90623   -26.12438 7.18865   1.000 33.90672 ? 1821 PRO A CB   1 
ATOM   5749 C  CG   . PRO A 1 362 ? 9.62088   -26.12894 5.87741   1.000 33.45929 ? 1821 PRO A CG   1 
ATOM   5750 C  CD   . PRO A 1 362 ? 9.15921   -24.87674 5.16060   1.000 32.54340 ? 1821 PRO A CD   1 
ATOM   5751 O  OXT  . PRO A 1 362 ? 6.21746   -24.99465 8.86034   1.000 38.18354 ? 1821 PRO A OXT  1 
ATOM   5752 H  HA   . PRO A 1 362 ? 6.88024   -26.17078 6.71749   1.000 41.01616 ? 1821 PRO A HA   1 
ATOM   5753 H  HB2  . PRO A 1 362 ? 9.38573   -25.59357 7.84379   1.000 40.69086 ? 1821 PRO A HB2  1 
ATOM   5754 H  HB3  . PRO A 1 362 ? 8.78234   -27.02760 7.51992   1.000 40.69086 ? 1821 PRO A HB3  1 
ATOM   5755 H  HG2  . PRO A 1 362 ? 10.57929  -26.10807 6.02543   1.000 40.15395 ? 1821 PRO A HG2  1 
ATOM   5756 H  HG3  . PRO A 1 362 ? 9.38005   -26.92275 5.37465   1.000 40.15395 ? 1821 PRO A HG3  1 
ATOM   5757 H  HD2  . PRO A 1 362 ? 9.72330   -24.12021 5.38501   1.000 39.05487 ? 1821 PRO A HD2  1 
ATOM   5758 H  HD3  . PRO A 1 362 ? 9.14978   -25.01009 4.19985   1.000 39.05487 ? 1821 PRO A HD3  1 
HETATM 5759 C  C    . FMT B 2 .   ? -23.70907 -15.08265 -28.90124 1.000 35.03580 ? 1901 FMT A C    1 
HETATM 5760 O  O1   . FMT B 2 .   ? -23.45304 -14.40905 -27.88620 1.000 34.63049 ? 1901 FMT A O1   1 
HETATM 5761 O  O2   . FMT B 2 .   ? -24.16148 -14.59489 -29.95035 1.000 35.28057 ? 1901 FMT A O2   1 
HETATM 5762 H  H    . FMT B 2 .   ? -23.53282 -16.15912 -28.90087 1.000 42.04576 ? 1901 FMT A H    1 
HETATM 5763 H  HO2  . FMT B 2 .   ? -24.33605 -13.63227 -30.00774 1.000 42.33948 ? 1901 FMT A HO2  1 
HETATM 5764 C  C    . FMT C 2 .   ? -3.78797  -31.75154 -23.38292 1.000 28.86137 ? 1902 FMT A C    1 
HETATM 5765 O  O1   . FMT C 2 .   ? -4.11851  -31.41411 -24.52393 1.000 28.98507 ? 1902 FMT A O1   1 
HETATM 5766 O  O2   . FMT C 2 .   ? -3.86335  -32.92420 -22.96560 1.000 28.56924 ? 1902 FMT A O2   1 
HETATM 5767 H  H    . FMT C 2 .   ? -3.38638  -31.00029 -22.69904 1.000 34.63645 ? 1902 FMT A H    1 
HETATM 5768 H  HO2  . FMT C 2 .   ? -4.59738  -33.50288 -23.26010 1.000 34.28588 ? 1902 FMT A HO2  1 
HETATM 5769 C  C    . FMT D 2 .   ? -6.48886  -22.01956 13.07885  1.000 34.46205 ? 1903 FMT A C    1 
HETATM 5770 O  O1   . FMT D 2 .   ? -6.47084  -20.82048 12.81738  1.000 35.52533 ? 1903 FMT A O1   1 
HETATM 5771 O  O2   . FMT D 2 .   ? -7.52281  -22.65251 13.32545  1.000 33.30401 ? 1903 FMT A O2   1 
HETATM 5772 H  H    . FMT D 2 .   ? -5.55092  -22.57154 13.09522  1.000 41.35725 ? 1903 FMT A H    1 
HETATM 5773 H  HO2  . FMT D 2 .   ? -8.38968  -22.19543 13.32222  1.000 39.96761 ? 1903 FMT A HO2  1 
HETATM 5774 C  C    . FMT E 2 .   ? -5.84752  -14.96347 -3.91296  1.000 17.87848 ? 1904 FMT A C    1 
HETATM 5775 O  O1   . FMT E 2 .   ? -5.61220  -15.57487 -2.89094  1.000 17.15471 ? 1904 FMT A O1   1 
HETATM 5776 O  O2   . FMT E 2 .   ? -4.98676  -14.24370 -4.42030  1.000 19.85766 ? 1904 FMT A O2   1 
HETATM 5777 H  H    . FMT E 2 .   ? -6.82546  -15.02532 -4.38961  1.000 21.45697 ? 1904 FMT A H    1 
HETATM 5778 H  HO2  . FMT E 2 .   ? -4.05792  -14.29944 -4.11282  1.000 23.83199 ? 1904 FMT A HO2  1 
HETATM 5779 C  C    . FMT F 2 .   ? -25.62143 -28.24594 -30.15759 1.000 39.97060 ? 1905 FMT A C    1 
HETATM 5780 O  O1   . FMT F 2 .   ? -24.44234 -28.51748 -29.90372 1.000 40.05482 ? 1905 FMT A O1   1 
HETATM 5781 O  O2   . FMT F 2 .   ? -26.18866 -28.63341 -31.18229 1.000 40.35486 ? 1905 FMT A O2   1 
HETATM 5782 H  H    . FMT F 2 .   ? -26.18399 -27.57758 -29.50558 1.000 47.96752 ? 1905 FMT A H    1 
HETATM 5783 H  HO2  . FMT F 2 .   ? -25.71528 -29.21293 -31.81511 1.000 48.42863 ? 1905 FMT A HO2  1 
HETATM 5784 C  C    . FMT G 2 .   ? 0.40332   -26.86257 -23.15992 1.000 20.77356 ? 1906 FMT A C    1 
HETATM 5785 O  O1   . FMT G 2 .   ? 0.09202   -25.94628 -22.39949 1.000 18.06272 ? 1906 FMT A O1   1 
HETATM 5786 O  O2   . FMT G 2 .   ? -0.15164  -27.04862 -24.24331 1.000 21.67630 ? 1906 FMT A O2   1 
HETATM 5787 H  H    . FMT G 2 .   ? 1.17448   -27.57958 -22.86882 1.000 24.93107 ? 1906 FMT A H    1 
HETATM 5788 H  HO2  . FMT G 2 .   ? -0.86798  -26.44755 -24.53652 1.000 26.01436 ? 1906 FMT A HO2  1 
HETATM 5789 C  C    . FMT H 2 .   ? -0.67991  1.08179   -3.47457  1.000 27.21118 ? 1907 FMT A C    1 
HETATM 5790 O  O1   . FMT H 2 .   ? -0.98272  1.44033   -4.61087  1.000 28.27972 ? 1907 FMT A O1   1 
HETATM 5791 O  O2   . FMT H 2 .   ? 0.48611   0.83224   -3.18107  1.000 27.26908 ? 1907 FMT A O2   1 
HETATM 5792 H  H    . FMT H 2 .   ? -1.39414  1.19394   -2.66151  1.000 32.65621 ? 1907 FMT A H    1 
HETATM 5793 H  HO2  . FMT H 2 .   ? 1.18261   0.86552   -3.86967  1.000 32.72569 ? 1907 FMT A HO2  1 
HETATM 5794 C  C    . FMT I 2 .   ? -0.16505  -23.76439 -15.39365 0.646 16.65464 ? 1908 FMT A C    1 
HETATM 5795 O  O1   . FMT I 2 .   ? -0.31920  -24.38099 -16.45927 0.646 15.52557 ? 1908 FMT A O1   1 
HETATM 5796 O  O2   . FMT I 2 .   ? 0.33709   -24.28317 -14.37773 0.646 15.52294 ? 1908 FMT A O2   1 
HETATM 5797 H  H    . FMT I 2 .   ? -0.49406  -22.73489 -15.31906 0.646 19.98837 ? 1908 FMT A H    1 
HETATM 5798 H  HO2  . FMT I 2 .   ? 1.19375   -24.75491 -14.44091 0.646 18.63032 ? 1908 FMT A HO2  1 
HETATM 5799 C  C    . FMT J 2 .   ? -27.48904 -34.14156 4.50212   1.000 28.70873 ? 1909 FMT A C    1 
HETATM 5800 O  O1   . FMT J 2 .   ? -27.09362 -34.46837 3.37648   1.000 29.29037 ? 1909 FMT A O1   1 
HETATM 5801 O  O2   . FMT J 2 .   ? -27.31529 -33.00408 4.96907   1.000 29.22984 ? 1909 FMT A O2   1 
HETATM 5802 H  H    . FMT J 2 .   ? -28.08717 -34.83782 5.09186   1.000 34.45327 ? 1909 FMT A H    1 
HETATM 5803 H  HO2  . FMT J 2 .   ? -26.85392 -32.32167 4.43816   1.000 35.07860 ? 1909 FMT A HO2  1 
HETATM 5804 ZN ZN   . ZN  K 3 .   ? -20.60431 -14.07096 -6.15646  1.000 9.91437  ? 1910 ZN  A ZN   1 
HETATM 5805 ZN ZN   . ZN  L 3 .   ? -21.07325 -17.25950 -6.91243  1.000 9.71961  ? 1911 ZN  A ZN   1 
HETATM 5806 ZN ZN   . ZN  M 3 .   ? -15.25192 -16.48955 -8.03736  0.570 11.86196 ? 1912 ZN  A ZN   1 
HETATM 5807 ZN ZN   . ZN  N 3 .   ? -1.19380  -24.48133 -22.80687 0.721 11.82512 ? 1913 ZN  A ZN   1 
HETATM 5808 C  C1   . GOL O 4 .   ? -27.28104 -17.83098 -5.87933  0.696 21.51839 ? 1914 GOL A C1   1 
HETATM 5809 O  O1   . GOL O 4 .   ? -27.81470 -18.70522 -4.92840  0.696 24.16607 ? 1914 GOL A O1   1 
HETATM 5810 C  C2   . GOL O 4 .   ? -25.78262 -17.72960 -5.55902  0.696 22.26848 ? 1914 GOL A C2   1 
HETATM 5811 O  O2   . GOL O 4 .   ? -25.41427 -18.96375 -5.28811  0.696 22.25532 ? 1914 GOL A O2   1 
HETATM 5812 C  C3   . GOL O 4 .   ? -25.11852 -17.03161 -6.71506  0.696 21.71052 ? 1914 GOL A C3   1 
HETATM 5813 O  O3   . GOL O 4 .   ? -25.89762 -15.80541 -7.02462  0.696 24.00026 ? 1914 GOL A O3   1 
HETATM 5814 H  H11  . GOL O 4 .   ? -27.68230 -16.94843 -5.84791  0.696 25.82487 ? 1914 GOL A H11  1 
HETATM 5815 H  H12  . GOL O 4 .   ? -27.40010 -18.14479 -6.78941  0.696 25.82487 ? 1914 GOL A H12  1 
HETATM 5816 H  HO1  . GOL O 4 .   ? -28.61769 -18.43852 -4.75267  0.696 29.00208 ? 1914 GOL A HO1  1 
HETATM 5817 H  H2   . GOL O 4 .   ? -25.54560 -17.17198 -4.80153  0.696 26.72497 ? 1914 GOL A H2   1 
HETATM 5818 H  H31  . GOL O 4 .   ? -25.06960 -17.65000 -7.46078  0.696 26.05542 ? 1914 GOL A H31  1 
HETATM 5819 H  H32  . GOL O 4 .   ? -24.19717 -16.84670 -6.47459  0.696 26.05542 ? 1914 GOL A H32  1 
HETATM 5820 H  HO3  . GOL O 4 .   ? -25.35027 -15.18781 -7.11414  0.696 28.80311 ? 1914 GOL A HO3  1 
HETATM 5821 NA NA   . NA  P 5 .   ? -15.16279 -40.09177 -6.36377  1.000 25.83470 ? 1915 NA  A NA   1 
HETATM 5822 O  O    . HOH Q 6 .   ? 0.69570   -28.83639 -5.43664  1.000 23.50284 ? 2001 HOH A O    1 
HETATM 5823 O  O    . HOH Q 6 .   ? -23.03407 -14.82605 11.35178  1.000 30.84319 ? 2002 HOH A O    1 
HETATM 5824 O  O    . HOH Q 6 .   ? -25.83843 -14.31218 -8.78618  1.000 30.05889 ? 2003 HOH A O    1 
HETATM 5825 O  O    . HOH Q 6 .   ? -5.51658  -18.76437 13.26777  1.000 34.31992 ? 2004 HOH A O    1 
HETATM 5826 O  O    . HOH Q 6 .   ? -1.19309  -15.31022 -2.50974  0.824 28.97718 ? 2005 HOH A O    1 
HETATM 5827 O  O    . HOH Q 6 .   ? -12.95943 -27.48968 -35.52415 1.000 26.64006 ? 2006 HOH A O    1 
HETATM 5828 O  O    . HOH Q 6 .   ? -15.31798 -43.18377 -7.37780  1.000 22.68695 ? 2007 HOH A O    1 
HETATM 5829 O  O    . HOH Q 6 .   ? -24.16540 -14.67296 -5.84475  1.000 23.00015 ? 2008 HOH A O    1 
HETATM 5830 O  O    . HOH Q 6 .   ? -23.48521 -9.04978  3.73536   1.000 34.79367 ? 2009 HOH A O    1 
HETATM 5831 O  O    . HOH Q 6 .   ? -5.91886  -36.21540 -29.06309 1.000 34.72787 ? 2010 HOH A O    1 
HETATM 5832 O  O    . HOH Q 6 .   ? -14.01057 0.89859   -22.41225 1.000 30.39051 ? 2011 HOH A O    1 
HETATM 5833 O  O    . HOH Q 6 .   ? -4.70818  -42.74587 -18.54429 1.000 35.70693 ? 2012 HOH A O    1 
HETATM 5834 O  O    . HOH Q 6 .   ? -9.79641  -26.30412 11.26634  1.000 28.94823 ? 2013 HOH A O    1 
HETATM 5835 O  O    . HOH Q 6 .   ? -6.36097  -40.87112 -23.70720 1.000 42.44195 ? 2014 HOH A O    1 
HETATM 5836 O  O    . HOH Q 6 .   ? -31.56068 -19.21657 -34.67701 1.000 43.90528 ? 2015 HOH A O    1 
HETATM 5837 O  O    . HOH Q 6 .   ? -21.73493 -27.67413 10.29748  1.000 28.01127 ? 2016 HOH A O    1 
HETATM 5838 O  O    . HOH Q 6 .   ? -23.35945 -15.50918 -33.27683 1.000 33.04346 ? 2017 HOH A O    1 
HETATM 5839 O  O    . HOH Q 6 .   ? -16.90276 3.84593   -21.59818 1.000 38.67571 ? 2018 HOH A O    1 
HETATM 5840 O  O    . HOH Q 6 .   ? -39.33577 -13.72193 -17.84520 1.000 30.39051 ? 2019 HOH A O    1 
HETATM 5841 O  O    . HOH Q 6 .   ? -10.86020 -28.67991 12.70681  1.000 41.30760 ? 2020 HOH A O    1 
HETATM 5842 O  O    . HOH Q 6 .   ? -29.62262 -5.93486  -9.19800  1.000 37.87298 ? 2021 HOH A O    1 
HETATM 5843 O  O    . HOH Q 6 .   ? -1.46924  -16.20654 -0.85035  1.000 25.48465 ? 2022 HOH A O    1 
HETATM 5844 O  O    . HOH Q 6 .   ? -34.83214 -20.30958 -20.72827 1.000 17.58897 ? 2023 HOH A O    1 
HETATM 5845 O  O    . HOH Q 6 .   ? -27.20904 -34.00591 -24.03002 1.000 37.62822 ? 2024 HOH A O    1 
HETATM 5846 O  O    . HOH Q 6 .   ? -12.96954 -38.91628 1.62925   1.000 27.67439 ? 2025 HOH A O    1 
HETATM 5847 O  O    . HOH Q 6 .   ? -4.52241  -29.28193 -25.94560 1.000 32.58551 ? 2026 HOH A O    1 
HETATM 5848 O  O    . HOH Q 6 .   ? -16.98471 6.01211   -17.72232 1.000 34.18307 ? 2027 HOH A O    1 
HETATM 5849 O  O    . HOH Q 6 .   ? -37.94208 -24.39266 -26.20471 1.000 32.69341 ? 2028 HOH A O    1 
HETATM 5850 O  O    . HOH Q 6 .   ? -21.96762 -13.28868 -32.13414 1.000 26.60847 ? 2029 HOH A O    1 
HETATM 5851 O  O    . HOH Q 6 .   ? -23.78814 3.82321   -19.80596 1.000 39.96534 ? 2030 HOH A O    1 
HETATM 5852 O  O    . HOH Q 6 .   ? -22.93014 -13.70376 -11.37748 1.000 17.50738 ? 2031 HOH A O    1 
HETATM 5853 O  O    . HOH Q 6 .   ? -1.91159  -34.63311 -11.52659 1.000 27.72176 ? 2032 HOH A O    1 
HETATM 5854 O  O    . HOH Q 6 .   ? -40.40668 -22.52842 -4.75759  1.000 34.17254 ? 2033 HOH A O    1 
HETATM 5855 O  O    . HOH Q 6 .   ? -37.94516 -22.94322 -3.61883  1.000 34.46994 ? 2034 HOH A O    1 
HETATM 5856 O  O    . HOH Q 6 .   ? -1.25491  -15.11000 -23.46489 1.000 27.15854 ? 2035 HOH A O    1 
HETATM 5857 O  O    . HOH Q 6 .   ? -25.10643 -5.93210  -8.61359  1.000 13.37794 ? 2036 HOH A O    1 
HETATM 5858 O  O    . HOH Q 6 .   ? -35.27953 -29.29712 -12.92946 1.000 28.84295 ? 2037 HOH A O    1 
HETATM 5859 O  O    . HOH Q 6 .   ? -29.69642 -35.12576 -5.24113  1.000 29.09298 ? 2038 HOH A O    1 
HETATM 5860 O  O    . HOH Q 6 .   ? -5.77862  -6.05531  13.04039  1.000 26.01893 ? 2039 HOH A O    1 
HETATM 5861 O  O    . HOH Q 6 .   ? -21.75534 -14.87184 9.28805   1.000 26.69269 ? 2040 HOH A O    1 
HETATM 5862 O  O    . HOH Q 6 .   ? -22.02344 -30.77841 -26.99910 1.000 22.07109 ? 2041 HOH A O    1 
HETATM 5863 O  O    . HOH Q 6 .   ? -35.64792 -29.99277 -10.06988 1.000 27.35330 ? 2042 HOH A O    1 
HETATM 5864 O  O    . HOH Q 6 .   ? -37.37921 -25.11005 -21.68565 1.000 20.11296 ? 2043 HOH A O    1 
HETATM 5865 O  O    . HOH Q 6 .   ? -4.18362  -13.66365 -6.86777  1.000 17.67319 ? 2044 HOH A O    1 
HETATM 5866 O  O    . HOH Q 6 .   ? -3.03066  -7.06540  10.46793  1.000 26.15052 ? 2045 HOH A O    1 
HETATM 5867 O  O    . HOH Q 6 .   ? -38.29865 -19.38371 -23.09953 1.000 28.69293 ? 2046 HOH A O    1 
HETATM 5868 O  O    . HOH Q 6 .   ? -17.53544 -11.51017 14.20201  1.000 28.06128 ? 2047 HOH A O    1 
HETATM 5869 O  O    . HOH Q 6 .   ? -16.51926 -44.06268 -20.15881 1.000 21.82106 ? 2048 HOH A O    1 
HETATM 5870 O  O    . HOH Q 6 .   ? -9.77957  -8.28886  15.54334  1.000 25.32674 ? 2049 HOH A O    1 
HETATM 5871 O  O    . HOH Q 6 .   ? -15.08265 -45.52730 -18.40079 1.000 34.13832 ? 2050 HOH A O    1 
HETATM 5872 O  O    . HOH Q 6 .   ? -13.54504 -16.57228 15.60156  1.000 32.26968 ? 2051 HOH A O    1 
HETATM 5873 O  O    . HOH Q 6 .   ? -26.07296 -1.72920  -13.91387 1.000 22.40797 ? 2052 HOH A O    1 
HETATM 5874 O  O    . HOH Q 6 .   ? -7.18643  -10.42755 -26.23761 1.000 22.88434 ? 2053 HOH A O    1 
HETATM 5875 O  O    . HOH Q 6 .   ? -20.58334 -9.21516  -26.29245 1.000 26.78481 ? 2054 HOH A O    1 
HETATM 5876 O  O    . HOH Q 6 .   ? -12.01547 -41.84801 -10.54923 1.000 22.75012 ? 2055 HOH A O    1 
HETATM 5877 O  O    . HOH Q 6 .   ? -19.31191 3.01907   -6.73805  1.000 25.39780 ? 2056 HOH A O    1 
HETATM 5878 O  O    . HOH Q 6 .   ? -25.24076 -1.39277  -10.17862 1.000 34.27255 ? 2057 HOH A O    1 
HETATM 5879 O  O    . HOH Q 6 .   ? -11.60244 -37.81872 -3.90980  1.000 16.20723 ? 2058 HOH A O    1 
HETATM 5880 O  O    . HOH Q 6 .   ? -2.95696  -14.68924 -27.85389 1.000 33.19874 ? 2059 HOH A O    1 
HETATM 5881 O  O    . HOH Q 6 .   ? -24.96402 -35.68188 -6.59101  1.000 17.85479 ? 2060 HOH A O    1 
HETATM 5882 O  O    . HOH Q 6 .   ? -7.67849  -35.01083 -29.80621 1.000 47.18989 ? 2061 HOH A O    1 
HETATM 5883 O  O    . HOH Q 6 .   ? -4.41146  -15.06780 4.78480   1.000 16.03089 ? 2062 HOH A O    1 
HETATM 5884 O  O    . HOH Q 6 .   ? -1.81990  -9.75409  -10.64593 1.000 17.89690 ? 2063 HOH A O    1 
HETATM 5885 O  O    . HOH Q 6 .   ? -34.04953 -8.15653  -12.33074 1.000 35.88064 ? 2064 HOH A O    1 
HETATM 5886 O  O    . HOH Q 6 .   ? -21.16023 -9.83697  4.01014   1.000 22.71064 ? 2065 HOH A O    1 
HETATM 5887 O  O    . HOH Q 6 .   ? -15.23560 -23.53800 12.52578  1.000 25.65836 ? 2066 HOH A O    1 
HETATM 5888 O  O    . HOH Q 6 .   ? -29.58767 -33.62805 -15.34468 1.000 25.21620 ? 2067 HOH A O    1 
HETATM 5889 O  O    . HOH Q 6 .   ? -27.83859 1.01514   -19.86857 1.000 24.33188 ? 2068 HOH A O    1 
HETATM 5890 O  O    . HOH Q 6 .   ? -2.72719  -17.30406 -5.45882  1.000 28.25867 ? 2069 HOH A O    1 
HETATM 5891 O  O    . HOH Q 6 .   ? -22.33550 2.52449   -17.88708 1.000 25.66889 ? 2070 HOH A O    1 
HETATM 5892 O  O    . HOH Q 6 .   ? -30.88567 -26.94126 -18.10851 1.000 13.88590 ? 2071 HOH A O    1 
HETATM 5893 O  O    . HOH Q 6 .   ? -7.23214  -29.53510 -16.06208 1.000 12.23043 ? 2072 HOH A O    1 
HETATM 5894 O  O    . HOH Q 6 .   ? 2.29370   -8.27561  -6.74774  1.000 25.33990 ? 2073 HOH A O    1 
HETATM 5895 O  O    . HOH Q 6 .   ? -12.05666 -20.72559 -14.01330 1.000 10.43811 ? 2074 HOH A O    1 
HETATM 5896 O  O    . HOH Q 6 .   ? -25.10607 -31.69671 -24.13061 1.000 18.07324 ? 2075 HOH A O    1 
HETATM 5897 O  O    . HOH Q 6 .   ? -18.43373 -24.20407 -20.60126 1.000 13.37268 ? 2076 HOH A O    1 
HETATM 5898 O  O    . HOH Q 6 .   ? -32.41541 -9.84741  -25.58538 1.000 24.65824 ? 2077 HOH A O    1 
HETATM 5899 O  O    . HOH Q 6 .   ? -8.13819  -44.42111 -16.94907 1.000 31.11954 ? 2078 HOH A O    1 
HETATM 5900 O  O    . HOH Q 6 .   ? -22.42706 -19.33739 -19.56261 1.000 11.28032 ? 2079 HOH A O    1 
HETATM 5901 O  O    . HOH Q 6 .   ? -31.14382 -1.10312  -22.64196 1.000 39.46528 ? 2080 HOH A O    1 
HETATM 5902 O  O    . HOH Q 6 .   ? -8.03768  -3.26219  -25.90979 1.000 34.64102 ? 2081 HOH A O    1 
HETATM 5903 O  O    . HOH Q 6 .   ? -17.53023 -16.54490 -36.70810 1.000 33.40139 ? 2082 HOH A O    1 
HETATM 5904 O  O    . HOH Q 6 .   ? -9.84033  -7.04504  -26.34478 1.000 28.24551 ? 2083 HOH A O    1 
HETATM 5905 O  O    . HOH Q 6 .   ? -31.71825 -28.98768 -24.46081 1.000 26.80587 ? 2084 HOH A O    1 
HETATM 5906 O  O    . HOH Q 6 .   ? -12.41877 -48.22703 -19.86946 1.000 42.93675 ? 2085 HOH A O    1 
HETATM 5907 O  O    . HOH Q 6 .   ? -26.11419 -23.12031 -2.75041  1.000 13.78588 ? 2086 HOH A O    1 
HETATM 5908 O  O    . HOH Q 6 .   ? -25.05830 0.36011   -7.96653  1.000 41.51816 ? 2087 HOH A O    1 
HETATM 5909 O  O    . HOH Q 6 .   ? -34.28386 -7.58745  -24.41105 1.000 21.91844 ? 2088 HOH A O    1 
HETATM 5910 O  O    . HOH Q 6 .   ? -37.41974 -23.55252 -19.30440 1.000 17.47580 ? 2089 HOH A O    1 
HETATM 5911 O  O    . HOH Q 6 .   ? 1.78438   -33.58446 -1.32597  1.000 31.80120 ? 2090 HOH A O    1 
HETATM 5912 O  O    . HOH Q 6 .   ? -2.44919  -9.94291  -19.50298 1.000 27.78230 ? 2091 HOH A O    1 
HETATM 5913 O  O    . HOH Q 6 .   ? -40.83673 -19.45542 -5.61242  1.000 29.77991 ? 2092 HOH A O    1 
HETATM 5914 O  O    . HOH Q 6 .   ? -17.22645 -9.51672  -7.20846  1.000 11.34085 ? 2093 HOH A O    1 
HETATM 5915 O  O    . HOH Q 6 .   ? -6.94999  -11.61762 13.93496  1.000 29.12720 ? 2094 HOH A O    1 
HETATM 5916 O  O    . HOH Q 6 .   ? -6.65629  -20.38977 9.93478   1.000 22.15268 ? 2095 HOH A O    1 
HETATM 5917 O  O    . HOH Q 6 .   ? -24.84215 -7.49656  -4.64924  1.000 23.26860 ? 2096 HOH A O    1 
HETATM 5918 O  O    . HOH Q 6 .   ? -25.07869 -29.41732 -22.66086 1.000 16.53884 ? 2097 HOH A O    1 
HETATM 5919 O  O    . HOH Q 6 .   ? -32.51740 -11.60242 -6.50626  1.000 32.99345 ? 2098 HOH A O    1 
HETATM 5920 O  O    . HOH Q 6 .   ? -2.93783  -38.55434 -9.48226  1.000 35.04633 ? 2099 HOH A O    1 
HETATM 5921 O  O    . HOH Q 6 .   ? -20.35669 -15.82965 -35.18930 1.000 37.54663 ? 2100 HOH A O    1 
HETATM 5922 O  O    . HOH Q 6 .   ? -13.29735 -44.85554 -21.65227 1.000 23.23702 ? 2101 HOH A O    1 
HETATM 5923 O  O    . HOH Q 6 .   ? -22.82598 0.93895   -15.09790 1.000 28.95612 ? 2102 HOH A O    1 
HETATM 5924 O  O    . HOH Q 6 .   ? -20.40055 1.35195   -11.85248 1.000 20.39720 ? 2103 HOH A O    1 
HETATM 5925 O  O    . HOH Q 6 .   ? -35.96735 -21.34993 -27.95988 1.000 27.85862 ? 2104 HOH A O    1 
HETATM 5926 O  O    . HOH Q 6 .   ? -28.88900 -30.48843 4.19716   1.000 25.10566 ? 2105 HOH A O    1 
HETATM 5927 O  O    . HOH Q 6 .   ? 0.98145   -30.09253 -9.12121  1.000 31.59855 ? 2106 HOH A O    1 
HETATM 5928 O  O    . HOH Q 6 .   ? -12.55940 -30.98164 0.26526   1.000 35.59113 ? 2107 HOH A O    1 
HETATM 5929 O  O    . HOH Q 6 .   ? -2.30575  -10.77584 -13.14807 1.000 17.69951 ? 2108 HOH A O    1 
HETATM 5930 O  O    . HOH Q 6 .   ? -13.99690 -12.42380 11.41261  1.000 15.60452 ? 2109 HOH A O    1 
HETATM 5931 O  O    . HOH Q 6 .   ? -16.79983 1.31365   -22.23362 1.000 22.11583 ? 2110 HOH A O    1 
HETATM 5932 O  O    . HOH Q 6 .   ? -5.43952  -31.39839 -19.58752 1.000 14.08066 ? 2111 HOH A O    1 
HETATM 5933 O  O    . HOH Q 6 .   ? -9.67548  -9.56146  -26.38656 1.000 26.42687 ? 2112 HOH A O    1 
HETATM 5934 O  O    . HOH Q 6 .   ? -18.37714 -14.41599 3.78435   1.000 15.66506 ? 2113 HOH A O    1 
HETATM 5935 O  O    . HOH Q 6 .   ? -29.83907 -24.60442 -18.91467 1.000 14.22015 ? 2114 HOH A O    1 
HETATM 5936 O  O    . HOH Q 6 .   ? -0.59149  -7.11583  -0.53419  1.000 16.79414 ? 2115 HOH A O    1 
HETATM 5937 O  O    . HOH Q 6 .   ? -41.96044 -11.52804 -8.80612  1.000 26.38739 ? 2116 HOH A O    1 
HETATM 5938 O  O    . HOH Q 6 .   ? -26.74127 -20.97269 -19.37562 1.000 12.09094 ? 2117 HOH A O    1 
HETATM 5939 O  O    . HOH Q 6 .   ? -29.39313 -11.96306 -25.89604 1.000 25.27147 ? 2118 HOH A O    1 
HETATM 5940 O  O    . HOH Q 6 .   ? -2.47320  -33.34605 -18.47171 1.000 20.29193 ? 2119 HOH A O    1 
HETATM 5941 O  O    . HOH Q 6 .   ? -5.27506  -11.86767 -28.85777 1.000 24.80036 ? 2120 HOH A O    1 
HETATM 5942 O  O    . HOH Q 6 .   ? -39.01320 -24.98468 -7.92894  1.000 21.61314 ? 2121 HOH A O    1 
HETATM 5943 O  O    . HOH Q 6 .   ? 0.55578   -3.02572  -0.83251  1.000 27.05853 ? 2122 HOH A O    1 
HETATM 5944 O  O    . HOH Q 6 .   ? -18.21696 -11.31459 -14.19929 1.000 9.59064  ? 2123 HOH A O    1 
HETATM 5945 O  O    . HOH Q 6 .   ? -21.60056 -25.46251 -4.31722  1.000 12.24622 ? 2124 HOH A O    1 
HETATM 5946 O  O    . HOH Q 6 .   ? -37.06639 -14.73790 -21.39880 1.000 21.93160 ? 2125 HOH A O    1 
HETATM 5947 O  O    . HOH Q 6 .   ? -3.05329  -27.51043 0.43044   1.000 21.22888 ? 2126 HOH A O    1 
HETATM 5948 O  O    . HOH Q 6 .   ? -2.54848  -13.52733 -15.52485 1.000 18.34959 ? 2127 HOH A O    1 
HETATM 5949 O  O    . HOH Q 6 .   ? -0.02631  -7.38100  -10.15544 1.000 32.30652 ? 2128 HOH A O    1 
HETATM 5950 O  O    . HOH Q 6 .   ? -28.46554 -35.64595 -10.73966 1.000 19.96820 ? 2129 HOH A O    1 
HETATM 5951 O  O    . HOH Q 6 .   ? -19.09029 0.77410   -14.23886 1.000 12.33571 ? 2130 HOH A O    1 
HETATM 5952 O  O    . HOH Q 6 .   ? -9.11700  -9.84158  -34.37855 1.000 35.44374 ? 2131 HOH A O    1 
HETATM 5953 O  O    . HOH Q 6 .   ? 1.36200   -12.59918 3.62643   1.000 33.29612 ? 2132 HOH A O    1 
HETATM 5954 O  O    . HOH Q 6 .   ? -27.47661 -34.93636 -0.93669  1.000 28.91664 ? 2133 HOH A O    1 
HETATM 5955 O  O    . HOH Q 6 .   ? -21.81381 -15.45149 -6.90792  1.000 9.29061  ? 2134 HOH A O    1 
HETATM 5956 O  O    . HOH Q 6 .   ? -26.22061 -32.97046 7.51539   1.000 32.76184 ? 2135 HOH A O    1 
HETATM 5957 O  O    . HOH Q 6 .   ? -2.15594  -13.27578 7.07795   1.000 28.19551 ? 2136 HOH A O    1 
HETATM 5958 O  O    . HOH Q 6 .   ? -32.84558 -30.15986 -16.57819 1.000 26.96115 ? 2137 HOH A O    1 
HETATM 5959 O  O    . HOH Q 6 .   ? -26.59785 -7.11303  -24.82307 1.000 29.92466 ? 2138 HOH A O    1 
HETATM 5960 O  O    . HOH Q 6 .   ? -13.42935 -31.38417 7.75555   1.000 26.80323 ? 2139 HOH A O    1 
HETATM 5961 O  O    . HOH Q 6 .   ? -22.69388 -4.92180  -13.82064 1.000 16.31250 ? 2140 HOH A O    1 
HETATM 5962 O  O    . HOH Q 6 .   ? -15.94695 -21.73810 -32.98049 1.000 21.67893 ? 2141 HOH A O    1 
HETATM 5963 O  O    . HOH Q 6 .   ? -19.62440 -45.75680 -19.41561 1.000 41.01546 ? 2142 HOH A O    1 
HETATM 5964 O  O    . HOH Q 6 .   ? -3.73177  -7.78017  -2.74827  1.000 15.22816 ? 2143 HOH A O    1 
HETATM 5965 O  O    . HOH Q 6 .   ? -8.03646  -7.64370  13.39571  1.000 29.07719 ? 2144 HOH A O    1 
HETATM 5966 O  O    . HOH Q 6 .   ? -43.06158 -18.97354 -10.42825 1.000 20.20771 ? 2145 HOH A O    1 
HETATM 5967 O  O    . HOH Q 6 .   ? -4.62209  -26.75458 6.66957   1.000 23.54495 ? 2146 HOH A O    1 
HETATM 5968 O  O    . HOH Q 6 .   ? -2.93364  -11.81641 -26.14398 1.000 34.73050 ? 2147 HOH A O    1 
HETATM 5969 O  O    . HOH Q 6 .   ? -18.80752 -44.14483 -9.43806  1.000 22.63694 ? 2148 HOH A O    1 
HETATM 5970 O  O    . HOH Q 6 .   ? -25.72717 -20.90476 2.69954   1.000 23.62917 ? 2149 HOH A O    1 
HETATM 5971 O  O    . HOH Q 6 .   ? -18.40036 -40.53895 -0.89435  1.000 15.54662 ? 2150 HOH A O    1 
HETATM 5972 O  O    . HOH Q 6 .   ? -21.25646 -42.97650 -5.77736  1.000 25.43991 ? 2151 HOH A O    1 
HETATM 5973 O  O    . HOH Q 6 .   ? -18.00905 -37.14880 -31.63208 1.000 33.21190 ? 2152 HOH A O    1 
HETATM 5974 O  O    . HOH Q 6 .   ? -6.11177  -29.49061 5.58561   1.000 25.19515 ? 2153 HOH A O    1 
HETATM 5975 O  O    . HOH Q 6 .   ? -0.87638  -0.34711  -1.05148  1.000 31.20376 ? 2154 HOH A O    1 
HETATM 5976 O  O    . HOH Q 6 .   ? -21.10014 -27.56160 -26.60759 1.000 29.89834 ? 2155 HOH A O    1 
HETATM 5977 O  O    . HOH Q 6 .   ? -2.69123  -33.44486 -1.08227  1.000 21.78947 ? 2156 HOH A O    1 
HETATM 5978 O  O    . HOH Q 6 .   ? -22.87357 -27.71076 -23.43823 1.000 21.19203 ? 2157 HOH A O    1 
HETATM 5979 O  O    . HOH Q 6 .   ? -21.47523 -27.98541 -3.38001  1.000 18.25221 ? 2158 HOH A O    1 
HETATM 5980 O  O    . HOH Q 6 .   ? -11.24385 -29.58487 -1.96161  1.000 15.06498 ? 2159 HOH A O    1 
HETATM 5981 O  O    . HOH Q 6 .   ? -23.41419 -7.42536  -18.18080 1.000 11.63299 ? 2160 HOH A O    1 
HETATM 5982 O  O    . HOH Q 6 .   ? -39.49833 -17.13631 -6.23058  1.000 25.57414 ? 2161 HOH A O    1 
HETATM 5983 O  O    . HOH Q 6 .   ? -1.72903  -28.36408 -19.67983 1.000 29.72464 ? 2162 HOH A O    1 
HETATM 5984 O  O    . HOH Q 6 .   ? -2.12114  -15.95450 8.15915   1.000 25.06881 ? 2163 HOH A O    1 
HETATM 5985 O  O    . HOH Q 6 .   ? -32.60683 -16.69689 -32.24486 1.000 37.37292 ? 2164 HOH A O    1 
HETATM 5986 O  O    . HOH Q 6 .   ? -14.97194 -11.61579 15.35743  1.000 33.00924 ? 2165 HOH A O    1 
HETATM 5987 O  O    . HOH Q 6 .   ? -29.04710 -4.89116  -14.48555 1.000 23.66075 ? 2166 HOH A O    1 
HETATM 5988 O  O    . HOH Q 6 .   ? -18.99314 -13.14010 -29.73499 1.000 22.70011 ? 2167 HOH A O    1 
HETATM 5989 O  O    . HOH Q 6 .   ? -5.17046  -28.74001 -14.39491 1.000 13.41215 ? 2168 HOH A O    1 
HETATM 5990 O  O    . HOH Q 6 .   ? -33.91629 -4.21665  -21.92414 1.000 22.46061 ? 2169 HOH A O    1 
HETATM 5991 O  O    . HOH Q 6 .   ? -30.53646 -19.76549 -12.04999 1.000 12.19885 ? 2170 HOH A O    1 
HETATM 5992 O  O    . HOH Q 6 .   ? -25.35782 -25.41066 -17.42988 1.000 11.46718 ? 2171 HOH A O    1 
HETATM 5993 O  O    . HOH Q 6 .   ? -2.41916  -2.14172  -15.45287 1.000 18.07324 ? 2172 HOH A O    1 
HETATM 5994 O  O    . HOH Q 6 .   ? -29.44928 -7.99420  -13.73663 1.000 15.35712 ? 2173 HOH A O    1 
HETATM 5995 O  O    . HOH Q 6 .   ? -23.07206 -11.69844 10.49841  1.000 35.27793 ? 2174 HOH A O    1 
HETATM 5996 O  O    . HOH Q 6 .   ? -9.39370  -19.64318 10.33501  1.000 17.62319 ? 2175 HOH A O    1 
HETATM 5997 O  O    . HOH Q 6 .   ? -23.51936 -18.81379 -14.97703 1.000 10.78552 ? 2176 HOH A O    1 
HETATM 5998 O  O    . HOH Q 6 .   ? -7.29939  1.93140   -14.75607 1.000 18.78122 ? 2177 HOH A O    1 
HETATM 5999 O  O    . HOH Q 6 .   ? -3.31973  -9.28299  -15.92625 1.000 22.35007 ? 2178 HOH A O    1 
HETATM 6000 O  O    . HOH Q 6 .   ? -32.50304 -27.73060 2.60652   1.000 31.50906 ? 2179 HOH A O    1 
HETATM 6001 O  O    . HOH Q 6 .   ? -34.74453 -17.45045 -21.40921 1.000 26.75849 ? 2180 HOH A O    1 
HETATM 6002 O  O    . HOH Q 6 .   ? -13.77913 -17.88968 -7.88323  1.000 11.30401 ? 2181 HOH A O    1 
HETATM 6003 O  O    . HOH Q 6 .   ? -17.90293 -25.70572 -0.94529  1.000 13.58060 ? 2182 HOH A O    1 
HETATM 6004 O  O    . HOH Q 6 .   ? 4.34551   -20.66669 3.09962   1.000 29.25616 ? 2183 HOH A O    1 
HETATM 6005 O  O    . HOH Q 6 .   ? -9.31576  -32.09048 0.36434   1.000 19.25496 ? 2184 HOH A O    1 
HETATM 6006 O  O    . HOH Q 6 .   ? -20.89214 -28.07889 13.37466  1.000 42.78147 ? 2185 HOH A O    1 
HETATM 6007 O  O    . HOH Q 6 .   ? -22.67365 -25.20794 8.62934   1.000 18.53119 ? 2186 HOH A O    1 
HETATM 6008 O  O    . HOH Q 6 .   ? -15.12481 -14.82351 12.08562  1.000 14.53597 ? 2187 HOH A O    1 
HETATM 6009 O  O    . HOH Q 6 .   ? -36.68033 -6.85249  -16.80549 1.000 24.98723 ? 2188 HOH A O    1 
HETATM 6010 O  O    . HOH Q 6 .   ? -26.33317 -41.09977 -13.95323 1.000 33.38297 ? 2189 HOH A O    1 
HETATM 6011 O  O    . HOH Q 6 .   ? -15.80339 -41.26870 -0.70354  1.000 23.70023 ? 2190 HOH A O    1 
HETATM 6012 O  O    . HOH Q 6 .   ? -8.94298  -37.45301 -4.50999  1.000 17.71004 ? 2191 HOH A O    1 
HETATM 6013 O  O    . HOH Q 6 .   ? -22.80304 -43.90378 -8.94076  1.000 28.66135 ? 2192 HOH A O    1 
HETATM 6014 O  O    . HOH Q 6 .   ? -23.82559 -37.10680 -3.48912  1.000 17.53107 ? 2193 HOH A O    1 
HETATM 6015 O  O    . HOH Q 6 .   ? -9.69790  -43.41531 -14.38032 1.000 24.51875 ? 2194 HOH A O    1 
HETATM 6016 O  O    . HOH Q 6 .   ? -0.29124  -12.28547 5.26733   1.000 32.76447 ? 2195 HOH A O    1 
HETATM 6017 O  O    . HOH Q 6 .   ? -13.65896 -20.57816 -32.52786 1.000 31.04585 ? 2196 HOH A O    1 
HETATM 6018 O  O    . HOH Q 6 .   ? -2.15310  2.81098   -11.09387 1.000 14.74389 ? 2197 HOH A O    1 
HETATM 6019 O  O    . HOH Q 6 .   ? -31.28514 -13.95809 -27.22505 1.000 34.31992 ? 2198 HOH A O    1 
HETATM 6020 O  O    . HOH Q 6 .   ? -33.68200 -20.80524 -29.14954 1.000 23.97658 ? 2199 HOH A O    1 
HETATM 6021 O  O    . HOH Q 6 .   ? -6.76792  -5.44648  -22.87921 1.000 24.81615 ? 2200 HOH A O    1 
HETATM 6022 O  O    . HOH Q 6 .   ? -21.37480 -13.55559 -29.63823 1.000 32.85133 ? 2201 HOH A O    1 
HETATM 6023 O  O    . HOH Q 6 .   ? -18.18807 -7.58794  -9.25137  1.000 14.16751 ? 2202 HOH A O    1 
HETATM 6024 O  O    . HOH Q 6 .   ? -23.41602 -2.28945  -13.97886 1.000 18.41275 ? 2203 HOH A O    1 
HETATM 6025 O  O    . HOH Q 6 .   ? -19.03717 -6.15158  5.98484   0.782 31.05637 ? 2204 HOH A O    1 
HETATM 6026 O  O    . HOH Q 6 .   ? -27.13426 -14.23214 -31.54579 1.000 28.24814 ? 2205 HOH A O    1 
HETATM 6027 O  O    . HOH Q 6 .   ? -3.12762  -16.99557 -2.91532  1.000 22.88961 ? 2206 HOH A O    1 
HETATM 6028 O  O    . HOH Q 6 .   ? -2.71051  -28.22870 -24.75370 1.000 26.61111 ? 2207 HOH A O    1 
HETATM 6029 O  O    . HOH Q 6 .   ? 1.81094   -20.11236 5.18372   1.000 32.92765 ? 2208 HOH A O    1 
HETATM 6030 O  O    . HOH Q 6 .   ? -7.25753  -23.46222 0.60662   1.000 12.75155 ? 2209 HOH A O    1 
HETATM 6031 O  O    . HOH Q 6 .   ? -2.61791  -19.41498 -3.13109  1.000 33.51456 ? 2210 HOH A O    1 
HETATM 6032 O  O    . HOH Q 6 .   ? -3.70740  -13.79817 -22.71095 1.000 22.38428 ? 2211 HOH A O    1 
HETATM 6033 O  O    . HOH Q 6 .   ? -19.47493 -7.34422  4.33402   1.000 27.41120 ? 2212 HOH A O    1 
HETATM 6034 O  O    . HOH Q 6 .   ? -6.90183  -17.70867 -32.10429 1.000 21.39469 ? 2213 HOH A O    1 
HETATM 6035 O  O    . HOH Q 6 .   ? -34.27746 -29.52842 -2.12044  1.000 27.47173 ? 2214 HOH A O    1 
HETATM 6036 O  O    . HOH Q 6 .   ? 2.61111   -0.27164  -4.76935  1.000 33.99357 ? 2215 HOH A O    1 
HETATM 6037 O  O    . HOH Q 6 .   ? -24.89749 -16.35271 -11.95979 1.000 11.68826 ? 2216 HOH A O    1 
HETATM 6038 O  O    . HOH Q 6 .   ? -5.91266  -29.76798 -31.98145 1.000 27.60596 ? 2217 HOH A O    1 
HETATM 6039 O  O    . HOH Q 6 .   ? -21.69250 -32.51863 9.03414   1.000 23.49757 ? 2218 HOH A O    1 
HETATM 6040 O  O    . HOH Q 6 .   ? -31.91899 -30.72466 -1.16774  1.000 22.14741 ? 2219 HOH A O    1 
HETATM 6041 O  O    . HOH Q 6 .   ? -38.77558 -21.29893 -26.15291 1.000 27.06905 ? 2220 HOH A O    1 
HETATM 6042 O  O    . HOH Q 6 .   ? 0.03781   -18.26961 7.34844   1.000 28.49554 ? 2221 HOH A O    1 
HETATM 6043 O  O    . HOH Q 6 .   ? -34.47537 -20.54967 -3.43409  1.000 30.97215 ? 2222 HOH A O    1 
HETATM 6044 O  O    . HOH Q 6 .   ? -20.84606 -2.24578  -3.27050  1.000 23.87130 ? 2223 HOH A O    1 
HETATM 6045 O  O    . HOH Q 6 .   ? -20.91626 -6.19654  -17.94072 1.000 12.31729 ? 2224 HOH A O    1 
HETATM 6046 O  O    . HOH Q 6 .   ? -1.13403  -37.06257 -19.14734 1.000 22.83170 ? 2225 HOH A O    1 
HETATM 6047 O  O    . HOH Q 6 .   ? -38.58556 -12.80418 -15.40419 1.000 20.73145 ? 2226 HOH A O    1 
HETATM 6048 O  O    . HOH Q 6 .   ? -25.79965 -28.55736 -27.36201 1.000 34.90157 ? 2227 HOH A O    1 
HETATM 6049 O  O    . HOH Q 6 .   ? -2.98303  -24.01483 9.43425   1.000 39.74426 ? 2228 HOH A O    1 
HETATM 6050 O  O    . HOH Q 6 .   ? -7.47260  2.84113   -18.74143 1.000 30.30365 ? 2229 HOH A O    1 
HETATM 6051 O  O    . HOH Q 6 .   ? -14.40072 -8.32511  15.84563  1.000 34.31729 ? 2230 HOH A O    1 
HETATM 6052 O  O    . HOH Q 6 .   ? -23.25868 -17.59098 -17.44687 1.000 12.05673 ? 2231 HOH A O    1 
HETATM 6053 O  O    . HOH Q 6 .   ? -27.72934 -26.18562 -35.43493 1.000 51.06667 ? 2232 HOH A O    1 
HETATM 6054 O  O    . HOH Q 6 .   ? -22.91952 -0.15872  -11.90399 1.000 21.71315 ? 2233 HOH A O    1 
HETATM 6055 O  O    . HOH Q 6 .   ? -16.46954 -15.56477 -19.00333 1.000 28.32710 ? 2234 HOH A O    1 
HETATM 6056 O  O    . HOH Q 6 .   ? 1.91024   -30.54612 -4.36336  1.000 26.60584 ? 2235 HOH A O    1 
HETATM 6057 O  O    . HOH Q 6 .   ? -38.90848 -29.43078 -20.98746 1.000 37.65453 ? 2236 HOH A O    1 
HETATM 6058 O  O    . HOH Q 6 .   ? -9.17869  -15.72383 -33.01780 1.000 27.01642 ? 2237 HOH A O    1 
HETATM 6059 O  O    . HOH Q 6 .   ? -23.91987 -11.67908 -26.98341 1.000 31.91174 ? 2238 HOH A O    1 
HETATM 6060 O  O    . HOH Q 6 .   ? -4.42312  -36.89758 -12.80374 1.000 25.93471 ? 2239 HOH A O    1 
HETATM 6061 O  O    . HOH Q 6 .   ? -14.57599 -26.19986 12.32917  1.000 25.16620 ? 2240 HOH A O    1 
HETATM 6062 O  O    . HOH Q 6 .   ? -6.26025  -3.24617  -20.60109 1.000 21.01307 ? 2241 HOH A O    1 
HETATM 6063 O  O    . HOH Q 6 .   ? -2.86411  -4.62076  9.31593   1.000 20.38141 ? 2242 HOH A O    1 
HETATM 6064 O  O    . HOH Q 6 .   ? -22.73399 -25.79593 -38.66365 1.000 33.31980 ? 2243 HOH A O    1 
HETATM 6065 O  O    . HOH Q 6 .   ? -17.10243 -14.32562 16.78332  1.000 41.00230 ? 2244 HOH A O    1 
HETATM 6066 O  O    . HOH Q 6 .   ? -20.72702 -15.49607 -28.25027 1.000 26.18474 ? 2245 HOH A O    1 
HETATM 6067 O  O    . HOH Q 6 .   ? -3.29418  -37.73860 -23.57080 1.000 34.44626 ? 2246 HOH A O    1 
HETATM 6068 O  O    . HOH Q 6 .   ? -3.91386  -11.06796 -22.43327 1.000 27.38488 ? 2247 HOH A O    1 
HETATM 6069 O  O    . HOH Q 6 .   ? -24.19823 -40.66011 -5.98685  1.000 31.15112 ? 2248 HOH A O    1 
HETATM 6070 O  O    . HOH Q 6 .   ? -16.08770 -3.92102  14.11698  1.000 18.83386 ? 2249 HOH A O    1 
HETATM 6071 O  O    . HOH Q 6 .   ? -9.86242  -17.55714 8.61074   1.000 16.43357 ? 2250 HOH A O    1 
HETATM 6072 O  O    . HOH Q 6 .   ? 0.58228   -27.26939 -19.23634 1.000 18.90755 ? 2251 HOH A O    1 
HETATM 6073 O  O    . HOH Q 6 .   ? -4.29939  -30.57080 0.69032   1.000 36.18331 ? 2252 HOH A O    1 
HETATM 6074 O  O    . HOH Q 6 .   ? -29.70569 -24.71112 -33.34032 1.000 27.21644 ? 2253 HOH A O    1 
HETATM 6075 O  O    . HOH Q 6 .   ? -10.81404 -18.00327 16.76008  1.000 35.35952 ? 2254 HOH A O    1 
HETATM 6076 O  O    . HOH Q 6 .   ? -23.11330 -3.15203  -5.70725  1.000 34.65681 ? 2255 HOH A O    1 
HETATM 6077 O  O    . HOH Q 6 .   ? -35.74964 -24.12297 -27.28458 1.000 23.76340 ? 2256 HOH A O    1 
HETATM 6078 O  O    . HOH Q 6 .   ? -1.23443  -26.21019 1.95306   1.000 23.94236 ? 2257 HOH A O    1 
HETATM 6079 O  O    . HOH Q 6 .   ? -10.41579 -34.21553 -35.95084 1.000 35.85432 ? 2258 HOH A O    1 
HETATM 6080 O  O    . HOH Q 6 .   ? -4.89544  -30.83751 -16.89144 1.000 12.69101 ? 2259 HOH A O    1 
HETATM 6081 O  O    . HOH Q 6 .   ? -30.37982 -34.85934 -19.63709 1.000 35.29636 ? 2260 HOH A O    1 
HETATM 6082 O  O    . HOH Q 6 .   ? -15.47707 -6.33434  -8.79576  1.000 27.49805 ? 2261 HOH A O    1 
HETATM 6083 O  O    . HOH Q 6 .   ? -26.03396 -38.39178 -20.50373 1.000 19.98926 ? 2262 HOH A O    1 
HETATM 6084 O  O    . HOH Q 6 .   ? -15.08525 -36.38780 4.52125   1.000 23.75287 ? 2263 HOH A O    1 
HETATM 6085 O  O    . HOH Q 6 .   ? -26.55703 0.11997   -22.06547 1.000 26.34265 ? 2264 HOH A O    1 
HETATM 6086 O  O    . HOH Q 6 .   ? -37.07262 -25.22709 -14.08305 1.000 23.97921 ? 2265 HOH A O    1 
HETATM 6087 O  O    . HOH Q 6 .   ? -17.38300 -15.54491 -12.02032 1.000 14.57808 ? 2266 HOH A O    1 
HETATM 6088 O  O    . HOH Q 6 .   ? -27.09660 -36.39023 -13.07790 1.000 22.76064 ? 2267 HOH A O    1 
HETATM 6089 O  O    . HOH Q 6 .   ? -15.65329 -42.00823 -5.39063  1.000 23.83709 ? 2268 HOH A O    1 
HETATM 6090 O  O    . HOH Q 6 .   ? -0.39906  -13.66008 -0.76933  1.000 16.68886 ? 2269 HOH A O    1 
HETATM 6091 O  O    . HOH Q 6 .   ? -21.51246 -3.64157  -25.42426 1.000 30.59316 ? 2270 HOH A O    1 
HETATM 6092 O  O    . HOH Q 6 .   ? -25.04239 -19.78504 -35.12837 1.000 29.91676 ? 2271 HOH A O    1 
HETATM 6093 O  O    . HOH Q 6 .   ? -27.79451 -21.15597 -35.46928 1.000 32.62235 ? 2272 HOH A O    1 
HETATM 6094 O  O    . HOH Q 6 .   ? -24.04561 -24.10106 -4.33252  1.000 11.55404 ? 2273 HOH A O    1 
HETATM 6095 O  O    . HOH Q 6 .   ? -4.05449  -18.76196 -30.17959 1.000 15.88087 ? 2274 HOH A O    1 
HETATM 6096 O  O    . HOH Q 6 .   ? -13.39471 -41.69566 -7.60316  1.000 25.39254 ? 2275 HOH A O    1 
HETATM 6097 O  O    . HOH Q 6 .   ? -2.84819  -14.86878 12.86937  1.000 38.89416 ? 2276 HOH A O    1 
HETATM 6098 O  O    . HOH Q 6 .   ? -12.29128 -7.62665  -28.31670 1.000 29.30353 ? 2277 HOH A O    1 
HETATM 6099 O  O    . HOH Q 6 .   ? -16.86237 -20.85588 15.60839  1.000 39.80479 ? 2278 HOH A O    1 
HETATM 6100 O  O    . HOH Q 6 .   ? -4.52538  -12.20678 -17.70844 1.000 34.13043 ? 2279 HOH A O    1 
HETATM 6101 O  O    . HOH Q 6 .   ? -5.25420  -41.18106 -16.18021 1.000 33.73828 ? 2280 HOH A O    1 
HETATM 6102 O  O    . HOH Q 6 .   ? -20.95607 -4.14525  12.54496  1.000 35.43585 ? 2281 HOH A O    1 
HETATM 6103 O  O    . HOH Q 6 .   ? -11.89634 1.00654   -20.58632 1.000 36.92813 ? 2282 HOH A O    1 
HETATM 6104 O  O    . HOH Q 6 .   ? -24.30065 -42.02531 -15.63175 1.000 42.73146 ? 2283 HOH A O    1 
HETATM 6105 O  O    . HOH Q 6 .   ? -21.97838 -32.29584 -29.86286 1.000 39.62846 ? 2284 HOH A O    1 
HETATM 6106 O  O    . HOH Q 6 .   ? -27.62536 -41.59577 -19.87991 1.000 47.14515 ? 2285 HOH A O    1 
HETATM 6107 O  O    . HOH Q 6 .   ? -39.65351 -24.86112 -12.44063 1.000 20.27877 ? 2286 HOH A O    1 
HETATM 6108 O  O    . HOH Q 6 .   ? -14.90816 -7.33171  -28.77805 1.000 26.72164 ? 2287 HOH A O    1 
HETATM 6109 O  O    . HOH Q 6 .   ? -7.33449  -41.70731 -12.44879 1.000 27.36383 ? 2288 HOH A O    1 
HETATM 6110 O  O    . HOH Q 6 .   ? -15.19247 -14.44436 14.87222  1.000 27.75861 ? 2289 HOH A O    1 
HETATM 6111 O  O    . HOH Q 6 .   ? -19.78768 1.58271   -4.64287  1.000 27.27171 ? 2290 HOH A O    1 
HETATM 6112 O  O    . HOH Q 6 .   ? -3.76348  -38.76453 -26.69734 1.000 34.33308 ? 2291 HOH A O    1 
HETATM 6113 O  O    . HOH Q 6 .   ? -7.50538  -42.53329 -9.81442  1.000 36.53598 ? 2292 HOH A O    1 
HETATM 6114 O  O    . HOH Q 6 .   ? -28.51145 -32.61411 0.36187   1.000 26.48477 ? 2293 HOH A O    1 
HETATM 6115 O  O    . HOH Q 6 .   ? 1.60872   -36.44730 -9.39836  1.000 32.50918 ? 2294 HOH A O    1 
HETATM 6116 O  O    . HOH Q 6 .   ? -14.84780 -3.30374  -26.58625 1.000 32.25652 ? 2295 HOH A O    1 
HETATM 6117 O  O    . HOH Q 6 .   ? -22.80668 3.38530   -8.98892  1.000 37.10184 ? 2296 HOH A O    1 
HETATM 6118 O  O    . HOH Q 6 .   ? 3.20821   2.41951   -11.18696 1.000 29.69305 ? 2297 HOH A O    1 
HETATM 6119 O  O    . HOH Q 6 .   ? -35.65750 -15.75238 -23.61172 1.000 29.96940 ? 2298 HOH A O    1 
HETATM 6120 O  O    . HOH Q 6 .   ? -26.38082 -36.23426 -30.43207 1.000 41.52079 ? 2299 HOH A O    1 
HETATM 6121 O  O    . HOH Q 6 .   ? -38.78218 -17.75590 -25.32476 1.000 24.85037 ? 2300 HOH A O    1 
HETATM 6122 O  O    . HOH Q 6 .   ? -2.96431  -13.97657 -18.89664 1.000 27.87968 ? 2301 HOH A O    1 
HETATM 6123 O  O    . HOH Q 6 .   ? -7.06776  -32.81681 1.58503   1.000 36.98077 ? 2302 HOH A O    1 
HETATM 6124 O  O    . HOH Q 6 .   ? -30.20641 -8.12985  -11.01328 1.000 22.12373 ? 2303 HOH A O    1 
HETATM 6125 O  O    . HOH Q 6 .   ? -27.57451 -25.23866 -1.69872  1.000 17.50738 ? 2304 HOH A O    1 
HETATM 6126 O  O    . HOH Q 6 .   ? -36.59039 -26.72832 -25.70541 1.000 31.53012 ? 2305 HOH A O    1 
HETATM 6127 O  O    . HOH Q 6 .   ? -21.85739 -11.03383 -28.44236 1.000 32.08808 ? 2306 HOH A O    1 
HETATM 6128 O  O    . HOH Q 6 .   ? 1.87762   -7.95572  -0.49650  1.000 32.97503 ? 2307 HOH A O    1 
HETATM 6129 O  O    . HOH Q 6 .   ? -43.58877 -9.84716  -5.06224  1.000 37.84140 ? 2308 HOH A O    1 
HETATM 6130 O  O    . HOH Q 6 .   ? 1.02768   -17.96282 -24.22696 1.000 28.97718 ? 2309 HOH A O    1 
HETATM 6131 O  O    . HOH Q 6 .   ? -19.95296 2.07877   -17.63054 1.000 34.24886 ? 2310 HOH A O    1 
HETATM 6132 O  O    . HOH Q 6 .   ? -27.51750 -5.30598  -7.42970  1.000 29.33775 ? 2311 HOH A O    1 
HETATM 6133 O  O    . HOH Q 6 .   ? 1.02050   -14.05341 1.35103   1.000 33.93567 ? 2312 HOH A O    1 
HETATM 6134 O  O    . HOH Q 6 .   ? -38.46670 -25.05921 -16.59231 1.000 34.30150 ? 2313 HOH A O    1 
HETATM 6135 O  O    . HOH Q 6 .   ? -4.36409  -39.20053 -3.98569  1.000 33.79091 ? 2314 HOH A O    1 
HETATM 6136 O  O    . HOH Q 6 .   ? -2.58337  -30.85024 -19.67863 1.000 19.72870 ? 2315 HOH A O    1 
HETATM 6137 O  O    . HOH Q 6 .   ? -40.70405 -12.06601 -13.54198 1.000 31.36694 ? 2316 HOH A O    1 
HETATM 6138 O  O    . HOH Q 6 .   ? -36.19113 -7.09490  -26.23414 1.000 33.38034 ? 2317 HOH A O    1 
HETATM 6139 O  O    . HOH Q 6 .   ? -12.60536 -20.48518 -35.30885 1.000 34.92789 ? 2318 HOH A O    1 
HETATM 6140 O  O    . HOH Q 6 .   ? -3.20956  -25.22607 -23.30180 1.000 22.59220 ? 2319 HOH A O    1 
HETATM 6141 O  O    . HOH Q 6 .   ? 0.89277   -15.50789 -26.53068 1.000 33.76723 ? 2320 HOH A O    1 
HETATM 6142 O  O    . HOH Q 6 .   ? -17.35973 -44.27775 -7.20741  1.000 33.26717 ? 2321 HOH A O    1 
HETATM 6143 O  O    . HOH Q 6 .   ? -28.21811 -37.84696 -22.09442 1.000 35.15950 ? 2322 HOH A O    1 
HETATM 6144 O  O    . HOH Q 6 .   ? -17.53212 -42.31468 -3.13404  1.000 31.54064 ? 2323 HOH A O    1 
HETATM 6145 O  O    . HOH Q 6 .   ? -1.87990  -12.01392 -6.84419  1.000 15.75454 ? 2324 HOH A O    1 
HETATM 6146 O  O    . HOH Q 6 .   ? 4.39335   0.52414   -9.30011  1.000 33.90935 ? 2325 HOH A O    1 
HETATM 6147 O  O    . HOH Q 6 .   ? -32.65593 -31.37557 -23.45077 1.000 33.36191 ? 2326 HOH A O    1 
HETATM 6148 O  O    . HOH Q 6 .   ? -3.13903  -29.57711 -28.66123 1.000 38.90732 ? 2327 HOH A O    1 
HETATM 6149 O  O    . HOH Q 6 .   ? -13.41492 -39.80663 -4.77712  1.000 21.02623 ? 2328 HOH A O    1 
HETATM 6150 O  O    . HOH Q 6 .   ? -19.89374 4.54652   -4.97618  1.000 34.90684 ? 2329 HOH A O    1 
HETATM 6151 O  O    . HOH Q 6 .   ? -10.97764 -30.96642 12.09361  1.000 35.13581 ? 2330 HOH A O    1 
HETATM 6152 O  O    . HOH Q 6 .   ? -0.39989  -17.03550 -28.43730 1.000 27.17170 ? 2331 HOH A O    1 
HETATM 6153 O  O    . HOH Q 6 .   ? -7.78453  -11.50344 -30.57005 1.000 29.94045 ? 2332 HOH A O    1 
HETATM 6154 O  O    . HOH Q 6 .   ? -29.61655 -20.89173 -2.80691  1.000 35.85958 ? 2333 HOH A O    1 
HETATM 6155 O  O    . HOH Q 6 .   ? -11.48300 -18.28438 -36.72627 1.000 31.12480 ? 2334 HOH A O    1 
HETATM 6156 O  O    . HOH Q 6 .   ? -31.87976 -11.12079 -3.83432  1.000 31.18797 ? 2335 HOH A O    1 
HETATM 6157 O  O    . HOH Q 6 .   ? -5.53840  -9.28546  -24.21782 1.000 26.15316 ? 2336 HOH A O    1 
HETATM 6158 O  O    . HOH Q 6 .   ? -13.69700 -41.66342 -2.80288  1.000 37.38871 ? 2337 HOH A O    1 
HETATM 6159 O  O    . HOH Q 6 .   ? -21.61998 -2.10548  -0.71759  1.000 36.27805 ? 2338 HOH A O    1 
HETATM 6160 O  O    . HOH Q 6 .   ? -16.51595 -44.17739 -11.04707 1.000 26.33476 ? 2339 HOH A O    1 
HETATM 6161 O  O    . HOH Q 6 .   ? -24.03406 -32.45397 -28.63127 1.000 36.74127 ? 2340 HOH A O    1 
HETATM 6162 O  O    . HOH Q 6 .   ? -24.51061 -5.22985  -1.04940  1.000 33.67511 ? 2341 HOH A O    1 
HETATM 6163 O  O    . HOH Q 6 .   ? -2.17091  -6.77908  -16.70057 1.000 35.01211 ? 2342 HOH A O    1 
HETATM 6164 O  O    . HOH Q 6 .   ? -7.63834  -13.47909 -32.52029 1.000 28.36658 ? 2343 HOH A O    1 
HETATM 6165 O  O    . HOH Q 6 .   ? -22.31760 -35.58148 -36.30125 1.000 35.00422 ? 2344 HOH A O    1 
HETATM 6166 O  O    . HOH Q 6 .   ? -2.37703  -25.07881 5.59845   1.000 34.56206 ? 2345 HOH A O    1 
HETATM 6167 O  O    . HOH Q 6 .   ? -23.43360 -28.45621 -26.09602 1.000 30.40103 ? 2346 HOH A O    1 
HETATM 6168 O  O    . HOH Q 6 .   ? -2.84712  -21.13220 -28.89092 1.000 19.86819 ? 2347 HOH A O    1 
HETATM 6169 O  O    . HOH Q 6 .   ? -14.65313 -44.31032 -9.48183  1.000 31.42747 ? 2348 HOH A O    1 
HETATM 6170 O  O    . HOH Q 6 .   ? -0.42845  -19.77987 -28.32438 1.000 19.91820 ? 2349 HOH A O    1 
HETATM 6171 O  O    . HOH Q 6 .   ? -39.75097 -26.39088 -10.20777 1.000 30.70107 ? 2350 HOH A O    1 
HETATM 6172 O  O    . HOH Q 6 .   ? -4.61579  2.00683   -14.97952 1.000 19.55236 ? 2351 HOH A O    1 
HETATM 6173 O  O    . HOH Q 6 .   ? -22.80352 -30.14729 9.01235   1.000 31.38536 ? 2352 HOH A O    1 
HETATM 6174 O  O    . HOH Q 6 .   ? -2.60154  0.52747   -16.47400 1.000 19.89451 ? 2353 HOH A O    1 
HETATM 6175 O  O    . HOH Q 6 .   ? -19.94715 -27.56788 -1.17951  1.000 22.13162 ? 2354 HOH A O    1 
HETATM 6176 O  O    . HOH Q 6 .   ? -37.29683 -20.83835 -19.65610 1.000 18.54435 ? 2355 HOH A O    1 
HETATM 6177 O  O    . HOH Q 6 .   ? -15.22447 -33.02974 11.45000  1.000 31.21955 ? 2356 HOH A O    1 
HETATM 6178 O  O    . HOH Q 6 .   ? -22.25971 -17.20015 -34.67347 1.000 34.85157 ? 2357 HOH A O    1 
HETATM 6179 O  O    . HOH Q 6 .   ? -9.40612  -16.21985 -35.72905 1.000 40.12325 ? 2358 HOH A O    1 
HETATM 6180 O  O    . HOH Q 6 .   ? -38.81612 -9.44209  -9.64218  1.000 41.58395 ? 2359 HOH A O    1 
HETATM 6181 O  O    . HOH Q 6 .   ? -19.09968 -5.04246  -26.46841 1.000 32.80658 ? 2360 HOH A O    1 
HETATM 6182 O  O    . HOH Q 6 .   ? -40.62749 -10.55217 -11.07915 1.000 31.51696 ? 2361 HOH A O    1 
HETATM 6183 O  O    . HOH Q 6 .   ? -34.49097 -31.14035 -14.74581 1.000 33.64879 ? 2362 HOH A O    1 
HETATM 6184 O  O    . HOH Q 6 .   ? 0.00004   -3.35613  -15.46098 0.511 20.34983 ? 2363 HOH A O    1 
HETATM 6185 O  O    . HOH Q 6 .   ? -34.28906 -28.08907 -25.78986 1.000 42.60513 ? 2364 HOH A O    1 
HETATM 6186 O  O    . HOH Q 6 .   ? -0.27675  -13.28090 -25.26560 1.000 24.23714 ? 2365 HOH A O    1 
HETATM 6187 O  O    . HOH Q 6 .   ? -37.28315 -27.70100 -13.20495 1.000 43.27626 ? 2366 HOH A O    1 
HETATM 6188 O  O    . HOH Q 6 .   ? -3.56206  -12.97303 -30.52565 1.000 31.49853 ? 2367 HOH A O    1 
HETATM 6189 O  O    . HOH Q 6 .   ? -16.41783 -7.17566  14.14769  1.000 34.63838 ? 2368 HOH A O    1 
HETATM 6190 O  O    . HOH Q 6 .   ? -24.77598 1.31395   -10.60697 1.000 39.94691 ? 2369 HOH A O    1 
HETATM 6191 O  O    . HOH Q 6 .   ? -35.22578 -2.94845  -19.58140 1.000 36.44123 ? 2370 HOH A O    1 
HETATM 6192 O  O    . HOH Q 6 .   ? -2.25712  -16.64064 -30.25463 1.000 25.78732 ? 2371 HOH A O    1 
HETATM 6193 O  O    . HOH Q 6 .   ? -16.64384 -4.72784  -27.39025 1.000 37.34923 ? 2372 HOH A O    1 
HETATM 6194 O  O    . HOH Q 6 .   ? -17.60090 -22.13536 13.15392  1.000 34.37783 ? 2373 HOH A O    1 
HETATM 6195 O  O    . HOH Q 6 .   ? -30.76846 -5.69661  -13.19808 1.000 33.73038 ? 2374 HOH A O    1 
HETATM 6196 O  O    . HOH Q 6 .   ? -1.17588  -11.28911 -16.01278 1.000 30.48525 ? 2375 HOH A O    1 
HETATM 6197 O  O    . HOH Q 6 .   ? -1.29779  -8.69826  9.04965   1.000 35.49901 ? 2376 HOH A O    1 
HETATM 6198 O  O    . HOH Q 6 .   ? -19.25133 -20.25402 11.48640  1.000 27.58754 ? 2377 HOH A O    1 
HETATM 6199 O  O    . HOH Q 6 .   ? -26.14842 -31.18815 -26.59903 1.000 31.60381 ? 2378 HOH A O    1 
HETATM 6200 O  O    . HOH Q 6 .   ? 0.18365   -5.59244  -15.12385 0.616 31.76699 ? 2379 HOH A O    1 
HETATM 6201 O  O    . HOH Q 6 .   ? -27.09946 -23.69600 -18.77861 1.000 14.57808 ? 2380 HOH A O    1 
HETATM 6202 O  O    . HOH Q 6 .   ? 0.44452   3.48472   -11.90715 1.000 24.17397 ? 2381 HOH A O    1 
HETATM 6203 O  O    . HOH Q 6 .   ? -29.90990 -23.92351 -1.89395  1.000 29.21931 ? 2382 HOH A O    1 
HETATM 6204 O  O    . HOH Q 6 .   ? -4.83621  3.36299   -17.71465 1.000 34.32519 ? 2383 HOH A O    1 
HETATM 6205 O  O    . HOH Q 6 .   ? -28.43797 -24.25536 6.55771   1.000 34.38572 ? 2384 HOH A O    1 
HETATM 6206 O  O    . HOH Q 6 .   ? -16.54195 -27.31190 14.48882  1.000 39.43633 ? 2385 HOH A O    1 
HETATM 6207 O  O    . HOH Q 6 .   ? 0.43519   6.56037   -8.20396  1.000 28.16919 ? 2386 HOH A O    1 
HETATM 6208 O  O    . HOH Q 6 .   ? -26.62581 -38.75875 -17.75292 1.000 44.34481 ? 2387 HOH A O    1 
HETATM 6209 O  O    . HOH Q 6 .   ? -21.64079 -28.59028 -38.30062 1.000 33.93567 ? 2388 HOH A O    1 
HETATM 6210 O  O    . HOH Q 6 .   ? -26.23428 -20.05230 4.99959   1.000 30.06941 ? 2389 HOH A O    1 
HETATM 6211 O  O    . HOH Q 6 .   ? -7.00432  -39.29235 -3.85554  1.000 27.24013 ? 2390 HOH A O    1 
HETATM 6212 O  O    . HOH Q 6 .   ? -0.00001  -34.86422 -15.45997 0.680 33.51720 ? 2391 HOH A O    1 
HETATM 6213 O  O    . HOH Q 6 .   ? -37.18417 -19.24622 -4.31916  1.000 44.89751 ? 2392 HOH A O    1 
HETATM 6214 O  O    . HOH Q 6 .   ? -6.37281  -17.28694 15.80882  1.000 31.25903 ? 2393 HOH A O    1 
HETATM 6215 O  O    . HOH Q 6 .   ? -39.26277 -6.09844  -17.69508 1.000 28.15866 ? 2394 HOH A O    1 
HETATM 6216 O  O    . HOH Q 6 .   ? -12.73386 -32.67070 10.08009  1.000 41.58658 ? 2395 HOH A O    1 
HETATM 6217 O  O    . HOH Q 6 .   ? -9.75238  -13.54602 14.83616  1.000 31.49590 ? 2396 HOH A O    1 
HETATM 6218 O  O    . HOH Q 6 .   ? -0.48307  -11.37761 -9.02822  1.000 22.62115 ? 2397 HOH A O    1 
HETATM 6219 O  O    . HOH Q 6 .   ? -0.87295  -9.53079  -14.70750 1.000 29.32985 ? 2398 HOH A O    1 
HETATM 6220 O  O    . HOH Q 6 .   ? -34.59539 -18.79036 -30.59067 1.000 30.80898 ? 2399 HOH A O    1 
HETATM 6221 O  O    . HOH Q 6 .   ? -38.10509 -21.31517 -29.46093 1.000 33.73301 ? 2400 HOH A O    1 
HETATM 6222 O  O    . HOH Q 6 .   ? -1.13804  -6.27845  -19.12913 1.000 29.80623 ? 2401 HOH A O    1 
HETATM 6223 O  O    . HOH Q 6 .   ? 0.25974   -34.72547 -13.13744 1.000 22.84223 ? 2402 HOH A O    1 
HETATM 6224 O  O    . HOH Q 6 .   ? -2.23505  -15.54270 -7.79710  1.000 26.55584 ? 2403 HOH A O    1 
HETATM 6225 O  O    . HOH Q 6 .   ? -12.73451 -5.94598  17.26261  1.000 28.47449 ? 2404 HOH A O    1 
HETATM 6226 O  O    . HOH Q 6 .   ? -23.18332 -5.65173  -25.52688 1.000 43.79474 ? 2405 HOH A O    1 
HETATM 6227 O  O    . HOH Q 6 .   ? -4.87234  -5.02922  -24.58808 1.000 30.10363 ? 2406 HOH A O    1 
HETATM 6228 O  O    . HOH Q 6 .   ? -35.42531 -5.60884  -14.97463 1.000 29.53777 ? 2407 HOH A O    1 
HETATM 6229 O  O    . HOH Q 6 .   ? -25.42595 -38.45447 -5.80353  1.000 33.49088 ? 2408 HOH A O    1 
HETATM 6230 O  O    . HOH Q 6 .   ? -20.08116 -46.46607 -10.32686 1.000 39.62319 ? 2409 HOH A O    1 
HETATM 6231 O  O    . HOH Q 6 .   ? -32.71919 -4.41888  -11.58792 1.000 45.00542 ? 2410 HOH A O    1 
HETATM 6232 O  O    . HOH Q 6 .   ? -0.50512  -33.83825 0.49365   1.000 45.27650 ? 2411 HOH A O    1 
HETATM 6233 O  O    . HOH Q 6 .   ? -33.56064 -5.94543  -13.27697 1.000 36.62020 ? 2412 HOH A O    1 
HETATM 6234 O  O    . HOH Q 6 .   ? -10.12684 -5.74971  16.48086  1.000 26.17947 ? 2413 HOH A O    1 
HETATM 6235 O  O    . HOH Q 6 .   ? -1.15549  -12.82819 -27.93279 1.000 33.33560 ? 2414 HOH A O    1 
HETATM 6236 O  O    . HOH Q 6 .   ? -24.28291 -23.37376 9.81624   1.000 32.23810 ? 2415 HOH A O    1 
HETATM 6237 O  O    . HOH Q 6 .   ? -8.45270  4.41088   -14.97493 1.000 27.62175 ? 2416 HOH A O    1 
HETATM 6238 O  O    . HOH Q 6 .   ? -31.08512 -34.45772 -13.12107 1.000 34.02252 ? 2417 HOH A O    1 
HETATM 6239 O  O    . HOH Q 6 .   ? -30.20023 -29.24532 -26.61282 1.000 28.37184 ? 2418 HOH A O    1 
HETATM 6240 O  O    . HOH Q 6 .   ? -18.71645 -3.40240  15.09685  1.000 22.96856 ? 2419 HOH A O    1 
HETATM 6241 O  O    . HOH Q 6 .   ? -28.41584 -27.80689 -27.16145 1.000 37.86509 ? 2420 HOH A O    1 
HETATM 6242 O  O    . HOH Q 6 .   ? -5.93583  -27.45920 -34.66649 1.000 39.83374 ? 2421 HOH A O    1 
HETATM 6243 O  O    . HOH Q 6 .   ? -4.56198  -27.74311 -32.37513 1.000 35.01211 ? 2422 HOH A O    1 
HETATM 6244 O  O    . HOH Q 6 .   ? -1.70579  -9.84638  -22.09164 1.000 22.99225 ? 2423 HOH A O    1 
HETATM 6245 O  O    . HOH Q 6 .   ? -12.30658 -44.41698 -10.94795 1.000 33.72512 ? 2424 HOH A O    1 
HETATM 6246 O  O    . HOH Q 6 .   ? -27.34847 -39.07250 -9.31840  1.000 34.96211 ? 2425 HOH A O    1 
HETATM 6247 O  O    . HOH Q 6 .   ? -14.93830 -5.63045  15.79406  1.000 34.06989 ? 2426 HOH A O    1 
HETATM 6248 O  O    . HOH Q 6 .   ? -3.66356  3.92903   -13.29762 1.000 22.31322 ? 2427 HOH A O    1 
HETATM 6249 O  O    . HOH Q 6 .   ? -4.91074  -13.84832 -32.75938 1.000 36.03592 ? 2428 HOH A O    1 
HETATM 6250 O  O    . HOH Q 6 .   ? -23.91317 -33.95051 8.41387   1.000 26.66111 ? 2429 HOH A O    1 
HETATM 6251 O  O    . HOH Q 6 .   ? -3.15945  -31.48321 -30.70775 1.000 34.66733 ? 2430 HOH A O    1 
HETATM 6252 O  O    . HOH Q 6 .   ? -16.33494 -45.69980 -13.89938 1.000 31.19850 ? 2431 HOH A O    1 
HETATM 6253 O  O    . HOH Q 6 .   ? -41.04899 -5.37575  -15.46104 0.559 35.15950 ? 2432 HOH A O    1 
HETATM 6254 O  O    . HOH Q 6 .   ? 3.60492   -34.76416 -10.11635 1.000 21.49207 ? 2433 HOH A O    1 
HETATM 6255 O  O    . HOH Q 6 .   ? -42.00195 -8.04819  -11.34651 1.000 24.83984 ? 2434 HOH A O    1 
HETATM 6256 O  O    . HOH Q 6 .   ? -2.66347  -16.91220 -33.16116 1.000 32.19862 ? 2435 HOH A O    1 
HETATM 6257 O  O    . HOH Q 6 .   ? -40.26873 -6.30363  -10.33933 1.000 33.83302 ? 2436 HOH A O    1 
HETATM 6258 O  O    . HOH Q 6 .   ? -1.13546  2.82735   -16.19076 1.000 26.07420 ? 2437 HOH A O    1 
HETATM 6259 O  O    . HOH Q 6 .   ? -1.82789  -28.05425 -32.34993 1.000 32.45391 ? 2438 HOH A O    1 
HETATM 6260 O  O    . HOH Q 6 .   ? -14.26921 -42.25291 -27.87036 1.000 29.93782 ? 2439 HOH A O    1 
HETATM 6261 O  O    . HOH Q 6 .   ? -2.43019  5.11229   -15.25539 1.000 39.96797 ? 2440 HOH A O    1 
HETATM 6262 O  O    . HOH Q 6 .   ? 173.37199 6.89582   89.79867  1.000 34.09095 ? 2441 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N  N   . LYS A 1   ? 0.45540 0.39850 0.40590 -0.01020 0.02450  -0.03260 1460 LYS A N   
2    C  CA  . LYS A 1   ? 0.44500 0.39390 0.40740 -0.01180 0.02320  -0.02930 1460 LYS A CA  
3    C  C   . LYS A 1   ? 0.41560 0.38320 0.39820 -0.01050 0.01250  -0.02570 1460 LYS A C   
4    O  O   . LYS A 1   ? 0.43470 0.38710 0.40310 -0.00460 0.01810  -0.02200 1460 LYS A O   
5    C  CB  . LYS A 1   ? 0.45620 0.39740 0.41630 -0.01400 0.02500  -0.02850 1460 LYS A CB  
7    N  N   . LEU A 2   ? 0.35340 0.36690 0.37100 -0.01560 0.00010  -0.03090 1461 LEU A N   
8    C  CA  . LEU A 2   ? 0.30680 0.34820 0.33940 -0.01950 0.01070  -0.04780 1461 LEU A CA  
9    C  C   . LEU A 2   ? 0.27100 0.32950 0.30790 -0.01850 0.02000  -0.06530 1461 LEU A C   
10   O  O   . LEU A 2   ? 0.28610 0.33480 0.33320 -0.00890 0.04390  -0.08860 1461 LEU A O   
11   C  CB  . LEU A 2   ? 0.31100 0.34680 0.34920 -0.01920 0.01150  -0.04740 1461 LEU A CB  
12   C  CG  . LEU A 2   ? 0.31720 0.34650 0.36230 -0.02280 0.00800  -0.04490 1461 LEU A CG  
13   C  CD1 . LEU A 2   ? 0.33780 0.34730 0.37860 -0.02570 -0.00540 -0.04170 1461 LEU A CD1 
14   C  CD2 . LEU A 2   ? 0.30460 0.34610 0.36750 -0.02410 0.01340  -0.04400 1461 LEU A CD2 
26   N  N   . VAL A 3   ? 0.22790 0.30370 0.24950 -0.02670 0.01450  -0.05030 1462 VAL A N   
27   C  CA  . VAL A 3   ? 0.21610 0.28100 0.22060 -0.02820 0.01760  -0.02850 1462 VAL A CA  
28   C  C   . VAL A 3   ? 0.19310 0.25310 0.19900 -0.02540 0.04180  -0.02590 1462 VAL A C   
29   O  O   . VAL A 3   ? 0.18760 0.24530 0.19470 -0.02500 0.05170  -0.01300 1462 VAL A O   
30   C  CB  . VAL A 3   ? 0.25520 0.28430 0.24010 -0.04000 -0.01350 -0.00880 1462 VAL A CB  
31   C  CG1 . VAL A 3   ? 0.27690 0.28530 0.25920 -0.04490 -0.02580 -0.00210 1462 VAL A CG1 
32   C  CG2 . VAL A 3   ? 0.27280 0.28690 0.24870 -0.04230 -0.01820 -0.00460 1462 VAL A CG2 
42   N  N   . ARG A 4   ? 0.18250 0.23920 0.19030 -0.01720 0.05690  -0.03750 1463 ARG A N   
43   C  CA  . ARG A 4   ? 0.18560 0.22700 0.20120 -0.01350 0.04290  -0.04030 1463 ARG A CA  
44   C  C   . ARG A 4   ? 0.18690 0.20640 0.19220 -0.03920 0.04710  -0.03920 1463 ARG A C   
45   O  O   . ARG A 4   ? 0.22200 0.22520 0.23000 -0.05650 0.06680  -0.03760 1463 ARG A O   
46   C  CB  . ARG A 4   ? 0.20610 0.23850 0.22840 -0.00040 0.03650  -0.04030 1463 ARG A CB  
47   C  CG  . ARG A 4   ? 0.23550 0.25270 0.24830 0.01370  0.02510  -0.02870 1463 ARG A CG  
48   C  CD  . ARG A 4   ? 0.25960 0.26280 0.26020 0.01530  0.02120  -0.01670 1463 ARG A CD  
49   N  NE  . ARG A 4   ? 0.25980 0.26800 0.26330 0.01450  0.03190  -0.00380 1463 ARG A NE  
50   C  CZ  . ARG A 4   ? 0.27120 0.27400 0.28590 0.00790  0.04420  -0.00660 1463 ARG A CZ  
51   N  NH1 . ARG A 4   ? 0.30040 0.27860 0.31940 0.00390  0.04050  -0.00470 1463 ARG A NH1 
52   N  NH2 . ARG A 4   ? 0.25250 0.27380 0.27890 0.00810  0.05100  -0.00350 1463 ARG A NH2 
66   N  N   . LEU A 5   ? 0.17590 0.17660 0.16840 -0.03470 0.04750  -0.02650 1464 LEU A N   
67   C  CA  . LEU A 5   ? 0.16950 0.15730 0.16400 -0.02970 0.04550  -0.02010 1464 LEU A CA  
68   C  C   . LEU A 5   ? 0.16330 0.14650 0.15740 -0.02230 0.03530  -0.01330 1464 LEU A C   
69   O  O   . LEU A 5   ? 0.16150 0.13560 0.16980 -0.01730 0.02910  -0.01520 1464 LEU A O   
70   C  CB  . LEU A 5   ? 0.18450 0.15260 0.16450 -0.02500 0.02570  -0.02010 1464 LEU A CB  
71   C  CG  . LEU A 5   ? 0.21000 0.15260 0.19020 -0.02330 -0.00740 -0.01760 1464 LEU A CG  
72   C  CD1 . LEU A 5   ? 0.22570 0.15350 0.20280 -0.01230 -0.01310 -0.02500 1464 LEU A CD1 
73   C  CD2 . LEU A 5   ? 0.22900 0.15020 0.19600 -0.02380 -0.02250 -0.00450 1464 LEU A CD2 
85   N  N   . PRO A 6   ? 0.17690 0.14470 0.16700 -0.03250 0.03050  -0.01450 1465 PRO A N   
86   C  CA  . PRO A 6   ? 0.17440 0.14940 0.16990 -0.02570 0.03490  -0.02380 1465 PRO A CA  
87   C  C   . PRO A 6   ? 0.17330 0.14440 0.16280 -0.00970 0.04630  -0.02530 1465 PRO A C   
88   O  O   . PRO A 6   ? 0.18810 0.14990 0.17770 -0.01020 0.01550  -0.03110 1465 PRO A O   
89   C  CB  . PRO A 6   ? 0.18860 0.15430 0.19340 -0.02760 0.03320  -0.03120 1465 PRO A CB  
90   C  CG  . PRO A 6   ? 0.19280 0.15460 0.20730 -0.03500 0.02550  -0.02250 1465 PRO A CG  
91   C  CD  . PRO A 6   ? 0.19290 0.14670 0.19310 -0.02990 0.01570  -0.02610 1465 PRO A CD  
99   N  N   . GLY A 7   ? 0.16950 0.13370 0.18050 0.00130  0.06400  -0.02450 1466 GLY A N   
100  C  CA  . GLY A 7   ? 0.16630 0.12600 0.17820 -0.00050 0.06460  -0.02230 1466 GLY A CA  
101  C  C   . GLY A 7   ? 0.14140 0.12150 0.18400 -0.00540 0.03460  -0.02710 1466 GLY A C   
102  O  O   . GLY A 7   ? 0.12880 0.12450 0.21350 -0.00760 0.00400  -0.01120 1466 GLY A O   
106  N  N   . LEU A 8   ? 0.12940 0.11910 0.17690 -0.01430 0.03110  -0.03650 1467 LEU A N   
107  C  CA  . LEU A 8   ? 0.11480 0.11750 0.15590 -0.01750 0.01160  -0.02590 1467 LEU A CA  
108  C  C   . LEU A 8   ? 0.11170 0.10850 0.15260 -0.01040 0.00460  -0.02010 1467 LEU A C   
109  O  O   . LEU A 8   ? 0.11890 0.11170 0.16640 -0.01760 -0.00050 -0.01520 1467 LEU A O   
110  C  CB  . LEU A 8   ? 0.11430 0.13250 0.16090 -0.02600 0.02070  -0.01920 1467 LEU A CB  
111  C  CG  . LEU A 8   ? 0.12800 0.14700 0.17420 -0.02140 0.01190  -0.02680 1467 LEU A CG  
112  C  CD1 . LEU A 8   ? 0.14590 0.15940 0.19930 -0.02150 -0.00600 -0.02000 1467 LEU A CD1 
113  C  CD2 . LEU A 8   ? 0.12510 0.14850 0.17130 -0.02880 0.02400  -0.02650 1467 LEU A CD2 
125  N  N   . ILE A 9   ? 0.12720 0.10400 0.12860 -0.01010 0.01300  -0.02020 1468 ILE A N   
126  C  CA  . ILE A 9   ? 0.11540 0.10700 0.12960 -0.00360 0.01690  -0.01180 1468 ILE A CA  
127  C  C   . ILE A 9   ? 0.11390 0.10700 0.13260 -0.00310 0.00870  -0.01400 1468 ILE A C   
128  O  O   . ILE A 9   ? 0.12360 0.11190 0.16880 -0.00270 0.02610  -0.00160 1468 ILE A O   
129  C  CB  . ILE A 9   ? 0.11610 0.11210 0.14500 -0.00550 0.00370  -0.00160 1468 ILE A CB  
130  C  CG1 . ILE A 9   ? 0.10810 0.12030 0.18050 0.00270  0.00680  0.01640  1468 ILE A CG1 
131  C  CG2 . ILE A 9   ? 0.12440 0.11680 0.15850 -0.00910 0.00110  -0.00170 1468 ILE A CG2 
132  C  CD1 . ILE A 9   ? 0.11510 0.12470 0.20670 0.00390  0.01400  0.02480  1468 ILE A CD1 
144  N  N   . ASP A 10  ? 0.11450 0.10810 0.13970 -0.01190 0.00690  -0.02550 1469 ASP A N   
145  C  CA  . ASP A 10  ? 0.10310 0.11270 0.13170 -0.00140 0.00410  -0.01140 1469 ASP A CA  
146  C  C   . ASP A 10  ? 0.11680 0.10800 0.12330 0.00480  0.00160  -0.00290 1469 ASP A C   
147  O  O   . ASP A 10  ? 0.13290 0.10970 0.13560 0.00810  0.01400  0.01470  1469 ASP A O   
148  C  CB  . ASP A 10  ? 0.10430 0.12140 0.13120 0.00320  0.01190  -0.00290 1469 ASP A CB  
149  C  CG  . ASP A 10  ? 0.12570 0.12830 0.13110 0.00320  -0.00200 -0.00680 1469 ASP A CG  
150  O  OD1 . ASP A 10  ? 0.12660 0.12720 0.14480 -0.00210 0.00350  -0.02070 1469 ASP A OD1 
151  O  OD2 . ASP A 10  ? 0.14940 0.14060 0.14810 0.02630  -0.01620 -0.01640 1469 ASP A OD2 
156  N  N   . VAL A 11  ? 0.10890 0.10690 0.13130 0.00180  -0.00550 -0.01720 1470 VAL A N   
157  C  CA  . VAL A 11  ? 0.11470 0.11520 0.12230 0.00120  -0.00260 -0.01470 1470 VAL A CA  
158  C  C   . VAL A 11  ? 0.11470 0.10520 0.11020 -0.00270 -0.00730 -0.00210 1470 VAL A C   
159  O  O   . VAL A 11  ? 0.12070 0.11540 0.13690 0.00620  -0.01070 0.00350  1470 VAL A O   
160  C  CB  . VAL A 11  ? 0.10950 0.12260 0.12530 -0.00510 0.00440  -0.01770 1470 VAL A CB  
161  C  CG1 . VAL A 11  ? 0.11150 0.12590 0.14530 -0.01880 0.01340  -0.01720 1470 VAL A CG1 
162  C  CG2 . VAL A 11  ? 0.12920 0.13040 0.13620 -0.01090 0.00130  -0.01590 1470 VAL A CG2 
172  N  N   . HIS A 12  ? 0.11520 0.10620 0.12370 -0.00330 -0.00190 -0.00130 1471 HIS A N   
173  C  CA  . HIS A 12  ? 0.11810 0.11680 0.11760 -0.00030 -0.00850 0.00080  1471 HIS A CA  
174  C  C   . HIS A 12  ? 0.11270 0.11810 0.11300 0.00160  -0.00430 0.01060  1471 HIS A C   
175  O  O   . HIS A 12  ? 0.10960 0.11990 0.12860 -0.00340 -0.00310 0.00040  1471 HIS A O   
176  C  CB  . HIS A 12  ? 0.10200 0.11850 0.11250 -0.00510 0.01650  -0.00770 1471 HIS A CB  
177  C  CG  . HIS A 12  ? 0.10420 0.11820 0.11640 0.00230  0.01470  -0.01480 1471 HIS A CG  
178  N  ND1 . HIS A 12  ? 0.12180 0.12440 0.15210 0.00250  0.01620  -0.02350 1471 HIS A ND1 
179  C  CD2 . HIS A 12  ? 0.09580 0.11380 0.09650 -0.00930 0.01190  -0.01500 1471 HIS A CD2 
180  C  CE1 . HIS A 12  ? 0.11630 0.12330 0.13230 0.00230  0.01230  -0.02600 1471 HIS A CE1 
181  N  NE2 . HIS A 12  ? 0.11190 0.12100 0.10900 -0.01030 0.00610  -0.00550 1471 HIS A NE2 
188  N  N   . VAL A 13  ? 0.10700 0.11830 0.12610 -0.00550 0.00090  0.00510  1472 VAL A N   
189  C  CA  . VAL A 13  ? 0.11550 0.12500 0.13190 -0.00380 -0.00380 -0.01820 1472 VAL A CA  
190  C  C   . VAL A 13  ? 0.10790 0.12480 0.13550 -0.01080 -0.00080 -0.00800 1472 VAL A C   
191  O  O   . VAL A 13  ? 0.11070 0.14020 0.13980 -0.00710 0.00740  -0.00520 1472 VAL A O   
192  C  CB  . VAL A 13  ? 0.14180 0.12750 0.11620 -0.00420 0.00190  -0.01800 1472 VAL A CB  
193  C  CG1 . VAL A 13  ? 0.17350 0.13450 0.12070 -0.01340 0.00280  -0.01770 1472 VAL A CG1 
194  C  CG2 . VAL A 13  ? 0.14620 0.13280 0.15240 0.01110  0.00240  -0.01320 1472 VAL A CG2 
204  N  N   . HIS A 14  ? 0.10430 0.11720 0.15350 -0.01520 0.00410  -0.00310 1473 HIS A N   
205  C  CA  . HIS A 14  ? 0.10470 0.12490 0.13950 -0.01400 0.00840  0.00310  1473 HIS A CA  
206  C  C   . HIS A 14  ? 0.10670 0.13500 0.16330 -0.00920 -0.02010 0.00550  1473 HIS A C   
207  O  O   . HIS A 14  ? 0.11900 0.14030 0.17410 -0.02030 -0.01830 0.01230  1473 HIS A O   
208  C  CB  . HIS A 14  ? 0.10380 0.12270 0.12280 -0.01030 0.00710  -0.00230 1473 HIS A CB  
209  C  CG  . HIS A 14  ? 0.11150 0.12200 0.13110 -0.00540 0.00600  0.00080  1473 HIS A CG  
210  N  ND1 . HIS A 14  ? 0.10560 0.12330 0.14990 -0.00330 0.00950  -0.00450 1473 HIS A ND1 
211  C  CD2 . HIS A 14  ? 0.10540 0.11710 0.12580 -0.00960 -0.01110 -0.00540 1473 HIS A CD2 
212  C  CE1 . HIS A 14  ? 0.11380 0.12280 0.14000 0.00160  0.00400  0.00150  1473 HIS A CE1 
213  N  NE2 . HIS A 14  ? 0.10510 0.12040 0.11960 -0.00080 0.01030  0.00010  1473 HIS A NE2 
221  N  N   . LEU A 15  ? 0.10350 0.13990 0.15900 -0.01220 -0.00910 0.00020  1474 LEU A N   
222  C  CA  . LEU A 15  ? 0.12560 0.14540 0.15380 -0.01330 0.00770  -0.00180 1474 LEU A CA  
223  C  C   . LEU A 15  ? 0.13360 0.14790 0.16290 -0.01500 0.00770  -0.00470 1474 LEU A C   
224  O  O   . LEU A 15  ? 0.14040 0.14230 0.18160 -0.02290 0.00730  -0.00830 1474 LEU A O   
225  C  CB  . LEU A 15  ? 0.14950 0.15320 0.15970 -0.00910 0.03840  -0.01390 1474 LEU A CB  
226  C  CG  . LEU A 15  ? 0.16900 0.16680 0.18340 -0.00660 0.02840  -0.01150 1474 LEU A CG  
227  C  CD1 . LEU A 15  ? 0.20180 0.16450 0.22060 -0.00550 0.04140  -0.00980 1474 LEU A CD1 
228  C  CD2 . LEU A 15  ? 0.19450 0.18150 0.20080 -0.00770 0.02910  -0.01940 1474 LEU A CD2 
240  N  N   . ARG A 16  ? 0.12830 0.15390 0.15110 -0.01310 0.00090  0.00430  1475 ARG A N   
241  C  CA  . ARG A 16  ? 0.13440 0.16420 0.15880 -0.00570 0.01260  0.02770  1475 ARG A CA  
242  C  C   . ARG A 16  ? 0.13910 0.17730 0.21000 -0.00420 0.03800  0.05400  1475 ARG A C   
243  O  O   . ARG A 16  ? 0.18100 0.20300 0.25450 0.01520  0.06020  0.06610  1475 ARG A O   
244  C  CB  . ARG A 16  ? 0.13650 0.16310 0.14470 -0.01070 0.01050  0.01830  1475 ARG A CB  
245  C  CG  . ARG A 16  ? 0.14650 0.15980 0.15720 -0.00260 0.00160  0.00730  1475 ARG A CG  
246  C  CD  . ARG A 16  ? 0.15800 0.15610 0.15520 -0.00260 -0.01180 0.00030  1475 ARG A CD  
247  N  NE  . ARG A 16  ? 0.14080 0.15590 0.15600 0.00080  -0.02240 0.00580  1475 ARG A NE  
248  C  CZ  . ARG A 16  ? 0.13560 0.15450 0.14400 -0.00260 -0.01550 0.01020  1475 ARG A CZ  
249  N  NH1 . ARG A 16  ? 0.15050 0.15260 0.16090 -0.00180 -0.01830 0.00590  1475 ARG A NH1 
250  N  NH2 . ARG A 16  ? 0.14680 0.16350 0.13690 -0.00910 -0.00730 0.00950  1475 ARG A NH2 
264  N  N   . GLU A 17  ? 0.14530 0.17170 0.21340 -0.00940 0.01860  0.05780  1476 GLU A N   
265  C  CA  . GLU A 17  ? 0.16370 0.16660 0.20030 -0.02100 0.00900  0.04720  1476 GLU A CA  
266  C  C   . GLU A 17  ? 0.17580 0.16990 0.22930 -0.02780 0.00200  0.04020  1476 GLU A C   
267  O  O   . GLU A 17  ? 0.18390 0.16530 0.26720 -0.03320 0.00040  0.02690  1476 GLU A O   
268  C  CB  . GLU A 17  ? 0.16420 0.16430 0.17760 -0.01720 -0.00060 0.02940  1476 GLU A CB  
269  C  CG  . GLU A 17  ? 0.17110 0.16290 0.18860 -0.01600 -0.00890 0.01910  1476 GLU A CG  
270  C  CD  . GLU A 17  ? 0.19430 0.16070 0.20020 -0.01530 -0.00290 0.01880  1476 GLU A CD  
271  O  OE1 . GLU A 17  ? 0.20160 0.15680 0.20810 -0.00940 0.00840  0.00950  1476 GLU A OE1 
272  O  OE2 . GLU A 17  ? 0.22450 0.16460 0.21770 -0.02220 0.01850  0.02220  1476 GLU A OE2 
279  N  N   . PRO A 18  ? 0.19900 0.18370 0.22130 -0.01820 -0.01530 0.03670  1477 PRO A N   
280  C  CA  . PRO A 18  ? 0.19710 0.19210 0.20760 -0.00990 -0.00650 0.03530  1477 PRO A CA  
281  C  C   . PRO A 18  ? 0.19480 0.20450 0.20580 -0.01940 -0.00030 0.02240  1477 PRO A C   
282  O  O   . PRO A 18  ? 0.19330 0.19520 0.20860 -0.02540 0.00010  0.02090  1477 PRO A O   
283  C  CB  . PRO A 18  ? 0.21480 0.19320 0.21880 -0.00830 -0.00370 0.04130  1477 PRO A CB  
284  C  CG  . PRO A 18  ? 0.22970 0.19140 0.23330 -0.01120 -0.01780 0.03480  1477 PRO A CG  
285  C  CD  . PRO A 18  ? 0.21750 0.18750 0.23720 -0.01070 -0.02220 0.03360  1477 PRO A CD  
293  N  N   . GLY A 19  ? 0.20030 0.22350 0.19020 -0.02390 -0.00030 0.01700  1478 GLY A N   
294  C  CA  . GLY A 19  ? 0.20150 0.23610 0.21710 -0.02710 0.01100  0.01610  1478 GLY A CA  
295  C  C   . GLY A 19  ? 0.19980 0.24480 0.23270 -0.02680 0.01020  0.01510  1478 GLY A C   
296  O  O   . GLY A 19  ? 0.21790 0.26010 0.25350 -0.01960 0.01060  0.01260  1478 GLY A O   
300  N  N   . GLY A 20  ? 0.18090 0.23600 0.21380 -0.03310 0.01060  0.01920  1479 GLY A N   
301  C  CA  . GLY A 20  ? 0.17070 0.22610 0.20340 -0.02780 0.00650  0.02080  1479 GLY A CA  
302  C  C   . GLY A 20  ? 0.16150 0.21320 0.20480 -0.03000 -0.00110 0.02440  1479 GLY A C   
303  O  O   . GLY A 20  ? 0.15640 0.20610 0.20800 -0.03670 -0.00610 0.01560  1479 GLY A O   
307  N  N   . THR A 21  ? 0.16970 0.20830 0.20000 -0.01740 0.01620  0.03630  1480 THR A N   
308  C  CA  . THR A 21  ? 0.16920 0.20790 0.19200 -0.02500 0.03040  0.03120  1480 THR A CA  
309  C  C   . THR A 21  ? 0.16730 0.20340 0.18520 -0.02820 0.02310  0.02090  1480 THR A C   
310  O  O   . THR A 21  ? 0.17770 0.20470 0.20860 -0.02500 0.00070  0.00180  1480 THR A O   
311  C  CB  . THR A 21  ? 0.18360 0.21220 0.21560 -0.03090 0.02620  0.03430  1480 THR A CB  
312  O  OG1 . THR A 21  ? 0.21110 0.21680 0.25650 -0.03300 0.03710  0.04660  1480 THR A OG1 
313  C  CG2 . THR A 21  ? 0.19530 0.21490 0.22850 -0.01940 0.01330  0.02380  1480 THR A CG2 
321  N  N   . HIS A 22  ? 0.15800 0.20450 0.19800 -0.02830 0.00800  0.02550  1481 HIS A N   
322  C  CA  . HIS A 22  ? 0.15500 0.20970 0.20700 -0.01980 0.00750  0.01690  1481 HIS A CA  
323  C  C   . HIS A 22  ? 0.15370 0.20210 0.20350 -0.02100 0.00150  0.00760  1481 HIS A C   
324  O  O   . HIS A 22  ? 0.16210 0.20680 0.20860 -0.03060 -0.00520 0.00410  1481 HIS A O   
325  C  CB  . HIS A 22  ? 0.14900 0.22390 0.21990 -0.02400 0.01300  0.02210  1481 HIS A CB  
326  C  CG  . HIS A 22  ? 0.14790 0.23280 0.21500 -0.03020 0.02270  0.02740  1481 HIS A CG  
327  N  ND1 . HIS A 22  ? 0.17460 0.23800 0.21710 -0.02910 0.03950  0.01840  1481 HIS A ND1 
328  C  CD2 . HIS A 22  ? 0.13680 0.23900 0.22320 -0.02830 0.01910  0.02860  1481 HIS A CD2 
329  C  CE1 . HIS A 22  ? 0.16960 0.24020 0.21320 -0.02920 0.03570  0.02150  1481 HIS A CE1 
330  N  NE2 . HIS A 22  ? 0.15340 0.24110 0.22100 -0.02100 0.03590  0.02840  1481 HIS A NE2 
338  N  N   . LYS A 23  ? 0.14000 0.18570 0.18620 -0.01230 0.01990  0.00390  1482 LYS A N   
339  C  CA  . LYS A 23  ? 0.14750 0.17580 0.17970 -0.00560 0.01510  0.00020  1482 LYS A CA  
340  C  C   . LYS A 23  ? 0.15270 0.16570 0.17460 -0.00910 0.01830  0.00470  1482 LYS A C   
341  O  O   . LYS A 23  ? 0.13780 0.16190 0.16860 -0.01740 0.01000  -0.00250 1482 LYS A O   
342  C  CB  . LYS A 23  ? 0.14410 0.17870 0.18090 -0.00100 0.00270  -0.01240 1482 LYS A CB  
343  C  CG  . LYS A 23  ? 0.15450 0.17920 0.17580 0.00110  -0.00140 -0.01680 1482 LYS A CG  
344  C  CD  . LYS A 23  ? 0.17600 0.18080 0.16700 -0.00160 0.00050  -0.02300 1482 LYS A CD  
345  C  CE  . LYS A 23  ? 0.18440 0.18320 0.15910 0.00000  -0.00160 -0.01810 1482 LYS A CE  
346  N  NZ  . LYS A 23  ? 0.19060 0.18660 0.16940 0.00230  -0.00900 -0.01030 1482 LYS A NZ  
360  N  N   . GLU A 24  ? 0.14710 0.15990 0.18800 -0.01080 0.03580  0.01580  1483 GLU A N   
361  C  CA  . GLU A 24  ? 0.13690 0.14610 0.17570 -0.01790 0.03000  -0.00020 1483 GLU A CA  
362  C  C   . GLU A 24  ? 0.13420 0.16120 0.16600 -0.02330 0.03510  -0.00660 1483 GLU A C   
363  O  O   . GLU A 24  ? 0.12930 0.15280 0.18790 -0.01490 0.03460  0.00010  1483 GLU A O   
364  C  CB  . GLU A 24  ? 0.13530 0.13930 0.18000 -0.02460 0.01660  0.00730  1483 GLU A CB  
365  C  CG  . GLU A 24  ? 0.12310 0.13640 0.16450 -0.02160 0.00980  0.00850  1483 GLU A CG  
366  C  CD  . GLU A 24  ? 0.11220 0.14090 0.16930 -0.01020 0.00380  0.00760  1483 GLU A CD  
367  O  OE1 . GLU A 24  ? 0.13420 0.14820 0.16980 -0.01200 0.00840  -0.00790 1483 GLU A OE1 
368  O  OE2 . GLU A 24  ? 0.12520 0.14650 0.18580 -0.01450 0.00680  0.01000  1483 GLU A OE2 
375  N  N   . ASP A 25  ? 0.37650 0.36710 0.37870 -0.00090 0.00050  -0.00020 1484 ASP A N   
376  C  CA  . ASP A 25  ? 0.38050 0.38020 0.38060 -0.00000 0.00010  -0.00000 1484 ASP A CA  
377  C  C   . ASP A 25  ? 0.37710 0.36770 0.37890 -0.00020 0.00000  0.00010  1484 ASP A C   
378  O  O   . ASP A 25  ? 0.38010 0.38000 0.38050 -0.00010 -0.00000 -0.00010 1484 ASP A O   
379  C  CB  . ASP A 25  ? 0.38050 0.38060 0.38060 0.00000  0.00000  0.00000  1484 ASP A CB  
380  C  CG  . ASP A 25  ? 0.38060 0.38060 0.38080 0.00010  -0.00010 0.00000  1484 ASP A CG  
381  O  OD1 . ASP A 25  ? 0.38030 0.38030 0.38050 -0.00010 -0.00010 0.00000  1484 ASP A OD1 
382  O  OD2 . ASP A 25  ? 0.38050 0.38050 0.38070 -0.00000 0.00010  0.00000  1484 ASP A OD2 
387  N  N   . PHE A 26  ? 0.16030 0.16260 0.18540 -0.00930 0.01530  0.01030  1485 PHE A N   
388  C  CA  . PHE A 26  ? 0.16090 0.15450 0.17270 -0.00950 0.02020  0.01180  1485 PHE A CA  
389  C  C   . PHE A 26  ? 0.15490 0.14740 0.18740 -0.01130 0.02060  0.00560  1485 PHE A C   
390  O  O   . PHE A 26  ? 0.14900 0.14410 0.19620 -0.01070 0.02080  -0.00020 1485 PHE A O   
391  C  CB  . PHE A 26  ? 0.18670 0.16530 0.17000 -0.00290 0.00090  0.01470  1485 PHE A CB  
392  C  CG  . PHE A 26  ? 0.20310 0.17860 0.20020 0.00550  -0.02220 0.00960  1485 PHE A CG  
393  C  CD1 . PHE A 26  ? 0.25300 0.18520 0.21760 -0.00050 -0.02550 0.00810  1485 PHE A CD1 
394  C  CD2 . PHE A 26  ? 0.20040 0.18570 0.22730 0.01160  -0.01800 0.00270  1485 PHE A CD2 
395  C  CE1 . PHE A 26  ? 0.26900 0.18950 0.22640 0.00400  -0.01880 0.00680  1485 PHE A CE1 
396  C  CE2 . PHE A 26  ? 0.22450 0.19200 0.23820 0.02170  -0.00610 0.00000  1485 PHE A CE2 
397  C  CZ  . PHE A 26  ? 0.25680 0.18770 0.22740 0.01830  -0.01080 0.00130  1485 PHE A CZ  
407  N  N   . ALA A 27  ? 0.14720 0.14490 0.19380 -0.01050 0.02770  -0.00160 1486 ALA A N   
408  C  CA  . ALA A 27  ? 0.14730 0.14800 0.19950 -0.02410 0.02660  -0.00750 1486 ALA A CA  
409  C  C   . ALA A 27  ? 0.14900 0.14810 0.20810 -0.02700 0.01910  -0.01540 1486 ALA A C   
410  O  O   . ALA A 27  ? 0.16810 0.15150 0.22710 -0.01460 0.00770  -0.02220 1486 ALA A O   
411  C  CB  . ALA A 27  ? 0.16610 0.15030 0.22320 -0.02670 0.01780  -0.00300 1486 ALA A CB  
417  N  N   . SER A 28  ? 0.14240 0.15190 0.20870 -0.02830 0.00640  -0.01430 1487 SER A N   
418  C  CA  . SER A 28  ? 0.13500 0.15770 0.18590 -0.01820 0.00800  -0.01650 1487 SER A CA  
419  C  C   . SER A 28  ? 0.12790 0.15350 0.16280 -0.01480 0.01680  -0.00980 1487 SER A C   
420  O  O   . SER A 28  ? 0.14270 0.15380 0.16910 -0.01600 0.00400  -0.01750 1487 SER A O   
421  C  CB  . SER A 28  ? 0.13060 0.16260 0.19360 -0.02090 0.00290  -0.01530 1487 SER A CB  
422  O  OG  . SER A 28  ? 0.13380 0.16740 0.19640 -0.02510 0.00630  -0.01800 1487 SER A OG  
428  N  N   . GLY A 29  ? 0.13530 0.14570 0.16300 -0.02150 0.01440  -0.00650 1488 GLY A N   
429  C  CA  . GLY A 29  ? 0.12640 0.13760 0.15160 -0.01120 0.01650  -0.00180 1488 GLY A CA  
430  C  C   . GLY A 29  ? 0.12390 0.13060 0.15540 -0.01140 0.01040  -0.00690 1488 GLY A C   
431  O  O   . GLY A 29  ? 0.12950 0.12760 0.16660 -0.01350 0.02170  -0.01880 1488 GLY A O   
435  N  N   . THR A 30  ? 0.13350 0.12740 0.16890 -0.01650 0.00890  -0.02000 1489 THR A N   
436  C  CA  . THR A 30  ? 0.14250 0.12550 0.18350 -0.01540 0.01450  -0.01730 1489 THR A CA  
437  C  C   . THR A 30  ? 0.14980 0.12770 0.19080 -0.01340 0.01210  -0.02110 1489 THR A C   
438  O  O   . THR A 30  ? 0.13970 0.13040 0.18770 -0.01280 0.00200  -0.02440 1489 THR A O   
439  C  CB  . THR A 30  ? 0.13780 0.11970 0.19740 -0.01600 0.00500  -0.01470 1489 THR A CB  
440  O  OG1 . THR A 30  ? 0.14220 0.11950 0.20980 -0.01840 0.00800  -0.00770 1489 THR A OG1 
441  C  CG2 . THR A 30  ? 0.13890 0.11960 0.22500 -0.01520 0.00040  -0.01780 1489 THR A CG2 
449  N  N   . ALA A 31  ? 0.14480 0.13300 0.18600 -0.01480 0.00880  -0.03210 1490 ALA A N   
450  C  CA  . ALA A 31  ? 0.15140 0.13290 0.17830 -0.02720 -0.00470 -0.03220 1490 ALA A CA  
451  C  C   . ALA A 31  ? 0.13760 0.13570 0.16740 -0.02810 -0.00190 -0.02800 1490 ALA A C   
452  O  O   . ALA A 31  ? 0.14050 0.14050 0.17480 -0.03220 -0.00600 -0.03210 1490 ALA A O   
453  C  CB  . ALA A 31  ? 0.16440 0.13490 0.18970 -0.03620 -0.00850 -0.03680 1490 ALA A CB  
459  N  N   . ALA A 32  ? 0.13000 0.13710 0.16950 -0.02290 0.01250  -0.01800 1491 ALA A N   
460  C  CA  . ALA A 32  ? 0.12670 0.14560 0.16300 -0.01710 0.00310  -0.01720 1491 ALA A CA  
461  C  C   . ALA A 32  ? 0.12370 0.14240 0.14800 -0.00840 0.00620  -0.02260 1491 ALA A C   
462  O  O   . ALA A 32  ? 0.13320 0.14590 0.16180 -0.01080 -0.00910 -0.01590 1491 ALA A O   
463  C  CB  . ALA A 32  ? 0.12690 0.14920 0.18440 -0.01900 -0.01270 -0.02000 1491 ALA A CB  
469  N  N   . ALA A 33  ? 0.12780 0.14360 0.15280 -0.01230 0.01220  -0.02380 1492 ALA A N   
470  C  CA  . ALA A 33  ? 0.11710 0.14210 0.15230 -0.00980 0.00290  -0.02770 1492 ALA A CA  
471  C  C   . ALA A 33  ? 0.12420 0.13670 0.14710 -0.01060 -0.00730 -0.03150 1492 ALA A C   
472  O  O   . ALA A 33  ? 0.13330 0.14030 0.15420 -0.01040 -0.00830 -0.03030 1492 ALA A O   
473  C  CB  . ALA A 33  ? 0.11030 0.14340 0.16410 -0.01790 0.02090  -0.04250 1492 ALA A CB  
479  N  N   . LEU A 34  ? 0.14380 0.13240 0.14940 -0.00890 0.01200  -0.03380 1493 LEU A N   
480  C  CA  . LEU A 34  ? 0.16200 0.13370 0.17070 -0.01660 0.01400  -0.03460 1493 LEU A CA  
481  C  C   . LEU A 34  ? 0.15810 0.13990 0.17560 -0.01550 0.00850  -0.03720 1493 LEU A C   
482  O  O   . LEU A 34  ? 0.15470 0.13940 0.17300 -0.00890 0.02050  -0.03400 1493 LEU A O   
483  C  CB  . LEU A 34  ? 0.17270 0.13430 0.18760 -0.01930 0.00630  -0.01950 1493 LEU A CB  
484  C  CG  . LEU A 34  ? 0.16790 0.13880 0.20070 -0.01080 0.01230  -0.01530 1493 LEU A CG  
485  C  CD1 . LEU A 34  ? 0.16630 0.14070 0.20400 -0.00750 0.01470  -0.00410 1493 LEU A CD1 
486  C  CD2 . LEU A 34  ? 0.16120 0.14180 0.20300 -0.01210 0.00710  -0.01630 1493 LEU A CD2 
498  N  N   . ALA A 35  ? 0.15660 0.14360 0.17160 -0.00840 -0.00290 -0.04520 1494 ALA A N   
499  C  CA  . ALA A 35  ? 0.15710 0.14800 0.18450 -0.01890 -0.00460 -0.02990 1494 ALA A CA  
500  C  C   . ALA A 35  ? 0.16540 0.15390 0.16970 -0.02060 0.00200  -0.02850 1494 ALA A C   
501  O  O   . ALA A 35  ? 0.19850 0.17190 0.19230 -0.03340 -0.00210 -0.02820 1494 ALA A O   
502  C  CB  . ALA A 35  ? 0.15460 0.14900 0.19910 -0.02250 -0.00070 -0.02990 1494 ALA A CB  
508  N  N   . GLY A 36  ? 0.14440 0.14640 0.17330 -0.01580 -0.00680 -0.02970 1495 GLY A N   
509  C  CA  . GLY A 36  ? 0.14780 0.14220 0.15620 -0.01510 -0.00530 -0.02800 1495 GLY A CA  
510  C  C   . GLY A 36  ? 0.14630 0.13590 0.16630 -0.00820 -0.00020 -0.02780 1495 GLY A C   
511  O  O   . GLY A 36  ? 0.15010 0.13500 0.18280 -0.00670 0.01760  -0.00950 1495 GLY A O   
515  N  N   . GLY A 37  ? 0.14190 0.14170 0.17680 0.00100  0.00410  -0.03340 1496 GLY A N   
516  C  CA  . GLY A 37  ? 0.14270 0.14280 0.18560 -0.00260 0.00100  -0.02810 1496 GLY A CA  
517  C  C   . GLY A 37  ? 0.14450 0.13370 0.17100 -0.01170 0.00000  -0.03290 1496 GLY A C   
518  O  O   . GLY A 37  ? 0.16740 0.13900 0.17240 -0.02420 0.00120  -0.03180 1496 GLY A O   
522  N  N   . ILE A 38  ? 0.13300 0.12480 0.16260 -0.01000 0.00430  -0.03010 1497 ILE A N   
523  C  CA  . ILE A 38  ? 0.14090 0.12580 0.15660 -0.01430 0.00000  -0.03440 1497 ILE A CA  
524  C  C   . ILE A 38  ? 0.12950 0.12530 0.16550 -0.01660 -0.00790 -0.02780 1497 ILE A C   
525  O  O   . ILE A 38  ? 0.12570 0.13390 0.18810 -0.02020 -0.00700 -0.01830 1497 ILE A O   
526  C  CB  . ILE A 38  ? 0.15500 0.13240 0.16460 -0.01380 0.00540  -0.03360 1497 ILE A CB  
527  C  CG1 . ILE A 38  ? 0.19400 0.14410 0.19840 -0.01820 0.01050  -0.02480 1497 ILE A CG1 
528  C  CG2 . ILE A 38  ? 0.15010 0.13170 0.14970 -0.00780 0.01740  -0.03660 1497 ILE A CG2 
529  C  CD1 . ILE A 38  ? 0.22320 0.15320 0.24970 -0.01030 0.03440  -0.01260 1497 ILE A CD1 
541  N  N   . THR A 39  ? 0.12300 0.12170 0.17540 -0.01630 -0.01170 -0.02340 1498 THR A N   
542  C  CA  . THR A 39  ? 0.11570 0.12110 0.16140 -0.01690 0.00450  -0.00650 1498 THR A CA  
543  C  C   . THR A 39  ? 0.12180 0.11270 0.16810 -0.02040 0.01780  -0.01250 1498 THR A C   
544  O  O   . THR A 39  ? 0.13240 0.10900 0.17320 -0.01090 0.01540  -0.00850 1498 THR A O   
545  C  CB  . THR A 39  ? 0.13390 0.12720 0.16440 -0.01090 -0.00060 -0.01060 1498 THR A CB  
546  O  OG1 . THR A 39  ? 0.12940 0.13520 0.17730 -0.01040 0.02150  -0.00660 1498 THR A OG1 
547  C  CG2 . THR A 39  ? 0.15320 0.12900 0.17060 -0.00960 0.00970  -0.02270 1498 THR A CG2 
555  N  N   . MET A 40  ? 0.12170 0.10900 0.14500 -0.01260 0.01830  -0.01260 1499 MET A N   
556  C  CA  . MET A 40  ? 0.11910 0.10930 0.14470 -0.00420 0.02390  -0.01140 1499 MET A CA  
557  C  C   . MET A 40  ? 0.11790 0.10740 0.14670 -0.00330 0.02150  -0.00310 1499 MET A C   
558  O  O   . MET A 40  ? 0.12010 0.11130 0.16480 -0.01030 0.00750  0.00720  1499 MET A O   
559  C  CB  . MET A 40  ? 0.11530 0.11380 0.15770 -0.00020 0.03160  0.00340  1499 MET A CB  
560  C  CG  . MET A 40  ? 0.11530 0.12460 0.17730 0.00650  0.00460  0.00550  1499 MET A CG  
561  S  SD  . MET A 40  ? 0.12750 0.12650 0.17530 -0.00970 0.00500  -0.00320 1499 MET A SD  
562  C  CE  . MET A 40  ? 0.12260 0.13670 0.18180 -0.00310 0.01980  -0.01290 1499 MET A CE  
572  N  N   . VAL A 41  ? 0.12530 0.10770 0.14340 -0.00360 0.00780  -0.01520 1500 VAL A N   
573  C  CA  . VAL A 41  ? 0.12170 0.11530 0.15270 -0.00460 0.02000  -0.00400 1500 VAL A CA  
574  C  C   . VAL A 41  ? 0.13370 0.11400 0.14270 -0.00040 0.01400  -0.00230 1500 VAL A C   
575  O  O   . VAL A 41  ? 0.15370 0.11530 0.14490 -0.00710 0.00230  0.00230  1500 VAL A O   
576  C  CB  . VAL A 41  ? 0.12560 0.12660 0.17110 -0.00460 0.01370  -0.00160 1500 VAL A CB  
577  C  CG1 . VAL A 41  ? 0.13980 0.13030 0.16880 -0.00370 -0.00250 0.00600  1500 VAL A CG1 
578  C  CG2 . VAL A 41  ? 0.12630 0.13320 0.18560 -0.01060 0.00330  -0.00330 1500 VAL A CG2 
588  N  N   . CYS A 42  ? 0.13410 0.11270 0.13610 0.00130  0.02210  -0.00840 1501 CYS A N   
589  C  CA  . CYS A 42  ? 0.12240 0.11640 0.12670 -0.00350 0.01770  0.00540  1501 CYS A CA  
590  C  C   . CYS A 42  ? 0.11430 0.11850 0.12690 -0.01340 0.00140  0.01010  1501 CYS A C   
591  O  O   . CYS A 42  ? 0.11060 0.11880 0.12580 -0.00330 -0.00430 0.01140  1501 CYS A O   
592  C  CB  . CYS A 42  ? 0.11100 0.12590 0.16110 0.00230  0.01640  0.00550  1501 CYS A CB  
593  S  SG  . CYS A 42  ? 0.11670 0.12390 0.19290 -0.00540 0.01790  0.00440  1501 CYS A SG  
599  N  N   . ALA A 43  ? 0.11550 0.12890 0.14150 -0.01220 0.02270  0.01400  1502 ALA A N   
600  C  CA  . ALA A 43  ? 0.11730 0.12940 0.13960 -0.01170 0.00700  0.00410  1502 ALA A CA  
601  C  C   . ALA A 43  ? 0.12530 0.12140 0.12550 -0.00850 -0.00190 0.00770  1502 ALA A C   
602  O  O   . ALA A 43  ? 0.12690 0.11790 0.14850 -0.00380 -0.01610 0.00700  1502 ALA A O   
603  C  CB  . ALA A 43  ? 0.13320 0.13320 0.16790 -0.00200 0.00600  -0.00590 1502 ALA A CB  
609  N  N   . MET A 44  ? 0.12530 0.12560 0.10440 -0.00470 -0.00900 -0.00320 1503 MET A N   
610  C  CA  . MET A 44  ? 0.11580 0.13160 0.10160 -0.00380 -0.01410 0.00810  1503 MET A CA  
611  C  C   . MET A 44  ? 0.12470 0.13290 0.12090 0.00160  -0.01680 0.00590  1503 MET A C   
612  O  O   . MET A 44  ? 0.13710 0.12900 0.15050 -0.01190 -0.00190 -0.00760 1503 MET A O   
613  C  CB  . MET A 44  ? 0.11220 0.13720 0.12950 -0.00230 -0.01540 0.00980  1503 MET A CB  
614  C  CG  . MET A 44  ? 0.13980 0.13840 0.13020 -0.00100 -0.00600 0.01300  1503 MET A CG  
615  S  SD  . MET A 44  ? 0.13950 0.13560 0.14540 -0.01640 -0.00000 0.00280  1503 MET A SD  
616  C  CE  . MET A 44  ? 0.14150 0.14150 0.15160 -0.02000 -0.00160 0.01280  1503 MET A CE  
626  N  N   . PRO A 45  ? 0.12930 0.13580 0.10790 0.00020  -0.00360 0.00030  1504 PRO A N   
627  C  CA  . PRO A 45  ? 0.14140 0.14140 0.11480 0.00140  -0.00330 0.00260  1504 PRO A CA  
628  C  C   . PRO A 45  ? 0.14400 0.15370 0.12740 -0.00760 -0.00620 0.00830  1504 PRO A C   
629  O  O   . PRO A 45  ? 0.16050 0.15520 0.12400 -0.00400 0.00830  0.00810  1504 PRO A O   
630  C  CB  . PRO A 45  ? 0.14510 0.13840 0.14180 -0.00030 -0.00120 0.00360  1504 PRO A CB  
631  C  CG  . PRO A 45  ? 0.13690 0.13770 0.13710 0.00470  -0.00240 -0.00180 1504 PRO A CG  
632  C  CD  . PRO A 45  ? 0.13580 0.13640 0.12130 0.00030  -0.00990 -0.00370 1504 PRO A CD  
640  N  N   . ASN A 46  ? 0.12990 0.16210 0.14130 -0.00510 0.00510  0.00750  1505 ASN A N   
641  C  CA  . ASN A 46  ? 0.13580 0.17350 0.14700 -0.00120 0.00790  0.00880  1505 ASN A CA  
642  C  C   . ASN A 46  ? 0.13570 0.18760 0.16560 -0.00830 0.01270  0.01260  1505 ASN A C   
643  O  O   . ASN A 46  ? 0.14260 0.19300 0.16760 -0.00610 0.01560  0.00480  1505 ASN A O   
644  C  CB  . ASN A 46  ? 0.14570 0.17370 0.15270 0.00700  0.01240  0.01080  1505 ASN A CB  
645  C  CG  . ASN A 46  ? 0.15540 0.18110 0.15560 0.02090  0.01880  0.01480  1505 ASN A CG  
646  O  OD1 . ASN A 46  ? 0.15920 0.18010 0.13170 0.01650  0.02150  0.00700  1505 ASN A OD1 
647  N  ND2 . ASN A 46  ? 0.18120 0.18820 0.17640 0.03840  0.01280  0.01630  1505 ASN A ND2 
654  N  N   . THR A 47  ? 0.12510 0.19420 0.18650 -0.01630 0.00540  0.02110  1506 THR A N   
655  C  CA  . THR A 47  ? 0.15350 0.20680 0.17320 -0.02480 0.00620  0.02970  1506 THR A CA  
656  C  C   . THR A 47  ? 0.17000 0.22830 0.16880 -0.03260 0.01690  0.02780  1506 THR A C   
657  O  O   . THR A 47  ? 0.16760 0.23160 0.16800 -0.02830 0.00620  0.01570  1506 THR A O   
658  C  CB  . THR A 47  ? 0.16670 0.19560 0.16790 -0.02800 -0.01000 0.02710  1506 THR A CB  
659  O  OG1 . THR A 47  ? 0.17160 0.18830 0.18310 -0.02440 -0.02140 0.02380  1506 THR A OG1 
660  C  CG2 . THR A 47  ? 0.17300 0.19370 0.18630 -0.03120 0.00470  0.02310  1506 THR A CG2 
668  N  N   . ARG A 48  ? 0.18780 0.24720 0.18590 -0.04300 0.02680  0.02530  1507 ARG A N   
669  C  CA  . ARG A 48  ? 0.21310 0.26340 0.23500 -0.05250 0.01880  0.02080  1507 ARG A CA  
670  C  C   . ARG A 48  ? 0.21660 0.26720 0.21700 -0.06910 0.02190  0.02000  1507 ARG A C   
671  O  O   . ARG A 48  ? 0.22850 0.26590 0.22120 -0.08310 0.01960  0.01410  1507 ARG A O   
672  C  CB  . ARG A 48  ? 0.22940 0.26930 0.29190 -0.05110 0.01630  0.01540  1507 ARG A CB  
675  N  N   . PRO A 49  ? 0.22200 0.26670 0.20340 -0.06020 0.01250  0.02020  1508 PRO A N   
676  C  CA  . PRO A 49  ? 0.21970 0.26050 0.20190 -0.05010 0.01990  0.01620  1508 PRO A CA  
677  C  C   . PRO A 49  ? 0.19130 0.24210 0.17240 -0.03630 0.02180  0.00890  1508 PRO A C   
678  O  O   . PRO A 49  ? 0.19280 0.24090 0.18170 -0.03150 0.01770  0.02110  1508 PRO A O   
679  C  CB  . PRO A 49  ? 0.24370 0.27070 0.22460 -0.04880 0.01980  0.01500  1508 PRO A CB  
680  C  CG  . PRO A 49  ? 0.24730 0.27610 0.22840 -0.04950 0.01830  0.01910  1508 PRO A CG  
681  C  CD  . PRO A 49  ? 0.23970 0.27380 0.21650 -0.05900 0.01350  0.02190  1508 PRO A CD  
689  N  N   . PRO A 50  ? 0.17320 0.22600 0.17010 -0.02470 0.01000  -0.00380 1509 PRO A N   
690  C  CA  . PRO A 50  ? 0.17280 0.21090 0.15660 -0.01980 -0.00210 0.00110  1509 PRO A CA  
691  C  C   . PRO A 50  ? 0.16920 0.19750 0.14460 -0.01510 0.00580  0.01190  1509 PRO A C   
692  O  O   . PRO A 50  ? 0.17100 0.19710 0.15700 -0.02110 0.00310  0.00220  1509 PRO A O   
693  C  CB  . PRO A 50  ? 0.18190 0.21360 0.17370 -0.01510 -0.01050 -0.00580 1509 PRO A CB  
694  C  CG  . PRO A 50  ? 0.18780 0.21620 0.19540 -0.01280 0.00090  -0.01020 1509 PRO A CG  
695  C  CD  . PRO A 50  ? 0.17370 0.22370 0.19350 -0.01870 0.00700  -0.00860 1509 PRO A CD  
703  N  N   . ILE A 51  ? 0.15930 0.18830 0.15190 -0.01420 0.01300  0.02400  1510 ILE A N   
704  C  CA  . ILE A 51  ? 0.15330 0.18000 0.15640 -0.02100 0.00940  0.02670  1510 ILE A CA  
705  C  C   . ILE A 51  ? 0.16930 0.17670 0.15410 -0.02700 0.00340  0.02060  1510 ILE A C   
706  O  O   . ILE A 51  ? 0.19030 0.17010 0.15930 -0.02680 0.01540  0.03370  1510 ILE A O   
707  C  CB  . ILE A 51  ? 0.15020 0.18230 0.16390 -0.01310 0.00690  0.03440  1510 ILE A CB  
708  C  CG1 . ILE A 51  ? 0.16230 0.18380 0.18040 -0.00280 0.00810  0.03190  1510 ILE A CG1 
709  C  CG2 . ILE A 51  ? 0.16290 0.18220 0.15510 -0.01210 0.00540  0.03070  1510 ILE A CG2 
710  C  CD1 . ILE A 51  ? 0.16620 0.18610 0.19810 -0.00810 0.01640  0.02950  1510 ILE A CD1 
722  N  N   . ILE A 52  ? 0.17170 0.18300 0.17020 -0.04220 0.01460  0.02390  1511 ILE A N   
723  C  CA  . ILE A 52  ? 0.19730 0.19070 0.18700 -0.04480 0.01350  0.02030  1511 ILE A CA  
724  C  C   . ILE A 52  ? 0.22710 0.18440 0.17530 -0.05600 0.00280  0.03430  1511 ILE A C   
725  O  O   . ILE A 52  ? 0.24540 0.17600 0.19200 -0.06070 -0.01430 0.02310  1511 ILE A O   
726  C  CB  . ILE A 52  ? 0.20420 0.20450 0.22030 -0.04440 0.01810  0.00780  1511 ILE A CB  
727  C  CG1 . ILE A 52  ? 0.22750 0.21800 0.23260 -0.03640 0.01500  -0.00400 1511 ILE A CG1 
728  C  CG2 . ILE A 52  ? 0.20640 0.20680 0.23980 -0.04880 0.01160  0.01190  1511 ILE A CG2 
729  C  CD1 . ILE A 52  ? 0.24490 0.23270 0.26640 -0.03090 0.01370  -0.01230 1511 ILE A CD1 
741  N  N   A ASP A 53  ? 0.23790 0.18660 0.17120 -0.05470 0.00070  0.03920  1512 ASP A N   
742  N  N   B ASP A 53  ? 0.23570 0.18500 0.16870 -0.05480 0.00200  0.04010  1512 ASP A N   
743  C  CA  A ASP A 53  ? 0.24660 0.19090 0.18780 -0.05390 -0.00570 0.03970  1512 ASP A CA  
744  C  CA  B ASP A 53  ? 0.24310 0.18950 0.19120 -0.05480 -0.00330 0.03950  1512 ASP A CA  
745  C  C   A ASP A 53  ? 0.23670 0.19070 0.18400 -0.05620 -0.01880 0.04070  1512 ASP A C   
746  C  C   B ASP A 53  ? 0.23390 0.18750 0.18170 -0.05850 -0.01900 0.04200  1512 ASP A C   
747  O  O   A ASP A 53  ? 0.22960 0.18820 0.19360 -0.06340 -0.01670 0.03980  1512 ASP A O   
748  O  O   B ASP A 53  ? 0.22670 0.18200 0.19360 -0.06880 -0.01530 0.04170  1512 ASP A O   
749  C  CB  A ASP A 53  ? 0.26340 0.19480 0.20460 -0.04910 0.00310  0.04170  1512 ASP A CB  
750  C  CB  B ASP A 53  ? 0.26430 0.19670 0.21930 -0.04580 0.00660  0.03840  1512 ASP A CB  
751  C  CG  A ASP A 53  ? 0.27010 0.19900 0.21890 -0.04600 0.01650  0.04240  1512 ASP A CG  
752  C  CG  B ASP A 53  ? 0.26890 0.20430 0.24300 -0.03660 0.01620  0.03650  1512 ASP A CG  
753  O  OD1 A ASP A 53  ? 0.26820 0.19870 0.21700 -0.04310 0.01880  0.04670  1512 ASP A OD1 
754  O  OD1 B ASP A 53  ? 0.26360 0.20130 0.23910 -0.02940 0.02020  0.03710  1512 ASP A OD1 
755  O  OD2 A ASP A 53  ? 0.27710 0.20140 0.22720 -0.04810 0.02570  0.03930  1512 ASP A OD2 
756  O  OD2 B ASP A 53  ? 0.27840 0.21020 0.26060 -0.03240 0.01400  0.03540  1512 ASP A OD2 
765  N  N   . ALA A 54  ? 0.23850 0.19320 0.18910 -0.04960 -0.02380 0.03930  1513 ALA A N   
766  C  CA  . ALA A 54  ? 0.23420 0.19400 0.18760 -0.03930 -0.01910 0.04090  1513 ALA A CA  
767  C  C   . ALA A 54  ? 0.23820 0.18910 0.18910 -0.03450 -0.00490 0.05190  1513 ALA A C   
768  O  O   . ALA A 54  ? 0.23120 0.19520 0.19820 -0.02570 -0.00850 0.05710  1513 ALA A O   
769  C  CB  . ALA A 54  ? 0.23860 0.20180 0.18810 -0.02840 -0.00890 0.04250  1513 ALA A CB  
776  N  N   . PRO A 55  ? 0.24470 0.18240 0.19410 -0.03410 0.01140  0.05010  1514 PRO A N   
777  C  CA  . PRO A 55  ? 0.24920 0.17700 0.20060 -0.03080 0.01880  0.05180  1514 PRO A CA  
778  C  C   . PRO A 55  ? 0.22930 0.16600 0.19690 -0.02510 0.02280  0.03960  1514 PRO A C   
779  O  O   . PRO A 55  ? 0.20600 0.15640 0.20290 -0.02510 0.03800  0.02830  1514 PRO A O   
780  C  CB  . PRO A 55  ? 0.26930 0.18410 0.21380 -0.03390 0.01360  0.05780  1514 PRO A CB  
781  C  CG  . PRO A 55  ? 0.27110 0.19050 0.22770 -0.02980 0.01190  0.05360  1514 PRO A CG  
782  C  CD  . PRO A 55  ? 0.26320 0.18500 0.20200 -0.03150 0.01520  0.05940  1514 PRO A CD  
790  N  N   . ALA A 56  ? 0.21850 0.15830 0.17880 -0.03010 0.02080  0.04380  1515 ALA A N   
791  C  CA  . ALA A 56  ? 0.21030 0.15250 0.17470 -0.02040 0.01040  0.03590  1515 ALA A CA  
792  C  C   . ALA A 56  ? 0.19870 0.14800 0.15740 -0.01590 0.01510  0.03890  1515 ALA A C   
793  O  O   . ALA A 56  ? 0.18560 0.14280 0.17670 -0.00860 0.01620  0.03620  1515 ALA A O   
794  C  CB  . ALA A 56  ? 0.20950 0.15230 0.18080 -0.01900 0.00310  0.02900  1515 ALA A CB  
800  N  N   . LEU A 57  ? 0.20490 0.15630 0.14700 -0.02500 0.01390  0.03810  1516 LEU A N   
801  C  CA  . LEU A 57  ? 0.18730 0.16130 0.17460 -0.03120 0.02130  0.03720  1516 LEU A CA  
802  C  C   . LEU A 57  ? 0.18920 0.15750 0.19120 -0.02630 0.01300  0.03600  1516 LEU A C   
803  O  O   . LEU A 57  ? 0.19580 0.14990 0.20600 -0.02560 0.01700  0.03440  1516 LEU A O   
804  C  CB  . LEU A 57  ? 0.18840 0.17630 0.18830 -0.03980 0.02110  0.03040  1516 LEU A CB  
805  C  CG  . LEU A 57  ? 0.20260 0.18750 0.20780 -0.04730 0.02110  0.02780  1516 LEU A CG  
806  C  CD1 . LEU A 57  ? 0.20250 0.18780 0.20420 -0.05480 0.00630  0.03130  1516 LEU A CD1 
807  C  CD2 . LEU A 57  ? 0.20270 0.19400 0.23630 -0.04260 0.03380  0.02530  1516 LEU A CD2 
819  N  N   . ALA A 58  ? 0.19390 0.16130 0.18820 -0.02910 0.00690  0.03190  1517 ALA A N   
820  C  CA  . ALA A 58  ? 0.20340 0.15990 0.18330 -0.03430 -0.00380 0.03810  1517 ALA A CA  
821  C  C   . ALA A 58  ? 0.18540 0.15440 0.19800 -0.04150 0.01750  0.03830  1517 ALA A C   
822  O  O   . ALA A 58  ? 0.16970 0.15630 0.21120 -0.03900 0.01690  0.01830  1517 ALA A O   
823  C  CB  . ALA A 58  ? 0.22960 0.16380 0.17580 -0.02860 -0.01620 0.03360  1517 ALA A CB  
829  N  N   . LEU A 59  ? 0.17980 0.14430 0.19090 -0.03840 0.01780  0.05170  1518 LEU A N   
830  C  CA  . LEU A 59  ? 0.18270 0.14990 0.19440 -0.03460 0.02580  0.03070  1518 LEU A CA  
831  C  C   . LEU A 59  ? 0.17850 0.14790 0.17400 -0.02150 0.01590  0.02040  1518 LEU A C   
832  O  O   . LEU A 59  ? 0.17440 0.14190 0.17370 -0.02160 0.01810  0.01480  1518 LEU A O   
833  C  CB  . LEU A 59  ? 0.19380 0.16330 0.19420 -0.02160 0.03110  0.02530  1518 LEU A CB  
834  C  CG  . LEU A 59  ? 0.21060 0.17710 0.20400 0.00330  0.03430  0.01690  1518 LEU A CG  
835  C  CD1 . LEU A 59  ? 0.20540 0.17890 0.21210 -0.00040 0.04830  0.02390  1518 LEU A CD1 
836  C  CD2 . LEU A 59  ? 0.21460 0.18440 0.21950 0.01050  0.03300  0.01090  1518 LEU A CD2 
848  N  N   . ALA A 60  ? 0.18870 0.15050 0.17150 -0.02460 0.02310  0.02660  1519 ALA A N   
849  C  CA  . ALA A 60  ? 0.20980 0.14760 0.16110 -0.01770 0.02480  0.02110  1519 ALA A CA  
850  C  C   . ALA A 60  ? 0.19750 0.14410 0.13600 -0.02510 0.03090  0.02400  1519 ALA A C   
851  O  O   . ALA A 60  ? 0.18850 0.13710 0.15980 -0.02740 0.01550  0.02010  1519 ALA A O   
852  C  CB  . ALA A 60  ? 0.23660 0.14810 0.17970 -0.02080 0.02220  0.02130  1519 ALA A CB  
858  N  N   . GLN A 61  ? 0.19210 0.15170 0.15410 -0.02900 0.02930  0.01780  1520 GLN A N   
859  C  CA  . GLN A 61  ? 0.18350 0.16310 0.17280 -0.03040 0.02210  0.02870  1520 GLN A CA  
860  C  C   . GLN A 61  ? 0.16670 0.15250 0.16230 -0.02790 0.02000  0.02800  1520 GLN A C   
861  O  O   . GLN A 61  ? 0.16420 0.14670 0.17260 -0.02430 0.01220  0.03520  1520 GLN A O   
862  C  CB  . GLN A 61  ? 0.19840 0.19020 0.22260 -0.03620 0.00990  0.03370  1520 GLN A CB  
863  C  CG  . GLN A 61  ? 0.22920 0.22160 0.27080 -0.03110 0.00610  0.03800  1520 GLN A CG  
864  C  CD  . GLN A 61  ? 0.25380 0.24990 0.32500 -0.02800 -0.00060 0.05260  1520 GLN A CD  
865  O  OE1 . GLN A 61  ? 0.25910 0.26210 0.34720 -0.02170 -0.00950 0.05020  1520 GLN A OE1 
866  N  NE2 . GLN A 61  ? 0.27440 0.26210 0.35720 -0.02520 -0.01140 0.05690  1520 GLN A NE2 
875  N  N   . LYS A 62  ? 0.16600 0.14700 0.17880 -0.02910 0.01290  0.03260  1521 LYS A N   
876  C  CA  . LYS A 62  ? 0.17850 0.15060 0.18310 -0.02010 0.02520  0.02780  1521 LYS A CA  
877  C  C   . LYS A 62  ? 0.17070 0.14190 0.19300 -0.02050 0.03880  0.02370  1521 LYS A C   
878  O  O   . LYS A 62  ? 0.17200 0.14080 0.22470 -0.01920 0.02390  0.01290  1521 LYS A O   
879  C  CB  . LYS A 62  ? 0.19890 0.17030 0.19900 -0.02390 0.02180  0.04080  1521 LYS A CB  
880  C  CG  . LYS A 62  ? 0.22620 0.19420 0.25130 -0.02110 0.03040  0.05260  1521 LYS A CG  
881  C  CD  . LYS A 62  ? 0.25670 0.21550 0.30520 -0.02210 0.03960  0.04940  1521 LYS A CD  
882  C  CE  . LYS A 62  ? 0.25620 0.22600 0.33160 -0.02790 0.06210  0.03790  1521 LYS A CE  
883  N  NZ  . LYS A 62  ? 0.25700 0.23390 0.36510 -0.03720 0.05880  0.02670  1521 LYS A NZ  
897  N  N   . LEU A 63  ? 0.16320 0.14170 0.20360 -0.02370 0.04650  0.02910  1522 LEU A N   
898  C  CA  . LEU A 63  ? 0.16500 0.14520 0.19900 -0.01780 0.02190  0.01930  1522 LEU A CA  
899  C  C   . LEU A 63  ? 0.16360 0.13830 0.19820 -0.01460 0.01790  0.00380  1522 LEU A C   
900  O  O   . LEU A 63  ? 0.17000 0.14610 0.20560 -0.01450 0.01910  0.00680  1522 LEU A O   
901  C  CB  . LEU A 63  ? 0.17770 0.16140 0.19680 -0.00930 0.01650  0.03430  1522 LEU A CB  
902  C  CG  . LEU A 63  ? 0.19890 0.17930 0.20650 0.00440  0.02920  0.03560  1522 LEU A CG  
903  C  CD1 . LEU A 63  ? 0.21480 0.18570 0.20310 0.01580  0.03910  0.04140  1522 LEU A CD1 
904  C  CD2 . LEU A 63  ? 0.20970 0.18750 0.21520 0.00630  0.04400  0.03320  1522 LEU A CD2 
916  N  N   . ALA A 64  ? 0.17160 0.13050 0.18960 -0.02000 0.03020  0.00010  1523 ALA A N   
917  C  CA  . ALA A 64  ? 0.16290 0.13010 0.18320 -0.02280 0.03720  0.00090  1523 ALA A CA  
918  C  C   . ALA A 64  ? 0.15080 0.13450 0.17750 -0.02640 0.03930  0.00440  1523 ALA A C   
919  O  O   . ALA A 64  ? 0.14720 0.13990 0.17830 -0.01770 0.02360  0.01230  1523 ALA A O   
920  C  CB  . ALA A 64  ? 0.16650 0.12860 0.19240 -0.02990 0.03580  0.00230  1523 ALA A CB  
926  N  N   . GLU A 65  ? 0.15700 0.13450 0.21050 -0.02460 0.02590  0.00850  1524 GLU A N   
927  C  CA  . GLU A 65  ? 0.15550 0.14440 0.23360 -0.02630 0.01070  0.00400  1524 GLU A CA  
928  C  C   . GLU A 65  ? 0.15810 0.14360 0.24610 -0.02480 0.00510  -0.00310 1524 GLU A C   
929  O  O   . GLU A 65  ? 0.17780 0.15240 0.27800 -0.01810 -0.01540 -0.01610 1524 GLU A O   
930  C  CB  . GLU A 65  ? 0.16030 0.15840 0.23320 -0.03510 0.01020  0.01770  1524 GLU A CB  
931  C  CG  . GLU A 65  ? 0.16150 0.17480 0.25490 -0.04180 0.00710  0.02870  1524 GLU A CG  
932  C  CD  . GLU A 65  ? 0.18490 0.19710 0.29130 -0.04690 0.00180  0.04060  1524 GLU A CD  
933  O  OE1 . GLU A 65  ? 0.19290 0.21840 0.31870 -0.05300 -0.00520 0.04840  1524 GLU A OE1 
934  O  OE2 . GLU A 65  ? 0.19620 0.19810 0.29860 -0.03350 0.00160  0.03620  1524 GLU A OE2 
941  N  N   . ALA A 66  ? 0.15160 0.13910 0.22970 -0.02660 0.02160  0.00470  1525 ALA A N   
942  C  CA  . ALA A 66  ? 0.16760 0.14120 0.23380 -0.03190 0.01990  -0.00030 1525 ALA A CA  
943  C  C   . ALA A 66  ? 0.16940 0.14130 0.22150 -0.03340 0.02060  -0.00480 1525 ALA A C   
944  O  O   . ALA A 66  ? 0.19230 0.14910 0.20570 -0.02870 0.01900  -0.00690 1525 ALA A O   
945  C  CB  . ALA A 66  ? 0.19500 0.14560 0.23470 -0.03700 0.00930  0.00330  1525 ALA A CB  
951  N  N   . GLY A 67  ? 0.15470 0.13530 0.21900 -0.03200 0.01780  -0.00580 1526 GLY A N   
952  C  CA  . GLY A 67  ? 0.14600 0.13270 0.20520 -0.02420 0.03020  -0.00400 1526 GLY A CA  
953  C  C   . GLY A 67  ? 0.15060 0.13280 0.19790 -0.02390 0.01270  0.00630  1526 GLY A C   
954  O  O   . GLY A 67  ? 0.16660 0.13780 0.21300 -0.03130 0.01540  0.00750  1526 GLY A O   
958  N  N   . ALA A 68  ? 0.16300 0.13280 0.19410 -0.02720 0.01950  0.00640  1527 ALA A N   
959  C  CA  . ALA A 68  ? 0.16050 0.13200 0.17780 -0.03150 0.02120  0.01080  1527 ALA A CA  
960  C  C   . ALA A 68  ? 0.14660 0.12880 0.19690 -0.03130 0.02390  0.01340  1527 ALA A C   
961  O  O   . ALA A 68  ? 0.15030 0.13130 0.21630 -0.02080 0.02200  0.01870  1527 ALA A O   
962  C  CB  . ALA A 68  ? 0.16950 0.13590 0.17400 -0.03230 0.02690  -0.01040 1527 ALA A CB  
968  N  N   . ARG A 69  ? 0.13930 0.12510 0.20540 -0.02380 0.02650  0.00240  1528 ARG A N   
969  C  CA  . ARG A 69  ? 0.14780 0.12760 0.21490 -0.01320 0.02550  -0.01200 1528 ARG A CA  
970  C  C   . ARG A 69  ? 0.15270 0.12760 0.22210 -0.01100 0.02840  -0.02340 1528 ARG A C   
971  O  O   . ARG A 69  ? 0.15880 0.13720 0.22600 -0.02070 0.03930  -0.03130 1528 ARG A O   
972  C  CB  . ARG A 69  ? 0.15220 0.13720 0.22890 -0.01180 0.01170  -0.02120 1528 ARG A CB  
973  C  CG  . ARG A 69  ? 0.15650 0.14520 0.22120 -0.01320 0.00570  -0.02090 1528 ARG A CG  
974  C  CD  . ARG A 69  ? 0.16630 0.15280 0.24130 -0.02380 0.01450  -0.02650 1528 ARG A CD  
975  N  NE  . ARG A 69  ? 0.16940 0.15570 0.23580 -0.03420 0.02160  -0.03530 1528 ARG A NE  
976  C  CZ  . ARG A 69  ? 0.17290 0.16740 0.24750 -0.04580 0.02750  -0.03890 1528 ARG A CZ  
977  N  NH1 . ARG A 69  ? 0.18850 0.17260 0.27200 -0.04470 0.02290  -0.03890 1528 ARG A NH1 
978  N  NH2 . ARG A 69  ? 0.19070 0.17710 0.26070 -0.04630 0.02860  -0.03270 1528 ARG A NH2 
992  N  N   . CYS A 70  ? 0.14220 0.11820 0.22540 -0.01340 0.01590  -0.02980 1529 CYS A N   
993  C  CA  . CYS A 70  ? 0.14400 0.11700 0.21350 -0.02640 0.02390  -0.01130 1529 CYS A CA  
994  C  C   . CYS A 70  ? 0.13290 0.11280 0.18560 -0.02330 0.03390  -0.01800 1529 CYS A C   
995  O  O   . CYS A 70  ? 0.14320 0.10910 0.18720 -0.01580 0.02550  -0.00810 1529 CYS A O   
996  C  CB  . CYS A 70  ? 0.14090 0.11500 0.20580 -0.03020 0.01450  -0.00880 1529 CYS A CB  
997  S  SG  . CYS A 70  ? 0.14970 0.11740 0.22640 -0.01650 -0.00460 -0.01340 1529 CYS A SG  
1003 N  N   . ASP A 71  ? 0.14520 0.11310 0.18760 -0.02060 0.03770  -0.02120 1530 ASP A N   
1004 C  CA  . ASP A 71  ? 0.15180 0.10940 0.18060 -0.01970 0.02800  -0.00980 1530 ASP A CA  
1005 C  C   . ASP A 71  ? 0.14460 0.11090 0.14670 -0.02320 0.01980  -0.00280 1530 ASP A C   
1006 O  O   . ASP A 71  ? 0.14080 0.11520 0.16430 -0.01820 0.02600  -0.00560 1530 ASP A O   
1007 C  CB  . ASP A 71  ? 0.15340 0.10420 0.19280 -0.02250 0.03190  -0.00690 1530 ASP A CB  
1008 C  CG  . ASP A 71  ? 0.15150 0.10810 0.20080 -0.01360 0.02250  -0.00060 1530 ASP A CG  
1009 O  OD1 . ASP A 71  ? 0.15860 0.11150 0.22290 -0.00790 0.03960  -0.00300 1530 ASP A OD1 
1010 O  OD2 . ASP A 71  ? 0.15140 0.11170 0.20350 -0.01120 0.02290  0.00170  1530 ASP A OD2 
1015 N  N   . PHE A 72  ? 0.13900 0.11540 0.13730 -0.01210 0.00750  -0.01560 1531 PHE A N   
1016 C  CA  . PHE A 72  ? 0.13760 0.11190 0.14530 -0.01630 -0.00260 -0.00590 1531 PHE A CA  
1017 C  C   . PHE A 72  ? 0.13340 0.11140 0.15980 -0.01570 0.00500  -0.00540 1531 PHE A C   
1018 O  O   . PHE A 72  ? 0.13630 0.11760 0.16680 -0.01050 -0.00100 -0.00150 1531 PHE A O   
1019 C  CB  . PHE A 72  ? 0.13280 0.11490 0.15390 -0.01070 0.00670  -0.00160 1531 PHE A CB  
1020 C  CG  . PHE A 72  ? 0.13890 0.12150 0.14590 -0.01300 0.01930  0.00320  1531 PHE A CG  
1021 C  CD1 . PHE A 72  ? 0.14670 0.12750 0.15060 -0.01420 0.01240  0.00660  1531 PHE A CD1 
1022 C  CD2 . PHE A 72  ? 0.14230 0.12860 0.16050 -0.01900 0.01020  0.00210  1531 PHE A CD2 
1023 C  CE1 . PHE A 72  ? 0.15440 0.13760 0.14990 -0.01490 0.01600  0.00970  1531 PHE A CE1 
1024 C  CE2 . PHE A 72  ? 0.14700 0.13470 0.14450 -0.01870 0.01760  0.00640  1531 PHE A CE2 
1025 C  CZ  . PHE A 72  ? 0.15450 0.13830 0.14260 -0.01720 0.02660  0.01800  1531 PHE A CZ  
1035 N  N   . ALA A 73  ? 0.14180 0.10710 0.15610 -0.01140 0.00030  -0.00890 1532 ALA A N   
1036 C  CA  . ALA A 73  ? 0.13430 0.11090 0.14820 -0.00710 -0.01480 -0.00190 1532 ALA A CA  
1037 C  C   . ALA A 73  ? 0.13250 0.11830 0.13660 -0.00700 0.00170  0.00270  1532 ALA A C   
1038 O  O   . ALA A 73  ? 0.13290 0.12730 0.14360 0.00430  0.00310  0.00950  1532 ALA A O   
1039 C  CB  . ALA A 73  ? 0.13620 0.11300 0.16940 -0.01370 -0.01000 -0.00400 1532 ALA A CB  
1045 N  N   . LEU A 74  ? 0.13390 0.12030 0.14070 -0.00540 -0.00680 -0.00310 1533 LEU A N   
1046 C  CA  . LEU A 74  ? 0.14970 0.12440 0.13980 -0.01500 0.01350  0.00070  1533 LEU A CA  
1047 C  C   . LEU A 74  ? 0.12870 0.11750 0.12740 -0.01340 -0.01550 0.00720  1533 LEU A C   
1048 O  O   . LEU A 74  ? 0.14450 0.11890 0.14780 -0.00410 -0.03100 -0.00230 1533 LEU A O   
1049 C  CB  . LEU A 74  ? 0.17570 0.12930 0.15890 -0.01750 0.01810  0.01030  1533 LEU A CB  
1050 C  CG  . LEU A 74  ? 0.20960 0.13330 0.17960 -0.03080 0.01740  0.01430  1533 LEU A CG  
1051 C  CD1 . LEU A 74  ? 0.25650 0.14470 0.20520 -0.03700 0.01100  0.02000  1533 LEU A CD1 
1052 C  CD2 . LEU A 74  ? 0.18370 0.13080 0.19800 -0.03240 0.02020  0.01220  1533 LEU A CD2 
1064 N  N   . PHE A 75  ? 0.12760 0.11790 0.14460 -0.01400 -0.00970 0.01350  1534 PHE A N   
1065 C  CA  . PHE A 75  ? 0.13170 0.11900 0.12260 -0.00920 -0.00850 0.01730  1534 PHE A CA  
1066 C  C   . PHE A 75  ? 0.13470 0.12570 0.12170 -0.01020 -0.01890 0.00990  1534 PHE A C   
1067 O  O   . PHE A 75  ? 0.15060 0.13780 0.13950 -0.01960 -0.01090 0.00900  1534 PHE A O   
1068 C  CB  . PHE A 75  ? 0.14550 0.11750 0.12110 -0.00000 -0.00480 0.01700  1534 PHE A CB  
1069 C  CG  . PHE A 75  ? 0.15270 0.11620 0.10890 0.00270  0.00470  0.01530  1534 PHE A CG  
1070 C  CD1 . PHE A 75  ? 0.15750 0.11460 0.11410 -0.01330 -0.00010 0.02510  1534 PHE A CD1 
1071 C  CD2 . PHE A 75  ? 0.16240 0.12170 0.12620 0.00170  0.00380  0.02520  1534 PHE A CD2 
1072 C  CE1 . PHE A 75  ? 0.16690 0.12040 0.12330 -0.01270 0.00210  0.02880  1534 PHE A CE1 
1073 C  CE2 . PHE A 75  ? 0.18180 0.12790 0.12620 0.00190  0.01500  0.02610  1534 PHE A CE2 
1074 C  CZ  . PHE A 75  ? 0.17410 0.12460 0.11980 -0.00050 0.02470  0.03200  1534 PHE A CZ  
1084 N  N   . LEU A 76  ? 0.13600 0.12550 0.12810 -0.00850 -0.01090 0.00570  1535 LEU A N   
1085 C  CA  . LEU A 76  ? 0.15300 0.12230 0.11420 -0.01350 0.00150  0.02590  1535 LEU A CA  
1086 C  C   . LEU A 76  ? 0.13550 0.12320 0.11600 -0.01310 0.01310  0.02750  1535 LEU A C   
1087 O  O   . LEU A 76  ? 0.14550 0.12820 0.13990 -0.00190 0.01950  0.03870  1535 LEU A O   
1088 C  CB  . LEU A 76  ? 0.17840 0.12480 0.10630 -0.01460 -0.00910 0.03540  1535 LEU A CB  
1089 C  CG  . LEU A 76  ? 0.18880 0.13370 0.13110 -0.01680 -0.01860 0.02880  1535 LEU A CG  
1090 C  CD1 . LEU A 76  ? 0.18340 0.13770 0.13510 -0.01070 -0.04490 0.02230  1535 LEU A CD1 
1091 C  CD2 . LEU A 76  ? 0.20600 0.13850 0.15130 -0.02440 -0.01720 0.02590  1535 LEU A CD2 
1103 N  N   . GLY A 77  ? 0.14440 0.12290 0.12660 -0.01730 0.00700  0.00950  1536 GLY A N   
1104 C  CA  . GLY A 77  ? 0.14810 0.12750 0.13360 -0.01170 0.01920  0.00960  1536 GLY A CA  
1105 C  C   . GLY A 77  ? 0.15770 0.13250 0.11550 -0.00370 0.01770  0.00930  1536 GLY A C   
1106 O  O   . GLY A 77  ? 0.17690 0.14180 0.12940 -0.01190 0.00610  -0.00430 1536 GLY A O   
1110 N  N   . ALA A 78  ? 0.14530 0.13410 0.09860 -0.00390 0.01690  0.01260  1537 ALA A N   
1111 C  CA  . ALA A 78  ? 0.15330 0.15150 0.11170 -0.00750 0.02830  0.00430  1537 ALA A CA  
1112 C  C   . ALA A 78  ? 0.16130 0.17180 0.10940 -0.00370 0.01680  0.01050  1537 ALA A C   
1113 O  O   . ALA A 78  ? 0.17350 0.17330 0.13240 0.00120  0.01560  0.01610  1537 ALA A O   
1114 C  CB  . ALA A 78  ? 0.14670 0.15290 0.12390 -0.01460 0.01970  -0.00740 1537 ALA A CB  
1120 N  N   . ALA A 79  ? 0.18080 0.21070 0.12500 -0.00530 0.01440  0.00250  1538 ALA A N   
1121 C  CA  . ALA A 79  ? 0.23670 0.25330 0.18600 -0.01310 0.03610  0.01730  1538 ALA A CA  
1122 C  C   . ALA A 79  ? 0.19490 0.22920 0.14610 -0.00780 0.04450  0.00130  1538 ALA A C   
1123 O  O   . ALA A 79  ? 0.17410 0.19580 0.15010 0.00140  0.03710  0.01630  1538 ALA A O   
1124 C  CB  . ALA A 79  ? 0.31360 0.30730 0.31470 -0.04050 0.06190  -0.01280 1538 ALA A CB  
1130 N  N   . SER A 80  ? 0.20270 0.22390 0.15720 -0.00900 0.04770  -0.01120 1539 SER A N   
1131 C  CA  . SER A 80  ? 0.23160 0.23010 0.18190 0.00550  0.04700  -0.01620 1539 SER A CA  
1132 C  C   . SER A 80  ? 0.26600 0.23680 0.18770 -0.00360 0.02990  -0.01140 1539 SER A C   
1133 O  O   . SER A 80  ? 0.29380 0.24150 0.20250 -0.01190 0.02110  -0.01420 1539 SER A O   
1134 C  CB  . SER A 80  ? 0.23990 0.24060 0.22220 0.00680  0.06270  -0.01620 1539 SER A CB  
1135 O  OG  . SER A 80  ? 0.24530 0.25320 0.26150 0.00670  0.08490  -0.00930 1539 SER A OG  
1141 N  N   . GLU A 81  ? 0.27010 0.24360 0.19410 0.00160  0.02010  0.00770  1540 GLU A N   
1142 C  CA  A GLU A 81  ? 0.27720 0.25110 0.20660 0.00140  0.01660  0.01740  1540 GLU A CA  
1143 C  CA  B GLU A 81  ? 0.27350 0.24810 0.19590 -0.00070 0.01860  0.01810  1540 GLU A CA  
1144 C  C   . GLU A 81  ? 0.27430 0.24210 0.17610 -0.00080 0.01340  0.02240  1540 GLU A C   
1145 O  O   . GLU A 81  ? 0.30730 0.25260 0.20310 0.01420  -0.00470 0.02920  1540 GLU A O   
1146 C  CB  A GLU A 81  ? 0.29350 0.26650 0.25490 0.00040  0.01640  0.01900  1540 GLU A CB  
1147 C  CB  B GLU A 81  ? 0.28160 0.25750 0.22240 -0.00480 0.02340  0.02110  1540 GLU A CB  
1148 C  CG  A GLU A 81  ? 0.31290 0.28000 0.31020 -0.00280 0.01460  0.01660  1540 GLU A CG  
1149 C  CG  B GLU A 81  ? 0.29620 0.26570 0.25270 -0.01040 0.02810  0.01970  1540 GLU A CG  
1150 C  CD  A GLU A 81  ? 0.33700 0.29330 0.35620 -0.00540 0.01790  0.01040  1540 GLU A CD  
1151 C  CD  B GLU A 81  ? 0.31800 0.27380 0.28490 -0.01360 0.02700  0.01310  1540 GLU A CD  
1152 O  OE1 A GLU A 81  ? 0.34180 0.29690 0.37260 -0.01400 0.01660  0.00810  1540 GLU A OE1 
1153 O  OE1 B GLU A 81  ? 0.32280 0.27750 0.29290 -0.01050 0.02360  0.00620  1540 GLU A OE1 
1154 O  OE2 A GLU A 81  ? 0.35900 0.30050 0.37680 -0.00200 0.01350  0.01140  1540 GLU A OE2 
1155 O  OE2 B GLU A 81  ? 0.33170 0.27730 0.30060 -0.02110 0.03300  0.01590  1540 GLU A OE2 
1168 N  N   . ASN A 82  ? 0.24430 0.21920 0.13720 -0.02310 0.02380  0.02110  1541 ASN A N   
1169 C  CA  . ASN A 82  ? 0.22720 0.19670 0.13350 -0.02590 0.00740  0.01540  1541 ASN A CA  
1170 C  C   . ASN A 82  ? 0.22110 0.18370 0.13440 -0.01630 0.00430  0.00680  1541 ASN A C   
1171 O  O   . ASN A 82  ? 0.23550 0.18030 0.15650 -0.00990 -0.00320 0.00850  1541 ASN A O   
1172 C  CB  . ASN A 82  ? 0.21130 0.18650 0.14150 -0.03600 -0.00090 0.01590  1541 ASN A CB  
1173 C  CG  . ASN A 82  ? 0.19950 0.17530 0.13050 -0.03570 -0.00560 0.01830  1541 ASN A CG  
1174 O  OD1 . ASN A 82  ? 0.20330 0.16680 0.13710 -0.02860 -0.00080 0.00460  1541 ASN A OD1 
1175 N  ND2 . ASN A 82  ? 0.19610 0.17140 0.12570 -0.04410 -0.00710 0.02630  1541 ASN A ND2 
1182 N  N   . ALA A 83  ? 0.21560 0.17990 0.14130 -0.00670 -0.00550 -0.00580 1542 ALA A N   
1183 C  CA  . ALA A 83  ? 0.22840 0.17640 0.13820 -0.00550 -0.01730 -0.00490 1542 ALA A CA  
1184 C  C   . ALA A 83  ? 0.24950 0.18480 0.12920 -0.01000 -0.01980 0.00100  1542 ALA A C   
1185 O  O   . ALA A 83  ? 0.27610 0.19140 0.14570 -0.01070 -0.01120 0.00200  1542 ALA A O   
1186 C  CB  . ALA A 83  ? 0.23750 0.17500 0.16590 0.00050  -0.01950 -0.01650 1542 ALA A CB  
1192 N  N   . GLY A 84  ? 0.25320 0.19230 0.16110 -0.00460 -0.03760 0.01780  1543 GLY A N   
1193 C  CA  . GLY A 84  ? 0.26730 0.20310 0.19720 -0.00620 -0.03820 0.03400  1543 GLY A CA  
1194 C  C   . GLY A 84  ? 0.26800 0.21260 0.19780 -0.00450 -0.03400 0.04660  1543 GLY A C   
1195 O  O   . GLY A 84  ? 0.28140 0.22430 0.22570 -0.01620 -0.06040 0.06380  1543 GLY A O   
1199 N  N   . THR A 85  ? 0.25380 0.20890 0.15790 -0.00250 -0.01220 0.03410  1544 THR A N   
1200 C  CA  . THR A 85  ? 0.26610 0.20770 0.15550 -0.00550 0.00250  0.03720  1544 THR A CA  
1201 C  C   . THR A 85  ? 0.27060 0.20430 0.15710 -0.00760 -0.00230 0.03910  1544 THR A C   
1202 O  O   . THR A 85  ? 0.30520 0.20530 0.19290 -0.00300 -0.00040 0.03940  1544 THR A O   
1203 C  CB  . THR A 85  ? 0.27350 0.20750 0.16320 -0.00590 0.01870  0.03690  1544 THR A CB  
1204 O  OG1 . THR A 85  ? 0.24400 0.20050 0.16890 -0.01300 0.01670  0.03760  1544 THR A OG1 
1205 C  CG2 . THR A 85  ? 0.29800 0.21290 0.17170 -0.00750 0.02440  0.03520  1544 THR A CG2 
1213 N  N   . LEU A 86  ? 0.23750 0.20300 0.14370 -0.01200 -0.00000 0.03290  1545 LEU A N   
1214 C  CA  . LEU A 86  ? 0.22570 0.20630 0.13190 -0.00390 -0.00170 0.01580  1545 LEU A CA  
1215 C  C   . LEU A 86  ? 0.22930 0.21180 0.15330 0.00560  -0.00890 0.01030  1545 LEU A C   
1216 O  O   . LEU A 86  ? 0.23650 0.20910 0.15020 0.01770  0.00460  0.00820  1545 LEU A O   
1217 C  CB  . LEU A 86  ? 0.22090 0.20500 0.12220 0.00030  0.00150  0.01170  1545 LEU A CB  
1218 C  CG  . LEU A 86  ? 0.22400 0.20500 0.13460 0.00550  0.00340  0.00590  1545 LEU A CG  
1219 C  CD1 . LEU A 86  ? 0.23060 0.20650 0.14640 0.01160  0.00010  0.00610  1545 LEU A CD1 
1220 C  CD2 . LEU A 86  ? 0.22670 0.20620 0.16040 0.00020  0.00370  0.00410  1545 LEU A CD2 
1232 N  N   . GLY A 87  ? 0.23250 0.22250 0.18500 0.00560  -0.02350 0.00620  1546 GLY A N   
1233 C  CA  . GLY A 87  ? 0.24540 0.23610 0.21020 0.01230  -0.02980 0.00550  1546 GLY A CA  
1234 C  C   . GLY A 87  ? 0.25760 0.24640 0.21430 0.03240  -0.03060 0.00830  1546 GLY A C   
1235 O  O   . GLY A 87  ? 0.27810 0.25330 0.23070 0.03690  -0.02390 0.01070  1546 GLY A O   
1239 N  N   . THR A 88  ? 0.27080 0.24690 0.22960 0.03950  -0.04080 0.00750  1547 THR A N   
1240 C  CA  . THR A 88  ? 0.30270 0.24760 0.26170 0.03390  -0.03770 0.01500  1547 THR A CA  
1241 C  C   . THR A 88  ? 0.28580 0.22760 0.24250 0.03430  -0.02660 0.00700  1547 THR A C   
1242 O  O   . THR A 88  ? 0.30040 0.23110 0.28690 0.04960  -0.03300 -0.00930 1547 THR A O   
1243 C  CB  . THR A 88  ? 0.35390 0.26710 0.32130 0.03280  -0.02650 0.02440  1547 THR A CB  
1244 O  OG1 . THR A 88  ? 0.39490 0.27790 0.37170 0.02470  0.00140  0.03300  1547 THR A OG1 
1245 C  CG2 . THR A 88  ? 0.36570 0.27440 0.32920 0.03650  -0.03650 0.02920  1547 THR A CG2 
1253 N  N   . VAL A 89  ? 0.25080 0.20610 0.18380 0.01310  0.00140  0.02630  1548 VAL A N   
1254 C  CA  . VAL A 89  ? 0.22510 0.19390 0.19120 -0.00750 0.01050  0.02950  1548 VAL A CA  
1255 C  C   . VAL A 89  ? 0.18020 0.16930 0.18220 -0.00010 -0.00710 0.03170  1548 VAL A C   
1256 O  O   . VAL A 89  ? 0.17540 0.15920 0.20340 0.00300  -0.00220 0.02520  1548 VAL A O   
1257 C  CB  . VAL A 89  ? 0.23540 0.20470 0.20890 -0.02300 0.01150  0.03250  1548 VAL A CB  
1258 C  CG1 . VAL A 89  ? 0.25720 0.20550 0.21800 -0.03140 0.02600  0.04350  1548 VAL A CG1 
1259 C  CG2 . VAL A 89  ? 0.20530 0.21130 0.20510 -0.01960 -0.00100 0.02100  1548 VAL A CG2 
1269 N  N   . ALA A 90  ? 0.15860 0.16190 0.17730 -0.00760 -0.01350 0.02930  1549 ALA A N   
1270 C  CA  . ALA A 90  ? 0.16040 0.16140 0.17000 -0.01200 -0.01090 0.01510  1549 ALA A CA  
1271 C  C   . ALA A 90  ? 0.16680 0.15780 0.15460 -0.01810 -0.02310 0.01780  1549 ALA A C   
1272 O  O   . ALA A 90  ? 0.17270 0.15710 0.16000 -0.02250 -0.03180 0.01860  1549 ALA A O   
1273 C  CB  . ALA A 90  ? 0.15840 0.16310 0.17160 -0.02450 -0.00320 0.00680  1549 ALA A CB  
1279 N  N   . GLY A 91  ? 0.16690 0.15760 0.16760 -0.00990 -0.01320 0.02020  1550 GLY A N   
1280 C  CA  . GLY A 91  ? 0.16020 0.16200 0.16300 -0.00070 -0.01600 0.01430  1550 GLY A CA  
1281 C  C   . GLY A 91  ? 0.16250 0.15910 0.15920 0.00150  0.00190  0.01880  1550 GLY A C   
1282 O  O   . GLY A 91  ? 0.17720 0.16980 0.16850 -0.01270 0.00740  0.03060  1550 GLY A O   
1286 N  N   . SER A 92  ? 0.15720 0.14760 0.16950 0.00220  -0.00030 0.02270  1551 SER A N   
1287 C  CA  A SER A 92  ? 0.16400 0.14450 0.17540 -0.00650 0.00110  0.02790  1551 SER A CA  
1288 C  CA  B SER A 92  ? 0.16380 0.14540 0.16540 -0.00580 0.00350  0.02740  1551 SER A CA  
1289 C  C   . SER A 92  ? 0.15490 0.14420 0.17190 -0.00300 -0.00950 0.02010  1551 SER A C   
1290 O  O   . SER A 92  ? 0.15820 0.14570 0.17630 -0.00090 -0.02230 0.01860  1551 SER A O   
1291 C  CB  A SER A 92  ? 0.18970 0.14280 0.19330 -0.01210 0.00100  0.02380  1551 SER A CB  
1292 C  CB  B SER A 92  ? 0.18420 0.14360 0.16360 -0.01280 0.00800  0.03090  1551 SER A CB  
1293 O  OG  A SER A 92  ? 0.20010 0.14540 0.20810 -0.00940 -0.01350 0.01710  1551 SER A OG  
1294 O  OG  B SER A 92  ? 0.19010 0.14350 0.16770 -0.01410 -0.00390 0.03360  1551 SER A OG  
1305 N  N   . ALA A 93  ? 0.15370 0.14160 0.16360 -0.00440 -0.01330 0.01810  1552 ALA A N   
1306 C  CA  . ALA A 93  ? 0.15070 0.13790 0.15730 0.00400  -0.00440 0.01150  1552 ALA A CA  
1307 C  C   . ALA A 93  ? 0.14220 0.12680 0.17000 0.00500  0.00110  -0.00260 1552 ALA A C   
1308 O  O   . ALA A 93  ? 0.13610 0.12910 0.20190 0.01430  -0.00370 -0.00970 1552 ALA A O   
1309 C  CB  . ALA A 93  ? 0.15710 0.14320 0.16880 0.00210  -0.00870 0.01700  1552 ALA A CB  
1315 N  N   . ALA A 94  ? 0.13710 0.12090 0.15930 0.00250  0.00190  0.00160  1553 ALA A N   
1316 C  CA  . ALA A 94  ? 0.13850 0.11680 0.14570 0.00110  -0.00350 -0.00010 1553 ALA A CA  
1317 C  C   . ALA A 94  ? 0.13060 0.11420 0.13900 -0.00160 0.00740  -0.00410 1553 ALA A C   
1318 O  O   . ALA A 94  ? 0.14440 0.12080 0.16290 -0.00480 0.01690  -0.00390 1553 ALA A O   
1319 C  CB  . ALA A 94  ? 0.15330 0.11710 0.14800 0.00950  0.00790  0.00030  1553 ALA A CB  
1325 N  N   . GLY A 95  ? 0.13460 0.10660 0.14730 0.00430  0.00070  -0.00010 1554 GLY A N   
1326 C  CA  . GLY A 95  ? 0.13250 0.10900 0.15750 0.00510  0.00520  -0.00330 1554 GLY A CA  
1327 C  C   . GLY A 95  ? 0.12960 0.11160 0.14070 -0.00530 -0.00400 -0.00040 1554 GLY A C   
1328 O  O   . GLY A 95  ? 0.12540 0.11120 0.15740 -0.01170 0.00230  -0.01120 1554 GLY A O   
1332 N  N   . LEU A 96  ? 0.12850 0.11470 0.13740 -0.01110 -0.00790 0.00820  1555 LEU A N   
1333 C  CA  . LEU A 96  ? 0.14050 0.11950 0.11590 -0.00520 -0.01380 0.00710  1555 LEU A CA  
1334 C  C   . LEU A 96  ? 0.12430 0.11170 0.12020 -0.00220 -0.00680 0.01480  1555 LEU A C   
1335 O  O   . LEU A 96  ? 0.13060 0.11630 0.14070 0.00470  -0.00230 0.02480  1555 LEU A O   
1336 C  CB  . LEU A 96  ? 0.15060 0.13670 0.09980 -0.00670 -0.00280 -0.00280 1555 LEU A CB  
1337 C  CG  . LEU A 96  ? 0.14920 0.14910 0.10580 -0.00450 0.00170  -0.01020 1555 LEU A CG  
1338 C  CD1 . LEU A 96  ? 0.15780 0.14960 0.12050 -0.01540 0.00970  0.00110  1555 LEU A CD1 
1339 C  CD2 . LEU A 96  ? 0.16470 0.16280 0.13570 0.00210  -0.02400 -0.02150 1555 LEU A CD2 
1351 N  N   . KCX A 97  ? 0.12020 0.11710 0.13140 -0.00340 -0.00510 0.02480  1556 KCX A N   
1352 C  CA  . KCX A 97  ? 0.12260 0.12340 0.10880 -0.00700 -0.00730 0.01610  1556 KCX A CA  
1353 C  CB  . KCX A 97  ? 0.13290 0.12340 0.10210 -0.01680 -0.01420 0.01090  1556 KCX A CB  
1354 C  CG  . KCX A 97  ? 0.13890 0.12810 0.11980 -0.01230 -0.02590 0.00810  1556 KCX A CG  
1355 C  CD  . KCX A 97  ? 0.13560 0.13050 0.12950 -0.01310 -0.02870 0.00140  1556 KCX A CD  
1356 C  CE  . KCX A 97  ? 0.14660 0.13060 0.13950 -0.01030 -0.03860 0.00420  1556 KCX A CE  
1357 N  NZ  . KCX A 97  ? 0.15000 0.12240 0.14780 -0.01870 -0.03270 0.01800  1556 KCX A NZ  
1358 C  C   . KCX A 97  ? 0.12040 0.12820 0.08720 0.00170  0.00540  0.01860  1556 KCX A C   
1359 O  O   . KCX A 97  ? 0.13410 0.13720 0.12160 -0.00120 0.01070  0.01540  1556 KCX A O   
1360 C  CX  . KCX A 97  ? 0.12580 0.12700 0.14430 -0.01800 -0.01490 0.01700  1556 KCX A CX  
1361 O  OQ1 . KCX A 97  ? 0.12120 0.12410 0.14280 -0.00850 -0.01600 0.00710  1556 KCX A OQ1 
1362 O  OQ2 . KCX A 97  ? 0.11820 0.13610 0.17540 -0.02100 0.00280  0.01920  1556 KCX A OQ2 
1374 N  N   A LEU A 98  ? 0.12470 0.13390 0.10810 0.00010  0.01570  -0.00080 1557 LEU A N   
1375 N  N   B LEU A 98  ? 0.12470 0.13390 0.10810 0.00010  0.01570  -0.00080 1557 LEU A N   
1376 C  CA  A LEU A 98  ? 0.13520 0.13960 0.12200 0.00570  0.00770  -0.01250 1557 LEU A CA  
1377 C  CA  B LEU A 98  ? 0.13520 0.13960 0.12200 0.00570  0.00770  -0.01250 1557 LEU A CA  
1378 C  C   A LEU A 98  ? 0.15280 0.14130 0.10480 0.00350  0.01140  -0.00780 1557 LEU A C   
1379 C  C   B LEU A 98  ? 0.15280 0.14130 0.10480 0.00350  0.01140  -0.00780 1557 LEU A C   
1380 O  O   A LEU A 98  ? 0.15560 0.14950 0.11420 0.01500  0.01280  0.00400  1557 LEU A O   
1381 O  O   B LEU A 98  ? 0.15560 0.14950 0.11420 0.01500  0.01280  0.00400  1557 LEU A O   
1382 C  CB  A LEU A 98  ? 0.37885 0.37885 0.37885 0.00000  0.00000  -0.00000 1557 LEU A CB  
1383 C  CB  B LEU A 98  ? 0.37885 0.37885 0.37885 0.00000  0.00000  -0.00000 1557 LEU A CB  
1384 C  CG  A LEU A 98  ? 0.37885 0.37885 0.37885 0.00000  0.00000  0.00000  1557 LEU A CG  
1385 C  CG  B LEU A 98  ? 0.37885 0.37885 0.37885 0.00000  -0.00000 -0.00000 1557 LEU A CG  
1386 C  CD1 A LEU A 98  ? 0.37885 0.37885 0.37885 -0.00000 -0.00000 -0.00000 1557 LEU A CD1 
1387 C  CD1 B LEU A 98  ? 0.37885 0.37885 0.37885 -0.00000 -0.00000 0.00000  1557 LEU A CD1 
1388 C  CD2 A LEU A 98  ? 0.37885 0.37885 0.37885 -0.00000 -0.00000 -0.00000 1557 LEU A CD2 
1389 C  CD2 B LEU A 98  ? 0.37885 0.37885 0.37885 -0.00000 -0.00000 -0.00000 1557 LEU A CD2 
1412 N  N   A TYR A 99  ? 0.15650 0.14080 0.10770 -0.00460 0.00570  0.00660  1558 TYR A N   
1413 N  N   B TYR A 99  ? 0.15650 0.14070 0.10770 -0.00460 0.00580  0.00660  1558 TYR A N   
1414 C  CA  A TYR A 99  ? 0.16060 0.14800 0.13150 -0.00530 -0.01020 0.00820  1558 TYR A CA  
1415 C  CA  B TYR A 99  ? 0.16050 0.14800 0.13150 -0.00530 -0.01020 0.00810  1558 TYR A CA  
1416 C  C   A TYR A 99  ? 0.16450 0.14690 0.11280 -0.00690 -0.00470 0.00410  1558 TYR A C   
1417 C  C   B TYR A 99  ? 0.16450 0.14690 0.11280 -0.00690 -0.00470 0.00410  1558 TYR A C   
1418 O  O   A TYR A 99  ? 0.17920 0.14980 0.14410 -0.00850 0.01680  0.01070  1558 TYR A O   
1419 O  O   B TYR A 99  ? 0.17920 0.14980 0.14420 -0.00840 0.01680  0.01070  1558 TYR A O   
1420 C  CB  A TYR A 99  ? 0.16140 0.15600 0.15360 -0.00510 -0.01630 0.01270  1558 TYR A CB  
1421 C  CB  B TYR A 99  ? 0.16140 0.15610 0.15360 -0.00510 -0.01630 0.01270  1558 TYR A CB  
1422 C  CG  A TYR A 99  ? 0.16550 0.16330 0.16200 -0.00130 -0.00520 0.00990  1558 TYR A CG  
1423 C  CG  B TYR A 99  ? 0.16560 0.16350 0.16210 -0.00120 -0.00520 0.00970  1558 TYR A CG  
1424 C  CD1 A TYR A 99  ? 0.13810 0.16750 0.17610 0.00210  -0.01580 0.00210  1558 TYR A CD1 
1425 C  CD1 B TYR A 99  ? 0.13800 0.16740 0.17620 0.00210  -0.01580 0.00220  1558 TYR A CD1 
1426 C  CD2 A TYR A 99  ? 0.16620 0.16330 0.15470 -0.00850 0.00230  0.01330  1558 TYR A CD2 
1427 C  CD2 B TYR A 99  ? 0.16630 0.16330 0.15470 -0.00850 0.00230  0.01340  1558 TYR A CD2 
1428 C  CE1 A TYR A 99  ? 0.13930 0.16700 0.16640 -0.00280 -0.00480 0.00080  1558 TYR A CE1 
1429 C  CE1 B TYR A 99  ? 0.13930 0.16710 0.16640 -0.00290 -0.00480 0.00070  1558 TYR A CE1 
1430 C  CE2 A TYR A 99  ? 0.15840 0.16390 0.14550 -0.01260 -0.00390 0.00730  1558 TYR A CE2 
1431 C  CE2 B TYR A 99  ? 0.15840 0.16400 0.14540 -0.01260 -0.00390 0.00720  1558 TYR A CE2 
1432 C  CZ  A TYR A 99  ? 0.13590 0.16110 0.14580 -0.01240 -0.00890 0.00580  1558 TYR A CZ  
1433 C  CZ  B TYR A 99  ? 0.13600 0.16120 0.14580 -0.01240 -0.00880 0.00590  1558 TYR A CZ  
1434 O  OH  A TYR A 99  ? 0.11160 0.15470 0.13620 -0.01900 -0.02220 -0.00070 1558 TYR A OH  
1435 O  OH  B TYR A 99  ? 0.11090 0.15390 0.13610 -0.01920 -0.02220 -0.00100 1558 TYR A OH  
1453 N  N   . LEU A 100 ? 0.15290 0.14450 0.10810 -0.00060 -0.00670 -0.00300 1559 LEU A N   
1454 C  CA  . LEU A 100 ? 0.15740 0.15400 0.14630 -0.00030 0.01570  -0.01210 1559 LEU A CA  
1455 C  C   . LEU A 100 ? 0.16240 0.17120 0.19710 0.00720  0.02450  -0.01640 1559 LEU A C   
1456 O  O   . LEU A 100 ? 0.17860 0.17440 0.25820 0.00950  0.02920  -0.04700 1559 LEU A O   
1457 C  CB  . LEU A 100 ? 0.16060 0.14740 0.13210 -0.00190 0.01500  -0.00580 1559 LEU A CB  
1458 C  CG  . LEU A 100 ? 0.17400 0.15270 0.14630 -0.01330 -0.00420 -0.01040 1559 LEU A CG  
1459 C  CD1 . LEU A 100 ? 0.16570 0.15140 0.15600 -0.00910 -0.00700 -0.01240 1559 LEU A CD1 
1460 C  CD2 . LEU A 100 ? 0.19730 0.15770 0.16900 -0.02110 -0.02230 -0.01310 1559 LEU A CD2 
1472 N  N   . ASN A 101 ? 0.16030 0.20000 0.20300 0.02350  0.00340  0.00460  1560 ASN A N   
1473 C  CA  . ASN A 101 ? 0.16770 0.24100 0.22010 0.01690  0.00980  0.00650  1560 ASN A CA  
1474 C  C   . ASN A 101 ? 0.24270 0.32000 0.29680 -0.00170 0.02310  0.02420  1560 ASN A C   
1475 O  O   . ASN A 101 ? 0.24760 0.32990 0.29670 -0.00340 0.02420  0.03560  1560 ASN A O   
1476 C  CB  . ASN A 101 ? 0.14450 0.21200 0.20510 0.02400  -0.00650 -0.00900 1560 ASN A CB  
1477 C  CG  . ASN A 101 ? 0.15800 0.18650 0.19100 0.02400  0.01200  -0.01500 1560 ASN A CG  
1478 O  OD1 . ASN A 101 ? 0.16460 0.17830 0.17920 0.01830  0.00650  -0.01110 1560 ASN A OD1 
1479 N  ND2 . ASN A 101 ? 0.18250 0.17870 0.22050 0.02020  0.04410  -0.03780 1560 ASN A ND2 
1486 N  N   . GLU A 102 ? 0.30600 0.38190 0.35790 -0.01820 0.03100  0.02010  1561 GLU A N   
1487 C  CA  . GLU A 102 ? 0.38570 0.43870 0.42250 -0.01860 0.03350  0.00360  1561 GLU A CA  
1488 C  C   . GLU A 102 ? 0.45680 0.47630 0.47910 -0.01720 0.02280  -0.00590 1561 GLU A C   
1489 O  O   . GLU A 102 ? 0.47760 0.49110 0.49680 -0.01550 0.02500  -0.01030 1561 GLU A O   
1490 C  CB  . GLU A 102 ? 0.39990 0.44870 0.43280 -0.02430 0.04550  0.00280  1561 GLU A CB  
1493 N  N   . THR A 103 ? 0.38210 0.38710 0.38180 -0.00060 0.00010  -0.00020 1562 THR A N   
1494 C  CA  . THR A 103 ? 0.38080 0.38100 0.38080 0.00010  0.00000  0.00000  1562 THR A CA  
1495 C  C   . THR A 103 ? 0.38090 0.38090 0.38090 0.00000  -0.00000 0.00010  1562 THR A C   
1496 O  O   . THR A 103 ? 0.38090 0.38090 0.38090 0.00010  0.00010  0.00000  1562 THR A O   
1497 C  CB  . THR A 103 ? 0.38070 0.38080 0.38080 -0.00000 0.00000  -0.00000 1562 THR A CB  
1500 N  N   . PHE A 104 ? 0.38090 0.38090 0.38090 0.00010  0.00000  -0.00000 1563 PHE A N   
1501 C  CA  . PHE A 104 ? 0.38080 0.38080 0.38080 -0.00010 0.00000  0.00000  1563 PHE A CA  
1502 C  C   . PHE A 104 ? 0.38090 0.38090 0.38090 -0.00000 0.00010  0.00000  1563 PHE A C   
1503 O  O   . PHE A 104 ? 0.38080 0.38080 0.38090 -0.00010 0.00000  -0.00010 1563 PHE A O   
1504 C  CB  . PHE A 104 ? 0.38090 0.38090 0.38090 0.00000  0.00000  0.00000  1563 PHE A CB  
1507 N  N   . SER A 105 ? 0.38090 0.38090 0.38090 -0.00000 0.00000  -0.00000 1564 SER A N   
1508 C  CA  . SER A 105 ? 0.38080 0.38090 0.38090 -0.00000 0.00000  0.00000  1564 SER A CA  
1509 C  C   . SER A 105 ? 0.38090 0.38090 0.38090 -0.00000 -0.00000 -0.00000 1564 SER A C   
1510 O  O   . SER A 105 ? 0.38090 0.38090 0.38090 -0.00000 -0.00000 -0.00000 1564 SER A O   
1511 C  CB  . SER A 105 ? 0.38090 0.38090 0.38090 0.00000  0.00000  -0.00000 1564 SER A CB  
1514 N  N   . GLU A 106 ? 0.38090 0.38090 0.38090 -0.00000 -0.00000 0.00000  1565 GLU A N   
1515 C  CA  . GLU A 106 ? 0.38090 0.38080 0.38090 0.00000  -0.00000 -0.00000 1565 GLU A CA  
1516 C  C   . GLU A 106 ? 0.38070 0.38110 0.38100 0.00060  -0.00040 -0.00060 1565 GLU A C   
1517 O  O   . GLU A 106 ? 0.38080 0.38080 0.38080 0.00000  -0.00000 -0.00000 1565 GLU A O   
1518 C  CB  . GLU A 106 ? 0.38080 0.38080 0.38080 0.00000  -0.00000 -0.00000 1565 GLU A CB  
1521 N  N   . LEU A 107 ? 0.38070 0.38070 0.38070 -0.00000 -0.00000 -0.00000 1566 LEU A N   
1522 C  CA  . LEU A 107 ? 0.38070 0.38070 0.38070 0.00000  -0.00000 -0.00000 1566 LEU A CA  
1523 C  C   . LEU A 107 ? 0.38050 0.38050 0.38060 -0.00000 0.00000  -0.00000 1566 LEU A C   
1524 O  O   . LEU A 107 ? 0.38070 0.38070 0.38070 0.00000  0.00000  -0.00000 1566 LEU A O   
1525 C  CB  . LEU A 107 ? 0.38070 0.38070 0.38070 0.00000  -0.00000 0.00000  1566 LEU A CB  
1526 C  CG  . LEU A 107 ? 0.38070 0.38070 0.38070 -0.00000 -0.00000 -0.00000 1566 LEU A CG  
1527 C  CD1 . LEU A 107 ? 0.38070 0.38070 0.38070 0.00000  -0.00000 -0.00000 1566 LEU A CD1 
1528 C  CD2 . LEU A 107 ? 0.38070 0.38070 0.38070 0.00000  0.00000  -0.00000 1566 LEU A CD2 
1540 N  N   . ARG A 108 ? 0.24220 0.33870 0.26360 -0.00170 0.02230  -0.01750 1567 ARG A N   
1541 C  CA  . ARG A 108 ? 0.26800 0.34370 0.26830 -0.00560 0.07570  -0.01510 1567 ARG A CA  
1542 C  C   . ARG A 108 ? 0.24250 0.30230 0.22010 -0.02000 0.09020  -0.02010 1567 ARG A C   
1543 O  O   . ARG A 108 ? 0.23470 0.28740 0.22280 -0.03780 0.08010  -0.01770 1567 ARG A O   
1544 C  CB  . ARG A 108 ? 0.33820 0.39120 0.34230 0.00060  0.09060  -0.01330 1567 ARG A CB  
1547 N  N   . LEU A 109 ? 0.24170 0.27840 0.22500 -0.01320 0.07370  -0.02150 1568 LEU A N   
1548 C  CA  . LEU A 109 ? 0.24180 0.26040 0.23460 -0.01030 0.05390  -0.01930 1568 LEU A CA  
1549 C  C   . LEU A 109 ? 0.26030 0.26390 0.30510 -0.00770 0.06070  -0.03280 1568 LEU A C   
1550 O  O   . LEU A 109 ? 0.29430 0.26470 0.35430 0.00210  0.06630  -0.04140 1568 LEU A O   
1551 C  CB  . LEU A 109 ? 0.23200 0.24490 0.19900 -0.00880 0.03820  -0.00860 1568 LEU A CB  
1552 C  CG  . LEU A 109 ? 0.22700 0.23670 0.18170 -0.00480 0.02940  0.00780  1568 LEU A CG  
1553 C  CD1 . LEU A 109 ? 0.23440 0.23430 0.19220 0.00040  0.04190  0.01140  1568 LEU A CD1 
1554 C  CD2 . LEU A 109 ? 0.23380 0.23790 0.19050 -0.01000 0.01320  0.01730  1568 LEU A CD2 
1566 N  N   . ASP A 110 ? 0.25420 0.26830 0.35070 -0.01990 0.04240  -0.03830 1569 ASP A N   
1567 C  CA  . ASP A 110 ? 0.27360 0.27540 0.37480 -0.02520 0.03820  -0.03950 1569 ASP A CA  
1568 C  C   . ASP A 110 ? 0.24180 0.24550 0.35360 -0.01910 0.03140  -0.04770 1569 ASP A C   
1569 O  O   . ASP A 110 ? 0.24780 0.24740 0.37590 -0.01610 0.03790  -0.05750 1569 ASP A O   
1570 C  CB  . ASP A 110 ? 0.32720 0.30840 0.41170 -0.03440 0.04530  -0.02700 1569 ASP A CB  
1571 C  CG  . ASP A 110 ? 0.40180 0.33980 0.46060 -0.03670 0.03040  -0.01460 1569 ASP A CG  
1572 O  OD1 . ASP A 110 ? 0.43270 0.34780 0.48650 -0.03280 0.02530  -0.00950 1569 ASP A OD1 
1573 O  OD2 . ASP A 110 ? 0.43530 0.35960 0.48620 -0.03520 0.02520  -0.00900 1569 ASP A OD2 
1578 N  N   . SER A 111 ? 0.20920 0.21630 0.28530 -0.01290 0.03730  -0.03780 1570 SER A N   
1579 C  CA  . SER A 111 ? 0.20100 0.19360 0.21980 -0.01150 0.02760  -0.02100 1570 SER A CA  
1580 C  C   . SER A 111 ? 0.18580 0.16580 0.16970 -0.00420 0.00820  -0.01510 1570 SER A C   
1581 O  O   . SER A 111 ? 0.20020 0.15320 0.15350 -0.00550 0.00070  -0.01220 1570 SER A O   
1582 C  CB  . SER A 111 ? 0.22050 0.19990 0.19850 -0.01460 0.04410  -0.01890 1570 SER A CB  
1583 O  OG  . SER A 111 ? 0.23490 0.20510 0.17920 -0.01520 0.03360  -0.01400 1570 SER A OG  
1589 N  N   . VAL A 112 ? 0.17600 0.15360 0.14600 -0.00290 -0.01230 -0.00970 1571 VAL A N   
1590 C  CA  A VAL A 112 ? 0.18010 0.14640 0.14010 -0.00400 -0.01700 0.00160  1571 VAL A CA  
1591 C  CA  B VAL A 112 ? 0.17750 0.15020 0.13610 -0.00630 -0.01670 -0.00490 1571 VAL A CA  
1592 C  C   . VAL A 112 ? 0.16900 0.14050 0.12490 -0.00610 -0.00900 -0.00660 1571 VAL A C   
1593 O  O   . VAL A 112 ? 0.18170 0.13420 0.15350 -0.00340 0.00790  -0.00810 1571 VAL A O   
1594 C  CB  A VAL A 112 ? 0.19330 0.15070 0.15790 0.00330  -0.02670 0.01250  1571 VAL A CB  
1595 C  CB  B VAL A 112 ? 0.18720 0.15940 0.14740 -0.00610 -0.03060 -0.00360 1571 VAL A CB  
1596 C  CG1 A VAL A 112 ? 0.18670 0.15250 0.15290 0.00490  -0.00840 0.02990  1571 VAL A CG1 
1597 C  CG1 B VAL A 112 ? 0.20180 0.16260 0.15380 -0.00350 -0.02000 -0.00340 1571 VAL A CG1 
1598 C  CG2 A VAL A 112 ? 0.22130 0.15700 0.17150 0.00580  -0.02180 0.00570  1571 VAL A CG2 
1599 C  CG2 B VAL A 112 ? 0.19410 0.16610 0.14700 -0.00740 -0.03520 -0.00430 1571 VAL A CG2 
1618 N  N   . VAL A 113 ? 0.16960 0.13980 0.13660 -0.00670 -0.00520 -0.00270 1572 VAL A N   
1619 C  CA  . VAL A 113 ? 0.19600 0.14730 0.14620 -0.00080 -0.01220 -0.00490 1572 VAL A CA  
1620 C  C   . VAL A 113 ? 0.19230 0.14510 0.13500 0.00240  -0.01310 -0.00570 1572 VAL A C   
1621 O  O   . VAL A 113 ? 0.20340 0.14520 0.13110 0.00660  0.00340  -0.01040 1572 VAL A O   
1622 C  CB  . VAL A 113 ? 0.21200 0.15670 0.16950 0.02160  -0.01390 -0.01830 1572 VAL A CB  
1623 C  CG1 . VAL A 113 ? 0.23960 0.16920 0.16660 0.01810  -0.02690 -0.01930 1572 VAL A CG1 
1624 C  CG2 . VAL A 113 ? 0.21060 0.15510 0.18610 0.01940  -0.01400 -0.01870 1572 VAL A CG2 
1634 N  N   . GLN A 114 ? 0.18720 0.14520 0.12820 -0.00210 0.00810  -0.00210 1573 GLN A N   
1635 C  CA  . GLN A 114 ? 0.18510 0.14750 0.12450 -0.01280 0.01300  0.00080  1573 GLN A CA  
1636 C  C   . GLN A 114 ? 0.17100 0.13120 0.11240 -0.01640 0.01290  0.01000  1573 GLN A C   
1637 O  O   . GLN A 114 ? 0.17730 0.12700 0.14010 -0.00790 0.00180  0.00790  1573 GLN A O   
1638 C  CB  . GLN A 114 ? 0.19080 0.16920 0.13940 -0.02310 0.02180  0.00520  1573 GLN A CB  
1639 C  CG  . GLN A 114 ? 0.22930 0.19180 0.18350 -0.02850 0.03100  0.00390  1573 GLN A CG  
1640 C  CD  . GLN A 114 ? 0.27940 0.21950 0.23370 -0.02320 0.05160  0.01610  1573 GLN A CD  
1641 O  OE1 . GLN A 114 ? 0.28870 0.22680 0.25180 -0.02310 0.05390  0.00930  1573 GLN A OE1 
1642 N  NE2 . GLN A 114 ? 0.31280 0.23230 0.28600 -0.02040 0.06280  0.01750  1573 GLN A NE2 
1651 N  N   . TRP A 115 ? 0.16400 0.13120 0.10190 -0.01120 0.00640  0.01160  1574 TRP A N   
1652 C  CA  . TRP A 115 ? 0.15060 0.13530 0.10050 0.00090  -0.00760 0.00720  1574 TRP A CA  
1653 C  C   . TRP A 115 ? 0.15050 0.13830 0.12790 0.00290  -0.01550 0.00610  1574 TRP A C   
1654 O  O   . TRP A 115 ? 0.15360 0.14340 0.13280 0.01070  0.00360  0.00760  1574 TRP A O   
1655 C  CB  . TRP A 115 ? 0.15570 0.14220 0.10500 0.01470  -0.00210 0.00410  1574 TRP A CB  
1656 C  CG  . TRP A 115 ? 0.15400 0.14110 0.11330 -0.00030 0.00010  0.00040  1574 TRP A CG  
1657 C  CD1 . TRP A 115 ? 0.17050 0.14680 0.12370 0.00150  0.00750  0.01060  1574 TRP A CD1 
1658 C  CD2 . TRP A 115 ? 0.16000 0.13170 0.11210 -0.00090 -0.00590 -0.00220 1574 TRP A CD2 
1659 N  NE1 . TRP A 115 ? 0.16560 0.14520 0.12560 0.00770  0.00550  0.01440  1574 TRP A NE1 
1660 C  CE2 . TRP A 115 ? 0.15820 0.13310 0.11650 0.00380  -0.00460 0.00560  1574 TRP A CE2 
1661 C  CE3 . TRP A 115 ? 0.15420 0.12610 0.11910 0.00140  -0.00960 0.00400  1574 TRP A CE3 
1662 C  CZ2 . TRP A 115 ? 0.14650 0.13340 0.12660 0.01300  -0.00750 0.00370  1574 TRP A CZ2 
1663 C  CZ3 . TRP A 115 ? 0.15580 0.12370 0.13410 0.00350  -0.00470 -0.00950 1574 TRP A CZ3 
1664 C  CH2 . TRP A 115 ? 0.15230 0.12870 0.14040 0.01170  -0.01050 -0.00020 1574 TRP A CH2 
1675 N  N   . MET A 116 ? 0.15820 0.14120 0.13030 0.00440  -0.01870 0.00110  1575 MET A N   
1676 C  CA  A MET A 116 ? 0.18410 0.14550 0.16280 0.00230  -0.01570 0.00590  1575 MET A CA  
1677 C  CA  B MET A 116 ? 0.16530 0.14010 0.13520 0.00370  -0.01280 0.00290  1575 MET A CA  
1678 C  C   . MET A 116 ? 0.17720 0.13810 0.14270 -0.00100 -0.01030 -0.00100 1575 MET A C   
1679 O  O   . MET A 116 ? 0.18030 0.14740 0.15630 -0.01060 -0.00400 0.00410  1575 MET A O   
1680 C  CB  A MET A 116 ? 0.21320 0.15360 0.20770 0.00220  -0.01960 0.01150  1575 MET A CB  
1681 C  CB  B MET A 116 ? 0.15920 0.14020 0.12910 0.00680  -0.01070 0.00270  1575 MET A CB  
1682 C  CG  A MET A 116 ? 0.25000 0.16110 0.25520 -0.00030 -0.01810 0.01760  1575 MET A CG  
1683 C  CG  B MET A 116 ? 0.17470 0.14440 0.13200 0.00660  -0.00210 0.00020  1575 MET A CG  
1684 S  SD  A MET A 116 ? 0.27340 0.16800 0.30030 -0.00520 -0.02110 0.02750  1575 MET A SD  
1685 S  SD  B MET A 116 ? 0.20610 0.14800 0.16940 -0.00340 -0.00060 0.00340  1575 MET A SD  
1686 C  CE  A MET A 116 ? 0.28220 0.16390 0.30340 -0.01060 -0.00700 0.03590  1575 MET A CE  
1687 C  CE  B MET A 116 ? 0.17840 0.14470 0.12350 -0.00620 -0.00380 0.00770  1575 MET A CE  
1706 N  N   . GLU A 117 ? 0.17310 0.12940 0.12350 -0.00060 -0.01000 0.00360  1576 GLU A N   
1707 C  CA  . GLU A 117 ? 0.19540 0.13730 0.11320 -0.00370 -0.01390 0.00720  1576 GLU A CA  
1708 C  C   . GLU A 117 ? 0.18560 0.13870 0.10400 0.00030  -0.02120 0.00990  1576 GLU A C   
1709 O  O   . GLU A 117 ? 0.16730 0.14690 0.14960 0.00930  -0.01840 0.01230  1576 GLU A O   
1710 C  CB  . GLU A 117 ? 0.22890 0.14760 0.12460 -0.01420 -0.01480 0.00330  1576 GLU A CB  
1711 C  CG  . GLU A 117 ? 0.26020 0.16470 0.15530 -0.00570 -0.00970 -0.00580 1576 GLU A CG  
1712 C  CD  . GLU A 117 ? 0.29380 0.18700 0.17560 -0.01300 0.00560  -0.02600 1576 GLU A CD  
1713 O  OE1 . GLU A 117 ? 0.28640 0.19890 0.17820 -0.00830 0.00500  -0.03040 1576 GLU A OE1 
1714 O  OE2 . GLU A 117 ? 0.32800 0.20330 0.18670 -0.01480 0.01590  -0.02410 1576 GLU A OE2 
1721 N  N   . HIS A 118 ? 0.17490 0.13310 0.09040 -0.00520 -0.00560 0.00350  1577 HIS A N   
1722 C  CA  . HIS A 118 ? 0.17170 0.13680 0.10140 -0.00920 -0.00700 0.00630  1577 HIS A CA  
1723 C  C   . HIS A 118 ? 0.17470 0.13360 0.12230 -0.00350 -0.00880 0.01350  1577 HIS A C   
1724 O  O   . HIS A 118 ? 0.17790 0.13210 0.15010 0.00380  -0.01650 0.00970  1577 HIS A O   
1725 C  CB  . HIS A 118 ? 0.17870 0.14630 0.12150 -0.00770 -0.00310 0.01250  1577 HIS A CB  
1726 C  CG  . HIS A 118 ? 0.18980 0.15360 0.13470 -0.00890 0.00710  0.01160  1577 HIS A CG  
1727 N  ND1 . HIS A 118 ? 0.19050 0.15460 0.13930 -0.02210 0.01140  0.01360  1577 HIS A ND1 
1728 C  CD2 . HIS A 118 ? 0.19560 0.16030 0.13880 -0.01230 0.01120  0.00970  1577 HIS A CD2 
1729 C  CE1 . HIS A 118 ? 0.19180 0.16130 0.14030 -0.03050 0.00370  0.00970  1577 HIS A CE1 
1730 N  NE2 . HIS A 118 ? 0.18570 0.16460 0.13580 -0.02640 0.02310  0.00060  1577 HIS A NE2 
1738 N  N   . PHE A 119 ? 0.15600 0.13160 0.12060 -0.00820 -0.00740 0.01640  1578 PHE A N   
1739 C  CA  . PHE A 119 ? 0.15160 0.13200 0.12800 -0.00680 -0.00040 0.00810  1578 PHE A CA  
1740 C  C   . PHE A 119 ? 0.15390 0.13780 0.14490 -0.00920 -0.01280 0.01000  1578 PHE A C   
1741 O  O   . PHE A 119 ? 0.15690 0.14680 0.16090 -0.00710 -0.01660 0.00030  1578 PHE A O   
1742 C  CB  . PHE A 119 ? 0.15790 0.13330 0.14900 -0.00600 0.01490  0.00900  1578 PHE A CB  
1743 C  CG  . PHE A 119 ? 0.16080 0.13660 0.13310 0.00330  0.01030  0.00910  1578 PHE A CG  
1744 C  CD1 . PHE A 119 ? 0.16660 0.15030 0.10930 0.00670  0.01600  0.01200  1578 PHE A CD1 
1745 C  CD2 . PHE A 119 ? 0.15880 0.12690 0.12850 -0.00950 0.01330  0.01570  1578 PHE A CD2 
1746 C  CE1 . PHE A 119 ? 0.17000 0.14980 0.12450 0.00760  0.01080  0.02410  1578 PHE A CE1 
1747 C  CE2 . PHE A 119 ? 0.16910 0.12880 0.13140 -0.00990 0.02470  0.01490  1578 PHE A CE2 
1748 C  CZ  . PHE A 119 ? 0.17790 0.13930 0.13630 0.00190  0.01890  0.01760  1578 PHE A CZ  
1758 N  N   . GLU A 120 ? 0.16080 0.14630 0.15390 -0.00570 -0.02400 0.02010  1579 GLU A N   
1759 C  CA  . GLU A 120 ? 0.17310 0.16060 0.16250 -0.00520 -0.03330 0.01000  1579 GLU A CA  
1760 C  C   . GLU A 120 ? 0.17740 0.17160 0.18520 -0.00480 -0.03960 0.01820  1579 GLU A C   
1761 O  O   . GLU A 120 ? 0.17980 0.18440 0.24150 0.00120  -0.05020 0.02790  1579 GLU A O   
1762 C  CB  . GLU A 120 ? 0.20340 0.17080 0.17590 -0.00560 -0.03330 -0.00180 1579 GLU A CB  
1763 C  CG  . GLU A 120 ? 0.23830 0.17850 0.20250 -0.01610 -0.02230 -0.01180 1579 GLU A CG  
1764 C  CD  . GLU A 120 ? 0.28310 0.18220 0.23630 -0.02330 -0.00210 -0.01880 1579 GLU A CD  
1765 O  OE1 . GLU A 120 ? 0.29270 0.18450 0.23430 -0.02440 -0.01050 -0.01980 1579 GLU A OE1 
1766 O  OE2 . GLU A 120 ? 0.31450 0.18480 0.27680 -0.01720 0.00680  -0.02280 1579 GLU A OE2 
1773 N  N   . THR A 121 ? 0.18240 0.16970 0.15590 -0.00090 -0.04580 0.01480  1580 THR A N   
1774 C  CA  . THR A 121 ? 0.19940 0.16100 0.14850 0.00580  -0.03030 0.01420  1580 THR A CA  
1775 C  C   . THR A 121 ? 0.17910 0.15520 0.13020 0.01200  -0.02030 0.01610  1580 THR A C   
1776 O  O   . THR A 121 ? 0.18310 0.15410 0.17150 0.01940  -0.01880 0.01590  1580 THR A O   
1777 C  CB  . THR A 121 ? 0.21960 0.15160 0.14350 0.00990  -0.02840 0.02350  1580 THR A CB  
1778 O  OG1 . THR A 121 ? 0.20750 0.14340 0.15190 -0.00030 -0.01740 0.01330  1580 THR A OG1 
1779 C  CG2 . THR A 121 ? 0.24630 0.15860 0.17080 0.01420  -0.03070 0.02980  1580 THR A CG2 
1787 N  N   . TRP A 122 ? 0.17400 0.15540 0.12090 0.00320  -0.00010 0.01810  1581 TRP A N   
1788 C  CA  . TRP A 122 ? 0.16300 0.15610 0.12590 -0.00180 -0.00420 0.01280  1581 TRP A CA  
1789 C  C   . TRP A 122 ? 0.16050 0.16090 0.14360 -0.00350 -0.00670 0.01700  1581 TRP A C   
1790 O  O   . TRP A 122 ? 0.15890 0.16560 0.15490 -0.00890 0.00040  0.01660  1581 TRP A O   
1791 C  CB  . TRP A 122 ? 0.14500 0.14820 0.13810 -0.00530 -0.02550 0.00790  1581 TRP A CB  
1792 C  CG  . TRP A 122 ? 0.14100 0.14320 0.14040 0.00860  -0.02570 0.00990  1581 TRP A CG  
1793 C  CD1 . TRP A 122 ? 0.14300 0.14280 0.14260 0.00080  -0.02000 0.01460  1581 TRP A CD1 
1794 C  CD2 . TRP A 122 ? 0.13730 0.14250 0.11740 0.00980  -0.01610 0.01880  1581 TRP A CD2 
1795 N  NE1 . TRP A 122 ? 0.13590 0.14190 0.12400 0.00930  -0.00580 0.01280  1581 TRP A NE1 
1796 C  CE2 . TRP A 122 ? 0.13230 0.14070 0.11100 0.01310  -0.01480 0.01410  1581 TRP A CE2 
1797 C  CE3 . TRP A 122 ? 0.15190 0.14160 0.12600 0.00260  0.00330  0.01730  1581 TRP A CE3 
1798 C  CZ2 . TRP A 122 ? 0.14930 0.14020 0.12080 0.01600  -0.01450 0.01240  1581 TRP A CZ2 
1799 C  CZ3 . TRP A 122 ? 0.15360 0.14270 0.13800 0.00020  -0.00560 0.01980  1581 TRP A CZ3 
1800 C  CH2 . TRP A 122 ? 0.15910 0.14340 0.12430 0.00260  -0.00900 0.02270  1581 TRP A CH2 
1811 N  N   . PRO A 123 ? 0.14610 0.15900 0.14760 -0.00270 -0.01540 0.02390  1582 PRO A N   
1812 C  CA  . PRO A 123 ? 0.15570 0.16940 0.15460 0.00370  -0.03100 0.02490  1582 PRO A CA  
1813 C  C   . PRO A 123 ? 0.15400 0.18330 0.16430 -0.00520 -0.01410 0.01360  1582 PRO A C   
1814 O  O   . PRO A 123 ? 0.16260 0.18090 0.16890 -0.00620 0.00050  0.00910  1582 PRO A O   
1815 C  CB  . PRO A 123 ? 0.17320 0.16790 0.15400 0.00390  -0.03270 0.02780  1582 PRO A CB  
1816 C  CG  . PRO A 123 ? 0.16520 0.16550 0.16740 0.01040  -0.01780 0.02290  1582 PRO A CG  
1817 C  CD  . PRO A 123 ? 0.14290 0.15680 0.15730 0.00150  -0.00840 0.02960  1582 PRO A CD  
1825 N  N   . SER A 124 ? 0.17370 0.20520 0.19420 -0.02470 -0.00020 0.00940  1583 SER A N   
1826 C  CA  . SER A 124 ? 0.21330 0.22530 0.23190 -0.04080 0.00380  -0.00140 1583 SER A CA  
1827 C  C   . SER A 124 ? 0.19900 0.21950 0.21080 -0.04060 0.01640  0.00550  1583 SER A C   
1828 O  O   . SER A 124 ? 0.22760 0.22030 0.22220 -0.04090 0.04000  0.00680  1583 SER A O   
1829 C  CB  . SER A 124 ? 0.26600 0.25340 0.28850 -0.05180 -0.00360 -0.01180 1583 SER A CB  
1830 O  OG  . SER A 124 ? 0.28670 0.27140 0.31980 -0.06420 -0.02170 -0.02170 1583 SER A OG  
1836 N  N   . HIS A 125 ? 0.16800 0.21200 0.18750 -0.03450 0.00420  -0.00060 1584 HIS A N   
1837 C  CA  . HIS A 125 ? 0.16610 0.20640 0.17750 -0.02200 -0.00200 0.00430  1584 HIS A CA  
1838 C  C   . HIS A 125 ? 0.14920 0.18230 0.15000 -0.01440 0.00190  0.00730  1584 HIS A C   
1839 O  O   . HIS A 125 ? 0.15810 0.19030 0.17120 -0.01490 0.01250  0.00280  1584 HIS A O   
1840 C  CB  . HIS A 125 ? 0.16100 0.22580 0.18480 -0.00230 0.00090  0.00400  1584 HIS A CB  
1841 C  CG  . HIS A 125 ? 0.17790 0.23920 0.17810 0.02370  0.00650  0.01310  1584 HIS A CG  
1842 N  ND1 . HIS A 125 ? 0.19540 0.24550 0.18190 0.03380  0.00180  0.01610  1584 HIS A ND1 
1843 C  CD2 . HIS A 125 ? 0.19000 0.24520 0.18170 0.03270  0.00200  0.02290  1584 HIS A CD2 
1844 C  CE1 . HIS A 125 ? 0.18930 0.24800 0.17780 0.04050  -0.00080 0.02330  1584 HIS A CE1 
1845 N  NE2 . HIS A 125 ? 0.18630 0.24780 0.17700 0.04070  0.00350  0.02750  1584 HIS A NE2 
1853 N  N   . LEU A 126 ? 0.12550 0.15130 0.12980 -0.01000 0.01010  0.01960  1585 LEU A N   
1854 C  CA  . LEU A 126 ? 0.13590 0.14170 0.13200 -0.00330 0.00200  0.01990  1585 LEU A CA  
1855 C  C   . LEU A 126 ? 0.13590 0.12730 0.13570 -0.00050 -0.01560 0.01280  1585 LEU A C   
1856 O  O   . LEU A 126 ? 0.17130 0.12900 0.14820 0.00720  -0.02430 0.00240  1585 LEU A O   
1857 C  CB  . LEU A 126 ? 0.15200 0.14250 0.14270 -0.00410 -0.01680 0.02020  1585 LEU A CB  
1858 C  CG  . LEU A 126 ? 0.15380 0.14600 0.16060 -0.00060 -0.01190 0.02380  1585 LEU A CG  
1859 C  CD1 . LEU A 126 ? 0.16460 0.13930 0.16070 -0.00480 -0.00680 0.02420  1585 LEU A CD1 
1860 C  CD2 . LEU A 126 ? 0.14340 0.14940 0.18510 0.00140  0.00280  0.02390  1585 LEU A CD2 
1872 N  N   . PRO A 127 ? 0.14260 0.12100 0.13400 0.00370  -0.00620 0.01120  1586 PRO A N   
1873 C  CA  . PRO A 127 ? 0.13720 0.12280 0.13120 0.00220  -0.00610 0.01410  1586 PRO A CA  
1874 C  C   . PRO A 127 ? 0.12960 0.12200 0.13140 -0.00160 -0.01050 0.00780  1586 PRO A C   
1875 O  O   . PRO A 127 ? 0.13130 0.12610 0.14220 -0.00580 0.00220  0.00230  1586 PRO A O   
1876 C  CB  . PRO A 127 ? 0.14140 0.12490 0.13940 -0.00180 0.00370  0.00830  1586 PRO A CB  
1877 C  CG  . PRO A 127 ? 0.15370 0.12630 0.15090 0.00130  0.01560  0.00740  1586 PRO A CG  
1878 C  CD  . PRO A 127 ? 0.15210 0.12480 0.15110 0.00300  0.01090  0.00770  1586 PRO A CD  
1886 N  N   . ILE A 128 ? 0.12520 0.11970 0.12590 -0.00340 -0.00990 0.00260  1587 ILE A N   
1887 C  CA  A ILE A 128 ? 0.12660 0.12040 0.11430 -0.00300 -0.00250 0.00900  1587 ILE A CA  
1888 C  CA  B ILE A 128 ? 0.12730 0.12210 0.12190 -0.00750 -0.00230 0.00970  1587 ILE A CA  
1889 C  C   . ILE A 128 ? 0.12760 0.11930 0.11120 0.00040  0.00270  0.01820  1587 ILE A C   
1890 O  O   . ILE A 128 ? 0.12690 0.12110 0.13120 -0.00010 -0.00340 0.02080  1587 ILE A O   
1891 C  CB  A ILE A 128 ? 0.12420 0.12180 0.11210 -0.00380 -0.00260 0.00840  1587 ILE A CB  
1892 C  CB  B ILE A 128 ? 0.13520 0.12430 0.13760 -0.00600 -0.00400 -0.00040 1587 ILE A CB  
1893 C  CG1 A ILE A 128 ? 0.12260 0.12260 0.11250 -0.00490 -0.00350 0.00780  1587 ILE A CG1 
1894 C  CG1 B ILE A 128 ? 0.14670 0.13350 0.15030 -0.00990 -0.01390 -0.00650 1587 ILE A CG1 
1895 C  CG2 A ILE A 128 ? 0.12380 0.12240 0.11250 -0.00490 -0.00300 0.00750  1587 ILE A CG2 
1896 C  CG2 B ILE A 128 ? 0.14490 0.12690 0.16410 -0.01000 -0.00540 -0.01140 1587 ILE A CG2 
1897 C  CD1 A ILE A 128 ? 0.12270 0.12290 0.11230 -0.00560 -0.00330 0.00760  1587 ILE A CD1 
1898 C  CD1 B ILE A 128 ? 0.17220 0.14070 0.14870 -0.01090 -0.02330 0.00330  1587 ILE A CD1 
1921 N  N   . VAL A 129 ? 0.11880 0.11210 0.11850 0.00150  -0.00730 0.02780  1588 VAL A N   
1922 C  CA  . VAL A 129 ? 0.12080 0.11540 0.12030 0.00970  0.00420  0.01780  1588 VAL A CA  
1923 C  C   . VAL A 129 ? 0.11570 0.11460 0.10490 -0.00110 0.00490  0.01100  1588 VAL A C   
1924 O  O   . VAL A 129 ? 0.13400 0.11480 0.12490 0.00250  0.00700  0.01270  1588 VAL A O   
1925 C  CB  . VAL A 129 ? 0.13930 0.12330 0.13140 0.01370  0.01100  0.00050  1588 VAL A CB  
1926 C  CG1 . VAL A 129 ? 0.15490 0.11660 0.14310 0.01770  0.02670  -0.00760 1588 VAL A CG1 
1927 C  CG2 . VAL A 129 ? 0.14880 0.13580 0.16440 0.00180  0.01590  -0.00640 1588 VAL A CG2 
1937 N  N   . ALA A 130 ? 0.11640 0.12170 0.10930 0.00260  -0.00950 0.00390  1589 ALA A N   
1938 C  CA  . ALA A 130 ? 0.12150 0.12720 0.09480 0.01250  -0.00650 -0.00780 1589 ALA A CA  
1939 C  C   . ALA A 130 ? 0.12360 0.12690 0.08770 0.00850  -0.00320 -0.00330 1589 ALA A C   
1940 O  O   . ALA A 130 ? 0.12290 0.13050 0.10400 0.01410  -0.00450 0.00560  1589 ALA A O   
1941 C  CB  . ALA A 130 ? 0.14470 0.13100 0.11140 0.01620  -0.01900 -0.01760 1589 ALA A CB  
1947 N  N   . HIS A 131 ? 0.11850 0.12630 0.10600 0.00190  -0.00310 -0.01020 1590 HIS A N   
1948 C  CA  . HIS A 131 ? 0.12340 0.12290 0.11480 0.00790  -0.00200 -0.00860 1590 HIS A CA  
1949 C  C   . HIS A 131 ? 0.12440 0.12350 0.10420 0.01490  -0.00580 -0.00450 1590 HIS A C   
1950 O  O   . HIS A 131 ? 0.15040 0.12270 0.11670 0.00700  0.00020  -0.00110 1590 HIS A O   
1951 C  CB  . HIS A 131 ? 0.13010 0.12670 0.11900 -0.00350 0.00910  -0.01590 1590 HIS A CB  
1952 C  CG  . HIS A 131 ? 0.11910 0.12230 0.13090 -0.00210 0.00060  -0.01810 1590 HIS A CG  
1953 N  ND1 . HIS A 131 ? 0.11340 0.12910 0.14490 0.00220  0.00950  -0.01350 1590 HIS A ND1 
1954 C  CD2 . HIS A 131 ? 0.12270 0.12510 0.16250 -0.00180 -0.00850 -0.00690 1590 HIS A CD2 
1955 C  CE1 . HIS A 131 ? 0.09400 0.12810 0.16480 0.00550  -0.00380 0.00330  1590 HIS A CE1 
1956 N  NE2 . HIS A 131 ? 0.11420 0.13010 0.17050 0.00330  -0.01080 -0.00140 1590 HIS A NE2 
1964 N  N   . ALA A 132 ? 0.12520 0.12110 0.10200 0.00680  0.00340  -0.01290 1591 ALA A N   
1965 C  CA  . ALA A 132 ? 0.13860 0.12430 0.11270 0.01540  0.00640  -0.01070 1591 ALA A CA  
1966 C  C   . ALA A 132 ? 0.15850 0.14470 0.12470 0.02940  0.03100  0.01060  1591 ALA A C   
1967 O  O   . ALA A 132 ? 0.19250 0.17110 0.16200 0.05760  0.03940  0.03130  1591 ALA A O   
1968 C  CB  . ALA A 132 ? 0.12610 0.11860 0.13490 0.01040  -0.00080 -0.01170 1591 ALA A CB  
1974 N  N   . GLU A 133 ? 0.14960 0.13610 0.12790 0.01830  -0.00190 0.00300  1592 GLU A N   
1975 C  CA  . GLU A 133 ? 0.14250 0.12790 0.13410 0.01310  -0.01670 -0.00760 1592 GLU A CA  
1976 C  C   . GLU A 133 ? 0.14760 0.12280 0.12430 0.02100  -0.01850 -0.00200 1592 GLU A C   
1977 O  O   . GLU A 133 ? 0.14600 0.12580 0.12560 0.01330  -0.01850 -0.01060 1592 GLU A O   
1978 C  CB  . GLU A 133 ? 0.13470 0.12980 0.15520 0.00970  -0.03030 -0.01180 1592 GLU A CB  
1979 C  CG  . GLU A 133 ? 0.13390 0.14020 0.16380 0.00160  -0.01400 -0.01450 1592 GLU A CG  
1980 C  CD  . GLU A 133 ? 0.13240 0.15470 0.18910 0.01090  0.00090  0.00300  1592 GLU A CD  
1981 O  OE1 . GLU A 133 ? 0.14890 0.17140 0.18240 -0.00640 -0.02490 0.01410  1592 GLU A OE1 
1982 O  OE2 . GLU A 133 ? 0.14410 0.16140 0.21450 0.01580  -0.00340 0.00510  1592 GLU A OE2 
1989 N  N   . GLN A 134 ? 0.17410 0.12170 0.14600 0.01120  -0.00600 -0.00700 1593 GLN A N   
1990 C  CA  . GLN A 134 ? 0.17300 0.12420 0.14520 0.00790  -0.00910 -0.00440 1593 GLN A CA  
1991 C  C   . GLN A 134 ? 0.17490 0.13610 0.15760 0.01090  -0.00690 0.01070  1593 GLN A C   
1992 O  O   . GLN A 134 ? 0.16710 0.11700 0.17120 0.01930  0.00440  0.00980  1593 GLN A O   
1993 C  CB  . GLN A 134 ? 0.18330 0.14740 0.17630 0.01400  -0.03580 -0.00870 1593 GLN A CB  
1994 C  CG  . GLN A 134 ? 0.19650 0.16790 0.20210 0.01770  -0.03750 -0.01180 1593 GLN A CG  
1995 C  CD  . GLN A 134 ? 0.20760 0.18770 0.23570 0.02070  -0.04180 0.00660  1593 GLN A CD  
1996 O  OE1 . GLN A 134 ? 0.19660 0.20120 0.26770 0.02240  -0.01800 0.00640  1593 GLN A OE1 
1997 N  NE2 . GLN A 134 ? 0.22310 0.19120 0.26200 0.04110  -0.04580 0.00950  1593 GLN A NE2 
2006 N  N   . GLN A 135 ? 0.37720 0.36570 0.37860 0.00030  -0.00010 0.00020  1594 GLN A N   
2007 C  CA  . GLN A 135 ? 0.38060 0.38010 0.38060 0.00000  0.00000  0.00000  1594 GLN A CA  
2008 C  C   . GLN A 135 ? 0.37680 0.36640 0.37840 -0.00010 -0.00000 0.00010  1594 GLN A C   
2009 O  O   . GLN A 135 ? 0.38030 0.37980 0.38040 0.00010  0.00000  0.00000  1594 GLN A O   
2010 C  CB  . GLN A 135 ? 0.38060 0.38070 0.38060 -0.00000 -0.00000 -0.00000 1594 GLN A CB  
2011 C  CG  . GLN A 135 ? 0.38080 0.38080 0.38080 0.00000  -0.00010 -0.00010 1594 GLN A CG  
2012 C  CD  . GLN A 135 ? 0.38070 0.38080 0.38080 0.00020  0.00010  -0.00000 1594 GLN A CD  
2013 O  OE1 . GLN A 135 ? 0.38050 0.38050 0.38060 0.00010  0.00010  -0.00010 1594 GLN A OE1 
2014 N  NE2 . GLN A 135 ? 0.38090 0.38090 0.38080 0.00010  -0.00010 -0.00000 1594 GLN A NE2 
2023 N  N   . THR A 136 ? 0.13710 0.14100 0.14310 -0.00430 -0.00960 0.00310  1595 THR A N   
2024 C  CA  . THR A 136 ? 0.14780 0.12410 0.13010 -0.00430 -0.00910 -0.00050 1595 THR A CA  
2025 C  C   . THR A 136 ? 0.15590 0.11550 0.11270 0.00170  -0.01500 0.00150  1595 THR A C   
2026 O  O   . THR A 136 ? 0.16420 0.11440 0.12220 0.00030  -0.01520 0.00850  1595 THR A O   
2027 C  CB  . THR A 136 ? 0.15370 0.12850 0.12350 -0.01050 -0.01770 -0.00150 1595 THR A CB  
2028 O  OG1 . THR A 136 ? 0.14870 0.13080 0.13720 0.00180  -0.01450 0.00740  1595 THR A OG1 
2029 C  CG2 . THR A 136 ? 0.17250 0.12560 0.12200 -0.01360 -0.02050 -0.01210 1595 THR A CG2 
2037 N  N   . VAL A 137 ? 0.15280 0.11310 0.12940 0.00720  -0.01950 0.01150  1596 VAL A N   
2038 C  CA  A VAL A 137 ? 0.15340 0.11130 0.12910 0.00880  -0.01390 0.00610  1596 VAL A CA  
2039 C  CA  B VAL A 137 ? 0.15750 0.11700 0.13090 0.01690  -0.01040 0.00460  1596 VAL A CA  
2040 C  C   . VAL A 137 ? 0.15340 0.11130 0.12900 0.01300  -0.01910 0.00330  1596 VAL A C   
2041 O  O   . VAL A 137 ? 0.15300 0.10910 0.13340 0.01110  -0.01260 0.00930  1596 VAL A O   
2042 C  CB  A VAL A 137 ? 0.15550 0.10810 0.13460 0.00560  -0.00760 -0.00180 1596 VAL A CB  
2043 C  CB  B VAL A 137 ? 0.16870 0.12500 0.14380 0.02600  -0.00630 -0.00630 1596 VAL A CB  
2044 C  CG1 A VAL A 137 ? 0.15930 0.10650 0.14380 0.00540  -0.00130 -0.00260 1596 VAL A CG1 
2045 C  CG1 B VAL A 137 ? 0.18930 0.12690 0.14380 0.02400  0.01970  -0.00550 1596 VAL A CG1 
2046 C  CG2 A VAL A 137 ? 0.16370 0.10690 0.13210 0.00290  0.00290  -0.01160 1596 VAL A CG2 
2047 C  CG2 B VAL A 137 ? 0.16600 0.12680 0.13970 0.03190  -0.01060 -0.02200 1596 VAL A CG2 
2066 N  N   . ALA A 138 ? 0.15720 0.10960 0.13990 0.00550  -0.02060 -0.00270 1597 ALA A N   
2067 C  CA  . ALA A 138 ? 0.14570 0.10780 0.12850 0.00200  -0.02240 -0.00080 1597 ALA A CA  
2068 C  C   . ALA A 138 ? 0.13500 0.10680 0.12620 -0.00330 -0.01390 -0.00550 1597 ALA A C   
2069 O  O   . ALA A 138 ? 0.13180 0.10980 0.14330 -0.00160 -0.00660 -0.00840 1597 ALA A O   
2070 C  CB  . ALA A 138 ? 0.16580 0.11110 0.12700 0.00160  -0.02600 0.00600  1597 ALA A CB  
2076 N  N   . ALA A 139 ? 0.13200 0.10640 0.12600 -0.00250 -0.00200 -0.00880 1598 ALA A N   
2077 C  CA  . ALA A 139 ? 0.13800 0.10100 0.12080 -0.00450 0.00520  -0.00840 1598 ALA A CA  
2078 C  C   . ALA A 139 ? 0.13450 0.10210 0.11870 0.00680  -0.00010 -0.00560 1598 ALA A C   
2079 O  O   . ALA A 139 ? 0.14380 0.10550 0.13150 0.00100  -0.00840 -0.00710 1598 ALA A O   
2080 C  CB  . ALA A 139 ? 0.14370 0.09840 0.13390 -0.00560 0.00460  -0.00180 1598 ALA A CB  
2086 N  N   . VAL A 140 ? 0.12100 0.10200 0.12310 0.00600  0.00480  -0.00170 1599 VAL A N   
2087 C  CA  . VAL A 140 ? 0.12980 0.10450 0.11340 0.00630  0.00550  -0.00760 1599 VAL A CA  
2088 C  C   . VAL A 140 ? 0.13070 0.11370 0.10050 0.01300  -0.00590 0.00090  1599 VAL A C   
2089 O  O   . VAL A 140 ? 0.12990 0.11530 0.14220 0.01190  -0.01240 0.00040  1599 VAL A O   
2090 C  CB  . VAL A 140 ? 0.13290 0.10090 0.13340 0.00650  -0.00130 -0.01300 1599 VAL A CB  
2091 C  CG1 . VAL A 140 ? 0.13910 0.10030 0.13810 0.01910  0.00280  -0.01630 1599 VAL A CG1 
2092 C  CG2 . VAL A 140 ? 0.14780 0.09370 0.13700 -0.00320 -0.00100 -0.01790 1599 VAL A CG2 
2102 N  N   . LEU A 141 ? 0.12400 0.12310 0.10870 0.00600  0.00450  0.00430  1600 LEU A N   
2103 C  CA  . LEU A 141 ? 0.13420 0.13030 0.11160 0.00790  0.01610  -0.00720 1600 LEU A CA  
2104 C  C   . LEU A 141 ? 0.12940 0.12560 0.13050 0.00740  0.00390  -0.00550 1600 LEU A C   
2105 O  O   . LEU A 141 ? 0.13290 0.12520 0.13740 0.00650  -0.00760 -0.00200 1600 LEU A O   
2106 C  CB  . LEU A 141 ? 0.15260 0.14340 0.11950 0.00790  0.01140  -0.00710 1600 LEU A CB  
2107 C  CG  . LEU A 141 ? 0.22380 0.16420 0.17220 0.01270  0.03180  -0.00150 1600 LEU A CG  
2108 C  CD1 . LEU A 141 ? 0.24640 0.17700 0.20380 0.01330  0.02220  0.00680  1600 LEU A CD1 
2109 C  CD2 . LEU A 141 ? 0.26990 0.17130 0.19230 0.01840  0.04940  -0.01870 1600 LEU A CD2 
2121 N  N   . MET A 142 ? 0.12640 0.12210 0.13310 0.00040  -0.01160 -0.00610 1601 MET A N   
2122 C  CA  . MET A 142 ? 0.12460 0.12470 0.13730 -0.01190 0.00110  -0.01120 1601 MET A CA  
2123 C  C   . MET A 142 ? 0.13390 0.12430 0.12130 -0.00370 -0.01040 -0.01530 1601 MET A C   
2124 O  O   . MET A 142 ? 0.14700 0.12010 0.13490 -0.00490 -0.02010 -0.00110 1601 MET A O   
2125 C  CB  . MET A 142 ? 0.12240 0.13220 0.16020 -0.01140 0.00140  -0.00990 1601 MET A CB  
2126 C  CG  . MET A 142 ? 0.13780 0.13680 0.18660 -0.00560 -0.01190 -0.01300 1601 MET A CG  
2127 S  SD  . MET A 142 ? 0.18130 0.15180 0.23590 -0.00740 -0.00990 0.00130  1601 MET A SD  
2128 C  CE  . MET A 142 ? 0.20180 0.16620 0.25520 -0.01530 -0.02930 -0.00160 1601 MET A CE  
2138 N  N   . VAL A 143 ? 0.12600 0.13200 0.11110 -0.00200 0.00330  -0.00610 1602 VAL A N   
2139 C  CA  . VAL A 143 ? 0.13090 0.13650 0.11960 -0.01280 -0.00220 0.00860  1602 VAL A CA  
2140 C  C   . VAL A 143 ? 0.12720 0.13090 0.12280 -0.00480 -0.01800 0.00020  1602 VAL A C   
2141 O  O   . VAL A 143 ? 0.12860 0.12840 0.14780 -0.00640 -0.03880 -0.00240 1602 VAL A O   
2142 C  CB  . VAL A 143 ? 0.14230 0.14370 0.12510 -0.02510 -0.00290 0.00240  1602 VAL A CB  
2143 C  CG1 . VAL A 143 ? 0.15480 0.14390 0.14770 -0.02180 -0.00290 0.00340  1602 VAL A CG1 
2144 C  CG2 . VAL A 143 ? 0.14770 0.15630 0.13550 -0.01820 -0.01320 -0.00800 1602 VAL A CG2 
2154 N  N   . ALA A 144 ? 0.12640 0.12650 0.12610 0.00600  0.00220  -0.00480 1603 ALA A N   
2155 C  CA  . ALA A 144 ? 0.13240 0.12840 0.14200 0.00820  -0.00680 -0.00590 1603 ALA A CA  
2156 C  C   . ALA A 144 ? 0.13990 0.13130 0.13660 0.00940  -0.01240 -0.00420 1603 ALA A C   
2157 O  O   . ALA A 144 ? 0.13640 0.13530 0.14900 0.01270  -0.01910 -0.00150 1603 ALA A O   
2158 C  CB  . ALA A 144 ? 0.13840 0.12850 0.15240 0.00930  -0.01620 -0.01760 1603 ALA A CB  
2164 N  N   . GLN A 145 ? 0.13360 0.13200 0.13430 0.00410  -0.00820 -0.01630 1604 GLN A N   
2165 C  CA  . GLN A 145 ? 0.14000 0.14440 0.15210 -0.00020 -0.00060 -0.01320 1604 GLN A CA  
2166 C  C   . GLN A 145 ? 0.14500 0.14590 0.14460 -0.00690 -0.01360 -0.00650 1604 GLN A C   
2167 O  O   . GLN A 145 ? 0.13450 0.15160 0.17000 -0.00310 -0.03030 0.00030  1604 GLN A O   
2168 C  CB  . GLN A 145 ? 0.15200 0.15430 0.19280 0.00220  -0.00130 -0.01800 1604 GLN A CB  
2169 C  CG  . GLN A 145 ? 0.17650 0.15980 0.22030 0.01470  0.00770  -0.00780 1604 GLN A CG  
2170 C  CD  . GLN A 145 ? 0.18200 0.17040 0.24850 0.01920  0.00240  -0.00070 1604 GLN A CD  
2171 O  OE1 . GLN A 145 ? 0.18530 0.17270 0.26400 0.02400  0.00840  0.01000  1604 GLN A OE1 
2172 N  NE2 . GLN A 145 ? 0.17610 0.17620 0.24470 0.01650  0.00330  0.00740  1604 GLN A NE2 
2181 N  N   . LEU A 146 ? 0.16070 0.15040 0.16160 -0.01030 -0.01640 -0.01550 1605 LEU A N   
2182 C  CA  . LEU A 146 ? 0.17570 0.15240 0.15930 -0.01310 -0.00740 -0.01650 1605 LEU A CA  
2183 C  C   . LEU A 146 ? 0.20360 0.15160 0.15900 -0.00720 -0.01480 -0.02000 1605 LEU A C   
2184 O  O   . LEU A 146 ? 0.23250 0.15640 0.18700 -0.00890 -0.02720 -0.00830 1605 LEU A O   
2185 C  CB  . LEU A 146 ? 0.18010 0.15770 0.16850 -0.01070 0.00070  -0.01860 1605 LEU A CB  
2186 C  CG  . LEU A 146 ? 0.18490 0.16510 0.20620 -0.00050 0.00550  -0.02030 1605 LEU A CG  
2187 C  CD1 . LEU A 146 ? 0.18740 0.16790 0.21380 0.01760  0.02130  -0.01520 1605 LEU A CD1 
2188 C  CD2 . LEU A 146 ? 0.19210 0.16540 0.21400 -0.00990 -0.01640 -0.01370 1605 LEU A CD2 
2200 N  N   . THR A 147 ? 0.21390 0.15110 0.17240 -0.00800 -0.02680 -0.00820 1606 THR A N   
2201 C  CA  . THR A 147 ? 0.21690 0.15800 0.20010 0.00030  -0.04600 0.00580  1606 THR A CA  
2202 C  C   . THR A 147 ? 0.22190 0.16200 0.22110 0.00660  -0.05440 0.00480  1606 THR A C   
2203 O  O   . THR A 147 ? 0.23950 0.16460 0.26360 0.01240  -0.06620 0.02010  1606 THR A O   
2204 C  CB  . THR A 147 ? 0.20340 0.15840 0.20060 -0.00770 -0.04450 0.00760  1606 THR A CB  
2205 O  OG1 . THR A 147 ? 0.20020 0.15720 0.18810 -0.00750 -0.05000 0.02740  1606 THR A OG1 
2206 C  CG2 . THR A 147 ? 0.20820 0.16130 0.21630 -0.01970 -0.02880 0.01080  1606 THR A CG2 
2214 N  N   . GLN A 148 ? 0.20510 0.17300 0.21650 0.00240  -0.06590 -0.01830 1607 GLN A N   
2215 C  CA  A GLN A 148 ? 0.17270 0.17840 0.20490 0.00370  -0.05830 -0.03060 1607 GLN A CA  
2216 C  CA  B GLN A 148 ? 0.18430 0.17620 0.22060 0.00770  -0.06590 -0.03310 1607 GLN A CA  
2217 C  C   . GLN A 148 ? 0.16330 0.16690 0.21260 0.01270  -0.05930 -0.02980 1607 GLN A C   
2218 O  O   . GLN A 148 ? 0.17840 0.17610 0.24770 0.02390  -0.06820 -0.02980 1607 GLN A O   
2219 C  CB  A GLN A 148 ? 0.17350 0.19990 0.19610 0.00490  -0.03390 -0.03370 1607 GLN A CB  
2220 C  CB  B GLN A 148 ? 0.20470 0.19400 0.24720 0.01210  -0.05220 -0.04300 1607 GLN A CB  
2221 C  CG  A GLN A 148 ? 0.19290 0.22150 0.18770 -0.00140 -0.02320 -0.03810 1607 GLN A CG  
2222 C  CG  B GLN A 148 ? 0.22010 0.20860 0.25940 0.01140  -0.03010 -0.05080 1607 GLN A CG  
2223 C  CD  A GLN A 148 ? 0.20980 0.24560 0.19300 -0.00530 -0.02670 -0.04410 1607 GLN A CD  
2224 C  CD  B GLN A 148 ? 0.21830 0.22300 0.25760 0.00540  0.01000  -0.05050 1607 GLN A CD  
2225 O  OE1 A GLN A 148 ? 0.22980 0.25650 0.21880 -0.00080 -0.03590 -0.05120 1607 GLN A OE1 
2226 O  OE1 B GLN A 148 ? 0.25130 0.23320 0.29330 0.00960  0.00570  -0.05540 1607 GLN A OE1 
2227 N  NE2 A GLN A 148 ? 0.21140 0.25410 0.20080 -0.01360 -0.02080 -0.04130 1607 GLN A NE2 
2228 N  NE2 B GLN A 148 ? 0.17610 0.22590 0.22430 -0.00440 0.03930  -0.03690 1607 GLN A NE2 
2245 N  N   . ARG A 149 ? 0.14120 0.14640 0.17420 0.00870  -0.05040 -0.01830 1608 ARG A N   
2246 C  CA  . ARG A 149 ? 0.12330 0.13680 0.15140 0.01320  -0.02540 -0.01360 1608 ARG A CA  
2247 C  C   . ARG A 149 ? 0.13220 0.13380 0.13950 0.00330  -0.01620 -0.00600 1608 ARG A C   
2248 O  O   . ARG A 149 ? 0.13740 0.13430 0.14290 0.01000  -0.02690 -0.01810 1608 ARG A O   
2249 C  CB  . ARG A 149 ? 0.13020 0.13750 0.15890 0.00990  -0.03370 -0.00330 1608 ARG A CB  
2250 C  CG  . ARG A 149 ? 0.14270 0.13370 0.16190 0.01460  -0.02180 0.01250  1608 ARG A CG  
2251 C  CD  . ARG A 149 ? 0.15950 0.13360 0.16040 0.00910  -0.02450 0.01710  1608 ARG A CD  
2252 N  NE  . ARG A 149 ? 0.15410 0.13770 0.15810 -0.00060 -0.03660 0.01660  1608 ARG A NE  
2253 C  CZ  . ARG A 149 ? 0.16310 0.14670 0.15160 -0.00150 -0.02950 0.00850  1608 ARG A CZ  
2254 N  NH1 . ARG A 149 ? 0.17910 0.14990 0.14880 -0.00500 -0.01450 0.00120  1608 ARG A NH1 
2255 N  NH2 . ARG A 149 ? 0.16590 0.15150 0.14810 -0.01630 -0.02330 0.01550  1608 ARG A NH2 
2269 N  N   . SER A 150 ? 0.12930 0.13360 0.13560 -0.00120 -0.01180 -0.00980 1609 SER A N   
2270 C  CA  . SER A 150 ? 0.12680 0.12670 0.13030 -0.00230 -0.01470 -0.00780 1609 SER A CA  
2271 C  C   . SER A 150 ? 0.12490 0.11980 0.10850 -0.00830 -0.01420 -0.00320 1609 SER A C   
2272 O  O   . SER A 150 ? 0.13830 0.12080 0.13500 -0.00680 -0.01170 -0.00160 1609 SER A O   
2273 C  CB  . SER A 150 ? 0.13320 0.13430 0.15240 0.00370  -0.01080 -0.01630 1609 SER A CB  
2274 O  OG  . SER A 150 ? 0.16080 0.13860 0.19410 0.01130  -0.00230 -0.00810 1609 SER A OG  
2280 N  N   . VAL A 151 ? 0.12640 0.12480 0.11370 -0.00540 -0.00040 0.01120  1610 VAL A N   
2281 C  CA  . VAL A 151 ? 0.12430 0.12770 0.12370 -0.00210 -0.00320 -0.00110 1610 VAL A CA  
2282 C  C   . VAL A 151 ? 0.12340 0.12420 0.13080 -0.00470 -0.01840 0.00640  1610 VAL A C   
2283 O  O   . VAL A 151 ? 0.13210 0.12700 0.12160 -0.01590 -0.02410 0.00930  1610 VAL A O   
2284 C  CB  . VAL A 151 ? 0.12300 0.13390 0.14030 -0.00240 0.00740  -0.00510 1610 VAL A CB  
2285 C  CG1 . VAL A 151 ? 0.12820 0.13540 0.14940 0.00400  -0.01200 0.00570  1610 VAL A CG1 
2286 C  CG2 . VAL A 151 ? 0.12460 0.14210 0.16470 0.00050  0.02010  -0.01270 1610 VAL A CG2 
2296 N  N   . HIS A 152 ? 0.10900 0.11870 0.13690 -0.00450 -0.02640 0.00120  1611 HIS A N   
2297 C  CA  . HIS A 152 ? 0.11010 0.11760 0.12340 -0.00300 -0.00640 -0.00950 1611 HIS A CA  
2298 C  C   . HIS A 152 ? 0.10490 0.11880 0.10720 -0.00340 -0.00980 -0.00590 1611 HIS A C   
2299 O  O   . HIS A 152 ? 0.11740 0.12760 0.13390 0.00030  0.01180  -0.00060 1611 HIS A O   
2300 C  CB  . HIS A 152 ? 0.12370 0.11900 0.10970 -0.00650 0.00620  -0.00170 1611 HIS A CB  
2301 C  CG  . HIS A 152 ? 0.12920 0.11410 0.11570 0.00100  0.00490  -0.01450 1611 HIS A CG  
2302 N  ND1 . HIS A 152 ? 0.13660 0.11450 0.11910 0.00580  0.00330  -0.01280 1611 HIS A ND1 
2303 C  CD2 . HIS A 152 ? 0.13630 0.11330 0.10230 0.00680  -0.01160 -0.00250 1611 HIS A CD2 
2304 C  CE1 . HIS A 152 ? 0.14730 0.11730 0.10890 0.00570  0.01090  -0.00800 1611 HIS A CE1 
2305 N  NE2 . HIS A 152 ? 0.13600 0.11640 0.10170 0.00990  -0.00810 -0.00010 1611 HIS A NE2 
2313 N  N   . ILE A 153 ? 0.09910 0.11680 0.10450 -0.00540 -0.00450 0.00040  1612 ILE A N   
2314 C  CA  . ILE A 153 ? 0.10630 0.11910 0.10340 -0.00560 -0.00230 0.00070  1612 ILE A CA  
2315 C  C   . ILE A 153 ? 0.11660 0.12250 0.07790 -0.00400 -0.00550 0.00890  1612 ILE A C   
2316 O  O   . ILE A 153 ? 0.12420 0.12690 0.10090 -0.01300 -0.00880 0.00860  1612 ILE A O   
2317 C  CB  . ILE A 153 ? 0.11030 0.11760 0.09930 -0.00210 -0.01390 -0.00260 1612 ILE A CB  
2318 C  CG1 . ILE A 153 ? 0.12050 0.12120 0.12530 -0.00220 -0.02570 -0.00290 1612 ILE A CG1 
2319 C  CG2 . ILE A 153 ? 0.11660 0.11800 0.10350 -0.00050 -0.02280 0.00010  1612 ILE A CG2 
2320 C  CD1 . ILE A 153 ? 0.14410 0.12250 0.15490 -0.01310 -0.02200 -0.02120 1612 ILE A CD1 
2332 N  N   . CYS A 154 ? 0.11080 0.11510 0.10690 -0.00910 0.00120  -0.00120 1613 CYS A N   
2333 C  CA  . CYS A 154 ? 0.10140 0.10970 0.12260 -0.01040 0.00580  -0.00550 1613 CYS A CA  
2334 C  C   . CYS A 154 ? 0.10380 0.11010 0.11620 -0.00400 -0.00050 -0.01300 1613 CYS A C   
2335 O  O   . CYS A 154 ? 0.12320 0.10790 0.11440 0.00220  -0.01370 -0.01700 1613 CYS A O   
2336 C  CB  . CYS A 154 ? 0.10400 0.10790 0.14190 -0.00930 -0.00030 0.01530  1613 CYS A CB  
2337 S  SG  . CYS A 154 ? 0.12440 0.11260 0.15510 -0.01420 -0.01190 0.01080  1613 CYS A SG  
2342 N  N   . HIS A 155 ? 0.10470 0.11050 0.11420 0.00340  -0.00170 -0.01140 1614 HIS A N   
2343 C  CA  . HIS A 155 ? 0.11240 0.11340 0.11320 0.00900  -0.00680 -0.01420 1614 HIS A CA  
2344 C  C   . HIS A 155 ? 0.10160 0.11410 0.11190 0.01230  -0.00880 -0.01850 1614 HIS A C   
2345 O  O   . HIS A 155 ? 0.11350 0.11500 0.13800 0.00650  0.00590  -0.01020 1614 HIS A O   
2346 C  CB  . HIS A 155 ? 0.12270 0.11070 0.09420 0.00290  -0.00010 -0.02110 1614 HIS A CB  
2347 C  CG  . HIS A 155 ? 0.10780 0.11870 0.08120 0.01100  -0.01040 -0.00970 1614 HIS A CG  
2348 N  ND1 . HIS A 155 ? 0.10920 0.12060 0.09810 0.00980  0.00180  -0.02660 1614 HIS A ND1 
2349 C  CD2 . HIS A 155 ? 0.11980 0.12050 0.10220 -0.00370 0.00030  -0.01020 1614 HIS A CD2 
2350 C  CE1 . HIS A 155 ? 0.12130 0.12240 0.11580 0.00980  -0.01190 -0.02630 1614 HIS A CE1 
2351 N  NE2 . HIS A 155 ? 0.11890 0.12400 0.12020 0.00030  -0.01360 -0.02520 1614 HIS A NE2 
2359 N  N   . VAL A 156 ? 0.10800 0.11350 0.10170 0.00780  -0.00600 -0.00650 1615 VAL A N   
2360 C  CA  . VAL A 156 ? 0.11190 0.11600 0.09540 0.00560  -0.01590 -0.00700 1615 VAL A CA  
2361 C  C   . VAL A 156 ? 0.11380 0.11840 0.09330 0.00320  0.00240  -0.00230 1615 VAL A C   
2362 O  O   . VAL A 156 ? 0.12720 0.12350 0.12290 0.01100  -0.01010 -0.00710 1615 VAL A O   
2363 C  CB  . VAL A 156 ? 0.12460 0.11890 0.12700 0.00720  -0.00440 0.00150  1615 VAL A CB  
2364 C  CG1 . VAL A 156 ? 0.13300 0.12090 0.13980 0.00830  -0.00130 -0.00700 1615 VAL A CG1 
2365 C  CG2 . VAL A 156 ? 0.11630 0.12040 0.12540 0.00030  -0.02760 -0.00380 1615 VAL A CG2 
2375 N  N   . ALA A 157 ? 0.12100 0.11870 0.12160 -0.00490 -0.00570 -0.00850 1616 ALA A N   
2376 C  CA  . ALA A 157 ? 0.12740 0.12430 0.12470 0.00520  -0.01280 -0.01480 1616 ALA A CA  
2377 C  C   . ALA A 157 ? 0.12750 0.12810 0.13600 0.01540  -0.02400 -0.00770 1616 ALA A C   
2378 O  O   . ALA A 157 ? 0.14940 0.13280 0.14980 0.01800  -0.03050 -0.00330 1616 ALA A O   
2379 C  CB  . ALA A 157 ? 0.11880 0.12560 0.13930 0.00220  -0.00720 -0.00710 1616 ALA A CB  
2385 N  N   . ARG A 158 ? 0.11890 0.12920 0.12640 0.00600  -0.00730 0.00640  1617 ARG A N   
2386 C  CA  . ARG A 158 ? 0.13540 0.13160 0.12280 0.00300  0.00870  0.01240  1617 ARG A CA  
2387 C  C   . ARG A 158 ? 0.13120 0.12900 0.12490 0.00500  -0.00460 0.00880  1617 ARG A C   
2388 O  O   . ARG A 158 ? 0.12950 0.12690 0.13990 0.00770  -0.00850 0.00660  1617 ARG A O   
2389 C  CB  . ARG A 158 ? 0.14880 0.14350 0.13460 -0.00260 0.01850  0.00210  1617 ARG A CB  
2390 C  CG  . ARG A 158 ? 0.16280 0.16080 0.14910 0.00200  0.03430  -0.00900 1617 ARG A CG  
2391 C  CD  . ARG A 158 ? 0.17830 0.17800 0.16220 0.00290  0.03130  -0.01160 1617 ARG A CD  
2392 N  NE  . ARG A 158 ? 0.18570 0.18370 0.17380 0.00620  0.01830  -0.00310 1617 ARG A NE  
2393 C  CZ  . ARG A 158 ? 0.17530 0.18590 0.18290 -0.01210 0.01230  -0.00310 1617 ARG A CZ  
2394 N  NH1 . ARG A 158 ? 0.16680 0.18310 0.17620 -0.02350 -0.00310 0.01380  1617 ARG A NH1 
2395 N  NH2 . ARG A 158 ? 0.17860 0.18940 0.21390 -0.01340 0.01820  -0.00010 1617 ARG A NH2 
2409 N  N   . LYS A 159 ? 0.12710 0.13400 0.14230 0.00580  -0.00030 0.01080  1618 LYS A N   
2410 C  CA  . LYS A 159 ? 0.14390 0.13600 0.14980 0.00520  0.01090  0.01670  1618 LYS A CA  
2411 C  C   . LYS A 159 ? 0.14640 0.12150 0.14900 0.00870  0.00700  0.00790  1618 LYS A C   
2412 O  O   . LYS A 159 ? 0.14910 0.11900 0.15550 0.00760  0.00070  0.00660  1618 LYS A O   
2413 C  CB  . LYS A 159 ? 0.14790 0.15340 0.15720 0.00560  0.00460  0.02370  1618 LYS A CB  
2414 C  CG  . LYS A 159 ? 0.16590 0.16880 0.18150 0.00170  -0.00770 0.05010  1618 LYS A CG  
2415 C  CD  . LYS A 159 ? 0.20690 0.19130 0.23210 -0.01030 -0.01550 0.06180  1618 LYS A CD  
2416 C  CE  . LYS A 159 ? 0.27700 0.21560 0.30710 -0.01260 -0.00600 0.07600  1618 LYS A CE  
2417 N  NZ  . LYS A 159 ? 0.32010 0.22970 0.36090 -0.01400 -0.00010 0.08230  1618 LYS A NZ  
2431 N  N   . GLU A 160 ? 0.14610 0.12640 0.15120 0.01090  0.00250  -0.00540 1619 GLU A N   
2432 C  CA  . GLU A 160 ? 0.15220 0.12730 0.14400 0.02080  -0.00540 -0.00990 1619 GLU A CA  
2433 C  C   . GLU A 160 ? 0.14010 0.12210 0.15230 0.01110  -0.00810 -0.01140 1619 GLU A C   
2434 O  O   . GLU A 160 ? 0.15180 0.12190 0.16910 -0.00230 -0.01090 -0.00710 1619 GLU A O   
2435 C  CB  . GLU A 160 ? 0.19470 0.14190 0.16210 0.02200  -0.00750 -0.01640 1619 GLU A CB  
2436 C  CG  . GLU A 160 ? 0.20400 0.14880 0.18880 0.00340  -0.00350 -0.00570 1619 GLU A CG  
2437 C  CD  . GLU A 160 ? 0.19780 0.15380 0.19470 -0.00960 0.01150  -0.00830 1619 GLU A CD  
2438 O  OE1 . GLU A 160 ? 0.21450 0.16470 0.21330 -0.00090 0.00560  -0.00870 1619 GLU A OE1 
2439 O  OE2 . GLU A 160 ? 0.20850 0.15690 0.21480 -0.01230 0.01120  -0.01270 1619 GLU A OE2 
2446 N  N   . GLU A 161 ? 0.11300 0.12110 0.14190 0.00280  -0.00960 -0.00660 1620 GLU A N   
2447 C  CA  . GLU A 161 ? 0.12340 0.12540 0.12370 -0.00530 -0.00570 -0.00440 1620 GLU A CA  
2448 C  C   . GLU A 161 ? 0.12060 0.11430 0.11280 -0.00170 -0.00160 -0.01120 1620 GLU A C   
2449 O  O   . GLU A 161 ? 0.13270 0.11100 0.13190 -0.00170 -0.00490 0.00730  1620 GLU A O   
2450 C  CB  . GLU A 161 ? 0.13530 0.13410 0.12600 -0.00100 0.01960  0.00500  1620 GLU A CB  
2451 C  CG  . GLU A 161 ? 0.14000 0.14310 0.12730 -0.00160 0.02580  -0.00650 1620 GLU A CG  
2452 C  CD  . GLU A 161 ? 0.14480 0.14800 0.11070 -0.00030 0.01730  -0.01430 1620 GLU A CD  
2453 O  OE1 . GLU A 161 ? 0.15900 0.14800 0.12560 -0.00250 0.01220  -0.01640 1620 GLU A OE1 
2454 O  OE2 . GLU A 161 ? 0.15760 0.16130 0.13480 -0.00950 -0.00380 -0.00820 1620 GLU A OE2 
2461 N  N   . ILE A 162 ? 0.12790 0.11610 0.10850 -0.00160 0.00680  -0.00740 1621 ILE A N   
2462 C  CA  . ILE A 162 ? 0.12670 0.11660 0.11370 -0.00170 0.01620  -0.00380 1621 ILE A CA  
2463 C  C   . ILE A 162 ? 0.12670 0.11360 0.12890 -0.01000 0.01790  -0.00570 1621 ILE A C   
2464 O  O   . ILE A 162 ? 0.11870 0.11290 0.16380 -0.00990 0.01050  -0.00870 1621 ILE A O   
2465 C  CB  . ILE A 162 ? 0.13840 0.12780 0.12150 -0.00480 0.01540  -0.00610 1621 ILE A CB  
2466 C  CG1 . ILE A 162 ? 0.14250 0.12770 0.14680 -0.00120 0.01320  -0.02460 1621 ILE A CG1 
2467 C  CG2 . ILE A 162 ? 0.16340 0.13650 0.13040 -0.00930 0.00610  0.00090  1621 ILE A CG2 
2468 C  CD1 . ILE A 162 ? 0.15850 0.13480 0.19250 0.01140  0.02170  -0.02370 1621 ILE A CD1 
2480 N  N   . LEU A 163 ? 0.13730 0.11470 0.13710 -0.02000 0.00030  -0.00960 1622 LEU A N   
2481 C  CA  . LEU A 163 ? 0.13850 0.11490 0.13960 -0.01220 0.01320  0.00590  1622 LEU A CA  
2482 C  C   . LEU A 163 ? 0.13450 0.11600 0.14990 -0.00730 0.01450  0.00220  1622 LEU A C   
2483 O  O   . LEU A 163 ? 0.13660 0.11540 0.16580 -0.00930 0.02160  0.01280  1622 LEU A O   
2484 C  CB  . LEU A 163 ? 0.15630 0.12390 0.14430 -0.00390 0.01390  0.00570  1622 LEU A CB  
2485 C  CG  . LEU A 163 ? 0.17420 0.13180 0.14310 -0.00370 0.01870  0.01940  1622 LEU A CG  
2486 C  CD1 . LEU A 163 ? 0.18910 0.14110 0.17990 0.00560  0.00640  0.01850  1622 LEU A CD1 
2487 C  CD2 . LEU A 163 ? 0.19220 0.13190 0.14050 0.00100  0.01980  0.02060  1622 LEU A CD2 
2499 N  N   A LEU A 164 ? 0.14240 0.12710 0.14590 -0.00300 0.00650  -0.01130 1623 LEU A N   
2500 N  N   B LEU A 164 ? 0.14240 0.12710 0.14590 -0.00300 0.00650  -0.01130 1623 LEU A N   
2501 C  CA  A LEU A 164 ? 0.13430 0.14010 0.14400 -0.00480 0.01420  -0.01140 1623 LEU A CA  
2502 C  CA  B LEU A 164 ? 0.13430 0.14010 0.14400 -0.00480 0.01420  -0.01140 1623 LEU A CA  
2503 C  C   A LEU A 164 ? 0.12020 0.13450 0.14140 -0.00290 -0.01020 -0.01610 1623 LEU A C   
2504 C  C   B LEU A 164 ? 0.12020 0.13450 0.14140 -0.00290 -0.01020 -0.01610 1623 LEU A C   
2505 O  O   A LEU A 164 ? 0.12680 0.13700 0.14880 -0.00680 0.01060  -0.02160 1623 LEU A O   
2506 O  O   B LEU A 164 ? 0.12680 0.13700 0.14880 -0.00680 0.01060  -0.02160 1623 LEU A O   
2507 C  CB  A LEU A 164 ? 0.14770 0.16730 0.17370 -0.01010 0.03610  -0.01980 1623 LEU A CB  
2508 C  CB  B LEU A 164 ? 0.14770 0.16730 0.17370 -0.01010 0.03610  -0.01980 1623 LEU A CB  
2509 C  CG  A LEU A 164 ? 0.20030 0.19870 0.22760 -0.01310 0.04010  -0.00960 1623 LEU A CG  
2510 C  CG  B LEU A 164 ? 0.20030 0.19870 0.22760 -0.01300 0.04020  -0.00970 1623 LEU A CG  
2511 C  CD1 A LEU A 164 ? 0.22590 0.20760 0.27920 -0.01410 0.06040  -0.01270 1623 LEU A CD1 
2512 C  CD1 B LEU A 164 ? 0.22600 0.20790 0.27910 -0.01420 0.06030  -0.01270 1623 LEU A CD1 
2513 C  CD2 A LEU A 164 ? 0.22390 0.21030 0.23470 -0.01850 0.01000  -0.02270 1623 LEU A CD2 
2514 C  CD2 B LEU A 164 ? 0.22390 0.21010 0.23470 -0.01860 0.01000  -0.02250 1623 LEU A CD2 
2537 N  N   . ILE A 165 ? 0.11040 0.12760 0.13420 -0.00400 0.00050  -0.01090 1624 ILE A N   
2538 C  CA  . ILE A 165 ? 0.12460 0.12220 0.12980 -0.00640 0.00570  -0.00140 1624 ILE A CA  
2539 C  C   . ILE A 165 ? 0.12170 0.12180 0.13570 -0.01590 0.01130  -0.01120 1624 ILE A C   
2540 O  O   . ILE A 165 ? 0.11920 0.11910 0.17140 -0.01470 0.02010  -0.01550 1624 ILE A O   
2541 C  CB  . ILE A 165 ? 0.13490 0.12500 0.13110 -0.00480 0.00040  0.00430  1624 ILE A CB  
2542 C  CG1 . ILE A 165 ? 0.13380 0.13020 0.12770 -0.00210 -0.00670 0.00660  1624 ILE A CG1 
2543 C  CG2 . ILE A 165 ? 0.13590 0.13100 0.14700 -0.00650 0.00070  -0.00180 1624 ILE A CG2 
2544 C  CD1 . ILE A 165 ? 0.13770 0.13560 0.13490 -0.00890 -0.00480 0.01450  1624 ILE A CD1 
2556 N  N   A LYS A 166 ? 0.11980 0.12440 0.12970 -0.02040 0.01960  -0.01000 1625 LYS A N   
2557 N  N   B LYS A 166 ? 0.12280 0.12590 0.13050 -0.01860 0.01720  -0.01120 1625 LYS A N   
2558 C  CA  A LYS A 166 ? 0.12930 0.13100 0.13690 -0.01060 0.01270  -0.01860 1625 LYS A CA  
2559 C  CA  B LYS A 166 ? 0.13310 0.13290 0.13700 -0.01030 0.01060  -0.01860 1625 LYS A CA  
2560 C  C   A LYS A 166 ? 0.12680 0.12800 0.14750 -0.00730 0.01480  -0.02870 1625 LYS A C   
2561 C  C   B LYS A 166 ? 0.12910 0.12960 0.14540 -0.00780 0.01260  -0.02760 1625 LYS A C   
2562 O  O   A LYS A 166 ? 0.12280 0.12810 0.17070 -0.00090 0.00150  -0.02590 1625 LYS A O   
2563 O  O   B LYS A 166 ? 0.12550 0.13000 0.16450 -0.00290 0.00200  -0.02540 1625 LYS A O   
2564 C  CB  A LYS A 166 ? 0.15390 0.14310 0.14560 -0.01590 0.00800  -0.01930 1625 LYS A CB  
2565 C  CB  B LYS A 166 ? 0.15790 0.14400 0.14650 -0.01400 0.00540  -0.01850 1625 LYS A CB  
2566 C  CG  A LYS A 166 ? 0.17510 0.15420 0.16810 -0.01860 0.00630  -0.01440 1625 LYS A CG  
2567 C  CG  B LYS A 166 ? 0.18250 0.15400 0.16840 -0.01790 0.00250  -0.01360 1625 LYS A CG  
2568 C  CD  A LYS A 166 ? 0.21510 0.16710 0.19630 -0.01740 0.00300  -0.00880 1625 LYS A CD  
2569 C  CD  B LYS A 166 ? 0.21750 0.16430 0.19810 -0.02280 -0.00180 -0.00630 1625 LYS A CD  
2570 C  CE  A LYS A 166 ? 0.24910 0.17510 0.22220 -0.00530 0.00750  -0.00970 1625 LYS A CE  
2571 C  CE  B LYS A 166 ? 0.23740 0.16930 0.22400 -0.02510 -0.00820 -0.00140 1625 LYS A CE  
2572 N  NZ  A LYS A 166 ? 0.27220 0.17960 0.25270 0.00100  0.01140  -0.01670 1625 LYS A NZ  
2573 N  NZ  B LYS A 166 ? 0.24530 0.17080 0.24190 -0.02980 -0.01880 -0.00480 1625 LYS A NZ  
2600 N  N   . ALA A 167 ? 0.13140 0.12710 0.14130 -0.00840 0.00440  -0.03050 1626 ALA A N   
2601 C  CA  . ALA A 167 ? 0.13910 0.12410 0.14760 -0.01180 0.01360  -0.02830 1626 ALA A CA  
2602 C  C   . ALA A 167 ? 0.13320 0.11270 0.15710 -0.01860 0.00410  -0.01280 1626 ALA A C   
2603 O  O   . ALA A 167 ? 0.14500 0.11100 0.18110 -0.01930 0.00870  -0.00930 1626 ALA A O   
2604 C  CB  . ALA A 167 ? 0.14790 0.13180 0.16190 -0.00400 0.01480  -0.02700 1626 ALA A CB  
2610 N  N   . ALA A 168 ? 0.13510 0.11880 0.14930 -0.02240 -0.00250 -0.01080 1627 ALA A N   
2611 C  CA  . ALA A 168 ? 0.13750 0.12030 0.14910 -0.00840 0.00710  -0.00660 1627 ALA A CA  
2612 C  C   . ALA A 168 ? 0.12850 0.12420 0.14760 -0.01330 0.00170  -0.01210 1627 ALA A C   
2613 O  O   . ALA A 168 ? 0.13220 0.12410 0.16920 -0.01400 -0.01340 -0.00680 1627 ALA A O   
2614 C  CB  . ALA A 168 ? 0.14380 0.11720 0.15430 -0.00800 0.00770  -0.00610 1627 ALA A CB  
2620 N  N   . LYS A 169 ? 0.11980 0.13200 0.14050 -0.00920 0.00350  -0.01850 1628 LYS A N   
2621 C  CA  . LYS A 169 ? 0.12130 0.14190 0.16920 0.00070  0.00750  -0.01980 1628 LYS A CA  
2622 C  C   . LYS A 169 ? 0.13240 0.15280 0.19260 -0.00670 0.00950  -0.02280 1628 LYS A C   
2623 O  O   . LYS A 169 ? 0.12490 0.15880 0.21240 -0.00490 0.01210  -0.03280 1628 LYS A O   
2624 C  CB  . LYS A 169 ? 0.11840 0.14150 0.16900 0.00020  0.00870  -0.01300 1628 LYS A CB  
2625 C  CG  . LYS A 169 ? 0.11260 0.14110 0.14840 -0.00680 0.00870  -0.01090 1628 LYS A CG  
2626 C  CD  . LYS A 169 ? 0.12720 0.14420 0.13920 -0.01180 0.00000  -0.00640 1628 LYS A CD  
2627 C  CE  . LYS A 169 ? 0.13400 0.13740 0.13250 -0.01530 -0.00310 -0.00330 1628 LYS A CE  
2628 N  NZ  . LYS A 169 ? 0.13380 0.13890 0.13660 -0.02420 0.02280  -0.00250 1628 LYS A NZ  
2642 N  N   . ALA A 170 ? 0.12980 0.15430 0.19930 -0.02290 0.03100  -0.02670 1629 ALA A N   
2643 C  CA  . ALA A 170 ? 0.12620 0.16570 0.20200 -0.02970 0.02750  -0.02510 1629 ALA A CA  
2644 C  C   . ALA A 170 ? 0.13570 0.17490 0.20970 -0.03570 0.01390  -0.02600 1629 ALA A C   
2645 O  O   . ALA A 170 ? 0.15170 0.19030 0.23210 -0.05100 0.01120  -0.02760 1629 ALA A O   
2646 C  CB  . ALA A 170 ? 0.14220 0.16580 0.21450 -0.03220 0.03190  -0.02920 1629 ALA A CB  
2652 N  N   . ARG A 171 ? 0.14860 0.16970 0.18460 -0.03110 0.01530  -0.02950 1630 ARG A N   
2653 C  CA  . ARG A 171 ? 0.15160 0.18140 0.17880 -0.03310 0.01490  -0.01910 1630 ARG A CA  
2654 C  C   . ARG A 171 ? 0.13890 0.17470 0.18530 -0.03180 -0.01370 -0.02050 1630 ARG A C   
2655 O  O   . ARG A 171 ? 0.17560 0.17780 0.21800 -0.02220 -0.01630 -0.01430 1630 ARG A O   
2656 C  CB  . ARG A 171 ? 0.18540 0.20080 0.20080 -0.03320 0.00560  -0.01900 1630 ARG A CB  
2657 C  CG  . ARG A 171 ? 0.22370 0.22360 0.21310 -0.02250 -0.00960 -0.02090 1630 ARG A CG  
2658 C  CD  . ARG A 171 ? 0.26840 0.24950 0.25160 -0.01980 -0.01670 -0.01750 1630 ARG A CD  
2659 N  NE  . ARG A 171 ? 0.30320 0.27020 0.28090 -0.01960 -0.03590 -0.02440 1630 ARG A NE  
2660 C  CZ  . ARG A 171 ? 0.32800 0.28770 0.29580 -0.02350 -0.01450 -0.02350 1630 ARG A CZ  
2661 N  NH1 . ARG A 171 ? 0.33060 0.29490 0.32750 -0.03480 0.01270  -0.02330 1630 ARG A NH1 
2662 N  NH2 . ARG A 171 ? 0.34480 0.29320 0.28290 -0.01790 -0.02830 -0.02520 1630 ARG A NH2 
2676 N  N   . GLY A 172 ? 0.11310 0.17240 0.19600 -0.01920 0.00030  -0.01850 1631 GLY A N   
2677 C  CA  . GLY A 172 ? 0.13050 0.17390 0.21340 -0.00680 -0.00860 -0.00410 1631 GLY A CA  
2678 C  C   . GLY A 172 ? 0.13430 0.17060 0.20750 0.00470  -0.01430 0.00260  1631 GLY A C   
2679 O  O   . GLY A 172 ? 0.14640 0.18330 0.22590 0.00770  -0.01010 0.00680  1631 GLY A O   
2683 N  N   . LEU A 173 ? 0.12400 0.15590 0.18920 0.00390  -0.00770 0.00180  1632 LEU A N   
2684 C  CA  . LEU A 173 ? 0.14010 0.15130 0.17050 0.00690  -0.01350 -0.00440 1632 LEU A CA  
2685 C  C   . LEU A 173 ? 0.11220 0.14070 0.15760 0.00160  -0.02050 -0.00690 1632 LEU A C   
2686 O  O   . LEU A 173 ? 0.12840 0.14290 0.16970 -0.00330 0.00080  -0.01150 1632 LEU A O   
2687 C  CB  . LEU A 173 ? 0.17130 0.15450 0.17980 0.01070  -0.01590 -0.00820 1632 LEU A CB  
2688 C  CG  . LEU A 173 ? 0.21880 0.16470 0.18840 0.02300  -0.03530 -0.02740 1632 LEU A CG  
2689 C  CD1 . LEU A 173 ? 0.23790 0.16900 0.18250 0.02870  -0.03170 -0.03190 1632 LEU A CD1 
2690 C  CD2 . LEU A 173 ? 0.24790 0.17020 0.21550 0.02140  -0.03710 -0.02720 1632 LEU A CD2 
2702 N  N   . PRO A 174 ? 0.10700 0.13130 0.15310 -0.00310 -0.01310 -0.01410 1633 PRO A N   
2703 C  CA  . PRO A 174 ? 0.11140 0.12700 0.12950 -0.00660 -0.01640 -0.01010 1633 PRO A CA  
2704 C  C   . PRO A 174 ? 0.12320 0.13310 0.12820 -0.00680 -0.00080 -0.00180 1633 PRO A C   
2705 O  O   . PRO A 174 ? 0.13130 0.14170 0.14090 -0.00420 -0.01400 0.00530  1633 PRO A O   
2706 C  CB  . PRO A 174 ? 0.11090 0.13600 0.14040 -0.01010 -0.01430 -0.01320 1633 PRO A CB  
2707 C  CG  . PRO A 174 ? 0.12050 0.14120 0.15790 -0.01090 -0.02550 -0.01520 1633 PRO A CG  
2708 C  CD  . PRO A 174 ? 0.12040 0.14080 0.17420 -0.00580 -0.02480 -0.01390 1633 PRO A CD  
2716 N  N   . VAL A 175 ? 0.11450 0.12760 0.13290 -0.00240 0.01020  -0.00370 1634 VAL A N   
2717 C  CA  . VAL A 175 ? 0.11140 0.12420 0.12600 0.00160  0.01110  -0.00940 1634 VAL A CA  
2718 C  C   . VAL A 175 ? 0.10580 0.12230 0.11190 -0.00640 0.01230  -0.00370 1634 VAL A C   
2719 O  O   . VAL A 175 ? 0.12780 0.12500 0.14320 -0.02170 0.01490  -0.01530 1634 VAL A O   
2720 C  CB  . VAL A 175 ? 0.11780 0.12380 0.13920 0.00270  0.01180  -0.00470 1634 VAL A CB  
2721 C  CG1 . VAL A 175 ? 0.13060 0.12320 0.15150 -0.00050 0.00570  -0.00510 1634 VAL A CG1 
2722 C  CG2 . VAL A 175 ? 0.12620 0.12750 0.14330 -0.00200 -0.01020 -0.01290 1634 VAL A CG2 
2732 N  N   . THR A 176 ? 0.11050 0.12110 0.11120 -0.00170 -0.00160 0.00160  1635 THR A N   
2733 C  CA  . THR A 176 ? 0.12450 0.11170 0.11610 -0.00320 0.00130  -0.01470 1635 THR A CA  
2734 C  C   . THR A 176 ? 0.11640 0.10790 0.11040 -0.00160 -0.00240 -0.01620 1635 THR A C   
2735 O  O   . THR A 176 ? 0.11710 0.10610 0.12330 -0.00410 -0.00020 -0.01220 1635 THR A O   
2736 C  CB  . THR A 176 ? 0.12750 0.11420 0.14160 0.00790  -0.00540 -0.00410 1635 THR A CB  
2737 O  OG1 . THR A 176 ? 0.14020 0.11430 0.15560 0.01110  -0.00600 0.00630  1635 THR A OG1 
2738 C  CG2 . THR A 176 ? 0.12090 0.11660 0.16380 0.01720  -0.01510 -0.01710 1635 THR A CG2 
2746 N  N   . CYS A 177 ? 0.10180 0.11280 0.12530 0.00240  -0.00120 -0.01740 1636 CYS A N   
2747 C  CA  . CYS A 177 ? 0.11060 0.11000 0.11750 -0.00070 -0.00270 -0.01200 1636 CYS A CA  
2748 C  C   . CYS A 177 ? 0.11100 0.11620 0.09790 0.00270  0.00160  -0.00520 1636 CYS A C   
2749 O  O   . CYS A 177 ? 0.11060 0.12210 0.10730 -0.00190 0.01110  -0.00790 1636 CYS A O   
2750 C  CB  . CYS A 177 ? 0.11640 0.10740 0.13600 -0.00500 0.01110  -0.01020 1636 CYS A CB  
2751 S  SG  . CYS A 177 ? 0.14540 0.11310 0.13800 -0.00450 0.01520  -0.00120 1636 CYS A SG  
2757 N  N   . GLU A 178 ? 0.10180 0.11430 0.10340 0.00080  0.00360  -0.01090 1637 GLU A N   
2758 C  CA  . GLU A 178 ? 0.11120 0.11690 0.11190 -0.00580 -0.00500 -0.01020 1637 GLU A CA  
2759 C  C   . GLU A 178 ? 0.10160 0.11330 0.10420 0.00140  -0.00730 -0.01640 1637 GLU A C   
2760 O  O   . GLU A 178 ? 0.11350 0.11520 0.13500 0.01070  -0.00220 -0.01640 1637 GLU A O   
2761 C  CB  . GLU A 178 ? 0.13200 0.11990 0.11800 -0.00140 0.00240  -0.01470 1637 GLU A CB  
2762 C  CG  . GLU A 178 ? 0.14030 0.12290 0.10910 -0.00930 0.01170  -0.02000 1637 GLU A CG  
2763 C  CD  . GLU A 178 ? 0.15260 0.12070 0.11500 -0.01680 0.01050  -0.01840 1637 GLU A CD  
2764 O  OE1 . GLU A 178 ? 0.15590 0.12270 0.12860 -0.01820 -0.01710 0.00420  1637 GLU A OE1 
2765 O  OE2 . GLU A 178 ? 0.15930 0.12060 0.13180 -0.02410 0.03370  -0.02570 1637 GLU A OE2 
2772 N  N   . VAL A 179 ? 0.09950 0.11160 0.11370 0.00420  -0.01060 -0.00820 1638 VAL A N   
2773 C  CA  . VAL A 179 ? 0.09720 0.11560 0.10660 0.00170  -0.00850 -0.00790 1638 VAL A CA  
2774 C  C   . VAL A 179 ? 0.09740 0.12070 0.12210 0.01150  0.00380  -0.01630 1638 VAL A C   
2775 O  O   . VAL A 179 ? 0.09820 0.11720 0.15960 0.01550  0.00850  -0.01860 1638 VAL A O   
2776 C  CB  . VAL A 179 ? 0.11430 0.12270 0.11080 -0.00160 0.00150  -0.00680 1638 VAL A CB  
2777 C  CG1 . VAL A 179 ? 0.13670 0.13220 0.12450 -0.00280 -0.02350 0.00150  1638 VAL A CG1 
2778 C  CG2 . VAL A 179 ? 0.11690 0.12340 0.10920 0.00120  0.00740  -0.02110 1638 VAL A CG2 
2788 N  N   . ALA A 180 ? 0.10490 0.12470 0.11630 0.01540  -0.01000 -0.01050 1639 ALA A N   
2789 C  CA  . ALA A 180 ? 0.10860 0.12640 0.11890 0.00590  -0.00630 -0.01400 1639 ALA A CA  
2790 C  C   . ALA A 180 ? 0.11250 0.12630 0.12600 0.00970  -0.01370 -0.01340 1639 ALA A C   
2791 O  O   . ALA A 180 ? 0.11500 0.12570 0.13790 0.00080  -0.00920 0.01360  1639 ALA A O   
2792 C  CB  . ALA A 180 ? 0.11950 0.12200 0.11670 -0.00520 0.00600  -0.01070 1639 ALA A CB  
2798 N  N   . PRO A 181 ? 0.12700 0.12930 0.12870 0.00370  -0.01170 -0.02810 1640 PRO A N   
2799 C  CA  . PRO A 181 ? 0.12920 0.13560 0.11740 0.00590  -0.00360 -0.02510 1640 PRO A CA  
2800 C  C   . PRO A 181 ? 0.13310 0.14180 0.10900 -0.00010 -0.00630 -0.01220 1640 PRO A C   
2801 O  O   . PRO A 181 ? 0.14050 0.14920 0.09900 0.00360  0.00760  -0.00230 1640 PRO A O   
2802 C  CB  . PRO A 181 ? 0.15360 0.13930 0.14770 0.00610  -0.01400 -0.02550 1640 PRO A CB  
2803 C  CG  . PRO A 181 ? 0.18820 0.13890 0.16700 -0.00150 -0.03710 -0.02350 1640 PRO A CG  
2804 C  CD  . PRO A 181 ? 0.15110 0.13170 0.14080 -0.00420 -0.01750 -0.02660 1640 PRO A CD  
2812 N  N   . HIS A 182 ? 0.11650 0.14210 0.12630 0.00150  -0.00710 -0.01030 1641 HIS A N   
2813 C  CA  . HIS A 182 ? 0.11970 0.14240 0.14530 0.01240  -0.00460 -0.00330 1641 HIS A CA  
2814 C  C   . HIS A 182 ? 0.12030 0.14280 0.14050 0.01380  -0.01210 0.00140  1641 HIS A C   
2815 O  O   . HIS A 182 ? 0.13210 0.14800 0.14720 0.01090  -0.03240 -0.00110 1641 HIS A O   
2816 C  CB  . HIS A 182 ? 0.11710 0.14380 0.13060 0.01310  -0.00390 0.00880  1641 HIS A CB  
2817 C  CG  . HIS A 182 ? 0.10720 0.14700 0.12000 0.00660  -0.00400 0.01160  1641 HIS A CG  
2818 N  ND1 . HIS A 182 ? 0.11500 0.14740 0.12130 -0.00170 -0.01950 0.00830  1641 HIS A ND1 
2819 C  CD2 . HIS A 182 ? 0.10720 0.14710 0.12460 0.00860  -0.01360 0.00750  1641 HIS A CD2 
2820 C  CE1 . HIS A 182 ? 0.11140 0.14390 0.10130 -0.00030 -0.00040 -0.00020 1641 HIS A CE1 
2821 N  NE2 . HIS A 182 ? 0.10720 0.14930 0.12760 0.00630  0.00280  -0.00120 1641 HIS A NE2 
2829 N  N   . HIS A 183 ? 0.11530 0.13940 0.11800 0.01240  -0.01640 0.00200  1642 HIS A N   
2830 C  CA  . HIS A 183 ? 0.12270 0.13870 0.10520 0.00960  -0.01440 0.00280  1642 HIS A CA  
2831 C  C   . HIS A 183 ? 0.12390 0.14170 0.11250 0.01510  -0.00360 -0.00250 1642 HIS A C   
2832 O  O   . HIS A 183 ? 0.14420 0.14120 0.14060 0.02060  0.01380  0.01340  1642 HIS A O   
2833 C  CB  . HIS A 183 ? 0.12420 0.13500 0.08930 0.00600  -0.01220 0.00220  1642 HIS A CB  
2834 C  CG  . HIS A 183 ? 0.11270 0.14320 0.09360 0.00950  -0.01140 -0.00720 1642 HIS A CG  
2835 N  ND1 . HIS A 183 ? 0.11670 0.14830 0.09790 0.00750  -0.00970 0.00200  1642 HIS A ND1 
2836 C  CD2 . HIS A 183 ? 0.12710 0.14990 0.11680 0.00730  -0.01250 -0.01630 1642 HIS A CD2 
2837 C  CE1 . HIS A 183 ? 0.12060 0.15130 0.11970 0.01110  -0.00460 -0.01470 1642 HIS A CE1 
2838 N  NE2 . HIS A 183 ? 0.12670 0.15220 0.11530 0.01440  -0.00220 -0.01550 1642 HIS A NE2 
2846 N  N   . LEU A 184 ? 0.12780 0.14210 0.10140 0.01360  -0.00800 -0.00050 1643 LEU A N   
2847 C  CA  . LEU A 184 ? 0.11950 0.15500 0.11480 0.01280  -0.00590 -0.00250 1643 LEU A CA  
2848 C  C   . LEU A 184 ? 0.13770 0.17120 0.12800 0.00690  -0.00030 0.00050  1643 LEU A C   
2849 O  O   . LEU A 184 ? 0.13790 0.18140 0.13770 0.00290  0.00320  0.00110  1643 LEU A O   
2850 C  CB  . LEU A 184 ? 0.12030 0.15690 0.12420 0.01340  -0.01710 0.00390  1643 LEU A CB  
2851 C  CG  . LEU A 184 ? 0.13470 0.16460 0.13470 0.01760  -0.00570 0.00820  1643 LEU A CG  
2852 C  CD1 . LEU A 184 ? 0.14560 0.16770 0.16320 0.02870  -0.01230 0.01120  1643 LEU A CD1 
2853 C  CD2 . LEU A 184 ? 0.14210 0.16860 0.14940 0.01120  0.00460  0.00960  1643 LEU A CD2 
2865 N  N   . PHE A 185 ? 0.13280 0.17780 0.12680 0.00380  -0.01680 -0.00250 1644 PHE A N   
2866 C  CA  . PHE A 185 ? 0.12780 0.17670 0.13220 0.00690  -0.02530 -0.00550 1644 PHE A CA  
2867 C  C   . PHE A 185 ? 0.13800 0.18640 0.13580 0.00550  -0.03750 -0.01070 1644 PHE A C   
2868 O  O   . PHE A 185 ? 0.15490 0.19440 0.15960 0.00060  -0.03580 -0.00550 1644 PHE A O   
2869 C  CB  . PHE A 185 ? 0.15100 0.16970 0.14460 0.01030  -0.00170 0.00220  1644 PHE A CB  
2870 C  CG  . PHE A 185 ? 0.15910 0.16790 0.14220 0.00810  0.00360  -0.00280 1644 PHE A CG  
2871 C  CD1 . PHE A 185 ? 0.17610 0.17530 0.14500 0.02490  0.01200  -0.00840 1644 PHE A CD1 
2872 C  CD2 . PHE A 185 ? 0.14430 0.16080 0.14710 0.00240  0.00350  -0.01550 1644 PHE A CD2 
2873 C  CE1 . PHE A 185 ? 0.18350 0.17960 0.14430 0.01600  0.02090  -0.01060 1644 PHE A CE1 
2874 C  CE2 . PHE A 185 ? 0.14940 0.16030 0.15940 0.00810  0.00210  -0.02670 1644 PHE A CE2 
2875 C  CZ  . PHE A 185 ? 0.15500 0.16540 0.14750 0.01530  0.01670  -0.02580 1644 PHE A CZ  
2885 N  N   . LEU A 186 ? 0.12420 0.18910 0.13600 0.01500  -0.03290 -0.01410 1645 LEU A N   
2886 C  CA  . LEU A 186 ? 0.12480 0.18850 0.13400 0.02370  -0.01920 -0.00550 1645 LEU A CA  
2887 C  C   . LEU A 186 ? 0.12630 0.18750 0.14310 0.02700  -0.03520 -0.00230 1645 LEU A C   
2888 O  O   . LEU A 186 ? 0.13120 0.18190 0.15250 0.01870  -0.03760 -0.00390 1645 LEU A O   
2889 C  CB  . LEU A 186 ? 0.12340 0.18750 0.14630 0.02040  -0.01800 -0.00770 1645 LEU A CB  
2890 C  CG  . LEU A 186 ? 0.12130 0.18810 0.13990 0.02290  -0.01540 -0.01430 1645 LEU A CG  
2891 C  CD1 . LEU A 186 ? 0.12960 0.19220 0.14930 0.00550  -0.01300 -0.01370 1645 LEU A CD1 
2892 C  CD2 . LEU A 186 ? 0.14690 0.18870 0.15660 0.02970  -0.01390 -0.01150 1645 LEU A CD2 
2904 N  N   . SER A 187 ? 0.14020 0.19570 0.15380 0.02640  -0.02800 -0.00610 1646 SER A N   
2905 C  CA  . SER A 187 ? 0.14480 0.19930 0.16860 0.02610  -0.02140 -0.00900 1646 SER A CA  
2906 C  C   . SER A 187 ? 0.14470 0.19680 0.19070 0.02800  -0.02380 -0.00770 1646 SER A C   
2907 O  O   . SER A 187 ? 0.13950 0.19260 0.20880 0.02860  -0.01870 -0.00500 1646 SER A O   
2908 C  CB  . SER A 187 ? 0.15130 0.20990 0.17950 0.02590  -0.02410 0.00010  1646 SER A CB  
2909 O  OG  . SER A 187 ? 0.16760 0.21310 0.20720 0.02970  -0.02880 0.00740  1646 SER A OG  
2915 N  N   . HIS A 188 ? 0.14150 0.19750 0.21300 0.02840  -0.02660 -0.00120 1647 HIS A N   
2916 C  CA  . HIS A 188 ? 0.16910 0.20570 0.23870 0.03790  -0.02740 -0.00050 1647 HIS A CA  
2917 C  C   . HIS A 188 ? 0.17520 0.21950 0.26170 0.04410  -0.04280 0.00550  1647 HIS A C   
2918 O  O   . HIS A 188 ? 0.17090 0.21850 0.30560 0.05530  -0.05360 -0.00520 1647 HIS A O   
2919 C  CB  . HIS A 188 ? 0.18520 0.20380 0.24460 0.04520  -0.00650 -0.00900 1647 HIS A CB  
2920 C  CG  . HIS A 188 ? 0.20650 0.20530 0.24570 0.05230  -0.00110 -0.01670 1647 HIS A CG  
2921 N  ND1 . HIS A 188 ? 0.20420 0.20430 0.24110 0.05390  -0.00610 -0.02680 1647 HIS A ND1 
2922 C  CD2 . HIS A 188 ? 0.22170 0.20640 0.24660 0.05400  -0.00100 -0.01900 1647 HIS A CD2 
2923 C  CE1 . HIS A 188 ? 0.21210 0.20660 0.25360 0.04900  0.00230  -0.02770 1647 HIS A CE1 
2924 N  NE2 . HIS A 188 ? 0.22010 0.20760 0.26130 0.05240  -0.00010 -0.02620 1647 HIS A NE2 
2932 N  N   . ASP A 189 ? 0.19000 0.24140 0.24640 0.04290  -0.06050 0.01990  1648 ASP A N   
2933 C  CA  . ASP A 189 ? 0.21030 0.26460 0.25050 0.04460  -0.07370 0.02860  1648 ASP A CA  
2934 C  C   . ASP A 189 ? 0.18190 0.26330 0.22970 0.04430  -0.06940 0.01750  1648 ASP A C   
2935 O  O   . ASP A 189 ? 0.19880 0.26630 0.24820 0.04120  -0.06710 0.02260  1648 ASP A O   
2936 C  CB  . ASP A 189 ? 0.27190 0.28920 0.27770 0.03710  -0.06230 0.03800  1648 ASP A CB  
2937 C  CG  . ASP A 189 ? 0.34110 0.31360 0.32490 0.02530  -0.02420 0.04650  1648 ASP A CG  
2938 O  OD1 . ASP A 189 ? 0.37380 0.34210 0.35060 0.01180  -0.01540 0.04660  1648 ASP A OD1 
2939 O  OD2 . ASP A 189 ? 0.37060 0.30370 0.35360 0.02530  -0.01460 0.05050  1648 ASP A OD2 
2944 N  N   . ASP A 190 ? 0.16720 0.25800 0.20220 0.04160  -0.06920 -0.00170 1649 ASP A N   
2945 C  CA  . ASP A 190 ? 0.16470 0.25610 0.20220 0.04800  -0.05790 -0.01330 1649 ASP A CA  
2946 C  C   . ASP A 190 ? 0.15140 0.24430 0.19270 0.03620  -0.04850 -0.00970 1649 ASP A C   
2947 O  O   . ASP A 190 ? 0.15460 0.23440 0.20980 0.02480  -0.04160 0.00080  1649 ASP A O   
2948 C  CB  . ASP A 190 ? 0.16820 0.26710 0.19870 0.05280  -0.05650 -0.03760 1649 ASP A CB  
2949 C  CG  . ASP A 190 ? 0.18840 0.28770 0.21790 0.04490  -0.05790 -0.05280 1649 ASP A CG  
2950 O  OD1 . ASP A 190 ? 0.21710 0.30900 0.26620 0.02750  -0.06190 -0.05720 1649 ASP A OD1 
2951 O  OD2 . ASP A 190 ? 0.16860 0.28560 0.20690 0.06060  -0.04560 -0.05360 1649 ASP A OD2 
2956 N  N   . LEU A 191 ? 0.15740 0.24650 0.19430 0.03750  -0.04070 -0.00840 1650 LEU A N   
2957 C  CA  . LEU A 191 ? 0.15750 0.25540 0.19370 0.03640  -0.02020 -0.01860 1650 LEU A CA  
2958 C  C   . LEU A 191 ? 0.15600 0.26910 0.22380 0.04090  -0.02010 -0.01080 1650 LEU A C   
2959 O  O   . LEU A 191 ? 0.17480 0.27030 0.23050 0.03560  -0.01520 -0.00610 1650 LEU A O   
2960 C  CB  . LEU A 191 ? 0.18140 0.25760 0.18740 0.03440  -0.01650 -0.02470 1650 LEU A CB  
2961 C  CG  . LEU A 191 ? 0.21260 0.26650 0.22120 0.03370  -0.01620 -0.02010 1650 LEU A CG  
2962 C  CD1 . LEU A 191 ? 0.21950 0.27020 0.23770 0.03610  -0.02790 -0.02390 1650 LEU A CD1 
2963 C  CD2 . LEU A 191 ? 0.23330 0.27110 0.22670 0.02730  -0.00280 -0.01760 1650 LEU A CD2 
2975 N  N   . GLU A 192 ? 0.15480 0.28790 0.25530 0.04630  -0.03080 -0.00780 1651 GLU A N   
2976 C  CA  . GLU A 192 ? 0.18150 0.30650 0.27430 0.04620  -0.04880 -0.00360 1651 GLU A CA  
2977 C  C   . GLU A 192 ? 0.16470 0.29510 0.24320 0.03120  -0.04020 -0.01010 1651 GLU A C   
2978 O  O   . GLU A 192 ? 0.16160 0.29600 0.25840 0.01660  -0.02260 -0.01380 1651 GLU A O   
2979 C  CB  . GLU A 192 ? 0.24540 0.33850 0.32990 0.04940  -0.07120 0.00560  1651 GLU A CB  
2980 C  CG  . GLU A 192 ? 0.33030 0.36850 0.39960 0.05290  -0.06750 0.01390  1651 GLU A CG  
2981 C  CD  . GLU A 192 ? 0.41440 0.39590 0.46500 0.05170  -0.04360 0.01790  1651 GLU A CD  
2982 O  OE1 . GLU A 192 ? 0.44710 0.40520 0.49580 0.05600  -0.02850 0.01650  1651 GLU A OE1 
2983 O  OE2 . GLU A 192 ? 0.44660 0.40670 0.48180 0.04740  -0.04610 0.02130  1651 GLU A OE2 
2990 N  N   . ARG A 193 ? 0.17170 0.27920 0.20990 0.03240  -0.04520 -0.00930 1652 ARG A N   
2991 C  CA  . ARG A 193 ? 0.17760 0.26810 0.22040 0.02260  -0.04600 -0.00870 1652 ARG A CA  
2992 C  C   . ARG A 193 ? 0.16590 0.25640 0.22690 0.01460  -0.04030 -0.00380 1652 ARG A C   
2993 O  O   . ARG A 193 ? 0.16870 0.25580 0.25710 0.00470  -0.04080 -0.00830 1652 ARG A O   
2994 C  CB  . ARG A 193 ? 0.19640 0.26860 0.23800 0.02150  -0.03260 -0.01520 1652 ARG A CB  
2995 C  CG  . ARG A 193 ? 0.21200 0.27020 0.25290 0.02520  -0.03800 -0.01780 1652 ARG A CG  
2996 C  CD  . ARG A 193 ? 0.22180 0.27200 0.25140 0.02410  -0.05440 -0.00550 1652 ARG A CD  
2997 N  NE  . ARG A 193 ? 0.21850 0.27000 0.24020 0.02360  -0.06340 0.01190  1652 ARG A NE  
2998 C  CZ  . ARG A 193 ? 0.23120 0.26940 0.25690 0.01490  -0.06360 0.02220  1652 ARG A CZ  
2999 N  NH1 . ARG A 193 ? 0.23900 0.27090 0.28830 0.00790  -0.06690 0.01450  1652 ARG A NH1 
3000 N  NH2 . ARG A 193 ? 0.22970 0.26850 0.24610 0.01250  -0.06960 0.03120  1652 ARG A NH2 
3014 N  N   . LEU A 194 ? 0.17660 0.24840 0.21550 0.01780  -0.03710 0.00190  1653 LEU A N   
3015 C  CA  . LEU A 194 ? 0.17750 0.24130 0.22140 0.02630  -0.02760 0.00800  1653 LEU A CA  
3016 C  C   . LEU A 194 ? 0.17630 0.23840 0.22700 0.01430  -0.03210 0.01820  1653 LEU A C   
3017 O  O   . LEU A 194 ? 0.19060 0.23580 0.24490 0.00250  -0.02730 0.02270  1653 LEU A O   
3018 C  CB  . LEU A 194 ? 0.18790 0.23620 0.23430 0.03390  -0.01540 0.00380  1653 LEU A CB  
3019 C  CG  . LEU A 194 ? 0.19650 0.23270 0.23180 0.04250  -0.00480 0.00350  1653 LEU A CG  
3020 C  CD1 . LEU A 194 ? 0.18880 0.23360 0.23400 0.04530  0.00320  0.01410  1653 LEU A CD1 
3021 C  CD2 . LEU A 194 ? 0.21160 0.23130 0.22620 0.04570  -0.00410 -0.00230 1653 LEU A CD2 
3033 N  N   . GLY A 195 ? 0.16930 0.23650 0.21650 0.01930  -0.03250 0.02030  1654 GLY A N   
3034 C  CA  . GLY A 195 ? 0.16300 0.23380 0.22640 0.01410  -0.01800 0.02070  1654 GLY A CA  
3035 C  C   . GLY A 195 ? 0.16350 0.22880 0.22350 0.01990  -0.01960 0.01610  1654 GLY A C   
3036 O  O   . GLY A 195 ? 0.15410 0.22980 0.23770 0.01840  -0.02900 0.01200  1654 GLY A O   
3040 N  N   . PRO A 196 ? 0.17010 0.22400 0.22120 0.02660  -0.01840 0.01280  1655 PRO A N   
3041 C  CA  . PRO A 196 ? 0.19300 0.22030 0.22080 0.02030  -0.01910 0.01200  1655 PRO A CA  
3042 C  C   . PRO A 196 ? 0.19540 0.22050 0.21300 0.01270  -0.04270 0.02430  1655 PRO A C   
3043 O  O   . PRO A 196 ? 0.23770 0.23140 0.25740 0.00530  -0.04980 0.02530  1655 PRO A O   
3044 C  CB  . PRO A 196 ? 0.21010 0.22570 0.24810 0.02450  0.00570  -0.00350 1655 PRO A CB  
3045 C  CG  . PRO A 196 ? 0.20520 0.22970 0.24970 0.03690  0.00650  -0.00160 1655 PRO A CG  
3046 C  CD  . PRO A 196 ? 0.18600 0.22570 0.23580 0.03370  -0.01180 0.00740  1655 PRO A CD  
3054 N  N   . GLY A 197 ? 0.16010 0.21200 0.19810 0.01240  -0.03520 0.02700  1656 GLY A N   
3055 C  CA  . GLY A 197 ? 0.14420 0.21100 0.21100 0.02200  -0.03180 0.01720  1656 GLY A CA  
3056 C  C   . GLY A 197 ? 0.13780 0.20870 0.20510 0.01860  -0.02450 0.00160  1656 GLY A C   
3057 O  O   . GLY A 197 ? 0.15130 0.20110 0.19900 0.01620  -0.03290 -0.00740 1656 GLY A O   
3061 N  N   . LYS A 198 ? 0.12980 0.21620 0.20350 0.01430  -0.03300 0.00110  1657 LYS A N   
3062 C  CA  . LYS A 198 ? 0.14630 0.22480 0.21370 0.01150  -0.01280 -0.00040 1657 LYS A CA  
3063 C  C   . LYS A 198 ? 0.13360 0.22660 0.24630 0.01020  -0.01950 0.00880  1657 LYS A C   
3064 O  O   . LYS A 198 ? 0.13680 0.22930 0.26050 0.02060  -0.00060 0.01230  1657 LYS A O   
3065 C  CB  . LYS A 198 ? 0.17350 0.23510 0.21730 0.01900  -0.01730 0.00080  1657 LYS A CB  
3066 C  CG  . LYS A 198 ? 0.21830 0.24900 0.23640 0.02290  -0.04390 -0.00100 1657 LYS A CG  
3067 C  CD  . LYS A 198 ? 0.26040 0.25940 0.26280 0.01540  -0.04680 -0.00790 1657 LYS A CD  
3068 C  CE  . LYS A 198 ? 0.25580 0.26230 0.26770 0.01200  -0.03030 -0.00980 1657 LYS A CE  
3069 N  NZ  . LYS A 198 ? 0.21700 0.26310 0.24540 0.00370  -0.03510 -0.02390 1657 LYS A NZ  
3083 N  N   . GLY A 199 ? 0.13130 0.22430 0.24290 0.00770  -0.02000 0.00950  1658 GLY A N   
3084 C  CA  . GLY A 199 ? 0.12820 0.22600 0.24300 0.00790  -0.02790 0.00870  1658 GLY A CA  
3085 C  C   . GLY A 199 ? 0.12190 0.22400 0.23810 0.00600  -0.02270 0.00610  1658 GLY A C   
3086 O  O   . GLY A 199 ? 0.12350 0.22630 0.26580 -0.01370 -0.02310 0.01210  1658 GLY A O   
3090 N  N   . GLU A 200 ? 0.12820 0.22180 0.21270 0.01820  -0.01770 0.00010  1659 GLU A N   
3091 C  CA  . GLU A 200 ? 0.15730 0.22620 0.22140 0.01150  -0.01870 -0.01550 1659 GLU A CA  
3092 C  C   . GLU A 200 ? 0.12950 0.19810 0.19570 0.00440  -0.03250 -0.01760 1659 GLU A C   
3093 O  O   . GLU A 200 ? 0.12150 0.18670 0.20000 0.00120  -0.02100 -0.02060 1659 GLU A O   
3094 C  CB  . GLU A 200 ? 0.20370 0.26100 0.29130 0.02660  0.02310  -0.01770 1659 GLU A CB  
3095 C  CG  . GLU A 200 ? 0.30710 0.30060 0.36320 0.02160  0.02820  -0.02860 1659 GLU A CG  
3096 C  CD  . GLU A 200 ? 0.40640 0.33370 0.42760 0.01160  0.03370  -0.04060 1659 GLU A CD  
3097 O  OE1 . GLU A 200 ? 0.44010 0.33380 0.46050 0.00760  0.03190  -0.04630 1659 GLU A OE1 
3098 O  OE2 . GLU A 200 ? 0.44500 0.35680 0.44320 0.00010  0.02890  -0.03980 1659 GLU A OE2 
3105 N  N   . VAL A 201 ? 0.12040 0.18920 0.19240 0.01070  -0.03230 -0.00430 1660 VAL A N   
3106 C  CA  . VAL A 201 ? 0.11790 0.17840 0.17120 0.00470  -0.02950 0.00500  1660 VAL A CA  
3107 C  C   . VAL A 201 ? 0.11550 0.17120 0.16370 0.00050  -0.01330 0.00200  1660 VAL A C   
3108 O  O   . VAL A 201 ? 0.11940 0.16820 0.17540 -0.01030 0.00270  0.00440  1660 VAL A O   
3109 C  CB  . VAL A 201 ? 0.13690 0.17780 0.16600 0.00680  -0.02190 0.00150  1660 VAL A CB  
3110 C  CG1 . VAL A 201 ? 0.15390 0.18250 0.16580 0.00710  -0.03360 0.01010  1660 VAL A CG1 
3111 C  CG2 . VAL A 201 ? 0.14910 0.18160 0.17200 0.01250  -0.00540 -0.00370 1660 VAL A CG2 
3121 N  N   . ARG A 202 ? 0.11150 0.17010 0.14700 0.00070  -0.02150 -0.00540 1661 ARG A N   
3122 C  CA  . ARG A 202 ? 0.11760 0.17170 0.15200 0.00120  -0.01280 -0.01510 1661 ARG A CA  
3123 C  C   . ARG A 202 ? 0.11720 0.16040 0.17450 0.00560  -0.01320 -0.02230 1661 ARG A C   
3124 O  O   . ARG A 202 ? 0.14930 0.16510 0.18900 0.01130  -0.01680 -0.02580 1661 ARG A O   
3125 C  CB  . ARG A 202 ? 0.14160 0.19130 0.16250 0.00220  -0.00570 -0.01730 1661 ARG A CB  
3126 C  CG  . ARG A 202 ? 0.16170 0.22040 0.22200 0.01500  -0.01230 -0.02020 1661 ARG A CG  
3127 C  CD  . ARG A 202 ? 0.19690 0.24900 0.28930 0.02040  -0.01210 -0.02260 1661 ARG A CD  
3128 N  NE  . ARG A 202 ? 0.22400 0.27340 0.32440 0.03080  -0.01210 -0.03310 1661 ARG A NE  
3129 C  CZ  . ARG A 202 ? 0.24550 0.29410 0.35220 0.04520  0.01000  -0.04080 1661 ARG A CZ  
3130 N  NH1 . ARG A 202 ? 0.24960 0.29970 0.35430 0.05460  0.00660  -0.03980 1661 ARG A NH1 
3131 N  NH2 . ARG A 202 ? 0.25890 0.30370 0.37360 0.04620  0.03630  -0.04510 1661 ARG A NH2 
3145 N  N   . PRO A 203 ? 0.10800 0.15040 0.15850 0.00110  0.00990  -0.01420 1662 PRO A N   
3146 C  CA  . PRO A 203 ? 0.11520 0.15170 0.15830 -0.00160 -0.00080 -0.00840 1662 PRO A CA  
3147 C  C   . PRO A 203 ? 0.11640 0.15320 0.15230 0.00260  0.00660  -0.00600 1662 PRO A C   
3148 O  O   . PRO A 203 ? 0.12820 0.15730 0.14480 0.00390  0.00510  -0.00860 1662 PRO A O   
3149 C  CB  . PRO A 203 ? 0.10910 0.15620 0.14700 -0.00270 0.00220  -0.00840 1662 PRO A CB  
3150 C  CG  . PRO A 203 ? 0.11620 0.15840 0.14110 0.00780  0.00280  -0.00920 1662 PRO A CG  
3151 C  CD  . PRO A 203 ? 0.11780 0.15540 0.14460 0.00540  -0.00130 -0.00960 1662 PRO A CD  
3159 N  N   . GLU A 204 ? 0.12120 0.15580 0.14540 0.01540  0.00130  -0.00980 1663 GLU A N   
3160 C  CA  A GLU A 204 ? 0.13120 0.16230 0.15620 0.02550  -0.00810 -0.00470 1663 GLU A CA  
3161 C  CA  B GLU A 204 ? 0.12720 0.15770 0.14610 0.01690  -0.00280 -0.00560 1663 GLU A CA  
3162 C  C   . GLU A 204 ? 0.12800 0.16040 0.15580 0.02140  -0.00340 -0.00510 1663 GLU A C   
3163 O  O   . GLU A 204 ? 0.13410 0.16700 0.19350 0.02410  -0.01040 -0.00640 1663 GLU A O   
3164 C  CB  A GLU A 204 ? 0.16130 0.17650 0.18210 0.03150  -0.00590 -0.00550 1663 GLU A CB  
3165 C  CB  B GLU A 204 ? 0.13290 0.15820 0.14390 0.01340  -0.00600 -0.00630 1663 GLU A CB  
3166 C  CG  A GLU A 204 ? 0.22370 0.19260 0.22260 0.03370  0.00840  -0.01040 1663 GLU A CG  
3167 C  CG  B GLU A 204 ? 0.14280 0.15870 0.14010 0.00990  -0.00610 -0.00580 1663 GLU A CG  
3168 C  CD  A GLU A 204 ? 0.29810 0.20940 0.27320 0.03170  0.03140  -0.02300 1663 GLU A CD  
3169 C  CD  B GLU A 204 ? 0.15470 0.16010 0.13690 0.00550  -0.00220 -0.00500 1663 GLU A CD  
3170 O  OE1 A GLU A 204 ? 0.31870 0.21600 0.29650 0.03510  0.03740  -0.03420 1663 GLU A OE1 
3171 O  OE1 B GLU A 204 ? 0.16080 0.16170 0.13810 0.01090  -0.00530 -0.00360 1663 GLU A OE1 
3172 O  OE2 A GLU A 204 ? 0.33270 0.21680 0.29500 0.03350  0.02870  -0.01130 1663 GLU A OE2 
3173 O  OE2 B GLU A 204 ? 0.16330 0.16020 0.13430 0.00030  0.00120  -0.00240 1663 GLU A OE2 
3186 N  N   . LEU A 205 ? 0.13210 0.16000 0.15240 0.01680  -0.02110 -0.00850 1664 LEU A N   
3187 C  CA  . LEU A 205 ? 0.14430 0.16210 0.15260 0.02190  -0.03120 -0.00480 1664 LEU A CA  
3188 C  C   . LEU A 205 ? 0.15970 0.16390 0.16350 0.02170  -0.01610 -0.00660 1664 LEU A C   
3189 O  O   . LEU A 205 ? 0.17120 0.16300 0.18620 0.01760  -0.00840 -0.02280 1664 LEU A O   
3190 C  CB  . LEU A 205 ? 0.15800 0.16790 0.16670 0.01720  -0.02070 -0.00240 1664 LEU A CB  
3191 C  CG  . LEU A 205 ? 0.16810 0.17110 0.15750 0.01740  -0.01640 0.00160  1664 LEU A CG  
3192 C  CD1 . LEU A 205 ? 0.17830 0.17300 0.16990 0.02720  -0.01930 0.00410  1664 LEU A CD1 
3193 C  CD2 . LEU A 205 ? 0.18030 0.17280 0.15960 0.01730  0.00630  0.00340  1664 LEU A CD2 
3205 N  N   . GLY A 206 ? 0.16420 0.16530 0.15800 0.01730  -0.00480 -0.00320 1665 GLY A N   
3206 C  CA  . GLY A 206 ? 0.15480 0.17010 0.16850 0.00680  -0.00360 0.00430  1665 GLY A CA  
3207 C  C   . GLY A 206 ? 0.14060 0.17630 0.17350 0.01080  -0.00310 -0.00090 1665 GLY A C   
3208 O  O   . GLY A 206 ? 0.15440 0.18620 0.17420 0.00210  -0.01350 -0.00210 1665 GLY A O   
3212 N  N   . SER A 207 ? 0.14700 0.17410 0.19180 0.01720  -0.00680 0.00710  1666 SER A N   
3213 C  CA  . SER A 207 ? 0.16850 0.17180 0.19530 0.01740  -0.01480 0.01750  1666 SER A CA  
3214 C  C   . SER A 207 ? 0.17810 0.18150 0.18860 0.03350  -0.02900 0.02050  1666 SER A C   
3215 O  O   . SER A 207 ? 0.17530 0.17560 0.20190 0.04060  -0.02760 0.01290  1666 SER A O   
3216 C  CB  . SER A 207 ? 0.17720 0.16460 0.21190 0.01680  -0.01330 0.02270  1666 SER A CB  
3217 O  OG  . SER A 207 ? 0.17260 0.16090 0.21420 0.01360  0.00810  0.02990  1666 SER A OG  
3223 N  N   . ARG A 208 ? 0.19370 0.19960 0.18460 0.04750  -0.02980 0.02920  1667 ARG A N   
3224 C  CA  . ARG A 208 ? 0.22480 0.21580 0.17770 0.04440  -0.01600 0.03400  1667 ARG A CA  
3225 C  C   . ARG A 208 ? 0.21540 0.21460 0.18080 0.04590  -0.00440 0.03770  1667 ARG A C   
3226 O  O   . ARG A 208 ? 0.20210 0.21580 0.19130 0.05160  -0.00530 0.04200  1667 ARG A O   
3227 C  CB  . ARG A 208 ? 0.24760 0.22800 0.20570 0.04340  -0.01700 0.03520  1667 ARG A CB  
3230 N  N   A GLN A 209 ? 0.20840 0.21020 0.18020 0.04440  -0.01120 0.04620  1668 GLN A N   
3231 N  N   B GLN A 209 ? 0.21840 0.21490 0.18130 0.04590  -0.00940 0.04410  1668 GLN A N   
3232 C  CA  A GLN A 209 ? 0.21980 0.20810 0.19160 0.04920  -0.01140 0.05880  1668 GLN A CA  
3233 C  CA  B GLN A 209 ? 0.23010 0.21560 0.19320 0.04800  -0.00930 0.05370  1668 GLN A CA  
3234 C  C   A GLN A 209 ? 0.18720 0.19020 0.16520 0.04310  -0.00740 0.05430  1668 GLN A C   
3235 C  C   B GLN A 209 ? 0.19690 0.19700 0.16500 0.04190  -0.00860 0.05160  1668 GLN A C   
3236 O  O   A GLN A 209 ? 0.18510 0.18610 0.18540 0.04190  0.01690  0.04780  1668 GLN A O   
3237 O  O   B GLN A 209 ? 0.19760 0.19660 0.17470 0.04050  0.00870  0.04800  1668 GLN A O   
3238 C  CB  A GLN A 209 ? 0.27710 0.22750 0.23400 0.05840  -0.01080 0.06480  1668 GLN A CB  
3239 C  CB  B GLN A 209 ? 0.28020 0.23650 0.23720 0.05450  -0.00700 0.05770  1668 GLN A CB  
3240 C  CG  A GLN A 209 ? 0.33300 0.25060 0.28680 0.06970  -0.01300 0.06600  1668 GLN A CG  
3241 C  CG  B GLN A 209 ? 0.33030 0.25840 0.28960 0.05890  -0.00450 0.05740  1668 GLN A CG  
3242 C  CD  A GLN A 209 ? 0.36730 0.26980 0.33550 0.07820  -0.00190 0.06850  1668 GLN A CD  
3243 C  CD  B GLN A 209 ? 0.37050 0.27610 0.34070 0.05830  0.00690  0.05650  1668 GLN A CD  
3244 O  OE1 A GLN A 209 ? 0.34650 0.27250 0.33160 0.09680  0.01340  0.07590  1668 GLN A OE1 
3245 O  OE1 B GLN A 209 ? 0.38520 0.28130 0.35470 0.05940  0.00800  0.05540  1668 GLN A OE1 
3246 N  NE2 A GLN A 209 ? 0.40010 0.27880 0.36880 0.06850  0.00070  0.06360  1668 GLN A NE2 
3247 N  NE2 B GLN A 209 ? 0.38710 0.28320 0.36810 0.05570  0.00910  0.05430  1668 GLN A NE2 
3264 N  N   . ASP A 210 ? 0.17400 0.18160 0.14700 0.03790  -0.01900 0.04180  1669 ASP A N   
3265 C  CA  . ASP A 210 ? 0.14630 0.15610 0.13020 0.01800  -0.01130 0.02310  1669 ASP A CA  
3266 C  C   . ASP A 210 ? 0.13840 0.14620 0.13600 0.01740  -0.00020 0.01180  1669 ASP A C   
3267 O  O   . ASP A 210 ? 0.14410 0.13140 0.15700 0.01480  0.00190  0.01480  1669 ASP A O   
3268 C  CB  . ASP A 210 ? 0.14110 0.15200 0.14180 0.01380  -0.00260 0.01010  1669 ASP A CB  
3269 C  CG  . ASP A 210 ? 0.14320 0.15080 0.16370 0.01780  -0.01060 0.00300  1669 ASP A CG  
3270 O  OD1 . ASP A 210 ? 0.14500 0.15630 0.18160 0.01430  -0.00730 -0.00280 1669 ASP A OD1 
3271 O  OD2 . ASP A 210 ? 0.15620 0.14600 0.18550 0.02150  0.00060  -0.00530 1669 ASP A OD2 
3276 N  N   . VAL A 211 ? 0.14420 0.15520 0.13000 0.02180  -0.00960 0.00430  1670 VAL A N   
3277 C  CA  . VAL A 211 ? 0.17150 0.16810 0.13070 0.01760  -0.01160 0.00440  1670 VAL A CA  
3278 C  C   . VAL A 211 ? 0.18040 0.17730 0.14100 0.02570  -0.00910 0.01830  1670 VAL A C   
3279 O  O   . VAL A 211 ? 0.16000 0.17070 0.16260 0.02600  -0.00930 -0.00050 1670 VAL A O   
3280 C  CB  . VAL A 211 ? 0.16530 0.17180 0.13220 0.00990  -0.02230 -0.00100 1670 VAL A CB  
3281 C  CG1 . VAL A 211 ? 0.17040 0.17530 0.13830 0.00560  -0.02740 -0.02000 1670 VAL A CG1 
3282 C  CG2 . VAL A 211 ? 0.16630 0.17690 0.13650 0.01160  -0.02110 0.00210  1670 VAL A CG2 
3292 N  N   A GLU A 212 ? 0.19350 0.18590 0.14350 0.02650  -0.00450 0.03560  1671 GLU A N   
3293 N  N   B GLU A 212 ? 0.19250 0.18500 0.14280 0.02720  -0.00420 0.03620  1671 GLU A N   
3294 C  CA  A GLU A 212 ? 0.21650 0.19970 0.17360 0.02350  -0.00170 0.04000  1671 GLU A CA  
3295 C  CA  B GLU A 212 ? 0.21550 0.19800 0.17330 0.02510  -0.00150 0.04170  1671 GLU A CA  
3296 C  C   A GLU A 212 ? 0.19540 0.18560 0.15110 0.02240  0.00990  0.03570  1671 GLU A C   
3297 C  C   B GLU A 212 ? 0.19410 0.18490 0.15090 0.02280  0.01050  0.03540  1671 GLU A C   
3298 O  O   A GLU A 212 ? 0.19100 0.18160 0.15930 0.02290  0.01460  0.02970  1671 GLU A O   
3299 O  O   B GLU A 212 ? 0.18900 0.18090 0.16000 0.02250  0.01540  0.02740  1671 GLU A O   
3300 C  CB  A GLU A 212 ? 0.27100 0.23020 0.24550 0.02370  -0.01330 0.05040  1671 GLU A CB  
3301 C  CB  B GLU A 212 ? 0.27270 0.22640 0.24640 0.02800  -0.01580 0.05660  1671 GLU A CB  
3302 C  CG  A GLU A 212 ? 0.33200 0.25880 0.32590 0.02300  -0.02140 0.06060  1671 GLU A CG  
3303 C  CG  B GLU A 212 ? 0.33820 0.25270 0.32900 0.03080  -0.02890 0.07090  1671 GLU A CG  
3304 C  CD  A GLU A 212 ? 0.38670 0.28300 0.39410 0.02400  -0.03350 0.06940  1671 GLU A CD  
3305 C  CD  B GLU A 212 ? 0.39500 0.27560 0.39140 0.03310  -0.03720 0.08290  1671 GLU A CD  
3306 O  OE1 A GLU A 212 ? 0.40300 0.29130 0.41750 0.02150  -0.03930 0.07910  1671 GLU A OE1 
3307 O  OE1 B GLU A 212 ? 0.41890 0.28270 0.40460 0.02850  -0.03780 0.09170  1671 GLU A OE1 
3308 O  OE2 A GLU A 212 ? 0.40870 0.29210 0.41240 0.02570  -0.03830 0.07110  1671 GLU A OE2 
3309 O  OE2 B GLU A 212 ? 0.41160 0.28460 0.41770 0.03800  -0.04100 0.08270  1671 GLU A OE2 
3322 N  N   . ALA A 213 ? 0.18240 0.17500 0.15140 0.02340  0.00760  0.03390  1672 ALA A N   
3323 C  CA  . ALA A 213 ? 0.16630 0.16060 0.14530 0.01180  0.01240  0.02570  1672 ALA A CA  
3324 C  C   . ALA A 213 ? 0.14570 0.15180 0.15070 0.00600  0.01000  0.01690  1672 ALA A C   
3325 O  O   . ALA A 213 ? 0.14030 0.14570 0.17710 0.00320  0.00580  -0.00230 1672 ALA A O   
3326 C  CB  . ALA A 213 ? 0.17680 0.15930 0.14800 0.01780  0.00690  0.03590  1672 ALA A CB  
3332 N  N   . LEU A 214 ? 0.13160 0.15220 0.15200 0.00290  0.00660  0.01040  1673 LEU A N   
3333 C  CA  . LEU A 214 ? 0.12540 0.15650 0.13240 0.00300  0.00820  -0.00040 1673 LEU A CA  
3334 C  C   . LEU A 214 ? 0.15110 0.16010 0.11340 0.00440  0.00500  -0.00220 1673 LEU A C   
3335 O  O   . LEU A 214 ? 0.15560 0.16420 0.12850 0.01650  -0.00760 -0.00640 1673 LEU A O   
3336 C  CB  . LEU A 214 ? 0.14130 0.15810 0.11120 -0.01060 -0.00490 -0.01060 1673 LEU A CB  
3337 C  CG  . LEU A 214 ? 0.14180 0.15990 0.12270 -0.01230 -0.00210 -0.01120 1673 LEU A CG  
3338 C  CD1 . LEU A 214 ? 0.14150 0.16970 0.14190 -0.01880 0.00540  -0.01050 1673 LEU A CD1 
3339 C  CD2 . LEU A 214 ? 0.13710 0.16150 0.11820 -0.01380 -0.00590 -0.00890 1673 LEU A CD2 
3351 N  N   . TRP A 215 ? 0.14530 0.16110 0.11010 0.01090  -0.00530 -0.00180 1674 TRP A N   
3352 C  CA  . TRP A 215 ? 0.15980 0.16920 0.11450 0.01750  0.00020  0.00110  1674 TRP A CA  
3353 C  C   . TRP A 215 ? 0.16380 0.17680 0.12270 0.01440  0.00830  0.00860  1674 TRP A C   
3354 O  O   . TRP A 215 ? 0.16690 0.18030 0.13740 0.01050  0.01720  0.00440  1674 TRP A O   
3355 C  CB  . TRP A 215 ? 0.16580 0.17230 0.13070 0.00600  -0.00710 -0.01310 1674 TRP A CB  
3356 C  CG  . TRP A 215 ? 0.17030 0.17360 0.12220 -0.00310 -0.00770 -0.01670 1674 TRP A CG  
3357 C  CD1 . TRP A 215 ? 0.16340 0.17260 0.12900 -0.00020 -0.02110 -0.01440 1674 TRP A CD1 
3358 C  CD2 . TRP A 215 ? 0.18060 0.17930 0.13000 0.00190  -0.00230 -0.01530 1674 TRP A CD2 
3359 N  NE1 . TRP A 215 ? 0.16440 0.17860 0.13770 -0.00670 -0.01170 -0.01830 1674 TRP A NE1 
3360 C  CE2 . TRP A 215 ? 0.18120 0.18240 0.13660 -0.00510 -0.01020 -0.01760 1674 TRP A CE2 
3361 C  CE3 . TRP A 215 ? 0.19090 0.18440 0.13010 0.00640  0.00780  -0.01360 1674 TRP A CE3 
3362 C  CZ2 . TRP A 215 ? 0.19630 0.18570 0.12800 -0.00680 -0.00540 -0.02080 1674 TRP A CZ2 
3363 C  CZ3 . TRP A 215 ? 0.20770 0.18810 0.13480 0.00750  0.00250  -0.01510 1674 TRP A CZ3 
3364 C  CH2 . TRP A 215 ? 0.20720 0.18580 0.13230 0.00360  -0.00270 -0.02250 1674 TRP A CH2 
3375 N  N   . GLU A 216 ? 0.15780 0.17860 0.13150 0.01380  0.01560  0.01770  1675 GLU A N   
3376 C  CA  A GLU A 216 ? 0.17520 0.17950 0.14240 0.01160  0.01440  0.02780  1675 GLU A CA  
3377 C  CA  B GLU A 216 ? 0.16950 0.17970 0.14060 0.00590  0.01340  0.02560  1675 GLU A CA  
3378 C  C   . GLU A 216 ? 0.16540 0.17580 0.12780 -0.00100 0.01560  0.02540  1675 GLU A C   
3379 O  O   . GLU A 216 ? 0.16840 0.18170 0.14700 -0.00820 0.00470  0.04030  1675 GLU A O   
3380 C  CB  A GLU A 216 ? 0.20320 0.19120 0.18880 0.01760  0.00690  0.03080  1675 GLU A CB  
3381 C  CB  B GLU A 216 ? 0.18430 0.19120 0.18200 -0.00010 0.00430  0.02380  1675 GLU A CB  
3382 C  CG  A GLU A 216 ? 0.24640 0.20760 0.23680 0.01410  -0.00210 0.02570  1675 GLU A CG  
3383 C  CG  B GLU A 216 ? 0.21260 0.20680 0.21860 -0.01350 -0.00300 0.01250  1675 GLU A CG  
3384 C  CD  A GLU A 216 ? 0.28880 0.22260 0.28360 0.01340  -0.01190 0.02090  1675 GLU A CD  
3385 C  CD  B GLU A 216 ? 0.24970 0.22400 0.25790 -0.03210 -0.00270 0.00560  1675 GLU A CD  
3386 O  OE1 A GLU A 216 ? 0.30600 0.22680 0.30850 0.00290  -0.00500 0.01060  1675 GLU A OE1 
3387 O  OE1 B GLU A 216 ? 0.27810 0.23180 0.27590 -0.03850 0.01010  0.00710  1675 GLU A OE1 
3388 O  OE2 A GLU A 216 ? 0.30790 0.22980 0.29180 0.01840  -0.02230 0.03320  1675 GLU A OE2 
3389 O  OE2 B GLU A 216 ? 0.26350 0.23460 0.28920 -0.03560 -0.00020 -0.00010 1675 GLU A OE2 
3402 N  N   . ASN A 217 ? 0.15910 0.16390 0.11380 -0.00120 0.01030  0.01650  1676 ASN A N   
3403 C  CA  . ASN A 217 ? 0.15420 0.15200 0.10700 -0.00510 0.00410  0.01370  1676 ASN A CA  
3404 C  C   . ASN A 217 ? 0.14500 0.14760 0.11340 -0.00720 0.00740  0.00930  1676 ASN A C   
3405 O  O   . ASN A 217 ? 0.14880 0.15440 0.12990 -0.00760 0.01800  -0.00110 1676 ASN A O   
3406 C  CB  . ASN A 217 ? 0.16300 0.15310 0.12390 -0.00970 0.00760  0.00910  1676 ASN A CB  
3407 C  CG  . ASN A 217 ? 0.18220 0.15500 0.16140 -0.00740 0.01000  0.01470  1676 ASN A CG  
3408 O  OD1 . ASN A 217 ? 0.19860 0.15890 0.18880 -0.02350 -0.00540 -0.00010 1676 ASN A OD1 
3409 N  ND2 . ASN A 217 ? 0.19740 0.15000 0.17330 -0.00330 0.01090  0.02910  1676 ASN A ND2 
3416 N  N   . MET A 218 ? 0.15420 0.14250 0.11350 -0.00220 0.02370  0.01020  1677 MET A N   
3417 C  CA  . MET A 218 ? 0.16940 0.13430 0.10910 -0.01230 0.01390  0.00640  1677 MET A CA  
3418 C  C   . MET A 218 ? 0.15290 0.12750 0.11340 -0.00900 0.02000  -0.00290 1677 MET A C   
3419 O  O   . MET A 218 ? 0.14770 0.12220 0.12070 -0.00490 0.00830  -0.01550 1677 MET A O   
3420 C  CB  . MET A 218 ? 0.19990 0.13670 0.10890 -0.01410 -0.00640 0.00900  1677 MET A CB  
3421 C  CG  . MET A 218 ? 0.21660 0.14200 0.13960 -0.01950 -0.00940 0.01440  1677 MET A CG  
3422 S  SD  . MET A 218 ? 0.20570 0.14890 0.18040 -0.02620 -0.03190 0.01140  1677 MET A SD  
3423 C  CE  . MET A 218 ? 0.22930 0.16050 0.18280 -0.02430 -0.04730 0.01760  1677 MET A CE  
3433 N  N   . ALA A 219 ? 0.14390 0.13440 0.13350 -0.00480 0.03520  -0.00250 1678 ALA A N   
3434 C  CA  . ALA A 219 ? 0.14560 0.14420 0.14150 -0.00730 0.04220  0.00060  1678 ALA A CA  
3435 C  C   . ALA A 219 ? 0.14690 0.14890 0.14910 -0.00220 0.02870  0.00300  1678 ALA A C   
3436 O  O   . ALA A 219 ? 0.15650 0.16400 0.17510 0.01930  0.01930  0.01150  1678 ALA A O   
3437 C  CB  . ALA A 219 ? 0.16990 0.14770 0.16340 -0.01520 0.02500  0.00220  1678 ALA A CB  
3443 N  N   . VAL A 220 ? 0.13900 0.12800 0.12350 -0.01130 0.01390  -0.00510 1679 VAL A N   
3444 C  CA  . VAL A 220 ? 0.13810 0.12810 0.10930 -0.00440 0.00710  0.01140  1679 VAL A CA  
3445 C  C   . VAL A 220 ? 0.12350 0.12040 0.09500 0.00160  -0.00510 0.00410  1679 VAL A C   
3446 O  O   . VAL A 220 ? 0.13450 0.12970 0.13100 -0.00500 -0.00820 0.00520  1679 VAL A O   
3447 C  CB  . VAL A 220 ? 0.15320 0.14500 0.12070 -0.00210 0.02700  0.00830  1679 VAL A CB  
3448 C  CG1 . VAL A 220 ? 0.16250 0.15580 0.16790 0.00530  0.02380  -0.00490 1679 VAL A CG1 
3449 C  CG2 . VAL A 220 ? 0.18070 0.15100 0.14210 -0.00200 0.03620  0.00720  1679 VAL A CG2 
3459 N  N   . ILE A 221 ? 0.11750 0.11190 0.11230 0.00740  0.00270  0.00450  1680 ILE A N   
3460 C  CA  . ILE A 221 ? 0.10910 0.11310 0.11980 0.00570  0.00080  0.00070  1680 ILE A CA  
3461 C  C   . ILE A 221 ? 0.11500 0.11900 0.11030 0.00490  0.00610  -0.00220 1680 ILE A C   
3462 O  O   . ILE A 221 ? 0.14190 0.12350 0.12490 0.00280  0.02510  0.00640  1680 ILE A O   
3463 C  CB  . ILE A 221 ? 0.11430 0.11740 0.12420 -0.00210 -0.00110 0.01340  1680 ILE A CB  
3464 C  CG1 . ILE A 221 ? 0.12400 0.12530 0.13530 -0.01610 -0.00820 0.01260  1680 ILE A CG1 
3465 C  CG2 . ILE A 221 ? 0.11680 0.11820 0.12910 0.00470  -0.01350 0.00340  1680 ILE A CG2 
3466 C  CD1 . ILE A 221 ? 0.14510 0.13590 0.13330 -0.00650 -0.00600 0.01340  1680 ILE A CD1 
3478 N  N   . ASP A 222 ? 0.10930 0.11560 0.11200 0.00710  0.00500  -0.00900 1681 ASP A N   
3479 C  CA  . ASP A 222 ? 0.11290 0.11890 0.10430 0.00240  0.00780  -0.02200 1681 ASP A CA  
3480 C  C   . ASP A 222 ? 0.10840 0.12160 0.10650 -0.00490 0.00740  -0.01810 1681 ASP A C   
3481 O  O   . ASP A 222 ? 0.10960 0.12640 0.13590 0.01120  0.00590  -0.02090 1681 ASP A O   
3482 C  CB  . ASP A 222 ? 0.10730 0.12240 0.12220 0.00980  0.01450  -0.02890 1681 ASP A CB  
3483 C  CG  . ASP A 222 ? 0.10250 0.13360 0.13750 -0.00290 0.01780  -0.02270 1681 ASP A CG  
3484 O  OD1 . ASP A 222 ? 0.11480 0.14380 0.19360 -0.00220 0.02110  -0.02950 1681 ASP A OD1 
3485 O  OD2 . ASP A 222 ? 0.11820 0.13510 0.12810 -0.00330 0.02030  -0.01650 1681 ASP A OD2 
3490 N  N   . CYS A 223 ? 0.10710 0.11800 0.11340 -0.00840 0.01310  -0.01330 1682 CYS A N   
3491 C  CA  . CYS A 223 ? 0.10690 0.11690 0.11150 -0.00470 -0.00680 -0.00420 1682 CYS A CA  
3492 C  C   . CYS A 223 ? 0.09080 0.11460 0.11280 -0.00180 -0.00550 -0.00970 1682 CYS A C   
3493 O  O   . CYS A 223 ? 0.10830 0.11740 0.12900 0.01130  -0.00190 -0.00430 1682 CYS A O   
3494 C  CB  . CYS A 223 ? 0.12070 0.12990 0.10820 0.00650  -0.01190 -0.00500 1682 CYS A CB  
3495 S  SG  . CYS A 223 ? 0.13330 0.12720 0.14690 0.01160  -0.00560 0.00360  1682 CYS A SG  
3501 N  N   . PHE A 224 ? 0.09690 0.11510 0.12460 0.00310  0.00030  -0.01630 1683 PHE A N   
3502 C  CA  . PHE A 224 ? 0.10110 0.12160 0.13190 0.00140  0.01190  -0.01290 1683 PHE A CA  
3503 C  C   . PHE A 224 ? 0.10940 0.11680 0.12220 0.00600  0.00960  -0.00840 1683 PHE A C   
3504 O  O   . PHE A 224 ? 0.12200 0.11950 0.15910 0.01470  0.01650  0.01100  1683 PHE A O   
3505 C  CB  . PHE A 224 ? 0.09900 0.13060 0.12870 0.00610  0.00660  -0.01120 1683 PHE A CB  
3506 C  CG  . PHE A 224 ? 0.10600 0.13720 0.11260 0.00470  0.00410  -0.00590 1683 PHE A CG  
3507 C  CD1 . PHE A 224 ? 0.11970 0.14120 0.11330 -0.00230 0.01780  0.00010  1683 PHE A CD1 
3508 C  CD2 . PHE A 224 ? 0.10860 0.14250 0.10400 0.00250  0.00840  0.00330  1683 PHE A CD2 
3509 C  CE1 . PHE A 224 ? 0.12130 0.14870 0.11460 0.00220  0.02140  0.00810  1683 PHE A CE1 
3510 C  CE2 . PHE A 224 ? 0.11140 0.15080 0.09840 -0.00110 0.00800  0.01040  1683 PHE A CE2 
3511 C  CZ  . PHE A 224 ? 0.12600 0.15310 0.10150 0.00100  0.00960  0.00610  1683 PHE A CZ  
3521 N  N   . ALA A 225 ? 0.11420 0.11870 0.12140 -0.00350 0.01440  -0.00770 1684 ALA A N   
3522 C  CA  . ALA A 225 ? 0.10850 0.12600 0.10900 -0.00070 0.01060  -0.00200 1684 ALA A CA  
3523 C  C   . ALA A 225 ? 0.10280 0.12760 0.13100 0.00040  0.00140  -0.00560 1684 ALA A C   
3524 O  O   . ALA A 225 ? 0.10670 0.13180 0.15720 0.00590  0.00350  -0.00040 1684 ALA A O   
3525 C  CB  . ALA A 225 ? 0.12410 0.13500 0.11890 0.00300  0.00500  0.01580  1684 ALA A CB  
3531 N  N   . SER A 226 ? 0.09890 0.12320 0.13290 0.00160  -0.00950 0.00230  1685 SER A N   
3532 C  CA  . SER A 226 ? 0.10690 0.12810 0.12330 -0.00290 0.00510  -0.01170 1685 SER A CA  
3533 C  C   . SER A 226 ? 0.10410 0.12550 0.09170 -0.00370 -0.01470 -0.00730 1685 SER A C   
3534 O  O   . SER A 226 ? 0.10620 0.13330 0.12330 0.00350  -0.01180 0.00330  1685 SER A O   
3535 C  CB  . SER A 226 ? 0.12030 0.13710 0.14850 -0.00640 0.01290  -0.01710 1685 SER A CB  
3536 O  OG  . SER A 226 ? 0.10790 0.13940 0.16340 -0.00660 0.02130  -0.01790 1685 SER A OG  
3542 N  N   . ASP A 227 ? 0.11030 0.12620 0.11150 -0.01080 -0.00130 -0.00720 1686 ASP A N   
3543 C  CA  . ASP A 227 ? 0.10350 0.12080 0.11050 -0.01260 0.00830  -0.01980 1686 ASP A CA  
3544 C  C   . ASP A 227 ? 0.10640 0.12270 0.10670 -0.00560 0.00900  -0.02240 1686 ASP A C   
3545 O  O   . ASP A 227 ? 0.10610 0.12530 0.12100 0.00050  0.00840  -0.02410 1686 ASP A O   
3546 C  CB  . ASP A 227 ? 0.10880 0.11940 0.11880 -0.01460 -0.00350 -0.03260 1686 ASP A CB  
3547 C  CG  . ASP A 227 ? 0.11500 0.11900 0.12880 -0.01530 0.01080  -0.02220 1686 ASP A CG  
3548 O  OD1 . ASP A 227 ? 0.11660 0.12880 0.15730 -0.02120 0.02160  -0.00770 1686 ASP A OD1 
3549 O  OD2 . ASP A 227 ? 0.13370 0.11770 0.14220 0.00560  -0.00040 -0.01810 1686 ASP A OD2 
3554 N  N   . HIS A 228 ? 0.09740 0.12060 0.14140 -0.01080 0.01900  -0.01240 1687 HIS A N   
3555 C  CA  . HIS A 228 ? 0.10170 0.12650 0.15550 -0.00420 0.01340  -0.01750 1687 HIS A CA  
3556 C  C   . HIS A 228 ? 0.10470 0.13370 0.14400 -0.00090 0.00150  -0.01320 1687 HIS A C   
3557 O  O   . HIS A 228 ? 0.11340 0.13340 0.13820 -0.00140 0.00190  -0.00740 1687 HIS A O   
3558 C  CB  . HIS A 228 ? 0.10970 0.12870 0.14670 -0.00270 0.00860  -0.02620 1687 HIS A CB  
3559 C  CG  . HIS A 228 ? 0.11740 0.12860 0.12550 -0.00300 0.00760  -0.02510 1687 HIS A CG  
3560 N  ND1 . HIS A 228 ? 0.13140 0.13370 0.15000 -0.01340 0.01580  -0.02050 1687 HIS A ND1 
3561 C  CD2 . HIS A 228 ? 0.11480 0.13030 0.11920 -0.00440 -0.00150 -0.03540 1687 HIS A CD2 
3562 C  CE1 . HIS A 228 ? 0.12140 0.13780 0.13060 -0.01490 -0.00490 -0.01340 1687 HIS A CE1 
3563 N  NE2 . HIS A 228 ? 0.12890 0.13850 0.12710 -0.01050 0.00770  -0.02300 1687 HIS A NE2 
3571 N  N   . ALA A 229 ? 0.10490 0.14020 0.15850 0.00280  -0.00600 -0.00970 1688 ALA A N   
3572 C  CA  . ALA A 229 ? 0.11940 0.14880 0.14990 0.00270  -0.00030 -0.01490 1688 ALA A CA  
3573 C  C   . ALA A 229 ? 0.11130 0.14830 0.14960 0.01040  -0.00010 -0.00820 1688 ALA A C   
3574 O  O   . ALA A 229 ? 0.11470 0.14760 0.17050 0.00970  -0.00080 0.00270  1688 ALA A O   
3575 C  CB  . ALA A 229 ? 0.12190 0.15300 0.14030 0.00470  -0.00660 -0.02020 1688 ALA A CB  
3581 N  N   . PRO A 230 ? 0.09650 0.15020 0.17150 0.00090  0.00580  -0.00660 1689 PRO A N   
3582 C  CA  . PRO A 230 ? 0.10120 0.15500 0.14400 -0.00430 0.00810  -0.00580 1689 PRO A CA  
3583 C  C   . PRO A 230 ? 0.11450 0.16270 0.13270 0.00420  -0.01060 -0.00700 1689 PRO A C   
3584 O  O   . PRO A 230 ? 0.11740 0.16870 0.13730 -0.00320 -0.01600 -0.00120 1689 PRO A O   
3585 C  CB  . PRO A 230 ? 0.10610 0.15560 0.15710 -0.00960 -0.00040 -0.00270 1689 PRO A CB  
3586 C  CG  . PRO A 230 ? 0.11590 0.15390 0.17620 -0.00930 -0.00330 -0.00140 1689 PRO A CG  
3587 C  CD  . PRO A 230 ? 0.11100 0.15120 0.17580 0.00040  0.01240  -0.00310 1689 PRO A CD  
3595 N  N   . HIS A 231 ? 0.09610 0.16830 0.14990 -0.00650 0.00260  -0.00440 1690 HIS A N   
3596 C  CA  . HIS A 231 ? 0.09810 0.17160 0.15770 -0.00290 -0.00680 -0.01180 1690 HIS A CA  
3597 C  C   . HIS A 231 ? 0.10050 0.17980 0.14470 -0.00340 -0.01420 -0.01040 1690 HIS A C   
3598 O  O   . HIS A 231 ? 0.11190 0.18710 0.15490 0.01100  -0.00950 -0.01330 1690 HIS A O   
3599 C  CB  . HIS A 231 ? 0.11560 0.17110 0.14080 -0.00250 -0.01500 -0.01310 1690 HIS A CB  
3600 C  CG  . HIS A 231 ? 0.13150 0.17130 0.12910 0.00000  -0.00180 -0.01770 1690 HIS A CG  
3601 N  ND1 . HIS A 231 ? 0.14000 0.17050 0.12250 0.00450  -0.01550 -0.01980 1690 HIS A ND1 
3602 C  CD2 . HIS A 231 ? 0.13120 0.17220 0.16530 0.00470  0.00600  -0.02240 1690 HIS A CD2 
3603 C  CE1 . HIS A 231 ? 0.14740 0.17440 0.14750 0.00840  -0.02320 -0.02160 1690 HIS A CE1 
3604 N  NE2 . HIS A 231 ? 0.14270 0.17140 0.16700 0.00000  -0.00140 -0.03030 1690 HIS A NE2 
3612 N  N   . THR A 232 ? 0.10570 0.18260 0.16760 -0.01710 -0.01990 -0.01180 1691 THR A N   
3613 C  CA  . THR A 232 ? 0.11770 0.18900 0.18710 -0.01570 -0.01030 -0.01820 1691 THR A CA  
3614 C  C   . THR A 232 ? 0.11520 0.18730 0.16710 -0.01110 -0.00610 -0.03010 1691 THR A C   
3615 O  O   . THR A 232 ? 0.11110 0.18720 0.18310 -0.00540 -0.00030 -0.03660 1691 THR A O   
3616 C  CB  . THR A 232 ? 0.12560 0.19690 0.22320 -0.02410 -0.01910 -0.01430 1691 THR A CB  
3617 O  OG1 . THR A 232 ? 0.12740 0.19730 0.22320 -0.02110 0.00100  -0.01030 1691 THR A OG1 
3618 C  CG2 . THR A 232 ? 0.13070 0.20320 0.25790 -0.02390 -0.01950 -0.01300 1691 THR A CG2 
3626 N  N   . LEU A 233 ? 0.11670 0.19280 0.16710 -0.00870 -0.00540 -0.02280 1692 LEU A N   
3627 C  CA  . LEU A 233 ? 0.12630 0.20070 0.16220 -0.00720 -0.01990 -0.01370 1692 LEU A CA  
3628 C  C   . LEU A 233 ? 0.12790 0.20110 0.17900 -0.01170 -0.00950 -0.00480 1692 LEU A C   
3629 O  O   . LEU A 233 ? 0.12010 0.19350 0.20410 -0.00320 -0.01260 -0.00440 1692 LEU A O   
3630 C  CB  . LEU A 233 ? 0.14520 0.20710 0.17060 -0.01030 -0.00760 -0.02430 1692 LEU A CB  
3631 C  CG  . LEU A 233 ? 0.16740 0.21670 0.18110 -0.01070 -0.00780 -0.01660 1692 LEU A CG  
3632 C  CD1 . LEU A 233 ? 0.18400 0.21920 0.18440 -0.00600 0.01340  -0.00920 1692 LEU A CD1 
3633 C  CD2 . LEU A 233 ? 0.18450 0.22060 0.17880 0.00020  -0.00330 -0.01380 1692 LEU A CD2 
3645 N  N   . GLU A 234 ? 0.11430 0.21010 0.18700 -0.02470 0.00070  -0.00710 1693 GLU A N   
3646 C  CA  . GLU A 234 ? 0.12580 0.22130 0.20340 -0.02520 0.00160  -0.01120 1693 GLU A CA  
3647 C  C   . GLU A 234 ? 0.12580 0.21440 0.18480 -0.00420 -0.00070 -0.00640 1693 GLU A C   
3648 O  O   . GLU A 234 ? 0.12760 0.22070 0.17370 0.00540  0.00460  0.00040  1693 GLU A O   
3649 C  CB  . GLU A 234 ? 0.14290 0.23720 0.24500 -0.03560 0.00520  -0.02120 1693 GLU A CB  
3650 C  CG  . GLU A 234 ? 0.19130 0.25530 0.30240 -0.02590 0.00680  -0.01870 1693 GLU A CG  
3651 C  CD  . GLU A 234 ? 0.23660 0.26780 0.33940 -0.01420 0.00810  -0.01490 1693 GLU A CD  
3652 O  OE1 . GLU A 234 ? 0.24070 0.27450 0.34750 -0.00620 -0.00230 -0.00780 1693 GLU A OE1 
3653 O  OE2 . GLU A 234 ? 0.27530 0.27310 0.36120 -0.01910 0.02120  -0.02230 1693 GLU A OE2 
3660 N  N   . GLU A 235 ? 0.10420 0.20490 0.16850 0.00750  -0.00810 -0.01400 1694 GLU A N   
3661 C  CA  . GLU A 235 ? 0.10490 0.20600 0.16210 0.00960  -0.01030 -0.00320 1694 GLU A CA  
3662 C  C   . GLU A 235 ? 0.10600 0.19980 0.16880 0.01100  0.00140  -0.00460 1694 GLU A C   
3663 O  O   . GLU A 235 ? 0.11900 0.19600 0.18830 0.00680  0.00130  -0.00240 1694 GLU A O   
3664 C  CB  . GLU A 235 ? 0.11020 0.20730 0.15840 0.00960  0.00510  0.00060  1694 GLU A CB  
3665 C  CG  . GLU A 235 ? 0.12590 0.21190 0.16590 0.01220  0.01370  0.00810  1694 GLU A CG  
3666 C  CD  . GLU A 235 ? 0.15030 0.21530 0.18470 0.00600  0.01420  0.00990  1694 GLU A CD  
3667 O  OE1 . GLU A 235 ? 0.13290 0.20960 0.20030 0.00250  0.00610  -0.00300 1694 GLU A OE1 
3668 O  OE2 . GLU A 235 ? 0.17020 0.22400 0.20640 0.00680  0.00090  0.01700  1694 GLU A OE2 
3675 N  N   . LYS A 236 ? 0.11610 0.20290 0.16100 0.00920  0.00330  -0.00420 1695 LYS A N   
3676 C  CA  . LYS A 236 ? 0.10740 0.20980 0.16100 0.00480  -0.00030 -0.01130 1695 LYS A CA  
3677 C  C   . LYS A 236 ? 0.12240 0.22910 0.17410 0.00950  -0.00670 -0.01160 1695 LYS A C   
3678 O  O   . LYS A 236 ? 0.13300 0.22870 0.19830 0.00850  -0.00620 -0.02540 1695 LYS A O   
3679 C  CB  . LYS A 236 ? 0.11850 0.20610 0.15560 -0.00180 -0.01350 -0.01660 1695 LYS A CB  
3680 C  CG  . LYS A 236 ? 0.12640 0.20400 0.15430 0.00250  -0.00840 -0.01540 1695 LYS A CG  
3681 C  CD  . LYS A 236 ? 0.12400 0.20140 0.15730 0.00740  -0.01060 -0.01260 1695 LYS A CD  
3682 C  CE  . LYS A 236 ? 0.11380 0.19650 0.15550 0.01350  -0.01040 -0.01680 1695 LYS A CE  
3683 N  NZ  . LYS A 236 ? 0.11050 0.19400 0.16940 0.00470  0.00340  -0.02100 1695 LYS A NZ  
3697 N  N   . CYS A 237 ? 0.11460 0.25310 0.17060 0.02320  -0.01110 -0.00180 1696 CYS A N   
3698 C  CA  . CYS A 237 ? 0.12260 0.27570 0.15590 0.03780  -0.00370 0.00040  1696 CYS A CA  
3699 C  C   . CYS A 237 ? 0.12870 0.26420 0.19010 0.02460  0.00820  0.00820  1696 CYS A C   
3700 O  O   . CYS A 237 ? 0.13620 0.25060 0.20670 0.02720  0.00790  0.00710  1696 CYS A O   
3701 C  CB  . CYS A 237 ? 0.14780 0.31570 0.15200 0.06590  -0.02430 -0.00700 1696 CYS A CB  
3702 S  SG  . CYS A 237 ? 0.19360 0.35380 0.16630 0.10700  -0.01560 -0.00620 1696 CYS A SG  
3708 N  N   . GLY A 238 ? 0.13780 0.26930 0.19910 0.01530  0.01790  0.01690  1697 GLY A N   
3709 C  CA  . GLY A 238 ? 0.14520 0.28030 0.20350 0.01260  0.02210  0.01920  1697 GLY A CA  
3710 C  C   . GLY A 238 ? 0.16820 0.29450 0.22110 0.01450  0.01610  0.01370  1697 GLY A C   
3711 O  O   . GLY A 238 ? 0.19960 0.29320 0.22850 0.00510  0.01870  -0.00260 1697 GLY A O   
3715 N  N   . SER A 239 ? 0.19020 0.31120 0.24580 0.02580  0.02020  0.01170  1698 SER A N   
3716 C  CA  . SER A 239 ? 0.25510 0.32900 0.28500 0.02740  0.03290  0.00670  1698 SER A CA  
3717 C  C   . SER A 239 ? 0.26250 0.33260 0.30680 0.03500  0.02300  -0.00420 1698 SER A C   
3718 O  O   . SER A 239 ? 0.29180 0.33440 0.33270 0.04430  0.02590  -0.02080 1698 SER A O   
3719 C  CB  . SER A 239 ? 0.29990 0.33990 0.31110 0.02870  0.04820  0.01080  1698 SER A CB  
3720 O  OG  . SER A 239 ? 0.33510 0.34680 0.34620 0.02700  0.05820  0.01320  1698 SER A OG  
3726 N  N   . ARG A 240 ? 0.21970 0.33340 0.29560 0.03070  0.03390  0.00010  1699 ARG A N   
3727 C  CA  . ARG A 240 ? 0.22640 0.32590 0.29750 0.03580  0.03310  0.00060  1699 ARG A CA  
3728 C  C   . ARG A 240 ? 0.18980 0.30740 0.28090 0.03210  0.03710  -0.00180 1699 ARG A C   
3729 O  O   . ARG A 240 ? 0.19550 0.31140 0.28650 0.02280  0.01240  0.01570  1699 ARG A O   
3730 C  CB  . ARG A 240 ? 0.26150 0.33140 0.30010 0.04750  0.04170  0.00230  1699 ARG A CB  
3733 N  N   . PRO A 241 ? 0.16990 0.28610 0.27400 0.02390  0.04320  -0.02160 1700 PRO A N   
3734 C  CA  . PRO A 241 ? 0.14930 0.26590 0.26540 0.00900  0.03960  -0.03100 1700 PRO A CA  
3735 C  C   . PRO A 241 ? 0.14220 0.23940 0.24490 -0.01320 0.01900  -0.03460 1700 PRO A C   
3736 O  O   . PRO A 241 ? 0.16910 0.23650 0.26490 -0.02520 0.01990  -0.04010 1700 PRO A O   
3737 C  CB  . PRO A 241 ? 0.17610 0.27800 0.28930 0.01210  0.03010  -0.03020 1700 PRO A CB  
3738 C  CG  . PRO A 241 ? 0.20950 0.28480 0.30980 0.01930  0.04290  -0.02980 1700 PRO A CG  
3739 C  CD  . PRO A 241 ? 0.19480 0.28520 0.28780 0.02600  0.05720  -0.02860 1700 PRO A CD  
3747 N  N   . PRO A 242 ? 0.12520 0.21690 0.20880 -0.01400 0.01890  -0.03410 1701 PRO A N   
3748 C  CA  . PRO A 242 ? 0.13260 0.20480 0.18520 -0.02120 0.00800  -0.03540 1701 PRO A CA  
3749 C  C   . PRO A 242 ? 0.13240 0.20440 0.16810 -0.01420 0.00840  -0.03710 1701 PRO A C   
3750 O  O   . PRO A 242 ? 0.12840 0.20950 0.16800 -0.01490 0.00750  -0.02640 1701 PRO A O   
3751 C  CB  . PRO A 242 ? 0.15180 0.20660 0.19810 -0.01780 0.00870  -0.02690 1701 PRO A CB  
3752 C  CG  . PRO A 242 ? 0.16280 0.21010 0.21920 -0.01250 0.00520  -0.02490 1701 PRO A CG  
3753 C  CD  . PRO A 242 ? 0.14890 0.21030 0.20600 -0.01050 0.01500  -0.03000 1701 PRO A CD  
3761 N  N   . PRO A 243 ? 0.15060 0.20330 0.16850 -0.02050 0.00670  -0.05240 1702 PRO A N   
3762 C  CA  . PRO A 243 ? 0.13930 0.19420 0.15610 -0.01770 0.00960  -0.04020 1702 PRO A CA  
3763 C  C   . PRO A 243 ? 0.11690 0.18110 0.13680 -0.00440 -0.01220 -0.02000 1702 PRO A C   
3764 O  O   . PRO A 243 ? 0.13900 0.18230 0.16880 -0.00030 -0.01140 -0.01060 1702 PRO A O   
3765 C  CB  . PRO A 243 ? 0.15060 0.20490 0.15280 -0.02770 0.00820  -0.04040 1702 PRO A CB  
3766 C  CG  . PRO A 243 ? 0.16440 0.21240 0.16670 -0.03380 -0.00400 -0.04490 1702 PRO A CG  
3767 C  CD  . PRO A 243 ? 0.16490 0.21320 0.16540 -0.03410 0.00240  -0.04450 1702 PRO A CD  
3775 N  N   . GLY A 244 ? 0.10510 0.16580 0.12640 -0.00020 -0.01550 -0.02000 1703 GLY A N   
3776 C  CA  . GLY A 244 ? 0.09700 0.15940 0.13770 0.00530  -0.00550 -0.01650 1703 GLY A CA  
3777 C  C   . GLY A 244 ? 0.09600 0.15620 0.15180 0.00350  0.00120  -0.01300 1703 GLY A C   
3778 O  O   . GLY A 244 ? 0.09510 0.15500 0.16300 0.00120  -0.00140 -0.00270 1703 GLY A O   
3782 N  N   . PHE A 245 ? 0.09250 0.15810 0.14600 -0.00050 -0.00680 -0.01200 1704 PHE A N   
3783 C  CA  . PHE A 245 ? 0.10190 0.16000 0.12580 0.00080  -0.00140 -0.00760 1704 PHE A CA  
3784 C  C   . PHE A 245 ? 0.09850 0.15320 0.12950 0.00060  -0.00850 -0.00500 1704 PHE A C   
3785 O  O   . PHE A 245 ? 0.10330 0.14840 0.15160 0.00250  0.00820  0.01020  1704 PHE A O   
3786 C  CB  . PHE A 245 ? 0.11400 0.15800 0.14230 -0.00130 -0.00660 -0.00960 1704 PHE A CB  
3787 C  CG  . PHE A 245 ? 0.10510 0.15330 0.13630 -0.00460 0.00490  -0.00740 1704 PHE A CG  
3788 C  CD1 . PHE A 245 ? 0.12150 0.15980 0.16030 -0.01070 -0.01430 0.00060  1704 PHE A CD1 
3789 C  CD2 . PHE A 245 ? 0.11100 0.15310 0.13860 -0.00510 0.00510  -0.01050 1704 PHE A CD2 
3790 C  CE1 . PHE A 245 ? 0.13070 0.16220 0.14940 -0.00470 -0.00080 -0.00290 1704 PHE A CE1 
3791 C  CE2 . PHE A 245 ? 0.13580 0.15790 0.16430 0.00070  0.00990  -0.00140 1704 PHE A CE2 
3792 C  CZ  . PHE A 245 ? 0.13910 0.16210 0.15840 -0.00080 0.00110  -0.00300 1704 PHE A CZ  
3802 N  N   . PRO A 246 ? 0.09440 0.15690 0.14150 0.00410  -0.01130 -0.00630 1705 PRO A N   
3803 C  CA  . PRO A 246 ? 0.09990 0.16170 0.15330 -0.00120 -0.00160 -0.00340 1705 PRO A CA  
3804 C  C   . PRO A 246 ? 0.11150 0.15850 0.15150 -0.00280 0.00380  -0.00680 1705 PRO A C   
3805 O  O   . PRO A 246 ? 0.11950 0.16680 0.14330 0.00350  0.00680  -0.01780 1705 PRO A O   
3806 C  CB  . PRO A 246 ? 0.11130 0.17070 0.16670 -0.00640 -0.00210 -0.00370 1705 PRO A CB  
3807 C  CG  . PRO A 246 ? 0.12270 0.17220 0.17950 -0.00750 -0.01010 -0.00600 1705 PRO A CG  
3808 C  CD  . PRO A 246 ? 0.11020 0.16720 0.15690 0.00720  -0.02610 -0.00340 1705 PRO A CD  
3816 N  N   . GLY A 247 ? 0.10170 0.14670 0.15610 -0.00960 0.00400  -0.00130 1706 GLY A N   
3817 C  CA  . GLY A 247 ? 0.10630 0.14400 0.14470 -0.00770 0.00070  0.00150  1706 GLY A CA  
3818 C  C   . GLY A 247 ? 0.11330 0.14130 0.14800 -0.00650 -0.00390 -0.00600 1706 GLY A C   
3819 O  O   . GLY A 247 ? 0.12550 0.13870 0.16510 -0.00240 0.00430  -0.00460 1706 GLY A O   
3823 N  N   . LEU A 248 ? 0.10840 0.13890 0.13190 -0.00350 -0.00720 -0.02270 1707 LEU A N   
3824 C  CA  . LEU A 248 ? 0.10300 0.13910 0.13340 -0.01360 -0.01260 -0.02630 1707 LEU A CA  
3825 C  C   . LEU A 248 ? 0.11120 0.14170 0.14070 -0.01520 -0.00910 -0.02300 1707 LEU A C   
3826 O  O   . LEU A 248 ? 0.11340 0.14520 0.15420 -0.01870 0.00770  -0.01310 1707 LEU A O   
3827 C  CB  . LEU A 248 ? 0.11780 0.13600 0.14470 -0.01260 -0.00160 -0.02060 1707 LEU A CB  
3828 C  CG  . LEU A 248 ? 0.13650 0.13530 0.13180 -0.00700 0.00320  -0.01400 1707 LEU A CG  
3829 C  CD1 . LEU A 248 ? 0.13010 0.13420 0.12890 -0.00170 0.01650  -0.01690 1707 LEU A CD1 
3830 C  CD2 . LEU A 248 ? 0.13810 0.13800 0.16520 -0.01500 -0.02830 -0.02020 1707 LEU A CD2 
3842 N  N   . GLU A 249 ? 0.12230 0.14510 0.14010 -0.02520 -0.01960 -0.02900 1708 GLU A N   
3843 C  CA  . GLU A 249 ? 0.12580 0.14600 0.14870 -0.01940 -0.01240 -0.03590 1708 GLU A CA  
3844 C  C   . GLU A 249 ? 0.13990 0.15380 0.14820 -0.01510 -0.00990 -0.03620 1708 GLU A C   
3845 O  O   . GLU A 249 ? 0.16170 0.15640 0.17400 -0.00110 0.00220  -0.04390 1708 GLU A O   
3846 C  CB  . GLU A 249 ? 0.13520 0.14250 0.16820 -0.01990 -0.01850 -0.04460 1708 GLU A CB  
3847 C  CG  . GLU A 249 ? 0.13960 0.14400 0.17720 -0.01890 -0.01060 -0.04250 1708 GLU A CG  
3848 C  CD  . GLU A 249 ? 0.13610 0.14760 0.18560 -0.02390 -0.00910 -0.03970 1708 GLU A CD  
3849 O  OE1 . GLU A 249 ? 0.14660 0.14780 0.18400 -0.03620 -0.00010 -0.03650 1708 GLU A OE1 
3850 O  OE2 . GLU A 249 ? 0.13700 0.15660 0.21720 -0.02600 -0.01270 -0.03220 1708 GLU A OE2 
3857 N  N   . THR A 250 ? 0.12460 0.15400 0.13660 -0.02150 -0.00860 -0.02490 1709 THR A N   
3858 C  CA  . THR A 250 ? 0.12530 0.15380 0.13780 -0.01670 -0.00470 -0.02240 1709 THR A CA  
3859 C  C   . THR A 250 ? 0.12210 0.15060 0.11840 -0.00930 -0.00940 -0.02020 1709 THR A C   
3860 O  O   . THR A 250 ? 0.13490 0.15330 0.13160 -0.00730 -0.00110 -0.00550 1709 THR A O   
3861 C  CB  . THR A 250 ? 0.12310 0.16200 0.13760 -0.00630 -0.01460 -0.01510 1709 THR A CB  
3862 O  OG1 . THR A 250 ? 0.12400 0.15630 0.14530 -0.01050 -0.00070 -0.01610 1709 THR A OG1 
3863 C  CG2 . THR A 250 ? 0.12720 0.16720 0.15950 -0.00120 -0.01130 -0.01640 1709 THR A CG2 
3871 N  N   . MET A 251 ? 0.11770 0.15040 0.13850 -0.00870 -0.00620 -0.01760 1710 MET A N   
3872 C  CA  . MET A 251 ? 0.11980 0.14780 0.13060 -0.00670 -0.00490 -0.02510 1710 MET A CA  
3873 C  C   . MET A 251 ? 0.12370 0.14430 0.12350 -0.01210 0.00240  -0.02340 1710 MET A C   
3874 O  O   . MET A 251 ? 0.12980 0.14560 0.13840 -0.00470 0.00130  -0.00910 1710 MET A O   
3875 C  CB  . MET A 251 ? 0.12010 0.15410 0.14230 -0.00100 0.00250  -0.03210 1710 MET A CB  
3876 C  CG  . MET A 251 ? 0.11900 0.15430 0.14910 -0.00240 0.01810  -0.03020 1710 MET A CG  
3877 S  SD  . MET A 251 ? 0.12510 0.14930 0.14590 0.00100  -0.00120 -0.02130 1710 MET A SD  
3878 C  CE  . MET A 251 ? 0.13650 0.15600 0.15860 0.00140  0.00490  -0.01280 1710 MET A CE  
3888 N  N   . LEU A 252 ? 0.12350 0.14340 0.11930 -0.01410 0.01000  -0.02780 1711 LEU A N   
3889 C  CA  . LEU A 252 ? 0.13670 0.14570 0.12100 -0.02020 0.01080  -0.03110 1711 LEU A CA  
3890 C  C   . LEU A 252 ? 0.13990 0.16320 0.14780 -0.01590 -0.00170 -0.02230 1711 LEU A C   
3891 O  O   . LEU A 252 ? 0.13630 0.17010 0.15780 -0.01340 -0.01040 -0.01840 1711 LEU A O   
3892 C  CB  . LEU A 252 ? 0.13900 0.14260 0.12250 -0.01570 0.01140  -0.03130 1711 LEU A CB  
3893 C  CG  . LEU A 252 ? 0.14940 0.14320 0.13440 -0.01820 0.01600  -0.03580 1711 LEU A CG  
3894 C  CD1 . LEU A 252 ? 0.13460 0.15440 0.15710 -0.01540 0.03400  -0.03240 1711 LEU A CD1 
3895 C  CD2 . LEU A 252 ? 0.14670 0.14060 0.15390 -0.01440 -0.00570 -0.04140 1711 LEU A CD2 
3907 N  N   . PRO A 253 ? 0.14010 0.17510 0.14550 -0.02130 -0.01300 -0.01790 1712 PRO A N   
3908 C  CA  . PRO A 253 ? 0.14790 0.18560 0.14180 -0.01970 -0.01120 -0.02300 1712 PRO A CA  
3909 C  C   . PRO A 253 ? 0.12970 0.18540 0.11060 -0.01240 -0.01080 -0.02300 1712 PRO A C   
3910 O  O   . PRO A 253 ? 0.14640 0.18970 0.12020 -0.00000 -0.01450 -0.01920 1712 PRO A O   
3911 C  CB  . PRO A 253 ? 0.16630 0.19350 0.17670 -0.02360 -0.02550 -0.01290 1712 PRO A CB  
3912 C  CG  . PRO A 253 ? 0.16620 0.19610 0.17350 -0.01930 -0.02450 -0.00860 1712 PRO A CG  
3913 C  CD  . PRO A 253 ? 0.14090 0.18540 0.14270 -0.01800 -0.01280 -0.00810 1712 PRO A CD  
3921 N  N   . LEU A 254 ? 0.12450 0.18400 0.12780 -0.01600 -0.00100 -0.02050 1713 LEU A N   
3922 C  CA  . LEU A 254 ? 0.12660 0.18110 0.13610 -0.01430 0.00530  -0.01010 1713 LEU A CA  
3923 C  C   . LEU A 254 ? 0.13540 0.17420 0.10970 -0.01350 -0.01200 -0.00910 1713 LEU A C   
3924 O  O   . LEU A 254 ? 0.15150 0.17960 0.12260 -0.00540 -0.01800 -0.01200 1713 LEU A O   
3925 C  CB  . LEU A 254 ? 0.10700 0.17840 0.14740 -0.00640 0.00210  -0.00730 1713 LEU A CB  
3926 C  CG  . LEU A 254 ? 0.12010 0.18300 0.15480 -0.01290 -0.01390 -0.01080 1713 LEU A CG  
3927 C  CD1 . LEU A 254 ? 0.11650 0.18470 0.14590 -0.01400 -0.00770 -0.01230 1713 LEU A CD1 
3928 C  CD2 . LEU A 254 ? 0.10750 0.19030 0.18240 -0.00550 -0.02200 -0.01500 1713 LEU A CD2 
3940 N  N   . LEU A 255 ? 0.12480 0.16830 0.12560 -0.00970 -0.00630 -0.01650 1714 LEU A N   
3941 C  CA  . LEU A 255 ? 0.12690 0.16970 0.11400 -0.00650 -0.00230 -0.02080 1714 LEU A CA  
3942 C  C   . LEU A 255 ? 0.13430 0.17520 0.12020 -0.00400 0.00340  -0.02120 1714 LEU A C   
3943 O  O   . LEU A 255 ? 0.13430 0.17580 0.14020 -0.01150 0.01510  -0.01100 1714 LEU A O   
3944 C  CB  . LEU A 255 ? 0.13810 0.17690 0.10760 -0.01090 0.00030  -0.01730 1714 LEU A CB  
3945 C  CG  . LEU A 255 ? 0.14010 0.18470 0.11120 -0.00870 -0.01240 -0.01010 1714 LEU A CG  
3946 C  CD1 . LEU A 255 ? 0.15400 0.18910 0.11080 -0.00550 -0.01340 -0.01040 1714 LEU A CD1 
3947 C  CD2 . LEU A 255 ? 0.14870 0.18570 0.13530 0.00030  -0.02540 -0.01000 1714 LEU A CD2 
3959 N  N   . LEU A 256 ? 0.13690 0.18050 0.13910 0.00070  0.00110  -0.03510 1715 LEU A N   
3960 C  CA  . LEU A 256 ? 0.14590 0.18640 0.15800 -0.00160 0.01370  -0.03760 1715 LEU A CA  
3961 C  C   . LEU A 256 ? 0.15280 0.19670 0.14680 -0.01010 0.01130  -0.03490 1715 LEU A C   
3962 O  O   . LEU A 256 ? 0.16690 0.19570 0.14500 -0.01390 0.01980  -0.02820 1715 LEU A O   
3963 C  CB  . LEU A 256 ? 0.15930 0.18210 0.15840 0.00080  0.02060  -0.03260 1715 LEU A CB  
3964 C  CG  . LEU A 256 ? 0.18970 0.17900 0.16250 0.00620  0.02340  -0.02960 1715 LEU A CG  
3965 C  CD1 . LEU A 256 ? 0.21980 0.17650 0.18410 0.01210  0.01590  -0.03810 1715 LEU A CD1 
3966 C  CD2 . LEU A 256 ? 0.19090 0.18200 0.17980 0.00710  0.03080  -0.01910 1715 LEU A CD2 
3978 N  N   . THR A 257 ? 0.16110 0.20680 0.15890 -0.00340 -0.00810 -0.02820 1716 THR A N   
3979 C  CA  . THR A 257 ? 0.16240 0.20700 0.15290 -0.00070 -0.00760 -0.01790 1716 THR A CA  
3980 C  C   . THR A 257 ? 0.16770 0.20040 0.14080 -0.00250 -0.00430 -0.01030 1716 THR A C   
3981 O  O   . THR A 257 ? 0.17120 0.19900 0.17250 -0.01000 -0.00620 -0.01140 1716 THR A O   
3982 C  CB  . THR A 257 ? 0.15850 0.21670 0.15110 -0.00670 -0.01270 -0.01090 1716 THR A CB  
3983 O  OG1 . THR A 257 ? 0.16230 0.22130 0.15090 -0.01030 -0.01730 -0.00200 1716 THR A OG1 
3984 C  CG2 . THR A 257 ? 0.16910 0.22240 0.16750 -0.00580 -0.02290 -0.00310 1716 THR A CG2 
3992 N  N   . ALA A 258 ? 0.16410 0.19740 0.12250 0.00230  0.01060  -0.00740 1717 ALA A N   
3993 C  CA  . ALA A 258 ? 0.15500 0.19580 0.13360 0.00250  0.01010  -0.00650 1717 ALA A CA  
3994 C  C   . ALA A 258 ? 0.16120 0.20170 0.13630 -0.01050 0.00900  -0.00490 1717 ALA A C   
3995 O  O   . ALA A 258 ? 0.18080 0.20670 0.16880 -0.00610 0.01490  -0.00650 1717 ALA A O   
3996 C  CB  . ALA A 258 ? 0.15110 0.19500 0.15620 0.00970  0.01090  -0.00890 1717 ALA A CB  
4002 N  N   . VAL A 259 ? 0.15190 0.20540 0.11750 -0.01730 0.02200  -0.01900 1718 VAL A N   
4003 C  CA  . VAL A 259 ? 0.17180 0.21270 0.14810 -0.02020 0.04880  -0.02800 1718 VAL A CA  
4004 C  C   . VAL A 259 ? 0.21430 0.23190 0.16180 -0.03180 0.05860  -0.03210 1718 VAL A C   
4005 O  O   . VAL A 259 ? 0.23690 0.23450 0.17170 -0.03630 0.07130  -0.02790 1718 VAL A O   
4006 C  CB  . VAL A 259 ? 0.16490 0.20780 0.16480 -0.01230 0.05440  -0.03250 1718 VAL A CB  
4007 C  CG1 . VAL A 259 ? 0.17990 0.20860 0.18390 -0.01100 0.04060  -0.04230 1718 VAL A CG1 
4008 C  CG2 . VAL A 259 ? 0.16160 0.20450 0.17280 -0.00120 0.03820  -0.03780 1718 VAL A CG2 
4018 N  N   . SER A 260 ? 0.25350 0.24810 0.17490 -0.04290 0.03070  -0.03100 1719 SER A N   
4019 C  CA  A SER A 260 ? 0.26800 0.25720 0.18370 -0.04760 0.02440  -0.02340 1719 SER A CA  
4020 C  CA  B SER A 260 ? 0.27880 0.25690 0.18080 -0.04190 0.01980  -0.03170 1719 SER A CA  
4021 C  C   . SER A 260 ? 0.29210 0.26370 0.18240 -0.04740 0.01950  -0.02460 1719 SER A C   
4022 O  O   . SER A 260 ? 0.34180 0.26750 0.20710 -0.04950 0.03210  -0.01770 1719 SER A O   
4023 C  CB  A SER A 260 ? 0.26300 0.25910 0.20010 -0.04970 0.02560  -0.01390 1719 SER A CB  
4024 C  CB  B SER A 260 ? 0.29800 0.25910 0.19380 -0.03160 0.01310  -0.03830 1719 SER A CB  
4025 O  OG  A SER A 260 ? 0.26060 0.26000 0.20830 -0.05230 0.03080  -0.00670 1719 SER A OG  
4026 O  OG  B SER A 260 ? 0.32130 0.26070 0.20460 -0.02750 -0.00150 -0.04340 1719 SER A OG  
4037 N  N   . GLU A 261 ? 0.28040 0.27090 0.17860 -0.04550 -0.00210 -0.02210 1720 GLU A N   
4038 C  CA  . GLU A 261 ? 0.28300 0.27590 0.20880 -0.04380 -0.02180 -0.01430 1720 GLU A CA  
4039 C  C   . GLU A 261 ? 0.28810 0.26450 0.21230 -0.04920 -0.01270 0.00100  1720 GLU A C   
4040 O  O   . GLU A 261 ? 0.30080 0.26870 0.23650 -0.04020 -0.01150 0.00880  1720 GLU A O   
4041 C  CB  . GLU A 261 ? 0.28590 0.29130 0.24160 -0.04200 -0.03270 -0.01440 1720 GLU A CB  
4042 C  CG  . GLU A 261 ? 0.30360 0.30610 0.29250 -0.03560 -0.03680 -0.01800 1720 GLU A CG  
4043 C  CD  . GLU A 261 ? 0.32170 0.32120 0.34950 -0.03220 -0.02820 -0.02110 1720 GLU A CD  
4044 O  OE1 . GLU A 261 ? 0.33150 0.32760 0.37450 -0.02650 -0.03030 -0.02880 1720 GLU A OE1 
4045 O  OE2 . GLU A 261 ? 0.32490 0.32800 0.37840 -0.03310 -0.01240 -0.01630 1720 GLU A OE2 
4052 N  N   . GLY A 262 ? 0.27760 0.25380 0.19660 -0.05620 0.01110  0.00450  1721 GLY A N   
4053 C  CA  . GLY A 262 ? 0.26490 0.24270 0.18890 -0.05890 0.02570  0.01630  1721 GLY A CA  
4054 C  C   . GLY A 262 ? 0.24990 0.23540 0.19100 -0.05470 0.01310  0.02440  1721 GLY A C   
4055 O  O   . GLY A 262 ? 0.27770 0.23670 0.22820 -0.05980 0.02220  0.03390  1721 GLY A O   
4059 N  N   . ARG A 263 ? 0.21190 0.22290 0.17060 -0.03530 -0.00360 0.03510  1722 ARG A N   
4060 C  CA  . ARG A 263 ? 0.19990 0.21140 0.16060 -0.01000 -0.01370 0.02800  1722 ARG A CA  
4061 C  C   . ARG A 263 ? 0.19220 0.20510 0.17850 0.00270  -0.01150 0.02610  1722 ARG A C   
4062 O  O   . ARG A 263 ? 0.20490 0.20790 0.22800 0.01170  -0.01230 0.02990  1722 ARG A O   
4063 C  CB  . ARG A 263 ? 0.21590 0.21690 0.17840 0.00930  -0.01210 0.01600  1722 ARG A CB  
4064 C  CG  . ARG A 263 ? 0.22890 0.22290 0.19820 0.01640  -0.02030 -0.00070 1722 ARG A CG  
4065 C  CD  . ARG A 263 ? 0.23090 0.22910 0.22810 0.02300  -0.03100 -0.00820 1722 ARG A CD  
4066 N  NE  . ARG A 263 ? 0.24310 0.23590 0.22670 0.02980  -0.03050 -0.00550 1722 ARG A NE  
4067 C  CZ  . ARG A 263 ? 0.26560 0.24440 0.21050 0.03180  -0.03600 0.00240  1722 ARG A CZ  
4068 N  NH1 . ARG A 263 ? 0.26290 0.25110 0.21160 0.03430  -0.04520 0.00290  1722 ARG A NH1 
4069 N  NH2 . ARG A 263 ? 0.27850 0.24540 0.21370 0.03460  -0.04150 0.00500  1722 ARG A NH2 
4083 N  N   . LEU A 264 ? 0.18050 0.20130 0.17080 0.01030  -0.00710 0.02510  1723 LEU A N   
4084 C  CA  . LEU A 264 ? 0.18000 0.19650 0.17100 0.00350  0.01030  0.01380  1723 LEU A CA  
4085 C  C   . LEU A 264 ? 0.16730 0.18940 0.15810 -0.00550 0.01510  0.01410  1723 LEU A C   
4086 O  O   . LEU A 264 ? 0.15060 0.19470 0.18710 -0.01200 0.00530  0.02040  1723 LEU A O   
4087 C  CB  . LEU A 264 ? 0.16980 0.19520 0.18090 0.00240  0.02050  0.00210  1723 LEU A CB  
4088 C  CG  . LEU A 264 ? 0.17830 0.19550 0.17000 0.00370  0.01560  -0.00070 1723 LEU A CG  
4089 C  CD1 . LEU A 264 ? 0.19030 0.19580 0.18230 0.00470  0.01260  0.00520  1723 LEU A CD1 
4090 C  CD2 . LEU A 264 ? 0.19060 0.19900 0.17440 0.00730  0.00850  -0.00570 1723 LEU A CD2 
4102 N  N   . SER A 265 ? 0.15840 0.17970 0.12030 -0.00420 0.01630  0.00370  1724 SER A N   
4103 C  CA  . SER A 265 ? 0.16570 0.18200 0.13960 -0.00740 0.02350  0.00700  1724 SER A CA  
4104 C  C   . SER A 265 ? 0.15520 0.17570 0.12620 -0.00990 0.01320  0.00220  1724 SER A C   
4105 O  O   . SER A 265 ? 0.15510 0.17630 0.15060 -0.00950 0.01270  0.00840  1724 SER A O   
4106 C  CB  . SER A 265 ? 0.16500 0.18360 0.14110 -0.01450 0.01800  0.00910  1724 SER A CB  
4107 O  OG  . SER A 265 ? 0.16420 0.19110 0.14880 -0.01090 -0.00550 0.01170  1724 SER A OG  
4113 N  N   . LEU A 266 ? 0.16980 0.17150 0.12340 -0.00890 0.00810  -0.00730 1725 LEU A N   
4114 C  CA  . LEU A 266 ? 0.15730 0.16340 0.12210 -0.00950 0.01610  -0.02760 1725 LEU A CA  
4115 C  C   . LEU A 266 ? 0.14990 0.15800 0.12880 -0.00740 0.02460  -0.02630 1725 LEU A C   
4116 O  O   . LEU A 266 ? 0.13950 0.15840 0.15830 -0.00410 0.02940  -0.03050 1725 LEU A O   
4117 C  CB  . LEU A 266 ? 0.18180 0.16520 0.15880 -0.00600 0.00080  -0.03270 1725 LEU A CB  
4118 C  CG  . LEU A 266 ? 0.21970 0.16660 0.18590 -0.00650 -0.00090 -0.02760 1725 LEU A CG  
4119 C  CD1 . LEU A 266 ? 0.24430 0.16720 0.20640 -0.01150 0.01610  -0.01540 1725 LEU A CD1 
4120 C  CD2 . LEU A 266 ? 0.23090 0.16800 0.20800 -0.00450 -0.01570 -0.03390 1725 LEU A CD2 
4132 N  N   . ASP A 267 ? 0.14420 0.15770 0.10410 -0.00240 0.01880  -0.01690 1726 ASP A N   
4133 C  CA  . ASP A 267 ? 0.15210 0.15840 0.10360 -0.00960 0.01060  -0.00940 1726 ASP A CA  
4134 C  C   . ASP A 267 ? 0.14620 0.14990 0.09410 -0.01700 0.00440  -0.00250 1726 ASP A C   
4135 O  O   . ASP A 267 ? 0.14310 0.14760 0.10440 -0.01120 0.01330  -0.01370 1726 ASP A O   
4136 C  CB  . ASP A 267 ? 0.16300 0.18140 0.14420 0.00180  0.01280  -0.01000 1726 ASP A CB  
4137 C  CG  . ASP A 267 ? 0.20220 0.20720 0.17610 0.00810  0.02110  -0.01700 1726 ASP A CG  
4138 O  OD1 . ASP A 267 ? 0.18930 0.22590 0.16790 0.03460  0.00030  -0.00210 1726 ASP A OD1 
4139 O  OD2 . ASP A 267 ? 0.23120 0.21460 0.21220 -0.01040 -0.00390 -0.03720 1726 ASP A OD2 
4144 N  N   . ASP A 268 ? 0.15390 0.14990 0.10900 -0.01190 0.00330  0.00720  1727 ASP A N   
4145 C  CA  . ASP A 268 ? 0.16610 0.15450 0.12710 -0.00620 0.00350  -0.00810 1727 ASP A CA  
4146 C  C   . ASP A 268 ? 0.15510 0.15360 0.11800 0.00520  -0.00460 -0.01220 1727 ASP A C   
4147 O  O   . ASP A 268 ? 0.15020 0.14950 0.12890 0.00720  0.00360  -0.01840 1727 ASP A O   
4148 C  CB  . ASP A 268 ? 0.19680 0.16580 0.15610 -0.00570 0.01920  -0.00100 1727 ASP A CB  
4149 C  CG  . ASP A 268 ? 0.21110 0.16860 0.19170 -0.00440 -0.00150 0.00720  1727 ASP A CG  
4150 O  OD1 . ASP A 268 ? 0.22990 0.17270 0.22370 -0.01080 -0.03430 0.01100  1727 ASP A OD1 
4151 O  OD2 . ASP A 268 ? 0.23580 0.17670 0.19200 0.00410  0.01140  0.01000  1727 ASP A OD2 
4156 N  N   . LEU A 269 ? 0.14020 0.16120 0.13600 -0.00640 0.00770  -0.01670 1728 LEU A N   
4157 C  CA  A LEU A 269 ? 0.15000 0.16900 0.14710 -0.01630 0.01030  -0.02020 1728 LEU A CA  
4158 C  CA  B LEU A 269 ? 0.14670 0.16630 0.13770 -0.01380 0.01280  -0.01750 1728 LEU A CA  
4159 C  C   . LEU A 269 ? 0.14070 0.17090 0.13080 -0.02490 0.02630  -0.01520 1728 LEU A C   
4160 O  O   . LEU A 269 ? 0.12750 0.19080 0.15180 -0.01940 0.00860  -0.01950 1728 LEU A O   
4161 C  CB  A LEU A 269 ? 0.15700 0.17470 0.16910 -0.02320 0.01510  -0.02200 1728 LEU A CB  
4162 C  CB  B LEU A 269 ? 0.15360 0.16690 0.14740 -0.01220 0.01420  -0.01790 1728 LEU A CB  
4163 C  CG  A LEU A 269 ? 0.16160 0.17650 0.17340 -0.03400 0.02260  -0.03080 1728 LEU A CG  
4164 C  CG  B LEU A 269 ? 0.15920 0.16480 0.14860 -0.01150 0.02060  -0.02220 1728 LEU A CG  
4165 C  CD1 A LEU A 269 ? 0.15540 0.17630 0.18410 -0.03060 0.03020  -0.03850 1728 LEU A CD1 
4166 C  CD1 B LEU A 269 ? 0.15720 0.16340 0.14610 -0.01040 0.01820  -0.02100 1728 LEU A CD1 
4167 C  CD2 A LEU A 269 ? 0.15220 0.17920 0.17860 -0.04720 0.01840  -0.02930 1728 LEU A CD2 
4168 C  CD2 B LEU A 269 ? 0.15750 0.16350 0.15320 -0.00990 0.02830  -0.02730 1728 LEU A CD2 
4191 N  N   . LEU A 270 ? 0.15450 0.15870 0.13560 -0.02930 0.01450  -0.01880 1729 LEU A N   
4192 C  CA  . LEU A 270 ? 0.16340 0.14630 0.13480 -0.02310 0.01280  -0.02510 1729 LEU A CA  
4193 C  C   . LEU A 270 ? 0.13700 0.12600 0.11940 -0.01060 0.00780  -0.01330 1729 LEU A C   
4194 O  O   . LEU A 270 ? 0.14830 0.12450 0.14230 -0.00950 0.00970  -0.00720 1729 LEU A O   
4195 C  CB  . LEU A 270 ? 0.20190 0.15690 0.15810 -0.00750 0.01070  -0.03600 1729 LEU A CB  
4196 C  CG  . LEU A 270 ? 0.22670 0.17080 0.17240 -0.01810 0.01800  -0.05150 1729 LEU A CG  
4197 C  CD1 . LEU A 270 ? 0.23540 0.17520 0.19190 -0.01400 0.00750  -0.05340 1729 LEU A CD1 
4198 C  CD2 . LEU A 270 ? 0.25180 0.17640 0.19290 -0.02580 0.01730  -0.05260 1729 LEU A CD2 
4210 N  N   . GLN A 271 ? 0.11880 0.11150 0.10650 -0.00680 0.01960  -0.00170 1730 GLN A N   
4211 C  CA  . GLN A 271 ? 0.11330 0.11210 0.11800 -0.00380 -0.00190 0.00060  1730 GLN A CA  
4212 C  C   . GLN A 271 ? 0.10720 0.11080 0.10500 -0.00170 -0.00430 -0.00930 1730 GLN A C   
4213 O  O   . GLN A 271 ? 0.12100 0.11440 0.12770 0.00290  -0.00680 -0.00240 1730 GLN A O   
4214 C  CB  . GLN A 271 ? 0.10350 0.11670 0.14890 0.00470  0.00130  0.00830  1730 GLN A CB  
4215 C  CG  . GLN A 271 ? 0.12320 0.12710 0.15540 -0.00450 -0.00520 -0.00690 1730 GLN A CG  
4216 C  CD  . GLN A 271 ? 0.12270 0.14070 0.13670 -0.00630 0.00400  -0.00860 1730 GLN A CD  
4217 O  OE1 . GLN A 271 ? 0.12320 0.15560 0.15190 0.00090  -0.00280 0.00660  1730 GLN A OE1 
4218 N  NE2 . GLN A 271 ? 0.12870 0.14530 0.13910 0.00350  0.00080  -0.00840 1730 GLN A NE2 
4227 N  N   . ARG A 272 ? 0.10130 0.11280 0.11700 -0.00310 0.00130  -0.02380 1731 ARG A N   
4228 C  CA  . ARG A 272 ? 0.10310 0.11020 0.11170 0.00730  0.01840  -0.00970 1731 ARG A CA  
4229 C  C   . ARG A 272 ? 0.10310 0.11200 0.09670 0.01440  0.00500  -0.01350 1731 ARG A C   
4230 O  O   . ARG A 272 ? 0.10250 0.11210 0.10940 0.00900  0.00170  -0.01440 1731 ARG A O   
4231 C  CB  . ARG A 272 ? 0.11690 0.10780 0.11640 0.00020  0.01490  -0.00700 1731 ARG A CB  
4232 C  CG  . ARG A 272 ? 0.12630 0.10790 0.12440 -0.00220 -0.00560 0.00200  1731 ARG A CG  
4233 C  CD  . ARG A 272 ? 0.13640 0.11390 0.11850 -0.00220 0.01070  0.01590  1731 ARG A CD  
4234 N  NE  . ARG A 272 ? 0.13830 0.11960 0.13230 0.00040  0.01090  -0.00240 1731 ARG A NE  
4235 C  CZ  . ARG A 272 ? 0.15540 0.12890 0.14850 -0.00650 0.03240  -0.01430 1731 ARG A CZ  
4236 N  NH1 . ARG A 272 ? 0.17180 0.13170 0.16260 -0.00240 0.03920  -0.02200 1731 ARG A NH1 
4237 N  NH2 . ARG A 272 ? 0.16410 0.13860 0.17730 -0.00850 0.04050  -0.01980 1731 ARG A NH2 
4251 N  N   . LEU A 273 ? 0.10410 0.11980 0.11980 0.00480  0.00790  -0.01530 1732 LEU A N   
4252 C  CA  . LEU A 273 ? 0.09500 0.11900 0.13100 0.00110  0.01100  -0.01360 1732 LEU A CA  
4253 C  C   . LEU A 273 ? 0.08670 0.11160 0.14170 -0.00950 0.01450  -0.00230 1732 LEU A C   
4254 O  O   . LEU A 273 ? 0.10010 0.11650 0.15660 -0.02250 0.00480  -0.00580 1732 LEU A O   
4255 C  CB  . LEU A 273 ? 0.11090 0.13350 0.14480 -0.00450 0.01070  -0.01480 1732 LEU A CB  
4256 C  CG  . LEU A 273 ? 0.12390 0.15520 0.17820 -0.00800 -0.01260 -0.01530 1732 LEU A CG  
4257 C  CD1 . LEU A 273 ? 0.15790 0.17010 0.19700 -0.00060 -0.03320 -0.00350 1732 LEU A CD1 
4258 C  CD2 . LEU A 273 ? 0.09930 0.16110 0.18000 0.00050  0.01370  -0.02910 1732 LEU A CD2 
4270 N  N   . HIS A 274 ? 0.09700 0.10650 0.15320 -0.01420 -0.00690 0.00150  1733 HIS A N   
4271 C  CA  . HIS A 274 ? 0.10680 0.10830 0.15030 -0.00350 -0.01870 -0.00910 1733 HIS A CA  
4272 C  C   . HIS A 274 ? 0.10540 0.11220 0.12610 -0.00650 -0.00310 -0.00440 1733 HIS A C   
4273 O  O   . HIS A 274 ? 0.11780 0.12050 0.14720 -0.00130 0.01280  -0.00400 1733 HIS A O   
4274 C  CB  . HIS A 274 ? 0.11400 0.10220 0.16040 -0.00470 -0.00780 -0.00920 1733 HIS A CB  
4275 C  CG  . HIS A 274 ? 0.11620 0.10180 0.15790 -0.00260 -0.00480 -0.00170 1733 HIS A CG  
4276 N  ND1 . HIS A 274 ? 0.12040 0.10720 0.16840 0.00340  0.00860  0.00170  1733 HIS A ND1 
4277 C  CD2 . HIS A 274 ? 0.13450 0.10290 0.17300 -0.00540 0.00670  -0.00010 1733 HIS A CD2 
4278 C  CE1 . HIS A 274 ? 0.13100 0.10670 0.17610 -0.00070 -0.00460 0.01530  1733 HIS A CE1 
4279 N  NE2 . HIS A 274 ? 0.13640 0.10850 0.18420 0.00300  -0.00760 0.00430  1733 HIS A NE2 
4287 N  N   . HIS A 275 ? 0.10700 0.10530 0.13790 -0.01180 -0.00950 -0.00760 1734 HIS A N   
4288 C  CA  . HIS A 275 ? 0.10820 0.11050 0.13960 -0.01330 -0.01360 -0.00870 1734 HIS A CA  
4289 C  C   . HIS A 275 ? 0.10770 0.11120 0.15210 -0.01040 -0.01140 -0.00750 1734 HIS A C   
4290 O  O   . HIS A 275 ? 0.11870 0.10890 0.15880 -0.00050 -0.01400 -0.01480 1734 HIS A O   
4291 C  CB  . HIS A 275 ? 0.11020 0.12130 0.14810 -0.01770 -0.01100 -0.01280 1734 HIS A CB  
4292 C  CG  . HIS A 275 ? 0.11580 0.12760 0.14910 -0.01560 0.01040  -0.01180 1734 HIS A CG  
4293 N  ND1 . HIS A 275 ? 0.11770 0.12470 0.15600 -0.01000 0.01830  -0.02510 1734 HIS A ND1 
4294 C  CD2 . HIS A 275 ? 0.13830 0.13340 0.16000 -0.02050 0.02160  -0.01400 1734 HIS A CD2 
4295 C  CE1 . HIS A 275 ? 0.14120 0.13430 0.17460 -0.01540 0.01870  -0.02570 1734 HIS A CE1 
4296 N  NE2 . HIS A 275 ? 0.14320 0.13910 0.18280 -0.01700 0.01280  -0.01270 1734 HIS A NE2 
4304 N  N   . ASN A 276 ? 0.09970 0.11240 0.14350 -0.00890 -0.01030 0.00040  1735 ASN A N   
4305 C  CA  . ASN A 276 ? 0.11550 0.10780 0.13780 -0.00770 -0.01120 0.01020  1735 ASN A CA  
4306 C  C   . ASN A 276 ? 0.10900 0.11650 0.12810 0.00870  -0.00800 0.00440  1735 ASN A C   
4307 O  O   . ASN A 276 ? 0.10830 0.12350 0.13920 0.00290  -0.01580 0.00170  1735 ASN A O   
4308 C  CB  . ASN A 276 ? 0.10900 0.10390 0.14450 -0.01490 -0.01250 0.01190  1735 ASN A CB  
4309 C  CG  . ASN A 276 ? 0.12690 0.10550 0.17250 -0.01160 -0.00370 0.01130  1735 ASN A CG  
4310 O  OD1 . ASN A 276 ? 0.15530 0.11210 0.17120 -0.00180 -0.00660 0.01250  1735 ASN A OD1 
4311 N  ND2 . ASN A 276 ? 0.09340 0.09300 0.20510 -0.00590 -0.00310 0.01500  1735 ASN A ND2 
4318 N  N   . PRO A 277 ? 0.11410 0.11660 0.11800 0.00260  -0.00830 0.00650  1736 PRO A N   
4319 C  CA  . PRO A 277 ? 0.12220 0.12430 0.14030 -0.00910 -0.00160 -0.00340 1736 PRO A CA  
4320 C  C   . PRO A 277 ? 0.12730 0.12970 0.12630 -0.01270 0.00490  -0.00440 1736 PRO A C   
4321 O  O   . PRO A 277 ? 0.12750 0.13360 0.14260 -0.01140 0.01160  -0.00380 1736 PRO A O   
4322 C  CB  . PRO A 277 ? 0.12900 0.12190 0.15960 -0.01590 0.00120  0.00530  1736 PRO A CB  
4323 C  CG  . PRO A 277 ? 0.10700 0.11810 0.14940 -0.00770 -0.01090 0.00510  1736 PRO A CG  
4324 C  CD  . PRO A 277 ? 0.10870 0.11500 0.13450 0.00360  -0.00050 0.01310  1736 PRO A CD  
4332 N  N   . ARG A 278 ? 0.13210 0.12700 0.10830 -0.01330 0.00620  -0.00400 1737 ARG A N   
4333 C  CA  . ARG A 278 ? 0.14630 0.12970 0.12490 0.00080  0.01160  0.00360  1737 ARG A CA  
4334 C  C   . ARG A 278 ? 0.13610 0.12380 0.11780 0.01060  0.01490  0.00040  1737 ARG A C   
4335 O  O   . ARG A 278 ? 0.15110 0.12180 0.12750 -0.00190 0.01480  -0.00350 1737 ARG A O   
4336 C  CB  . ARG A 278 ? 0.17240 0.13230 0.14240 0.00660  0.00800  -0.01080 1737 ARG A CB  
4337 C  CG  . ARG A 278 ? 0.15780 0.13230 0.17490 0.00370  0.01810  -0.02220 1737 ARG A CG  
4338 C  CD  . ARG A 278 ? 0.15810 0.13550 0.19450 -0.00080 0.02820  -0.03210 1737 ARG A CD  
4339 N  NE  . ARG A 278 ? 0.14550 0.14040 0.20550 0.00420  0.00980  -0.01440 1737 ARG A NE  
4340 C  CZ  . ARG A 278 ? 0.13340 0.13780 0.20550 0.01770  0.02030  -0.00800 1737 ARG A CZ  
4341 N  NH1 . ARG A 278 ? 0.13030 0.13460 0.19630 0.00550  0.01530  -0.00060 1737 ARG A NH1 
4342 N  NH2 . ARG A 278 ? 0.13720 0.14460 0.21440 0.01210  0.02630  0.00360  1737 ARG A NH2 
4356 N  N   . ARG A 279 ? 0.12080 0.12790 0.12200 0.01250  0.00160  0.00590  1738 ARG A N   
4357 C  CA  . ARG A 279 ? 0.11690 0.13730 0.10640 0.00940  -0.00950 0.01180  1738 ARG A CA  
4358 C  C   . ARG A 279 ? 0.12000 0.14400 0.10580 0.00370  -0.01490 0.01390  1738 ARG A C   
4359 O  O   . ARG A 279 ? 0.11860 0.15390 0.12270 0.00390  -0.01430 0.01430  1738 ARG A O   
4360 C  CB  . ARG A 279 ? 0.10110 0.14350 0.11700 -0.00100 0.00390  0.01440  1738 ARG A CB  
4361 C  CG  . ARG A 279 ? 0.10690 0.14850 0.13350 -0.00560 -0.01570 0.02260  1738 ARG A CG  
4362 C  CD  . ARG A 279 ? 0.11900 0.16250 0.16610 -0.00640 -0.00560 0.03690  1738 ARG A CD  
4363 N  NE  . ARG A 279 ? 0.12170 0.17500 0.22140 -0.00720 -0.02330 0.05830  1738 ARG A NE  
4364 C  CZ  . ARG A 279 ? 0.18710 0.17840 0.28240 0.00600  -0.03950 0.06840  1738 ARG A CZ  
4365 N  NH1 . ARG A 279 ? 0.18310 0.17530 0.28100 -0.00230 -0.04670 0.06220  1738 ARG A NH1 
4366 N  NH2 . ARG A 279 ? 0.22440 0.18470 0.32760 0.00770  -0.04940 0.07840  1738 ARG A NH2 
4380 N  N   . ILE A 280 ? 0.11670 0.13340 0.12300 0.00340  -0.02260 0.00740  1739 ILE A N   
4381 C  CA  . ILE A 280 ? 0.12320 0.13400 0.12500 0.00190  -0.01060 -0.00530 1739 ILE A CA  
4382 C  C   . ILE A 280 ? 0.13590 0.13080 0.13410 0.00660  -0.00650 -0.01430 1739 ILE A C   
4383 O  O   . ILE A 280 ? 0.16540 0.13120 0.17140 -0.00150 0.00690  -0.01120 1739 ILE A O   
4384 C  CB  . ILE A 280 ? 0.13370 0.13020 0.14230 0.00290  -0.01040 -0.00520 1739 ILE A CB  
4385 C  CG1 . ILE A 280 ? 0.15250 0.13020 0.16350 0.00970  -0.01330 0.00180  1739 ILE A CG1 
4386 C  CG2 . ILE A 280 ? 0.13460 0.13410 0.16030 0.00030  -0.01780 -0.01060 1739 ILE A CG2 
4387 C  CD1 . ILE A 280 ? 0.15600 0.12870 0.18390 0.01480  -0.01430 0.00200  1739 ILE A CD1 
4399 N  N   . PHE A 281 ? 0.13310 0.12590 0.13350 0.00170  0.00360  -0.00550 1740 PHE A N   
4400 C  CA  . PHE A 281 ? 0.13420 0.12990 0.13810 0.00540  0.00570  0.00210  1740 PHE A CA  
4401 C  C   . PHE A 281 ? 0.13660 0.13730 0.14540 0.00010  0.00780  0.02470  1740 PHE A C   
4402 O  O   . PHE A 281 ? 0.14980 0.14770 0.15970 0.01050  0.02230  0.03120  1740 PHE A O   
4403 C  CB  . PHE A 281 ? 0.13590 0.12240 0.14320 0.00480  0.01170  -0.00220 1740 PHE A CB  
4404 C  CG  . PHE A 281 ? 0.13600 0.12290 0.14070 0.00890  0.02100  -0.00840 1740 PHE A CG  
4405 C  CD1 . PHE A 281 ? 0.15460 0.12830 0.15800 0.03100  0.02900  0.00510  1740 PHE A CD1 
4406 C  CD2 . PHE A 281 ? 0.13600 0.13060 0.14640 0.00200  0.01420  -0.01610 1740 PHE A CD2 
4407 C  CE1 . PHE A 281 ? 0.16950 0.13550 0.17500 0.03120  0.02830  -0.00410 1740 PHE A CE1 
4408 C  CE2 . PHE A 281 ? 0.14180 0.13580 0.15230 0.00340  0.00200  0.00070  1740 PHE A CE2 
4409 C  CZ  . PHE A 281 ? 0.16460 0.13750 0.15700 0.01900  0.00640  -0.00620 1740 PHE A CZ  
4419 N  N   . HIS A 282 ? 0.13390 0.13340 0.14510 -0.00260 0.01920  0.02590  1741 HIS A N   
4420 C  CA  . HIS A 282 ? 0.12290 0.13880 0.13250 -0.00130 0.01210  0.03060  1741 HIS A CA  
4421 C  C   . HIS A 282 ? 0.13040 0.13650 0.13340 0.00120  0.01190  0.02590  1741 HIS A C   
4422 O  O   . HIS A 282 ? 0.15500 0.14650 0.14790 0.00270  0.00180  0.02180  1741 HIS A O   
4423 C  CB  . HIS A 282 ? 0.14190 0.15530 0.15680 0.00600  -0.00400 0.04430  1741 HIS A CB  
4424 C  CG  . HIS A 282 ? 0.18930 0.17350 0.20640 -0.00510 -0.01150 0.05040  1741 HIS A CG  
4425 N  ND1 . HIS A 282 ? 0.22000 0.17970 0.25160 -0.02290 -0.01920 0.04120  1741 HIS A ND1 
4426 C  CD2 . HIS A 282 ? 0.19540 0.18080 0.22470 -0.01210 0.01140  0.04810  1741 HIS A CD2 
4427 C  CE1 . HIS A 282 ? 0.23440 0.18200 0.27890 -0.01970 -0.01210 0.04140  1741 HIS A CE1 
4428 N  NE2 . HIS A 282 ? 0.23170 0.18240 0.26130 -0.01460 -0.00210 0.04180  1741 HIS A NE2 
4436 N  N   . LEU A 283 ? 0.13660 0.13180 0.15410 -0.00670 0.01300  0.01720  1742 LEU A N   
4437 C  CA  . LEU A 283 ? 0.14310 0.13210 0.16830 -0.01430 0.00320  0.01580  1742 LEU A CA  
4438 C  C   . LEU A 283 ? 0.14470 0.13980 0.18100 -0.01260 0.01310  0.00580  1742 LEU A C   
4439 O  O   . LEU A 283 ? 0.14360 0.14340 0.20400 -0.01080 0.03520  0.00400  1742 LEU A O   
4440 C  CB  . LEU A 283 ? 0.14940 0.13150 0.17960 -0.01290 0.00040  0.01770  1742 LEU A CB  
4441 C  CG  . LEU A 283 ? 0.14830 0.13030 0.18960 -0.00260 -0.00880 0.02140  1742 LEU A CG  
4442 C  CD1 . LEU A 283 ? 0.14330 0.13100 0.19630 -0.00380 -0.00910 0.02100  1742 LEU A CD1 
4443 C  CD2 . LEU A 283 ? 0.15090 0.13590 0.20060 -0.00170 0.00280  0.01500  1742 LEU A CD2 
4455 N  N   . PRO A 284 ? 0.13980 0.13600 0.17720 -0.00230 0.00830  0.00980  1743 PRO A N   
4456 C  CA  . PRO A 284 ? 0.13050 0.13310 0.18400 -0.00320 0.01550  0.00560  1743 PRO A CA  
4457 C  C   . PRO A 284 ? 0.11720 0.13080 0.18940 -0.00140 0.02850  -0.00610 1743 PRO A C   
4458 O  O   . PRO A 284 ? 0.12790 0.13580 0.19650 0.00220  0.01270  -0.00670 1743 PRO A O   
4459 C  CB  . PRO A 284 ? 0.14000 0.13170 0.18240 0.00890  -0.00320 0.00870  1743 PRO A CB  
4460 C  CG  . PRO A 284 ? 0.15730 0.12980 0.18060 0.00170  0.01490  0.00380  1743 PRO A CG  
4461 C  CD  . PRO A 284 ? 0.15450 0.13080 0.17920 0.00450  0.01420  0.01500  1743 PRO A CD  
4469 N  N   . PRO A 285 ? 0.11330 0.13610 0.20350 -0.00030 0.02870  -0.02220 1744 PRO A N   
4470 C  CA  . PRO A 285 ? 0.12070 0.13690 0.19580 0.00010  0.02000  -0.01660 1744 PRO A CA  
4471 C  C   . PRO A 285 ? 0.12370 0.13200 0.19460 -0.00630 0.01040  -0.00650 1744 PRO A C   
4472 O  O   . PRO A 285 ? 0.14730 0.14260 0.22440 -0.01460 0.00640  -0.00810 1744 PRO A O   
4473 C  CB  . PRO A 285 ? 0.13060 0.14790 0.20870 -0.00760 0.02260  -0.03220 1744 PRO A CB  
4474 C  CG  . PRO A 285 ? 0.13620 0.15740 0.22930 -0.00820 0.01850  -0.04240 1744 PRO A CG  
4475 C  CD  . PRO A 285 ? 0.11880 0.14800 0.20080 -0.01040 0.03750  -0.03610 1744 PRO A CD  
4483 N  N   . GLN A 286 ? 0.13100 0.12750 0.19760 -0.00750 0.00160  -0.00730 1745 GLN A N   
4484 C  CA  . GLN A 286 ? 0.13770 0.13260 0.18870 -0.00240 0.00180  -0.01040 1745 GLN A CA  
4485 C  C   . GLN A 286 ? 0.14660 0.14390 0.19670 0.00760  -0.00550 -0.02070 1745 GLN A C   
4486 O  O   . GLN A 286 ? 0.15310 0.13540 0.20990 0.00170  0.01620  -0.02800 1745 GLN A O   
4487 C  CB  . GLN A 286 ? 0.13200 0.12830 0.18820 -0.00090 0.01010  -0.01000 1745 GLN A CB  
4488 C  CG  . GLN A 286 ? 0.13810 0.12310 0.18380 -0.00460 0.01180  -0.00630 1745 GLN A CG  
4489 C  CD  . GLN A 286 ? 0.14140 0.12180 0.17800 -0.01490 0.00390  0.00900  1745 GLN A CD  
4490 O  OE1 . GLN A 286 ? 0.14380 0.12940 0.18470 -0.01790 0.01170  0.01590  1745 GLN A OE1 
4491 N  NE2 . GLN A 286 ? 0.14600 0.11240 0.17410 -0.01480 0.00320  0.01640  1745 GLN A NE2 
4500 N  N   . GLU A 287 ? 0.15290 0.15560 0.20280 0.01250  -0.00770 -0.02440 1746 GLU A N   
4501 C  CA  . GLU A 287 ? 0.19170 0.16900 0.21810 0.02330  -0.00620 -0.02310 1746 GLU A CA  
4502 C  C   . GLU A 287 ? 0.17040 0.14200 0.20910 0.01740  0.00570  -0.01920 1746 GLU A C   
4503 O  O   . GLU A 287 ? 0.15490 0.12200 0.21390 0.00310  0.01070  -0.01200 1746 GLU A O   
4504 C  CB  . GLU A 287 ? 0.25620 0.20980 0.27250 0.03570  -0.01130 -0.02650 1746 GLU A CB  
4507 N  N   . ASP A 288 ? 0.16930 0.14740 0.21270 0.01560  0.00780  -0.01600 1747 ASP A N   
4508 C  CA  A ASP A 288 ? 0.17190 0.15360 0.21290 0.01450  0.01940  -0.02210 1747 ASP A CA  
4509 C  CA  B ASP A 288 ? 0.17900 0.15860 0.23150 0.01250  0.02300  -0.01720 1747 ASP A CA  
4510 C  C   . ASP A 288 ? 0.16300 0.15310 0.22530 0.01020  0.03300  -0.02300 1747 ASP A C   
4511 O  O   . ASP A 288 ? 0.16710 0.14910 0.24170 0.00550  0.02440  -0.03260 1747 ASP A O   
4512 C  CB  A ASP A 288 ? 0.18830 0.16130 0.19960 0.01760  0.01750  -0.02790 1747 ASP A CB  
4513 C  CB  B ASP A 288 ? 0.20520 0.17490 0.25620 0.01240  0.02600  -0.01300 1747 ASP A CB  
4514 C  CG  A ASP A 288 ? 0.20800 0.16740 0.19550 0.01950  0.02260  -0.03360 1747 ASP A CG  
4515 C  CG  B ASP A 288 ? 0.22450 0.18800 0.28020 0.00910  0.03430  -0.00860 1747 ASP A CG  
4516 O  OD1 A ASP A 288 ? 0.22910 0.17260 0.22080 0.02350  -0.00090 -0.03840 1747 ASP A OD1 
4517 O  OD1 B ASP A 288 ? 0.22830 0.19210 0.28430 0.00680  0.04940  -0.01540 1747 ASP A OD1 
4518 O  OD2 A ASP A 288 ? 0.20530 0.16990 0.20160 0.02130  0.03210  -0.03740 1747 ASP A OD2 
4519 O  OD2 B ASP A 288 ? 0.22430 0.19350 0.29800 0.00980  0.03220  0.00110  1747 ASP A OD2 
4528 N  N   . THR A 289 ? 0.14300 0.14980 0.21870 0.00260  0.04190  -0.02330 1748 THR A N   
4529 C  CA  . THR A 289 ? 0.14620 0.14790 0.21320 0.00080  0.02620  -0.01370 1748 THR A CA  
4530 C  C   . THR A 289 ? 0.14670 0.14980 0.20820 -0.00930 0.02230  -0.01180 1748 THR A C   
4531 O  O   . THR A 289 ? 0.15370 0.15330 0.21810 -0.01470 0.00160  0.00250  1748 THR A O   
4532 C  CB  . THR A 289 ? 0.14730 0.13840 0.20410 0.00620  0.02010  -0.00480 1748 THR A CB  
4533 O  OG1 . THR A 289 ? 0.15080 0.12880 0.20540 0.00730  0.03140  -0.00620 1748 THR A OG1 
4534 C  CG2 . THR A 289 ? 0.13680 0.14220 0.20270 0.00660  0.01530  -0.01230 1748 THR A CG2 
4542 N  N   . TYR A 290 ? 0.16220 0.14990 0.18820 -0.01280 0.03270  -0.01750 1749 TYR A N   
4543 C  CA  . TYR A 290 ? 0.16130 0.15430 0.18980 -0.01300 0.04380  -0.01480 1749 TYR A CA  
4544 C  C   . TYR A 290 ? 0.14790 0.14920 0.18350 -0.02990 0.02700  -0.00730 1749 TYR A C   
4545 O  O   . TYR A 290 ? 0.16360 0.14250 0.20350 -0.04040 0.03350  -0.01470 1749 TYR A O   
4546 C  CB  . TYR A 290 ? 0.19120 0.16610 0.21190 -0.01400 0.05940  -0.02990 1749 TYR A CB  
4547 C  CG  . TYR A 290 ? 0.22860 0.18000 0.23890 -0.01420 0.06810  -0.03810 1749 TYR A CG  
4548 C  CD1 . TYR A 290 ? 0.24530 0.18730 0.27590 -0.00940 0.08140  -0.03680 1749 TYR A CD1 
4549 C  CD2 . TYR A 290 ? 0.25820 0.18830 0.25430 -0.02050 0.06250  -0.05320 1749 TYR A CD2 
4550 C  CE1 . TYR A 290 ? 0.27220 0.19500 0.29870 -0.01200 0.08990  -0.04750 1749 TYR A CE1 
4551 C  CE2 . TYR A 290 ? 0.28410 0.19660 0.28940 -0.02190 0.07330  -0.06180 1749 TYR A CE2 
4552 C  CZ  . TYR A 290 ? 0.29570 0.19620 0.30520 -0.02010 0.08690  -0.06610 1749 TYR A CZ  
4553 O  OH  . TYR A 290 ? 0.33110 0.20390 0.35110 -0.02400 0.09430  -0.07540 1749 TYR A OH  
4563 N  N   . VAL A 291 ? 0.14150 0.15730 0.17280 -0.01920 0.02400  -0.00500 1750 VAL A N   
4564 C  CA  . VAL A 291 ? 0.14930 0.16710 0.17050 -0.02900 0.02860  -0.01810 1750 VAL A CA  
4565 C  C   . VAL A 291 ? 0.16890 0.18070 0.17970 -0.04320 0.02640  -0.01460 1750 VAL A C   
4566 O  O   . VAL A 291 ? 0.18850 0.19390 0.19450 -0.05590 0.01490  0.00320  1750 VAL A O   
4567 C  CB  . VAL A 291 ? 0.16230 0.16890 0.19270 -0.01380 0.01260  -0.02960 1750 VAL A CB  
4568 C  CG1 . VAL A 291 ? 0.18940 0.17120 0.21020 -0.00180 0.00450  -0.01810 1750 VAL A CG1 
4569 C  CG2 . VAL A 291 ? 0.14920 0.17090 0.20640 -0.00990 0.00130  -0.04330 1750 VAL A CG2 
4579 N  N   . GLU A 292 ? 0.16730 0.18080 0.18680 -0.04090 0.02170  -0.03440 1751 GLU A N   
4580 C  CA  . GLU A 292 ? 0.17240 0.19040 0.20510 -0.03320 0.02480  -0.04380 1751 GLU A CA  
4581 C  C   . GLU A 292 ? 0.16550 0.18450 0.18620 -0.03230 0.01530  -0.03590 1751 GLU A C   
4582 O  O   . GLU A 292 ? 0.17880 0.18210 0.18120 -0.04160 0.01520  -0.03260 1751 GLU A O   
4583 C  CB  . GLU A 292 ? 0.20210 0.20830 0.24030 -0.02420 0.00920  -0.06500 1751 GLU A CB  
4584 C  CG  . GLU A 292 ? 0.24230 0.22470 0.29550 -0.01600 -0.00560 -0.07380 1751 GLU A CG  
4585 C  CD  . GLU A 292 ? 0.27620 0.24390 0.35950 -0.00330 -0.00790 -0.07370 1751 GLU A CD  
4586 O  OE1 . GLU A 292 ? 0.29340 0.25050 0.38500 -0.00950 0.00150  -0.05850 1751 GLU A OE1 
4587 O  OE2 . GLU A 292 ? 0.29500 0.25670 0.39570 0.00640  -0.00470 -0.07620 1751 GLU A OE2 
4594 N  N   . VAL A 293 ? 0.16590 0.18800 0.19460 -0.01880 0.02200  -0.02790 1752 VAL A N   
4595 C  CA  . VAL A 293 ? 0.17650 0.18980 0.18720 -0.01770 0.01970  -0.03150 1752 VAL A CA  
4596 C  C   . VAL A 293 ? 0.18370 0.19800 0.17760 -0.01220 0.02370  -0.03650 1752 VAL A C   
4597 O  O   . VAL A 293 ? 0.18870 0.19940 0.17960 -0.00240 0.02970  -0.02620 1752 VAL A O   
4598 C  CB  . VAL A 293 ? 0.18640 0.18920 0.20710 -0.02710 0.00510  -0.03510 1752 VAL A CB  
4599 C  CG1 . VAL A 293 ? 0.18570 0.18800 0.22710 -0.02620 -0.00510 -0.04220 1752 VAL A CG1 
4600 C  CG2 . VAL A 293 ? 0.20630 0.19490 0.22930 -0.02190 -0.00790 -0.02740 1752 VAL A CG2 
4610 N  N   . ASP A 294 ? 0.18700 0.21310 0.16420 -0.01520 0.02100  -0.04190 1753 ASP A N   
4611 C  CA  . ASP A 294 ? 0.21260 0.23520 0.17350 -0.01960 0.02150  -0.06160 1753 ASP A CA  
4612 C  C   . ASP A 294 ? 0.21560 0.24210 0.17430 -0.01960 0.02720  -0.05140 1753 ASP A C   
4613 O  O   . ASP A 294 ? 0.20570 0.23750 0.18510 -0.01350 0.03440  -0.04960 1753 ASP A O   
4614 C  CB  . ASP A 294 ? 0.24780 0.25590 0.21000 -0.03090 0.00970  -0.07710 1753 ASP A CB  
4615 C  CG  . ASP A 294 ? 0.29150 0.27920 0.24650 -0.04620 -0.01760 -0.09690 1753 ASP A CG  
4616 O  OD1 . ASP A 294 ? 0.32090 0.30770 0.26160 -0.05180 -0.02600 -0.09880 1753 ASP A OD1 
4617 O  OD2 . ASP A 294 ? 0.31370 0.27670 0.26400 -0.03570 -0.03200 -0.09630 1753 ASP A OD2 
4622 N  N   . LEU A 295 ? 0.23380 0.25540 0.18740 -0.01660 0.03640  -0.03760 1754 LEU A N   
4623 C  CA  . LEU A 295 ? 0.26050 0.27450 0.22010 -0.01440 0.02580  -0.02820 1754 LEU A CA  
4624 C  C   . LEU A 295 ? 0.26660 0.29700 0.25590 -0.00630 0.02940  -0.02130 1754 LEU A C   
4625 O  O   . LEU A 295 ? 0.26730 0.29800 0.28560 0.00480  0.02460  -0.01340 1754 LEU A O   
4626 C  CB  . LEU A 295 ? 0.28180 0.27680 0.24190 -0.01670 0.00800  -0.02300 1754 LEU A CB  
4627 C  CG  . LEU A 295 ? 0.30530 0.28020 0.26500 -0.01160 0.00060  -0.02420 1754 LEU A CG  
4628 C  CD1 . LEU A 295 ? 0.31750 0.28110 0.29570 -0.01710 -0.01070 -0.02130 1754 LEU A CD1 
4629 C  CD2 . LEU A 295 ? 0.32710 0.28090 0.27090 -0.00220 -0.01210 -0.03550 1754 LEU A CD2 
4641 N  N   . GLU A 296 ? 0.28440 0.32090 0.25500 0.00740  0.03370  -0.02370 1755 GLU A N   
4642 C  CA  . GLU A 296 ? 0.31120 0.34530 0.29010 0.00900  0.00700  -0.02610 1755 GLU A CA  
4643 C  C   . GLU A 296 ? 0.30120 0.34330 0.27740 0.00540  -0.00200 -0.04430 1755 GLU A C   
4644 O  O   . GLU A 296 ? 0.30020 0.34860 0.29210 0.00520  -0.02530 -0.04230 1755 GLU A O   
4645 C  CB  . GLU A 296 ? 0.34950 0.37060 0.35180 0.01160  -0.00880 -0.01430 1755 GLU A CB  
4646 C  CG  . GLU A 296 ? 0.39480 0.39410 0.40280 0.01130  -0.00740 -0.00610 1755 GLU A CG  
4647 C  CD  . GLU A 296 ? 0.43180 0.41480 0.44070 0.01100  -0.00770 0.00100  1755 GLU A CD  
4648 O  OE1 . GLU A 296 ? 0.44670 0.42340 0.45470 0.01770  -0.00740 0.00480  1755 GLU A OE1 
4649 O  OE2 . GLU A 296 ? 0.44430 0.42130 0.45560 0.00520  -0.00720 0.00210  1755 GLU A OE2 
4656 N  N   . HIS A 297 ? 0.29050 0.33780 0.26620 -0.00580 0.01150  -0.06650 1756 HIS A N   
4657 C  CA  . HIS A 297 ? 0.27830 0.33460 0.27530 -0.01570 0.00890  -0.07490 1756 HIS A CA  
4658 C  C   . HIS A 297 ? 0.25660 0.32830 0.23480 -0.01360 -0.00130 -0.07460 1756 HIS A C   
4659 O  O   . HIS A 297 ? 0.24080 0.32500 0.21190 -0.00760 -0.01480 -0.07350 1756 HIS A O   
4660 C  CB  . HIS A 297 ? 0.28980 0.33870 0.31060 -0.03370 0.00810  -0.07710 1756 HIS A CB  
4661 C  CG  . HIS A 297 ? 0.30150 0.34500 0.34050 -0.05420 0.00400  -0.07800 1756 HIS A CG  
4662 N  ND1 . HIS A 297 ? 0.31610 0.34920 0.35550 -0.05930 0.00200  -0.07620 1756 HIS A ND1 
4663 C  CD2 . HIS A 297 ? 0.29490 0.34800 0.35290 -0.06460 0.01290  -0.07730 1756 HIS A CD2 
4664 C  CE1 . HIS A 297 ? 0.30430 0.35010 0.35320 -0.06580 0.01090  -0.07410 1756 HIS A CE1 
4665 N  NE2 . HIS A 297 ? 0.29590 0.35000 0.35970 -0.06650 0.01990  -0.07510 1756 HIS A NE2 
4673 N  N   . GLU A 298 ? 0.25830 0.33020 0.23930 -0.02480 -0.00230 -0.06480 1757 GLU A N   
4674 C  CA  . GLU A 298 ? 0.25830 0.33300 0.25250 -0.03370 -0.00760 -0.04960 1757 GLU A CA  
4675 C  C   . GLU A 298 ? 0.22950 0.31950 0.21760 -0.03640 -0.02150 -0.05660 1757 GLU A C   
4676 O  O   . GLU A 298 ? 0.23830 0.32400 0.24040 -0.04730 -0.02290 -0.06720 1757 GLU A O   
4677 C  CB  . GLU A 298 ? 0.30150 0.35180 0.31180 -0.03810 -0.00330 -0.02870 1757 GLU A CB  
4678 C  CG  . GLU A 298 ? 0.36570 0.37110 0.36050 -0.03760 0.00040  -0.01320 1757 GLU A CG  
4679 C  CD  . GLU A 298 ? 0.43790 0.38860 0.41290 -0.03970 -0.01020 0.00150  1757 GLU A CD  
4680 O  OE1 . GLU A 298 ? 0.46280 0.39590 0.43490 -0.04160 -0.01270 0.00860  1757 GLU A OE1 
4681 O  OE2 . GLU A 298 ? 0.46690 0.39700 0.43900 -0.03400 -0.01210 0.00530  1757 GLU A OE2 
4688 N  N   . TRP A 299 ? 0.19400 0.30160 0.18500 -0.02380 -0.02330 -0.04720 1758 TRP A N   
4689 C  CA  . TRP A 299 ? 0.18060 0.28390 0.17390 -0.02740 -0.02750 -0.04890 1758 TRP A CA  
4690 C  C   . TRP A 299 ? 0.16690 0.27910 0.18080 -0.02750 -0.03520 -0.05060 1758 TRP A C   
4691 O  O   . TRP A 299 ? 0.17600 0.27430 0.21220 -0.02620 -0.01630 -0.05470 1758 TRP A O   
4692 C  CB  . TRP A 299 ? 0.17850 0.27480 0.17240 -0.01870 -0.02670 -0.04760 1758 TRP A CB  
4693 C  CG  . TRP A 299 ? 0.17340 0.26570 0.15990 -0.01780 -0.01460 -0.04360 1758 TRP A CG  
4694 C  CD1 . TRP A 299 ? 0.18460 0.26400 0.17110 -0.02020 -0.02330 -0.04730 1758 TRP A CD1 
4695 C  CD2 . TRP A 299 ? 0.17050 0.26510 0.15630 -0.02790 -0.01530 -0.03370 1758 TRP A CD2 
4696 N  NE1 . TRP A 299 ? 0.18830 0.26460 0.17530 -0.02260 -0.01910 -0.03510 1758 TRP A NE1 
4697 C  CE2 . TRP A 299 ? 0.17590 0.26340 0.17740 -0.03560 -0.00640 -0.03290 1758 TRP A CE2 
4698 C  CE3 . TRP A 299 ? 0.16590 0.26880 0.15530 -0.03440 -0.02680 -0.03090 1758 TRP A CE3 
4699 C  CZ2 . TRP A 299 ? 0.17010 0.26470 0.18920 -0.04830 0.00560  -0.02150 1758 TRP A CZ2 
4700 C  CZ3 . TRP A 299 ? 0.17280 0.27010 0.18120 -0.03670 -0.03530 -0.02630 1758 TRP A CZ3 
4701 C  CH2 . TRP A 299 ? 0.16930 0.26790 0.19030 -0.04430 -0.02610 -0.02710 1758 TRP A CH2 
4712 N  N   . THR A 300 ? 0.18680 0.28140 0.16110 -0.02330 -0.02270 -0.03590 1759 THR A N   
4713 C  CA  . THR A 300 ? 0.19710 0.28100 0.15410 -0.01860 -0.03100 -0.02010 1759 THR A CA  
4714 C  C   . THR A 300 ? 0.19000 0.26570 0.15260 -0.02060 -0.03060 -0.02340 1759 THR A C   
4715 O  O   . THR A 300 ? 0.19290 0.26660 0.16860 -0.03300 -0.01140 -0.01920 1759 THR A O   
4716 C  CB  . THR A 300 ? 0.22360 0.29680 0.16880 -0.00860 -0.02140 -0.01270 1759 THR A CB  
4717 O  OG1 . THR A 300 ? 0.24910 0.30640 0.17440 -0.00160 -0.02120 -0.01370 1759 THR A OG1 
4718 C  CG2 . THR A 300 ? 0.22540 0.30180 0.18580 0.00670  -0.01830 -0.01050 1759 THR A CG2 
4726 N  N   . ILE A 301 ? 0.16770 0.24770 0.16750 -0.01360 -0.02300 -0.02730 1760 ILE A N   
4727 C  CA  A ILE A 301 ? 0.15880 0.24140 0.17120 -0.00840 -0.02040 -0.02660 1760 ILE A CA  
4728 C  CA  B ILE A 301 ? 0.16510 0.24220 0.17520 -0.00590 -0.01960 -0.02560 1760 ILE A CA  
4729 C  C   . ILE A 301 ? 0.15630 0.24180 0.18100 -0.00510 -0.02320 -0.02560 1760 ILE A C   
4730 O  O   . ILE A 301 ? 0.14830 0.24010 0.19250 0.00250  -0.01430 -0.02540 1760 ILE A O   
4731 C  CB  A ILE A 301 ? 0.14450 0.23890 0.15590 -0.00800 -0.00610 -0.02270 1760 ILE A CB  
4732 C  CB  B ILE A 301 ? 0.16610 0.23960 0.17270 -0.00170 -0.01150 -0.02310 1760 ILE A CB  
4733 C  CG1 A ILE A 301 ? 0.14620 0.23800 0.16050 -0.01310 0.00320  -0.01700 1760 ILE A CG1 
4734 C  CG1 B ILE A 301 ? 0.17120 0.23860 0.17400 0.00240  -0.01040 -0.01910 1760 ILE A CG1 
4735 C  CG2 A ILE A 301 ? 0.13800 0.23810 0.15540 -0.00860 0.00230  -0.02120 1760 ILE A CG2 
4736 C  CG2 B ILE A 301 ? 0.16460 0.23850 0.17410 -0.00330 -0.00680 -0.02170 1760 ILE A CG2 
4737 C  CD1 A ILE A 301 ? 0.13610 0.23660 0.15930 -0.01730 0.00830  -0.01970 1760 ILE A CD1 
4738 C  CD1 B ILE A 301 ? 0.16980 0.23780 0.16990 0.00540  -0.00580 -0.01830 1760 ILE A CD1 
4761 N  N   . PRO A 302 ? 0.15220 0.24510 0.18770 -0.00830 -0.02250 -0.02470 1761 PRO A N   
4762 C  CA  . PRO A 302 ? 0.15210 0.25160 0.20870 -0.02010 -0.01290 -0.02320 1761 PRO A CA  
4763 C  C   . PRO A 302 ? 0.13080 0.25960 0.20300 -0.02260 -0.01390 -0.01740 1761 PRO A C   
4764 O  O   . PRO A 302 ? 0.13820 0.25780 0.19080 -0.01630 -0.01110 -0.02250 1761 PRO A O   
4765 C  CB  . PRO A 302 ? 0.16740 0.25080 0.21570 -0.02500 -0.00120 -0.02850 1761 PRO A CB  
4766 C  CG  . PRO A 302 ? 0.18350 0.24970 0.20910 -0.02480 -0.00470 -0.02720 1761 PRO A CG  
4767 C  CD  . PRO A 302 ? 0.17420 0.24580 0.20210 -0.01790 -0.02100 -0.02930 1761 PRO A CD  
4775 N  N   . SER A 303 ? 0.11850 0.26610 0.20490 -0.02710 -0.01500 -0.00890 1762 SER A N   
4776 C  CA  . SER A 303 ? 0.12930 0.27270 0.20460 -0.02020 -0.01990 -0.00900 1762 SER A CA  
4777 C  C   . SER A 303 ? 0.14100 0.26710 0.18170 -0.01340 -0.01800 -0.00700 1762 SER A C   
4778 O  O   . SER A 303 ? 0.15080 0.27310 0.18470 -0.00800 -0.02370 0.00290  1762 SER A O   
4779 C  CB  . SER A 303 ? 0.14580 0.28440 0.24210 -0.01850 -0.01950 -0.01040 1762 SER A CB  
4780 O  OG  . SER A 303 ? 0.17080 0.29560 0.25930 -0.01760 -0.02510 -0.01240 1762 SER A OG  
4786 N  N   . HIS A 304 ? 0.13660 0.25720 0.17910 -0.01280 -0.03110 -0.01080 1763 HIS A N   
4787 C  CA  . HIS A 304 ? 0.14350 0.24500 0.19860 -0.01720 -0.02670 -0.01520 1763 HIS A CA  
4788 C  C   . HIS A 304 ? 0.14430 0.23540 0.19190 -0.02330 -0.03130 -0.03440 1763 HIS A C   
4789 O  O   . HIS A 304 ? 0.15240 0.23780 0.19030 -0.02380 -0.03690 -0.04440 1763 HIS A O   
4790 C  CB  . HIS A 304 ? 0.16670 0.24230 0.22770 -0.02720 -0.02510 -0.00880 1763 HIS A CB  
4791 C  CG  . HIS A 304 ? 0.17310 0.24140 0.25840 -0.03010 -0.01850 -0.00550 1763 HIS A CG  
4792 N  ND1 . HIS A 304 ? 0.18510 0.24210 0.25910 -0.02620 -0.02140 -0.00550 1763 HIS A ND1 
4793 C  CD2 . HIS A 304 ? 0.17890 0.24210 0.28080 -0.03530 -0.01630 -0.00240 1763 HIS A CD2 
4794 C  CE1 . HIS A 304 ? 0.18540 0.24200 0.27380 -0.03570 -0.02270 -0.00630 1763 HIS A CE1 
4795 N  NE2 . HIS A 304 ? 0.19660 0.24240 0.29220 -0.03530 -0.02030 -0.00710 1763 HIS A NE2 
4803 N  N   . MET A 305 ? 0.13600 0.22550 0.19850 -0.01880 -0.03090 -0.03210 1764 MET A N   
4804 C  CA  . MET A 305 ? 0.12290 0.22090 0.20210 -0.02410 -0.01980 -0.02240 1764 MET A CA  
4805 C  C   . MET A 305 ? 0.13420 0.21140 0.20360 -0.01570 -0.01250 -0.03170 1764 MET A C   
4806 O  O   . MET A 305 ? 0.13800 0.20820 0.21550 -0.00140 -0.01370 -0.03190 1764 MET A O   
4807 C  CB  . MET A 305 ? 0.12650 0.23100 0.20710 -0.02740 -0.02350 -0.00650 1764 MET A CB  
4808 C  CG  . MET A 305 ? 0.15300 0.25130 0.23440 -0.03500 -0.03270 0.01860  1764 MET A CG  
4809 S  SD  . MET A 305 ? 0.18450 0.27320 0.26670 -0.05270 -0.06300 0.04920  1764 MET A SD  
4810 C  CE  . MET A 305 ? 0.19830 0.27750 0.25410 -0.04510 -0.06190 0.05080  1764 MET A CE  
4820 N  N   . PRO A 306 ? 0.15460 0.20680 0.19730 -0.01640 -0.01160 -0.03980 1765 PRO A N   
4821 C  CA  . PRO A 306 ? 0.16480 0.20450 0.20540 -0.01990 -0.00510 -0.03420 1765 PRO A CA  
4822 C  C   . PRO A 306 ? 0.16310 0.19810 0.22570 -0.02780 -0.01800 -0.01700 1765 PRO A C   
4823 O  O   . PRO A 306 ? 0.17160 0.20720 0.26650 -0.04120 -0.02590 -0.00460 1765 PRO A O   
4824 C  CB  . PRO A 306 ? 0.19850 0.20690 0.20270 -0.01790 0.00440  -0.04610 1765 PRO A CB  
4825 C  CG  . PRO A 306 ? 0.21050 0.20810 0.19990 -0.01660 -0.00410 -0.04950 1765 PRO A CG  
4826 C  CD  . PRO A 306 ? 0.18310 0.20710 0.19510 -0.01610 -0.01680 -0.05420 1765 PRO A CD  
4834 N  N   . PHE A 307 ? 0.15050 0.18360 0.20740 -0.02460 -0.01810 -0.02720 1766 PHE A N   
4835 C  CA  . PHE A 307 ? 0.13560 0.17040 0.18960 -0.02240 -0.01260 -0.02500 1766 PHE A CA  
4836 C  C   . PHE A 307 ? 0.14490 0.17140 0.19050 -0.02550 -0.00200 -0.01800 1766 PHE A C   
4837 O  O   . PHE A 307 ? 0.16520 0.17250 0.21110 -0.03160 0.00020  -0.00930 1766 PHE A O   
4838 C  CB  . PHE A 307 ? 0.14290 0.16740 0.19800 -0.00770 -0.01230 -0.03410 1766 PHE A CB  
4839 C  CG  . PHE A 307 ? 0.16760 0.16730 0.21400 -0.00920 -0.00010 -0.04280 1766 PHE A CG  
4840 C  CD1 . PHE A 307 ? 0.19860 0.17220 0.23230 -0.00950 0.01620  -0.04820 1766 PHE A CD1 
4841 C  CD2 . PHE A 307 ? 0.17190 0.16980 0.23600 -0.01310 0.02260  -0.04220 1766 PHE A CD2 
4842 C  CE1 . PHE A 307 ? 0.22710 0.17550 0.23910 -0.01510 0.02840  -0.05400 1766 PHE A CE1 
4843 C  CE2 . PHE A 307 ? 0.19650 0.17650 0.24960 -0.01520 0.03520  -0.04660 1766 PHE A CE2 
4844 C  CZ  . PHE A 307 ? 0.22320 0.17820 0.24420 -0.01750 0.03320  -0.05260 1766 PHE A CZ  
4854 N  N   . SER A 308 ? 0.13820 0.17120 0.17170 -0.02460 -0.00550 -0.01950 1767 SER A N   
4855 C  CA  . SER A 308 ? 0.12750 0.17180 0.15570 -0.02600 -0.00630 -0.01790 1767 SER A CA  
4856 C  C   . SER A 308 ? 0.12390 0.17490 0.16370 -0.02540 -0.00980 -0.01380 1767 SER A C   
4857 O  O   . SER A 308 ? 0.12750 0.17550 0.17390 -0.01730 -0.01450 -0.00480 1767 SER A O   
4858 C  CB  . SER A 308 ? 0.13460 0.17370 0.15980 -0.02680 -0.01580 -0.01000 1767 SER A CB  
4859 O  OG  . SER A 308 ? 0.12520 0.17420 0.17030 -0.02880 0.00160  -0.00100 1767 SER A OG  
4865 N  N   . LYS A 309 ? 0.11200 0.18170 0.18060 -0.02680 -0.00190 -0.01070 1768 LYS A N   
4866 C  CA  . LYS A 309 ? 0.12410 0.19370 0.20750 -0.03290 0.01030  -0.00810 1768 LYS A CA  
4867 C  C   . LYS A 309 ? 0.11820 0.19850 0.21260 -0.02360 0.00750  -0.00910 1768 LYS A C   
4868 O  O   . LYS A 309 ? 0.12560 0.21150 0.24550 -0.01030 0.00140  -0.00020 1768 LYS A O   
4869 C  CB  . LYS A 309 ? 0.13720 0.19940 0.21630 -0.03520 -0.00100 0.00440  1768 LYS A CB  
4870 C  CG  . LYS A 309 ? 0.15660 0.21110 0.22100 -0.03460 -0.00020 0.01480  1768 LYS A CG  
4871 C  CD  . LYS A 309 ? 0.19610 0.22640 0.23560 -0.03740 0.00940  0.02250  1768 LYS A CD  
4872 C  CE  . LYS A 309 ? 0.22880 0.23990 0.24320 -0.03500 0.01490  0.03760  1768 LYS A CE  
4873 N  NZ  . LYS A 309 ? 0.25350 0.24540 0.24950 -0.02810 0.01900  0.04330  1768 LYS A NZ  
4887 N  N   . ALA A 310 ? 0.11640 0.18620 0.20350 -0.01970 -0.00150 -0.01520 1769 ALA A N   
4888 C  CA  . ALA A 310 ? 0.13180 0.18170 0.18650 -0.01630 -0.01060 -0.02820 1769 ALA A CA  
4889 C  C   . ALA A 310 ? 0.13850 0.18940 0.18990 -0.01510 -0.00560 -0.02400 1769 ALA A C   
4890 O  O   . ALA A 310 ? 0.14090 0.19350 0.18430 -0.00660 -0.01000 -0.03160 1769 ALA A O   
4891 C  CB  . ALA A 310 ? 0.13970 0.18060 0.19150 -0.01720 -0.01870 -0.02970 1769 ALA A CB  
4897 N  N   . HIS A 311 ? 0.12660 0.19390 0.18870 -0.02930 -0.01440 -0.02060 1770 HIS A N   
4898 C  CA  . HIS A 311 ? 0.13170 0.20070 0.19810 -0.02860 -0.02260 -0.02270 1770 HIS A CA  
4899 C  C   . HIS A 311 ? 0.11770 0.19810 0.18630 -0.02410 -0.02490 -0.02200 1770 HIS A C   
4900 O  O   . HIS A 311 ? 0.12730 0.20380 0.20570 -0.01990 -0.02930 -0.01200 1770 HIS A O   
4901 C  CB  . HIS A 311 ? 0.15730 0.21320 0.22820 -0.03530 -0.03550 -0.02250 1770 HIS A CB  
4902 C  CG  . HIS A 311 ? 0.18920 0.22780 0.26580 -0.04860 -0.03860 -0.01900 1770 HIS A CG  
4903 N  ND1 . HIS A 311 ? 0.23220 0.23830 0.28800 -0.05100 -0.03400 -0.02250 1770 HIS A ND1 
4904 C  CD2 . HIS A 311 ? 0.20670 0.23450 0.28450 -0.05590 -0.04990 -0.01730 1770 HIS A CD2 
4905 C  CE1 . HIS A 311 ? 0.24880 0.23830 0.29680 -0.06260 -0.04060 -0.02560 1770 HIS A CE1 
4906 N  NE2 . HIS A 311 ? 0.24290 0.23790 0.30300 -0.06240 -0.03940 -0.01650 1770 HIS A NE2 
4914 N  N   . TRP A 312 ? 0.11070 0.18940 0.16680 -0.03300 -0.02020 -0.01900 1771 TRP A N   
4915 C  CA  . TRP A 312 ? 0.11330 0.18770 0.16030 -0.01810 -0.01210 -0.01330 1771 TRP A CA  
4916 C  C   . TRP A 312 ? 0.11050 0.18510 0.16680 -0.01440 -0.00390 -0.01100 1771 TRP A C   
4917 O  O   . TRP A 312 ? 0.11830 0.17920 0.18130 -0.01500 -0.00560 -0.01050 1771 TRP A O   
4918 C  CB  . TRP A 312 ? 0.11320 0.18730 0.15680 -0.00680 -0.01100 -0.01080 1771 TRP A CB  
4919 C  CG  . TRP A 312 ? 0.11470 0.17900 0.14570 0.01080  -0.00250 -0.02100 1771 TRP A CG  
4920 C  CD1 . TRP A 312 ? 0.12570 0.17750 0.13960 0.01120  -0.00710 -0.02800 1771 TRP A CD1 
4921 C  CD2 . TRP A 312 ? 0.11240 0.17950 0.15680 0.01300  0.00300  -0.01860 1771 TRP A CD2 
4922 N  NE1 . TRP A 312 ? 0.12610 0.17290 0.14510 0.01560  -0.00360 -0.01960 1771 TRP A NE1 
4923 C  CE2 . TRP A 312 ? 0.11110 0.17560 0.15210 0.01630  0.00750  -0.01240 1771 TRP A CE2 
4924 C  CE3 . TRP A 312 ? 0.12160 0.18440 0.15530 0.01430  -0.00870 -0.02330 1771 TRP A CE3 
4925 C  CZ2 . TRP A 312 ? 0.11220 0.18000 0.15030 0.01510  -0.00750 -0.02320 1771 TRP A CZ2 
4926 C  CZ3 . TRP A 312 ? 0.12720 0.18420 0.13520 0.01460  -0.01010 -0.02580 1771 TRP A CZ3 
4927 C  CH2 . TRP A 312 ? 0.11840 0.18460 0.13430 0.01550  -0.01710 -0.02020 1771 TRP A CH2 
4938 N  N   . THR A 313 ? 0.10300 0.18780 0.16730 -0.00830 0.00200  -0.00230 1772 THR A N   
4939 C  CA  . THR A 313 ? 0.10740 0.18940 0.15890 -0.00610 -0.00830 -0.00760 1772 THR A CA  
4940 C  C   . THR A 313 ? 0.10690 0.18770 0.16620 -0.00450 -0.01390 -0.00920 1772 THR A C   
4941 O  O   . THR A 313 ? 0.11860 0.19380 0.18250 -0.00840 -0.01720 -0.01850 1772 THR A O   
4942 C  CB  . THR A 313 ? 0.12350 0.19280 0.14490 -0.01020 -0.00590 -0.01600 1772 THR A CB  
4943 O  OG1 . THR A 313 ? 0.12170 0.19840 0.15510 -0.00940 0.00490  -0.01130 1772 THR A OG1 
4944 C  CG2 . THR A 313 ? 0.13190 0.19530 0.14540 -0.00910 -0.00700 -0.02420 1772 THR A CG2 
4952 N  N   . PRO A 314 ? 0.11270 0.18050 0.15850 -0.00170 -0.02450 -0.01260 1773 PRO A N   
4953 C  CA  . PRO A 314 ? 0.12850 0.18280 0.15000 -0.00510 -0.01700 -0.01260 1773 PRO A CA  
4954 C  C   . PRO A 314 ? 0.13220 0.18740 0.15360 0.00350  -0.01120 -0.01640 1773 PRO A C   
4955 O  O   . PRO A 314 ? 0.14520 0.18940 0.16110 0.01880  -0.01550 -0.00850 1773 PRO A O   
4956 C  CB  . PRO A 314 ? 0.13600 0.18340 0.14400 -0.00950 -0.00920 -0.00950 1773 PRO A CB  
4957 C  CG  . PRO A 314 ? 0.12860 0.17960 0.15180 -0.00570 -0.01120 -0.00640 1773 PRO A CG  
4958 C  CD  . PRO A 314 ? 0.13310 0.18050 0.15860 -0.00410 -0.02910 -0.00580 1773 PRO A CD  
4966 N  N   . PHE A 315 ? 0.12630 0.18990 0.15320 -0.00080 -0.00350 -0.02460 1774 PHE A N   
4967 C  CA  . PHE A 315 ? 0.12580 0.20000 0.14020 0.00440  0.00040  -0.02850 1774 PHE A CA  
4968 C  C   . PHE A 315 ? 0.13660 0.22390 0.14050 0.00620  -0.00520 -0.03620 1774 PHE A C   
4969 O  O   . PHE A 315 ? 0.13910 0.22610 0.15220 0.01850  -0.00160 -0.04290 1774 PHE A O   
4970 C  CB  . PHE A 315 ? 0.13110 0.19010 0.14360 0.01150  0.00320  -0.02690 1774 PHE A CB  
4971 C  CG  . PHE A 315 ? 0.11590 0.17650 0.13470 0.00320  -0.00530 -0.02080 1774 PHE A CG  
4972 C  CD1 . PHE A 315 ? 0.13040 0.16760 0.12640 0.01420  -0.01090 -0.01550 1774 PHE A CD1 
4973 C  CD2 . PHE A 315 ? 0.11320 0.17050 0.15400 0.00190  -0.01240 -0.02190 1774 PHE A CD2 
4974 C  CE1 . PHE A 315 ? 0.11940 0.16220 0.14100 0.00710  -0.00780 -0.02100 1774 PHE A CE1 
4975 C  CE2 . PHE A 315 ? 0.10600 0.16790 0.16140 0.00570  -0.01510 -0.01830 1774 PHE A CE2 
4976 C  CZ  . PHE A 315 ? 0.11190 0.16320 0.16020 0.00580  -0.01600 -0.02500 1774 PHE A CZ  
4986 N  N   . GLU A 316 ? 0.13340 0.24320 0.13290 -0.00630 -0.02330 -0.03830 1775 GLU A N   
4987 C  CA  . GLU A 316 ? 0.12950 0.26570 0.15010 -0.00250 -0.03580 -0.02670 1775 GLU A CA  
4988 C  C   . GLU A 316 ? 0.13830 0.27280 0.16270 0.00120  -0.03310 -0.02940 1775 GLU A C   
4989 O  O   . GLU A 316 ? 0.14450 0.27300 0.17600 0.00650  -0.03050 -0.02760 1775 GLU A O   
4990 C  CB  . GLU A 316 ? 0.14590 0.28550 0.17930 -0.00670 -0.02070 -0.02490 1775 GLU A CB  
4991 C  CG  . GLU A 316 ? 0.15450 0.30740 0.20670 -0.01080 -0.01470 -0.02400 1775 GLU A CG  
4992 C  CD  . GLU A 316 ? 0.16770 0.33010 0.23470 -0.02250 -0.02380 -0.02640 1775 GLU A CD  
4993 O  OE1 . GLU A 316 ? 0.16600 0.33840 0.26430 -0.03020 -0.03890 -0.02270 1775 GLU A OE1 
4994 O  OE2 . GLU A 316 ? 0.17620 0.34060 0.25810 -0.02490 -0.00640 -0.02570 1775 GLU A OE2 
5001 N  N   . GLY A 317 ? 0.14710 0.27550 0.16000 0.00480  -0.02320 -0.02990 1776 GLY A N   
5002 C  CA  . GLY A 317 ? 0.17010 0.27510 0.15490 0.01110  -0.02200 -0.01660 1776 GLY A CA  
5003 C  C   . GLY A 317 ? 0.19100 0.27460 0.15150 0.01020  -0.01690 -0.00830 1776 GLY A C   
5004 O  O   . GLY A 317 ? 0.21070 0.28190 0.15310 0.01260  -0.01670 0.00570  1776 GLY A O   
5008 N  N   . GLN A 318 ? 0.17570 0.26490 0.14940 0.00890  -0.01710 -0.01360 1777 GLN A N   
5009 C  CA  . GLN A 318 ? 0.18070 0.26040 0.16300 0.00590  -0.01390 -0.01460 1777 GLN A CA  
5010 C  C   . GLN A 318 ? 0.17790 0.26310 0.17060 0.00110  -0.01910 -0.01970 1777 GLN A C   
5011 O  O   . GLN A 318 ? 0.18620 0.26090 0.17360 -0.00790 -0.00900 -0.01970 1777 GLN A O   
5012 C  CB  . GLN A 318 ? 0.20140 0.25620 0.17200 0.01280  -0.00220 -0.01920 1777 GLN A CB  
5013 C  CG  . GLN A 318 ? 0.20860 0.25450 0.18990 0.02730  -0.00960 -0.03180 1777 GLN A CG  
5014 C  CD  . GLN A 318 ? 0.21200 0.25390 0.23350 0.03580  -0.02080 -0.04080 1777 GLN A CD  
5015 O  OE1 . GLN A 318 ? 0.24630 0.25890 0.28260 0.03710  -0.04400 -0.04760 1777 GLN A OE1 
5016 N  NE2 . GLN A 318 ? 0.20850 0.25200 0.23360 0.03140  -0.02420 -0.04080 1777 GLN A NE2 
5025 N  N   . LYS A 319 ? 0.19030 0.27330 0.19030 0.00930  -0.01790 -0.02790 1778 LYS A N   
5026 C  CA  A LYS A 319 ? 0.19740 0.27850 0.21240 0.00310  -0.00970 -0.02890 1778 LYS A CA  
5027 C  CA  B LYS A 319 ? 0.20200 0.28040 0.21680 0.00260  -0.01100 -0.02810 1778 LYS A CA  
5028 C  C   . LYS A 319 ? 0.18320 0.27620 0.21540 -0.00260 -0.00720 -0.03490 1778 LYS A C   
5029 O  O   . LYS A 319 ? 0.17950 0.28000 0.23620 0.00110  -0.01210 -0.04010 1778 LYS A O   
5030 C  CB  A LYS A 319 ? 0.22810 0.28840 0.23800 0.00420  -0.00370 -0.02610 1778 LYS A CB  
5031 C  CB  B LYS A 319 ? 0.23970 0.29330 0.25120 0.00320  -0.00770 -0.02360 1778 LYS A CB  
5032 C  CG  A LYS A 319 ? 0.26350 0.29780 0.27350 0.00660  -0.00940 -0.02160 1778 LYS A CG  
5033 C  CG  B LYS A 319 ? 0.28000 0.30490 0.29240 0.00650  -0.01510 -0.01920 1778 LYS A CG  
5034 C  CD  A LYS A 319 ? 0.29090 0.30520 0.30870 0.00690  -0.01010 -0.01880 1778 LYS A CD  
5035 C  CD  B LYS A 319 ? 0.31620 0.31610 0.33230 0.00780  -0.01870 -0.01620 1778 LYS A CD  
5036 C  CE  A LYS A 319 ? 0.31510 0.31100 0.33080 0.00670  -0.01030 -0.01610 1778 LYS A CE  
5037 C  CE  B LYS A 319 ? 0.34250 0.32370 0.35660 0.01220  -0.02290 -0.01180 1778 LYS A CE  
5038 N  NZ  A LYS A 319 ? 0.33300 0.31470 0.34810 0.00520  -0.01340 -0.01220 1778 LYS A NZ  
5039 N  NZ  B LYS A 319 ? 0.35720 0.32790 0.36650 0.01510  -0.02960 -0.00660 1778 LYS A NZ  
5066 N  N   . VAL A 320 ? 0.16210 0.26890 0.18610 -0.01290 -0.01080 -0.03410 1779 VAL A N   
5067 C  CA  . VAL A 320 ? 0.16560 0.26290 0.17090 -0.02250 -0.00790 -0.04450 1779 VAL A CA  
5068 C  C   . VAL A 320 ? 0.17250 0.26500 0.18500 -0.03080 -0.00520 -0.05260 1779 VAL A C   
5069 O  O   . VAL A 320 ? 0.17030 0.27080 0.20800 -0.03800 -0.00140 -0.05910 1779 VAL A O   
5070 C  CB  . VAL A 320 ? 0.16890 0.25630 0.16390 -0.03090 0.00660  -0.03830 1779 VAL A CB  
5071 C  CG1 . VAL A 320 ? 0.16640 0.25480 0.19110 -0.03040 0.01610  -0.03590 1779 VAL A CG1 
5072 C  CG2 . VAL A 320 ? 0.17550 0.25690 0.16510 -0.03200 -0.00930 -0.02850 1779 VAL A CG2 
5082 N  N   . LYS A 321 ? 0.17870 0.26140 0.17700 -0.02940 -0.00200 -0.05080 1780 LYS A N   
5083 C  CA  . LYS A 321 ? 0.19860 0.26060 0.21150 -0.02520 0.01330  -0.04720 1780 LYS A CA  
5084 C  C   . LYS A 321 ? 0.18800 0.24510 0.23930 -0.02600 -0.00030 -0.05110 1780 LYS A C   
5085 O  O   . LYS A 321 ? 0.19430 0.24040 0.24420 -0.03070 0.00040  -0.05970 1780 LYS A O   
5086 C  CB  . LYS A 321 ? 0.24420 0.27720 0.25630 -0.02000 0.02510  -0.03780 1780 LYS A CB  
5087 C  CG  . LYS A 321 ? 0.29530 0.29770 0.30260 -0.01450 0.03200  -0.02560 1780 LYS A CG  
5088 C  CD  . LYS A 321 ? 0.35010 0.31910 0.35670 -0.01340 0.04380  -0.01690 1780 LYS A CD  
5089 C  CE  . LYS A 321 ? 0.39460 0.33660 0.40030 -0.01650 0.04670  -0.00760 1780 LYS A CE  
5090 N  NZ  . LYS A 321 ? 0.41850 0.34960 0.42190 -0.01660 0.05140  -0.00280 1780 LYS A NZ  
5104 N  N   . GLY A 322 ? 0.19300 0.23300 0.25080 -0.02200 -0.02050 -0.04200 1781 GLY A N   
5105 C  CA  . GLY A 322 ? 0.20040 0.21990 0.25390 -0.01590 -0.02050 -0.04070 1781 GLY A CA  
5106 C  C   . GLY A 322 ? 0.19300 0.20590 0.22680 -0.01680 -0.02030 -0.04350 1781 GLY A C   
5107 O  O   . GLY A 322 ? 0.20320 0.20390 0.23740 -0.01490 -0.03310 -0.05000 1781 GLY A O   
5111 N  N   . THR A 323 ? 0.17830 0.19910 0.19960 -0.01160 -0.00670 -0.04290 1782 THR A N   
5112 C  CA  A THR A 323 ? 0.19030 0.20140 0.20920 -0.01620 -0.00160 -0.04040 1782 THR A CA  
5113 C  CA  B THR A 323 ? 0.18080 0.19940 0.18540 -0.01280 -0.00570 -0.04490 1782 THR A CA  
5114 C  C   . THR A 323 ? 0.17640 0.19660 0.19190 -0.02110 0.00040  -0.05070 1782 THR A C   
5115 O  O   . THR A 323 ? 0.17560 0.20080 0.19450 -0.01440 0.01450  -0.05000 1782 THR A O   
5116 C  CB  A THR A 323 ? 0.21720 0.20770 0.23770 -0.02320 -0.00190 -0.03440 1782 THR A CB  
5117 C  CB  B THR A 323 ? 0.19050 0.20190 0.17480 -0.00970 -0.01240 -0.04360 1782 THR A CB  
5118 O  OG1 A THR A 323 ? 0.24010 0.21450 0.27850 -0.02720 0.02130  -0.03220 1782 THR A OG1 
5119 O  OG1 B THR A 323 ? 0.20370 0.20420 0.17580 -0.00560 -0.02020 -0.04370 1782 THR A OG1 
5120 C  CG2 A THR A 323 ? 0.21490 0.20640 0.22200 -0.02540 -0.03800 -0.04050 1782 THR A CG2 
5121 C  CG2 B THR A 323 ? 0.18900 0.20180 0.16660 -0.01320 -0.01280 -0.04450 1782 THR A CG2 
5136 N  N   . VAL A 324 ? 0.17550 0.19260 0.19350 -0.03550 -0.00690 -0.04860 1783 VAL A N   
5137 C  CA  . VAL A 324 ? 0.19990 0.19190 0.18820 -0.04050 -0.00230 -0.05140 1783 VAL A CA  
5138 C  C   . VAL A 324 ? 0.18620 0.18910 0.20720 -0.04530 0.00510  -0.06210 1783 VAL A C   
5139 O  O   . VAL A 324 ? 0.16940 0.19560 0.22600 -0.04230 -0.00270 -0.07110 1783 VAL A O   
5140 C  CB  . VAL A 324 ? 0.23750 0.19500 0.18140 -0.04960 -0.01150 -0.03950 1783 VAL A CB  
5141 C  CG1 . VAL A 324 ? 0.22700 0.19780 0.19260 -0.04720 -0.02310 -0.03210 1783 VAL A CG1 
5142 C  CG2 . VAL A 324 ? 0.26270 0.19490 0.16800 -0.06030 -0.01220 -0.03630 1783 VAL A CG2 
5152 N  N   . ARG A 325 ? 0.19240 0.17950 0.20170 -0.04840 0.00970  -0.06290 1784 ARG A N   
5153 C  CA  . ARG A 325 ? 0.20700 0.18310 0.19810 -0.04710 0.00160  -0.04750 1784 ARG A CA  
5154 C  C   . ARG A 325 ? 0.20700 0.18050 0.19220 -0.04790 0.00920  -0.03880 1784 ARG A C   
5155 O  O   . ARG A 325 ? 0.21750 0.18610 0.21390 -0.05930 -0.00140 -0.02980 1784 ARG A O   
5156 C  CB  . ARG A 325 ? 0.24010 0.19120 0.20870 -0.03850 -0.01230 -0.04070 1784 ARG A CB  
5157 C  CG  . ARG A 325 ? 0.26630 0.20330 0.21620 -0.04130 -0.00720 -0.03000 1784 ARG A CG  
5158 C  CD  . ARG A 325 ? 0.28570 0.21400 0.23330 -0.04820 0.00430  -0.01900 1784 ARG A CD  
5159 N  NE  . ARG A 325 ? 0.31690 0.22880 0.23960 -0.05410 0.01460  -0.00860 1784 ARG A NE  
5160 C  CZ  . ARG A 325 ? 0.34820 0.24150 0.25590 -0.05490 0.02270  -0.00670 1784 ARG A CZ  
5161 N  NH1 . ARG A 325 ? 0.34540 0.25020 0.26520 -0.04980 0.03370  -0.00780 1784 ARG A NH1 
5162 N  NH2 . ARG A 325 ? 0.37980 0.24530 0.26930 -0.05100 0.01480  -0.01000 1784 ARG A NH2 
5176 N  N   . ARG A 326 ? 0.19020 0.17750 0.18930 -0.03950 0.02230  -0.03190 1785 ARG A N   
5177 C  CA  . ARG A 326 ? 0.19170 0.17870 0.19070 -0.03620 0.01800  -0.03540 1785 ARG A CA  
5178 C  C   . ARG A 326 ? 0.18480 0.16710 0.19360 -0.03750 0.02380  -0.03580 1785 ARG A C   
5179 O  O   . ARG A 326 ? 0.19130 0.16960 0.20200 -0.04370 0.02030  -0.03140 1785 ARG A O   
5180 C  CB  . ARG A 326 ? 0.38050 0.37990 0.38060 -0.00010 0.00000  -0.00010 1785 ARG A CB  
5183 N  N   . VAL A 327 ? 0.17060 0.15230 0.19350 -0.03760 0.02490  -0.03650 1786 VAL A N   
5184 C  CA  . VAL A 327 ? 0.16320 0.14500 0.17950 -0.03260 0.02180  -0.01920 1786 VAL A CA  
5185 C  C   . VAL A 327 ? 0.15930 0.13490 0.19450 -0.03470 0.01940  -0.02260 1786 VAL A C   
5186 O  O   . VAL A 327 ? 0.16410 0.13820 0.24280 -0.04330 0.01930  -0.01820 1786 VAL A O   
5187 C  CB  . VAL A 327 ? 0.16070 0.15080 0.19440 -0.03460 0.02010  -0.01020 1786 VAL A CB  
5188 C  CG1 . VAL A 327 ? 0.14800 0.15070 0.20240 -0.03610 0.01020  -0.00790 1786 VAL A CG1 
5189 C  CG2 . VAL A 327 ? 0.16450 0.15360 0.20020 -0.02950 0.00530  -0.01230 1786 VAL A CG2 
5199 N  N   . VAL A 328 ? 0.15780 0.13190 0.19980 -0.01980 0.02700  -0.01640 1787 VAL A N   
5200 C  CA  . VAL A 328 ? 0.16560 0.13910 0.22180 -0.01190 0.02860  -0.01520 1787 VAL A CA  
5201 C  C   . VAL A 328 ? 0.15200 0.13500 0.21140 -0.00730 0.03310  -0.01770 1787 VAL A C   
5202 O  O   . VAL A 328 ? 0.16170 0.12570 0.20960 -0.00800 0.03130  -0.01520 1787 VAL A O   
5203 C  CB  . VAL A 328 ? 0.17840 0.14720 0.22950 -0.01160 0.03250  -0.02380 1787 VAL A CB  
5204 C  CG1 . VAL A 328 ? 0.19040 0.15260 0.23900 -0.00890 0.04480  -0.02670 1787 VAL A CG1 
5205 C  CG2 . VAL A 328 ? 0.18040 0.15120 0.23540 -0.00790 0.03010  -0.02600 1787 VAL A CG2 
5215 N  N   . LEU A 329 ? 0.16220 0.13600 0.19790 -0.00460 0.02870  -0.01820 1788 LEU A N   
5216 C  CA  . LEU A 329 ? 0.15820 0.13140 0.18910 -0.00120 0.02610  -0.02650 1788 LEU A CA  
5217 C  C   . LEU A 329 ? 0.15680 0.12390 0.20320 -0.00330 0.01770  -0.02720 1788 LEU A C   
5218 O  O   . LEU A 329 ? 0.16680 0.11540 0.21570 -0.01090 0.03060  -0.02590 1788 LEU A O   
5219 C  CB  . LEU A 329 ? 0.16210 0.13280 0.19040 -0.00720 0.03070  -0.01620 1788 LEU A CB  
5220 C  CG  . LEU A 329 ? 0.16670 0.12690 0.19660 -0.00610 0.01730  -0.02160 1788 LEU A CG  
5221 C  CD1 . LEU A 329 ? 0.16590 0.12330 0.21100 -0.01170 0.01970  -0.02990 1788 LEU A CD1 
5222 C  CD2 . LEU A 329 ? 0.18110 0.12810 0.20330 0.00400  0.01770  -0.01400 1788 LEU A CD2 
5234 N  N   . ARG A 330 ? 0.15720 0.13200 0.20570 -0.00240 0.03190  -0.01530 1789 ARG A N   
5235 C  CA  . ARG A 330 ? 0.16660 0.13230 0.21420 -0.00100 0.01660  -0.01260 1789 ARG A CA  
5236 C  C   . ARG A 330 ? 0.17570 0.13080 0.21700 0.00230  0.02340  -0.01460 1789 ARG A C   
5237 O  O   . ARG A 330 ? 0.18480 0.12210 0.25840 -0.00370 0.02740  -0.00700 1789 ARG A O   
5238 C  CB  . ARG A 330 ? 0.15850 0.13050 0.20880 0.00200  0.00100  -0.00600 1789 ARG A CB  
5239 C  CG  . ARG A 330 ? 0.17020 0.12710 0.21200 -0.00390 0.00600  -0.00230 1789 ARG A CG  
5240 C  CD  . ARG A 330 ? 0.16280 0.12320 0.22570 -0.00230 0.02100  -0.00590 1789 ARG A CD  
5241 N  NE  . ARG A 330 ? 0.16980 0.11550 0.23780 -0.00440 0.03410  -0.00710 1789 ARG A NE  
5242 C  CZ  . ARG A 330 ? 0.18010 0.11040 0.23440 -0.00560 0.03600  -0.00550 1789 ARG A CZ  
5243 N  NH1 . ARG A 330 ? 0.18300 0.11080 0.22490 -0.00430 0.02770  0.00450  1789 ARG A NH1 
5244 N  NH2 . ARG A 330 ? 0.18410 0.10630 0.25240 -0.01710 0.03530  -0.00770 1789 ARG A NH2 
5258 N  N   . GLY A 331 ? 0.18310 0.13780 0.20770 0.00040  0.03100  -0.03620 1790 GLY A N   
5259 C  CA  . GLY A 331 ? 0.19710 0.14760 0.23350 -0.00650 0.03730  -0.05070 1790 GLY A CA  
5260 C  C   . GLY A 331 ? 0.21100 0.15510 0.25380 -0.01380 0.03060  -0.06490 1790 GLY A C   
5261 O  O   . GLY A 331 ? 0.23620 0.16850 0.29800 -0.01140 0.01020  -0.08490 1790 GLY A O   
5265 N  N   . GLU A 332 ? 0.19780 0.15450 0.23390 -0.02220 0.03760  -0.05090 1791 GLU A N   
5266 C  CA  . GLU A 332 ? 0.20240 0.16390 0.23690 -0.02390 0.02190  -0.04060 1791 GLU A CA  
5267 C  C   . GLU A 332 ? 0.19720 0.16110 0.23270 -0.02450 0.02240  -0.04180 1791 GLU A C   
5268 O  O   . GLU A 332 ? 0.18120 0.15520 0.23180 -0.03650 0.01870  -0.03500 1791 GLU A O   
5269 C  CB  . GLU A 332 ? 0.22900 0.18050 0.25600 -0.02010 0.00470  -0.02090 1791 GLU A CB  
5270 C  CG  . GLU A 332 ? 0.26840 0.19210 0.28350 -0.01890 -0.01740 -0.00970 1791 GLU A CG  
5271 C  CD  . GLU A 332 ? 0.31980 0.20750 0.34820 -0.01000 -0.02840 -0.01360 1791 GLU A CD  
5272 O  OE1 . GLU A 332 ? 0.34380 0.21870 0.37960 0.01180  -0.02550 -0.02510 1791 GLU A OE1 
5273 O  OE2 . GLU A 332 ? 0.33340 0.20550 0.37780 -0.03390 -0.02110 -0.01370 1791 GLU A OE2 
5280 N  N   . VAL A 333 ? 0.20970 0.15810 0.23540 -0.01310 0.02050  -0.04840 1792 VAL A N   
5281 C  CA  . VAL A 333 ? 0.22180 0.16150 0.22230 -0.01040 0.02420  -0.04090 1792 VAL A CA  
5282 C  C   . VAL A 333 ? 0.19850 0.14770 0.21810 -0.02510 0.03310  -0.04010 1792 VAL A C   
5283 O  O   . VAL A 333 ? 0.21660 0.14730 0.23410 -0.04510 0.04110  -0.05430 1792 VAL A O   
5284 C  CB  . VAL A 333 ? 0.25940 0.17960 0.23330 0.01200  0.00770  -0.03270 1792 VAL A CB  
5285 C  CG1 . VAL A 333 ? 0.27360 0.18110 0.24390 0.00950  -0.01360 -0.02320 1792 VAL A CG1 
5286 C  CG2 . VAL A 333 ? 0.27200 0.18840 0.24680 0.01820  0.01010  -0.03290 1792 VAL A CG2 
5296 N  N   . ALA A 334 ? 0.17730 0.14410 0.21700 -0.02140 0.02650  -0.04380 1793 ALA A N   
5297 C  CA  . ALA A 334 ? 0.16440 0.14710 0.20710 -0.02710 0.00820  -0.04510 1793 ALA A CA  
5298 C  C   . ALA A 334 ? 0.16690 0.14580 0.20870 -0.02310 0.01240  -0.04350 1793 ALA A C   
5299 O  O   . ALA A 334 ? 0.17430 0.15240 0.21870 -0.01600 -0.00140 -0.04290 1793 ALA A O   
5300 C  CB  . ALA A 334 ? 0.16270 0.14990 0.21560 -0.02130 -0.01330 -0.05220 1793 ALA A CB  
5306 N  N   . TYR A 335 ? 0.17290 0.14670 0.22710 -0.03360 0.00370  -0.04190 1794 TYR A N   
5307 C  CA  . TYR A 335 ? 0.17940 0.15030 0.22010 -0.03890 0.00390  -0.03870 1794 TYR A CA  
5308 C  C   . TYR A 335 ? 0.20390 0.15700 0.22230 -0.04790 0.01730  -0.03850 1794 TYR A C   
5309 O  O   . TYR A 335 ? 0.19140 0.15150 0.21630 -0.04840 0.02710  -0.03240 1794 TYR A O   
5310 C  CB  . TYR A 335 ? 0.17580 0.15430 0.21620 -0.02810 -0.00470 -0.04460 1794 TYR A CB  
5311 C  CG  . TYR A 335 ? 0.17020 0.16090 0.20920 -0.01930 0.00100  -0.05480 1794 TYR A CG  
5312 C  CD1 . TYR A 335 ? 0.18330 0.16920 0.21370 -0.01380 -0.00150 -0.05520 1794 TYR A CD1 
5313 C  CD2 . TYR A 335 ? 0.16270 0.16200 0.22090 -0.02000 -0.00540 -0.05450 1794 TYR A CD2 
5314 C  CE1 . TYR A 335 ? 0.16550 0.16810 0.21250 -0.00560 -0.00670 -0.06060 1794 TYR A CE1 
5315 C  CE2 . TYR A 335 ? 0.16800 0.16970 0.23070 -0.01950 -0.01290 -0.04780 1794 TYR A CE2 
5316 C  CZ  . TYR A 335 ? 0.16750 0.17150 0.23440 -0.00920 -0.01420 -0.05060 1794 TYR A CZ  
5317 O  OH  . TYR A 335 ? 0.18920 0.17630 0.27730 0.00040  -0.01490 -0.04150 1794 TYR A OH  
5327 N  N   A ILE A 336 ? 0.21740 0.16750 0.22980 -0.05550 0.02440  -0.03800 1795 ILE A N   
5328 N  N   B ILE A 336 ? 0.22770 0.17050 0.22590 -0.05430 0.01820  -0.04470 1795 ILE A N   
5329 C  CA  A ILE A 336 ? 0.24790 0.18070 0.23790 -0.07340 0.01770  -0.04780 1795 ILE A CA  
5330 C  CA  B ILE A 336 ? 0.25340 0.18420 0.23770 -0.06670 0.01240  -0.05400 1795 ILE A CA  
5331 C  C   A ILE A 336 ? 0.24450 0.19280 0.21040 -0.07980 0.00810  -0.05180 1795 ILE A C   
5332 C  C   B ILE A 336 ? 0.24920 0.19450 0.21710 -0.07470 0.00530  -0.05750 1795 ILE A C   
5333 O  O   A ILE A 336 ? 0.23540 0.19600 0.20670 -0.08890 0.01300  -0.04560 1795 ILE A O   
5334 O  O   B ILE A 336 ? 0.24430 0.19550 0.21570 -0.07890 0.00570  -0.05660 1795 ILE A O   
5335 C  CB  A ILE A 336 ? 0.29420 0.18110 0.27710 -0.08420 0.02490  -0.05370 1795 ILE A CB  
5336 C  CB  B ILE A 336 ? 0.28530 0.18720 0.27470 -0.07270 0.01500  -0.05780 1795 ILE A CB  
5337 C  CG1 A ILE A 336 ? 0.30180 0.18110 0.31250 -0.09590 0.01950  -0.05970 1795 ILE A CG1 
5338 C  CG1 B ILE A 336 ? 0.29560 0.19000 0.29900 -0.07650 0.01230  -0.06120 1795 ILE A CG1 
5339 C  CG2 A ILE A 336 ? 0.30940 0.18040 0.27330 -0.08970 0.02530  -0.05950 1795 ILE A CG2 
5340 C  CG2 B ILE A 336 ? 0.30360 0.18850 0.28290 -0.07140 0.01570  -0.05780 1795 ILE A CG2 
5341 C  CD1 A ILE A 336 ? 0.30960 0.18160 0.33200 -0.09520 0.01640  -0.06910 1795 ILE A CD1 
5342 C  CD1 B ILE A 336 ? 0.31100 0.19410 0.32160 -0.07430 0.01260  -0.05810 1795 ILE A CD1 
5365 N  N   . ASP A 337 ? 0.25000 0.20410 0.20970 -0.07600 -0.00190 -0.06220 1796 ASP A N   
5366 C  CA  . ASP A 337 ? 0.25260 0.22520 0.20730 -0.07880 -0.01160 -0.06830 1796 ASP A CA  
5367 C  C   . ASP A 337 ? 0.26370 0.23030 0.20520 -0.07520 -0.00850 -0.08090 1796 ASP A C   
5368 O  O   . ASP A 337 ? 0.25840 0.22570 0.20840 -0.06450 -0.01550 -0.08110 1796 ASP A O   
5369 C  CB  . ASP A 337 ? 0.24770 0.23690 0.21200 -0.08860 -0.00020 -0.06150 1796 ASP A CB  
5370 C  CG  . ASP A 337 ? 0.25370 0.24470 0.21530 -0.10250 -0.00550 -0.05350 1796 ASP A CG  
5371 O  OD1 . ASP A 337 ? 0.29870 0.25630 0.22150 -0.10860 -0.00530 -0.05590 1796 ASP A OD1 
5372 O  OD2 . ASP A 337 ? 0.24600 0.23780 0.21190 -0.08670 0.00250  -0.04970 1796 ASP A OD2 
5377 N  N   . GLY A 338 ? 0.28340 0.23950 0.22700 -0.07500 0.00610  -0.08150 1797 GLY A N   
5378 C  CA  . GLY A 338 ? 0.28650 0.25130 0.23000 -0.07160 0.01050  -0.08340 1797 GLY A CA  
5379 C  C   . GLY A 338 ? 0.27380 0.25730 0.23630 -0.07870 0.01820  -0.08150 1797 GLY A C   
5380 O  O   . GLY A 338 ? 0.32150 0.26570 0.28640 -0.06290 0.04860  -0.07590 1797 GLY A O   
5384 N  N   . GLN A 339 ? 0.23620 0.26400 0.22100 -0.08830 0.00010  -0.07770 1798 GLN A N   
5385 C  CA  . GLN A 339 ? 0.23780 0.27100 0.22970 -0.07930 0.01550  -0.07010 1798 GLN A CA  
5386 C  C   . GLN A 339 ? 0.21370 0.26710 0.20700 -0.07030 0.02700  -0.08060 1798 GLN A C   
5387 O  O   . GLN A 339 ? 0.21680 0.26910 0.20860 -0.07300 0.02820  -0.08790 1798 GLN A O   
5388 C  CB  . GLN A 339 ? 0.26640 0.27940 0.26260 -0.07820 0.01430  -0.06110 1798 GLN A CB  
5389 C  CG  . GLN A 339 ? 0.29050 0.29040 0.31580 -0.07030 0.00120  -0.05610 1798 GLN A CG  
5390 C  CD  . GLN A 339 ? 0.30090 0.30160 0.36650 -0.05960 -0.02360 -0.05890 1798 GLN A CD  
5391 O  OE1 . GLN A 339 ? 0.28280 0.30720 0.40370 -0.05260 -0.04840 -0.05560 1798 GLN A OE1 
5392 N  NE2 . GLN A 339 ? 0.31410 0.30470 0.37900 -0.06280 -0.00910 -0.06400 1798 GLN A NE2 
5401 N  N   . VAL A 340 ? 0.20200 0.26170 0.21260 -0.05960 0.02850  -0.08540 1799 VAL A N   
5402 C  CA  . VAL A 340 ? 0.21080 0.25600 0.21550 -0.05000 0.02670  -0.08290 1799 VAL A CA  
5403 C  C   . VAL A 340 ? 0.21550 0.23360 0.24050 -0.06840 0.02510  -0.07900 1799 VAL A C   
5404 O  O   . VAL A 340 ? 0.22730 0.23380 0.27190 -0.08410 0.03850  -0.05680 1799 VAL A O   
5405 C  CB  . VAL A 340 ? 0.22730 0.27570 0.21080 -0.02790 0.01510  -0.08590 1799 VAL A CB  
5406 C  CG1 . VAL A 340 ? 0.24500 0.28230 0.23270 -0.01890 -0.00120 -0.08310 1799 VAL A CG1 
5407 C  CG2 . VAL A 340 ? 0.23730 0.28650 0.20970 -0.01760 0.02560  -0.09050 1799 VAL A CG2 
5417 N  N   . LEU A 341 ? 0.22450 0.21840 0.23980 -0.06520 0.03190  -0.09100 1800 LEU A N   
5418 C  CA  . LEU A 341 ? 0.23780 0.21140 0.26040 -0.05980 0.02800  -0.09130 1800 LEU A CA  
5419 C  C   . LEU A 341 ? 0.24950 0.18700 0.26950 -0.03860 0.01110  -0.07280 1800 LEU A C   
5420 O  O   . LEU A 341 ? 0.29190 0.18350 0.31910 -0.03580 -0.00410 -0.08150 1800 LEU A O   
5421 C  CB  . LEU A 341 ? 0.26530 0.23870 0.28360 -0.06550 0.02090  -0.09750 1800 LEU A CB  
5422 C  CG  . LEU A 341 ? 0.28930 0.26030 0.29480 -0.07550 0.02510  -0.09750 1800 LEU A CG  
5423 C  CD1 . LEU A 341 ? 0.31440 0.27180 0.30490 -0.07620 0.03000  -0.09390 1800 LEU A CD1 
5424 C  CD2 . LEU A 341 ? 0.29610 0.26470 0.31550 -0.07750 0.01220  -0.10100 1800 LEU A CD2 
5436 N  N   . VAL A 342 ? 0.20560 0.17210 0.23430 -0.04030 0.00470  -0.05580 1801 VAL A N   
5437 C  CA  . VAL A 342 ? 0.20370 0.16430 0.23400 -0.03170 0.01840  -0.03070 1801 VAL A CA  
5438 C  C   . VAL A 342 ? 0.21810 0.15560 0.22790 -0.02310 0.02860  -0.03470 1801 VAL A C   
5439 O  O   . VAL A 342 ? 0.21490 0.15940 0.22590 -0.01560 0.02770  -0.03710 1801 VAL A O   
5440 C  CB  . VAL A 342 ? 0.19580 0.16400 0.23580 -0.03170 0.01460  -0.02260 1801 VAL A CB  
5441 C  CG1 . VAL A 342 ? 0.19560 0.16650 0.24370 -0.02870 0.01270  -0.01160 1801 VAL A CG1 
5442 C  CG2 . VAL A 342 ? 0.20830 0.16610 0.23980 -0.03680 0.00880  -0.01770 1801 VAL A CG2 
5452 N  N   . PRO A 343 ? 0.22360 0.14320 0.24820 -0.02420 0.04570  -0.02350 1802 PRO A N   
5453 C  CA  . PRO A 343 ? 0.22790 0.13980 0.24950 -0.03520 0.04280  -0.01350 1802 PRO A CA  
5454 C  C   . PRO A 343 ? 0.20830 0.14320 0.24450 -0.02900 0.03230  -0.00410 1802 PRO A C   
5455 O  O   . PRO A 343 ? 0.19000 0.14860 0.26880 -0.03150 0.02160  -0.00280 1802 PRO A O   
5456 C  CB  . PRO A 343 ? 0.25340 0.13610 0.27360 -0.03360 0.05160  -0.01330 1802 PRO A CB  
5457 C  CG  . PRO A 343 ? 0.25450 0.13410 0.27730 -0.02810 0.05150  -0.01080 1802 PRO A CG  
5458 C  CD  . PRO A 343 ? 0.23600 0.13910 0.26650 -0.02020 0.05340  -0.02130 1802 PRO A CD  
5466 N  N   . PRO A 344 ? 0.19730 0.14520 0.24470 -0.03660 0.01700  -0.00380 1803 PRO A N   
5467 C  CA  . PRO A 344 ? 0.18910 0.14020 0.23970 -0.03890 0.01760  -0.00670 1803 PRO A CA  
5468 C  C   . PRO A 344 ? 0.18780 0.13710 0.23780 -0.03930 0.03240  0.00550  1803 PRO A C   
5469 O  O   . PRO A 344 ? 0.19970 0.13450 0.24450 -0.05250 0.02230  -0.00270 1803 PRO A O   
5470 C  CB  . PRO A 344 ? 0.19420 0.14460 0.25060 -0.04200 0.00990  -0.01900 1803 PRO A CB  
5471 C  CG  . PRO A 344 ? 0.18970 0.14820 0.25020 -0.04450 0.01040  -0.01350 1803 PRO A CG  
5472 C  CD  . PRO A 344 ? 0.19460 0.14770 0.24880 -0.05150 0.00770  -0.01700 1803 PRO A CD  
5480 N  N   . GLY A 345 ? 0.18480 0.13410 0.23050 -0.03420 0.03810  0.00920  1804 GLY A N   
5481 C  CA  . GLY A 345 ? 0.19530 0.13210 0.20410 -0.03830 0.03420  0.01650  1804 GLY A CA  
5482 C  C   . GLY A 345 ? 0.19350 0.12340 0.19060 -0.03750 0.03070  0.00800  1804 GLY A C   
5483 O  O   . GLY A 345 ? 0.20390 0.13130 0.22260 -0.03750 0.02150  -0.00970 1804 GLY A O   
5487 N  N   . TYR A 346 ? 0.18460 0.11700 0.19510 -0.03600 0.04160  -0.00450 1805 TYR A N   
5488 C  CA  . TYR A 346 ? 0.16940 0.11920 0.20520 -0.03460 0.03860  -0.00570 1805 TYR A CA  
5489 C  C   . TYR A 346 ? 0.15310 0.12110 0.22550 -0.02920 0.02060  -0.01110 1805 TYR A C   
5490 O  O   . TYR A 346 ? 0.15750 0.12630 0.25820 -0.02600 0.02290  -0.01380 1805 TYR A O   
5491 C  CB  . TYR A 346 ? 0.17740 0.12620 0.22080 -0.02740 0.03840  -0.01120 1805 TYR A CB  
5492 C  CG  . TYR A 346 ? 0.17400 0.12390 0.22670 -0.01600 0.03600  -0.00870 1805 TYR A CG  
5493 C  CD1 . TYR A 346 ? 0.18560 0.12520 0.23850 -0.01060 0.04150  -0.00720 1805 TYR A CD1 
5494 C  CD2 . TYR A 346 ? 0.18110 0.11820 0.22290 -0.00670 0.02680  0.00300  1805 TYR A CD2 
5495 C  CE1 . TYR A 346 ? 0.19580 0.12490 0.25330 -0.00850 0.03270  -0.00780 1805 TYR A CE1 
5496 C  CE2 . TYR A 346 ? 0.18750 0.11600 0.22730 -0.00580 0.03580  -0.00400 1805 TYR A CE2 
5497 C  CZ  . TYR A 346 ? 0.19090 0.11870 0.23410 -0.00380 0.04260  -0.01600 1805 TYR A CZ  
5498 O  OH  . TYR A 346 ? 0.20410 0.11990 0.23830 0.00210  0.05220  -0.01480 1805 TYR A OH  
5508 N  N   . GLY A 347 ? 0.15440 0.11860 0.21310 -0.01400 0.01810  -0.01330 1806 GLY A N   
5509 C  CA  . GLY A 347 ? 0.16030 0.11250 0.20440 -0.01270 0.02900  -0.00370 1806 GLY A CA  
5510 C  C   . GLY A 347 ? 0.16340 0.11360 0.21390 -0.01650 0.02010  0.00260  1806 GLY A C   
5511 O  O   . GLY A 347 ? 0.16580 0.11840 0.22140 -0.02150 0.01840  -0.00420 1806 GLY A O   
5515 N  N   . GLN A 348 ? 0.16350 0.11360 0.20420 -0.01280 0.02320  0.01040  1807 GLN A N   
5516 C  CA  . GLN A 348 ? 0.15700 0.11510 0.18670 -0.01250 0.01450  0.01090  1807 GLN A CA  
5517 C  C   . GLN A 348 ? 0.14410 0.11130 0.17430 -0.00730 0.01330  0.01490  1807 GLN A C   
5518 O  O   . GLN A 348 ? 0.14940 0.12060 0.18630 -0.00370 0.02390  0.02000  1807 GLN A O   
5519 C  CB  . GLN A 348 ? 0.15490 0.12410 0.20080 -0.01110 0.01530  0.00960  1807 GLN A CB  
5520 C  CG  . GLN A 348 ? 0.16200 0.12920 0.21950 -0.00120 0.01900  0.00360  1807 GLN A CG  
5521 C  CD  . GLN A 348 ? 0.18330 0.13110 0.27380 -0.00060 0.00670  -0.00750 1807 GLN A CD  
5522 O  OE1 . GLN A 348 ? 0.18860 0.13220 0.32160 0.00210  0.01620  -0.00590 1807 GLN A OE1 
5523 N  NE2 . GLN A 348 ? 0.21440 0.13760 0.28770 0.00690  0.00080  -0.01900 1807 GLN A NE2 
5532 N  N   . ASP A 349 ? 0.15240 0.10660 0.19010 -0.01140 0.01550  0.00770  1808 ASP A N   
5533 C  CA  . ASP A 349 ? 0.14530 0.10990 0.17680 -0.00590 0.00010  -0.00140 1808 ASP A CA  
5534 C  C   . ASP A 349 ? 0.13510 0.10910 0.18810 -0.00250 -0.00210 0.00390  1808 ASP A C   
5535 O  O   . ASP A 349 ? 0.12920 0.11650 0.21010 0.00380  -0.00720 0.01080  1808 ASP A O   
5536 C  CB  . ASP A 349 ? 0.16550 0.12190 0.16820 -0.01020 0.01400  0.00060  1808 ASP A CB  
5537 C  CG  . ASP A 349 ? 0.18010 0.13600 0.17950 -0.01330 0.02900  0.01130  1808 ASP A CG  
5538 O  OD1 . ASP A 349 ? 0.14090 0.13320 0.21140 -0.00410 0.02310  0.01510  1808 ASP A OD1 
5539 O  OD2 . ASP A 349 ? 0.22430 0.15010 0.20150 -0.02190 0.03390  0.00490  1808 ASP A OD2 
5544 N  N   . VAL A 350 ? 0.13640 0.10430 0.18890 -0.01530 0.01440  -0.00330 1809 VAL A N   
5545 C  CA  . VAL A 350 ? 0.14570 0.10980 0.17870 -0.01160 0.03300  0.00950  1809 VAL A CA  
5546 C  C   . VAL A 350 ? 0.14060 0.11150 0.18330 -0.00750 0.01890  0.01530  1809 VAL A C   
5547 O  O   . VAL A 350 ? 0.14590 0.11360 0.20380 -0.00400 0.01980  0.01290  1809 VAL A O   
5548 C  CB  . VAL A 350 ? 0.16640 0.11970 0.18010 -0.01450 0.03170  0.00320  1809 VAL A CB  
5549 C  CG1 . VAL A 350 ? 0.18000 0.13260 0.18610 -0.01020 0.02110  -0.00110 1809 VAL A CG1 
5550 C  CG2 . VAL A 350 ? 0.17390 0.12150 0.18920 0.00390  0.02940  -0.00130 1809 VAL A CG2 
5560 N  N   . ARG A 351 ? 0.13730 0.11980 0.17620 -0.00140 0.00270  0.01490  1810 ARG A N   
5561 C  CA  . ARG A 351 ? 0.14240 0.12880 0.17160 -0.00070 -0.00590 0.01260  1810 ARG A CA  
5562 C  C   . ARG A 351 ? 0.15860 0.14190 0.18820 -0.00380 -0.02410 0.01150  1810 ARG A C   
5563 O  O   . ARG A 351 ? 0.19950 0.15200 0.21160 0.00050  -0.03120 0.00580  1810 ARG A O   
5564 C  CB  . ARG A 351 ? 0.15370 0.13030 0.17000 -0.00210 0.00920  0.01140  1810 ARG A CB  
5565 C  CG  . ARG A 351 ? 0.15750 0.13430 0.17700 -0.00910 0.02320  0.01000  1810 ARG A CG  
5566 C  CD  . ARG A 351 ? 0.16710 0.13750 0.17860 -0.01480 0.03350  0.00540  1810 ARG A CD  
5567 N  NE  . ARG A 351 ? 0.15880 0.13740 0.17490 -0.00840 0.04140  -0.00010 1810 ARG A NE  
5568 C  CZ  . ARG A 351 ? 0.13550 0.13020 0.15240 -0.00860 0.02770  0.01010  1810 ARG A CZ  
5569 N  NH1 . ARG A 351 ? 0.13010 0.13190 0.15540 0.00550  0.01170  0.01360  1810 ARG A NH1 
5570 N  NH2 . ARG A 351 ? 0.13480 0.13020 0.16830 -0.00260 0.01650  0.01960  1810 ARG A NH2 
5584 N  N   . LYS A 352 ? 0.15870 0.14690 0.22360 -0.00160 -0.02770 0.01730  1811 LYS A N   
5585 C  CA  . LYS A 352 ? 0.18050 0.16330 0.23870 0.00490  -0.01060 0.02620  1811 LYS A CA  
5586 C  C   . LYS A 352 ? 0.18270 0.15950 0.24970 0.00830  -0.00350 0.03410  1811 LYS A C   
5587 O  O   . LYS A 352 ? 0.20940 0.16870 0.28050 0.02310  -0.00020 0.05140  1811 LYS A O   
5588 C  CB  . LYS A 352 ? 0.21490 0.18850 0.24940 0.01420  0.02470  0.02000  1811 LYS A CB  
5589 C  CG  . LYS A 352 ? 0.27740 0.22380 0.30160 0.01590  0.03940  0.00740  1811 LYS A CG  
5590 C  CD  . LYS A 352 ? 0.33900 0.25300 0.35710 0.01310  0.03760  0.00390  1811 LYS A CD  
5591 C  CE  . LYS A 352 ? 0.37840 0.26980 0.39430 0.00230  0.03930  0.00650  1811 LYS A CE  
5592 N  NZ  . LYS A 352 ? 0.38690 0.27150 0.39060 -0.00630 0.04480  0.02200  1811 LYS A NZ  
5606 N  N   . TRP A 353 ? 0.15760 0.15430 0.24730 0.00110  0.00430  0.02440  1812 TRP A N   
5607 C  CA  . TRP A 353 ? 0.16170 0.15320 0.25230 -0.00030 0.01830  0.01330  1812 TRP A CA  
5608 C  C   . TRP A 353 ? 0.17630 0.17340 0.29580 -0.00070 0.00270  0.02080  1812 TRP A C   
5609 O  O   . TRP A 353 ? 0.17990 0.17390 0.30170 -0.01400 0.00220  0.01720  1812 TRP A O   
5610 C  CB  . TRP A 353 ? 0.16580 0.14690 0.23000 -0.00220 0.02620  0.00030  1812 TRP A CB  
5611 C  CG  . TRP A 353 ? 0.16750 0.14310 0.20670 -0.00530 0.02650  0.00410  1812 TRP A CG  
5612 C  CD1 . TRP A 353 ? 0.17550 0.14750 0.21160 -0.00730 0.02810  0.00510  1812 TRP A CD1 
5613 C  CD2 . TRP A 353 ? 0.16870 0.14240 0.21080 -0.01040 0.02660  -0.00520 1812 TRP A CD2 
5614 N  NE1 . TRP A 353 ? 0.16920 0.14520 0.21770 -0.02180 0.03080  0.00250  1812 TRP A NE1 
5615 C  CE2 . TRP A 353 ? 0.17070 0.13840 0.20660 -0.01620 0.03790  -0.00370 1812 TRP A CE2 
5616 C  CE3 . TRP A 353 ? 0.17490 0.14260 0.21490 -0.01040 0.02770  -0.00320 1812 TRP A CE3 
5617 C  CZ2 . TRP A 353 ? 0.17420 0.13650 0.20510 -0.02000 0.04200  -0.01030 1812 TRP A CZ2 
5618 C  CZ3 . TRP A 353 ? 0.19410 0.14470 0.22040 -0.01770 0.04020  0.00640  1812 TRP A CZ3 
5619 C  CH2 . TRP A 353 ? 0.18800 0.14010 0.21550 -0.02010 0.04340  -0.00050 1812 TRP A CH2 
5630 N  N   . PRO A 354 ? 0.19930 0.19490 0.33960 0.00460  -0.00120 0.02080  1813 PRO A N   
5631 C  CA  . PRO A 354 ? 0.20250 0.21310 0.34670 0.00180  -0.00270 0.01660  1813 PRO A CA  
5632 C  C   . PRO A 354 ? 0.19450 0.22720 0.31820 -0.01080 0.00530  0.00230  1813 PRO A C   
5633 O  O   . PRO A 354 ? 0.20170 0.24230 0.32890 -0.02800 -0.00440 0.00130  1813 PRO A O   
5634 C  CB  . PRO A 354 ? 0.22110 0.21630 0.38030 0.01030  0.00800  0.01920  1813 PRO A CB  
5635 C  CG  . PRO A 354 ? 0.23010 0.21190 0.38110 0.01720  -0.00150 0.01890  1813 PRO A CG  
5636 C  CD  . PRO A 354 ? 0.22020 0.20380 0.36590 0.01600  -0.00360 0.02040  1813 PRO A CD  
5644 N  N   . GLN A 355 ? 0.18730 0.22830 0.28890 -0.01150 0.02330  -0.00440 1814 GLN A N   
5645 C  CA  . GLN A 355 ? 0.21160 0.23410 0.27170 -0.01480 0.01930  -0.00220 1814 GLN A CA  
5646 C  C   . GLN A 355 ? 0.17560 0.21870 0.25300 -0.02250 0.02290  0.00490  1814 GLN A C   
5647 O  O   . GLN A 355 ? 0.17060 0.22470 0.27670 -0.02140 0.01160  0.01950  1814 GLN A O   
5648 C  CB  . GLN A 355 ? 0.26310 0.24580 0.30040 -0.01260 0.00700  -0.00180 1814 GLN A CB  
5649 C  CG  . GLN A 355 ? 0.26900 0.24850 0.31520 0.00190  0.00260  0.00370  1814 GLN A CG  
5650 C  CD  . GLN A 355 ? 0.26380 0.24810 0.32700 0.01300  0.00200  0.00480  1814 GLN A CD  
5651 O  OE1 . GLN A 355 ? 0.25030 0.24970 0.34970 0.02170  -0.00820 -0.00280 1814 GLN A OE1 
5652 N  NE2 . GLN A 355 ? 0.27730 0.24740 0.34090 0.01750  0.00940  0.01210  1814 GLN A NE2 
5661 N  N   . GLY A 356 ? 0.16030 0.20240 0.23800 -0.02940 0.02910  0.00840  1815 GLY A N   
5662 C  CA  . GLY A 356 ? 0.15800 0.19000 0.22140 -0.01590 0.01430  0.01740  1815 GLY A CA  
5663 C  C   . GLY A 356 ? 0.15500 0.17810 0.22610 -0.00080 0.00570  0.02210  1815 GLY A C   
5664 O  O   . GLY A 356 ? 0.16540 0.16810 0.25180 0.02900  0.00080  0.02950  1815 GLY A O   
5668 N  N   . ALA A 357 ? 0.18160 0.18400 0.22840 -0.01370 0.00670  0.01860  1816 ALA A N   
5669 C  CA  . ALA A 357 ? 0.19040 0.19270 0.23220 -0.02630 0.01370  0.00850  1816 ALA A CA  
5670 C  C   . ALA A 357 ? 0.19350 0.19810 0.20120 -0.03580 0.03770  0.00050  1816 ALA A C   
5671 O  O   . ALA A 357 ? 0.20230 0.20210 0.20140 -0.03570 0.04560  -0.01440 1816 ALA A O   
5672 C  CB  . ALA A 357 ? 0.20340 0.19540 0.24970 -0.02690 0.00280  0.00770  1816 ALA A CB  
5678 N  N   . VAL A 358 ? 0.20170 0.19890 0.19400 -0.04590 0.03180  -0.00210 1817 VAL A N   
5679 C  CA  . VAL A 358 ? 0.19510 0.20630 0.18340 -0.04320 0.02970  0.00300  1817 VAL A CA  
5680 C  C   . VAL A 358 ? 0.19130 0.22080 0.18780 -0.05260 0.03850  -0.00110 1817 VAL A C   
5681 O  O   . VAL A 358 ? 0.17150 0.21480 0.18600 -0.03520 0.02530  0.00270  1817 VAL A O   
5682 C  CB  . VAL A 358 ? 0.19670 0.20110 0.16310 -0.03270 0.00700  0.00270  1817 VAL A CB  
5683 C  CG1 . VAL A 358 ? 0.21070 0.19680 0.16970 -0.02860 -0.01200 0.01070  1817 VAL A CG1 
5684 C  CG2 . VAL A 358 ? 0.19880 0.20380 0.16200 -0.01980 0.00810  -0.00400 1817 VAL A CG2 
5694 N  N   . PRO A 359 ? 0.20720 0.25000 0.20860 -0.06850 0.04050  -0.00320 1818 PRO A N   
5695 C  CA  . PRO A 359 ? 0.19700 0.26450 0.21170 -0.06380 0.04620  0.00240  1818 PRO A CA  
5696 C  C   . PRO A 359 ? 0.18430 0.27250 0.19750 -0.04650 0.02800  0.01470  1818 PRO A C   
5697 O  O   . PRO A 359 ? 0.19620 0.26810 0.18110 -0.04880 0.01350  0.01210  1818 PRO A O   
5698 C  CB  . PRO A 359 ? 0.21580 0.27220 0.22470 -0.07650 0.05090  -0.01160 1818 PRO A CB  
5699 C  CG  . PRO A 359 ? 0.23860 0.27110 0.24100 -0.08260 0.04480  -0.01890 1818 PRO A CG  
5700 C  CD  . PRO A 359 ? 0.23050 0.26290 0.22720 -0.08410 0.04810  -0.01480 1818 PRO A CD  
5708 N  N   . GLN A 360 ? 0.19230 0.29020 0.21970 -0.02480 0.03040  0.02990  1819 GLN A N   
5709 C  CA  . GLN A 360 ? 0.20290 0.31550 0.24910 -0.00140 0.01180  0.03510  1819 GLN A CA  
5710 C  C   . GLN A 360 ? 0.20740 0.33850 0.26670 0.01300  -0.00500 0.03470  1819 GLN A C   
5711 O  O   . GLN A 360 ? 0.18870 0.34100 0.28770 0.01530  0.00670  0.03040  1819 GLN A O   
5712 C  CB  . GLN A 360 ? 0.22180 0.32310 0.27960 0.00220  0.01460  0.04380  1819 GLN A CB  
5713 C  CG  . GLN A 360 ? 0.26060 0.33070 0.30590 0.00130  0.02930  0.04860  1819 GLN A CG  
5714 C  CD  . GLN A 360 ? 0.30780 0.34010 0.32800 0.00550  0.02190  0.04700  1819 GLN A CD  
5715 O  OE1 . GLN A 360 ? 0.33440 0.34640 0.35220 0.00160  0.03470  0.05120  1819 GLN A OE1 
5716 N  NE2 . GLN A 360 ? 0.31970 0.34440 0.31630 0.01070  0.00780  0.04180  1819 GLN A NE2 
5725 N  N   . LEU A 361 ? 0.24090 0.36440 0.27210 0.02140  -0.02130 0.03460  1820 LEU A N   
5726 C  CA  . LEU A 361 ? 0.28910 0.38930 0.29060 0.02530  -0.02240 0.03670  1820 LEU A CA  
5727 C  C   . LEU A 361 ? 0.34620 0.41500 0.32380 0.03280  -0.00470 0.03890  1820 LEU A C   
5728 O  O   . LEU A 361 ? 0.35370 0.41810 0.32650 0.03500  -0.00310 0.04390  1820 LEU A O   
5729 C  CB  . LEU A 361 ? 0.29240 0.38970 0.28940 0.02150  -0.02440 0.03820  1820 LEU A CB  
5730 C  CG  . LEU A 361 ? 0.29940 0.38810 0.29060 0.01790  -0.02690 0.03830  1820 LEU A CG  
5731 C  CD1 . LEU A 361 ? 0.31080 0.38980 0.31000 0.01800  -0.02100 0.02690  1820 LEU A CD1 
5732 C  CD2 . LEU A 361 ? 0.28570 0.38720 0.27850 0.01280  -0.03580 0.04650  1820 LEU A CD2 
5744 N  N   . PRO A 362 ? 0.40430 0.43590 0.36250 0.03350  -0.00120 0.03430  1821 PRO A N   
5745 C  CA  . PRO A 362 ? 0.44420 0.44820 0.40620 0.03130  0.00520  0.02380  1821 PRO A CA  
5746 C  C   . PRO A 362 ? 0.48020 0.45710 0.44810 0.02280  0.01250  0.01100  1821 PRO A C   
5747 O  O   . PRO A 362 ? 0.48440 0.45860 0.44640 0.02060  0.00740  0.00790  1821 PRO A O   
5748 C  CB  . PRO A 362 ? 0.44280 0.44880 0.39670 0.03560  0.00250  0.02570  1821 PRO A CB  
5749 C  CG  . PRO A 362 ? 0.43650 0.44670 0.38810 0.03810  0.00430  0.02780  1821 PRO A CG  
5750 C  CD  . PRO A 362 ? 0.42210 0.44180 0.37260 0.03830  0.00090  0.03180  1821 PRO A CD  
5751 O  OXT . PRO A 362 ? 0.50360 0.46260 0.48460 0.01880  0.01370  0.00360  1821 PRO A OXT 
5759 C  C   . FMT B .   ? 0.50140 0.41890 0.41090 0.00150  -0.06890 0.01430  1901 FMT A C   
5760 O  O1  . FMT B .   ? 0.49250 0.41850 0.40480 0.00000  -0.07340 0.01580  1901 FMT A O1  
5761 O  O2  . FMT B .   ? 0.50380 0.41770 0.41900 0.00520  -0.06920 0.01540  1901 FMT A O2  
5764 C  C   . FMT C .   ? 0.32240 0.38870 0.38550 0.06560  0.02980  0.07020  1902 FMT A C   
5765 O  O1  . FMT C .   ? 0.32430 0.38900 0.38800 0.06310  0.04150  0.06820  1902 FMT A O1  
5766 O  O2  . FMT C .   ? 0.31530 0.38810 0.38210 0.06590  0.02930  0.06230  1902 FMT A O2  
5769 C  C   . FMT D .   ? 0.45530 0.42570 0.42840 0.06600  -0.02980 0.01160  1903 FMT A C   
5770 O  O1  . FMT D .   ? 0.47540 0.42740 0.44700 0.05720  -0.02540 0.01500  1903 FMT A O1  
5771 O  O2  . FMT D .   ? 0.43320 0.42550 0.40670 0.07080  -0.03560 0.00990  1903 FMT A O2  
5774 C  C   . FMT E .   ? 0.18150 0.25890 0.23890 -0.05090 -0.01880 0.01940  1904 FMT A C   
5775 O  O1  . FMT E .   ? 0.16650 0.25900 0.22630 -0.05000 -0.01130 0.00740  1904 FMT A O1  
5776 O  O2  . FMT E .   ? 0.22100 0.26400 0.26950 -0.05020 -0.02960 0.02450  1904 FMT A O2  
5779 C  C   . FMT F .   ? 0.48230 0.51760 0.51880 -0.01120 -0.06820 -0.02510 1905 FMT A C   
5780 O  O1  . FMT F .   ? 0.48400 0.51680 0.52110 -0.01220 -0.07400 -0.02160 1905 FMT A O1  
5781 O  O2  . FMT F .   ? 0.48570 0.51820 0.52940 -0.01030 -0.05750 -0.02630 1905 FMT A O2  
5784 C  C   . FMT G .   ? 0.26880 0.23470 0.28580 -0.00460 -0.00310 -0.03390 1906 FMT A C   
5785 O  O1  . FMT G .   ? 0.21840 0.21750 0.25040 0.00680  0.02440  -0.04560 1906 FMT A O1  
5786 O  O2  . FMT G .   ? 0.29000 0.23850 0.29510 -0.00970 -0.03870 -0.01860 1906 FMT A O2  
5789 C  C   . FMT H .   ? 0.37080 0.33420 0.32890 0.01420  -0.01980 -0.00750 1907 FMT A C   
5790 O  O1  . FMT H .   ? 0.39160 0.33810 0.34480 0.01360  -0.01700 -0.01350 1907 FMT A O1  
5791 O  O2  . FMT H .   ? 0.36170 0.33480 0.33960 0.00780  -0.01510 0.00360  1907 FMT A O2  
5794 C  C   . FMT I .   ? 0.18500 0.18430 0.26350 -0.00760 0.03350  0.00440  1908 FMT A C   
5795 O  O1  . FMT I .   ? 0.16980 0.17840 0.24170 -0.00050 0.02910  0.01570  1908 FMT A O1  
5796 O  O2  . FMT I .   ? 0.16970 0.17750 0.24260 -0.01210 0.02640  -0.00610 1908 FMT A O2  
5799 C  C   . FMT J .   ? 0.36730 0.38190 0.34160 0.00240  0.01770  -0.01140 1909 FMT A C   
5800 O  O1  . FMT J .   ? 0.37390 0.38550 0.35350 0.00740  0.01200  -0.01560 1909 FMT A O1  
5801 O  O2  . FMT J .   ? 0.36130 0.38500 0.36430 -0.00530 0.00680  -0.00600 1909 FMT A O2  
5804 ZN ZN  . ZN  K .   ? 0.11820 0.12340 0.13510 -0.00730 -0.00580 -0.00460 1910 ZN  A ZN  
5805 ZN ZN  . ZN  L .   ? 0.10230 0.12740 0.13960 -0.00520 0.00360  -0.00160 1911 ZN  A ZN  
5806 ZN ZN  . ZN  M .   ? 0.14370 0.12590 0.18110 -0.00450 -0.00120 -0.00460 1912 ZN  A ZN  
5807 ZN ZN  . ZN  N .   ? 0.13190 0.15020 0.16720 -0.00120 0.00750  -0.02240 1913 ZN  A ZN  
5808 C  C1  . GOL O .   ? 0.27460 0.27850 0.26450 -0.01640 0.00480  0.00550  1914 GOL A C1  
5809 O  O1  . GOL O .   ? 0.32580 0.29760 0.29480 -0.02260 0.00320  -0.02180 1914 GOL A O1  
5810 C  C2  . GOL O .   ? 0.29300 0.27230 0.28080 0.00940  0.00200  0.01530  1914 GOL A C2  
5811 O  O2  . GOL O .   ? 0.29320 0.26380 0.28860 0.00640  -0.01300 -0.00360 1914 GOL A O2  
5812 C  C3  . GOL O .   ? 0.26950 0.28060 0.27480 0.00060  -0.00930 0.00770  1914 GOL A C3  
5813 O  O3  . GOL O .   ? 0.32380 0.28950 0.29860 0.00370  -0.02690 0.01030  1914 GOL A O3  
5821 NA NA  . NA  P .   ? 0.31580 0.31510 0.35070 -0.02560 0.03620  0.00120  1915 NA  A NA  
5822 O  O   . HOH Q .   ? 0.28980 0.29100 0.31220 0.16060  0.01160  0.06700  2001 HOH A O   
5823 O  O   . HOH Q .   ? 0.37040 0.41480 0.38670 -0.02840 0.06350  0.01090  2002 HOH A O   
5824 O  O   . HOH Q .   ? 0.38070 0.38070 0.38070 -0.00000 -0.00000 0.00000  2003 HOH A O   
5825 O  O   . HOH Q .   ? 0.44240 0.43530 0.42630 0.01030  -0.02750 0.02790  2004 HOH A O   
5826 O  O   . HOH Q .   ? 0.36370 0.36610 0.37120 0.00680  -0.00600 0.00150  2005 HOH A O   
5827 O  O   . HOH Q .   ? 0.30880 0.40790 0.29550 0.01170  0.05790  -0.08360 2006 HOH A O   
5828 O  O   . HOH Q .   ? 0.28180 0.21110 0.36910 0.00270  0.02320  0.08260  2007 HOH A O   
5829 O  O   . HOH Q .   ? 0.22890 0.34760 0.29740 0.07180  0.07890  0.02650  2008 HOH A O   
5830 O  O   . HOH Q .   ? 0.44700 0.43850 0.43650 -0.01060 0.01670  -0.00660 2009 HOH A O   
5831 O  O   . HOH Q .   ? 0.44910 0.44580 0.42460 -0.04890 -0.02990 0.00630  2010 HOH A O   
5832 O  O   . HOH Q .   ? 0.43560 0.35080 0.36830 -0.07700 0.06120  0.06190  2011 HOH A O   
5833 O  O   . HOH Q .   ? 0.41320 0.40200 0.54150 0.08120  0.00110  0.04360  2012 HOH A O   
5834 O  O   . HOH Q .   ? 0.47640 0.33350 0.29000 0.07420  -0.04060 0.04650  2013 HOH A O   
5835 O  O   . HOH Q .   ? 0.51030 0.47910 0.62320 0.08460  0.07370  -0.10200 2014 HOH A O   
5836 O  O   . HOH Q .   ? 0.51770 0.59440 0.55610 0.06530  0.02810  0.07500  2015 HOH A O   
5837 O  O   . HOH Q .   ? 0.31120 0.38230 0.37080 0.00990  0.00870  -0.11200 2016 HOH A O   
5838 O  O   . HOH Q .   ? 0.32240 0.44440 0.48870 -0.05160 -0.07870 0.08110  2017 HOH A O   
5839 O  O   . HOH Q .   ? 0.56090 0.43310 0.47550 -0.09360 -0.02440 0.05330  2018 HOH A O   
5840 O  O   . HOH Q .   ? 0.36160 0.43080 0.36230 -0.10260 0.03240  -0.07910 2019 HOH A O   
5841 O  O   . HOH Q .   ? 0.47820 0.55510 0.53620 -0.01670 -0.07540 0.00750  2020 HOH A O   
5842 O  O   . HOH Q .   ? 0.44190 0.51830 0.47880 -0.01930 0.05280  -0.09040 2021 HOH A O   
5843 O  O   . HOH Q .   ? 0.25770 0.35030 0.36030 0.02150  0.00230  -0.07390 2022 HOH A O   
5844 O  O   . HOH Q .   ? 0.14080 0.27790 0.24960 -0.02000 -0.00130 0.00290  2023 HOH A O   
5845 O  O   . HOH Q .   ? 0.45440 0.44150 0.53380 0.10730  0.06110  -0.07900 2024 HOH A O   
5846 O  O   . HOH Q .   ? 0.30590 0.43390 0.31170 0.00530  -0.01410 0.10440  2025 HOH A O   
5847 O  O   . HOH Q .   ? 0.41180 0.41150 0.41480 -0.03630 -0.03500 -0.01650 2026 HOH A O   
5848 O  O   . HOH Q .   ? 0.52620 0.38980 0.38280 -0.00400 0.01260  0.00580  2027 HOH A O   
5849 O  O   . HOH Q .   ? 0.41810 0.46800 0.35610 -0.10930 0.01260  -0.08820 2028 HOH A O   
5850 O  O   . HOH Q .   ? 0.30300 0.40130 0.30670 0.01490  -0.04440 0.03560  2029 HOH A O   
5851 O  O   . HOH Q .   ? 0.51300 0.48040 0.52510 0.06760  0.06720  0.00030  2030 HOH A O   
5852 O  O   . HOH Q .   ? 0.30140 0.21370 0.15010 0.12120  -0.04770 -0.03010 2031 HOH A O   
5853 O  O   . HOH Q .   ? 0.28900 0.37580 0.38850 0.15980  0.05900  0.13460  2032 HOH A O   
5854 O  O   . HOH Q .   ? 0.41230 0.45920 0.42690 0.03340  0.02790  0.00940  2033 HOH A O   
5855 O  O   . HOH Q .   ? 0.36810 0.53380 0.40780 0.08630  0.13650  0.13430  2034 HOH A O   
5856 O  O   . HOH Q .   ? 0.42080 0.34140 0.26970 -0.07220 0.05230  0.01110  2035 HOH A O   
5857 O  O   . HOH Q .   ? 0.15670 0.17460 0.17700 0.01700  -0.01550 -0.02320 2036 HOH A O   
5858 O  O   . HOH Q .   ? 0.28480 0.36660 0.44450 -0.12500 -0.04710 0.03060  2037 HOH A O   
5859 O  O   . HOH Q .   ? 0.40590 0.32640 0.37310 -0.10390 0.17730  0.01650  2038 HOH A O   
5860 O  O   . HOH Q .   ? 0.44860 0.29790 0.24210 -0.04440 -0.05530 -0.08340 2039 HOH A O   
5861 O  O   . HOH Q .   ? 0.32890 0.33400 0.35130 -0.00900 0.01200  0.00070  2040 HOH A O   
5862 O  O   . HOH Q .   ? 0.22350 0.31600 0.29910 0.00320  -0.01250 -0.00660 2041 HOH A O   
5863 O  O   . HOH Q .   ? 0.31110 0.38370 0.34450 -0.16260 -0.02670 -0.06900 2042 HOH A O   
5864 O  O   . HOH Q .   ? 0.20160 0.28700 0.27560 -0.01380 -0.04760 -0.00300 2043 HOH A O   
5865 O  O   . HOH Q .   ? 0.21550 0.25560 0.20040 -0.06600 -0.02490 0.00810  2044 HOH A O   
5866 O  O   . HOH Q .   ? 0.41990 0.29370 0.28000 -0.10030 -0.02590 -0.05010 2045 HOH A O   
5867 O  O   . HOH Q .   ? 0.23350 0.41450 0.44220 0.03030  0.06250  -0.03820 2046 HOH A O   
5868 O  O   . HOH Q .   ? 0.38660 0.28990 0.38970 -0.04610 0.01240  0.04370  2047 HOH A O   
5869 O  O   . HOH Q .   ? 0.32120 0.16250 0.34540 -0.05260 -0.03060 0.00080  2048 HOH A O   
5870 O  O   . HOH Q .   ? 0.43160 0.25310 0.27760 0.00450  -0.03610 -0.07390 2049 HOH A O   
5871 O  O   . HOH Q .   ? 0.47760 0.32740 0.49210 -0.00320 -0.08500 0.03830  2050 HOH A O   
5872 O  O   . HOH Q .   ? 0.37190 0.49150 0.36270 0.02380  -0.02580 -0.03180 2051 HOH A O   
5873 O  O   . HOH Q .   ? 0.22980 0.28300 0.33860 0.05770  -0.00110 0.01710  2052 HOH A O   
5874 O  O   . HOH Q .   ? 0.35410 0.25370 0.26170 0.07730  -0.01000 -0.05450 2053 HOH A O   
5875 O  O   . HOH Q .   ? 0.30190 0.47140 0.24440 0.00320  -0.01850 0.08840  2054 HOH A O   
5876 O  O   . HOH Q .   ? 0.29750 0.16390 0.40300 0.00740  -0.08800 -0.03440 2055 HOH A O   
5877 O  O   . HOH Q .   ? 0.26440 0.36830 0.33230 -0.04720 0.05460  -0.07430 2056 HOH A O   
5878 O  O   . HOH Q .   ? 0.41100 0.44180 0.44940 0.05380  -0.00740 -0.00410 2057 HOH A O   
5879 O  O   . HOH Q .   ? 0.16900 0.13630 0.31050 -0.01270 0.00150  0.04190  2058 HOH A O   
5880 O  O   . HOH Q .   ? 0.39180 0.42400 0.44560 0.01590  -0.00280 0.00150  2059 HOH A O   
5881 O  O   . HOH Q .   ? 0.24070 0.19430 0.24340 -0.02970 0.04900  0.00640  2060 HOH A O   
5882 O  O   . HOH Q .   ? 0.55430 0.61220 0.62650 -0.07820 0.13660  -0.02290 2061 HOH A O   
5883 O  O   . HOH Q .   ? 0.30830 0.14090 0.15990 0.01220  0.01140  0.00020  2062 HOH A O   
5884 O  O   . HOH Q .   ? 0.15390 0.29130 0.23480 -0.03660 0.02880  -0.05730 2063 HOH A O   
5885 O  O   . HOH Q .   ? 0.44310 0.37900 0.54120 -0.02470 -0.08030 0.03280  2064 HOH A O   
5886 O  O   . HOH Q .   ? 0.37200 0.24230 0.24860 0.06660  0.13060  0.02150  2065 HOH A O   
5887 O  O   . HOH Q .   ? 0.34230 0.26640 0.36620 -0.08650 0.02680  0.02280  2066 HOH A O   
5888 O  O   . HOH Q .   ? 0.35930 0.26690 0.33190 -0.10200 -0.06870 0.02170  2067 HOH A O   
5889 O  O   . HOH Q .   ? 0.28720 0.29340 0.34390 0.07590  -0.03730 0.04730  2068 HOH A O   
5890 O  O   . HOH Q .   ? 0.34460 0.37710 0.35200 -0.10510 0.01300  -0.10520 2069 HOH A O   
5891 O  O   . HOH Q .   ? 0.37260 0.29500 0.30770 -0.03410 -0.01630 -0.06160 2070 HOH A O   
5892 O  O   . HOH Q .   ? 0.14100 0.16850 0.21810 0.00520  0.00100  -0.01240 2071 HOH A O   
5893 O  O   . HOH Q .   ? 0.12470 0.12770 0.21230 -0.01660 0.01140  0.01070  2072 HOH A O   
5894 O  O   . HOH Q .   ? 0.30260 0.24950 0.41070 0.06990  0.15860  0.05320  2073 HOH A O   
5895 O  O   . HOH Q .   ? 0.12080 0.12820 0.14760 -0.01440 0.01440  -0.01090 2074 HOH A O   
5896 O  O   . HOH Q .   ? 0.21210 0.23800 0.23660 0.00720  -0.03800 -0.04940 2075 HOH A O   
5897 O  O   . HOH Q .   ? 0.14800 0.15270 0.20740 0.00150  0.02210  -0.00050 2076 HOH A O   
5898 O  O   . HOH Q .   ? 0.32420 0.34410 0.26860 -0.02060 -0.04950 0.00380  2077 HOH A O   
5899 O  O   . HOH Q .   ? 0.38800 0.39540 0.39900 0.10260  0.09920  0.03410  2078 HOH A O   
5900 O  O   . HOH Q .   ? 0.12360 0.15310 0.15190 -0.01110 0.00840  -0.01350 2079 HOH A O   
5901 O  O   . HOH Q .   ? 0.47180 0.48950 0.53820 -0.04000 -0.07380 0.09410  2080 HOH A O   
5902 O  O   . HOH Q .   ? 0.39500 0.49410 0.42710 -0.06130 0.04690  0.15410  2081 HOH A O   
5903 O  O   . HOH Q .   ? 0.49520 0.41590 0.35800 -0.00760 -0.10040 -0.06010 2082 HOH A O   
5904 O  O   . HOH Q .   ? 0.51810 0.27830 0.27680 0.12940  0.17050  0.05750  2083 HOH A O   
5905 O  O   . HOH Q .   ? 0.36530 0.28890 0.36430 -0.00740 -0.03450 -0.09000 2084 HOH A O   
5906 O  O   . HOH Q .   ? 0.58770 0.53530 0.50840 -0.02910 -0.03000 0.00000  2085 HOH A O   
5907 O  O   . HOH Q .   ? 0.14200 0.18990 0.19190 0.00640  0.01810  -0.00840 2086 HOH A O   
5908 O  O   . HOH Q .   ? 0.37790 0.59960 0.60000 0.06350  -0.05040 0.02310  2087 HOH A O   
5909 O  O   . HOH Q .   ? 0.20700 0.33220 0.29360 -0.00300 -0.02680 0.07380  2088 HOH A O   
5910 O  O   . HOH Q .   ? 0.16370 0.27900 0.22130 -0.01970 0.01490  0.01820  2089 HOH A O   
5911 O  O   . HOH Q .   ? 0.37620 0.42710 0.40500 0.06230  -0.03960 0.07830  2090 HOH A O   
5912 O  O   . HOH Q .   ? 0.31500 0.40410 0.33650 0.09580  0.05560  0.04360  2091 HOH A O   
5913 O  O   . HOH Q .   ? 0.34570 0.41480 0.37100 -0.02460 0.08760  0.00050  2092 HOH A O   
5914 O  O   . HOH Q .   ? 0.14640 0.15310 0.13140 -0.01370 -0.00920 -0.02490 2093 HOH A O   
5915 O  O   . HOH Q .   ? 0.45230 0.30450 0.34990 -0.04100 -0.00240 -0.03700 2094 HOH A O   
5916 O  O   . HOH Q .   ? 0.36370 0.21780 0.26020 -0.03460 0.01600  0.03430  2095 HOH A O   
5917 O  O   . HOH Q .   ? 0.23300 0.35520 0.29590 -0.00730 0.03950  -0.04260 2096 HOH A O   
5918 O  O   . HOH Q .   ? 0.16980 0.22220 0.23640 0.00060  -0.01380 -0.06950 2097 HOH A O   
5919 O  O   . HOH Q .   ? 0.39610 0.42770 0.42980 -0.01070 -0.02850 -0.00180 2098 HOH A O   
5920 O  O   . HOH Q .   ? 0.43480 0.43610 0.46070 -0.01500 -0.01470 -0.00630 2099 HOH A O   
5921 O  O   . HOH Q .   ? 0.47250 0.53780 0.41630 0.04050  -0.02410 0.03460  2100 HOH A O   
5922 O  O   . HOH Q .   ? 0.39850 0.18220 0.30220 -0.02930 -0.05550 -0.08550 2101 HOH A O   
5923 O  O   . HOH Q .   ? 0.31690 0.37240 0.41090 0.05890  0.03750  -0.08460 2102 HOH A O   
5924 O  O   . HOH Q .   ? 0.26200 0.30350 0.20950 0.04160  0.02280  -0.05720 2103 HOH A O   
5925 O  O   . HOH Q .   ? 0.31100 0.46710 0.28040 -0.03950 -0.07990 -0.00160 2104 HOH A O   
5926 O  O   . HOH Q .   ? 0.34260 0.29270 0.31860 -0.10240 0.00480  0.08150  2105 HOH A O   
5927 O  O   . HOH Q .   ? 0.49450 0.35670 0.34940 0.01520  0.16010  0.02070  2106 HOH A O   
5928 O  O   . HOH Q .   ? 0.46070 0.39610 0.49550 -0.03810 0.11980  -0.01820 2107 HOH A O   
5929 O  O   . HOH Q .   ? 0.14500 0.26450 0.26300 -0.04190 0.04500  -0.07370 2108 HOH A O   
5930 O  O   . HOH Q .   ? 0.22050 0.16680 0.20560 0.00220  0.03790  0.00520  2109 HOH A O   
5931 O  O   . HOH Q .   ? 0.29420 0.26210 0.28400 0.03640  0.02370  0.12360  2110 HOH A O   
5932 O  O   . HOH Q .   ? 0.16030 0.15140 0.22330 0.01130  0.03250  0.00880  2111 HOH A O   
5933 O  O   . HOH Q .   ? 0.41960 0.32400 0.26050 0.10630  -0.06950 -0.06510 2112 HOH A O   
5934 O  O   . HOH Q .   ? 0.22150 0.22810 0.14560 0.06060  0.00910  0.02960  2113 HOH A O   
5935 O  O   . HOH Q .   ? 0.13840 0.21760 0.18430 -0.00960 0.00500  -0.01010 2114 HOH A O   
5936 O  O   . HOH Q .   ? 0.21240 0.20350 0.22220 -0.03900 -0.00720 -0.03590 2115 HOH A O   
5937 O  O   . HOH Q .   ? 0.20470 0.39730 0.40060 -0.03200 -0.01400 0.02620  2116 HOH A O   
5938 O  O   . HOH Q .   ? 0.10420 0.18620 0.16900 -0.01530 -0.00970 -0.01010 2117 HOH A O   
5939 O  O   . HOH Q .   ? 0.25590 0.42350 0.28080 0.03600  -0.06330 -0.05110 2118 HOH A O   
5940 O  O   . HOH Q .   ? 0.19710 0.23180 0.34210 0.01170  0.04920  0.03090  2119 HOH A O   
5941 O  O   . HOH Q .   ? 0.38420 0.29080 0.26730 -0.08460 0.08400  0.00940  2120 HOH A O   
5942 O  O   . HOH Q .   ? 0.24210 0.30610 0.27300 -0.07430 0.05600  0.03420  2121 HOH A O   
5943 O  O   . HOH Q .   ? 0.33450 0.43510 0.25850 -0.09950 -0.02480 -0.00740 2122 HOH A O   
5944 O  O   . HOH Q .   ? 0.11510 0.12390 0.12540 0.01330  -0.00580 -0.00930 2123 HOH A O   
5945 O  O   . HOH Q .   ? 0.12720 0.15450 0.18360 -0.01220 -0.00020 0.00110  2124 HOH A O   
5946 O  O   . HOH Q .   ? 0.28740 0.26490 0.28100 -0.04640 0.00510  -0.01720 2125 HOH A O   
5947 O  O   . HOH Q .   ? 0.26730 0.33050 0.20880 -0.09450 0.07560  -0.02650 2126 HOH A O   
5948 O  O   . HOH Q .   ? 0.21890 0.25570 0.22260 0.06600  0.02750  0.00750  2127 HOH A O   
5949 O  O   . HOH Q .   ? 0.47410 0.44250 0.31090 0.03800  0.12300  -0.00490 2128 HOH A O   
5950 O  O   . HOH Q .   ? 0.20920 0.24020 0.30930 -0.06690 0.03830  -0.05540 2129 HOH A O   
5951 O  O   . HOH Q .   ? 0.15140 0.14970 0.16760 0.02190  -0.01010 -0.00980 2130 HOH A O   
5952 O  O   . HOH Q .   ? 0.46600 0.46250 0.41820 -0.06870 0.02190  0.11030  2131 HOH A O   
5953 O  O   . HOH Q .   ? 0.41860 0.42250 0.42400 -0.03190 -0.01780 -0.00190 2132 HOH A O   
5954 O  O   . HOH Q .   ? 0.27010 0.48420 0.34440 -0.10000 0.04070  0.14710  2133 HOH A O   
5955 O  O   . HOH Q .   ? 0.11060 0.10180 0.14060 0.00290  0.00900  -0.01480 2134 HOH A O   
5956 O  O   . HOH Q .   ? 0.37210 0.47990 0.39280 -0.03560 0.13590  0.11070  2135 HOH A O   
5957 O  O   . HOH Q .   ? 0.33060 0.40310 0.33760 -0.01730 0.00370  -0.05240 2136 HOH A O   
5958 O  O   . HOH Q .   ? 0.30620 0.33650 0.38170 -0.07980 -0.11670 -0.01990 2137 HOH A O   
5959 O  O   . HOH Q .   ? 0.38310 0.45710 0.29680 0.07800  -0.06230 -0.01960 2138 HOH A O   
5960 O  O   . HOH Q .   ? 0.26180 0.38630 0.37030 -0.04000 -0.05700 0.02150  2139 HOH A O   
5961 O  O   . HOH Q .   ? 0.19200 0.15890 0.26890 0.02090  -0.01730 0.01310  2140 HOH A O   
5962 O  O   . HOH Q .   ? 0.24860 0.32670 0.24840 -0.01610 0.03370  -0.01710 2141 HOH A O   
5963 O  O   . HOH Q .   ? 0.55750 0.46890 0.53200 -0.11640 -0.06290 -0.00810 2142 HOH A O   
5964 O  O   . HOH Q .   ? 0.18200 0.17100 0.22560 0.01750  -0.00790 -0.01980 2143 HOH A O   
5965 O  O   . HOH Q .   ? 0.30860 0.48860 0.30760 -0.10660 0.06100  -0.10950 2144 HOH A O   
5966 O  O   . HOH Q .   ? 0.16270 0.20040 0.40470 0.01360  -0.04250 -0.02230 2145 HOH A O   
5967 O  O   . HOH Q .   ? 0.27860 0.42770 0.18830 0.13930  -0.03160 -0.03130 2146 HOH A O   
5968 O  O   . HOH Q .   ? 0.45500 0.45020 0.41440 -0.12770 -0.01830 0.05000  2147 HOH A O   
5969 O  O   . HOH Q .   ? 0.28200 0.19870 0.37940 0.00360  0.03900  -0.02840 2148 HOH A O   
5970 O  O   . HOH Q .   ? 0.32620 0.32820 0.24340 -0.03550 0.02280  0.01920  2149 HOH A O   
5971 O  O   . HOH Q .   ? 0.19620 0.14220 0.25230 -0.02980 0.00880  0.03350  2150 HOH A O   
5972 O  O   . HOH Q .   ? 0.47910 0.22440 0.26310 -0.04340 0.04000  0.00690  2151 HOH A O   
5973 O  O   . HOH Q .   ? 0.39900 0.44660 0.41630 -0.06110 0.04960  0.10830  2152 HOH A O   
5974 O  O   . HOH Q .   ? 0.32970 0.31090 0.31670 0.06810  -0.02880 0.03820  2153 HOH A O   
5975 O  O   . HOH Q .   ? 0.39650 0.39320 0.39590 -0.00650 0.00660  0.00050  2154 HOH A O   
5976 O  O   . HOH Q .   ? 0.33660 0.33000 0.46940 0.05710  0.09470  -0.08040 2155 HOH A O   
5977 O  O   . HOH Q .   ? 0.21360 0.30700 0.30730 -0.02790 0.00310  0.05060  2156 HOH A O   
5978 O  O   . HOH Q .   ? 0.27470 0.22140 0.30910 -0.00790 -0.01140 -0.11520 2157 HOH A O   
5979 O  O   . HOH Q .   ? 0.28890 0.15440 0.25020 0.03180  0.03400  0.04390  2158 HOH A O   
5980 O  O   . HOH Q .   ? 0.20390 0.16840 0.20010 0.04280  -0.05900 -0.02650 2159 HOH A O   
5981 O  O   . HOH Q .   ? 0.13370 0.15700 0.15130 0.01030  -0.00210 -0.00210 2160 HOH A O   
5982 O  O   . HOH Q .   ? 0.29110 0.39100 0.28960 -0.06050 0.09420  -0.05280 2161 HOH A O   
5983 O  O   . HOH Q .   ? 0.35700 0.38720 0.38520 0.00730  0.00330  -0.02220 2162 HOH A O   
5984 O  O   . HOH Q .   ? 0.29620 0.30870 0.34760 -0.02480 -0.10090 -0.09110 2163 HOH A O   
5985 O  O   . HOH Q .   ? 0.53970 0.48350 0.39680 0.07070  -0.14710 0.05280  2164 HOH A O   
5986 O  O   . HOH Q .   ? 0.38710 0.49670 0.37040 -0.05500 0.01700  -0.04320 2165 HOH A O   
5987 O  O   . HOH Q .   ? 0.17980 0.46710 0.25210 0.08600  -0.01160 0.05380  2166 HOH A O   
5988 O  O   . HOH Q .   ? 0.29660 0.34590 0.22000 0.01840  -0.06770 0.05030  2167 HOH A O   
5989 O  O   . HOH Q .   ? 0.12110 0.13230 0.25620 -0.00640 0.00500  0.02160  2168 HOH A O   
5990 O  O   . HOH Q .   ? 0.21280 0.24250 0.39810 0.02800  -0.03410 0.08320  2169 HOH A O   
5991 O  O   . HOH Q .   ? 0.11540 0.16050 0.18760 -0.00080 -0.01500 -0.01690 2170 HOH A O   
5992 O  O   . HOH Q .   ? 0.12130 0.16540 0.14900 -0.01280 0.00690  -0.04240 2171 HOH A O   
5993 O  O   . HOH Q .   ? 0.17820 0.34970 0.15880 0.02010  0.00990  -0.05320 2172 HOH A O   
5994 O  O   . HOH Q .   ? 0.13780 0.23490 0.21080 0.00880  0.00390  -0.02560 2173 HOH A O   
5995 O  O   . HOH Q .   ? 0.39760 0.54460 0.39820 0.08940  0.07810  -0.05080 2174 HOH A O   
5996 O  O   . HOH Q .   ? 0.25710 0.21360 0.19890 -0.01750 -0.01200 0.05730  2175 HOH A O   
5997 O  O   . HOH Q .   ? 0.12280 0.12790 0.15910 -0.00870 -0.00140 0.00450  2176 HOH A O   
5998 O  O   . HOH Q .   ? 0.21890 0.23040 0.26430 -0.01950 0.00640  0.07460  2177 HOH A O   
5999 O  O   . HOH Q .   ? 0.26370 0.37770 0.20780 0.05940  0.09410  -0.00230 2178 HOH A O   
6000 O  O   . HOH Q .   ? 0.39590 0.40720 0.39410 0.00720  0.01270  0.00180  2179 HOH A O   
6001 O  O   . HOH Q .   ? 0.26040 0.38670 0.36960 0.09450  0.10260  0.08200  2180 HOH A O   
6002 O  O   . HOH Q .   ? 0.14350 0.12170 0.16430 -0.00060 0.01670  0.00140  2181 HOH A O   
6003 O  O   . HOH Q .   ? 0.15630 0.14640 0.21330 -0.02120 0.00400  0.02390  2182 HOH A O   
6004 O  O   . HOH Q .   ? 0.32340 0.37520 0.41300 0.00750  -0.01880 -0.02190 2183 HOH A O   
6005 O  O   . HOH Q .   ? 0.30060 0.16360 0.26740 -0.01110 -0.00350 0.03560  2184 HOH A O   
6006 O  O   . HOH Q .   ? 0.58560 0.52890 0.51100 0.07080  0.08660  -0.02180 2185 HOH A O   
6007 O  O   . HOH Q .   ? 0.25000 0.22490 0.22920 -0.03400 0.02160  0.03280  2186 HOH A O   
6008 O  O   . HOH Q .   ? 0.20850 0.18730 0.15650 -0.01560 0.02900  0.00940  2187 HOH A O   
6009 O  O   . HOH Q .   ? 0.33580 0.26010 0.35350 0.00720  0.06910  0.01370  2188 HOH A O   
6010 O  O   . HOH Q .   ? 0.42480 0.35370 0.48990 -0.17350 -0.02100 -0.01070 2189 HOH A O   
6011 O  O   . HOH Q .   ? 0.25080 0.30360 0.34610 0.04660  0.03540  0.03860  2190 HOH A O   
6012 O  O   . HOH Q .   ? 0.19840 0.16750 0.30700 -0.01470 0.04470  0.03580  2191 HOH A O   
6013 O  O   . HOH Q .   ? 0.35800 0.27490 0.45610 -0.11190 0.03100  0.04110  2192 HOH A O   
6014 O  O   . HOH Q .   ? 0.19780 0.16490 0.30340 -0.01990 -0.00390 0.04890  2193 HOH A O   
6015 O  O   . HOH Q .   ? 0.29710 0.27600 0.35850 0.06280  0.04060  0.01740  2194 HOH A O   
6016 O  O   . HOH Q .   ? 0.52120 0.31650 0.40720 0.04080  -0.06190 -0.00140 2195 HOH A O   
6017 O  O   . HOH Q .   ? 0.37690 0.40170 0.40100 -0.01130 -0.00870 -0.00280 2196 HOH A O   
6018 O  O   . HOH Q .   ? 0.18820 0.16470 0.20730 -0.01320 0.01470  -0.02740 2197 HOH A O   
6019 O  O   . HOH Q .   ? 0.42030 0.49970 0.38400 0.06800  0.10910  0.01080  2198 HOH A O   
6020 O  O   . HOH Q .   ? 0.22930 0.39250 0.28920 -0.01560 -0.09770 -0.02140 2199 HOH A O   
6021 O  O   . HOH Q .   ? 0.26290 0.33290 0.34710 -0.01810 0.07380  0.16230  2200 HOH A O   
6022 O  O   . HOH Q .   ? 0.38960 0.44990 0.40870 0.07210  0.01820  0.02150  2201 HOH A O   
6023 O  O   . HOH Q .   ? 0.19960 0.12820 0.21050 -0.02880 0.01060  -0.02110 2202 HOH A O   
6024 O  O   . HOH Q .   ? 0.21860 0.18820 0.29280 0.01680  -0.05450 -0.01640 2203 HOH A O   
6025 O  O   . HOH Q .   ? 0.27760 0.47360 0.42880 -0.03480 0.03890  -0.01410 2204 HOH A O   
6026 O  O   . HOH Q .   ? 0.40540 0.29670 0.37120 -0.00520 0.07630  -0.00690 2205 HOH A O   
6027 O  O   . HOH Q .   ? 0.19520 0.32190 0.35260 0.01320  0.01940  -0.02170 2206 HOH A O   
6028 O  O   . HOH Q .   ? 0.28630 0.38150 0.34330 0.09490  0.02800  -0.04990 2207 HOH A O   
6029 O  O   . HOH Q .   ? 0.41350 0.42110 0.41650 -0.02030 -0.06960 -0.01410 2208 HOH A O   
6030 O  O   . HOH Q .   ? 0.16100 0.14090 0.18260 -0.00030 -0.02530 0.00500  2209 HOH A O   
6031 O  O   . HOH Q .   ? 0.39150 0.44720 0.43470 0.00570  -0.03660 0.00610  2210 HOH A O   
6032 O  O   . HOH Q .   ? 0.17540 0.28090 0.39420 -0.00110 0.07240  -0.02630 2211 HOH A O   
6033 O  O   . HOH Q .   ? 0.35390 0.26040 0.42720 -0.06140 0.11180  -0.11800 2212 HOH A O   
6034 O  O   . HOH Q .   ? 0.34730 0.26570 0.19990 -0.04380 -0.04900 -0.02380 2213 HOH A O   
6035 O  O   . HOH Q .   ? 0.36840 0.37750 0.29790 0.00110  0.09170  0.10210  2214 HOH A O   
6036 O  O   . HOH Q .   ? 0.38460 0.50160 0.40540 0.10270  -0.05210 -0.07280 2215 HOH A O   
6037 O  O   . HOH Q .   ? 0.11060 0.16260 0.17090 -0.00490 -0.01050 -0.00430 2216 HOH A O   
6038 O  O   . HOH Q .   ? 0.23660 0.44870 0.36360 -0.01520 0.12490  -0.02130 2217 HOH A O   
6039 O  O   . HOH Q .   ? 0.31440 0.31830 0.26010 -0.04810 0.05030  -0.06980 2218 HOH A O   
6040 O  O   . HOH Q .   ? 0.27990 0.31150 0.25010 -0.07310 0.03800  0.04960  2219 HOH A O   
6041 O  O   . HOH Q .   ? 0.22260 0.48770 0.31820 -0.01550 -0.05760 -0.04870 2220 HOH A O   
6042 O  O   . HOH Q .   ? 0.23320 0.54600 0.30350 -0.05620 -0.08400 0.00080  2221 HOH A O   
6043 O  O   . HOH Q .   ? 0.42880 0.42510 0.32290 -0.02980 0.15730  -0.11300 2222 HOH A O   
6044 O  O   . HOH Q .   ? 0.25210 0.33280 0.32210 0.09990  0.07220  0.05400  2223 HOH A O   
6045 O  O   . HOH Q .   ? 0.13390 0.17130 0.16280 0.01830  -0.01310 -0.01990 2224 HOH A O   
6046 O  O   . HOH Q .   ? 0.20340 0.27900 0.38510 -0.02370 0.07540  -0.05290 2225 HOH A O   
6047 O  O   . HOH Q .   ? 0.19970 0.28810 0.29990 0.03900  -0.07630 -0.03970 2226 HOH A O   
6048 O  O   . HOH Q .   ? 0.42420 0.42300 0.47890 -0.02350 -0.06790 -0.08990 2227 HOH A O   
6049 O  O   . HOH Q .   ? 0.56170 0.42720 0.52120 0.05890  0.04920  0.01110  2228 HOH A O   
6050 O  O   . HOH Q .   ? 0.43730 0.27000 0.44410 -0.01700 0.03950  0.08880  2229 HOH A O   
6051 O  O   . HOH Q .   ? 0.44570 0.43000 0.42820 0.02380  0.03150  -0.00340 2230 HOH A O   
6052 O  O   . HOH Q .   ? 0.17410 0.13790 0.14610 0.01140  0.00810  0.00510  2231 HOH A O   
6053 O  O   . HOH Q .   ? 0.63210 0.67210 0.63610 -0.00160 -0.05980 0.00560  2232 HOH A O   
6054 O  O   . HOH Q .   ? 0.28430 0.31330 0.22740 0.05870  -0.05410 -0.03020 2233 HOH A O   
6055 O  O   . HOH Q .   ? 0.24930 0.43310 0.39390 -0.03270 0.02670  0.00350  2234 HOH A O   
6056 O  O   . HOH Q .   ? 0.35650 0.30200 0.35240 0.02130  -0.05320 0.08420  2235 HOH A O   
6057 O  O   . HOH Q .   ? 0.43940 0.54160 0.44970 -0.10650 -0.04690 0.06030  2236 HOH A O   
6058 O  O   . HOH Q .   ? 0.32490 0.42410 0.27750 -0.10970 -0.02600 0.05090  2237 HOH A O   
6059 O  O   . HOH Q .   ? 0.39150 0.49040 0.33060 -0.00240 -0.05340 0.00140  2238 HOH A O   
6060 O  O   . HOH Q .   ? 0.34640 0.33160 0.30740 0.05770  0.02200  0.07010  2239 HOH A O   
6061 O  O   . HOH Q .   ? 0.43310 0.26670 0.25640 -0.02170 -0.10310 -0.02080 2240 HOH A O   
6062 O  O   . HOH Q .   ? 0.21460 0.22480 0.35900 -0.04380 -0.00020 0.06300  2241 HOH A O   
6063 O  O   . HOH Q .   ? 0.31240 0.20520 0.25680 -0.03800 -0.02070 -0.06280 2242 HOH A O   
6064 O  O   . HOH Q .   ? 0.45640 0.44330 0.36630 0.00700  -0.05830 -0.12760 2243 HOH A O   
6065 O  O   . HOH Q .   ? 0.57480 0.54550 0.43760 -0.03680 0.04700  -0.05670 2244 HOH A O   
6066 O  O   . HOH Q .   ? 0.38200 0.34210 0.27080 0.07230  -0.03880 -0.03140 2245 HOH A O   
6067 O  O   . HOH Q .   ? 0.40870 0.47980 0.42030 0.01930  0.09790  0.02370  2246 HOH A O   
6068 O  O   . HOH Q .   ? 0.34740 0.28890 0.40420 0.02650  0.09960  0.05710  2247 HOH A O   
6069 O  O   . HOH Q .   ? 0.33130 0.42070 0.43160 -0.08610 -0.02310 -0.00890 2248 HOH A O   
6070 O  O   . HOH Q .   ? 0.34860 0.15050 0.21650 -0.03450 0.09110  -0.04490 2249 HOH A O   
6071 O  O   . HOH Q .   ? 0.21110 0.15720 0.25610 -0.02570 0.01710  -0.00510 2250 HOH A O   
6072 O  O   . HOH Q .   ? 0.22390 0.21780 0.27670 0.03420  0.10560  0.00350  2251 HOH A O   
6073 O  O   . HOH Q .   ? 0.39880 0.43670 0.53930 0.09890  -0.02730 -0.06220 2252 HOH A O   
6074 O  O   . HOH Q .   ? 0.26980 0.38610 0.37820 -0.07900 -0.04560 -0.10730 2253 HOH A O   
6075 O  O   . HOH Q .   ? 0.47640 0.44180 0.42530 -0.01050 0.00050  0.01030  2254 HOH A O   
6076 O  O   . HOH Q .   ? 0.39980 0.41590 0.50110 0.18870  -0.00770 0.09320  2255 HOH A O   
6077 O  O   . HOH Q .   ? 0.19140 0.46170 0.24980 -0.08180 -0.06730 -0.04220 2256 HOH A O   
6078 O  O   . HOH Q .   ? 0.29350 0.21480 0.40140 0.04500  -0.08710 0.06420  2257 HOH A O   
6079 O  O   . HOH Q .   ? 0.46740 0.44260 0.45230 0.01390  0.01350  -0.01090 2258 HOH A O   
6080 O  O   . HOH Q .   ? 0.15110 0.13280 0.19830 0.00730  0.02020  -0.00320 2259 HOH A O   
6081 O  O   . HOH Q .   ? 0.37800 0.43870 0.52440 -0.04010 0.02640  -0.03630 2260 HOH A O   
6082 O  O   . HOH Q .   ? 0.32090 0.30320 0.42070 0.06080  -0.00590 0.03130  2261 HOH A O   
6083 O  O   . HOH Q .   ? 0.22310 0.25640 0.28000 -0.05330 0.04980  -0.09060 2262 HOH A O   
6084 O  O   . HOH Q .   ? 0.35120 0.25590 0.29540 -0.01380 -0.04140 -0.04970 2263 HOH A O   
6085 O  O   . HOH Q .   ? 0.27120 0.42300 0.30670 0.13390  -0.04040 0.06070  2264 HOH A O   
6086 O  O   . HOH Q .   ? 0.32350 0.24780 0.33980 0.02640  -0.04100 -0.10280 2265 HOH A O   
6087 O  O   . HOH Q .   ? 0.19400 0.13990 0.22000 0.03830  -0.02090 -0.03150 2266 HOH A O   
6088 O  O   . HOH Q .   ? 0.24190 0.26130 0.36160 -0.00820 -0.00620 -0.13220 2267 HOH A O   
6089 O  O   . HOH Q .   ? 0.34280 0.23730 0.32560 -0.08600 0.03750  0.01640  2268 HOH A O   
6090 O  O   . HOH Q .   ? 0.18260 0.21800 0.23350 0.07730  -0.02310 -0.04910 2269 HOH A O   
6091 O  O   . HOH Q .   ? 0.40520 0.44730 0.30990 0.13380  -0.03450 0.02760  2270 HOH A O   
6092 O  O   . HOH Q .   ? 0.45330 0.39370 0.28970 -0.00370 -0.09050 0.04230  2271 HOH A O   
6093 O  O   . HOH Q .   ? 0.38010 0.48350 0.37590 0.03850  -0.03940 -0.04430 2272 HOH A O   
6094 O  O   . HOH Q .   ? 0.14760 0.13460 0.15680 -0.01110 0.00360  0.00420  2273 HOH A O   
6095 O  O   . HOH Q .   ? 0.17640 0.25890 0.16810 -0.02000 0.03550  -0.01160 2274 HOH A O   
6096 O  O   . HOH Q .   ? 0.28170 0.22770 0.45540 -0.03440 -0.02180 -0.02220 2275 HOH A O   
6097 O  O   . HOH Q .   ? 0.48950 0.53450 0.45380 -0.05500 -0.09140 0.02890  2276 HOH A O   
6098 O  O   . HOH Q .   ? 0.41840 0.33530 0.35970 0.00570  -0.01070 0.06780  2277 HOH A O   
6099 O  O   . HOH Q .   ? 0.50790 0.49960 0.50490 0.03350  0.13500  0.01670  2278 HOH A O   
6100 O  O   . HOH Q .   ? 0.40680 0.46790 0.42210 0.00280  -0.00310 0.04850  2279 HOH A O   
6101 O  O   . HOH Q .   ? 0.38120 0.46980 0.43090 0.02240  0.04420  0.09410  2280 HOH A O   
6102 O  O   . HOH Q .   ? 0.43510 0.41350 0.49780 -0.07930 0.14180  -0.14210 2281 HOH A O   
6103 O  O   . HOH Q .   ? 0.71120 0.32580 0.36610 -0.00370 0.00490  0.00720  2282 HOH A O   
6104 O  O   . HOH Q .   ? 0.53110 0.47740 0.61510 0.01570  -0.08200 -0.00930 2283 HOH A O   
6105 O  O   . HOH Q .   ? 0.52070 0.46440 0.52060 -0.01450 0.06730  -0.00540 2284 HOH A O   
6106 O  O   . HOH Q .   ? 0.59160 0.60420 0.59550 -0.03060 0.05740  -0.04550 2285 HOH A O   
6107 O  O   . HOH Q .   ? 0.21390 0.21050 0.34610 -0.03810 0.01340  -0.02450 2286 HOH A O   
6108 O  O   . HOH Q .   ? 0.36970 0.34510 0.30050 -0.01370 -0.10550 0.08960  2287 HOH A O   
6109 O  O   . HOH Q .   ? 0.38250 0.26870 0.38850 0.17240  0.04450  0.06960  2288 HOH A O   
6110 O  O   . HOH Q .   ? 0.39050 0.46980 0.19440 0.01060  0.00070  -0.00690 2289 HOH A O   
6111 O  O   . HOH Q .   ? 0.38670 0.26820 0.38130 0.13900  -0.08910 -0.07620 2290 HOH A O   
6112 O  O   . HOH Q .   ? 0.43850 0.35700 0.50900 -0.03350 -0.05740 0.06930  2291 HOH A O   
6113 O  O   . HOH Q .   ? 0.43650 0.46000 0.49170 0.18140  0.08210  -0.02180 2292 HOH A O   
6114 O  O   . HOH Q .   ? 0.40440 0.27610 0.32580 -0.13500 0.03790  0.03180  2293 HOH A O   
6115 O  O   . HOH Q .   ? 0.37660 0.38430 0.47430 0.05300  -0.00800 -0.00010 2294 HOH A O   
6116 O  O   . HOH Q .   ? 0.38930 0.43920 0.39710 0.01300  -0.02240 0.05580  2295 HOH A O   
6117 O  O   . HOH Q .   ? 0.46640 0.45120 0.49210 0.12060  0.04370  0.08130  2296 HOH A O   
6118 O  O   . HOH Q .   ? 0.37250 0.25120 0.50450 -0.01680 0.18390  -0.09060 2297 HOH A O   
6119 O  O   . HOH Q .   ? 0.33870 0.33210 0.46790 0.06170  0.13230  0.05070  2298 HOH A O   
6120 O  O   . HOH Q .   ? 0.53990 0.52050 0.51720 -0.02970 -0.05970 -0.01480 2299 HOH A O   
6121 O  O   . HOH Q .   ? 0.26820 0.40310 0.27290 0.06440  -0.01730 -0.02100 2300 HOH A O   
6122 O  O   . HOH Q .   ? 0.20610 0.28900 0.56420 -0.07880 0.00340  0.09010  2301 HOH A O   
6123 O  O   . HOH Q .   ? 0.50550 0.39460 0.50500 0.14560  0.01040  -0.03380 2302 HOH A O   
6124 O  O   . HOH Q .   ? 0.25860 0.28750 0.29450 0.02000  0.00140  -0.04840 2303 HOH A O   
6125 O  O   . HOH Q .   ? 0.19580 0.19330 0.27610 -0.04260 0.00960  -0.01720 2304 HOH A O   
6126 O  O   . HOH Q .   ? 0.40340 0.40080 0.39380 -0.01340 -0.00370 -0.00980 2305 HOH A O   
6127 O  O   . HOH Q .   ? 0.36110 0.45780 0.40030 0.00730  -0.10860 0.03760  2306 HOH A O   
6128 O  O   . HOH Q .   ? 0.31920 0.49580 0.43790 0.06440  -0.08490 0.00350  2307 HOH A O   
6129 O  O   . HOH Q .   ? 0.43170 0.59090 0.41520 -0.04460 -0.10470 0.02790  2308 HOH A O   
6130 O  O   . HOH Q .   ? 0.23070 0.47980 0.39050 -0.06030 -0.06170 0.06700  2309 HOH A O   
6131 O  O   . HOH Q .   ? 0.43530 0.42790 0.43810 0.00260  -0.01020 0.00870  2310 HOH A O   
6132 O  O   . HOH Q .   ? 0.30290 0.43730 0.37450 0.06840  0.10560  -0.05640 2311 HOH A O   
6133 O  O   . HOH Q .   ? 0.42240 0.44730 0.41970 0.07830  -0.00200 0.00120  2312 HOH A O   
6134 O  O   . HOH Q .   ? 0.35060 0.42560 0.52710 0.05320  -0.11850 -0.12000 2313 HOH A O   
6135 O  O   . HOH Q .   ? 0.44790 0.29700 0.53900 -0.03410 0.04170  0.06120  2314 HOH A O   
6136 O  O   . HOH Q .   ? 0.20700 0.16760 0.37500 0.02210  0.01710  -0.03610 2315 HOH A O   
6137 O  O   . HOH Q .   ? 0.29400 0.40640 0.49140 0.04510  0.03810  -0.08030 2316 HOH A O   
6138 O  O   . HOH Q .   ? 0.41240 0.50520 0.35070 0.01730  -0.11030 -0.02610 2317 HOH A O   
6139 O  O   . HOH Q .   ? 0.42510 0.36840 0.53360 0.02040  -0.02250 0.10530  2318 HOH A O   
6140 O  O   . HOH Q .   ? 0.28420 0.28500 0.28920 -0.11490 -0.02640 -0.11530 2319 HOH A O   
6141 O  O   . HOH Q .   ? 0.40890 0.42000 0.45410 -0.00810 -0.00400 -0.00540 2320 HOH A O   
6142 O  O   . HOH Q .   ? 0.46810 0.32750 0.46840 -0.09290 -0.00110 0.11280  2321 HOH A O   
6143 O  O   . HOH Q .   ? 0.41680 0.45280 0.46630 -0.05230 -0.03760 -0.04480 2322 HOH A O   
6144 O  O   . HOH Q .   ? 0.42970 0.30120 0.46750 0.07000  0.03720  0.10480  2323 HOH A O   
6145 O  O   . HOH Q .   ? 0.19110 0.19620 0.21130 0.01110  -0.00160 -0.02270 2324 HOH A O   
6146 O  O   . HOH Q .   ? 0.31710 0.57820 0.39310 -0.05440 0.06360  -0.00110 2325 HOH A O   
6147 O  O   . HOH Q .   ? 0.38790 0.47860 0.40110 -0.04390 -0.04310 -0.04930 2326 HOH A O   
6148 O  O   . HOH Q .   ? 0.49740 0.44430 0.53660 -0.08590 0.06000  0.01220  2327 HOH A O   
6149 O  O   . HOH Q .   ? 0.28550 0.21820 0.29520 -0.07100 0.04800  -0.03560 2328 HOH A O   
6150 O  O   . HOH Q .   ? 0.44550 0.44060 0.44020 -0.02390 0.01280  0.02160  2329 HOH A O   
6151 O  O   . HOH Q .   ? 0.44000 0.45220 0.44280 0.01010  -0.02040 0.04190  2330 HOH A O   
6152 O  O   . HOH Q .   ? 0.25520 0.26830 0.50890 0.01150  0.10130  -0.01940 2331 HOH A O   
6153 O  O   . HOH Q .   ? 0.37820 0.43250 0.32690 0.00990  0.02420  0.16160  2332 HOH A O   
6154 O  O   . HOH Q .   ? 0.49470 0.49000 0.37780 -0.00230 0.00340  -0.07010 2333 HOH A O   
6155 O  O   . HOH Q .   ? 0.39470 0.39970 0.38820 0.00040  0.00600  0.00210  2334 HOH A O   
6156 O  O   . HOH Q .   ? 0.40120 0.39050 0.39330 -0.00270 -0.00150 -0.01340 2335 HOH A O   
6157 O  O   . HOH Q .   ? 0.31700 0.39330 0.28340 -0.03160 -0.01230 -0.08710 2336 HOH A O   
6158 O  O   . HOH Q .   ? 0.50730 0.42340 0.48990 -0.01470 0.04440  0.01150  2337 HOH A O   
6159 O  O   . HOH Q .   ? 0.47570 0.46430 0.43840 0.11120  -0.01130 -0.04010 2338 HOH A O   
6160 O  O   . HOH Q .   ? 0.34170 0.21270 0.44620 -0.05230 0.08010  -0.03330 2339 HOH A O   
6161 O  O   . HOH Q .   ? 0.48330 0.46220 0.45050 0.04660  -0.04850 -0.07840 2340 HOH A O   
6162 O  O   . HOH Q .   ? 0.44890 0.40310 0.42750 0.03720  0.00750  0.00120  2341 HOH A O   
6163 O  O   . HOH Q .   ? 0.53440 0.36220 0.43370 -0.01900 0.03830  -0.00170 2342 HOH A O   
6164 O  O   . HOH Q .   ? 0.33140 0.34240 0.40400 -0.05240 -0.02860 0.07490  2343 HOH A O   
6165 O  O   . HOH Q .   ? 0.43910 0.44950 0.44140 0.02970  -0.01540 -0.00640 2344 HOH A O   
6166 O  O   . HOH Q .   ? 0.47490 0.39720 0.44110 0.04970  -0.00220 0.16650  2345 HOH A O   
6167 O  O   . HOH Q .   ? 0.35900 0.39620 0.39990 -0.01130 0.01150  0.06200  2346 HOH A O   
6168 O  O   . HOH Q .   ? 0.23620 0.28980 0.22890 0.00520  0.03770  -0.08320 2347 HOH A O   
6169 O  O   . HOH Q .   ? 0.48380 0.29930 0.41100 0.01600  0.04780  -0.05120 2348 HOH A O   
6170 O  O   . HOH Q .   ? 0.29420 0.22530 0.23730 0.04230  0.07260  -0.03480 2349 HOH A O   
6171 O  O   . HOH Q .   ? 0.30140 0.38720 0.47790 -0.07550 -0.04310 0.10400  2350 HOH A O   
6172 O  O   . HOH Q .   ? 0.22850 0.20140 0.31300 -0.01690 0.04430  -0.01840 2351 HOH A O   
6173 O  O   . HOH Q .   ? 0.35830 0.36280 0.47140 -0.05950 0.05870  0.05490  2352 HOH A O   
6174 O  O   . HOH Q .   ? 0.18600 0.33790 0.23200 0.02030  0.06010  0.04360  2353 HOH A O   
6175 O  O   . HOH Q .   ? 0.33540 0.25980 0.24570 -0.12690 -0.04940 0.06430  2354 HOH A O   
6176 O  O   . HOH Q .   ? 0.17690 0.28680 0.24090 0.00550  -0.00170 -0.00220 2355 HOH A O   
6177 O  O   . HOH Q .   ? 0.40430 0.39380 0.38810 0.00970  -0.00650 0.00680  2356 HOH A O   
6178 O  O   . HOH Q .   ? 0.43740 0.44520 0.44160 -0.02790 -0.03580 0.00850  2357 HOH A O   
6179 O  O   . HOH Q .   ? 0.50900 0.55990 0.45560 0.02920  -0.00820 -0.05090 2358 HOH A O   
6180 O  O   . HOH Q .   ? 0.53710 0.55470 0.48820 0.07790  0.02260  0.00180  2359 HOH A O   
6181 O  O   . HOH Q .   ? 0.41190 0.45090 0.38370 0.06220  0.04080  0.06990  2360 HOH A O   
6182 O  O   . HOH Q .   ? 0.28790 0.37950 0.53010 -0.00370 0.08480  0.07360  2361 HOH A O   
6183 O  O   . HOH Q .   ? 0.41400 0.42940 0.43510 -0.05220 0.01670  0.00060  2362 HOH A O   
6184 O  O   . HOH Q .   ? 0.21650 0.30220 0.25450 0.00010  0.04770  0.00010  2363 HOH A O   
6185 O  O   . HOH Q .   ? 0.51670 0.58770 0.51440 -0.04390 -0.01900 0.06470  2364 HOH A O   
6186 O  O   . HOH Q .   ? 0.34760 0.28780 0.28550 -0.13230 0.03390  -0.02710 2365 HOH A O   
6187 O  O   . HOH Q .   ? 0.55700 0.50120 0.58610 0.02940  0.02890  0.04480  2366 HOH A O   
6188 O  O   . HOH Q .   ? 0.30830 0.50700 0.38150 -0.09520 0.04340  0.01510  2367 HOH A O   
6189 O  O   . HOH Q .   ? 0.50080 0.43280 0.38250 -0.05300 0.06440  -0.09380 2368 HOH A O   
6190 O  O   . HOH Q .   ? 0.42720 0.56490 0.52570 0.01630  0.01950  0.01900  2369 HOH A O   
6191 O  O   . HOH Q .   ? 0.44270 0.35800 0.58390 0.13060  0.01320  -0.03340 2370 HOH A O   
6192 O  O   . HOH Q .   ? 0.30060 0.34290 0.33630 -0.09650 0.07210  0.02950  2371 HOH A O   
6193 O  O   . HOH Q .   ? 0.44870 0.58690 0.38350 -0.07680 -0.06450 0.08370  2372 HOH A O   
6194 O  O   . HOH Q .   ? 0.44980 0.41270 0.44370 -0.03360 0.02390  0.01540  2373 HOH A O   
6195 O  O   . HOH Q .   ? 0.41180 0.43350 0.43630 0.00900  0.01600  -0.01510 2374 HOH A O   
6196 O  O   . HOH Q .   ? 0.32200 0.37940 0.45690 -0.08550 -0.06590 0.05690  2375 HOH A O   
6197 O  O   . HOH Q .   ? 0.41030 0.41840 0.52010 -0.02900 -0.03540 0.06050  2376 HOH A O   
6198 O  O   . HOH Q .   ? 0.38870 0.35410 0.30540 -0.13120 0.02890  0.08730  2377 HOH A O   
6199 O  O   . HOH Q .   ? 0.34170 0.49130 0.36780 0.01180  -0.04420 0.07880  2378 HOH A O   
6200 O  O   . HOH Q .   ? 0.40760 0.39720 0.40220 -0.00000 0.00720  -0.00130 2379 HOH A O   
6201 O  O   . HOH Q .   ? 0.13420 0.19740 0.22230 0.01480  -0.03640 -0.00820 2380 HOH A O   
6202 O  O   . HOH Q .   ? 0.25810 0.28400 0.37640 -0.06800 0.04490  -0.00630 2381 HOH A O   
6203 O  O   . HOH Q .   ? 0.36520 0.36430 0.38070 0.01780  -0.01730 -0.01680 2382 HOH A O   
6204 O  O   . HOH Q .   ? 0.44810 0.48800 0.36810 0.02980  0.02030  0.06240  2383 HOH A O   
6205 O  O   . HOH Q .   ? 0.42050 0.44760 0.43840 -0.01750 0.03550  -0.00960 2384 HOH A O   
6206 O  O   . HOH Q .   ? 0.57560 0.44830 0.47450 -0.06110 0.03970  0.02710  2385 HOH A O   
6207 O  O   . HOH Q .   ? 0.36720 0.33110 0.37200 -0.08030 0.04900  0.03170  2386 HOH A O   
6208 O  O   . HOH Q .   ? 0.53180 0.56630 0.58680 -0.03130 0.00690  0.08940  2387 HOH A O   
6209 O  O   . HOH Q .   ? 0.43180 0.43360 0.42400 0.00590  -0.01830 -0.02360 2388 HOH A O   
6210 O  O   . HOH Q .   ? 0.38080 0.38080 0.38090 0.00000  -0.00000 -0.00000 2389 HOH A O   
6211 O  O   . HOH Q .   ? 0.33640 0.27890 0.41970 0.07220  0.03840  0.06660  2390 HOH A O   
6212 O  O   . HOH Q .   ? 0.43540 0.40230 0.43580 -0.00000 0.00030  0.00000  2391 HOH A O   
6213 O  O   . HOH Q .   ? 0.66550 0.55450 0.48590 -0.05260 0.07510  -0.06650 2392 HOH A O   
6214 O  O   . HOH Q .   ? 0.40130 0.39380 0.39260 -0.00420 -0.00820 0.00520  2393 HOH A O   
6215 O  O   . HOH Q .   ? 0.33710 0.31360 0.41920 0.02320  -0.06760 0.01310  2394 HOH A O   
6216 O  O   . HOH Q .   ? 0.58000 0.46670 0.53340 0.14170  -0.07220 -0.01010 2395 HOH A O   
6217 O  O   . HOH Q .   ? 0.41300 0.39420 0.38950 0.02610  0.00270  0.00310  2396 HOH A O   
6218 O  O   . HOH Q .   ? 0.25020 0.34410 0.26520 -0.02670 0.03750  -0.00400 2397 HOH A O   
6219 O  O   . HOH Q .   ? 0.32950 0.38630 0.39860 0.04430  0.05590  -0.05870 2398 HOH A O   
6220 O  O   . HOH Q .   ? 0.38020 0.39560 0.39480 0.00080  -0.00820 0.00200  2399 HOH A O   
6221 O  O   . HOH Q .   ? 0.36510 0.50240 0.41420 -0.01140 -0.09140 -0.03460 2400 HOH A O   
6222 O  O   . HOH Q .   ? 0.34790 0.36170 0.42290 -0.12380 -0.03830 -0.05480 2401 HOH A O   
6223 O  O   . HOH Q .   ? 0.19020 0.22890 0.44880 0.02010  0.06480  -0.01630 2402 HOH A O   
6224 O  O   . HOH Q .   ? 0.39400 0.27580 0.33920 0.02760  -0.10220 -0.07920 2403 HOH A O   
6225 O  O   . HOH Q .   ? 0.42630 0.30550 0.35010 0.01590  0.01210  0.03170  2404 HOH A O   
6226 O  O   . HOH Q .   ? 0.57450 0.61220 0.47730 0.02770  -0.02370 0.01750  2405 HOH A O   
6227 O  O   . HOH Q .   ? 0.27830 0.55390 0.31160 -0.02690 -0.06950 -0.02450 2406 HOH A O   
6228 O  O   . HOH Q .   ? 0.31290 0.41870 0.39070 -0.01600 0.00610  -0.07740 2407 HOH A O   
6229 O  O   . HOH Q .   ? 0.42390 0.41420 0.43440 -0.04390 0.05700  -0.01700 2408 HOH A O   
6230 O  O   . HOH Q .   ? 0.56670 0.40780 0.53100 -0.10380 0.03940  0.01680  2409 HOH A O   
6231 O  O   . HOH Q .   ? 0.60420 0.50820 0.59760 -0.09510 -0.02850 -0.00510 2410 HOH A O   
6232 O  O   . HOH Q .   ? 0.60060 0.56240 0.55730 -0.00240 -0.04680 0.02340  2411 HOH A O   
6233 O  O   . HOH Q .   ? 0.48680 0.50930 0.39530 0.05110  0.01760  0.01480  2412 HOH A O   
6234 O  O   . HOH Q .   ? 0.41640 0.30460 0.27370 0.03560  -0.05100 -0.01470 2413 HOH A O   
6235 O  O   . HOH Q .   ? 0.39260 0.43270 0.44130 0.00820  -0.00370 -0.03790 2414 HOH A O   
6236 O  O   . HOH Q .   ? 0.42100 0.45910 0.34480 0.03720  0.10450  0.00500  2415 HOH A O   
6237 O  O   . HOH Q .   ? 0.36260 0.25470 0.43220 -0.03160 -0.03400 0.06650  2416 HOH A O   
6238 O  O   . HOH Q .   ? 0.44020 0.43630 0.41620 -0.05340 0.05240  -0.03430 2417 HOH A O   
6239 O  O   . HOH Q .   ? 0.38030 0.38010 0.31760 -0.02060 0.01640  -0.00470 2418 HOH A O   
6240 O  O   . HOH Q .   ? 0.32280 0.21020 0.33970 0.03570  0.10050  0.03980  2419 HOH A O   
6241 O  O   . HOH Q .   ? 0.43640 0.46760 0.53470 0.03950  0.04820  -0.09910 2420 HOH A O   
6242 O  O   . HOH Q .   ? 0.49400 0.53510 0.48440 -0.04900 0.03660  -0.11890 2421 HOH A O   
6243 O  O   . HOH Q .   ? 0.43170 0.33890 0.55970 -0.00290 0.00210  -0.00130 2422 HOH A O   
6244 O  O   . HOH Q .   ? 0.20650 0.30970 0.35740 0.02860  0.02940  0.02740  2423 HOH A O   
6245 O  O   . HOH Q .   ? 0.42960 0.40990 0.44190 -0.00300 -0.01630 0.02510  2424 HOH A O   
6246 O  O   . HOH Q .   ? 0.46650 0.37360 0.48830 -0.10590 0.11270  -0.07260 2425 HOH A O   
6247 O  O   . HOH Q .   ? 0.46100 0.39030 0.44320 -0.04660 0.06200  0.06370  2426 HOH A O   
6248 O  O   . HOH Q .   ? 0.30270 0.26330 0.28180 -0.08020 0.02990  -0.01230 2427 HOH A O   
6249 O  O   . HOH Q .   ? 0.41310 0.52760 0.42850 -0.01140 0.11600  0.07940  2428 HOH A O   
6250 O  O   . HOH Q .   ? 0.34220 0.35030 0.32050 -0.02030 0.06660  0.02690  2429 HOH A O   
6251 O  O   . HOH Q .   ? 0.40360 0.47090 0.44270 -0.00390 0.02070  -0.04950 2430 HOH A O   
6252 O  O   . HOH Q .   ? 0.39770 0.39080 0.39690 0.01350  0.00430  -0.01010 2431 HOH A O   
6253 O  O   . HOH Q .   ? 0.47490 0.40360 0.45740 -0.00000 0.00950  -0.00000 2432 HOH A O   
6254 O  O   . HOH Q .   ? 0.21540 0.26420 0.33700 0.04900  0.07690  0.00410  2433 HOH A O   
6255 O  O   . HOH Q .   ? 0.23140 0.37290 0.33950 -0.07260 0.00140  -0.05370 2434 HOH A O   
6256 O  O   . HOH Q .   ? 0.34450 0.49140 0.38750 0.06100  0.05030  0.08310  2435 HOH A O   
6257 O  O   . HOH Q .   ? 0.37750 0.44610 0.46190 -0.08460 0.03750  -0.01990 2436 HOH A O   
6258 O  O   . HOH Q .   ? 0.30730 0.27470 0.40870 0.04490  0.04800  -0.03550 2437 HOH A O   
6259 O  O   . HOH Q .   ? 0.37660 0.37770 0.47880 0.00970  -0.09710 -0.13160 2438 HOH A O   
6260 O  O   . HOH Q .   ? 0.30700 0.46180 0.36870 -0.08420 -0.06560 -0.07540 2439 HOH A O   
6261 O  O   . HOH Q .   ? 0.53350 0.46820 0.51690 -0.03600 0.08620  -0.00290 2440 HOH A O   
6262 O  O   . HOH Q .   ? 0.43490 0.43290 0.42750 -0.03290 0.00900  0.00260  2441 HOH A O   
# 
