data_9FM9
# 
_entry.id   9FM9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FM9         pdb_00009fm9 10.2210/pdb9fm9/pdb 
WWPDB D_1292139161 ?            ?                   
EMDB  EMD-50550    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-11 ? 
2 'EM metadata'     1 0 2025-06-11 ? 
3 'Half map'        1 0 2025-06-11 1 
4 'Half map'        1 0 2025-06-11 2 
5 Image             1 0 2025-06-11 ? 
6 'Primary map'     1 0 2025-06-11 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FM9 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Aldehyde dehydrogenase' 
_pdbx_database_related.db_id          EMD-50550 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 l.schada.von.borzyskowski@biology.leidenuniv.nl Lennart 'Schada von Borzyskowski' ? 'principal investigator/group leader' 
0000-0003-2952-4572 
3 m.r.ren@biology.leidenuniv.nl                   Minrui  Ren                       ? 'principal investigator/group leader' 
0009-0002-8673-9860 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lamers, M.H.'                1 0000-0002-4205-1338 
'Schada von Borzyskowski, L.' 2 0000-0003-2952-4572 
'Ren, M.'                     3 0009-0002-8673-9860 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Aldehyde dehydrogenase' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lamers, M.H.'                1 0000-0002-4205-1338 
primary 'Schada von Borzyskowski, L.' 2 0000-0003-2952-4572 
primary 'Ren, M.'                     3 0009-0002-8673-9860 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Aldehyde dehydrogenase' 58316.895 4 1.2.1.3 ? ? ? 
2 non-polymer syn 'POTASSIUM ION'          39.098    2 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Acetaldehyde dehydrogenase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGHHHHHHHHHHSSGHIEGRHMPNDQTHPFRGVNALPFEERYDNFIGGEWVAPVSGRYFTNTTPITGAEIGQIARSEAGD
IELALDAAHAAKEKWGATSPAERANIMLKIADRMERNLELLATAETWDNGKPIRETMAADLPLAIDHFRYFAGVLRAQEG
SISQIDDDTVAYHFHEPLGVVGQIIPWNFPLLMACWKLAPAIAAGNCVVLKPAEQTPAGIMVWANLIGDLLPPGVLNIVN
GFGLEAGKPLASSNRIAKIAFTGETTTGRLIMQYASENLIPVTLELGGKSPNIFFADVAREDDDFFDKALEGFTMFALNQ
GEVCTCPSRVLIQESIYDKFMERAVQRVQAIKQGDPRESDTMIGAQASSEQKEKILSYLDIGKKEGAEVLTGGKAADLGG
ELSGGYYIEPTIFRGNNKMRIFQEEIFGPVVSVTTFKDQAEALEIANDTLYGLGAGVWSRDANTCYRMGRGIKAGRVWTN
CYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQTKNMLVSYSPKKLGFF
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGHHHHHHHHHHSSGHIEGRHMPNDQTHPFRGVNALPFEERYDNFIGGEWVAPVSGRYFTNTTPITGAEIGQIARSEAGD
IELALDAAHAAKEKWGATSPAERANIMLKIADRMERNLELLATAETWDNGKPIRETMAADLPLAIDHFRYFAGVLRAQEG
SISQIDDDTVAYHFHEPLGVVGQIIPWNFPLLMACWKLAPAIAAGNCVVLKPAEQTPAGIMVWANLIGDLLPPGVLNIVN
GFGLEAGKPLASSNRIAKIAFTGETTTGRLIMQYASENLIPVTLELGGKSPNIFFADVAREDDDFFDKALEGFTMFALNQ
GEVCTCPSRVLIQESIYDKFMERAVQRVQAIKQGDPRESDTMIGAQASSEQKEKILSYLDIGKKEGAEVLTGGKAADLGG
ELSGGYYIEPTIFRGNNKMRIFQEEIFGPVVSVTTFKDQAEALEIANDTLYGLGAGVWSRDANTCYRMGRGIKAGRVWTN
CYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQTKNMLVSYSPKKLGFF
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'POTASSIUM ION' 
_pdbx_entity_nonpoly.comp_id     K 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  HIS n 
1 12  HIS n 
1 13  SER n 
1 14  SER n 
1 15  GLY n 
1 16  HIS n 
1 17  ILE n 
1 18  GLU n 
1 19  GLY n 
1 20  ARG n 
1 21  HIS n 
1 22  MET n 
1 23  PRO n 
1 24  ASN n 
1 25  ASP n 
1 26  GLN n 
1 27  THR n 
1 28  HIS n 
1 29  PRO n 
1 30  PHE n 
1 31  ARG n 
1 32  GLY n 
1 33  VAL n 
1 34  ASN n 
1 35  ALA n 
1 36  LEU n 
1 37  PRO n 
1 38  PHE n 
1 39  GLU n 
1 40  GLU n 
1 41  ARG n 
1 42  TYR n 
1 43  ASP n 
1 44  ASN n 
1 45  PHE n 
1 46  ILE n 
1 47  GLY n 
1 48  GLY n 
1 49  GLU n 
1 50  TRP n 
1 51  VAL n 
1 52  ALA n 
1 53  PRO n 
1 54  VAL n 
1 55  SER n 
1 56  GLY n 
1 57  ARG n 
1 58  TYR n 
1 59  PHE n 
1 60  THR n 
1 61  ASN n 
1 62  THR n 
1 63  THR n 
1 64  PRO n 
1 65  ILE n 
1 66  THR n 
1 67  GLY n 
1 68  ALA n 
1 69  GLU n 
1 70  ILE n 
1 71  GLY n 
1 72  GLN n 
1 73  ILE n 
1 74  ALA n 
1 75  ARG n 
1 76  SER n 
1 77  GLU n 
1 78  ALA n 
1 79  GLY n 
1 80  ASP n 
1 81  ILE n 
1 82  GLU n 
1 83  LEU n 
1 84  ALA n 
1 85  LEU n 
1 86  ASP n 
1 87  ALA n 
1 88  ALA n 
1 89  HIS n 
1 90  ALA n 
1 91  ALA n 
1 92  LYS n 
1 93  GLU n 
1 94  LYS n 
1 95  TRP n 
1 96  GLY n 
1 97  ALA n 
1 98  THR n 
1 99  SER n 
1 100 PRO n 
1 101 ALA n 
1 102 GLU n 
1 103 ARG n 
1 104 ALA n 
1 105 ASN n 
1 106 ILE n 
1 107 MET n 
1 108 LEU n 
1 109 LYS n 
1 110 ILE n 
1 111 ALA n 
1 112 ASP n 
1 113 ARG n 
1 114 MET n 
1 115 GLU n 
1 116 ARG n 
1 117 ASN n 
1 118 LEU n 
1 119 GLU n 
1 120 LEU n 
1 121 LEU n 
1 122 ALA n 
1 123 THR n 
1 124 ALA n 
1 125 GLU n 
1 126 THR n 
1 127 TRP n 
1 128 ASP n 
1 129 ASN n 
1 130 GLY n 
1 131 LYS n 
1 132 PRO n 
1 133 ILE n 
1 134 ARG n 
1 135 GLU n 
1 136 THR n 
1 137 MET n 
1 138 ALA n 
1 139 ALA n 
1 140 ASP n 
1 141 LEU n 
1 142 PRO n 
1 143 LEU n 
1 144 ALA n 
1 145 ILE n 
1 146 ASP n 
1 147 HIS n 
1 148 PHE n 
1 149 ARG n 
1 150 TYR n 
1 151 PHE n 
1 152 ALA n 
1 153 GLY n 
1 154 VAL n 
1 155 LEU n 
1 156 ARG n 
1 157 ALA n 
1 158 GLN n 
1 159 GLU n 
1 160 GLY n 
1 161 SER n 
1 162 ILE n 
1 163 SER n 
1 164 GLN n 
1 165 ILE n 
1 166 ASP n 
1 167 ASP n 
1 168 ASP n 
1 169 THR n 
1 170 VAL n 
1 171 ALA n 
1 172 TYR n 
1 173 HIS n 
1 174 PHE n 
1 175 HIS n 
1 176 GLU n 
1 177 PRO n 
1 178 LEU n 
1 179 GLY n 
1 180 VAL n 
1 181 VAL n 
1 182 GLY n 
1 183 GLN n 
1 184 ILE n 
1 185 ILE n 
1 186 PRO n 
1 187 TRP n 
1 188 ASN n 
1 189 PHE n 
1 190 PRO n 
1 191 LEU n 
1 192 LEU n 
1 193 MET n 
1 194 ALA n 
1 195 CYS n 
1 196 TRP n 
1 197 LYS n 
1 198 LEU n 
1 199 ALA n 
1 200 PRO n 
1 201 ALA n 
1 202 ILE n 
1 203 ALA n 
1 204 ALA n 
1 205 GLY n 
1 206 ASN n 
1 207 CYS n 
1 208 VAL n 
1 209 VAL n 
1 210 LEU n 
1 211 LYS n 
1 212 PRO n 
1 213 ALA n 
1 214 GLU n 
1 215 GLN n 
1 216 THR n 
1 217 PRO n 
1 218 ALA n 
1 219 GLY n 
1 220 ILE n 
1 221 MET n 
1 222 VAL n 
1 223 TRP n 
1 224 ALA n 
1 225 ASN n 
1 226 LEU n 
1 227 ILE n 
1 228 GLY n 
1 229 ASP n 
1 230 LEU n 
1 231 LEU n 
1 232 PRO n 
1 233 PRO n 
1 234 GLY n 
1 235 VAL n 
1 236 LEU n 
1 237 ASN n 
1 238 ILE n 
1 239 VAL n 
1 240 ASN n 
1 241 GLY n 
1 242 PHE n 
1 243 GLY n 
1 244 LEU n 
1 245 GLU n 
1 246 ALA n 
1 247 GLY n 
1 248 LYS n 
1 249 PRO n 
1 250 LEU n 
1 251 ALA n 
1 252 SER n 
1 253 SER n 
1 254 ASN n 
1 255 ARG n 
1 256 ILE n 
1 257 ALA n 
1 258 LYS n 
1 259 ILE n 
1 260 ALA n 
1 261 PHE n 
1 262 THR n 
1 263 GLY n 
1 264 GLU n 
1 265 THR n 
1 266 THR n 
1 267 THR n 
1 268 GLY n 
1 269 ARG n 
1 270 LEU n 
1 271 ILE n 
1 272 MET n 
1 273 GLN n 
1 274 TYR n 
1 275 ALA n 
1 276 SER n 
1 277 GLU n 
1 278 ASN n 
1 279 LEU n 
1 280 ILE n 
1 281 PRO n 
1 282 VAL n 
1 283 THR n 
1 284 LEU n 
1 285 GLU n 
1 286 LEU n 
1 287 GLY n 
1 288 GLY n 
1 289 LYS n 
1 290 SER n 
1 291 PRO n 
1 292 ASN n 
1 293 ILE n 
1 294 PHE n 
1 295 PHE n 
1 296 ALA n 
1 297 ASP n 
1 298 VAL n 
1 299 ALA n 
1 300 ARG n 
1 301 GLU n 
1 302 ASP n 
1 303 ASP n 
1 304 ASP n 
1 305 PHE n 
1 306 PHE n 
1 307 ASP n 
1 308 LYS n 
1 309 ALA n 
1 310 LEU n 
1 311 GLU n 
1 312 GLY n 
1 313 PHE n 
1 314 THR n 
1 315 MET n 
1 316 PHE n 
1 317 ALA n 
1 318 LEU n 
1 319 ASN n 
1 320 GLN n 
1 321 GLY n 
1 322 GLU n 
1 323 VAL n 
1 324 CYS n 
1 325 THR n 
1 326 CYS n 
1 327 PRO n 
1 328 SER n 
1 329 ARG n 
1 330 VAL n 
1 331 LEU n 
1 332 ILE n 
1 333 GLN n 
1 334 GLU n 
1 335 SER n 
1 336 ILE n 
1 337 TYR n 
1 338 ASP n 
1 339 LYS n 
1 340 PHE n 
1 341 MET n 
1 342 GLU n 
1 343 ARG n 
1 344 ALA n 
1 345 VAL n 
1 346 GLN n 
1 347 ARG n 
1 348 VAL n 
1 349 GLN n 
1 350 ALA n 
1 351 ILE n 
1 352 LYS n 
1 353 GLN n 
1 354 GLY n 
1 355 ASP n 
1 356 PRO n 
1 357 ARG n 
1 358 GLU n 
1 359 SER n 
1 360 ASP n 
1 361 THR n 
1 362 MET n 
1 363 ILE n 
1 364 GLY n 
1 365 ALA n 
1 366 GLN n 
1 367 ALA n 
1 368 SER n 
1 369 SER n 
1 370 GLU n 
1 371 GLN n 
1 372 LYS n 
1 373 GLU n 
1 374 LYS n 
1 375 ILE n 
1 376 LEU n 
1 377 SER n 
1 378 TYR n 
1 379 LEU n 
1 380 ASP n 
1 381 ILE n 
1 382 GLY n 
1 383 LYS n 
1 384 LYS n 
1 385 GLU n 
1 386 GLY n 
1 387 ALA n 
1 388 GLU n 
1 389 VAL n 
1 390 LEU n 
1 391 THR n 
1 392 GLY n 
1 393 GLY n 
1 394 LYS n 
1 395 ALA n 
1 396 ALA n 
1 397 ASP n 
1 398 LEU n 
1 399 GLY n 
1 400 GLY n 
1 401 GLU n 
1 402 LEU n 
1 403 SER n 
1 404 GLY n 
1 405 GLY n 
1 406 TYR n 
1 407 TYR n 
1 408 ILE n 
1 409 GLU n 
1 410 PRO n 
1 411 THR n 
1 412 ILE n 
1 413 PHE n 
1 414 ARG n 
1 415 GLY n 
1 416 ASN n 
1 417 ASN n 
1 418 LYS n 
1 419 MET n 
1 420 ARG n 
1 421 ILE n 
1 422 PHE n 
1 423 GLN n 
1 424 GLU n 
1 425 GLU n 
1 426 ILE n 
1 427 PHE n 
1 428 GLY n 
1 429 PRO n 
1 430 VAL n 
1 431 VAL n 
1 432 SER n 
1 433 VAL n 
1 434 THR n 
1 435 THR n 
1 436 PHE n 
1 437 LYS n 
1 438 ASP n 
1 439 GLN n 
1 440 ALA n 
1 441 GLU n 
1 442 ALA n 
1 443 LEU n 
1 444 GLU n 
1 445 ILE n 
1 446 ALA n 
1 447 ASN n 
1 448 ASP n 
1 449 THR n 
1 450 LEU n 
1 451 TYR n 
1 452 GLY n 
1 453 LEU n 
1 454 GLY n 
1 455 ALA n 
1 456 GLY n 
1 457 VAL n 
1 458 TRP n 
1 459 SER n 
1 460 ARG n 
1 461 ASP n 
1 462 ALA n 
1 463 ASN n 
1 464 THR n 
1 465 CYS n 
1 466 TYR n 
1 467 ARG n 
1 468 MET n 
1 469 GLY n 
1 470 ARG n 
1 471 GLY n 
1 472 ILE n 
1 473 LYS n 
1 474 ALA n 
1 475 GLY n 
1 476 ARG n 
1 477 VAL n 
1 478 TRP n 
1 479 THR n 
1 480 ASN n 
1 481 CYS n 
1 482 TYR n 
1 483 HIS n 
1 484 ALA n 
1 485 TYR n 
1 486 PRO n 
1 487 ALA n 
1 488 HIS n 
1 489 ALA n 
1 490 ALA n 
1 491 PHE n 
1 492 GLY n 
1 493 GLY n 
1 494 TYR n 
1 495 LYS n 
1 496 GLN n 
1 497 SER n 
1 498 GLY n 
1 499 ILE n 
1 500 GLY n 
1 501 ARG n 
1 502 GLU n 
1 503 THR n 
1 504 HIS n 
1 505 LYS n 
1 506 MET n 
1 507 MET n 
1 508 LEU n 
1 509 ASP n 
1 510 HIS n 
1 511 TYR n 
1 512 GLN n 
1 513 GLN n 
1 514 THR n 
1 515 LYS n 
1 516 ASN n 
1 517 MET n 
1 518 LEU n 
1 519 VAL n 
1 520 SER n 
1 521 TYR n 
1 522 SER n 
1 523 PRO n 
1 524 LYS n 
1 525 LYS n 
1 526 LEU n 
1 527 GLY n 
1 528 PHE n 
1 529 PHE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   529 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'adh, Pden_2366' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Paracoccus denitrificans' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     266 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
K   non-polymer         . 'POTASSIUM ION' ? 'K 1'            39.098  
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -20 ?   ?   ?   A . n 
A 1 2   GLY 2   -19 ?   ?   ?   A . n 
A 1 3   HIS 3   -18 ?   ?   ?   A . n 
A 1 4   HIS 4   -17 ?   ?   ?   A . n 
A 1 5   HIS 5   -16 ?   ?   ?   A . n 
A 1 6   HIS 6   -15 ?   ?   ?   A . n 
A 1 7   HIS 7   -14 ?   ?   ?   A . n 
A 1 8   HIS 8   -13 ?   ?   ?   A . n 
A 1 9   HIS 9   -12 ?   ?   ?   A . n 
A 1 10  HIS 10  -11 ?   ?   ?   A . n 
A 1 11  HIS 11  -10 ?   ?   ?   A . n 
A 1 12  HIS 12  -9  ?   ?   ?   A . n 
A 1 13  SER 13  -8  ?   ?   ?   A . n 
A 1 14  SER 14  -7  ?   ?   ?   A . n 
A 1 15  GLY 15  -6  ?   ?   ?   A . n 
A 1 16  HIS 16  -5  ?   ?   ?   A . n 
A 1 17  ILE 17  -4  ?   ?   ?   A . n 
A 1 18  GLU 18  -3  ?   ?   ?   A . n 
A 1 19  GLY 19  -2  ?   ?   ?   A . n 
A 1 20  ARG 20  -1  ?   ?   ?   A . n 
A 1 21  HIS 21  0   ?   ?   ?   A . n 
A 1 22  MET 22  1   ?   ?   ?   A . n 
A 1 23  PRO 23  2   ?   ?   ?   A . n 
A 1 24  ASN 24  3   ?   ?   ?   A . n 
A 1 25  ASP 25  4   ?   ?   ?   A . n 
A 1 26  GLN 26  5   ?   ?   ?   A . n 
A 1 27  THR 27  6   ?   ?   ?   A . n 
A 1 28  HIS 28  7   ?   ?   ?   A . n 
A 1 29  PRO 29  8   ?   ?   ?   A . n 
A 1 30  PHE 30  9   ?   ?   ?   A . n 
A 1 31  ARG 31  10  10  ARG ARG A . n 
A 1 32  GLY 32  11  11  GLY GLY A . n 
A 1 33  VAL 33  12  12  VAL VAL A . n 
A 1 34  ASN 34  13  13  ASN ASN A . n 
A 1 35  ALA 35  14  14  ALA ALA A . n 
A 1 36  LEU 36  15  15  LEU LEU A . n 
A 1 37  PRO 37  16  16  PRO PRO A . n 
A 1 38  PHE 38  17  17  PHE PHE A . n 
A 1 39  GLU 39  18  18  GLU GLU A . n 
A 1 40  GLU 40  19  19  GLU GLU A . n 
A 1 41  ARG 41  20  20  ARG ARG A . n 
A 1 42  TYR 42  21  21  TYR TYR A . n 
A 1 43  ASP 43  22  22  ASP ASP A . n 
A 1 44  ASN 44  23  23  ASN ASN A . n 
A 1 45  PHE 45  24  24  PHE PHE A . n 
A 1 46  ILE 46  25  25  ILE ILE A . n 
A 1 47  GLY 47  26  26  GLY GLY A . n 
A 1 48  GLY 48  27  27  GLY GLY A . n 
A 1 49  GLU 49  28  28  GLU GLU A . n 
A 1 50  TRP 50  29  29  TRP TRP A . n 
A 1 51  VAL 51  30  30  VAL VAL A . n 
A 1 52  ALA 52  31  31  ALA ALA A . n 
A 1 53  PRO 53  32  32  PRO PRO A . n 
A 1 54  VAL 54  33  33  VAL VAL A . n 
A 1 55  SER 55  34  34  SER SER A . n 
A 1 56  GLY 56  35  35  GLY GLY A . n 
A 1 57  ARG 57  36  36  ARG ARG A . n 
A 1 58  TYR 58  37  37  TYR TYR A . n 
A 1 59  PHE 59  38  38  PHE PHE A . n 
A 1 60  THR 60  39  39  THR THR A . n 
A 1 61  ASN 61  40  40  ASN ASN A . n 
A 1 62  THR 62  41  41  THR THR A . n 
A 1 63  THR 63  42  42  THR THR A . n 
A 1 64  PRO 64  43  43  PRO PRO A . n 
A 1 65  ILE 65  44  44  ILE ILE A . n 
A 1 66  THR 66  45  45  THR THR A . n 
A 1 67  GLY 67  46  46  GLY GLY A . n 
A 1 68  ALA 68  47  47  ALA ALA A . n 
A 1 69  GLU 69  48  48  GLU GLU A . n 
A 1 70  ILE 70  49  49  ILE ILE A . n 
A 1 71  GLY 71  50  50  GLY GLY A . n 
A 1 72  GLN 72  51  51  GLN GLN A . n 
A 1 73  ILE 73  52  52  ILE ILE A . n 
A 1 74  ALA 74  53  53  ALA ALA A . n 
A 1 75  ARG 75  54  54  ARG ARG A . n 
A 1 76  SER 76  55  55  SER SER A . n 
A 1 77  GLU 77  56  56  GLU GLU A . n 
A 1 78  ALA 78  57  57  ALA ALA A . n 
A 1 79  GLY 79  58  58  GLY GLY A . n 
A 1 80  ASP 80  59  59  ASP ASP A . n 
A 1 81  ILE 81  60  60  ILE ILE A . n 
A 1 82  GLU 82  61  61  GLU GLU A . n 
A 1 83  LEU 83  62  62  LEU LEU A . n 
A 1 84  ALA 84  63  63  ALA ALA A . n 
A 1 85  LEU 85  64  64  LEU LEU A . n 
A 1 86  ASP 86  65  65  ASP ASP A . n 
A 1 87  ALA 87  66  66  ALA ALA A . n 
A 1 88  ALA 88  67  67  ALA ALA A . n 
A 1 89  HIS 89  68  68  HIS HIS A . n 
A 1 90  ALA 90  69  69  ALA ALA A . n 
A 1 91  ALA 91  70  70  ALA ALA A . n 
A 1 92  LYS 92  71  71  LYS LYS A . n 
A 1 93  GLU 93  72  72  GLU GLU A . n 
A 1 94  LYS 94  73  73  LYS LYS A . n 
A 1 95  TRP 95  74  74  TRP TRP A . n 
A 1 96  GLY 96  75  75  GLY GLY A . n 
A 1 97  ALA 97  76  76  ALA ALA A . n 
A 1 98  THR 98  77  77  THR THR A . n 
A 1 99  SER 99  78  78  SER SER A . n 
A 1 100 PRO 100 79  79  PRO PRO A . n 
A 1 101 ALA 101 80  80  ALA ALA A . n 
A 1 102 GLU 102 81  81  GLU GLU A . n 
A 1 103 ARG 103 82  82  ARG ARG A . n 
A 1 104 ALA 104 83  83  ALA ALA A . n 
A 1 105 ASN 105 84  84  ASN ASN A . n 
A 1 106 ILE 106 85  85  ILE ILE A . n 
A 1 107 MET 107 86  86  MET MET A . n 
A 1 108 LEU 108 87  87  LEU LEU A . n 
A 1 109 LYS 109 88  88  LYS LYS A . n 
A 1 110 ILE 110 89  89  ILE ILE A . n 
A 1 111 ALA 111 90  90  ALA ALA A . n 
A 1 112 ASP 112 91  91  ASP ASP A . n 
A 1 113 ARG 113 92  92  ARG ARG A . n 
A 1 114 MET 114 93  93  MET MET A . n 
A 1 115 GLU 115 94  94  GLU GLU A . n 
A 1 116 ARG 116 95  95  ARG ARG A . n 
A 1 117 ASN 117 96  96  ASN ASN A . n 
A 1 118 LEU 118 97  97  LEU LEU A . n 
A 1 119 GLU 119 98  98  GLU GLU A . n 
A 1 120 LEU 120 99  99  LEU LEU A . n 
A 1 121 LEU 121 100 100 LEU LEU A . n 
A 1 122 ALA 122 101 101 ALA ALA A . n 
A 1 123 THR 123 102 102 THR THR A . n 
A 1 124 ALA 124 103 103 ALA ALA A . n 
A 1 125 GLU 125 104 104 GLU GLU A . n 
A 1 126 THR 126 105 105 THR THR A . n 
A 1 127 TRP 127 106 106 TRP TRP A . n 
A 1 128 ASP 128 107 107 ASP ASP A . n 
A 1 129 ASN 129 108 108 ASN ASN A . n 
A 1 130 GLY 130 109 109 GLY GLY A . n 
A 1 131 LYS 131 110 110 LYS LYS A . n 
A 1 132 PRO 132 111 111 PRO PRO A . n 
A 1 133 ILE 133 112 112 ILE ILE A . n 
A 1 134 ARG 134 113 113 ARG ARG A . n 
A 1 135 GLU 135 114 114 GLU GLU A . n 
A 1 136 THR 136 115 115 THR THR A . n 
A 1 137 MET 137 116 116 MET MET A . n 
A 1 138 ALA 138 117 117 ALA ALA A . n 
A 1 139 ALA 139 118 118 ALA ALA A . n 
A 1 140 ASP 140 119 119 ASP ASP A . n 
A 1 141 LEU 141 120 120 LEU LEU A . n 
A 1 142 PRO 142 121 121 PRO PRO A . n 
A 1 143 LEU 143 122 122 LEU LEU A . n 
A 1 144 ALA 144 123 123 ALA ALA A . n 
A 1 145 ILE 145 124 124 ILE ILE A . n 
A 1 146 ASP 146 125 125 ASP ASP A . n 
A 1 147 HIS 147 126 126 HIS HIS A . n 
A 1 148 PHE 148 127 127 PHE PHE A . n 
A 1 149 ARG 149 128 128 ARG ARG A . n 
A 1 150 TYR 150 129 129 TYR TYR A . n 
A 1 151 PHE 151 130 130 PHE PHE A . n 
A 1 152 ALA 152 131 131 ALA ALA A . n 
A 1 153 GLY 153 132 132 GLY GLY A . n 
A 1 154 VAL 154 133 133 VAL VAL A . n 
A 1 155 LEU 155 134 134 LEU LEU A . n 
A 1 156 ARG 156 135 135 ARG ARG A . n 
A 1 157 ALA 157 136 136 ALA ALA A . n 
A 1 158 GLN 158 137 137 GLN GLN A . n 
A 1 159 GLU 159 138 138 GLU GLU A . n 
A 1 160 GLY 160 139 139 GLY GLY A . n 
A 1 161 SER 161 140 140 SER SER A . n 
A 1 162 ILE 162 141 141 ILE ILE A . n 
A 1 163 SER 163 142 142 SER SER A . n 
A 1 164 GLN 164 143 143 GLN GLN A . n 
A 1 165 ILE 165 144 144 ILE ILE A . n 
A 1 166 ASP 166 145 145 ASP ASP A . n 
A 1 167 ASP 167 146 146 ASP ASP A . n 
A 1 168 ASP 168 147 147 ASP ASP A . n 
A 1 169 THR 169 148 148 THR THR A . n 
A 1 170 VAL 170 149 149 VAL VAL A . n 
A 1 171 ALA 171 150 150 ALA ALA A . n 
A 1 172 TYR 172 151 151 TYR TYR A . n 
A 1 173 HIS 173 152 152 HIS HIS A . n 
A 1 174 PHE 174 153 153 PHE PHE A . n 
A 1 175 HIS 175 154 154 HIS HIS A . n 
A 1 176 GLU 176 155 155 GLU GLU A . n 
A 1 177 PRO 177 156 156 PRO PRO A . n 
A 1 178 LEU 178 157 157 LEU LEU A . n 
A 1 179 GLY 179 158 158 GLY GLY A . n 
A 1 180 VAL 180 159 159 VAL VAL A . n 
A 1 181 VAL 181 160 160 VAL VAL A . n 
A 1 182 GLY 182 161 161 GLY GLY A . n 
A 1 183 GLN 183 162 162 GLN GLN A . n 
A 1 184 ILE 184 163 163 ILE ILE A . n 
A 1 185 ILE 185 164 164 ILE ILE A . n 
A 1 186 PRO 186 165 165 PRO PRO A . n 
A 1 187 TRP 187 166 166 TRP TRP A . n 
A 1 188 ASN 188 167 167 ASN ASN A . n 
A 1 189 PHE 189 168 168 PHE PHE A . n 
A 1 190 PRO 190 169 169 PRO PRO A . n 
A 1 191 LEU 191 170 170 LEU LEU A . n 
A 1 192 LEU 192 171 171 LEU LEU A . n 
A 1 193 MET 193 172 172 MET MET A . n 
A 1 194 ALA 194 173 173 ALA ALA A . n 
A 1 195 CYS 195 174 174 CYS CYS A . n 
A 1 196 TRP 196 175 175 TRP TRP A . n 
A 1 197 LYS 197 176 176 LYS LYS A . n 
A 1 198 LEU 198 177 177 LEU LEU A . n 
A 1 199 ALA 199 178 178 ALA ALA A . n 
A 1 200 PRO 200 179 179 PRO PRO A . n 
A 1 201 ALA 201 180 180 ALA ALA A . n 
A 1 202 ILE 202 181 181 ILE ILE A . n 
A 1 203 ALA 203 182 182 ALA ALA A . n 
A 1 204 ALA 204 183 183 ALA ALA A . n 
A 1 205 GLY 205 184 184 GLY GLY A . n 
A 1 206 ASN 206 185 185 ASN ASN A . n 
A 1 207 CYS 207 186 186 CYS CYS A . n 
A 1 208 VAL 208 187 187 VAL VAL A . n 
A 1 209 VAL 209 188 188 VAL VAL A . n 
A 1 210 LEU 210 189 189 LEU LEU A . n 
A 1 211 LYS 211 190 190 LYS LYS A . n 
A 1 212 PRO 212 191 191 PRO PRO A . n 
A 1 213 ALA 213 192 192 ALA ALA A . n 
A 1 214 GLU 214 193 193 GLU GLU A . n 
A 1 215 GLN 215 194 194 GLN GLN A . n 
A 1 216 THR 216 195 195 THR THR A . n 
A 1 217 PRO 217 196 196 PRO PRO A . n 
A 1 218 ALA 218 197 197 ALA ALA A . n 
A 1 219 GLY 219 198 198 GLY GLY A . n 
A 1 220 ILE 220 199 199 ILE ILE A . n 
A 1 221 MET 221 200 200 MET MET A . n 
A 1 222 VAL 222 201 201 VAL VAL A . n 
A 1 223 TRP 223 202 202 TRP TRP A . n 
A 1 224 ALA 224 203 203 ALA ALA A . n 
A 1 225 ASN 225 204 204 ASN ASN A . n 
A 1 226 LEU 226 205 205 LEU LEU A . n 
A 1 227 ILE 227 206 206 ILE ILE A . n 
A 1 228 GLY 228 207 207 GLY GLY A . n 
A 1 229 ASP 229 208 208 ASP ASP A . n 
A 1 230 LEU 230 209 209 LEU LEU A . n 
A 1 231 LEU 231 210 210 LEU LEU A . n 
A 1 232 PRO 232 211 211 PRO PRO A . n 
A 1 233 PRO 233 212 212 PRO PRO A . n 
A 1 234 GLY 234 213 213 GLY GLY A . n 
A 1 235 VAL 235 214 214 VAL VAL A . n 
A 1 236 LEU 236 215 215 LEU LEU A . n 
A 1 237 ASN 237 216 216 ASN ASN A . n 
A 1 238 ILE 238 217 217 ILE ILE A . n 
A 1 239 VAL 239 218 218 VAL VAL A . n 
A 1 240 ASN 240 219 219 ASN ASN A . n 
A 1 241 GLY 241 220 220 GLY GLY A . n 
A 1 242 PHE 242 221 221 PHE PHE A . n 
A 1 243 GLY 243 222 222 GLY GLY A . n 
A 1 244 LEU 244 223 223 LEU LEU A . n 
A 1 245 GLU 245 224 224 GLU GLU A . n 
A 1 246 ALA 246 225 225 ALA ALA A . n 
A 1 247 GLY 247 226 226 GLY GLY A . n 
A 1 248 LYS 248 227 227 LYS LYS A . n 
A 1 249 PRO 249 228 228 PRO PRO A . n 
A 1 250 LEU 250 229 229 LEU LEU A . n 
A 1 251 ALA 251 230 230 ALA ALA A . n 
A 1 252 SER 252 231 231 SER SER A . n 
A 1 253 SER 253 232 232 SER SER A . n 
A 1 254 ASN 254 233 233 ASN ASN A . n 
A 1 255 ARG 255 234 234 ARG ARG A . n 
A 1 256 ILE 256 235 235 ILE ILE A . n 
A 1 257 ALA 257 236 236 ALA ALA A . n 
A 1 258 LYS 258 237 237 LYS LYS A . n 
A 1 259 ILE 259 238 238 ILE ILE A . n 
A 1 260 ALA 260 239 239 ALA ALA A . n 
A 1 261 PHE 261 240 240 PHE PHE A . n 
A 1 262 THR 262 241 241 THR THR A . n 
A 1 263 GLY 263 242 242 GLY GLY A . n 
A 1 264 GLU 264 243 243 GLU GLU A . n 
A 1 265 THR 265 244 244 THR THR A . n 
A 1 266 THR 266 245 245 THR THR A . n 
A 1 267 THR 267 246 246 THR THR A . n 
A 1 268 GLY 268 247 247 GLY GLY A . n 
A 1 269 ARG 269 248 248 ARG ARG A . n 
A 1 270 LEU 270 249 249 LEU LEU A . n 
A 1 271 ILE 271 250 250 ILE ILE A . n 
A 1 272 MET 272 251 251 MET MET A . n 
A 1 273 GLN 273 252 252 GLN GLN A . n 
A 1 274 TYR 274 253 253 TYR TYR A . n 
A 1 275 ALA 275 254 254 ALA ALA A . n 
A 1 276 SER 276 255 255 SER SER A . n 
A 1 277 GLU 277 256 256 GLU GLU A . n 
A 1 278 ASN 278 257 257 ASN ASN A . n 
A 1 279 LEU 279 258 258 LEU LEU A . n 
A 1 280 ILE 280 259 259 ILE ILE A . n 
A 1 281 PRO 281 260 260 PRO PRO A . n 
A 1 282 VAL 282 261 261 VAL VAL A . n 
A 1 283 THR 283 262 262 THR THR A . n 
A 1 284 LEU 284 263 263 LEU LEU A . n 
A 1 285 GLU 285 264 264 GLU GLU A . n 
A 1 286 LEU 286 265 265 LEU LEU A . n 
A 1 287 GLY 287 266 266 GLY GLY A . n 
A 1 288 GLY 288 267 267 GLY GLY A . n 
A 1 289 LYS 289 268 268 LYS LYS A . n 
A 1 290 SER 290 269 269 SER SER A . n 
A 1 291 PRO 291 270 270 PRO PRO A . n 
A 1 292 ASN 292 271 271 ASN ASN A . n 
A 1 293 ILE 293 272 272 ILE ILE A . n 
A 1 294 PHE 294 273 273 PHE PHE A . n 
A 1 295 PHE 295 274 274 PHE PHE A . n 
A 1 296 ALA 296 275 275 ALA ALA A . n 
A 1 297 ASP 297 276 276 ASP ASP A . n 
A 1 298 VAL 298 277 277 VAL VAL A . n 
A 1 299 ALA 299 278 278 ALA ALA A . n 
A 1 300 ARG 300 279 279 ARG ARG A . n 
A 1 301 GLU 301 280 280 GLU GLU A . n 
A 1 302 ASP 302 281 281 ASP ASP A . n 
A 1 303 ASP 303 282 282 ASP ASP A . n 
A 1 304 ASP 304 283 283 ASP ASP A . n 
A 1 305 PHE 305 284 284 PHE PHE A . n 
A 1 306 PHE 306 285 285 PHE PHE A . n 
A 1 307 ASP 307 286 286 ASP ASP A . n 
A 1 308 LYS 308 287 287 LYS LYS A . n 
A 1 309 ALA 309 288 288 ALA ALA A . n 
A 1 310 LEU 310 289 289 LEU LEU A . n 
A 1 311 GLU 311 290 290 GLU GLU A . n 
A 1 312 GLY 312 291 291 GLY GLY A . n 
A 1 313 PHE 313 292 292 PHE PHE A . n 
A 1 314 THR 314 293 293 THR THR A . n 
A 1 315 MET 315 294 294 MET MET A . n 
A 1 316 PHE 316 295 295 PHE PHE A . n 
A 1 317 ALA 317 296 296 ALA ALA A . n 
A 1 318 LEU 318 297 297 LEU LEU A . n 
A 1 319 ASN 319 298 298 ASN ASN A . n 
A 1 320 GLN 320 299 299 GLN GLN A . n 
A 1 321 GLY 321 300 300 GLY GLY A . n 
A 1 322 GLU 322 301 301 GLU GLU A . n 
A 1 323 VAL 323 302 302 VAL VAL A . n 
A 1 324 CYS 324 303 303 CYS CYS A . n 
A 1 325 THR 325 304 304 THR THR A . n 
A 1 326 CYS 326 305 305 CYS CYS A . n 
A 1 327 PRO 327 306 306 PRO PRO A . n 
A 1 328 SER 328 307 307 SER SER A . n 
A 1 329 ARG 329 308 308 ARG ARG A . n 
A 1 330 VAL 330 309 309 VAL VAL A . n 
A 1 331 LEU 331 310 310 LEU LEU A . n 
A 1 332 ILE 332 311 311 ILE ILE A . n 
A 1 333 GLN 333 312 312 GLN GLN A . n 
A 1 334 GLU 334 313 313 GLU GLU A . n 
A 1 335 SER 335 314 314 SER SER A . n 
A 1 336 ILE 336 315 315 ILE ILE A . n 
A 1 337 TYR 337 316 316 TYR TYR A . n 
A 1 338 ASP 338 317 317 ASP ASP A . n 
A 1 339 LYS 339 318 318 LYS LYS A . n 
A 1 340 PHE 340 319 319 PHE PHE A . n 
A 1 341 MET 341 320 320 MET MET A . n 
A 1 342 GLU 342 321 321 GLU GLU A . n 
A 1 343 ARG 343 322 322 ARG ARG A . n 
A 1 344 ALA 344 323 323 ALA ALA A . n 
A 1 345 VAL 345 324 324 VAL VAL A . n 
A 1 346 GLN 346 325 325 GLN GLN A . n 
A 1 347 ARG 347 326 326 ARG ARG A . n 
A 1 348 VAL 348 327 327 VAL VAL A . n 
A 1 349 GLN 349 328 328 GLN GLN A . n 
A 1 350 ALA 350 329 329 ALA ALA A . n 
A 1 351 ILE 351 330 330 ILE ILE A . n 
A 1 352 LYS 352 331 331 LYS LYS A . n 
A 1 353 GLN 353 332 332 GLN GLN A . n 
A 1 354 GLY 354 333 333 GLY GLY A . n 
A 1 355 ASP 355 334 334 ASP ASP A . n 
A 1 356 PRO 356 335 335 PRO PRO A . n 
A 1 357 ARG 357 336 336 ARG ARG A . n 
A 1 358 GLU 358 337 337 GLU GLU A . n 
A 1 359 SER 359 338 338 SER SER A . n 
A 1 360 ASP 360 339 339 ASP ASP A . n 
A 1 361 THR 361 340 340 THR THR A . n 
A 1 362 MET 362 341 341 MET MET A . n 
A 1 363 ILE 363 342 342 ILE ILE A . n 
A 1 364 GLY 364 343 343 GLY GLY A . n 
A 1 365 ALA 365 344 344 ALA ALA A . n 
A 1 366 GLN 366 345 345 GLN GLN A . n 
A 1 367 ALA 367 346 346 ALA ALA A . n 
A 1 368 SER 368 347 347 SER SER A . n 
A 1 369 SER 369 348 348 SER SER A . n 
A 1 370 GLU 370 349 349 GLU GLU A . n 
A 1 371 GLN 371 350 350 GLN GLN A . n 
A 1 372 LYS 372 351 351 LYS LYS A . n 
A 1 373 GLU 373 352 352 GLU GLU A . n 
A 1 374 LYS 374 353 353 LYS LYS A . n 
A 1 375 ILE 375 354 354 ILE ILE A . n 
A 1 376 LEU 376 355 355 LEU LEU A . n 
A 1 377 SER 377 356 356 SER SER A . n 
A 1 378 TYR 378 357 357 TYR TYR A . n 
A 1 379 LEU 379 358 358 LEU LEU A . n 
A 1 380 ASP 380 359 359 ASP ASP A . n 
A 1 381 ILE 381 360 360 ILE ILE A . n 
A 1 382 GLY 382 361 361 GLY GLY A . n 
A 1 383 LYS 383 362 362 LYS LYS A . n 
A 1 384 LYS 384 363 363 LYS LYS A . n 
A 1 385 GLU 385 364 364 GLU GLU A . n 
A 1 386 GLY 386 365 365 GLY GLY A . n 
A 1 387 ALA 387 366 366 ALA ALA A . n 
A 1 388 GLU 388 367 367 GLU GLU A . n 
A 1 389 VAL 389 368 368 VAL VAL A . n 
A 1 390 LEU 390 369 369 LEU LEU A . n 
A 1 391 THR 391 370 370 THR THR A . n 
A 1 392 GLY 392 371 371 GLY GLY A . n 
A 1 393 GLY 393 372 372 GLY GLY A . n 
A 1 394 LYS 394 373 373 LYS LYS A . n 
A 1 395 ALA 395 374 374 ALA ALA A . n 
A 1 396 ALA 396 375 375 ALA ALA A . n 
A 1 397 ASP 397 376 376 ASP ASP A . n 
A 1 398 LEU 398 377 377 LEU LEU A . n 
A 1 399 GLY 399 378 378 GLY GLY A . n 
A 1 400 GLY 400 379 379 GLY GLY A . n 
A 1 401 GLU 401 380 380 GLU GLU A . n 
A 1 402 LEU 402 381 381 LEU LEU A . n 
A 1 403 SER 403 382 382 SER SER A . n 
A 1 404 GLY 404 383 383 GLY GLY A . n 
A 1 405 GLY 405 384 384 GLY GLY A . n 
A 1 406 TYR 406 385 385 TYR TYR A . n 
A 1 407 TYR 407 386 386 TYR TYR A . n 
A 1 408 ILE 408 387 387 ILE ILE A . n 
A 1 409 GLU 409 388 388 GLU GLU A . n 
A 1 410 PRO 410 389 389 PRO PRO A . n 
A 1 411 THR 411 390 390 THR THR A . n 
A 1 412 ILE 412 391 391 ILE ILE A . n 
A 1 413 PHE 413 392 392 PHE PHE A . n 
A 1 414 ARG 414 393 393 ARG ARG A . n 
A 1 415 GLY 415 394 394 GLY GLY A . n 
A 1 416 ASN 416 395 395 ASN ASN A . n 
A 1 417 ASN 417 396 396 ASN ASN A . n 
A 1 418 LYS 418 397 397 LYS LYS A . n 
A 1 419 MET 419 398 398 MET MET A . n 
A 1 420 ARG 420 399 399 ARG ARG A . n 
A 1 421 ILE 421 400 400 ILE ILE A . n 
A 1 422 PHE 422 401 401 PHE PHE A . n 
A 1 423 GLN 423 402 402 GLN GLN A . n 
A 1 424 GLU 424 403 403 GLU GLU A . n 
A 1 425 GLU 425 404 404 GLU GLU A . n 
A 1 426 ILE 426 405 405 ILE ILE A . n 
A 1 427 PHE 427 406 406 PHE PHE A . n 
A 1 428 GLY 428 407 407 GLY GLY A . n 
A 1 429 PRO 429 408 408 PRO PRO A . n 
A 1 430 VAL 430 409 409 VAL VAL A . n 
A 1 431 VAL 431 410 410 VAL VAL A . n 
A 1 432 SER 432 411 411 SER SER A . n 
A 1 433 VAL 433 412 412 VAL VAL A . n 
A 1 434 THR 434 413 413 THR THR A . n 
A 1 435 THR 435 414 414 THR THR A . n 
A 1 436 PHE 436 415 415 PHE PHE A . n 
A 1 437 LYS 437 416 416 LYS LYS A . n 
A 1 438 ASP 438 417 417 ASP ASP A . n 
A 1 439 GLN 439 418 418 GLN GLN A . n 
A 1 440 ALA 440 419 419 ALA ALA A . n 
A 1 441 GLU 441 420 420 GLU GLU A . n 
A 1 442 ALA 442 421 421 ALA ALA A . n 
A 1 443 LEU 443 422 422 LEU LEU A . n 
A 1 444 GLU 444 423 423 GLU GLU A . n 
A 1 445 ILE 445 424 424 ILE ILE A . n 
A 1 446 ALA 446 425 425 ALA ALA A . n 
A 1 447 ASN 447 426 426 ASN ASN A . n 
A 1 448 ASP 448 427 427 ASP ASP A . n 
A 1 449 THR 449 428 428 THR THR A . n 
A 1 450 LEU 450 429 429 LEU LEU A . n 
A 1 451 TYR 451 430 430 TYR TYR A . n 
A 1 452 GLY 452 431 431 GLY GLY A . n 
A 1 453 LEU 453 432 432 LEU LEU A . n 
A 1 454 GLY 454 433 433 GLY GLY A . n 
A 1 455 ALA 455 434 434 ALA ALA A . n 
A 1 456 GLY 456 435 435 GLY GLY A . n 
A 1 457 VAL 457 436 436 VAL VAL A . n 
A 1 458 TRP 458 437 437 TRP TRP A . n 
A 1 459 SER 459 438 438 SER SER A . n 
A 1 460 ARG 460 439 439 ARG ARG A . n 
A 1 461 ASP 461 440 440 ASP ASP A . n 
A 1 462 ALA 462 441 441 ALA ALA A . n 
A 1 463 ASN 463 442 442 ASN ASN A . n 
A 1 464 THR 464 443 443 THR THR A . n 
A 1 465 CYS 465 444 444 CYS CYS A . n 
A 1 466 TYR 466 445 445 TYR TYR A . n 
A 1 467 ARG 467 446 446 ARG ARG A . n 
A 1 468 MET 468 447 447 MET MET A . n 
A 1 469 GLY 469 448 448 GLY GLY A . n 
A 1 470 ARG 470 449 449 ARG ARG A . n 
A 1 471 GLY 471 450 450 GLY GLY A . n 
A 1 472 ILE 472 451 451 ILE ILE A . n 
A 1 473 LYS 473 452 452 LYS LYS A . n 
A 1 474 ALA 474 453 453 ALA ALA A . n 
A 1 475 GLY 475 454 454 GLY GLY A . n 
A 1 476 ARG 476 455 455 ARG ARG A . n 
A 1 477 VAL 477 456 456 VAL VAL A . n 
A 1 478 TRP 478 457 457 TRP TRP A . n 
A 1 479 THR 479 458 458 THR THR A . n 
A 1 480 ASN 480 459 459 ASN ASN A . n 
A 1 481 CYS 481 460 460 CYS CYS A . n 
A 1 482 TYR 482 461 461 TYR TYR A . n 
A 1 483 HIS 483 462 462 HIS HIS A . n 
A 1 484 ALA 484 463 463 ALA ALA A . n 
A 1 485 TYR 485 464 464 TYR TYR A . n 
A 1 486 PRO 486 465 465 PRO PRO A . n 
A 1 487 ALA 487 466 466 ALA ALA A . n 
A 1 488 HIS 488 467 467 HIS HIS A . n 
A 1 489 ALA 489 468 468 ALA ALA A . n 
A 1 490 ALA 490 469 469 ALA ALA A . n 
A 1 491 PHE 491 470 470 PHE PHE A . n 
A 1 492 GLY 492 471 471 GLY GLY A . n 
A 1 493 GLY 493 472 472 GLY GLY A . n 
A 1 494 TYR 494 473 473 TYR TYR A . n 
A 1 495 LYS 495 474 474 LYS LYS A . n 
A 1 496 GLN 496 475 475 GLN GLN A . n 
A 1 497 SER 497 476 476 SER SER A . n 
A 1 498 GLY 498 477 477 GLY GLY A . n 
A 1 499 ILE 499 478 478 ILE ILE A . n 
A 1 500 GLY 500 479 479 GLY GLY A . n 
A 1 501 ARG 501 480 480 ARG ARG A . n 
A 1 502 GLU 502 481 481 GLU GLU A . n 
A 1 503 THR 503 482 482 THR THR A . n 
A 1 504 HIS 504 483 483 HIS HIS A . n 
A 1 505 LYS 505 484 484 LYS LYS A . n 
A 1 506 MET 506 485 485 MET MET A . n 
A 1 507 MET 507 486 486 MET MET A . n 
A 1 508 LEU 508 487 487 LEU LEU A . n 
A 1 509 ASP 509 488 488 ASP ASP A . n 
A 1 510 HIS 510 489 489 HIS HIS A . n 
A 1 511 TYR 511 490 490 TYR TYR A . n 
A 1 512 GLN 512 491 491 GLN GLN A . n 
A 1 513 GLN 513 492 492 GLN GLN A . n 
A 1 514 THR 514 493 493 THR THR A . n 
A 1 515 LYS 515 494 494 LYS LYS A . n 
A 1 516 ASN 516 495 495 ASN ASN A . n 
A 1 517 MET 517 496 496 MET MET A . n 
A 1 518 LEU 518 497 497 LEU LEU A . n 
A 1 519 VAL 519 498 498 VAL VAL A . n 
A 1 520 SER 520 499 499 SER SER A . n 
A 1 521 TYR 521 500 500 TYR TYR A . n 
A 1 522 SER 522 501 501 SER SER A . n 
A 1 523 PRO 523 502 502 PRO PRO A . n 
A 1 524 LYS 524 503 503 LYS LYS A . n 
A 1 525 LYS 525 504 504 LYS LYS A . n 
A 1 526 LEU 526 505 505 LEU LEU A . n 
A 1 527 GLY 527 506 506 GLY GLY A . n 
A 1 528 PHE 528 507 507 PHE PHE A . n 
A 1 529 PHE 529 508 508 PHE PHE A . n 
B 1 1   MET 1   -20 ?   ?   ?   B . n 
B 1 2   GLY 2   -19 ?   ?   ?   B . n 
B 1 3   HIS 3   -18 ?   ?   ?   B . n 
B 1 4   HIS 4   -17 ?   ?   ?   B . n 
B 1 5   HIS 5   -16 ?   ?   ?   B . n 
B 1 6   HIS 6   -15 ?   ?   ?   B . n 
B 1 7   HIS 7   -14 ?   ?   ?   B . n 
B 1 8   HIS 8   -13 ?   ?   ?   B . n 
B 1 9   HIS 9   -12 ?   ?   ?   B . n 
B 1 10  HIS 10  -11 ?   ?   ?   B . n 
B 1 11  HIS 11  -10 ?   ?   ?   B . n 
B 1 12  HIS 12  -9  ?   ?   ?   B . n 
B 1 13  SER 13  -8  ?   ?   ?   B . n 
B 1 14  SER 14  -7  ?   ?   ?   B . n 
B 1 15  GLY 15  -6  ?   ?   ?   B . n 
B 1 16  HIS 16  -5  ?   ?   ?   B . n 
B 1 17  ILE 17  -4  ?   ?   ?   B . n 
B 1 18  GLU 18  -3  ?   ?   ?   B . n 
B 1 19  GLY 19  -2  ?   ?   ?   B . n 
B 1 20  ARG 20  -1  ?   ?   ?   B . n 
B 1 21  HIS 21  0   ?   ?   ?   B . n 
B 1 22  MET 22  1   ?   ?   ?   B . n 
B 1 23  PRO 23  2   ?   ?   ?   B . n 
B 1 24  ASN 24  3   ?   ?   ?   B . n 
B 1 25  ASP 25  4   ?   ?   ?   B . n 
B 1 26  GLN 26  5   ?   ?   ?   B . n 
B 1 27  THR 27  6   ?   ?   ?   B . n 
B 1 28  HIS 28  7   ?   ?   ?   B . n 
B 1 29  PRO 29  8   ?   ?   ?   B . n 
B 1 30  PHE 30  9   ?   ?   ?   B . n 
B 1 31  ARG 31  10  ?   ?   ?   B . n 
B 1 32  GLY 32  11  11  GLY GLY B . n 
B 1 33  VAL 33  12  12  VAL VAL B . n 
B 1 34  ASN 34  13  13  ASN ASN B . n 
B 1 35  ALA 35  14  14  ALA ALA B . n 
B 1 36  LEU 36  15  15  LEU LEU B . n 
B 1 37  PRO 37  16  16  PRO PRO B . n 
B 1 38  PHE 38  17  17  PHE PHE B . n 
B 1 39  GLU 39  18  18  GLU GLU B . n 
B 1 40  GLU 40  19  19  GLU GLU B . n 
B 1 41  ARG 41  20  20  ARG ARG B . n 
B 1 42  TYR 42  21  21  TYR TYR B . n 
B 1 43  ASP 43  22  22  ASP ASP B . n 
B 1 44  ASN 44  23  23  ASN ASN B . n 
B 1 45  PHE 45  24  24  PHE PHE B . n 
B 1 46  ILE 46  25  25  ILE ILE B . n 
B 1 47  GLY 47  26  26  GLY GLY B . n 
B 1 48  GLY 48  27  27  GLY GLY B . n 
B 1 49  GLU 49  28  28  GLU GLU B . n 
B 1 50  TRP 50  29  29  TRP TRP B . n 
B 1 51  VAL 51  30  30  VAL VAL B . n 
B 1 52  ALA 52  31  31  ALA ALA B . n 
B 1 53  PRO 53  32  32  PRO PRO B . n 
B 1 54  VAL 54  33  33  VAL VAL B . n 
B 1 55  SER 55  34  34  SER SER B . n 
B 1 56  GLY 56  35  35  GLY GLY B . n 
B 1 57  ARG 57  36  36  ARG ARG B . n 
B 1 58  TYR 58  37  37  TYR TYR B . n 
B 1 59  PHE 59  38  38  PHE PHE B . n 
B 1 60  THR 60  39  39  THR THR B . n 
B 1 61  ASN 61  40  40  ASN ASN B . n 
B 1 62  THR 62  41  41  THR THR B . n 
B 1 63  THR 63  42  42  THR THR B . n 
B 1 64  PRO 64  43  43  PRO PRO B . n 
B 1 65  ILE 65  44  44  ILE ILE B . n 
B 1 66  THR 66  45  45  THR THR B . n 
B 1 67  GLY 67  46  46  GLY GLY B . n 
B 1 68  ALA 68  47  47  ALA ALA B . n 
B 1 69  GLU 69  48  48  GLU GLU B . n 
B 1 70  ILE 70  49  49  ILE ILE B . n 
B 1 71  GLY 71  50  50  GLY GLY B . n 
B 1 72  GLN 72  51  51  GLN GLN B . n 
B 1 73  ILE 73  52  52  ILE ILE B . n 
B 1 74  ALA 74  53  53  ALA ALA B . n 
B 1 75  ARG 75  54  54  ARG ARG B . n 
B 1 76  SER 76  55  55  SER SER B . n 
B 1 77  GLU 77  56  56  GLU GLU B . n 
B 1 78  ALA 78  57  57  ALA ALA B . n 
B 1 79  GLY 79  58  58  GLY GLY B . n 
B 1 80  ASP 80  59  59  ASP ASP B . n 
B 1 81  ILE 81  60  60  ILE ILE B . n 
B 1 82  GLU 82  61  61  GLU GLU B . n 
B 1 83  LEU 83  62  62  LEU LEU B . n 
B 1 84  ALA 84  63  63  ALA ALA B . n 
B 1 85  LEU 85  64  64  LEU LEU B . n 
B 1 86  ASP 86  65  65  ASP ASP B . n 
B 1 87  ALA 87  66  66  ALA ALA B . n 
B 1 88  ALA 88  67  67  ALA ALA B . n 
B 1 89  HIS 89  68  68  HIS HIS B . n 
B 1 90  ALA 90  69  69  ALA ALA B . n 
B 1 91  ALA 91  70  70  ALA ALA B . n 
B 1 92  LYS 92  71  71  LYS LYS B . n 
B 1 93  GLU 93  72  72  GLU GLU B . n 
B 1 94  LYS 94  73  73  LYS LYS B . n 
B 1 95  TRP 95  74  74  TRP TRP B . n 
B 1 96  GLY 96  75  75  GLY GLY B . n 
B 1 97  ALA 97  76  76  ALA ALA B . n 
B 1 98  THR 98  77  77  THR THR B . n 
B 1 99  SER 99  78  78  SER SER B . n 
B 1 100 PRO 100 79  79  PRO PRO B . n 
B 1 101 ALA 101 80  80  ALA ALA B . n 
B 1 102 GLU 102 81  81  GLU GLU B . n 
B 1 103 ARG 103 82  82  ARG ARG B . n 
B 1 104 ALA 104 83  83  ALA ALA B . n 
B 1 105 ASN 105 84  84  ASN ASN B . n 
B 1 106 ILE 106 85  85  ILE ILE B . n 
B 1 107 MET 107 86  86  MET MET B . n 
B 1 108 LEU 108 87  87  LEU LEU B . n 
B 1 109 LYS 109 88  88  LYS LYS B . n 
B 1 110 ILE 110 89  89  ILE ILE B . n 
B 1 111 ALA 111 90  90  ALA ALA B . n 
B 1 112 ASP 112 91  91  ASP ASP B . n 
B 1 113 ARG 113 92  92  ARG ARG B . n 
B 1 114 MET 114 93  93  MET MET B . n 
B 1 115 GLU 115 94  94  GLU GLU B . n 
B 1 116 ARG 116 95  95  ARG ARG B . n 
B 1 117 ASN 117 96  96  ASN ASN B . n 
B 1 118 LEU 118 97  97  LEU LEU B . n 
B 1 119 GLU 119 98  98  GLU GLU B . n 
B 1 120 LEU 120 99  99  LEU LEU B . n 
B 1 121 LEU 121 100 100 LEU LEU B . n 
B 1 122 ALA 122 101 101 ALA ALA B . n 
B 1 123 THR 123 102 102 THR THR B . n 
B 1 124 ALA 124 103 103 ALA ALA B . n 
B 1 125 GLU 125 104 104 GLU GLU B . n 
B 1 126 THR 126 105 105 THR THR B . n 
B 1 127 TRP 127 106 106 TRP TRP B . n 
B 1 128 ASP 128 107 107 ASP ASP B . n 
B 1 129 ASN 129 108 108 ASN ASN B . n 
B 1 130 GLY 130 109 109 GLY GLY B . n 
B 1 131 LYS 131 110 110 LYS LYS B . n 
B 1 132 PRO 132 111 111 PRO PRO B . n 
B 1 133 ILE 133 112 112 ILE ILE B . n 
B 1 134 ARG 134 113 113 ARG ARG B . n 
B 1 135 GLU 135 114 114 GLU GLU B . n 
B 1 136 THR 136 115 115 THR THR B . n 
B 1 137 MET 137 116 116 MET MET B . n 
B 1 138 ALA 138 117 117 ALA ALA B . n 
B 1 139 ALA 139 118 118 ALA ALA B . n 
B 1 140 ASP 140 119 119 ASP ASP B . n 
B 1 141 LEU 141 120 120 LEU LEU B . n 
B 1 142 PRO 142 121 121 PRO PRO B . n 
B 1 143 LEU 143 122 122 LEU LEU B . n 
B 1 144 ALA 144 123 123 ALA ALA B . n 
B 1 145 ILE 145 124 124 ILE ILE B . n 
B 1 146 ASP 146 125 125 ASP ASP B . n 
B 1 147 HIS 147 126 126 HIS HIS B . n 
B 1 148 PHE 148 127 127 PHE PHE B . n 
B 1 149 ARG 149 128 128 ARG ARG B . n 
B 1 150 TYR 150 129 129 TYR TYR B . n 
B 1 151 PHE 151 130 130 PHE PHE B . n 
B 1 152 ALA 152 131 131 ALA ALA B . n 
B 1 153 GLY 153 132 132 GLY GLY B . n 
B 1 154 VAL 154 133 133 VAL VAL B . n 
B 1 155 LEU 155 134 134 LEU LEU B . n 
B 1 156 ARG 156 135 135 ARG ARG B . n 
B 1 157 ALA 157 136 136 ALA ALA B . n 
B 1 158 GLN 158 137 137 GLN GLN B . n 
B 1 159 GLU 159 138 138 GLU GLU B . n 
B 1 160 GLY 160 139 139 GLY GLY B . n 
B 1 161 SER 161 140 140 SER SER B . n 
B 1 162 ILE 162 141 141 ILE ILE B . n 
B 1 163 SER 163 142 142 SER SER B . n 
B 1 164 GLN 164 143 143 GLN GLN B . n 
B 1 165 ILE 165 144 144 ILE ILE B . n 
B 1 166 ASP 166 145 145 ASP ASP B . n 
B 1 167 ASP 167 146 146 ASP ASP B . n 
B 1 168 ASP 168 147 147 ASP ASP B . n 
B 1 169 THR 169 148 148 THR THR B . n 
B 1 170 VAL 170 149 149 VAL VAL B . n 
B 1 171 ALA 171 150 150 ALA ALA B . n 
B 1 172 TYR 172 151 151 TYR TYR B . n 
B 1 173 HIS 173 152 152 HIS HIS B . n 
B 1 174 PHE 174 153 153 PHE PHE B . n 
B 1 175 HIS 175 154 154 HIS HIS B . n 
B 1 176 GLU 176 155 155 GLU GLU B . n 
B 1 177 PRO 177 156 156 PRO PRO B . n 
B 1 178 LEU 178 157 157 LEU LEU B . n 
B 1 179 GLY 179 158 158 GLY GLY B . n 
B 1 180 VAL 180 159 159 VAL VAL B . n 
B 1 181 VAL 181 160 160 VAL VAL B . n 
B 1 182 GLY 182 161 161 GLY GLY B . n 
B 1 183 GLN 183 162 162 GLN GLN B . n 
B 1 184 ILE 184 163 163 ILE ILE B . n 
B 1 185 ILE 185 164 164 ILE ILE B . n 
B 1 186 PRO 186 165 165 PRO PRO B . n 
B 1 187 TRP 187 166 166 TRP TRP B . n 
B 1 188 ASN 188 167 167 ASN ASN B . n 
B 1 189 PHE 189 168 168 PHE PHE B . n 
B 1 190 PRO 190 169 169 PRO PRO B . n 
B 1 191 LEU 191 170 170 LEU LEU B . n 
B 1 192 LEU 192 171 171 LEU LEU B . n 
B 1 193 MET 193 172 172 MET MET B . n 
B 1 194 ALA 194 173 173 ALA ALA B . n 
B 1 195 CYS 195 174 174 CYS CYS B . n 
B 1 196 TRP 196 175 175 TRP TRP B . n 
B 1 197 LYS 197 176 176 LYS LYS B . n 
B 1 198 LEU 198 177 177 LEU LEU B . n 
B 1 199 ALA 199 178 178 ALA ALA B . n 
B 1 200 PRO 200 179 179 PRO PRO B . n 
B 1 201 ALA 201 180 180 ALA ALA B . n 
B 1 202 ILE 202 181 181 ILE ILE B . n 
B 1 203 ALA 203 182 182 ALA ALA B . n 
B 1 204 ALA 204 183 183 ALA ALA B . n 
B 1 205 GLY 205 184 184 GLY GLY B . n 
B 1 206 ASN 206 185 185 ASN ASN B . n 
B 1 207 CYS 207 186 186 CYS CYS B . n 
B 1 208 VAL 208 187 187 VAL VAL B . n 
B 1 209 VAL 209 188 188 VAL VAL B . n 
B 1 210 LEU 210 189 189 LEU LEU B . n 
B 1 211 LYS 211 190 190 LYS LYS B . n 
B 1 212 PRO 212 191 191 PRO PRO B . n 
B 1 213 ALA 213 192 192 ALA ALA B . n 
B 1 214 GLU 214 193 193 GLU GLU B . n 
B 1 215 GLN 215 194 194 GLN GLN B . n 
B 1 216 THR 216 195 195 THR THR B . n 
B 1 217 PRO 217 196 196 PRO PRO B . n 
B 1 218 ALA 218 197 197 ALA ALA B . n 
B 1 219 GLY 219 198 198 GLY GLY B . n 
B 1 220 ILE 220 199 199 ILE ILE B . n 
B 1 221 MET 221 200 200 MET MET B . n 
B 1 222 VAL 222 201 201 VAL VAL B . n 
B 1 223 TRP 223 202 202 TRP TRP B . n 
B 1 224 ALA 224 203 203 ALA ALA B . n 
B 1 225 ASN 225 204 204 ASN ASN B . n 
B 1 226 LEU 226 205 205 LEU LEU B . n 
B 1 227 ILE 227 206 206 ILE ILE B . n 
B 1 228 GLY 228 207 207 GLY GLY B . n 
B 1 229 ASP 229 208 208 ASP ASP B . n 
B 1 230 LEU 230 209 209 LEU LEU B . n 
B 1 231 LEU 231 210 210 LEU LEU B . n 
B 1 232 PRO 232 211 211 PRO PRO B . n 
B 1 233 PRO 233 212 212 PRO PRO B . n 
B 1 234 GLY 234 213 213 GLY GLY B . n 
B 1 235 VAL 235 214 214 VAL VAL B . n 
B 1 236 LEU 236 215 215 LEU LEU B . n 
B 1 237 ASN 237 216 216 ASN ASN B . n 
B 1 238 ILE 238 217 217 ILE ILE B . n 
B 1 239 VAL 239 218 218 VAL VAL B . n 
B 1 240 ASN 240 219 219 ASN ASN B . n 
B 1 241 GLY 241 220 220 GLY GLY B . n 
B 1 242 PHE 242 221 221 PHE PHE B . n 
B 1 243 GLY 243 222 222 GLY GLY B . n 
B 1 244 LEU 244 223 223 LEU LEU B . n 
B 1 245 GLU 245 224 224 GLU GLU B . n 
B 1 246 ALA 246 225 225 ALA ALA B . n 
B 1 247 GLY 247 226 226 GLY GLY B . n 
B 1 248 LYS 248 227 227 LYS LYS B . n 
B 1 249 PRO 249 228 228 PRO PRO B . n 
B 1 250 LEU 250 229 229 LEU LEU B . n 
B 1 251 ALA 251 230 230 ALA ALA B . n 
B 1 252 SER 252 231 231 SER SER B . n 
B 1 253 SER 253 232 232 SER SER B . n 
B 1 254 ASN 254 233 233 ASN ASN B . n 
B 1 255 ARG 255 234 234 ARG ARG B . n 
B 1 256 ILE 256 235 235 ILE ILE B . n 
B 1 257 ALA 257 236 236 ALA ALA B . n 
B 1 258 LYS 258 237 237 LYS LYS B . n 
B 1 259 ILE 259 238 238 ILE ILE B . n 
B 1 260 ALA 260 239 239 ALA ALA B . n 
B 1 261 PHE 261 240 240 PHE PHE B . n 
B 1 262 THR 262 241 241 THR THR B . n 
B 1 263 GLY 263 242 242 GLY GLY B . n 
B 1 264 GLU 264 243 243 GLU GLU B . n 
B 1 265 THR 265 244 244 THR THR B . n 
B 1 266 THR 266 245 245 THR THR B . n 
B 1 267 THR 267 246 246 THR THR B . n 
B 1 268 GLY 268 247 247 GLY GLY B . n 
B 1 269 ARG 269 248 248 ARG ARG B . n 
B 1 270 LEU 270 249 249 LEU LEU B . n 
B 1 271 ILE 271 250 250 ILE ILE B . n 
B 1 272 MET 272 251 251 MET MET B . n 
B 1 273 GLN 273 252 252 GLN GLN B . n 
B 1 274 TYR 274 253 253 TYR TYR B . n 
B 1 275 ALA 275 254 254 ALA ALA B . n 
B 1 276 SER 276 255 255 SER SER B . n 
B 1 277 GLU 277 256 256 GLU GLU B . n 
B 1 278 ASN 278 257 257 ASN ASN B . n 
B 1 279 LEU 279 258 258 LEU LEU B . n 
B 1 280 ILE 280 259 259 ILE ILE B . n 
B 1 281 PRO 281 260 260 PRO PRO B . n 
B 1 282 VAL 282 261 261 VAL VAL B . n 
B 1 283 THR 283 262 262 THR THR B . n 
B 1 284 LEU 284 263 263 LEU LEU B . n 
B 1 285 GLU 285 264 264 GLU GLU B . n 
B 1 286 LEU 286 265 265 LEU LEU B . n 
B 1 287 GLY 287 266 266 GLY GLY B . n 
B 1 288 GLY 288 267 267 GLY GLY B . n 
B 1 289 LYS 289 268 268 LYS LYS B . n 
B 1 290 SER 290 269 269 SER SER B . n 
B 1 291 PRO 291 270 270 PRO PRO B . n 
B 1 292 ASN 292 271 271 ASN ASN B . n 
B 1 293 ILE 293 272 272 ILE ILE B . n 
B 1 294 PHE 294 273 273 PHE PHE B . n 
B 1 295 PHE 295 274 274 PHE PHE B . n 
B 1 296 ALA 296 275 275 ALA ALA B . n 
B 1 297 ASP 297 276 276 ASP ASP B . n 
B 1 298 VAL 298 277 277 VAL VAL B . n 
B 1 299 ALA 299 278 278 ALA ALA B . n 
B 1 300 ARG 300 279 279 ARG ARG B . n 
B 1 301 GLU 301 280 280 GLU GLU B . n 
B 1 302 ASP 302 281 281 ASP ASP B . n 
B 1 303 ASP 303 282 282 ASP ASP B . n 
B 1 304 ASP 304 283 283 ASP ASP B . n 
B 1 305 PHE 305 284 284 PHE PHE B . n 
B 1 306 PHE 306 285 285 PHE PHE B . n 
B 1 307 ASP 307 286 286 ASP ASP B . n 
B 1 308 LYS 308 287 287 LYS LYS B . n 
B 1 309 ALA 309 288 288 ALA ALA B . n 
B 1 310 LEU 310 289 289 LEU LEU B . n 
B 1 311 GLU 311 290 290 GLU GLU B . n 
B 1 312 GLY 312 291 291 GLY GLY B . n 
B 1 313 PHE 313 292 292 PHE PHE B . n 
B 1 314 THR 314 293 293 THR THR B . n 
B 1 315 MET 315 294 294 MET MET B . n 
B 1 316 PHE 316 295 295 PHE PHE B . n 
B 1 317 ALA 317 296 296 ALA ALA B . n 
B 1 318 LEU 318 297 297 LEU LEU B . n 
B 1 319 ASN 319 298 298 ASN ASN B . n 
B 1 320 GLN 320 299 299 GLN GLN B . n 
B 1 321 GLY 321 300 300 GLY GLY B . n 
B 1 322 GLU 322 301 301 GLU GLU B . n 
B 1 323 VAL 323 302 302 VAL VAL B . n 
B 1 324 CYS 324 303 303 CYS CYS B . n 
B 1 325 THR 325 304 304 THR THR B . n 
B 1 326 CYS 326 305 305 CYS CYS B . n 
B 1 327 PRO 327 306 306 PRO PRO B . n 
B 1 328 SER 328 307 307 SER SER B . n 
B 1 329 ARG 329 308 308 ARG ARG B . n 
B 1 330 VAL 330 309 309 VAL VAL B . n 
B 1 331 LEU 331 310 310 LEU LEU B . n 
B 1 332 ILE 332 311 311 ILE ILE B . n 
B 1 333 GLN 333 312 312 GLN GLN B . n 
B 1 334 GLU 334 313 313 GLU GLU B . n 
B 1 335 SER 335 314 314 SER SER B . n 
B 1 336 ILE 336 315 315 ILE ILE B . n 
B 1 337 TYR 337 316 316 TYR TYR B . n 
B 1 338 ASP 338 317 317 ASP ASP B . n 
B 1 339 LYS 339 318 318 LYS LYS B . n 
B 1 340 PHE 340 319 319 PHE PHE B . n 
B 1 341 MET 341 320 320 MET MET B . n 
B 1 342 GLU 342 321 321 GLU GLU B . n 
B 1 343 ARG 343 322 322 ARG ARG B . n 
B 1 344 ALA 344 323 323 ALA ALA B . n 
B 1 345 VAL 345 324 324 VAL VAL B . n 
B 1 346 GLN 346 325 325 GLN GLN B . n 
B 1 347 ARG 347 326 326 ARG ARG B . n 
B 1 348 VAL 348 327 327 VAL VAL B . n 
B 1 349 GLN 349 328 328 GLN GLN B . n 
B 1 350 ALA 350 329 329 ALA ALA B . n 
B 1 351 ILE 351 330 330 ILE ILE B . n 
B 1 352 LYS 352 331 331 LYS LYS B . n 
B 1 353 GLN 353 332 332 GLN GLN B . n 
B 1 354 GLY 354 333 333 GLY GLY B . n 
B 1 355 ASP 355 334 334 ASP ASP B . n 
B 1 356 PRO 356 335 335 PRO PRO B . n 
B 1 357 ARG 357 336 336 ARG ARG B . n 
B 1 358 GLU 358 337 337 GLU GLU B . n 
B 1 359 SER 359 338 338 SER SER B . n 
B 1 360 ASP 360 339 339 ASP ASP B . n 
B 1 361 THR 361 340 340 THR THR B . n 
B 1 362 MET 362 341 341 MET MET B . n 
B 1 363 ILE 363 342 342 ILE ILE B . n 
B 1 364 GLY 364 343 343 GLY GLY B . n 
B 1 365 ALA 365 344 344 ALA ALA B . n 
B 1 366 GLN 366 345 345 GLN GLN B . n 
B 1 367 ALA 367 346 346 ALA ALA B . n 
B 1 368 SER 368 347 347 SER SER B . n 
B 1 369 SER 369 348 348 SER SER B . n 
B 1 370 GLU 370 349 349 GLU GLU B . n 
B 1 371 GLN 371 350 350 GLN GLN B . n 
B 1 372 LYS 372 351 351 LYS LYS B . n 
B 1 373 GLU 373 352 352 GLU GLU B . n 
B 1 374 LYS 374 353 353 LYS LYS B . n 
B 1 375 ILE 375 354 354 ILE ILE B . n 
B 1 376 LEU 376 355 355 LEU LEU B . n 
B 1 377 SER 377 356 356 SER SER B . n 
B 1 378 TYR 378 357 357 TYR TYR B . n 
B 1 379 LEU 379 358 358 LEU LEU B . n 
B 1 380 ASP 380 359 359 ASP ASP B . n 
B 1 381 ILE 381 360 360 ILE ILE B . n 
B 1 382 GLY 382 361 361 GLY GLY B . n 
B 1 383 LYS 383 362 362 LYS LYS B . n 
B 1 384 LYS 384 363 363 LYS LYS B . n 
B 1 385 GLU 385 364 364 GLU GLU B . n 
B 1 386 GLY 386 365 365 GLY GLY B . n 
B 1 387 ALA 387 366 366 ALA ALA B . n 
B 1 388 GLU 388 367 367 GLU GLU B . n 
B 1 389 VAL 389 368 368 VAL VAL B . n 
B 1 390 LEU 390 369 369 LEU LEU B . n 
B 1 391 THR 391 370 370 THR THR B . n 
B 1 392 GLY 392 371 371 GLY GLY B . n 
B 1 393 GLY 393 372 372 GLY GLY B . n 
B 1 394 LYS 394 373 373 LYS LYS B . n 
B 1 395 ALA 395 374 374 ALA ALA B . n 
B 1 396 ALA 396 375 375 ALA ALA B . n 
B 1 397 ASP 397 376 376 ASP ASP B . n 
B 1 398 LEU 398 377 377 LEU LEU B . n 
B 1 399 GLY 399 378 378 GLY GLY B . n 
B 1 400 GLY 400 379 379 GLY GLY B . n 
B 1 401 GLU 401 380 380 GLU GLU B . n 
B 1 402 LEU 402 381 381 LEU LEU B . n 
B 1 403 SER 403 382 382 SER SER B . n 
B 1 404 GLY 404 383 383 GLY GLY B . n 
B 1 405 GLY 405 384 384 GLY GLY B . n 
B 1 406 TYR 406 385 385 TYR TYR B . n 
B 1 407 TYR 407 386 386 TYR TYR B . n 
B 1 408 ILE 408 387 387 ILE ILE B . n 
B 1 409 GLU 409 388 388 GLU GLU B . n 
B 1 410 PRO 410 389 389 PRO PRO B . n 
B 1 411 THR 411 390 390 THR THR B . n 
B 1 412 ILE 412 391 391 ILE ILE B . n 
B 1 413 PHE 413 392 392 PHE PHE B . n 
B 1 414 ARG 414 393 393 ARG ARG B . n 
B 1 415 GLY 415 394 394 GLY GLY B . n 
B 1 416 ASN 416 395 395 ASN ASN B . n 
B 1 417 ASN 417 396 396 ASN ASN B . n 
B 1 418 LYS 418 397 397 LYS LYS B . n 
B 1 419 MET 419 398 398 MET MET B . n 
B 1 420 ARG 420 399 399 ARG ARG B . n 
B 1 421 ILE 421 400 400 ILE ILE B . n 
B 1 422 PHE 422 401 401 PHE PHE B . n 
B 1 423 GLN 423 402 402 GLN GLN B . n 
B 1 424 GLU 424 403 403 GLU GLU B . n 
B 1 425 GLU 425 404 404 GLU GLU B . n 
B 1 426 ILE 426 405 405 ILE ILE B . n 
B 1 427 PHE 427 406 406 PHE PHE B . n 
B 1 428 GLY 428 407 407 GLY GLY B . n 
B 1 429 PRO 429 408 408 PRO PRO B . n 
B 1 430 VAL 430 409 409 VAL VAL B . n 
B 1 431 VAL 431 410 410 VAL VAL B . n 
B 1 432 SER 432 411 411 SER SER B . n 
B 1 433 VAL 433 412 412 VAL VAL B . n 
B 1 434 THR 434 413 413 THR THR B . n 
B 1 435 THR 435 414 414 THR THR B . n 
B 1 436 PHE 436 415 415 PHE PHE B . n 
B 1 437 LYS 437 416 416 LYS LYS B . n 
B 1 438 ASP 438 417 417 ASP ASP B . n 
B 1 439 GLN 439 418 418 GLN GLN B . n 
B 1 440 ALA 440 419 419 ALA ALA B . n 
B 1 441 GLU 441 420 420 GLU GLU B . n 
B 1 442 ALA 442 421 421 ALA ALA B . n 
B 1 443 LEU 443 422 422 LEU LEU B . n 
B 1 444 GLU 444 423 423 GLU GLU B . n 
B 1 445 ILE 445 424 424 ILE ILE B . n 
B 1 446 ALA 446 425 425 ALA ALA B . n 
B 1 447 ASN 447 426 426 ASN ASN B . n 
B 1 448 ASP 448 427 427 ASP ASP B . n 
B 1 449 THR 449 428 428 THR THR B . n 
B 1 450 LEU 450 429 429 LEU LEU B . n 
B 1 451 TYR 451 430 430 TYR TYR B . n 
B 1 452 GLY 452 431 431 GLY GLY B . n 
B 1 453 LEU 453 432 432 LEU LEU B . n 
B 1 454 GLY 454 433 433 GLY GLY B . n 
B 1 455 ALA 455 434 434 ALA ALA B . n 
B 1 456 GLY 456 435 435 GLY GLY B . n 
B 1 457 VAL 457 436 436 VAL VAL B . n 
B 1 458 TRP 458 437 437 TRP TRP B . n 
B 1 459 SER 459 438 438 SER SER B . n 
B 1 460 ARG 460 439 439 ARG ARG B . n 
B 1 461 ASP 461 440 440 ASP ASP B . n 
B 1 462 ALA 462 441 441 ALA ALA B . n 
B 1 463 ASN 463 442 442 ASN ASN B . n 
B 1 464 THR 464 443 443 THR THR B . n 
B 1 465 CYS 465 444 444 CYS CYS B . n 
B 1 466 TYR 466 445 445 TYR TYR B . n 
B 1 467 ARG 467 446 446 ARG ARG B . n 
B 1 468 MET 468 447 447 MET MET B . n 
B 1 469 GLY 469 448 448 GLY GLY B . n 
B 1 470 ARG 470 449 449 ARG ARG B . n 
B 1 471 GLY 471 450 450 GLY GLY B . n 
B 1 472 ILE 472 451 451 ILE ILE B . n 
B 1 473 LYS 473 452 452 LYS LYS B . n 
B 1 474 ALA 474 453 453 ALA ALA B . n 
B 1 475 GLY 475 454 454 GLY GLY B . n 
B 1 476 ARG 476 455 455 ARG ARG B . n 
B 1 477 VAL 477 456 456 VAL VAL B . n 
B 1 478 TRP 478 457 457 TRP TRP B . n 
B 1 479 THR 479 458 458 THR THR B . n 
B 1 480 ASN 480 459 459 ASN ASN B . n 
B 1 481 CYS 481 460 460 CYS CYS B . n 
B 1 482 TYR 482 461 461 TYR TYR B . n 
B 1 483 HIS 483 462 462 HIS HIS B . n 
B 1 484 ALA 484 463 463 ALA ALA B . n 
B 1 485 TYR 485 464 464 TYR TYR B . n 
B 1 486 PRO 486 465 465 PRO PRO B . n 
B 1 487 ALA 487 466 466 ALA ALA B . n 
B 1 488 HIS 488 467 467 HIS HIS B . n 
B 1 489 ALA 489 468 468 ALA ALA B . n 
B 1 490 ALA 490 469 469 ALA ALA B . n 
B 1 491 PHE 491 470 470 PHE PHE B . n 
B 1 492 GLY 492 471 471 GLY GLY B . n 
B 1 493 GLY 493 472 472 GLY GLY B . n 
B 1 494 TYR 494 473 473 TYR TYR B . n 
B 1 495 LYS 495 474 474 LYS LYS B . n 
B 1 496 GLN 496 475 475 GLN GLN B . n 
B 1 497 SER 497 476 476 SER SER B . n 
B 1 498 GLY 498 477 477 GLY GLY B . n 
B 1 499 ILE 499 478 478 ILE ILE B . n 
B 1 500 GLY 500 479 479 GLY GLY B . n 
B 1 501 ARG 501 480 480 ARG ARG B . n 
B 1 502 GLU 502 481 481 GLU GLU B . n 
B 1 503 THR 503 482 482 THR THR B . n 
B 1 504 HIS 504 483 483 HIS HIS B . n 
B 1 505 LYS 505 484 484 LYS LYS B . n 
B 1 506 MET 506 485 485 MET MET B . n 
B 1 507 MET 507 486 486 MET MET B . n 
B 1 508 LEU 508 487 487 LEU LEU B . n 
B 1 509 ASP 509 488 488 ASP ASP B . n 
B 1 510 HIS 510 489 489 HIS HIS B . n 
B 1 511 TYR 511 490 490 TYR TYR B . n 
B 1 512 GLN 512 491 491 GLN GLN B . n 
B 1 513 GLN 513 492 492 GLN GLN B . n 
B 1 514 THR 514 493 493 THR THR B . n 
B 1 515 LYS 515 494 494 LYS LYS B . n 
B 1 516 ASN 516 495 495 ASN ASN B . n 
B 1 517 MET 517 496 496 MET MET B . n 
B 1 518 LEU 518 497 497 LEU LEU B . n 
B 1 519 VAL 519 498 498 VAL VAL B . n 
B 1 520 SER 520 499 499 SER SER B . n 
B 1 521 TYR 521 500 500 TYR TYR B . n 
B 1 522 SER 522 501 501 SER SER B . n 
B 1 523 PRO 523 502 502 PRO PRO B . n 
B 1 524 LYS 524 503 503 LYS LYS B . n 
B 1 525 LYS 525 504 504 LYS LYS B . n 
B 1 526 LEU 526 505 505 LEU LEU B . n 
B 1 527 GLY 527 506 506 GLY GLY B . n 
B 1 528 PHE 528 507 507 PHE PHE B . n 
B 1 529 PHE 529 508 508 PHE PHE B . n 
C 1 1   MET 1   -20 ?   ?   ?   C . n 
C 1 2   GLY 2   -19 ?   ?   ?   C . n 
C 1 3   HIS 3   -18 ?   ?   ?   C . n 
C 1 4   HIS 4   -17 ?   ?   ?   C . n 
C 1 5   HIS 5   -16 ?   ?   ?   C . n 
C 1 6   HIS 6   -15 ?   ?   ?   C . n 
C 1 7   HIS 7   -14 ?   ?   ?   C . n 
C 1 8   HIS 8   -13 ?   ?   ?   C . n 
C 1 9   HIS 9   -12 ?   ?   ?   C . n 
C 1 10  HIS 10  -11 ?   ?   ?   C . n 
C 1 11  HIS 11  -10 ?   ?   ?   C . n 
C 1 12  HIS 12  -9  ?   ?   ?   C . n 
C 1 13  SER 13  -8  ?   ?   ?   C . n 
C 1 14  SER 14  -7  ?   ?   ?   C . n 
C 1 15  GLY 15  -6  ?   ?   ?   C . n 
C 1 16  HIS 16  -5  ?   ?   ?   C . n 
C 1 17  ILE 17  -4  ?   ?   ?   C . n 
C 1 18  GLU 18  -3  ?   ?   ?   C . n 
C 1 19  GLY 19  -2  ?   ?   ?   C . n 
C 1 20  ARG 20  -1  ?   ?   ?   C . n 
C 1 21  HIS 21  0   ?   ?   ?   C . n 
C 1 22  MET 22  1   ?   ?   ?   C . n 
C 1 23  PRO 23  2   ?   ?   ?   C . n 
C 1 24  ASN 24  3   ?   ?   ?   C . n 
C 1 25  ASP 25  4   ?   ?   ?   C . n 
C 1 26  GLN 26  5   ?   ?   ?   C . n 
C 1 27  THR 27  6   ?   ?   ?   C . n 
C 1 28  HIS 28  7   ?   ?   ?   C . n 
C 1 29  PRO 29  8   ?   ?   ?   C . n 
C 1 30  PHE 30  9   ?   ?   ?   C . n 
C 1 31  ARG 31  10  ?   ?   ?   C . n 
C 1 32  GLY 32  11  11  GLY GLY C . n 
C 1 33  VAL 33  12  12  VAL VAL C . n 
C 1 34  ASN 34  13  13  ASN ASN C . n 
C 1 35  ALA 35  14  14  ALA ALA C . n 
C 1 36  LEU 36  15  15  LEU LEU C . n 
C 1 37  PRO 37  16  16  PRO PRO C . n 
C 1 38  PHE 38  17  17  PHE PHE C . n 
C 1 39  GLU 39  18  18  GLU GLU C . n 
C 1 40  GLU 40  19  19  GLU GLU C . n 
C 1 41  ARG 41  20  20  ARG ARG C . n 
C 1 42  TYR 42  21  21  TYR TYR C . n 
C 1 43  ASP 43  22  22  ASP ASP C . n 
C 1 44  ASN 44  23  23  ASN ASN C . n 
C 1 45  PHE 45  24  24  PHE PHE C . n 
C 1 46  ILE 46  25  25  ILE ILE C . n 
C 1 47  GLY 47  26  26  GLY GLY C . n 
C 1 48  GLY 48  27  27  GLY GLY C . n 
C 1 49  GLU 49  28  28  GLU GLU C . n 
C 1 50  TRP 50  29  29  TRP TRP C . n 
C 1 51  VAL 51  30  30  VAL VAL C . n 
C 1 52  ALA 52  31  31  ALA ALA C . n 
C 1 53  PRO 53  32  32  PRO PRO C . n 
C 1 54  VAL 54  33  33  VAL VAL C . n 
C 1 55  SER 55  34  34  SER SER C . n 
C 1 56  GLY 56  35  35  GLY GLY C . n 
C 1 57  ARG 57  36  36  ARG ARG C . n 
C 1 58  TYR 58  37  37  TYR TYR C . n 
C 1 59  PHE 59  38  38  PHE PHE C . n 
C 1 60  THR 60  39  39  THR THR C . n 
C 1 61  ASN 61  40  40  ASN ASN C . n 
C 1 62  THR 62  41  41  THR THR C . n 
C 1 63  THR 63  42  42  THR THR C . n 
C 1 64  PRO 64  43  43  PRO PRO C . n 
C 1 65  ILE 65  44  44  ILE ILE C . n 
C 1 66  THR 66  45  45  THR THR C . n 
C 1 67  GLY 67  46  46  GLY GLY C . n 
C 1 68  ALA 68  47  47  ALA ALA C . n 
C 1 69  GLU 69  48  48  GLU GLU C . n 
C 1 70  ILE 70  49  49  ILE ILE C . n 
C 1 71  GLY 71  50  50  GLY GLY C . n 
C 1 72  GLN 72  51  51  GLN GLN C . n 
C 1 73  ILE 73  52  52  ILE ILE C . n 
C 1 74  ALA 74  53  53  ALA ALA C . n 
C 1 75  ARG 75  54  54  ARG ARG C . n 
C 1 76  SER 76  55  55  SER SER C . n 
C 1 77  GLU 77  56  56  GLU GLU C . n 
C 1 78  ALA 78  57  57  ALA ALA C . n 
C 1 79  GLY 79  58  58  GLY GLY C . n 
C 1 80  ASP 80  59  59  ASP ASP C . n 
C 1 81  ILE 81  60  60  ILE ILE C . n 
C 1 82  GLU 82  61  61  GLU GLU C . n 
C 1 83  LEU 83  62  62  LEU LEU C . n 
C 1 84  ALA 84  63  63  ALA ALA C . n 
C 1 85  LEU 85  64  64  LEU LEU C . n 
C 1 86  ASP 86  65  65  ASP ASP C . n 
C 1 87  ALA 87  66  66  ALA ALA C . n 
C 1 88  ALA 88  67  67  ALA ALA C . n 
C 1 89  HIS 89  68  68  HIS HIS C . n 
C 1 90  ALA 90  69  69  ALA ALA C . n 
C 1 91  ALA 91  70  70  ALA ALA C . n 
C 1 92  LYS 92  71  71  LYS LYS C . n 
C 1 93  GLU 93  72  72  GLU GLU C . n 
C 1 94  LYS 94  73  73  LYS LYS C . n 
C 1 95  TRP 95  74  74  TRP TRP C . n 
C 1 96  GLY 96  75  75  GLY GLY C . n 
C 1 97  ALA 97  76  76  ALA ALA C . n 
C 1 98  THR 98  77  77  THR THR C . n 
C 1 99  SER 99  78  78  SER SER C . n 
C 1 100 PRO 100 79  79  PRO PRO C . n 
C 1 101 ALA 101 80  80  ALA ALA C . n 
C 1 102 GLU 102 81  81  GLU GLU C . n 
C 1 103 ARG 103 82  82  ARG ARG C . n 
C 1 104 ALA 104 83  83  ALA ALA C . n 
C 1 105 ASN 105 84  84  ASN ASN C . n 
C 1 106 ILE 106 85  85  ILE ILE C . n 
C 1 107 MET 107 86  86  MET MET C . n 
C 1 108 LEU 108 87  87  LEU LEU C . n 
C 1 109 LYS 109 88  88  LYS LYS C . n 
C 1 110 ILE 110 89  89  ILE ILE C . n 
C 1 111 ALA 111 90  90  ALA ALA C . n 
C 1 112 ASP 112 91  91  ASP ASP C . n 
C 1 113 ARG 113 92  92  ARG ARG C . n 
C 1 114 MET 114 93  93  MET MET C . n 
C 1 115 GLU 115 94  94  GLU GLU C . n 
C 1 116 ARG 116 95  95  ARG ARG C . n 
C 1 117 ASN 117 96  96  ASN ASN C . n 
C 1 118 LEU 118 97  97  LEU LEU C . n 
C 1 119 GLU 119 98  98  GLU GLU C . n 
C 1 120 LEU 120 99  99  LEU LEU C . n 
C 1 121 LEU 121 100 100 LEU LEU C . n 
C 1 122 ALA 122 101 101 ALA ALA C . n 
C 1 123 THR 123 102 102 THR THR C . n 
C 1 124 ALA 124 103 103 ALA ALA C . n 
C 1 125 GLU 125 104 104 GLU GLU C . n 
C 1 126 THR 126 105 105 THR THR C . n 
C 1 127 TRP 127 106 106 TRP TRP C . n 
C 1 128 ASP 128 107 107 ASP ASP C . n 
C 1 129 ASN 129 108 108 ASN ASN C . n 
C 1 130 GLY 130 109 109 GLY GLY C . n 
C 1 131 LYS 131 110 110 LYS LYS C . n 
C 1 132 PRO 132 111 111 PRO PRO C . n 
C 1 133 ILE 133 112 112 ILE ILE C . n 
C 1 134 ARG 134 113 113 ARG ARG C . n 
C 1 135 GLU 135 114 114 GLU GLU C . n 
C 1 136 THR 136 115 115 THR THR C . n 
C 1 137 MET 137 116 116 MET MET C . n 
C 1 138 ALA 138 117 117 ALA ALA C . n 
C 1 139 ALA 139 118 118 ALA ALA C . n 
C 1 140 ASP 140 119 119 ASP ASP C . n 
C 1 141 LEU 141 120 120 LEU LEU C . n 
C 1 142 PRO 142 121 121 PRO PRO C . n 
C 1 143 LEU 143 122 122 LEU LEU C . n 
C 1 144 ALA 144 123 123 ALA ALA C . n 
C 1 145 ILE 145 124 124 ILE ILE C . n 
C 1 146 ASP 146 125 125 ASP ASP C . n 
C 1 147 HIS 147 126 126 HIS HIS C . n 
C 1 148 PHE 148 127 127 PHE PHE C . n 
C 1 149 ARG 149 128 128 ARG ARG C . n 
C 1 150 TYR 150 129 129 TYR TYR C . n 
C 1 151 PHE 151 130 130 PHE PHE C . n 
C 1 152 ALA 152 131 131 ALA ALA C . n 
C 1 153 GLY 153 132 132 GLY GLY C . n 
C 1 154 VAL 154 133 133 VAL VAL C . n 
C 1 155 LEU 155 134 134 LEU LEU C . n 
C 1 156 ARG 156 135 135 ARG ARG C . n 
C 1 157 ALA 157 136 136 ALA ALA C . n 
C 1 158 GLN 158 137 137 GLN GLN C . n 
C 1 159 GLU 159 138 138 GLU GLU C . n 
C 1 160 GLY 160 139 139 GLY GLY C . n 
C 1 161 SER 161 140 140 SER SER C . n 
C 1 162 ILE 162 141 141 ILE ILE C . n 
C 1 163 SER 163 142 142 SER SER C . n 
C 1 164 GLN 164 143 143 GLN GLN C . n 
C 1 165 ILE 165 144 144 ILE ILE C . n 
C 1 166 ASP 166 145 145 ASP ASP C . n 
C 1 167 ASP 167 146 146 ASP ASP C . n 
C 1 168 ASP 168 147 147 ASP ASP C . n 
C 1 169 THR 169 148 148 THR THR C . n 
C 1 170 VAL 170 149 149 VAL VAL C . n 
C 1 171 ALA 171 150 150 ALA ALA C . n 
C 1 172 TYR 172 151 151 TYR TYR C . n 
C 1 173 HIS 173 152 152 HIS HIS C . n 
C 1 174 PHE 174 153 153 PHE PHE C . n 
C 1 175 HIS 175 154 154 HIS HIS C . n 
C 1 176 GLU 176 155 155 GLU GLU C . n 
C 1 177 PRO 177 156 156 PRO PRO C . n 
C 1 178 LEU 178 157 157 LEU LEU C . n 
C 1 179 GLY 179 158 158 GLY GLY C . n 
C 1 180 VAL 180 159 159 VAL VAL C . n 
C 1 181 VAL 181 160 160 VAL VAL C . n 
C 1 182 GLY 182 161 161 GLY GLY C . n 
C 1 183 GLN 183 162 162 GLN GLN C . n 
C 1 184 ILE 184 163 163 ILE ILE C . n 
C 1 185 ILE 185 164 164 ILE ILE C . n 
C 1 186 PRO 186 165 165 PRO PRO C . n 
C 1 187 TRP 187 166 166 TRP TRP C . n 
C 1 188 ASN 188 167 167 ASN ASN C . n 
C 1 189 PHE 189 168 168 PHE PHE C . n 
C 1 190 PRO 190 169 169 PRO PRO C . n 
C 1 191 LEU 191 170 170 LEU LEU C . n 
C 1 192 LEU 192 171 171 LEU LEU C . n 
C 1 193 MET 193 172 172 MET MET C . n 
C 1 194 ALA 194 173 173 ALA ALA C . n 
C 1 195 CYS 195 174 174 CYS CYS C . n 
C 1 196 TRP 196 175 175 TRP TRP C . n 
C 1 197 LYS 197 176 176 LYS LYS C . n 
C 1 198 LEU 198 177 177 LEU LEU C . n 
C 1 199 ALA 199 178 178 ALA ALA C . n 
C 1 200 PRO 200 179 179 PRO PRO C . n 
C 1 201 ALA 201 180 180 ALA ALA C . n 
C 1 202 ILE 202 181 181 ILE ILE C . n 
C 1 203 ALA 203 182 182 ALA ALA C . n 
C 1 204 ALA 204 183 183 ALA ALA C . n 
C 1 205 GLY 205 184 184 GLY GLY C . n 
C 1 206 ASN 206 185 185 ASN ASN C . n 
C 1 207 CYS 207 186 186 CYS CYS C . n 
C 1 208 VAL 208 187 187 VAL VAL C . n 
C 1 209 VAL 209 188 188 VAL VAL C . n 
C 1 210 LEU 210 189 189 LEU LEU C . n 
C 1 211 LYS 211 190 190 LYS LYS C . n 
C 1 212 PRO 212 191 191 PRO PRO C . n 
C 1 213 ALA 213 192 192 ALA ALA C . n 
C 1 214 GLU 214 193 193 GLU GLU C . n 
C 1 215 GLN 215 194 194 GLN GLN C . n 
C 1 216 THR 216 195 195 THR THR C . n 
C 1 217 PRO 217 196 196 PRO PRO C . n 
C 1 218 ALA 218 197 197 ALA ALA C . n 
C 1 219 GLY 219 198 198 GLY GLY C . n 
C 1 220 ILE 220 199 199 ILE ILE C . n 
C 1 221 MET 221 200 200 MET MET C . n 
C 1 222 VAL 222 201 201 VAL VAL C . n 
C 1 223 TRP 223 202 202 TRP TRP C . n 
C 1 224 ALA 224 203 203 ALA ALA C . n 
C 1 225 ASN 225 204 204 ASN ASN C . n 
C 1 226 LEU 226 205 205 LEU LEU C . n 
C 1 227 ILE 227 206 206 ILE ILE C . n 
C 1 228 GLY 228 207 207 GLY GLY C . n 
C 1 229 ASP 229 208 208 ASP ASP C . n 
C 1 230 LEU 230 209 209 LEU LEU C . n 
C 1 231 LEU 231 210 210 LEU LEU C . n 
C 1 232 PRO 232 211 211 PRO PRO C . n 
C 1 233 PRO 233 212 212 PRO PRO C . n 
C 1 234 GLY 234 213 213 GLY GLY C . n 
C 1 235 VAL 235 214 214 VAL VAL C . n 
C 1 236 LEU 236 215 215 LEU LEU C . n 
C 1 237 ASN 237 216 216 ASN ASN C . n 
C 1 238 ILE 238 217 217 ILE ILE C . n 
C 1 239 VAL 239 218 218 VAL VAL C . n 
C 1 240 ASN 240 219 219 ASN ASN C . n 
C 1 241 GLY 241 220 220 GLY GLY C . n 
C 1 242 PHE 242 221 221 PHE PHE C . n 
C 1 243 GLY 243 222 222 GLY GLY C . n 
C 1 244 LEU 244 223 223 LEU LEU C . n 
C 1 245 GLU 245 224 224 GLU GLU C . n 
C 1 246 ALA 246 225 225 ALA ALA C . n 
C 1 247 GLY 247 226 226 GLY GLY C . n 
C 1 248 LYS 248 227 227 LYS LYS C . n 
C 1 249 PRO 249 228 228 PRO PRO C . n 
C 1 250 LEU 250 229 229 LEU LEU C . n 
C 1 251 ALA 251 230 230 ALA ALA C . n 
C 1 252 SER 252 231 231 SER SER C . n 
C 1 253 SER 253 232 232 SER SER C . n 
C 1 254 ASN 254 233 233 ASN ASN C . n 
C 1 255 ARG 255 234 234 ARG ARG C . n 
C 1 256 ILE 256 235 235 ILE ILE C . n 
C 1 257 ALA 257 236 236 ALA ALA C . n 
C 1 258 LYS 258 237 237 LYS LYS C . n 
C 1 259 ILE 259 238 238 ILE ILE C . n 
C 1 260 ALA 260 239 ?   ?   ?   C . n 
C 1 261 PHE 261 240 ?   ?   ?   C . n 
C 1 262 THR 262 241 ?   ?   ?   C . n 
C 1 263 GLY 263 242 ?   ?   ?   C . n 
C 1 264 GLU 264 243 ?   ?   ?   C . n 
C 1 265 THR 265 244 ?   ?   ?   C . n 
C 1 266 THR 266 245 ?   ?   ?   C . n 
C 1 267 THR 267 246 ?   ?   ?   C . n 
C 1 268 GLY 268 247 ?   ?   ?   C . n 
C 1 269 ARG 269 248 ?   ?   ?   C . n 
C 1 270 LEU 270 249 ?   ?   ?   C . n 
C 1 271 ILE 271 250 ?   ?   ?   C . n 
C 1 272 MET 272 251 ?   ?   ?   C . n 
C 1 273 GLN 273 252 ?   ?   ?   C . n 
C 1 274 TYR 274 253 ?   ?   ?   C . n 
C 1 275 ALA 275 254 ?   ?   ?   C . n 
C 1 276 SER 276 255 ?   ?   ?   C . n 
C 1 277 GLU 277 256 ?   ?   ?   C . n 
C 1 278 ASN 278 257 ?   ?   ?   C . n 
C 1 279 LEU 279 258 ?   ?   ?   C . n 
C 1 280 ILE 280 259 ?   ?   ?   C . n 
C 1 281 PRO 281 260 ?   ?   ?   C . n 
C 1 282 VAL 282 261 ?   ?   ?   C . n 
C 1 283 THR 283 262 ?   ?   ?   C . n 
C 1 284 LEU 284 263 ?   ?   ?   C . n 
C 1 285 GLU 285 264 ?   ?   ?   C . n 
C 1 286 LEU 286 265 ?   ?   ?   C . n 
C 1 287 GLY 287 266 266 GLY GLY C . n 
C 1 288 GLY 288 267 267 GLY GLY C . n 
C 1 289 LYS 289 268 268 LYS LYS C . n 
C 1 290 SER 290 269 269 SER SER C . n 
C 1 291 PRO 291 270 270 PRO PRO C . n 
C 1 292 ASN 292 271 271 ASN ASN C . n 
C 1 293 ILE 293 272 272 ILE ILE C . n 
C 1 294 PHE 294 273 273 PHE PHE C . n 
C 1 295 PHE 295 274 274 PHE PHE C . n 
C 1 296 ALA 296 275 275 ALA ALA C . n 
C 1 297 ASP 297 276 276 ASP ASP C . n 
C 1 298 VAL 298 277 277 VAL VAL C . n 
C 1 299 ALA 299 278 278 ALA ALA C . n 
C 1 300 ARG 300 279 279 ARG ARG C . n 
C 1 301 GLU 301 280 280 GLU GLU C . n 
C 1 302 ASP 302 281 281 ASP ASP C . n 
C 1 303 ASP 303 282 282 ASP ASP C . n 
C 1 304 ASP 304 283 283 ASP ASP C . n 
C 1 305 PHE 305 284 284 PHE PHE C . n 
C 1 306 PHE 306 285 285 PHE PHE C . n 
C 1 307 ASP 307 286 286 ASP ASP C . n 
C 1 308 LYS 308 287 287 LYS LYS C . n 
C 1 309 ALA 309 288 288 ALA ALA C . n 
C 1 310 LEU 310 289 289 LEU LEU C . n 
C 1 311 GLU 311 290 290 GLU GLU C . n 
C 1 312 GLY 312 291 291 GLY GLY C . n 
C 1 313 PHE 313 292 292 PHE PHE C . n 
C 1 314 THR 314 293 293 THR THR C . n 
C 1 315 MET 315 294 294 MET MET C . n 
C 1 316 PHE 316 295 295 PHE PHE C . n 
C 1 317 ALA 317 296 296 ALA ALA C . n 
C 1 318 LEU 318 297 297 LEU LEU C . n 
C 1 319 ASN 319 298 298 ASN ASN C . n 
C 1 320 GLN 320 299 299 GLN GLN C . n 
C 1 321 GLY 321 300 300 GLY GLY C . n 
C 1 322 GLU 322 301 301 GLU GLU C . n 
C 1 323 VAL 323 302 302 VAL VAL C . n 
C 1 324 CYS 324 303 303 CYS CYS C . n 
C 1 325 THR 325 304 304 THR THR C . n 
C 1 326 CYS 326 305 305 CYS CYS C . n 
C 1 327 PRO 327 306 306 PRO PRO C . n 
C 1 328 SER 328 307 307 SER SER C . n 
C 1 329 ARG 329 308 308 ARG ARG C . n 
C 1 330 VAL 330 309 309 VAL VAL C . n 
C 1 331 LEU 331 310 310 LEU LEU C . n 
C 1 332 ILE 332 311 311 ILE ILE C . n 
C 1 333 GLN 333 312 312 GLN GLN C . n 
C 1 334 GLU 334 313 313 GLU GLU C . n 
C 1 335 SER 335 314 314 SER SER C . n 
C 1 336 ILE 336 315 315 ILE ILE C . n 
C 1 337 TYR 337 316 316 TYR TYR C . n 
C 1 338 ASP 338 317 317 ASP ASP C . n 
C 1 339 LYS 339 318 318 LYS LYS C . n 
C 1 340 PHE 340 319 319 PHE PHE C . n 
C 1 341 MET 341 320 320 MET MET C . n 
C 1 342 GLU 342 321 321 GLU GLU C . n 
C 1 343 ARG 343 322 322 ARG ARG C . n 
C 1 344 ALA 344 323 323 ALA ALA C . n 
C 1 345 VAL 345 324 324 VAL VAL C . n 
C 1 346 GLN 346 325 325 GLN GLN C . n 
C 1 347 ARG 347 326 326 ARG ARG C . n 
C 1 348 VAL 348 327 327 VAL VAL C . n 
C 1 349 GLN 349 328 328 GLN GLN C . n 
C 1 350 ALA 350 329 329 ALA ALA C . n 
C 1 351 ILE 351 330 330 ILE ILE C . n 
C 1 352 LYS 352 331 331 LYS LYS C . n 
C 1 353 GLN 353 332 332 GLN GLN C . n 
C 1 354 GLY 354 333 333 GLY GLY C . n 
C 1 355 ASP 355 334 334 ASP ASP C . n 
C 1 356 PRO 356 335 335 PRO PRO C . n 
C 1 357 ARG 357 336 336 ARG ARG C . n 
C 1 358 GLU 358 337 337 GLU GLU C . n 
C 1 359 SER 359 338 338 SER SER C . n 
C 1 360 ASP 360 339 339 ASP ASP C . n 
C 1 361 THR 361 340 340 THR THR C . n 
C 1 362 MET 362 341 341 MET MET C . n 
C 1 363 ILE 363 342 342 ILE ILE C . n 
C 1 364 GLY 364 343 343 GLY GLY C . n 
C 1 365 ALA 365 344 344 ALA ALA C . n 
C 1 366 GLN 366 345 345 GLN GLN C . n 
C 1 367 ALA 367 346 346 ALA ALA C . n 
C 1 368 SER 368 347 347 SER SER C . n 
C 1 369 SER 369 348 348 SER SER C . n 
C 1 370 GLU 370 349 349 GLU GLU C . n 
C 1 371 GLN 371 350 350 GLN GLN C . n 
C 1 372 LYS 372 351 351 LYS LYS C . n 
C 1 373 GLU 373 352 352 GLU GLU C . n 
C 1 374 LYS 374 353 353 LYS LYS C . n 
C 1 375 ILE 375 354 354 ILE ILE C . n 
C 1 376 LEU 376 355 355 LEU LEU C . n 
C 1 377 SER 377 356 356 SER SER C . n 
C 1 378 TYR 378 357 357 TYR TYR C . n 
C 1 379 LEU 379 358 358 LEU LEU C . n 
C 1 380 ASP 380 359 359 ASP ASP C . n 
C 1 381 ILE 381 360 360 ILE ILE C . n 
C 1 382 GLY 382 361 361 GLY GLY C . n 
C 1 383 LYS 383 362 362 LYS LYS C . n 
C 1 384 LYS 384 363 363 LYS LYS C . n 
C 1 385 GLU 385 364 364 GLU GLU C . n 
C 1 386 GLY 386 365 365 GLY GLY C . n 
C 1 387 ALA 387 366 366 ALA ALA C . n 
C 1 388 GLU 388 367 367 GLU GLU C . n 
C 1 389 VAL 389 368 368 VAL VAL C . n 
C 1 390 LEU 390 369 369 LEU LEU C . n 
C 1 391 THR 391 370 370 THR THR C . n 
C 1 392 GLY 392 371 371 GLY GLY C . n 
C 1 393 GLY 393 372 372 GLY GLY C . n 
C 1 394 LYS 394 373 373 LYS LYS C . n 
C 1 395 ALA 395 374 374 ALA ALA C . n 
C 1 396 ALA 396 375 375 ALA ALA C . n 
C 1 397 ASP 397 376 376 ASP ASP C . n 
C 1 398 LEU 398 377 377 LEU LEU C . n 
C 1 399 GLY 399 378 378 GLY GLY C . n 
C 1 400 GLY 400 379 379 GLY GLY C . n 
C 1 401 GLU 401 380 380 GLU GLU C . n 
C 1 402 LEU 402 381 381 LEU LEU C . n 
C 1 403 SER 403 382 382 SER SER C . n 
C 1 404 GLY 404 383 383 GLY GLY C . n 
C 1 405 GLY 405 384 384 GLY GLY C . n 
C 1 406 TYR 406 385 385 TYR TYR C . n 
C 1 407 TYR 407 386 386 TYR TYR C . n 
C 1 408 ILE 408 387 387 ILE ILE C . n 
C 1 409 GLU 409 388 388 GLU GLU C . n 
C 1 410 PRO 410 389 389 PRO PRO C . n 
C 1 411 THR 411 390 390 THR THR C . n 
C 1 412 ILE 412 391 391 ILE ILE C . n 
C 1 413 PHE 413 392 392 PHE PHE C . n 
C 1 414 ARG 414 393 393 ARG ARG C . n 
C 1 415 GLY 415 394 394 GLY GLY C . n 
C 1 416 ASN 416 395 395 ASN ASN C . n 
C 1 417 ASN 417 396 396 ASN ASN C . n 
C 1 418 LYS 418 397 397 LYS LYS C . n 
C 1 419 MET 419 398 398 MET MET C . n 
C 1 420 ARG 420 399 399 ARG ARG C . n 
C 1 421 ILE 421 400 400 ILE ILE C . n 
C 1 422 PHE 422 401 401 PHE PHE C . n 
C 1 423 GLN 423 402 402 GLN GLN C . n 
C 1 424 GLU 424 403 403 GLU GLU C . n 
C 1 425 GLU 425 404 404 GLU GLU C . n 
C 1 426 ILE 426 405 405 ILE ILE C . n 
C 1 427 PHE 427 406 406 PHE PHE C . n 
C 1 428 GLY 428 407 407 GLY GLY C . n 
C 1 429 PRO 429 408 408 PRO PRO C . n 
C 1 430 VAL 430 409 409 VAL VAL C . n 
C 1 431 VAL 431 410 410 VAL VAL C . n 
C 1 432 SER 432 411 411 SER SER C . n 
C 1 433 VAL 433 412 412 VAL VAL C . n 
C 1 434 THR 434 413 413 THR THR C . n 
C 1 435 THR 435 414 414 THR THR C . n 
C 1 436 PHE 436 415 415 PHE PHE C . n 
C 1 437 LYS 437 416 416 LYS LYS C . n 
C 1 438 ASP 438 417 417 ASP ASP C . n 
C 1 439 GLN 439 418 418 GLN GLN C . n 
C 1 440 ALA 440 419 419 ALA ALA C . n 
C 1 441 GLU 441 420 420 GLU GLU C . n 
C 1 442 ALA 442 421 421 ALA ALA C . n 
C 1 443 LEU 443 422 422 LEU LEU C . n 
C 1 444 GLU 444 423 423 GLU GLU C . n 
C 1 445 ILE 445 424 424 ILE ILE C . n 
C 1 446 ALA 446 425 425 ALA ALA C . n 
C 1 447 ASN 447 426 426 ASN ASN C . n 
C 1 448 ASP 448 427 427 ASP ASP C . n 
C 1 449 THR 449 428 428 THR THR C . n 
C 1 450 LEU 450 429 429 LEU LEU C . n 
C 1 451 TYR 451 430 430 TYR TYR C . n 
C 1 452 GLY 452 431 431 GLY GLY C . n 
C 1 453 LEU 453 432 432 LEU LEU C . n 
C 1 454 GLY 454 433 433 GLY GLY C . n 
C 1 455 ALA 455 434 434 ALA ALA C . n 
C 1 456 GLY 456 435 435 GLY GLY C . n 
C 1 457 VAL 457 436 436 VAL VAL C . n 
C 1 458 TRP 458 437 437 TRP TRP C . n 
C 1 459 SER 459 438 438 SER SER C . n 
C 1 460 ARG 460 439 439 ARG ARG C . n 
C 1 461 ASP 461 440 440 ASP ASP C . n 
C 1 462 ALA 462 441 441 ALA ALA C . n 
C 1 463 ASN 463 442 442 ASN ASN C . n 
C 1 464 THR 464 443 443 THR THR C . n 
C 1 465 CYS 465 444 444 CYS CYS C . n 
C 1 466 TYR 466 445 445 TYR TYR C . n 
C 1 467 ARG 467 446 446 ARG ARG C . n 
C 1 468 MET 468 447 447 MET MET C . n 
C 1 469 GLY 469 448 448 GLY GLY C . n 
C 1 470 ARG 470 449 449 ARG ARG C . n 
C 1 471 GLY 471 450 450 GLY GLY C . n 
C 1 472 ILE 472 451 451 ILE ILE C . n 
C 1 473 LYS 473 452 452 LYS LYS C . n 
C 1 474 ALA 474 453 453 ALA ALA C . n 
C 1 475 GLY 475 454 454 GLY GLY C . n 
C 1 476 ARG 476 455 455 ARG ARG C . n 
C 1 477 VAL 477 456 456 VAL VAL C . n 
C 1 478 TRP 478 457 457 TRP TRP C . n 
C 1 479 THR 479 458 458 THR THR C . n 
C 1 480 ASN 480 459 459 ASN ASN C . n 
C 1 481 CYS 481 460 460 CYS CYS C . n 
C 1 482 TYR 482 461 461 TYR TYR C . n 
C 1 483 HIS 483 462 462 HIS HIS C . n 
C 1 484 ALA 484 463 463 ALA ALA C . n 
C 1 485 TYR 485 464 464 TYR TYR C . n 
C 1 486 PRO 486 465 465 PRO PRO C . n 
C 1 487 ALA 487 466 466 ALA ALA C . n 
C 1 488 HIS 488 467 467 HIS HIS C . n 
C 1 489 ALA 489 468 468 ALA ALA C . n 
C 1 490 ALA 490 469 469 ALA ALA C . n 
C 1 491 PHE 491 470 ?   ?   ?   C . n 
C 1 492 GLY 492 471 ?   ?   ?   C . n 
C 1 493 GLY 493 472 ?   ?   ?   C . n 
C 1 494 TYR 494 473 ?   ?   ?   C . n 
C 1 495 LYS 495 474 ?   ?   ?   C . n 
C 1 496 GLN 496 475 ?   ?   ?   C . n 
C 1 497 SER 497 476 ?   ?   ?   C . n 
C 1 498 GLY 498 477 ?   ?   ?   C . n 
C 1 499 ILE 499 478 ?   ?   ?   C . n 
C 1 500 GLY 500 479 ?   ?   ?   C . n 
C 1 501 ARG 501 480 ?   ?   ?   C . n 
C 1 502 GLU 502 481 ?   ?   ?   C . n 
C 1 503 THR 503 482 482 THR THR C . n 
C 1 504 HIS 504 483 483 HIS HIS C . n 
C 1 505 LYS 505 484 484 LYS LYS C . n 
C 1 506 MET 506 485 485 MET MET C . n 
C 1 507 MET 507 486 486 MET MET C . n 
C 1 508 LEU 508 487 487 LEU LEU C . n 
C 1 509 ASP 509 488 488 ASP ASP C . n 
C 1 510 HIS 510 489 489 HIS HIS C . n 
C 1 511 TYR 511 490 490 TYR TYR C . n 
C 1 512 GLN 512 491 491 GLN GLN C . n 
C 1 513 GLN 513 492 492 GLN GLN C . n 
C 1 514 THR 514 493 493 THR THR C . n 
C 1 515 LYS 515 494 494 LYS LYS C . n 
C 1 516 ASN 516 495 495 ASN ASN C . n 
C 1 517 MET 517 496 496 MET MET C . n 
C 1 518 LEU 518 497 497 LEU LEU C . n 
C 1 519 VAL 519 498 498 VAL VAL C . n 
C 1 520 SER 520 499 499 SER SER C . n 
C 1 521 TYR 521 500 500 TYR TYR C . n 
C 1 522 SER 522 501 501 SER SER C . n 
C 1 523 PRO 523 502 502 PRO PRO C . n 
C 1 524 LYS 524 503 503 LYS LYS C . n 
C 1 525 LYS 525 504 504 LYS LYS C . n 
C 1 526 LEU 526 505 ?   ?   ?   C . n 
C 1 527 GLY 527 506 ?   ?   ?   C . n 
C 1 528 PHE 528 507 ?   ?   ?   C . n 
C 1 529 PHE 529 508 ?   ?   ?   C . n 
D 1 1   MET 1   -20 ?   ?   ?   D . n 
D 1 2   GLY 2   -19 ?   ?   ?   D . n 
D 1 3   HIS 3   -18 ?   ?   ?   D . n 
D 1 4   HIS 4   -17 ?   ?   ?   D . n 
D 1 5   HIS 5   -16 ?   ?   ?   D . n 
D 1 6   HIS 6   -15 ?   ?   ?   D . n 
D 1 7   HIS 7   -14 ?   ?   ?   D . n 
D 1 8   HIS 8   -13 ?   ?   ?   D . n 
D 1 9   HIS 9   -12 ?   ?   ?   D . n 
D 1 10  HIS 10  -11 ?   ?   ?   D . n 
D 1 11  HIS 11  -10 ?   ?   ?   D . n 
D 1 12  HIS 12  -9  ?   ?   ?   D . n 
D 1 13  SER 13  -8  ?   ?   ?   D . n 
D 1 14  SER 14  -7  ?   ?   ?   D . n 
D 1 15  GLY 15  -6  ?   ?   ?   D . n 
D 1 16  HIS 16  -5  ?   ?   ?   D . n 
D 1 17  ILE 17  -4  ?   ?   ?   D . n 
D 1 18  GLU 18  -3  ?   ?   ?   D . n 
D 1 19  GLY 19  -2  ?   ?   ?   D . n 
D 1 20  ARG 20  -1  ?   ?   ?   D . n 
D 1 21  HIS 21  0   ?   ?   ?   D . n 
D 1 22  MET 22  1   ?   ?   ?   D . n 
D 1 23  PRO 23  2   ?   ?   ?   D . n 
D 1 24  ASN 24  3   ?   ?   ?   D . n 
D 1 25  ASP 25  4   ?   ?   ?   D . n 
D 1 26  GLN 26  5   ?   ?   ?   D . n 
D 1 27  THR 27  6   ?   ?   ?   D . n 
D 1 28  HIS 28  7   ?   ?   ?   D . n 
D 1 29  PRO 29  8   ?   ?   ?   D . n 
D 1 30  PHE 30  9   ?   ?   ?   D . n 
D 1 31  ARG 31  10  ?   ?   ?   D . n 
D 1 32  GLY 32  11  ?   ?   ?   D . n 
D 1 33  VAL 33  12  ?   ?   ?   D . n 
D 1 34  ASN 34  13  ?   ?   ?   D . n 
D 1 35  ALA 35  14  ?   ?   ?   D . n 
D 1 36  LEU 36  15  ?   ?   ?   D . n 
D 1 37  PRO 37  16  ?   ?   ?   D . n 
D 1 38  PHE 38  17  ?   ?   ?   D . n 
D 1 39  GLU 39  18  ?   ?   ?   D . n 
D 1 40  GLU 40  19  ?   ?   ?   D . n 
D 1 41  ARG 41  20  ?   ?   ?   D . n 
D 1 42  TYR 42  21  ?   ?   ?   D . n 
D 1 43  ASP 43  22  ?   ?   ?   D . n 
D 1 44  ASN 44  23  ?   ?   ?   D . n 
D 1 45  PHE 45  24  ?   ?   ?   D . n 
D 1 46  ILE 46  25  ?   ?   ?   D . n 
D 1 47  GLY 47  26  ?   ?   ?   D . n 
D 1 48  GLY 48  27  ?   ?   ?   D . n 
D 1 49  GLU 49  28  ?   ?   ?   D . n 
D 1 50  TRP 50  29  ?   ?   ?   D . n 
D 1 51  VAL 51  30  ?   ?   ?   D . n 
D 1 52  ALA 52  31  ?   ?   ?   D . n 
D 1 53  PRO 53  32  ?   ?   ?   D . n 
D 1 54  VAL 54  33  ?   ?   ?   D . n 
D 1 55  SER 55  34  ?   ?   ?   D . n 
D 1 56  GLY 56  35  ?   ?   ?   D . n 
D 1 57  ARG 57  36  ?   ?   ?   D . n 
D 1 58  TYR 58  37  ?   ?   ?   D . n 
D 1 59  PHE 59  38  ?   ?   ?   D . n 
D 1 60  THR 60  39  ?   ?   ?   D . n 
D 1 61  ASN 61  40  ?   ?   ?   D . n 
D 1 62  THR 62  41  ?   ?   ?   D . n 
D 1 63  THR 63  42  ?   ?   ?   D . n 
D 1 64  PRO 64  43  ?   ?   ?   D . n 
D 1 65  ILE 65  44  ?   ?   ?   D . n 
D 1 66  THR 66  45  ?   ?   ?   D . n 
D 1 67  GLY 67  46  ?   ?   ?   D . n 
D 1 68  ALA 68  47  ?   ?   ?   D . n 
D 1 69  GLU 69  48  ?   ?   ?   D . n 
D 1 70  ILE 70  49  ?   ?   ?   D . n 
D 1 71  GLY 71  50  ?   ?   ?   D . n 
D 1 72  GLN 72  51  ?   ?   ?   D . n 
D 1 73  ILE 73  52  ?   ?   ?   D . n 
D 1 74  ALA 74  53  ?   ?   ?   D . n 
D 1 75  ARG 75  54  ?   ?   ?   D . n 
D 1 76  SER 76  55  ?   ?   ?   D . n 
D 1 77  GLU 77  56  ?   ?   ?   D . n 
D 1 78  ALA 78  57  ?   ?   ?   D . n 
D 1 79  GLY 79  58  58  GLY GLY D . n 
D 1 80  ASP 80  59  59  ASP ASP D . n 
D 1 81  ILE 81  60  60  ILE ILE D . n 
D 1 82  GLU 82  61  61  GLU GLU D . n 
D 1 83  LEU 83  62  62  LEU LEU D . n 
D 1 84  ALA 84  63  63  ALA ALA D . n 
D 1 85  LEU 85  64  64  LEU LEU D . n 
D 1 86  ASP 86  65  65  ASP ASP D . n 
D 1 87  ALA 87  66  66  ALA ALA D . n 
D 1 88  ALA 88  67  67  ALA ALA D . n 
D 1 89  HIS 89  68  68  HIS HIS D . n 
D 1 90  ALA 90  69  69  ALA ALA D . n 
D 1 91  ALA 91  70  70  ALA ALA D . n 
D 1 92  LYS 92  71  71  LYS LYS D . n 
D 1 93  GLU 93  72  72  GLU GLU D . n 
D 1 94  LYS 94  73  73  LYS LYS D . n 
D 1 95  TRP 95  74  74  TRP TRP D . n 
D 1 96  GLY 96  75  75  GLY GLY D . n 
D 1 97  ALA 97  76  76  ALA ALA D . n 
D 1 98  THR 98  77  77  THR THR D . n 
D 1 99  SER 99  78  78  SER SER D . n 
D 1 100 PRO 100 79  79  PRO PRO D . n 
D 1 101 ALA 101 80  80  ALA ALA D . n 
D 1 102 GLU 102 81  81  GLU GLU D . n 
D 1 103 ARG 103 82  82  ARG ARG D . n 
D 1 104 ALA 104 83  83  ALA ALA D . n 
D 1 105 ASN 105 84  84  ASN ASN D . n 
D 1 106 ILE 106 85  85  ILE ILE D . n 
D 1 107 MET 107 86  86  MET MET D . n 
D 1 108 LEU 108 87  87  LEU LEU D . n 
D 1 109 LYS 109 88  88  LYS LYS D . n 
D 1 110 ILE 110 89  89  ILE ILE D . n 
D 1 111 ALA 111 90  90  ALA ALA D . n 
D 1 112 ASP 112 91  91  ASP ASP D . n 
D 1 113 ARG 113 92  92  ARG ARG D . n 
D 1 114 MET 114 93  93  MET MET D . n 
D 1 115 GLU 115 94  94  GLU GLU D . n 
D 1 116 ARG 116 95  95  ARG ARG D . n 
D 1 117 ASN 117 96  96  ASN ASN D . n 
D 1 118 LEU 118 97  97  LEU LEU D . n 
D 1 119 GLU 119 98  ?   ?   ?   D . n 
D 1 120 LEU 120 99  ?   ?   ?   D . n 
D 1 121 LEU 121 100 ?   ?   ?   D . n 
D 1 122 ALA 122 101 ?   ?   ?   D . n 
D 1 123 THR 123 102 ?   ?   ?   D . n 
D 1 124 ALA 124 103 ?   ?   ?   D . n 
D 1 125 GLU 125 104 ?   ?   ?   D . n 
D 1 126 THR 126 105 ?   ?   ?   D . n 
D 1 127 TRP 127 106 ?   ?   ?   D . n 
D 1 128 ASP 128 107 ?   ?   ?   D . n 
D 1 129 ASN 129 108 ?   ?   ?   D . n 
D 1 130 GLY 130 109 ?   ?   ?   D . n 
D 1 131 LYS 131 110 ?   ?   ?   D . n 
D 1 132 PRO 132 111 ?   ?   ?   D . n 
D 1 133 ILE 133 112 ?   ?   ?   D . n 
D 1 134 ARG 134 113 ?   ?   ?   D . n 
D 1 135 GLU 135 114 ?   ?   ?   D . n 
D 1 136 THR 136 115 ?   ?   ?   D . n 
D 1 137 MET 137 116 ?   ?   ?   D . n 
D 1 138 ALA 138 117 ?   ?   ?   D . n 
D 1 139 ALA 139 118 118 ALA ALA D . n 
D 1 140 ASP 140 119 119 ASP ASP D . n 
D 1 141 LEU 141 120 120 LEU LEU D . n 
D 1 142 PRO 142 121 121 PRO PRO D . n 
D 1 143 LEU 143 122 122 LEU LEU D . n 
D 1 144 ALA 144 123 123 ALA ALA D . n 
D 1 145 ILE 145 124 124 ILE ILE D . n 
D 1 146 ASP 146 125 125 ASP ASP D . n 
D 1 147 HIS 147 126 126 HIS HIS D . n 
D 1 148 PHE 148 127 127 PHE PHE D . n 
D 1 149 ARG 149 128 128 ARG ARG D . n 
D 1 150 TYR 150 129 129 TYR TYR D . n 
D 1 151 PHE 151 130 130 PHE PHE D . n 
D 1 152 ALA 152 131 131 ALA ALA D . n 
D 1 153 GLY 153 132 132 GLY GLY D . n 
D 1 154 VAL 154 133 133 VAL VAL D . n 
D 1 155 LEU 155 134 134 LEU LEU D . n 
D 1 156 ARG 156 135 135 ARG ARG D . n 
D 1 157 ALA 157 136 136 ALA ALA D . n 
D 1 158 GLN 158 137 137 GLN GLN D . n 
D 1 159 GLU 159 138 138 GLU GLU D . n 
D 1 160 GLY 160 139 139 GLY GLY D . n 
D 1 161 SER 161 140 140 SER SER D . n 
D 1 162 ILE 162 141 141 ILE ILE D . n 
D 1 163 SER 163 142 142 SER SER D . n 
D 1 164 GLN 164 143 143 GLN GLN D . n 
D 1 165 ILE 165 144 144 ILE ILE D . n 
D 1 166 ASP 166 145 145 ASP ASP D . n 
D 1 167 ASP 167 146 146 ASP ASP D . n 
D 1 168 ASP 168 147 147 ASP ASP D . n 
D 1 169 THR 169 148 148 THR THR D . n 
D 1 170 VAL 170 149 149 VAL VAL D . n 
D 1 171 ALA 171 150 150 ALA ALA D . n 
D 1 172 TYR 172 151 151 TYR TYR D . n 
D 1 173 HIS 173 152 152 HIS HIS D . n 
D 1 174 PHE 174 153 153 PHE PHE D . n 
D 1 175 HIS 175 154 154 HIS HIS D . n 
D 1 176 GLU 176 155 155 GLU GLU D . n 
D 1 177 PRO 177 156 156 PRO PRO D . n 
D 1 178 LEU 178 157 157 LEU LEU D . n 
D 1 179 GLY 179 158 158 GLY GLY D . n 
D 1 180 VAL 180 159 159 VAL VAL D . n 
D 1 181 VAL 181 160 160 VAL VAL D . n 
D 1 182 GLY 182 161 161 GLY GLY D . n 
D 1 183 GLN 183 162 162 GLN GLN D . n 
D 1 184 ILE 184 163 ?   ?   ?   D . n 
D 1 185 ILE 185 164 ?   ?   ?   D . n 
D 1 186 PRO 186 165 ?   ?   ?   D . n 
D 1 187 TRP 187 166 ?   ?   ?   D . n 
D 1 188 ASN 188 167 ?   ?   ?   D . n 
D 1 189 PHE 189 168 ?   ?   ?   D . n 
D 1 190 PRO 190 169 169 PRO PRO D . n 
D 1 191 LEU 191 170 170 LEU LEU D . n 
D 1 192 LEU 192 171 171 LEU LEU D . n 
D 1 193 MET 193 172 172 MET MET D . n 
D 1 194 ALA 194 173 173 ALA ALA D . n 
D 1 195 CYS 195 174 174 CYS CYS D . n 
D 1 196 TRP 196 175 175 TRP TRP D . n 
D 1 197 LYS 197 176 176 LYS LYS D . n 
D 1 198 LEU 198 177 177 LEU LEU D . n 
D 1 199 ALA 199 178 178 ALA ALA D . n 
D 1 200 PRO 200 179 179 PRO PRO D . n 
D 1 201 ALA 201 180 180 ALA ALA D . n 
D 1 202 ILE 202 181 181 ILE ILE D . n 
D 1 203 ALA 203 182 182 ALA ALA D . n 
D 1 204 ALA 204 183 183 ALA ALA D . n 
D 1 205 GLY 205 184 184 GLY GLY D . n 
D 1 206 ASN 206 185 185 ASN ASN D . n 
D 1 207 CYS 207 186 186 CYS CYS D . n 
D 1 208 VAL 208 187 187 VAL VAL D . n 
D 1 209 VAL 209 188 188 VAL VAL D . n 
D 1 210 LEU 210 189 189 LEU LEU D . n 
D 1 211 LYS 211 190 ?   ?   ?   D . n 
D 1 212 PRO 212 191 ?   ?   ?   D . n 
D 1 213 ALA 213 192 ?   ?   ?   D . n 
D 1 214 GLU 214 193 ?   ?   ?   D . n 
D 1 215 GLN 215 194 ?   ?   ?   D . n 
D 1 216 THR 216 195 ?   ?   ?   D . n 
D 1 217 PRO 217 196 ?   ?   ?   D . n 
D 1 218 ALA 218 197 ?   ?   ?   D . n 
D 1 219 GLY 219 198 ?   ?   ?   D . n 
D 1 220 ILE 220 199 199 ILE ILE D . n 
D 1 221 MET 221 200 200 MET MET D . n 
D 1 222 VAL 222 201 201 VAL VAL D . n 
D 1 223 TRP 223 202 202 TRP TRP D . n 
D 1 224 ALA 224 203 203 ALA ALA D . n 
D 1 225 ASN 225 204 204 ASN ASN D . n 
D 1 226 LEU 226 205 205 LEU LEU D . n 
D 1 227 ILE 227 206 206 ILE ILE D . n 
D 1 228 GLY 228 207 207 GLY GLY D . n 
D 1 229 ASP 229 208 208 ASP ASP D . n 
D 1 230 LEU 230 209 209 LEU LEU D . n 
D 1 231 LEU 231 210 210 LEU LEU D . n 
D 1 232 PRO 232 211 211 PRO PRO D . n 
D 1 233 PRO 233 212 212 PRO PRO D . n 
D 1 234 GLY 234 213 213 GLY GLY D . n 
D 1 235 VAL 235 214 214 VAL VAL D . n 
D 1 236 LEU 236 215 215 LEU LEU D . n 
D 1 237 ASN 237 216 216 ASN ASN D . n 
D 1 238 ILE 238 217 ?   ?   ?   D . n 
D 1 239 VAL 239 218 ?   ?   ?   D . n 
D 1 240 ASN 240 219 ?   ?   ?   D . n 
D 1 241 GLY 241 220 ?   ?   ?   D . n 
D 1 242 PHE 242 221 ?   ?   ?   D . n 
D 1 243 GLY 243 222 ?   ?   ?   D . n 
D 1 244 LEU 244 223 ?   ?   ?   D . n 
D 1 245 GLU 245 224 ?   ?   ?   D . n 
D 1 246 ALA 246 225 ?   ?   ?   D . n 
D 1 247 GLY 247 226 ?   ?   ?   D . n 
D 1 248 LYS 248 227 ?   ?   ?   D . n 
D 1 249 PRO 249 228 ?   ?   ?   D . n 
D 1 250 LEU 250 229 ?   ?   ?   D . n 
D 1 251 ALA 251 230 ?   ?   ?   D . n 
D 1 252 SER 252 231 ?   ?   ?   D . n 
D 1 253 SER 253 232 ?   ?   ?   D . n 
D 1 254 ASN 254 233 ?   ?   ?   D . n 
D 1 255 ARG 255 234 ?   ?   ?   D . n 
D 1 256 ILE 256 235 ?   ?   ?   D . n 
D 1 257 ALA 257 236 ?   ?   ?   D . n 
D 1 258 LYS 258 237 ?   ?   ?   D . n 
D 1 259 ILE 259 238 ?   ?   ?   D . n 
D 1 260 ALA 260 239 ?   ?   ?   D . n 
D 1 261 PHE 261 240 ?   ?   ?   D . n 
D 1 262 THR 262 241 ?   ?   ?   D . n 
D 1 263 GLY 263 242 ?   ?   ?   D . n 
D 1 264 GLU 264 243 ?   ?   ?   D . n 
D 1 265 THR 265 244 ?   ?   ?   D . n 
D 1 266 THR 266 245 ?   ?   ?   D . n 
D 1 267 THR 267 246 ?   ?   ?   D . n 
D 1 268 GLY 268 247 ?   ?   ?   D . n 
D 1 269 ARG 269 248 ?   ?   ?   D . n 
D 1 270 LEU 270 249 ?   ?   ?   D . n 
D 1 271 ILE 271 250 ?   ?   ?   D . n 
D 1 272 MET 272 251 ?   ?   ?   D . n 
D 1 273 GLN 273 252 ?   ?   ?   D . n 
D 1 274 TYR 274 253 ?   ?   ?   D . n 
D 1 275 ALA 275 254 ?   ?   ?   D . n 
D 1 276 SER 276 255 ?   ?   ?   D . n 
D 1 277 GLU 277 256 ?   ?   ?   D . n 
D 1 278 ASN 278 257 ?   ?   ?   D . n 
D 1 279 LEU 279 258 ?   ?   ?   D . n 
D 1 280 ILE 280 259 ?   ?   ?   D . n 
D 1 281 PRO 281 260 ?   ?   ?   D . n 
D 1 282 VAL 282 261 ?   ?   ?   D . n 
D 1 283 THR 283 262 ?   ?   ?   D . n 
D 1 284 LEU 284 263 ?   ?   ?   D . n 
D 1 285 GLU 285 264 ?   ?   ?   D . n 
D 1 286 LEU 286 265 ?   ?   ?   D . n 
D 1 287 GLY 287 266 ?   ?   ?   D . n 
D 1 288 GLY 288 267 ?   ?   ?   D . n 
D 1 289 LYS 289 268 ?   ?   ?   D . n 
D 1 290 SER 290 269 269 SER SER D . n 
D 1 291 PRO 291 270 270 PRO PRO D . n 
D 1 292 ASN 292 271 271 ASN ASN D . n 
D 1 293 ILE 293 272 272 ILE ILE D . n 
D 1 294 PHE 294 273 273 PHE PHE D . n 
D 1 295 PHE 295 274 274 PHE PHE D . n 
D 1 296 ALA 296 275 275 ALA ALA D . n 
D 1 297 ASP 297 276 276 ASP ASP D . n 
D 1 298 VAL 298 277 ?   ?   ?   D . n 
D 1 299 ALA 299 278 ?   ?   ?   D . n 
D 1 300 ARG 300 279 ?   ?   ?   D . n 
D 1 301 GLU 301 280 ?   ?   ?   D . n 
D 1 302 ASP 302 281 ?   ?   ?   D . n 
D 1 303 ASP 303 282 ?   ?   ?   D . n 
D 1 304 ASP 304 283 ?   ?   ?   D . n 
D 1 305 PHE 305 284 ?   ?   ?   D . n 
D 1 306 PHE 306 285 ?   ?   ?   D . n 
D 1 307 ASP 307 286 ?   ?   ?   D . n 
D 1 308 LYS 308 287 ?   ?   ?   D . n 
D 1 309 ALA 309 288 ?   ?   ?   D . n 
D 1 310 LEU 310 289 ?   ?   ?   D . n 
D 1 311 GLU 311 290 ?   ?   ?   D . n 
D 1 312 GLY 312 291 ?   ?   ?   D . n 
D 1 313 PHE 313 292 ?   ?   ?   D . n 
D 1 314 THR 314 293 ?   ?   ?   D . n 
D 1 315 MET 315 294 ?   ?   ?   D . n 
D 1 316 PHE 316 295 ?   ?   ?   D . n 
D 1 317 ALA 317 296 ?   ?   ?   D . n 
D 1 318 LEU 318 297 ?   ?   ?   D . n 
D 1 319 ASN 319 298 ?   ?   ?   D . n 
D 1 320 GLN 320 299 ?   ?   ?   D . n 
D 1 321 GLY 321 300 ?   ?   ?   D . n 
D 1 322 GLU 322 301 ?   ?   ?   D . n 
D 1 323 VAL 323 302 ?   ?   ?   D . n 
D 1 324 CYS 324 303 ?   ?   ?   D . n 
D 1 325 THR 325 304 ?   ?   ?   D . n 
D 1 326 CYS 326 305 ?   ?   ?   D . n 
D 1 327 PRO 327 306 ?   ?   ?   D . n 
D 1 328 SER 328 307 ?   ?   ?   D . n 
D 1 329 ARG 329 308 308 ARG ARG D . n 
D 1 330 VAL 330 309 309 VAL VAL D . n 
D 1 331 LEU 331 310 310 LEU LEU D . n 
D 1 332 ILE 332 311 311 ILE ILE D . n 
D 1 333 GLN 333 312 312 GLN GLN D . n 
D 1 334 GLU 334 313 ?   ?   ?   D . n 
D 1 335 SER 335 314 ?   ?   ?   D . n 
D 1 336 ILE 336 315 ?   ?   ?   D . n 
D 1 337 TYR 337 316 ?   ?   ?   D . n 
D 1 338 ASP 338 317 ?   ?   ?   D . n 
D 1 339 LYS 339 318 ?   ?   ?   D . n 
D 1 340 PHE 340 319 ?   ?   ?   D . n 
D 1 341 MET 341 320 ?   ?   ?   D . n 
D 1 342 GLU 342 321 ?   ?   ?   D . n 
D 1 343 ARG 343 322 ?   ?   ?   D . n 
D 1 344 ALA 344 323 ?   ?   ?   D . n 
D 1 345 VAL 345 324 ?   ?   ?   D . n 
D 1 346 GLN 346 325 ?   ?   ?   D . n 
D 1 347 ARG 347 326 ?   ?   ?   D . n 
D 1 348 VAL 348 327 ?   ?   ?   D . n 
D 1 349 GLN 349 328 ?   ?   ?   D . n 
D 1 350 ALA 350 329 ?   ?   ?   D . n 
D 1 351 ILE 351 330 ?   ?   ?   D . n 
D 1 352 LYS 352 331 ?   ?   ?   D . n 
D 1 353 GLN 353 332 ?   ?   ?   D . n 
D 1 354 GLY 354 333 ?   ?   ?   D . n 
D 1 355 ASP 355 334 ?   ?   ?   D . n 
D 1 356 PRO 356 335 ?   ?   ?   D . n 
D 1 357 ARG 357 336 ?   ?   ?   D . n 
D 1 358 GLU 358 337 ?   ?   ?   D . n 
D 1 359 SER 359 338 ?   ?   ?   D . n 
D 1 360 ASP 360 339 ?   ?   ?   D . n 
D 1 361 THR 361 340 ?   ?   ?   D . n 
D 1 362 MET 362 341 ?   ?   ?   D . n 
D 1 363 ILE 363 342 ?   ?   ?   D . n 
D 1 364 GLY 364 343 ?   ?   ?   D . n 
D 1 365 ALA 365 344 ?   ?   ?   D . n 
D 1 366 GLN 366 345 ?   ?   ?   D . n 
D 1 367 ALA 367 346 ?   ?   ?   D . n 
D 1 368 SER 368 347 ?   ?   ?   D . n 
D 1 369 SER 369 348 ?   ?   ?   D . n 
D 1 370 GLU 370 349 ?   ?   ?   D . n 
D 1 371 GLN 371 350 ?   ?   ?   D . n 
D 1 372 LYS 372 351 ?   ?   ?   D . n 
D 1 373 GLU 373 352 ?   ?   ?   D . n 
D 1 374 LYS 374 353 ?   ?   ?   D . n 
D 1 375 ILE 375 354 ?   ?   ?   D . n 
D 1 376 LEU 376 355 ?   ?   ?   D . n 
D 1 377 SER 377 356 ?   ?   ?   D . n 
D 1 378 TYR 378 357 ?   ?   ?   D . n 
D 1 379 LEU 379 358 ?   ?   ?   D . n 
D 1 380 ASP 380 359 ?   ?   ?   D . n 
D 1 381 ILE 381 360 ?   ?   ?   D . n 
D 1 382 GLY 382 361 ?   ?   ?   D . n 
D 1 383 LYS 383 362 ?   ?   ?   D . n 
D 1 384 LYS 384 363 ?   ?   ?   D . n 
D 1 385 GLU 385 364 ?   ?   ?   D . n 
D 1 386 GLY 386 365 ?   ?   ?   D . n 
D 1 387 ALA 387 366 ?   ?   ?   D . n 
D 1 388 GLU 388 367 ?   ?   ?   D . n 
D 1 389 VAL 389 368 ?   ?   ?   D . n 
D 1 390 LEU 390 369 ?   ?   ?   D . n 
D 1 391 THR 391 370 ?   ?   ?   D . n 
D 1 392 GLY 392 371 ?   ?   ?   D . n 
D 1 393 GLY 393 372 ?   ?   ?   D . n 
D 1 394 LYS 394 373 ?   ?   ?   D . n 
D 1 395 ALA 395 374 ?   ?   ?   D . n 
D 1 396 ALA 396 375 ?   ?   ?   D . n 
D 1 397 ASP 397 376 ?   ?   ?   D . n 
D 1 398 LEU 398 377 ?   ?   ?   D . n 
D 1 399 GLY 399 378 ?   ?   ?   D . n 
D 1 400 GLY 400 379 ?   ?   ?   D . n 
D 1 401 GLU 401 380 ?   ?   ?   D . n 
D 1 402 LEU 402 381 ?   ?   ?   D . n 
D 1 403 SER 403 382 ?   ?   ?   D . n 
D 1 404 GLY 404 383 ?   ?   ?   D . n 
D 1 405 GLY 405 384 ?   ?   ?   D . n 
D 1 406 TYR 406 385 ?   ?   ?   D . n 
D 1 407 TYR 407 386 ?   ?   ?   D . n 
D 1 408 ILE 408 387 ?   ?   ?   D . n 
D 1 409 GLU 409 388 ?   ?   ?   D . n 
D 1 410 PRO 410 389 ?   ?   ?   D . n 
D 1 411 THR 411 390 ?   ?   ?   D . n 
D 1 412 ILE 412 391 ?   ?   ?   D . n 
D 1 413 PHE 413 392 ?   ?   ?   D . n 
D 1 414 ARG 414 393 ?   ?   ?   D . n 
D 1 415 GLY 415 394 ?   ?   ?   D . n 
D 1 416 ASN 416 395 ?   ?   ?   D . n 
D 1 417 ASN 417 396 ?   ?   ?   D . n 
D 1 418 LYS 418 397 ?   ?   ?   D . n 
D 1 419 MET 419 398 ?   ?   ?   D . n 
D 1 420 ARG 420 399 ?   ?   ?   D . n 
D 1 421 ILE 421 400 ?   ?   ?   D . n 
D 1 422 PHE 422 401 ?   ?   ?   D . n 
D 1 423 GLN 423 402 ?   ?   ?   D . n 
D 1 424 GLU 424 403 ?   ?   ?   D . n 
D 1 425 GLU 425 404 ?   ?   ?   D . n 
D 1 426 ILE 426 405 ?   ?   ?   D . n 
D 1 427 PHE 427 406 ?   ?   ?   D . n 
D 1 428 GLY 428 407 ?   ?   ?   D . n 
D 1 429 PRO 429 408 ?   ?   ?   D . n 
D 1 430 VAL 430 409 ?   ?   ?   D . n 
D 1 431 VAL 431 410 ?   ?   ?   D . n 
D 1 432 SER 432 411 ?   ?   ?   D . n 
D 1 433 VAL 433 412 412 VAL VAL D . n 
D 1 434 THR 434 413 413 THR THR D . n 
D 1 435 THR 435 414 414 THR THR D . n 
D 1 436 PHE 436 415 415 PHE PHE D . n 
D 1 437 LYS 437 416 416 LYS LYS D . n 
D 1 438 ASP 438 417 417 ASP ASP D . n 
D 1 439 GLN 439 418 418 GLN GLN D . n 
D 1 440 ALA 440 419 419 ALA ALA D . n 
D 1 441 GLU 441 420 420 GLU GLU D . n 
D 1 442 ALA 442 421 421 ALA ALA D . n 
D 1 443 LEU 443 422 422 LEU LEU D . n 
D 1 444 GLU 444 423 423 GLU GLU D . n 
D 1 445 ILE 445 424 424 ILE ILE D . n 
D 1 446 ALA 446 425 425 ALA ALA D . n 
D 1 447 ASN 447 426 ?   ?   ?   D . n 
D 1 448 ASP 448 427 ?   ?   ?   D . n 
D 1 449 THR 449 428 ?   ?   ?   D . n 
D 1 450 LEU 450 429 ?   ?   ?   D . n 
D 1 451 TYR 451 430 ?   ?   ?   D . n 
D 1 452 GLY 452 431 ?   ?   ?   D . n 
D 1 453 LEU 453 432 ?   ?   ?   D . n 
D 1 454 GLY 454 433 433 GLY GLY D . n 
D 1 455 ALA 455 434 434 ALA ALA D . n 
D 1 456 GLY 456 435 435 GLY GLY D . n 
D 1 457 VAL 457 436 436 VAL VAL D . n 
D 1 458 TRP 458 437 437 TRP TRP D . n 
D 1 459 SER 459 438 438 SER SER D . n 
D 1 460 ARG 460 439 439 ARG ARG D . n 
D 1 461 ASP 461 440 440 ASP ASP D . n 
D 1 462 ALA 462 441 441 ALA ALA D . n 
D 1 463 ASN 463 442 442 ASN ASN D . n 
D 1 464 THR 464 443 443 THR THR D . n 
D 1 465 CYS 465 444 444 CYS CYS D . n 
D 1 466 TYR 466 445 445 TYR TYR D . n 
D 1 467 ARG 467 446 446 ARG ARG D . n 
D 1 468 MET 468 447 447 MET MET D . n 
D 1 469 GLY 469 448 448 GLY GLY D . n 
D 1 470 ARG 470 449 449 ARG ARG D . n 
D 1 471 GLY 471 450 450 GLY GLY D . n 
D 1 472 ILE 472 451 451 ILE ILE D . n 
D 1 473 LYS 473 452 452 LYS LYS D . n 
D 1 474 ALA 474 453 453 ALA ALA D . n 
D 1 475 GLY 475 454 454 GLY GLY D . n 
D 1 476 ARG 476 455 455 ARG ARG D . n 
D 1 477 VAL 477 456 456 VAL VAL D . n 
D 1 478 TRP 478 457 457 TRP TRP D . n 
D 1 479 THR 479 458 458 THR THR D . n 
D 1 480 ASN 480 459 459 ASN ASN D . n 
D 1 481 CYS 481 460 460 CYS CYS D . n 
D 1 482 TYR 482 461 461 TYR TYR D . n 
D 1 483 HIS 483 462 ?   ?   ?   D . n 
D 1 484 ALA 484 463 ?   ?   ?   D . n 
D 1 485 TYR 485 464 ?   ?   ?   D . n 
D 1 486 PRO 486 465 ?   ?   ?   D . n 
D 1 487 ALA 487 466 ?   ?   ?   D . n 
D 1 488 HIS 488 467 ?   ?   ?   D . n 
D 1 489 ALA 489 468 ?   ?   ?   D . n 
D 1 490 ALA 490 469 ?   ?   ?   D . n 
D 1 491 PHE 491 470 ?   ?   ?   D . n 
D 1 492 GLY 492 471 ?   ?   ?   D . n 
D 1 493 GLY 493 472 ?   ?   ?   D . n 
D 1 494 TYR 494 473 ?   ?   ?   D . n 
D 1 495 LYS 495 474 ?   ?   ?   D . n 
D 1 496 GLN 496 475 ?   ?   ?   D . n 
D 1 497 SER 497 476 ?   ?   ?   D . n 
D 1 498 GLY 498 477 ?   ?   ?   D . n 
D 1 499 ILE 499 478 ?   ?   ?   D . n 
D 1 500 GLY 500 479 ?   ?   ?   D . n 
D 1 501 ARG 501 480 ?   ?   ?   D . n 
D 1 502 GLU 502 481 ?   ?   ?   D . n 
D 1 503 THR 503 482 482 THR THR D . n 
D 1 504 HIS 504 483 483 HIS HIS D . n 
D 1 505 LYS 505 484 484 LYS LYS D . n 
D 1 506 MET 506 485 485 MET MET D . n 
D 1 507 MET 507 486 486 MET MET D . n 
D 1 508 LEU 508 487 487 LEU LEU D . n 
D 1 509 ASP 509 488 488 ASP ASP D . n 
D 1 510 HIS 510 489 489 HIS HIS D . n 
D 1 511 TYR 511 490 490 TYR TYR D . n 
D 1 512 GLN 512 491 491 GLN GLN D . n 
D 1 513 GLN 513 492 492 GLN GLN D . n 
D 1 514 THR 514 493 493 THR THR D . n 
D 1 515 LYS 515 494 494 LYS LYS D . n 
D 1 516 ASN 516 495 495 ASN ASN D . n 
D 1 517 MET 517 496 496 MET MET D . n 
D 1 518 LEU 518 497 497 LEU LEU D . n 
D 1 519 VAL 519 498 498 VAL VAL D . n 
D 1 520 SER 520 499 499 SER SER D . n 
D 1 521 TYR 521 500 500 TYR TYR D . n 
D 1 522 SER 522 501 501 SER SER D . n 
D 1 523 PRO 523 502 502 PRO PRO D . n 
D 1 524 LYS 524 503 503 LYS LYS D . n 
D 1 525 LYS 525 504 504 LYS LYS D . n 
D 1 526 LEU 526 505 ?   ?   ?   D . n 
D 1 527 GLY 527 506 ?   ?   ?   D . n 
D 1 528 PHE 528 507 ?   ?   ?   D . n 
D 1 529 PHE 529 508 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        K 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   K 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 K 1 1001 1001 K K A . 
F 2 K 1 1001 1001 K K B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FM9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FM9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FM9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FM9 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005 ? 13027 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.701 ? 17634 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.866 ? 1770  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.047 ? 1918  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 2306  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9FM9 
_struct.title                        'Aldehyde dehydrogenase' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FM9 
_struct_keywords.text            'Aldehyde dehydrogenase, tetramer, oxidoreductase' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ALDH_PARDP 
_struct_ref.pdbx_db_accession          A1B4L2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MPNDQTHPFRGVNALPFEERYDNFIGGEWVAPVSGRYFTNTTPITGAEIGQIARSEAGDIELALDAAHAAKEKWGATSPA
ERANIMLKIADRMERNLELLATAETWDNGKPIRETMAADLPLAIDHFRYFAGVLRAQEGSISQIDDDTVAYHFHEPLGVV
GQIIPWNFPLLMACWKLAPAIAAGNCVVLKPAEQTPAGIMVWANLIGDLLPPGVLNIVNGFGLEAGKPLASSNRIAKIAF
TGETTTGRLIMQYASENLIPVTLELGGKSPNIFFADVAREDDDFFDKALEGFTMFALNQGEVCTCPSRVLIQESIYDKFM
ERAVQRVQAIKQGDPRESDTMIGAQASSEQKEKILSYLDIGKKEGAEVLTGGKAADLGGELSGGYYIEPTIFRGNNKMRI
FQEEIFGPVVSVTTFKDQAEALEIANDTLYGLGAGVWSRDANTCYRMGRGIKAGRVWTNCYHAYPAHAAFGGYKQSGIGR
ETHKMMLDHYQQTKNMLVSYSPKKLGFF
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FM9 A 22 ? 529 ? A1B4L2 1 ? 508 ? 1 508 
2 1 9FM9 B 22 ? 529 ? A1B4L2 1 ? 508 ? 1 508 
3 1 9FM9 C 22 ? 529 ? A1B4L2 1 ? 508 ? 1 508 
4 1 9FM9 D 22 ? 529 ? A1B4L2 1 ? 508 ? 1 508 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FM9 MET A 1  ? UNP A1B4L2 ? ? 'initiating methionine' -20 1  
1 9FM9 GLY A 2  ? UNP A1B4L2 ? ? 'expression tag'        -19 2  
1 9FM9 HIS A 3  ? UNP A1B4L2 ? ? 'expression tag'        -18 3  
1 9FM9 HIS A 4  ? UNP A1B4L2 ? ? 'expression tag'        -17 4  
1 9FM9 HIS A 5  ? UNP A1B4L2 ? ? 'expression tag'        -16 5  
1 9FM9 HIS A 6  ? UNP A1B4L2 ? ? 'expression tag'        -15 6  
1 9FM9 HIS A 7  ? UNP A1B4L2 ? ? 'expression tag'        -14 7  
1 9FM9 HIS A 8  ? UNP A1B4L2 ? ? 'expression tag'        -13 8  
1 9FM9 HIS A 9  ? UNP A1B4L2 ? ? 'expression tag'        -12 9  
1 9FM9 HIS A 10 ? UNP A1B4L2 ? ? 'expression tag'        -11 10 
1 9FM9 HIS A 11 ? UNP A1B4L2 ? ? 'expression tag'        -10 11 
1 9FM9 HIS A 12 ? UNP A1B4L2 ? ? 'expression tag'        -9  12 
1 9FM9 SER A 13 ? UNP A1B4L2 ? ? 'expression tag'        -8  13 
1 9FM9 SER A 14 ? UNP A1B4L2 ? ? 'expression tag'        -7  14 
1 9FM9 GLY A 15 ? UNP A1B4L2 ? ? 'expression tag'        -6  15 
1 9FM9 HIS A 16 ? UNP A1B4L2 ? ? 'expression tag'        -5  16 
1 9FM9 ILE A 17 ? UNP A1B4L2 ? ? 'expression tag'        -4  17 
1 9FM9 GLU A 18 ? UNP A1B4L2 ? ? 'expression tag'        -3  18 
1 9FM9 GLY A 19 ? UNP A1B4L2 ? ? 'expression tag'        -2  19 
1 9FM9 ARG A 20 ? UNP A1B4L2 ? ? 'expression tag'        -1  20 
1 9FM9 HIS A 21 ? UNP A1B4L2 ? ? 'expression tag'        0   21 
2 9FM9 MET B 1  ? UNP A1B4L2 ? ? 'initiating methionine' -20 22 
2 9FM9 GLY B 2  ? UNP A1B4L2 ? ? 'expression tag'        -19 23 
2 9FM9 HIS B 3  ? UNP A1B4L2 ? ? 'expression tag'        -18 24 
2 9FM9 HIS B 4  ? UNP A1B4L2 ? ? 'expression tag'        -17 25 
2 9FM9 HIS B 5  ? UNP A1B4L2 ? ? 'expression tag'        -16 26 
2 9FM9 HIS B 6  ? UNP A1B4L2 ? ? 'expression tag'        -15 27 
2 9FM9 HIS B 7  ? UNP A1B4L2 ? ? 'expression tag'        -14 28 
2 9FM9 HIS B 8  ? UNP A1B4L2 ? ? 'expression tag'        -13 29 
2 9FM9 HIS B 9  ? UNP A1B4L2 ? ? 'expression tag'        -12 30 
2 9FM9 HIS B 10 ? UNP A1B4L2 ? ? 'expression tag'        -11 31 
2 9FM9 HIS B 11 ? UNP A1B4L2 ? ? 'expression tag'        -10 32 
2 9FM9 HIS B 12 ? UNP A1B4L2 ? ? 'expression tag'        -9  33 
2 9FM9 SER B 13 ? UNP A1B4L2 ? ? 'expression tag'        -8  34 
2 9FM9 SER B 14 ? UNP A1B4L2 ? ? 'expression tag'        -7  35 
2 9FM9 GLY B 15 ? UNP A1B4L2 ? ? 'expression tag'        -6  36 
2 9FM9 HIS B 16 ? UNP A1B4L2 ? ? 'expression tag'        -5  37 
2 9FM9 ILE B 17 ? UNP A1B4L2 ? ? 'expression tag'        -4  38 
2 9FM9 GLU B 18 ? UNP A1B4L2 ? ? 'expression tag'        -3  39 
2 9FM9 GLY B 19 ? UNP A1B4L2 ? ? 'expression tag'        -2  40 
2 9FM9 ARG B 20 ? UNP A1B4L2 ? ? 'expression tag'        -1  41 
2 9FM9 HIS B 21 ? UNP A1B4L2 ? ? 'expression tag'        0   42 
3 9FM9 MET C 1  ? UNP A1B4L2 ? ? 'initiating methionine' -20 43 
3 9FM9 GLY C 2  ? UNP A1B4L2 ? ? 'expression tag'        -19 44 
3 9FM9 HIS C 3  ? UNP A1B4L2 ? ? 'expression tag'        -18 45 
3 9FM9 HIS C 4  ? UNP A1B4L2 ? ? 'expression tag'        -17 46 
3 9FM9 HIS C 5  ? UNP A1B4L2 ? ? 'expression tag'        -16 47 
3 9FM9 HIS C 6  ? UNP A1B4L2 ? ? 'expression tag'        -15 48 
3 9FM9 HIS C 7  ? UNP A1B4L2 ? ? 'expression tag'        -14 49 
3 9FM9 HIS C 8  ? UNP A1B4L2 ? ? 'expression tag'        -13 50 
3 9FM9 HIS C 9  ? UNP A1B4L2 ? ? 'expression tag'        -12 51 
3 9FM9 HIS C 10 ? UNP A1B4L2 ? ? 'expression tag'        -11 52 
3 9FM9 HIS C 11 ? UNP A1B4L2 ? ? 'expression tag'        -10 53 
3 9FM9 HIS C 12 ? UNP A1B4L2 ? ? 'expression tag'        -9  54 
3 9FM9 SER C 13 ? UNP A1B4L2 ? ? 'expression tag'        -8  55 
3 9FM9 SER C 14 ? UNP A1B4L2 ? ? 'expression tag'        -7  56 
3 9FM9 GLY C 15 ? UNP A1B4L2 ? ? 'expression tag'        -6  57 
3 9FM9 HIS C 16 ? UNP A1B4L2 ? ? 'expression tag'        -5  58 
3 9FM9 ILE C 17 ? UNP A1B4L2 ? ? 'expression tag'        -4  59 
3 9FM9 GLU C 18 ? UNP A1B4L2 ? ? 'expression tag'        -3  60 
3 9FM9 GLY C 19 ? UNP A1B4L2 ? ? 'expression tag'        -2  61 
3 9FM9 ARG C 20 ? UNP A1B4L2 ? ? 'expression tag'        -1  62 
3 9FM9 HIS C 21 ? UNP A1B4L2 ? ? 'expression tag'        0   63 
4 9FM9 MET D 1  ? UNP A1B4L2 ? ? 'initiating methionine' -20 64 
4 9FM9 GLY D 2  ? UNP A1B4L2 ? ? 'expression tag'        -19 65 
4 9FM9 HIS D 3  ? UNP A1B4L2 ? ? 'expression tag'        -18 66 
4 9FM9 HIS D 4  ? UNP A1B4L2 ? ? 'expression tag'        -17 67 
4 9FM9 HIS D 5  ? UNP A1B4L2 ? ? 'expression tag'        -16 68 
4 9FM9 HIS D 6  ? UNP A1B4L2 ? ? 'expression tag'        -15 69 
4 9FM9 HIS D 7  ? UNP A1B4L2 ? ? 'expression tag'        -14 70 
4 9FM9 HIS D 8  ? UNP A1B4L2 ? ? 'expression tag'        -13 71 
4 9FM9 HIS D 9  ? UNP A1B4L2 ? ? 'expression tag'        -12 72 
4 9FM9 HIS D 10 ? UNP A1B4L2 ? ? 'expression tag'        -11 73 
4 9FM9 HIS D 11 ? UNP A1B4L2 ? ? 'expression tag'        -10 74 
4 9FM9 HIS D 12 ? UNP A1B4L2 ? ? 'expression tag'        -9  75 
4 9FM9 SER D 13 ? UNP A1B4L2 ? ? 'expression tag'        -8  76 
4 9FM9 SER D 14 ? UNP A1B4L2 ? ? 'expression tag'        -7  77 
4 9FM9 GLY D 15 ? UNP A1B4L2 ? ? 'expression tag'        -6  78 
4 9FM9 HIS D 16 ? UNP A1B4L2 ? ? 'expression tag'        -5  79 
4 9FM9 ILE D 17 ? UNP A1B4L2 ? ? 'expression tag'        -4  80 
4 9FM9 GLU D 18 ? UNP A1B4L2 ? ? 'expression tag'        -3  81 
4 9FM9 GLY D 19 ? UNP A1B4L2 ? ? 'expression tag'        -2  82 
4 9FM9 ARG D 20 ? UNP A1B4L2 ? ? 'expression tag'        -1  83 
4 9FM9 HIS D 21 ? UNP A1B4L2 ? ? 'expression tag'        0   84 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 17880 ? 
1 MORE         -47   ? 
1 'SSA (A^2)'  53920 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 77  ? GLY A 96  ? GLU A 56  GLY A 75  1 ? 20 
HELX_P HELX_P2  AA2 SER A 99  ? ARG A 116 ? SER A 78  ARG A 95  1 ? 18 
HELX_P HELX_P3  AA3 ASN A 117 ? GLY A 130 ? ASN A 96  GLY A 109 1 ? 14 
HELX_P HELX_P4  AA4 PRO A 132 ? ALA A 157 ? PRO A 111 ALA A 136 1 ? 26 
HELX_P HELX_P5  AA5 PHE A 189 ? ALA A 204 ? PHE A 168 ALA A 183 1 ? 16 
HELX_P HELX_P6  AA6 PRO A 217 ? GLY A 228 ? PRO A 196 GLY A 207 1 ? 12 
HELX_P HELX_P7  AA7 ALA A 246 ? SER A 252 ? ALA A 225 SER A 231 1 ? 7  
HELX_P HELX_P8  AA8 GLU A 264 ? GLU A 277 ? GLU A 243 GLU A 256 1 ? 14 
HELX_P HELX_P9  AA9 ASP A 303 ? MET A 315 ? ASP A 282 MET A 294 1 ? 13 
HELX_P HELX_P10 AB1 PHE A 316 ? GLU A 322 ? PHE A 295 GLU A 301 5 ? 7  
HELX_P HELX_P11 AB2 ILE A 336 ? ALA A 350 ? ILE A 315 ALA A 329 1 ? 15 
HELX_P HELX_P12 AB3 SER A 368 ? GLU A 385 ? SER A 347 GLU A 364 1 ? 18 
HELX_P HELX_P13 AB4 GLY A 399 ? GLY A 405 ? GLY A 378 GLY A 384 5 ? 7  
HELX_P HELX_P14 AB5 MET A 419 ? GLU A 424 ? MET A 398 GLU A 403 1 ? 6  
HELX_P HELX_P15 AB6 ASP A 438 ? ASP A 448 ? ASP A 417 ASP A 427 1 ? 11 
HELX_P HELX_P16 AB7 ASP A 461 ? ILE A 472 ? ASP A 440 ILE A 451 1 ? 12 
HELX_P HELX_P17 AB8 HIS A 504 ? HIS A 510 ? HIS A 483 HIS A 489 5 ? 7  
HELX_P HELX_P18 AB9 GLY B 79  ? ALA B 97  ? GLY B 58  ALA B 76  1 ? 19 
HELX_P HELX_P19 AC1 ALA B 101 ? ASN B 117 ? ALA B 80  ASN B 96  1 ? 17 
HELX_P HELX_P20 AC2 ASN B 117 ? GLY B 130 ? ASN B 96  GLY B 109 1 ? 14 
HELX_P HELX_P21 AC3 PRO B 132 ? ALA B 139 ? PRO B 111 ALA B 118 1 ? 8  
HELX_P HELX_P22 AC4 ALA B 139 ? GLN B 158 ? ALA B 118 GLN B 137 1 ? 20 
HELX_P HELX_P23 AC5 LEU B 191 ? ALA B 204 ? LEU B 170 ALA B 183 1 ? 14 
HELX_P HELX_P24 AC6 ALA B 218 ? ILE B 227 ? ALA B 197 ILE B 206 1 ? 10 
HELX_P HELX_P25 AC7 GLY B 247 ? SER B 252 ? GLY B 226 SER B 231 1 ? 6  
HELX_P HELX_P26 AC8 GLU B 264 ? SER B 276 ? GLU B 243 SER B 255 1 ? 13 
HELX_P HELX_P27 AC9 ASP B 303 ? THR B 314 ? ASP B 282 THR B 293 1 ? 12 
HELX_P HELX_P28 AD1 MET B 315 ? GLU B 322 ? MET B 294 GLU B 301 5 ? 8  
HELX_P HELX_P29 AD2 ILE B 336 ? ALA B 350 ? ILE B 315 ALA B 329 1 ? 15 
HELX_P HELX_P30 AD3 SER B 368 ? GLY B 386 ? SER B 347 GLY B 365 1 ? 19 
HELX_P HELX_P31 AD4 MET B 419 ? GLU B 424 ? MET B 398 GLU B 403 1 ? 6  
HELX_P HELX_P32 AD5 ASP B 438 ? ASP B 448 ? ASP B 417 ASP B 427 1 ? 11 
HELX_P HELX_P33 AD6 ASP B 461 ? ILE B 472 ? ASP B 440 ILE B 451 1 ? 12 
HELX_P HELX_P34 AD7 HIS B 504 ? ASP B 509 ? HIS B 483 ASP B 488 5 ? 6  
HELX_P HELX_P35 AD8 GLY C 79  ? GLY C 96  ? GLY C 58  GLY C 75  1 ? 18 
HELX_P HELX_P36 AD9 SER C 99  ? ASN C 117 ? SER C 78  ASN C 96  1 ? 19 
HELX_P HELX_P37 AE1 ASN C 117 ? GLY C 130 ? ASN C 96  GLY C 109 1 ? 14 
HELX_P HELX_P38 AE2 GLU C 135 ? ASP C 140 ? GLU C 114 ASP C 119 1 ? 6  
HELX_P HELX_P39 AE3 ASP C 140 ? GLN C 158 ? ASP C 119 GLN C 137 1 ? 19 
HELX_P HELX_P40 AE4 LEU C 191 ? ALA C 204 ? LEU C 170 ALA C 183 1 ? 14 
HELX_P HELX_P41 AE5 ALA C 218 ? GLY C 228 ? ALA C 197 GLY C 207 1 ? 11 
HELX_P HELX_P42 AE6 ASP C 229 ? LEU C 231 ? ASP C 208 LEU C 210 5 ? 3  
HELX_P HELX_P43 AE7 ALA C 246 ? SER C 252 ? ALA C 225 SER C 231 1 ? 7  
HELX_P HELX_P44 AE8 ALA C 296 ? ARG C 300 ? ALA C 275 ARG C 279 5 ? 5  
HELX_P HELX_P45 AE9 ASP C 304 ? THR C 314 ? ASP C 283 THR C 293 1 ? 11 
HELX_P HELX_P46 AF1 LEU C 318 ? GLU C 322 ? LEU C 297 GLU C 301 5 ? 5  
HELX_P HELX_P47 AF2 ILE C 336 ? GLN C 349 ? ILE C 315 GLN C 328 1 ? 14 
HELX_P HELX_P48 AF3 SER C 368 ? GLY C 386 ? SER C 347 GLY C 365 1 ? 19 
HELX_P HELX_P49 AF4 ASP C 438 ? ASN C 447 ? ASP C 417 ASN C 426 1 ? 10 
HELX_P HELX_P50 AF5 ASP C 461 ? ILE C 472 ? ASP C 440 ILE C 451 1 ? 12 
HELX_P HELX_P51 AF6 ASP D 80  ? GLY D 96  ? ASP D 59  GLY D 75  1 ? 17 
HELX_P HELX_P52 AF7 SER D 99  ? ASN D 117 ? SER D 78  ASN D 96  1 ? 19 
HELX_P HELX_P53 AF8 ASP D 140 ? GLN D 158 ? ASP D 119 GLN D 137 1 ? 19 
HELX_P HELX_P54 AF9 LEU D 191 ? GLY D 205 ? LEU D 170 GLY D 184 1 ? 15 
HELX_P HELX_P55 AG1 MET D 221 ? LEU D 231 ? MET D 200 LEU D 210 1 ? 11 
HELX_P HELX_P56 AG2 ASP D 438 ? ALA D 446 ? ASP D 417 ALA D 425 1 ? 9  
HELX_P HELX_P57 AG3 THR D 464 ? GLY D 471 ? THR D 443 GLY D 450 1 ? 8  
HELX_P HELX_P58 AG4 HIS D 504 ? LEU D 508 ? HIS D 483 LEU D 487 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A ASN 61  OD1 ? ? ? 1_555 E K . K ? ? A ASN 40  A K 1001 1_555 ? ? ? ? ? ? ? 2.690 ? ? 
metalc2 metalc ? ? A THR 62  O   ? ? ? 1_555 E K . K ? ? A THR 41  A K 1001 1_555 ? ? ? ? ? ? ? 3.074 ? ? 
metalc3 metalc ? ? A ASP 128 O   ? ? ? 1_555 E K . K ? ? A ASP 107 A K 1001 1_555 ? ? ? ? ? ? ? 2.676 ? ? 
metalc4 metalc ? ? A ASP 128 OD1 ? ? ? 1_555 E K . K ? ? A ASP 107 A K 1001 1_555 ? ? ? ? ? ? ? 2.701 ? ? 
metalc5 metalc ? ? A GLN 215 O   ? ? ? 1_555 E K . K ? ? A GLN 194 A K 1001 1_555 ? ? ? ? ? ? ? 2.263 ? ? 
metalc6 metalc ? ? B THR 62  O   ? ? ? 1_555 F K . K ? ? B THR 41  B K 1001 1_555 ? ? ? ? ? ? ? 2.946 ? ? 
metalc7 metalc ? ? B ASP 128 O   ? ? ? 1_555 F K . K ? ? B ASP 107 B K 1001 1_555 ? ? ? ? ? ? ? 2.792 ? ? 
metalc8 metalc ? ? B ASP 128 OD1 ? ? ? 1_555 F K . K ? ? B ASP 107 B K 1001 1_555 ? ? ? ? ? ? ? 2.826 ? ? 
metalc9 metalc ? ? B GLN 215 O   ? ? ? 1_555 F K . K ? ? B GLN 194 B K 1001 1_555 ? ? ? ? ? ? ? 2.270 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASN 61  ? A ASN 40  ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A THR 62  ? A THR 41  ? 1_555 85.6  ? 
2  OD1 ? A ASN 61  ? A ASN 40  ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A ASP 128 ? A ASP 107 ? 1_555 128.6 ? 
3  O   ? A THR 62  ? A THR 41  ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A ASP 128 ? A ASP 107 ? 1_555 104.2 ? 
4  OD1 ? A ASN 61  ? A ASN 40  ? 1_555 K ? E K . ? A K 1001 ? 1_555 OD1 ? A ASP 128 ? A ASP 107 ? 1_555 68.2  ? 
5  O   ? A THR 62  ? A THR 41  ? 1_555 K ? E K . ? A K 1001 ? 1_555 OD1 ? A ASP 128 ? A ASP 107 ? 1_555 114.3 ? 
6  O   ? A ASP 128 ? A ASP 107 ? 1_555 K ? E K . ? A K 1001 ? 1_555 OD1 ? A ASP 128 ? A ASP 107 ? 1_555 61.7  ? 
7  OD1 ? A ASN 61  ? A ASN 40  ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A GLN 215 ? A GLN 194 ? 1_555 82.6  ? 
8  O   ? A THR 62  ? A THR 41  ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A GLN 215 ? A GLN 194 ? 1_555 130.9 ? 
9  O   ? A ASP 128 ? A ASP 107 ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A GLN 215 ? A GLN 194 ? 1_555 120.2 ? 
10 OD1 ? A ASP 128 ? A ASP 107 ? 1_555 K ? E K . ? A K 1001 ? 1_555 O   ? A GLN 215 ? A GLN 194 ? 1_555 104.9 ? 
11 O   ? B THR 62  ? B THR 41  ? 1_555 K ? F K . ? B K 1001 ? 1_555 O   ? B ASP 128 ? B ASP 107 ? 1_555 96.8  ? 
12 O   ? B THR 62  ? B THR 41  ? 1_555 K ? F K . ? B K 1001 ? 1_555 OD1 ? B ASP 128 ? B ASP 107 ? 1_555 91.5  ? 
13 O   ? B ASP 128 ? B ASP 107 ? 1_555 K ? F K . ? B K 1001 ? 1_555 OD1 ? B ASP 128 ? B ASP 107 ? 1_555 66.6  ? 
14 O   ? B THR 62  ? B THR 41  ? 1_555 K ? F K . ? B K 1001 ? 1_555 O   ? B GLN 215 ? B GLN 194 ? 1_555 150.0 ? 
15 O   ? B ASP 128 ? B ASP 107 ? 1_555 K ? F K . ? B K 1001 ? 1_555 O   ? B GLN 215 ? B GLN 194 ? 1_555 111.7 ? 
16 OD1 ? B ASP 128 ? B ASP 107 ? 1_555 K ? F K . ? B K 1001 ? 1_555 O   ? B GLN 215 ? B GLN 194 ? 1_555 107.8 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2  ? 
AA2 ? 9  ? 
AA3 ? 5  ? 
AA4 ? 14 ? 
AA5 ? 3  ? 
AA6 ? 2  ? 
AA7 ? 4  ? 
AA8 ? 2  ? 
AA9 ? 3  ? 
AB1 ? 6  ? 
AB2 ? 3  ? 
AB3 ? 2  ? 
AB4 ? 2  ? 
AB5 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? parallel      
AA2 4  5  ? parallel      
AA2 5  6  ? parallel      
AA2 6  7  ? parallel      
AA2 7  8  ? parallel      
AA2 8  9  ? parallel      
AA3 1  2  ? parallel      
AA3 2  3  ? parallel      
AA3 3  4  ? parallel      
AA3 4  5  ? parallel      
AA4 1  2  ? anti-parallel 
AA4 2  3  ? parallel      
AA4 3  4  ? parallel      
AA4 4  5  ? parallel      
AA4 5  6  ? parallel      
AA4 6  7  ? parallel      
AA4 7  8  ? parallel      
AA4 8  9  ? anti-parallel 
AA4 9  10 ? anti-parallel 
AA4 10 11 ? anti-parallel 
AA4 11 12 ? anti-parallel 
AA4 12 13 ? anti-parallel 
AA4 13 14 ? parallel      
AA5 1  2  ? parallel      
AA5 2  3  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA7 1  2  ? parallel      
AA7 2  3  ? parallel      
AA7 3  4  ? parallel      
AA8 1  2  ? anti-parallel 
AA9 1  2  ? parallel      
AA9 2  3  ? parallel      
AB1 1  2  ? parallel      
AB1 2  3  ? parallel      
AB1 3  4  ? parallel      
AB1 4  5  ? anti-parallel 
AB1 5  6  ? anti-parallel 
AB2 1  2  ? parallel      
AB2 2  3  ? parallel      
AB3 1  2  ? parallel      
AB4 1  2  ? parallel      
AB5 1  2  ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  TYR A 58  ? THR A 63  ? TYR A 37  THR A 42  
AA1 2  ALA A 68  ? ALA A 74  ? ALA A 47  ALA A 53  
AA2 1  SER A 161 ? GLN A 164 ? SER A 140 GLN A 143 
AA2 2  THR A 169 ? PRO A 177 ? THR A 148 PRO A 156 
AA2 3  GLN A 512 ? SER A 520 ? GLN A 491 SER A 499 
AA2 4  ARG B 476 ? THR B 479 ? ARG B 455 THR B 458 
AA2 5  GLY B 454 ? TRP B 458 ? GLY B 433 TRP B 437 
AA2 6  LYS B 289 ? PHE B 294 ? LYS B 268 PHE B 273 
AA2 7  CYS B 326 ? GLN B 333 ? CYS B 305 GLN B 312 
AA2 8  VAL B 430 ? PHE B 436 ? VAL B 409 PHE B 415 
AA2 9  THR B 411 ? ILE B 412 ? THR B 390 ILE B 391 
AA3 1  LEU A 236 ? ILE A 238 ? LEU A 215 ILE A 217 
AA3 2  CYS A 207 ? LYS A 211 ? CYS A 186 LYS A 190 
AA3 3  VAL A 180 ? ILE A 184 ? VAL A 159 ILE A 163 
AA3 4  ILE A 259 ? GLY A 263 ? ILE A 238 GLY A 242 
AA3 5  VAL A 282 ? LEU A 286 ? VAL A 261 LEU A 265 
AA4 1  GLU A 388 ? THR A 391 ? GLU A 367 THR A 370 
AA4 2  THR A 411 ? ARG A 414 ? THR A 390 ARG A 393 
AA4 3  VAL A 430 ? PHE A 436 ? VAL A 409 PHE A 415 
AA4 4  ARG A 329 ? GLN A 333 ? ARG A 308 GLN A 312 
AA4 5  PRO A 291 ? PHE A 294 ? PRO A 270 PHE A 273 
AA4 6  GLY A 454 ? TRP A 458 ? GLY A 433 TRP A 437 
AA4 7  ARG A 476 ? THR A 479 ? ARG A 455 THR A 458 
AA4 8  GLN B 512 ? SER B 520 ? GLN B 491 SER B 499 
AA4 9  THR B 169 ? PRO B 177 ? THR B 148 PRO B 156 
AA4 10 GLY B 160 ? GLN B 164 ? GLY B 139 GLN B 143 
AA4 11 GLY C 160 ? GLN C 164 ? GLY C 139 GLN C 143 
AA4 12 THR C 169 ? PRO C 177 ? THR C 148 PRO C 156 
AA4 13 GLN C 512 ? SER C 520 ? GLN C 491 SER C 499 
AA4 14 VAL D 477 ? THR D 479 ? VAL D 456 THR D 458 
AA5 1  ARG B 41  ? TYR B 42  ? ARG B 20  TYR B 21  
AA5 2  GLU B 69  ? ALA B 74  ? GLU B 48  ALA B 53  
AA5 3  TYR B 58  ? THR B 62  ? TYR B 37  THR B 41  
AA6 1  ASN B 44  ? ILE B 46  ? ASN B 23  ILE B 25  
AA6 2  GLU B 49  ? VAL B 51  ? GLU B 28  VAL B 30  
AA7 1  LEU B 236 ? ILE B 238 ? LEU B 215 ILE B 217 
AA7 2  CYS B 207 ? LYS B 211 ? CYS B 186 LYS B 190 
AA7 3  VAL B 180 ? ILE B 184 ? VAL B 159 ILE B 163 
AA7 4  LYS B 258 ? PHE B 261 ? LYS B 237 PHE B 240 
AA8 1  TYR C 58  ? THR C 62  ? TYR C 37  THR C 41  
AA8 2  GLU C 69  ? ALA C 74  ? GLU C 48  ALA C 53  
AA9 1  VAL C 180 ? ILE C 185 ? VAL C 159 ILE C 164 
AA9 2  CYS C 207 ? PRO C 212 ? CYS C 186 PRO C 191 
AA9 3  LEU C 236 ? ILE C 238 ? LEU C 215 ILE C 217 
AB1 1  ASN C 292 ? PHE C 294 ? ASN C 271 PHE C 273 
AB1 2  ALA C 455 ? TRP C 458 ? ALA C 434 TRP C 437 
AB1 3  ARG C 476 ? THR C 479 ? ARG C 455 THR C 458 
AB1 4  LYS D 515 ? SER D 520 ? LYS D 494 SER D 499 
AB1 5  THR D 169 ? PHE D 174 ? THR D 148 PHE D 153 
AB1 6  GLN D 164 ? ASP D 166 ? GLN D 143 ASP D 145 
AB2 1  ARG C 329 ? GLN C 333 ? ARG C 308 GLN C 312 
AB2 2  VAL C 430 ? PHE C 436 ? VAL C 409 PHE C 415 
AB2 3  THR C 411 ? ARG C 414 ? THR C 390 ARG C 393 
AB3 1  VAL D 180 ? GLY D 182 ? VAL D 159 GLY D 161 
AB3 2  CYS D 207 ? VAL D 209 ? CYS D 186 VAL D 188 
AB4 1  ILE D 293 ? PHE D 294 ? ILE D 272 PHE D 273 
AB4 2  VAL D 457 ? TRP D 458 ? VAL D 436 TRP D 437 
AB5 1  LEU D 331 ? ILE D 332 ? LEU D 310 ILE D 311 
AB5 2  THR D 434 ? THR D 435 ? THR D 413 THR D 414 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N THR A 63  ? N THR A 42  O ALA A 68  ? O ALA A 47  
AA2 1  2  N SER A 161 ? N SER A 140 O HIS A 173 ? O HIS A 152 
AA2 2  3  N VAL A 170 ? N VAL A 149 O VAL A 519 ? O VAL A 498 
AA2 3  4  N LEU A 518 ? N LEU A 497 O THR B 479 ? O THR B 458 
AA2 4  5  O TRP B 478 ? O TRP B 457 N VAL B 457 ? N VAL B 436 
AA2 5  6  O GLY B 456 ? O GLY B 435 N ILE B 293 ? N ILE B 272 
AA2 6  7  N ASN B 292 ? N ASN B 271 O LEU B 331 ? O LEU B 310 
AA2 7  8  N SER B 328 ? N SER B 307 O SER B 432 ? O SER B 411 
AA2 8  9  O VAL B 431 ? O VAL B 410 N THR B 411 ? N THR B 390 
AA3 1  2  O ASN A 237 ? O ASN A 216 N LEU A 210 ? N LEU A 189 
AA3 2  3  O LYS A 211 ? O LYS A 190 N GLN A 183 ? N GLN A 162 
AA3 3  4  N ILE A 184 ? N ILE A 163 O ALA A 260 ? O ALA A 239 
AA3 4  5  N PHE A 261 ? N PHE A 240 O THR A 283 ? O THR A 262 
AA4 1  2  N LEU A 390 ? N LEU A 369 O ILE A 412 ? O ILE A 391 
AA4 2  3  N PHE A 413 ? N PHE A 392 O VAL A 431 ? O VAL A 410 
AA4 3  4  O THR A 434 ? O THR A 413 N VAL A 330 ? N VAL A 309 
AA4 4  5  O LEU A 331 ? O LEU A 310 N PHE A 294 ? N PHE A 273 
AA4 5  6  N ILE A 293 ? N ILE A 272 O GLY A 456 ? O GLY A 435 
AA4 6  7  N VAL A 457 ? N VAL A 436 O TRP A 478 ? O TRP A 457 
AA4 7  8  N VAL A 477 ? N VAL A 456 O ASN B 516 ? O ASN B 495 
AA4 8  9  O MET B 517 ? O MET B 496 N TYR B 172 ? N TYR B 151 
AA4 9  10 O HIS B 173 ? O HIS B 152 N SER B 161 ? N SER B 140 
AA4 10 11 N GLY B 160 ? N GLY B 139 O ILE C 162 ? O ILE C 141 
AA4 11 12 N SER C 163 ? N SER C 142 O ALA C 171 ? O ALA C 150 
AA4 12 13 N VAL C 170 ? N VAL C 149 O VAL C 519 ? O VAL C 498 
AA4 13 14 N ASN C 516 ? N ASN C 495 O VAL D 477 ? O VAL D 456 
AA5 1  2  N TYR B 42  ? N TYR B 21  O ALA B 74  ? O ALA B 53  
AA5 2  3  O ILE B 70  ? O ILE B 49  N ASN B 61  ? N ASN B 40  
AA6 1  2  N ASN B 44  ? N ASN B 23  O VAL B 51  ? O VAL B 30  
AA7 1  2  O ASN B 237 ? O ASN B 216 N LEU B 210 ? N LEU B 189 
AA7 2  3  O LYS B 211 ? O LYS B 190 N GLN B 183 ? N GLN B 162 
AA7 3  4  N GLY B 182 ? N GLY B 161 O LYS B 258 ? O LYS B 237 
AA8 1  2  N ASN C 61  ? N ASN C 40  O ILE C 70  ? O ILE C 49  
AA9 1  2  N GLN C 183 ? N GLN C 162 O VAL C 209 ? O VAL C 188 
AA9 2  3  N LEU C 210 ? N LEU C 189 O ASN C 237 ? O ASN C 216 
AB1 1  2  N ILE C 293 ? N ILE C 272 O TRP C 458 ? O TRP C 437 
AB1 2  3  N ALA C 455 ? N ALA C 434 O TRP C 478 ? O TRP C 457 
AB1 3  4  N VAL C 477 ? N VAL C 456 O ASN D 516 ? O ASN D 495 
AB1 4  5  O VAL D 519 ? O VAL D 498 N VAL D 170 ? N VAL D 149 
AB1 5  6  O THR D 169 ? O THR D 148 N ASP D 166 ? N ASP D 145 
AB2 1  2  N VAL C 330 ? N VAL C 309 O THR C 434 ? O THR C 413 
AB2 2  3  O VAL C 431 ? O VAL C 410 N PHE C 413 ? N PHE C 392 
AB3 1  2  N VAL D 181 ? N VAL D 160 O CYS D 207 ? O CYS D 186 
AB4 1  2  N ILE D 293 ? N ILE D 272 O TRP D 458 ? O TRP D 437 
AB5 1  2  N ILE D 332 ? N ILE D 311 O THR D 434 ? O THR D 413 
# 
_pdbx_entry_details.entry_id                   9FM9 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 20  ? ? 61.56   62.28   
2  1 SER A 231 ? ? -93.14  54.13   
3  1 LEU A 258 ? ? 74.80   -0.16   
4  1 ALA A 275 ? ? -69.05  1.14    
5  1 ASP A 281 ? ? 39.13   32.91   
6  1 MET A 294 ? ? -65.37  2.65    
7  1 SER A 314 ? ? -92.37  44.79   
8  1 TYR A 464 ? ? -117.09 55.77   
9  1 HIS A 467 ? ? 80.74   20.11   
10 1 ASP B 22  ? ? -79.99  -168.16 
11 1 ALA B 57  ? ? -66.48  3.45    
12 1 ALA B 118 ? ? -95.35  -60.10  
13 1 ALA B 275 ? ? 75.60   -4.38   
14 1 GLU B 301 ? ? -90.08  50.47   
15 1 GLU B 337 ? ? -115.37 -75.98  
16 1 SER B 338 ? ? -157.60 -2.89   
17 1 GLU B 380 ? ? -83.46  48.50   
18 1 LYS B 474 ? ? -160.21 -157.58 
19 1 SER B 476 ? ? -143.98 16.44   
20 1 PRO B 502 ? ? -87.02  49.60   
21 1 LEU C 15  ? ? -50.01  109.74  
22 1 GLU C 18  ? ? -93.78  -72.34  
23 1 GLU C 19  ? ? 172.89  163.09  
24 1 ALA C 57  ? ? -144.01 -15.96  
25 1 ALA C 117 ? ? -130.45 -30.38  
26 1 ALA C 197 ? ? 68.28   -3.92   
27 1 ASP C 281 ? ? -100.16 65.62   
28 1 ASP C 283 ? ? -144.48 -26.65  
29 1 THR C 304 ? ? -99.95  36.52   
30 1 ARG C 336 ? ? -98.63  56.06   
31 1 GLU C 337 ? ? -114.74 -75.42  
32 1 SER C 338 ? ? -150.94 -27.43  
33 1 GLN C 345 ? ? -81.78  -80.39  
34 1 ALA C 346 ? ? -149.50 -29.03  
35 1 SER C 347 ? ? -177.00 -172.26 
36 1 ALA C 366 ? ? -141.73 50.95   
37 1 GLU C 367 ? ? -36.13  119.65  
38 1 LEU C 429 ? ? -95.39  33.88   
39 1 TYR C 430 ? ? -148.37 -157.47 
40 1 ALA C 453 ? ? -78.07  -169.46 
41 1 TYR C 464 ? ? -117.13 75.38   
42 1 HIS C 467 ? ? 79.25   -2.09   
43 1 TYR C 490 ? ? -99.70  30.46   
44 1 SER D 142 ? ? -35.39  120.62  
45 1 HIS D 154 ? ? -118.92 50.81   
46 1 GLU D 155 ? ? -47.01  150.40  
47 1 PHE D 274 ? ? -96.44  54.29   
48 1 ALA D 275 ? ? 66.91   -5.96   
49 1 LEU D 310 ? ? -100.02 77.89   
50 1 ALA D 441 ? ? 66.49   -4.55   
51 1 ARG D 455 ? ? -160.86 117.26  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9FM9 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9FM9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               185597 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 PDEN_2366 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9FM9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9FM9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9FM9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -20 ? A MET 1   
2   1 Y 1 A GLY -19 ? A GLY 2   
3   1 Y 1 A HIS -18 ? A HIS 3   
4   1 Y 1 A HIS -17 ? A HIS 4   
5   1 Y 1 A HIS -16 ? A HIS 5   
6   1 Y 1 A HIS -15 ? A HIS 6   
7   1 Y 1 A HIS -14 ? A HIS 7   
8   1 Y 1 A HIS -13 ? A HIS 8   
9   1 Y 1 A HIS -12 ? A HIS 9   
10  1 Y 1 A HIS -11 ? A HIS 10  
11  1 Y 1 A HIS -10 ? A HIS 11  
12  1 Y 1 A HIS -9  ? A HIS 12  
13  1 Y 1 A SER -8  ? A SER 13  
14  1 Y 1 A SER -7  ? A SER 14  
15  1 Y 1 A GLY -6  ? A GLY 15  
16  1 Y 1 A HIS -5  ? A HIS 16  
17  1 Y 1 A ILE -4  ? A ILE 17  
18  1 Y 1 A GLU -3  ? A GLU 18  
19  1 Y 1 A GLY -2  ? A GLY 19  
20  1 Y 1 A ARG -1  ? A ARG 20  
21  1 Y 1 A HIS 0   ? A HIS 21  
22  1 Y 1 A MET 1   ? A MET 22  
23  1 Y 1 A PRO 2   ? A PRO 23  
24  1 Y 1 A ASN 3   ? A ASN 24  
25  1 Y 1 A ASP 4   ? A ASP 25  
26  1 Y 1 A GLN 5   ? A GLN 26  
27  1 Y 1 A THR 6   ? A THR 27  
28  1 Y 1 A HIS 7   ? A HIS 28  
29  1 Y 1 A PRO 8   ? A PRO 29  
30  1 Y 1 A PHE 9   ? A PHE 30  
31  1 Y 1 B MET -20 ? B MET 1   
32  1 Y 1 B GLY -19 ? B GLY 2   
33  1 Y 1 B HIS -18 ? B HIS 3   
34  1 Y 1 B HIS -17 ? B HIS 4   
35  1 Y 1 B HIS -16 ? B HIS 5   
36  1 Y 1 B HIS -15 ? B HIS 6   
37  1 Y 1 B HIS -14 ? B HIS 7   
38  1 Y 1 B HIS -13 ? B HIS 8   
39  1 Y 1 B HIS -12 ? B HIS 9   
40  1 Y 1 B HIS -11 ? B HIS 10  
41  1 Y 1 B HIS -10 ? B HIS 11  
42  1 Y 1 B HIS -9  ? B HIS 12  
43  1 Y 1 B SER -8  ? B SER 13  
44  1 Y 1 B SER -7  ? B SER 14  
45  1 Y 1 B GLY -6  ? B GLY 15  
46  1 Y 1 B HIS -5  ? B HIS 16  
47  1 Y 1 B ILE -4  ? B ILE 17  
48  1 Y 1 B GLU -3  ? B GLU 18  
49  1 Y 1 B GLY -2  ? B GLY 19  
50  1 Y 1 B ARG -1  ? B ARG 20  
51  1 Y 1 B HIS 0   ? B HIS 21  
52  1 Y 1 B MET 1   ? B MET 22  
53  1 Y 1 B PRO 2   ? B PRO 23  
54  1 Y 1 B ASN 3   ? B ASN 24  
55  1 Y 1 B ASP 4   ? B ASP 25  
56  1 Y 1 B GLN 5   ? B GLN 26  
57  1 Y 1 B THR 6   ? B THR 27  
58  1 Y 1 B HIS 7   ? B HIS 28  
59  1 Y 1 B PRO 8   ? B PRO 29  
60  1 Y 1 B PHE 9   ? B PHE 30  
61  1 Y 1 B ARG 10  ? B ARG 31  
62  1 Y 1 C MET -20 ? C MET 1   
63  1 Y 1 C GLY -19 ? C GLY 2   
64  1 Y 1 C HIS -18 ? C HIS 3   
65  1 Y 1 C HIS -17 ? C HIS 4   
66  1 Y 1 C HIS -16 ? C HIS 5   
67  1 Y 1 C HIS -15 ? C HIS 6   
68  1 Y 1 C HIS -14 ? C HIS 7   
69  1 Y 1 C HIS -13 ? C HIS 8   
70  1 Y 1 C HIS -12 ? C HIS 9   
71  1 Y 1 C HIS -11 ? C HIS 10  
72  1 Y 1 C HIS -10 ? C HIS 11  
73  1 Y 1 C HIS -9  ? C HIS 12  
74  1 Y 1 C SER -8  ? C SER 13  
75  1 Y 1 C SER -7  ? C SER 14  
76  1 Y 1 C GLY -6  ? C GLY 15  
77  1 Y 1 C HIS -5  ? C HIS 16  
78  1 Y 1 C ILE -4  ? C ILE 17  
79  1 Y 1 C GLU -3  ? C GLU 18  
80  1 Y 1 C GLY -2  ? C GLY 19  
81  1 Y 1 C ARG -1  ? C ARG 20  
82  1 Y 1 C HIS 0   ? C HIS 21  
83  1 Y 1 C MET 1   ? C MET 22  
84  1 Y 1 C PRO 2   ? C PRO 23  
85  1 Y 1 C ASN 3   ? C ASN 24  
86  1 Y 1 C ASP 4   ? C ASP 25  
87  1 Y 1 C GLN 5   ? C GLN 26  
88  1 Y 1 C THR 6   ? C THR 27  
89  1 Y 1 C HIS 7   ? C HIS 28  
90  1 Y 1 C PRO 8   ? C PRO 29  
91  1 Y 1 C PHE 9   ? C PHE 30  
92  1 Y 1 C ARG 10  ? C ARG 31  
93  1 Y 1 C ALA 239 ? C ALA 260 
94  1 Y 1 C PHE 240 ? C PHE 261 
95  1 Y 1 C THR 241 ? C THR 262 
96  1 Y 1 C GLY 242 ? C GLY 263 
97  1 Y 1 C GLU 243 ? C GLU 264 
98  1 Y 1 C THR 244 ? C THR 265 
99  1 Y 1 C THR 245 ? C THR 266 
100 1 Y 1 C THR 246 ? C THR 267 
101 1 Y 1 C GLY 247 ? C GLY 268 
102 1 Y 1 C ARG 248 ? C ARG 269 
103 1 Y 1 C LEU 249 ? C LEU 270 
104 1 Y 1 C ILE 250 ? C ILE 271 
105 1 Y 1 C MET 251 ? C MET 272 
106 1 Y 1 C GLN 252 ? C GLN 273 
107 1 Y 1 C TYR 253 ? C TYR 274 
108 1 Y 1 C ALA 254 ? C ALA 275 
109 1 Y 1 C SER 255 ? C SER 276 
110 1 Y 1 C GLU 256 ? C GLU 277 
111 1 Y 1 C ASN 257 ? C ASN 278 
112 1 Y 1 C LEU 258 ? C LEU 279 
113 1 Y 1 C ILE 259 ? C ILE 280 
114 1 Y 1 C PRO 260 ? C PRO 281 
115 1 Y 1 C VAL 261 ? C VAL 282 
116 1 Y 1 C THR 262 ? C THR 283 
117 1 Y 1 C LEU 263 ? C LEU 284 
118 1 Y 1 C GLU 264 ? C GLU 285 
119 1 Y 1 C LEU 265 ? C LEU 286 
120 1 Y 1 C PHE 470 ? C PHE 491 
121 1 Y 1 C GLY 471 ? C GLY 492 
122 1 Y 1 C GLY 472 ? C GLY 493 
123 1 Y 1 C TYR 473 ? C TYR 494 
124 1 Y 1 C LYS 474 ? C LYS 495 
125 1 Y 1 C GLN 475 ? C GLN 496 
126 1 Y 1 C SER 476 ? C SER 497 
127 1 Y 1 C GLY 477 ? C GLY 498 
128 1 Y 1 C ILE 478 ? C ILE 499 
129 1 Y 1 C GLY 479 ? C GLY 500 
130 1 Y 1 C ARG 480 ? C ARG 501 
131 1 Y 1 C GLU 481 ? C GLU 502 
132 1 Y 1 C LEU 505 ? C LEU 526 
133 1 Y 1 C GLY 506 ? C GLY 527 
134 1 Y 1 C PHE 507 ? C PHE 528 
135 1 Y 1 C PHE 508 ? C PHE 529 
136 1 Y 1 D MET -20 ? D MET 1   
137 1 Y 1 D GLY -19 ? D GLY 2   
138 1 Y 1 D HIS -18 ? D HIS 3   
139 1 Y 1 D HIS -17 ? D HIS 4   
140 1 Y 1 D HIS -16 ? D HIS 5   
141 1 Y 1 D HIS -15 ? D HIS 6   
142 1 Y 1 D HIS -14 ? D HIS 7   
143 1 Y 1 D HIS -13 ? D HIS 8   
144 1 Y 1 D HIS -12 ? D HIS 9   
145 1 Y 1 D HIS -11 ? D HIS 10  
146 1 Y 1 D HIS -10 ? D HIS 11  
147 1 Y 1 D HIS -9  ? D HIS 12  
148 1 Y 1 D SER -8  ? D SER 13  
149 1 Y 1 D SER -7  ? D SER 14  
150 1 Y 1 D GLY -6  ? D GLY 15  
151 1 Y 1 D HIS -5  ? D HIS 16  
152 1 Y 1 D ILE -4  ? D ILE 17  
153 1 Y 1 D GLU -3  ? D GLU 18  
154 1 Y 1 D GLY -2  ? D GLY 19  
155 1 Y 1 D ARG -1  ? D ARG 20  
156 1 Y 1 D HIS 0   ? D HIS 21  
157 1 Y 1 D MET 1   ? D MET 22  
158 1 Y 1 D PRO 2   ? D PRO 23  
159 1 Y 1 D ASN 3   ? D ASN 24  
160 1 Y 1 D ASP 4   ? D ASP 25  
161 1 Y 1 D GLN 5   ? D GLN 26  
162 1 Y 1 D THR 6   ? D THR 27  
163 1 Y 1 D HIS 7   ? D HIS 28  
164 1 Y 1 D PRO 8   ? D PRO 29  
165 1 Y 1 D PHE 9   ? D PHE 30  
166 1 Y 1 D ARG 10  ? D ARG 31  
167 1 Y 1 D GLY 11  ? D GLY 32  
168 1 Y 1 D VAL 12  ? D VAL 33  
169 1 Y 1 D ASN 13  ? D ASN 34  
170 1 Y 1 D ALA 14  ? D ALA 35  
171 1 Y 1 D LEU 15  ? D LEU 36  
172 1 Y 1 D PRO 16  ? D PRO 37  
173 1 Y 1 D PHE 17  ? D PHE 38  
174 1 Y 1 D GLU 18  ? D GLU 39  
175 1 Y 1 D GLU 19  ? D GLU 40  
176 1 Y 1 D ARG 20  ? D ARG 41  
177 1 Y 1 D TYR 21  ? D TYR 42  
178 1 Y 1 D ASP 22  ? D ASP 43  
179 1 Y 1 D ASN 23  ? D ASN 44  
180 1 Y 1 D PHE 24  ? D PHE 45  
181 1 Y 1 D ILE 25  ? D ILE 46  
182 1 Y 1 D GLY 26  ? D GLY 47  
183 1 Y 1 D GLY 27  ? D GLY 48  
184 1 Y 1 D GLU 28  ? D GLU 49  
185 1 Y 1 D TRP 29  ? D TRP 50  
186 1 Y 1 D VAL 30  ? D VAL 51  
187 1 Y 1 D ALA 31  ? D ALA 52  
188 1 Y 1 D PRO 32  ? D PRO 53  
189 1 Y 1 D VAL 33  ? D VAL 54  
190 1 Y 1 D SER 34  ? D SER 55  
191 1 Y 1 D GLY 35  ? D GLY 56  
192 1 Y 1 D ARG 36  ? D ARG 57  
193 1 Y 1 D TYR 37  ? D TYR 58  
194 1 Y 1 D PHE 38  ? D PHE 59  
195 1 Y 1 D THR 39  ? D THR 60  
196 1 Y 1 D ASN 40  ? D ASN 61  
197 1 Y 1 D THR 41  ? D THR 62  
198 1 Y 1 D THR 42  ? D THR 63  
199 1 Y 1 D PRO 43  ? D PRO 64  
200 1 Y 1 D ILE 44  ? D ILE 65  
201 1 Y 1 D THR 45  ? D THR 66  
202 1 Y 1 D GLY 46  ? D GLY 67  
203 1 Y 1 D ALA 47  ? D ALA 68  
204 1 Y 1 D GLU 48  ? D GLU 69  
205 1 Y 1 D ILE 49  ? D ILE 70  
206 1 Y 1 D GLY 50  ? D GLY 71  
207 1 Y 1 D GLN 51  ? D GLN 72  
208 1 Y 1 D ILE 52  ? D ILE 73  
209 1 Y 1 D ALA 53  ? D ALA 74  
210 1 Y 1 D ARG 54  ? D ARG 75  
211 1 Y 1 D SER 55  ? D SER 76  
212 1 Y 1 D GLU 56  ? D GLU 77  
213 1 Y 1 D ALA 57  ? D ALA 78  
214 1 Y 1 D GLU 98  ? D GLU 119 
215 1 Y 1 D LEU 99  ? D LEU 120 
216 1 Y 1 D LEU 100 ? D LEU 121 
217 1 Y 1 D ALA 101 ? D ALA 122 
218 1 Y 1 D THR 102 ? D THR 123 
219 1 Y 1 D ALA 103 ? D ALA 124 
220 1 Y 1 D GLU 104 ? D GLU 125 
221 1 Y 1 D THR 105 ? D THR 126 
222 1 Y 1 D TRP 106 ? D TRP 127 
223 1 Y 1 D ASP 107 ? D ASP 128 
224 1 Y 1 D ASN 108 ? D ASN 129 
225 1 Y 1 D GLY 109 ? D GLY 130 
226 1 Y 1 D LYS 110 ? D LYS 131 
227 1 Y 1 D PRO 111 ? D PRO 132 
228 1 Y 1 D ILE 112 ? D ILE 133 
229 1 Y 1 D ARG 113 ? D ARG 134 
230 1 Y 1 D GLU 114 ? D GLU 135 
231 1 Y 1 D THR 115 ? D THR 136 
232 1 Y 1 D MET 116 ? D MET 137 
233 1 Y 1 D ALA 117 ? D ALA 138 
234 1 Y 1 D ILE 163 ? D ILE 184 
235 1 Y 1 D ILE 164 ? D ILE 185 
236 1 Y 1 D PRO 165 ? D PRO 186 
237 1 Y 1 D TRP 166 ? D TRP 187 
238 1 Y 1 D ASN 167 ? D ASN 188 
239 1 Y 1 D PHE 168 ? D PHE 189 
240 1 Y 1 D LYS 190 ? D LYS 211 
241 1 Y 1 D PRO 191 ? D PRO 212 
242 1 Y 1 D ALA 192 ? D ALA 213 
243 1 Y 1 D GLU 193 ? D GLU 214 
244 1 Y 1 D GLN 194 ? D GLN 215 
245 1 Y 1 D THR 195 ? D THR 216 
246 1 Y 1 D PRO 196 ? D PRO 217 
247 1 Y 1 D ALA 197 ? D ALA 218 
248 1 Y 1 D GLY 198 ? D GLY 219 
249 1 Y 1 D ILE 217 ? D ILE 238 
250 1 Y 1 D VAL 218 ? D VAL 239 
251 1 Y 1 D ASN 219 ? D ASN 240 
252 1 Y 1 D GLY 220 ? D GLY 241 
253 1 Y 1 D PHE 221 ? D PHE 242 
254 1 Y 1 D GLY 222 ? D GLY 243 
255 1 Y 1 D LEU 223 ? D LEU 244 
256 1 Y 1 D GLU 224 ? D GLU 245 
257 1 Y 1 D ALA 225 ? D ALA 246 
258 1 Y 1 D GLY 226 ? D GLY 247 
259 1 Y 1 D LYS 227 ? D LYS 248 
260 1 Y 1 D PRO 228 ? D PRO 249 
261 1 Y 1 D LEU 229 ? D LEU 250 
262 1 Y 1 D ALA 230 ? D ALA 251 
263 1 Y 1 D SER 231 ? D SER 252 
264 1 Y 1 D SER 232 ? D SER 253 
265 1 Y 1 D ASN 233 ? D ASN 254 
266 1 Y 1 D ARG 234 ? D ARG 255 
267 1 Y 1 D ILE 235 ? D ILE 256 
268 1 Y 1 D ALA 236 ? D ALA 257 
269 1 Y 1 D LYS 237 ? D LYS 258 
270 1 Y 1 D ILE 238 ? D ILE 259 
271 1 Y 1 D ALA 239 ? D ALA 260 
272 1 Y 1 D PHE 240 ? D PHE 261 
273 1 Y 1 D THR 241 ? D THR 262 
274 1 Y 1 D GLY 242 ? D GLY 263 
275 1 Y 1 D GLU 243 ? D GLU 264 
276 1 Y 1 D THR 244 ? D THR 265 
277 1 Y 1 D THR 245 ? D THR 266 
278 1 Y 1 D THR 246 ? D THR 267 
279 1 Y 1 D GLY 247 ? D GLY 268 
280 1 Y 1 D ARG 248 ? D ARG 269 
281 1 Y 1 D LEU 249 ? D LEU 270 
282 1 Y 1 D ILE 250 ? D ILE 271 
283 1 Y 1 D MET 251 ? D MET 272 
284 1 Y 1 D GLN 252 ? D GLN 273 
285 1 Y 1 D TYR 253 ? D TYR 274 
286 1 Y 1 D ALA 254 ? D ALA 275 
287 1 Y 1 D SER 255 ? D SER 276 
288 1 Y 1 D GLU 256 ? D GLU 277 
289 1 Y 1 D ASN 257 ? D ASN 278 
290 1 Y 1 D LEU 258 ? D LEU 279 
291 1 Y 1 D ILE 259 ? D ILE 280 
292 1 Y 1 D PRO 260 ? D PRO 281 
293 1 Y 1 D VAL 261 ? D VAL 282 
294 1 Y 1 D THR 262 ? D THR 283 
295 1 Y 1 D LEU 263 ? D LEU 284 
296 1 Y 1 D GLU 264 ? D GLU 285 
297 1 Y 1 D LEU 265 ? D LEU 286 
298 1 Y 1 D GLY 266 ? D GLY 287 
299 1 Y 1 D GLY 267 ? D GLY 288 
300 1 Y 1 D LYS 268 ? D LYS 289 
301 1 Y 1 D VAL 277 ? D VAL 298 
302 1 Y 1 D ALA 278 ? D ALA 299 
303 1 Y 1 D ARG 279 ? D ARG 300 
304 1 Y 1 D GLU 280 ? D GLU 301 
305 1 Y 1 D ASP 281 ? D ASP 302 
306 1 Y 1 D ASP 282 ? D ASP 303 
307 1 Y 1 D ASP 283 ? D ASP 304 
308 1 Y 1 D PHE 284 ? D PHE 305 
309 1 Y 1 D PHE 285 ? D PHE 306 
310 1 Y 1 D ASP 286 ? D ASP 307 
311 1 Y 1 D LYS 287 ? D LYS 308 
312 1 Y 1 D ALA 288 ? D ALA 309 
313 1 Y 1 D LEU 289 ? D LEU 310 
314 1 Y 1 D GLU 290 ? D GLU 311 
315 1 Y 1 D GLY 291 ? D GLY 312 
316 1 Y 1 D PHE 292 ? D PHE 313 
317 1 Y 1 D THR 293 ? D THR 314 
318 1 Y 1 D MET 294 ? D MET 315 
319 1 Y 1 D PHE 295 ? D PHE 316 
320 1 Y 1 D ALA 296 ? D ALA 317 
321 1 Y 1 D LEU 297 ? D LEU 318 
322 1 Y 1 D ASN 298 ? D ASN 319 
323 1 Y 1 D GLN 299 ? D GLN 320 
324 1 Y 1 D GLY 300 ? D GLY 321 
325 1 Y 1 D GLU 301 ? D GLU 322 
326 1 Y 1 D VAL 302 ? D VAL 323 
327 1 Y 1 D CYS 303 ? D CYS 324 
328 1 Y 1 D THR 304 ? D THR 325 
329 1 Y 1 D CYS 305 ? D CYS 326 
330 1 Y 1 D PRO 306 ? D PRO 327 
331 1 Y 1 D SER 307 ? D SER 328 
332 1 Y 1 D GLU 313 ? D GLU 334 
333 1 Y 1 D SER 314 ? D SER 335 
334 1 Y 1 D ILE 315 ? D ILE 336 
335 1 Y 1 D TYR 316 ? D TYR 337 
336 1 Y 1 D ASP 317 ? D ASP 338 
337 1 Y 1 D LYS 318 ? D LYS 339 
338 1 Y 1 D PHE 319 ? D PHE 340 
339 1 Y 1 D MET 320 ? D MET 341 
340 1 Y 1 D GLU 321 ? D GLU 342 
341 1 Y 1 D ARG 322 ? D ARG 343 
342 1 Y 1 D ALA 323 ? D ALA 344 
343 1 Y 1 D VAL 324 ? D VAL 345 
344 1 Y 1 D GLN 325 ? D GLN 346 
345 1 Y 1 D ARG 326 ? D ARG 347 
346 1 Y 1 D VAL 327 ? D VAL 348 
347 1 Y 1 D GLN 328 ? D GLN 349 
348 1 Y 1 D ALA 329 ? D ALA 350 
349 1 Y 1 D ILE 330 ? D ILE 351 
350 1 Y 1 D LYS 331 ? D LYS 352 
351 1 Y 1 D GLN 332 ? D GLN 353 
352 1 Y 1 D GLY 333 ? D GLY 354 
353 1 Y 1 D ASP 334 ? D ASP 355 
354 1 Y 1 D PRO 335 ? D PRO 356 
355 1 Y 1 D ARG 336 ? D ARG 357 
356 1 Y 1 D GLU 337 ? D GLU 358 
357 1 Y 1 D SER 338 ? D SER 359 
358 1 Y 1 D ASP 339 ? D ASP 360 
359 1 Y 1 D THR 340 ? D THR 361 
360 1 Y 1 D MET 341 ? D MET 362 
361 1 Y 1 D ILE 342 ? D ILE 363 
362 1 Y 1 D GLY 343 ? D GLY 364 
363 1 Y 1 D ALA 344 ? D ALA 365 
364 1 Y 1 D GLN 345 ? D GLN 366 
365 1 Y 1 D ALA 346 ? D ALA 367 
366 1 Y 1 D SER 347 ? D SER 368 
367 1 Y 1 D SER 348 ? D SER 369 
368 1 Y 1 D GLU 349 ? D GLU 370 
369 1 Y 1 D GLN 350 ? D GLN 371 
370 1 Y 1 D LYS 351 ? D LYS 372 
371 1 Y 1 D GLU 352 ? D GLU 373 
372 1 Y 1 D LYS 353 ? D LYS 374 
373 1 Y 1 D ILE 354 ? D ILE 375 
374 1 Y 1 D LEU 355 ? D LEU 376 
375 1 Y 1 D SER 356 ? D SER 377 
376 1 Y 1 D TYR 357 ? D TYR 378 
377 1 Y 1 D LEU 358 ? D LEU 379 
378 1 Y 1 D ASP 359 ? D ASP 380 
379 1 Y 1 D ILE 360 ? D ILE 381 
380 1 Y 1 D GLY 361 ? D GLY 382 
381 1 Y 1 D LYS 362 ? D LYS 383 
382 1 Y 1 D LYS 363 ? D LYS 384 
383 1 Y 1 D GLU 364 ? D GLU 385 
384 1 Y 1 D GLY 365 ? D GLY 386 
385 1 Y 1 D ALA 366 ? D ALA 387 
386 1 Y 1 D GLU 367 ? D GLU 388 
387 1 Y 1 D VAL 368 ? D VAL 389 
388 1 Y 1 D LEU 369 ? D LEU 390 
389 1 Y 1 D THR 370 ? D THR 391 
390 1 Y 1 D GLY 371 ? D GLY 392 
391 1 Y 1 D GLY 372 ? D GLY 393 
392 1 Y 1 D LYS 373 ? D LYS 394 
393 1 Y 1 D ALA 374 ? D ALA 395 
394 1 Y 1 D ALA 375 ? D ALA 396 
395 1 Y 1 D ASP 376 ? D ASP 397 
396 1 Y 1 D LEU 377 ? D LEU 398 
397 1 Y 1 D GLY 378 ? D GLY 399 
398 1 Y 1 D GLY 379 ? D GLY 400 
399 1 Y 1 D GLU 380 ? D GLU 401 
400 1 Y 1 D LEU 381 ? D LEU 402 
401 1 Y 1 D SER 382 ? D SER 403 
402 1 Y 1 D GLY 383 ? D GLY 404 
403 1 Y 1 D GLY 384 ? D GLY 405 
404 1 Y 1 D TYR 385 ? D TYR 406 
405 1 Y 1 D TYR 386 ? D TYR 407 
406 1 Y 1 D ILE 387 ? D ILE 408 
407 1 Y 1 D GLU 388 ? D GLU 409 
408 1 Y 1 D PRO 389 ? D PRO 410 
409 1 Y 1 D THR 390 ? D THR 411 
410 1 Y 1 D ILE 391 ? D ILE 412 
411 1 Y 1 D PHE 392 ? D PHE 413 
412 1 Y 1 D ARG 393 ? D ARG 414 
413 1 Y 1 D GLY 394 ? D GLY 415 
414 1 Y 1 D ASN 395 ? D ASN 416 
415 1 Y 1 D ASN 396 ? D ASN 417 
416 1 Y 1 D LYS 397 ? D LYS 418 
417 1 Y 1 D MET 398 ? D MET 419 
418 1 Y 1 D ARG 399 ? D ARG 420 
419 1 Y 1 D ILE 400 ? D ILE 421 
420 1 Y 1 D PHE 401 ? D PHE 422 
421 1 Y 1 D GLN 402 ? D GLN 423 
422 1 Y 1 D GLU 403 ? D GLU 424 
423 1 Y 1 D GLU 404 ? D GLU 425 
424 1 Y 1 D ILE 405 ? D ILE 426 
425 1 Y 1 D PHE 406 ? D PHE 427 
426 1 Y 1 D GLY 407 ? D GLY 428 
427 1 Y 1 D PRO 408 ? D PRO 429 
428 1 Y 1 D VAL 409 ? D VAL 430 
429 1 Y 1 D VAL 410 ? D VAL 431 
430 1 Y 1 D SER 411 ? D SER 432 
431 1 Y 1 D ASN 426 ? D ASN 447 
432 1 Y 1 D ASP 427 ? D ASP 448 
433 1 Y 1 D THR 428 ? D THR 449 
434 1 Y 1 D LEU 429 ? D LEU 450 
435 1 Y 1 D TYR 430 ? D TYR 451 
436 1 Y 1 D GLY 431 ? D GLY 452 
437 1 Y 1 D LEU 432 ? D LEU 453 
438 1 Y 1 D HIS 462 ? D HIS 483 
439 1 Y 1 D ALA 463 ? D ALA 484 
440 1 Y 1 D TYR 464 ? D TYR 485 
441 1 Y 1 D PRO 465 ? D PRO 486 
442 1 Y 1 D ALA 466 ? D ALA 487 
443 1 Y 1 D HIS 467 ? D HIS 488 
444 1 Y 1 D ALA 468 ? D ALA 489 
445 1 Y 1 D ALA 469 ? D ALA 490 
446 1 Y 1 D PHE 470 ? D PHE 491 
447 1 Y 1 D GLY 471 ? D GLY 492 
448 1 Y 1 D GLY 472 ? D GLY 493 
449 1 Y 1 D TYR 473 ? D TYR 494 
450 1 Y 1 D LYS 474 ? D LYS 495 
451 1 Y 1 D GLN 475 ? D GLN 496 
452 1 Y 1 D SER 476 ? D SER 497 
453 1 Y 1 D GLY 477 ? D GLY 498 
454 1 Y 1 D ILE 478 ? D ILE 499 
455 1 Y 1 D GLY 479 ? D GLY 500 
456 1 Y 1 D ARG 480 ? D ARG 501 
457 1 Y 1 D GLU 481 ? D GLU 502 
458 1 Y 1 D LEU 505 ? D LEU 526 
459 1 Y 1 D GLY 506 ? D GLY 527 
460 1 Y 1 D PHE 507 ? D PHE 528 
461 1 Y 1 D PHE 508 ? D PHE 529 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
K   K    K N N 180 
LEU N    N N N 181 
LEU CA   C N S 182 
LEU C    C N N 183 
LEU O    O N N 184 
LEU CB   C N N 185 
LEU CG   C N N 186 
LEU CD1  C N N 187 
LEU CD2  C N N 188 
LEU OXT  O N N 189 
LEU H    H N N 190 
LEU H2   H N N 191 
LEU HA   H N N 192 
LEU HB2  H N N 193 
LEU HB3  H N N 194 
LEU HG   H N N 195 
LEU HD11 H N N 196 
LEU HD12 H N N 197 
LEU HD13 H N N 198 
LEU HD21 H N N 199 
LEU HD22 H N N 200 
LEU HD23 H N N 201 
LEU HXT  H N N 202 
LYS N    N N N 203 
LYS CA   C N S 204 
LYS C    C N N 205 
LYS O    O N N 206 
LYS CB   C N N 207 
LYS CG   C N N 208 
LYS CD   C N N 209 
LYS CE   C N N 210 
LYS NZ   N N N 211 
LYS OXT  O N N 212 
LYS H    H N N 213 
LYS H2   H N N 214 
LYS HA   H N N 215 
LYS HB2  H N N 216 
LYS HB3  H N N 217 
LYS HG2  H N N 218 
LYS HG3  H N N 219 
LYS HD2  H N N 220 
LYS HD3  H N N 221 
LYS HE2  H N N 222 
LYS HE3  H N N 223 
LYS HZ1  H N N 224 
LYS HZ2  H N N 225 
LYS HZ3  H N N 226 
LYS HXT  H N N 227 
MET N    N N N 228 
MET CA   C N S 229 
MET C    C N N 230 
MET O    O N N 231 
MET CB   C N N 232 
MET CG   C N N 233 
MET SD   S N N 234 
MET CE   C N N 235 
MET OXT  O N N 236 
MET H    H N N 237 
MET H2   H N N 238 
MET HA   H N N 239 
MET HB2  H N N 240 
MET HB3  H N N 241 
MET HG2  H N N 242 
MET HG3  H N N 243 
MET HE1  H N N 244 
MET HE2  H N N 245 
MET HE3  H N N 246 
MET HXT  H N N 247 
PHE N    N N N 248 
PHE CA   C N S 249 
PHE C    C N N 250 
PHE O    O N N 251 
PHE CB   C N N 252 
PHE CG   C Y N 253 
PHE CD1  C Y N 254 
PHE CD2  C Y N 255 
PHE CE1  C Y N 256 
PHE CE2  C Y N 257 
PHE CZ   C Y N 258 
PHE OXT  O N N 259 
PHE H    H N N 260 
PHE H2   H N N 261 
PHE HA   H N N 262 
PHE HB2  H N N 263 
PHE HB3  H N N 264 
PHE HD1  H N N 265 
PHE HD2  H N N 266 
PHE HE1  H N N 267 
PHE HE2  H N N 268 
PHE HZ   H N N 269 
PHE HXT  H N N 270 
PRO N    N N N 271 
PRO CA   C N S 272 
PRO C    C N N 273 
PRO O    O N N 274 
PRO CB   C N N 275 
PRO CG   C N N 276 
PRO CD   C N N 277 
PRO OXT  O N N 278 
PRO H    H N N 279 
PRO HA   H N N 280 
PRO HB2  H N N 281 
PRO HB3  H N N 282 
PRO HG2  H N N 283 
PRO HG3  H N N 284 
PRO HD2  H N N 285 
PRO HD3  H N N 286 
PRO HXT  H N N 287 
SER N    N N N 288 
SER CA   C N S 289 
SER C    C N N 290 
SER O    O N N 291 
SER CB   C N N 292 
SER OG   O N N 293 
SER OXT  O N N 294 
SER H    H N N 295 
SER H2   H N N 296 
SER HA   H N N 297 
SER HB2  H N N 298 
SER HB3  H N N 299 
SER HG   H N N 300 
SER HXT  H N N 301 
THR N    N N N 302 
THR CA   C N S 303 
THR C    C N N 304 
THR O    O N N 305 
THR CB   C N R 306 
THR OG1  O N N 307 
THR CG2  C N N 308 
THR OXT  O N N 309 
THR H    H N N 310 
THR H2   H N N 311 
THR HA   H N N 312 
THR HB   H N N 313 
THR HG1  H N N 314 
THR HG21 H N N 315 
THR HG22 H N N 316 
THR HG23 H N N 317 
THR HXT  H N N 318 
TRP N    N N N 319 
TRP CA   C N S 320 
TRP C    C N N 321 
TRP O    O N N 322 
TRP CB   C N N 323 
TRP CG   C Y N 324 
TRP CD1  C Y N 325 
TRP CD2  C Y N 326 
TRP NE1  N Y N 327 
TRP CE2  C Y N 328 
TRP CE3  C Y N 329 
TRP CZ2  C Y N 330 
TRP CZ3  C Y N 331 
TRP CH2  C Y N 332 
TRP OXT  O N N 333 
TRP H    H N N 334 
TRP H2   H N N 335 
TRP HA   H N N 336 
TRP HB2  H N N 337 
TRP HB3  H N N 338 
TRP HD1  H N N 339 
TRP HE1  H N N 340 
TRP HE3  H N N 341 
TRP HZ2  H N N 342 
TRP HZ3  H N N 343 
TRP HH2  H N N 344 
TRP HXT  H N N 345 
TYR N    N N N 346 
TYR CA   C N S 347 
TYR C    C N N 348 
TYR O    O N N 349 
TYR CB   C N N 350 
TYR CG   C Y N 351 
TYR CD1  C Y N 352 
TYR CD2  C Y N 353 
TYR CE1  C Y N 354 
TYR CE2  C Y N 355 
TYR CZ   C Y N 356 
TYR OH   O N N 357 
TYR OXT  O N N 358 
TYR H    H N N 359 
TYR H2   H N N 360 
TYR HA   H N N 361 
TYR HB2  H N N 362 
TYR HB3  H N N 363 
TYR HD1  H N N 364 
TYR HD2  H N N 365 
TYR HE1  H N N 366 
TYR HE2  H N N 367 
TYR HH   H N N 368 
TYR HXT  H N N 369 
VAL N    N N N 370 
VAL CA   C N S 371 
VAL C    C N N 372 
VAL O    O N N 373 
VAL CB   C N N 374 
VAL CG1  C N N 375 
VAL CG2  C N N 376 
VAL OXT  O N N 377 
VAL H    H N N 378 
VAL H2   H N N 379 
VAL HA   H N N 380 
VAL HB   H N N 381 
VAL HG11 H N N 382 
VAL HG12 H N N 383 
VAL HG13 H N N 384 
VAL HG21 H N N 385 
VAL HG22 H N N 386 
VAL HG23 H N N 387 
VAL HXT  H N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-05 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           9FM9 
_em_admin.last_update        2025-06-11 
_em_admin.map_release_date   2025-06-11 
_em_admin.title              'Aldehyde dehydrogenase' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          266 
_em_entity_assembly_naturalsource.organism             'Paracoccus denitrificans' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           0.3 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Chinese Scholarship Council' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           CSC202207720003 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9FM9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
K 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ARG A 1 31  ? 97.794  113.731 60.867  1.00 13.06 ? 10   ARG A N   1 
ATOM   2     C CA  . ARG A 1 31  ? 97.562  113.952 62.290  1.00 13.06 ? 10   ARG A CA  1 
ATOM   3     C C   . ARG A 1 31  ? 96.085  114.185 62.593  1.00 13.06 ? 10   ARG A C   1 
ATOM   4     O O   . ARG A 1 31  ? 95.487  115.155 62.127  1.00 13.06 ? 10   ARG A O   1 
ATOM   5     C CB  . ARG A 1 31  ? 98.398  115.135 62.789  1.00 13.06 ? 10   ARG A CB  1 
ATOM   6     C CG  . ARG A 1 31  ? 98.231  115.459 64.266  1.00 13.06 ? 10   ARG A CG  1 
ATOM   7     C CD  . ARG A 1 31  ? 98.721  114.319 65.142  1.00 13.06 ? 10   ARG A CD  1 
ATOM   8     N NE  . ARG A 1 31  ? 97.632  113.419 65.509  1.00 13.06 ? 10   ARG A NE  1 
ATOM   9     C CZ  . ARG A 1 31  ? 97.801  112.195 65.995  1.00 13.06 ? 10   ARG A CZ  1 
ATOM   10    N NH1 . ARG A 1 31  ? 99.021  111.709 66.157  1.00 13.06 ? 10   ARG A NH1 1 
ATOM   11    N NH2 . ARG A 1 31  ? 96.750  111.450 66.303  1.00 13.06 ? 10   ARG A NH2 1 
ATOM   12    N N   . GLY A 1 32  ? 95.508  113.286 63.372  1.00 15.26 ? 11   GLY A N   1 
ATOM   13    C CA  . GLY A 1 32  ? 94.124  113.388 63.781  1.00 15.26 ? 11   GLY A CA  1 
ATOM   14    C C   . GLY A 1 32  ? 93.686  112.148 64.519  1.00 15.26 ? 11   GLY A C   1 
ATOM   15    O O   . GLY A 1 32  ? 94.337  111.103 64.487  1.00 15.26 ? 11   GLY A O   1 
ATOM   16    N N   . VAL A 1 33  ? 92.551  112.273 65.208  1.00 15.31 ? 12   VAL A N   1 
ATOM   17    C CA  . VAL A 1 33  ? 92.017  111.143 65.963  1.00 15.31 ? 12   VAL A CA  1 
ATOM   18    C C   . VAL A 1 33  ? 91.599  110.022 65.022  1.00 15.31 ? 12   VAL A C   1 
ATOM   19    O O   . VAL A 1 33  ? 91.837  108.840 65.296  1.00 15.31 ? 12   VAL A O   1 
ATOM   20    C CB  . VAL A 1 33  ? 90.851  111.599 66.860  1.00 15.31 ? 12   VAL A CB  1 
ATOM   21    C CG1 . VAL A 1 33  ? 90.221  110.410 67.557  1.00 15.31 ? 12   VAL A CG1 1 
ATOM   22    C CG2 . VAL A 1 33  ? 91.334  112.608 67.887  1.00 15.31 ? 12   VAL A CG2 1 
ATOM   23    N N   . ASN A 1 34  ? 90.985  110.372 63.895  1.00 17.90 ? 13   ASN A N   1 
ATOM   24    C CA  . ASN A 1 34  ? 90.469  109.387 62.954  1.00 17.90 ? 13   ASN A CA  1 
ATOM   25    C C   . ASN A 1 34  ? 91.515  108.897 61.962  1.00 17.90 ? 13   ASN A C   1 
ATOM   26    O O   . ASN A 1 34  ? 91.210  108.017 61.150  1.00 17.90 ? 13   ASN A O   1 
ATOM   27    C CB  . ASN A 1 34  ? 89.268  109.962 62.199  1.00 17.90 ? 13   ASN A CB  1 
ATOM   28    C CG  . ASN A 1 34  ? 88.090  110.240 63.110  1.00 17.90 ? 13   ASN A CG  1 
ATOM   29    O OD1 . ASN A 1 34  ? 88.264  110.513 64.297  1.00 17.90 ? 13   ASN A OD1 1 
ATOM   30    N ND2 . ASN A 1 34  ? 86.883  110.164 62.563  1.00 17.90 ? 13   ASN A ND2 1 
ATOM   31    N N   . ALA A 1 35  ? 92.727  109.435 62.003  1.00 18.48 ? 14   ALA A N   1 
ATOM   32    C CA  . ALA A 1 35  ? 93.827  108.946 61.187  1.00 18.48 ? 14   ALA A CA  1 
ATOM   33    C C   . ALA A 1 35  ? 94.707  108.009 62.005  1.00 18.48 ? 14   ALA A C   1 
ATOM   34    O O   . ALA A 1 35  ? 94.732  108.060 63.237  1.00 18.48 ? 14   ALA A O   1 
ATOM   35    C CB  . ALA A 1 35  ? 94.661  110.104 60.637  1.00 18.48 ? 14   ALA A CB  1 
ATOM   36    N N   . LEU A 1 36  ? 95.432  107.149 61.301  1.00 18.32 ? 15   LEU A N   1 
ATOM   37    C CA  . LEU A 1 36  ? 96.236  106.136 61.966  1.00 18.32 ? 15   LEU A CA  1 
ATOM   38    C C   . LEU A 1 36  ? 97.355  106.793 62.767  1.00 18.32 ? 15   LEU A C   1 
ATOM   39    O O   . LEU A 1 36  ? 98.121  107.594 62.215  1.00 18.32 ? 15   LEU A O   1 
ATOM   40    C CB  . LEU A 1 36  ? 96.820  105.167 60.943  1.00 18.32 ? 15   LEU A CB  1 
ATOM   41    C CG  . LEU A 1 36  ? 97.331  103.828 61.473  1.00 18.32 ? 15   LEU A CG  1 
ATOM   42    C CD1 . LEU A 1 36  ? 96.256  103.129 62.280  1.00 18.32 ? 15   LEU A CD1 1 
ATOM   43    C CD2 . LEU A 1 36  ? 97.809  102.947 60.325  1.00 18.32 ? 15   LEU A CD2 1 
ATOM   44    N N   . PRO A 1 37  ? 97.481  106.495 64.059  1.00 16.95 ? 16   PRO A N   1 
ATOM   45    C CA  . PRO A 1 37  ? 98.567  107.063 64.873  1.00 16.95 ? 16   PRO A CA  1 
ATOM   46    C C   . PRO A 1 37  ? 99.810  106.193 64.998  1.00 16.95 ? 16   PRO A C   1 
ATOM   47    O O   . PRO A 1 37  ? 100.776 106.636 65.627  1.00 16.95 ? 16   PRO A O   1 
ATOM   48    C CB  . PRO A 1 37  ? 97.886  107.207 66.235  1.00 16.95 ? 16   PRO A CB  1 
ATOM   49    C CG  . PRO A 1 37  ? 96.978  106.042 66.288  1.00 16.95 ? 16   PRO A CG  1 
ATOM   50    C CD  . PRO A 1 37  ? 96.506  105.769 64.887  1.00 16.95 ? 16   PRO A CD  1 
ATOM   51    N N   . PHE A 1 38  ? 99.810  104.989 64.442  1.00 16.41 ? 17   PHE A N   1 
ATOM   52    C CA  . PHE A 1 38  ? 100.951 104.098 64.521  1.00 16.41 ? 17   PHE A CA  1 
ATOM   53    C C   . PHE A 1 38  ? 101.716 104.100 63.204  1.00 16.41 ? 17   PHE A C   1 
ATOM   54    O O   . PHE A 1 38  ? 101.422 104.867 62.284  1.00 16.41 ? 17   PHE A O   1 
ATOM   55    C CB  . PHE A 1 38  ? 100.509 102.679 64.870  1.00 16.41 ? 17   PHE A CB  1 
ATOM   56    C CG  . PHE A 1 38  ? 99.520  102.609 65.982  1.00 16.41 ? 17   PHE A CG  1 
ATOM   57    C CD1 . PHE A 1 38  ? 99.884  102.932 67.270  1.00 16.41 ? 17   PHE A CD1 1 
ATOM   58    C CD2 . PHE A 1 38  ? 98.226  102.207 65.738  1.00 16.41 ? 17   PHE A CD2 1 
ATOM   59    C CE1 . PHE A 1 38  ? 98.972  102.861 68.288  1.00 16.41 ? 17   PHE A CE1 1 
ATOM   60    C CE2 . PHE A 1 38  ? 97.315  102.136 66.751  1.00 16.41 ? 17   PHE A CE2 1 
ATOM   61    C CZ  . PHE A 1 38  ? 97.688  102.466 68.027  1.00 16.41 ? 17   PHE A CZ  1 
ATOM   62    N N   . GLU A 1 39  ? 102.716 103.228 63.116  1.00 25.96 ? 18   GLU A N   1 
ATOM   63    C CA  . GLU A 1 39  ? 103.366 102.894 61.861  1.00 25.96 ? 18   GLU A CA  1 
ATOM   64    C C   . GLU A 1 39  ? 103.712 101.414 61.899  1.00 25.96 ? 18   GLU A C   1 
ATOM   65    O O   . GLU A 1 39  ? 103.551 100.744 62.922  1.00 25.96 ? 18   GLU A O   1 
ATOM   66    C CB  . GLU A 1 39  ? 104.619 103.742 61.616  1.00 25.96 ? 18   GLU A CB  1 
ATOM   67    C CG  . GLU A 1 39  ? 105.738 103.477 62.589  1.00 25.96 ? 18   GLU A CG  1 
ATOM   68    C CD  . GLU A 1 39  ? 106.719 104.621 62.689  1.00 25.96 ? 18   GLU A CD  1 
ATOM   69    O OE1 . GLU A 1 39  ? 107.399 104.730 63.732  1.00 25.96 ? 18   GLU A OE1 1 
ATOM   70    O OE2 . GLU A 1 39  ? 106.813 105.412 61.728  1.00 25.96 ? 18   GLU A OE2 1 
ATOM   71    N N   . GLU A 1 40  ? 104.184 100.899 60.774  1.00 28.50 ? 19   GLU A N   1 
ATOM   72    C CA  . GLU A 1 40  ? 104.507 99.486  60.668  1.00 28.50 ? 19   GLU A CA  1 
ATOM   73    C C   . GLU A 1 40  ? 105.918 99.213  61.171  1.00 28.50 ? 19   GLU A C   1 
ATOM   74    O O   . GLU A 1 40  ? 106.792 100.082 61.133  1.00 28.50 ? 19   GLU A O   1 
ATOM   75    C CB  . GLU A 1 40  ? 104.364 99.011  59.225  1.00 28.50 ? 19   GLU A CB  1 
ATOM   76    C CG  . GLU A 1 40  ? 102.935 99.046  58.727  1.00 28.50 ? 19   GLU A CG  1 
ATOM   77    C CD  . GLU A 1 40  ? 102.811 98.634  57.279  1.00 28.50 ? 19   GLU A CD  1 
ATOM   78    O OE1 . GLU A 1 40  ? 103.855 98.444  56.621  1.00 28.50 ? 19   GLU A OE1 1 
ATOM   79    O OE2 . GLU A 1 40  ? 101.666 98.495  56.801  1.00 28.50 ? 19   GLU A OE2 1 
ATOM   80    N N   . ARG A 1 41  ? 106.125 97.987  61.655  1.00 26.69 ? 20   ARG A N   1 
ATOM   81    C CA  . ARG A 1 41  ? 107.418 97.511  62.142  1.00 26.69 ? 20   ARG A CA  1 
ATOM   82    C C   . ARG A 1 41  ? 107.907 98.339  63.337  1.00 26.69 ? 20   ARG A C   1 
ATOM   83    O O   . ARG A 1 41  ? 108.937 99.012  63.297  1.00 26.69 ? 20   ARG A O   1 
ATOM   84    C CB  . ARG A 1 41  ? 108.455 97.494  61.013  1.00 26.69 ? 20   ARG A CB  1 
ATOM   85    C CG  . ARG A 1 41  ? 108.357 96.283  60.098  1.00 26.69 ? 20   ARG A CG  1 
ATOM   86    C CD  . ARG A 1 41  ? 109.430 95.262  60.417  1.00 26.69 ? 20   ARG A CD  1 
ATOM   87    N NE  . ARG A 1 41  ? 109.363 94.110  59.525  1.00 26.69 ? 20   ARG A NE  1 
ATOM   88    C CZ  . ARG A 1 41  ? 110.284 93.807  58.615  1.00 26.69 ? 20   ARG A CZ  1 
ATOM   89    N NH1 . ARG A 1 41  ? 111.357 94.572  58.470  1.00 26.69 ? 20   ARG A NH1 1 
ATOM   90    N NH2 . ARG A 1 41  ? 110.134 92.736  57.852  1.00 26.69 ? 20   ARG A NH2 1 
ATOM   91    N N   . TYR A 1 42  ? 107.114 98.278  64.405  1.00 22.25 ? 21   TYR A N   1 
ATOM   92    C CA  . TYR A 1 42  ? 107.599 98.547  65.759  1.00 22.25 ? 21   TYR A CA  1 
ATOM   93    C C   . TYR A 1 42  ? 108.513 97.424  66.223  1.00 22.25 ? 21   TYR A C   1 
ATOM   94    O O   . TYR A 1 42  ? 108.055 96.391  66.712  1.00 22.25 ? 21   TYR A O   1 
ATOM   95    C CB  . TYR A 1 42  ? 106.435 98.743  66.721  1.00 22.25 ? 21   TYR A CB  1 
ATOM   96    C CG  . TYR A 1 42  ? 105.663 100.016 66.514  1.00 22.25 ? 21   TYR A CG  1 
ATOM   97    C CD1 . TYR A 1 42  ? 106.193 101.040 65.758  1.00 22.25 ? 21   TYR A CD1 1 
ATOM   98    C CD2 . TYR A 1 42  ? 104.399 100.189 67.055  1.00 22.25 ? 21   TYR A CD2 1 
ATOM   99    C CE1 . TYR A 1 42  ? 105.519 102.212 65.588  1.00 22.25 ? 21   TYR A CE1 1 
ATOM   100   C CE2 . TYR A 1 42  ? 103.708 101.363 66.876  1.00 22.25 ? 21   TYR A CE2 1 
ATOM   101   C CZ  . TYR A 1 42  ? 104.273 102.367 66.133  1.00 22.25 ? 21   TYR A CZ  1 
ATOM   102   O OH  . TYR A 1 42  ? 103.600 103.542 65.938  1.00 22.25 ? 21   TYR A OH  1 
ATOM   103   N N   . ASP A 1 43  ? 109.816 97.642  66.085  1.00 18.23 ? 22   ASP A N   1 
ATOM   104   C CA  . ASP A 1 43  ? 110.824 96.723  66.592  1.00 18.23 ? 22   ASP A CA  1 
ATOM   105   C C   . ASP A 1 43  ? 110.913 96.863  68.112  1.00 18.23 ? 22   ASP A C   1 
ATOM   106   O O   . ASP A 1 43  ? 110.145 97.589  68.746  1.00 18.23 ? 22   ASP A O   1 
ATOM   107   C CB  . ASP A 1 43  ? 112.161 96.989  65.914  1.00 18.23 ? 22   ASP A CB  1 
ATOM   108   C CG  . ASP A 1 43  ? 112.234 96.401  64.520  1.00 18.23 ? 22   ASP A CG  1 
ATOM   109   O OD1 . ASP A 1 43  ? 111.695 95.292  64.316  1.00 18.23 ? 22   ASP A OD1 1 
ATOM   110   O OD2 . ASP A 1 43  ? 112.828 97.045  63.628  1.00 18.23 ? 22   ASP A OD2 1 
ATOM   111   N N   . ASN A 1 44  ? 111.865 96.157  68.714  1.00 12.66 ? 23   ASN A N   1 
ATOM   112   C CA  . ASN A 1 44  ? 112.054 96.206  70.157  1.00 12.66 ? 23   ASN A CA  1 
ATOM   113   C C   . ASN A 1 44  ? 112.816 97.464  70.548  1.00 12.66 ? 23   ASN A C   1 
ATOM   114   O O   . ASN A 1 44  ? 113.822 97.808  69.922  1.00 12.66 ? 23   ASN A O   1 
ATOM   115   C CB  . ASN A 1 44  ? 112.813 94.972  70.634  1.00 12.66 ? 23   ASN A CB  1 
ATOM   116   C CG  . ASN A 1 44  ? 112.075 93.694  70.350  1.00 12.66 ? 23   ASN A CG  1 
ATOM   117   O OD1 . ASN A 1 44  ? 112.015 93.243  69.212  1.00 12.66 ? 23   ASN A OD1 1 
ATOM   118   N ND2 . ASN A 1 44  ? 111.515 93.094  71.386  1.00 12.66 ? 23   ASN A ND2 1 
ATOM   119   N N   . PHE A 1 45  ? 112.340 98.148  71.589  1.00 6.61  ? 24   PHE A N   1 
ATOM   120   C CA  . PHE A 1 45  ? 112.999 99.355  72.086  1.00 6.61  ? 24   PHE A CA  1 
ATOM   121   C C   . PHE A 1 45  ? 113.978 98.950  73.181  1.00 6.61  ? 24   PHE A C   1 
ATOM   122   O O   . PHE A 1 45  ? 113.697 99.028  74.378  1.00 6.61  ? 24   PHE A O   1 
ATOM   123   C CB  . PHE A 1 45  ? 111.975 100.362 72.587  1.00 6.61  ? 24   PHE A CB  1 
ATOM   124   C CG  . PHE A 1 45  ? 112.583 101.606 73.159  1.00 6.61  ? 24   PHE A CG  1 
ATOM   125   C CD1 . PHE A 1 45  ? 113.353 102.441 72.374  1.00 6.61  ? 24   PHE A CD1 1 
ATOM   126   C CD2 . PHE A 1 45  ? 112.388 101.940 74.484  1.00 6.61  ? 24   PHE A CD2 1 
ATOM   127   C CE1 . PHE A 1 45  ? 113.914 103.583 72.901  1.00 6.61  ? 24   PHE A CE1 1 
ATOM   128   C CE2 . PHE A 1 45  ? 112.945 103.081 75.014  1.00 6.61  ? 24   PHE A CE2 1 
ATOM   129   C CZ  . PHE A 1 45  ? 113.707 103.902 74.223  1.00 6.61  ? 24   PHE A CZ  1 
ATOM   130   N N   . ILE A 1 46  ? 115.156 98.509  72.752  1.00 7.78  ? 25   ILE A N   1 
ATOM   131   C CA  . ILE A 1 46  ? 116.155 97.925  73.639  1.00 7.78  ? 25   ILE A CA  1 
ATOM   132   C C   . ILE A 1 46  ? 117.347 98.866  73.724  1.00 7.78  ? 25   ILE A C   1 
ATOM   133   O O   . ILE A 1 46  ? 118.005 99.137  72.713  1.00 7.78  ? 25   ILE A O   1 
ATOM   134   C CB  . ILE A 1 46  ? 116.594 96.537  73.154  1.00 7.78  ? 25   ILE A CB  1 
ATOM   135   C CG1 . ILE A 1 46  ? 115.412 95.571  73.169  1.00 7.78  ? 25   ILE A CG1 1 
ATOM   136   C CG2 . ILE A 1 46  ? 117.714 96.009  74.023  1.00 7.78  ? 25   ILE A CG2 1 
ATOM   137   C CD1 . ILE A 1 46  ? 115.787 94.156  72.838  1.00 7.78  ? 25   ILE A CD1 1 
ATOM   138   N N   . GLY A 1 47  ? 117.638 99.343  74.931  1.00 6.11  ? 26   GLY A N   1 
ATOM   139   C CA  . GLY A 1 47  ? 118.815 100.156 75.157  1.00 6.11  ? 26   GLY A CA  1 
ATOM   140   C C   . GLY A 1 47  ? 118.822 101.462 74.394  1.00 6.11  ? 26   GLY A C   1 
ATOM   141   O O   . GLY A 1 47  ? 119.807 101.788 73.725  1.00 6.11  ? 26   GLY A O   1 
ATOM   142   N N   . GLY A 1 48  ? 117.725 102.211 74.475  1.00 7.30  ? 27   GLY A N   1 
ATOM   143   C CA  . GLY A 1 48  ? 117.627 103.469 73.759  1.00 7.30  ? 27   GLY A CA  1 
ATOM   144   C C   . GLY A 1 48  ? 117.750 103.326 72.262  1.00 7.30  ? 27   GLY A C   1 
ATOM   145   O O   . GLY A 1 48  ? 118.231 104.246 71.595  1.00 7.30  ? 27   GLY A O   1 
ATOM   146   N N   . GLU A 1 49  ? 117.322 102.193 71.713  1.00 9.15  ? 28   GLU A N   1 
ATOM   147   C CA  . GLU A 1 49  ? 117.464 101.902 70.296  1.00 9.15  ? 28   GLU A CA  1 
ATOM   148   C C   . GLU A 1 49  ? 116.199 101.216 69.806  1.00 9.15  ? 28   GLU A C   1 
ATOM   149   O O   . GLU A 1 49  ? 115.289 100.916 70.581  1.00 9.15  ? 28   GLU A O   1 
ATOM   150   C CB  . GLU A 1 49  ? 118.693 101.026 70.031  1.00 9.15  ? 28   GLU A CB  1 
ATOM   151   C CG  . GLU A 1 49  ? 120.035 101.733 70.180  1.00 9.15  ? 28   GLU A CG  1 
ATOM   152   C CD  . GLU A 1 49  ? 120.108 103.056 69.438  1.00 9.15  ? 28   GLU A CD  1 
ATOM   153   O OE1 . GLU A 1 49  ? 120.766 103.984 69.950  1.00 9.15  ? 28   GLU A OE1 1 
ATOM   154   O OE2 . GLU A 1 49  ? 119.523 103.168 68.340  1.00 9.15  ? 28   GLU A OE2 1 
ATOM   155   N N   . TRP A 1 50  ? 116.142 100.974 68.501  1.00 11.15 ? 29   TRP A N   1 
ATOM   156   C CA  . TRP A 1 50  ? 115.074 100.201 67.873  1.00 11.15 ? 29   TRP A CA  1 
ATOM   157   C C   . TRP A 1 50  ? 115.737 99.029  67.164  1.00 11.15 ? 29   TRP A C   1 
ATOM   158   O O   . TRP A 1 50  ? 116.218 99.169  66.036  1.00 11.15 ? 29   TRP A O   1 
ATOM   159   C CB  . TRP A 1 50  ? 114.264 101.053 66.903  1.00 11.15 ? 29   TRP A CB  1 
ATOM   160   C CG  . TRP A 1 50  ? 113.437 102.074 67.580  1.00 11.15 ? 29   TRP A CG  1 
ATOM   161   C CD1 . TRP A 1 50  ? 113.699 103.403 67.683  1.00 11.15 ? 29   TRP A CD1 1 
ATOM   162   C CD2 . TRP A 1 50  ? 112.203 101.852 68.262  1.00 11.15 ? 29   TRP A CD2 1 
ATOM   163   N NE1 . TRP A 1 50  ? 112.705 104.027 68.391  1.00 11.15 ? 29   TRP A NE1 1 
ATOM   164   C CE2 . TRP A 1 50  ? 111.773 103.094 68.758  1.00 11.15 ? 29   TRP A CE2 1 
ATOM   165   C CE3 . TRP A 1 50  ? 111.421 100.723 68.503  1.00 11.15 ? 29   TRP A CE3 1 
ATOM   166   C CZ2 . TRP A 1 50  ? 110.595 103.238 69.477  1.00 11.15 ? 29   TRP A CZ2 1 
ATOM   167   C CZ3 . TRP A 1 50  ? 110.257 100.869 69.215  1.00 11.15 ? 29   TRP A CZ3 1 
ATOM   168   C CH2 . TRP A 1 50  ? 109.852 102.115 69.695  1.00 11.15 ? 29   TRP A CH2 1 
ATOM   169   N N   . VAL A 1 51  ? 115.768 97.878  67.824  1.00 14.68 ? 30   VAL A N   1 
ATOM   170   C CA  . VAL A 1 51  ? 116.456 96.700  67.316  1.00 14.68 ? 30   VAL A CA  1 
ATOM   171   C C   . VAL A 1 51  ? 115.431 95.626  66.985  1.00 14.68 ? 30   VAL A C   1 
ATOM   172   O O   . VAL A 1 51  ? 114.488 95.388  67.748  1.00 14.68 ? 30   VAL A O   1 
ATOM   173   C CB  . VAL A 1 51  ? 117.514 96.187  68.315  1.00 14.68 ? 30   VAL A CB  1 
ATOM   174   C CG1 . VAL A 1 51  ? 116.869 95.701  69.599  1.00 14.68 ? 30   VAL A CG1 1 
ATOM   175   C CG2 . VAL A 1 51  ? 118.345 95.081  67.682  1.00 14.68 ? 30   VAL A CG2 1 
ATOM   176   N N   . ALA A 1 52  ? 115.603 95.001  65.825  1.00 17.51 ? 31   ALA A N   1 
ATOM   177   C CA  . ALA A 1 52  ? 114.756 93.896  65.434  1.00 17.51 ? 31   ALA A CA  1 
ATOM   178   C C   . ALA A 1 52  ? 114.999 92.699  66.349  1.00 17.51 ? 31   ALA A C   1 
ATOM   179   O O   . ALA A 1 52  ? 116.055 92.590  66.976  1.00 17.51 ? 31   ALA A O   1 
ATOM   180   C CB  . ALA A 1 52  ? 115.026 93.511  63.983  1.00 17.51 ? 31   ALA A CB  1 
ATOM   181   N N   . PRO A 1 53  ? 114.026 91.796  66.455  1.00 21.35 ? 32   PRO A N   1 
ATOM   182   C CA  . PRO A 1 53  ? 114.238 90.566  67.227  1.00 21.35 ? 32   PRO A CA  1 
ATOM   183   C C   . PRO A 1 53  ? 115.374 89.740  66.649  1.00 21.35 ? 32   PRO A C   1 
ATOM   184   O O   . PRO A 1 53  ? 115.936 90.039  65.593  1.00 21.35 ? 32   PRO A O   1 
ATOM   185   C CB  . PRO A 1 53  ? 112.910 89.814  67.111  1.00 21.35 ? 32   PRO A CB  1 
ATOM   186   C CG  . PRO A 1 53  ? 111.949 90.742  66.524  1.00 21.35 ? 32   PRO A CG  1 
ATOM   187   C CD  . PRO A 1 53  ? 112.618 91.996  66.080  1.00 21.35 ? 32   PRO A CD  1 
ATOM   188   N N   . VAL A 1 54  ? 115.711 88.668  67.368  1.00 25.02 ? 33   VAL A N   1 
ATOM   189   C CA  . VAL A 1 54  ? 116.728 87.743  66.880  1.00 25.02 ? 33   VAL A CA  1 
ATOM   190   C C   . VAL A 1 54  ? 116.296 87.132  65.552  1.00 25.02 ? 33   VAL A C   1 
ATOM   191   O O   . VAL A 1 54  ? 117.108 86.965  64.634  1.00 25.02 ? 33   VAL A O   1 
ATOM   192   C CB  . VAL A 1 54  ? 117.028 86.670  67.944  1.00 25.02 ? 33   VAL A CB  1 
ATOM   193   C CG1 . VAL A 1 54  ? 115.764 85.908  68.324  1.00 25.02 ? 33   VAL A CG1 1 
ATOM   194   C CG2 . VAL A 1 54  ? 118.105 85.717  67.453  1.00 25.02 ? 33   VAL A CG2 1 
ATOM   195   N N   . SER A 1 55  ? 115.012 86.811  65.419  1.00 24.25 ? 34   SER A N   1 
ATOM   196   C CA  . SER A 1 55  ? 114.451 86.305  64.179  1.00 24.25 ? 34   SER A CA  1 
ATOM   197   C C   . SER A 1 55  ? 113.429 87.295  63.640  1.00 24.25 ? 34   SER A C   1 
ATOM   198   O O   . SER A 1 55  ? 112.880 88.120  64.375  1.00 24.25 ? 34   SER A O   1 
ATOM   199   C CB  . SER A 1 55  ? 113.799 84.932  64.374  1.00 24.25 ? 34   SER A CB  1 
ATOM   200   O OG  . SER A 1 55  ? 114.775 83.943  64.646  1.00 24.25 ? 34   SER A OG  1 
ATOM   201   N N   . GLY A 1 56  ? 113.174 87.200  62.338  1.00 25.06 ? 35   GLY A N   1 
ATOM   202   C CA  . GLY A 1 56  ? 112.245 88.091  61.674  1.00 25.06 ? 35   GLY A CA  1 
ATOM   203   C C   . GLY A 1 56  ? 110.793 87.832  62.016  1.00 25.06 ? 35   GLY A C   1 
ATOM   204   O O   . GLY A 1 56  ? 109.895 88.259  61.286  1.00 25.06 ? 35   GLY A O   1 
ATOM   205   N N   . ARG A 1 57  ? 110.547 87.116  63.111  1.00 24.77 ? 36   ARG A N   1 
ATOM   206   C CA  . ARG A 1 57  ? 109.188 86.845  63.561  1.00 24.77 ? 36   ARG A CA  1 
ATOM   207   C C   . ARG A 1 57  ? 108.471 88.137  63.930  1.00 24.77 ? 36   ARG A C   1 
ATOM   208   O O   . ARG A 1 57  ? 108.887 88.849  64.849  1.00 24.77 ? 36   ARG A O   1 
ATOM   209   C CB  . ARG A 1 57  ? 109.206 85.878  64.745  1.00 24.77 ? 36   ARG A CB  1 
ATOM   210   C CG  . ARG A 1 57  ? 109.882 84.547  64.445  1.00 24.77 ? 36   ARG A CG  1 
ATOM   211   C CD  . ARG A 1 57  ? 108.924 83.579  63.774  1.00 24.77 ? 36   ARG A CD  1 
ATOM   212   N NE  . ARG A 1 57  ? 108.740 83.875  62.359  1.00 24.77 ? 36   ARG A NE  1 
ATOM   213   C CZ  . ARG A 1 57  ? 107.605 83.673  61.699  1.00 24.77 ? 36   ARG A CZ  1 
ATOM   214   N NH1 . ARG A 1 57  ? 106.550 83.178  62.329  1.00 24.77 ? 36   ARG A NH1 1 
ATOM   215   N NH2 . ARG A 1 57  ? 107.526 83.970  60.409  1.00 24.77 ? 36   ARG A NH2 1 
ATOM   216   N N   . TYR A 1 58  ? 107.392 88.443  63.213  1.00 22.16 ? 37   TYR A N   1 
ATOM   217   C CA  . TYR A 1 58  ? 106.655 89.696  63.356  1.00 22.16 ? 37   TYR A CA  1 
ATOM   218   C C   . TYR A 1 58  ? 105.171 89.360  63.376  1.00 22.16 ? 37   TYR A C   1 
ATOM   219   O O   . TYR A 1 58  ? 104.607 89.002  62.338  1.00 22.16 ? 37   TYR A O   1 
ATOM   220   C CB  . TYR A 1 58  ? 106.968 90.642  62.194  1.00 22.16 ? 37   TYR A CB  1 
ATOM   221   C CG  . TYR A 1 58  ? 108.308 91.338  62.259  1.00 22.16 ? 37   TYR A CG  1 
ATOM   222   C CD1 . TYR A 1 58  ? 108.617 92.208  63.290  1.00 22.16 ? 37   TYR A CD1 1 
ATOM   223   C CD2 . TYR A 1 58  ? 109.247 91.159  61.253  1.00 22.16 ? 37   TYR A CD2 1 
ATOM   224   C CE1 . TYR A 1 58  ? 109.836 92.851  63.343  1.00 22.16 ? 37   TYR A CE1 1 
ATOM   225   C CE2 . TYR A 1 58  ? 110.472 91.790  61.297  1.00 22.16 ? 37   TYR A CE2 1 
ATOM   226   C CZ  . TYR A 1 58  ? 110.761 92.641  62.340  1.00 22.16 ? 37   TYR A CZ  1 
ATOM   227   O OH  . TYR A 1 58  ? 111.981 93.277  62.379  1.00 22.16 ? 37   TYR A OH  1 
ATOM   228   N N   . PHE A 1 59  ? 104.528 89.464  64.535  1.00 16.55 ? 38   PHE A N   1 
ATOM   229   C CA  . PHE A 1 59  ? 103.093 89.228  64.566  1.00 16.55 ? 38   PHE A CA  1 
ATOM   230   C C   . PHE A 1 59  ? 102.377 90.528  64.204  1.00 16.55 ? 38   PHE A C   1 
ATOM   231   O O   . PHE A 1 59  ? 103.004 91.516  63.816  1.00 16.55 ? 38   PHE A O   1 
ATOM   232   C CB  . PHE A 1 59  ? 102.662 88.623  65.906  1.00 16.55 ? 38   PHE A CB  1 
ATOM   233   C CG  . PHE A 1 59  ? 102.680 89.572  67.067  1.00 16.55 ? 38   PHE A CG  1 
ATOM   234   C CD1 . PHE A 1 59  ? 101.579 90.353  67.361  1.00 16.55 ? 38   PHE A CD1 1 
ATOM   235   C CD2 . PHE A 1 59  ? 103.775 89.636  67.905  1.00 16.55 ? 38   PHE A CD2 1 
ATOM   236   C CE1 . PHE A 1 59  ? 101.586 91.204  68.440  1.00 16.55 ? 38   PHE A CE1 1 
ATOM   237   C CE2 . PHE A 1 59  ? 103.785 90.485  68.987  1.00 16.55 ? 38   PHE A CE2 1 
ATOM   238   C CZ  . PHE A 1 59  ? 102.690 91.268  69.254  1.00 16.55 ? 38   PHE A CZ  1 
ATOM   239   N N   . THR A 1 60  ? 101.051 90.538  64.300  1.00 15.93 ? 39   THR A N   1 
ATOM   240   C CA  . THR A 1 60  ? 100.242 91.614  63.741  1.00 15.93 ? 39   THR A CA  1 
ATOM   241   C C   . THR A 1 60  ? 99.305  92.169  64.801  1.00 15.93 ? 39   THR A C   1 
ATOM   242   O O   . THR A 1 60  ? 98.501  91.427  65.372  1.00 15.93 ? 39   THR A O   1 
ATOM   243   C CB  . THR A 1 60  ? 99.441  91.119  62.535  1.00 15.93 ? 39   THR A CB  1 
ATOM   244   O OG1 . THR A 1 60  ? 100.322 90.905  61.426  1.00 15.93 ? 39   THR A OG1 1 
ATOM   245   C CG2 . THR A 1 60  ? 98.395  92.131  62.149  1.00 15.93 ? 39   THR A CG2 1 
ATOM   246   N N   . ASN A 1 61  ? 99.409  93.468  65.056  1.00 14.10 ? 40   ASN A N   1 
ATOM   247   C CA  . ASN A 1 61  ? 98.438  94.154  65.892  1.00 14.10 ? 40   ASN A CA  1 
ATOM   248   C C   . ASN A 1 61  ? 97.154  94.398  65.105  1.00 14.10 ? 40   ASN A C   1 
ATOM   249   O O   . ASN A 1 61  ? 97.164  94.509  63.879  1.00 14.10 ? 40   ASN A O   1 
ATOM   250   C CB  . ASN A 1 61  ? 99.019  95.473  66.397  1.00 14.10 ? 40   ASN A CB  1 
ATOM   251   C CG  . ASN A 1 61  ? 98.211  96.076  67.522  1.00 14.10 ? 40   ASN A CG  1 
ATOM   252   O OD1 . ASN A 1 61  ? 97.460  95.384  68.205  1.00 14.10 ? 40   ASN A OD1 1 
ATOM   253   N ND2 . ASN A 1 61  ? 98.360  97.376  67.718  1.00 14.10 ? 40   ASN A ND2 1 
ATOM   254   N N   . THR A 1 62  ? 96.037  94.480  65.822  1.00 15.00 ? 41   THR A N   1 
ATOM   255   C CA  . THR A 1 62  ? 94.738  94.622  65.175  1.00 15.00 ? 41   THR A CA  1 
ATOM   256   C C   . THR A 1 62  ? 93.843  95.507  66.025  1.00 15.00 ? 41   THR A C   1 
ATOM   257   O O   . THR A 1 62  ? 93.663  95.246  67.217  1.00 15.00 ? 41   THR A O   1 
ATOM   258   C CB  . THR A 1 62  ? 94.082  93.254  64.959  1.00 15.00 ? 41   THR A CB  1 
ATOM   259   O OG1 . THR A 1 62  ? 94.759  92.562  63.904  1.00 15.00 ? 41   THR A OG1 1 
ATOM   260   C CG2 . THR A 1 62  ? 92.619  93.410  64.596  1.00 15.00 ? 41   THR A CG2 1 
ATOM   261   N N   . THR A 1 63  ? 93.281  96.538  65.411  1.00 12.97 ? 42   THR A N   1 
ATOM   262   C CA  . THR A 1 63  ? 92.450  97.479  66.149  1.00 12.97 ? 42   THR A CA  1 
ATOM   263   C C   . THR A 1 63  ? 91.112  96.845  66.518  1.00 12.97 ? 42   THR A C   1 
ATOM   264   O O   . THR A 1 63  ? 90.444  96.265  65.658  1.00 12.97 ? 42   THR A O   1 
ATOM   265   C CB  . THR A 1 63  ? 92.233  98.755  65.339  1.00 12.97 ? 42   THR A CB  1 
ATOM   266   O OG1 . THR A 1 63  ? 91.303  99.604  66.021  1.00 12.97 ? 42   THR A OG1 1 
ATOM   267   C CG2 . THR A 1 63  ? 91.726  98.443  63.947  1.00 12.97 ? 42   THR A CG2 1 
ATOM   268   N N   . PRO A 1 64  ? 90.707  96.901  67.785  1.00 12.66 ? 43   PRO A N   1 
ATOM   269   C CA  . PRO A 1 64  ? 89.370  96.411  68.143  1.00 12.66 ? 43   PRO A CA  1 
ATOM   270   C C   . PRO A 1 64  ? 88.241  97.199  67.506  1.00 12.66 ? 43   PRO A C   1 
ATOM   271   O O   . PRO A 1 64  ? 87.168  96.633  67.276  1.00 12.66 ? 43   PRO A O   1 
ATOM   272   C CB  . PRO A 1 64  ? 89.350  96.540  69.673  1.00 12.66 ? 43   PRO A CB  1 
ATOM   273   C CG  . PRO A 1 64  ? 90.769  96.646  70.074  1.00 12.66 ? 43   PRO A CG  1 
ATOM   274   C CD  . PRO A 1 64  ? 91.456  97.356  68.962  1.00 12.66 ? 43   PRO A CD  1 
ATOM   275   N N   . ILE A 1 65  ? 88.448  98.490  67.226  1.00 12.94 ? 44   ILE A N   1 
ATOM   276   C CA  . ILE A 1 65  ? 87.355  99.352  66.776  1.00 12.94 ? 44   ILE A CA  1 
ATOM   277   C C   . ILE A 1 65  ? 86.722  98.790  65.515  1.00 12.94 ? 44   ILE A C   1 
ATOM   278   O O   . ILE A 1 65  ? 85.499  98.636  65.421  1.00 12.94 ? 44   ILE A O   1 
ATOM   279   C CB  . ILE A 1 65  ? 87.865  100.784 66.542  1.00 12.94 ? 44   ILE A CB  1 
ATOM   280   C CG1 . ILE A 1 65  ? 88.183  101.473 67.865  1.00 12.94 ? 44   ILE A CG1 1 
ATOM   281   C CG2 . ILE A 1 65  ? 86.852  101.581 65.746  1.00 12.94 ? 44   ILE A CG2 1 
ATOM   282   C CD1 . ILE A 1 65  ? 89.289  102.481 67.759  1.00 12.94 ? 44   ILE A CD1 1 
ATOM   283   N N   . THR A 1 66  ? 87.550  98.485  64.524  1.00 15.27 ? 45   THR A N   1 
ATOM   284   C CA  . THR A 1 66  ? 87.139  97.839  63.284  1.00 15.27 ? 45   THR A CA  1 
ATOM   285   C C   . THR A 1 66  ? 88.202  96.779  63.047  1.00 15.27 ? 45   THR A C   1 
ATOM   286   O O   . THR A 1 66  ? 89.278  97.107  62.541  1.00 15.27 ? 45   THR A O   1 
ATOM   287   C CB  . THR A 1 66  ? 87.087  98.821  62.119  1.00 15.27 ? 45   THR A CB  1 
ATOM   288   O OG1 . THR A 1 66  ? 88.407  99.307  61.852  1.00 15.27 ? 45   THR A OG1 1 
ATOM   289   C CG2 . THR A 1 66  ? 86.205  99.999  62.446  1.00 15.27 ? 45   THR A CG2 1 
ATOM   290   N N   . GLY A 1 67  ? 87.919  95.532  63.422  1.00 16.43 ? 46   GLY A N   1 
ATOM   291   C CA  . GLY A 1 67  ? 88.947  94.508  63.400  1.00 16.43 ? 46   GLY A CA  1 
ATOM   292   C C   . GLY A 1 67  ? 89.692  94.478  62.084  1.00 16.43 ? 46   GLY A C   1 
ATOM   293   O O   . GLY A 1 67  ? 89.156  94.059  61.055  1.00 16.43 ? 46   GLY A O   1 
ATOM   294   N N   . ALA A 1 68  ? 90.943  94.927  62.122  1.00 18.33 ? 47   ALA A N   1 
ATOM   295   C CA  . ALA A 1 68  ? 91.742  95.168  60.930  1.00 18.33 ? 47   ALA A CA  1 
ATOM   296   C C   . ALA A 1 68  ? 93.160  95.498  61.366  1.00 18.33 ? 47   ALA A C   1 
ATOM   297   O O   . ALA A 1 68  ? 93.399  95.906  62.506  1.00 18.33 ? 47   ALA A O   1 
ATOM   298   C CB  . ALA A 1 68  ? 91.168  96.304  60.080  1.00 18.33 ? 47   ALA A CB  1 
ATOM   299   N N   . GLU A 1 69  ? 94.092  95.332  60.437  1.00 20.26 ? 48   GLU A N   1 
ATOM   300   C CA  . GLU A 1 69  ? 95.503  95.501  60.747  1.00 20.26 ? 48   GLU A CA  1 
ATOM   301   C C   . GLU A 1 69  ? 95.844  96.972  60.947  1.00 20.26 ? 48   GLU A C   1 
ATOM   302   O O   . GLU A 1 69  ? 95.387  97.841  60.201  1.00 20.26 ? 48   GLU A O   1 
ATOM   303   C CB  . GLU A 1 69  ? 96.354  94.909  59.626  1.00 20.26 ? 48   GLU A CB  1 
ATOM   304   C CG  . GLU A 1 69  ? 96.356  93.388  59.586  1.00 20.26 ? 48   GLU A CG  1 
ATOM   305   C CD  . GLU A 1 69  ? 95.029  92.794  59.146  1.00 20.26 ? 48   GLU A CD  1 
ATOM   306   O OE1 . GLU A 1 69  ? 94.151  93.554  58.687  1.00 20.26 ? 48   GLU A OE1 1 
ATOM   307   O OE2 . GLU A 1 69  ? 94.860  91.562  59.268  1.00 20.26 ? 48   GLU A OE2 1 
ATOM   308   N N   . ILE A 1 70  ? 96.648  97.249  61.972  1.00 18.14 ? 49   ILE A N   1 
ATOM   309   C CA  . ILE A 1 70  ? 97.123  98.602  62.237  1.00 18.14 ? 49   ILE A CA  1 
ATOM   310   C C   . ILE A 1 70  ? 98.633  98.595  62.410  1.00 18.14 ? 49   ILE A C   1 
ATOM   311   O O   . ILE A 1 70  ? 99.194  99.468  63.081  1.00 18.14 ? 49   ILE A O   1 
ATOM   312   C CB  . ILE A 1 70  ? 96.437  99.212  63.470  1.00 18.14 ? 49   ILE A CB  1 
ATOM   313   C CG1 . ILE A 1 70  ? 96.511  98.251  64.653  1.00 18.14 ? 49   ILE A CG1 1 
ATOM   314   C CG2 . ILE A 1 70  ? 95.008  99.575  63.145  1.00 18.14 ? 49   ILE A CG2 1 
ATOM   315   C CD1 . ILE A 1 70  ? 96.000  98.842  65.945  1.00 18.14 ? 49   ILE A CD1 1 
ATOM   316   N N   . GLY A 1 71  ? 99.301  97.611  61.823  1.00 17.80 ? 50   GLY A N   1 
ATOM   317   C CA  . GLY A 1 71  ? 100.745 97.519  61.885  1.00 17.80 ? 50   GLY A CA  1 
ATOM   318   C C   . GLY A 1 71  ? 101.208 96.140  62.306  1.00 17.80 ? 50   GLY A C   1 
ATOM   319   O O   . GLY A 1 71  ? 100.431 95.283  62.718  1.00 17.80 ? 50   GLY A O   1 
ATOM   320   N N   . GLN A 1 72  ? 102.519 95.950  62.197  1.00 20.55 ? 51   GLN A N   1 
ATOM   321   C CA  . GLN A 1 72  ? 103.152 94.648  62.361  1.00 20.55 ? 51   GLN A CA  1 
ATOM   322   C C   . GLN A 1 72  ? 104.168 94.742  63.489  1.00 20.55 ? 51   GLN A C   1 
ATOM   323   O O   . GLN A 1 72  ? 105.091 95.559  63.430  1.00 20.55 ? 51   GLN A O   1 
ATOM   324   C CB  . GLN A 1 72  ? 103.811 94.220  61.051  1.00 20.55 ? 51   GLN A CB  1 
ATOM   325   C CG  . GLN A 1 72  ? 104.358 92.816  61.020  1.00 20.55 ? 51   GLN A CG  1 
ATOM   326   C CD  . GLN A 1 72  ? 104.899 92.461  59.651  1.00 20.55 ? 51   GLN A CD  1 
ATOM   327   O OE1 . GLN A 1 72  ? 104.919 93.297  58.751  1.00 20.55 ? 51   GLN A OE1 1 
ATOM   328   N NE2 . GLN A 1 72  ? 105.320 91.215  59.479  1.00 20.55 ? 51   GLN A NE2 1 
ATOM   329   N N   . ILE A 1 73  ? 104.006 93.897  64.504  1.00 16.59 ? 52   ILE A N   1 
ATOM   330   C CA  . ILE A 1 73  ? 104.736 94.008  65.761  1.00 16.59 ? 52   ILE A CA  1 
ATOM   331   C C   . ILE A 1 73  ? 105.691 92.832  65.898  1.00 16.59 ? 52   ILE A C   1 
ATOM   332   O O   . ILE A 1 73  ? 105.354 91.697  65.546  1.00 16.59 ? 52   ILE A O   1 
ATOM   333   C CB  . ILE A 1 73  ? 103.769 94.078  66.957  1.00 16.59 ? 52   ILE A CB  1 
ATOM   334   C CG1 . ILE A 1 73  ? 102.848 95.284  66.818  1.00 16.59 ? 52   ILE A CG1 1 
ATOM   335   C CG2 . ILE A 1 73  ? 104.531 94.169  68.253  1.00 16.59 ? 52   ILE A CG2 1 
ATOM   336   C CD1 . ILE A 1 73  ? 103.560 96.543  66.394  1.00 16.59 ? 52   ILE A CD1 1 
ATOM   337   N N   . ALA A 1 74  ? 106.883 93.113  66.413  1.00 17.65 ? 53   ALA A N   1 
ATOM   338   C CA  . ALA A 1 74  ? 107.928 92.109  66.538  1.00 17.65 ? 53   ALA A CA  1 
ATOM   339   C C   . ALA A 1 74  ? 107.554 91.017  67.534  1.00 17.65 ? 53   ALA A C   1 
ATOM   340   O O   . ALA A 1 74  ? 107.007 91.290  68.605  1.00 17.65 ? 53   ALA A O   1 
ATOM   341   C CB  . ALA A 1 74  ? 109.228 92.779  66.966  1.00 17.65 ? 53   ALA A CB  1 
ATOM   342   N N   . ARG A 1 75  ? 107.868 89.773  67.176  1.00 20.12 ? 54   ARG A N   1 
ATOM   343   C CA  . ARG A 1 75  ? 107.641 88.612  68.029  1.00 20.12 ? 54   ARG A CA  1 
ATOM   344   C C   . ARG A 1 75  ? 108.949 88.259  68.728  1.00 20.12 ? 54   ARG A C   1 
ATOM   345   O O   . ARG A 1 75  ? 109.945 87.953  68.065  1.00 20.12 ? 54   ARG A O   1 
ATOM   346   C CB  . ARG A 1 75  ? 107.134 87.429  67.208  1.00 20.12 ? 54   ARG A CB  1 
ATOM   347   C CG  . ARG A 1 75  ? 105.958 86.697  67.818  1.00 20.12 ? 54   ARG A CG  1 
ATOM   348   C CD  . ARG A 1 75  ? 105.540 85.514  66.961  1.00 20.12 ? 54   ARG A CD  1 
ATOM   349   N NE  . ARG A 1 75  ? 106.546 84.458  66.953  1.00 20.12 ? 54   ARG A NE  1 
ATOM   350   C CZ  . ARG A 1 75  ? 106.414 83.308  66.300  1.00 20.12 ? 54   ARG A CZ  1 
ATOM   351   N NH1 . ARG A 1 75  ? 105.315 83.064  65.602  1.00 20.12 ? 54   ARG A NH1 1 
ATOM   352   N NH2 . ARG A 1 75  ? 107.378 82.399  66.351  1.00 20.12 ? 54   ARG A NH2 1 
ATOM   353   N N   . SER A 1 76  ? 108.943 88.286  70.058  1.00 17.86 ? 55   SER A N   1 
ATOM   354   C CA  . SER A 1 76  ? 110.170 88.239  70.842  1.00 17.86 ? 55   SER A CA  1 
ATOM   355   C C   . SER A 1 76  ? 110.360 86.869  71.479  1.00 17.86 ? 55   SER A C   1 
ATOM   356   O O   . SER A 1 76  ? 109.516 86.418  72.259  1.00 17.86 ? 55   SER A O   1 
ATOM   357   C CB  . SER A 1 76  ? 110.159 89.317  71.918  1.00 17.86 ? 55   SER A CB  1 
ATOM   358   O OG  . SER A 1 76  ? 110.109 90.604  71.338  1.00 17.86 ? 55   SER A OG  1 
ATOM   359   N N   . GLU A 1 77  ? 111.480 86.228  71.163  1.00 20.40 ? 56   GLU A N   1 
ATOM   360   C CA  . GLU A 1 77  ? 111.884 84.989  71.804  1.00 20.40 ? 56   GLU A CA  1 
ATOM   361   C C   . GLU A 1 77  ? 112.698 85.321  73.054  1.00 20.40 ? 56   GLU A C   1 
ATOM   362   O O   . GLU A 1 77  ? 112.734 86.465  73.510  1.00 20.40 ? 56   GLU A O   1 
ATOM   363   C CB  . GLU A 1 77  ? 112.666 84.119  70.825  1.00 20.40 ? 56   GLU A CB  1 
ATOM   364   C CG  . GLU A 1 77  ? 112.019 83.995  69.460  1.00 20.40 ? 56   GLU A CG  1 
ATOM   365   C CD  . GLU A 1 77  ? 110.813 83.080  69.460  1.00 20.40 ? 56   GLU A CD  1 
ATOM   366   O OE1 . GLU A 1 77  ? 109.677 83.596  69.499  1.00 20.40 ? 56   GLU A OE1 1 
ATOM   367   O OE2 . GLU A 1 77  ? 111.001 81.845  69.413  1.00 20.40 ? 56   GLU A OE2 1 
ATOM   368   N N   . ALA A 1 78  ? 113.362 84.318  73.627  1.00 17.01 ? 57   ALA A N   1 
ATOM   369   C CA  . ALA A 1 78  ? 114.150 84.556  74.832  1.00 17.01 ? 57   ALA A CA  1 
ATOM   370   C C   . ALA A 1 78  ? 115.390 85.394  74.545  1.00 17.01 ? 57   ALA A C   1 
ATOM   371   O O   . ALA A 1 78  ? 115.880 86.089  75.441  1.00 17.01 ? 57   ALA A O   1 
ATOM   372   C CB  . ALA A 1 78  ? 114.544 83.227  75.473  1.00 17.01 ? 57   ALA A CB  1 
ATOM   373   N N   . GLY A 1 79  ? 115.906 85.344  73.313  1.00 16.42 ? 58   GLY A N   1 
ATOM   374   C CA  . GLY A 1 79  ? 117.123 86.078  72.997  1.00 16.42 ? 58   GLY A CA  1 
ATOM   375   C C   . GLY A 1 79  ? 116.955 87.582  73.103  1.00 16.42 ? 58   GLY A C   1 
ATOM   376   O O   . GLY A 1 79  ? 117.871 88.293  73.531  1.00 16.42 ? 58   GLY A O   1 
ATOM   377   N N   . ASP A 1 80  ? 115.784 88.089  72.714  1.00 17.02 ? 59   ASP A N   1 
ATOM   378   C CA  . ASP A 1 80  ? 115.522 89.516  72.860  1.00 17.02 ? 59   ASP A CA  1 
ATOM   379   C C   . ASP A 1 80  ? 115.452 89.907  74.327  1.00 17.02 ? 59   ASP A C   1 
ATOM   380   O O   . ASP A 1 80  ? 115.891 90.997  74.706  1.00 17.02 ? 59   ASP A O   1 
ATOM   381   C CB  . ASP A 1 80  ? 114.232 89.891  72.141  1.00 17.02 ? 59   ASP A CB  1 
ATOM   382   C CG  . ASP A 1 80  ? 114.208 89.415  70.706  1.00 17.02 ? 59   ASP A CG  1 
ATOM   383   O OD1 . ASP A 1 80  ? 115.288 89.115  70.154  1.00 17.02 ? 59   ASP A OD1 1 
ATOM   384   O OD2 . ASP A 1 80  ? 113.106 89.338  70.132  1.00 17.02 ? 59   ASP A OD2 1 
ATOM   385   N N   . ILE A 1 81  ? 114.910 89.027  75.169  1.00 12.81 ? 60   ILE A N   1 
ATOM   386   C CA  . ILE A 1 81  ? 114.962 89.261  76.604  1.00 12.81 ? 60   ILE A CA  1 
ATOM   387   C C   . ILE A 1 81  ? 116.405 89.313  77.083  1.00 12.81 ? 60   ILE A C   1 
ATOM   388   O O   . ILE A 1 81  ? 116.737 90.071  78.000  1.00 12.81 ? 60   ILE A O   1 
ATOM   389   C CB  . ILE A 1 81  ? 114.150 88.184  77.346  1.00 12.81 ? 60   ILE A CB  1 
ATOM   390   C CG1 . ILE A 1 81  ? 112.659 88.361  77.061  1.00 12.81 ? 60   ILE A CG1 1 
ATOM   391   C CG2 . ILE A 1 81  ? 114.412 88.240  78.840  1.00 12.81 ? 60   ILE A CG2 1 
ATOM   392   C CD1 . ILE A 1 81  ? 112.023 89.478  77.839  1.00 12.81 ? 60   ILE A CD1 1 
ATOM   393   N N   . GLU A 1 82  ? 117.296 88.551  76.450  1.00 13.45 ? 61   GLU A N   1 
ATOM   394   C CA  . GLU A 1 82  ? 118.696 88.586  76.855  1.00 13.45 ? 61   GLU A CA  1 
ATOM   395   C C   . GLU A 1 82  ? 119.363 89.894  76.449  1.00 13.45 ? 61   GLU A C   1 
ATOM   396   O O   . GLU A 1 82  ? 120.128 90.473  77.229  1.00 13.45 ? 61   GLU A O   1 
ATOM   397   C CB  . GLU A 1 82  ? 119.440 87.389  76.273  1.00 13.45 ? 61   GLU A CB  1 
ATOM   398   C CG  . GLU A 1 82  ? 118.837 86.053  76.665  1.00 13.45 ? 61   GLU A CG  1 
ATOM   399   C CD  . GLU A 1 82  ? 118.444 85.985  78.132  1.00 13.45 ? 61   GLU A CD  1 
ATOM   400   O OE1 . GLU A 1 82  ? 119.248 86.401  78.993  1.00 13.45 ? 61   GLU A OE1 1 
ATOM   401   O OE2 . GLU A 1 82  ? 117.327 85.508  78.425  1.00 13.45 ? 61   GLU A OE2 1 
ATOM   402   N N   . LEU A 1 83  ? 119.080 90.386  75.240  1.00 10.60 ? 62   LEU A N   1 
ATOM   403   C CA  . LEU A 1 83  ? 119.594 91.698  74.854  1.00 10.60 ? 62   LEU A CA  1 
ATOM   404   C C   . LEU A 1 83  ? 119.060 92.789  75.774  1.00 10.60 ? 62   LEU A C   1 
ATOM   405   O O   . LEU A 1 83  ? 119.806 93.687  76.202  1.00 10.60 ? 62   LEU A O   1 
ATOM   406   C CB  . LEU A 1 83  ? 119.221 92.004  73.406  1.00 10.60 ? 62   LEU A CB  1 
ATOM   407   C CG  . LEU A 1 83  ? 119.733 91.044  72.341  1.00 10.60 ? 62   LEU A CG  1 
ATOM   408   C CD1 . LEU A 1 83  ? 119.655 91.696  70.976  1.00 10.60 ? 62   LEU A CD1 1 
ATOM   409   C CD2 . LEU A 1 83  ? 121.155 90.624  72.658  1.00 10.60 ? 62   LEU A CD2 1 
ATOM   410   N N   . ALA A 1 84  ? 117.765 92.725  76.088  1.00 7.71  ? 63   ALA A N   1 
ATOM   411   C CA  . ALA A 1 84  ? 117.160 93.713  76.967  1.00 7.71  ? 63   ALA A CA  1 
ATOM   412   C C   . ALA A 1 84  ? 117.794 93.679  78.344  1.00 7.71  ? 63   ALA A C   1 
ATOM   413   O O   . ALA A 1 84  ? 118.058 94.728  78.936  1.00 7.71  ? 63   ALA A O   1 
ATOM   414   C CB  . ALA A 1 84  ? 115.657 93.476  77.063  1.00 7.71  ? 63   ALA A CB  1 
ATOM   415   N N   . LEU A 1 85  ? 118.058 92.483  78.868  1.00 7.24  ? 64   LEU A N   1 
ATOM   416   C CA  . LEU A 1 85  ? 118.672 92.386  80.184  1.00 7.24  ? 64   LEU A CA  1 
ATOM   417   C C   . LEU A 1 85  ? 120.119 92.858  80.168  1.00 7.24  ? 64   LEU A C   1 
ATOM   418   O O   . LEU A 1 85  ? 120.575 93.457  81.144  1.00 7.24  ? 64   LEU A O   1 
ATOM   419   C CB  . LEU A 1 85  ? 118.569 90.957  80.704  1.00 7.24  ? 64   LEU A CB  1 
ATOM   420   C CG  . LEU A 1 85  ? 117.167 90.586  81.180  1.00 7.24  ? 64   LEU A CG  1 
ATOM   421   C CD1 . LEU A 1 85  ? 117.028 89.089  81.350  1.00 7.24  ? 64   LEU A CD1 1 
ATOM   422   C CD2 . LEU A 1 85  ? 116.847 91.307  82.470  1.00 7.24  ? 64   LEU A CD2 1 
ATOM   423   N N   . ASP A 1 86  ? 120.848 92.627  79.077  1.00 8.30  ? 65   ASP A N   1 
ATOM   424   C CA  . ASP A 1 86  ? 122.209 93.151  78.987  1.00 8.30  ? 65   ASP A CA  1 
ATOM   425   C C   . ASP A 1 86  ? 122.215 94.675  79.043  1.00 8.30  ? 65   ASP A C   1 
ATOM   426   O O   . ASP A 1 86  ? 122.962 95.284  79.829  1.00 8.30  ? 65   ASP A O   1 
ATOM   427   C CB  . ASP A 1 86  ? 122.876 92.657  77.706  1.00 8.30  ? 65   ASP A CB  1 
ATOM   428   C CG  . ASP A 1 86  ? 123.288 91.205  77.790  1.00 8.30  ? 65   ASP A CG  1 
ATOM   429   O OD1 . ASP A 1 86  ? 123.737 90.775  78.872  1.00 8.30  ? 65   ASP A OD1 1 
ATOM   430   O OD2 . ASP A 1 86  ? 123.163 90.490  76.777  1.00 8.30  ? 65   ASP A OD2 1 
ATOM   431   N N   . ALA A 1 87  ? 121.379 95.311  78.216  1.00 6.15  ? 66   ALA A N   1 
ATOM   432   C CA  . ALA A 1 87  ? 121.310 96.770  78.238  1.00 6.15  ? 66   ALA A CA  1 
ATOM   433   C C   . ALA A 1 87  ? 120.848 97.281  79.598  1.00 6.15  ? 66   ALA A C   1 
ATOM   434   O O   . ALA A 1 87  ? 121.386 98.270  80.121  1.00 6.15  ? 66   ALA A O   1 
ATOM   435   C CB  . ALA A 1 87  ? 120.384 97.268  77.133  1.00 6.15  ? 66   ALA A CB  1 
ATOM   436   N N   . ALA A 1 88  ? 119.857 96.613  80.190  1.00 4.97  ? 67   ALA A N   1 
ATOM   437   C CA  . ALA A 1 88  ? 119.379 97.003  81.506  1.00 4.97  ? 67   ALA A CA  1 
ATOM   438   C C   . ALA A 1 88  ? 120.467 96.881  82.556  1.00 4.97  ? 67   ALA A C   1 
ATOM   439   O O   . ALA A 1 88  ? 120.522 97.693  83.475  1.00 4.97  ? 67   ALA A O   1 
ATOM   440   C CB  . ALA A 1 88  ? 118.167 96.163  81.897  1.00 4.97  ? 67   ALA A CB  1 
ATOM   441   N N   . HIS A 1 89  ? 121.358 95.899  82.435  1.00 6.66  ? 68   HIS A N   1 
ATOM   442   C CA  . HIS A 1 89  ? 122.411 95.757  83.436  1.00 6.66  ? 68   HIS A CA  1 
ATOM   443   C C   . HIS A 1 89  ? 123.492 96.823  83.282  1.00 6.66  ? 68   HIS A C   1 
ATOM   444   O O   . HIS A 1 89  ? 123.988 97.354  84.285  1.00 6.66  ? 68   HIS A O   1 
ATOM   445   C CB  . HIS A 1 89  ? 123.014 94.356  83.368  1.00 6.66  ? 68   HIS A CB  1 
ATOM   446   C CG  . HIS A 1 89  ? 122.195 93.326  84.076  1.00 6.66  ? 68   HIS A CG  1 
ATOM   447   N ND1 . HIS A 1 89  ? 121.985 93.352  85.436  1.00 6.66  ? 68   HIS A ND1 1 
ATOM   448   C CD2 . HIS A 1 89  ? 121.522 92.248  83.613  1.00 6.66  ? 68   HIS A CD2 1 
ATOM   449   C CE1 . HIS A 1 89  ? 121.221 92.333  85.781  1.00 6.66  ? 68   HIS A CE1 1 
ATOM   450   N NE2 . HIS A 1 89  ? 120.927 91.647  84.693  1.00 6.66  ? 68   HIS A NE2 1 
ATOM   451   N N   . ALA A 1 90  ? 123.863 97.159  82.045  1.00 5.88  ? 69   ALA A N   1 
ATOM   452   C CA  . ALA A 1 90  ? 124.805 98.263  81.855  1.00 5.88  ? 69   ALA A CA  1 
ATOM   453   C C   . ALA A 1 90  ? 124.251 99.563  82.442  1.00 5.88  ? 69   ALA A C   1 
ATOM   454   O O   . ALA A 1 90  ? 124.918 100.262 83.234  1.00 5.88  ? 69   ALA A O   1 
ATOM   455   C CB  . ALA A 1 90  ? 125.122 98.428  80.370  1.00 5.88  ? 69   ALA A CB  1 
ATOM   456   N N   . ALA A 1 91  ? 123.014 99.899  82.079  1.00 4.82  ? 70   ALA A N   1 
ATOM   457   C CA  . ALA A 1 91  ? 122.432 101.106 82.642  1.00 4.82  ? 70   ALA A CA  1 
ATOM   458   C C   . ALA A 1 91  ? 122.176 100.958 84.134  1.00 4.82  ? 70   ALA A C   1 
ATOM   459   O O   . ALA A 1 91  ? 122.082 101.959 84.840  1.00 4.82  ? 70   ALA A O   1 
ATOM   460   C CB  . ALA A 1 91  ? 121.154 101.469 81.900  1.00 4.82  ? 70   ALA A CB  1 
ATOM   461   N N   . LYS A 1 92  ? 122.037 99.731  84.634  1.00 5.84  ? 71   LYS A N   1 
ATOM   462   C CA  . LYS A 1 92  ? 121.936 99.530  86.072  1.00 5.84  ? 71   LYS A CA  1 
ATOM   463   C C   . LYS A 1 92  ? 123.207 99.990  86.755  1.00 5.84  ? 71   LYS A C   1 
ATOM   464   O O   . LYS A 1 92  ? 123.167 100.671 87.787  1.00 5.84  ? 71   LYS A O   1 
ATOM   465   C CB  . LYS A 1 92  ? 121.667 98.058  86.375  1.00 5.84  ? 71   LYS A CB  1 
ATOM   466   C CG  . LYS A 1 92  ? 121.988 97.656  87.801  1.00 5.84  ? 71   LYS A CG  1 
ATOM   467   C CD  . LYS A 1 92  ? 122.046 96.150  87.959  1.00 5.84  ? 71   LYS A CD  1 
ATOM   468   C CE  . LYS A 1 92  ? 123.429 95.618  87.668  1.00 5.84  ? 71   LYS A CE  1 
ATOM   469   N NZ  . LYS A 1 92  ? 123.530 94.177  88.005  1.00 5.84  ? 71   LYS A NZ  1 
ATOM   470   N N   . GLU A 1 93  ? 124.351 99.622  86.182  1.00 6.58  ? 72   GLU A N   1 
ATOM   471   C CA  . GLU A 1 93  ? 125.622 100.105 86.708  1.00 6.58  ? 72   GLU A CA  1 
ATOM   472   C C   . GLU A 1 93  ? 125.642 101.627 86.756  1.00 6.58  ? 72   GLU A C   1 
ATOM   473   O O   . GLU A 1 93  ? 125.919 102.222 87.802  1.00 6.58  ? 72   GLU A O   1 
ATOM   474   C CB  . GLU A 1 93  ? 126.786 99.583  85.863  1.00 6.58  ? 72   GLU A CB  1 
ATOM   475   C CG  . GLU A 1 93  ? 126.689 98.123  85.462  1.00 6.58  ? 72   GLU A CG  1 
ATOM   476   C CD  . GLU A 1 93  ? 126.859 97.182  86.635  1.00 6.58  ? 72   GLU A CD  1 
ATOM   477   O OE1 . GLU A 1 93  ? 126.384 96.030  86.549  1.00 6.58  ? 72   GLU A OE1 1 
ATOM   478   O OE2 . GLU A 1 93  ? 127.467 97.592  87.645  1.00 6.58  ? 72   GLU A OE2 1 
ATOM   479   N N   . LYS A 1 94  ? 125.321 102.279 85.635  1.00 5.15  ? 73   LYS A N   1 
ATOM   480   C CA  . LYS A 1 94  ? 125.504 103.736 85.605  1.00 5.15  ? 73   LYS A CA  1 
ATOM   481   C C   . LYS A 1 94  ? 124.343 104.504 86.241  1.00 5.15  ? 73   LYS A C   1 
ATOM   482   O O   . LYS A 1 94  ? 124.519 105.199 87.248  1.00 5.15  ? 73   LYS A O   1 
ATOM   483   C CB  . LYS A 1 94  ? 125.732 104.222 84.176  1.00 5.15  ? 73   LYS A CB  1 
ATOM   484   C CG  . LYS A 1 94  ? 126.462 105.550 84.136  1.00 5.15  ? 73   LYS A CG  1 
ATOM   485   C CD  . LYS A 1 94  ? 127.705 105.510 85.012  1.00 5.15  ? 73   LYS A CD  1 
ATOM   486   C CE  . LYS A 1 94  ? 128.358 106.876 85.123  1.00 5.15  ? 73   LYS A CE  1 
ATOM   487   N NZ  . LYS A 1 94  ? 128.609 107.496 83.793  1.00 5.15  ? 73   LYS A NZ  1 
ATOM   488   N N   . TRP A 1 95  ? 123.154 104.409 85.643  1.00 2.90  ? 74   TRP A N   1 
ATOM   489   C CA  . TRP A 1 95  ? 121.944 105.090 86.101  1.00 2.90  ? 74   TRP A CA  1 
ATOM   490   C C   . TRP A 1 95  ? 121.625 104.851 87.571  1.00 2.90  ? 74   TRP A C   1 
ATOM   491   O O   . TRP A 1 95  ? 120.878 105.633 88.167  1.00 2.90  ? 74   TRP A O   1 
ATOM   492   C CB  . TRP A 1 95  ? 120.777 104.624 85.220  1.00 2.90  ? 74   TRP A CB  1 
ATOM   493   C CG  . TRP A 1 95  ? 119.399 104.922 85.723  1.00 2.90  ? 74   TRP A CG  1 
ATOM   494   C CD1 . TRP A 1 95  ? 118.613 104.109 86.479  1.00 2.90  ? 74   TRP A CD1 1 
ATOM   495   C CD2 . TRP A 1 95  ? 118.626 106.100 85.471  1.00 2.90  ? 74   TRP A CD2 1 
ATOM   496   N NE1 . TRP A 1 95  ? 117.410 104.712 86.732  1.00 2.90  ? 74   TRP A NE1 1 
ATOM   497   C CE2 . TRP A 1 95  ? 117.393 105.937 86.123  1.00 2.90  ? 74   TRP A CE2 1 
ATOM   498   C CE3 . TRP A 1 95  ? 118.862 107.281 84.765  1.00 2.90  ? 74   TRP A CE3 1 
ATOM   499   C CZ2 . TRP A 1 95  ? 116.402 106.906 86.090  1.00 2.90  ? 74   TRP A CZ2 1 
ATOM   500   C CZ3 . TRP A 1 95  ? 117.878 108.238 84.734  1.00 2.90  ? 74   TRP A CZ3 1 
ATOM   501   C CH2 . TRP A 1 95  ? 116.663 108.047 85.391  1.00 2.90  ? 74   TRP A CH2 1 
ATOM   502   N N   . GLY A 1 96  ? 122.162 103.790 88.171  1.00 3.76  ? 75   GLY A N   1 
ATOM   503   C CA  . GLY A 1 96  ? 121.837 103.497 89.556  1.00 3.76  ? 75   GLY A CA  1 
ATOM   504   C C   . GLY A 1 96  ? 122.284 104.584 90.512  1.00 3.76  ? 75   GLY A C   1 
ATOM   505   O O   . GLY A 1 96  ? 121.591 104.890 91.485  1.00 3.76  ? 75   GLY A O   1 
ATOM   506   N N   . ALA A 1 97  ? 123.443 105.187 90.248  1.00 5.38  ? 76   ALA A N   1 
ATOM   507   C CA  . ALA A 1 97  ? 124.013 106.212 91.110  1.00 5.38  ? 76   ALA A CA  1 
ATOM   508   C C   . ALA A 1 97  ? 123.685 107.625 90.649  1.00 5.38  ? 76   ALA A C   1 
ATOM   509   O O   . ALA A 1 97  ? 124.224 108.585 91.206  1.00 5.38  ? 76   ALA A O   1 
ATOM   510   C CB  . ALA A 1 97  ? 125.527 106.038 91.208  1.00 5.38  ? 76   ALA A CB  1 
ATOM   511   N N   . THR A 1 98  ? 122.835 107.774 89.638  1.00 6.57  ? 77   THR A N   1 
ATOM   512   C CA  . THR A 1 98  ? 122.309 109.084 89.287  1.00 6.57  ? 77   THR A CA  1 
ATOM   513   C C   . THR A 1 98  ? 121.518 109.643 90.461  1.00 6.57  ? 77   THR A C   1 
ATOM   514   O O   . THR A 1 98  ? 120.682 108.949 91.044  1.00 6.57  ? 77   THR A O   1 
ATOM   515   C CB  . THR A 1 98  ? 121.423 108.977 88.046  1.00 6.57  ? 77   THR A CB  1 
ATOM   516   O OG1 . THR A 1 98  ? 122.176 108.410 86.969  1.00 6.57  ? 77   THR A OG1 1 
ATOM   517   C CG2 . THR A 1 98  ? 120.929 110.335 87.622  1.00 6.57  ? 77   THR A CG2 1 
ATOM   518   N N   . SER A 1 99  ? 121.783 110.897 90.810  1.00 1.36  ? 78   SER A N   1 
ATOM   519   C CA  . SER A 1 99  ? 121.228 111.456 92.030  1.00 1.36  ? 78   SER A CA  1 
ATOM   520   C C   . SER A 1 99  ? 119.705 111.529 91.941  1.00 1.36  ? 78   SER A C   1 
ATOM   521   O O   . SER A 1 99  ? 119.145 111.637 90.847  1.00 1.36  ? 78   SER A O   1 
ATOM   522   C CB  . SER A 1 99  ? 121.809 112.844 92.291  1.00 1.36  ? 78   SER A CB  1 
ATOM   523   O OG  . SER A 1 99  ? 121.557 113.718 91.210  1.00 1.36  ? 78   SER A OG  1 
ATOM   524   N N   . PRO A 1 100 ? 119.008 111.460 93.076  1.00 4.11  ? 79   PRO A N   1 
ATOM   525   C CA  . PRO A 1 100 ? 117.540 111.515 93.032  1.00 4.11  ? 79   PRO A CA  1 
ATOM   526   C C   . PRO A 1 100 ? 117.002 112.765 92.366  1.00 4.11  ? 79   PRO A C   1 
ATOM   527   O O   . PRO A 1 100 ? 115.918 112.723 91.775  1.00 4.11  ? 79   PRO A O   1 
ATOM   528   C CB  . PRO A 1 100 ? 117.143 111.455 94.513  1.00 4.11  ? 79   PRO A CB  1 
ATOM   529   C CG  . PRO A 1 100 ? 118.304 110.882 95.203  1.00 4.11  ? 79   PRO A CG  1 
ATOM   530   C CD  . PRO A 1 100 ? 119.511 111.304 94.448  1.00 4.11  ? 79   PRO A CD  1 
ATOM   531   N N   . ALA A 1 101 ? 117.722 113.882 92.444  1.00 1.74  ? 80   ALA A N   1 
ATOM   532   C CA  . ALA A 1 101 ? 117.271 115.109 91.808  1.00 1.74  ? 80   ALA A CA  1 
ATOM   533   C C   . ALA A 1 101 ? 117.445 115.090 90.298  1.00 1.74  ? 80   ALA A C   1 
ATOM   534   O O   . ALA A 1 101 ? 116.696 115.777 89.601  1.00 1.74  ? 80   ALA A O   1 
ATOM   535   C CB  . ALA A 1 101 ? 118.012 116.306 92.397  1.00 1.74  ? 80   ALA A CB  1 
ATOM   536   N N   . GLU A 1 102 ? 118.412 114.336 89.776  1.00 4.57  ? 81   GLU A N   1 
ATOM   537   C CA  . GLU A 1 102 ? 118.550 114.225 88.328  1.00 4.57  ? 81   GLU A CA  1 
ATOM   538   C C   . GLU A 1 102 ? 117.476 113.328 87.728  1.00 4.57  ? 81   GLU A C   1 
ATOM   539   O O   . GLU A 1 102 ? 116.894 113.659 86.688  1.00 4.57  ? 81   GLU A O   1 
ATOM   540   C CB  . GLU A 1 102 ? 119.933 113.696 87.967  1.00 4.57  ? 81   GLU A CB  1 
ATOM   541   C CG  . GLU A 1 102 ? 120.988 114.762 87.818  1.00 4.57  ? 81   GLU A CG  1 
ATOM   542   C CD  . GLU A 1 102 ? 122.388 114.220 88.008  1.00 4.57  ? 81   GLU A CD  1 
ATOM   543   O OE1 . GLU A 1 102 ? 123.284 114.605 87.233  1.00 4.57  ? 81   GLU A OE1 1 
ATOM   544   O OE2 . GLU A 1 102 ? 122.593 113.408 88.933  1.00 4.57  ? 81   GLU A OE2 1 
ATOM   545   N N   . ARG A 1 103 ? 117.201 112.190 88.368  1.00 2.17  ? 82   ARG A N   1 
ATOM   546   C CA  . ARG A 1 103 ? 116.170 111.292 87.864  1.00 2.17  ? 82   ARG A CA  1 
ATOM   547   C C   . ARG A 1 103 ? 114.790 111.925 87.966  1.00 2.17  ? 82   ARG A C   1 
ATOM   548   O O   . ARG A 1 103 ? 113.950 111.734 87.083  1.00 2.17  ? 82   ARG A O   1 
ATOM   549   C CB  . ARG A 1 103 ? 116.206 109.966 88.617  1.00 2.17  ? 82   ARG A CB  1 
ATOM   550   C CG  . ARG A 1 103 ? 117.586 109.374 88.770  1.00 2.17  ? 82   ARG A CG  1 
ATOM   551   C CD  . ARG A 1 103 ? 117.510 107.943 89.252  1.00 2.17  ? 82   ARG A CD  1 
ATOM   552   N NE  . ARG A 1 103 ? 116.949 107.843 90.590  1.00 2.17  ? 82   ARG A NE  1 
ATOM   553   C CZ  . ARG A 1 103 ? 117.646 107.497 91.662  1.00 2.17  ? 82   ARG A CZ  1 
ATOM   554   N NH1 . ARG A 1 103 ? 118.932 107.218 91.547  1.00 2.17  ? 82   ARG A NH1 1 
ATOM   555   N NH2 . ARG A 1 103 ? 117.057 107.425 92.843  1.00 2.17  ? 82   ARG A NH2 1 
ATOM   556   N N   . ALA A 1 104 ? 114.532 112.677 89.035  1.00 1.63  ? 83   ALA A N   1 
ATOM   557   C CA  . ALA A 1 104 ? 113.259 113.377 89.130  1.00 1.63  ? 83   ALA A CA  1 
ATOM   558   C C   . ALA A 1 104 ? 113.138 114.465 88.074  1.00 1.63  ? 83   ALA A C   1 
ATOM   559   O O   . ALA A 1 104 ? 112.040 114.711 87.570  1.00 1.63  ? 83   ALA A O   1 
ATOM   560   C CB  . ALA A 1 104 ? 113.078 113.964 90.522  1.00 1.63  ? 83   ALA A CB  1 
ATOM   561   N N   . ASN A 1 105 ? 114.245 115.116 87.714  1.00 1.50  ? 84   ASN A N   1 
ATOM   562   C CA  . ASN A 1 105 ? 114.207 116.068 86.608  1.00 1.50  ? 84   ASN A CA  1 
ATOM   563   C C   . ASN A 1 105 ? 113.897 115.370 85.292  1.00 1.50  ? 84   ASN A C   1 
ATOM   564   O O   . ASN A 1 105 ? 113.116 115.880 84.480  1.00 1.50  ? 84   ASN A O   1 
ATOM   565   C CB  . ASN A 1 105 ? 115.528 116.822 86.513  1.00 1.50  ? 84   ASN A CB  1 
ATOM   566   C CG  . ASN A 1 105 ? 115.679 117.861 87.592  1.00 1.50  ? 84   ASN A CG  1 
ATOM   567   O OD1 . ASN A 1 105 ? 114.760 118.096 88.373  1.00 1.50  ? 84   ASN A OD1 1 
ATOM   568   N ND2 . ASN A 1 105 ? 116.845 118.488 87.649  1.00 1.50  ? 84   ASN A ND2 1 
ATOM   569   N N   . ILE A 1 106 ? 114.497 114.203 85.061  1.00 1.43  ? 85   ILE A N   1 
ATOM   570   C CA  . ILE A 1 106 ? 114.201 113.457 83.842  1.00 1.43  ? 85   ILE A CA  1 
ATOM   571   C C   . ILE A 1 106 ? 112.736 113.044 83.810  1.00 1.43  ? 85   ILE A C   1 
ATOM   572   O O   . ILE A 1 106 ? 112.079 113.109 82.767  1.00 1.43  ? 85   ILE A O   1 
ATOM   573   C CB  . ILE A 1 106 ? 115.133 112.242 83.719  1.00 1.43  ? 85   ILE A CB  1 
ATOM   574   C CG1 . ILE A 1 106 ? 116.551 112.703 83.403  1.00 1.43  ? 85   ILE A CG1 1 
ATOM   575   C CG2 . ILE A 1 106 ? 114.629 111.307 82.657  1.00 1.43  ? 85   ILE A CG2 1 
ATOM   576   C CD1 . ILE A 1 106 ? 117.592 111.640 83.600  1.00 1.43  ? 85   ILE A CD1 1 
ATOM   577   N N   . MET A 1 107 ? 112.200 112.616 84.951  1.00 1.25  ? 86   MET A N   1 
ATOM   578   C CA  . MET A 1 107 ? 110.796 112.226 85.000  1.00 1.25  ? 86   MET A CA  1 
ATOM   579   C C   . MET A 1 107 ? 109.878 113.416 84.765  1.00 1.25  ? 86   MET A C   1 
ATOM   580   O O   . MET A 1 107 ? 108.850 113.288 84.092  1.00 1.25  ? 86   MET A O   1 
ATOM   581   C CB  . MET A 1 107 ? 110.484 111.566 86.339  1.00 1.25  ? 86   MET A CB  1 
ATOM   582   C CG  . MET A 1 107 ? 111.174 110.239 86.542  1.00 1.25  ? 86   MET A CG  1 
ATOM   583   S SD  . MET A 1 107 ? 110.819 109.577 88.165  1.00 1.25  ? 86   MET A SD  1 
ATOM   584   C CE  . MET A 1 107 ? 109.099 109.151 87.960  1.00 1.25  ? 86   MET A CE  1 
ATOM   585   N N   . LEU A 1 108 ? 110.217 114.575 85.328  1.00 1.12  ? 87   LEU A N   1 
ATOM   586   C CA  . LEU A 1 108 ? 109.420 115.772 85.097  1.00 1.12  ? 87   LEU A CA  1 
ATOM   587   C C   . LEU A 1 108 ? 109.429 116.158 83.628  1.00 1.12  ? 87   LEU A C   1 
ATOM   588   O O   . LEU A 1 108 ? 108.394 116.538 83.070  1.00 1.12  ? 87   LEU A O   1 
ATOM   589   C CB  . LEU A 1 108 ? 109.947 116.913 85.956  1.00 1.12  ? 87   LEU A CB  1 
ATOM   590   C CG  . LEU A 1 108 ? 109.422 116.828 87.382  1.00 1.12  ? 87   LEU A CG  1 
ATOM   591   C CD1 . LEU A 1 108 ? 109.894 118.005 88.195  1.00 1.12  ? 87   LEU A CD1 1 
ATOM   592   C CD2 . LEU A 1 108 ? 107.914 116.737 87.370  1.00 1.12  ? 87   LEU A CD2 1 
ATOM   593   N N   . LYS A 1 109 ? 110.587 116.053 82.983  1.00 1.22  ? 88   LYS A N   1 
ATOM   594   C CA  . LYS A 1 109 ? 110.656 116.338 81.557  1.00 1.22  ? 88   LYS A CA  1 
ATOM   595   C C   . LYS A 1 109 ? 109.852 115.326 80.749  1.00 1.22  ? 88   LYS A C   1 
ATOM   596   O O   . LYS A 1 109 ? 109.217 115.688 79.753  1.00 1.22  ? 88   LYS A O   1 
ATOM   597   C CB  . LYS A 1 109 ? 112.112 116.373 81.110  1.00 1.22  ? 88   LYS A CB  1 
ATOM   598   C CG  . LYS A 1 109 ? 112.879 117.558 81.669  1.00 1.22  ? 88   LYS A CG  1 
ATOM   599   C CD  . LYS A 1 109 ? 114.376 117.297 81.705  1.00 1.22  ? 88   LYS A CD  1 
ATOM   600   C CE  . LYS A 1 109 ? 114.867 116.656 80.416  1.00 1.22  ? 88   LYS A CE  1 
ATOM   601   N NZ  . LYS A 1 109 ? 114.586 117.515 79.237  1.00 1.22  ? 88   LYS A NZ  1 
ATOM   602   N N   . ILE A 1 110 ? 109.856 114.059 81.164  1.00 1.43  ? 89   ILE A N   1 
ATOM   603   C CA  . ILE A 1 110 ? 109.040 113.048 80.491  1.00 1.43  ? 89   ILE A CA  1 
ATOM   604   C C   . ILE A 1 110 ? 107.562 113.401 80.600  1.00 1.43  ? 89   ILE A C   1 
ATOM   605   O O   . ILE A 1 110 ? 106.813 113.348 79.616  1.00 1.43  ? 89   ILE A O   1 
ATOM   606   C CB  . ILE A 1 110 ? 109.327 111.652 81.074  1.00 1.43  ? 89   ILE A CB  1 
ATOM   607   C CG1 . ILE A 1 110 ? 110.595 111.063 80.465  1.00 1.43  ? 89   ILE A CG1 1 
ATOM   608   C CG2 . ILE A 1 110 ? 108.165 110.721 80.823  1.00 1.43  ? 89   ILE A CG2 1 
ATOM   609   C CD1 . ILE A 1 110 ? 111.191 109.957 81.276  1.00 1.43  ? 89   ILE A CD1 1 
ATOM   610   N N   . ALA A 1 111 ? 107.121 113.762 81.804  1.00 1.44  ? 90   ALA A N   1 
ATOM   611   C CA  . ALA A 1 111 ? 105.723 114.122 81.999  1.00 1.44  ? 90   ALA A CA  1 
ATOM   612   C C   . ALA A 1 111 ? 105.346 115.340 81.167  1.00 1.44  ? 90   ALA A C   1 
ATOM   613   O O   . ALA A 1 111 ? 104.253 115.396 80.597  1.00 1.44  ? 90   ALA A O   1 
ATOM   614   C CB  . ALA A 1 111 ? 105.450 114.376 83.477  1.00 1.44  ? 90   ALA A CB  1 
ATOM   615   N N   . ASP A 1 112 ? 106.238 116.328 81.086  1.00 1.86  ? 91   ASP A N   1 
ATOM   616   C CA  . ASP A 1 112 ? 105.952 117.515 80.286  1.00 1.86  ? 91   ASP A CA  1 
ATOM   617   C C   . ASP A 1 112 ? 105.858 117.177 78.804  1.00 1.86  ? 91   ASP A C   1 
ATOM   618   O O   . ASP A 1 112 ? 104.965 117.671 78.101  1.00 1.86  ? 91   ASP A O   1 
ATOM   619   C CB  . ASP A 1 112 ? 107.021 118.576 80.533  1.00 1.86  ? 91   ASP A CB  1 
ATOM   620   C CG  . ASP A 1 112 ? 106.981 119.118 81.950  1.00 1.86  ? 91   ASP A CG  1 
ATOM   621   O OD1 . ASP A 1 112 ? 105.991 118.846 82.664  1.00 1.86  ? 91   ASP A OD1 1 
ATOM   622   O OD2 . ASP A 1 112 ? 107.939 119.811 82.354  1.00 1.86  ? 91   ASP A OD2 1 
ATOM   623   N N   . ARG A 1 113 ? 106.761 116.332 78.311  1.00 2.00  ? 92   ARG A N   1 
ATOM   624   C CA  . ARG A 1 113 ? 106.691 115.924 76.915  1.00 2.00  ? 92   ARG A CA  1 
ATOM   625   C C   . ARG A 1 113 ? 105.387 115.198 76.624  1.00 2.00  ? 92   ARG A C   1 
ATOM   626   O O   . ARG A 1 113 ? 104.768 115.417 75.578  1.00 2.00  ? 92   ARG A O   1 
ATOM   627   C CB  . ARG A 1 113 ? 107.884 115.044 76.563  1.00 2.00  ? 92   ARG A CB  1 
ATOM   628   C CG  . ARG A 1 113 ? 107.840 114.523 75.147  1.00 2.00  ? 92   ARG A CG  1 
ATOM   629   C CD  . ARG A 1 113 ? 109.189 114.017 74.705  1.00 2.00  ? 92   ARG A CD  1 
ATOM   630   N NE  . ARG A 1 113 ? 110.220 115.026 74.891  1.00 2.00  ? 92   ARG A NE  1 
ATOM   631   C CZ  . ARG A 1 113 ? 111.487 114.868 74.533  1.00 2.00  ? 92   ARG A CZ  1 
ATOM   632   N NH1 . ARG A 1 113 ? 111.878 113.738 73.965  1.00 2.00  ? 92   ARG A NH1 1 
ATOM   633   N NH2 . ARG A 1 113 ? 112.360 115.841 74.739  1.00 2.00  ? 92   ARG A NH2 1 
ATOM   634   N N   . MET A 1 114 ? 104.953 114.327 77.535  1.00 2.33  ? 93   MET A N   1 
ATOM   635   C CA  . MET A 1 114 ? 103.691 113.626 77.325  1.00 2.33  ? 93   MET A CA  1 
ATOM   636   C C   . MET A 1 114 ? 102.509 114.587 77.360  1.00 2.33  ? 93   MET A C   1 
ATOM   637   O O   . MET A 1 114 ? 101.583 114.466 76.553  1.00 2.33  ? 93   MET A O   1 
ATOM   638   C CB  . MET A 1 114 ? 103.517 112.523 78.367  1.00 2.33  ? 93   MET A CB  1 
ATOM   639   C CG  . MET A 1 114 ? 104.504 111.386 78.234  1.00 2.33  ? 93   MET A CG  1 
ATOM   640   S SD  . MET A 1 114 ? 104.500 110.254 79.630  1.00 2.33  ? 93   MET A SD  1 
ATOM   641   C CE  . MET A 1 114 ? 102.791 110.329 80.138  1.00 2.33  ? 93   MET A CE  1 
ATOM   642   N N   . GLU A 1 115 ? 102.519 115.547 78.287  1.00 2.41  ? 94   GLU A N   1 
ATOM   643   C CA  . GLU A 1 115 ? 101.410 116.490 78.381  1.00 2.41  ? 94   GLU A CA  1 
ATOM   644   C C   . GLU A 1 115 ? 101.327 117.392 77.161  1.00 2.41  ? 94   GLU A C   1 
ATOM   645   O O   . GLU A 1 115 ? 100.241 117.876 76.826  1.00 2.41  ? 94   GLU A O   1 
ATOM   646   C CB  . GLU A 1 115 ? 101.529 117.339 79.644  1.00 2.41  ? 94   GLU A CB  1 
ATOM   647   C CG  . GLU A 1 115 ? 100.197 117.869 80.133  1.00 2.41  ? 94   GLU A CG  1 
ATOM   648   C CD  . GLU A 1 115 ? 100.307 118.664 81.418  1.00 2.41  ? 94   GLU A CD  1 
ATOM   649   O OE1 . GLU A 1 115 ? 100.322 119.910 81.353  1.00 2.41  ? 94   GLU A OE1 1 
ATOM   650   O OE2 . GLU A 1 115 ? 100.369 118.042 82.496  1.00 2.41  ? 94   GLU A OE2 1 
ATOM   651   N N   . ARG A 1 116 ? 102.450 117.644 76.495  1.00 2.24  ? 95   ARG A N   1 
ATOM   652   C CA  . ARG A 1 116 ? 102.395 118.433 75.273  1.00 2.24  ? 95   ARG A CA  1 
ATOM   653   C C   . ARG A 1 116 ? 102.024 117.606 74.050  1.00 2.24  ? 95   ARG A C   1 
ATOM   654   O O   . ARG A 1 116 ? 101.840 118.177 72.972  1.00 2.24  ? 95   ARG A O   1 
ATOM   655   C CB  . ARG A 1 116 ? 103.731 119.130 75.040  1.00 2.24  ? 95   ARG A CB  1 
ATOM   656   C CG  . ARG A 1 116 ? 103.865 120.431 75.796  1.00 2.24  ? 95   ARG A CG  1 
ATOM   657   C CD  . ARG A 1 116 ? 105.106 121.175 75.365  1.00 2.24  ? 95   ARG A CD  1 
ATOM   658   N NE  . ARG A 1 116 ? 106.280 120.311 75.392  1.00 2.24  ? 95   ARG A NE  1 
ATOM   659   C CZ  . ARG A 1 116 ? 107.207 120.348 76.340  1.00 2.24  ? 95   ARG A CZ  1 
ATOM   660   N NH1 . ARG A 1 116 ? 107.098 121.211 77.339  1.00 2.24  ? 95   ARG A NH1 1 
ATOM   661   N NH2 . ARG A 1 116 ? 108.245 119.526 76.288  1.00 2.24  ? 95   ARG A NH2 1 
ATOM   662   N N   . ASN A 1 117 ? 101.916 116.287 74.188  1.00 4.14  ? 96   ASN A N   1 
ATOM   663   C CA  . ASN A 1 117 ? 101.507 115.387 73.116  1.00 4.14  ? 96   ASN A CA  1 
ATOM   664   C C   . ASN A 1 117 ? 100.370 114.493 73.575  1.00 4.14  ? 96   ASN A C   1 
ATOM   665   O O   . ASN A 1 117 ? 100.303 113.316 73.219  1.00 4.14  ? 96   ASN A O   1 
ATOM   666   C CB  . ASN A 1 117 ? 102.672 114.533 72.631  1.00 4.14  ? 96   ASN A CB  1 
ATOM   667   C CG  . ASN A 1 117 ? 103.794 115.353 72.064  1.00 4.14  ? 96   ASN A CG  1 
ATOM   668   O OD1 . ASN A 1 117 ? 104.333 116.229 72.732  1.00 4.14  ? 96   ASN A OD1 1 
ATOM   669   N ND2 . ASN A 1 117 ? 104.161 115.071 70.823  1.00 4.14  ? 96   ASN A ND2 1 
ATOM   670   N N   . LEU A 1 118 ? 99.459  115.034 74.380  1.00 4.46  ? 97   LEU A N   1 
ATOM   671   C CA  . LEU A 1 118 ? 98.397  114.210 74.944  1.00 4.46  ? 97   LEU A CA  1 
ATOM   672   C C   . LEU A 1 118 ? 97.477  113.671 73.853  1.00 4.46  ? 97   LEU A C   1 
ATOM   673   O O   . LEU A 1 118 ? 97.022  112.525 73.930  1.00 4.46  ? 97   LEU A O   1 
ATOM   674   C CB  . LEU A 1 118 ? 97.618  115.017 75.984  1.00 4.46  ? 97   LEU A CB  1 
ATOM   675   C CG  . LEU A 1 118 ? 96.622  114.313 76.906  1.00 4.46  ? 97   LEU A CG  1 
ATOM   676   C CD1 . LEU A 1 118 ? 96.505  115.069 78.211  1.00 4.46  ? 97   LEU A CD1 1 
ATOM   677   C CD2 . LEU A 1 118 ? 95.259  114.181 76.266  1.00 4.46  ? 97   LEU A CD2 1 
ATOM   678   N N   . GLU A 1 119 ? 97.200  114.477 72.827  1.00 7.04  ? 98   GLU A N   1 
ATOM   679   C CA  . GLU A 1 119 ? 96.300  114.052 71.758  1.00 7.04  ? 98   GLU A CA  1 
ATOM   680   C C   . GLU A 1 119 ? 96.852  112.850 71.002  1.00 7.04  ? 98   GLU A C   1 
ATOM   681   O O   . GLU A 1 119 ? 96.123  111.893 70.723  1.00 7.04  ? 98   GLU A O   1 
ATOM   682   C CB  . GLU A 1 119 ? 96.043  115.221 70.806  1.00 7.04  ? 98   GLU A CB  1 
ATOM   683   C CG  . GLU A 1 119 ? 94.992  114.962 69.733  1.00 7.04  ? 98   GLU A CG  1 
ATOM   684   C CD  . GLU A 1 119 ? 95.573  114.344 68.474  1.00 7.04  ? 98   GLU A CD  1 
ATOM   685   O OE1 . GLU A 1 119 ? 96.756  114.606 68.173  1.00 7.04  ? 98   GLU A OE1 1 
ATOM   686   O OE2 . GLU A 1 119 ? 94.847  113.601 67.782  1.00 7.04  ? 98   GLU A OE2 1 
ATOM   687   N N   . LEU A 1 120 ? 98.137  112.885 70.653  1.00 6.00  ? 99   LEU A N   1 
ATOM   688   C CA  . LEU A 1 120 ? 98.739  111.789 69.899  1.00 6.00  ? 99   LEU A CA  1 
ATOM   689   C C   . LEU A 1 120 ? 98.716  110.489 70.695  1.00 6.00  ? 99   LEU A C   1 
ATOM   690   O O   . LEU A 1 120 ? 98.341  109.430 70.175  1.00 6.00  ? 99   LEU A O   1 
ATOM   691   C CB  . LEU A 1 120 ? 100.164 112.172 69.502  1.00 6.00  ? 99   LEU A CB  1 
ATOM   692   C CG  . LEU A 1 120 ? 101.086 111.164 68.833  1.00 6.00  ? 99   LEU A CG  1 
ATOM   693   C CD1 . LEU A 1 120 ? 101.923 111.844 67.774  1.00 6.00  ? 99   LEU A CD1 1 
ATOM   694   C CD2 . LEU A 1 120 ? 101.998 110.576 69.882  1.00 6.00  ? 99   LEU A CD2 1 
ATOM   695   N N   . LEU A 1 121 ? 99.099  110.556 71.970  1.00 5.26  ? 100  LEU A N   1 
ATOM   696   C CA  . LEU A 1 121 ? 99.100  109.362 72.804  1.00 5.26  ? 100  LEU A CA  1 
ATOM   697   C C   . LEU A 1 121 ? 97.692  108.822 72.995  1.00 5.26  ? 100  LEU A C   1 
ATOM   698   O O   . LEU A 1 121 ? 97.467  107.608 72.923  1.00 5.26  ? 100  LEU A O   1 
ATOM   699   C CB  . LEU A 1 121 ? 99.736  109.669 74.157  1.00 5.26  ? 100  LEU A CB  1 
ATOM   700   C CG  . LEU A 1 121 ? 101.171 110.182 74.172  1.00 5.26  ? 100  LEU A CG  1 
ATOM   701   C CD1 . LEU A 1 121 ? 101.573 110.503 75.586  1.00 5.26  ? 100  LEU A CD1 1 
ATOM   702   C CD2 . LEU A 1 121 ? 102.098 109.157 73.579  1.00 5.26  ? 100  LEU A CD2 1 
ATOM   703   N N   . ALA A 1 122 ? 96.730  109.709 73.245  1.00 6.37  ? 101  ALA A N   1 
ATOM   704   C CA  . ALA A 1 122 ? 95.358  109.269 73.459  1.00 6.37  ? 101  ALA A CA  1 
ATOM   705   C C   . ALA A 1 122 ? 94.774  108.640 72.202  1.00 6.37  ? 101  ALA A C   1 
ATOM   706   O O   . ALA A 1 122 ? 94.023  107.661 72.281  1.00 6.37  ? 101  ALA A O   1 
ATOM   707   C CB  . ALA A 1 122 ? 94.508  110.446 73.922  1.00 6.37  ? 101  ALA A CB  1 
ATOM   708   N N   . THR A 1 123 ? 95.103  109.188 71.032  1.00 9.19  ? 102  THR A N   1 
ATOM   709   C CA  . THR A 1 123 ? 94.657  108.584 69.782  1.00 9.19  ? 102  THR A CA  1 
ATOM   710   C C   . THR A 1 123 ? 95.276  107.207 69.583  1.00 9.19  ? 102  THR A C   1 
ATOM   711   O O   . THR A 1 123 ? 94.596  106.271 69.144  1.00 9.19  ? 102  THR A O   1 
ATOM   712   C CB  . THR A 1 123 ? 94.996  109.503 68.614  1.00 9.19  ? 102  THR A CB  1 
ATOM   713   O OG1 . THR A 1 123 ? 94.125  110.639 68.641  1.00 9.19  ? 102  THR A OG1 1 
ATOM   714   C CG2 . THR A 1 123 ? 94.819  108.780 67.303  1.00 9.19  ? 102  THR A CG2 1 
ATOM   715   N N   . ALA A 1 124 ? 96.561  107.060 69.911  1.00 9.00  ? 103  ALA A N   1 
ATOM   716   C CA  . ALA A 1 124 ? 97.184  105.744 69.822  1.00 9.00  ? 103  ALA A CA  1 
ATOM   717   C C   . ALA A 1 124 ? 96.497  104.751 70.748  1.00 9.00  ? 103  ALA A C   1 
ATOM   718   O O   . ALA A 1 124 ? 96.285  103.589 70.385  1.00 9.00  ? 103  ALA A O   1 
ATOM   719   C CB  . ALA A 1 124 ? 98.672  105.842 70.147  1.00 9.00  ? 103  ALA A CB  1 
ATOM   720   N N   . GLU A 1 125 ? 96.127  105.195 71.944  1.00 8.94  ? 104  GLU A N   1 
ATOM   721   C CA  . GLU A 1 125 ? 95.486  104.285 72.885  1.00 8.94  ? 104  GLU A CA  1 
ATOM   722   C C   . GLU A 1 125 ? 94.098  103.882 72.406  1.00 8.94  ? 104  GLU A C   1 
ATOM   723   O O   . GLU A 1 125 ? 93.724  102.708 72.484  1.00 8.94  ? 104  GLU A O   1 
ATOM   724   C CB  . GLU A 1 125 ? 95.433  104.917 74.268  1.00 8.94  ? 104  GLU A CB  1 
ATOM   725   C CG  . GLU A 1 125 ? 96.817  105.086 74.804  1.00 8.94  ? 104  GLU A CG  1 
ATOM   726   C CD  . GLU A 1 125 ? 97.480  103.756 75.057  1.00 8.94  ? 104  GLU A CD  1 
ATOM   727   O OE1 . GLU A 1 125 ? 96.770  102.788 75.403  1.00 8.94  ? 104  GLU A OE1 1 
ATOM   728   O OE2 . GLU A 1 125 ? 98.708  103.667 74.856  1.00 8.94  ? 104  GLU A OE2 1 
ATOM   729   N N   . THR A 1 126 ? 93.319  104.844 71.909  1.00 9.42  ? 105  THR A N   1 
ATOM   730   C CA  . THR A 1 126 ? 92.012  104.521 71.347  1.00 9.42  ? 105  THR A CA  1 
ATOM   731   C C   . THR A 1 126 ? 92.136  103.518 70.213  1.00 9.42  ? 105  THR A C   1 
ATOM   732   O O   . THR A 1 126 ? 91.409  102.521 70.169  1.00 9.42  ? 105  THR A O   1 
ATOM   733   C CB  . THR A 1 126 ? 91.320  105.790 70.858  1.00 9.42  ? 105  THR A CB  1 
ATOM   734   O OG1 . THR A 1 126 ? 90.997  106.621 71.976  1.00 9.42  ? 105  THR A OG1 1 
ATOM   735   C CG2 . THR A 1 126 ? 90.069  105.459 70.070  1.00 9.42  ? 105  THR A CG2 1 
ATOM   736   N N   . TRP A 1 127 ? 93.066  103.757 69.292  1.00 11.53 ? 106  TRP A N   1 
ATOM   737   C CA  . TRP A 1 127 ? 93.197  102.874 68.143  1.00 11.53 ? 106  TRP A CA  1 
ATOM   738   C C   . TRP A 1 127 ? 93.633  101.472 68.552  1.00 11.53 ? 106  TRP A C   1 
ATOM   739   O O   . TRP A 1 127 ? 93.112  100.482 68.031  1.00 11.53 ? 106  TRP A O   1 
ATOM   740   C CB  . TRP A 1 127 ? 94.178  103.472 67.144  1.00 11.53 ? 106  TRP A CB  1 
ATOM   741   C CG  . TRP A 1 127 ? 93.549  104.416 66.190  1.00 11.53 ? 106  TRP A CG  1 
ATOM   742   C CD1 . TRP A 1 127 ? 93.266  105.727 66.405  1.00 11.53 ? 106  TRP A CD1 1 
ATOM   743   C CD2 . TRP A 1 127 ? 93.127  104.127 64.858  1.00 11.53 ? 106  TRP A CD2 1 
ATOM   744   N NE1 . TRP A 1 127 ? 92.689  106.275 65.290  1.00 11.53 ? 106  TRP A NE1 1 
ATOM   745   C CE2 . TRP A 1 127 ? 92.594  105.310 64.324  1.00 11.53 ? 106  TRP A CE2 1 
ATOM   746   C CE3 . TRP A 1 127 ? 93.145  102.978 64.066  1.00 11.53 ? 106  TRP A CE3 1 
ATOM   747   C CZ2 . TRP A 1 127 ? 92.085  105.379 63.036  1.00 11.53 ? 106  TRP A CZ2 1 
ATOM   748   C CZ3 . TRP A 1 127 ? 92.640  103.049 62.793  1.00 11.53 ? 106  TRP A CZ3 1 
ATOM   749   C CH2 . TRP A 1 127 ? 92.118  104.240 62.287  1.00 11.53 ? 106  TRP A CH2 1 
ATOM   750   N N   . ASP A 1 128 ? 94.584  101.361 69.481  1.00 11.38 ? 107  ASP A N   1 
ATOM   751   C CA  . ASP A 1 128 ? 95.145  100.051 69.793  1.00 11.38 ? 107  ASP A CA  1 
ATOM   752   C C   . ASP A 1 128 ? 94.291  99.262  70.776  1.00 11.38 ? 107  ASP A C   1 
ATOM   753   O O   . ASP A 1 128 ? 94.313  98.027  70.752  1.00 11.38 ? 107  ASP A O   1 
ATOM   754   C CB  . ASP A 1 128 ? 96.557  100.208 70.352  1.00 11.38 ? 107  ASP A CB  1 
ATOM   755   C CG  . ASP A 1 128 ? 97.381  98.953  70.209  1.00 11.38 ? 107  ASP A CG  1 
ATOM   756   O OD1 . ASP A 1 128 ? 96.856  97.949  69.684  1.00 11.38 ? 107  ASP A OD1 1 
ATOM   757   O OD2 . ASP A 1 128 ? 98.561  98.970  70.613  1.00 11.38 ? 107  ASP A OD2 1 
ATOM   758   N N   . ASN A 1 129 ? 93.536  99.938  71.640  1.00 9.60  ? 108  ASN A N   1 
ATOM   759   C CA  . ASN A 1 129 ? 92.762  99.272  72.674  1.00 9.60  ? 108  ASN A CA  1 
ATOM   760   C C   . ASN A 1 129 ? 91.272  99.242  72.364  1.00 9.60  ? 108  ASN A C   1 
ATOM   761   O O   . ASN A 1 129 ? 90.568  98.366  72.871  1.00 9.60  ? 108  ASN A O   1 
ATOM   762   C CB  . ASN A 1 129 ? 92.996  99.984  74.018  1.00 9.60  ? 108  ASN A CB  1 
ATOM   763   C CG  . ASN A 1 129 ? 92.415  99.246  75.210  1.00 9.60  ? 108  ASN A CG  1 
ATOM   764   O OD1 . ASN A 1 129 ? 92.534  99.669  76.351  1.00 9.60  ? 108  ASN A OD1 1 
ATOM   765   N ND2 . ASN A 1 129 ? 91.779  98.119  74.935  1.00 9.60  ? 108  ASN A ND2 1 
ATOM   766   N N   . GLY A 1 130 ? 90.783  100.138 71.513  1.00 9.25  ? 109  GLY A N   1 
ATOM   767   C CA  . GLY A 1 130 ? 89.359  100.273 71.306  1.00 9.25  ? 109  GLY A CA  1 
ATOM   768   C C   . GLY A 1 130 ? 88.662  101.118 72.341  1.00 9.25  ? 109  GLY A C   1 
ATOM   769   O O   . GLY A 1 130 ? 87.434  101.228 72.308  1.00 9.25  ? 109  GLY A O   1 
ATOM   770   N N   . LYS A 1 131 ? 89.411  101.714 73.256  1.00 8.61  ? 110  LYS A N   1 
ATOM   771   C CA  . LYS A 1 131 ? 88.846  102.555 74.290  1.00 8.61  ? 110  LYS A CA  1 
ATOM   772   C C   . LYS A 1 131 ? 88.329  103.852 73.668  1.00 8.61  ? 110  LYS A C   1 
ATOM   773   O O   . LYS A 1 131 ? 88.894  104.340 72.691  1.00 8.61  ? 110  LYS A O   1 
ATOM   774   C CB  . LYS A 1 131 ? 89.929  102.849 75.320  1.00 8.61  ? 110  LYS A CB  1 
ATOM   775   C CG  . LYS A 1 131 ? 89.519  103.523 76.600  1.00 8.61  ? 110  LYS A CG  1 
ATOM   776   C CD  . LYS A 1 131 ? 90.776  103.810 77.376  1.00 8.61  ? 110  LYS A CD  1 
ATOM   777   C CE  . LYS A 1 131 ? 91.378  102.541 77.921  1.00 8.61  ? 110  LYS A CE  1 
ATOM   778   N NZ  . LYS A 1 131 ? 92.566  102.851 78.744  1.00 8.61  ? 110  LYS A NZ  1 
ATOM   779   N N   . PRO A 1 132 ? 87.251  104.425 74.201  1.00 9.70  ? 111  PRO A N   1 
ATOM   780   C CA  . PRO A 1 132 ? 86.757  105.690 73.648  1.00 9.70  ? 111  PRO A CA  1 
ATOM   781   C C   . PRO A 1 132 ? 87.795  106.794 73.779  1.00 9.70  ? 111  PRO A C   1 
ATOM   782   O O   . PRO A 1 132 ? 88.506  106.883 74.780  1.00 9.70  ? 111  PRO A O   1 
ATOM   783   C CB  . PRO A 1 132 ? 85.514  105.986 74.494  1.00 9.70  ? 111  PRO A CB  1 
ATOM   784   C CG  . PRO A 1 132 ? 85.130  104.699 75.081  1.00 9.70  ? 111  PRO A CG  1 
ATOM   785   C CD  . PRO A 1 132 ? 86.390  103.939 75.289  1.00 9.70  ? 111  PRO A CD  1 
ATOM   786   N N   . ILE A 1 133 ? 87.872  107.648 72.754  1.00 9.96  ? 112  ILE A N   1 
ATOM   787   C CA  . ILE A 1 133 ? 88.778  108.793 72.817  1.00 9.96  ? 112  ILE A CA  1 
ATOM   788   C C   . ILE A 1 133 ? 88.387  109.705 73.966  1.00 9.96  ? 112  ILE A C   1 
ATOM   789   O O   . ILE A 1 133 ? 89.242  110.352 74.585  1.00 9.96  ? 112  ILE A O   1 
ATOM   790   C CB  . ILE A 1 133 ? 88.795  109.545 71.473  1.00 9.96  ? 112  ILE A CB  1 
ATOM   791   C CG1 . ILE A 1 133 ? 89.941  110.553 71.440  1.00 9.96  ? 112  ILE A CG1 1 
ATOM   792   C CG2 . ILE A 1 133 ? 87.470  110.243 71.217  1.00 9.96  ? 112  ILE A CG2 1 
ATOM   793   C CD1 . ILE A 1 133 ? 91.260  109.985 71.838  1.00 9.96  ? 112  ILE A CD1 1 
ATOM   794   N N   . ARG A 1 134 ? 87.094  109.756 74.276  1.00 11.87 ? 113  ARG A N   1 
ATOM   795   C CA  . ARG A 1 134 ? 86.622  110.447 75.464  1.00 11.87 ? 113  ARG A CA  1 
ATOM   796   C C   . ARG A 1 134 ? 87.321  109.927 76.711  1.00 11.87 ? 113  ARG A C   1 
ATOM   797   O O   . ARG A 1 134 ? 87.913  110.699 77.473  1.00 11.87 ? 113  ARG A O   1 
ATOM   798   C CB  . ARG A 1 134 ? 85.112  110.259 75.564  1.00 11.87 ? 113  ARG A CB  1 
ATOM   799   C CG  . ARG A 1 134 ? 84.426  110.978 76.686  1.00 11.87 ? 113  ARG A CG  1 
ATOM   800   C CD  . ARG A 1 134 ? 83.019  110.436 76.821  1.00 11.87 ? 113  ARG A CD  1 
ATOM   801   N NE  . ARG A 1 134 ? 82.987  109.255 77.675  1.00 11.87 ? 113  ARG A NE  1 
ATOM   802   C CZ  . ARG A 1 134 ? 81.909  108.834 78.322  1.00 11.87 ? 113  ARG A CZ  1 
ATOM   803   N NH1 . ARG A 1 134 ? 80.768  109.496 78.205  1.00 11.87 ? 113  ARG A NH1 1 
ATOM   804   N NH2 . ARG A 1 134 ? 81.969  107.754 79.085  1.00 11.87 ? 113  ARG A NH2 1 
ATOM   805   N N   . GLU A 1 135 ? 87.298  108.607 76.912  1.00 11.31 ? 114  GLU A N   1 
ATOM   806   C CA  . GLU A 1 135 ? 87.882  108.030 78.118  1.00 11.31 ? 114  GLU A CA  1 
ATOM   807   C C   . GLU A 1 135 ? 89.386  108.251 78.170  1.00 11.31 ? 114  GLU A C   1 
ATOM   808   O O   . GLU A 1 135 ? 89.921  108.632 79.217  1.00 11.31 ? 114  GLU A O   1 
ATOM   809   C CB  . GLU A 1 135 ? 87.565  106.539 78.207  1.00 11.31 ? 114  GLU A CB  1 
ATOM   810   C CG  . GLU A 1 135 ? 86.179  106.217 78.732  1.00 11.31 ? 114  GLU A CG  1 
ATOM   811   C CD  . GLU A 1 135 ? 85.842  104.742 78.603  1.00 11.31 ? 114  GLU A CD  1 
ATOM   812   O OE1 . GLU A 1 135 ? 86.782  103.922 78.565  1.00 11.31 ? 114  GLU A OE1 1 
ATOM   813   O OE2 . GLU A 1 135 ? 84.642  104.402 78.540  1.00 11.31 ? 114  GLU A OE2 1 
ATOM   814   N N   . THR A 1 136 ? 90.086  108.031 77.054  1.00 8.20  ? 115  THR A N   1 
ATOM   815   C CA  . THR A 1 136 ? 91.528  108.248 77.053  1.00 8.20  ? 115  THR A CA  1 
ATOM   816   C C   . THR A 1 136 ? 91.850  109.694 77.401  1.00 8.20  ? 115  THR A C   1 
ATOM   817   O O   . THR A 1 136 ? 92.406  109.967 78.468  1.00 8.20  ? 115  THR A O   1 
ATOM   818   C CB  . THR A 1 136 ? 92.145  107.866 75.708  1.00 8.20  ? 115  THR A CB  1 
ATOM   819   O OG1 . THR A 1 136 ? 91.844  108.873 74.740  1.00 8.20  ? 115  THR A OG1 1 
ATOM   820   C CG2 . THR A 1 136 ? 91.630  106.533 75.228  1.00 8.20  ? 115  THR A CG2 1 
ATOM   821   N N   . MET A 1 137 ? 91.421  110.636 76.554  1.00 9.72  ? 116  MET A N   1 
ATOM   822   C CA  . MET A 1 137 ? 91.790  112.034 76.756  1.00 9.72  ? 116  MET A CA  1 
ATOM   823   C C   . MET A 1 137 ? 91.315  112.573 78.099  1.00 9.72  ? 116  MET A C   1 
ATOM   824   O O   . MET A 1 137 ? 91.917  113.510 78.630  1.00 9.72  ? 116  MET A O   1 
ATOM   825   C CB  . MET A 1 137 ? 91.235  112.899 75.624  1.00 9.72  ? 116  MET A CB  1 
ATOM   826   C CG  . MET A 1 137 ? 92.050  112.839 74.351  1.00 9.72  ? 116  MET A CG  1 
ATOM   827   S SD  . MET A 1 137 ? 91.723  114.186 73.207  1.00 9.72  ? 116  MET A SD  1 
ATOM   828   C CE  . MET A 1 137 ? 93.112  115.260 73.552  1.00 9.72  ? 116  MET A CE  1 
ATOM   829   N N   . ALA A 1 138 ? 90.255  112.004 78.672  1.00 8.43  ? 117  ALA A N   1 
ATOM   830   C CA  . ALA A 1 138 ? 89.777  112.521 79.946  1.00 8.43  ? 117  ALA A CA  1 
ATOM   831   C C   . ALA A 1 138 ? 90.565  111.951 81.117  1.00 8.43  ? 117  ALA A C   1 
ATOM   832   O O   . ALA A 1 138 ? 91.083  112.705 81.946  1.00 8.43  ? 117  ALA A O   1 
ATOM   833   C CB  . ALA A 1 138 ? 88.287  112.223 80.106  1.00 8.43  ? 117  ALA A CB  1 
ATOM   834   N N   . ALA A 1 139 ? 90.675  110.625 81.209  1.00 7.04  ? 118  ALA A N   1 
ATOM   835   C CA  . ALA A 1 139 ? 91.214  110.003 82.410  1.00 7.04  ? 118  ALA A CA  1 
ATOM   836   C C   . ALA A 1 139 ? 92.550  109.301 82.227  1.00 7.04  ? 118  ALA A C   1 
ATOM   837   O O   . ALA A 1 139 ? 93.343  109.290 83.164  1.00 7.04  ? 118  ALA A O   1 
ATOM   838   C CB  . ALA A 1 139 ? 90.210  108.993 82.978  1.00 7.04  ? 118  ALA A CB  1 
ATOM   839   N N   . ASP A 1 140 ? 92.838  108.715 81.066  1.00 6.72  ? 119  ASP A N   1 
ATOM   840   C CA  . ASP A 1 140 ? 93.961  107.784 81.016  1.00 6.72  ? 119  ASP A CA  1 
ATOM   841   C C   . ASP A 1 140 ? 95.297  108.492 80.853  1.00 6.72  ? 119  ASP A C   1 
ATOM   842   O O   . ASP A 1 140 ? 96.274  108.129 81.513  1.00 6.72  ? 119  ASP A O   1 
ATOM   843   C CB  . ASP A 1 140 ? 93.766  106.775 79.888  1.00 6.72  ? 119  ASP A CB  1 
ATOM   844   C CG  . ASP A 1 140 ? 92.527  105.933 80.070  1.00 6.72  ? 119  ASP A CG  1 
ATOM   845   O OD1 . ASP A 1 140 ? 91.415  106.497 80.088  1.00 6.72  ? 119  ASP A OD1 1 
ATOM   846   O OD2 . ASP A 1 140 ? 92.665  104.700 80.190  1.00 6.72  ? 119  ASP A OD2 1 
ATOM   847   N N   . LEU A 1 141 ? 95.372  109.483 79.982  1.00 4.36  ? 120  LEU A N   1 
ATOM   848   C CA  . LEU A 1 141 ? 96.649  110.149 79.766  1.00 4.36  ? 120  LEU A CA  1 
ATOM   849   C C   . LEU A 1 141 ? 96.927  111.171 80.862  1.00 4.36  ? 120  LEU A C   1 
ATOM   850   O O   . LEU A 1 141 ? 98.070  111.259 81.332  1.00 4.36  ? 120  LEU A O   1 
ATOM   851   C CB  . LEU A 1 141 ? 96.708  110.800 78.385  1.00 4.36  ? 120  LEU A CB  1 
ATOM   852   C CG  . LEU A 1 141 ? 97.094  109.875 77.238  1.00 4.36  ? 120  LEU A CG  1 
ATOM   853   C CD1 . LEU A 1 141 ? 98.501  109.387 77.471  1.00 4.36  ? 120  LEU A CD1 1 
ATOM   854   C CD2 . LEU A 1 141 ? 96.138  108.705 77.091  1.00 4.36  ? 120  LEU A CD2 1 
ATOM   855   N N   . PRO A 1 142 ? 95.943  111.967 81.294  1.00 4.37  ? 121  PRO A N   1 
ATOM   856   C CA  . PRO A 1 142 ? 96.190  112.806 82.471  1.00 4.37  ? 121  PRO A CA  1 
ATOM   857   C C   . PRO A 1 142 ? 96.656  112.012 83.675  1.00 4.37  ? 121  PRO A C   1 
ATOM   858   O O   . PRO A 1 142 ? 97.528  112.483 84.410  1.00 4.37  ? 121  PRO A O   1 
ATOM   859   C CB  . PRO A 1 142 ? 94.833  113.472 82.715  1.00 4.37  ? 121  PRO A CB  1 
ATOM   860   C CG  . PRO A 1 142 ? 94.188  113.505 81.404  1.00 4.37  ? 121  PRO A CG  1 
ATOM   861   C CD  . PRO A 1 142 ? 94.711  112.371 80.592  1.00 4.37  ? 121  PRO A CD  1 
ATOM   862   N N   . LEU A 1 143 ? 96.121  110.808 83.885  1.00 3.12  ? 122  LEU A N   1 
ATOM   863   C CA  . LEU A 1 143 ? 96.569  109.990 85.006  1.00 3.12  ? 122  LEU A CA  1 
ATOM   864   C C   . LEU A 1 143 ? 98.016  109.544 84.834  1.00 3.12  ? 122  LEU A C   1 
ATOM   865   O O   . LEU A 1 143 ? 98.777  109.522 85.803  1.00 3.12  ? 122  LEU A O   1 
ATOM   866   C CB  . LEU A 1 143 ? 95.649  108.787 85.187  1.00 3.12  ? 122  LEU A CB  1 
ATOM   867   C CG  . LEU A 1 143 ? 94.422  109.054 86.062  1.00 3.12  ? 122  LEU A CG  1 
ATOM   868   C CD1 . LEU A 1 143 ? 93.537  107.827 86.147  1.00 3.12  ? 122  LEU A CD1 1 
ATOM   869   C CD2 . LEU A 1 143 ? 94.831  109.516 87.446  1.00 3.12  ? 122  LEU A CD2 1 
ATOM   870   N N   . ALA A 1 144 ? 98.425  109.200 83.612  1.00 2.88  ? 123  ALA A N   1 
ATOM   871   C CA  . ALA A 1 144 ? 99.812  108.799 83.391  1.00 2.88  ? 123  ALA A CA  1 
ATOM   872   C C   . ALA A 1 144 ? 100.778 109.963 83.605  1.00 2.88  ? 123  ALA A C   1 
ATOM   873   O O   . ALA A 1 144 ? 101.843 109.796 84.221  1.00 2.88  ? 123  ALA A O   1 
ATOM   874   C CB  . ALA A 1 144 ? 99.966  108.224 81.989  1.00 2.88  ? 123  ALA A CB  1 
ATOM   875   N N   . ILE A 1 145 ? 100.426 111.150 83.108  1.00 2.47  ? 124  ILE A N   1 
ATOM   876   C CA  . ILE A 1 145 ? 101.278 112.320 83.313  1.00 2.47  ? 124  ILE A CA  1 
ATOM   877   C C   . ILE A 1 145 ? 101.347 112.671 84.795  1.00 2.47  ? 124  ILE A C   1 
ATOM   878   O O   . ILE A 1 145 ? 102.424 112.948 85.341  1.00 2.47  ? 124  ILE A O   1 
ATOM   879   C CB  . ILE A 1 145 ? 100.774 113.507 82.474  1.00 2.47  ? 124  ILE A CB  1 
ATOM   880   C CG1 . ILE A 1 145 ? 100.697 113.124 81.001  1.00 2.47  ? 124  ILE A CG1 1 
ATOM   881   C CG2 . ILE A 1 145 ? 101.682 114.698 82.645  1.00 2.47  ? 124  ILE A CG2 1 
ATOM   882   C CD1 . ILE A 1 145 ? 99.603  113.827 80.258  1.00 2.47  ? 124  ILE A CD1 1 
ATOM   883   N N   . ASP A 1 146 ? 100.198 112.663 85.468  1.00 2.11  ? 125  ASP A N   1 
ATOM   884   C CA  . ASP A 1 146 ? 100.180 112.927 86.897  1.00 2.11  ? 125  ASP A CA  1 
ATOM   885   C C   . ASP A 1 146 ? 100.962 111.876 87.658  1.00 2.11  ? 125  ASP A C   1 
ATOM   886   O O   . ASP A 1 146 ? 101.520 112.166 88.715  1.00 2.11  ? 125  ASP A O   1 
ATOM   887   C CB  . ASP A 1 146 ? 98.742  112.978 87.398  1.00 2.11  ? 125  ASP A CB  1 
ATOM   888   C CG  . ASP A 1 146 ? 98.599  113.777 88.670  1.00 2.11  ? 125  ASP A CG  1 
ATOM   889   O OD1 . ASP A 1 146 ? 99.227  114.853 88.767  1.00 2.11  ? 125  ASP A OD1 1 
ATOM   890   O OD2 . ASP A 1 146 ? 97.862  113.331 89.575  1.00 2.11  ? 125  ASP A OD2 1 
ATOM   891   N N   . HIS A 1 147 ? 101.046 110.664 87.122  1.00 2.76  ? 126  HIS A N   1 
ATOM   892   C CA  . HIS A 1 147 ? 101.735 109.590 87.819  1.00 2.76  ? 126  HIS A CA  1 
ATOM   893   C C   . HIS A 1 147 ? 103.242 109.773 87.726  1.00 2.76  ? 126  HIS A C   1 
ATOM   894   O O   . HIS A 1 147 ? 103.962 109.593 88.717  1.00 2.76  ? 126  HIS A O   1 
ATOM   895   C CB  . HIS A 1 147 ? 101.295 108.257 87.218  1.00 2.76  ? 126  HIS A CB  1 
ATOM   896   C CG  . HIS A 1 147 ? 101.528 107.081 88.105  1.00 2.76  ? 126  HIS A CG  1 
ATOM   897   N ND1 . HIS A 1 147 ? 100.695 106.778 89.159  1.00 2.76  ? 126  HIS A ND1 1 
ATOM   898   C CD2 . HIS A 1 147 ? 102.485 106.126 88.092  1.00 2.76  ? 126  HIS A CD2 1 
ATOM   899   C CE1 . HIS A 1 147 ? 101.132 105.688 89.761  1.00 2.76  ? 126  HIS A CE1 1 
ATOM   900   N NE2 . HIS A 1 147 ? 102.216 105.272 89.133  1.00 2.76  ? 126  HIS A NE2 1 
ATOM   901   N N   . PHE A 1 148 ? 103.729 110.173 86.551  1.00 1.64  ? 127  PHE A N   1 
ATOM   902   C CA  . PHE A 1 148 ? 105.144 110.510 86.425  1.00 1.64  ? 127  PHE A CA  1 
ATOM   903   C C   . PHE A 1 148 ? 105.516 111.705 87.294  1.00 1.64  ? 127  PHE A C   1 
ATOM   904   O O   . PHE A 1 148 ? 106.561 111.698 87.958  1.00 1.64  ? 127  PHE A O   1 
ATOM   905   C CB  . PHE A 1 148 ? 105.500 110.781 84.969  1.00 1.64  ? 127  PHE A CB  1 
ATOM   906   C CG  . PHE A 1 148 ? 105.964 109.569 84.234  1.00 1.64  ? 127  PHE A CG  1 
ATOM   907   C CD1 . PHE A 1 148 ? 107.231 109.070 84.435  1.00 1.64  ? 127  PHE A CD1 1 
ATOM   908   C CD2 . PHE A 1 148 ? 105.133 108.924 83.345  1.00 1.64  ? 127  PHE A CD2 1 
ATOM   909   C CE1 . PHE A 1 148 ? 107.660 107.949 83.759  1.00 1.64  ? 127  PHE A CE1 1 
ATOM   910   C CE2 . PHE A 1 148 ? 105.557 107.807 82.671  1.00 1.64  ? 127  PHE A CE2 1 
ATOM   911   C CZ  . PHE A 1 148 ? 106.819 107.319 82.878  1.00 1.64  ? 127  PHE A CZ  1 
ATOM   912   N N   . ARG A 1 149 ? 104.681 112.746 87.304  1.00 1.62  ? 128  ARG A N   1 
ATOM   913   C CA  . ARG A 1 149 ? 104.971 113.895 88.160  1.00 1.62  ? 128  ARG A CA  1 
ATOM   914   C C   . ARG A 1 149 ? 104.962 113.503 89.629  1.00 1.62  ? 128  ARG A C   1 
ATOM   915   O O   . ARG A 1 149 ? 105.837 113.919 90.399  1.00 1.62  ? 128  ARG A O   1 
ATOM   916   C CB  . ARG A 1 149 ? 103.966 115.012 87.907  1.00 1.62  ? 128  ARG A CB  1 
ATOM   917   C CG  . ARG A 1 149 ? 103.963 115.502 86.493  1.00 1.62  ? 128  ARG A CG  1 
ATOM   918   C CD  . ARG A 1 149 ? 103.542 116.940 86.417  1.00 1.62  ? 128  ARG A CD  1 
ATOM   919   N NE  . ARG A 1 149 ? 103.748 117.473 85.079  1.00 1.62  ? 128  ARG A NE  1 
ATOM   920   C CZ  . ARG A 1 149 ? 102.768 117.882 84.287  1.00 1.62  ? 128  ARG A CZ  1 
ATOM   921   N NH1 . ARG A 1 149 ? 101.514 117.820 84.702  1.00 1.62  ? 128  ARG A NH1 1 
ATOM   922   N NH2 . ARG A 1 149 ? 103.042 118.352 83.083  1.00 1.62  ? 128  ARG A NH2 1 
ATOM   923   N N   . TYR A 1 150 ? 103.992 112.683 90.030  1.00 3.11  ? 129  TYR A N   1 
ATOM   924   C CA  . TYR A 1 150 ? 103.902 112.241 91.411  1.00 3.11  ? 129  TYR A CA  1 
ATOM   925   C C   . TYR A 1 150 ? 105.136 111.469 91.832  1.00 3.11  ? 129  TYR A C   1 
ATOM   926   O O   . TYR A 1 150 ? 105.637 111.646 92.946  1.00 3.11  ? 129  TYR A O   1 
ATOM   927   C CB  . TYR A 1 150 ? 102.660 111.381 91.597  1.00 3.11  ? 129  TYR A CB  1 
ATOM   928   C CG  . TYR A 1 150 ? 102.571 110.774 92.962  1.00 3.11  ? 129  TYR A CG  1 
ATOM   929   C CD1 . TYR A 1 150 ? 102.222 111.540 94.048  1.00 3.11  ? 129  TYR A CD1 1 
ATOM   930   C CD2 . TYR A 1 150 ? 102.831 109.432 93.162  1.00 3.11  ? 129  TYR A CD2 1 
ATOM   931   C CE1 . TYR A 1 150 ? 102.153 111.002 95.287  1.00 3.11  ? 129  TYR A CE1 1 
ATOM   932   C CE2 . TYR A 1 150 ? 102.757 108.877 94.408  1.00 3.11  ? 129  TYR A CE2 1 
ATOM   933   C CZ  . TYR A 1 150 ? 102.408 109.666 95.467  1.00 3.11  ? 129  TYR A CZ  1 
ATOM   934   O OH  . TYR A 1 150 ? 102.322 109.128 96.724  1.00 3.11  ? 129  TYR A OH  1 
ATOM   935   N N   . PHE A 1 151 ? 105.635 110.592 90.969  1.00 1.78  ? 130  PHE A N   1 
ATOM   936   C CA  . PHE A 1 151 ? 106.757 109.781 91.413  1.00 1.78  ? 130  PHE A CA  1 
ATOM   937   C C   . PHE A 1 151 ? 108.082 110.523 91.331  1.00 1.78  ? 130  PHE A C   1 
ATOM   938   O O   . PHE A 1 151 ? 108.954 110.285 92.170  1.00 1.78  ? 130  PHE A O   1 
ATOM   939   C CB  . PHE A 1 151 ? 106.772 108.459 90.660  1.00 1.78  ? 130  PHE A CB  1 
ATOM   940   C CG  . PHE A 1 151 ? 105.951 107.419 91.339  1.00 1.78  ? 130  PHE A CG  1 
ATOM   941   C CD1 . PHE A 1 151 ? 106.353 106.906 92.553  1.00 1.78  ? 130  PHE A CD1 1 
ATOM   942   C CD2 . PHE A 1 151 ? 104.737 107.024 90.824  1.00 1.78  ? 130  PHE A CD2 1 
ATOM   943   C CE1 . PHE A 1 151 ? 105.592 105.984 93.209  1.00 1.78  ? 130  PHE A CE1 1 
ATOM   944   C CE2 . PHE A 1 151 ? 103.974 106.102 91.481  1.00 1.78  ? 130  PHE A CE2 1 
ATOM   945   C CZ  . PHE A 1 151 ? 104.401 105.581 92.673  1.00 1.78  ? 130  PHE A CZ  1 
ATOM   946   N N   . ALA A 1 152 ? 108.236 111.468 90.401  1.00 2.06  ? 131  ALA A N   1 
ATOM   947   C CA  . ALA A 1 152 ? 109.366 112.387 90.505  1.00 2.06  ? 131  ALA A CA  1 
ATOM   948   C C   . ALA A 1 152 ? 109.332 113.138 91.831  1.00 2.06  ? 131  ALA A C   1 
ATOM   949   O O   . ALA A 1 152 ? 110.361 113.289 92.508  1.00 2.06  ? 131  ALA A O   1 
ATOM   950   C CB  . ALA A 1 152 ? 109.358 113.367 89.336  1.00 2.06  ? 131  ALA A CB  1 
ATOM   951   N N   . GLY A 1 153 ? 108.153 113.592 92.234  1.00 2.03  ? 132  GLY A N   1 
ATOM   952   C CA  . GLY A 1 153 ? 108.022 114.233 93.517  1.00 2.03  ? 132  GLY A CA  1 
ATOM   953   C C   . GLY A 1 153 ? 108.416 113.375 94.699  1.00 2.03  ? 132  GLY A C   1 
ATOM   954   O O   . GLY A 1 153 ? 109.293 113.752 95.481  1.00 2.03  ? 132  GLY A O   1 
ATOM   955   N N   . VAL A 1 154 ? 107.774 112.214 94.842  1.00 3.17  ? 133  VAL A N   1 
ATOM   956   C CA  . VAL A 1 154 ? 108.058 111.344 95.977  1.00 3.17  ? 133  VAL A CA  1 
ATOM   957   C C   . VAL A 1 154 ? 109.483 110.817 95.938  1.00 3.17  ? 133  VAL A C   1 
ATOM   958   O O   . VAL A 1 154 ? 109.996 110.360 96.962  1.00 3.17  ? 133  VAL A O   1 
ATOM   959   C CB  . VAL A 1 154 ? 107.049 110.180 96.053  1.00 3.17  ? 133  VAL A CB  1 
ATOM   960   C CG1 . VAL A 1 154 ? 105.645 110.697 95.955  1.00 3.17  ? 133  VAL A CG1 1 
ATOM   961   C CG2 . VAL A 1 154 ? 107.312 109.175 94.967  1.00 3.17  ? 133  VAL A CG2 1 
ATOM   962   N N   . LEU A 1 155 ? 110.136 110.852 94.775  1.00 1.58  ? 134  LEU A N   1 
ATOM   963   C CA  . LEU A 1 155 ? 111.564 110.574 94.732  1.00 1.58  ? 134  LEU A CA  1 
ATOM   964   C C   . LEU A 1 155 ? 112.363 111.711 95.348  1.00 1.58  ? 134  LEU A C   1 
ATOM   965   O O   . LEU A 1 155 ? 113.303 111.471 96.114  1.00 1.58  ? 134  LEU A O   1 
ATOM   966   C CB  . LEU A 1 155 ? 112.004 110.332 93.295  1.00 1.58  ? 134  LEU A CB  1 
ATOM   967   C CG  . LEU A 1 155 ? 113.509 110.247 93.108  1.00 1.58  ? 134  LEU A CG  1 
ATOM   968   C CD1 . LEU A 1 155 ? 114.044 109.031 93.829  1.00 1.58  ? 134  LEU A CD1 1 
ATOM   969   C CD2 . LEU A 1 155 ? 113.850 110.203 91.639  1.00 1.58  ? 134  LEU A CD2 1 
ATOM   970   N N   . ARG A 1 156 ? 112.014 112.958 95.021  1.00 2.07  ? 135  ARG A N   1 
ATOM   971   C CA  . ARG A 1 156 ? 112.704 114.084 95.650  1.00 2.07  ? 135  ARG A CA  1 
ATOM   972   C C   . ARG A 1 156 ? 112.482 114.119 97.153  1.00 2.07  ? 135  ARG A C   1 
ATOM   973   O O   . ARG A 1 156 ? 113.373 114.535 97.897  1.00 2.07  ? 135  ARG A O   1 
ATOM   974   C CB  . ARG A 1 156 ? 112.261 115.411 95.043  1.00 2.07  ? 135  ARG A CB  1 
ATOM   975   C CG  . ARG A 1 156 ? 112.696 115.599 93.623  1.00 2.07  ? 135  ARG A CG  1 
ATOM   976   C CD  . ARG A 1 156 ? 114.199 115.580 93.517  1.00 2.07  ? 135  ARG A CD  1 
ATOM   977   N NE  . ARG A 1 156 ? 114.845 116.477 94.467  1.00 2.07  ? 135  ARG A NE  1 
ATOM   978   C CZ  . ARG A 1 156 ? 115.269 117.701 94.172  1.00 2.07  ? 135  ARG A CZ  1 
ATOM   979   N NH1 . ARG A 1 156 ? 115.117 118.185 92.949  1.00 2.07  ? 135  ARG A NH1 1 
ATOM   980   N NH2 . ARG A 1 156 ? 115.846 118.442 95.104  1.00 2.07  ? 135  ARG A NH2 1 
ATOM   981   N N   . ALA A 1 157 ? 111.315 113.696 97.618  1.00 1.77  ? 136  ALA A N   1 
ATOM   982   C CA  . ALA A 1 157 ? 110.984 113.775 99.032  1.00 1.77  ? 136  ALA A CA  1 
ATOM   983   C C   . ALA A 1 157 ? 111.358 112.522 99.809  1.00 1.77  ? 136  ALA A C   1 
ATOM   984   O O   . ALA A 1 157 ? 111.103 112.462 101.015 1.00 1.77  ? 136  ALA A O   1 
ATOM   985   C CB  . ALA A 1 157 ? 109.493 114.057 99.204  1.00 1.77  ? 136  ALA A CB  1 
ATOM   986   N N   . GLN A 1 158 ? 111.956 111.529 99.159  1.00 1.47  ? 137  GLN A N   1 
ATOM   987   C CA  . GLN A 1 158 ? 112.266 110.258 99.800  1.00 1.47  ? 137  GLN A CA  1 
ATOM   988   C C   . GLN A 1 158 ? 113.584 110.368 100.546 1.00 1.47  ? 137  GLN A C   1 
ATOM   989   O O   . GLN A 1 158 ? 114.595 110.788 99.976  1.00 1.47  ? 137  GLN A O   1 
ATOM   990   C CB  . GLN A 1 158 ? 112.346 109.127 98.778  1.00 1.47  ? 137  GLN A CB  1 
ATOM   991   C CG  . GLN A 1 158 ? 112.809 107.814 99.371  1.00 1.47  ? 137  GLN A CG  1 
ATOM   992   C CD  . GLN A 1 158 ? 113.064 106.759 98.328  1.00 1.47  ? 137  GLN A CD  1 
ATOM   993   O OE1 . GLN A 1 158 ? 112.525 105.658 98.400  1.00 1.47  ? 137  GLN A OE1 1 
ATOM   994   N NE2 . GLN A 1 158 ? 113.902 107.080 97.358  1.00 1.47  ? 137  GLN A NE2 1 
ATOM   995   N N   . GLU A 1 159 ? 113.576 109.976 101.810 1.00 1.84  ? 138  GLU A N   1 
ATOM   996   C CA  . GLU A 1 159 ? 114.769 109.954 102.636 1.00 1.84  ? 138  GLU A CA  1 
ATOM   997   C C   . GLU A 1 159 ? 114.873 108.616 103.348 1.00 1.84  ? 138  GLU A C   1 
ATOM   998   O O   . GLU A 1 159 ? 113.859 108.014 103.706 1.00 1.84  ? 138  GLU A O   1 
ATOM   999   C CB  . GLU A 1 159 ? 114.741 111.104 103.636 1.00 1.84  ? 138  GLU A CB  1 
ATOM   1000  C CG  . GLU A 1 159 ? 113.711 110.947 104.718 1.00 1.84  ? 138  GLU A CG  1 
ATOM   1001  C CD  . GLU A 1 159 ? 113.350 112.268 105.337 1.00 1.84  ? 138  GLU A CD  1 
ATOM   1002  O OE1 . GLU A 1 159 ? 114.198 113.182 105.306 1.00 1.84  ? 138  GLU A OE1 1 
ATOM   1003  O OE2 . GLU A 1 159 ? 112.216 112.396 105.840 1.00 1.84  ? 138  GLU A OE2 1 
ATOM   1004  N N   . GLY A 1 160 ? 116.099 108.146 103.538 1.00 1.53  ? 139  GLY A N   1 
ATOM   1005  C CA  . GLY A 1 160 ? 116.300 106.881 104.209 1.00 1.53  ? 139  GLY A CA  1 
ATOM   1006  C C   . GLY A 1 160 ? 116.117 107.005 105.705 1.00 1.53  ? 139  GLY A C   1 
ATOM   1007  O O   . GLY A 1 160 ? 115.258 107.763 106.163 1.00 1.53  ? 139  GLY A O   1 
ATOM   1008  N N   . SER A 1 161 ? 116.906 106.276 106.487 1.00 1.76  ? 140  SER A N   1 
ATOM   1009  C CA  . SER A 1 161 ? 116.662 106.258 107.916 1.00 1.76  ? 140  SER A CA  1 
ATOM   1010  C C   . SER A 1 161 ? 117.961 106.076 108.686 1.00 1.76  ? 140  SER A C   1 
ATOM   1011  O O   . SER A 1 161 ? 118.922 105.490 108.187 1.00 1.76  ? 140  SER A O   1 
ATOM   1012  C CB  . SER A 1 161 ? 115.670 105.154 108.271 1.00 1.76  ? 140  SER A CB  1 
ATOM   1013  O OG  . SER A 1 161 ? 114.413 105.425 107.702 1.00 1.76  ? 140  SER A OG  1 
ATOM   1014  N N   . ILE A 1 162 ? 117.965 106.585 109.915 1.00 1.69  ? 141  ILE A N   1 
ATOM   1015  C CA  . ILE A 1 162 ? 119.070 106.468 110.856 1.00 1.69  ? 141  ILE A CA  1 
ATOM   1016  C C   . ILE A 1 162 ? 118.491 105.900 112.140 1.00 1.69  ? 141  ILE A C   1 
ATOM   1017  O O   . ILE A 1 162 ? 117.294 106.026 112.401 1.00 1.69  ? 141  ILE A O   1 
ATOM   1018  C CB  . ILE A 1 162 ? 119.761 107.838 111.101 1.00 1.69  ? 141  ILE A CB  1 
ATOM   1019  C CG1 . ILE A 1 162 ? 120.757 108.154 109.995 1.00 1.69  ? 141  ILE A CG1 1 
ATOM   1020  C CG2 . ILE A 1 162 ? 120.478 107.907 112.433 1.00 1.69  ? 141  ILE A CG2 1 
ATOM   1021  C CD1 . ILE A 1 162 ? 121.386 109.494 110.149 1.00 1.69  ? 141  ILE A CD1 1 
ATOM   1022  N N   . SER A 1 163 ? 119.323 105.224 112.923 1.00 2.98  ? 142  SER A N   1 
ATOM   1023  C CA  . SER A 1 163 ? 118.910 104.751 114.237 1.00 2.98  ? 142  SER A CA  1 
ATOM   1024  C C   . SER A 1 163 ? 120.085 104.873 115.187 1.00 2.98  ? 142  SER A C   1 
ATOM   1025  O O   . SER A 1 163 ? 121.097 104.187 115.014 1.00 2.98  ? 142  SER A O   1 
ATOM   1026  C CB  . SER A 1 163 ? 118.425 103.307 114.180 1.00 2.98  ? 142  SER A CB  1 
ATOM   1027  O OG  . SER A 1 163 ? 119.511 102.424 114.033 1.00 2.98  ? 142  SER A OG  1 
ATOM   1028  N N   . GLN A 1 164 ? 119.955 105.752 116.174 1.00 4.29  ? 143  GLN A N   1 
ATOM   1029  C CA  . GLN A 1 164 ? 120.957 105.886 117.224 1.00 4.29  ? 143  GLN A CA  1 
ATOM   1030  C C   . GLN A 1 164 ? 120.805 104.711 118.172 1.00 4.29  ? 143  GLN A C   1 
ATOM   1031  O O   . GLN A 1 164 ? 119.965 104.728 119.073 1.00 4.29  ? 143  GLN A O   1 
ATOM   1032  C CB  . GLN A 1 164 ? 120.792 107.210 117.960 1.00 4.29  ? 143  GLN A CB  1 
ATOM   1033  C CG  . GLN A 1 164 ? 122.034 107.674 118.707 1.00 4.29  ? 143  GLN A CG  1 
ATOM   1034  C CD  . GLN A 1 164 ? 123.205 107.936 117.783 1.00 4.29  ? 143  GLN A CD  1 
ATOM   1035  O OE1 . GLN A 1 164 ? 123.024 108.238 116.605 1.00 4.29  ? 143  GLN A OE1 1 
ATOM   1036  N NE2 . GLN A 1 164 ? 124.414 107.825 118.315 1.00 4.29  ? 143  GLN A NE2 1 
ATOM   1037  N N   . ILE A 1 165 ? 121.606 103.670 117.962 1.00 5.58  ? 144  ILE A N   1 
ATOM   1038  C CA  . ILE A 1 165 ? 121.530 102.500 118.825 1.00 5.58  ? 144  ILE A CA  1 
ATOM   1039  C C   . ILE A 1 165 ? 121.999 102.853 120.227 1.00 5.58  ? 144  ILE A C   1 
ATOM   1040  O O   . ILE A 1 165 ? 121.319 102.574 121.220 1.00 5.58  ? 144  ILE A O   1 
ATOM   1041  C CB  . ILE A 1 165 ? 122.350 101.345 118.227 1.00 5.58  ? 144  ILE A CB  1 
ATOM   1042  C CG1 . ILE A 1 165 ? 121.868 101.060 116.805 1.00 5.58  ? 144  ILE A CG1 1 
ATOM   1043  C CG2 . ILE A 1 165 ? 122.276 100.119 119.112 1.00 5.58  ? 144  ILE A CG2 1 
ATOM   1044  C CD1 . ILE A 1 165 ? 120.400 100.757 116.714 1.00 5.58  ? 144  ILE A CD1 1 
ATOM   1045  N N   . ASP A 1 166 ? 123.160 103.486 120.325 1.00 6.78  ? 145  ASP A N   1 
ATOM   1046  C CA  . ASP A 1 166 ? 123.680 104.003 121.580 1.00 6.78  ? 145  ASP A CA  1 
ATOM   1047  C C   . ASP A 1 166 ? 124.539 105.217 121.242 1.00 6.78  ? 145  ASP A C   1 
ATOM   1048  O O   . ASP A 1 166 ? 124.446 105.767 120.141 1.00 6.78  ? 145  ASP A O   1 
ATOM   1049  C CB  . ASP A 1 166 ? 124.431 102.903 122.351 1.00 6.78  ? 145  ASP A CB  1 
ATOM   1050  C CG  . ASP A 1 166 ? 125.567 102.303 121.557 1.00 6.78  ? 145  ASP A CG  1 
ATOM   1051  O OD1 . ASP A 1 166 ? 125.799 102.756 120.422 1.00 6.78  ? 145  ASP A OD1 1 
ATOM   1052  O OD2 . ASP A 1 166 ? 126.229 101.377 122.069 1.00 6.78  ? 145  ASP A OD2 1 
ATOM   1053  N N   . ASP A 1 167 ? 125.372 105.644 122.188 1.00 6.56  ? 146  ASP A N   1 
ATOM   1054  C CA  . ASP A 1 167 ? 126.231 106.790 121.924 1.00 6.56  ? 146  ASP A CA  1 
ATOM   1055  C C   . ASP A 1 167 ? 127.291 106.473 120.877 1.00 6.56  ? 146  ASP A C   1 
ATOM   1056  O O   . ASP A 1 167 ? 127.760 107.378 120.180 1.00 6.56  ? 146  ASP A O   1 
ATOM   1057  C CB  . ASP A 1 167 ? 126.886 107.262 123.221 1.00 6.56  ? 146  ASP A CB  1 
ATOM   1058  C CG  . ASP A 1 167 ? 127.909 108.357 122.995 1.00 6.56  ? 146  ASP A CG  1 
ATOM   1059  O OD1 . ASP A 1 167 ? 127.517 109.542 122.946 1.00 6.56  ? 146  ASP A OD1 1 
ATOM   1060  O OD2 . ASP A 1 167 ? 129.107 108.032 122.870 1.00 6.56  ? 146  ASP A OD2 1 
ATOM   1061  N N   . ASP A 1 168 ? 127.665 105.204 120.735 1.00 6.04  ? 147  ASP A N   1 
ATOM   1062  C CA  . ASP A 1 168 ? 128.811 104.831 119.923 1.00 6.04  ? 147  ASP A CA  1 
ATOM   1063  C C   . ASP A 1 168 ? 128.462 104.037 118.673 1.00 6.04  ? 147  ASP A C   1 
ATOM   1064  O O   . ASP A 1 168 ? 129.348 103.812 117.844 1.00 6.04  ? 147  ASP A O   1 
ATOM   1065  C CB  . ASP A 1 168 ? 129.804 104.019 120.764 1.00 6.04  ? 147  ASP A CB  1 
ATOM   1066  C CG  . ASP A 1 168 ? 130.185 104.717 122.055 1.00 6.04  ? 147  ASP A CG  1 
ATOM   1067  O OD1 . ASP A 1 168 ? 129.405 104.641 123.027 1.00 6.04  ? 147  ASP A OD1 1 
ATOM   1068  O OD2 . ASP A 1 168 ? 131.264 105.340 122.100 1.00 6.04  ? 147  ASP A OD2 1 
ATOM   1069  N N   . THR A 1 169 ? 127.216 103.605 118.511 1.00 4.38  ? 148  THR A N   1 
ATOM   1070  C CA  . THR A 1 169 ? 126.822 102.783 117.375 1.00 4.38  ? 148  THR A CA  1 
ATOM   1071  C C   . THR A 1 169 ? 125.594 103.393 116.721 1.00 4.38  ? 148  THR A C   1 
ATOM   1072  O O   . THR A 1 169 ? 124.616 103.708 117.403 1.00 4.38  ? 148  THR A O   1 
ATOM   1073  C CB  . THR A 1 169 ? 126.539 101.338 117.807 1.00 4.38  ? 148  THR A CB  1 
ATOM   1074  O OG1 . THR A 1 169 ? 127.621 100.860 118.612 1.00 4.38  ? 148  THR A OG1 1 
ATOM   1075  C CG2 . THR A 1 169 ? 126.395 100.434 116.607 1.00 4.38  ? 148  THR A CG2 1 
ATOM   1076  N N   . VAL A 1 170 ? 125.652 103.563 115.404 1.00 2.87  ? 149  VAL A N   1 
ATOM   1077  C CA  . VAL A 1 170 ? 124.549 104.099 114.618 1.00 2.87  ? 149  VAL A CA  1 
ATOM   1078  C C   . VAL A 1 170 ? 124.267 103.137 113.476 1.00 2.87  ? 149  VAL A C   1 
ATOM   1079  O O   . VAL A 1 170 ? 125.195 102.596 112.873 1.00 2.87  ? 149  VAL A O   1 
ATOM   1080  C CB  . VAL A 1 170 ? 124.863 105.506 114.063 1.00 2.87  ? 149  VAL A CB  1 
ATOM   1081  C CG1 . VAL A 1 170 ? 123.611 106.163 113.543 1.00 2.87  ? 149  VAL A CG1 1 
ATOM   1082  C CG2 . VAL A 1 170 ? 125.501 106.374 115.118 1.00 2.87  ? 149  VAL A CG2 1 
ATOM   1083  N N   . ALA A 1 171 ? 122.994 102.933 113.163 1.00 2.31  ? 150  ALA A N   1 
ATOM   1084  C CA  . ALA A 1 171 ? 122.611 102.150 111.997 1.00 2.31  ? 150  ALA A CA  1 
ATOM   1085  C C   . ALA A 1 171 ? 122.065 103.079 110.927 1.00 2.31  ? 150  ALA A C   1 
ATOM   1086  O O   . ALA A 1 171 ? 121.184 103.895 111.197 1.00 2.31  ? 150  ALA A O   1 
ATOM   1087  C CB  . ALA A 1 171 ? 121.579 101.081 112.348 1.00 2.31  ? 150  ALA A CB  1 
ATOM   1088  N N   . TYR A 1 172 ? 122.594 102.953 109.721 1.00 1.91  ? 151  TYR A N   1 
ATOM   1089  C CA  . TYR A 1 172 ? 122.237 103.795 108.592 1.00 1.91  ? 151  TYR A CA  1 
ATOM   1090  C C   . TYR A 1 172 ? 121.458 102.961 107.590 1.00 1.91  ? 151  TYR A C   1 
ATOM   1091  O O   . TYR A 1 172 ? 121.986 101.986 107.053 1.00 1.91  ? 151  TYR A O   1 
ATOM   1092  C CB  . TYR A 1 172 ? 123.491 104.369 107.942 1.00 1.91  ? 151  TYR A CB  1 
ATOM   1093  C CG  . TYR A 1 172 ? 124.288 105.275 108.835 1.00 1.91  ? 151  TYR A CG  1 
ATOM   1094  C CD1 . TYR A 1 172 ? 123.733 106.428 109.354 1.00 1.91  ? 151  TYR A CD1 1 
ATOM   1095  C CD2 . TYR A 1 172 ? 125.599 104.983 109.156 1.00 1.91  ? 151  TYR A CD2 1 
ATOM   1096  C CE1 . TYR A 1 172 ? 124.455 107.255 110.165 1.00 1.91  ? 151  TYR A CE1 1 
ATOM   1097  C CE2 . TYR A 1 172 ? 126.327 105.808 109.969 1.00 1.91  ? 151  TYR A CE2 1 
ATOM   1098  C CZ  . TYR A 1 172 ? 125.751 106.942 110.466 1.00 1.91  ? 151  TYR A CZ  1 
ATOM   1099  O OH  . TYR A 1 172 ? 126.480 107.772 111.277 1.00 1.91  ? 151  TYR A OH  1 
ATOM   1100  N N   . HIS A 1 173 ? 120.219 103.347 107.328 1.00 2.30  ? 152  HIS A N   1 
ATOM   1101  C CA  . HIS A 1 173 ? 119.354 102.618 106.408 1.00 2.30  ? 152  HIS A CA  1 
ATOM   1102  C C   . HIS A 1 173 ? 119.268 103.403 105.108 1.00 2.30  ? 152  HIS A C   1 
ATOM   1103  O O   . HIS A 1 173 ? 118.556 104.402 105.014 1.00 2.30  ? 152  HIS A O   1 
ATOM   1104  C CB  . HIS A 1 173 ? 117.983 102.392 107.028 1.00 2.30  ? 152  HIS A CB  1 
ATOM   1105  C CG  . HIS A 1 173 ? 118.028 101.629 108.312 1.00 2.30  ? 152  HIS A CG  1 
ATOM   1106  N ND1 . HIS A 1 173 ? 117.855 102.226 109.540 1.00 2.30  ? 152  HIS A ND1 1 
ATOM   1107  C CD2 . HIS A 1 173 ? 118.242 100.317 108.559 1.00 2.30  ? 152  HIS A CD2 1 
ATOM   1108  C CE1 . HIS A 1 173 ? 117.952 101.314 110.489 1.00 2.30  ? 152  HIS A CE1 1 
ATOM   1109  N NE2 . HIS A 1 173 ? 118.191 100.148 109.920 1.00 2.30  ? 152  HIS A NE2 1 
ATOM   1110  N N   . PHE A 1 174 ? 119.991 102.938 104.104 1.00 2.22  ? 153  PHE A N   1 
ATOM   1111  C CA  . PHE A 1 174 ? 120.015 103.563 102.795 1.00 2.22  ? 153  PHE A CA  1 
ATOM   1112  C C   . PHE A 1 174 ? 118.977 102.908 101.900 1.00 2.22  ? 153  PHE A C   1 
ATOM   1113  O O   . PHE A 1 174 ? 118.771 101.694 101.965 1.00 2.22  ? 153  PHE A O   1 
ATOM   1114  C CB  . PHE A 1 174 ? 121.397 103.433 102.163 1.00 2.22  ? 153  PHE A CB  1 
ATOM   1115  C CG  . PHE A 1 174 ? 122.458 104.220 102.858 1.00 2.22  ? 153  PHE A CG  1 
ATOM   1116  C CD1 . PHE A 1 174 ? 122.687 105.540 102.527 1.00 2.22  ? 153  PHE A CD1 1 
ATOM   1117  C CD2 . PHE A 1 174 ? 123.236 103.639 103.839 1.00 2.22  ? 153  PHE A CD2 1 
ATOM   1118  C CE1 . PHE A 1 174 ? 123.666 106.264 103.166 1.00 2.22  ? 153  PHE A CE1 1 
ATOM   1119  C CE2 . PHE A 1 174 ? 124.216 104.360 104.482 1.00 2.22  ? 153  PHE A CE2 1 
ATOM   1120  C CZ  . PHE A 1 174 ? 124.432 105.673 104.145 1.00 2.22  ? 153  PHE A CZ  1 
ATOM   1121  N N   . HIS A 1 175 ? 118.319 103.713 101.077 1.00 1.44  ? 154  HIS A N   1 
ATOM   1122  C CA  . HIS A 1 175 ? 117.512 103.173 99.997  1.00 1.44  ? 154  HIS A CA  1 
ATOM   1123  C C   . HIS A 1 175 ? 118.402 102.892 98.800  1.00 1.44  ? 154  HIS A C   1 
ATOM   1124  O O   . HIS A 1 175 ? 119.208 103.736 98.405  1.00 1.44  ? 154  HIS A O   1 
ATOM   1125  C CB  . HIS A 1 175 ? 116.413 104.153 99.615  1.00 1.44  ? 154  HIS A CB  1 
ATOM   1126  C CG  . HIS A 1 175 ? 115.347 104.300 100.650 1.00 1.44  ? 154  HIS A CG  1 
ATOM   1127  N ND1 . HIS A 1 175 ? 114.704 103.221 101.211 1.00 1.44  ? 154  HIS A ND1 1 
ATOM   1128  C CD2 . HIS A 1 175 ? 114.799 105.400 101.213 1.00 1.44  ? 154  HIS A CD2 1 
ATOM   1129  C CE1 . HIS A 1 175 ? 113.809 103.650 102.081 1.00 1.44  ? 154  HIS A CE1 1 
ATOM   1130  N NE2 . HIS A 1 175 ? 113.848 104.968 102.102 1.00 1.44  ? 154  HIS A NE2 1 
ATOM   1131  N N   . GLU A 1 176 ? 118.264 101.710 98.222  1.00 2.14  ? 155  GLU A N   1 
ATOM   1132  C CA  . GLU A 1 176 ? 119.071 101.346 97.075  1.00 2.14  ? 155  GLU A CA  1 
ATOM   1133  C C   . GLU A 1 176 ? 118.176 100.801 95.978  1.00 2.14  ? 155  GLU A C   1 
ATOM   1134  O O   . GLU A 1 176 ? 117.115 100.237 96.260  1.00 2.14  ? 155  GLU A O   1 
ATOM   1135  C CB  . GLU A 1 176 ? 120.131 100.298 97.432  1.00 2.14  ? 155  GLU A CB  1 
ATOM   1136  C CG  . GLU A 1 176 ? 121.416 100.882 97.950  1.00 2.14  ? 155  GLU A CG  1 
ATOM   1137  C CD  . GLU A 1 176 ? 122.553 99.893  97.901  1.00 2.14  ? 155  GLU A CD  1 
ATOM   1138  O OE1 . GLU A 1 176 ? 122.281 98.690  97.726  1.00 2.14  ? 155  GLU A OE1 1 
ATOM   1139  O OE2 . GLU A 1 176 ? 123.720 100.319 98.024  1.00 2.14  ? 155  GLU A OE2 1 
ATOM   1140  N N   . PRO A 1 177 ? 118.573 100.965 94.722  1.00 1.97  ? 156  PRO A N   1 
ATOM   1141  C CA  . PRO A 1 177 ? 117.873 100.275 93.640  1.00 1.97  ? 156  PRO A CA  1 
ATOM   1142  C C   . PRO A 1 177 ? 117.984 98.769  93.799  1.00 1.97  ? 156  PRO A C   1 
ATOM   1143  O O   . PRO A 1 177 ? 118.952 98.251  94.357  1.00 1.97  ? 156  PRO A O   1 
ATOM   1144  C CB  . PRO A 1 177 ? 118.603 100.757 92.384  1.00 1.97  ? 156  PRO A CB  1 
ATOM   1145  C CG  . PRO A 1 177 ? 119.196 102.048 92.771  1.00 1.97  ? 156  PRO A CG  1 
ATOM   1146  C CD  . PRO A 1 177 ? 119.547 101.942 94.216  1.00 1.97  ? 156  PRO A CD  1 
ATOM   1147  N N   . LEU A 1 178 ? 116.965 98.066  93.314  1.00 1.88  ? 157  LEU A N   1 
ATOM   1148  C CA  . LEU A 1 178 ? 117.037 96.617  93.218  1.00 1.88  ? 157  LEU A CA  1 
ATOM   1149  C C   . LEU A 1 178 ? 117.945 96.166  92.093  1.00 1.88  ? 157  LEU A C   1 
ATOM   1150  O O   . LEU A 1 178 ? 118.403 95.020  92.104  1.00 1.88  ? 157  LEU A O   1 
ATOM   1151  C CB  . LEU A 1 178 ? 115.647 96.027  93.003  1.00 1.88  ? 157  LEU A CB  1 
ATOM   1152  C CG  . LEU A 1 178 ? 114.659 96.139  94.158  1.00 1.88  ? 157  LEU A CG  1 
ATOM   1153  C CD1 . LEU A 1 178 ? 113.292 95.711  93.694  1.00 1.88  ? 157  LEU A CD1 1 
ATOM   1154  C CD2 . LEU A 1 178 ? 115.104 95.302  95.329  1.00 1.88  ? 157  LEU A CD2 1 
ATOM   1155  N N   . GLY A 1 179 ? 118.226 97.040  91.138  1.00 2.31  ? 158  GLY A N   1 
ATOM   1156  C CA  . GLY A 1 179 ? 118.990 96.659  89.971  1.00 2.31  ? 158  GLY A CA  1 
ATOM   1157  C C   . GLY A 1 179 ? 118.130 96.682  88.731  1.00 2.31  ? 158  GLY A C   1 
ATOM   1158  O O   . GLY A 1 179 ? 117.759 97.754  88.252  1.00 2.31  ? 158  GLY A O   1 
ATOM   1159  N N   . VAL A 1 180 ? 117.798 95.507  88.208  1.00 2.86  ? 159  VAL A N   1 
ATOM   1160  C CA  . VAL A 1 180 ? 116.948 95.368  87.034  1.00 2.86  ? 159  VAL A CA  1 
ATOM   1161  C C   . VAL A 1 180 ? 115.666 94.670  87.451  1.00 2.86  ? 159  VAL A C   1 
ATOM   1162  O O   . VAL A 1 180 ? 115.707 93.629  88.115  1.00 2.86  ? 159  VAL A O   1 
ATOM   1163  C CB  . VAL A 1 180 ? 117.657 94.591  85.917  1.00 2.86  ? 159  VAL A CB  1 
ATOM   1164  C CG1 . VAL A 1 180 ? 116.736 94.429  84.729  1.00 2.86  ? 159  VAL A CG1 1 
ATOM   1165  C CG2 . VAL A 1 180 ? 118.920 95.309  85.516  1.00 2.86  ? 159  VAL A CG2 1 
ATOM   1166  N N   . VAL A 1 181 ? 114.530 95.242  87.069  1.00 2.18  ? 160  VAL A N   1 
ATOM   1167  C CA  . VAL A 1 181 ? 113.226 94.666  87.354  1.00 2.18  ? 160  VAL A CA  1 
ATOM   1168  C C   . VAL A 1 181 ? 112.535 94.372  86.034  1.00 2.18  ? 160  VAL A C   1 
ATOM   1169  O O   . VAL A 1 181 ? 112.827 95.006  85.017  1.00 2.18  ? 160  VAL A O   1 
ATOM   1170  C CB  . VAL A 1 181 ? 112.366 95.597  88.228  1.00 2.18  ? 160  VAL A CB  1 
ATOM   1171  C CG1 . VAL A 1 181 ? 113.092 95.924  89.511  1.00 2.18  ? 160  VAL A CG1 1 
ATOM   1172  C CG2 . VAL A 1 181 ? 112.022 96.857  87.475  1.00 2.18  ? 160  VAL A CG2 1 
ATOM   1173  N N   . GLY A 1 182 ? 111.646 93.391  86.044  1.00 3.64  ? 161  GLY A N   1 
ATOM   1174  C CA  . GLY A 1 182 ? 110.858 93.032  84.876  1.00 3.64  ? 161  GLY A CA  1 
ATOM   1175  C C   . GLY A 1 182 ? 109.383 93.206  85.187  1.00 3.64  ? 161  GLY A C   1 
ATOM   1176  O O   . GLY A 1 182 ? 108.939 92.925  86.302  1.00 3.64  ? 161  GLY A O   1 
ATOM   1177  N N   . GLN A 1 183 ? 108.630 93.680  84.203  1.00 4.02  ? 162  GLN A N   1 
ATOM   1178  C CA  . GLN A 1 183 ? 107.208 93.911  84.394  1.00 4.02  ? 162  GLN A CA  1 
ATOM   1179  C C   . GLN A 1 183 ? 106.440 93.408  83.187  1.00 4.02  ? 162  GLN A C   1 
ATOM   1180  O O   . GLN A 1 183 ? 106.843 93.633  82.044  1.00 4.02  ? 162  GLN A O   1 
ATOM   1181  C CB  . GLN A 1 183 ? 106.907 95.393  84.629  1.00 4.02  ? 162  GLN A CB  1 
ATOM   1182  C CG  . GLN A 1 183 ? 107.591 95.965  85.850  1.00 4.02  ? 162  GLN A CG  1 
ATOM   1183  C CD  . GLN A 1 183 ? 107.818 97.446  85.744  1.00 4.02  ? 162  GLN A CD  1 
ATOM   1184  O OE1 . GLN A 1 183 ? 107.990 97.977  84.653  1.00 4.02  ? 162  GLN A OE1 1 
ATOM   1185  N NE2 . GLN A 1 183 ? 107.825 98.128  86.879  1.00 4.02  ? 162  GLN A NE2 1 
ATOM   1186  N N   . ILE A 1 184 ? 105.334 92.726  83.455  1.00 5.85  ? 163  ILE A N   1 
ATOM   1187  C CA  . ILE A 1 184 ? 104.424 92.234  82.433  1.00 5.85  ? 163  ILE A CA  1 
ATOM   1188  C C   . ILE A 1 184 ? 103.131 93.014  82.597  1.00 5.85  ? 163  ILE A C   1 
ATOM   1189  O O   . ILE A 1 184 ? 102.434 92.865  83.606  1.00 5.85  ? 163  ILE A O   1 
ATOM   1190  C CB  . ILE A 1 184 ? 104.192 90.724  82.563  1.00 5.85  ? 163  ILE A CB  1 
ATOM   1191  C CG1 . ILE A 1 184 ? 105.445 89.960  82.138  1.00 5.85  ? 163  ILE A CG1 1 
ATOM   1192  C CG2 . ILE A 1 184 ? 103.001 90.292  81.734  1.00 5.85  ? 163  ILE A CG2 1 
ATOM   1193  C CD1 . ILE A 1 184 ? 105.499 88.551  82.655  1.00 5.85  ? 163  ILE A CD1 1 
ATOM   1194  N N   . ILE A 1 185 ? 102.811 93.855  81.620  1.00 5.92  ? 164  ILE A N   1 
ATOM   1195  C CA  . ILE A 1 185 ? 101.666 94.752  81.748  1.00 5.92  ? 164  ILE A CA  1 
ATOM   1196  C C   . ILE A 1 185 ? 100.460 94.139  81.050  1.00 5.92  ? 164  ILE A C   1 
ATOM   1197  O O   . ILE A 1 185 ? 100.613 93.477  80.015  1.00 5.92  ? 164  ILE A O   1 
ATOM   1198  C CB  . ILE A 1 185 ? 101.977 96.147  81.184  1.00 5.92  ? 164  ILE A CB  1 
ATOM   1199  C CG1 . ILE A 1 185 ? 102.581 96.037  79.791  1.00 5.92  ? 164  ILE A CG1 1 
ATOM   1200  C CG2 . ILE A 1 185 ? 102.913 96.900  82.112  1.00 5.92  ? 164  ILE A CG2 1 
ATOM   1201  C CD1 . ILE A 1 185 ? 102.701 97.356  79.081  1.00 5.92  ? 164  ILE A CD1 1 
ATOM   1202  N N   . PRO A 1 186 ? 99.253  94.334  81.570  1.00 7.72  ? 165  PRO A N   1 
ATOM   1203  C CA  . PRO A 1 186 ? 98.067  93.796  80.899  1.00 7.72  ? 165  PRO A CA  1 
ATOM   1204  C C   . PRO A 1 186 ? 97.719  94.599  79.659  1.00 7.72  ? 165  PRO A C   1 
ATOM   1205  O O   . PRO A 1 186 ? 98.470  95.497  79.269  1.00 7.72  ? 165  PRO A O   1 
ATOM   1206  C CB  . PRO A 1 186 ? 96.982  93.912  81.974  1.00 7.72  ? 165  PRO A CB  1 
ATOM   1207  C CG  . PRO A 1 186 ? 97.402  95.090  82.776  1.00 7.72  ? 165  PRO A CG  1 
ATOM   1208  C CD  . PRO A 1 186 ? 98.907  95.068  82.798  1.00 7.72  ? 165  PRO A CD  1 
ATOM   1209  N N   . TRP A 1 187 ? 96.594  94.288  79.022  1.00 7.98  ? 166  TRP A N   1 
ATOM   1210  C CA  . TRP A 1 187 ? 96.145  95.065  77.880  1.00 7.98  ? 166  TRP A CA  1 
ATOM   1211  C C   . TRP A 1 187 ? 94.928  95.930  78.167  1.00 7.98  ? 166  TRP A C   1 
ATOM   1212  O O   . TRP A 1 187 ? 94.583  96.766  77.327  1.00 7.98  ? 166  TRP A O   1 
ATOM   1213  C CB  . TRP A 1 187 ? 95.840  94.147  76.684  1.00 7.98  ? 166  TRP A CB  1 
ATOM   1214  C CG  . TRP A 1 187 ? 95.238  92.830  77.049  1.00 7.98  ? 166  TRP A CG  1 
ATOM   1215  C CD1 . TRP A 1 187 ? 95.876  91.631  77.106  1.00 7.98  ? 166  TRP A CD1 1 
ATOM   1216  C CD2 . TRP A 1 187 ? 93.876  92.578  77.404  1.00 7.98  ? 166  TRP A CD2 1 
ATOM   1217  N NE1 . TRP A 1 187 ? 94.998  90.645  77.479  1.00 7.98  ? 166  TRP A NE1 1 
ATOM   1218  C CE2 . TRP A 1 187 ? 93.762  91.203  77.670  1.00 7.98  ? 166  TRP A CE2 1 
ATOM   1219  C CE3 . TRP A 1 187 ? 92.742  93.383  77.528  1.00 7.98  ? 166  TRP A CE3 1 
ATOM   1220  C CZ2 . TRP A 1 187 ? 92.563  90.616  78.046  1.00 7.98  ? 166  TRP A CZ2 1 
ATOM   1221  C CZ3 . TRP A 1 187 ? 91.555  92.799  77.901  1.00 7.98  ? 166  TRP A CZ3 1 
ATOM   1222  C CH2 . TRP A 1 187 ? 91.472  91.430  78.157  1.00 7.98  ? 166  TRP A CH2 1 
ATOM   1223  N N   . ASN A 1 188 ? 94.267  95.764  79.315  1.00 7.76  ? 167  ASN A N   1 
ATOM   1224  C CA  . ASN A 1 188 ? 93.068  96.555  79.565  1.00 7.76  ? 167  ASN A CA  1 
ATOM   1225  C C   . ASN A 1 188 ? 93.397  98.040  79.664  1.00 7.76  ? 167  ASN A C   1 
ATOM   1226  O O   . ASN A 1 188 ? 92.656  98.883  79.147  1.00 7.76  ? 167  ASN A O   1 
ATOM   1227  C CB  . ASN A 1 188 ? 92.338  96.048  80.815  1.00 7.76  ? 167  ASN A CB  1 
ATOM   1228  C CG  . ASN A 1 188 ? 93.128  96.234  82.097  1.00 7.76  ? 167  ASN A CG  1 
ATOM   1229  O OD1 . ASN A 1 188 ? 93.646  97.309  82.381  1.00 7.76  ? 167  ASN A OD1 1 
ATOM   1230  N ND2 . ASN A 1 188 ? 93.194  95.182  82.898  1.00 7.76  ? 167  ASN A ND2 1 
ATOM   1231  N N   . PHE A 1 189 ? 94.508  98.377  80.317  1.00 5.20  ? 168  PHE A N   1 
ATOM   1232  C CA  . PHE A 1 189 ? 95.031  99.740  80.386  1.00 5.20  ? 168  PHE A CA  1 
ATOM   1233  C C   . PHE A 1 189 ? 96.482  99.677  79.933  1.00 5.20  ? 168  PHE A C   1 
ATOM   1234  O O   . PHE A 1 189 ? 97.390  99.575  80.768  1.00 5.20  ? 168  PHE A O   1 
ATOM   1235  C CB  . PHE A 1 189 ? 94.939  100.303 81.802  1.00 5.20  ? 168  PHE A CB  1 
ATOM   1236  C CG  . PHE A 1 189 ? 93.573  100.766 82.195  1.00 5.20  ? 168  PHE A CG  1 
ATOM   1237  C CD1 . PHE A 1 189 ? 92.981  101.832 81.557  1.00 5.20  ? 168  PHE A CD1 1 
ATOM   1238  C CD2 . PHE A 1 189 ? 92.891  100.152 83.228  1.00 5.20  ? 168  PHE A CD2 1 
ATOM   1239  C CE1 . PHE A 1 189 ? 91.725  102.267 81.928  1.00 5.20  ? 168  PHE A CE1 1 
ATOM   1240  C CE2 . PHE A 1 189 ? 91.641  100.581 83.603  1.00 5.20  ? 168  PHE A CE2 1 
ATOM   1241  C CZ  . PHE A 1 189 ? 91.057  101.643 82.954  1.00 5.20  ? 168  PHE A CZ  1 
ATOM   1242  N N   . PRO A 1 190 ? 96.753  99.713  78.636  1.00 6.44  ? 169  PRO A N   1 
ATOM   1243  C CA  . PRO A 1 190 ? 98.133  99.492  78.187  1.00 6.44  ? 169  PRO A CA  1 
ATOM   1244  C C   . PRO A 1 190 ? 99.086  100.574 78.665  1.00 6.44  ? 169  PRO A C   1 
ATOM   1245  O O   . PRO A 1 190 ? 100.025 100.296 79.418  1.00 6.44  ? 169  PRO A O   1 
ATOM   1246  C CB  . PRO A 1 190 ? 98.013  99.483  76.655  1.00 6.44  ? 169  PRO A CB  1 
ATOM   1247  C CG  . PRO A 1 190 ? 96.538  99.520  76.353  1.00 6.44  ? 169  PRO A CG  1 
ATOM   1248  C CD  . PRO A 1 190 ? 95.884  100.142 77.533  1.00 6.44  ? 169  PRO A CD  1 
ATOM   1249  N N   . LEU A 1 191 ? 98.818  101.824 78.292  1.00 4.50  ? 170  LEU A N   1 
ATOM   1250  C CA  . LEU A 1 191 ? 99.734  102.896 78.654  1.00 4.50  ? 170  LEU A CA  1 
ATOM   1251  C C   . LEU A 1 191 ? 99.577  103.304 80.108  1.00 4.50  ? 170  LEU A C   1 
ATOM   1252  O O   . LEU A 1 191 ? 100.566 103.663 80.751  1.00 4.50  ? 170  LEU A O   1 
ATOM   1253  C CB  . LEU A 1 191 ? 99.531  104.094 77.730  1.00 4.50  ? 170  LEU A CB  1 
ATOM   1254  C CG  . LEU A 1 191 ? 100.487 105.286 77.784  1.00 4.50  ? 170  LEU A CG  1 
ATOM   1255  C CD1 . LEU A 1 191 ? 100.503 105.966 76.435  1.00 4.50  ? 170  LEU A CD1 1 
ATOM   1256  C CD2 . LEU A 1 191 ? 100.085 106.289 78.851  1.00 4.50  ? 170  LEU A CD2 1 
ATOM   1257  N N   . LEU A 1 192 ? 98.360  103.247 80.648  1.00 4.17  ? 171  LEU A N   1 
ATOM   1258  C CA  . LEU A 1 192 ? 98.166  103.621 82.043  1.00 4.17  ? 171  LEU A CA  1 
ATOM   1259  C C   . LEU A 1 192 ? 98.900  102.668 82.977  1.00 4.17  ? 171  LEU A C   1 
ATOM   1260  O O   . LEU A 1 192 ? 99.583  103.105 83.905  1.00 4.17  ? 171  LEU A O   1 
ATOM   1261  C CB  . LEU A 1 192 ? 96.680  103.666 82.380  1.00 4.17  ? 171  LEU A CB  1 
ATOM   1262  C CG  . LEU A 1 192 ? 96.415  104.234 83.767  1.00 4.17  ? 171  LEU A CG  1 
ATOM   1263  C CD1 . LEU A 1 192 ? 97.213  105.498 83.950  1.00 4.17  ? 171  LEU A CD1 1 
ATOM   1264  C CD2 . LEU A 1 192 ? 94.945  104.501 83.969  1.00 4.17  ? 171  LEU A CD2 1 
ATOM   1265  N N   . MET A 1 193 ? 98.782  101.356 82.745  1.00 4.77  ? 172  MET A N   1 
ATOM   1266  C CA  . MET A 1 193 ? 99.530  100.411 83.571  1.00 4.77  ? 172  MET A CA  1 
ATOM   1267  C C   . MET A 1 193 ? 101.016 100.430 83.250  1.00 4.77  ? 172  MET A C   1 
ATOM   1268  O O   . MET A 1 193 ? 101.840 100.222 84.148  1.00 4.77  ? 172  MET A O   1 
ATOM   1269  C CB  . MET A 1 193 ? 98.982  98.994  83.424  1.00 4.77  ? 172  MET A CB  1 
ATOM   1270  C CG  . MET A 1 193 ? 97.532  98.851  83.805  1.00 4.77  ? 172  MET A CG  1 
ATOM   1271  S SD  . MET A 1 193 ? 97.176  99.714  85.344  1.00 4.77  ? 172  MET A SD  1 
ATOM   1272  C CE  . MET A 1 193 ? 95.420  99.429  85.493  1.00 4.77  ? 172  MET A CE  1 
ATOM   1273  N N   . ALA A 1 194 ? 101.384 100.702 81.997  1.00 3.43  ? 173  ALA A N   1 
ATOM   1274  C CA  . ALA A 1 194 ? 102.797 100.869 81.690  1.00 3.43  ? 173  ALA A CA  1 
ATOM   1275  C C   . ALA A 1 194 ? 103.400 101.990 82.520  1.00 3.43  ? 173  ALA A C   1 
ATOM   1276  O O   . ALA A 1 194 ? 104.480 101.834 83.094  1.00 3.43  ? 173  ALA A O   1 
ATOM   1277  C CB  . ALA A 1 194 ? 102.985 101.142 80.204  1.00 3.43  ? 173  ALA A CB  1 
ATOM   1278  N N   . CYS A 1 195 ? 102.694 103.114 82.632  1.00 2.60  ? 174  CYS A N   1 
ATOM   1279  C CA  . CYS A 1 195 ? 103.194 104.227 83.431  1.00 2.60  ? 174  CYS A CA  1 
ATOM   1280  C C   . CYS A 1 195 ? 103.124 103.921 84.919  1.00 2.60  ? 174  CYS A C   1 
ATOM   1281  O O   . CYS A 1 195 ? 104.052 104.252 85.663  1.00 2.60  ? 174  CYS A O   1 
ATOM   1282  C CB  . CYS A 1 195 ? 102.416 105.495 83.098  1.00 2.60  ? 174  CYS A CB  1 
ATOM   1283  S SG  . CYS A 1 195 ? 102.759 106.106 81.431  1.00 2.60  ? 174  CYS A SG  1 
ATOM   1284  N N   . TRP A 1 196 ? 102.042 103.280 85.370  1.00 3.61  ? 175  TRP A N   1 
ATOM   1285  C CA  . TRP A 1 196 ? 101.918 102.901 86.775  1.00 3.61  ? 175  TRP A CA  1 
ATOM   1286  C C   . TRP A 1 196 ? 103.074 102.027 87.228  1.00 3.61  ? 175  TRP A C   1 
ATOM   1287  O O   . TRP A 1 196 ? 103.501 102.115 88.383  1.00 3.61  ? 175  TRP A O   1 
ATOM   1288  C CB  . TRP A 1 196 ? 100.611 102.152 87.013  1.00 3.61  ? 175  TRP A CB  1 
ATOM   1289  C CG  . TRP A 1 196 ? 99.406  103.004 87.142  1.00 3.61  ? 175  TRP A CG  1 
ATOM   1290  C CD1 . TRP A 1 196 ? 99.269  104.299 86.754  1.00 3.61  ? 175  TRP A CD1 1 
ATOM   1291  C CD2 . TRP A 1 196 ? 98.145  102.612 87.688  1.00 3.61  ? 175  TRP A CD2 1 
ATOM   1292  N NE1 . TRP A 1 196 ? 98.001  104.745 87.034  1.00 3.61  ? 175  TRP A NE1 1 
ATOM   1293  C CE2 . TRP A 1 196 ? 97.290  103.722 87.605  1.00 3.61  ? 175  TRP A CE2 1 
ATOM   1294  C CE3 . TRP A 1 196 ? 97.656  101.427 88.242  1.00 3.61  ? 175  TRP A CE3 1 
ATOM   1295  C CZ2 . TRP A 1 196 ? 95.976  103.685 88.052  1.00 3.61  ? 175  TRP A CZ2 1 
ATOM   1296  C CZ3 . TRP A 1 196 ? 96.352  101.393 88.688  1.00 3.61  ? 175  TRP A CZ3 1 
ATOM   1297  C CH2 . TRP A 1 196 ? 95.527  102.513 88.591  1.00 3.61  ? 175  TRP A CH2 1 
ATOM   1298  N N   . LYS A 1 197 ? 103.569 101.158 86.350  1.00 2.47  ? 176  LYS A N   1 
ATOM   1299  C CA  . LYS A 1 197 ? 104.696 100.308 86.703  1.00 2.47  ? 176  LYS A CA  1 
ATOM   1300  C C   . LYS A 1 197 ? 106.040 100.971 86.447  1.00 2.47  ? 176  LYS A C   1 
ATOM   1301  O O   . LYS A 1 197 ? 107.010 100.670 87.147  1.00 2.47  ? 176  LYS A O   1 
ATOM   1302  C CB  . LYS A 1 197 ? 104.622 98.991  85.931  1.00 2.47  ? 176  LYS A CB  1 
ATOM   1303  C CG  . LYS A 1 197 ? 103.480 98.098  86.351  1.00 2.47  ? 176  LYS A CG  1 
ATOM   1304  C CD  . LYS A 1 197 ? 103.569 97.753  87.822  1.00 2.47  ? 176  LYS A CD  1 
ATOM   1305  C CE  . LYS A 1 197 ? 102.349 96.976  88.278  1.00 2.47  ? 176  LYS A CE  1 
ATOM   1306  N NZ  . LYS A 1 197 ? 101.168 97.865  88.413  1.00 2.47  ? 176  LYS A NZ  1 
ATOM   1307  N N   . LEU A 1 198 ? 106.119 101.870 85.465  1.00 2.10  ? 177  LEU A N   1 
ATOM   1308  C CA  . LEU A 1 198 ? 107.395 102.451 85.074  1.00 2.10  ? 177  LEU A CA  1 
ATOM   1309  C C   . LEU A 1 198 ? 107.808 103.605 85.970  1.00 2.10  ? 177  LEU A C   1 
ATOM   1310  O O   . LEU A 1 198 ? 109.000 103.781 86.235  1.00 2.10  ? 177  LEU A O   1 
ATOM   1311  C CB  . LEU A 1 198 ? 107.321 102.928 83.633  1.00 2.10  ? 177  LEU A CB  1 
ATOM   1312  C CG  . LEU A 1 198 ? 107.620 101.871 82.590  1.00 2.10  ? 177  LEU A CG  1 
ATOM   1313  C CD1 . LEU A 1 198 ? 107.702 102.534 81.246  1.00 2.10  ? 177  LEU A CD1 1 
ATOM   1314  C CD2 . LEU A 1 198 ? 108.915 101.188 82.935  1.00 2.10  ? 177  LEU A CD2 1 
ATOM   1315  N N   . ALA A 1 199 ? 106.860 104.420 86.419  1.00 1.79  ? 178  ALA A N   1 
ATOM   1316  C CA  . ALA A 1 199 ? 107.231 105.572 87.234  1.00 1.79  ? 178  ALA A CA  1 
ATOM   1317  C C   . ALA A 1 199 ? 107.963 105.169 88.505  1.00 1.79  ? 178  ALA A C   1 
ATOM   1318  O O   . ALA A 1 199 ? 109.071 105.683 88.736  1.00 1.79  ? 178  ALA A O   1 
ATOM   1319  C CB  . ALA A 1 199 ? 105.990 106.416 87.532  1.00 1.79  ? 178  ALA A CB  1 
ATOM   1320  N N   . PRO A 1 200 ? 107.452 104.261 89.344  1.00 1.90  ? 179  PRO A N   1 
ATOM   1321  C CA  . PRO A 1 200 ? 108.217 103.891 90.541  1.00 1.90  ? 179  PRO A CA  1 
ATOM   1322  C C   . PRO A 1 200 ? 109.486 103.135 90.224  1.00 1.90  ? 179  PRO A C   1 
ATOM   1323  O O   . PRO A 1 200 ? 110.452 103.224 90.987  1.00 1.90  ? 179  PRO A O   1 
ATOM   1324  C CB  . PRO A 1 200 ? 107.234 103.018 91.333  1.00 1.90  ? 179  PRO A CB  1 
ATOM   1325  C CG  . PRO A 1 200 ? 105.920 103.244 90.707  1.00 1.90  ? 179  PRO A CG  1 
ATOM   1326  C CD  . PRO A 1 200 ? 106.186 103.518 89.287  1.00 1.90  ? 179  PRO A CD  1 
ATOM   1327  N N   . ALA A 1 201 ? 109.511 102.386 89.126  1.00 1.86  ? 180  ALA A N   1 
ATOM   1328  C CA  . ALA A 1 201 ? 110.684 101.587 88.808  1.00 1.86  ? 180  ALA A CA  1 
ATOM   1329  C C   . ALA A 1 201 ? 111.866 102.460 88.411  1.00 1.86  ? 180  ALA A C   1 
ATOM   1330  O O   . ALA A 1 201 ? 112.995 102.208 88.839  1.00 1.86  ? 180  ALA A O   1 
ATOM   1331  C CB  . ALA A 1 201 ? 110.352 100.592 87.703  1.00 1.86  ? 180  ALA A CB  1 
ATOM   1332  N N   . ILE A 1 202 ? 111.638 103.489 87.595  1.00 1.66  ? 181  ILE A N   1 
ATOM   1333  C CA  . ILE A 1 202 ? 112.743 104.349 87.192  1.00 1.66  ? 181  ILE A CA  1 
ATOM   1334  C C   . ILE A 1 202 ? 112.951 105.516 88.151  1.00 1.66  ? 181  ILE A C   1 
ATOM   1335  O O   . ILE A 1 202 ? 114.020 106.140 88.128  1.00 1.66  ? 181  ILE A O   1 
ATOM   1336  C CB  . ILE A 1 202 ? 112.558 104.892 85.766  1.00 1.66  ? 181  ILE A CB  1 
ATOM   1337  C CG1 . ILE A 1 202 ? 111.376 105.854 85.709  1.00 1.66  ? 181  ILE A CG1 1 
ATOM   1338  C CG2 . ILE A 1 202 ? 112.333 103.752 84.803  1.00 1.66  ? 181  ILE A CG2 1 
ATOM   1339  C CD1 . ILE A 1 202 ? 111.294 106.645 84.436  1.00 1.66  ? 181  ILE A CD1 1 
ATOM   1340  N N   . ALA A 1 203 ? 111.966 105.837 88.990  1.00 1.58  ? 182  ALA A N   1 
ATOM   1341  C CA  . ALA A 1 203 ? 112.230 106.763 90.082  1.00 1.58  ? 182  ALA A CA  1 
ATOM   1342  C C   . ALA A 1 203 ? 113.234 106.169 91.054  1.00 1.58  ? 182  ALA A C   1 
ATOM   1343  O O   . ALA A 1 203 ? 114.085 106.879 91.595  1.00 1.58  ? 182  ALA A O   1 
ATOM   1344  C CB  . ALA A 1 203 ? 110.936 107.118 90.808  1.00 1.58  ? 182  ALA A CB  1 
ATOM   1345  N N   . ALA A 1 204 ? 113.161 104.861 91.269  1.00 1.99  ? 183  ALA A N   1 
ATOM   1346  C CA  . ALA A 1 204 ? 113.999 104.174 92.237  1.00 1.99  ? 183  ALA A CA  1 
ATOM   1347  C C   . ALA A 1 204 ? 115.370 103.812 91.692  1.00 1.99  ? 183  ALA A C   1 
ATOM   1348  O O   . ALA A 1 204 ? 116.175 103.242 92.429  1.00 1.99  ? 183  ALA A O   1 
ATOM   1349  C CB  . ALA A 1 204 ? 113.294 102.914 92.729  1.00 1.99  ? 183  ALA A CB  1 
ATOM   1350  N N   . GLY A 1 205 ? 115.663 104.132 90.440  1.00 2.47  ? 184  GLY A N   1 
ATOM   1351  C CA  . GLY A 1 205 ? 116.950 103.807 89.873  1.00 2.47  ? 184  GLY A CA  1 
ATOM   1352  C C   . GLY A 1 205 ? 117.057 102.418 89.299  1.00 2.47  ? 184  GLY A C   1 
ATOM   1353  O O   . GLY A 1 205 ? 118.174 101.920 89.128  1.00 2.47  ? 184  GLY A O   1 
ATOM   1354  N N   . ASN A 1 206 ? 115.937 101.773 89.000  1.00 2.64  ? 185  ASN A N   1 
ATOM   1355  C CA  . ASN A 1 206 ? 115.923 100.424 88.464  1.00 2.64  ? 185  ASN A CA  1 
ATOM   1356  C C   . ASN A 1 206 ? 115.797 100.488 86.953  1.00 2.64  ? 185  ASN A C   1 
ATOM   1357  O O   . ASN A 1 206 ? 114.938 101.200 86.430  1.00 2.64  ? 185  ASN A O   1 
ATOM   1358  C CB  . ASN A 1 206 ? 114.761 99.618  89.041  1.00 2.64  ? 185  ASN A CB  1 
ATOM   1359  C CG  . ASN A 1 206 ? 114.623 99.788  90.523  1.00 2.64  ? 185  ASN A CG  1 
ATOM   1360  O OD1 . ASN A 1 206 ? 113.584 100.203 91.021  1.00 2.64  ? 185  ASN A OD1 1 
ATOM   1361  N ND2 . ASN A 1 206 ? 115.679 99.481  91.242  1.00 2.64  ? 185  ASN A ND2 1 
ATOM   1362  N N   . CYS A 1 207 ? 116.654 99.758  86.257  1.00 3.46  ? 186  CYS A N   1 
ATOM   1363  C CA  . CYS A 1 207 ? 116.462 99.549  84.834  1.00 3.46  ? 186  CYS A CA  1 
ATOM   1364  C C   . CYS A 1 207 ? 115.366 98.521  84.619  1.00 3.46  ? 186  CYS A C   1 
ATOM   1365  O O   . CYS A 1 207 ? 115.251 97.552  85.368  1.00 3.46  ? 186  CYS A O   1 
ATOM   1366  C CB  . CYS A 1 207 ? 117.756 99.091  84.182  1.00 3.46  ? 186  CYS A CB  1 
ATOM   1367  S SG  . CYS A 1 207 ? 119.004 100.354 84.268  1.00 3.46  ? 186  CYS A SG  1 
ATOM   1368  N N   . VAL A 1 208 ? 114.557 98.736  83.592  1.00 2.33  ? 187  VAL A N   1 
ATOM   1369  C CA  . VAL A 1 208 ? 113.322 97.991  83.408  1.00 2.33  ? 187  VAL A CA  1 
ATOM   1370  C C   . VAL A 1 208 ? 113.380 97.255  82.085  1.00 2.33  ? 187  VAL A C   1 
ATOM   1371  O O   . VAL A 1 208 ? 113.753 97.836  81.062  1.00 2.33  ? 187  VAL A O   1 
ATOM   1372  C CB  . VAL A 1 208 ? 112.096 98.915  83.453  1.00 2.33  ? 187  VAL A CB  1 
ATOM   1373  C CG1 . VAL A 1 208 ? 110.842 98.116  83.247  1.00 2.33  ? 187  VAL A CG1 1 
ATOM   1374  C CG2 . VAL A 1 208 ? 112.045 99.642  84.765  1.00 2.33  ? 187  VAL A CG2 1 
ATOM   1375  N N   . VAL A 1 209 ? 113.027 95.978  82.111  1.00 2.64  ? 188  VAL A N   1 
ATOM   1376  C CA  . VAL A 1 209 ? 112.624 95.249  80.920  1.00 2.64  ? 188  VAL A CA  1 
ATOM   1377  C C   . VAL A 1 209 ? 111.116 95.103  80.994  1.00 2.64  ? 188  VAL A C   1 
ATOM   1378  O O   . VAL A 1 209 ? 110.586 94.597  81.990  1.00 2.64  ? 188  VAL A O   1 
ATOM   1379  C CB  . VAL A 1 209 ? 113.319 93.885  80.814  1.00 2.64  ? 188  VAL A CB  1 
ATOM   1380  C CG1 . VAL A 1 209 ? 112.981 93.241  79.490  1.00 2.64  ? 188  VAL A CG1 1 
ATOM   1381  C CG2 . VAL A 1 209 ? 114.814 94.057  80.952  1.00 2.64  ? 188  VAL A CG2 1 
ATOM   1382  N N   . LEU A 1 210 ? 110.426 95.570  79.960  1.00 5.12  ? 189  LEU A N   1 
ATOM   1383  C CA  . LEU A 1 210 ? 108.982 95.748  79.998  1.00 5.12  ? 189  LEU A CA  1 
ATOM   1384  C C   . LEU A 1 210 ? 108.347 94.926  78.890  1.00 5.12  ? 189  LEU A C   1 
ATOM   1385  O O   . LEU A 1 210 ? 108.681 95.098  77.715  1.00 5.12  ? 189  LEU A O   1 
ATOM   1386  C CB  . LEU A 1 210 ? 108.621 97.226  79.861  1.00 5.12  ? 189  LEU A CB  1 
ATOM   1387  C CG  . LEU A 1 210 ? 107.146 97.609  79.911  1.00 5.12  ? 189  LEU A CG  1 
ATOM   1388  C CD1 . LEU A 1 210 ? 106.530 97.196  81.225  1.00 5.12  ? 189  LEU A CD1 1 
ATOM   1389  C CD2 . LEU A 1 210 ? 107.023 99.098  79.726  1.00 5.12  ? 189  LEU A CD2 1 
ATOM   1390  N N   . LYS A 1 211 ? 107.433 94.041  79.267  1.00 6.94  ? 190  LYS A N   1 
ATOM   1391  C CA  . LYS A 1 211 ? 106.754 93.182  78.313  1.00 6.94  ? 190  LYS A CA  1 
ATOM   1392  C C   . LYS A 1 211 ? 105.334 93.684  78.108  1.00 6.94  ? 190  LYS A C   1 
ATOM   1393  O O   . LYS A 1 211 ? 104.530 93.632  79.048  1.00 6.94  ? 190  LYS A O   1 
ATOM   1394  C CB  . LYS A 1 211 ? 106.745 91.742  78.814  1.00 6.94  ? 190  LYS A CB  1 
ATOM   1395  C CG  . LYS A 1 211 ? 105.768 90.838  78.105  1.00 6.94  ? 190  LYS A CG  1 
ATOM   1396  C CD  . LYS A 1 211 ? 106.376 90.277  76.839  1.00 6.94  ? 190  LYS A CD  1 
ATOM   1397  C CE  . LYS A 1 211 ? 105.367 89.443  76.090  1.00 6.94  ? 190  LYS A CE  1 
ATOM   1398  N NZ  . LYS A 1 211 ? 104.366 90.288  75.394  1.00 6.94  ? 190  LYS A NZ  1 
ATOM   1399  N N   . PRO A 1 212 ? 104.983 94.195  76.929  1.00 8.00  ? 191  PRO A N   1 
ATOM   1400  C CA  . PRO A 1 212 ? 103.597 94.599  76.682  1.00 8.00  ? 191  PRO A CA  1 
ATOM   1401  C C   . PRO A 1 212 ? 102.732 93.397  76.349  1.00 8.00  ? 191  PRO A C   1 
ATOM   1402  O O   . PRO A 1 212 ? 103.188 92.431  75.733  1.00 8.00  ? 191  PRO A O   1 
ATOM   1403  C CB  . PRO A 1 212 ? 103.711 95.538  75.472  1.00 8.00  ? 191  PRO A CB  1 
ATOM   1404  C CG  . PRO A 1 212 ? 105.173 95.814  75.312  1.00 8.00  ? 191  PRO A CG  1 
ATOM   1405  C CD  . PRO A 1 212 ? 105.858 94.594  75.818  1.00 8.00  ? 191  PRO A CD  1 
ATOM   1406  N N   . ALA A 1 213 ? 101.469 93.462  76.753  1.00 8.94  ? 192  ALA A N   1 
ATOM   1407  C CA  . ALA A 1 213 ? 100.526 92.419  76.381  1.00 8.94  ? 192  ALA A CA  1 
ATOM   1408  C C   . ALA A 1 213 ? 100.322 92.436  74.875  1.00 8.94  ? 192  ALA A C   1 
ATOM   1409  O O   . ALA A 1 213 ? 100.114 93.496  74.282  1.00 8.94  ? 192  ALA A O   1 
ATOM   1410  C CB  . ALA A 1 213 ? 99.197  92.619  77.099  1.00 8.94  ? 192  ALA A CB  1 
ATOM   1411  N N   . GLU A 1 214 ? 100.372 91.257  74.254  1.00 11.06 ? 193  GLU A N   1 
ATOM   1412  C CA  . GLU A 1 214 ? 100.348 91.172  72.799  1.00 11.06 ? 193  GLU A CA  1 
ATOM   1413  C C   . GLU A 1 214 ? 99.019  91.605  72.197  1.00 11.06 ? 193  GLU A C   1 
ATOM   1414  O O   . GLU A 1 214 ? 98.936  91.771  70.977  1.00 11.06 ? 193  GLU A O   1 
ATOM   1415  C CB  . GLU A 1 214 ? 100.713 89.750  72.362  1.00 11.06 ? 193  GLU A CB  1 
ATOM   1416  C CG  . GLU A 1 214 ? 99.782  88.654  72.849  1.00 11.06 ? 193  GLU A CG  1 
ATOM   1417  C CD  . GLU A 1 214 ? 98.586  88.444  71.952  1.00 11.06 ? 193  GLU A CD  1 
ATOM   1418  O OE1 . GLU A 1 214 ? 98.641  88.863  70.778  1.00 11.06 ? 193  GLU A OE1 1 
ATOM   1419  O OE2 . GLU A 1 214 ? 97.594  87.846  72.418  1.00 11.06 ? 193  GLU A OE2 1 
ATOM   1420  N N   . GLN A 1 215 ? 97.982  91.788  73.014  1.00 9.86  ? 194  GLN A N   1 
ATOM   1421  C CA  . GLN A 1 215 ? 96.748  92.381  72.515  1.00 9.86  ? 194  GLN A CA  1 
ATOM   1422  C C   . GLN A 1 215 ? 96.952  93.842  72.133  1.00 9.86  ? 194  GLN A C   1 
ATOM   1423  O O   . GLN A 1 215 ? 96.406  94.306  71.125  1.00 9.86  ? 194  GLN A O   1 
ATOM   1424  C CB  . GLN A 1 215 ? 95.648  92.249  73.568  1.00 9.86  ? 194  GLN A CB  1 
ATOM   1425  C CG  . GLN A 1 215 ? 94.932  90.912  73.564  1.00 9.86  ? 194  GLN A CG  1 
ATOM   1426  C CD  . GLN A 1 215 ? 95.758  89.799  74.173  1.00 9.86  ? 194  GLN A CD  1 
ATOM   1427  O OE1 . GLN A 1 215 ? 96.961  89.942  74.382  1.00 9.86  ? 194  GLN A OE1 1 
ATOM   1428  N NE2 . GLN A 1 215 ? 95.114  88.678  74.459  1.00 9.86  ? 194  GLN A NE2 1 
ATOM   1429  N N   . THR A 1 216 ? 97.727  94.583  72.926  1.00 9.24  ? 195  THR A N   1 
ATOM   1430  C CA  . THR A 1 216 ? 97.914  96.024  72.754  1.00 9.24  ? 195  THR A CA  1 
ATOM   1431  C C   . THR A 1 216 ? 99.400  96.366  72.782  1.00 9.24  ? 195  THR A C   1 
ATOM   1432  O O   . THR A 1 216 ? 99.892  96.976  73.738  1.00 9.24  ? 195  THR A O   1 
ATOM   1433  C CB  . THR A 1 216 ? 97.172  96.800  73.843  1.00 9.24  ? 195  THR A CB  1 
ATOM   1434  O OG1 . THR A 1 216 ? 97.749  96.499  75.118  1.00 9.24  ? 195  THR A OG1 1 
ATOM   1435  C CG2 . THR A 1 216 ? 95.703  96.431  73.866  1.00 9.24  ? 195  THR A CG2 1 
ATOM   1436  N N   . PRO A 1 217 ? 100.148 95.989  71.747  1.00 10.83 ? 196  PRO A N   1 
ATOM   1437  C CA  . PRO A 1 217 ? 101.597 96.216  71.777  1.00 10.83 ? 196  PRO A CA  1 
ATOM   1438  C C   . PRO A 1 217 ? 102.033 97.603  71.328  1.00 10.83 ? 196  PRO A C   1 
ATOM   1439  O O   . PRO A 1 217 ? 103.081 98.089  71.760  1.00 10.83 ? 196  PRO A O   1 
ATOM   1440  C CB  . PRO A 1 217 ? 102.137 95.146  70.816  1.00 10.83 ? 196  PRO A CB  1 
ATOM   1441  C CG  . PRO A 1 217 ? 100.955 94.312  70.413  1.00 10.83 ? 196  PRO A CG  1 
ATOM   1442  C CD  . PRO A 1 217 ? 99.765  95.178  70.587  1.00 10.83 ? 196  PRO A CD  1 
ATOM   1443  N N   . ALA A 1 218 ? 101.254 98.251  70.465  1.00 10.61 ? 197  ALA A N   1 
ATOM   1444  C CA  . ALA A 1 218 ? 101.749 99.388  69.699  1.00 10.61 ? 197  ALA A CA  1 
ATOM   1445  C C   . ALA A 1 218 ? 101.517 100.742 70.359  1.00 10.61 ? 197  ALA A C   1 
ATOM   1446  O O   . ALA A 1 218 ? 101.913 101.759 69.787  1.00 10.61 ? 197  ALA A O   1 
ATOM   1447  C CB  . ALA A 1 218 ? 101.118 99.390  68.304  1.00 10.61 ? 197  ALA A CB  1 
ATOM   1448  N N   . GLY A 1 219 ? 100.894 100.798 71.534  1.00 8.05  ? 198  GLY A N   1 
ATOM   1449  C CA  . GLY A 1 219 ? 100.767 102.078 72.215  1.00 8.05  ? 198  GLY A CA  1 
ATOM   1450  C C   . GLY A 1 219 ? 102.029 102.450 72.970  1.00 8.05  ? 198  GLY A C   1 
ATOM   1451  O O   . GLY A 1 219 ? 102.511 103.588 72.895  1.00 8.05  ? 198  GLY A O   1 
ATOM   1452  N N   . ILE A 1 220 ? 102.583 101.486 73.708  1.00 6.76  ? 199  ILE A N   1 
ATOM   1453  C CA  . ILE A 1 220 ? 103.840 101.694 74.411  1.00 6.76  ? 199  ILE A CA  1 
ATOM   1454  C C   . ILE A 1 220 ? 104.956 102.028 73.433  1.00 6.76  ? 199  ILE A C   1 
ATOM   1455  O O   . ILE A 1 220 ? 105.876 102.774 73.769  1.00 6.76  ? 199  ILE A O   1 
ATOM   1456  C CB  . ILE A 1 220 ? 104.168 100.455 75.270  1.00 6.76  ? 199  ILE A CB  1 
ATOM   1457  C CG1 . ILE A 1 220 ? 105.300 100.748 76.252  1.00 6.76  ? 199  ILE A CG1 1 
ATOM   1458  C CG2 . ILE A 1 220 ? 104.498 99.263  74.404  1.00 6.76  ? 199  ILE A CG2 1 
ATOM   1459  C CD1 . ILE A 1 220 ? 104.943 101.756 77.295  1.00 6.76  ? 199  ILE A CD1 1 
ATOM   1460  N N   . MET A 1 221 ? 104.887 101.510 72.206  1.00 9.92  ? 200  MET A N   1 
ATOM   1461  C CA  . MET A 1 221 ? 105.873 101.866 71.190  1.00 9.92  ? 200  MET A CA  1 
ATOM   1462  C C   . MET A 1 221 ? 105.788 103.340 70.820  1.00 9.92  ? 200  MET A C   1 
ATOM   1463  O O   . MET A 1 221 ? 106.812 104.013 70.662  1.00 9.92  ? 200  MET A O   1 
ATOM   1464  C CB  . MET A 1 221 ? 105.678 101.000 69.949  1.00 9.92  ? 200  MET A CB  1 
ATOM   1465  C CG  . MET A 1 221 ? 105.948 99.525  70.135  1.00 9.92  ? 200  MET A CG  1 
ATOM   1466  S SD  . MET A 1 221 ? 107.654 99.214  70.598  1.00 9.92  ? 200  MET A SD  1 
ATOM   1467  C CE  . MET A 1 221 ? 107.472 98.926  72.336  1.00 9.92  ? 200  MET A CE  1 
ATOM   1468  N N   . VAL A 1 222 ? 104.572 103.849 70.637  1.00 6.69  ? 201  VAL A N   1 
ATOM   1469  C CA  . VAL A 1 222 ? 104.407 105.264 70.325  1.00 6.69  ? 201  VAL A CA  1 
ATOM   1470  C C   . VAL A 1 222 ? 104.927 106.120 71.470  1.00 6.69  ? 201  VAL A C   1 
ATOM   1471  O O   . VAL A 1 222 ? 105.663 107.092 71.260  1.00 6.69  ? 201  VAL A O   1 
ATOM   1472  C CB  . VAL A 1 222 ? 102.933 105.565 70.007  1.00 6.69  ? 201  VAL A CB  1 
ATOM   1473  C CG1 . VAL A 1 222 ? 102.655 107.047 70.133  1.00 6.69  ? 201  VAL A CG1 1 
ATOM   1474  C CG2 . VAL A 1 222 ? 102.589 105.068 68.618  1.00 6.69  ? 201  VAL A CG2 1 
ATOM   1475  N N   . TRP A 1 223 ? 104.583 105.749 72.702  1.00 4.83  ? 202  TRP A N   1 
ATOM   1476  C CA  . TRP A 1 223 ? 105.064 106.493 73.861  1.00 4.83  ? 202  TRP A CA  1 
ATOM   1477  C C   . TRP A 1 223 ? 106.587 106.437 73.972  1.00 4.83  ? 202  TRP A C   1 
ATOM   1478  O O   . TRP A 1 223 ? 107.233 107.434 74.322  1.00 4.83  ? 202  TRP A O   1 
ATOM   1479  C CB  . TRP A 1 223 ? 104.393 105.941 75.112  1.00 4.83  ? 202  TRP A CB  1 
ATOM   1480  C CG  . TRP A 1 223 ? 104.773 106.591 76.373  1.00 4.83  ? 202  TRP A CG  1 
ATOM   1481  C CD1 . TRP A 1 223 ? 104.300 107.764 76.861  1.00 4.83  ? 202  TRP A CD1 1 
ATOM   1482  C CD2 . TRP A 1 223 ? 105.675 106.080 77.350  1.00 4.83  ? 202  TRP A CD2 1 
ATOM   1483  N NE1 . TRP A 1 223 ? 104.867 108.031 78.077  1.00 4.83  ? 202  TRP A NE1 1 
ATOM   1484  C CE2 . TRP A 1 223 ? 105.717 107.009 78.400  1.00 4.83  ? 202  TRP A CE2 1 
ATOM   1485  C CE3 . TRP A 1 223 ? 106.463 104.931 77.433  1.00 4.83  ? 202  TRP A CE3 1 
ATOM   1486  C CZ2 . TRP A 1 223 ? 106.511 106.824 79.521  1.00 4.83  ? 202  TRP A CZ2 1 
ATOM   1487  C CZ3 . TRP A 1 223 ? 107.250 104.750 78.540  1.00 4.83  ? 202  TRP A CZ3 1 
ATOM   1488  C CH2 . TRP A 1 223 ? 107.273 105.692 79.572  1.00 4.83  ? 202  TRP A CH2 1 
ATOM   1489  N N   . ALA A 1 224 ? 107.180 105.287 73.659  1.00 5.11  ? 203  ALA A N   1 
ATOM   1490  C CA  . ALA A 1 224 ? 108.628 105.141 73.735  1.00 5.11  ? 203  ALA A CA  1 
ATOM   1491  C C   . ALA A 1 224 ? 109.328 105.986 72.682  1.00 5.11  ? 203  ALA A C   1 
ATOM   1492  O O   . ALA A 1 224 ? 110.284 106.702 72.991  1.00 5.11  ? 203  ALA A O   1 
ATOM   1493  C CB  . ALA A 1 224 ? 109.016 103.672 73.584  1.00 5.11  ? 203  ALA A CB  1 
ATOM   1494  N N   . ASN A 1 225 ? 108.877 105.919 71.426  1.00 5.34  ? 204  ASN A N   1 
ATOM   1495  C CA  . ASN A 1 225 ? 109.520 106.753 70.417  1.00 5.34  ? 204  ASN A CA  1 
ATOM   1496  C C   . ASN A 1 225 ? 109.258 108.227 70.669  1.00 5.34  ? 204  ASN A C   1 
ATOM   1497  O O   . ASN A 1 225 ? 110.009 109.071 70.173  1.00 5.34  ? 204  ASN A O   1 
ATOM   1498  C CB  . ASN A 1 225 ? 109.107 106.328 68.993  1.00 5.34  ? 204  ASN A CB  1 
ATOM   1499  C CG  . ASN A 1 225 ? 107.729 106.838 68.555  1.00 5.34  ? 204  ASN A CG  1 
ATOM   1500  O OD1 . ASN A 1 225 ? 107.164 107.779 69.106  1.00 5.34  ? 204  ASN A OD1 1 
ATOM   1501  N ND2 . ASN A 1 225 ? 107.185 106.191 67.534  1.00 5.34  ? 204  ASN A ND2 1 
ATOM   1502  N N   . LEU A 1 226 ? 108.211 108.551 71.430  1.00 4.00  ? 205  LEU A N   1 
ATOM   1503  C CA  . LEU A 1 226 ? 108.033 109.921 71.892  1.00 4.00  ? 205  LEU A CA  1 
ATOM   1504  C C   . LEU A 1 226 ? 109.133 110.314 72.866  1.00 4.00  ? 205  LEU A C   1 
ATOM   1505  O O   . LEU A 1 226 ? 109.869 111.278 72.633  1.00 4.00  ? 205  LEU A O   1 
ATOM   1506  C CB  . LEU A 1 226 ? 106.661 110.085 72.544  1.00 4.00  ? 205  LEU A CB  1 
ATOM   1507  C CG  . LEU A 1 226 ? 106.309 111.494 73.008  1.00 4.00  ? 205  LEU A CG  1 
ATOM   1508  C CD1 . LEU A 1 226 ? 105.998 112.373 71.817  1.00 4.00  ? 205  LEU A CD1 1 
ATOM   1509  C CD2 . LEU A 1 226 ? 105.143 111.459 73.972  1.00 4.00  ? 205  LEU A CD2 1 
ATOM   1510  N N   . ILE A 1 227 ? 109.271 109.572 73.965  1.00 3.11  ? 206  ILE A N   1 
ATOM   1511  C CA  . ILE A 1 227 ? 110.137 110.001 75.059  1.00 3.11  ? 206  ILE A CA  1 
ATOM   1512  C C   . ILE A 1 227 ? 111.446 109.216 75.115  1.00 3.11  ? 206  ILE A C   1 
ATOM   1513  O O   . ILE A 1 227 ? 112.196 109.350 76.084  1.00 3.11  ? 206  ILE A O   1 
ATOM   1514  C CB  . ILE A 1 227 ? 109.418 109.913 76.409  1.00 3.11  ? 206  ILE A CB  1 
ATOM   1515  C CG1 . ILE A 1 227 ? 109.352 108.464 76.866  1.00 3.11  ? 206  ILE A CG1 1 
ATOM   1516  C CG2 . ILE A 1 227 ? 108.021 110.477 76.302  1.00 3.11  ? 206  ILE A CG2 1 
ATOM   1517  C CD1 . ILE A 1 227 ? 109.219 108.334 78.339  1.00 3.11  ? 206  ILE A CD1 1 
ATOM   1518  N N   . GLY A 1 228 ? 111.757 108.425 74.095  1.00 3.50  ? 207  GLY A N   1 
ATOM   1519  C CA  . GLY A 1 228 ? 112.943 107.590 74.173  1.00 3.50  ? 207  GLY A CA  1 
ATOM   1520  C C   . GLY A 1 228 ? 114.237 108.336 73.921  1.00 3.50  ? 207  GLY A C   1 
ATOM   1521  O O   . GLY A 1 228 ? 115.141 107.830 73.252  1.00 3.50  ? 207  GLY A O   1 
ATOM   1522  N N   . ASP A 1 229 ? 114.332 109.547 74.460  1.00 3.43  ? 208  ASP A N   1 
ATOM   1523  C CA  . ASP A 1 229 ? 115.571 110.304 74.427  1.00 3.43  ? 208  ASP A CA  1 
ATOM   1524  C C   . ASP A 1 229 ? 115.813 111.090 75.707  1.00 3.43  ? 208  ASP A C   1 
ATOM   1525  O O   . ASP A 1 229 ? 116.813 111.808 75.787  1.00 3.43  ? 208  ASP A O   1 
ATOM   1526  C CB  . ASP A 1 229 ? 115.588 111.255 73.220  1.00 3.43  ? 208  ASP A CB  1 
ATOM   1527  C CG  . ASP A 1 229 ? 114.601 112.396 73.358  1.00 3.43  ? 208  ASP A CG  1 
ATOM   1528  O OD1 . ASP A 1 229 ? 113.403 112.194 73.065  1.00 3.43  ? 208  ASP A OD1 1 
ATOM   1529  O OD2 . ASP A 1 229 ? 115.026 113.501 73.752  1.00 3.43  ? 208  ASP A OD2 1 
ATOM   1530  N N   . LEU A 1 230 ? 114.942 110.977 76.705  1.00 2.83  ? 209  LEU A N   1 
ATOM   1531  C CA  . LEU A 1 230 ? 115.156 111.634 77.984  1.00 2.83  ? 209  LEU A CA  1 
ATOM   1532  C C   . LEU A 1 230 ? 115.827 110.729 79.000  1.00 2.83  ? 209  LEU A C   1 
ATOM   1533  O O   . LEU A 1 230 ? 116.481 111.230 79.920  1.00 2.83  ? 209  LEU A O   1 
ATOM   1534  C CB  . LEU A 1 230 ? 113.828 112.134 78.555  1.00 2.83  ? 209  LEU A CB  1 
ATOM   1535  C CG  . LEU A 1 230 ? 113.011 113.008 77.611  1.00 2.83  ? 209  LEU A CG  1 
ATOM   1536  C CD1 . LEU A 1 230 ? 111.839 113.608 78.335  1.00 2.83  ? 209  LEU A CD1 1 
ATOM   1537  C CD2 . LEU A 1 230 ? 113.881 114.099 77.033  1.00 2.83  ? 209  LEU A CD2 1 
ATOM   1538  N N   . LEU A 1 231 ? 115.685 109.418 78.852  1.00 2.50  ? 210  LEU A N   1 
ATOM   1539  C CA  . LEU A 1 231 ? 116.279 108.429 79.733  1.00 2.50  ? 210  LEU A CA  1 
ATOM   1540  C C   . LEU A 1 231 ? 117.575 107.904 79.137  1.00 2.50  ? 210  LEU A C   1 
ATOM   1541  O O   . LEU A 1 231 ? 117.680 107.759 77.915  1.00 2.50  ? 210  LEU A O   1 
ATOM   1542  C CB  . LEU A 1 231 ? 115.317 107.262 79.955  1.00 2.50  ? 210  LEU A CB  1 
ATOM   1543  C CG  . LEU A 1 231 ? 114.059 107.571 80.761  1.00 2.50  ? 210  LEU A CG  1 
ATOM   1544  C CD1 . LEU A 1 231 ? 113.028 106.484 80.560  1.00 2.50  ? 210  LEU A CD1 1 
ATOM   1545  C CD2 . LEU A 1 231 ? 114.404 107.717 82.220  1.00 2.50  ? 210  LEU A CD2 1 
ATOM   1546  N N   . PRO A 1 232 ? 118.575 107.637 79.969  1.00 2.58  ? 211  PRO A N   1 
ATOM   1547  C CA  . PRO A 1 232 ? 119.814 107.047 79.476  1.00 2.58  ? 211  PRO A CA  1 
ATOM   1548  C C   . PRO A 1 232 ? 119.548 105.706 78.822  1.00 2.58  ? 211  PRO A C   1 
ATOM   1549  O O   . PRO A 1 232 ? 118.647 104.972 79.249  1.00 2.58  ? 211  PRO A O   1 
ATOM   1550  C CB  . PRO A 1 232 ? 120.653 106.887 80.749  1.00 2.58  ? 211  PRO A CB  1 
ATOM   1551  C CG  . PRO A 1 232 ? 120.164 107.951 81.634  1.00 2.58  ? 211  PRO A CG  1 
ATOM   1552  C CD  . PRO A 1 232 ? 118.691 108.056 81.372  1.00 2.58  ? 211  PRO A CD  1 
ATOM   1553  N N   . PRO A 1 233 ? 120.292 105.364 77.774  1.00 3.09  ? 212  PRO A N   1 
ATOM   1554  C CA  . PRO A 1 233 ? 120.090 104.070 77.118  1.00 3.09  ? 212  PRO A CA  1 
ATOM   1555  C C   . PRO A 1 233 ? 120.181 102.921 78.109  1.00 3.09  ? 212  PRO A C   1 
ATOM   1556  O O   . PRO A 1 233 ? 121.148 102.801 78.864  1.00 3.09  ? 212  PRO A O   1 
ATOM   1557  C CB  . PRO A 1 233 ? 121.223 104.023 76.092  1.00 3.09  ? 212  PRO A CB  1 
ATOM   1558  C CG  . PRO A 1 233 ? 121.483 105.446 75.783  1.00 3.09  ? 212  PRO A CG  1 
ATOM   1559  C CD  . PRO A 1 233 ? 121.283 106.189 77.066  1.00 3.09  ? 212  PRO A CD  1 
ATOM   1560  N N   . GLY A 1 234 ? 119.153 102.077 78.110  1.00 3.10  ? 213  GLY A N   1 
ATOM   1561  C CA  . GLY A 1 234 ? 119.094 100.919 78.965  1.00 3.10  ? 213  GLY A CA  1 
ATOM   1562  C C   . GLY A 1 234 ? 118.233 101.083 80.196  1.00 3.10  ? 213  GLY A C   1 
ATOM   1563  O O   . GLY A 1 234 ? 117.877 100.081 80.820  1.00 3.10  ? 213  GLY A O   1 
ATOM   1564  N N   . VAL A 1 235 ? 117.892 102.314 80.567  1.00 2.72  ? 214  VAL A N   1 
ATOM   1565  C CA  . VAL A 1 235 ? 117.032 102.508 81.727  1.00 2.72  ? 214  VAL A CA  1 
ATOM   1566  C C   . VAL A 1 235 ? 115.640 101.964 81.452  1.00 2.72  ? 214  VAL A C   1 
ATOM   1567  O O   . VAL A 1 235 ? 114.989 101.409 82.342  1.00 2.72  ? 214  VAL A O   1 
ATOM   1568  C CB  . VAL A 1 235 ? 116.999 103.991 82.122  1.00 2.72  ? 214  VAL A CB  1 
ATOM   1569  C CG1 . VAL A 1 235 ? 116.092 104.198 83.315  1.00 2.72  ? 214  VAL A CG1 1 
ATOM   1570  C CG2 . VAL A 1 235 ? 118.394 104.458 82.435  1.00 2.72  ? 214  VAL A CG2 1 
ATOM   1571  N N   . LEU A 1 236 ? 115.166 102.101 80.220  1.00 3.49  ? 215  LEU A N   1 
ATOM   1572  C CA  . LEU A 1 236 ? 113.880 101.561 79.806  1.00 3.49  ? 215  LEU A CA  1 
ATOM   1573  C C   . LEU A 1 236 ? 114.089 100.686 78.584  1.00 3.49  ? 215  LEU A C   1 
ATOM   1574  O O   . LEU A 1 236 ? 114.572 101.162 77.554  1.00 3.49  ? 215  LEU A O   1 
ATOM   1575  C CB  . LEU A 1 236 ? 112.886 102.676 79.495  1.00 3.49  ? 215  LEU A CB  1 
ATOM   1576  C CG  . LEU A 1 236 ? 111.662 102.227 78.704  1.00 3.49  ? 215  LEU A CG  1 
ATOM   1577  C CD1 . LEU A 1 236 ? 110.667 101.583 79.633  1.00 3.49  ? 215  LEU A CD1 1 
ATOM   1578  C CD2 . LEU A 1 236 ? 111.039 103.398 77.979  1.00 3.49  ? 215  LEU A CD2 1 
ATOM   1579  N N   . ASN A 1 237 ? 113.731 99.413  78.704  1.00 3.72  ? 216  ASN A N   1 
ATOM   1580  C CA  . ASN A 1 237 ? 113.745 98.479  77.590  1.00 3.72  ? 216  ASN A CA  1 
ATOM   1581  C C   . ASN A 1 237 ? 112.374 97.841  77.505  1.00 3.72  ? 216  ASN A C   1 
ATOM   1582  O O   . ASN A 1 237 ? 111.838 97.386  78.517  1.00 3.72  ? 216  ASN A O   1 
ATOM   1583  C CB  . ASN A 1 237 ? 114.817 97.407  77.770  1.00 3.72  ? 216  ASN A CB  1 
ATOM   1584  C CG  . ASN A 1 237 ? 116.174 97.993  78.040  1.00 3.72  ? 216  ASN A CG  1 
ATOM   1585  O OD1 . ASN A 1 237 ? 116.848 98.469  77.132  1.00 3.72  ? 216  ASN A OD1 1 
ATOM   1586  N ND2 . ASN A 1 237 ? 116.579 97.981  79.299  1.00 3.72  ? 216  ASN A ND2 1 
ATOM   1587  N N   . ILE A 1 238 ? 111.805 97.812  76.307  1.00 5.13  ? 217  ILE A N   1 
ATOM   1588  C CA  . ILE A 1 238 ? 110.472 97.269  76.100  1.00 5.13  ? 217  ILE A CA  1 
ATOM   1589  C C   . ILE A 1 238 ? 110.563 96.199  75.026  1.00 5.13  ? 217  ILE A C   1 
ATOM   1590  O O   . ILE A 1 238 ? 110.971 96.484  73.895  1.00 5.13  ? 217  ILE A O   1 
ATOM   1591  C CB  . ILE A 1 238 ? 109.464 98.352  75.698  1.00 5.13  ? 217  ILE A CB  1 
ATOM   1592  C CG1 . ILE A 1 238 ? 109.259 99.335  76.846  1.00 5.13  ? 217  ILE A CG1 1 
ATOM   1593  C CG2 . ILE A 1 238 ? 108.152 97.710  75.403  1.00 5.13  ? 217  ILE A CG2 1 
ATOM   1594  C CD1 . ILE A 1 238 ? 109.005 100.743 76.396  1.00 5.13  ? 217  ILE A CD1 1 
ATOM   1595  N N   . VAL A 1 239 ? 110.176 94.977  75.373  1.00 8.29  ? 218  VAL A N   1 
ATOM   1596  C CA  . VAL A 1 239 ? 110.311 93.815  74.504  1.00 8.29  ? 218  VAL A CA  1 
ATOM   1597  C C   . VAL A 1 239 ? 108.930 93.209  74.312  1.00 8.29  ? 218  VAL A C   1 
ATOM   1598  O O   . VAL A 1 239 ? 108.320 92.732  75.276  1.00 8.29  ? 218  VAL A O   1 
ATOM   1599  C CB  . VAL A 1 239 ? 111.290 92.790  75.094  1.00 8.29  ? 218  VAL A CB  1 
ATOM   1600  C CG1 . VAL A 1 239 ? 111.098 91.446  74.453  1.00 8.29  ? 218  VAL A CG1 1 
ATOM   1601  C CG2 . VAL A 1 239 ? 112.716 93.260  74.902  1.00 8.29  ? 218  VAL A CG2 1 
ATOM   1602  N N   . ASN A 1 240 ? 108.447 93.207  73.073  1.00 13.04 ? 219  ASN A N   1 
ATOM   1603  C CA  . ASN A 1 240 ? 107.073 92.831  72.760  1.00 13.04 ? 219  ASN A CA  1 
ATOM   1604  C C   . ASN A 1 240 ? 107.026 91.436  72.154  1.00 13.04 ? 219  ASN A C   1 
ATOM   1605  O O   . ASN A 1 240 ? 107.794 91.125  71.241  1.00 13.04 ? 219  ASN A O   1 
ATOM   1606  C CB  . ASN A 1 240 ? 106.434 93.848  71.810  1.00 13.04 ? 219  ASN A CB  1 
ATOM   1607  C CG  . ASN A 1 240 ? 107.360 94.259  70.681  1.00 13.04 ? 219  ASN A CG  1 
ATOM   1608  O OD1 . ASN A 1 240 ? 108.375 93.614  70.426  1.00 13.04 ? 219  ASN A OD1 1 
ATOM   1609  N ND2 . ASN A 1 240 ? 107.019 95.347  70.004  1.00 13.04 ? 219  ASN A ND2 1 
ATOM   1610  N N   . GLY A 1 241 ? 106.125 90.606  72.661  1.00 14.07 ? 220  GLY A N   1 
ATOM   1611  C CA  . GLY A 1 241 ? 105.978 89.259  72.153  1.00 14.07 ? 220  GLY A CA  1 
ATOM   1612  C C   . GLY A 1 241 ? 104.747 88.602  72.735  1.00 14.07 ? 220  GLY A C   1 
ATOM   1613  O O   . GLY A 1 241 ? 103.893 89.259  73.329  1.00 14.07 ? 220  GLY A O   1 
ATOM   1614  N N   . PHE A 1 242 ? 104.660 87.289  72.551  1.00 15.42 ? 221  PHE A N   1 
ATOM   1615  C CA  . PHE A 1 242 ? 103.561 86.522  73.118  1.00 15.42 ? 221  PHE A CA  1 
ATOM   1616  C C   . PHE A 1 242 ? 103.867 86.137  74.558  1.00 15.42 ? 221  PHE A C   1 
ATOM   1617  O O   . PHE A 1 242 ? 105.015 85.853  74.907  1.00 15.42 ? 221  PHE A O   1 
ATOM   1618  C CB  . PHE A 1 242 ? 103.294 85.271  72.287  1.00 15.42 ? 221  PHE A CB  1 
ATOM   1619  C CG  . PHE A 1 242 ? 102.571 85.542  71.006  1.00 15.42 ? 221  PHE A CG  1 
ATOM   1620  C CD1 . PHE A 1 242 ? 101.295 86.067  71.018  1.00 15.42 ? 221  PHE A CD1 1 
ATOM   1621  C CD2 . PHE A 1 242 ? 103.171 85.282  69.789  1.00 15.42 ? 221  PHE A CD2 1 
ATOM   1622  C CE1 . PHE A 1 242 ? 100.625 86.317  69.841  1.00 15.42 ? 221  PHE A CE1 1 
ATOM   1623  C CE2 . PHE A 1 242 ? 102.504 85.531  68.612  1.00 15.42 ? 221  PHE A CE2 1 
ATOM   1624  C CZ  . PHE A 1 242 ? 101.230 86.052  68.638  1.00 15.42 ? 221  PHE A CZ  1 
ATOM   1625  N N   . GLY A 1 243 ? 102.823 86.111  75.390  1.00 16.38 ? 222  GLY A N   1 
ATOM   1626  C CA  . GLY A 1 243 ? 102.989 85.935  76.824  1.00 16.38 ? 222  GLY A CA  1 
ATOM   1627  C C   . GLY A 1 243 ? 103.631 84.625  77.232  1.00 16.38 ? 222  GLY A C   1 
ATOM   1628  O O   . GLY A 1 243 ? 104.082 84.496  78.374  1.00 16.38 ? 222  GLY A O   1 
ATOM   1629  N N   . LEU A 1 244 ? 103.673 83.644  76.335  1.00 15.80 ? 223  LEU A N   1 
ATOM   1630  C CA  . LEU A 1 244 ? 104.380 82.404  76.622  1.00 15.80 ? 223  LEU A CA  1 
ATOM   1631  C C   . LEU A 1 244 ? 105.763 82.360  75.990  1.00 15.80 ? 223  LEU A C   1 
ATOM   1632  O O   . LEU A 1 244 ? 106.678 81.760  76.564  1.00 15.80 ? 223  LEU A O   1 
ATOM   1633  C CB  . LEU A 1 244 ? 103.556 81.204  76.151  1.00 15.80 ? 223  LEU A CB  1 
ATOM   1634  C CG  . LEU A 1 244 ? 102.647 80.619  77.232  1.00 15.80 ? 223  LEU A CG  1 
ATOM   1635  C CD1 . LEU A 1 244 ? 101.791 79.490  76.686  1.00 15.80 ? 223  LEU A CD1 1 
ATOM   1636  C CD2 . LEU A 1 244 ? 103.477 80.148  78.417  1.00 15.80 ? 223  LEU A CD2 1 
ATOM   1637  N N   . GLU A 1 245 ? 105.937 82.986  74.826  1.00 17.90 ? 224  GLU A N   1 
ATOM   1638  C CA  . GLU A 1 245 ? 107.244 82.997  74.181  1.00 17.90 ? 224  GLU A CA  1 
ATOM   1639  C C   . GLU A 1 245 ? 108.193 83.981  74.850  1.00 17.90 ? 224  GLU A C   1 
ATOM   1640  O O   . GLU A 1 245 ? 109.404 83.744  74.889  1.00 17.90 ? 224  GLU A O   1 
ATOM   1641  C CB  . GLU A 1 245 ? 107.100 83.339  72.700  1.00 17.90 ? 224  GLU A CB  1 
ATOM   1642  C CG  . GLU A 1 245 ? 106.149 82.446  71.935  1.00 17.90 ? 224  GLU A CG  1 
ATOM   1643  C CD  . GLU A 1 245 ? 106.187 82.718  70.447  1.00 17.90 ? 224  GLU A CD  1 
ATOM   1644  O OE1 . GLU A 1 245 ? 106.919 83.640  70.033  1.00 17.90 ? 224  GLU A OE1 1 
ATOM   1645  O OE2 . GLU A 1 245 ? 105.489 82.012  69.691  1.00 17.90 ? 224  GLU A OE2 1 
ATOM   1646  N N   . ALA A 1 246 ? 107.671 85.092  75.366  1.00 14.51 ? 225  ALA A N   1 
ATOM   1647  C CA  . ALA A 1 246 ? 108.496 86.117  75.992  1.00 14.51 ? 225  ALA A CA  1 
ATOM   1648  C C   . ALA A 1 246 ? 108.163 86.380  77.451  1.00 14.51 ? 225  ALA A C   1 
ATOM   1649  O O   . ALA A 1 246 ? 109.036 86.833  78.188  1.00 14.51 ? 225  ALA A O   1 
ATOM   1650  C CB  . ALA A 1 246 ? 108.393 87.438  75.217  1.00 14.51 ? 225  ALA A CB  1 
ATOM   1651  N N   . GLY A 1 247 ? 106.931 86.123  77.888  1.00 12.60 ? 226  GLY A N   1 
ATOM   1652  C CA  . GLY A 1 247 ? 106.604 86.329  79.291  1.00 12.60 ? 226  GLY A CA  1 
ATOM   1653  C C   . GLY A 1 247 ? 107.332 85.364  80.207  1.00 12.60 ? 226  GLY A C   1 
ATOM   1654  O O   . GLY A 1 247 ? 107.851 85.752  81.258  1.00 12.60 ? 226  GLY A O   1 
ATOM   1655  N N   . LYS A 1 248 ? 107.367 84.085  79.824  1.00 13.51 ? 227  LYS A N   1 
ATOM   1656  C CA  . LYS A 1 248 ? 108.084 83.099  80.632  1.00 13.51 ? 227  LYS A CA  1 
ATOM   1657  C C   . LYS A 1 248 ? 109.582 83.373  80.691  1.00 13.51 ? 227  LYS A C   1 
ATOM   1658  O O   . LYS A 1 248 ? 110.136 83.394  81.803  1.00 13.51 ? 227  LYS A O   1 
ATOM   1659  C CB  . LYS A 1 248 ? 107.781 81.689  80.117  1.00 13.51 ? 227  LYS A CB  1 
ATOM   1660  C CG  . LYS A 1 248 ? 108.562 80.590  80.813  1.00 13.51 ? 227  LYS A CG  1 
ATOM   1661  C CD  . LYS A 1 248 ? 108.658 79.339  79.947  1.00 13.51 ? 227  LYS A CD  1 
ATOM   1662  C CE  . LYS A 1 248 ? 109.187 79.665  78.564  1.00 13.51 ? 227  LYS A CE  1 
ATOM   1663  N NZ  . LYS A 1 248 ? 110.579 80.184  78.616  1.00 13.51 ? 227  LYS A NZ  1 
ATOM   1664  N N   . PRO A 1 249 ? 110.295 83.590  79.576  1.00 12.40 ? 228  PRO A N   1 
ATOM   1665  C CA  . PRO A 1 249 ? 111.738 83.857  79.688  1.00 12.40 ? 228  PRO A CA  1 
ATOM   1666  C C   . PRO A 1 249 ? 112.061 85.074  80.526  1.00 12.40 ? 228  PRO A C   1 
ATOM   1667  O O   . PRO A 1 249 ? 113.122 85.115  81.160  1.00 12.40 ? 228  PRO A O   1 
ATOM   1668  C CB  . PRO A 1 249 ? 112.172 84.055  78.231  1.00 12.40 ? 228  PRO A CB  1 
ATOM   1669  C CG  . PRO A 1 249 ? 111.172 83.343  77.446  1.00 12.40 ? 228  PRO A CG  1 
ATOM   1670  C CD  . PRO A 1 249 ? 109.882 83.517  78.165  1.00 12.40 ? 228  PRO A CD  1 
ATOM   1671  N N   . LEU A 1 250 ? 111.188 86.078  80.536  1.00 11.06 ? 229  LEU A N   1 
ATOM   1672  C CA  . LEU A 1 250 ? 111.411 87.223  81.406  1.00 11.06 ? 229  LEU A CA  1 
ATOM   1673  C C   . LEU A 1 250 ? 111.164 86.857  82.861  1.00 11.06 ? 229  LEU A C   1 
ATOM   1674  O O   . LEU A 1 250 ? 111.953 87.219  83.738  1.00 11.06 ? 229  LEU A O   1 
ATOM   1675  C CB  . LEU A 1 250 ? 110.524 88.387  80.981  1.00 11.06 ? 229  LEU A CB  1 
ATOM   1676  C CG  . LEU A 1 250 ? 110.658 89.652  81.823  1.00 11.06 ? 229  LEU A CG  1 
ATOM   1677  C CD1 . LEU A 1 250 ? 112.042 90.226  81.657  1.00 11.06 ? 229  LEU A CD1 1 
ATOM   1678  C CD2 . LEU A 1 250 ? 109.608 90.660  81.421  1.00 11.06 ? 229  LEU A CD2 1 
ATOM   1679  N N   . ALA A 1 251 ? 110.077 86.136  83.140  1.00 11.86 ? 230  ALA A N   1 
ATOM   1680  C CA  . ALA A 1 251 ? 109.810 85.737  84.516  1.00 11.86 ? 230  ALA A CA  1 
ATOM   1681  C C   . ALA A 1 251 ? 110.766 84.648  84.987  1.00 11.86 ? 230  ALA A C   1 
ATOM   1682  O O   . ALA A 1 251 ? 111.115 84.605  86.171  1.00 11.86 ? 230  ALA A O   1 
ATOM   1683  C CB  . ALA A 1 251 ? 108.364 85.270  84.656  1.00 11.86 ? 230  ALA A CB  1 
ATOM   1684  N N   . SER A 1 252 ? 111.196 83.765  84.087  1.00 14.00 ? 231  SER A N   1 
ATOM   1685  C CA  . SER A 1 252 ? 112.116 82.681  84.437  1.00 14.00 ? 231  SER A CA  1 
ATOM   1686  C C   . SER A 1 252 ? 113.563 83.104  84.192  1.00 14.00 ? 231  SER A C   1 
ATOM   1687  O O   . SER A 1 252 ? 114.328 82.445  83.492  1.00 14.00 ? 231  SER A O   1 
ATOM   1688  C CB  . SER A 1 252 ? 111.779 81.422  83.650  1.00 14.00 ? 231  SER A CB  1 
ATOM   1689  O OG  . SER A 1 252 ? 110.477 80.969  83.948  1.00 14.00 ? 231  SER A OG  1 
ATOM   1690  N N   . SER A 1 253 ? 113.933 84.231  84.789  1.00 12.70 ? 232  SER A N   1 
ATOM   1691  C CA  . SER A 1 253 ? 115.287 84.744  84.669  1.00 12.70 ? 232  SER A CA  1 
ATOM   1692  C C   . SER A 1 253 ? 115.806 85.125  86.044  1.00 12.70 ? 232  SER A C   1 
ATOM   1693  O O   . SER A 1 253 ? 115.079 85.707  86.855  1.00 12.70 ? 232  SER A O   1 
ATOM   1694  C CB  . SER A 1 253 ? 115.352 85.953  83.734  1.00 12.70 ? 232  SER A CB  1 
ATOM   1695  O OG  . SER A 1 253 ? 116.686 86.205  83.341  1.00 12.70 ? 232  SER A OG  1 
ATOM   1696  N N   . ASN A 1 254 ? 117.064 84.782  86.303  1.00 12.41 ? 233  ASN A N   1 
ATOM   1697  C CA  . ASN A 1 254 ? 117.742 85.188  87.523  1.00 12.41 ? 233  ASN A CA  1 
ATOM   1698  C C   . ASN A 1 254 ? 118.383 86.566  87.416  1.00 12.41 ? 233  ASN A C   1 
ATOM   1699  O O   . ASN A 1 254 ? 118.916 87.062  88.413  1.00 12.41 ? 233  ASN A O   1 
ATOM   1700  C CB  . ASN A 1 254 ? 118.798 84.146  87.905  1.00 12.41 ? 233  ASN A CB  1 
ATOM   1701  C CG  . ASN A 1 254 ? 119.830 83.934  86.818  1.00 12.41 ? 233  ASN A CG  1 
ATOM   1702  O OD1 . ASN A 1 254 ? 119.829 84.620  85.799  1.00 12.41 ? 233  ASN A OD1 1 
ATOM   1703  N ND2 . ASN A 1 254 ? 120.722 82.976  87.031  1.00 12.41 ? 233  ASN A ND2 1 
ATOM   1704  N N   . ARG A 1 255 ? 118.342 87.191  86.240  1.00 8.15  ? 234  ARG A N   1 
ATOM   1705  C CA  . ARG A 1 255 ? 118.921 88.507  86.025  1.00 8.15  ? 234  ARG A CA  1 
ATOM   1706  C C   . ARG A 1 255 ? 117.943 89.636  86.304  1.00 8.15  ? 234  ARG A C   1 
ATOM   1707  O O   . ARG A 1 255 ? 118.175 90.765  85.862  1.00 8.15  ? 234  ARG A O   1 
ATOM   1708  C CB  . ARG A 1 255 ? 119.448 88.626  84.597  1.00 8.15  ? 234  ARG A CB  1 
ATOM   1709  C CG  . ARG A 1 255 ? 120.401 87.532  84.200  1.00 8.15  ? 234  ARG A CG  1 
ATOM   1710  C CD  . ARG A 1 255 ? 120.812 87.687  82.753  1.00 8.15  ? 234  ARG A CD  1 
ATOM   1711  N NE  . ARG A 1 255 ? 121.814 88.732  82.594  1.00 8.15  ? 234  ARG A NE  1 
ATOM   1712  C CZ  . ARG A 1 255 ? 122.079 89.338  81.444  1.00 8.15  ? 234  ARG A CZ  1 
ATOM   1713  N NH1 . ARG A 1 255 ? 121.416 89.000  80.350  1.00 8.15  ? 234  ARG A NH1 1 
ATOM   1714  N NH2 . ARG A 1 255 ? 123.009 90.278  81.389  1.00 8.15  ? 234  ARG A NH2 1 
ATOM   1715  N N   . ILE A 1 256 ? 116.852 89.362  87.009  1.00 6.61  ? 235  ILE A N   1 
ATOM   1716  C CA  . ILE A 1 256 ? 115.909 90.391  87.423  1.00 6.61  ? 235  ILE A CA  1 
ATOM   1717  C C   . ILE A 1 256 ? 115.749 90.287  88.927  1.00 6.61  ? 235  ILE A C   1 
ATOM   1718  O O   . ILE A 1 256 ? 115.676 89.183  89.472  1.00 6.61  ? 235  ILE A O   1 
ATOM   1719  C CB  . ILE A 1 256 ? 114.543 90.264  86.716  1.00 6.61  ? 235  ILE A CB  1 
ATOM   1720  C CG1 . ILE A 1 256 ? 113.845 88.962  87.094  1.00 6.61  ? 235  ILE A CG1 1 
ATOM   1721  C CG2 . ILE A 1 256 ? 114.705 90.346  85.211  1.00 6.61  ? 235  ILE A CG2 1 
ATOM   1722  C CD1 . ILE A 1 256 ? 112.418 88.885  86.629  1.00 6.61  ? 235  ILE A CD1 1 
ATOM   1723  N N   . ALA A 1 257 ? 115.732 91.426  89.600  1.00 4.80  ? 236  ALA A N   1 
ATOM   1724  C CA  . ALA A 1 257 ? 115.536 91.411  91.038  1.00 4.80  ? 236  ALA A CA  1 
ATOM   1725  C C   . ALA A 1 257 ? 114.069 91.324  91.425  1.00 4.80  ? 236  ALA A C   1 
ATOM   1726  O O   . ALA A 1 257 ? 113.767 91.237  92.619  1.00 4.80  ? 236  ALA A O   1 
ATOM   1727  C CB  . ALA A 1 257 ? 116.167 92.653  91.666  1.00 4.80  ? 236  ALA A CB  1 
ATOM   1728  N N   . LYS A 1 258 ? 113.161 91.335  90.456  1.00 5.09  ? 237  LYS A N   1 
ATOM   1729  C CA  . LYS A 1 258 ? 111.738 91.323  90.745  1.00 5.09  ? 237  LYS A CA  1 
ATOM   1730  C C   . LYS A 1 258 ? 110.967 91.123  89.453  1.00 5.09  ? 237  LYS A C   1 
ATOM   1731  O O   . LYS A 1 258 ? 111.431 91.506  88.377  1.00 5.09  ? 237  LYS A O   1 
ATOM   1732  C CB  . LYS A 1 258 ? 111.304 92.623  91.428  1.00 5.09  ? 237  LYS A CB  1 
ATOM   1733  C CG  . LYS A 1 258 ? 109.809 92.767  91.621  1.00 5.09  ? 237  LYS A CG  1 
ATOM   1734  C CD  . LYS A 1 258 ? 109.492 93.921  92.520  1.00 5.09  ? 237  LYS A CD  1 
ATOM   1735  C CE  . LYS A 1 258 ? 110.289 93.827  93.801  1.00 5.09  ? 237  LYS A CE  1 
ATOM   1736  N NZ  . LYS A 1 258 ? 110.437 92.454  94.329  1.00 5.09  ? 237  LYS A NZ  1 
ATOM   1737  N N   . ILE A 1 259 ? 109.795 90.507  89.572  1.00 6.37  ? 238  ILE A N   1 
ATOM   1738  C CA  . ILE A 1 259 ? 108.834 90.429  88.483  1.00 6.37  ? 238  ILE A CA  1 
ATOM   1739  C C   . ILE A 1 259 ? 107.518 91.019  88.971  1.00 6.37  ? 238  ILE A C   1 
ATOM   1740  O O   . ILE A 1 259 ? 107.049 90.699  90.072  1.00 6.37  ? 238  ILE A O   1 
ATOM   1741  C CB  . ILE A 1 259 ? 108.653 88.987  87.967  1.00 6.37  ? 238  ILE A CB  1 
ATOM   1742  C CG1 . ILE A 1 259 ? 107.720 88.962  86.756  1.00 6.37  ? 238  ILE A CG1 1 
ATOM   1743  C CG2 . ILE A 1 259 ? 108.149 88.068  89.061  1.00 6.37  ? 238  ILE A CG2 1 
ATOM   1744  C CD1 . ILE A 1 259 ? 108.356 89.460  85.487  1.00 6.37  ? 238  ILE A CD1 1 
ATOM   1745  N N   . ALA A 1 260 ? 106.956 91.919  88.175  1.00 6.57  ? 239  ALA A N   1 
ATOM   1746  C CA  . ALA A 1 260 ? 105.665 92.525  88.449  1.00 6.57  ? 239  ALA A CA  1 
ATOM   1747  C C   . ALA A 1 260 ? 104.673 92.058  87.398  1.00 6.57  ? 239  ALA A C   1 
ATOM   1748  O O   . ALA A 1 260 ? 105.010 91.960  86.217  1.00 6.57  ? 239  ALA A O   1 
ATOM   1749  C CB  . ALA A 1 260 ? 105.756 94.051  88.455  1.00 6.57  ? 239  ALA A CB  1 
ATOM   1750  N N   . PHE A 1 261 ? 103.455 91.756  87.833  1.00 12.54 ? 240  PHE A N   1 
ATOM   1751  C CA  . PHE A 1 261 ? 102.458 91.157  86.964  1.00 12.54 ? 240  PHE A CA  1 
ATOM   1752  C C   . PHE A 1 261 ? 101.078 91.714  87.268  1.00 12.54 ? 240  PHE A C   1 
ATOM   1753  O O   . PHE A 1 261 ? 100.736 91.960  88.427  1.00 12.54 ? 240  PHE A O   1 
ATOM   1754  C CB  . PHE A 1 261 ? 102.442 89.635  87.111  1.00 12.54 ? 240  PHE A CB  1 
ATOM   1755  C CG  . PHE A 1 261 ? 101.478 88.958  86.195  1.00 12.54 ? 240  PHE A CG  1 
ATOM   1756  C CD1 . PHE A 1 261 ? 101.783 88.774  84.861  1.00 12.54 ? 240  PHE A CD1 1 
ATOM   1757  C CD2 . PHE A 1 261 ? 100.258 88.516  86.665  1.00 12.54 ? 240  PHE A CD2 1 
ATOM   1758  C CE1 . PHE A 1 261 ? 100.890 88.161  84.021  1.00 12.54 ? 240  PHE A CE1 1 
ATOM   1759  C CE2 . PHE A 1 261 ? 99.368  87.901  85.830  1.00 12.54 ? 240  PHE A CE2 1 
ATOM   1760  C CZ  . PHE A 1 261 ? 99.678  87.729  84.509  1.00 12.54 ? 240  PHE A CZ  1 
ATOM   1761  N N   . THR A 1 262 ? 100.295 91.917  86.212  1.00 12.84 ? 241  THR A N   1 
ATOM   1762  C CA  . THR A 1 262 ? 98.882  92.253  86.323  1.00 12.84 ? 241  THR A CA  1 
ATOM   1763  C C   . THR A 1 262 ? 98.148  91.473  85.246  1.00 12.84 ? 241  THR A C   1 
ATOM   1764  O O   . THR A 1 262 ? 98.486  91.584  84.064  1.00 12.84 ? 241  THR A O   1 
ATOM   1765  C CB  . THR A 1 262 ? 98.649  93.759  86.165  1.00 12.84 ? 241  THR A CB  1 
ATOM   1766  O OG1 . THR A 1 262 ? 99.460  94.471  87.107  1.00 12.84 ? 241  THR A OG1 1 
ATOM   1767  C CG2 . THR A 1 262 ? 97.189  94.109  86.405  1.00 12.84 ? 241  THR A CG2 1 
ATOM   1768  N N   . GLY A 1 263 ? 97.163  90.674  85.645  1.00 16.35 ? 242  GLY A N   1 
ATOM   1769  C CA  . GLY A 1 263 ? 96.508  89.801  84.683  1.00 16.35 ? 242  GLY A CA  1 
ATOM   1770  C C   . GLY A 1 263 ? 95.646  88.760  85.363  1.00 16.35 ? 242  GLY A C   1 
ATOM   1771  O O   . GLY A 1 263 ? 95.127  88.981  86.462  1.00 16.35 ? 242  GLY A O   1 
ATOM   1772  N N   . GLU A 1 264 ? 95.496  87.623  84.690  1.00 19.68 ? 243  GLU A N   1 
ATOM   1773  C CA  . GLU A 1 264 ? 94.610  86.565  85.149  1.00 19.68 ? 243  GLU A CA  1 
ATOM   1774  C C   . GLU A 1 264 ? 95.294  85.695  86.198  1.00 19.68 ? 243  GLU A C   1 
ATOM   1775  O O   . GLU A 1 264 ? 96.518  85.549  86.214  1.00 19.68 ? 243  GLU A O   1 
ATOM   1776  C CB  . GLU A 1 264 ? 94.144  85.708  83.972  1.00 19.68 ? 243  GLU A CB  1 
ATOM   1777  C CG  . GLU A 1 264 ? 93.775  86.514  82.732  1.00 19.68 ? 243  GLU A CG  1 
ATOM   1778  C CD  . GLU A 1 264 ? 92.344  87.034  82.765  1.00 19.68 ? 243  GLU A CD  1 
ATOM   1779  O OE1 . GLU A 1 264 ? 91.483  86.382  83.393  1.00 19.68 ? 243  GLU A OE1 1 
ATOM   1780  O OE2 . GLU A 1 264 ? 92.079  88.095  82.160  1.00 19.68 ? 243  GLU A OE2 1 
ATOM   1781  N N   . THR A 1 265 ? 94.477  85.117  87.083  1.00 21.95 ? 244  THR A N   1 
ATOM   1782  C CA  . THR A 1 265 ? 95.009  84.376  88.222  1.00 21.95 ? 244  THR A CA  1 
ATOM   1783  C C   . THR A 1 265 ? 95.737  83.106  87.795  1.00 21.95 ? 244  THR A C   1 
ATOM   1784  O O   . THR A 1 265 ? 96.647  82.656  88.497  1.00 21.95 ? 244  THR A O   1 
ATOM   1785  C CB  . THR A 1 265 ? 93.882  84.039  89.195  1.00 21.95 ? 244  THR A CB  1 
ATOM   1786  O OG1 . THR A 1 265 ? 93.058  85.194  89.386  1.00 21.95 ? 244  THR A OG1 1 
ATOM   1787  C CG2 . THR A 1 265 ? 94.444  83.608  90.536  1.00 21.95 ? 244  THR A CG2 1 
ATOM   1788  N N   . THR A 1 266 ? 95.362  82.513  86.662  1.00 19.38 ? 245  THR A N   1 
ATOM   1789  C CA  . THR A 1 266 ? 96.094  81.350  86.170  1.00 19.38 ? 245  THR A CA  1 
ATOM   1790  C C   . THR A 1 266 ? 97.523  81.727  85.796  1.00 19.38 ? 245  THR A C   1 
ATOM   1791  O O   . THR A 1 266 ? 98.489  81.073  86.216  1.00 19.38 ? 245  THR A O   1 
ATOM   1792  C CB  . THR A 1 266 ? 95.364  80.741  84.971  1.00 19.38 ? 245  THR A CB  1 
ATOM   1793  O OG1 . THR A 1 266 ? 94.022  80.407  85.344  1.00 19.38 ? 245  THR A OG1 1 
ATOM   1794  C CG2 . THR A 1 266 ? 96.078  79.488  84.488  1.00 19.38 ? 245  THR A CG2 1 
ATOM   1795  N N   . THR A 1 267 ? 97.677  82.804  85.026  1.00 18.82 ? 246  THR A N   1 
ATOM   1796  C CA  . THR A 1 267 ? 99.012  83.288  84.713  1.00 18.82 ? 246  THR A CA  1 
ATOM   1797  C C   . THR A 1 267 ? 99.703  83.824  85.960  1.00 18.82 ? 246  THR A C   1 
ATOM   1798  O O   . THR A 1 267 ? 100.930 83.761  86.062  1.00 18.82 ? 246  THR A O   1 
ATOM   1799  C CB  . THR A 1 267 ? 98.940  84.364  83.632  1.00 18.82 ? 246  THR A CB  1 
ATOM   1800  O OG1 . THR A 1 267 ? 98.181  83.869  82.525  1.00 18.82 ? 246  THR A OG1 1 
ATOM   1801  C CG2 . THR A 1 267 ? 100.333 84.684  83.127  1.00 18.82 ? 246  THR A CG2 1 
ATOM   1802  N N   . GLY A 1 268 ? 98.937  84.342  86.921  1.00 19.26 ? 247  GLY A N   1 
ATOM   1803  C CA  . GLY A 1 268 ? 99.537  84.772  88.174  1.00 19.26 ? 247  GLY A CA  1 
ATOM   1804  C C   . GLY A 1 268 ? 100.173 83.625  88.935  1.00 19.26 ? 247  GLY A C   1 
ATOM   1805  O O   . GLY A 1 268 ? 101.289 83.747  89.445  1.00 19.26 ? 247  GLY A O   1 
ATOM   1806  N N   . ARG A 1 269 ? 99.475  82.490  89.010  1.00 22.14 ? 248  ARG A N   1 
ATOM   1807  C CA  . ARG A 1 269 ? 100.044 81.303  89.636  1.00 22.14 ? 248  ARG A CA  1 
ATOM   1808  C C   . ARG A 1 269 ? 101.242 80.789  88.852  1.00 22.14 ? 248  ARG A C   1 
ATOM   1809  O O   . ARG A 1 269 ? 102.247 80.373  89.443  1.00 22.14 ? 248  ARG A O   1 
ATOM   1810  C CB  . ARG A 1 269 ? 98.982  80.215  89.763  1.00 22.14 ? 248  ARG A CB  1 
ATOM   1811  C CG  . ARG A 1 269 ? 97.920  80.530  90.793  1.00 22.14 ? 248  ARG A CG  1 
ATOM   1812  C CD  . ARG A 1 269 ? 97.075  79.324  91.120  1.00 22.14 ? 248  ARG A CD  1 
ATOM   1813  N NE  . ARG A 1 269 ? 96.351  79.532  92.367  1.00 22.14 ? 248  ARG A NE  1 
ATOM   1814  C CZ  . ARG A 1 269 ? 95.121  80.024  92.440  1.00 22.14 ? 248  ARG A CZ  1 
ATOM   1815  N NH1 . ARG A 1 269 ? 94.470  80.348  91.332  1.00 22.14 ? 248  ARG A NH1 1 
ATOM   1816  N NH2 . ARG A 1 269 ? 94.540  80.186  93.620  1.00 22.14 ? 248  ARG A NH2 1 
ATOM   1817  N N   . LEU A 1 270 ? 101.157 80.806  87.521  1.00 21.01 ? 249  LEU A N   1 
ATOM   1818  C CA  . LEU A 1 270 ? 102.309 80.409  86.720  1.00 21.01 ? 249  LEU A CA  1 
ATOM   1819  C C   . LEU A 1 270 ? 103.526 81.265  87.053  1.00 21.01 ? 249  LEU A C   1 
ATOM   1820  O O   . LEU A 1 270 ? 104.603 80.739  87.361  1.00 21.01 ? 249  LEU A O   1 
ATOM   1821  C CB  . LEU A 1 270 ? 101.976 80.503  85.232  1.00 21.01 ? 249  LEU A CB  1 
ATOM   1822  C CG  . LEU A 1 270 ? 101.208 79.319  84.651  1.00 21.01 ? 249  LEU A CG  1 
ATOM   1823  C CD1 . LEU A 1 270 ? 100.467 79.734  83.394  1.00 21.01 ? 249  LEU A CD1 1 
ATOM   1824  C CD2 . LEU A 1 270 ? 102.154 78.166  84.366  1.00 21.01 ? 249  LEU A CD2 1 
ATOM   1825  N N   . ILE A 1 271 ? 103.360 82.589  87.023  1.00 20.34 ? 250  ILE A N   1 
ATOM   1826  C CA  . ILE A 1 271 ? 104.477 83.500  87.259  1.00 20.34 ? 250  ILE A CA  1 
ATOM   1827  C C   . ILE A 1 271 ? 105.015 83.321  88.669  1.00 20.34 ? 250  ILE A C   1 
ATOM   1828  O O   . ILE A 1 271 ? 106.231 83.372  88.896  1.00 20.34 ? 250  ILE A O   1 
ATOM   1829  C CB  . ILE A 1 271 ? 104.049 84.957  86.990  1.00 20.34 ? 250  ILE A CB  1 
ATOM   1830  C CG1 . ILE A 1 271 ? 103.759 85.176  85.501  1.00 20.34 ? 250  ILE A CG1 1 
ATOM   1831  C CG2 . ILE A 1 271 ? 105.113 85.927  87.456  1.00 20.34 ? 250  ILE A CG2 1 
ATOM   1832  C CD1 . ILE A 1 271 ? 104.760 84.538  84.570  1.00 20.34 ? 250  ILE A CD1 1 
ATOM   1833  N N   . MET A 1 272 ? 104.123 83.108  89.641  1.00 24.13 ? 251  MET A N   1 
ATOM   1834  C CA  . MET A 1 272 ? 104.567 82.804  90.995  1.00 24.13 ? 251  MET A CA  1 
ATOM   1835  C C   . MET A 1 272 ? 105.447 81.565  91.011  1.00 24.13 ? 251  MET A C   1 
ATOM   1836  O O   . MET A 1 272 ? 106.477 81.540  91.687  1.00 24.13 ? 251  MET A O   1 
ATOM   1837  C CB  . MET A 1 272 ? 103.364 82.618  91.917  1.00 24.13 ? 251  MET A CB  1 
ATOM   1838  C CG  . MET A 1 272 ? 102.874 83.904  92.548  1.00 24.13 ? 251  MET A CG  1 
ATOM   1839  S SD  . MET A 1 272 ? 103.776 84.350  94.041  1.00 24.13 ? 251  MET A SD  1 
ATOM   1840  C CE  . MET A 1 272 ? 103.388 82.964  95.101  1.00 24.13 ? 251  MET A CE  1 
ATOM   1841  N N   . GLN A 1 273 ? 105.071 80.536  90.250  1.00 24.74 ? 252  GLN A N   1 
ATOM   1842  C CA  . GLN A 1 273 ? 105.915 79.347  90.148  1.00 24.74 ? 252  GLN A CA  1 
ATOM   1843  C C   . GLN A 1 273 ? 107.295 79.687  89.591  1.00 24.74 ? 252  GLN A C   1 
ATOM   1844  O O   . GLN A 1 273 ? 108.322 79.382  90.219  1.00 24.74 ? 252  GLN A O   1 
ATOM   1845  C CB  . GLN A 1 273 ? 105.236 78.298  89.267  1.00 24.74 ? 252  GLN A CB  1 
ATOM   1846  C CG  . GLN A 1 273 ? 103.966 77.693  89.841  1.00 24.74 ? 252  GLN A CG  1 
ATOM   1847  C CD  . GLN A 1 273 ? 104.220 76.858  91.073  1.00 24.74 ? 252  GLN A CD  1 
ATOM   1848  O OE1 . GLN A 1 273 ? 103.839 77.230  92.176  1.00 24.74 ? 252  GLN A OE1 1 
ATOM   1849  N NE2 . GLN A 1 273 ? 104.862 75.710  90.887  1.00 24.74 ? 252  GLN A NE2 1 
ATOM   1850  N N   . TYR A 1 274 ? 107.341 80.334  88.419  1.00 22.24 ? 253  TYR A N   1 
ATOM   1851  C CA  . TYR A 1 274 ? 108.637 80.561  87.778  1.00 22.24 ? 253  TYR A CA  1 
ATOM   1852  C C   . TYR A 1 274 ? 109.534 81.443  88.635  1.00 22.24 ? 253  TYR A C   1 
ATOM   1853  O O   . TYR A 1 274 ? 110.747 81.219  88.708  1.00 22.24 ? 253  TYR A O   1 
ATOM   1854  C CB  . TYR A 1 274 ? 108.522 81.191  86.386  1.00 22.24 ? 253  TYR A CB  1 
ATOM   1855  C CG  . TYR A 1 274 ? 107.519 80.621  85.412  1.00 22.24 ? 253  TYR A CG  1 
ATOM   1856  C CD1 . TYR A 1 274 ? 107.866 79.581  84.560  1.00 22.24 ? 253  TYR A CD1 1 
ATOM   1857  C CD2 . TYR A 1 274 ? 106.298 81.236  85.217  1.00 22.24 ? 253  TYR A CD2 1 
ATOM   1858  C CE1 . TYR A 1 274 ? 106.970 79.087  83.636  1.00 22.24 ? 253  TYR A CE1 1 
ATOM   1859  C CE2 . TYR A 1 274 ? 105.393 80.753  84.300  1.00 22.24 ? 253  TYR A CE2 1 
ATOM   1860  C CZ  . TYR A 1 274 ? 105.735 79.683  83.505  1.00 22.24 ? 253  TYR A CZ  1 
ATOM   1861  O OH  . TYR A 1 274 ? 104.834 79.209  82.580  1.00 22.24 ? 253  TYR A OH  1 
ATOM   1862  N N   . ALA A 1 275 ? 108.966 82.457  89.277  1.00 21.81 ? 254  ALA A N   1 
ATOM   1863  C CA  . ALA A 1 275 ? 109.755 83.383  90.072  1.00 21.81 ? 254  ALA A CA  1 
ATOM   1864  C C   . ALA A 1 275 ? 109.944 82.922  91.509  1.00 21.81 ? 254  ALA A C   1 
ATOM   1865  O O   . ALA A 1 275 ? 110.664 83.581  92.266  1.00 21.81 ? 254  ALA A O   1 
ATOM   1866  C CB  . ALA A 1 275 ? 109.112 84.767  90.048  1.00 21.81 ? 254  ALA A CB  1 
ATOM   1867  N N   . SER A 1 276 ? 109.307 81.823  91.909  1.00 25.16 ? 255  SER A N   1 
ATOM   1868  C CA  . SER A 1 276 ? 109.657 81.190  93.170  1.00 25.16 ? 255  SER A CA  1 
ATOM   1869  C C   . SER A 1 276 ? 110.774 80.179  92.987  1.00 25.16 ? 255  SER A C   1 
ATOM   1870  O O   . SER A 1 276 ? 111.507 79.894  93.939  1.00 25.16 ? 255  SER A O   1 
ATOM   1871  C CB  . SER A 1 276 ? 108.434 80.511  93.785  1.00 25.16 ? 255  SER A CB  1 
ATOM   1872  O OG  . SER A 1 276 ? 108.006 79.420  92.989  1.00 25.16 ? 255  SER A OG  1 
ATOM   1873  N N   . GLU A 1 277 ? 110.922 79.628  91.781  1.00 23.38 ? 256  GLU A N   1 
ATOM   1874  C CA  . GLU A 1 277 ? 112.064 78.745  91.555  1.00 23.38 ? 256  GLU A CA  1 
ATOM   1875  C C   . GLU A 1 277 ? 113.389 79.501  91.548  1.00 23.38 ? 256  GLU A C   1 
ATOM   1876  O O   . GLU A 1 277 ? 114.449 78.865  91.551  1.00 23.38 ? 256  GLU A O   1 
ATOM   1877  C CB  . GLU A 1 277 ? 111.915 77.964  90.248  1.00 23.38 ? 256  GLU A CB  1 
ATOM   1878  C CG  . GLU A 1 277 ? 110.521 77.434  89.959  1.00 23.38 ? 256  GLU A CG  1 
ATOM   1879  C CD  . GLU A 1 277 ? 110.010 76.423  90.979  1.00 23.38 ? 256  GLU A CD  1 
ATOM   1880  O OE1 . GLU A 1 277 ? 110.787 75.974  91.847  1.00 23.38 ? 256  GLU A OE1 1 
ATOM   1881  O OE2 . GLU A 1 277 ? 108.811 76.076  90.911  1.00 23.38 ? 256  GLU A OE2 1 
ATOM   1882  N N   . ASN A 1 278 ? 113.360 80.833  91.532  1.00 22.74 ? 257  ASN A N   1 
ATOM   1883  C CA  . ASN A 1 278 ? 114.567 81.648  91.453  1.00 22.74 ? 257  ASN A CA  1 
ATOM   1884  C C   . ASN A 1 278 ? 114.785 82.529  92.673  1.00 22.74 ? 257  ASN A C   1 
ATOM   1885  O O   . ASN A 1 278 ? 115.793 83.239  92.726  1.00 22.74 ? 257  ASN A O   1 
ATOM   1886  C CB  . ASN A 1 278 ? 114.534 82.528  90.199  1.00 22.74 ? 257  ASN A CB  1 
ATOM   1887  C CG  . ASN A 1 278 ? 115.308 81.928  89.044  1.00 22.74 ? 257  ASN A CG  1 
ATOM   1888  O OD1 . ASN A 1 278 ? 116.518 81.728  89.130  1.00 22.74 ? 257  ASN A OD1 1 
ATOM   1889  N ND2 . ASN A 1 278 ? 114.611 81.639  87.952  1.00 22.74 ? 257  ASN A ND2 1 
ATOM   1890  N N   . LEU A 1 279 ? 113.860 82.526  93.631  1.00 19.76 ? 258  LEU A N   1 
ATOM   1891  C CA  . LEU A 1 279 ? 113.919 83.270  94.887  1.00 19.76 ? 258  LEU A CA  1 
ATOM   1892  C C   . LEU A 1 279 ? 113.654 84.760  94.717  1.00 19.76 ? 258  LEU A C   1 
ATOM   1893  O O   . LEU A 1 279 ? 113.665 85.489  95.715  1.00 19.76 ? 258  LEU A O   1 
ATOM   1894  C CB  . LEU A 1 279 ? 115.258 83.087  95.620  1.00 19.76 ? 258  LEU A CB  1 
ATOM   1895  C CG  . LEU A 1 279 ? 115.418 81.900  96.571  1.00 19.76 ? 258  LEU A CG  1 
ATOM   1896  C CD1 . LEU A 1 279 ? 114.524 82.075  97.778  1.00 19.76 ? 258  LEU A CD1 1 
ATOM   1897  C CD2 . LEU A 1 279 ? 115.093 80.607  95.869  1.00 19.76 ? 258  LEU A CD2 1 
ATOM   1898  N N   . ILE A 1 280 ? 113.407 85.236  93.502  1.00 13.67 ? 259  ILE A N   1 
ATOM   1899  C CA  . ILE A 1 280 ? 113.123 86.650  93.264  1.00 13.67 ? 259  ILE A CA  1 
ATOM   1900  C C   . ILE A 1 280 ? 111.702 86.966  93.717  1.00 13.67 ? 259  ILE A C   1 
ATOM   1901  O O   . ILE A 1 280 ? 110.774 86.201  93.422  1.00 13.67 ? 259  ILE A O   1 
ATOM   1902  C CB  . ILE A 1 280 ? 113.337 87.015  91.788  1.00 13.67 ? 259  ILE A CB  1 
ATOM   1903  C CG1 . ILE A 1 280 ? 112.530 86.089  90.882  1.00 13.67 ? 259  ILE A CG1 1 
ATOM   1904  C CG2 . ILE A 1 280 ? 114.797 86.913  91.440  1.00 13.67 ? 259  ILE A CG2 1 
ATOM   1905  C CD1 . ILE A 1 280 ? 112.617 86.436  89.425  1.00 13.67 ? 259  ILE A CD1 1 
ATOM   1906  N N   . PRO A 1 281 ? 111.486 88.062  94.440  1.00 11.86 ? 260  PRO A N   1 
ATOM   1907  C CA  . PRO A 1 281 ? 110.131 88.394  94.892  1.00 11.86 ? 260  PRO A CA  1 
ATOM   1908  C C   . PRO A 1 281 ? 109.209 88.696  93.721  1.00 11.86 ? 260  PRO A C   1 
ATOM   1909  O O   . PRO A 1 281 ? 109.640 89.091  92.636  1.00 11.86 ? 260  PRO A O   1 
ATOM   1910  C CB  . PRO A 1 281 ? 110.339 89.633  95.770  1.00 11.86 ? 260  PRO A CB  1 
ATOM   1911  C CG  . PRO A 1 281 ? 111.777 89.618  96.130  1.00 11.86 ? 260  PRO A CG  1 
ATOM   1912  C CD  . PRO A 1 281 ? 112.493 88.985  94.985  1.00 11.86 ? 260  PRO A CD  1 
ATOM   1913  N N   . VAL A 1 282 ? 107.915 88.495  93.954  1.00 12.48 ? 261  VAL A N   1 
ATOM   1914  C CA  . VAL A 1 282 ? 106.889 88.661  92.934  1.00 12.48 ? 261  VAL A CA  1 
ATOM   1915  C C   . VAL A 1 282 ? 105.888 89.693  93.424  1.00 12.48 ? 261  VAL A C   1 
ATOM   1916  O O   . VAL A 1 282 ? 105.621 89.786  94.627  1.00 12.48 ? 261  VAL A O   1 
ATOM   1917  C CB  . VAL A 1 282 ? 106.173 87.331  92.626  1.00 12.48 ? 261  VAL A CB  1 
ATOM   1918  C CG1 . VAL A 1 282 ? 105.366 87.445  91.352  1.00 12.48 ? 261  VAL A CG1 1 
ATOM   1919  C CG2 . VAL A 1 282 ? 107.166 86.200  92.542  1.00 12.48 ? 261  VAL A CG2 1 
ATOM   1920  N N   . THR A 1 283 ? 105.332 90.470  92.498  1.00 11.66 ? 262  THR A N   1 
ATOM   1921  C CA  . THR A 1 283 ? 104.276 91.424  92.831  1.00 11.66 ? 262  THR A CA  1 
ATOM   1922  C C   . THR A 1 283 ? 103.153 91.269  91.810  1.00 11.66 ? 262  THR A C   1 
ATOM   1923  O O   . THR A 1 283 ? 103.258 91.773  90.690  1.00 11.66 ? 262  THR A O   1 
ATOM   1924  C CB  . THR A 1 283 ? 104.814 92.852  92.855  1.00 11.66 ? 262  THR A CB  1 
ATOM   1925  O OG1 . THR A 1 283 ? 105.958 92.917  93.714  1.00 11.66 ? 262  THR A OG1 1 
ATOM   1926  C CG2 . THR A 1 283 ? 103.760 93.816  93.368  1.00 11.66 ? 262  THR A CG2 1 
ATOM   1927  N N   . LEU A 1 284 ? 102.081 90.585  92.198  1.00 15.46 ? 263  LEU A N   1 
ATOM   1928  C CA  . LEU A 1 284 ? 100.933 90.360  91.331  1.00 15.46 ? 263  LEU A CA  1 
ATOM   1929  C C   . LEU A 1 284 ? 99.826  91.369  91.604  1.00 15.46 ? 263  LEU A C   1 
ATOM   1930  O O   . LEU A 1 284 ? 99.766  92.003  92.659  1.00 15.46 ? 263  LEU A O   1 
ATOM   1931  C CB  . LEU A 1 284 ? 100.374 88.947  91.511  1.00 15.46 ? 263  LEU A CB  1 
ATOM   1932  C CG  . LEU A 1 284 ? 101.310 87.744  91.522  1.00 15.46 ? 263  LEU A CG  1 
ATOM   1933  C CD1 . LEU A 1 284 ? 100.499 86.506  91.812  1.00 15.46 ? 263  LEU A CD1 1 
ATOM   1934  C CD2 . LEU A 1 284 ? 102.018 87.606  90.193  1.00 15.46 ? 263  LEU A CD2 1 
ATOM   1935  N N   . GLU A 1 285 ? 98.941  91.510  90.619  1.00 17.49 ? 264  GLU A N   1 
ATOM   1936  C CA  . GLU A 1 285 ? 97.689  92.260  90.757  1.00 17.49 ? 264  GLU A CA  1 
ATOM   1937  C C   . GLU A 1 285 ? 96.682  91.581  89.832  1.00 17.49 ? 264  GLU A C   1 
ATOM   1938  O O   . GLU A 1 285 ? 96.613  91.886  88.640  1.00 17.49 ? 264  GLU A O   1 
ATOM   1939  C CB  . GLU A 1 285 ? 97.875  93.730  90.419  1.00 17.49 ? 264  GLU A CB  1 
ATOM   1940  C CG  . GLU A 1 285 ? 96.728  94.622  90.851  1.00 17.49 ? 264  GLU A CG  1 
ATOM   1941  C CD  . GLU A 1 285 ? 96.838  95.070  92.296  1.00 17.49 ? 264  GLU A CD  1 
ATOM   1942  O OE1 . GLU A 1 285 ? 97.816  94.687  92.973  1.00 17.49 ? 264  GLU A OE1 1 
ATOM   1943  O OE2 . GLU A 1 285 ? 95.962  95.836  92.743  1.00 17.49 ? 264  GLU A OE2 1 
ATOM   1944  N N   . LEU A 1 286 ? 95.901  90.667  90.388  1.00 19.77 ? 265  LEU A N   1 
ATOM   1945  C CA  . LEU A 1 286 ? 95.019  89.825  89.597  1.00 19.77 ? 265  LEU A CA  1 
ATOM   1946  C C   . LEU A 1 286 ? 93.587  90.339  89.651  1.00 19.77 ? 265  LEU A C   1 
ATOM   1947  O O   . LEU A 1 286 ? 93.198  91.061  90.572  1.00 19.77 ? 265  LEU A O   1 
ATOM   1948  C CB  . LEU A 1 286 ? 95.088  88.379  90.084  1.00 19.77 ? 265  LEU A CB  1 
ATOM   1949  C CG  . LEU A 1 286 ? 96.518  87.916  90.367  1.00 19.77 ? 265  LEU A CG  1 
ATOM   1950  C CD1 . LEU A 1 286 ? 96.530  86.511  90.914  1.00 19.77 ? 265  LEU A CD1 1 
ATOM   1951  C CD2 . LEU A 1 286 ? 97.382  88.012  89.117  1.00 19.77 ? 265  LEU A CD2 1 
ATOM   1952  N N   . GLY A 1 287 ? 92.806  89.965  88.642  1.00 19.31 ? 266  GLY A N   1 
ATOM   1953  C CA  . GLY A 1 287 ? 91.464  90.503  88.514  1.00 19.31 ? 266  GLY A CA  1 
ATOM   1954  C C   . GLY A 1 287 ? 90.555  90.033  89.635  1.00 19.31 ? 266  GLY A C   1 
ATOM   1955  O O   . GLY A 1 287 ? 90.660  88.905  90.118  1.00 19.31 ? 266  GLY A O   1 
ATOM   1956  N N   . GLY A 1 288 ? 89.644  90.917  90.047  1.00 17.58 ? 267  GLY A N   1 
ATOM   1957  C CA  . GLY A 1 288 ? 88.686  90.593  91.077  1.00 17.58 ? 267  GLY A CA  1 
ATOM   1958  C C   . GLY A 1 288 ? 87.270  90.919  90.641  1.00 17.58 ? 267  GLY A C   1 
ATOM   1959  O O   . GLY A 1 288 ? 87.038  91.770  89.785  1.00 17.58 ? 267  GLY A O   1 
ATOM   1960  N N   . LYS A 1 289 ? 86.318  90.218  91.252  1.00 13.35 ? 268  LYS A N   1 
ATOM   1961  C CA  . LYS A 1 289 ? 84.896  90.468  91.022  1.00 13.35 ? 268  LYS A CA  1 
ATOM   1962  C C   . LYS A 1 289 ? 84.442  91.470  92.075  1.00 13.35 ? 268  LYS A C   1 
ATOM   1963  O O   . LYS A 1 289 ? 84.152  91.107  93.216  1.00 13.35 ? 268  LYS A O   1 
ATOM   1964  C CB  . LYS A 1 289 ? 84.099  89.170  91.085  1.00 13.35 ? 268  LYS A CB  1 
ATOM   1965  C CG  . LYS A 1 289 ? 82.590  89.350  91.128  1.00 13.35 ? 268  LYS A CG  1 
ATOM   1966  C CD  . LYS A 1 289 ? 82.090  90.133  89.934  1.00 13.35 ? 268  LYS A CD  1 
ATOM   1967  C CE  . LYS A 1 289 ? 82.290  89.365  88.644  1.00 13.35 ? 268  LYS A CE  1 
ATOM   1968  N NZ  . LYS A 1 289 ? 81.272  88.307  88.473  1.00 13.35 ? 268  LYS A NZ  1 
ATOM   1969  N N   . SER A 1 290 ? 84.377  92.740  91.685  1.00 7.89  ? 269  SER A N   1 
ATOM   1970  C CA  . SER A 1 290 ? 84.275  93.833  92.636  1.00 7.89  ? 269  SER A CA  1 
ATOM   1971  C C   . SER A 1 290 ? 82.819  94.146  92.919  1.00 7.89  ? 269  SER A C   1 
ATOM   1972  O O   . SER A 1 290 ? 82.078  94.470  91.982  1.00 7.89  ? 269  SER A O   1 
ATOM   1973  C CB  . SER A 1 290 ? 84.975  95.063  92.083  1.00 7.89  ? 269  SER A CB  1 
ATOM   1974  O OG  . SER A 1 290 ? 86.360  94.820  91.926  1.00 7.89  ? 269  SER A OG  1 
ATOM   1975  N N   . PRO A 1 291 ? 82.365  94.073  94.163  1.00 5.74  ? 270  PRO A N   1 
ATOM   1976  C CA  . PRO A 1 291 ? 80.990  94.469  94.464  1.00 5.74  ? 270  PRO A CA  1 
ATOM   1977  C C   . PRO A 1 291 ? 80.824  95.977  94.394  1.00 5.74  ? 270  PRO A C   1 
ATOM   1978  O O   . PRO A 1 291 ? 81.781  96.747  94.468  1.00 5.74  ? 270  PRO A O   1 
ATOM   1979  C CB  . PRO A 1 291 ? 80.775  93.951  95.886  1.00 5.74  ? 270  PRO A CB  1 
ATOM   1980  C CG  . PRO A 1 291 ? 82.123  93.947  96.476  1.00 5.74  ? 270  PRO A CG  1 
ATOM   1981  C CD  . PRO A 1 291 ? 83.084  93.631  95.367  1.00 5.74  ? 270  PRO A CD  1 
ATOM   1982  N N   . ASN A 1 292 ? 79.573  96.395  94.237  1.00 4.54  ? 271  ASN A N   1 
ATOM   1983  C CA  . ASN A 1 292 ? 79.216  97.813  94.190  1.00 4.54  ? 271  ASN A CA  1 
ATOM   1984  C C   . ASN A 1 292 ? 77.885  97.936  94.925  1.00 4.54  ? 271  ASN A C   1 
ATOM   1985  O O   . ASN A 1 292 ? 76.820  97.781  94.328  1.00 4.54  ? 271  ASN A O   1 
ATOM   1986  C CB  . ASN A 1 292 ? 79.136  98.306  92.754  1.00 4.54  ? 271  ASN A CB  1 
ATOM   1987  C CG  . ASN A 1 292 ? 79.051  99.810  92.654  1.00 4.54  ? 271  ASN A CG  1 
ATOM   1988  O OD1 . ASN A 1 292 ? 78.784  100.496 93.635  1.00 4.54  ? 271  ASN A OD1 1 
ATOM   1989  N ND2 . ASN A 1 292 ? 79.284  100.333 91.459  1.00 4.54  ? 271  ASN A ND2 1 
ATOM   1990  N N   . ILE A 1 293 ? 77.957  98.214  96.215  1.00 3.19  ? 272  ILE A N   1 
ATOM   1991  C CA  . ILE A 1 293 ? 76.779  98.215  97.074  1.00 3.19  ? 272  ILE A CA  1 
ATOM   1992  C C   . ILE A 1 293 ? 76.079  99.563  96.982  1.00 3.19  ? 272  ILE A C   1 
ATOM   1993  O O   . ILE A 1 293 ? 76.721  100.616 97.025  1.00 3.19  ? 272  ILE A O   1 
ATOM   1994  C CB  . ILE A 1 293 ? 77.168  97.886  98.525  1.00 3.19  ? 272  ILE A CB  1 
ATOM   1995  C CG1 . ILE A 1 293 ? 77.743  96.473  98.638  1.00 3.19  ? 272  ILE A CG1 1 
ATOM   1996  C CG2 . ILE A 1 293 ? 75.980  98.011  99.427  1.00 3.19  ? 272  ILE A CG2 1 
ATOM   1997  C CD1 . ILE A 1 293 ? 79.236  96.391  98.488  1.00 3.19  ? 272  ILE A CD1 1 
ATOM   1998  N N   . PHE A 1 294 ? 74.755  99.534  96.846  1.00 4.65  ? 273  PHE A N   1 
ATOM   1999  C CA  . PHE A 1 294 ? 73.925  100.735 96.795  1.00 4.65  ? 273  PHE A CA  1 
ATOM   2000  C C   . PHE A 1 294 ? 72.890  100.654 97.906  1.00 4.65  ? 273  PHE A C   1 
ATOM   2001  O O   . PHE A 1 294 ? 71.935  99.879  97.812  1.00 4.65  ? 273  PHE A O   1 
ATOM   2002  C CB  . PHE A 1 294 ? 73.236  100.874 95.442  1.00 4.65  ? 273  PHE A CB  1 
ATOM   2003  C CG  . PHE A 1 294 ? 74.159  101.194 94.327  1.00 4.65  ? 273  PHE A CG  1 
ATOM   2004  C CD1 . PHE A 1 294 ? 74.764  100.189 93.609  1.00 4.65  ? 273  PHE A CD1 1 
ATOM   2005  C CD2 . PHE A 1 294 ? 74.418  102.500 93.985  1.00 4.65  ? 273  PHE A CD2 1 
ATOM   2006  C CE1 . PHE A 1 294 ? 75.615  100.480 92.576  1.00 4.65  ? 273  PHE A CE1 1 
ATOM   2007  C CE2 . PHE A 1 294 ? 75.269  102.793 92.953  1.00 4.65  ? 273  PHE A CE2 1 
ATOM   2008  C CZ  . PHE A 1 294 ? 75.868  101.781 92.248  1.00 4.65  ? 273  PHE A CZ  1 
ATOM   2009  N N   . PHE A 1 295 ? 73.064  101.459 98.944  1.00 6.84  ? 274  PHE A N   1 
ATOM   2010  C CA  . PHE A 1 295 ? 72.121  101.432 100.047 1.00 6.84  ? 274  PHE A CA  1 
ATOM   2011  C C   . PHE A 1 295 ? 70.864  102.225 99.708  1.00 6.84  ? 274  PHE A C   1 
ATOM   2012  O O   . PHE A 1 295 ? 70.851  103.072 98.813  1.00 6.84  ? 274  PHE A O   1 
ATOM   2013  C CB  . PHE A 1 295 ? 72.767  101.969 101.318 1.00 6.84  ? 274  PHE A CB  1 
ATOM   2014  C CG  . PHE A 1 295 ? 73.640  100.969 102.008 1.00 6.84  ? 274  PHE A CG  1 
ATOM   2015  C CD1 . PHE A 1 295 ? 74.946  100.778 101.606 1.00 6.84  ? 274  PHE A CD1 1 
ATOM   2016  C CD2 . PHE A 1 295 ? 73.144  100.196 103.036 1.00 6.84  ? 274  PHE A CD2 1 
ATOM   2017  C CE1 . PHE A 1 295 ? 75.742  99.854  102.234 1.00 6.84  ? 274  PHE A CE1 1 
ATOM   2018  C CE2 . PHE A 1 295 ? 73.938  99.270  103.662 1.00 6.84  ? 274  PHE A CE2 1 
ATOM   2019  C CZ  . PHE A 1 295 ? 75.237  99.098  103.259 1.00 6.84  ? 274  PHE A CZ  1 
ATOM   2020  N N   . ALA A 1 296 ? 69.791  101.935 100.445 1.00 11.99 ? 275  ALA A N   1 
ATOM   2021  C CA  . ALA A 1 296 ? 68.492  102.545 100.186 1.00 11.99 ? 275  ALA A CA  1 
ATOM   2022  C C   . ALA A 1 296 ? 68.452  104.027 100.514 1.00 11.99 ? 275  ALA A C   1 
ATOM   2023  O O   . ALA A 1 296 ? 67.394  104.646 100.362 1.00 11.99 ? 275  ALA A O   1 
ATOM   2024  C CB  . ALA A 1 296 ? 67.403  101.817 100.971 1.00 11.99 ? 275  ALA A CB  1 
ATOM   2025  N N   . ASP A 1 297 ? 69.560  104.608 100.963 1.00 13.88 ? 276  ASP A N   1 
ATOM   2026  C CA  . ASP A 1 297 ? 69.613  106.036 101.219 1.00 13.88 ? 276  ASP A CA  1 
ATOM   2027  C C   . ASP A 1 297 ? 70.048  106.841 100.004 1.00 13.88 ? 276  ASP A C   1 
ATOM   2028  O O   . ASP A 1 297 ? 69.837  108.058 99.981  1.00 13.88 ? 276  ASP A O   1 
ATOM   2029  C CB  . ASP A 1 297 ? 70.556  106.323 102.388 1.00 13.88 ? 276  ASP A CB  1 
ATOM   2030  C CG  . ASP A 1 297 ? 70.039  107.418 103.293 1.00 13.88 ? 276  ASP A CG  1 
ATOM   2031  O OD1 . ASP A 1 297 ? 69.131  108.157 102.864 1.00 13.88 ? 276  ASP A OD1 1 
ATOM   2032  O OD2 . ASP A 1 297 ? 70.533  107.534 104.434 1.00 13.88 ? 276  ASP A OD2 1 
ATOM   2033  N N   . VAL A 1 298 ? 70.640  106.200 98.994  1.00 11.03 ? 277  VAL A N   1 
ATOM   2034  C CA  . VAL A 1 298 ? 71.101  106.946 97.828  1.00 11.03 ? 277  VAL A CA  1 
ATOM   2035  C C   . VAL A 1 298 ? 69.931  107.576 97.091  1.00 11.03 ? 277  VAL A C   1 
ATOM   2036  O O   . VAL A 1 298 ? 70.095  108.587 96.400  1.00 11.03 ? 277  VAL A O   1 
ATOM   2037  C CB  . VAL A 1 298 ? 71.932  106.042 96.894  1.00 11.03 ? 277  VAL A CB  1 
ATOM   2038  C CG1 . VAL A 1 298 ? 73.048  105.367 97.662  1.00 11.03 ? 277  VAL A CG1 1 
ATOM   2039  C CG2 . VAL A 1 298 ? 71.053  105.018 96.210  1.00 11.03 ? 277  VAL A CG2 1 
ATOM   2040  N N   . ALA A 1 299 ? 68.737  107.004 97.225  1.00 15.35 ? 278  ALA A N   1 
ATOM   2041  C CA  . ALA A 1 299 ? 67.561  107.481 96.516  1.00 15.35 ? 278  ALA A CA  1 
ATOM   2042  C C   . ALA A 1 299 ? 66.567  108.188 97.423  1.00 15.35 ? 278  ALA A C   1 
ATOM   2043  O O   . ALA A 1 299 ? 65.380  108.247 97.091  1.00 15.35 ? 278  ALA A O   1 
ATOM   2044  C CB  . ALA A 1 299 ? 66.870  106.321 95.804  1.00 15.35 ? 278  ALA A CB  1 
ATOM   2045  N N   . ARG A 1 300 ? 67.015  108.711 98.564  1.00 15.70 ? 279  ARG A N   1 
ATOM   2046  C CA  . ARG A 1 300 ? 66.105  109.389 99.479  1.00 15.70 ? 279  ARG A CA  1 
ATOM   2047  C C   . ARG A 1 300 ? 65.482  110.618 98.825  1.00 15.70 ? 279  ARG A C   1 
ATOM   2048  O O   . ARG A 1 300 ? 64.260  110.706 98.667  1.00 15.70 ? 279  ARG A O   1 
ATOM   2049  C CB  . ARG A 1 300 ? 66.845  109.769 100.762 1.00 15.70 ? 279  ARG A CB  1 
ATOM   2050  C CG  . ARG A 1 300 ? 66.006  110.567 101.742 1.00 15.70 ? 279  ARG A CG  1 
ATOM   2051  C CD  . ARG A 1 300 ? 66.867  111.371 102.701 1.00 15.70 ? 279  ARG A CD  1 
ATOM   2052  N NE  . ARG A 1 300 ? 67.510  110.527 103.704 1.00 15.70 ? 279  ARG A NE  1 
ATOM   2053  C CZ  . ARG A 1 300 ? 68.465  110.942 104.529 1.00 15.70 ? 279  ARG A CZ  1 
ATOM   2054  N NH1 . ARG A 1 300 ? 68.893  112.195 104.475 1.00 15.70 ? 279  ARG A NH1 1 
ATOM   2055  N NH2 . ARG A 1 300 ? 68.993  110.105 105.410 1.00 15.70 ? 279  ARG A NH2 1 
ATOM   2056  N N   . GLU A 1 301 ? 66.315  111.572 98.425  1.00 18.05 ? 280  GLU A N   1 
ATOM   2057  C CA  . GLU A 1 301 ? 65.856  112.845 97.891  1.00 18.05 ? 280  GLU A CA  1 
ATOM   2058  C C   . GLU A 1 301 ? 66.002  112.954 96.381  1.00 18.05 ? 280  GLU A C   1 
ATOM   2059  O O   . GLU A 1 301 ? 65.833  114.052 95.847  1.00 18.05 ? 280  GLU A O   1 
ATOM   2060  C CB  . GLU A 1 301 ? 66.630  113.988 98.554  1.00 18.05 ? 280  GLU A CB  1 
ATOM   2061  C CG  . GLU A 1 301 ? 66.694  113.894 100.069 1.00 18.05 ? 280  GLU A CG  1 
ATOM   2062  C CD  . GLU A 1 301 ? 66.643  115.249 100.742 1.00 18.05 ? 280  GLU A CD  1 
ATOM   2063  O OE1 . GLU A 1 301 ? 66.491  115.292 101.980 1.00 18.05 ? 280  GLU A OE1 1 
ATOM   2064  O OE2 . GLU A 1 301 ? 66.761  116.270 100.032 1.00 18.05 ? 280  GLU A OE2 1 
ATOM   2065  N N   . ASP A 1 302 ? 66.422  111.873 95.714  1.00 17.43 ? 281  ASP A N   1 
ATOM   2066  C CA  . ASP A 1 302 ? 66.703  111.723 94.280  1.00 17.43 ? 281  ASP A CA  1 
ATOM   2067  C C   . ASP A 1 302 ? 67.386  112.968 93.722  1.00 17.43 ? 281  ASP A C   1 
ATOM   2068  O O   . ASP A 1 302 ? 67.204  113.324 92.554  1.00 17.43 ? 281  ASP A O   1 
ATOM   2069  C CB  . ASP A 1 302 ? 65.464  111.336 93.443  1.00 17.43 ? 281  ASP A CB  1 
ATOM   2070  C CG  . ASP A 1 302 ? 64.407  112.426 93.323  1.00 17.43 ? 281  ASP A CG  1 
ATOM   2071  O OD1 . ASP A 1 302 ? 64.533  113.523 93.880  1.00 17.43 ? 281  ASP A OD1 1 
ATOM   2072  O OD2 . ASP A 1 302 ? 63.414  112.163 92.614  1.00 17.43 ? 281  ASP A OD2 1 
ATOM   2073  N N   . ASP A 1 303 ? 68.193  113.612 94.556  1.00 15.18 ? 282  ASP A N   1 
ATOM   2074  C CA  . ASP A 1 303 ? 68.902  114.832 94.202  1.00 15.18 ? 282  ASP A CA  1 
ATOM   2075  C C   . ASP A 1 303 ? 70.152  114.474 93.406  1.00 15.18 ? 282  ASP A C   1 
ATOM   2076  O O   . ASP A 1 303 ? 70.306  113.349 92.924  1.00 15.18 ? 282  ASP A O   1 
ATOM   2077  C CB  . ASP A 1 303 ? 69.186  115.639 95.466  1.00 15.18 ? 282  ASP A CB  1 
ATOM   2078  C CG  . ASP A 1 303 ? 69.926  114.838 96.516  1.00 15.18 ? 282  ASP A CG  1 
ATOM   2079  O OD1 . ASP A 1 303 ? 70.177  113.640 96.281  1.00 15.18 ? 282  ASP A OD1 1 
ATOM   2080  O OD2 . ASP A 1 303 ? 70.232  115.400 97.588  1.00 15.18 ? 282  ASP A OD2 1 
ATOM   2081  N N   . ASP A 1 304 ? 71.061  115.438 93.243  1.00 13.04 ? 283  ASP A N   1 
ATOM   2082  C CA  . ASP A 1 304 ? 72.270  115.201 92.461  1.00 13.04 ? 283  ASP A CA  1 
ATOM   2083  C C   . ASP A 1 304 ? 73.081  114.026 92.987  1.00 13.04 ? 283  ASP A C   1 
ATOM   2084  O O   . ASP A 1 304 ? 73.838  113.420 92.221  1.00 13.04 ? 283  ASP A O   1 
ATOM   2085  C CB  . ASP A 1 304 ? 73.133  116.459 92.442  1.00 13.04 ? 283  ASP A CB  1 
ATOM   2086  C CG  . ASP A 1 304 ? 73.220  117.124 93.801  1.00 13.04 ? 283  ASP A CG  1 
ATOM   2087  O OD1 . ASP A 1 304 ? 73.066  116.418 94.821  1.00 13.04 ? 283  ASP A OD1 1 
ATOM   2088  O OD2 . ASP A 1 304 ? 73.439  118.353 93.851  1.00 13.04 ? 283  ASP A OD2 1 
ATOM   2089  N N   . PHE A 1 305 ? 72.945  113.687 94.271  1.00 9.70  ? 284  PHE A N   1 
ATOM   2090  C CA  . PHE A 1 305 ? 73.622  112.499 94.776  1.00 9.70  ? 284  PHE A CA  1 
ATOM   2091  C C   . PHE A 1 305 ? 73.048  111.233 94.159  1.00 9.70  ? 284  PHE A C   1 
ATOM   2092  O O   . PHE A 1 305 ? 73.782  110.272 93.911  1.00 9.70  ? 284  PHE A O   1 
ATOM   2093  C CB  . PHE A 1 305 ? 73.531  112.422 96.294  1.00 9.70  ? 284  PHE A CB  1 
ATOM   2094  C CG  . PHE A 1 305 ? 74.136  111.174 96.859  1.00 9.70  ? 284  PHE A CG  1 
ATOM   2095  C CD1 . PHE A 1 305 ? 75.469  110.887 96.652  1.00 9.70  ? 284  PHE A CD1 1 
ATOM   2096  C CD2 . PHE A 1 305 ? 73.371  110.276 97.571  1.00 9.70  ? 284  PHE A CD2 1 
ATOM   2097  C CE1 . PHE A 1 305 ? 76.028  109.743 97.159  1.00 9.70  ? 284  PHE A CE1 1 
ATOM   2098  C CE2 . PHE A 1 305 ? 73.930  109.131 98.078  1.00 9.70  ? 284  PHE A CE2 1 
ATOM   2099  C CZ  . PHE A 1 305 ? 75.260  108.866 97.871  1.00 9.70  ? 284  PHE A CZ  1 
ATOM   2100  N N   . PHE A 1 306 ? 71.738  111.202 93.914  1.00 11.51 ? 285  PHE A N   1 
ATOM   2101  C CA  . PHE A 1 306 ? 71.156  110.049 93.239  1.00 11.51 ? 285  PHE A CA  1 
ATOM   2102  C C   . PHE A 1 306 ? 71.634  109.957 91.797  1.00 11.51 ? 285  PHE A C   1 
ATOM   2103  O O   . PHE A 1 306 ? 71.868  108.858 91.282  1.00 11.51 ? 285  PHE A O   1 
ATOM   2104  C CB  . PHE A 1 306 ? 69.638  110.113 93.304  1.00 11.51 ? 285  PHE A CB  1 
ATOM   2105  C CG  . PHE A 1 306 ? 68.966  108.824 92.958  1.00 11.51 ? 285  PHE A CG  1 
ATOM   2106  C CD1 . PHE A 1 306 ? 69.480  107.623 93.402  1.00 11.51 ? 285  PHE A CD1 1 
ATOM   2107  C CD2 . PHE A 1 306 ? 67.807  108.812 92.206  1.00 11.51 ? 285  PHE A CD2 1 
ATOM   2108  C CE1 . PHE A 1 306 ? 68.864  106.434 93.082  1.00 11.51 ? 285  PHE A CE1 1 
ATOM   2109  C CE2 . PHE A 1 306 ? 67.183  107.628 91.892  1.00 11.51 ? 285  PHE A CE2 1 
ATOM   2110  C CZ  . PHE A 1 306 ? 67.711  106.438 92.331  1.00 11.51 ? 285  PHE A CZ  1 
ATOM   2111  N N   . ASP A 1 307 ? 71.792  111.099 91.131  1.00 13.23 ? 286  ASP A N   1 
ATOM   2112  C CA  . ASP A 1 307 ? 72.398  111.086 89.808  1.00 13.23 ? 286  ASP A CA  1 
ATOM   2113  C C   . ASP A 1 307 ? 73.823  110.561 89.869  1.00 13.23 ? 286  ASP A C   1 
ATOM   2114  O O   . ASP A 1 307 ? 74.259  109.830 88.976  1.00 13.23 ? 286  ASP A O   1 
ATOM   2115  C CB  . ASP A 1 307 ? 72.366  112.484 89.201  1.00 13.23 ? 286  ASP A CB  1 
ATOM   2116  C CG  . ASP A 1 307 ? 70.997  112.860 88.700  1.00 13.23 ? 286  ASP A CG  1 
ATOM   2117  O OD1 . ASP A 1 307 ? 70.196  113.378 89.505  1.00 13.23 ? 286  ASP A OD1 1 
ATOM   2118  O OD2 . ASP A 1 307 ? 70.719  112.633 87.504  1.00 13.23 ? 286  ASP A OD2 1 
ATOM   2119  N N   . LYS A 1 308 ? 74.563  110.921 90.919  1.00 8.72  ? 287  LYS A N   1 
ATOM   2120  C CA  . LYS A 1 308 ? 75.916  110.399 91.080  1.00 8.72  ? 287  LYS A CA  1 
ATOM   2121  C C   . LYS A 1 308 ? 75.903  108.891 91.296  1.00 8.72  ? 287  LYS A C   1 
ATOM   2122  O O   . LYS A 1 308 ? 76.760  108.173 90.772  1.00 8.72  ? 287  LYS A O   1 
ATOM   2123  C CB  . LYS A 1 308 ? 76.616  111.098 92.243  1.00 8.72  ? 287  LYS A CB  1 
ATOM   2124  C CG  . LYS A 1 308 ? 78.124  110.997 92.184  1.00 8.72  ? 287  LYS A CG  1 
ATOM   2125  C CD  . LYS A 1 308 ? 78.758  111.356 93.503  1.00 8.72  ? 287  LYS A CD  1 
ATOM   2126  C CE  . LYS A 1 308 ? 80.264  111.362 93.380  1.00 8.72  ? 287  LYS A CE  1 
ATOM   2127  N NZ  . LYS A 1 308 ? 80.908  112.023 94.540  1.00 8.72  ? 287  LYS A NZ  1 
ATOM   2128  N N   . ALA A 1 309 ? 74.943  108.394 92.076  1.00 7.71  ? 288  ALA A N   1 
ATOM   2129  C CA  . ALA A 1 309 ? 74.857  106.958 92.317  1.00 7.71  ? 288  ALA A CA  1 
ATOM   2130  C C   . ALA A 1 309 ? 74.501  106.202 91.045  1.00 7.71  ? 288  ALA A C   1 
ATOM   2131  O O   . ALA A 1 309 ? 75.035  105.117 90.794  1.00 7.71  ? 288  ALA A O   1 
ATOM   2132  C CB  . ALA A 1 309 ? 73.843  106.667 93.419  1.00 7.71  ? 288  ALA A CB  1 
ATOM   2133  N N   . LEU A 1 310 ? 73.598  106.750 90.232  1.00 9.81  ? 289  LEU A N   1 
ATOM   2134  C CA  . LEU A 1 310 ? 73.285  106.122 88.951  1.00 9.81  ? 289  LEU A CA  1 
ATOM   2135  C C   . LEU A 1 310 ? 74.480  106.175 88.006  1.00 9.81  ? 289  LEU A C   1 
ATOM   2136  O O   . LEU A 1 310 ? 74.728  105.229 87.249  1.00 9.81  ? 289  LEU A O   1 
ATOM   2137  C CB  . LEU A 1 310 ? 72.064  106.790 88.325  1.00 9.81  ? 289  LEU A CB  1 
ATOM   2138  C CG  . LEU A 1 310 ? 70.781  106.704 89.149  1.00 9.81  ? 289  LEU A CG  1 
ATOM   2139  C CD1 . LEU A 1 310 ? 69.729  107.646 88.612  1.00 9.81  ? 289  LEU A CD1 1 
ATOM   2140  C CD2 . LEU A 1 310 ? 70.263  105.287 89.172  1.00 9.81  ? 289  LEU A CD2 1 
ATOM   2141  N N   . GLU A 1 311 ? 75.226  107.280 88.036  1.00 13.46 ? 290  GLU A N   1 
ATOM   2142  C CA  . GLU A 1 311 ? 76.510  107.358 87.350  1.00 13.46 ? 290  GLU A CA  1 
ATOM   2143  C C   . GLU A 1 311 ? 77.412  106.202 87.761  1.00 13.46 ? 290  GLU A C   1 
ATOM   2144  O O   . GLU A 1 311 ? 77.993  105.511 86.918  1.00 13.46 ? 290  GLU A O   1 
ATOM   2145  C CB  . GLU A 1 311 ? 77.173  108.694 87.687  1.00 13.46 ? 290  GLU A CB  1 
ATOM   2146  C CG  . GLU A 1 311 ? 78.509  108.953 87.025  1.00 13.46 ? 290  GLU A CG  1 
ATOM   2147  C CD  . GLU A 1 311 ? 78.364  109.329 85.572  1.00 13.46 ? 290  GLU A CD  1 
ATOM   2148  O OE1 . GLU A 1 311 ? 78.615  110.505 85.235  1.00 13.46 ? 290  GLU A OE1 1 
ATOM   2149  O OE2 . GLU A 1 311 ? 77.979  108.461 84.770  1.00 13.46 ? 290  GLU A OE2 1 
ATOM   2150  N N   . GLY A 1 312 ? 77.530  105.978 89.069  1.00 8.64  ? 291  GLY A N   1 
ATOM   2151  C CA  . GLY A 1 312 ? 78.410  104.932 89.560  1.00 8.64  ? 291  GLY A CA  1 
ATOM   2152  C C   . GLY A 1 312 ? 77.942  103.542 89.183  1.00 8.64  ? 291  GLY A C   1 
ATOM   2153  O O   . GLY A 1 312 ? 78.756  102.656 88.914  1.00 8.64  ? 291  GLY A O   1 
ATOM   2154  N N   . PHE A 1 313 ? 76.629  103.324 89.180  1.00 7.62  ? 292  PHE A N   1 
ATOM   2155  C CA  . PHE A 1 313 ? 76.101  102.053 88.701  1.00 7.62  ? 292  PHE A CA  1 
ATOM   2156  C C   . PHE A 1 313 ? 76.462  101.834 87.241  1.00 7.62  ? 292  PHE A C   1 
ATOM   2157  O O   . PHE A 1 313 ? 76.927  100.756 86.861  1.00 7.62  ? 292  PHE A O   1 
ATOM   2158  C CB  . PHE A 1 313 ? 74.586  101.996 88.877  1.00 7.62  ? 292  PHE A CB  1 
ATOM   2159  C CG  . PHE A 1 313 ? 73.942  100.883 88.112  1.00 7.62  ? 292  PHE A CG  1 
ATOM   2160  C CD1 . PHE A 1 313 ? 74.015  99.584  88.571  1.00 7.62  ? 292  PHE A CD1 1 
ATOM   2161  C CD2 . PHE A 1 313 ? 73.295  101.126 86.920  1.00 7.62  ? 292  PHE A CD2 1 
ATOM   2162  C CE1 . PHE A 1 313 ? 73.439  98.555  87.867  1.00 7.62  ? 292  PHE A CE1 1 
ATOM   2163  C CE2 . PHE A 1 313 ? 72.720  100.097 86.213  1.00 7.62  ? 292  PHE A CE2 1 
ATOM   2164  C CZ  . PHE A 1 313 ? 72.792  98.811  86.689  1.00 7.62  ? 292  PHE A CZ  1 
ATOM   2165  N N   . THR A 1 314 ? 76.252  102.852 86.404  1.00 9.57  ? 293  THR A N   1 
ATOM   2166  C CA  . THR A 1 314 ? 76.605  102.750 84.994  1.00 9.57  ? 293  THR A CA  1 
ATOM   2167  C C   . THR A 1 314 ? 78.105  102.661 84.773  1.00 9.57  ? 293  THR A C   1 
ATOM   2168  O O   . THR A 1 314 ? 78.531  102.308 83.670  1.00 9.57  ? 293  THR A O   1 
ATOM   2169  C CB  . THR A 1 314 ? 76.055  103.945 84.220  1.00 9.57  ? 293  THR A CB  1 
ATOM   2170  O OG1 . THR A 1 314 ? 76.550  105.156 84.802  1.00 9.57  ? 293  THR A OG1 1 
ATOM   2171  C CG2 . THR A 1 314 ? 74.545  103.958 84.273  1.00 9.57  ? 293  THR A CG2 1 
ATOM   2172  N N   . MET A 1 315 ? 78.902  102.972 85.781  1.00 10.21 ? 294  MET A N   1 
ATOM   2173  C CA  . MET A 1 315 ? 80.353  102.874 85.648  1.00 10.21 ? 294  MET A CA  1 
ATOM   2174  C C   . MET A 1 315 ? 80.844  101.457 85.451  1.00 10.21 ? 294  MET A C   1 
ATOM   2175  O O   . MET A 1 315 ? 82.063  101.294 85.396  1.00 10.21 ? 294  MET A O   1 
ATOM   2176  C CB  . MET A 1 315 ? 81.036  103.486 86.871  1.00 10.21 ? 294  MET A CB  1 
ATOM   2177  C CG  . MET A 1 315 ? 81.091  105.001 86.845  1.00 10.21 ? 294  MET A CG  1 
ATOM   2178  S SD  . MET A 1 315 ? 82.024  105.710 88.207  1.00 10.21 ? 294  MET A SD  1 
ATOM   2179  C CE  . MET A 1 315 ? 81.922  107.451 87.800  1.00 10.21 ? 294  MET A CE  1 
ATOM   2180  N N   . PHE A 1 316 ? 79.993  100.433 85.357  1.00 8.15  ? 295  PHE A N   1 
ATOM   2181  C CA  . PHE A 1 316 ? 80.468  99.101  85.007  1.00 8.15  ? 295  PHE A CA  1 
ATOM   2182  C C   . PHE A 1 316 ? 80.927  99.020  83.561  1.00 8.15  ? 295  PHE A C   1 
ATOM   2183  O O   . PHE A 1 316 ? 81.694  98.117  83.216  1.00 8.15  ? 295  PHE A O   1 
ATOM   2184  C CB  . PHE A 1 316 ? 79.377  98.056  85.264  1.00 8.15  ? 295  PHE A CB  1 
ATOM   2185  C CG  . PHE A 1 316 ? 78.244  98.091  84.270  1.00 8.15  ? 295  PHE A CG  1 
ATOM   2186  C CD1 . PHE A 1 316 ? 78.314  97.385  83.084  1.00 8.15  ? 295  PHE A CD1 1 
ATOM   2187  C CD2 . PHE A 1 316 ? 77.100  98.819  84.533  1.00 8.15  ? 295  PHE A CD2 1 
ATOM   2188  C CE1 . PHE A 1 316 ? 77.278  97.420  82.181  1.00 8.15  ? 295  PHE A CE1 1 
ATOM   2189  C CE2 . PHE A 1 316 ? 76.062  98.852  83.631  1.00 8.15  ? 295  PHE A CE2 1 
ATOM   2190  C CZ  . PHE A 1 316 ? 76.153  98.150  82.456  1.00 8.15  ? 295  PHE A CZ  1 
ATOM   2191  N N   . ALA A 1 317 ? 80.467  99.931  82.710  1.00 9.09  ? 296  ALA A N   1 
ATOM   2192  C CA  . ALA A 1 317 ? 80.808  99.929  81.297  1.00 9.09  ? 296  ALA A CA  1 
ATOM   2193  C C   . ALA A 1 317 ? 82.005  100.810 80.989  1.00 9.09  ? 296  ALA A C   1 
ATOM   2194  O O   . ALA A 1 317 ? 82.320  101.022 79.815  1.00 9.09  ? 296  ALA A O   1 
ATOM   2195  C CB  . ALA A 1 317 ? 79.605  100.369 80.465  1.00 9.09  ? 296  ALA A CB  1 
ATOM   2196  N N   . LEU A 1 318 ? 82.665  101.345 82.012  1.00 9.57  ? 297  LEU A N   1 
ATOM   2197  C CA  . LEU A 1 318 ? 83.901  102.077 81.796  1.00 9.57  ? 297  LEU A CA  1 
ATOM   2198  C C   . LEU A 1 318 ? 84.989  101.128 81.316  1.00 9.57  ? 297  LEU A C   1 
ATOM   2199  O O   . LEU A 1 318 ? 85.129  100.013 81.824  1.00 9.57  ? 297  LEU A O   1 
ATOM   2200  C CB  . LEU A 1 318 ? 84.335  102.773 83.080  1.00 9.57  ? 297  LEU A CB  1 
ATOM   2201  C CG  . LEU A 1 318 ? 85.553  103.684 82.962  1.00 9.57  ? 297  LEU A CG  1 
ATOM   2202  C CD1 . LEU A 1 318 ? 85.241  104.877 82.078  1.00 9.57  ? 297  LEU A CD1 1 
ATOM   2203  C CD2 . LEU A 1 318 ? 85.997  104.138 84.332  1.00 9.57  ? 297  LEU A CD2 1 
ATOM   2204  N N   . ASN A 1 319 ? 85.759  101.572 80.325  1.00 9.81  ? 298  ASN A N   1 
ATOM   2205  C CA  . ASN A 1 319 ? 86.761  100.742 79.665  1.00 9.81  ? 298  ASN A CA  1 
ATOM   2206  C C   . ASN A 1 319 ? 86.149  99.476  79.071  1.00 9.81  ? 298  ASN A C   1 
ATOM   2207  O O   . ASN A 1 319 ? 86.836  98.462  78.917  1.00 9.81  ? 298  ASN A O   1 
ATOM   2208  C CB  . ASN A 1 319 ? 87.905  100.386 80.622  1.00 9.81  ? 298  ASN A CB  1 
ATOM   2209  C CG  . ASN A 1 319 ? 89.174  99.995  79.897  1.00 9.81  ? 298  ASN A CG  1 
ATOM   2210  O OD1 . ASN A 1 319 ? 89.247  100.056 78.672  1.00 9.81  ? 298  ASN A OD1 1 
ATOM   2211  N ND2 . ASN A 1 319 ? 90.179  99.580  80.652  1.00 9.81  ? 298  ASN A ND2 1 
ATOM   2212  N N   . GLN A 1 320 ? 84.861  99.532  78.722  1.00 9.57  ? 299  GLN A N   1 
ATOM   2213  C CA  . GLN A 1 320 ? 84.110  98.372  78.246  1.00 9.57  ? 299  GLN A CA  1 
ATOM   2214  C C   . GLN A 1 320 ? 84.200  97.219  79.240  1.00 9.57  ? 299  GLN A C   1 
ATOM   2215  O O   . GLN A 1 320 ? 84.417  96.066  78.872  1.00 9.57  ? 299  GLN A O   1 
ATOM   2216  C CB  . GLN A 1 320 ? 84.585  97.937  76.862  1.00 9.57  ? 299  GLN A CB  1 
ATOM   2217  C CG  . GLN A 1 320 ? 84.771  99.078  75.897  1.00 9.57  ? 299  GLN A CG  1 
ATOM   2218  C CD  . GLN A 1 320 ? 86.220  99.488  75.750  1.00 9.57  ? 299  GLN A CD  1 
ATOM   2219  O OE1 . GLN A 1 320 ? 87.135  98.704  76.007  1.00 9.57  ? 299  GLN A OE1 1 
ATOM   2220  N NE2 . GLN A 1 320 ? 86.437  100.720 75.326  1.00 9.57  ? 299  GLN A NE2 1 
ATOM   2221  N N   . GLY A 1 321 ? 84.053  97.548  80.522  1.00 9.94  ? 300  GLY A N   1 
ATOM   2222  C CA  . GLY A 1 321 ? 84.091  96.560  81.577  1.00 9.94  ? 300  GLY A CA  1 
ATOM   2223  C C   . GLY A 1 321 ? 85.434  95.915  81.822  1.00 9.94  ? 300  GLY A C   1 
ATOM   2224  O O   . GLY A 1 321 ? 85.595  95.242  82.844  1.00 9.94  ? 300  GLY A O   1 
ATOM   2225  N N   . GLU A 1 322 ? 86.407  96.100  80.928  1.00 12.38 ? 301  GLU A N   1 
ATOM   2226  C CA  . GLU A 1 322 ? 87.735  95.507  81.072  1.00 12.38 ? 301  GLU A CA  1 
ATOM   2227  C C   . GLU A 1 322 ? 88.526  96.284  82.122  1.00 12.38 ? 301  GLU A C   1 
ATOM   2228  O O   . GLU A 1 322 ? 89.514  96.965  81.844  1.00 12.38 ? 301  GLU A O   1 
ATOM   2229  C CB  . GLU A 1 322 ? 88.464  95.501  79.740  1.00 12.38 ? 301  GLU A CB  1 
ATOM   2230  C CG  . GLU A 1 322 ? 87.720  94.827  78.632  1.00 12.38 ? 301  GLU A CG  1 
ATOM   2231  C CD  . GLU A 1 322 ? 88.070  95.415  77.291  1.00 12.38 ? 301  GLU A CD  1 
ATOM   2232  O OE1 . GLU A 1 322 ? 87.781  94.773  76.265  1.00 12.38 ? 301  GLU A OE1 1 
ATOM   2233  O OE2 . GLU A 1 322 ? 88.633  96.528  77.265  1.00 12.38 ? 301  GLU A OE2 1 
ATOM   2234  N N   . VAL A 1 323 ? 88.055  96.189  83.356  1.00 10.24 ? 302  VAL A N   1 
ATOM   2235  C CA  . VAL A 1 323 ? 88.729  96.781  84.499  1.00 10.24 ? 302  VAL A CA  1 
ATOM   2236  C C   . VAL A 1 323 ? 88.880  95.692  85.543  1.00 10.24 ? 302  VAL A C   1 
ATOM   2237  O O   . VAL A 1 323 ? 87.911  94.994  85.859  1.00 10.24 ? 302  VAL A O   1 
ATOM   2238  C CB  . VAL A 1 323 ? 87.954  97.984  85.072  1.00 10.24 ? 302  VAL A CB  1 
ATOM   2239  C CG1 . VAL A 1 323 ? 88.768  98.683  86.139  1.00 10.24 ? 302  VAL A CG1 1 
ATOM   2240  C CG2 . VAL A 1 323 ? 87.586  98.955  83.968  1.00 10.24 ? 302  VAL A CG2 1 
ATOM   2241  N N   . CYS A 1 324 ? 90.091  95.541  86.075  1.00 13.24 ? 303  CYS A N   1 
ATOM   2242  C CA  . CYS A 1 324 ? 90.308  94.550  87.119  1.00 13.24 ? 303  CYS A CA  1 
ATOM   2243  C C   . CYS A 1 324 ? 89.461  94.834  88.349  1.00 13.24 ? 303  CYS A C   1 
ATOM   2244  O O   . CYS A 1 324 ? 89.232  93.926  89.153  1.00 13.24 ? 303  CYS A O   1 
ATOM   2245  C CB  . CYS A 1 324 ? 91.792  94.497  87.482  1.00 13.24 ? 303  CYS A CB  1 
ATOM   2246  S SG  . CYS A 1 324 ? 92.537  96.106  87.843  1.00 13.24 ? 303  CYS A SG  1 
ATOM   2247  N N   . THR A 1 325 ? 88.977  96.067  88.498  1.00 10.16 ? 304  THR A N   1 
ATOM   2248  C CA  . THR A 1 325 ? 88.093  96.474  89.583  1.00 10.16 ? 304  THR A CA  1 
ATOM   2249  C C   . THR A 1 325 ? 86.717  96.872  89.063  1.00 10.16 ? 304  THR A C   1 
ATOM   2250  O O   . THR A 1 325 ? 86.074  97.755  89.625  1.00 10.16 ? 304  THR A O   1 
ATOM   2251  C CB  . THR A 1 325 ? 88.698  97.634  90.368  1.00 10.16 ? 304  THR A CB  1 
ATOM   2252  O OG1 . THR A 1 325 ? 89.159  98.634  89.454  1.00 10.16 ? 304  THR A OG1 1 
ATOM   2253  C CG2 . THR A 1 325 ? 89.857  97.164  91.200  1.00 10.16 ? 304  THR A CG2 1 
ATOM   2254  N N   . CYS A 1 326 ? 86.270  96.252  87.977  1.00 9.42  ? 305  CYS A N   1 
ATOM   2255  C CA  . CYS A 1 326 ? 84.978  96.593  87.398  1.00 9.42  ? 305  CYS A CA  1 
ATOM   2256  C C   . CYS A 1 326 ? 83.861  96.274  88.384  1.00 9.42  ? 305  CYS A C   1 
ATOM   2257  O O   . CYS A 1 326 ? 83.872  95.198  88.996  1.00 9.42  ? 305  CYS A O   1 
ATOM   2258  C CB  . CYS A 1 326 ? 84.756  95.830  86.096  1.00 9.42  ? 305  CYS A CB  1 
ATOM   2259  S SG  . CYS A 1 326 ? 83.128  96.061  85.354  1.00 9.42  ? 305  CYS A SG  1 
ATOM   2260  N N   . PRO A 1 327 ? 82.892  97.168  88.572  1.00 7.61  ? 306  PRO A N   1 
ATOM   2261  C CA  . PRO A 1 327 ? 81.767  96.893  89.480  1.00 7.61  ? 306  PRO A CA  1 
ATOM   2262  C C   . PRO A 1 327 ? 80.721  95.997  88.827  1.00 7.61  ? 306  PRO A C   1 
ATOM   2263  O O   . PRO A 1 327 ? 79.558  96.369  88.657  1.00 7.61  ? 306  PRO A O   1 
ATOM   2264  C CB  . PRO A 1 327 ? 81.229  98.298  89.770  1.00 7.61  ? 306  PRO A CB  1 
ATOM   2265  C CG  . PRO A 1 327 ? 81.529  99.066  88.536  1.00 7.61  ? 306  PRO A CG  1 
ATOM   2266  C CD  . PRO A 1 327 ? 82.757  98.470  87.901  1.00 7.61  ? 306  PRO A CD  1 
ATOM   2267  N N   . SER A 1 328 ? 81.141  94.792  88.448  1.00 7.26  ? 307  SER A N   1 
ATOM   2268  C CA  . SER A 1 328 ? 80.277  93.861  87.739  1.00 7.26  ? 307  SER A CA  1 
ATOM   2269  C C   . SER A 1 328 ? 79.455  93.008  88.684  1.00 7.26  ? 307  SER A C   1 
ATOM   2270  O O   . SER A 1 328 ? 79.020  91.912  88.312  1.00 7.26  ? 307  SER A O   1 
ATOM   2271  C CB  . SER A 1 328 ? 81.108  92.987  86.801  1.00 7.26  ? 307  SER A CB  1 
ATOM   2272  O OG  . SER A 1 328 ? 82.173  92.366  87.493  1.00 7.26  ? 307  SER A OG  1 
ATOM   2273  N N   . ARG A 1 329 ? 79.234  93.481  89.905  1.00 6.08  ? 308  ARG A N   1 
ATOM   2274  C CA  . ARG A 1 329 ? 78.373  92.783  90.854  1.00 6.08  ? 308  ARG A CA  1 
ATOM   2275  C C   . ARG A 1 329 ? 77.749  93.851  91.755  1.00 6.08  ? 308  ARG A C   1 
ATOM   2276  O O   . ARG A 1 329 ? 78.347  94.270  92.745  1.00 6.08  ? 308  ARG A O   1 
ATOM   2277  C CB  . ARG A 1 329 ? 79.160  91.744  91.638  1.00 6.08  ? 308  ARG A CB  1 
ATOM   2278  C CG  . ARG A 1 329 ? 78.322  90.843  92.504  1.00 6.08  ? 308  ARG A CG  1 
ATOM   2279  C CD  . ARG A 1 329 ? 79.184  89.802  93.190  1.00 6.08  ? 308  ARG A CD  1 
ATOM   2280  N NE  . ARG A 1 329 ? 80.059  90.375  94.202  1.00 6.08  ? 308  ARG A NE  1 
ATOM   2281  C CZ  . ARG A 1 329 ? 81.018  89.697  94.817  1.00 6.08  ? 308  ARG A CZ  1 
ATOM   2282  N NH1 . ARG A 1 329 ? 81.223  88.427  94.513  1.00 6.08  ? 308  ARG A NH1 1 
ATOM   2283  N NH2 . ARG A 1 329 ? 81.772  90.285  95.731  1.00 6.08  ? 308  ARG A NH2 1 
ATOM   2284  N N   . VAL A 1 330 ? 76.548  94.286  91.393  1.00 4.70  ? 309  VAL A N   1 
ATOM   2285  C CA  . VAL A 1 330 ? 75.871  95.393  92.057  1.00 4.70  ? 309  VAL A CA  1 
ATOM   2286  C C   . VAL A 1 330 ? 74.926  94.836  93.109  1.00 4.70  ? 309  VAL A C   1 
ATOM   2287  O O   . VAL A 1 330 ? 74.119  93.948  92.819  1.00 4.70  ? 309  VAL A O   1 
ATOM   2288  C CB  . VAL A 1 330 ? 75.111  96.264  91.046  1.00 4.70  ? 309  VAL A CB  1 
ATOM   2289  C CG1 . VAL A 1 330 ? 74.160  97.182  91.760  1.00 4.70  ? 309  VAL A CG1 1 
ATOM   2290  C CG2 . VAL A 1 330 ? 76.077  97.072  90.224  1.00 4.70  ? 309  VAL A CG2 1 
ATOM   2291  N N   . LEU A 1 331 ? 75.021  95.358  94.328  1.00 5.59  ? 310  LEU A N   1 
ATOM   2292  C CA  . LEU A 1 331 ? 74.195  94.912  95.447  1.00 5.59  ? 310  LEU A CA  1 
ATOM   2293  C C   . LEU A 1 331 ? 73.308  96.080  95.860  1.00 5.59  ? 310  LEU A C   1 
ATOM   2294  O O   . LEU A 1 331 ? 73.742  96.963  96.603  1.00 5.59  ? 310  LEU A O   1 
ATOM   2295  C CB  . LEU A 1 331 ? 75.055  94.443  96.616  1.00 5.59  ? 310  LEU A CB  1 
ATOM   2296  C CG  . LEU A 1 331 ? 76.226  93.519  96.284  1.00 5.59  ? 310  LEU A CG  1 
ATOM   2297  C CD1 . LEU A 1 331 ? 76.915  93.063  97.548  1.00 5.59  ? 310  LEU A CD1 1 
ATOM   2298  C CD2 . LEU A 1 331 ? 75.796  92.344  95.454  1.00 5.59  ? 310  LEU A CD2 1 
ATOM   2299  N N   . ILE A 1 332 ? 72.081  96.092  95.387  1.00 7.60  ? 311  ILE A N   1 
ATOM   2300  C CA  . ILE A 1 332 ? 71.134  97.146  95.725  1.00 7.60  ? 311  ILE A CA  1 
ATOM   2301  C C   . ILE A 1 332 ? 70.315  96.712  96.926  1.00 7.60  ? 311  ILE A C   1 
ATOM   2302  O O   . ILE A 1 332 ? 69.861  95.568  96.997  1.00 7.60  ? 311  ILE A O   1 
ATOM   2303  C CB  . ILE A 1 332 ? 70.226  97.468  94.529  1.00 7.60  ? 311  ILE A CB  1 
ATOM   2304  C CG1 . ILE A 1 332 ? 71.055  97.608  93.266  1.00 7.60  ? 311  ILE A CG1 1 
ATOM   2305  C CG2 . ILE A 1 332 ? 69.471  98.747  94.772  1.00 7.60  ? 311  ILE A CG2 1 
ATOM   2306  C CD1 . ILE A 1 332 ? 70.227  97.812  92.060  1.00 7.60  ? 311  ILE A CD1 1 
ATOM   2307  N N   . GLN A 1 333 ? 70.123  97.622  97.876  1.00 12.04 ? 312  GLN A N   1 
ATOM   2308  C CA  . GLN A 1 333 ? 69.264  97.317  99.009  1.00 12.04 ? 312  GLN A CA  1 
ATOM   2309  C C   . GLN A 1 333 ? 67.869  96.965  98.509  1.00 12.04 ? 312  GLN A C   1 
ATOM   2310  O O   . GLN A 1 333 ? 67.407  97.479  97.488  1.00 12.04 ? 312  GLN A O   1 
ATOM   2311  C CB  . GLN A 1 333 ? 69.212  98.495  99.980  1.00 12.04 ? 312  GLN A CB  1 
ATOM   2312  C CG  . GLN A 1 333 ? 68.757  98.115  101.376 1.00 12.04 ? 312  GLN A CG  1 
ATOM   2313  C CD  . GLN A 1 333 ? 69.317  99.029  102.447 1.00 12.04 ? 312  GLN A CD  1 
ATOM   2314  O OE1 . GLN A 1 333 ? 69.747  100.145 102.167 1.00 12.04 ? 312  GLN A OE1 1 
ATOM   2315  N NE2 . GLN A 1 333 ? 69.317  98.556  103.683 1.00 12.04 ? 312  GLN A NE2 1 
ATOM   2316  N N   . GLU A 1 334 ? 67.208  96.053  99.224  1.00 16.51 ? 313  GLU A N   1 
ATOM   2317  C CA  . GLU A 1 334 ? 65.998  95.430  98.694  1.00 16.51 ? 313  GLU A CA  1 
ATOM   2318  C C   . GLU A 1 334 ? 64.905  96.455  98.427  1.00 16.51 ? 313  GLU A C   1 
ATOM   2319  O O   . GLU A 1 334 ? 64.347  96.505  97.326  1.00 16.51 ? 313  GLU A O   1 
ATOM   2320  C CB  . GLU A 1 334 ? 65.491  94.355  99.652  1.00 16.51 ? 313  GLU A CB  1 
ATOM   2321  C CG  . GLU A 1 334 ? 64.312  93.571  99.109  1.00 16.51 ? 313  GLU A CG  1 
ATOM   2322  C CD  . GLU A 1 334 ? 62.974  94.113  99.580  1.00 16.51 ? 313  GLU A CD  1 
ATOM   2323  O OE1 . GLU A 1 334 ? 62.144  94.479  98.721  1.00 16.51 ? 313  GLU A OE1 1 
ATOM   2324  O OE2 . GLU A 1 334 ? 62.749  94.162  100.809 1.00 16.51 ? 313  GLU A OE2 1 
ATOM   2325  N N   . SER A 1 335 ? 64.577  97.280  99.416  1.00 16.53 ? 314  SER A N   1 
ATOM   2326  C CA  . SER A 1 335 ? 63.475  98.220  99.226  1.00 16.53 ? 314  SER A CA  1 
ATOM   2327  C C   . SER A 1 335 ? 63.938  99.564  98.709  1.00 16.53 ? 314  SER A C   1 
ATOM   2328  O O   . SER A 1 335 ? 63.500  100.606 99.201  1.00 16.53 ? 314  SER A O   1 
ATOM   2329  C CB  . SER A 1 335 ? 62.719  98.389  100.539 1.00 16.53 ? 314  SER A CB  1 
ATOM   2330  O OG  . SER A 1 335 ? 63.311  99.408  101.327 1.00 16.53 ? 314  SER A OG  1 
ATOM   2331  N N   . ILE A 1 336 ? 64.823  99.578  97.717  1.00 14.71 ? 315  ILE A N   1 
ATOM   2332  C CA  . ILE A 1 336 ? 65.069  100.765 96.910  1.00 14.71 ? 315  ILE A CA  1 
ATOM   2333  C C   . ILE A 1 336 ? 65.201  100.284 95.474  1.00 14.71 ? 315  ILE A C   1 
ATOM   2334  O O   . ILE A 1 336 ? 65.416  101.074 94.550  1.00 14.71 ? 315  ILE A O   1 
ATOM   2335  C CB  . ILE A 1 336 ? 66.307  101.542 97.391  1.00 14.71 ? 315  ILE A CB  1 
ATOM   2336  C CG1 . ILE A 1 336 ? 66.237  102.985 96.908  1.00 14.71 ? 315  ILE A CG1 1 
ATOM   2337  C CG2 . ILE A 1 336 ? 67.586  100.898 96.892  1.00 14.71 ? 315  ILE A CG2 1 
ATOM   2338  C CD1 . ILE A 1 336 ? 65.096  103.748 97.521  1.00 14.71 ? 315  ILE A CD1 1 
ATOM   2339  N N   . TYR A 1 337 ? 65.070  98.969  95.292  1.00 15.72 ? 316  TYR A N   1 
ATOM   2340  C CA  . TYR A 1 337 ? 65.394  98.335  94.019  1.00 15.72 ? 316  TYR A CA  1 
ATOM   2341  C C   . TYR A 1 337 ? 64.536  98.864  92.879  1.00 15.72 ? 316  TYR A C   1 
ATOM   2342  O O   . TYR A 1 337 ? 65.016  98.999  91.748  1.00 15.72 ? 316  TYR A O   1 
ATOM   2343  C CB  . TYR A 1 337 ? 65.233  96.822  94.144  1.00 15.72 ? 316  TYR A CB  1 
ATOM   2344  C CG  . TYR A 1 337 ? 65.605  96.068  92.892  1.00 15.72 ? 316  TYR A CG  1 
ATOM   2345  C CD1 . TYR A 1 337 ? 64.661  95.806  91.909  1.00 15.72 ? 316  TYR A CD1 1 
ATOM   2346  C CD2 . TYR A 1 337 ? 66.901  95.625  92.685  1.00 15.72 ? 316  TYR A CD2 1 
ATOM   2347  C CE1 . TYR A 1 337 ? 64.996  95.126  90.765  1.00 15.72 ? 316  TYR A CE1 1 
ATOM   2348  C CE2 . TYR A 1 337 ? 67.243  94.938  91.541  1.00 15.72 ? 316  TYR A CE2 1 
ATOM   2349  C CZ  . TYR A 1 337 ? 66.286  94.692  90.588  1.00 15.72 ? 316  TYR A CZ  1 
ATOM   2350  O OH  . TYR A 1 337 ? 66.618  94.016  89.445  1.00 15.72 ? 316  TYR A OH  1 
ATOM   2351  N N   . ASP A 1 338 ? 63.264  99.158  93.148  1.00 15.35 ? 317  ASP A N   1 
ATOM   2352  C CA  . ASP A 1 338 ? 62.343  99.534  92.079  1.00 15.35 ? 317  ASP A CA  1 
ATOM   2353  C C   . ASP A 1 338 ? 62.790  100.816 91.383  1.00 15.35 ? 317  ASP A C   1 
ATOM   2354  O O   . ASP A 1 338 ? 63.053  100.826 90.171  1.00 15.35 ? 317  ASP A O   1 
ATOM   2355  C CB  . ASP A 1 338 ? 60.931  99.688  92.645  1.00 15.35 ? 317  ASP A CB  1 
ATOM   2356  C CG  . ASP A 1 338 ? 60.328  98.364  93.069  1.00 15.35 ? 317  ASP A CG  1 
ATOM   2357  O OD1 . ASP A 1 338 ? 60.906  97.310  92.731  1.00 15.35 ? 317  ASP A OD1 1 
ATOM   2358  O OD2 . ASP A 1 338 ? 59.270  98.377  93.732  1.00 15.35 ? 317  ASP A OD2 1 
ATOM   2359  N N   . LYS A 1 339 ? 62.872  101.912 92.142  1.00 13.74 ? 318  LYS A N   1 
ATOM   2360  C CA  . LYS A 1 339 ? 63.265  103.196 91.572  1.00 13.74 ? 318  LYS A CA  1 
ATOM   2361  C C   . LYS A 1 339 ? 64.650  103.116 90.948  1.00 13.74 ? 318  LYS A C   1 
ATOM   2362  O O   . LYS A 1 339 ? 64.877  103.601 89.830  1.00 13.74 ? 318  LYS A O   1 
ATOM   2363  C CB  . LYS A 1 339 ? 63.245  104.275 92.653  1.00 13.74 ? 318  LYS A CB  1 
ATOM   2364  C CG  . LYS A 1 339 ? 62.142  104.127 93.677  1.00 13.74 ? 318  LYS A CG  1 
ATOM   2365  C CD  . LYS A 1 339 ? 62.499  104.868 94.955  1.00 13.74 ? 318  LYS A CD  1 
ATOM   2366  C CE  . LYS A 1 339 ? 62.482  106.372 94.743  1.00 13.74 ? 318  LYS A CE  1 
ATOM   2367  N NZ  . LYS A 1 339 ? 62.909  107.110 95.963  1.00 13.74 ? 318  LYS A NZ  1 
ATOM   2368  N N   . PHE A 1 340 ? 65.596  102.513 91.670  1.00 11.09 ? 319  PHE A N   1 
ATOM   2369  C CA  . PHE A 1 340 ? 66.969  102.503 91.195  1.00 11.09 ? 319  PHE A CA  1 
ATOM   2370  C C   . PHE A 1 340 ? 67.089  101.737 89.891  1.00 11.09 ? 319  PHE A C   1 
ATOM   2371  O O   . PHE A 1 340 ? 67.758  102.195 88.967  1.00 11.09 ? 319  PHE A O   1 
ATOM   2372  C CB  . PHE A 1 340 ? 67.910  101.919 92.245  1.00 11.09 ? 319  PHE A CB  1 
ATOM   2373  C CG  . PHE A 1 340 ? 69.359  102.096 91.904  1.00 11.09 ? 319  PHE A CG  1 
ATOM   2374  C CD1 . PHE A 1 340 ? 70.015  101.185 91.098  1.00 11.09 ? 319  PHE A CD1 1 
ATOM   2375  C CD2 . PHE A 1 340 ? 70.056  103.194 92.362  1.00 11.09 ? 319  PHE A CD2 1 
ATOM   2376  C CE1 . PHE A 1 340 ? 71.339  101.358 90.771  1.00 11.09 ? 319  PHE A CE1 1 
ATOM   2377  C CE2 . PHE A 1 340 ? 71.380  103.371 92.037  1.00 11.09 ? 319  PHE A CE2 1 
ATOM   2378  C CZ  . PHE A 1 340 ? 72.022  102.451 91.241  1.00 11.09 ? 319  PHE A CZ  1 
ATOM   2379  N N   . MET A 1 341 ? 66.443  100.576 89.785  1.00 12.52 ? 320  MET A N   1 
ATOM   2380  C CA  . MET A 1 341 ? 66.555  99.830  88.537  1.00 12.52 ? 320  MET A CA  1 
ATOM   2381  C C   . MET A 1 341 ? 65.780  100.461 87.396  1.00 12.52 ? 320  MET A C   1 
ATOM   2382  O O   . MET A 1 341 ? 66.250  100.406 86.259  1.00 12.52 ? 320  MET A O   1 
ATOM   2383  C CB  . MET A 1 341 ? 66.150  98.374  88.722  1.00 12.52 ? 320  MET A CB  1 
ATOM   2384  C CG  . MET A 1 341 ? 67.334  97.534  89.103  1.00 12.52 ? 320  MET A CG  1 
ATOM   2385  S SD  . MET A 1 341 ? 68.556  97.834  87.809  1.00 12.52 ? 320  MET A SD  1 
ATOM   2386  C CE  . MET A 1 341 ? 70.079  97.400  88.615  1.00 12.52 ? 320  MET A CE  1 
ATOM   2387  N N   . GLU A 1 342 ? 64.630  101.089 87.642  1.00 14.45 ? 321  GLU A N   1 
ATOM   2388  C CA  . GLU A 1 342 ? 63.971  101.729 86.508  1.00 14.45 ? 321  GLU A CA  1 
ATOM   2389  C C   . GLU A 1 342 ? 64.822  102.881 85.974  1.00 14.45 ? 321  GLU A C   1 
ATOM   2390  O O   . GLU A 1 342 ? 65.115  102.945 84.768  1.00 14.45 ? 321  GLU A O   1 
ATOM   2391  C CB  . GLU A 1 342 ? 62.549  102.169 86.880  1.00 14.45 ? 321  GLU A CB  1 
ATOM   2392  C CG  . GLU A 1 342 ? 62.403  103.171 88.001  1.00 14.45 ? 321  GLU A CG  1 
ATOM   2393  C CD  . GLU A 1 342 ? 62.212  104.586 87.500  1.00 14.45 ? 321  GLU A CD  1 
ATOM   2394  O OE1 . GLU A 1 342 ? 61.791  104.753 86.336  1.00 14.45 ? 321  GLU A OE1 1 
ATOM   2395  O OE2 . GLU A 1 342 ? 62.471  105.531 88.274  1.00 14.45 ? 321  GLU A OE2 1 
ATOM   2396  N N   . ARG A 1 343 ? 65.317  103.743 86.871  1.00 12.92 ? 322  ARG A N   1 
ATOM   2397  C CA  . ARG A 1 343 ? 66.163  104.852 86.435  1.00 12.92 ? 322  ARG A CA  1 
ATOM   2398  C C   . ARG A 1 343 ? 67.480  104.359 85.842  1.00 12.92 ? 322  ARG A C   1 
ATOM   2399  O O   . ARG A 1 343 ? 67.969  104.913 84.851  1.00 12.92 ? 322  ARG A O   1 
ATOM   2400  C CB  . ARG A 1 343 ? 66.421  105.797 87.602  1.00 12.92 ? 322  ARG A CB  1 
ATOM   2401  C CG  . ARG A 1 343 ? 65.344  106.835 87.781  1.00 12.92 ? 322  ARG A CG  1 
ATOM   2402  C CD  . ARG A 1 343 ? 65.824  107.985 88.629  1.00 12.92 ? 322  ARG A CD  1 
ATOM   2403  N NE  . ARG A 1 343 ? 65.104  109.215 88.325  1.00 12.92 ? 322  ARG A NE  1 
ATOM   2404  C CZ  . ARG A 1 343 ? 65.295  110.367 88.957  1.00 12.92 ? 322  ARG A CZ  1 
ATOM   2405  N NH1 . ARG A 1 343 ? 66.186  110.448 89.934  1.00 12.92 ? 322  ARG A NH1 1 
ATOM   2406  N NH2 . ARG A 1 343 ? 64.592  111.437 88.612  1.00 12.92 ? 322  ARG A NH2 1 
ATOM   2407  N N   . ALA A 1 344 ? 68.058  103.307 86.422  1.00 11.86 ? 323  ALA A N   1 
ATOM   2408  C CA  . ALA A 1 344 ? 69.364  102.830 85.997  1.00 11.86 ? 323  ALA A CA  1 
ATOM   2409  C C   . ALA A 1 344 ? 69.291  102.106 84.663  1.00 11.86 ? 323  ALA A C   1 
ATOM   2410  O O   . ALA A 1 344 ? 70.207  102.218 83.848  1.00 11.86 ? 323  ALA A O   1 
ATOM   2411  C CB  . ALA A 1 344 ? 69.950  101.922 87.070  1.00 11.86 ? 323  ALA A CB  1 
ATOM   2412  N N   . VAL A 1 345 ? 68.222  101.349 84.419  1.00 13.27 ? 324  VAL A N   1 
ATOM   2413  C CA  . VAL A 1 345 ? 68.061  100.728 83.113  1.00 13.27 ? 324  VAL A CA  1 
ATOM   2414  C C   . VAL A 1 345 ? 67.812  101.795 82.060  1.00 13.27 ? 324  VAL A C   1 
ATOM   2415  O O   . VAL A 1 345 ? 68.327  101.708 80.936  1.00 13.27 ? 324  VAL A O   1 
ATOM   2416  C CB  . VAL A 1 345 ? 66.940  99.676  83.154  1.00 13.27 ? 324  VAL A CB  1 
ATOM   2417  C CG1 . VAL A 1 345 ? 66.594  99.211  81.756  1.00 13.27 ? 324  VAL A CG1 1 
ATOM   2418  C CG2 . VAL A 1 345 ? 67.371  98.493  84.000  1.00 13.27 ? 324  VAL A CG2 1 
ATOM   2419  N N   . GLN A 1 346 ? 67.054  102.839 82.411  1.00 15.01 ? 325  GLN A N   1 
ATOM   2420  C CA  . GLN A 1 346 ? 66.929  103.978 81.507  1.00 15.01 ? 325  GLN A CA  1 
ATOM   2421  C C   . GLN A 1 346 ? 68.300  104.547 81.149  1.00 15.01 ? 325  GLN A C   1 
ATOM   2422  O O   . GLN A 1 346 ? 68.639  104.697 79.968  1.00 15.01 ? 325  GLN A O   1 
ATOM   2423  C CB  . GLN A 1 346 ? 66.048  105.048 82.149  1.00 15.01 ? 325  GLN A CB  1 
ATOM   2424  C CG  . GLN A 1 346 ? 65.783  106.253 81.274  1.00 15.01 ? 325  GLN A CG  1 
ATOM   2425  C CD  . GLN A 1 346 ? 65.677  107.532 82.077  1.00 15.01 ? 325  GLN A CD  1 
ATOM   2426  O OE1 . GLN A 1 346 ? 66.618  107.928 82.764  1.00 15.01 ? 325  GLN A OE1 1 
ATOM   2427  N NE2 . GLN A 1 346 ? 64.524  108.185 81.999  1.00 15.01 ? 325  GLN A NE2 1 
ATOM   2428  N N   . ARG A 1 347 ? 69.118  104.835 82.163  1.00 14.41 ? 326  ARG A N   1 
ATOM   2429  C CA  . ARG A 1 347 ? 70.416  105.469 81.953  1.00 14.41 ? 326  ARG A CA  1 
ATOM   2430  C C   . ARG A 1 347 ? 71.466  104.541 81.355  1.00 14.41 ? 326  ARG A C   1 
ATOM   2431  O O   . ARG A 1 347 ? 72.478  105.033 80.851  1.00 14.41 ? 326  ARG A O   1 
ATOM   2432  C CB  . ARG A 1 347 ? 70.932  106.042 83.269  1.00 14.41 ? 326  ARG A CB  1 
ATOM   2433  C CG  . ARG A 1 347 ? 70.156  107.255 83.733  1.00 14.41 ? 326  ARG A CG  1 
ATOM   2434  C CD  . ARG A 1 347 ? 70.687  107.787 85.042  1.00 14.41 ? 326  ARG A CD  1 
ATOM   2435  N NE  . ARG A 1 347 ? 71.609  108.898 84.848  1.00 14.41 ? 326  ARG A NE  1 
ATOM   2436  C CZ  . ARG A 1 347 ? 72.918  108.752 84.694  1.00 14.41 ? 326  ARG A CZ  1 
ATOM   2437  N NH1 . ARG A 1 347 ? 73.452  107.542 84.714  1.00 14.41 ? 326  ARG A NH1 1 
ATOM   2438  N NH2 . ARG A 1 347 ? 73.692  109.813 84.525  1.00 14.41 ? 326  ARG A NH2 1 
ATOM   2439  N N   . VAL A 1 348 ? 71.268  103.229 81.412  1.00 12.75 ? 327  VAL A N   1 
ATOM   2440  C CA  . VAL A 1 348 ? 72.158  102.296 80.727  1.00 12.75 ? 327  VAL A CA  1 
ATOM   2441  C C   . VAL A 1 348 ? 71.767  102.143 79.264  1.00 12.75 ? 327  VAL A C   1 
ATOM   2442  O O   . VAL A 1 348 ? 72.632  102.024 78.394  1.00 12.75 ? 327  VAL A O   1 
ATOM   2443  C CB  . VAL A 1 348 ? 72.171  100.940 81.458  1.00 12.75 ? 327  VAL A CB  1 
ATOM   2444  C CG1 . VAL A 1 348 ? 72.853  99.882  80.618  1.00 12.75 ? 327  VAL A CG1 1 
ATOM   2445  C CG2 . VAL A 1 348 ? 72.892  101.071 82.773  1.00 12.75 ? 327  VAL A CG2 1 
ATOM   2446  N N   . GLN A 1 349 ? 70.465  102.150 78.965  1.00 16.21 ? 328  GLN A N   1 
ATOM   2447  C CA  . GLN A 1 349 ? 70.046  102.281 77.576  1.00 16.21 ? 328  GLN A CA  1 
ATOM   2448  C C   . GLN A 1 349 ? 70.531  103.595 76.983  1.00 16.21 ? 328  GLN A C   1 
ATOM   2449  O O   . GLN A 1 349 ? 70.813  103.670 75.782  1.00 16.21 ? 328  GLN A O   1 
ATOM   2450  C CB  . GLN A 1 349 ? 68.526  102.191 77.467  1.00 16.21 ? 328  GLN A CB  1 
ATOM   2451  C CG  . GLN A 1 349 ? 67.974  100.785 77.487  1.00 16.21 ? 328  GLN A CG  1 
ATOM   2452  C CD  . GLN A 1 349 ? 66.485  100.762 77.756  1.00 16.21 ? 328  GLN A CD  1 
ATOM   2453  O OE1 . GLN A 1 349 ? 66.041  100.316 78.812  1.00 16.21 ? 328  GLN A OE1 1 
ATOM   2454  N NE2 . GLN A 1 349 ? 65.704  101.247 76.801  1.00 16.21 ? 328  GLN A NE2 1 
ATOM   2455  N N   . ALA A 1 350 ? 70.637  104.638 77.809  1.00 15.67 ? 329  ALA A N   1 
ATOM   2456  C CA  . ALA A 1 350 ? 71.129  105.928 77.344  1.00 15.67 ? 329  ALA A CA  1 
ATOM   2457  C C   . ALA A 1 350 ? 72.615  105.922 77.007  1.00 15.67 ? 329  ALA A C   1 
ATOM   2458  O O   . ALA A 1 350 ? 73.089  106.889 76.405  1.00 15.67 ? 329  ALA A O   1 
ATOM   2459  C CB  . ALA A 1 350 ? 70.850  107.005 78.393  1.00 15.67 ? 329  ALA A CB  1 
ATOM   2460  N N   . ILE A 1 351 ? 73.363  104.885 77.390  1.00 16.36 ? 330  ILE A N   1 
ATOM   2461  C CA  . ILE A 1 351 ? 74.771  104.809 77.010  1.00 16.36 ? 330  ILE A CA  1 
ATOM   2462  C C   . ILE A 1 351 ? 74.866  104.776 75.494  1.00 16.36 ? 330  ILE A C   1 
ATOM   2463  O O   . ILE A 1 351 ? 74.278  103.907 74.840  1.00 16.36 ? 330  ILE A O   1 
ATOM   2464  C CB  . ILE A 1 351 ? 75.445  103.580 77.629  1.00 16.36 ? 330  ILE A CB  1 
ATOM   2465  C CG1 . ILE A 1 351 ? 75.525  103.699 79.148  1.00 16.36 ? 330  ILE A CG1 1 
ATOM   2466  C CG2 . ILE A 1 351 ? 76.835  103.408 77.067  1.00 16.36 ? 330  ILE A CG2 1 
ATOM   2467  C CD1 . ILE A 1 351 ? 76.065  102.460 79.818  1.00 16.36 ? 330  ILE A CD1 1 
ATOM   2468  N N   . LYS A 1 352 ? 75.601  105.726 74.925  1.00 16.24 ? 331  LYS A N   1 
ATOM   2469  C CA  . LYS A 1 352 ? 75.726  105.825 73.475  1.00 16.24 ? 331  LYS A CA  1 
ATOM   2470  C C   . LYS A 1 352 ? 76.873  104.940 73.008  1.00 16.24 ? 331  LYS A C   1 
ATOM   2471  O O   . LYS A 1 352 ? 78.034  105.189 73.342  1.00 16.24 ? 331  LYS A O   1 
ATOM   2472  C CB  . LYS A 1 352 ? 75.947  107.273 73.050  1.00 16.24 ? 331  LYS A CB  1 
ATOM   2473  C CG  . LYS A 1 352 ? 76.305  107.416 71.585  1.00 16.24 ? 331  LYS A CG  1 
ATOM   2474  C CD  . LYS A 1 352 ? 76.404  108.867 71.171  1.00 16.24 ? 331  LYS A CD  1 
ATOM   2475  C CE  . LYS A 1 352 ? 76.542  108.995 69.659  1.00 16.24 ? 331  LYS A CE  1 
ATOM   2476  N NZ  . LYS A 1 352 ? 77.851  108.495 69.158  1.00 16.24 ? 331  LYS A NZ  1 
ATOM   2477  N N   . GLN A 1 353 ? 76.551  103.912 72.233  1.00 18.35 ? 332  GLN A N   1 
ATOM   2478  C CA  . GLN A 1 353 ? 77.548  103.025 71.653  1.00 18.35 ? 332  GLN A CA  1 
ATOM   2479  C C   . GLN A 1 353 ? 77.827  103.461 70.223  1.00 18.35 ? 332  GLN A C   1 
ATOM   2480  O O   . GLN A 1 353 ? 76.897  103.656 69.436  1.00 18.35 ? 332  GLN A O   1 
ATOM   2481  C CB  . GLN A 1 353 ? 77.073  101.572 71.679  1.00 18.35 ? 332  GLN A CB  1 
ATOM   2482  C CG  . GLN A 1 353 ? 76.409  101.150 72.980  1.00 18.35 ? 332  GLN A CG  1 
ATOM   2483  C CD  . GLN A 1 353 ? 74.896  101.155 72.895  1.00 18.35 ? 332  GLN A CD  1 
ATOM   2484  O OE1 . GLN A 1 353 ? 74.301  101.993 72.217  1.00 18.35 ? 332  GLN A OE1 1 
ATOM   2485  N NE2 . GLN A 1 353 ? 74.266  100.211 73.579  1.00 18.35 ? 332  GLN A NE2 1 
ATOM   2486  N N   . GLY A 1 354 ? 79.098  103.612 69.892  1.00 16.04 ? 333  GLY A N   1 
ATOM   2487  C CA  . GLY A 1 354 ? 79.453  104.052 68.564  1.00 16.04 ? 333  GLY A CA  1 
ATOM   2488  C C   . GLY A 1 354 ? 80.924  103.860 68.306  1.00 16.04 ? 333  GLY A C   1 
ATOM   2489  O O   . GLY A 1 354 ? 81.606  103.133 69.028  1.00 16.04 ? 333  GLY A O   1 
ATOM   2490  N N   . ASP A 1 355 ? 81.404  104.516 67.260  1.00 15.23 ? 334  ASP A N   1 
ATOM   2491  C CA  . ASP A 1 355 ? 82.825  104.504 66.958  1.00 15.23 ? 334  ASP A CA  1 
ATOM   2492  C C   . ASP A 1 355 ? 83.583  105.108 68.135  1.00 15.23 ? 334  ASP A C   1 
ATOM   2493  O O   . ASP A 1 355 ? 83.326  106.265 68.496  1.00 15.23 ? 334  ASP A O   1 
ATOM   2494  C CB  . ASP A 1 355 ? 83.093  105.295 65.681  1.00 15.23 ? 334  ASP A CB  1 
ATOM   2495  C CG  . ASP A 1 355 ? 84.504  105.117 65.158  1.00 15.23 ? 334  ASP A CG  1 
ATOM   2496  O OD1 . ASP A 1 355 ? 85.396  104.712 65.927  1.00 15.23 ? 334  ASP A OD1 1 
ATOM   2497  O OD2 . ASP A 1 355 ? 84.725  105.390 63.961  1.00 15.23 ? 334  ASP A OD2 1 
ATOM   2498  N N   . PRO A 1 356 ? 84.519  104.381 68.748  1.00 12.95 ? 335  PRO A N   1 
ATOM   2499  C CA  . PRO A 1 356 ? 85.226  104.926 69.917  1.00 12.95 ? 335  PRO A CA  1 
ATOM   2500  C C   . PRO A 1 356 ? 86.023  106.177 69.621  1.00 12.95 ? 335  PRO A C   1 
ATOM   2501  O O   . PRO A 1 356 ? 86.374  106.904 70.556  1.00 12.95 ? 335  PRO A O   1 
ATOM   2502  C CB  . PRO A 1 356 ? 86.140  103.771 70.340  1.00 12.95 ? 335  PRO A CB  1 
ATOM   2503  C CG  . PRO A 1 356 ? 85.484  102.559 69.802  1.00 12.95 ? 335  PRO A CG  1 
ATOM   2504  C CD  . PRO A 1 356 ? 84.855  102.969 68.512  1.00 12.95 ? 335  PRO A CD  1 
ATOM   2505  N N   . ARG A 1 357 ? 86.330  106.448 68.355  1.00 13.56 ? 336  ARG A N   1 
ATOM   2506  C CA  . ARG A 1 357 ? 87.078  107.638 67.981  1.00 13.56 ? 336  ARG A CA  1 
ATOM   2507  C C   . ARG A 1 357 ? 86.204  108.882 67.910  1.00 13.56 ? 336  ARG A C   1 
ATOM   2508  O O   . ARG A 1 357 ? 86.732  109.981 67.716  1.00 13.56 ? 336  ARG A O   1 
ATOM   2509  C CB  . ARG A 1 357 ? 87.778  107.392 66.647  1.00 13.56 ? 336  ARG A CB  1 
ATOM   2510  C CG  . ARG A 1 357 ? 88.341  105.988 66.552  1.00 13.56 ? 336  ARG A CG  1 
ATOM   2511  C CD  . ARG A 1 357 ? 89.082  105.746 65.258  1.00 13.56 ? 336  ARG A CD  1 
ATOM   2512  N NE  . ARG A 1 357 ? 88.164  105.474 64.158  1.00 13.56 ? 336  ARG A NE  1 
ATOM   2513  C CZ  . ARG A 1 357 ? 88.269  104.433 63.341  1.00 13.56 ? 336  ARG A CZ  1 
ATOM   2514  N NH1 . ARG A 1 357 ? 89.248  103.557 63.505  1.00 13.56 ? 336  ARG A NH1 1 
ATOM   2515  N NH2 . ARG A 1 357 ? 87.390  104.264 62.365  1.00 13.56 ? 336  ARG A NH2 1 
ATOM   2516  N N   . GLU A 1 358 ? 84.893  108.737 68.064  1.00 16.65 ? 337  GLU A N   1 
ATOM   2517  C CA  . GLU A 1 358 ? 84.009  109.884 68.195  1.00 16.65 ? 337  GLU A CA  1 
ATOM   2518  C C   . GLU A 1 358 ? 84.014  110.381 69.632  1.00 16.65 ? 337  GLU A C   1 
ATOM   2519  O O   . GLU A 1 358 ? 84.024  109.589 70.577  1.00 16.65 ? 337  GLU A O   1 
ATOM   2520  C CB  . GLU A 1 358 ? 82.586  109.516 67.779  1.00 16.65 ? 337  GLU A CB  1 
ATOM   2521  C CG  . GLU A 1 358 ? 82.491  108.816 66.442  1.00 16.65 ? 337  GLU A CG  1 
ATOM   2522  C CD  . GLU A 1 358 ? 83.143  109.607 65.332  1.00 16.65 ? 337  GLU A CD  1 
ATOM   2523  O OE1 . GLU A 1 358 ? 84.055  109.070 64.670  1.00 16.65 ? 337  GLU A OE1 1 
ATOM   2524  O OE2 . GLU A 1 358 ? 82.747  110.772 65.124  1.00 16.65 ? 337  GLU A OE2 1 
ATOM   2525  N N   . SER A 1 359 ? 84.010  111.703 69.796  1.00 14.87 ? 338  SER A N   1 
ATOM   2526  C CA  . SER A 1 359 ? 84.036  112.274 71.136  1.00 14.87 ? 338  SER A CA  1 
ATOM   2527  C C   . SER A 1 359 ? 82.753  112.000 71.907  1.00 14.87 ? 338  SER A C   1 
ATOM   2528  O O   . SER A 1 359 ? 82.756  112.080 73.140  1.00 14.87 ? 338  SER A O   1 
ATOM   2529  C CB  . SER A 1 359 ? 84.286  113.778 71.060  1.00 14.87 ? 338  SER A CB  1 
ATOM   2530  O OG  . SER A 1 359 ? 85.417  114.065 70.259  1.00 14.87 ? 338  SER A OG  1 
ATOM   2531  N N   . ASP A 1 360 ? 81.660  111.683 71.215  1.00 15.41 ? 339  ASP A N   1 
ATOM   2532  C CA  . ASP A 1 360 ? 80.391  111.415 71.875  1.00 15.41 ? 339  ASP A CA  1 
ATOM   2533  C C   . ASP A 1 360 ? 80.237  109.966 72.307  1.00 15.41 ? 339  ASP A C   1 
ATOM   2534  O O   . ASP A 1 360 ? 79.432  109.687 73.202  1.00 15.41 ? 339  ASP A O   1 
ATOM   2535  C CB  . ASP A 1 360 ? 79.226  111.798 70.957  1.00 15.41 ? 339  ASP A CB  1 
ATOM   2536  C CG  . ASP A 1 360 ? 79.422  111.317 69.535  1.00 15.41 ? 339  ASP A CG  1 
ATOM   2537  O OD1 . ASP A 1 360 ? 79.703  110.116 69.340  1.00 15.41 ? 339  ASP A OD1 1 
ATOM   2538  O OD2 . ASP A 1 360 ? 79.297  112.141 68.606  1.00 15.41 ? 339  ASP A OD2 1 
ATOM   2539  N N   . THR A 1 361 ? 80.977  109.049 71.690  1.00 14.59 ? 340  THR A N   1 
ATOM   2540  C CA  . THR A 1 361 ? 80.895  107.640 72.047  1.00 14.59 ? 340  THR A CA  1 
ATOM   2541  C C   . THR A 1 361 ? 81.225  107.442 73.519  1.00 14.59 ? 340  THR A C   1 
ATOM   2542  O O   . THR A 1 361 ? 82.167  108.035 74.047  1.00 14.59 ? 340  THR A O   1 
ATOM   2543  C CB  . THR A 1 361 ? 81.851  106.825 71.181  1.00 14.59 ? 340  THR A CB  1 
ATOM   2544  O OG1 . THR A 1 361 ? 81.515  107.008 69.803  1.00 14.59 ? 340  THR A OG1 1 
ATOM   2545  C CG2 . THR A 1 361 ? 81.762  105.352 71.514  1.00 14.59 ? 340  THR A CG2 1 
ATOM   2546  N N   . MET A 1 362 ? 80.438  106.599 74.184  1.00 13.95 ? 341  MET A N   1 
ATOM   2547  C CA  . MET A 1 362 ? 80.577  106.380 75.612  1.00 13.95 ? 341  MET A CA  1 
ATOM   2548  C C   . MET A 1 362 ? 81.149  105.017 75.965  1.00 13.95 ? 341  MET A C   1 
ATOM   2549  O O   . MET A 1 362 ? 81.576  104.823 77.106  1.00 13.95 ? 341  MET A O   1 
ATOM   2550  C CB  . MET A 1 362 ? 79.213  106.539 76.294  1.00 13.95 ? 341  MET A CB  1 
ATOM   2551  C CG  . MET A 1 362 ? 78.692  107.952 76.238  1.00 13.95 ? 341  MET A CG  1 
ATOM   2552  S SD  . MET A 1 362 ? 77.090  108.163 77.019  1.00 13.95 ? 341  MET A SD  1 
ATOM   2553  C CE  . MET A 1 362 ? 76.780  109.888 76.664  1.00 13.95 ? 341  MET A CE  1 
ATOM   2554  N N   . ILE A 1 363 ? 81.169  104.077 75.025  1.00 10.68 ? 342  ILE A N   1 
ATOM   2555  C CA  . ILE A 1 363 ? 81.672  102.730 75.272  1.00 10.68 ? 342  ILE A CA  1 
ATOM   2556  C C   . ILE A 1 363 ? 82.236  102.189 73.968  1.00 10.68 ? 342  ILE A C   1 
ATOM   2557  O O   . ILE A 1 363 ? 81.611  102.314 72.912  1.00 10.68 ? 342  ILE A O   1 
ATOM   2558  C CB  . ILE A 1 363 ? 80.572  101.812 75.844  1.00 10.68 ? 342  ILE A CB  1 
ATOM   2559  C CG1 . ILE A 1 363 ? 81.084  100.383 76.008  1.00 10.68 ? 342  ILE A CG1 1 
ATOM   2560  C CG2 . ILE A 1 363 ? 79.334  101.843 74.975  1.00 10.68 ? 342  ILE A CG2 1 
ATOM   2561  C CD1 . ILE A 1 363 ? 80.261  99.557  76.962  1.00 10.68 ? 342  ILE A CD1 1 
ATOM   2562  N N   . GLY A 1 364 ? 83.425  101.599 74.035  1.00 10.52 ? 343  GLY A N   1 
ATOM   2563  C CA  . GLY A 1 364 ? 84.128  101.191 72.835  1.00 10.52 ? 343  GLY A CA  1 
ATOM   2564  C C   . GLY A 1 364 ? 84.066  99.710  72.531  1.00 10.52 ? 343  GLY A C   1 
ATOM   2565  O O   . GLY A 1 364 ? 83.058  99.053  72.797  1.00 10.52 ? 343  GLY A O   1 
ATOM   2566  N N   . ALA A 1 365 ? 85.137  99.177  71.963  1.00 10.93 ? 344  ALA A N   1 
ATOM   2567  C CA  . ALA A 1 365 ? 85.198  97.778  71.584  1.00 10.93 ? 344  ALA A CA  1 
ATOM   2568  C C   . ALA A 1 365 ? 85.843  96.948  72.687  1.00 10.93 ? 344  ALA A C   1 
ATOM   2569  O O   . ALA A 1 365 ? 86.425  97.471  73.636  1.00 10.93 ? 344  ALA A O   1 
ATOM   2570  C CB  . ALA A 1 365 ? 85.974  97.615  70.279  1.00 10.93 ? 344  ALA A CB  1 
ATOM   2571  N N   . GLN A 1 366 ? 85.731  95.633  72.557  1.00 12.39 ? 345  GLN A N   1 
ATOM   2572  C CA  . GLN A 1 366 ? 86.467  94.733  73.426  1.00 12.39 ? 345  GLN A CA  1 
ATOM   2573  C C   . GLN A 1 366 ? 87.858  94.503  72.852  1.00 12.39 ? 345  GLN A C   1 
ATOM   2574  O O   . GLN A 1 366 ? 88.047  94.459  71.634  1.00 12.39 ? 345  GLN A O   1 
ATOM   2575  C CB  . GLN A 1 366 ? 85.732  93.406  73.599  1.00 12.39 ? 345  GLN A CB  1 
ATOM   2576  C CG  . GLN A 1 366 ? 84.288  93.554  74.032  1.00 12.39 ? 345  GLN A CG  1 
ATOM   2577  C CD  . GLN A 1 366 ? 84.136  94.344  75.314  1.00 12.39 ? 345  GLN A CD  1 
ATOM   2578  O OE1 . GLN A 1 366 ? 83.313  95.253  75.400  1.00 12.39 ? 345  GLN A OE1 1 
ATOM   2579  N NE2 . GLN A 1 366 ? 84.926  93.998  76.319  1.00 12.39 ? 345  GLN A NE2 1 
ATOM   2580  N N   . ALA A 1 367 ? 88.834  94.348  73.747  1.00 13.32 ? 346  ALA A N   1 
ATOM   2581  C CA  . ALA A 1 367 ? 90.235  94.422  73.353  1.00 13.32 ? 346  ALA A CA  1 
ATOM   2582  C C   . ALA A 1 367 ? 90.638  93.335  72.366  1.00 13.32 ? 346  ALA A C   1 
ATOM   2583  O O   . ALA A 1 367 ? 91.654  93.490  71.679  1.00 13.32 ? 346  ALA A O   1 
ATOM   2584  C CB  . ALA A 1 367 ? 91.123  94.355  74.591  1.00 13.32 ? 346  ALA A CB  1 
ATOM   2585  N N   . SER A 1 368 ? 89.881  92.245  72.271  1.00 14.84 ? 347  SER A N   1 
ATOM   2586  C CA  . SER A 1 368 ? 90.229  91.181  71.340  1.00 14.84 ? 347  SER A CA  1 
ATOM   2587  C C   . SER A 1 368 ? 88.990  90.355  71.036  1.00 14.84 ? 347  SER A C   1 
ATOM   2588  O O   . SER A 1 368 ? 87.987  90.421  71.749  1.00 14.84 ? 347  SER A O   1 
ATOM   2589  C CB  . SER A 1 368 ? 91.351  90.297  71.894  1.00 14.84 ? 347  SER A CB  1 
ATOM   2590  O OG  . SER A 1 368 ? 90.949  89.646  73.085  1.00 14.84 ? 347  SER A OG  1 
ATOM   2591  N N   . SER A 1 369 ? 89.077  89.577  69.954  1.00 18.49 ? 348  SER A N   1 
ATOM   2592  C CA  . SER A 1 369 ? 87.964  88.717  69.565  1.00 18.49 ? 348  SER A CA  1 
ATOM   2593  C C   . SER A 1 369 ? 87.782  87.567  70.546  1.00 18.49 ? 348  SER A C   1 
ATOM   2594  O O   . SER A 1 369 ? 86.650  87.149  70.821  1.00 18.49 ? 348  SER A O   1 
ATOM   2595  C CB  . SER A 1 369 ? 88.188  88.180  68.153  1.00 18.49 ? 348  SER A CB  1 
ATOM   2596  O OG  . SER A 1 369 ? 86.978  87.694  67.598  1.00 18.49 ? 348  SER A OG  1 
ATOM   2597  N N   . GLU A 1 370 ? 88.887  87.039  71.077  1.00 19.61 ? 349  GLU A N   1 
ATOM   2598  C CA  . GLU A 1 370 ? 88.799  85.966  72.060  1.00 19.61 ? 349  GLU A CA  1 
ATOM   2599  C C   . GLU A 1 370 ? 88.072  86.432  73.313  1.00 19.61 ? 349  GLU A C   1 
ATOM   2600  O O   . GLU A 1 370 ? 87.256  85.695  73.881  1.00 19.61 ? 349  GLU A O   1 
ATOM   2601  C CB  . GLU A 1 370 ? 90.196  85.461  72.404  1.00 19.61 ? 349  GLU A CB  1 
ATOM   2602  C CG  . GLU A 1 370 ? 90.998  85.030  71.192  1.00 19.61 ? 349  GLU A CG  1 
ATOM   2603  C CD  . GLU A 1 370 ? 92.410  84.612  71.541  1.00 19.61 ? 349  GLU A CD  1 
ATOM   2604  O OE1 . GLU A 1 370 ? 92.781  84.696  72.729  1.00 19.61 ? 349  GLU A OE1 1 
ATOM   2605  O OE2 . GLU A 1 370 ? 93.152  84.205  70.624  1.00 19.61 ? 349  GLU A OE2 1 
ATOM   2606  N N   . GLN A 1 371 ? 88.338  87.660  73.752  1.00 17.14 ? 350  GLN A N   1 
ATOM   2607  C CA  . GLN A 1 371 ? 87.609  88.177  74.900  1.00 17.14 ? 350  GLN A CA  1 
ATOM   2608  C C   . GLN A 1 371 ? 86.134  88.366  74.575  1.00 17.14 ? 350  GLN A C   1 
ATOM   2609  O O   . GLN A 1 371 ? 85.272  88.100  75.417  1.00 17.14 ? 350  GLN A O   1 
ATOM   2610  C CB  . GLN A 1 371 ? 88.222  89.488  75.377  1.00 17.14 ? 350  GLN A CB  1 
ATOM   2611  C CG  . GLN A 1 371 ? 87.923  89.768  76.828  1.00 17.14 ? 350  GLN A CG  1 
ATOM   2612  C CD  . GLN A 1 371 ? 87.909  91.237  77.138  1.00 17.14 ? 350  GLN A CD  1 
ATOM   2613  O OE1 . GLN A 1 371 ? 87.960  92.069  76.239  1.00 17.14 ? 350  GLN A OE1 1 
ATOM   2614  N NE2 . GLN A 1 371 ? 87.815  91.570  78.415  1.00 17.14 ? 350  GLN A NE2 1 
ATOM   2615  N N   . LYS A 1 372 ? 85.819  88.822  73.363  1.00 18.74 ? 351  LYS A N   1 
ATOM   2616  C CA  . LYS A 1 372 ? 84.418  88.941  72.973  1.00 18.74 ? 351  LYS A CA  1 
ATOM   2617  C C   . LYS A 1 372 ? 83.721  87.591  73.059  1.00 18.74 ? 351  LYS A C   1 
ATOM   2618  O O   . LYS A 1 372 ? 82.595  87.492  73.561  1.00 18.74 ? 351  LYS A O   1 
ATOM   2619  C CB  . LYS A 1 372 ? 84.314  89.515  71.562  1.00 18.74 ? 351  LYS A CB  1 
ATOM   2620  C CG  . LYS A 1 372 ? 82.904  89.573  71.008  1.00 18.74 ? 351  LYS A CG  1 
ATOM   2621  C CD  . LYS A 1 372 ? 82.909  89.324  69.510  1.00 18.74 ? 351  LYS A CD  1 
ATOM   2622  C CE  . LYS A 1 372 ? 81.527  89.496  68.916  1.00 18.74 ? 351  LYS A CE  1 
ATOM   2623  N NZ  . LYS A 1 372 ? 81.010  90.869  69.141  1.00 18.74 ? 351  LYS A NZ  1 
ATOM   2624  N N   . GLU A 1 373 ? 84.396  86.534  72.606  1.00 21.78 ? 352  GLU A N   1 
ATOM   2625  C CA  . GLU A 1 373 ? 83.841  85.192  72.736  1.00 21.78 ? 352  GLU A CA  1 
ATOM   2626  C C   . GLU A 1 373 ? 83.671  84.800  74.199  1.00 21.78 ? 352  GLU A C   1 
ATOM   2627  O O   . GLU A 1 373 ? 82.692  84.140  74.560  1.00 21.78 ? 352  GLU A O   1 
ATOM   2628  C CB  . GLU A 1 373 ? 84.732  84.189  72.005  1.00 21.78 ? 352  GLU A CB  1 
ATOM   2629  C CG  . GLU A 1 373 ? 84.839  84.444  70.508  1.00 21.78 ? 352  GLU A CG  1 
ATOM   2630  C CD  . GLU A 1 373 ? 86.028  83.745  69.871  1.00 21.78 ? 352  GLU A CD  1 
ATOM   2631  O OE1 . GLU A 1 373 ? 86.756  84.399  69.096  1.00 21.78 ? 352  GLU A OE1 1 
ATOM   2632  O OE2 . GLU A 1 373 ? 86.234  82.544  70.145  1.00 21.78 ? 352  GLU A OE2 1 
ATOM   2633  N N   . LYS A 1 374 ? 84.620  85.186  75.056  1.00 18.86 ? 353  LYS A N   1 
ATOM   2634  C CA  . LYS A 1 374 ? 84.519  84.839  76.472  1.00 18.86 ? 353  LYS A CA  1 
ATOM   2635  C C   . LYS A 1 374 ? 83.302  85.486  77.124  1.00 18.86 ? 353  LYS A C   1 
ATOM   2636  O O   . LYS A 1 374 ? 82.542  84.822  77.840  1.00 18.86 ? 353  LYS A O   1 
ATOM   2637  C CB  . LYS A 1 374 ? 85.798  85.236  77.207  1.00 18.86 ? 353  LYS A CB  1 
ATOM   2638  C CG  . LYS A 1 374 ? 87.005  84.419  76.800  1.00 18.86 ? 353  LYS A CG  1 
ATOM   2639  C CD  . LYS A 1 374 ? 88.205  84.681  77.688  1.00 18.86 ? 353  LYS A CD  1 
ATOM   2640  C CE  . LYS A 1 374 ? 89.497  84.457  76.912  1.00 18.86 ? 353  LYS A CE  1 
ATOM   2641  N NZ  . LYS A 1 374 ? 90.464  83.597  77.646  1.00 18.86 ? 353  LYS A NZ  1 
ATOM   2642  N N   . ILE A 1 375 ? 83.097  86.786  76.894  1.00 17.98 ? 354  ILE A N   1 
ATOM   2643  C CA  . ILE A 1 375 ? 81.907  87.428  77.457  1.00 17.98 ? 354  ILE A CA  1 
ATOM   2644  C C   . ILE A 1 375 ? 80.633  86.872  76.834  1.00 17.98 ? 354  ILE A C   1 
ATOM   2645  O O   . ILE A 1 375 ? 79.616  86.736  77.518  1.00 17.98 ? 354  ILE A O   1 
ATOM   2646  C CB  . ILE A 1 375 ? 81.956  88.969  77.374  1.00 17.98 ? 354  ILE A CB  1 
ATOM   2647  C CG1 . ILE A 1 375 ? 83.093  89.562  78.212  1.00 17.98 ? 354  ILE A CG1 1 
ATOM   2648  C CG2 . ILE A 1 375 ? 80.645  89.579  77.818  1.00 17.98 ? 354  ILE A CG2 1 
ATOM   2649  C CD1 . ILE A 1 375 ? 84.388  89.720  77.562  1.00 17.98 ? 354  ILE A CD1 1 
ATOM   2650  N N   . LEU A 1 376 ? 80.652  86.529  75.544  1.00 18.25 ? 355  LEU A N   1 
ATOM   2651  C CA  . LEU A 1 376 ? 79.459  85.918  74.962  1.00 18.25 ? 355  LEU A CA  1 
ATOM   2652  C C   . LEU A 1 376 ? 79.136  84.589  75.638  1.00 18.25 ? 355  LEU A C   1 
ATOM   2653  O O   . LEU A 1 376 ? 77.972  84.304  75.951  1.00 18.25 ? 355  LEU A O   1 
ATOM   2654  C CB  . LEU A 1 376 ? 79.640  85.730  73.459  1.00 18.25 ? 355  LEU A CB  1 
ATOM   2655  C CG  . LEU A 1 376 ? 79.518  87.010  72.636  1.00 18.25 ? 355  LEU A CG  1 
ATOM   2656  C CD1 . LEU A 1 376 ? 79.983  86.776  71.213  1.00 18.25 ? 355  LEU A CD1 1 
ATOM   2657  C CD2 . LEU A 1 376 ? 78.092  87.516  72.659  1.00 18.25 ? 355  LEU A CD2 1 
ATOM   2658  N N   . SER A 1 377 ? 80.159  83.770  75.888  1.00 19.32 ? 356  SER A N   1 
ATOM   2659  C CA  . SER A 1 377 ? 79.939  82.498  76.565  1.00 19.32 ? 356  SER A CA  1 
ATOM   2660  C C   . SER A 1 377 ? 79.423  82.710  77.981  1.00 19.32 ? 356  SER A C   1 
ATOM   2661  O O   . SER A 1 377 ? 78.566  81.959  78.453  1.00 19.32 ? 356  SER A O   1 
ATOM   2662  C CB  . SER A 1 377 ? 81.226  81.676  76.582  1.00 19.32 ? 356  SER A CB  1 
ATOM   2663  O OG  . SER A 1 377 ? 82.073  82.075  77.643  1.00 19.32 ? 356  SER A OG  1 
ATOM   2664  N N   . TYR A 1 378 ? 79.937  83.724  78.680  1.00 21.34 ? 357  TYR A N   1 
ATOM   2665  C CA  . TYR A 1 378 ? 79.450  83.984  80.032  1.00 21.34 ? 357  TYR A CA  1 
ATOM   2666  C C   . TYR A 1 378 ? 78.026  84.525  80.029  1.00 21.34 ? 357  TYR A C   1 
ATOM   2667  O O   . TYR A 1 378 ? 77.253  84.232  80.946  1.00 21.34 ? 357  TYR A O   1 
ATOM   2668  C CB  . TYR A 1 378 ? 80.387  84.941  80.758  1.00 21.34 ? 357  TYR A CB  1 
ATOM   2669  C CG  . TYR A 1 378 ? 81.381  84.226  81.633  1.00 21.34 ? 357  TYR A CG  1 
ATOM   2670  C CD1 . TYR A 1 378 ? 80.970  83.579  82.787  1.00 21.34 ? 357  TYR A CD1 1 
ATOM   2671  C CD2 . TYR A 1 378 ? 82.726  84.178  81.297  1.00 21.34 ? 357  TYR A CD2 1 
ATOM   2672  C CE1 . TYR A 1 378 ? 81.869  82.915  83.592  1.00 21.34 ? 357  TYR A CE1 1 
ATOM   2673  C CE2 . TYR A 1 378 ? 83.636  83.518  82.096  1.00 21.34 ? 357  TYR A CE2 1 
ATOM   2674  C CZ  . TYR A 1 378 ? 83.202  82.889  83.245  1.00 21.34 ? 357  TYR A CZ  1 
ATOM   2675  O OH  . TYR A 1 378 ? 84.100  82.227  84.049  1.00 21.34 ? 357  TYR A OH  1 
ATOM   2676  N N   . LEU A 1 379 ? 77.656  85.298  79.008  1.00 17.75 ? 358  LEU A N   1 
ATOM   2677  C CA  . LEU A 1 379 ? 76.262  85.700  78.855  1.00 17.75 ? 358  LEU A CA  1 
ATOM   2678  C C   . LEU A 1 379 ? 75.373  84.485  78.648  1.00 17.75 ? 358  LEU A C   1 
ATOM   2679  O O   . LEU A 1 379 ? 74.283  84.396  79.225  1.00 17.75 ? 358  LEU A O   1 
ATOM   2680  C CB  . LEU A 1 379 ? 76.108  86.668  77.682  1.00 17.75 ? 358  LEU A CB  1 
ATOM   2681  C CG  . LEU A 1 379 ? 76.804  88.027  77.747  1.00 17.75 ? 358  LEU A CG  1 
ATOM   2682  C CD1 . LEU A 1 379 ? 76.913  88.630  76.364  1.00 17.75 ? 358  LEU A CD1 1 
ATOM   2683  C CD2 . LEU A 1 379 ? 76.057  88.953  78.655  1.00 17.75 ? 358  LEU A CD2 1 
ATOM   2684  N N   . ASP A 1 380 ? 75.825  83.535  77.826  1.00 22.33 ? 359  ASP A N   1 
ATOM   2685  C CA  . ASP A 1 380 ? 75.031  82.332  77.597  1.00 22.33 ? 359  ASP A CA  1 
ATOM   2686  C C   . ASP A 1 380 ? 74.932  81.485  78.859  1.00 22.33 ? 359  ASP A C   1 
ATOM   2687  O O   . ASP A 1 380 ? 73.879  80.904  79.138  1.00 22.33 ? 359  ASP A O   1 
ATOM   2688  C CB  . ASP A 1 380 ? 75.620  81.525  76.446  1.00 22.33 ? 359  ASP A CB  1 
ATOM   2689  C CG  . ASP A 1 380 ? 75.101  81.980  75.102  1.00 22.33 ? 359  ASP A CG  1 
ATOM   2690  O OD1 . ASP A 1 380 ? 73.884  81.847  74.860  1.00 22.33 ? 359  ASP A OD1 1 
ATOM   2691  O OD2 . ASP A 1 380 ? 75.907  82.479  74.290  1.00 22.33 ? 359  ASP A OD2 1 
ATOM   2692  N N   . ILE A 1 381 ? 76.015  81.409  79.633  1.00 21.97 ? 360  ILE A N   1 
ATOM   2693  C CA  . ILE A 1 381 ? 75.985  80.698  80.910  1.00 21.97 ? 360  ILE A CA  1 
ATOM   2694  C C   . ILE A 1 381 ? 74.985  81.345  81.856  1.00 21.97 ? 360  ILE A C   1 
ATOM   2695  O O   . ILE A 1 381 ? 74.197  80.658  82.517  1.00 21.97 ? 360  ILE A O   1 
ATOM   2696  C CB  . ILE A 1 381 ? 77.394  80.656  81.528  1.00 21.97 ? 360  ILE A CB  1 
ATOM   2697  C CG1 . ILE A 1 381 ? 78.302  79.719  80.737  1.00 21.97 ? 360  ILE A CG1 1 
ATOM   2698  C CG2 . ILE A 1 381 ? 77.328  80.249  82.990  1.00 21.97 ? 360  ILE A CG2 1 
ATOM   2699  C CD1 . ILE A 1 381 ? 79.760  79.850  81.097  1.00 21.97 ? 360  ILE A CD1 1 
ATOM   2700  N N   . GLY A 1 382 ? 75.001  82.676  81.940  1.00 19.80 ? 361  GLY A N   1 
ATOM   2701  C CA  . GLY A 1 382 ? 74.053  83.362  82.801  1.00 19.80 ? 361  GLY A CA  1 
ATOM   2702  C C   . GLY A 1 382 ? 72.616  83.161  82.363  1.00 19.80 ? 361  GLY A C   1 
ATOM   2703  O O   . GLY A 1 382 ? 71.723  82.987  83.195  1.00 19.80 ? 361  GLY A O   1 
ATOM   2704  N N   . LYS A 1 383 ? 72.374  83.190  81.051  1.00 21.57 ? 362  LYS A N   1 
ATOM   2705  C CA  . LYS A 1 383 ? 71.035  82.922  80.536  1.00 21.57 ? 362  LYS A CA  1 
ATOM   2706  C C   . LYS A 1 383 ? 70.594  81.500  80.858  1.00 21.57 ? 362  LYS A C   1 
ATOM   2707  O O   . LYS A 1 383 ? 69.440  81.268  81.234  1.00 21.57 ? 362  LYS A O   1 
ATOM   2708  C CB  . LYS A 1 383 ? 70.998  83.165  79.029  1.00 21.57 ? 362  LYS A CB  1 
ATOM   2709  C CG  . LYS A 1 383 ? 70.835  84.618  78.634  1.00 21.57 ? 362  LYS A CG  1 
ATOM   2710  C CD  . LYS A 1 383 ? 71.533  84.903  77.318  1.00 21.57 ? 362  LYS A CD  1 
ATOM   2711  C CE  . LYS A 1 383 ? 71.238  86.307  76.830  1.00 21.57 ? 362  LYS A CE  1 
ATOM   2712  N NZ  . LYS A 1 383 ? 70.263  86.313  75.708  1.00 21.57 ? 362  LYS A NZ  1 
ATOM   2713  N N   . LYS A 1 384 ? 71.501  80.532  80.710  1.00 25.62 ? 363  LYS A N   1 
ATOM   2714  C CA  . LYS A 1 384 ? 71.178  79.139  80.984  1.00 25.62 ? 363  LYS A CA  1 
ATOM   2715  C C   . LYS A 1 384 ? 71.062  78.845  82.472  1.00 25.62 ? 363  LYS A C   1 
ATOM   2716  O O   . LYS A 1 384 ? 70.527  77.795  82.839  1.00 25.62 ? 363  LYS A O   1 
ATOM   2717  C CB  . LYS A 1 384 ? 72.239  78.227  80.369  1.00 25.62 ? 363  LYS A CB  1 
ATOM   2718  C CG  . LYS A 1 384 ? 72.150  78.091  78.862  1.00 25.62 ? 363  LYS A CG  1 
ATOM   2719  C CD  . LYS A 1 384 ? 73.305  77.268  78.320  1.00 25.62 ? 363  LYS A CD  1 
ATOM   2720  C CE  . LYS A 1 384 ? 73.225  77.129  76.811  1.00 25.62 ? 363  LYS A CE  1 
ATOM   2721  N NZ  . LYS A 1 384 ? 73.345  78.444  76.127  1.00 25.62 ? 363  LYS A NZ  1 
ATOM   2722  N N   . GLU A 1 385 ? 71.555  79.735  83.332  1.00 27.42 ? 364  GLU A N   1 
ATOM   2723  C CA  . GLU A 1 385 ? 71.528  79.520  84.772  1.00 27.42 ? 364  GLU A CA  1 
ATOM   2724  C C   . GLU A 1 385 ? 70.333  80.180  85.451  1.00 27.42 ? 364  GLU A C   1 
ATOM   2725  O O   . GLU A 1 385 ? 70.298  80.256  86.683  1.00 27.42 ? 364  GLU A O   1 
ATOM   2726  C CB  . GLU A 1 385 ? 72.828  80.018  85.405  1.00 27.42 ? 364  GLU A CB  1 
ATOM   2727  C CG  . GLU A 1 385 ? 73.260  79.220  86.624  1.00 27.42 ? 364  GLU A CG  1 
ATOM   2728  C CD  . GLU A 1 385 ? 74.649  79.575  87.093  1.00 27.42 ? 364  GLU A CD  1 
ATOM   2729  O OE1 . GLU A 1 385 ? 75.214  78.808  87.898  1.00 27.42 ? 364  GLU A OE1 1 
ATOM   2730  O OE2 . GLU A 1 385 ? 75.174  80.621  86.661  1.00 27.42 ? 364  GLU A OE2 1 
ATOM   2731  N N   . GLY A 1 386 ? 69.361  80.661  84.684  1.00 24.57 ? 365  GLY A N   1 
ATOM   2732  C CA  . GLY A 1 386 ? 68.158  81.216  85.274  1.00 24.57 ? 365  GLY A CA  1 
ATOM   2733  C C   . GLY A 1 386 ? 68.294  82.616  85.828  1.00 24.57 ? 365  GLY A C   1 
ATOM   2734  O O   . GLY A 1 386 ? 67.791  82.896  86.923  1.00 24.57 ? 365  GLY A O   1 
ATOM   2735  N N   . ALA A 1 387 ? 68.961  83.509  85.102  1.00 19.71 ? 366  ALA A N   1 
ATOM   2736  C CA  . ALA A 1 387 ? 69.095  84.908  85.486  1.00 19.71 ? 366  ALA A CA  1 
ATOM   2737  C C   . ALA A 1 387 ? 68.549  85.766  84.357  1.00 19.71 ? 366  ALA A C   1 
ATOM   2738  O O   . ALA A 1 387 ? 69.024  85.671  83.221  1.00 19.71 ? 366  ALA A O   1 
ATOM   2739  C CB  . ALA A 1 387 ? 70.554  85.265  85.775  1.00 19.71 ? 366  ALA A CB  1 
ATOM   2740  N N   . GLU A 1 388 ? 67.560  86.599  84.666  1.00 16.97 ? 367  GLU A N   1 
ATOM   2741  C CA  . GLU A 1 388 ? 66.927  87.401  83.632  1.00 16.97 ? 367  GLU A CA  1 
ATOM   2742  C C   . GLU A 1 388 ? 67.867  88.501  83.153  1.00 16.97 ? 367  GLU A C   1 
ATOM   2743  O O   . GLU A 1 388 ? 68.762  88.950  83.871  1.00 16.97 ? 367  GLU A O   1 
ATOM   2744  C CB  . GLU A 1 388 ? 65.621  88.010  84.140  1.00 16.97 ? 367  GLU A CB  1 
ATOM   2745  C CG  . GLU A 1 388 ? 65.795  89.038  85.238  1.00 16.97 ? 367  GLU A CG  1 
ATOM   2746  C CD  . GLU A 1 388 ? 64.594  89.955  85.371  1.00 16.97 ? 367  GLU A CD  1 
ATOM   2747  O OE1 . GLU A 1 388 ? 63.716  89.919  84.484  1.00 16.97 ? 367  GLU A OE1 1 
ATOM   2748  O OE2 . GLU A 1 388 ? 64.523  90.709  86.365  1.00 16.97 ? 367  GLU A OE2 1 
ATOM   2749  N N   . VAL A 1 389 ? 67.654  88.934  81.915  1.00 12.81 ? 368  VAL A N   1 
ATOM   2750  C CA  . VAL A 1 389 ? 68.462  89.973  81.290  1.00 12.81 ? 368  VAL A CA  1 
ATOM   2751  C C   . VAL A 1 389 ? 67.630  91.245  81.234  1.00 12.81 ? 368  VAL A C   1 
ATOM   2752  O O   . VAL A 1 389 ? 66.577  91.277  80.586  1.00 12.81 ? 368  VAL A O   1 
ATOM   2753  C CB  . VAL A 1 389 ? 68.930  89.558  79.889  1.00 12.81 ? 368  VAL A CB  1 
ATOM   2754  C CG1 . VAL A 1 389 ? 69.780  90.644  79.282  1.00 12.81 ? 368  VAL A CG1 1 
ATOM   2755  C CG2 . VAL A 1 389 ? 69.696  88.257  79.954  1.00 12.81 ? 368  VAL A CG2 1 
ATOM   2756  N N   . LEU A 1 390 ? 68.101  92.293  81.907  1.00 12.02 ? 369  LEU A N   1 
ATOM   2757  C CA  . LEU A 1 390 ? 67.364  93.549  81.964  1.00 12.02 ? 369  LEU A CA  1 
ATOM   2758  C C   . LEU A 1 390 ? 67.670  94.462  80.788  1.00 12.02 ? 369  LEU A C   1 
ATOM   2759  O O   . LEU A 1 390 ? 66.798  95.229  80.364  1.00 12.02 ? 369  LEU A O   1 
ATOM   2760  C CB  . LEU A 1 390 ? 67.670  94.279  83.271  1.00 12.02 ? 369  LEU A CB  1 
ATOM   2761  C CG  . LEU A 1 390 ? 66.736  93.961  84.438  1.00 12.02 ? 369  LEU A CG  1 
ATOM   2762  C CD1 . LEU A 1 390 ? 66.871  92.511  84.843  1.00 12.02 ? 369  LEU A CD1 1 
ATOM   2763  C CD2 . LEU A 1 390 ? 67.017  94.869  85.619  1.00 12.02 ? 369  LEU A CD2 1 
ATOM   2764  N N   . THR A 1 391 ? 68.887  94.403  80.260  1.00 12.01 ? 370  THR A N   1 
ATOM   2765  C CA  . THR A 1 391 ? 69.241  95.101  79.036  1.00 12.01 ? 370  THR A CA  1 
ATOM   2766  C C   . THR A 1 391 ? 70.460  94.416  78.449  1.00 12.01 ? 370  THR A C   1 
ATOM   2767  O O   . THR A 1 391 ? 71.201  93.728  79.156  1.00 12.01 ? 370  THR A O   1 
ATOM   2768  C CB  . THR A 1 391 ? 69.521  96.587  79.278  1.00 12.01 ? 370  THR A CB  1 
ATOM   2769  O OG1 . THR A 1 391 ? 69.697  97.251  78.020  1.00 12.01 ? 370  THR A OG1 1 
ATOM   2770  C CG2 . THR A 1 391 ? 70.770  96.767  80.111  1.00 12.01 ? 370  THR A CG2 1 
ATOM   2771  N N   . GLY A 1 392 ? 70.665  94.623  77.152  1.00 11.25 ? 371  GLY A N   1 
ATOM   2772  C CA  . GLY A 1 392 ? 71.784  93.995  76.487  1.00 11.25 ? 371  GLY A CA  1 
ATOM   2773  C C   . GLY A 1 392 ? 71.616  92.486  76.442  1.00 11.25 ? 371  GLY A C   1 
ATOM   2774  O O   . GLY A 1 392 ? 70.514  91.944  76.544  1.00 11.25 ? 371  GLY A O   1 
ATOM   2775  N N   . GLY A 1 393 ? 72.742  91.802  76.276  1.00 16.57 ? 372  GLY A N   1 
ATOM   2776  C CA  . GLY A 1 393 ? 72.737  90.355  76.323  1.00 16.57 ? 372  GLY A CA  1 
ATOM   2777  C C   . GLY A 1 393 ? 73.408  89.691  75.141  1.00 16.57 ? 372  GLY A C   1 
ATOM   2778  O O   . GLY A 1 393 ? 73.520  88.463  75.100  1.00 16.57 ? 372  GLY A O   1 
ATOM   2779  N N   . LYS A 1 394 ? 73.864  90.480  74.174  1.00 18.72 ? 373  LYS A N   1 
ATOM   2780  C CA  . LYS A 1 394 ? 74.464  89.920  72.974  1.00 18.72 ? 373  LYS A CA  1 
ATOM   2781  C C   . LYS A 1 394 ? 75.509  90.894  72.449  1.00 18.72 ? 373  LYS A C   1 
ATOM   2782  O O   . LYS A 1 394 ? 75.834  91.893  73.095  1.00 18.72 ? 373  LYS A O   1 
ATOM   2783  C CB  . LYS A 1 394 ? 73.385  89.622  71.927  1.00 18.72 ? 373  LYS A CB  1 
ATOM   2784  C CG  . LYS A 1 394 ? 72.697  90.867  71.406  1.00 18.72 ? 373  LYS A CG  1 
ATOM   2785  C CD  . LYS A 1 394 ? 71.668  90.529  70.356  1.00 18.72 ? 373  LYS A CD  1 
ATOM   2786  C CE  . LYS A 1 394 ? 70.469  89.869  71.009  1.00 18.72 ? 373  LYS A CE  1 
ATOM   2787  N NZ  . LYS A 1 394 ? 69.759  90.824  71.907  1.00 18.72 ? 373  LYS A NZ  1 
ATOM   2788  N N   . ALA A 1 395 ? 76.034  90.599  71.265  1.00 17.93 ? 374  ALA A N   1 
ATOM   2789  C CA  . ALA A 1 395 ? 76.998  91.467  70.609  1.00 17.93 ? 374  ALA A CA  1 
ATOM   2790  C C   . ALA A 1 395 ? 76.260  92.641  69.975  1.00 17.93 ? 374  ALA A C   1 
ATOM   2791  O O   . ALA A 1 395 ? 75.059  92.836  70.181  1.00 17.93 ? 374  ALA A O   1 
ATOM   2792  C CB  . ALA A 1 395 ? 77.808  90.676  69.588  1.00 17.93 ? 374  ALA A CB  1 
ATOM   2793  N N   . ALA A 1 396 ? 76.971  93.447  69.193  1.00 20.49 ? 375  ALA A N   1 
ATOM   2794  C CA  . ALA A 1 396 ? 76.353  94.588  68.535  1.00 20.49 ? 375  ALA A CA  1 
ATOM   2795  C C   . ALA A 1 396 ? 77.075  94.866  67.229  1.00 20.49 ? 375  ALA A C   1 
ATOM   2796  O O   . ALA A 1 396 ? 78.308  94.901  67.195  1.00 20.49 ? 375  ALA A O   1 
ATOM   2797  C CB  . ALA A 1 396 ? 76.382  95.829  69.430  1.00 20.49 ? 375  ALA A CB  1 
ATOM   2798  N N   . ASP A 1 397 ? 76.305  95.057  66.162  1.00 26.31 ? 376  ASP A N   1 
ATOM   2799  C CA  . ASP A 1 397 ? 76.837  95.479  64.869  1.00 26.31 ? 376  ASP A CA  1 
ATOM   2800  C C   . ASP A 1 397 ? 76.512  96.958  64.715  1.00 26.31 ? 376  ASP A C   1 
ATOM   2801  O O   . ASP A 1 397 ? 75.371  97.330  64.433  1.00 26.31 ? 376  ASP A O   1 
ATOM   2802  C CB  . ASP A 1 397 ? 76.248  94.653  63.731  1.00 26.31 ? 376  ASP A CB  1 
ATOM   2803  C CG  . ASP A 1 397 ? 76.479  95.288  62.371  1.00 26.31 ? 376  ASP A CG  1 
ATOM   2804  O OD1 . ASP A 1 397 ? 77.590  95.808  62.134  1.00 26.31 ? 376  ASP A OD1 1 
ATOM   2805  O OD2 . ASP A 1 397 ? 75.546  95.271  61.540  1.00 26.31 ? 376  ASP A OD2 1 
ATOM   2806  N N   . LEU A 1 398 ? 77.520  97.803  64.898  1.00 24.60 ? 377  LEU A N   1 
ATOM   2807  C CA  . LEU A 1 398 ? 77.325  99.243  64.868  1.00 24.60 ? 377  LEU A CA  1 
ATOM   2808  C C   . LEU A 1 398 ? 77.350  99.818  63.457  1.00 24.60 ? 377  LEU A C   1 
ATOM   2809  O O   . LEU A 1 398 ? 77.520  101.033 63.297  1.00 24.60 ? 377  LEU A O   1 
ATOM   2810  C CB  . LEU A 1 398 ? 78.379  99.928  65.741  1.00 24.60 ? 377  LEU A CB  1 
ATOM   2811  C CG  . LEU A 1 398 ? 78.381  99.514  67.213  1.00 24.60 ? 377  LEU A CG  1 
ATOM   2812  C CD1 . LEU A 1 398 ? 79.202  100.481 68.031  1.00 24.60 ? 377  LEU A CD1 1 
ATOM   2813  C CD2 . LEU A 1 398 ? 76.967  99.430  67.752  1.00 24.60 ? 377  LEU A CD2 1 
ATOM   2814  N N   . GLY A 1 399 ? 77.185  98.981  62.437  1.00 23.74 ? 378  GLY A N   1 
ATOM   2815  C CA  . GLY A 1 399 ? 77.107  99.459  61.073  1.00 23.74 ? 378  GLY A CA  1 
ATOM   2816  C C   . GLY A 1 399 ? 78.423  99.961  60.519  1.00 23.74 ? 378  GLY A C   1 
ATOM   2817  O O   . GLY A 1 399 ? 79.329  100.322 61.274  1.00 23.74 ? 378  GLY A O   1 
ATOM   2818  N N   . GLY A 1 400 ? 78.535  99.993  59.196  1.00 21.62 ? 379  GLY A N   1 
ATOM   2819  C CA  . GLY A 1 400 ? 79.749  100.468 58.573  1.00 21.62 ? 379  GLY A CA  1 
ATOM   2820  C C   . GLY A 1 400 ? 80.926  99.566  58.884  1.00 21.62 ? 379  GLY A C   1 
ATOM   2821  O O   . GLY A 1 400 ? 80.794  98.351  59.067  1.00 21.62 ? 379  GLY A O   1 
ATOM   2822  N N   . GLU A 1 401 ? 82.107  100.180 58.954  1.00 23.35 ? 380  GLU A N   1 
ATOM   2823  C CA  . GLU A 1 401 ? 83.332  99.443  59.233  1.00 23.35 ? 380  GLU A CA  1 
ATOM   2824  C C   . GLU A 1 401 ? 83.364  98.872  60.641  1.00 23.35 ? 380  GLU A C   1 
ATOM   2825  O O   . GLU A 1 401 ? 84.197  98.004  60.921  1.00 23.35 ? 380  GLU A O   1 
ATOM   2826  C CB  . GLU A 1 401 ? 84.540  100.351 59.010  1.00 23.35 ? 380  GLU A CB  1 
ATOM   2827  C CG  . GLU A 1 401 ? 84.407  101.243 57.790  1.00 23.35 ? 380  GLU A CG  1 
ATOM   2828  C CD  . GLU A 1 401 ? 85.492  102.293 57.717  1.00 23.35 ? 380  GLU A CD  1 
ATOM   2829  O OE1 . GLU A 1 401 ? 86.390  102.278 58.583  1.00 23.35 ? 380  GLU A OE1 1 
ATOM   2830  O OE2 . GLU A 1 401 ? 85.445  103.135 56.796  1.00 23.35 ? 380  GLU A OE2 1 
ATOM   2831  N N   . LEU A 1 402 ? 82.468  99.320  61.521  1.00 19.65 ? 381  LEU A N   1 
ATOM   2832  C CA  . LEU A 1 402 ? 82.426  98.842  62.895  1.00 19.65 ? 381  LEU A CA  1 
ATOM   2833  C C   . LEU A 1 402 ? 81.928  97.409  63.009  1.00 19.65 ? 381  LEU A C   1 
ATOM   2834  O O   . LEU A 1 402 ? 81.984  96.842  64.104  1.00 19.65 ? 381  LEU A O   1 
ATOM   2835  C CB  . LEU A 1 402 ? 81.545  99.762  63.738  1.00 19.65 ? 381  LEU A CB  1 
ATOM   2836  C CG  . LEU A 1 402 ? 81.818  101.265 63.639  1.00 19.65 ? 381  LEU A CG  1 
ATOM   2837  C CD1 . LEU A 1 402 ? 81.077  102.017 64.723  1.00 19.65 ? 381  LEU A CD1 1 
ATOM   2838  C CD2 . LEU A 1 402 ? 83.298  101.557 63.725  1.00 19.65 ? 381  LEU A CD2 1 
ATOM   2839  N N   . SER A 1 403 ? 81.436  96.816  61.918  1.00 20.98 ? 382  SER A N   1 
ATOM   2840  C CA  . SER A 1 403 ? 80.959  95.438  61.970  1.00 20.98 ? 382  SER A CA  1 
ATOM   2841  C C   . SER A 1 403 ? 82.074  94.487  62.380  1.00 20.98 ? 382  SER A C   1 
ATOM   2842  O O   . SER A 1 403 ? 81.874  93.602  63.219  1.00 20.98 ? 382  SER A O   1 
ATOM   2843  C CB  . SER A 1 403 ? 80.381  95.031  60.617  1.00 20.98 ? 382  SER A CB  1 
ATOM   2844  O OG  . SER A 1 403 ? 81.399  94.949  59.636  1.00 20.98 ? 382  SER A OG  1 
ATOM   2845  N N   . GLY A 1 404 ? 83.262  94.657  61.798  1.00 19.52 ? 383  GLY A N   1 
ATOM   2846  C CA  . GLY A 1 404 ? 84.393  93.823  62.159  1.00 19.52 ? 383  GLY A CA  1 
ATOM   2847  C C   . GLY A 1 404 ? 84.836  93.984  63.597  1.00 19.52 ? 383  GLY A C   1 
ATOM   2848  O O   . GLY A 1 404 ? 85.506  93.097  64.133  1.00 19.52 ? 383  GLY A O   1 
ATOM   2849  N N   . GLY A 1 405 ? 84.473  95.089  64.236  1.00 17.22 ? 384  GLY A N   1 
ATOM   2850  C CA  . GLY A 1 405 ? 84.854  95.315  65.612  1.00 17.22 ? 384  GLY A CA  1 
ATOM   2851  C C   . GLY A 1 405 ? 84.084  94.440  66.580  1.00 17.22 ? 384  GLY A C   1 
ATOM   2852  O O   . GLY A 1 405 ? 83.096  93.787  66.243  1.00 17.22 ? 384  GLY A O   1 
ATOM   2853  N N   . TYR A 1 406 ? 84.552  94.437  67.821  1.00 16.18 ? 385  TYR A N   1 
ATOM   2854  C CA  . TYR A 1 406 ? 84.057  93.539  68.859  1.00 16.18 ? 385  TYR A CA  1 
ATOM   2855  C C   . TYR A 1 406 ? 83.356  94.380  69.919  1.00 16.18 ? 385  TYR A C   1 
ATOM   2856  O O   . TYR A 1 406 ? 83.986  94.895  70.842  1.00 16.18 ? 385  TYR A O   1 
ATOM   2857  C CB  . TYR A 1 406 ? 85.202  92.732  69.441  1.00 16.18 ? 385  TYR A CB  1 
ATOM   2858  C CG  . TYR A 1 406 ? 86.179  92.279  68.387  1.00 16.18 ? 385  TYR A CG  1 
ATOM   2859  C CD1 . TYR A 1 406 ? 85.861  91.250  67.519  1.00 16.18 ? 385  TYR A CD1 1 
ATOM   2860  C CD2 . TYR A 1 406 ? 87.411  92.896  68.246  1.00 16.18 ? 385  TYR A CD2 1 
ATOM   2861  C CE1 . TYR A 1 406 ? 86.744  90.843  66.548  1.00 16.18 ? 385  TYR A CE1 1 
ATOM   2862  C CE2 . TYR A 1 406 ? 88.301  92.493  67.278  1.00 16.18 ? 385  TYR A CE2 1 
ATOM   2863  C CZ  . TYR A 1 406 ? 87.963  91.465  66.433  1.00 16.18 ? 385  TYR A CZ  1 
ATOM   2864  O OH  . TYR A 1 406 ? 88.847  91.057  65.464  1.00 16.18 ? 385  TYR A OH  1 
ATOM   2865  N N   . TYR A 1 407 ? 82.040  94.504  69.787  1.00 13.81 ? 386  TYR A N   1 
ATOM   2866  C CA  . TYR A 1 407 ? 81.231  95.355  70.651  1.00 13.81 ? 386  TYR A CA  1 
ATOM   2867  C C   . TYR A 1 407 ? 80.179  94.495  71.334  1.00 13.81 ? 386  TYR A C   1 
ATOM   2868  O O   . TYR A 1 407 ? 79.300  93.939  70.670  1.00 13.81 ? 386  TYR A O   1 
ATOM   2869  C CB  . TYR A 1 407 ? 80.570  96.481  69.858  1.00 13.81 ? 386  TYR A CB  1 
ATOM   2870  C CG  . TYR A 1 407 ? 81.516  97.327  69.040  1.00 13.81 ? 386  TYR A CG  1 
ATOM   2871  C CD1 . TYR A 1 407 ? 81.988  96.885  67.815  1.00 13.81 ? 386  TYR A CD1 1 
ATOM   2872  C CD2 . TYR A 1 407 ? 81.926  98.573  69.486  1.00 13.81 ? 386  TYR A CD2 1 
ATOM   2873  C CE1 . TYR A 1 407 ? 82.845  97.654  67.066  1.00 13.81 ? 386  TYR A CE1 1 
ATOM   2874  C CE2 . TYR A 1 407 ? 82.784  99.347  68.741  1.00 13.81 ? 386  TYR A CE2 1 
ATOM   2875  C CZ  . TYR A 1 407 ? 83.241  98.881  67.532  1.00 13.81 ? 386  TYR A CZ  1 
ATOM   2876  O OH  . TYR A 1 407 ? 84.095  99.644  66.778  1.00 13.81 ? 386  TYR A OH  1 
ATOM   2877  N N   . ILE A 1 408 ? 80.266  94.393  72.652  1.00 12.52 ? 387  ILE A N   1 
ATOM   2878  C CA  . ILE A 1 408 ? 79.241  93.741  73.455  1.00 12.52 ? 387  ILE A CA  1 
ATOM   2879  C C   . ILE A 1 408 ? 78.299  94.809  73.984  1.00 12.52 ? 387  ILE A C   1 
ATOM   2880  O O   . ILE A 1 408 ? 78.743  95.821  74.536  1.00 12.52 ? 387  ILE A O   1 
ATOM   2881  C CB  . ILE A 1 408 ? 79.869  92.946  74.609  1.00 12.52 ? 387  ILE A CB  1 
ATOM   2882  C CG1 . ILE A 1 408 ? 80.562  91.696  74.079  1.00 12.52 ? 387  ILE A CG1 1 
ATOM   2883  C CG2 . ILE A 1 408 ? 78.814  92.574  75.637  1.00 12.52 ? 387  ILE A CG2 1 
ATOM   2884  C CD1 . ILE A 1 408 ? 79.608  90.626  73.652  1.00 12.52 ? 387  ILE A CD1 1 
ATOM   2885  N N   . GLU A 1 409 ? 77.003  94.595  73.809  1.00 14.51 ? 388  GLU A N   1 
ATOM   2886  C CA  . GLU A 1 409 ? 76.031  95.537  74.337  1.00 14.51 ? 388  GLU A CA  1 
ATOM   2887  C C   . GLU A 1 409 ? 76.071  95.528  75.863  1.00 14.51 ? 388  GLU A C   1 
ATOM   2888  O O   . GLU A 1 409 ? 76.183  94.461  76.472  1.00 14.51 ? 388  GLU A O   1 
ATOM   2889  C CB  . GLU A 1 409 ? 74.628  95.189  73.846  1.00 14.51 ? 388  GLU A CB  1 
ATOM   2890  C CG  . GLU A 1 409 ? 74.375  95.594  72.406  1.00 14.51 ? 388  GLU A CG  1 
ATOM   2891  C CD  . GLU A 1 409 ? 72.970  95.274  71.937  1.00 14.51 ? 388  GLU A CD  1 
ATOM   2892  O OE1 . GLU A 1 409 ? 72.402  96.085  71.176  1.00 14.51 ? 388  GLU A OE1 1 
ATOM   2893  O OE2 . GLU A 1 409 ? 72.436  94.211  72.319  1.00 14.51 ? 388  GLU A OE2 1 
ATOM   2894  N N   . PRO A 1 410 ? 76.004  96.698  76.506  1.00 10.69 ? 389  PRO A N   1 
ATOM   2895  C CA  . PRO A 1 410 ? 75.985  96.733  77.974  1.00 10.69 ? 389  PRO A CA  1 
ATOM   2896  C C   . PRO A 1 410 ? 74.859  95.894  78.550  1.00 10.69 ? 389  PRO A C   1 
ATOM   2897  O O   . PRO A 1 410 ? 73.683  96.217  78.375  1.00 10.69 ? 389  PRO A O   1 
ATOM   2898  C CB  . PRO A 1 410 ? 75.796  98.221  78.286  1.00 10.69 ? 389  PRO A CB  1 
ATOM   2899  C CG  . PRO A 1 410 ? 76.335  98.921  77.106  1.00 10.69 ? 389  PRO A CG  1 
ATOM   2900  C CD  . PRO A 1 410 ? 76.039  98.047  75.923  1.00 10.69 ? 389  PRO A CD  1 
ATOM   2901  N N   . THR A 1 411 ? 75.213  94.821  79.245  1.00 9.29  ? 390  THR A N   1 
ATOM   2902  C CA  . THR A 1 411 ? 74.257  93.825  79.698  1.00 9.29  ? 390  THR A CA  1 
ATOM   2903  C C   . THR A 1 411 ? 74.043  93.938  81.197  1.00 9.29  ? 390  THR A C   1 
ATOM   2904  O O   . THR A 1 411 ? 74.999  94.092  81.959  1.00 9.29  ? 390  THR A O   1 
ATOM   2905  C CB  . THR A 1 411 ? 74.737  92.412  79.369  1.00 9.29  ? 390  THR A CB  1 
ATOM   2906  O OG1 . THR A 1 411 ? 75.003  92.309  77.966  1.00 9.29  ? 390  THR A OG1 1 
ATOM   2907  C CG2 . THR A 1 411 ? 73.685  91.394  79.757  1.00 9.29  ? 390  THR A CG2 1 
ATOM   2908  N N   . ILE A 1 412 ? 72.785  93.856  81.612  1.00 9.14  ? 391  ILE A N   1 
ATOM   2909  C CA  . ILE A 1 412 ? 72.421  93.737  83.018  1.00 9.14  ? 391  ILE A CA  1 
ATOM   2910  C C   . ILE A 1 412 ? 71.775  92.377  83.228  1.00 9.14  ? 391  ILE A C   1 
ATOM   2911  O O   . ILE A 1 412 ? 70.820  92.023  82.528  1.00 9.14  ? 391  ILE A O   1 
ATOM   2912  C CB  . ILE A 1 412 ? 71.474  94.862  83.466  1.00 9.14  ? 391  ILE A CB  1 
ATOM   2913  C CG1 . ILE A 1 412 ? 72.148  96.222  83.344  1.00 9.14  ? 391  ILE A CG1 1 
ATOM   2914  C CG2 . ILE A 1 412 ? 71.046  94.646  84.897  1.00 9.14  ? 391  ILE A CG2 1 
ATOM   2915  C CD1 . ILE A 1 412 ? 71.256  97.365  83.750  1.00 9.14  ? 391  ILE A CD1 1 
ATOM   2916  N N   . PHE A 1 413 ? 72.299  91.613  84.178  1.00 10.55 ? 392  PHE A N   1 
ATOM   2917  C CA  . PHE A 1 413 ? 71.677  90.376  84.610  1.00 10.55 ? 392  PHE A CA  1 
ATOM   2918  C C   . PHE A 1 413 ? 70.936  90.623  85.916  1.00 10.55 ? 392  PHE A C   1 
ATOM   2919  O O   . PHE A 1 413 ? 70.979  91.712  86.488  1.00 10.55 ? 392  PHE A O   1 
ATOM   2920  C CB  . PHE A 1 413 ? 72.718  89.272  84.774  1.00 10.55 ? 392  PHE A CB  1 
ATOM   2921  C CG  . PHE A 1 413 ? 73.170  88.676  83.484  1.00 10.55 ? 392  PHE A CG  1 
ATOM   2922  C CD1 . PHE A 1 413 ? 72.276  88.027  82.658  1.00 10.55 ? 392  PHE A CD1 1 
ATOM   2923  C CD2 . PHE A 1 413 ? 74.489  88.759  83.094  1.00 10.55 ? 392  PHE A CD2 1 
ATOM   2924  C CE1 . PHE A 1 413 ? 72.690  87.477  81.471  1.00 10.55 ? 392  PHE A CE1 1 
ATOM   2925  C CE2 . PHE A 1 413 ? 74.904  88.208  81.904  1.00 10.55 ? 392  PHE A CE2 1 
ATOM   2926  C CZ  . PHE A 1 413 ? 74.003  87.569  81.094  1.00 10.55 ? 392  PHE A CZ  1 
ATOM   2927  N N   . ARG A 1 414 ? 70.248  89.593  86.398  1.00 12.95 ? 393  ARG A N   1 
ATOM   2928  C CA  . ARG A 1 414 ? 69.544  89.699  87.671  1.00 12.95 ? 393  ARG A CA  1 
ATOM   2929  C C   . ARG A 1 414 ? 69.388  88.297  88.237  1.00 12.95 ? 393  ARG A C   1 
ATOM   2930  O O   . ARG A 1 414 ? 68.593  87.507  87.722  1.00 12.95 ? 393  ARG A O   1 
ATOM   2931  C CB  . ARG A 1 414 ? 68.195  90.378  87.490  1.00 12.95 ? 393  ARG A CB  1 
ATOM   2932  C CG  . ARG A 1 414 ? 67.288  90.280  88.692  1.00 12.95 ? 393  ARG A CG  1 
ATOM   2933  C CD  . ARG A 1 414 ? 67.775  91.179  89.804  1.00 12.95 ? 393  ARG A CD  1 
ATOM   2934  N NE  . ARG A 1 414 ? 66.925  91.113  90.987  1.00 12.95 ? 393  ARG A NE  1 
ATOM   2935  C CZ  . ARG A 1 414 ? 67.002  90.161  91.908  1.00 12.95 ? 393  ARG A CZ  1 
ATOM   2936  N NH1 . ARG A 1 414 ? 67.895  89.189  91.786  1.00 12.95 ? 393  ARG A NH1 1 
ATOM   2937  N NH2 . ARG A 1 414 ? 66.190  90.182  92.955  1.00 12.95 ? 393  ARG A NH2 1 
ATOM   2938  N N   . GLY A 1 415 ? 70.143  87.997  89.278  1.00 14.38 ? 394  GLY A N   1 
ATOM   2939  C CA  . GLY A 1 415 ? 70.066  86.713  89.952  1.00 14.38 ? 394  GLY A CA  1 
ATOM   2940  C C   . GLY A 1 415 ? 70.377  86.885  91.416  1.00 14.38 ? 394  GLY A C   1 
ATOM   2941  O O   . GLY A 1 415 ? 70.014  87.895  92.027  1.00 14.38 ? 394  GLY A O   1 
ATOM   2942  N N   . ASN A 1 416 ? 71.049  85.891  91.988  1.00 18.58 ? 395  ASN A N   1 
ATOM   2943  C CA  . ASN A 1 416 ? 71.529  85.960  93.358  1.00 18.58 ? 395  ASN A CA  1 
ATOM   2944  C C   . ASN A 1 416 ? 73.010  85.615  93.380  1.00 18.58 ? 395  ASN A C   1 
ATOM   2945  O O   . ASN A 1 416 ? 73.604  85.255  92.361  1.00 18.58 ? 395  ASN A O   1 
ATOM   2946  C CB  . ASN A 1 416 ? 70.739  85.029  94.288  1.00 18.58 ? 395  ASN A CB  1 
ATOM   2947  C CG  . ASN A 1 416 ? 70.782  83.586  93.842  1.00 18.58 ? 395  ASN A CG  1 
ATOM   2948  O OD1 . ASN A 1 416 ? 71.347  83.260  92.801  1.00 18.58 ? 395  ASN A OD1 1 
ATOM   2949  N ND2 . ASN A 1 416 ? 70.178  82.709  94.632  1.00 18.58 ? 395  ASN A ND2 1 
ATOM   2950  N N   . ASN A 1 417 ? 73.600  85.701  94.569  1.00 19.53 ? 396  ASN A N   1 
ATOM   2951  C CA  . ASN A 1 417 ? 75.046  85.619  94.718  1.00 19.53 ? 396  ASN A CA  1 
ATOM   2952  C C   . ASN A 1 417 ? 75.605  84.236  94.396  1.00 19.53 ? 396  ASN A C   1 
ATOM   2953  O O   . ASN A 1 417 ? 76.823  84.070  94.286  1.00 19.53 ? 396  ASN A O   1 
ATOM   2954  C CB  . ASN A 1 417 ? 75.443  86.022  96.139  1.00 19.53 ? 396  ASN A CB  1 
ATOM   2955  C CG  . ASN A 1 417 ? 76.921  86.295  96.270  1.00 19.53 ? 396  ASN A CG  1 
ATOM   2956  O OD1 . ASN A 1 417 ? 77.516  86.963  95.427  1.00 19.53 ? 396  ASN A OD1 1 
ATOM   2957  N ND2 . ASN A 1 417 ? 77.526  85.775  97.328  1.00 19.53 ? 396  ASN A ND2 1 
ATOM   2958  N N   . LYS A 1 418 ? 74.739  83.237  94.238  1.00 23.53 ? 397  LYS A N   1 
ATOM   2959  C CA  . LYS A 1 418 ? 75.206  81.866  94.091  1.00 23.53 ? 397  LYS A CA  1 
ATOM   2960  C C   . LYS A 1 418 ? 75.383  81.422  92.646  1.00 23.53 ? 397  LYS A C   1 
ATOM   2961  O O   . LYS A 1 418 ? 76.063  80.418  92.411  1.00 23.53 ? 397  LYS A O   1 
ATOM   2962  C CB  . LYS A 1 418 ? 74.249  80.900  94.802  1.00 23.53 ? 397  LYS A CB  1 
ATOM   2963  C CG  . LYS A 1 418 ? 74.165  81.022  96.347  1.00 23.53 ? 397  LYS A CG  1 
ATOM   2964  C CD  . LYS A 1 418 ? 75.469  81.314  97.141  1.00 23.53 ? 397  LYS A CD  1 
ATOM   2965  C CE  . LYS A 1 418 ? 76.727  80.589  96.652  1.00 23.53 ? 397  LYS A CE  1 
ATOM   2966  N NZ  . LYS A 1 418 ? 77.947  81.059  97.360  1.00 23.53 ? 397  LYS A NZ  1 
ATOM   2967  N N   . MET A 1 419 ? 74.804  82.130  91.679  1.00 25.19 ? 398  MET A N   1 
ATOM   2968  C CA  . MET A 1 419 ? 75.004  81.768  90.284  1.00 25.19 ? 398  MET A CA  1 
ATOM   2969  C C   . MET A 1 419 ? 76.452  82.004  89.873  1.00 25.19 ? 398  MET A C   1 
ATOM   2970  O O   . MET A 1 419 ? 77.207  82.723  90.531  1.00 25.19 ? 398  MET A O   1 
ATOM   2971  C CB  . MET A 1 419 ? 74.066  82.556  89.374  1.00 25.19 ? 398  MET A CB  1 
ATOM   2972  C CG  . MET A 1 419 ? 72.680  82.752  89.940  1.00 25.19 ? 398  MET A CG  1 
ATOM   2973  S SD  . MET A 1 419 ? 71.570  83.574  88.789  1.00 25.19 ? 398  MET A SD  1 
ATOM   2974  C CE  . MET A 1 419 ? 69.989  83.046  89.433  1.00 25.19 ? 398  MET A CE  1 
ATOM   2975  N N   . ARG A 1 420 ? 76.839  81.369  88.765  1.00 23.11 ? 399  ARG A N   1 
ATOM   2976  C CA  . ARG A 1 420 ? 78.225  81.439  88.319  1.00 23.11 ? 399  ARG A CA  1 
ATOM   2977  C C   . ARG A 1 420 ? 78.632  82.862  87.968  1.00 23.11 ? 399  ARG A C   1 
ATOM   2978  O O   . ARG A 1 420 ? 79.710  83.319  88.362  1.00 23.11 ? 399  ARG A O   1 
ATOM   2979  C CB  . ARG A 1 420 ? 78.438  80.517  87.121  1.00 23.11 ? 399  ARG A CB  1 
ATOM   2980  C CG  . ARG A 1 420 ? 78.339  79.038  87.440  1.00 23.11 ? 399  ARG A CG  1 
ATOM   2981  C CD  . ARG A 1 420 ? 78.699  78.197  86.227  1.00 23.11 ? 399  ARG A CD  1 
ATOM   2982  N NE  . ARG A 1 420 ? 79.996  78.570  85.670  1.00 23.11 ? 399  ARG A NE  1 
ATOM   2983  C CZ  . ARG A 1 420 ? 80.407  78.242  84.450  1.00 23.11 ? 399  ARG A CZ  1 
ATOM   2984  N NH1 . ARG A 1 420 ? 79.621  77.534  83.651  1.00 23.11 ? 399  ARG A NH1 1 
ATOM   2985  N NH2 . ARG A 1 420 ? 81.603  78.621  84.026  1.00 23.11 ? 399  ARG A NH2 1 
ATOM   2986  N N   . ILE A 1 421 ? 77.784  83.585  87.234  1.00 19.30 ? 400  ILE A N   1 
ATOM   2987  C CA  . ILE A 1 421 ? 78.133  84.926  86.788  1.00 19.30 ? 400  ILE A CA  1 
ATOM   2988  C C   . ILE A 1 421 ? 78.301  85.902  87.943  1.00 19.30 ? 400  ILE A C   1 
ATOM   2989  O O   . ILE A 1 421 ? 78.882  86.972  87.757  1.00 19.30 ? 400  ILE A O   1 
ATOM   2990  C CB  . ILE A 1 421 ? 77.083  85.450  85.787  1.00 19.30 ? 400  ILE A CB  1 
ATOM   2991  C CG1 . ILE A 1 421 ? 75.716  85.572  86.454  1.00 19.30 ? 400  ILE A CG1 1 
ATOM   2992  C CG2 . ILE A 1 421 ? 77.004  84.541  84.582  1.00 19.30 ? 400  ILE A CG2 1 
ATOM   2993  C CD1 . ILE A 1 421 ? 74.665  86.148  85.553  1.00 19.30 ? 400  ILE A CD1 1 
ATOM   2994  N N   . PHE A 1 422 ? 77.802  85.562  89.128  1.00 16.80 ? 401  PHE A N   1 
ATOM   2995  C CA  . PHE A 1 422 ? 78.110  86.311  90.337  1.00 16.80 ? 401  PHE A CA  1 
ATOM   2996  C C   . PHE A 1 422 ? 79.407  85.864  90.989  1.00 16.80 ? 401  PHE A C   1 
ATOM   2997  O O   . PHE A 1 422 ? 79.989  86.626  91.768  1.00 16.80 ? 401  PHE A O   1 
ATOM   2998  C CB  . PHE A 1 422 ? 76.983  86.159  91.355  1.00 16.80 ? 401  PHE A CB  1 
ATOM   2999  C CG  . PHE A 1 422 ? 75.902  87.181  91.226  1.00 16.80 ? 401  PHE A CG  1 
ATOM   3000  C CD1 . PHE A 1 422 ? 74.898  87.029  90.288  1.00 16.80 ? 401  PHE A CD1 1 
ATOM   3001  C CD2 . PHE A 1 422 ? 75.873  88.283  92.062  1.00 16.80 ? 401  PHE A CD2 1 
ATOM   3002  C CE1 . PHE A 1 422 ? 73.891  87.959  90.184  1.00 16.80 ? 401  PHE A CE1 1 
ATOM   3003  C CE2 . PHE A 1 422 ? 74.871  89.221  91.960  1.00 16.80 ? 401  PHE A CE2 1 
ATOM   3004  C CZ  . PHE A 1 422 ? 73.879  89.060  91.021  1.00 16.80 ? 401  PHE A CZ  1 
ATOM   3005  N N   . GLN A 1 423 ? 79.861  84.646  90.701  1.00 21.19 ? 402  GLN A N   1 
ATOM   3006  C CA  . GLN A 1 423 ? 81.056  84.086  91.311  1.00 21.19 ? 402  GLN A CA  1 
ATOM   3007  C C   . GLN A 1 423 ? 82.214  83.941  90.336  1.00 21.19 ? 402  GLN A C   1 
ATOM   3008  O O   . GLN A 1 423 ? 83.255  83.393  90.710  1.00 21.19 ? 402  GLN A O   1 
ATOM   3009  C CB  . GLN A 1 423 ? 80.739  82.722  91.935  1.00 21.19 ? 402  GLN A CB  1 
ATOM   3010  C CG  . GLN A 1 423 ? 79.695  82.770  93.037  1.00 21.19 ? 402  GLN A CG  1 
ATOM   3011  C CD  . GLN A 1 423 ? 80.230  83.356  94.329  1.00 21.19 ? 402  GLN A CD  1 
ATOM   3012  O OE1 . GLN A 1 423 ? 80.723  82.634  95.195  1.00 21.19 ? 402  GLN A OE1 1 
ATOM   3013  N NE2 . GLN A 1 423 ? 80.133  84.672  94.467  1.00 21.19 ? 402  GLN A NE2 1 
ATOM   3014  N N   . GLU A 1 424 ? 82.068  84.410  89.102  1.00 21.87 ? 403  GLU A N   1 
ATOM   3015  C CA  . GLU A 1 424 ? 83.126  84.293  88.113  1.00 21.87 ? 403  GLU A CA  1 
ATOM   3016  C C   . GLU A 1 424 ? 83.285  85.624  87.396  1.00 21.87 ? 403  GLU A C   1 
ATOM   3017  O O   . GLU A 1 424 ? 82.326  86.385  87.249  1.00 21.87 ? 403  GLU A O   1 
ATOM   3018  C CB  . GLU A 1 424 ? 82.841  83.162  87.119  1.00 21.87 ? 403  GLU A CB  1 
ATOM   3019  C CG  . GLU A 1 424 ? 82.762  81.788  87.776  1.00 21.87 ? 403  GLU A CG  1 
ATOM   3020  C CD  . GLU A 1 424 ? 82.601  80.661  86.779  1.00 21.87 ? 403  GLU A CD  1 
ATOM   3021  O OE1 . GLU A 1 424 ? 83.628  80.117  86.327  1.00 21.87 ? 403  GLU A OE1 1 
ATOM   3022  O OE2 . GLU A 1 424 ? 81.450  80.312  86.453  1.00 21.87 ? 403  GLU A OE2 1 
ATOM   3023  N N   . GLU A 1 425 ? 84.508  85.896  86.954  1.00 19.08 ? 404  GLU A N   1 
ATOM   3024  C CA  . GLU A 1 425 ? 84.887  87.207  86.447  1.00 19.08 ? 404  GLU A CA  1 
ATOM   3025  C C   . GLU A 1 425 ? 84.825  87.233  84.927  1.00 19.08 ? 404  GLU A C   1 
ATOM   3026  O O   . GLU A 1 425 ? 85.284  86.302  84.260  1.00 19.08 ? 404  GLU A O   1 
ATOM   3027  C CB  . GLU A 1 425 ? 86.289  87.575  86.923  1.00 19.08 ? 404  GLU A CB  1 
ATOM   3028  C CG  . GLU A 1 425 ? 86.527  89.057  87.031  1.00 19.08 ? 404  GLU A CG  1 
ATOM   3029  C CD  . GLU A 1 425 ? 87.721  89.372  87.892  1.00 19.08 ? 404  GLU A CD  1 
ATOM   3030  O OE1 . GLU A 1 425 ? 88.305  90.459  87.727  1.00 19.08 ? 404  GLU A OE1 1 
ATOM   3031  O OE2 . GLU A 1 425 ? 88.073  88.527  88.739  1.00 19.08 ? 404  GLU A OE2 1 
ATOM   3032  N N   . ILE A 1 426 ? 84.264  88.310  84.386  1.00 18.06 ? 405  ILE A N   1 
ATOM   3033  C CA  . ILE A 1 426 ? 83.881  88.371  82.986  1.00 18.06 ? 405  ILE A CA  1 
ATOM   3034  C C   . ILE A 1 426 ? 84.800  89.277  82.174  1.00 18.06 ? 405  ILE A C   1 
ATOM   3035  O O   . ILE A 1 426 ? 85.213  88.907  81.073  1.00 18.06 ? 405  ILE A O   1 
ATOM   3036  C CB  . ILE A 1 426 ? 82.409  88.815  82.853  1.00 18.06 ? 405  ILE A CB  1 
ATOM   3037  C CG1 . ILE A 1 426 ? 81.522  87.975  83.770  1.00 18.06 ? 405  ILE A CG1 1 
ATOM   3038  C CG2 . ILE A 1 426 ? 81.941  88.674  81.428  1.00 18.06 ? 405  ILE A CG2 1 
ATOM   3039  C CD1 . ILE A 1 426 ? 80.053  88.283  83.642  1.00 18.06 ? 405  ILE A CD1 1 
ATOM   3040  N N   . PHE A 1 427 ? 85.135  90.460  82.694  1.00 16.67 ? 406  PHE A N   1 
ATOM   3041  C CA  . PHE A 1 427 ? 85.808  91.510  81.921  1.00 16.67 ? 406  PHE A CA  1 
ATOM   3042  C C   . PHE A 1 427 ? 85.034  91.864  80.652  1.00 16.67 ? 406  PHE A C   1 
ATOM   3043  O O   . PHE A 1 427 ? 85.549  91.805  79.536  1.00 16.67 ? 406  PHE A O   1 
ATOM   3044  C CB  . PHE A 1 427 ? 87.260  91.149  81.588  1.00 16.67 ? 406  PHE A CB  1 
ATOM   3045  C CG  . PHE A 1 427 ? 88.169  91.134  82.772  1.00 16.67 ? 406  PHE A CG  1 
ATOM   3046  C CD1 . PHE A 1 427 ? 87.778  91.714  83.966  1.00 16.67 ? 406  PHE A CD1 1 
ATOM   3047  C CD2 . PHE A 1 427 ? 89.434  90.585  82.680  1.00 16.67 ? 406  PHE A CD2 1 
ATOM   3048  C CE1 . PHE A 1 427 ? 88.622  91.724  85.052  1.00 16.67 ? 406  PHE A CE1 1 
ATOM   3049  C CE2 . PHE A 1 427 ? 90.285  90.588  83.766  1.00 16.67 ? 406  PHE A CE2 1 
ATOM   3050  C CZ  . PHE A 1 427 ? 89.878  91.158  84.955  1.00 16.67 ? 406  PHE A CZ  1 
ATOM   3051  N N   . GLY A 1 428 ? 83.787  92.269  80.852  1.00 10.58 ? 407  GLY A N   1 
ATOM   3052  C CA  . GLY A 1 428 ? 82.970  92.771  79.779  1.00 10.58 ? 407  GLY A CA  1 
ATOM   3053  C C   . GLY A 1 428 ? 81.932  93.727  80.314  1.00 10.58 ? 407  GLY A C   1 
ATOM   3054  O O   . GLY A 1 428 ? 81.712  93.817  81.524  1.00 10.58 ? 407  GLY A O   1 
ATOM   3055  N N   . PRO A 1 429 ? 81.269  94.459  79.431  1.00 8.30  ? 408  PRO A N   1 
ATOM   3056  C CA  . PRO A 1 429 ? 80.252  95.409  79.895  1.00 8.30  ? 408  PRO A CA  1 
ATOM   3057  C C   . PRO A 1 429 ? 79.024  94.693  80.418  1.00 8.30  ? 408  PRO A C   1 
ATOM   3058  O O   . PRO A 1 429 ? 77.907  94.929  79.953  1.00 8.30  ? 408  PRO A O   1 
ATOM   3059  C CB  . PRO A 1 429 ? 79.940  96.225  78.638  1.00 8.30  ? 408  PRO A CB  1 
ATOM   3060  C CG  . PRO A 1 429 ? 80.255  95.304  77.521  1.00 8.30  ? 408  PRO A CG  1 
ATOM   3061  C CD  . PRO A 1 429 ? 81.414  94.474  77.968  1.00 8.30  ? 408  PRO A CD  1 
ATOM   3062  N N   . VAL A 1 430 ? 79.226  93.812  81.393  1.00 7.32  ? 409  VAL A N   1 
ATOM   3063  C CA  . VAL A 1 430 ? 78.180  92.950  81.923  1.00 7.32  ? 409  VAL A CA  1 
ATOM   3064  C C   . VAL A 1 430 ? 78.155  93.119  83.429  1.00 7.32  ? 409  VAL A C   1 
ATOM   3065  O O   . VAL A 1 430 ? 79.173  92.908  84.095  1.00 7.32  ? 409  VAL A O   1 
ATOM   3066  C CB  . VAL A 1 430 ? 78.411  91.478  81.558  1.00 7.32  ? 409  VAL A CB  1 
ATOM   3067  C CG1 . VAL A 1 430 ? 77.361  90.616  82.204  1.00 7.32  ? 409  VAL A CG1 1 
ATOM   3068  C CG2 . VAL A 1 430 ? 78.408  91.302  80.059  1.00 7.32  ? 409  VAL A CG2 1 
ATOM   3069  N N   . VAL A 1 431 ? 76.999  93.481  83.967  1.00 7.08  ? 410  VAL A N   1 
ATOM   3070  C CA  . VAL A 1 431 ? 76.833  93.688  85.396  1.00 7.08  ? 410  VAL A CA  1 
ATOM   3071  C C   . VAL A 1 431 ? 75.709  92.786  85.885  1.00 7.08  ? 410  VAL A C   1 
ATOM   3072  O O   . VAL A 1 431 ? 74.665  92.673  85.235  1.00 7.08  ? 410  VAL A O   1 
ATOM   3073  C CB  . VAL A 1 431 ? 76.562  95.167  85.726  1.00 7.08  ? 410  VAL A CB  1 
ATOM   3074  C CG1 . VAL A 1 431 ? 75.255  95.636  85.124  1.00 7.08  ? 410  VAL A CG1 1 
ATOM   3075  C CG2 . VAL A 1 431 ? 76.580  95.384  87.218  1.00 7.08  ? 410  VAL A CG2 1 
ATOM   3076  N N   . SER A 1 432 ? 75.942  92.117  87.008  1.00 7.59  ? 411  SER A N   1 
ATOM   3077  C CA  . SER A 1 432 ? 74.971  91.222  87.614  1.00 7.59  ? 411  SER A CA  1 
ATOM   3078  C C   . SER A 1 432 ? 74.440  91.861  88.886  1.00 7.59  ? 411  SER A C   1 
ATOM   3079  O O   . SER A 1 432 ? 75.218  92.323  89.723  1.00 7.59  ? 411  SER A O   1 
ATOM   3080  C CB  . SER A 1 432 ? 75.600  89.866  87.918  1.00 7.59  ? 411  SER A CB  1 
ATOM   3081  O OG  . SER A 1 432 ? 76.816  90.030  88.619  1.00 7.59  ? 411  SER A OG  1 
ATOM   3082  N N   . VAL A 1 433 ? 73.122  91.878  89.032  1.00 8.21  ? 412  VAL A N   1 
ATOM   3083  C CA  . VAL A 1 433 ? 72.454  92.643  90.074  1.00 8.21  ? 412  VAL A CA  1 
ATOM   3084  C C   . VAL A 1 433 ? 71.691  91.703  90.991  1.00 8.21  ? 412  VAL A C   1 
ATOM   3085  O O   . VAL A 1 433 ? 70.947  90.832  90.526  1.00 8.21  ? 412  VAL A O   1 
ATOM   3086  C CB  . VAL A 1 433 ? 71.506  93.687  89.462  1.00 8.21  ? 412  VAL A CB  1 
ATOM   3087  C CG1 . VAL A 1 433 ? 70.913  94.551  90.551  1.00 8.21  ? 412  VAL A CG1 1 
ATOM   3088  C CG2 . VAL A 1 433 ? 72.244  94.519  88.439  1.00 8.21  ? 412  VAL A CG2 1 
ATOM   3089  N N   . THR A 1 434 ? 71.870  91.883  92.295  1.00 11.00 ? 413  THR A N   1 
ATOM   3090  C CA  . THR A 1 434 ? 71.069  91.178  93.283  1.00 11.00 ? 413  THR A CA  1 
ATOM   3091  C C   . THR A 1 434 ? 70.691  92.166  94.375  1.00 11.00 ? 413  THR A C   1 
ATOM   3092  O O   . THR A 1 434 ? 71.061  93.340  94.332  1.00 11.00 ? 413  THR A O   1 
ATOM   3093  C CB  . THR A 1 434 ? 71.809  89.969  93.856  1.00 11.00 ? 413  THR A CB  1 
ATOM   3094  O OG1 . THR A 1 434 ? 70.913  89.201  94.669  1.00 11.00 ? 413  THR A OG1 1 
ATOM   3095  C CG2 . THR A 1 434 ? 72.973  90.418  94.701  1.00 11.00 ? 413  THR A CG2 1 
ATOM   3096  N N   . THR A 1 435 ? 69.942  91.686  95.359  1.00 12.05 ? 414  THR A N   1 
ATOM   3097  C CA  . THR A 1 435 ? 69.446  92.530  96.431  1.00 12.05 ? 414  THR A CA  1 
ATOM   3098  C C   . THR A 1 435 ? 69.851  91.966  97.784  1.00 12.05 ? 414  THR A C   1 
ATOM   3099  O O   . THR A 1 435 ? 70.043  90.759  97.941  1.00 12.05 ? 414  THR A O   1 
ATOM   3100  C CB  . THR A 1 435 ? 67.920  92.672  96.373  1.00 12.05 ? 414  THR A CB  1 
ATOM   3101  O OG1 . THR A 1 435 ? 67.307  91.436  96.762  1.00 12.05 ? 414  THR A OG1 1 
ATOM   3102  C CG2 . THR A 1 435 ? 67.471  93.036  94.971  1.00 12.05 ? 414  THR A CG2 1 
ATOM   3103  N N   . PHE A 1 436 ? 69.986  92.857  98.758  1.00 12.63 ? 415  PHE A N   1 
ATOM   3104  C CA  . PHE A 1 436 ? 70.211  92.469  100.138 1.00 12.63 ? 415  PHE A CA  1 
ATOM   3105  C C   . PHE A 1 436 ? 69.173  93.153  101.014 1.00 12.63 ? 415  PHE A C   1 
ATOM   3106  O O   . PHE A 1 436 ? 68.570  94.156  100.628 1.00 12.63 ? 415  PHE A O   1 
ATOM   3107  C CB  . PHE A 1 436 ? 71.634  92.812  100.606 1.00 12.63 ? 415  PHE A CB  1 
ATOM   3108  C CG  . PHE A 1 436 ? 71.957  94.278  100.578 1.00 12.63 ? 415  PHE A CG  1 
ATOM   3109  C CD1 . PHE A 1 436 ? 71.610  95.100  101.634 1.00 12.63 ? 415  PHE A CD1 1 
ATOM   3110  C CD2 . PHE A 1 436 ? 72.630  94.828  99.507  1.00 12.63 ? 415  PHE A CD2 1 
ATOM   3111  C CE1 . PHE A 1 436 ? 71.909  96.437  101.612 1.00 12.63 ? 415  PHE A CE1 1 
ATOM   3112  C CE2 . PHE A 1 436 ? 72.932  96.168  99.482  1.00 12.63 ? 415  PHE A CE2 1 
ATOM   3113  C CZ  . PHE A 1 436 ? 72.571  96.973  100.536 1.00 12.63 ? 415  PHE A CZ  1 
ATOM   3114  N N   . LYS A 1 437 ? 68.961  92.592  102.203 1.00 17.80 ? 416  LYS A N   1 
ATOM   3115  C CA  . LYS A 1 437 ? 67.958  93.120  103.119 1.00 17.80 ? 416  LYS A CA  1 
ATOM   3116  C C   . LYS A 1 437 ? 68.525  94.193  104.043 1.00 17.80 ? 416  LYS A C   1 
ATOM   3117  O O   . LYS A 1 437 ? 67.984  95.300  104.118 1.00 17.80 ? 416  LYS A O   1 
ATOM   3118  C CB  . LYS A 1 437 ? 67.352  91.983  103.946 1.00 17.80 ? 416  LYS A CB  1 
ATOM   3119  C CG  . LYS A 1 437 ? 65.971  92.288  104.489 1.00 17.80 ? 416  LYS A CG  1 
ATOM   3120  C CD  . LYS A 1 437 ? 65.003  92.619  103.369 1.00 17.80 ? 416  LYS A CD  1 
ATOM   3121  C CE  . LYS A 1 437 ? 64.393  91.360  102.777 1.00 17.80 ? 416  LYS A CE  1 
ATOM   3122  N NZ  . LYS A 1 437 ? 63.385  91.673  101.727 1.00 17.80 ? 416  LYS A NZ  1 
ATOM   3123  N N   . ASP A 1 438 ? 69.610  93.880  104.750 1.00 20.48 ? 417  ASP A N   1 
ATOM   3124  C CA  . ASP A 1 438 ? 70.202  94.812  105.700 1.00 20.48 ? 417  ASP A CA  1 
ATOM   3125  C C   . ASP A 1 438 ? 71.717  94.836  105.561 1.00 20.48 ? 417  ASP A C   1 
ATOM   3126  O O   . ASP A 1 438 ? 72.267  94.276  104.608 1.00 20.48 ? 417  ASP A O   1 
ATOM   3127  C CB  . ASP A 1 438 ? 69.809  94.442  107.130 1.00 20.48 ? 417  ASP A CB  1 
ATOM   3128  C CG  . ASP A 1 438 ? 70.383  93.111  107.564 1.00 20.48 ? 417  ASP A CG  1 
ATOM   3129  O OD1 . ASP A 1 438 ? 70.247  92.130  106.804 1.00 20.48 ? 417  ASP A OD1 1 
ATOM   3130  O OD2 . ASP A 1 438 ? 70.972  93.044  108.663 1.00 20.48 ? 417  ASP A OD2 1 
ATOM   3131  N N   . GLN A 1 439 ? 72.400  95.481  106.510 1.00 18.17 ? 418  GLN A N   1 
ATOM   3132  C CA  . GLN A 1 439 ? 73.849  95.620  106.412 1.00 18.17 ? 418  GLN A CA  1 
ATOM   3133  C C   . GLN A 1 439 ? 74.557  94.276  106.515 1.00 18.17 ? 418  GLN A C   1 
ATOM   3134  O O   . GLN A 1 439 ? 75.552  94.042  105.819 1.00 18.17 ? 418  GLN A O   1 
ATOM   3135  C CB  . GLN A 1 439 ? 74.363  96.569  107.488 1.00 18.17 ? 418  GLN A CB  1 
ATOM   3136  C CG  . GLN A 1 439 ? 73.936  98.008  107.302 1.00 18.17 ? 418  GLN A CG  1 
ATOM   3137  C CD  . GLN A 1 439 ? 74.920  98.967  107.924 1.00 18.17 ? 418  GLN A CD  1 
ATOM   3138  O OE1 . GLN A 1 439 ? 76.131  98.759  107.852 1.00 18.17 ? 418  GLN A OE1 1 
ATOM   3139  N NE2 . GLN A 1 439 ? 74.410  100.023 108.541 1.00 18.17 ? 418  GLN A NE2 1 
ATOM   3140  N N   . ALA A 1 440 ? 74.082  93.390  107.393 1.00 18.80 ? 419  ALA A N   1 
ATOM   3141  C CA  . ALA A 1 440 ? 74.752  92.106  107.571 1.00 18.80 ? 419  ALA A CA  1 
ATOM   3142  C C   . ALA A 1 440 ? 74.718  91.280  106.291 1.00 18.80 ? 419  ALA A C   1 
ATOM   3143  O O   . ALA A 1 440 ? 75.729  90.686  105.896 1.00 18.80 ? 419  ALA A O   1 
ATOM   3144  C CB  . ALA A 1 440 ? 74.110  91.340  108.725 1.00 18.80 ? 419  ALA A CB  1 
ATOM   3145  N N   . GLU A 1 441 ? 73.562  91.232  105.627 1.00 18.59 ? 420  GLU A N   1 
ATOM   3146  C CA  . GLU A 1 441 ? 73.487  90.536  104.350 1.00 18.59 ? 420  GLU A CA  1 
ATOM   3147  C C   . GLU A 1 441 ? 74.367  91.212  103.310 1.00 18.59 ? 420  GLU A C   1 
ATOM   3148  O O   . GLU A 1 441 ? 74.938  90.539  102.445 1.00 18.59 ? 420  GLU A O   1 
ATOM   3149  C CB  . GLU A 1 441 ? 72.038  90.472  103.870 1.00 18.59 ? 420  GLU A CB  1 
ATOM   3150  C CG  . GLU A 1 441 ? 71.735  89.267  102.994 1.00 18.59 ? 420  GLU A CG  1 
ATOM   3151  C CD  . GLU A 1 441 ? 70.317  89.274  102.456 1.00 18.59 ? 420  GLU A CD  1 
ATOM   3152  O OE1 . GLU A 1 441 ? 69.652  90.326  102.541 1.00 18.59 ? 420  GLU A OE1 1 
ATOM   3153  O OE2 . GLU A 1 441 ? 69.864  88.225  101.957 1.00 18.59 ? 420  GLU A OE2 1 
ATOM   3154  N N   . ALA A 1 442 ? 74.495  92.537  103.387 1.00 16.16 ? 421  ALA A N   1 
ATOM   3155  C CA  . ALA A 1 442 ? 75.386  93.252  102.483 1.00 16.16 ? 421  ALA A CA  1 
ATOM   3156  C C   . ALA A 1 442 ? 76.826  92.792  102.659 1.00 16.16 ? 421  ALA A C   1 
ATOM   3157  O O   . ALA A 1 442 ? 77.518  92.502  101.678 1.00 16.16 ? 421  ALA A O   1 
ATOM   3158  C CB  . ALA A 1 442 ? 75.265  94.756  102.712 1.00 16.16 ? 421  ALA A CB  1 
ATOM   3159  N N   . LEU A 1 443 ? 77.293  92.699  103.910 1.00 16.93 ? 422  LEU A N   1 
ATOM   3160  C CA  . LEU A 1 443 ? 78.639  92.185  104.148 1.00 16.93 ? 422  LEU A CA  1 
ATOM   3161  C C   . LEU A 1 443 ? 78.779  90.747  103.676 1.00 16.93 ? 422  LEU A C   1 
ATOM   3162  O O   . LEU A 1 443 ? 79.793  90.385  103.069 1.00 16.93 ? 422  LEU A O   1 
ATOM   3163  C CB  . LEU A 1 443 ? 79.023  92.266  105.623 1.00 16.93 ? 422  LEU A CB  1 
ATOM   3164  C CG  . LEU A 1 443 ? 79.572  93.559  106.220 1.00 16.93 ? 422  LEU A CG  1 
ATOM   3165  C CD1 . LEU A 1 443 ? 80.898  93.896  105.553 1.00 16.93 ? 422  LEU A CD1 1 
ATOM   3166  C CD2 . LEU A 1 443 ? 78.601  94.713  106.169 1.00 16.93 ? 422  LEU A CD2 1 
ATOM   3167  N N   . GLU A 1 444 ? 77.787  89.905  103.965 1.00 17.69 ? 423  GLU A N   1 
ATOM   3168  C CA  . GLU A 1 444 ? 77.898  88.499  103.593 1.00 17.69 ? 423  GLU A CA  1 
ATOM   3169  C C   . GLU A 1 444 ? 78.016  88.338  102.082 1.00 17.69 ? 423  GLU A C   1 
ATOM   3170  O O   . GLU A 1 444 ? 78.867  87.589  101.591 1.00 17.69 ? 423  GLU A O   1 
ATOM   3171  C CB  . GLU A 1 444 ? 76.702  87.711  104.124 1.00 17.69 ? 423  GLU A CB  1 
ATOM   3172  C CG  . GLU A 1 444 ? 76.594  86.319  103.532 1.00 17.69 ? 423  GLU A CG  1 
ATOM   3173  C CD  . GLU A 1 444 ? 75.366  85.574  104.002 1.00 17.69 ? 423  GLU A CD  1 
ATOM   3174  O OE1 . GLU A 1 444 ? 74.594  86.140  104.804 1.00 17.69 ? 423  GLU A OE1 1 
ATOM   3175  O OE2 . GLU A 1 444 ? 75.178  84.417  103.571 1.00 17.69 ? 423  GLU A OE2 1 
ATOM   3176  N N   . ILE A 1 445 ? 77.176  89.043  101.325 1.00 14.06 ? 424  ILE A N   1 
ATOM   3177  C CA  . ILE A 1 445 ? 77.219  88.913  99.873  1.00 14.06 ? 424  ILE A CA  1 
ATOM   3178  C C   . ILE A 1 445 ? 78.481  89.555  99.310  1.00 14.06 ? 424  ILE A C   1 
ATOM   3179  O O   . ILE A 1 445 ? 79.108  89.012  98.394  1.00 14.06 ? 424  ILE A O   1 
ATOM   3180  C CB  . ILE A 1 445 ? 75.948  89.505  99.243  1.00 14.06 ? 424  ILE A CB  1 
ATOM   3181  C CG1 . ILE A 1 445 ? 74.713  88.758  99.747  1.00 14.06 ? 424  ILE A CG1 1 
ATOM   3182  C CG2 . ILE A 1 445 ? 76.025  89.444  97.730  1.00 14.06 ? 424  ILE A CG2 1 
ATOM   3183  C CD1 . ILE A 1 445 ? 73.452  89.576  99.711  1.00 14.06 ? 424  ILE A CD1 1 
ATOM   3184  N N   . ALA A 1 446 ? 78.877  90.716  99.843  1.00 13.73 ? 425  ALA A N   1 
ATOM   3185  C CA  . ALA A 1 446 ? 80.068  91.393  99.343  1.00 13.73 ? 425  ALA A CA  1 
ATOM   3186  C C   . ALA A 1 446 ? 81.317  90.552  99.557  1.00 13.73 ? 425  ALA A C   1 
ATOM   3187  O O   . ALA A 1 446 ? 82.160  90.437  98.659  1.00 13.73 ? 425  ALA A O   1 
ATOM   3188  C CB  . ALA A 1 446 ? 80.220  92.749  100.025 1.00 13.73 ? 425  ALA A CB  1 
ATOM   3189  N N   . ASN A 1 447 ? 81.454  89.954  100.738 1.00 13.83 ? 426  ASN A N   1 
ATOM   3190  C CA  . ASN A 1 447 ? 82.651  89.196  101.062 1.00 13.83 ? 426  ASN A CA  1 
ATOM   3191  C C   . ASN A 1 447 ? 82.644  87.793  100.476 1.00 13.83 ? 426  ASN A C   1 
ATOM   3192  O O   . ASN A 1 447 ? 83.716  87.198  100.324 1.00 13.83 ? 426  ASN A O   1 
ATOM   3193  C CB  . ASN A 1 447 ? 82.823  89.126  102.577 1.00 13.83 ? 426  ASN A CB  1 
ATOM   3194  C CG  . ASN A 1 447 ? 83.445  90.377  103.142 1.00 13.83 ? 426  ASN A CG  1 
ATOM   3195  O OD1 . ASN A 1 447 ? 84.495  90.817  102.687 1.00 13.83 ? 426  ASN A OD1 1 
ATOM   3196  N ND2 . ASN A 1 447 ? 82.796  90.965  104.133 1.00 13.83 ? 426  ASN A ND2 1 
ATOM   3197  N N   . ASP A 1 448 ? 81.476  87.253  100.131 1.00 18.42 ? 427  ASP A N   1 
ATOM   3198  C CA  . ASP A 1 448 ? 81.385  85.890  99.608  1.00 18.42 ? 427  ASP A CA  1 
ATOM   3199  C C   . ASP A 1 448 ? 81.882  85.887  98.164  1.00 18.42 ? 427  ASP A C   1 
ATOM   3200  O O   . ASP A 1 448 ? 81.119  85.995  97.202  1.00 18.42 ? 427  ASP A O   1 
ATOM   3201  C CB  . ASP A 1 448 ? 79.959  85.366  99.718  1.00 18.42 ? 427  ASP A CB  1 
ATOM   3202  C CG  . ASP A 1 448 ? 79.812  83.951  99.201  1.00 18.42 ? 427  ASP A CG  1 
ATOM   3203  O OD1 . ASP A 1 448 ? 79.659  83.778  97.975  1.00 18.42 ? 427  ASP A OD1 1 
ATOM   3204  O OD2 . ASP A 1 448 ? 79.838  83.010  100.023 1.00 18.42 ? 427  ASP A OD2 1 
ATOM   3205  N N   . THR A 1 449 ? 83.199  85.769  98.024  1.00 19.22 ? 428  THR A N   1 
ATOM   3206  C CA  . THR A 1 449 ? 83.871  85.703  96.732  1.00 19.22 ? 428  THR A CA  1 
ATOM   3207  C C   . THR A 1 449 ? 85.304  85.256  96.980  1.00 19.22 ? 428  THR A C   1 
ATOM   3208  O O   . THR A 1 449 ? 85.748  85.139  98.124  1.00 19.22 ? 428  THR A O   1 
ATOM   3209  C CB  . THR A 1 449 ? 83.837  87.045  95.999  1.00 19.22 ? 428  THR A CB  1 
ATOM   3210  O OG1 . THR A 1 449 ? 84.614  86.958  94.799  1.00 19.22 ? 428  THR A OG1 1 
ATOM   3211  C CG2 . THR A 1 449 ? 84.393  88.144  96.875  1.00 19.22 ? 428  THR A CG2 1 
ATOM   3212  N N   . LEU A 1 450 ? 86.025  85.006  95.892  1.00 23.73 ? 429  LEU A N   1 
ATOM   3213  C CA  . LEU A 1 450 ? 87.420  84.595  95.962  1.00 23.73 ? 429  LEU A CA  1 
ATOM   3214  C C   . LEU A 1 450 ? 88.376  85.736  95.665  1.00 23.73 ? 429  LEU A C   1 
ATOM   3215  O O   . LEU A 1 450 ? 89.570  85.495  95.467  1.00 23.73 ? 429  LEU A O   1 
ATOM   3216  C CB  . LEU A 1 450 ? 87.689  83.441  94.996  1.00 23.73 ? 429  LEU A CB  1 
ATOM   3217  C CG  . LEU A 1 450 ? 86.658  82.319  94.889  1.00 23.73 ? 429  LEU A CG  1 
ATOM   3218  C CD1 . LEU A 1 450 ? 87.172  81.251  93.942  1.00 23.73 ? 429  LEU A CD1 1 
ATOM   3219  C CD2 . LEU A 1 450 ? 86.353  81.728  96.256  1.00 23.73 ? 429  LEU A CD2 1 
ATOM   3220  N N   . TYR A 1 451 ? 87.881  86.970  95.628  1.00 20.11 ? 430  TYR A N   1 
ATOM   3221  C CA  . TYR A 1 451 ? 88.685  88.118  95.250  1.00 20.11 ? 430  TYR A CA  1 
ATOM   3222  C C   . TYR A 1 451 ? 88.435  89.253  96.228  1.00 20.11 ? 430  TYR A C   1 
ATOM   3223  O O   . TYR A 1 451 ? 87.373  89.339  96.846  1.00 20.11 ? 430  TYR A O   1 
ATOM   3224  C CB  . TYR A 1 451 ? 88.359  88.583  93.833  1.00 20.11 ? 430  TYR A CB  1 
ATOM   3225  C CG  . TYR A 1 451 ? 88.403  87.487  92.800  1.00 20.11 ? 430  TYR A CG  1 
ATOM   3226  C CD1 . TYR A 1 451 ? 89.557  86.752  92.591  1.00 20.11 ? 430  TYR A CD1 1 
ATOM   3227  C CD2 . TYR A 1 451 ? 87.287  87.184  92.035  1.00 20.11 ? 430  TYR A CD2 1 
ATOM   3228  C CE1 . TYR A 1 451 ? 89.601  85.748  91.649  1.00 20.11 ? 430  TYR A CE1 1 
ATOM   3229  C CE2 . TYR A 1 451 ? 87.321  86.182  91.091  1.00 20.11 ? 430  TYR A CE2 1 
ATOM   3230  C CZ  . TYR A 1 451 ? 88.482  85.467  90.902  1.00 20.11 ? 430  TYR A CZ  1 
ATOM   3231  O OH  . TYR A 1 451 ? 88.528  84.464  89.961  1.00 20.11 ? 430  TYR A OH  1 
ATOM   3232  N N   . GLY A 1 452 ? 89.427  90.121  96.364  1.00 12.84 ? 431  GLY A N   1 
ATOM   3233  C CA  . GLY A 1 452 ? 89.291  91.280  97.215  1.00 12.84 ? 431  GLY A CA  1 
ATOM   3234  C C   . GLY A 1 452 ? 89.926  92.521  96.630  1.00 12.84 ? 431  GLY A C   1 
ATOM   3235  O O   . GLY A 1 452 ? 90.450  93.355  97.367  1.00 12.84 ? 431  GLY A O   1 
ATOM   3236  N N   . LEU A 1 453 ? 89.923  92.651  95.306  1.00 11.77 ? 432  LEU A N   1 
ATOM   3237  C CA  . LEU A 1 453 ? 90.699  93.722  94.692  1.00 11.77 ? 432  LEU A CA  1 
ATOM   3238  C C   . LEU A 1 453 ? 90.067  95.089  94.939  1.00 11.77 ? 432  LEU A C   1 
ATOM   3239  O O   . LEU A 1 453 ? 90.760  96.041  95.311  1.00 11.77 ? 432  LEU A O   1 
ATOM   3240  C CB  . LEU A 1 453 ? 90.878  93.447  93.203  1.00 11.77 ? 432  LEU A CB  1 
ATOM   3241  C CG  . LEU A 1 453 ? 91.738  94.477  92.487  1.00 11.77 ? 432  LEU A CG  1 
ATOM   3242  C CD1 . LEU A 1 453 ? 93.125  94.465  93.066  1.00 11.77 ? 432  LEU A CD1 1 
ATOM   3243  C CD2 . LEU A 1 453 ? 91.809  94.134  91.019  1.00 11.77 ? 432  LEU A CD2 1 
ATOM   3244  N N   . GLY A 1 454 ? 88.755  95.210  94.749  1.00 6.90  ? 433  GLY A N   1 
ATOM   3245  C CA  . GLY A 1 454 ? 88.097  96.489  94.916  1.00 6.90  ? 433  GLY A CA  1 
ATOM   3246  C C   . GLY A 1 454 ? 86.653  96.319  95.327  1.00 6.90  ? 433  GLY A C   1 
ATOM   3247  O O   . GLY A 1 454 ? 86.101  95.219  95.293  1.00 6.90  ? 433  GLY A O   1 
ATOM   3248  N N   . ALA A 1 455 ? 86.047  97.432  95.732  1.00 4.84  ? 434  ALA A N   1 
ATOM   3249  C CA  . ALA A 1 455 ? 84.646  97.459  96.127  1.00 4.84  ? 434  ALA A CA  1 
ATOM   3250  C C   . ALA A 1 455 ? 84.177  98.905  96.136  1.00 4.84  ? 434  ALA A C   1 
ATOM   3251  O O   . ALA A 1 455 ? 84.981  99.835  96.139  1.00 4.84  ? 434  ALA A O   1 
ATOM   3252  C CB  . ALA A 1 455 ? 84.436  96.809  97.493  1.00 4.84  ? 434  ALA A CB  1 
ATOM   3253  N N   . GLY A 1 456 ? 82.859  99.084  96.140  1.00 4.00  ? 435  GLY A N   1 
ATOM   3254  C CA  . GLY A 1 456 ? 82.273  100.409 96.169  1.00 4.00  ? 435  GLY A CA  1 
ATOM   3255  C C   . GLY A 1 456 ? 81.072  100.481 97.087  1.00 4.00  ? 435  GLY A C   1 
ATOM   3256  O O   . GLY A 1 456 ? 80.255  99.561  97.105  1.00 4.00  ? 435  GLY A O   1 
ATOM   3257  N N   . VAL A 1 457 ? 80.945  101.561 97.852  1.00 3.04  ? 436  VAL A N   1 
ATOM   3258  C CA  . VAL A 1 457 ? 79.907  101.686 98.872  1.00 3.04  ? 436  VAL A CA  1 
ATOM   3259  C C   . VAL A 1 457 ? 79.231  103.039 98.714  1.00 3.04  ? 436  VAL A C   1 
ATOM   3260  O O   . VAL A 1 457 ? 79.829  104.074 99.025  1.00 3.04  ? 436  VAL A O   1 
ATOM   3261  C CB  . VAL A 1 457 ? 80.467  101.531 100.291 1.00 3.04  ? 436  VAL A CB  1 
ATOM   3262  C CG1 . VAL A 1 457 ? 79.372  101.755 101.313 1.00 3.04  ? 436  VAL A CG1 1 
ATOM   3263  C CG2 . VAL A 1 457 ? 81.092  100.165 100.466 1.00 3.04  ? 436  VAL A CG2 1 
ATOM   3264  N N   . TRP A 1 458 ? 77.986  103.035 98.256  1.00 4.23  ? 437  TRP A N   1 
ATOM   3265  C CA  . TRP A 1 458 ? 77.204  104.254 98.105  1.00 4.23  ? 437  TRP A CA  1 
ATOM   3266  C C   . TRP A 1 458 ? 76.170  104.327 99.219  1.00 4.23  ? 437  TRP A C   1 
ATOM   3267  O O   . TRP A 1 458 ? 75.358  103.413 99.374  1.00 4.23  ? 437  TRP A O   1 
ATOM   3268  C CB  . TRP A 1 458 ? 76.519  104.299 96.743  1.00 4.23  ? 437  TRP A CB  1 
ATOM   3269  C CG  . TRP A 1 458 ? 77.446  104.182 95.609  1.00 4.23  ? 437  TRP A CG  1 
ATOM   3270  C CD1 . TRP A 1 458 ? 78.048  103.054 95.164  1.00 4.23  ? 437  TRP A CD1 1 
ATOM   3271  C CD2 . TRP A 1 458 ? 77.883  105.236 94.753  1.00 4.23  ? 437  TRP A CD2 1 
ATOM   3272  N NE1 . TRP A 1 458 ? 78.839  103.334 94.081  1.00 4.23  ? 437  TRP A NE1 1 
ATOM   3273  C CE2 . TRP A 1 458 ? 78.752  104.672 93.809  1.00 4.23  ? 437  TRP A CE2 1 
ATOM   3274  C CE3 . TRP A 1 458 ? 77.626  106.606 94.698  1.00 4.23  ? 437  TRP A CE3 1 
ATOM   3275  C CZ2 . TRP A 1 458 ? 79.366  105.426 92.822  1.00 4.23  ? 437  TRP A CZ2 1 
ATOM   3276  C CZ3 . TRP A 1 458 ? 78.232  107.350 93.716  1.00 4.23  ? 437  TRP A CZ3 1 
ATOM   3277  C CH2 . TRP A 1 458 ? 79.092  106.761 92.791  1.00 4.23  ? 437  TRP A CH2 1 
ATOM   3278  N N   . SER A 1 459 ? 76.194  105.418 99.973  1.00 6.27  ? 438  SER A N   1 
ATOM   3279  C CA  . SER A 1 459 ? 75.276  105.618 101.083 1.00 6.27  ? 438  SER A CA  1 
ATOM   3280  C C   . SER A 1 459 ? 75.465  107.032 101.601 1.00 6.27  ? 438  SER A C   1 
ATOM   3281  O O   . SER A 1 459 ? 76.484  107.672 101.340 1.00 6.27  ? 438  SER A O   1 
ATOM   3282  C CB  . SER A 1 459 ? 75.511  104.605 102.205 1.00 6.27  ? 438  SER A CB  1 
ATOM   3283  O OG  . SER A 1 459 ? 74.521  104.719 103.210 1.00 6.27  ? 438  SER A OG  1 
ATOM   3284  N N   . ARG A 1 460 ? 74.468  107.513 102.340 1.00 11.75 ? 439  ARG A N   1 
ATOM   3285  C CA  . ARG A 1 460 ? 74.575  108.810 102.986 1.00 11.75 ? 439  ARG A CA  1 
ATOM   3286  C C   . ARG A 1 460 ? 74.831  108.719 104.481 1.00 11.75 ? 439  ARG A C   1 
ATOM   3287  O O   . ARG A 1 460 ? 75.364  109.670 105.054 1.00 11.75 ? 439  ARG A O   1 
ATOM   3288  C CB  . ARG A 1 460 ? 73.311  109.637 102.748 1.00 11.75 ? 439  ARG A CB  1 
ATOM   3289  C CG  . ARG A 1 460 ? 72.791  109.572 101.339 1.00 11.75 ? 439  ARG A CG  1 
ATOM   3290  C CD  . ARG A 1 460 ? 71.569  110.448 101.178 1.00 11.75 ? 439  ARG A CD  1 
ATOM   3291  N NE  . ARG A 1 460 ? 71.072  110.421 99.809  1.00 11.75 ? 439  ARG A NE  1 
ATOM   3292  C CZ  . ARG A 1 460 ? 70.540  111.464 99.188  1.00 11.75 ? 439  ARG A CZ  1 
ATOM   3293  N NH1 . ARG A 1 460 ? 70.432  112.624 99.816  1.00 11.75 ? 439  ARG A NH1 1 
ATOM   3294  N NH2 . ARG A 1 460 ? 70.117  111.345 97.939  1.00 11.75 ? 439  ARG A NH2 1 
ATOM   3295  N N   . ASP A 1 461 ? 74.462  107.616 105.125 1.00 14.76 ? 440  ASP A N   1 
ATOM   3296  C CA  . ASP A 1 461 ? 74.762  107.453 106.540 1.00 14.76 ? 440  ASP A CA  1 
ATOM   3297  C C   . ASP A 1 461 ? 76.270  107.455 106.753 1.00 14.76 ? 440  ASP A C   1 
ATOM   3298  O O   . ASP A 1 461 ? 77.027  106.898 105.955 1.00 14.76 ? 440  ASP A O   1 
ATOM   3299  C CB  . ASP A 1 461 ? 74.144  106.155 107.064 1.00 14.76 ? 440  ASP A CB  1 
ATOM   3300  C CG  . ASP A 1 461 ? 74.281  105.997 108.571 1.00 14.76 ? 440  ASP A CG  1 
ATOM   3301  O OD1 . ASP A 1 461 ? 74.884  106.869 109.228 1.00 14.76 ? 440  ASP A OD1 1 
ATOM   3302  O OD2 . ASP A 1 461 ? 73.777  104.988 109.105 1.00 14.76 ? 440  ASP A OD2 1 
ATOM   3303  N N   . ALA A 1 462 ? 76.708  108.107 107.830 1.00 14.42 ? 441  ALA A N   1 
ATOM   3304  C CA  . ALA A 1 462 ? 78.135  108.191 108.114 1.00 14.42 ? 441  ALA A CA  1 
ATOM   3305  C C   . ALA A 1 462 ? 78.685  106.878 108.655 1.00 14.42 ? 441  ALA A C   1 
ATOM   3306  O O   . ALA A 1 462 ? 79.774  106.451 108.261 1.00 14.42 ? 441  ALA A O   1 
ATOM   3307  C CB  . ALA A 1 462 ? 78.408  109.326 109.099 1.00 14.42 ? 441  ALA A CB  1 
ATOM   3308  N N   . ASN A 1 463 ? 77.951  106.230 109.560 1.00 13.25 ? 442  ASN A N   1 
ATOM   3309  C CA  . ASN A 1 463 ? 78.432  104.981 110.135 1.00 13.25 ? 442  ASN A CA  1 
ATOM   3310  C C   . ASN A 1 463 ? 78.441  103.867 109.102 1.00 13.25 ? 442  ASN A C   1 
ATOM   3311  O O   . ASN A 1 463 ? 79.322  103.001 109.126 1.00 13.25 ? 442  ASN A O   1 
ATOM   3312  C CB  . ASN A 1 463 ? 77.571  104.587 111.332 1.00 13.25 ? 442  ASN A CB  1 
ATOM   3313  C CG  . ASN A 1 463 ? 77.900  105.387 112.570 1.00 13.25 ? 442  ASN A CG  1 
ATOM   3314  O OD1 . ASN A 1 463 ? 78.509  104.875 113.509 1.00 13.25 ? 442  ASN A OD1 1 
ATOM   3315  N ND2 . ASN A 1 463 ? 77.505  106.654 112.580 1.00 13.25 ? 442  ASN A ND2 1 
ATOM   3316  N N   . THR A 1 464 ? 77.452  103.857 108.208 1.00 10.73 ? 443  THR A N   1 
ATOM   3317  C CA  . THR A 1 464 ? 77.343  102.780 107.232 1.00 10.73 ? 443  THR A CA  1 
ATOM   3318  C C   . THR A 1 464 ? 78.552  102.746 106.315 1.00 10.73 ? 443  THR A C   1 
ATOM   3319  O O   . THR A 1 464 ? 79.106  101.676 106.047 1.00 10.73 ? 443  THR A O   1 
ATOM   3320  C CB  . THR A 1 464 ? 76.062  102.937 106.415 1.00 10.73 ? 443  THR A CB  1 
ATOM   3321  O OG1 . THR A 1 464 ? 74.937  102.555 107.213 1.00 10.73 ? 443  THR A OG1 1 
ATOM   3322  C CG2 . THR A 1 464 ? 76.114  102.072 105.172 1.00 10.73 ? 443  THR A CG2 1 
ATOM   3323  N N   . CYS A 1 465 ? 78.988  103.912 105.840 1.00 7.83  ? 444  CYS A N   1 
ATOM   3324  C CA  . CYS A 1 465 ? 80.120  103.957 104.926 1.00 7.83  ? 444  CYS A CA  1 
ATOM   3325  C C   . CYS A 1 465 ? 81.376  103.393 105.576 1.00 7.83  ? 444  CYS A C   1 
ATOM   3326  O O   . CYS A 1 465 ? 82.080  102.576 104.974 1.00 7.83  ? 444  CYS A O   1 
ATOM   3327  C CB  . CYS A 1 465 ? 80.350  105.391 104.455 1.00 7.83  ? 444  CYS A CB  1 
ATOM   3328  S SG  . CYS A 1 465 ? 79.100  106.024 103.314 1.00 7.83  ? 444  CYS A SG  1 
ATOM   3329  N N   . TYR A 1 466 ? 81.655  103.783 106.819 1.00 6.47  ? 445  TYR A N   1 
ATOM   3330  C CA  . TYR A 1 466 ? 82.870  103.307 107.469 1.00 6.47  ? 445  TYR A CA  1 
ATOM   3331  C C   . TYR A 1 466 ? 82.773  101.828 107.819 1.00 6.47  ? 445  TYR A C   1 
ATOM   3332  O O   . TYR A 1 466 ? 83.722  101.070 107.596 1.00 6.47  ? 445  TYR A O   1 
ATOM   3333  C CB  . TYR A 1 466 ? 83.175  104.120 108.720 1.00 6.47  ? 445  TYR A CB  1 
ATOM   3334  C CG  . TYR A 1 466 ? 84.489  103.725 109.354 1.00 6.47  ? 445  TYR A CG  1 
ATOM   3335  C CD1 . TYR A 1 466 ? 85.693  104.080 108.766 1.00 6.47  ? 445  TYR A CD1 1 
ATOM   3336  C CD2 . TYR A 1 466 ? 84.528  102.974 110.512 1.00 6.47  ? 445  TYR A CD2 1 
ATOM   3337  C CE1 . TYR A 1 466 ? 86.894  103.720 109.331 1.00 6.47  ? 445  TYR A CE1 1 
ATOM   3338  C CE2 . TYR A 1 466 ? 85.725  102.617 111.085 1.00 6.47  ? 445  TYR A CE2 1 
ATOM   3339  C CZ  . TYR A 1 466 ? 86.903  102.989 110.491 1.00 6.47  ? 445  TYR A CZ  1 
ATOM   3340  O OH  . TYR A 1 466 ? 88.098  102.623 111.059 1.00 6.47  ? 445  TYR A OH  1 
ATOM   3341  N N   . ARG A 1 467 ? 81.648  101.401 108.400 1.00 7.42  ? 446  ARG A N   1 
ATOM   3342  C CA  . ARG A 1 467 ? 81.484  99.988  108.726 1.00 7.42  ? 446  ARG A CA  1 
ATOM   3343  C C   . ARG A 1 467 ? 81.617  99.120  107.481 1.00 7.42  ? 446  ARG A C   1 
ATOM   3344  O O   . ARG A 1 467 ? 82.230  98.049  107.525 1.00 7.42  ? 446  ARG A O   1 
ATOM   3345  C CB  . ARG A 1 467 ? 80.125  99.759  109.381 1.00 7.42  ? 446  ARG A CB  1 
ATOM   3346  C CG  . ARG A 1 467 ? 79.883  100.422 110.731 1.00 7.42  ? 446  ARG A CG  1 
ATOM   3347  C CD  . ARG A 1 467 ? 80.745  99.890  111.866 1.00 7.42  ? 446  ARG A CD  1 
ATOM   3348  N NE  . ARG A 1 467 ? 82.056  100.505 112.002 1.00 7.42  ? 446  ARG A NE  1 
ATOM   3349  C CZ  . ARG A 1 467 ? 83.020  100.004 112.766 1.00 7.42  ? 446  ARG A CZ  1 
ATOM   3350  N NH1 . ARG A 1 467 ? 82.801  98.900  113.460 1.00 7.42  ? 446  ARG A NH1 1 
ATOM   3351  N NH2 . ARG A 1 467 ? 84.192  100.607 112.853 1.00 7.42  ? 446  ARG A NH2 1 
ATOM   3352  N N   . MET A 1 468 ? 81.065  99.574  106.355 1.00 7.74  ? 447  MET A N   1 
ATOM   3353  C CA  . MET A 1 468 ? 81.093  98.773  105.142 1.00 7.74  ? 447  MET A CA  1 
ATOM   3354  C C   . MET A 1 468 ? 82.472  98.796  104.503 1.00 7.74  ? 447  MET A C   1 
ATOM   3355  O O   . MET A 1 468 ? 82.868  97.824  103.857 1.00 7.74  ? 447  MET A O   1 
ATOM   3356  C CB  . MET A 1 468 ? 80.040  99.294  104.165 1.00 7.74  ? 447  MET A CB  1 
ATOM   3357  C CG  . MET A 1 468 ? 78.615  98.831  104.454 1.00 7.74  ? 447  MET A CG  1 
ATOM   3358  S SD  . MET A 1 468 ? 78.135  97.183  103.932 1.00 7.74  ? 447  MET A SD  1 
ATOM   3359  C CE  . MET A 1 468 ? 79.080  96.975  102.438 1.00 7.74  ? 447  MET A CE  1 
ATOM   3360  N N   . GLY A 1 469 ? 83.216  99.892  104.665 1.00 5.24  ? 448  GLY A N   1 
ATOM   3361  C CA  . GLY A 1 469 ? 84.566  99.936  104.130 1.00 5.24  ? 448  GLY A CA  1 
ATOM   3362  C C   . GLY A 1 469 ? 85.557  99.145  104.960 1.00 5.24  ? 448  GLY A C   1 
ATOM   3363  O O   . GLY A 1 469 ? 86.540  98.618  104.436 1.00 5.24  ? 448  GLY A O   1 
ATOM   3364  N N   . ARG A 1 470 ? 85.332  99.077  106.268 1.00 4.90  ? 449  ARG A N   1 
ATOM   3365  C CA  . ARG A 1 470 ? 86.178  98.261  107.129 1.00 4.90  ? 449  ARG A CA  1 
ATOM   3366  C C   . ARG A 1 470 ? 85.839  96.784  106.995 1.00 4.90  ? 449  ARG A C   1 
ATOM   3367  O O   . ARG A 1 470 ? 86.737  95.937  107.006 1.00 4.90  ? 449  ARG A O   1 
ATOM   3368  C CB  . ARG A 1 470 ? 86.032  98.728  108.577 1.00 4.90  ? 449  ARG A CB  1 
ATOM   3369  C CG  . ARG A 1 470 ? 86.454  100.165 108.755 1.00 4.90  ? 449  ARG A CG  1 
ATOM   3370  C CD  . ARG A 1 470 ? 87.945  100.332 108.581 1.00 4.90  ? 449  ARG A CD  1 
ATOM   3371  N NE  . ARG A 1 470 ? 88.670  99.756  109.704 1.00 4.90  ? 449  ARG A NE  1 
ATOM   3372  C CZ  . ARG A 1 470 ? 89.938  99.380  109.661 1.00 4.90  ? 449  ARG A CZ  1 
ATOM   3373  N NH1 . ARG A 1 470 ? 90.612  99.472  108.531 1.00 4.90  ? 449  ARG A NH1 1 
ATOM   3374  N NH2 . ARG A 1 470 ? 90.519  98.874  110.734 1.00 4.90  ? 449  ARG A NH2 1 
ATOM   3375  N N   . GLY A 1 471 ? 84.552  96.462  106.864 1.00 5.77  ? 450  GLY A N   1 
ATOM   3376  C CA  . GLY A 1 471 ? 84.152  95.071  106.751 1.00 5.77  ? 450  GLY A CA  1 
ATOM   3377  C C   . GLY A 1 471 ? 84.573  94.426  105.446 1.00 5.77  ? 450  GLY A C   1 
ATOM   3378  O O   . GLY A 1 471 ? 85.023  93.278  105.432 1.00 5.77  ? 450  GLY A O   1 
ATOM   3379  N N   . ILE A 1 472 ? 84.438  95.147  104.335 1.00 6.73  ? 451  ILE A N   1 
ATOM   3380  C CA  . ILE A 1 472 ? 84.654  94.538  103.027 1.00 6.73  ? 451  ILE A CA  1 
ATOM   3381  C C   . ILE A 1 472 ? 86.125  94.186  102.872 1.00 6.73  ? 451  ILE A C   1 
ATOM   3382  O O   . ILE A 1 472 ? 87.003  95.047  102.994 1.00 6.73  ? 451  ILE A O   1 
ATOM   3383  C CB  . ILE A 1 472 ? 84.191  95.462  101.897 1.00 6.73  ? 451  ILE A CB  1 
ATOM   3384  C CG1 . ILE A 1 472 ? 82.673  95.485  101.798 1.00 6.73  ? 451  ILE A CG1 1 
ATOM   3385  C CG2 . ILE A 1 472 ? 84.723  94.981  100.585 1.00 6.73  ? 451  ILE A CG2 1 
ATOM   3386  C CD1 . ILE A 1 472 ? 82.175  96.611  100.946 1.00 6.73  ? 451  ILE A CD1 1 
ATOM   3387  N N   . LYS A 1 473 ? 86.397  92.913  102.591 1.00 9.70  ? 452  LYS A N   1 
ATOM   3388  C CA  . LYS A 1 473 ? 87.757  92.429  102.379 1.00 9.70  ? 452  LYS A CA  1 
ATOM   3389  C C   . LYS A 1 473 ? 88.218  92.833  100.981 1.00 9.70  ? 452  LYS A C   1 
ATOM   3390  O O   . LYS A 1 473 ? 88.364  92.018  100.071 1.00 9.70  ? 452  LYS A O   1 
ATOM   3391  C CB  . LYS A 1 473 ? 87.815  90.922  102.571 1.00 9.70  ? 452  LYS A CB  1 
ATOM   3392  C CG  . LYS A 1 473 ? 87.819  90.485  104.018 1.00 9.70  ? 452  LYS A CG  1 
ATOM   3393  C CD  . LYS A 1 473 ? 87.589  88.993  104.136 1.00 9.70  ? 452  LYS A CD  1 
ATOM   3394  C CE  . LYS A 1 473 ? 86.836  88.649  105.413 1.00 9.70  ? 452  LYS A CE  1 
ATOM   3395  N NZ  . LYS A 1 473 ? 85.497  89.296  105.476 1.00 9.70  ? 452  LYS A NZ  1 
ATOM   3396  N N   . ALA A 1 474 ? 88.448  94.129  100.816 1.00 7.24  ? 453  ALA A N   1 
ATOM   3397  C CA  . ALA A 1 474 ? 88.896  94.676  99.547  1.00 7.24  ? 453  ALA A CA  1 
ATOM   3398  C C   . ALA A 1 474 ? 90.077  95.604  99.776  1.00 7.24  ? 453  ALA A C   1 
ATOM   3399  O O   . ALA A 1 474 ? 90.094  96.374  100.739 1.00 7.24  ? 453  ALA A O   1 
ATOM   3400  C CB  . ALA A 1 474 ? 87.773  95.426  98.831  1.00 7.24  ? 453  ALA A CB  1 
ATOM   3401  N N   . GLY A 1 475 ? 91.066  95.525  98.886  1.00 6.84  ? 454  GLY A N   1 
ATOM   3402  C CA  . GLY A 1 475 ? 92.234  96.377  99.029  1.00 6.84  ? 454  GLY A CA  1 
ATOM   3403  C C   . GLY A 1 475 ? 91.876  97.848  98.974  1.00 6.84  ? 454  GLY A C   1 
ATOM   3404  O O   . GLY A 1 475 ? 92.347  98.648  99.784  1.00 6.84  ? 454  GLY A O   1 
ATOM   3405  N N   . ARG A 1 476 ? 91.026  98.218  98.021  1.00 5.08  ? 455  ARG A N   1 
ATOM   3406  C CA  . ARG A 1 476 ? 90.502  99.566  97.899  1.00 5.08  ? 455  ARG A CA  1 
ATOM   3407  C C   . ARG A 1 476 ? 88.991  99.530  98.049  1.00 5.08  ? 455  ARG A C   1 
ATOM   3408  O O   . ARG A 1 476 ? 88.326  98.664  97.479  1.00 5.08  ? 455  ARG A O   1 
ATOM   3409  C CB  . ARG A 1 476 ? 90.861  100.187 96.555  1.00 5.08  ? 455  ARG A CB  1 
ATOM   3410  C CG  . ARG A 1 476 ? 90.455  101.637 96.457  1.00 5.08  ? 455  ARG A CG  1 
ATOM   3411  C CD  . ARG A 1 476 ? 90.690  102.189 95.080  1.00 5.08  ? 455  ARG A CD  1 
ATOM   3412  N NE  . ARG A 1 476 ? 92.075  102.343 94.657  1.00 5.08  ? 455  ARG A NE  1 
ATOM   3413  C CZ  . ARG A 1 476 ? 92.690  103.512 94.568  1.00 5.08  ? 455  ARG A CZ  1 
ATOM   3414  N NH1 . ARG A 1 476 ? 92.043  104.614 94.877  1.00 5.08  ? 455  ARG A NH1 1 
ATOM   3415  N NH2 . ARG A 1 476 ? 93.943  103.583 94.159  1.00 5.08  ? 455  ARG A NH2 1 
ATOM   3416  N N   . VAL A 1 477 ? 88.453  100.464 98.822  1.00 4.11  ? 456  VAL A N   1 
ATOM   3417  C CA  . VAL A 1 477 ? 87.015  100.639 98.969  1.00 4.11  ? 456  VAL A CA  1 
ATOM   3418  C C   . VAL A 1 477 ? 86.683  102.076 98.602  1.00 4.11  ? 456  VAL A C   1 
ATOM   3419  O O   . VAL A 1 477 ? 87.133  103.011 99.272  1.00 4.11  ? 456  VAL A O   1 
ATOM   3420  C CB  . VAL A 1 477 ? 86.541  100.322 100.395 1.00 4.11  ? 456  VAL A CB  1 
ATOM   3421  C CG1 . VAL A 1 477 ? 85.081  100.690 100.560 1.00 4.11  ? 456  VAL A CG1 1 
ATOM   3422  C CG2 . VAL A 1 477 ? 86.759  98.863  100.713 1.00 4.11  ? 456  VAL A CG2 1 
ATOM   3423  N N   . TRP A 1 478 ? 85.899  102.252 97.546  1.00 10.72 ? 457  TRP A N   1 
ATOM   3424  C CA  . TRP A 1 478 ? 85.397  103.561 97.152  1.00 10.72 ? 457  TRP A CA  1 
ATOM   3425  C C   . TRP A 1 478 ? 84.109  103.853 97.906  1.00 10.72 ? 457  TRP A C   1 
ATOM   3426  O O   . TRP A 1 478 ? 83.164  103.064 97.846  1.00 10.72 ? 457  TRP A O   1 
ATOM   3427  C CB  . TRP A 1 478 ? 85.129  103.602 95.654  1.00 10.72 ? 457  TRP A CB  1 
ATOM   3428  C CG  . TRP A 1 478 ? 86.308  103.694 94.771  1.00 10.72 ? 457  TRP A CG  1 
ATOM   3429  C CD1 . TRP A 1 478 ? 86.998  104.816 94.453  1.00 10.72 ? 457  TRP A CD1 1 
ATOM   3430  C CD2 . TRP A 1 478 ? 86.917  102.627 94.043  1.00 10.72 ? 457  TRP A CD2 1 
ATOM   3431  N NE1 . TRP A 1 478 ? 88.010  104.518 93.580  1.00 10.72 ? 457  TRP A NE1 1 
ATOM   3432  C CE2 . TRP A 1 478 ? 87.980  103.177 93.312  1.00 10.72 ? 457  TRP A CE2 1 
ATOM   3433  C CE3 . TRP A 1 478 ? 86.677  101.258 93.950  1.00 10.72 ? 457  TRP A CE3 1 
ATOM   3434  C CZ2 . TRP A 1 478 ? 88.789  102.410 92.489  1.00 10.72 ? 457  TRP A CZ2 1 
ATOM   3435  C CZ3 . TRP A 1 478 ? 87.482  100.499 93.135  1.00 10.72 ? 457  TRP A CZ3 1 
ATOM   3436  C CH2 . TRP A 1 478 ? 88.529  101.073 92.422  1.00 10.72 ? 457  TRP A CH2 1 
ATOM   3437  N N   . THR A 1 479 ? 84.059  104.981 98.601  1.00 3.22  ? 458  THR A N   1 
ATOM   3438  C CA  . THR A 1 479 ? 82.851  105.412 99.291  1.00 3.22  ? 458  THR A CA  1 
ATOM   3439  C C   . THR A 1 479 ? 82.254  106.601 98.550  1.00 3.22  ? 458  THR A C   1 
ATOM   3440  O O   . THR A 1 479 ? 82.917  107.629 98.394  1.00 3.22  ? 458  THR A O   1 
ATOM   3441  C CB  . THR A 1 479 ? 83.142  105.787 100.741 1.00 3.22  ? 458  THR A CB  1 
ATOM   3442  O OG1 . THR A 1 479 ? 83.337  104.601 101.521 1.00 3.22  ? 458  THR A OG1 1 
ATOM   3443  C CG2 . THR A 1 479 ? 81.989  106.563 101.319 1.00 3.22  ? 458  THR A CG2 1 
ATOM   3444  N N   . ASN A 1 480 ? 81.012  106.452 98.089  1.00 3.52  ? 459  ASN A N   1 
ATOM   3445  C CA  . ASN A 1 480 ? 80.236  107.512 97.446  1.00 3.52  ? 459  ASN A CA  1 
ATOM   3446  C C   . ASN A 1 480 ? 80.888  108.033 96.178  1.00 3.52  ? 459  ASN A C   1 
ATOM   3447  O O   . ASN A 1 480 ? 80.560  109.123 95.713  1.00 3.52  ? 459  ASN A O   1 
ATOM   3448  C CB  . ASN A 1 480 ? 79.966  108.668 98.408  1.00 3.52  ? 459  ASN A CB  1 
ATOM   3449  C CG  . ASN A 1 480 ? 78.940  108.318 99.448  1.00 3.52  ? 459  ASN A CG  1 
ATOM   3450  O OD1 . ASN A 1 480 ? 78.441  107.200 99.481  1.00 3.52  ? 459  ASN A OD1 1 
ATOM   3451  N ND2 . ASN A 1 480 ? 78.611  109.273 100.302 1.00 3.52  ? 459  ASN A ND2 1 
ATOM   3452  N N   . CYS A 1 481 ? 81.811  107.267 95.617  1.00 4.24  ? 460  CYS A N   1 
ATOM   3453  C CA  . CYS A 1 481 ? 82.329  107.484 94.279  1.00 4.24  ? 460  CYS A CA  1 
ATOM   3454  C C   . CYS A 1 481 ? 82.717  106.119 93.758  1.00 4.24  ? 460  CYS A C   1 
ATOM   3455  O O   . CYS A 1 481 ? 82.543  105.113 94.446  1.00 4.24  ? 460  CYS A O   1 
ATOM   3456  C CB  . CYS A 1 481 ? 83.529  108.424 94.266  1.00 4.24  ? 460  CYS A CB  1 
ATOM   3457  S SG  . CYS A 1 481 ? 84.935  107.840 95.243  1.00 4.24  ? 460  CYS A SG  1 
ATOM   3458  N N   . TYR A 1 482 ? 83.254  106.068 92.546  1.00 6.52  ? 461  TYR A N   1 
ATOM   3459  C CA  . TYR A 1 482 ? 83.829  104.795 92.163  1.00 6.52  ? 461  TYR A CA  1 
ATOM   3460  C C   . TYR A 1 482 ? 84.711  105.103 90.960  1.00 6.52  ? 461  TYR A C   1 
ATOM   3461  O O   . TYR A 1 482 ? 84.569  106.159 90.339  1.00 6.52  ? 461  TYR A O   1 
ATOM   3462  C CB  . TYR A 1 482 ? 82.730  103.782 91.824  1.00 6.52  ? 461  TYR A CB  1 
ATOM   3463  C CG  . TYR A 1 482 ? 83.199  102.367 91.756  1.00 6.52  ? 461  TYR A CG  1 
ATOM   3464  C CD1 . TYR A 1 482 ? 83.430  101.673 92.933  1.00 6.52  ? 461  TYR A CD1 1 
ATOM   3465  C CD2 . TYR A 1 482 ? 83.522  101.761 90.580  1.00 6.52  ? 461  TYR A CD2 1 
ATOM   3466  C CE1 . TYR A 1 482 ? 83.858  100.393 92.933  1.00 6.52  ? 461  TYR A CE1 1 
ATOM   3467  C CE2 . TYR A 1 482 ? 83.996  100.479 90.577  1.00 6.52  ? 461  TYR A CE2 1 
ATOM   3468  C CZ  . TYR A 1 482 ? 84.159  99.798  91.756  1.00 6.52  ? 461  TYR A CZ  1 
ATOM   3469  O OH  . TYR A 1 482 ? 84.617  98.510  91.770  1.00 6.52  ? 461  TYR A OH  1 
ATOM   3470  N N   . HIS A 1 483 ? 85.620  104.186 90.632  1.00 8.32  ? 462  HIS A N   1 
ATOM   3471  C CA  . HIS A 1 483 ? 86.608  104.405 89.569  1.00 8.32  ? 462  HIS A CA  1 
ATOM   3472  C C   . HIS A 1 483 ? 87.338  105.733 89.722  1.00 8.32  ? 462  HIS A C   1 
ATOM   3473  O O   . HIS A 1 483 ? 87.357  106.566 88.814  1.00 8.32  ? 462  HIS A O   1 
ATOM   3474  C CB  . HIS A 1 483 ? 86.002  104.329 88.170  1.00 8.32  ? 462  HIS A CB  1 
ATOM   3475  C CG  . HIS A 1 483 ? 85.954  102.951 87.592  1.00 8.32  ? 462  HIS A CG  1 
ATOM   3476  N ND1 . HIS A 1 483 ? 84.801  102.202 87.540  1.00 8.32  ? 462  HIS A ND1 1 
ATOM   3477  C CD2 . HIS A 1 483 ? 86.931  102.179 87.059  1.00 8.32  ? 462  HIS A CD2 1 
ATOM   3478  C CE1 . HIS A 1 483 ? 85.064  101.035 86.980  1.00 8.32  ? 462  HIS A CE1 1 
ATOM   3479  N NE2 . HIS A 1 483 ? 86.350  100.994 86.684  1.00 8.32  ? 462  HIS A NE2 1 
ATOM   3480  N N   . ALA A 1 484 ? 87.942  105.939 90.881  1.00 6.64  ? 463  ALA A N   1 
ATOM   3481  C CA  . ALA A 1 484 ? 88.863  107.048 91.088  1.00 6.64  ? 463  ALA A CA  1 
ATOM   3482  C C   . ALA A 1 484 ? 90.248  106.458 91.324  1.00 6.64  ? 463  ALA A C   1 
ATOM   3483  O O   . ALA A 1 484 ? 90.466  105.757 92.317  1.00 6.64  ? 463  ALA A O   1 
ATOM   3484  C CB  . ALA A 1 484 ? 88.419  107.919 92.257  1.00 6.64  ? 463  ALA A CB  1 
ATOM   3485  N N   . TYR A 1 485 ? 91.183  106.745 90.423  1.00 6.31  ? 464  TYR A N   1 
ATOM   3486  C CA  . TYR A 1 485 ? 92.541  106.235 90.572  1.00 6.31  ? 464  TYR A CA  1 
ATOM   3487  C C   . TYR A 1 485 ? 93.556  107.359 90.738  1.00 6.31  ? 464  TYR A C   1 
ATOM   3488  O O   . TYR A 1 485 ? 94.528  107.417 89.977  1.00 6.31  ? 464  TYR A O   1 
ATOM   3489  C CB  . TYR A 1 485 ? 92.942  105.398 89.359  1.00 6.31  ? 464  TYR A CB  1 
ATOM   3490  C CG  . TYR A 1 485 ? 92.205  104.094 89.212  1.00 6.31  ? 464  TYR A CG  1 
ATOM   3491  C CD1 . TYR A 1 485 ? 91.868  103.339 90.323  1.00 6.31  ? 464  TYR A CD1 1 
ATOM   3492  C CD2 . TYR A 1 485 ? 91.859  103.611 87.958  1.00 6.31  ? 464  TYR A CD2 1 
ATOM   3493  C CE1 . TYR A 1 485 ? 91.201  102.146 90.192  1.00 6.31  ? 464  TYR A CE1 1 
ATOM   3494  C CE2 . TYR A 1 485 ? 91.192  102.418 87.817  1.00 6.31  ? 464  TYR A CE2 1 
ATOM   3495  C CZ  . TYR A 1 485 ? 90.864  101.688 88.940  1.00 6.31  ? 464  TYR A CZ  1 
ATOM   3496  O OH  . TYR A 1 485 ? 90.197  100.493 88.812  1.00 6.31  ? 464  TYR A OH  1 
ATOM   3497  N N   . PRO A 1 486 ? 93.400  108.252 91.717  1.00 3.72  ? 465  PRO A N   1 
ATOM   3498  C CA  . PRO A 1 486 ? 94.366  109.347 91.844  1.00 3.72  ? 465  PRO A CA  1 
ATOM   3499  C C   . PRO A 1 486 ? 95.661  108.830 92.449  1.00 3.72  ? 465  PRO A C   1 
ATOM   3500  O O   . PRO A 1 486 ? 95.649  108.168 93.489  1.00 3.72  ? 465  PRO A O   1 
ATOM   3501  C CB  . PRO A 1 486 ? 93.659  110.332 92.777  1.00 3.72  ? 465  PRO A CB  1 
ATOM   3502  C CG  . PRO A 1 486 ? 92.804  109.478 93.629  1.00 3.72  ? 465  PRO A CG  1 
ATOM   3503  C CD  . PRO A 1 486 ? 92.468  108.228 92.858  1.00 3.72  ? 465  PRO A CD  1 
ATOM   3504  N N   . ALA A 1 487 ? 96.778  109.103 91.774  1.00 2.46  ? 466  ALA A N   1 
ATOM   3505  C CA  . ALA A 1 487 ? 98.090  108.832 92.341  1.00 2.46  ? 466  ALA A CA  1 
ATOM   3506  C C   . ALA A 1 487 ? 98.152  109.356 93.765  1.00 2.46  ? 466  ALA A C   1 
ATOM   3507  O O   . ALA A 1 487 ? 97.548  110.383 94.081  1.00 2.46  ? 466  ALA A O   1 
ATOM   3508  C CB  . ALA A 1 487 ? 99.182  109.481 91.490  1.00 2.46  ? 466  ALA A CB  1 
ATOM   3509  N N   . HIS A 1 488 ? 98.881  108.632 94.617  1.00 2.53  ? 467  HIS A N   1 
ATOM   3510  C CA  . HIS A 1 488 ? 99.008  108.864 96.058  1.00 2.53  ? 467  HIS A CA  1 
ATOM   3511  C C   . HIS A 1 488 ? 97.824  108.303 96.840  1.00 2.53  ? 467  HIS A C   1 
ATOM   3512  O O   . HIS A 1 488 ? 97.573  108.711 97.976  1.00 2.53  ? 467  HIS A O   1 
ATOM   3513  C CB  . HIS A 1 488 ? 99.218  110.354 96.358  1.00 2.53  ? 467  HIS A CB  1 
ATOM   3514  C CG  . HIS A 1 488 ? 99.721  110.646 97.733  1.00 2.53  ? 467  HIS A CG  1 
ATOM   3515  N ND1 . HIS A 1 488 ? 100.966 110.245 98.165  1.00 2.53  ? 467  HIS A ND1 1 
ATOM   3516  C CD2 . HIS A 1 488 ? 99.208  111.406 98.725  1.00 2.53  ? 467  HIS A CD2 1 
ATOM   3517  C CE1 . HIS A 1 488 ? 101.161 110.675 99.397  1.00 2.53  ? 467  HIS A CE1 1 
ATOM   3518  N NE2 . HIS A 1 488 ? 100.110 111.386 99.759  1.00 2.53  ? 467  HIS A NE2 1 
ATOM   3519  N N   . ALA A 1 489 ? 97.087  107.367 96.248  1.00 4.08  ? 468  ALA A N   1 
ATOM   3520  C CA  . ALA A 1 489 ? 96.150  106.508 96.960  1.00 4.08  ? 468  ALA A CA  1 
ATOM   3521  C C   . ALA A 1 489 ? 96.521  105.057 96.680  1.00 4.08  ? 468  ALA A C   1 
ATOM   3522  O O   . ALA A 1 489 ? 96.677  104.670 95.518  1.00 4.08  ? 468  ALA A O   1 
ATOM   3523  C CB  . ALA A 1 489 ? 94.710  106.787 96.535  1.00 4.08  ? 468  ALA A CB  1 
ATOM   3524  N N   . ALA A 1 490 ? 96.670  104.262 97.738  1.00 5.15  ? 469  ALA A N   1 
ATOM   3525  C CA  . ALA A 1 490 ? 97.151  102.893 97.595  1.00 5.15  ? 469  ALA A CA  1 
ATOM   3526  C C   . ALA A 1 490 ? 96.113  102.011 96.913  1.00 5.15  ? 469  ALA A C   1 
ATOM   3527  O O   . ALA A 1 490 ? 94.910  102.265 96.976  1.00 5.15  ? 469  ALA A O   1 
ATOM   3528  C CB  . ALA A 1 490 ? 97.513  102.309 98.957  1.00 5.15  ? 469  ALA A CB  1 
ATOM   3529  N N   . PHE A 1 491 ? 96.592  100.950 96.269  1.00 9.59  ? 470  PHE A N   1 
ATOM   3530  C CA  . PHE A 1 491 ? 95.765  100.139 95.381  1.00 9.59  ? 470  PHE A CA  1 
ATOM   3531  C C   . PHE A 1 491 ? 96.345  98.736  95.305  1.00 9.59  ? 470  PHE A C   1 
ATOM   3532  O O   . PHE A 1 491 ? 97.465  98.559  94.820  1.00 9.59  ? 470  PHE A O   1 
ATOM   3533  C CB  . PHE A 1 491 ? 95.705  100.771 93.987  1.00 9.59  ? 470  PHE A CB  1 
ATOM   3534  C CG  . PHE A 1 491 ? 94.659  100.186 93.098  1.00 9.59  ? 470  PHE A CG  1 
ATOM   3535  C CD1 . PHE A 1 491 ? 93.627  99.433  93.618  1.00 9.59  ? 470  PHE A CD1 1 
ATOM   3536  C CD2 . PHE A 1 491 ? 94.710  100.389 91.733  1.00 9.59  ? 470  PHE A CD2 1 
ATOM   3537  C CE1 . PHE A 1 491 ? 92.670  98.892  92.794  1.00 9.59  ? 470  PHE A CE1 1 
ATOM   3538  C CE2 . PHE A 1 491 ? 93.753  99.850  90.902  1.00 9.59  ? 470  PHE A CE2 1 
ATOM   3539  C CZ  . PHE A 1 491 ? 92.735  99.102  91.433  1.00 9.59  ? 470  PHE A CZ  1 
ATOM   3540  N N   . GLY A 1 492 ? 95.587  97.743  95.762  1.00 12.70 ? 471  GLY A N   1 
ATOM   3541  C CA  . GLY A 1 492 ? 96.097  96.383  95.770  1.00 12.70 ? 471  GLY A CA  1 
ATOM   3542  C C   . GLY A 1 492 ? 95.004  95.368  96.016  1.00 12.70 ? 471  GLY A C   1 
ATOM   3543  O O   . GLY A 1 492 ? 93.862  95.711  96.331  1.00 12.70 ? 471  GLY A O   1 
ATOM   3544  N N   . GLY A 1 493 ? 95.381  94.098  95.867  1.00 16.03 ? 472  GLY A N   1 
ATOM   3545  C CA  . GLY A 1 493 ? 94.469  92.985  96.059  1.00 16.03 ? 472  GLY A CA  1 
ATOM   3546  C C   . GLY A 1 493 ? 94.538  92.435  97.466  1.00 16.03 ? 472  GLY A C   1 
ATOM   3547  O O   . GLY A 1 493 ? 95.631  92.243  98.006  1.00 16.03 ? 472  GLY A O   1 
ATOM   3548  N N   . TYR A 1 494 ? 93.381  92.164  98.066  1.00 12.57 ? 473  TYR A N   1 
ATOM   3549  C CA  . TYR A 1 494 ? 93.283  92.028  99.512  1.00 12.57 ? 473  TYR A CA  1 
ATOM   3550  C C   . TYR A 1 494 ? 93.118  90.587  99.969  1.00 12.57 ? 473  TYR A C   1 
ATOM   3551  O O   . TYR A 1 494 ? 93.493  90.268  101.101 1.00 12.57 ? 473  TYR A O   1 
ATOM   3552  C CB  . TYR A 1 494 ? 92.104  92.849  100.013 1.00 12.57 ? 473  TYR A CB  1 
ATOM   3553  C CG  . TYR A 1 494 ? 92.059  93.116  101.491 1.00 12.57 ? 473  TYR A CG  1 
ATOM   3554  C CD1 . TYR A 1 494 ? 92.791  94.162  102.035 1.00 12.57 ? 473  TYR A CD1 1 
ATOM   3555  C CD2 . TYR A 1 494 ? 91.281  92.349  102.338 1.00 12.57 ? 473  TYR A CD2 1 
ATOM   3556  C CE1 . TYR A 1 494 ? 92.747  94.438  103.374 1.00 12.57 ? 473  TYR A CE1 1 
ATOM   3557  C CE2 . TYR A 1 494 ? 91.236  92.614  103.688 1.00 12.57 ? 473  TYR A CE2 1 
ATOM   3558  C CZ  . TYR A 1 494 ? 91.971  93.662  104.198 1.00 12.57 ? 473  TYR A CZ  1 
ATOM   3559  O OH  . TYR A 1 494 ? 91.940  93.932  105.543 1.00 12.57 ? 473  TYR A OH  1 
ATOM   3560  N N   . LYS A 1 495 ? 92.557  89.714  99.133  1.00 18.77 ? 474  LYS A N   1 
ATOM   3561  C CA  . LYS A 1 495 ? 92.441  88.310  99.507  1.00 18.77 ? 474  LYS A CA  1 
ATOM   3562  C C   . LYS A 1 495 ? 93.326  87.418  98.650  1.00 18.77 ? 474  LYS A C   1 
ATOM   3563  O O   . LYS A 1 495 ? 94.238  86.762  99.162  1.00 18.77 ? 474  LYS A O   1 
ATOM   3564  C CB  . LYS A 1 495 ? 90.991  87.841  99.376  1.00 18.77 ? 474  LYS A CB  1 
ATOM   3565  C CG  . LYS A 1 495 ? 90.060  88.296  100.472 1.00 18.77 ? 474  LYS A CG  1 
ATOM   3566  C CD  . LYS A 1 495 ? 89.046  87.210  100.780 1.00 18.77 ? 474  LYS A CD  1 
ATOM   3567  C CE  . LYS A 1 495 ? 88.139  86.956  99.591  1.00 18.77 ? 474  LYS A CE  1 
ATOM   3568  N NZ  . LYS A 1 495 ? 87.248  88.113  99.316  1.00 18.77 ? 474  LYS A NZ  1 
ATOM   3569  N N   . GLN A 1 496 ? 93.065  87.388  97.346  1.00 25.53 ? 475  GLN A N   1 
ATOM   3570  C CA  . GLN A 1 496 ? 93.751  86.485  96.434  1.00 25.53 ? 475  GLN A CA  1 
ATOM   3571  C C   . GLN A 1 496 ? 94.019  87.139  95.078  1.00 25.53 ? 475  GLN A C   1 
ATOM   3572  O O   . GLN A 1 496 ? 94.538  86.491  94.164  1.00 25.53 ? 475  GLN A O   1 
ATOM   3573  C CB  . GLN A 1 496 ? 92.928  85.199  96.297  1.00 25.53 ? 475  GLN A CB  1 
ATOM   3574  C CG  . GLN A 1 496 ? 93.550  84.063  95.501  1.00 25.53 ? 475  GLN A CG  1 
ATOM   3575  C CD  . GLN A 1 496 ? 92.684  82.821  95.505  1.00 25.53 ? 475  GLN A CD  1 
ATOM   3576  O OE1 . GLN A 1 496 ? 93.051  81.793  94.936  1.00 25.53 ? 475  GLN A OE1 1 
ATOM   3577  N NE2 . GLN A 1 496 ? 91.525  82.910  96.150  1.00 25.53 ? 475  GLN A NE2 1 
ATOM   3578  N N   . SER A 1 497 ? 93.697  88.422  94.941  1.00 20.34 ? 476  SER A N   1 
ATOM   3579  C CA  . SER A 1 497 ? 93.754  89.112  93.662  1.00 20.34 ? 476  SER A CA  1 
ATOM   3580  C C   . SER A 1 497 ? 95.017  89.950  93.480  1.00 20.34 ? 476  SER A C   1 
ATOM   3581  O O   . SER A 1 497 ? 94.983  90.943  92.747  1.00 20.34 ? 476  SER A O   1 
ATOM   3582  C CB  . SER A 1 497 ? 92.517  89.993  93.501  1.00 20.34 ? 476  SER A CB  1 
ATOM   3583  O OG  . SER A 1 497 ? 92.411  90.909  94.572  1.00 20.34 ? 476  SER A OG  1 
ATOM   3584  N N   . GLY A 1 498 ? 96.121  89.582  94.121  1.00 19.89 ? 477  GLY A N   1 
ATOM   3585  C CA  . GLY A 1 498 ? 97.389  90.250  93.925  1.00 19.89 ? 477  GLY A CA  1 
ATOM   3586  C C   . GLY A 1 498 ? 98.130  90.462  95.226  1.00 19.89 ? 477  GLY A C   1 
ATOM   3587  O O   . GLY A 1 498 ? 97.645  90.155  96.313  1.00 19.89 ? 477  GLY A O   1 
ATOM   3588  N N   . ILE A 1 499 ? 99.344  90.998  95.094  1.00 17.26 ? 478  ILE A N   1 
ATOM   3589  C CA  . ILE A 1 499 ? 100.217 91.293  96.226  1.00 17.26 ? 478  ILE A CA  1 
ATOM   3590  C C   . ILE A 1 499 ? 100.798 92.689  96.037  1.00 17.26 ? 478  ILE A C   1 
ATOM   3591  O O   . ILE A 1 499 ? 101.153 93.078  94.920  1.00 17.26 ? 478  ILE A O   1 
ATOM   3592  C CB  . ILE A 1 499 ? 101.352 90.255  96.371  1.00 17.26 ? 478  ILE A CB  1 
ATOM   3593  C CG1 . ILE A 1 499 ? 100.809 88.828  96.303  1.00 17.26 ? 478  ILE A CG1 1 
ATOM   3594  C CG2 . ILE A 1 499 ? 102.083 90.448  97.687  1.00 17.26 ? 478  ILE A CG2 1 
ATOM   3595  C CD1 . ILE A 1 499 ? 101.887 87.774  96.231  1.00 17.26 ? 478  ILE A CD1 1 
ATOM   3596  N N   . GLY A 1 500 ? 100.891 93.445  97.128  1.00 13.51 ? 479  GLY A N   1 
ATOM   3597  C CA  . GLY A 1 500 ? 101.470 94.776  97.099  1.00 13.51 ? 479  GLY A CA  1 
ATOM   3598  C C   . GLY A 1 500 ? 100.431 95.862  96.880  1.00 13.51 ? 479  GLY A C   1 
ATOM   3599  O O   . GLY A 1 500 ? 99.222  95.621  96.800  1.00 13.51 ? 479  GLY A O   1 
ATOM   3600  N N   . ARG A 1 501 ? 100.934 97.091  96.783  1.00 9.31  ? 480  ARG A N   1 
ATOM   3601  C CA  . ARG A 1 501 ? 100.110 98.266  96.549  1.00 9.31  ? 480  ARG A CA  1 
ATOM   3602  C C   . ARG A 1 501 ? 100.691 99.076  95.398  1.00 9.31  ? 480  ARG A C   1 
ATOM   3603  O O   . ARG A 1 501 ? 101.901 99.065  95.164  1.00 9.31  ? 480  ARG A O   1 
ATOM   3604  C CB  . ARG A 1 501 ? 100.001 99.139  97.809  1.00 9.31  ? 480  ARG A CB  1 
ATOM   3605  C CG  . ARG A 1 501 ? 99.133  98.543  98.908  1.00 9.31  ? 480  ARG A CG  1 
ATOM   3606  C CD  . ARG A 1 501 ? 97.726  98.254  98.408  1.00 9.31  ? 480  ARG A CD  1 
ATOM   3607  N NE  . ARG A 1 501 ? 96.933  97.465  99.347  1.00 9.31  ? 480  ARG A NE  1 
ATOM   3608  C CZ  . ARG A 1 501 ? 96.889  96.138  99.358  1.00 9.31  ? 480  ARG A CZ  1 
ATOM   3609  N NH1 . ARG A 1 501 ? 97.602  95.445  98.486  1.00 9.31  ? 480  ARG A NH1 1 
ATOM   3610  N NH2 . ARG A 1 501 ? 96.139  95.501  100.246 1.00 9.31  ? 480  ARG A NH2 1 
ATOM   3611  N N   . GLU A 1 502 ? 99.814  99.777  94.680  1.00 8.31  ? 481  GLU A N   1 
ATOM   3612  C CA  . GLU A 1 502 ? 100.187 100.575 93.521  1.00 8.31  ? 481  GLU A CA  1 
ATOM   3613  C C   . GLU A 1 502 ? 99.664  101.997 93.672  1.00 8.31  ? 481  GLU A C   1 
ATOM   3614  O O   . GLU A 1 502 ? 98.851  102.296 94.549  1.00 8.31  ? 481  GLU A O   1 
ATOM   3615  C CB  . GLU A 1 502 ? 99.658  99.962  92.217  1.00 8.31  ? 481  GLU A CB  1 
ATOM   3616  C CG  . GLU A 1 502 ? 100.506 98.837  91.659  1.00 8.31  ? 481  GLU A CG  1 
ATOM   3617  C CD  . GLU A 1 502 ? 100.146 97.484  92.226  1.00 8.31  ? 481  GLU A CD  1 
ATOM   3618  O OE1 . GLU A 1 502 ? 101.020 96.837  92.838  1.00 8.31  ? 481  GLU A OE1 1 
ATOM   3619  O OE2 . GLU A 1 502 ? 98.986  97.065  92.055  1.00 8.31  ? 481  GLU A OE2 1 
ATOM   3620  N N   . THR A 1 503 ? 100.157 102.879 92.797  1.00 4.79  ? 482  THR A N   1 
ATOM   3621  C CA  . THR A 1 503 ? 99.749  104.284 92.701  1.00 4.79  ? 482  THR A CA  1 
ATOM   3622  C C   . THR A 1 503 ? 100.027 105.072 93.974  1.00 4.79  ? 482  THR A C   1 
ATOM   3623  O O   . THR A 1 503 ? 99.495  106.170 94.151  1.00 4.79  ? 482  THR A O   1 
ATOM   3624  C CB  . THR A 1 503 ? 98.268  104.431 92.323  1.00 4.79  ? 482  THR A CB  1 
ATOM   3625  O OG1 . THR A 1 503 ? 97.447  104.096 93.448  1.00 4.79  ? 482  THR A OG1 1 
ATOM   3626  C CG2 . THR A 1 503 ? 97.912  103.540 91.146  1.00 4.79  ? 482  THR A CG2 1 
ATOM   3627  N N   . HIS A 1 504 ? 100.851 104.543 94.870  1.00 3.78  ? 483  HIS A N   1 
ATOM   3628  C CA  . HIS A 1 504 ? 101.190 105.229 96.105  1.00 3.78  ? 483  HIS A CA  1 
ATOM   3629  C C   . HIS A 1 504 ? 102.701 105.336 96.219  1.00 3.78  ? 483  HIS A C   1 
ATOM   3630  O O   . HIS A 1 504 ? 103.450 104.666 95.507  1.00 3.78  ? 483  HIS A O   1 
ATOM   3631  C CB  . HIS A 1 504 ? 100.612 104.512 97.328  1.00 3.78  ? 483  HIS A CB  1 
ATOM   3632  C CG  . HIS A 1 504 ? 100.573 105.360 98.561  1.00 3.78  ? 483  HIS A CG  1 
ATOM   3633  N ND1 . HIS A 1 504 ? 101.451 105.188 99.608  1.00 3.78  ? 483  HIS A ND1 1 
ATOM   3634  C CD2 . HIS A 1 504 ? 99.766  106.386 98.913  1.00 3.78  ? 483  HIS A CD2 1 
ATOM   3635  C CE1 . HIS A 1 504 ? 101.185 106.070 100.553 1.00 3.78  ? 483  HIS A CE1 1 
ATOM   3636  N NE2 . HIS A 1 504 ? 100.166 106.810 100.156 1.00 3.78  ? 483  HIS A NE2 1 
ATOM   3637  N N   . LYS A 1 505 ? 103.144 106.198 97.131  1.00 2.99  ? 484  LYS A N   1 
ATOM   3638  C CA  . LYS A 1 505 ? 104.568 106.454 97.296  1.00 2.99  ? 484  LYS A CA  1 
ATOM   3639  C C   . LYS A 1 505 ? 105.323 105.236 97.809  1.00 2.99  ? 484  LYS A C   1 
ATOM   3640  O O   . LYS A 1 505 ? 106.551 105.201 97.705  1.00 2.99  ? 484  LYS A O   1 
ATOM   3641  C CB  . LYS A 1 505 ? 104.761 107.660 98.216  1.00 2.99  ? 484  LYS A CB  1 
ATOM   3642  C CG  . LYS A 1 505 ? 104.324 107.446 99.645  1.00 2.99  ? 484  LYS A CG  1 
ATOM   3643  C CD  . LYS A 1 505 ? 104.454 108.728 100.441 1.00 2.99  ? 484  LYS A CD  1 
ATOM   3644  C CE  . LYS A 1 505 ? 105.895 109.076 100.696 1.00 2.99  ? 484  LYS A CE  1 
ATOM   3645  N NZ  . LYS A 1 505 ? 106.018 110.274 101.557 1.00 2.99  ? 484  LYS A NZ  1 
ATOM   3646  N N   . MET A 1 506 ? 104.624 104.235 98.341  1.00 4.24  ? 485  MET A N   1 
ATOM   3647  C CA  . MET A 1 506 ? 105.256 102.994 98.762  1.00 4.24  ? 485  MET A CA  1 
ATOM   3648  C C   . MET A 1 506 ? 105.412 101.997 97.623  1.00 4.24  ? 485  MET A C   1 
ATOM   3649  O O   . MET A 1 506 ? 105.907 100.891 97.851  1.00 4.24  ? 485  MET A O   1 
ATOM   3650  C CB  . MET A 1 506 ? 104.477 102.359 99.921  1.00 4.24  ? 485  MET A CB  1 
ATOM   3651  C CG  . MET A 1 506 ? 102.987 102.197 99.688  1.00 4.24  ? 485  MET A CG  1 
ATOM   3652  S SD  . MET A 1 506 ? 102.228 101.080 100.883 1.00 4.24  ? 485  MET A SD  1 
ATOM   3653  C CE  . MET A 1 506 ? 100.517 101.602 100.818 1.00 4.24  ? 485  MET A CE  1 
ATOM   3654  N N   . MET A 1 507 ? 104.991 102.352 96.407  1.00 4.73  ? 486  MET A N   1 
ATOM   3655  C CA  . MET A 1 507 ? 105.515 101.670 95.228  1.00 4.73  ? 486  MET A CA  1 
ATOM   3656  C C   . MET A 1 507 ? 107.017 101.834 95.114  1.00 4.73  ? 486  MET A C   1 
ATOM   3657  O O   . MET A 1 507 ? 107.693 100.971 94.546  1.00 4.73  ? 486  MET A O   1 
ATOM   3658  C CB  . MET A 1 507 ? 104.860 102.198 93.957  1.00 4.73  ? 486  MET A CB  1 
ATOM   3659  C CG  . MET A 1 507 ? 103.545 101.588 93.612  1.00 4.73  ? 486  MET A CG  1 
ATOM   3660  S SD  . MET A 1 507 ? 103.836 99.939  92.944  1.00 4.73  ? 486  MET A SD  1 
ATOM   3661  C CE  . MET A 1 507 ? 103.678 100.253 91.189  1.00 4.73  ? 486  MET A CE  1 
ATOM   3662  N N   . LEU A 1 508 ? 107.553 102.946 95.618  1.00 2.36  ? 487  LEU A N   1 
ATOM   3663  C CA  . LEU A 1 508 ? 108.995 103.142 95.605  1.00 2.36  ? 487  LEU A CA  1 
ATOM   3664  C C   . LEU A 1 508 ? 109.691 102.058 96.410  1.00 2.36  ? 487  LEU A C   1 
ATOM   3665  O O   . LEU A 1 508 ? 110.719 101.522 95.985  1.00 2.36  ? 487  LEU A O   1 
ATOM   3666  C CB  . LEU A 1 508 ? 109.339 104.518 96.164  1.00 2.36  ? 487  LEU A CB  1 
ATOM   3667  C CG  . LEU A 1 508 ? 109.596 105.648 95.175  1.00 2.36  ? 487  LEU A CG  1 
ATOM   3668  C CD1 . LEU A 1 508 ? 109.977 106.893 95.940  1.00 2.36  ? 487  LEU A CD1 1 
ATOM   3669  C CD2 . LEU A 1 508 ? 110.680 105.271 94.197  1.00 2.36  ? 487  LEU A CD2 1 
ATOM   3670  N N   . ASP A 1 509 ? 109.138 101.717 97.573  1.00 3.24  ? 488  ASP A N   1 
ATOM   3671  C CA  . ASP A 1 509 ? 109.761 100.712 98.421  1.00 3.24  ? 488  ASP A CA  1 
ATOM   3672  C C   . ASP A 1 509 ? 109.671 99.327  97.807  1.00 3.24  ? 488  ASP A C   1 
ATOM   3673  O O   . ASP A 1 509 ? 110.540 98.485  98.053  1.00 3.24  ? 488  ASP A O   1 
ATOM   3674  C CB  . ASP A 1 509 ? 109.118 100.725 99.803  1.00 3.24  ? 488  ASP A CB  1 
ATOM   3675  C CG  . ASP A 1 509 ? 109.653 101.834 100.673 1.00 3.24  ? 488  ASP A CG  1 
ATOM   3676  O OD1 . ASP A 1 509 ? 110.841 102.183 100.518 1.00 3.24  ? 488  ASP A OD1 1 
ATOM   3677  O OD2 . ASP A 1 509 ? 108.889 102.359 101.508 1.00 3.24  ? 488  ASP A OD2 1 
ATOM   3678  N N   . HIS A 1 510 ? 108.636 99.068  97.013  1.00 4.13  ? 489  HIS A N   1 
ATOM   3679  C CA  . HIS A 1 510 ? 108.558 97.812  96.286  1.00 4.13  ? 489  HIS A CA  1 
ATOM   3680  C C   . HIS A 1 510 ? 109.613 97.704  95.200  1.00 4.13  ? 489  HIS A C   1 
ATOM   3681  O O   . HIS A 1 510 ? 109.778 96.626  94.633  1.00 4.13  ? 489  HIS A O   1 
ATOM   3682  C CB  . HIS A 1 510 ? 107.172 97.638  95.667  1.00 4.13  ? 489  HIS A CB  1 
ATOM   3683  C CG  . HIS A 1 510 ? 106.169 97.026  96.594  1.00 4.13  ? 489  HIS A CG  1 
ATOM   3684  N ND1 . HIS A 1 510 ? 105.190 97.763  97.222  1.00 4.13  ? 489  HIS A ND1 1 
ATOM   3685  C CD2 . HIS A 1 510 ? 105.994 95.746  96.997  1.00 4.13  ? 489  HIS A CD2 1 
ATOM   3686  C CE1 . HIS A 1 510 ? 104.455 96.964  97.974  1.00 4.13  ? 489  HIS A CE1 1 
ATOM   3687  N NE2 . HIS A 1 510 ? 104.922 95.735  97.856  1.00 4.13  ? 489  HIS A NE2 1 
ATOM   3688  N N   . TYR A 1 511 ? 110.308 98.791  94.878  1.00 2.16  ? 490  TYR A N   1 
ATOM   3689  C CA  . TYR A 1 511 ? 111.364 98.773  93.878  1.00 2.16  ? 490  TYR A CA  1 
ATOM   3690  C C   . TYR A 1 511 ? 112.710 99.174  94.456  1.00 2.16  ? 490  TYR A C   1 
ATOM   3691  O O   . TYR A 1 511 ? 113.636 99.482  93.702  1.00 2.16  ? 490  TYR A O   1 
ATOM   3692  C CB  . TYR A 1 511 ? 110.997 99.680  92.707  1.00 2.16  ? 490  TYR A CB  1 
ATOM   3693  C CG  . TYR A 1 511 ? 109.926 99.097  91.830  1.00 2.16  ? 490  TYR A CG  1 
ATOM   3694  C CD1 . TYR A 1 511 ? 110.245 98.207  90.823  1.00 2.16  ? 490  TYR A CD1 1 
ATOM   3695  C CD2 . TYR A 1 511 ? 108.593 99.421  92.019  1.00 2.16  ? 490  TYR A CD2 1 
ATOM   3696  C CE1 . TYR A 1 511 ? 109.277 97.668  90.025  1.00 2.16  ? 490  TYR A CE1 1 
ATOM   3697  C CE2 . TYR A 1 511 ? 107.615 98.881  91.224  1.00 2.16  ? 490  TYR A CE2 1 
ATOM   3698  C CZ  . TYR A 1 511 ? 107.963 98.006  90.228  1.00 2.16  ? 490  TYR A CZ  1 
ATOM   3699  O OH  . TYR A 1 511 ? 106.992 97.462  89.424  1.00 2.16  ? 490  TYR A OH  1 
ATOM   3700  N N   . GLN A 1 512 ? 112.839 99.171  95.772  1.00 1.62  ? 491  GLN A N   1 
ATOM   3701  C CA  . GLN A 1 512 ? 114.068 99.527  96.450  1.00 1.62  ? 491  GLN A CA  1 
ATOM   3702  C C   . GLN A 1 512 ? 114.359 98.484  97.514  1.00 1.62  ? 491  GLN A C   1 
ATOM   3703  O O   . GLN A 1 512 ? 113.457 97.812  98.016  1.00 1.62  ? 491  GLN A O   1 
ATOM   3704  C CB  . GLN A 1 512 ? 113.971 100.914 97.100  1.00 1.62  ? 491  GLN A CB  1 
ATOM   3705  C CG  . GLN A 1 512 ? 114.175 102.069 96.153  1.00 1.62  ? 491  GLN A CG  1 
ATOM   3706  C CD  . GLN A 1 512 ? 113.874 103.397 96.797  1.00 1.62  ? 491  GLN A CD  1 
ATOM   3707  O OE1 . GLN A 1 512 ? 114.393 104.427 96.384  1.00 1.62  ? 491  GLN A OE1 1 
ATOM   3708  N NE2 . GLN A 1 512 ? 113.034 103.382 97.816  1.00 1.62  ? 491  GLN A NE2 1 
ATOM   3709  N N   . GLN A 1 513 ? 115.631 98.356  97.857  1.00 2.79  ? 492  GLN A N   1 
ATOM   3710  C CA  . GLN A 1 513 ? 116.052 97.522  98.967  1.00 2.79  ? 492  GLN A CA  1 
ATOM   3711  C C   . GLN A 1 513 ? 116.697 98.405  100.022 1.00 2.79  ? 492  GLN A C   1 
ATOM   3712  O O   . GLN A 1 513 ? 117.220 99.478  99.724  1.00 2.79  ? 492  GLN A O   1 
ATOM   3713  C CB  . GLN A 1 513 ? 117.028 96.439  98.506  1.00 2.79  ? 492  GLN A CB  1 
ATOM   3714  C CG  . GLN A 1 513 ? 118.128 96.966  97.631  1.00 2.79  ? 492  GLN A CG  1 
ATOM   3715  C CD  . GLN A 1 513 ? 118.727 95.899  96.758  1.00 2.79  ? 492  GLN A CD  1 
ATOM   3716  O OE1 . GLN A 1 513 ? 118.315 94.745  96.805  1.00 2.79  ? 492  GLN A OE1 1 
ATOM   3717  N NE2 . GLN A 1 513 ? 119.714 96.273  95.957  1.00 2.79  ? 492  GLN A NE2 1 
ATOM   3718  N N   . THR A 1 514 ? 116.646 97.957  101.265 1.00 3.72  ? 493  THR A N   1 
ATOM   3719  C CA  . THR A 1 514 ? 117.258 98.688  102.361 1.00 3.72  ? 493  THR A CA  1 
ATOM   3720  C C   . THR A 1 514 ? 118.647 98.130  102.617 1.00 3.72  ? 493  THR A C   1 
ATOM   3721  O O   . THR A 1 514 ? 118.817 96.917  102.765 1.00 3.72  ? 493  THR A O   1 
ATOM   3722  C CB  . THR A 1 514 ? 116.410 98.602  103.630 1.00 3.72  ? 493  THR A CB  1 
ATOM   3723  O OG1 . THR A 1 514 ? 115.104 99.125  103.367 1.00 3.72  ? 493  THR A OG1 1 
ATOM   3724  C CG2 . THR A 1 514 ? 117.042 99.405  104.741 1.00 3.72  ? 493  THR A CG2 1 
ATOM   3725  N N   . LYS A 1 515 ? 119.632 99.012  102.657 1.00 2.57  ? 494  LYS A N   1 
ATOM   3726  C CA  . LYS A 1 515 ? 120.993 98.662  103.031 1.00 2.57  ? 494  LYS A CA  1 
ATOM   3727  C C   . LYS A 1 515 ? 121.220 99.169  104.443 1.00 2.57  ? 494  LYS A C   1 
ATOM   3728  O O   . LYS A 1 515 ? 121.175 100.376 104.687 1.00 2.57  ? 494  LYS A O   1 
ATOM   3729  C CB  . LYS A 1 515 ? 122.007 99.267  102.070 1.00 2.57  ? 494  LYS A CB  1 
ATOM   3730  C CG  . LYS A 1 515 ? 123.408 99.267  102.616 1.00 2.57  ? 494  LYS A CG  1 
ATOM   3731  C CD  . LYS A 1 515 ? 124.415 99.416  101.512 1.00 2.57  ? 494  LYS A CD  1 
ATOM   3732  C CE  . LYS A 1 515 ? 124.769 98.083  100.928 1.00 2.57  ? 494  LYS A CE  1 
ATOM   3733  N NZ  . LYS A 1 515 ? 125.280 97.187  101.977 1.00 2.57  ? 494  LYS A NZ  1 
ATOM   3734  N N   . ASN A 1 516 ? 121.445 98.253  105.372 1.00 3.50  ? 495  ASN A N   1 
ATOM   3735  C CA  . ASN A 1 516 ? 121.780 98.617  106.734 1.00 3.50  ? 495  ASN A CA  1 
ATOM   3736  C C   . ASN A 1 516 ? 123.293 98.666  106.874 1.00 3.50  ? 495  ASN A C   1 
ATOM   3737  O O   . ASN A 1 516 ? 123.988 97.714  106.510 1.00 3.50  ? 495  ASN A O   1 
ATOM   3738  C CB  . ASN A 1 516 ? 121.183 97.620  107.721 1.00 3.50  ? 495  ASN A CB  1 
ATOM   3739  C CG  . ASN A 1 516 ? 121.319 98.071  109.152 1.00 3.50  ? 495  ASN A CG  1 
ATOM   3740  O OD1 . ASN A 1 516 ? 120.710 99.052  109.563 1.00 3.50  ? 495  ASN A OD1 1 
ATOM   3741  N ND2 . ASN A 1 516 ? 122.125 97.361  109.920 1.00 3.50  ? 495  ASN A ND2 1 
ATOM   3742  N N   . MET A 1 517 ? 123.800 99.786  107.371 1.00 2.21  ? 496  MET A N   1 
ATOM   3743  C CA  . MET A 1 517 ? 125.210 99.943  107.703 1.00 2.21  ? 496  MET A CA  1 
ATOM   3744  C C   . MET A 1 517 ? 125.287 100.222 109.193 1.00 2.21  ? 496  MET A C   1 
ATOM   3745  O O   . MET A 1 517 ? 124.938 101.316 109.637 1.00 2.21  ? 496  MET A O   1 
ATOM   3746  C CB  . MET A 1 517 ? 125.854 101.067 106.898 1.00 2.21  ? 496  MET A CB  1 
ATOM   3747  C CG  . MET A 1 517 ? 126.423 100.619 105.573 1.00 2.21  ? 496  MET A CG  1 
ATOM   3748  S SD  . MET A 1 517 ? 126.763 101.991 104.465 1.00 2.21  ? 496  MET A SD  1 
ATOM   3749  C CE  . MET A 1 517 ? 128.109 102.800 105.321 1.00 2.21  ? 496  MET A CE  1 
ATOM   3750  N N   . LEU A 1 518 ? 125.700 99.229  109.965 1.00 2.46  ? 497  LEU A N   1 
ATOM   3751  C CA  . LEU A 1 518 ? 125.856 99.391  111.404 1.00 2.46  ? 497  LEU A CA  1 
ATOM   3752  C C   . LEU A 1 518 ? 127.296 99.806  111.665 1.00 2.46  ? 497  LEU A C   1 
ATOM   3753  O O   . LEU A 1 518 ? 128.228 99.037  111.415 1.00 2.46  ? 497  LEU A O   1 
ATOM   3754  C CB  . LEU A 1 518 ? 125.491 98.101  112.130 1.00 2.46  ? 497  LEU A CB  1 
ATOM   3755  C CG  . LEU A 1 518 ? 125.185 98.170  113.623 1.00 2.46  ? 497  LEU A CG  1 
ATOM   3756  C CD1 . LEU A 1 518 ? 124.286 99.332  113.933 1.00 2.46  ? 497  LEU A CD1 1 
ATOM   3757  C CD2 . LEU A 1 518 ? 124.521 96.893  114.053 1.00 2.46  ? 497  LEU A CD2 1 
ATOM   3758  N N   . VAL A 1 519 ? 127.480 101.031 112.145 1.00 2.47  ? 498  VAL A N   1 
ATOM   3759  C CA  . VAL A 1 519 ? 128.794 101.625 112.341 1.00 2.47  ? 498  VAL A CA  1 
ATOM   3760  C C   . VAL A 1 519 ? 129.013 101.808 113.831 1.00 2.47  ? 498  VAL A C   1 
ATOM   3761  O O   . VAL A 1 519 ? 128.146 102.343 114.532 1.00 2.47  ? 498  VAL A O   1 
ATOM   3762  C CB  . VAL A 1 519 ? 128.923 102.966 111.604 1.00 2.47  ? 498  VAL A CB  1 
ATOM   3763  C CG1 . VAL A 1 519 ? 130.357 103.443 111.639 1.00 2.47  ? 498  VAL A CG1 1 
ATOM   3764  C CG2 . VAL A 1 519 ? 128.437 102.837 110.181 1.00 2.47  ? 498  VAL A CG2 1 
ATOM   3765  N N   . SER A 1 520 ? 130.163 101.354 114.314 1.00 3.92  ? 499  SER A N   1 
ATOM   3766  C CA  . SER A 1 520 ? 130.574 101.548 115.694 1.00 3.92  ? 499  SER A CA  1 
ATOM   3767  C C   . SER A 1 520 ? 131.674 102.593 115.734 1.00 3.92  ? 499  SER A C   1 
ATOM   3768  O O   . SER A 1 520 ? 132.667 102.480 115.010 1.00 3.92  ? 499  SER A O   1 
ATOM   3769  C CB  . SER A 1 520 ? 131.073 100.245 116.311 1.00 3.92  ? 499  SER A CB  1 
ATOM   3770  O OG  . SER A 1 520 ? 131.082 100.320 117.722 1.00 3.92  ? 499  SER A OG  1 
ATOM   3771  N N   . TYR A 1 521 ? 131.491 103.611 116.571 1.00 3.32  ? 500  TYR A N   1 
ATOM   3772  C CA  . TYR A 1 521 ? 132.493 104.647 116.765 1.00 3.32  ? 500  TYR A CA  1 
ATOM   3773  C C   . TYR A 1 521 ? 133.206 104.500 118.101 1.00 3.32  ? 500  TYR A C   1 
ATOM   3774  O O   . TYR A 1 521 ? 133.792 105.463 118.601 1.00 3.32  ? 500  TYR A O   1 
ATOM   3775  C CB  . TYR A 1 521 ? 131.856 106.028 116.647 1.00 3.32  ? 500  TYR A CB  1 
ATOM   3776  C CG  . TYR A 1 521 ? 131.110 106.255 115.356 1.00 3.32  ? 500  TYR A CG  1 
ATOM   3777  C CD1 . TYR A 1 521 ? 131.780 106.608 114.201 1.00 3.32  ? 500  TYR A CD1 1 
ATOM   3778  C CD2 . TYR A 1 521 ? 129.731 106.133 115.300 1.00 3.32  ? 500  TYR A CD2 1 
ATOM   3779  C CE1 . TYR A 1 521 ? 131.101 106.821 113.026 1.00 3.32  ? 500  TYR A CE1 1 
ATOM   3780  C CE2 . TYR A 1 521 ? 129.047 106.340 114.130 1.00 3.32  ? 500  TYR A CE2 1 
ATOM   3781  C CZ  . TYR A 1 521 ? 129.735 106.688 112.998 1.00 3.32  ? 500  TYR A CZ  1 
ATOM   3782  O OH  . TYR A 1 521 ? 129.054 106.904 111.826 1.00 3.32  ? 500  TYR A OH  1 
ATOM   3783  N N   . SER A 1 522 ? 133.150 103.313 118.697 1.00 8.42  ? 501  SER A N   1 
ATOM   3784  C CA  . SER A 1 522 ? 133.850 103.013 119.934 1.00 8.42  ? 501  SER A CA  1 
ATOM   3785  C C   . SER A 1 522 ? 134.993 102.061 119.638 1.00 8.42  ? 501  SER A C   1 
ATOM   3786  O O   . SER A 1 522 ? 134.750 100.967 119.110 1.00 8.42  ? 501  SER A O   1 
ATOM   3787  C CB  . SER A 1 522 ? 132.901 102.396 120.955 1.00 8.42  ? 501  SER A CB  1 
ATOM   3788  O OG  . SER A 1 522 ? 133.587 102.051 122.143 1.00 8.42  ? 501  SER A OG  1 
ATOM   3789  N N   . PRO A 1 523 ? 136.234 102.416 119.944 1.00 10.07 ? 502  PRO A N   1 
ATOM   3790  C CA  . PRO A 1 523 ? 137.341 101.481 119.715 1.00 10.07 ? 502  PRO A CA  1 
ATOM   3791  C C   . PRO A 1 523 ? 137.541 100.515 120.872 1.00 10.07 ? 502  PRO A C   1 
ATOM   3792  O O   . PRO A 1 523 ? 138.599 99.895  120.993 1.00 10.07 ? 502  PRO A O   1 
ATOM   3793  C CB  . PRO A 1 523 ? 138.543 102.412 119.543 1.00 10.07 ? 502  PRO A CB  1 
ATOM   3794  C CG  . PRO A 1 523 ? 138.205 103.597 120.383 1.00 10.07 ? 502  PRO A CG  1 
ATOM   3795  C CD  . PRO A 1 523 ? 136.704 103.736 120.396 1.00 10.07 ? 502  PRO A CD  1 
ATOM   3796  N N   . LYS A 1 524 ? 136.533 100.376 121.724 1.00 13.11 ? 503  LYS A N   1 
ATOM   3797  C CA  . LYS A 1 524 ? 136.596 99.511  122.894 1.00 13.11 ? 503  LYS A CA  1 
ATOM   3798  C C   . LYS A 1 524 ? 136.026 98.141  122.555 1.00 13.11 ? 503  LYS A C   1 
ATOM   3799  O O   . LYS A 1 524 ? 134.941 98.043  121.972 1.00 13.11 ? 503  LYS A O   1 
ATOM   3800  C CB  . LYS A 1 524 ? 135.822 100.129 124.060 1.00 13.11 ? 503  LYS A CB  1 
ATOM   3801  C CG  . LYS A 1 524 ? 136.256 101.541 124.461 1.00 13.11 ? 503  LYS A CG  1 
ATOM   3802  C CD  . LYS A 1 524 ? 137.766 101.717 124.630 1.00 13.11 ? 503  LYS A CD  1 
ATOM   3803  C CE  . LYS A 1 524 ? 138.380 100.629 125.514 1.00 13.11 ? 503  LYS A CE  1 
ATOM   3804  N NZ  . LYS A 1 524 ? 139.855 100.529 125.371 1.00 13.11 ? 503  LYS A NZ  1 
ATOM   3805  N N   . LYS A 1 525 ? 136.750 97.090  122.935 1.00 15.99 ? 504  LYS A N   1 
ATOM   3806  C CA  . LYS A 1 525 ? 136.321 95.734  122.629 1.00 15.99 ? 504  LYS A CA  1 
ATOM   3807  C C   . LYS A 1 525 ? 135.004 95.413  123.325 1.00 15.99 ? 504  LYS A C   1 
ATOM   3808  O O   . LYS A 1 525 ? 134.667 95.981  124.366 1.00 15.99 ? 504  LYS A O   1 
ATOM   3809  C CB  . LYS A 1 525 ? 137.392 94.727  123.046 1.00 15.99 ? 504  LYS A CB  1 
ATOM   3810  C CG  . LYS A 1 525 ? 137.480 94.505  124.547 1.00 15.99 ? 504  LYS A CG  1 
ATOM   3811  C CD  . LYS A 1 525 ? 138.840 93.966  124.960 1.00 15.99 ? 504  LYS A CD  1 
ATOM   3812  C CE  . LYS A 1 525 ? 139.251 92.784  124.105 1.00 15.99 ? 504  LYS A CE  1 
ATOM   3813  N NZ  . LYS A 1 525 ? 140.420 92.058  124.679 1.00 15.99 ? 504  LYS A NZ  1 
ATOM   3814  N N   . LEU A 1 526 ? 134.249 94.493  122.720 1.00 20.69 ? 505  LEU A N   1 
ATOM   3815  C CA  . LEU A 1 526 ? 132.936 94.130  123.244 1.00 20.69 ? 505  LEU A CA  1 
ATOM   3816  C C   . LEU A 1 526 ? 133.043 93.539  124.644 1.00 20.69 ? 505  LEU A C   1 
ATOM   3817  O O   . LEU A 1 526 ? 132.256 93.875  125.536 1.00 20.69 ? 505  LEU A O   1 
ATOM   3818  C CB  . LEU A 1 526 ? 132.258 93.144  122.294 1.00 20.69 ? 505  LEU A CB  1 
ATOM   3819  C CG  . LEU A 1 526 ? 131.829 93.691  120.933 1.00 20.69 ? 505  LEU A CG  1 
ATOM   3820  C CD1 . LEU A 1 526 ? 131.355 92.565  120.028 1.00 20.69 ? 505  LEU A CD1 1 
ATOM   3821  C CD2 . LEU A 1 526 ? 130.743 94.746  121.095 1.00 20.69 ? 505  LEU A CD2 1 
ATOM   3822  N N   . GLY A 1 527 ? 134.012 92.654  124.854 1.00 20.69 ? 506  GLY A N   1 
ATOM   3823  C CA  . GLY A 1 527 ? 134.178 92.004  126.137 1.00 20.69 ? 506  GLY A CA  1 
ATOM   3824  C C   . GLY A 1 527 ? 134.007 90.502  126.062 1.00 20.69 ? 506  GLY A C   1 
ATOM   3825  O O   . GLY A 1 527 ? 134.770 89.755  126.681 1.00 20.69 ? 506  GLY A O   1 
ATOM   3826  N N   . PHE A 1 528 ? 133.012 90.045  125.308 1.00 24.07 ? 507  PHE A N   1 
ATOM   3827  C CA  . PHE A 1 528 ? 132.825 88.622  125.051 1.00 24.07 ? 507  PHE A CA  1 
ATOM   3828  C C   . PHE A 1 528 ? 133.610 88.249  123.800 1.00 24.07 ? 507  PHE A C   1 
ATOM   3829  O O   . PHE A 1 528 ? 133.445 88.879  122.749 1.00 24.07 ? 507  PHE A O   1 
ATOM   3830  C CB  . PHE A 1 528 ? 131.342 88.270  124.909 1.00 24.07 ? 507  PHE A CB  1 
ATOM   3831  C CG  . PHE A 1 528 ? 130.622 89.032  123.831 1.00 24.07 ? 507  PHE A CG  1 
ATOM   3832  C CD1 . PHE A 1 528 ? 130.188 90.330  124.048 1.00 24.07 ? 507  PHE A CD1 1 
ATOM   3833  C CD2 . PHE A 1 528 ? 130.352 88.437  122.610 1.00 24.07 ? 507  PHE A CD2 1 
ATOM   3834  C CE1 . PHE A 1 528 ? 129.513 91.026  123.062 1.00 24.07 ? 507  PHE A CE1 1 
ATOM   3835  C CE2 . PHE A 1 528 ? 129.680 89.127  121.617 1.00 24.07 ? 507  PHE A CE2 1 
ATOM   3836  C CZ  . PHE A 1 528 ? 129.259 90.422  121.843 1.00 24.07 ? 507  PHE A CZ  1 
ATOM   3837  N N   . PHE A 1 529 ? 134.465 87.236  123.923 1.00 19.80 ? 508  PHE A N   1 
ATOM   3838  C CA  . PHE A 1 529 ? 135.516 86.937  122.948 1.00 19.80 ? 508  PHE A CA  1 
ATOM   3839  C C   . PHE A 1 529 ? 136.512 88.088  122.904 1.00 19.80 ? 508  PHE A C   1 
ATOM   3840  O O   . PHE A 1 529 ? 136.681 88.811  123.884 1.00 19.80 ? 508  PHE A O   1 
ATOM   3841  C CB  . PHE A 1 529 ? 134.949 86.673  121.547 1.00 19.80 ? 508  PHE A CB  1 
ATOM   3842  C CG  . PHE A 1 529 ? 134.296 85.335  121.398 1.00 19.80 ? 508  PHE A CG  1 
ATOM   3843  C CD1 . PHE A 1 529 ? 134.664 84.276  122.206 1.00 19.80 ? 508  PHE A CD1 1 
ATOM   3844  C CD2 . PHE A 1 529 ? 133.316 85.134  120.446 1.00 19.80 ? 508  PHE A CD2 1 
ATOM   3845  C CE1 . PHE A 1 529 ? 134.066 83.045  122.066 1.00 19.80 ? 508  PHE A CE1 1 
ATOM   3846  C CE2 . PHE A 1 529 ? 132.713 83.903  120.307 1.00 19.80 ? 508  PHE A CE2 1 
ATOM   3847  C CZ  . PHE A 1 529 ? 133.088 82.859  121.118 1.00 19.80 ? 508  PHE A CZ  1 
ATOM   3848  N N   . GLY B 1 32  ? 118.598 76.446  139.193 1.00 20.16 ? 11   GLY B N   1 
ATOM   3849  C CA  . GLY B 1 32  ? 119.596 75.434  138.904 1.00 20.16 ? 11   GLY B CA  1 
ATOM   3850  C C   . GLY B 1 32  ? 119.819 75.227  137.421 1.00 20.16 ? 11   GLY B C   1 
ATOM   3851  O O   . GLY B 1 32  ? 118.990 74.629  136.741 1.00 20.16 ? 11   GLY B O   1 
ATOM   3852  N N   . VAL B 1 33  ? 120.947 75.732  136.918 1.00 20.39 ? 12   VAL B N   1 
ATOM   3853  C CA  . VAL B 1 33  ? 121.265 75.578  135.503 1.00 20.39 ? 12   VAL B CA  1 
ATOM   3854  C C   . VAL B 1 33  ? 121.575 74.122  135.182 1.00 20.39 ? 12   VAL B C   1 
ATOM   3855  O O   . VAL B 1 33  ? 121.186 73.607  134.127 1.00 20.39 ? 12   VAL B O   1 
ATOM   3856  C CB  . VAL B 1 33  ? 122.426 76.511  135.115 1.00 20.39 ? 12   VAL B CB  1 
ATOM   3857  C CG1 . VAL B 1 33  ? 123.013 76.111  133.773 1.00 20.39 ? 12   VAL B CG1 1 
ATOM   3858  C CG2 . VAL B 1 33  ? 121.957 77.952  135.085 1.00 20.39 ? 12   VAL B CG2 1 
ATOM   3859  N N   . ASN B 1 34  ? 122.264 73.432  136.085 1.00 24.60 ? 13   ASN B N   1 
ATOM   3860  C CA  . ASN B 1 34  ? 122.597 72.028  135.883 1.00 24.60 ? 13   ASN B CA  1 
ATOM   3861  C C   . ASN B 1 34  ? 121.441 71.091  136.210 1.00 24.60 ? 13   ASN B C   1 
ATOM   3862  O O   . ASN B 1 34  ? 121.593 69.874  136.060 1.00 24.60 ? 13   ASN B O   1 
ATOM   3863  C CB  . ASN B 1 34  ? 123.823 71.656  136.721 1.00 24.60 ? 13   ASN B CB  1 
ATOM   3864  C CG  . ASN B 1 34  ? 125.127 71.902  135.986 1.00 24.60 ? 13   ASN B CG  1 
ATOM   3865  O OD1 . ASN B 1 34  ? 125.317 71.438  134.862 1.00 24.60 ? 13   ASN B OD1 1 
ATOM   3866  N ND2 . ASN B 1 34  ? 126.032 72.637  136.619 1.00 24.60 ? 13   ASN B ND2 1 
ATOM   3867  N N   . ALA B 1 35  ? 120.305 71.623  136.654 1.00 22.15 ? 14   ALA B N   1 
ATOM   3868  C CA  . ALA B 1 35  ? 119.112 70.832  136.913 1.00 22.15 ? 14   ALA B CA  1 
ATOM   3869  C C   . ALA B 1 35  ? 118.211 70.821  135.684 1.00 22.15 ? 14   ALA B C   1 
ATOM   3870  O O   . ALA B 1 35  ? 118.168 71.785  134.915 1.00 22.15 ? 14   ALA B O   1 
ATOM   3871  C CB  . ALA B 1 35  ? 118.347 71.383  138.116 1.00 22.15 ? 14   ALA B CB  1 
ATOM   3872  N N   . LEU B 1 36  ? 117.490 69.719  135.507 1.00 22.09 ? 15   LEU B N   1 
ATOM   3873  C CA  . LEU B 1 36  ? 116.704 69.535  134.292 1.00 22.09 ? 15   LEU B CA  1 
ATOM   3874  C C   . LEU B 1 36  ? 115.532 70.509  134.263 1.00 22.09 ? 15   LEU B C   1 
ATOM   3875  O O   . LEU B 1 36  ? 114.764 70.576  135.228 1.00 22.09 ? 15   LEU B O   1 
ATOM   3876  C CB  . LEU B 1 36  ? 116.193 68.103  134.191 1.00 22.09 ? 15   LEU B CB  1 
ATOM   3877  C CG  . LEU B 1 36  ? 115.962 67.625  132.758 1.00 22.09 ? 15   LEU B CG  1 
ATOM   3878  C CD1 . LEU B 1 36  ? 117.295 67.403  132.066 1.00 22.09 ? 15   LEU B CD1 1 
ATOM   3879  C CD2 . LEU B 1 36  ? 115.122 66.363  132.731 1.00 22.09 ? 15   LEU B CD2 1 
ATOM   3880  N N   . PRO B 1 37  ? 115.365 71.278  133.188 1.00 21.13 ? 16   PRO B N   1 
ATOM   3881  C CA  . PRO B 1 37  ? 114.253 72.238  133.094 1.00 21.13 ? 16   PRO B CA  1 
ATOM   3882  C C   . PRO B 1 37  ? 113.028 71.749  132.332 1.00 21.13 ? 16   PRO B C   1 
ATOM   3883  O O   . PRO B 1 37  ? 112.087 72.534  132.171 1.00 21.13 ? 16   PRO B O   1 
ATOM   3884  C CB  . PRO B 1 37  ? 114.912 73.398  132.342 1.00 21.13 ? 16   PRO B CB  1 
ATOM   3885  C CG  . PRO B 1 37  ? 115.906 72.721  131.425 1.00 21.13 ? 16   PRO B CG  1 
ATOM   3886  C CD  . PRO B 1 37  ? 116.276 71.389  132.037 1.00 21.13 ? 16   PRO B CD  1 
ATOM   3887  N N   . PHE B 1 38  ? 113.007 70.502  131.872 1.00 20.84 ? 17   PHE B N   1 
ATOM   3888  C CA  . PHE B 1 38  ? 112.005 70.027  130.930 1.00 20.84 ? 17   PHE B CA  1 
ATOM   3889  C C   . PHE B 1 38  ? 111.141 68.946  131.559 1.00 20.84 ? 17   PHE B C   1 
ATOM   3890  O O   . PHE B 1 38  ? 111.660 68.002  132.163 1.00 20.84 ? 17   PHE B O   1 
ATOM   3891  C CB  . PHE B 1 38  ? 112.664 69.472  129.668 1.00 20.84 ? 17   PHE B CB  1 
ATOM   3892  C CG  . PHE B 1 38  ? 113.450 70.485  128.905 1.00 20.84 ? 17   PHE B CG  1 
ATOM   3893  C CD1 . PHE B 1 38  ? 112.986 71.777  128.766 1.00 20.84 ? 17   PHE B CD1 1 
ATOM   3894  C CD2 . PHE B 1 38  ? 114.657 70.146  128.327 1.00 20.84 ? 17   PHE B CD2 1 
ATOM   3895  C CE1 . PHE B 1 38  ? 113.707 72.709  128.061 1.00 20.84 ? 17   PHE B CE1 1 
ATOM   3896  C CE2 . PHE B 1 38  ? 115.382 71.076  127.619 1.00 20.84 ? 17   PHE B CE2 1 
ATOM   3897  C CZ  . PHE B 1 38  ? 114.907 72.359  127.486 1.00 20.84 ? 17   PHE B CZ  1 
ATOM   3898  N N   . GLU B 1 39  ? 109.829 69.085  131.406 1.00 25.36 ? 18   GLU B N   1 
ATOM   3899  C CA  . GLU B 1 39  ? 108.936 67.963  131.631 1.00 25.36 ? 18   GLU B CA  1 
ATOM   3900  C C   . GLU B 1 39  ? 109.118 66.934  130.523 1.00 25.36 ? 18   GLU B C   1 
ATOM   3901  O O   . GLU B 1 39  ? 109.555 67.253  129.414 1.00 25.36 ? 18   GLU B O   1 
ATOM   3902  C CB  . GLU B 1 39  ? 107.484 68.434  131.684 1.00 25.36 ? 18   GLU B CB  1 
ATOM   3903  C CG  . GLU B 1 39  ? 107.073 69.061  133.003 1.00 25.36 ? 18   GLU B CG  1 
ATOM   3904  C CD  . GLU B 1 39  ? 107.401 70.537  133.084 1.00 25.36 ? 18   GLU B CD  1 
ATOM   3905  O OE1 . GLU B 1 39  ? 108.556 70.910  132.796 1.00 25.36 ? 18   GLU B OE1 1 
ATOM   3906  O OE2 . GLU B 1 39  ? 106.500 71.328  133.433 1.00 25.36 ? 18   GLU B OE2 1 
ATOM   3907  N N   . GLU B 1 40  ? 108.785 65.687  130.832 1.00 28.70 ? 19   GLU B N   1 
ATOM   3908  C CA  . GLU B 1 40  ? 108.973 64.587  129.898 1.00 28.70 ? 19   GLU B CA  1 
ATOM   3909  C C   . GLU B 1 40  ? 107.812 64.425  128.930 1.00 28.70 ? 19   GLU B C   1 
ATOM   3910  O O   . GLU B 1 40  ? 107.850 63.526  128.088 1.00 28.70 ? 19   GLU B O   1 
ATOM   3911  C CB  . GLU B 1 40  ? 109.189 63.279  130.659 1.00 28.70 ? 19   GLU B CB  1 
ATOM   3912  C CG  . GLU B 1 40  ? 108.125 62.988  131.699 1.00 28.70 ? 19   GLU B CG  1 
ATOM   3913  C CD  . GLU B 1 40  ? 108.459 63.576  133.051 1.00 28.70 ? 19   GLU B CD  1 
ATOM   3914  O OE1 . GLU B 1 40  ? 108.485 62.815  134.040 1.00 28.70 ? 19   GLU B OE1 1 
ATOM   3915  O OE2 . GLU B 1 40  ? 108.694 64.800  133.126 1.00 28.70 ? 19   GLU B OE2 1 
ATOM   3916  N N   . ARG B 1 41  ? 106.785 65.266  129.029 1.00 23.58 ? 20   ARG B N   1 
ATOM   3917  C CA  . ARG B 1 41  ? 105.613 65.183  128.161 1.00 23.58 ? 20   ARG B CA  1 
ATOM   3918  C C   . ARG B 1 41  ? 105.248 66.595  127.720 1.00 23.58 ? 20   ARG B C   1 
ATOM   3919  O O   . ARG B 1 41  ? 104.495 67.293  128.404 1.00 23.58 ? 20   ARG B O   1 
ATOM   3920  C CB  . ARG B 1 41  ? 104.456 64.498  128.875 1.00 23.58 ? 20   ARG B CB  1 
ATOM   3921  C CG  . ARG B 1 41  ? 103.396 63.933  127.945 1.00 23.58 ? 20   ARG B CG  1 
ATOM   3922  C CD  . ARG B 1 41  ? 103.963 62.835  127.062 1.00 23.58 ? 20   ARG B CD  1 
ATOM   3923  N NE  . ARG B 1 41  ? 102.958 61.834  126.722 1.00 23.58 ? 20   ARG B NE  1 
ATOM   3924  C CZ  . ARG B 1 41  ? 103.241 60.606  126.302 1.00 23.58 ? 20   ARG B CZ  1 
ATOM   3925  N NH1 . ARG B 1 41  ? 104.503 60.223  126.169 1.00 23.58 ? 20   ARG B NH1 1 
ATOM   3926  N NH2 . ARG B 1 41  ? 102.262 59.758  126.018 1.00 23.58 ? 20   ARG B NH2 1 
ATOM   3927  N N   . TYR B 1 42  ? 105.791 67.015  126.580 1.00 19.60 ? 21   TYR B N   1 
ATOM   3928  C CA  . TYR B 1 42  ? 105.386 68.252  125.915 1.00 19.60 ? 21   TYR B CA  1 
ATOM   3929  C C   . TYR B 1 42  ? 104.417 67.914  124.792 1.00 19.60 ? 21   TYR B C   1 
ATOM   3930  O O   . TYR B 1 42  ? 104.814 67.427  123.731 1.00 19.60 ? 21   TYR B O   1 
ATOM   3931  C CB  . TYR B 1 42  ? 106.597 69.032  125.413 1.00 19.60 ? 21   TYR B CB  1 
ATOM   3932  C CG  . TYR B 1 42  ? 107.348 69.748  126.511 1.00 19.60 ? 21   TYR B CG  1 
ATOM   3933  C CD1 . TYR B 1 42  ? 106.750 69.984  127.738 1.00 19.60 ? 21   TYR B CD1 1 
ATOM   3934  C CD2 . TYR B 1 42  ? 108.651 70.180  126.327 1.00 19.60 ? 21   TYR B CD2 1 
ATOM   3935  C CE1 . TYR B 1 42  ? 107.417 70.643  128.746 1.00 19.60 ? 21   TYR B CE1 1 
ATOM   3936  C CE2 . TYR B 1 42  ? 109.330 70.839  127.334 1.00 19.60 ? 21   TYR B CE2 1 
ATOM   3937  C CZ  . TYR B 1 42  ? 108.704 71.066  128.543 1.00 19.60 ? 21   TYR B CZ  1 
ATOM   3938  O OH  . TYR B 1 42  ? 109.366 71.718  129.555 1.00 19.60 ? 21   TYR B OH  1 
ATOM   3939  N N   . ASP B 1 43  ? 103.139 68.178  125.038 1.00 16.97 ? 22   ASP B N   1 
ATOM   3940  C CA  . ASP B 1 43  ? 102.097 68.017  124.038 1.00 16.97 ? 22   ASP B CA  1 
ATOM   3941  C C   . ASP B 1 43  ? 102.111 69.229  123.111 1.00 16.97 ? 22   ASP B C   1 
ATOM   3942  O O   . ASP B 1 43  ? 103.039 70.041  123.120 1.00 16.97 ? 22   ASP B O   1 
ATOM   3943  C CB  . ASP B 1 43  ? 100.743 67.836  124.715 1.00 16.97 ? 22   ASP B CB  1 
ATOM   3944  C CG  . ASP B 1 43  ? 100.540 66.436  125.252 1.00 16.97 ? 22   ASP B CG  1 
ATOM   3945  O OD1 . ASP B 1 43  ? 101.211 65.503  124.763 1.00 16.97 ? 22   ASP B OD1 1 
ATOM   3946  O OD2 . ASP B 1 43  ? 99.708  66.273  126.169 1.00 16.97 ? 22   ASP B OD2 1 
ATOM   3947  N N   . ASN B 1 44  ? 101.077 69.365  122.293 1.00 11.56 ? 23   ASN B N   1 
ATOM   3948  C CA  . ASN B 1 44  ? 100.955 70.484  121.373 1.00 11.56 ? 23   ASN B CA  1 
ATOM   3949  C C   . ASN B 1 44  ? 100.116 71.572  122.028 1.00 11.56 ? 23   ASN B C   1 
ATOM   3950  O O   . ASN B 1 44  ? 98.957  71.339  122.380 1.00 11.56 ? 23   ASN B O   1 
ATOM   3951  C CB  . ASN B 1 44  ? 100.325 70.038  120.056 1.00 11.56 ? 23   ASN B CB  1 
ATOM   3952  C CG  . ASN B 1 44  ? 101.324 69.398  119.124 1.00 11.56 ? 23   ASN B CG  1 
ATOM   3953  O OD1 . ASN B 1 44  ? 102.517 69.685  119.183 1.00 11.56 ? 23   ASN B OD1 1 
ATOM   3954  N ND2 . ASN B 1 44  ? 100.843 68.524  118.253 1.00 11.56 ? 23   ASN B ND2 1 
ATOM   3955  N N   . PHE B 1 45  ? 100.702 72.749  122.197 1.00 8.65  ? 24   PHE B N   1 
ATOM   3956  C CA  . PHE B 1 45  ? 99.960  73.893  122.701 1.00 8.65  ? 24   PHE B CA  1 
ATOM   3957  C C   . PHE B 1 45  ? 99.025  74.393  121.610 1.00 8.65  ? 24   PHE B C   1 
ATOM   3958  O O   . PHE B 1 45  ? 99.481  74.862  120.563 1.00 8.65  ? 24   PHE B O   1 
ATOM   3959  C CB  . PHE B 1 45  ? 100.926 74.991  123.133 1.00 8.65  ? 24   PHE B CB  1 
ATOM   3960  C CG  . PHE B 1 45  ? 100.306 76.050  123.994 1.00 8.65  ? 24   PHE B CG  1 
ATOM   3961  C CD1 . PHE B 1 45  ? 100.286 75.919  125.366 1.00 8.65  ? 24   PHE B CD1 1 
ATOM   3962  C CD2 . PHE B 1 45  ? 99.769  77.188  123.432 1.00 8.65  ? 24   PHE B CD2 1 
ATOM   3963  C CE1 . PHE B 1 45  ? 99.730  76.891  126.154 1.00 8.65  ? 24   PHE B CE1 1 
ATOM   3964  C CE2 . PHE B 1 45  ? 99.215  78.165  124.217 1.00 8.65  ? 24   PHE B CE2 1 
ATOM   3965  C CZ  . PHE B 1 45  ? 99.194  78.016  125.579 1.00 8.65  ? 24   PHE B CZ  1 
ATOM   3966  N N   . ILE B 1 46  ? 97.721  74.285  121.847 1.00 9.15  ? 25   ILE B N   1 
ATOM   3967  C CA  . ILE B 1 46  ? 96.723  74.655  120.851 1.00 9.15  ? 25   ILE B CA  1 
ATOM   3968  C C   . ILE B 1 46  ? 95.505  75.225  121.560 1.00 9.15  ? 25   ILE B C   1 
ATOM   3969  O O   . ILE B 1 46  ? 94.912  74.566  122.419 1.00 9.15  ? 25   ILE B O   1 
ATOM   3970  C CB  . ILE B 1 46  ? 96.333  73.452  119.975 1.00 9.15  ? 25   ILE B CB  1 
ATOM   3971  C CG1 . ILE B 1 46  ? 97.359  73.229  118.872 1.00 9.15  ? 25   ILE B CG1 1 
ATOM   3972  C CG2 . ILE B 1 46  ? 94.974  73.665  119.361 1.00 9.15  ? 25   ILE B CG2 1 
ATOM   3973  C CD1 . ILE B 1 46  ? 97.211  71.906  118.173 1.00 9.15  ? 25   ILE B CD1 1 
ATOM   3974  N N   . GLY B 1 47  ? 95.127  76.447  121.207 1.00 8.52  ? 26   GLY B N   1 
ATOM   3975  C CA  . GLY B 1 47  ? 93.931  77.045  121.776 1.00 8.52  ? 26   GLY B CA  1 
ATOM   3976  C C   . GLY B 1 47  ? 94.008  77.275  123.268 1.00 8.52  ? 26   GLY B C   1 
ATOM   3977  O O   . GLY B 1 47  ? 93.023  77.048  123.980 1.00 8.52  ? 26   GLY B O   1 
ATOM   3978  N N   . GLY B 1 48  ? 95.162  77.710  123.761 1.00 10.53 ? 27   GLY B N   1 
ATOM   3979  C CA  . GLY B 1 48  ? 95.293  78.021  125.168 1.00 10.53 ? 27   GLY B CA  1 
ATOM   3980  C C   . GLY B 1 48  ? 95.339  76.831  126.094 1.00 10.53 ? 27   GLY B C   1 
ATOM   3981  O O   . GLY B 1 48  ? 95.293  77.014  127.313 1.00 10.53 ? 27   GLY B O   1 
ATOM   3982  N N   . GLU B 1 49  ? 95.435  75.617  125.558 1.00 13.30 ? 28   GLU B N   1 
ATOM   3983  C CA  . GLU B 1 49  ? 95.423  74.406  126.360 1.00 13.30 ? 28   GLU B CA  1 
ATOM   3984  C C   . GLU B 1 49  ? 96.365  73.383  125.746 1.00 13.30 ? 28   GLU B C   1 
ATOM   3985  O O   . GLU B 1 49  ? 96.717  73.459  124.568 1.00 13.30 ? 28   GLU B O   1 
ATOM   3986  C CB  . GLU B 1 49  ? 94.013  73.815  126.468 1.00 13.30 ? 28   GLU B CB  1 
ATOM   3987  C CG  . GLU B 1 49  ? 93.421  73.404  125.134 1.00 13.30 ? 28   GLU B CG  1 
ATOM   3988  C CD  . GLU B 1 49  ? 92.201  72.521  125.283 1.00 13.30 ? 28   GLU B CD  1 
ATOM   3989  O OE1 . GLU B 1 49  ? 92.272  71.529  126.038 1.00 13.30 ? 28   GLU B OE1 1 
ATOM   3990  O OE2 . GLU B 1 49  ? 91.172  72.813  124.639 1.00 13.30 ? 28   GLU B OE2 1 
ATOM   3991  N N   . TRP B 1 50  ? 96.766  72.417  126.565 1.00 11.85 ? 29   TRP B N   1 
ATOM   3992  C CA  . TRP B 1 50  ? 97.701  71.381  126.150 1.00 11.85 ? 29   TRP B CA  1 
ATOM   3993  C C   . TRP B 1 50  ? 96.932  70.223  125.532 1.00 11.85 ? 29   TRP B C   1 
ATOM   3994  O O   . TRP B 1 50  ? 96.117  69.582  126.204 1.00 11.85 ? 29   TRP B O   1 
ATOM   3995  C CB  . TRP B 1 50  ? 98.534  70.918  127.340 1.00 11.85 ? 29   TRP B CB  1 
ATOM   3996  C CG  . TRP B 1 50  ? 99.455  71.981  127.804 1.00 11.85 ? 29   TRP B CG  1 
ATOM   3997  C CD1 . TRP B 1 50  ? 99.274  72.821  128.860 1.00 11.85 ? 29   TRP B CD1 1 
ATOM   3998  C CD2 . TRP B 1 50  ? 100.696 72.351  127.202 1.00 11.85 ? 29   TRP B CD2 1 
ATOM   3999  N NE1 . TRP B 1 50  ? 100.336 73.685  128.962 1.00 11.85 ? 29   TRP B NE1 1 
ATOM   4000  C CE2 . TRP B 1 50  ? 101.222 73.416  127.953 1.00 11.85 ? 29   TRP B CE2 1 
ATOM   4001  C CE3 . TRP B 1 50  ? 101.415 71.881  126.102 1.00 11.85 ? 29   TRP B CE3 1 
ATOM   4002  C CZ2 . TRP B 1 50  ? 102.433 74.016  127.641 1.00 11.85 ? 29   TRP B CZ2 1 
ATOM   4003  C CZ3 . TRP B 1 50  ? 102.615 72.477  125.796 1.00 11.85 ? 29   TRP B CZ3 1 
ATOM   4004  C CH2 . TRP B 1 50  ? 103.114 73.531  126.561 1.00 11.85 ? 29   TRP B CH2 1 
ATOM   4005  N N   . VAL B 1 51  ? 97.197  69.951  124.259 1.00 12.53 ? 30   VAL B N   1 
ATOM   4006  C CA  . VAL B 1 51  ? 96.446  68.975  123.483 1.00 12.53 ? 30   VAL B CA  1 
ATOM   4007  C C   . VAL B 1 51  ? 97.390  67.856  123.080 1.00 12.53 ? 30   VAL B C   1 
ATOM   4008  O O   . VAL B 1 51  ? 98.425  68.107  122.451 1.00 12.53 ? 30   VAL B O   1 
ATOM   4009  C CB  . VAL B 1 51  ? 95.802  69.611  122.244 1.00 12.53 ? 30   VAL B CB  1 
ATOM   4010  C CG1 . VAL B 1 51  ? 95.006  68.576  121.474 1.00 12.53 ? 30   VAL B CG1 1 
ATOM   4011  C CG2 . VAL B 1 51  ? 94.921  70.773  122.651 1.00 12.53 ? 30   VAL B CG2 1 
ATOM   4012  N N   . ALA B 1 52  ? 97.036  66.627  123.438 1.00 17.04 ? 31   ALA B N   1 
ATOM   4013  C CA  . ALA B 1 52  ? 97.794  65.480  122.981 1.00 17.04 ? 31   ALA B CA  1 
ATOM   4014  C C   . ALA B 1 52  ? 97.587  65.288  121.480 1.00 17.04 ? 31   ALA B C   1 
ATOM   4015  O O   . ALA B 1 52  ? 96.517  65.595  120.951 1.00 17.04 ? 31   ALA B O   1 
ATOM   4016  C CB  . ALA B 1 52  ? 97.367  64.224  123.733 1.00 17.04 ? 31   ALA B CB  1 
ATOM   4017  N N   . PRO B 1 53  ? 98.598  64.793  120.769 1.00 19.00 ? 32   PRO B N   1 
ATOM   4018  C CA  . PRO B 1 53  ? 98.432  64.571  119.330 1.00 19.00 ? 32   PRO B CA  1 
ATOM   4019  C C   . PRO B 1 53  ? 97.379  63.509  119.053 1.00 19.00 ? 32   PRO B C   1 
ATOM   4020  O O   . PRO B 1 53  ? 97.175  62.581  119.840 1.00 19.00 ? 32   PRO B O   1 
ATOM   4021  C CB  . PRO B 1 53  ? 99.824  64.119  118.877 1.00 19.00 ? 32   PRO B CB  1 
ATOM   4022  C CG  . PRO B 1 53  ? 100.459 63.575  120.104 1.00 19.00 ? 32   PRO B CG  1 
ATOM   4023  C CD  . PRO B 1 53  ? 99.933  64.393  121.240 1.00 19.00 ? 32   PRO B CD  1 
ATOM   4024  N N   . VAL B 1 54  ? 96.688  63.668  117.923 1.00 20.87 ? 33   VAL B N   1 
ATOM   4025  C CA  . VAL B 1 54  ? 95.650  62.711  117.554 1.00 20.87 ? 33   VAL B CA  1 
ATOM   4026  C C   . VAL B 1 54  ? 96.270  61.389  117.114 1.00 20.87 ? 33   VAL B C   1 
ATOM   4027  O O   . VAL B 1 54  ? 95.707  60.315  117.354 1.00 20.87 ? 33   VAL B O   1 
ATOM   4028  C CB  . VAL B 1 54  ? 94.724  63.312  116.479 1.00 20.87 ? 33   VAL B CB  1 
ATOM   4029  C CG1 . VAL B 1 54  ? 94.267  64.700  116.899 1.00 20.87 ? 33   VAL B CG1 1 
ATOM   4030  C CG2 . VAL B 1 54  ? 95.413  63.374  115.123 1.00 20.87 ? 33   VAL B CG2 1 
ATOM   4031  N N   . SER B 1 55  ? 97.437  61.441  116.471 1.00 23.06 ? 34   SER B N   1 
ATOM   4032  C CA  . SER B 1 55  ? 98.096  60.222  116.020 1.00 23.06 ? 34   SER B CA  1 
ATOM   4033  C C   . SER B 1 55  ? 98.745  59.448  117.158 1.00 23.06 ? 34   SER B C   1 
ATOM   4034  O O   . SER B 1 55  ? 99.168  58.307  116.945 1.00 23.06 ? 34   SER B O   1 
ATOM   4035  C CB  . SER B 1 55  ? 99.144  60.556  114.958 1.00 23.06 ? 34   SER B CB  1 
ATOM   4036  O OG  . SER B 1 55  ? 100.263 61.214  115.524 1.00 23.06 ? 34   SER B OG  1 
ATOM   4037  N N   . GLY B 1 56  ? 98.841  60.037  118.350 1.00 21.66 ? 35   GLY B N   1 
ATOM   4038  C CA  . GLY B 1 56  ? 99.418  59.372  119.497 1.00 21.66 ? 35   GLY B CA  1 
ATOM   4039  C C   . GLY B 1 56  ? 100.918 59.192  119.471 1.00 21.66 ? 35   GLY B C   1 
ATOM   4040  O O   . GLY B 1 56  ? 101.493 58.829  120.503 1.00 21.66 ? 35   GLY B O   1 
ATOM   4041  N N   . ARG B 1 57  ? 101.579 59.426  118.341 1.00 22.79 ? 36   ARG B N   1 
ATOM   4042  C CA  . ARG B 1 57  ? 103.019 59.245  118.303 1.00 22.79 ? 36   ARG B CA  1 
ATOM   4043  C C   . ARG B 1 57  ? 103.725 60.367  119.063 1.00 22.79 ? 36   ARG B C   1 
ATOM   4044  O O   . ARG B 1 57  ? 103.140 61.395  119.413 1.00 22.79 ? 36   ARG B O   1 
ATOM   4045  C CB  . ARG B 1 57  ? 103.531 59.183  116.866 1.00 22.79 ? 36   ARG B CB  1 
ATOM   4046  C CG  . ARG B 1 57  ? 102.889 58.116  116.003 1.00 22.79 ? 36   ARG B CG  1 
ATOM   4047  C CD  . ARG B 1 57  ? 103.787 57.780  114.813 1.00 22.79 ? 36   ARG B CD  1 
ATOM   4048  N NE  . ARG B 1 57  ? 103.909 58.835  113.802 1.00 22.79 ? 36   ARG B NE  1 
ATOM   4049  C CZ  . ARG B 1 57  ? 102.903 59.494  113.229 1.00 22.79 ? 36   ARG B CZ  1 
ATOM   4050  N NH1 . ARG B 1 57  ? 101.641 59.203  113.505 1.00 22.79 ? 36   ARG B NH1 1 
ATOM   4051  N NH2 . ARG B 1 57  ? 103.168 60.433  112.329 1.00 22.79 ? 36   ARG B NH2 1 
ATOM   4052  N N   . TYR B 1 58  ? 105.012 60.145  119.310 1.00 17.92 ? 37   TYR B N   1 
ATOM   4053  C CA  . TYR B 1 58  ? 105.861 61.071  120.039 1.00 17.92 ? 37   TYR B CA  1 
ATOM   4054  C C   . TYR B 1 58  ? 107.273 60.917  119.502 1.00 17.92 ? 37   TYR B C   1 
ATOM   4055  O O   . TYR B 1 58  ? 107.560 60.007  118.723 1.00 17.92 ? 37   TYR B O   1 
ATOM   4056  C CB  . TYR B 1 58  ? 105.825 60.800  121.544 1.00 17.92 ? 37   TYR B CB  1 
ATOM   4057  C CG  . TYR B 1 58  ? 104.690 61.467  122.279 1.00 17.92 ? 37   TYR B CG  1 
ATOM   4058  C CD1 . TYR B 1 58  ? 103.465 60.836  122.425 1.00 17.92 ? 37   TYR B CD1 1 
ATOM   4059  C CD2 . TYR B 1 58  ? 104.849 62.719  122.841 1.00 17.92 ? 37   TYR B CD2 1 
ATOM   4060  C CE1 . TYR B 1 58  ? 102.428 61.442  123.099 1.00 17.92 ? 37   TYR B CE1 1 
ATOM   4061  C CE2 . TYR B 1 58  ? 103.821 63.331  123.517 1.00 17.92 ? 37   TYR B CE2 1 
ATOM   4062  C CZ  . TYR B 1 58  ? 102.613 62.689  123.645 1.00 17.92 ? 37   TYR B CZ  1 
ATOM   4063  O OH  . TYR B 1 58  ? 101.586 63.302  124.324 1.00 17.92 ? 37   TYR B OH  1 
ATOM   4064  N N   . PHE B 1 59  ? 108.161 61.815  119.916 1.00 17.50 ? 38   PHE B N   1 
ATOM   4065  C CA  . PHE B 1 59  ? 109.565 61.638  119.583 1.00 17.50 ? 38   PHE B CA  1 
ATOM   4066  C C   . PHE B 1 59  ? 110.416 62.104  120.755 1.00 17.50 ? 38   PHE B C   1 
ATOM   4067  O O   . PHE B 1 59  ? 110.009 62.956  121.552 1.00 17.50 ? 38   PHE B O   1 
ATOM   4068  C CB  . PHE B 1 59  ? 109.950 62.364  118.283 1.00 17.50 ? 38   PHE B CB  1 
ATOM   4069  C CG  . PHE B 1 59  ? 109.880 63.860  118.366 1.00 17.50 ? 38   PHE B CG  1 
ATOM   4070  C CD1 . PHE B 1 59  ? 108.707 64.529  118.074 1.00 17.50 ? 38   PHE B CD1 1 
ATOM   4071  C CD2 . PHE B 1 59  ? 110.997 64.601  118.709 1.00 17.50 ? 38   PHE B CD2 1 
ATOM   4072  C CE1 . PHE B 1 59  ? 108.644 65.906  118.145 1.00 17.50 ? 38   PHE B CE1 1 
ATOM   4073  C CE2 . PHE B 1 59  ? 110.937 65.976  118.782 1.00 17.50 ? 38   PHE B CE2 1 
ATOM   4074  C CZ  . PHE B 1 59  ? 109.760 66.629  118.498 1.00 17.50 ? 38   PHE B CZ  1 
ATOM   4075  N N   . THR B 1 60  ? 111.604 61.518  120.852 1.00 20.06 ? 39   THR B N   1 
ATOM   4076  C CA  . THR B 1 60  ? 112.504 61.772  121.964 1.00 20.06 ? 39   THR B CA  1 
ATOM   4077  C C   . THR B 1 60  ? 113.302 63.042  121.715 1.00 20.06 ? 39   THR B C   1 
ATOM   4078  O O   . THR B 1 60  ? 113.764 63.294  120.599 1.00 20.06 ? 39   THR B O   1 
ATOM   4079  C CB  . THR B 1 60  ? 113.457 60.594  122.169 1.00 20.06 ? 39   THR B CB  1 
ATOM   4080  O OG1 . THR B 1 60  ? 114.299 60.451  121.018 1.00 20.06 ? 39   THR B OG1 1 
ATOM   4081  C CG2 . THR B 1 60  ? 112.676 59.308  122.371 1.00 20.06 ? 39   THR B CG2 1 
ATOM   4082  N N   . ASN B 1 61  ? 113.463 63.837  122.764 1.00 19.89 ? 40   ASN B N   1 
ATOM   4083  C CA  . ASN B 1 61  ? 114.239 65.063  122.707 1.00 19.89 ? 40   ASN B CA  1 
ATOM   4084  C C   . ASN B 1 61  ? 115.638 64.784  123.237 1.00 19.89 ? 40   ASN B C   1 
ATOM   4085  O O   . ASN B 1 61  ? 115.794 64.217  124.323 1.00 19.89 ? 40   ASN B O   1 
ATOM   4086  C CB  . ASN B 1 61  ? 113.563 66.165  123.522 1.00 19.89 ? 40   ASN B CB  1 
ATOM   4087  C CG  . ASN B 1 61  ? 114.065 67.540  123.166 1.00 19.89 ? 40   ASN B CG  1 
ATOM   4088  O OD1 . ASN B 1 61  ? 114.817 67.713  122.208 1.00 19.89 ? 40   ASN B OD1 1 
ATOM   4089  N ND2 . ASN B 1 61  ? 113.652 68.531  123.939 1.00 19.89 ? 40   ASN B ND2 1 
ATOM   4090  N N   . THR B 1 62  ? 116.646 65.178  122.470 1.00 19.48 ? 41   THR B N   1 
ATOM   4091  C CA  . THR B 1 62  ? 118.038 64.913  122.801 1.00 19.48 ? 41   THR B CA  1 
ATOM   4092  C C   . THR B 1 62  ? 118.725 66.220  123.165 1.00 19.48 ? 41   THR B C   1 
ATOM   4093  O O   . THR B 1 62  ? 118.715 67.168  122.374 1.00 19.48 ? 41   THR B O   1 
ATOM   4094  C CB  . THR B 1 62  ? 118.756 64.243  121.630 1.00 19.48 ? 41   THR B CB  1 
ATOM   4095  O OG1 . THR B 1 62  ? 118.325 62.883  121.515 1.00 19.48 ? 41   THR B OG1 1 
ATOM   4096  C CG2 . THR B 1 62  ? 120.258 64.281  121.832 1.00 19.48 ? 41   THR B CG2 1 
ATOM   4097  N N   . THR B 1 63  ? 119.315 66.270  124.350 1.00 20.05 ? 42   THR B N   1 
ATOM   4098  C CA  . THR B 1 63  ? 120.183 67.392  124.684 1.00 20.05 ? 42   THR B CA  1 
ATOM   4099  C C   . THR B 1 63  ? 121.541 67.201  124.016 1.00 20.05 ? 42   THR B C   1 
ATOM   4100  O O   . THR B 1 63  ? 122.149 66.137  124.152 1.00 20.05 ? 42   THR B O   1 
ATOM   4101  C CB  . THR B 1 63  ? 120.333 67.543  126.203 1.00 20.05 ? 42   THR B CB  1 
ATOM   4102  O OG1 . THR B 1 63  ? 121.204 68.641  126.499 1.00 20.05 ? 42   THR B OG1 1 
ATOM   4103  C CG2 . THR B 1 63  ? 120.861 66.270  126.856 1.00 20.05 ? 42   THR B CG2 1 
ATOM   4104  N N   . PRO B 1 64  ? 122.029 68.184  123.257 1.00 19.51 ? 43   PRO B N   1 
ATOM   4105  C CA  . PRO B 1 64  ? 123.285 67.994  122.527 1.00 19.51 ? 43   PRO B CA  1 
ATOM   4106  C C   . PRO B 1 64  ? 124.522 68.196  123.377 1.00 19.51 ? 43   PRO B C   1 
ATOM   4107  O O   . PRO B 1 64  ? 125.633 67.933  122.896 1.00 19.51 ? 43   PRO B O   1 
ATOM   4108  C CB  . PRO B 1 64  ? 123.194 69.048  121.428 1.00 19.51 ? 43   PRO B CB  1 
ATOM   4109  C CG  . PRO B 1 64  ? 122.439 70.155  122.068 1.00 19.51 ? 43   PRO B CG  1 
ATOM   4110  C CD  . PRO B 1 64  ? 121.465 69.525  123.031 1.00 19.51 ? 43   PRO B CD  1 
ATOM   4111  N N   . ILE B 1 65  ? 124.361 68.660  124.617 1.00 21.12 ? 44   ILE B N   1 
ATOM   4112  C CA  . ILE B 1 65  ? 125.490 68.767  125.533 1.00 21.12 ? 44   ILE B CA  1 
ATOM   4113  C C   . ILE B 1 65  ? 126.104 67.396  125.780 1.00 21.12 ? 44   ILE B C   1 
ATOM   4114  O O   . ILE B 1 65  ? 127.330 67.238  125.780 1.00 21.12 ? 44   ILE B O   1 
ATOM   4115  C CB  . ILE B 1 65  ? 125.040 69.432  126.846 1.00 21.12 ? 44   ILE B CB  1 
ATOM   4116  C CG1 . ILE B 1 65  ? 124.558 70.857  126.579 1.00 21.12 ? 44   ILE B CG1 1 
ATOM   4117  C CG2 . ILE B 1 65  ? 126.159 69.418  127.870 1.00 21.12 ? 44   ILE B CG2 1 
ATOM   4118  C CD1 . ILE B 1 65  ? 123.667 71.408  127.655 1.00 21.12 ? 44   ILE B CD1 1 
ATOM   4119  N N   . THR B 1 66  ? 125.261 66.383  125.989 1.00 22.48 ? 45   THR B N   1 
ATOM   4120  C CA  . THR B 1 66  ? 125.715 65.039  126.304 1.00 22.48 ? 45   THR B CA  1 
ATOM   4121  C C   . THR B 1 66  ? 125.224 63.974  125.333 1.00 22.48 ? 45   THR B C   1 
ATOM   4122  O O   . THR B 1 66  ? 125.749 62.856  125.356 1.00 22.48 ? 45   THR B O   1 
ATOM   4123  C CB  . THR B 1 66  ? 125.272 64.646  127.722 1.00 22.48 ? 45   THR B CB  1 
ATOM   4124  O OG1 . THR B 1 66  ? 123.847 64.523  127.758 1.00 22.48 ? 45   THR B OG1 1 
ATOM   4125  C CG2 . THR B 1 66  ? 125.685 65.702  128.715 1.00 22.48 ? 45   THR B CG2 1 
ATOM   4126  N N   . GLY B 1 67  ? 124.241 64.277  124.490 1.00 20.12 ? 46   GLY B N   1 
ATOM   4127  C CA  . GLY B 1 67  ? 123.642 63.286  123.624 1.00 20.12 ? 46   GLY B CA  1 
ATOM   4128  C C   . GLY B 1 67  ? 122.532 62.476  124.255 1.00 20.12 ? 46   GLY B C   1 
ATOM   4129  O O   . GLY B 1 67  ? 121.994 61.579  123.597 1.00 20.12 ? 46   GLY B O   1 
ATOM   4130  N N   . ALA B 1 68  ? 122.162 62.776  125.497 1.00 23.67 ? 47   ALA B N   1 
ATOM   4131  C CA  . ALA B 1 68  ? 121.200 61.987  126.256 1.00 23.67 ? 47   ALA B CA  1 
ATOM   4132  C C   . ALA B 1 68  ? 119.773 62.342  125.842 1.00 23.67 ? 47   ALA B C   1 
ATOM   4133  O O   . ALA B 1 68  ? 119.536 63.013  124.834 1.00 23.67 ? 47   ALA B O   1 
ATOM   4134  C CB  . ALA B 1 68  ? 121.419 62.196  127.751 1.00 23.67 ? 47   ALA B CB  1 
ATOM   4135  N N   . GLU B 1 69  ? 118.797 61.875  126.619 1.00 29.13 ? 48   GLU B N   1 
ATOM   4136  C CA  . GLU B 1 69  ? 117.386 62.127  126.371 1.00 29.13 ? 48   GLU B CA  1 
ATOM   4137  C C   . GLU B 1 69  ? 116.822 62.987  127.495 1.00 29.13 ? 48   GLU B C   1 
ATOM   4138  O O   . GLU B 1 69  ? 117.198 62.826  128.659 1.00 29.13 ? 48   GLU B O   1 
ATOM   4139  C CB  . GLU B 1 69  ? 116.603 60.814  126.265 1.00 29.13 ? 48   GLU B CB  1 
ATOM   4140  C CG  . GLU B 1 69  ? 115.095 60.983  126.229 1.00 29.13 ? 48   GLU B CG  1 
ATOM   4141  C CD  . GLU B 1 69  ? 114.363 59.660  126.151 1.00 29.13 ? 48   GLU B CD  1 
ATOM   4142  O OE1 . GLU B 1 69  ? 113.231 59.636  125.623 1.00 29.13 ? 48   GLU B OE1 1 
ATOM   4143  O OE2 . GLU B 1 69  ? 114.920 58.645  126.619 1.00 29.13 ? 48   GLU B OE2 1 
ATOM   4144  N N   . ILE B 1 70  ? 115.919 63.905  127.141 1.00 24.34 ? 49   ILE B N   1 
ATOM   4145  C CA  . ILE B 1 70  ? 115.394 64.884  128.083 1.00 24.34 ? 49   ILE B CA  1 
ATOM   4146  C C   . ILE B 1 70  ? 113.875 64.964  128.088 1.00 24.34 ? 49   ILE B C   1 
ATOM   4147  O O   . ILE B 1 70  ? 113.314 65.720  128.883 1.00 24.34 ? 49   ILE B O   1 
ATOM   4148  C CB  . ILE B 1 70  ? 116.003 66.278  127.824 1.00 24.34 ? 49   ILE B CB  1 
ATOM   4149  C CG1 . ILE B 1 70  ? 115.786 66.685  126.364 1.00 24.34 ? 49   ILE B CG1 1 
ATOM   4150  C CG2 . ILE B 1 70  ? 117.468 66.311  128.228 1.00 24.34 ? 49   ILE B CG2 1 
ATOM   4151  C CD1 . ILE B 1 70  ? 116.223 68.089  126.040 1.00 24.34 ? 49   ILE B CD1 1 
ATOM   4152  N N   . GLY B 1 71  ? 113.187 64.219  127.240 1.00 22.72 ? 50   GLY B N   1 
ATOM   4153  C CA  . GLY B 1 71  ? 111.741 64.177  127.318 1.00 22.72 ? 50   GLY B CA  1 
ATOM   4154  C C   . GLY B 1 71  ? 111.121 63.642  126.046 1.00 22.72 ? 50   GLY B C   1 
ATOM   4155  O O   . GLY B 1 71  ? 111.800 63.345  125.065 1.00 22.72 ? 50   GLY B O   1 
ATOM   4156  N N   . GLN B 1 72  ? 109.798 63.519  126.096 1.00 20.12 ? 51   GLN B N   1 
ATOM   4157  C CA  . GLN B 1 72  ? 108.988 63.121  124.955 1.00 20.12 ? 51   GLN B CA  1 
ATOM   4158  C C   . GLN B 1 72  ? 108.180 64.321  124.490 1.00 20.12 ? 51   GLN B C   1 
ATOM   4159  O O   . GLN B 1 72  ? 107.511 64.972  125.298 1.00 20.12 ? 51   GLN B O   1 
ATOM   4160  C CB  . GLN B 1 72  ? 108.053 61.964  125.312 1.00 20.12 ? 51   GLN B CB  1 
ATOM   4161  C CG  . GLN B 1 72  ? 108.736 60.617  125.430 1.00 20.12 ? 51   GLN B CG  1 
ATOM   4162  C CD  . GLN B 1 72  ? 108.768 59.866  124.115 1.00 20.12 ? 51   GLN B CD  1 
ATOM   4163  O OE1 . GLN B 1 72  ? 109.733 59.954  123.359 1.00 20.12 ? 51   GLN B OE1 1 
ATOM   4164  N NE2 . GLN B 1 72  ? 107.708 59.117  123.838 1.00 20.12 ? 51   GLN B NE2 1 
ATOM   4165  N N   . ILE B 1 73  ? 108.240 64.612  123.195 1.00 17.90 ? 52   ILE B N   1 
ATOM   4166  C CA  . ILE B 1 73  ? 107.553 65.762  122.628 1.00 17.90 ? 52   ILE B CA  1 
ATOM   4167  C C   . ILE B 1 73  ? 106.656 65.279  121.497 1.00 17.90 ? 52   ILE B C   1 
ATOM   4168  O O   . ILE B 1 73  ? 107.039 64.400  120.718 1.00 17.90 ? 52   ILE B O   1 
ATOM   4169  C CB  . ILE B 1 73  ? 108.554 66.836  122.154 1.00 17.90 ? 52   ILE B CB  1 
ATOM   4170  C CG1 . ILE B 1 73  ? 109.085 67.596  123.369 1.00 17.90 ? 52   ILE B CG1 1 
ATOM   4171  C CG2 . ILE B 1 73  ? 107.908 67.802  121.185 1.00 17.90 ? 52   ILE B CG2 1 
ATOM   4172  C CD1 . ILE B 1 73  ? 110.086 68.657  123.047 1.00 17.90 ? 52   ILE B CD1 1 
ATOM   4173  N N   . ALA B 1 74  ? 105.450 65.844  121.432 1.00 17.50 ? 53   ALA B N   1 
ATOM   4174  C CA  . ALA B 1 74  ? 104.409 65.336  120.550 1.00 17.50 ? 53   ALA B CA  1 
ATOM   4175  C C   . ALA B 1 74  ? 104.838 65.377  119.094 1.00 17.50 ? 53   ALA B C   1 
ATOM   4176  O O   . ALA B 1 74  ? 105.364 66.382  118.612 1.00 17.50 ? 53   ALA B O   1 
ATOM   4177  C CB  . ALA B 1 74  ? 103.128 66.145  120.734 1.00 17.50 ? 53   ALA B CB  1 
ATOM   4178  N N   . ARG B 1 75  ? 104.605 64.275  118.394 1.00 21.56 ? 54   ARG B N   1 
ATOM   4179  C CA  . ARG B 1 75  ? 104.782 64.213  116.951 1.00 21.56 ? 54   ARG B CA  1 
ATOM   4180  C C   . ARG B 1 75  ? 103.417 64.427  116.316 1.00 21.56 ? 54   ARG B C   1 
ATOM   4181  O O   . ARG B 1 75  ? 102.475 63.674  116.582 1.00 21.56 ? 54   ARG B O   1 
ATOM   4182  C CB  . ARG B 1 75  ? 105.387 62.877  116.533 1.00 21.56 ? 54   ARG B CB  1 
ATOM   4183  C CG  . ARG B 1 75  ? 106.099 62.924  115.203 1.00 21.56 ? 54   ARG B CG  1 
ATOM   4184  C CD  . ARG B 1 75  ? 106.982 61.714  115.014 1.00 21.56 ? 54   ARG B CD  1 
ATOM   4185  N NE  . ARG B 1 75  ? 106.970 61.250  113.632 1.00 21.56 ? 54   ARG B NE  1 
ATOM   4186  C CZ  . ARG B 1 75  ? 107.040 59.974  113.272 1.00 21.56 ? 54   ARG B CZ  1 
ATOM   4187  N NH1 . ARG B 1 75  ? 107.128 59.027  114.196 1.00 21.56 ? 54   ARG B NH1 1 
ATOM   4188  N NH2 . ARG B 1 75  ? 107.021 59.645  111.989 1.00 21.56 ? 54   ARG B NH2 1 
ATOM   4189  N N   . SER B 1 76  ? 103.305 65.456  115.488 1.00 21.00 ? 55   SER B N   1 
ATOM   4190  C CA  . SER B 1 76  ? 102.034 65.841  114.906 1.00 21.00 ? 55   SER B CA  1 
ATOM   4191  C C   . SER B 1 76  ? 102.130 65.840  113.388 1.00 21.00 ? 55   SER B C   1 
ATOM   4192  O O   . SER B 1 76  ? 103.218 65.877  112.806 1.00 21.00 ? 55   SER B O   1 
ATOM   4193  C CB  . SER B 1 76  ? 101.596 67.217  115.405 1.00 21.00 ? 55   SER B CB  1 
ATOM   4194  O OG  . SER B 1 76  ? 102.495 68.215  114.967 1.00 21.00 ? 55   SER B OG  1 
ATOM   4195  N N   . GLU B 1 77  ? 100.966 65.797  112.755 1.00 23.20 ? 56   GLU B N   1 
ATOM   4196  C CA  . GLU B 1 77  ? 100.863 65.693  111.308 1.00 23.20 ? 56   GLU B CA  1 
ATOM   4197  C C   . GLU B 1 77  ? 99.735  66.616  110.864 1.00 23.20 ? 56   GLU B C   1 
ATOM   4198  O O   . GLU B 1 77  ? 99.317  67.519  111.597 1.00 23.20 ? 56   GLU B O   1 
ATOM   4199  C CB  . GLU B 1 77  ? 100.660 64.231  110.891 1.00 23.20 ? 56   GLU B CB  1 
ATOM   4200  C CG  . GLU B 1 77  ? 99.685  63.474  111.775 1.00 23.20 ? 56   GLU B CG  1 
ATOM   4201  C CD  . GLU B 1 77  ? 99.629  61.999  111.444 1.00 23.20 ? 56   GLU B CD  1 
ATOM   4202  O OE1 . GLU B 1 77  ? 100.556 61.506  110.766 1.00 23.20 ? 56   GLU B OE1 1 
ATOM   4203  O OE2 . GLU B 1 77  ? 98.656  61.334  111.858 1.00 23.20 ? 56   GLU B OE2 1 
ATOM   4204  N N   . ALA B 1 78  ? 99.212  66.381  109.663 1.00 19.90 ? 57   ALA B N   1 
ATOM   4205  C CA  . ALA B 1 78  ? 98.230  67.272  109.059 1.00 19.90 ? 57   ALA B CA  1 
ATOM   4206  C C   . ALA B 1 78  ? 96.908  67.281  109.819 1.00 19.90 ? 57   ALA B C   1 
ATOM   4207  O O   . ALA B 1 78  ? 95.952  67.934  109.392 1.00 19.90 ? 57   ALA B O   1 
ATOM   4208  C CB  . ALA B 1 78  ? 97.995  66.883  107.600 1.00 19.90 ? 57   ALA B CB  1 
ATOM   4209  N N   . GLY B 1 79  ? 96.838  66.561  110.936 1.00 18.86 ? 58   GLY B N   1 
ATOM   4210  C CA  . GLY B 1 79  ? 95.646  66.554  111.761 1.00 18.86 ? 58   GLY B CA  1 
ATOM   4211  C C   . GLY B 1 79  ? 95.700  67.551  112.899 1.00 18.86 ? 58   GLY B C   1 
ATOM   4212  O O   . GLY B 1 79  ? 94.697  68.203  113.201 1.00 18.86 ? 58   GLY B O   1 
ATOM   4213  N N   . ASP B 1 80  ? 96.858  67.673  113.552 1.00 18.08 ? 59   ASP B N   1 
ATOM   4214  C CA  . ASP B 1 80  ? 97.036  68.712  114.559 1.00 18.08 ? 59   ASP B CA  1 
ATOM   4215  C C   . ASP B 1 80  ? 97.322  70.070  113.944 1.00 18.08 ? 59   ASP B C   1 
ATOM   4216  O O   . ASP B 1 80  ? 97.056  71.094  114.582 1.00 18.08 ? 59   ASP B O   1 
ATOM   4217  C CB  . ASP B 1 80  ? 98.165  68.350  115.520 1.00 18.08 ? 59   ASP B CB  1 
ATOM   4218  C CG  . ASP B 1 80  ? 97.782  67.251  116.477 1.00 18.08 ? 59   ASP B CG  1 
ATOM   4219  O OD1 . ASP B 1 80  ? 96.975  66.382  116.092 1.00 18.08 ? 59   ASP B OD1 1 
ATOM   4220  O OD2 . ASP B 1 80  ? 98.288  67.261  117.617 1.00 18.08 ? 59   ASP B OD2 1 
ATOM   4221  N N   . ILE B 1 81  ? 97.860  70.100  112.726 1.00 17.65 ? 60   ILE B N   1 
ATOM   4222  C CA  . ILE B 1 81  ? 97.967  71.357  111.997 1.00 17.65 ? 60   ILE B CA  1 
ATOM   4223  C C   . ILE B 1 81  ? 96.590  71.978  111.834 1.00 17.65 ? 60   ILE B C   1 
ATOM   4224  O O   . ILE B 1 81  ? 96.399  73.177  112.065 1.00 17.65 ? 60   ILE B O   1 
ATOM   4225  C CB  . ILE B 1 81  ? 98.648  71.126  110.638 1.00 17.65 ? 60   ILE B CB  1 
ATOM   4226  C CG1 . ILE B 1 81  ? 100.089 70.682  110.853 1.00 17.65 ? 60   ILE B CG1 1 
ATOM   4227  C CG2 . ILE B 1 81  ? 98.604  72.379  109.795 1.00 17.65 ? 60   ILE B CG2 1 
ATOM   4228  C CD1 . ILE B 1 81  ? 100.829 71.548  111.827 1.00 17.65 ? 60   ILE B CD1 1 
ATOM   4229  N N   . GLU B 1 82  ? 95.602  71.163  111.465 1.00 16.37 ? 61   GLU B N   1 
ATOM   4230  C CA  . GLU B 1 82  ? 94.250  71.676  111.308 1.00 16.37 ? 61   GLU B CA  1 
ATOM   4231  C C   . GLU B 1 82  ? 93.629  72.050  112.644 1.00 16.37 ? 61   GLU B C   1 
ATOM   4232  O O   . GLU B 1 82  ? 92.846  72.998  112.705 1.00 16.37 ? 61   GLU B O   1 
ATOM   4233  C CB  . GLU B 1 82  ? 93.382  70.660  110.575 1.00 16.37 ? 61   GLU B CB  1 
ATOM   4234  C CG  . GLU B 1 82  ? 93.823  70.441  109.142 1.00 16.37 ? 61   GLU B CG  1 
ATOM   4235  C CD  . GLU B 1 82  ? 93.626  71.673  108.281 1.00 16.37 ? 61   GLU B CD  1 
ATOM   4236  O OE1 . GLU B 1 82  ? 92.674  72.441  108.539 1.00 16.37 ? 61   GLU B OE1 1 
ATOM   4237  O OE2 . GLU B 1 82  ? 94.435  71.880  107.353 1.00 16.37 ? 61   GLU B OE2 1 
ATOM   4238  N N   . LEU B 1 83  ? 93.962  71.339  113.723 1.00 13.05 ? 62   LEU B N   1 
ATOM   4239  C CA  . LEU B 1 83  ? 93.483  71.750  115.040 1.00 13.05 ? 62   LEU B CA  1 
ATOM   4240  C C   . LEU B 1 83  ? 94.016  73.127  115.410 1.00 13.05 ? 62   LEU B C   1 
ATOM   4241  O O   . LEU B 1 83  ? 93.269  73.989  115.901 1.00 13.05 ? 62   LEU B O   1 
ATOM   4242  C CB  . LEU B 1 83  ? 93.896  70.724  116.093 1.00 13.05 ? 62   LEU B CB  1 
ATOM   4243  C CG  . LEU B 1 83  ? 92.977  69.524  116.319 1.00 13.05 ? 62   LEU B CG  1 
ATOM   4244  C CD1 . LEU B 1 83  ? 93.705  68.455  117.106 1.00 13.05 ? 62   LEU B CD1 1 
ATOM   4245  C CD2 . LEU B 1 83  ? 91.723  69.957  117.042 1.00 13.05 ? 62   LEU B CD2 1 
ATOM   4246  N N   . ALA B 1 84  ? 95.310  73.350  115.173 1.00 9.91  ? 63   ALA B N   1 
ATOM   4247  C CA  . ALA B 1 84  ? 95.907  74.653  115.436 1.00 9.91  ? 63   ALA B CA  1 
ATOM   4248  C C   . ALA B 1 84  ? 95.251  75.731  114.589 1.00 9.91  ? 63   ALA B C   1 
ATOM   4249  O O   . ALA B 1 84  ? 94.936  76.818  115.084 1.00 9.91  ? 63   ALA B O   1 
ATOM   4250  C CB  . ALA B 1 84  ? 97.408  74.600  115.171 1.00 9.91  ? 63   ALA B CB  1 
ATOM   4251  N N   . LEU B 1 85  ? 95.031  75.444  113.305 1.00 10.83 ? 64   LEU B N   1 
ATOM   4252  C CA  . LEU B 1 85  ? 94.402  76.430  112.433 1.00 10.83 ? 64   LEU B CA  1 
ATOM   4253  C C   . LEU B 1 85  ? 92.975  76.728  112.873 1.00 10.83 ? 64   LEU B C   1 
ATOM   4254  O O   . LEU B 1 85  ? 92.520  77.870  112.781 1.00 10.83 ? 64   LEU B O   1 
ATOM   4255  C CB  . LEU B 1 85  ? 94.431  75.955  110.984 1.00 10.83 ? 64   LEU B CB  1 
ATOM   4256  C CG  . LEU B 1 85  ? 95.811  75.828  110.347 1.00 10.83 ? 64   LEU B CG  1 
ATOM   4257  C CD1 . LEU B 1 85  ? 95.825  74.708  109.337 1.00 10.83 ? 64   LEU B CD1 1 
ATOM   4258  C CD2 . LEU B 1 85  ? 96.194  77.116  109.689 1.00 10.83 ? 64   LEU B CD2 1 
ATOM   4259  N N   . ASP B 1 86  ? 92.252  75.717  113.352 1.00 12.45 ? 65   ASP B N   1 
ATOM   4260  C CA  . ASP B 1 86  ? 90.887  75.941  113.812 1.00 12.45 ? 65   ASP B CA  1 
ATOM   4261  C C   . ASP B 1 86  ? 90.863  76.836  115.043 1.00 12.45 ? 65   ASP B C   1 
ATOM   4262  O O   . ASP B 1 86  ? 90.059  77.772  115.124 1.00 12.45 ? 65   ASP B O   1 
ATOM   4263  C CB  . ASP B 1 86  ? 90.203  74.606  114.099 1.00 12.45 ? 65   ASP B CB  1 
ATOM   4264  C CG  . ASP B 1 86  ? 90.041  73.758  112.855 1.00 12.45 ? 65   ASP B CG  1 
ATOM   4265  O OD1 . ASP B 1 86  ? 90.003  74.332  111.747 1.00 12.45 ? 65   ASP B OD1 1 
ATOM   4266  O OD2 . ASP B 1 86  ? 89.962  72.518  112.982 1.00 12.45 ? 65   ASP B OD2 1 
ATOM   4267  N N   . ALA B 1 87  ? 91.745  76.572  116.010 1.00 9.80  ? 66   ALA B N   1 
ATOM   4268  C CA  . ALA B 1 87  ? 91.822  77.453  117.174 1.00 9.80  ? 66   ALA B CA  1 
ATOM   4269  C C   . ALA B 1 87  ? 92.213  78.870  116.766 1.00 9.80  ? 66   ALA B C   1 
ATOM   4270  O O   . ALA B 1 87  ? 91.624  79.853  117.239 1.00 9.80  ? 66   ALA B O   1 
ATOM   4271  C CB  . ALA B 1 87  ? 92.811  76.897  118.193 1.00 9.80  ? 66   ALA B CB  1 
ATOM   4272  N N   . ALA B 1 88  ? 93.194  78.991  115.868 1.00 8.13  ? 67   ALA B N   1 
ATOM   4273  C CA  . ALA B 1 88  ? 93.648  80.303  115.429 1.00 8.13  ? 67   ALA B CA  1 
ATOM   4274  C C   . ALA B 1 88  ? 92.535  81.074  114.737 1.00 8.13  ? 67   ALA B C   1 
ATOM   4275  O O   . ALA B 1 88  ? 92.357  82.269  114.984 1.00 8.13  ? 67   ALA B O   1 
ATOM   4276  C CB  . ALA B 1 88  ? 94.851  80.155  114.501 1.00 8.13  ? 67   ALA B CB  1 
ATOM   4277  N N   . HIS B 1 89  ? 91.779  80.411  113.862 1.00 9.07  ? 68   HIS B N   1 
ATOM   4278  C CA  . HIS B 1 89  ? 90.710  81.097  113.149 1.00 9.07  ? 68   HIS B CA  1 
ATOM   4279  C C   . HIS B 1 89  ? 89.536  81.405  114.063 1.00 9.07  ? 68   HIS B C   1 
ATOM   4280  O O   . HIS B 1 89  ? 88.824  82.390  113.840 1.00 9.07  ? 68   HIS B O   1 
ATOM   4281  C CB  . HIS B 1 89  ? 90.257  80.264  111.956 1.00 9.07  ? 68   HIS B CB  1 
ATOM   4282  C CG  . HIS B 1 89  ? 91.133  80.412  110.754 1.00 9.07  ? 68   HIS B CG  1 
ATOM   4283  N ND1 . HIS B 1 89  ? 91.028  81.475  109.886 1.00 9.07  ? 68   HIS B ND1 1 
ATOM   4284  C CD2 . HIS B 1 89  ? 92.133  79.636  110.279 1.00 9.07  ? 68   HIS B CD2 1 
ATOM   4285  C CE1 . HIS B 1 89  ? 91.924  81.346  108.925 1.00 9.07  ? 68   HIS B CE1 1 
ATOM   4286  N NE2 . HIS B 1 89  ? 92.608  80.238  109.140 1.00 9.07  ? 68   HIS B NE2 1 
ATOM   4287  N N   . ALA B 1 90  ? 89.314  80.586  115.089 1.00 9.44  ? 69   ALA B N   1 
ATOM   4288  C CA  . ALA B 1 90  ? 88.278  80.905  116.059 1.00 9.44  ? 69   ALA B CA  1 
ATOM   4289  C C   . ALA B 1 90  ? 88.685  82.043  116.983 1.00 9.44  ? 69   ALA B C   1 
ATOM   4290  O O   . ALA B 1 90  ? 87.817  82.638  117.626 1.00 9.44  ? 69   ALA B O   1 
ATOM   4291  C CB  . ALA B 1 90  ? 87.926  79.666  116.879 1.00 9.44  ? 69   ALA B CB  1 
ATOM   4292  N N   . ALA B 1 91  ? 89.980  82.349  117.076 1.00 8.34  ? 70   ALA B N   1 
ATOM   4293  C CA  . ALA B 1 91  ? 90.426  83.470  117.897 1.00 8.34  ? 70   ALA B CA  1 
ATOM   4294  C C   . ALA B 1 91  ? 90.808  84.718  117.103 1.00 8.34  ? 70   ALA B C   1 
ATOM   4295  O O   . ALA B 1 91  ? 91.000  85.777  117.713 1.00 8.34  ? 70   ALA B O   1 
ATOM   4296  C CB  . ALA B 1 91  ? 91.617  83.049  118.762 1.00 8.34  ? 70   ALA B CB  1 
ATOM   4297  N N   . LYS B 1 92  ? 90.935  84.620  115.775 1.00 8.71  ? 71   LYS B N   1 
ATOM   4298  C CA  . LYS B 1 92  ? 91.463  85.735  114.990 1.00 8.71  ? 71   LYS B CA  1 
ATOM   4299  C C   . LYS B 1 92  ? 90.527  86.935  114.995 1.00 8.71  ? 71   LYS B C   1 
ATOM   4300  O O   . LYS B 1 92  ? 90.986  88.082  115.061 1.00 8.71  ? 71   LYS B O   1 
ATOM   4301  C CB  . LYS B 1 92  ? 91.754  85.285  113.556 1.00 8.71  ? 71   LYS B CB  1 
ATOM   4302  C CG  . LYS B 1 92  ? 90.529  84.923  112.737 1.00 8.71  ? 71   LYS B CG  1 
ATOM   4303  C CD  . LYS B 1 92  ? 90.874  84.640  111.289 1.00 8.71  ? 71   LYS B CD  1 
ATOM   4304  C CE  . LYS B 1 92  ? 91.003  85.921  110.495 1.00 8.71  ? 71   LYS B CE  1 
ATOM   4305  N NZ  . LYS B 1 92  ? 91.049  85.653  109.032 1.00 8.71  ? 71   LYS B NZ  1 
ATOM   4306  N N   . GLU B 1 93  ? 89.216  86.701  114.926 1.00 10.08 ? 72   GLU B N   1 
ATOM   4307  C CA  . GLU B 1 93  ? 88.281  87.818  114.874 1.00 10.08 ? 72   GLU B CA  1 
ATOM   4308  C C   . GLU B 1 93  ? 88.261  88.594  116.182 1.00 10.08 ? 72   GLU B C   1 
ATOM   4309  O O   . GLU B 1 93  ? 88.119  89.820  116.169 1.00 10.08 ? 72   GLU B O   1 
ATOM   4310  C CB  . GLU B 1 93  ? 86.881  87.321  114.508 1.00 10.08 ? 72   GLU B CB  1 
ATOM   4311  C CG  . GLU B 1 93  ? 86.186  86.496  115.577 1.00 10.08 ? 72   GLU B CG  1 
ATOM   4312  C CD  . GLU B 1 93  ? 86.395  85.010  115.394 1.00 10.08 ? 72   GLU B CD  1 
ATOM   4313  O OE1 . GLU B 1 93  ? 87.551  84.555  115.503 1.00 10.08 ? 72   GLU B OE1 1 
ATOM   4314  O OE2 . GLU B 1 93  ? 85.404  84.296  115.137 1.00 10.08 ? 72   GLU B OE2 1 
ATOM   4315  N N   . LYS B 1 94  ? 88.403  87.908  117.315 1.00 8.34  ? 73   LYS B N   1 
ATOM   4316  C CA  . LYS B 1 94  ? 88.461  88.605  118.591 1.00 8.34  ? 73   LYS B CA  1 
ATOM   4317  C C   . LYS B 1 94  ? 89.818  89.249  118.828 1.00 8.34  ? 73   LYS B C   1 
ATOM   4318  O O   . LYS B 1 94  ? 89.891  90.294  119.482 1.00 8.34  ? 73   LYS B O   1 
ATOM   4319  C CB  . LYS B 1 94  ? 88.130  87.648  119.734 1.00 8.34  ? 73   LYS B CB  1 
ATOM   4320  C CG  . LYS B 1 94  ? 87.725  88.352  121.019 1.00 8.34  ? 73   LYS B CG  1 
ATOM   4321  C CD  . LYS B 1 94  ? 86.657  87.577  121.769 1.00 8.34  ? 73   LYS B CD  1 
ATOM   4322  C CE  . LYS B 1 94  ? 86.065  88.412  122.893 1.00 8.34  ? 73   LYS B CE  1 
ATOM   4323  N NZ  . LYS B 1 94  ? 84.652  88.039  123.175 1.00 8.34  ? 73   LYS B NZ  1 
ATOM   4324  N N   . TRP B 1 95  ? 90.898  88.651  118.318 1.00 4.00  ? 74   TRP B N   1 
ATOM   4325  C CA  . TRP B 1 95  ? 92.221  89.232  118.528 1.00 4.00  ? 74   TRP B CA  1 
ATOM   4326  C C   . TRP B 1 95  ? 92.407  90.497  117.703 1.00 4.00  ? 74   TRP B C   1 
ATOM   4327  O O   . TRP B 1 95  ? 92.900  91.510  118.208 1.00 4.00  ? 74   TRP B O   1 
ATOM   4328  C CB  . TRP B 1 95  ? 93.303  88.208  118.196 1.00 4.00  ? 74   TRP B CB  1 
ATOM   4329  C CG  . TRP B 1 95  ? 94.701  88.648  118.515 1.00 4.00  ? 74   TRP B CG  1 
ATOM   4330  C CD1 . TRP B 1 95  ? 95.768  88.616  117.677 1.00 4.00  ? 74   TRP B CD1 1 
ATOM   4331  C CD2 . TRP B 1 95  ? 95.190  89.156  119.764 1.00 4.00  ? 74   TRP B CD2 1 
ATOM   4332  N NE1 . TRP B 1 95  ? 96.887  89.082  118.313 1.00 4.00  ? 74   TRP B NE1 1 
ATOM   4333  C CE2 . TRP B 1 95  ? 96.558  89.420  119.597 1.00 4.00  ? 74   TRP B CE2 1 
ATOM   4334  C CE3 . TRP B 1 95  ? 94.604  89.414  121.004 1.00 4.00  ? 74   TRP B CE3 1 
ATOM   4335  C CZ2 . TRP B 1 95  ? 97.349  89.928  120.619 1.00 4.00  ? 74   TRP B CZ2 1 
ATOM   4336  C CZ3 . TRP B 1 95  ? 95.390  89.921  122.015 1.00 4.00  ? 74   TRP B CZ3 1 
ATOM   4337  C CH2 . TRP B 1 95  ? 96.748  90.173  121.817 1.00 4.00  ? 74   TRP B CH2 1 
ATOM   4338  N N   . GLY B 1 96  ? 92.009  90.465  116.430 1.00 6.11  ? 75   GLY B N   1 
ATOM   4339  C CA  . GLY B 1 96  ? 92.250  91.602  115.561 1.00 6.11  ? 75   GLY B CA  1 
ATOM   4340  C C   . GLY B 1 96  ? 91.396  92.811  115.867 1.00 6.11  ? 75   GLY B C   1 
ATOM   4341  O O   . GLY B 1 96  ? 91.686  93.902  115.369 1.00 6.11  ? 75   GLY B O   1 
ATOM   4342  N N   . ALA B 1 97  ? 90.349  92.645  116.667 1.00 6.69  ? 76   ALA B N   1 
ATOM   4343  C CA  . ALA B 1 97  ? 89.494  93.759  117.043 1.00 6.69  ? 76   ALA B CA  1 
ATOM   4344  C C   . ALA B 1 97  ? 89.913  94.417  118.349 1.00 6.69  ? 76   ALA B C   1 
ATOM   4345  O O   . ALA B 1 97  ? 89.350  95.455  118.709 1.00 6.69  ? 76   ALA B O   1 
ATOM   4346  C CB  . ALA B 1 97  ? 88.039  93.296  117.148 1.00 6.69  ? 76   ALA B CB  1 
ATOM   4347  N N   . THR B 1 98  ? 90.873  93.842  119.065 1.00 4.93  ? 77   THR B N   1 
ATOM   4348  C CA  . THR B 1 98  ? 91.415  94.491  120.247 1.00 4.93  ? 77   THR B CA  1 
ATOM   4349  C C   . THR B 1 98  ? 92.211  95.729  119.856 1.00 4.93  ? 77   THR B C   1 
ATOM   4350  O O   . THR B 1 98  ? 92.846  95.779  118.800 1.00 4.93  ? 77   THR B O   1 
ATOM   4351  C CB  . THR B 1 98  ? 92.305  93.531  121.032 1.00 4.93  ? 77   THR B CB  1 
ATOM   4352  O OG1 . THR B 1 98  ? 93.334  93.030  120.174 1.00 4.93  ? 77   THR B OG1 1 
ATOM   4353  C CG2 . THR B 1 98  ? 91.497  92.374  121.568 1.00 4.93  ? 77   THR B CG2 1 
ATOM   4354  N N   . SER B 1 99  ? 92.168  96.732  120.725 1.00 4.60  ? 78   SER B N   1 
ATOM   4355  C CA  . SER B 1 99  ? 92.882  97.971  120.480 1.00 4.60  ? 78   SER B CA  1 
ATOM   4356  C C   . SER B 1 99  ? 94.384  97.706  120.383 1.00 4.60  ? 78   SER B C   1 
ATOM   4357  O O   . SER B 1 99  ? 94.905  96.804  121.042 1.00 4.60  ? 78   SER B O   1 
ATOM   4358  C CB  . SER B 1 99  ? 92.596  98.966  121.600 1.00 4.60  ? 78   SER B CB  1 
ATOM   4359  O OG  . SER B 1 99  ? 93.462  100.081 121.541 1.00 4.60  ? 78   SER B OG  1 
ATOM   4360  N N   . PRO B 1 100 ? 95.104  98.466  119.555 1.00 4.22  ? 79   PRO B N   1 
ATOM   4361  C CA  . PRO B 1 100 ? 96.568  98.337  119.535 1.00 4.22  ? 79   PRO B CA  1 
ATOM   4362  C C   . PRO B 1 100 ? 97.223  98.667  120.864 1.00 4.22  ? 79   PRO B C   1 
ATOM   4363  O O   . PRO B 1 100 ? 98.338  98.199  121.117 1.00 4.22  ? 79   PRO B O   1 
ATOM   4364  C CB  . PRO B 1 100 ? 96.992  99.322  118.441 1.00 4.22  ? 79   PRO B CB  1 
ATOM   4365  C CG  . PRO B 1 100 ? 95.793  99.492  117.606 1.00 4.22  ? 79   PRO B CG  1 
ATOM   4366  C CD  . PRO B 1 100 ? 94.629  99.407  118.532 1.00 4.22  ? 79   PRO B CD  1 
ATOM   4367  N N   . ALA B 1 101 ? 96.579  99.465  121.716 1.00 4.32  ? 80   ALA B N   1 
ATOM   4368  C CA  . ALA B 1 101 ? 97.077  99.688  123.064 1.00 4.32  ? 80   ALA B CA  1 
ATOM   4369  C C   . ALA B 1 101 ? 96.781  98.529  124.002 1.00 4.32  ? 80   ALA B C   1 
ATOM   4370  O O   . ALA B 1 101 ? 97.388  98.451  125.073 1.00 4.32  ? 80   ALA B O   1 
ATOM   4371  C CB  . ALA B 1 101 ? 96.487  100.973 123.644 1.00 4.32  ? 80   ALA B CB  1 
ATOM   4372  N N   . GLU B 1 102 ? 95.859  97.640  123.643 1.00 4.79  ? 81   GLU B N   1 
ATOM   4373  C CA  . GLU B 1 102 ? 95.658  96.420  124.409 1.00 4.79  ? 81   GLU B CA  1 
ATOM   4374  C C   . GLU B 1 102 ? 96.585  95.304  123.961 1.00 4.79  ? 81   GLU B C   1 
ATOM   4375  O O   . GLU B 1 102 ? 96.917  94.426  124.762 1.00 4.79  ? 81   GLU B O   1 
ATOM   4376  C CB  . GLU B 1 102 ? 94.206  95.948  124.302 1.00 4.79  ? 81   GLU B CB  1 
ATOM   4377  C CG  . GLU B 1 102 ? 93.167  97.008  124.631 1.00 4.79  ? 81   GLU B CG  1 
ATOM   4378  C CD  . GLU B 1 102 ? 93.559  97.877  125.809 1.00 4.79  ? 81   GLU B CD  1 
ATOM   4379  O OE1 . GLU B 1 102 ? 93.549  99.118  125.664 1.00 4.79  ? 81   GLU B OE1 1 
ATOM   4380  O OE2 . GLU B 1 102 ? 93.869  97.321  126.883 1.00 4.79  ? 81   GLU B OE2 1 
ATOM   4381  N N   . ARG B 1 103 ? 97.007  95.318  122.702 1.00 2.97  ? 82   ARG B N   1 
ATOM   4382  C CA  . ARG B 1 103 ? 97.972  94.355  122.202 1.00 2.97  ? 82   ARG B CA  1 
ATOM   4383  C C   . ARG B 1 103 ? 99.403  94.747  122.517 1.00 2.97  ? 82   ARG B C   1 
ATOM   4384  O O   . ARG B 1 103 ? 100.317 93.967  122.235 1.00 2.97  ? 82   ARG B O   1 
ATOM   4385  C CB  . ARG B 1 103 ? 97.805  94.180  120.693 1.00 2.97  ? 82   ARG B CB  1 
ATOM   4386  C CG  . ARG B 1 103 ? 96.426  93.723  120.296 1.00 2.97  ? 82   ARG B CG  1 
ATOM   4387  C CD  . ARG B 1 103 ? 96.373  93.268  118.860 1.00 2.97  ? 82   ARG B CD  1 
ATOM   4388  N NE  . ARG B 1 103 ? 97.184  94.101  117.984 1.00 2.97  ? 82   ARG B NE  1 
ATOM   4389  C CZ  . ARG B 1 103 ? 96.688  94.954  117.099 1.00 2.97  ? 82   ARG B CZ  1 
ATOM   4390  N NH1 . ARG B 1 103 ? 95.380  95.092  116.975 1.00 2.97  ? 82   ARG B NH1 1 
ATOM   4391  N NH2 . ARG B 1 103 ? 97.501  95.667  116.338 1.00 2.97  ? 82   ARG B NH2 1 
ATOM   4392  N N   . ALA B 1 104 ? 99.618  95.933  123.082 1.00 3.62  ? 83   ALA B N   1 
ATOM   4393  C CA  . ALA B 1 104 ? 100.934 96.359  123.531 1.00 3.62  ? 83   ALA B CA  1 
ATOM   4394  C C   . ALA B 1 104 ? 101.142 96.157  125.020 1.00 3.62  ? 83   ALA B C   1 
ATOM   4395  O O   . ALA B 1 104 ? 102.251 95.821  125.438 1.00 3.62  ? 83   ALA B O   1 
ATOM   4396  C CB  . ALA B 1 104 ? 101.164 97.832  123.190 1.00 3.62  ? 83   ALA B CB  1 
ATOM   4397  N N   . ASN B 1 105 ? 100.101 96.345  125.830 1.00 4.05  ? 84   ASN B N   1 
ATOM   4398  C CA  . ASN B 1 105 ? 100.215 96.037  127.250 1.00 4.05  ? 84   ASN B CA  1 
ATOM   4399  C C   . ASN B 1 105 ? 100.423 94.546  127.471 1.00 4.05  ? 84   ASN B C   1 
ATOM   4400  O O   . ASN B 1 105 ? 101.181 94.144  128.360 1.00 4.05  ? 84   ASN B O   1 
ATOM   4401  C CB  . ASN B 1 105 ? 98.977  96.526  127.992 1.00 4.05  ? 84   ASN B CB  1 
ATOM   4402  C CG  . ASN B 1 105 ? 98.848  98.032  127.970 1.00 4.05  ? 84   ASN B CG  1 
ATOM   4403  O OD1 . ASN B 1 105 ? 99.699  98.730  127.424 1.00 4.05  ? 84   ASN B OD1 1 
ATOM   4404  N ND2 . ASN B 1 105 ? 97.778  98.541  128.567 1.00 4.05  ? 84   ASN B ND2 1 
ATOM   4405  N N   . ILE B 1 106 ? 99.775  93.709  126.663 1.00 3.63  ? 85   ILE B N   1 
ATOM   4406  C CA  . ILE B 1 106 ? 99.989  92.270  126.760 1.00 3.63  ? 85   ILE B CA  1 
ATOM   4407  C C   . ILE B 1 106 ? 101.418 91.915  126.373 1.00 3.63  ? 85   ILE B C   1 
ATOM   4408  O O   . ILE B 1 106 ? 102.046 91.052  126.995 1.00 3.63  ? 85   ILE B O   1 
ATOM   4409  C CB  . ILE B 1 106 ? 98.954  91.525  125.900 1.00 3.63  ? 85   ILE B CB  1 
ATOM   4410  C CG1 . ILE B 1 106 ? 97.580  91.599  126.564 1.00 3.63  ? 85   ILE B CG1 1 
ATOM   4411  C CG2 . ILE B 1 106 ? 99.362  90.085  125.692 1.00 3.63  ? 85   ILE B CG2 1 
ATOM   4412  C CD1 . ILE B 1 106 ? 96.440  91.226  125.657 1.00 3.63  ? 85   ILE B CD1 1 
ATOM   4413  N N   . MET B 1 107 ? 101.962 92.581  125.356 1.00 3.44  ? 86   MET B N   1 
ATOM   4414  C CA  . MET B 1 107 ? 103.350 92.343  124.971 1.00 3.44  ? 86   MET B CA  1 
ATOM   4415  C C   . MET B 1 107 ? 104.317 92.796  126.061 1.00 3.44  ? 86   MET B C   1 
ATOM   4416  O O   . MET B 1 107 ? 105.325 92.130  126.324 1.00 3.44  ? 86   MET B O   1 
ATOM   4417  C CB  . MET B 1 107 ? 103.644 93.057  123.658 1.00 3.44  ? 86   MET B CB  1 
ATOM   4418  C CG  . MET B 1 107 ? 103.347 92.231  122.433 1.00 3.44  ? 86   MET B CG  1 
ATOM   4419  S SD  . MET B 1 107 ? 103.579 93.174  120.923 1.00 3.44  ? 86   MET B SD  1 
ATOM   4420  C CE  . MET B 1 107 ? 105.220 92.653  120.464 1.00 3.44  ? 86   MET B CE  1 
ATOM   4421  N N   . LEU B 1 108 ? 104.031 93.929  126.702 1.00 3.70  ? 87   LEU B N   1 
ATOM   4422  C CA  . LEU B 1 108 ? 104.871 94.385  127.803 1.00 3.70  ? 87   LEU B CA  1 
ATOM   4423  C C   . LEU B 1 108 ? 104.806 93.424  128.982 1.00 3.70  ? 87   LEU B C   1 
ATOM   4424  O O   . LEU B 1 108 ? 105.817 93.188  129.652 1.00 3.70  ? 87   LEU B O   1 
ATOM   4425  C CB  . LEU B 1 108 ? 104.460 95.788  128.238 1.00 3.70  ? 87   LEU B CB  1 
ATOM   4426  C CG  . LEU B 1 108 ? 104.732 96.908  127.241 1.00 3.70  ? 87   LEU B CG  1 
ATOM   4427  C CD1 . LEU B 1 108 ? 104.398 98.241  127.863 1.00 3.70  ? 87   LEU B CD1 1 
ATOM   4428  C CD2 . LEU B 1 108 ? 106.171 96.875  126.768 1.00 3.70  ? 87   LEU B CD2 1 
ATOM   4429  N N   . LYS B 1 109 ? 103.629 92.861  129.255 1.00 3.87  ? 88   LYS B N   1 
ATOM   4430  C CA  . LYS B 1 109 ? 103.520 91.868  130.317 1.00 3.87  ? 88   LYS B CA  1 
ATOM   4431  C C   . LYS B 1 109 ? 104.268 90.591  129.954 1.00 3.87  ? 88   LYS B C   1 
ATOM   4432  O O   . LYS B 1 109 ? 104.884 89.956  130.818 1.00 3.87  ? 88   LYS B O   1 
ATOM   4433  C CB  . LYS B 1 109 ? 102.050 91.578  130.610 1.00 3.87  ? 88   LYS B CB  1 
ATOM   4434  C CG  . LYS B 1 109 ? 101.358 92.693  131.373 1.00 3.87  ? 88   LYS B CG  1 
ATOM   4435  C CD  . LYS B 1 109 ? 99.875  92.420  131.564 1.00 3.87  ? 88   LYS B CD  1 
ATOM   4436  C CE  . LYS B 1 109 ? 99.630  91.385  132.653 1.00 3.87  ? 88   LYS B CE  1 
ATOM   4437  N NZ  . LYS B 1 109 ? 100.120 91.838  133.980 1.00 3.87  ? 88   LYS B NZ  1 
ATOM   4438  N N   . ILE B 1 110 ? 104.238 90.207  128.678 1.00 4.00  ? 89   ILE B N   1 
ATOM   4439  C CA  . ILE B 1 110 ? 105.025 89.064  128.228 1.00 4.00  ? 89   ILE B CA  1 
ATOM   4440  C C   . ILE B 1 110 ? 106.506 89.319  128.458 1.00 4.00  ? 89   ILE B C   1 
ATOM   4441  O O   . ILE B 1 110 ? 107.237 88.442  128.928 1.00 4.00  ? 89   ILE B O   1 
ATOM   4442  C CB  . ILE B 1 110 ? 104.730 88.762  126.747 1.00 4.00  ? 89   ILE B CB  1 
ATOM   4443  C CG1 . ILE B 1 110 ? 103.389 88.051  126.595 1.00 4.00  ? 89   ILE B CG1 1 
ATOM   4444  C CG2 . ILE B 1 110 ? 105.839 87.934  126.132 1.00 4.00  ? 89   ILE B CG2 1 
ATOM   4445  C CD1 . ILE B 1 110 ? 103.079 87.681  125.167 1.00 4.00  ? 89   ILE B CD1 1 
ATOM   4446  N N   . ALA B 1 111 ? 106.971 90.523  128.131 1.00 4.44  ? 90   ALA B N   1 
ATOM   4447  C CA  . ALA B 1 111 ? 108.381 90.844  128.324 1.00 4.44  ? 90   ALA B CA  1 
ATOM   4448  C C   . ALA B 1 111 ? 108.748 90.876  129.802 1.00 4.44  ? 90   ALA B C   1 
ATOM   4449  O O   . ALA B 1 111 ? 109.832 90.427  130.186 1.00 4.44  ? 90   ALA B O   1 
ATOM   4450  C CB  . ALA B 1 111 ? 108.713 92.175  127.655 1.00 4.44  ? 90   ALA B CB  1 
ATOM   4451  N N   . ASP B 1 112 ? 107.857 91.395  130.647 1.00 6.54  ? 91   ASP B N   1 
ATOM   4452  C CA  . ASP B 1 112 ? 108.113 91.393  132.085 1.00 6.54  ? 91   ASP B CA  1 
ATOM   4453  C C   . ASP B 1 112 ? 108.224 89.972  132.625 1.00 6.54  ? 91   ASP B C   1 
ATOM   4454  O O   . ASP B 1 112 ? 109.113 89.674  133.432 1.00 6.54  ? 91   ASP B O   1 
ATOM   4455  C CB  . ASP B 1 112 ? 107.009 92.157  132.813 1.00 6.54  ? 91   ASP B CB  1 
ATOM   4456  C CG  . ASP B 1 112 ? 107.521 92.908  134.028 1.00 6.54  ? 91   ASP B CG  1 
ATOM   4457  O OD1 . ASP B 1 112 ? 108.295 92.322  134.814 1.00 6.54  ? 91   ASP B OD1 1 
ATOM   4458  O OD2 . ASP B 1 112 ? 107.146 94.087  134.198 1.00 6.54  ? 91   ASP B OD2 1 
ATOM   4459  N N   . ARG B 1 113 ? 107.334 89.079  132.188 1.00 6.43  ? 92   ARG B N   1 
ATOM   4460  C CA  . ARG B 1 113 ? 107.410 87.693  132.638 1.00 6.43  ? 92   ARG B CA  1 
ATOM   4461  C C   . ARG B 1 113 ? 108.667 87.006  132.121 1.00 6.43  ? 92   ARG B C   1 
ATOM   4462  O O   . ARG B 1 113 ? 109.307 86.245  132.854 1.00 6.43  ? 92   ARG B O   1 
ATOM   4463  C CB  . ARG B 1 113 ? 106.171 86.923  132.197 1.00 6.43  ? 92   ARG B CB  1 
ATOM   4464  C CG  . ARG B 1 113 ? 106.127 85.516  132.742 1.00 6.43  ? 92   ARG B CG  1 
ATOM   4465  C CD  . ARG B 1 113 ? 104.712 85.017  132.866 1.00 6.43  ? 92   ARG B CD  1 
ATOM   4466  N NE  . ARG B 1 113 ? 103.914 85.791  133.804 1.00 6.43  ? 92   ARG B NE  1 
ATOM   4467  C CZ  . ARG B 1 113 ? 102.588 85.768  133.835 1.00 6.43  ? 92   ARG B CZ  1 
ATOM   4468  N NH1 . ARG B 1 113 ? 101.922 85.011  132.975 1.00 6.43  ? 92   ARG B NH1 1 
ATOM   4469  N NH2 . ARG B 1 113 ? 101.928 86.499  134.722 1.00 6.43  ? 92   ARG B NH2 1 
ATOM   4470  N N   . MET B 1 114 ? 109.035 87.251  130.863 1.00 6.20  ? 93   MET B N   1 
ATOM   4471  C CA  . MET B 1 114 ? 110.254 86.669  130.318 1.00 6.20  ? 93   MET B CA  1 
ATOM   4472  C C   . MET B 1 114 ? 111.503 87.202  130.998 1.00 6.20  ? 93   MET B C   1 
ATOM   4473  O O   . MET B 1 114 ? 112.519 86.503  131.031 1.00 6.20  ? 93   MET B O   1 
ATOM   4474  C CB  . MET B 1 114 ? 110.354 86.945  128.822 1.00 6.20  ? 93   MET B CB  1 
ATOM   4475  C CG  . MET B 1 114 ? 109.353 86.217  127.967 1.00 6.20  ? 93   MET B CG  1 
ATOM   4476  S SD  . MET B 1 114 ? 109.624 86.610  126.235 1.00 6.20  ? 93   MET B SD  1 
ATOM   4477  C CE  . MET B 1 114 ? 111.325 86.108  126.050 1.00 6.20  ? 93   MET B CE  1 
ATOM   4478  N N   . GLU B 1 115 ? 111.458 88.429  131.514 1.00 7.73  ? 94   GLU B N   1 
ATOM   4479  C CA  . GLU B 1 115 ? 112.619 88.987  132.194 1.00 7.73  ? 94   GLU B CA  1 
ATOM   4480  C C   . GLU B 1 115 ? 112.715 88.491  133.630 1.00 7.73  ? 94   GLU B C   1 
ATOM   4481  O O   . GLU B 1 115 ? 113.817 88.250  134.132 1.00 7.73  ? 94   GLU B O   1 
ATOM   4482  C CB  . GLU B 1 115 ? 112.561 90.513  132.151 1.00 7.73  ? 94   GLU B CB  1 
ATOM   4483  C CG  . GLU B 1 115 ? 113.769 91.198  132.761 1.00 7.73  ? 94   GLU B CG  1 
ATOM   4484  C CD  . GLU B 1 115 ? 113.699 92.706  132.654 1.00 7.73  ? 94   GLU B CD  1 
ATOM   4485  O OE1 . GLU B 1 115 ? 112.694 93.221  132.122 1.00 7.73  ? 94   GLU B OE1 1 
ATOM   4486  O OE2 . GLU B 1 115 ? 114.651 93.379  133.102 1.00 7.73  ? 94   GLU B OE2 1 
ATOM   4487  N N   . ARG B 1 116 ? 111.574 88.327  134.304 1.00 8.31  ? 95   ARG B N   1 
ATOM   4488  C CA  . ARG B 1 116 ? 111.594 87.780  135.656 1.00 8.31  ? 95   ARG B CA  1 
ATOM   4489  C C   . ARG B 1 116 ? 112.120 86.349  135.684 1.00 8.31  ? 95   ARG B C   1 
ATOM   4490  O O   . ARG B 1 116 ? 112.700 85.925  136.688 1.00 8.31  ? 95   ARG B O   1 
ATOM   4491  C CB  . ARG B 1 116 ? 110.196 87.841  136.268 1.00 8.31  ? 95   ARG B CB  1 
ATOM   4492  C CG  . ARG B 1 116 ? 109.861 89.169  136.928 1.00 8.31  ? 95   ARG B CG  1 
ATOM   4493  C CD  . ARG B 1 116 ? 108.367 89.316  137.146 1.00 8.31  ? 95   ARG B CD  1 
ATOM   4494  N NE  . ARG B 1 116 ? 107.770 88.087  137.658 1.00 8.31  ? 95   ARG B NE  1 
ATOM   4495  C CZ  . ARG B 1 116 ? 106.816 87.403  137.036 1.00 8.31  ? 95   ARG B CZ  1 
ATOM   4496  N NH1 . ARG B 1 116 ? 106.344 87.828  135.871 1.00 8.31  ? 95   ARG B NH1 1 
ATOM   4497  N NH2 . ARG B 1 116 ? 106.333 86.293  137.576 1.00 8.31  ? 95   ARG B NH2 1 
ATOM   4498  N N   . ASN B 1 117 ? 111.939 85.599  134.600 1.00 8.57  ? 96   ASN B N   1 
ATOM   4499  C CA  . ASN B 1 117 ? 112.330 84.198  134.508 1.00 8.57  ? 96   ASN B CA  1 
ATOM   4500  C C   . ASN B 1 117 ? 113.413 83.999  133.457 1.00 8.57  ? 96   ASN B C   1 
ATOM   4501  O O   . ASN B 1 117 ? 113.375 83.051  132.673 1.00 8.57  ? 96   ASN B O   1 
ATOM   4502  C CB  . ASN B 1 117 ? 111.125 83.320  134.188 1.00 8.57  ? 96   ASN B CB  1 
ATOM   4503  C CG  . ASN B 1 117 ? 110.123 83.279  135.311 1.00 8.57  ? 96   ASN B CG  1 
ATOM   4504  O OD1 . ASN B 1 117 ? 110.205 82.431  136.195 1.00 8.57  ? 96   ASN B OD1 1 
ATOM   4505  N ND2 . ASN B 1 117 ? 109.170 84.199  135.288 1.00 8.57  ? 96   ASN B ND2 1 
ATOM   4506  N N   . LEU B 1 118 ? 114.395 84.901  133.426 1.00 10.52 ? 97   LEU B N   1 
ATOM   4507  C CA  . LEU B 1 118 ? 115.391 84.869  132.361 1.00 10.52 ? 97   LEU B CA  1 
ATOM   4508  C C   . LEU B 1 118 ? 116.297 83.651  132.464 1.00 10.52 ? 97   LEU B C   1 
ATOM   4509  O O   . LEU B 1 118 ? 116.793 83.168  131.443 1.00 10.52 ? 97   LEU B O   1 
ATOM   4510  C CB  . LEU B 1 118 ? 116.211 86.159  132.385 1.00 10.52 ? 97   LEU B CB  1 
ATOM   4511  C CG  . LEU B 1 118 ? 117.254 86.403  131.295 1.00 10.52 ? 97   LEU B CG  1 
ATOM   4512  C CD1 . LEU B 1 118 ? 117.297 87.871  130.939 1.00 10.52 ? 97   LEU B CD1 1 
ATOM   4513  C CD2 . LEU B 1 118 ? 118.625 85.951  131.755 1.00 10.52 ? 97   LEU B CD2 1 
ATOM   4514  N N   . GLU B 1 119 ? 116.525 83.144  133.676 1.00 12.18 ? 98   GLU B N   1 
ATOM   4515  C CA  . GLU B 1 119 ? 117.404 81.994  133.857 1.00 12.18 ? 98   GLU B CA  1 
ATOM   4516  C C   . GLU B 1 119 ? 116.744 80.696  133.407 1.00 12.18 ? 98   GLU B C   1 
ATOM   4517  O O   . GLU B 1 119 ? 117.393 79.862  132.765 1.00 12.18 ? 98   GLU B O   1 
ATOM   4518  C CB  . GLU B 1 119 ? 117.842 81.892  135.316 1.00 12.18 ? 98   GLU B CB  1 
ATOM   4519  C CG  . GLU B 1 119 ? 118.484 83.157  135.868 1.00 12.18 ? 98   GLU B CG  1 
ATOM   4520  C CD  . GLU B 1 119 ? 117.464 84.183  136.339 1.00 12.18 ? 98   GLU B CD  1 
ATOM   4521  O OE1 . GLU B 1 119 ? 117.868 85.320  136.665 1.00 12.18 ? 98   GLU B OE1 1 
ATOM   4522  O OE2 . GLU B 1 119 ? 116.259 83.855  136.375 1.00 12.18 ? 98   GLU B OE2 1 
ATOM   4523  N N   . LEU B 1 120 ? 115.464 80.503  133.736 1.00 10.73 ? 99   LEU B N   1 
ATOM   4524  C CA  . LEU B 1 120 ? 114.753 79.311  133.284 1.00 10.73 ? 99   LEU B CA  1 
ATOM   4525  C C   . LEU B 1 120 ? 114.779 79.203  131.767 1.00 10.73 ? 99   LEU B C   1 
ATOM   4526  O O   . LEU B 1 120 ? 115.078 78.141  131.212 1.00 10.73 ? 99   LEU B O   1 
ATOM   4527  C CB  . LEU B 1 120 ? 113.310 79.334  133.785 1.00 10.73 ? 99   LEU B CB  1 
ATOM   4528  C CG  . LEU B 1 120 ? 113.053 79.120  135.274 1.00 10.73 ? 99   LEU B CG  1 
ATOM   4529  C CD1 . LEU B 1 120 ? 113.029 80.443  136.020 1.00 10.73 ? 99   LEU B CD1 1 
ATOM   4530  C CD2 . LEU B 1 120 ? 111.752 78.364  135.469 1.00 10.73 ? 99   LEU B CD2 1 
ATOM   4531  N N   . LEU B 1 121 ? 114.459 80.297  131.079 1.00 9.74  ? 100  LEU B N   1 
ATOM   4532  C CA  . LEU B 1 121 ? 114.497 80.295  129.622 1.00 9.74  ? 100  LEU B CA  1 
ATOM   4533  C C   . LEU B 1 121 ? 115.920 80.131  129.109 1.00 9.74  ? 100  LEU B C   1 
ATOM   4534  O O   . LEU B 1 121 ? 116.154 79.423  128.123 1.00 9.74  ? 100  LEU B O   1 
ATOM   4535  C CB  . LEU B 1 121 ? 113.878 81.582  129.092 1.00 9.74  ? 100  LEU B CB  1 
ATOM   4536  C CG  . LEU B 1 121 ? 112.409 81.806  129.434 1.00 9.74  ? 100  LEU B CG  1 
ATOM   4537  C CD1 . LEU B 1 121 ? 112.090 83.277  129.432 1.00 9.74  ? 100  LEU B CD1 1 
ATOM   4538  C CD2 . LEU B 1 121 ? 111.551 81.090  128.426 1.00 9.74  ? 100  LEU B CD2 1 
ATOM   4539  N N   . ALA B 1 122 ? 116.884 80.777  129.766 1.00 11.90 ? 101  ALA B N   1 
ATOM   4540  C CA  . ALA B 1 122 ? 118.278 80.600  129.382 1.00 11.90 ? 101  ALA B CA  1 
ATOM   4541  C C   . ALA B 1 122 ? 118.714 79.154  129.563 1.00 11.90 ? 101  ALA B C   1 
ATOM   4542  O O   . ALA B 1 122 ? 119.379 78.584  128.693 1.00 11.90 ? 101  ALA B O   1 
ATOM   4543  C CB  . ALA B 1 122 ? 119.167 81.535  130.199 1.00 11.90 ? 101  ALA B CB  1 
ATOM   4544  N N   . THR B 1 123 ? 118.332 78.537  130.682 1.00 14.02 ? 102  THR B N   1 
ATOM   4545  C CA  . THR B 1 123 ? 118.701 77.148  130.927 1.00 14.02 ? 102  THR B CA  1 
ATOM   4546  C C   . THR B 1 123 ? 118.025 76.204  129.943 1.00 14.02 ? 102  THR B C   1 
ATOM   4547  O O   . THR B 1 123 ? 118.631 75.216  129.521 1.00 14.02 ? 102  THR B O   1 
ATOM   4548  C CB  . THR B 1 123 ? 118.345 76.754  132.359 1.00 14.02 ? 102  THR B CB  1 
ATOM   4549  O OG1 . THR B 1 123 ? 118.804 77.765  133.264 1.00 14.02 ? 102  THR B OG1 1 
ATOM   4550  C CG2 . THR B 1 123 ? 118.990 75.442  132.715 1.00 14.02 ? 102  THR B CG2 1 
ATOM   4551  N N   . ALA B 1 124 ? 116.778 76.485  129.568 1.00 13.48 ? 103  ALA B N   1 
ATOM   4552  C CA  . ALA B 1 124 ? 116.099 75.652  128.582 1.00 13.48 ? 103  ALA B CA  1 
ATOM   4553  C C   . ALA B 1 124 ? 116.766 75.763  127.217 1.00 13.48 ? 103  ALA B C   1 
ATOM   4554  O O   . ALA B 1 124 ? 117.040 74.750  126.561 1.00 13.48 ? 103  ALA B O   1 
ATOM   4555  C CB  . ALA B 1 124 ? 114.626 76.043  128.500 1.00 13.48 ? 103  ALA B CB  1 
ATOM   4556  N N   . GLU B 1 125 ? 117.039 76.991  126.773 1.00 15.56 ? 104  GLU B N   1 
ATOM   4557  C CA  . GLU B 1 125 ? 117.743 77.185  125.513 1.00 15.56 ? 104  GLU B CA  1 
ATOM   4558  C C   . GLU B 1 125 ? 119.154 76.623  125.558 1.00 15.56 ? 104  GLU B C   1 
ATOM   4559  O O   . GLU B 1 125 ? 119.721 76.320  124.506 1.00 15.56 ? 104  GLU B O   1 
ATOM   4560  C CB  . GLU B 1 125 ? 117.782 78.671  125.158 1.00 15.56 ? 104  GLU B CB  1 
ATOM   4561  C CG  . GLU B 1 125 ? 117.830 78.948  123.671 1.00 15.56 ? 104  GLU B CG  1 
ATOM   4562  C CD  . GLU B 1 125 ? 118.157 80.396  123.354 1.00 15.56 ? 104  GLU B CD  1 
ATOM   4563  O OE1 . GLU B 1 125 ? 118.698 80.655  122.257 1.00 15.56 ? 104  GLU B OE1 1 
ATOM   4564  O OE2 . GLU B 1 125 ? 117.875 81.272  124.199 1.00 15.56 ? 104  GLU B OE2 1 
ATOM   4565  N N   . THR B 1 126 ? 119.735 76.484  126.750 1.00 16.17 ? 105  THR B N   1 
ATOM   4566  C CA  . THR B 1 126 ? 121.048 75.866  126.868 1.00 16.17 ? 105  THR B CA  1 
ATOM   4567  C C   . THR B 1 126 ? 120.963 74.351  126.752 1.00 16.17 ? 105  THR B C   1 
ATOM   4568  O O   . THR B 1 126 ? 121.730 73.736  126.007 1.00 16.17 ? 105  THR B O   1 
ATOM   4569  C CB  . THR B 1 126 ? 121.694 76.256  128.194 1.00 16.17 ? 105  THR B CB  1 
ATOM   4570  O OG1 . THR B 1 126 ? 121.614 77.675  128.363 1.00 16.17 ? 105  THR B OG1 1 
ATOM   4571  C CG2 . THR B 1 126 ? 123.144 75.823  128.219 1.00 16.17 ? 105  THR B CG2 1 
ATOM   4572  N N   . TRP B 1 127 ? 120.040 73.733  127.488 1.00 18.87 ? 106  TRP B N   1 
ATOM   4573  C CA  . TRP B 1 127 ? 119.925 72.280  127.449 1.00 18.87 ? 106  TRP B CA  1 
ATOM   4574  C C   . TRP B 1 127 ? 119.497 71.788  126.075 1.00 18.87 ? 106  TRP B C   1 
ATOM   4575  O O   . TRP B 1 127 ? 120.045 70.806  125.564 1.00 18.87 ? 106  TRP B O   1 
ATOM   4576  C CB  . TRP B 1 127 ? 118.941 71.796  128.510 1.00 18.87 ? 106  TRP B CB  1 
ATOM   4577  C CG  . TRP B 1 127 ? 119.527 71.682  129.876 1.00 18.87 ? 106  TRP B CG  1 
ATOM   4578  C CD1 . TRP B 1 127 ? 119.708 72.686  130.777 1.00 18.87 ? 106  TRP B CD1 1 
ATOM   4579  C CD2 . TRP B 1 127 ? 120.004 70.491  130.503 1.00 18.87 ? 106  TRP B CD2 1 
ATOM   4580  N NE1 . TRP B 1 127 ? 120.269 72.196  131.928 1.00 18.87 ? 106  TRP B NE1 1 
ATOM   4581  C CE2 . TRP B 1 127 ? 120.460 70.848  131.785 1.00 18.87 ? 106  TRP B CE2 1 
ATOM   4582  C CE3 . TRP B 1 127 ? 120.089 69.156  130.104 1.00 18.87 ? 106  TRP B CE3 1 
ATOM   4583  C CZ2 . TRP B 1 127 ? 120.994 69.920  132.670 1.00 18.87 ? 106  TRP B CZ2 1 
ATOM   4584  C CZ3 . TRP B 1 127 ? 120.621 68.238  130.982 1.00 18.87 ? 106  TRP B CZ3 1 
ATOM   4585  C CH2 . TRP B 1 127 ? 121.065 68.622  132.251 1.00 18.87 ? 106  TRP B CH2 1 
ATOM   4586  N N   . ASP B 1 128 ? 118.515 72.450  125.457 1.00 17.38 ? 107  ASP B N   1 
ATOM   4587  C CA  . ASP B 1 128 ? 117.993 71.938  124.193 1.00 17.38 ? 107  ASP B CA  1 
ATOM   4588  C C   . ASP B 1 128 ? 118.910 72.250  123.015 1.00 17.38 ? 107  ASP B C   1 
ATOM   4589  O O   . ASP B 1 128 ? 119.025 71.441  122.089 1.00 17.38 ? 107  ASP B O   1 
ATOM   4590  C CB  . ASP B 1 128 ? 116.595 72.491  123.933 1.00 17.38 ? 107  ASP B CB  1 
ATOM   4591  C CG  . ASP B 1 128 ? 115.755 71.558  123.083 1.00 17.38 ? 107  ASP B CG  1 
ATOM   4592  O OD1 . ASP B 1 128 ? 116.208 70.425  122.821 1.00 17.38 ? 107  ASP B OD1 1 
ATOM   4593  O OD2 . ASP B 1 128 ? 114.651 71.959  122.665 1.00 17.38 ? 107  ASP B OD2 1 
ATOM   4594  N N   . ASN B 1 129 ? 119.561 73.410  123.021 1.00 16.64 ? 108  ASN B N   1 
ATOM   4595  C CA  . ASN B 1 129 ? 120.392 73.831  121.901 1.00 16.64 ? 108  ASN B CA  1 
ATOM   4596  C C   . ASN B 1 129 ? 121.873 73.573  122.145 1.00 16.64 ? 108  ASN B C   1 
ATOM   4597  O O   . ASN B 1 129 ? 122.627 73.383  121.186 1.00 16.64 ? 108  ASN B O   1 
ATOM   4598  C CB  . ASN B 1 129 ? 120.156 75.324  121.621 1.00 16.64 ? 108  ASN B CB  1 
ATOM   4599  C CG  . ASN B 1 129 ? 120.808 75.813  120.336 1.00 16.64 ? 108  ASN B CG  1 
ATOM   4600  O OD1 . ASN B 1 129 ? 120.698 76.974  119.953 1.00 16.64 ? 108  ASN B OD1 1 
ATOM   4601  N ND2 . ASN B 1 129 ? 121.503 74.909  119.665 1.00 16.64 ? 108  ASN B ND2 1 
ATOM   4602  N N   . GLY B 1 130 ? 122.296 73.511  123.402 1.00 16.86 ? 109  GLY B N   1 
ATOM   4603  C CA  . GLY B 1 130 ? 123.692 73.264  123.718 1.00 16.86 ? 109  GLY B CA  1 
ATOM   4604  C C   . GLY B 1 130 ? 124.629 74.401  123.379 1.00 16.86 ? 109  GLY B C   1 
ATOM   4605  O O   . GLY B 1 130 ? 125.746 74.159  122.906 1.00 16.86 ? 109  GLY B O   1 
ATOM   4606  N N   . LYS B 1 131 ? 124.206 75.630  123.609 1.00 15.93 ? 110  LYS B N   1 
ATOM   4607  C CA  . LYS B 1 131 ? 125.057 76.789  123.424 1.00 15.93 ? 110  LYS B CA  1 
ATOM   4608  C C   . LYS B 1 131 ? 125.417 77.382  124.783 1.00 15.93 ? 110  LYS B C   1 
ATOM   4609  O O   . LYS B 1 131 ? 124.691 77.175  125.758 1.00 15.93 ? 110  LYS B O   1 
ATOM   4610  C CB  . LYS B 1 131 ? 124.366 77.845  122.554 1.00 15.93 ? 110  LYS B CB  1 
ATOM   4611  C CG  . LYS B 1 131 ? 123.311 78.656  123.275 1.00 15.93 ? 110  LYS B CG  1 
ATOM   4612  C CD  . LYS B 1 131 ? 123.057 79.971  122.565 1.00 15.93 ? 110  LYS B CD  1 
ATOM   4613  C CE  . LYS B 1 131 ? 122.041 79.794  121.457 1.00 15.93 ? 110  LYS B CE  1 
ATOM   4614  N NZ  . LYS B 1 131 ? 120.720 79.381  121.989 1.00 15.93 ? 110  LYS B NZ  1 
ATOM   4615  N N   . PRO B 1 132 ? 126.534 78.105  124.885 1.00 17.46 ? 111  PRO B N   1 
ATOM   4616  C CA  . PRO B 1 132 ? 127.018 78.529  126.202 1.00 17.46 ? 111  PRO B CA  1 
ATOM   4617  C C   . PRO B 1 132 ? 125.974 79.313  126.978 1.00 17.46 ? 111  PRO B C   1 
ATOM   4618  O O   . PRO B 1 132 ? 125.216 80.104  126.415 1.00 17.46 ? 111  PRO B O   1 
ATOM   4619  C CB  . PRO B 1 132 ? 128.230 79.397  125.864 1.00 17.46 ? 111  PRO B CB  1 
ATOM   4620  C CG  . PRO B 1 132 ? 128.723 78.854  124.595 1.00 17.46 ? 111  PRO B CG  1 
ATOM   4621  C CD  . PRO B 1 132 ? 127.522 78.384  123.830 1.00 17.46 ? 111  PRO B CD  1 
ATOM   4622  N N   . ILE B 1 133 ? 125.932 79.067  128.289 1.00 17.22 ? 112  ILE B N   1 
ATOM   4623  C CA  . ILE B 1 133 ? 124.969 79.744  129.148 1.00 17.22 ? 112  ILE B CA  1 
ATOM   4624  C C   . ILE B 1 133 ? 125.219 81.243  129.158 1.00 17.22 ? 112  ILE B C   1 
ATOM   4625  O O   . ILE B 1 133 ? 124.290 82.037  129.358 1.00 17.22 ? 112  ILE B O   1 
ATOM   4626  C CB  . ILE B 1 133 ? 125.018 79.146  130.567 1.00 17.22 ? 112  ILE B CB  1 
ATOM   4627  C CG1 . ILE B 1 133 ? 123.899 79.716  131.434 1.00 17.22 ? 112  ILE B CG1 1 
ATOM   4628  C CG2 . ILE B 1 133 ? 126.373 79.385  131.204 1.00 17.22 ? 112  ILE B CG2 1 
ATOM   4629  C CD1 . ILE B 1 133 ? 122.533 79.519  130.853 1.00 17.22 ? 112  ILE B CD1 1 
ATOM   4630  N N   . ARG B 1 134 ? 126.465 81.662  128.938 1.00 20.51 ? 113  ARG B N   1 
ATOM   4631  C CA  . ARG B 1 134 ? 126.748 83.089  128.893 1.00 20.51 ? 113  ARG B CA  1 
ATOM   4632  C C   . ARG B 1 134 ? 126.114 83.736  127.672 1.00 20.51 ? 113  ARG B C   1 
ATOM   4633  O O   . ARG B 1 134 ? 125.664 84.883  127.743 1.00 20.51 ? 113  ARG B O   1 
ATOM   4634  C CB  . ARG B 1 134 ? 128.258 83.334  128.918 1.00 20.51 ? 113  ARG B CB  1 
ATOM   4635  C CG  . ARG B 1 134 ? 128.980 83.002  127.624 1.00 20.51 ? 113  ARG B CG  1 
ATOM   4636  C CD  . ARG B 1 134 ? 130.482 83.146  127.770 1.00 20.51 ? 113  ARG B CD  1 
ATOM   4637  N NE  . ARG B 1 134 ? 131.113 83.458  126.493 1.00 20.51 ? 113  ARG B NE  1 
ATOM   4638  C CZ  . ARG B 1 134 ? 131.814 84.561  126.262 1.00 20.51 ? 113  ARG B CZ  1 
ATOM   4639  N NH1 . ARG B 1 134 ? 131.979 85.455  127.224 1.00 20.51 ? 113  ARG B NH1 1 
ATOM   4640  N NH2 . ARG B 1 134 ? 132.353 84.770  125.070 1.00 20.51 ? 113  ARG B NH2 1 
ATOM   4641  N N   . GLU B 1 135 ? 126.037 83.010  126.558 1.00 17.29 ? 114  GLU B N   1 
ATOM   4642  C CA  . GLU B 1 135 ? 125.446 83.557  125.348 1.00 17.29 ? 114  GLU B CA  1 
ATOM   4643  C C   . GLU B 1 135 ? 123.928 83.578  125.400 1.00 17.29 ? 114  GLU B C   1 
ATOM   4644  O O   . GLU B 1 135 ? 123.306 84.281  124.600 1.00 17.29 ? 114  GLU B O   1 
ATOM   4645  C CB  . GLU B 1 135 ? 125.911 82.760  124.132 1.00 17.29 ? 114  GLU B CB  1 
ATOM   4646  C CG  . GLU B 1 135 ? 126.131 83.602  122.898 1.00 17.29 ? 114  GLU B CG  1 
ATOM   4647  C CD  . GLU B 1 135 ? 126.440 82.768  121.672 1.00 17.29 ? 114  GLU B CD  1 
ATOM   4648  O OE1 . GLU B 1 135 ? 126.042 83.180  120.562 1.00 17.29 ? 114  GLU B OE1 1 
ATOM   4649  O OE2 . GLU B 1 135 ? 127.080 81.706  121.819 1.00 17.29 ? 114  GLU B OE2 1 
ATOM   4650  N N   . THR B 1 136 ? 123.318 82.825  126.314 1.00 14.85 ? 115  THR B N   1 
ATOM   4651  C CA  . THR B 1 136 ? 121.878 82.901  126.512 1.00 14.85 ? 115  THR B CA  1 
ATOM   4652  C C   . THR B 1 136 ? 121.484 83.891  127.597 1.00 14.85 ? 115  THR B C   1 
ATOM   4653  O O   . THR B 1 136 ? 120.422 84.511  127.496 1.00 14.85 ? 115  THR B O   1 
ATOM   4654  C CB  . THR B 1 136 ? 121.310 81.523  126.855 1.00 14.85 ? 115  THR B CB  1 
ATOM   4655  O OG1 . THR B 1 136 ? 121.594 81.215  128.223 1.00 14.85 ? 115  THR B OG1 1 
ATOM   4656  C CG2 . THR B 1 136 ? 121.923 80.469  125.971 1.00 14.85 ? 115  THR B CG2 1 
ATOM   4657  N N   . MET B 1 137 ? 122.303 84.060  128.633 1.00 16.45 ? 116  MET B N   1 
ATOM   4658  C CA  . MET B 1 137 ? 122.024 85.101  129.613 1.00 16.45 ? 116  MET B CA  1 
ATOM   4659  C C   . MET B 1 137 ? 122.533 86.472  129.191 1.00 16.45 ? 116  MET B C   1 
ATOM   4660  O O   . MET B 1 137 ? 122.181 87.466  129.834 1.00 16.45 ? 116  MET B O   1 
ATOM   4661  C CB  . MET B 1 137 ? 122.618 84.735  130.975 1.00 16.45 ? 116  MET B CB  1 
ATOM   4662  C CG  . MET B 1 137 ? 121.959 83.548  131.643 1.00 16.45 ? 116  MET B CG  1 
ATOM   4663  S SD  . MET B 1 137 ? 122.704 83.161  133.234 1.00 16.45 ? 116  MET B SD  1 
ATOM   4664  C CE  . MET B 1 137 ? 121.783 81.697  133.690 1.00 16.45 ? 116  MET B CE  1 
ATOM   4665  N N   . ALA B 1 138 ? 123.341 86.556  128.136 1.00 14.88 ? 117  ALA B N   1 
ATOM   4666  C CA  . ALA B 1 138 ? 123.861 87.833  127.667 1.00 14.88 ? 117  ALA B CA  1 
ATOM   4667  C C   . ALA B 1 138 ? 123.149 88.311  126.407 1.00 14.88 ? 117  ALA B C   1 
ATOM   4668  O O   . ALA B 1 138 ? 122.627 89.428  126.372 1.00 14.88 ? 117  ALA B O   1 
ATOM   4669  C CB  . ALA B 1 138 ? 125.370 87.725  127.418 1.00 14.88 ? 117  ALA B CB  1 
ATOM   4670  N N   . ALA B 1 139 ? 123.118 87.481  125.366 1.00 14.63 ? 118  ALA B N   1 
ATOM   4671  C CA  . ALA B 1 139 ? 122.553 87.891  124.086 1.00 14.63 ? 118  ALA B CA  1 
ATOM   4672  C C   . ALA B 1 139 ? 121.093 87.471  123.934 1.00 14.63 ? 118  ALA B C   1 
ATOM   4673  O O   . ALA B 1 139 ? 120.211 88.321  123.791 1.00 14.63 ? 118  ALA B O   1 
ATOM   4674  C CB  . ALA B 1 139 ? 123.391 87.319  122.938 1.00 14.63 ? 118  ALA B CB  1 
ATOM   4675  N N   . ASP B 1 140 ? 120.826 86.167  123.993 1.00 12.84 ? 119  ASP B N   1 
ATOM   4676  C CA  . ASP B 1 140 ? 119.549 85.637  123.526 1.00 12.84 ? 119  ASP B CA  1 
ATOM   4677  C C   . ASP B 1 140 ? 118.370 86.214  124.301 1.00 12.84 ? 119  ASP B C   1 
ATOM   4678  O O   . ASP B 1 140 ? 117.515 86.899  123.732 1.00 12.84 ? 119  ASP B O   1 
ATOM   4679  C CB  . ASP B 1 140 ? 119.566 84.114  123.612 1.00 12.84 ? 119  ASP B CB  1 
ATOM   4680  C CG  . ASP B 1 140 ? 120.057 83.470  122.335 1.00 12.84 ? 119  ASP B CG  1 
ATOM   4681  O OD1 . ASP B 1 140 ? 119.621 83.900  121.248 1.00 12.84 ? 119  ASP B OD1 1 
ATOM   4682  O OD2 . ASP B 1 140 ? 120.892 82.549  122.413 1.00 12.84 ? 119  ASP B OD2 1 
ATOM   4683  N N   . LEU B 1 141 ? 118.294 85.933  125.597 1.00 9.93  ? 120  LEU B N   1 
ATOM   4684  C CA  . LEU B 1 141 ? 117.135 86.372  126.374 1.00 9.93  ? 120  LEU B CA  1 
ATOM   4685  C C   . LEU B 1 141 ? 116.983 87.885  126.446 1.00 9.93  ? 120  LEU B C   1 
ATOM   4686  O O   . LEU B 1 141 ? 115.847 88.374  126.300 1.00 9.93  ? 120  LEU B O   1 
ATOM   4687  C CB  . LEU B 1 141 ? 117.177 85.745  127.770 1.00 9.93  ? 120  LEU B CB  1 
ATOM   4688  C CG  . LEU B 1 141 ? 116.537 84.368  127.908 1.00 9.93  ? 120  LEU B CG  1 
ATOM   4689  C CD1 . LEU B 1 141 ? 115.060 84.522  127.635 1.00 9.93  ? 120  LEU B CD1 1 
ATOM   4690  C CD2 . LEU B 1 141 ? 117.144 83.349  126.976 1.00 9.93  ? 120  LEU B CD2 1 
ATOM   4691  N N   . PRO B 1 142 ? 118.030 88.676  126.708 1.00 8.57  ? 121  PRO B N   1 
ATOM   4692  C CA  . PRO B 1 142 ? 117.846 90.131  126.629 1.00 8.57  ? 121  PRO B CA  1 
ATOM   4693  C C   . PRO B 1 142 ? 117.380 90.599  125.264 1.00 8.57  ? 121  PRO B C   1 
ATOM   4694  O O   . PRO B 1 142 ? 116.548 91.507  125.189 1.00 8.57  ? 121  PRO B O   1 
ATOM   4695  C CB  . PRO B 1 142 ? 119.235 90.669  126.988 1.00 8.57  ? 121  PRO B CB  1 
ATOM   4696  C CG  . PRO B 1 142 ? 119.794 89.634  127.871 1.00 8.57  ? 121  PRO B CG  1 
ATOM   4697  C CD  . PRO B 1 142 ? 119.349 88.339  127.273 1.00 8.57  ? 121  PRO B CD  1 
ATOM   4698  N N   . LEU B 1 143 ? 117.863 89.989  124.180 1.00 7.00  ? 122  LEU B N   1 
ATOM   4699  C CA  . LEU B 1 143 ? 117.392 90.375  122.854 1.00 7.00  ? 122  LEU B CA  1 
ATOM   4700  C C   . LEU B 1 143 ? 115.916 90.043  122.665 1.00 7.00  ? 122  LEU B C   1 
ATOM   4701  O O   . LEU B 1 143 ? 115.172 90.832  122.075 1.00 7.00  ? 122  LEU B O   1 
ATOM   4702  C CB  . LEU B 1 143 ? 118.232 89.701  121.774 1.00 7.00  ? 122  LEU B CB  1 
ATOM   4703  C CG  . LEU B 1 143 ? 119.581 90.339  121.448 1.00 7.00  ? 122  LEU B CG  1 
ATOM   4704  C CD1 . LEU B 1 143 ? 120.298 89.551  120.377 1.00 7.00  ? 122  LEU B CD1 1 
ATOM   4705  C CD2 . LEU B 1 143 ? 119.400 91.776  121.023 1.00 7.00  ? 122  LEU B CD2 1 
ATOM   4706  N N   . ALA B 1 144 ? 115.473 88.881  123.146 1.00 5.71  ? 123  ALA B N   1 
ATOM   4707  C CA  . ALA B 1 144 ? 114.066 88.513  123.008 1.00 5.71  ? 123  ALA B CA  1 
ATOM   4708  C C   . ALA B 1 144 ? 113.165 89.451  123.801 1.00 5.71  ? 123  ALA B C   1 
ATOM   4709  O O   . ALA B 1 144 ? 112.118 89.896  123.303 1.00 5.71  ? 123  ALA B O   1 
ATOM   4710  C CB  . ALA B 1 144 ? 113.860 87.069  123.454 1.00 5.71  ? 123  ALA B CB  1 
ATOM   4711  N N   . ILE B 1 145 ? 113.552 89.764  125.037 1.00 5.56  ? 124  ILE B N   1 
ATOM   4712  C CA  . ILE B 1 145 ? 112.771 90.705  125.835 1.00 5.56  ? 124  ILE B CA  1 
ATOM   4713  C C   . ILE B 1 145 ? 112.765 92.076  125.175 1.00 5.56  ? 124  ILE B C   1 
ATOM   4714  O O   . ILE B 1 145 ? 111.741 92.774  125.152 1.00 5.56  ? 124  ILE B O   1 
ATOM   4715  C CB  . ILE B 1 145 ? 113.323 90.765  127.269 1.00 5.56  ? 124  ILE B CB  1 
ATOM   4716  C CG1 . ILE B 1 145 ? 113.091 89.441  127.984 1.00 5.56  ? 124  ILE B CG1 1 
ATOM   4717  C CG2 . ILE B 1 145 ? 112.674 91.874  128.041 1.00 5.56  ? 124  ILE B CG2 1 
ATOM   4718  C CD1 . ILE B 1 145 ? 114.167 89.109  128.978 1.00 5.56  ? 124  ILE B CD1 1 
ATOM   4719  N N   . ASP B 1 146 ? 113.904 92.472  124.604 1.00 5.72  ? 125  ASP B N   1 
ATOM   4720  C CA  . ASP B 1 146 ? 113.996 93.754  123.923 1.00 5.72  ? 125  ASP B CA  1 
ATOM   4721  C C   . ASP B 1 146 ? 113.092 93.797  122.704 1.00 5.72  ? 125  ASP B C   1 
ATOM   4722  O O   . ASP B 1 146 ? 112.514 94.839  122.401 1.00 5.72  ? 125  ASP B O   1 
ATOM   4723  C CB  . ASP B 1 146 ? 115.442 94.029  123.524 1.00 5.72  ? 125  ASP B CB  1 
ATOM   4724  C CG  . ASP B 1 146 ? 115.730 95.501  123.381 1.00 5.72  ? 125  ASP B CG  1 
ATOM   4725  O OD1 . ASP B 1 146 ? 114.899 96.311  123.843 1.00 5.72  ? 125  ASP B OD1 1 
ATOM   4726  O OD2 . ASP B 1 146 ? 116.782 95.850  122.807 1.00 5.72  ? 125  ASP B OD2 1 
ATOM   4727  N N   . HIS B 1 147 ? 112.975 92.685  121.982 1.00 4.53  ? 126  HIS B N   1 
ATOM   4728  C CA  . HIS B 1 147 ? 112.069 92.639  120.838 1.00 4.53  ? 126  HIS B CA  1 
ATOM   4729  C C   . HIS B 1 147 ? 110.620 92.758  121.269 1.00 4.53  ? 126  HIS B C   1 
ATOM   4730  O O   . HIS B 1 147 ? 109.834 93.470  120.633 1.00 4.53  ? 126  HIS B O   1 
ATOM   4731  C CB  . HIS B 1 147 ? 112.276 91.353  120.052 1.00 4.53  ? 126  HIS B CB  1 
ATOM   4732  C CG  . HIS B 1 147 ? 113.166 91.520  118.869 1.00 4.53  ? 126  HIS B CG  1 
ATOM   4733  N ND1 . HIS B 1 147 ? 112.706 91.985  117.658 1.00 4.53  ? 126  HIS B ND1 1 
ATOM   4734  C CD2 . HIS B 1 147 ? 114.493 91.313  118.715 1.00 4.53  ? 126  HIS B CD2 1 
ATOM   4735  C CE1 . HIS B 1 147 ? 113.710 92.044  116.804 1.00 4.53  ? 126  HIS B CE1 1 
ATOM   4736  N NE2 . HIS B 1 147 ? 114.806 91.644  117.421 1.00 4.53  ? 126  HIS B NE2 1 
ATOM   4737  N N   . PHE B 1 148 ? 110.237 92.055  122.331 1.00 4.38  ? 127  PHE B N   1 
ATOM   4738  C CA  . PHE B 1 148 ? 108.853 92.170  122.771 1.00 4.38  ? 127  PHE B CA  1 
ATOM   4739  C C   . PHE B 1 148 ? 108.530 93.556  123.308 1.00 4.38  ? 127  PHE B C   1 
ATOM   4740  O O   . PHE B 1 148 ? 107.372 93.973  123.242 1.00 4.38  ? 127  PHE B O   1 
ATOM   4741  C CB  . PHE B 1 148 ? 108.524 91.099  123.808 1.00 4.38  ? 127  PHE B CB  1 
ATOM   4742  C CG  . PHE B 1 148 ? 107.969 89.846  123.207 1.00 4.38  ? 127  PHE B CG  1 
ATOM   4743  C CD1 . PHE B 1 148 ? 106.627 89.751  122.899 1.00 4.38  ? 127  PHE B CD1 1 
ATOM   4744  C CD2 . PHE B 1 148 ? 108.791 88.777  122.920 1.00 4.38  ? 127  PHE B CD2 1 
ATOM   4745  C CE1 . PHE B 1 148 ? 106.114 88.610  122.332 1.00 4.38  ? 127  PHE B CE1 1 
ATOM   4746  C CE2 . PHE B 1 148 ? 108.281 87.637  122.354 1.00 4.38  ? 127  PHE B CE2 1 
ATOM   4747  C CZ  . PHE B 1 148 ? 106.942 87.553  122.061 1.00 4.38  ? 127  PHE B CZ  1 
ATOM   4748  N N   . ARG B 1 149 ? 109.516 94.278  123.836 1.00 3.21  ? 128  ARG B N   1 
ATOM   4749  C CA  . ARG B 1 149 ? 109.290 95.673  124.199 1.00 3.21  ? 128  ARG B CA  1 
ATOM   4750  C C   . ARG B 1 149 ? 109.291 96.598  122.985 1.00 3.21  ? 128  ARG B C   1 
ATOM   4751  O O   . ARG B 1 149 ? 108.463 97.513  122.893 1.00 3.21  ? 128  ARG B O   1 
ATOM   4752  C CB  . ARG B 1 149 ? 110.351 96.130  125.197 1.00 3.21  ? 128  ARG B CB  1 
ATOM   4753  C CG  . ARG B 1 149 ? 110.408 95.295  126.448 1.00 3.21  ? 128  ARG B CG  1 
ATOM   4754  C CD  . ARG B 1 149 ? 110.734 96.147  127.638 1.00 3.21  ? 128  ARG B CD  1 
ATOM   4755  N NE  . ARG B 1 149 ? 110.444 95.487  128.904 1.00 3.21  ? 128  ARG B NE  1 
ATOM   4756  C CZ  . ARG B 1 149 ? 111.362 94.893  129.655 1.00 3.21  ? 128  ARG B CZ  1 
ATOM   4757  N NH1 . ARG B 1 149 ? 112.627 94.873  129.265 1.00 3.21  ? 128  ARG B NH1 1 
ATOM   4758  N NH2 . ARG B 1 149 ? 111.014 94.326  130.798 1.00 3.21  ? 128  ARG B NH2 1 
ATOM   4759  N N   . TYR B 1 150 ? 110.202 96.362  122.043 1.00 3.18  ? 129  TYR B N   1 
ATOM   4760  C CA  . TYR B 1 150 ? 110.337 97.219  120.875 1.00 3.18  ? 129  TYR B CA  1 
ATOM   4761  C C   . TYR B 1 150 ? 109.092 97.179  120.007 1.00 3.18  ? 129  TYR B C   1 
ATOM   4762  O O   . TYR B 1 150 ? 108.547 98.222  119.636 1.00 3.18  ? 129  TYR B O   1 
ATOM   4763  C CB  . TYR B 1 150 ? 111.551 96.790  120.062 1.00 3.18  ? 129  TYR B CB  1 
ATOM   4764  C CG  . TYR B 1 150 ? 111.684 97.534  118.769 1.00 3.18  ? 129  TYR B CG  1 
ATOM   4765  C CD1 . TYR B 1 150 ? 112.036 98.866  118.757 1.00 3.18  ? 129  TYR B CD1 1 
ATOM   4766  C CD2 . TYR B 1 150 ? 111.435 96.911  117.560 1.00 3.18  ? 129  TYR B CD2 1 
ATOM   4767  C CE1 . TYR B 1 150 ? 112.152 99.551  117.584 1.00 3.18  ? 129  TYR B CE1 1 
ATOM   4768  C CE2 . TYR B 1 150 ? 111.545 97.595  116.378 1.00 3.18  ? 129  TYR B CE2 1 
ATOM   4769  C CZ  . TYR B 1 150 ? 111.913 98.914  116.396 1.00 3.18  ? 129  TYR B CZ  1 
ATOM   4770  O OH  . TYR B 1 150 ? 112.027 99.613  115.222 1.00 3.18  ? 129  TYR B OH  1 
ATOM   4771  N N   . PHE B 1 151 ? 108.629 95.980  119.660 1.00 2.65  ? 130  PHE B N   1 
ATOM   4772  C CA  . PHE B 1 151 ? 107.473 95.886  118.784 1.00 2.65  ? 130  PHE B CA  1 
ATOM   4773  C C   . PHE B 1 151 ? 106.180 96.213  119.509 1.00 2.65  ? 130  PHE B C   1 
ATOM   4774  O O   . PHE B 1 151 ? 105.166 96.458  118.855 1.00 2.65  ? 130  PHE B O   1 
ATOM   4775  C CB  . PHE B 1 151 ? 107.411 94.502  118.155 1.00 2.65  ? 130  PHE B CB  1 
ATOM   4776  C CG  . PHE B 1 151 ? 108.285 94.363  116.957 1.00 2.65  ? 130  PHE B CG  1 
ATOM   4777  C CD1 . PHE B 1 151 ? 107.997 95.050  115.798 1.00 2.65  ? 130  PHE B CD1 1 
ATOM   4778  C CD2 . PHE B 1 151 ? 109.409 93.568  116.996 1.00 2.65  ? 130  PHE B CD2 1 
ATOM   4779  C CE1 . PHE B 1 151 ? 108.801 94.931  114.696 1.00 2.65  ? 130  PHE B CE1 1 
ATOM   4780  C CE2 . PHE B 1 151 ? 110.220 93.448  115.899 1.00 2.65  ? 130  PHE B CE2 1 
ATOM   4781  C CZ  . PHE B 1 151 ? 109.916 94.129  114.744 1.00 2.65  ? 130  PHE B CZ  1 
ATOM   4782  N N   . ALA B 1 152 ? 106.190 96.223  120.839 1.00 3.32  ? 131  ALA B N   1 
ATOM   4783  C CA  . ALA B 1 152 ? 105.101 96.843  121.574 1.00 3.32  ? 131  ALA B CA  1 
ATOM   4784  C C   . ALA B 1 152 ? 105.208 98.357  121.568 1.00 3.32  ? 131  ALA B C   1 
ATOM   4785  O O   . ALA B 1 152 ? 104.214 99.038  121.831 1.00 3.32  ? 131  ALA B O   1 
ATOM   4786  C CB  . ALA B 1 152 ? 105.069 96.338  123.014 1.00 3.32  ? 131  ALA B CB  1 
ATOM   4787  N N   . GLY B 1 153 ? 106.391 98.891  121.290 1.00 3.41  ? 132  GLY B N   1 
ATOM   4788  C CA  . GLY B 1 153 ? 106.544 100.320 121.126 1.00 3.41  ? 132  GLY B CA  1 
ATOM   4789  C C   . GLY B 1 153 ? 106.185 100.792 119.734 1.00 3.41  ? 132  GLY B C   1 
ATOM   4790  O O   . GLY B 1 153 ? 105.421 101.744 119.569 1.00 3.41  ? 132  GLY B O   1 
ATOM   4791  N N   . VAL B 1 154 ? 106.743 100.126 118.724 1.00 2.93  ? 133  VAL B N   1 
ATOM   4792  C CA  . VAL B 1 154 ? 106.436 100.433 117.329 1.00 2.93  ? 133  VAL B CA  1 
ATOM   4793  C C   . VAL B 1 154 ? 104.943 100.359 117.050 1.00 2.93  ? 133  VAL B C   1 
ATOM   4794  O O   . VAL B 1 154 ? 104.417 101.115 116.226 1.00 2.93  ? 133  VAL B O   1 
ATOM   4795  C CB  . VAL B 1 154 ? 107.227 99.484  116.415 1.00 2.93  ? 133  VAL B CB  1 
ATOM   4796  C CG1 . VAL B 1 154 ? 106.641 99.475  115.030 1.00 2.93  ? 133  VAL B CG1 1 
ATOM   4797  C CG2 . VAL B 1 154 ? 108.674 99.905  116.369 1.00 2.93  ? 133  VAL B CG2 1 
ATOM   4798  N N   . LEU B 1 155 ? 104.231 99.470  117.736 1.00 3.11  ? 134  LEU B N   1 
ATOM   4799  C CA  . LEU B 1 155 ? 102.797 99.349  117.518 1.00 3.11  ? 134  LEU B CA  1 
ATOM   4800  C C   . LEU B 1 155 ? 102.023 100.518 118.112 1.00 3.11  ? 134  LEU B C   1 
ATOM   4801  O O   . LEU B 1 155 ? 100.971 100.890 117.582 1.00 3.11  ? 134  LEU B O   1 
ATOM   4802  C CB  . LEU B 1 155 ? 102.295 98.032  118.101 1.00 3.11  ? 134  LEU B CB  1 
ATOM   4803  C CG  . LEU B 1 155 ? 100.789 97.810  118.074 1.00 3.11  ? 134  LEU B CG  1 
ATOM   4804  C CD1 . LEU B 1 155 ? 100.320 97.590  116.648 1.00 3.11  ? 134  LEU B CD1 1 
ATOM   4805  C CD2 . LEU B 1 155 ? 100.421 96.641  118.964 1.00 3.11  ? 134  LEU B CD2 1 
ATOM   4806  N N   . ARG B 1 156 ? 102.514 101.114 119.199 1.00 4.44  ? 135  ARG B N   1 
ATOM   4807  C CA  . ARG B 1 156 ? 101.808 102.250 119.780 1.00 4.44  ? 135  ARG B CA  1 
ATOM   4808  C C   . ARG B 1 156 ? 101.936 103.494 118.916 1.00 4.44  ? 135  ARG B C   1 
ATOM   4809  O O   . ARG B 1 156 ? 101.014 104.312 118.871 1.00 4.44  ? 135  ARG B O   1 
ATOM   4810  C CB  . ARG B 1 156 ? 102.323 102.534 121.187 1.00 4.44  ? 135  ARG B CB  1 
ATOM   4811  C CG  . ARG B 1 156 ? 101.923 101.489 122.204 1.00 4.44  ? 135  ARG B CG  1 
ATOM   4812  C CD  . ARG B 1 156 ? 101.259 102.115 123.404 1.00 4.44  ? 135  ARG B CD  1 
ATOM   4813  N NE  . ARG B 1 156 ? 100.120 102.938 123.019 1.00 4.44  ? 135  ARG B NE  1 
ATOM   4814  C CZ  . ARG B 1 156 ? 99.401  103.658 123.873 1.00 4.44  ? 135  ARG B CZ  1 
ATOM   4815  N NH1 . ARG B 1 156 ? 99.706  103.653 125.161 1.00 4.44  ? 135  ARG B NH1 1 
ATOM   4816  N NH2 . ARG B 1 156 ? 98.379  104.382 123.442 1.00 4.44  ? 135  ARG B NH2 1 
ATOM   4817  N N   . ALA B 1 157 ? 103.059 103.649 118.223 1.00 4.05  ? 136  ALA B N   1 
ATOM   4818  C CA  . ALA B 1 157 ? 103.313 104.821 117.402 1.00 4.05  ? 136  ALA B CA  1 
ATOM   4819  C C   . ALA B 1 157 ? 102.880 104.640 115.955 1.00 4.05  ? 136  ALA B C   1 
ATOM   4820  O O   . ALA B 1 157 ? 102.990 105.586 115.170 1.00 4.05  ? 136  ALA B O   1 
ATOM   4821  C CB  . ALA B 1 157 ? 104.799 105.182 117.452 1.00 4.05  ? 136  ALA B CB  1 
ATOM   4822  N N   . GLN B 1 158 ? 102.392 103.463 115.584 1.00 2.56  ? 137  GLN B N   1 
ATOM   4823  C CA  . GLN B 1 158 ? 101.960 103.235 114.216 1.00 2.56  ? 137  GLN B CA  1 
ATOM   4824  C C   . GLN B 1 158 ? 100.736 104.079 113.892 1.00 2.56  ? 137  GLN B C   1 
ATOM   4825  O O   . GLN B 1 158 ? 99.889  104.341 114.749 1.00 2.56  ? 137  GLN B O   1 
ATOM   4826  C CB  . GLN B 1 158 ? 101.646 101.762 113.991 1.00 2.56  ? 137  GLN B CB  1 
ATOM   4827  C CG  . GLN B 1 158 ? 101.861 101.309 112.567 1.00 2.56  ? 137  GLN B CG  1 
ATOM   4828  C CD  . GLN B 1 158 ? 101.078 100.069 112.242 1.00 2.56  ? 137  GLN B CD  1 
ATOM   4829  O OE1 . GLN B 1 158 ? 100.067 99.781  112.877 1.00 2.56  ? 137  GLN B OE1 1 
ATOM   4830  N NE2 . GLN B 1 158 ? 101.539 99.321  111.252 1.00 2.56  ? 137  GLN B NE2 1 
ATOM   4831  N N   . GLU B 1 159 ? 100.648 104.500 112.634 1.00 3.42  ? 138  GLU B N   1 
ATOM   4832  C CA  . GLU B 1 159 ? 99.585  105.389 112.199 1.00 3.42  ? 138  GLU B CA  1 
ATOM   4833  C C   . GLU B 1 159 ? 99.345  105.204 110.713 1.00 3.42  ? 138  GLU B C   1 
ATOM   4834  O O   . GLU B 1 159 ? 100.294 105.157 109.929 1.00 3.42  ? 138  GLU B O   1 
ATOM   4835  C CB  . GLU B 1 159 ? 99.936  106.852 112.480 1.00 3.42  ? 138  GLU B CB  1 
ATOM   4836  C CG  . GLU B 1 159 ? 99.465  107.365 113.825 1.00 3.42  ? 138  GLU B CG  1 
ATOM   4837  C CD  . GLU B 1 159 ? 99.954  108.765 114.108 1.00 3.42  ? 138  GLU B CD  1 
ATOM   4838  O OE1 . GLU B 1 159 ? 99.166  109.715 113.936 1.00 3.42  ? 138  GLU B OE1 1 
ATOM   4839  O OE2 . GLU B 1 159 ? 101.130 108.918 114.497 1.00 3.42  ? 138  GLU B OE2 1 
ATOM   4840  N N   . GLY B 1 160 ? 98.080  105.111 110.331 1.00 2.55  ? 139  GLY B N   1 
ATOM   4841  C CA  . GLY B 1 160 ? 97.728  105.128 108.932 1.00 2.55  ? 139  GLY B CA  1 
ATOM   4842  C C   . GLY B 1 160 ? 97.896  106.519 108.360 1.00 2.55  ? 139  GLY B C   1 
ATOM   4843  O O   . GLY B 1 160 ? 98.058  107.509 109.071 1.00 2.55  ? 139  GLY B O   1 
ATOM   4844  N N   . SER B 1 161 ? 97.857  106.595 107.039 1.00 2.31  ? 140  SER B N   1 
ATOM   4845  C CA  . SER B 1 161 ? 98.057  107.851 106.339 1.00 2.31  ? 140  SER B CA  1 
ATOM   4846  C C   . SER B 1 161 ? 96.762  108.298 105.681 1.00 2.31  ? 140  SER B C   1 
ATOM   4847  O O   . SER B 1 161 ? 95.933  107.481 105.281 1.00 2.31  ? 140  SER B O   1 
ATOM   4848  C CB  . SER B 1 161 ? 99.155  107.733 105.292 1.00 2.31  ? 140  SER B CB  1 
ATOM   4849  O OG  . SER B 1 161 ? 98.903  106.655 104.420 1.00 2.31  ? 140  SER B OG  1 
ATOM   4850  N N   . ILE B 1 162 ? 96.602  109.610 105.569 1.00 2.40  ? 141  ILE B N   1 
ATOM   4851  C CA  . ILE B 1 162 ? 95.389  110.224 105.050 1.00 2.40  ? 141  ILE B CA  1 
ATOM   4852  C C   . ILE B 1 162 ? 95.833  111.202 103.966 1.00 2.40  ? 141  ILE B C   1 
ATOM   4853  O O   . ILE B 1 162 ? 96.449  112.231 104.251 1.00 2.40  ? 141  ILE B O   1 
ATOM   4854  C CB  . ILE B 1 162 ? 94.557  110.889 106.160 1.00 2.40  ? 141  ILE B CB  1 
ATOM   4855  C CG1 . ILE B 1 162 ? 93.197  111.329 105.689 1.00 2.40  ? 141  ILE B CG1 1 
ATOM   4856  C CG2 . ILE B 1 162 ? 95.211  112.050 106.821 1.00 2.40  ? 141  ILE B CG2 1 
ATOM   4857  C CD1 . ILE B 1 162 ? 92.370  111.680 106.872 1.00 2.40  ? 141  ILE B CD1 1 
ATOM   4858  N N   . SER B 1 163 ? 95.590  110.847 102.712 1.00 3.00  ? 142  SER B N   1 
ATOM   4859  C CA  . SER B 1 163 ? 96.166  111.564 101.577 1.00 3.00  ? 142  SER B CA  1 
ATOM   4860  C C   . SER B 1 163 ? 95.088  112.432 100.943 1.00 3.00  ? 142  SER B C   1 
ATOM   4861  O O   . SER B 1 163 ? 94.285  111.966 100.141 1.00 3.00  ? 142  SER B O   1 
ATOM   4862  C CB  . SER B 1 163 ? 96.755  110.588 100.572 1.00 3.00  ? 142  SER B CB  1 
ATOM   4863  O OG  . SER B 1 163 ? 95.774  110.141 99.661  1.00 3.00  ? 142  SER B OG  1 
ATOM   4864  N N   . GLN B 1 164 ? 95.074  113.709 101.316 1.00 3.12  ? 143  GLN B N   1 
ATOM   4865  C CA  . GLN B 1 164 ? 94.171  114.673 100.703 1.00 3.12  ? 143  GLN B CA  1 
ATOM   4866  C C   . GLN B 1 164 ? 94.394  114.707 99.198  1.00 3.12  ? 143  GLN B C   1 
ATOM   4867  O O   . GLN B 1 164 ? 95.522  114.877 98.731  1.00 3.12  ? 143  GLN B O   1 
ATOM   4868  C CB  . GLN B 1 164 ? 94.423  116.055 101.307 1.00 3.12  ? 143  GLN B CB  1 
ATOM   4869  C CG  . GLN B 1 164 ? 93.479  117.147 100.857 1.00 3.12  ? 143  GLN B CG  1 
ATOM   4870  C CD  . GLN B 1 164 ? 92.219  117.209 101.683 1.00 3.12  ? 143  GLN B CD  1 
ATOM   4871  O OE1 . GLN B 1 164 ? 92.044  116.439 102.622 1.00 3.12  ? 143  GLN B OE1 1 
ATOM   4872  N NE2 . GLN B 1 164 ? 91.333  118.128 101.340 1.00 3.12  ? 143  GLN B NE2 1 
ATOM   4873  N N   . ILE B 1 165 ? 93.317  114.535 98.435  1.00 2.31  ? 144  ILE B N   1 
ATOM   4874  C CA  . ILE B 1 165 ? 93.406  114.530 96.985  1.00 2.31  ? 144  ILE B CA  1 
ATOM   4875  C C   . ILE B 1 165 ? 92.851  115.809 96.370  1.00 2.31  ? 144  ILE B C   1 
ATOM   4876  O O   . ILE B 1 165 ? 93.398  116.290 95.372  1.00 2.31  ? 144  ILE B O   1 
ATOM   4877  C CB  . ILE B 1 165 ? 92.698  113.291 96.398  1.00 2.31  ? 144  ILE B CB  1 
ATOM   4878  C CG1 . ILE B 1 165 ? 93.197  112.013 97.071  1.00 2.31  ? 144  ILE B CG1 1 
ATOM   4879  C CG2 . ILE B 1 165 ? 92.914  113.208 94.898  1.00 2.31  ? 144  ILE B CG2 1 
ATOM   4880  C CD1 . ILE B 1 165 ? 94.557  111.566 96.612  1.00 2.31  ? 144  ILE B CD1 1 
ATOM   4881  N N   . ASP B 1 166 ? 91.784  116.355 96.923  1.00 2.92  ? 145  ASP B N   1 
ATOM   4882  C CA  . ASP B 1 166 ? 91.239  117.671 96.615  1.00 2.92  ? 145  ASP B CA  1 
ATOM   4883  C C   . ASP B 1 166 ? 90.244  117.973 97.727  1.00 2.92  ? 145  ASP B C   1 
ATOM   4884  O O   . ASP B 1 166 ? 90.175  117.241 98.722  1.00 2.92  ? 145  ASP B O   1 
ATOM   4885  C CB  . ASP B 1 166 ? 90.625  117.719 95.217  1.00 2.92  ? 145  ASP B CB  1 
ATOM   4886  C CG  . ASP B 1 166 ? 89.661  116.588 94.962  1.00 2.92  ? 145  ASP B CG  1 
ATOM   4887  O OD1 . ASP B 1 166 ? 88.655  116.490 95.689  1.00 2.92  ? 145  ASP B OD1 1 
ATOM   4888  O OD2 . ASP B 1 166 ? 89.904  115.799 94.025  1.00 2.92  ? 145  ASP B OD2 1 
ATOM   4889  N N   . ASP B 1 167 ? 89.470  119.046 97.581  1.00 5.81  ? 146  ASP B N   1 
ATOM   4890  C CA  . ASP B 1 167 ? 88.495  119.359 98.618  1.00 5.81  ? 146  ASP B CA  1 
ATOM   4891  C C   . ASP B 1 167 ? 87.371  118.339 98.689  1.00 5.81  ? 146  ASP B C   1 
ATOM   4892  O O   . ASP B 1 167 ? 86.655  118.294 99.693  1.00 5.81  ? 146  ASP B O   1 
ATOM   4893  C CB  . ASP B 1 167 ? 87.893  120.739 98.395  1.00 5.81  ? 146  ASP B CB  1 
ATOM   4894  C CG  . ASP B 1 167 ? 88.881  121.840 98.625  1.00 5.81  ? 146  ASP B CG  1 
ATOM   4895  O OD1 . ASP B 1 167 ? 89.807  121.659 99.443  1.00 5.81  ? 146  ASP B OD1 1 
ATOM   4896  O OD2 . ASP B 1 167 ? 88.718  122.897 97.991  1.00 5.81  ? 146  ASP B OD2 1 
ATOM   4897  N N   . ASP B 1 168 ? 87.200  117.524 97.650  1.00 4.98  ? 147  ASP B N   1 
ATOM   4898  C CA  . ASP B 1 168 ? 86.082  116.602 97.572  1.00 4.98  ? 147  ASP B CA  1 
ATOM   4899  C C   . ASP B 1 168 ? 86.458  115.151 97.805  1.00 4.98  ? 147  ASP B C   1 
ATOM   4900  O O   . ASP B 1 168 ? 85.580  114.356 98.144  1.00 4.98  ? 147  ASP B O   1 
ATOM   4901  C CB  . ASP B 1 168 ? 85.403  116.721 96.202  1.00 4.98  ? 147  ASP B CB  1 
ATOM   4902  C CG  . ASP B 1 168 ? 85.123  118.152 95.825  1.00 4.98  ? 147  ASP B CG  1 
ATOM   4903  O OD1 . ASP B 1 168 ? 84.643  118.909 96.693  1.00 4.98  ? 147  ASP B OD1 1 
ATOM   4904  O OD2 . ASP B 1 168 ? 85.388  118.526 94.667  1.00 4.98  ? 147  ASP B OD2 1 
ATOM   4905  N N   . THR B 1 169 ? 87.727  114.790 97.650  1.00 3.24  ? 148  THR B N   1 
ATOM   4906  C CA  . THR B 1 169 ? 88.154  113.401 97.700  1.00 3.24  ? 148  THR B CA  1 
ATOM   4907  C C   . THR B 1 169 ? 89.293  113.246 98.691  1.00 3.24  ? 148  THR B C   1 
ATOM   4908  O O   . THR B 1 169 ? 90.261  114.008 98.648  1.00 3.24  ? 148  THR B O   1 
ATOM   4909  C CB  . THR B 1 169 ? 88.592  112.930 96.319  1.00 3.24  ? 148  THR B CB  1 
ATOM   4910  O OG1 . THR B 1 169 ? 87.660  113.410 95.345  1.00 3.24  ? 148  THR B OG1 1 
ATOM   4911  C CG2 . THR B 1 169 ? 88.632  111.422 96.262  1.00 3.24  ? 148  THR B CG2 1 
ATOM   4912  N N   . VAL B 1 170 ? 89.179  112.265 99.582  1.00 3.90  ? 149  VAL B N   1 
ATOM   4913  C CA  . VAL B 1 170 ? 90.235  111.944 100.535 1.00 3.90  ? 149  VAL B CA  1 
ATOM   4914  C C   . VAL B 1 170 ? 90.436  110.437 100.552 1.00 3.90  ? 149  VAL B C   1 
ATOM   4915  O O   . VAL B 1 170 ? 89.465  109.680 100.616 1.00 3.90  ? 149  VAL B O   1 
ATOM   4916  C CB  . VAL B 1 170 ? 89.914  112.450 101.953 1.00 3.90  ? 149  VAL B CB  1 
ATOM   4917  C CG1 . VAL B 1 170 ? 91.087  112.197 102.866 1.00 3.90  ? 149  VAL B CG1 1 
ATOM   4918  C CG2 . VAL B 1 170 ? 89.577  113.920 101.936 1.00 3.90  ? 149  VAL B CG2 1 
ATOM   4919  N N   . ALA B 1 171 ? 91.691  110.006 100.513 1.00 2.69  ? 150  ALA B N   1 
ATOM   4920  C CA  . ALA B 1 171 ? 92.045  108.598 100.629 1.00 2.69  ? 150  ALA B CA  1 
ATOM   4921  C C   . ALA B 1 171 ? 92.564  108.328 102.035 1.00 2.69  ? 150  ALA B C   1 
ATOM   4922  O O   . ALA B 1 171 ? 93.548  108.933 102.462 1.00 2.69  ? 150  ALA B O   1 
ATOM   4923  C CB  . ALA B 1 171 ? 93.092  108.213 99.588  1.00 2.69  ? 150  ALA B CB  1 
ATOM   4924  N N   . TYR B 1 172 ? 91.904  107.424 102.750 1.00 10.72 ? 151  TYR B N   1 
ATOM   4925  C CA  . TYR B 1 172 ? 92.306  107.011 104.084 1.00 10.72 ? 151  TYR B CA  1 
ATOM   4926  C C   . TYR B 1 172 ? 92.937  105.632 104.008 1.00 10.72 ? 151  TYR B C   1 
ATOM   4927  O O   . TYR B 1 172 ? 92.312  104.690 103.522 1.00 10.72 ? 151  TYR B O   1 
ATOM   4928  C CB  . TYR B 1 172 ? 91.111  106.970 105.034 1.00 10.72 ? 151  TYR B CB  1 
ATOM   4929  C CG  . TYR B 1 172 ? 90.210  108.171 104.963 1.00 10.72 ? 151  TYR B CG  1 
ATOM   4930  C CD1 . TYR B 1 172 ? 89.225  108.268 104.000 1.00 10.72 ? 151  TYR B CD1 1 
ATOM   4931  C CD2 . TYR B 1 172 ? 90.322  109.194 105.881 1.00 10.72 ? 151  TYR B CD2 1 
ATOM   4932  C CE1 . TYR B 1 172 ? 88.402  109.363 103.940 1.00 10.72 ? 151  TYR B CE1 1 
ATOM   4933  C CE2 . TYR B 1 172 ? 89.495  110.291 105.830 1.00 10.72 ? 151  TYR B CE2 1 
ATOM   4934  C CZ  . TYR B 1 172 ? 88.541  110.369 104.859 1.00 10.72 ? 151  TYR B CZ  1 
ATOM   4935  O OH  . TYR B 1 172 ? 87.716  111.460 104.804 1.00 10.72 ? 151  TYR B OH  1 
ATOM   4936  N N   . HIS B 1 173 ? 94.160  105.506 104.500 1.00 3.42  ? 152  HIS B N   1 
ATOM   4937  C CA  . HIS B 1 173 ? 94.846  104.225 104.546 1.00 3.42  ? 152  HIS B CA  1 
ATOM   4938  C C   . HIS B 1 173 ? 94.867  103.716 105.977 1.00 3.42  ? 152  HIS B C   1 
ATOM   4939  O O   . HIS B 1 173 ? 95.289  104.428 106.891 1.00 3.42  ? 152  HIS B O   1 
ATOM   4940  C CB  . HIS B 1 173 ? 96.260  104.346 103.989 1.00 3.42  ? 152  HIS B CB  1 
ATOM   4941  C CG  . HIS B 1 173 ? 96.310  104.979 102.638 1.00 3.42  ? 152  HIS B CG  1 
ATOM   4942  N ND1 . HIS B 1 173 ? 96.154  106.332 102.443 1.00 3.42  ? 152  HIS B ND1 1 
ATOM   4943  C CD2 . HIS B 1 173 ? 96.480  104.441 101.410 1.00 3.42  ? 152  HIS B CD2 1 
ATOM   4944  C CE1 . HIS B 1 173 ? 96.237  106.602 101.155 1.00 3.42  ? 152  HIS B CE1 1 
ATOM   4945  N NE2 . HIS B 1 173 ? 96.434  105.471 100.506 1.00 3.42  ? 152  HIS B NE2 1 
ATOM   4946  N N   . PHE B 1 174 ? 94.400  102.493 106.165 1.00 3.42  ? 153  PHE B N   1 
ATOM   4947  C CA  . PHE B 1 174 ? 94.344  101.850 107.462 1.00 3.42  ? 153  PHE B CA  1 
ATOM   4948  C C   . PHE B 1 174 ? 95.217  100.607 107.438 1.00 3.42  ? 153  PHE B C   1 
ATOM   4949  O O   . PHE B 1 174 ? 95.402  99.987  106.390 1.00 3.42  ? 153  PHE B O   1 
ATOM   4950  C CB  . PHE B 1 174 ? 92.916  101.450 107.822 1.00 3.42  ? 153  PHE B CB  1 
ATOM   4951  C CG  . PHE B 1 174 ? 91.969  102.603 107.968 1.00 3.42  ? 153  PHE B CG  1 
ATOM   4952  C CD1 . PHE B 1 174 ? 91.861  103.278 109.167 1.00 3.42  ? 153  PHE B CD1 1 
ATOM   4953  C CD2 . PHE B 1 174 ? 91.163  102.990 106.920 1.00 3.42  ? 153  PHE B CD2 1 
ATOM   4954  C CE1 . PHE B 1 174 ? 90.987  104.326 109.310 1.00 3.42  ? 153  PHE B CE1 1 
ATOM   4955  C CE2 . PHE B 1 174 ? 90.289  104.040 107.062 1.00 3.42  ? 153  PHE B CE2 1 
ATOM   4956  C CZ  . PHE B 1 174 ? 90.202  104.707 108.260 1.00 3.42  ? 153  PHE B CZ  1 
ATOM   4957  N N   . HIS B 1 175 ? 95.736  100.237 108.602 1.00 2.94  ? 154  HIS B N   1 
ATOM   4958  C CA  . HIS B 1 175 ? 96.471  98.992  108.771 1.00 2.94  ? 154  HIS B CA  1 
ATOM   4959  C C   . HIS B 1 175 ? 95.559  97.961  109.419 1.00 2.94  ? 154  HIS B C   1 
ATOM   4960  O O   . HIS B 1 175 ? 94.915  98.247  110.433 1.00 2.94  ? 154  HIS B O   1 
ATOM   4961  C CB  . HIS B 1 175 ? 97.713  99.194  109.635 1.00 2.94  ? 154  HIS B CB  1 
ATOM   4962  C CG  . HIS B 1 175 ? 98.701  100.166 109.074 1.00 2.94  ? 154  HIS B CG  1 
ATOM   4963  N ND1 . HIS B 1 175 ? 99.441  99.908  107.942 1.00 2.94  ? 154  HIS B ND1 1 
ATOM   4964  C CD2 . HIS B 1 175 ? 99.095  101.384 109.512 1.00 2.94  ? 154  HIS B CD2 1 
ATOM   4965  C CE1 . HIS B 1 175 ? 100.236 100.932 107.697 1.00 2.94  ? 154  HIS B CE1 1 
ATOM   4966  N NE2 . HIS B 1 175 ? 100.046 101.841 108.636 1.00 2.94  ? 154  HIS B NE2 1 
ATOM   4967  N N   . GLU B 1 176 ? 95.515  96.766  108.845 1.00 5.08  ? 155  GLU B N   1 
ATOM   4968  C CA  . GLU B 1 176 ? 94.712  95.677  109.368 1.00 5.08  ? 155  GLU B CA  1 
ATOM   4969  C C   . GLU B 1 176 ? 95.566  94.428  109.501 1.00 5.08  ? 155  GLU B C   1 
ATOM   4970  O O   . GLU B 1 176 ? 96.549  94.264  108.776 1.00 5.08  ? 155  GLU B O   1 
ATOM   4971  C CB  . GLU B 1 176 ? 93.519  95.375  108.452 1.00 5.08  ? 155  GLU B CB  1 
ATOM   4972  C CG  . GLU B 1 176 ? 92.720  96.587  108.044 1.00 5.08  ? 155  GLU B CG  1 
ATOM   4973  C CD  . GLU B 1 176 ? 91.291  96.237  107.706 1.00 5.08  ? 155  GLU B CD  1 
ATOM   4974  O OE1 . GLU B 1 176 ? 90.807  96.672  106.644 1.00 5.08  ? 155  GLU B OE1 1 
ATOM   4975  O OE2 . GLU B 1 176 ? 90.650  95.519  108.499 1.00 5.08  ? 155  GLU B OE2 1 
ATOM   4976  N N   . PRO B 1 177 ? 95.216  93.535  110.421 1.00 2.12  ? 156  PRO B N   1 
ATOM   4977  C CA  . PRO B 1 177 ? 95.947  92.272  110.535 1.00 2.12  ? 156  PRO B CA  1 
ATOM   4978  C C   . PRO B 1 177 ? 95.786  91.412  109.291 1.00 2.12  ? 156  PRO B C   1 
ATOM   4979  O O   . PRO B 1 177 ? 94.769  91.465  108.598 1.00 2.12  ? 156  PRO B O   1 
ATOM   4980  C CB  . PRO B 1 177 ? 95.306  91.607  111.754 1.00 2.12  ? 156  PRO B CB  1 
ATOM   4981  C CG  . PRO B 1 177 ? 94.722  92.714  112.524 1.00 2.12  ? 156  PRO B CG  1 
ATOM   4982  C CD  . PRO B 1 177 ? 94.276  93.728  111.534 1.00 2.12  ? 156  PRO B CD  1 
ATOM   4983  N N   . LEU B 1 178 ? 96.812  90.607  109.014 1.00 3.45  ? 157  LEU B N   1 
ATOM   4984  C CA  . LEU B 1 178 ? 96.740  89.655  107.914 1.00 3.45  ? 157  LEU B CA  1 
ATOM   4985  C C   . LEU B 1 178 ? 95.761  88.522  108.182 1.00 3.45  ? 157  LEU B C   1 
ATOM   4986  O O   . LEU B 1 178 ? 95.300  87.883  107.232 1.00 3.45  ? 157  LEU B O   1 
ATOM   4987  C CB  . LEU B 1 178 ? 98.116  89.060  107.634 1.00 3.45  ? 157  LEU B CB  1 
ATOM   4988  C CG  . LEU B 1 178 ? 99.061  89.828  106.723 1.00 3.45  ? 157  LEU B CG  1 
ATOM   4989  C CD1 . LEU B 1 178 ? 100.334 89.047  106.554 1.00 3.45  ? 157  LEU B CD1 1 
ATOM   4990  C CD2 . LEU B 1 178 ? 98.415  90.063  105.391 1.00 3.45  ? 157  LEU B CD2 1 
ATOM   4991  N N   . GLY B 1 179 ? 95.433  88.256  109.442 1.00 3.74  ? 158  GLY B N   1 
ATOM   4992  C CA  . GLY B 1 179 ? 94.592  87.124  109.770 1.00 3.74  ? 158  GLY B CA  1 
ATOM   4993  C C   . GLY B 1 179 ? 95.304  86.097  110.622 1.00 3.74  ? 158  GLY B C   1 
ATOM   4994  O O   . GLY B 1 179 ? 95.571  86.343  111.799 1.00 3.74  ? 158  GLY B O   1 
ATOM   4995  N N   . VAL B 1 180 ? 95.603  84.937  110.049 1.00 5.03  ? 159  VAL B N   1 
ATOM   4996  C CA  . VAL B 1 180 ? 96.344  83.884  110.731 1.00 5.03  ? 159  VAL B CA  1 
ATOM   4997  C C   . VAL B 1 180 ? 97.613  83.620  109.935 1.00 5.03  ? 159  VAL B C   1 
ATOM   4998  O O   . VAL B 1 180 ? 97.550  83.343  108.732 1.00 5.03  ? 159  VAL B O   1 
ATOM   4999  C CB  . VAL B 1 180 ? 95.511  82.601  110.884 1.00 5.03  ? 159  VAL B CB  1 
ATOM   5000  C CG1 . VAL B 1 180 ? 96.387  81.449  111.335 1.00 5.03  ? 159  VAL B CG1 1 
ATOM   5001  C CG2 . VAL B 1 180 ? 94.388  82.818  111.870 1.00 5.03  ? 159  VAL B CG2 1 
ATOM   5002  N N   . VAL B 1 181 ? 98.758  83.706  110.604 1.00 6.17  ? 160  VAL B N   1 
ATOM   5003  C CA  . VAL B 1 181 ? 100.061 83.531  109.978 1.00 6.17  ? 160  VAL B CA  1 
ATOM   5004  C C   . VAL B 1 181 ? 100.674 82.232  110.481 1.00 6.17  ? 160  VAL B C   1 
ATOM   5005  O O   . VAL B 1 181 ? 100.475 81.844  111.636 1.00 6.17  ? 160  VAL B O   1 
ATOM   5006  C CB  . VAL B 1 181 ? 100.980 84.737  110.262 1.00 6.17  ? 160  VAL B CB  1 
ATOM   5007  C CG1 . VAL B 1 181 ? 101.461 84.735  111.698 1.00 6.17  ? 160  VAL B CG1 1 
ATOM   5008  C CG2 . VAL B 1 181 ? 102.157 84.757  109.307 1.00 6.17  ? 160  VAL B CG2 1 
ATOM   5009  N N   . GLY B 1 182 ? 101.397 81.547  109.603 1.00 8.15  ? 161  GLY B N   1 
ATOM   5010  C CA  . GLY B 1 182 ? 102.089 80.335  109.983 1.00 8.15  ? 161  GLY B CA  1 
ATOM   5011  C C   . GLY B 1 182 ? 103.585 80.537  109.941 1.00 8.15  ? 161  GLY B C   1 
ATOM   5012  O O   . GLY B 1 182 ? 104.107 81.095  108.975 1.00 8.15  ? 161  GLY B O   1 
ATOM   5013  N N   . GLN B 1 183 ? 104.285 80.092  110.979 1.00 7.59  ? 162  GLN B N   1 
ATOM   5014  C CA  . GLN B 1 183 ? 105.692 80.408  111.169 1.00 7.59  ? 162  GLN B CA  1 
ATOM   5015  C C   . GLN B 1 183 ? 106.476 79.124  111.383 1.00 7.59  ? 162  GLN B C   1 
ATOM   5016  O O   . GLN B 1 183 ? 106.064 78.271  112.174 1.00 7.59  ? 162  GLN B O   1 
ATOM   5017  C CB  . GLN B 1 183 ? 105.854 81.344  112.362 1.00 7.59  ? 162  GLN B CB  1 
ATOM   5018  C CG  . GLN B 1 183 ? 105.243 82.706  112.130 1.00 7.59  ? 162  GLN B CG  1 
ATOM   5019  C CD  . GLN B 1 183 ? 105.382 83.620  113.320 1.00 7.59  ? 162  GLN B CD  1 
ATOM   5020  O OE1 . GLN B 1 183 ? 105.883 83.221  114.366 1.00 7.59  ? 162  GLN B OE1 1 
ATOM   5021  N NE2 . GLN B 1 183 ? 104.936 84.857  113.168 1.00 7.59  ? 162  GLN B NE2 1 
ATOM   5022  N N   . ILE B 1 184 ? 107.598 78.987  110.687 1.00 9.63  ? 163  ILE B N   1 
ATOM   5023  C CA  . ILE B 1 184 ? 108.477 77.831  110.811 1.00 9.63  ? 163  ILE B CA  1 
ATOM   5024  C C   . ILE B 1 184 ? 109.840 78.356  111.239 1.00 9.63  ? 163  ILE B C   1 
ATOM   5025  O O   . ILE B 1 184 ? 110.657 78.745  110.397 1.00 9.63  ? 163  ILE B O   1 
ATOM   5026  C CB  . ILE B 1 184 ? 108.575 77.032  109.509 1.00 9.63  ? 163  ILE B CB  1 
ATOM   5027  C CG1 . ILE B 1 184 ? 107.188 76.578  109.054 1.00 9.63  ? 163  ILE B CG1 1 
ATOM   5028  C CG2 . ILE B 1 184 ? 109.498 75.835  109.685 1.00 9.63  ? 163  ILE B CG2 1 
ATOM   5029  C CD1 . ILE B 1 184 ? 107.132 76.192  107.597 1.00 9.63  ? 163  ILE B CD1 1 
ATOM   5030  N N   . ILE B 1 185 ? 110.094 78.363  112.543 1.00 9.21  ? 164  ILE B N   1 
ATOM   5031  C CA  . ILE B 1 185 ? 111.327 78.913  113.100 1.00 9.21  ? 164  ILE B CA  1 
ATOM   5032  C C   . ILE B 1 185 ? 112.448 77.885  112.991 1.00 9.21  ? 164  ILE B C   1 
ATOM   5033  O O   . ILE B 1 185 ? 112.175 76.678  112.964 1.00 9.21  ? 164  ILE B O   1 
ATOM   5034  C CB  . ILE B 1 185 ? 111.113 79.358  114.552 1.00 9.21  ? 164  ILE B CB  1 
ATOM   5035  C CG1 . ILE B 1 185 ? 110.554 78.203  115.373 1.00 9.21  ? 164  ILE B CG1 1 
ATOM   5036  C CG2 . ILE B 1 185 ? 110.166 80.537  114.596 1.00 9.21  ? 164  ILE B CG2 1 
ATOM   5037  C CD1 . ILE B 1 185 ? 110.122 78.588  116.752 1.00 9.21  ? 164  ILE B CD1 1 
ATOM   5038  N N   . PRO B 1 186 ? 113.706 78.306  112.913 1.00 11.54 ? 165  PRO B N   1 
ATOM   5039  C CA  . PRO B 1 186 ? 114.815 77.357  112.819 1.00 11.54 ? 165  PRO B CA  1 
ATOM   5040  C C   . PRO B 1 186 ? 115.375 77.001  114.192 1.00 11.54 ? 165  PRO B C   1 
ATOM   5041  O O   . PRO B 1 186 ? 114.995 77.566  115.218 1.00 11.54 ? 165  PRO B O   1 
ATOM   5042  C CB  . PRO B 1 186 ? 115.841 78.130  111.990 1.00 11.54 ? 165  PRO B CB  1 
ATOM   5043  C CG  . PRO B 1 186 ? 115.638 79.543  112.422 1.00 11.54 ? 165  PRO B CG  1 
ATOM   5044  C CD  . PRO B 1 186 ? 114.190 79.694  112.850 1.00 11.54 ? 165  PRO B CD  1 
ATOM   5045  N N   . TRP B 1 187 ? 116.304 76.046  114.186 1.00 13.09 ? 166  TRP B N   1 
ATOM   5046  C CA  . TRP B 1 187 ? 116.805 75.489  115.437 1.00 13.09 ? 166  TRP B CA  1 
ATOM   5047  C C   . TRP B 1 187 ? 117.871 76.366  116.080 1.00 13.09 ? 166  TRP B C   1 
ATOM   5048  O O   . TRP B 1 187 ? 117.859 76.559  117.300 1.00 13.09 ? 166  TRP B O   1 
ATOM   5049  C CB  . TRP B 1 187 ? 117.353 74.083  115.200 1.00 13.09 ? 166  TRP B CB  1 
ATOM   5050  C CG  . TRP B 1 187 ? 118.094 73.942  113.913 1.00 13.09 ? 166  TRP B CG  1 
ATOM   5051  C CD1 . TRP B 1 187 ? 117.566 73.640  112.696 1.00 13.09 ? 166  TRP B CD1 1 
ATOM   5052  C CD2 . TRP B 1 187 ? 119.501 74.099  113.711 1.00 13.09 ? 166  TRP B CD2 1 
ATOM   5053  N NE1 . TRP B 1 187 ? 118.556 73.598  111.748 1.00 13.09 ? 166  TRP B NE1 1 
ATOM   5054  C CE2 . TRP B 1 187 ? 119.754 73.876  112.348 1.00 13.09 ? 166  TRP B CE2 1 
ATOM   5055  C CE3 . TRP B 1 187 ? 120.572 74.404  114.552 1.00 13.09 ? 166  TRP B CE3 1 
ATOM   5056  C CZ2 . TRP B 1 187 ? 121.031 73.953  111.807 1.00 13.09 ? 166  TRP B CZ2 1 
ATOM   5057  C CZ3 . TRP B 1 187 ? 121.836 74.480  114.013 1.00 13.09 ? 166  TRP B CZ3 1 
ATOM   5058  C CH2 . TRP B 1 187 ? 122.056 74.257  112.657 1.00 13.09 ? 166  TRP B CH2 1 
ATOM   5059  N N   . ASN B 1 188 ? 118.789 76.917  115.281 1.00 14.19 ? 167  ASN B N   1 
ATOM   5060  C CA  . ASN B 1 188 ? 119.990 77.540  115.829 1.00 14.19 ? 167  ASN B CA  1 
ATOM   5061  C C   . ASN B 1 188 ? 119.692 78.700  116.770 1.00 14.19 ? 167  ASN B C   1 
ATOM   5062  O O   . ASN B 1 188 ? 120.533 79.024  117.614 1.00 14.19 ? 167  ASN B O   1 
ATOM   5063  C CB  . ASN B 1 188 ? 120.901 78.002  114.694 1.00 14.19 ? 167  ASN B CB  1 
ATOM   5064  C CG  . ASN B 1 188 ? 120.175 78.827  113.660 1.00 14.19 ? 167  ASN B CG  1 
ATOM   5065  O OD1 . ASN B 1 188 ? 118.974 79.052  113.761 1.00 14.19 ? 167  ASN B OD1 1 
ATOM   5066  N ND2 . ASN B 1 188 ? 120.906 79.286  112.655 1.00 14.19 ? 167  ASN B ND2 1 
ATOM   5067  N N   . PHE B 1 189 ? 118.529 79.332  116.651 1.00 12.32 ? 168  PHE B N   1 
ATOM   5068  C CA  . PHE B 1 189 ? 118.069 80.316  117.629 1.00 12.32 ? 168  PHE B CA  1 
ATOM   5069  C C   . PHE B 1 189 ? 116.652 79.931  118.023 1.00 12.32 ? 168  PHE B C   1 
ATOM   5070  O O   . PHE B 1 189 ? 115.676 80.390  117.415 1.00 12.32 ? 168  PHE B O   1 
ATOM   5071  C CB  . PHE B 1 189 ? 118.149 81.734  117.077 1.00 12.32 ? 168  PHE B CB  1 
ATOM   5072  C CG  . PHE B 1 189 ? 119.539 82.290  117.057 1.00 12.32 ? 168  PHE B CG  1 
ATOM   5073  C CD1 . PHE B 1 189 ? 120.109 82.797  118.207 1.00 12.32 ? 168  PHE B CD1 1 
ATOM   5074  C CD2 . PHE B 1 189 ? 120.285 82.284  115.893 1.00 12.32 ? 168  PHE B CD2 1 
ATOM   5075  C CE1 . PHE B 1 189 ? 121.386 83.299  118.197 1.00 12.32 ? 168  PHE B CE1 1 
ATOM   5076  C CE2 . PHE B 1 189 ? 121.566 82.783  115.879 1.00 12.32 ? 168  PHE B CE2 1 
ATOM   5077  C CZ  . PHE B 1 189 ? 122.117 83.292  117.035 1.00 12.32 ? 168  PHE B CZ  1 
ATOM   5078  N N   . PRO B 1 190 ? 116.503 79.075  119.035 1.00 11.87 ? 169  PRO B N   1 
ATOM   5079  C CA  . PRO B 1 190 ? 115.173 78.535  119.347 1.00 11.87 ? 169  PRO B CA  1 
ATOM   5080  C C   . PRO B 1 190 ? 114.227 79.576  119.897 1.00 11.87 ? 169  PRO B C   1 
ATOM   5081  O O   . PRO B 1 190 ? 113.030 79.540  119.588 1.00 11.87 ? 169  PRO B O   1 
ATOM   5082  C CB  . PRO B 1 190 ? 115.473 77.455  120.396 1.00 11.87 ? 169  PRO B CB  1 
ATOM   5083  C CG  . PRO B 1 190 ? 116.972 77.280  120.370 1.00 11.87 ? 169  PRO B CG  1 
ATOM   5084  C CD  . PRO B 1 190 ? 117.520 78.594  119.977 1.00 11.87 ? 169  PRO B CD  1 
ATOM   5085  N N   . LEU B 1 191 ? 114.730 80.499  120.710 1.00 10.83 ? 170  LEU B N   1 
ATOM   5086  C CA  . LEU B 1 191 ? 113.902 81.484  121.377 1.00 10.83 ? 170  LEU B CA  1 
ATOM   5087  C C   . LEU B 1 191 ? 114.100 82.891  120.845 1.00 10.83 ? 170  LEU B C   1 
ATOM   5088  O O   . LEU B 1 191 ? 113.306 83.776  121.177 1.00 10.83 ? 170  LEU B O   1 
ATOM   5089  C CB  . LEU B 1 191 ? 114.180 81.470  122.883 1.00 10.83 ? 170  LEU B CB  1 
ATOM   5090  C CG  . LEU B 1 191 ? 113.010 81.915  123.748 1.00 10.83 ? 170  LEU B CG  1 
ATOM   5091  C CD1 . LEU B 1 191 ? 111.865 80.942  123.577 1.00 10.83 ? 170  LEU B CD1 1 
ATOM   5092  C CD2 . LEU B 1 191 ? 113.442 82.007  125.194 1.00 10.83 ? 170  LEU B CD2 1 
ATOM   5093  N N   . LEU B 1 192 ? 115.136 83.128  120.045 1.00 9.15  ? 171  LEU B N   1 
ATOM   5094  C CA  . LEU B 1 192 ? 115.315 84.434  119.431 1.00 9.15  ? 171  LEU B CA  1 
ATOM   5095  C C   . LEU B 1 192 ? 114.549 84.537  118.120 1.00 9.15  ? 171  LEU B C   1 
ATOM   5096  O O   . LEU B 1 192 ? 113.724 85.438  117.954 1.00 9.15  ? 171  LEU B O   1 
ATOM   5097  C CB  . LEU B 1 192 ? 116.801 84.716  119.210 1.00 9.15  ? 171  LEU B CB  1 
ATOM   5098  C CG  . LEU B 1 192 ? 117.185 86.193  119.188 1.00 9.15  ? 171  LEU B CG  1 
ATOM   5099  C CD1 . LEU B 1 192 ? 116.491 86.944  120.306 1.00 9.15  ? 171  LEU B CD1 1 
ATOM   5100  C CD2 . LEU B 1 192 ? 118.682 86.338  119.307 1.00 9.15  ? 171  LEU B CD2 1 
ATOM   5101  N N   . MET B 1 193 ? 114.797 83.614  117.189 1.00 10.33 ? 172  MET B N   1 
ATOM   5102  C CA  . MET B 1 193 ? 114.034 83.594  115.949 1.00 10.33 ? 172  MET B CA  1 
ATOM   5103  C C   . MET B 1 193 ? 112.558 83.327  116.192 1.00 10.33 ? 172  MET B C   1 
ATOM   5104  O O   . MET B 1 193 ? 111.733 83.655  115.335 1.00 10.33 ? 172  MET B O   1 
ATOM   5105  C CB  . MET B 1 193 ? 114.597 82.543  114.994 1.00 10.33 ? 172  MET B CB  1 
ATOM   5106  C CG  . MET B 1 193 ? 116.022 82.798  114.545 1.00 10.33 ? 172  MET B CG  1 
ATOM   5107  S SD  . MET B 1 193 ? 116.146 83.603  112.941 1.00 10.33 ? 172  MET B SD  1 
ATOM   5108  C CE  . MET B 1 193 ? 117.764 84.356  113.070 1.00 10.33 ? 172  MET B CE  1 
ATOM   5109  N N   . ALA B 1 194 ? 112.206 82.725  117.327 1.00 7.45  ? 173  ALA B N   1 
ATOM   5110  C CA  . ALA B 1 194 ? 110.798 82.595  117.673 1.00 7.45  ? 173  ALA B CA  1 
ATOM   5111  C C   . ALA B 1 194 ? 110.217 83.923  118.125 1.00 7.45  ? 173  ALA B C   1 
ATOM   5112  O O   . ALA B 1 194 ? 109.065 84.231  117.811 1.00 7.45  ? 173  ALA B O   1 
ATOM   5113  C CB  . ALA B 1 194 ? 110.611 81.545  118.764 1.00 7.45  ? 173  ALA B CB  1 
ATOM   5114  N N   . CYS B 1 195 ? 110.992 84.725  118.845 1.00 7.47  ? 174  CYS B N   1 
ATOM   5115  C CA  . CYS B 1 195 ? 110.530 86.028  119.293 1.00 7.47  ? 174  CYS B CA  1 
ATOM   5116  C C   . CYS B 1 195 ? 110.852 87.138  118.307 1.00 7.47  ? 174  CYS B C   1 
ATOM   5117  O O   . CYS B 1 195 ? 110.288 88.229  118.424 1.00 7.47  ? 174  CYS B O   1 
ATOM   5118  C CB  . CYS B 1 195 ? 111.129 86.356  120.660 1.00 7.47  ? 174  CYS B CB  1 
ATOM   5119  S SG  . CYS B 1 195 ? 110.646 85.194  121.956 1.00 7.47  ? 174  CYS B SG  1 
ATOM   5120  N N   . TRP B 1 196 ? 111.739 86.892  117.341 1.00 8.61  ? 175  TRP B N   1 
ATOM   5121  C CA  . TRP B 1 196 ? 111.923 87.838  116.251 1.00 8.61  ? 175  TRP B CA  1 
ATOM   5122  C C   . TRP B 1 196 ? 110.695 87.930  115.365 1.00 8.61  ? 175  TRP B C   1 
ATOM   5123  O O   . TRP B 1 196 ? 110.533 88.930  114.660 1.00 8.61  ? 175  TRP B O   1 
ATOM   5124  C CB  . TRP B 1 196 ? 113.120 87.450  115.385 1.00 8.61  ? 175  TRP B CB  1 
ATOM   5125  C CG  . TRP B 1 196 ? 114.423 88.037  115.813 1.00 8.61  ? 175  TRP B CG  1 
ATOM   5126  C CD1 . TRP B 1 196 ? 114.731 88.558  117.033 1.00 8.61  ? 175  TRP B CD1 1 
ATOM   5127  C CD2 . TRP B 1 196 ? 115.607 88.156  115.017 1.00 8.61  ? 175  TRP B CD2 1 
ATOM   5128  N NE1 . TRP B 1 196 ? 116.033 88.994  117.048 1.00 8.61  ? 175  TRP B NE1 1 
ATOM   5129  C CE2 . TRP B 1 196 ? 116.592 88.758  115.821 1.00 8.61  ? 175  TRP B CE2 1 
ATOM   5130  C CE3 . TRP B 1 196 ? 115.928 87.811  113.702 1.00 8.61  ? 175  TRP B CE3 1 
ATOM   5131  C CZ2 . TRP B 1 196 ? 117.872 89.025  115.353 1.00 8.61  ? 175  TRP B CZ2 1 
ATOM   5132  C CZ3 . TRP B 1 196 ? 117.200 88.076  113.241 1.00 8.61  ? 175  TRP B CZ3 1 
ATOM   5133  C CH2 . TRP B 1 196 ? 118.156 88.676  114.062 1.00 8.61  ? 175  TRP B CH2 1 
ATOM   5134  N N   . LYS B 1 197 ? 109.840 86.912  115.370 1.00 6.55  ? 176  LYS B N   1 
ATOM   5135  C CA  . LYS B 1 197 ? 108.722 86.837  114.444 1.00 6.55  ? 176  LYS B CA  1 
ATOM   5136  C C   . LYS B 1 197 ? 107.357 86.774  115.107 1.00 6.55  ? 176  LYS B C   1 
ATOM   5137  O O   . LYS B 1 197 ? 106.382 87.192  114.487 1.00 6.55  ? 176  LYS B O   1 
ATOM   5138  C CB  . LYS B 1 197 ? 108.887 85.624  113.523 1.00 6.55  ? 176  LYS B CB  1 
ATOM   5139  C CG  . LYS B 1 197 ? 110.000 85.808  112.523 1.00 6.55  ? 176  LYS B CG  1 
ATOM   5140  C CD  . LYS B 1 197 ? 110.343 84.523  111.813 1.00 6.55  ? 176  LYS B CD  1 
ATOM   5141  C CE  . LYS B 1 197 ? 111.343 84.789  110.701 1.00 6.55  ? 176  LYS B CE  1 
ATOM   5142  N NZ  . LYS B 1 197 ? 110.695 85.026  109.381 1.00 6.55  ? 176  LYS B NZ  1 
ATOM   5143  N N   . LEU B 1 198 ? 107.249 86.258  116.331 1.00 4.52  ? 177  LEU B N   1 
ATOM   5144  C CA  . LEU B 1 198 ? 105.988 86.364  117.058 1.00 4.52  ? 177  LEU B CA  1 
ATOM   5145  C C   . LEU B 1 198 ? 105.658 87.811  117.373 1.00 4.52  ? 177  LEU B C   1 
ATOM   5146  O O   . LEU B 1 198 ? 104.542 88.274  117.121 1.00 4.52  ? 177  LEU B O   1 
ATOM   5147  C CB  . LEU B 1 198 ? 106.031 85.547  118.346 1.00 4.52  ? 177  LEU B CB  1 
ATOM   5148  C CG  . LEU B 1 198 ? 106.034 84.041  118.188 1.00 4.52  ? 177  LEU B CG  1 
ATOM   5149  C CD1 . LEU B 1 198 ? 106.236 83.411  119.521 1.00 4.52  ? 177  LEU B CD1 1 
ATOM   5150  C CD2 . LEU B 1 198 ? 104.706 83.638  117.635 1.00 4.52  ? 177  LEU B CD2 1 
ATOM   5151  N N   . ALA B 1 199 ? 106.611 88.534  117.951 1.00 3.60  ? 178  ALA B N   1 
ATOM   5152  C CA  . ALA B 1 199 ? 106.362 89.916  118.352 1.00 3.60  ? 178  ALA B CA  1 
ATOM   5153  C C   . ALA B 1 199 ? 105.873 90.792  117.205 1.00 3.60  ? 178  ALA B C   1 
ATOM   5154  O O   . ALA B 1 199 ? 104.876 91.505  117.394 1.00 3.60  ? 178  ALA B O   1 
ATOM   5155  C CB  . ALA B 1 199 ? 107.628 90.478  119.010 1.00 3.60  ? 178  ALA B CB  1 
ATOM   5156  N N   . PRO B 1 200 ? 106.487 90.789  116.014 1.00 3.38  ? 179  PRO B N   1 
ATOM   5157  C CA  . PRO B 1 200 ? 105.859 91.503  114.891 1.00 3.38  ? 179  PRO B CA  1 
ATOM   5158  C C   . PRO B 1 200 ? 104.482 90.980  114.542 1.00 3.38  ? 179  PRO B C   1 
ATOM   5159  O O   . PRO B 1 200 ? 103.590 91.767  114.211 1.00 3.38  ? 179  PRO B O   1 
ATOM   5160  C CB  . PRO B 1 200 ? 106.844 91.281  113.737 1.00 3.38  ? 179  PRO B CB  1 
ATOM   5161  C CG  . PRO B 1 200 ? 108.110 90.997  114.368 1.00 3.38  ? 179  PRO B CG  1 
ATOM   5162  C CD  . PRO B 1 200 ? 107.816 90.283  115.644 1.00 3.38  ? 179  PRO B CD  1 
ATOM   5163  N N   . ALA B 1 201 ? 104.284 89.663  114.612 1.00 2.94  ? 180  ALA B N   1 
ATOM   5164  C CA  . ALA B 1 201 ? 103.023 89.067  114.190 1.00 2.94  ? 180  ALA B CA  1 
ATOM   5165  C C   . ALA B 1 201 ? 101.923 89.264  115.222 1.00 2.94  ? 180  ALA B C   1 
ATOM   5166  O O   . ALA B 1 201 ? 100.768 89.488  114.858 1.00 2.94  ? 180  ALA B O   1 
ATOM   5167  C CB  . ALA B 1 201 ? 103.221 87.583  113.898 1.00 2.94  ? 180  ALA B CB  1 
ATOM   5168  N N   . ILE B 1 202 ? 102.252 89.174  116.507 1.00 2.84  ? 181  ILE B N   1 
ATOM   5169  C CA  . ILE B 1 202 ? 101.245 89.383  117.541 1.00 2.84  ? 181  ILE B CA  1 
ATOM   5170  C C   . ILE B 1 202 ? 100.975 90.866  117.751 1.00 2.84  ? 181  ILE B C   1 
ATOM   5171  O O   . ILE B 1 202 ? 99.851  91.255  118.085 1.00 2.84  ? 181  ILE B O   1 
ATOM   5172  C CB  . ILE B 1 202 ? 101.681 88.689  118.842 1.00 2.84  ? 181  ILE B CB  1 
ATOM   5173  C CG1 . ILE B 1 202 ? 101.768 87.181  118.628 1.00 2.84  ? 181  ILE B CG1 1 
ATOM   5174  C CG2 . ILE B 1 202 ? 100.744 89.024  119.986 1.00 2.84  ? 181  ILE B CG2 1 
ATOM   5175  C CD1 . ILE B 1 202 ? 102.427 86.450  119.758 1.00 2.84  ? 181  ILE B CD1 1 
ATOM   5176  N N   . ALA B 1 203 ? 101.981 91.719  117.555 1.00 2.98  ? 182  ALA B N   1 
ATOM   5177  C CA  . ALA B 1 203 ? 101.743 93.154  117.587 1.00 2.98  ? 182  ALA B CA  1 
ATOM   5178  C C   . ALA B 1 203 ? 100.768 93.564  116.495 1.00 2.98  ? 182  ALA B C   1 
ATOM   5179  O O   . ALA B 1 203 ? 99.834  94.335  116.736 1.00 2.98  ? 182  ALA B O   1 
ATOM   5180  C CB  . ALA B 1 203 ? 103.066 93.902  117.437 1.00 2.98  ? 182  ALA B CB  1 
ATOM   5181  N N   . ALA B 1 204 ? 100.954 93.039  115.296 1.00 2.72  ? 183  ALA B N   1 
ATOM   5182  C CA  . ALA B 1 204 ? 100.088 93.372  114.179 1.00 2.72  ? 183  ALA B CA  1 
ATOM   5183  C C   . ALA B 1 204 ? 98.725  92.728  114.268 1.00 2.72  ? 183  ALA B C   1 
ATOM   5184  O O   . ALA B 1 204 ? 97.981  92.850  113.301 1.00 2.72  ? 183  ALA B O   1 
ATOM   5185  C CB  . ALA B 1 204 ? 100.762 92.978  112.869 1.00 2.72  ? 183  ALA B CB  1 
ATOM   5186  N N   . GLY B 1 205 ? 98.363  92.055  115.356 1.00 2.92  ? 184  GLY B N   1 
ATOM   5187  C CA  . GLY B 1 205 ? 97.018  91.552  115.542 1.00 2.92  ? 184  GLY B CA  1 
ATOM   5188  C C   . GLY B 1 205 ? 96.712  90.210  114.919 1.00 2.92  ? 184  GLY B C   1 
ATOM   5189  O O   . GLY B 1 205 ? 95.542  89.817  114.891 1.00 2.92  ? 184  GLY B O   1 
ATOM   5190  N N   . ASN B 1 206 ? 97.711  89.496  114.412 1.00 2.82  ? 185  ASN B N   1 
ATOM   5191  C CA  . ASN B 1 206 ? 97.462  88.187  113.835 1.00 2.82  ? 185  ASN B CA  1 
ATOM   5192  C C   . ASN B 1 206 ? 97.437  87.112  114.917 1.00 2.82  ? 185  ASN B C   1 
ATOM   5193  O O   . ASN B 1 206 ? 97.874  87.313  116.050 1.00 2.82  ? 185  ASN B O   1 
ATOM   5194  C CB  . ASN B 1 206 ? 98.524  87.842  112.798 1.00 2.82  ? 185  ASN B CB  1 
ATOM   5195  C CG  . ASN B 1 206 ? 98.891  89.012  111.944 1.00 2.82  ? 185  ASN B CG  1 
ATOM   5196  O OD1 . ASN B 1 206 ? 98.074  89.519  111.186 1.00 2.82  ? 185  ASN B OD1 1 
ATOM   5197  N ND2 . ASN B 1 206 ? 100.126 89.456  112.059 1.00 2.82  ? 185  ASN B ND2 1 
ATOM   5198  N N   . CYS B 1 207 ? 96.916  85.950  114.545 1.00 3.95  ? 186  CYS B N   1 
ATOM   5199  C CA  . CYS B 1 207 ? 96.972  84.756  115.370 1.00 3.95  ? 186  CYS B CA  1 
ATOM   5200  C C   . CYS B 1 207 ? 97.971  83.795  114.748 1.00 3.95  ? 186  CYS B C   1 
ATOM   5201  O O   . CYS B 1 207 ? 97.995  83.618  113.527 1.00 3.95  ? 186  CYS B O   1 
ATOM   5202  C CB  . CYS B 1 207 ? 95.599  84.105  115.492 1.00 3.95  ? 186  CYS B CB  1 
ATOM   5203  S SG  . CYS B 1 207 ? 94.484  84.992  116.588 1.00 3.95  ? 186  CYS B SG  1 
ATOM   5204  N N   . VAL B 1 208 ? 98.809  83.189  115.580 1.00 4.48  ? 187  VAL B N   1 
ATOM   5205  C CA  . VAL B 1 208 ? 100.005 82.509  115.107 1.00 4.48  ? 187  VAL B CA  1 
ATOM   5206  C C   . VAL B 1 208 ? 99.869  81.012  115.336 1.00 4.48  ? 187  VAL B C   1 
ATOM   5207  O O   . VAL B 1 208 ? 99.493  80.571  116.430 1.00 4.48  ? 187  VAL B O   1 
ATOM   5208  C CB  . VAL B 1 208 ? 101.270 83.045  115.795 1.00 4.48  ? 187  VAL B CB  1 
ATOM   5209  C CG1 . VAL B 1 208 ? 102.479 82.278  115.304 1.00 4.48  ? 187  VAL B CG1 1 
ATOM   5210  C CG2 . VAL B 1 208 ? 101.425 84.532  115.544 1.00 4.48  ? 187  VAL B CG2 1 
ATOM   5211  N N   . VAL B 1 209 ? 100.160 80.243  114.292 1.00 5.12  ? 188  VAL B N   1 
ATOM   5212  C CA  . VAL B 1 209 ? 100.449 78.820  114.383 1.00 5.12  ? 188  VAL B CA  1 
ATOM   5213  C C   . VAL B 1 209 ? 101.951 78.672  114.191 1.00 5.12  ? 188  VAL B C   1 
ATOM   5214  O O   . VAL B 1 209 ? 102.459 78.770  113.067 1.00 5.12  ? 188  VAL B O   1 
ATOM   5215  C CB  . VAL B 1 209 ? 99.673  78.005  113.342 1.00 5.12  ? 188  VAL B CB  1 
ATOM   5216  C CG1 . VAL B 1 209 ? 100.031 76.533  113.454 1.00 5.12  ? 188  VAL B CG1 1 
ATOM   5217  C CG2 . VAL B 1 209 ? 98.184  78.212  113.515 1.00 5.12  ? 188  VAL B CG2 1 
ATOM   5218  N N   . LEU B 1 210 ? 102.657 78.432  115.288 1.00 6.67  ? 189  LEU B N   1 
ATOM   5219  C CA  . LEU B 1 210 ? 104.108 78.342  115.315 1.00 6.67  ? 189  LEU B CA  1 
ATOM   5220  C C   . LEU B 1 210 ? 104.528 76.881  115.280 1.00 6.67  ? 189  LEU B C   1 
ATOM   5221  O O   . LEU B 1 210 ? 103.975 76.056  116.011 1.00 6.67  ? 189  LEU B O   1 
ATOM   5222  C CB  . LEU B 1 210 ? 104.647 79.020  116.572 1.00 6.67  ? 189  LEU B CB  1 
ATOM   5223  C CG  . LEU B 1 210 ? 106.152 79.185  116.731 1.00 6.67  ? 189  LEU B CG  1 
ATOM   5224  C CD1 . LEU B 1 210 ? 106.781 79.581  115.415 1.00 6.67  ? 189  LEU B CD1 1 
ATOM   5225  C CD2 . LEU B 1 210 ? 106.423 80.226  117.792 1.00 6.67  ? 189  LEU B CD2 1 
ATOM   5226  N N   . LYS B 1 211 ? 105.499 76.563  114.429 1.00 8.42  ? 190  LYS B N   1 
ATOM   5227  C CA  . LYS B 1 211 ? 106.025 75.203  114.316 1.00 8.42  ? 190  LYS B CA  1 
ATOM   5228  C C   . LYS B 1 211 ? 107.516 75.188  114.625 1.00 8.42  ? 190  LYS B C   1 
ATOM   5229  O O   . LYS B 1 211 ? 108.339 75.483  113.741 1.00 8.42  ? 190  LYS B O   1 
ATOM   5230  C CB  . LYS B 1 211 ? 105.760 74.640  112.923 1.00 8.42  ? 190  LYS B CB  1 
ATOM   5231  C CG  . LYS B 1 211 ? 106.071 73.168  112.789 1.00 8.42  ? 190  LYS B CG  1 
ATOM   5232  C CD  . LYS B 1 211 ? 107.342 72.959  112.000 1.00 8.42  ? 190  LYS B CD  1 
ATOM   5233  C CE  . LYS B 1 211 ? 107.873 71.556  112.165 1.00 8.42  ? 190  LYS B CE  1 
ATOM   5234  N NZ  . LYS B 1 211 ? 109.112 71.363  111.372 1.00 8.42  ? 190  LYS B NZ  1 
ATOM   5235  N N   . PRO B 1 212 ? 107.914 74.853  115.850 1.00 10.70 ? 191  PRO B N   1 
ATOM   5236  C CA  . PRO B 1 212 ? 109.340 74.826  116.181 1.00 10.70 ? 191  PRO B CA  1 
ATOM   5237  C C   . PRO B 1 212 ? 110.073 73.729  115.433 1.00 10.70 ? 191  PRO B C   1 
ATOM   5238  O O   . PRO B 1 212 ? 109.518 72.671  115.131 1.00 10.70 ? 191  PRO B O   1 
ATOM   5239  C CB  . PRO B 1 212 ? 109.349 74.558  117.689 1.00 10.70 ? 191  PRO B CB  1 
ATOM   5240  C CG  . PRO B 1 212 ? 107.978 74.855  118.146 1.00 10.70 ? 191  PRO B CG  1 
ATOM   5241  C CD  . PRO B 1 212 ? 107.087 74.511  117.012 1.00 10.70 ? 191  PRO B CD  1 
ATOM   5242  N N   . ALA B 1 213 ? 111.342 73.993  115.141 1.00 12.68 ? 192  ALA B N   1 
ATOM   5243  C CA  . ALA B 1 213 ? 112.180 72.982  114.516 1.00 12.68 ? 192  ALA B CA  1 
ATOM   5244  C C   . ALA B 1 213 ? 112.327 71.783  115.442 1.00 12.68 ? 192  ALA B C   1 
ATOM   5245  O O   . ALA B 1 213 ? 112.544 71.939  116.646 1.00 12.68 ? 192  ALA B O   1 
ATOM   5246  C CB  . ALA B 1 213 ? 113.548 73.569  114.179 1.00 12.68 ? 192  ALA B CB  1 
ATOM   5247  N N   . GLU B 1 214 ? 112.201 70.582  114.877 1.00 17.07 ? 193  GLU B N   1 
ATOM   5248  C CA  . GLU B 1 214 ? 112.253 69.366  115.681 1.00 17.07 ? 193  GLU B CA  1 
ATOM   5249  C C   . GLU B 1 214 ? 113.576 69.209  116.416 1.00 17.07 ? 193  GLU B C   1 
ATOM   5250  O O   . GLU B 1 214 ? 113.627 68.513  117.434 1.00 17.07 ? 193  GLU B O   1 
ATOM   5251  C CB  . GLU B 1 214 ? 112.002 68.143  114.799 1.00 17.07 ? 193  GLU B CB  1 
ATOM   5252  C CG  . GLU B 1 214 ? 113.173 67.759  113.913 1.00 17.07 ? 193  GLU B CG  1 
ATOM   5253  C CD  . GLU B 1 214 ? 113.117 68.419  112.549 1.00 17.07 ? 193  GLU B CD  1 
ATOM   5254  O OE1 . GLU B 1 214 ? 112.344 69.386  112.387 1.00 17.07 ? 193  GLU B OE1 1 
ATOM   5255  O OE2 . GLU B 1 214 ? 113.848 67.975  111.638 1.00 17.07 ? 193  GLU B OE2 1 
ATOM   5256  N N   . GLN B 1 215 ? 114.646 69.841  115.931 1.00 15.08 ? 194  GLN B N   1 
ATOM   5257  C CA  . GLN B 1 215 ? 115.941 69.721  116.584 1.00 15.08 ? 194  GLN B CA  1 
ATOM   5258  C C   . GLN B 1 215 ? 115.998 70.460  117.912 1.00 15.08 ? 194  GLN B C   1 
ATOM   5259  O O   . GLN B 1 215 ? 116.842 70.129  118.750 1.00 15.08 ? 194  GLN B O   1 
ATOM   5260  C CB  . GLN B 1 215 ? 117.040 70.225  115.656 1.00 15.08 ? 194  GLN B CB  1 
ATOM   5261  C CG  . GLN B 1 215 ? 117.188 69.399  114.396 1.00 15.08 ? 194  GLN B CG  1 
ATOM   5262  C CD  . GLN B 1 215 ? 116.591 70.072  113.180 1.00 15.08 ? 194  GLN B CD  1 
ATOM   5263  O OE1 . GLN B 1 215 ? 115.878 71.068  113.295 1.00 15.08 ? 194  GLN B OE1 1 
ATOM   5264  N NE2 . GLN B 1 215 ? 116.880 69.530  112.004 1.00 15.08 ? 194  GLN B NE2 1 
ATOM   5265  N N   . THR B 1 216 ? 115.131 71.449  118.129 1.00 15.29 ? 195  THR B N   1 
ATOM   5266  C CA  . THR B 1 216 ? 115.097 72.192  119.390 1.00 15.29 ? 195  THR B CA  1 
ATOM   5267  C C   . THR B 1 216 ? 113.657 72.570  119.711 1.00 15.29 ? 195  THR B C   1 
ATOM   5268  O O   . THR B 1 216 ? 113.260 73.735  119.605 1.00 15.29 ? 195  THR B O   1 
ATOM   5269  C CB  . THR B 1 216 ? 115.985 73.431  119.314 1.00 15.29 ? 195  THR B CB  1 
ATOM   5270  O OG1 . THR B 1 216 ? 117.223 73.097  118.676 1.00 15.29 ? 195  THR B OG1 1 
ATOM   5271  C CG2 . THR B 1 216 ? 116.278 73.936  120.702 1.00 15.29 ? 195  THR B CG2 1 
ATOM   5272  N N   . PRO B 1 217 ? 112.838 71.595  120.101 1.00 14.23 ? 196  PRO B N   1 
ATOM   5273  C CA  . PRO B 1 217 ? 111.408 71.854  120.348 1.00 14.23 ? 196  PRO B CA  1 
ATOM   5274  C C   . PRO B 1 217 ? 111.013 72.080  121.804 1.00 14.23 ? 196  PRO B C   1 
ATOM   5275  O O   . PRO B 1 217 ? 109.813 72.163  122.076 1.00 14.23 ? 196  PRO B O   1 
ATOM   5276  C CB  . PRO B 1 217 ? 110.767 70.569  119.817 1.00 14.23 ? 196  PRO B CB  1 
ATOM   5277  C CG  . PRO B 1 217 ? 111.799 69.506  120.082 1.00 14.23 ? 196  PRO B CG  1 
ATOM   5278  C CD  . PRO B 1 217 ? 113.149 70.162  120.213 1.00 14.23 ? 196  PRO B CD  1 
ATOM   5279  N N   . ALA B 1 218 ? 111.960 72.180  122.734 1.00 14.10 ? 197  ALA B N   1 
ATOM   5280  C CA  . ALA B 1 218 ? 111.620 72.257  124.149 1.00 14.10 ? 197  ALA B CA  1 
ATOM   5281  C C   . ALA B 1 218 ? 111.668 73.666  124.720 1.00 14.10 ? 197  ALA B C   1 
ATOM   5282  O O   . ALA B 1 218 ? 110.863 73.986  125.599 1.00 14.10 ? 197  ALA B O   1 
ATOM   5283  C CB  . ALA B 1 218 ? 112.548 71.360  124.973 1.00 14.10 ? 197  ALA B CB  1 
ATOM   5284  N N   . GLY B 1 219 ? 112.593 74.511  124.261 1.00 11.99 ? 198  GLY B N   1 
ATOM   5285  C CA  . GLY B 1 219 ? 112.655 75.866  124.783 1.00 11.99 ? 198  GLY B CA  1 
ATOM   5286  C C   . GLY B 1 219 ? 111.386 76.651  124.516 1.00 11.99 ? 198  GLY B C   1 
ATOM   5287  O O   . GLY B 1 219 ? 110.868 77.339  125.402 1.00 11.99 ? 198  GLY B O   1 
ATOM   5288  N N   . ILE B 1 220 ? 110.861 76.549  123.292 1.00 10.54 ? 199  ILE B N   1 
ATOM   5289  C CA  . ILE B 1 220 ? 109.595 77.193  122.965 1.00 10.54 ? 199  ILE B CA  1 
ATOM   5290  C C   . ILE B 1 220 ? 108.483 76.640  123.839 1.00 10.54 ? 199  ILE B C   1 
ATOM   5291  O O   . ILE B 1 220 ? 107.547 77.361  124.196 1.00 10.54 ? 199  ILE B O   1 
ATOM   5292  C CB  . ILE B 1 220 ? 109.286 77.021  121.466 1.00 10.54 ? 199  ILE B CB  1 
ATOM   5293  C CG1 . ILE B 1 220 ? 110.373 77.680  120.618 1.00 10.54 ? 199  ILE B CG1 1 
ATOM   5294  C CG2 . ILE B 1 220 ? 107.954 77.641  121.116 1.00 10.54 ? 199  ILE B CG2 1 
ATOM   5295  C CD1 . ILE B 1 220 ? 111.325 76.705  119.957 1.00 10.54 ? 199  ILE B CD1 1 
ATOM   5296  N N   . MET B 1 221 ? 108.594 75.373  124.247 1.00 11.65 ? 200  MET B N   1 
ATOM   5297  C CA  . MET B 1 221 ? 107.577 74.768  125.102 1.00 11.65 ? 200  MET B CA  1 
ATOM   5298  C C   . MET B 1 221 ? 107.599 75.352  126.509 1.00 11.65 ? 200  MET B C   1 
ATOM   5299  O O   . MET B 1 221 ? 106.546 75.672  127.064 1.00 11.65 ? 200  MET B O   1 
ATOM   5300  C CB  . MET B 1 221 ? 107.779 73.260  125.161 1.00 11.65 ? 200  MET B CB  1 
ATOM   5301  C CG  . MET B 1 221 ? 107.091 72.474  124.067 1.00 11.65 ? 200  MET B CG  1 
ATOM   5302  S SD  . MET B 1 221 ? 105.370 72.939  123.874 1.00 11.65 ? 200  MET B SD  1 
ATOM   5303  C CE  . MET B 1 221 ? 105.301 73.150  122.111 1.00 11.65 ? 200  MET B CE  1 
ATOM   5304  N N   . VAL B 1 222 ? 108.783 75.493  127.107 1.00 9.41  ? 201  VAL B N   1 
ATOM   5305  C CA  . VAL B 1 222 ? 108.873 76.110  128.430 1.00 9.41  ? 201  VAL B CA  1 
ATOM   5306  C C   . VAL B 1 222 ? 108.398 77.553  128.364 1.00 9.41  ? 201  VAL B C   1 
ATOM   5307  O O   . VAL B 1 222 ? 107.662 78.036  129.239 1.00 9.41  ? 201  VAL B O   1 
ATOM   5308  C CB  . VAL B 1 222 ? 110.310 76.022  128.970 1.00 9.41  ? 201  VAL B CB  1 
ATOM   5309  C CG1 . VAL B 1 222 ? 110.344 76.385  130.443 1.00 9.41  ? 201  VAL B CG1 1 
ATOM   5310  C CG2 . VAL B 1 222 ? 110.880 74.642  128.743 1.00 9.41  ? 201  VAL B CG2 1 
ATOM   5311  N N   . TRP B 1 223 ? 108.824 78.265  127.322 1.00 7.56  ? 202  TRP B N   1 
ATOM   5312  C CA  . TRP B 1 223 ? 108.411 79.649  127.147 1.00 7.56  ? 202  TRP B CA  1 
ATOM   5313  C C   . TRP B 1 223 ? 106.897 79.761  127.056 1.00 7.56  ? 202  TRP B C   1 
ATOM   5314  O O   . TRP B 1 223 ? 106.295 80.636  127.686 1.00 7.56  ? 202  TRP B O   1 
ATOM   5315  C CB  . TRP B 1 223 ? 109.076 80.215  125.900 1.00 7.56  ? 202  TRP B CB  1 
ATOM   5316  C CG  . TRP B 1 223 ? 108.739 81.619  125.616 1.00 7.56  ? 202  TRP B CG  1 
ATOM   5317  C CD1 . TRP B 1 223 ? 109.184 82.718  126.279 1.00 7.56  ? 202  TRP B CD1 1 
ATOM   5318  C CD2 . TRP B 1 223 ? 107.874 82.090  124.587 1.00 7.56  ? 202  TRP B CD2 1 
ATOM   5319  N NE1 . TRP B 1 223 ? 108.654 83.851  125.722 1.00 7.56  ? 202  TRP B NE1 1 
ATOM   5320  C CE2 . TRP B 1 223 ? 107.844 83.490  124.678 1.00 7.56  ? 202  TRP B CE2 1 
ATOM   5321  C CE3 . TRP B 1 223 ? 107.119 81.463  123.596 1.00 7.56  ? 202  TRP B CE3 1 
ATOM   5322  C CZ2 . TRP B 1 223 ? 107.097 84.273  123.813 1.00 7.56  ? 202  TRP B CZ2 1 
ATOM   5323  C CZ3 . TRP B 1 223 ? 106.375 82.238  122.749 1.00 7.56  ? 202  TRP B CZ3 1 
ATOM   5324  C CH2 . TRP B 1 223 ? 106.362 83.629  122.866 1.00 7.56  ? 202  TRP B CH2 1 
ATOM   5325  N N   . ALA B 1 224 ? 106.259 78.871  126.290 1.00 7.54  ? 203  ALA B N   1 
ATOM   5326  C CA  . ALA B 1 224 ? 104.804 78.869  126.204 1.00 7.54  ? 203  ALA B CA  1 
ATOM   5327  C C   . ALA B 1 224 ? 104.160 78.471  127.523 1.00 7.54  ? 203  ALA B C   1 
ATOM   5328  O O   . ALA B 1 224 ? 103.061 78.935  127.835 1.00 7.54  ? 203  ALA B O   1 
ATOM   5329  C CB  . ALA B 1 224 ? 104.345 77.932  125.095 1.00 7.54  ? 203  ALA B CB  1 
ATOM   5330  N N   . ASN B 1 225 ? 104.812 77.602  128.294 1.00 8.87  ? 204  ASN B N   1 
ATOM   5331  C CA  . ASN B 1 225 ? 104.305 77.265  129.620 1.00 8.87  ? 204  ASN B CA  1 
ATOM   5332  C C   . ASN B 1 225 ? 104.220 78.499  130.503 1.00 8.87  ? 204  ASN B C   1 
ATOM   5333  O O   . ASN B 1 225 ? 103.206 78.732  131.171 1.00 8.87  ? 204  ASN B O   1 
ATOM   5334  C CB  . ASN B 1 225 ? 105.196 76.211  130.276 1.00 8.87  ? 204  ASN B CB  1 
ATOM   5335  C CG  . ASN B 1 225 ? 104.643 74.817  130.143 1.00 8.87  ? 204  ASN B CG  1 
ATOM   5336  O OD1 . ASN B 1 225 ? 103.482 74.569  130.461 1.00 8.87  ? 204  ASN B OD1 1 
ATOM   5337  N ND2 . ASN B 1 225 ? 105.473 73.891  129.675 1.00 8.87  ? 204  ASN B ND2 1 
ATOM   5338  N N   . LEU B 1 226 ? 105.279 79.308  130.519 1.00 7.64  ? 205  LEU B N   1 
ATOM   5339  C CA  . LEU B 1 226 ? 105.332 80.389  131.498 1.00 7.64  ? 205  LEU B CA  1 
ATOM   5340  C C   . LEU B 1 226 ? 104.434 81.564  131.111 1.00 7.64  ? 205  LEU B C   1 
ATOM   5341  O O   . LEU B 1 226 ? 103.844 82.201  131.989 1.00 7.64  ? 205  LEU B O   1 
ATOM   5342  C CB  . LEU B 1 226 ? 106.788 80.803  131.739 1.00 7.64  ? 205  LEU B CB  1 
ATOM   5343  C CG  . LEU B 1 226 ? 107.766 81.334  130.690 1.00 7.64  ? 205  LEU B CG  1 
ATOM   5344  C CD1 . LEU B 1 226 ? 107.647 82.815  130.484 1.00 7.64  ? 205  LEU B CD1 1 
ATOM   5345  C CD2 . LEU B 1 226 ? 109.180 80.977  131.103 1.00 7.64  ? 205  LEU B CD2 1 
ATOM   5346  N N   . ILE B 1 227 ? 104.277 81.849  129.817 1.00 6.76  ? 206  ILE B N   1 
ATOM   5347  C CA  . ILE B 1 227 ? 103.373 82.923  129.402 1.00 6.76  ? 206  ILE B CA  1 
ATOM   5348  C C   . ILE B 1 227 ? 102.168 82.405  128.630 1.00 6.76  ? 206  ILE B C   1 
ATOM   5349  O O   . ILE B 1 227 ? 101.657 83.092  127.738 1.00 6.76  ? 206  ILE B O   1 
ATOM   5350  C CB  . ILE B 1 227 ? 104.079 83.989  128.548 1.00 6.76  ? 206  ILE B CB  1 
ATOM   5351  C CG1 . ILE B 1 227 ? 104.653 83.370  127.283 1.00 6.76  ? 206  ILE B CG1 1 
ATOM   5352  C CG2 . ILE B 1 227 ? 105.111 84.754  129.338 1.00 6.76  ? 206  ILE B CG2 1 
ATOM   5353  C CD1 . ILE B 1 227 ? 105.018 84.398  126.299 1.00 6.76  ? 206  ILE B CD1 1 
ATOM   5354  N N   . GLY B 1 228 ? 101.704 81.200  128.946 1.00 8.01  ? 207  GLY B N   1 
ATOM   5355  C CA  . GLY B 1 228 ? 100.552 80.672  128.233 1.00 8.01  ? 207  GLY B CA  1 
ATOM   5356  C C   . GLY B 1 228 ? 99.306  81.514  128.428 1.00 8.01  ? 207  GLY B C   1 
ATOM   5357  O O   . GLY B 1 228 ? 98.594  81.824  127.471 1.00 8.01  ? 207  GLY B O   1 
ATOM   5358  N N   . ASP B 1 229 ? 99.040  81.913  129.666 1.00 8.75  ? 208  ASP B N   1 
ATOM   5359  C CA  . ASP B 1 229 ? 97.784  82.553  130.026 1.00 8.75  ? 208  ASP B CA  1 
ATOM   5360  C C   . ASP B 1 229 ? 97.773  84.052  129.777 1.00 8.75  ? 208  ASP B C   1 
ATOM   5361  O O   . ASP B 1 229 ? 96.740  84.691  130.000 1.00 8.75  ? 208  ASP B O   1 
ATOM   5362  C CB  . ASP B 1 229 ? 97.473  82.287  131.497 1.00 8.75  ? 208  ASP B CB  1 
ATOM   5363  C CG  . ASP B 1 229 ? 98.645  82.599  132.395 1.00 8.75  ? 208  ASP B CG  1 
ATOM   5364  O OD1 . ASP B 1 229 ? 99.689  81.928  132.263 1.00 8.75  ? 208  ASP B OD1 1 
ATOM   5365  O OD2 . ASP B 1 229 ? 98.526  83.520  133.229 1.00 8.75  ? 208  ASP B OD2 1 
ATOM   5366  N N   . LEU B 1 230 ? 98.887  84.636  129.339 1.00 6.45  ? 209  LEU B N   1 
ATOM   5367  C CA  . LEU B 1 230 ? 98.900  86.069  129.069 1.00 6.45  ? 209  LEU B CA  1 
ATOM   5368  C C   . LEU B 1 230 ? 98.135  86.391  127.793 1.00 6.45  ? 209  LEU B C   1 
ATOM   5369  O O   . LEU B 1 230 ? 97.327  87.326  127.759 1.00 6.45  ? 209  LEU B O   1 
ATOM   5370  C CB  . LEU B 1 230 ? 100.337 86.570  128.984 1.00 6.45  ? 209  LEU B CB  1 
ATOM   5371  C CG  . LEU B 1 230 ? 100.912 87.000  130.326 1.00 6.45  ? 209  LEU B CG  1 
ATOM   5372  C CD1 . LEU B 1 230 ? 102.412 87.158  130.236 1.00 6.45  ? 209  LEU B CD1 1 
ATOM   5373  C CD2 . LEU B 1 230 ? 100.259 88.291  130.755 1.00 6.45  ? 209  LEU B CD2 1 
ATOM   5374  N N   . LEU B 1 231 ? 98.373  85.624  126.738 1.00 5.47  ? 210  LEU B N   1 
ATOM   5375  C CA  . LEU B 1 231 ? 97.643  85.769  125.493 1.00 5.47  ? 210  LEU B CA  1 
ATOM   5376  C C   . LEU B 1 231 ? 96.242  85.186  125.638 1.00 5.47  ? 210  LEU B C   1 
ATOM   5377  O O   . LEU B 1 231 ? 95.985  84.389  126.542 1.00 5.47  ? 210  LEU B O   1 
ATOM   5378  C CB  . LEU B 1 231 ? 98.400  85.069  124.371 1.00 5.47  ? 210  LEU B CB  1 
ATOM   5379  C CG  . LEU B 1 231 ? 99.694  85.740  123.917 1.00 5.47  ? 210  LEU B CG  1 
ATOM   5380  C CD1 . LEU B 1 231 ? 100.391 84.904  122.872 1.00 5.47  ? 210  LEU B CD1 1 
ATOM   5381  C CD2 . LEU B 1 231 ? 99.402  87.123  123.383 1.00 5.47  ? 210  LEU B CD2 1 
ATOM   5382  N N   . PRO B 1 232 ? 95.309  85.570  124.771 1.00 6.03  ? 211  PRO B N   1 
ATOM   5383  C CA  . PRO B 1 232 ? 93.991  84.941  124.795 1.00 6.03  ? 211  PRO B CA  1 
ATOM   5384  C C   . PRO B 1 232 ? 94.014  83.629  124.034 1.00 6.03  ? 211  PRO B C   1 
ATOM   5385  O O   . PRO B 1 232 ? 94.833  83.451  123.120 1.00 6.03  ? 211  PRO B O   1 
ATOM   5386  C CB  . PRO B 1 232 ? 93.084  85.977  124.115 1.00 6.03  ? 211  PRO B CB  1 
ATOM   5387  C CG  . PRO B 1 232 ? 93.988  86.854  123.332 1.00 6.03  ? 211  PRO B CG  1 
ATOM   5388  C CD  . PRO B 1 232 ? 95.418  86.569  123.695 1.00 6.03  ? 211  PRO B CD  1 
ATOM   5389  N N   . PRO B 1 233 ? 93.152  82.682  124.398 1.00 6.66  ? 212  PRO B N   1 
ATOM   5390  C CA  . PRO B 1 233 ? 93.228  81.336  123.817 1.00 6.66  ? 212  PRO B CA  1 
ATOM   5391  C C   . PRO B 1 233 ? 93.217  81.352  122.297 1.00 6.66  ? 212  PRO B C   1 
ATOM   5392  O O   . PRO B 1 233 ? 92.439  82.070  121.670 1.00 6.66  ? 212  PRO B O   1 
ATOM   5393  C CB  . PRO B 1 233 ? 91.980  80.643  124.371 1.00 6.66  ? 212  PRO B CB  1 
ATOM   5394  C CG  . PRO B 1 233 ? 91.491  81.497  125.506 1.00 6.66  ? 212  PRO B CG  1 
ATOM   5395  C CD  . PRO B 1 233 ? 92.347  82.712  125.627 1.00 6.66  ? 212  PRO B CD  1 
ATOM   5396  N N   . GLY B 1 234 ? 94.097  80.548  121.704 1.00 5.39  ? 213  GLY B N   1 
ATOM   5397  C CA  . GLY B 1 234 ? 94.159  80.384  120.273 1.00 5.39  ? 213  GLY B CA  1 
ATOM   5398  C C   . GLY B 1 234 ? 95.073  81.350  119.552 1.00 5.39  ? 213  GLY B C   1 
ATOM   5399  O O   . GLY B 1 234 ? 95.428  81.096  118.398 1.00 5.39  ? 213  GLY B O   1 
ATOM   5400  N N   . VAL B 1 235 ? 95.460  82.452  120.194 1.00 5.17  ? 214  VAL B N   1 
ATOM   5401  C CA  . VAL B 1 235 ? 96.353  83.412  119.551 1.00 5.17  ? 214  VAL B CA  1 
ATOM   5402  C C   . VAL B 1 235 ? 97.714  82.784  119.296 1.00 5.17  ? 214  VAL B C   1 
ATOM   5403  O O   . VAL B 1 235 ? 98.298  82.944  118.218 1.00 5.17  ? 214  VAL B O   1 
ATOM   5404  C CB  . VAL B 1 235 ? 96.465  84.688  120.402 1.00 5.17  ? 214  VAL B CB  1 
ATOM   5405  C CG1 . VAL B 1 235 ? 97.667  85.499  119.980 1.00 5.17  ? 214  VAL B CG1 1 
ATOM   5406  C CG2 . VAL B 1 235 ? 95.210  85.503  120.270 1.00 5.17  ? 214  VAL B CG2 1 
ATOM   5407  N N   . LEU B 1 236 ? 98.241  82.063  120.278 1.00 5.16  ? 215  LEU B N   1 
ATOM   5408  C CA  . LEU B 1 236 ? 99.493  81.335  120.142 1.00 5.16  ? 215  LEU B CA  1 
ATOM   5409  C C   . LEU B 1 236 ? 99.178  79.848  120.139 1.00 5.16  ? 215  LEU B C   1 
ATOM   5410  O O   . LEU B 1 236 ? 98.648  79.326  121.124 1.00 5.16  ? 215  LEU B O   1 
ATOM   5411  C CB  . LEU B 1 236 ? 100.452 81.684  121.278 1.00 5.16  ? 215  LEU B CB  1 
ATOM   5412  C CG  . LEU B 1 236 ? 101.864 81.112  121.187 1.00 5.16  ? 215  LEU B CG  1 
ATOM   5413  C CD1 . LEU B 1 236 ? 102.537 81.574  119.911 1.00 5.16  ? 215  LEU B CD1 1 
ATOM   5414  C CD2 . LEU B 1 236 ? 102.675 81.511  122.398 1.00 5.16  ? 215  LEU B CD2 1 
ATOM   5415  N N   . ASN B 1 237 ? 99.494  79.171  119.037 1.00 5.92  ? 216  ASN B N   1 
ATOM   5416  C CA  . ASN B 1 237 ? 99.266  77.738  118.910 1.00 5.92  ? 216  ASN B CA  1 
ATOM   5417  C C   . ASN B 1 237 ? 100.550 77.108  118.412 1.00 5.92  ? 216  ASN B C   1 
ATOM   5418  O O   . ASN B 1 237 ? 100.985 77.401  117.300 1.00 5.92  ? 216  ASN B O   1 
ATOM   5419  C CB  . ASN B 1 237 ? 98.127  77.441  117.934 1.00 5.92  ? 216  ASN B CB  1 
ATOM   5420  C CG  . ASN B 1 237 ? 96.864  78.169  118.286 1.00 5.92  ? 216  ASN B CG  1 
ATOM   5421  O OD1 . ASN B 1 237 ? 96.345  78.035  119.389 1.00 5.92  ? 216  ASN B OD1 1 
ATOM   5422  N ND2 . ASN B 1 237 ? 96.357  78.955  117.348 1.00 5.92  ? 216  ASN B ND2 1 
ATOM   5423  N N   . ILE B 1 238 ? 101.138 76.223  119.204 1.00 6.98  ? 217  ILE B N   1 
ATOM   5424  C CA  . ILE B 1 238 ? 102.458 75.692  118.908 1.00 6.98  ? 217  ILE B CA  1 
ATOM   5425  C C   . ILE B 1 238 ? 102.320 74.196  118.676 1.00 6.98  ? 217  ILE B C   1 
ATOM   5426  O O   . ILE B 1 238 ? 101.725 73.492  119.498 1.00 6.98  ? 217  ILE B O   1 
ATOM   5427  C CB  . ILE B 1 238 ? 103.442 75.982  120.050 1.00 6.98  ? 217  ILE B CB  1 
ATOM   5428  C CG1 . ILE B 1 238 ? 103.605 77.483  120.224 1.00 6.98  ? 217  ILE B CG1 1 
ATOM   5429  C CG2 . ILE B 1 238 ? 104.797 75.470  119.677 1.00 6.98  ? 217  ILE B CG2 1 
ATOM   5430  C CD1 . ILE B 1 238 ? 104.336 77.861  121.472 1.00 6.98  ? 217  ILE B CD1 1 
ATOM   5431  N N   . VAL B 1 239 ? 102.855 73.714  117.556 1.00 9.11  ? 218  VAL B N   1 
ATOM   5432  C CA  . VAL B 1 239 ? 102.793 72.304  117.189 1.00 9.11  ? 218  VAL B CA  1 
ATOM   5433  C C   . VAL B 1 239 ? 104.182 71.839  116.768 1.00 9.11  ? 218  VAL B C   1 
ATOM   5434  O O   . VAL B 1 239 ? 104.859 72.511  115.982 1.00 9.11  ? 218  VAL B O   1 
ATOM   5435  C CB  . VAL B 1 239 ? 101.765 72.046  116.069 1.00 9.11  ? 218  VAL B CB  1 
ATOM   5436  C CG1 . VAL B 1 239 ? 100.381 72.458  116.517 1.00 9.11  ? 218  VAL B CG1 1 
ATOM   5437  C CG2 . VAL B 1 239 ? 102.134 72.807  114.820 1.00 9.11  ? 218  VAL B CG2 1 
ATOM   5438  N N   . ASN B 1 240 ? 104.609 70.698  117.295 1.00 13.21 ? 219  ASN B N   1 
ATOM   5439  C CA  . ASN B 1 240 ? 105.912 70.133  116.980 1.00 13.21 ? 219  ASN B CA  1 
ATOM   5440  C C   . ASN B 1 240 ? 105.785 69.058  115.908 1.00 13.21 ? 219  ASN B C   1 
ATOM   5441  O O   . ASN B 1 240 ? 104.697 68.553  115.624 1.00 13.21 ? 219  ASN B O   1 
ATOM   5442  C CB  . ASN B 1 240 ? 106.557 69.542  118.232 1.00 13.21 ? 219  ASN B CB  1 
ATOM   5443  C CG  . ASN B 1 240 ? 106.552 70.503  119.397 1.00 13.21 ? 219  ASN B CG  1 
ATOM   5444  O OD1 . ASN B 1 240 ? 105.760 70.361  120.326 1.00 13.21 ? 219  ASN B OD1 1 
ATOM   5445  N ND2 . ASN B 1 240 ? 107.442 71.483  119.359 1.00 13.21 ? 219  ASN B ND2 1 
ATOM   5446  N N   . GLY B 1 241 ? 106.916 68.710  115.315 1.00 16.24 ? 220  GLY B N   1 
ATOM   5447  C CA  . GLY B 1 241 ? 106.938 67.680  114.299 1.00 16.24 ? 220  GLY B CA  1 
ATOM   5448  C C   . GLY B 1 241 ? 108.118 67.876  113.369 1.00 16.24 ? 220  GLY B C   1 
ATOM   5449  O O   . GLY B 1 241 ? 108.893 68.820  113.509 1.00 16.24 ? 220  GLY B O   1 
ATOM   5450  N N   . PHE B 1 242 ? 108.231 66.958  112.416 1.00 21.32 ? 221  PHE B N   1 
ATOM   5451  C CA  . PHE B 1 242 ? 109.295 67.000  111.427 1.00 21.32 ? 221  PHE B CA  1 
ATOM   5452  C C   . PHE B 1 242 ? 108.867 67.851  110.233 1.00 21.32 ? 221  PHE B C   1 
ATOM   5453  O O   . PHE B 1 242 ? 107.718 68.283  110.118 1.00 21.32 ? 221  PHE B O   1 
ATOM   5454  C CB  . PHE B 1 242 ? 109.696 65.588  110.992 1.00 21.32 ? 221  PHE B CB  1 
ATOM   5455  C CG  . PHE B 1 242 ? 109.897 64.625  112.133 1.00 21.32 ? 221  PHE B CG  1 
ATOM   5456  C CD1 . PHE B 1 242 ? 110.368 65.063  113.361 1.00 21.32 ? 221  PHE B CD1 1 
ATOM   5457  C CD2 . PHE B 1 242 ? 109.655 63.273  111.963 1.00 21.32 ? 221  PHE B CD2 1 
ATOM   5458  C CE1 . PHE B 1 242 ? 110.559 64.179  114.403 1.00 21.32 ? 221  PHE B CE1 1 
ATOM   5459  C CE2 . PHE B 1 242 ? 109.849 62.386  113.003 1.00 21.32 ? 221  PHE B CE2 1 
ATOM   5460  C CZ  . PHE B 1 242 ? 110.302 62.841  114.223 1.00 21.32 ? 221  PHE B CZ  1 
ATOM   5461  N N   . GLY B 1 243 ? 109.812 68.089  109.329 1.00 18.88 ? 222  GLY B N   1 
ATOM   5462  C CA  . GLY B 1 243 ? 109.627 69.023  108.239 1.00 18.88 ? 222  GLY B CA  1 
ATOM   5463  C C   . GLY B 1 243 ? 108.858 68.524  107.039 1.00 18.88 ? 222  GLY B C   1 
ATOM   5464  O O   . GLY B 1 243 ? 108.684 69.278  106.078 1.00 18.88 ? 222  GLY B O   1 
ATOM   5465  N N   . LEU B 1 244 ? 108.397 67.276  107.046 1.00 20.51 ? 223  LEU B N   1 
ATOM   5466  C CA  . LEU B 1 244 ? 107.572 66.764  105.965 1.00 20.51 ? 223  LEU B CA  1 
ATOM   5467  C C   . LEU B 1 244 ? 106.181 66.344  106.417 1.00 20.51 ? 223  LEU B C   1 
ATOM   5468  O O   . LEU B 1 244 ? 105.341 66.039  105.565 1.00 20.51 ? 223  LEU B O   1 
ATOM   5469  C CB  . LEU B 1 244 ? 108.258 65.578  105.270 1.00 20.51 ? 223  LEU B CB  1 
ATOM   5470  C CG  . LEU B 1 244 ? 109.314 65.828  104.183 1.00 20.51 ? 223  LEU B CG  1 
ATOM   5471  C CD1 . LEU B 1 244 ? 108.696 66.529  102.979 1.00 20.51 ? 223  LEU B CD1 1 
ATOM   5472  C CD2 . LEU B 1 244 ? 110.530 66.590  104.695 1.00 20.51 ? 223  LEU B CD2 1 
ATOM   5473  N N   . GLU B 1 245 ? 105.907 66.324  107.718 1.00 22.00 ? 224  GLU B N   1 
ATOM   5474  C CA  . GLU B 1 245 ? 104.615 65.881  108.223 1.00 22.00 ? 224  GLU B CA  1 
ATOM   5475  C C   . GLU B 1 245 ? 103.846 66.948  108.984 1.00 22.00 ? 224  GLU B C   1 
ATOM   5476  O O   . GLU B 1 245 ? 102.617 66.956  108.924 1.00 22.00 ? 224  GLU B O   1 
ATOM   5477  C CB  . GLU B 1 245 ? 104.788 64.655  109.129 1.00 22.00 ? 224  GLU B CB  1 
ATOM   5478  C CG  . GLU B 1 245 ? 105.639 64.911  110.349 1.00 22.00 ? 224  GLU B CG  1 
ATOM   5479  C CD  . GLU B 1 245 ? 105.954 63.649  111.107 1.00 22.00 ? 224  GLU B CD  1 
ATOM   5480  O OE1 . GLU B 1 245 ? 105.560 62.559  110.641 1.00 22.00 ? 224  GLU B OE1 1 
ATOM   5481  O OE2 . GLU B 1 245 ? 106.597 63.746  112.171 1.00 22.00 ? 224  GLU B OE2 1 
ATOM   5482  N N   . ALA B 1 246 ? 104.526 67.838  109.702 1.00 19.79 ? 225  ALA B N   1 
ATOM   5483  C CA  . ALA B 1 246 ? 103.880 68.961  110.359 1.00 19.79 ? 225  ALA B CA  1 
ATOM   5484  C C   . ALA B 1 246 ? 104.293 70.302  109.780 1.00 19.79 ? 225  ALA B C   1 
ATOM   5485  O O   . ALA B 1 246 ? 103.711 71.324  110.156 1.00 19.79 ? 225  ALA B O   1 
ATOM   5486  C CB  . ALA B 1 246 ? 104.183 68.953  111.863 1.00 19.79 ? 225  ALA B CB  1 
ATOM   5487  N N   . GLY B 1 247 ? 105.279 70.325  108.886 1.00 19.71 ? 226  GLY B N   1 
ATOM   5488  C CA  . GLY B 1 247 ? 105.741 71.559  108.290 1.00 19.71 ? 226  GLY B CA  1 
ATOM   5489  C C   . GLY B 1 247 ? 105.033 71.875  106.993 1.00 19.71 ? 226  GLY B C   1 
ATOM   5490  O O   . GLY B 1 247 ? 104.537 72.988  106.808 1.00 19.71 ? 226  GLY B O   1 
ATOM   5491  N N   . LYS B 1 248 ? 104.988 70.904  106.084 1.00 21.62 ? 227  LYS B N   1 
ATOM   5492  C CA  . LYS B 1 248 ? 104.261 71.103  104.834 1.00 21.62 ? 227  LYS B CA  1 
ATOM   5493  C C   . LYS B 1 248 ? 102.772 71.370  105.034 1.00 21.62 ? 227  LYS B C   1 
ATOM   5494  O O   . LYS B 1 248 ? 102.249 72.279  104.367 1.00 21.62 ? 227  LYS B O   1 
ATOM   5495  C CB  . LYS B 1 248 ? 104.479 69.905  103.903 1.00 21.62 ? 227  LYS B CB  1 
ATOM   5496  C CG  . LYS B 1 248 ? 104.070 70.179  102.470 1.00 21.62 ? 227  LYS B CG  1 
ATOM   5497  C CD  . LYS B 1 248 ? 104.110 68.925  101.619 1.00 21.62 ? 227  LYS B CD  1 
ATOM   5498  C CE  . LYS B 1 248 ? 103.188 69.049  100.415 1.00 21.62 ? 227  LYS B CE  1 
ATOM   5499  N NZ  . LYS B 1 248 ? 101.769 68.754  100.759 1.00 21.62 ? 227  LYS B NZ  1 
ATOM   5500  N N   . PRO B 1 249 ? 102.037 70.644  105.890 1.00 18.87 ? 228  PRO B N   1 
ATOM   5501  C CA  . PRO B 1 249 ? 100.615 70.985  106.075 1.00 18.87 ? 228  PRO B CA  1 
ATOM   5502  C C   . PRO B 1 249 ? 100.387 72.411  106.537 1.00 18.87 ? 228  PRO B C   1 
ATOM   5503  O O   . PRO B 1 249 ? 99.404  73.039  106.130 1.00 18.87 ? 228  PRO B O   1 
ATOM   5504  C CB  . PRO B 1 249 ? 100.153 69.972  107.128 1.00 18.87 ? 228  PRO B CB  1 
ATOM   5505  C CG  . PRO B 1 249 ? 101.051 68.837  106.963 1.00 18.87 ? 228  PRO B CG  1 
ATOM   5506  C CD  . PRO B 1 249 ? 102.387 69.416  106.624 1.00 18.87 ? 228  PRO B CD  1 
ATOM   5507  N N   . LEU B 1 250 ? 101.264 72.938  107.390 1.00 15.70 ? 229  LEU B N   1 
ATOM   5508  C CA  . LEU B 1 250 ? 101.122 74.322  107.825 1.00 15.70 ? 229  LEU B CA  1 
ATOM   5509  C C   . LEU B 1 250 ? 101.530 75.289  106.725 1.00 15.70 ? 229  LEU B C   1 
ATOM   5510  O O   . LEU B 1 250 ? 100.868 76.308  106.510 1.00 15.70 ? 229  LEU B O   1 
ATOM   5511  C CB  . LEU B 1 250 ? 101.955 74.563  109.081 1.00 15.70 ? 229  LEU B CB  1 
ATOM   5512  C CG  . LEU B 1 250 ? 102.311 76.019  109.367 1.00 15.70 ? 229  LEU B CG  1 
ATOM   5513  C CD1 . LEU B 1 250 ? 101.100 76.759  109.895 1.00 15.70 ? 229  LEU B CD1 1 
ATOM   5514  C CD2 . LEU B 1 250 ? 103.462 76.093  110.344 1.00 15.70 ? 229  LEU B CD2 1 
ATOM   5515  N N   . ALA B 1 251 ? 102.609 74.981  106.010 1.00 16.41 ? 230  ALA B N   1 
ATOM   5516  C CA  . ALA B 1 251 ? 103.166 75.862  104.996 1.00 16.41 ? 230  ALA B CA  1 
ATOM   5517  C C   . ALA B 1 251 ? 102.542 75.660  103.627 1.00 16.41 ? 230  ALA B C   1 
ATOM   5518  O O   . ALA B 1 251 ? 103.066 76.183  102.640 1.00 16.41 ? 230  ALA B O   1 
ATOM   5519  C CB  . ALA B 1 251 ? 104.676 75.665  104.900 1.00 16.41 ? 230  ALA B CB  1 
ATOM   5520  N N   . SER B 1 252 ? 101.448 74.905  103.541 1.00 18.09 ? 231  SER B N   1 
ATOM   5521  C CA  . SER B 1 252 ? 100.746 74.748  102.274 1.00 18.09 ? 231  SER B CA  1 
ATOM   5522  C C   . SER B 1 252 ? 99.247  74.952  102.437 1.00 18.09 ? 231  SER B C   1 
ATOM   5523  O O   . SER B 1 252 ? 98.508  74.847  101.454 1.00 18.09 ? 231  SER B O   1 
ATOM   5524  C CB  . SER B 1 252 ? 101.016 73.372  101.660 1.00 18.09 ? 231  SER B CB  1 
ATOM   5525  O OG  . SER B 1 252 ? 100.097 72.407  102.141 1.00 18.09 ? 231  SER B OG  1 
ATOM   5526  N N   . SER B 1 253 ? 98.785  75.255  103.643 1.00 17.62 ? 232  SER B N   1 
ATOM   5527  C CA  . SER B 1 253 ? 97.369  75.442  103.899 1.00 17.62 ? 232  SER B CA  1 
ATOM   5528  C C   . SER B 1 253 ? 96.853  76.690  103.201 1.00 17.62 ? 232  SER B C   1 
ATOM   5529  O O   . SER B 1 253 ? 97.583  77.662  102.999 1.00 17.62 ? 232  SER B O   1 
ATOM   5530  C CB  . SER B 1 253 ? 97.098  75.548  105.398 1.00 17.62 ? 232  SER B CB  1 
ATOM   5531  O OG  . SER B 1 253 ? 97.215  74.286  106.026 1.00 17.62 ? 232  SER B OG  1 
ATOM   5532  N N   . ASN B 1 254 ? 95.581  76.646  102.826 1.00 19.70 ? 233  ASN B N   1 
ATOM   5533  C CA  . ASN B 1 254 ? 94.882  77.829  102.350 1.00 19.70 ? 233  ASN B CA  1 
ATOM   5534  C C   . ASN B 1 254 ? 94.242  78.616  103.482 1.00 19.70 ? 233  ASN B C   1 
ATOM   5535  O O   . ASN B 1 254 ? 93.639  79.662  103.228 1.00 19.70 ? 233  ASN B O   1 
ATOM   5536  C CB  . ASN B 1 254 ? 93.830  77.435  101.308 1.00 19.70 ? 233  ASN B CB  1 
ATOM   5537  C CG  . ASN B 1 254 ? 92.797  76.461  101.847 1.00 19.70 ? 233  ASN B CG  1 
ATOM   5538  O OD1 . ASN B 1 254 ? 92.687  76.242  103.054 1.00 19.70 ? 233  ASN B OD1 1 
ATOM   5539  N ND2 . ASN B 1 254 ? 92.046  75.850  100.940 1.00 19.70 ? 233  ASN B ND2 1 
ATOM   5540  N N   . ARG B 1 255 ? 94.355  78.135  104.716 1.00 13.15 ? 234  ARG B N   1 
ATOM   5541  C CA  . ARG B 1 255 ? 93.821  78.838  105.870 1.00 13.15 ? 234  ARG B CA  1 
ATOM   5542  C C   . ARG B 1 255 ? 94.804  79.830  106.472 1.00 13.15 ? 234  ARG B C   1 
ATOM   5543  O O   . ARG B 1 255 ? 94.429  80.560  107.396 1.00 13.15 ? 234  ARG B O   1 
ATOM   5544  C CB  . ARG B 1 255 ? 93.391  77.838  106.945 1.00 13.15 ? 234  ARG B CB  1 
ATOM   5545  C CG  . ARG B 1 255 ? 91.977  77.334  106.789 1.00 13.15 ? 234  ARG B CG  1 
ATOM   5546  C CD  . ARG B 1 255 ? 91.818  75.957  107.402 1.00 13.15 ? 234  ARG B CD  1 
ATOM   5547  N NE  . ARG B 1 255 ? 91.442  76.021  108.809 1.00 13.15 ? 234  ARG B NE  1 
ATOM   5548  C CZ  . ARG B 1 255 ? 90.277  76.476  109.261 1.00 13.15 ? 234  ARG B CZ  1 
ATOM   5549  N NH1 . ARG B 1 255 ? 89.352  76.910  108.419 1.00 13.15 ? 234  ARG B NH1 1 
ATOM   5550  N NH2 . ARG B 1 255 ? 90.035  76.491  110.563 1.00 13.15 ? 234  ARG B NH2 1 
ATOM   5551  N N   . ILE B 1 256 ? 96.046  79.873  105.985 1.00 10.64 ? 235  ILE B N   1 
ATOM   5552  C CA  . ILE B 1 256 ? 97.024  80.845  106.452 1.00 10.64 ? 235  ILE B CA  1 
ATOM   5553  C C   . ILE B 1 256 ? 97.110  81.975  105.441 1.00 10.64 ? 235  ILE B C   1 
ATOM   5554  O O   . ILE B 1 256 ? 96.964  81.776  104.231 1.00 10.64 ? 235  ILE B O   1 
ATOM   5555  C CB  . ILE B 1 256 ? 98.416  80.223  106.701 1.00 10.64 ? 235  ILE B CB  1 
ATOM   5556  C CG1 . ILE B 1 256 ? 99.061  79.771  105.395 1.00 10.64 ? 235  ILE B CG1 1 
ATOM   5557  C CG2 . ILE B 1 256 ? 98.329  79.074  107.674 1.00 10.64 ? 235  ILE B CG2 1 
ATOM   5558  C CD1 . ILE B 1 256 ? 100.515 79.420  105.545 1.00 10.64 ? 235  ILE B CD1 1 
ATOM   5559  N N   . ALA B 1 257 ? 97.330  83.183  105.949 1.00 9.12  ? 236  ALA B N   1 
ATOM   5560  C CA  . ALA B 1 257 ? 97.512  84.347  105.097 1.00 9.12  ? 236  ALA B CA  1 
ATOM   5561  C C   . ALA B 1 257 ? 98.958  84.510  104.659 1.00 9.12  ? 236  ALA B C   1 
ATOM   5562  O O   . ALA B 1 257 ? 99.222  84.944  103.534 1.00 9.12  ? 236  ALA B O   1 
ATOM   5563  C CB  . ALA B 1 257 ? 97.046  85.607  105.824 1.00 9.12  ? 236  ALA B CB  1 
ATOM   5564  N N   . LYS B 1 258 ? 99.898  84.167  105.532 1.00 9.73  ? 237  LYS B N   1 
ATOM   5565  C CA  . LYS B 1 258 ? 101.314 84.337  105.267 1.00 9.73  ? 237  LYS B CA  1 
ATOM   5566  C C   . LYS B 1 258 ? 102.075 83.180  105.893 1.00 9.73  ? 237  LYS B C   1 
ATOM   5567  O O   . LYS B 1 258 ? 101.683 82.662  106.939 1.00 9.73  ? 237  LYS B O   1 
ATOM   5568  C CB  . LYS B 1 258 ? 101.808 85.676  105.823 1.00 9.73  ? 237  LYS B CB  1 
ATOM   5569  C CG  . LYS B 1 258 ? 103.151 86.129  105.308 1.00 9.73  ? 237  LYS B CG  1 
ATOM   5570  C CD  . LYS B 1 258 ? 103.599 87.351  106.068 1.00 9.73  ? 237  LYS B CD  1 
ATOM   5571  C CE  . LYS B 1 258 ? 105.015 87.723  105.721 1.00 9.73  ? 237  LYS B CE  1 
ATOM   5572  N NZ  . LYS B 1 258 ? 105.213 87.893  104.258 1.00 9.73  ? 237  LYS B NZ  1 
ATOM   5573  N N   . ILE B 1 259 ? 103.149 82.763  105.232 1.00 11.24 ? 238  ILE B N   1 
ATOM   5574  C CA  . ILE B 1 259 ? 104.045 81.736  105.748 1.00 11.24 ? 238  ILE B CA  1 
ATOM   5575  C C   . ILE B 1 259 ? 105.432 82.348  105.899 1.00 11.24 ? 238  ILE B C   1 
ATOM   5576  O O   . ILE B 1 259 ? 106.028 82.823  104.925 1.00 11.24 ? 238  ILE B O   1 
ATOM   5577  C CB  . ILE B 1 259 ? 104.066 80.475  104.864 1.00 11.24 ? 238  ILE B CB  1 
ATOM   5578  C CG1 . ILE B 1 259 ? 104.903 79.372  105.515 1.00 11.24 ? 238  ILE B CG1 1 
ATOM   5579  C CG2 . ILE B 1 259 ? 104.501 80.763  103.432 1.00 11.24 ? 238  ILE B CG2 1 
ATOM   5580  C CD1 . ILE B 1 259 ? 104.308 78.829  106.780 1.00 11.24 ? 238  ILE B CD1 1 
ATOM   5581  N N   . ALA B 1 260 ? 105.931 82.368  107.128 1.00 12.04 ? 239  ALA B N   1 
ATOM   5582  C CA  . ALA B 1 260 ? 107.278 82.830  107.425 1.00 12.04 ? 239  ALA B CA  1 
ATOM   5583  C C   . ALA B 1 260 ? 108.167 81.616  107.632 1.00 12.04 ? 239  ALA B C   1 
ATOM   5584  O O   . ALA B 1 260 ? 107.800 80.693  108.363 1.00 12.04 ? 239  ALA B O   1 
ATOM   5585  C CB  . ALA B 1 260 ? 107.296 83.722  108.667 1.00 12.04 ? 239  ALA B CB  1 
ATOM   5586  N N   . PHE B 1 261 ? 109.317 81.605  106.974 1.00 15.71 ? 240  PHE B N   1 
ATOM   5587  C CA  . PHE B 1 261 ? 110.260 80.512  107.112 1.00 15.71 ? 240  PHE B CA  1 
ATOM   5588  C C   . PHE B 1 261 ? 111.652 81.076  107.341 1.00 15.71 ? 240  PHE B C   1 
ATOM   5589  O O   . PHE B 1 261 ? 111.980 82.168  106.875 1.00 15.71 ? 240  PHE B O   1 
ATOM   5590  C CB  . PHE B 1 261 ? 110.252 79.604  105.880 1.00 15.71 ? 240  PHE B CB  1 
ATOM   5591  C CG  . PHE B 1 261 ? 111.382 78.624  105.847 1.00 15.71 ? 240  PHE B CG  1 
ATOM   5592  C CD1 . PHE B 1 261 ? 111.436 77.584  106.755 1.00 15.71 ? 240  PHE B CD1 1 
ATOM   5593  C CD2 . PHE B 1 261 ? 112.394 78.743  104.911 1.00 15.71 ? 240  PHE B CD2 1 
ATOM   5594  C CE1 . PHE B 1 261 ? 112.476 76.682  106.729 1.00 15.71 ? 240  PHE B CE1 1 
ATOM   5595  C CE2 . PHE B 1 261 ? 113.436 77.842  104.882 1.00 15.71 ? 240  PHE B CE2 1 
ATOM   5596  C CZ  . PHE B 1 261 ? 113.478 76.815  105.792 1.00 15.71 ? 240  PHE B CZ  1 
ATOM   5597  N N   . THR B 1 262 ? 112.463 80.324  108.080 1.00 15.12 ? 241  THR B N   1 
ATOM   5598  C CA  . THR B 1 262 ? 113.851 80.692  108.317 1.00 15.12 ? 241  THR B CA  1 
ATOM   5599  C C   . THR B 1 262 ? 114.667 79.413  108.368 1.00 15.12 ? 241  THR B C   1 
ATOM   5600  O O   . THR B 1 262 ? 114.324 78.493  109.114 1.00 15.12 ? 241  THR B O   1 
ATOM   5601  C CB  . THR B 1 262 ? 114.006 81.473  109.625 1.00 15.12 ? 241  THR B CB  1 
ATOM   5602  O OG1 . THR B 1 262 ? 113.136 82.606  109.605 1.00 15.12 ? 241  THR B OG1 1 
ATOM   5603  C CG2 . THR B 1 262 ? 115.436 81.963  109.780 1.00 15.12 ? 241  THR B CG2 1 
ATOM   5604  N N   . GLY B 1 263 ? 115.730 79.349  107.575 1.00 20.07 ? 242  GLY B N   1 
ATOM   5605  C CA  . GLY B 1 263 ? 116.550 78.157  107.572 1.00 20.07 ? 242  GLY B CA  1 
ATOM   5606  C C   . GLY B 1 263 ? 117.326 77.919  106.297 1.00 20.07 ? 242  GLY B C   1 
ATOM   5607  O O   . GLY B 1 263 ? 118.032 78.807  105.814 1.00 20.07 ? 242  GLY B O   1 
ATOM   5608  N N   . GLU B 1 264 ? 117.204 76.715  105.750 1.00 25.50 ? 243  GLU B N   1 
ATOM   5609  C CA  . GLU B 1 264 ? 117.998 76.290  104.608 1.00 25.50 ? 243  GLU B CA  1 
ATOM   5610  C C   . GLU B 1 264 ? 117.345 76.713  103.297 1.00 25.50 ? 243  GLU B C   1 
ATOM   5611  O O   . GLU B 1 264 ? 116.119 76.755  103.174 1.00 25.50 ? 243  GLU B O   1 
ATOM   5612  C CB  . GLU B 1 264 ? 118.208 74.772  104.629 1.00 25.50 ? 243  GLU B CB  1 
ATOM   5613  C CG  . GLU B 1 264 ? 118.689 74.188  105.966 1.00 25.50 ? 243  GLU B CG  1 
ATOM   5614  C CD  . GLU B 1 264 ? 117.606 74.090  107.036 1.00 25.50 ? 243  GLU B CD  1 
ATOM   5615  O OE1 . GLU B 1 264 ? 116.449 74.480  106.766 1.00 25.50 ? 243  GLU B OE1 1 
ATOM   5616  O OE2 . GLU B 1 264 ? 117.921 73.626  108.153 1.00 25.50 ? 243  GLU B OE2 1 
ATOM   5617  N N   . THR B 1 265 ? 118.190 77.023  102.311 1.00 25.77 ? 244  THR B N   1 
ATOM   5618  C CA  . THR B 1 265 ? 117.708 77.584  101.052 1.00 25.77 ? 244  THR B CA  1 
ATOM   5619  C C   . THR B 1 265 ? 116.805 76.611  100.302 1.00 25.77 ? 244  THR B C   1 
ATOM   5620  O O   . THR B 1 265 ? 115.774 77.013  99.749  1.00 25.77 ? 244  THR B O   1 
ATOM   5621  C CB  . THR B 1 265 ? 118.891 77.992  100.176 1.00 25.77 ? 244  THR B CB  1 
ATOM   5622  O OG1 . THR B 1 265 ? 119.687 76.842  99.872  1.00 25.77 ? 244  THR B OG1 1 
ATOM   5623  C CG2 . THR B 1 265 ? 119.748 79.032  100.883 1.00 25.77 ? 244  THR B CG2 1 
ATOM   5624  N N   . THR B 1 266 ? 117.183 75.332  100.252 1.00 27.13 ? 245  THR B N   1 
ATOM   5625  C CA  . THR B 1 266 ? 116.351 74.349  99.562  1.00 27.13 ? 245  THR B CA  1 
ATOM   5626  C C   . THR B 1 266 ? 115.002 74.186  100.253 1.00 27.13 ? 245  THR B C   1 
ATOM   5627  O O   . THR B 1 266 ? 113.964 74.079  99.588  1.00 27.13 ? 245  THR B O   1 
ATOM   5628  C CB  . THR B 1 266 ? 117.081 73.008  99.474  1.00 27.13 ? 245  THR B CB  1 
ATOM   5629  O OG1 . THR B 1 266 ? 118.401 73.215  98.956  1.00 27.13 ? 245  THR B OG1 1 
ATOM   5630  C CG2 . THR B 1 266 ? 116.332 72.053  98.562  1.00 27.13 ? 245  THR B CG2 1 
ATOM   5631  N N   . THR B 1 267 ? 114.996 74.166  101.586 1.00 26.27 ? 246  THR B N   1 
ATOM   5632  C CA  . THR B 1 267 ? 113.727 74.154  102.304 1.00 26.27 ? 246  THR B CA  1 
ATOM   5633  C C   . THR B 1 267 ? 112.924 75.414  102.011 1.00 26.27 ? 246  THR B C   1 
ATOM   5634  O O   . THR B 1 267 ? 111.690 75.370  101.967 1.00 26.27 ? 246  THR B O   1 
ATOM   5635  C CB  . THR B 1 267 ? 113.971 74.015  103.806 1.00 26.27 ? 246  THR B CB  1 
ATOM   5636  O OG1 . THR B 1 267 ? 114.868 72.925  104.046 1.00 26.27 ? 246  THR B OG1 1 
ATOM   5637  C CG2 . THR B 1 267 ? 112.666 73.730  104.522 1.00 26.27 ? 246  THR B CG2 1 
ATOM   5638  N N   . GLY B 1 268 ? 113.607 76.540  101.792 1.00 24.18 ? 247  GLY B N   1 
ATOM   5639  C CA  . GLY B 1 268 ? 112.909 77.758  101.416 1.00 24.18 ? 247  GLY B CA  1 
ATOM   5640  C C   . GLY B 1 268 ? 112.257 77.660  100.051 1.00 24.18 ? 247  GLY B C   1 
ATOM   5641  O O   . GLY B 1 268 ? 111.146 78.155  99.848  1.00 24.18 ? 247  GLY B O   1 
ATOM   5642  N N   . ARG B 1 269 ? 112.935 77.018  99.098  1.00 26.40 ? 248  ARG B N   1 
ATOM   5643  C CA  . ARG B 1 269 ? 112.316 76.775  97.798  1.00 26.40 ? 248  ARG B CA  1 
ATOM   5644  C C   . ARG B 1 269 ? 111.123 75.839  97.928  1.00 26.40 ? 248  ARG B C   1 
ATOM   5645  O O   . ARG B 1 269 ? 110.106 76.023  97.249  1.00 26.40 ? 248  ARG B O   1 
ATOM   5646  C CB  . ARG B 1 269 ? 113.338 76.205  96.820  1.00 26.40 ? 248  ARG B CB  1 
ATOM   5647  C CG  . ARG B 1 269 ? 114.336 77.222  96.325  1.00 26.40 ? 248  ARG B CG  1 
ATOM   5648  C CD  . ARG B 1 269 ? 115.634 76.569  95.914  1.00 26.40 ? 248  ARG B CD  1 
ATOM   5649  N NE  . ARG B 1 269 ? 116.677 77.560  95.675  1.00 26.40 ? 248  ARG B NE  1 
ATOM   5650  C CZ  . ARG B 1 269 ? 117.042 77.983  94.470  1.00 26.40 ? 248  ARG B CZ  1 
ATOM   5651  N NH1 . ARG B 1 269 ? 116.449 77.501  93.388  1.00 26.40 ? 248  ARG B NH1 1 
ATOM   5652  N NH2 . ARG B 1 269 ? 118.002 78.889  94.347  1.00 26.40 ? 248  ARG B NH2 1 
ATOM   5653  N N   . LEU B 1 270 ? 111.236 74.824  98.786  1.00 26.87 ? 249  LEU B N   1 
ATOM   5654  C CA  . LEU B 1 270 ? 110.092 73.959  99.065  1.00 26.87 ? 249  LEU B CA  1 
ATOM   5655  C C   . LEU B 1 270 ? 108.914 74.770  99.589  1.00 26.87 ? 249  LEU B C   1 
ATOM   5656  O O   . LEU B 1 270 ? 107.772 74.594  99.145  1.00 26.87 ? 249  LEU B O   1 
ATOM   5657  C CB  . LEU B 1 270 ? 110.481 72.879  100.072 1.00 26.87 ? 249  LEU B CB  1 
ATOM   5658  C CG  . LEU B 1 270 ? 110.979 71.537  99.540  1.00 26.87 ? 249  LEU B CG  1 
ATOM   5659  C CD1 . LEU B 1 270 ? 111.179 70.567  100.692 1.00 26.87 ? 249  LEU B CD1 1 
ATOM   5660  C CD2 . LEU B 1 270 ? 110.014 70.966  98.517  1.00 26.87 ? 249  LEU B CD2 1 
ATOM   5661  N N   . ILE B 1 271 ? 109.179 75.673  100.535 1.00 24.17 ? 250  ILE B N   1 
ATOM   5662  C CA  . ILE B 1 271 ? 108.124 76.506  101.102 1.00 24.17 ? 250  ILE B CA  1 
ATOM   5663  C C   . ILE B 1 271 ? 107.504 77.394  100.030 1.00 24.17 ? 250  ILE B C   1 
ATOM   5664  O O   . ILE B 1 271 ? 106.280 77.567  99.980  1.00 24.17 ? 250  ILE B O   1 
ATOM   5665  C CB  . ILE B 1 271 ? 108.675 77.338  102.274 1.00 24.17 ? 250  ILE B CB  1 
ATOM   5666  C CG1 . ILE B 1 271 ? 109.098 76.425  103.422 1.00 24.17 ? 250  ILE B CG1 1 
ATOM   5667  C CG2 . ILE B 1 271 ? 107.651 78.355  102.743 1.00 24.17 ? 250  ILE B CG2 1 
ATOM   5668  C CD1 . ILE B 1 271 ? 108.065 75.399  103.794 1.00 24.17 ? 250  ILE B CD1 1 
ATOM   5669  N N   . MET B 1 272 ? 108.336 77.986  99.169  1.00 24.99 ? 251  MET B N   1 
ATOM   5670  C CA  . MET B 1 272 ? 107.809 78.882  98.146  1.00 24.99 ? 251  MET B CA  1 
ATOM   5671  C C   . MET B 1 272 ? 106.938 78.125  97.154  1.00 24.99 ? 251  MET B C   1 
ATOM   5672  O O   . MET B 1 272 ? 105.876 78.614  96.752  1.00 24.99 ? 251  MET B O   1 
ATOM   5673  C CB  . MET B 1 272 ? 108.950 79.595  97.422  1.00 24.99 ? 251  MET B CB  1 
ATOM   5674  C CG  . MET B 1 272 ? 109.719 80.551  98.307  1.00 24.99 ? 251  MET B CG  1 
ATOM   5675  S SD  . MET B 1 272 ? 111.117 81.344  97.500  1.00 24.99 ? 251  MET B SD  1 
ATOM   5676  C CE  . MET B 1 272 ? 110.293 82.458  96.372  1.00 24.99 ? 251  MET B CE  1 
ATOM   5677  N N   . GLN B 1 273 ? 107.364 76.924  96.759  1.00 26.81 ? 252  GLN B N   1 
ATOM   5678  C CA  . GLN B 1 273 ? 106.540 76.106  95.877  1.00 26.81 ? 252  GLN B CA  1 
ATOM   5679  C C   . GLN B 1 273 ? 105.223 75.736  96.544  1.00 26.81 ? 252  GLN B C   1 
ATOM   5680  O O   . GLN B 1 273 ? 104.160 75.814  95.918  1.00 26.81 ? 252  GLN B O   1 
ATOM   5681  C CB  . GLN B 1 273 ? 107.298 74.847  95.465  1.00 26.81 ? 252  GLN B CB  1 
ATOM   5682  C CG  . GLN B 1 273 ? 108.549 75.104  94.647  1.00 26.81 ? 252  GLN B CG  1 
ATOM   5683  C CD  . GLN B 1 273 ? 108.902 73.937  93.743  1.00 26.81 ? 252  GLN B CD  1 
ATOM   5684  O OE1 . GLN B 1 273 ? 108.211 72.919  93.725  1.00 26.81 ? 252  GLN B OE1 1 
ATOM   5685  N NE2 . GLN B 1 273 ? 109.988 74.079  92.992  1.00 26.81 ? 252  GLN B NE2 1 
ATOM   5686  N N   . TYR B 1 274 ? 105.272 75.335  97.817  1.00 24.70 ? 253  TYR B N   1 
ATOM   5687  C CA  . TYR B 1 274 ? 104.055 74.916  98.504  1.00 24.70 ? 253  TYR B CA  1 
ATOM   5688  C C   . TYR B 1 274 ? 103.077 76.068  98.682  1.00 24.70 ? 253  TYR B C   1 
ATOM   5689  O O   . TYR B 1 274 ? 101.861 75.862  98.605  1.00 24.70 ? 253  TYR B O   1 
ATOM   5690  C CB  . TYR B 1 274 ? 104.400 74.305  99.859  1.00 24.70 ? 253  TYR B CB  1 
ATOM   5691  C CG  . TYR B 1 274 ? 105.177 73.016  99.766  1.00 24.70 ? 253  TYR B CG  1 
ATOM   5692  C CD1 . TYR B 1 274 ? 105.063 72.194  98.655  1.00 24.70 ? 253  TYR B CD1 1 
ATOM   5693  C CD2 . TYR B 1 274 ? 106.015 72.614  100.796 1.00 24.70 ? 253  TYR B CD2 1 
ATOM   5694  C CE1 . TYR B 1 274 ? 105.769 71.010  98.567  1.00 24.70 ? 253  TYR B CE1 1 
ATOM   5695  C CE2 . TYR B 1 274 ? 106.730 71.436  100.716 1.00 24.70 ? 253  TYR B CE2 1 
ATOM   5696  C CZ  . TYR B 1 274 ? 106.600 70.636  99.600  1.00 24.70 ? 253  TYR B CZ  1 
ATOM   5697  O OH  . TYR B 1 274 ? 107.304 69.457  99.517  1.00 24.70 ? 253  TYR B OH  1 
ATOM   5698  N N   . ALA B 1 275 ? 103.576 77.276  98.923  1.00 24.14 ? 254  ALA B N   1 
ATOM   5699  C CA  . ALA B 1 275 ? 102.714 78.426  99.145  1.00 24.14 ? 254  ALA B CA  1 
ATOM   5700  C C   . ALA B 1 275 ? 102.433 79.219  97.877  1.00 24.14 ? 254  ALA B C   1 
ATOM   5701  O O   . ALA B 1 275 ? 101.730 80.230  97.938  1.00 24.14 ? 254  ALA B O   1 
ATOM   5702  C CB  . ALA B 1 275 ? 103.324 79.342  100.207 1.00 24.14 ? 254  ALA B CB  1 
ATOM   5703  N N   . SER B 1 276 ? 102.960 78.792  96.733  1.00 27.42 ? 255  SER B N   1 
ATOM   5704  C CA  . SER B 1 276 ? 102.614 79.421  95.466  1.00 27.42 ? 255  SER B CA  1 
ATOM   5705  C C   . SER B 1 276 ? 101.309 78.894  94.872  1.00 27.42 ? 255  SER B C   1 
ATOM   5706  O O   . SER B 1 276 ? 101.052 79.127  93.685  1.00 27.42 ? 255  SER B O   1 
ATOM   5707  C CB  . SER B 1 276 ? 103.753 79.245  94.458  1.00 27.42 ? 255  SER B CB  1 
ATOM   5708  O OG  . SER B 1 276 ? 104.892 80.006  94.817  1.00 27.42 ? 255  SER B OG  1 
ATOM   5709  N N   . GLU B 1 277 ? 100.486 78.190  95.650  1.00 24.20 ? 256  GLU B N   1 
ATOM   5710  C CA  . GLU B 1 277 ? 99.173  77.753  95.191  1.00 24.20 ? 256  GLU B CA  1 
ATOM   5711  C C   . GLU B 1 277 ? 98.054  78.667  95.682  1.00 24.20 ? 256  GLU B C   1 
ATOM   5712  O O   . GLU B 1 277 ? 97.117  78.955  94.933  1.00 24.20 ? 256  GLU B O   1 
ATOM   5713  C CB  . GLU B 1 277 ? 98.892  76.305  95.622  1.00 24.20 ? 256  GLU B CB  1 
ATOM   5714  C CG  . GLU B 1 277 ? 98.773  76.087  97.122  1.00 24.20 ? 256  GLU B CG  1 
ATOM   5715  C CD  . GLU B 1 277 ? 98.555  74.631  97.490  1.00 24.20 ? 256  GLU B CD  1 
ATOM   5716  O OE1 . GLU B 1 277 ? 98.518  73.781  96.577  1.00 24.20 ? 256  GLU B OE1 1 
ATOM   5717  O OE2 . GLU B 1 277 ? 98.414  74.337  98.694  1.00 24.20 ? 256  GLU B OE2 1 
ATOM   5718  N N   . ASN B 1 278 ? 98.128  79.133  96.927  1.00 22.17 ? 257  ASN B N   1 
ATOM   5719  C CA  . ASN B 1 278 ? 97.148  80.069  97.457  1.00 22.17 ? 257  ASN B CA  1 
ATOM   5720  C C   . ASN B 1 278 ? 97.618  81.513  97.355  1.00 22.17 ? 257  ASN B C   1 
ATOM   5721  O O   . ASN B 1 278 ? 97.002  82.399  97.957  1.00 22.17 ? 257  ASN B O   1 
ATOM   5722  C CB  . ASN B 1 278 ? 96.805  79.728  98.909  1.00 22.17 ? 257  ASN B CB  1 
ATOM   5723  C CG  . ASN B 1 278 ? 96.423  78.274  99.095  1.00 22.17 ? 257  ASN B CG  1 
ATOM   5724  O OD1 . ASN B 1 278 ? 95.382  77.828  98.614  1.00 22.17 ? 257  ASN B OD1 1 
ATOM   5725  N ND2 . ASN B 1 278 ? 97.261  77.529  99.800  1.00 22.17 ? 257  ASN B ND2 1 
ATOM   5726  N N   . LEU B 1 279 ? 98.678  81.766  96.588  1.00 20.79 ? 258  LEU B N   1 
ATOM   5727  C CA  . LEU B 1 279 ? 99.248  83.101  96.424  1.00 20.79 ? 258  LEU B CA  1 
ATOM   5728  C C   . LEU B 1 279 ? 99.476  83.751  97.787  1.00 20.79 ? 258  LEU B C   1 
ATOM   5729  O O   . LEU B 1 279 ? 98.874  84.765  98.140  1.00 20.79 ? 258  LEU B O   1 
ATOM   5730  C CB  . LEU B 1 279 ? 98.358  83.968  95.532  1.00 20.79 ? 258  LEU B CB  1 
ATOM   5731  C CG  . LEU B 1 279 ? 97.776  83.246  94.319  1.00 20.79 ? 258  LEU B CG  1 
ATOM   5732  C CD1 . LEU B 1 279 ? 96.742  84.106  93.632  1.00 20.79 ? 258  LEU B CD1 1 
ATOM   5733  C CD2 . LEU B 1 279 ? 98.887  82.867  93.358  1.00 20.79 ? 258  LEU B CD2 1 
ATOM   5734  N N   . ILE B 1 280 ? 100.354 83.126  98.555  1.00 15.86 ? 259  ILE B N   1 
ATOM   5735  C CA  . ILE B 1 280 ? 100.572 83.446  99.962  1.00 15.86 ? 259  ILE B CA  1 
ATOM   5736  C C   . ILE B 1 280 ? 101.949 84.082  100.095 1.00 15.86 ? 259  ILE B C   1 
ATOM   5737  O O   . ILE B 1 280 ? 102.916 83.553  99.539  1.00 15.86 ? 259  ILE B O   1 
ATOM   5738  C CB  . ILE B 1 280 ? 100.461 82.190  100.847 1.00 15.86 ? 259  ILE B CB  1 
ATOM   5739  C CG1 . ILE B 1 280 ? 98.996  81.846  101.097 1.00 15.86 ? 259  ILE B CG1 1 
ATOM   5740  C CG2 . ILE B 1 280 ? 101.173 82.380  102.165 1.00 15.86 ? 259  ILE B CG2 1 
ATOM   5741  C CD1 . ILE B 1 280 ? 98.805  80.543  101.828 1.00 15.86 ? 259  ILE B CD1 1 
ATOM   5742  N N   . PRO B 1 281 ? 102.077 85.216  100.785 1.00 12.38 ? 260  PRO B N   1 
ATOM   5743  C CA  . PRO B 1 281 ? 103.406 85.783  101.042 1.00 12.38 ? 260  PRO B CA  1 
ATOM   5744  C C   . PRO B 1 281 ? 104.278 84.827  101.844 1.00 12.38 ? 260  PRO B C   1 
ATOM   5745  O O   . PRO B 1 281 ? 103.807 84.112  102.728 1.00 12.38 ? 260  PRO B O   1 
ATOM   5746  C CB  . PRO B 1 281 ? 103.098 87.059  101.831 1.00 12.38 ? 260  PRO B CB  1 
ATOM   5747  C CG  . PRO B 1 281 ? 101.711 87.418  101.432 1.00 12.38 ? 260  PRO B CG  1 
ATOM   5748  C CD  . PRO B 1 281 ? 100.996 86.125  101.200 1.00 12.38 ? 260  PRO B CD  1 
ATOM   5749  N N   . VAL B 1 282 ? 105.572 84.828  101.525 1.00 14.09 ? 261  VAL B N   1 
ATOM   5750  C CA  . VAL B 1 282 ? 106.461 83.746  101.939 1.00 14.09 ? 261  VAL B CA  1 
ATOM   5751  C C   . VAL B 1 282 ? 107.739 84.235  102.606 1.00 14.09 ? 261  VAL B C   1 
ATOM   5752  O O   . VAL B 1 282 ? 108.787 83.610  102.425 1.00 14.09 ? 261  VAL B O   1 
ATOM   5753  C CB  . VAL B 1 282 ? 106.827 82.860  100.735 1.00 14.09 ? 261  VAL B CB  1 
ATOM   5754  C CG1 . VAL B 1 282 ? 105.648 82.027  100.306 1.00 14.09 ? 261  VAL B CG1 1 
ATOM   5755  C CG2 . VAL B 1 282 ? 107.320 83.717  99.585  1.00 14.09 ? 261  VAL B CG2 1 
ATOM   5756  N N   . THR B 1 283 ? 107.681 85.341  103.355 1.00 15.77 ? 262  THR B N   1 
ATOM   5757  C CA  . THR B 1 283 ? 108.891 85.984  103.873 1.00 15.77 ? 262  THR B CA  1 
ATOM   5758  C C   . THR B 1 283 ? 109.907 84.962  104.375 1.00 15.77 ? 262  THR B C   1 
ATOM   5759  O O   . THR B 1 283 ? 109.565 84.020  105.096 1.00 15.77 ? 262  THR B O   1 
ATOM   5760  C CB  . THR B 1 283 ? 108.549 86.974  104.991 1.00 15.77 ? 262  THR B CB  1 
ATOM   5761  O OG1 . THR B 1 283 ? 109.728 87.704  105.350 1.00 15.77 ? 262  THR B OG1 1 
ATOM   5762  C CG2 . THR B 1 283 ? 108.039 86.266  106.226 1.00 15.77 ? 262  THR B CG2 1 
ATOM   5763  N N   . LEU B 1 284 ? 111.148 85.118  103.934 1.00 18.56 ? 263  LEU B N   1 
ATOM   5764  C CA  . LEU B 1 284 ? 112.188 84.131  104.167 1.00 18.56 ? 263  LEU B CA  1 
ATOM   5765  C C   . LEU B 1 284 ? 113.369 84.757  104.896 1.00 18.56 ? 263  LEU B C   1 
ATOM   5766  O O   . LEU B 1 284 ? 113.422 85.965  105.138 1.00 18.56 ? 263  LEU B O   1 
ATOM   5767  C CB  . LEU B 1 284 ? 112.661 83.512  102.849 1.00 18.56 ? 263  LEU B CB  1 
ATOM   5768  C CG  . LEU B 1 284 ? 111.674 82.660  102.056 1.00 18.56 ? 263  LEU B CG  1 
ATOM   5769  C CD1 . LEU B 1 284 ? 112.256 82.300  100.708 1.00 18.56 ? 263  LEU B CD1 1 
ATOM   5770  C CD2 . LEU B 1 284 ? 111.287 81.412  102.827 1.00 18.56 ? 263  LEU B CD2 1 
ATOM   5771  N N   . GLU B 1 285 ? 114.309 83.892  105.265 1.00 20.06 ? 264  GLU B N   1 
ATOM   5772  C CA  . GLU B 1 285 ? 115.650 84.302  105.666 1.00 20.06 ? 264  GLU B CA  1 
ATOM   5773  C C   . GLU B 1 285 ? 116.520 83.063  105.507 1.00 20.06 ? 264  GLU B C   1 
ATOM   5774  O O   . GLU B 1 285 ? 116.381 82.114  106.283 1.00 20.06 ? 264  GLU B O   1 
ATOM   5775  C CB  . GLU B 1 285 ? 115.654 84.823  107.099 1.00 20.06 ? 264  GLU B CB  1 
ATOM   5776  C CG  . GLU B 1 285 ? 117.010 85.271  107.613 1.00 20.06 ? 264  GLU B CG  1 
ATOM   5777  C CD  . GLU B 1 285 ? 117.048 85.370  109.126 1.00 20.06 ? 264  GLU B CD  1 
ATOM   5778  O OE1 . GLU B 1 285 ? 115.981 85.248  109.761 1.00 20.06 ? 264  GLU B OE1 1 
ATOM   5779  O OE2 . GLU B 1 285 ? 118.147 85.563  109.681 1.00 20.06 ? 264  GLU B OE2 1 
ATOM   5780  N N   . LEU B 1 286 ? 117.408 83.064  104.515 1.00 21.61 ? 265  LEU B N   1 
ATOM   5781  C CA  . LEU B 1 286 ? 118.067 81.832  104.076 1.00 21.61 ? 265  LEU B CA  1 
ATOM   5782  C C   . LEU B 1 286 ? 119.580 81.993  104.113 1.00 21.61 ? 265  LEU B C   1 
ATOM   5783  O O   . LEU B 1 286 ? 120.205 82.301  103.099 1.00 21.61 ? 265  LEU B O   1 
ATOM   5784  C CB  . LEU B 1 286 ? 117.596 81.459  102.690 1.00 21.61 ? 265  LEU B CB  1 
ATOM   5785  C CG  . LEU B 1 286 ? 116.106 81.187  102.523 1.00 21.61 ? 265  LEU B CG  1 
ATOM   5786  C CD1 . LEU B 1 286 ? 115.762 81.073  101.057 1.00 21.61 ? 265  LEU B CD1 1 
ATOM   5787  C CD2 . LEU B 1 286 ? 115.733 79.927  103.253 1.00 21.61 ? 265  LEU B CD2 1 
ATOM   5788  N N   . GLY B 1 287 ? 120.163 81.739  105.281 1.00 21.19 ? 266  GLY B N   1 
ATOM   5789  C CA  . GLY B 1 287 ? 121.602 81.652  105.442 1.00 21.19 ? 266  GLY B CA  1 
ATOM   5790  C C   . GLY B 1 287 ? 122.405 82.801  104.869 1.00 21.19 ? 266  GLY B C   1 
ATOM   5791  O O   . GLY B 1 287 ? 121.866 83.871  104.576 1.00 21.19 ? 266  GLY B O   1 
ATOM   5792  N N   . GLY B 1 288 ? 123.701 82.578  104.687 1.00 21.92 ? 267  GLY B N   1 
ATOM   5793  C CA  . GLY B 1 288 ? 124.569 83.600  104.145 1.00 21.92 ? 267  GLY B CA  1 
ATOM   5794  C C   . GLY B 1 288 ? 126.028 83.342  104.444 1.00 21.92 ? 267  GLY B C   1 
ATOM   5795  O O   . GLY B 1 288 ? 126.364 82.743  105.469 1.00 21.92 ? 267  GLY B O   1 
ATOM   5796  N N   . LYS B 1 289 ? 126.903 83.789  103.557 1.00 16.02 ? 268  LYS B N   1 
ATOM   5797  C CA  . LYS B 1 289 ? 128.341 83.608  103.699 1.00 16.02 ? 268  LYS B CA  1 
ATOM   5798  C C   . LYS B 1 289 ? 128.965 85.001  103.779 1.00 16.02 ? 268  LYS B C   1 
ATOM   5799  O O   . LYS B 1 289 ? 129.390 85.569  102.773 1.00 16.02 ? 268  LYS B O   1 
ATOM   5800  C CB  . LYS B 1 289 ? 128.881 82.791  102.539 1.00 16.02 ? 268  LYS B CB  1 
ATOM   5801  C CG  . LYS B 1 289 ? 130.340 82.480  102.639 1.00 16.02 ? 268  LYS B CG  1 
ATOM   5802  C CD  . LYS B 1 289 ? 130.684 81.915  103.990 1.00 16.02 ? 268  LYS B CD  1 
ATOM   5803  C CE  . LYS B 1 289 ? 130.236 80.482  104.131 1.00 16.02 ? 268  LYS B CE  1 
ATOM   5804  N NZ  . LYS B 1 289 ? 130.607 79.942  105.465 1.00 16.02 ? 268  LYS B NZ  1 
ATOM   5805  N N   . SER B 1 290 ? 129.026 85.541  104.992 1.00 11.05 ? 269  SER B N   1 
ATOM   5806  C CA  . SER B 1 290 ? 129.341 86.948  105.220 1.00 11.05 ? 269  SER B CA  1 
ATOM   5807  C C   . SER B 1 290 ? 130.843 87.151  105.369 1.00 11.05 ? 269  SER B C   1 
ATOM   5808  O O   . SER B 1 290 ? 131.476 86.462  106.174 1.00 11.05 ? 269  SER B O   1 
ATOM   5809  C CB  . SER B 1 290 ? 128.631 87.451  106.461 1.00 11.05 ? 269  SER B CB  1 
ATOM   5810  O OG  . SER B 1 290 ? 127.276 87.046  106.447 1.00 11.05 ? 269  SER B OG  1 
ATOM   5811  N N   . PRO B 1 291 ? 131.444 88.065  104.617 1.00 7.21  ? 270  PRO B N   1 
ATOM   5812  C CA  . PRO B 1 291 ? 132.868 88.357  104.781 1.00 7.21  ? 270  PRO B CA  1 
ATOM   5813  C C   . PRO B 1 291 ? 133.128 89.390  105.873 1.00 7.21  ? 270  PRO B C   1 
ATOM   5814  O O   . PRO B 1 291 ? 132.223 90.052  106.377 1.00 7.21  ? 270  PRO B O   1 
ATOM   5815  C CB  . PRO B 1 291 ? 133.268 88.904  103.407 1.00 7.21  ? 270  PRO B CB  1 
ATOM   5816  C CG  . PRO B 1 291 ? 132.031 89.472  102.863 1.00 7.21  ? 270  PRO B CG  1 
ATOM   5817  C CD  . PRO B 1 291 ? 130.893 88.667  103.395 1.00 7.21  ? 270  PRO B CD  1 
ATOM   5818  N N   . ASN B 1 292 ? 134.404 89.501  106.233 1.00 6.23  ? 271  ASN B N   1 
ATOM   5819  C CA  . ASN B 1 292 ? 134.861 90.386  107.301 1.00 6.23  ? 271  ASN B CA  1 
ATOM   5820  C C   . ASN B 1 292 ? 136.196 90.975  106.867 1.00 6.23  ? 271  ASN B C   1 
ATOM   5821  O O   . ASN B 1 292 ? 137.207 90.274  106.886 1.00 6.23  ? 271  ASN B O   1 
ATOM   5822  C CB  . ASN B 1 292 ? 134.998 89.612  108.609 1.00 6.23  ? 271  ASN B CB  1 
ATOM   5823  C CG  . ASN B 1 292 ? 134.597 90.417  109.811 1.00 6.23  ? 271  ASN B CG  1 
ATOM   5824  O OD1 . ASN B 1 292 ? 134.216 91.576  109.697 1.00 6.23  ? 271  ASN B OD1 1 
ATOM   5825  N ND2 . ASN B 1 292 ? 134.679 89.805  110.980 1.00 6.23  ? 271  ASN B ND2 1 
ATOM   5826  N N   . ILE B 1 293 ? 136.209 92.249  106.471 1.00 5.54  ? 272  ILE B N   1 
ATOM   5827  C CA  . ILE B 1 293 ? 137.335 92.852  105.762 1.00 5.54  ? 272  ILE B CA  1 
ATOM   5828  C C   . ILE B 1 293 ? 138.135 93.733  106.714 1.00 5.54  ? 272  ILE B C   1 
ATOM   5829  O O   . ILE B 1 293 ? 137.563 94.451  107.539 1.00 5.54  ? 272  ILE B O   1 
ATOM   5830  C CB  . ILE B 1 293 ? 136.868 93.670  104.542 1.00 5.54  ? 272  ILE B CB  1 
ATOM   5831  C CG1 . ILE B 1 293 ? 136.057 92.815  103.573 1.00 5.54  ? 272  ILE B CG1 1 
ATOM   5832  C CG2 . ILE B 1 293 ? 138.048 94.225  103.795 1.00 5.54  ? 272  ILE B CG2 1 
ATOM   5833  C CD1 . ILE B 1 293 ? 134.562 92.875  103.790 1.00 5.54  ? 272  ILE B CD1 1 
ATOM   5834  N N   . PHE B 1 294 ? 139.464 93.681  106.586 1.00 7.15  ? 273  PHE B N   1 
ATOM   5835  C CA  . PHE B 1 294 ? 140.392 94.487  107.377 1.00 7.15  ? 273  PHE B CA  1 
ATOM   5836  C C   . PHE B 1 294 ? 141.348 95.208  106.434 1.00 7.15  ? 273  PHE B C   1 
ATOM   5837  O O   . PHE B 1 294 ? 142.031 94.562  105.634 1.00 7.15  ? 273  PHE B O   1 
ATOM   5838  C CB  . PHE B 1 294 ? 141.160 93.607  108.368 1.00 7.15  ? 273  PHE B CB  1 
ATOM   5839  C CG  . PHE B 1 294 ? 140.270 92.776  109.251 1.00 7.15  ? 273  PHE B CG  1 
ATOM   5840  C CD1 . PHE B 1 294 ? 139.848 91.523  108.853 1.00 7.15  ? 273  PHE B CD1 1 
ATOM   5841  C CD2 . PHE B 1 294 ? 139.844 93.256  110.473 1.00 7.15  ? 273  PHE B CD2 1 
ATOM   5842  C CE1 . PHE B 1 294 ? 139.022 90.768  109.660 1.00 7.15  ? 273  PHE B CE1 1 
ATOM   5843  C CE2 . PHE B 1 294 ? 139.019 92.502  111.280 1.00 7.15  ? 273  PHE B CE2 1 
ATOM   5844  C CZ  . PHE B 1 294 ? 138.610 91.259  110.873 1.00 7.15  ? 273  PHE B CZ  1 
ATOM   5845  N N   . PHE B 1 295 ? 141.420 96.537  106.544 1.00 8.24  ? 274  PHE B N   1 
ATOM   5846  C CA  . PHE B 1 295 ? 142.020 97.387  105.517 1.00 8.24  ? 274  PHE B CA  1 
ATOM   5847  C C   . PHE B 1 295 ? 143.416 97.908  105.835 1.00 8.24  ? 274  PHE B C   1 
ATOM   5848  O O   . PHE B 1 295 ? 143.893 98.796  105.123 1.00 8.24  ? 274  PHE B O   1 
ATOM   5849  C CB  . PHE B 1 295 ? 141.115 98.582  105.224 1.00 8.24  ? 274  PHE B CB  1 
ATOM   5850  C CG  . PHE B 1 295 ? 139.919 98.237  104.424 1.00 8.24  ? 274  PHE B CG  1 
ATOM   5851  C CD1 . PHE B 1 295 ? 140.012 98.138  103.054 1.00 8.24  ? 274  PHE B CD1 1 
ATOM   5852  C CD2 . PHE B 1 295 ? 138.709 97.998  105.032 1.00 8.24  ? 274  PHE B CD2 1 
ATOM   5853  C CE1 . PHE B 1 295 ? 138.928 97.813  102.309 1.00 8.24  ? 274  PHE B CE1 1 
ATOM   5854  C CE2 . PHE B 1 295 ? 137.619 97.677  104.288 1.00 8.24  ? 274  PHE B CE2 1 
ATOM   5855  C CZ  . PHE B 1 295 ? 137.735 97.578  102.925 1.00 8.24  ? 274  PHE B CZ  1 
ATOM   5856  N N   . ALA B 1 296 ? 144.072 97.403  106.873 1.00 11.48 ? 275  ALA B N   1 
ATOM   5857  C CA  . ALA B 1 296 ? 145.390 97.827  107.354 1.00 11.48 ? 275  ALA B CA  1 
ATOM   5858  C C   . ALA B 1 296 ? 145.323 99.145  108.105 1.00 11.48 ? 275  ALA B C   1 
ATOM   5859  O O   . ALA B 1 296 ? 146.345 99.582  108.641 1.00 11.48 ? 275  ALA B O   1 
ATOM   5860  C CB  . ALA B 1 296 ? 146.445 97.952  106.243 1.00 11.48 ? 275  ALA B CB  1 
ATOM   5861  N N   . ASP B 1 297 ? 144.167 99.793  108.170 1.00 11.80 ? 276  ASP B N   1 
ATOM   5862  C CA  . ASP B 1 297 ? 144.001 100.935 109.051 1.00 11.80 ? 276  ASP B CA  1 
ATOM   5863  C C   . ASP B 1 297 ? 143.885 100.514 110.507 1.00 11.80 ? 276  ASP B C   1 
ATOM   5864  O O   . ASP B 1 297 ? 144.070 101.351 111.397 1.00 11.80 ? 276  ASP B O   1 
ATOM   5865  C CB  . ASP B 1 297 ? 142.759 101.728 108.645 1.00 11.80 ? 276  ASP B CB  1 
ATOM   5866  C CG  . ASP B 1 297 ? 142.849 102.264 107.235 1.00 11.80 ? 276  ASP B CG  1 
ATOM   5867  O OD1 . ASP B 1 297 ? 143.019 103.490 107.071 1.00 11.80 ? 276  ASP B OD1 1 
ATOM   5868  O OD2 . ASP B 1 297 ? 142.762 101.458 106.288 1.00 11.80 ? 276  ASP B OD2 1 
ATOM   5869  N N   . VAL B 1 298 ? 143.575 99.242  110.761 1.00 11.86 ? 277  VAL B N   1 
ATOM   5870  C CA  . VAL B 1 298 ? 143.489 98.745  112.129 1.00 11.86 ? 277  VAL B CA  1 
ATOM   5871  C C   . VAL B 1 298 ? 144.873 98.675  112.761 1.00 11.86 ? 277  VAL B C   1 
ATOM   5872  O O   . VAL B 1 298 ? 145.065 99.074  113.915 1.00 11.86 ? 277  VAL B O   1 
ATOM   5873  C CB  . VAL B 1 298 ? 142.777 97.379  112.149 1.00 11.86 ? 277  VAL B CB  1 
ATOM   5874  C CG1 . VAL B 1 298 ? 141.295 97.556  111.902 1.00 11.86 ? 277  VAL B CG1 1 
ATOM   5875  C CG2 . VAL B 1 298 ? 143.361 96.457  111.092 1.00 11.86 ? 277  VAL B CG2 1 
ATOM   5876  N N   . ALA B 1 299 ? 145.858 98.176  112.017 1.00 16.25 ? 278  ALA B N   1 
ATOM   5877  C CA  . ALA B 1 299 ? 147.229 98.058  112.511 1.00 16.25 ? 278  ALA B CA  1 
ATOM   5878  C C   . ALA B 1 299 ? 147.976 99.365  112.249 1.00 16.25 ? 278  ALA B C   1 
ATOM   5879  O O   . ALA B 1 299 ? 148.890 99.458  111.429 1.00 16.25 ? 278  ALA B O   1 
ATOM   5880  C CB  . ALA B 1 299 ? 147.926 96.868  111.866 1.00 16.25 ? 278  ALA B CB  1 
ATOM   5881  N N   . ARG B 1 300 ? 147.550 100.399 112.970 1.00 17.70 ? 279  ARG B N   1 
ATOM   5882  C CA  . ARG B 1 300 ? 148.186 101.705 112.894 1.00 17.70 ? 279  ARG B CA  1 
ATOM   5883  C C   . ARG B 1 300 ? 148.705 102.209 114.228 1.00 17.70 ? 279  ARG B C   1 
ATOM   5884  O O   . ARG B 1 300 ? 149.574 103.089 114.235 1.00 17.70 ? 279  ARG B O   1 
ATOM   5885  C CB  . ARG B 1 300 ? 147.210 102.742 112.320 1.00 17.70 ? 279  ARG B CB  1 
ATOM   5886  C CG  . ARG B 1 300 ? 147.871 103.873 111.563 1.00 17.70 ? 279  ARG B CG  1 
ATOM   5887  C CD  . ARG B 1 300 ? 146.833 104.704 110.840 1.00 17.70 ? 279  ARG B CD  1 
ATOM   5888  N NE  . ARG B 1 300 ? 146.035 105.493 111.771 1.00 17.70 ? 279  ARG B NE  1 
ATOM   5889  C CZ  . ARG B 1 300 ? 144.948 106.176 111.430 1.00 17.70 ? 279  ARG B CZ  1 
ATOM   5890  N NH1 . ARG B 1 300 ? 144.527 106.170 110.175 1.00 17.70 ? 279  ARG B NH1 1 
ATOM   5891  N NH2 . ARG B 1 300 ? 144.283 106.865 112.345 1.00 17.70 ? 279  ARG B NH2 1 
ATOM   5892  N N   . GLU B 1 301 ? 148.206 101.700 115.350 1.00 26.95 ? 280  GLU B N   1 
ATOM   5893  C CA  . GLU B 1 301 ? 148.730 102.083 116.655 1.00 26.95 ? 280  GLU B CA  1 
ATOM   5894  C C   . GLU B 1 301 ? 148.913 100.916 117.615 1.00 26.95 ? 280  GLU B C   1 
ATOM   5895  O O   . GLU B 1 301 ? 149.597 101.088 118.631 1.00 26.95 ? 280  GLU B O   1 
ATOM   5896  C CB  . GLU B 1 301 ? 147.812 103.135 117.294 1.00 26.95 ? 280  GLU B CB  1 
ATOM   5897  C CG  . GLU B 1 301 ? 148.392 103.866 118.491 1.00 26.95 ? 280  GLU B CG  1 
ATOM   5898  C CD  . GLU B 1 301 ? 147.542 105.044 118.908 1.00 26.95 ? 280  GLU B CD  1 
ATOM   5899  O OE1 . GLU B 1 301 ? 146.488 105.266 118.278 1.00 26.95 ? 280  GLU B OE1 1 
ATOM   5900  O OE2 . GLU B 1 301 ? 147.929 105.750 119.862 1.00 26.95 ? 280  GLU B OE2 1 
ATOM   5901  N N   . ASP B 1 302 ? 148.365 99.731  117.323 1.00 26.29 ? 281  ASP B N   1 
ATOM   5902  C CA  . ASP B 1 302 ? 148.300 98.615  118.271 1.00 26.29 ? 281  ASP B CA  1 
ATOM   5903  C C   . ASP B 1 302 ? 147.520 99.011  119.521 1.00 26.29 ? 281  ASP B C   1 
ATOM   5904  O O   . ASP B 1 302 ? 147.825 98.579  120.634 1.00 26.29 ? 281  ASP B O   1 
ATOM   5905  C CB  . ASP B 1 302 ? 149.692 98.098  118.639 1.00 26.29 ? 281  ASP B CB  1 
ATOM   5906  C CG  . ASP B 1 302 ? 150.369 97.387  117.491 1.00 26.29 ? 281  ASP B CG  1 
ATOM   5907  O OD1 . ASP B 1 302 ? 149.655 96.908  116.586 1.00 26.29 ? 281  ASP B OD1 1 
ATOM   5908  O OD2 . ASP B 1 302 ? 151.616 97.311  117.493 1.00 26.29 ? 281  ASP B OD2 1 
ATOM   5909  N N   . ASP B 1 303 ? 146.504 99.837  119.331 1.00 20.06 ? 282  ASP B N   1 
ATOM   5910  C CA  . ASP B 1 303 ? 145.702 100.380 120.410 1.00 20.06 ? 282  ASP B CA  1 
ATOM   5911  C C   . ASP B 1 303 ? 144.417 99.572  120.594 1.00 20.06 ? 282  ASP B C   1 
ATOM   5912  O O   . ASP B 1 303 ? 144.252 98.463  120.062 1.00 20.06 ? 282  ASP B O   1 
ATOM   5913  C CB  . ASP B 1 303 ? 145.408 101.857 120.144 1.00 20.06 ? 282  ASP B CB  1 
ATOM   5914  C CG  . ASP B 1 303 ? 144.591 102.071 118.892 1.00 20.06 ? 282  ASP B CG  1 
ATOM   5915  O OD1 . ASP B 1 303 ? 145.036 101.632 117.813 1.00 20.06 ? 282  ASP B OD1 1 
ATOM   5916  O OD2 . ASP B 1 303 ? 143.506 102.680 118.986 1.00 20.06 ? 282  ASP B OD2 1 
ATOM   5917  N N   . ASP B 1 304 ? 143.500 100.131 121.385 1.00 16.01 ? 283  ASP B N   1 
ATOM   5918  C CA  . ASP B 1 304 ? 142.232 99.467  121.653 1.00 16.01 ? 283  ASP B CA  1 
ATOM   5919  C C   . ASP B 1 304 ? 141.460 99.169  120.376 1.00 16.01 ? 283  ASP B C   1 
ATOM   5920  O O   . ASP B 1 304 ? 140.682 98.213  120.339 1.00 16.01 ? 283  ASP B O   1 
ATOM   5921  C CB  . ASP B 1 304 ? 141.391 100.318 122.603 1.00 16.01 ? 283  ASP B CB  1 
ATOM   5922  C CG  . ASP B 1 304 ? 141.381 101.787 122.223 1.00 16.01 ? 283  ASP B CG  1 
ATOM   5923  O OD1 . ASP B 1 304 ? 141.341 102.098 121.015 1.00 16.01 ? 283  ASP B OD1 1 
ATOM   5924  O OD2 . ASP B 1 304 ? 141.411 102.636 123.137 1.00 16.01 ? 283  ASP B OD2 1 
ATOM   5925  N N   . PHE B 1 305 ? 141.662 99.951  119.316 1.00 12.86 ? 284  PHE B N   1 
ATOM   5926  C CA  . PHE B 1 305 ? 140.971 99.642  118.070 1.00 12.86 ? 284  PHE B CA  1 
ATOM   5927  C C   . PHE B 1 305 ? 141.520 98.373  117.435 1.00 12.86 ? 284  PHE B C   1 
ATOM   5928  O O   . PHE B 1 305 ? 140.758 97.560  116.902 1.00 12.86 ? 284  PHE B O   1 
ATOM   5929  C CB  . PHE B 1 305 ? 141.064 100.803 117.089 1.00 12.86 ? 284  PHE B CB  1 
ATOM   5930  C CG  . PHE B 1 305 ? 140.149 100.653 115.915 1.00 12.86 ? 284  PHE B CG  1 
ATOM   5931  C CD1 . PHE B 1 305 ? 138.806 100.941 116.037 1.00 12.86 ? 284  PHE B CD1 1 
ATOM   5932  C CD2 . PHE B 1 305 ? 140.619 100.189 114.707 1.00 12.86 ? 284  PHE B CD2 1 
ATOM   5933  C CE1 . PHE B 1 305 ? 137.961 100.791 114.974 1.00 12.86 ? 284  PHE B CE1 1 
ATOM   5934  C CE2 . PHE B 1 305 ? 139.775 100.037 113.643 1.00 12.86 ? 284  PHE B CE2 1 
ATOM   5935  C CZ  . PHE B 1 305 ? 138.448 100.337 113.774 1.00 12.86 ? 284  PHE B CZ  1 
ATOM   5936  N N   . PHE B 1 306 ? 142.840 98.189  117.467 1.00 13.63 ? 285  PHE B N   1 
ATOM   5937  C CA  . PHE B 1 306 ? 143.408 96.932  116.995 1.00 13.63 ? 285  PHE B CA  1 
ATOM   5938  C C   . PHE B 1 306 ? 142.935 95.772  117.856 1.00 13.63 ? 285  PHE B C   1 
ATOM   5939  O O   . PHE B 1 306 ? 142.681 94.672  117.349 1.00 13.63 ? 285  PHE B O   1 
ATOM   5940  C CB  . PHE B 1 306 ? 144.931 97.013  116.988 1.00 13.63 ? 285  PHE B CB  1 
ATOM   5941  C CG  . PHE B 1 306 ? 145.589 95.920  116.203 1.00 13.63 ? 285  PHE B CG  1 
ATOM   5942  C CD1 . PHE B 1 306 ? 145.006 95.432  115.053 1.00 13.63 ? 285  PHE B CD1 1 
ATOM   5943  C CD2 . PHE B 1 306 ? 146.798 95.392  116.607 1.00 13.63 ? 285  PHE B CD2 1 
ATOM   5944  C CE1 . PHE B 1 306 ? 145.614 94.434  114.328 1.00 13.63 ? 285  PHE B CE1 1 
ATOM   5945  C CE2 . PHE B 1 306 ? 147.408 94.394  115.883 1.00 13.63 ? 285  PHE B CE2 1 
ATOM   5946  C CZ  . PHE B 1 306 ? 146.816 93.915  114.744 1.00 13.63 ? 285  PHE B CZ  1 
ATOM   5947  N N   . ASP B 1 307 ? 142.795 96.004  119.163 1.00 14.38 ? 286  ASP B N   1 
ATOM   5948  C CA  . ASP B 1 307 ? 142.249 94.966  120.031 1.00 14.38 ? 286  ASP B CA  1 
ATOM   5949  C C   . ASP B 1 307 ? 140.817 94.616  119.642 1.00 14.38 ? 286  ASP B C   1 
ATOM   5950  O O   . ASP B 1 307 ? 140.436 93.439  119.630 1.00 14.38 ? 286  ASP B O   1 
ATOM   5951  C CB  . ASP B 1 307 ? 142.318 95.416  121.488 1.00 14.38 ? 286  ASP B CB  1 
ATOM   5952  C CG  . ASP B 1 307 ? 142.453 94.255  122.446 1.00 14.38 ? 286  ASP B CG  1 
ATOM   5953  O OD1 . ASP B 1 307 ? 141.880 93.183  122.164 1.00 14.38 ? 286  ASP B OD1 1 
ATOM   5954  O OD2 . ASP B 1 307 ? 143.133 94.414  123.481 1.00 14.38 ? 286  ASP B OD2 1 
ATOM   5955  N N   . LYS B 1 308 ? 140.009 95.627  119.320 1.00 10.97 ? 287  LYS B N   1 
ATOM   5956  C CA  . LYS B 1 308 ? 138.626 95.383  118.919 1.00 10.97 ? 287  LYS B CA  1 
ATOM   5957  C C   . LYS B 1 308 ? 138.553 94.651  117.587 1.00 10.97 ? 287  LYS B C   1 
ATOM   5958  O O   . LYS B 1 308 ? 137.675 93.808  117.388 1.00 10.97 ? 287  LYS B O   1 
ATOM   5959  C CB  . LYS B 1 308 ? 137.857 96.698  118.841 1.00 10.97 ? 287  LYS B CB  1 
ATOM   5960  C CG  . LYS B 1 308 ? 136.374 96.508  118.634 1.00 10.97 ? 287  LYS B CG  1 
ATOM   5961  C CD  . LYS B 1 308 ? 135.630 97.818  118.704 1.00 10.97 ? 287  LYS B CD  1 
ATOM   5962  C CE  . LYS B 1 308 ? 134.136 97.593  118.668 1.00 10.97 ? 287  LYS B CE  1 
ATOM   5963  N NZ  . LYS B 1 308 ? 133.394 98.852  118.916 1.00 10.97 ? 287  LYS B NZ  1 
ATOM   5964  N N   . ALA B 1 309 ? 139.452 94.974  116.657 1.00 9.89  ? 288  ALA B N   1 
ATOM   5965  C CA  . ALA B 1 309 ? 139.501 94.242  115.395 1.00 9.89  ? 288  ALA B CA  1 
ATOM   5966  C C   . ALA B 1 309 ? 139.866 92.782  115.625 1.00 9.89  ? 288  ALA B C   1 
ATOM   5967  O O   . ALA B 1 309 ? 139.272 91.878  115.023 1.00 9.89  ? 288  ALA B O   1 
ATOM   5968  C CB  . ALA B 1 309 ? 140.497 94.901  114.445 1.00 9.89  ? 288  ALA B CB  1 
ATOM   5969  N N   . LEU B 1 310 ? 140.840 92.534  116.502 1.00 12.98 ? 289  LEU B N   1 
ATOM   5970  C CA  . LEU B 1 310 ? 141.199 91.164  116.848 1.00 12.98 ? 289  LEU B CA  1 
ATOM   5971  C C   . LEU B 1 310 ? 140.009 90.421  117.433 1.00 12.98 ? 289  LEU B C   1 
ATOM   5972  O O   . LEU B 1 310 ? 139.732 89.276  117.062 1.00 12.98 ? 289  LEU B O   1 
ATOM   5973  C CB  . LEU B 1 310 ? 142.358 91.167  117.839 1.00 12.98 ? 289  LEU B CB  1 
ATOM   5974  C CG  . LEU B 1 310 ? 143.746 91.375  117.255 1.00 12.98 ? 289  LEU B CG  1 
ATOM   5975  C CD1 . LEU B 1 310 ? 144.766 91.304  118.365 1.00 12.98 ? 289  LEU B CD1 1 
ATOM   5976  C CD2 . LEU B 1 310 ? 144.027 90.335  116.191 1.00 12.98 ? 289  LEU B CD2 1 
ATOM   5977  N N   . GLU B 1 311 ? 139.294 91.060  118.357 1.00 15.67 ? 290  GLU B N   1 
ATOM   5978  C CA  . GLU B 1 311 ? 138.134 90.417  118.963 1.00 15.67 ? 290  GLU B CA  1 
ATOM   5979  C C   . GLU B 1 311 ? 137.057 90.130  117.928 1.00 15.67 ? 290  GLU B C   1 
ATOM   5980  O O   . GLU B 1 311 ? 136.464 89.046  117.915 1.00 15.67 ? 290  GLU B O   1 
ATOM   5981  C CB  . GLU B 1 311 ? 137.576 91.288  120.080 1.00 15.67 ? 290  GLU B CB  1 
ATOM   5982  C CG  . GLU B 1 311 ? 136.322 90.733  120.705 1.00 15.67 ? 290  GLU B CG  1 
ATOM   5983  C CD  . GLU B 1 311 ? 135.524 91.794  121.414 1.00 15.67 ? 290  GLU B CD  1 
ATOM   5984  O OE1 . GLU B 1 311 ? 135.418 92.913  120.873 1.00 15.67 ? 290  GLU B OE1 1 
ATOM   5985  O OE2 . GLU B 1 311 ? 135.019 91.516  122.520 1.00 15.67 ? 290  GLU B OE2 1 
ATOM   5986  N N   . GLY B 1 312 ? 136.785 91.097  117.049 1.00 10.40 ? 291  GLY B N   1 
ATOM   5987  C CA  . GLY B 1 312 ? 135.781 90.913  116.021 1.00 10.40 ? 291  GLY B CA  1 
ATOM   5988  C C   . GLY B 1 312 ? 136.145 89.863  114.997 1.00 10.40 ? 291  GLY B C   1 
ATOM   5989  O O   . GLY B 1 312 ? 135.256 89.330  114.329 1.00 10.40 ? 291  GLY B O   1 
ATOM   5990  N N   . PHE B 1 313 ? 137.436 89.567  114.843 1.00 10.95 ? 292  PHE B N   1 
ATOM   5991  C CA  . PHE B 1 313 ? 137.828 88.462  113.973 1.00 10.95 ? 292  PHE B CA  1 
ATOM   5992  C C   . PHE B 1 313 ? 137.271 87.140  114.484 1.00 10.95 ? 292  PHE B C   1 
ATOM   5993  O O   . PHE B 1 313 ? 136.640 86.387  113.736 1.00 10.95 ? 292  PHE B O   1 
ATOM   5994  C CB  . PHE B 1 313 ? 139.350 88.386  113.859 1.00 10.95 ? 292  PHE B CB  1 
ATOM   5995  C CG  . PHE B 1 313 ? 139.841 87.125  113.210 1.00 10.95 ? 292  PHE B CG  1 
ATOM   5996  C CD1 . PHE B 1 313 ? 140.094 85.990  113.960 1.00 10.95 ? 292  PHE B CD1 1 
ATOM   5997  C CD2 . PHE B 1 313 ? 140.042 87.072  111.847 1.00 10.95 ? 292  PHE B CD2 1 
ATOM   5998  C CE1 . PHE B 1 313 ? 140.530 84.833  113.359 1.00 10.95 ? 292  PHE B CE1 1 
ATOM   5999  C CE2 . PHE B 1 313 ? 140.483 85.917  111.247 1.00 10.95 ? 292  PHE B CE2 1 
ATOM   6000  C CZ  . PHE B 1 313 ? 140.727 84.797  112.004 1.00 10.95 ? 292  PHE B CZ  1 
ATOM   6001  N N   . THR B 1 314 ? 137.497 86.841  115.763 1.00 12.17 ? 293  THR B N   1 
ATOM   6002  C CA  . THR B 1 314 ? 137.134 85.557  116.352 1.00 12.17 ? 293  THR B CA  1 
ATOM   6003  C C   . THR B 1 314 ? 135.637 85.383  116.537 1.00 12.17 ? 293  THR B C   1 
ATOM   6004  O O   . THR B 1 314 ? 135.227 84.394  117.149 1.00 12.17 ? 293  THR B O   1 
ATOM   6005  C CB  . THR B 1 314 ? 137.827 85.383  117.703 1.00 12.17 ? 293  THR B CB  1 
ATOM   6006  O OG1 . THR B 1 314 ? 137.106 86.108  118.704 1.00 12.17 ? 293  THR B OG1 1 
ATOM   6007  C CG2 . THR B 1 314 ? 139.242 85.915  117.643 1.00 12.17 ? 293  THR B CG2 1 
ATOM   6008  N N   . MET B 1 315 ? 134.816 86.299  116.027 1.00 13.33 ? 294  MET B N   1 
ATOM   6009  C CA  . MET B 1 315 ? 133.378 86.253  116.257 1.00 13.33 ? 294  MET B CA  1 
ATOM   6010  C C   . MET B 1 315 ? 132.692 85.115  115.514 1.00 13.33 ? 294  MET B C   1 
ATOM   6011  O O   . MET B 1 315 ? 131.491 84.911  115.711 1.00 13.33 ? 294  MET B O   1 
ATOM   6012  C CB  . MET B 1 315 ? 132.751 87.591  115.866 1.00 13.33 ? 294  MET B CB  1 
ATOM   6013  C CG  . MET B 1 315 ? 131.479 87.932  116.616 1.00 13.33 ? 294  MET B CG  1 
ATOM   6014  S SD  . MET B 1 315 ? 131.771 88.534  118.282 1.00 13.33 ? 294  MET B SD  1 
ATOM   6015  C CE  . MET B 1 315 ? 133.126 89.658  117.996 1.00 13.33 ? 294  MET B CE  1 
ATOM   6016  N N   . PHE B 1 316 ? 133.411 84.381  114.660 1.00 14.06 ? 295  PHE B N   1 
ATOM   6017  C CA  . PHE B 1 316 ? 132.828 83.195  114.044 1.00 14.06 ? 295  PHE B CA  1 
ATOM   6018  C C   . PHE B 1 316 ? 132.448 82.159  115.090 1.00 14.06 ? 295  PHE B C   1 
ATOM   6019  O O   . PHE B 1 316 ? 131.481 81.415  114.905 1.00 14.06 ? 295  PHE B O   1 
ATOM   6020  C CB  . PHE B 1 316 ? 133.796 82.592  113.024 1.00 14.06 ? 295  PHE B CB  1 
ATOM   6021  C CG  . PHE B 1 316 ? 135.074 82.071  113.625 1.00 14.06 ? 295  PHE B CG  1 
ATOM   6022  C CD1 . PHE B 1 316 ? 135.150 80.786  114.130 1.00 14.06 ? 295  PHE B CD1 1 
ATOM   6023  C CD2 . PHE B 1 316 ? 136.200 82.868  113.683 1.00 14.06 ? 295  PHE B CD2 1 
ATOM   6024  C CE1 . PHE B 1 316 ? 136.315 80.311  114.679 1.00 14.06 ? 295  PHE B CE1 1 
ATOM   6025  C CE2 . PHE B 1 316 ? 137.368 82.393  114.231 1.00 14.06 ? 295  PHE B CE2 1 
ATOM   6026  C CZ  . PHE B 1 316 ? 137.423 81.113  114.728 1.00 14.06 ? 295  PHE B CZ  1 
ATOM   6027  N N   . ALA B 1 317 ? 133.191 82.098  116.191 1.00 14.31 ? 296  ALA B N   1 
ATOM   6028  C CA  . ALA B 1 317 ? 132.911 81.152  117.259 1.00 14.31 ? 296  ALA B CA  1 
ATOM   6029  C C   . ALA B 1 317 ? 131.641 81.481  118.019 1.00 14.31 ? 296  ALA B C   1 
ATOM   6030  O O   . ALA B 1 317 ? 131.218 80.676  118.850 1.00 14.31 ? 296  ALA B O   1 
ATOM   6031  C CB  . ALA B 1 317 ? 134.091 81.094  118.229 1.00 14.31 ? 296  ALA B CB  1 
ATOM   6032  N N   . LEU B 1 318 ? 131.031 82.634  117.774 1.00 13.74 ? 297  LEU B N   1 
ATOM   6033  C CA  . LEU B 1 318 ? 129.813 83.003  118.482 1.00 13.74 ? 297  LEU B CA  1 
ATOM   6034  C C   . LEU B 1 318 ? 128.661 82.119  118.021 1.00 13.74 ? 297  LEU B C   1 
ATOM   6035  O O   . LEU B 1 318 ? 128.355 82.063  116.825 1.00 13.74 ? 297  LEU B O   1 
ATOM   6036  C CB  . LEU B 1 318 ? 129.492 84.471  118.240 1.00 13.74 ? 297  LEU B CB  1 
ATOM   6037  C CG  . LEU B 1 318 ? 128.258 84.975  118.973 1.00 13.74 ? 297  LEU B CG  1 
ATOM   6038  C CD1 . LEU B 1 318 ? 128.620 85.381  120.394 1.00 13.74 ? 297  LEU B CD1 1 
ATOM   6039  C CD2 . LEU B 1 318 ? 127.629 86.123  118.217 1.00 13.74 ? 297  LEU B CD2 1 
ATOM   6040  N N   . ASN B 1 319 ? 128.019 81.440  118.973 1.00 15.35 ? 298  ASN B N   1 
ATOM   6041  C CA  . ASN B 1 319 ? 126.961 80.473  118.685 1.00 15.35 ? 298  ASN B CA  1 
ATOM   6042  C C   . ASN B 1 319 ? 127.450 79.408  117.708 1.00 15.35 ? 298  ASN B C   1 
ATOM   6043  O O   . ASN B 1 319 ? 126.774 79.060  116.740 1.00 15.35 ? 298  ASN B O   1 
ATOM   6044  C CB  . ASN B 1 319 ? 125.702 81.167  118.159 1.00 15.35 ? 298  ASN B CB  1 
ATOM   6045  C CG  . ASN B 1 319 ? 124.513 80.235  118.078 1.00 15.35 ? 298  ASN B CG  1 
ATOM   6046  O OD1 . ASN B 1 319 ? 124.097 79.655  119.078 1.00 15.35 ? 298  ASN B OD1 1 
ATOM   6047  N ND2 . ASN B 1 319 ? 123.960 80.085  116.882 1.00 15.35 ? 298  ASN B ND2 1 
ATOM   6048  N N   . GLN B 1 320 ? 128.662 78.914  117.956 1.00 16.19 ? 299  GLN B N   1 
ATOM   6049  C CA  . GLN B 1 320 ? 129.245 77.792  117.219 1.00 16.19 ? 299  GLN B CA  1 
ATOM   6050  C C   . GLN B 1 320 ? 129.213 78.006  115.714 1.00 16.19 ? 299  GLN B C   1 
ATOM   6051  O O   . GLN B 1 320 ? 129.233 77.042  114.947 1.00 16.19 ? 299  GLN B O   1 
ATOM   6052  C CB  . GLN B 1 320 ? 128.546 76.473  117.565 1.00 16.19 ? 299  GLN B CB  1 
ATOM   6053  C CG  . GLN B 1 320 ? 128.620 76.084  119.017 1.00 16.19 ? 299  GLN B CG  1 
ATOM   6054  C CD  . GLN B 1 320 ? 127.703 76.912  119.880 1.00 16.19 ? 299  GLN B CD  1 
ATOM   6055  O OE1 . GLN B 1 320 ? 128.143 77.562  120.823 1.00 16.19 ? 299  GLN B OE1 1 
ATOM   6056  N NE2 . GLN B 1 320 ? 126.421 76.911  119.551 1.00 16.19 ? 299  GLN B NE2 1 
ATOM   6057  N N   . GLY B 1 321 ? 129.139 79.254  115.268 1.00 14.40 ? 300  GLY B N   1 
ATOM   6058  C CA  . GLY B 1 321 ? 129.122 79.525  113.852 1.00 14.40 ? 300  GLY B CA  1 
ATOM   6059  C C   . GLY B 1 321 ? 127.836 79.174  113.143 1.00 14.40 ? 300  GLY B C   1 
ATOM   6060  O O   . GLY B 1 321 ? 127.750 79.375  111.927 1.00 14.40 ? 300  GLY B O   1 
ATOM   6061  N N   . GLU B 1 322 ? 126.833 78.666  113.852 1.00 16.83 ? 301  GLU B N   1 
ATOM   6062  C CA  . GLU B 1 322 ? 125.537 78.389  113.239 1.00 16.83 ? 301  GLU B CA  1 
ATOM   6063  C C   . GLU B 1 322 ? 124.623 79.601  113.341 1.00 16.83 ? 301  GLU B C   1 
ATOM   6064  O O   . GLU B 1 322 ? 123.473 79.531  113.762 1.00 16.83 ? 301  GLU B O   1 
ATOM   6065  C CB  . GLU B 1 322 ? 124.902 77.154  113.870 1.00 16.83 ? 301  GLU B CB  1 
ATOM   6066  C CG  . GLU B 1 322 ? 124.651 77.239  115.362 1.00 16.83 ? 301  GLU B CG  1 
ATOM   6067  C CD  . GLU B 1 322 ? 124.582 75.880  116.015 1.00 16.83 ? 301  GLU B CD  1 
ATOM   6068  O OE1 . GLU B 1 322 ? 125.049 74.903  115.399 1.00 16.83 ? 301  GLU B OE1 1 
ATOM   6069  O OE2 . GLU B 1 322 ? 124.060 75.789  117.143 1.00 16.83 ? 301  GLU B OE2 1 
ATOM   6070  N N   . VAL B 1 323 ? 125.157 80.741  112.928 1.00 15.56 ? 302  VAL B N   1 
ATOM   6071  C CA  . VAL B 1 323 ? 124.395 81.970  112.784 1.00 15.56 ? 302  VAL B CA  1 
ATOM   6072  C C   . VAL B 1 323 ? 124.342 82.295  111.302 1.00 15.56 ? 302  VAL B C   1 
ATOM   6073  O O   . VAL B 1 323 ? 125.312 82.070  110.571 1.00 15.56 ? 302  VAL B O   1 
ATOM   6074  C CB  . VAL B 1 323 ? 125.007 83.135  113.587 1.00 15.56 ? 302  VAL B CB  1 
ATOM   6075  C CG1 . VAL B 1 323 ? 124.021 84.282  113.695 1.00 15.56 ? 302  VAL B CG1 1 
ATOM   6076  C CG2 . VAL B 1 323 ? 125.416 82.671  114.962 1.00 15.56 ? 302  VAL B CG2 1 
ATOM   6077  N N   . CYS B 1 324 ? 123.193 82.798  110.860 1.00 18.61 ? 303  CYS B N   1 
ATOM   6078  C CA  . CYS B 1 324 ? 123.011 83.126  109.452 1.00 18.61 ? 303  CYS B CA  1 
ATOM   6079  C C   . CYS B 1 324 ? 124.059 84.124  108.967 1.00 18.61 ? 303  CYS B C   1 
ATOM   6080  O O   . CYS B 1 324 ? 124.538 84.028  107.833 1.00 18.61 ? 303  CYS B O   1 
ATOM   6081  C CB  . CYS B 1 324 ? 121.594 83.655  109.247 1.00 18.61 ? 303  CYS B CB  1 
ATOM   6082  S SG  . CYS B 1 324 ? 121.260 85.206  110.114 1.00 18.61 ? 303  CYS B SG  1 
ATOM   6083  N N   . THR B 1 325 ? 124.431 85.086  109.813 1.00 14.73 ? 304  THR B N   1 
ATOM   6084  C CA  . THR B 1 325 ? 125.494 86.042  109.505 1.00 14.73 ? 304  THR B CA  1 
ATOM   6085  C C   . THR B 1 325 ? 126.776 85.585  110.194 1.00 14.73 ? 304  THR B C   1 
ATOM   6086  O O   . THR B 1 325 ? 127.164 86.086  111.248 1.00 14.73 ? 304  THR B O   1 
ATOM   6087  C CB  . THR B 1 325 ? 125.107 87.445  109.944 1.00 14.73 ? 304  THR B CB  1 
ATOM   6088  O OG1 . THR B 1 325 ? 124.398 87.371  111.185 1.00 14.73 ? 304  THR B OG1 1 
ATOM   6089  C CG2 . THR B 1 325 ? 124.235 88.105  108.910 1.00 14.73 ? 304  THR B CG2 1 
ATOM   6090  N N   . CYS B 1 326 ? 127.433 84.618  109.586 1.00 14.18 ? 305  CYS B N   1 
ATOM   6091  C CA  . CYS B 1 326 ? 128.690 84.146  110.142 1.00 14.18 ? 305  CYS B CA  1 
ATOM   6092  C C   . CYS B 1 326 ? 129.848 84.760  109.378 1.00 14.18 ? 305  CYS B C   1 
ATOM   6093  O O   . CYS B 1 326 ? 129.817 84.793  108.141 1.00 14.18 ? 305  CYS B O   1 
ATOM   6094  C CB  . CYS B 1 326 ? 128.773 82.624  110.077 1.00 14.18 ? 305  CYS B CB  1 
ATOM   6095  S SG  . CYS B 1 326 ? 130.087 81.904  111.092 1.00 14.18 ? 305  CYS B SG  1 
ATOM   6096  N N   . PRO B 1 327 ? 130.874 85.241  110.064 1.00 11.59 ? 306  PRO B N   1 
ATOM   6097  C CA  . PRO B 1 327 ? 131.985 85.913  109.380 1.00 11.59 ? 306  PRO B CA  1 
ATOM   6098  C C   . PRO B 1 327 ? 132.923 84.946  108.682 1.00 11.59 ? 306  PRO B C   1 
ATOM   6099  O O   . PRO B 1 327 ? 134.065 85.306  108.390 1.00 11.59 ? 306  PRO B O   1 
ATOM   6100  C CB  . PRO B 1 327 ? 132.712 86.643  110.516 1.00 11.59 ? 306  PRO B CB  1 
ATOM   6101  C CG  . PRO B 1 327 ? 132.248 85.989  111.753 1.00 11.59 ? 306  PRO B CG  1 
ATOM   6102  C CD  . PRO B 1 327 ? 130.863 85.530  111.503 1.00 11.59 ? 306  PRO B CD  1 
ATOM   6103  N N   . SER B 1 328 ? 132.472 83.719  108.429 1.00 12.07 ? 307  SER B N   1 
ATOM   6104  C CA  . SER B 1 328 ? 133.347 82.616  108.042 1.00 12.07 ? 307  SER B CA  1 
ATOM   6105  C C   . SER B 1 328 ? 134.273 82.911  106.863 1.00 12.07 ? 307  SER B C   1 
ATOM   6106  O O   . SER B 1 328 ? 135.186 82.127  106.588 1.00 12.07 ? 307  SER B O   1 
ATOM   6107  C CB  . SER B 1 328 ? 132.504 81.377  107.742 1.00 12.07 ? 307  SER B CB  1 
ATOM   6108  O OG  . SER B 1 328 ? 131.387 81.703  106.940 1.00 12.07 ? 307  SER B OG  1 
ATOM   6109  N N   . ARG B 1 329 ? 134.059 84.014  106.153 1.00 11.14 ? 308  ARG B N   1 
ATOM   6110  C CA  . ARG B 1 329 ? 135.039 84.518  105.199 1.00 11.14 ? 308  ARG B CA  1 
ATOM   6111  C C   . ARG B 1 329 ? 135.707 85.758  105.779 1.00 11.14 ? 308  ARG B C   1 
ATOM   6112  O O   . ARG B 1 329 ? 135.024 86.690  106.208 1.00 11.14 ? 308  ARG B O   1 
ATOM   6113  C CB  . ARG B 1 329 ? 134.393 84.851  103.855 1.00 11.14 ? 308  ARG B CB  1 
ATOM   6114  C CG  . ARG B 1 329 ? 133.767 83.671  103.151 1.00 11.14 ? 308  ARG B CG  1 
ATOM   6115  C CD  . ARG B 1 329 ? 133.483 83.993  101.696 1.00 11.14 ? 308  ARG B CD  1 
ATOM   6116  N NE  . ARG B 1 329 ? 132.399 84.957  101.540 1.00 11.14 ? 308  ARG B NE  1 
ATOM   6117  C CZ  . ARG B 1 329 ? 132.399 85.938  100.644 1.00 11.14 ? 308  ARG B CZ  1 
ATOM   6118  N NH1 . ARG B 1 329 ? 133.425 86.085  99.819  1.00 11.14 ? 308  ARG B NH1 1 
ATOM   6119  N NH2 . ARG B 1 329 ? 131.373 86.771  100.572 1.00 11.14 ? 308  ARG B NH2 1 
ATOM   6120  N N   . VAL B 1 330 ? 137.037 85.773  105.792 1.00 9.67  ? 309  VAL B N   1 
ATOM   6121  C CA  . VAL B 1 330 ? 137.792 86.898  106.332 1.00 9.67  ? 309  VAL B CA  1 
ATOM   6122  C C   . VAL B 1 330 ? 138.757 87.409  105.276 1.00 9.67  ? 309  VAL B C   1 
ATOM   6123  O O   . VAL B 1 330 ? 139.533 86.636  104.706 1.00 9.67  ? 309  VAL B O   1 
ATOM   6124  C CB  . VAL B 1 330 ? 138.536 86.529  107.627 1.00 9.67  ? 309  VAL B CB  1 
ATOM   6125  C CG1 . VAL B 1 330 ? 139.494 87.622  108.006 1.00 9.67  ? 309  VAL B CG1 1 
ATOM   6126  C CG2 . VAL B 1 330 ? 137.540 86.373  108.740 1.00 9.67  ? 309  VAL B CG2 1 
ATOM   6127  N N   . LEU B 1 331 ? 138.700 88.712  105.024 1.00 9.85  ? 310  LEU B N   1 
ATOM   6128  C CA  . LEU B 1 331 ? 139.538 89.405  104.058 1.00 9.85  ? 310  LEU B CA  1 
ATOM   6129  C C   . LEU B 1 331 ? 140.438 90.355  104.827 1.00 9.85  ? 310  LEU B C   1 
ATOM   6130  O O   . LEU B 1 331 ? 139.949 91.217  105.560 1.00 9.85  ? 310  LEU B O   1 
ATOM   6131  C CB  . LEU B 1 331 ? 138.677 90.172  103.058 1.00 9.85  ? 310  LEU B CB  1 
ATOM   6132  C CG  . LEU B 1 331 ? 137.761 89.282  102.236 1.00 9.85  ? 310  LEU B CG  1 
ATOM   6133  C CD1 . LEU B 1 331 ? 136.726 90.090  101.500 1.00 9.85  ? 310  LEU B CD1 1 
ATOM   6134  C CD2 . LEU B 1 331 ? 138.623 88.550  101.268 1.00 9.85  ? 310  LEU B CD2 1 
ATOM   6135  N N   . ILE B 1 332 ? 141.744 90.195  104.675 1.00 12.00 ? 311  ILE B N   1 
ATOM   6136  C CA  . ILE B 1 332 ? 142.714 90.996  105.406 1.00 12.00 ? 311  ILE B CA  1 
ATOM   6137  C C   . ILE B 1 332 ? 143.646 91.658  104.409 1.00 12.00 ? 311  ILE B C   1 
ATOM   6138  O O   . ILE B 1 332 ? 144.090 91.023  103.447 1.00 12.00 ? 311  ILE B O   1 
ATOM   6139  C CB  . ILE B 1 332 ? 143.496 90.143  106.418 1.00 12.00 ? 311  ILE B CB  1 
ATOM   6140  C CG1 . ILE B 1 332 ? 142.529 89.566  107.437 1.00 12.00 ? 311  ILE B CG1 1 
ATOM   6141  C CG2 . ILE B 1 332 ? 144.532 90.966  107.141 1.00 12.00 ? 311  ILE B CG2 1 
ATOM   6142  C CD1 . ILE B 1 332 ? 143.187 88.726  108.439 1.00 12.00 ? 311  ILE B CD1 1 
ATOM   6143  N N   . GLN B 1 333 ? 143.921 92.940  104.628 1.00 14.04 ? 312  GLN B N   1 
ATOM   6144  C CA  . GLN B 1 333 ? 144.807 93.664  103.732 1.00 14.04 ? 312  GLN B CA  1 
ATOM   6145  C C   . GLN B 1 333 ? 146.156 92.964  103.666 1.00 14.04 ? 312  GLN B C   1 
ATOM   6146  O O   . GLN B 1 333 ? 146.664 92.466  104.673 1.00 14.04 ? 312  GLN B O   1 
ATOM   6147  C CB  . GLN B 1 333 ? 144.971 95.111  104.200 1.00 14.04 ? 312  GLN B CB  1 
ATOM   6148  C CG  . GLN B 1 333 ? 145.825 96.037  103.312 1.00 14.04 ? 312  GLN B CG  1 
ATOM   6149  C CD  . GLN B 1 333 ? 145.411 96.116  101.842 1.00 14.04 ? 312  GLN B CD  1 
ATOM   6150  O OE1 . GLN B 1 333 ? 144.883 95.172  101.261 1.00 14.04 ? 312  GLN B OE1 1 
ATOM   6151  N NE2 . GLN B 1 333 ? 145.660 97.268  101.237 1.00 14.04 ? 312  GLN B NE2 1 
ATOM   6152  N N   . GLU B 1 334 ? 146.727 92.917  102.462 1.00 18.50 ? 313  GLU B N   1 
ATOM   6153  C CA  . GLU B 1 334 ? 147.937 92.139  102.223 1.00 18.50 ? 313  GLU B CA  1 
ATOM   6154  C C   . GLU B 1 334 ? 149.107 92.594  103.082 1.00 18.50 ? 313  GLU B C   1 
ATOM   6155  O O   . GLU B 1 334 ? 150.060 91.829  103.263 1.00 18.50 ? 313  GLU B O   1 
ATOM   6156  C CB  . GLU B 1 334 ? 148.312 92.217  100.743 1.00 18.50 ? 313  GLU B CB  1 
ATOM   6157  C CG  . GLU B 1 334 ? 149.209 91.096  100.254 1.00 18.50 ? 313  GLU B CG  1 
ATOM   6158  C CD  . GLU B 1 334 ? 149.851 91.409  98.912  1.00 18.50 ? 313  GLU B CD  1 
ATOM   6159  O OE1 . GLU B 1 334 ? 150.954 91.996  98.896  1.00 18.50 ? 313  GLU B OE1 1 
ATOM   6160  O OE2 . GLU B 1 334 ? 149.252 91.061  97.874  1.00 18.50 ? 313  GLU B OE2 1 
ATOM   6161  N N   . SER B 1 335 ? 149.063 93.813  103.613 1.00 15.85 ? 314  SER B N   1 
ATOM   6162  C CA  . SER B 1 335 ? 150.162 94.344  104.405 1.00 15.85 ? 314  SER B CA  1 
ATOM   6163  C C   . SER B 1 335 ? 150.092 93.972  105.881 1.00 15.85 ? 314  SER B C   1 
ATOM   6164  O O   . SER B 1 335 ? 151.095 94.127  106.584 1.00 15.85 ? 314  SER B O   1 
ATOM   6165  C CB  . SER B 1 335 ? 150.210 95.869  104.282 1.00 15.85 ? 314  SER B CB  1 
ATOM   6166  O OG  . SER B 1 335 ? 149.254 96.471  105.136 1.00 15.85 ? 314  SER B OG  1 
ATOM   6167  N N   . ILE B 1 336 ? 148.950 93.491  106.374 1.00 16.53 ? 315  ILE B N   1 
ATOM   6168  C CA  . ILE B 1 336 ? 148.811 93.202  107.799 1.00 16.53 ? 315  ILE B CA  1 
ATOM   6169  C C   . ILE B 1 336 ? 148.384 91.759  108.028 1.00 16.53 ? 315  ILE B C   1 
ATOM   6170  O O   . ILE B 1 336 ? 147.953 91.405  109.130 1.00 16.53 ? 315  ILE B O   1 
ATOM   6171  C CB  . ILE B 1 336 ? 147.802 94.145  108.476 1.00 16.53 ? 315  ILE B CB  1 
ATOM   6172  C CG1 . ILE B 1 336 ? 146.415 93.933  107.882 1.00 16.53 ? 315  ILE B CG1 1 
ATOM   6173  C CG2 . ILE B 1 336 ? 148.225 95.582  108.313 1.00 16.53 ? 315  ILE B CG2 1 
ATOM   6174  C CD1 . ILE B 1 336 ? 145.319 94.595  108.655 1.00 16.53 ? 315  ILE B CD1 1 
ATOM   6175  N N   . TYR B 1 337 ? 148.487 90.916  106.999 1.00 19.87 ? 316  TYR B N   1 
ATOM   6176  C CA  . TYR B 1 337 ? 148.054 89.531  107.155 1.00 19.87 ? 316  TYR B CA  1 
ATOM   6177  C C   . TYR B 1 337 ? 148.883 88.809  108.208 1.00 19.87 ? 316  TYR B C   1 
ATOM   6178  O O   . TYR B 1 337 ? 148.338 88.086  109.053 1.00 19.87 ? 316  TYR B O   1 
ATOM   6179  C CB  . TYR B 1 337 ? 148.126 88.801  105.813 1.00 19.87 ? 316  TYR B CB  1 
ATOM   6180  C CG  . TYR B 1 337 ? 148.313 87.307  105.938 1.00 19.87 ? 316  TYR B CG  1 
ATOM   6181  C CD1 . TYR B 1 337 ? 147.235 86.470  106.186 1.00 19.87 ? 316  TYR B CD1 1 
ATOM   6182  C CD2 . TYR B 1 337 ? 149.569 86.731  105.797 1.00 19.87 ? 316  TYR B CD2 1 
ATOM   6183  C CE1 . TYR B 1 337 ? 147.406 85.105  106.301 1.00 19.87 ? 316  TYR B CE1 1 
ATOM   6184  C CE2 . TYR B 1 337 ? 149.750 85.369  105.912 1.00 19.87 ? 316  TYR B CE2 1 
ATOM   6185  C CZ  . TYR B 1 337 ? 148.666 84.560  106.163 1.00 19.87 ? 316  TYR B CZ  1 
ATOM   6186  O OH  . TYR B 1 337 ? 148.850 83.201  106.275 1.00 19.87 ? 316  TYR B OH  1 
ATOM   6187  N N   . ASP B 1 338 ? 150.201 89.019  108.193 1.00 19.62 ? 317  ASP B N   1 
ATOM   6188  C CA  . ASP B 1 338 ? 151.084 88.309  109.112 1.00 19.62 ? 317  ASP B CA  1 
ATOM   6189  C C   . ASP B 1 338 ? 150.787 88.675  110.559 1.00 19.62 ? 317  ASP B C   1 
ATOM   6190  O O   . ASP B 1 338 ? 150.583 87.797  111.404 1.00 19.62 ? 317  ASP B O   1 
ATOM   6191  C CB  . ASP B 1 338 ? 152.539 88.620  108.770 1.00 19.62 ? 317  ASP B CB  1 
ATOM   6192  C CG  . ASP B 1 338 ? 152.964 88.021  107.447 1.00 19.62 ? 317  ASP B CG  1 
ATOM   6193  O OD1 . ASP B 1 338 ? 152.409 86.971  107.063 1.00 19.62 ? 317  ASP B OD1 1 
ATOM   6194  O OD2 . ASP B 1 338 ? 153.854 88.600  106.791 1.00 19.62 ? 317  ASP B OD2 1 
ATOM   6195  N N   . LYS B 1 339 ? 150.759 89.974  110.859 1.00 17.73 ? 318  LYS B N   1 
ATOM   6196  C CA  . LYS B 1 339 ? 150.520 90.428  112.226 1.00 17.73 ? 318  LYS B CA  1 
ATOM   6197  C C   . LYS B 1 339 ? 149.128 90.038  112.703 1.00 17.73 ? 318  LYS B C   1 
ATOM   6198  O O   . LYS B 1 339 ? 148.951 89.535  113.829 1.00 17.73 ? 318  LYS B O   1 
ATOM   6199  C CB  . LYS B 1 339 ? 150.718 91.941  112.281 1.00 17.73 ? 318  LYS B CB  1 
ATOM   6200  C CG  . LYS B 1 339 ? 150.438 92.596  113.611 1.00 17.73 ? 318  LYS B CG  1 
ATOM   6201  C CD  . LYS B 1 339 ? 150.435 94.103  113.432 1.00 17.73 ? 318  LYS B CD  1 
ATOM   6202  C CE  . LYS B 1 339 ? 151.166 94.807  114.557 1.00 17.73 ? 318  LYS B CE  1 
ATOM   6203  N NZ  . LYS B 1 339 ? 150.787 96.247  114.620 1.00 17.73 ? 318  LYS B NZ  1 
ATOM   6204  N N   . PHE B 1 340 ? 148.126 90.246  111.849 1.00 16.43 ? 319  PHE B N   1 
ATOM   6205  C CA  . PHE B 1 340 ? 146.757 89.951  112.240 1.00 16.43 ? 319  PHE B CA  1 
ATOM   6206  C C   . PHE B 1 340 ? 146.585 88.472  112.545 1.00 16.43 ? 319  PHE B C   1 
ATOM   6207  O O   . PHE B 1 340 ? 145.945 88.118  113.535 1.00 16.43 ? 319  PHE B O   1 
ATOM   6208  C CB  . PHE B 1 340 ? 145.784 90.397  111.153 1.00 16.43 ? 319  PHE B CB  1 
ATOM   6209  C CG  . PHE B 1 340 ? 144.433 90.763  111.678 1.00 16.43 ? 319  PHE B CG  1 
ATOM   6210  C CD1 . PHE B 1 340 ? 144.190 92.039  112.147 1.00 16.43 ? 319  PHE B CD1 1 
ATOM   6211  C CD2 . PHE B 1 340 ? 143.415 89.834  111.722 1.00 16.43 ? 319  PHE B CD2 1 
ATOM   6212  C CE1 . PHE B 1 340 ? 142.960 92.382  112.639 1.00 16.43 ? 319  PHE B CE1 1 
ATOM   6213  C CE2 . PHE B 1 340 ? 142.182 90.173  112.209 1.00 16.43 ? 319  PHE B CE2 1 
ATOM   6214  C CZ  . PHE B 1 340 ? 141.954 91.449  112.671 1.00 16.43 ? 319  PHE B CZ  1 
ATOM   6215  N N   . MET B 1 341 ? 147.153 87.591  111.715 1.00 19.08 ? 320  MET B N   1 
ATOM   6216  C CA  . MET B 1 341 ? 147.118 86.166  112.036 1.00 19.08 ? 320  MET B CA  1 
ATOM   6217  C C   . MET B 1 341 ? 147.906 85.829  113.292 1.00 19.08 ? 320  MET B C   1 
ATOM   6218  O O   . MET B 1 341 ? 147.413 85.086  114.147 1.00 19.08 ? 320  MET B O   1 
ATOM   6219  C CB  . MET B 1 341 ? 147.596 85.345  110.841 1.00 19.08 ? 320  MET B CB  1 
ATOM   6220  C CG  . MET B 1 341 ? 146.662 85.420  109.656 1.00 19.08 ? 320  MET B CG  1 
ATOM   6221  S SD  . MET B 1 341 ? 145.072 84.713  110.163 1.00 19.08 ? 320  MET B SD  1 
ATOM   6222  C CE  . MET B 1 341 ? 144.049 86.141  110.460 1.00 19.08 ? 320  MET B CE  1 
ATOM   6223  N N   . GLU B 1 342 ? 149.118 86.366  113.447 1.00 19.01 ? 321  GLU B N   1 
ATOM   6224  C CA  . GLU B 1 342 ? 149.908 85.951  114.600 1.00 19.01 ? 321  GLU B CA  1 
ATOM   6225  C C   . GLU B 1 342 ? 149.290 86.400  115.918 1.00 19.01 ? 321  GLU B C   1 
ATOM   6226  O O   . GLU B 1 342 ? 149.691 85.894  116.971 1.00 19.01 ? 321  GLU B O   1 
ATOM   6227  C CB  . GLU B 1 342 ? 151.361 86.431  114.485 1.00 19.01 ? 321  GLU B CB  1 
ATOM   6228  C CG  . GLU B 1 342 ? 151.601 87.925  114.423 1.00 19.01 ? 321  GLU B CG  1 
ATOM   6229  C CD  . GLU B 1 342 ? 151.689 88.583  115.787 1.00 19.01 ? 321  GLU B CD  1 
ATOM   6230  O OE1 . GLU B 1 342 ? 151.931 87.872  116.784 1.00 19.01 ? 321  GLU B OE1 1 
ATOM   6231  O OE2 . GLU B 1 342 ? 151.552 89.823  115.854 1.00 19.01 ? 321  GLU B OE2 1 
ATOM   6232  N N   . ARG B 1 343 ? 148.332 87.327  115.896 1.00 15.57 ? 322  ARG B N   1 
ATOM   6233  C CA  . ARG B 1 343 ? 147.574 87.586  117.122 1.00 15.57 ? 322  ARG B CA  1 
ATOM   6234  C C   . ARG B 1 343 ? 146.180 86.956  117.147 1.00 15.57 ? 322  ARG B C   1 
ATOM   6235  O O   . ARG B 1 343 ? 145.691 86.576  118.225 1.00 15.57 ? 322  ARG B O   1 
ATOM   6236  C CB  . ARG B 1 343 ? 147.465 89.091  117.363 1.00 15.57 ? 322  ARG B CB  1 
ATOM   6237  C CG  . ARG B 1 343 ? 148.798 89.781  117.256 1.00 15.57 ? 322  ARG B CG  1 
ATOM   6238  C CD  . ARG B 1 343 ? 148.695 91.252  117.543 1.00 15.57 ? 322  ARG B CD  1 
ATOM   6239  N NE  . ARG B 1 343 ? 148.021 91.508  118.808 1.00 15.57 ? 322  ARG B NE  1 
ATOM   6240  C CZ  . ARG B 1 343 ? 148.077 92.665  119.453 1.00 15.57 ? 322  ARG B CZ  1 
ATOM   6241  N NH1 . ARG B 1 343 ? 148.784 93.667  118.949 1.00 15.57 ? 322  ARG B NH1 1 
ATOM   6242  N NH2 . ARG B 1 343 ? 147.432 92.821  120.601 1.00 15.57 ? 322  ARG B NH2 1 
ATOM   6243  N N   . ALA B 1 344 ? 145.529 86.811  115.992 1.00 15.05 ? 323  ALA B N   1 
ATOM   6244  C CA  . ALA B 1 344 ? 144.191 86.240  115.956 1.00 15.05 ? 323  ALA B CA  1 
ATOM   6245  C C   . ALA B 1 344 ? 144.210 84.745  116.227 1.00 15.05 ? 323  ALA B C   1 
ATOM   6246  O O   . ALA B 1 344 ? 143.280 84.221  116.849 1.00 15.05 ? 323  ALA B O   1 
ATOM   6247  C CB  . ALA B 1 344 ? 143.538 86.528  114.607 1.00 15.05 ? 323  ALA B CB  1 
ATOM   6248  N N   . VAL B 1 345 ? 145.246 84.039  115.772 1.00 16.26 ? 324  VAL B N   1 
ATOM   6249  C CA  . VAL B 1 345 ? 145.370 82.628  116.115 1.00 16.26 ? 324  VAL B CA  1 
ATOM   6250  C C   . VAL B 1 345 ? 145.513 82.467  117.621 1.00 16.26 ? 324  VAL B C   1 
ATOM   6251  O O   . VAL B 1 345 ? 144.954 81.540  118.215 1.00 16.26 ? 324  VAL B O   1 
ATOM   6252  C CB  . VAL B 1 345 ? 146.542 81.985  115.353 1.00 16.26 ? 324  VAL B CB  1 
ATOM   6253  C CG1 . VAL B 1 345 ? 146.672 80.524  115.722 1.00 16.26 ? 324  VAL B CG1 1 
ATOM   6254  C CG2 . VAL B 1 345 ? 146.333 82.124  113.859 1.00 16.26 ? 324  VAL B CG2 1 
ATOM   6255  N N   . GLN B 1 346 ? 146.250 83.373  118.265 1.00 17.97 ? 325  GLN B N   1 
ATOM   6256  C CA  . GLN B 1 346 ? 146.354 83.336  119.720 1.00 17.97 ? 325  GLN B CA  1 
ATOM   6257  C C   . GLN B 1 346 ? 144.989 83.515  120.371 1.00 17.97 ? 325  GLN B C   1 
ATOM   6258  O O   . GLN B 1 346 ? 144.602 82.745  121.262 1.00 17.97 ? 325  GLN B O   1 
ATOM   6259  C CB  . GLN B 1 346 ? 147.317 84.418  120.206 1.00 17.97 ? 325  GLN B CB  1 
ATOM   6260  C CG  . GLN B 1 346 ? 148.774 83.997  120.239 1.00 17.97 ? 325  GLN B CG  1 
ATOM   6261  C CD  . GLN B 1 346 ? 149.710 85.184  120.341 1.00 17.97 ? 325  GLN B CD  1 
ATOM   6262  O OE1 . GLN B 1 346 ? 149.273 86.333  120.384 1.00 17.97 ? 325  GLN B OE1 1 
ATOM   6263  N NE2 . GLN B 1 346 ? 151.008 84.909  120.379 1.00 17.97 ? 325  GLN B NE2 1 
ATOM   6264  N N   . ARG B 1 347 ? 144.235 84.524  119.932 1.00 16.34 ? 326  ARG B N   1 
ATOM   6265  C CA  . ARG B 1 347 ? 142.937 84.755  120.564 1.00 16.34 ? 326  ARG B CA  1 
ATOM   6266  C C   . ARG B 1 347 ? 141.931 83.647  120.272 1.00 16.34 ? 326  ARG B C   1 
ATOM   6267  O O   . ARG B 1 347 ? 141.021 83.434  121.079 1.00 16.34 ? 326  ARG B O   1 
ATOM   6268  C CB  . ARG B 1 347 ? 142.363 86.104  120.144 1.00 16.34 ? 326  ARG B CB  1 
ATOM   6269  C CG  . ARG B 1 347 ? 143.020 87.267  120.844 1.00 16.34 ? 326  ARG B CG  1 
ATOM   6270  C CD  . ARG B 1 347 ? 142.552 88.574  120.274 1.00 16.34 ? 326  ARG B CD  1 
ATOM   6271  N NE  . ARG B 1 347 ? 141.279 88.972  120.857 1.00 16.34 ? 326  ARG B NE  1 
ATOM   6272  C CZ  . ARG B 1 347 ? 141.135 89.973  121.716 1.00 16.34 ? 326  ARG B CZ  1 
ATOM   6273  N NH1 . ARG B 1 347 ? 142.189 90.683  122.089 1.00 16.34 ? 326  ARG B NH1 1 
ATOM   6274  N NH2 . ARG B 1 347 ? 139.936 90.263  122.197 1.00 16.34 ? 326  ARG B NH2 1 
ATOM   6275  N N   . VAL B 1 348 ? 142.058 82.951  119.140 1.00 17.36 ? 327  VAL B N   1 
ATOM   6276  C CA  . VAL B 1 348 ? 141.223 81.778  118.894 1.00 17.36 ? 327  VAL B CA  1 
ATOM   6277  C C   . VAL B 1 348 ? 141.639 80.619  119.790 1.00 17.36 ? 327  VAL B C   1 
ATOM   6278  O O   . VAL B 1 348 ? 140.793 79.929  120.369 1.00 17.36 ? 327  VAL B O   1 
ATOM   6279  C CB  . VAL B 1 348 ? 141.260 81.385  117.409 1.00 17.36 ? 327  VAL B CB  1 
ATOM   6280  C CG1 . VAL B 1 348 ? 140.485 80.108  117.193 1.00 17.36 ? 327  VAL B CG1 1 
ATOM   6281  C CG2 . VAL B 1 348 ? 140.646 82.489  116.576 1.00 17.36 ? 327  VAL B CG2 1 
ATOM   6282  N N   . GLN B 1 349 ? 142.944 80.383  119.921 1.00 17.50 ? 328  GLN B N   1 
ATOM   6283  C CA  . GLN B 1 349 ? 143.417 79.335  120.813 1.00 17.50 ? 328  GLN B CA  1 
ATOM   6284  C C   . GLN B 1 349 ? 143.076 79.628  122.264 1.00 17.50 ? 328  GLN B C   1 
ATOM   6285  O O   . GLN B 1 349 ? 143.130 78.720  123.099 1.00 17.50 ? 328  GLN B O   1 
ATOM   6286  C CB  . GLN B 1 349 ? 144.923 79.153  120.649 1.00 17.50 ? 328  GLN B CB  1 
ATOM   6287  C CG  . GLN B 1 349 ? 145.319 78.599  119.296 1.00 17.50 ? 328  GLN B CG  1 
ATOM   6288  C CD  . GLN B 1 349 ? 146.810 78.660  119.059 1.00 17.50 ? 328  GLN B CD  1 
ATOM   6289  O OE1 . GLN B 1 349 ? 147.524 79.410  119.722 1.00 17.50 ? 328  GLN B OE1 1 
ATOM   6290  N NE2 . GLN B 1 349 ? 147.289 77.871  118.105 1.00 17.50 ? 328  GLN B NE2 1 
ATOM   6291  N N   . ALA B 1 350 ? 142.725 80.869  122.583 1.00 17.99 ? 329  ALA B N   1 
ATOM   6292  C CA  . ALA B 1 350 ? 142.280 81.209  123.925 1.00 17.99 ? 329  ALA B CA  1 
ATOM   6293  C C   . ALA B 1 350 ? 140.783 81.016  124.124 1.00 17.99 ? 329  ALA B C   1 
ATOM   6294  O O   . ALA B 1 350 ? 140.270 81.350  125.198 1.00 17.99 ? 329  ALA B O   1 
ATOM   6295  C CB  . ALA B 1 350 ? 142.659 82.654  124.257 1.00 17.99 ? 329  ALA B CB  1 
ATOM   6296  N N   . ILE B 1 351 ? 140.069 80.497  123.128 1.00 19.55 ? 330  ILE B N   1 
ATOM   6297  C CA  . ILE B 1 351 ? 138.631 80.267  123.253 1.00 19.55 ? 330  ILE B CA  1 
ATOM   6298  C C   . ILE B 1 351 ? 138.407 79.018  124.097 1.00 19.55 ? 330  ILE B C   1 
ATOM   6299  O O   . ILE B 1 351 ? 138.871 77.928  123.748 1.00 19.55 ? 330  ILE B O   1 
ATOM   6300  C CB  . ILE B 1 351 ? 137.967 80.127  121.876 1.00 19.55 ? 330  ILE B CB  1 
ATOM   6301  C CG1 . ILE B 1 351 ? 138.100 81.420  121.077 1.00 19.55 ? 330  ILE B CG1 1 
ATOM   6302  C CG2 . ILE B 1 351 ? 136.506 79.786  122.029 1.00 19.55 ? 330  ILE B CG2 1 
ATOM   6303  C CD1 . ILE B 1 351 ? 137.645 81.289  119.645 1.00 19.55 ? 330  ILE B CD1 1 
ATOM   6304  N N   . LYS B 1 352 ? 137.679 79.170  125.199 1.00 23.58 ? 331  LYS B N   1 
ATOM   6305  C CA  . LYS B 1 352 ? 137.496 78.093  126.163 1.00 23.58 ? 331  LYS B CA  1 
ATOM   6306  C C   . LYS B 1 352 ? 136.276 77.254  125.809 1.00 23.58 ? 331  LYS B C   1 
ATOM   6307  O O   . LYS B 1 352 ? 135.180 77.788  125.616 1.00 23.58 ? 331  LYS B O   1 
ATOM   6308  C CB  . LYS B 1 352 ? 137.349 78.654  127.575 1.00 23.58 ? 331  LYS B CB  1 
ATOM   6309  C CG  . LYS B 1 352 ? 137.015 77.610  128.620 1.00 23.58 ? 331  LYS B CG  1 
ATOM   6310  C CD  . LYS B 1 352 ? 137.524 78.020  129.994 1.00 23.58 ? 331  LYS B CD  1 
ATOM   6311  C CE  . LYS B 1 352 ? 137.429 76.867  130.972 1.00 23.58 ? 331  LYS B CE  1 
ATOM   6312  N NZ  . LYS B 1 352 ? 136.200 76.061  130.735 1.00 23.58 ? 331  LYS B NZ  1 
ATOM   6313  N N   . GLN B 1 353 ? 136.471 75.941  125.739 1.00 24.45 ? 332  GLN B N   1 
ATOM   6314  C CA  . GLN B 1 353 ? 135.405 74.993  125.466 1.00 24.45 ? 332  GLN B CA  1 
ATOM   6315  C C   . GLN B 1 353 ? 135.191 74.081  126.666 1.00 24.45 ? 332  GLN B C   1 
ATOM   6316  O O   . GLN B 1 353 ? 136.121 73.787  127.421 1.00 24.45 ? 332  GLN B O   1 
ATOM   6317  C CB  . GLN B 1 353 ? 135.719 74.149  124.231 1.00 24.45 ? 332  GLN B CB  1 
ATOM   6318  C CG  . GLN B 1 353 ? 134.491 73.559  123.571 1.00 24.45 ? 332  GLN B CG  1 
ATOM   6319  C CD  . GLN B 1 353 ? 134.745 73.169  122.137 1.00 24.45 ? 332  GLN B CD  1 
ATOM   6320  O OE1 . GLN B 1 353 ? 135.788 72.606  121.817 1.00 24.45 ? 332  GLN B OE1 1 
ATOM   6321  N NE2 . GLN B 1 353 ? 133.793 73.471  121.261 1.00 24.45 ? 332  GLN B NE2 1 
ATOM   6322  N N   . GLY B 1 354 ? 133.953 73.630  126.828 1.00 23.56 ? 333  GLY B N   1 
ATOM   6323  C CA  . GLY B 1 354 ? 133.623 72.760  127.939 1.00 23.56 ? 333  GLY B CA  1 
ATOM   6324  C C   . GLY B 1 354 ? 132.122 72.624  128.076 1.00 23.56 ? 333  GLY B C   1 
ATOM   6325  O O   . GLY B 1 354 ? 131.373 72.928  127.148 1.00 23.56 ? 333  GLY B O   1 
ATOM   6326  N N   . ASP B 1 355 ? 131.704 72.161  129.243 1.00 24.39 ? 334  ASP B N   1 
ATOM   6327  C CA  . ASP B 1 355 ? 130.287 72.046  129.539 1.00 24.39 ? 334  ASP B CA  1 
ATOM   6328  C C   . ASP B 1 355 ? 129.658 73.434  129.521 1.00 24.39 ? 334  ASP B C   1 
ATOM   6329  O O   . ASP B 1 355 ? 130.076 74.307  130.297 1.00 24.39 ? 334  ASP B O   1 
ATOM   6330  C CB  . ASP B 1 355 ? 130.083 71.381  130.895 1.00 24.39 ? 334  ASP B CB  1 
ATOM   6331  C CG  . ASP B 1 355 ? 128.635 71.044  131.166 1.00 24.39 ? 334  ASP B CG  1 
ATOM   6332  O OD1 . ASP B 1 355 ? 128.153 70.030  130.623 1.00 24.39 ? 334  ASP B OD1 1 
ATOM   6333  O OD2 . ASP B 1 355 ? 127.979 71.788  131.923 1.00 24.39 ? 334  ASP B OD2 1 
ATOM   6334  N N   . PRO B 1 356 ? 128.659 73.682  128.674 1.00 21.58 ? 335  PRO B N   1 
ATOM   6335  C CA  . PRO B 1 356 ? 128.136 75.039  128.496 1.00 21.58 ? 335  PRO B CA  1 
ATOM   6336  C C   . PRO B 1 356 ? 127.235 75.524  129.618 1.00 21.58 ? 335  PRO B C   1 
ATOM   6337  O O   . PRO B 1 356 ? 126.542 76.526  129.432 1.00 21.58 ? 335  PRO B O   1 
ATOM   6338  C CB  . PRO B 1 356 ? 127.337 74.925  127.185 1.00 21.58 ? 335  PRO B CB  1 
ATOM   6339  C CG  . PRO B 1 356 ? 127.738 73.619  126.575 1.00 21.58 ? 335  PRO B CG  1 
ATOM   6340  C CD  . PRO B 1 356 ? 128.055 72.739  127.725 1.00 21.58 ? 335  PRO B CD  1 
ATOM   6341  N N   . ARG B 1 357 ? 127.217 74.852  130.767 1.00 25.97 ? 336  ARG B N   1 
ATOM   6342  C CA  . ARG B 1 357 ? 126.193 75.093  131.772 1.00 25.97 ? 336  ARG B CA  1 
ATOM   6343  C C   . ARG B 1 357 ? 126.741 75.648  133.078 1.00 25.97 ? 336  ARG B C   1 
ATOM   6344  O O   . ARG B 1 357 ? 126.087 75.492  134.114 1.00 25.97 ? 336  ARG B O   1 
ATOM   6345  C CB  . ARG B 1 357 ? 125.420 73.808  132.069 1.00 25.97 ? 336  ARG B CB  1 
ATOM   6346  C CG  . ARG B 1 357 ? 124.707 73.188  130.891 1.00 25.97 ? 336  ARG B CG  1 
ATOM   6347  C CD  . ARG B 1 357 ? 124.285 71.773  131.232 1.00 25.97 ? 336  ARG B CD  1 
ATOM   6348  N NE  . ARG B 1 357 ? 125.436 70.905  131.454 1.00 25.97 ? 336  ARG B NE  1 
ATOM   6349  C CZ  . ARG B 1 357 ? 125.366 69.694  131.997 1.00 25.97 ? 336  ARG B CZ  1 
ATOM   6350  N NH1 . ARG B 1 357 ? 124.196 69.205  132.380 1.00 25.97 ? 336  ARG B NH1 1 
ATOM   6351  N NH2 . ARG B 1 357 ? 126.465 68.973  132.159 1.00 25.97 ? 336  ARG B NH2 1 
ATOM   6352  N N   . GLU B 1 358 ? 127.918 76.275  133.097 1.00 29.68 ? 337  GLU B N   1 
ATOM   6353  C CA  . GLU B 1 358 ? 128.251 76.833  134.401 1.00 29.68 ? 337  GLU B CA  1 
ATOM   6354  C C   . GLU B 1 358 ? 128.341 78.354  134.431 1.00 29.68 ? 337  GLU B C   1 
ATOM   6355  O O   . GLU B 1 358 ? 127.409 79.007  134.913 1.00 29.68 ? 337  GLU B O   1 
ATOM   6356  C CB  . GLU B 1 358 ? 129.570 76.231  134.889 1.00 29.68 ? 337  GLU B CB  1 
ATOM   6357  C CG  . GLU B 1 358 ? 129.463 74.766  135.266 1.00 29.68 ? 337  GLU B CG  1 
ATOM   6358  C CD  . GLU B 1 358 ? 130.760 74.201  135.810 1.00 29.68 ? 337  GLU B CD  1 
ATOM   6359  O OE1 . GLU B 1 358 ? 131.802 74.884  135.705 1.00 29.68 ? 337  GLU B OE1 1 
ATOM   6360  O OE2 . GLU B 1 358 ? 130.734 73.073  136.344 1.00 29.68 ? 337  GLU B OE2 1 
ATOM   6361  N N   . SER B 1 359 ? 129.420 78.940  133.911 1.00 28.86 ? 338  SER B N   1 
ATOM   6362  C CA  . SER B 1 359 ? 129.441 80.386  133.721 1.00 28.86 ? 338  SER B CA  1 
ATOM   6363  C C   . SER B 1 359 ? 130.442 80.847  132.669 1.00 28.86 ? 338  SER B C   1 
ATOM   6364  O O   . SER B 1 359 ? 130.519 82.042  132.370 1.00 28.86 ? 338  SER B O   1 
ATOM   6365  C CB  . SER B 1 359 ? 129.737 81.079  135.052 1.00 28.86 ? 338  SER B CB  1 
ATOM   6366  O OG  . SER B 1 359 ? 131.046 80.780  135.505 1.00 28.86 ? 338  SER B OG  1 
ATOM   6367  N N   . ASP B 1 360 ? 131.209 79.920  132.097 1.00 27.77 ? 339  ASP B N   1 
ATOM   6368  C CA  . ASP B 1 360 ? 132.497 80.316  131.538 1.00 27.77 ? 339  ASP B CA  1 
ATOM   6369  C C   . ASP B 1 360 ? 132.835 79.736  130.179 1.00 27.77 ? 339  ASP B C   1 
ATOM   6370  O O   . ASP B 1 360 ? 133.807 80.197  129.573 1.00 27.77 ? 339  ASP B O   1 
ATOM   6371  C CB  . ASP B 1 360 ? 133.622 79.948  132.515 1.00 27.77 ? 339  ASP B CB  1 
ATOM   6372  C CG  . ASP B 1 360 ? 133.554 78.499  132.964 1.00 27.77 ? 339  ASP B CG  1 
ATOM   6373  O OD1 . ASP B 1 360 ? 132.696 77.754  132.448 1.00 27.77 ? 339  ASP B OD1 1 
ATOM   6374  O OD2 . ASP B 1 360 ? 134.353 78.106  133.838 1.00 27.77 ? 339  ASP B OD2 1 
ATOM   6375  N N   . THR B 1 361 ? 132.109 78.744  129.682 1.00 24.00 ? 340  THR B N   1 
ATOM   6376  C CA  . THR B 1 361 ? 132.397 78.237  128.352 1.00 24.00 ? 340  THR B CA  1 
ATOM   6377  C C   . THR B 1 361 ? 132.081 79.306  127.316 1.00 24.00 ? 340  THR B C   1 
ATOM   6378  O O   . THR B 1 361 ? 131.074 80.011  127.416 1.00 24.00 ? 340  THR B O   1 
ATOM   6379  C CB  . THR B 1 361 ? 131.591 76.973  128.078 1.00 24.00 ? 340  THR B CB  1 
ATOM   6380  O OG1 . THR B 1 361 ? 131.788 76.044  129.149 1.00 24.00 ? 340  THR B OG1 1 
ATOM   6381  C CG2 . THR B 1 361 ? 132.051 76.334  126.798 1.00 24.00 ? 340  THR B CG2 1 
ATOM   6382  N N   . MET B 1 362 ? 132.959 79.440  126.326 1.00 24.32 ? 341  MET B N   1 
ATOM   6383  C CA  . MET B 1 362 ? 132.779 80.413  125.259 1.00 24.32 ? 341  MET B CA  1 
ATOM   6384  C C   . MET B 1 362 ? 132.228 79.799  123.983 1.00 24.32 ? 341  MET B C   1 
ATOM   6385  O O   . MET B 1 362 ? 131.348 80.386  123.347 1.00 24.32 ? 341  MET B O   1 
ATOM   6386  C CB  . MET B 1 362 ? 134.106 81.113  124.957 1.00 24.32 ? 341  MET B CB  1 
ATOM   6387  C CG  . MET B 1 362 ? 134.343 82.369  125.767 1.00 24.32 ? 341  MET B CG  1 
ATOM   6388  S SD  . MET B 1 362 ? 136.075 82.811  125.977 1.00 24.32 ? 341  MET B SD  1 
ATOM   6389  C CE  . MET B 1 362 ? 136.427 82.034  127.545 1.00 24.32 ? 341  MET B CE  1 
ATOM   6390  N N   . ILE B 1 363 ? 132.725 78.630  123.596 1.00 20.09 ? 342  ILE B N   1 
ATOM   6391  C CA  . ILE B 1 363 ? 132.260 77.907  122.421 1.00 20.09 ? 342  ILE B CA  1 
ATOM   6392  C C   . ILE B 1 363 ? 131.533 76.657  122.893 1.00 20.09 ? 342  ILE B C   1 
ATOM   6393  O O   . ILE B 1 363 ? 132.059 75.894  123.712 1.00 20.09 ? 342  ILE B O   1 
ATOM   6394  C CB  . ILE B 1 363 ? 133.429 77.578  121.473 1.00 20.09 ? 342  ILE B CB  1 
ATOM   6395  C CG1 . ILE B 1 363 ? 132.935 76.882  120.207 1.00 20.09 ? 342  ILE B CG1 1 
ATOM   6396  C CG2 . ILE B 1 363 ? 134.516 76.800  122.181 1.00 20.09 ? 342  ILE B CG2 1 
ATOM   6397  C CD1 . ILE B 1 363 ? 132.094 77.746  119.347 1.00 20.09 ? 342  ILE B CD1 1 
ATOM   6398  N N   . GLY B 1 364 ? 130.314 76.461  122.398 1.00 18.28 ? 343  GLY B N   1 
ATOM   6399  C CA  . GLY B 1 364 ? 129.450 75.425  122.929 1.00 18.28 ? 343  GLY B CA  1 
ATOM   6400  C C   . GLY B 1 364 ? 129.331 74.186  122.071 1.00 18.28 ? 343  GLY B C   1 
ATOM   6401  O O   . GLY B 1 364 ? 130.312 73.736  121.473 1.00 18.28 ? 343  GLY B O   1 
ATOM   6402  N N   . ALA B 1 365 ? 128.126 73.627  122.001 1.00 17.13 ? 344  ALA B N   1 
ATOM   6403  C CA  . ALA B 1 365 ? 127.881 72.372  121.311 1.00 17.13 ? 344  ALA B CA  1 
ATOM   6404  C C   . ALA B 1 365 ? 126.981 72.591  120.104 1.00 17.13 ? 344  ALA B C   1 
ATOM   6405  O O   . ALA B 1 365 ? 126.185 73.533  120.061 1.00 17.13 ? 344  ALA B O   1 
ATOM   6406  C CB  . ALA B 1 365 ? 127.240 71.342  122.245 1.00 17.13 ? 344  ALA B CB  1 
ATOM   6407  N N   . GLN B 1 366 ? 127.116 71.707  119.120 1.00 19.65 ? 345  GLN B N   1 
ATOM   6408  C CA  . GLN B 1 366 ? 126.240 71.751  117.964 1.00 19.65 ? 345  GLN B CA  1 
ATOM   6409  C C   . GLN B 1 366 ? 124.838 71.289  118.356 1.00 19.65 ? 345  GLN B C   1 
ATOM   6410  O O   . GLN B 1 366 ? 124.641 70.625  119.372 1.00 19.65 ? 345  GLN B O   1 
ATOM   6411  C CB  . GLN B 1 366 ? 126.778 70.873  116.838 1.00 19.65 ? 345  GLN B CB  1 
ATOM   6412  C CG  . GLN B 1 366 ? 128.131 71.290  116.317 1.00 19.65 ? 345  GLN B CG  1 
ATOM   6413  C CD  . GLN B 1 366 ? 128.130 72.704  115.802 1.00 19.65 ? 345  GLN B CD  1 
ATOM   6414  O OE1 . GLN B 1 366 ? 128.769 73.578  116.376 1.00 19.65 ? 345  GLN B OE1 1 
ATOM   6415  N NE2 . GLN B 1 366 ? 127.347 72.957  114.768 1.00 19.65 ? 345  GLN B NE2 1 
ATOM   6416  N N   . ALA B 1 367 ? 123.853 71.648  117.531 1.00 17.37 ? 346  ALA B N   1 
ATOM   6417  C CA  . ALA B 1 367 ? 122.465 71.344  117.870 1.00 17.37 ? 346  ALA B CA  1 
ATOM   6418  C C   . ALA B 1 367 ? 122.164 69.856  117.732 1.00 17.37 ? 346  ALA B C   1 
ATOM   6419  O O   . ALA B 1 367 ? 121.529 69.260  118.607 1.00 17.37 ? 346  ALA B O   1 
ATOM   6420  C CB  . ALA B 1 367 ? 121.520 72.162  116.994 1.00 17.37 ? 346  ALA B CB  1 
ATOM   6421  N N   . SER B 1 368 ? 122.601 69.240  116.639 1.00 20.63 ? 347  SER B N   1 
ATOM   6422  C CA  . SER B 1 368 ? 122.252 67.858  116.340 1.00 20.63 ? 347  SER B CA  1 
ATOM   6423  C C   . SER B 1 368 ? 123.497 67.085  115.927 1.00 20.63 ? 347  SER B C   1 
ATOM   6424  O O   . SER B 1 368 ? 124.587 67.644  115.783 1.00 20.63 ? 347  SER B O   1 
ATOM   6425  C CB  . SER B 1 368 ? 121.184 67.785  115.242 1.00 20.63 ? 347  SER B CB  1 
ATOM   6426  O OG  . SER B 1 368 ? 121.011 66.453  114.792 1.00 20.63 ? 347  SER B OG  1 
ATOM   6427  N N   . SER B 1 369 ? 123.323 65.775  115.744 1.00 22.68 ? 348  SER B N   1 
ATOM   6428  C CA  . SER B 1 369 ? 124.410 64.943  115.242 1.00 22.68 ? 348  SER B CA  1 
ATOM   6429  C C   . SER B 1 369 ? 124.657 65.197  113.761 1.00 22.68 ? 348  SER B C   1 
ATOM   6430  O O   . SER B 1 369 ? 125.811 65.237  113.314 1.00 22.68 ? 348  SER B O   1 
ATOM   6431  C CB  . SER B 1 369 ? 124.098 63.468  115.488 1.00 22.68 ? 348  SER B CB  1 
ATOM   6432  O OG  . SER B 1 369 ? 123.075 63.015  114.619 1.00 22.68 ? 348  SER B OG  1 
ATOM   6433  N N   . GLU B 1 370 ? 123.584 65.368  112.983 1.00 25.07 ? 349  GLU B N   1 
ATOM   6434  C CA  . GLU B 1 370 ? 123.733 65.696  111.571 1.00 25.07 ? 349  GLU B CA  1 
ATOM   6435  C C   . GLU B 1 370 ? 124.475 67.005  111.372 1.00 25.07 ? 349  GLU B C   1 
ATOM   6436  O O   . GLU B 1 370 ? 125.114 67.192  110.330 1.00 25.07 ? 349  GLU B O   1 
ATOM   6437  C CB  . GLU B 1 370 ? 122.366 65.769  110.892 1.00 25.07 ? 349  GLU B CB  1 
ATOM   6438  C CG  . GLU B 1 370 ? 121.990 64.518  110.120 1.00 25.07 ? 349  GLU B CG  1 
ATOM   6439  C CD  . GLU B 1 370 ? 120.589 64.589  109.545 1.00 25.07 ? 349  GLU B CD  1 
ATOM   6440  O OE1 . GLU B 1 370 ? 119.951 63.526  109.398 1.00 25.07 ? 349  GLU B OE1 1 
ATOM   6441  O OE2 . GLU B 1 370 ? 120.127 65.708  109.239 1.00 25.07 ? 349  GLU B OE2 1 
ATOM   6442  N N   . GLN B 1 371 ? 124.423 67.907  112.354 1.00 22.38 ? 350  GLN B N   1 
ATOM   6443  C CA  . GLN B 1 371 ? 125.201 69.135  112.260 1.00 22.38 ? 350  GLN B CA  1 
ATOM   6444  C C   . GLN B 1 371 ? 126.695 68.834  112.280 1.00 22.38 ? 350  GLN B C   1 
ATOM   6445  O O   . GLN B 1 371 ? 127.443 69.315  111.418 1.00 22.38 ? 350  GLN B O   1 
ATOM   6446  C CB  . GLN B 1 371 ? 124.813 70.089  113.385 1.00 22.38 ? 350  GLN B CB  1 
ATOM   6447  C CG  . GLN B 1 371 ? 125.069 71.548  113.059 1.00 22.38 ? 350  GLN B CG  1 
ATOM   6448  C CD  . GLN B 1 371 ? 124.546 71.951  111.693 1.00 22.38 ? 350  GLN B CD  1 
ATOM   6449  O OE1 . GLN B 1 371 ? 125.242 72.611  110.922 1.00 22.38 ? 350  GLN B OE1 1 
ATOM   6450  N NE2 . GLN B 1 371 ? 123.310 71.570  111.392 1.00 22.38 ? 350  GLN B NE2 1 
ATOM   6451  N N   . LYS B 1 372 ? 127.148 68.028  113.247 1.00 23.40 ? 351  LYS B N   1 
ATOM   6452  C CA  . LYS B 1 372 ? 128.521 67.534  113.201 1.00 23.40 ? 351  LYS B CA  1 
ATOM   6453  C C   . LYS B 1 372 ? 128.826 66.840  111.889 1.00 23.40 ? 351  LYS B C   1 
ATOM   6454  O O   . LYS B 1 372 ? 129.912 67.006  111.336 1.00 23.40 ? 351  LYS B O   1 
ATOM   6455  C CB  . LYS B 1 372 ? 128.829 66.567  114.342 1.00 23.40 ? 351  LYS B CB  1 
ATOM   6456  C CG  . LYS B 1 372 ? 128.419 66.931  115.726 1.00 23.40 ? 351  LYS B CG  1 
ATOM   6457  C CD  . LYS B 1 372 ? 129.129 65.939  116.627 1.00 23.40 ? 351  LYS B CD  1 
ATOM   6458  C CE  . LYS B 1 372 ? 130.366 66.536  117.260 1.00 23.40 ? 351  LYS B CE  1 
ATOM   6459  N NZ  . LYS B 1 372 ? 130.831 65.740  118.433 1.00 23.40 ? 351  LYS B NZ  1 
ATOM   6460  N N   . GLU B 1 373 ? 127.910 66.003  111.403 1.00 25.62 ? 352  GLU B N   1 
ATOM   6461  C CA  . GLU B 1 373 ? 128.213 65.248  110.191 1.00 25.62 ? 352  GLU B CA  1 
ATOM   6462  C C   . GLU B 1 373 ? 128.483 66.186  109.021 1.00 25.62 ? 352  GLU B C   1 
ATOM   6463  O O   . GLU B 1 373 ? 129.490 66.049  108.314 1.00 25.62 ? 352  GLU B O   1 
ATOM   6464  C CB  . GLU B 1 373 ? 127.072 64.285  109.869 1.00 25.62 ? 352  GLU B CB  1 
ATOM   6465  C CG  . GLU B 1 373 ? 126.709 63.344  111.008 1.00 25.62 ? 352  GLU B CG  1 
ATOM   6466  C CD  . GLU B 1 373 ? 127.917 62.857  111.789 1.00 25.62 ? 352  GLU B CD  1 
ATOM   6467  O OE1 . GLU B 1 373 ? 127.894 62.947  113.033 1.00 25.62 ? 352  GLU B OE1 1 
ATOM   6468  O OE2 . GLU B 1 373 ? 128.882 62.368  111.164 1.00 25.62 ? 352  GLU B OE2 1 
ATOM   6469  N N   . LYS B 1 374 ? 127.608 67.174  108.831 1.00 24.67 ? 353  LYS B N   1 
ATOM   6470  C CA  . LYS B 1 374 ? 127.793 68.134  107.750 1.00 24.67 ? 353  LYS B CA  1 
ATOM   6471  C C   . LYS B 1 374 ? 129.069 68.946  107.940 1.00 24.67 ? 353  LYS B C   1 
ATOM   6472  O O   . LYS B 1 374 ? 129.831 69.149  106.987 1.00 24.67 ? 353  LYS B O   1 
ATOM   6473  C CB  . LYS B 1 374 ? 126.576 69.054  107.660 1.00 24.67 ? 353  LYS B CB  1 
ATOM   6474  C CG  . LYS B 1 374 ? 126.521 69.888  106.395 1.00 24.67 ? 353  LYS B CG  1 
ATOM   6475  C CD  . LYS B 1 374 ? 125.185 70.591  106.256 1.00 24.67 ? 353  LYS B CD  1 
ATOM   6476  C CE  . LYS B 1 374 ? 125.339 71.926  105.553 1.00 24.67 ? 353  LYS B CE  1 
ATOM   6477  N NZ  . LYS B 1 374 ? 126.433 72.733  106.158 1.00 24.67 ? 353  LYS B NZ  1 
ATOM   6478  N N   . ILE B 1 375 ? 129.325 69.412  109.166 1.00 23.12 ? 354  ILE B N   1 
ATOM   6479  C CA  . ILE B 1 375 ? 130.491 70.258  109.403 1.00 23.12 ? 354  ILE B CA  1 
ATOM   6480  C C   . ILE B 1 375 ? 131.777 69.471  109.211 1.00 23.12 ? 354  ILE B C   1 
ATOM   6481  O O   . ILE B 1 375 ? 132.761 69.990  108.677 1.00 23.12 ? 354  ILE B O   1 
ATOM   6482  C CB  . ILE B 1 375 ? 130.422 70.890  110.801 1.00 23.12 ? 354  ILE B CB  1 
ATOM   6483  C CG1 . ILE B 1 375 ? 129.234 71.828  110.885 1.00 23.12 ? 354  ILE B CG1 1 
ATOM   6484  C CG2 . ILE B 1 375 ? 131.685 71.662  111.098 1.00 23.12 ? 354  ILE B CG2 1 
ATOM   6485  C CD1 . ILE B 1 375 ? 128.953 72.250  112.269 1.00 23.12 ? 354  ILE B CD1 1 
ATOM   6486  N N   . LEU B 1 376 ? 131.797 68.213  109.649 1.00 22.98 ? 355  LEU B N   1 
ATOM   6487  C CA  . LEU B 1 376 ? 132.984 67.385  109.491 1.00 22.98 ? 355  LEU B CA  1 
ATOM   6488  C C   . LEU B 1 376 ? 133.218 67.035  108.029 1.00 22.98 ? 355  LEU B C   1 
ATOM   6489  O O   . LEU B 1 376 ? 134.367 66.987  107.574 1.00 22.98 ? 355  LEU B O   1 
ATOM   6490  C CB  . LEU B 1 376 ? 132.851 66.123  110.339 1.00 22.98 ? 355  LEU B CB  1 
ATOM   6491  C CG  . LEU B 1 376 ? 132.982 66.312  111.851 1.00 22.98 ? 355  LEU B CG  1 
ATOM   6492  C CD1 . LEU B 1 376 ? 132.602 65.038  112.579 1.00 22.98 ? 355  LEU B CD1 1 
ATOM   6493  C CD2 . LEU B 1 376 ? 134.388 66.735  112.215 1.00 22.98 ? 355  LEU B CD2 1 
ATOM   6494  N N   . SER B 1 377 ? 132.144 66.801  107.270 1.00 26.19 ? 356  SER B N   1 
ATOM   6495  C CA  . SER B 1 377 ? 132.301 66.619  105.831 1.00 26.19 ? 356  SER B CA  1 
ATOM   6496  C C   . SER B 1 377 ? 132.887 67.867  105.186 1.00 26.19 ? 356  SER B C   1 
ATOM   6497  O O   . SER B 1 377 ? 133.782 67.779  104.336 1.00 26.19 ? 356  SER B O   1 
ATOM   6498  C CB  . SER B 1 377 ? 130.959 66.269  105.193 1.00 26.19 ? 356  SER B CB  1 
ATOM   6499  O OG  . SER B 1 377 ? 131.014 66.418  103.787 1.00 26.19 ? 356  SER B OG  1 
ATOM   6500  N N   . TYR B 1 378 ? 132.399 69.043  105.588 1.00 27.92 ? 357  TYR B N   1 
ATOM   6501  C CA  . TYR B 1 378 ? 132.931 70.289  105.046 1.00 27.92 ? 357  TYR B CA  1 
ATOM   6502  C C   . TYR B 1 378 ? 134.392 70.484  105.433 1.00 27.92 ? 357  TYR B C   1 
ATOM   6503  O O   . TYR B 1 378 ? 135.199 70.948  104.622 1.00 27.92 ? 357  TYR B O   1 
ATOM   6504  C CB  . TYR B 1 378 ? 132.083 71.464  105.521 1.00 27.92 ? 357  TYR B CB  1 
ATOM   6505  C CG  . TYR B 1 378 ? 130.994 71.843  104.549 1.00 27.92 ? 357  TYR B CG  1 
ATOM   6506  C CD1 . TYR B 1 378 ? 131.303 72.298  103.276 1.00 27.92 ? 357  TYR B CD1 1 
ATOM   6507  C CD2 . TYR B 1 378 ? 129.657 71.736  104.900 1.00 27.92 ? 357  TYR B CD2 1 
ATOM   6508  C CE1 . TYR B 1 378 ? 130.311 72.643  102.383 1.00 27.92 ? 357  TYR B CE1 1 
ATOM   6509  C CE2 . TYR B 1 378 ? 128.658 72.078  104.014 1.00 27.92 ? 357  TYR B CE2 1 
ATOM   6510  C CZ  . TYR B 1 378 ? 128.988 72.532  102.759 1.00 27.92 ? 357  TYR B CZ  1 
ATOM   6511  O OH  . TYR B 1 378 ? 127.991 72.872  101.875 1.00 27.92 ? 357  TYR B OH  1 
ATOM   6512  N N   . LEU B 1 379 ? 134.745 70.144  106.672 1.00 25.91 ? 358  LEU B N   1 
ATOM   6513  C CA  . LEU B 1 379 ? 136.133 70.245  107.106 1.00 25.91 ? 358  LEU B CA  1 
ATOM   6514  C C   . LEU B 1 379 ? 137.019 69.305  106.307 1.00 25.91 ? 358  LEU B C   1 
ATOM   6515  O O   . LEU B 1 379 ? 138.158 69.647  105.976 1.00 25.91 ? 358  LEU B O   1 
ATOM   6516  C CB  . LEU B 1 379 ? 136.240 69.945  108.601 1.00 25.91 ? 358  LEU B CB  1 
ATOM   6517  C CG  . LEU B 1 379 ? 136.318 71.165  109.513 1.00 25.91 ? 358  LEU B CG  1 
ATOM   6518  C CD1 . LEU B 1 379 ? 135.177 72.098  109.202 1.00 25.91 ? 358  LEU B CD1 1 
ATOM   6519  C CD2 . LEU B 1 379 ? 136.276 70.750  110.968 1.00 25.91 ? 358  LEU B CD2 1 
ATOM   6520  N N   . ASP B 1 380 ? 136.514 68.112  105.990 1.00 30.83 ? 359  ASP B N   1 
ATOM   6521  C CA  . ASP B 1 380 ? 137.257 67.192  105.136 1.00 30.83 ? 359  ASP B CA  1 
ATOM   6522  C C   . ASP B 1 380 ? 137.475 67.790  103.751 1.00 30.83 ? 359  ASP B C   1 
ATOM   6523  O O   . ASP B 1 380 ? 138.586 67.743  103.203 1.00 30.83 ? 359  ASP B O   1 
ATOM   6524  C CB  . ASP B 1 380 ? 136.507 65.863  105.041 1.00 30.83 ? 359  ASP B CB  1 
ATOM   6525  C CG  . ASP B 1 380 ? 137.350 64.759  104.450 1.00 30.83 ? 359  ASP B CG  1 
ATOM   6526  O OD1 . ASP B 1 380 ? 138.552 64.992  104.220 1.00 30.83 ? 359  ASP B OD1 1 
ATOM   6527  O OD2 . ASP B 1 380 ? 136.813 63.657  104.216 1.00 30.83 ? 359  ASP B OD2 1 
ATOM   6528  N N   . ILE B 1 381 ? 136.417 68.365  103.172 1.00 29.58 ? 360  ILE B N   1 
ATOM   6529  C CA  . ILE B 1 381 ? 136.530 68.982  101.853 1.00 29.58 ? 360  ILE B CA  1 
ATOM   6530  C C   . ILE B 1 381 ? 137.558 70.104  101.880 1.00 29.58 ? 360  ILE B C   1 
ATOM   6531  O O   . ILE B 1 381 ? 138.374 70.242  100.962 1.00 29.58 ? 360  ILE B O   1 
ATOM   6532  C CB  . ILE B 1 381 ? 135.157 69.490  101.373 1.00 29.58 ? 360  ILE B CB  1 
ATOM   6533  C CG1 . ILE B 1 381 ? 134.144 68.347  101.325 1.00 29.58 ? 360  ILE B CG1 1 
ATOM   6534  C CG2 . ILE B 1 381 ? 135.278 70.140  100.002 1.00 29.58 ? 360  ILE B CG2 1 
ATOM   6535  C CD1 . ILE B 1 381 ? 132.712 68.807  101.213 1.00 29.58 ? 360  ILE B CD1 1 
ATOM   6536  N N   . GLY B 1 382 ? 137.534 70.920  102.933 1.00 30.42 ? 361  GLY B N   1 
ATOM   6537  C CA  . GLY B 1 382 ? 138.495 72.004  103.043 1.00 30.42 ? 361  GLY B CA  1 
ATOM   6538  C C   . GLY B 1 382 ? 139.915 71.512  103.229 1.00 30.42 ? 361  GLY B C   1 
ATOM   6539  O O   . GLY B 1 382 ? 140.854 72.066  102.650 1.00 30.42 ? 361  GLY B O   1 
ATOM   6540  N N   . LYS B 1 383 ? 140.094 70.470  104.041 1.00 31.40 ? 362  LYS B N   1 
ATOM   6541  C CA  . LYS B 1 383 ? 141.426 69.921  104.264 1.00 31.40 ? 362  LYS B CA  1 
ATOM   6542  C C   . LYS B 1 383 ? 142.016 69.373  102.974 1.00 31.40 ? 362  LYS B C   1 
ATOM   6543  O O   . LYS B 1 383 ? 143.211 69.544  102.709 1.00 31.40 ? 362  LYS B O   1 
ATOM   6544  C CB  . LYS B 1 383 ? 141.367 68.831  105.334 1.00 31.40 ? 362  LYS B CB  1 
ATOM   6545  C CG  . LYS B 1 383 ? 141.472 69.352  106.751 1.00 31.40 ? 362  LYS B CG  1 
ATOM   6546  C CD  . LYS B 1 383 ? 142.125 68.336  107.668 1.00 31.40 ? 362  LYS B CD  1 
ATOM   6547  C CE  . LYS B 1 383 ? 141.162 67.219  108.025 1.00 31.40 ? 362  LYS B CE  1 
ATOM   6548  N NZ  . LYS B 1 383 ? 141.281 66.817  109.453 1.00 31.40 ? 362  LYS B NZ  1 
ATOM   6549  N N   . LYS B 1 384 ? 141.197 68.714  102.158 1.00 33.08 ? 363  LYS B N   1 
ATOM   6550  C CA  . LYS B 1 384 ? 141.709 68.083  100.947 1.00 33.08 ? 363  LYS B CA  1 
ATOM   6551  C C   . LYS B 1 384 ? 141.652 68.988  99.722  1.00 33.08 ? 363  LYS B C   1 
ATOM   6552  O O   . LYS B 1 384 ? 142.191 68.618  98.675  1.00 33.08 ? 363  LYS B O   1 
ATOM   6553  C CB  . LYS B 1 384 ? 140.955 66.777  100.669 1.00 33.08 ? 363  LYS B CB  1 
ATOM   6554  C CG  . LYS B 1 384 ? 140.699 65.931  101.912 1.00 33.08 ? 363  LYS B CG  1 
ATOM   6555  C CD  . LYS B 1 384 ? 141.968 65.733  102.728 1.00 33.08 ? 363  LYS B CD  1 
ATOM   6556  C CE  . LYS B 1 384 ? 141.670 65.116  104.081 1.00 33.08 ? 363  LYS B CE  1 
ATOM   6557  N NZ  . LYS B 1 384 ? 142.801 65.293  105.029 1.00 33.08 ? 363  LYS B NZ  1 
ATOM   6558  N N   . GLU B 1 385 ? 141.020 70.160  99.820  1.00 34.95 ? 364  GLU B N   1 
ATOM   6559  C CA  . GLU B 1 385 ? 141.009 71.089  98.694  1.00 34.95 ? 364  GLU B CA  1 
ATOM   6560  C C   . GLU B 1 385 ? 142.332 71.832  98.559  1.00 34.95 ? 364  GLU B C   1 
ATOM   6561  O O   . GLU B 1 385 ? 142.783 72.103  97.440  1.00 34.95 ? 364  GLU B O   1 
ATOM   6562  C CB  . GLU B 1 385 ? 139.862 72.087  98.839  1.00 34.95 ? 364  GLU B CB  1 
ATOM   6563  C CG  . GLU B 1 385 ? 139.477 72.766  97.535  1.00 34.95 ? 364  GLU B CG  1 
ATOM   6564  C CD  . GLU B 1 385 ? 138.170 73.529  97.636  1.00 34.95 ? 364  GLU B CD  1 
ATOM   6565  O OE1 . GLU B 1 385 ? 137.702 73.765  98.772  1.00 34.95 ? 364  GLU B OE1 1 
ATOM   6566  O OE2 . GLU B 1 385 ? 137.612 73.893  96.580  1.00 34.95 ? 364  GLU B OE2 1 
ATOM   6567  N N   . GLY B 1 386 ? 142.965 72.167  99.679  1.00 33.12 ? 365  GLY B N   1 
ATOM   6568  C CA  . GLY B 1 386 ? 144.190 72.939  99.648  1.00 33.12 ? 365  GLY B CA  1 
ATOM   6569  C C   . GLY B 1 386 ? 144.130 74.152  100.549 1.00 33.12 ? 365  GLY B C   1 
ATOM   6570  O O   . GLY B 1 386 ? 144.925 75.085  100.409 1.00 33.12 ? 365  GLY B O   1 
ATOM   6571  N N   . ALA B 1 387 ? 143.179 74.147  101.479 1.00 30.42 ? 366  ALA B N   1 
ATOM   6572  C CA  . ALA B 1 387 ? 143.042 75.207  102.473 1.00 30.42 ? 366  ALA B CA  1 
ATOM   6573  C C   . ALA B 1 387 ? 143.888 74.831  103.679 1.00 30.42 ? 366  ALA B C   1 
ATOM   6574  O O   . ALA B 1 387 ? 143.478 74.013  104.505 1.00 30.42 ? 366  ALA B O   1 
ATOM   6575  C CB  . ALA B 1 387 ? 141.583 75.396  102.864 1.00 30.42 ? 366  ALA B CB  1 
ATOM   6576  N N   . GLU B 1 388 ? 145.076 75.424  103.781 1.00 30.24 ? 367  GLU B N   1 
ATOM   6577  C CA  . GLU B 1 388 ? 145.943 75.147  104.917 1.00 30.24 ? 367  GLU B CA  1 
ATOM   6578  C C   . GLU B 1 388 ? 145.245 75.528  106.213 1.00 30.24 ? 367  GLU B C   1 
ATOM   6579  O O   . GLU B 1 388 ? 144.555 76.548  106.292 1.00 30.24 ? 367  GLU B O   1 
ATOM   6580  C CB  . GLU B 1 388 ? 147.261 75.905  104.779 1.00 30.24 ? 367  GLU B CB  1 
ATOM   6581  C CG  . GLU B 1 388 ? 147.104 77.344  104.343 1.00 30.24 ? 367  GLU B CG  1 
ATOM   6582  C CD  . GLU B 1 388 ? 148.422 78.087  104.324 1.00 30.24 ? 367  GLU B CD  1 
ATOM   6583  O OE1 . GLU B 1 388 ? 149.420 77.539  104.835 1.00 30.24 ? 367  GLU B OE1 1 
ATOM   6584  O OE2 . GLU B 1 388 ? 148.461 79.216  103.792 1.00 30.24 ? 367  GLU B OE2 1 
ATOM   6585  N N   . VAL B 1 389 ? 145.424 74.697  107.233 1.00 25.93 ? 368  VAL B N   1 
ATOM   6586  C CA  . VAL B 1 389 ? 144.671 74.819  108.475 1.00 25.93 ? 368  VAL B CA  1 
ATOM   6587  C C   . VAL B 1 389 ? 145.474 75.670  109.450 1.00 25.93 ? 368  VAL B C   1 
ATOM   6588  O O   . VAL B 1 389 ? 146.483 75.221  109.997 1.00 25.93 ? 368  VAL B O   1 
ATOM   6589  C CB  . VAL B 1 389 ? 144.356 73.445  109.072 1.00 25.93 ? 368  VAL B CB  1 
ATOM   6590  C CG1 . VAL B 1 389 ? 143.458 73.601  110.275 1.00 25.93 ? 368  VAL B CG1 1 
ATOM   6591  C CG2 . VAL B 1 389 ? 143.715 72.554  108.025 1.00 25.93 ? 368  VAL B CG2 1 
ATOM   6592  N N   . LEU B 1 390 ? 145.021 76.905  109.672 1.00 24.25 ? 369  LEU B N   1 
ATOM   6593  C CA  . LEU B 1 390 ? 145.683 77.760  110.649 1.00 24.25 ? 369  LEU B CA  1 
ATOM   6594  C C   . LEU B 1 390 ? 145.430 77.272  112.069 1.00 24.25 ? 369  LEU B C   1 
ATOM   6595  O O   . LEU B 1 390 ? 146.326 77.333  112.918 1.00 24.25 ? 369  LEU B O   1 
ATOM   6596  C CB  . LEU B 1 390 ? 145.223 79.206  110.483 1.00 24.25 ? 369  LEU B CB  1 
ATOM   6597  C CG  . LEU B 1 390 ? 145.515 79.834  109.122 1.00 24.25 ? 369  LEU B CG  1 
ATOM   6598  C CD1 . LEU B 1 390 ? 144.964 81.247  109.051 1.00 24.25 ? 369  LEU B CD1 1 
ATOM   6599  C CD2 . LEU B 1 390 ? 147.006 79.818  108.834 1.00 24.25 ? 369  LEU B CD2 1 
ATOM   6600  N N   . THR B 1 391 ? 144.222 76.789  112.350 1.00 21.90 ? 370  THR B N   1 
ATOM   6601  C CA  . THR B 1 391 ? 143.968 76.196  113.660 1.00 21.90 ? 370  THR B CA  1 
ATOM   6602  C C   . THR B 1 391 ? 142.751 75.289  113.579 1.00 21.90 ? 370  THR B C   1 
ATOM   6603  O O   . THR B 1 391 ? 141.909 75.430  112.690 1.00 21.90 ? 370  THR B O   1 
ATOM   6604  C CB  . THR B 1 391 ? 143.762 77.260  114.746 1.00 21.90 ? 370  THR B CB  1 
ATOM   6605  O OG1 . THR B 1 391 ? 143.792 76.638  116.035 1.00 21.90 ? 370  THR B OG1 1 
ATOM   6606  C CG2 . THR B 1 391 ? 142.427 77.932  114.581 1.00 21.90 ? 370  THR B CG2 1 
ATOM   6607  N N   . GLY B 1 392 ? 142.665 74.365  114.539 1.00 20.82 ? 371  GLY B N   1 
ATOM   6608  C CA  . GLY B 1 392 ? 141.536 73.455  114.625 1.00 20.82 ? 371  GLY B CA  1 
ATOM   6609  C C   . GLY B 1 392 ? 141.503 72.465  113.473 1.00 20.82 ? 371  GLY B C   1 
ATOM   6610  O O   . GLY B 1 392 ? 142.523 72.143  112.860 1.00 20.82 ? 371  GLY B O   1 
ATOM   6611  N N   . GLY B 1 393 ? 140.306 71.960  113.186 1.00 23.50 ? 372  GLY B N   1 
ATOM   6612  C CA  . GLY B 1 393 ? 140.121 71.112  112.026 1.00 23.50 ? 372  GLY B CA  1 
ATOM   6613  C C   . GLY B 1 393 ? 139.616 69.716  112.321 1.00 23.50 ? 372  GLY B C   1 
ATOM   6614  O O   . GLY B 1 393 ? 139.758 68.819  111.486 1.00 23.50 ? 372  GLY B O   1 
ATOM   6615  N N   . LYS B 1 394 ? 139.020 69.514  113.491 1.00 27.40 ? 373  LYS B N   1 
ATOM   6616  C CA  . LYS B 1 394 ? 138.558 68.190  113.888 1.00 27.40 ? 373  LYS B CA  1 
ATOM   6617  C C   . LYS B 1 394 ? 137.551 68.343  115.020 1.00 27.40 ? 373  LYS B C   1 
ATOM   6618  O O   . LYS B 1 394 ? 137.219 69.454  115.439 1.00 27.40 ? 373  LYS B O   1 
ATOM   6619  C CB  . LYS B 1 394 ? 139.731 67.295  114.298 1.00 27.40 ? 373  LYS B CB  1 
ATOM   6620  C CG  . LYS B 1 394 ? 140.413 67.716  115.590 1.00 27.40 ? 373  LYS B CG  1 
ATOM   6621  C CD  . LYS B 1 394 ? 141.890 67.366  115.570 1.00 27.40 ? 373  LYS B CD  1 
ATOM   6622  C CE  . LYS B 1 394 ? 142.582 67.801  116.852 1.00 27.40 ? 373  LYS B CE  1 
ATOM   6623  N NZ  . LYS B 1 394 ? 142.975 69.235  116.827 1.00 27.40 ? 373  LYS B NZ  1 
ATOM   6624  N N   . ALA B 1 395 ? 137.071 67.206  115.517 1.00 25.77 ? 374  ALA B N   1 
ATOM   6625  C CA  . ALA B 1 395 ? 136.094 67.195  116.593 1.00 25.77 ? 374  ALA B CA  1 
ATOM   6626  C C   . ALA B 1 395 ? 136.734 67.671  117.898 1.00 25.77 ? 374  ALA B C   1 
ATOM   6627  O O   . ALA B 1 395 ? 137.938 67.924  117.983 1.00 25.77 ? 374  ALA B O   1 
ATOM   6628  C CB  . ALA B 1 395 ? 135.493 65.801  116.745 1.00 25.77 ? 374  ALA B CB  1 
ATOM   6629  N N   . ALA B 1 396 ? 135.909 67.785  118.935 1.00 26.79 ? 375  ALA B N   1 
ATOM   6630  C CA  . ALA B 1 396 ? 136.298 68.383  120.207 1.00 26.79 ? 375  ALA B CA  1 
ATOM   6631  C C   . ALA B 1 396 ? 135.853 67.513  121.374 1.00 26.79 ? 375  ALA B C   1 
ATOM   6632  O O   . ALA B 1 396 ? 135.204 67.979  122.311 1.00 26.79 ? 375  ALA B O   1 
ATOM   6633  C CB  . ALA B 1 396 ? 135.726 69.789  120.341 1.00 26.79 ? 375  ALA B CB  1 
ATOM   6634  N N   . ASP B 1 397 ? 136.178 66.221  121.309 1.00 27.66 ? 376  ASP B N   1 
ATOM   6635  C CA  . ASP B 1 397 ? 135.886 65.291  122.397 1.00 27.66 ? 376  ASP B CA  1 
ATOM   6636  C C   . ASP B 1 397 ? 136.347 65.857  123.732 1.00 27.66 ? 376  ASP B C   1 
ATOM   6637  O O   . ASP B 1 397 ? 137.538 66.106  123.936 1.00 27.66 ? 376  ASP B O   1 
ATOM   6638  C CB  . ASP B 1 397 ? 136.566 63.947  122.125 1.00 27.66 ? 376  ASP B CB  1 
ATOM   6639  C CG  . ASP B 1 397 ? 136.250 62.903  123.184 1.00 27.66 ? 376  ASP B CG  1 
ATOM   6640  O OD1 . ASP B 1 397 ? 136.847 62.959  124.280 1.00 27.66 ? 376  ASP B OD1 1 
ATOM   6641  O OD2 . ASP B 1 397 ? 135.408 62.021  122.915 1.00 27.66 ? 376  ASP B OD2 1 
ATOM   6642  N N   . LEU B 1 398 ? 135.392 66.063  124.639 1.00 27.04 ? 377  LEU B N   1 
ATOM   6643  C CA  . LEU B 1 398 ? 135.645 66.722  125.912 1.00 27.04 ? 377  LEU B CA  1 
ATOM   6644  C C   . LEU B 1 398 ? 135.624 65.773  127.103 1.00 27.04 ? 377  LEU B C   1 
ATOM   6645  O O   . LEU B 1 398 ? 135.777 66.231  128.239 1.00 27.04 ? 377  LEU B O   1 
ATOM   6646  C CB  . LEU B 1 398 ? 134.620 67.840  126.128 1.00 27.04 ? 377  LEU B CB  1 
ATOM   6647  C CG  . LEU B 1 398 ? 134.866 69.122  125.336 1.00 27.04 ? 377  LEU B CG  1 
ATOM   6648  C CD1 . LEU B 1 398 ? 133.754 70.117  125.578 1.00 27.04 ? 377  LEU B CD1 1 
ATOM   6649  C CD2 . LEU B 1 398 ? 136.210 69.724  125.699 1.00 27.04 ? 377  LEU B CD2 1 
ATOM   6650  N N   . GLY B 1 399 ? 135.432 64.475  126.881 1.00 25.75 ? 378  GLY B N   1 
ATOM   6651  C CA  . GLY B 1 399 ? 135.503 63.497  127.950 1.00 25.75 ? 378  GLY B CA  1 
ATOM   6652  C C   . GLY B 1 399 ? 134.433 63.632  129.014 1.00 25.75 ? 378  GLY B C   1 
ATOM   6653  O O   . GLY B 1 399 ? 133.620 64.559  128.975 1.00 25.75 ? 378  GLY B O   1 
ATOM   6654  N N   . GLY B 1 400 ? 134.429 62.709  129.974 1.00 24.27 ? 379  GLY B N   1 
ATOM   6655  C CA  . GLY B 1 400 ? 133.454 62.762  131.051 1.00 24.27 ? 379  GLY B CA  1 
ATOM   6656  C C   . GLY B 1 400 ? 132.043 62.598  130.528 1.00 24.27 ? 379  GLY B C   1 
ATOM   6657  O O   . GLY B 1 400 ? 131.789 61.854  129.575 1.00 24.27 ? 379  GLY B O   1 
ATOM   6658  N N   . GLU B 1 401 ? 131.103 63.303  131.157 1.00 30.84 ? 380  GLU B N   1 
ATOM   6659  C CA  . GLU B 1 401 ? 129.737 63.327  130.654 1.00 30.84 ? 380  GLU B CA  1 
ATOM   6660  C C   . GLU B 1 401 ? 129.621 64.373  129.554 1.00 30.84 ? 380  GLU B C   1 
ATOM   6661  O O   . GLU B 1 401 ? 128.715 65.210  129.568 1.00 30.84 ? 380  GLU B O   1 
ATOM   6662  C CB  . GLU B 1 401 ? 128.748 63.616  131.786 1.00 30.84 ? 380  GLU B CB  1 
ATOM   6663  C CG  . GLU B 1 401 ? 127.304 63.255  131.468 1.00 30.84 ? 380  GLU B CG  1 
ATOM   6664  C CD  . GLU B 1 401 ? 126.310 64.032  132.309 1.00 30.84 ? 380  GLU B CD  1 
ATOM   6665  O OE1 . GLU B 1 401 ? 125.441 64.713  131.728 1.00 30.84 ? 380  GLU B OE1 1 
ATOM   6666  O OE2 . GLU B 1 401 ? 126.396 63.961  133.552 1.00 30.84 ? 380  GLU B OE2 1 
ATOM   6667  N N   . LEU B 1 402 ? 130.557 64.337  128.606 1.00 25.70 ? 381  LEU B N   1 
ATOM   6668  C CA  . LEU B 1 402 ? 130.497 65.159  127.410 1.00 25.70 ? 381  LEU B CA  1 
ATOM   6669  C C   . LEU B 1 402 ? 130.968 64.412  126.174 1.00 25.70 ? 381  LEU B C   1 
ATOM   6670  O O   . LEU B 1 402 ? 131.051 65.022  125.104 1.00 25.70 ? 381  LEU B O   1 
ATOM   6671  C CB  . LEU B 1 402 ? 131.340 66.435  127.580 1.00 25.70 ? 381  LEU B CB  1 
ATOM   6672  C CG  . LEU B 1 402 ? 130.990 67.431  128.688 1.00 25.70 ? 381  LEU B CG  1 
ATOM   6673  C CD1 . LEU B 1 402 ? 132.035 68.526  128.744 1.00 25.70 ? 381  LEU B CD1 1 
ATOM   6674  C CD2 . LEU B 1 402 ? 129.616 68.026  128.466 1.00 25.70 ? 381  LEU B CD2 1 
ATOM   6675  N N   . SER B 1 403 ? 131.296 63.123  126.288 1.00 25.15 ? 382  SER B N   1 
ATOM   6676  C CA  . SER B 1 403 ? 131.804 62.380  125.139 1.00 25.15 ? 382  SER B CA  1 
ATOM   6677  C C   . SER B 1 403 ? 130.715 62.166  124.097 1.00 25.15 ? 382  SER B C   1 
ATOM   6678  O O   . SER B 1 403 ? 130.975 62.255  122.892 1.00 25.15 ? 382  SER B O   1 
ATOM   6679  C CB  . SER B 1 403 ? 132.385 61.044  125.598 1.00 25.15 ? 382  SER B CB  1 
ATOM   6680  O OG  . SER B 1 403 ? 133.301 61.232  126.661 1.00 25.15 ? 382  SER B OG  1 
ATOM   6681  N N   . GLY B 1 404 ? 129.495 61.883  124.539 1.00 21.60 ? 383  GLY B N   1 
ATOM   6682  C CA  . GLY B 1 404 ? 128.372 61.789  123.636 1.00 21.60 ? 383  GLY B CA  1 
ATOM   6683  C C   . GLY B 1 404 ? 127.834 63.117  123.165 1.00 21.60 ? 383  GLY B C   1 
ATOM   6684  O O   . GLY B 1 404 ? 126.911 63.153  122.347 1.00 21.60 ? 383  GLY B O   1 
ATOM   6685  N N   . GLY B 1 405 ? 128.388 64.216  123.665 1.00 20.42 ? 384  GLY B N   1 
ATOM   6686  C CA  . GLY B 1 405 ? 127.998 65.527  123.202 1.00 20.42 ? 384  GLY B CA  1 
ATOM   6687  C C   . GLY B 1 405 ? 128.482 65.796  121.794 1.00 20.42 ? 384  GLY B C   1 
ATOM   6688  O O   . GLY B 1 405 ? 129.236 65.031  121.194 1.00 20.42 ? 384  GLY B O   1 
ATOM   6689  N N   . TYR B 1 406 ? 128.028 66.918  121.253 1.00 22.12 ? 385  TYR B N   1 
ATOM   6690  C CA  . TYR B 1 406 ? 128.331 67.308  119.881 1.00 22.12 ? 385  TYR B CA  1 
ATOM   6691  C C   . TYR B 1 406 ? 129.219 68.548  119.916 1.00 22.12 ? 385  TYR B C   1 
ATOM   6692  O O   . TYR B 1 406 ? 128.725 69.670  120.041 1.00 22.12 ? 385  TYR B O   1 
ATOM   6693  C CB  . TYR B 1 406 ? 127.042 67.540  119.101 1.00 22.12 ? 385  TYR B CB  1 
ATOM   6694  C CG  . TYR B 1 406 ? 126.109 66.352  119.152 1.00 22.12 ? 385  TYR B CG  1 
ATOM   6695  C CD1 . TYR B 1 406 ? 126.493 65.121  118.638 1.00 22.12 ? 385  TYR B CD1 1 
ATOM   6696  C CD2 . TYR B 1 406 ? 124.853 66.454  119.727 1.00 22.12 ? 385  TYR B CD2 1 
ATOM   6697  C CE1 . TYR B 1 406 ? 125.650 64.031  118.685 1.00 22.12 ? 385  TYR B CE1 1 
ATOM   6698  C CE2 . TYR B 1 406 ? 124.002 65.368  119.781 1.00 22.12 ? 385  TYR B CE2 1 
ATOM   6699  C CZ  . TYR B 1 406 ? 124.407 64.158  119.257 1.00 22.12 ? 385  TYR B CZ  1 
ATOM   6700  O OH  . TYR B 1 406 ? 123.565 63.071  119.306 1.00 22.12 ? 385  TYR B OH  1 
ATOM   6701  N N   . TYR B 1 407 ? 130.531 68.344  119.791 1.00 21.09 ? 386  TYR B N   1 
ATOM   6702  C CA  . TYR B 1 407 ? 131.510 69.415  119.949 1.00 21.09 ? 386  TYR B CA  1 
ATOM   6703  C C   . TYR B 1 407 ? 132.525 69.349  118.818 1.00 21.09 ? 386  TYR B C   1 
ATOM   6704  O O   . TYR B 1 407 ? 133.142 68.304  118.599 1.00 21.09 ? 386  TYR B O   1 
ATOM   6705  C CB  . TYR B 1 407 ? 132.220 69.305  121.301 1.00 21.09 ? 386  TYR B CB  1 
ATOM   6706  C CG  . TYR B 1 407 ? 131.316 69.496  122.492 1.00 21.09 ? 386  TYR B CG  1 
ATOM   6707  C CD1 . TYR B 1 407 ? 131.108 70.753  123.034 1.00 21.09 ? 386  TYR B CD1 1 
ATOM   6708  C CD2 . TYR B 1 407 ? 130.668 68.419  123.073 1.00 21.09 ? 386  TYR B CD2 1 
ATOM   6709  C CE1 . TYR B 1 407 ? 130.284 70.931  124.120 1.00 21.09 ? 386  TYR B CE1 1 
ATOM   6710  C CE2 . TYR B 1 407 ? 129.840 68.588  124.160 1.00 21.09 ? 386  TYR B CE2 1 
ATOM   6711  C CZ  . TYR B 1 407 ? 129.651 69.847  124.679 1.00 21.09 ? 386  TYR B CZ  1 
ATOM   6712  O OH  . TYR B 1 407 ? 128.825 70.023  125.762 1.00 21.09 ? 386  TYR B OH  1 
ATOM   6713  N N   . ILE B 1 408 ? 132.706 70.466  118.117 1.00 22.01 ? 387  ILE B N   1 
ATOM   6714  C CA  . ILE B 1 408 ? 133.736 70.618  117.097 1.00 22.01 ? 387  ILE B CA  1 
ATOM   6715  C C   . ILE B 1 408 ? 134.610 71.809  117.465 1.00 22.01 ? 387  ILE B C   1 
ATOM   6716  O O   . ILE B 1 408 ? 134.103 72.855  117.881 1.00 22.01 ? 387  ILE B O   1 
ATOM   6717  C CB  . ILE B 1 408 ? 133.128 70.795  115.691 1.00 22.01 ? 387  ILE B CB  1 
ATOM   6718  C CG1 . ILE B 1 408 ? 132.374 69.530  115.284 1.00 22.01 ? 387  ILE B CG1 1 
ATOM   6719  C CG2 . ILE B 1 408 ? 134.201 71.123  114.670 1.00 22.01 ? 387  ILE B CG2 1 
ATOM   6720  C CD1 . ILE B 1 408 ? 131.542 69.691  114.052 1.00 22.01 ? 387  ILE B CD1 1 
ATOM   6721  N N   . GLU B 1 409 ? 135.921 71.642  117.316 1.00 23.38 ? 388  GLU B N   1 
ATOM   6722  C CA  . GLU B 1 409 ? 136.860 72.685  117.697 1.00 23.38 ? 388  GLU B CA  1 
ATOM   6723  C C   . GLU B 1 409 ? 136.771 73.865  116.731 1.00 23.38 ? 388  GLU B C   1 
ATOM   6724  O O   . GLU B 1 409 ? 136.679 73.664  115.517 1.00 23.38 ? 388  GLU B O   1 
ATOM   6725  C CB  . GLU B 1 409 ? 138.285 72.138  117.705 1.00 23.38 ? 388  GLU B CB  1 
ATOM   6726  C CG  . GLU B 1 409 ? 138.747 71.603  119.043 1.00 23.38 ? 388  GLU B CG  1 
ATOM   6727  C CD  . GLU B 1 409 ? 139.982 70.735  118.920 1.00 23.38 ? 388  GLU B CD  1 
ATOM   6728  O OE1 . GLU B 1 409 ? 140.085 69.732  119.657 1.00 23.38 ? 388  GLU B OE1 1 
ATOM   6729  O OE2 . GLU B 1 409 ? 140.851 71.054  118.084 1.00 23.38 ? 388  GLU B OE2 1 
ATOM   6730  N N   . PRO B 1 410 ? 136.788 75.109  117.242 1.00 17.74 ? 389  PRO B N   1 
ATOM   6731  C CA  . PRO B 1 410 ? 136.864 76.277  116.353 1.00 17.74 ? 389  PRO B CA  1 
ATOM   6732  C C   . PRO B 1 410 ? 138.041 76.207  115.393 1.00 17.74 ? 389  PRO B C   1 
ATOM   6733  O O   . PRO B 1 410 ? 139.178 75.964  115.807 1.00 17.74 ? 389  PRO B O   1 
ATOM   6734  C CB  . PRO B 1 410 ? 137.002 77.446  117.333 1.00 17.74 ? 389  PRO B CB  1 
ATOM   6735  C CG  . PRO B 1 410 ? 136.280 76.985  118.541 1.00 17.74 ? 389  PRO B CG  1 
ATOM   6736  C CD  . PRO B 1 410 ? 136.511 75.497  118.635 1.00 17.74 ? 389  PRO B CD  1 
ATOM   6737  N N   . THR B 1 411 ? 137.776 76.428  114.109 1.00 19.78 ? 390  THR B N   1 
ATOM   6738  C CA  . THR B 1 411 ? 138.730 76.152  113.048 1.00 19.78 ? 390  THR B CA  1 
ATOM   6739  C C   . THR B 1 411 ? 138.963 77.396  112.201 1.00 19.78 ? 390  THR B C   1 
ATOM   6740  O O   . THR B 1 411 ? 138.045 78.183  111.959 1.00 19.78 ? 390  THR B O   1 
ATOM   6741  C CB  . THR B 1 411 ? 138.226 75.007  112.158 1.00 19.78 ? 390  THR B CB  1 
ATOM   6742  O OG1 . THR B 1 411 ? 137.949 73.861  112.969 1.00 19.78 ? 390  THR B OG1 1 
ATOM   6743  C CG2 . THR B 1 411 ? 139.259 74.632  111.112 1.00 19.78 ? 390  THR B CG2 1 
ATOM   6744  N N   . ILE B 1 412 ? 140.209 77.569  111.761 1.00 21.13 ? 391  ILE B N   1 
ATOM   6745  C CA  . ILE B 1 412 ? 140.582 78.588  110.787 1.00 21.13 ? 391  ILE B CA  1 
ATOM   6746  C C   . ILE B 1 412 ? 141.399 77.911  109.698 1.00 21.13 ? 391  ILE B C   1 
ATOM   6747  O O   . ILE B 1 412 ? 142.423 77.280  109.995 1.00 21.13 ? 391  ILE B O   1 
ATOM   6748  C CB  . ILE B 1 412 ? 141.393 79.736  111.413 1.00 21.13 ? 391  ILE B CB  1 
ATOM   6749  C CG1 . ILE B 1 412 ? 140.708 80.286  112.657 1.00 21.13 ? 391  ILE B CG1 1 
ATOM   6750  C CG2 . ILE B 1 412 ? 141.579 80.853  110.411 1.00 21.13 ? 391  ILE B CG2 1 
ATOM   6751  C CD1 . ILE B 1 412 ? 141.529 81.323  113.359 1.00 21.13 ? 391  ILE B CD1 1 
ATOM   6752  N N   . PHE B 1 413 ? 140.944 78.041  108.448 1.00 25.58 ? 392  PHE B N   1 
ATOM   6753  C CA  . PHE B 1 413 ? 141.658 77.639  107.247 1.00 25.58 ? 392  PHE B CA  1 
ATOM   6754  C C   . PHE B 1 413 ? 142.299 78.853  106.582 1.00 25.58 ? 392  PHE B C   1 
ATOM   6755  O O   . PHE B 1 413 ? 142.309 79.960  107.126 1.00 25.58 ? 392  PHE B O   1 
ATOM   6756  C CB  . PHE B 1 413 ? 140.732 76.939  106.248 1.00 25.58 ? 392  PHE B CB  1 
ATOM   6757  C CG  . PHE B 1 413 ? 140.026 75.740  106.792 1.00 25.58 ? 392  PHE B CG  1 
ATOM   6758  C CD1 . PHE B 1 413 ? 140.606 74.490  106.701 1.00 25.58 ? 392  PHE B CD1 1 
ATOM   6759  C CD2 . PHE B 1 413 ? 138.769 75.850  107.352 1.00 25.58 ? 392  PHE B CD2 1 
ATOM   6760  C CE1 . PHE B 1 413 ? 139.964 73.379  107.185 1.00 25.58 ? 392  PHE B CE1 1 
ATOM   6761  C CE2 . PHE B 1 413 ? 138.120 74.738  107.834 1.00 25.58 ? 392  PHE B CE2 1 
ATOM   6762  C CZ  . PHE B 1 413 ? 138.717 73.503  107.753 1.00 25.58 ? 392  PHE B CZ  1 
ATOM   6763  N N   . ARG B 1 414 ? 142.834 78.644  105.381 1.00 26.07 ? 393  ARG B N   1 
ATOM   6764  C CA  . ARG B 1 414 ? 143.380 79.730  104.571 1.00 26.07 ? 393  ARG B CA  1 
ATOM   6765  C C   . ARG B 1 414 ? 143.441 79.276  103.124 1.00 26.07 ? 393  ARG B C   1 
ATOM   6766  O O   . ARG B 1 414 ? 144.143 78.310  102.813 1.00 26.07 ? 393  ARG B O   1 
ATOM   6767  C CB  . ARG B 1 414 ? 144.763 80.138  105.061 1.00 26.07 ? 393  ARG B CB  1 
ATOM   6768  C CG  . ARG B 1 414 ? 145.520 80.985  104.064 1.00 26.07 ? 393  ARG B CG  1 
ATOM   6769  C CD  . ARG B 1 414 ? 146.442 81.964  104.758 1.00 26.07 ? 393  ARG B CD  1 
ATOM   6770  N NE  . ARG B 1 414 ? 147.591 82.334  103.935 1.00 26.07 ? 393  ARG B NE  1 
ATOM   6771  C CZ  . ARG B 1 414 ? 147.521 82.991  102.780 1.00 26.07 ? 393  ARG B CZ  1 
ATOM   6772  N NH1 . ARG B 1 414 ? 146.350 83.383  102.295 1.00 26.07 ? 393  ARG B NH1 1 
ATOM   6773  N NH2 . ARG B 1 414 ? 148.632 83.271  102.114 1.00 26.07 ? 393  ARG B NH2 1 
ATOM   6774  N N   . GLY B 1 415 ? 142.725 79.963  102.248 1.00 25.21 ? 394  GLY B N   1 
ATOM   6775  C CA  . GLY B 1 415 ? 142.719 79.645  100.830 1.00 25.21 ? 394  GLY B CA  1 
ATOM   6776  C C   . GLY B 1 415 ? 142.360 80.856  99.998  1.00 25.21 ? 394  GLY B C   1 
ATOM   6777  O O   . GLY B 1 415 ? 142.601 81.995  100.406 1.00 25.21 ? 394  GLY B O   1 
ATOM   6778  N N   . ASN B 1 416 ? 141.802 80.610  98.814  1.00 27.41 ? 395  ASN B N   1 
ATOM   6779  C CA  . ASN B 1 416 ? 141.295 81.661  97.947  1.00 27.41 ? 395  ASN B CA  1 
ATOM   6780  C C   . ASN B 1 416 ? 139.806 81.453  97.712  1.00 27.41 ? 395  ASN B C   1 
ATOM   6781  O O   . ASN B 1 416 ? 139.269 80.363  97.920  1.00 27.41 ? 395  ASN B O   1 
ATOM   6782  C CB  . ASN B 1 416 ? 142.050 81.714  96.610  1.00 27.41 ? 395  ASN B CB  1 
ATOM   6783  C CG  . ASN B 1 416 ? 142.069 80.382  95.888  1.00 27.41 ? 395  ASN B CG  1 
ATOM   6784  O OD1 . ASN B 1 416 ? 142.900 79.520  96.174  1.00 27.41 ? 395  ASN B OD1 1 
ATOM   6785  N ND2 . ASN B 1 416 ? 141.161 80.212  94.935  1.00 27.41 ? 395  ASN B ND2 1 
ATOM   6786  N N   . ASN B 1 417 ? 139.145 82.511  97.247  1.00 23.76 ? 396  ASN B N   1 
ATOM   6787  C CA  . ASN B 1 417 ? 137.688 82.594  97.275  1.00 23.76 ? 396  ASN B CA  1 
ATOM   6788  C C   . ASN B 1 417 ? 137.004 81.584  96.361  1.00 23.76 ? 396  ASN B C   1 
ATOM   6789  O O   . ASN B 1 417 ? 135.787 81.399  96.443  1.00 23.76 ? 396  ASN B O   1 
ATOM   6790  C CB  . ASN B 1 417 ? 137.236 84.004  96.899  1.00 23.76 ? 396  ASN B CB  1 
ATOM   6791  C CG  . ASN B 1 417 ? 136.001 84.433  97.648  1.00 23.76 ? 396  ASN B CG  1 
ATOM   6792  O OD1 . ASN B 1 417 ? 135.734 83.956  98.749  1.00 23.76 ? 396  ASN B OD1 1 
ATOM   6793  N ND2 . ASN B 1 417 ? 135.224 85.322  97.048  1.00 23.76 ? 396  ASN B ND2 1 
ATOM   6794  N N   . LYS B 1 418 ? 137.766 80.929  95.484  1.00 30.82 ? 397  LYS B N   1 
ATOM   6795  C CA  . LYS B 1 418 ? 137.218 79.947  94.556  1.00 30.82 ? 397  LYS B CA  1 
ATOM   6796  C C   . LYS B 1 418 ? 137.211 78.540  95.143  1.00 30.82 ? 397  LYS B C   1 
ATOM   6797  O O   . LYS B 1 418 ? 137.262 77.556  94.400  1.00 30.82 ? 397  LYS B O   1 
ATOM   6798  C CB  . LYS B 1 418 ? 137.993 79.968  93.239  1.00 30.82 ? 397  LYS B CB  1 
ATOM   6799  C CG  . LYS B 1 418 ? 137.952 81.301  92.514  1.00 30.82 ? 397  LYS B CG  1 
ATOM   6800  C CD  . LYS B 1 418 ? 136.522 81.764  92.280  1.00 30.82 ? 397  LYS B CD  1 
ATOM   6801  C CE  . LYS B 1 418 ? 135.787 80.846  91.315  1.00 30.82 ? 397  LYS B CE  1 
ATOM   6802  N NZ  . LYS B 1 418 ? 134.400 81.318  91.041  1.00 30.82 ? 397  LYS B NZ  1 
ATOM   6803  N N   . MET B 1 419 ? 137.144 78.429  96.464  1.00 30.70 ? 398  MET B N   1 
ATOM   6804  C CA  . MET B 1 419 ? 137.158 77.148  97.151  1.00 30.70 ? 398  MET B CA  1 
ATOM   6805  C C   . MET B 1 419 ? 135.871 76.974  97.947  1.00 30.70 ? 398  MET B C   1 
ATOM   6806  O O   . MET B 1 419 ? 135.298 77.943  98.454  1.00 30.70 ? 398  MET B O   1 
ATOM   6807  C CB  . MET B 1 419 ? 138.383 77.032  98.057  1.00 30.70 ? 398  MET B CB  1 
ATOM   6808  C CG  . MET B 1 419 ? 139.696 77.152  97.294  1.00 30.70 ? 398  MET B CG  1 
ATOM   6809  S SD  . MET B 1 419 ? 141.059 77.721  98.319  1.00 30.70 ? 398  MET B SD  1 
ATOM   6810  C CE  . MET B 1 419 ? 140.674 76.880  99.843  1.00 30.70 ? 398  MET B CE  1 
ATOM   6811  N N   . ARG B 1 420 ? 135.426 75.719  98.048  1.00 28.39 ? 399  ARG B N   1 
ATOM   6812  C CA  . ARG B 1 420 ? 134.071 75.434  98.511  1.00 28.39 ? 399  ARG B CA  1 
ATOM   6813  C C   . ARG B 1 420 ? 133.827 75.918  99.931  1.00 28.39 ? 399  ARG B C   1 
ATOM   6814  O O   . ARG B 1 420 ? 132.688 76.243  100.285 1.00 28.39 ? 399  ARG B O   1 
ATOM   6815  C CB  . ARG B 1 420 ? 133.794 73.936  98.413  1.00 28.39 ? 399  ARG B CB  1 
ATOM   6816  C CG  . ARG B 1 420 ? 134.170 73.330  97.079  1.00 28.39 ? 399  ARG B CG  1 
ATOM   6817  C CD  . ARG B 1 420 ? 132.943 73.114  96.209  1.00 28.39 ? 399  ARG B CD  1 
ATOM   6818  N NE  . ARG B 1 420 ? 131.982 72.201  96.825  1.00 28.39 ? 399  ARG B NE  1 
ATOM   6819  C CZ  . ARG B 1 420 ? 132.169 70.893  96.976  1.00 28.39 ? 399  ARG B CZ  1 
ATOM   6820  N NH1 . ARG B 1 420 ? 133.288 70.320  96.556  1.00 28.39 ? 399  ARG B NH1 1 
ATOM   6821  N NH2 . ARG B 1 420 ? 131.231 70.155  97.550  1.00 28.39 ? 399  ARG B NH2 1 
ATOM   6822  N N   . ILE B 1 421 ? 134.868 75.967  100.762 1.00 26.72 ? 400  ILE B N   1 
ATOM   6823  C CA  . ILE B 1 421 ? 134.684 76.427  102.134 1.00 26.72 ? 400  ILE B CA  1 
ATOM   6824  C C   . ILE B 1 421 ? 134.320 77.903  102.145 1.00 26.72 ? 400  ILE B C   1 
ATOM   6825  O O   . ILE B 1 421 ? 133.592 78.370  103.030 1.00 26.72 ? 400  ILE B O   1 
ATOM   6826  C CB  . ILE B 1 421 ? 135.950 76.140  102.956 1.00 26.72 ? 400  ILE B CB  1 
ATOM   6827  C CG1 . ILE B 1 421 ? 136.281 74.660  102.858 1.00 26.72 ? 400  ILE B CG1 1 
ATOM   6828  C CG2 . ILE B 1 421 ? 135.729 76.484  104.411 1.00 26.72 ? 400  ILE B CG2 1 
ATOM   6829  C CD1 . ILE B 1 421 ? 135.190 73.777  103.375 1.00 26.72 ? 400  ILE B CD1 1 
ATOM   6830  N N   . PHE B 1 422 ? 134.811 78.656  101.163 1.00 25.02 ? 401  PHE B N   1 
ATOM   6831  C CA  . PHE B 1 422 ? 134.402 80.042  100.996 1.00 25.02 ? 401  PHE B CA  1 
ATOM   6832  C C   . PHE B 1 422 ? 133.002 80.160  100.410 1.00 25.02 ? 401  PHE B C   1 
ATOM   6833  O O   . PHE B 1 422 ? 132.280 81.107  100.734 1.00 25.02 ? 401  PHE B O   1 
ATOM   6834  C CB  . PHE B 1 422 ? 135.391 80.773  100.089 1.00 25.02 ? 401  PHE B CB  1 
ATOM   6835  C CG  . PHE B 1 422 ? 136.697 81.096  100.747 1.00 25.02 ? 401  PHE B CG  1 
ATOM   6836  C CD1 . PHE B 1 422 ? 136.840 82.243  101.505 1.00 25.02 ? 401  PHE B CD1 1 
ATOM   6837  C CD2 . PHE B 1 422 ? 137.786 80.256  100.599 1.00 25.02 ? 401  PHE B CD2 1 
ATOM   6838  C CE1 . PHE B 1 422 ? 138.042 82.546  102.101 1.00 25.02 ? 401  PHE B CE1 1 
ATOM   6839  C CE2 . PHE B 1 422 ? 138.991 80.553  101.194 1.00 25.02 ? 401  PHE B CE2 1 
ATOM   6840  C CZ  . PHE B 1 422 ? 139.121 81.699  101.946 1.00 25.02 ? 401  PHE B CZ  1 
ATOM   6841  N N   . GLN B 1 423 ? 132.600 79.220  99.551  1.00 24.77 ? 402  GLN B N   1 
ATOM   6842  C CA  . GLN B 1 423 ? 131.387 79.374  98.756  1.00 24.77 ? 402  GLN B CA  1 
ATOM   6843  C C   . GLN B 1 423 ? 130.285 78.390  99.138  1.00 24.77 ? 402  GLN B C   1 
ATOM   6844  O O   . GLN B 1 423 ? 129.391 78.129  98.327  1.00 24.77 ? 402  GLN B O   1 
ATOM   6845  C CB  . GLN B 1 423 ? 131.714 79.248  97.268  1.00 24.77 ? 402  GLN B CB  1 
ATOM   6846  C CG  . GLN B 1 423 ? 132.186 80.546  96.623  1.00 24.77 ? 402  GLN B CG  1 
ATOM   6847  C CD  . GLN B 1 423 ? 131.449 81.771  97.136  1.00 24.77 ? 402  GLN B CD  1 
ATOM   6848  O OE1 . GLN B 1 423 ? 130.222 81.775  97.253  1.00 24.77 ? 402  GLN B OE1 1 
ATOM   6849  N NE2 . GLN B 1 423 ? 132.198 82.821  97.445  1.00 24.77 ? 402  GLN B NE2 1 
ATOM   6850  N N   . GLU B 1 424 ? 130.328 77.832  100.347 1.00 28.00 ? 403  GLU B N   1 
ATOM   6851  C CA  . GLU B 1 424 ? 129.211 77.081  100.905 1.00 28.00 ? 403  GLU B CA  1 
ATOM   6852  C C   . GLU B 1 424 ? 129.129 77.331  102.401 1.00 28.00 ? 403  GLU B C   1 
ATOM   6853  O O   . GLU B 1 424 ? 130.154 77.385  103.083 1.00 28.00 ? 403  GLU B O   1 
ATOM   6854  C CB  . GLU B 1 424 ? 129.317 75.571  100.637 1.00 28.00 ? 403  GLU B CB  1 
ATOM   6855  C CG  . GLU B 1 424 ? 128.715 75.105  99.310  1.00 28.00 ? 403  GLU B CG  1 
ATOM   6856  C CD  . GLU B 1 424 ? 129.716 75.030  98.177  1.00 28.00 ? 403  GLU B CD  1 
ATOM   6857  O OE1 . GLU B 1 424 ? 130.916 75.245  98.424  1.00 28.00 ? 403  GLU B OE1 1 
ATOM   6858  O OE2 . GLU B 1 424 ? 129.299 74.756  97.034  1.00 28.00 ? 403  GLU B OE2 1 
ATOM   6859  N N   . GLU B 1 425 ? 127.906 77.489  102.899 1.00 25.56 ? 404  GLU B N   1 
ATOM   6860  C CA  . GLU B 1 425 ? 127.680 77.726  104.319 1.00 25.56 ? 404  GLU B CA  1 
ATOM   6861  C C   . GLU B 1 425 ? 127.870 76.438  105.115 1.00 25.56 ? 404  GLU B C   1 
ATOM   6862  O O   . GLU B 1 425 ? 127.545 75.347  104.640 1.00 25.56 ? 404  GLU B O   1 
ATOM   6863  C CB  . GLU B 1 425 ? 126.272 78.275  104.528 1.00 25.56 ? 404  GLU B CB  1 
ATOM   6864  C CG  . GLU B 1 425 ? 126.141 79.253  105.669 1.00 25.56 ? 404  GLU B CG  1 
ATOM   6865  C CD  . GLU B 1 425 ? 124.720 79.739  105.838 1.00 25.56 ? 404  GLU B CD  1 
ATOM   6866  O OE1 . GLU B 1 425 ? 123.836 79.255  105.101 1.00 25.56 ? 404  GLU B OE1 1 
ATOM   6867  O OE2 . GLU B 1 425 ? 124.490 80.624  106.688 1.00 25.56 ? 404  GLU B OE2 1 
ATOM   6868  N N   . ILE B 1 426 ? 128.397 76.564  106.335 1.00 21.86 ? 405  ILE B N   1 
ATOM   6869  C CA  . ILE B 1 426 ? 128.719 75.383  107.133 1.00 21.86 ? 405  ILE B CA  1 
ATOM   6870  C C   . ILE B 1 426 ? 127.902 75.332  108.422 1.00 21.86 ? 405  ILE B C   1 
ATOM   6871  O O   . ILE B 1 426 ? 127.554 74.245  108.899 1.00 21.86 ? 405  ILE B O   1 
ATOM   6872  C CB  . ILE B 1 426 ? 130.229 75.319  107.449 1.00 21.86 ? 405  ILE B CB  1 
ATOM   6873  C CG1 . ILE B 1 426 ? 131.068 75.212  106.174 1.00 21.86 ? 405  ILE B CG1 1 
ATOM   6874  C CG2 . ILE B 1 426 ? 130.555 74.139  108.337 1.00 21.86 ? 405  ILE B CG2 1 
ATOM   6875  C CD1 . ILE B 1 426 ? 131.566 76.526  105.650 1.00 21.86 ? 405  ILE B CD1 1 
ATOM   6876  N N   . PHE B 1 427 ? 127.564 76.496  108.979 1.00 19.59 ? 406  PHE B N   1 
ATOM   6877  C CA  . PHE B 1 427 ? 127.058 76.618  110.349 1.00 19.59 ? 406  PHE B CA  1 
ATOM   6878  C C   . PHE B 1 427 ? 128.011 76.038  111.386 1.00 19.59 ? 406  PHE B C   1 
ATOM   6879  O O   . PHE B 1 427 ? 127.581 75.653  112.477 1.00 19.59 ? 406  PHE B O   1 
ATOM   6880  C CB  . PHE B 1 427 ? 125.677 75.979  110.536 1.00 19.59 ? 406  PHE B CB  1 
ATOM   6881  C CG  . PHE B 1 427 ? 124.566 76.692  109.840 1.00 19.59 ? 406  PHE B CG  1 
ATOM   6882  C CD1 . PHE B 1 427 ? 124.737 77.969  109.357 1.00 19.59 ? 406  PHE B CD1 1 
ATOM   6883  C CD2 . PHE B 1 427 ? 123.328 76.095  109.716 1.00 19.59 ? 406  PHE B CD2 1 
ATOM   6884  C CE1 . PHE B 1 427 ? 123.705 78.628  108.737 1.00 19.59 ? 406  PHE B CE1 1 
ATOM   6885  C CE2 . PHE B 1 427 ? 122.287 76.749  109.091 1.00 19.59 ? 406  PHE B CE2 1 
ATOM   6886  C CZ  . PHE B 1 427 ? 122.478 78.020  108.598 1.00 19.59 ? 406  PHE B CZ  1 
ATOM   6887  N N   . GLY B 1 428 ? 129.301 75.970  111.083 1.00 16.62 ? 407  GLY B N   1 
ATOM   6888  C CA  . GLY B 1 428 ? 130.263 75.469  112.033 1.00 16.62 ? 407  GLY B CA  1 
ATOM   6889  C C   . GLY B 1 428 ? 131.088 76.576  112.646 1.00 16.62 ? 407  GLY B C   1 
ATOM   6890  O O   . GLY B 1 428 ? 131.103 77.709  112.159 1.00 16.62 ? 407  GLY B O   1 
ATOM   6891  N N   . PRO B 1 429 ? 131.791 76.274  113.733 1.00 16.34 ? 408  PRO B N   1 
ATOM   6892  C CA  . PRO B 1 429 ? 132.776 77.227  114.270 1.00 16.34 ? 408  PRO B CA  1 
ATOM   6893  C C   . PRO B 1 429 ? 134.018 77.293  113.389 1.00 16.34 ? 408  PRO B C   1 
ATOM   6894  O O   . PRO B 1 429 ? 135.136 76.999  113.810 1.00 16.34 ? 408  PRO B O   1 
ATOM   6895  C CB  . PRO B 1 429 ? 133.059 76.654  115.664 1.00 16.34 ? 408  PRO B CB  1 
ATOM   6896  C CG  . PRO B 1 429 ? 132.849 75.206  115.511 1.00 16.34 ? 408  PRO B CG  1 
ATOM   6897  C CD  . PRO B 1 429 ? 131.718 75.044  114.536 1.00 16.34 ? 408  PRO B CD  1 
ATOM   6898  N N   . VAL B 1 430 ? 133.809 77.679  112.135 1.00 16.38 ? 409  VAL B N   1 
ATOM   6899  C CA  . VAL B 1 430 ? 134.824 77.615  111.096 1.00 16.38 ? 409  VAL B CA  1 
ATOM   6900  C C   . VAL B 1 430 ? 134.878 78.956  110.388 1.00 16.38 ? 409  VAL B C   1 
ATOM   6901  O O   . VAL B 1 430 ? 133.842 79.590  110.161 1.00 16.38 ? 409  VAL B O   1 
ATOM   6902  C CB  . VAL B 1 430 ? 134.521 76.481  110.098 1.00 16.38 ? 409  VAL B CB  1 
ATOM   6903  C CG1 . VAL B 1 430 ? 135.486 76.515  108.940 1.00 16.38 ? 409  VAL B CG1 1 
ATOM   6904  C CG2 . VAL B 1 430 ? 134.588 75.146  110.797 1.00 16.38 ? 409  VAL B CG2 1 
ATOM   6905  N N   . VAL B 1 431 ? 136.088 79.394  110.047 1.00 16.55 ? 410  VAL B N   1 
ATOM   6906  C CA  . VAL B 1 431 ? 136.291 80.634  109.315 1.00 16.55 ? 410  VAL B CA  1 
ATOM   6907  C C   . VAL B 1 431 ? 137.408 80.416  108.304 1.00 16.55 ? 410  VAL B C   1 
ATOM   6908  O O   . VAL B 1 431 ? 138.336 79.635  108.533 1.00 16.55 ? 410  VAL B O   1 
ATOM   6909  C CB  . VAL B 1 431 ? 136.617 81.805  110.267 1.00 16.55 ? 410  VAL B CB  1 
ATOM   6910  C CG1 . VAL B 1 431 ? 137.952 81.588  110.926 1.00 16.55 ? 410  VAL B CG1 1 
ATOM   6911  C CG2 . VAL B 1 431 ? 136.593 83.115  109.533 1.00 16.55 ? 410  VAL B CG2 1 
ATOM   6912  N N   . SER B 1 432 ? 137.302 81.097  107.168 1.00 17.41 ? 411  SER B N   1 
ATOM   6913  C CA  . SER B 1 432 ? 138.305 81.031  106.119 1.00 17.41 ? 411  SER B CA  1 
ATOM   6914  C C   . SER B 1 432 ? 138.894 82.416  105.896 1.00 17.41 ? 411  SER B C   1 
ATOM   6915  O O   . SER B 1 432 ? 138.201 83.429  106.019 1.00 17.41 ? 411  SER B O   1 
ATOM   6916  C CB  . SER B 1 432 ? 137.712 80.494  104.817 1.00 17.41 ? 411  SER B CB  1 
ATOM   6917  O OG  . SER B 1 432 ? 136.994 79.297  105.041 1.00 17.41 ? 411  SER B OG  1 
ATOM   6918  N N   . VAL B 1 433 ? 140.182 82.450  105.562 1.00 16.63 ? 412  VAL B N   1 
ATOM   6919  C CA  . VAL B 1 433 ? 140.951 83.685  105.500 1.00 16.63 ? 412  VAL B CA  1 
ATOM   6920  C C   . VAL B 1 433 ? 141.617 83.789  104.137 1.00 16.63 ? 412  VAL B C   1 
ATOM   6921  O O   . VAL B 1 433 ? 142.246 82.831  103.674 1.00 16.63 ? 412  VAL B O   1 
ATOM   6922  C CB  . VAL B 1 433 ? 142.006 83.746  106.619 1.00 16.63 ? 412  VAL B CB  1 
ATOM   6923  C CG1 . VAL B 1 433 ? 143.028 84.821  106.327 1.00 16.63 ? 412  VAL B CG1 1 
ATOM   6924  C CG2 . VAL B 1 433 ? 141.342 83.989  107.959 1.00 16.63 ? 412  VAL B CG2 1 
ATOM   6925  N N   . THR B 1 434 ? 141.472 84.946  103.494 1.00 15.26 ? 413  THR B N   1 
ATOM   6926  C CA  . THR B 1 434 ? 142.222 85.273  102.290 1.00 15.26 ? 413  THR B CA  1 
ATOM   6927  C C   . THR B 1 434 ? 142.456 86.776  102.260 1.00 15.26 ? 413  THR B C   1 
ATOM   6928  O O   . THR B 1 434 ? 141.816 87.537  102.987 1.00 15.26 ? 413  THR B O   1 
ATOM   6929  C CB  . THR B 1 434 ? 141.509 84.800  101.022 1.00 15.26 ? 413  THR B CB  1 
ATOM   6930  O OG1 . THR B 1 434 ? 142.366 84.997  99.893  1.00 15.26 ? 413  THR B OG1 1 
ATOM   6931  C CG2 . THR B 1 434 ? 140.226 85.549  100.807 1.00 15.26 ? 413  THR B CG2 1 
ATOM   6932  N N   . THR B 1 435 ? 143.385 87.198  101.411 1.00 13.66 ? 414  THR B N   1 
ATOM   6933  C CA  . THR B 1 435 ? 143.859 88.574  101.391 1.00 13.66 ? 414  THR B CA  1 
ATOM   6934  C C   . THR B 1 435 ? 143.472 89.264  100.088 1.00 13.66 ? 414  THR B C   1 
ATOM   6935  O O   . THR B 1 435 ? 142.959 88.646  99.152  1.00 13.66 ? 414  THR B O   1 
ATOM   6936  C CB  . THR B 1 435 ? 145.378 88.628  101.576 1.00 13.66 ? 414  THR B CB  1 
ATOM   6937  O OG1 . THR B 1 435 ? 146.015 88.024  100.447 1.00 13.66 ? 414  THR B OG1 1 
ATOM   6938  C CG2 . THR B 1 435 ? 145.782 87.882  102.829 1.00 13.66 ? 414  THR B CG2 1 
ATOM   6939  N N   . PHE B 1 436 ? 143.731 90.569  100.040 1.00 12.55 ? 415  PHE B N   1 
ATOM   6940  C CA  . PHE B 1 436 ? 143.465 91.379  98.861  1.00 12.55 ? 415  PHE B CA  1 
ATOM   6941  C C   . PHE B 1 436 ? 144.516 92.474  98.756  1.00 12.55 ? 415  PHE B C   1 
ATOM   6942  O O   . PHE B 1 436 ? 145.340 92.664  99.653  1.00 12.55 ? 415  PHE B O   1 
ATOM   6943  C CB  . PHE B 1 436 ? 142.058 91.984  98.892  1.00 12.55 ? 415  PHE B CB  1 
ATOM   6944  C CG  . PHE B 1 436 ? 141.780 92.837  100.096 1.00 12.55 ? 415  PHE B CG  1 
ATOM   6945  C CD1 . PHE B 1 436 ? 141.256 92.285  101.244 1.00 12.55 ? 415  PHE B CD1 1 
ATOM   6946  C CD2 . PHE B 1 436 ? 142.018 94.197  100.068 1.00 12.55 ? 415  PHE B CD2 1 
ATOM   6947  C CE1 . PHE B 1 436 ? 140.990 93.070  102.340 1.00 12.55 ? 415  PHE B CE1 1 
ATOM   6948  C CE2 . PHE B 1 436 ? 141.750 94.984  101.162 1.00 12.55 ? 415  PHE B CE2 1 
ATOM   6949  C CZ  . PHE B 1 436 ? 141.238 94.420  102.299 1.00 12.55 ? 415  PHE B CZ  1 
ATOM   6950  N N   . LYS B 1 437 ? 144.484 93.200  97.640  1.00 15.05 ? 416  LYS B N   1 
ATOM   6951  C CA  . LYS B 1 437 ? 145.440 94.273  97.405  1.00 15.05 ? 416  LYS B CA  1 
ATOM   6952  C C   . LYS B 1 437 ? 144.885 95.643  97.785  1.00 15.05 ? 416  LYS B C   1 
ATOM   6953  O O   . LYS B 1 437 ? 145.554 96.409  98.482  1.00 15.05 ? 416  LYS B O   1 
ATOM   6954  C CB  . LYS B 1 437 ? 145.882 94.277  95.940  1.00 15.05 ? 416  LYS B CB  1 
ATOM   6955  C CG  . LYS B 1 437 ? 147.055 93.357  95.643  1.00 15.05 ? 416  LYS B CG  1 
ATOM   6956  C CD  . LYS B 1 437 ? 148.322 93.828  96.336  1.00 15.05 ? 416  LYS B CD  1 
ATOM   6957  C CE  . LYS B 1 437 ? 148.592 95.296  96.070  1.00 15.05 ? 416  LYS B CE  1 
ATOM   6958  N NZ  . LYS B 1 437 ? 149.502 95.874  97.091  1.00 15.05 ? 416  LYS B NZ  1 
ATOM   6959  N N   . ASP B 1 438 ? 143.674 95.968  97.340  1.00 15.46 ? 417  ASP B N   1 
ATOM   6960  C CA  . ASP B 1 438 ? 143.117 97.291  97.587  1.00 15.46 ? 417  ASP B CA  1 
ATOM   6961  C C   . ASP B 1 438 ? 141.598 97.210  97.614  1.00 15.46 ? 417  ASP B C   1 
ATOM   6962  O O   . ASP B 1 438 ? 141.002 96.162  97.355  1.00 15.46 ? 417  ASP B O   1 
ATOM   6963  C CB  . ASP B 1 438 ? 143.596 98.303  96.542  1.00 15.46 ? 417  ASP B CB  1 
ATOM   6964  C CG  . ASP B 1 438 ? 143.432 97.802  95.123  1.00 15.46 ? 417  ASP B CG  1 
ATOM   6965  O OD1 . ASP B 1 438 ? 142.852 96.715  94.934  1.00 15.46 ? 417  ASP B OD1 1 
ATOM   6966  O OD2 . ASP B 1 438 ? 143.895 98.494  94.193  1.00 15.46 ? 417  ASP B OD2 1 
ATOM   6967  N N   . GLN B 1 439 ? 140.982 98.358  97.911  1.00 11.05 ? 418  GLN B N   1 
ATOM   6968  C CA  . GLN B 1 439 ? 139.559 98.410  98.237  1.00 11.05 ? 418  GLN B CA  1 
ATOM   6969  C C   . GLN B 1 439 ? 138.685 97.886  97.100  1.00 11.05 ? 418  GLN B C   1 
ATOM   6970  O O   . GLN B 1 439 ? 137.645 97.260  97.345  1.00 11.05 ? 418  GLN B O   1 
ATOM   6971  C CB  . GLN B 1 439 ? 139.183 99.844  98.592  1.00 11.05 ? 418  GLN B CB  1 
ATOM   6972  C CG  . GLN B 1 439 ? 137.708 100.103 98.683  1.00 11.05 ? 418  GLN B CG  1 
ATOM   6973  C CD  . GLN B 1 439 ? 137.414 101.431 99.324  1.00 11.05 ? 418  GLN B CD  1 
ATOM   6974  O OE1 . GLN B 1 439 ? 136.262 101.751 99.612  1.00 11.05 ? 418  GLN B OE1 1 
ATOM   6975  N NE2 . GLN B 1 439 ? 138.451 102.222 99.543  1.00 11.05 ? 418  GLN B NE2 1 
ATOM   6976  N N   . ALA B 1 440 ? 139.078 98.139  95.851  1.00 12.92 ? 419  ALA B N   1 
ATOM   6977  C CA  . ALA B 1 440 ? 138.316 97.603  94.729  1.00 12.92 ? 419  ALA B CA  1 
ATOM   6978  C C   . ALA B 1 440 ? 138.317 96.081  94.749  1.00 12.92 ? 419  ALA B C   1 
ATOM   6979  O O   . ALA B 1 440 ? 137.276 95.444  94.538  1.00 12.92 ? 419  ALA B O   1 
ATOM   6980  C CB  . ALA B 1 440 ? 138.884 98.127  93.411  1.00 12.92 ? 419  ALA B CB  1 
ATOM   6981  N N   . GLU B 1 441 ? 139.476 95.481  95.021  1.00 13.83 ? 420  GLU B N   1 
ATOM   6982  C CA  . GLU B 1 441 ? 139.549 94.034  95.165  1.00 13.83 ? 420  GLU B CA  1 
ATOM   6983  C C   . GLU B 1 441 ? 138.742 93.558  96.365  1.00 13.83 ? 420  GLU B C   1 
ATOM   6984  O O   . GLU B 1 441 ? 138.171 92.462  96.334  1.00 13.83 ? 420  GLU B O   1 
ATOM   6985  C CB  . GLU B 1 441 ? 141.010 93.601  95.281  1.00 13.83 ? 420  GLU B CB  1 
ATOM   6986  C CG  . GLU B 1 441 ? 141.231 92.104  95.280  1.00 13.83 ? 420  GLU B CG  1 
ATOM   6987  C CD  . GLU B 1 441 ? 142.680 91.733  95.042  1.00 13.83 ? 420  GLU B CD  1 
ATOM   6988  O OE1 . GLU B 1 441 ? 143.461 92.619  94.642  1.00 13.83 ? 420  GLU B OE1 1 
ATOM   6989  O OE2 . GLU B 1 441 ? 143.043 90.558  95.255  1.00 13.83 ? 420  GLU B OE2 1 
ATOM   6990  N N   . ALA B 1 442 ? 138.664 94.373  97.419  1.00 10.16 ? 421  ALA B N   1 
ATOM   6991  C CA  . ALA B 1 442 ? 137.850 94.006  98.571  1.00 10.16 ? 421  ALA B CA  1 
ATOM   6992  C C   . ALA B 1 442 ? 136.376 93.920  98.203  1.00 10.16 ? 421  ALA B C   1 
ATOM   6993  O O   . ALA B 1 442 ? 135.694 92.963  98.583  1.00 10.16 ? 421  ALA B O   1 
ATOM   6994  C CB  . ALA B 1 442 ? 138.059 95.002  99.708  1.00 10.16 ? 421  ALA B CB  1 
ATOM   6995  N N   . LEU B 1 443 ? 135.862 94.907  97.461  1.00 10.03 ? 422  LEU B N   1 
ATOM   6996  C CA  . LEU B 1 443 ? 134.473 94.824  97.009  1.00 10.03 ? 422  LEU B CA  1 
ATOM   6997  C C   . LEU B 1 443 ? 134.266 93.648  96.068  1.00 10.03 ? 422  LEU B C   1 
ATOM   6998  O O   . LEU B 1 443 ? 133.249 92.946  96.150  1.00 10.03 ? 422  LEU B O   1 
ATOM   6999  C CB  . LEU B 1 443 ? 134.045 96.116  96.323  1.00 10.03 ? 422  LEU B CB  1 
ATOM   7000  C CG  . LEU B 1 443 ? 133.759 97.307  97.223  1.00 10.03 ? 422  LEU B CG  1 
ATOM   7001  C CD1 . LEU B 1 443 ? 133.309 98.486  96.382  1.00 10.03 ? 422  LEU B CD1 1 
ATOM   7002  C CD2 . LEU B 1 443 ? 132.708 96.933  98.243  1.00 10.03 ? 422  LEU B CD2 1 
ATOM   7003  N N   . GLU B 1 444 ? 135.221 93.421  95.164  1.00 14.31 ? 423  GLU B N   1 
ATOM   7004  C CA  . GLU B 1 444 ? 135.115 92.294  94.246  1.00 14.31 ? 423  GLU B CA  1 
ATOM   7005  C C   . GLU B 1 444 ? 134.952 90.984  95.001  1.00 14.31 ? 423  GLU B C   1 
ATOM   7006  O O   . GLU B 1 444 ? 134.034 90.204  94.726  1.00 14.31 ? 423  GLU B O   1 
ATOM   7007  C CB  . GLU B 1 444 ? 136.349 92.241  93.349  1.00 14.31 ? 423  GLU B CB  1 
ATOM   7008  C CG  . GLU B 1 444 ? 136.230 93.060  92.085  1.00 14.31 ? 423  GLU B CG  1 
ATOM   7009  C CD  . GLU B 1 444 ? 137.115 92.537  90.981  1.00 14.31 ? 423  GLU B CD  1 
ATOM   7010  O OE1 . GLU B 1 444 ? 137.517 91.357  91.055  1.00 14.31 ? 423  GLU B OE1 1 
ATOM   7011  O OE2 . GLU B 1 444 ? 137.411 93.303  90.042  1.00 14.31 ? 423  GLU B OE2 1 
ATOM   7012  N N   . ILE B 1 445 ? 135.833 90.728  95.967  1.00 12.65 ? 424  ILE B N   1 
ATOM   7013  C CA  . ILE B 1 445 ? 135.794 89.456  96.679  1.00 12.65 ? 424  ILE B CA  1 
ATOM   7014  C C   . ILE B 1 445 ? 134.579 89.383  97.599  1.00 12.65 ? 424  ILE B C   1 
ATOM   7015  O O   . ILE B 1 445 ? 133.954 88.325  97.733  1.00 12.65 ? 424  ILE B O   1 
ATOM   7016  C CB  . ILE B 1 445 ? 137.107 89.236  97.445  1.00 12.65 ? 424  ILE B CB  1 
ATOM   7017  C CG1 . ILE B 1 445 ? 138.275 89.161  96.467  1.00 12.65 ? 424  ILE B CG1 1 
ATOM   7018  C CG2 . ILE B 1 445 ? 137.045 87.945  98.215  1.00 12.65 ? 424  ILE B CG2 1 
ATOM   7019  C CD1 . ILE B 1 445 ? 139.610 89.421  97.104  1.00 12.65 ? 424  ILE B CD1 1 
ATOM   7020  N N   . ALA B 1 446 ? 134.219 90.496  98.246  1.00 10.01 ? 425  ALA B N   1 
ATOM   7021  C CA  . ALA B 1 446 ? 133.092 90.475  99.169  1.00 10.01 ? 425  ALA B CA  1 
ATOM   7022  C C   . ALA B 1 446 ? 131.767 90.266  98.452  1.00 10.01 ? 425  ALA B C   1 
ATOM   7023  O O   . ALA B 1 446 ? 130.812 89.773  99.059  1.00 10.01 ? 425  ALA B O   1 
ATOM   7024  C CB  . ALA B 1 446 ? 133.049 91.768  99.977  1.00 10.01 ? 425  ALA B CB  1 
ATOM   7025  N N   . ASN B 1 447 ? 131.674 90.646  97.180  1.00 10.90 ? 426  ASN B N   1 
ATOM   7026  C CA  . ASN B 1 447 ? 130.460 90.396  96.416  1.00 10.90 ? 426  ASN B CA  1 
ATOM   7027  C C   . ASN B 1 447 ? 130.529 89.123  95.584  1.00 10.90 ? 426  ASN B C   1 
ATOM   7028  O O   . ASN B 1 447 ? 129.531 88.764  94.954  1.00 10.90 ? 426  ASN B O   1 
ATOM   7029  C CB  . ASN B 1 447 ? 130.156 91.583  95.498  1.00 10.90 ? 426  ASN B CB  1 
ATOM   7030  C CG  . ASN B 1 447 ? 129.656 92.793  96.257  1.00 10.90 ? 426  ASN B CG  1 
ATOM   7031  O OD1 . ASN B 1 447 ? 129.164 92.680  97.377  1.00 10.90 ? 426  ASN B OD1 1 
ATOM   7032  N ND2 . ASN B 1 447 ? 129.775 93.959  95.643  1.00 10.90 ? 426  ASN B ND2 1 
ATOM   7033  N N   . ASP B 1 448 ? 131.673 88.434  95.577  1.00 19.19 ? 427  ASP B N   1 
ATOM   7034  C CA  . ASP B 1 448 ? 131.899 87.282  94.711  1.00 19.19 ? 427  ASP B CA  1 
ATOM   7035  C C   . ASP B 1 448 ? 131.038 86.082  95.074  1.00 19.19 ? 427  ASP B C   1 
ATOM   7036  O O   . ASP B 1 448 ? 130.915 85.163  94.259  1.00 19.19 ? 427  ASP B O   1 
ATOM   7037  C CB  . ASP B 1 448 ? 133.377 86.888  94.760  1.00 19.19 ? 427  ASP B CB  1 
ATOM   7038  C CG  . ASP B 1 448 ? 133.754 85.860  93.704  1.00 19.19 ? 427  ASP B CG  1 
ATOM   7039  O OD1 . ASP B 1 448 ? 133.073 85.784  92.661  1.00 19.19 ? 427  ASP B OD1 1 
ATOM   7040  O OD2 . ASP B 1 448 ? 134.746 85.132  93.917  1.00 19.19 ? 427  ASP B OD2 1 
ATOM   7041  N N   . THR B 1 449 ? 130.434 86.066  96.256  1.00 20.98 ? 428  THR B N   1 
ATOM   7042  C CA  . THR B 1 449 ? 129.627 84.929  96.664  1.00 20.98 ? 428  THR B CA  1 
ATOM   7043  C C   . THR B 1 449 ? 128.231 85.017  96.052  1.00 20.98 ? 428  THR B C   1 
ATOM   7044  O O   . THR B 1 449 ? 127.915 85.924  95.278  1.00 20.98 ? 428  THR B O   1 
ATOM   7045  C CB  . THR B 1 449 ? 129.556 84.849  98.185  1.00 20.98 ? 428  THR B CB  1 
ATOM   7046  O OG1 . THR B 1 449 ? 128.967 83.600  98.571  1.00 20.98 ? 428  THR B OG1 1 
ATOM   7047  C CG2 . THR B 1 449 ? 128.732 86.004  98.740  1.00 20.98 ? 428  THR B CG2 1 
ATOM   7048  N N   . LEU B 1 450 ? 127.381 84.049  96.397  1.00 21.85 ? 429  LEU B N   1 
ATOM   7049  C CA  . LEU B 1 450 ? 126.003 84.019  95.929  1.00 21.85 ? 429  LEU B CA  1 
ATOM   7050  C C   . LEU B 1 450 ? 124.996 84.439  96.991  1.00 21.85 ? 429  LEU B C   1 
ATOM   7051  O O   . LEU B 1 450 ? 123.808 84.557  96.680  1.00 21.85 ? 429  LEU B O   1 
ATOM   7052  C CB  . LEU B 1 450 ? 125.635 82.615  95.424  1.00 21.85 ? 429  LEU B CB  1 
ATOM   7053  C CG  . LEU B 1 450 ? 126.304 82.086  94.155  1.00 21.85 ? 429  LEU B CG  1 
ATOM   7054  C CD1 . LEU B 1 450 ? 127.655 81.457  94.469  1.00 21.85 ? 429  LEU B CD1 1 
ATOM   7055  C CD2 . LEU B 1 450 ? 125.398 81.092  93.443  1.00 21.85 ? 429  LEU B CD2 1 
ATOM   7056  N N   . TYR B 1 451 ? 125.430 84.660  98.225  1.00 21.81 ? 430  TYR B N   1 
ATOM   7057  C CA  . TYR B 1 451 ? 124.543 85.059  99.305  1.00 21.81 ? 430  TYR B CA  1 
ATOM   7058  C C   . TYR B 1 451 ? 124.778 86.523  99.653  1.00 21.81 ? 430  TYR B C   1 
ATOM   7059  O O   . TYR B 1 451 ? 125.882 87.048  99.500  1.00 21.81 ? 430  TYR B O   1 
ATOM   7060  C CB  . TYR B 1 451 ? 124.758 84.186  100.544 1.00 21.81 ? 430  TYR B CB  1 
ATOM   7061  C CG  . TYR B 1 451 ? 124.568 82.699  100.308 1.00 21.81 ? 430  TYR B CG  1 
ATOM   7062  C CD1 . TYR B 1 451 ? 123.816 82.230  99.238  1.00 21.81 ? 430  TYR B CD1 1 
ATOM   7063  C CD2 . TYR B 1 451 ? 125.141 81.767  101.159 1.00 21.81 ? 430  TYR B CD2 1 
ATOM   7064  C CE1 . TYR B 1 451 ? 123.642 80.878  99.025  1.00 21.81 ? 430  TYR B CE1 1 
ATOM   7065  C CE2 . TYR B 1 451 ? 124.970 80.414  100.955 1.00 21.81 ? 430  TYR B CE2 1 
ATOM   7066  C CZ  . TYR B 1 451 ? 124.219 79.975  99.887  1.00 21.81 ? 430  TYR B CZ  1 
ATOM   7067  O OH  . TYR B 1 451 ? 124.046 78.628  99.678  1.00 21.81 ? 430  TYR B OH  1 
ATOM   7068  N N   . GLY B 1 452 ? 123.728 87.182  100.122 1.00 13.98 ? 431  GLY B N   1 
ATOM   7069  C CA  . GLY B 1 452 ? 123.803 88.606  100.357 1.00 13.98 ? 431  GLY B CA  1 
ATOM   7070  C C   . GLY B 1 452 ? 123.322 89.034  101.724 1.00 13.98 ? 431  GLY B C   1 
ATOM   7071  O O   . GLY B 1 452 ? 122.663 90.068  101.852 1.00 13.98 ? 431  GLY B O   1 
ATOM   7072  N N   . LEU B 1 453 ? 123.628 88.252  102.756 1.00 13.81 ? 432  LEU B N   1 
ATOM   7073  C CA  . LEU B 1 453 ? 123.045 88.532  104.062 1.00 13.81 ? 432  LEU B CA  1 
ATOM   7074  C C   . LEU B 1 453 ? 123.780 89.648  104.795 1.00 13.81 ? 432  LEU B C   1 
ATOM   7075  O O   . LEU B 1 453 ? 123.167 90.646  105.183 1.00 13.81 ? 432  LEU B O   1 
ATOM   7076  C CB  . LEU B 1 453 ? 123.025 87.269  104.914 1.00 13.81 ? 432  LEU B CB  1 
ATOM   7077  C CG  . LEU B 1 453 ? 122.111 87.388  106.131 1.00 13.81 ? 432  LEU B CG  1 
ATOM   7078  C CD1 . LEU B 1 453 ? 120.777 88.017  105.769 1.00 13.81 ? 432  LEU B CD1 1 
ATOM   7079  C CD2 . LEU B 1 453 ? 121.906 86.038  106.751 1.00 13.81 ? 432  LEU B CD2 1 
ATOM   7080  N N   . GLY B 1 454 ? 125.087 89.497  105.005 1.00 7.75  ? 433  GLY B N   1 
ATOM   7081  C CA  . GLY B 1 454 ? 125.813 90.430  105.840 1.00 7.75  ? 433  GLY B CA  1 
ATOM   7082  C C   . GLY B 1 454 ? 127.264 90.567  105.432 1.00 7.75  ? 433  GLY B C   1 
ATOM   7083  O O   . GLY B 1 454 ? 127.744 89.890  104.522 1.00 7.75  ? 433  GLY B O   1 
ATOM   7084  N N   . ALA B 1 455 ? 127.958 91.470  106.122 1.00 4.50  ? 434  ALA B N   1 
ATOM   7085  C CA  . ALA B 1 455 ? 129.380 91.713  105.924 1.00 4.50  ? 434  ALA B CA  1 
ATOM   7086  C C   . ALA B 1 455 ? 129.871 92.638  107.027 1.00 4.50  ? 434  ALA B C   1 
ATOM   7087  O O   . ALA B 1 455 ? 129.091 93.372  107.638 1.00 4.50  ? 434  ALA B O   1 
ATOM   7088  C CB  . ALA B 1 455 ? 129.671 92.319  104.551 1.00 4.50  ? 434  ALA B CB  1 
ATOM   7089  N N   . GLY B 1 456 ? 131.165 92.582  107.279 1.00 4.18  ? 435  GLY B N   1 
ATOM   7090  C CA  . GLY B 1 456 ? 131.794 93.463  108.251 1.00 4.18  ? 435  GLY B CA  1 
ATOM   7091  C C   . GLY B 1 456 ? 132.971 94.192  107.643 1.00 4.18  ? 435  GLY B C   1 
ATOM   7092  O O   . GLY B 1 456 ? 133.716 93.629  106.848 1.00 4.18  ? 435  GLY B O   1 
ATOM   7093  N N   . VAL B 1 457 ? 133.137 95.454  108.034 1.00 4.17  ? 436  VAL B N   1 
ATOM   7094  C CA  . VAL B 1 457 ? 134.192 96.311  107.501 1.00 4.17  ? 436  VAL B CA  1 
ATOM   7095  C C   . VAL B 1 457 ? 134.987 96.888  108.663 1.00 4.17  ? 436  VAL B C   1 
ATOM   7096  O O   . VAL B 1 457 ? 134.404 97.359  109.645 1.00 4.17  ? 436  VAL B O   1 
ATOM   7097  C CB  . VAL B 1 457 ? 133.622 97.439  106.621 1.00 4.17  ? 436  VAL B CB  1 
ATOM   7098  C CG1 . VAL B 1 457 ? 134.644 98.537  106.436 1.00 4.17  ? 436  VAL B CG1 1 
ATOM   7099  C CG2 . VAL B 1 457 ? 133.198 96.894  105.279 1.00 4.17  ? 436  VAL B CG2 1 
ATOM   7100  N N   . TRP B 1 458 ? 136.315 96.848  108.556 1.00 5.46  ? 437  TRP B N   1 
ATOM   7101  C CA  . TRP B 1 458 ? 137.203 97.337  109.606 1.00 5.46  ? 437  TRP B CA  1 
ATOM   7102  C C   . TRP B 1 458 ? 138.190 98.324  109.002 1.00 5.46  ? 437  TRP B C   1 
ATOM   7103  O O   . TRP B 1 458 ? 139.112 97.927  108.283 1.00 5.46  ? 437  TRP B O   1 
ATOM   7104  C CB  . TRP B 1 458 ? 137.931 96.182  110.293 1.00 5.46  ? 437  TRP B CB  1 
ATOM   7105  C CG  . TRP B 1 458 ? 136.993 95.246  110.968 1.00 5.46  ? 437  TRP B CG  1 
ATOM   7106  C CD1 . TRP B 1 458 ? 136.338 94.200  110.399 1.00 5.46  ? 437  TRP B CD1 1 
ATOM   7107  C CD2 . TRP B 1 458 ? 136.571 95.289  112.331 1.00 5.46  ? 437  TRP B CD2 1 
ATOM   7108  N NE1 . TRP B 1 458 ? 135.545 93.578  111.324 1.00 5.46  ? 437  TRP B NE1 1 
ATOM   7109  C CE2 . TRP B 1 458 ? 135.668 94.230  112.520 1.00 5.46  ? 437  TRP B CE2 1 
ATOM   7110  C CE3 . TRP B 1 458 ? 136.870 96.118  113.412 1.00 5.46  ? 437  TRP B CE3 1 
ATOM   7111  C CZ2 . TRP B 1 458 ? 135.066 93.976  113.740 1.00 5.46  ? 437  TRP B CZ2 1 
ATOM   7112  C CZ3 . TRP B 1 458 ? 136.270 95.865  114.620 1.00 5.46  ? 437  TRP B CZ3 1 
ATOM   7113  C CH2 . TRP B 1 458 ? 135.381 94.801  114.778 1.00 5.46  ? 437  TRP B CH2 1 
ATOM   7114  N N   . SER B 1 459 ? 137.994 99.606  109.296 1.00 6.68  ? 438  SER B N   1 
ATOM   7115  C CA  . SER B 1 459 ? 138.902 100.654 108.857 1.00 6.68  ? 438  SER B CA  1 
ATOM   7116  C C   . SER B 1 459 ? 138.679 101.878 109.729 1.00 6.68  ? 438  SER B C   1 
ATOM   7117  O O   . SER B 1 459 ? 137.664 101.989 110.419 1.00 6.68  ? 438  SER B O   1 
ATOM   7118  C CB  . SER B 1 459 ? 138.694 100.996 107.381 1.00 6.68  ? 438  SER B CB  1 
ATOM   7119  O OG  . SER B 1 459 ? 139.579 102.017 106.971 1.00 6.68  ? 438  SER B OG  1 
ATOM   7120  N N   . ARG B 1 460 ? 139.650 102.791 109.701 1.00 9.68  ? 439  ARG B N   1 
ATOM   7121  C CA  . ARG B 1 460 ? 139.498 104.089 110.346 1.00 9.68  ? 439  ARG B CA  1 
ATOM   7122  C C   . ARG B 1 460 ? 139.206 105.216 109.367 1.00 9.68  ? 439  ARG B C   1 
ATOM   7123  O O   . ARG B 1 460 ? 138.742 106.276 109.792 1.00 9.68  ? 439  ARG B O   1 
ATOM   7124  C CB  . ARG B 1 460 ? 140.753 104.451 111.147 1.00 9.68  ? 439  ARG B CB  1 
ATOM   7125  C CG  . ARG B 1 460 ? 141.339 103.323 111.972 1.00 9.68  ? 439  ARG B CG  1 
ATOM   7126  C CD  . ARG B 1 460 ? 142.550 103.807 112.752 1.00 9.68  ? 439  ARG B CD  1 
ATOM   7127  N NE  . ARG B 1 460 ? 143.365 102.713 113.272 1.00 9.68  ? 439  ARG B NE  1 
ATOM   7128  C CZ  . ARG B 1 460 ? 143.791 102.634 114.527 1.00 9.68  ? 439  ARG B CZ  1 
ATOM   7129  N NH1 . ARG B 1 460 ? 143.481 103.585 115.391 1.00 9.68  ? 439  ARG B NH1 1 
ATOM   7130  N NH2 . ARG B 1 460 ? 144.528 101.607 114.919 1.00 9.68  ? 439  ARG B NH2 1 
ATOM   7131  N N   . ASP B 1 461 ? 139.465 105.017 108.078 1.00 7.42  ? 440  ASP B N   1 
ATOM   7132  C CA  . ASP B 1 461 ? 139.195 106.037 107.077 1.00 7.42  ? 440  ASP B CA  1 
ATOM   7133  C C   . ASP B 1 461 ? 137.703 106.093 106.781 1.00 7.42  ? 440  ASP B C   1 
ATOM   7134  O O   . ASP B 1 461 ? 137.069 105.059 106.560 1.00 7.42  ? 440  ASP B O   1 
ATOM   7135  C CB  . ASP B 1 461 ? 139.977 105.743 105.801 1.00 7.42  ? 440  ASP B CB  1 
ATOM   7136  C CG  . ASP B 1 461 ? 139.746 106.779 104.723 1.00 7.42  ? 440  ASP B CG  1 
ATOM   7137  O OD1 . ASP B 1 461 ? 139.338 107.910 105.058 1.00 7.42  ? 440  ASP B OD1 1 
ATOM   7138  O OD2 . ASP B 1 461 ? 139.981 106.465 103.537 1.00 7.42  ? 440  ASP B OD2 1 
ATOM   7139  N N   . ALA B 1 462 ? 137.147 107.306 106.767 1.00 4.97  ? 441  ALA B N   1 
ATOM   7140  C CA  . ALA B 1 462 ? 135.711 107.468 106.559 1.00 4.97  ? 441  ALA B CA  1 
ATOM   7141  C C   . ALA B 1 462 ? 135.304 107.100 105.136 1.00 4.97  ? 441  ALA B C   1 
ATOM   7142  O O   . ALA B 1 462 ? 134.299 106.411 104.929 1.00 4.97  ? 441  ALA B O   1 
ATOM   7143  C CB  . ALA B 1 462 ? 135.297 108.900 106.884 1.00 4.97  ? 441  ALA B CB  1 
ATOM   7144  N N   . ASN B 1 463 ? 136.065 107.562 104.141 1.00 4.73  ? 442  ASN B N   1 
ATOM   7145  C CA  . ASN B 1 463 ? 135.695 107.300 102.754 1.00 4.73  ? 442  ASN B CA  1 
ATOM   7146  C C   . ASN B 1 463 ? 135.742 105.814 102.440 1.00 4.73  ? 442  ASN B C   1 
ATOM   7147  O O   . ASN B 1 463 ? 134.846 105.286 101.772 1.00 4.73  ? 442  ASN B O   1 
ATOM   7148  C CB  . ASN B 1 463 ? 136.607 108.068 101.801 1.00 4.73  ? 442  ASN B CB  1 
ATOM   7149  C CG  . ASN B 1 463 ? 136.571 109.557 102.034 1.00 4.73  ? 442  ASN B CG  1 
ATOM   7150  O OD1 . ASN B 1 463 ? 135.519 110.182 101.952 1.00 4.73  ? 442  ASN B OD1 1 
ATOM   7151  N ND2 . ASN B 1 463 ? 137.727 110.139 102.316 1.00 4.73  ? 442  ASN B ND2 1 
ATOM   7152  N N   . THR B 1 464 ? 136.783 105.123 102.906 1.00 4.96  ? 443  THR B N   1 
ATOM   7153  C CA  . THR B 1 464 ? 136.848 103.678 102.718 1.00 4.96  ? 443  THR B CA  1 
ATOM   7154  C C   . THR B 1 464 ? 135.671 102.987 103.381 1.00 4.96  ? 443  THR B C   1 
ATOM   7155  O O   . THR B 1 464 ? 135.040 102.111 102.781 1.00 4.96  ? 443  THR B O   1 
ATOM   7156  C CB  . THR B 1 464 ? 138.161 103.131 103.268 1.00 4.96  ? 443  THR B CB  1 
ATOM   7157  O OG1 . THR B 1 464 ? 139.256 103.668 102.517 1.00 4.96  ? 443  THR B OG1 1 
ATOM   7158  C CG2 . THR B 1 464 ? 138.178 101.624 103.189 1.00 4.96  ? 443  THR B CG2 1 
ATOM   7159  N N   . CYS B 1 465 ? 135.343 103.385 104.610 1.00 3.61  ? 444  CYS B N   1 
ATOM   7160  C CA  . CYS B 1 465 ? 134.241 102.746 105.315 1.00 3.61  ? 444  CYS B CA  1 
ATOM   7161  C C   . CYS B 1 465 ? 132.932 102.924 104.564 1.00 3.61  ? 444  CYS B C   1 
ATOM   7162  O O   . CYS B 1 465 ? 132.167 101.970 104.409 1.00 3.61  ? 444  CYS B O   1 
ATOM   7163  C CB  . CYS B 1 465 ? 134.127 103.302 106.732 1.00 3.61  ? 444  CYS B CB  1 
ATOM   7164  S SG  . CYS B 1 465 ? 135.330 102.632 107.885 1.00 3.61  ? 444  CYS B SG  1 
ATOM   7165  N N   . TYR B 1 466 ? 132.671 104.132 104.061 1.00 2.56  ? 445  TYR B N   1 
ATOM   7166  C CA  . TYR B 1 466 ? 131.413 104.389 103.367 1.00 2.56  ? 445  TYR B CA  1 
ATOM   7167  C C   . TYR B 1 466 ? 131.350 103.667 102.029 1.00 2.56  ? 445  TYR B C   1 
ATOM   7168  O O   . TYR B 1 466 ? 130.335 103.047 101.699 1.00 2.56  ? 445  TYR B O   1 
ATOM   7169  C CB  . TYR B 1 466 ? 131.221 105.889 103.172 1.00 2.56  ? 445  TYR B CB  1 
ATOM   7170  C CG  . TYR B 1 466 ? 129.952 106.263 102.447 1.00 2.56  ? 445  TYR B CG  1 
ATOM   7171  C CD1 . TYR B 1 466 ? 128.734 106.281 103.103 1.00 2.56  ? 445  TYR B CD1 1 
ATOM   7172  C CD2 . TYR B 1 466 ? 129.978 106.617 101.105 1.00 2.56  ? 445  TYR B CD2 1 
ATOM   7173  C CE1 . TYR B 1 466 ? 127.579 106.631 102.443 1.00 2.56  ? 445  TYR B CE1 1 
ATOM   7174  C CE2 . TYR B 1 466 ? 128.832 106.967 100.439 1.00 2.56  ? 445  TYR B CE2 1 
ATOM   7175  C CZ  . TYR B 1 466 ? 127.636 106.974 101.112 1.00 2.56  ? 445  TYR B CZ  1 
ATOM   7176  O OH  . TYR B 1 466 ? 126.491 107.322 100.446 1.00 2.56  ? 445  TYR B OH  1 
ATOM   7177  N N   . ARG B 1 467 ? 132.412 103.754 101.228 1.00 3.10  ? 446  ARG B N   1 
ATOM   7178  C CA  . ARG B 1 467 ? 132.384 103.099 99.926  1.00 3.10  ? 446  ARG B CA  1 
ATOM   7179  C C   . ARG B 1 467 ? 132.311 101.586 100.061 1.00 3.10  ? 446  ARG B C   1 
ATOM   7180  O O   . ARG B 1 467 ? 131.715 100.920 99.210  1.00 3.10  ? 446  ARG B O   1 
ATOM   7181  C CB  . ARG B 1 467 ? 133.605 103.493 99.101  1.00 3.10  ? 446  ARG B CB  1 
ATOM   7182  C CG  . ARG B 1 467 ? 133.731 104.972 98.858  1.00 3.10  ? 446  ARG B CG  1 
ATOM   7183  C CD  . ARG B 1 467 ? 132.503 105.514 98.172  1.00 3.10  ? 446  ARG B CD  1 
ATOM   7184  N NE  . ARG B 1 467 ? 132.682 106.901 97.764  1.00 3.10  ? 446  ARG B NE  1 
ATOM   7185  C CZ  . ARG B 1 467 ? 131.783 107.596 97.082  1.00 3.10  ? 446  ARG B CZ  1 
ATOM   7186  N NH1 . ARG B 1 467 ? 130.640 107.033 96.727  1.00 3.10  ? 446  ARG B NH1 1 
ATOM   7187  N NH2 . ARG B 1 467 ? 132.029 108.851 96.751  1.00 3.10  ? 446  ARG B NH2 1 
ATOM   7188  N N   . MET B 1 468 ? 132.895 101.026 101.121 1.00 4.64  ? 447  MET B N   1 
ATOM   7189  C CA  . MET B 1 468 ? 132.791 99.594  101.346 1.00 4.64  ? 447  MET B CA  1 
ATOM   7190  C C   . MET B 1 468 ? 131.421 99.207  101.875 1.00 4.64  ? 447  MET B C   1 
ATOM   7191  O O   . MET B 1 468 ? 130.870 98.180  101.472 1.00 4.64  ? 447  MET B O   1 
ATOM   7192  C CB  . MET B 1 468 ? 133.882 99.148  102.305 1.00 4.64  ? 447  MET B CB  1 
ATOM   7193  C CG  . MET B 1 468 ? 135.245 99.181  101.678 1.00 4.64  ? 447  MET B CG  1 
ATOM   7194  S SD  . MET B 1 468 ? 135.410 98.040  100.302 1.00 4.64  ? 447  MET B SD  1 
ATOM   7195  C CE  . MET B 1 468 ? 134.971 96.498  101.090 1.00 4.64  ? 447  MET B CE  1 
ATOM   7196  N N   . GLY B 1 469 ? 130.848 100.009 102.770 1.00 3.08  ? 448  GLY B N   1 
ATOM   7197  C CA  . GLY B 1 469 ? 129.499 99.740  103.211 1.00 3.08  ? 448  GLY B CA  1 
ATOM   7198  C C   . GLY B 1 469 ? 128.480 99.807  102.100 1.00 3.08  ? 448  GLY B C   1 
ATOM   7199  O O   . GLY B 1 469 ? 127.558 98.989  102.069 1.00 3.08  ? 448  GLY B O   1 
ATOM   7200  N N   . ARG B 1 470 ? 128.636 100.749 101.175 1.00 2.64  ? 449  ARG B N   1 
ATOM   7201  C CA  . ARG B 1 470 ? 127.663 100.940 100.113 1.00 2.64  ? 449  ARG B CA  1 
ATOM   7202  C C   . ARG B 1 470 ? 127.943 100.100 98.878  1.00 2.64  ? 449  ARG B C   1 
ATOM   7203  O O   . ARG B 1 470 ? 127.030 99.893  98.074  1.00 2.64  ? 449  ARG B O   1 
ATOM   7204  C CB  . ARG B 1 470 ? 127.603 102.419 99.717  1.00 2.64  ? 449  ARG B CB  1 
ATOM   7205  C CG  . ARG B 1 470 ? 127.029 103.320 100.790 1.00 2.64  ? 449  ARG B CG  1 
ATOM   7206  C CD  . ARG B 1 470 ? 125.556 103.575 100.558 1.00 2.64  ? 449  ARG B CD  1 
ATOM   7207  N NE  . ARG B 1 470 ? 125.245 103.600 99.134  1.00 2.64  ? 449  ARG B NE  1 
ATOM   7208  C CZ  . ARG B 1 470 ? 124.017 103.660 98.635  1.00 2.64  ? 449  ARG B CZ  1 
ATOM   7209  N NH1 . ARG B 1 470 ? 122.975 103.702 99.442  1.00 2.64  ? 449  ARG B NH1 1 
ATOM   7210  N NH2 . ARG B 1 470 ? 123.834 103.674 97.325  1.00 2.64  ? 449  ARG B NH2 1 
ATOM   7211  N N   . GLY B 1 471 ? 129.167 99.613  98.705  1.00 3.90  ? 450  GLY B N   1 
ATOM   7212  C CA  . GLY B 1 471 ? 129.487 98.786  97.561  1.00 3.90  ? 450  GLY B CA  1 
ATOM   7213  C C   . GLY B 1 471 ? 129.280 97.309  97.806  1.00 3.90  ? 450  GLY B C   1 
ATOM   7214  O O   . GLY B 1 471 ? 129.183 96.524  96.860  1.00 3.90  ? 450  GLY B O   1 
ATOM   7215  N N   . ILE B 1 472 ? 129.208 96.916  99.074  1.00 4.42  ? 451  ILE B N   1 
ATOM   7216  C CA  . ILE B 1 472 ? 129.005 95.516  99.423  1.00 4.42  ? 451  ILE B CA  1 
ATOM   7217  C C   . ILE B 1 472 ? 127.546 95.155  99.180  1.00 4.42  ? 451  ILE B C   1 
ATOM   7218  O O   . ILE B 1 472 ? 126.640 95.723  99.800  1.00 4.42  ? 451  ILE B O   1 
ATOM   7219  C CB  . ILE B 1 472 ? 129.412 95.254  100.877 1.00 4.42  ? 451  ILE B CB  1 
ATOM   7220  C CG1 . ILE B 1 472 ? 130.922 95.064  100.975 1.00 4.42  ? 451  ILE B CG1 1 
ATOM   7221  C CG2 . ILE B 1 472 ? 128.712 94.030  101.418 1.00 4.42  ? 451  ILE B CG2 1 
ATOM   7222  C CD1 . ILE B 1 472 ? 131.447 95.150  102.381 1.00 4.42  ? 451  ILE B CD1 1 
ATOM   7223  N N   . LYS B 1 473 ? 127.312 94.209  98.269  1.00 6.31  ? 452  LYS B N   1 
ATOM   7224  C CA  . LYS B 1 473 ? 125.958 93.770  97.931  1.00 6.31  ? 452  LYS B CA  1 
ATOM   7225  C C   . LYS B 1 473 ? 125.460 92.837  99.030  1.00 6.31  ? 452  LYS B C   1 
ATOM   7226  O O   . LYS B 1 473 ? 125.388 91.616  98.879  1.00 6.31  ? 452  LYS B O   1 
ATOM   7227  C CB  . LYS B 1 473 ? 125.932 93.093  96.568  1.00 6.31  ? 452  LYS B CB  1 
ATOM   7228  C CG  . LYS B 1 473 ? 126.363 93.981  95.421  1.00 6.31  ? 452  LYS B CG  1 
ATOM   7229  C CD  . LYS B 1 473 ? 125.438 95.168  95.272  1.00 6.31  ? 452  LYS B CD  1 
ATOM   7230  C CE  . LYS B 1 473 ? 126.085 96.280  94.464  1.00 6.31  ? 452  LYS B CE  1 
ATOM   7231  N NZ  . LYS B 1 473 ? 126.883 97.210  95.306  1.00 6.31  ? 452  LYS B NZ  1 
ATOM   7232  N N   . ALA B 1 474 ? 125.118 93.432  100.166 1.00 6.04  ? 453  ALA B N   1 
ATOM   7233  C CA  . ALA B 1 474 ? 124.564 92.682  101.278 1.00 6.04  ? 453  ALA B CA  1 
ATOM   7234  C C   . ALA B 1 474 ? 123.555 93.559  101.992 1.00 6.04  ? 453  ALA B C   1 
ATOM   7235  O O   . ALA B 1 474 ? 123.664 94.785  101.982 1.00 6.04  ? 453  ALA B O   1 
ATOM   7236  C CB  . ALA B 1 474 ? 125.648 92.216  102.253 1.00 6.04  ? 453  ALA B CB  1 
ATOM   7237  N N   . GLY B 1 475 ? 122.569 92.916  102.614 1.00 6.25  ? 454  GLY B N   1 
ATOM   7238  C CA  . GLY B 1 475 ? 121.501 93.658  103.254 1.00 6.25  ? 454  GLY B CA  1 
ATOM   7239  C C   . GLY B 1 475 ? 121.924 94.377  104.508 1.00 6.25  ? 454  GLY B C   1 
ATOM   7240  O O   . GLY B 1 475 ? 121.269 95.342  104.907 1.00 6.25  ? 454  GLY B O   1 
ATOM   7241  N N   . ARG B 1 476 ? 123.000 93.928  105.140 1.00 6.09  ? 455  ARG B N   1 
ATOM   7242  C CA  . ARG B 1 476 ? 123.485 94.525  106.370 1.00 6.09  ? 455  ARG B CA  1 
ATOM   7243  C C   . ARG B 1 476 ? 125.002 94.546  106.345 1.00 6.09  ? 455  ARG B C   1 
ATOM   7244  O O   . ARG B 1 476 ? 125.633 93.557  105.970 1.00 6.09  ? 455  ARG B O   1 
ATOM   7245  C CB  . ARG B 1 476 ? 122.991 93.753  107.590 1.00 6.09  ? 455  ARG B CB  1 
ATOM   7246  C CG  . ARG B 1 476 ? 123.472 94.311  108.897 1.00 6.09  ? 455  ARG B CG  1 
ATOM   7247  C CD  . ARG B 1 476 ? 122.927 93.485  110.029 1.00 6.09  ? 455  ARG B CD  1 
ATOM   7248  N NE  . ARG B 1 476 ? 121.589 93.890  110.442 1.00 6.09  ? 455  ARG B NE  1 
ATOM   7249  C CZ  . ARG B 1 476 ? 121.351 94.769  111.404 1.00 6.09  ? 455  ARG B CZ  1 
ATOM   7250  N NH1 . ARG B 1 476 ? 122.363 95.332  112.040 1.00 6.09  ? 455  ARG B NH1 1 
ATOM   7251  N NH2 . ARG B 1 476 ? 120.108 95.085  111.731 1.00 6.09  ? 455  ARG B NH2 1 
ATOM   7252  N N   . VAL B 1 477 ? 125.583 95.676  106.732 1.00 2.77  ? 456  VAL B N   1 
ATOM   7253  C CA  . VAL B 1 477 ? 127.029 95.834  106.769 1.00 2.77  ? 456  VAL B CA  1 
ATOM   7254  C C   . VAL B 1 477 ? 127.423 96.352  108.140 1.00 2.77  ? 456  VAL B C   1 
ATOM   7255  O O   . VAL B 1 477 ? 126.874 97.351  108.615 1.00 2.77  ? 456  VAL B O   1 
ATOM   7256  C CB  . VAL B 1 477 ? 127.537 96.773  105.662 1.00 2.77  ? 456  VAL B CB  1 
ATOM   7257  C CG1 . VAL B 1 477 ? 129.001 97.067  105.860 1.00 2.77  ? 456  VAL B CG1 1 
ATOM   7258  C CG2 . VAL B 1 477 ? 127.323 96.140  104.311 1.00 2.77  ? 456  VAL B CG2 1 
ATOM   7259  N N   . TRP B 1 478 ? 128.360 95.667  108.777 1.00 4.18  ? 457  TRP B N   1 
ATOM   7260  C CA  . TRP B 1 478 ? 128.900 96.065  110.065 1.00 4.18  ? 457  TRP B CA  1 
ATOM   7261  C C   . TRP B 1 478 ? 130.223 96.778  109.850 1.00 4.18  ? 457  TRP B C   1 
ATOM   7262  O O   . TRP B 1 478 ? 131.103 96.262  109.159 1.00 4.18  ? 457  TRP B O   1 
ATOM   7263  C CB  . TRP B 1 478 ? 129.101 94.849  110.963 1.00 4.18  ? 457  TRP B CB  1 
ATOM   7264  C CG  . TRP B 1 478 ? 127.870 94.358  111.637 1.00 4.18  ? 457  TRP B CG  1 
ATOM   7265  C CD1 . TRP B 1 478 ? 127.259 94.908  112.716 1.00 4.18  ? 457  TRP B CD1 1 
ATOM   7266  C CD2 . TRP B 1 478 ? 127.100 93.210  111.281 1.00 4.18  ? 457  TRP B CD2 1 
ATOM   7267  N NE1 . TRP B 1 478 ? 126.158 94.172  113.063 1.00 4.18  ? 457  TRP B NE1 1 
ATOM   7268  C CE2 . TRP B 1 478 ? 126.037 93.124  112.193 1.00 4.18  ? 457  TRP B CE2 1 
ATOM   7269  C CE3 . TRP B 1 478 ? 127.203 92.250  110.275 1.00 4.18  ? 457  TRP B CE3 1 
ATOM   7270  C CZ2 . TRP B 1 478 ? 125.091 92.112  112.137 1.00 4.18  ? 457  TRP B CZ2 1 
ATOM   7271  C CZ3 . TRP B 1 478 ? 126.264 91.248  110.221 1.00 4.18  ? 457  TRP B CZ3 1 
ATOM   7272  C CH2 . TRP B 1 478 ? 125.220 91.186  111.144 1.00 4.18  ? 457  TRP B CH2 1 
ATOM   7273  N N   . THR B 1 479 ? 130.359 97.963  110.429 1.00 3.75  ? 458  THR B N   1 
ATOM   7274  C CA  . THR B 1 479 ? 131.570 98.762  110.289 1.00 3.75  ? 458  THR B CA  1 
ATOM   7275  C C   . THR B 1 479 ? 132.201 98.913  111.663 1.00 3.75  ? 458  THR B C   1 
ATOM   7276  O O   . THR B 1 479 ? 131.609 99.529  112.555 1.00 3.75  ? 458  THR B O   1 
ATOM   7277  C CB  . THR B 1 479 ? 131.261 100.123 109.672 1.00 3.75  ? 458  THR B CB  1 
ATOM   7278  O OG1 . THR B 1 479 ? 130.674 99.940  108.378 1.00 3.75  ? 458  THR B OG1 1 
ATOM   7279  C CG2 . THR B 1 479 ? 132.528 100.929 109.522 1.00 3.75  ? 458  THR B CG2 1 
ATOM   7280  N N   . ASN B 1 480 ? 133.396 98.348  111.830 1.00 4.65  ? 459  ASN B N   1 
ATOM   7281  C CA  . ASN B 1 480 ? 134.158 98.433  113.076 1.00 4.65  ? 459  ASN B CA  1 
ATOM   7282  C C   . ASN B 1 480 ? 133.381 97.859  114.259 1.00 4.65  ? 459  ASN B C   1 
ATOM   7283  O O   . ASN B 1 480 ? 133.565 98.275  115.403 1.00 4.65  ? 459  ASN B O   1 
ATOM   7284  C CB  . ASN B 1 480 ? 134.598 99.873  113.351 1.00 4.65  ? 459  ASN B CB  1 
ATOM   7285  C CG  . ASN B 1 480 ? 135.427 100.450 112.220 1.00 4.65  ? 459  ASN B CG  1 
ATOM   7286  O OD1 . ASN B 1 480 ? 136.134 99.726  111.523 1.00 4.65  ? 459  ASN B OD1 1 
ATOM   7287  N ND2 . ASN B 1 480 ? 135.336 101.756 112.026 1.00 4.65  ? 459  ASN B ND2 1 
ATOM   7288  N N   . CYS B 1 481 ? 132.516 96.894  113.975 1.00 5.48  ? 460  CYS B N   1 
ATOM   7289  C CA  . CYS B 1 481 ? 131.811 96.096  114.968 1.00 5.48  ? 460  CYS B CA  1 
ATOM   7290  C C   . CYS B 1 481 ? 131.317 94.857  114.242 1.00 5.48  ? 460  CYS B C   1 
ATOM   7291  O O   . CYS B 1 481 ? 131.514 94.723  113.033 1.00 5.48  ? 460  CYS B O   1 
ATOM   7292  C CB  . CYS B 1 481 ? 130.659 96.870  115.603 1.00 5.48  ? 460  CYS B CB  1 
ATOM   7293  S SG  . CYS B 1 481 ? 129.256 97.127  114.507 1.00 5.48  ? 460  CYS B SG  1 
ATOM   7294  N N   . TYR B 1 482 ? 130.679 93.944  114.973 1.00 8.34  ? 461  TYR B N   1 
ATOM   7295  C CA  . TYR B 1 482 ? 130.045 92.841  114.263 1.00 8.34  ? 461  TYR B CA  1 
ATOM   7296  C C   . TYR B 1 482 ? 129.125 92.120  115.242 1.00 8.34  ? 461  TYR B C   1 
ATOM   7297  O O   . TYR B 1 482 ? 129.297 92.221  116.458 1.00 8.34  ? 461  TYR B O   1 
ATOM   7298  C CB  . TYR B 1 482 ? 131.092 91.888  113.681 1.00 8.34  ? 461  TYR B CB  1 
ATOM   7299  C CG  . TYR B 1 482 ? 130.515 90.776  112.865 1.00 8.34  ? 461  TYR B CG  1 
ATOM   7300  C CD1 . TYR B 1 482 ? 130.060 91.028  111.582 1.00 8.34  ? 461  TYR B CD1 1 
ATOM   7301  C CD2 . TYR B 1 482 ? 130.401 89.500  113.354 1.00 8.34  ? 461  TYR B CD2 1 
ATOM   7302  C CE1 . TYR B 1 482 ? 129.531 90.041  110.806 1.00 8.34  ? 461  TYR B CE1 1 
ATOM   7303  C CE2 . TYR B 1 482 ? 129.862 88.504  112.578 1.00 8.34  ? 461  TYR B CE2 1 
ATOM   7304  C CZ  . TYR B 1 482 ? 129.424 88.783  111.308 1.00 8.34  ? 461  TYR B CZ  1 
ATOM   7305  O OH  . TYR B 1 482 ? 128.881 87.802  110.519 1.00 8.34  ? 461  TYR B OH  1 
ATOM   7306  N N   . HIS B 1 483 ? 128.149 91.388  114.697 1.00 12.09 ? 462  HIS B N   1 
ATOM   7307  C CA  . HIS B 1 483 ? 127.157 90.652  115.491 1.00 12.09 ? 462  HIS B CA  1 
ATOM   7308  C C   . HIS B 1 483 ? 126.439 91.539  116.502 1.00 12.09 ? 462  HIS B C   1 
ATOM   7309  O O   . HIS B 1 483 ? 126.187 91.138  117.640 1.00 12.09 ? 462  HIS B O   1 
ATOM   7310  C CB  . HIS B 1 483 ? 127.765 89.452  116.216 1.00 12.09 ? 462  HIS B CB  1 
ATOM   7311  C CG  . HIS B 1 483 ? 127.937 88.243  115.353 1.00 12.09 ? 462  HIS B CG  1 
ATOM   7312  N ND1 . HIS B 1 483 ? 126.880 87.637  114.708 1.00 12.09 ? 462  HIS B ND1 1 
ATOM   7313  C CD2 . HIS B 1 483 ? 129.027 87.488  115.080 1.00 12.09 ? 462  HIS B CD2 1 
ATOM   7314  C CE1 . HIS B 1 483 ? 127.321 86.587  114.038 1.00 12.09 ? 462  HIS B CE1 1 
ATOM   7315  N NE2 . HIS B 1 483 ? 128.621 86.477  114.244 1.00 12.09 ? 462  HIS B NE2 1 
ATOM   7316  N N   . ALA B 1 484 ? 126.098 92.753  116.096 1.00 11.37 ? 463  ALA B N   1 
ATOM   7317  C CA  . ALA B 1 484 ? 125.181 93.578  116.867 1.00 11.37 ? 463  ALA B CA  1 
ATOM   7318  C C   . ALA B 1 484 ? 123.797 93.468  116.244 1.00 11.37 ? 463  ALA B C   1 
ATOM   7319  O O   . ALA B 1 484 ? 123.639 93.681  115.038 1.00 11.37 ? 463  ALA B O   1 
ATOM   7320  C CB  . ALA B 1 484 ? 125.643 95.033  116.911 1.00 11.37 ? 463  ALA B CB  1 
ATOM   7321  N N   . TYR B 1 485 ? 122.801 93.132  117.059 1.00 13.07 ? 464  TYR B N   1 
ATOM   7322  C CA  . TYR B 1 485 ? 121.427 92.952  116.591 1.00 13.07 ? 464  TYR B CA  1 
ATOM   7323  C C   . TYR B 1 485 ? 120.464 93.814  117.399 1.00 13.07 ? 464  TYR B C   1 
ATOM   7324  O O   . TYR B 1 485 ? 119.580 93.300  118.089 1.00 13.07 ? 464  TYR B O   1 
ATOM   7325  C CB  . TYR B 1 485 ? 121.021 91.483  116.666 1.00 13.07 ? 464  TYR B CB  1 
ATOM   7326  C CG  . TYR B 1 485 ? 121.866 90.575  115.815 1.00 13.07 ? 464  TYR B CG  1 
ATOM   7327  C CD1 . TYR B 1 485 ? 121.519 90.307  114.499 1.00 13.07 ? 464  TYR B CD1 1 
ATOM   7328  C CD2 . TYR B 1 485 ? 123.013 89.988  116.324 1.00 13.07 ? 464  TYR B CD2 1 
ATOM   7329  C CE1 . TYR B 1 485 ? 122.294 89.479  113.715 1.00 13.07 ? 464  TYR B CE1 1 
ATOM   7330  C CE2 . TYR B 1 485 ? 123.792 89.161  115.549 1.00 13.07 ? 464  TYR B CE2 1 
ATOM   7331  C CZ  . TYR B 1 485 ? 123.430 88.910  114.246 1.00 13.07 ? 464  TYR B CZ  1 
ATOM   7332  O OH  . TYR B 1 485 ? 124.210 88.081  113.478 1.00 13.07 ? 464  TYR B OH  1 
ATOM   7333  N N   . PRO B 1 486 ? 120.599 95.135  117.330 1.00 9.65  ? 465  PRO B N   1 
ATOM   7334  C CA  . PRO B 1 486 ? 119.637 95.995  118.017 1.00 9.65  ? 465  PRO B CA  1 
ATOM   7335  C C   . PRO B 1 486 ? 118.253 95.871  117.402 1.00 9.65  ? 465  PRO B C   1 
ATOM   7336  O O   . PRO B 1 486 ? 118.095 95.595  116.211 1.00 9.65  ? 465  PRO B O   1 
ATOM   7337  C CB  . PRO B 1 486 ? 120.212 97.398  117.817 1.00 9.65  ? 465  PRO B CB  1 
ATOM   7338  C CG  . PRO B 1 486 ? 121.018 97.285  116.582 1.00 9.65  ? 465  PRO B CG  1 
ATOM   7339  C CD  . PRO B 1 486 ? 121.605 95.924  116.600 1.00 9.65  ? 465  PRO B CD  1 
ATOM   7340  N N   . ALA B 1 487 ? 117.239 96.080  118.238 1.00 9.61  ? 466  ALA B N   1 
ATOM   7341  C CA  . ALA B 1 487 ? 115.865 95.886  117.801 1.00 9.61  ? 466  ALA B CA  1 
ATOM   7342  C C   . ALA B 1 487 ? 115.411 96.924  116.786 1.00 9.61  ? 466  ALA B C   1 
ATOM   7343  O O   . ALA B 1 487 ? 114.355 96.739  116.176 1.00 9.61  ? 466  ALA B O   1 
ATOM   7344  C CB  . ALA B 1 487 ? 114.924 95.895  119.007 1.00 9.61  ? 466  ALA B CB  1 
ATOM   7345  N N   . HIS B 1 488 ? 116.176 97.991  116.577 1.00 6.32  ? 467  HIS B N   1 
ATOM   7346  C CA  . HIS B 1 488 ? 115.754 99.094  115.727 1.00 6.32  ? 467  HIS B CA  1 
ATOM   7347  C C   . HIS B 1 488 ? 116.520 99.165  114.413 1.00 6.32  ? 467  HIS B C   1 
ATOM   7348  O O   . HIS B 1 488 ? 116.299 100.097 113.636 1.00 6.32  ? 467  HIS B O   1 
ATOM   7349  C CB  . HIS B 1 488 ? 115.897 100.413 116.499 1.00 6.32  ? 467  HIS B CB  1 
ATOM   7350  C CG  . HIS B 1 488 ? 115.113 101.550 115.922 1.00 6.32  ? 467  HIS B CG  1 
ATOM   7351  N ND1 . HIS B 1 488 ? 113.737 101.577 115.920 1.00 6.32  ? 467  HIS B ND1 1 
ATOM   7352  C CD2 . HIS B 1 488 ? 115.510 102.717 115.368 1.00 6.32  ? 467  HIS B CD2 1 
ATOM   7353  C CE1 . HIS B 1 488 ? 113.320 102.701 115.368 1.00 6.32  ? 467  HIS B CE1 1 
ATOM   7354  N NE2 . HIS B 1 488 ? 114.377 103.411 115.024 1.00 6.32  ? 467  HIS B NE2 1 
ATOM   7355  N N   . ALA B 1 489 ? 117.401 98.207  114.135 1.00 8.34  ? 468  ALA B N   1 
ATOM   7356  C CA  . ALA B 1 489 ? 118.174 98.179  112.895 1.00 8.34  ? 468  ALA B CA  1 
ATOM   7357  C C   . ALA B 1 489 ? 117.649 97.061  112.001 1.00 8.34  ? 468  ALA B C   1 
ATOM   7358  O O   . ALA B 1 489 ? 117.730 95.882  112.357 1.00 8.34  ? 468  ALA B O   1 
ATOM   7359  C CB  . ALA B 1 489 ? 119.660 97.990  113.185 1.00 8.34  ? 468  ALA B CB  1 
ATOM   7360  N N   . ALA B 1 490 ? 117.127 97.434  110.836 1.00 10.31 ? 469  ALA B N   1 
ATOM   7361  C CA  . ALA B 1 490 ? 116.551 96.475  109.901 1.00 10.31 ? 469  ALA B CA  1 
ATOM   7362  C C   . ALA B 1 490 ? 117.566 95.425  109.485 1.00 10.31 ? 469  ALA B C   1 
ATOM   7363  O O   . ALA B 1 490 ? 118.589 95.742  108.874 1.00 10.31 ? 469  ALA B O   1 
ATOM   7364  C CB  . ALA B 1 490 ? 116.020 97.208  108.669 1.00 10.31 ? 469  ALA B CB  1 
ATOM   7365  N N   . PHE B 1 491 ? 117.269 94.170  109.805 1.00 14.89 ? 470  PHE B N   1 
ATOM   7366  C CA  . PHE B 1 491 ? 118.135 93.046  109.476 1.00 14.89 ? 470  PHE B CA  1 
ATOM   7367  C C   . PHE B 1 491 ? 117.546 92.289  108.297 1.00 14.89 ? 470  PHE B C   1 
ATOM   7368  O O   . PHE B 1 491 ? 116.382 91.877  108.337 1.00 14.89 ? 470  PHE B O   1 
ATOM   7369  C CB  . PHE B 1 491 ? 118.298 92.114  110.676 1.00 14.89 ? 470  PHE B CB  1 
ATOM   7370  C CG  . PHE B 1 491 ? 119.049 90.860  110.367 1.00 14.89 ? 470  PHE B CG  1 
ATOM   7371  C CD1 . PHE B 1 491 ? 120.429 90.867  110.310 1.00 14.89 ? 470  PHE B CD1 1 
ATOM   7372  C CD2 . PHE B 1 491 ? 118.377 89.671  110.140 1.00 14.89 ? 470  PHE B CD2 1 
ATOM   7373  C CE1 . PHE B 1 491 ? 121.127 89.717  110.029 1.00 14.89 ? 470  PHE B CE1 1 
ATOM   7374  C CE2 . PHE B 1 491 ? 119.072 88.515  109.856 1.00 14.89 ? 470  PHE B CE2 1 
ATOM   7375  C CZ  . PHE B 1 491 ? 120.450 88.539  109.801 1.00 14.89 ? 470  PHE B CZ  1 
ATOM   7376  N N   . GLY B 1 492 ? 118.349 92.102  107.258 1.00 18.35 ? 471  GLY B N   1 
ATOM   7377  C CA  . GLY B 1 492 ? 117.931 91.302  106.124 1.00 18.35 ? 471  GLY B CA  1 
ATOM   7378  C C   . GLY B 1 492 ? 119.066 91.184  105.134 1.00 18.35 ? 471  GLY B C   1 
ATOM   7379  O O   . GLY B 1 492 ? 120.185 91.641  105.378 1.00 18.35 ? 471  GLY B O   1 
ATOM   7380  N N   . GLY B 1 493 ? 118.764 90.550  104.013 1.00 17.03 ? 472  GLY B N   1 
ATOM   7381  C CA  . GLY B 1 493 ? 119.715 90.441  102.925 1.00 17.03 ? 472  GLY B CA  1 
ATOM   7382  C C   . GLY B 1 493 ? 118.984 90.467  101.603 1.00 17.03 ? 472  GLY B C   1 
ATOM   7383  O O   . GLY B 1 493 ? 117.823 90.065  101.508 1.00 17.03 ? 472  GLY B O   1 
ATOM   7384  N N   . TYR B 1 494 ? 119.672 90.962  100.572 1.00 10.07 ? 473  TYR B N   1 
ATOM   7385  C CA  . TYR B 1 494 ? 119.086 91.017  99.233  1.00 10.07 ? 473  TYR B CA  1 
ATOM   7386  C C   . TYR B 1 494 ? 120.024 90.376  98.215  1.00 10.07 ? 473  TYR B C   1 
ATOM   7387  O O   . TYR B 1 494 ? 120.750 91.048  97.480  1.00 10.07 ? 473  TYR B O   1 
ATOM   7388  C CB  . TYR B 1 494 ? 118.713 92.442  98.848  1.00 10.07 ? 473  TYR B CB  1 
ATOM   7389  C CG  . TYR B 1 494 ? 119.694 93.545  99.190  1.00 10.07 ? 473  TYR B CG  1 
ATOM   7390  C CD1 . TYR B 1 494 ? 120.805 93.797  98.397  1.00 10.07 ? 473  TYR B CD1 1 
ATOM   7391  C CD2 . TYR B 1 494 ? 119.460 94.387  100.267 1.00 10.07 ? 473  TYR B CD2 1 
ATOM   7392  C CE1 . TYR B 1 494 ? 121.664 94.822  98.688  1.00 10.07 ? 473  TYR B CE1 1 
ATOM   7393  C CE2 . TYR B 1 494 ? 120.313 95.416  100.563 1.00 10.07 ? 473  TYR B CE2 1 
ATOM   7394  C CZ  . TYR B 1 494 ? 121.410 95.628  99.773  1.00 10.07 ? 473  TYR B CZ  1 
ATOM   7395  O OH  . TYR B 1 494 ? 122.260 96.653  100.074 1.00 10.07 ? 473  TYR B OH  1 
ATOM   7396  N N   . LYS B 1 495 ? 119.968 89.052  98.183  1.00 17.09 ? 474  LYS B N   1 
ATOM   7397  C CA  . LYS B 1 495 ? 120.496 88.161  97.159  1.00 17.09 ? 474  LYS B CA  1 
ATOM   7398  C C   . LYS B 1 495 ? 119.722 86.875  97.384  1.00 17.09 ? 474  LYS B C   1 
ATOM   7399  O O   . LYS B 1 495 ? 118.625 86.923  97.948  1.00 17.09 ? 474  LYS B O   1 
ATOM   7400  C CB  . LYS B 1 495 ? 122.018 87.990  97.236  1.00 17.09 ? 474  LYS B CB  1 
ATOM   7401  C CG  . LYS B 1 495 ? 122.775 89.072  96.461  1.00 17.09 ? 474  LYS B CG  1 
ATOM   7402  C CD  . LYS B 1 495 ? 124.238 89.177  96.833  1.00 17.09 ? 474  LYS B CD  1 
ATOM   7403  C CE  . LYS B 1 495 ? 125.064 88.062  96.248  1.00 17.09 ? 474  LYS B CE  1 
ATOM   7404  N NZ  . LYS B 1 495 ? 126.495 88.292  96.563  1.00 17.09 ? 474  LYS B NZ  1 
ATOM   7405  N N   . GLN B 1 496 ? 120.233 85.729  96.949  1.00 23.05 ? 475  GLN B N   1 
ATOM   7406  C CA  . GLN B 1 496 ? 119.501 84.500  97.225  1.00 23.05 ? 475  GLN B CA  1 
ATOM   7407  C C   . GLN B 1 496 ? 119.633 84.232  98.725  1.00 23.05 ? 475  GLN B C   1 
ATOM   7408  O O   . GLN B 1 496 ? 120.262 83.261  99.153  1.00 23.05 ? 475  GLN B O   1 
ATOM   7409  C CB  . GLN B 1 496 ? 120.046 83.373  96.330  1.00 23.05 ? 475  GLN B CB  1 
ATOM   7410  C CG  . GLN B 1 496 ? 119.301 82.032  96.298  1.00 23.05 ? 475  GLN B CG  1 
ATOM   7411  C CD  . GLN B 1 496 ? 119.703 81.055  97.381  1.00 23.05 ? 475  GLN B CD  1 
ATOM   7412  O OE1 . GLN B 1 496 ? 120.838 81.058  97.851  1.00 23.05 ? 475  GLN B OE1 1 
ATOM   7413  N NE2 . GLN B 1 496 ? 118.780 80.181  97.753  1.00 23.05 ? 475  GLN B NE2 1 
ATOM   7414  N N   . SER B 1 497 ? 119.070 85.145  99.536  1.00 21.49 ? 476  SER B N   1 
ATOM   7415  C CA  . SER B 1 497 ? 119.167 85.084  100.989 1.00 21.49 ? 476  SER B CA  1 
ATOM   7416  C C   . SER B 1 497 ? 117.899 85.559  101.698 1.00 21.49 ? 476  SER B C   1 
ATOM   7417  O O   . SER B 1 497 ? 117.955 85.868  102.893 1.00 21.49 ? 476  SER B O   1 
ATOM   7418  C CB  . SER B 1 497 ? 120.357 85.906  101.490 1.00 21.49 ? 476  SER B CB  1 
ATOM   7419  O OG  . SER B 1 497 ? 121.580 85.363  101.027 1.00 21.49 ? 476  SER B OG  1 
ATOM   7420  N N   . GLY B 1 498 ? 116.770 85.652  101.007 1.00 23.38 ? 477  GLY B N   1 
ATOM   7421  C CA  . GLY B 1 498 ? 115.493 85.899  101.649 1.00 23.38 ? 477  GLY B CA  1 
ATOM   7422  C C   . GLY B 1 498 ? 114.819 87.164  101.150 1.00 23.38 ? 477  GLY B C   1 
ATOM   7423  O O   . GLY B 1 498 ? 115.329 87.884  100.292 1.00 23.38 ? 477  GLY B O   1 
ATOM   7424  N N   . ILE B 1 499 ? 113.631 87.413  101.710 1.00 22.79 ? 478  ILE B N   1 
ATOM   7425  C CA  . ILE B 1 499 ? 112.785 88.541  101.328 1.00 22.79 ? 478  ILE B CA  1 
ATOM   7426  C C   . ILE B 1 499 ? 112.170 89.172  102.571 1.00 22.79 ? 478  ILE B C   1 
ATOM   7427  O O   . ILE B 1 499 ? 111.215 88.633  103.139 1.00 22.79 ? 478  ILE B O   1 
ATOM   7428  C CB  . ILE B 1 499 ? 111.668 88.111  100.355 1.00 22.79 ? 478  ILE B CB  1 
ATOM   7429  C CG1 . ILE B 1 499 ? 112.196 87.165  99.272  1.00 22.79 ? 478  ILE B CG1 1 
ATOM   7430  C CG2 . ILE B 1 499 ? 111.029 89.332  99.714  1.00 22.79 ? 478  ILE B CG2 1 
ATOM   7431  C CD1 . ILE B 1 499 ? 111.117 86.359  98.596  1.00 22.79 ? 478  ILE B CD1 1 
ATOM   7432  N N   . GLY B 1 500 ? 112.689 90.316  102.994 1.00 20.82 ? 479  GLY B N   1 
ATOM   7433  C CA  . GLY B 1 500 ? 112.102 91.038  104.100 1.00 20.82 ? 479  GLY B CA  1 
ATOM   7434  C C   . GLY B 1 500 ? 113.163 91.686  104.963 1.00 20.82 ? 479  GLY B C   1 
ATOM   7435  O O   . GLY B 1 500 ? 114.342 91.719  104.619 1.00 20.82 ? 479  GLY B O   1 
ATOM   7436  N N   . ARG B 1 501 ? 112.724 92.209  106.107 1.00 15.57 ? 480  ARG B N   1 
ATOM   7437  C CA  . ARG B 1 501 ? 113.605 92.930  107.024 1.00 15.57 ? 480  ARG B CA  1 
ATOM   7438  C C   . ARG B 1 501 ? 113.137 92.659  108.447 1.00 15.57 ? 480  ARG B C   1 
ATOM   7439  O O   . ARG B 1 501 ? 112.031 93.060  108.813 1.00 15.57 ? 480  ARG B O   1 
ATOM   7440  C CB  . ARG B 1 501 ? 113.597 94.430  106.736 1.00 15.57 ? 480  ARG B CB  1 
ATOM   7441  C CG  . ARG B 1 501 ? 114.225 94.835  105.423 1.00 15.57 ? 480  ARG B CG  1 
ATOM   7442  C CD  . ARG B 1 501 ? 115.711 95.061  105.590 1.00 15.57 ? 480  ARG B CD  1 
ATOM   7443  N NE  . ARG B 1 501 ? 116.397 95.152  104.308 1.00 15.57 ? 480  ARG B NE  1 
ATOM   7444  C CZ  . ARG B 1 501 ? 116.669 94.109  103.534 1.00 15.57 ? 480  ARG B CZ  1 
ATOM   7445  N NH1 . ARG B 1 501 ? 116.307 92.893  103.904 1.00 15.57 ? 480  ARG B NH1 1 
ATOM   7446  N NH2 . ARG B 1 501 ? 117.294 94.284  102.383 1.00 15.57 ? 480  ARG B NH2 1 
ATOM   7447  N N   . GLU B 1 502 ? 113.968 91.992  109.245 1.00 15.88 ? 481  GLU B N   1 
ATOM   7448  C CA  . GLU B 1 502 ? 113.659 91.785  110.650 1.00 15.88 ? 481  GLU B CA  1 
ATOM   7449  C C   . GLU B 1 502 ? 114.219 92.926  111.499 1.00 15.88 ? 481  GLU B C   1 
ATOM   7450  O O   . GLU B 1 502 ? 114.913 93.820  111.011 1.00 15.88 ? 481  GLU B O   1 
ATOM   7451  C CB  . GLU B 1 502 ? 114.203 90.442  111.139 1.00 15.88 ? 481  GLU B CB  1 
ATOM   7452  C CG  . GLU B 1 502 ? 113.431 89.222  110.667 1.00 15.88 ? 481  GLU B CG  1 
ATOM   7453  C CD  . GLU B 1 502 ? 114.074 88.547  109.476 1.00 15.88 ? 481  GLU B CD  1 
ATOM   7454  O OE1 . GLU B 1 502 ? 115.189 88.954  109.091 1.00 15.88 ? 481  GLU B OE1 1 
ATOM   7455  O OE2 . GLU B 1 502 ? 113.467 87.605  108.927 1.00 15.88 ? 481  GLU B OE2 1 
ATOM   7456  N N   . THR B 1 503 ? 113.915 92.879  112.798 1.00 11.20 ? 482  THR B N   1 
ATOM   7457  C CA  . THR B 1 503 ? 114.480 93.788  113.803 1.00 11.20 ? 482  THR B CA  1 
ATOM   7458  C C   . THR B 1 503 ? 114.248 95.255  113.447 1.00 11.20 ? 482  THR B C   1 
ATOM   7459  O O   . THR B 1 503 ? 115.121 96.100  113.648 1.00 11.20 ? 482  THR B O   1 
ATOM   7460  C CB  . THR B 1 503 ? 115.975 93.532  114.020 1.00 11.20 ? 482  THR B CB  1 
ATOM   7461  O OG1 . THR B 1 503 ? 116.680 93.698  112.786 1.00 11.20 ? 482  THR B OG1 1 
ATOM   7462  C CG2 . THR B 1 503 ? 116.208 92.121  114.517 1.00 11.20 ? 482  THR B CG2 1 
ATOM   7463  N N   . HIS B 1 504 ? 113.070 95.567  112.917 1.00 8.49  ? 483  HIS B N   1 
ATOM   7464  C CA  . HIS B 1 504 ? 112.764 96.942  112.548 1.00 8.49  ? 483  HIS B CA  1 
ATOM   7465  C C   . HIS B 1 504 ? 111.256 97.115  112.468 1.00 8.49  ? 483  HIS B C   1 
ATOM   7466  O O   . HIS B 1 504 ? 110.499 96.144  112.422 1.00 8.49  ? 483  HIS B O   1 
ATOM   7467  C CB  . HIS B 1 504 ? 113.425 97.323  111.224 1.00 8.49  ? 483  HIS B CB  1 
ATOM   7468  C CG  . HIS B 1 504 ? 113.550 98.799  111.016 1.00 8.49  ? 483  HIS B CG  1 
ATOM   7469  N ND1 . HIS B 1 504 ? 113.720 99.363  109.772 1.00 8.49  ? 483  HIS B ND1 1 
ATOM   7470  C CD2 . HIS B 1 504 ? 113.522 99.828  111.895 1.00 8.49  ? 483  HIS B CD2 1 
ATOM   7471  C CE1 . HIS B 1 504 ? 113.791 100.676 109.892 1.00 8.49  ? 483  HIS B CE1 1 
ATOM   7472  N NE2 . HIS B 1 504 ? 113.672 100.984 111.170 1.00 8.49  ? 483  HIS B NE2 1 
ATOM   7473  N N   . LYS B 1 505 ? 110.828 98.376  112.447 1.00 5.90  ? 484  LYS B N   1 
ATOM   7474  C CA  . LYS B 1 505 ? 109.411 98.691  112.328 1.00 5.90  ? 484  LYS B CA  1 
ATOM   7475  C C   . LYS B 1 505 ? 108.866 98.445  110.927 1.00 5.90  ? 484  LYS B C   1 
ATOM   7476  O O   . LYS B 1 505 ? 107.646 98.481  110.746 1.00 5.90  ? 484  LYS B O   1 
ATOM   7477  C CB  . LYS B 1 505 ? 109.163 100.144 112.734 1.00 5.90  ? 484  LYS B CB  1 
ATOM   7478  C CG  . LYS B 1 505 ? 110.128 101.134 112.124 1.00 5.90  ? 484  LYS B CG  1 
ATOM   7479  C CD  . LYS B 1 505 ? 110.063 102.460 112.840 1.00 5.90  ? 484  LYS B CD  1 
ATOM   7480  C CE  . LYS B 1 505 ? 108.678 103.060 112.743 1.00 5.90  ? 484  LYS B CE  1 
ATOM   7481  N NZ  . LYS B 1 505 ? 108.564 104.316 113.526 1.00 5.90  ? 484  LYS B NZ  1 
ATOM   7482  N N   . MET B 1 506 ? 109.726 98.216  109.935 1.00 7.73  ? 485  MET B N   1 
ATOM   7483  C CA  . MET B 1 506 ? 109.232 97.794  108.629 1.00 7.73  ? 485  MET B CA  1 
ATOM   7484  C C   . MET B 1 506 ? 108.618 96.405  108.691 1.00 7.73  ? 485  MET B C   1 
ATOM   7485  O O   . MET B 1 506 ? 107.763 96.070  107.868 1.00 7.73  ? 485  MET B O   1 
ATOM   7486  C CB  . MET B 1 506 ? 110.355 97.814  107.595 1.00 7.73  ? 485  MET B CB  1 
ATOM   7487  C CG  . MET B 1 506 ? 111.294 98.987  107.713 1.00 7.73  ? 485  MET B CG  1 
ATOM   7488  S SD  . MET B 1 506 ? 112.942 98.623  107.069 1.00 7.73  ? 485  MET B SD  1 
ATOM   7489  C CE  . MET B 1 506 ? 112.582 98.249  105.351 1.00 7.73  ? 485  MET B CE  1 
ATOM   7490  N N   . MET B 1 507 ? 109.040 95.587  109.649 1.00 7.42  ? 486  MET B N   1 
ATOM   7491  C CA  . MET B 1 507 ? 108.527 94.232  109.757 1.00 7.42  ? 486  MET B CA  1 
ATOM   7492  C C   . MET B 1 507 ? 107.146 94.189  110.398 1.00 7.42  ? 486  MET B C   1 
ATOM   7493  O O   . MET B 1 507 ? 106.448 93.179  110.273 1.00 7.42  ? 486  MET B O   1 
ATOM   7494  C CB  . MET B 1 507 ? 109.518 93.372  110.547 1.00 7.42  ? 486  MET B CB  1 
ATOM   7495  C CG  . MET B 1 507 ? 109.152 91.911  110.656 1.00 7.42  ? 486  MET B CG  1 
ATOM   7496  S SD  . MET B 1 507 ? 110.396 90.942  111.513 1.00 7.42  ? 486  MET B SD  1 
ATOM   7497  C CE  . MET B 1 507 ? 109.611 89.338  111.547 1.00 7.42  ? 486  MET B CE  1 
ATOM   7498  N N   . LEU B 1 508 ? 106.723 95.262  111.065 1.00 5.18  ? 487  LEU B N   1 
ATOM   7499  C CA  . LEU B 1 508 ? 105.341 95.323  111.517 1.00 5.18  ? 487  LEU B CA  1 
ATOM   7500  C C   . LEU B 1 508 ? 104.382 95.401  110.342 1.00 5.18  ? 487  LEU B C   1 
ATOM   7501  O O   . LEU B 1 508 ? 103.238 94.951  110.447 1.00 5.18  ? 487  LEU B O   1 
ATOM   7502  C CB  . LEU B 1 508 ? 105.127 96.516  112.438 1.00 5.18  ? 487  LEU B CB  1 
ATOM   7503  C CG  . LEU B 1 508 ? 103.991 96.283  113.422 1.00 5.18  ? 487  LEU B CG  1 
ATOM   7504  C CD1 . LEU B 1 508 ? 104.407 95.207  114.374 1.00 5.18  ? 487  LEU B CD1 1 
ATOM   7505  C CD2 . LEU B 1 508 ? 103.638 97.548  114.167 1.00 5.18  ? 487  LEU B CD2 1 
ATOM   7506  N N   . ASP B 1 509 ? 104.825 95.970  109.224 1.00 6.49  ? 488  ASP B N   1 
ATOM   7507  C CA  . ASP B 1 509 ? 103.993 96.064  108.037 1.00 6.49  ? 488  ASP B CA  1 
ATOM   7508  C C   . ASP B 1 509 ? 103.998 94.788  107.214 1.00 6.49  ? 488  ASP B C   1 
ATOM   7509  O O   . ASP B 1 509 ? 103.147 94.636  106.333 1.00 6.49  ? 488  ASP B O   1 
ATOM   7510  C CB  . ASP B 1 509 ? 104.452 97.235  107.170 1.00 6.49  ? 488  ASP B CB  1 
ATOM   7511  C CG  . ASP B 1 509 ? 104.033 98.573  107.734 1.00 6.49  ? 488  ASP B CG  1 
ATOM   7512  O OD1 . ASP B 1 509 ? 103.019 98.618  108.460 1.00 6.49  ? 488  ASP B OD1 1 
ATOM   7513  O OD2 . ASP B 1 509 ? 104.714 99.580  107.452 1.00 6.49  ? 488  ASP B OD2 1 
ATOM   7514  N N   . HIS B 1 510 ? 104.932 93.873  107.471 1.00 7.13  ? 489  HIS B N   1 
ATOM   7515  C CA  . HIS B 1 510 ? 104.942 92.607  106.754 1.00 7.13  ? 489  HIS B CA  1 
ATOM   7516  C C   . HIS B 1 510 ? 103.849 91.675  107.240 1.00 7.13  ? 489  HIS B C   1 
ATOM   7517  O O   . HIS B 1 510 ? 103.478 90.744  106.520 1.00 7.13  ? 489  HIS B O   1 
ATOM   7518  C CB  . HIS B 1 510 ? 106.303 91.931  106.894 1.00 7.13  ? 489  HIS B CB  1 
ATOM   7519  C CG  . HIS B 1 510 ? 107.247 92.243  105.779 1.00 7.13  ? 489  HIS B CG  1 
ATOM   7520  N ND1 . HIS B 1 510 ? 106.984 91.915  104.467 1.00 7.13  ? 489  HIS B ND1 1 
ATOM   7521  C CD2 . HIS B 1 510 ? 108.456 92.853  105.778 1.00 7.13  ? 489  HIS B CD2 1 
ATOM   7522  C CE1 . HIS B 1 510 ? 107.988 92.310  103.706 1.00 7.13  ? 489  HIS B CE1 1 
ATOM   7523  N NE2 . HIS B 1 510 ? 108.894 92.884  104.477 1.00 7.13  ? 489  HIS B NE2 1 
ATOM   7524  N N   . TYR B 1 511 ? 103.332 91.905  108.442 1.00 4.04  ? 490  TYR B N   1 
ATOM   7525  C CA  . TYR B 1 511 ? 102.234 91.135  109.004 1.00 4.04  ? 490  TYR B CA  1 
ATOM   7526  C C   . TYR B 1 511 ? 100.961 91.967  109.067 1.00 4.04  ? 490  TYR B C   1 
ATOM   7527  O O   . TYR B 1 511 ? 100.142 91.803  109.971 1.00 4.04  ? 490  TYR B O   1 
ATOM   7528  C CB  . TYR B 1 511 ? 102.606 90.612  110.388 1.00 4.04  ? 490  TYR B CB  1 
ATOM   7529  C CG  . TYR B 1 511 ? 103.792 89.687  110.373 1.00 4.04  ? 490  TYR B CG  1 
ATOM   7530  C CD1 . TYR B 1 511 ? 103.672 88.386  109.918 1.00 4.04  ? 490  TYR B CD1 1 
ATOM   7531  C CD2 . TYR B 1 511 ? 105.032 90.117  110.798 1.00 4.04  ? 490  TYR B CD2 1 
ATOM   7532  C CE1 . TYR B 1 511 ? 104.753 87.540  109.893 1.00 4.04  ? 490  TYR B CE1 1 
ATOM   7533  C CE2 . TYR B 1 511 ? 106.119 89.278  110.775 1.00 4.04  ? 490  TYR B CE2 1 
ATOM   7534  C CZ  . TYR B 1 511 ? 105.973 87.991  110.324 1.00 4.04  ? 490  TYR B CZ  1 
ATOM   7535  O OH  . TYR B 1 511 ? 107.056 87.149  110.303 1.00 4.04  ? 490  TYR B OH  1 
ATOM   7536  N N   . GLN B 1 512 ? 100.799 92.872  108.112 1.00 2.94  ? 491  GLN B N   1 
ATOM   7537  C CA  . GLN B 1 512 ? 99.655  93.762  108.047 1.00 2.94  ? 491  GLN B CA  1 
ATOM   7538  C C   . GLN B 1 512 ? 99.301  93.979  106.589 1.00 2.94  ? 491  GLN B C   1 
ATOM   7539  O O   . GLN B 1 512 ? 100.071 93.653  105.683 1.00 2.94  ? 491  GLN B O   1 
ATOM   7540  C CB  . GLN B 1 512 ? 99.943  95.106  108.717 1.00 2.94  ? 491  GLN B CB  1 
ATOM   7541  C CG  . GLN B 1 512 ? 99.483  95.221  110.146 1.00 2.94  ? 491  GLN B CG  1 
ATOM   7542  C CD  . GLN B 1 512 ? 100.045 96.447  110.809 1.00 2.94  ? 491  GLN B CD  1 
ATOM   7543  O OE1 . GLN B 1 512 ? 101.069 96.975  110.387 1.00 2.94  ? 491  GLN B OE1 1 
ATOM   7544  N NE2 . GLN B 1 512 ? 99.379  96.914  111.850 1.00 2.94  ? 491  GLN B NE2 1 
ATOM   7545  N N   . GLN B 1 513 ? 98.119  94.537  106.367 1.00 3.81  ? 492  GLN B N   1 
ATOM   7546  C CA  . GLN B 1 513 ? 97.689  94.893  105.027 1.00 3.81  ? 492  GLN B CA  1 
ATOM   7547  C C   . GLN B 1 513 ? 96.974  96.233  105.087 1.00 3.81  ? 492  GLN B C   1 
ATOM   7548  O O   . GLN B 1 513 ? 96.473  96.638  106.136 1.00 3.81  ? 492  GLN B O   1 
ATOM   7549  C CB  . GLN B 1 513 ? 96.797  93.807  104.421 1.00 3.81  ? 492  GLN B CB  1 
ATOM   7550  C CG  . GLN B 1 513 ? 95.583  93.478  105.246 1.00 3.81  ? 492  GLN B CG  1 
ATOM   7551  C CD  . GLN B 1 513 ? 94.956  92.173  104.835 1.00 3.81  ? 492  GLN B CD  1 
ATOM   7552  O OE1 . GLN B 1 513 ? 95.394  91.538  103.881 1.00 3.81  ? 492  GLN B OE1 1 
ATOM   7553  N NE2 . GLN B 1 513 ? 93.930  91.756  105.562 1.00 3.81  ? 492  GLN B NE2 1 
ATOM   7554  N N   . THR B 1 514 ? 96.947  96.925  103.958 1.00 4.97  ? 493  THR B N   1 
ATOM   7555  C CA  . THR B 1 514 ? 96.412  98.276  103.892 1.00 4.97  ? 493  THR B CA  1 
ATOM   7556  C C   . THR B 1 514 ? 94.997  98.260  103.333 1.00 4.97  ? 493  THR B C   1 
ATOM   7557  O O   . THR B 1 514 ? 94.761  97.750  102.235 1.00 4.97  ? 493  THR B O   1 
ATOM   7558  C CB  . THR B 1 514 ? 97.306  99.173  103.035 1.00 4.97  ? 493  THR B CB  1 
ATOM   7559  O OG1 . THR B 1 514 ? 97.407  98.629  101.715 1.00 4.97  ? 493  THR B OG1 1 
ATOM   7560  C CG2 . THR B 1 514 ? 98.693  99.270  103.637 1.00 4.97  ? 493  THR B CG2 1 
ATOM   7561  N N   . LYS B 1 515 ? 94.064  98.814  104.098 1.00 4.94  ? 494  LYS B N   1 
ATOM   7562  C CA  . LYS B 1 515 ? 92.720  99.119  103.626 1.00 4.94  ? 494  LYS B CA  1 
ATOM   7563  C C   . LYS B 1 515 ? 92.705  100.561 103.142 1.00 4.94  ? 494  LYS B C   1 
ATOM   7564  O O   . LYS B 1 515 ? 92.890  101.486 103.934 1.00 4.94  ? 494  LYS B O   1 
ATOM   7565  C CB  . LYS B 1 515 ? 91.689  98.910  104.731 1.00 4.94  ? 494  LYS B CB  1 
ATOM   7566  C CG  . LYS B 1 515 ? 90.281  99.325  104.348 1.00 4.94  ? 494  LYS B CG  1 
ATOM   7567  C CD  . LYS B 1 515 ? 89.710  98.496  103.225 1.00 4.94  ? 494  LYS B CD  1 
ATOM   7568  C CE  . LYS B 1 515 ? 89.435  97.086  103.680 1.00 4.94  ? 494  LYS B CE  1 
ATOM   7569  N NZ  . LYS B 1 515 ? 88.318  97.049  104.650 1.00 4.94  ? 494  LYS B NZ  1 
ATOM   7570  N N   . ASN B 1 516 ? 92.485  100.758 101.852 1.00 4.25  ? 495  ASN B N   1 
ATOM   7571  C CA  . ASN B 1 516 ? 92.436  102.092 101.271 1.00 4.25  ? 495  ASN B CA  1 
ATOM   7572  C C   . ASN B 1 516 ? 90.979  102.461 101.018 1.00 4.25  ? 495  ASN B C   1 
ATOM   7573  O O   . ASN B 1 516 ? 90.364  101.968 100.071 1.00 4.25  ? 495  ASN B O   1 
ATOM   7574  C CB  . ASN B 1 516 ? 93.252  102.145 99.985  1.00 4.25  ? 495  ASN B CB  1 
ATOM   7575  C CG  . ASN B 1 516 ? 93.113  103.464 99.265  1.00 4.25  ? 495  ASN B CG  1 
ATOM   7576  O OD1 . ASN B 1 516 ? 93.334  104.527 99.837  1.00 4.25  ? 495  ASN B OD1 1 
ATOM   7577  N ND2 . ASN B 1 516 ? 92.736  103.403 98.002  1.00 4.25  ? 495  ASN B ND2 1 
ATOM   7578  N N   . MET B 1 517 ? 90.433  103.329 101.859 1.00 3.70  ? 496  MET B N   1 
ATOM   7579  C CA  . MET B 1 517 ? 89.077  103.841 101.717 1.00 3.70  ? 496  MET B CA  1 
ATOM   7580  C C   . MET B 1 517 ? 89.146  105.202 101.036 1.00 3.70  ? 496  MET B C   1 
ATOM   7581  O O   . MET B 1 517 ? 89.546  106.186 101.658 1.00 3.70  ? 496  MET B O   1 
ATOM   7582  C CB  . MET B 1 517 ? 88.411  103.961 103.081 1.00 3.70  ? 496  MET B CB  1 
ATOM   7583  C CG  . MET B 1 517 ? 88.155  102.650 103.775 1.00 3.70  ? 496  MET B CG  1 
ATOM   7584  S SD  . MET B 1 517 ? 87.456  102.936 105.399 1.00 3.70  ? 496  MET B SD  1 
ATOM   7585  C CE  . MET B 1 517 ? 85.831  103.525 104.951 1.00 3.70  ? 496  MET B CE  1 
ATOM   7586  N N   . LEU B 1 518 ? 88.760  105.263 99.767  1.00 2.78  ? 497  LEU B N   1 
ATOM   7587  C CA  . LEU B 1 518 ? 88.831  106.500 98.990  1.00 2.78  ? 497  LEU B CA  1 
ATOM   7588  C C   . LEU B 1 518 ? 87.443  107.124 98.942  1.00 2.78  ? 497  LEU B C   1 
ATOM   7589  O O   . LEU B 1 518 ? 86.618  106.778 98.102  1.00 2.78  ? 497  LEU B O   1 
ATOM   7590  C CB  . LEU B 1 518 ? 89.381  106.235 97.596  1.00 2.78  ? 497  LEU B CB  1 
ATOM   7591  C CG  . LEU B 1 518 ? 89.784  107.494 96.838  1.00 2.78  ? 497  LEU B CG  1 
ATOM   7592  C CD1 . LEU B 1 518 ? 91.048  107.269 96.079  1.00 2.78  ? 497  LEU B CD1 1 
ATOM   7593  C CD2 . LEU B 1 518 ? 88.696  107.881 95.881  1.00 2.78  ? 497  LEU B CD2 1 
ATOM   7594  N N   . VAL B 1 519 ? 87.193  108.057 99.842  1.00 2.66  ? 498  VAL B N   1 
ATOM   7595  C CA  . VAL B 1 519 ? 85.887  108.682 99.983  1.00 2.66  ? 498  VAL B CA  1 
ATOM   7596  C C   . VAL B 1 519 ? 85.815  109.920 99.105  1.00 2.66  ? 498  VAL B C   1 
ATOM   7597  O O   . VAL B 1 519 ? 86.789  110.668 98.974  1.00 2.66  ? 498  VAL B O   1 
ATOM   7598  C CB  . VAL B 1 519 ? 85.609  109.029 101.455 1.00 2.66  ? 498  VAL B CB  1 
ATOM   7599  C CG1 . VAL B 1 519 ? 84.199  109.525 101.623 1.00 2.66  ? 498  VAL B CG1 1 
ATOM   7600  C CG2 . VAL B 1 519 ? 85.835  107.818 102.317 1.00 2.66  ? 498  VAL B CG2 1 
ATOM   7601  N N   . SER B 1 520 ? 84.659  110.126 98.485  1.00 3.56  ? 499  SER B N   1 
ATOM   7602  C CA  . SER B 1 520 ? 84.346  111.352 97.770  1.00 3.56  ? 499  SER B CA  1 
ATOM   7603  C C   . SER B 1 520 ? 83.234  112.087 98.495  1.00 3.56  ? 499  SER B C   1 
ATOM   7604  O O   . SER B 1 520 ? 82.291  111.468 98.996  1.00 3.56  ? 499  SER B O   1 
ATOM   7605  C CB  . SER B 1 520 ? 83.913  111.076 96.340  1.00 3.56  ? 499  SER B CB  1 
ATOM   7606  O OG  . SER B 1 520 ? 83.461  112.261 95.721  1.00 3.56  ? 499  SER B OG  1 
ATOM   7607  N N   . TYR B 1 521 ? 83.347  113.408 98.546  1.00 5.13  ? 500  TYR B N   1 
ATOM   7608  C CA  . TYR B 1 521 ? 82.413  114.221 99.296  1.00 5.13  ? 500  TYR B CA  1 
ATOM   7609  C C   . TYR B 1 521 ? 81.600  115.180 98.442  1.00 5.13  ? 500  TYR B C   1 
ATOM   7610  O O   . TYR B 1 521 ? 80.628  115.747 98.945  1.00 5.13  ? 500  TYR B O   1 
ATOM   7611  C CB  . TYR B 1 521 ? 83.164  115.001 100.379 1.00 5.13  ? 500  TYR B CB  1 
ATOM   7612  C CG  . TYR B 1 521 ? 83.741  114.094 101.433 1.00 5.13  ? 500  TYR B CG  1 
ATOM   7613  C CD1 . TYR B 1 521 ? 82.947  113.597 102.451 1.00 5.13  ? 500  TYR B CD1 1 
ATOM   7614  C CD2 . TYR B 1 521 ? 85.075  113.720 101.402 1.00 5.13  ? 500  TYR B CD2 1 
ATOM   7615  C CE1 . TYR B 1 521 ? 83.463  112.765 103.409 1.00 5.13  ? 500  TYR B CE1 1 
ATOM   7616  C CE2 . TYR B 1 521 ? 85.599  112.888 102.361 1.00 5.13  ? 500  TYR B CE2 1 
ATOM   7617  C CZ  . TYR B 1 521 ? 84.786  112.418 103.365 1.00 5.13  ? 500  TYR B CZ  1 
ATOM   7618  O OH  . TYR B 1 521 ? 85.288  111.588 104.334 1.00 5.13  ? 500  TYR B OH  1 
ATOM   7619  N N   . SER B 1 522 ? 81.951  115.368 97.180  1.00 7.78  ? 501  SER B N   1 
ATOM   7620  C CA  . SER B 1 522 ? 81.125  116.162 96.282  1.00 7.78  ? 501  SER B CA  1 
ATOM   7621  C C   . SER B 1 522 ? 79.959  115.322 95.778  1.00 7.78  ? 501  SER B C   1 
ATOM   7622  O O   . SER B 1 522 ? 80.187  114.291 95.137  1.00 7.78  ? 501  SER B O   1 
ATOM   7623  C CB  . SER B 1 522 ? 81.944  116.663 95.106  1.00 7.78  ? 501  SER B CB  1 
ATOM   7624  O OG  . SER B 1 522 ? 82.366  115.586 94.290  1.00 7.78  ? 501  SER B OG  1 
ATOM   7625  N N   . PRO B 1 523 ? 78.712  115.714 96.036  1.00 9.91  ? 502  PRO B N   1 
ATOM   7626  C CA  . PRO B 1 523 ? 77.551  114.960 95.554  1.00 9.91  ? 502  PRO B CA  1 
ATOM   7627  C C   . PRO B 1 523 ? 77.122  115.368 94.149  1.00 9.91  ? 502  PRO B C   1 
ATOM   7628  O O   . PRO B 1 523 ? 75.948  115.641 93.892  1.00 9.91  ? 502  PRO B O   1 
ATOM   7629  C CB  . PRO B 1 523 ? 76.479  115.297 96.593  1.00 9.91  ? 502  PRO B CB  1 
ATOM   7630  C CG  . PRO B 1 523 ? 76.811  116.693 96.994  1.00 9.91  ? 502  PRO B CG  1 
ATOM   7631  C CD  . PRO B 1 523 ? 78.310  116.856 96.874  1.00 9.91  ? 502  PRO B CD  1 
ATOM   7632  N N   . LYS B 1 524 ? 78.077  115.418 93.227  1.00 12.88 ? 503  LYS B N   1 
ATOM   7633  C CA  . LYS B 1 524 ? 77.816  115.834 91.856  1.00 12.88 ? 503  LYS B CA  1 
ATOM   7634  C C   . LYS B 1 524 ? 78.535  114.889 90.909  1.00 12.88 ? 503  LYS B C   1 
ATOM   7635  O O   . LYS B 1 524 ? 79.712  114.581 91.113  1.00 12.88 ? 503  LYS B O   1 
ATOM   7636  C CB  . LYS B 1 524 ? 78.269  117.278 91.617  1.00 12.88 ? 503  LYS B CB  1 
ATOM   7637  C CG  . LYS B 1 524 ? 77.313  118.323 92.168  1.00 12.88 ? 503  LYS B CG  1 
ATOM   7638  C CD  . LYS B 1 524 ? 78.031  119.625 92.484  1.00 12.88 ? 503  LYS B CD  1 
ATOM   7639  C CE  . LYS B 1 524 ? 78.584  119.626 93.904  1.00 12.88 ? 503  LYS B CE  1 
ATOM   7640  N NZ  . LYS B 1 524 ? 79.419  120.830 94.180  1.00 12.88 ? 503  LYS B NZ  1 
ATOM   7641  N N   . LYS B 1 525 ? 77.832  114.443 89.874  1.00 18.08 ? 504  LYS B N   1 
ATOM   7642  C CA  . LYS B 1 525 ? 78.380  113.435 88.987  1.00 18.08 ? 504  LYS B CA  1 
ATOM   7643  C C   . LYS B 1 525 ? 79.535  114.001 88.171  1.00 18.08 ? 504  LYS B C   1 
ATOM   7644  O O   . LYS B 1 525 ? 79.667  115.212 87.979  1.00 18.08 ? 504  LYS B O   1 
ATOM   7645  C CB  . LYS B 1 525 ? 77.295  112.888 88.062  1.00 18.08 ? 504  LYS B CB  1 
ATOM   7646  C CG  . LYS B 1 525 ? 76.704  113.900 87.105  1.00 18.08 ? 504  LYS B CG  1 
ATOM   7647  C CD  . LYS B 1 525 ? 75.586  113.274 86.290  1.00 18.08 ? 504  LYS B CD  1 
ATOM   7648  C CE  . LYS B 1 525 ? 75.022  114.243 85.268  1.00 18.08 ? 504  LYS B CE  1 
ATOM   7649  N NZ  . LYS B 1 525 ? 74.275  115.360 85.901  1.00 18.08 ? 504  LYS B NZ  1 
ATOM   7650  N N   . LEU B 1 526 ? 80.393  113.099 87.696  1.00 23.73 ? 505  LEU B N   1 
ATOM   7651  C CA  . LEU B 1 526 ? 81.548  113.521 86.915  1.00 23.73 ? 505  LEU B CA  1 
ATOM   7652  C C   . LEU B 1 526 ? 81.137  114.031 85.541  1.00 23.73 ? 505  LEU B C   1 
ATOM   7653  O O   . LEU B 1 526 ? 81.754  114.968 85.023  1.00 23.73 ? 505  LEU B O   1 
ATOM   7654  C CB  . LEU B 1 526 ? 82.543  112.366 86.765  1.00 23.73 ? 505  LEU B CB  1 
ATOM   7655  C CG  . LEU B 1 526 ? 83.490  112.039 87.926  1.00 23.73 ? 505  LEU B CG  1 
ATOM   7656  C CD1 . LEU B 1 526 ? 84.409  113.210 88.257  1.00 23.73 ? 505  LEU B CD1 1 
ATOM   7657  C CD2 . LEU B 1 526 ? 82.725  111.576 89.162  1.00 23.73 ? 505  LEU B CD2 1 
ATOM   7658  N N   . GLY B 1 527 ? 80.112  113.431 84.942  1.00 25.58 ? 506  GLY B N   1 
ATOM   7659  C CA  . GLY B 1 527 ? 79.594  113.901 83.674  1.00 25.58 ? 506  GLY B CA  1 
ATOM   7660  C C   . GLY B 1 527 ? 79.676  112.895 82.545  1.00 25.58 ? 506  GLY B C   1 
ATOM   7661  O O   . GLY B 1 527 ? 79.474  113.256 81.382  1.00 25.58 ? 506  GLY B O   1 
ATOM   7662  N N   . PHE B 1 528 ? 79.967  111.635 82.863  1.00 25.51 ? 507  PHE B N   1 
ATOM   7663  C CA  . PHE B 1 528 ? 80.074  110.617 81.826  1.00 25.51 ? 507  PHE B CA  1 
ATOM   7664  C C   . PHE B 1 528 ? 79.997  109.236 82.459  1.00 25.51 ? 507  PHE B C   1 
ATOM   7665  O O   . PHE B 1 528 ? 80.614  108.992 83.499  1.00 25.51 ? 507  PHE B O   1 
ATOM   7666  C CB  . PHE B 1 528 ? 81.371  110.767 81.019  1.00 25.51 ? 507  PHE B CB  1 
ATOM   7667  C CG  . PHE B 1 528 ? 82.622  110.734 81.847  1.00 25.51 ? 507  PHE B CG  1 
ATOM   7668  C CD1 . PHE B 1 528 ? 83.060  111.864 82.518  1.00 25.51 ? 507  PHE B CD1 1 
ATOM   7669  C CD2 . PHE B 1 528 ? 83.377  109.576 81.929  1.00 25.51 ? 507  PHE B CD2 1 
ATOM   7670  C CE1 . PHE B 1 528 ? 84.217  111.834 83.268  1.00 25.51 ? 507  PHE B CE1 1 
ATOM   7671  C CE2 . PHE B 1 528 ? 84.535  109.540 82.677  1.00 25.51 ? 507  PHE B CE2 1 
ATOM   7672  C CZ  . PHE B 1 528 ? 84.957  110.669 83.347  1.00 25.51 ? 507  PHE B CZ  1 
ATOM   7673  N N   . PHE B 1 529 ? 79.229  108.348 81.828  1.00 20.41 ? 508  PHE B N   1 
ATOM   7674  C CA  . PHE B 1 529 ? 79.014  106.984 82.319  1.00 20.41 ? 508  PHE B CA  1 
ATOM   7675  C C   . PHE B 1 529 ? 80.298  106.173 82.429  1.00 20.41 ? 508  PHE B C   1 
ATOM   7676  O O   . PHE B 1 529 ? 80.629  105.404 81.529  1.00 20.41 ? 508  PHE B O   1 
ATOM   7677  C CB  . PHE B 1 529 ? 78.034  106.243 81.412  1.00 20.41 ? 508  PHE B CB  1 
ATOM   7678  C CG  . PHE B 1 529 ? 76.728  106.952 81.223  1.00 20.41 ? 508  PHE B CG  1 
ATOM   7679  C CD1 . PHE B 1 529 ? 76.127  107.620 82.271  1.00 20.41 ? 508  PHE B CD1 1 
ATOM   7680  C CD2 . PHE B 1 529 ? 76.094  106.940 79.995  1.00 20.41 ? 508  PHE B CD2 1 
ATOM   7681  C CE1 . PHE B 1 529 ? 74.924  108.268 82.090  1.00 20.41 ? 508  PHE B CE1 1 
ATOM   7682  C CE2 . PHE B 1 529 ? 74.894  107.584 79.808  1.00 20.41 ? 508  PHE B CE2 1 
ATOM   7683  C CZ  . PHE B 1 529 ? 74.306  108.248 80.856  1.00 20.41 ? 508  PHE B CZ  1 
ATOM   7684  O OXT . PHE B 1 529 ? 81.021  106.249 83.419  1.00 20.41 ? 508  PHE B OXT 1 
ATOM   7685  N N   . GLY C 1 32  ? 122.925 140.678 77.175  1.00 24.51 ? 11   GLY C N   1 
ATOM   7686  C CA  . GLY C 1 32  ? 123.820 139.919 78.028  1.00 24.51 ? 11   GLY C CA  1 
ATOM   7687  C C   . GLY C 1 32  ? 123.983 140.526 79.405  1.00 24.51 ? 11   GLY C C   1 
ATOM   7688  O O   . GLY C 1 32  ? 123.123 141.273 79.869  1.00 24.51 ? 11   GLY C O   1 
ATOM   7689  N N   . VAL C 1 33  ? 125.098 140.203 80.064  1.00 25.16 ? 12   VAL C N   1 
ATOM   7690  C CA  . VAL C 1 33  ? 125.344 140.711 81.408  1.00 25.16 ? 12   VAL C CA  1 
ATOM   7691  C C   . VAL C 1 33  ? 125.659 142.201 81.411  1.00 25.16 ? 12   VAL C C   1 
ATOM   7692  O O   . VAL C 1 33  ? 125.418 142.878 82.417  1.00 25.16 ? 12   VAL C O   1 
ATOM   7693  C CB  . VAL C 1 33  ? 126.482 139.917 82.076  1.00 25.16 ? 12   VAL C CB  1 
ATOM   7694  C CG1 . VAL C 1 33  ? 126.029 138.503 82.376  1.00 25.16 ? 12   VAL C CG1 1 
ATOM   7695  C CG2 . VAL C 1 33  ? 127.712 139.897 81.184  1.00 25.16 ? 12   VAL C CG2 1 
ATOM   7696  N N   . ASN C 1 34  ? 126.184 142.734 80.307  1.00 30.95 ? 13   ASN C N   1 
ATOM   7697  C CA  . ASN C 1 34  ? 126.606 144.127 80.245  1.00 30.95 ? 13   ASN C CA  1 
ATOM   7698  C C   . ASN C 1 34  ? 125.468 145.091 79.941  1.00 30.95 ? 13   ASN C C   1 
ATOM   7699  O O   . ASN C 1 34  ? 125.658 146.304 80.070  1.00 30.95 ? 13   ASN C O   1 
ATOM   7700  C CB  . ASN C 1 34  ? 127.706 144.295 79.193  1.00 30.95 ? 13   ASN C CB  1 
ATOM   7701  C CG  . ASN C 1 34  ? 128.993 143.610 79.590  1.00 30.95 ? 13   ASN C CG  1 
ATOM   7702  O OD1 . ASN C 1 34  ? 129.154 142.408 79.389  1.00 30.95 ? 13   ASN C OD1 1 
ATOM   7703  N ND2 . ASN C 1 34  ? 129.916 144.370 80.166  1.00 30.95 ? 13   ASN C ND2 1 
ATOM   7704  N N   . ALA C 1 35  ? 124.304 144.590 79.546  1.00 26.45 ? 14   ALA C N   1 
ATOM   7705  C CA  . ALA C 1 35  ? 123.132 145.421 79.314  1.00 26.45 ? 14   ALA C CA  1 
ATOM   7706  C C   . ALA C 1 35  ? 122.297 145.445 80.585  1.00 26.45 ? 14   ALA C C   1 
ATOM   7707  O O   . ALA C 1 35  ? 121.938 144.387 81.111  1.00 26.45 ? 14   ALA C O   1 
ATOM   7708  C CB  . ALA C 1 35  ? 122.310 144.895 78.139  1.00 26.45 ? 14   ALA C CB  1 
ATOM   7709  N N   . LEU C 1 36  ? 122.006 146.648 81.080  1.00 22.82 ? 15   LEU C N   1 
ATOM   7710  C CA  . LEU C 1 36  ? 121.203 146.842 82.280  1.00 22.82 ? 15   LEU C CA  1 
ATOM   7711  C C   . LEU C 1 36  ? 119.911 146.040 82.201  1.00 22.82 ? 15   LEU C C   1 
ATOM   7712  O O   . LEU C 1 36  ? 119.022 146.368 81.406  1.00 22.82 ? 15   LEU C O   1 
ATOM   7713  C CB  . LEU C 1 36  ? 120.887 148.324 82.474  1.00 22.82 ? 15   LEU C CB  1 
ATOM   7714  C CG  . LEU C 1 36  ? 119.842 148.657 83.537  1.00 22.82 ? 15   LEU C CG  1 
ATOM   7715  C CD1 . LEU C 1 36  ? 120.462 148.682 84.922  1.00 22.82 ? 15   LEU C CD1 1 
ATOM   7716  C CD2 . LEU C 1 36  ? 119.177 149.982 83.215  1.00 22.82 ? 15   LEU C CD2 1 
ATOM   7717  N N   . PRO C 1 37  ? 119.775 144.983 83.003  1.00 20.90 ? 16   PRO C N   1 
ATOM   7718  C CA  . PRO C 1 37  ? 118.535 144.194 82.963  1.00 20.90 ? 16   PRO C CA  1 
ATOM   7719  C C   . PRO C 1 37  ? 117.328 144.974 83.429  1.00 20.90 ? 16   PRO C C   1 
ATOM   7720  O O   . PRO C 1 37  ? 116.205 144.695 82.992  1.00 20.90 ? 16   PRO C O   1 
ATOM   7721  C CB  . PRO C 1 37  ? 118.844 143.022 83.901  1.00 20.90 ? 16   PRO C CB  1 
ATOM   7722  C CG  . PRO C 1 37  ? 119.841 143.575 84.855  1.00 20.90 ? 16   PRO C CG  1 
ATOM   7723  C CD  . PRO C 1 37  ? 120.694 144.514 84.053  1.00 20.90 ? 16   PRO C CD  1 
ATOM   7724  N N   . PHE C 1 38  ? 117.535 145.951 84.301  1.00 20.88 ? 17   PHE C N   1 
ATOM   7725  C CA  . PHE C 1 38  ? 116.445 146.627 84.979  1.00 20.88 ? 17   PHE C CA  1 
ATOM   7726  C C   . PHE C 1 38  ? 115.701 147.522 83.995  1.00 20.88 ? 17   PHE C C   1 
ATOM   7727  O O   . PHE C 1 38  ? 116.266 147.987 83.003  1.00 20.88 ? 17   PHE C O   1 
ATOM   7728  C CB  . PHE C 1 38  ? 117.014 147.443 86.130  1.00 20.88 ? 17   PHE C CB  1 
ATOM   7729  C CG  . PHE C 1 38  ? 117.235 146.638 87.365  1.00 20.88 ? 17   PHE C CG  1 
ATOM   7730  C CD1 . PHE C 1 38  ? 116.204 146.364 88.236  1.00 20.88 ? 17   PHE C CD1 1 
ATOM   7731  C CD2 . PHE C 1 38  ? 118.488 146.109 87.626  1.00 20.88 ? 17   PHE C CD2 1 
ATOM   7732  C CE1 . PHE C 1 38  ? 116.430 145.602 89.358  1.00 20.88 ? 17   PHE C CE1 1 
ATOM   7733  C CE2 . PHE C 1 38  ? 118.713 145.349 88.748  1.00 20.88 ? 17   PHE C CE2 1 
ATOM   7734  C CZ  . PHE C 1 38  ? 117.678 145.096 89.619  1.00 20.88 ? 17   PHE C CZ  1 
ATOM   7735  N N   . GLU C 1 39  ? 114.418 147.766 84.260  1.00 25.78 ? 18   GLU C N   1 
ATOM   7736  C CA  . GLU C 1 39  ? 113.674 148.493 83.240  1.00 25.78 ? 18   GLU C CA  1 
ATOM   7737  C C   . GLU C 1 39  ? 113.650 149.995 83.481  1.00 25.78 ? 18   GLU C C   1 
ATOM   7738  O O   . GLU C 1 39  ? 114.295 150.735 82.740  1.00 25.78 ? 18   GLU C O   1 
ATOM   7739  C CB  . GLU C 1 39  ? 112.238 147.971 83.167  1.00 25.78 ? 18   GLU C CB  1 
ATOM   7740  C CG  . GLU C 1 39  ? 112.113 146.565 82.623  1.00 25.78 ? 18   GLU C CG  1 
ATOM   7741  C CD  . GLU C 1 39  ? 110.681 146.076 82.626  1.00 25.78 ? 18   GLU C CD  1 
ATOM   7742  O OE1 . GLU C 1 39  ? 109.816 146.779 83.190  1.00 25.78 ? 18   GLU C OE1 1 
ATOM   7743  O OE2 . GLU C 1 39  ? 110.421 144.989 82.068  1.00 25.78 ? 18   GLU C OE2 1 
ATOM   7744  N N   . GLU C 1 40  ? 112.890 150.431 84.486  1.00 25.61 ? 19   GLU C N   1 
ATOM   7745  C CA  . GLU C 1 40  ? 112.763 151.727 85.161  1.00 25.61 ? 19   GLU C CA  1 
ATOM   7746  C C   . GLU C 1 40  ? 111.588 151.627 86.119  1.00 25.61 ? 19   GLU C C   1 
ATOM   7747  O O   . GLU C 1 40  ? 110.759 150.718 86.012  1.00 25.61 ? 19   GLU C O   1 
ATOM   7748  C CB  . GLU C 1 40  ? 112.558 152.944 84.232  1.00 25.61 ? 19   GLU C CB  1 
ATOM   7749  C CG  . GLU C 1 40  ? 113.741 153.432 83.403  1.00 25.61 ? 19   GLU C CG  1 
ATOM   7750  C CD  . GLU C 1 40  ? 115.069 153.278 84.132  1.00 25.61 ? 19   GLU C CD  1 
ATOM   7751  O OE1 . GLU C 1 40  ? 115.961 152.560 83.635  1.00 25.61 ? 19   GLU C OE1 1 
ATOM   7752  O OE2 . GLU C 1 40  ? 115.221 153.889 85.212  1.00 25.61 ? 19   GLU C OE2 1 
ATOM   7753  N N   . ARG C 1 41  ? 111.535 152.569 87.061  1.00 24.50 ? 20   ARG C N   1 
ATOM   7754  C CA  . ARG C 1 41  ? 110.311 152.940 87.762  1.00 24.50 ? 20   ARG C CA  1 
ATOM   7755  C C   . ARG C 1 41  ? 109.483 151.752 88.237  1.00 24.50 ? 20   ARG C C   1 
ATOM   7756  O O   . ARG C 1 41  ? 108.251 151.794 88.174  1.00 24.50 ? 20   ARG C O   1 
ATOM   7757  C CB  . ARG C 1 41  ? 109.462 153.818 86.842  1.00 24.50 ? 20   ARG C CB  1 
ATOM   7758  C CG  . ARG C 1 41  ? 110.094 155.166 86.521  1.00 24.50 ? 20   ARG C CG  1 
ATOM   7759  C CD  . ARG C 1 41  ? 109.540 156.300 87.367  1.00 24.50 ? 20   ARG C CD  1 
ATOM   7760  N NE  . ARG C 1 41  ? 108.100 156.179 87.562  1.00 24.50 ? 20   ARG C NE  1 
ATOM   7761  C CZ  . ARG C 1 41  ? 107.393 156.929 88.399  1.00 24.50 ? 20   ARG C CZ  1 
ATOM   7762  N NH1 . ARG C 1 41  ? 107.992 157.866 89.120  1.00 24.50 ? 20   ARG C NH1 1 
ATOM   7763  N NH2 . ARG C 1 41  ? 106.084 156.748 88.509  1.00 24.50 ? 20   ARG C NH2 1 
ATOM   7764  N N   . TYR C 1 42  ? 110.139 150.684 88.687  1.00 20.10 ? 21   TYR C N   1 
ATOM   7765  C CA  . TYR C 1 42  ? 109.432 149.564 89.296  1.00 20.10 ? 21   TYR C CA  1 
ATOM   7766  C C   . TYR C 1 42  ? 108.527 150.032 90.424  1.00 20.10 ? 21   TYR C C   1 
ATOM   7767  O O   . TYR C 1 42  ? 108.979 150.664 91.381  1.00 20.10 ? 21   TYR C O   1 
ATOM   7768  C CB  . TYR C 1 42  ? 110.433 148.534 89.823  1.00 20.10 ? 21   TYR C CB  1 
ATOM   7769  C CG  . TYR C 1 42  ? 110.952 147.560 88.795  1.00 20.10 ? 21   TYR C CG  1 
ATOM   7770  C CD1 . TYR C 1 42  ? 110.209 147.248 87.671  1.00 20.10 ? 21   TYR C CD1 1 
ATOM   7771  C CD2 . TYR C 1 42  ? 112.201 146.983 88.932  1.00 20.10 ? 21   TYR C CD2 1 
ATOM   7772  C CE1 . TYR C 1 42  ? 110.681 146.357 86.733  1.00 20.10 ? 21   TYR C CE1 1 
ATOM   7773  C CE2 . TYR C 1 42  ? 112.685 146.100 87.993  1.00 20.10 ? 21   TYR C CE2 1 
ATOM   7774  C CZ  . TYR C 1 42  ? 111.922 145.790 86.897  1.00 20.10 ? 21   TYR C CZ  1 
ATOM   7775  O OH  . TYR C 1 42  ? 112.398 144.908 85.958  1.00 20.10 ? 21   TYR C OH  1 
ATOM   7776  N N   . ASP C 1 43  ? 107.247 149.722 90.301  1.00 16.22 ? 22   ASP C N   1 
ATOM   7777  C CA  . ASP C 1 43  ? 106.275 149.944 91.354  1.00 16.22 ? 22   ASP C CA  1 
ATOM   7778  C C   . ASP C 1 43  ? 106.006 148.620 92.055  1.00 16.22 ? 22   ASP C C   1 
ATOM   7779  O O   . ASP C 1 43  ? 106.663 147.608 91.790  1.00 16.22 ? 22   ASP C O   1 
ATOM   7780  C CB  . ASP C 1 43  ? 104.999 150.554 90.781  1.00 16.22 ? 22   ASP C CB  1 
ATOM   7781  C CG  . ASP C 1 43  ? 104.451 149.759 89.622  1.00 16.22 ? 22   ASP C CG  1 
ATOM   7782  O OD1 . ASP C 1 43  ? 105.230 149.007 89.000  1.00 16.22 ? 22   ASP C OD1 1 
ATOM   7783  O OD2 . ASP C 1 43  ? 103.242 149.880 89.336  1.00 16.22 ? 22   ASP C OD2 1 
ATOM   7784  N N   . ASN C 1 44  ? 105.033 148.625 92.958  1.00 13.70 ? 23   ASN C N   1 
ATOM   7785  C CA  . ASN C 1 44  ? 104.669 147.415 93.671  1.00 13.70 ? 23   ASN C CA  1 
ATOM   7786  C C   . ASN C 1 44  ? 104.006 146.418 92.720  1.00 13.70 ? 23   ASN C C   1 
ATOM   7787  O O   . ASN C 1 44  ? 103.758 146.699 91.546  1.00 13.70 ? 23   ASN C O   1 
ATOM   7788  C CB  . ASN C 1 44  ? 103.759 147.759 94.841  1.00 13.70 ? 23   ASN C CB  1 
ATOM   7789  C CG  . ASN C 1 44  ? 104.405 148.720 95.799  1.00 13.70 ? 23   ASN C CG  1 
ATOM   7790  O OD1 . ASN C 1 44  ? 105.407 148.401 96.431  1.00 13.70 ? 23   ASN C OD1 1 
ATOM   7791  N ND2 . ASN C 1 44  ? 103.849 149.917 95.900  1.00 13.70 ? 23   ASN C ND2 1 
ATOM   7792  N N   . PHE C 1 45  ? 103.714 145.230 93.243  1.00 10.04 ? 24   PHE C N   1 
ATOM   7793  C CA  . PHE C 1 45  ? 103.076 144.156 92.479  1.00 10.04 ? 24   PHE C CA  1 
ATOM   7794  C C   . PHE C 1 45  ? 102.055 143.508 93.411  1.00 10.04 ? 24   PHE C C   1 
ATOM   7795  O O   . PHE C 1 45  ? 102.393 142.633 94.208  1.00 10.04 ? 24   PHE C O   1 
ATOM   7796  C CB  . PHE C 1 45  ? 104.103 143.157 91.970  1.00 10.04 ? 24   PHE C CB  1 
ATOM   7797  C CG  . PHE C 1 45  ? 103.513 142.012 91.213  1.00 10.04 ? 24   PHE C CG  1 
ATOM   7798  C CD1 . PHE C 1 45  ? 103.127 142.165 89.897  1.00 10.04 ? 24   PHE C CD1 1 
ATOM   7799  C CD2 . PHE C 1 45  ? 103.351 140.781 91.810  1.00 10.04 ? 24   PHE C CD2 1 
ATOM   7800  C CE1 . PHE C 1 45  ? 102.588 141.113 89.196  1.00 10.04 ? 24   PHE C CE1 1 
ATOM   7801  C CE2 . PHE C 1 45  ? 102.812 139.725 91.111  1.00 10.04 ? 24   PHE C CE2 1 
ATOM   7802  C CZ  . PHE C 1 45  ? 102.430 139.892 89.804  1.00 10.04 ? 24   PHE C CZ  1 
ATOM   7803  N N   . ILE C 1 46  ? 100.807 143.954 93.315  1.00 9.85  ? 25   ILE C N   1 
ATOM   7804  C CA  . ILE C 1 46  ? 99.753  143.540 94.230  1.00 9.85  ? 25   ILE C CA  1 
ATOM   7805  C C   . ILE C 1 46  ? 98.571  143.053 93.414  1.00 9.85  ? 25   ILE C C   1 
ATOM   7806  O O   . ILE C 1 46  ? 98.052  143.792 92.571  1.00 9.85  ? 25   ILE C O   1 
ATOM   7807  C CB  . ILE C 1 46  ? 99.319  144.681 95.158  1.00 9.85  ? 25   ILE C CB  1 
ATOM   7808  C CG1 . ILE C 1 46  ? 100.499 145.160 96.000  1.00 9.85  ? 25   ILE C CG1 1 
ATOM   7809  C CG2 . ILE C 1 46  ? 98.168  144.232 96.031  1.00 9.85  ? 25   ILE C CG2 1 
ATOM   7810  C CD1 . ILE C 1 46  ? 100.429 146.614 96.338  1.00 9.85  ? 25   ILE C CD1 1 
ATOM   7811  N N   . GLY C 1 47  ? 98.144  141.818 93.663  1.00 8.90  ? 26   GLY C N   1 
ATOM   7812  C CA  . GLY C 1 47  ? 96.989  141.279 92.979  1.00 8.90  ? 26   GLY C CA  1 
ATOM   7813  C C   . GLY C 1 47  ? 97.211  140.946 91.526  1.00 8.90  ? 26   GLY C C   1 
ATOM   7814  O O   . GLY C 1 47  ? 96.245  140.864 90.766  1.00 8.90  ? 26   GLY C O   1 
ATOM   7815  N N   . GLY C 1 48  ? 98.456  140.762 91.108  1.00 9.80  ? 27   GLY C N   1 
ATOM   7816  C CA  . GLY C 1 48  ? 98.749  140.426 89.738  1.00 9.80  ? 27   GLY C CA  1 
ATOM   7817  C C   . GLY C 1 48  ? 98.973  141.605 88.820  1.00 9.80  ? 27   GLY C C   1 
ATOM   7818  O O   . GLY C 1 48  ? 99.435  141.406 87.688  1.00 9.80  ? 27   GLY C O   1 
ATOM   7819  N N   . GLU C 1 49  ? 98.670  142.824 89.264  1.00 11.75 ? 28   GLU C N   1 
ATOM   7820  C CA  . GLU C 1 49  ? 98.906  144.020 88.472  1.00 11.75 ? 28   GLU C CA  1 
ATOM   7821  C C   . GLU C 1 49  ? 99.891  144.929 89.194  1.00 11.75 ? 28   GLU C C   1 
ATOM   7822  O O   . GLU C 1 49  ? 99.947  144.958 90.426  1.00 11.75 ? 28   GLU C O   1 
ATOM   7823  C CB  . GLU C 1 49  ? 97.605  144.784 88.185  1.00 11.75 ? 28   GLU C CB  1 
ATOM   7824  C CG  . GLU C 1 49  ? 96.988  145.501 89.382  1.00 11.75 ? 28   GLU C CG  1 
ATOM   7825  C CD  . GLU C 1 49  ? 96.112  144.606 90.231  1.00 11.75 ? 28   GLU C CD  1 
ATOM   7826  O OE1 . GLU C 1 49  ? 95.873  144.949 91.407  1.00 11.75 ? 28   GLU C OE1 1 
ATOM   7827  O OE2 . GLU C 1 49  ? 95.655  143.563 89.724  1.00 11.75 ? 28   GLU C OE2 1 
ATOM   7828  N N   . TRP C 1 50  ? 100.672 145.668 88.409  1.00 11.12 ? 29   TRP C N   1 
ATOM   7829  C CA  . TRP C 1 50  ? 101.668 146.604 88.926  1.00 11.12 ? 29   TRP C CA  1 
ATOM   7830  C C   . TRP C 1 50  ? 100.947 147.812 89.504  1.00 11.12 ? 29   TRP C C   1 
ATOM   7831  O O   . TRP C 1 50  ? 100.487 148.694 88.780  1.00 11.12 ? 29   TRP C O   1 
ATOM   7832  C CB  . TRP C 1 50  ? 102.633 147.018 87.826  1.00 11.12 ? 29   TRP C CB  1 
ATOM   7833  C CG  . TRP C 1 50  ? 103.445 145.895 87.288  1.00 11.12 ? 29   TRP C CG  1 
ATOM   7834  C CD1 . TRP C 1 50  ? 103.275 145.261 86.096  1.00 11.12 ? 29   TRP C CD1 1 
ATOM   7835  C CD2 . TRP C 1 50  ? 104.560 145.267 87.924  1.00 11.12 ? 29   TRP C CD2 1 
ATOM   7836  N NE1 . TRP C 1 50  ? 104.217 144.273 85.949  1.00 11.12 ? 29   TRP C NE1 1 
ATOM   7837  C CE2 . TRP C 1 50  ? 105.018 144.258 87.059  1.00 11.12 ? 29   TRP C CE2 1 
ATOM   7838  C CE3 . TRP C 1 50  ? 105.215 145.460 89.142  1.00 11.12 ? 29   TRP C CE3 1 
ATOM   7839  C CZ2 . TRP C 1 50  ? 106.099 143.445 87.373  1.00 11.12 ? 29   TRP C CZ2 1 
ATOM   7840  C CZ3 . TRP C 1 50  ? 106.285 144.654 89.450  1.00 11.12 ? 29   TRP C CZ3 1 
ATOM   7841  C CH2 . TRP C 1 50  ? 106.719 143.659 88.571  1.00 11.12 ? 29   TRP C CH2 1 
ATOM   7842  N N   . VAL C 1 51  ? 100.853 147.860 90.827  1.00 12.99 ? 30   VAL C N   1 
ATOM   7843  C CA  . VAL C 1 51  ? 100.173 148.955 91.507  1.00 12.99 ? 30   VAL C CA  1 
ATOM   7844  C C   . VAL C 1 51  ? 101.193 150.012 91.912  1.00 12.99 ? 30   VAL C C   1 
ATOM   7845  O O   . VAL C 1 51  ? 102.188 149.711 92.580  1.00 12.99 ? 30   VAL C O   1 
ATOM   7846  C CB  . VAL C 1 51  ? 99.400  148.438 92.729  1.00 12.99 ? 30   VAL C CB  1 
ATOM   7847  C CG1 . VAL C 1 51  ? 98.783  149.591 93.492  1.00 12.99 ? 30   VAL C CG1 1 
ATOM   7848  C CG2 . VAL C 1 51  ? 98.335  147.457 92.296  1.00 12.99 ? 30   VAL C CG2 1 
ATOM   7849  N N   . ALA C 1 52  ? 100.944 151.255 91.510  1.00 16.37 ? 31   ALA C N   1 
ATOM   7850  C CA  . ALA C 1 52  ? 101.796 152.362 91.898  1.00 16.37 ? 31   ALA C CA  1 
ATOM   7851  C C   . ALA C 1 52  ? 101.598 152.690 93.377  1.00 16.37 ? 31   ALA C C   1 
ATOM   7852  O O   . ALA C 1 52  ? 100.573 152.341 93.966  1.00 16.37 ? 31   ALA C O   1 
ATOM   7853  C CB  . ALA C 1 52  ? 101.492 153.585 91.039  1.00 16.37 ? 31   ALA C CB  1 
ATOM   7854  N N   . PRO C 1 53  ? 102.573 153.352 94.002  1.00 20.67 ? 32   PRO C N   1 
ATOM   7855  C CA  . PRO C 1 53  ? 102.425 153.714 95.418  1.00 20.67 ? 32   PRO C CA  1 
ATOM   7856  C C   . PRO C 1 53  ? 101.209 154.595 95.658  1.00 20.67 ? 32   PRO C C   1 
ATOM   7857  O O   . PRO C 1 53  ? 100.855 155.439 94.832  1.00 20.67 ? 32   PRO C O   1 
ATOM   7858  C CB  . PRO C 1 53  ? 103.721 154.467 95.727  1.00 20.67 ? 32   PRO C CB  1 
ATOM   7859  C CG  . PRO C 1 53  ? 104.691 153.961 94.739  1.00 20.67 ? 32   PRO C CG  1 
ATOM   7860  C CD  . PRO C 1 53  ? 103.927 153.632 93.498  1.00 20.67 ? 32   PRO C CD  1 
ATOM   7861  N N   . VAL C 1 54  ? 100.568 154.388 96.811  1.00 25.20 ? 33   VAL C N   1 
ATOM   7862  C CA  . VAL C 1 54  ? 99.449  155.240 97.208  1.00 25.20 ? 33   VAL C CA  1 
ATOM   7863  C C   . VAL C 1 54  ? 99.911  156.683 97.385  1.00 25.20 ? 33   VAL C C   1 
ATOM   7864  O O   . VAL C 1 54  ? 99.224  157.625 96.975  1.00 25.20 ? 33   VAL C O   1 
ATOM   7865  C CB  . VAL C 1 54  ? 98.773  154.683 98.477  1.00 25.20 ? 33   VAL C CB  1 
ATOM   7866  C CG1 . VAL C 1 54  ? 99.729  154.675 99.661  1.00 25.20 ? 33   VAL C CG1 1 
ATOM   7867  C CG2 . VAL C 1 54  ? 97.524  155.487 98.806  1.00 25.20 ? 33   VAL C CG2 1 
ATOM   7868  N N   . SER C 1 55  ? 101.076 156.878 97.992  1.00 24.32 ? 34   SER C N   1 
ATOM   7869  C CA  . SER C 1 55  ? 101.721 158.183 98.091  1.00 24.32 ? 34   SER C CA  1 
ATOM   7870  C C   . SER C 1 55  ? 102.940 158.132 97.180  1.00 24.32 ? 34   SER C C   1 
ATOM   7871  O O   . SER C 1 55  ? 103.946 157.501 97.516  1.00 24.32 ? 34   SER C O   1 
ATOM   7872  C CB  . SER C 1 55  ? 102.106 158.500 99.530  1.00 24.32 ? 34   SER C CB  1 
ATOM   7873  O OG  . SER C 1 55  ? 103.204 157.709 99.946  1.00 24.32 ? 34   SER C OG  1 
ATOM   7874  N N   . GLY C 1 56  ? 102.842 158.786 96.025  1.00 22.97 ? 35   GLY C N   1 
ATOM   7875  C CA  . GLY C 1 56  ? 103.879 158.721 95.013  1.00 22.97 ? 35   GLY C CA  1 
ATOM   7876  C C   . GLY C 1 56  ? 105.276 159.001 95.525  1.00 22.97 ? 35   GLY C C   1 
ATOM   7877  O O   . GLY C 1 56  ? 105.563 160.107 95.992  1.00 22.97 ? 35   GLY C O   1 
ATOM   7878  N N   . ARG C 1 57  ? 106.149 157.998 95.445  1.00 25.72 ? 36   ARG C N   1 
ATOM   7879  C CA  . ARG C 1 57  ? 107.536 158.124 95.871  1.00 25.72 ? 36   ARG C CA  1 
ATOM   7880  C C   . ARG C 1 57  ? 108.351 157.019 95.221  1.00 25.72 ? 36   ARG C C   1 
ATOM   7881  O O   . ARG C 1 57  ? 107.855 155.914 94.995  1.00 25.72 ? 36   ARG C O   1 
ATOM   7882  C CB  . ARG C 1 57  ? 107.673 158.060 97.394  1.00 25.72 ? 36   ARG C CB  1 
ATOM   7883  C CG  . ARG C 1 57  ? 107.823 159.418 98.050  1.00 25.72 ? 36   ARG C CG  1 
ATOM   7884  C CD  . ARG C 1 57  ? 107.438 159.378 99.521  1.00 25.72 ? 36   ARG C CD  1 
ATOM   7885  N NE  . ARG C 1 57  ? 108.428 158.690 100.349 1.00 25.72 ? 36   ARG C NE  1 
ATOM   7886  C CZ  . ARG C 1 57  ? 109.677 159.106 100.547 1.00 25.72 ? 36   ARG C CZ  1 
ATOM   7887  N NH1 . ARG C 1 57  ? 110.117 160.223 99.983  1.00 25.72 ? 36   ARG C NH1 1 
ATOM   7888  N NH2 . ARG C 1 57  ? 110.491 158.402 101.323 1.00 25.72 ? 36   ARG C NH2 1 
ATOM   7889  N N   . TYR C 1 58  ? 109.611 157.331 94.931  1.00 23.16 ? 37   TYR C N   1 
ATOM   7890  C CA  . TYR C 1 58  ? 110.493 156.409 94.223  1.00 23.16 ? 37   TYR C CA  1 
ATOM   7891  C C   . TYR C 1 58  ? 111.914 156.637 94.716  1.00 23.16 ? 37   TYR C C   1 
ATOM   7892  O O   . TYR C 1 58  ? 112.520 157.662 94.395  1.00 23.16 ? 37   TYR C O   1 
ATOM   7893  C CB  . TYR C 1 58  ? 110.404 156.618 92.713  1.00 23.16 ? 37   TYR C CB  1 
ATOM   7894  C CG  . TYR C 1 58  ? 109.203 155.975 92.063  1.00 23.16 ? 37   TYR C CG  1 
ATOM   7895  C CD1 . TYR C 1 58  ? 107.961 156.594 92.080  1.00 23.16 ? 37   TYR C CD1 1 
ATOM   7896  C CD2 . TYR C 1 58  ? 109.316 154.754 91.414  1.00 23.16 ? 37   TYR C CD2 1 
ATOM   7897  C CE1 . TYR C 1 58  ? 106.864 156.006 91.494  1.00 23.16 ? 37   TYR C CE1 1 
ATOM   7898  C CE2 . TYR C 1 58  ? 108.226 154.162 90.815  1.00 23.16 ? 37   TYR C CE2 1 
ATOM   7899  C CZ  . TYR C 1 58  ? 107.003 154.793 90.857  1.00 23.16 ? 37   TYR C CZ  1 
ATOM   7900  O OH  . TYR C 1 58  ? 105.914 154.205 90.260  1.00 23.16 ? 37   TYR C OH  1 
ATOM   7901  N N   . PHE C 1 59  ? 112.446 155.692 95.484  1.00 20.36 ? 38   PHE C N   1 
ATOM   7902  C CA  . PHE C 1 59  ? 113.839 155.779 95.894  1.00 20.36 ? 38   PHE C CA  1 
ATOM   7903  C C   . PHE C 1 59  ? 114.722 155.146 94.827  1.00 20.36 ? 38   PHE C C   1 
ATOM   7904  O O   . PHE C 1 59  ? 114.307 154.236 94.109  1.00 20.36 ? 38   PHE C O   1 
ATOM   7905  C CB  . PHE C 1 59  ? 114.066 155.132 97.269  1.00 20.36 ? 38   PHE C CB  1 
ATOM   7906  C CG  . PHE C 1 59  ? 114.152 153.627 97.255  1.00 20.36 ? 38   PHE C CG  1 
ATOM   7907  C CD1 . PHE C 1 59  ? 115.342 152.982 96.959  1.00 20.36 ? 38   PHE C CD1 1 
ATOM   7908  C CD2 . PHE C 1 59  ? 113.053 152.858 97.584  1.00 20.36 ? 38   PHE C CD2 1 
ATOM   7909  C CE1 . PHE C 1 59  ? 115.419 151.607 96.958  1.00 20.36 ? 38   PHE C CE1 1 
ATOM   7910  C CE2 . PHE C 1 59  ? 113.128 151.485 97.587  1.00 20.36 ? 38   PHE C CE2 1 
ATOM   7911  C CZ  . PHE C 1 59  ? 114.311 150.860 97.274  1.00 20.36 ? 38   PHE C CZ  1 
ATOM   7912  N N   . THR C 1 60  ? 115.944 155.651 94.714  1.00 20.43 ? 39   THR C N   1 
ATOM   7913  C CA  . THR C 1 60  ? 116.799 155.243 93.611  1.00 20.43 ? 39   THR C CA  1 
ATOM   7914  C C   . THR C 1 60  ? 117.440 153.887 93.885  1.00 20.43 ? 39   THR C C   1 
ATOM   7915  O O   . THR C 1 60  ? 117.665 153.495 95.034  1.00 20.43 ? 39   THR C O   1 
ATOM   7916  C CB  . THR C 1 60  ? 117.875 156.296 93.338  1.00 20.43 ? 39   THR C CB  1 
ATOM   7917  O OG1 . THR C 1 60  ? 118.469 156.044 92.061  1.00 20.43 ? 39   THR C OG1 1 
ATOM   7918  C CG2 . THR C 1 60  ? 118.955 156.265 94.404  1.00 20.43 ? 39   THR C CG2 1 
ATOM   7919  N N   . ASN C 1 61  ? 117.715 153.162 92.807  1.00 18.47 ? 40   ASN C N   1 
ATOM   7920  C CA  . ASN C 1 61  ? 118.357 151.855 92.864  1.00 18.47 ? 40   ASN C CA  1 
ATOM   7921  C C   . ASN C 1 61  ? 119.838 152.088 92.614  1.00 18.47 ? 40   ASN C C   1 
ATOM   7922  O O   . ASN C 1 61  ? 120.253 152.346 91.483  1.00 18.47 ? 40   ASN C O   1 
ATOM   7923  C CB  . ASN C 1 61  ? 117.749 150.913 91.829  1.00 18.47 ? 40   ASN C CB  1 
ATOM   7924  C CG  . ASN C 1 61  ? 118.092 149.453 92.076  1.00 18.47 ? 40   ASN C CG  1 
ATOM   7925  O OD1 . ASN C 1 61  ? 118.764 149.108 93.045  1.00 18.47 ? 40   ASN C OD1 1 
ATOM   7926  N ND2 . ASN C 1 61  ? 117.620 148.587 91.193  1.00 18.47 ? 40   ASN C ND2 1 
ATOM   7927  N N   . THR C 1 62  ? 120.635 152.013 93.674  1.00 18.53 ? 41   THR C N   1 
ATOM   7928  C CA  . THR C 1 62  ? 122.075 152.221 93.589  1.00 18.53 ? 41   THR C CA  1 
ATOM   7929  C C   . THR C 1 62  ? 122.745 150.857 93.491  1.00 18.53 ? 41   THR C C   1 
ATOM   7930  O O   . THR C 1 62  ? 122.789 150.111 94.475  1.00 18.53 ? 41   THR C O   1 
ATOM   7931  C CB  . THR C 1 62  ? 122.585 152.998 94.802  1.00 18.53 ? 41   THR C CB  1 
ATOM   7932  O OG1 . THR C 1 62  ? 121.865 154.231 94.921  1.00 18.53 ? 41   THR C OG1 1 
ATOM   7933  C CG2 . THR C 1 62  ? 124.069 153.301 94.656  1.00 18.53 ? 41   THR C CG2 1 
ATOM   7934  N N   . THR C 1 63  ? 123.258 150.526 92.312  1.00 17.63 ? 42   THR C N   1 
ATOM   7935  C CA  . THR C 1 63  ? 123.926 149.243 92.146  1.00 17.63 ? 42   THR C CA  1 
ATOM   7936  C C   . THR C 1 63  ? 125.237 149.242 92.928  1.00 17.63 ? 42   THR C C   1 
ATOM   7937  O O   . THR C 1 63  ? 126.038 150.171 92.792  1.00 17.63 ? 42   THR C O   1 
ATOM   7938  C CB  . THR C 1 63  ? 124.167 148.929 90.667  1.00 17.63 ? 42   THR C CB  1 
ATOM   7939  O OG1 . THR C 1 63  ? 124.816 147.659 90.546  1.00 17.63 ? 42   THR C OG1 1 
ATOM   7940  C CG2 . THR C 1 63  ? 125.015 149.985 89.992  1.00 17.63 ? 42   THR C CG2 1 
ATOM   7941  N N   . PRO C 1 64  ? 125.468 148.253 93.795  1.00 17.57 ? 43   PRO C N   1 
ATOM   7942  C CA  . PRO C 1 64  ? 126.743 148.203 94.523  1.00 17.57 ? 43   PRO C CA  1 
ATOM   7943  C C   . PRO C 1 64  ? 127.951 148.003 93.628  1.00 17.57 ? 43   PRO C C   1 
ATOM   7944  O O   . PRO C 1 64  ? 129.069 148.292 94.066  1.00 17.57 ? 43   PRO C O   1 
ATOM   7945  C CB  . PRO C 1 64  ? 126.556 147.017 95.475  1.00 17.57 ? 43   PRO C CB  1 
ATOM   7946  C CG  . PRO C 1 64  ? 125.087 146.891 95.625  1.00 17.57 ? 43   PRO C CG  1 
ATOM   7947  C CD  . PRO C 1 64  ? 124.497 147.278 94.315  1.00 17.57 ? 43   PRO C CD  1 
ATOM   7948  N N   . ILE C 1 65  ? 127.766 147.524 92.396  1.00 18.18 ? 44   ILE C N   1 
ATOM   7949  C CA  . ILE C 1 65  ? 128.901 147.280 91.509  1.00 18.18 ? 44   ILE C CA  1 
ATOM   7950  C C   . ILE C 1 65  ? 129.649 148.573 91.224  1.00 18.18 ? 44   ILE C C   1 
ATOM   7951  O O   . ILE C 1 65  ? 130.885 148.610 91.244  1.00 18.18 ? 44   ILE C O   1 
ATOM   7952  C CB  . ILE C 1 65  ? 128.428 146.615 90.204  1.00 18.18 ? 44   ILE C CB  1 
ATOM   7953  C CG1 . ILE C 1 65  ? 127.732 145.289 90.493  1.00 18.18 ? 44   ILE C CG1 1 
ATOM   7954  C CG2 . ILE C 1 65  ? 129.599 146.406 89.260  1.00 18.18 ? 44   ILE C CG2 1 
ATOM   7955  C CD1 . ILE C 1 65  ? 127.337 144.543 89.246  1.00 18.18 ? 44   ILE C CD1 1 
ATOM   7956  N N   . THR C 1 66  ? 128.916 149.650 90.939  1.00 17.79 ? 45   THR C N   1 
ATOM   7957  C CA  . THR C 1 66  ? 129.520 150.932 90.606  1.00 17.79 ? 45   THR C CA  1 
ATOM   7958  C C   . THR C 1 66  ? 128.929 152.110 91.362  1.00 17.79 ? 45   THR C C   1 
ATOM   7959  O O   . THR C 1 66  ? 129.476 153.212 91.261  1.00 17.79 ? 45   THR C O   1 
ATOM   7960  C CB  . THR C 1 66  ? 129.397 151.219 89.101  1.00 17.79 ? 45   THR C CB  1 
ATOM   7961  O OG1 . THR C 1 66  ? 128.023 151.439 88.768  1.00 17.79 ? 45   THR C OG1 1 
ATOM   7962  C CG2 . THR C 1 66  ? 129.940 150.062 88.274  1.00 17.79 ? 45   THR C CG2 1 
ATOM   7963  N N   . GLY C 1 67  ? 127.849 151.924 92.112  1.00 17.89 ? 46   GLY C N   1 
ATOM   7964  C CA  . GLY C 1 67  ? 127.198 153.052 92.748  1.00 17.89 ? 46   GLY C CA  1 
ATOM   7965  C C   . GLY C 1 67  ? 126.446 153.941 91.787  1.00 17.89 ? 46   GLY C C   1 
ATOM   7966  O O   . GLY C 1 67  ? 126.225 155.118 92.083  1.00 17.89 ? 46   GLY C O   1 
ATOM   7967  N N   . ALA C 1 68  ? 126.044 153.407 90.638  1.00 18.18 ? 47   ALA C N   1 
ATOM   7968  C CA  . ALA C 1 68  ? 125.332 154.158 89.615  1.00 18.18 ? 47   ALA C CA  1 
ATOM   7969  C C   . ALA C 1 68  ? 123.844 153.856 89.710  1.00 18.18 ? 47   ALA C C   1 
ATOM   7970  O O   . ALA C 1 68  ? 123.450 152.692 89.804  1.00 18.18 ? 47   ALA C O   1 
ATOM   7971  C CB  . ALA C 1 68  ? 125.855 153.814 88.221  1.00 18.18 ? 47   ALA C CB  1 
ATOM   7972  N N   . GLU C 1 69  ? 123.025 154.904 89.696  1.00 19.18 ? 48   GLU C N   1 
ATOM   7973  C CA  . GLU C 1 69  ? 121.582 154.725 89.781  1.00 19.18 ? 48   GLU C CA  1 
ATOM   7974  C C   . GLU C 1 69  ? 121.076 153.947 88.575  1.00 19.18 ? 48   GLU C C   1 
ATOM   7975  O O   . GLU C 1 69  ? 121.371 154.294 87.429  1.00 19.18 ? 48   GLU C O   1 
ATOM   7976  C CB  . GLU C 1 69  ? 120.892 156.085 89.872  1.00 19.18 ? 48   GLU C CB  1 
ATOM   7977  C CG  . GLU C 1 69  ? 121.335 156.925 91.065  1.00 19.18 ? 48   GLU C CG  1 
ATOM   7978  C CD  . GLU C 1 69  ? 122.583 157.742 90.783  1.00 19.18 ? 48   GLU C CD  1 
ATOM   7979  O OE1 . GLU C 1 69  ? 122.798 158.114 89.611  1.00 19.18 ? 48   GLU C OE1 1 
ATOM   7980  O OE2 . GLU C 1 69  ? 123.349 158.007 91.733  1.00 19.18 ? 48   GLU C OE2 1 
ATOM   7981  N N   . ILE C 1 70  ? 120.300 152.893 88.837  1.00 19.64 ? 49   ILE C N   1 
ATOM   7982  C CA  . ILE C 1 70  ? 119.884 151.956 87.801  1.00 19.64 ? 49   ILE C CA  1 
ATOM   7983  C C   . ILE C 1 70  ? 118.377 151.756 87.741  1.00 19.64 ? 49   ILE C C   1 
ATOM   7984  O O   . ILE C 1 70  ? 117.903 150.987 86.902  1.00 19.64 ? 49   ILE C O   1 
ATOM   7985  C CB  . ILE C 1 70  ? 120.596 150.597 87.965  1.00 19.64 ? 49   ILE C CB  1 
ATOM   7986  C CG1 . ILE C 1 70  ? 120.383 150.044 89.375  1.00 19.64 ? 49   ILE C CG1 1 
ATOM   7987  C CG2 . ILE C 1 70  ? 122.076 150.724 87.630  1.00 19.64 ? 49   ILE C CG2 1 
ATOM   7988  C CD1 . ILE C 1 70  ? 120.390 148.544 89.450  1.00 19.64 ? 49   ILE C CD1 1 
ATOM   7989  N N   . GLY C 1 71  ? 117.606 152.417 88.595  1.00 20.36 ? 50   GLY C N   1 
ATOM   7990  C CA  . GLY C 1 71  ? 116.161 152.310 88.520  1.00 20.36 ? 50   GLY C CA  1 
ATOM   7991  C C   . GLY C 1 71  ? 115.518 153.121 89.619  1.00 20.36 ? 50   GLY C C   1 
ATOM   7992  O O   . GLY C 1 71  ? 116.195 153.724 90.454  1.00 20.36 ? 50   GLY C O   1 
ATOM   7993  N N   . GLN C 1 72  ? 114.188 153.121 89.614  1.00 21.36 ? 51   GLN C N   1 
ATOM   7994  C CA  . GLN C 1 72  ? 113.399 153.786 90.644  1.00 21.36 ? 51   GLN C CA  1 
ATOM   7995  C C   . GLN C 1 72  ? 112.451 152.767 91.250  1.00 21.36 ? 51   GLN C C   1 
ATOM   7996  O O   . GLN C 1 72  ? 111.792 152.022 90.520  1.00 21.36 ? 51   GLN C O   1 
ATOM   7997  C CB  . GLN C 1 72  ? 112.619 154.974 90.073  1.00 21.36 ? 51   GLN C CB  1 
ATOM   7998  C CG  . GLN C 1 72  ? 113.486 156.006 89.374  1.00 21.36 ? 51   GLN C CG  1 
ATOM   7999  C CD  . GLN C 1 72  ? 113.706 157.242 90.219  1.00 21.36 ? 51   GLN C CD  1 
ATOM   8000  O OE1 . GLN C 1 72  ? 112.754 157.906 90.626  1.00 21.36 ? 51   GLN C OE1 1 
ATOM   8001  N NE2 . GLN C 1 72  ? 114.967 157.555 90.496  1.00 21.36 ? 51   GLN C NE2 1 
ATOM   8002  N N   . ILE C 1 73  ? 112.379 152.731 92.576  1.00 19.87 ? 52   ILE C N   1 
ATOM   8003  C CA  . ILE C 1 73  ? 111.670 151.683 93.293  1.00 19.87 ? 52   ILE C CA  1 
ATOM   8004  C C   . ILE C 1 73  ? 110.609 152.319 94.175  1.00 19.87 ? 52   ILE C C   1 
ATOM   8005  O O   . ILE C 1 73  ? 110.871 153.316 94.855  1.00 19.87 ? 52   ILE C O   1 
ATOM   8006  C CB  . ILE C 1 73  ? 112.636 150.825 94.134  1.00 19.87 ? 52   ILE C CB  1 
ATOM   8007  C CG1 . ILE C 1 73  ? 113.779 150.303 93.265  1.00 19.87 ? 52   ILE C CG1 1 
ATOM   8008  C CG2 . ILE C 1 73  ? 111.899 149.677 94.781  1.00 19.87 ? 52   ILE C CG2 1 
ATOM   8009  C CD1 . ILE C 1 73  ? 113.319 149.547 92.051  1.00 19.87 ? 52   ILE C CD1 1 
ATOM   8010  N N   . ALA C 1 74  ? 109.417 151.731 94.165  1.00 20.15 ? 53   ALA C N   1 
ATOM   8011  C CA  . ALA C 1 74  ? 108.299 152.255 94.933  1.00 20.15 ? 53   ALA C CA  1 
ATOM   8012  C C   . ALA C 1 74  ? 108.620 152.297 96.421  1.00 20.15 ? 53   ALA C C   1 
ATOM   8013  O O   . ALA C 1 74  ? 109.276 151.402 96.958  1.00 20.15 ? 53   ALA C O   1 
ATOM   8014  C CB  . ALA C 1 74  ? 107.061 151.396 94.693  1.00 20.15 ? 53   ALA C CB  1 
ATOM   8015  N N   . ARG C 1 75  ? 108.151 153.346 97.086  1.00 25.49 ? 54   ARG C N   1 
ATOM   8016  C CA  . ARG C 1 75  ? 108.359 153.547 98.519  1.00 25.49 ? 54   ARG C CA  1 
ATOM   8017  C C   . ARG C 1 75  ? 107.006 153.452 99.220  1.00 25.49 ? 54   ARG C C   1 
ATOM   8018  O O   . ARG C 1 75  ? 106.328 154.457 99.430  1.00 25.49 ? 54   ARG C O   1 
ATOM   8019  C CB  . ARG C 1 75  ? 109.027 154.889 98.789  1.00 25.49 ? 54   ARG C CB  1 
ATOM   8020  C CG  . ARG C 1 75  ? 110.521 154.890 98.567  1.00 25.49 ? 54   ARG C CG  1 
ATOM   8021  C CD  . ARG C 1 75  ? 111.137 156.193 99.016  1.00 25.49 ? 54   ARG C CD  1 
ATOM   8022  N NE  . ARG C 1 75  ? 111.168 157.177 97.940  1.00 25.49 ? 54   ARG C NE  1 
ATOM   8023  C CZ  . ARG C 1 75  ? 111.985 158.225 97.908  1.00 25.49 ? 54   ARG C CZ  1 
ATOM   8024  N NH1 . ARG C 1 75  ? 112.843 158.430 98.896  1.00 25.49 ? 54   ARG C NH1 1 
ATOM   8025  N NH2 . ARG C 1 75  ? 111.943 159.069 96.887  1.00 25.49 ? 54   ARG C NH2 1 
ATOM   8026  N N   . SER C 1 76  ? 106.621 152.235 99.586  1.00 21.93 ? 55   SER C N   1 
ATOM   8027  C CA  . SER C 1 76  ? 105.369 152.015 100.291 1.00 21.93 ? 55   SER C CA  1 
ATOM   8028  C C   . SER C 1 76  ? 105.538 152.297 101.777 1.00 21.93 ? 55   SER C C   1 
ATOM   8029  O O   . SER C 1 76  ? 106.603 152.063 102.353 1.00 21.93 ? 55   SER C O   1 
ATOM   8030  C CB  . SER C 1 76  ? 104.898 150.580 100.082 1.00 21.93 ? 55   SER C CB  1 
ATOM   8031  O OG  . SER C 1 76  ? 105.010 150.215 98.719  1.00 21.93 ? 55   SER C OG  1 
ATOM   8032  N N   . GLU C 1 77  ? 104.481 152.820 102.406 1.00 27.52 ? 56   GLU C N   1 
ATOM   8033  C CA  . GLU C 1 77  ? 104.563 153.153 103.827 1.00 27.52 ? 56   GLU C CA  1 
ATOM   8034  C C   . GLU C 1 77  ? 103.621 152.311 104.678 1.00 27.52 ? 56   GLU C C   1 
ATOM   8035  O O   . GLU C 1 77  ? 104.091 151.472 105.447 1.00 27.52 ? 56   GLU C O   1 
ATOM   8036  C CB  . GLU C 1 77  ? 104.268 154.643 104.018 1.00 27.52 ? 56   GLU C CB  1 
ATOM   8037  C CG  . GLU C 1 77  ? 104.993 155.574 103.060 1.00 27.52 ? 56   GLU C CG  1 
ATOM   8038  C CD  . GLU C 1 77  ? 106.325 156.047 103.594 1.00 27.52 ? 56   GLU C CD  1 
ATOM   8039  O OE1 . GLU C 1 77  ? 106.477 156.140 104.830 1.00 27.52 ? 56   GLU C OE1 1 
ATOM   8040  O OE2 . GLU C 1 77  ? 107.219 156.340 102.775 1.00 27.52 ? 56   GLU C OE2 1 
ATOM   8041  N N   . ALA C 1 78  ? 102.308 152.483 104.554 1.00 22.28 ? 57   ALA C N   1 
ATOM   8042  C CA  . ALA C 1 78  ? 101.390 151.734 105.402 1.00 22.28 ? 57   ALA C CA  1 
ATOM   8043  C C   . ALA C 1 78  ? 100.119 151.344 104.664 1.00 22.28 ? 57   ALA C C   1 
ATOM   8044  O O   . ALA C 1 78  ? 99.359  150.490 105.130 1.00 22.28 ? 57   ALA C O   1 
ATOM   8045  C CB  . ALA C 1 78  ? 101.045 152.543 106.652 1.00 22.28 ? 57   ALA C CB  1 
ATOM   8046  N N   . GLY C 1 79  ? 99.868  151.984 103.527 1.00 18.87 ? 58   GLY C N   1 
ATOM   8047  C CA  . GLY C 1 79  ? 98.634  151.762 102.804 1.00 18.87 ? 58   GLY C CA  1 
ATOM   8048  C C   . GLY C 1 79  ? 98.812  150.730 101.719 1.00 18.87 ? 58   GLY C C   1 
ATOM   8049  O O   . GLY C 1 79  ? 97.941  149.885 101.499 1.00 18.87 ? 58   GLY C O   1 
ATOM   8050  N N   . ASP C 1 80  ? 99.954  150.790 101.037 1.00 19.27 ? 59   ASP C N   1 
ATOM   8051  C CA  . ASP C 1 80  ? 100.258 149.787 100.027 1.00 19.27 ? 59   ASP C CA  1 
ATOM   8052  C C   . ASP C 1 80  ? 100.397 148.403 100.644 1.00 19.27 ? 59   ASP C C   1 
ATOM   8053  O O   . ASP C 1 80  ? 100.032 147.403 100.014 1.00 19.27 ? 59   ASP C O   1 
ATOM   8054  C CB  . ASP C 1 80  ? 101.526 150.173 99.279  1.00 19.27 ? 59   ASP C CB  1 
ATOM   8055  C CG  . ASP C 1 80  ? 101.741 149.343 98.041  1.00 19.27 ? 59   ASP C CG  1 
ATOM   8056  O OD1 . ASP C 1 80  ? 101.221 149.724 96.970  1.00 19.27 ? 59   ASP C OD1 1 
ATOM   8057  O OD2 . ASP C 1 80  ? 102.433 148.309 98.138  1.00 19.27 ? 59   ASP C OD2 1 
ATOM   8058  N N   . ILE C 1 81  ? 100.901 148.322 101.876 1.00 15.87 ? 60   ILE C N   1 
ATOM   8059  C CA  . ILE C 1 81  ? 100.925 147.031 102.548 1.00 15.87 ? 60   ILE C CA  1 
ATOM   8060  C C   . ILE C 1 81  ? 99.505  146.553 102.819 1.00 15.87 ? 60   ILE C C   1 
ATOM   8061  O O   . ILE C 1 81  ? 99.232  145.350 102.784 1.00 15.87 ? 60   ILE C O   1 
ATOM   8062  C CB  . ILE C 1 81  ? 101.774 147.100 103.833 1.00 15.87 ? 60   ILE C CB  1 
ATOM   8063  C CG1 . ILE C 1 81  ? 102.220 145.700 104.243 1.00 15.87 ? 60   ILE C CG1 1 
ATOM   8064  C CG2 . ILE C 1 81  ? 101.005 147.737 104.971 1.00 15.87 ? 60   ILE C CG2 1 
ATOM   8065  C CD1 . ILE C 1 81  ? 103.123 145.038 103.241 1.00 15.87 ? 60   ILE C CD1 1 
ATOM   8066  N N   . GLU C 1 82  ? 98.566  147.475 103.047 1.00 15.22 ? 61   GLU C N   1 
ATOM   8067  C CA  . GLU C 1 82  ? 97.182  147.063 103.241 1.00 15.22 ? 61   GLU C CA  1 
ATOM   8068  C C   . GLU C 1 82  ? 96.536  146.628 101.932 1.00 15.22 ? 61   GLU C C   1 
ATOM   8069  O O   . GLU C 1 82  ? 95.706  145.718 101.932 1.00 15.22 ? 61   GLU C O   1 
ATOM   8070  C CB  . GLU C 1 82  ? 96.376  148.185 103.887 1.00 15.22 ? 61   GLU C CB  1 
ATOM   8071  C CG  . GLU C 1 82  ? 96.649  148.371 105.373 1.00 15.22 ? 61   GLU C CG  1 
ATOM   8072  C CD  . GLU C 1 82  ? 96.803  147.061 106.122 1.00 15.22 ? 61   GLU C CD  1 
ATOM   8073  O OE1 . GLU C 1 82  ? 97.775  146.932 106.894 1.00 15.22 ? 61   GLU C OE1 1 
ATOM   8074  O OE2 . GLU C 1 82  ? 95.949  146.166 105.957 1.00 15.22 ? 61   GLU C OE2 1 
ATOM   8075  N N   . LEU C 1 83  ? 96.900  147.251 100.811 1.00 13.95 ? 62   LEU C N   1 
ATOM   8076  C CA  . LEU C 1 83  ? 96.446  146.743 99.519  1.00 13.95 ? 62   LEU C CA  1 
ATOM   8077  C C   . LEU C 1 83  ? 96.992  145.347 99.254  1.00 13.95 ? 62   LEU C C   1 
ATOM   8078  O O   . LEU C 1 83  ? 96.287  144.484 98.713  1.00 13.95 ? 62   LEU C O   1 
ATOM   8079  C CB  . LEU C 1 83  ? 96.848  147.699 98.396  1.00 13.95 ? 62   LEU C CB  1 
ATOM   8080  C CG  . LEU C 1 83  ? 95.907  148.863 98.079  1.00 13.95 ? 62   LEU C CG  1 
ATOM   8081  C CD1 . LEU C 1 83  ? 95.876  149.907 99.180  1.00 13.95 ? 62   LEU C CD1 1 
ATOM   8082  C CD2 . LEU C 1 83  ? 96.322  149.490 96.758  1.00 13.95 ? 62   LEU C CD2 1 
ATOM   8083  N N   . ALA C 1 84  ? 98.251  145.110 99.621  1.00 12.39 ? 63   ALA C N   1 
ATOM   8084  C CA  . ALA C 1 84  ? 98.820  143.773 99.492  1.00 12.39 ? 63   ALA C CA  1 
ATOM   8085  C C   . ALA C 1 84  ? 98.056  142.770 100.344 1.00 12.39 ? 63   ALA C C   1 
ATOM   8086  O O   . ALA C 1 84  ? 97.734  141.666 99.890  1.00 12.39 ? 63   ALA C O   1 
ATOM   8087  C CB  . ALA C 1 84  ? 100.293 143.792 99.884  1.00 12.39 ? 63   ALA C CB  1 
ATOM   8088  N N   . LEU C 1 85  ? 97.762  143.139 101.588 1.00 13.22 ? 64   LEU C N   1 
ATOM   8089  C CA  . LEU C 1 85  ? 96.998  142.251 102.452 1.00 13.22 ? 64   LEU C CA  1 
ATOM   8090  C C   . LEU C 1 85  ? 95.585  142.039 101.928 1.00 13.22 ? 64   LEU C C   1 
ATOM   8091  O O   . LEU C 1 85  ? 95.014  140.963 102.113 1.00 13.22 ? 64   LEU C O   1 
ATOM   8092  C CB  . LEU C 1 85  ? 96.970  142.809 103.872 1.00 13.22 ? 64   LEU C CB  1 
ATOM   8093  C CG  . LEU C 1 85  ? 98.340  142.824 104.548 1.00 13.22 ? 64   LEU C CG  1 
ATOM   8094  C CD1 . LEU C 1 85  ? 98.303  143.579 105.861 1.00 13.22 ? 64   LEU C CD1 1 
ATOM   8095  C CD2 . LEU C 1 85  ? 98.816  141.409 104.759 1.00 13.22 ? 64   LEU C CD2 1 
ATOM   8096  N N   . ASP C 1 86  ? 95.013  143.039 101.257 1.00 13.51 ? 65   ASP C N   1 
ATOM   8097  C CA  . ASP C 1 86  ? 93.700  142.867 100.648 1.00 13.51 ? 65   ASP C CA  1 
ATOM   8098  C C   . ASP C 1 86  ? 93.749  141.842 99.523  1.00 13.51 ? 65   ASP C C   1 
ATOM   8099  O O   . ASP C 1 86  ? 92.905  140.943 99.450  1.00 13.51 ? 65   ASP C O   1 
ATOM   8100  C CB  . ASP C 1 86  ? 93.181  144.205 100.126 1.00 13.51 ? 65   ASP C CB  1 
ATOM   8101  C CG  . ASP C 1 86  ? 92.840  145.172 101.238 1.00 13.51 ? 65   ASP C CG  1 
ATOM   8102  O OD1 . ASP C 1 86  ? 92.469  144.712 102.339 1.00 13.51 ? 65   ASP C OD1 1 
ATOM   8103  O OD2 . ASP C 1 86  ? 92.931  146.396 101.008 1.00 13.51 ? 65   ASP C OD2 1 
ATOM   8104  N N   . ALA C 1 87  ? 94.739  141.958 98.637  1.00 10.12 ? 66   ALA C N   1 
ATOM   8105  C CA  . ALA C 1 87  ? 94.858  140.988 97.552  1.00 10.12 ? 66   ALA C CA  1 
ATOM   8106  C C   . ALA C 1 87  ? 95.106  139.585 98.094  1.00 10.12 ? 66   ALA C C   1 
ATOM   8107  O O   . ALA C 1 87  ? 94.532  138.604 97.601  1.00 10.12 ? 66   ALA C O   1 
ATOM   8108  C CB  . ALA C 1 87  ? 95.972  141.400 96.595  1.00 10.12 ? 66   ALA C CB  1 
ATOM   8109  N N   . ALA C 1 88  ? 95.950  139.471 99.120  1.00 9.39  ? 67   ALA C N   1 
ATOM   8110  C CA  . ALA C 1 88  ? 96.221  138.170 99.719  1.00 9.39  ? 67   ALA C CA  1 
ATOM   8111  C C   . ALA C 1 88  ? 94.966  137.574 100.347 1.00 9.39  ? 67   ALA C C   1 
ATOM   8112  O O   . ALA C 1 88  ? 94.600  136.429 100.065 1.00 9.39  ? 67   ALA C O   1 
ATOM   8113  C CB  . ALA C 1 88  ? 97.338  138.299 100.750 1.00 9.39  ? 67   ALA C CB  1 
ATOM   8114  N N   . HIS C 1 89  ? 94.286  138.337 101.203 1.00 13.18 ? 68   HIS C N   1 
ATOM   8115  C CA  . HIS C 1 89  ? 93.070  137.852 101.840 1.00 13.18 ? 68   HIS C CA  1 
ATOM   8116  C C   . HIS C 1 89  ? 91.931  137.642 100.852 1.00 13.18 ? 68   HIS C C   1 
ATOM   8117  O O   . HIS C 1 89  ? 90.937  137.002 101.210 1.00 13.18 ? 68   HIS C O   1 
ATOM   8118  C CB  . HIS C 1 89  ? 92.626  138.828 102.928 1.00 13.18 ? 68   HIS C CB  1 
ATOM   8119  C CG  . HIS C 1 89  ? 93.143  138.493 104.291 1.00 13.18 ? 68   HIS C CG  1 
ATOM   8120  N ND1 . HIS C 1 89  ? 92.403  137.790 105.215 1.00 13.18 ? 68   HIS C ND1 1 
ATOM   8121  C CD2 . HIS C 1 89  ? 94.324  138.774 104.890 1.00 13.18 ? 68   HIS C CD2 1 
ATOM   8122  C CE1 . HIS C 1 89  ? 93.108  137.645 106.322 1.00 13.18 ? 68   HIS C CE1 1 
ATOM   8123  N NE2 . HIS C 1 89  ? 94.277  138.233 106.151 1.00 13.18 ? 68   HIS C NE2 1 
ATOM   8124  N N   . ALA C 1 90  ? 92.037  138.176 99.636  1.00 10.90 ? 69   ALA C N   1 
ATOM   8125  C CA  . ALA C 1 90  ? 91.021  137.941 98.620  1.00 10.90 ? 69   ALA C CA  1 
ATOM   8126  C C   . ALA C 1 90  ? 91.320  136.726 97.759  1.00 10.90 ? 69   ALA C C   1 
ATOM   8127  O O   . ALA C 1 90  ? 90.393  136.124 97.209  1.00 10.90 ? 69   ALA C O   1 
ATOM   8128  C CB  . ALA C 1 90  ? 90.874  139.174 97.726  1.00 10.90 ? 69   ALA C CB  1 
ATOM   8129  N N   . ALA C 1 91  ? 92.589  136.359 97.615  1.00 7.97  ? 70   ALA C N   1 
ATOM   8130  C CA  . ALA C 1 91  ? 92.953  135.134 96.918  1.00 7.97  ? 70   ALA C CA  1 
ATOM   8131  C C   . ALA C 1 91  ? 93.257  133.989 97.873  1.00 7.97  ? 70   ALA C C   1 
ATOM   8132  O O   . ALA C 1 91  ? 93.709  132.930 97.434  1.00 7.97  ? 70   ALA C O   1 
ATOM   8133  C CB  . ALA C 1 91  ? 94.150  135.378 96.004  1.00 7.97  ? 70   ALA C CB  1 
ATOM   8134  N N   . LYS C 1 92  ? 93.012  134.179 99.168  1.00 8.81  ? 71   LYS C N   1 
ATOM   8135  C CA  . LYS C 1 92  ? 93.381  133.187 100.170 1.00 8.81  ? 71   LYS C CA  1 
ATOM   8136  C C   . LYS C 1 92  ? 92.492  131.954 100.142 1.00 8.81  ? 71   LYS C C   1 
ATOM   8137  O O   . LYS C 1 92  ? 92.993  130.836 100.294 1.00 8.81  ? 71   LYS C O   1 
ATOM   8138  C CB  . LYS C 1 92  ? 93.313  133.816 101.555 1.00 8.81  ? 71   LYS C CB  1 
ATOM   8139  C CG  . LYS C 1 92  ? 93.704  132.906 102.680 1.00 8.81  ? 71   LYS C CG  1 
ATOM   8140  C CD  . LYS C 1 92  ? 93.731  133.677 103.984 1.00 8.81  ? 71   LYS C CD  1 
ATOM   8141  C CE  . LYS C 1 92  ? 92.325  134.022 104.436 1.00 8.81  ? 71   LYS C CE  1 
ATOM   8142  N NZ  . LYS C 1 92  ? 91.566  132.812 104.837 1.00 8.81  ? 71   LYS C NZ  1 
ATOM   8143  N N   . GLU C 1 93  ? 91.185  132.128 99.960  1.00 9.89  ? 72   GLU C N   1 
ATOM   8144  C CA  . GLU C 1 93  ? 90.261  131.008 100.099 1.00 9.89  ? 72   GLU C CA  1 
ATOM   8145  C C   . GLU C 1 93  ? 90.283  130.085 98.888  1.00 9.89  ? 72   GLU C C   1 
ATOM   8146  O O   . GLU C 1 93  ? 90.123  128.870 99.037  1.00 9.89  ? 72   GLU C O   1 
ATOM   8147  C CB  . GLU C 1 93  ? 88.846  131.534 100.338 1.00 9.89  ? 72   GLU C CB  1 
ATOM   8148  C CG  . GLU C 1 93  ? 87.820  130.460 100.641 1.00 9.89  ? 72   GLU C CG  1 
ATOM   8149  C CD  . GLU C 1 93  ? 87.709  130.175 102.124 1.00 9.89  ? 72   GLU C CD  1 
ATOM   8150  O OE1 . GLU C 1 93  ? 86.794  129.423 102.520 1.00 9.89  ? 72   GLU C OE1 1 
ATOM   8151  O OE2 . GLU C 1 93  ? 88.538  130.703 102.895 1.00 9.89  ? 72   GLU C OE2 1 
ATOM   8152  N N   . LYS C 1 94  ? 90.478  130.635 97.693  1.00 6.32  ? 73   LYS C N   1 
ATOM   8153  C CA  . LYS C 1 94  ? 90.476  129.847 96.472  1.00 6.32  ? 73   LYS C CA  1 
ATOM   8154  C C   . LYS C 1 94  ? 91.817  129.185 96.194  1.00 6.32  ? 73   LYS C C   1 
ATOM   8155  O O   . LYS C 1 94  ? 91.878  128.251 95.387  1.00 6.32  ? 73   LYS C O   1 
ATOM   8156  C CB  . LYS C 1 94  ? 90.077  130.740 95.291  1.00 6.32  ? 73   LYS C CB  1 
ATOM   8157  C CG  . LYS C 1 94  ? 89.990  130.044 93.945  1.00 6.32  ? 73   LYS C CG  1 
ATOM   8158  C CD  . LYS C 1 94  ? 89.775  131.037 92.816  1.00 6.32  ? 73   LYS C CD  1 
ATOM   8159  C CE  . LYS C 1 94  ? 90.111  130.413 91.473  1.00 6.32  ? 73   LYS C CE  1 
ATOM   8160  N NZ  . LYS C 1 94  ? 89.323  129.174 91.227  1.00 6.32  ? 73   LYS C NZ  1 
ATOM   8161  N N   . TRP C 1 95  ? 92.888  129.628 96.849  1.00 2.65  ? 74   TRP C N   1 
ATOM   8162  C CA  . TRP C 1 95  ? 94.200  129.040 96.613  1.00 2.65  ? 74   TRP C CA  1 
ATOM   8163  C C   . TRP C 1 95  ? 94.472  127.865 97.537  1.00 2.65  ? 74   TRP C C   1 
ATOM   8164  O O   . TRP C 1 95  ? 95.027  126.853 97.101  1.00 2.65  ? 74   TRP C O   1 
ATOM   8165  C CB  . TRP C 1 95  ? 95.289  130.097 96.776  1.00 2.65  ? 74   TRP C CB  1 
ATOM   8166  C CG  . TRP C 1 95  ? 96.685  129.580 96.611  1.00 2.65  ? 74   TRP C CG  1 
ATOM   8167  C CD1 . TRP C 1 95  ? 97.664  129.581 97.548  1.00 2.65  ? 74   TRP C CD1 1 
ATOM   8168  C CD2 . TRP C 1 95  ? 97.260  129.011 95.433  1.00 2.65  ? 74   TRP C CD2 1 
ATOM   8169  N NE1 . TRP C 1 95  ? 98.811  129.042 97.036  1.00 2.65  ? 74   TRP C NE1 1 
ATOM   8170  C CE2 . TRP C 1 95  ? 98.590  128.686 95.735  1.00 2.65  ? 74   TRP C CE2 1 
ATOM   8171  C CE3 . TRP C 1 95  ? 96.780  128.745 94.151  1.00 2.65  ? 74   TRP C CE3 1 
ATOM   8172  C CZ2 . TRP C 1 95  ? 99.442  128.113 94.810  1.00 2.65  ? 74   TRP C CZ2 1 
ATOM   8173  C CZ3 . TRP C 1 95  ? 97.626  128.174 93.238  1.00 2.65  ? 74   TRP C CZ3 1 
ATOM   8174  C CH2 . TRP C 1 95  ? 98.941  127.864 93.569  1.00 2.65  ? 74   TRP C CH2 1 
ATOM   8175  N N   . GLY C 1 96  ? 94.084  127.969 98.805  1.00 3.88  ? 75   GLY C N   1 
ATOM   8176  C CA  . GLY C 1 96  ? 94.209  126.829 99.688  1.00 3.88  ? 75   GLY C CA  1 
ATOM   8177  C C   . GLY C 1 96  ? 93.217  125.728 99.409  1.00 3.88  ? 75   GLY C C   1 
ATOM   8178  O O   . GLY C 1 96  ? 93.366  124.628 99.950  1.00 3.88  ? 75   GLY C O   1 
ATOM   8179  N N   . ALA C 1 97  ? 92.208  126.004 98.586  1.00 4.46  ? 76   ALA C N   1 
ATOM   8180  C CA  . ALA C 1 97  ? 91.252  125.014 98.119  1.00 4.46  ? 76   ALA C CA  1 
ATOM   8181  C C   . ALA C 1 97  ? 91.739  124.265 96.891  1.00 4.46  ? 76   ALA C C   1 
ATOM   8182  O O   . ALA C 1 97  ? 91.128  123.262 96.512  1.00 4.46  ? 76   ALA C O   1 
ATOM   8183  C CB  . ALA C 1 97  ? 89.918  125.689 97.801  1.00 4.46  ? 76   ALA C CB  1 
ATOM   8184  N N   . THR C 1 98  ? 92.812  124.729 96.264  1.00 1.40  ? 77   THR C N   1 
ATOM   8185  C CA  . THR C 1 98  ? 93.349  124.074 95.086  1.00 1.40  ? 77   THR C CA  1 
ATOM   8186  C C   . THR C 1 98  ? 93.923  122.716 95.472  1.00 1.40  ? 77   THR C C   1 
ATOM   8187  O O   . THR C 1 98  ? 94.348  122.499 96.609  1.00 1.40  ? 77   THR C O   1 
ATOM   8188  C CB  . THR C 1 98  ? 94.418  124.962 94.448  1.00 1.40  ? 77   THR C CB  1 
ATOM   8189  O OG1 . THR C 1 98  ? 93.834  126.224 94.116  1.00 1.40  ? 77   THR C OG1 1 
ATOM   8190  C CG2 . THR C 1 98  ? 94.959  124.355 93.173  1.00 1.40  ? 77   THR C CG2 1 
ATOM   8191  N N   . SER C 1 99  ? 93.905  121.785 94.520  1.00 1.55  ? 78   SER C N   1 
ATOM   8192  C CA  . SER C 1 99  ? 94.469  120.471 94.765  1.00 1.55  ? 78   SER C CA  1 
ATOM   8193  C C   . SER C 1 99  ? 95.967  120.595 95.017  1.00 1.55  ? 78   SER C C   1 
ATOM   8194  O O   . SER C 1 99  ? 96.625  121.477 94.461  1.00 1.55  ? 78   SER C O   1 
ATOM   8195  C CB  . SER C 1 99  ? 94.229  119.548 93.575  1.00 1.55  ? 78   SER C CB  1 
ATOM   8196  O OG  . SER C 1 99  ? 92.867  119.531 93.205  1.00 1.55  ? 78   SER C OG  1 
ATOM   8197  N N   . PRO C 1 100 ? 96.531  119.736 95.866  1.00 1.27  ? 79   PRO C N   1 
ATOM   8198  C CA  . PRO C 1 100 ? 97.994  119.672 95.959  1.00 1.27  ? 79   PRO C CA  1 
ATOM   8199  C C   . PRO C 1 100 ? 98.669  119.345 94.638  1.00 1.27  ? 79   PRO C C   1 
ATOM   8200  O O   . PRO C 1 100 ? 99.786  119.813 94.400  1.00 1.27  ? 79   PRO C O   1 
ATOM   8201  C CB  . PRO C 1 100 ? 98.216  118.576 97.003  1.00 1.27  ? 79   PRO C CB  1 
ATOM   8202  C CG  . PRO C 1 100 ? 97.030  118.674 97.869  1.00 1.27  ? 79   PRO C CG  1 
ATOM   8203  C CD  . PRO C 1 100 ? 95.883  118.996 96.960  1.00 1.27  ? 79   PRO C CD  1 
ATOM   8204  N N   . ALA C 1 101 ? 98.023  118.574 93.760  1.00 0.65  ? 80   ALA C N   1 
ATOM   8205  C CA  . ALA C 1 101 ? 98.643  118.240 92.482  1.00 0.65  ? 80   ALA C CA  1 
ATOM   8206  C C   . ALA C 1 101 ? 98.626  119.424 91.522  1.00 0.65  ? 80   ALA C C   1 
ATOM   8207  O O   . ALA C 1 101 ? 99.604  119.663 90.806  1.00 0.65  ? 80   ALA C O   1 
ATOM   8208  C CB  . ALA C 1 101 ? 97.945  117.037 91.856  1.00 0.65  ? 80   ALA C CB  1 
ATOM   8209  N N   . GLU C 1 102 ? 97.527  120.183 91.495  1.00 1.50  ? 81   GLU C N   1 
ATOM   8210  C CA  . GLU C 1 102 ? 97.478  121.378 90.657  1.00 1.50  ? 81   GLU C CA  1 
ATOM   8211  C C   . GLU C 1 102 ? 98.431  122.445 91.172  1.00 1.50  ? 81   GLU C C   1 
ATOM   8212  O O   . GLU C 1 102 ? 99.117  123.113 90.390  1.00 1.50  ? 81   GLU C O   1 
ATOM   8213  C CB  . GLU C 1 102 ? 96.051  121.916 90.598  1.00 1.50  ? 81   GLU C CB  1 
ATOM   8214  C CG  . GLU C 1 102 ? 95.060  120.950 89.975  1.00 1.50  ? 81   GLU C CG  1 
ATOM   8215  C CD  . GLU C 1 102 ? 93.687  121.558 89.793  1.00 1.50  ? 81   GLU C CD  1 
ATOM   8216  O OE1 . GLU C 1 102 ? 93.296  122.408 90.623  1.00 1.50  ? 81   GLU C OE1 1 
ATOM   8217  O OE2 . GLU C 1 102 ? 92.996  121.186 88.822  1.00 1.50  ? 81   GLU C OE2 1 
ATOM   8218  N N   . ARG C 1 103 ? 98.486  122.609 92.490  1.00 1.36  ? 82   ARG C N   1 
ATOM   8219  C CA  . ARG C 1 103 ? 99.439  123.524 93.102  1.00 1.36  ? 82   ARG C CA  1 
ATOM   8220  C C   . ARG C 1 103 ? 100.873 123.129 92.762  1.00 1.36  ? 82   ARG C C   1 
ATOM   8221  O O   . ARG C 1 103 ? 101.697 123.981 92.396  1.00 1.36  ? 82   ARG C O   1 
ATOM   8222  C CB  . ARG C 1 103 ? 99.201  123.527 94.608  1.00 1.36  ? 82   ARG C CB  1 
ATOM   8223  C CG  . ARG C 1 103 ? 99.508  124.807 95.284  1.00 1.36  ? 82   ARG C CG  1 
ATOM   8224  C CD  . ARG C 1 103 ? 99.245  124.729 96.767  1.00 1.36  ? 82   ARG C CD  1 
ATOM   8225  N NE  . ARG C 1 103 ? 97.857  124.422 97.084  1.00 1.36  ? 82   ARG C NE  1 
ATOM   8226  C CZ  . ARG C 1 103 ? 97.484  123.547 98.008  1.00 1.36  ? 82   ARG C CZ  1 
ATOM   8227  N NH1 . ARG C 1 103 ? 98.394  122.892 98.706  1.00 1.36  ? 82   ARG C NH1 1 
ATOM   8228  N NH2 . ARG C 1 103 ? 96.202  123.327 98.237  1.00 1.36  ? 82   ARG C NH2 1 
ATOM   8229  N N   . ALA C 1 104 ? 101.180 121.834 92.844  1.00 1.30  ? 83   ALA C N   1 
ATOM   8230  C CA  . ALA C 1 104 ? 102.514 121.364 92.499  1.00 1.30  ? 83   ALA C CA  1 
ATOM   8231  C C   . ALA C 1 104 ? 102.821 121.585 91.027  1.00 1.30  ? 83   ALA C C   1 
ATOM   8232  O O   . ALA C 1 104 ? 103.959 121.900 90.670  1.00 1.30  ? 83   ALA C O   1 
ATOM   8233  C CB  . ALA C 1 104 ? 102.658 119.892 92.859  1.00 1.30  ? 83   ALA C CB  1 
ATOM   8234  N N   . ASN C 1 105 ? 101.828 121.413 90.151  1.00 1.36  ? 84   ASN C N   1 
ATOM   8235  C CA  . ASN C 1 105 ? 102.064 121.646 88.729  1.00 1.36  ? 84   ASN C CA  1 
ATOM   8236  C C   . ASN C 1 105 ? 102.319 123.120 88.444  1.00 1.36  ? 84   ASN C C   1 
ATOM   8237  O O   . ASN C 1 105 ? 103.135 123.460 87.578  1.00 1.36  ? 84   ASN C O   1 
ATOM   8238  C CB  . ASN C 1 105 ? 100.885 121.138 87.908  1.00 1.36  ? 84   ASN C CB  1 
ATOM   8239  C CG  . ASN C 1 105 ? 101.139 121.221 86.421  1.00 1.36  ? 84   ASN C CG  1 
ATOM   8240  O OD1 . ASN C 1 105 ? 102.287 121.220 85.976  1.00 1.36  ? 84   ASN C OD1 1 
ATOM   8241  N ND2 . ASN C 1 105 ? 100.069 121.297 85.641  1.00 1.36  ? 84   ASN C ND2 1 
ATOM   8242  N N   . ILE C 1 106 ? 101.630 124.011 89.160  1.00 1.21  ? 85   ILE C N   1 
ATOM   8243  C CA  . ILE C 1 106 ? 101.928 125.435 89.043  1.00 1.21  ? 85   ILE C CA  1 
ATOM   8244  C C   . ILE C 1 106 ? 103.364 125.710 89.465  1.00 1.21  ? 85   ILE C C   1 
ATOM   8245  O O   . ILE C 1 106 ? 104.089 126.464 88.805  1.00 1.21  ? 85   ILE C O   1 
ATOM   8246  C CB  . ILE C 1 106 ? 100.932 126.266 89.868  1.00 1.21  ? 85   ILE C CB  1 
ATOM   8247  C CG1 . ILE C 1 106 ? 99.538  126.201 89.250  1.00 1.21  ? 85   ILE C CG1 1 
ATOM   8248  C CG2 . ILE C 1 106 ? 101.394 127.703 89.965  1.00 1.21  ? 85   ILE C CG2 1 
ATOM   8249  C CD1 . ILE C 1 106 ? 98.444  126.561 90.211  1.00 1.21  ? 85   ILE C CD1 1 
ATOM   8250  N N   . MET C 1 107 ? 103.798 125.099 90.570  1.00 1.20  ? 86   MET C N   1 
ATOM   8251  C CA  . MET C 1 107 ? 105.182 125.266 91.011  1.00 1.20  ? 86   MET C CA  1 
ATOM   8252  C C   . MET C 1 107 ? 106.172 124.742 89.978  1.00 1.20  ? 86   MET C C   1 
ATOM   8253  O O   . MET C 1 107 ? 107.237 125.334 89.770  1.00 1.20  ? 86   MET C O   1 
ATOM   8254  C CB  . MET C 1 107 ? 105.389 124.564 92.344  1.00 1.20  ? 86   MET C CB  1 
ATOM   8255  C CG  . MET C 1 107 ? 104.542 125.113 93.451  1.00 1.20  ? 86   MET C CG  1 
ATOM   8256  S SD  . MET C 1 107 ? 105.133 124.525 95.036  1.00 1.20  ? 86   MET C SD  1 
ATOM   8257  C CE  . MET C 1 107 ? 106.684 125.397 95.187  1.00 1.20  ? 86   MET C CE  1 
ATOM   8258  N N   . LEU C 1 108 ? 105.847 123.628 89.328  1.00 1.38  ? 87   LEU C N   1 
ATOM   8259  C CA  . LEU C 1 108 ? 106.742 123.074 88.316  1.00 1.38  ? 87   LEU C CA  1 
ATOM   8260  C C   . LEU C 1 108 ? 106.831 123.980 87.097  1.00 1.38  ? 87   LEU C C   1 
ATOM   8261  O O   . LEU C 1 108 ? 107.909 124.145 86.518  1.00 1.38  ? 87   LEU C O   1 
ATOM   8262  C CB  . LEU C 1 108 ? 106.276 121.680 87.910  1.00 1.38  ? 87   LEU C CB  1 
ATOM   8263  C CG  . LEU C 1 108 ? 106.365 120.648 89.026  1.00 1.38  ? 87   LEU C CG  1 
ATOM   8264  C CD1 . LEU C 1 108 ? 105.785 119.333 88.582  1.00 1.38  ? 87   LEU C CD1 1 
ATOM   8265  C CD2 . LEU C 1 108 ? 107.799 120.491 89.455  1.00 1.38  ? 87   LEU C CD2 1 
ATOM   8266  N N   . LYS C 1 109 ? 105.708 124.568 86.685  1.00 1.78  ? 88   LYS C N   1 
ATOM   8267  C CA  . LYS C 1 109 ? 105.750 125.540 85.597  1.00 1.78  ? 88   LYS C CA  1 
ATOM   8268  C C   . LYS C 1 109 ? 106.569 126.763 85.984  1.00 1.78  ? 88   LYS C C   1 
ATOM   8269  O O   . LYS C 1 109 ? 107.319 127.303 85.163  1.00 1.78  ? 88   LYS C O   1 
ATOM   8270  C CB  . LYS C 1 109 ? 104.334 125.946 85.201  1.00 1.78  ? 88   LYS C CB  1 
ATOM   8271  C CG  . LYS C 1 109 ? 103.700 124.999 84.216  1.00 1.78  ? 88   LYS C CG  1 
ATOM   8272  C CD  . LYS C 1 109 ? 102.321 125.455 83.818  1.00 1.78  ? 88   LYS C CD  1 
ATOM   8273  C CE  . LYS C 1 109 ? 101.438 124.263 83.527  1.00 1.78  ? 88   LYS C CE  1 
ATOM   8274  N NZ  . LYS C 1 109 ? 102.234 123.130 82.978  1.00 1.78  ? 88   LYS C NZ  1 
ATOM   8275  N N   . ILE C 1 110 ? 106.423 127.223 87.229  1.00 2.11  ? 89   ILE C N   1 
ATOM   8276  C CA  . ILE C 1 110 ? 107.242 128.328 87.718  1.00 2.11  ? 89   ILE C CA  1 
ATOM   8277  C C   . ILE C 1 110 ? 108.718 127.988 87.579  1.00 2.11  ? 89   ILE C C   1 
ATOM   8278  O O   . ILE C 1 110 ? 109.512 128.780 87.061  1.00 2.11  ? 89   ILE C O   1 
ATOM   8279  C CB  . ILE C 1 110 ? 106.884 128.659 89.176  1.00 2.11  ? 89   ILE C CB  1 
ATOM   8280  C CG1 . ILE C 1 110 ? 105.577 129.437 89.246  1.00 2.11  ? 89   ILE C CG1 1 
ATOM   8281  C CG2 . ILE C 1 110 ? 107.989 129.459 89.822  1.00 2.11  ? 89   ILE C CG2 1 
ATOM   8282  C CD1 . ILE C 1 110 ? 105.148 129.751 90.653  1.00 2.11  ? 89   ILE C CD1 1 
ATOM   8283  N N   . ALA C 1 111 ? 109.102 126.793 88.028  1.00 3.54  ? 90   ALA C N   1 
ATOM   8284  C CA  . ALA C 1 111 ? 110.504 126.396 87.969  1.00 3.54  ? 90   ALA C CA  1 
ATOM   8285  C C   . ALA C 1 111 ? 110.992 126.288 86.532  1.00 3.54  ? 90   ALA C C   1 
ATOM   8286  O O   . ALA C 1 111 ? 112.124 126.679 86.221  1.00 3.54  ? 90   ALA C O   1 
ATOM   8287  C CB  . ALA C 1 111 ? 110.702 125.075 88.703  1.00 3.54  ? 90   ALA C CB  1 
ATOM   8288  N N   . ASP C 1 112 ? 110.153 125.766 85.636  1.00 5.03  ? 91   ASP C N   1 
ATOM   8289  C CA  . ASP C 1 112 ? 110.579 125.585 84.252  1.00 5.03  ? 91   ASP C CA  1 
ATOM   8290  C C   . ASP C 1 112 ? 110.710 126.912 83.517  1.00 5.03  ? 91   ASP C C   1 
ATOM   8291  O O   . ASP C 1 112 ? 111.585 127.054 82.657  1.00 5.03  ? 91   ASP C O   1 
ATOM   8292  C CB  . ASP C 1 112 ? 109.609 124.669 83.514  1.00 5.03  ? 91   ASP C CB  1 
ATOM   8293  C CG  . ASP C 1 112 ? 110.313 123.746 82.542  1.00 5.03  ? 91   ASP C CG  1 
ATOM   8294  O OD1 . ASP C 1 112 ? 111.553 123.840 82.425  1.00 5.03  ? 91   ASP C OD1 1 
ATOM   8295  O OD2 . ASP C 1 112 ? 109.631 122.924 81.896  1.00 5.03  ? 91   ASP C OD2 1 
ATOM   8296  N N   . ARG C 1 113 ? 109.853 127.888 83.823  1.00 5.06  ? 92   ARG C N   1 
ATOM   8297  C CA  . ARG C 1 113 ? 110.038 129.210 83.234  1.00 5.06  ? 92   ARG C CA  1 
ATOM   8298  C C   . ARG C 1 113 ? 111.204 129.946 83.872  1.00 5.06  ? 92   ARG C C   1 
ATOM   8299  O O   . ARG C 1 113 ? 111.835 130.781 83.219  1.00 5.06  ? 92   ARG C O   1 
ATOM   8300  C CB  . ARG C 1 113 ? 108.766 130.047 83.357  1.00 5.06  ? 92   ARG C CB  1 
ATOM   8301  C CG  . ARG C 1 113 ? 108.750 131.239 82.417  1.00 5.06  ? 92   ARG C CG  1 
ATOM   8302  C CD  . ARG C 1 113 ? 107.546 132.129 82.638  1.00 5.06  ? 92   ARG C CD  1 
ATOM   8303  N NE  . ARG C 1 113 ? 106.296 131.465 82.290  1.00 5.06  ? 92   ARG C NE  1 
ATOM   8304  C CZ  . ARG C 1 113 ? 105.100 132.036 82.382  1.00 5.06  ? 92   ARG C CZ  1 
ATOM   8305  N NH1 . ARG C 1 113 ? 104.990 133.285 82.805  1.00 5.06  ? 92   ARG C NH1 1 
ATOM   8306  N NH2 . ARG C 1 113 ? 104.014 131.358 82.048  1.00 5.06  ? 92   ARG C NH2 1 
ATOM   8307  N N   . MET C 1 114 ? 111.502 129.656 85.137  1.00 5.44  ? 93   MET C N   1 
ATOM   8308  C CA  . MET C 1 114 ? 112.699 130.211 85.751  1.00 5.44  ? 93   MET C CA  1 
ATOM   8309  C C   . MET C 1 114 ? 113.961 129.632 85.134  1.00 5.44  ? 93   MET C C   1 
ATOM   8310  O O   . MET C 1 114 ? 114.998 130.301 85.109  1.00 5.44  ? 93   MET C O   1 
ATOM   8311  C CB  . MET C 1 114 ? 112.686 129.952 87.253  1.00 5.44  ? 93   MET C CB  1 
ATOM   8312  C CG  . MET C 1 114 ? 111.929 130.984 88.036  1.00 5.44  ? 93   MET C CG  1 
ATOM   8313  S SD  . MET C 1 114 ? 111.882 130.615 89.792  1.00 5.44  ? 93   MET C SD  1 
ATOM   8314  C CE  . MET C 1 114 ? 113.621 130.469 90.154  1.00 5.44  ? 93   MET C CE  1 
ATOM   8315  N N   . GLU C 1 115 ? 113.900 128.399 84.635  1.00 6.80  ? 94   GLU C N   1 
ATOM   8316  C CA  . GLU C 1 115 ? 115.103 127.754 84.121  1.00 6.80  ? 94   GLU C CA  1 
ATOM   8317  C C   . GLU C 1 115 ? 115.547 128.364 82.798  1.00 6.80  ? 94   GLU C C   1 
ATOM   8318  O O   . GLU C 1 115 ? 116.688 128.816 82.667  1.00 6.80  ? 94   GLU C O   1 
ATOM   8319  C CB  . GLU C 1 115 ? 114.877 126.253 83.969  1.00 6.80  ? 94   GLU C CB  1 
ATOM   8320  C CG  . GLU C 1 115 ? 115.949 125.573 83.143  1.00 6.80  ? 94   GLU C CG  1 
ATOM   8321  C CD  . GLU C 1 115 ? 115.826 124.067 83.145  1.00 6.80  ? 94   GLU C CD  1 
ATOM   8322  O OE1 . GLU C 1 115 ? 115.050 123.534 83.966  1.00 6.80  ? 94   GLU C OE1 1 
ATOM   8323  O OE2 . GLU C 1 115 ? 116.500 123.416 82.319  1.00 6.80  ? 94   GLU C OE2 1 
ATOM   8324  N N   . ARG C 1 116 ? 114.669 128.370 81.790  1.00 8.14  ? 95   ARG C N   1 
ATOM   8325  C CA  . ARG C 1 116 ? 115.085 128.828 80.465  1.00 8.14  ? 95   ARG C CA  1 
ATOM   8326  C C   . ARG C 1 116 ? 115.417 130.312 80.428  1.00 8.14  ? 95   ARG C C   1 
ATOM   8327  O O   . ARG C 1 116 ? 116.033 130.767 79.460  1.00 8.14  ? 95   ARG C O   1 
ATOM   8328  C CB  . ARG C 1 116 ? 114.009 128.523 79.425  1.00 8.14  ? 95   ARG C CB  1 
ATOM   8329  C CG  . ARG C 1 116 ? 113.958 127.070 78.997  1.00 8.14  ? 95   ARG C CG  1 
ATOM   8330  C CD  . ARG C 1 116 ? 113.094 126.898 77.764  1.00 8.14  ? 95   ARG C CD  1 
ATOM   8331  N NE  . ARG C 1 116 ? 111.918 127.758 77.799  1.00 8.14  ? 95   ARG C NE  1 
ATOM   8332  C CZ  . ARG C 1 116 ? 110.752 127.453 77.241  1.00 8.14  ? 95   ARG C CZ  1 
ATOM   8333  N NH1 . ARG C 1 116 ? 110.601 126.302 76.602  1.00 8.14  ? 95   ARG C NH1 1 
ATOM   8334  N NH2 . ARG C 1 116 ? 109.736 128.300 77.323  1.00 8.14  ? 95   ARG C NH2 1 
ATOM   8335  N N   . ASN C 1 117 ? 115.027 131.068 81.449  1.00 8.79  ? 96   ASN C N   1 
ATOM   8336  C CA  . ASN C 1 117 ? 115.422 132.462 81.624  1.00 8.79  ? 96   ASN C CA  1 
ATOM   8337  C C   . ASN C 1 117 ? 116.545 132.596 82.639  1.00 8.79  ? 96   ASN C C   1 
ATOM   8338  O O   . ASN C 1 117 ? 116.571 133.546 83.419  1.00 8.79  ? 96   ASN C O   1 
ATOM   8339  C CB  . ASN C 1 117 ? 114.222 133.301 82.044  1.00 8.79  ? 96   ASN C CB  1 
ATOM   8340  C CG  . ASN C 1 117 ? 113.214 133.459 80.937  1.00 8.79  ? 96   ASN C CG  1 
ATOM   8341  O OD1 . ASN C 1 117 ? 112.073 133.022 81.055  1.00 8.79  ? 96   ASN C OD1 1 
ATOM   8342  N ND2 . ASN C 1 117 ? 113.630 134.086 79.847  1.00 8.79  ? 96   ASN C ND2 1 
ATOM   8343  N N   . LEU C 1 118 ? 117.470 131.637 82.667  1.00 9.18  ? 97   LEU C N   1 
ATOM   8344  C CA  . LEU C 1 118 ? 118.476 131.609 83.724  1.00 9.18  ? 97   LEU C CA  1 
ATOM   8345  C C   . LEU C 1 118 ? 119.384 132.827 83.648  1.00 9.18  ? 97   LEU C C   1 
ATOM   8346  O O   . LEU C 1 118 ? 119.643 133.490 84.661  1.00 9.18  ? 97   LEU C O   1 
ATOM   8347  C CB  . LEU C 1 118 ? 119.301 130.327 83.624  1.00 9.18  ? 97   LEU C CB  1 
ATOM   8348  C CG  . LEU C 1 118 ? 119.778 129.749 84.953  1.00 9.18  ? 97   LEU C CG  1 
ATOM   8349  C CD1 . LEU C 1 118 ? 118.582 129.580 85.848  1.00 9.18  ? 97   LEU C CD1 1 
ATOM   8350  C CD2 . LEU C 1 118 ? 120.481 128.426 84.752  1.00 9.18  ? 97   LEU C CD2 1 
ATOM   8351  N N   . GLU C 1 119 ? 119.865 133.140 82.444  1.00 11.69 ? 98   GLU C N   1 
ATOM   8352  C CA  . GLU C 1 119 ? 120.803 134.241 82.277  1.00 11.69 ? 98   GLU C CA  1 
ATOM   8353  C C   . GLU C 1 119 ? 120.188 135.560 82.713  1.00 11.69 ? 98   GLU C C   1 
ATOM   8354  O O   . GLU C 1 119 ? 120.865 136.394 83.320  1.00 11.69 ? 98   GLU C O   1 
ATOM   8355  C CB  . GLU C 1 119 ? 121.259 134.320 80.822  1.00 11.69 ? 98   GLU C CB  1 
ATOM   8356  C CG  . GLU C 1 119 ? 122.451 133.441 80.496  1.00 11.69 ? 98   GLU C CG  1 
ATOM   8357  C CD  . GLU C 1 119 ? 122.067 131.988 80.331  1.00 11.69 ? 98   GLU C CD  1 
ATOM   8358  O OE1 . GLU C 1 119 ? 122.967 131.125 80.385  1.00 11.69 ? 98   GLU C OE1 1 
ATOM   8359  O OE2 . GLU C 1 119 ? 120.865 131.706 80.149  1.00 11.69 ? 98   GLU C OE2 1 
ATOM   8360  N N   . LEU C 1 120 ? 118.903 135.762 82.433  1.00 11.87 ? 99   LEU C N   1 
ATOM   8361  C CA  . LEU C 1 120 ? 118.285 137.049 82.727  1.00 11.87 ? 99   LEU C CA  1 
ATOM   8362  C C   . LEU C 1 120 ? 118.172 137.281 84.230  1.00 11.87 ? 99   LEU C C   1 
ATOM   8363  O O   . LEU C 1 120 ? 118.546 138.346 84.731  1.00 11.87 ? 99   LEU C O   1 
ATOM   8364  C CB  . LEU C 1 120 ? 116.918 137.132 82.059  1.00 11.87 ? 99   LEU C CB  1 
ATOM   8365  C CG  . LEU C 1 120 ? 116.236 138.487 82.202  1.00 11.87 ? 99   LEU C CG  1 
ATOM   8366  C CD1 . LEU C 1 120 ? 117.093 139.557 81.543  1.00 11.87 ? 99   LEU C CD1 1 
ATOM   8367  C CD2 . LEU C 1 120 ? 114.856 138.444 81.577  1.00 11.87 ? 99   LEU C CD2 1 
ATOM   8368  N N   . LEU C 1 121 ? 117.671 136.290 84.970  1.00 9.50  ? 100  LEU C N   1 
ATOM   8369  C CA  . LEU C 1 121 ? 117.544 136.450 86.416  1.00 9.50  ? 100  LEU C CA  1 
ATOM   8370  C C   . LEU C 1 121 ? 118.909 136.483 87.091  1.00 9.50  ? 100  LEU C C   1 
ATOM   8371  O O   . LEU C 1 121 ? 119.108 137.217 88.068  1.00 9.50  ? 100  LEU C O   1 
ATOM   8372  C CB  . LEU C 1 121 ? 116.692 135.327 86.994  1.00 9.50  ? 100  LEU C CB  1 
ATOM   8373  C CG  . LEU C 1 121 ? 115.260 135.221 86.491  1.00 9.50  ? 100  LEU C CG  1 
ATOM   8374  C CD1 . LEU C 1 121 ? 114.766 133.799 86.657  1.00 9.50  ? 100  LEU C CD1 1 
ATOM   8375  C CD2 . LEU C 1 121 ? 114.377 136.185 87.248  1.00 9.50  ? 100  LEU C CD2 1 
ATOM   8376  N N   . ALA C 1 122 ? 119.865 135.698 86.585  1.00 11.38 ? 101  ALA C N   1 
ATOM   8377  C CA  . ALA C 1 122 ? 121.215 135.745 87.134  1.00 11.38 ? 101  ALA C CA  1 
ATOM   8378  C C   . ALA C 1 122 ? 121.848 137.115 86.925  1.00 11.38 ? 101  ALA C C   1 
ATOM   8379  O O   . ALA C 1 122 ? 122.470 137.666 87.842  1.00 11.38 ? 101  ALA C O   1 
ATOM   8380  C CB  . ALA C 1 122 ? 122.072 134.652 86.505  1.00 11.38 ? 101  ALA C CB  1 
ATOM   8381  N N   . THR C 1 123 ? 121.692 137.685 85.728  1.00 12.85 ? 102  THR C N   1 
ATOM   8382  C CA  . THR C 1 123 ? 122.219 139.014 85.455  1.00 12.85 ? 102  THR C CA  1 
ATOM   8383  C C   . THR C 1 123 ? 121.530 140.060 86.312  1.00 12.85 ? 102  THR C C   1 
ATOM   8384  O O   . THR C 1 123 ? 122.174 140.997 86.795  1.00 12.85 ? 102  THR C O   1 
ATOM   8385  C CB  . THR C 1 123 ? 122.056 139.339 83.971  1.00 12.85 ? 102  THR C CB  1 
ATOM   8386  O OG1 . THR C 1 123 ? 122.865 138.446 83.198  1.00 12.85 ? 102  THR C OG1 1 
ATOM   8387  C CG2 . THR C 1 123 ? 122.472 140.766 83.680  1.00 12.85 ? 102  THR C CG2 1 
ATOM   8388  N N   . ALA C 1 124 ? 120.221 139.922 86.513  1.00 10.75 ? 103  ALA C N   1 
ATOM   8389  C CA  . ALA C 1 124 ? 119.511 140.862 87.369  1.00 10.75 ? 103  ALA C CA  1 
ATOM   8390  C C   . ALA C 1 124 ? 120.061 140.825 88.786  1.00 10.75 ? 103  ALA C C   1 
ATOM   8391  O O   . ALA C 1 124 ? 120.326 141.870 89.392  1.00 10.75 ? 103  ALA C O   1 
ATOM   8392  C CB  . ALA C 1 124 ? 118.016 140.552 87.360  1.00 10.75 ? 103  ALA C CB  1 
ATOM   8393  N N   . GLU C 1 125 ? 120.276 139.623 89.321  1.00 12.74 ? 104  GLU C N   1 
ATOM   8394  C CA  . GLU C 1 125 ? 120.774 139.517 90.687  1.00 12.74 ? 104  GLU C CA  1 
ATOM   8395  C C   . GLU C 1 125 ? 122.212 140.012 90.800  1.00 12.74 ? 104  GLU C C   1 
ATOM   8396  O O   . GLU C 1 125 ? 122.589 140.608 91.816  1.00 12.74 ? 104  GLU C O   1 
ATOM   8397  C CB  . GLU C 1 125 ? 120.660 138.077 91.179  1.00 12.74 ? 104  GLU C CB  1 
ATOM   8398  C CG  . GLU C 1 125 ? 120.825 137.933 92.677  1.00 12.74 ? 104  GLU C CG  1 
ATOM   8399  C CD  . GLU C 1 125 ? 119.859 138.809 93.450  1.00 12.74 ? 104  GLU C CD  1 
ATOM   8400  O OE1 . GLU C 1 125 ? 120.150 140.007 93.642  1.00 12.74 ? 104  GLU C OE1 1 
ATOM   8401  O OE2 . GLU C 1 125 ? 118.798 138.302 93.859  1.00 12.74 ? 104  GLU C OE2 1 
ATOM   8402  N N   . THR C 1 126 ? 123.026 139.781 89.769  1.00 14.16 ? 105  THR C N   1 
ATOM   8403  C CA  . THR C 1 126 ? 124.398 140.277 89.781  1.00 14.16 ? 105  THR C CA  1 
ATOM   8404  C C   . THR C 1 126 ? 124.437 141.798 89.744  1.00 14.16 ? 105  THR C C   1 
ATOM   8405  O O   . THR C 1 126 ? 125.141 142.428 90.539  1.00 14.16 ? 105  THR C O   1 
ATOM   8406  C CB  . THR C 1 126 ? 125.174 139.698 88.605  1.00 14.16 ? 105  THR C CB  1 
ATOM   8407  O OG1 . THR C 1 126 ? 125.401 138.303 88.827  1.00 14.16 ? 105  THR C OG1 1 
ATOM   8408  C CG2 . THR C 1 126 ? 126.501 140.407 88.452  1.00 14.16 ? 105  THR C CG2 1 
ATOM   8409  N N   . TRP C 1 127 ? 123.685 142.407 88.826  1.00 17.26 ? 106  TRP C N   1 
ATOM   8410  C CA  . TRP C 1 127 ? 123.642 143.862 88.748  1.00 17.26 ? 106  TRP C CA  1 
ATOM   8411  C C   . TRP C 1 127 ? 123.120 144.461 90.042  1.00 17.26 ? 106  TRP C C   1 
ATOM   8412  O O   . TRP C 1 127 ? 123.618 145.492 90.505  1.00 17.26 ? 106  TRP C O   1 
ATOM   8413  C CB  . TRP C 1 127 ? 122.761 144.300 87.582  1.00 17.26 ? 106  TRP C CB  1 
ATOM   8414  C CG  . TRP C 1 127 ? 123.491 144.460 86.303  1.00 17.26 ? 106  TRP C CG  1 
ATOM   8415  C CD1 . TRP C 1 127 ? 123.892 143.469 85.460  1.00 17.26 ? 106  TRP C CD1 1 
ATOM   8416  C CD2 . TRP C 1 127 ? 123.912 145.689 85.708  1.00 17.26 ? 106  TRP C CD2 1 
ATOM   8417  N NE1 . TRP C 1 127 ? 124.536 144.004 84.375  1.00 17.26 ? 106  TRP C NE1 1 
ATOM   8418  C CE2 . TRP C 1 127 ? 124.564 145.367 84.505  1.00 17.26 ? 106  TRP C CE2 1 
ATOM   8419  C CE3 . TRP C 1 127 ? 123.803 147.031 86.077  1.00 17.26 ? 106  TRP C CE3 1 
ATOM   8420  C CZ2 . TRP C 1 127 ? 125.103 146.337 83.669  1.00 17.26 ? 106  TRP C CZ2 1 
ATOM   8421  C CZ3 . TRP C 1 127 ? 124.337 147.989 85.249  1.00 17.26 ? 106  TRP C CZ3 1 
ATOM   8422  C CH2 . TRP C 1 127 ? 124.979 147.640 84.058  1.00 17.26 ? 106  TRP C CH2 1 
ATOM   8423  N N   . ASP C 1 128 ? 122.115 143.825 90.640  1.00 15.35 ? 107  ASP C N   1 
ATOM   8424  C CA  . ASP C 1 128 ? 121.453 144.382 91.807  1.00 15.35 ? 107  ASP C CA  1 
ATOM   8425  C C   . ASP C 1 128 ? 122.253 144.211 93.090  1.00 15.35 ? 107  ASP C C   1 
ATOM   8426  O O   . ASP C 1 128 ? 122.172 145.067 93.976  1.00 15.35 ? 107  ASP C O   1 
ATOM   8427  C CB  . ASP C 1 128 ? 120.084 143.732 91.948  1.00 15.35 ? 107  ASP C CB  1 
ATOM   8428  C CG  . ASP C 1 128 ? 119.259 144.354 93.026  1.00 15.35 ? 107  ASP C CG  1 
ATOM   8429  O OD1 . ASP C 1 128 ? 119.005 145.572 92.958  1.00 15.35 ? 107  ASP C OD1 1 
ATOM   8430  O OD2 . ASP C 1 128 ? 118.844 143.611 93.933  1.00 15.35 ? 107  ASP C OD2 1 
ATOM   8431  N N   . ASN C 1 129 ? 123.020 143.127 93.221  1.00 13.83 ? 108  ASN C N   1 
ATOM   8432  C CA  . ASN C 1 129 ? 123.678 142.805 94.479  1.00 13.83 ? 108  ASN C CA  1 
ATOM   8433  C C   . ASN C 1 129 ? 125.197 142.844 94.400  1.00 13.83 ? 108  ASN C C   1 
ATOM   8434  O O   . ASN C 1 129 ? 125.850 142.949 95.443  1.00 13.83 ? 108  ASN C O   1 
ATOM   8435  C CB  . ASN C 1 129 ? 123.218 141.417 94.963  1.00 13.83 ? 108  ASN C CB  1 
ATOM   8436  C CG  . ASN C 1 129 ? 123.614 141.119 96.398  1.00 13.83 ? 108  ASN C CG  1 
ATOM   8437  O OD1 . ASN C 1 129 ? 124.789 140.965 96.718  1.00 13.83 ? 108  ASN C OD1 1 
ATOM   8438  N ND2 . ASN C 1 129 ? 122.622 141.022 97.269  1.00 13.83 ? 108  ASN C ND2 1 
ATOM   8439  N N   . GLY C 1 130 ? 125.778 142.805 93.207  1.00 13.80 ? 109  GLY C N   1 
ATOM   8440  C CA  . GLY C 1 130 ? 127.216 142.823 93.073  1.00 13.80 ? 109  GLY C CA  1 
ATOM   8441  C C   . GLY C 1 130 ? 127.886 141.480 93.220  1.00 13.80 ? 109  GLY C C   1 
ATOM   8442  O O   . GLY C 1 130 ? 129.119 141.417 93.190  1.00 13.80 ? 109  GLY C O   1 
ATOM   8443  N N   . LYS C 1 131 ? 127.122 140.408 93.385  1.00 13.57 ? 110  LYS C N   1 
ATOM   8444  C CA  . LYS C 1 131 ? 127.694 139.079 93.427  1.00 13.57 ? 110  LYS C CA  1 
ATOM   8445  C C   . LYS C 1 131 ? 128.273 138.725 92.063  1.00 13.57 ? 110  LYS C C   1 
ATOM   8446  O O   . LYS C 1 131 ? 127.873 139.289 91.045  1.00 13.57 ? 110  LYS C O   1 
ATOM   8447  C CB  . LYS C 1 131 ? 126.632 138.063 93.824  1.00 13.57 ? 110  LYS C CB  1 
ATOM   8448  C CG  . LYS C 1 131 ? 126.034 138.307 95.182  1.00 13.57 ? 110  LYS C CG  1 
ATOM   8449  C CD  . LYS C 1 131 ? 124.562 138.025 95.141  1.00 13.57 ? 110  LYS C CD  1 
ATOM   8450  C CE  . LYS C 1 131 ? 124.301 136.544 95.261  1.00 13.57 ? 110  LYS C CE  1 
ATOM   8451  N NZ  . LYS C 1 131 ? 123.041 136.301 95.992  1.00 13.57 ? 110  LYS C NZ  1 
ATOM   8452  N N   . PRO C 1 132 ? 129.231 137.805 92.018  1.00 15.42 ? 111  PRO C N   1 
ATOM   8453  C CA  . PRO C 1 132 ? 129.818 137.429 90.731  1.00 15.42 ? 111  PRO C CA  1 
ATOM   8454  C C   . PRO C 1 132 ? 128.785 136.810 89.807  1.00 15.42 ? 111  PRO C C   1 
ATOM   8455  O O   . PRO C 1 132 ? 127.812 136.198 90.247  1.00 15.42 ? 111  PRO C O   1 
ATOM   8456  C CB  . PRO C 1 132 ? 130.897 136.415 91.117  1.00 15.42 ? 111  PRO C CB  1 
ATOM   8457  C CG  . PRO C 1 132 ? 131.184 136.684 92.537  1.00 15.42 ? 111  PRO C CG  1 
ATOM   8458  C CD  . PRO C 1 132 ? 129.903 137.136 93.142  1.00 15.42 ? 111  PRO C CD  1 
ATOM   8459  N N   . ILE C 1 133 ? 129.000 136.993 88.504  1.00 16.31 ? 112  ILE C N   1 
ATOM   8460  C CA  . ILE C 1 133 ? 128.162 136.318 87.522  1.00 16.31 ? 112  ILE C CA  1 
ATOM   8461  C C   . ILE C 1 133 ? 128.516 134.843 87.416  1.00 16.31 ? 112  ILE C C   1 
ATOM   8462  O O   . ILE C 1 133 ? 127.679 134.041 86.989  1.00 16.31 ? 112  ILE C O   1 
ATOM   8463  C CB  . ILE C 1 133 ? 128.277 137.003 86.152  1.00 16.31 ? 112  ILE C CB  1 
ATOM   8464  C CG1 . ILE C 1 133 ? 127.045 136.710 85.304  1.00 16.31 ? 112  ILE C CG1 1 
ATOM   8465  C CG2 . ILE C 1 133 ? 129.523 136.541 85.420  1.00 16.31 ? 112  ILE C CG2 1 
ATOM   8466  C CD1 . ILE C 1 133 ? 125.745 137.062 85.963  1.00 16.31 ? 112  ILE C CD1 1 
ATOM   8467  N N   . ARG C 1 134 ? 129.736 134.464 87.792  1.00 19.23 ? 113  ARG C N   1 
ATOM   8468  C CA  . ARG C 1 134 ? 130.081 133.052 87.876  1.00 19.23 ? 113  ARG C CA  1 
ATOM   8469  C C   . ARG C 1 134 ? 129.309 132.373 88.999  1.00 19.23 ? 113  ARG C C   1 
ATOM   8470  O O   . ARG C 1 134 ? 128.887 131.219 88.867  1.00 19.23 ? 113  ARG C O   1 
ATOM   8471  C CB  . ARG C 1 134 ? 131.586 132.902 88.091  1.00 19.23 ? 113  ARG C CB  1 
ATOM   8472  C CG  . ARG C 1 134 ? 132.035 131.482 88.335  1.00 19.23 ? 113  ARG C CG  1 
ATOM   8473  C CD  . ARG C 1 134 ? 133.216 131.439 89.276  1.00 19.23 ? 113  ARG C CD  1 
ATOM   8474  N NE  . ARG C 1 134 ? 132.810 131.812 90.628  1.00 19.23 ? 113  ARG C NE  1 
ATOM   8475  C CZ  . ARG C 1 134 ? 133.567 131.655 91.708  1.00 19.23 ? 113  ARG C CZ  1 
ATOM   8476  N NH1 . ARG C 1 134 ? 134.767 131.106 91.600  1.00 19.23 ? 113  ARG C NH1 1 
ATOM   8477  N NH2 . ARG C 1 134 ? 133.113 132.026 92.898  1.00 19.23 ? 113  ARG C NH2 1 
ATOM   8478  N N   . GLU C 1 135 ? 129.110 133.080 90.104  1.00 17.60 ? 114  GLU C N   1 
ATOM   8479  C CA  . GLU C 1 135 ? 128.479 132.548 91.300  1.00 17.60 ? 114  GLU C CA  1 
ATOM   8480  C C   . GLU C 1 135 ? 126.958 132.592 91.237  1.00 17.60 ? 114  GLU C C   1 
ATOM   8481  O O   . GLU C 1 135 ? 126.299 132.088 92.150  1.00 17.60 ? 114  GLU C O   1 
ATOM   8482  C CB  . GLU C 1 135 ? 128.986 133.324 92.521  1.00 17.60 ? 114  GLU C CB  1 
ATOM   8483  C CG  . GLU C 1 135 ? 128.668 132.710 93.867  1.00 17.60 ? 114  GLU C CG  1 
ATOM   8484  C CD  . GLU C 1 135 ? 127.576 133.461 94.597  1.00 17.60 ? 114  GLU C CD  1 
ATOM   8485  O OE1 . GLU C 1 135 ? 127.113 134.492 94.071  1.00 17.60 ? 114  GLU C OE1 1 
ATOM   8486  O OE2 . GLU C 1 135 ? 127.182 133.023 95.698  1.00 17.60 ? 114  GLU C OE2 1 
ATOM   8487  N N   . THR C 1 136 ? 126.382 133.164 90.184  1.00 14.67 ? 115  THR C N   1 
ATOM   8488  C CA  . THR C 1 136 ? 124.932 133.254 90.053  1.00 14.67 ? 115  THR C CA  1 
ATOM   8489  C C   . THR C 1 136 ? 124.335 132.243 89.090  1.00 14.67 ? 115  THR C C   1 
ATOM   8490  O O   . THR C 1 136 ? 123.272 131.694 89.377  1.00 14.67 ? 115  THR C O   1 
ATOM   8491  C CB  . THR C 1 136 ? 124.517 134.664 89.626  1.00 14.67 ? 115  THR C CB  1 
ATOM   8492  O OG1 . THR C 1 136 ? 125.289 135.074 88.491  1.00 14.67 ? 115  THR C OG1 1 
ATOM   8493  C CG2 . THR C 1 136 ? 124.708 135.645 90.767  1.00 14.67 ? 115  THR C CG2 1 
ATOM   8494  N N   . MET C 1 137 ? 124.968 131.973 87.953  1.00 14.15 ? 116  MET C N   1 
ATOM   8495  C CA  . MET C 1 137 ? 124.477 130.900 87.098  1.00 14.15 ? 116  MET C CA  1 
ATOM   8496  C C   . MET C 1 137 ? 125.001 129.535 87.508  1.00 14.15 ? 116  MET C C   1 
ATOM   8497  O O   . MET C 1 137 ? 124.946 128.602 86.700  1.00 14.15 ? 116  MET C O   1 
ATOM   8498  C CB  . MET C 1 137 ? 124.838 131.142 85.630  1.00 14.15 ? 116  MET C CB  1 
ATOM   8499  C CG  . MET C 1 137 ? 123.965 132.146 84.918  1.00 14.15 ? 116  MET C CG  1 
ATOM   8500  S SD  . MET C 1 137 ? 124.787 132.808 83.466  1.00 14.15 ? 116  MET C SD  1 
ATOM   8501  C CE  . MET C 1 137 ? 126.238 133.529 84.210  1.00 14.15 ? 116  MET C CE  1 
ATOM   8502  N N   . ALA C 1 138 ? 125.519 129.393 88.724  1.00 13.16 ? 117  ALA C N   1 
ATOM   8503  C CA  . ALA C 1 138 ? 126.066 128.113 89.146  1.00 13.16 ? 117  ALA C CA  1 
ATOM   8504  C C   . ALA C 1 138 ? 125.527 127.685 90.504  1.00 13.16 ? 117  ALA C C   1 
ATOM   8505  O O   . ALA C 1 138 ? 125.400 126.487 90.771  1.00 13.16 ? 117  ALA C O   1 
ATOM   8506  C CB  . ALA C 1 138 ? 127.593 128.176 89.181  1.00 13.16 ? 117  ALA C CB  1 
ATOM   8507  N N   . ALA C 1 139 ? 125.204 128.642 91.368  1.00 11.40 ? 118  ALA C N   1 
ATOM   8508  C CA  . ALA C 1 139 ? 124.863 128.316 92.745  1.00 11.40 ? 118  ALA C CA  1 
ATOM   8509  C C   . ALA C 1 139 ? 123.627 129.011 93.284  1.00 11.40 ? 118  ALA C C   1 
ATOM   8510  O O   . ALA C 1 139 ? 123.147 128.613 94.351  1.00 11.40 ? 118  ALA C O   1 
ATOM   8511  C CB  . ALA C 1 139 ? 126.043 128.634 93.675  1.00 11.40 ? 118  ALA C CB  1 
ATOM   8512  N N   . ASP C 1 140 ? 123.098 130.031 92.612  1.00 11.80 ? 119  ASP C N   1 
ATOM   8513  C CA  . ASP C 1 140 ? 121.952 130.773 93.125  1.00 11.80 ? 119  ASP C CA  1 
ATOM   8514  C C   . ASP C 1 140 ? 120.676 130.433 92.366  1.00 11.80 ? 119  ASP C C   1 
ATOM   8515  O O   . ASP C 1 140 ? 119.688 129.984 92.959  1.00 11.80 ? 119  ASP C O   1 
ATOM   8516  C CB  . ASP C 1 140 ? 122.228 132.279 93.050  1.00 11.80 ? 119  ASP C CB  1 
ATOM   8517  C CG  . ASP C 1 140 ? 123.544 132.656 93.677  1.00 11.80 ? 119  ASP C CG  1 
ATOM   8518  O OD1 . ASP C 1 140 ? 124.035 131.889 94.529  1.00 11.80 ? 119  ASP C OD1 1 
ATOM   8519  O OD2 . ASP C 1 140 ? 124.090 133.718 93.320  1.00 11.80 ? 119  ASP C OD2 1 
ATOM   8520  N N   . LEU C 1 141 ? 120.678 130.641 91.052  1.00 8.50  ? 120  LEU C N   1 
ATOM   8521  C CA  . LEU C 1 141 ? 119.509 130.269 90.259  1.00 8.50  ? 120  LEU C CA  1 
ATOM   8522  C C   . LEU C 1 141 ? 119.264 128.768 90.287  1.00 8.50  ? 120  LEU C C   1 
ATOM   8523  O O   . LEU C 1 141 ? 118.213 128.351 90.802  1.00 8.50  ? 120  LEU C O   1 
ATOM   8524  C CB  . LEU C 1 141 ? 119.634 130.835 88.842  1.00 8.50  ? 120  LEU C CB  1 
ATOM   8525  C CG  . LEU C 1 141 ? 119.205 132.280 88.610  1.00 8.50  ? 120  LEU C CG  1 
ATOM   8526  C CD1 . LEU C 1 141 ? 117.722 132.378 88.881  1.00 8.50  ? 120  LEU C CD1 1 
ATOM   8527  C CD2 . LEU C 1 141 ? 119.963 133.267 89.480  1.00 8.50  ? 120  LEU C CD2 1 
ATOM   8528  N N   . PRO C 1 142 ? 120.196 127.905 89.849  1.00 7.11  ? 121  PRO C N   1 
ATOM   8529  C CA  . PRO C 1 142 ? 119.897 126.466 89.874  1.00 7.11  ? 121  PRO C CA  1 
ATOM   8530  C C   . PRO C 1 142 ? 119.407 125.985 91.228  1.00 7.11  ? 121  PRO C C   1 
ATOM   8531  O O   . PRO C 1 142 ? 118.510 125.139 91.291  1.00 7.11  ? 121  PRO C O   1 
ATOM   8532  C CB  . PRO C 1 142 ? 121.238 125.837 89.485  1.00 7.11  ? 121  PRO C CB  1 
ATOM   8533  C CG  . PRO C 1 142 ? 121.859 126.844 88.616  1.00 7.11  ? 121  PRO C CG  1 
ATOM   8534  C CD  . PRO C 1 142 ? 121.524 128.153 89.260  1.00 7.11  ? 121  PRO C CD  1 
ATOM   8535  N N   . LEU C 1 143 ? 119.928 126.551 92.314  1.00 5.78  ? 122  LEU C N   1 
ATOM   8536  C CA  . LEU C 1 143 ? 119.394 126.237 93.632  1.00 5.78  ? 122  LEU C CA  1 
ATOM   8537  C C   . LEU C 1 143 ? 117.956 126.716 93.786  1.00 5.78  ? 122  LEU C C   1 
ATOM   8538  O O   . LEU C 1 143 ? 117.138 126.031 94.405  1.00 5.78  ? 122  LEU C O   1 
ATOM   8539  C CB  . LEU C 1 143 ? 120.283 126.835 94.716  1.00 5.78  ? 122  LEU C CB  1 
ATOM   8540  C CG  . LEU C 1 143 ? 121.302 125.878 95.331  1.00 5.78  ? 122  LEU C CG  1 
ATOM   8541  C CD1 . LEU C 1 143 ? 122.383 125.501 94.340  1.00 5.78  ? 122  LEU C CD1 1 
ATOM   8542  C CD2 . LEU C 1 143 ? 121.904 126.479 96.590  1.00 5.78  ? 122  LEU C CD2 1 
ATOM   8543  N N   . ALA C 1 144 ? 117.617 127.879 93.224  1.00 5.20  ? 123  ALA C N   1 
ATOM   8544  C CA  . ALA C 1 144 ? 116.247 128.379 93.353  1.00 5.20  ? 123  ALA C CA  1 
ATOM   8545  C C   . ALA C 1 144 ? 115.258 127.519 92.567  1.00 5.20  ? 123  ALA C C   1 
ATOM   8546  O O   . ALA C 1 144 ? 114.193 127.141 93.080  1.00 5.20  ? 123  ALA C O   1 
ATOM   8547  C CB  . ALA C 1 144 ? 116.181 129.834 92.894  1.00 5.20  ? 123  ALA C CB  1 
ATOM   8548  N N   . ILE C 1 145 ? 115.592 127.211 91.315  1.00 3.97  ? 124  ILE C N   1 
ATOM   8549  C CA  . ILE C 1 145 ? 114.748 126.333 90.505  1.00 3.97  ? 124  ILE C CA  1 
ATOM   8550  C C   . ILE C 1 145 ? 114.616 124.963 91.158  1.00 3.97  ? 124  ILE C C   1 
ATOM   8551  O O   . ILE C 1 145 ? 113.524 124.381 91.200  1.00 3.97  ? 124  ILE C O   1 
ATOM   8552  C CB  . ILE C 1 145 ? 115.282 126.221 89.065  1.00 3.97  ? 124  ILE C CB  1 
ATOM   8553  C CG1 . ILE C 1 145 ? 115.188 127.556 88.328  1.00 3.97  ? 124  ILE C CG1 1 
ATOM   8554  C CG2 . ILE C 1 145 ? 114.536 125.151 88.299  1.00 3.97  ? 124  ILE C CG2 1 
ATOM   8555  C CD1 . ILE C 1 145 ? 116.374 128.422 88.435  1.00 3.97  ? 124  ILE C CD1 1 
ATOM   8556  N N   . ASP C 1 146 ? 115.723 124.419 91.670  1.00 3.84  ? 125  ASP C N   1 
ATOM   8557  C CA  . ASP C 1 146 ? 115.650 123.115 92.315  1.00 3.84  ? 125  ASP C CA  1 
ATOM   8558  C C   . ASP C 1 146 ? 114.837 123.169 93.596  1.00 3.84  ? 125  ASP C C   1 
ATOM   8559  O O   . ASP C 1 146 ? 114.187 122.188 93.946  1.00 3.84  ? 125  ASP C O   1 
ATOM   8560  C CB  . ASP C 1 146 ? 117.049 122.583 92.599  1.00 3.84  ? 125  ASP C CB  1 
ATOM   8561  C CG  . ASP C 1 146 ? 117.105 121.076 92.581  1.00 3.84  ? 125  ASP C CG  1 
ATOM   8562  O OD1 . ASP C 1 146 ? 116.320 120.464 91.830  1.00 3.84  ? 125  ASP C OD1 1 
ATOM   8563  O OD2 . ASP C 1 146 ? 117.932 120.502 93.319  1.00 3.84  ? 125  ASP C OD2 1 
ATOM   8564  N N   . HIS C 1 147 ? 114.845 124.296 94.297  1.00 4.13  ? 126  HIS C N   1 
ATOM   8565  C CA  . HIS C 1 147 ? 113.982 124.438 95.460  1.00 4.13  ? 126  HIS C CA  1 
ATOM   8566  C C   . HIS C 1 147 ? 112.516 124.423 95.059  1.00 4.13  ? 126  HIS C C   1 
ATOM   8567  O O   . HIS C 1 147 ? 111.687 123.792 95.728  1.00 4.13  ? 126  HIS C O   1 
ATOM   8568  C CB  . HIS C 1 147 ? 114.331 125.726 96.198  1.00 4.13  ? 126  HIS C CB  1 
ATOM   8569  C CG  . HIS C 1 147 ? 114.152 125.641 97.677  1.00 4.13  ? 126  HIS C CG  1 
ATOM   8570  N ND1 . HIS C 1 147 ? 115.035 124.970 98.493  1.00 4.13  ? 126  HIS C ND1 1 
ATOM   8571  C CD2 . HIS C 1 147 ? 113.210 126.168 98.492  1.00 4.13  ? 126  HIS C CD2 1 
ATOM   8572  C CE1 . HIS C 1 147 ? 114.635 125.073 99.747  1.00 4.13  ? 126  HIS C CE1 1 
ATOM   8573  N NE2 . HIS C 1 147 ? 113.533 125.799 99.774  1.00 4.13  ? 126  HIS C NE2 1 
ATOM   8574  N N   . PHE C 1 148 ? 112.177 125.108 93.968  1.00 3.79  ? 127  PHE C N   1 
ATOM   8575  C CA  . PHE C 1 148 ? 110.797 125.084 93.491  1.00 3.79  ? 127  PHE C CA  1 
ATOM   8576  C C   . PHE C 1 148 ? 110.365 123.669 93.131  1.00 3.79  ? 127  PHE C C   1 
ATOM   8577  O O   . PHE C 1 148 ? 109.304 123.199 93.563  1.00 3.79  ? 127  PHE C O   1 
ATOM   8578  C CB  . PHE C 1 148 ? 110.633 126.018 92.293  1.00 3.79  ? 127  PHE C CB  1 
ATOM   8579  C CG  . PHE C 1 148 ? 110.194 127.390 92.673  1.00 3.79  ? 127  PHE C CG  1 
ATOM   8580  C CD1 . PHE C 1 148 ? 108.978 127.584 93.289  1.00 3.79  ? 127  PHE C CD1 1 
ATOM   8581  C CD2 . PHE C 1 148 ? 111.004 128.478 92.447  1.00 3.79  ? 127  PHE C CD2 1 
ATOM   8582  C CE1 . PHE C 1 148 ? 108.573 128.836 93.657  1.00 3.79  ? 127  PHE C CE1 1 
ATOM   8583  C CE2 . PHE C 1 148 ? 110.602 129.728 92.811  1.00 3.79  ? 127  PHE C CE2 1 
ATOM   8584  C CZ  . PHE C 1 148 ? 109.385 129.908 93.419  1.00 3.79  ? 127  PHE C CZ  1 
ATOM   8585  N N   . ARG C 1 149 ? 111.191 122.966 92.356  1.00 2.34  ? 128  ARG C N   1 
ATOM   8586  C CA  . ARG C 1 149 ? 110.865 121.596 91.979  1.00 2.34  ? 128  ARG C CA  1 
ATOM   8587  C C   . ARG C 1 149 ? 110.774 120.695 93.201  1.00 2.34  ? 128  ARG C C   1 
ATOM   8588  O O   . ARG C 1 149 ? 109.873 119.856 93.302  1.00 2.34  ? 128  ARG C O   1 
ATOM   8589  C CB  . ARG C 1 149 ? 111.905 121.067 91.003  1.00 2.34  ? 128  ARG C CB  1 
ATOM   8590  C CG  . ARG C 1 149 ? 111.647 121.474 89.589  1.00 2.34  ? 128  ARG C CG  1 
ATOM   8591  C CD  . ARG C 1 149 ? 112.895 121.357 88.770  1.00 2.34  ? 128  ARG C CD  1 
ATOM   8592  N NE  . ARG C 1 149 ? 112.671 121.754 87.388  1.00 2.34  ? 128  ARG C NE  1 
ATOM   8593  C CZ  . ARG C 1 149 ? 113.644 122.077 86.548  1.00 2.34  ? 128  ARG C CZ  1 
ATOM   8594  N NH1 . ARG C 1 149 ? 114.901 122.055 86.959  1.00 2.34  ? 128  ARG C NH1 1 
ATOM   8595  N NH2 . ARG C 1 149 ? 113.360 122.430 85.305  1.00 2.34  ? 128  ARG C NH2 1 
ATOM   8596  N N   . TYR C 1 150 ? 111.692 120.867 94.147  1.00 2.42  ? 129  TYR C N   1 
ATOM   8597  C CA  . TYR C 1 150 ? 111.710 120.044 95.345  1.00 2.42  ? 129  TYR C CA  1 
ATOM   8598  C C   . TYR C 1 150 ? 110.446 120.210 96.170  1.00 2.42  ? 129  TYR C C   1 
ATOM   8599  O O   . TYR C 1 150 ? 109.853 119.224 96.614  1.00 2.42  ? 129  TYR C O   1 
ATOM   8600  C CB  . TYR C 1 150 ? 112.943 120.384 96.173  1.00 2.42  ? 129  TYR C CB  1 
ATOM   8601  C CG  . TYR C 1 150 ? 112.959 119.664 97.476  1.00 2.42  ? 129  TYR C CG  1 
ATOM   8602  C CD1 . TYR C 1 150 ? 113.371 118.355 97.546  1.00 2.42  ? 129  TYR C CD1 1 
ATOM   8603  C CD2 . TYR C 1 150 ? 112.591 120.304 98.644  1.00 2.42  ? 129  TYR C CD2 1 
ATOM   8604  C CE1 . TYR C 1 150 ? 113.366 117.692 98.720  1.00 2.42  ? 129  TYR C CE1 1 
ATOM   8605  C CE2 . TYR C 1 150 ? 112.605 119.650 99.832  1.00 2.42  ? 129  TYR C CE2 1 
ATOM   8606  C CZ  . TYR C 1 150 ? 112.997 118.341 99.867  1.00 2.42  ? 129  TYR C CZ  1 
ATOM   8607  O OH  . TYR C 1 150 ? 113.017 117.666 101.055 1.00 2.42  ? 129  TYR C OH  1 
ATOM   8608  N N   . PHE C 1 151 ? 110.020 121.443 96.403  1.00 2.30  ? 130  PHE C N   1 
ATOM   8609  C CA  . PHE C 1 151 ? 108.817 121.612 97.202  1.00 2.30  ? 130  PHE C CA  1 
ATOM   8610  C C   . PHE C 1 151 ? 107.555 121.317 96.413  1.00 2.30  ? 130  PHE C C   1 
ATOM   8611  O O   . PHE C 1 151 ? 106.502 121.098 97.017  1.00 2.30  ? 130  PHE C O   1 
ATOM   8612  C CB  . PHE C 1 151 ? 108.772 123.009 97.807  1.00 2.30  ? 130  PHE C CB  1 
ATOM   8613  C CG  . PHE C 1 151 ? 109.495 123.104 99.104  1.00 2.30  ? 130  PHE C CG  1 
ATOM   8614  C CD1 . PHE C 1 151 ? 108.903 122.654 100.265 1.00 2.30  ? 130  PHE C CD1 1 
ATOM   8615  C CD2 . PHE C 1 151 ? 110.775 123.605 99.165  1.00 2.30  ? 130  PHE C CD2 1 
ATOM   8616  C CE1 . PHE C 1 151 ? 109.566 122.720 101.466 1.00 2.30  ? 130  PHE C CE1 1 
ATOM   8617  C CE2 . PHE C 1 151 ? 111.439 123.669 100.365 1.00 2.30  ? 130  PHE C CE2 1 
ATOM   8618  C CZ  . PHE C 1 151 ? 110.834 123.226 101.513 1.00 2.30  ? 130  PHE C CZ  1 
ATOM   8619  N N   . ALA C 1 152 ? 107.634 121.303 95.083  1.00 1.90  ? 131  ALA C N   1 
ATOM   8620  C CA  . ALA C 1 152 ? 106.572 120.669 94.317  1.00 1.90  ? 131  ALA C CA  1 
ATOM   8621  C C   . ALA C 1 152 ? 106.564 119.167 94.545  1.00 1.90  ? 131  ALA C C   1 
ATOM   8622  O O   . ALA C 1 152 ? 105.511 118.532 94.464  1.00 1.90  ? 131  ALA C O   1 
ATOM   8623  C CB  . ALA C 1 152 ? 106.732 120.979 92.833  1.00 1.90  ? 131  ALA C CB  1 
ATOM   8624  N N   . GLY C 1 153 ? 107.730 118.585 94.829  1.00 1.92  ? 132  GLY C N   1 
ATOM   8625  C CA  . GLY C 1 153 ? 107.805 117.157 95.060  1.00 1.92  ? 132  GLY C CA  1 
ATOM   8626  C C   . GLY C 1 153 ? 107.455 116.717 96.463  1.00 1.92  ? 132  GLY C C   1 
ATOM   8627  O O   . GLY C 1 153 ? 107.008 115.587 96.662  1.00 1.92  ? 132  GLY C O   1 
ATOM   8628  N N   . VAL C 1 154 ? 107.666 117.581 97.454  1.00 1.43  ? 133  VAL C N   1 
ATOM   8629  C CA  . VAL C 1 154 ? 107.318 117.238 98.827  1.00 1.43  ? 133  VAL C CA  1 
ATOM   8630  C C   . VAL C 1 154 ? 105.827 117.375 99.080  1.00 1.43  ? 133  VAL C C   1 
ATOM   8631  O O   . VAL C 1 154 ? 105.287 116.702 99.964  1.00 1.43  ? 133  VAL C O   1 
ATOM   8632  C CB  . VAL C 1 154 ? 108.121 118.116 99.800  1.00 1.43  ? 133  VAL C CB  1 
ATOM   8633  C CG1 . VAL C 1 154 ? 107.734 117.841 101.237 1.00 1.43  ? 133  VAL C CG1 1 
ATOM   8634  C CG2 . VAL C 1 154 ? 109.586 117.878 99.606  1.00 1.43  ? 133  VAL C CG2 1 
ATOM   8635  N N   . LEU C 1 155 ? 105.139 118.222 98.320  1.00 1.44  ? 134  LEU C N   1 
ATOM   8636  C CA  . LEU C 1 155 ? 103.698 118.351 98.470  1.00 1.44  ? 134  LEU C CA  1 
ATOM   8637  C C   . LEU C 1 155 ? 102.969 117.149 97.890  1.00 1.44  ? 134  LEU C C   1 
ATOM   8638  O O   . LEU C 1 155 ? 101.930 116.744 98.419  1.00 1.44  ? 134  LEU C O   1 
ATOM   8639  C CB  . LEU C 1 155 ? 103.223 119.641 97.806  1.00 1.44  ? 134  LEU C CB  1 
ATOM   8640  C CG  . LEU C 1 155 ? 101.745 119.995 97.928  1.00 1.44  ? 134  LEU C CG  1 
ATOM   8641  C CD1 . LEU C 1 155 ? 101.406 120.432 99.338  1.00 1.44  ? 134  LEU C CD1 1 
ATOM   8642  C CD2 . LEU C 1 155 ? 101.398 121.074 96.937  1.00 1.44  ? 134  LEU C CD2 1 
ATOM   8643  N N   . ARG C 1 156 ? 103.497 116.573 96.809  1.00 1.08  ? 135  ARG C N   1 
ATOM   8644  C CA  . ARG C 1 156 ? 102.910 115.360 96.256  1.00 1.08  ? 135  ARG C CA  1 
ATOM   8645  C C   . ARG C 1 156 ? 103.009 114.203 97.238  1.00 1.08  ? 135  ARG C C   1 
ATOM   8646  O O   . ARG C 1 156 ? 102.049 113.446 97.412  1.00 1.08  ? 135  ARG C O   1 
ATOM   8647  C CB  . ARG C 1 156 ? 103.597 115.002 94.942  1.00 1.08  ? 135  ARG C CB  1 
ATOM   8648  C CG  . ARG C 1 156 ? 103.479 116.067 93.886  1.00 1.08  ? 135  ARG C CG  1 
ATOM   8649  C CD  . ARG C 1 156 ? 102.036 116.269 93.496  1.00 1.08  ? 135  ARG C CD  1 
ATOM   8650  N NE  . ARG C 1 156 ? 101.694 115.507 92.303  1.00 1.08  ? 135  ARG C NE  1 
ATOM   8651  C CZ  . ARG C 1 156 ? 100.676 114.662 92.229  1.00 1.08  ? 135  ARG C CZ  1 
ATOM   8652  N NH1 . ARG C 1 156 ? 99.895  114.469 93.281  1.00 1.08  ? 135  ARG C NH1 1 
ATOM   8653  N NH2 . ARG C 1 156 ? 100.440 114.013 91.102  1.00 1.08  ? 135  ARG C NH2 1 
ATOM   8654  N N   . ALA C 1 157 ? 104.156 114.053 97.896  1.00 1.28  ? 136  ALA C N   1 
ATOM   8655  C CA  . ALA C 1 157 ? 104.373 112.960 98.834  1.00 1.28  ? 136  ALA C CA  1 
ATOM   8656  C C   . ALA C 1 157 ? 103.782 113.222 100.210 1.00 1.28  ? 136  ALA C C   1 
ATOM   8657  O O   . ALA C 1 157 ? 103.795 112.321 101.051 1.00 1.28  ? 136  ALA C O   1 
ATOM   8658  C CB  . ALA C 1 157 ? 105.870 112.680 98.975  1.00 1.28  ? 136  ALA C CB  1 
ATOM   8659  N N   . GLN C 1 158 ? 103.269 114.416 100.461 1.00 1.59  ? 137  GLN C N   1 
ATOM   8660  C CA  . GLN C 1 158 ? 102.808 114.764 101.793 1.00 1.59  ? 137  GLN C CA  1 
ATOM   8661  C C   . GLN C 1 158 ? 101.548 113.997 102.161 1.00 1.59  ? 137  GLN C C   1 
ATOM   8662  O O   . GLN C 1 158 ? 100.700 113.702 101.317 1.00 1.59  ? 137  GLN C O   1 
ATOM   8663  C CB  . GLN C 1 158 ? 102.535 116.257 101.882 1.00 1.59  ? 137  GLN C CB  1 
ATOM   8664  C CG  . GLN C 1 158 ? 102.413 116.757 103.281 1.00 1.59  ? 137  GLN C CG  1 
ATOM   8665  C CD  . GLN C 1 158 ? 101.818 118.124 103.331 1.00 1.59  ? 137  GLN C CD  1 
ATOM   8666  O OE1 . GLN C 1 158 ? 101.992 118.846 104.303 1.00 1.59  ? 137  GLN C OE1 1 
ATOM   8667  N NE2 . GLN C 1 158 ? 101.099 118.495 102.281 1.00 1.59  ? 137  GLN C NE2 1 
ATOM   8668  N N   . GLU C 1 159 ? 101.423 113.695 103.448 1.00 2.57  ? 138  GLU C N   1 
ATOM   8669  C CA  . GLU C 1 159 ? 100.291 112.955 103.973 1.00 2.57  ? 138  GLU C CA  1 
ATOM   8670  C C   . GLU C 1 159 ? 99.940  113.477 105.352 1.00 2.57  ? 138  GLU C C   1 
ATOM   8671  O O   . GLU C 1 159 ? 100.795 113.994 106.070 1.00 2.57  ? 138  GLU C O   1 
ATOM   8672  C CB  . GLU C 1 159 ? 100.593 111.465 104.066 1.00 2.57  ? 138  GLU C CB  1 
ATOM   8673  C CG  . GLU C 1 159 ? 100.320 110.720 102.800 1.00 2.57  ? 138  GLU C CG  1 
ATOM   8674  C CD  . GLU C 1 159 ? 100.836 109.315 102.841 1.00 2.57  ? 138  GLU C CD  1 
ATOM   8675  O OE1 . GLU C 1 159 ? 101.797 109.064 103.597 1.00 2.57  ? 138  GLU C OE1 1 
ATOM   8676  O OE2 . GLU C 1 159 ? 100.281 108.459 102.121 1.00 2.57  ? 138  GLU C OE2 1 
ATOM   8677  N N   . GLY C 1 160 ? 98.675  113.340 105.711 1.00 2.17  ? 139  GLY C N   1 
ATOM   8678  C CA  . GLY C 1 160 ? 98.254  113.487 107.085 1.00 2.17  ? 139  GLY C CA  1 
ATOM   8679  C C   . GLY C 1 160 ? 98.417  112.159 107.789 1.00 2.17  ? 139  GLY C C   1 
ATOM   8680  O O   . GLY C 1 160 ? 99.171  111.288 107.350 1.00 2.17  ? 139  GLY C O   1 
ATOM   8681  N N   . SER C 1 161 ? 97.691  111.986 108.886 1.00 2.43  ? 140  SER C N   1 
ATOM   8682  C CA  . SER C 1 161 ? 97.876  110.760 109.646 1.00 2.43  ? 140  SER C CA  1 
ATOM   8683  C C   . SER C 1 161 ? 96.558  110.281 110.229 1.00 2.43  ? 140  SER C C   1 
ATOM   8684  O O   . SER C 1 161 ? 95.726  111.074 110.665 1.00 2.43  ? 140  SER C O   1 
ATOM   8685  C CB  . SER C 1 161 ? 98.904  110.948 110.766 1.00 2.43  ? 140  SER C CB  1 
ATOM   8686  O OG  . SER C 1 161 ? 98.289  111.427 111.945 1.00 2.43  ? 140  SER C OG  1 
ATOM   8687  N N   . ILE C 1 162 ? 96.386  108.966 110.244 1.00 2.56  ? 141  ILE C N   1 
ATOM   8688  C CA  . ILE C 1 162 ? 95.242  108.321 110.869 1.00 2.56  ? 141  ILE C CA  1 
ATOM   8689  C C   . ILE C 1 162 ? 95.736  107.577 112.096 1.00 2.56  ? 141  ILE C C   1 
ATOM   8690  O O   . ILE C 1 162 ? 96.699  106.808 112.018 1.00 2.56  ? 141  ILE C O   1 
ATOM   8691  C CB  . ILE C 1 162 ? 94.530  107.360 109.903 1.00 2.56  ? 141  ILE C CB  1 
ATOM   8692  C CG1 . ILE C 1 162 ? 94.229  108.046 108.581 1.00 2.56  ? 141  ILE C CG1 1 
ATOM   8693  C CG2 . ILE C 1 162 ? 93.252  106.871 110.500 1.00 2.56  ? 141  ILE C CG2 1 
ATOM   8694  C CD1 . ILE C 1 162 ? 93.678  107.116 107.560 1.00 2.56  ? 141  ILE C CD1 1 
ATOM   8695  N N   . SER C 1 163 ? 95.086  107.803 113.223 1.00 4.38  ? 142  SER C N   1 
ATOM   8696  C CA  . SER C 1 163 ? 95.345  107.048 114.439 1.00 4.38  ? 142  SER C CA  1 
ATOM   8697  C C   . SER C 1 163 ? 94.086  106.262 114.777 1.00 4.38  ? 142  SER C C   1 
ATOM   8698  O O   . SER C 1 163 ? 93.046  106.849 115.098 1.00 4.38  ? 142  SER C O   1 
ATOM   8699  C CB  . SER C 1 163 ? 95.751  107.966 115.586 1.00 4.38  ? 142  SER C CB  1 
ATOM   8700  O OG  . SER C 1 163 ? 94.611  108.516 116.206 1.00 4.38  ? 142  SER C OG  1 
ATOM   8701  N N   . GLN C 1 164 ? 94.182  104.939 114.687 1.00 7.32  ? 143  GLN C N   1 
ATOM   8702  C CA  . GLN C 1 164 ? 93.079  104.039 115.009 1.00 7.32  ? 143  GLN C CA  1 
ATOM   8703  C C   . GLN C 1 164 ? 93.044  103.884 116.520 1.00 7.32  ? 143  GLN C C   1 
ATOM   8704  O O   . GLN C 1 164 ? 93.743  103.051 117.094 1.00 7.32  ? 143  GLN C O   1 
ATOM   8705  C CB  . GLN C 1 164 ? 93.276  102.693 114.332 1.00 7.32  ? 143  GLN C CB  1 
ATOM   8706  C CG  . GLN C 1 164 ? 93.287  102.738 112.825 1.00 7.32  ? 143  GLN C CG  1 
ATOM   8707  C CD  . GLN C 1 164 ? 93.525  101.375 112.226 1.00 7.32  ? 143  GLN C CD  1 
ATOM   8708  O OE1 . GLN C 1 164 ? 93.563  101.219 111.008 1.00 7.32  ? 143  GLN C OE1 1 
ATOM   8709  N NE2 . GLN C 1 164 ? 93.626  100.369 113.075 1.00 7.32  ? 143  GLN C NE2 1 
ATOM   8710  N N   . ILE C 1 165 ? 92.226  104.705 117.177 1.00 9.41  ? 144  ILE C N   1 
ATOM   8711  C CA  . ILE C 1 165 ? 92.139  104.653 118.633 1.00 9.41  ? 144  ILE C CA  1 
ATOM   8712  C C   . ILE C 1 165 ? 91.653  103.283 119.084 1.00 9.41  ? 144  ILE C C   1 
ATOM   8713  O O   . ILE C 1 165 ? 92.224  102.664 119.989 1.00 9.41  ? 144  ILE C O   1 
ATOM   8714  C CB  . ILE C 1 165 ? 91.222  105.773 119.152 1.00 9.41  ? 144  ILE C CB  1 
ATOM   8715  C CG1 . ILE C 1 165 ? 91.656  107.124 118.587 1.00 9.41  ? 144  ILE C CG1 1 
ATOM   8716  C CG2 . ILE C 1 165 ? 91.203  105.789 120.671 1.00 9.41  ? 144  ILE C CG2 1 
ATOM   8717  C CD1 . ILE C 1 165 ? 93.101  107.444 118.832 1.00 9.41  ? 144  ILE C CD1 1 
ATOM   8718  N N   . ASP C 1 166 ? 90.593  102.793 118.456 1.00 12.10 ? 145  ASP C N   1 
ATOM   8719  C CA  . ASP C 1 166 ? 89.996  101.507 118.775 1.00 12.10 ? 145  ASP C CA  1 
ATOM   8720  C C   . ASP C 1 166 ? 89.188  101.070 117.558 1.00 12.10 ? 145  ASP C C   1 
ATOM   8721  O O   . ASP C 1 166 ? 89.354  101.621 116.464 1.00 12.10 ? 145  ASP C O   1 
ATOM   8722  C CB  . ASP C 1 166 ? 89.163  101.605 120.063 1.00 12.10 ? 145  ASP C CB  1 
ATOM   8723  C CG  . ASP C 1 166 ? 88.154  102.731 120.022 1.00 12.10 ? 145  ASP C CG  1 
ATOM   8724  O OD1 . ASP C 1 166 ? 87.774  103.154 118.914 1.00 12.10 ? 145  ASP C OD1 1 
ATOM   8725  O OD2 . ASP C 1 166 ? 87.746  103.205 121.103 1.00 12.10 ? 145  ASP C OD2 1 
ATOM   8726  N N   . ASP C 1 167 ? 88.321  100.075 117.741 1.00 13.47 ? 146  ASP C N   1 
ATOM   8727  C CA  . ASP C 1 167 ? 87.465  99.646  116.646 1.00 13.47 ? 146  ASP C CA  1 
ATOM   8728  C C   . ASP C 1 167 ? 86.429  100.698 116.268 1.00 13.47 ? 146  ASP C C   1 
ATOM   8729  O O   . ASP C 1 167 ? 85.955  100.697 115.128 1.00 13.47 ? 146  ASP C O   1 
ATOM   8730  C CB  . ASP C 1 167 ? 86.768  98.336  117.007 1.00 13.47 ? 146  ASP C CB  1 
ATOM   8731  C CG  . ASP C 1 167 ? 86.248  97.598  115.790 1.00 13.47 ? 146  ASP C CG  1 
ATOM   8732  O OD1 . ASP C 1 167 ? 87.063  96.978  115.075 1.00 13.47 ? 146  ASP C OD1 1 
ATOM   8733  O OD2 . ASP C 1 167 ? 85.022  97.639  115.548 1.00 13.47 ? 146  ASP C OD2 1 
ATOM   8734  N N   . ASP C 1 168 ? 86.078  101.599 117.184 1.00 12.02 ? 147  ASP C N   1 
ATOM   8735  C CA  . ASP C 1 168 ? 84.999  102.550 116.954 1.00 12.02 ? 147  ASP C CA  1 
ATOM   8736  C C   . ASP C 1 168 ? 85.462  103.972 116.686 1.00 12.02 ? 147  ASP C C   1 
ATOM   8737  O O   . ASP C 1 168 ? 84.761  104.709 115.994 1.00 12.02 ? 147  ASP C O   1 
ATOM   8738  C CB  . ASP C 1 168 ? 84.049  102.575 118.155 1.00 12.02 ? 147  ASP C CB  1 
ATOM   8739  C CG  . ASP C 1 168 ? 83.701  101.189 118.647 1.00 12.02 ? 147  ASP C CG  1 
ATOM   8740  O OD1 . ASP C 1 168 ? 83.103  100.409 117.876 1.00 12.02 ? 147  ASP C OD1 1 
ATOM   8741  O OD2 . ASP C 1 168 ? 84.029  100.880 119.810 1.00 12.02 ? 147  ASP C OD2 1 
ATOM   8742  N N   . THR C 1 169 ? 86.612  104.379 117.213 1.00 8.96  ? 148  THR C N   1 
ATOM   8743  C CA  . THR C 1 169 ? 87.037  105.771 117.185 1.00 8.96  ? 148  THR C CA  1 
ATOM   8744  C C   . THR C 1 169 ? 88.298  105.903 116.349 1.00 8.96  ? 148  THR C C   1 
ATOM   8745  O O   . THR C 1 169 ? 89.241  105.125 116.513 1.00 8.96  ? 148  THR C O   1 
ATOM   8746  C CB  . THR C 1 169 ? 87.277  106.291 118.606 1.00 8.96  ? 148  THR C CB  1 
ATOM   8747  O OG1 . THR C 1 169 ? 86.093  106.098 119.390 1.00 8.96  ? 148  THR C OG1 1 
ATOM   8748  C CG2 . THR C 1 169 ? 87.611  107.764 118.588 1.00 8.96  ? 148  THR C CG2 1 
ATOM   8749  N N   . VAL C 1 170 ? 88.307  106.885 115.452 1.00 5.96  ? 149  VAL C N   1 
ATOM   8750  C CA  . VAL C 1 170 ? 89.409  107.125 114.532 1.00 5.96  ? 149  VAL C CA  1 
ATOM   8751  C C   . VAL C 1 170 ? 89.750  108.606 114.570 1.00 5.96  ? 149  VAL C C   1 
ATOM   8752  O O   . VAL C 1 170 ? 88.854  109.453 114.580 1.00 5.96  ? 149  VAL C O   1 
ATOM   8753  C CB  . VAL C 1 170 ? 89.046  106.693 113.097 1.00 5.96  ? 149  VAL C CB  1 
ATOM   8754  C CG1 . VAL C 1 170 ? 90.220  106.868 112.182 1.00 5.96  ? 149  VAL C CG1 1 
ATOM   8755  C CG2 . VAL C 1 170 ? 88.589  105.262 113.078 1.00 5.96  ? 149  VAL C CG2 1 
ATOM   8756  N N   . ALA C 1 171 ? 91.038  108.930 114.578 1.00 4.09  ? 150  ALA C N   1 
ATOM   8757  C CA  . ALA C 1 171 ? 91.476  110.318 114.550 1.00 4.09  ? 150  ALA C CA  1 
ATOM   8758  C C   . ALA C 1 171 ? 92.192  110.599 113.239 1.00 4.09  ? 150  ALA C C   1 
ATOM   8759  O O   . ALA C 1 171 ? 93.113  109.872 112.863 1.00 4.09  ? 150  ALA C O   1 
ATOM   8760  C CB  . ALA C 1 171 ? 92.385  110.631 115.737 1.00 4.09  ? 150  ALA C CB  1 
ATOM   8761  N N   . TYR C 1 172 ? 91.764  111.649 112.550 1.00 3.58  ? 151  TYR C N   1 
ATOM   8762  C CA  . TYR C 1 172 ? 92.319  112.057 111.271 1.00 3.58  ? 151  TYR C CA  1 
ATOM   8763  C C   . TYR C 1 172 ? 93.059  113.373 111.445 1.00 3.58  ? 151  TYR C C   1 
ATOM   8764  O O   . TYR C 1 172 ? 92.585  114.268 112.147 1.00 3.58  ? 151  TYR C O   1 
ATOM   8765  C CB  . TYR C 1 172 ? 91.216  112.232 110.230 1.00 3.58  ? 151  TYR C CB  1 
ATOM   8766  C CG  . TYR C 1 172 ? 90.321  111.033 110.045 1.00 3.58  ? 151  TYR C CG  1 
ATOM   8767  C CD1 . TYR C 1 172 ? 90.778  109.896 109.409 1.00 3.58  ? 151  TYR C CD1 1 
ATOM   8768  C CD2 . TYR C 1 172 ? 89.013  111.049 110.493 1.00 3.58  ? 151  TYR C CD2 1 
ATOM   8769  C CE1 . TYR C 1 172 ? 89.967  108.811 109.233 1.00 3.58  ? 151  TYR C CE1 1 
ATOM   8770  C CE2 . TYR C 1 172 ? 88.194  109.966 110.321 1.00 3.58  ? 151  TYR C CE2 1 
ATOM   8771  C CZ  . TYR C 1 172 ? 88.677  108.848 109.689 1.00 3.58  ? 151  TYR C CZ  1 
ATOM   8772  O OH  . TYR C 1 172 ? 87.864  107.754 109.510 1.00 3.58  ? 151  TYR C OH  1 
ATOM   8773  N N   . HIS C 1 173 ? 94.215  113.493 110.804 1.00 3.10  ? 152  HIS C N   1 
ATOM   8774  C CA  . HIS C 1 173 ? 95.031  114.698 110.880 1.00 3.10  ? 152  HIS C CA  1 
ATOM   8775  C C   . HIS C 1 173 ? 95.349  115.151 109.465 1.00 3.10  ? 152  HIS C C   1 
ATOM   8776  O O   . HIS C 1 173 ? 96.161  114.522 108.777 1.00 3.10  ? 152  HIS C O   1 
ATOM   8777  C CB  . HIS C 1 173 ? 96.312  114.449 111.675 1.00 3.10  ? 152  HIS C CB  1 
ATOM   8778  C CG  . HIS C 1 173 ? 96.087  113.769 112.989 1.00 3.10  ? 152  HIS C CG  1 
ATOM   8779  N ND1 . HIS C 1 173 ? 96.447  112.461 113.221 1.00 3.10  ? 152  HIS C ND1 1 
ATOM   8780  C CD2 . HIS C 1 173 ? 95.539  114.218 114.141 1.00 3.10  ? 152  HIS C CD2 1 
ATOM   8781  C CE1 . HIS C 1 173 ? 96.130  112.132 114.459 1.00 3.10  ? 152  HIS C CE1 1 
ATOM   8782  N NE2 . HIS C 1 173 ? 95.576  113.180 115.039 1.00 3.10  ? 152  HIS C NE2 1 
ATOM   8783  N N   . PHE C 1 174 ? 94.706  116.235 109.042 1.00 2.89  ? 153  PHE C N   1 
ATOM   8784  C CA  . PHE C 1 174 ? 94.912  116.865 107.748 1.00 2.89  ? 153  PHE C CA  1 
ATOM   8785  C C   . PHE C 1 174 ? 95.862  118.045 107.878 1.00 2.89  ? 153  PHE C C   1 
ATOM   8786  O O   . PHE C 1 174 ? 96.005  118.642 108.944 1.00 2.89  ? 153  PHE C O   1 
ATOM   8787  C CB  . PHE C 1 174 ? 93.597  117.370 107.153 1.00 2.89  ? 153  PHE C CB  1 
ATOM   8788  C CG  . PHE C 1 174 ? 92.499  116.358 107.122 1.00 2.89  ? 153  PHE C CG  1 
ATOM   8789  C CD1 . PHE C 1 174 ? 91.663  116.194 108.206 1.00 2.89  ? 153  PHE C CD1 1 
ATOM   8790  C CD2 . PHE C 1 174 ? 92.270  115.604 105.989 1.00 2.89  ? 153  PHE C CD2 1 
ATOM   8791  C CE1 . PHE C 1 174 ? 90.643  115.283 108.169 1.00 2.89  ? 153  PHE C CE1 1 
ATOM   8792  C CE2 . PHE C 1 174 ? 91.248  114.696 105.948 1.00 2.89  ? 153  PHE C CE2 1 
ATOM   8793  C CZ  . PHE C 1 174 ? 90.435  114.532 107.041 1.00 2.89  ? 153  PHE C CZ  1 
ATOM   8794  N N   . HIS C 1 175 ? 96.480  118.401 106.760 1.00 2.75  ? 154  HIS C N   1 
ATOM   8795  C CA  . HIS C 1 175 ? 97.346  119.567 106.664 1.00 2.75  ? 154  HIS C CA  1 
ATOM   8796  C C   . HIS C 1 175 ? 96.605  120.668 105.919 1.00 2.75  ? 154  HIS C C   1 
ATOM   8797  O O   . HIS C 1 175 ? 96.215  120.481 104.763 1.00 2.75  ? 154  HIS C O   1 
ATOM   8798  C CB  . HIS C 1 175 ? 98.641  119.220 105.939 1.00 2.75  ? 154  HIS C CB  1 
ATOM   8799  C CG  . HIS C 1 175 ? 99.489  118.221 106.657 1.00 2.75  ? 154  HIS C CG  1 
ATOM   8800  N ND1 . HIS C 1 175 ? 99.883  118.383 107.965 1.00 2.75  ? 154  HIS C ND1 1 
ATOM   8801  C CD2 . HIS C 1 175 ? 100.038 117.057 106.241 1.00 2.75  ? 154  HIS C CD2 1 
ATOM   8802  C CE1 . HIS C 1 175 ? 100.630 117.357 108.328 1.00 2.75  ? 154  HIS C CE1 1 
ATOM   8803  N NE2 . HIS C 1 175 ? 100.738 116.537 107.301 1.00 2.75  ? 154  HIS C NE2 1 
ATOM   8804  N N   . GLU C 1 176 ? 96.419  121.815 106.578 1.00 3.81  ? 155  GLU C N   1 
ATOM   8805  C CA  . GLU C 1 176 ? 95.758  122.989 106.042 1.00 3.81  ? 155  GLU C CA  1 
ATOM   8806  C C   . GLU C 1 176 ? 96.759  124.122 105.847 1.00 3.81  ? 155  GLU C C   1 
ATOM   8807  O O   . GLU C 1 176 ? 97.756  124.201 106.568 1.00 3.81  ? 155  GLU C O   1 
ATOM   8808  C CB  . GLU C 1 176 ? 94.649  123.465 106.985 1.00 3.81  ? 155  GLU C CB  1 
ATOM   8809  C CG  . GLU C 1 176 ? 93.599  122.424 107.295 1.00 3.81  ? 155  GLU C CG  1 
ATOM   8810  C CD  . GLU C 1 176 ? 92.230  123.039 107.502 1.00 3.81  ? 155  GLU C CD  1 
ATOM   8811  O OE1 . GLU C 1 176 ? 91.220  122.401 107.136 1.00 3.81  ? 155  GLU C OE1 1 
ATOM   8812  O OE2 . GLU C 1 176 ? 92.165  124.167 108.030 1.00 3.81  ? 155  GLU C OE2 1 
ATOM   8813  N N   . PRO C 1 177 ? 96.529  125.019 104.893 1.00 2.57  ? 156  PRO C N   1 
ATOM   8814  C CA  . PRO C 1 177 ? 97.401  126.188 104.762 1.00 2.57  ? 156  PRO C CA  1 
ATOM   8815  C C   . PRO C 1 177 ? 97.220  127.129 105.940 1.00 2.57  ? 156  PRO C C   1 
ATOM   8816  O O   . PRO C 1 177 ? 96.207  127.106 106.640 1.00 2.57  ? 156  PRO C O   1 
ATOM   8817  C CB  . PRO C 1 177 ? 96.936  126.841 103.457 1.00 2.57  ? 156  PRO C CB  1 
ATOM   8818  C CG  . PRO C 1 177 ? 96.075  125.829 102.796 1.00 2.57  ? 156  PRO C CG  1 
ATOM   8819  C CD  . PRO C 1 177 ? 95.464  125.030 103.882 1.00 2.57  ? 156  PRO C CD  1 
ATOM   8820  N N   . LEU C 1 178 ? 98.235  127.964 106.164 1.00 3.75  ? 157  LEU C N   1 
ATOM   8821  C CA  . LEU C 1 178 ? 98.142  128.947 107.237 1.00 3.75  ? 157  LEU C CA  1 
ATOM   8822  C C   . LEU C 1 178 ? 97.236  130.110 106.867 1.00 3.75  ? 157  LEU C C   1 
ATOM   8823  O O   . LEU C 1 178 ? 96.591  130.691 107.745 1.00 3.75  ? 157  LEU C O   1 
ATOM   8824  C CB  . LEU C 1 178 ? 99.525  129.478 107.600 1.00 3.75  ? 157  LEU C CB  1 
ATOM   8825  C CG  . LEU C 1 178 ? 100.349 128.712 108.627 1.00 3.75  ? 157  LEU C CG  1 
ATOM   8826  C CD1 . LEU C 1 178 ? 101.684 129.394 108.801 1.00 3.75  ? 157  LEU C CD1 1 
ATOM   8827  C CD2 . LEU C 1 178 ? 99.622  128.621 109.948 1.00 3.75  ? 157  LEU C CD2 1 
ATOM   8828  N N   . GLY C 1 179 ? 97.168  130.454 105.585 1.00 4.32  ? 158  GLY C N   1 
ATOM   8829  C CA  . GLY C 1 179 ? 96.452  131.635 105.158 1.00 4.32  ? 158  GLY C CA  1 
ATOM   8830  C C   . GLY C 1 179 ? 97.359  132.595 104.422 1.00 4.32  ? 158  GLY C C   1 
ATOM   8831  O O   . GLY C 1 179 ? 97.804  132.304 103.309 1.00 4.32  ? 158  GLY C O   1 
ATOM   8832  N N   . VAL C 1 180 ? 97.641  133.743 105.032 1.00 7.10  ? 159  VAL C N   1 
ATOM   8833  C CA  . VAL C 1 180 ? 98.550  134.738 104.477 1.00 7.10  ? 159  VAL C CA  1 
ATOM   8834  C C   . VAL C 1 180 ? 99.814  134.769 105.322 1.00 7.10  ? 159  VAL C C   1 
ATOM   8835  O O   . VAL C 1 180 ? 99.748  134.739 106.556 1.00 7.10  ? 159  VAL C O   1 
ATOM   8836  C CB  . VAL C 1 180 ? 97.901  136.133 104.421 1.00 7.10  ? 159  VAL C CB  1 
ATOM   8837  C CG1 . VAL C 1 180 ? 98.821  137.109 103.723 1.00 7.10  ? 159  VAL C CG1 1 
ATOM   8838  C CG2 . VAL C 1 180 ? 96.566  136.068 103.715 1.00 7.10  ? 159  VAL C CG2 1 
ATOM   8839  N N   . VAL C 1 181 ? 100.963 134.817 104.658 1.00 7.26  ? 160  VAL C N   1 
ATOM   8840  C CA  . VAL C 1 181 ? 102.257 134.910 105.321 1.00 7.26  ? 160  VAL C CA  1 
ATOM   8841  C C   . VAL C 1 181 ? 103.095 135.982 104.633 1.00 7.26  ? 160  VAL C C   1 
ATOM   8842  O O   . VAL C 1 181 ? 103.189 136.018 103.403 1.00 7.26  ? 160  VAL C O   1 
ATOM   8843  C CB  . VAL C 1 181 ? 102.989 133.548 105.345 1.00 7.26  ? 160  VAL C CB  1 
ATOM   8844  C CG1 . VAL C 1 181 ? 102.190 132.535 106.135 1.00 7.26  ? 160  VAL C CG1 1 
ATOM   8845  C CG2 . VAL C 1 181 ? 103.185 133.018 103.941 1.00 7.26  ? 160  VAL C CG2 1 
ATOM   8846  N N   . GLY C 1 182 ? 103.683 136.869 105.430 1.00 8.76  ? 161  GLY C N   1 
ATOM   8847  C CA  . GLY C 1 182 ? 104.512 137.943 104.913 1.00 8.76  ? 161  GLY C CA  1 
ATOM   8848  C C   . GLY C 1 182 ? 105.983 137.639 105.125 1.00 8.76  ? 161  GLY C C   1 
ATOM   8849  O O   . GLY C 1 182 ? 106.396 137.251 106.219 1.00 8.76  ? 161  GLY C O   1 
ATOM   8850  N N   . GLN C 1 183 ? 106.766 137.823 104.067 1.00 7.80  ? 162  GLN C N   1 
ATOM   8851  C CA  . GLN C 1 183 ? 108.174 137.447 104.052 1.00 7.80  ? 162  GLN C CA  1 
ATOM   8852  C C   . GLN C 1 183 ? 109.041 138.677 103.832 1.00 7.80  ? 162  GLN C C   1 
ATOM   8853  O O   . GLN C 1 183 ? 108.761 139.489 102.947 1.00 7.80  ? 162  GLN C O   1 
ATOM   8854  C CB  . GLN C 1 183 ? 108.449 136.408 102.964 1.00 7.80  ? 162  GLN C CB  1 
ATOM   8855  C CG  . GLN C 1 183 ? 107.387 135.333 102.858 1.00 7.80  ? 162  GLN C CG  1 
ATOM   8856  C CD  . GLN C 1 183 ? 107.429 134.369 104.021 1.00 7.80  ? 162  GLN C CD  1 
ATOM   8857  O OE1 . GLN C 1 183 ? 108.457 134.210 104.670 1.00 7.80  ? 162  GLN C OE1 1 
ATOM   8858  N NE2 . GLN C 1 183 ? 106.308 133.724 104.295 1.00 7.80  ? 162  GLN C NE2 1 
ATOM   8859  N N   . ILE C 1 184 ? 110.093 138.804 104.634 1.00 10.07 ? 163  ILE C N   1 
ATOM   8860  C CA  . ILE C 1 184 ? 111.022 139.924 104.560 1.00 10.07 ? 163  ILE C CA  1 
ATOM   8861  C C   . ILE C 1 184 ? 112.353 139.359 104.083 1.00 10.07 ? 163  ILE C C   1 
ATOM   8862  O O   . ILE C 1 184 ? 113.109 138.775 104.866 1.00 10.07 ? 163  ILE C O   1 
ATOM   8863  C CB  . ILE C 1 184 ? 111.161 140.648 105.902 1.00 10.07 ? 163  ILE C CB  1 
ATOM   8864  C CG1 . ILE C 1 184 ? 109.781 141.043 106.422 1.00 10.07 ? 163  ILE C CG1 1 
ATOM   8865  C CG2 . ILE C 1 184 ? 112.031 141.881 105.756 1.00 10.07 ? 163  ILE C CG2 1 
ATOM   8866  C CD1 . ILE C 1 184 ? 109.802 141.769 107.741 1.00 10.07 ? 163  ILE C CD1 1 
ATOM   8867  N N   . ILE C 1 185 ? 112.641 139.532 102.799 1.00 10.70 ? 164  ILE C N   1 
ATOM   8868  C CA  . ILE C 1 185 ? 113.824 138.962 102.161 1.00 10.70 ? 164  ILE C CA  1 
ATOM   8869  C C   . ILE C 1 185 ? 115.065 139.739 102.580 1.00 10.70 ? 164  ILE C C   1 
ATOM   8870  O O   . ILE C 1 185 ? 115.046 140.977 102.582 1.00 10.70 ? 164  ILE C O   1 
ATOM   8871  C CB  . ILE C 1 185 ? 113.666 138.964 100.634 1.00 10.70 ? 164  ILE C CB  1 
ATOM   8872  C CG1 . ILE C 1 185 ? 112.260 138.507 100.260 1.00 10.70 ? 164  ILE C CG1 1 
ATOM   8873  C CG2 . ILE C 1 185 ? 114.700 138.070 99.981  1.00 10.70 ? 164  ILE C CG2 1 
ATOM   8874  C CD1 . ILE C 1 185 ? 111.863 138.864 98.861  1.00 10.70 ? 164  ILE C CD1 1 
ATOM   8875  N N   . PRO C 1 186 ? 116.160 139.072 102.939 1.00 14.01 ? 165  PRO C N   1 
ATOM   8876  C CA  . PRO C 1 186 ? 117.403 139.802 103.206 1.00 14.01 ? 165  PRO C CA  1 
ATOM   8877  C C   . PRO C 1 186 ? 118.055 140.249 101.911 1.00 14.01 ? 165  PRO C C   1 
ATOM   8878  O O   . PRO C 1 186 ? 117.498 140.029 100.833 1.00 14.01 ? 165  PRO C O   1 
ATOM   8879  C CB  . PRO C 1 186 ? 118.255 138.769 103.947 1.00 14.01 ? 165  PRO C CB  1 
ATOM   8880  C CG  . PRO C 1 186 ? 117.805 137.473 103.382 1.00 14.01 ? 165  PRO C CG  1 
ATOM   8881  C CD  . PRO C 1 186 ? 116.325 137.622 103.138 1.00 14.01 ? 165  PRO C CD  1 
ATOM   8882  N N   . TRP C 1 187 ? 119.225 140.871 101.987 1.00 12.75 ? 166  TRP C N   1 
ATOM   8883  C CA  . TRP C 1 187 ? 119.939 141.295 100.793 1.00 12.75 ? 166  TRP C CA  1 
ATOM   8884  C C   . TRP C 1 187 ? 121.087 140.359 100.435 1.00 12.75 ? 166  TRP C C   1 
ATOM   8885  O O   . TRP C 1 187 ? 121.824 140.634 99.484  1.00 12.75 ? 166  TRP C O   1 
ATOM   8886  C CB  . TRP C 1 187 ? 120.454 142.724 100.970 1.00 12.75 ? 166  TRP C CB  1 
ATOM   8887  C CG  . TRP C 1 187 ? 121.048 142.956 102.305 1.00 12.75 ? 166  TRP C CG  1 
ATOM   8888  C CD1 . TRP C 1 187 ? 120.433 143.488 103.395 1.00 12.75 ? 166  TRP C CD1 1 
ATOM   8889  C CD2 . TRP C 1 187 ? 122.380 142.641 102.707 1.00 12.75 ? 166  TRP C CD2 1 
ATOM   8890  N NE1 . TRP C 1 187 ? 121.304 143.533 104.454 1.00 12.75 ? 166  TRP C NE1 1 
ATOM   8891  C CE2 . TRP C 1 187 ? 122.508 143.017 104.055 1.00 12.75 ? 166  TRP C CE2 1 
ATOM   8892  C CE3 . TRP C 1 187 ? 123.480 142.080 102.056 1.00 12.75 ? 166  TRP C CE3 1 
ATOM   8893  C CZ2 . TRP C 1 187 ? 123.690 142.850 104.763 1.00 12.75 ? 166  TRP C CZ2 1 
ATOM   8894  C CZ3 . TRP C 1 187 ? 124.647 141.915 102.758 1.00 12.75 ? 166  TRP C CZ3 1 
ATOM   8895  C CH2 . TRP C 1 187 ? 124.746 142.296 104.098 1.00 12.75 ? 166  TRP C CH2 1 
ATOM   8896  N N   . ASN C 1 188 ? 121.236 139.249 101.160 1.00 13.61 ? 167  ASN C N   1 
ATOM   8897  C CA  . ASN C 1 188 ? 122.376 138.362 100.955 1.00 13.61 ? 167  ASN C CA  1 
ATOM   8898  C C   . ASN C 1 188 ? 122.242 137.606 99.639  1.00 13.61 ? 167  ASN C C   1 
ATOM   8899  O O   . ASN C 1 188 ? 123.070 137.750 98.733  1.00 13.61 ? 167  ASN C O   1 
ATOM   8900  C CB  . ASN C 1 188 ? 122.469 137.382 102.123 1.00 13.61 ? 167  ASN C CB  1 
ATOM   8901  C CG  . ASN C 1 188 ? 122.875 138.052 103.414 1.00 13.61 ? 167  ASN C CG  1 
ATOM   8902  O OD1 . ASN C 1 188 ? 123.755 138.909 103.432 1.00 13.61 ? 167  ASN C OD1 1 
ATOM   8903  N ND2 . ASN C 1 188 ? 122.224 137.670 104.506 1.00 13.61 ? 167  ASN C ND2 1 
ATOM   8904  N N   . PHE C 1 189 ? 121.205 136.783 99.527  1.00 10.75 ? 168  PHE C N   1 
ATOM   8905  C CA  . PHE C 1 189 ? 120.767 136.217 98.253  1.00 10.75 ? 168  PHE C CA  1 
ATOM   8906  C C   . PHE C 1 189 ? 119.356 136.728 98.028  1.00 10.75 ? 168  PHE C C   1 
ATOM   8907  O O   . PHE C 1 189 ? 118.390 136.132 98.534  1.00 10.75 ? 168  PHE C O   1 
ATOM   8908  C CB  . PHE C 1 189 ? 120.787 134.689 98.255  1.00 10.75 ? 168  PHE C CB  1 
ATOM   8909  C CG  . PHE C 1 189 ? 122.116 134.083 98.596  1.00 10.75 ? 168  PHE C CG  1 
ATOM   8910  C CD1 . PHE C 1 189 ? 122.492 133.894 99.914  1.00 10.75 ? 168  PHE C CD1 1 
ATOM   8911  C CD2 . PHE C 1 189 ? 122.973 133.662 97.593  1.00 10.75 ? 168  PHE C CD2 1 
ATOM   8912  C CE1 . PHE C 1 189 ? 123.708 133.323 100.225 1.00 10.75 ? 168  PHE C CE1 1 
ATOM   8913  C CE2 . PHE C 1 189 ? 124.187 133.090 97.895  1.00 10.75 ? 168  PHE C CE2 1 
ATOM   8914  C CZ  . PHE C 1 189 ? 124.557 132.919 99.213  1.00 10.75 ? 168  PHE C CZ  1 
ATOM   8915  N N   . PRO C 1 190 ? 119.177 137.827 97.295  1.00 11.20 ? 169  PRO C N   1 
ATOM   8916  C CA  . PRO C 1 190 ? 117.831 138.394 97.135  1.00 11.20 ? 169  PRO C CA  1 
ATOM   8917  C C   . PRO C 1 190 ? 116.924 137.576 96.236  1.00 11.20 ? 169  PRO C C   1 
ATOM   8918  O O   . PRO C 1 190 ? 115.721 137.857 96.183  1.00 11.20 ? 169  PRO C O   1 
ATOM   8919  C CB  . PRO C 1 190 ? 118.105 139.777 96.529  1.00 11.20 ? 169  PRO C CB  1 
ATOM   8920  C CG  . PRO C 1 190 ? 119.558 140.019 96.762  1.00 11.20 ? 169  PRO C CG  1 
ATOM   8921  C CD  . PRO C 1 190 ? 120.211 138.695 96.724  1.00 11.20 ? 169  PRO C CD  1 
ATOM   8922  N N   . LEU C 1 191 ? 117.450 136.583 95.530  1.00 9.23  ? 170  LEU C N   1 
ATOM   8923  C CA  . LEU C 1 191 ? 116.617 135.683 94.748  1.00 9.23  ? 170  LEU C CA  1 
ATOM   8924  C C   . LEU C 1 191 ? 116.643 134.254 95.261  1.00 9.23  ? 170  LEU C C   1 
ATOM   8925  O O   . LEU C 1 191 ? 115.602 133.598 95.282  1.00 9.23  ? 170  LEU C O   1 
ATOM   8926  C CB  . LEU C 1 191 ? 117.041 135.706 93.278  1.00 9.23  ? 170  LEU C CB  1 
ATOM   8927  C CG  . LEU C 1 191 ? 116.069 135.010 92.331  1.00 9.23  ? 170  LEU C CG  1 
ATOM   8928  C CD1 . LEU C 1 191 ? 114.697 135.647 92.436  1.00 9.23  ? 170  LEU C CD1 1 
ATOM   8929  C CD2 . LEU C 1 191 ? 116.578 135.104 90.917  1.00 9.23  ? 170  LEU C CD2 1 
ATOM   8930  N N   . LEU C 1 192 ? 117.801 133.756 95.690  1.00 7.96  ? 171  LEU C N   1 
ATOM   8931  C CA  . LEU C 1 192 ? 117.853 132.413 96.256  1.00 7.96  ? 171  LEU C CA  1 
ATOM   8932  C C   . LEU C 1 192 ? 117.071 132.332 97.562  1.00 7.96  ? 171  LEU C C   1 
ATOM   8933  O O   . LEU C 1 192 ? 116.300 131.393 97.776  1.00 7.96  ? 171  LEU C O   1 
ATOM   8934  C CB  . LEU C 1 192 ? 119.303 131.986 96.466  1.00 7.96  ? 171  LEU C CB  1 
ATOM   8935  C CG  . LEU C 1 192 ? 119.486 130.541 96.921  1.00 7.96  ? 171  LEU C CG  1 
ATOM   8936  C CD1 . LEU C 1 192 ? 118.602 129.626 96.106  1.00 7.96  ? 171  LEU C CD1 1 
ATOM   8937  C CD2 . LEU C 1 192 ? 120.934 130.123 96.805  1.00 7.96  ? 171  LEU C CD2 1 
ATOM   8938  N N   . MET C 1 193 ? 117.250 133.309 98.448  1.00 8.88  ? 172  MET C N   1 
ATOM   8939  C CA  . MET C 1 193 ? 116.543 133.276 99.723  1.00 8.88  ? 172  MET C CA  1 
ATOM   8940  C C   . MET C 1 193 ? 115.070 133.611 99.560  1.00 8.88  ? 172  MET C C   1 
ATOM   8941  O O   . MET C 1 193 ? 114.228 133.066 100.283 1.00 8.88  ? 172  MET C O   1 
ATOM   8942  C CB  . MET C 1 193 ? 117.193 134.238 100.716 1.00 8.88  ? 172  MET C CB  1 
ATOM   8943  C CG  . MET C 1 193 ? 118.216 133.589 101.637 1.00 8.88  ? 172  MET C CG  1 
ATOM   8944  S SD  . MET C 1 193 ? 117.483 132.594 102.950 1.00 8.88  ? 172  MET C SD  1 
ATOM   8945  C CE  . MET C 1 193 ? 116.333 133.759 103.671 1.00 8.88  ? 172  MET C CE  1 
ATOM   8946  N N   . ALA C 1 194 ? 114.741 134.486 98.609  1.00 6.58  ? 173  ALA C N   1 
ATOM   8947  C CA  . ALA C 1 194 ? 113.342 134.777 98.328  1.00 6.58  ? 173  ALA C CA  1 
ATOM   8948  C C   . ALA C 1 194 ? 112.605 133.523 97.888  1.00 6.58  ? 173  ALA C C   1 
ATOM   8949  O O   . ALA C 1 194 ? 111.496 133.252 98.353  1.00 6.58  ? 173  ALA C O   1 
ATOM   8950  C CB  . ALA C 1 194 ? 113.234 135.861 97.260  1.00 6.58  ? 173  ALA C CB  1 
ATOM   8951  N N   . CYS C 1 195 ? 113.219 132.727 97.011  1.00 5.74  ? 174  CYS C N   1 
ATOM   8952  C CA  . CYS C 1 195 ? 112.592 131.478 96.596  1.00 5.74  ? 174  CYS C CA  1 
ATOM   8953  C C   . CYS C 1 195 ? 112.603 130.450 97.720  1.00 5.74  ? 174  CYS C C   1 
ATOM   8954  O O   . CYS C 1 195 ? 111.635 129.700 97.885  1.00 5.74  ? 174  CYS C O   1 
ATOM   8955  C CB  . CYS C 1 195 ? 113.287 130.940 95.352  1.00 5.74  ? 174  CYS C CB  1 
ATOM   8956  S SG  . CYS C 1 195 ? 113.072 132.004 93.915  1.00 5.74  ? 174  CYS C SG  1 
ATOM   8957  N N   . TRP C 1 196 ? 113.676 130.414 98.517  1.00 6.23  ? 175  TRP C N   1 
ATOM   8958  C CA  . TRP C 1 196 ? 113.719 129.504 99.657  1.00 6.23  ? 175  TRP C CA  1 
ATOM   8959  C C   . TRP C 1 196 ? 112.571 129.767 100.616 1.00 6.23  ? 175  TRP C C   1 
ATOM   8960  O O   . TRP C 1 196 ? 112.090 128.844 101.279 1.00 6.23  ? 175  TRP C O   1 
ATOM   8961  C CB  . TRP C 1 196 ? 115.042 129.640 100.415 1.00 6.23  ? 175  TRP C CB  1 
ATOM   8962  C CG  . TRP C 1 196 ? 116.153 128.787 99.898  1.00 6.23  ? 175  TRP C CG  1 
ATOM   8963  C CD1 . TRP C 1 196 ? 116.056 127.790 98.984  1.00 6.23  ? 175  TRP C CD1 1 
ATOM   8964  C CD2 . TRP C 1 196 ? 117.527 128.832 100.297 1.00 6.23  ? 175  TRP C CD2 1 
ATOM   8965  N NE1 . TRP C 1 196 ? 117.286 127.219 98.767  1.00 6.23  ? 175  TRP C NE1 1 
ATOM   8966  C CE2 . TRP C 1 196 ? 118.207 127.844 99.564  1.00 6.23  ? 175  TRP C CE2 1 
ATOM   8967  C CE3 . TRP C 1 196 ? 118.250 129.622 101.193 1.00 6.23  ? 175  TRP C CE3 1 
ATOM   8968  C CZ2 . TRP C 1 196 ? 119.573 127.620 99.702  1.00 6.23  ? 175  TRP C CZ2 1 
ATOM   8969  C CZ3 . TRP C 1 196 ? 119.605 129.400 101.328 1.00 6.23  ? 175  TRP C CZ3 1 
ATOM   8970  C CH2 . TRP C 1 196 ? 120.253 128.408 100.586 1.00 6.23  ? 175  TRP C CH2 1 
ATOM   8971  N N   . LYS C 1 197 ? 112.141 131.020 100.723 1.00 5.13  ? 176  LYS C N   1 
ATOM   8972  C CA  . LYS C 1 197 ? 111.043 131.379 101.607 1.00 5.13  ? 176  LYS C CA  1 
ATOM   8973  C C   . LYS C 1 197 ? 109.682 131.345 100.925 1.00 5.13  ? 176  LYS C C   1 
ATOM   8974  O O   . LYS C 1 197 ? 108.666 131.236 101.615 1.00 5.13  ? 176  LYS C O   1 
ATOM   8975  C CB  . LYS C 1 197 ? 111.286 132.774 102.194 1.00 5.13  ? 176  LYS C CB  1 
ATOM   8976  C CG  . LYS C 1 197 ? 112.530 132.854 103.070 1.00 5.13  ? 176  LYS C CG  1 
ATOM   8977  C CD  . LYS C 1 197 ? 112.740 134.244 103.645 1.00 5.13  ? 176  LYS C CD  1 
ATOM   8978  C CE  . LYS C 1 197 ? 111.549 134.718 104.454 1.00 5.13  ? 176  LYS C CE  1 
ATOM   8979  N NZ  . LYS C 1 197 ? 110.937 133.626 105.259 1.00 5.13  ? 176  LYS C NZ  1 
ATOM   8980  N N   . LEU C 1 198 ? 109.638 131.449 99.597  1.00 4.44  ? 177  LEU C N   1 
ATOM   8981  C CA  . LEU C 1 198 ? 108.371 131.372 98.877  1.00 4.44  ? 177  LEU C CA  1 
ATOM   8982  C C   . LEU C 1 198 ? 107.923 129.937 98.666  1.00 4.44  ? 177  LEU C C   1 
ATOM   8983  O O   . LEU C 1 198 ? 106.820 129.560 99.074  1.00 4.44  ? 177  LEU C O   1 
ATOM   8984  C CB  . LEU C 1 198 ? 108.473 132.081 97.527  1.00 4.44  ? 177  LEU C CB  1 
ATOM   8985  C CG  . LEU C 1 198 ? 108.473 133.594 97.627  1.00 4.44  ? 177  LEU C CG  1 
ATOM   8986  C CD1 . LEU C 1 198 ? 108.703 134.217 96.283  1.00 4.44  ? 177  LEU C CD1 1 
ATOM   8987  C CD2 . LEU C 1 198 ? 107.137 133.985 98.162  1.00 4.44  ? 177  LEU C CD2 1 
ATOM   8988  N N   . ALA C 1 199 ? 108.761 129.129 98.017  1.00 2.72  ? 178  ALA C N   1 
ATOM   8989  C CA  . ALA C 1 199 ? 108.332 127.809 97.561  1.00 2.72  ? 178  ALA C CA  1 
ATOM   8990  C C   . ALA C 1 199 ? 107.642 126.988 98.644  1.00 2.72  ? 178  ALA C C   1 
ATOM   8991  O O   . ALA C 1 199 ? 106.565 126.442 98.368  1.00 2.72  ? 178  ALA C O   1 
ATOM   8992  C CB  . ALA C 1 199 ? 109.532 127.065 96.961  1.00 2.72  ? 178  ALA C CB  1 
ATOM   8993  N N   . PRO C 1 200 ? 108.166 126.864 99.869  1.00 2.55  ? 179  PRO C N   1 
ATOM   8994  C CA  . PRO C 1 200 ? 107.368 126.191 100.907 1.00 2.55  ? 179  PRO C CA  1 
ATOM   8995  C C   . PRO C 1 200 ? 106.042 126.866 101.189 1.00 2.55  ? 179  PRO C C   1 
ATOM   8996  O O   . PRO C 1 200 ? 105.052 126.177 101.449 1.00 2.55  ? 179  PRO C O   1 
ATOM   8997  C CB  . PRO C 1 200 ? 108.284 126.217 102.138 1.00 2.55  ? 179  PRO C CB  1 
ATOM   8998  C CG  . PRO C 1 200 ? 109.409 127.093 101.792 1.00 2.55  ? 179  PRO C CG  1 
ATOM   8999  C CD  . PRO C 1 200 ? 109.548 127.079 100.321 1.00 2.55  ? 179  PRO C CD  1 
ATOM   9000  N N   . ALA C 1 201 ? 105.986 128.197 101.148 1.00 2.64  ? 180  ALA C N   1 
ATOM   9001  C CA  . ALA C 1 201 ? 104.761 128.896 101.518 1.00 2.64  ? 180  ALA C CA  1 
ATOM   9002  C C   . ALA C 1 201 ? 103.703 128.809 100.432 1.00 2.64  ? 180  ALA C C   1 
ATOM   9003  O O   . ALA C 1 201 ? 102.507 128.834 100.735 1.00 2.64  ? 180  ALA C O   1 
ATOM   9004  C CB  . ALA C 1 201 ? 105.063 130.358 101.837 1.00 2.64  ? 180  ALA C CB  1 
ATOM   9005  N N   . ILE C 1 202 ? 104.120 128.712 99.172  1.00 2.28  ? 181  ILE C N   1 
ATOM   9006  C CA  . ILE C 1 202 ? 103.174 128.563 98.074  1.00 2.28  ? 181  ILE C CA  1 
ATOM   9007  C C   . ILE C 1 202 ? 102.783 127.102 97.878  1.00 2.28  ? 181  ILE C C   1 
ATOM   9008  O O   . ILE C 1 202 ? 101.640 126.810 97.512  1.00 2.28  ? 181  ILE C O   1 
ATOM   9009  C CB  . ILE C 1 202 ? 103.769 129.190 96.802  1.00 2.28  ? 181  ILE C CB  1 
ATOM   9010  C CG1 . ILE C 1 202 ? 103.844 130.703 96.968  1.00 2.28  ? 181  ILE C CG1 1 
ATOM   9011  C CG2 . ILE C 1 202 ? 102.975 128.824 95.576  1.00 2.28  ? 181  ILE C CG2 1 
ATOM   9012  C CD1 . ILE C 1 202 ? 104.626 131.396 95.896  1.00 2.28  ? 181  ILE C CD1 1 
ATOM   9013  N N   . ALA C 1 203 ? 103.699 126.165 98.134  1.00 2.00  ? 182  ALA C N   1 
ATOM   9014  C CA  . ALA C 1 203 ? 103.346 124.750 98.089  1.00 2.00  ? 182  ALA C CA  1 
ATOM   9015  C C   . ALA C 1 203 ? 102.281 124.417 99.121  1.00 2.00  ? 182  ALA C C   1 
ATOM   9016  O O   . ALA C 1 203 ? 101.343 123.666 98.838  1.00 2.00  ? 182  ALA C O   1 
ATOM   9017  C CB  . ALA C 1 203 ? 104.584 123.888 98.315  1.00 2.00  ? 182  ALA C CB  1 
ATOM   9018  N N   . ALA C 1 204 ? 102.408 124.959 100.324 1.00 2.32  ? 183  ALA C N   1 
ATOM   9019  C CA  . ALA C 1 204 ? 101.415 124.723 101.357 1.00 2.32  ? 183  ALA C CA  1 
ATOM   9020  C C   . ALA C 1 204 ? 100.097 125.425 101.080 1.00 2.32  ? 183  ALA C C   1 
ATOM   9021  O O   . ALA C 1 204 ? 99.132  125.192 101.811 1.00 2.32  ? 183  ALA C O   1 
ATOM   9022  C CB  . ALA C 1 204 ? 101.963 125.163 102.710 1.00 2.32  ? 183  ALA C CB  1 
ATOM   9023  N N   . GLY C 1 205 ? 100.031 126.281 100.065 1.00 2.48  ? 184  GLY C N   1 
ATOM   9024  C CA  . GLY C 1 205 ? 98.784  126.908 99.691  1.00 2.48  ? 184  GLY C CA  1 
ATOM   9025  C C   . GLY C 1 205 ? 98.525  128.254 100.318 1.00 2.48  ? 184  GLY C C   1 
ATOM   9026  O O   . GLY C 1 205 ? 97.362  128.600 100.551 1.00 2.48  ? 184  GLY C O   1 
ATOM   9027  N N   . ASN C 1 206 ? 99.565  129.030 100.598 1.00 2.91  ? 185  ASN C N   1 
ATOM   9028  C CA  . ASN C 1 206 ? 99.417  130.338 101.210 1.00 2.91  ? 185  ASN C CA  1 
ATOM   9029  C C   . ASN C 1 206 ? 99.644  131.435 100.182 1.00 2.91  ? 185  ASN C C   1 
ATOM   9030  O O   . ASN C 1 206 ? 100.320 131.243 99.170  1.00 2.91  ? 185  ASN C O   1 
ATOM   9031  C CB  . ASN C 1 206 ? 100.396 130.528 102.372 1.00 2.91  ? 185  ASN C CB  1 
ATOM   9032  C CG  . ASN C 1 206 ? 100.391 129.373 103.333 1.00 2.91  ? 185  ASN C CG  1 
ATOM   9033  O OD1 . ASN C 1 206 ? 99.598  129.333 104.269 1.00 2.91  ? 185  ASN C OD1 1 
ATOM   9034  N ND2 . ASN C 1 206 ? 101.291 128.428 103.117 1.00 2.91  ? 185  ASN C ND2 1 
ATOM   9035  N N   . CYS C 1 207 ? 99.064  132.596 100.461 1.00 4.35  ? 186  CYS C N   1 
ATOM   9036  C CA  . CYS C 1 207 ? 99.355  133.816 99.726  1.00 4.35  ? 186  CYS C CA  1 
ATOM   9037  C C   . CYS C 1 207 ? 100.421 134.597 100.479 1.00 4.35  ? 186  CYS C C   1 
ATOM   9038  O O   . CYS C 1 207 ? 100.390 134.677 101.709 1.00 4.35  ? 186  CYS C O   1 
ATOM   9039  C CB  . CYS C 1 207 ? 98.097  134.660 99.549  1.00 4.35  ? 186  CYS C CB  1 
ATOM   9040  S SG  . CYS C 1 207 ? 96.724  133.767 98.801  1.00 4.35  ? 186  CYS C SG  1 
ATOM   9041  N N   . VAL C 1 208 ? 101.369 135.162 99.740  1.00 5.18  ? 187  VAL C N   1 
ATOM   9042  C CA  . VAL C 1 208 ? 102.571 135.747 100.317 1.00 5.18  ? 187  VAL C CA  1 
ATOM   9043  C C   . VAL C 1 208 ? 102.606 137.240 100.030 1.00 5.18  ? 187  VAL C C   1 
ATOM   9044  O O   . VAL C 1 208 ? 102.268 137.680 98.927  1.00 5.18  ? 187  VAL C O   1 
ATOM   9045  C CB  . VAL C 1 208 ? 103.845 135.063 99.779  1.00 5.18  ? 187  VAL C CB  1 
ATOM   9046  C CG1 . VAL C 1 208 ? 103.978 133.672 100.354 1.00 5.18  ? 187  VAL C CG1 1 
ATOM   9047  C CG2 . VAL C 1 208 ? 103.797 134.992 98.277  1.00 5.18  ? 187  VAL C CG2 1 
ATOM   9048  N N   . VAL C 1 209 ? 103.005 138.014 101.032 1.00 6.72  ? 188  VAL C N   1 
ATOM   9049  C CA  . VAL C 1 209 ? 103.307 139.430 100.878 1.00 6.72  ? 188  VAL C CA  1 
ATOM   9050  C C   . VAL C 1 209 ? 104.802 139.586 101.095 1.00 6.72  ? 188  VAL C C   1 
ATOM   9051  O O   . VAL C 1 209 ? 105.311 139.312 102.187 1.00 6.72  ? 188  VAL C O   1 
ATOM   9052  C CB  . VAL C 1 209 ? 102.514 140.300 101.860 1.00 6.72  ? 188  VAL C CB  1 
ATOM   9053  C CG1 . VAL C 1 209 ? 102.730 141.759 101.544 1.00 6.72  ? 188  VAL C CG1 1 
ATOM   9054  C CG2 . VAL C 1 209 ? 101.036 139.953 101.813 1.00 6.72  ? 188  VAL C CG2 1 
ATOM   9055  N N   . LEU C 1 210 ? 105.511 140.022 100.063 1.00 8.23  ? 189  LEU C N   1 
ATOM   9056  C CA  . LEU C 1 210 ? 106.960 140.147 100.108 1.00 8.23  ? 189  LEU C CA  1 
ATOM   9057  C C   . LEU C 1 210 ? 107.372 141.600 100.281 1.00 8.23  ? 189  LEU C C   1 
ATOM   9058  O O   . LEU C 1 210 ? 106.825 142.492 99.628  1.00 8.23  ? 189  LEU C O   1 
ATOM   9059  C CB  . LEU C 1 210 ? 107.594 139.594 98.832  1.00 8.23  ? 189  LEU C CB  1 
ATOM   9060  C CG  . LEU C 1 210 ? 108.152 138.182 98.913  1.00 8.23  ? 189  LEU C CG  1 
ATOM   9061  C CD1 . LEU C 1 210 ? 107.063 137.253 99.372  1.00 8.23  ? 189  LEU C CD1 1 
ATOM   9062  C CD2 . LEU C 1 210 ? 108.679 137.759 97.565  1.00 8.23  ? 189  LEU C CD2 1 
ATOM   9063  N N   . LYS C 1 211 ? 108.342 141.833 101.157 1.00 10.58 ? 190  LYS C N   1 
ATOM   9064  C CA  . LYS C 1 211 ? 109.084 143.092 101.157 1.00 10.58 ? 190  LYS C CA  1 
ATOM   9065  C C   . LYS C 1 211 ? 110.561 142.792 100.967 1.00 10.58 ? 190  LYS C C   1 
ATOM   9066  O O   . LYS C 1 211 ? 111.250 142.417 101.931 1.00 10.58 ? 190  LYS C O   1 
ATOM   9067  C CB  . LYS C 1 211 ? 108.871 143.891 102.437 1.00 10.58 ? 190  LYS C CB  1 
ATOM   9068  C CG  . LYS C 1 211 ? 109.562 145.253 102.367 1.00 10.58 ? 190  LYS C CG  1 
ATOM   9069  C CD  . LYS C 1 211 ? 109.850 145.822 103.736 1.00 10.58 ? 190  LYS C CD  1 
ATOM   9070  C CE  . LYS C 1 211 ? 111.226 145.424 104.229 1.00 10.58 ? 190  LYS C CE  1 
ATOM   9071  N NZ  . LYS C 1 211 ? 111.312 145.465 105.712 1.00 10.58 ? 190  LYS C NZ  1 
ATOM   9072  N N   . PRO C 1 212 ? 111.088 142.919 99.754  1.00 10.01 ? 191  PRO C N   1 
ATOM   9073  C CA  . PRO C 1 212 ? 112.538 142.822 99.571  1.00 10.01 ? 191  PRO C CA  1 
ATOM   9074  C C   . PRO C 1 212 ? 113.262 143.934 100.312 1.00 10.01 ? 191  PRO C C   1 
ATOM   9075  O O   . PRO C 1 212 ? 112.769 145.058 100.420 1.00 10.01 ? 191  PRO C O   1 
ATOM   9076  C CB  . PRO C 1 212 ? 112.711 142.956 98.056  1.00 10.01 ? 191  PRO C CB  1 
ATOM   9077  C CG  . PRO C 1 212 ? 111.387 142.622 97.484  1.00 10.01 ? 191  PRO C CG  1 
ATOM   9078  C CD  . PRO C 1 212 ? 110.375 143.060 98.478  1.00 10.01 ? 191  PRO C CD  1 
ATOM   9079  N N   . ALA C 1 213 ? 114.444 143.610 100.825 1.00 13.29 ? 192  ALA C N   1 
ATOM   9080  C CA  . ALA C 1 213 ? 115.260 144.609 101.498 1.00 13.29 ? 192  ALA C CA  1 
ATOM   9081  C C   . ALA C 1 213 ? 115.715 145.667 100.504 1.00 13.29 ? 192  ALA C C   1 
ATOM   9082  O O   . ALA C 1 213 ? 116.096 145.357 99.372  1.00 13.29 ? 192  ALA C O   1 
ATOM   9083  C CB  . ALA C 1 213 ? 116.469 143.953 102.160 1.00 13.29 ? 192  ALA C CB  1 
ATOM   9084  N N   . GLU C 1 214 ? 115.678 146.928 100.936 1.00 17.13 ? 193  GLU C N   1 
ATOM   9085  C CA  . GLU C 1 214 ? 115.988 148.044 100.052 1.00 17.13 ? 193  GLU C CA  1 
ATOM   9086  C C   . GLU C 1 214 ? 117.446 148.092 99.621  1.00 17.13 ? 193  GLU C C   1 
ATOM   9087  O O   . GLU C 1 214 ? 117.771 148.864 98.714  1.00 17.13 ? 193  GLU C O   1 
ATOM   9088  C CB  . GLU C 1 214 ? 115.607 149.365 100.715 1.00 17.13 ? 193  GLU C CB  1 
ATOM   9089  C CG  . GLU C 1 214 ? 116.379 149.677 101.978 1.00 17.13 ? 193  GLU C CG  1 
ATOM   9090  C CD  . GLU C 1 214 ? 115.708 149.110 103.214 1.00 17.13 ? 193  GLU C CD  1 
ATOM   9091  O OE1 . GLU C 1 214 ? 114.812 148.254 103.065 1.00 17.13 ? 193  GLU C OE1 1 
ATOM   9092  O OE2 . GLU C 1 214 ? 116.074 149.521 104.334 1.00 17.13 ? 193  GLU C OE2 1 
ATOM   9093  N N   . GLN C 1 215 ? 118.330 147.312 100.243 1.00 15.39 ? 194  GLN C N   1 
ATOM   9094  C CA  . GLN C 1 215 ? 119.712 147.274 99.778  1.00 15.39 ? 194  GLN C CA  1 
ATOM   9095  C C   . GLN C 1 215 ? 119.791 146.722 98.365  1.00 15.39 ? 194  GLN C C   1 
ATOM   9096  O O   . GLN C 1 215 ? 120.539 147.237 97.526  1.00 15.39 ? 194  GLN C O   1 
ATOM   9097  C CB  . GLN C 1 215 ? 120.567 146.432 100.720 1.00 15.39 ? 194  GLN C CB  1 
ATOM   9098  C CG  . GLN C 1 215 ? 121.085 147.183 101.918 1.00 15.39 ? 194  GLN C CG  1 
ATOM   9099  C CD  . GLN C 1 215 ? 120.129 147.125 103.084 1.00 15.39 ? 194  GLN C CD  1 
ATOM   9100  O OE1 . GLN C 1 215 ? 118.917 147.031 102.902 1.00 15.39 ? 194  GLN C OE1 1 
ATOM   9101  N NE2 . GLN C 1 215 ? 120.669 147.177 104.293 1.00 15.39 ? 194  GLN C NE2 1 
ATOM   9102  N N   . THR C 1 216 ? 119.026 145.672 98.086  1.00 13.82 ? 195  THR C N   1 
ATOM   9103  C CA  . THR C 1 216 ? 119.056 144.977 96.800  1.00 13.82 ? 195  THR C CA  1 
ATOM   9104  C C   . THR C 1 216 ? 117.636 144.657 96.360  1.00 13.82 ? 195  THR C C   1 
ATOM   9105  O O   . THR C 1 216 ? 117.224 143.492 96.338  1.00 13.82 ? 195  THR C O   1 
ATOM   9106  C CB  . THR C 1 216 ? 119.888 143.699 96.902  1.00 13.82 ? 195  THR C CB  1 
ATOM   9107  O OG1 . THR C 1 216 ? 119.285 142.834 97.869  1.00 13.82 ? 195  THR C OG1 1 
ATOM   9108  C CG2 . THR C 1 216 ? 121.317 144.003 97.314  1.00 13.82 ? 195  THR C CG2 1 
ATOM   9109  N N   . PRO C 1 217 ? 116.854 145.671 95.992  1.00 14.21 ? 196  PRO C N   1 
ATOM   9110  C CA  . PRO C 1 217 ? 115.474 145.400 95.575  1.00 14.21 ? 196  PRO C CA  1 
ATOM   9111  C C   . PRO C 1 217 ? 115.399 144.958 94.127  1.00 14.21 ? 196  PRO C C   1 
ATOM   9112  O O   . PRO C 1 217 ? 116.421 144.802 93.458  1.00 14.21 ? 196  PRO C O   1 
ATOM   9113  C CB  . PRO C 1 217 ? 114.774 146.755 95.766  1.00 14.21 ? 196  PRO C CB  1 
ATOM   9114  C CG  . PRO C 1 217 ? 115.763 147.625 96.482  1.00 14.21 ? 196  PRO C CG  1 
ATOM   9115  C CD  . PRO C 1 217 ? 117.100 147.116 96.065  1.00 14.21 ? 196  PRO C CD  1 
ATOM   9116  N N   . ALA C 1 218 ? 114.185 144.718 93.650  1.00 12.92 ? 197  ALA C N   1 
ATOM   9117  C CA  . ALA C 1 218 ? 113.884 144.802 92.229  1.00 12.92 ? 197  ALA C CA  1 
ATOM   9118  C C   . ALA C 1 218 ? 114.532 143.729 91.359  1.00 12.92 ? 197  ALA C C   1 
ATOM   9119  O O   . ALA C 1 218 ? 114.278 143.685 90.152  1.00 12.92 ? 197  ALA C O   1 
ATOM   9120  C CB  . ALA C 1 218 ? 114.264 146.188 91.718  1.00 12.92 ? 197  ALA C CB  1 
ATOM   9121  N N   . GLY C 1 219 ? 115.369 142.864 91.932  1.00 10.21 ? 198  GLY C N   1 
ATOM   9122  C CA  . GLY C 1 219 ? 115.607 141.582 91.292  1.00 10.21 ? 198  GLY C CA  1 
ATOM   9123  C C   . GLY C 1 219 ? 114.415 140.676 91.488  1.00 10.21 ? 198  GLY C C   1 
ATOM   9124  O O   . GLY C 1 219 ? 114.062 139.890 90.600  1.00 10.21 ? 198  GLY C O   1 
ATOM   9125  N N   . ILE C 1 220 ? 113.758 140.809 92.639  1.00 8.83  ? 199  ILE C N   1 
ATOM   9126  C CA  . ILE C 1 220 ? 112.465 140.187 92.868  1.00 8.83  ? 199  ILE C CA  1 
ATOM   9127  C C   . ILE C 1 220 ? 111.407 140.817 91.972  1.00 8.83  ? 199  ILE C C   1 
ATOM   9128  O O   . ILE C 1 220 ? 110.462 140.147 91.550  1.00 8.83  ? 199  ILE C O   1 
ATOM   9129  C CB  . ILE C 1 220 ? 112.099 140.286 94.358  1.00 8.83  ? 199  ILE C CB  1 
ATOM   9130  C CG1 . ILE C 1 220 ? 113.241 139.733 95.206  1.00 8.83  ? 199  ILE C CG1 1 
ATOM   9131  C CG2 . ILE C 1 220 ? 110.839 139.515 94.655  1.00 8.83  ? 199  ILE C CG2 1 
ATOM   9132  C CD1 . ILE C 1 220 ? 114.184 140.782 95.754  1.00 8.83  ? 199  ILE C CD1 1 
ATOM   9133  N N   . MET C 1 221 ? 111.544 142.108 91.663  1.00 10.56 ? 200  MET C N   1 
ATOM   9134  C CA  . MET C 1 221 ? 110.646 142.721 90.688  1.00 10.56 ? 200  MET C CA  1 
ATOM   9135  C C   . MET C 1 221 ? 110.811 142.089 89.315  1.00 10.56 ? 200  MET C C   1 
ATOM   9136  O O   . MET C 1 221 ? 109.824 141.837 88.619  1.00 10.56 ? 200  MET C O   1 
ATOM   9137  C CB  . MET C 1 221 ? 110.890 144.223 90.602  1.00 10.56 ? 200  MET C CB  1 
ATOM   9138  C CG  . MET C 1 221 ? 110.264 145.046 91.711  1.00 10.56 ? 200  MET C CG  1 
ATOM   9139  S SD  . MET C 1 221 ? 108.564 144.600 92.083  1.00 10.56 ? 200  MET C SD  1 
ATOM   9140  C CE  . MET C 1 221 ? 108.597 144.684 93.863  1.00 10.56 ? 200  MET C CE  1 
ATOM   9141  N N   . VAL C 1 222 ? 112.054 141.838 88.902  1.00 7.46  ? 201  VAL C N   1 
ATOM   9142  C CA  . VAL C 1 222 ? 112.295 141.170 87.627  1.00 7.46  ? 201  VAL C CA  1 
ATOM   9143  C C   . VAL C 1 222 ? 111.691 139.776 87.641  1.00 7.46  ? 201  VAL C C   1 
ATOM   9144  O O   . VAL C 1 222 ? 111.030 139.350 86.684  1.00 7.46  ? 201  VAL C O   1 
ATOM   9145  C CB  . VAL C 1 222 ? 113.803 141.122 87.329  1.00 7.46  ? 201  VAL C CB  1 
ATOM   9146  C CG1 . VAL C 1 222 ? 114.084 140.231 86.131  1.00 7.46  ? 201  VAL C CG1 1 
ATOM   9147  C CG2 . VAL C 1 222 ? 114.341 142.518 87.102  1.00 7.46  ? 201  VAL C CG2 1 
ATOM   9148  N N   . TRP C 1 223 ? 111.898 139.048 88.735  1.00 5.38  ? 202  TRP C N   1 
ATOM   9149  C CA  . TRP C 1 223 ? 111.379 137.691 88.828  1.00 5.38  ? 202  TRP C CA  1 
ATOM   9150  C C   . TRP C 1 223 ? 109.852 137.676 88.793  1.00 5.38  ? 202  TRP C C   1 
ATOM   9151  O O   . TRP C 1 223 ? 109.242 136.812 88.147  1.00 5.38  ? 202  TRP C O   1 
ATOM   9152  C CB  . TRP C 1 223 ? 111.930 137.051 90.098  1.00 5.38  ? 202  TRP C CB  1 
ATOM   9153  C CG  . TRP C 1 223 ? 111.544 135.654 90.324  1.00 5.38  ? 202  TRP C CG  1 
ATOM   9154  C CD1 . TRP C 1 223 ? 112.036 134.557 89.693  1.00 5.38  ? 202  TRP C CD1 1 
ATOM   9155  C CD2 . TRP C 1 223 ? 110.619 135.181 91.296  1.00 5.38  ? 202  TRP C CD2 1 
ATOM   9156  N NE1 . TRP C 1 223 ? 111.452 133.424 90.195  1.00 5.38  ? 202  TRP C NE1 1 
ATOM   9157  C CE2 . TRP C 1 223 ? 110.575 133.783 91.183  1.00 5.38  ? 202  TRP C CE2 1 
ATOM   9158  C CE3 . TRP C 1 223 ? 109.811 135.807 92.245  1.00 5.38  ? 202  TRP C CE3 1 
ATOM   9159  C CZ2 . TRP C 1 223 ? 109.762 133.001 91.984  1.00 5.38  ? 202  TRP C CZ2 1 
ATOM   9160  C CZ3 . TRP C 1 223 ? 109.001 135.034 93.031  1.00 5.38  ? 202  TRP C CZ3 1 
ATOM   9161  C CH2 . TRP C 1 223 ? 108.981 133.643 92.900  1.00 5.38  ? 202  TRP C CH2 1 
ATOM   9162  N N   . ALA C 1 224 ? 109.217 138.632 89.473  1.00 6.29  ? 203  ALA C N   1 
ATOM   9163  C CA  . ALA C 1 224 ? 107.764 138.740 89.423  1.00 6.29  ? 203  ALA C CA  1 
ATOM   9164  C C   . ALA C 1 224 ? 107.283 139.084 88.024  1.00 6.29  ? 203  ALA C C   1 
ATOM   9165  O O   . ALA C 1 224 ? 106.340 138.470 87.524  1.00 6.29  ? 203  ALA C O   1 
ATOM   9166  C CB  . ALA C 1 224 ? 107.276 139.784 90.422  1.00 6.29  ? 203  ALA C CB  1 
ATOM   9167  N N   . ASN C 1 225 ? 107.928 140.043 87.364  1.00 7.26  ? 204  ASN C N   1 
ATOM   9168  C CA  . ASN C 1 225 ? 107.573 140.340 85.985  1.00 7.26  ? 204  ASN C CA  1 
ATOM   9169  C C   . ASN C 1 225 ? 107.759 139.130 85.083  1.00 7.26  ? 204  ASN C C   1 
ATOM   9170  O O   . ASN C 1 225 ? 107.147 139.063 84.012  1.00 7.26  ? 204  ASN C O   1 
ATOM   9171  C CB  . ASN C 1 225 ? 108.405 141.512 85.474  1.00 7.26  ? 204  ASN C CB  1 
ATOM   9172  C CG  . ASN C 1 225 ? 107.997 141.951 84.091  1.00 7.26  ? 204  ASN C CG  1 
ATOM   9173  O OD1 . ASN C 1 225 ? 106.816 141.949 83.752  1.00 7.26  ? 204  ASN C OD1 1 
ATOM   9174  N ND2 . ASN C 1 225 ? 108.974 142.328 83.280  1.00 7.26  ? 204  ASN C ND2 1 
ATOM   9175  N N   . LEU C 1 226 ? 108.595 138.176 85.489  1.00 5.59  ? 205  LEU C N   1 
ATOM   9176  C CA  . LEU C 1 226 ? 108.746 136.959 84.701  1.00 5.59  ? 205  LEU C CA  1 
ATOM   9177  C C   . LEU C 1 226 ? 107.629 135.952 84.962  1.00 5.59  ? 205  LEU C C   1 
ATOM   9178  O O   . LEU C 1 226 ? 107.125 135.335 84.018  1.00 5.59  ? 205  LEU C O   1 
ATOM   9179  C CB  . LEU C 1 226 ? 110.102 136.316 84.978  1.00 5.59  ? 205  LEU C CB  1 
ATOM   9180  C CG  . LEU C 1 226 ? 110.324 134.976 84.283  1.00 5.59  ? 205  LEU C CG  1 
ATOM   9181  C CD1 . LEU C 1 226 ? 110.365 135.165 82.786  1.00 5.59  ? 205  LEU C CD1 1 
ATOM   9182  C CD2 . LEU C 1 226 ? 111.595 134.316 84.772  1.00 5.59  ? 205  LEU C CD2 1 
ATOM   9183  N N   . ILE C 1 227 ? 107.228 135.754 86.221  1.00 3.86  ? 206  ILE C N   1 
ATOM   9184  C CA  . ILE C 1 227 ? 106.379 134.616 86.555  1.00 3.86  ? 206  ILE C CA  1 
ATOM   9185  C C   . ILE C 1 227 ? 104.960 134.999 86.976  1.00 3.86  ? 206  ILE C C   1 
ATOM   9186  O O   . ILE C 1 227 ? 104.025 134.246 86.684  1.00 3.86  ? 206  ILE C O   1 
ATOM   9187  C CB  . ILE C 1 227 ? 107.024 133.720 87.631  1.00 3.86  ? 206  ILE C CB  1 
ATOM   9188  C CG1 . ILE C 1 227 ? 107.000 134.421 88.983  1.00 3.86  ? 206  ILE C CG1 1 
ATOM   9189  C CG2 . ILE C 1 227 ? 108.437 133.315 87.225  1.00 3.86  ? 206  ILE C CG2 1 
ATOM   9190  C CD1 . ILE C 1 227 ? 107.033 133.482 90.121  1.00 3.86  ? 206  ILE C CD1 1 
ATOM   9191  N N   . GLY C 1 228 ? 104.764 136.132 87.645  1.00 4.35  ? 207  GLY C N   1 
ATOM   9192  C CA  . GLY C 1 228 ? 103.604 136.388 88.482  1.00 4.35  ? 207  GLY C CA  1 
ATOM   9193  C C   . GLY C 1 228 ? 102.224 136.006 87.991  1.00 4.35  ? 207  GLY C C   1 
ATOM   9194  O O   . GLY C 1 228 ? 101.329 135.769 88.807  1.00 4.35  ? 207  GLY C O   1 
ATOM   9195  N N   . ASP C 1 229 ? 102.023 135.943 86.674  1.00 4.25  ? 208  ASP C N   1 
ATOM   9196  C CA  . ASP C 1 229 ? 100.698 135.604 86.166  1.00 4.25  ? 208  ASP C CA  1 
ATOM   9197  C C   . ASP C 1 229 ? 100.386 134.122 86.336  1.00 4.25  ? 208  ASP C C   1 
ATOM   9198  O O   . ASP C 1 229 ? 99.213  133.735 86.322  1.00 4.25  ? 208  ASP C O   1 
ATOM   9199  C CB  . ASP C 1 229 ? 100.570 136.012 84.701  1.00 4.25  ? 208  ASP C CB  1 
ATOM   9200  C CG  . ASP C 1 229 ? 101.449 135.195 83.792  1.00 4.25  ? 208  ASP C CG  1 
ATOM   9201  O OD1 . ASP C 1 229 ? 102.405 134.569 84.289  1.00 4.25  ? 208  ASP C OD1 1 
ATOM   9202  O OD2 . ASP C 1 229 ? 101.177 135.173 82.575  1.00 4.25  ? 208  ASP C OD2 1 
ATOM   9203  N N   . LEU C 1 230 ? 101.414 133.284 86.498  1.00 2.84  ? 209  LEU C N   1 
ATOM   9204  C CA  . LEU C 1 230 ? 101.206 131.860 86.736  1.00 2.84  ? 209  LEU C CA  1 
ATOM   9205  C C   . LEU C 1 230 ? 100.446 131.581 88.022  1.00 2.84  ? 209  LEU C C   1 
ATOM   9206  O O   . LEU C 1 230 ? 99.903  130.484 88.176  1.00 2.84  ? 209  LEU C O   1 
ATOM   9207  C CB  . LEU C 1 230 ? 102.546 131.130 86.778  1.00 2.84  ? 209  LEU C CB  1 
ATOM   9208  C CG  . LEU C 1 230 ? 103.144 130.733 85.435  1.00 2.84  ? 209  LEU C CG  1 
ATOM   9209  C CD1 . LEU C 1 230 ? 104.638 130.569 85.565  1.00 2.84  ? 209  LEU C CD1 1 
ATOM   9210  C CD2 . LEU C 1 230 ? 102.514 129.459 84.945  1.00 2.84  ? 209  LEU C CD2 1 
ATOM   9211  N N   . LEU C 1 231 ? 100.400 132.517 88.931  1.00 3.81  ? 210  LEU C N   1 
ATOM   9212  C CA  . LEU C 1 231 ? 99.687  132.337 90.176  1.00 3.81  ? 210  LEU C CA  1 
ATOM   9213  C C   . LEU C 1 231 ? 98.372  133.103 90.141  1.00 3.81  ? 210  LEU C C   1 
ATOM   9214  O O   . LEU C 1 231 ? 98.259  134.101 89.423  1.00 3.81  ? 210  LEU C O   1 
ATOM   9215  C CB  . LEU C 1 231 ? 100.524 132.830 91.361  1.00 3.81  ? 210  LEU C CB  1 
ATOM   9216  C CG  . LEU C 1 231 ? 101.717 131.975 91.771  1.00 3.81  ? 210  LEU C CG  1 
ATOM   9217  C CD1 . LEU C 1 231 ? 102.638 132.772 92.661  1.00 3.81  ? 210  LEU C CD1 1 
ATOM   9218  C CD2 . LEU C 1 231 ? 101.245 130.725 92.474  1.00 3.81  ? 210  LEU C CD2 1 
ATOM   9219  N N   . PRO C 1 232 ? 97.363  132.660 90.881  1.00 4.01  ? 211  PRO C N   1 
ATOM   9220  C CA  . PRO C 1 232 ? 96.123  133.422 90.968  1.00 4.01  ? 211  PRO C CA  1 
ATOM   9221  C C   . PRO C 1 232 ? 96.391  134.824 91.479  1.00 4.01  ? 211  PRO C C   1 
ATOM   9222  O O   . PRO C 1 232 ? 97.203  135.014 92.396  1.00 4.01  ? 211  PRO C O   1 
ATOM   9223  C CB  . PRO C 1 232 ? 95.283  132.614 91.966  1.00 4.01  ? 211  PRO C CB  1 
ATOM   9224  C CG  . PRO C 1 232 ? 95.797  131.241 91.848  1.00 4.01  ? 211  PRO C CG  1 
ATOM   9225  C CD  . PRO C 1 232 ? 97.263  131.367 91.575  1.00 4.01  ? 211  PRO C CD  1 
ATOM   9226  N N   . PRO C 1 233 ? 95.753  135.830 90.892  1.00 4.94  ? 212  PRO C N   1 
ATOM   9227  C CA  . PRO C 1 233 ? 95.956  137.207 91.349  1.00 4.94  ? 212  PRO C CA  1 
ATOM   9228  C C   . PRO C 1 233 ? 95.768  137.375 92.847  1.00 4.94  ? 212  PRO C C   1 
ATOM   9229  O O   . PRO C 1 233 ? 94.693  137.102 93.389  1.00 4.94  ? 212  PRO C O   1 
ATOM   9230  C CB  . PRO C 1 233 ? 94.898  137.977 90.558  1.00 4.94  ? 212  PRO C CB  1 
ATOM   9231  C CG  . PRO C 1 233 ? 94.834  137.239 89.279  1.00 4.94  ? 212  PRO C CG  1 
ATOM   9232  C CD  . PRO C 1 233 ? 94.980  135.784 89.642  1.00 4.94  ? 212  PRO C CD  1 
ATOM   9233  N N   . GLY C 1 234 ? 96.813  137.838 93.520  1.00 6.58  ? 213  GLY C N   1 
ATOM   9234  C CA  . GLY C 1 234 ? 96.806  137.952 94.957  1.00 6.58  ? 213  GLY C CA  1 
ATOM   9235  C C   . GLY C 1 234 ? 97.513  136.839 95.689  1.00 6.58  ? 213  GLY C C   1 
ATOM   9236  O O   . GLY C 1 234 ? 97.405  136.766 96.918  1.00 6.58  ? 213  GLY C O   1 
ATOM   9237  N N   . VAL C 1 235 ? 98.214  135.961 94.980  1.00 4.36  ? 214  VAL C N   1 
ATOM   9238  C CA  . VAL C 1 235 ? 99.003  134.929 95.639  1.00 4.36  ? 214  VAL C CA  1 
ATOM   9239  C C   . VAL C 1 235 ? 100.415 135.418 95.918  1.00 4.36  ? 214  VAL C C   1 
ATOM   9240  O O   . VAL C 1 235 ? 100.961 135.174 96.994  1.00 4.36  ? 214  VAL C O   1 
ATOM   9241  C CB  . VAL C 1 235 ? 98.998  133.640 94.794  1.00 4.36  ? 214  VAL C CB  1 
ATOM   9242  C CG1 . VAL C 1 235 ? 100.052 132.673 95.286  1.00 4.36  ? 214  VAL C CG1 1 
ATOM   9243  C CG2 . VAL C 1 235 ? 97.638  132.985 94.858  1.00 4.36  ? 214  VAL C CG2 1 
ATOM   9244  N N   . LEU C 1 236 ? 101.010 136.142 94.975  1.00 5.31  ? 215  LEU C N   1 
ATOM   9245  C CA  . LEU C 1 236 ? 102.366 136.666 95.115  1.00 5.31  ? 215  LEU C CA  1 
ATOM   9246  C C   . LEU C 1 236 ? 102.292 138.189 95.076  1.00 5.31  ? 215  LEU C C   1 
ATOM   9247  O O   . LEU C 1 236 ? 102.233 138.785 93.998  1.00 5.31  ? 215  LEU C O   1 
ATOM   9248  C CB  . LEU C 1 236 ? 103.276 136.123 94.021  1.00 5.31  ? 215  LEU C CB  1 
ATOM   9249  C CG  . LEU C 1 236 ? 104.694 136.678 93.992  1.00 5.31  ? 215  LEU C CG  1 
ATOM   9250  C CD1 . LEU C 1 236 ? 105.453 136.259 95.230  1.00 5.31  ? 215  LEU C CD1 1 
ATOM   9251  C CD2 . LEU C 1 236 ? 105.407 136.210 92.749  1.00 5.31  ? 215  LEU C CD2 1 
ATOM   9252  N N   . ASN C 1 237 ? 102.290 138.810 96.250  1.00 7.60  ? 216  ASN C N   1 
ATOM   9253  C CA  . ASN C 1 237 ? 102.272 140.259 96.390  1.00 7.60  ? 216  ASN C CA  1 
ATOM   9254  C C   . ASN C 1 237 ? 103.646 140.716 96.851  1.00 7.60  ? 216  ASN C C   1 
ATOM   9255  O O   . ASN C 1 237 ? 104.173 140.194 97.838  1.00 7.60  ? 216  ASN C O   1 
ATOM   9256  C CB  . ASN C 1 237 ? 101.216 140.697 97.402  1.00 7.60  ? 216  ASN C CB  1 
ATOM   9257  C CG  . ASN C 1 237 ? 99.820  140.343 96.971  1.00 7.60  ? 216  ASN C CG  1 
ATOM   9258  O OD1 . ASN C 1 237 ? 99.476  140.451 95.799  1.00 7.60  ? 216  ASN C OD1 1 
ATOM   9259  N ND2 . ASN C 1 237 ? 99.002  139.917 97.920  1.00 7.60  ? 216  ASN C ND2 1 
ATOM   9260  N N   . ILE C 1 238 ? 104.227 141.685 96.152  1.00 7.35  ? 217  ILE C N   1 
ATOM   9261  C CA  . ILE C 1 238 ? 105.576 142.149 96.452  1.00 7.35  ? 217  ILE C CA  1 
ATOM   9262  C C   . ILE C 1 238 ? 105.531 143.663 96.602  1.00 7.35  ? 217  ILE C C   1 
ATOM   9263  O O   . ILE C 1 238 ? 105.673 144.395 95.618  1.00 7.35  ? 217  ILE C O   1 
ATOM   9264  C CB  . ILE C 1 238 ? 106.582 141.732 95.378  1.00 7.35  ? 217  ILE C CB  1 
ATOM   9265  C CG1 . ILE C 1 238 ? 106.401 140.263 95.025  1.00 7.35  ? 217  ILE C CG1 1 
ATOM   9266  C CG2 . ILE C 1 238 ? 107.984 141.930 95.884  1.00 7.35  ? 217  ILE C CG2 1 
ATOM   9267  C CD1 . ILE C 1 238 ? 107.288 139.802 93.920  1.00 7.35  ? 217  ILE C CD1 1 
ATOM   9268  N N   . VAL C 1 239 ? 105.353 144.141 97.833  1.00 10.79 ? 218  VAL C N   1 
ATOM   9269  C CA  . VAL C 1 239 ? 105.494 145.562 98.132  1.00 10.79 ? 218  VAL C CA  1 
ATOM   9270  C C   . VAL C 1 239 ? 106.981 145.860 98.220  1.00 10.79 ? 218  VAL C C   1 
ATOM   9271  O O   . VAL C 1 239 ? 107.802 144.940 98.277  1.00 10.79 ? 218  VAL C O   1 
ATOM   9272  C CB  . VAL C 1 239 ? 104.780 145.960 99.435  1.00 10.79 ? 218  VAL C CB  1 
ATOM   9273  C CG1 . VAL C 1 239 ? 103.361 145.464 99.426  1.00 10.79 ? 218  VAL C CG1 1 
ATOM   9274  C CG2 . VAL C 1 239 ? 105.534 145.441 100.636 1.00 10.79 ? 218  VAL C CG2 1 
ATOM   9275  N N   . ASN C 1 240 ? 107.347 147.136 98.233  1.00 15.83 ? 219  ASN C N   1 
ATOM   9276  C CA  . ASN C 1 240 ? 108.756 147.471 98.329  1.00 15.83 ? 219  ASN C CA  1 
ATOM   9277  C C   . ASN C 1 240 ? 108.898 148.835 98.986  1.00 15.83 ? 219  ASN C C   1 
ATOM   9278  O O   . ASN C 1 240 ? 107.979 149.657 98.960  1.00 15.83 ? 219  ASN C O   1 
ATOM   9279  C CB  . ASN C 1 240 ? 109.412 147.429 96.950  1.00 15.83 ? 219  ASN C CB  1 
ATOM   9280  C CG  . ASN C 1 240 ? 110.877 147.097 97.019  1.00 15.83 ? 219  ASN C CG  1 
ATOM   9281  O OD1 . ASN C 1 240 ? 111.488 147.144 98.085  1.00 15.83 ? 219  ASN C OD1 1 
ATOM   9282  N ND2 . ASN C 1 240 ? 111.439 146.687 95.890  1.00 15.83 ? 219  ASN C ND2 1 
ATOM   9283  N N   . GLY C 1 241 ? 110.060 149.061 99.593  1.00 20.26 ? 220  GLY C N   1 
ATOM   9284  C CA  . GLY C 1 241 ? 110.310 150.301 100.300 1.00 20.26 ? 220  GLY C CA  1 
ATOM   9285  C C   . GLY C 1 241 ? 111.446 150.205 101.297 1.00 20.26 ? 220  GLY C C   1 
ATOM   9286  O O   . GLY C 1 241 ? 112.504 149.659 100.980 1.00 20.26 ? 220  GLY C O   1 
ATOM   9287  N N   . PHE C 1 242 ? 111.243 150.725 102.505 1.00 23.50 ? 221  PHE C N   1 
ATOM   9288  C CA  . PHE C 1 242 ? 112.276 150.730 103.529 1.00 23.50 ? 221  PHE C CA  1 
ATOM   9289  C C   . PHE C 1 242 ? 111.856 149.862 104.707 1.00 23.50 ? 221  PHE C C   1 
ATOM   9290  O O   . PHE C 1 242 ? 110.668 149.636 104.950 1.00 23.50 ? 221  PHE C O   1 
ATOM   9291  C CB  . PHE C 1 242 ? 112.585 152.154 104.007 1.00 23.50 ? 221  PHE C CB  1 
ATOM   9292  C CG  . PHE C 1 242 ? 113.394 152.957 103.030 1.00 23.50 ? 221  PHE C CG  1 
ATOM   9293  C CD1 . PHE C 1 242 ? 114.752 152.736 102.890 1.00 23.50 ? 221  PHE C CD1 1 
ATOM   9294  C CD2 . PHE C 1 242 ? 112.796 153.929 102.250 1.00 23.50 ? 221  PHE C CD2 1 
ATOM   9295  C CE1 . PHE C 1 242 ? 115.496 153.468 101.994 1.00 23.50 ? 221  PHE C CE1 1 
ATOM   9296  C CE2 . PHE C 1 242 ? 113.538 154.664 101.352 1.00 23.50 ? 221  PHE C CE2 1 
ATOM   9297  C CZ  . PHE C 1 242 ? 114.889 154.434 101.225 1.00 23.50 ? 221  PHE C CZ  1 
ATOM   9298  N N   . GLY C 1 243 ? 112.859 149.367 105.434 1.00 22.01 ? 222  GLY C N   1 
ATOM   9299  C CA  . GLY C 1 243 ? 112.586 148.463 106.538 1.00 22.01 ? 222  GLY C CA  1 
ATOM   9300  C C   . GLY C 1 243 ? 111.773 149.110 107.642 1.00 22.01 ? 222  GLY C C   1 
ATOM   9301  O O   . GLY C 1 243 ? 110.844 148.503 108.179 1.00 22.01 ? 222  GLY C O   1 
ATOM   9302  N N   . LEU C 1 244 ? 112.115 150.347 107.999 1.00 25.23 ? 223  LEU C N   1 
ATOM   9303  C CA  . LEU C 1 244 ? 111.335 151.096 108.975 1.00 25.23 ? 223  LEU C CA  1 
ATOM   9304  C C   . LEU C 1 244 ? 110.085 151.717 108.373 1.00 25.23 ? 223  LEU C C   1 
ATOM   9305  O O   . LEU C 1 244 ? 109.216 152.174 109.123 1.00 25.23 ? 223  LEU C O   1 
ATOM   9306  C CB  . LEU C 1 244 ? 112.204 152.181 109.619 1.00 25.23 ? 223  LEU C CB  1 
ATOM   9307  C CG  . LEU C 1 244 ? 112.910 153.190 108.706 1.00 25.23 ? 223  LEU C CG  1 
ATOM   9308  C CD1 . LEU C 1 244 ? 112.036 154.396 108.385 1.00 25.23 ? 223  LEU C CD1 1 
ATOM   9309  C CD2 . LEU C 1 244 ? 114.228 153.630 109.326 1.00 25.23 ? 223  LEU C CD2 1 
ATOM   9310  N N   . GLU C 1 245 ? 109.973 151.739 107.045 1.00 26.05 ? 224  GLU C N   1 
ATOM   9311  C CA  . GLU C 1 245 ? 108.840 152.354 106.365 1.00 26.05 ? 224  GLU C CA  1 
ATOM   9312  C C   . GLU C 1 245 ? 107.807 151.320 105.935 1.00 26.05 ? 224  GLU C C   1 
ATOM   9313  O O   . GLU C 1 245 ? 106.640 151.407 106.321 1.00 26.05 ? 224  GLU C O   1 
ATOM   9314  C CB  . GLU C 1 245 ? 109.335 153.157 105.156 1.00 26.05 ? 224  GLU C CB  1 
ATOM   9315  C CG  . GLU C 1 245 ? 109.808 154.561 105.487 1.00 26.05 ? 224  GLU C CG  1 
ATOM   9316  C CD  . GLU C 1 245 ? 109.849 155.462 104.269 1.00 26.05 ? 224  GLU C CD  1 
ATOM   9317  O OE1 . GLU C 1 245 ? 109.623 154.956 103.150 1.00 26.05 ? 224  GLU C OE1 1 
ATOM   9318  O OE2 . GLU C 1 245 ? 110.106 156.674 104.427 1.00 26.05 ? 224  GLU C OE2 1 
ATOM   9319  N N   . ALA C 1 246 ? 108.222 150.330 105.145 1.00 19.75 ? 225  ALA C N   1 
ATOM   9320  C CA  . ALA C 1 246 ? 107.311 149.323 104.614 1.00 19.75 ? 225  ALA C CA  1 
ATOM   9321  C C   . ALA C 1 246 ? 107.178 148.112 105.532 1.00 19.75 ? 225  ALA C C   1 
ATOM   9322  O O   . ALA C 1 246 ? 106.065 147.650 105.794 1.00 19.75 ? 225  ALA C O   1 
ATOM   9323  C CB  . ALA C 1 246 ? 107.778 148.878 103.226 1.00 19.75 ? 225  ALA C CB  1 
ATOM   9324  N N   . GLY C 1 247 ? 108.303 147.588 106.020 1.00 21.38 ? 226  GLY C N   1 
ATOM   9325  C CA  . GLY C 1 247 ? 108.272 146.330 106.749 1.00 21.38 ? 226  GLY C CA  1 
ATOM   9326  C C   . GLY C 1 247 ? 107.589 146.416 108.100 1.00 21.38 ? 226  GLY C C   1 
ATOM   9327  O O   . GLY C 1 247 ? 106.873 145.494 108.498 1.00 21.38 ? 226  GLY C O   1 
ATOM   9328  N N   . LYS C 1 248 ? 107.819 147.506 108.832 1.00 22.64 ? 227  LYS C N   1 
ATOM   9329  C CA  . LYS C 1 248 ? 107.289 147.604 110.192 1.00 22.64 ? 227  LYS C CA  1 
ATOM   9330  C C   . LYS C 1 248 ? 105.776 147.440 110.253 1.00 22.64 ? 227  LYS C C   1 
ATOM   9331  O O   . LYS C 1 248 ? 105.297 146.690 111.122 1.00 22.64 ? 227  LYS C O   1 
ATOM   9332  C CB  . LYS C 1 248 ? 107.741 148.923 110.830 1.00 22.64 ? 227  LYS C CB  1 
ATOM   9333  C CG  . LYS C 1 248 ? 109.247 149.043 111.032 1.00 22.64 ? 227  LYS C CG  1 
ATOM   9334  C CD  . LYS C 1 248 ? 109.906 147.697 111.322 1.00 22.64 ? 227  LYS C CD  1 
ATOM   9335  C CE  . LYS C 1 248 ? 109.828 147.334 112.797 1.00 22.64 ? 227  LYS C CE  1 
ATOM   9336  N NZ  . LYS C 1 248 ? 110.912 146.398 113.200 1.00 22.64 ? 227  LYS C NZ  1 
ATOM   9337  N N   . PRO C 1 249 ? 104.970 148.089 109.402 1.00 22.21 ? 228  PRO C N   1 
ATOM   9338  C CA  . PRO C 1 249 ? 103.532 147.767 109.403 1.00 22.21 ? 228  PRO C CA  1 
ATOM   9339  C C   . PRO C 1 249 ? 103.245 146.333 108.999 1.00 22.21 ? 228  PRO C C   1 
ATOM   9340  O O   . PRO C 1 249 ? 102.255 145.749 109.458 1.00 22.21 ? 228  PRO C O   1 
ATOM   9341  C CB  . PRO C 1 249 ? 102.945 148.775 108.403 1.00 22.21 ? 228  PRO C CB  1 
ATOM   9342  C CG  . PRO C 1 249 ? 103.965 149.853 108.295 1.00 22.21 ? 228  PRO C CG  1 
ATOM   9343  C CD  . PRO C 1 249 ? 105.275 149.164 108.442 1.00 22.21 ? 228  PRO C CD  1 
ATOM   9344  N N   . LEU C 1 250 ? 104.085 145.750 108.140 1.00 19.43 ? 229  LEU C N   1 
ATOM   9345  C CA  . LEU C 1 250 ? 103.873 144.373 107.705 1.00 19.43 ? 229  LEU C CA  1 
ATOM   9346  C C   . LEU C 1 250 ? 104.247 143.384 108.803 1.00 19.43 ? 229  LEU C C   1 
ATOM   9347  O O   . LEU C 1 250 ? 103.434 142.540 109.194 1.00 19.43 ? 229  LEU C O   1 
ATOM   9348  C CB  . LEU C 1 250 ? 104.679 144.094 106.436 1.00 19.43 ? 229  LEU C CB  1 
ATOM   9349  C CG  . LEU C 1 250 ? 104.781 142.626 106.018 1.00 19.43 ? 229  LEU C CG  1 
ATOM   9350  C CD1 . LEU C 1 250 ? 103.423 142.096 105.603 1.00 19.43 ? 229  LEU C CD1 1 
ATOM   9351  C CD2 . LEU C 1 250 ? 105.791 142.448 104.900 1.00 19.43 ? 229  LEU C CD2 1 
ATOM   9352  N N   . ALA C 1 251 ? 105.480 143.475 109.309 1.00 20.68 ? 230  ALA C N   1 
ATOM   9353  C CA  . ALA C 1 251 ? 105.943 142.519 110.309 1.00 20.68 ? 230  ALA C CA  1 
ATOM   9354  C C   . ALA C 1 251 ? 105.120 142.613 111.585 1.00 20.68 ? 230  ALA C C   1 
ATOM   9355  O O   . ALA C 1 251 ? 104.972 141.624 112.313 1.00 20.68 ? 230  ALA C O   1 
ATOM   9356  C CB  . ALA C 1 251 ? 107.424 142.748 110.604 1.00 20.68 ? 230  ALA C CB  1 
ATOM   9357  N N   . SER C 1 252 ? 104.585 143.794 111.880 1.00 21.69 ? 231  SER C N   1 
ATOM   9358  C CA  . SER C 1 252 ? 103.673 143.991 113.005 1.00 21.69 ? 231  SER C CA  1 
ATOM   9359  C C   . SER C 1 252 ? 102.275 144.164 112.423 1.00 21.69 ? 231  SER C C   1 
ATOM   9360  O O   . SER C 1 252 ? 101.805 145.282 112.209 1.00 21.69 ? 231  SER C O   1 
ATOM   9361  C CB  . SER C 1 252 ? 104.090 145.192 113.846 1.00 21.69 ? 231  SER C CB  1 
ATOM   9362  O OG  . SER C 1 252 ? 104.019 146.391 113.094 1.00 21.69 ? 231  SER C OG  1 
ATOM   9363  N N   . SER C 1 253 ? 101.608 143.044 112.162 1.00 21.18 ? 232  SER C N   1 
ATOM   9364  C CA  . SER C 1 253 ? 100.270 143.062 111.583 1.00 21.18 ? 232  SER C CA  1 
ATOM   9365  C C   . SER C 1 253 ? 99.449  141.951 112.215 1.00 21.18 ? 232  SER C C   1 
ATOM   9366  O O   . SER C 1 253 ? 99.883  140.796 112.236 1.00 21.18 ? 232  SER C O   1 
ATOM   9367  C CB  . SER C 1 253 ? 100.322 142.893 110.065 1.00 21.18 ? 232  SER C CB  1 
ATOM   9368  O OG  . SER C 1 253 ? 99.026  142.954 109.507 1.00 21.18 ? 232  SER C OG  1 
ATOM   9369  N N   . ASN C 1 254 ? 98.271  142.298 112.727 1.00 25.31 ? 233  ASN C N   1 
ATOM   9370  C CA  . ASN C 1 254 ? 97.370  141.314 113.313 1.00 25.31 ? 233  ASN C CA  1 
ATOM   9371  C C   . ASN C 1 254 ? 96.604  140.516 112.265 1.00 25.31 ? 233  ASN C C   1 
ATOM   9372  O O   . ASN C 1 254 ? 95.701  139.754 112.627 1.00 25.31 ? 233  ASN C O   1 
ATOM   9373  C CB  . ASN C 1 254 ? 96.392  141.998 114.275 1.00 25.31 ? 233  ASN C CB  1 
ATOM   9374  C CG  . ASN C 1 254 ? 95.317  142.793 113.556 1.00 25.31 ? 233  ASN C CG  1 
ATOM   9375  O OD1 . ASN C 1 254 ? 95.496  143.218 112.415 1.00 25.31 ? 233  ASN C OD1 1 
ATOM   9376  N ND2 . ASN C 1 254 ? 94.188  142.994 114.225 1.00 25.31 ? 233  ASN C ND2 1 
ATOM   9377  N N   . ARG C 1 255 ? 96.939  140.680 110.984 1.00 22.21 ? 234  ARG C N   1 
ATOM   9378  C CA  . ARG C 1 255 ? 96.305  139.933 109.902 1.00 22.21 ? 234  ARG C CA  1 
ATOM   9379  C C   . ARG C 1 255 ? 97.093  138.680 109.540 1.00 22.21 ? 234  ARG C C   1 
ATOM   9380  O O   . ARG C 1 255 ? 96.560  137.568 109.605 1.00 22.21 ? 234  ARG C O   1 
ATOM   9381  C CB  . ARG C 1 255 ? 96.141  140.831 108.669 1.00 22.21 ? 234  ARG C CB  1 
ATOM   9382  C CG  . ARG C 1 255 ? 95.062  141.879 108.817 1.00 22.21 ? 234  ARG C CG  1 
ATOM   9383  C CD  . ARG C 1 255 ? 95.299  143.062 107.895 1.00 22.21 ? 234  ARG C CD  1 
ATOM   9384  N NE  . ARG C 1 255 ? 95.065  142.739 106.491 1.00 22.21 ? 234  ARG C NE  1 
ATOM   9385  C CZ  . ARG C 1 255 ? 93.883  142.421 105.973 1.00 22.21 ? 234  ARG C CZ  1 
ATOM   9386  N NH1 . ARG C 1 255 ? 92.797  142.384 106.737 1.00 22.21 ? 234  ARG C NH1 1 
ATOM   9387  N NH2 . ARG C 1 255 ? 93.783  142.144 104.681 1.00 22.21 ? 234  ARG C NH2 1 
ATOM   9388  N N   . ILE C 1 256 ? 98.360  138.841 109.159 1.00 18.17 ? 235  ILE C N   1 
ATOM   9389  C CA  . ILE C 1 256 ? 99.172  137.703 108.746 1.00 18.17 ? 235  ILE C CA  1 
ATOM   9390  C C   . ILE C 1 256 ? 99.483  136.835 109.956 1.00 18.17 ? 235  ILE C C   1 
ATOM   9391  O O   . ILE C 1 256 ? 99.926  137.330 111.000 1.00 18.17 ? 235  ILE C O   1 
ATOM   9392  C CB  . ILE C 1 256 ? 100.452 138.178 108.045 1.00 18.17 ? 235  ILE C CB  1 
ATOM   9393  C CG1 . ILE C 1 256 ? 101.182 139.216 108.890 1.00 18.17 ? 235  ILE C CG1 1 
ATOM   9394  C CG2 . ILE C 1 256 ? 100.125 138.758 106.694 1.00 18.17 ? 235  ILE C CG2 1 
ATOM   9395  C CD1 . ILE C 1 256 ? 102.585 139.476 108.429 1.00 18.17 ? 235  ILE C CD1 1 
ATOM   9396  N N   . ALA C 1 257 ? 99.239  135.530 109.822 1.00 19.63 ? 236  ALA C N   1 
ATOM   9397  C CA  . ALA C 1 257 ? 99.389  134.629 110.958 1.00 19.63 ? 236  ALA C CA  1 
ATOM   9398  C C   . ALA C 1 257 ? 100.846 134.451 111.358 1.00 19.63 ? 236  ALA C C   1 
ATOM   9399  O O   . ALA C 1 257 ? 101.140 134.265 112.544 1.00 19.63 ? 236  ALA C O   1 
ATOM   9400  C CB  . ALA C 1 257 ? 98.760  133.274 110.641 1.00 19.63 ? 236  ALA C CB  1 
ATOM   9401  N N   . LYS C 1 258 ? 101.767 134.502 110.398 1.00 17.90 ? 237  LYS C N   1 
ATOM   9402  C CA  . LYS C 1 258 ? 103.172 134.255 110.680 1.00 17.90 ? 237  LYS C CA  1 
ATOM   9403  C C   . LYS C 1 258 ? 104.040 135.218 109.885 1.00 17.90 ? 237  LYS C C   1 
ATOM   9404  O O   . LYS C 1 258 ? 103.625 135.743 108.849 1.00 17.90 ? 237  LYS C O   1 
ATOM   9405  C CB  . LYS C 1 258 ? 103.561 132.807 110.354 1.00 17.90 ? 237  LYS C CB  1 
ATOM   9406  C CG  . LYS C 1 258 ? 103.081 131.794 111.379 1.00 17.90 ? 237  LYS C CG  1 
ATOM   9407  C CD  . LYS C 1 258 ? 104.241 131.035 111.998 1.00 17.90 ? 237  LYS C CD  1 
ATOM   9408  C CE  . LYS C 1 258 ? 103.744 129.850 112.806 1.00 17.90 ? 237  LYS C CE  1 
ATOM   9409  N NZ  . LYS C 1 258 ? 104.855 128.972 113.255 1.00 17.90 ? 237  LYS C NZ  1 
ATOM   9410  N N   . ILE C 1 259 ? 105.251 135.443 110.386 1.00 19.18 ? 238  ILE C N   1 
ATOM   9411  C CA  . ILE C 1 259 ? 106.224 136.289 109.706 1.00 19.18 ? 238  ILE C CA  1 
ATOM   9412  C C   . ILE C 1 259 ? 107.514 135.510 109.503 1.00 19.18 ? 238  ILE C C   1 
ATOM   9413  O O   . ILE C 1 259 ? 108.243 135.240 110.456 1.00 19.18 ? 238  ILE C O   1 
ATOM   9414  C CB  . ILE C 1 259 ? 106.499 137.595 110.480 1.00 19.18 ? 238  ILE C CB  1 
ATOM   9415  C CG1 . ILE C 1 259 ? 105.238 138.458 110.574 1.00 19.18 ? 238  ILE C CG1 1 
ATOM   9416  C CG2 . ILE C 1 259 ? 107.619 138.377 109.818 1.00 19.18 ? 238  ILE C CG2 1 
ATOM   9417  C CD1 . ILE C 1 259 ? 104.391 138.196 111.810 1.00 19.18 ? 238  ILE C CD1 1 
ATOM   9418  N N   . GLY C 1 287 ? 123.126 134.236 111.865 1.00 29.04 ? 266  GLY C N   1 
ATOM   9419  C CA  . GLY C 1 287 ? 124.415 134.713 111.403 1.00 29.04 ? 266  GLY C CA  1 
ATOM   9420  C C   . GLY C 1 287 ? 125.442 134.895 112.503 1.00 29.04 ? 266  GLY C C   1 
ATOM   9421  O O   . GLY C 1 287 ? 125.318 135.792 113.336 1.00 29.04 ? 266  GLY C O   1 
ATOM   9422  N N   . GLY C 1 288 ? 126.465 134.047 112.500 1.00 24.87 ? 267  GLY C N   1 
ATOM   9423  C CA  . GLY C 1 288 ? 127.519 134.101 113.506 1.00 24.87 ? 267  GLY C CA  1 
ATOM   9424  C C   . GLY C 1 288 ? 128.860 133.764 112.923 1.00 24.87 ? 267  GLY C C   1 
ATOM   9425  O O   . GLY C 1 288 ? 129.154 134.119 111.774 1.00 24.87 ? 267  GLY C O   1 
ATOM   9426  N N   . LYS C 1 289 ? 129.690 133.084 113.708 1.00 19.38 ? 268  LYS C N   1 
ATOM   9427  C CA  . LYS C 1 289 ? 131.026 132.683 113.291 1.00 19.38 ? 268  LYS C CA  1 
ATOM   9428  C C   . LYS C 1 289 ? 131.067 131.169 113.156 1.00 19.38 ? 268  LYS C C   1 
ATOM   9429  O O   . LYS C 1 289 ? 130.764 130.450 114.113 1.00 19.38 ? 268  LYS C O   1 
ATOM   9430  C CB  . LYS C 1 289 ? 132.076 133.160 114.294 1.00 19.38 ? 268  LYS C CB  1 
ATOM   9431  C CG  . LYS C 1 289 ? 132.541 134.586 114.061 1.00 19.38 ? 268  LYS C CG  1 
ATOM   9432  C CD  . LYS C 1 289 ? 133.747 134.624 113.142 1.00 19.38 ? 268  LYS C CD  1 
ATOM   9433  C CE  . LYS C 1 289 ? 134.254 136.038 112.964 1.00 19.38 ? 268  LYS C CE  1 
ATOM   9434  N NZ  . LYS C 1 289 ? 135.399 136.115 112.022 1.00 19.38 ? 268  LYS C NZ  1 
ATOM   9435  N N   . SER C 1 290 ? 131.435 130.691 111.974 1.00 10.89 ? 269  SER C N   1 
ATOM   9436  C CA  . SER C 1 290 ? 131.376 129.264 111.662 1.00 10.89 ? 269  SER C CA  1 
ATOM   9437  C C   . SER C 1 290 ? 132.775 128.689 111.553 1.00 10.89 ? 269  SER C C   1 
ATOM   9438  O O   . SER C 1 290 ? 133.505 129.021 110.600 1.00 10.89 ? 269  SER C O   1 
ATOM   9439  C CB  . SER C 1 290 ? 130.604 129.022 110.368 1.00 10.89 ? 269  SER C CB  1 
ATOM   9440  O OG  . SER C 1 290 ? 129.305 129.580 110.447 1.00 10.89 ? 269  SER C OG  1 
ATOM   9441  N N   . PRO C 1 291 ? 133.188 127.829 112.477 1.00 6.53  ? 270  PRO C N   1 
ATOM   9442  C CA  . PRO C 1 291 ? 134.530 127.250 112.404 1.00 6.53  ? 270  PRO C CA  1 
ATOM   9443  C C   . PRO C 1 291 ? 134.706 126.366 111.179 1.00 6.53  ? 270  PRO C C   1 
ATOM   9444  O O   . PRO C 1 291 ? 133.752 125.853 110.595 1.00 6.53  ? 270  PRO C O   1 
ATOM   9445  C CB  . PRO C 1 291 ? 134.643 126.439 113.698 1.00 6.53  ? 270  PRO C CB  1 
ATOM   9446  C CG  . PRO C 1 291 ? 133.258 126.314 114.217 1.00 6.53  ? 270  PRO C CG  1 
ATOM   9447  C CD  . PRO C 1 291 ? 132.494 127.479 113.726 1.00 6.53  ? 270  PRO C CD  1 
ATOM   9448  N N   . ASN C 1 292 ? 135.962 126.218 110.781 1.00 5.56  ? 271  ASN C N   1 
ATOM   9449  C CA  . ASN C 1 292 ? 136.355 125.427 109.620 1.00 5.56  ? 271  ASN C CA  1 
ATOM   9450  C C   . ASN C 1 292 ? 137.543 124.547 109.992 1.00 5.56  ? 271  ASN C C   1 
ATOM   9451  O O   . ASN C 1 292 ? 138.583 124.565 109.338 1.00 5.56  ? 271  ASN C O   1 
ATOM   9452  C CB  . ASN C 1 292 ? 136.670 126.322 108.424 1.00 5.56  ? 271  ASN C CB  1 
ATOM   9453  C CG  . ASN C 1 292 ? 136.357 125.658 107.093 1.00 5.56  ? 271  ASN C CG  1 
ATOM   9454  O OD1 . ASN C 1 292 ? 136.277 124.438 106.999 1.00 5.56  ? 271  ASN C OD1 1 
ATOM   9455  N ND2 . ASN C 1 292 ? 136.182 126.465 106.056 1.00 5.56  ? 271  ASN C ND2 1 
ATOM   9456  N N   . ILE C 1 293 ? 137.399 123.799 111.091 1.00 4.47  ? 272  ILE C N   1 
ATOM   9457  C CA  . ILE C 1 293 ? 138.502 123.047 111.681 1.00 4.47  ? 272  ILE C CA  1 
ATOM   9458  C C   . ILE C 1 293 ? 139.220 122.196 110.641 1.00 4.47  ? 272  ILE C C   1 
ATOM   9459  O O   . ILE C 1 293 ? 138.594 121.517 109.822 1.00 4.47  ? 272  ILE C O   1 
ATOM   9460  C CB  . ILE C 1 293 ? 137.982 122.167 112.832 1.00 4.47  ? 272  ILE C CB  1 
ATOM   9461  C CG1 . ILE C 1 293 ? 137.176 122.996 113.824 1.00 4.47  ? 272  ILE C CG1 1 
ATOM   9462  C CG2 . ILE C 1 293 ? 139.135 121.536 113.561 1.00 4.47  ? 272  ILE C CG2 1 
ATOM   9463  C CD1 . ILE C 1 293 ? 135.692 122.838 113.702 1.00 4.47  ? 272  ILE C CD1 1 
ATOM   9464  N N   . PHE C 1 294 ? 140.551 122.237 110.673 1.00 5.47  ? 273  PHE C N   1 
ATOM   9465  C CA  . PHE C 1 294 ? 141.399 121.379 109.853 1.00 5.47  ? 273  PHE C CA  1 
ATOM   9466  C C   . PHE C 1 294 ? 142.271 120.555 110.788 1.00 5.47  ? 273  PHE C C   1 
ATOM   9467  O O   . PHE C 1 294 ? 143.100 121.110 111.514 1.00 5.47  ? 273  PHE C O   1 
ATOM   9468  C CB  . PHE C 1 294 ? 142.269 122.192 108.896 1.00 5.47  ? 273  PHE C CB  1 
ATOM   9469  C CG  . PHE C 1 294 ? 141.534 122.727 107.710 1.00 5.47  ? 273  PHE C CG  1 
ATOM   9470  C CD1 . PHE C 1 294 ? 141.445 121.996 106.547 1.00 5.47  ? 273  PHE C CD1 1 
ATOM   9471  C CD2 . PHE C 1 294 ? 140.951 123.972 107.751 1.00 5.47  ? 273  PHE C CD2 1 
ATOM   9472  C CE1 . PHE C 1 294 ? 140.767 122.491 105.460 1.00 5.47  ? 273  PHE C CE1 1 
ATOM   9473  C CE2 . PHE C 1 294 ? 140.274 124.467 106.670 1.00 5.47  ? 273  PHE C CE2 1 
ATOM   9474  C CZ  . PHE C 1 294 ? 140.185 123.728 105.523 1.00 5.47  ? 273  PHE C CZ  1 
ATOM   9475  N N   . PHE C 1 295 ? 142.090 119.241 110.773 1.00 6.78  ? 274  PHE C N   1 
ATOM   9476  C CA  . PHE C 1 295 ? 142.907 118.346 111.575 1.00 6.78  ? 274  PHE C CA  1 
ATOM   9477  C C   . PHE C 1 295 ? 144.160 117.947 110.806 1.00 6.78  ? 274  PHE C C   1 
ATOM   9478  O O   . PHE C 1 295 ? 144.252 118.125 109.592 1.00 6.78  ? 274  PHE C O   1 
ATOM   9479  C CB  . PHE C 1 295 ? 142.114 117.104 111.976 1.00 6.78  ? 274  PHE C CB  1 
ATOM   9480  C CG  . PHE C 1 295 ? 141.084 117.366 113.029 1.00 6.78  ? 274  PHE C CG  1 
ATOM   9481  C CD1 . PHE C 1 295 ? 139.813 117.775 112.684 1.00 6.78  ? 274  PHE C CD1 1 
ATOM   9482  C CD2 . PHE C 1 295 ? 141.389 117.213 114.363 1.00 6.78  ? 274  PHE C CD2 1 
ATOM   9483  C CE1 . PHE C 1 295 ? 138.870 118.017 113.647 1.00 6.78  ? 274  PHE C CE1 1 
ATOM   9484  C CE2 . PHE C 1 295 ? 140.444 117.458 115.329 1.00 6.78  ? 274  PHE C CE2 1 
ATOM   9485  C CZ  . PHE C 1 295 ? 139.186 117.862 114.970 1.00 6.78  ? 274  PHE C CZ  1 
ATOM   9486  N N   . ALA C 1 296 ? 145.133 117.398 111.535 1.00 12.01 ? 275  ALA C N   1 
ATOM   9487  C CA  . ALA C 1 296 ? 146.374 116.965 110.903 1.00 12.01 ? 275  ALA C CA  1 
ATOM   9488  C C   . ALA C 1 296 ? 146.143 115.849 109.903 1.00 12.01 ? 275  ALA C C   1 
ATOM   9489  O O   . ALA C 1 296 ? 147.033 115.558 109.098 1.00 12.01 ? 275  ALA C O   1 
ATOM   9490  C CB  . ALA C 1 296 ? 147.379 116.503 111.953 1.00 12.01 ? 275  ALA C CB  1 
ATOM   9491  N N   . ASP C 1 297 ? 144.972 115.213 109.946 1.00 12.11 ? 276  ASP C N   1 
ATOM   9492  C CA  . ASP C 1 297 ? 144.666 114.135 109.018 1.00 12.11 ? 276  ASP C CA  1 
ATOM   9493  C C   . ASP C 1 297 ? 144.718 114.617 107.574 1.00 12.11 ? 276  ASP C C   1 
ATOM   9494  O O   . ASP C 1 297 ? 145.244 113.920 106.699 1.00 12.11 ? 276  ASP C O   1 
ATOM   9495  C CB  . ASP C 1 297 ? 143.286 113.564 109.334 1.00 12.11 ? 276  ASP C CB  1 
ATOM   9496  C CG  . ASP C 1 297 ? 143.163 113.092 110.766 1.00 12.11 ? 276  ASP C CG  1 
ATOM   9497  O OD1 . ASP C 1 297 ? 144.186 112.695 111.357 1.00 12.11 ? 276  ASP C OD1 1 
ATOM   9498  O OD2 . ASP C 1 297 ? 142.038 113.123 111.305 1.00 12.11 ? 276  ASP C OD2 1 
ATOM   9499  N N   . VAL C 1 298 ? 144.189 115.816 107.311 1.00 11.77 ? 277  VAL C N   1 
ATOM   9500  C CA  . VAL C 1 298 ? 144.003 116.289 105.944 1.00 11.77 ? 277  VAL C CA  1 
ATOM   9501  C C   . VAL C 1 298 ? 145.317 116.418 105.194 1.00 11.77 ? 277  VAL C C   1 
ATOM   9502  O O   . VAL C 1 298 ? 145.319 116.471 103.962 1.00 11.77 ? 277  VAL C O   1 
ATOM   9503  C CB  . VAL C 1 298 ? 143.264 117.643 105.937 1.00 11.77 ? 277  VAL C CB  1 
ATOM   9504  C CG1 . VAL C 1 298 ? 141.946 117.536 106.668 1.00 11.77 ? 277  VAL C CG1 1 
ATOM   9505  C CG2 . VAL C 1 298 ? 144.126 118.731 106.524 1.00 11.77 ? 277  VAL C CG2 1 
ATOM   9506  N N   . ALA C 1 299 ? 146.440 116.470 105.905 1.00 13.73 ? 278  ALA C N   1 
ATOM   9507  C CA  . ALA C 1 299 ? 147.736 116.728 105.298 1.00 13.73 ? 278  ALA C CA  1 
ATOM   9508  C C   . ALA C 1 299 ? 148.624 115.493 105.231 1.00 13.73 ? 278  ALA C C   1 
ATOM   9509  O O   . ALA C 1 299 ? 149.845 115.617 105.360 1.00 13.73 ? 278  ALA C O   1 
ATOM   9510  C CB  . ALA C 1 299 ? 148.454 117.845 106.054 1.00 13.73 ? 278  ALA C CB  1 
ATOM   9511  N N   . ARG C 1 300 ? 148.048 114.304 105.048 1.00 16.30 ? 279  ARG C N   1 
ATOM   9512  C CA  . ARG C 1 300 ? 148.877 113.125 104.831 1.00 16.30 ? 279  ARG C CA  1 
ATOM   9513  C C   . ARG C 1 300 ? 149.569 113.184 103.478 1.00 16.30 ? 279  ARG C C   1 
ATOM   9514  O O   . ARG C 1 300 ? 150.775 112.935 103.372 1.00 16.30 ? 279  ARG C O   1 
ATOM   9515  C CB  . ARG C 1 300 ? 148.040 111.852 104.950 1.00 16.30 ? 279  ARG C CB  1 
ATOM   9516  C CG  . ARG C 1 300 ? 147.769 111.416 106.379 1.00 16.30 ? 279  ARG C CG  1 
ATOM   9517  C CD  . ARG C 1 300 ? 146.751 110.295 106.426 1.00 16.30 ? 279  ARG C CD  1 
ATOM   9518  N NE  . ARG C 1 300 ? 146.116 110.206 107.735 1.00 16.30 ? 279  ARG C NE  1 
ATOM   9519  C CZ  . ARG C 1 300 ? 144.997 109.536 107.982 1.00 16.30 ? 279  ARG C CZ  1 
ATOM   9520  N NH1 . ARG C 1 300 ? 144.382 108.886 107.008 1.00 16.30 ? 279  ARG C NH1 1 
ATOM   9521  N NH2 . ARG C 1 300 ? 144.497 109.515 109.209 1.00 16.30 ? 279  ARG C NH2 1 
ATOM   9522  N N   . GLU C 1 301 ? 148.824 113.520 102.427 1.00 21.76 ? 280  GLU C N   1 
ATOM   9523  C CA  . GLU C 1 301 ? 149.381 113.564 101.084 1.00 21.76 ? 280  GLU C CA  1 
ATOM   9524  C C   . GLU C 1 301 ? 148.832 114.758 100.317 1.00 21.76 ? 280  GLU C C   1 
ATOM   9525  O O   . GLU C 1 301 ? 147.770 115.294 100.639 1.00 21.76 ? 280  GLU C O   1 
ATOM   9526  C CB  . GLU C 1 301 ? 149.098 112.274 100.303 1.00 21.76 ? 280  GLU C CB  1 
ATOM   9527  C CG  . GLU C 1 301 ? 150.038 111.125 100.620 1.00 21.76 ? 280  GLU C CG  1 
ATOM   9528  C CD  . GLU C 1 301 ? 149.592 110.302 101.806 1.00 21.76 ? 280  GLU C CD  1 
ATOM   9529  O OE1 . GLU C 1 301 ? 150.351 110.218 102.793 1.00 21.76 ? 280  GLU C OE1 1 
ATOM   9530  O OE2 . GLU C 1 301 ? 148.484 109.730 101.748 1.00 21.76 ? 280  GLU C OE2 1 
ATOM   9531  N N   . ASP C 1 302 ? 149.588 115.168 99.299  1.00 22.40 ? 281  ASP C N   1 
ATOM   9532  C CA  . ASP C 1 302 ? 149.227 116.280 98.418  1.00 22.40 ? 281  ASP C CA  1 
ATOM   9533  C C   . ASP C 1 302 ? 148.643 115.732 97.116  1.00 22.40 ? 281  ASP C C   1 
ATOM   9534  O O   . ASP C 1 302 ? 149.211 115.876 96.032  1.00 22.40 ? 281  ASP C O   1 
ATOM   9535  C CB  . ASP C 1 302 ? 150.452 117.151 98.154  1.00 22.40 ? 281  ASP C CB  1 
ATOM   9536  C CG  . ASP C 1 302 ? 150.137 118.405 97.345  1.00 22.40 ? 281  ASP C CG  1 
ATOM   9537  O OD1 . ASP C 1 302 ? 148.976 118.594 96.931  1.00 22.40 ? 281  ASP C OD1 1 
ATOM   9538  O OD2 . ASP C 1 302 ? 151.068 119.200 97.106  1.00 22.40 ? 281  ASP C OD2 1 
ATOM   9539  N N   . ASP C 1 303 ? 147.481 115.083 97.225  1.00 21.81 ? 282  ASP C N   1 
ATOM   9540  C CA  . ASP C 1 303 ? 146.891 114.462 96.042  1.00 21.81 ? 282  ASP C CA  1 
ATOM   9541  C C   . ASP C 1 303 ? 145.568 115.093 95.626  1.00 21.81 ? 282  ASP C C   1 
ATOM   9542  O O   . ASP C 1 303 ? 145.522 115.765 94.595  1.00 21.81 ? 282  ASP C O   1 
ATOM   9543  C CB  . ASP C 1 303 ? 146.728 112.963 96.303  1.00 21.81 ? 282  ASP C CB  1 
ATOM   9544  C CG  . ASP C 1 303 ? 146.048 112.673 97.630  1.00 21.81 ? 282  ASP C CG  1 
ATOM   9545  O OD1 . ASP C 1 303 ? 145.826 113.626 98.408  1.00 21.81 ? 282  ASP C OD1 1 
ATOM   9546  O OD2 . ASP C 1 303 ? 145.732 111.494 97.893  1.00 21.81 ? 282  ASP C OD2 1 
ATOM   9547  N N   . ASP C 1 304 ? 144.494 114.922 96.392  1.00 17.78 ? 283  ASP C N   1 
ATOM   9548  C CA  . ASP C 1 304 ? 143.217 115.489 95.978  1.00 17.78 ? 283  ASP C CA  1 
ATOM   9549  C C   . ASP C 1 304 ? 142.370 115.991 97.140  1.00 17.78 ? 283  ASP C C   1 
ATOM   9550  O O   . ASP C 1 304 ? 141.557 116.903 96.972  1.00 17.78 ? 283  ASP C O   1 
ATOM   9551  C CB  . ASP C 1 304 ? 142.467 114.462 95.121  1.00 17.78 ? 283  ASP C CB  1 
ATOM   9552  C CG  . ASP C 1 304 ? 142.138 113.187 95.875  1.00 17.78 ? 283  ASP C CG  1 
ATOM   9553  O OD1 . ASP C 1 304 ? 142.515 113.061 97.058  1.00 17.78 ? 283  ASP C OD1 1 
ATOM   9554  O OD2 . ASP C 1 304 ? 141.533 112.283 95.262  1.00 17.78 ? 283  ASP C OD2 1 
ATOM   9555  N N   . PHE C 1 305 ? 142.559 115.417 98.326  1.00 9.50  ? 284  PHE C N   1 
ATOM   9556  C CA  . PHE C 1 305 ? 141.804 115.876 99.481  1.00 9.50  ? 284  PHE C CA  1 
ATOM   9557  C C   . PHE C 1 305 ? 142.434 117.090 100.134 1.00 9.50  ? 284  PHE C C   1 
ATOM   9558  O O   . PHE C 1 305 ? 141.727 117.869 100.774 1.00 9.50  ? 284  PHE C O   1 
ATOM   9559  C CB  . PHE C 1 305 ? 141.665 114.763 100.515 1.00 9.50  ? 284  PHE C CB  1 
ATOM   9560  C CG  . PHE C 1 305 ? 140.837 115.151 101.703 1.00 9.50  ? 284  PHE C CG  1 
ATOM   9561  C CD1 . PHE C 1 305 ? 139.526 115.546 101.548 1.00 9.50  ? 284  PHE C CD1 1 
ATOM   9562  C CD2 . PHE C 1 305 ? 141.377 115.140 102.970 1.00 9.50  ? 284  PHE C CD2 1 
ATOM   9563  C CE1 . PHE C 1 305 ? 138.776 115.911 102.633 1.00 9.50  ? 284  PHE C CE1 1 
ATOM   9564  C CE2 . PHE C 1 305 ? 140.625 115.500 104.052 1.00 9.50  ? 284  PHE C CE2 1 
ATOM   9565  C CZ  . PHE C 1 305 ? 139.326 115.887 103.883 1.00 9.50  ? 284  PHE C CZ  1 
ATOM   9566  N N   . PHE C 1 306 ? 143.741 117.279 99.978  1.00 12.76 ? 285  PHE C N   1 
ATOM   9567  C CA  . PHE C 1 306 ? 144.363 118.486 100.501 1.00 12.76 ? 285  PHE C CA  1 
ATOM   9568  C C   . PHE C 1 306 ? 144.070 119.679 99.600  1.00 12.76 ? 285  PHE C C   1 
ATOM   9569  O O   . PHE C 1 306 ? 143.863 120.794 100.089 1.00 12.76 ? 285  PHE C O   1 
ATOM   9570  C CB  . PHE C 1 306 ? 145.864 118.254 100.671 1.00 12.76 ? 285  PHE C CB  1 
ATOM   9571  C CG  . PHE C 1 306 ? 146.583 119.379 101.348 1.00 12.76 ? 285  PHE C CG  1 
ATOM   9572  C CD1 . PHE C 1 306 ? 146.402 119.615 102.694 1.00 12.76 ? 285  PHE C CD1 1 
ATOM   9573  C CD2 . PHE C 1 306 ? 147.477 120.170 100.650 1.00 12.76 ? 285  PHE C CD2 1 
ATOM   9574  C CE1 . PHE C 1 306 ? 147.070 120.637 103.324 1.00 12.76 ? 285  PHE C CE1 1 
ATOM   9575  C CE2 . PHE C 1 306 ? 148.151 121.193 101.279 1.00 12.76 ? 285  PHE C CE2 1 
ATOM   9576  C CZ  . PHE C 1 306 ? 147.947 121.426 102.617 1.00 12.76 ? 285  PHE C CZ  1 
ATOM   9577  N N   . ASP C 1 307 ? 144.019 119.459 98.285  1.00 14.07 ? 286  ASP C N   1 
ATOM   9578  C CA  . ASP C 1 307 ? 143.555 120.506 97.382  1.00 14.07 ? 286  ASP C CA  1 
ATOM   9579  C C   . ASP C 1 307 ? 142.128 120.912 97.715  1.00 14.07 ? 286  ASP C C   1 
ATOM   9580  O O   . ASP C 1 307 ? 141.807 122.105 97.769  1.00 14.07 ? 286  ASP C O   1 
ATOM   9581  C CB  . ASP C 1 307 ? 143.651 120.029 95.934  1.00 14.07 ? 286  ASP C CB  1 
ATOM   9582  C CG  . ASP C 1 307 ? 143.869 121.167 94.952  1.00 14.07 ? 286  ASP C CG  1 
ATOM   9583  O OD1 . ASP C 1 307 ? 144.011 122.323 95.397  1.00 14.07 ? 286  ASP C OD1 1 
ATOM   9584  O OD2 . ASP C 1 307 ? 143.901 120.906 93.730  1.00 14.07 ? 286  ASP C OD2 1 
ATOM   9585  N N   . LYS C 1 308 ? 141.258 119.928 97.951  1.00 10.54 ? 287  LYS C N   1 
ATOM   9586  C CA  . LYS C 1 308 ? 139.891 120.219 98.359  1.00 10.54 ? 287  LYS C CA  1 
ATOM   9587  C C   . LYS C 1 308 ? 139.849 120.917 99.706  1.00 10.54 ? 287  LYS C C   1 
ATOM   9588  O O   . LYS C 1 308 ? 138.994 121.776 99.931  1.00 10.54 ? 287  LYS C O   1 
ATOM   9589  C CB  . LYS C 1 308 ? 139.076 118.930 98.406  1.00 10.54 ? 287  LYS C CB  1 
ATOM   9590  C CG  . LYS C 1 308 ? 137.589 119.133 98.205  1.00 10.54 ? 287  LYS C CG  1 
ATOM   9591  C CD  . LYS C 1 308 ? 136.818 117.852 98.437  1.00 10.54 ? 287  LYS C CD  1 
ATOM   9592  C CE  . LYS C 1 308 ? 135.370 118.148 98.794  1.00 10.54 ? 287  LYS C CE  1 
ATOM   9593  N NZ  . LYS C 1 308 ? 134.478 118.154 97.605  1.00 10.54 ? 287  LYS C NZ  1 
ATOM   9594  N N   . ALA C 1 309 ? 140.761 120.568 100.611 1.00 9.49  ? 288  ALA C N   1 
ATOM   9595  C CA  . ALA C 1 309 ? 140.797 121.214 101.918 1.00 9.49  ? 288  ALA C CA  1 
ATOM   9596  C C   . ALA C 1 309 ? 141.149 122.690 101.790 1.00 9.49  ? 288  ALA C C   1 
ATOM   9597  O O   . ALA C 1 309 ? 140.511 123.548 102.408 1.00 9.49  ? 288  ALA C O   1 
ATOM   9598  C CB  . ALA C 1 309 ? 141.792 120.492 102.824 1.00 9.49  ? 288  ALA C CB  1 
ATOM   9599  N N   . LEU C 1 310 ? 142.167 123.003 100.990 1.00 11.65 ? 289  LEU C N   1 
ATOM   9600  C CA  . LEU C 1 310 ? 142.519 124.400 100.757 1.00 11.65 ? 289  LEU C CA  1 
ATOM   9601  C C   . LEU C 1 310 ? 141.385 125.141 100.064 1.00 11.65 ? 289  LEU C C   1 
ATOM   9602  O O   . LEU C 1 310 ? 141.021 126.254 100.459 1.00 11.65 ? 289  LEU C O   1 
ATOM   9603  C CB  . LEU C 1 310 ? 143.799 124.490 99.931  1.00 11.65 ? 289  LEU C CB  1 
ATOM   9604  C CG  . LEU C 1 310 ? 144.983 123.704 100.482 1.00 11.65 ? 289  LEU C CG  1 
ATOM   9605  C CD1 . LEU C 1 310 ? 145.953 123.345 99.373  1.00 11.65 ? 289  LEU C CD1 1 
ATOM   9606  C CD2 . LEU C 1 310 ? 145.663 124.503 101.563 1.00 11.65 ? 289  LEU C CD2 1 
ATOM   9607  N N   . GLU C 1 311 ? 140.810 124.532 99.025  1.00 11.75 ? 290  GLU C N   1 
ATOM   9608  C CA  . GLU C 1 311 ? 139.709 125.156 98.302  1.00 11.75 ? 290  GLU C CA  1 
ATOM   9609  C C   . GLU C 1 311 ? 138.508 125.402 99.208  1.00 11.75 ? 290  GLU C C   1 
ATOM   9610  O O   . GLU C 1 311 ? 137.767 126.369 99.005  1.00 11.75 ? 290  GLU C O   1 
ATOM   9611  C CB  . GLU C 1 311 ? 139.334 124.275 97.109  1.00 11.75 ? 290  GLU C CB  1 
ATOM   9612  C CG  . GLU C 1 311 ? 138.222 124.797 96.218  1.00 11.75 ? 290  GLU C CG  1 
ATOM   9613  C CD  . GLU C 1 311 ? 136.844 124.448 96.728  1.00 11.75 ? 290  GLU C CD  1 
ATOM   9614  O OE1 . GLU C 1 311 ? 136.070 125.382 96.998  1.00 11.75 ? 290  GLU C OE1 1 
ATOM   9615  O OE2 . GLU C 1 311 ? 136.537 123.246 96.866  1.00 11.75 ? 290  GLU C OE2 1 
ATOM   9616  N N   . GLY C 1 312 ? 138.298 124.549 100.208 1.00 9.50  ? 291  GLY C N   1 
ATOM   9617  C CA  . GLY C 1 312 ? 137.274 124.782 101.203 1.00 9.50  ? 291  GLY C CA  1 
ATOM   9618  C C   . GLY C 1 312 ? 137.673 125.723 102.305 1.00 9.50  ? 291  GLY C C   1 
ATOM   9619  O O   . GLY C 1 312 ? 136.811 126.192 103.050 1.00 9.50  ? 291  GLY C O   1 
ATOM   9620  N N   . PHE C 1 313 ? 138.972 126.000 102.440 1.00 10.52 ? 292  PHE C N   1 
ATOM   9621  C CA  . PHE C 1 313 ? 139.419 127.055 103.344 1.00 10.52 ? 292  PHE C CA  1 
ATOM   9622  C C   . PHE C 1 313 ? 139.066 128.427 102.788 1.00 10.52 ? 292  PHE C C   1 
ATOM   9623  O O   . PHE C 1 313 ? 138.627 129.312 103.530 1.00 10.52 ? 292  PHE C O   1 
ATOM   9624  C CB  . PHE C 1 313 ? 140.927 126.944 103.579 1.00 10.52 ? 292  PHE C CB  1 
ATOM   9625  C CG  . PHE C 1 313 ? 141.564 128.213 104.073 1.00 10.52 ? 292  PHE C CG  1 
ATOM   9626  C CD1 . PHE C 1 313 ? 141.495 128.562 105.406 1.00 10.52 ? 292  PHE C CD1 1 
ATOM   9627  C CD2 . PHE C 1 313 ? 142.232 129.057 103.205 1.00 10.52 ? 292  PHE C CD2 1 
ATOM   9628  C CE1 . PHE C 1 313 ? 142.077 129.725 105.862 1.00 10.52 ? 292  PHE C CE1 1 
ATOM   9629  C CE2 . PHE C 1 313 ? 142.807 130.223 103.660 1.00 10.52 ? 292  PHE C CE2 1 
ATOM   9630  C CZ  . PHE C 1 313 ? 142.732 130.553 104.988 1.00 10.52 ? 292  PHE C CZ  1 
ATOM   9631  N N   . THR C 1 314 ? 139.247 128.617 101.480 1.00 11.10 ? 293  THR C N   1 
ATOM   9632  C CA  . THR C 1 314 ? 138.933 129.878 100.815 1.00 11.10 ? 293  THR C CA  1 
ATOM   9633  C C   . THR C 1 314 ? 137.437 129.951 100.506 1.00 11.10 ? 293  THR C C   1 
ATOM   9634  O O   . THR C 1 314 ? 137.006 130.080 99.361  1.00 11.10 ? 293  THR C O   1 
ATOM   9635  C CB  . THR C 1 314 ? 139.756 130.023 99.544  1.00 11.10 ? 293  THR C CB  1 
ATOM   9636  O OG1 . THR C 1 314 ? 139.391 128.993 98.622  1.00 11.10 ? 293  THR C OG1 1 
ATOM   9637  C CG2 . THR C 1 314 ? 141.222 129.874 99.861  1.00 11.10 ? 293  THR C CG2 1 
ATOM   9638  N N   . MET C 1 315 ? 136.638 129.858 101.565 1.00 13.64 ? 294  MET C N   1 
ATOM   9639  C CA  . MET C 1 315 ? 135.191 129.908 101.450 1.00 13.64 ? 294  MET C CA  1 
ATOM   9640  C C   . MET C 1 315 ? 134.595 131.154 102.077 1.00 13.64 ? 294  MET C C   1 
ATOM   9641  O O   . MET C 1 315 ? 133.389 131.383 101.939 1.00 13.64 ? 294  MET C O   1 
ATOM   9642  C CB  . MET C 1 315 ? 134.562 128.664 102.080 1.00 13.64 ? 294  MET C CB  1 
ATOM   9643  C CG  . MET C 1 315 ? 134.399 127.497 101.131 1.00 13.64 ? 294  MET C CG  1 
ATOM   9644  S SD  . MET C 1 315 ? 133.736 128.013 99.542  1.00 13.64 ? 294  MET C SD  1 
ATOM   9645  C CE  . MET C 1 315 ? 133.731 126.461 98.662  1.00 13.64 ? 294  MET C CE  1 
ATOM   9646  N N   . PHE C 1 316 ? 135.398 131.954 102.774 1.00 15.03 ? 295  PHE C N   1 
ATOM   9647  C CA  . PHE C 1 316 ? 134.960 133.287 103.160 1.00 15.03 ? 295  PHE C CA  1 
ATOM   9648  C C   . PHE C 1 316 ? 134.824 134.199 101.949 1.00 15.03 ? 295  PHE C C   1 
ATOM   9649  O O   . PHE C 1 316 ? 134.054 135.161 101.993 1.00 15.03 ? 295  PHE C O   1 
ATOM   9650  C CB  . PHE C 1 316 ? 135.944 133.891 104.169 1.00 15.03 ? 295  PHE C CB  1 
ATOM   9651  C CG  . PHE C 1 316 ? 137.346 134.046 103.631 1.00 15.03 ? 295  PHE C CG  1 
ATOM   9652  C CD1 . PHE C 1 316 ? 138.204 132.963 103.559 1.00 15.03 ? 295  PHE C CD1 1 
ATOM   9653  C CD2 . PHE C 1 316 ? 137.798 135.276 103.188 1.00 15.03 ? 295  PHE C CD2 1 
ATOM   9654  C CE1 . PHE C 1 316 ? 139.476 133.107 103.057 1.00 15.03 ? 295  PHE C CE1 1 
ATOM   9655  C CE2 . PHE C 1 316 ? 139.072 135.421 102.689 1.00 15.03 ? 295  PHE C CE2 1 
ATOM   9656  C CZ  . PHE C 1 316 ? 139.910 134.339 102.623 1.00 15.03 ? 295  PHE C CZ  1 
ATOM   9657  N N   . ALA C 1 317 ? 135.539 133.897 100.865 1.00 15.87 ? 296  ALA C N   1 
ATOM   9658  C CA  . ALA C 1 317 ? 135.610 134.744 99.684  1.00 15.87 ? 296  ALA C CA  1 
ATOM   9659  C C   . ALA C 1 317 ? 134.646 134.309 98.587  1.00 15.87 ? 296  ALA C C   1 
ATOM   9660  O O   . ALA C 1 317 ? 134.779 134.751 97.442  1.00 15.87 ? 296  ALA C O   1 
ATOM   9661  C CB  . ALA C 1 317 ? 137.039 134.773 99.146  1.00 15.87 ? 296  ALA C CB  1 
ATOM   9662  N N   . LEU C 1 318 ? 133.691 133.442 98.906  1.00 18.25 ? 297  LEU C N   1 
ATOM   9663  C CA  . LEU C 1 318 ? 132.604 133.107 97.998  1.00 18.25 ? 297  LEU C CA  1 
ATOM   9664  C C   . LEU C 1 318 ? 131.373 133.882 98.442  1.00 18.25 ? 297  LEU C C   1 
ATOM   9665  O O   . LEU C 1 318 ? 130.959 133.777 99.601  1.00 18.25 ? 297  LEU C O   1 
ATOM   9666  C CB  . LEU C 1 318 ? 132.328 131.604 97.993  1.00 18.25 ? 297  LEU C CB  1 
ATOM   9667  C CG  . LEU C 1 318 ? 131.282 131.112 96.990  1.00 18.25 ? 297  LEU C CG  1 
ATOM   9668  C CD1 . LEU C 1 318 ? 131.718 129.796 96.368  1.00 18.25 ? 297  LEU C CD1 1 
ATOM   9669  C CD2 . LEU C 1 318 ? 129.923 130.960 97.656  1.00 18.25 ? 297  LEU C CD2 1 
ATOM   9670  N N   . ASN C 1 319 ? 130.796 134.657 97.520  1.00 18.87 ? 298  ASN C N   1 
ATOM   9671  C CA  . ASN C 1 319 ? 129.680 135.553 97.827  1.00 18.87 ? 298  ASN C CA  1 
ATOM   9672  C C   . ASN C 1 319 ? 130.063 136.522 98.949  1.00 18.87 ? 298  ASN C C   1 
ATOM   9673  O O   . ASN C 1 319 ? 129.260 136.849 99.824  1.00 18.87 ? 298  ASN C O   1 
ATOM   9674  C CB  . ASN C 1 319 ? 128.413 134.758 98.167  1.00 18.87 ? 298  ASN C CB  1 
ATOM   9675  C CG  . ASN C 1 319 ? 127.213 135.643 98.456  1.00 18.87 ? 298  ASN C CG  1 
ATOM   9676  O OD1 . ASN C 1 319 ? 126.736 136.366 97.587  1.00 18.87 ? 298  ASN C OD1 1 
ATOM   9677  N ND2 . ASN C 1 319 ? 126.729 135.593 99.690  1.00 18.87 ? 298  ASN C ND2 1 
ATOM   9678  N N   . GLN C 1 320 ? 131.332 136.942 98.941  1.00 17.65 ? 299  GLN C N   1 
ATOM   9679  C CA  . GLN C 1 320 ? 131.832 138.070 99.735  1.00 17.65 ? 299  GLN C CA  1 
ATOM   9680  C C   . GLN C 1 320 ? 131.466 137.949 101.213 1.00 17.65 ? 299  GLN C C   1 
ATOM   9681  O O   . GLN C 1 320 ? 131.184 138.941 101.884 1.00 17.65 ? 299  GLN C O   1 
ATOM   9682  C CB  . GLN C 1 320 ? 131.326 139.398 99.175  1.00 17.65 ? 299  GLN C CB  1 
ATOM   9683  C CG  . GLN C 1 320 ? 131.821 139.719 97.791  1.00 17.65 ? 299  GLN C CG  1 
ATOM   9684  C CD  . GLN C 1 320 ? 131.115 138.914 96.725  1.00 17.65 ? 299  GLN C CD  1 
ATOM   9685  O OE1 . GLN C 1 320 ? 131.730 138.118 96.020  1.00 17.65 ? 299  GLN C OE1 1 
ATOM   9686  N NE2 . GLN C 1 320 ? 129.813 139.124 96.597  1.00 17.65 ? 299  GLN C NE2 1 
ATOM   9687  N N   . GLY C 1 321 ? 131.454 136.722 101.721 1.00 19.47 ? 300  GLY C N   1 
ATOM   9688  C CA  . GLY C 1 321 ? 131.305 136.488 103.143 1.00 19.47 ? 300  GLY C CA  1 
ATOM   9689  C C   . GLY C 1 321 ? 130.080 137.060 103.827 1.00 19.47 ? 300  GLY C C   1 
ATOM   9690  O O   . GLY C 1 321 ? 130.000 137.028 105.057 1.00 19.47 ? 300  GLY C O   1 
ATOM   9691  N N   . GLU C 1 322 ? 129.115 137.586 103.069 1.00 20.97 ? 301  GLU C N   1 
ATOM   9692  C CA  . GLU C 1 322 ? 127.881 138.029 103.708 1.00 20.97 ? 301  GLU C CA  1 
ATOM   9693  C C   . GLU C 1 322 ? 127.007 136.866 104.154 1.00 20.97 ? 301  GLU C C   1 
ATOM   9694  O O   . GLU C 1 322 ? 126.001 137.100 104.833 1.00 20.97 ? 301  GLU C O   1 
ATOM   9695  C CB  . GLU C 1 322 ? 127.070 138.942 102.786 1.00 20.97 ? 301  GLU C CB  1 
ATOM   9696  C CG  . GLU C 1 322 ? 127.715 140.285 102.462 1.00 20.97 ? 301  GLU C CG  1 
ATOM   9697  C CD  . GLU C 1 322 ? 128.441 140.291 101.131 1.00 20.97 ? 301  GLU C CD  1 
ATOM   9698  O OE1 . GLU C 1 322 ? 128.411 139.265 100.430 1.00 20.97 ? 301  GLU C OE1 1 
ATOM   9699  O OE2 . GLU C 1 322 ? 129.036 141.329 100.782 1.00 20.97 ? 301  GLU C OE2 1 
ATOM   9700  N N   . VAL C 1 323 ? 127.360 135.634 103.779 1.00 19.39 ? 302  VAL C N   1 
ATOM   9701  C CA  . VAL C 1 323 ? 126.578 134.466 104.161 1.00 19.39 ? 302  VAL C CA  1 
ATOM   9702  C C   . VAL C 1 323 ? 126.485 134.388 105.677 1.00 19.39 ? 302  VAL C C   1 
ATOM   9703  O O   . VAL C 1 323 ? 127.460 134.645 106.393 1.00 19.39 ? 302  VAL C O   1 
ATOM   9704  C CB  . VAL C 1 323 ? 127.221 133.194 103.584 1.00 19.39 ? 302  VAL C CB  1 
ATOM   9705  C CG1 . VAL C 1 323 ? 126.415 131.967 103.957 1.00 19.39 ? 302  VAL C CG1 1 
ATOM   9706  C CG2 . VAL C 1 323 ? 127.389 133.309 102.080 1.00 19.39 ? 302  VAL C CG2 1 
ATOM   9707  N N   . CYS C 1 324 ? 125.301 134.032 106.180 1.00 25.03 ? 303  CYS C N   1 
ATOM   9708  C CA  . CYS C 1 324 ? 125.122 133.948 107.625 1.00 25.03 ? 303  CYS C CA  1 
ATOM   9709  C C   . CYS C 1 324 ? 125.937 132.813 108.232 1.00 25.03 ? 303  CYS C C   1 
ATOM   9710  O O   . CYS C 1 324 ? 126.289 132.870 109.415 1.00 25.03 ? 303  CYS C O   1 
ATOM   9711  C CB  . CYS C 1 324 ? 123.642 133.786 107.964 1.00 25.03 ? 303  CYS C CB  1 
ATOM   9712  S SG  . CYS C 1 324 ? 122.677 135.303 107.843 1.00 25.03 ? 303  CYS C SG  1 
ATOM   9713  N N   . THR C 1 325 ? 126.244 131.781 107.447 1.00 17.41 ? 304  THR C N   1 
ATOM   9714  C CA  . THR C 1 325 ? 127.087 130.665 107.878 1.00 17.41 ? 304  THR C CA  1 
ATOM   9715  C C   . THR C 1 325 ? 128.510 130.807 107.377 1.00 17.41 ? 304  THR C C   1 
ATOM   9716  O O   . THR C 1 325 ? 129.141 129.815 107.008 1.00 17.41 ? 304  THR C O   1 
ATOM   9717  C CB  . THR C 1 325 ? 126.492 129.342 107.411 1.00 17.41 ? 304  THR C CB  1 
ATOM   9718  O OG1 . THR C 1 325 ? 125.824 129.534 106.158 1.00 17.41 ? 304  THR C OG1 1 
ATOM   9719  C CG2 . THR C 1 325 ? 125.507 128.802 108.432 1.00 17.41 ? 304  THR C CG2 1 
ATOM   9720  N N   . CYS C 1 326 ? 129.028 132.025 107.328 1.00 17.38 ? 305  CYS C N   1 
ATOM   9721  C CA  . CYS C 1 326 ? 130.346 132.270 106.764 1.00 17.38 ? 305  CYS C CA  1 
ATOM   9722  C C   . CYS C 1 326 ? 131.412 131.500 107.533 1.00 17.38 ? 305  CYS C C   1 
ATOM   9723  O O   . CYS C 1 326 ? 131.459 131.588 108.769 1.00 17.38 ? 305  CYS C O   1 
ATOM   9724  C CB  . CYS C 1 326 ? 130.661 133.763 106.785 1.00 17.38 ? 305  CYS C CB  1 
ATOM   9725  S SG  . CYS C 1 326 ? 130.349 134.569 108.369 1.00 17.38 ? 305  CYS C SG  1 
ATOM   9726  N N   . PRO C 1 327 ? 132.277 130.742 106.855 1.00 12.38 ? 306  PRO C N   1 
ATOM   9727  C CA  . PRO C 1 327 ? 133.402 130.043 107.507 1.00 12.38 ? 306  PRO C CA  1 
ATOM   9728  C C   . PRO C 1 327 ? 134.555 130.997 107.786 1.00 12.38 ? 306  PRO C C   1 
ATOM   9729  O O   . PRO C 1 327 ? 135.648 130.906 107.222 1.00 12.38 ? 306  PRO C O   1 
ATOM   9730  C CB  . PRO C 1 327 ? 133.763 128.967 106.480 1.00 12.38 ? 306  PRO C CB  1 
ATOM   9731  C CG  . PRO C 1 327 ? 133.124 129.390 105.187 1.00 12.38 ? 306  PRO C CG  1 
ATOM   9732  C CD  . PRO C 1 327 ? 132.338 130.630 105.393 1.00 12.38 ? 306  PRO C CD  1 
ATOM   9733  N N   . SER C 1 328 ? 134.307 131.951 108.682 1.00 12.97 ? 307  SER C N   1 
ATOM   9734  C CA  . SER C 1 328 ? 135.235 133.038 108.958 1.00 12.97 ? 307  SER C CA  1 
ATOM   9735  C C   . SER C 1 328 ? 136.082 132.779 110.196 1.00 12.97 ? 307  SER C C   1 
ATOM   9736  O O   . SER C 1 328 ? 136.482 133.722 110.884 1.00 12.97 ? 307  SER C O   1 
ATOM   9737  C CB  . SER C 1 328 ? 134.464 134.345 109.105 1.00 12.97 ? 307  SER C CB  1 
ATOM   9738  O OG  . SER C 1 328 ? 133.403 134.190 110.027 1.00 12.97 ? 307  SER C OG  1 
ATOM   9739  N N   . ARG C 1 329 ? 136.356 131.509 110.496 1.00 10.98 ? 308  ARG C N   1 
ATOM   9740  C CA  . ARG C 1 329 ? 137.143 131.150 111.671 1.00 10.98 ? 308  ARG C CA  1 
ATOM   9741  C C   . ARG C 1 329 ? 137.768 129.783 111.389 1.00 10.98 ? 308  ARG C C   1 
ATOM   9742  O O   . ARG C 1 329 ? 137.085 128.764 111.485 1.00 10.98 ? 308  ARG C O   1 
ATOM   9743  C CB  . ARG C 1 329 ? 136.268 131.134 112.912 1.00 10.98 ? 308  ARG C CB  1 
ATOM   9744  C CG  . ARG C 1 329 ? 137.018 130.991 114.203 1.00 10.98 ? 308  ARG C CG  1 
ATOM   9745  C CD  . ARG C 1 329 ? 136.147 131.379 115.372 1.00 10.98 ? 308  ARG C CD  1 
ATOM   9746  N NE  . ARG C 1 329 ? 135.066 130.430 115.610 1.00 10.98 ? 308  ARG C NE  1 
ATOM   9747  C CZ  . ARG C 1 329 ? 134.236 130.504 116.644 1.00 10.98 ? 308  ARG C CZ  1 
ATOM   9748  N NH1 . ARG C 1 329 ? 134.375 131.477 117.531 1.00 10.98 ? 308  ARG C NH1 1 
ATOM   9749  N NH2 . ARG C 1 329 ? 133.275 129.607 116.798 1.00 10.98 ? 308  ARG C NH2 1 
ATOM   9750  N N   . VAL C 1 330 ? 139.051 129.770 111.049 1.00 7.65  ? 309  VAL C N   1 
ATOM   9751  C CA  . VAL C 1 330 ? 139.722 128.571 110.560 1.00 7.65  ? 309  VAL C CA  1 
ATOM   9752  C C   . VAL C 1 330 ? 140.689 128.068 111.621 1.00 7.65  ? 309  VAL C C   1 
ATOM   9753  O O   . VAL C 1 330 ? 141.626 128.776 112.005 1.00 7.65  ? 309  VAL C O   1 
ATOM   9754  C CB  . VAL C 1 330 ? 140.447 128.835 109.236 1.00 7.65  ? 309  VAL C CB  1 
ATOM   9755  C CG1 . VAL C 1 330 ? 141.284 127.642 108.855 1.00 7.65  ? 309  VAL C CG1 1 
ATOM   9756  C CG2 . VAL C 1 330 ? 139.437 129.120 108.156 1.00 7.65  ? 309  VAL C CG2 1 
ATOM   9757  N N   . LEU C 1 331 ? 140.472 126.836 112.075 1.00 5.81  ? 310  LEU C N   1 
ATOM   9758  C CA  . LEU C 1 331 ? 141.297 126.180 113.086 1.00 5.81  ? 310  LEU C CA  1 
ATOM   9759  C C   . LEU C 1 331 ? 142.162 125.146 112.383 1.00 5.81  ? 310  LEU C C   1 
ATOM   9760  O O   . LEU C 1 331 ? 141.646 124.144 111.883 1.00 5.81  ? 310  LEU C O   1 
ATOM   9761  C CB  . LEU C 1 331 ? 140.433 125.510 114.150 1.00 5.81  ? 310  LEU C CB  1 
ATOM   9762  C CG  . LEU C 1 331 ? 139.625 126.307 115.172 1.00 5.81  ? 310  LEU C CG  1 
ATOM   9763  C CD1 . LEU C 1 331 ? 138.573 127.169 114.526 1.00 5.81  ? 310  LEU C CD1 1 
ATOM   9764  C CD2 . LEU C 1 331 ? 138.981 125.343 116.131 1.00 5.81  ? 310  LEU C CD2 1 
ATOM   9765  N N   . ILE C 1 332 ? 143.468 125.377 112.342 1.00 8.97  ? 311  ILE C N   1 
ATOM   9766  C CA  . ILE C 1 332 ? 144.394 124.480 111.662 1.00 8.97  ? 311  ILE C CA  1 
ATOM   9767  C C   . ILE C 1 332 ? 145.271 123.797 112.697 1.00 8.97  ? 311  ILE C C   1 
ATOM   9768  O O   . ILE C 1 332 ? 145.736 124.431 113.650 1.00 8.97  ? 311  ILE C O   1 
ATOM   9769  C CB  . ILE C 1 332 ? 145.251 125.220 110.621 1.00 8.97  ? 311  ILE C CB  1 
ATOM   9770  C CG1 . ILE C 1 332 ? 144.359 126.033 109.695 1.00 8.97  ? 311  ILE C CG1 1 
ATOM   9771  C CG2 . ILE C 1 332 ? 146.052 124.238 109.800 1.00 8.97  ? 311  ILE C CG2 1 
ATOM   9772  C CD1 . ILE C 1 332 ? 145.099 127.076 108.938 1.00 8.97  ? 311  ILE C CD1 1 
ATOM   9773  N N   . GLN C 1 333 ? 145.483 122.497 112.513 1.00 14.01 ? 312  GLN C N   1 
ATOM   9774  C CA  . GLN C 1 333 ? 146.302 121.731 113.439 1.00 14.01 ? 312  GLN C CA  1 
ATOM   9775  C C   . GLN C 1 333 ? 147.729 122.261 113.458 1.00 14.01 ? 312  GLN C C   1 
ATOM   9776  O O   . GLN C 1 333 ? 148.292 122.611 112.418 1.00 14.01 ? 312  GLN C O   1 
ATOM   9777  C CB  . GLN C 1 333 ? 146.295 120.259 113.043 1.00 14.01 ? 312  GLN C CB  1 
ATOM   9778  C CG  . GLN C 1 333 ? 147.264 119.410 113.829 1.00 14.01 ? 312  GLN C CG  1 
ATOM   9779  C CD  . GLN C 1 333 ? 146.640 118.804 115.058 1.00 14.01 ? 312  GLN C CD  1 
ATOM   9780  O OE1 . GLN C 1 333 ? 145.426 118.626 115.128 1.00 14.01 ? 312  GLN C OE1 1 
ATOM   9781  N NE2 . GLN C 1 333 ? 147.470 118.475 116.040 1.00 14.01 ? 312  GLN C NE2 1 
ATOM   9782  N N   . GLU C 1 334 ? 148.315 122.315 114.658 1.00 17.38 ? 313  GLU C N   1 
ATOM   9783  C CA  . GLU C 1 334 ? 149.669 122.839 114.805 1.00 17.38 ? 313  GLU C CA  1 
ATOM   9784  C C   . GLU C 1 334 ? 150.672 122.035 113.988 1.00 17.38 ? 313  GLU C C   1 
ATOM   9785  O O   . GLU C 1 334 ? 151.631 122.593 113.444 1.00 17.38 ? 313  GLU C O   1 
ATOM   9786  C CB  . GLU C 1 334 ? 150.069 122.845 116.279 1.00 17.38 ? 313  GLU C CB  1 
ATOM   9787  C CG  . GLU C 1 334 ? 149.244 123.782 117.134 1.00 17.38 ? 313  GLU C CG  1 
ATOM   9788  C CD  . GLU C 1 334 ? 150.022 124.995 117.591 1.00 17.38 ? 313  GLU C CD  1 
ATOM   9789  O OE1 . GLU C 1 334 ? 149.562 125.675 118.533 1.00 17.38 ? 313  GLU C OE1 1 
ATOM   9790  O OE2 . GLU C 1 334 ? 151.092 125.267 117.009 1.00 17.38 ? 313  GLU C OE2 1 
ATOM   9791  N N   . SER C 1 335 ? 150.468 120.725 113.887 1.00 20.84 ? 314  SER C N   1 
ATOM   9792  C CA  . SER C 1 335 ? 151.383 119.860 113.155 1.00 20.84 ? 314  SER C CA  1 
ATOM   9793  C C   . SER C 1 335 ? 151.308 120.043 111.646 1.00 20.84 ? 314  SER C C   1 
ATOM   9794  O O   . SER C 1 335 ? 152.137 119.471 110.931 1.00 20.84 ? 314  SER C O   1 
ATOM   9795  C CB  . SER C 1 335 ? 151.107 118.396 113.498 1.00 20.84 ? 314  SER C CB  1 
ATOM   9796  O OG  . SER C 1 335 ? 151.966 117.539 112.767 1.00 20.84 ? 314  SER C OG  1 
ATOM   9797  N N   . ILE C 1 336 ? 150.337 120.806 111.141 1.00 17.12 ? 315  ILE C N   1 
ATOM   9798  C CA  . ILE C 1 336 ? 150.194 121.048 109.711 1.00 17.12 ? 315  ILE C CA  1 
ATOM   9799  C C   . ILE C 1 336 ? 150.054 122.522 109.376 1.00 17.12 ? 315  ILE C C   1 
ATOM   9800  O O   . ILE C 1 336 ? 149.865 122.863 108.208 1.00 17.12 ? 315  ILE C O   1 
ATOM   9801  C CB  . ILE C 1 336 ? 149.003 120.263 109.124 1.00 17.12 ? 315  ILE C CB  1 
ATOM   9802  C CG1 . ILE C 1 336 ? 147.684 120.857 109.617 1.00 17.12 ? 315  ILE C CG1 1 
ATOM   9803  C CG2 . ILE C 1 336 ? 149.102 118.796 109.474 1.00 17.12 ? 315  ILE C CG2 1 
ATOM   9804  C CD1 . ILE C 1 336 ? 146.527 120.632 108.681 1.00 17.12 ? 315  ILE C CD1 1 
ATOM   9805  N N   . TYR C 1 337 ? 150.148 123.412 110.365 1.00 17.38 ? 316  TYR C N   1 
ATOM   9806  C CA  . TYR C 1 337 ? 149.814 124.814 110.145 1.00 17.38 ? 316  TYR C CA  1 
ATOM   9807  C C   . TYR C 1 337 ? 150.715 125.453 109.096 1.00 17.38 ? 316  TYR C C   1 
ATOM   9808  O O   . TYR C 1 337 ? 150.240 126.212 108.246 1.00 17.38 ? 316  TYR C O   1 
ATOM   9809  C CB  . TYR C 1 337 ? 149.900 125.578 111.462 1.00 17.38 ? 316  TYR C CB  1 
ATOM   9810  C CG  . TYR C 1 337 ? 149.846 127.076 111.313 1.00 17.38 ? 316  TYR C CG  1 
ATOM   9811  C CD1 . TYR C 1 337 ? 148.634 127.742 111.264 1.00 17.38 ? 316  TYR C CD1 1 
ATOM   9812  C CD2 . TYR C 1 337 ? 151.009 127.829 111.233 1.00 17.38 ? 316  TYR C CD2 1 
ATOM   9813  C CE1 . TYR C 1 337 ? 148.580 129.113 111.138 1.00 17.38 ? 316  TYR C CE1 1 
ATOM   9814  C CE2 . TYR C 1 337 ? 150.963 129.198 111.100 1.00 17.38 ? 316  TYR C CE2 1 
ATOM   9815  C CZ  . TYR C 1 337 ? 149.745 129.835 111.053 1.00 17.38 ? 316  TYR C CZ  1 
ATOM   9816  O OH  . TYR C 1 337 ? 149.695 131.202 110.922 1.00 17.38 ? 316  TYR C OH  1 
ATOM   9817  N N   . ASP C 1 338 ? 152.016 125.167 109.140 1.00 19.62 ? 317  ASP C N   1 
ATOM   9818  C CA  . ASP C 1 338 ? 152.953 125.867 108.266 1.00 19.62 ? 317  ASP C CA  1 
ATOM   9819  C C   . ASP C 1 338 ? 152.655 125.598 106.794 1.00 19.62 ? 317  ASP C C   1 
ATOM   9820  O O   . ASP C 1 338 ? 152.476 126.534 106.007 1.00 19.62 ? 317  ASP C O   1 
ATOM   9821  C CB  . ASP C 1 338 ? 154.388 125.467 108.614 1.00 19.62 ? 317  ASP C CB  1 
ATOM   9822  C CG  . ASP C 1 338 ? 154.620 123.970 108.520 1.00 19.62 ? 317  ASP C CG  1 
ATOM   9823  O OD1 . ASP C 1 338 ? 154.304 123.250 109.491 1.00 19.62 ? 317  ASP C OD1 1 
ATOM   9824  O OD2 . ASP C 1 338 ? 155.118 123.513 107.470 1.00 19.62 ? 317  ASP C OD2 1 
ATOM   9825  N N   . LYS C 1 339 ? 152.570 124.323 106.409 1.00 18.39 ? 318  LYS C N   1 
ATOM   9826  C CA  . LYS C 1 339 ? 152.347 123.980 105.007 1.00 18.39 ? 318  LYS C CA  1 
ATOM   9827  C C   . LYS C 1 339 ? 150.946 124.372 104.558 1.00 18.39 ? 318  LYS C C   1 
ATOM   9828  O O   . LYS C 1 339 ? 150.754 124.876 103.438 1.00 18.39 ? 318  LYS C O   1 
ATOM   9829  C CB  . LYS C 1 339 ? 152.576 122.485 104.800 1.00 18.39 ? 318  LYS C CB  1 
ATOM   9830  C CG  . LYS C 1 339 ? 152.538 122.035 103.354 1.00 18.39 ? 318  LYS C CG  1 
ATOM   9831  C CD  . LYS C 1 339 ? 152.263 120.544 103.267 1.00 18.39 ? 318  LYS C CD  1 
ATOM   9832  C CE  . LYS C 1 339 ? 153.160 119.760 104.215 1.00 18.39 ? 318  LYS C CE  1 
ATOM   9833  N NZ  . LYS C 1 339 ? 152.752 118.333 104.327 1.00 18.39 ? 318  LYS C NZ  1 
ATOM   9834  N N   . PHE C 1 340 ? 149.956 124.148 105.422 1.00 15.09 ? 319  PHE C N   1 
ATOM   9835  C CA  . PHE C 1 340 ? 148.590 124.494 105.066 1.00 15.09 ? 319  PHE C CA  1 
ATOM   9836  C C   . PHE C 1 340 ? 148.451 125.988 104.833 1.00 15.09 ? 319  PHE C C   1 
ATOM   9837  O O   . PHE C 1 340 ? 147.792 126.408 103.882 1.00 15.09 ? 319  PHE C O   1 
ATOM   9838  C CB  . PHE C 1 340 ? 147.619 124.033 106.147 1.00 15.09 ? 319  PHE C CB  1 
ATOM   9839  C CG  . PHE C 1 340 ? 146.183 124.162 105.748 1.00 15.09 ? 319  PHE C CG  1 
ATOM   9840  C CD1 . PHE C 1 340 ? 145.586 123.208 104.948 1.00 15.09 ? 319  PHE C CD1 1 
ATOM   9841  C CD2 . PHE C 1 340 ? 145.439 125.253 106.148 1.00 15.09 ? 319  PHE C CD2 1 
ATOM   9842  C CE1 . PHE C 1 340 ? 144.271 123.331 104.574 1.00 15.09 ? 319  PHE C CE1 1 
ATOM   9843  C CE2 . PHE C 1 340 ? 144.122 125.381 105.780 1.00 15.09 ? 319  PHE C CE2 1 
ATOM   9844  C CZ  . PHE C 1 340 ? 143.538 124.421 104.988 1.00 15.09 ? 319  PHE C CZ  1 
ATOM   9845  N N   . MET C 1 341 ? 149.078 126.809 105.678 1.00 15.61 ? 320  MET C N   1 
ATOM   9846  C CA  . MET C 1 341 ? 149.008 128.250 105.480 1.00 15.61 ? 320  MET C CA  1 
ATOM   9847  C C   . MET C 1 341 ? 149.859 128.719 104.311 1.00 15.61 ? 320  MET C C   1 
ATOM   9848  O O   . MET C 1 341 ? 149.498 129.699 103.657 1.00 15.61 ? 320  MET C O   1 
ATOM   9849  C CB  . MET C 1 341 ? 149.412 128.984 106.753 1.00 15.61 ? 320  MET C CB  1 
ATOM   9850  C CG  . MET C 1 341 ? 148.300 129.032 107.762 1.00 15.61 ? 320  MET C CG  1 
ATOM   9851  S SD  . MET C 1 341 ? 146.752 129.567 107.016 1.00 15.61 ? 320  MET C SD  1 
ATOM   9852  C CE  . MET C 1 341 ? 147.151 131.252 106.580 1.00 15.61 ? 320  MET C CE  1 
ATOM   9853  N N   . GLU C 1 342 ? 150.969 128.041 104.021 1.00 18.34 ? 321  GLU C N   1 
ATOM   9854  C CA  . GLU C 1 342 ? 151.672 128.294 102.769 1.00 18.34 ? 321  GLU C CA  1 
ATOM   9855  C C   . GLU C 1 342 ? 150.707 128.212 101.594 1.00 18.34 ? 321  GLU C C   1 
ATOM   9856  O O   . GLU C 1 342 ? 150.469 129.200 100.884 1.00 18.34 ? 321  GLU C O   1 
ATOM   9857  C CB  . GLU C 1 342 ? 152.805 127.284 102.594 1.00 18.34 ? 321  GLU C CB  1 
ATOM   9858  C CG  . GLU C 1 342 ? 154.114 127.686 103.231 1.00 18.34 ? 321  GLU C CG  1 
ATOM   9859  C CD  . GLU C 1 342 ? 155.008 126.493 103.493 1.00 18.34 ? 321  GLU C CD  1 
ATOM   9860  O OE1 . GLU C 1 342 ? 154.704 125.398 102.975 1.00 18.34 ? 321  GLU C OE1 1 
ATOM   9861  O OE2 . GLU C 1 342 ? 156.010 126.647 104.219 1.00 18.34 ? 321  GLU C OE2 1 
ATOM   9862  N N   . ARG C 1 343 ? 150.103 127.034 101.409 1.00 17.87 ? 322  ARG C N   1 
ATOM   9863  C CA  . ARG C 1 343 ? 149.204 126.847 100.273 1.00 17.87 ? 322  ARG C CA  1 
ATOM   9864  C C   . ARG C 1 343 ? 147.962 127.727 100.373 1.00 17.87 ? 322  ARG C C   1 
ATOM   9865  O O   . ARG C 1 343 ? 147.452 128.194 99.349  1.00 17.87 ? 322  ARG C O   1 
ATOM   9866  C CB  . ARG C 1 343 ? 148.809 125.379 100.149 1.00 17.87 ? 322  ARG C CB  1 
ATOM   9867  C CG  . ARG C 1 343 ? 149.916 124.412 100.482 1.00 17.87 ? 322  ARG C CG  1 
ATOM   9868  C CD  . ARG C 1 343 ? 150.976 124.409 99.401  1.00 17.87 ? 322  ARG C CD  1 
ATOM   9869  N NE  . ARG C 1 343 ? 150.399 124.142 98.091  1.00 17.87 ? 322  ARG C NE  1 
ATOM   9870  C CZ  . ARG C 1 343 ? 150.171 122.924 97.612  1.00 17.87 ? 322  ARG C CZ  1 
ATOM   9871  N NH1 . ARG C 1 343 ? 150.476 121.858 98.337  1.00 17.87 ? 322  ARG C NH1 1 
ATOM   9872  N NH2 . ARG C 1 343 ? 149.640 122.775 96.408  1.00 17.87 ? 322  ARG C NH2 1 
ATOM   9873  N N   . ALA C 1 344 ? 147.480 127.993 101.586 1.00 15.85 ? 323  ALA C N   1 
ATOM   9874  C CA  . ALA C 1 344 ? 146.278 128.800 101.751 1.00 15.85 ? 323  ALA C CA  1 
ATOM   9875  C C   . ALA C 1 344 ? 146.519 130.251 101.357 1.00 15.85 ? 323  ALA C C   1 
ATOM   9876  O O   . ALA C 1 344 ? 145.655 130.882 100.739 1.00 15.85 ? 323  ALA C O   1 
ATOM   9877  C CB  . ALA C 1 344 ? 145.791 128.710 103.194 1.00 15.85 ? 323  ALA C CB  1 
ATOM   9878  N N   . VAL C 1 345 ? 147.673 130.806 101.720 1.00 16.71 ? 324  VAL C N   1 
ATOM   9879  C CA  . VAL C 1 345 ? 147.992 132.163 101.300 1.00 16.71 ? 324  VAL C CA  1 
ATOM   9880  C C   . VAL C 1 345 ? 148.244 132.207 99.800  1.00 16.71 ? 324  VAL C C   1 
ATOM   9881  O O   . VAL C 1 345 ? 147.843 133.160 99.123  1.00 16.71 ? 324  VAL C O   1 
ATOM   9882  C CB  . VAL C 1 345 ? 149.184 132.705 102.107 1.00 16.71 ? 324  VAL C CB  1 
ATOM   9883  C CG1 . VAL C 1 345 ? 149.690 134.003 101.511 1.00 16.71 ? 324  VAL C CG1 1 
ATOM   9884  C CG2 . VAL C 1 345 ? 148.771 132.917 103.547 1.00 16.71 ? 324  VAL C CG2 1 
ATOM   9885  N N   . GLN C 1 346 ? 148.897 131.180 99.244  1.00 19.36 ? 325  GLN C N   1 
ATOM   9886  C CA  . GLN C 1 346 ? 149.011 131.138 97.788  1.00 19.36 ? 325  GLN C CA  1 
ATOM   9887  C C   . GLN C 1 346 ? 147.646 131.071 97.117  1.00 19.36 ? 325  GLN C C   1 
ATOM   9888  O O   . GLN C 1 346 ? 147.497 131.515 95.973  1.00 19.36 ? 325  GLN C O   1 
ATOM   9889  C CB  . GLN C 1 346 ? 149.872 129.962 97.332  1.00 19.36 ? 325  GLN C CB  1 
ATOM   9890  C CG  . GLN C 1 346 ? 151.176 129.805 98.071  1.00 19.36 ? 325  GLN C CG  1 
ATOM   9891  C CD  . GLN C 1 346 ? 152.281 129.271 97.185  1.00 19.36 ? 325  GLN C CD  1 
ATOM   9892  O OE1 . GLN C 1 346 ? 152.027 128.523 96.243  1.00 19.36 ? 325  GLN C OE1 1 
ATOM   9893  N NE2 . GLN C 1 346 ? 153.516 129.652 97.485  1.00 19.36 ? 325  GLN C NE2 1 
ATOM   9894  N N   . ARG C 1 347 ? 146.644 130.521 97.803  1.00 16.94 ? 326  ARG C N   1 
ATOM   9895  C CA  . ARG C 1 347 ? 145.322 130.378 97.205  1.00 16.94 ? 326  ARG C CA  1 
ATOM   9896  C C   . ARG C 1 347 ? 144.463 131.630 97.336  1.00 16.94 ? 326  ARG C C   1 
ATOM   9897  O O   . ARG C 1 347 ? 143.769 131.994 96.383  1.00 16.94 ? 326  ARG C O   1 
ATOM   9898  C CB  . ARG C 1 347 ? 144.588 129.186 97.822  1.00 16.94 ? 326  ARG C CB  1 
ATOM   9899  C CG  . ARG C 1 347 ? 144.906 127.864 97.148  1.00 16.94 ? 326  ARG C CG  1 
ATOM   9900  C CD  . ARG C 1 347 ? 144.562 127.909 95.666  1.00 16.94 ? 326  ARG C CD  1 
ATOM   9901  N NE  . ARG C 1 347 ? 144.607 126.592 95.037  1.00 16.94 ? 326  ARG C NE  1 
ATOM   9902  C CZ  . ARG C 1 347 ? 143.720 125.624 95.253  1.00 16.94 ? 326  ARG C CZ  1 
ATOM   9903  N NH1 . ARG C 1 347 ? 142.702 125.820 96.079  1.00 16.94 ? 326  ARG C NH1 1 
ATOM   9904  N NH2 . ARG C 1 347 ? 143.849 124.459 94.634  1.00 16.94 ? 326  ARG C NH2 1 
ATOM   9905  N N   . VAL C 1 348 ? 144.485 132.298 98.491  1.00 16.15 ? 327  VAL C N   1 
ATOM   9906  C CA  . VAL C 1 348 ? 143.616 133.458 98.683  1.00 16.15 ? 327  VAL C CA  1 
ATOM   9907  C C   . VAL C 1 348 ? 144.061 134.616 97.800  1.00 16.15 ? 327  VAL C C   1 
ATOM   9908  O O   . VAL C 1 348 ? 143.231 135.327 97.221  1.00 16.15 ? 327  VAL C O   1 
ATOM   9909  C CB  . VAL C 1 348 ? 143.567 133.861 100.167 1.00 16.15 ? 327  VAL C CB  1 
ATOM   9910  C CG1 . VAL C 1 348 ? 143.084 135.285 100.310 1.00 16.15 ? 327  VAL C CG1 1 
ATOM   9911  C CG2 . VAL C 1 348 ? 142.656 132.930 100.926 1.00 16.15 ? 327  VAL C CG2 1 
ATOM   9912  N N   . GLN C 1 349 ? 145.371 134.822 97.671  1.00 17.99 ? 328  GLN C N   1 
ATOM   9913  C CA  . GLN C 1 349 ? 145.878 135.835 96.756  1.00 17.99 ? 328  GLN C CA  1 
ATOM   9914  C C   . GLN C 1 349 ? 145.717 135.441 95.294  1.00 17.99 ? 328  GLN C C   1 
ATOM   9915  O O   . GLN C 1 349 ? 145.958 136.276 94.417  1.00 17.99 ? 328  GLN C O   1 
ATOM   9916  C CB  . GLN C 1 349 ? 147.348 136.130 97.054  1.00 17.99 ? 328  GLN C CB  1 
ATOM   9917  C CG  . GLN C 1 349 ? 147.658 136.299 98.530  1.00 17.99 ? 328  GLN C CG  1 
ATOM   9918  C CD  . GLN C 1 349 ? 149.143 136.241 98.818  1.00 17.99 ? 328  GLN C CD  1 
ATOM   9919  O OE1 . GLN C 1 349 ? 149.867 135.438 98.230  1.00 17.99 ? 328  GLN C OE1 1 
ATOM   9920  N NE2 . GLN C 1 349 ? 149.606 137.091 99.725  1.00 17.99 ? 328  GLN C NE2 1 
ATOM   9921  N N   . ALA C 1 350 ? 145.328 134.200 95.011  1.00 16.91 ? 329  ALA C N   1 
ATOM   9922  C CA  . ALA C 1 350 ? 145.013 133.771 93.656  1.00 16.91 ? 329  ALA C CA  1 
ATOM   9923  C C   . ALA C 1 350 ? 143.556 134.017 93.291  1.00 16.91 ? 329  ALA C C   1 
ATOM   9924  O O   . ALA C 1 350 ? 143.136 133.653 92.189  1.00 16.91 ? 329  ALA C O   1 
ATOM   9925  C CB  . ALA C 1 350 ? 145.346 132.289 93.475  1.00 16.91 ? 329  ALA C CB  1 
ATOM   9926  N N   . ILE C 1 351 ? 142.782 134.612 94.191  1.00 17.55 ? 330  ILE C N   1 
ATOM   9927  C CA  . ILE C 1 351 ? 141.408 134.996 93.897  1.00 17.55 ? 330  ILE C CA  1 
ATOM   9928  C C   . ILE C 1 351 ? 141.426 136.235 93.012  1.00 17.55 ? 330  ILE C C   1 
ATOM   9929  O O   . ILE C 1 351 ? 142.145 137.202 93.289  1.00 17.55 ? 330  ILE C O   1 
ATOM   9930  C CB  . ILE C 1 351 ? 140.630 135.244 95.198  1.00 17.55 ? 330  ILE C CB  1 
ATOM   9931  C CG1 . ILE C 1 351 ? 140.435 133.929 95.949  1.00 17.55 ? 330  ILE C CG1 1 
ATOM   9932  C CG2 . ILE C 1 351 ? 139.297 135.896 94.914  1.00 17.55 ? 330  ILE C CG2 1 
ATOM   9933  C CD1 . ILE C 1 351 ? 140.121 134.104 97.406  1.00 17.55 ? 330  ILE C CD1 1 
ATOM   9934  N N   . LYS C 1 352 ? 140.644 136.204 91.934  1.00 23.15 ? 331  LYS C N   1 
ATOM   9935  C CA  . LYS C 1 352 ? 140.600 137.297 90.965  1.00 23.15 ? 331  LYS C CA  1 
ATOM   9936  C C   . LYS C 1 352 ? 139.443 138.220 91.323  1.00 23.15 ? 331  LYS C C   1 
ATOM   9937  O O   . LYS C 1 352 ? 138.288 137.940 90.998  1.00 23.15 ? 331  LYS C O   1 
ATOM   9938  C CB  . LYS C 1 352 ? 140.459 136.756 89.547  1.00 23.15 ? 331  LYS C CB  1 
ATOM   9939  C CG  . LYS C 1 352 ? 140.461 137.833 88.471  1.00 23.15 ? 331  LYS C CG  1 
ATOM   9940  C CD  . LYS C 1 352 ? 139.058 138.113 87.957  1.00 23.15 ? 331  LYS C CD  1 
ATOM   9941  C CE  . LYS C 1 352 ? 139.034 139.279 86.986  1.00 23.15 ? 331  LYS C CE  1 
ATOM   9942  N NZ  . LYS C 1 352 ? 137.658 139.562 86.497  1.00 23.15 ? 331  LYS C NZ  1 
ATOM   9943  N N   . GLN C 1 353 ? 139.750 139.320 92.004  1.00 25.96 ? 332  GLN C N   1 
ATOM   9944  C CA  . GLN C 1 353 ? 138.759 140.356 92.254  1.00 25.96 ? 332  GLN C CA  1 
ATOM   9945  C C   . GLN C 1 353 ? 138.646 141.265 91.037  1.00 25.96 ? 332  GLN C C   1 
ATOM   9946  O O   . GLN C 1 353 ? 139.622 141.502 90.322  1.00 25.96 ? 332  GLN C O   1 
ATOM   9947  C CB  . GLN C 1 353 ? 139.129 141.172 93.495  1.00 25.96 ? 332  GLN C CB  1 
ATOM   9948  C CG  . GLN C 1 353 ? 138.023 142.088 93.994  1.00 25.96 ? 332  GLN C CG  1 
ATOM   9949  C CD  . GLN C 1 353 ? 137.884 142.070 95.506  1.00 25.96 ? 332  GLN C CD  1 
ATOM   9950  O OE1 . GLN C 1 353 ? 138.876 142.000 96.229  1.00 25.96 ? 332  GLN C OE1 1 
ATOM   9951  N NE2 . GLN C 1 353 ? 136.650 142.131 95.991  1.00 25.96 ? 332  GLN C NE2 1 
ATOM   9952  N N   . GLY C 1 354 ? 137.438 141.764 90.796  1.00 23.24 ? 333  GLY C N   1 
ATOM   9953  C CA  . GLY C 1 354 ? 137.211 142.597 89.630  1.00 23.24 ? 333  GLY C CA  1 
ATOM   9954  C C   . GLY C 1 354 ? 135.736 142.892 89.459  1.00 23.24 ? 333  GLY C C   1 
ATOM   9955  O O   . GLY C 1 354 ? 134.972 142.881 90.424  1.00 23.24 ? 333  GLY C O   1 
ATOM   9956  N N   . ASP C 1 355 ? 135.352 143.156 88.218  1.00 23.16 ? 334  ASP C N   1 
ATOM   9957  C CA  . ASP C 1 355 ? 133.958 143.446 87.918  1.00 23.16 ? 334  ASP C CA  1 
ATOM   9958  C C   . ASP C 1 355 ? 133.138 142.179 88.094  1.00 23.16 ? 334  ASP C C   1 
ATOM   9959  O O   . ASP C 1 355 ? 133.402 141.184 87.408  1.00 23.16 ? 334  ASP C O   1 
ATOM   9960  C CB  . ASP C 1 355 ? 133.812 143.978 86.499  1.00 23.16 ? 334  ASP C CB  1 
ATOM   9961  C CG  . ASP C 1 355 ? 132.380 144.329 86.154  1.00 23.16 ? 334  ASP C CG  1 
ATOM   9962  O OD1 . ASP C 1 355 ? 131.658 144.822 87.044  1.00 23.16 ? 334  ASP C OD1 1 
ATOM   9963  O OD2 . ASP C 1 355 ? 131.974 144.114 84.994  1.00 23.16 ? 334  ASP C OD2 1 
ATOM   9964  N N   . PRO C 1 356 ? 132.137 142.168 88.978  1.00 18.77 ? 335  PRO C N   1 
ATOM   9965  C CA  . PRO C 1 356 ? 131.419 140.914 89.250  1.00 18.77 ? 335  PRO C CA  1 
ATOM   9966  C C   . PRO C 1 356 ? 130.781 140.302 88.019  1.00 18.77 ? 335  PRO C C   1 
ATOM   9967  O O   . PRO C 1 356 ? 130.695 139.073 87.912  1.00 18.77 ? 335  PRO C O   1 
ATOM   9968  C CB  . PRO C 1 356 ? 130.365 141.337 90.282  1.00 18.77 ? 335  PRO C CB  1 
ATOM   9969  C CG  . PRO C 1 356 ? 130.883 142.587 90.876  1.00 18.77 ? 335  PRO C CG  1 
ATOM   9970  C CD  . PRO C 1 356 ? 131.649 143.279 89.807  1.00 18.77 ? 335  PRO C CD  1 
ATOM   9971  N N   . ARG C 1 357 ? 130.326 141.123 87.086  1.00 23.04 ? 336  ARG C N   1 
ATOM   9972  C CA  . ARG C 1 357 ? 129.546 140.642 85.949  1.00 23.04 ? 336  ARG C CA  1 
ATOM   9973  C C   . ARG C 1 357 ? 130.396 140.471 84.697  1.00 23.04 ? 336  ARG C C   1 
ATOM   9974  O O   . ARG C 1 357 ? 130.072 141.052 83.663  1.00 23.04 ? 336  ARG C O   1 
ATOM   9975  C CB  . ARG C 1 357 ? 128.391 141.599 85.685  1.00 23.04 ? 336  ARG C CB  1 
ATOM   9976  C CG  . ARG C 1 357 ? 128.743 143.050 85.945  1.00 23.04 ? 336  ARG C CG  1 
ATOM   9977  C CD  . ARG C 1 357 ? 127.598 143.983 85.592  1.00 23.04 ? 336  ARG C CD  1 
ATOM   9978  N NE  . ARG C 1 357 ? 127.887 145.382 85.905  1.00 23.04 ? 336  ARG C NE  1 
ATOM   9979  C CZ  . ARG C 1 357 ? 128.800 146.124 85.284  1.00 23.04 ? 336  ARG C CZ  1 
ATOM   9980  N NH1 . ARG C 1 357 ? 129.528 145.614 84.298  1.00 23.04 ? 336  ARG C NH1 1 
ATOM   9981  N NH2 . ARG C 1 357 ? 128.982 147.386 85.644  1.00 23.04 ? 336  ARG C NH2 1 
ATOM   9982  N N   . GLU C 1 358 ? 131.479 139.691 84.725  1.00 28.22 ? 337  GLU C N   1 
ATOM   9983  C CA  . GLU C 1 358 ? 132.172 139.520 83.453  1.00 28.22 ? 337  GLU C CA  1 
ATOM   9984  C C   . GLU C 1 358 ? 132.128 138.090 82.932  1.00 28.22 ? 337  GLU C C   1 
ATOM   9985  O O   . GLU C 1 358 ? 131.369 137.796 82.003  1.00 28.22 ? 337  GLU C O   1 
ATOM   9986  C CB  . GLU C 1 358 ? 133.630 139.962 83.607  1.00 28.22 ? 337  GLU C CB  1 
ATOM   9987  C CG  . GLU C 1 358 ? 134.431 140.005 82.320  1.00 28.22 ? 337  GLU C CG  1 
ATOM   9988  C CD  . GLU C 1 358 ? 134.033 141.154 81.418  1.00 28.22 ? 337  GLU C CD  1 
ATOM   9989  O OE1 . GLU C 1 358 ? 133.241 142.015 81.856  1.00 28.22 ? 337  GLU C OE1 1 
ATOM   9990  O OE2 . GLU C 1 358 ? 134.523 141.203 80.270  1.00 28.22 ? 337  GLU C OE2 1 
ATOM   9991  N N   . SER C 1 359 ? 132.918 137.187 83.512  1.00 27.73 ? 338  SER C N   1 
ATOM   9992  C CA  . SER C 1 359 ? 132.668 135.758 83.378  1.00 27.73 ? 338  SER C CA  1 
ATOM   9993  C C   . SER C 1 359 ? 133.172 134.998 84.596  1.00 27.73 ? 338  SER C C   1 
ATOM   9994  O O   . SER C 1 359 ? 132.655 133.932 84.941  1.00 27.73 ? 338  SER C O   1 
ATOM   9995  C CB  . SER C 1 359 ? 133.322 135.212 82.110  1.00 27.73 ? 338  SER C CB  1 
ATOM   9996  O OG  . SER C 1 359 ? 133.273 133.796 82.089  1.00 27.73 ? 338  SER C OG  1 
ATOM   9997  N N   . ASP C 1 360 ? 134.188 135.560 85.250  1.00 29.28 ? 339  ASP C N   1 
ATOM   9998  C CA  . ASP C 1 360 ? 135.079 134.780 86.097  1.00 29.28 ? 339  ASP C CA  1 
ATOM   9999  C C   . ASP C 1 360 ? 135.560 135.505 87.343  1.00 29.28 ? 339  ASP C C   1 
ATOM   10000 O O   . ASP C 1 360 ? 136.421 134.971 88.046  1.00 29.28 ? 339  ASP C O   1 
ATOM   10001 C CB  . ASP C 1 360 ? 136.297 134.320 85.281  1.00 29.28 ? 339  ASP C CB  1 
ATOM   10002 C CG  . ASP C 1 360 ? 137.128 135.482 84.771  1.00 29.28 ? 339  ASP C CG  1 
ATOM   10003 O OD1 . ASP C 1 360 ? 136.746 136.646 85.009  1.00 29.28 ? 339  ASP C OD1 1 
ATOM   10004 O OD2 . ASP C 1 360 ? 138.166 135.233 84.122  1.00 29.28 ? 339  ASP C OD2 1 
ATOM   10005 N N   . THR C 1 361 ? 135.066 136.704 87.619  1.00 24.47 ? 340  THR C N   1 
ATOM   10006 C CA  . THR C 1 361 ? 135.407 137.399 88.848  1.00 24.47 ? 340  THR C CA  1 
ATOM   10007 C C   . THR C 1 361 ? 134.991 136.562 90.048  1.00 24.47 ? 340  THR C C   1 
ATOM   10008 O O   . THR C 1 361 ? 133.805 136.278 90.228  1.00 24.47 ? 340  THR C O   1 
ATOM   10009 C CB  . THR C 1 361 ? 134.727 138.761 88.880  1.00 24.47 ? 340  THR C CB  1 
ATOM   10010 O OG1 . THR C 1 361 ? 135.175 139.539 87.765  1.00 24.47 ? 340  THR C OG1 1 
ATOM   10011 C CG2 . THR C 1 361 ? 135.060 139.481 90.156  1.00 24.47 ? 340  THR C CG2 1 
ATOM   10012 N N   . MET C 1 362 ? 135.955 136.146 90.867  1.00 23.76 ? 341  MET C N   1 
ATOM   10013 C CA  . MET C 1 362 ? 135.628 135.281 91.991  1.00 23.76 ? 341  MET C CA  1 
ATOM   10014 C C   . MET C 1 362 ? 134.991 136.026 93.153  1.00 23.76 ? 341  MET C C   1 
ATOM   10015 O O   . MET C 1 362 ? 134.403 135.384 94.028  1.00 23.76 ? 341  MET C O   1 
ATOM   10016 C CB  . MET C 1 362 ? 136.874 134.533 92.466  1.00 23.76 ? 341  MET C CB  1 
ATOM   10017 C CG  . MET C 1 362 ? 137.086 133.210 91.753  1.00 23.76 ? 341  MET C CG  1 
ATOM   10018 S SD  . MET C 1 362 ? 137.961 133.244 90.185  1.00 23.76 ? 341  MET C SD  1 
ATOM   10019 C CE  . MET C 1 362 ? 139.649 133.403 90.742  1.00 23.76 ? 341  MET C CE  1 
ATOM   10020 N N   . ILE C 1 363 ? 135.075 137.352 93.190  1.00 19.96 ? 342  ILE C N   1 
ATOM   10021 C CA  . ILE C 1 363 ? 134.563 138.114 94.323  1.00 19.96 ? 342  ILE C CA  1 
ATOM   10022 C C   . ILE C 1 363 ? 134.201 139.520 93.856  1.00 19.96 ? 342  ILE C C   1 
ATOM   10023 O O   . ILE C 1 363 ? 134.976 140.161 93.140  1.00 19.96 ? 342  ILE C O   1 
ATOM   10024 C CB  . ILE C 1 363 ? 135.586 138.135 95.478  1.00 19.96 ? 342  ILE C CB  1 
ATOM   10025 C CG1 . ILE C 1 363 ? 135.052 138.908 96.675  1.00 19.96 ? 342  ILE C CG1 1 
ATOM   10026 C CG2 . ILE C 1 363 ? 136.914 138.694 95.022  1.00 19.96 ? 342  ILE C CG2 1 
ATOM   10027 C CD1 . ILE C 1 363 ? 135.894 138.749 97.904  1.00 19.96 ? 342  ILE C CD1 1 
ATOM   10028 N N   . GLY C 1 364 ? 133.024 139.998 94.259  1.00 17.47 ? 343  GLY C N   1 
ATOM   10029 C CA  . GLY C 1 364 ? 132.513 141.269 93.780  1.00 17.47 ? 343  GLY C CA  1 
ATOM   10030 C C   . GLY C 1 364 ? 132.167 142.277 94.857  1.00 17.47 ? 343  GLY C C   1 
ATOM   10031 O O   . GLY C 1 364 ? 132.575 142.124 96.009  1.00 17.47 ? 343  GLY C O   1 
ATOM   10032 N N   . ALA C 1 365 ? 131.421 143.317 94.489  1.00 16.56 ? 344  ALA C N   1 
ATOM   10033 C CA  . ALA C 1 365 ? 131.089 144.392 95.413  1.00 16.56 ? 344  ALA C CA  1 
ATOM   10034 C C   . ALA C 1 365 ? 130.199 143.878 96.540  1.00 16.56 ? 344  ALA C C   1 
ATOM   10035 O O   . ALA C 1 365 ? 129.492 142.879 96.398  1.00 16.56 ? 344  ALA C O   1 
ATOM   10036 C CB  . ALA C 1 365 ? 130.396 145.534 94.678  1.00 16.56 ? 344  ALA C CB  1 
ATOM   10037 N N   . GLN C 1 366 ? 130.233 144.572 97.677  1.00 18.22 ? 345  GLN C N   1 
ATOM   10038 C CA  . GLN C 1 366 ? 129.725 143.902 98.862  1.00 18.22 ? 345  GLN C CA  1 
ATOM   10039 C C   . GLN C 1 366 ? 128.207 143.962 98.970  1.00 18.22 ? 345  GLN C C   1 
ATOM   10040 O O   . GLN C 1 366 ? 127.527 142.998 98.607  1.00 18.22 ? 345  GLN C O   1 
ATOM   10041 C CB  . GLN C 1 366 ? 130.338 144.534 100.113 1.00 18.22 ? 345  GLN C CB  1 
ATOM   10042 C CG  . GLN C 1 366 ? 131.829 144.326 100.298 1.00 18.22 ? 345  GLN C CG  1 
ATOM   10043 C CD  . GLN C 1 366 ? 132.245 142.878 100.250 1.00 18.22 ? 345  GLN C CD  1 
ATOM   10044 O OE1 . GLN C 1 366 ? 131.910 142.098 101.140 1.00 18.22 ? 345  GLN C OE1 1 
ATOM   10045 N NE2 . GLN C 1 366 ? 132.994 142.511 99.215  1.00 18.22 ? 345  GLN C NE2 1 
ATOM   10046 N N   . ALA C 1 367 ? 127.657 145.082 99.443  1.00 19.49 ? 346  ALA C N   1 
ATOM   10047 C CA  . ALA C 1 367 ? 126.218 145.301 99.357  1.00 19.49 ? 346  ALA C CA  1 
ATOM   10048 C C   . ALA C 1 367 ? 125.847 146.773 99.228  1.00 19.49 ? 346  ALA C C   1 
ATOM   10049 O O   . ALA C 1 367 ? 124.812 147.109 98.645  1.00 19.49 ? 346  ALA C O   1 
ATOM   10050 C CB  . ALA C 1 367 ? 125.520 144.698 100.578 1.00 19.49 ? 346  ALA C CB  1 
ATOM   10051 N N   . SER C 1 368 ? 126.683 147.654 99.783  1.00 19.28 ? 347  SER C N   1 
ATOM   10052 C CA  . SER C 1 368 ? 126.289 149.041 100.013 1.00 19.28 ? 347  SER C CA  1 
ATOM   10053 C C   . SER C 1 368 ? 127.435 149.863 100.587 1.00 19.28 ? 347  SER C C   1 
ATOM   10054 O O   . SER C 1 368 ? 128.573 149.391 100.656 1.00 19.28 ? 347  SER C O   1 
ATOM   10055 C CB  . SER C 1 368 ? 125.085 149.110 100.957 1.00 19.28 ? 347  SER C CB  1 
ATOM   10056 O OG  . SER C 1 368 ? 125.271 148.290 102.095 1.00 19.28 ? 347  SER C OG  1 
ATOM   10057 N N   . SER C 1 369 ? 127.141 151.104 100.985 1.00 21.24 ? 348  SER C N   1 
ATOM   10058 C CA  . SER C 1 369 ? 128.117 151.896 101.728 1.00 21.24 ? 348  SER C CA  1 
ATOM   10059 C C   . SER C 1 369 ? 128.225 151.429 103.174 1.00 21.24 ? 348  SER C C   1 
ATOM   10060 O O   . SER C 1 369 ? 129.327 151.373 103.736 1.00 21.24 ? 348  SER C O   1 
ATOM   10061 C CB  . SER C 1 369 ? 127.741 153.375 101.682 1.00 21.24 ? 348  SER C CB  1 
ATOM   10062 O OG  . SER C 1 369 ? 127.498 153.809 100.359 1.00 21.24 ? 348  SER C OG  1 
ATOM   10063 N N   . GLU C 1 370 ? 127.087 151.106 103.798 1.00 23.42 ? 349  GLU C N   1 
ATOM   10064 C CA  . GLU C 1 370 ? 127.101 150.654 105.185 1.00 23.42 ? 349  GLU C CA  1 
ATOM   10065 C C   . GLU C 1 370 ? 127.871 149.350 105.334 1.00 23.42 ? 349  GLU C C   1 
ATOM   10066 O O   . GLU C 1 370 ? 128.552 149.134 106.347 1.00 23.42 ? 349  GLU C O   1 
ATOM   10067 C CB  . GLU C 1 370 ? 125.672 150.488 105.695 1.00 23.42 ? 349  GLU C CB  1 
ATOM   10068 C CG  . GLU C 1 370 ? 125.557 150.491 107.203 1.00 23.42 ? 349  GLU C CG  1 
ATOM   10069 C CD  . GLU C 1 370 ? 124.145 150.749 107.684 1.00 23.42 ? 349  GLU C CD  1 
ATOM   10070 O OE1 . GLU C 1 370 ? 123.195 150.439 106.935 1.00 23.42 ? 349  GLU C OE1 1 
ATOM   10071 O OE2 . GLU C 1 370 ? 123.986 151.254 108.815 1.00 23.42 ? 349  GLU C OE2 1 
ATOM   10072 N N   . GLN C 1 371 ? 127.788 148.481 104.328 1.00 22.05 ? 350  GLN C N   1 
ATOM   10073 C CA  . GLN C 1 371 ? 128.585 147.263 104.333 1.00 22.05 ? 350  GLN C CA  1 
ATOM   10074 C C   . GLN C 1 371 ? 130.067 147.587 104.413 1.00 22.05 ? 350  GLN C C   1 
ATOM   10075 O O   . GLN C 1 371 ? 130.789 147.039 105.253 1.00 22.05 ? 350  GLN C O   1 
ATOM   10076 C CB  . GLN C 1 371 ? 128.273 146.436 103.087 1.00 22.05 ? 350  GLN C CB  1 
ATOM   10077 C CG  . GLN C 1 371 ? 128.809 145.019 103.133 1.00 22.05 ? 350  GLN C CG  1 
ATOM   10078 C CD  . GLN C 1 371 ? 128.003 144.107 104.028 1.00 22.05 ? 350  GLN C CD  1 
ATOM   10079 O OE1 . GLN C 1 371 ? 126.905 144.449 104.459 1.00 22.05 ? 350  GLN C OE1 1 
ATOM   10080 N NE2 . GLN C 1 371 ? 128.551 142.936 104.318 1.00 22.05 ? 350  GLN C NE2 1 
ATOM   10081 N N   . LYS C 1 372 ? 130.540 148.491 103.553 1.00 20.73 ? 351  LYS C N   1 
ATOM   10082 C CA  . LYS C 1 372 ? 131.952 148.847 103.588 1.00 20.73 ? 351  LYS C CA  1 
ATOM   10083 C C   . LYS C 1 372 ? 132.341 149.515 104.895 1.00 20.73 ? 351  LYS C C   1 
ATOM   10084 O O   . LYS C 1 372 ? 133.432 149.256 105.407 1.00 20.73 ? 351  LYS C O   1 
ATOM   10085 C CB  . LYS C 1 372 ? 132.320 149.748 102.414 1.00 20.73 ? 351  LYS C CB  1 
ATOM   10086 C CG  . LYS C 1 372 ? 133.034 149.019 101.294 1.00 20.73 ? 351  LYS C CG  1 
ATOM   10087 C CD  . LYS C 1 372 ? 133.590 149.993 100.279 1.00 20.73 ? 351  LYS C CD  1 
ATOM   10088 C CE  . LYS C 1 372 ? 134.957 150.486 100.672 1.00 20.73 ? 351  LYS C CE  1 
ATOM   10089 N NZ  . LYS C 1 372 ? 135.544 151.310 99.584  1.00 20.73 ? 351  LYS C NZ  1 
ATOM   10090 N N   . GLU C 1 373 ? 131.492 150.381 105.454 1.00 23.03 ? 352  GLU C N   1 
ATOM   10091 C CA  . GLU C 1 373 ? 131.890 151.036 106.698 1.00 23.03 ? 352  GLU C CA  1 
ATOM   10092 C C   . GLU C 1 373 ? 132.023 150.014 107.825 1.00 23.03 ? 352  GLU C C   1 
ATOM   10093 O O   . GLU C 1 373 ? 132.997 150.039 108.584 1.00 23.03 ? 352  GLU C O   1 
ATOM   10094 C CB  . GLU C 1 373 ? 130.939 152.184 107.074 1.00 23.03 ? 352  GLU C CB  1 
ATOM   10095 C CG  . GLU C 1 373 ? 129.485 151.872 107.347 1.00 23.03 ? 352  GLU C CG  1 
ATOM   10096 C CD  . GLU C 1 373 ? 129.227 151.457 108.786 1.00 23.03 ? 352  GLU C CD  1 
ATOM   10097 O OE1 . GLU C 1 373 ? 130.074 151.760 109.650 1.00 23.03 ? 352  GLU C OE1 1 
ATOM   10098 O OE2 . GLU C 1 373 ? 128.169 150.858 109.061 1.00 23.03 ? 352  GLU C OE2 1 
ATOM   10099 N N   . LYS C 1 374 ? 131.073 149.073 107.925 1.00 22.23 ? 353  LYS C N   1 
ATOM   10100 C CA  . LYS C 1 374 ? 131.191 148.037 108.951 1.00 22.23 ? 353  LYS C CA  1 
ATOM   10101 C C   . LYS C 1 374 ? 132.419 147.161 108.731 1.00 22.23 ? 353  LYS C C   1 
ATOM   10102 O O   . LYS C 1 374 ? 133.162 146.873 109.681 1.00 22.23 ? 353  LYS C O   1 
ATOM   10103 C CB  . LYS C 1 374 ? 129.941 147.160 108.988 1.00 22.23 ? 353  LYS C CB  1 
ATOM   10104 C CG  . LYS C 1 374 ? 128.689 147.834 109.496 1.00 22.23 ? 353  LYS C CG  1 
ATOM   10105 C CD  . LYS C 1 374 ? 127.660 146.787 109.895 1.00 22.23 ? 353  LYS C CD  1 
ATOM   10106 C CE  . LYS C 1 374 ? 126.251 147.345 109.879 1.00 22.23 ? 353  LYS C CE  1 
ATOM   10107 N NZ  . LYS C 1 374 ? 125.790 147.596 108.495 1.00 22.23 ? 353  LYS C NZ  1 
ATOM   10108 N N   . ILE C 1 375 ? 132.644 146.712 107.492 1.00 21.14 ? 354  ILE C N   1 
ATOM   10109 C CA  . ILE C 1 375 ? 133.771 145.820 107.230 1.00 21.14 ? 354  ILE C CA  1 
ATOM   10110 C C   . ILE C 1 375 ? 135.085 146.525 107.523 1.00 21.14 ? 354  ILE C C   1 
ATOM   10111 O O   . ILE C 1 375 ? 135.984 145.953 108.147 1.00 21.14 ? 354  ILE C O   1 
ATOM   10112 C CB  . ILE C 1 375 ? 133.729 145.286 105.786 1.00 21.14 ? 354  ILE C CB  1 
ATOM   10113 C CG1 . ILE C 1 375 ? 132.457 144.484 105.540 1.00 21.14 ? 354  ILE C CG1 1 
ATOM   10114 C CG2 . ILE C 1 375 ? 134.930 144.408 105.505 1.00 21.14 ? 354  ILE C CG2 1 
ATOM   10115 C CD1 . ILE C 1 375 ? 132.305 144.046 104.109 1.00 21.14 ? 354  ILE C CD1 1 
ATOM   10116 N N   . LEU C 1 376 ? 135.213 147.782 107.095 1.00 21.95 ? 355  LEU C N   1 
ATOM   10117 C CA  . LEU C 1 376 ? 136.443 148.529 107.326 1.00 21.95 ? 355  LEU C CA  1 
ATOM   10118 C C   . LEU C 1 376 ? 136.654 148.812 108.807 1.00 21.95 ? 355  LEU C C   1 
ATOM   10119 O O   . LEU C 1 376 ? 137.787 148.752 109.297 1.00 21.95 ? 355  LEU C O   1 
ATOM   10120 C CB  . LEU C 1 376 ? 136.415 149.825 106.520 1.00 21.95 ? 355  LEU C CB  1 
ATOM   10121 C CG  . LEU C 1 376 ? 136.738 149.656 105.034 1.00 21.95 ? 355  LEU C CG  1 
ATOM   10122 C CD1 . LEU C 1 376 ? 136.986 151.001 104.379 1.00 21.95 ? 355  LEU C CD1 1 
ATOM   10123 C CD2 . LEU C 1 376 ? 137.937 148.746 104.851 1.00 21.95 ? 355  LEU C CD2 1 
ATOM   10124 N N   . SER C 1 377 ? 135.581 149.114 109.541 1.00 23.82 ? 356  SER C N   1 
ATOM   10125 C CA  . SER C 1 377 ? 135.722 149.363 110.969 1.00 23.82 ? 356  SER C CA  1 
ATOM   10126 C C   . SER C 1 377 ? 136.203 148.114 111.693 1.00 23.82 ? 356  SER C C   1 
ATOM   10127 O O   . SER C 1 377 ? 137.151 148.167 112.487 1.00 23.82 ? 356  SER C O   1 
ATOM   10128 C CB  . SER C 1 377 ? 134.396 149.851 111.550 1.00 23.82 ? 356  SER C CB  1 
ATOM   10129 O OG  . SER C 1 377 ? 133.442 148.808 111.594 1.00 23.82 ? 356  SER C OG  1 
ATOM   10130 N N   . TYR C 1 378 ? 135.563 146.973 111.425 1.00 26.21 ? 357  TYR C N   1 
ATOM   10131 C CA  . TYR C 1 378 ? 135.997 145.734 112.061 1.00 26.21 ? 357  TYR C CA  1 
ATOM   10132 C C   . TYR C 1 378 ? 137.406 145.350 111.637 1.00 26.21 ? 357  TYR C C   1 
ATOM   10133 O O   . TYR C 1 378 ? 138.182 144.846 112.457 1.00 26.21 ? 357  TYR C O   1 
ATOM   10134 C CB  . TYR C 1 378 ? 135.018 144.608 111.747 1.00 26.21 ? 357  TYR C CB  1 
ATOM   10135 C CG  . TYR C 1 378 ? 133.999 144.389 112.834 1.00 26.21 ? 357  TYR C CG  1 
ATOM   10136 C CD1 . TYR C 1 378 ? 134.395 144.054 114.118 1.00 26.21 ? 357  TYR C CD1 1 
ATOM   10137 C CD2 . TYR C 1 378 ? 132.643 144.524 112.581 1.00 26.21 ? 357  TYR C CD2 1 
ATOM   10138 C CE1 . TYR C 1 378 ? 133.469 143.856 115.119 1.00 26.21 ? 357  TYR C CE1 1 
ATOM   10139 C CE2 . TYR C 1 378 ? 131.707 144.325 113.577 1.00 26.21 ? 357  TYR C CE2 1 
ATOM   10140 C CZ  . TYR C 1 378 ? 132.127 143.990 114.843 1.00 26.21 ? 357  TYR C CZ  1 
ATOM   10141 O OH  . TYR C 1 378 ? 131.202 143.793 115.841 1.00 26.21 ? 357  TYR C OH  1 
ATOM   10142 N N   . LEU C 1 379 ? 137.763 145.597 110.377 1.00 24.21 ? 358  LEU C N   1 
ATOM   10143 C CA  . LEU C 1 379 ? 139.107 145.288 109.912 1.00 24.21 ? 358  LEU C CA  1 
ATOM   10144 C C   . LEU C 1 379 ? 140.149 146.129 110.640 1.00 24.21 ? 358  LEU C C   1 
ATOM   10145 O O   . LEU C 1 379 ? 141.202 145.616 111.036 1.00 24.21 ? 358  LEU C O   1 
ATOM   10146 C CB  . LEU C 1 379 ? 139.178 145.506 108.402 1.00 24.21 ? 358  LEU C CB  1 
ATOM   10147 C CG  . LEU C 1 379 ? 140.407 145.049 107.624 1.00 24.21 ? 358  LEU C CG  1 
ATOM   10148 C CD1 . LEU C 1 379 ? 140.013 144.759 106.189 1.00 24.21 ? 358  LEU C CD1 1 
ATOM   10149 C CD2 . LEU C 1 379 ? 141.489 146.097 107.672 1.00 24.21 ? 358  LEU C CD2 1 
ATOM   10150 N N   . ASP C 1 380 ? 139.881 147.423 110.820 1.00 25.43 ? 359  ASP C N   1 
ATOM   10151 C CA  . ASP C 1 380 ? 140.823 148.274 111.538 1.00 25.43 ? 359  ASP C CA  1 
ATOM   10152 C C   . ASP C 1 380 ? 140.934 147.859 112.999 1.00 25.43 ? 359  ASP C C   1 
ATOM   10153 O O   . ASP C 1 380 ? 142.037 147.805 113.562 1.00 25.43 ? 359  ASP C O   1 
ATOM   10154 C CB  . ASP C 1 380 ? 140.403 149.737 111.427 1.00 25.43 ? 359  ASP C CB  1 
ATOM   10155 C CG  . ASP C 1 380 ? 141.484 150.685 111.894 1.00 25.43 ? 359  ASP C CG  1 
ATOM   10156 O OD1 . ASP C 1 380 ? 142.529 150.772 111.214 1.00 25.43 ? 359  ASP C OD1 1 
ATOM   10157 O OD2 . ASP C 1 380 ? 141.296 151.337 112.943 1.00 25.43 ? 359  ASP C OD2 1 
ATOM   10158 N N   . ILE C 1 381 ? 139.796 147.564 113.632 1.00 25.68 ? 360  ILE C N   1 
ATOM   10159 C CA  . ILE C 1 381 ? 139.817 147.122 115.023 1.00 25.68 ? 360  ILE C CA  1 
ATOM   10160 C C   . ILE C 1 381 ? 140.624 145.841 115.160 1.00 25.68 ? 360  ILE C C   1 
ATOM   10161 O O   . ILE C 1 381 ? 141.351 145.648 116.141 1.00 25.68 ? 360  ILE C O   1 
ATOM   10162 C CB  . ILE C 1 381 ? 138.381 146.960 115.552 1.00 25.68 ? 360  ILE C CB  1 
ATOM   10163 C CG1 . ILE C 1 381 ? 137.673 148.316 115.541 1.00 25.68 ? 360  ILE C CG1 1 
ATOM   10164 C CG2 . ILE C 1 381 ? 138.390 146.355 116.946 1.00 25.68 ? 360  ILE C CG2 1 
ATOM   10165 C CD1 . ILE C 1 381 ? 136.190 148.249 115.790 1.00 25.68 ? 360  ILE C CD1 1 
ATOM   10166 N N   . GLY C 1 382 ? 140.522 144.951 114.175 1.00 24.84 ? 361  GLY C N   1 
ATOM   10167 C CA  . GLY C 1 382 ? 141.371 143.774 114.184 1.00 24.84 ? 361  GLY C CA  1 
ATOM   10168 C C   . GLY C 1 382 ? 142.838 144.122 114.046 1.00 24.84 ? 361  GLY C C   1 
ATOM   10169 O O   . GLY C 1 382 ? 143.681 143.628 114.797 1.00 24.84 ? 361  GLY C O   1 
ATOM   10170 N N   . LYS C 1 383 ? 143.159 145.000 113.093 1.00 25.05 ? 362  LYS C N   1 
ATOM   10171 C CA  . LYS C 1 383 ? 144.551 145.372 112.861 1.00 25.05 ? 362  LYS C CA  1 
ATOM   10172 C C   . LYS C 1 383 ? 145.195 145.962 114.107 1.00 25.05 ? 362  LYS C C   1 
ATOM   10173 O O   . LYS C 1 383 ? 146.389 145.750 114.342 1.00 25.05 ? 362  LYS C O   1 
ATOM   10174 C CB  . LYS C 1 383 ? 144.647 146.361 111.702 1.00 25.05 ? 362  LYS C CB  1 
ATOM   10175 C CG  . LYS C 1 383 ? 145.165 145.759 110.410 1.00 25.05 ? 362  LYS C CG  1 
ATOM   10176 C CD  . LYS C 1 383 ? 145.052 146.750 109.263 1.00 25.05 ? 362  LYS C CD  1 
ATOM   10177 C CE  . LYS C 1 383 ? 145.160 146.056 107.918 1.00 25.05 ? 362  LYS C CE  1 
ATOM   10178 N NZ  . LYS C 1 383 ? 146.517 145.493 107.684 1.00 25.05 ? 362  LYS C NZ  1 
ATOM   10179 N N   . LYS C 1 384 ? 144.429 146.699 114.916 1.00 26.67 ? 363  LYS C N   1 
ATOM   10180 C CA  . LYS C 1 384 ? 145.000 147.300 116.120 1.00 26.67 ? 363  LYS C CA  1 
ATOM   10181 C C   . LYS C 1 384 ? 145.513 146.240 117.092 1.00 26.67 ? 363  LYS C C   1 
ATOM   10182 O O   . LYS C 1 384 ? 146.709 146.191 117.400 1.00 26.67 ? 363  LYS C O   1 
ATOM   10183 C CB  . LYS C 1 384 ? 143.981 148.213 116.805 1.00 26.67 ? 363  LYS C CB  1 
ATOM   10184 C CG  . LYS C 1 384 ? 143.671 149.491 116.041 1.00 26.67 ? 363  LYS C CG  1 
ATOM   10185 C CD  . LYS C 1 384 ? 142.823 150.434 116.884 1.00 26.67 ? 363  LYS C CD  1 
ATOM   10186 C CE  . LYS C 1 384 ? 141.387 149.969 117.009 1.00 26.67 ? 363  LYS C CE  1 
ATOM   10187 N NZ  . LYS C 1 384 ? 140.672 150.094 115.714 1.00 26.67 ? 363  LYS C NZ  1 
ATOM   10188 N N   . GLU C 1 385 ? 144.623 145.371 117.582 1.00 34.55 ? 364  GLU C N   1 
ATOM   10189 C CA  . GLU C 1 385 ? 144.978 144.453 118.664 1.00 34.55 ? 364  GLU C CA  1 
ATOM   10190 C C   . GLU C 1 385 ? 145.998 143.393 118.263 1.00 34.55 ? 364  GLU C C   1 
ATOM   10191 O O   . GLU C 1 385 ? 146.396 142.594 119.118 1.00 34.55 ? 364  GLU C O   1 
ATOM   10192 C CB  . GLU C 1 385 ? 143.727 143.765 119.211 1.00 34.55 ? 364  GLU C CB  1 
ATOM   10193 C CG  . GLU C 1 385 ? 142.803 144.682 119.984 1.00 34.55 ? 364  GLU C CG  1 
ATOM   10194 C CD  . GLU C 1 385 ? 141.696 143.929 120.693 1.00 34.55 ? 364  GLU C CD  1 
ATOM   10195 O OE1 . GLU C 1 385 ? 141.654 142.685 120.580 1.00 34.55 ? 364  GLU C OE1 1 
ATOM   10196 O OE2 . GLU C 1 385 ? 140.865 144.581 121.359 1.00 34.55 ? 364  GLU C OE2 1 
ATOM   10197 N N   . GLY C 1 386 ? 146.414 143.347 117.005 1.00 26.63 ? 365  GLY C N   1 
ATOM   10198 C CA  . GLY C 1 386 ? 147.437 142.422 116.562 1.00 26.63 ? 365  GLY C CA  1 
ATOM   10199 C C   . GLY C 1 386 ? 146.805 141.233 115.878 1.00 26.63 ? 365  GLY C C   1 
ATOM   10200 O O   . GLY C 1 386 ? 146.411 140.262 116.525 1.00 26.63 ? 365  GLY C O   1 
ATOM   10201 N N   . ALA C 1 387 ? 146.725 141.298 114.558 1.00 25.23 ? 366  ALA C N   1 
ATOM   10202 C CA  . ALA C 1 387 ? 145.937 140.364 113.773 1.00 25.23 ? 366  ALA C CA  1 
ATOM   10203 C C   . ALA C 1 387 ? 146.670 140.027 112.486 1.00 25.23 ? 366  ALA C C   1 
ATOM   10204 O O   . ALA C 1 387 ? 146.107 140.112 111.394 1.00 25.23 ? 366  ALA C O   1 
ATOM   10205 C CB  . ALA C 1 387 ? 144.550 140.930 113.493 1.00 25.23 ? 366  ALA C CB  1 
ATOM   10206 N N   . GLU C 1 388 ? 147.939 139.640 112.617 1.00 25.65 ? 367  GLU C N   1 
ATOM   10207 C CA  . GLU C 1 388 ? 148.926 139.692 111.545 1.00 25.65 ? 367  GLU C CA  1 
ATOM   10208 C C   . GLU C 1 388 ? 148.308 139.369 110.196 1.00 25.65 ? 367  GLU C C   1 
ATOM   10209 O O   . GLU C 1 388 ? 147.769 138.279 109.989 1.00 25.65 ? 367  GLU C O   1 
ATOM   10210 C CB  . GLU C 1 388 ? 150.040 138.693 111.849 1.00 25.65 ? 367  GLU C CB  1 
ATOM   10211 C CG  . GLU C 1 388 ? 150.880 139.034 113.056 1.00 25.65 ? 367  GLU C CG  1 
ATOM   10212 C CD  . GLU C 1 388 ? 151.947 137.995 113.315 1.00 25.65 ? 367  GLU C CD  1 
ATOM   10213 O OE1 . GLU C 1 388 ? 151.938 136.956 112.622 1.00 25.65 ? 367  GLU C OE1 1 
ATOM   10214 O OE2 . GLU C 1 388 ? 152.789 138.210 114.211 1.00 25.65 ? 367  GLU C OE2 1 
ATOM   10215 N N   . VAL C 1 389 ? 148.388 140.323 109.279 1.00 23.11 ? 368  VAL C N   1 
ATOM   10216 C CA  . VAL C 1 389 ? 147.714 140.223 107.993 1.00 23.11 ? 368  VAL C CA  1 
ATOM   10217 C C   . VAL C 1 389 ? 148.622 139.465 107.038 1.00 23.11 ? 368  VAL C C   1 
ATOM   10218 O O   . VAL C 1 389 ? 149.750 139.890 106.767 1.00 23.11 ? 368  VAL C O   1 
ATOM   10219 C CB  . VAL C 1 389 ? 147.357 141.612 107.443 1.00 23.11 ? 368  VAL C CB  1 
ATOM   10220 C CG1 . VAL C 1 389 ? 147.154 141.558 105.940 1.00 23.11 ? 368  VAL C CG1 1 
ATOM   10221 C CG2 . VAL C 1 389 ? 146.110 142.144 108.131 1.00 23.11 ? 368  VAL C CG2 1 
ATOM   10222 N N   . LEU C 1 390 ? 148.140 138.329 106.545 1.00 21.93 ? 369  LEU C N   1 
ATOM   10223 C CA  . LEU C 1 390 ? 148.884 137.568 105.557 1.00 21.93 ? 369  LEU C CA  1 
ATOM   10224 C C   . LEU C 1 390 ? 148.549 137.998 104.137 1.00 21.93 ? 369  LEU C C   1 
ATOM   10225 O O   . LEU C 1 390 ? 149.374 137.824 103.233 1.00 21.93 ? 369  LEU C O   1 
ATOM   10226 C CB  . LEU C 1 390 ? 148.621 136.071 105.741 1.00 21.93 ? 369  LEU C CB  1 
ATOM   10227 C CG  . LEU C 1 390 ? 149.195 135.464 107.029 1.00 21.93 ? 369  LEU C CG  1 
ATOM   10228 C CD1 . LEU C 1 390 ? 148.190 135.530 108.170 1.00 21.93 ? 369  LEU C CD1 1 
ATOM   10229 C CD2 . LEU C 1 390 ? 149.659 134.033 106.814 1.00 21.93 ? 369  LEU C CD2 1 
ATOM   10230 N N   . THR C 1 391 ? 147.364 138.565 103.928 1.00 20.14 ? 370  THR C N   1 
ATOM   10231 C CA  . THR C 1 391 ? 146.993 139.156 102.650 1.00 20.14 ? 370  THR C CA  1 
ATOM   10232 C C   . THR C 1 391 ? 145.815 140.095 102.867 1.00 20.14 ? 370  THR C C   1 
ATOM   10233 O O   . THR C 1 391 ? 145.093 139.994 103.862 1.00 20.14 ? 370  THR C O   1 
ATOM   10234 C CB  . THR C 1 391 ? 146.648 138.087 101.610 1.00 20.14 ? 370  THR C CB  1 
ATOM   10235 O OG1 . THR C 1 391 ? 146.301 138.719 100.372 1.00 20.14 ? 370  THR C OG1 1 
ATOM   10236 C CG2 . THR C 1 391 ? 145.493 137.239 102.086 1.00 20.14 ? 370  THR C CG2 1 
ATOM   10237 N N   . GLY C 1 392 ? 145.630 141.012 101.919 1.00 19.51 ? 371  GLY C N   1 
ATOM   10238 C CA  . GLY C 1 392 ? 144.507 141.929 101.990 1.00 19.51 ? 371  GLY C CA  1 
ATOM   10239 C C   . GLY C 1 392 ? 144.651 142.939 103.116 1.00 19.51 ? 371  GLY C C   1 
ATOM   10240 O O   . GLY C 1 392 ? 145.754 143.335 103.500 1.00 19.51 ? 371  GLY C O   1 
ATOM   10241 N N   . GLY C 1 393 ? 143.516 143.367 103.643 1.00 21.65 ? 372  GLY C N   1 
ATOM   10242 C CA  . GLY C 1 393 ? 143.473 144.242 104.790 1.00 21.65 ? 372  GLY C CA  1 
ATOM   10243 C C   . GLY C 1 393 ? 143.012 145.668 104.547 1.00 21.65 ? 372  GLY C C   1 
ATOM   10244 O O   . GLY C 1 393 ? 143.381 146.552 105.326 1.00 21.65 ? 372  GLY C O   1 
ATOM   10245 N N   . LYS C 1 394 ? 142.245 145.920 103.493 1.00 22.05 ? 373  LYS C N   1 
ATOM   10246 C CA  . LYS C 1 394 ? 141.745 147.255 103.192 1.00 22.05 ? 373  LYS C CA  1 
ATOM   10247 C C   . LYS C 1 394 ? 140.671 147.123 102.120 1.00 22.05 ? 373  LYS C C   1 
ATOM   10248 O O   . LYS C 1 394 ? 140.226 146.016 101.799 1.00 22.05 ? 373  LYS C O   1 
ATOM   10249 C CB  . LYS C 1 394 ? 142.884 148.183 102.759 1.00 22.05 ? 373  LYS C CB  1 
ATOM   10250 C CG  . LYS C 1 394 ? 143.630 147.706 101.537 1.00 22.05 ? 373  LYS C CG  1 
ATOM   10251 C CD  . LYS C 1 394 ? 145.103 148.039 101.621 1.00 22.05 ? 373  LYS C CD  1 
ATOM   10252 C CE  . LYS C 1 394 ? 145.775 147.867 100.270 1.00 22.05 ? 373  LYS C CE  1 
ATOM   10253 N NZ  . LYS C 1 394 ? 145.578 146.501 99.716  1.00 22.05 ? 373  LYS C NZ  1 
ATOM   10254 N N   . ALA C 1 395 ? 140.239 148.257 101.576 1.00 22.65 ? 374  ALA C N   1 
ATOM   10255 C CA  . ALA C 1 395 ? 139.386 148.254 100.399 1.00 22.65 ? 374  ALA C CA  1 
ATOM   10256 C C   . ALA C 1 395 ? 140.219 147.932 99.159  1.00 22.65 ? 374  ALA C C   1 
ATOM   10257 O O   . ALA C 1 395 ? 141.414 147.641 99.237  1.00 22.65 ? 374  ALA C O   1 
ATOM   10258 C CB  . ALA C 1 395 ? 138.675 149.595 100.254 1.00 22.65 ? 374  ALA C CB  1 
ATOM   10259 N N   . ALA C 1 396 ? 139.582 147.978 97.993  1.00 26.16 ? 375  ALA C N   1 
ATOM   10260 C CA  . ALA C 1 396 ? 140.256 147.711 96.725  1.00 26.16 ? 375  ALA C CA  1 
ATOM   10261 C C   . ALA C 1 396 ? 139.676 148.626 95.656  1.00 26.16 ? 375  ALA C C   1 
ATOM   10262 O O   . ALA C 1 396 ? 138.516 148.470 95.263  1.00 26.16 ? 375  ALA C O   1 
ATOM   10263 C CB  . ALA C 1 396 ? 140.112 146.245 96.320  1.00 26.16 ? 375  ALA C CB  1 
ATOM   10264 N N   . ASP C 1 397 ? 140.479 149.578 95.189  1.00 30.59 ? 376  ASP C N   1 
ATOM   10265 C CA  . ASP C 1 397 ? 140.092 150.447 94.080  1.00 30.59 ? 376  ASP C CA  1 
ATOM   10266 C C   . ASP C 1 397 ? 140.551 149.775 92.793  1.00 30.59 ? 376  ASP C C   1 
ATOM   10267 O O   . ASP C 1 397 ? 141.741 149.763 92.473  1.00 30.59 ? 376  ASP C O   1 
ATOM   10268 C CB  . ASP C 1 397 ? 140.697 151.837 94.242  1.00 30.59 ? 376  ASP C CB  1 
ATOM   10269 C CG  . ASP C 1 397 ? 139.988 152.881 93.402  1.00 30.59 ? 376  ASP C CG  1 
ATOM   10270 O OD1 . ASP C 1 397 ? 138.743 152.832 93.316  1.00 30.59 ? 376  ASP C OD1 1 
ATOM   10271 O OD2 . ASP C 1 397 ? 140.675 153.752 92.830  1.00 30.59 ? 376  ASP C OD2 1 
ATOM   10272 N N   . LEU C 1 398 ? 139.602 149.208 92.054  1.00 30.10 ? 377  LEU C N   1 
ATOM   10273 C CA  . LEU C 1 398 ? 139.920 148.405 90.882  1.00 30.10 ? 377  LEU C CA  1 
ATOM   10274 C C   . LEU C 1 398 ? 140.013 149.216 89.596  1.00 30.10 ? 377  LEU C C   1 
ATOM   10275 O O   . LEU C 1 398 ? 140.419 148.666 88.566  1.00 30.10 ? 377  LEU C O   1 
ATOM   10276 C CB  . LEU C 1 398 ? 138.880 147.294 90.723  1.00 30.10 ? 377  LEU C CB  1 
ATOM   10277 C CG  . LEU C 1 398 ? 138.820 146.331 91.912  1.00 30.10 ? 377  LEU C CG  1 
ATOM   10278 C CD1 . LEU C 1 398 ? 137.566 145.496 91.854  1.00 30.10 ? 377  LEU C CD1 1 
ATOM   10279 C CD2 . LEU C 1 398 ? 140.050 145.441 91.959  1.00 30.10 ? 377  LEU C CD2 1 
ATOM   10280 N N   . GLY C 1 399 ? 139.652 150.497 89.626  1.00 28.61 ? 378  GLY C N   1 
ATOM   10281 C CA  . GLY C 1 399 ? 139.828 151.355 88.471  1.00 28.61 ? 378  GLY C CA  1 
ATOM   10282 C C   . GLY C 1 399 ? 138.760 151.165 87.408  1.00 28.61 ? 378  GLY C C   1 
ATOM   10283 O O   . GLY C 1 399 ? 137.800 150.403 87.564  1.00 28.61 ? 378  GLY C O   1 
ATOM   10284 N N   . GLY C 1 400 ? 138.952 151.869 86.295  1.00 30.78 ? 379  GLY C N   1 
ATOM   10285 C CA  . GLY C 1 400 ? 137.956 151.861 85.236  1.00 30.78 ? 379  GLY C CA  1 
ATOM   10286 C C   . GLY C 1 400 ? 136.663 152.492 85.711  1.00 30.78 ? 379  GLY C C   1 
ATOM   10287 O O   . GLY C 1 400 ? 136.662 153.527 86.385  1.00 30.78 ? 379  GLY C O   1 
ATOM   10288 N N   . GLU C 1 401 ? 135.542 151.866 85.357  1.00 32.28 ? 380  GLU C N   1 
ATOM   10289 C CA  . GLU C 1 401 ? 134.246 152.262 85.893  1.00 32.28 ? 380  GLU C CA  1 
ATOM   10290 C C   . GLU C 1 401 ? 134.075 151.863 87.352  1.00 32.28 ? 380  GLU C C   1 
ATOM   10291 O O   . GLU C 1 401 ? 133.079 152.248 87.973  1.00 32.28 ? 380  GLU C O   1 
ATOM   10292 C CB  . GLU C 1 401 ? 133.115 151.636 85.072  1.00 32.28 ? 380  GLU C CB  1 
ATOM   10293 C CG  . GLU C 1 401 ? 133.107 152.005 83.597  1.00 32.28 ? 380  GLU C CG  1 
ATOM   10294 C CD  . GLU C 1 401 ? 131.784 151.677 82.926  1.00 32.28 ? 380  GLU C CD  1 
ATOM   10295 O OE1 . GLU C 1 401 ? 131.481 150.477 82.755  1.00 32.28 ? 380  GLU C OE1 1 
ATOM   10296 O OE2 . GLU C 1 401 ? 131.045 152.620 82.572  1.00 32.28 ? 380  GLU C OE2 1 
ATOM   10297 N N   . LEU C 1 402 ? 135.018 151.102 87.901  1.00 29.34 ? 381  LEU C N   1 
ATOM   10298 C CA  . LEU C 1 402 ? 134.856 150.464 89.202  1.00 29.34 ? 381  LEU C CA  1 
ATOM   10299 C C   . LEU C 1 402 ? 135.564 151.288 90.276  1.00 29.34 ? 381  LEU C C   1 
ATOM   10300 O O   . LEU C 1 402 ? 136.601 150.908 90.819  1.00 29.34 ? 381  LEU C O   1 
ATOM   10301 C CB  . LEU C 1 402 ? 135.399 149.044 89.148  1.00 29.34 ? 381  LEU C CB  1 
ATOM   10302 C CG  . LEU C 1 402 ? 134.639 148.097 88.223  1.00 29.34 ? 381  LEU C CG  1 
ATOM   10303 C CD1 . LEU C 1 402 ? 135.360 146.769 88.154  1.00 29.34 ? 381  LEU C CD1 1 
ATOM   10304 C CD2 . LEU C 1 402 ? 133.192 147.929 88.649  1.00 29.34 ? 381  LEU C CD2 1 
ATOM   10305 N N   . SER C 1 403 ? 134.982 152.430 90.575  1.00 28.79 ? 382  SER C N   1 
ATOM   10306 C CA  . SER C 1 403 ? 135.487 153.258 91.664  1.00 28.79 ? 382  SER C CA  1 
ATOM   10307 C C   . SER C 1 403 ? 134.410 153.601 92.679  1.00 28.79 ? 382  SER C C   1 
ATOM   10308 O O   . SER C 1 403 ? 134.699 153.670 93.875  1.00 28.79 ? 382  SER C O   1 
ATOM   10309 C CB  . SER C 1 403 ? 136.112 154.550 91.111  1.00 28.79 ? 382  SER C CB  1 
ATOM   10310 O OG  . SER C 1 403 ? 135.126 155.540 90.875  1.00 28.79 ? 382  SER C OG  1 
ATOM   10311 N N   . GLY C 1 404 ? 133.177 153.811 92.235  1.00 23.98 ? 383  GLY C N   1 
ATOM   10312 C CA  . GLY C 1 404 ? 132.078 154.055 93.139  1.00 23.98 ? 383  GLY C CA  1 
ATOM   10313 C C   . GLY C 1 404 ? 131.532 152.820 93.800  1.00 23.98 ? 383  GLY C C   1 
ATOM   10314 O O   . GLY C 1 404 ? 130.594 152.911 94.596  1.00 23.98 ? 383  GLY C O   1 
ATOM   10315 N N   . GLY C 1 405 ? 132.102 151.657 93.489  1.00 21.22 ? 384  GLY C N   1 
ATOM   10316 C CA  . GLY C 1 405 ? 131.655 150.402 94.053  1.00 21.22 ? 384  GLY C CA  1 
ATOM   10317 C C   . GLY C 1 405 ? 131.958 150.268 95.529  1.00 21.22 ? 384  GLY C C   1 
ATOM   10318 O O   . GLY C 1 405 ? 132.270 151.255 96.200  1.00 21.22 ? 384  GLY C O   1 
ATOM   10319 N N   . TYR C 1 406 ? 131.857 149.051 96.055  1.00 20.46 ? 385  TYR C N   1 
ATOM   10320 C CA  . TYR C 1 406 ? 132.023 148.831 97.484  1.00 20.46 ? 385  TYR C CA  1 
ATOM   10321 C C   . TYR C 1 406 ? 132.844 147.577 97.751  1.00 20.46 ? 385  TYR C C   1 
ATOM   10322 O O   . TYR C 1 406 ? 132.515 146.774 98.628  1.00 20.46 ? 385  TYR C O   1 
ATOM   10323 C CB  . TYR C 1 406 ? 130.666 148.779 98.179  1.00 20.46 ? 385  TYR C CB  1 
ATOM   10324 C CG  . TYR C 1 406 ? 129.826 149.987 97.842  1.00 20.46 ? 385  TYR C CG  1 
ATOM   10325 C CD1 . TYR C 1 406 ? 129.947 151.166 98.565  1.00 20.46 ? 385  TYR C CD1 1 
ATOM   10326 C CD2 . TYR C 1 406 ? 128.940 149.964 96.777  1.00 20.46 ? 385  TYR C CD2 1 
ATOM   10327 C CE1 . TYR C 1 406 ? 129.196 152.275 98.248  1.00 20.46 ? 385  TYR C CE1 1 
ATOM   10328 C CE2 . TYR C 1 406 ? 128.186 151.071 96.453  1.00 20.46 ? 385  TYR C CE2 1 
ATOM   10329 C CZ  . TYR C 1 406 ? 128.316 152.222 97.191  1.00 20.46 ? 385  TYR C CZ  1 
ATOM   10330 O OH  . TYR C 1 406 ? 127.562 153.324 96.870  1.00 20.46 ? 385  TYR C OH  1 
ATOM   10331 N N   . TYR C 1 407 ? 133.937 147.407 97.012  1.00 20.91 ? 386  TYR C N   1 
ATOM   10332 C CA  . TYR C 1 407 ? 134.765 146.216 97.141  1.00 20.91 ? 386  TYR C CA  1 
ATOM   10333 C C   . TYR C 1 407 ? 135.600 146.227 98.417  1.00 20.91 ? 386  TYR C C   1 
ATOM   10334 O O   . TYR C 1 407 ? 136.077 147.273 98.865  1.00 20.91 ? 386  TYR C O   1 
ATOM   10335 C CB  . TYR C 1 407 ? 135.693 146.076 95.938  1.00 20.91 ? 386  TYR C CB  1 
ATOM   10336 C CG  . TYR C 1 407 ? 134.987 146.040 94.609  1.00 20.91 ? 386  TYR C CG  1 
ATOM   10337 C CD1 . TYR C 1 407 ? 134.448 147.188 94.046  1.00 20.91 ? 386  TYR C CD1 1 
ATOM   10338 C CD2 . TYR C 1 407 ? 134.852 144.849 93.917  1.00 20.91 ? 386  TYR C CD2 1 
ATOM   10339 C CE1 . TYR C 1 407 ? 133.803 147.149 92.832  1.00 20.91 ? 386  TYR C CE1 1 
ATOM   10340 C CE2 . TYR C 1 407 ? 134.210 144.803 92.706  1.00 20.91 ? 386  TYR C CE2 1 
ATOM   10341 C CZ  . TYR C 1 407 ? 133.690 145.954 92.168  1.00 20.91 ? 386  TYR C CZ  1 
ATOM   10342 O OH  . TYR C 1 407 ? 133.048 145.900 90.961  1.00 20.91 ? 386  TYR C OH  1 
ATOM   10343 N N   . ILE C 1 408 ? 135.778 145.039 98.991  1.00 21.00 ? 387  ILE C N   1 
ATOM   10344 C CA  . ILE C 1 408 ? 136.719 144.778 100.072 1.00 21.00 ? 387  ILE C CA  1 
ATOM   10345 C C   . ILE C 1 408 ? 137.620 143.638 99.622  1.00 21.00 ? 387  ILE C C   1 
ATOM   10346 O O   . ILE C 1 408 ? 137.138 142.643 99.072  1.00 21.00 ? 387  ILE C O   1 
ATOM   10347 C CB  . ILE C 1 408 ? 136.000 144.415 101.386 1.00 21.00 ? 387  ILE C CB  1 
ATOM   10348 C CG1 . ILE C 1 408 ? 135.101 145.560 101.848 1.00 21.00 ? 387  ILE C CG1 1 
ATOM   10349 C CG2 . ILE C 1 408 ? 137.005 144.073 102.470 1.00 21.00 ? 387  ILE C CG2 1 
ATOM   10350 C CD1 . ILE C 1 408 ? 135.850 146.813 102.183 1.00 21.00 ? 387  ILE C CD1 1 
ATOM   10351 N N   . GLU C 1 409 ? 138.923 143.782 99.841  1.00 21.58 ? 388  GLU C N   1 
ATOM   10352 C CA  . GLU C 1 409 ? 139.674 142.658 99.299  1.00 21.58 ? 388  GLU C CA  1 
ATOM   10353 C C   . GLU C 1 409 ? 139.800 141.541 100.331 1.00 21.58 ? 388  GLU C C   1 
ATOM   10354 O O   . GLU C 1 409 ? 139.784 141.800 101.539 1.00 21.58 ? 388  GLU C O   1 
ATOM   10355 C CB  . GLU C 1 409 ? 141.062 143.108 98.856  1.00 21.58 ? 388  GLU C CB  1 
ATOM   10356 C CG  . GLU C 1 409 ? 141.830 143.883 99.894  1.00 21.58 ? 388  GLU C CG  1 
ATOM   10357 C CD  . GLU C 1 409 ? 143.279 144.069 99.505  1.00 21.58 ? 388  GLU C CD  1 
ATOM   10358 O OE1 . GLU C 1 409 ? 143.725 143.405 98.545  1.00 21.58 ? 388  GLU C OE1 1 
ATOM   10359 O OE2 . GLU C 1 409 ? 143.973 144.876 100.156 1.00 21.58 ? 388  GLU C OE2 1 
ATOM   10360 N N   . PRO C 1 410 ? 139.924 140.290 99.880  1.00 17.84 ? 389  PRO C N   1 
ATOM   10361 C CA  . PRO C 1 410 ? 139.944 139.155 100.819 1.00 17.84 ? 389  PRO C CA  1 
ATOM   10362 C C   . PRO C 1 410 ? 141.124 139.234 101.773 1.00 17.84 ? 389  PRO C C   1 
ATOM   10363 O O   . PRO C 1 410 ? 142.281 139.293 101.356 1.00 17.84 ? 389  PRO C O   1 
ATOM   10364 C CB  . PRO C 1 410 ? 140.048 137.936 99.894  1.00 17.84 ? 389  PRO C CB  1 
ATOM   10365 C CG  . PRO C 1 410 ? 139.611 138.419 98.563  1.00 17.84 ? 389  PRO C CG  1 
ATOM   10366 C CD  . PRO C 1 410 ? 140.022 139.844 98.483  1.00 17.84 ? 389  PRO C CD  1 
ATOM   10367 N N   . THR C 1 411 ? 140.822 139.220 103.068 1.00 18.74 ? 390  THR C N   1 
ATOM   10368 C CA  . THR C 1 411 ? 141.822 139.420 104.108 1.00 18.74 ? 390  THR C CA  1 
ATOM   10369 C C   . THR C 1 411 ? 141.941 138.168 104.961 1.00 18.74 ? 390  THR C C   1 
ATOM   10370 O O   . THR C 1 411 ? 140.957 137.731 105.566 1.00 18.74 ? 390  THR C O   1 
ATOM   10371 C CB  . THR C 1 411 ? 141.465 140.614 104.989 1.00 18.74 ? 390  THR C CB  1 
ATOM   10372 O OG1 . THR C 1 411 ? 141.115 141.734 104.167 1.00 18.74 ? 390  THR C OG1 1 
ATOM   10373 C CG2 . THR C 1 411 ? 142.646 140.979 105.855 1.00 18.74 ? 390  THR C CG2 1 
ATOM   10374 N N   . ILE C 1 412 ? 143.144 137.607 105.024 1.00 18.45 ? 391  ILE C N   1 
ATOM   10375 C CA  . ILE C 1 412 ? 143.457 136.549 105.976 1.00 18.45 ? 391  ILE C CA  1 
ATOM   10376 C C   . ILE C 1 412 ? 144.005 137.198 107.239 1.00 18.45 ? 391  ILE C C   1 
ATOM   10377 O O   . ILE C 1 412 ? 145.084 137.798 107.223 1.00 18.45 ? 391  ILE C O   1 
ATOM   10378 C CB  . ILE C 1 412 ? 144.462 135.546 105.395 1.00 18.45 ? 391  ILE C CB  1 
ATOM   10379 C CG1 . ILE C 1 412 ? 143.841 134.754 104.251 1.00 18.45 ? 391  ILE C CG1 1 
ATOM   10380 C CG2 . ILE C 1 412 ? 144.937 134.596 106.471 1.00 18.45 ? 391  ILE C CG2 1 
ATOM   10381 C CD1 . ILE C 1 412 ? 144.742 133.656 103.738 1.00 18.45 ? 391  ILE C CD1 1 
ATOM   10382 N N   . PHE C 1 413 ? 143.261 137.089 108.329 1.00 21.65 ? 392  PHE C N   1 
ATOM   10383 C CA  . PHE C 1 413 ? 143.709 137.581 109.619 1.00 21.65 ? 392  PHE C CA  1 
ATOM   10384 C C   . PHE C 1 413 ? 144.560 136.492 110.270 1.00 21.65 ? 392  PHE C C   1 
ATOM   10385 O O   . PHE C 1 413 ? 144.867 135.471 109.651 1.00 21.65 ? 392  PHE C O   1 
ATOM   10386 C CB  . PHE C 1 413 ? 142.502 137.976 110.466 1.00 21.65 ? 392  PHE C CB  1 
ATOM   10387 C CG  . PHE C 1 413 ? 142.169 139.440 110.407 1.00 21.65 ? 392  PHE C CG  1 
ATOM   10388 C CD1 . PHE C 1 413 ? 142.048 140.087 109.193 1.00 21.65 ? 392  PHE C CD1 1 
ATOM   10389 C CD2 . PHE C 1 413 ? 141.946 140.162 111.561 1.00 21.65 ? 392  PHE C CD2 1 
ATOM   10390 C CE1 . PHE C 1 413 ? 141.737 141.429 109.140 1.00 21.65 ? 392  PHE C CE1 1 
ATOM   10391 C CE2 . PHE C 1 413 ? 141.636 141.500 111.513 1.00 21.65 ? 392  PHE C CE2 1 
ATOM   10392 C CZ  . PHE C 1 413 ? 141.530 142.134 110.302 1.00 21.65 ? 392  PHE C CZ  1 
ATOM   10393 N N   . ARG C 1 414 ? 144.953 136.693 111.525 1.00 19.93 ? 393  ARG C N   1 
ATOM   10394 C CA  . ARG C 1 414 ? 145.691 135.673 112.261 1.00 19.93 ? 393  ARG C CA  1 
ATOM   10395 C C   . ARG C 1 414 ? 145.724 136.024 113.740 1.00 19.93 ? 393  ARG C C   1 
ATOM   10396 O O   . ARG C 1 414 ? 146.064 137.152 114.103 1.00 19.93 ? 393  ARG C O   1 
ATOM   10397 C CB  . ARG C 1 414 ? 147.113 135.529 111.716 1.00 19.93 ? 393  ARG C CB  1 
ATOM   10398 C CG  . ARG C 1 414 ? 148.053 134.750 112.611 1.00 19.93 ? 393  ARG C CG  1 
ATOM   10399 C CD  . ARG C 1 414 ? 147.804 133.259 112.503 1.00 19.93 ? 393  ARG C CD  1 
ATOM   10400 N NE  . ARG C 1 414 ? 148.903 132.474 113.062 1.00 19.93 ? 393  ARG C NE  1 
ATOM   10401 C CZ  . ARG C 1 414 ? 148.979 132.086 114.331 1.00 19.93 ? 393  ARG C CZ  1 
ATOM   10402 N NH1 . ARG C 1 414 ? 148.016 132.404 115.186 1.00 19.93 ? 393  ARG C NH1 1 
ATOM   10403 N NH2 . ARG C 1 414 ? 150.017 131.373 114.745 1.00 19.93 ? 393  ARG C NH2 1 
ATOM   10404 N N   . GLY C 1 415 ? 145.379 135.076 114.603 1.00 17.62 ? 394  GLY C N   1 
ATOM   10405 C CA  . GLY C 1 415 ? 145.385 135.363 116.021 1.00 17.62 ? 394  GLY C CA  1 
ATOM   10406 C C   . GLY C 1 415 ? 144.867 134.236 116.885 1.00 17.62 ? 394  GLY C C   1 
ATOM   10407 O O   . GLY C 1 415 ? 145.201 133.069 116.671 1.00 17.62 ? 394  GLY C O   1 
ATOM   10408 N N   . ASN C 1 416 ? 144.046 134.585 117.871 1.00 22.56 ? 395  ASN C N   1 
ATOM   10409 C CA  . ASN C 1 416 ? 143.533 133.623 118.831 1.00 22.56 ? 395  ASN C CA  1 
ATOM   10410 C C   . ASN C 1 416 ? 142.107 134.004 119.185 1.00 22.56 ? 395  ASN C C   1 
ATOM   10411 O O   . ASN C 1 416 ? 141.702 135.160 119.048 1.00 22.56 ? 395  ASN C O   1 
ATOM   10412 C CB  . ASN C 1 416 ? 144.410 133.567 120.085 1.00 22.56 ? 395  ASN C CB  1 
ATOM   10413 C CG  . ASN C 1 416 ? 144.826 134.940 120.561 1.00 22.56 ? 395  ASN C CG  1 
ATOM   10414 O OD1 . ASN C 1 416 ? 144.001 135.728 121.021 1.00 22.56 ? 395  ASN C OD1 1 
ATOM   10415 N ND2 . ASN C 1 416 ? 146.113 135.241 120.440 1.00 22.56 ? 395  ASN C ND2 1 
ATOM   10416 N N   . ASN C 1 417 ? 141.349 133.018 119.661 1.00 21.37 ? 396  ASN C N   1 
ATOM   10417 C CA  . ASN C 1 417 ? 139.923 133.209 119.897 1.00 21.37 ? 396  ASN C CA  1 
ATOM   10418 C C   . ASN C 1 417 ? 139.624 134.190 121.018 1.00 21.37 ? 396  ASN C C   1 
ATOM   10419 O O   . ASN C 1 417 ? 138.447 134.461 121.273 1.00 21.37 ? 396  ASN C O   1 
ATOM   10420 C CB  . ASN C 1 417 ? 139.259 131.864 120.189 1.00 21.37 ? 396  ASN C CB  1 
ATOM   10421 C CG  . ASN C 1 417 ? 138.793 131.168 118.930 1.00 21.37 ? 396  ASN C CG  1 
ATOM   10422 O OD1 . ASN C 1 417 ? 137.604 131.166 118.613 1.00 21.37 ? 396  ASN C OD1 1 
ATOM   10423 N ND2 . ASN C 1 417 ? 139.733 130.591 118.190 1.00 21.37 ? 396  ASN C ND2 1 
ATOM   10424 N N   . LYS C 1 418 ? 140.638 134.722 121.695 1.00 23.62 ? 397  LYS C N   1 
ATOM   10425 C CA  . LYS C 1 418 ? 140.397 135.804 122.638 1.00 23.62 ? 397  LYS C CA  1 
ATOM   10426 C C   . LYS C 1 418 ? 140.103 137.113 121.921 1.00 23.62 ? 397  LYS C C   1 
ATOM   10427 O O   . LYS C 1 418 ? 139.295 137.914 122.403 1.00 23.62 ? 397  LYS C O   1 
ATOM   10428 C CB  . LYS C 1 418 ? 141.602 135.976 123.565 1.00 23.62 ? 397  LYS C CB  1 
ATOM   10429 C CG  . LYS C 1 418 ? 142.335 134.687 123.888 1.00 23.62 ? 397  LYS C CG  1 
ATOM   10430 C CD  . LYS C 1 418 ? 141.470 133.747 124.711 1.00 23.62 ? 397  LYS C CD  1 
ATOM   10431 C CE  . LYS C 1 418 ? 142.070 132.357 124.756 1.00 23.62 ? 397  LYS C CE  1 
ATOM   10432 N NZ  . LYS C 1 418 ? 143.549 132.408 124.912 1.00 23.62 ? 397  LYS C NZ  1 
ATOM   10433 N N   . MET C 1 419 ? 140.738 137.333 120.774 1.00 26.45 ? 398  MET C N   1 
ATOM   10434 C CA  . MET C 1 419 ? 140.624 138.583 120.047 1.00 26.45 ? 398  MET C CA  1 
ATOM   10435 C C   . MET C 1 419 ? 139.190 138.798 119.576 1.00 26.45 ? 398  MET C C   1 
ATOM   10436 O O   . MET C 1 419 ? 138.429 137.852 119.362 1.00 26.45 ? 398  MET C O   1 
ATOM   10437 C CB  . MET C 1 419 ? 141.583 138.582 118.861 1.00 26.45 ? 398  MET C CB  1 
ATOM   10438 C CG  . MET C 1 419 ? 143.031 138.751 119.276 1.00 26.45 ? 398  MET C CG  1 
ATOM   10439 S SD  . MET C 1 419 ? 144.168 138.759 117.888 1.00 26.45 ? 398  MET C SD  1 
ATOM   10440 C CE  . MET C 1 419 ? 143.189 139.611 116.661 1.00 26.45 ? 398  MET C CE  1 
ATOM   10441 N N   . ARG C 1 420 ? 138.819 140.070 119.420 1.00 28.90 ? 399  ARG C N   1 
ATOM   10442 C CA  . ARG C 1 420 ? 137.415 140.385 119.184 1.00 28.90 ? 399  ARG C CA  1 
ATOM   10443 C C   . ARG C 1 420 ? 137.004 140.109 117.743 1.00 28.90 ? 399  ARG C C   1 
ATOM   10444 O O   . ARG C 1 420 ? 135.808 140.056 117.444 1.00 28.90 ? 399  ARG C O   1 
ATOM   10445 C CB  . ARG C 1 420 ? 137.130 141.836 119.569 1.00 28.90 ? 399  ARG C CB  1 
ATOM   10446 C CG  . ARG C 1 420 ? 135.669 142.087 119.904 1.00 28.90 ? 399  ARG C CG  1 
ATOM   10447 C CD  . ARG C 1 420 ? 135.420 143.512 120.359 1.00 28.90 ? 399  ARG C CD  1 
ATOM   10448 N NE  . ARG C 1 420 ? 135.465 144.469 119.260 1.00 28.90 ? 399  ARG C NE  1 
ATOM   10449 C CZ  . ARG C 1 420 ? 135.394 145.785 119.421 1.00 28.90 ? 399  ARG C CZ  1 
ATOM   10450 N NH1 . ARG C 1 420 ? 135.277 146.302 120.636 1.00 28.90 ? 399  ARG C NH1 1 
ATOM   10451 N NH2 . ARG C 1 420 ? 135.435 146.584 118.368 1.00 28.90 ? 399  ARG C NH2 1 
ATOM   10452 N N   . ILE C 1 421 ? 137.970 139.927 116.839 1.00 23.55 ? 400  ILE C N   1 
ATOM   10453 C CA  . ILE C 1 421 ? 137.650 139.501 115.482 1.00 23.55 ? 400  ILE C CA  1 
ATOM   10454 C C   . ILE C 1 421 ? 137.116 138.082 115.418 1.00 23.55 ? 400  ILE C C   1 
ATOM   10455 O O   . ILE C 1 421 ? 136.535 137.693 114.400 1.00 23.55 ? 400  ILE C O   1 
ATOM   10456 C CB  . ILE C 1 421 ? 138.876 139.564 114.557 1.00 23.55 ? 400  ILE C CB  1 
ATOM   10457 C CG1 . ILE C 1 421 ? 139.957 138.631 115.095 1.00 23.55 ? 400  ILE C CG1 1 
ATOM   10458 C CG2 . ILE C 1 421 ? 139.369 140.971 114.450 1.00 23.55 ? 400  ILE C CG2 1 
ATOM   10459 C CD1 . ILE C 1 421 ? 141.068 138.333 114.131 1.00 23.55 ? 400  ILE C CD1 1 
ATOM   10460 N N   . PHE C 1 422 ? 137.320 137.289 116.466 1.00 21.57 ? 401  PHE C N   1 
ATOM   10461 C CA  . PHE C 1 422 ? 136.827 135.922 116.499 1.00 21.57 ? 401  PHE C CA  1 
ATOM   10462 C C   . PHE C 1 422 ? 135.421 135.811 117.065 1.00 21.57 ? 401  PHE C C   1 
ATOM   10463 O O   . PHE C 1 422 ? 134.667 134.929 116.648 1.00 21.57 ? 401  PHE C O   1 
ATOM   10464 C CB  . PHE C 1 422 ? 137.776 135.041 117.316 1.00 21.57 ? 401  PHE C CB  1 
ATOM   10465 C CG  . PHE C 1 422 ? 139.022 134.642 116.578 1.00 21.57 ? 401  PHE C CG  1 
ATOM   10466 C CD1 . PHE C 1 422 ? 140.082 135.518 116.460 1.00 21.57 ? 401  PHE C CD1 1 
ATOM   10467 C CD2 . PHE C 1 422 ? 139.133 133.390 116.005 1.00 21.57 ? 401  PHE C CD2 1 
ATOM   10468 C CE1 . PHE C 1 422 ? 141.222 135.157 115.789 1.00 21.57 ? 401  PHE C CE1 1 
ATOM   10469 C CE2 . PHE C 1 422 ? 140.273 133.024 115.334 1.00 21.57 ? 401  PHE C CE2 1 
ATOM   10470 C CZ  . PHE C 1 422 ? 141.317 133.907 115.226 1.00 21.57 ? 401  PHE C CZ  1 
ATOM   10471 N N   . GLN C 1 423 ? 135.045 136.692 117.989 1.00 25.57 ? 402  GLN C N   1 
ATOM   10472 C CA  . GLN C 1 423 ? 133.723 136.677 118.602 1.00 25.57 ? 402  GLN C CA  1 
ATOM   10473 C C   . GLN C 1 423 ? 132.812 137.764 118.040 1.00 25.57 ? 402  GLN C C   1 
ATOM   10474 O O   . GLN C 1 423 ? 131.763 138.059 118.617 1.00 25.57 ? 402  GLN C O   1 
ATOM   10475 C CB  . GLN C 1 423 ? 133.837 136.806 120.120 1.00 25.57 ? 402  GLN C CB  1 
ATOM   10476 C CG  . GLN C 1 423 ? 133.963 135.476 120.853 1.00 25.57 ? 402  GLN C CG  1 
ATOM   10477 C CD  . GLN C 1 423 ? 135.281 134.773 120.592 1.00 25.57 ? 402  GLN C CD  1 
ATOM   10478 O OE1 . GLN C 1 423 ? 136.193 135.342 120.001 1.00 25.57 ? 402  GLN C OE1 1 
ATOM   10479 N NE2 . GLN C 1 423 ? 135.386 133.530 121.039 1.00 25.57 ? 402  GLN C NE2 1 
ATOM   10480 N N   . GLU C 1 424 ? 133.195 138.363 116.914 1.00 29.96 ? 403  GLU C N   1 
ATOM   10481 C CA  . GLU C 1 424 ? 132.367 139.354 116.241 1.00 29.96 ? 403  GLU C CA  1 
ATOM   10482 C C   . GLU C 1 424 ? 132.413 139.098 114.743 1.00 29.96 ? 403  GLU C C   1 
ATOM   10483 O O   . GLU C 1 424 ? 133.475 138.792 114.195 1.00 29.96 ? 403  GLU C O   1 
ATOM   10484 C CB  . GLU C 1 424 ? 132.832 140.778 116.555 1.00 29.96 ? 403  GLU C CB  1 
ATOM   10485 C CG  . GLU C 1 424 ? 132.475 141.252 117.954 1.00 29.96 ? 403  GLU C CG  1 
ATOM   10486 C CD  . GLU C 1 424 ? 131.005 141.586 118.099 1.00 29.96 ? 403  GLU C CD  1 
ATOM   10487 O OE1 . GLU C 1 424 ? 130.248 140.735 118.610 1.00 29.96 ? 403  GLU C OE1 1 
ATOM   10488 O OE2 . GLU C 1 424 ? 130.605 142.700 117.701 1.00 29.96 ? 403  GLU C OE2 1 
ATOM   10489 N N   . GLU C 1 425 ? 131.266 139.234 114.084 1.00 26.73 ? 404  GLU C N   1 
ATOM   10490 C CA  . GLU C 1 425 ? 131.105 138.819 112.696 1.00 26.73 ? 404  GLU C CA  1 
ATOM   10491 C C   . GLU C 1 425 ? 131.114 140.023 111.762 1.00 26.73 ? 404  GLU C C   1 
ATOM   10492 O O   . GLU C 1 425 ? 130.450 141.029 112.027 1.00 26.73 ? 404  GLU C O   1 
ATOM   10493 C CB  . GLU C 1 425 ? 129.819 138.012 112.524 1.00 26.73 ? 404  GLU C CB  1 
ATOM   10494 C CG  . GLU C 1 425 ? 129.707 137.316 111.182 1.00 26.73 ? 404  GLU C CG  1 
ATOM   10495 C CD  . GLU C 1 425 ? 128.272 137.062 110.791 1.00 26.73 ? 404  GLU C CD  1 
ATOM   10496 O OE1 . GLU C 1 425 ? 127.405 137.853 111.209 1.00 26.73 ? 404  GLU C OE1 1 
ATOM   10497 O OE2 . GLU C 1 425 ? 128.013 136.085 110.059 1.00 26.73 ? 404  GLU C OE2 1 
ATOM   10498 N N   . ILE C 1 426 ? 131.856 139.903 110.665 1.00 24.60 ? 405  ILE C N   1 
ATOM   10499 C CA  . ILE C 1 426 ? 132.166 141.040 109.805 1.00 24.60 ? 405  ILE C CA  1 
ATOM   10500 C C   . ILE C 1 426 ? 131.172 141.174 108.653 1.00 24.60 ? 405  ILE C C   1 
ATOM   10501 O O   . ILE C 1 426 ? 130.863 142.291 108.229 1.00 24.60 ? 405  ILE C O   1 
ATOM   10502 C CB  . ILE C 1 426 ? 133.612 140.915 109.278 1.00 24.60 ? 405  ILE C CB  1 
ATOM   10503 C CG1 . ILE C 1 426 ? 134.604 140.710 110.423 1.00 24.60 ? 405  ILE C CG1 1 
ATOM   10504 C CG2 . ILE C 1 426 ? 134.003 142.140 108.483 1.00 24.60 ? 405  ILE C CG2 1 
ATOM   10505 C CD1 . ILE C 1 426 ? 135.018 139.271 110.626 1.00 24.60 ? 405  ILE C CD1 1 
ATOM   10506 N N   . PHE C 1 427 ? 130.658 140.055 108.136 1.00 24.09 ? 406  PHE C N   1 
ATOM   10507 C CA  . PHE C 1 427 ? 129.976 140.019 106.839 1.00 24.09 ? 406  PHE C CA  1 
ATOM   10508 C C   . PHE C 1 427 ? 130.894 140.513 105.722 1.00 24.09 ? 406  PHE C C   1 
ATOM   10509 O O   . PHE C 1 427 ? 130.521 141.357 104.906 1.00 24.09 ? 406  PHE C O   1 
ATOM   10510 C CB  . PHE C 1 427 ? 128.669 140.816 106.847 1.00 24.09 ? 406  PHE C CB  1 
ATOM   10511 C CG  . PHE C 1 427 ? 127.593 140.236 107.708 1.00 24.09 ? 406  PHE C CG  1 
ATOM   10512 C CD1 . PHE C 1 427 ? 126.817 139.186 107.245 1.00 24.09 ? 406  PHE C CD1 1 
ATOM   10513 C CD2 . PHE C 1 427 ? 127.333 140.752 108.965 1.00 24.09 ? 406  PHE C CD2 1 
ATOM   10514 C CE1 . PHE C 1 427 ? 125.811 138.654 108.024 1.00 24.09 ? 406  PHE C CE1 1 
ATOM   10515 C CE2 . PHE C 1 427 ? 126.329 140.226 109.746 1.00 24.09 ? 406  PHE C CE2 1 
ATOM   10516 C CZ  . PHE C 1 427 ? 125.567 139.174 109.275 1.00 24.09 ? 406  PHE C CZ  1 
ATOM   10517 N N   . GLY C 1 428 ? 132.104 139.974 105.683 1.00 17.15 ? 407  GLY C N   1 
ATOM   10518 C CA  . GLY C 1 428 ? 133.051 140.350 104.666 1.00 17.15 ? 407  GLY C CA  1 
ATOM   10519 C C   . GLY C 1 428 ? 134.070 139.264 104.413 1.00 17.15 ? 407  GLY C C   1 
ATOM   10520 O O   . GLY C 1 428 ? 134.182 138.297 105.169 1.00 17.15 ? 407  GLY C O   1 
ATOM   10521 N N   . PRO C 1 429 ? 134.837 139.404 103.343 1.00 15.49 ? 408  PRO C N   1 
ATOM   10522 C CA  . PRO C 1 429 ? 135.879 138.413 103.056 1.00 15.49 ? 408  PRO C CA  1 
ATOM   10523 C C   . PRO C 1 429 ? 137.060 138.532 104.005 1.00 15.49 ? 408  PRO C C   1 
ATOM   10524 O O   . PRO C 1 429 ? 138.175 138.851 103.584 1.00 15.49 ? 408  PRO C O   1 
ATOM   10525 C CB  . PRO C 1 429 ? 136.278 138.738 101.613 1.00 15.49 ? 408  PRO C CB  1 
ATOM   10526 C CG  . PRO C 1 429 ? 135.971 140.179 101.465 1.00 15.49 ? 408  PRO C CG  1 
ATOM   10527 C CD  . PRO C 1 429 ? 134.766 140.450 102.312 1.00 15.49 ? 408  PRO C CD  1 
ATOM   10528 N N   . VAL C 1 430 ? 136.828 138.275 105.288 1.00 17.72 ? 409  VAL C N   1 
ATOM   10529 C CA  . VAL C 1 430 ? 137.854 138.382 106.318 1.00 17.72 ? 409  VAL C CA  1 
ATOM   10530 C C   . VAL C 1 430 ? 137.813 137.104 107.141 1.00 17.72 ? 409  VAL C C   1 
ATOM   10531 O O   . VAL C 1 430 ? 136.820 136.838 107.831 1.00 17.72 ? 409  VAL C O   1 
ATOM   10532 C CB  . VAL C 1 430 ? 137.655 139.614 107.209 1.00 17.72 ? 409  VAL C CB  1 
ATOM   10533 C CG1 . VAL C 1 430 ? 138.529 139.524 108.448 1.00 17.72 ? 409  VAL C CG1 1 
ATOM   10534 C CG2 . VAL C 1 430 ? 137.956 140.878 106.428 1.00 17.72 ? 409  VAL C CG2 1 
ATOM   10535 N N   . VAL C 1 431 ? 138.886 136.320 107.083 1.00 16.84 ? 410  VAL C N   1 
ATOM   10536 C CA  . VAL C 1 431 ? 138.972 135.045 107.782 1.00 16.84 ? 410  VAL C CA  1 
ATOM   10537 C C   . VAL C 1 431 ? 139.999 135.168 108.900 1.00 16.84 ? 410  VAL C C   1 
ATOM   10538 O O   . VAL C 1 431 ? 141.034 135.823 108.738 1.00 16.84 ? 410  VAL C O   1 
ATOM   10539 C CB  . VAL C 1 431 ? 139.320 133.893 106.817 1.00 16.84 ? 410  VAL C CB  1 
ATOM   10540 C CG1 . VAL C 1 431 ? 140.705 134.065 106.228 1.00 16.84 ? 410  VAL C CG1 1 
ATOM   10541 C CG2 . VAL C 1 431 ? 139.188 132.564 107.517 1.00 16.84 ? 410  VAL C CG2 1 
ATOM   10542 N N   . SER C 1 432 ? 139.702 134.549 110.038 1.00 15.08 ? 411  SER C N   1 
ATOM   10543 C CA  . SER C 1 432 ? 140.503 134.663 111.254 1.00 15.08 ? 411  SER C CA  1 
ATOM   10544 C C   . SER C 1 432 ? 141.111 133.300 111.575 1.00 15.08 ? 411  SER C C   1 
ATOM   10545 O O   . SER C 1 432 ? 140.517 132.494 112.293 1.00 15.08 ? 411  SER C O   1 
ATOM   10546 C CB  . SER C 1 432 ? 139.648 135.177 112.401 1.00 15.08 ? 411  SER C CB  1 
ATOM   10547 O OG  . SER C 1 432 ? 138.839 136.257 111.979 1.00 15.08 ? 411  SER C OG  1 
ATOM   10548 N N   . VAL C 1 433 ? 142.307 133.050 111.044 1.00 12.14 ? 412  VAL C N   1 
ATOM   10549 C CA  . VAL C 1 433 ? 142.982 131.780 111.265 1.00 12.14 ? 412  VAL C CA  1 
ATOM   10550 C C   . VAL C 1 433 ? 143.457 131.686 112.712 1.00 12.14 ? 412  VAL C C   1 
ATOM   10551 O O   . VAL C 1 433 ? 143.718 132.697 113.372 1.00 12.14 ? 412  VAL C O   1 
ATOM   10552 C CB  . VAL C 1 433 ? 144.152 131.640 110.274 1.00 12.14 ? 412  VAL C CB  1 
ATOM   10553 C CG1 . VAL C 1 433 ? 144.771 130.264 110.345 1.00 12.14 ? 412  VAL C CG1 1 
ATOM   10554 C CG2 . VAL C 1 433 ? 143.684 131.936 108.865 1.00 12.14 ? 412  VAL C CG2 1 
ATOM   10555 N N   . THR C 1 434 ? 143.555 130.459 113.216 1.00 11.30 ? 413  THR C N   1 
ATOM   10556 C CA  . THR C 1 434 ? 144.076 130.185 114.553 1.00 11.30 ? 413  THR C CA  1 
ATOM   10557 C C   . THR C 1 434 ? 144.621 128.759 114.551 1.00 11.30 ? 413  THR C C   1 
ATOM   10558 O O   . THR C 1 434 ? 144.700 128.115 113.500 1.00 11.30 ? 413  THR C O   1 
ATOM   10559 C CB  . THR C 1 434 ? 142.998 130.413 115.622 1.00 11.30 ? 413  THR C CB  1 
ATOM   10560 O OG1 . THR C 1 434 ? 143.578 130.305 116.926 1.00 11.30 ? 413  THR C OG1 1 
ATOM   10561 C CG2 . THR C 1 434 ? 141.887 129.397 115.493 1.00 11.30 ? 413  THR C CG2 1 
ATOM   10562 N N   . THR C 1 435 ? 145.018 128.262 115.723 1.00 10.82 ? 414  THR C N   1 
ATOM   10563 C CA  . THR C 1 435 ? 145.557 126.912 115.838 1.00 10.82 ? 414  THR C CA  1 
ATOM   10564 C C   . THR C 1 435 ? 145.025 126.241 117.096 1.00 10.82 ? 414  THR C C   1 
ATOM   10565 O O   . THR C 1 435 ? 144.511 126.889 118.011 1.00 10.82 ? 414  THR C O   1 
ATOM   10566 C CB  . THR C 1 435 ? 147.092 126.889 115.866 1.00 10.82 ? 414  THR C CB  1 
ATOM   10567 O OG1 . THR C 1 435 ? 147.566 127.642 116.990 1.00 10.82 ? 414  THR C OG1 1 
ATOM   10568 C CG2 . THR C 1 435 ? 147.681 127.445 114.577 1.00 10.82 ? 414  THR C CG2 1 
ATOM   10569 N N   . PHE C 1 436 ? 145.166 124.917 117.126 1.00 10.78 ? 415  PHE C N   1 
ATOM   10570 C CA  . PHE C 1 436 ? 144.721 124.092 118.239 1.00 10.78 ? 415  PHE C CA  1 
ATOM   10571 C C   . PHE C 1 436 ? 145.649 122.893 118.347 1.00 10.78 ? 415  PHE C C   1 
ATOM   10572 O O   . PHE C 1 436 ? 146.398 122.580 117.420 1.00 10.78 ? 415  PHE C O   1 
ATOM   10573 C CB  . PHE C 1 436 ? 143.267 123.639 118.061 1.00 10.78 ? 415  PHE C CB  1 
ATOM   10574 C CG  . PHE C 1 436 ? 143.054 122.738 116.881 1.00 10.78 ? 415  PHE C CG  1 
ATOM   10575 C CD1 . PHE C 1 436 ? 142.772 123.264 115.640 1.00 10.78 ? 415  PHE C CD1 1 
ATOM   10576 C CD2 . PHE C 1 436 ? 143.138 121.367 117.014 1.00 10.78 ? 415  PHE C CD2 1 
ATOM   10577 C CE1 . PHE C 1 436 ? 142.576 122.440 114.560 1.00 10.78 ? 415  PHE C CE1 1 
ATOM   10578 C CE2 . PHE C 1 436 ? 142.947 120.545 115.935 1.00 10.78 ? 415  PHE C CE2 1 
ATOM   10579 C CZ  . PHE C 1 436 ? 142.663 121.081 114.708 1.00 10.78 ? 415  PHE C CZ  1 
ATOM   10580 N N   . LYS C 1 437 ? 145.587 122.212 119.491 1.00 15.25 ? 416  LYS C N   1 
ATOM   10581 C CA  . LYS C 1 437 ? 146.548 121.150 119.765 1.00 15.25 ? 416  LYS C CA  1 
ATOM   10582 C C   . LYS C 1 437 ? 146.011 119.763 119.419 1.00 15.25 ? 416  LYS C C   1 
ATOM   10583 O O   . LYS C 1 437 ? 146.680 118.999 118.717 1.00 15.25 ? 416  LYS C O   1 
ATOM   10584 C CB  . LYS C 1 437 ? 146.977 121.198 121.234 1.00 15.25 ? 416  LYS C CB  1 
ATOM   10585 C CG  . LYS C 1 437 ? 148.060 120.192 121.589 1.00 15.25 ? 416  LYS C CG  1 
ATOM   10586 C CD  . LYS C 1 437 ? 148.071 119.882 123.077 1.00 15.25 ? 416  LYS C CD  1 
ATOM   10587 C CE  . LYS C 1 437 ? 148.343 118.407 123.338 1.00 15.25 ? 416  LYS C CE  1 
ATOM   10588 N NZ  . LYS C 1 437 ? 147.235 117.530 122.869 1.00 15.25 ? 416  LYS C NZ  1 
ATOM   10589 N N   . ASP C 1 438 ? 144.818 119.420 119.899 1.00 15.85 ? 417  ASP C N   1 
ATOM   10590 C CA  . ASP C 1 438 ? 144.262 118.087 119.698 1.00 15.85 ? 417  ASP C CA  1 
ATOM   10591 C C   . ASP C 1 438 ? 142.779 118.212 119.359 1.00 15.85 ? 417  ASP C C   1 
ATOM   10592 O O   . ASP C 1 438 ? 142.260 119.310 119.139 1.00 15.85 ? 417  ASP C O   1 
ATOM   10593 C CB  . ASP C 1 438 ? 144.506 117.215 120.936 1.00 15.85 ? 417  ASP C CB  1 
ATOM   10594 C CG  . ASP C 1 438 ? 143.579 117.559 122.083 1.00 15.85 ? 417  ASP C CG  1 
ATOM   10595 O OD1 . ASP C 1 438 ? 143.149 118.724 122.170 1.00 15.85 ? 417  ASP C OD1 1 
ATOM   10596 O OD2 . ASP C 1 438 ? 143.279 116.663 122.900 1.00 15.85 ? 417  ASP C OD2 1 
ATOM   10597 N N   . GLN C 1 439 ? 142.092 117.068 119.314 1.00 13.45 ? 418  GLN C N   1 
ATOM   10598 C CA  . GLN C 1 439 ? 140.659 117.072 119.039 1.00 13.45 ? 418  GLN C CA  1 
ATOM   10599 C C   . GLN C 1 439 ? 139.874 117.719 120.174 1.00 13.45 ? 418  GLN C C   1 
ATOM   10600 O O   . GLN C 1 439 ? 138.914 118.460 119.928 1.00 13.45 ? 418  GLN C O   1 
ATOM   10601 C CB  . GLN C 1 439 ? 140.166 115.648 118.794 1.00 13.45 ? 418  GLN C CB  1 
ATOM   10602 C CG  . GLN C 1 439 ? 138.653 115.522 118.744 1.00 13.45 ? 418  GLN C CG  1 
ATOM   10603 C CD  . GLN C 1 439 ? 138.200 114.185 118.199 1.00 13.45 ? 418  GLN C CD  1 
ATOM   10604 O OE1 . GLN C 1 439 ? 138.761 113.675 117.229 1.00 13.45 ? 418  GLN C OE1 1 
ATOM   10605 N NE2 . GLN C 1 439 ? 137.170 113.616 118.812 1.00 13.45 ? 418  GLN C NE2 1 
ATOM   10606 N N   . ALA C 1 440 ? 140.256 117.447 121.421 1.00 15.04 ? 419  ALA C N   1 
ATOM   10607 C CA  . ALA C 1 440 ? 139.531 118.029 122.544 1.00 15.04 ? 419  ALA C CA  1 
ATOM   10608 C C   . ALA C 1 440 ? 139.678 119.544 122.570 1.00 15.04 ? 419  ALA C C   1 
ATOM   10609 O O   . ALA C 1 440 ? 138.713 120.262 122.854 1.00 15.04 ? 419  ALA C O   1 
ATOM   10610 C CB  . ALA C 1 440 ? 140.012 117.417 123.859 1.00 15.04 ? 419  ALA C CB  1 
ATOM   10611 N N   . GLU C 1 441 ? 140.872 120.052 122.261 1.00 15.88 ? 420  GLU C N   1 
ATOM   10612 C CA  . GLU C 1 441 ? 141.057 121.497 122.202 1.00 15.88 ? 420  GLU C CA  1 
ATOM   10613 C C   . GLU C 1 441 ? 140.333 122.094 121.004 1.00 15.88 ? 420  GLU C C   1 
ATOM   10614 O O   . GLU C 1 441 ? 139.818 123.216 121.077 1.00 15.88 ? 420  GLU C O   1 
ATOM   10615 C CB  . GLU C 1 441 ? 142.545 121.836 122.157 1.00 15.88 ? 420  GLU C CB  1 
ATOM   10616 C CG  . GLU C 1 441 ? 142.840 123.325 122.150 1.00 15.88 ? 420  GLU C CG  1 
ATOM   10617 C CD  . GLU C 1 441 ? 142.262 124.038 123.355 1.00 15.88 ? 420  GLU C CD  1 
ATOM   10618 O OE1 . GLU C 1 441 ? 142.131 123.400 124.421 1.00 15.88 ? 420  GLU C OE1 1 
ATOM   10619 O OE2 . GLU C 1 441 ? 141.940 125.238 123.236 1.00 15.88 ? 420  GLU C OE2 1 
ATOM   10620 N N   . ALA C 1 442 ? 140.284 121.362 119.891 1.00 11.88 ? 421  ALA C N   1 
ATOM   10621 C CA  . ALA C 1 442 ? 139.513 121.825 118.744 1.00 11.88 ? 421  ALA C CA  1 
ATOM   10622 C C   . ALA C 1 442 ? 138.045 121.978 119.105 1.00 11.88 ? 421  ALA C C   1 
ATOM   10623 O O   . ALA C 1 442 ? 137.406 122.964 118.727 1.00 11.88 ? 421  ALA C O   1 
ATOM   10624 C CB  . ALA C 1 442 ? 139.678 120.861 117.573 1.00 11.88 ? 421  ALA C CB  1 
ATOM   10625 N N   . LEU C 1 443 ? 137.493 121.014 119.842 1.00 11.99 ? 422  LEU C N   1 
ATOM   10626 C CA  . LEU C 1 443 ? 136.111 121.141 120.286 1.00 11.99 ? 422  LEU C CA  1 
ATOM   10627 C C   . LEU C 1 443 ? 135.946 122.251 121.310 1.00 11.99 ? 422  LEU C C   1 
ATOM   10628 O O   . LEU C 1 443 ? 134.909 122.919 121.330 1.00 11.99 ? 422  LEU C O   1 
ATOM   10629 C CB  . LEU C 1 443 ? 135.611 119.815 120.856 1.00 11.99 ? 422  LEU C CB  1 
ATOM   10630 C CG  . LEU C 1 443 ? 134.954 118.893 119.830 1.00 11.99 ? 422  LEU C CG  1 
ATOM   10631 C CD1 . LEU C 1 443 ? 134.637 117.536 120.424 1.00 11.99 ? 422  LEU C CD1 1 
ATOM   10632 C CD2 . LEU C 1 443 ? 133.697 119.549 119.296 1.00 11.99 ? 422  LEU C CD2 1 
ATOM   10633 N N   . GLU C 1 444 ? 136.942 122.454 122.173 1.00 15.84 ? 423  GLU C N   1 
ATOM   10634 C CA  . GLU C 1 444 ? 136.842 123.510 123.175 1.00 15.84 ? 423  GLU C CA  1 
ATOM   10635 C C   . GLU C 1 444 ? 136.852 124.892 122.538 1.00 15.84 ? 423  GLU C C   1 
ATOM   10636 O O   . GLU C 1 444 ? 136.180 125.805 123.029 1.00 15.84 ? 423  GLU C O   1 
ATOM   10637 C CB  . GLU C 1 444 ? 137.984 123.383 124.181 1.00 15.84 ? 423  GLU C CB  1 
ATOM   10638 C CG  . GLU C 1 444 ? 137.833 124.252 125.422 1.00 15.84 ? 423  GLU C CG  1 
ATOM   10639 C CD  . GLU C 1 444 ? 137.008 123.590 126.510 1.00 15.84 ? 423  GLU C CD  1 
ATOM   10640 O OE1 . GLU C 1 444 ? 137.271 123.859 127.700 1.00 15.84 ? 423  GLU C OE1 1 
ATOM   10641 O OE2 . GLU C 1 444 ? 136.096 122.803 126.180 1.00 15.84 ? 423  GLU C OE2 1 
ATOM   10642 N N   . ILE C 1 445 ? 137.603 125.061 121.452 1.00 14.07 ? 424  ILE C N   1 
ATOM   10643 C CA  . ILE C 1 445 ? 137.682 126.357 120.787 1.00 14.07 ? 424  ILE C CA  1 
ATOM   10644 C C   . ILE C 1 445 ? 136.496 126.561 119.854 1.00 14.07 ? 424  ILE C C   1 
ATOM   10645 O O   . ILE C 1 445 ? 135.841 127.608 119.880 1.00 14.07 ? 424  ILE C O   1 
ATOM   10646 C CB  . ILE C 1 445 ? 139.016 126.485 120.035 1.00 14.07 ? 424  ILE C CB  1 
ATOM   10647 C CG1 . ILE C 1 445 ? 140.141 126.837 121.001 1.00 14.07 ? 424  ILE C CG1 1 
ATOM   10648 C CG2 . ILE C 1 445 ? 138.914 127.538 118.963 1.00 14.07 ? 424  ILE C CG2 1 
ATOM   10649 C CD1 . ILE C 1 445 ? 141.504 126.798 120.369 1.00 14.07 ? 424  ILE C CD1 1 
ATOM   10650 N N   . ALA C 1 446 ? 136.196 125.561 119.020 1.00 13.93 ? 425  ALA C N   1 
ATOM   10651 C CA  . ALA C 1 446 ? 135.110 125.675 118.054 1.00 13.93 ? 425  ALA C CA  1 
ATOM   10652 C C   . ALA C 1 446 ? 133.762 125.918 118.715 1.00 13.93 ? 425  ALA C C   1 
ATOM   10653 O O   . ALA C 1 446 ? 132.854 126.446 118.067 1.00 13.93 ? 425  ALA C O   1 
ATOM   10654 C CB  . ALA C 1 446 ? 135.044 124.415 117.193 1.00 13.93 ? 425  ALA C CB  1 
ATOM   10655 N N   . ASN C 1 447 ? 133.605 125.543 119.978 1.00 14.58 ? 426  ASN C N   1 
ATOM   10656 C CA  . ASN C 1 447 ? 132.388 125.819 120.723 1.00 14.58 ? 426  ASN C CA  1 
ATOM   10657 C C   . ASN C 1 447 ? 132.476 127.102 121.533 1.00 14.58 ? 426  ASN C C   1 
ATOM   10658 O O   . ASN C 1 447 ? 131.567 127.388 122.318 1.00 14.58 ? 426  ASN C O   1 
ATOM   10659 C CB  . ASN C 1 447 ? 132.058 124.650 121.648 1.00 14.58 ? 426  ASN C CB  1 
ATOM   10660 C CG  . ASN C 1 447 ? 131.449 123.483 120.913 1.00 14.58 ? 426  ASN C CG  1 
ATOM   10661 O OD1 . ASN C 1 447 ? 130.415 123.617 120.265 1.00 14.58 ? 426  ASN C OD1 1 
ATOM   10662 N ND2 . ASN C 1 447 ? 132.086 122.326 121.012 1.00 14.58 ? 426  ASN C ND2 1 
ATOM   10663 N N   . ASP C 1 448 ? 133.551 127.873 121.372 1.00 21.90 ? 427  ASP C N   1 
ATOM   10664 C CA  . ASP C 1 448 ? 133.708 129.147 122.073 1.00 21.90 ? 427  ASP C CA  1 
ATOM   10665 C C   . ASP C 1 448 ? 133.177 130.253 121.173 1.00 21.90 ? 427  ASP C C   1 
ATOM   10666 O O   . ASP C 1 448 ? 133.906 130.834 120.369 1.00 21.90 ? 427  ASP C O   1 
ATOM   10667 C CB  . ASP C 1 448 ? 135.165 129.383 122.449 1.00 21.90 ? 427  ASP C CB  1 
ATOM   10668 C CG  . ASP C 1 448 ? 135.318 130.368 123.585 1.00 21.90 ? 427  ASP C CG  1 
ATOM   10669 O OD1 . ASP C 1 448 ? 134.484 130.340 124.514 1.00 21.90 ? 427  ASP C OD1 1 
ATOM   10670 O OD2 . ASP C 1 448 ? 136.272 131.170 123.547 1.00 21.90 ? 427  ASP C OD2 1 
ATOM   10671 N N   . THR C 1 449 ? 131.889 130.547 121.318 1.00 26.38 ? 428  THR C N   1 
ATOM   10672 C CA  . THR C 1 449 ? 131.210 131.574 120.538 1.00 26.38 ? 428  THR C CA  1 
ATOM   10673 C C   . THR C 1 449 ? 129.786 131.688 121.067 1.00 26.38 ? 428  THR C C   1 
ATOM   10674 O O   . THR C 1 449 ? 129.279 130.787 121.741 1.00 26.38 ? 428  THR C O   1 
ATOM   10675 C CB  . THR C 1 449 ? 131.202 131.259 119.040 1.00 26.38 ? 428  THR C CB  1 
ATOM   10676 O OG1 . THR C 1 449 ? 130.522 132.303 118.336 1.00 26.38 ? 428  THR C OG1 1 
ATOM   10677 C CG2 . THR C 1 449 ? 130.506 129.933 118.776 1.00 26.38 ? 428  THR C CG2 1 
ATOM   10678 N N   . LEU C 1 450 ? 129.146 132.813 120.753 1.00 30.79 ? 429  LEU C N   1 
ATOM   10679 C CA  . LEU C 1 450 ? 127.737 133.047 121.065 1.00 30.79 ? 429  LEU C CA  1 
ATOM   10680 C C   . LEU C 1 450 ? 126.860 132.695 119.874 1.00 30.79 ? 429  LEU C C   1 
ATOM   10681 O O   . LEU C 1 450 ? 125.822 133.315 119.629 1.00 30.79 ? 429  LEU C O   1 
ATOM   10682 C CB  . LEU C 1 450 ? 127.512 134.498 121.488 1.00 30.79 ? 429  LEU C CB  1 
ATOM   10683 C CG  . LEU C 1 450 ? 127.907 134.938 122.905 1.00 30.79 ? 429  LEU C CG  1 
ATOM   10684 C CD1 . LEU C 1 450 ? 129.420 135.010 123.083 1.00 30.79 ? 429  LEU C CD1 1 
ATOM   10685 C CD2 . LEU C 1 450 ? 127.259 136.266 123.268 1.00 30.79 ? 429  LEU C CD2 1 
ATOM   10686 N N   . TYR C 1 451 ? 127.271 131.682 119.122 1.00 29.01 ? 430  TYR C N   1 
ATOM   10687 C CA  . TYR C 1 451 ? 126.767 131.422 117.784 1.00 29.01 ? 430  TYR C CA  1 
ATOM   10688 C C   . TYR C 1 451 ? 126.805 129.910 117.575 1.00 29.01 ? 430  TYR C C   1 
ATOM   10689 O O   . TYR C 1 451 ? 126.796 129.144 118.545 1.00 29.01 ? 430  TYR C O   1 
ATOM   10690 C CB  . TYR C 1 451 ? 127.582 132.212 116.749 1.00 29.01 ? 430  TYR C CB  1 
ATOM   10691 C CG  . TYR C 1 451 ? 127.332 133.703 116.808 1.00 29.01 ? 430  TYR C CG  1 
ATOM   10692 C CD1 . TYR C 1 451 ? 126.059 134.225 116.623 1.00 29.01 ? 430  TYR C CD1 1 
ATOM   10693 C CD2 . TYR C 1 451 ? 128.372 134.588 117.056 1.00 29.01 ? 430  TYR C CD2 1 
ATOM   10694 C CE1 . TYR C 1 451 ? 125.830 135.586 116.679 1.00 29.01 ? 430  TYR C CE1 1 
ATOM   10695 C CE2 . TYR C 1 451 ? 128.153 135.949 117.115 1.00 29.01 ? 430  TYR C CE2 1 
ATOM   10696 C CZ  . TYR C 1 451 ? 126.881 136.444 116.927 1.00 29.01 ? 430  TYR C CZ  1 
ATOM   10697 O OH  . TYR C 1 451 ? 126.665 137.802 116.985 1.00 29.01 ? 430  TYR C OH  1 
ATOM   10698 N N   . GLY C 1 452 ? 126.836 129.475 116.320 1.00 17.19 ? 431  GLY C N   1 
ATOM   10699 C CA  . GLY C 1 452 ? 126.673 128.062 116.049 1.00 17.19 ? 431  GLY C CA  1 
ATOM   10700 C C   . GLY C 1 452 ? 125.786 127.776 114.860 1.00 17.19 ? 431  GLY C C   1 
ATOM   10701 O O   . GLY C 1 452 ? 125.296 126.660 114.692 1.00 17.19 ? 431  GLY C O   1 
ATOM   10702 N N   . LEU C 1 453 ? 125.547 128.793 114.037 1.00 16.77 ? 432  LEU C N   1 
ATOM   10703 C CA  . LEU C 1 453 ? 124.736 128.595 112.844 1.00 16.77 ? 432  LEU C CA  1 
ATOM   10704 C C   . LEU C 1 453 ? 125.336 127.543 111.913 1.00 16.77 ? 432  LEU C C   1 
ATOM   10705 O O   . LEU C 1 453 ? 124.618 126.970 111.087 1.00 16.77 ? 432  LEU C O   1 
ATOM   10706 C CB  . LEU C 1 453 ? 124.565 129.924 112.112 1.00 16.77 ? 432  LEU C CB  1 
ATOM   10707 C CG  . LEU C 1 453 ? 123.276 130.058 111.309 1.00 16.77 ? 432  LEU C CG  1 
ATOM   10708 C CD1 . LEU C 1 453 ? 122.099 130.233 112.250 1.00 16.77 ? 432  LEU C CD1 1 
ATOM   10709 C CD2 . LEU C 1 453 ? 123.374 131.230 110.370 1.00 16.77 ? 432  LEU C CD2 1 
ATOM   10710 N N   . GLY C 1 454 ? 126.631 127.273 112.024 1.00 9.92  ? 433  GLY C N   1 
ATOM   10711 C CA  . GLY C 1 454 ? 127.247 126.257 111.188 1.00 9.92  ? 433  GLY C CA  1 
ATOM   10712 C C   . GLY C 1 454 ? 128.650 125.950 111.658 1.00 9.92  ? 433  GLY C C   1 
ATOM   10713 O O   . GLY C 1 454 ? 129.199 126.627 112.530 1.00 9.92  ? 433  GLY C O   1 
ATOM   10714 N N   . ALA C 1 455 ? 129.221 124.904 111.070 1.00 5.60  ? 434  ALA C N   1 
ATOM   10715 C CA  . ALA C 1 455 ? 130.585 124.502 111.377 1.00 5.60  ? 434  ALA C CA  1 
ATOM   10716 C C   . ALA C 1 455 ? 131.095 123.621 110.252 1.00 5.60  ? 434  ALA C C   1 
ATOM   10717 O O   . ALA C 1 455 ? 130.317 123.070 109.476 1.00 5.60  ? 434  ALA C O   1 
ATOM   10718 C CB  . ALA C 1 455 ? 130.669 123.769 112.716 1.00 5.60  ? 434  ALA C CB  1 
ATOM   10719 N N   . GLY C 1 456 ? 132.412 123.486 110.176 1.00 10.72 ? 435  GLY C N   1 
ATOM   10720 C CA  . GLY C 1 456 ? 133.014 122.662 109.148 1.00 10.72 ? 435  GLY C CA  1 
ATOM   10721 C C   . GLY C 1 456 ? 134.203 121.880 109.654 1.00 10.72 ? 435  GLY C C   1 
ATOM   10722 O O   . GLY C 1 456 ? 135.113 122.456 110.251 1.00 10.72 ? 435  GLY C O   1 
ATOM   10723 N N   . VAL C 1 457 ? 134.213 120.570 109.432 1.00 3.99  ? 436  VAL C N   1 
ATOM   10724 C CA  . VAL C 1 457 ? 135.253 119.683 109.937 1.00 3.99  ? 436  VAL C CA  1 
ATOM   10725 C C   . VAL C 1 457 ? 135.907 118.993 108.754 1.00 3.99  ? 436  VAL C C   1 
ATOM   10726 O O   . VAL C 1 457 ? 135.216 118.427 107.903 1.00 3.99  ? 436  VAL C O   1 
ATOM   10727 C CB  . VAL C 1 457 ? 134.685 118.645 110.920 1.00 3.99  ? 436  VAL C CB  1 
ATOM   10728 C CG1 . VAL C 1 457 ? 135.805 117.864 111.562 1.00 3.99  ? 436  VAL C CG1 1 
ATOM   10729 C CG2 . VAL C 1 457 ? 133.829 119.318 111.967 1.00 3.99  ? 436  VAL C CG2 1 
ATOM   10730 N N   . TRP C 1 458 ? 137.233 119.041 108.697 1.00 5.26  ? 437  TRP C N   1 
ATOM   10731 C CA  . TRP C 1 458 ? 137.997 118.379 107.648 1.00 5.26  ? 437  TRP C CA  1 
ATOM   10732 C C   . TRP C 1 458 ? 138.948 117.389 108.298 1.00 5.26  ? 437  TRP C C   1 
ATOM   10733 O O   . TRP C 1 458 ? 139.777 117.777 109.126 1.00 5.26  ? 437  TRP C O   1 
ATOM   10734 C CB  . TRP C 1 458 ? 138.763 119.391 106.797 1.00 5.26  ? 437  TRP C CB  1 
ATOM   10735 C CG  . TRP C 1 458 ? 137.878 120.323 106.051 1.00 5.26  ? 437  TRP C CG  1 
ATOM   10736 C CD1 . TRP C 1 458 ? 137.170 121.363 106.568 1.00 5.26  ? 437  TRP C CD1 1 
ATOM   10737 C CD2 . TRP C 1 458 ? 137.592 120.298 104.652 1.00 5.26  ? 437  TRP C CD2 1 
ATOM   10738 N NE1 . TRP C 1 458 ? 136.465 121.993 105.577 1.00 5.26  ? 437  TRP C NE1 1 
ATOM   10739 C CE2 . TRP C 1 458 ? 136.706 121.355 104.390 1.00 5.26  ? 437  TRP C CE2 1 
ATOM   10740 C CE3 . TRP C 1 458 ? 137.999 119.483 103.595 1.00 5.26  ? 437  TRP C CE3 1 
ATOM   10741 C CZ2 . TRP C 1 458 ? 136.223 121.620 103.118 1.00 5.26  ? 437  TRP C CZ2 1 
ATOM   10742 C CZ3 . TRP C 1 458 ? 137.519 119.749 102.332 1.00 5.26  ? 437  TRP C CZ3 1 
ATOM   10743 C CH2 . TRP C 1 458 ? 136.642 120.808 102.104 1.00 5.26  ? 437  TRP C CH2 1 
ATOM   10744 N N   . SER C 1 459 ? 138.835 116.121 107.913 1.00 6.20  ? 438  SER C N   1 
ATOM   10745 C CA  . SER C 1 459 ? 139.620 115.052 108.510 1.00 6.20  ? 438  SER C CA  1 
ATOM   10746 C C   . SER C 1 459 ? 139.464 113.801 107.667 1.00 6.20  ? 438  SER C C   1 
ATOM   10747 O O   . SER C 1 459 ? 138.428 113.596 107.031 1.00 6.20  ? 438  SER C O   1 
ATOM   10748 C CB  . SER C 1 459 ? 139.183 114.769 109.949 1.00 6.20  ? 438  SER C CB  1 
ATOM   10749 O OG  . SER C 1 459 ? 140.065 113.856 110.573 1.00 6.20  ? 438  SER C OG  1 
ATOM   10750 N N   . ARG C 1 460 ? 140.500 112.966 107.673 1.00 8.04  ? 439  ARG C N   1 
ATOM   10751 C CA  . ARG C 1 460 ? 140.481 111.694 106.969 1.00 8.04  ? 439  ARG C CA  1 
ATOM   10752 C C   . ARG C 1 460 ? 140.204 110.520 107.897 1.00 8.04  ? 439  ARG C C   1 
ATOM   10753 O O   . ARG C 1 460 ? 140.540 109.382 107.558 1.00 8.04  ? 439  ARG C O   1 
ATOM   10754 C CB  . ARG C 1 460 ? 141.803 111.467 106.243 1.00 8.04  ? 439  ARG C CB  1 
ATOM   10755 C CG  . ARG C 1 460 ? 142.335 112.646 105.473 1.00 8.04  ? 439  ARG C CG  1 
ATOM   10756 C CD  . ARG C 1 460 ? 143.515 112.206 104.625 1.00 8.04  ? 439  ARG C CD  1 
ATOM   10757 N NE  . ARG C 1 460 ? 143.891 113.198 103.628 1.00 8.04  ? 439  ARG C NE  1 
ATOM   10758 C CZ  . ARG C 1 460 ? 144.611 112.927 102.545 1.00 8.04  ? 439  ARG C CZ  1 
ATOM   10759 N NH1 . ARG C 1 460 ? 145.029 111.690 102.321 1.00 8.04  ? 439  ARG C NH1 1 
ATOM   10760 N NH2 . ARG C 1 460 ? 144.911 113.888 101.686 1.00 8.04  ? 439  ARG C NH2 1 
ATOM   10761 N N   . ASP C 1 461 ? 139.605 110.765 109.057 1.00 7.03  ? 440  ASP C N   1 
ATOM   10762 C CA  . ASP C 1 461 ? 139.379 109.725 110.048 1.00 7.03  ? 440  ASP C CA  1 
ATOM   10763 C C   . ASP C 1 461 ? 137.897 109.651 110.373 1.00 7.03  ? 440  ASP C C   1 
ATOM   10764 O O   . ASP C 1 461 ? 137.250 110.679 110.581 1.00 7.03  ? 440  ASP C O   1 
ATOM   10765 C CB  . ASP C 1 461 ? 140.190 109.996 111.315 1.00 7.03  ? 440  ASP C CB  1 
ATOM   10766 C CG  . ASP C 1 461 ? 140.147 108.848 112.292 1.00 7.03  ? 440  ASP C CG  1 
ATOM   10767 O OD1 . ASP C 1 461 ? 140.813 107.828 112.030 1.00 7.03  ? 440  ASP C OD1 1 
ATOM   10768 O OD2 . ASP C 1 461 ? 139.459 108.965 113.324 1.00 7.03  ? 440  ASP C OD2 1 
ATOM   10769 N N   . ALA C 1 462 ? 137.362 108.430 110.415 1.00 6.03  ? 441  ALA C N   1 
ATOM   10770 C CA  . ALA C 1 462 ? 135.926 108.253 110.613 1.00 6.03  ? 441  ALA C CA  1 
ATOM   10771 C C   . ALA C 1 462 ? 135.503 108.674 112.012 1.00 6.03  ? 441  ALA C C   1 
ATOM   10772 O O   . ALA C 1 462 ? 134.500 109.376 112.184 1.00 6.03  ? 441  ALA C O   1 
ATOM   10773 C CB  . ALA C 1 462 ? 135.535 106.800 110.350 1.00 6.03  ? 441  ALA C CB  1 
ATOM   10774 N N   . ASN C 1 463 ? 136.253 108.248 113.027 1.00 5.92  ? 442  ASN C N   1 
ATOM   10775 C CA  . ASN C 1 463 ? 135.909 108.597 114.400 1.00 5.92  ? 442  ASN C CA  1 
ATOM   10776 C C   . ASN C 1 463 ? 136.024 110.094 114.633 1.00 5.92  ? 442  ASN C C   1 
ATOM   10777 O O   . ASN C 1 463 ? 135.191 110.691 115.328 1.00 5.92  ? 442  ASN C O   1 
ATOM   10778 C CB  . ASN C 1 463 ? 136.810 107.838 115.368 1.00 5.92  ? 442  ASN C CB  1 
ATOM   10779 C CG  . ASN C 1 463 ? 136.200 106.543 115.827 1.00 5.92  ? 442  ASN C CG  1 
ATOM   10780 O OD1 . ASN C 1 463 ? 135.243 106.541 116.595 1.00 5.92  ? 442  ASN C OD1 1 
ATOM   10781 N ND2 . ASN C 1 463 ? 136.744 105.428 115.354 1.00 5.92  ? 442  ASN C ND2 1 
ATOM   10782 N N   . THR C 1 464 ? 137.057 110.716 114.064 1.00 5.40  ? 443  THR C N   1 
ATOM   10783 C CA  . THR C 1 464 ? 137.237 112.153 114.217 1.00 5.40  ? 443  THR C CA  1 
ATOM   10784 C C   . THR C 1 464 ? 136.045 112.913 113.660 1.00 5.40  ? 443  THR C C   1 
ATOM   10785 O O   . THR C 1 464 ? 135.478 113.777 114.336 1.00 5.40  ? 443  THR C O   1 
ATOM   10786 C CB  . THR C 1 464 ? 138.524 112.597 113.523 1.00 5.40  ? 443  THR C CB  1 
ATOM   10787 O OG1 . THR C 1 464 ? 139.654 112.045 114.205 1.00 5.40  ? 443  THR C OG1 1 
ATOM   10788 C CG2 . THR C 1 464 ? 138.628 114.104 113.526 1.00 5.40  ? 443  THR C CG2 1 
ATOM   10789 N N   . CYS C 1 465 ? 135.644 112.594 112.428 1.00 4.95  ? 444  CYS C N   1 
ATOM   10790 C CA  . CYS C 1 465 ? 134.571 113.339 111.779 1.00 4.95  ? 444  CYS C CA  1 
ATOM   10791 C C   . CYS C 1 465 ? 133.262 113.205 112.544 1.00 4.95  ? 444  CYS C C   1 
ATOM   10792 O O   . CYS C 1 465 ? 132.575 114.199 112.800 1.00 4.95  ? 444  CYS C O   1 
ATOM   10793 C CB  . CYS C 1 465 ? 134.403 112.860 110.339 1.00 4.95  ? 444  CYS C CB  1 
ATOM   10794 S SG  . CYS C 1 465 ? 135.773 113.271 109.244 1.00 4.95  ? 444  CYS C SG  1 
ATOM   10795 N N   . TYR C 1 466 ? 132.901 111.980 112.925 1.00 3.35  ? 445  TYR C N   1 
ATOM   10796 C CA  . TYR C 1 466 ? 131.642 111.785 113.631 1.00 3.35  ? 445  TYR C CA  1 
ATOM   10797 C C   . TYR C 1 466 ? 131.667 112.443 114.999 1.00 3.35  ? 445  TYR C C   1 
ATOM   10798 O O   . TYR C 1 466 ? 130.692 113.087 115.397 1.00 3.35  ? 445  TYR C O   1 
ATOM   10799 C CB  . TYR C 1 466 ? 131.329 110.297 113.767 1.00 3.35  ? 445  TYR C CB  1 
ATOM   10800 C CG  . TYR C 1 466 ? 130.095 110.020 114.595 1.00 3.35  ? 445  TYR C CG  1 
ATOM   10801 C CD1 . TYR C 1 466 ? 128.835 110.034 114.022 1.00 3.35  ? 445  TYR C CD1 1 
ATOM   10802 C CD2 . TYR C 1 466 ? 130.192 109.744 115.948 1.00 3.35  ? 445  TYR C CD2 1 
ATOM   10803 C CE1 . TYR C 1 466 ? 127.713 109.783 114.772 1.00 3.35  ? 445  TYR C CE1 1 
ATOM   10804 C CE2 . TYR C 1 466 ? 129.077 109.498 116.704 1.00 3.35  ? 445  TYR C CE2 1 
ATOM   10805 C CZ  . TYR C 1 466 ? 127.841 109.516 116.113 1.00 3.35  ? 445  TYR C CZ  1 
ATOM   10806 O OH  . TYR C 1 466 ? 126.726 109.268 116.876 1.00 3.35  ? 445  TYR C OH  1 
ATOM   10807 N N   . ARG C 1 467 ? 132.764 112.290 115.740 1.00 4.85  ? 446  ARG C N   1 
ATOM   10808 C CA  . ARG C 1 467 ? 132.814 112.863 117.080 1.00 4.85  ? 446  ARG C CA  1 
ATOM   10809 C C   . ARG C 1 467 ? 132.810 114.382 117.030 1.00 4.85  ? 446  ARG C C   1 
ATOM   10810 O O   . ARG C 1 467 ? 132.174 115.032 117.865 1.00 4.85  ? 446  ARG C O   1 
ATOM   10811 C CB  . ARG C 1 467 ? 134.035 112.343 117.824 1.00 4.85  ? 446  ARG C CB  1 
ATOM   10812 C CG  . ARG C 1 467 ? 133.887 110.903 118.250 1.00 4.85  ? 446  ARG C CG  1 
ATOM   10813 C CD  . ARG C 1 467 ? 132.916 110.795 119.407 1.00 4.85  ? 446  ARG C CD  1 
ATOM   10814 N NE  . ARG C 1 467 ? 132.622 109.410 119.747 1.00 4.85  ? 446  ARG C NE  1 
ATOM   10815 C CZ  . ARG C 1 467 ? 131.440 108.992 120.176 1.00 4.85  ? 446  ARG C CZ  1 
ATOM   10816 N NH1 . ARG C 1 467 ? 130.447 109.855 120.315 1.00 4.85  ? 446  ARG C NH1 1 
ATOM   10817 N NH2 . ARG C 1 467 ? 131.253 107.716 120.465 1.00 4.85  ? 446  ARG C NH2 1 
ATOM   10818 N N   . MET C 1 468 ? 133.500 114.968 116.051 1.00 5.55  ? 447  MET C N   1 
ATOM   10819 C CA  . MET C 1 468 ? 133.451 116.412 115.868 1.00 5.55  ? 447  MET C CA  1 
ATOM   10820 C C   . MET C 1 468 ? 132.044 116.871 115.518 1.00 5.55  ? 447  MET C C   1 
ATOM   10821 O O   . MET C 1 468 ? 131.498 117.775 116.157 1.00 5.55  ? 447  MET C O   1 
ATOM   10822 C CB  . MET C 1 468 ? 134.438 116.830 114.781 1.00 5.55  ? 447  MET C CB  1 
ATOM   10823 C CG  . MET C 1 468 ? 135.889 116.766 115.201 1.00 5.55  ? 447  MET C CG  1 
ATOM   10824 S SD  . MET C 1 468 ? 136.193 117.501 116.813 1.00 5.55  ? 447  MET C SD  1 
ATOM   10825 C CE  . MET C 1 468 ? 136.188 119.237 116.393 1.00 5.55  ? 447  MET C CE  1 
ATOM   10826 N N   . GLY C 1 469 ? 131.434 116.249 114.507 1.00 3.87  ? 448  GLY C N   1 
ATOM   10827 C CA  . GLY C 1 469 ? 130.108 116.665 114.091 1.00 3.87  ? 448  GLY C CA  1 
ATOM   10828 C C   . GLY C 1 469 ? 129.079 116.543 115.195 1.00 3.87  ? 448  GLY C C   1 
ATOM   10829 O O   . GLY C 1 469 ? 128.191 117.387 115.324 1.00 3.87  ? 448  GLY C O   1 
ATOM   10830 N N   . ARG C 1 470 ? 129.183 115.497 116.009 1.00 3.44  ? 449  ARG C N   1 
ATOM   10831 C CA  . ARG C 1 470 ? 128.213 115.308 117.076 1.00 3.44  ? 449  ARG C CA  1 
ATOM   10832 C C   . ARG C 1 470 ? 128.543 116.120 118.319 1.00 3.44  ? 449  ARG C C   1 
ATOM   10833 O O   . ARG C 1 470 ? 127.648 116.374 119.129 1.00 3.44  ? 449  ARG C O   1 
ATOM   10834 C CB  . ARG C 1 470 ? 128.113 113.823 117.420 1.00 3.44  ? 449  ARG C CB  1 
ATOM   10835 C CG  . ARG C 1 470 ? 127.718 112.964 116.232 1.00 3.44  ? 449  ARG C CG  1 
ATOM   10836 C CD  . ARG C 1 470 ? 126.270 113.167 115.858 1.00 3.44  ? 449  ARG C CD  1 
ATOM   10837 N NE  . ARG C 1 470 ? 125.399 112.230 116.554 1.00 3.44  ? 449  ARG C NE  1 
ATOM   10838 C CZ  . ARG C 1 470 ? 124.463 112.596 117.418 1.00 3.44  ? 449  ARG C CZ  1 
ATOM   10839 N NH1 . ARG C 1 470 ? 124.299 113.873 117.698 1.00 3.44  ? 449  ARG C NH1 1 
ATOM   10840 N NH2 . ARG C 1 470 ? 123.708 111.690 118.012 1.00 3.44  ? 449  ARG C NH2 1 
ATOM   10841 N N   . GLY C 1 471 ? 129.795 116.542 118.482 1.00 5.15  ? 450  GLY C N   1 
ATOM   10842 C CA  . GLY C 1 471 ? 130.191 117.323 119.634 1.00 5.15  ? 450  GLY C CA  1 
ATOM   10843 C C   . GLY C 1 471 ? 130.041 118.813 119.425 1.00 5.15  ? 450  GLY C C   1 
ATOM   10844 O O   . GLY C 1 471 ? 129.621 119.528 120.338 1.00 5.15  ? 450  GLY C O   1 
ATOM   10845 N N   . ILE C 1 472 ? 130.395 119.290 118.228 1.00 5.24  ? 451  ILE C N   1 
ATOM   10846 C CA  . ILE C 1 472 ? 130.211 120.695 117.888 1.00 5.24  ? 451  ILE C CA  1 
ATOM   10847 C C   . ILE C 1 472 ? 128.762 121.083 118.100 1.00 5.24  ? 451  ILE C C   1 
ATOM   10848 O O   . ILE C 1 472 ? 127.846 120.381 117.664 1.00 5.24  ? 451  ILE C O   1 
ATOM   10849 C CB  . ILE C 1 472 ? 130.651 120.959 116.439 1.00 5.24  ? 451  ILE C CB  1 
ATOM   10850 C CG1 . ILE C 1 472 ? 132.167 120.902 116.319 1.00 5.24  ? 451  ILE C CG1 1 
ATOM   10851 C CG2 . ILE C 1 472 ? 130.162 122.297 115.974 1.00 5.24  ? 451  ILE C CG2 1 
ATOM   10852 C CD1 . ILE C 1 472 ? 132.650 120.918 114.911 1.00 5.24  ? 451  ILE C CD1 1 
ATOM   10853 N N   . LYS C 1 473 ? 128.546 122.216 118.764 1.00 7.33  ? 452  LYS C N   1 
ATOM   10854 C CA  . LYS C 1 473 ? 127.202 122.690 119.063 1.00 7.33  ? 452  LYS C CA  1 
ATOM   10855 C C   . LYS C 1 473 ? 126.628 123.553 117.952 1.00 7.33  ? 452  LYS C C   1 
ATOM   10856 O O   . LYS C 1 473 ? 125.797 124.430 118.213 1.00 7.33  ? 452  LYS C O   1 
ATOM   10857 C CB  . LYS C 1 473 ? 127.188 123.446 120.389 1.00 7.33  ? 452  LYS C CB  1 
ATOM   10858 C CG  . LYS C 1 473 ? 126.764 122.585 121.554 1.00 7.33  ? 452  LYS C CG  1 
ATOM   10859 C CD  . LYS C 1 473 ? 125.385 121.991 121.313 1.00 7.33  ? 452  LYS C CD  1 
ATOM   10860 C CE  . LYS C 1 473 ? 124.330 123.073 121.141 1.00 7.33  ? 452  LYS C CE  1 
ATOM   10861 N NZ  . LYS C 1 473 ? 122.950 122.530 121.251 1.00 7.33  ? 452  LYS C NZ  1 
ATOM   10862 N N   . ALA C 1 474 ? 127.043 123.318 116.714 1.00 7.00  ? 453  ALA C N   1 
ATOM   10863 C CA  . ALA C 1 474 ? 126.451 123.990 115.571 1.00 7.00  ? 453  ALA C CA  1 
ATOM   10864 C C   . ALA C 1 474 ? 125.118 123.320 115.251 1.00 7.00  ? 453  ALA C C   1 
ATOM   10865 O O   . ALA C 1 474 ? 124.593 122.523 116.031 1.00 7.00  ? 453  ALA C O   1 
ATOM   10866 C CB  . ALA C 1 474 ? 127.410 123.969 114.388 1.00 7.00  ? 453  ALA C CB  1 
ATOM   10867 N N   . GLY C 1 475 ? 124.535 123.658 114.108 1.00 4.94  ? 454  GLY C N   1 
ATOM   10868 C CA  . GLY C 1 475 ? 123.293 123.034 113.703 1.00 4.94  ? 454  GLY C CA  1 
ATOM   10869 C C   . GLY C 1 475 ? 123.424 122.329 112.375 1.00 4.94  ? 454  GLY C C   1 
ATOM   10870 O O   . GLY C 1 475 ? 122.661 121.410 112.071 1.00 4.94  ? 454  GLY C O   1 
ATOM   10871 N N   . ARG C 1 476 ? 124.394 122.754 111.572 1.00 5.29  ? 455  ARG C N   1 
ATOM   10872 C CA  . ARG C 1 476 ? 124.664 122.141 110.274 1.00 5.29  ? 455  ARG C CA  1 
ATOM   10873 C C   . ARG C 1 476 ? 126.175 122.002 110.158 1.00 5.29  ? 455  ARG C C   1 
ATOM   10874 O O   . ARG C 1 476 ? 126.869 122.973 109.852 1.00 5.29  ? 455  ARG C O   1 
ATOM   10875 C CB  . ARG C 1 476 ? 124.095 122.968 109.130 1.00 5.29  ? 455  ARG C CB  1 
ATOM   10876 C CG  . ARG C 1 476 ? 124.172 122.282 107.788 1.00 5.29  ? 455  ARG C CG  1 
ATOM   10877 C CD  . ARG C 1 476 ? 123.199 122.901 106.811 1.00 5.29  ? 455  ARG C CD  1 
ATOM   10878 N NE  . ARG C 1 476 ? 122.759 121.945 105.799 1.00 5.29  ? 455  ARG C NE  1 
ATOM   10879 C CZ  . ARG C 1 476 ? 122.920 122.101 104.489 1.00 5.29  ? 455  ARG C CZ  1 
ATOM   10880 N NH1 . ARG C 1 476 ? 123.512 123.181 104.006 1.00 5.29  ? 455  ARG C NH1 1 
ATOM   10881 N NH2 . ARG C 1 476 ? 122.482 121.171 103.659 1.00 5.29  ? 455  ARG C NH2 1 
ATOM   10882 N N   . VAL C 1 477 ? 126.676 120.801 110.397 1.00 3.10  ? 456  VAL C N   1 
ATOM   10883 C CA  . VAL C 1 477 ? 128.105 120.534 110.390 1.00 3.10  ? 456  VAL C CA  1 
ATOM   10884 C C   . VAL C 1 477 ? 128.457 119.948 109.036 1.00 3.10  ? 456  VAL C C   1 
ATOM   10885 O O   . VAL C 1 477 ? 127.952 118.890 108.659 1.00 3.10  ? 456  VAL C O   1 
ATOM   10886 C CB  . VAL C 1 477 ? 128.507 119.592 111.530 1.00 3.10  ? 456  VAL C CB  1 
ATOM   10887 C CG1 . VAL C 1 477 ? 130.009 119.549 111.671 1.00 3.10  ? 456  VAL C CG1 1 
ATOM   10888 C CG2 . VAL C 1 477 ? 127.867 120.042 112.828 1.00 3.10  ? 456  VAL C CG2 1 
ATOM   10889 N N   . TRP C 1 478 ? 129.308 120.640 108.294 1.00 4.73  ? 457  TRP C N   1 
ATOM   10890 C CA  . TRP C 1 478 ? 129.853 120.090 107.068 1.00 4.73  ? 457  TRP C CA  1 
ATOM   10891 C C   . TRP C 1 478 ? 131.054 119.214 107.387 1.00 4.73  ? 457  TRP C C   1 
ATOM   10892 O O   . TRP C 1 478 ? 131.776 119.449 108.355 1.00 4.73  ? 457  TRP C O   1 
ATOM   10893 C CB  . TRP C 1 478 ? 130.266 121.209 106.120 1.00 4.73  ? 457  TRP C CB  1 
ATOM   10894 C CG  . TRP C 1 478 ? 129.132 121.878 105.438 1.00 4.73  ? 457  TRP C CG  1 
ATOM   10895 C CD1 . TRP C 1 478 ? 128.612 121.562 104.224 1.00 4.73  ? 457  TRP C CD1 1 
ATOM   10896 C CD2 . TRP C 1 478 ? 128.373 122.987 105.923 1.00 4.73  ? 457  TRP C CD2 1 
ATOM   10897 N NE1 . TRP C 1 478 ? 127.574 122.401 103.921 1.00 4.73  ? 457  TRP C NE1 1 
ATOM   10898 C CE2 . TRP C 1 478 ? 127.406 123.287 104.951 1.00 4.73  ? 457  TRP C CE2 1 
ATOM   10899 C CE3 . TRP C 1 478 ? 128.415 123.753 107.089 1.00 4.73  ? 457  TRP C CE3 1 
ATOM   10900 C CZ2 . TRP C 1 478 ? 126.491 124.320 105.106 1.00 4.73  ? 457  TRP C CZ2 1 
ATOM   10901 C CZ3 . TRP C 1 478 ? 127.506 124.776 107.241 1.00 4.73  ? 457  TRP C CZ3 1 
ATOM   10902 C CH2 . TRP C 1 478 ? 126.556 125.051 106.255 1.00 4.73  ? 457  TRP C CH2 1 
ATOM   10903 N N   . THR C 1 479 ? 131.274 118.199 106.558 1.00 2.59  ? 458  THR C N   1 
ATOM   10904 C CA  . THR C 1 479 ? 132.382 117.274 106.744 1.00 2.59  ? 458  THR C CA  1 
ATOM   10905 C C   . THR C 1 479 ? 133.040 117.025 105.400 1.00 2.59  ? 458  THR C C   1 
ATOM   10906 O O   . THR C 1 479 ? 132.406 116.482 104.493 1.00 2.59  ? 458  THR C O   1 
ATOM   10907 C CB  . THR C 1 479 ? 131.910 115.956 107.355 1.00 2.59  ? 458  THR C CB  1 
ATOM   10908 O OG1 . THR C 1 479 ? 131.315 116.201 108.635 1.00 2.59  ? 458  THR C OG1 1 
ATOM   10909 C CG2 . THR C 1 479 ? 133.075 115.016 107.526 1.00 2.59  ? 458  THR C CG2 1 
ATOM   10910 N N   . ASN C 1 480 ? 134.308 117.420 105.278 1.00 2.91  ? 459  ASN C N   1 
ATOM   10911 C CA  . ASN C 1 480 ? 135.086 117.264 104.046 1.00 2.91  ? 459  ASN C CA  1 
ATOM   10912 C C   . ASN C 1 480 ? 134.407 117.944 102.860 1.00 2.91  ? 459  ASN C C   1 
ATOM   10913 O O   . ASN C 1 480 ? 134.508 117.498 101.718 1.00 2.91  ? 459  ASN C O   1 
ATOM   10914 C CB  . ASN C 1 480 ? 135.364 115.793 103.748 1.00 2.91  ? 459  ASN C CB  1 
ATOM   10915 C CG  . ASN C 1 480 ? 136.185 115.133 104.828 1.00 2.91  ? 459  ASN C CG  1 
ATOM   10916 O OD1 . ASN C 1 480 ? 136.267 115.630 105.948 1.00 2.91  ? 459  ASN C OD1 1 
ATOM   10917 N ND2 . ASN C 1 480 ? 136.791 114.003 104.501 1.00 2.91  ? 459  ASN C ND2 1 
ATOM   10918 N N   . CYS C 1 481 ? 133.724 119.044 103.143 1.00 4.33  ? 460  CYS C N   1 
ATOM   10919 C CA  . CYS C 1 481 ? 133.103 119.917 102.156 1.00 4.33  ? 460  CYS C CA  1 
ATOM   10920 C C   . CYS C 1 481 ? 132.664 121.158 102.911 1.00 4.33  ? 460  CYS C C   1 
ATOM   10921 O O   . CYS C 1 481 ? 132.702 121.195 104.142 1.00 4.33  ? 460  CYS C O   1 
ATOM   10922 C CB  . CYS C 1 481 ? 131.910 119.261 101.462 1.00 4.33  ? 460  CYS C CB  1 
ATOM   10923 S SG  . CYS C 1 481 ? 130.442 119.081 102.517 1.00 4.33  ? 460  CYS C SG  1 
ATOM   10924 N N   . TYR C 1 482 ? 132.247 122.177 102.171 1.00 7.01  ? 461  TYR C N   1 
ATOM   10925 C CA  . TYR C 1 482 ? 131.595 123.286 102.846 1.00 7.01  ? 461  TYR C CA  1 
ATOM   10926 C C   . TYR C 1 482 ? 130.727 124.003 101.827 1.00 7.01  ? 461  TYR C C   1 
ATOM   10927 O O   . TYR C 1 482 ? 130.915 123.861 100.617 1.00 7.01  ? 461  TYR C O   1 
ATOM   10928 C CB  . TYR C 1 482 ? 132.604 124.255 103.475 1.00 7.01  ? 461  TYR C CB  1 
ATOM   10929 C CG  . TYR C 1 482 ? 132.016 125.044 104.617 1.00 7.01  ? 461  TYR C CG  1 
ATOM   10930 C CD1 . TYR C 1 482 ? 132.004 124.514 105.895 1.00 7.01  ? 461  TYR C CD1 1 
ATOM   10931 C CD2 . TYR C 1 482 ? 131.410 126.271 104.418 1.00 7.01  ? 461  TYR C CD2 1 
ATOM   10932 C CE1 . TYR C 1 482 ? 131.458 125.203 106.951 1.00 7.01  ? 461  TYR C CE1 1 
ATOM   10933 C CE2 . TYR C 1 482 ? 130.843 126.959 105.469 1.00 7.01  ? 461  TYR C CE2 1 
ATOM   10934 C CZ  . TYR C 1 482 ? 130.875 126.419 106.732 1.00 7.01  ? 461  TYR C CZ  1 
ATOM   10935 O OH  . TYR C 1 482 ? 130.324 127.097 107.787 1.00 7.01  ? 461  TYR C OH  1 
ATOM   10936 N N   . HIS C 1 483 ? 129.758 124.759 102.338 1.00 11.00 ? 462  HIS C N   1 
ATOM   10937 C CA  . HIS C 1 483 ? 128.910 125.647 101.545 1.00 11.00 ? 462  HIS C CA  1 
ATOM   10938 C C   . HIS C 1 483 ? 128.092 124.910 100.498 1.00 11.00 ? 462  HIS C C   1 
ATOM   10939 O O   . HIS C 1 483 ? 127.596 125.525 99.550  1.00 11.00 ? 462  HIS C O   1 
ATOM   10940 C CB  . HIS C 1 483 ? 129.726 126.758 100.878 1.00 11.00 ? 462  HIS C CB  1 
ATOM   10941 C CG  . HIS C 1 483 ? 129.900 127.967 101.738 1.00 11.00 ? 462  HIS C CG  1 
ATOM   10942 N ND1 . HIS C 1 483 ? 128.869 128.506 102.476 1.00 11.00 ? 462  HIS C ND1 1 
ATOM   10943 C CD2 . HIS C 1 483 ? 130.980 128.746 101.974 1.00 11.00 ? 462  HIS C CD2 1 
ATOM   10944 C CE1 . HIS C 1 483 ? 129.308 129.563 103.135 1.00 11.00 ? 462  HIS C CE1 1 
ATOM   10945 N NE2 . HIS C 1 483 ? 130.585 129.732 102.845 1.00 11.00 ? 462  HIS C NE2 1 
ATOM   10946 N N   . ALA C 1 484 ? 127.939 123.600 100.644 1.00 8.63  ? 463  ALA C N   1 
ATOM   10947 C CA  . ALA C 1 484 ? 126.981 122.858 99.839  1.00 8.63  ? 463  ALA C CA  1 
ATOM   10948 C C   . ALA C 1 484 ? 125.615 123.005 100.496 1.00 8.63  ? 463  ALA C C   1 
ATOM   10949 O O   . ALA C 1 484 ? 125.400 122.515 101.608 1.00 8.63  ? 463  ALA C O   1 
ATOM   10950 C CB  . ALA C 1 484 ? 127.394 121.396 99.720  1.00 8.63  ? 463  ALA C CB  1 
ATOM   10951 N N   . TYR C 1 485 ? 124.698 123.702 99.824  1.00 9.88  ? 464  TYR C N   1 
ATOM   10952 C CA  . TYR C 1 485 ? 123.345 123.935 100.324 1.00 9.88  ? 464  TYR C CA  1 
ATOM   10953 C C   . TYR C 1 485 ? 122.351 123.279 99.375  1.00 9.88  ? 464  TYR C C   1 
ATOM   10954 O O   . TYR C 1 485 ? 121.682 123.960 98.587  1.00 9.88  ? 464  TYR C O   1 
ATOM   10955 C CB  . TYR C 1 485 ? 123.042 125.425 100.468 1.00 9.88  ? 464  TYR C CB  1 
ATOM   10956 C CG  . TYR C 1 485 ? 123.958 126.146 101.421 1.00 9.88  ? 464  TYR C CG  1 
ATOM   10957 C CD1 . TYR C 1 485 ? 125.139 126.714 100.977 1.00 9.88  ? 464  TYR C CD1 1 
ATOM   10958 C CD2 . TYR C 1 485 ? 123.641 126.261 102.769 1.00 9.88  ? 464  TYR C CD2 1 
ATOM   10959 C CE1 . TYR C 1 485 ? 125.979 127.371 101.837 1.00 9.88  ? 464  TYR C CE1 1 
ATOM   10960 C CE2 . TYR C 1 485 ? 124.477 126.920 103.642 1.00 9.88  ? 464  TYR C CE2 1 
ATOM   10961 C CZ  . TYR C 1 485 ? 125.650 127.470 103.169 1.00 9.88  ? 464  TYR C CZ  1 
ATOM   10962 O OH  . TYR C 1 485 ? 126.499 128.132 104.028 1.00 9.88  ? 464  TYR C OH  1 
ATOM   10963 N N   . PRO C 1 486 ? 122.228 121.959 99.422  1.00 8.06  ? 465  PRO C N   1 
ATOM   10964 C CA  . PRO C 1 486 ? 121.271 121.279 98.555  1.00 8.06  ? 465  PRO C CA  1 
ATOM   10965 C C   . PRO C 1 486 ? 119.909 121.153 99.219  1.00 8.06  ? 465  PRO C C   1 
ATOM   10966 O O   . PRO C 1 486 ? 119.768 121.190 100.443 1.00 8.06  ? 465  PRO C O   1 
ATOM   10967 C CB  . PRO C 1 486 ? 121.918 119.905 98.355  1.00 8.06  ? 465  PRO C CB  1 
ATOM   10968 C CG  . PRO C 1 486 ? 122.670 119.668 99.631  1.00 8.06  ? 465  PRO C CG  1 
ATOM   10969 C CD  . PRO C 1 486 ? 122.967 121.003 100.265 1.00 8.06  ? 465  PRO C CD  1 
ATOM   10970 N N   . ALA C 1 487 ? 118.896 121.018 98.374  1.00 7.22  ? 466  ALA C N   1 
ATOM   10971 C CA  . ALA C 1 487 ? 117.553 120.786 98.869  1.00 7.22  ? 466  ALA C CA  1 
ATOM   10972 C C   . ALA C 1 487 ? 117.451 119.391 99.471  1.00 7.22  ? 466  ALA C C   1 
ATOM   10973 O O   . ALA C 1 487 ? 118.210 118.483 99.124  1.00 7.22  ? 466  ALA C O   1 
ATOM   10974 C CB  . ALA C 1 487 ? 116.532 120.962 97.747  1.00 7.22  ? 466  ALA C CB  1 
ATOM   10975 N N   . HIS C 1 488 ? 116.508 119.242 100.395 1.00 4.40  ? 467  HIS C N   1 
ATOM   10976 C CA  . HIS C 1 488 ? 116.127 118.031 101.120 1.00 4.40  ? 467  HIS C CA  1 
ATOM   10977 C C   . HIS C 1 488 ? 117.118 117.775 102.249 1.00 4.40  ? 467  HIS C C   1 
ATOM   10978 O O   . HIS C 1 488 ? 116.917 116.848 103.040 1.00 4.40  ? 467  HIS C O   1 
ATOM   10979 C CB  . HIS C 1 488 ? 116.002 116.809 100.188 1.00 4.40  ? 467  HIS C CB  1 
ATOM   10980 C CG  . HIS C 1 488 ? 115.550 115.553 100.862 1.00 4.40  ? 467  HIS C CG  1 
ATOM   10981 N ND1 . HIS C 1 488 ? 114.249 115.371 101.278 1.00 4.40  ? 467  HIS C ND1 1 
ATOM   10982 C CD2 . HIS C 1 488 ? 116.176 114.375 101.071 1.00 4.40  ? 467  HIS C CD2 1 
ATOM   10983 C CE1 . HIS C 1 488 ? 114.118 114.166 101.799 1.00 4.40  ? 467  HIS C CE1 1 
ATOM   10984 N NE2 . HIS C 1 488 ? 115.273 113.539 101.681 1.00 4.40  ? 467  HIS C NE2 1 
ATOM   10985 N N   . ALA C 1 489 ? 118.148 118.603 102.385 1.00 6.70  ? 468  ALA C N   1 
ATOM   10986 C CA  . ALA C 1 489 ? 119.068 118.561 103.515 1.00 6.70  ? 468  ALA C CA  1 
ATOM   10987 C C   . ALA C 1 489 ? 118.817 119.794 104.372 1.00 6.70  ? 468  ALA C C   1 
ATOM   10988 O O   . ALA C 1 489 ? 118.922 120.925 103.887 1.00 6.70  ? 468  ALA C O   1 
ATOM   10989 C CB  . ALA C 1 489 ? 120.515 118.516 103.033 1.00 6.70  ? 468  ALA C CB  1 
ATOM   10990 N N   . ALA C 1 490 ? 118.487 119.580 105.640 1.00 6.68  ? 469  ALA C N   1 
ATOM   10991 C CA  . ALA C 1 490 ? 118.242 120.687 106.562 1.00 6.68  ? 469  ALA C CA  1 
ATOM   10992 C C   . ALA C 1 490 ? 119.550 121.351 106.978 1.00 6.68  ? 469  ALA C C   1 
ATOM   10993 O O   . ALA C 1 490 ? 120.325 121.801 106.135 1.00 6.68  ? 469  ALA C O   1 
ATOM   10994 C CB  . ALA C 1 490 ? 117.484 120.205 107.783 1.00 6.68  ? 469  ALA C CB  1 
ATOM   10995 N N   . THR C 1 503 ? 114.930 124.418 103.394 1.00 8.52  ? 482  THR C N   1 
ATOM   10996 C CA  . THR C 1 503 ? 115.772 123.568 102.561 1.00 8.52  ? 482  THR C CA  1 
ATOM   10997 C C   . THR C 1 503 ? 115.357 122.105 102.665 1.00 8.52  ? 482  THR C C   1 
ATOM   10998 O O   . THR C 1 503 ? 115.497 121.340 101.713 1.00 8.52  ? 482  THR C O   1 
ATOM   10999 C CB  . THR C 1 503 ? 117.251 123.706 102.939 1.00 8.52  ? 482  THR C CB  1 
ATOM   11000 O OG1 . THR C 1 503 ? 117.439 123.290 104.296 1.00 8.52  ? 482  THR C OG1 1 
ATOM   11001 C CG2 . THR C 1 503 ? 117.702 125.147 102.790 1.00 8.52  ? 482  THR C CG2 1 
ATOM   11002 N N   . HIS C 1 504 ? 114.841 121.725 103.826 1.00 8.33  ? 483  HIS C N   1 
ATOM   11003 C CA  . HIS C 1 504 ? 114.408 120.359 104.060 1.00 8.33  ? 483  HIS C CA  1 
ATOM   11004 C C   . HIS C 1 504 ? 112.893 120.262 103.910 1.00 8.33  ? 483  HIS C C   1 
ATOM   11005 O O   . HIS C 1 504 ? 112.171 121.256 103.981 1.00 8.33  ? 483  HIS C O   1 
ATOM   11006 C CB  . HIS C 1 504 ? 114.859 119.897 105.447 1.00 8.33  ? 483  HIS C CB  1 
ATOM   11007 C CG  . HIS C 1 504 ? 114.531 118.469 105.752 1.00 8.33  ? 483  HIS C CG  1 
ATOM   11008 N ND1 . HIS C 1 504 ? 115.201 117.415 105.171 1.00 8.33  ? 483  HIS C ND1 1 
ATOM   11009 C CD2 . HIS C 1 504 ? 113.622 117.921 106.591 1.00 8.33  ? 483  HIS C CD2 1 
ATOM   11010 C CE1 . HIS C 1 504 ? 114.711 116.278 105.631 1.00 8.33  ? 483  HIS C CE1 1 
ATOM   11011 N NE2 . HIS C 1 504 ? 113.751 116.557 106.493 1.00 8.33  ? 483  HIS C NE2 1 
ATOM   11012 N N   . LYS C 1 505 ? 112.410 119.036 103.709 1.00 7.92  ? 484  LYS C N   1 
ATOM   11013 C CA  . LYS C 1 505 ? 110.990 118.806 103.476 1.00 7.92  ? 484  LYS C CA  1 
ATOM   11014 C C   . LYS C 1 505 ? 110.122 119.113 104.690 1.00 7.92  ? 484  LYS C C   1 
ATOM   11015 O O   . LYS C 1 505 ? 108.896 118.999 104.590 1.00 7.92  ? 484  LYS C O   1 
ATOM   11016 C CB  . LYS C 1 505 ? 110.756 117.361 103.039 1.00 7.92  ? 484  LYS C CB  1 
ATOM   11017 C CG  . LYS C 1 505 ? 111.477 116.324 103.871 1.00 7.92  ? 484  LYS C CG  1 
ATOM   11018 C CD  . LYS C 1 505 ? 111.090 114.922 103.446 1.00 7.92  ? 484  LYS C CD  1 
ATOM   11019 C CE  . LYS C 1 505 ? 109.594 114.711 103.574 1.00 7.92  ? 484  LYS C CE  1 
ATOM   11020 N NZ  . LYS C 1 505 ? 109.073 115.180 104.889 1.00 7.92  ? 484  LYS C NZ  1 
ATOM   11021 N N   . MET C 1 506 ? 110.712 119.485 105.823 1.00 13.12 ? 485  MET C N   1 
ATOM   11022 C CA  . MET C 1 506 ? 109.950 119.868 107.002 1.00 13.12 ? 485  MET C CA  1 
ATOM   11023 C C   . MET C 1 506 ? 109.661 121.362 107.044 1.00 13.12 ? 485  MET C C   1 
ATOM   11024 O O   . MET C 1 506 ? 109.057 121.839 108.008 1.00 13.12 ? 485  MET C O   1 
ATOM   11025 C CB  . MET C 1 506 ? 110.681 119.436 108.273 1.00 13.12 ? 485  MET C CB  1 
ATOM   11026 C CG  . MET C 1 506 ? 111.805 120.363 108.695 1.00 13.12 ? 485  MET C CG  1 
ATOM   11027 S SD  . MET C 1 506 ? 112.907 119.600 109.899 1.00 13.12 ? 485  MET C SD  1 
ATOM   11028 C CE  . MET C 1 506 ? 114.407 120.536 109.625 1.00 13.12 ? 485  MET C CE  1 
ATOM   11029 N N   . MET C 1 507 ? 110.078 122.110 106.020 1.00 7.66  ? 486  MET C N   1 
ATOM   11030 C CA  . MET C 1 507 ? 109.675 123.508 105.921 1.00 7.66  ? 486  MET C CA  1 
ATOM   11031 C C   . MET C 1 507 ? 108.200 123.634 105.571 1.00 7.66  ? 486  MET C C   1 
ATOM   11032 O O   . MET C 1 507 ? 107.546 124.600 105.973 1.00 7.66  ? 486  MET C O   1 
ATOM   11033 C CB  . MET C 1 507 ? 110.530 124.240 104.889 1.00 7.66  ? 486  MET C CB  1 
ATOM   11034 C CG  . MET C 1 507 ? 111.932 124.564 105.348 1.00 7.66  ? 486  MET C CG  1 
ATOM   11035 S SD  . MET C 1 507 ? 112.590 125.982 104.455 1.00 7.66  ? 486  MET C SD  1 
ATOM   11036 C CE  . MET C 1 507 ? 112.023 127.315 105.512 1.00 7.66  ? 486  MET C CE  1 
ATOM   11037 N N   . LEU C 1 508 ? 107.659 122.678 104.811 1.00 5.19  ? 487  LEU C N   1 
ATOM   11038 C CA  . LEU C 1 508 ? 106.247 122.731 104.451 1.00 5.19  ? 487  LEU C CA  1 
ATOM   11039 C C   . LEU C 1 508 ? 105.359 122.755 105.683 1.00 5.19  ? 487  LEU C C   1 
ATOM   11040 O O   . LEU C 1 508 ? 104.237 123.265 105.630 1.00 5.19  ? 487  LEU C O   1 
ATOM   11041 C CB  . LEU C 1 508 ? 105.884 121.545 103.560 1.00 5.19  ? 487  LEU C CB  1 
ATOM   11042 C CG  . LEU C 1 508 ? 105.846 121.806 102.056 1.00 5.19  ? 487  LEU C CG  1 
ATOM   11043 C CD1 . LEU C 1 508 ? 105.354 120.592 101.306 1.00 5.19  ? 487  LEU C CD1 1 
ATOM   11044 C CD2 . LEU C 1 508 ? 104.939 122.966 101.789 1.00 5.19  ? 487  LEU C CD2 1 
ATOM   11045 N N   . ASP C 1 509 ? 105.841 122.213 106.798 1.00 6.76  ? 488  ASP C N   1 
ATOM   11046 C CA  . ASP C 1 509 ? 105.088 122.276 108.040 1.00 6.76  ? 488  ASP C CA  1 
ATOM   11047 C C   . ASP C 1 509 ? 105.203 123.633 108.719 1.00 6.76  ? 488  ASP C C   1 
ATOM   11048 O O   . ASP C 1 509 ? 104.400 123.931 109.608 1.00 6.76  ? 488  ASP C O   1 
ATOM   11049 C CB  . ASP C 1 509 ? 105.565 121.179 108.985 1.00 6.76  ? 488  ASP C CB  1 
ATOM   11050 C CG  . ASP C 1 509 ? 105.450 119.803 108.375 1.00 6.76  ? 488  ASP C CG  1 
ATOM   11051 O OD1 . ASP C 1 509 ? 106.195 119.520 107.414 1.00 6.76  ? 488  ASP C OD1 1 
ATOM   11052 O OD2 . ASP C 1 509 ? 104.628 119.001 108.865 1.00 6.76  ? 488  ASP C OD2 1 
ATOM   11053 N N   . HIS C 1 510 ? 106.186 124.454 108.338 1.00 6.46  ? 489  HIS C N   1 
ATOM   11054 C CA  . HIS C 1 510 ? 106.235 125.820 108.849 1.00 6.46  ? 489  HIS C CA  1 
ATOM   11055 C C   . HIS C 1 510 ? 105.019 126.609 108.393 1.00 6.46  ? 489  HIS C C   1 
ATOM   11056 O O   . HIS C 1 510 ? 104.421 127.356 109.174 1.00 6.46  ? 489  HIS C O   1 
ATOM   11057 C CB  . HIS C 1 510 ? 107.508 126.529 108.385 1.00 6.46  ? 489  HIS C CB  1 
ATOM   11058 C CG  . HIS C 1 510 ? 108.769 125.980 108.972 1.00 6.46  ? 489  HIS C CG  1 
ATOM   11059 N ND1 . HIS C 1 510 ? 109.960 126.673 108.947 1.00 6.46  ? 489  HIS C ND1 1 
ATOM   11060 C CD2 . HIS C 1 510 ? 109.031 124.807 109.594 1.00 6.46  ? 489  HIS C CD2 1 
ATOM   11061 C CE1 . HIS C 1 510 ? 110.900 125.951 109.529 1.00 6.46  ? 489  HIS C CE1 1 
ATOM   11062 N NE2 . HIS C 1 510 ? 110.363 124.814 109.931 1.00 6.46  ? 489  HIS C NE2 1 
ATOM   11063 N N   . TYR C 1 511 ? 104.640 126.454 107.128 1.00 3.88  ? 490  TYR C N   1 
ATOM   11064 C CA  . TYR C 1 511 ? 103.541 127.193 106.527 1.00 3.88  ? 490  TYR C CA  1 
ATOM   11065 C C   . TYR C 1 511 ? 102.261 126.374 106.471 1.00 3.88  ? 490  TYR C C   1 
ATOM   11066 O O   . TYR C 1 511 ? 101.448 126.553 105.562 1.00 3.88  ? 490  TYR C O   1 
ATOM   11067 C CB  . TYR C 1 511 ? 103.932 127.659 105.128 1.00 3.88  ? 490  TYR C CB  1 
ATOM   11068 C CG  . TYR C 1 511 ? 105.259 128.368 105.081 1.00 3.88  ? 490  TYR C CG  1 
ATOM   11069 C CD1 . TYR C 1 511 ? 105.356 129.716 105.376 1.00 3.88  ? 490  TYR C CD1 1 
ATOM   11070 C CD2 . TYR C 1 511 ? 106.415 127.689 104.749 1.00 3.88  ? 490  TYR C CD2 1 
ATOM   11071 C CE1 . TYR C 1 511 ? 106.564 130.365 105.335 1.00 3.88  ? 490  TYR C CE1 1 
ATOM   11072 C CE2 . TYR C 1 511 ? 107.627 128.331 104.708 1.00 3.88  ? 490  TYR C CE2 1 
ATOM   11073 C CZ  . TYR C 1 511 ? 107.697 129.667 104.997 1.00 3.88  ? 490  TYR C CZ  1 
ATOM   11074 O OH  . TYR C 1 511 ? 108.913 130.303 104.950 1.00 3.88  ? 490  TYR C OH  1 
ATOM   11075 N N   . GLN C 1 512 ? 102.072 125.473 107.423 1.00 3.01  ? 491  GLN C N   1 
ATOM   11076 C CA  . GLN C 1 512 ? 100.875 124.657 107.485 1.00 3.01  ? 491  GLN C CA  1 
ATOM   11077 C C   . GLN C 1 512 ? 100.410 124.564 108.922 1.00 3.01  ? 491  GLN C C   1 
ATOM   11078 O O   . GLN C 1 512 ? 101.224 124.497 109.844 1.00 3.01  ? 491  GLN C O   1 
ATOM   11079 C CB  . GLN C 1 512 ? 101.111 123.246 106.957 1.00 3.01  ? 491  GLN C CB  1 
ATOM   11080 C CG  . GLN C 1 512 ? 100.892 123.065 105.489 1.00 3.01  ? 491  GLN C CG  1 
ATOM   11081 C CD  . GLN C 1 512 ? 101.382 121.726 105.039 1.00 3.01  ? 491  GLN C CD  1 
ATOM   11082 O OE1 . GLN C 1 512 ? 101.992 121.001 105.813 1.00 3.01  ? 491  GLN C OE1 1 
ATOM   11083 N NE2 . GLN C 1 512 ? 101.126 121.384 103.789 1.00 3.01  ? 491  GLN C NE2 1 
ATOM   11084 N N   . GLN C 1 513 ? 99.103  124.563 109.097 1.00 3.40  ? 492  GLN C N   1 
ATOM   11085 C CA  . GLN C 1 513 ? 98.473  124.184 110.346 1.00 3.40  ? 492  GLN C CA  1 
ATOM   11086 C C   . GLN C 1 513 ? 97.854  122.802 110.183 1.00 3.40  ? 492  GLN C C   1 
ATOM   11087 O O   . GLN C 1 513 ? 97.764  122.263 109.081 1.00 3.40  ? 492  GLN C O   1 
ATOM   11088 C CB  . GLN C 1 513 ? 97.444  125.239 110.749 1.00 3.40  ? 492  GLN C CB  1 
ATOM   11089 C CG  . GLN C 1 513 ? 96.357  125.462 109.727 1.00 3.40  ? 492  GLN C CG  1 
ATOM   11090 C CD  . GLN C 1 513 ? 95.437  126.603 110.104 1.00 3.40  ? 492  GLN C CD  1 
ATOM   11091 O OE1 . GLN C 1 513 ? 95.566  127.190 111.177 1.00 3.40  ? 492  GLN C OE1 1 
ATOM   11092 N NE2 . GLN C 1 513 ? 94.513  126.936 109.214 1.00 3.40  ? 492  GLN C NE2 1 
ATOM   11093 N N   . THR C 1 514 ? 97.461  122.207 111.299 1.00 4.56  ? 493  THR C N   1 
ATOM   11094 C CA  . THR C 1 514 ? 96.937  120.851 111.293 1.00 4.56  ? 493  THR C CA  1 
ATOM   11095 C C   . THR C 1 514 ? 95.488  120.853 111.754 1.00 4.56  ? 493  THR C C   1 
ATOM   11096 O O   . THR C 1 514 ? 95.131  121.541 112.715 1.00 4.56  ? 493  THR C O   1 
ATOM   11097 C CB  . THR C 1 514 ? 97.776  119.931 112.182 1.00 4.56  ? 493  THR C CB  1 
ATOM   11098 O OG1 . THR C 1 514 ? 99.141  119.974 111.751 1.00 4.56  ? 493  THR C OG1 1 
ATOM   11099 C CG2 . THR C 1 514 ? 97.293  118.503 112.076 1.00 4.56  ? 493  THR C CG2 1 
ATOM   11100 N N   . LYS C 1 515 ? 94.656  120.095 111.048 1.00 4.49  ? 494  LYS C N   1 
ATOM   11101 C CA  . LYS C 1 515 ? 93.258  119.903 111.405 1.00 4.49  ? 494  LYS C CA  1 
ATOM   11102 C C   . LYS C 1 515 ? 93.069  118.489 111.936 1.00 4.49  ? 494  LYS C C   1 
ATOM   11103 O O   . LYS C 1 515 ? 93.423  117.520 111.262 1.00 4.49  ? 494  LYS C O   1 
ATOM   11104 C CB  . LYS C 1 515 ? 92.359  120.141 110.194 1.00 4.49  ? 494  LYS C CB  1 
ATOM   11105 C CG  . LYS C 1 515 ? 90.932  119.684 110.379 1.00 4.49  ? 494  LYS C CG  1 
ATOM   11106 C CD  . LYS C 1 515 ? 90.258  120.423 111.509 1.00 4.49  ? 494  LYS C CD  1 
ATOM   11107 C CE  . LYS C 1 515 ? 90.119  121.886 111.176 1.00 4.49  ? 494  LYS C CE  1 
ATOM   11108 N NZ  . LYS C 1 515 ? 89.375  122.069 109.908 1.00 4.49  ? 494  LYS C NZ  1 
ATOM   11109 N N   . ASN C 1 516 ? 92.513  118.371 113.138 1.00 6.73  ? 495  ASN C N   1 
ATOM   11110 C CA  . ASN C 1 516 ? 92.316  117.079 113.782 1.00 6.73  ? 495  ASN C CA  1 
ATOM   11111 C C   . ASN C 1 516 ? 90.826  116.807 113.900 1.00 6.73  ? 495  ASN C C   1 
ATOM   11112 O O   . ASN C 1 516 ? 90.102  117.576 114.537 1.00 6.73  ? 495  ASN C O   1 
ATOM   11113 C CB  . ASN C 1 516 ? 92.968  117.040 115.164 1.00 6.73  ? 495  ASN C CB  1 
ATOM   11114 C CG  . ASN C 1 516 ? 94.422  117.439 115.132 1.00 6.73  ? 495  ASN C CG  1 
ATOM   11115 O OD1 . ASN C 1 516 ? 94.984  117.675 114.070 1.00 6.73  ? 495  ASN C OD1 1 
ATOM   11116 N ND2 . ASN C 1 516 ? 95.041  117.517 116.301 1.00 6.73  ? 495  ASN C ND2 1 
ATOM   11117 N N   . MET C 1 517 ? 90.375  115.711 113.301 1.00 6.32  ? 496  MET C N   1 
ATOM   11118 C CA  . MET C 1 517 ? 88.982  115.293 113.364 1.00 6.32  ? 496  MET C CA  1 
ATOM   11119 C C   . MET C 1 517 ? 88.914  113.934 114.039 1.00 6.32  ? 496  MET C C   1 
ATOM   11120 O O   . MET C 1 517 ? 89.422  112.950 113.501 1.00 6.32  ? 496  MET C O   1 
ATOM   11121 C CB  . MET C 1 517 ? 88.365  115.224 111.969 1.00 6.32  ? 496  MET C CB  1 
ATOM   11122 C CG  . MET C 1 517 ? 88.487  116.498 111.169 1.00 6.32  ? 496  MET C CG  1 
ATOM   11123 S SD  . MET C 1 517 ? 87.627  116.370 109.596 1.00 6.32  ? 496  MET C SD  1 
ATOM   11124 C CE  . MET C 1 517 ? 86.085  115.636 110.131 1.00 6.32  ? 496  MET C CE  1 
ATOM   11125 N N   . LEU C 1 518 ? 88.287  113.875 115.206 1.00 7.03  ? 497  LEU C N   1 
ATOM   11126 C CA  . LEU C 1 518 ? 88.140  112.632 115.951 1.00 7.03  ? 497  LEU C CA  1 
ATOM   11127 C C   . LEU C 1 518 ? 86.699  112.161 115.802 1.00 7.03  ? 497  LEU C C   1 
ATOM   11128 O O   . LEU C 1 518 ? 85.768  112.864 116.204 1.00 7.03  ? 497  LEU C O   1 
ATOM   11129 C CB  . LEU C 1 518 ? 88.523  112.839 117.415 1.00 7.03  ? 497  LEU C CB  1 
ATOM   11130 C CG  . LEU C 1 518 ? 88.758  111.626 118.310 1.00 7.03  ? 497  LEU C CG  1 
ATOM   11131 C CD1 . LEU C 1 518 ? 89.859  111.933 119.298 1.00 7.03  ? 497  LEU C CD1 1 
ATOM   11132 C CD2 . LEU C 1 518 ? 87.499  111.278 119.055 1.00 7.03  ? 497  LEU C CD2 1 
ATOM   11133 N N   . VAL C 1 519 ? 86.521  110.981 115.212 1.00 7.60  ? 498  VAL C N   1 
ATOM   11134 C CA  . VAL C 1 519 ? 85.225  110.499 114.752 1.00 7.60  ? 498  VAL C CA  1 
ATOM   11135 C C   . VAL C 1 519 ? 84.930  109.176 115.441 1.00 7.60  ? 498  VAL C C   1 
ATOM   11136 O O   . VAL C 1 519 ? 85.770  108.272 115.434 1.00 7.60  ? 498  VAL C O   1 
ATOM   11137 C CB  . VAL C 1 519 ? 85.206  110.316 113.225 1.00 7.60  ? 498  VAL C CB  1 
ATOM   11138 C CG1 . VAL C 1 519 ? 83.888  109.725 112.788 1.00 7.60  ? 498  VAL C CG1 1 
ATOM   11139 C CG2 . VAL C 1 519 ? 85.481  111.624 112.525 1.00 7.60  ? 498  VAL C CG2 1 
ATOM   11140 N N   . SER C 1 520 ? 83.735  109.055 116.015 1.00 9.42  ? 499  SER C N   1 
ATOM   11141 C CA  . SER C 1 520 ? 83.323  107.845 116.715 1.00 9.42  ? 499  SER C CA  1 
ATOM   11142 C C   . SER C 1 520 ? 82.222  107.158 115.921 1.00 9.42  ? 499  SER C C   1 
ATOM   11143 O O   . SER C 1 520 ? 81.139  107.720 115.739 1.00 9.42  ? 499  SER C O   1 
ATOM   11144 C CB  . SER C 1 520 ? 82.844  108.164 118.128 1.00 9.42  ? 499  SER C CB  1 
ATOM   11145 O OG  . SER C 1 520 ? 82.450  106.988 118.806 1.00 9.42  ? 499  SER C OG  1 
ATOM   11146 N N   . TYR C 1 521 ? 82.505  105.947 115.453 1.00 9.21  ? 500  TYR C N   1 
ATOM   11147 C CA  . TYR C 1 521 ? 81.557  105.161 114.664 1.00 9.21  ? 500  TYR C CA  1 
ATOM   11148 C C   . TYR C 1 521 ? 80.813  104.160 115.545 1.00 9.21  ? 500  TYR C C   1 
ATOM   11149 O O   . TYR C 1 521 ? 80.925  102.947 115.387 1.00 9.21  ? 500  TYR C O   1 
ATOM   11150 C CB  . TYR C 1 521 ? 82.285  104.453 113.530 1.00 9.21  ? 500  TYR C CB  1 
ATOM   11151 C CG  . TYR C 1 521 ? 82.953  105.371 112.542 1.00 9.21  ? 500  TYR C CG  1 
ATOM   11152 C CD1 . TYR C 1 521 ? 82.208  106.086 111.621 1.00 9.21  ? 500  TYR C CD1 1 
ATOM   11153 C CD2 . TYR C 1 521 ? 84.330  105.520 112.525 1.00 9.21  ? 500  TYR C CD2 1 
ATOM   11154 C CE1 . TYR C 1 521 ? 82.813  106.918 110.711 1.00 9.21  ? 500  TYR C CE1 1 
ATOM   11155 C CE2 . TYR C 1 521 ? 84.946  106.347 111.615 1.00 9.21  ? 500  TYR C CE2 1 
ATOM   11156 C CZ  . TYR C 1 521 ? 84.181  107.043 110.710 1.00 9.21  ? 500  TYR C CZ  1 
ATOM   11157 O OH  . TYR C 1 521 ? 84.783  107.877 109.800 1.00 9.21  ? 500  TYR C OH  1 
ATOM   11158 N N   . SER C 1 522 ? 80.031  104.684 116.477 1.00 18.68 ? 501  SER C N   1 
ATOM   11159 C CA  . SER C 1 522 ? 79.274  103.823 117.376 1.00 18.68 ? 501  SER C CA  1 
ATOM   11160 C C   . SER C 1 522 ? 77.985  104.516 117.797 1.00 18.68 ? 501  SER C C   1 
ATOM   11161 O O   . SER C 1 522 ? 78.030  105.522 118.516 1.00 18.68 ? 501  SER C O   1 
ATOM   11162 C CB  . SER C 1 522 ? 80.111  103.454 118.600 1.00 18.68 ? 501  SER C CB  1 
ATOM   11163 O OG  . SER C 1 522 ? 80.084  104.490 119.565 1.00 18.68 ? 501  SER C OG  1 
ATOM   11164 N N   . PRO C 1 523 ? 76.824  104.023 117.356 1.00 24.34 ? 502  PRO C N   1 
ATOM   11165 C CA  . PRO C 1 523 ? 75.562  104.682 117.739 1.00 24.34 ? 502  PRO C CA  1 
ATOM   11166 C C   . PRO C 1 523 ? 75.346  104.751 119.241 1.00 24.34 ? 502  PRO C C   1 
ATOM   11167 O O   . PRO C 1 523 ? 74.833  105.760 119.742 1.00 24.34 ? 502  PRO C O   1 
ATOM   11168 C CB  . PRO C 1 523 ? 74.496  103.820 117.048 1.00 24.34 ? 502  PRO C CB  1 
ATOM   11169 C CG  . PRO C 1 523 ? 75.221  103.131 115.930 1.00 24.34 ? 502  PRO C CG  1 
ATOM   11170 C CD  . PRO C 1 523 ? 76.617  102.912 116.413 1.00 24.34 ? 502  PRO C CD  1 
ATOM   11171 N N   . LYS C 1 524 ? 75.726  103.710 119.973 1.00 26.40 ? 503  LYS C N   1 
ATOM   11172 C CA  . LYS C 1 524 ? 75.658  103.721 121.424 1.00 26.40 ? 503  LYS C CA  1 
ATOM   11173 C C   . LYS C 1 524 ? 76.980  104.199 122.011 1.00 26.40 ? 503  LYS C C   1 
ATOM   11174 O O   . LYS C 1 524 ? 78.004  104.268 121.326 1.00 26.40 ? 503  LYS C O   1 
ATOM   11175 C CB  . LYS C 1 524 ? 75.313  102.332 121.965 1.00 26.40 ? 503  LYS C CB  1 
ATOM   11176 C CG  . LYS C 1 524 ? 76.231  101.212 121.484 1.00 26.40 ? 503  LYS C CG  1 
ATOM   11177 C CD  . LYS C 1 524 ? 77.339  100.910 122.484 1.00 26.40 ? 503  LYS C CD  1 
ATOM   11178 C CE  . LYS C 1 524 ? 78.157  99.704  122.056 1.00 26.40 ? 503  LYS C CE  1 
ATOM   11179 N NZ  . LYS C 1 524 ? 79.281  99.421  122.991 1.00 26.40 ? 503  LYS C NZ  1 
ATOM   11180 N N   . LYS C 1 525 ? 76.950  104.528 123.297 1.00 27.43 ? 504  LYS C N   1 
ATOM   11181 C CA  . LYS C 1 525 ? 78.161  104.937 123.992 1.00 27.43 ? 504  LYS C CA  1 
ATOM   11182 C C   . LYS C 1 525 ? 78.569  103.893 125.026 1.00 27.43 ? 504  LYS C C   1 
ATOM   11183 O O   . LYS C 1 525 ? 77.961  102.828 125.118 1.00 27.43 ? 504  LYS C O   1 
ATOM   11184 C CB  . LYS C 1 525 ? 77.971  106.299 124.662 1.00 27.43 ? 504  LYS C CB  1 
ATOM   11185 C CG  . LYS C 1 525 ? 77.043  106.290 125.865 1.00 27.43 ? 504  LYS C CG  1 
ATOM   11186 C CD  . LYS C 1 525 ? 77.075  107.634 126.567 1.00 27.43 ? 504  LYS C CD  1 
ATOM   11187 C CE  . LYS C 1 525 ? 78.428  107.871 127.220 1.00 27.43 ? 504  LYS C CE  1 
ATOM   11188 N NZ  . LYS C 1 525 ? 78.537  109.225 127.824 1.00 27.43 ? 504  LYS C NZ  1 
ATOM   11189 N N   . GLY D 1 79  ? 118.711 130.688 143.543 1.00 25.54 ? 58   GLY D N   1 
ATOM   11190 C CA  . GLY D 1 79  ? 119.499 129.887 144.462 1.00 25.54 ? 58   GLY D CA  1 
ATOM   11191 C C   . GLY D 1 79  ? 119.071 128.435 144.485 1.00 25.54 ? 58   GLY D C   1 
ATOM   11192 O O   . GLY D 1 79  ? 119.783 127.560 143.992 1.00 25.54 ? 58   GLY D O   1 
ATOM   11193 N N   . ASP D 1 80  ? 117.902 128.179 145.076 1.00 26.70 ? 59   ASP D N   1 
ATOM   11194 C CA  . ASP D 1 80  ? 117.334 126.835 145.056 1.00 26.70 ? 59   ASP D CA  1 
ATOM   11195 C C   . ASP D 1 80  ? 117.088 126.381 143.621 1.00 26.70 ? 59   ASP D C   1 
ATOM   11196 O O   . ASP D 1 80  ? 117.469 125.270 143.228 1.00 26.70 ? 59   ASP D O   1 
ATOM   11197 C CB  . ASP D 1 80  ? 116.038 126.818 145.871 1.00 26.70 ? 59   ASP D CB  1 
ATOM   11198 C CG  . ASP D 1 80  ? 115.649 125.429 146.331 1.00 26.70 ? 59   ASP D CG  1 
ATOM   11199 O OD1 . ASP D 1 80  ? 116.411 124.476 146.069 1.00 26.70 ? 59   ASP D OD1 1 
ATOM   11200 O OD2 . ASP D 1 80  ? 114.577 125.294 146.959 1.00 26.70 ? 59   ASP D OD2 1 
ATOM   11201 N N   . ILE D 1 81  ? 116.475 127.249 142.815 1.00 26.77 ? 60   ILE D N   1 
ATOM   11202 C CA  . ILE D 1 81  ? 116.332 126.975 141.388 1.00 26.77 ? 60   ILE D CA  1 
ATOM   11203 C C   . ILE D 1 81  ? 117.700 126.920 140.721 1.00 26.77 ? 60   ILE D C   1 
ATOM   11204 O O   . ILE D 1 81  ? 117.926 126.132 139.795 1.00 26.77 ? 60   ILE D O   1 
ATOM   11205 C CB  . ILE D 1 81  ? 115.416 128.028 140.736 1.00 26.77 ? 60   ILE D CB  1 
ATOM   11206 C CG1 . ILE D 1 81  ? 113.994 127.905 141.284 1.00 26.77 ? 60   ILE D CG1 1 
ATOM   11207 C CG2 . ILE D 1 81  ? 115.413 127.891 139.225 1.00 26.77 ? 60   ILE D CG2 1 
ATOM   11208 C CD1 . ILE D 1 81  ? 113.171 126.829 140.615 1.00 26.77 ? 60   ILE D CD1 1 
ATOM   11209 N N   . GLU D 1 82  ? 118.639 127.750 141.183 1.00 26.17 ? 61   GLU D N   1 
ATOM   11210 C CA  . GLU D 1 82  ? 119.981 127.732 140.611 1.00 26.17 ? 61   GLU D CA  1 
ATOM   11211 C C   . GLU D 1 82  ? 120.684 126.404 140.874 1.00 26.17 ? 61   GLU D C   1 
ATOM   11212 O O   . GLU D 1 82  ? 121.341 125.856 139.980 1.00 26.17 ? 61   GLU D O   1 
ATOM   11213 C CB  . GLU D 1 82  ? 120.800 128.897 141.163 1.00 26.17 ? 61   GLU D CB  1 
ATOM   11214 C CG  . GLU D 1 82  ? 122.202 128.998 140.597 1.00 26.17 ? 61   GLU D CG  1 
ATOM   11215 C CD  . GLU D 1 82  ? 122.953 130.204 141.123 1.00 26.17 ? 61   GLU D CD  1 
ATOM   11216 O OE1 . GLU D 1 82  ? 122.379 130.954 141.938 1.00 26.17 ? 61   GLU D OE1 1 
ATOM   11217 O OE2 . GLU D 1 82  ? 124.119 130.403 140.721 1.00 26.17 ? 61   GLU D OE2 1 
ATOM   11218 N N   . LEU D 1 83  ? 120.559 125.863 142.088 1.00 22.58 ? 62   LEU D N   1 
ATOM   11219 C CA  . LEU D 1 83  ? 121.176 124.568 142.358 1.00 22.58 ? 62   LEU D CA  1 
ATOM   11220 C C   . LEU D 1 83  ? 120.443 123.442 141.640 1.00 22.58 ? 62   LEU D C   1 
ATOM   11221 O O   . LEU D 1 83  ? 121.071 122.456 141.231 1.00 22.58 ? 62   LEU D O   1 
ATOM   11222 C CB  . LEU D 1 83  ? 121.251 124.314 143.867 1.00 22.58 ? 62   LEU D CB  1 
ATOM   11223 C CG  . LEU D 1 83  ? 120.018 124.385 144.772 1.00 22.58 ? 62   LEU D CG  1 
ATOM   11224 C CD1 . LEU D 1 83  ? 119.237 123.082 144.782 1.00 22.58 ? 62   LEU D CD1 1 
ATOM   11225 C CD2 . LEU D 1 83  ? 120.428 124.770 146.183 1.00 22.58 ? 62   LEU D CD2 1 
ATOM   11226 N N   . ALA D 1 84  ? 119.127 123.577 141.456 1.00 21.24 ? 63   ALA D N   1 
ATOM   11227 C CA  . ALA D 1 84  ? 118.410 122.631 140.608 1.00 21.24 ? 63   ALA D CA  1 
ATOM   11228 C C   . ALA D 1 84  ? 118.980 122.635 139.195 1.00 21.24 ? 63   ALA D C   1 
ATOM   11229 O O   . ALA D 1 84  ? 119.219 121.576 138.606 1.00 21.24 ? 63   ALA D O   1 
ATOM   11230 C CB  . ALA D 1 84  ? 116.919 122.962 140.592 1.00 21.24 ? 63   ALA D CB  1 
ATOM   11231 N N   . LEU D 1 85  ? 119.218 123.827 138.641 1.00 19.85 ? 64   LEU D N   1 
ATOM   11232 C CA  . LEU D 1 85  ? 119.798 123.931 137.304 1.00 19.85 ? 64   LEU D CA  1 
ATOM   11233 C C   . LEU D 1 85  ? 121.197 123.330 137.255 1.00 19.85 ? 64   LEU D C   1 
ATOM   11234 O O   . LEU D 1 85  ? 121.568 122.677 136.272 1.00 19.85 ? 64   LEU D O   1 
ATOM   11235 C CB  . LEU D 1 85  ? 119.837 125.392 136.858 1.00 19.85 ? 64   LEU D CB  1 
ATOM   11236 C CG  . LEU D 1 85  ? 118.729 125.882 135.925 1.00 19.85 ? 64   LEU D CG  1 
ATOM   11237 C CD1 . LEU D 1 85  ? 118.985 127.320 135.507 1.00 19.85 ? 64   LEU D CD1 1 
ATOM   11238 C CD2 . LEU D 1 85  ? 118.613 124.990 134.713 1.00 19.85 ? 64   LEU D CD2 1 
ATOM   11239 N N   . ASP D 1 86  ? 121.999 123.567 138.293 1.00 21.65 ? 65   ASP D N   1 
ATOM   11240 C CA  . ASP D 1 86  ? 123.352 123.019 138.319 1.00 21.65 ? 65   ASP D CA  1 
ATOM   11241 C C   . ASP D 1 86  ? 123.322 121.494 138.320 1.00 21.65 ? 65   ASP D C   1 
ATOM   11242 O O   . ASP D 1 86  ? 124.064 120.841 137.569 1.00 21.65 ? 65   ASP D O   1 
ATOM   11243 C CB  . ASP D 1 86  ? 124.102 123.552 139.539 1.00 21.65 ? 65   ASP D CB  1 
ATOM   11244 C CG  . ASP D 1 86  ? 125.601 123.362 139.430 1.00 21.65 ? 65   ASP D CG  1 
ATOM   11245 O OD1 . ASP D 1 86  ? 126.054 122.657 138.503 1.00 21.65 ? 65   ASP D OD1 1 
ATOM   11246 O OD2 . ASP D 1 86  ? 126.329 123.925 140.274 1.00 21.65 ? 65   ASP D OD2 1 
ATOM   11247 N N   . ALA D 1 87  ? 122.455 120.908 139.152 1.00 19.68 ? 66   ALA D N   1 
ATOM   11248 C CA  . ALA D 1 87  ? 122.293 119.458 139.147 1.00 19.68 ? 66   ALA D CA  1 
ATOM   11249 C C   . ALA D 1 87  ? 121.817 118.966 137.785 1.00 19.68 ? 66   ALA D C   1 
ATOM   11250 O O   . ALA D 1 87  ? 122.296 117.942 137.279 1.00 19.68 ? 66   ALA D O   1 
ATOM   11251 C CB  . ALA D 1 87  ? 121.316 119.035 140.243 1.00 19.68 ? 66   ALA D CB  1 
ATOM   11252 N N   . ALA D 1 88  ? 120.873 119.689 137.179 1.00 17.65 ? 67   ALA D N   1 
ATOM   11253 C CA  . ALA D 1 88  ? 120.341 119.284 135.885 1.00 17.65 ? 67   ALA D CA  1 
ATOM   11254 C C   . ALA D 1 88  ? 121.427 119.270 134.822 1.00 17.65 ? 67   ALA D C   1 
ATOM   11255 O O   . ALA D 1 88  ? 121.468 118.365 133.990 1.00 17.65 ? 67   ALA D O   1 
ATOM   11256 C CB  . ALA D 1 88  ? 119.196 120.207 135.474 1.00 17.65 ? 67   ALA D CB  1 
ATOM   11257 N N   . HIS D 1 89  ? 122.316 120.264 134.829 1.00 18.28 ? 68   HIS D N   1 
ATOM   11258 C CA  . HIS D 1 89  ? 123.405 120.279 133.852 1.00 18.28 ? 68   HIS D CA  1 
ATOM   11259 C C   . HIS D 1 89  ? 124.386 119.139 134.103 1.00 18.28 ? 68   HIS D C   1 
ATOM   11260 O O   . HIS D 1 89  ? 124.795 118.432 133.166 1.00 18.28 ? 68   HIS D O   1 
ATOM   11261 C CB  . HIS D 1 89  ? 124.123 121.628 133.885 1.00 18.28 ? 68   HIS D CB  1 
ATOM   11262 C CG  . HIS D 1 89  ? 123.323 122.750 133.304 1.00 18.28 ? 68   HIS D CG  1 
ATOM   11263 N ND1 . HIS D 1 89  ? 122.343 123.410 134.013 1.00 18.28 ? 68   HIS D ND1 1 
ATOM   11264 C CD2 . HIS D 1 89  ? 123.349 123.320 132.077 1.00 18.28 ? 68   HIS D CD2 1 
ATOM   11265 C CE1 . HIS D 1 89  ? 121.803 124.342 133.250 1.00 18.28 ? 68   HIS D CE1 1 
ATOM   11266 N NE2 . HIS D 1 89  ? 122.394 124.308 132.069 1.00 18.28 ? 68   HIS D NE2 1 
ATOM   11267 N N   . ALA D 1 90  ? 124.765 118.942 135.370 1.00 17.49 ? 69   ALA D N   1 
ATOM   11268 C CA  . ALA D 1 90  ? 125.669 117.850 135.714 1.00 17.49 ? 69   ALA D CA  1 
ATOM   11269 C C   . ALA D 1 90  ? 125.123 116.506 135.245 1.00 17.49 ? 69   ALA D C   1 
ATOM   11270 O O   . ALA D 1 90  ? 125.879 115.649 134.775 1.00 17.49 ? 69   ALA D O   1 
ATOM   11271 C CB  . ALA D 1 90  ? 125.914 117.831 137.223 1.00 17.49 ? 69   ALA D CB  1 
ATOM   11272 N N   . ALA D 1 91  ? 123.809 116.306 135.363 1.00 15.40 ? 70   ALA D N   1 
ATOM   11273 C CA  . ALA D 1 91  ? 123.206 115.070 134.873 1.00 15.40 ? 70   ALA D CA  1 
ATOM   11274 C C   . ALA D 1 91  ? 123.078 115.065 133.353 1.00 15.40 ? 70   ALA D C   1 
ATOM   11275 O O   . ALA D 1 91  ? 123.237 114.016 132.720 1.00 15.40 ? 70   ALA D O   1 
ATOM   11276 C CB  . ALA D 1 91  ? 121.840 114.859 135.520 1.00 15.40 ? 70   ALA D CB  1 
ATOM   11277 N N   . LYS D 1 92  ? 122.798 116.226 132.757 1.00 16.13 ? 71   LYS D N   1 
ATOM   11278 C CA  . LYS D 1 92  ? 122.670 116.337 131.308 1.00 16.13 ? 71   LYS D CA  1 
ATOM   11279 C C   . LYS D 1 92  ? 123.939 115.902 130.601 1.00 16.13 ? 71   LYS D C   1 
ATOM   11280 O O   . LYS D 1 92  ? 123.877 115.389 129.478 1.00 16.13 ? 71   LYS D O   1 
ATOM   11281 C CB  . LYS D 1 92  ? 122.308 117.776 130.935 1.00 16.13 ? 71   LYS D CB  1 
ATOM   11282 C CG  . LYS D 1 92  ? 122.899 118.266 129.626 1.00 16.13 ? 71   LYS D CG  1 
ATOM   11283 C CD  . LYS D 1 92  ? 122.883 119.780 129.543 1.00 16.13 ? 71   LYS D CD  1 
ATOM   11284 C CE  . LYS D 1 92  ? 123.720 120.269 128.378 1.00 16.13 ? 71   LYS D CE  1 
ATOM   11285 N NZ  . LYS D 1 92  ? 123.668 121.749 128.234 1.00 16.13 ? 71   LYS D NZ  1 
ATOM   11286 N N   . GLU D 1 93  ? 125.093 116.091 131.241 1.00 19.17 ? 72   GLU D N   1 
ATOM   11287 C CA  . GLU D 1 93  ? 126.331 115.562 130.675 1.00 19.17 ? 72   GLU D CA  1 
ATOM   11288 C C   . GLU D 1 93  ? 126.188 114.079 130.333 1.00 19.17 ? 72   GLU D C   1 
ATOM   11289 O O   . GLU D 1 93  ? 126.645 113.626 129.278 1.00 19.17 ? 72   GLU D O   1 
ATOM   11290 C CB  . GLU D 1 93  ? 127.488 115.777 131.654 1.00 19.17 ? 72   GLU D CB  1 
ATOM   11291 C CG  . GLU D 1 93  ? 127.828 117.241 131.932 1.00 19.17 ? 72   GLU D CG  1 
ATOM   11292 C CD  . GLU D 1 93  ? 128.404 117.961 130.728 1.00 19.17 ? 72   GLU D CD  1 
ATOM   11293 O OE1 . GLU D 1 93  ? 129.099 117.314 129.918 1.00 19.17 ? 72   GLU D OE1 1 
ATOM   11294 O OE2 . GLU D 1 93  ? 128.161 119.178 130.594 1.00 19.17 ? 72   GLU D OE2 1 
ATOM   11295 N N   . LYS D 1 94  ? 125.524 113.315 131.204 1.00 14.80 ? 73   LYS D N   1 
ATOM   11296 C CA  . LYS D 1 94  ? 125.455 111.860 131.102 1.00 14.80 ? 73   LYS D CA  1 
ATOM   11297 C C   . LYS D 1 94  ? 124.129 111.345 130.553 1.00 14.80 ? 73   LYS D C   1 
ATOM   11298 O O   . LYS D 1 94  ? 124.109 110.329 129.851 1.00 14.80 ? 73   LYS D O   1 
ATOM   11299 C CB  . LYS D 1 94  ? 125.703 111.233 132.475 1.00 14.80 ? 73   LYS D CB  1 
ATOM   11300 C CG  . LYS D 1 94  ? 126.442 109.912 132.433 1.00 14.80 ? 73   LYS D CG  1 
ATOM   11301 C CD  . LYS D 1 94  ? 126.376 109.222 133.780 1.00 14.80 ? 73   LYS D CD  1 
ATOM   11302 C CE  . LYS D 1 94  ? 126.914 107.810 133.706 1.00 14.80 ? 73   LYS D CE  1 
ATOM   11303 N NZ  . LYS D 1 94  ? 126.205 106.903 134.648 1.00 14.80 ? 73   LYS D NZ  1 
ATOM   11304 N N   . TRP D 1 95  ? 123.015 112.005 130.879 1.00 10.65 ? 74   TRP D N   1 
ATOM   11305 C CA  . TRP D 1 95  ? 121.702 111.504 130.478 1.00 10.65 ? 74   TRP D CA  1 
ATOM   11306 C C   . TRP D 1 95  ? 121.552 111.465 128.961 1.00 10.65 ? 74   TRP D C   1 
ATOM   11307 O O   . TRP D 1 95  ? 120.983 110.516 128.413 1.00 10.65 ? 74   TRP D O   1 
ATOM   11308 C CB  . TRP D 1 95  ? 120.610 112.367 131.103 1.00 10.65 ? 74   TRP D CB  1 
ATOM   11309 C CG  . TRP D 1 95  ? 119.214 111.909 130.838 1.00 10.65 ? 74   TRP D CG  1 
ATOM   11310 C CD1 . TRP D 1 95  ? 118.260 112.580 130.141 1.00 10.65 ? 74   TRP D CD1 1 
ATOM   11311 C CD2 . TRP D 1 95  ? 118.599 110.698 131.293 1.00 10.65 ? 74   TRP D CD2 1 
ATOM   11312 N NE1 . TRP D 1 95  ? 117.093 111.861 130.119 1.00 10.65 ? 74   TRP D NE1 1 
ATOM   11313 C CE2 . TRP D 1 95  ? 117.276 110.701 130.821 1.00 10.65 ? 74   TRP D CE2 1 
ATOM   11314 C CE3 . TRP D 1 95  ? 119.039 109.612 132.050 1.00 10.65 ? 74   TRP D CE3 1 
ATOM   11315 C CZ2 . TRP D 1 95  ? 116.391 109.661 131.079 1.00 10.65 ? 74   TRP D CZ2 1 
ATOM   11316 C CZ3 . TRP D 1 95  ? 118.158 108.580 132.301 1.00 10.65 ? 74   TRP D CZ3 1 
ATOM   11317 C CH2 . TRP D 1 95  ? 116.852 108.611 131.819 1.00 10.65 ? 74   TRP D CH2 1 
ATOM   11318 N N   . GLY D 1 96  ? 122.049 112.488 128.267 1.00 11.02 ? 75   GLY D N   1 
ATOM   11319 C CA  . GLY D 1 96  ? 121.963 112.506 126.818 1.00 11.02 ? 75   GLY D CA  1 
ATOM   11320 C C   . GLY D 1 96  ? 122.767 111.415 126.147 1.00 11.02 ? 75   GLY D C   1 
ATOM   11321 O O   . GLY D 1 96  ? 122.514 111.095 124.981 1.00 11.02 ? 75   GLY D O   1 
ATOM   11322 N N   . ALA D 1 97  ? 123.739 110.840 126.853 1.00 12.07 ? 76   ALA D N   1 
ATOM   11323 C CA  . ALA D 1 97  ? 124.497 109.719 126.320 1.00 12.07 ? 76   ALA D CA  1 
ATOM   11324 C C   . ALA D 1 97  ? 123.724 108.410 126.378 1.00 12.07 ? 76   ALA D C   1 
ATOM   11325 O O   . ALA D 1 97  ? 124.069 107.468 125.656 1.00 12.07 ? 76   ALA D O   1 
ATOM   11326 C CB  . ALA D 1 97  ? 125.817 109.573 127.081 1.00 12.07 ? 76   ALA D CB  1 
ATOM   11327 N N   . THR D 1 98  ? 122.692 108.332 127.212 1.00 9.19  ? 77   THR D N   1 
ATOM   11328 C CA  . THR D 1 98  ? 121.955 107.092 127.388 1.00 9.19  ? 77   THR D CA  1 
ATOM   11329 C C   . THR D 1 98  ? 121.216 106.718 126.108 1.00 9.19  ? 77   THR D C   1 
ATOM   11330 O O   . THR D 1 98  ? 120.664 107.575 125.414 1.00 9.19  ? 77   THR D O   1 
ATOM   11331 C CB  . THR D 1 98  ? 120.975 107.232 128.550 1.00 9.19  ? 77   THR D CB  1 
ATOM   11332 O OG1 . THR D 1 98  ? 121.702 107.527 129.747 1.00 9.19  ? 77   THR D OG1 1 
ATOM   11333 C CG2 . THR D 1 98  ? 120.218 105.954 128.766 1.00 9.19  ? 77   THR D CG2 1 
ATOM   11334 N N   . SER D 1 99  ? 121.215 105.425 125.797 1.00 6.76  ? 78   SER D N   1 
ATOM   11335 C CA  . SER D 1 99  ? 120.586 104.942 124.584 1.00 6.76  ? 78   SER D CA  1 
ATOM   11336 C C   . SER D 1 99  ? 119.082 105.195 124.632 1.00 6.76  ? 78   SER D C   1 
ATOM   11337 O O   . SER D 1 99  ? 118.491 105.257 125.712 1.00 6.76  ? 78   SER D O   1 
ATOM   11338 C CB  . SER D 1 99  ? 120.848 103.450 124.413 1.00 6.76  ? 78   SER D CB  1 
ATOM   11339 O OG  . SER D 1 99  ? 122.217 103.156 124.583 1.00 6.76  ? 78   SER D OG  1 
ATOM   11340 N N   . PRO D 1 100 ? 118.436 105.355 123.474 1.00 5.90  ? 79   PRO D N   1 
ATOM   11341 C CA  . PRO D 1 100 ? 116.969 105.442 123.476 1.00 5.90  ? 79   PRO D CA  1 
ATOM   11342 C C   . PRO D 1 100 ? 116.314 104.212 124.074 1.00 5.90  ? 79   PRO D C   1 
ATOM   11343 O O   . PRO D 1 100 ? 115.288 104.322 124.757 1.00 5.90  ? 79   PRO D O   1 
ATOM   11344 C CB  . PRO D 1 100 ? 116.637 105.608 121.988 1.00 5.90  ? 79   PRO D CB  1 
ATOM   11345 C CG  . PRO D 1 100 ? 117.877 106.160 121.392 1.00 5.90  ? 79   PRO D CG  1 
ATOM   11346 C CD  . PRO D 1 100 ? 118.984 105.484 122.116 1.00 5.90  ? 79   PRO D CD  1 
ATOM   11347 N N   . ALA D 1 101 ? 116.901 103.036 123.843 1.00 5.59  ? 80   ALA D N   1 
ATOM   11348 C CA  . ALA D 1 101 ? 116.373 101.810 124.425 1.00 5.59  ? 80   ALA D CA  1 
ATOM   11349 C C   . ALA D 1 101 ? 116.392 101.868 125.944 1.00 5.59  ? 80   ALA D C   1 
ATOM   11350 O O   . ALA D 1 101 ? 115.424 101.471 126.599 1.00 5.59  ? 80   ALA D O   1 
ATOM   11351 C CB  . ALA D 1 101 ? 117.177 100.611 123.931 1.00 5.59  ? 80   ALA D CB  1 
ATOM   11352 N N   . GLU D 1 102 ? 117.482 102.375 126.522 1.00 7.73  ? 81   GLU D N   1 
ATOM   11353 C CA  . GLU D 1 102 ? 117.616 102.385 127.974 1.00 7.73  ? 81   GLU D CA  1 
ATOM   11354 C C   . GLU D 1 102 ? 116.674 103.394 128.618 1.00 7.73  ? 81   GLU D C   1 
ATOM   11355 O O   . GLU D 1 102 ? 116.080 103.112 129.665 1.00 7.73  ? 81   GLU D O   1 
ATOM   11356 C CB  . GLU D 1 102 ? 119.066 102.666 128.354 1.00 7.73  ? 81   GLU D CB  1 
ATOM   11357 C CG  . GLU D 1 102 ? 119.983 101.473 128.137 1.00 7.73  ? 81   GLU D CG  1 
ATOM   11358 C CD  . GLU D 1 102 ? 121.440 101.785 128.411 1.00 7.73  ? 81   GLU D CD  1 
ATOM   11359 O OE1 . GLU D 1 102 ? 121.859 102.940 128.188 1.00 7.73  ? 81   GLU D OE1 1 
ATOM   11360 O OE2 . GLU D 1 102 ? 122.167 100.870 128.850 1.00 7.73  ? 81   GLU D OE2 1 
ATOM   11361 N N   . ARG D 1 103 ? 116.506 104.566 128.002 1.00 6.13  ? 82   ARG D N   1 
ATOM   11362 C CA  . ARG D 1 103 ? 115.554 105.540 128.528 1.00 6.13  ? 82   ARG D CA  1 
ATOM   11363 C C   . ARG D 1 103 ? 114.121 105.041 128.392 1.00 6.13  ? 82   ARG D C   1 
ATOM   11364 O O   . ARG D 1 103 ? 113.296 105.249 129.289 1.00 6.13  ? 82   ARG D O   1 
ATOM   11365 C CB  . ARG D 1 103 ? 115.720 106.880 127.819 1.00 6.13  ? 82   ARG D CB  1 
ATOM   11366 C CG  . ARG D 1 103 ? 117.051 107.544 128.061 1.00 6.13  ? 82   ARG D CG  1 
ATOM   11367 C CD  . ARG D 1 103 ? 117.016 108.986 127.633 1.00 6.13  ? 82   ARG D CD  1 
ATOM   11368 N NE  . ARG D 1 103 ? 116.536 109.142 126.266 1.00 6.13  ? 82   ARG D NE  1 
ATOM   11369 C CZ  . ARG D 1 103 ? 117.321 109.384 125.225 1.00 6.13  ? 82   ARG D CZ  1 
ATOM   11370 N NH1 . ARG D 1 103 ? 118.627 109.497 125.393 1.00 6.13  ? 82   ARG D NH1 1 
ATOM   11371 N NH2 . ARG D 1 103 ? 116.799 109.516 124.018 1.00 6.13  ? 82   ARG D NH2 1 
ATOM   11372 N N   . ALA D 1 104 ? 113.807 104.379 127.276 1.00 6.91  ? 83   ALA D N   1 
ATOM   11373 C CA  . ALA D 1 104 ? 112.484 103.787 127.118 1.00 6.91  ? 83   ALA D CA  1 
ATOM   11374 C C   . ALA D 1 104 ? 112.236 102.704 128.156 1.00 6.91  ? 83   ALA D C   1 
ATOM   11375 O O   . ALA D 1 104 ? 111.129 102.587 128.690 1.00 6.91  ? 83   ALA D O   1 
ATOM   11376 C CB  . ALA D 1 104 ? 112.330 103.221 125.711 1.00 6.91  ? 83   ALA D CB  1 
ATOM   11377 N N   . ASN D 1 105 ? 113.251 101.890 128.445 1.00 7.49  ? 84   ASN D N   1 
ATOM   11378 C CA  . ASN D 1 105 ? 113.112 100.873 129.479 1.00 7.49  ? 84   ASN D CA  1 
ATOM   11379 C C   . ASN D 1 105 ? 112.885 101.502 130.844 1.00 7.49  ? 84   ASN D C   1 
ATOM   11380 O O   . ASN D 1 105 ? 112.078 101.006 131.639 1.00 7.49  ? 84   ASN D O   1 
ATOM   11381 C CB  . ASN D 1 105 ? 114.348 99.979  129.499 1.00 7.49  ? 84   ASN D CB  1 
ATOM   11382 C CG  . ASN D 1 105 ? 114.374 99.009  128.346 1.00 7.49  ? 84   ASN D CG  1 
ATOM   11383 O OD1 . ASN D 1 105 ? 113.336 98.679  127.778 1.00 7.49  ? 84   ASN D OD1 1 
ATOM   11384 N ND2 . ASN D 1 105 ? 115.563 98.543  127.992 1.00 7.49  ? 84   ASN D ND2 1 
ATOM   11385 N N   . ILE D 1 106 ? 113.597 102.591 131.139 1.00 8.19  ? 85   ILE D N   1 
ATOM   11386 C CA  . ILE D 1 106 ? 113.384 103.296 132.399 1.00 8.19  ? 85   ILE D CA  1 
ATOM   11387 C C   . ILE D 1 106 ? 111.955 103.822 132.475 1.00 8.19  ? 85   ILE D C   1 
ATOM   11388 O O   . ILE D 1 106 ? 111.308 103.759 133.527 1.00 8.19  ? 85   ILE D O   1 
ATOM   11389 C CB  . ILE D 1 106 ? 114.423 104.419 132.559 1.00 8.19  ? 85   ILE D CB  1 
ATOM   11390 C CG1 . ILE D 1 106 ? 115.779 103.824 132.924 1.00 8.19  ? 85   ILE D CG1 1 
ATOM   11391 C CG2 . ILE D 1 106 ? 113.993 105.406 133.622 1.00 8.19  ? 85   ILE D CG2 1 
ATOM   11392 C CD1 . ILE D 1 106 ? 116.921 104.792 132.800 1.00 8.19  ? 85   ILE D CD1 1 
ATOM   11393 N N   . MET D 1 107 ? 111.432 104.325 131.356 1.00 9.36  ? 86   MET D N   1 
ATOM   11394 C CA  . MET D 1 107 ? 110.051 104.799 131.344 1.00 9.36  ? 86   MET D CA  1 
ATOM   11395 C C   . MET D 1 107 ? 109.061 103.658 131.546 1.00 9.36  ? 86   MET D C   1 
ATOM   11396 O O   . MET D 1 107 ? 108.033 103.831 132.212 1.00 9.36  ? 86   MET D O   1 
ATOM   11397 C CB  . MET D 1 107 ? 109.751 105.528 130.040 1.00 9.36  ? 86   MET D CB  1 
ATOM   11398 C CG  . MET D 1 107 ? 110.268 106.940 129.985 1.00 9.36  ? 86   MET D CG  1 
ATOM   11399 S SD  . MET D 1 107 ? 110.515 107.442 128.284 1.00 9.36  ? 86   MET D SD  1 
ATOM   11400 C CE  . MET D 1 107 ? 108.984 108.319 128.038 1.00 9.36  ? 86   MET D CE  1 
ATOM   11401 N N   . LEU D 1 108 ? 109.340 102.491 130.970 1.00 8.22  ? 87   LEU D N   1 
ATOM   11402 C CA  . LEU D 1 108 ? 108.458 101.349 131.187 1.00 8.22  ? 87   LEU D CA  1 
ATOM   11403 C C   . LEU D 1 108 ? 108.478 100.916 132.647 1.00 8.22  ? 87   LEU D C   1 
ATOM   11404 O O   . LEU D 1 108 ? 107.439 100.552 133.210 1.00 8.22  ? 87   LEU D O   1 
ATOM   11405 C CB  . LEU D 1 108 ? 108.854 100.193 130.273 1.00 8.22  ? 87   LEU D CB  1 
ATOM   11406 C CG  . LEU D 1 108 ? 108.677 100.442 128.776 1.00 8.22  ? 87   LEU D CG  1 
ATOM   11407 C CD1 . LEU D 1 108 ? 108.971 99.188  128.002 1.00 8.22  ? 87   LEU D CD1 1 
ATOM   11408 C CD2 . LEU D 1 108 ? 107.282 100.942 128.472 1.00 8.22  ? 87   LEU D CD2 1 
ATOM   11409 N N   . LYS D 1 109 ? 109.653 100.955 133.277 1.00 10.03 ? 88   LYS D N   1 
ATOM   11410 C CA  . LYS D 1 109 ? 109.736 100.650 134.701 1.00 10.03 ? 88   LYS D CA  1 
ATOM   11411 C C   . LYS D 1 109 ? 108.971 101.674 135.528 1.00 10.03 ? 88   LYS D C   1 
ATOM   11412 O O   . LYS D 1 109 ? 108.341 101.325 136.533 1.00 10.03 ? 88   LYS D O   1 
ATOM   11413 C CB  . LYS D 1 109 ? 111.193 100.584 135.143 1.00 10.03 ? 88   LYS D CB  1 
ATOM   11414 C CG  . LYS D 1 109 ? 111.941 99.430  134.539 1.00 10.03 ? 88   LYS D CG  1 
ATOM   11415 C CD  . LYS D 1 109 ? 113.364 99.362  135.040 1.00 10.03 ? 88   LYS D CD  1 
ATOM   11416 C CE  . LYS D 1 109 ? 114.110 98.236  134.346 1.00 10.03 ? 88   LYS D CE  1 
ATOM   11417 N NZ  . LYS D 1 109 ? 113.579 96.903  134.736 1.00 10.03 ? 88   LYS D NZ  1 
ATOM   11418 N N   . ILE D 1 110 ? 109.017 102.944 135.120 1.00 12.24 ? 89   ILE D N   1 
ATOM   11419 C CA  . ILE D 1 110 ? 108.236 103.971 135.804 1.00 12.24 ? 89   ILE D CA  1 
ATOM   11420 C C   . ILE D 1 110 ? 106.748 103.675 135.692 1.00 12.24 ? 89   ILE D C   1 
ATOM   11421 O O   . ILE D 1 110 ? 106.002 103.778 136.673 1.00 12.24 ? 89   ILE D O   1 
ATOM   11422 C CB  . ILE D 1 110 ? 108.572 105.364 135.244 1.00 12.24 ? 89   ILE D CB  1 
ATOM   11423 C CG1 . ILE D 1 110 ? 109.959 105.816 135.705 1.00 12.24 ? 89   ILE D CG1 1 
ATOM   11424 C CG2 . ILE D 1 110 ? 107.507 106.359 135.647 1.00 12.24 ? 89   ILE D CG2 1 
ATOM   11425 C CD1 . ILE D 1 110 ? 110.527 106.957 134.897 1.00 12.24 ? 89   ILE D CD1 1 
ATOM   11426 N N   . ALA D 1 111 ? 106.292 103.306 134.495 1.00 13.54 ? 90   ALA D N   1 
ATOM   11427 C CA  . ALA D 1 111 ? 104.881 102.983 134.313 1.00 13.54 ? 90   ALA D CA  1 
ATOM   11428 C C   . ALA D 1 111 ? 104.477 101.772 135.147 1.00 13.54 ? 90   ALA D C   1 
ATOM   11429 O O   . ALA D 1 111 ? 103.394 101.754 135.744 1.00 13.54 ? 90   ALA D O   1 
ATOM   11430 C CB  . ALA D 1 111 ? 104.583 102.742 132.836 1.00 13.54 ? 90   ALA D CB  1 
ATOM   11431 N N   . ASP D 1 112 ? 105.332 100.748 135.198 1.00 19.23 ? 91   ASP D N   1 
ATOM   11432 C CA  . ASP D 1 112 ? 105.056 99.586  136.040 1.00 19.23 ? 91   ASP D CA  1 
ATOM   11433 C C   . ASP D 1 112 ? 104.916 99.988  137.502 1.00 19.23 ? 91   ASP D C   1 
ATOM   11434 O O   . ASP D 1 112 ? 103.942 99.619  138.175 1.00 19.23 ? 91   ASP D O   1 
ATOM   11435 C CB  . ASP D 1 112 ? 106.167 98.549  135.880 1.00 19.23 ? 91   ASP D CB  1 
ATOM   11436 C CG  . ASP D 1 112 ? 106.038 97.747  134.601 1.00 19.23 ? 91   ASP D CG  1 
ATOM   11437 O OD1 . ASP D 1 112 ? 105.017 97.047  134.439 1.00 19.23 ? 91   ASP D OD1 1 
ATOM   11438 O OD2 . ASP D 1 112 ? 106.962 97.808  133.765 1.00 19.23 ? 91   ASP D OD2 1 
ATOM   11439 N N   . ARG D 1 113 ? 105.887 100.750 138.010 1.00 18.80 ? 92   ARG D N   1 
ATOM   11440 C CA  . ARG D 1 113 ? 105.850 101.167 139.405 1.00 18.80 ? 92   ARG D CA  1 
ATOM   11441 C C   . ARG D 1 113 ? 104.635 102.033 139.695 1.00 18.80 ? 92   ARG D C   1 
ATOM   11442 O O   . ARG D 1 113 ? 104.095 101.993 140.807 1.00 18.80 ? 92   ARG D O   1 
ATOM   11443 C CB  . ARG D 1 113 ? 107.133 101.913 139.760 1.00 18.80 ? 92   ARG D CB  1 
ATOM   11444 C CG  . ARG D 1 113 ? 107.279 102.206 141.235 1.00 18.80 ? 92   ARG D CG  1 
ATOM   11445 C CD  . ARG D 1 113 ? 108.589 102.894 141.532 1.00 18.80 ? 92   ARG D CD  1 
ATOM   11446 N NE  . ARG D 1 113 ? 109.700 101.957 141.631 1.00 18.80 ? 92   ARG D NE  1 
ATOM   11447 C CZ  . ARG D 1 113 ? 110.913 102.288 142.059 1.00 18.80 ? 92   ARG D CZ  1 
ATOM   11448 N NH1 . ARG D 1 113 ? 111.169 103.534 142.428 1.00 18.80 ? 92   ARG D NH1 1 
ATOM   11449 N NH2 . ARG D 1 113 ? 111.870 101.375 142.119 1.00 18.80 ? 92   ARG D NH2 1 
ATOM   11450 N N   . MET D 1 114 ? 104.188 102.819 138.715 1.00 18.77 ? 93   MET D N   1 
ATOM   11451 C CA  . MET D 1 114 ? 102.987 103.620 138.913 1.00 18.77 ? 93   MET D CA  1 
ATOM   11452 C C   . MET D 1 114 ? 101.739 102.745 138.927 1.00 18.77 ? 93   MET D C   1 
ATOM   11453 O O   . MET D 1 114 ? 100.788 103.027 139.663 1.00 18.77 ? 93   MET D O   1 
ATOM   11454 C CB  . MET D 1 114 ? 102.893 104.698 137.835 1.00 18.77 ? 93   MET D CB  1 
ATOM   11455 C CG  . MET D 1 114 ? 103.600 105.987 138.206 1.00 18.77 ? 93   MET D CG  1 
ATOM   11456 S SD  . MET D 1 114 ? 103.857 107.087 136.808 1.00 18.77 ? 93   MET D SD  1 
ATOM   11457 C CE  . MET D 1 114 ? 102.181 107.320 136.241 1.00 18.77 ? 93   MET D CE  1 
ATOM   11458 N N   . GLU D 1 115 ? 101.720 101.683 138.116 1.00 21.93 ? 94   GLU D N   1 
ATOM   11459 C CA  . GLU D 1 115 ? 100.618 100.725 138.185 1.00 21.93 ? 94   GLU D CA  1 
ATOM   11460 C C   . GLU D 1 115 ? 100.534 100.086 139.563 1.00 21.93 ? 94   GLU D C   1 
ATOM   11461 O O   . GLU D 1 115 ? 99.445  99.947  140.131 1.00 21.93 ? 94   GLU D O   1 
ATOM   11462 C CB  . GLU D 1 115 ? 100.773 99.634  137.127 1.00 21.93 ? 94   GLU D CB  1 
ATOM   11463 C CG  . GLU D 1 115 ? 100.326 99.999  135.735 1.00 21.93 ? 94   GLU D CG  1 
ATOM   11464 C CD  . GLU D 1 115 ? 100.319 98.794  134.822 1.00 21.93 ? 94   GLU D CD  1 
ATOM   11465 O OE1 . GLU D 1 115 ? 100.763 97.714  135.264 1.00 21.93 ? 94   GLU D OE1 1 
ATOM   11466 O OE2 . GLU D 1 115 ? 99.880  98.924  133.660 1.00 21.93 ? 94   GLU D OE2 1 
ATOM   11467 N N   . ARG D 1 116 ? 101.680 99.676  140.110 1.00 23.23 ? 95   ARG D N   1 
ATOM   11468 C CA  . ARG D 1 116 ? 101.671 99.024  141.415 1.00 23.23 ? 95   ARG D CA  1 
ATOM   11469 C C   . ARG D 1 116 ? 101.072 99.919  142.493 1.00 23.23 ? 95   ARG D C   1 
ATOM   11470 O O   . ARG D 1 116 ? 100.408 99.424  143.411 1.00 23.23 ? 95   ARG D O   1 
ATOM   11471 C CB  . ARG D 1 116 ? 103.085 98.601  141.801 1.00 23.23 ? 95   ARG D CB  1 
ATOM   11472 C CG  . ARG D 1 116 ? 103.456 97.230  141.292 1.00 23.23 ? 95   ARG D CG  1 
ATOM   11473 C CD  . ARG D 1 116 ? 104.962 97.035  141.284 1.00 23.23 ? 95   ARG D CD  1 
ATOM   11474 N NE  . ARG D 1 116 ? 105.353 95.727  140.766 1.00 23.23 ? 95   ARG D NE  1 
ATOM   11475 C CZ  . ARG D 1 116 ? 105.189 95.334  139.506 1.00 23.23 ? 95   ARG D CZ  1 
ATOM   11476 N NH1 . ARG D 1 116 ? 104.651 96.150  138.611 1.00 23.23 ? 95   ARG D NH1 1 
ATOM   11477 N NH2 . ARG D 1 116 ? 105.578 94.122  139.135 1.00 23.23 ? 95   ARG D NH2 1 
ATOM   11478 N N   . ASN D 1 117 ? 101.280 101.231 142.400 1.00 24.68 ? 96   ASN D N   1 
ATOM   11479 C CA  . ASN D 1 117 ? 100.766 102.170 143.388 1.00 24.68 ? 96   ASN D CA  1 
ATOM   11480 C C   . ASN D 1 117 ? 99.534  102.920 142.905 1.00 24.68 ? 96   ASN D C   1 
ATOM   11481 O O   . ASN D 1 117 ? 99.171  103.940 143.498 1.00 24.68 ? 96   ASN D O   1 
ATOM   11482 C CB  . ASN D 1 117 ? 101.851 103.161 143.795 1.00 24.68 ? 96   ASN D CB  1 
ATOM   11483 C CG  . ASN D 1 117 ? 102.814 102.577 144.794 1.00 24.68 ? 96   ASN D CG  1 
ATOM   11484 O OD1 . ASN D 1 117 ? 103.291 101.454 144.628 1.00 24.68 ? 96   ASN D OD1 1 
ATOM   11485 N ND2 . ASN D 1 117 ? 103.101 103.329 145.849 1.00 24.68 ? 96   ASN D ND2 1 
ATOM   11486 N N   . LEU D 1 118 ? 98.880  102.438 141.855 1.00 28.17 ? 97   LEU D N   1 
ATOM   11487 C CA  . LEU D 1 118 ? 97.635  103.028 141.379 1.00 28.17 ? 97   LEU D CA  1 
ATOM   11488 C C   . LEU D 1 118 ? 96.506  102.832 142.394 1.00 28.17 ? 97   LEU D C   1 
ATOM   11489 O O   . LEU D 1 118 ? 96.742  102.527 143.564 1.00 28.17 ? 97   LEU D O   1 
ATOM   11490 C CB  . LEU D 1 118 ? 97.249  102.417 140.029 1.00 28.17 ? 97   LEU D CB  1 
ATOM   11491 C CG  . LEU D 1 118 ? 95.813  102.524 139.508 1.00 28.17 ? 97   LEU D CG  1 
ATOM   11492 C CD1 . LEU D 1 118 ? 95.311  103.960 139.491 1.00 28.17 ? 97   LEU D CD1 1 
ATOM   11493 C CD2 . LEU D 1 118 ? 95.712  101.899 138.126 1.00 28.17 ? 97   LEU D CD2 1 
ATOM   11494 N N   . ALA D 1 139 ? 90.204  108.704 135.659 1.00 27.98 ? 118  ALA D N   1 
ATOM   11495 C CA  . ALA D 1 139 ? 90.860  108.585 134.362 1.00 27.98 ? 118  ALA D CA  1 
ATOM   11496 C C   . ALA D 1 139 ? 92.020  109.566 134.229 1.00 27.98 ? 118  ALA D C   1 
ATOM   11497 O O   . ALA D 1 139 ? 92.141  110.257 133.219 1.00 27.98 ? 118  ALA D O   1 
ATOM   11498 C CB  . ALA D 1 139 ? 89.856  108.799 133.239 1.00 27.98 ? 118  ALA D CB  1 
ATOM   11499 N N   . ASP D 1 140 ? 92.866  109.634 135.257 1.00 29.37 ? 119  ASP D N   1 
ATOM   11500 C CA  . ASP D 1 140 ? 94.068  110.460 135.222 1.00 29.37 ? 119  ASP D CA  1 
ATOM   11501 C C   . ASP D 1 140 ? 95.335  109.614 135.290 1.00 29.37 ? 119  ASP D C   1 
ATOM   11502 O O   . ASP D 1 140 ? 96.205  109.719 134.421 1.00 29.37 ? 119  ASP D O   1 
ATOM   11503 C CB  . ASP D 1 140 ? 94.042  111.481 136.365 1.00 29.37 ? 119  ASP D CB  1 
ATOM   11504 C CG  . ASP D 1 140 ? 93.261  112.731 136.010 1.00 29.37 ? 119  ASP D CG  1 
ATOM   11505 O OD1 . ASP D 1 140 ? 92.551  112.717 134.982 1.00 29.37 ? 119  ASP D OD1 1 
ATOM   11506 O OD2 . ASP D 1 140 ? 93.356  113.726 136.758 1.00 29.37 ? 119  ASP D OD2 1 
ATOM   11507 N N   . LEU D 1 141 ? 95.458  108.781 136.322 1.00 27.93 ? 120  LEU D N   1 
ATOM   11508 C CA  . LEU D 1 141 ? 96.557  107.820 136.367 1.00 27.93 ? 120  LEU D CA  1 
ATOM   11509 C C   . LEU D 1 141 ? 96.572  106.865 135.179 1.00 27.93 ? 120  LEU D C   1 
ATOM   11510 O O   . LEU D 1 141 ? 97.676  106.542 134.704 1.00 27.93 ? 120  LEU D O   1 
ATOM   11511 C CB  . LEU D 1 141 ? 96.519  107.051 137.692 1.00 27.93 ? 120  LEU D CB  1 
ATOM   11512 C CG  . LEU D 1 141 ? 97.280  107.720 138.835 1.00 27.93 ? 120  LEU D CG  1 
ATOM   11513 C CD1 . LEU D 1 141 ? 96.854  107.160 140.185 1.00 27.93 ? 120  LEU D CD1 1 
ATOM   11514 C CD2 . LEU D 1 141 ? 98.774  107.541 138.627 1.00 27.93 ? 120  LEU D CD2 1 
ATOM   11515 N N   . PRO D 1 142 ? 95.439  106.344 134.687 1.00 26.93 ? 121  PRO D N   1 
ATOM   11516 C CA  . PRO D 1 142 ? 95.500  105.534 133.460 1.00 26.93 ? 121  PRO D CA  1 
ATOM   11517 C C   . PRO D 1 142 ? 96.174  106.249 132.305 1.00 26.93 ? 121  PRO D C   1 
ATOM   11518 O O   . PRO D 1 142 ? 97.045  105.668 131.648 1.00 26.93 ? 121  PRO D O   1 
ATOM   11519 C CB  . PRO D 1 142 ? 94.026  105.238 133.168 1.00 26.93 ? 121  PRO D CB  1 
ATOM   11520 C CG  . PRO D 1 142 ? 93.369  105.282 134.474 1.00 26.93 ? 121  PRO D CG  1 
ATOM   11521 C CD  . PRO D 1 142 ? 94.105  106.283 135.310 1.00 26.93 ? 121  PRO D CD  1 
ATOM   11522 N N   . LEU D 1 143 ? 95.823  107.512 132.054 1.00 19.72 ? 122  LEU D N   1 
ATOM   11523 C CA  . LEU D 1 143 ? 96.473  108.230 130.966 1.00 19.72 ? 122  LEU D CA  1 
ATOM   11524 C C   . LEU D 1 143 ? 97.915  108.588 131.295 1.00 19.72 ? 122  LEU D C   1 
ATOM   11525 O O   . LEU D 1 143 ? 98.748  108.621 130.395 1.00 19.72 ? 122  LEU D O   1 
ATOM   11526 C CB  . LEU D 1 143 ? 95.686  109.483 130.595 1.00 19.72 ? 122  LEU D CB  1 
ATOM   11527 C CG  . LEU D 1 143 ? 94.609  109.260 129.535 1.00 19.72 ? 122  LEU D CG  1 
ATOM   11528 C CD1 . LEU D 1 143 ? 93.755  110.502 129.336 1.00 19.72 ? 122  LEU D CD1 1 
ATOM   11529 C CD2 . LEU D 1 143 ? 95.267  108.858 128.229 1.00 19.72 ? 122  LEU D CD2 1 
ATOM   11530 N N   . ALA D 1 144 ? 98.245  108.845 132.560 1.00 18.61 ? 123  ALA D N   1 
ATOM   11531 C CA  . ALA D 1 144 ? 99.639  109.120 132.894 1.00 18.61 ? 123  ALA D CA  1 
ATOM   11532 C C   . ALA D 1 144 ? 100.517 107.915 132.579 1.00 18.61 ? 123  ALA D C   1 
ATOM   11533 O O   . ALA D 1 144 ? 101.545 108.030 131.892 1.00 18.61 ? 123  ALA D O   1 
ATOM   11534 C CB  . ALA D 1 144 ? 99.758  109.507 134.366 1.00 18.61 ? 123  ALA D CB  1 
ATOM   11535 N N   . ILE D 1 145 ? 100.107 106.743 133.061 1.00 16.04 ? 124  ILE D N   1 
ATOM   11536 C CA  . ILE D 1 145 ? 100.821 105.509 132.753 1.00 16.04 ? 124  ILE D CA  1 
ATOM   11537 C C   . ILE D 1 145 ? 100.838 105.276 131.251 1.00 16.04 ? 124  ILE D C   1 
ATOM   11538 O O   . ILE D 1 145 ? 101.856 104.866 130.676 1.00 16.04 ? 124  ILE D O   1 
ATOM   11539 C CB  . ILE D 1 145 ? 100.170 104.334 133.503 1.00 16.04 ? 124  ILE D CB  1 
ATOM   11540 C CG1 . ILE D 1 145 ? 100.267 104.553 135.012 1.00 16.04 ? 124  ILE D CG1 1 
ATOM   11541 C CG2 . ILE D 1 145 ? 100.817 103.025 133.117 1.00 16.04 ? 124  ILE D CG2 1 
ATOM   11542 C CD1 . ILE D 1 145 ? 99.537  103.523 135.828 1.00 16.04 ? 124  ILE D CD1 1 
ATOM   11543 N N   . ASP D 1 146 ? 99.713  105.550 130.591 1.00 15.01 ? 125  ASP D N   1 
ATOM   11544 C CA  . ASP D 1 146 ? 99.595  105.282 129.170 1.00 15.01 ? 125  ASP D CA  1 
ATOM   11545 C C   . ASP D 1 146 ? 100.503 106.188 128.352 1.00 15.01 ? 125  ASP D C   1 
ATOM   11546 O O   . ASP D 1 146 ? 101.050 105.753 127.339 1.00 15.01 ? 125  ASP D O   1 
ATOM   11547 C CB  . ASP D 1 146 ? 98.137  105.446 128.746 1.00 15.01 ? 125  ASP D CB  1 
ATOM   11548 C CG  . ASP D 1 146 ? 97.773  104.581 127.566 1.00 15.01 ? 125  ASP D CG  1 
ATOM   11549 O OD1 . ASP D 1 146 ? 98.644  103.821 127.094 1.00 15.01 ? 125  ASP D OD1 1 
ATOM   11550 O OD2 . ASP D 1 146 ? 96.608  104.648 127.120 1.00 15.01 ? 125  ASP D OD2 1 
ATOM   11551 N N   . HIS D 1 147 ? 100.695 107.439 128.778 1.00 16.03 ? 126  HIS D N   1 
ATOM   11552 C CA  . HIS D 1 147 ? 101.622 108.314 128.067 1.00 16.03 ? 126  HIS D CA  1 
ATOM   11553 C C   . HIS D 1 147 ? 103.064 107.942 128.349 1.00 16.03 ? 126  HIS D C   1 
ATOM   11554 O O   . HIS D 1 147 ? 103.917 108.084 127.470 1.00 16.03 ? 126  HIS D O   1 
ATOM   11555 C CB  . HIS D 1 147 ? 101.388 109.795 128.390 1.00 16.03 ? 126  HIS D CB  1 
ATOM   11556 C CG  . HIS D 1 147 ? 100.067 110.321 127.924 1.00 16.03 ? 126  HIS D CG  1 
ATOM   11557 N ND1 . HIS D 1 147 ? 99.028  110.570 128.795 1.00 16.03 ? 126  HIS D ND1 1 
ATOM   11558 C CD2 . HIS D 1 147 ? 99.579  110.555 126.685 1.00 16.03 ? 126  HIS D CD2 1 
ATOM   11559 C CE1 . HIS D 1 147 ? 97.979  110.998 128.118 1.00 16.03 ? 126  HIS D CE1 1 
ATOM   11560 N NE2 . HIS D 1 147 ? 98.287  110.996 126.834 1.00 16.03 ? 126  HIS D NE2 1 
ATOM   11561 N N   . PHE D 1 148 ? 103.369 107.457 129.551 1.00 12.77 ? 127  PHE D N   1 
ATOM   11562 C CA  . PHE D 1 148 ? 104.721 106.944 129.760 1.00 12.77 ? 127  PHE D CA  1 
ATOM   11563 C C   . PHE D 1 148 ? 105.016 105.795 128.803 1.00 12.77 ? 127  PHE D C   1 
ATOM   11564 O O   . PHE D 1 148 ? 106.048 105.789 128.118 1.00 12.77 ? 127  PHE D O   1 
ATOM   11565 C CB  . PHE D 1 148 ? 104.919 106.517 131.211 1.00 12.77 ? 127  PHE D CB  1 
ATOM   11566 C CG  . PHE D 1 148 ? 105.382 107.627 132.098 1.00 12.77 ? 127  PHE D CG  1 
ATOM   11567 C CD1 . PHE D 1 148 ? 106.690 108.067 132.045 1.00 12.77 ? 127  PHE D CD1 1 
ATOM   11568 C CD2 . PHE D 1 148 ? 104.512 108.240 132.977 1.00 12.77 ? 127  PHE D CD2 1 
ATOM   11569 C CE1 . PHE D 1 148 ? 107.121 109.094 132.851 1.00 12.77 ? 127  PHE D CE1 1 
ATOM   11570 C CE2 . PHE D 1 148 ? 104.938 109.266 133.788 1.00 12.77 ? 127  PHE D CE2 1 
ATOM   11571 C CZ  . PHE D 1 148 ? 106.244 109.693 133.724 1.00 12.77 ? 127  PHE D CZ  1 
ATOM   11572 N N   . ARG D 1 149 ? 104.090 104.837 128.703 1.00 10.96 ? 128  ARG D N   1 
ATOM   11573 C CA  . ARG D 1 149 ? 104.276 103.727 127.771 1.00 10.96 ? 128  ARG D CA  1 
ATOM   11574 C C   . ARG D 1 149 ? 104.316 104.209 126.327 1.00 10.96 ? 128  ARG D C   1 
ATOM   11575 O O   . ARG D 1 149 ? 105.152 103.757 125.536 1.00 10.96 ? 128  ARG D O   1 
ATOM   11576 C CB  . ARG D 1 149 ? 103.167 102.693 127.944 1.00 10.96 ? 128  ARG D CB  1 
ATOM   11577 C CG  . ARG D 1 149 ? 102.894 102.289 129.368 1.00 10.96 ? 128  ARG D CG  1 
ATOM   11578 C CD  . ARG D 1 149 ? 101.704 101.355 129.433 1.00 10.96 ? 128  ARG D CD  1 
ATOM   11579 N NE  . ARG D 1 149 ? 101.501 100.818 130.771 1.00 10.96 ? 128  ARG D NE  1 
ATOM   11580 C CZ  . ARG D 1 149 ? 102.292 99.922  131.344 1.00 10.96 ? 128  ARG D CZ  1 
ATOM   11581 N NH1 . ARG D 1 149 ? 103.347 99.447  130.703 1.00 10.96 ? 128  ARG D NH1 1 
ATOM   11582 N NH2 . ARG D 1 149 ? 102.029 99.498  132.565 1.00 10.96 ? 128  ARG D NH2 1 
ATOM   11583 N N   . TYR D 1 150 ? 103.428 105.135 125.967 1.00 7.13  ? 129  TYR D N   1 
ATOM   11584 C CA  . TYR D 1 150 ? 103.340 105.599 124.590 1.00 7.13  ? 129  TYR D CA  1 
ATOM   11585 C C   . TYR D 1 150 ? 104.598 106.337 124.168 1.00 7.13  ? 129  TYR D C   1 
ATOM   11586 O O   . TYR D 1 150 ? 105.056 106.191 123.033 1.00 7.13  ? 129  TYR D O   1 
ATOM   11587 C CB  . TYR D 1 150 ? 102.123 106.502 124.421 1.00 7.13  ? 129  TYR D CB  1 
ATOM   11588 C CG  . TYR D 1 150 ? 102.072 107.196 123.083 1.00 7.13  ? 129  TYR D CG  1 
ATOM   11589 C CD1 . TYR D 1 150 ? 102.003 106.467 121.905 1.00 7.13  ? 129  TYR D CD1 1 
ATOM   11590 C CD2 . TYR D 1 150 ? 102.101 108.578 122.995 1.00 7.13  ? 129  TYR D CD2 1 
ATOM   11591 C CE1 . TYR D 1 150 ? 101.957 107.092 120.685 1.00 7.13  ? 129  TYR D CE1 1 
ATOM   11592 C CE2 . TYR D 1 150 ? 102.059 109.210 121.775 1.00 7.13  ? 129  TYR D CE2 1 
ATOM   11593 C CZ  . TYR D 1 150 ? 101.988 108.461 120.625 1.00 7.13  ? 129  TYR D CZ  1 
ATOM   11594 O OH  . TYR D 1 150 ? 101.943 109.088 119.405 1.00 7.13  ? 129  TYR D OH  1 
ATOM   11595 N N   . PHE D 1 151 ? 105.165 107.147 125.057 1.00 7.05  ? 130  PHE D N   1 
ATOM   11596 C CA  . PHE D 1 151 ? 106.335 107.918 124.677 1.00 7.05  ? 130  PHE D CA  1 
ATOM   11597 C C   . PHE D 1 151 ? 107.601 107.085 124.733 1.00 7.05  ? 130  PHE D C   1 
ATOM   11598 O O   . PHE D 1 151 ? 108.512 107.313 123.931 1.00 7.05  ? 130  PHE D O   1 
ATOM   11599 C CB  . PHE D 1 151 ? 106.435 109.165 125.543 1.00 7.05  ? 130  PHE D CB  1 
ATOM   11600 C CG  . PHE D 1 151 ? 105.618 110.296 125.020 1.00 7.05  ? 130  PHE D CG  1 
ATOM   11601 C CD1 . PHE D 1 151 ? 105.984 110.943 123.859 1.00 7.05  ? 130  PHE D CD1 1 
ATOM   11602 C CD2 . PHE D 1 151 ? 104.458 110.679 125.659 1.00 7.05  ? 130  PHE D CD2 1 
ATOM   11603 C CE1 . PHE D 1 151 ? 105.226 111.966 123.362 1.00 7.05  ? 130  PHE D CE1 1 
ATOM   11604 C CE2 . PHE D 1 151 ? 103.693 111.705 125.166 1.00 7.05  ? 130  PHE D CE2 1 
ATOM   11605 C CZ  . PHE D 1 151 ? 104.077 112.349 124.016 1.00 7.05  ? 130  PHE D CZ  1 
ATOM   11606 N N   . ALA D 1 152 ? 107.663 106.088 125.619 1.00 6.05  ? 131  ALA D N   1 
ATOM   11607 C CA  . ALA D 1 152 ? 108.679 105.058 125.451 1.00 6.05  ? 131  ALA D CA  1 
ATOM   11608 C C   . ALA D 1 152 ? 108.564 104.413 124.074 1.00 6.05  ? 131  ALA D C   1 
ATOM   11609 O O   . ALA D 1 152 ? 109.575 104.179 123.402 1.00 6.05  ? 131  ALA D O   1 
ATOM   11610 C CB  . ALA D 1 152 ? 108.552 104.010 126.553 1.00 6.05  ? 131  ALA D CB  1 
ATOM   11611 N N   . GLY D 1 153 ? 107.336 104.151 123.624 1.00 4.60  ? 132  GLY D N   1 
ATOM   11612 C CA  . GLY D 1 153 ? 107.150 103.541 122.317 1.00 4.60  ? 132  GLY D CA  1 
ATOM   11613 C C   . GLY D 1 153 ? 107.595 104.428 121.168 1.00 4.60  ? 132  GLY D C   1 
ATOM   11614 O O   . GLY D 1 153 ? 108.258 103.969 120.235 1.00 4.60  ? 132  GLY D O   1 
ATOM   11615 N N   . VAL D 1 154 ? 107.221 105.707 121.210 1.00 4.79  ? 133  VAL D N   1 
ATOM   11616 C CA  . VAL D 1 154 ? 107.626 106.627 120.149 1.00 4.79  ? 133  VAL D CA  1 
ATOM   11617 C C   . VAL D 1 154 ? 109.133 106.844 120.163 1.00 4.79  ? 133  VAL D C   1 
ATOM   11618 O O   . VAL D 1 154 ? 109.750 107.009 119.105 1.00 4.79  ? 133  VAL D O   1 
ATOM   11619 C CB  . VAL D 1 154 ? 106.874 107.966 120.256 1.00 4.79  ? 133  VAL D CB  1 
ATOM   11620 C CG1 . VAL D 1 154 ? 107.193 108.836 119.058 1.00 4.79  ? 133  VAL D CG1 1 
ATOM   11621 C CG2 . VAL D 1 154 ? 105.388 107.737 120.335 1.00 4.79  ? 133  VAL D CG2 1 
ATOM   11622 N N   . LEU D 1 155 ? 109.752 106.864 121.345 1.00 4.78  ? 134  LEU D N   1 
ATOM   11623 C CA  . LEU D 1 155 ? 111.204 106.946 121.414 1.00 4.78  ? 134  LEU D CA  1 
ATOM   11624 C C   . LEU D 1 155 ? 111.852 105.722 120.787 1.00 4.78  ? 134  LEU D C   1 
ATOM   11625 O O   . LEU D 1 155 ? 112.847 105.839 120.063 1.00 4.78  ? 134  LEU D O   1 
ATOM   11626 C CB  . LEU D 1 155 ? 111.646 107.099 122.864 1.00 4.78  ? 134  LEU D CB  1 
ATOM   11627 C CG  . LEU D 1 155 ? 113.148 107.026 123.114 1.00 4.78  ? 134  LEU D CG  1 
ATOM   11628 C CD1 . LEU D 1 155 ? 113.860 108.159 122.396 1.00 4.78  ? 134  LEU D CD1 1 
ATOM   11629 C CD2 . LEU D 1 155 ? 113.419 107.061 124.603 1.00 4.78  ? 134  LEU D CD2 1 
ATOM   11630 N N   . ARG D 1 156 ? 111.305 104.537 121.057 1.00 3.11  ? 135  ARG D N   1 
ATOM   11631 C CA  . ARG D 1 156 ? 111.819 103.332 120.416 1.00 3.11  ? 135  ARG D CA  1 
ATOM   11632 C C   . ARG D 1 156 ? 111.617 103.371 118.910 1.00 3.11  ? 135  ARG D C   1 
ATOM   11633 O O   . ARG D 1 156 ? 112.433 102.828 118.163 1.00 3.11  ? 135  ARG D O   1 
ATOM   11634 C CB  . ARG D 1 156 ? 111.150 102.096 121.014 1.00 3.11  ? 135  ARG D CB  1 
ATOM   11635 C CG  . ARG D 1 156 ? 111.466 101.922 122.473 1.00 3.11  ? 135  ARG D CG  1 
ATOM   11636 C CD  . ARG D 1 156 ? 112.864 101.394 122.648 1.00 3.11  ? 135  ARG D CD  1 
ATOM   11637 N NE  . ARG D 1 156 ? 112.898 99.945  122.761 1.00 3.11  ? 135  ARG D NE  1 
ATOM   11638 C CZ  . ARG D 1 156 ? 113.913 99.199  122.358 1.00 3.11  ? 135  ARG D CZ  1 
ATOM   11639 N NH1 . ARG D 1 156 ? 114.952 99.765  121.771 1.00 3.11  ? 135  ARG D NH1 1 
ATOM   11640 N NH2 . ARG D 1 156 ? 113.875 97.888  122.512 1.00 3.11  ? 135  ARG D NH2 1 
ATOM   11641 N N   . ALA D 1 157 ? 110.542 104.009 118.450 1.00 4.23  ? 136  ALA D N   1 
ATOM   11642 C CA  . ALA D 1 157 ? 110.235 104.057 117.027 1.00 4.23  ? 136  ALA D CA  1 
ATOM   11643 C C   . ALA D 1 157 ? 111.026 105.125 116.280 1.00 4.23  ? 136  ALA D C   1 
ATOM   11644 O O   . ALA D 1 157 ? 111.243 104.988 115.072 1.00 4.23  ? 136  ALA D O   1 
ATOM   11645 C CB  . ALA D 1 157 ? 108.740 104.299 116.835 1.00 4.23  ? 136  ALA D CB  1 
ATOM   11646 N N   . GLN D 1 158 ? 111.454 106.183 116.969 1.00 3.77  ? 137  GLN D N   1 
ATOM   11647 C CA  . GLN D 1 158 ? 112.042 107.348 116.315 1.00 3.77  ? 137  GLN D CA  1 
ATOM   11648 C C   . GLN D 1 158 ? 113.334 106.993 115.596 1.00 3.77  ? 137  GLN D C   1 
ATOM   11649 O O   . GLN D 1 158 ? 114.186 106.283 116.134 1.00 3.77  ? 137  GLN D O   1 
ATOM   11650 C CB  . GLN D 1 158 ? 112.312 108.429 117.353 1.00 3.77  ? 137  GLN D CB  1 
ATOM   11651 C CG  . GLN D 1 158 ? 113.097 109.612 116.849 1.00 3.77  ? 137  GLN D CG  1 
ATOM   11652 C CD  . GLN D 1 158 ? 113.070 110.761 117.821 1.00 3.77  ? 137  GLN D CD  1 
ATOM   11653 O OE1 . GLN D 1 158 ? 113.823 110.784 118.791 1.00 3.77  ? 137  GLN D OE1 1 
ATOM   11654 N NE2 . GLN D 1 158 ? 112.194 111.721 117.575 1.00 3.77  ? 137  GLN D NE2 1 
ATOM   11655 N N   . GLU D 1 159 ? 113.490 107.501 114.372 1.00 2.72  ? 138  GLU D N   1 
ATOM   11656 C CA  . GLU D 1 159 ? 114.637 107.130 113.553 1.00 2.72  ? 138  GLU D CA  1 
ATOM   11657 C C   . GLU D 1 159 ? 115.580 108.290 113.255 1.00 2.72  ? 138  GLU D C   1 
ATOM   11658 O O   . GLU D 1 159 ? 116.726 108.269 113.711 1.00 2.72  ? 138  GLU D O   1 
ATOM   11659 C CB  . GLU D 1 159 ? 114.144 106.514 112.237 1.00 2.72  ? 138  GLU D CB  1 
ATOM   11660 C CG  . GLU D 1 159 ? 113.443 105.170 112.357 1.00 2.72  ? 138  GLU D CG  1 
ATOM   11661 C CD  . GLU D 1 159 ? 114.364 103.988 112.093 1.00 2.72  ? 138  GLU D CD  1 
ATOM   11662 O OE1 . GLU D 1 159 ? 115.365 104.151 111.369 1.00 2.72  ? 138  GLU D OE1 1 
ATOM   11663 O OE2 . GLU D 1 159 ? 114.073 102.882 112.591 1.00 2.72  ? 138  GLU D OE2 1 
ATOM   11664 N N   . GLY D 1 160 ? 115.134 109.324 112.565 1.00 1.72  ? 139  GLY D N   1 
ATOM   11665 C CA  . GLY D 1 160 ? 116.131 110.223 111.992 1.00 1.72  ? 139  GLY D CA  1 
ATOM   11666 C C   . GLY D 1 160 ? 116.448 109.882 110.547 1.00 1.72  ? 139  GLY D C   1 
ATOM   11667 O O   . GLY D 1 160 ? 116.439 108.726 110.132 1.00 1.72  ? 139  GLY D O   1 
ATOM   11668 N N   . SER D 1 161 ? 116.749 110.915 109.766 1.00 1.71  ? 140  SER D N   1 
ATOM   11669 C CA  . SER D 1 161 ? 116.808 110.812 108.315 1.00 1.71  ? 140  SER D CA  1 
ATOM   11670 C C   . SER D 1 161 ? 118.242 110.706 107.816 1.00 1.71  ? 140  SER D C   1 
ATOM   11671 O O   . SER D 1 161 ? 119.187 111.125 108.481 1.00 1.71  ? 140  SER D O   1 
ATOM   11672 C CB  . SER D 1 161 ? 116.134 112.019 107.669 1.00 1.71  ? 140  SER D CB  1 
ATOM   11673 O OG  . SER D 1 161 ? 114.772 112.090 108.035 1.00 1.71  ? 140  SER D OG  1 
ATOM   11674 N N   . ILE D 1 162 ? 118.394 110.133 106.625 1.00 2.14  ? 141  ILE D N   1 
ATOM   11675 C CA  . ILE D 1 162 ? 119.717 109.897 106.061 1.00 2.14  ? 141  ILE D CA  1 
ATOM   11676 C C   . ILE D 1 162 ? 119.775 110.435 104.631 1.00 2.14  ? 141  ILE D C   1 
ATOM   11677 O O   . ILE D 1 162 ? 120.457 109.872 103.767 1.00 2.14  ? 141  ILE D O   1 
ATOM   11678 C CB  . ILE D 1 162 ? 120.097 108.406 106.152 1.00 2.14  ? 141  ILE D CB  1 
ATOM   11679 C CG1 . ILE D 1 162 ? 121.556 108.171 105.819 1.00 2.14  ? 141  ILE D CG1 1 
ATOM   11680 C CG2 . ILE D 1 162 ? 119.365 107.589 105.172 1.00 2.14  ? 141  ILE D CG2 1 
ATOM   11681 C CD1 . ILE D 1 162 ? 121.979 106.827 106.201 1.00 2.14  ? 141  ILE D CD1 1 
ATOM   11682 N N   . SER D 1 163 ? 119.078 111.543 104.379 1.00 3.96  ? 142  SER D N   1 
ATOM   11683 C CA  . SER D 1 163 ? 118.904 112.122 103.048 1.00 3.96  ? 142  SER D CA  1 
ATOM   11684 C C   . SER D 1 163 ? 120.126 111.968 102.158 1.00 3.96  ? 142  SER D C   1 
ATOM   11685 O O   . SER D 1 163 ? 121.206 112.468 102.473 1.00 3.96  ? 142  SER D O   1 
ATOM   11686 C CB  . SER D 1 163 ? 118.593 113.606 103.207 1.00 3.96  ? 142  SER D CB  1 
ATOM   11687 O OG  . SER D 1 163 ? 118.815 114.291 101.993 1.00 3.96  ? 142  SER D OG  1 
ATOM   11688 N N   . GLN D 1 164 ? 119.945 111.301 101.024 1.00 2.18  ? 143  GLN D N   1 
ATOM   11689 C CA  . GLN D 1 164 ? 121.032 111.054 100.084 1.00 2.18  ? 143  GLN D CA  1 
ATOM   11690 C C   . GLN D 1 164 ? 121.026 112.170 99.053  1.00 2.18  ? 143  GLN D C   1 
ATOM   11691 O O   . GLN D 1 164 ? 120.129 112.237 98.209  1.00 2.18  ? 143  GLN D O   1 
ATOM   11692 C CB  . GLN D 1 164 ? 120.877 109.691 99.414  1.00 2.18  ? 143  GLN D CB  1 
ATOM   11693 C CG  . GLN D 1 164 ? 121.270 108.513 100.290 1.00 2.18  ? 143  GLN D CG  1 
ATOM   11694 C CD  . GLN D 1 164 ? 120.374 107.304 100.087 1.00 2.18  ? 143  GLN D CD  1 
ATOM   11695 O OE1 . GLN D 1 164 ? 120.435 106.639 99.056  1.00 2.18  ? 143  GLN D OE1 1 
ATOM   11696 N NE2 . GLN D 1 164 ? 119.520 107.027 101.066 1.00 2.18  ? 143  GLN D NE2 1 
ATOM   11697 N N   . ILE D 1 165 ? 122.019 113.051 99.121  1.00 2.77  ? 144  ILE D N   1 
ATOM   11698 C CA  . ILE D 1 165 ? 122.041 114.169 98.190  1.00 2.77  ? 144  ILE D CA  1 
ATOM   11699 C C   . ILE D 1 165 ? 122.630 113.748 96.859  1.00 2.77  ? 144  ILE D C   1 
ATOM   11700 O O   . ILE D 1 165 ? 122.209 114.236 95.806  1.00 2.77  ? 144  ILE D O   1 
ATOM   11701 C CB  . ILE D 1 165 ? 122.812 115.357 98.784  1.00 2.77  ? 144  ILE D CB  1 
ATOM   11702 C CG1 . ILE D 1 165 ? 122.263 115.717 100.161 1.00 2.77  ? 144  ILE D CG1 1 
ATOM   11703 C CG2 . ILE D 1 165 ? 122.736 116.542 97.858  1.00 2.77  ? 144  ILE D CG2 1 
ATOM   11704 C CD1 . ILE D 1 165 ? 120.844 116.171 100.132 1.00 2.77  ? 144  ILE D CD1 1 
ATOM   11705 N N   . ASP D 1 166 ? 123.587 112.836 96.869  1.00 3.31  ? 145  ASP D N   1 
ATOM   11706 C CA  . ASP D 1 166 ? 124.266 112.450 95.645  1.00 3.31  ? 145  ASP D CA  1 
ATOM   11707 C C   . ASP D 1 166 ? 124.888 111.082 95.881  1.00 3.31  ? 145  ASP D C   1 
ATOM   11708 O O   . ASP D 1 166 ? 124.719 110.479 96.943  1.00 3.31  ? 145  ASP D O   1 
ATOM   11709 C CB  . ASP D 1 166 ? 125.303 113.511 95.258  1.00 3.31  ? 145  ASP D CB  1 
ATOM   11710 C CG  . ASP D 1 166 ? 125.878 113.297 93.876  1.00 3.31  ? 145  ASP D CG  1 
ATOM   11711 O OD1 . ASP D 1 166 ? 125.339 112.450 93.135  1.00 3.31  ? 145  ASP D OD1 1 
ATOM   11712 O OD2 . ASP D 1 166 ? 126.873 113.969 93.536  1.00 3.31  ? 145  ASP D OD2 1 
ATOM   11713 N N   . ASP D 1 167 ? 125.600 110.585 94.871  1.00 3.20  ? 146  ASP D N   1 
ATOM   11714 C CA  . ASP D 1 167 ? 126.427 109.405 95.079  1.00 3.20  ? 146  ASP D CA  1 
ATOM   11715 C C   . ASP D 1 167 ? 127.550 109.692 96.064  1.00 3.20  ? 146  ASP D C   1 
ATOM   11716 O O   . ASP D 1 167 ? 127.979 108.793 96.795  1.00 3.20  ? 146  ASP D O   1 
ATOM   11717 C CB  . ASP D 1 167 ? 126.998 108.925 93.745  1.00 3.20  ? 146  ASP D CB  1 
ATOM   11718 C CG  . ASP D 1 167 ? 127.904 107.722 93.897  1.00 3.20  ? 146  ASP D CG  1 
ATOM   11719 O OD1 . ASP D 1 167 ? 127.436 106.681 94.399  1.00 3.20  ? 146  ASP D OD1 1 
ATOM   11720 O OD2 . ASP D 1 167 ? 129.086 107.818 93.513  1.00 3.20  ? 146  ASP D OD2 1 
ATOM   11721 N N   . ASP D 1 168 ? 128.022 110.939 96.113  1.00 4.78  ? 147  ASP D N   1 
ATOM   11722 C CA  . ASP D 1 168 ? 129.183 111.313 96.910  1.00 4.78  ? 147  ASP D CA  1 
ATOM   11723 C C   . ASP D 1 168 ? 128.851 112.315 98.007  1.00 4.78  ? 147  ASP D C   1 
ATOM   11724 O O   . ASP D 1 168 ? 129.738 113.048 98.443  1.00 4.78  ? 147  ASP D O   1 
ATOM   11725 C CB  . ASP D 1 168 ? 130.275 111.896 96.012  1.00 4.78  ? 147  ASP D CB  1 
ATOM   11726 C CG  . ASP D 1 168 ? 130.675 110.961 94.896  1.00 4.78  ? 147  ASP D CG  1 
ATOM   11727 O OD1 . ASP D 1 168 ? 130.659 109.734 95.115  1.00 4.78  ? 147  ASP D OD1 1 
ATOM   11728 O OD2 . ASP D 1 168 ? 131.009 111.453 93.798  1.00 4.78  ? 147  ASP D OD2 1 
ATOM   11729 N N   . THR D 1 169 ? 127.602 112.379 98.462  1.00 3.87  ? 148  THR D N   1 
ATOM   11730 C CA  . THR D 1 169 ? 127.226 113.373 99.460  1.00 3.87  ? 148  THR D CA  1 
ATOM   11731 C C   . THR D 1 169 ? 125.944 112.932 100.141 1.00 3.87  ? 148  THR D C   1 
ATOM   11732 O O   . THR D 1 169 ? 124.941 112.691 99.465  1.00 3.87  ? 148  THR D O   1 
ATOM   11733 C CB  . THR D 1 169 ? 127.031 114.755 98.828  1.00 3.87  ? 148  THR D CB  1 
ATOM   11734 O OG1 . THR D 1 169 ? 128.289 115.263 98.371  1.00 3.87  ? 148  THR D OG1 1 
ATOM   11735 C CG2 . THR D 1 169 ? 126.449 115.722 99.842  1.00 3.87  ? 148  THR D CG2 1 
ATOM   11736 N N   . VAL D 1 170 ? 125.973 112.846 101.467 1.00 3.16  ? 149  VAL D N   1 
ATOM   11737 C CA  . VAL D 1 170 ? 124.842 112.369 102.252 1.00 3.16  ? 149  VAL D CA  1 
ATOM   11738 C C   . VAL D 1 170 ? 124.608 113.329 103.405 1.00 3.16  ? 149  VAL D C   1 
ATOM   11739 O O   . VAL D 1 170 ? 125.559 113.783 104.044 1.00 3.16  ? 149  VAL D O   1 
ATOM   11740 C CB  . VAL D 1 170 ? 125.079 110.942 102.788 1.00 3.16  ? 149  VAL D CB  1 
ATOM   11741 C CG1 . VAL D 1 170 ? 123.860 110.449 103.535 1.00 3.16  ? 149  VAL D CG1 1 
ATOM   11742 C CG2 . VAL D 1 170 ? 125.399 110.005 101.665 1.00 3.16  ? 149  VAL D CG2 1 
ATOM   11743 N N   . ALA D 1 171 ? 123.349 113.621 103.690 1.00 14.11 ? 150  ALA D N   1 
ATOM   11744 C CA  . ALA D 1 171 ? 122.986 114.450 104.828 1.00 14.11 ? 150  ALA D CA  1 
ATOM   11745 C C   . ALA D 1 171 ? 122.348 113.569 105.888 1.00 14.11 ? 150  ALA D C   1 
ATOM   11746 O O   . ALA D 1 171 ? 121.378 112.863 105.607 1.00 14.11 ? 150  ALA D O   1 
ATOM   11747 C CB  . ALA D 1 171 ? 122.035 115.566 104.411 1.00 14.11 ? 150  ALA D CB  1 
ATOM   11748 N N   . TYR D 1 172 ? 122.889 113.608 107.098 1.00 2.94  ? 151  TYR D N   1 
ATOM   11749 C CA  . TYR D 1 172 ? 122.389 112.824 108.214 1.00 2.94  ? 151  TYR D CA  1 
ATOM   11750 C C   . TYR D 1 172 ? 121.680 113.752 109.183 1.00 2.94  ? 151  TYR D C   1 
ATOM   11751 O O   . TYR D 1 172 ? 122.204 114.814 109.516 1.00 2.94  ? 151  TYR D O   1 
ATOM   11752 C CB  . TYR D 1 172 ? 123.531 112.101 108.924 1.00 2.94  ? 151  TYR D CB  1 
ATOM   11753 C CG  . TYR D 1 172 ? 124.374 111.231 108.029 1.00 2.94  ? 151  TYR D CG  1 
ATOM   11754 C CD1 . TYR D 1 172 ? 123.942 109.981 107.639 1.00 2.94  ? 151  TYR D CD1 1 
ATOM   11755 C CD2 . TYR D 1 172 ? 125.608 111.659 107.583 1.00 2.94  ? 151  TYR D CD2 1 
ATOM   11756 C CE1 . TYR D 1 172 ? 124.708 109.189 106.834 1.00 2.94  ? 151  TYR D CE1 1 
ATOM   11757 C CE2 . TYR D 1 172 ? 126.380 110.871 106.775 1.00 2.94  ? 151  TYR D CE2 1 
ATOM   11758 C CZ  . TYR D 1 172 ? 125.925 109.637 106.404 1.00 2.94  ? 151  TYR D CZ  1 
ATOM   11759 O OH  . TYR D 1 172 ? 126.695 108.843 105.593 1.00 2.94  ? 151  TYR D OH  1 
ATOM   11760 N N   . HIS D 1 173 ? 120.497 113.360 109.637 1.00 1.92  ? 152  HIS D N   1 
ATOM   11761 C CA  . HIS D 1 173 ? 119.683 114.209 110.502 1.00 1.92  ? 152  HIS D CA  1 
ATOM   11762 C C   . HIS D 1 173 ? 119.471 113.500 111.831 1.00 1.92  ? 152  HIS D C   1 
ATOM   11763 O O   . HIS D 1 173 ? 118.477 112.799 112.023 1.00 1.92  ? 152  HIS D O   1 
ATOM   11764 C CB  . HIS D 1 173 ? 118.369 114.552 109.831 1.00 1.92  ? 152  HIS D CB  1 
ATOM   11765 C CG  . HIS D 1 173 ? 118.537 115.229 108.509 1.00 1.92  ? 152  HIS D CG  1 
ATOM   11766 N ND1 . HIS D 1 173 ? 118.746 114.533 107.339 1.00 1.92  ? 152  HIS D ND1 1 
ATOM   11767 C CD2 . HIS D 1 173 ? 118.546 116.538 108.172 1.00 1.92  ? 152  HIS D CD2 1 
ATOM   11768 C CE1 . HIS D 1 173 ? 118.872 115.383 106.338 1.00 1.92  ? 152  HIS D CE1 1 
ATOM   11769 N NE2 . HIS D 1 173 ? 118.756 116.607 106.817 1.00 1.92  ? 152  HIS D NE2 1 
ATOM   11770 N N   . PHE D 1 174 ? 120.402 113.701 112.755 1.00 1.76  ? 153  PHE D N   1 
ATOM   11771 C CA  . PHE D 1 174 ? 120.305 113.111 114.075 1.00 1.76  ? 153  PHE D CA  1 
ATOM   11772 C C   . PHE D 1 174 ? 119.341 113.907 114.947 1.00 1.76  ? 153  PHE D C   1 
ATOM   11773 O O   . PHE D 1 174 ? 118.978 115.046 114.647 1.00 1.76  ? 153  PHE D O   1 
ATOM   11774 C CB  . PHE D 1 174 ? 121.681 113.034 114.722 1.00 1.76  ? 153  PHE D CB  1 
ATOM   11775 C CG  . PHE D 1 174 ? 122.665 112.218 113.944 1.00 1.76  ? 153  PHE D CG  1 
ATOM   11776 C CD1 . PHE D 1 174 ? 123.447 112.798 112.971 1.00 1.76  ? 153  PHE D CD1 1 
ATOM   11777 C CD2 . PHE D 1 174 ? 122.807 110.868 114.190 1.00 1.76  ? 153  PHE D CD2 1 
ATOM   11778 C CE1 . PHE D 1 174 ? 124.344 112.051 112.264 1.00 1.76  ? 153  PHE D CE1 1 
ATOM   11779 C CE2 . PHE D 1 174 ? 123.703 110.122 113.483 1.00 1.76  ? 153  PHE D CE2 1 
ATOM   11780 C CZ  . PHE D 1 174 ? 124.473 110.713 112.518 1.00 1.76  ? 153  PHE D CZ  1 
ATOM   11781 N N   . HIS D 1 175 ? 118.952 113.299 116.062 1.00 3.09  ? 154  HIS D N   1 
ATOM   11782 C CA  . HIS D 1 175 ? 117.893 113.822 116.913 1.00 3.09  ? 154  HIS D CA  1 
ATOM   11783 C C   . HIS D 1 175 ? 118.373 114.150 118.319 1.00 3.09  ? 154  HIS D C   1 
ATOM   11784 O O   . HIS D 1 175 ? 117.772 113.698 119.297 1.00 3.09  ? 154  HIS D O   1 
ATOM   11785 C CB  . HIS D 1 175 ? 116.737 112.833 117.006 1.00 3.09  ? 154  HIS D CB  1 
ATOM   11786 C CG  . HIS D 1 175 ? 115.806 112.863 115.838 1.00 3.09  ? 154  HIS D CG  1 
ATOM   11787 N ND1 . HIS D 1 175 ? 115.025 113.958 115.541 1.00 3.09  ? 154  HIS D ND1 1 
ATOM   11788 C CD2 . HIS D 1 175 ? 115.472 111.909 114.939 1.00 3.09  ? 154  HIS D CD2 1 
ATOM   11789 C CE1 . HIS D 1 175 ? 114.282 113.692 114.484 1.00 3.09  ? 154  HIS D CE1 1 
ATOM   11790 N NE2 . HIS D 1 175 ? 114.532 112.455 114.101 1.00 3.09  ? 154  HIS D NE2 1 
ATOM   11791 N N   . GLU D 1 176 ? 119.458 114.909 118.432 1.00 5.18  ? 155  GLU D N   1 
ATOM   11792 C CA  . GLU D 1 176 ? 120.052 115.316 119.701 1.00 5.18  ? 155  GLU D CA  1 
ATOM   11793 C C   . GLU D 1 176 ? 119.024 115.842 120.693 1.00 5.18  ? 155  GLU D C   1 
ATOM   11794 O O   . GLU D 1 176 ? 117.991 116.387 120.292 1.00 5.18  ? 155  GLU D O   1 
ATOM   11795 C CB  . GLU D 1 176 ? 121.100 116.400 119.461 1.00 5.18  ? 155  GLU D CB  1 
ATOM   11796 C CG  . GLU D 1 176 ? 122.207 115.981 118.544 1.00 5.18  ? 155  GLU D CG  1 
ATOM   11797 C CD  . GLU D 1 176 ? 123.400 116.903 118.618 1.00 5.18  ? 155  GLU D CD  1 
ATOM   11798 O OE1 . GLU D 1 176 ? 124.542 116.398 118.594 1.00 5.18  ? 155  GLU D OE1 1 
ATOM   11799 O OE2 . GLU D 1 176 ? 123.197 118.132 118.699 1.00 5.18  ? 155  GLU D OE2 1 
ATOM   11800 N N   . PRO D 1 177 ? 119.259 115.687 121.989 1.00 5.57  ? 156  PRO D N   1 
ATOM   11801 C CA  . PRO D 1 177 ? 118.408 116.345 122.983 1.00 5.57  ? 156  PRO D CA  1 
ATOM   11802 C C   . PRO D 1 177 ? 118.768 117.815 123.129 1.00 5.57  ? 156  PRO D C   1 
ATOM   11803 O O   . PRO D 1 177 ? 119.893 118.238 122.860 1.00 5.57  ? 156  PRO D O   1 
ATOM   11804 C CB  . PRO D 1 177 ? 118.717 115.583 124.277 1.00 5.57  ? 156  PRO D CB  1 
ATOM   11805 C CG  . PRO D 1 177 ? 119.548 114.400 123.865 1.00 5.57  ? 156  PRO D CG  1 
ATOM   11806 C CD  . PRO D 1 177 ? 120.244 114.800 122.620 1.00 5.57  ? 156  PRO D CD  1 
ATOM   11807 N N   . LEU D 1 178 ? 117.787 118.598 123.575 1.00 6.91  ? 157  LEU D N   1 
ATOM   11808 C CA  . LEU D 1 178 ? 118.040 120.008 123.851 1.00 6.91  ? 157  LEU D CA  1 
ATOM   11809 C C   . LEU D 1 178 ? 119.071 120.170 124.961 1.00 6.91  ? 157  LEU D C   1 
ATOM   11810 O O   . LEU D 1 178 ? 120.155 120.726 124.752 1.00 6.91  ? 157  LEU D O   1 
ATOM   11811 C CB  . LEU D 1 178 ? 116.744 120.718 124.239 1.00 6.91  ? 157  LEU D CB  1 
ATOM   11812 C CG  . LEU D 1 178 ? 115.653 120.963 123.205 1.00 6.91  ? 157  LEU D CG  1 
ATOM   11813 C CD1 . LEU D 1 178 ? 114.383 121.394 123.914 1.00 6.91  ? 157  LEU D CD1 1 
ATOM   11814 C CD2 . LEU D 1 178 ? 116.087 122.010 122.209 1.00 6.91  ? 157  LEU D CD2 1 
ATOM   11815 N N   . GLY D 1 179 ? 118.749 119.680 126.153 1.00 10.24 ? 158  GLY D N   1 
ATOM   11816 C CA  . GLY D 1 179 ? 119.555 119.928 127.329 1.00 10.24 ? 158  GLY D CA  1 
ATOM   11817 C C   . GLY D 1 179 ? 118.694 119.921 128.571 1.00 10.24 ? 158  GLY D C   1 
ATOM   11818 O O   . GLY D 1 179 ? 117.986 118.948 128.836 1.00 10.24 ? 158  GLY D O   1 
ATOM   11819 N N   . VAL D 1 180 ? 118.757 120.986 129.345 1.00 12.59 ? 159  VAL D N   1 
ATOM   11820 C CA  . VAL D 1 180 ? 117.866 121.173 130.481 1.00 12.59 ? 159  VAL D CA  1 
ATOM   11821 C C   . VAL D 1 180 ? 116.635 121.933 130.014 1.00 12.59 ? 159  VAL D C   1 
ATOM   11822 O O   . VAL D 1 180 ? 116.740 122.915 129.271 1.00 12.59 ? 159  VAL D O   1 
ATOM   11823 C CB  . VAL D 1 180 ? 118.582 121.921 131.621 1.00 12.59 ? 159  VAL D CB  1 
ATOM   11824 C CG1 . VAL D 1 180 ? 117.664 122.055 132.816 1.00 12.59 ? 159  VAL D CG1 1 
ATOM   11825 C CG2 . VAL D 1 180 ? 119.865 121.206 131.999 1.00 12.59 ? 159  VAL D CG2 1 
ATOM   11826 N N   . VAL D 1 181 ? 115.458 121.474 130.438 1.00 12.39 ? 160  VAL D N   1 
ATOM   11827 C CA  . VAL D 1 181 ? 114.199 122.146 130.147 1.00 12.39 ? 160  VAL D CA  1 
ATOM   11828 C C   . VAL D 1 181 ? 113.467 122.393 131.459 1.00 12.39 ? 160  VAL D C   1 
ATOM   11829 O O   . VAL D 1 181 ? 113.798 121.827 132.500 1.00 12.39 ? 160  VAL D O   1 
ATOM   11830 C CB  . VAL D 1 181 ? 113.307 121.347 129.173 1.00 12.39 ? 160  VAL D CB  1 
ATOM   11831 C CG1 . VAL D 1 181 ? 114.071 121.002 127.908 1.00 12.39 ? 160  VAL D CG1 1 
ATOM   11832 C CG2 . VAL D 1 181 ? 112.786 120.098 129.838 1.00 12.39 ? 160  VAL D CG2 1 
ATOM   11833 N N   . GLY D 1 182 ? 112.461 123.257 131.396 1.00 17.94 ? 161  GLY D N   1 
ATOM   11834 C CA  . GLY D 1 182 ? 111.673 123.572 132.570 1.00 17.94 ? 161  GLY D CA  1 
ATOM   11835 C C   . GLY D 1 182 ? 110.183 123.608 132.304 1.00 17.94 ? 161  GLY D C   1 
ATOM   11836 O O   . GLY D 1 182 ? 109.735 124.211 131.326 1.00 17.94 ? 161  GLY D O   1 
ATOM   11837 N N   . GLN D 1 183 ? 109.406 122.965 133.167 1.00 23.03 ? 162  GLN D N   1 
ATOM   11838 C CA  . GLN D 1 183 ? 107.956 122.969 133.037 1.00 23.03 ? 162  GLN D CA  1 
ATOM   11839 C C   . GLN D 1 183 ? 107.320 123.729 134.191 1.00 23.03 ? 162  GLN D C   1 
ATOM   11840 O O   . GLN D 1 183 ? 107.842 123.728 135.305 1.00 23.03 ? 162  GLN D O   1 
ATOM   11841 C CB  . GLN D 1 183 ? 107.413 121.540 132.980 1.00 23.03 ? 162  GLN D CB  1 
ATOM   11842 C CG  . GLN D 1 183 ? 105.960 121.446 132.536 1.00 23.03 ? 162  GLN D CG  1 
ATOM   11843 C CD  . GLN D 1 183 ? 105.010 121.088 133.665 1.00 23.03 ? 162  GLN D CD  1 
ATOM   11844 O OE1 . GLN D 1 183 ? 105.380 120.384 134.602 1.00 23.03 ? 162  GLN D OE1 1 
ATOM   11845 N NE2 . GLN D 1 183 ? 103.776 121.570 133.576 1.00 23.03 ? 162  GLN D NE2 1 
ATOM   11846 N N   . PRO D 1 190 ? 96.803  119.031 137.755 1.00 18.67 ? 169  PRO D N   1 
ATOM   11847 C CA  . PRO D 1 190 ? 97.144  117.859 138.563 1.00 18.67 ? 169  PRO D CA  1 
ATOM   11848 C C   . PRO D 1 190 ? 98.406  117.155 138.079 1.00 18.67 ? 169  PRO D C   1 
ATOM   11849 O O   . PRO D 1 190 ? 99.387  117.809 137.736 1.00 18.67 ? 169  PRO D O   1 
ATOM   11850 C CB  . PRO D 1 190 ? 95.922  116.948 138.396 1.00 18.67 ? 169  PRO D CB  1 
ATOM   11851 C CG  . PRO D 1 190 ? 95.135  117.509 137.221 1.00 18.67 ? 169  PRO D CG  1 
ATOM   11852 C CD  . PRO D 1 190 ? 95.878  118.685 136.665 1.00 18.67 ? 169  PRO D CD  1 
ATOM   11853 N N   . LEU D 1 191 ? 98.417  115.819 138.109 1.00 19.20 ? 170  LEU D N   1 
ATOM   11854 C CA  . LEU D 1 191 ? 99.648  115.060 137.743 1.00 19.20 ? 170  LEU D CA  1 
ATOM   11855 C C   . LEU D 1 191 ? 99.588  114.625 136.276 1.00 19.20 ? 170  LEU D C   1 
ATOM   11856 O O   . LEU D 1 191 ? 100.649 114.341 135.700 1.00 19.20 ? 170  LEU D O   1 
ATOM   11857 C CB  . LEU D 1 191 ? 99.788  113.835 138.650 1.00 19.20 ? 170  LEU D CB  1 
ATOM   11858 C CG  . LEU D 1 191 ? 100.978 112.932 138.331 1.00 19.20 ? 170  LEU D CG  1 
ATOM   11859 C CD1 . LEU D 1 191 ? 102.283 113.688 138.506 1.00 19.20 ? 170  LEU D CD1 1 
ATOM   11860 C CD2 . LEU D 1 191 ? 100.965 111.678 139.191 1.00 19.20 ? 170  LEU D CD2 1 
ATOM   11861 N N   . LEU D 1 192 ? 98.385  114.554 135.711 1.00 21.80 ? 171  LEU D N   1 
ATOM   11862 C CA  . LEU D 1 192 ? 98.251  114.138 134.297 1.00 21.80 ? 171  LEU D CA  1 
ATOM   11863 C C   . LEU D 1 192 ? 99.083  115.087 133.424 1.00 21.80 ? 171  LEU D C   1 
ATOM   11864 O O   . LEU D 1 192 ? 99.824  114.581 132.566 1.00 21.80 ? 171  LEU D O   1 
ATOM   11865 C CB  . LEU D 1 192 ? 96.773  114.136 133.901 1.00 21.80 ? 171  LEU D CB  1 
ATOM   11866 C CG  . LEU D 1 192 ? 96.481  113.674 132.475 1.00 21.80 ? 171  LEU D CG  1 
ATOM   11867 C CD1 . LEU D 1 192 ? 95.386  112.620 132.461 1.00 21.80 ? 171  LEU D CD1 1 
ATOM   11868 C CD2 . LEU D 1 192 ? 96.098  114.853 131.595 1.00 21.80 ? 171  LEU D CD2 1 
ATOM   11869 N N   . MET D 1 193 ? 98.968  116.397 133.658 1.00 30.00 ? 172  MET D N   1 
ATOM   11870 C CA  . MET D 1 193 ? 99.741  117.393 132.870 1.00 30.00 ? 172  MET D CA  1 
ATOM   11871 C C   . MET D 1 193 ? 101.226 117.210 133.182 1.00 30.00 ? 172  MET D C   1 
ATOM   11872 O O   . MET D 1 193 ? 102.024 117.145 132.227 1.00 30.00 ? 172  MET D O   1 
ATOM   11873 C CB  . MET D 1 193 ? 99.311  118.818 133.221 1.00 30.00 ? 172  MET D CB  1 
ATOM   11874 C CG  . MET D 1 193 ? 98.192  119.329 132.336 1.00 30.00 ? 172  MET D CG  1 
ATOM   11875 S SD  . MET D 1 193 ? 97.922  118.258 130.898 1.00 30.00 ? 172  MET D SD  1 
ATOM   11876 C CE  . MET D 1 193 ? 99.092  118.963 129.738 1.00 30.00 ? 172  MET D CE  1 
ATOM   11877 N N   . ALA D 1 194 ? 101.574 117.116 134.467 1.00 23.66 ? 173  ALA D N   1 
ATOM   11878 C CA  . ALA D 1 194 ? 102.978 116.852 134.842 1.00 23.66 ? 173  ALA D CA  1 
ATOM   11879 C C   . ALA D 1 194 ? 103.521 115.773 133.912 1.00 23.66 ? 173  ALA D C   1 
ATOM   11880 O O   . ALA D 1 194 ? 104.579 116.003 133.342 1.00 23.66 ? 173  ALA D O   1 
ATOM   11881 C CB  . ALA D 1 194 ? 103.058 116.408 136.277 1.00 23.66 ? 173  ALA D CB  1 
ATOM   11882 N N   . CYS D 1 195 ? 102.787 114.670 133.735 1.00 24.13 ? 174  CYS D N   1 
ATOM   11883 C CA  . CYS D 1 195 ? 103.295 113.527 132.925 1.00 24.13 ? 174  CYS D CA  1 
ATOM   11884 C C   . CYS D 1 195 ? 103.303 113.877 131.434 1.00 24.13 ? 174  CYS D C   1 
ATOM   11885 O O   . CYS D 1 195 ? 104.343 113.665 130.803 1.00 24.13 ? 174  CYS D O   1 
ATOM   11886 C CB  . CYS D 1 195 ? 102.452 112.283 133.165 1.00 24.13 ? 174  CYS D CB  1 
ATOM   11887 S SG  . CYS D 1 195 ? 102.341 111.834 134.917 1.00 24.13 ? 174  CYS D SG  1 
ATOM   11888 N N   . TRP D 1 196 ? 102.197 114.387 130.894 1.00 21.47 ? 175  TRP D N   1 
ATOM   11889 C CA  . TRP D 1 196 ? 102.187 114.826 129.474 1.00 21.47 ? 175  TRP D CA  1 
ATOM   11890 C C   . TRP D 1 196 ? 103.454 115.637 129.192 1.00 21.47 ? 175  TRP D C   1 
ATOM   11891 O O   . TRP D 1 196 ? 103.869 115.674 128.020 1.00 21.47 ? 175  TRP D O   1 
ATOM   11892 C CB  . TRP D 1 196 ? 100.929 115.634 129.132 1.00 21.47 ? 175  TRP D CB  1 
ATOM   11893 C CG  . TRP D 1 196 ? 99.659  114.843 129.134 1.00 21.47 ? 175  TRP D CG  1 
ATOM   11894 C CD1 . TRP D 1 196 ? 99.360  113.766 129.917 1.00 21.47 ? 175  TRP D CD1 1 
ATOM   11895 C CD2 . TRP D 1 196 ? 98.502  115.073 128.311 1.00 21.47 ? 175  TRP D CD2 1 
ATOM   11896 N NE1 . TRP D 1 196 ? 98.100  113.312 129.639 1.00 21.47 ? 175  TRP D NE1 1 
ATOM   11897 C CE2 . TRP D 1 196 ? 97.550  114.090 128.655 1.00 21.47 ? 175  TRP D CE2 1 
ATOM   11898 C CE3 . TRP D 1 196 ? 98.179  116.005 127.320 1.00 21.47 ? 175  TRP D CE3 1 
ATOM   11899 C CZ2 . TRP D 1 196 ? 96.300  114.018 128.042 1.00 21.47 ? 175  TRP D CZ2 1 
ATOM   11900 C CZ3 . TRP D 1 196 ? 96.943  115.934 126.716 1.00 21.47 ? 175  TRP D CZ3 1 
ATOM   11901 C CH2 . TRP D 1 196 ? 96.019  114.953 127.073 1.00 21.47 ? 175  TRP D CH2 1 
ATOM   11902 N N   . LYS D 1 197 ? 104.022 116.288 130.214 1.00 16.33 ? 176  LYS D N   1 
ATOM   11903 C CA  . LYS D 1 197 ? 105.214 117.140 129.944 1.00 16.33 ? 176  LYS D CA  1 
ATOM   11904 C C   . LYS D 1 197 ? 106.501 116.338 130.168 1.00 16.33 ? 176  LYS D C   1 
ATOM   11905 O O   . LYS D 1 197 ? 107.321 116.275 129.237 1.00 16.33 ? 176  LYS D O   1 
ATOM   11906 C CB  . LYS D 1 197 ? 105.186 118.390 130.826 1.00 16.33 ? 176  LYS D CB  1 
ATOM   11907 C CG  . LYS D 1 197 ? 104.325 119.526 130.293 1.00 16.33 ? 176  LYS D CG  1 
ATOM   11908 C CD  . LYS D 1 197 ? 104.111 119.450 128.797 1.00 16.33 ? 176  LYS D CD  1 
ATOM   11909 C CE  . LYS D 1 197 ? 103.989 120.811 128.147 1.00 16.33 ? 176  LYS D CE  1 
ATOM   11910 N NZ  . LYS D 1 197 ? 102.575 121.168 127.884 1.00 16.33 ? 176  LYS D NZ  1 
ATOM   11911 N N   . LEU D 1 198 ? 106.674 115.758 131.357 1.00 15.84 ? 177  LEU D N   1 
ATOM   11912 C CA  . LEU D 1 198 ? 107.901 114.996 131.707 1.00 15.84 ? 177  LEU D CA  1 
ATOM   11913 C C   . LEU D 1 198 ? 108.056 113.808 130.767 1.00 15.84 ? 177  LEU D C   1 
ATOM   11914 O O   . LEU D 1 198 ? 109.186 113.583 130.274 1.00 15.84 ? 177  LEU D O   1 
ATOM   11915 C CB  . LEU D 1 198 ? 107.765 114.505 133.149 1.00 15.84 ? 177  LEU D CB  1 
ATOM   11916 C CG  . LEU D 1 198 ? 108.441 115.372 134.208 1.00 15.84 ? 177  LEU D CG  1 
ATOM   11917 C CD1 . LEU D 1 198 ? 107.562 116.556 134.578 1.00 15.84 ? 177  LEU D CD1 1 
ATOM   11918 C CD2 . LEU D 1 198 ? 108.776 114.550 135.441 1.00 15.84 ? 177  LEU D CD2 1 
ATOM   11919 N N   . ALA D 1 199 ? 106.969 113.074 130.526 1.00 10.84 ? 178  ALA D N   1 
ATOM   11920 C CA  . ALA D 1 199 ? 107.138 111.868 129.719 1.00 10.84 ? 178  ALA D CA  1 
ATOM   11921 C C   . ALA D 1 199 ? 107.819 112.140 128.384 1.00 10.84 ? 178  ALA D C   1 
ATOM   11922 O O   . ALA D 1 199 ? 108.769 111.415 128.049 1.00 10.84 ? 178  ALA D O   1 
ATOM   11923 C CB  . ALA D 1 199 ? 105.786 111.173 129.533 1.00 10.84 ? 178  ALA D CB  1 
ATOM   11924 N N   . PRO D 1 200 ? 107.415 113.135 127.584 1.00 8.80  ? 179  PRO D N   1 
ATOM   11925 C CA  . PRO D 1 200 ? 108.172 113.397 126.349 1.00 8.80  ? 179  PRO D CA  1 
ATOM   11926 C C   . PRO D 1 200 ? 109.588 113.891 126.596 1.00 8.80  ? 179  PRO D C   1 
ATOM   11927 O O   . PRO D 1 200 ? 110.532 113.363 125.992 1.00 8.80  ? 179  PRO D O   1 
ATOM   11928 C CB  . PRO D 1 200 ? 107.321 114.452 125.629 1.00 8.80  ? 179  PRO D CB  1 
ATOM   11929 C CG  . PRO D 1 200 ? 105.991 114.363 126.243 1.00 8.80  ? 179  PRO D CG  1 
ATOM   11930 C CD  . PRO D 1 200 ? 106.205 113.968 127.654 1.00 8.80  ? 179  PRO D CD  1 
ATOM   11931 N N   . ALA D 1 201 ? 109.767 114.886 127.469 1.00 8.78  ? 180  ALA D N   1 
ATOM   11932 C CA  . ALA D 1 201 ? 111.089 115.467 127.678 1.00 8.78  ? 180  ALA D CA  1 
ATOM   11933 C C   . ALA D 1 201 ? 112.086 114.419 128.150 1.00 8.78  ? 180  ALA D C   1 
ATOM   11934 O O   . ALA D 1 201 ? 113.171 114.282 127.576 1.00 8.78  ? 180  ALA D O   1 
ATOM   11935 C CB  . ALA D 1 201 ? 111.006 116.617 128.679 1.00 8.78  ? 180  ALA D CB  1 
ATOM   11936 N N   . ILE D 1 202 ? 111.726 113.653 129.181 1.00 9.13  ? 181  ILE D N   1 
ATOM   11937 C CA  . ILE D 1 202 ? 112.597 112.581 129.656 1.00 9.13  ? 181  ILE D CA  1 
ATOM   11938 C C   . ILE D 1 202 ? 112.859 111.581 128.538 1.00 9.13  ? 181  ILE D C   1 
ATOM   11939 O O   . ILE D 1 202 ? 113.951 111.012 128.434 1.00 9.13  ? 181  ILE D O   1 
ATOM   11940 C CB  . ILE D 1 202 ? 111.978 111.909 130.895 1.00 9.13  ? 181  ILE D CB  1 
ATOM   11941 C CG1 . ILE D 1 202 ? 112.102 112.824 132.109 1.00 9.13  ? 181  ILE D CG1 1 
ATOM   11942 C CG2 . ILE D 1 202 ? 112.635 110.572 131.184 1.00 9.13  ? 181  ILE D CG2 1 
ATOM   11943 C CD1 . ILE D 1 202 ? 111.307 112.351 133.303 1.00 9.13  ? 181  ILE D CD1 1 
ATOM   11944 N N   . ALA D 1 203 ? 111.867 111.369 127.672 1.00 7.86  ? 182  ALA D N   1 
ATOM   11945 C CA  . ALA D 1 203 ? 112.063 110.498 126.523 1.00 7.86  ? 182  ALA D CA  1 
ATOM   11946 C C   . ALA D 1 203 ? 113.147 111.039 125.604 1.00 7.86  ? 182  ALA D C   1 
ATOM   11947 O O   . ALA D 1 203 ? 113.980 110.280 125.099 1.00 7.86  ? 182  ALA D O   1 
ATOM   11948 C CB  . ALA D 1 203 ? 110.754 110.340 125.758 1.00 7.86  ? 182  ALA D CB  1 
ATOM   11949 N N   . ALA D 1 204 ? 113.158 112.353 125.381 1.00 6.38  ? 183  ALA D N   1 
ATOM   11950 C CA  . ALA D 1 204 ? 114.104 112.926 124.435 1.00 6.38  ? 183  ALA D CA  1 
ATOM   11951 C C   . ALA D 1 204 ? 115.517 112.991 124.989 1.00 6.38  ? 183  ALA D C   1 
ATOM   11952 O O   . ALA D 1 204 ? 116.461 113.161 124.213 1.00 6.38  ? 183  ALA D O   1 
ATOM   11953 C CB  . ALA D 1 204 ? 113.645 114.317 124.016 1.00 6.38  ? 183  ALA D CB  1 
ATOM   11954 N N   . GLY D 1 205 ? 115.685 112.859 126.300 1.00 7.11  ? 184  GLY D N   1 
ATOM   11955 C CA  . GLY D 1 205 ? 117.000 112.920 126.899 1.00 7.11  ? 184  GLY D CA  1 
ATOM   11956 C C   . GLY D 1 205 ? 117.286 114.258 127.542 1.00 7.11  ? 184  GLY D C   1 
ATOM   11957 O O   . GLY D 1 205 ? 118.388 114.794 127.405 1.00 7.11  ? 184  GLY D O   1 
ATOM   11958 N N   . ASN D 1 206 ? 116.304 114.808 128.248 1.00 8.28  ? 185  ASN D N   1 
ATOM   11959 C CA  . ASN D 1 206 ? 116.407 116.126 128.858 1.00 8.28  ? 185  ASN D CA  1 
ATOM   11960 C C   . ASN D 1 206 ? 116.220 116.014 130.361 1.00 8.28  ? 185  ASN D C   1 
ATOM   11961 O O   . ASN D 1 206 ? 115.307 115.324 130.826 1.00 8.28  ? 185  ASN D O   1 
ATOM   11962 C CB  . ASN D 1 206 ? 115.368 117.085 128.280 1.00 8.28  ? 185  ASN D CB  1 
ATOM   11963 C CG  . ASN D 1 206 ? 115.470 117.211 126.787 1.00 8.28  ? 185  ASN D CG  1 
ATOM   11964 O OD1 . ASN D 1 206 ? 116.514 116.949 126.205 1.00 8.28  ? 185  ASN D OD1 1 
ATOM   11965 N ND2 . ASN D 1 206 ? 114.388 117.619 126.155 1.00 8.28  ? 185  ASN D ND2 1 
ATOM   11966 N N   . CYS D 1 207 ? 117.075 116.700 131.113 1.00 12.48 ? 186  CYS D N   1 
ATOM   11967 C CA  . CYS D 1 207 ? 116.975 116.736 132.570 1.00 12.48 ? 186  CYS D CA  1 
ATOM   11968 C C   . CYS D 1 207 ? 116.049 117.880 132.945 1.00 12.48 ? 186  CYS D C   1 
ATOM   11969 O O   . CYS D 1 207 ? 116.445 119.045 132.924 1.00 12.48 ? 186  CYS D O   1 
ATOM   11970 C CB  . CYS D 1 207 ? 118.351 116.895 133.200 1.00 12.48 ? 186  CYS D CB  1 
ATOM   11971 S SG  . CYS D 1 207 ? 119.563 115.726 132.572 1.00 12.48 ? 186  CYS D SG  1 
ATOM   11972 N N   . VAL D 1 208 ? 114.811 117.547 133.299 1.00 11.33 ? 187  VAL D N   1 
ATOM   11973 C CA  . VAL D 1 208 ? 113.783 118.548 133.558 1.00 11.33 ? 187  VAL D CA  1 
ATOM   11974 C C   . VAL D 1 208 ? 114.039 119.240 134.886 1.00 11.33 ? 187  VAL D C   1 
ATOM   11975 O O   . VAL D 1 208 ? 114.841 118.775 135.701 1.00 11.33 ? 187  VAL D O   1 
ATOM   11976 C CB  . VAL D 1 208 ? 112.381 117.919 133.547 1.00 11.33 ? 187  VAL D CB  1 
ATOM   11977 C CG1 . VAL D 1 208 ? 112.035 117.427 132.159 1.00 11.33 ? 187  VAL D CG1 1 
ATOM   11978 C CG2 . VAL D 1 208 ? 112.310 116.793 134.551 1.00 11.33 ? 187  VAL D CG2 1 
ATOM   11979 N N   . VAL D 1 209 ? 113.364 120.365 135.101 1.00 12.22 ? 188  VAL D N   1 
ATOM   11980 C CA  . VAL D 1 209 ? 113.329 121.043 136.391 1.00 12.22 ? 188  VAL D CA  1 
ATOM   11981 C C   . VAL D 1 209 ? 111.888 121.447 136.659 1.00 12.22 ? 188  VAL D C   1 
ATOM   11982 O O   . VAL D 1 209 ? 111.265 122.119 135.831 1.00 12.22 ? 188  VAL D O   1 
ATOM   11983 C CB  . VAL D 1 209 ? 114.256 122.273 136.424 1.00 12.22 ? 188  VAL D CB  1 
ATOM   11984 C CG1 . VAL D 1 209 ? 113.909 123.164 137.598 1.00 12.22 ? 188  VAL D CG1 1 
ATOM   11985 C CG2 . VAL D 1 209 ? 115.706 121.837 136.498 1.00 12.22 ? 188  VAL D CG2 1 
ATOM   11986 N N   . LEU D 1 210 ? 111.356 121.039 137.805 1.00 13.98 ? 189  LEU D N   1 
ATOM   11987 C CA  . LEU D 1 210 ? 109.953 121.290 138.113 1.00 13.98 ? 189  LEU D CA  1 
ATOM   11988 C C   . LEU D 1 210 ? 109.780 122.348 139.188 1.00 13.98 ? 189  LEU D C   1 
ATOM   11989 O O   . LEU D 1 210 ? 108.682 122.869 139.377 1.00 13.98 ? 189  LEU D O   1 
ATOM   11990 C CB  . LEU D 1 210 ? 109.256 119.999 138.546 1.00 13.98 ? 189  LEU D CB  1 
ATOM   11991 C CG  . LEU D 1 210 ? 108.742 119.056 137.453 1.00 13.98 ? 189  LEU D CG  1 
ATOM   11992 C CD1 . LEU D 1 210 ? 107.656 119.744 136.653 1.00 13.98 ? 189  LEU D CD1 1 
ATOM   11993 C CD2 . LEU D 1 210 ? 109.847 118.565 136.535 1.00 13.98 ? 189  LEU D CD2 1 
ATOM   11994 N N   . ILE D 1 220 ? 101.802 115.292 142.875 1.00 22.85 ? 199  ILE D N   1 
ATOM   11995 C CA  . ILE D 1 220 ? 103.080 115.343 142.178 1.00 22.85 ? 199  ILE D CA  1 
ATOM   11996 C C   . ILE D 1 220 ? 104.217 114.990 143.128 1.00 22.85 ? 199  ILE D C   1 
ATOM   11997 O O   . ILE D 1 220 ? 105.129 114.254 142.762 1.00 22.85 ? 199  ILE D O   1 
ATOM   11998 C CB  . ILE D 1 220 ? 103.309 116.719 141.543 1.00 22.85 ? 199  ILE D CB  1 
ATOM   11999 C CG1 . ILE D 1 220 ? 102.179 117.044 140.568 1.00 22.85 ? 199  ILE D CG1 1 
ATOM   12000 C CG2 . ILE D 1 220 ? 104.653 116.764 140.837 1.00 22.85 ? 199  ILE D CG2 1 
ATOM   12001 C CD1 . ILE D 1 220 ? 102.464 118.225 139.667 1.00 22.85 ? 199  ILE D CD1 1 
ATOM   12002 N N   . MET D 1 221 ? 104.154 115.515 144.353 1.00 25.91 ? 200  MET D N   1 
ATOM   12003 C CA  . MET D 1 221 ? 105.209 115.254 145.329 1.00 25.91 ? 200  MET D CA  1 
ATOM   12004 C C   . MET D 1 221 ? 105.293 113.769 145.670 1.00 25.91 ? 200  MET D C   1 
ATOM   12005 O O   . MET D 1 221 ? 106.367 113.159 145.577 1.00 25.91 ? 200  MET D O   1 
ATOM   12006 C CB  . MET D 1 221 ? 104.973 116.087 146.590 1.00 25.91 ? 200  MET D CB  1 
ATOM   12007 C CG  . MET D 1 221 ? 105.605 117.477 146.565 1.00 25.91 ? 200  MET D CG  1 
ATOM   12008 S SD  . MET D 1 221 ? 104.740 118.678 145.530 1.00 25.91 ? 200  MET D SD  1 
ATOM   12009 C CE  . MET D 1 221 ? 103.102 118.665 146.254 1.00 25.91 ? 200  MET D CE  1 
ATOM   12010 N N   . VAL D 1 222 ? 104.162 113.166 146.047 1.00 24.02 ? 201  VAL D N   1 
ATOM   12011 C CA  . VAL D 1 222 ? 104.153 111.751 146.417 1.00 24.02 ? 201  VAL D CA  1 
ATOM   12012 C C   . VAL D 1 222 ? 104.604 110.893 145.244 1.00 24.02 ? 201  VAL D C   1 
ATOM   12013 O O   . VAL D 1 222 ? 105.389 109.950 145.405 1.00 24.02 ? 201  VAL D O   1 
ATOM   12014 C CB  . VAL D 1 222 ? 102.756 111.336 146.913 1.00 24.02 ? 201  VAL D CB  1 
ATOM   12015 C CG1 . VAL D 1 222 ? 102.691 109.832 147.112 1.00 24.02 ? 201  VAL D CG1 1 
ATOM   12016 C CG2 . VAL D 1 222 ? 102.404 112.066 148.205 1.00 24.02 ? 201  VAL D CG2 1 
ATOM   12017 N N   . TRP D 1 223 ? 104.112 111.206 144.046 1.00 23.72 ? 202  TRP D N   1 
ATOM   12018 C CA  . TRP D 1 223 ? 104.561 110.513 142.846 1.00 23.72 ? 202  TRP D CA  1 
ATOM   12019 C C   . TRP D 1 223 ? 106.043 110.749 142.595 1.00 23.72 ? 202  TRP D C   1 
ATOM   12020 O O   . TRP D 1 223 ? 106.766 109.828 142.203 1.00 23.72 ? 202  TRP D O   1 
ATOM   12021 C CB  . TRP D 1 223 ? 103.722 110.970 141.657 1.00 23.72 ? 202  TRP D CB  1 
ATOM   12022 C CG  . TRP D 1 223 ? 104.360 110.791 140.331 1.00 23.72 ? 202  TRP D CG  1 
ATOM   12023 C CD1 . TRP D 1 223 ? 104.449 109.640 139.610 1.00 23.72 ? 202  TRP D CD1 1 
ATOM   12024 C CD2 . TRP D 1 223 ? 104.988 111.806 139.548 1.00 23.72 ? 202  TRP D CD2 1 
ATOM   12025 N NE1 . TRP D 1 223 ? 105.097 109.875 138.422 1.00 23.72 ? 202  TRP D NE1 1 
ATOM   12026 C CE2 . TRP D 1 223 ? 105.439 111.201 138.362 1.00 23.72 ? 202  TRP D CE2 1 
ATOM   12027 C CE3 . TRP D 1 223 ? 105.217 113.170 139.737 1.00 23.72 ? 202  TRP D CE3 1 
ATOM   12028 C CZ2 . TRP D 1 223 ? 106.101 111.914 137.369 1.00 23.72 ? 202  TRP D CZ2 1 
ATOM   12029 C CZ3 . TRP D 1 223 ? 105.875 113.875 138.749 1.00 23.72 ? 202  TRP D CZ3 1 
ATOM   12030 C CH2 . TRP D 1 223 ? 106.311 113.246 137.584 1.00 23.72 ? 202  TRP D CH2 1 
ATOM   12031 N N   . ALA D 1 224 ? 106.515 111.978 142.818 1.00 21.77 ? 203  ALA D N   1 
ATOM   12032 C CA  . ALA D 1 224 ? 107.934 112.265 142.635 1.00 21.77 ? 203  ALA D CA  1 
ATOM   12033 C C   . ALA D 1 224 ? 108.799 111.457 143.588 1.00 21.77 ? 203  ALA D C   1 
ATOM   12034 O O   . ALA D 1 224 ? 109.974 111.207 143.295 1.00 21.77 ? 203  ALA D O   1 
ATOM   12035 C CB  . ALA D 1 224 ? 108.206 113.757 142.818 1.00 21.77 ? 203  ALA D CB  1 
ATOM   12036 N N   . ASN D 1 225 ? 108.245 111.043 144.729 1.00 24.95 ? 204  ASN D N   1 
ATOM   12037 C CA  . ASN D 1 225 ? 109.044 110.275 145.681 1.00 24.95 ? 204  ASN D CA  1 
ATOM   12038 C C   . ASN D 1 225 ? 109.411 108.899 145.132 1.00 24.95 ? 204  ASN D C   1 
ATOM   12039 O O   . ASN D 1 225 ? 110.542 108.436 145.321 1.00 24.95 ? 204  ASN D O   1 
ATOM   12040 C CB  . ASN D 1 225 ? 108.308 110.142 147.013 1.00 24.95 ? 204  ASN D CB  1 
ATOM   12041 C CG  . ASN D 1 225 ? 108.092 111.476 147.692 1.00 24.95 ? 204  ASN D CG  1 
ATOM   12042 O OD1 . ASN D 1 225 ? 106.962 111.922 147.858 1.00 24.95 ? 204  ASN D OD1 1 
ATOM   12043 N ND2 . ASN D 1 225 ? 109.183 112.134 148.065 1.00 24.95 ? 204  ASN D ND2 1 
ATOM   12044 N N   . LEU D 1 226 ? 108.478 108.226 144.452 1.00 22.63 ? 205  LEU D N   1 
ATOM   12045 C CA  . LEU D 1 226 ? 108.781 106.893 143.936 1.00 22.63 ? 205  LEU D CA  1 
ATOM   12046 C C   . LEU D 1 226 ? 109.438 106.950 142.561 1.00 22.63 ? 205  LEU D C   1 
ATOM   12047 O O   . LEU D 1 226 ? 110.325 106.141 142.265 1.00 22.63 ? 205  LEU D O   1 
ATOM   12048 C CB  . LEU D 1 226 ? 107.515 106.031 143.896 1.00 22.63 ? 205  LEU D CB  1 
ATOM   12049 C CG  . LEU D 1 226 ? 106.307 106.414 143.038 1.00 22.63 ? 205  LEU D CG  1 
ATOM   12050 C CD1 . LEU D 1 226 ? 106.437 105.892 141.615 1.00 22.63 ? 205  LEU D CD1 1 
ATOM   12051 C CD2 . LEU D 1 226 ? 105.035 105.886 143.671 1.00 22.63 ? 205  LEU D CD2 1 
ATOM   12052 N N   . ILE D 1 227 ? 109.022 107.888 141.708 1.00 20.54 ? 206  ILE D N   1 
ATOM   12053 C CA  . ILE D 1 227 ? 109.600 107.974 140.371 1.00 20.54 ? 206  ILE D CA  1 
ATOM   12054 C C   . ILE D 1 227 ? 111.060 108.407 140.435 1.00 20.54 ? 206  ILE D C   1 
ATOM   12055 O O   . ILE D 1 227 ? 111.881 107.982 139.613 1.00 20.54 ? 206  ILE D O   1 
ATOM   12056 C CB  . ILE D 1 227 ? 108.773 108.916 139.476 1.00 20.54 ? 206  ILE D CB  1 
ATOM   12057 C CG1 . ILE D 1 227 ? 109.233 108.805 138.025 1.00 20.54 ? 206  ILE D CG1 1 
ATOM   12058 C CG2 . ILE D 1 227 ? 108.908 110.342 139.911 1.00 20.54 ? 206  ILE D CG2 1 
ATOM   12059 C CD1 . ILE D 1 227 ? 108.296 109.440 137.046 1.00 20.54 ? 206  ILE D CD1 1 
ATOM   12060 N N   . GLY D 1 228 ? 111.408 109.254 141.406 1.00 19.45 ? 207  GLY D N   1 
ATOM   12061 C CA  . GLY D 1 228 ? 112.707 109.905 141.379 1.00 19.45 ? 207  GLY D CA  1 
ATOM   12062 C C   . GLY D 1 228 ? 113.868 108.932 141.411 1.00 19.45 ? 207  GLY D C   1 
ATOM   12063 O O   . GLY D 1 228 ? 114.876 109.135 140.730 1.00 19.45 ? 207  GLY D O   1 
ATOM   12064 N N   . ASP D 1 229 ? 113.743 107.861 142.196 1.00 22.17 ? 208  ASP D N   1 
ATOM   12065 C CA  . ASP D 1 229 ? 114.862 106.941 142.369 1.00 22.17 ? 208  ASP D CA  1 
ATOM   12066 C C   . ASP D 1 229 ? 115.144 106.159 141.094 1.00 22.17 ? 208  ASP D C   1 
ATOM   12067 O O   . ASP D 1 229 ? 116.295 105.800 140.822 1.00 22.17 ? 208  ASP D O   1 
ATOM   12068 C CB  . ASP D 1 229 ? 114.581 105.994 143.532 1.00 22.17 ? 208  ASP D CB  1 
ATOM   12069 C CG  . ASP D 1 229 ? 114.309 106.732 144.827 1.00 22.17 ? 208  ASP D CG  1 
ATOM   12070 O OD1 . ASP D 1 229 ? 113.137 107.090 145.070 1.00 22.17 ? 208  ASP D OD1 1 
ATOM   12071 O OD2 . ASP D 1 229 ? 115.266 106.959 145.599 1.00 22.17 ? 208  ASP D OD2 1 
ATOM   12072 N N   . LEU D 1 230 ? 114.105 105.875 140.305 1.00 18.52 ? 209  LEU D N   1 
ATOM   12073 C CA  . LEU D 1 230 ? 114.311 105.161 139.050 1.00 18.52 ? 209  LEU D CA  1 
ATOM   12074 C C   . LEU D 1 230 ? 115.185 105.961 138.093 1.00 18.52 ? 209  LEU D C   1 
ATOM   12075 O O   . LEU D 1 230 ? 116.076 105.404 137.440 1.00 18.52 ? 209  LEU D O   1 
ATOM   12076 C CB  . LEU D 1 230 ? 112.969 104.828 138.402 1.00 18.52 ? 209  LEU D CB  1 
ATOM   12077 C CG  . LEU D 1 230 ? 112.232 103.635 139.002 1.00 18.52 ? 209  LEU D CG  1 
ATOM   12078 C CD1 . LEU D 1 230 ? 110.883 103.456 138.346 1.00 18.52 ? 209  LEU D CD1 1 
ATOM   12079 C CD2 . LEU D 1 230 ? 113.067 102.381 138.843 1.00 18.52 ? 209  LEU D CD2 1 
ATOM   12080 N N   . LEU D 1 231 ? 114.944 107.257 137.993 1.00 14.28 ? 210  LEU D N   1 
ATOM   12081 C CA  . LEU D 1 231 ? 115.778 108.104 137.155 1.00 14.28 ? 210  LEU D CA  1 
ATOM   12082 C C   . LEU D 1 231 ? 117.115 108.370 137.842 1.00 14.28 ? 210  LEU D C   1 
ATOM   12083 O O   . LEU D 1 231 ? 117.168 108.493 139.069 1.00 14.28 ? 210  LEU D O   1 
ATOM   12084 C CB  . LEU D 1 231 ? 115.075 109.426 136.867 1.00 14.28 ? 210  LEU D CB  1 
ATOM   12085 C CG  . LEU D 1 231 ? 113.811 109.339 136.015 1.00 14.28 ? 210  LEU D CG  1 
ATOM   12086 C CD1 . LEU D 1 231 ? 112.977 110.595 136.177 1.00 14.28 ? 210  LEU D CD1 1 
ATOM   12087 C CD2 . LEU D 1 231 ? 114.167 109.107 134.557 1.00 14.28 ? 210  LEU D CD2 1 
ATOM   12088 N N   . PRO D 1 232 ? 118.204 108.447 137.084 1.00 13.30 ? 211  PRO D N   1 
ATOM   12089 C CA  . PRO D 1 232 ? 119.485 108.866 137.658 1.00 13.30 ? 211  PRO D CA  1 
ATOM   12090 C C   . PRO D 1 232 ? 119.374 110.259 138.247 1.00 13.30 ? 211  PRO D C   1 
ATOM   12091 O O   . PRO D 1 232 ? 118.624 111.097 137.726 1.00 13.30 ? 211  PRO D O   1 
ATOM   12092 C CB  . PRO D 1 232 ? 120.434 108.843 136.454 1.00 13.30 ? 211  PRO D CB  1 
ATOM   12093 C CG  . PRO D 1 232 ? 119.826 107.849 135.523 1.00 13.30 ? 211  PRO D CG  1 
ATOM   12094 C CD  . PRO D 1 232 ? 118.342 107.977 135.697 1.00 13.30 ? 211  PRO D CD  1 
ATOM   12095 N N   . PRO D 1 233 ? 120.089 110.542 139.336 1.00 12.58 ? 212  PRO D N   1 
ATOM   12096 C CA  . PRO D 1 233 ? 119.921 111.829 140.020 1.00 12.58 ? 212  PRO D CA  1 
ATOM   12097 C C   . PRO D 1 233 ? 120.293 113.002 139.125 1.00 12.58 ? 212  PRO D C   1 
ATOM   12098 O O   . PRO D 1 233 ? 121.251 112.944 138.351 1.00 12.58 ? 212  PRO D O   1 
ATOM   12099 C CB  . PRO D 1 233 ? 120.874 111.695 141.218 1.00 12.58 ? 212  PRO D CB  1 
ATOM   12100 C CG  . PRO D 1 233 ? 121.015 110.173 141.326 1.00 12.58 ? 212  PRO D CG  1 
ATOM   12101 C CD  . PRO D 1 233 ? 121.272 109.888 139.902 1.00 12.58 ? 212  PRO D CD  1 
ATOM   12102 N N   . GLY D 1 234 ? 119.520 114.077 139.240 1.00 12.69 ? 213  GLY D N   1 
ATOM   12103 C CA  . GLY D 1 234 ? 119.700 115.252 138.426 1.00 12.69 ? 213  GLY D CA  1 
ATOM   12104 C C   . GLY D 1 234 ? 118.815 115.319 137.202 1.00 12.69 ? 213  GLY D C   1 
ATOM   12105 O O   . GLY D 1 234 ? 118.652 116.402 136.632 1.00 12.69 ? 213  GLY D O   1 
ATOM   12106 N N   . VAL D 1 235 ? 118.239 114.193 136.781 1.00 11.89 ? 214  VAL D N   1 
ATOM   12107 C CA  . VAL D 1 235 ? 117.348 114.198 135.627 1.00 11.89 ? 214  VAL D CA  1 
ATOM   12108 C C   . VAL D 1 235 ? 116.016 114.843 135.984 1.00 11.89 ? 214  VAL D C   1 
ATOM   12109 O O   . VAL D 1 235 ? 115.526 115.726 135.273 1.00 11.89 ? 214  VAL D O   1 
ATOM   12110 C CB  . VAL D 1 235 ? 117.158 112.768 135.095 1.00 11.89 ? 214  VAL D CB  1 
ATOM   12111 C CG1 . VAL D 1 235 ? 116.075 112.738 134.038 1.00 11.89 ? 214  VAL D CG1 1 
ATOM   12112 C CG2 . VAL D 1 235 ? 118.467 112.240 134.541 1.00 11.89 ? 214  VAL D CG2 1 
ATOM   12113 N N   . LEU D 1 236 ? 115.413 114.422 137.090 1.00 12.84 ? 215  LEU D N   1 
ATOM   12114 C CA  . LEU D 1 236 ? 114.143 114.966 137.549 1.00 12.84 ? 215  LEU D CA  1 
ATOM   12115 C C   . LEU D 1 236 ? 114.374 115.756 138.829 1.00 12.84 ? 215  LEU D C   1 
ATOM   12116 O O   . LEU D 1 236 ? 115.041 115.273 139.748 1.00 12.84 ? 215  LEU D O   1 
ATOM   12117 C CB  . LEU D 1 236 ? 113.119 113.856 137.787 1.00 12.84 ? 215  LEU D CB  1 
ATOM   12118 C CG  . LEU D 1 236 ? 111.850 114.258 138.546 1.00 12.84 ? 215  LEU D CG  1 
ATOM   12119 C CD1 . LEU D 1 236 ? 111.100 115.358 137.814 1.00 12.84 ? 215  LEU D CD1 1 
ATOM   12120 C CD2 . LEU D 1 236 ? 110.951 113.064 138.775 1.00 12.84 ? 215  LEU D CD2 1 
ATOM   12121 N N   . ASN D 1 237 ? 113.821 116.962 138.886 1.00 13.42 ? 216  ASN D N   1 
ATOM   12122 C CA  . ASN D 1 237 ? 114.032 117.838 140.028 1.00 13.42 ? 216  ASN D CA  1 
ATOM   12123 C C   . ASN D 1 237 ? 112.732 118.491 140.487 1.00 13.42 ? 216  ASN D C   1 
ATOM   12124 O O   . ASN D 1 237 ? 112.389 119.589 140.053 1.00 13.42 ? 216  ASN D O   1 
ATOM   12125 C CB  . ASN D 1 237 ? 115.068 118.903 139.681 1.00 13.42 ? 216  ASN D CB  1 
ATOM   12126 C CG  . ASN D 1 237 ? 116.402 118.305 139.296 1.00 13.42 ? 216  ASN D CG  1 
ATOM   12127 O OD1 . ASN D 1 237 ? 116.879 117.370 139.932 1.00 13.42 ? 216  ASN D OD1 1 
ATOM   12128 N ND2 . ASN D 1 237 ? 117.011 118.839 138.246 1.00 13.42 ? 216  ASN D ND2 1 
ATOM   12129 N N   . SER D 1 290 ? 84.286  126.382 122.257 1.00 16.49 ? 269  SER D N   1 
ATOM   12130 C CA  . SER D 1 290 ? 84.119  125.214 121.402 1.00 16.49 ? 269  SER D CA  1 
ATOM   12131 C C   . SER D 1 290 ? 82.649  124.914 121.143 1.00 16.49 ? 269  SER D C   1 
ATOM   12132 O O   . SER D 1 290 ? 81.985  124.314 121.983 1.00 16.49 ? 269  SER D O   1 
ATOM   12133 C CB  . SER D 1 290 ? 84.789  123.993 122.030 1.00 16.49 ? 269  SER D CB  1 
ATOM   12134 O OG  . SER D 1 290 ? 84.605  122.843 121.225 1.00 16.49 ? 269  SER D OG  1 
ATOM   12135 N N   . PRO D 1 291 ? 82.144  125.320 119.979 1.00 17.18 ? 270  PRO D N   1 
ATOM   12136 C CA  . PRO D 1 291 ? 80.755  125.006 119.635 1.00 17.18 ? 270  PRO D CA  1 
ATOM   12137 C C   . PRO D 1 291 ? 80.525  123.504 119.615 1.00 17.18 ? 270  PRO D C   1 
ATOM   12138 O O   . PRO D 1 291 ? 81.458  122.703 119.532 1.00 17.18 ? 270  PRO D O   1 
ATOM   12139 C CB  . PRO D 1 291 ? 80.581  125.622 118.243 1.00 17.18 ? 270  PRO D CB  1 
ATOM   12140 C CG  . PRO D 1 291 ? 81.973  125.787 117.720 1.00 17.18 ? 270  PRO D CG  1 
ATOM   12141 C CD  . PRO D 1 291 ? 82.820  126.079 118.917 1.00 17.18 ? 270  PRO D CD  1 
ATOM   12142 N N   . ASN D 1 292 ? 79.257  123.120 119.712 1.00 19.65 ? 271  ASN D N   1 
ATOM   12143 C CA  . ASN D 1 292 ? 78.899  121.725 119.930 1.00 19.65 ? 271  ASN D CA  1 
ATOM   12144 C C   . ASN D 1 292 ? 77.749  121.334 119.009 1.00 19.65 ? 271  ASN D C   1 
ATOM   12145 O O   . ASN D 1 292 ? 76.738  120.782 119.441 1.00 19.65 ? 271  ASN D O   1 
ATOM   12146 C CB  . ASN D 1 292 ? 78.539  121.516 121.396 1.00 19.65 ? 271  ASN D CB  1 
ATOM   12147 C CG  . ASN D 1 292 ? 79.043  120.203 121.928 1.00 19.65 ? 271  ASN D CG  1 
ATOM   12148 O OD1 . ASN D 1 292 ? 79.771  119.495 121.242 1.00 19.65 ? 271  ASN D OD1 1 
ATOM   12149 N ND2 . ASN D 1 292 ? 78.670  119.870 123.154 1.00 19.65 ? 271  ASN D ND2 1 
ATOM   12150 N N   . ILE D 1 293 ? 77.894  121.652 117.719 1.00 17.13 ? 272  ILE D N   1 
ATOM   12151 C CA  . ILE D 1 293 ? 76.781  121.638 116.773 1.00 17.13 ? 272  ILE D CA  1 
ATOM   12152 C C   . ILE D 1 293 ? 76.020  120.313 116.809 1.00 17.13 ? 272  ILE D C   1 
ATOM   12153 O O   . ILE D 1 293 ? 76.612  119.240 116.959 1.00 17.13 ? 272  ILE D O   1 
ATOM   12154 C CB  . ILE D 1 293 ? 77.297  121.919 115.350 1.00 17.13 ? 272  ILE D CB  1 
ATOM   12155 C CG1 . ILE D 1 293 ? 78.172  123.169 115.311 1.00 17.13 ? 272  ILE D CG1 1 
ATOM   12156 C CG2 . ILE D 1 293 ? 76.142  122.117 114.416 1.00 17.13 ? 272  ILE D CG2 1 
ATOM   12157 C CD1 . ILE D 1 293 ? 79.657  122.880 115.357 1.00 17.13 ? 272  ILE D CD1 1 
ATOM   12158 N N   . PHE D 1 294 ? 74.692  120.392 116.668 1.00 19.51 ? 273  PHE D N   1 
ATOM   12159 C CA  . PHE D 1 294 ? 73.826  119.227 116.484 1.00 19.51 ? 273  PHE D CA  1 
ATOM   12160 C C   . PHE D 1 294 ? 73.016  119.418 115.205 1.00 19.51 ? 273  PHE D C   1 
ATOM   12161 O O   . PHE D 1 294 ? 72.162  120.307 115.139 1.00 19.51 ? 273  PHE D O   1 
ATOM   12162 C CB  . PHE D 1 294 ? 72.899  119.029 117.680 1.00 19.51 ? 273  PHE D CB  1 
ATOM   12163 C CG  . PHE D 1 294 ? 73.609  118.677 118.948 1.00 19.51 ? 273  PHE D CG  1 
ATOM   12164 C CD1 . PHE D 1 294 ? 73.954  117.371 119.222 1.00 19.51 ? 273  PHE D CD1 1 
ATOM   12165 C CD2 . PHE D 1 294 ? 73.928  119.655 119.871 1.00 19.51 ? 273  PHE D CD2 1 
ATOM   12166 C CE1 . PHE D 1 294 ? 74.606  117.044 120.392 1.00 19.51 ? 273  PHE D CE1 1 
ATOM   12167 C CE2 . PHE D 1 294 ? 74.583  119.335 121.043 1.00 19.51 ? 273  PHE D CE2 1 
ATOM   12168 C CZ  . PHE D 1 294 ? 74.923  118.027 121.302 1.00 19.51 ? 273  PHE D CZ  1 
ATOM   12169 N N   . PHE D 1 295 ? 73.276  118.589 114.198 1.00 21.92 ? 274  PHE D N   1 
ATOM   12170 C CA  . PHE D 1 295 ? 72.624  118.716 112.889 1.00 21.92 ? 274  PHE D CA  1 
ATOM   12171 C C   . PHE D 1 295 ? 71.414  117.803 112.728 1.00 21.92 ? 274  PHE D C   1 
ATOM   12172 O O   . PHE D 1 295 ? 71.364  117.026 111.783 1.00 21.92 ? 274  PHE D O   1 
ATOM   12173 C CB  . PHE D 1 295 ? 73.621  118.445 111.772 1.00 21.92 ? 274  PHE D CB  1 
ATOM   12174 C CG  . PHE D 1 295 ? 74.414  119.636 111.357 1.00 21.92 ? 274  PHE D CG  1 
ATOM   12175 C CD1 . PHE D 1 295 ? 73.861  120.585 110.522 1.00 21.92 ? 274  PHE D CD1 1 
ATOM   12176 C CD2 . PHE D 1 295 ? 75.725  119.786 111.756 1.00 21.92 ? 274  PHE D CD2 1 
ATOM   12177 C CE1 . PHE D 1 295 ? 74.590  121.678 110.120 1.00 21.92 ? 274  PHE D CE1 1 
ATOM   12178 C CE2 . PHE D 1 295 ? 76.460  120.875 111.349 1.00 21.92 ? 274  PHE D CE2 1 
ATOM   12179 C CZ  . PHE D 1 295 ? 75.893  121.824 110.534 1.00 21.92 ? 274  PHE D CZ  1 
ATOM   12180 N N   . ALA D 1 296 ? 70.441  117.861 113.636 1.00 26.11 ? 275  ALA D N   1 
ATOM   12181 C CA  . ALA D 1 296 ? 69.078  117.397 113.373 1.00 26.11 ? 275  ALA D CA  1 
ATOM   12182 C C   . ALA D 1 296 ? 68.917  115.893 113.163 1.00 26.11 ? 275  ALA D C   1 
ATOM   12183 O O   . ALA D 1 296 ? 67.785  115.411 113.053 1.00 26.11 ? 275  ALA D O   1 
ATOM   12184 C CB  . ALA D 1 296 ? 68.506  118.129 112.157 1.00 26.11 ? 275  ALA D CB  1 
ATOM   12185 N N   . ASP D 1 297 ? 70.015  115.142 113.112 1.00 25.84 ? 276  ASP D N   1 
ATOM   12186 C CA  . ASP D 1 297 ? 69.945  113.678 113.044 1.00 25.84 ? 276  ASP D CA  1 
ATOM   12187 C C   . ASP D 1 297 ? 71.309  113.065 113.303 1.00 25.84 ? 276  ASP D C   1 
ATOM   12188 O O   . ASP D 1 297 ? 72.133  113.648 114.000 1.00 25.84 ? 276  ASP D O   1 
ATOM   12189 C CB  . ASP D 1 297 ? 69.406  113.182 111.691 1.00 25.84 ? 276  ASP D CB  1 
ATOM   12190 C CG  . ASP D 1 297 ? 70.163  113.744 110.504 1.00 25.84 ? 276  ASP D CG  1 
ATOM   12191 O OD1 . ASP D 1 297 ? 70.641  114.887 110.573 1.00 25.84 ? 276  ASP D OD1 1 
ATOM   12192 O OD2 . ASP D 1 297 ? 70.290  113.026 109.493 1.00 25.84 ? 276  ASP D OD2 1 
ATOM   12193 N N   . ARG D 1 329 ? 79.441  127.205 123.835 1.00 19.13 ? 308  ARG D N   1 
ATOM   12194 C CA  . ARG D 1 329 ? 78.564  127.286 122.675 1.00 19.13 ? 308  ARG D CA  1 
ATOM   12195 C C   . ARG D 1 329 ? 77.945  125.932 122.345 1.00 19.13 ? 308  ARG D C   1 
ATOM   12196 O O   . ARG D 1 329 ? 78.653  124.947 122.147 1.00 19.13 ? 308  ARG D O   1 
ATOM   12197 C CB  . ARG D 1 329 ? 79.331  127.823 121.466 1.00 19.13 ? 308  ARG D CB  1 
ATOM   12198 C CG  . ARG D 1 329 ? 79.802  129.256 121.622 1.00 19.13 ? 308  ARG D CG  1 
ATOM   12199 C CD  . ARG D 1 329 ? 81.099  129.505 120.880 1.00 19.13 ? 308  ARG D CD  1 
ATOM   12200 N NE  . ARG D 1 329 ? 81.915  130.525 121.534 1.00 19.13 ? 308  ARG D NE  1 
ATOM   12201 C CZ  . ARG D 1 329 ? 82.854  130.268 122.438 1.00 19.13 ? 308  ARG D CZ  1 
ATOM   12202 N NH1 . ARG D 1 329 ? 83.103  129.019 122.803 1.00 19.13 ? 308  ARG D NH1 1 
ATOM   12203 N NH2 . ARG D 1 329 ? 83.547  131.261 122.979 1.00 19.13 ? 308  ARG D NH2 1 
ATOM   12204 N N   . VAL D 1 330 ? 76.616  125.893 122.291 1.00 21.12 ? 309  VAL D N   1 
ATOM   12205 C CA  . VAL D 1 330 ? 75.863  124.695 121.931 1.00 21.12 ? 309  VAL D CA  1 
ATOM   12206 C C   . VAL D 1 330 ? 74.945  125.104 120.788 1.00 21.12 ? 309  VAL D C   1 
ATOM   12207 O O   . VAL D 1 330 ? 73.966  125.830 120.996 1.00 21.12 ? 309  VAL D O   1 
ATOM   12208 C CB  . VAL D 1 330 ? 75.073  124.119 123.112 1.00 21.12 ? 309  VAL D CB  1 
ATOM   12209 C CG1 . VAL D 1 330 ? 73.937  123.229 122.630 1.00 21.12 ? 309  VAL D CG1 1 
ATOM   12210 C CG2 . VAL D 1 330 ? 76.000  123.343 124.028 1.00 21.12 ? 309  VAL D CG2 1 
ATOM   12211 N N   . LEU D 1 331 ? 75.270  124.663 119.573 1.00 21.90 ? 310  LEU D N   1 
ATOM   12212 C CA  . LEU D 1 331 ? 74.572  125.103 118.369 1.00 21.90 ? 310  LEU D CA  1 
ATOM   12213 C C   . LEU D 1 331 ? 73.563  124.032 117.966 1.00 21.90 ? 310  LEU D C   1 
ATOM   12214 O O   . LEU D 1 331 ? 73.780  123.245 117.048 1.00 21.90 ? 310  LEU D O   1 
ATOM   12215 C CB  . LEU D 1 331 ? 75.567  125.389 117.250 1.00 21.90 ? 310  LEU D CB  1 
ATOM   12216 C CG  . LEU D 1 331 ? 76.097  126.816 117.101 1.00 21.90 ? 310  LEU D CG  1 
ATOM   12217 C CD1 . LEU D 1 331 ? 74.986  127.770 116.692 1.00 21.90 ? 310  LEU D CD1 1 
ATOM   12218 C CD2 . LEU D 1 331 ? 76.785  127.288 118.371 1.00 21.90 ? 310  LEU D CD2 1 
ATOM   12219 N N   . ILE D 1 332 ? 72.439  124.008 118.673 1.00 24.76 ? 311  ILE D N   1 
ATOM   12220 C CA  . ILE D 1 332 ? 71.359  123.079 118.357 1.00 24.76 ? 311  ILE D CA  1 
ATOM   12221 C C   . ILE D 1 332 ? 70.607  123.608 117.141 1.00 24.76 ? 311  ILE D C   1 
ATOM   12222 O O   . ILE D 1 332 ? 70.150  124.754 117.136 1.00 24.76 ? 311  ILE D O   1 
ATOM   12223 C CB  . ILE D 1 332 ? 70.417  122.899 119.555 1.00 24.76 ? 311  ILE D CB  1 
ATOM   12224 C CG1 . ILE D 1 332 ? 71.090  122.055 120.637 1.00 24.76 ? 311  ILE D CG1 1 
ATOM   12225 C CG2 . ILE D 1 332 ? 69.102  122.274 119.117 1.00 24.76 ? 311  ILE D CG2 1 
ATOM   12226 C CD1 . ILE D 1 332 ? 70.265  121.896 121.890 1.00 24.76 ? 311  ILE D CD1 1 
ATOM   12227 N N   . GLN D 1 333 ? 70.479  122.778 116.110 1.00 30.04 ? 312  GLN D N   1 
ATOM   12228 C CA  . GLN D 1 333 ? 69.779  123.193 114.897 1.00 30.04 ? 312  GLN D CA  1 
ATOM   12229 C C   . GLN D 1 333 ? 68.312  123.482 115.176 1.00 30.04 ? 312  GLN D C   1 
ATOM   12230 O O   . GLN D 1 333 ? 67.621  122.682 115.805 1.00 30.04 ? 312  GLN D O   1 
ATOM   12231 C CB  . GLN D 1 333 ? 69.895  122.131 113.803 1.00 30.04 ? 312  GLN D CB  1 
ATOM   12232 C CG  . GLN D 1 333 ? 68.999  122.401 112.604 1.00 30.04 ? 312  GLN D CG  1 
ATOM   12233 C CD  . GLN D 1 333 ? 69.602  121.930 111.293 1.00 30.04 ? 312  GLN D CD  1 
ATOM   12234 O OE1 . GLN D 1 333 ? 70.033  120.785 111.169 1.00 30.04 ? 312  GLN D OE1 1 
ATOM   12235 N NE2 . GLN D 1 333 ? 69.633  122.815 110.305 1.00 30.04 ? 312  GLN D NE2 1 
ATOM   12236 N N   . VAL D 1 433 ? 73.947  127.597 125.032 1.00 21.37 ? 412  VAL D N   1 
ATOM   12237 C CA  . VAL D 1 433 ? 72.934  127.071 124.129 1.00 21.37 ? 412  VAL D CA  1 
ATOM   12238 C C   . VAL D 1 433 ? 72.419  128.186 123.225 1.00 21.37 ? 412  VAL D C   1 
ATOM   12239 O O   . VAL D 1 433 ? 72.298  129.333 123.644 1.00 21.37 ? 412  VAL D O   1 
ATOM   12240 C CB  . VAL D 1 433 ? 71.786  126.406 124.908 1.00 21.37 ? 412  VAL D CB  1 
ATOM   12241 C CG1 . VAL D 1 433 ? 70.809  125.733 123.960 1.00 21.37 ? 412  VAL D CG1 1 
ATOM   12242 C CG2 . VAL D 1 433 ? 72.339  125.399 125.900 1.00 21.37 ? 412  VAL D CG2 1 
ATOM   12243 N N   . THR D 1 434 ? 72.134  127.835 121.980 1.00 22.12 ? 413  THR D N   1 
ATOM   12244 C CA  . THR D 1 434 ? 71.670  128.760 120.950 1.00 22.12 ? 413  THR D CA  1 
ATOM   12245 C C   . THR D 1 434 ? 71.107  127.915 119.813 1.00 22.12 ? 413  THR D C   1 
ATOM   12246 O O   . THR D 1 434 ? 70.943  126.698 119.952 1.00 22.12 ? 413  THR D O   1 
ATOM   12247 C CB  . THR D 1 434 ? 72.790  129.697 120.489 1.00 22.12 ? 413  THR D CB  1 
ATOM   12248 O OG1 . THR D 1 434 ? 72.298  130.569 119.464 1.00 22.12 ? 413  THR D OG1 1 
ATOM   12249 C CG2 . THR D 1 434 ? 73.968  128.910 119.963 1.00 22.12 ? 413  THR D CG2 1 
ATOM   12250 N N   . THR D 1 435 ? 70.800  128.554 118.688 1.00 25.43 ? 414  THR D N   1 
ATOM   12251 C CA  . THR D 1 435 ? 70.158  127.848 117.591 1.00 25.43 ? 414  THR D CA  1 
ATOM   12252 C C   . THR D 1 435 ? 70.647  128.402 116.263 1.00 25.43 ? 414  THR D C   1 
ATOM   12253 O O   . THR D 1 435 ? 71.222  129.492 116.191 1.00 25.43 ? 414  THR D O   1 
ATOM   12254 C CB  . THR D 1 435 ? 68.630  127.946 117.674 1.00 25.43 ? 414  THR D CB  1 
ATOM   12255 O OG1 . THR D 1 435 ? 68.041  127.067 116.707 1.00 25.43 ? 414  THR D OG1 1 
ATOM   12256 C CG2 . THR D 1 435 ? 68.170  129.371 117.404 1.00 25.43 ? 414  THR D CG2 1 
ATOM   12257 N N   . PHE D 1 436 ? 70.412  127.626 115.208 1.00 30.65 ? 415  PHE D N   1 
ATOM   12258 C CA  . PHE D 1 436 ? 70.803  128.003 113.859 1.00 30.65 ? 415  PHE D CA  1 
ATOM   12259 C C   . PHE D 1 436 ? 69.843  127.344 112.877 1.00 30.65 ? 415  PHE D C   1 
ATOM   12260 O O   . PHE D 1 436 ? 68.933  126.607 113.266 1.00 30.65 ? 415  PHE D O   1 
ATOM   12261 C CB  . PHE D 1 436 ? 72.266  127.636 113.583 1.00 30.65 ? 415  PHE D CB  1 
ATOM   12262 C CG  . PHE D 1 436 ? 72.506  126.168 113.352 1.00 30.65 ? 415  PHE D CG  1 
ATOM   12263 C CD1 . PHE D 1 436 ? 72.432  125.626 112.081 1.00 30.65 ? 415  PHE D CD1 1 
ATOM   12264 C CD2 . PHE D 1 436 ? 72.845  125.336 114.403 1.00 30.65 ? 415  PHE D CD2 1 
ATOM   12265 C CE1 . PHE D 1 436 ? 72.669  124.283 111.869 1.00 30.65 ? 415  PHE D CE1 1 
ATOM   12266 C CE2 . PHE D 1 436 ? 73.083  123.995 114.192 1.00 30.65 ? 415  PHE D CE2 1 
ATOM   12267 C CZ  . PHE D 1 436 ? 72.994  123.469 112.925 1.00 30.65 ? 415  PHE D CZ  1 
ATOM   12268 N N   . LYS D 1 437 ? 70.055  127.613 111.589 1.00 33.70 ? 416  LYS D N   1 
ATOM   12269 C CA  . LYS D 1 437 ? 69.103  127.231 110.555 1.00 33.70 ? 416  LYS D CA  1 
ATOM   12270 C C   . LYS D 1 437 ? 69.621  126.118 109.654 1.00 33.70 ? 416  LYS D C   1 
ATOM   12271 O O   . LYS D 1 437 ? 68.977  125.071 109.536 1.00 33.70 ? 416  LYS D O   1 
ATOM   12272 C CB  . LYS D 1 437 ? 68.739  128.464 109.717 1.00 33.70 ? 416  LYS D CB  1 
ATOM   12273 C CG  . LYS D 1 437 ? 68.029  129.559 110.492 1.00 33.70 ? 416  LYS D CG  1 
ATOM   12274 C CD  . LYS D 1 437 ? 67.590  130.679 109.566 1.00 33.70 ? 416  LYS D CD  1 
ATOM   12275 C CE  . LYS D 1 437 ? 68.747  131.178 108.719 1.00 33.70 ? 416  LYS D CE  1 
ATOM   12276 N NZ  . LYS D 1 437 ? 68.345  132.303 107.836 1.00 33.70 ? 416  LYS D NZ  1 
ATOM   12277 N N   . ASP D 1 438 ? 70.776  126.308 109.016 1.00 33.51 ? 417  ASP D N   1 
ATOM   12278 C CA  . ASP D 1 438 ? 71.277  125.365 108.027 1.00 33.51 ? 417  ASP D CA  1 
ATOM   12279 C C   . ASP D 1 438 ? 72.767  125.145 108.251 1.00 33.51 ? 417  ASP D C   1 
ATOM   12280 O O   . ASP D 1 438 ? 73.361  125.679 109.191 1.00 33.51 ? 417  ASP D O   1 
ATOM   12281 C CB  . ASP D 1 438 ? 70.993  125.859 106.607 1.00 33.51 ? 417  ASP D CB  1 
ATOM   12282 C CG  . ASP D 1 438 ? 69.512  126.015 106.333 1.00 33.51 ? 417  ASP D CG  1 
ATOM   12283 O OD1 . ASP D 1 438 ? 68.920  127.006 106.811 1.00 33.51 ? 417  ASP D OD1 1 
ATOM   12284 O OD2 . ASP D 1 438 ? 68.939  125.146 105.644 1.00 33.51 ? 417  ASP D OD2 1 
ATOM   12285 N N   . GLN D 1 439 ? 73.374  124.346 107.370 1.00 27.07 ? 418  GLN D N   1 
ATOM   12286 C CA  . GLN D 1 439 ? 74.785  124.002 107.525 1.00 27.07 ? 418  GLN D CA  1 
ATOM   12287 C C   . GLN D 1 439 ? 75.664  125.243 107.472 1.00 27.07 ? 418  GLN D C   1 
ATOM   12288 O O   . GLN D 1 439 ? 76.477  125.483 108.373 1.00 27.07 ? 418  GLN D O   1 
ATOM   12289 C CB  . GLN D 1 439 ? 75.201  123.006 106.444 1.00 27.07 ? 418  GLN D CB  1 
ATOM   12290 C CG  . GLN D 1 439 ? 76.701  122.897 106.245 1.00 27.07 ? 418  GLN D CG  1 
ATOM   12291 C CD  . GLN D 1 439 ? 77.091  121.676 105.442 1.00 27.07 ? 418  GLN D CD  1 
ATOM   12292 O OE1 . GLN D 1 439 ? 76.435  120.638 105.513 1.00 27.07 ? 418  GLN D OE1 1 
ATOM   12293 N NE2 . GLN D 1 439 ? 78.166  121.794 104.670 1.00 27.07 ? 418  GLN D NE2 1 
ATOM   12294 N N   . ALA D 1 440 ? 75.503  126.053 106.424 1.00 25.39 ? 419  ALA D N   1 
ATOM   12295 C CA  . ALA D 1 440 ? 76.307  127.261 106.302 1.00 25.39 ? 419  ALA D CA  1 
ATOM   12296 C C   . ALA D 1 440 ? 76.039  128.225 107.447 1.00 25.39 ? 419  ALA D C   1 
ATOM   12297 O O   . ALA D 1 440 ? 76.930  128.985 107.834 1.00 25.39 ? 419  ALA D O   1 
ATOM   12298 C CB  . ALA D 1 440 ? 76.043  127.941 104.960 1.00 25.39 ? 419  ALA D CB  1 
ATOM   12299 N N   . GLU D 1 441 ? 74.828  128.199 108.009 1.00 28.98 ? 420  GLU D N   1 
ATOM   12300 C CA  . GLU D 1 441 ? 74.512  129.072 109.135 1.00 28.98 ? 420  GLU D CA  1 
ATOM   12301 C C   . GLU D 1 441 ? 75.415  128.776 110.326 1.00 28.98 ? 420  GLU D C   1 
ATOM   12302 O O   . GLU D 1 441 ? 76.118  129.662 110.828 1.00 28.98 ? 420  GLU D O   1 
ATOM   12303 C CB  . GLU D 1 441 ? 73.039  128.913 109.514 1.00 28.98 ? 420  GLU D CB  1 
ATOM   12304 C CG  . GLU D 1 441 ? 72.564  129.865 110.597 1.00 28.98 ? 420  GLU D CG  1 
ATOM   12305 C CD  . GLU D 1 441 ? 72.111  131.200 110.050 1.00 28.98 ? 420  GLU D CD  1 
ATOM   12306 O OE1 . GLU D 1 441 ? 71.507  131.980 110.818 1.00 28.98 ? 420  GLU D OE1 1 
ATOM   12307 O OE2 . GLU D 1 441 ? 72.355  131.472 108.856 1.00 28.98 ? 420  GLU D OE2 1 
ATOM   12308 N N   . ALA D 1 442 ? 75.441  127.516 110.768 1.00 24.92 ? 421  ALA D N   1 
ATOM   12309 C CA  . ALA D 1 442 ? 76.315  127.121 111.864 1.00 24.92 ? 421  ALA D CA  1 
ATOM   12310 C C   . ALA D 1 442 ? 77.779  127.089 111.460 1.00 24.92 ? 421  ALA D C   1 
ATOM   12311 O O   . ALA D 1 442 ? 78.642  126.996 112.339 1.00 24.92 ? 421  ALA D O   1 
ATOM   12312 C CB  . ALA D 1 442 ? 75.907  125.753 112.408 1.00 24.92 ? 421  ALA D CB  1 
ATOM   12313 N N   . LEU D 1 443 ? 78.082  127.147 110.164 1.00 19.99 ? 422  LEU D N   1 
ATOM   12314 C CA  . LEU D 1 443 ? 79.469  127.318 109.749 1.00 19.99 ? 422  LEU D CA  1 
ATOM   12315 C C   . LEU D 1 443 ? 79.936  128.750 109.981 1.00 19.99 ? 422  LEU D C   1 
ATOM   12316 O O   . LEU D 1 443 ? 81.011  128.975 110.547 1.00 19.99 ? 422  LEU D O   1 
ATOM   12317 C CB  . LEU D 1 443 ? 79.634  126.927 108.281 1.00 19.99 ? 422  LEU D CB  1 
ATOM   12318 C CG  . LEU D 1 443 ? 81.064  126.698 107.794 1.00 19.99 ? 422  LEU D CG  1 
ATOM   12319 C CD1 . LEU D 1 443 ? 81.660  125.471 108.450 1.00 19.99 ? 422  LEU D CD1 1 
ATOM   12320 C CD2 . LEU D 1 443 ? 81.092  126.563 106.285 1.00 19.99 ? 422  LEU D CD2 1 
ATOM   12321 N N   . GLU D 1 444 ? 79.140  129.734 109.554 1.00 23.73 ? 423  GLU D N   1 
ATOM   12322 C CA  . GLU D 1 444 ? 79.538  131.124 109.752 1.00 23.73 ? 423  GLU D CA  1 
ATOM   12323 C C   . GLU D 1 444 ? 79.377  131.567 111.197 1.00 23.73 ? 423  GLU D C   1 
ATOM   12324 O O   . GLU D 1 444 ? 80.013  132.546 111.602 1.00 23.73 ? 423  GLU D O   1 
ATOM   12325 C CB  . GLU D 1 444 ? 78.756  132.068 108.832 1.00 23.73 ? 423  GLU D CB  1 
ATOM   12326 C CG  . GLU D 1 444 ? 77.277  131.790 108.717 1.00 23.73 ? 423  GLU D CG  1 
ATOM   12327 C CD  . GLU D 1 444 ? 76.559  132.808 107.857 1.00 23.73 ? 423  GLU D CD  1 
ATOM   12328 O OE1 . GLU D 1 444 ? 75.614  132.418 107.142 1.00 23.73 ? 423  GLU D OE1 1 
ATOM   12329 O OE2 . GLU D 1 444 ? 76.937  133.997 107.893 1.00 23.73 ? 423  GLU D OE2 1 
ATOM   12330 N N   . ILE D 1 445 ? 78.547  130.881 111.984 1.00 23.18 ? 424  ILE D N   1 
ATOM   12331 C CA  . ILE D 1 445 ? 78.501  131.159 113.417 1.00 23.18 ? 424  ILE D CA  1 
ATOM   12332 C C   . ILE D 1 445 ? 79.819  130.771 114.078 1.00 23.18 ? 424  ILE D C   1 
ATOM   12333 O O   . ILE D 1 445 ? 80.388  131.534 114.866 1.00 23.18 ? 424  ILE D O   1 
ATOM   12334 C CB  . ILE D 1 445 ? 77.307  130.447 114.073 1.00 23.18 ? 424  ILE D CB  1 
ATOM   12335 C CG1 . ILE D 1 445 ? 75.997  130.989 113.500 1.00 23.18 ? 424  ILE D CG1 1 
ATOM   12336 C CG2 . ILE D 1 445 ? 77.354  130.607 115.583 1.00 23.18 ? 424  ILE D CG2 1 
ATOM   12337 C CD1 . ILE D 1 445 ? 74.775  130.187 113.880 1.00 23.18 ? 424  ILE D CD1 1 
ATOM   12338 N N   . ALA D 1 446 ? 80.332  129.591 113.757 1.00 19.95 ? 425  ALA D N   1 
ATOM   12339 C CA  . ALA D 1 446 ? 81.589  129.138 114.336 1.00 19.95 ? 425  ALA D CA  1 
ATOM   12340 C C   . ALA D 1 446 ? 82.788  129.775 113.636 1.00 19.95 ? 425  ALA D C   1 
ATOM   12341 O O   . ALA D 1 446 ? 83.005  129.580 112.439 1.00 19.95 ? 425  ALA D O   1 
ATOM   12342 C CB  . ALA D 1 446 ? 81.681  127.627 114.274 1.00 19.95 ? 425  ALA D CB  1 
ATOM   12343 N N   . GLY D 1 454 ? 88.021  123.082 120.291 1.00 14.02 ? 433  GLY D N   1 
ATOM   12344 C CA  . GLY D 1 454 ? 87.897  123.175 118.849 1.00 14.02 ? 433  GLY D CA  1 
ATOM   12345 C C   . GLY D 1 454 ? 86.468  123.296 118.359 1.00 14.02 ? 433  GLY D C   1 
ATOM   12346 O O   . GLY D 1 454 ? 85.960  124.401 118.190 1.00 14.02 ? 433  GLY D O   1 
ATOM   12347 N N   . ALA D 1 455 ? 85.824  122.162 118.113 1.00 14.12 ? 434  ALA D N   1 
ATOM   12348 C CA  . ALA D 1 455 ? 84.414  122.140 117.735 1.00 14.12 ? 434  ALA D CA  1 
ATOM   12349 C C   . ALA D 1 455 ? 83.812  120.820 118.209 1.00 14.12 ? 434  ALA D C   1 
ATOM   12350 O O   . ALA D 1 455 ? 84.408  120.110 119.024 1.00 14.12 ? 434  ALA D O   1 
ATOM   12351 C CB  . ALA D 1 455 ? 84.260  122.360 116.220 1.00 14.12 ? 434  ALA D CB  1 
ATOM   12352 N N   . GLY D 1 456 ? 82.617  120.504 117.716 1.00 14.89 ? 435  GLY D N   1 
ATOM   12353 C CA  . GLY D 1 456 ? 82.004  119.204 117.912 1.00 14.89 ? 435  GLY D CA  1 
ATOM   12354 C C   . GLY D 1 456 ? 80.777  119.058 117.035 1.00 14.89 ? 435  GLY D C   1 
ATOM   12355 O O   . GLY D 1 456 ? 79.911  119.935 117.043 1.00 14.89 ? 435  GLY D O   1 
ATOM   12356 N N   . VAL D 1 457 ? 80.680  117.965 116.277 1.00 13.57 ? 436  VAL D N   1 
ATOM   12357 C CA  . VAL D 1 457 ? 79.668  117.854 115.229 1.00 13.57 ? 436  VAL D CA  1 
ATOM   12358 C C   . VAL D 1 457 ? 78.966  116.502 115.261 1.00 13.57 ? 436  VAL D C   1 
ATOM   12359 O O   . VAL D 1 457 ? 79.532  115.488 114.847 1.00 13.57 ? 436  VAL D O   1 
ATOM   12360 C CB  . VAL D 1 457 ? 80.288  118.099 113.840 1.00 13.57 ? 436  VAL D CB  1 
ATOM   12361 C CG1 . VAL D 1 457 ? 79.229  118.016 112.767 1.00 13.57 ? 436  VAL D CG1 1 
ATOM   12362 C CG2 . VAL D 1 457 ? 80.966  119.449 113.782 1.00 13.57 ? 436  VAL D CG2 1 
ATOM   12363 N N   . TRP D 1 458 ? 77.725  116.482 115.737 1.00 15.94 ? 437  TRP D N   1 
ATOM   12364 C CA  . TRP D 1 458 ? 76.837  115.335 115.586 1.00 15.94 ? 437  TRP D CA  1 
ATOM   12365 C C   . TRP D 1 458 ? 75.972  115.484 114.345 1.00 15.94 ? 437  TRP D C   1 
ATOM   12366 O O   . TRP D 1 458 ? 75.237  116.466 114.205 1.00 15.94 ? 437  TRP D O   1 
ATOM   12367 C CB  . TRP D 1 458 ? 75.969  115.141 116.831 1.00 15.94 ? 437  TRP D CB  1 
ATOM   12368 C CG  . TRP D 1 458 ? 76.729  114.681 118.033 1.00 15.94 ? 437  TRP D CG  1 
ATOM   12369 C CD1 . TRP D 1 458 ? 76.953  113.389 118.395 1.00 15.94 ? 437  TRP D CD1 1 
ATOM   12370 C CD2 . TRP D 1 458 ? 77.483  115.481 118.940 1.00 15.94 ? 437  TRP D CD2 1 
ATOM   12371 N NE1 . TRP D 1 458 ? 77.729  113.334 119.518 1.00 15.94 ? 437  TRP D NE1 1 
ATOM   12372 C CE2 . TRP D 1 458 ? 78.079  114.607 119.870 1.00 15.94 ? 437  TRP D CE2 1 
ATOM   12373 C CE3 . TRP D 1 458 ? 77.685  116.851 119.080 1.00 15.94 ? 437  TRP D CE3 1 
ATOM   12374 C CZ2 . TRP D 1 458 ? 78.863  115.057 120.918 1.00 15.94 ? 437  TRP D CZ2 1 
ATOM   12375 C CZ3 . TRP D 1 458 ? 78.457  117.292 120.119 1.00 15.94 ? 437  TRP D CZ3 1 
ATOM   12376 C CH2 . TRP D 1 458 ? 79.043  116.405 121.026 1.00 15.94 ? 437  TRP D CH2 1 
ATOM   12377 N N   . SER D 1 459 ? 76.075  114.505 113.454 1.00 16.47 ? 438  SER D N   1 
ATOM   12378 C CA  . SER D 1 459 ? 75.219  114.353 112.284 1.00 16.47 ? 438  SER D CA  1 
ATOM   12379 C C   . SER D 1 459 ? 75.492  112.968 111.711 1.00 16.47 ? 438  SER D C   1 
ATOM   12380 O O   . SER D 1 459 ? 76.284  112.196 112.258 1.00 16.47 ? 438  SER D O   1 
ATOM   12381 C CB  . SER D 1 459 ? 75.470  115.444 111.250 1.00 16.47 ? 438  SER D CB  1 
ATOM   12382 O OG  . SER D 1 459 ? 74.522  115.361 110.203 1.00 16.47 ? 438  SER D OG  1 
ATOM   12383 N N   . ARG D 1 460 ? 74.825  112.654 110.599 1.00 19.97 ? 439  ARG D N   1 
ATOM   12384 C CA  . ARG D 1 460 ? 75.001  111.356 109.963 1.00 19.97 ? 439  ARG D CA  1 
ATOM   12385 C C   . ARG D 1 460 ? 75.117  111.416 108.448 1.00 19.97 ? 439  ARG D C   1 
ATOM   12386 O O   . ARG D 1 460 ? 75.198  110.358 107.820 1.00 19.97 ? 439  ARG D O   1 
ATOM   12387 C CB  . ARG D 1 460 ? 73.841  110.414 110.333 1.00 19.97 ? 439  ARG D CB  1 
ATOM   12388 C CG  . ARG D 1 460 ? 73.288  110.613 111.732 1.00 19.97 ? 439  ARG D CG  1 
ATOM   12389 C CD  . ARG D 1 460 ? 72.434  109.449 112.181 1.00 19.97 ? 439  ARG D CD  1 
ATOM   12390 N NE  . ARG D 1 460 ? 71.324  109.197 111.269 1.00 19.97 ? 439  ARG D NE  1 
ATOM   12391 C CZ  . ARG D 1 460 ? 70.124  108.779 111.655 1.00 19.97 ? 439  ARG D CZ  1 
ATOM   12392 N NH1 . ARG D 1 460 ? 69.874  108.571 112.942 1.00 19.97 ? 439  ARG D NH1 1 
ATOM   12393 N NH2 . ARG D 1 460 ? 69.171  108.572 110.757 1.00 19.97 ? 439  ARG D NH2 1 
ATOM   12394 N N   . ASP D 1 461 ? 75.143  112.602 107.840 1.00 17.51 ? 440  ASP D N   1 
ATOM   12395 C CA  . ASP D 1 461 ? 75.081  112.707 106.387 1.00 17.51 ? 440  ASP D CA  1 
ATOM   12396 C C   . ASP D 1 461 ? 76.393  112.342 105.701 1.00 17.51 ? 440  ASP D C   1 
ATOM   12397 O O   . ASP D 1 461 ? 76.397  112.126 104.485 1.00 17.51 ? 440  ASP D O   1 
ATOM   12398 C CB  . ASP D 1 461 ? 74.666  114.125 105.989 1.00 17.51 ? 440  ASP D CB  1 
ATOM   12399 C CG  . ASP D 1 461 ? 74.452  114.283 104.491 1.00 17.51 ? 440  ASP D CG  1 
ATOM   12400 O OD1 . ASP D 1 461 ? 74.033  113.308 103.834 1.00 17.51 ? 440  ASP D OD1 1 
ATOM   12401 O OD2 . ASP D 1 461 ? 74.709  115.387 103.971 1.00 17.51 ? 440  ASP D OD2 1 
ATOM   12402 N N   . ALA D 1 462 ? 77.505  112.307 106.435 1.00 14.41 ? 441  ALA D N   1 
ATOM   12403 C CA  . ALA D 1 462 ? 78.802  111.881 105.914 1.00 14.41 ? 441  ALA D CA  1 
ATOM   12404 C C   . ALA D 1 462 ? 79.342  112.843 104.864 1.00 14.41 ? 441  ALA D C   1 
ATOM   12405 O O   . ALA D 1 462 ? 80.462  112.670 104.378 1.00 14.41 ? 441  ALA D O   1 
ATOM   12406 C CB  . ALA D 1 462 ? 78.729  110.466 105.335 1.00 14.41 ? 441  ALA D CB  1 
ATOM   12407 N N   . ASN D 1 463 ? 78.553  113.850 104.503 1.00 13.18 ? 442  ASN D N   1 
ATOM   12408 C CA  . ASN D 1 463 ? 79.021  114.971 103.706 1.00 13.18 ? 442  ASN D CA  1 
ATOM   12409 C C   . ASN D 1 463 ? 78.820  116.286 104.429 1.00 13.18 ? 442  ASN D C   1 
ATOM   12410 O O   . ASN D 1 463 ? 79.277  117.321 103.940 1.00 13.18 ? 442  ASN D O   1 
ATOM   12411 C CB  . ASN D 1 463 ? 78.310  115.021 102.348 1.00 13.18 ? 442  ASN D CB  1 
ATOM   12412 C CG  . ASN D 1 463 ? 78.920  114.083 101.342 1.00 13.18 ? 442  ASN D CG  1 
ATOM   12413 O OD1 . ASN D 1 463 ? 79.428  113.022 101.696 1.00 13.18 ? 442  ASN D OD1 1 
ATOM   12414 N ND2 . ASN D 1 463 ? 78.875  114.465 100.074 1.00 13.18 ? 442  ASN D ND2 1 
ATOM   12415 N N   . THR D 1 464 ? 78.129  116.279 105.562 1.00 14.11 ? 443  THR D N   1 
ATOM   12416 C CA  . THR D 1 464 ? 78.138  117.409 106.475 1.00 14.11 ? 443  THR D CA  1 
ATOM   12417 C C   . THR D 1 464 ? 79.128  117.221 107.610 1.00 14.11 ? 443  THR D C   1 
ATOM   12418 O O   . THR D 1 464 ? 79.699  118.205 108.081 1.00 14.11 ? 443  THR D O   1 
ATOM   12419 C CB  . THR D 1 464 ? 76.733  117.658 107.044 1.00 14.11 ? 443  THR D CB  1 
ATOM   12420 O OG1 . THR D 1 464 ? 76.717  118.887 107.780 1.00 14.11 ? 443  THR D OG1 1 
ATOM   12421 C CG2 . THR D 1 464 ? 76.310  116.539 107.955 1.00 14.11 ? 443  THR D CG2 1 
ATOM   12422 N N   . CYS D 1 465 ? 79.362  115.980 108.044 1.00 12.05 ? 444  CYS D N   1 
ATOM   12423 C CA  . CYS D 1 465 ? 80.387  115.735 109.050 1.00 12.05 ? 444  CYS D CA  1 
ATOM   12424 C C   . CYS D 1 465 ? 81.759  116.140 108.534 1.00 12.05 ? 444  CYS D C   1 
ATOM   12425 O O   . CYS D 1 465 ? 82.537  116.778 109.250 1.00 12.05 ? 444  CYS D O   1 
ATOM   12426 C CB  . CYS D 1 465 ? 80.383  114.264 109.460 1.00 12.05 ? 444  CYS D CB  1 
ATOM   12427 S SG  . CYS D 1 465 ? 78.965  113.755 110.450 1.00 12.05 ? 444  CYS D SG  1 
ATOM   12428 N N   . TYR D 1 466 ? 82.068  115.796 107.284 1.00 6.71  ? 445  TYR D N   1 
ATOM   12429 C CA  . TYR D 1 466 ? 83.352  116.183 106.714 1.00 6.71  ? 445  TYR D CA  1 
ATOM   12430 C C   . TYR D 1 466 ? 83.424  117.682 106.471 1.00 6.71  ? 445  TYR D C   1 
ATOM   12431 O O   . TYR D 1 466 ? 84.418  118.328 106.816 1.00 6.71  ? 445  TYR D O   1 
ATOM   12432 C CB  . TYR D 1 466 ? 83.601  115.433 105.414 1.00 6.71  ? 445  TYR D CB  1 
ATOM   12433 C CG  . TYR D 1 466 ? 84.909  115.792 104.772 1.00 6.71  ? 445  TYR D CG  1 
ATOM   12434 C CD1 . TYR D 1 466 ? 86.103  115.320 105.281 1.00 6.71  ? 445  TYR D CD1 1 
ATOM   12435 C CD2 . TYR D 1 466 ? 84.954  116.616 103.663 1.00 6.71  ? 445  TYR D CD2 1 
ATOM   12436 C CE1 . TYR D 1 466 ? 87.304  115.649 104.697 1.00 6.71  ? 445  TYR D CE1 1 
ATOM   12437 C CE2 . TYR D 1 466 ? 86.150  116.951 103.074 1.00 6.71  ? 445  TYR D CE2 1 
ATOM   12438 C CZ  . TYR D 1 466 ? 87.320  116.465 103.597 1.00 6.71  ? 445  TYR D CZ  1 
ATOM   12439 O OH  . TYR D 1 466 ? 88.513  116.798 103.014 1.00 6.71  ? 445  TYR D OH  1 
ATOM   12440 N N   . ARG D 1 467 ? 82.393  118.249 105.845 1.00 8.21  ? 446  ARG D N   1 
ATOM   12441 C CA  . ARG D 1 467 ? 82.424  119.672 105.536 1.00 8.21  ? 446  ARG D CA  1 
ATOM   12442 C C   . ARG D 1 467 ? 82.466  120.503 106.806 1.00 8.21  ? 446  ARG D C   1 
ATOM   12443 O O   . ARG D 1 467 ? 83.202  121.490 106.885 1.00 8.21  ? 446  ARG D O   1 
ATOM   12444 C CB  . ARG D 1 467 ? 81.218  120.058 104.685 1.00 8.21  ? 446  ARG D CB  1 
ATOM   12445 C CG  . ARG D 1 467 ? 81.278  119.539 103.264 1.00 8.21  ? 446  ARG D CG  1 
ATOM   12446 C CD  . ARG D 1 467 ? 82.677  119.578 102.709 1.00 8.21  ? 446  ARG D CD  1 
ATOM   12447 N NE  . ARG D 1 467 ? 82.718  119.092 101.339 1.00 8.21  ? 446  ARG D NE  1 
ATOM   12448 C CZ  . ARG D 1 467 ? 83.698  119.364 100.490 1.00 8.21  ? 446  ARG D CZ  1 
ATOM   12449 N NH1 . ARG D 1 467 ? 84.714  120.119 100.880 1.00 8.21  ? 446  ARG D NH1 1 
ATOM   12450 N NH2 . ARG D 1 467 ? 83.667  118.881 99.257  1.00 8.21  ? 446  ARG D NH2 1 
ATOM   12451 N N   . MET D 1 468 ? 81.688  120.115 107.813 1.00 11.58 ? 447  MET D N   1 
ATOM   12452 C CA  . MET D 1 468 ? 81.698  120.837 109.076 1.00 11.58 ? 447  MET D CA  1 
ATOM   12453 C C   . MET D 1 468 ? 82.934  120.542 109.910 1.00 11.58 ? 447  MET D C   1 
ATOM   12454 O O   . MET D 1 468 ? 83.257  121.324 110.803 1.00 11.58 ? 447  MET D O   1 
ATOM   12455 C CB  . MET D 1 468 ? 80.443  120.509 109.875 1.00 11.58 ? 447  MET D CB  1 
ATOM   12456 C CG  . MET D 1 468 ? 79.207  121.171 109.327 1.00 11.58 ? 447  MET D CG  1 
ATOM   12457 S SD  . MET D 1 468 ? 79.357  122.954 109.414 1.00 11.58 ? 447  MET D SD  1 
ATOM   12458 C CE  . MET D 1 468 ? 79.428  123.179 111.188 1.00 11.58 ? 447  MET D CE  1 
ATOM   12459 N N   . GLY D 1 469 ? 83.625  119.430 109.657 1.00 7.47  ? 448  GLY D N   1 
ATOM   12460 C CA  . GLY D 1 469 ? 84.880  119.190 110.342 1.00 7.47  ? 448  GLY D CA  1 
ATOM   12461 C C   . GLY D 1 469 ? 86.043  119.925 109.720 1.00 7.47  ? 448  GLY D C   1 
ATOM   12462 O O   . GLY D 1 469 ? 86.985  120.303 110.423 1.00 7.47  ? 448  GLY D O   1 
ATOM   12463 N N   . ARG D 1 470 ? 86.000  120.141 108.409 1.00 4.60  ? 449  ARG D N   1 
ATOM   12464 C CA  . ARG D 1 470 ? 87.058  120.856 107.713 1.00 4.60  ? 449  ARG D CA  1 
ATOM   12465 C C   . ARG D 1 470 ? 86.846  122.362 107.695 1.00 4.60  ? 449  ARG D C   1 
ATOM   12466 O O   . ARG D 1 470 ? 87.826  123.110 107.630 1.00 4.60  ? 449  ARG D O   1 
ATOM   12467 C CB  . ARG D 1 470 ? 87.183  120.351 106.273 1.00 4.60  ? 449  ARG D CB  1 
ATOM   12468 C CG  . ARG D 1 470 ? 87.865  119.002 106.134 1.00 4.60  ? 449  ARG D CG  1 
ATOM   12469 C CD  . ARG D 1 470 ? 89.231  118.964 106.800 1.00 4.60  ? 449  ARG D CD  1 
ATOM   12470 N NE  . ARG D 1 470 ? 90.218  119.795 106.118 1.00 4.60  ? 449  ARG D NE  1 
ATOM   12471 C CZ  . ARG D 1 470 ? 90.869  119.437 105.016 1.00 4.60  ? 449  ARG D CZ  1 
ATOM   12472 N NH1 . ARG D 1 470 ? 90.638  118.260 104.459 1.00 4.60  ? 449  ARG D NH1 1 
ATOM   12473 N NH2 . ARG D 1 470 ? 91.754  120.255 104.471 1.00 4.60  ? 449  ARG D NH2 1 
ATOM   12474 N N   . GLY D 1 471 ? 85.600  122.824 107.755 1.00 8.63  ? 450  GLY D N   1 
ATOM   12475 C CA  . GLY D 1 471 ? 85.297  124.235 107.654 1.00 8.63  ? 450  GLY D CA  1 
ATOM   12476 C C   . GLY D 1 471 ? 85.404  125.028 108.929 1.00 8.63  ? 450  GLY D C   1 
ATOM   12477 O O   . GLY D 1 471 ? 85.243  126.249 108.898 1.00 8.63  ? 450  GLY D O   1 
ATOM   12478 N N   . ILE D 1 472 ? 85.671  124.375 110.052 1.00 11.16 ? 451  ILE D N   1 
ATOM   12479 C CA  . ILE D 1 472 ? 85.797  125.055 111.334 1.00 11.16 ? 451  ILE D CA  1 
ATOM   12480 C C   . ILE D 1 472 ? 87.237  125.508 111.509 1.00 11.16 ? 451  ILE D C   1 
ATOM   12481 O O   . ILE D 1 472 ? 88.174  124.729 111.301 1.00 11.16 ? 451  ILE D O   1 
ATOM   12482 C CB  . ILE D 1 472 ? 85.358  124.146 112.492 1.00 11.16 ? 451  ILE D CB  1 
ATOM   12483 C CG1 . ILE D 1 472 ? 83.885  123.785 112.352 1.00 11.16 ? 451  ILE D CG1 1 
ATOM   12484 C CG2 . ILE D 1 472 ? 85.576  124.832 113.823 1.00 11.16 ? 451  ILE D CG2 1 
ATOM   12485 C CD1 . ILE D 1 472 ? 82.980  124.967 112.238 1.00 11.16 ? 451  ILE D CD1 1 
ATOM   12486 N N   . LYS D 1 473 ? 87.411  126.770 111.894 1.00 11.52 ? 452  LYS D N   1 
ATOM   12487 C CA  . LYS D 1 473 ? 88.733  127.370 112.064 1.00 11.52 ? 452  LYS D CA  1 
ATOM   12488 C C   . LYS D 1 473 ? 89.269  127.062 113.463 1.00 11.52 ? 452  LYS D C   1 
ATOM   12489 O O   . LYS D 1 473 ? 89.463  127.940 114.302 1.00 11.52 ? 452  LYS D O   1 
ATOM   12490 C CB  . LYS D 1 473 ? 88.665  128.874 111.822 1.00 11.52 ? 452  LYS D CB  1 
ATOM   12491 C CG  . LYS D 1 473 ? 88.482  129.315 110.370 1.00 11.52 ? 452  LYS D CG  1 
ATOM   12492 C CD  . LYS D 1 473 ? 87.062  129.049 109.895 1.00 11.52 ? 452  LYS D CD  1 
ATOM   12493 C CE  . LYS D 1 473 ? 86.043  129.755 110.779 1.00 11.52 ? 452  LYS D CE  1 
ATOM   12494 N NZ  . LYS D 1 473 ? 84.641  129.414 110.419 1.00 11.52 ? 452  LYS D NZ  1 
ATOM   12495 N N   . ALA D 1 474 ? 89.494  125.775 113.709 1.00 13.24 ? 453  ALA D N   1 
ATOM   12496 C CA  . ALA D 1 474 ? 89.984  125.301 114.993 1.00 13.24 ? 453  ALA D CA  1 
ATOM   12497 C C   . ALA D 1 474 ? 90.920  124.125 114.753 1.00 13.24 ? 453  ALA D C   1 
ATOM   12498 O O   . ALA D 1 474 ? 91.123  123.688 113.617 1.00 13.24 ? 453  ALA D O   1 
ATOM   12499 C CB  . ALA D 1 474 ? 88.825  124.918 115.916 1.00 13.24 ? 453  ALA D CB  1 
ATOM   12500 N N   . GLY D 1 475 ? 91.494  123.604 115.835 1.00 13.21 ? 454  GLY D N   1 
ATOM   12501 C CA  . GLY D 1 475 ? 92.466  122.534 115.748 1.00 13.21 ? 454  GLY D CA  1 
ATOM   12502 C C   . GLY D 1 475 ? 92.004  121.161 116.180 1.00 13.21 ? 454  GLY D C   1 
ATOM   12503 O O   . GLY D 1 475 ? 92.826  120.238 116.219 1.00 13.21 ? 454  GLY D O   1 
ATOM   12504 N N   . ARG D 1 476 ? 90.729  120.982 116.507 1.00 12.74 ? 455  ARG D N   1 
ATOM   12505 C CA  . ARG D 1 476 ? 90.245  119.684 116.971 1.00 12.74 ? 455  ARG D CA  1 
ATOM   12506 C C   . ARG D 1 476 ? 88.738  119.653 116.807 1.00 12.74 ? 455  ARG D C   1 
ATOM   12507 O O   . ARG D 1 476 ? 88.036  120.447 117.436 1.00 12.74 ? 455  ARG D O   1 
ATOM   12508 C CB  . ARG D 1 476 ? 90.642  119.443 118.428 1.00 12.74 ? 455  ARG D CB  1 
ATOM   12509 C CG  . ARG D 1 476 ? 89.993  118.225 119.070 1.00 12.74 ? 455  ARG D CG  1 
ATOM   12510 C CD  . ARG D 1 476 ? 90.268  116.929 118.311 1.00 12.74 ? 455  ARG D CD  1 
ATOM   12511 N NE  . ARG D 1 476 ? 91.695  116.679 118.123 1.00 12.74 ? 455  ARG D NE  1 
ATOM   12512 C CZ  . ARG D 1 476 ? 92.453  115.988 118.967 1.00 12.74 ? 455  ARG D CZ  1 
ATOM   12513 N NH1 . ARG D 1 476 ? 91.922  115.467 120.063 1.00 12.74 ? 455  ARG D NH1 1 
ATOM   12514 N NH2 . ARG D 1 476 ? 93.742  115.817 118.713 1.00 12.74 ? 455  ARG D NH2 1 
ATOM   12515 N N   . VAL D 1 477 ? 88.242  118.747 115.971 1.00 9.26  ? 456  VAL D N   1 
ATOM   12516 C CA  . VAL D 1 477 ? 86.812  118.594 115.732 1.00 9.26  ? 456  VAL D CA  1 
ATOM   12517 C C   . VAL D 1 477 ? 86.415  117.187 116.149 1.00 9.26  ? 456  VAL D C   1 
ATOM   12518 O O   . VAL D 1 477 ? 87.020  116.208 115.698 1.00 9.26  ? 456  VAL D O   1 
ATOM   12519 C CB  . VAL D 1 477 ? 86.447  118.849 114.264 1.00 9.26  ? 456  VAL D CB  1 
ATOM   12520 C CG1 . VAL D 1 477 ? 84.945  118.878 114.098 1.00 9.26  ? 456  VAL D CG1 1 
ATOM   12521 C CG2 . VAL D 1 477 ? 87.062  120.146 113.788 1.00 9.26  ? 456  VAL D CG2 1 
ATOM   12522 N N   . TRP D 1 478 ? 85.407  117.083 117.006 1.00 11.47 ? 457  TRP D N   1 
ATOM   12523 C CA  . TRP D 1 478 ? 84.902  115.796 117.460 1.00 11.47 ? 457  TRP D CA  1 
ATOM   12524 C C   . TRP D 1 478 ? 83.581  115.505 116.760 1.00 11.47 ? 457  TRP D C   1 
ATOM   12525 O O   . TRP D 1 478 ? 82.634  116.288 116.868 1.00 11.47 ? 457  TRP D O   1 
ATOM   12526 C CB  . TRP D 1 478 ? 84.719  115.786 118.973 1.00 11.47 ? 457  TRP D CB  1 
ATOM   12527 C CG  . TRP D 1 478 ? 85.998  115.794 119.744 1.00 11.47 ? 457  TRP D CG  1 
ATOM   12528 C CD1 . TRP D 1 478 ? 86.898  114.777 119.846 1.00 11.47 ? 457  TRP D CD1 1 
ATOM   12529 C CD2 . TRP D 1 478 ? 86.506  116.860 120.553 1.00 11.47 ? 457  TRP D CD2 1 
ATOM   12530 N NE1 . TRP D 1 478 ? 87.942  115.147 120.654 1.00 11.47 ? 457  TRP D NE1 1 
ATOM   12531 C CE2 . TRP D 1 478 ? 87.725  116.422 121.103 1.00 11.47 ? 457  TRP D CE2 1 
ATOM   12532 C CE3 . TRP D 1 478 ? 86.051  118.146 120.861 1.00 11.47 ? 457  TRP D CE3 1 
ATOM   12533 C CZ2 . TRP D 1 478 ? 88.493  117.220 121.945 1.00 11.47 ? 457  TRP D CZ2 1 
ATOM   12534 C CZ3 . TRP D 1 478 ? 86.816  118.937 121.692 1.00 11.47 ? 457  TRP D CZ3 1 
ATOM   12535 C CH2 . TRP D 1 478 ? 88.024  118.473 122.224 1.00 11.47 ? 457  TRP D CH2 1 
ATOM   12536 N N   . THR D 1 479 ? 83.520  114.382 116.050 1.00 9.48  ? 458  THR D N   1 
ATOM   12537 C CA  . THR D 1 479 ? 82.334  113.979 115.304 1.00 9.48  ? 458  THR D CA  1 
ATOM   12538 C C   . THR D 1 479 ? 81.673  112.806 116.012 1.00 9.48  ? 458  THR D C   1 
ATOM   12539 O O   . THR D 1 479 ? 82.322  111.789 116.270 1.00 9.48  ? 458  THR D O   1 
ATOM   12540 C CB  . THR D 1 479 ? 82.687  113.598 113.871 1.00 9.48  ? 458  THR D CB  1 
ATOM   12541 O OG1 . THR D 1 479 ? 83.518  114.613 113.298 1.00 9.48  ? 458  THR D OG1 1 
ATOM   12542 C CG2 . THR D 1 479 ? 81.431  113.460 113.049 1.00 9.48  ? 458  THR D CG2 1 
ATOM   12543 N N   . ASN D 1 480 ? 80.387  112.953 116.323 1.00 12.13 ? 459  ASN D N   1 
ATOM   12544 C CA  . ASN D 1 480 ? 79.603  111.926 117.007 1.00 12.13 ? 459  ASN D CA  1 
ATOM   12545 C C   . ASN D 1 480 ? 80.247  111.485 118.318 1.00 12.13 ? 459  ASN D C   1 
ATOM   12546 O O   . ASN D 1 480 ? 80.026  110.361 118.778 1.00 12.13 ? 459  ASN D O   1 
ATOM   12547 C CB  . ASN D 1 480 ? 79.355  110.725 116.095 1.00 12.13 ? 459  ASN D CB  1 
ATOM   12548 C CG  . ASN D 1 480 ? 78.677  111.113 114.799 1.00 12.13 ? 459  ASN D CG  1 
ATOM   12549 O OD1 . ASN D 1 480 ? 77.979  112.121 114.731 1.00 12.13 ? 459  ASN D OD1 1 
ATOM   12550 N ND2 . ASN D 1 480 ? 78.884  110.316 113.759 1.00 12.13 ? 459  ASN D ND2 1 
ATOM   12551 N N   . CYS D 1 481 ? 81.035  112.363 118.930 1.00 13.53 ? 460  CYS D N   1 
ATOM   12552 C CA  . CYS D 1 481 ? 81.643  112.117 120.230 1.00 13.53 ? 460  CYS D CA  1 
ATOM   12553 C C   . CYS D 1 481 ? 82.132  113.451 120.775 1.00 13.53 ? 460  CYS D C   1 
ATOM   12554 O O   . CYS D 1 481 ? 81.924  114.503 120.167 1.00 13.53 ? 460  CYS D O   1 
ATOM   12555 C CB  . CYS D 1 481 ? 82.784  111.106 120.133 1.00 13.53 ? 460  CYS D CB  1 
ATOM   12556 S SG  . CYS D 1 481 ? 84.054  111.573 118.951 1.00 13.53 ? 460  CYS D SG  1 
ATOM   12557 N N   . TYR D 1 482 ? 82.781  113.401 121.933 1.00 18.50 ? 461  TYR D N   1 
ATOM   12558 C CA  . TYR D 1 482 ? 83.350  114.597 122.541 1.00 18.50 ? 461  TYR D CA  1 
ATOM   12559 C C   . TYR D 1 482 ? 84.332  114.236 123.649 1.00 18.50 ? 461  TYR D C   1 
ATOM   12560 O O   . TYR D 1 482 ? 83.973  113.565 124.615 1.00 18.50 ? 461  TYR D O   1 
ATOM   12561 C CB  . TYR D 1 482 ? 82.244  115.498 123.093 1.00 18.50 ? 461  TYR D CB  1 
ATOM   12562 C CG  . TYR D 1 482 ? 82.740  116.825 123.614 1.00 18.50 ? 461  TYR D CG  1 
ATOM   12563 C CD1 . TYR D 1 482 ? 83.162  117.821 122.743 1.00 18.50 ? 461  TYR D CD1 1 
ATOM   12564 C CD2 . TYR D 1 482 ? 82.783  117.083 124.976 1.00 18.50 ? 461  TYR D CD2 1 
ATOM   12565 C CE1 . TYR D 1 482 ? 83.617  119.034 123.216 1.00 18.50 ? 461  TYR D CE1 1 
ATOM   12566 C CE2 . TYR D 1 482 ? 83.235  118.291 125.458 1.00 18.50 ? 461  TYR D CE2 1 
ATOM   12567 C CZ  . TYR D 1 482 ? 83.650  119.265 124.576 1.00 18.50 ? 461  TYR D CZ  1 
ATOM   12568 O OH  . TYR D 1 482 ? 84.100  120.474 125.058 1.00 18.50 ? 461  TYR D OH  1 
ATOM   12569 N N   . THR D 1 503 ? 100.124 112.859 123.728 1.00 19.38 ? 482  THR D N   1 
ATOM   12570 C CA  . THR D 1 503 ? 99.066  112.261 122.926 1.00 19.38 ? 482  THR D CA  1 
ATOM   12571 C C   . THR D 1 503 ? 99.518  112.018 121.498 1.00 19.38 ? 482  THR D C   1 
ATOM   12572 O O   . THR D 1 503 ? 98.909  111.234 120.778 1.00 19.38 ? 482  THR D O   1 
ATOM   12573 C CB  . THR D 1 503 ? 97.808  113.149 122.894 1.00 19.38 ? 482  THR D CB  1 
ATOM   12574 O OG1 . THR D 1 503 ? 98.121  114.405 122.281 1.00 19.38 ? 482  THR D OG1 1 
ATOM   12575 C CG2 . THR D 1 503 ? 97.296  113.397 124.296 1.00 19.38 ? 482  THR D CG2 1 
ATOM   12576 N N   . HIS D 1 504 ? 100.589 112.693 121.085 1.00 16.85 ? 483  HIS D N   1 
ATOM   12577 C CA  . HIS D 1 504 ? 101.044 112.630 119.706 1.00 16.85 ? 483  HIS D CA  1 
ATOM   12578 C C   . HIS D 1 504 ? 102.560 112.535 119.669 1.00 16.85 ? 483  HIS D C   1 
ATOM   12579 O O   . HIS D 1 504 ? 103.250 113.028 120.564 1.00 16.85 ? 483  HIS D O   1 
ATOM   12580 C CB  . HIS D 1 504 ? 100.573 113.853 118.907 1.00 16.85 ? 483  HIS D CB  1 
ATOM   12581 C CG  . HIS D 1 504 ? 100.338 113.574 117.455 1.00 16.85 ? 483  HIS D CG  1 
ATOM   12582 N ND1 . HIS D 1 504 ? 101.222 112.857 116.679 1.00 16.85 ? 483  HIS D ND1 1 
ATOM   12583 C CD2 . HIS D 1 504 ? 99.312  113.911 116.639 1.00 16.85 ? 483  HIS D CD2 1 
ATOM   12584 C CE1 . HIS D 1 504 ? 100.753 112.766 115.448 1.00 16.85 ? 483  HIS D CE1 1 
ATOM   12585 N NE2 . HIS D 1 504 ? 99.594  113.397 115.397 1.00 16.85 ? 483  HIS D NE2 1 
ATOM   12586 N N   . LYS D 1 505 ? 103.071 111.896 118.613 1.00 12.17 ? 484  LYS D N   1 
ATOM   12587 C CA  . LYS D 1 505 ? 104.511 111.780 118.425 1.00 12.17 ? 484  LYS D CA  1 
ATOM   12588 C C   . LYS D 1 505 ? 105.183 113.140 118.341 1.00 12.17 ? 484  LYS D C   1 
ATOM   12589 O O   . LYS D 1 505 ? 106.361 113.275 118.689 1.00 12.17 ? 484  LYS D O   1 
ATOM   12590 C CB  . LYS D 1 505 ? 104.811 110.986 117.153 1.00 12.17 ? 484  LYS D CB  1 
ATOM   12591 C CG  . LYS D 1 505 ? 104.048 109.687 117.029 1.00 12.17 ? 484  LYS D CG  1 
ATOM   12592 C CD  . LYS D 1 505 ? 104.234 109.080 115.654 1.00 12.17 ? 484  LYS D CD  1 
ATOM   12593 C CE  . LYS D 1 505 ? 105.636 108.539 115.479 1.00 12.17 ? 484  LYS D CE  1 
ATOM   12594 N NZ  . LYS D 1 505 ? 105.742 107.692 114.266 1.00 12.17 ? 484  LYS D NZ  1 
ATOM   12595 N N   . MET D 1 506 ? 104.451 114.161 117.891 1.00 17.57 ? 485  MET D N   1 
ATOM   12596 C CA  . MET D 1 506 ? 105.026 115.486 117.697 1.00 17.57 ? 485  MET D CA  1 
ATOM   12597 C C   . MET D 1 506 ? 105.478 116.129 118.999 1.00 17.57 ? 485  MET D C   1 
ATOM   12598 O O   . MET D 1 506 ? 106.177 117.146 118.953 1.00 17.57 ? 485  MET D O   1 
ATOM   12599 C CB  . MET D 1 506 ? 104.018 116.392 116.994 1.00 17.57 ? 485  MET D CB  1 
ATOM   12600 C CG  . MET D 1 506 ? 103.532 115.843 115.666 1.00 17.57 ? 485  MET D CG  1 
ATOM   12601 S SD  . MET D 1 506 ? 104.657 116.219 114.310 1.00 17.57 ? 485  MET D SD  1 
ATOM   12602 C CE  . MET D 1 506 ? 103.950 117.744 113.693 1.00 17.57 ? 485  MET D CE  1 
ATOM   12603 N N   . MET D 1 507 ? 105.084 115.585 120.149 1.00 13.99 ? 486  MET D N   1 
ATOM   12604 C CA  . MET D 1 507 ? 105.655 116.043 121.408 1.00 13.99 ? 486  MET D CA  1 
ATOM   12605 C C   . MET D 1 507 ? 107.127 115.668 121.521 1.00 13.99 ? 486  MET D C   1 
ATOM   12606 O O   . MET D 1 507 ? 107.942 116.479 121.971 1.00 13.99 ? 486  MET D O   1 
ATOM   12607 C CB  . MET D 1 507 ? 104.865 115.472 122.584 1.00 13.99 ? 486  MET D CB  1 
ATOM   12608 C CG  . MET D 1 507 ? 103.464 116.034 122.722 1.00 13.99 ? 486  MET D CG  1 
ATOM   12609 S SD  . MET D 1 507 ? 102.962 116.202 124.447 1.00 13.99 ? 486  MET D SD  1 
ATOM   12610 C CE  . MET D 1 507 ? 103.587 117.834 124.833 1.00 13.99 ? 486  MET D CE  1 
ATOM   12611 N N   . LEU D 1 508 ? 107.487 114.454 121.102 1.00 9.19  ? 487  LEU D N   1 
ATOM   12612 C CA  . LEU D 1 508 ? 108.867 114.001 121.236 1.00 9.19  ? 487  LEU D CA  1 
ATOM   12613 C C   . LEU D 1 508 ? 109.830 114.842 120.415 1.00 9.19  ? 487  LEU D C   1 
ATOM   12614 O O   . LEU D 1 508 ? 111.013 114.924 120.757 1.00 9.19  ? 487  LEU D O   1 
ATOM   12615 C CB  . LEU D 1 508 ? 108.981 112.534 120.822 1.00 9.19  ? 487  LEU D CB  1 
ATOM   12616 C CG  . LEU D 1 508 ? 110.352 111.879 120.964 1.00 9.19  ? 487  LEU D CG  1 
ATOM   12617 C CD1 . LEU D 1 508 ? 110.779 111.858 122.411 1.00 9.19  ? 487  LEU D CD1 1 
ATOM   12618 C CD2 . LEU D 1 508 ? 110.330 110.480 120.395 1.00 9.19  ? 487  LEU D CD2 1 
ATOM   12619 N N   . ASP D 1 509 ? 109.355 115.479 119.352 1.00 10.51 ? 488  ASP D N   1 
ATOM   12620 C CA  . ASP D 1 509 ? 110.188 116.331 118.524 1.00 10.51 ? 488  ASP D CA  1 
ATOM   12621 C C   . ASP D 1 509 ? 110.147 117.787 118.965 1.00 10.51 ? 488  ASP D C   1 
ATOM   12622 O O   . ASP D 1 509 ? 110.727 118.645 118.294 1.00 10.51 ? 488  ASP D O   1 
ATOM   12623 C CB  . ASP D 1 509 ? 109.768 116.206 117.062 1.00 10.51 ? 488  ASP D CB  1 
ATOM   12624 C CG  . ASP D 1 509 ? 110.300 114.940 116.411 1.00 10.51 ? 488  ASP D CG  1 
ATOM   12625 O OD1 . ASP D 1 509 ? 111.136 114.255 117.037 1.00 10.51 ? 488  ASP D OD1 1 
ATOM   12626 O OD2 . ASP D 1 509 ? 109.883 114.629 115.273 1.00 10.51 ? 488  ASP D OD2 1 
ATOM   12627 N N   . HIS D 1 510 ? 109.474 118.087 120.075 1.00 11.01 ? 489  HIS D N   1 
ATOM   12628 C CA  . HIS D 1 510 ? 109.466 119.435 120.624 1.00 11.01 ? 489  HIS D CA  1 
ATOM   12629 C C   . HIS D 1 510 ? 110.504 119.638 121.711 1.00 11.01 ? 489  HIS D C   1 
ATOM   12630 O O   . HIS D 1 510 ? 110.963 120.766 121.911 1.00 11.01 ? 489  HIS D O   1 
ATOM   12631 C CB  . HIS D 1 510 ? 108.080 119.778 121.178 1.00 11.01 ? 489  HIS D CB  1 
ATOM   12632 C CG  . HIS D 1 510 ? 107.167 120.390 120.165 1.00 11.01 ? 489  HIS D CG  1 
ATOM   12633 N ND1 . HIS D 1 510 ? 106.166 119.679 119.540 1.00 11.01 ? 489  HIS D ND1 1 
ATOM   12634 C CD2 . HIS D 1 510 ? 107.113 121.643 119.655 1.00 11.01 ? 489  HIS D CD2 1 
ATOM   12635 C CE1 . HIS D 1 510 ? 105.531 120.469 118.693 1.00 11.01 ? 489  HIS D CE1 1 
ATOM   12636 N NE2 . HIS D 1 510 ? 106.087 121.666 118.744 1.00 11.01 ? 489  HIS D NE2 1 
ATOM   12637 N N   . TYR D 1 511 ? 110.885 118.575 122.414 1.00 8.23  ? 490  TYR D N   1 
ATOM   12638 C CA  . TYR D 1 511 ? 111.961 118.620 123.393 1.00 8.23  ? 490  TYR D CA  1 
ATOM   12639 C C   . TYR D 1 511 ? 113.239 118.007 122.849 1.00 8.23  ? 490  TYR D C   1 
ATOM   12640 O O   . TYR D 1 511 ? 113.992 117.380 123.595 1.00 8.23  ? 490  TYR D O   1 
ATOM   12641 C CB  . TYR D 1 511 ? 111.553 117.912 124.683 1.00 8.23  ? 490  TYR D CB  1 
ATOM   12642 C CG  . TYR D 1 511 ? 110.181 118.267 125.185 1.00 8.23  ? 490  TYR D CG  1 
ATOM   12643 C CD1 . TYR D 1 511 ? 109.053 117.660 124.662 1.00 8.23  ? 490  TYR D CD1 1 
ATOM   12644 C CD2 . TYR D 1 511 ? 110.012 119.217 126.175 1.00 8.23  ? 490  TYR D CD2 1 
ATOM   12645 C CE1 . TYR D 1 511 ? 107.801 117.982 125.114 1.00 8.23  ? 490  TYR D CE1 1 
ATOM   12646 C CE2 . TYR D 1 511 ? 108.760 119.544 126.634 1.00 8.23  ? 490  TYR D CE2 1 
ATOM   12647 C CZ  . TYR D 1 511 ? 107.659 118.923 126.100 1.00 8.23  ? 490  TYR D CZ  1 
ATOM   12648 O OH  . TYR D 1 511 ? 106.404 119.245 126.547 1.00 8.23  ? 490  TYR D OH  1 
ATOM   12649 N N   . GLN D 1 512 ? 113.504 118.190 121.562 1.00 5.38  ? 491  GLN D N   1 
ATOM   12650 C CA  . GLN D 1 512 ? 114.543 117.428 120.893 1.00 5.38  ? 491  GLN D CA  1 
ATOM   12651 C C   . GLN D 1 512 ? 114.965 118.201 119.656 1.00 5.38  ? 491  GLN D C   1 
ATOM   12652 O O   . GLN D 1 512 ? 114.110 118.679 118.907 1.00 5.38  ? 491  GLN D O   1 
ATOM   12653 C CB  . GLN D 1 512 ? 114.008 116.044 120.526 1.00 5.38  ? 491  GLN D CB  1 
ATOM   12654 C CG  . GLN D 1 512 ? 115.022 115.037 120.083 1.00 5.38  ? 491  GLN D CG  1 
ATOM   12655 C CD  . GLN D 1 512 ? 114.378 113.703 119.804 1.00 5.38  ? 491  GLN D CD  1 
ATOM   12656 O OE1 . GLN D 1 512 ? 113.160 113.589 119.816 1.00 5.38  ? 491  GLN D OE1 1 
ATOM   12657 N NE2 . GLN D 1 512 ? 115.187 112.676 119.613 1.00 5.38  ? 491  GLN D NE2 1 
ATOM   12658 N N   . GLN D 1 513 ? 116.267 118.331 119.446 1.00 3.62  ? 492  GLN D N   1 
ATOM   12659 C CA  . GLN D 1 513 ? 116.798 119.157 118.374 1.00 3.62  ? 492  GLN D CA  1 
ATOM   12660 C C   . GLN D 1 513 ? 117.522 118.293 117.354 1.00 3.62  ? 492  GLN D C   1 
ATOM   12661 O O   . GLN D 1 513 ? 117.931 117.168 117.638 1.00 3.62  ? 492  GLN D O   1 
ATOM   12662 C CB  . GLN D 1 513 ? 117.746 120.223 118.925 1.00 3.62  ? 492  GLN D CB  1 
ATOM   12663 C CG  . GLN D 1 513 ? 118.996 119.654 119.553 1.00 3.62  ? 492  GLN D CG  1 
ATOM   12664 C CD  . GLN D 1 513 ? 119.876 120.721 120.141 1.00 3.62  ? 492  GLN D CD  1 
ATOM   12665 O OE1 . GLN D 1 513 ? 120.910 120.426 120.734 1.00 3.62  ? 492  GLN D OE1 1 
ATOM   12666 N NE2 . GLN D 1 513 ? 119.472 121.973 119.985 1.00 3.62  ? 492  GLN D NE2 1 
ATOM   12667 N N   . THR D 1 514 ? 117.679 118.833 116.156 1.00 3.14  ? 493  THR D N   1 
ATOM   12668 C CA  . THR D 1 514 ? 118.192 118.080 115.023 1.00 3.14  ? 493  THR D CA  1 
ATOM   12669 C C   . THR D 1 514 ? 119.617 118.514 114.720 1.00 3.14  ? 493  THR D C   1 
ATOM   12670 O O   . THR D 1 514 ? 119.886 119.708 114.565 1.00 3.14  ? 493  THR D O   1 
ATOM   12671 C CB  . THR D 1 514 ? 117.305 118.283 113.794 1.00 3.14  ? 493  THR D CB  1 
ATOM   12672 O OG1 . THR D 1 514 ? 115.973 117.843 114.090 1.00 3.14  ? 493  THR D OG1 1 
ATOM   12673 C CG2 . THR D 1 514 ? 117.836 117.491 112.611 1.00 3.14  ? 493  THR D CG2 1 
ATOM   12674 N N   . LYS D 1 515 ? 120.523 117.547 114.646 1.00 2.96  ? 494  LYS D N   1 
ATOM   12675 C CA  . LYS D 1 515 ? 121.887 117.786 114.191 1.00 2.96  ? 494  LYS D CA  1 
ATOM   12676 C C   . LYS D 1 515 ? 121.986 117.347 112.742 1.00 2.96  ? 494  LYS D C   1 
ATOM   12677 O O   . LYS D 1 515 ? 121.910 116.154 112.444 1.00 2.96  ? 494  LYS D O   1 
ATOM   12678 C CB  . LYS D 1 515 ? 122.907 117.042 115.048 1.00 2.96  ? 494  LYS D CB  1 
ATOM   12679 C CG  . LYS D 1 515 ? 124.338 117.170 114.537 1.00 2.96  ? 494  LYS D CG  1 
ATOM   12680 C CD  . LYS D 1 515 ? 124.831 118.604 114.530 1.00 2.96  ? 494  LYS D CD  1 
ATOM   12681 C CE  . LYS D 1 515 ? 125.017 119.144 115.931 1.00 2.96  ? 494  LYS D CE  1 
ATOM   12682 N NZ  . LYS D 1 515 ? 126.164 118.490 116.603 1.00 2.96  ? 494  LYS D NZ  1 
ATOM   12683 N N   . ASN D 1 516 ? 122.144 118.307 111.844 1.00 3.20  ? 495  ASN D N   1 
ATOM   12684 C CA  . ASN D 1 516 ? 122.350 118.009 110.439 1.00 3.20  ? 495  ASN D CA  1 
ATOM   12685 C C   . ASN D 1 516 ? 123.840 117.931 110.156 1.00 3.20  ? 495  ASN D C   1 
ATOM   12686 O O   . ASN D 1 516 ? 124.573 118.892 110.392 1.00 3.20  ? 495  ASN D O   1 
ATOM   12687 C CB  . ASN D 1 516 ? 121.696 119.070 109.559 1.00 3.20  ? 495  ASN D CB  1 
ATOM   12688 C CG  . ASN D 1 516 ? 121.794 118.742 108.095 1.00 3.20  ? 495  ASN D CG  1 
ATOM   12689 O OD1 . ASN D 1 516 ? 121.069 117.894 107.589 1.00 3.20  ? 495  ASN D OD1 1 
ATOM   12690 N ND2 . ASN D 1 516 ? 122.702 119.407 107.404 1.00 3.20  ? 495  ASN D ND2 1 
ATOM   12691 N N   . MET D 1 517 ? 124.281 116.784 109.657 1.00 2.91  ? 496  MET D N   1 
ATOM   12692 C CA  . MET D 1 517 ? 125.675 116.549 109.296 1.00 2.91  ? 496  MET D CA  1 
ATOM   12693 C C   . MET D 1 517 ? 125.711 116.247 107.807 1.00 2.91  ? 496  MET D C   1 
ATOM   12694 O O   . MET D 1 517 ? 125.313 115.162 107.384 1.00 2.91  ? 496  MET D O   1 
ATOM   12695 C CB  . MET D 1 517 ? 126.270 115.400 110.102 1.00 2.91  ? 496  MET D CB  1 
ATOM   12696 C CG  . MET D 1 517 ? 126.419 115.660 111.586 1.00 2.91  ? 496  MET D CG  1 
ATOM   12697 S SD  . MET D 1 517 ? 127.044 114.201 112.429 1.00 2.91  ? 496  MET D SD  1 
ATOM   12698 C CE  . MET D 1 517 ? 128.724 114.151 111.827 1.00 2.91  ? 496  MET D CE  1 
ATOM   12699 N N   . LEU D 1 518 ? 126.164 117.200 107.010 1.00 10.72 ? 497  LEU D N   1 
ATOM   12700 C CA  . LEU D 1 518 ? 126.327 116.981 105.583 1.00 10.72 ? 497  LEU D CA  1 
ATOM   12701 C C   . LEU D 1 518 ? 127.743 116.490 105.332 1.00 10.72 ? 497  LEU D C   1 
ATOM   12702 O O   . LEU D 1 518 ? 128.703 117.238 105.529 1.00 10.72 ? 497  LEU D O   1 
ATOM   12703 C CB  . LEU D 1 518 ? 126.052 118.259 104.797 1.00 10.72 ? 497  LEU D CB  1 
ATOM   12704 C CG  . LEU D 1 518 ? 126.051 118.084 103.278 1.00 10.72 ? 497  LEU D CG  1 
ATOM   12705 C CD1 . LEU D 1 518 ? 124.696 117.620 102.798 1.00 10.72 ? 497  LEU D CD1 1 
ATOM   12706 C CD2 . LEU D 1 518 ? 126.446 119.364 102.592 1.00 10.72 ? 497  LEU D CD2 1 
ATOM   12707 N N   . VAL D 1 519 ? 127.877 115.243 104.897 1.00 2.68  ? 498  VAL D N   1 
ATOM   12708 C CA  . VAL D 1 519 ? 129.172 114.610 104.711 1.00 2.68  ? 498  VAL D CA  1 
ATOM   12709 C C   . VAL D 1 519 ? 129.382 114.382 103.229 1.00 2.68  ? 498  VAL D C   1 
ATOM   12710 O O   . VAL D 1 519 ? 128.520 113.811 102.555 1.00 2.68  ? 498  VAL D O   1 
ATOM   12711 C CB  . VAL D 1 519 ? 129.279 113.283 105.479 1.00 2.68  ? 498  VAL D CB  1 
ATOM   12712 C CG1 . VAL D 1 519 ? 130.687 112.750 105.386 1.00 2.68  ? 498  VAL D CG1 1 
ATOM   12713 C CG2 . VAL D 1 519 ? 128.861 113.466 106.926 1.00 2.68  ? 498  VAL D CG2 1 
ATOM   12714 N N   . SER D 1 520 ? 130.529 114.818 102.728 1.00 2.55  ? 499  SER D N   1 
ATOM   12715 C CA  . SER D 1 520 ? 130.915 114.614 101.343 1.00 2.55  ? 499  SER D CA  1 
ATOM   12716 C C   . SER D 1 520 ? 132.010 113.564 101.290 1.00 2.55  ? 499  SER D C   1 
ATOM   12717 O O   . SER D 1 520 ? 133.016 113.673 101.997 1.00 2.55  ? 499  SER D O   1 
ATOM   12718 C CB  . SER D 1 520 ? 131.392 115.916 100.712 1.00 2.55  ? 499  SER D CB  1 
ATOM   12719 O OG  . SER D 1 520 ? 132.197 115.661 99.580  1.00 2.55  ? 499  SER D OG  1 
ATOM   12720 N N   . TYR D 1 521 ? 131.813 112.550 100.456 1.00 3.21  ? 500  TYR D N   1 
ATOM   12721 C CA  . TYR D 1 521 ? 132.713 111.411 100.395 1.00 3.21  ? 500  TYR D CA  1 
ATOM   12722 C C   . TYR D 1 521 ? 133.559 111.416 99.133  1.00 3.21  ? 500  TYR D C   1 
ATOM   12723 O O   . TYR D 1 521 ? 134.063 110.368 98.725  1.00 3.21  ? 500  TYR D O   1 
ATOM   12724 C CB  . TYR D 1 521 ? 131.917 110.115 100.495 1.00 3.21  ? 500  TYR D CB  1 
ATOM   12725 C CG  . TYR D 1 521 ? 131.177 109.960 101.798 1.00 3.21  ? 500  TYR D CG  1 
ATOM   12726 C CD1 . TYR D 1 521 ? 131.822 109.503 102.928 1.00 3.21  ? 500  TYR D CD1 1 
ATOM   12727 C CD2 . TYR D 1 521 ? 129.830 110.263 101.891 1.00 3.21  ? 500  TYR D CD2 1 
ATOM   12728 C CE1 . TYR D 1 521 ? 131.152 109.358 104.111 1.00 3.21  ? 500  TYR D CE1 1 
ATOM   12729 C CE2 . TYR D 1 521 ? 129.153 110.119 103.070 1.00 3.21  ? 500  TYR D CE2 1 
ATOM   12730 C CZ  . TYR D 1 521 ? 129.817 109.664 104.177 1.00 3.21  ? 500  TYR D CZ  1 
ATOM   12731 O OH  . TYR D 1 521 ? 129.146 109.517 105.364 1.00 3.21  ? 500  TYR D OH  1 
ATOM   12732 N N   . SER D 1 522 ? 133.722 112.560 98.517  1.00 8.66  ? 501  SER D N   1 
ATOM   12733 C CA  . SER D 1 522 ? 134.519 112.648 97.307  1.00 8.66  ? 501  SER D CA  1 
ATOM   12734 C C   . SER D 1 522 ? 135.901 113.189 97.632  1.00 8.66  ? 501  SER D C   1 
ATOM   12735 O O   . SER D 1 522 ? 136.015 114.199 98.339  1.00 8.66  ? 501  SER D O   1 
ATOM   12736 C CB  . SER D 1 522 ? 133.835 113.548 96.284  1.00 8.66  ? 501  SER D CB  1 
ATOM   12737 O OG  . SER D 1 522 ? 134.499 113.491 95.034  1.00 8.66  ? 501  SER D OG  1 
ATOM   12738 N N   . PRO D 1 523 ? 136.964 112.556 97.150  1.00 13.78 ? 502  PRO D N   1 
ATOM   12739 C CA  . PRO D 1 523 ? 138.308 113.075 97.415  1.00 13.78 ? 502  PRO D CA  1 
ATOM   12740 C C   . PRO D 1 523 ? 138.704 114.178 96.445  1.00 13.78 ? 502  PRO D C   1 
ATOM   12741 O O   . PRO D 1 523 ? 139.505 115.052 96.784  1.00 13.78 ? 502  PRO D O   1 
ATOM   12742 C CB  . PRO D 1 523 ? 139.185 111.832 97.253  1.00 13.78 ? 502  PRO D CB  1 
ATOM   12743 C CG  . PRO D 1 523 ? 138.478 111.030 96.204  1.00 13.78 ? 502  PRO D CG  1 
ATOM   12744 C CD  . PRO D 1 523 ? 137.000 111.355 96.295  1.00 13.78 ? 502  PRO D CD  1 
ATOM   12745 N N   . LYS D 1 524 ? 138.145 114.148 95.241  1.00 18.55 ? 503  LYS D N   1 
ATOM   12746 C CA  . LYS D 1 524 ? 138.433 115.137 94.216  1.00 18.55 ? 503  LYS D CA  1 
ATOM   12747 C C   . LYS D 1 524 ? 137.530 116.353 94.374  1.00 18.55 ? 503  LYS D C   1 
ATOM   12748 O O   . LYS D 1 524 ? 136.529 116.332 95.091  1.00 18.55 ? 503  LYS D O   1 
ATOM   12749 C CB  . LYS D 1 524 ? 138.257 114.531 92.825  1.00 18.55 ? 503  LYS D CB  1 
ATOM   12750 C CG  . LYS D 1 524 ? 138.875 113.159 92.660  1.00 18.55 ? 503  LYS D CG  1 
ATOM   12751 C CD  . LYS D 1 524 ? 138.479 112.547 91.331  1.00 18.55 ? 503  LYS D CD  1 
ATOM   12752 C CE  . LYS D 1 524 ? 137.070 111.980 91.383  1.00 18.55 ? 503  LYS D CE  1 
ATOM   12753 N NZ  . LYS D 1 524 ? 137.044 110.575 91.875  1.00 18.55 ? 503  LYS D NZ  1 
ATOM   12754 N N   . LYS D 1 525 ? 137.897 117.427 93.685  1.00 20.10 ? 504  LYS D N   1 
ATOM   12755 C CA  . LYS D 1 525 ? 137.087 118.639 93.668  1.00 20.10 ? 504  LYS D CA  1 
ATOM   12756 C C   . LYS D 1 525 ? 136.953 119.175 92.247  1.00 20.10 ? 504  LYS D C   1 
ATOM   12757 O O   . LYS D 1 525 ? 136.089 120.003 91.967  1.00 20.10 ? 504  LYS D O   1 
ATOM   12758 C CB  . LYS D 1 525 ? 137.686 119.707 94.590  1.00 20.10 ? 504  LYS D CB  1 
ATOM   12759 C CG  . LYS D 1 525 ? 139.115 120.104 94.254  1.00 20.10 ? 504  LYS D CG  1 
ATOM   12760 C CD  . LYS D 1 525 ? 139.165 121.356 93.399  1.00 20.10 ? 504  LYS D CD  1 
ATOM   12761 C CE  . LYS D 1 525 ? 140.589 121.724 93.046  1.00 20.10 ? 504  LYS D CE  1 
ATOM   12762 N NZ  . LYS D 1 525 ? 140.639 122.935 92.190  1.00 20.10 ? 504  LYS D NZ  1 
HETATM 12763 K K   . K   E 2 .   ? 95.301  95.742  69.770  1.00 30.00 ? 1001 K   A K   1 
HETATM 12764 K K   . K   F 2 .   ? 117.750 69.386  120.693 1.00 30.00 ? 1001 K   B K   1 
# 
