data_9FKL
# 
_entry.id   9FKL 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9FKL         pdb_00009fkl 10.2210/pdb9fkl/pdb 
WWPDB D_1292139090 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9FKL 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gil2@mail.huji.ac.il 
_pdbx_contact_author.name_first         Gil 
_pdbx_contact_author.name_last          Shoham 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2491-3715 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hadad, N.'    1 ? 
'Chmelnik, O.' 2 ? 
'Dessau, M.'   3 ? 
'Shoham, Y.'   4 ? 
'Shoham, G.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;The structure of glycosynthase IXT6 (E241G mutant), the intracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylohexaose-F molecules
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hadad, N.'    1 ? 
primary 'Chmelnik, O.' 2 ? 
primary 'Dessau, M.'   3 ? 
primary 'Shoham, Y.'   4 ? 
primary 'Shoham, G.'   5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man Beta-xylanase 38622.805 2   3.2.1.8 ? ? ? 
2 branched syn 'beta-D-xylopyranose-(1-4)-1-fluoro-D-xylopyranose' 284.236   1   ?       ? ? ? 
3 branched syn 
;beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-1-fluoro-D-xylopyranose
;
812.695   1   ?       ? ? ? 
4 water    nat water 18.015    497 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MNSSLPSLRDVFANDFRIGAAVNPVTIEMQKQLLIDHVNSITAENHMKFEHLQPEEGKFTFQEADRIVDFACSHRMAVRG
HTLVWHNQTPDWVFQDGQGHFVSRDVLLERMKCHISTVVRRYKGKIYCWDVINEAVADEGNELLRPSKWRQIIGDDFMEQ
AFLYAYEADPDALLFYNDYNECFPEKREKIFALVKSLRDKGIPIHGIGMQAHWSLTRPSLDEIRAAIERYASLGVVLHIT
GLDVSMFEFHDRRTDLAAPTSEMIERQAERYGQIFALFKEYRDVIQSVTFWGIADDHTWLDNFPVHGRKNWPLLFDEQHK
PKPAFWRAVSV
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MNSSLPSLRDVFANDFRIGAAVNPVTIEMQKQLLIDHVNSITAENHMKFEHLQPEEGKFTFQEADRIVDFACSHRMAVRG
HTLVWHNQTPDWVFQDGQGHFVSRDVLLERMKCHISTVVRRYKGKIYCWDVINEAVADEGNELLRPSKWRQIIGDDFMEQ
AFLYAYEADPDALLFYNDYNECFPEKREKIFALVKSLRDKGIPIHGIGMQAHWSLTRPSLDEIRAAIERYASLGVVLHIT
GLDVSMFEFHDRRTDLAAPTSEMIERQAERYGQIFALFKEYRDVIQSVTFWGIADDHTWLDNFPVHGRKNWPLLFDEQHK
PKPAFWRAVSV
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASN n 
1 3   SER n 
1 4   SER n 
1 5   LEU n 
1 6   PRO n 
1 7   SER n 
1 8   LEU n 
1 9   ARG n 
1 10  ASP n 
1 11  VAL n 
1 12  PHE n 
1 13  ALA n 
1 14  ASN n 
1 15  ASP n 
1 16  PHE n 
1 17  ARG n 
1 18  ILE n 
1 19  GLY n 
1 20  ALA n 
1 21  ALA n 
1 22  VAL n 
1 23  ASN n 
1 24  PRO n 
1 25  VAL n 
1 26  THR n 
1 27  ILE n 
1 28  GLU n 
1 29  MET n 
1 30  GLN n 
1 31  LYS n 
1 32  GLN n 
1 33  LEU n 
1 34  LEU n 
1 35  ILE n 
1 36  ASP n 
1 37  HIS n 
1 38  VAL n 
1 39  ASN n 
1 40  SER n 
1 41  ILE n 
1 42  THR n 
1 43  ALA n 
1 44  GLU n 
1 45  ASN n 
1 46  HIS n 
1 47  MET n 
1 48  LYS n 
1 49  PHE n 
1 50  GLU n 
1 51  HIS n 
1 52  LEU n 
1 53  GLN n 
1 54  PRO n 
1 55  GLU n 
1 56  GLU n 
1 57  GLY n 
1 58  LYS n 
1 59  PHE n 
1 60  THR n 
1 61  PHE n 
1 62  GLN n 
1 63  GLU n 
1 64  ALA n 
1 65  ASP n 
1 66  ARG n 
1 67  ILE n 
1 68  VAL n 
1 69  ASP n 
1 70  PHE n 
1 71  ALA n 
1 72  CYS n 
1 73  SER n 
1 74  HIS n 
1 75  ARG n 
1 76  MET n 
1 77  ALA n 
1 78  VAL n 
1 79  ARG n 
1 80  GLY n 
1 81  HIS n 
1 82  THR n 
1 83  LEU n 
1 84  VAL n 
1 85  TRP n 
1 86  HIS n 
1 87  ASN n 
1 88  GLN n 
1 89  THR n 
1 90  PRO n 
1 91  ASP n 
1 92  TRP n 
1 93  VAL n 
1 94  PHE n 
1 95  GLN n 
1 96  ASP n 
1 97  GLY n 
1 98  GLN n 
1 99  GLY n 
1 100 HIS n 
1 101 PHE n 
1 102 VAL n 
1 103 SER n 
1 104 ARG n 
1 105 ASP n 
1 106 VAL n 
1 107 LEU n 
1 108 LEU n 
1 109 GLU n 
1 110 ARG n 
1 111 MET n 
1 112 LYS n 
1 113 CYS n 
1 114 HIS n 
1 115 ILE n 
1 116 SER n 
1 117 THR n 
1 118 VAL n 
1 119 VAL n 
1 120 ARG n 
1 121 ARG n 
1 122 TYR n 
1 123 LYS n 
1 124 GLY n 
1 125 LYS n 
1 126 ILE n 
1 127 TYR n 
1 128 CYS n 
1 129 TRP n 
1 130 ASP n 
1 131 VAL n 
1 132 ILE n 
1 133 ASN n 
1 134 GLU n 
1 135 ALA n 
1 136 VAL n 
1 137 ALA n 
1 138 ASP n 
1 139 GLU n 
1 140 GLY n 
1 141 ASN n 
1 142 GLU n 
1 143 LEU n 
1 144 LEU n 
1 145 ARG n 
1 146 PRO n 
1 147 SER n 
1 148 LYS n 
1 149 TRP n 
1 150 ARG n 
1 151 GLN n 
1 152 ILE n 
1 153 ILE n 
1 154 GLY n 
1 155 ASP n 
1 156 ASP n 
1 157 PHE n 
1 158 MET n 
1 159 GLU n 
1 160 GLN n 
1 161 ALA n 
1 162 PHE n 
1 163 LEU n 
1 164 TYR n 
1 165 ALA n 
1 166 TYR n 
1 167 GLU n 
1 168 ALA n 
1 169 ASP n 
1 170 PRO n 
1 171 ASP n 
1 172 ALA n 
1 173 LEU n 
1 174 LEU n 
1 175 PHE n 
1 176 TYR n 
1 177 ASN n 
1 178 ASP n 
1 179 TYR n 
1 180 ASN n 
1 181 GLU n 
1 182 CYS n 
1 183 PHE n 
1 184 PRO n 
1 185 GLU n 
1 186 LYS n 
1 187 ARG n 
1 188 GLU n 
1 189 LYS n 
1 190 ILE n 
1 191 PHE n 
1 192 ALA n 
1 193 LEU n 
1 194 VAL n 
1 195 LYS n 
1 196 SER n 
1 197 LEU n 
1 198 ARG n 
1 199 ASP n 
1 200 LYS n 
1 201 GLY n 
1 202 ILE n 
1 203 PRO n 
1 204 ILE n 
1 205 HIS n 
1 206 GLY n 
1 207 ILE n 
1 208 GLY n 
1 209 MET n 
1 210 GLN n 
1 211 ALA n 
1 212 HIS n 
1 213 TRP n 
1 214 SER n 
1 215 LEU n 
1 216 THR n 
1 217 ARG n 
1 218 PRO n 
1 219 SER n 
1 220 LEU n 
1 221 ASP n 
1 222 GLU n 
1 223 ILE n 
1 224 ARG n 
1 225 ALA n 
1 226 ALA n 
1 227 ILE n 
1 228 GLU n 
1 229 ARG n 
1 230 TYR n 
1 231 ALA n 
1 232 SER n 
1 233 LEU n 
1 234 GLY n 
1 235 VAL n 
1 236 VAL n 
1 237 LEU n 
1 238 HIS n 
1 239 ILE n 
1 240 THR n 
1 241 GLY n 
1 242 LEU n 
1 243 ASP n 
1 244 VAL n 
1 245 SER n 
1 246 MET n 
1 247 PHE n 
1 248 GLU n 
1 249 PHE n 
1 250 HIS n 
1 251 ASP n 
1 252 ARG n 
1 253 ARG n 
1 254 THR n 
1 255 ASP n 
1 256 LEU n 
1 257 ALA n 
1 258 ALA n 
1 259 PRO n 
1 260 THR n 
1 261 SER n 
1 262 GLU n 
1 263 MET n 
1 264 ILE n 
1 265 GLU n 
1 266 ARG n 
1 267 GLN n 
1 268 ALA n 
1 269 GLU n 
1 270 ARG n 
1 271 TYR n 
1 272 GLY n 
1 273 GLN n 
1 274 ILE n 
1 275 PHE n 
1 276 ALA n 
1 277 LEU n 
1 278 PHE n 
1 279 LYS n 
1 280 GLU n 
1 281 TYR n 
1 282 ARG n 
1 283 ASP n 
1 284 VAL n 
1 285 ILE n 
1 286 GLN n 
1 287 SER n 
1 288 VAL n 
1 289 THR n 
1 290 PHE n 
1 291 TRP n 
1 292 GLY n 
1 293 ILE n 
1 294 ALA n 
1 295 ASP n 
1 296 ASP n 
1 297 HIS n 
1 298 THR n 
1 299 TRP n 
1 300 LEU n 
1 301 ASP n 
1 302 ASN n 
1 303 PHE n 
1 304 PRO n 
1 305 VAL n 
1 306 HIS n 
1 307 GLY n 
1 308 ARG n 
1 309 LYS n 
1 310 ASN n 
1 311 TRP n 
1 312 PRO n 
1 313 LEU n 
1 314 LEU n 
1 315 PHE n 
1 316 ASP n 
1 317 GLU n 
1 318 GLN n 
1 319 HIS n 
1 320 LYS n 
1 321 PRO n 
1 322 LYS n 
1 323 PRO n 
1 324 ALA n 
1 325 PHE n 
1 326 TRP n 
1 327 ARG n 
1 328 ALA n 
1 329 VAL n 
1 330 SER n 
1 331 VAL n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   331 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 xynA2 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Geobacillus proteiniphilus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     860353 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 '[][&lt;C5O3F1&gt;]{[(1+1)][b-D-Xylp]{}}'                                                                             LINUCS 
PDB-CARE ? 
2 3 '[][&lt;C5O3F1&gt;]{[(1+1)][b-D-Xylp]{[(4+1)][b-D-Xylp]{[(4+1)][b-D-Xylp]{[(4+1)][b-D-Xylp]{[(4+1)][b-D-Xylp]{}}}}}}' LINUCS 
PDB-CARE ? 
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 XYP C1 O1 1 A1ID6 O4 HO4 sing ? 
2 3 2 XYP C1 O1 1 A1ID6 O4 HO4 sing ? 
3 3 3 XYP C1 O1 2 XYP   O4 HO4 sing ? 
4 3 4 XYP C1 O1 3 XYP   O4 HO4 sing ? 
5 3 5 XYP C1 O1 4 XYP   O4 HO4 sing ? 
6 3 6 XYP C1 O1 5 XYP   O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1ID6 D-saccharide                 . 1-fluoro-D-xylopyranose ?                                 'C5 H9 F O4'     152.121 
ALA   'L-peptide linking'          y ALANINE                 ?                                 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking'          y ARGININE                ?                                 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking'          y ASPARAGINE              ?                                 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID'         ?                                 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking'          y CYSTEINE                ?                                 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking'          y GLUTAMINE               ?                                 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID'         ?                                 'C5 H9 N O4'     147.129 
GLY   'peptide linking'            y GLYCINE                 ?                                 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking'          y HISTIDINE               ?                                 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer                  . WATER                   ?                                 'H2 O'           18.015  
ILE   'L-peptide linking'          y ISOLEUCINE              ?                                 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking'          y LEUCINE                 ?                                 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking'          y LYSINE                  ?                                 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking'          y METHIONINE              ?                                 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking'          y PHENYLALANINE           ?                                 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking'          y PROLINE                 ?                                 'C5 H9 N O2'     115.130 
SER   'L-peptide linking'          y SERINE                  ?                                 'C3 H7 N O3'     105.093 
THR   'L-peptide linking'          y THREONINE               ?                                 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN              ?                                 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking'          y TYROSINE                ?                                 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking'          y VALINE                  ?                                 'C5 H11 N O2'    117.146 
XYP   'D-saccharide, beta linking' . beta-D-xylopyranose     'beta-D-xylose; D-xylose; xylose' 'C5 H10 O5'      150.130 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
XYP 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DXylpb           
XYP 'COMMON NAME'                         GMML     1.0 b-D-xylopyranose 
XYP 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Xylp         
XYP 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Xyl              
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASN 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   3   SER SER A . n 
A 1 4   SER 4   4   4   SER SER A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ARG 9   9   9   ARG ARG A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  PHE 12  12  12  PHE PHE A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  ASN 14  14  14  ASN ASN A . n 
A 1 15  ASP 15  15  15  ASP ASP A . n 
A 1 16  PHE 16  16  16  PHE PHE A . n 
A 1 17  ARG 17  17  17  ARG ARG A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ASN 23  23  23  ASN ASN A . n 
A 1 24  PRO 24  24  24  PRO PRO A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  ILE 27  27  27  ILE ILE A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  MET 29  29  29  MET MET A . n 
A 1 30  GLN 30  30  30  GLN GLN A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  GLN 32  32  32  GLN GLN A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  LEU 34  34  34  LEU LEU A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  ASP 36  36  36  ASP ASP A . n 
A 1 37  HIS 37  37  37  HIS HIS A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  ILE 41  41  41  ILE ILE A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  ALA 43  43  43  ALA ALA A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ASN 45  45  45  ASN ASN A . n 
A 1 46  HIS 46  46  46  HIS HIS A . n 
A 1 47  MET 47  47  47  MET MET A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  PHE 49  49  49  PHE PHE A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  HIS 51  51  51  HIS HIS A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  GLN 53  53  53  GLN GLN A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  GLU 56  56  56  GLU GLU A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  LYS 58  58  58  LYS LYS A . n 
A 1 59  PHE 59  59  59  PHE PHE A . n 
A 1 60  THR 60  60  60  THR THR A . n 
A 1 61  PHE 61  61  61  PHE PHE A . n 
A 1 62  GLN 62  62  62  GLN GLN A . n 
A 1 63  GLU 63  63  63  GLU GLU A . n 
A 1 64  ALA 64  64  64  ALA ALA A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  ASP 69  69  69  ASP ASP A . n 
A 1 70  PHE 70  70  70  PHE PHE A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  CYS 72  72  72  CYS CYS A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  HIS 74  74  74  HIS HIS A . n 
A 1 75  ARG 75  75  75  ARG ARG A . n 
A 1 76  MET 76  76  76  MET MET A . n 
A 1 77  ALA 77  77  77  ALA ALA A . n 
A 1 78  VAL 78  78  78  VAL VAL A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  GLY 80  80  80  GLY GLY A . n 
A 1 81  HIS 81  81  81  HIS HIS A . n 
A 1 82  THR 82  82  82  THR THR A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  TRP 85  85  85  TRP TRP A . n 
A 1 86  HIS 86  86  86  HIS HIS A . n 
A 1 87  ASN 87  87  87  ASN ASN A . n 
A 1 88  GLN 88  88  88  GLN GLN A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  PRO 90  90  90  PRO PRO A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  TRP 92  92  92  TRP TRP A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  PHE 94  94  94  PHE PHE A . n 
A 1 95  GLN 95  95  95  GLN GLN A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 HIS 100 100 100 HIS HIS A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 SER 103 103 103 SER SER A . n 
A 1 104 ARG 104 104 104 ARG ARG A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 ARG 110 110 110 ARG ARG A . n 
A 1 111 MET 111 111 111 MET MET A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 CYS 113 113 113 CYS CYS A . n 
A 1 114 HIS 114 114 114 HIS HIS A . n 
A 1 115 ILE 115 115 115 ILE ILE A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 THR 117 117 117 THR THR A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 VAL 119 119 119 VAL VAL A . n 
A 1 120 ARG 120 120 120 ARG ARG A . n 
A 1 121 ARG 121 121 121 ARG ARG A . n 
A 1 122 TYR 122 122 122 TYR TYR A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 LYS 125 125 125 LYS LYS A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 TYR 127 127 127 TYR TYR A . n 
A 1 128 CYS 128 128 128 CYS CYS A . n 
A 1 129 TRP 129 129 129 TRP TRP A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 ILE 132 132 132 ILE ILE A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 GLU 134 134 134 GLU GLU A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 ASN 141 141 141 ASN ASN A . n 
A 1 142 GLU 142 142 142 GLU GLU A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 ARG 145 145 145 ARG ARG A . n 
A 1 146 PRO 146 146 146 PRO PRO A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 TRP 149 149 149 TRP TRP A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 GLN 151 151 151 GLN GLN A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ILE 153 153 153 ILE ILE A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 ASP 156 156 156 ASP ASP A . n 
A 1 157 PHE 157 157 157 PHE PHE A . n 
A 1 158 MET 158 158 158 MET MET A . n 
A 1 159 GLU 159 159 159 GLU GLU A . n 
A 1 160 GLN 160 160 160 GLN GLN A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 PHE 162 162 162 PHE PHE A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 TYR 164 164 164 TYR TYR A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 TYR 166 166 166 TYR TYR A . n 
A 1 167 GLU 167 167 167 GLU GLU A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 ASP 169 169 169 ASP ASP A . n 
A 1 170 PRO 170 170 170 PRO PRO A . n 
A 1 171 ASP 171 171 171 ASP ASP A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 PHE 175 175 175 PHE PHE A . n 
A 1 176 TYR 176 176 176 TYR TYR A . n 
A 1 177 ASN 177 177 177 ASN ASN A . n 
A 1 178 ASP 178 178 178 ASP ASP A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 CYS 182 182 182 CYS CYS A . n 
A 1 183 PHE 183 183 183 PHE PHE A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 LYS 186 186 186 LYS LYS A . n 
A 1 187 ARG 187 187 187 ARG ARG A . n 
A 1 188 GLU 188 188 188 GLU GLU A . n 
A 1 189 LYS 189 189 189 LYS LYS A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 PHE 191 191 191 PHE PHE A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 ASP 199 199 199 ASP ASP A . n 
A 1 200 LYS 200 200 200 LYS LYS A . n 
A 1 201 GLY 201 201 201 GLY GLY A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 ILE 204 204 204 ILE ILE A . n 
A 1 205 HIS 205 205 205 HIS HIS A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 ILE 207 207 207 ILE ILE A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 MET 209 209 209 MET MET A . n 
A 1 210 GLN 210 210 210 GLN GLN A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 HIS 212 212 212 HIS HIS A . n 
A 1 213 TRP 213 213 213 TRP TRP A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 THR 216 216 216 THR THR A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 GLU 222 222 222 GLU GLU A . n 
A 1 223 ILE 223 223 223 ILE ILE A . n 
A 1 224 ARG 224 224 224 ARG ARG A . n 
A 1 225 ALA 225 225 225 ALA ALA A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 ILE 227 227 227 ILE ILE A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 TYR 230 230 230 TYR TYR A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 SER 232 232 232 SER SER A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 GLY 234 234 234 GLY GLY A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 ILE 239 239 239 ILE ILE A . n 
A 1 240 THR 240 240 240 THR THR A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 ASP 243 243 243 ASP ASP A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 SER 245 245 245 SER SER A . n 
A 1 246 MET 246 246 246 MET MET A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 PHE 249 249 249 PHE PHE A . n 
A 1 250 HIS 250 250 250 HIS HIS A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 ARG 252 252 252 ARG ARG A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 THR 254 254 254 THR THR A . n 
A 1 255 ASP 255 255 255 ASP ASP A . n 
A 1 256 LEU 256 256 256 LEU LEU A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 PRO 259 259 259 PRO PRO A . n 
A 1 260 THR 260 260 260 THR THR A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 MET 263 263 263 MET MET A . n 
A 1 264 ILE 264 264 264 ILE ILE A . n 
A 1 265 GLU 265 265 265 GLU GLU A . n 
A 1 266 ARG 266 266 266 ARG ARG A . n 
A 1 267 GLN 267 267 267 GLN GLN A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 TYR 271 271 271 TYR TYR A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 ILE 274 274 274 ILE ILE A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 ALA 276 276 276 ALA ALA A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 LYS 279 279 279 LYS LYS A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 TYR 281 281 281 TYR TYR A . n 
A 1 282 ARG 282 282 282 ARG ARG A . n 
A 1 283 ASP 283 283 283 ASP ASP A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 SER 287 287 287 SER SER A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 THR 289 289 289 THR THR A . n 
A 1 290 PHE 290 290 290 PHE PHE A . n 
A 1 291 TRP 291 291 291 TRP TRP A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 ALA 294 294 294 ALA ALA A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 ASP 296 296 296 ASP ASP A . n 
A 1 297 HIS 297 297 297 HIS HIS A . n 
A 1 298 THR 298 298 298 THR THR A . n 
A 1 299 TRP 299 299 299 TRP TRP A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 ASP 301 301 301 ASP ASP A . n 
A 1 302 ASN 302 302 302 ASN ASN A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 VAL 305 305 305 VAL VAL A . n 
A 1 306 HIS 306 306 306 HIS HIS A . n 
A 1 307 GLY 307 307 307 GLY GLY A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 TRP 311 311 311 TRP TRP A . n 
A 1 312 PRO 312 312 312 PRO PRO A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 PHE 315 315 315 PHE PHE A . n 
A 1 316 ASP 316 316 316 ASP ASP A . n 
A 1 317 GLU 317 317 317 GLU GLU A . n 
A 1 318 GLN 318 318 318 GLN GLN A . n 
A 1 319 HIS 319 319 319 HIS HIS A . n 
A 1 320 LYS 320 320 320 LYS LYS A . n 
A 1 321 PRO 321 321 321 PRO PRO A . n 
A 1 322 LYS 322 322 322 LYS LYS A . n 
A 1 323 PRO 323 323 323 PRO PRO A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 PHE 325 325 325 PHE PHE A . n 
A 1 326 TRP 326 326 326 TRP TRP A . n 
A 1 327 ARG 327 327 327 ARG ARG A . n 
A 1 328 ALA 328 328 328 ALA ALA A . n 
A 1 329 VAL 329 329 329 VAL VAL A . n 
A 1 330 SER 330 330 330 SER SER A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ASN 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   4   SER SER B . n 
B 1 5   LEU 5   5   5   LEU LEU B . n 
B 1 6   PRO 6   6   6   PRO PRO B . n 
B 1 7   SER 7   7   7   SER SER B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   ARG 9   9   9   ARG ARG B . n 
B 1 10  ASP 10  10  10  ASP ASP B . n 
B 1 11  VAL 11  11  11  VAL VAL B . n 
B 1 12  PHE 12  12  12  PHE PHE B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  ASN 14  14  14  ASN ASN B . n 
B 1 15  ASP 15  15  15  ASP ASP B . n 
B 1 16  PHE 16  16  16  PHE PHE B . n 
B 1 17  ARG 17  17  17  ARG ARG B . n 
B 1 18  ILE 18  18  18  ILE ILE B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  VAL 22  22  22  VAL VAL B . n 
B 1 23  ASN 23  23  23  ASN ASN B . n 
B 1 24  PRO 24  24  24  PRO PRO B . n 
B 1 25  VAL 25  25  25  VAL VAL B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  ILE 27  27  27  ILE ILE B . n 
B 1 28  GLU 28  28  28  GLU GLU B . n 
B 1 29  MET 29  29  29  MET MET B . n 
B 1 30  GLN 30  30  30  GLN GLN B . n 
B 1 31  LYS 31  31  31  LYS LYS B . n 
B 1 32  GLN 32  32  32  GLN GLN B . n 
B 1 33  LEU 33  33  33  LEU LEU B . n 
B 1 34  LEU 34  34  34  LEU LEU B . n 
B 1 35  ILE 35  35  35  ILE ILE B . n 
B 1 36  ASP 36  36  36  ASP ASP B . n 
B 1 37  HIS 37  37  37  HIS HIS B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  ILE 41  41  41  ILE ILE B . n 
B 1 42  THR 42  42  42  THR THR B . n 
B 1 43  ALA 43  43  43  ALA ALA B . n 
B 1 44  GLU 44  44  44  GLU GLU B . n 
B 1 45  ASN 45  45  45  ASN ASN B . n 
B 1 46  HIS 46  46  46  HIS HIS B . n 
B 1 47  MET 47  47  47  MET MET B . n 
B 1 48  LYS 48  48  48  LYS LYS B . n 
B 1 49  PHE 49  49  49  PHE PHE B . n 
B 1 50  GLU 50  50  50  GLU GLU B . n 
B 1 51  HIS 51  51  51  HIS HIS B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  GLN 53  53  53  GLN GLN B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  GLU 56  56  56  GLU GLU B . n 
B 1 57  GLY 57  57  57  GLY GLY B . n 
B 1 58  LYS 58  58  58  LYS LYS B . n 
B 1 59  PHE 59  59  59  PHE PHE B . n 
B 1 60  THR 60  60  60  THR THR B . n 
B 1 61  PHE 61  61  61  PHE PHE B . n 
B 1 62  GLN 62  62  62  GLN GLN B . n 
B 1 63  GLU 63  63  63  GLU GLU B . n 
B 1 64  ALA 64  64  64  ALA ALA B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  ARG 66  66  66  ARG ARG B . n 
B 1 67  ILE 67  67  67  ILE ILE B . n 
B 1 68  VAL 68  68  68  VAL VAL B . n 
B 1 69  ASP 69  69  69  ASP ASP B . n 
B 1 70  PHE 70  70  70  PHE PHE B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  CYS 72  72  72  CYS CYS B . n 
B 1 73  SER 73  73  73  SER SER B . n 
B 1 74  HIS 74  74  74  HIS HIS B . n 
B 1 75  ARG 75  75  75  ARG ARG B . n 
B 1 76  MET 76  76  76  MET MET B . n 
B 1 77  ALA 77  77  77  ALA ALA B . n 
B 1 78  VAL 78  78  78  VAL VAL B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  GLY 80  80  80  GLY GLY B . n 
B 1 81  HIS 81  81  81  HIS HIS B . n 
B 1 82  THR 82  82  82  THR THR B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  TRP 85  85  85  TRP TRP B . n 
B 1 86  HIS 86  86  86  HIS HIS B . n 
B 1 87  ASN 87  87  87  ASN ASN B . n 
B 1 88  GLN 88  88  88  GLN GLN B . n 
B 1 89  THR 89  89  89  THR THR B . n 
B 1 90  PRO 90  90  90  PRO PRO B . n 
B 1 91  ASP 91  91  91  ASP ASP B . n 
B 1 92  TRP 92  92  92  TRP TRP B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  PHE 94  94  94  PHE PHE B . n 
B 1 95  GLN 95  95  95  GLN GLN B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  GLN 98  98  98  GLN GLN B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 HIS 100 100 100 HIS HIS B . n 
B 1 101 PHE 101 101 101 PHE PHE B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 SER 103 103 103 SER SER B . n 
B 1 104 ARG 104 104 104 ARG ARG B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 VAL 106 106 106 VAL VAL B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 LEU 108 108 108 LEU LEU B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 ARG 110 110 110 ARG ARG B . n 
B 1 111 MET 111 111 111 MET MET B . n 
B 1 112 LYS 112 112 112 LYS LYS B . n 
B 1 113 CYS 113 113 113 CYS CYS B . n 
B 1 114 HIS 114 114 114 HIS HIS B . n 
B 1 115 ILE 115 115 115 ILE ILE B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 THR 117 117 117 THR THR B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 VAL 119 119 119 VAL VAL B . n 
B 1 120 ARG 120 120 120 ARG ARG B . n 
B 1 121 ARG 121 121 121 ARG ARG B . n 
B 1 122 TYR 122 122 122 TYR TYR B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 LYS 125 125 125 LYS LYS B . n 
B 1 126 ILE 126 126 126 ILE ILE B . n 
B 1 127 TYR 127 127 127 TYR TYR B . n 
B 1 128 CYS 128 128 128 CYS CYS B . n 
B 1 129 TRP 129 129 129 TRP TRP B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 ILE 132 132 132 ILE ILE B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 GLU 134 134 134 GLU GLU B . n 
B 1 135 ALA 135 135 135 ALA ALA B . n 
B 1 136 VAL 136 136 136 VAL VAL B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 ASP 138 138 138 ASP ASP B . n 
B 1 139 GLU 139 139 139 GLU GLU B . n 
B 1 140 GLY 140 140 140 GLY GLY B . n 
B 1 141 ASN 141 141 141 ASN ASN B . n 
B 1 142 GLU 142 142 142 GLU GLU B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 ARG 145 145 145 ARG ARG B . n 
B 1 146 PRO 146 146 146 PRO PRO B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 LYS 148 148 148 LYS LYS B . n 
B 1 149 TRP 149 149 149 TRP TRP B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 GLN 151 151 151 GLN GLN B . n 
B 1 152 ILE 152 152 152 ILE ILE B . n 
B 1 153 ILE 153 153 153 ILE ILE B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 ASP 155 155 155 ASP ASP B . n 
B 1 156 ASP 156 156 156 ASP ASP B . n 
B 1 157 PHE 157 157 157 PHE PHE B . n 
B 1 158 MET 158 158 158 MET MET B . n 
B 1 159 GLU 159 159 159 GLU GLU B . n 
B 1 160 GLN 160 160 160 GLN GLN B . n 
B 1 161 ALA 161 161 161 ALA ALA B . n 
B 1 162 PHE 162 162 162 PHE PHE B . n 
B 1 163 LEU 163 163 163 LEU LEU B . n 
B 1 164 TYR 164 164 164 TYR TYR B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 TYR 166 166 166 TYR TYR B . n 
B 1 167 GLU 167 167 167 GLU GLU B . n 
B 1 168 ALA 168 168 168 ALA ALA B . n 
B 1 169 ASP 169 169 169 ASP ASP B . n 
B 1 170 PRO 170 170 170 PRO PRO B . n 
B 1 171 ASP 171 171 171 ASP ASP B . n 
B 1 172 ALA 172 172 172 ALA ALA B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 LEU 174 174 174 LEU LEU B . n 
B 1 175 PHE 175 175 175 PHE PHE B . n 
B 1 176 TYR 176 176 176 TYR TYR B . n 
B 1 177 ASN 177 177 177 ASN ASN B . n 
B 1 178 ASP 178 178 178 ASP ASP B . n 
B 1 179 TYR 179 179 179 TYR TYR B . n 
B 1 180 ASN 180 180 180 ASN ASN B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 CYS 182 182 182 CYS CYS B . n 
B 1 183 PHE 183 183 183 PHE PHE B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 GLU 185 185 185 GLU GLU B . n 
B 1 186 LYS 186 186 186 LYS LYS B . n 
B 1 187 ARG 187 187 187 ARG ARG B . n 
B 1 188 GLU 188 188 188 GLU GLU B . n 
B 1 189 LYS 189 189 189 LYS LYS B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 PHE 191 191 191 PHE PHE B . n 
B 1 192 ALA 192 192 192 ALA ALA B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 VAL 194 194 194 VAL VAL B . n 
B 1 195 LYS 195 195 195 LYS LYS B . n 
B 1 196 SER 196 196 196 SER SER B . n 
B 1 197 LEU 197 197 197 LEU LEU B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 ASP 199 199 199 ASP ASP B . n 
B 1 200 LYS 200 200 200 LYS LYS B . n 
B 1 201 GLY 201 201 201 GLY GLY B . n 
B 1 202 ILE 202 202 202 ILE ILE B . n 
B 1 203 PRO 203 203 203 PRO PRO B . n 
B 1 204 ILE 204 204 204 ILE ILE B . n 
B 1 205 HIS 205 205 205 HIS HIS B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 ILE 207 207 207 ILE ILE B . n 
B 1 208 GLY 208 208 208 GLY GLY B . n 
B 1 209 MET 209 209 209 MET MET B . n 
B 1 210 GLN 210 210 210 GLN GLN B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 HIS 212 212 212 HIS HIS B . n 
B 1 213 TRP 213 213 213 TRP TRP B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 LEU 215 215 215 LEU LEU B . n 
B 1 216 THR 216 216 216 THR THR B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 PRO 218 218 218 PRO PRO B . n 
B 1 219 SER 219 219 219 SER SER B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 GLU 222 222 222 GLU GLU B . n 
B 1 223 ILE 223 223 223 ILE ILE B . n 
B 1 224 ARG 224 224 224 ARG ARG B . n 
B 1 225 ALA 225 225 225 ALA ALA B . n 
B 1 226 ALA 226 226 226 ALA ALA B . n 
B 1 227 ILE 227 227 227 ILE ILE B . n 
B 1 228 GLU 228 228 228 GLU GLU B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 TYR 230 230 230 TYR TYR B . n 
B 1 231 ALA 231 231 231 ALA ALA B . n 
B 1 232 SER 232 232 232 SER SER B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 GLY 234 234 234 GLY GLY B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 LEU 237 237 237 LEU LEU B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 ILE 239 239 239 ILE ILE B . n 
B 1 240 THR 240 240 240 THR THR B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 ASP 243 243 243 ASP ASP B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 SER 245 245 245 SER SER B . n 
B 1 246 MET 246 246 246 MET MET B . n 
B 1 247 PHE 247 247 247 PHE PHE B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 PHE 249 249 249 PHE PHE B . n 
B 1 250 HIS 250 250 250 HIS HIS B . n 
B 1 251 ASP 251 251 251 ASP ASP B . n 
B 1 252 ARG 252 252 252 ARG ARG B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 THR 254 254 254 THR THR B . n 
B 1 255 ASP 255 255 255 ASP ASP B . n 
B 1 256 LEU 256 256 256 LEU LEU B . n 
B 1 257 ALA 257 257 257 ALA ALA B . n 
B 1 258 ALA 258 258 258 ALA ALA B . n 
B 1 259 PRO 259 259 259 PRO PRO B . n 
B 1 260 THR 260 260 260 THR THR B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 MET 263 263 263 MET MET B . n 
B 1 264 ILE 264 264 264 ILE ILE B . n 
B 1 265 GLU 265 265 265 GLU GLU B . n 
B 1 266 ARG 266 266 266 ARG ARG B . n 
B 1 267 GLN 267 267 267 GLN GLN B . n 
B 1 268 ALA 268 268 268 ALA ALA B . n 
B 1 269 GLU 269 269 269 GLU GLU B . n 
B 1 270 ARG 270 270 270 ARG ARG B . n 
B 1 271 TYR 271 271 271 TYR TYR B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 GLN 273 273 273 GLN GLN B . n 
B 1 274 ILE 274 274 274 ILE ILE B . n 
B 1 275 PHE 275 275 275 PHE PHE B . n 
B 1 276 ALA 276 276 276 ALA ALA B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 PHE 278 278 278 PHE PHE B . n 
B 1 279 LYS 279 279 279 LYS LYS B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 TYR 281 281 281 TYR TYR B . n 
B 1 282 ARG 282 282 282 ARG ARG B . n 
B 1 283 ASP 283 283 283 ASP ASP B . n 
B 1 284 VAL 284 284 284 VAL VAL B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 SER 287 287 287 SER SER B . n 
B 1 288 VAL 288 288 288 VAL VAL B . n 
B 1 289 THR 289 289 289 THR THR B . n 
B 1 290 PHE 290 290 290 PHE PHE B . n 
B 1 291 TRP 291 291 291 TRP TRP B . n 
B 1 292 GLY 292 292 292 GLY GLY B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 ALA 294 294 294 ALA ALA B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 ASP 296 296 296 ASP ASP B . n 
B 1 297 HIS 297 297 297 HIS HIS B . n 
B 1 298 THR 298 298 298 THR THR B . n 
B 1 299 TRP 299 299 299 TRP TRP B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 ASP 301 301 301 ASP ASP B . n 
B 1 302 ASN 302 302 302 ASN ASN B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 VAL 305 305 305 VAL VAL B . n 
B 1 306 HIS 306 306 306 HIS HIS B . n 
B 1 307 GLY 307 307 307 GLY GLY B . n 
B 1 308 ARG 308 308 308 ARG ARG B . n 
B 1 309 LYS 309 309 309 LYS LYS B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 TRP 311 311 311 TRP TRP B . n 
B 1 312 PRO 312 312 312 PRO PRO B . n 
B 1 313 LEU 313 313 313 LEU LEU B . n 
B 1 314 LEU 314 314 314 LEU LEU B . n 
B 1 315 PHE 315 315 315 PHE PHE B . n 
B 1 316 ASP 316 316 316 ASP ASP B . n 
B 1 317 GLU 317 317 317 GLU GLU B . n 
B 1 318 GLN 318 318 318 GLN GLN B . n 
B 1 319 HIS 319 319 319 HIS HIS B . n 
B 1 320 LYS 320 320 320 LYS LYS B . n 
B 1 321 PRO 321 321 321 PRO PRO B . n 
B 1 322 LYS 322 322 322 LYS LYS B . n 
B 1 323 PRO 323 323 323 PRO PRO B . n 
B 1 324 ALA 324 324 324 ALA ALA B . n 
B 1 325 PHE 325 325 325 PHE PHE B . n 
B 1 326 TRP 326 326 326 TRP TRP B . n 
B 1 327 ARG 327 327 327 ARG ARG B . n 
B 1 328 ALA 328 328 328 ALA ALA B . n 
B 1 329 VAL 329 329 329 VAL VAL B . n 
B 1 330 SER 330 330 330 SER SER B . n 
B 1 331 VAL 331 331 331 VAL VAL B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 A1ID6 1 C A1ID6 1 B XBA 401 n 
C 2 XYP   2 C XYP   2 B XBA 401 n 
D 3 A1ID6 1 D A1ID6 1 A XHF 401 n 
D 3 XYP   2 D XYP   2 A XHF 401 n 
D 3 XYP   3 D XYP   3 A XHF 401 n 
D 3 XYP   4 D XYP   4 A XHF 401 n 
D 3 XYP   5 D XYP   5 A XHF 401 n 
D 3 XYP   6 D XYP   6 A XHF 401 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 XYP   ? ? XYP   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 A1ID6 ? ? A1ID6 ? ? 'SUBJECT OF INVESTIGATION' ? 
3 XYP   ? ? XYP   ? ? 'SUBJECT OF INVESTIGATION' ? 
4 A1ID6 ? ? A1ID6 ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 4 HOH 1   401 144 HOH HOH A . 
E 4 HOH 2   402 325 HOH HOH A . 
E 4 HOH 3   403 6   HOH HOH A . 
E 4 HOH 4   404 133 HOH HOH A . 
E 4 HOH 5   405 231 HOH HOH A . 
E 4 HOH 6   406 413 HOH HOH A . 
E 4 HOH 7   407 353 HOH HOH A . 
E 4 HOH 8   408 273 HOH HOH A . 
E 4 HOH 9   409 1   HOH HOH A . 
E 4 HOH 10  410 251 HOH HOH A . 
E 4 HOH 11  411 435 HOH HOH A . 
E 4 HOH 12  412 202 HOH HOH A . 
E 4 HOH 13  413 282 HOH HOH A . 
E 4 HOH 14  414 112 HOH HOH A . 
E 4 HOH 15  415 36  HOH HOH A . 
E 4 HOH 16  416 182 HOH HOH A . 
E 4 HOH 17  417 108 HOH HOH A . 
E 4 HOH 18  418 139 HOH HOH A . 
E 4 HOH 19  419 162 HOH HOH A . 
E 4 HOH 20  420 141 HOH HOH A . 
E 4 HOH 21  421 431 HOH HOH A . 
E 4 HOH 22  422 125 HOH HOH A . 
E 4 HOH 23  423 12  HOH HOH A . 
E 4 HOH 24  424 299 HOH HOH A . 
E 4 HOH 25  425 140 HOH HOH A . 
E 4 HOH 26  426 185 HOH HOH A . 
E 4 HOH 27  427 132 HOH HOH A . 
E 4 HOH 28  428 303 HOH HOH A . 
E 4 HOH 29  429 58  HOH HOH A . 
E 4 HOH 30  430 8   HOH HOH A . 
E 4 HOH 31  431 59  HOH HOH A . 
E 4 HOH 32  432 107 HOH HOH A . 
E 4 HOH 33  433 17  HOH HOH A . 
E 4 HOH 34  434 239 HOH HOH A . 
E 4 HOH 35  435 193 HOH HOH A . 
E 4 HOH 36  436 404 HOH HOH A . 
E 4 HOH 37  437 194 HOH HOH A . 
E 4 HOH 38  438 153 HOH HOH A . 
E 4 HOH 39  439 73  HOH HOH A . 
E 4 HOH 40  440 15  HOH HOH A . 
E 4 HOH 41  441 113 HOH HOH A . 
E 4 HOH 42  442 41  HOH HOH A . 
E 4 HOH 43  443 7   HOH HOH A . 
E 4 HOH 44  444 64  HOH HOH A . 
E 4 HOH 45  445 152 HOH HOH A . 
E 4 HOH 46  446 138 HOH HOH A . 
E 4 HOH 47  447 49  HOH HOH A . 
E 4 HOH 48  448 137 HOH HOH A . 
E 4 HOH 49  449 45  HOH HOH A . 
E 4 HOH 50  450 455 HOH HOH A . 
E 4 HOH 51  451 62  HOH HOH A . 
E 4 HOH 52  452 66  HOH HOH A . 
E 4 HOH 53  453 28  HOH HOH A . 
E 4 HOH 54  454 163 HOH HOH A . 
E 4 HOH 55  455 346 HOH HOH A . 
E 4 HOH 56  456 179 HOH HOH A . 
E 4 HOH 57  457 16  HOH HOH A . 
E 4 HOH 58  458 78  HOH HOH A . 
E 4 HOH 59  459 19  HOH HOH A . 
E 4 HOH 60  460 55  HOH HOH A . 
E 4 HOH 61  461 32  HOH HOH A . 
E 4 HOH 62  462 48  HOH HOH A . 
E 4 HOH 63  463 433 HOH HOH A . 
E 4 HOH 64  464 89  HOH HOH A . 
E 4 HOH 65  465 5   HOH HOH A . 
E 4 HOH 66  466 186 HOH HOH A . 
E 4 HOH 67  467 240 HOH HOH A . 
E 4 HOH 68  468 85  HOH HOH A . 
E 4 HOH 69  469 329 HOH HOH A . 
E 4 HOH 70  470 114 HOH HOH A . 
E 4 HOH 71  471 255 HOH HOH A . 
E 4 HOH 72  472 389 HOH HOH A . 
E 4 HOH 73  473 468 HOH HOH A . 
E 4 HOH 74  474 106 HOH HOH A . 
E 4 HOH 75  475 18  HOH HOH A . 
E 4 HOH 76  476 101 HOH HOH A . 
E 4 HOH 77  477 157 HOH HOH A . 
E 4 HOH 78  478 92  HOH HOH A . 
E 4 HOH 79  479 168 HOH HOH A . 
E 4 HOH 80  480 317 HOH HOH A . 
E 4 HOH 81  481 11  HOH HOH A . 
E 4 HOH 82  482 33  HOH HOH A . 
E 4 HOH 83  483 23  HOH HOH A . 
E 4 HOH 84  484 241 HOH HOH A . 
E 4 HOH 85  485 250 HOH HOH A . 
E 4 HOH 86  486 272 HOH HOH A . 
E 4 HOH 87  487 53  HOH HOH A . 
E 4 HOH 88  488 242 HOH HOH A . 
E 4 HOH 89  489 188 HOH HOH A . 
E 4 HOH 90  490 74  HOH HOH A . 
E 4 HOH 91  491 184 HOH HOH A . 
E 4 HOH 92  492 215 HOH HOH A . 
E 4 HOH 93  493 81  HOH HOH A . 
E 4 HOH 94  494 396 HOH HOH A . 
E 4 HOH 95  495 180 HOH HOH A . 
E 4 HOH 96  496 279 HOH HOH A . 
E 4 HOH 97  497 340 HOH HOH A . 
E 4 HOH 98  498 150 HOH HOH A . 
E 4 HOH 99  499 261 HOH HOH A . 
E 4 HOH 100 500 363 HOH HOH A . 
E 4 HOH 101 501 44  HOH HOH A . 
E 4 HOH 102 502 327 HOH HOH A . 
E 4 HOH 103 503 198 HOH HOH A . 
E 4 HOH 104 504 263 HOH HOH A . 
E 4 HOH 105 505 336 HOH HOH A . 
E 4 HOH 106 506 86  HOH HOH A . 
E 4 HOH 107 507 452 HOH HOH A . 
E 4 HOH 108 508 124 HOH HOH A . 
E 4 HOH 109 509 247 HOH HOH A . 
E 4 HOH 110 510 51  HOH HOH A . 
E 4 HOH 111 511 91  HOH HOH A . 
E 4 HOH 112 512 374 HOH HOH A . 
E 4 HOH 113 513 306 HOH HOH A . 
E 4 HOH 114 514 412 HOH HOH A . 
E 4 HOH 115 515 79  HOH HOH A . 
E 4 HOH 116 516 286 HOH HOH A . 
E 4 HOH 117 517 121 HOH HOH A . 
E 4 HOH 118 518 314 HOH HOH A . 
E 4 HOH 119 519 27  HOH HOH A . 
E 4 HOH 120 520 398 HOH HOH A . 
E 4 HOH 121 521 80  HOH HOH A . 
E 4 HOH 122 522 256 HOH HOH A . 
E 4 HOH 123 523 218 HOH HOH A . 
E 4 HOH 124 524 426 HOH HOH A . 
E 4 HOH 125 525 37  HOH HOH A . 
E 4 HOH 126 526 88  HOH HOH A . 
E 4 HOH 127 527 75  HOH HOH A . 
E 4 HOH 128 528 149 HOH HOH A . 
E 4 HOH 129 529 366 HOH HOH A . 
E 4 HOH 130 530 83  HOH HOH A . 
E 4 HOH 131 531 201 HOH HOH A . 
E 4 HOH 132 532 228 HOH HOH A . 
E 4 HOH 133 533 482 HOH HOH A . 
E 4 HOH 134 534 128 HOH HOH A . 
E 4 HOH 135 535 259 HOH HOH A . 
E 4 HOH 136 536 117 HOH HOH A . 
E 4 HOH 137 537 312 HOH HOH A . 
E 4 HOH 138 538 320 HOH HOH A . 
E 4 HOH 139 539 24  HOH HOH A . 
E 4 HOH 140 540 267 HOH HOH A . 
E 4 HOH 141 541 146 HOH HOH A . 
E 4 HOH 142 542 308 HOH HOH A . 
E 4 HOH 143 543 100 HOH HOH A . 
E 4 HOH 144 544 480 HOH HOH A . 
E 4 HOH 145 545 20  HOH HOH A . 
E 4 HOH 146 546 164 HOH HOH A . 
E 4 HOH 147 547 406 HOH HOH A . 
E 4 HOH 148 548 338 HOH HOH A . 
E 4 HOH 149 549 322 HOH HOH A . 
E 4 HOH 150 550 422 HOH HOH A . 
E 4 HOH 151 551 63  HOH HOH A . 
E 4 HOH 152 552 197 HOH HOH A . 
E 4 HOH 153 553 400 HOH HOH A . 
E 4 HOH 154 554 284 HOH HOH A . 
E 4 HOH 155 555 187 HOH HOH A . 
E 4 HOH 156 556 226 HOH HOH A . 
E 4 HOH 157 557 236 HOH HOH A . 
E 4 HOH 158 558 345 HOH HOH A . 
E 4 HOH 159 559 266 HOH HOH A . 
E 4 HOH 160 560 99  HOH HOH A . 
E 4 HOH 161 561 294 HOH HOH A . 
E 4 HOH 162 562 447 HOH HOH A . 
E 4 HOH 163 563 111 HOH HOH A . 
E 4 HOH 164 564 232 HOH HOH A . 
E 4 HOH 165 565 379 HOH HOH A . 
E 4 HOH 166 566 190 HOH HOH A . 
E 4 HOH 167 567 84  HOH HOH A . 
E 4 HOH 168 568 501 HOH HOH A . 
E 4 HOH 169 569 136 HOH HOH A . 
E 4 HOH 170 570 441 HOH HOH A . 
E 4 HOH 171 571 211 HOH HOH A . 
E 4 HOH 172 572 472 HOH HOH A . 
E 4 HOH 173 573 31  HOH HOH A . 
E 4 HOH 174 574 210 HOH HOH A . 
E 4 HOH 175 575 475 HOH HOH A . 
E 4 HOH 176 576 196 HOH HOH A . 
E 4 HOH 177 577 457 HOH HOH A . 
E 4 HOH 178 578 373 HOH HOH A . 
E 4 HOH 179 579 478 HOH HOH A . 
E 4 HOH 180 580 257 HOH HOH A . 
E 4 HOH 181 581 453 HOH HOH A . 
E 4 HOH 182 582 415 HOH HOH A . 
E 4 HOH 183 583 291 HOH HOH A . 
E 4 HOH 184 584 328 HOH HOH A . 
E 4 HOH 185 585 280 HOH HOH A . 
E 4 HOH 186 586 471 HOH HOH A . 
E 4 HOH 187 587 381 HOH HOH A . 
E 4 HOH 188 588 395 HOH HOH A . 
E 4 HOH 189 589 470 HOH HOH A . 
E 4 HOH 190 590 234 HOH HOH A . 
E 4 HOH 191 591 383 HOH HOH A . 
E 4 HOH 192 592 467 HOH HOH A . 
E 4 HOH 193 593 458 HOH HOH A . 
E 4 HOH 194 594 361 HOH HOH A . 
E 4 HOH 195 595 297 HOH HOH A . 
E 4 HOH 196 596 408 HOH HOH A . 
E 4 HOH 197 597 344 HOH HOH A . 
E 4 HOH 198 598 481 HOH HOH A . 
E 4 HOH 199 599 474 HOH HOH A . 
E 4 HOH 200 600 473 HOH HOH A . 
E 4 HOH 201 601 143 HOH HOH A . 
E 4 HOH 202 602 484 HOH HOH A . 
E 4 HOH 203 603 476 HOH HOH A . 
E 4 HOH 204 604 368 HOH HOH A . 
E 4 HOH 205 605 335 HOH HOH A . 
E 4 HOH 206 606 318 HOH HOH A . 
E 4 HOH 207 607 477 HOH HOH A . 
E 4 HOH 208 608 479 HOH HOH A . 
E 4 HOH 209 609 142 HOH HOH A . 
E 4 HOH 210 610 393 HOH HOH A . 
E 4 HOH 211 611 456 HOH HOH A . 
E 4 HOH 212 612 288 HOH HOH A . 
E 4 HOH 213 613 450 HOH HOH A . 
E 4 HOH 214 614 401 HOH HOH A . 
E 4 HOH 215 615 183 HOH HOH A . 
E 4 HOH 216 616 271 HOH HOH A . 
E 4 HOH 217 617 350 HOH HOH A . 
E 4 HOH 218 618 446 HOH HOH A . 
E 4 HOH 219 619 367 HOH HOH A . 
E 4 HOH 220 620 448 HOH HOH A . 
E 4 HOH 221 621 378 HOH HOH A . 
E 4 HOH 222 622 258 HOH HOH A . 
E 4 HOH 223 623 483 HOH HOH A . 
E 4 HOH 224 624 466 HOH HOH A . 
E 4 HOH 225 625 486 HOH HOH A . 
E 4 HOH 226 626 131 HOH HOH A . 
E 4 HOH 227 627 391 HOH HOH A . 
E 4 HOH 228 628 262 HOH HOH A . 
E 4 HOH 229 629 440 HOH HOH A . 
E 4 HOH 230 630 171 HOH HOH A . 
E 4 HOH 231 631 451 HOH HOH A . 
E 4 HOH 232 632 437 HOH HOH A . 
E 4 HOH 233 633 351 HOH HOH A . 
E 4 HOH 234 634 388 HOH HOH A . 
E 4 HOH 235 635 123 HOH HOH A . 
E 4 HOH 236 636 238 HOH HOH A . 
E 4 HOH 237 637 469 HOH HOH A . 
E 4 HOH 238 638 283 HOH HOH A . 
E 4 HOH 239 639 324 HOH HOH A . 
E 4 HOH 240 640 387 HOH HOH A . 
E 4 HOH 241 641 356 HOH HOH A . 
E 4 HOH 242 642 333 HOH HOH A . 
E 4 HOH 243 643 275 HOH HOH A . 
E 4 HOH 244 644 375 HOH HOH A . 
E 4 HOH 245 645 208 HOH HOH A . 
E 4 HOH 246 646 343 HOH HOH A . 
E 4 HOH 247 647 362 HOH HOH A . 
E 4 HOH 248 648 292 HOH HOH A . 
E 4 HOH 249 649 365 HOH HOH A . 
E 4 HOH 250 650 167 HOH HOH A . 
E 4 HOH 251 651 429 HOH HOH A . 
E 4 HOH 252 652 384 HOH HOH A . 
E 4 HOH 253 653 402 HOH HOH A . 
E 4 HOH 254 654 302 HOH HOH A . 
F 4 HOH 1   401 25  HOH HOH B . 
F 4 HOH 2   402 264 HOH HOH B . 
F 4 HOH 3   403 13  HOH HOH B . 
F 4 HOH 4   404 321 HOH HOH B . 
F 4 HOH 5   405 265 HOH HOH B . 
F 4 HOH 6   406 160 HOH HOH B . 
F 4 HOH 7   407 3   HOH HOH B . 
F 4 HOH 8   408 427 HOH HOH B . 
F 4 HOH 9   409 224 HOH HOH B . 
F 4 HOH 10  410 229 HOH HOH B . 
F 4 HOH 11  411 243 HOH HOH B . 
F 4 HOH 12  412 192 HOH HOH B . 
F 4 HOH 13  413 223 HOH HOH B . 
F 4 HOH 14  414 289 HOH HOH B . 
F 4 HOH 15  415 326 HOH HOH B . 
F 4 HOH 16  416 225 HOH HOH B . 
F 4 HOH 17  417 296 HOH HOH B . 
F 4 HOH 18  418 214 HOH HOH B . 
F 4 HOH 19  419 70  HOH HOH B . 
F 4 HOH 20  420 90  HOH HOH B . 
F 4 HOH 21  421 126 HOH HOH B . 
F 4 HOH 22  422 9   HOH HOH B . 
F 4 HOH 23  423 130 HOH HOH B . 
F 4 HOH 24  424 237 HOH HOH B . 
F 4 HOH 25  425 72  HOH HOH B . 
F 4 HOH 26  426 290 HOH HOH B . 
F 4 HOH 27  427 46  HOH HOH B . 
F 4 HOH 28  428 2   HOH HOH B . 
F 4 HOH 29  429 334 HOH HOH B . 
F 4 HOH 30  430 38  HOH HOH B . 
F 4 HOH 31  431 460 HOH HOH B . 
F 4 HOH 32  432 293 HOH HOH B . 
F 4 HOH 33  433 270 HOH HOH B . 
F 4 HOH 34  434 134 HOH HOH B . 
F 4 HOH 35  435 4   HOH HOH B . 
F 4 HOH 36  436 249 HOH HOH B . 
F 4 HOH 37  437 47  HOH HOH B . 
F 4 HOH 38  438 104 HOH HOH B . 
F 4 HOH 39  439 170 HOH HOH B . 
F 4 HOH 40  440 14  HOH HOH B . 
F 4 HOH 41  441 176 HOH HOH B . 
F 4 HOH 42  442 54  HOH HOH B . 
F 4 HOH 43  443 97  HOH HOH B . 
F 4 HOH 44  444 359 HOH HOH B . 
F 4 HOH 45  445 189 HOH HOH B . 
F 4 HOH 46  446 60  HOH HOH B . 
F 4 HOH 47  447 67  HOH HOH B . 
F 4 HOH 48  448 252 HOH HOH B . 
F 4 HOH 49  449 115 HOH HOH B . 
F 4 HOH 50  450 109 HOH HOH B . 
F 4 HOH 51  451 120 HOH HOH B . 
F 4 HOH 52  452 94  HOH HOH B . 
F 4 HOH 53  453 307 HOH HOH B . 
F 4 HOH 54  454 61  HOH HOH B . 
F 4 HOH 55  455 219 HOH HOH B . 
F 4 HOH 56  456 195 HOH HOH B . 
F 4 HOH 57  457 173 HOH HOH B . 
F 4 HOH 58  458 217 HOH HOH B . 
F 4 HOH 59  459 40  HOH HOH B . 
F 4 HOH 60  460 43  HOH HOH B . 
F 4 HOH 61  461 127 HOH HOH B . 
F 4 HOH 62  462 30  HOH HOH B . 
F 4 HOH 63  463 76  HOH HOH B . 
F 4 HOH 64  464 357 HOH HOH B . 
F 4 HOH 65  465 21  HOH HOH B . 
F 4 HOH 66  466 397 HOH HOH B . 
F 4 HOH 67  467 65  HOH HOH B . 
F 4 HOH 68  468 260 HOH HOH B . 
F 4 HOH 69  469 110 HOH HOH B . 
F 4 HOH 70  470 116 HOH HOH B . 
F 4 HOH 71  471 268 HOH HOH B . 
F 4 HOH 72  472 98  HOH HOH B . 
F 4 HOH 73  473 56  HOH HOH B . 
F 4 HOH 74  474 77  HOH HOH B . 
F 4 HOH 75  475 233 HOH HOH B . 
F 4 HOH 76  476 57  HOH HOH B . 
F 4 HOH 77  477 10  HOH HOH B . 
F 4 HOH 78  478 221 HOH HOH B . 
F 4 HOH 79  479 22  HOH HOH B . 
F 4 HOH 80  480 29  HOH HOH B . 
F 4 HOH 81  481 159 HOH HOH B . 
F 4 HOH 82  482 207 HOH HOH B . 
F 4 HOH 83  483 248 HOH HOH B . 
F 4 HOH 84  484 39  HOH HOH B . 
F 4 HOH 85  485 147 HOH HOH B . 
F 4 HOH 86  486 175 HOH HOH B . 
F 4 HOH 87  487 200 HOH HOH B . 
F 4 HOH 88  488 209 HOH HOH B . 
F 4 HOH 89  489 382 HOH HOH B . 
F 4 HOH 90  490 35  HOH HOH B . 
F 4 HOH 91  491 372 HOH HOH B . 
F 4 HOH 92  492 310 HOH HOH B . 
F 4 HOH 93  493 380 HOH HOH B . 
F 4 HOH 94  494 339 HOH HOH B . 
F 4 HOH 95  495 177 HOH HOH B . 
F 4 HOH 96  496 161 HOH HOH B . 
F 4 HOH 97  497 204 HOH HOH B . 
F 4 HOH 98  498 199 HOH HOH B . 
F 4 HOH 99  499 154 HOH HOH B . 
F 4 HOH 100 500 191 HOH HOH B . 
F 4 HOH 101 501 148 HOH HOH B . 
F 4 HOH 102 502 151 HOH HOH B . 
F 4 HOH 103 503 105 HOH HOH B . 
F 4 HOH 104 504 119 HOH HOH B . 
F 4 HOH 105 505 178 HOH HOH B . 
F 4 HOH 106 506 244 HOH HOH B . 
F 4 HOH 107 507 87  HOH HOH B . 
F 4 HOH 108 508 212 HOH HOH B . 
F 4 HOH 109 509 216 HOH HOH B . 
F 4 HOH 110 510 82  HOH HOH B . 
F 4 HOH 111 511 102 HOH HOH B . 
F 4 HOH 112 512 158 HOH HOH B . 
F 4 HOH 113 513 403 HOH HOH B . 
F 4 HOH 114 514 205 HOH HOH B . 
F 4 HOH 115 515 103 HOH HOH B . 
F 4 HOH 116 516 122 HOH HOH B . 
F 4 HOH 117 517 394 HOH HOH B . 
F 4 HOH 118 518 96  HOH HOH B . 
F 4 HOH 119 519 315 HOH HOH B . 
F 4 HOH 120 520 319 HOH HOH B . 
F 4 HOH 121 521 26  HOH HOH B . 
F 4 HOH 122 522 420 HOH HOH B . 
F 4 HOH 123 523 434 HOH HOH B . 
F 4 HOH 124 524 118 HOH HOH B . 
F 4 HOH 125 525 169 HOH HOH B . 
F 4 HOH 126 526 93  HOH HOH B . 
F 4 HOH 127 527 42  HOH HOH B . 
F 4 HOH 128 528 399 HOH HOH B . 
F 4 HOH 129 529 454 HOH HOH B . 
F 4 HOH 130 530 445 HOH HOH B . 
F 4 HOH 131 531 490 HOH HOH B . 
F 4 HOH 132 532 135 HOH HOH B . 
F 4 HOH 133 533 409 HOH HOH B . 
F 4 HOH 134 534 376 HOH HOH B . 
F 4 HOH 135 535 95  HOH HOH B . 
F 4 HOH 136 536 50  HOH HOH B . 
F 4 HOH 137 537 254 HOH HOH B . 
F 4 HOH 138 538 276 HOH HOH B . 
F 4 HOH 139 539 245 HOH HOH B . 
F 4 HOH 140 540 129 HOH HOH B . 
F 4 HOH 141 541 71  HOH HOH B . 
F 4 HOH 142 542 496 HOH HOH B . 
F 4 HOH 143 543 348 HOH HOH B . 
F 4 HOH 144 544 246 HOH HOH B . 
F 4 HOH 145 545 230 HOH HOH B . 
F 4 HOH 146 546 438 HOH HOH B . 
F 4 HOH 147 547 461 HOH HOH B . 
F 4 HOH 148 548 311 HOH HOH B . 
F 4 HOH 149 549 165 HOH HOH B . 
F 4 HOH 150 550 497 HOH HOH B . 
F 4 HOH 151 551 52  HOH HOH B . 
F 4 HOH 152 552 174 HOH HOH B . 
F 4 HOH 153 553 443 HOH HOH B . 
F 4 HOH 154 554 385 HOH HOH B . 
F 4 HOH 155 555 492 HOH HOH B . 
F 4 HOH 156 556 436 HOH HOH B . 
F 4 HOH 157 557 274 HOH HOH B . 
F 4 HOH 158 558 313 HOH HOH B . 
F 4 HOH 159 559 405 HOH HOH B . 
F 4 HOH 160 560 360 HOH HOH B . 
F 4 HOH 161 561 222 HOH HOH B . 
F 4 HOH 162 562 181 HOH HOH B . 
F 4 HOH 163 563 414 HOH HOH B . 
F 4 HOH 164 564 68  HOH HOH B . 
F 4 HOH 165 565 34  HOH HOH B . 
F 4 HOH 166 566 424 HOH HOH B . 
F 4 HOH 167 567 439 HOH HOH B . 
F 4 HOH 168 568 305 HOH HOH B . 
F 4 HOH 169 569 220 HOH HOH B . 
F 4 HOH 170 570 487 HOH HOH B . 
F 4 HOH 171 571 155 HOH HOH B . 
F 4 HOH 172 572 354 HOH HOH B . 
F 4 HOH 173 573 156 HOH HOH B . 
F 4 HOH 174 574 419 HOH HOH B . 
F 4 HOH 175 575 69  HOH HOH B . 
F 4 HOH 176 576 417 HOH HOH B . 
F 4 HOH 177 577 166 HOH HOH B . 
F 4 HOH 178 578 227 HOH HOH B . 
F 4 HOH 179 579 449 HOH HOH B . 
F 4 HOH 180 580 145 HOH HOH B . 
F 4 HOH 181 581 442 HOH HOH B . 
F 4 HOH 182 582 491 HOH HOH B . 
F 4 HOH 183 583 358 HOH HOH B . 
F 4 HOH 184 584 330 HOH HOH B . 
F 4 HOH 185 585 494 HOH HOH B . 
F 4 HOH 186 586 386 HOH HOH B . 
F 4 HOH 187 587 298 HOH HOH B . 
F 4 HOH 188 588 323 HOH HOH B . 
F 4 HOH 189 589 499 HOH HOH B . 
F 4 HOH 190 590 489 HOH HOH B . 
F 4 HOH 191 591 332 HOH HOH B . 
F 4 HOH 192 592 430 HOH HOH B . 
F 4 HOH 193 593 172 HOH HOH B . 
F 4 HOH 194 594 498 HOH HOH B . 
F 4 HOH 195 595 418 HOH HOH B . 
F 4 HOH 196 596 309 HOH HOH B . 
F 4 HOH 197 597 392 HOH HOH B . 
F 4 HOH 198 598 341 HOH HOH B . 
F 4 HOH 199 599 278 HOH HOH B . 
F 4 HOH 200 600 500 HOH HOH B . 
F 4 HOH 201 601 316 HOH HOH B . 
F 4 HOH 202 602 269 HOH HOH B . 
F 4 HOH 203 603 493 HOH HOH B . 
F 4 HOH 204 604 301 HOH HOH B . 
F 4 HOH 205 605 465 HOH HOH B . 
F 4 HOH 206 606 352 HOH HOH B . 
F 4 HOH 207 607 377 HOH HOH B . 
F 4 HOH 208 608 349 HOH HOH B . 
F 4 HOH 209 609 425 HOH HOH B . 
F 4 HOH 210 610 364 HOH HOH B . 
F 4 HOH 211 611 428 HOH HOH B . 
F 4 HOH 212 612 206 HOH HOH B . 
F 4 HOH 213 613 444 HOH HOH B . 
F 4 HOH 214 614 416 HOH HOH B . 
F 4 HOH 215 615 369 HOH HOH B . 
F 4 HOH 216 616 285 HOH HOH B . 
F 4 HOH 217 617 423 HOH HOH B . 
F 4 HOH 218 618 371 HOH HOH B . 
F 4 HOH 219 619 300 HOH HOH B . 
F 4 HOH 220 620 355 HOH HOH B . 
F 4 HOH 221 621 342 HOH HOH B . 
F 4 HOH 222 622 253 HOH HOH B . 
F 4 HOH 223 623 459 HOH HOH B . 
F 4 HOH 224 624 410 HOH HOH B . 
F 4 HOH 225 625 432 HOH HOH B . 
F 4 HOH 226 626 485 HOH HOH B . 
F 4 HOH 227 627 203 HOH HOH B . 
F 4 HOH 228 628 390 HOH HOH B . 
F 4 HOH 229 629 370 HOH HOH B . 
F 4 HOH 230 630 337 HOH HOH B . 
F 4 HOH 231 631 235 HOH HOH B . 
F 4 HOH 232 632 411 HOH HOH B . 
F 4 HOH 233 633 277 HOH HOH B . 
F 4 HOH 234 634 462 HOH HOH B . 
F 4 HOH 235 635 495 HOH HOH B . 
F 4 HOH 236 636 281 HOH HOH B . 
F 4 HOH 237 637 421 HOH HOH B . 
F 4 HOH 238 638 331 HOH HOH B . 
F 4 HOH 239 639 407 HOH HOH B . 
F 4 HOH 240 640 463 HOH HOH B . 
F 4 HOH 241 641 213 HOH HOH B . 
F 4 HOH 242 642 304 HOH HOH B . 
F 4 HOH 243 643 347 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.17.1_3660 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.17.1_3660 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   91.993 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9FKL 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     169.014 
_cell.length_a_esd                 ? 
_cell.length_b                     80.526 
_cell.length_b_esd                 ? 
_cell.length_c                     79.074 
_cell.length_c_esd                 ? 
_cell.volume                       1075547.941 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9FKL 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            'C 2y' 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9FKL 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.48 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          64.66 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2M Sodium acetate and 0.1M Sodium cacodylate buffer at pH 6.5.' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 200K' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-12-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.54 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'ROTATING ANODE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        RIGAKU 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.54 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_synchrotron_site       ? 
# 
_reflns.B_iso_Wilson_estimate                          23.76 
_reflns.entry_id                                       9FKL 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.40 
_reflns.d_resolution_low                               40.26 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     41609 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.1 
_reflns.pdbx_Rpim_I_all                                0.05 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.40 
_reflns_shell.d_res_low                                     2.48 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4308 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.61 
_reflns_shell.pdbx_Rpim_I_all                               0.31 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.79 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.52 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.63 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9FKL 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.40 
_refine.ls_d_res_low                             40.26 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     41599 
_refine.ls_number_reflns_R_free                  2129 
_refine.ls_number_reflns_R_work                  39470 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.96 
_refine.ls_percent_reflns_R_free                 5.12 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1558 
_refine.ls_R_factor_R_free                       0.2057 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1532 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.0917 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2543 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.40 
_refine_hist.d_res_low                        40.26 
_refine_hist.number_atoms_solvent             497 
_refine_hist.number_atoms_total               5983 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5412 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         74 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0071 ? 5694 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9073 ? 7736 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0563 ? 823  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0056 ? 998  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 7.7647 ? 795  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.40 2.46  . . 150 2605 99.96  . . . . 0.2046 . . . . . . . . . . . 0.2889 
'X-RAY DIFFRACTION' 2.46 2.52  . . 143 2593 100.00 . . . . 0.2010 . . . . . . . . . . . 0.3005 
'X-RAY DIFFRACTION' 2.52 2.59  . . 130 2631 99.96  . . . . 0.1937 . . . . . . . . . . . 0.2575 
'X-RAY DIFFRACTION' 2.59 2.66  . . 139 2588 100.00 . . . . 0.1965 . . . . . . . . . . . 0.2769 
'X-RAY DIFFRACTION' 2.66 2.75  . . 167 2620 99.96  . . . . 0.1856 . . . . . . . . . . . 0.2728 
'X-RAY DIFFRACTION' 2.75 2.85  . . 142 2599 99.96  . . . . 0.1787 . . . . . . . . . . . 0.2443 
'X-RAY DIFFRACTION' 2.85 2.96  . . 149 2624 100.00 . . . . 0.1808 . . . . . . . . . . . 0.2594 
'X-RAY DIFFRACTION' 2.96 3.09  . . 139 2629 99.96  . . . . 0.1749 . . . . . . . . . . . 0.2559 
'X-RAY DIFFRACTION' 3.09 3.26  . . 134 2640 100.00 . . . . 0.1653 . . . . . . . . . . . 0.2145 
'X-RAY DIFFRACTION' 3.26 3.46  . . 120 2655 100.00 . . . . 0.1500 . . . . . . . . . . . 0.1896 
'X-RAY DIFFRACTION' 3.46 3.73  . . 148 2618 100.00 . . . . 0.1302 . . . . . . . . . . . 0.1618 
'X-RAY DIFFRACTION' 3.73 4.10  . . 136 2642 100.00 . . . . 0.1171 . . . . . . . . . . . 0.1608 
'X-RAY DIFFRACTION' 4.10 4.70  . . 159 2640 100.00 . . . . 0.1119 . . . . . . . . . . . 0.1482 
'X-RAY DIFFRACTION' 4.70 5.91  . . 151 2653 100.00 . . . . 0.1328 . . . . . . . . . . . 0.1693 
'X-RAY DIFFRACTION' 5.92 40.26 . . 122 2733 99.69  . . . . 0.1496 . . . . . . . . . . . 0.1930 
# 
_struct.entry_id                     9FKL 
_struct.title                        
;The structure of glycosynthase IXT6 (E241G mutant), the intracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylohexaose-F molecules
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9FKL 
_struct_keywords.text            'IXT6, glycosynthase, hydrolase, Geobacillus proteiniphilus T-6, Geobacillus stearothermophilus' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q09LY9_GEOSE 
_struct_ref.pdbx_db_accession          Q09LY9 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MNSSLPSLRDVFANDFRIGAAVNPVTIEMQKQLLIDHVNSITAENHMKFEHLQPEEGKFTFQEADRIVDFACSHRMAVRG
HTLVWHNQTPDWVFQDGQGHFVSRDVLLERMKCHISTVVRRYKGKIYCWDVINEAVADEGNELLRPSKWRQIIGDDFMEQ
AFLYAYEADPDALLFYNDYNECFPEKREKIFALVKSLRDKGIPIHGIGMQAHWSLTRPSLDEIRAAIERYASLGVVLHIT
ELDVSMFEFHDRRTDLAAPTSEMIERQAERYGQIFALFKEYRDVIQSVTFWGIADDHTWLDNFPVHGRKNWPLLFDEQHK
PKPAFWRAVSV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9FKL A 1 ? 331 ? Q09LY9 1 ? 331 ? 1 331 
2 1 9FKL B 1 ? 331 ? Q09LY9 1 ? 331 ? 1 331 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9FKL GLY A 241 ? UNP Q09LY9 GLU 241 'engineered mutation' 241 1 
2 9FKL GLY B 241 ? UNP Q09LY9 GLU 241 'engineered mutation' 241 2 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E 
2 1 B,C,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 7   ? PHE A 12  ? SER A 7   PHE A 12  1 ? 6  
HELX_P HELX_P2  AA2 ASN A 23  ? GLN A 30  ? ASN A 23  GLN A 30  1 ? 8  
HELX_P HELX_P3  AA3 GLN A 30  ? VAL A 38  ? GLN A 30  VAL A 38  1 ? 9  
HELX_P HELX_P4  AA4 LYS A 48  ? GLN A 53  ? LYS A 48  GLN A 53  1 ? 6  
HELX_P HELX_P5  AA5 PHE A 61  ? HIS A 74  ? PHE A 61  HIS A 74  1 ? 14 
HELX_P HELX_P6  AA6 PRO A 90  ? GLN A 95  ? PRO A 90  GLN A 95  5 ? 6  
HELX_P HELX_P7  AA7 SER A 103 ? LYS A 123 ? SER A 103 LYS A 123 1 ? 21 
HELX_P HELX_P8  AA8 SER A 147 ? GLY A 154 ? SER A 147 GLY A 154 1 ? 8  
HELX_P HELX_P9  AA9 ASP A 156 ? ASP A 169 ? ASP A 156 ASP A 169 1 ? 14 
HELX_P HELX_P10 AB1 PHE A 183 ? LYS A 200 ? PHE A 183 LYS A 200 1 ? 18 
HELX_P HELX_P11 AB2 SER A 219 ? SER A 232 ? SER A 219 SER A 232 1 ? 14 
HELX_P HELX_P12 AB3 THR A 260 ? TYR A 281 ? THR A 260 TYR A 281 1 ? 22 
HELX_P HELX_P13 AB4 THR A 298 ? ASN A 302 ? THR A 298 ASN A 302 5 ? 5  
HELX_P HELX_P14 AB5 LYS A 322 ? VAL A 329 ? LYS A 322 VAL A 329 1 ? 8  
HELX_P HELX_P15 AB6 SER B 7   ? PHE B 12  ? SER B 7   PHE B 12  1 ? 6  
HELX_P HELX_P16 AB7 ASN B 23  ? GLN B 30  ? ASN B 23  GLN B 30  1 ? 8  
HELX_P HELX_P17 AB8 GLN B 30  ? VAL B 38  ? GLN B 30  VAL B 38  1 ? 9  
HELX_P HELX_P18 AB9 LYS B 48  ? GLN B 53  ? LYS B 48  GLN B 53  1 ? 6  
HELX_P HELX_P19 AC1 PHE B 61  ? SER B 73  ? PHE B 61  SER B 73  1 ? 13 
HELX_P HELX_P20 AC2 PRO B 90  ? GLN B 95  ? PRO B 90  GLN B 95  5 ? 6  
HELX_P HELX_P21 AC3 SER B 103 ? LYS B 123 ? SER B 103 LYS B 123 1 ? 21 
HELX_P HELX_P22 AC4 SER B 147 ? GLY B 154 ? SER B 147 GLY B 154 1 ? 8  
HELX_P HELX_P23 AC5 ASP B 156 ? ASP B 169 ? ASP B 156 ASP B 169 1 ? 14 
HELX_P HELX_P24 AC6 PHE B 183 ? LYS B 200 ? PHE B 183 LYS B 200 1 ? 18 
HELX_P HELX_P25 AC7 SER B 219 ? SER B 232 ? SER B 219 SER B 232 1 ? 14 
HELX_P HELX_P26 AC8 THR B 260 ? TYR B 281 ? THR B 260 TYR B 281 1 ? 22 
HELX_P HELX_P27 AC9 THR B 298 ? ASN B 302 ? THR B 298 ASN B 302 5 ? 5  
HELX_P HELX_P28 AD1 LYS B 322 ? SER B 330 ? LYS B 322 SER B 330 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale one  ? C A1ID6 . O4 ? ? ? 1_555 C XYP . C1 ? ? C A1ID6 1 C XYP 2 1_555 ? ? ? ? ? ? ? 1.427 ? ? 
covale2 covale one  ? D A1ID6 . O4 ? ? ? 1_555 D XYP . C1 ? ? D A1ID6 1 D XYP 2 1_555 ? ? ? ? ? ? ? 1.443 ? ? 
covale3 covale both ? D XYP   . O4 ? ? ? 1_555 D XYP . C1 ? ? D XYP   2 D XYP 3 1_555 ? ? ? ? ? ? ? 1.427 ? ? 
covale4 covale both ? D XYP   . O4 ? ? ? 1_555 D XYP . C1 ? ? D XYP   3 D XYP 4 1_555 ? ? ? ? ? ? ? 1.453 ? ? 
covale5 covale both ? D XYP   . O4 ? ? ? 1_555 D XYP . C1 ? ? D XYP   4 D XYP 5 1_555 ? ? ? ? ? ? ? 1.423 ? ? 
covale6 covale both ? D XYP   . O4 ? ? ? 1_555 D XYP . C1 ? ? D XYP   5 D XYP 6 1_555 ? ? ? ? ? ? ? 1.407 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 HIS 81  A . ? HIS 81  A THR 82  A ? THR 82  A 1 -0.25 
2 ARG 217 A . ? ARG 217 A PRO 218 A ? PRO 218 A 1 -7.73 
3 PHE 303 A . ? PHE 303 A PRO 304 A ? PRO 304 A 1 -1.42 
4 HIS 81  B . ? HIS 81  B THR 82  B ? THR 82  B 1 0.76  
5 ARG 217 B . ? ARG 217 B PRO 218 B ? PRO 218 B 1 -1.99 
6 PHE 303 B . ? PHE 303 B PRO 304 B ? PRO 304 B 1 -1.49 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 10 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel 
AA1 2 3  ? parallel 
AA1 3 4  ? parallel 
AA1 4 5  ? parallel 
AA1 5 6  ? parallel 
AA1 6 7  ? parallel 
AA1 7 8  ? parallel 
AA1 8 9  ? parallel 
AA1 9 10 ? parallel 
AA2 1 2  ? parallel 
AA2 2 3  ? parallel 
AA2 3 4  ? parallel 
AA2 4 5  ? parallel 
AA2 5 6  ? parallel 
AA2 6 7  ? parallel 
AA2 7 8  ? parallel 
AA2 8 9  ? parallel 
AA2 9 10 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  HIS A 212 ? SER A 214 ? HIS A 212 SER A 214 
AA1 2  VAL A 236 ? SER A 245 ? VAL A 236 SER A 245 
AA1 3  ILE A 285 ? PHE A 290 ? ILE A 285 PHE A 290 
AA1 4  ARG A 17  ? VAL A 22  ? ARG A 17  VAL A 22  
AA1 5  SER A 40  ? ALA A 43  ? SER A 40  ALA A 43  
AA1 6  ALA A 77  ? TRP A 85  ? ALA A 77  TRP A 85  
AA1 7  CYS A 128 ? ASN A 133 ? CYS A 128 ASN A 133 
AA1 8  LEU A 173 ? ASP A 178 ? LEU A 173 ASP A 178 
AA1 9  GLY A 206 ? MET A 209 ? GLY A 206 MET A 209 
AA1 10 VAL A 236 ? SER A 245 ? VAL A 236 SER A 245 
AA2 1  HIS B 212 ? SER B 214 ? HIS B 212 SER B 214 
AA2 2  VAL B 236 ? SER B 245 ? VAL B 236 SER B 245 
AA2 3  ILE B 285 ? PHE B 290 ? ILE B 285 PHE B 290 
AA2 4  ARG B 17  ? VAL B 22  ? ARG B 17  VAL B 22  
AA2 5  SER B 40  ? ALA B 43  ? SER B 40  ALA B 43  
AA2 6  ALA B 77  ? TRP B 85  ? ALA B 77  TRP B 85  
AA2 7  CYS B 128 ? ASN B 133 ? CYS B 128 ASN B 133 
AA2 8  LEU B 173 ? ASP B 178 ? LEU B 173 ASP B 178 
AA2 9  GLY B 206 ? MET B 209 ? GLY B 206 MET B 209 
AA2 10 VAL B 236 ? SER B 245 ? VAL B 236 SER B 245 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  N TRP A 213 ? N TRP A 213 O SER A 245 ? O SER A 245 
AA1 2 3  N ILE A 239 ? N ILE A 239 O THR A 289 ? O THR A 289 
AA1 3 4  O VAL A 288 ? O VAL A 288 N ARG A 17  ? N ARG A 17  
AA1 4 5  N VAL A 22  ? N VAL A 22  O THR A 42  ? O THR A 42  
AA1 5 6  N ILE A 41  ? N ILE A 41  O ARG A 79  ? O ARG A 79  
AA1 6 7  N GLY A 80  ? N GLY A 80  O CYS A 128 ? O CYS A 128 
AA1 7 8  N TRP A 129 ? N TRP A 129 O PHE A 175 ? O PHE A 175 
AA1 8 9  N TYR A 176 ? N TYR A 176 O GLY A 208 ? O GLY A 208 
AA1 9 10 N MET A 209 ? N MET A 209 O HIS A 238 ? O HIS A 238 
AA2 1 2  N TRP B 213 ? N TRP B 213 O SER B 245 ? O SER B 245 
AA2 2 3  N ILE B 239 ? N ILE B 239 O THR B 289 ? O THR B 289 
AA2 3 4  O VAL B 288 ? O VAL B 288 N ARG B 17  ? N ARG B 17  
AA2 4 5  N VAL B 22  ? N VAL B 22  O THR B 42  ? O THR B 42  
AA2 5 6  N ILE B 41  ? N ILE B 41  O ARG B 79  ? O ARG B 79  
AA2 6 7  N GLY B 80  ? N GLY B 80  O CYS B 128 ? O CYS B 128 
AA2 7 8  N TRP B 129 ? N TRP B 129 O PHE B 175 ? O PHE B 175 
AA2 8 9  N TYR B 176 ? N TYR B 176 O GLY B 208 ? O GLY B 208 
AA2 9 10 N MET B 209 ? N MET B 209 O HIS B 238 ? O HIS B 238 
# 
_pdbx_entry_details.entry_id                   9FKL 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NH1 A ARG 17  ? ? O A HOH 401 ? ? 2.05 
2 1 O   A HOH 560 ? ? O A HOH 594 ? ? 2.14 
3 1 NE  B ARG 252 ? ? O B HOH 401 ? ? 2.15 
4 1 OG  A SER 103 ? ? O A HOH 402 ? ? 2.17 
5 1 OE2 B GLU 142 ? ? O B HOH 402 ? ? 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 96  ? ? -104.97 -168.21 
2 1 ILE A 293 ? ? -146.15 -31.93  
3 1 ARG A 308 ? ? -109.48 -164.27 
4 1 ASN B 45  ? ? -140.24 -22.26  
5 1 ARG B 75  ? ? 31.39   56.74   
6 1 ILE B 293 ? ? -144.44 -30.24  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 -x,y,-z         
3 x+1/2,y+1/2,z   
4 -x+1/2,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 1 ? A MET 1 
2 1 Y 1 A ASN 2 ? A ASN 2 
3 1 Y 1 B MET 1 ? B MET 1 
4 1 Y 1 B ASN 2 ? B ASN 2 
5 1 Y 1 B SER 3 ? B SER 3 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1ID6 C1   C N R 1   
A1ID6 C2   C N R 2   
A1ID6 C3   C N S 3   
A1ID6 C4   C N R 4   
A1ID6 C5   C N N 5   
A1ID6 O2   O N N 6   
A1ID6 O3   O N N 7   
A1ID6 O4   O N N 8   
A1ID6 O5   O N N 9   
A1ID6 F1   F N N 10  
A1ID6 H1   H N N 11  
A1ID6 H2   H N N 12  
A1ID6 H3   H N N 13  
A1ID6 H4   H N N 14  
A1ID6 H51  H N N 15  
A1ID6 H52  H N N 16  
A1ID6 HO2  H N N 17  
A1ID6 HO3  H N N 18  
A1ID6 HO4  H N N 19  
ALA   N    N N N 20  
ALA   CA   C N S 21  
ALA   C    C N N 22  
ALA   O    O N N 23  
ALA   CB   C N N 24  
ALA   OXT  O N N 25  
ALA   H    H N N 26  
ALA   H2   H N N 27  
ALA   HA   H N N 28  
ALA   HB1  H N N 29  
ALA   HB2  H N N 30  
ALA   HB3  H N N 31  
ALA   HXT  H N N 32  
ARG   N    N N N 33  
ARG   CA   C N S 34  
ARG   C    C N N 35  
ARG   O    O N N 36  
ARG   CB   C N N 37  
ARG   CG   C N N 38  
ARG   CD   C N N 39  
ARG   NE   N N N 40  
ARG   CZ   C N N 41  
ARG   NH1  N N N 42  
ARG   NH2  N N N 43  
ARG   OXT  O N N 44  
ARG   H    H N N 45  
ARG   H2   H N N 46  
ARG   HA   H N N 47  
ARG   HB2  H N N 48  
ARG   HB3  H N N 49  
ARG   HG2  H N N 50  
ARG   HG3  H N N 51  
ARG   HD2  H N N 52  
ARG   HD3  H N N 53  
ARG   HE   H N N 54  
ARG   HH11 H N N 55  
ARG   HH12 H N N 56  
ARG   HH21 H N N 57  
ARG   HH22 H N N 58  
ARG   HXT  H N N 59  
ASN   N    N N N 60  
ASN   CA   C N S 61  
ASN   C    C N N 62  
ASN   O    O N N 63  
ASN   CB   C N N 64  
ASN   CG   C N N 65  
ASN   OD1  O N N 66  
ASN   ND2  N N N 67  
ASN   OXT  O N N 68  
ASN   H    H N N 69  
ASN   H2   H N N 70  
ASN   HA   H N N 71  
ASN   HB2  H N N 72  
ASN   HB3  H N N 73  
ASN   HD21 H N N 74  
ASN   HD22 H N N 75  
ASN   HXT  H N N 76  
ASP   N    N N N 77  
ASP   CA   C N S 78  
ASP   C    C N N 79  
ASP   O    O N N 80  
ASP   CB   C N N 81  
ASP   CG   C N N 82  
ASP   OD1  O N N 83  
ASP   OD2  O N N 84  
ASP   OXT  O N N 85  
ASP   H    H N N 86  
ASP   H2   H N N 87  
ASP   HA   H N N 88  
ASP   HB2  H N N 89  
ASP   HB3  H N N 90  
ASP   HD2  H N N 91  
ASP   HXT  H N N 92  
CYS   N    N N N 93  
CYS   CA   C N R 94  
CYS   C    C N N 95  
CYS   O    O N N 96  
CYS   CB   C N N 97  
CYS   SG   S N N 98  
CYS   OXT  O N N 99  
CYS   H    H N N 100 
CYS   H2   H N N 101 
CYS   HA   H N N 102 
CYS   HB2  H N N 103 
CYS   HB3  H N N 104 
CYS   HG   H N N 105 
CYS   HXT  H N N 106 
GLN   N    N N N 107 
GLN   CA   C N S 108 
GLN   C    C N N 109 
GLN   O    O N N 110 
GLN   CB   C N N 111 
GLN   CG   C N N 112 
GLN   CD   C N N 113 
GLN   OE1  O N N 114 
GLN   NE2  N N N 115 
GLN   OXT  O N N 116 
GLN   H    H N N 117 
GLN   H2   H N N 118 
GLN   HA   H N N 119 
GLN   HB2  H N N 120 
GLN   HB3  H N N 121 
GLN   HG2  H N N 122 
GLN   HG3  H N N 123 
GLN   HE21 H N N 124 
GLN   HE22 H N N 125 
GLN   HXT  H N N 126 
GLU   N    N N N 127 
GLU   CA   C N S 128 
GLU   C    C N N 129 
GLU   O    O N N 130 
GLU   CB   C N N 131 
GLU   CG   C N N 132 
GLU   CD   C N N 133 
GLU   OE1  O N N 134 
GLU   OE2  O N N 135 
GLU   OXT  O N N 136 
GLU   H    H N N 137 
GLU   H2   H N N 138 
GLU   HA   H N N 139 
GLU   HB2  H N N 140 
GLU   HB3  H N N 141 
GLU   HG2  H N N 142 
GLU   HG3  H N N 143 
GLU   HE2  H N N 144 
GLU   HXT  H N N 145 
GLY   N    N N N 146 
GLY   CA   C N N 147 
GLY   C    C N N 148 
GLY   O    O N N 149 
GLY   OXT  O N N 150 
GLY   H    H N N 151 
GLY   H2   H N N 152 
GLY   HA2  H N N 153 
GLY   HA3  H N N 154 
GLY   HXT  H N N 155 
HIS   N    N N N 156 
HIS   CA   C N S 157 
HIS   C    C N N 158 
HIS   O    O N N 159 
HIS   CB   C N N 160 
HIS   CG   C Y N 161 
HIS   ND1  N Y N 162 
HIS   CD2  C Y N 163 
HIS   CE1  C Y N 164 
HIS   NE2  N Y N 165 
HIS   OXT  O N N 166 
HIS   H    H N N 167 
HIS   H2   H N N 168 
HIS   HA   H N N 169 
HIS   HB2  H N N 170 
HIS   HB3  H N N 171 
HIS   HD1  H N N 172 
HIS   HD2  H N N 173 
HIS   HE1  H N N 174 
HIS   HE2  H N N 175 
HIS   HXT  H N N 176 
HOH   O    O N N 177 
HOH   H1   H N N 178 
HOH   H2   H N N 179 
ILE   N    N N N 180 
ILE   CA   C N S 181 
ILE   C    C N N 182 
ILE   O    O N N 183 
ILE   CB   C N S 184 
ILE   CG1  C N N 185 
ILE   CG2  C N N 186 
ILE   CD1  C N N 187 
ILE   OXT  O N N 188 
ILE   H    H N N 189 
ILE   H2   H N N 190 
ILE   HA   H N N 191 
ILE   HB   H N N 192 
ILE   HG12 H N N 193 
ILE   HG13 H N N 194 
ILE   HG21 H N N 195 
ILE   HG22 H N N 196 
ILE   HG23 H N N 197 
ILE   HD11 H N N 198 
ILE   HD12 H N N 199 
ILE   HD13 H N N 200 
ILE   HXT  H N N 201 
LEU   N    N N N 202 
LEU   CA   C N S 203 
LEU   C    C N N 204 
LEU   O    O N N 205 
LEU   CB   C N N 206 
LEU   CG   C N N 207 
LEU   CD1  C N N 208 
LEU   CD2  C N N 209 
LEU   OXT  O N N 210 
LEU   H    H N N 211 
LEU   H2   H N N 212 
LEU   HA   H N N 213 
LEU   HB2  H N N 214 
LEU   HB3  H N N 215 
LEU   HG   H N N 216 
LEU   HD11 H N N 217 
LEU   HD12 H N N 218 
LEU   HD13 H N N 219 
LEU   HD21 H N N 220 
LEU   HD22 H N N 221 
LEU   HD23 H N N 222 
LEU   HXT  H N N 223 
LYS   N    N N N 224 
LYS   CA   C N S 225 
LYS   C    C N N 226 
LYS   O    O N N 227 
LYS   CB   C N N 228 
LYS   CG   C N N 229 
LYS   CD   C N N 230 
LYS   CE   C N N 231 
LYS   NZ   N N N 232 
LYS   OXT  O N N 233 
LYS   H    H N N 234 
LYS   H2   H N N 235 
LYS   HA   H N N 236 
LYS   HB2  H N N 237 
LYS   HB3  H N N 238 
LYS   HG2  H N N 239 
LYS   HG3  H N N 240 
LYS   HD2  H N N 241 
LYS   HD3  H N N 242 
LYS   HE2  H N N 243 
LYS   HE3  H N N 244 
LYS   HZ1  H N N 245 
LYS   HZ2  H N N 246 
LYS   HZ3  H N N 247 
LYS   HXT  H N N 248 
MET   N    N N N 249 
MET   CA   C N S 250 
MET   C    C N N 251 
MET   O    O N N 252 
MET   CB   C N N 253 
MET   CG   C N N 254 
MET   SD   S N N 255 
MET   CE   C N N 256 
MET   OXT  O N N 257 
MET   H    H N N 258 
MET   H2   H N N 259 
MET   HA   H N N 260 
MET   HB2  H N N 261 
MET   HB3  H N N 262 
MET   HG2  H N N 263 
MET   HG3  H N N 264 
MET   HE1  H N N 265 
MET   HE2  H N N 266 
MET   HE3  H N N 267 
MET   HXT  H N N 268 
PHE   N    N N N 269 
PHE   CA   C N S 270 
PHE   C    C N N 271 
PHE   O    O N N 272 
PHE   CB   C N N 273 
PHE   CG   C Y N 274 
PHE   CD1  C Y N 275 
PHE   CD2  C Y N 276 
PHE   CE1  C Y N 277 
PHE   CE2  C Y N 278 
PHE   CZ   C Y N 279 
PHE   OXT  O N N 280 
PHE   H    H N N 281 
PHE   H2   H N N 282 
PHE   HA   H N N 283 
PHE   HB2  H N N 284 
PHE   HB3  H N N 285 
PHE   HD1  H N N 286 
PHE   HD2  H N N 287 
PHE   HE1  H N N 288 
PHE   HE2  H N N 289 
PHE   HZ   H N N 290 
PHE   HXT  H N N 291 
PRO   N    N N N 292 
PRO   CA   C N S 293 
PRO   C    C N N 294 
PRO   O    O N N 295 
PRO   CB   C N N 296 
PRO   CG   C N N 297 
PRO   CD   C N N 298 
PRO   OXT  O N N 299 
PRO   H    H N N 300 
PRO   HA   H N N 301 
PRO   HB2  H N N 302 
PRO   HB3  H N N 303 
PRO   HG2  H N N 304 
PRO   HG3  H N N 305 
PRO   HD2  H N N 306 
PRO   HD3  H N N 307 
PRO   HXT  H N N 308 
SER   N    N N N 309 
SER   CA   C N S 310 
SER   C    C N N 311 
SER   O    O N N 312 
SER   CB   C N N 313 
SER   OG   O N N 314 
SER   OXT  O N N 315 
SER   H    H N N 316 
SER   H2   H N N 317 
SER   HA   H N N 318 
SER   HB2  H N N 319 
SER   HB3  H N N 320 
SER   HG   H N N 321 
SER   HXT  H N N 322 
THR   N    N N N 323 
THR   CA   C N S 324 
THR   C    C N N 325 
THR   O    O N N 326 
THR   CB   C N R 327 
THR   OG1  O N N 328 
THR   CG2  C N N 329 
THR   OXT  O N N 330 
THR   H    H N N 331 
THR   H2   H N N 332 
THR   HA   H N N 333 
THR   HB   H N N 334 
THR   HG1  H N N 335 
THR   HG21 H N N 336 
THR   HG22 H N N 337 
THR   HG23 H N N 338 
THR   HXT  H N N 339 
TRP   N    N N N 340 
TRP   CA   C N S 341 
TRP   C    C N N 342 
TRP   O    O N N 343 
TRP   CB   C N N 344 
TRP   CG   C Y N 345 
TRP   CD1  C Y N 346 
TRP   CD2  C Y N 347 
TRP   NE1  N Y N 348 
TRP   CE2  C Y N 349 
TRP   CE3  C Y N 350 
TRP   CZ2  C Y N 351 
TRP   CZ3  C Y N 352 
TRP   CH2  C Y N 353 
TRP   OXT  O N N 354 
TRP   H    H N N 355 
TRP   H2   H N N 356 
TRP   HA   H N N 357 
TRP   HB2  H N N 358 
TRP   HB3  H N N 359 
TRP   HD1  H N N 360 
TRP   HE1  H N N 361 
TRP   HE3  H N N 362 
TRP   HZ2  H N N 363 
TRP   HZ3  H N N 364 
TRP   HH2  H N N 365 
TRP   HXT  H N N 366 
TYR   N    N N N 367 
TYR   CA   C N S 368 
TYR   C    C N N 369 
TYR   O    O N N 370 
TYR   CB   C N N 371 
TYR   CG   C Y N 372 
TYR   CD1  C Y N 373 
TYR   CD2  C Y N 374 
TYR   CE1  C Y N 375 
TYR   CE2  C Y N 376 
TYR   CZ   C Y N 377 
TYR   OH   O N N 378 
TYR   OXT  O N N 379 
TYR   H    H N N 380 
TYR   H2   H N N 381 
TYR   HA   H N N 382 
TYR   HB2  H N N 383 
TYR   HB3  H N N 384 
TYR   HD1  H N N 385 
TYR   HD2  H N N 386 
TYR   HE1  H N N 387 
TYR   HE2  H N N 388 
TYR   HH   H N N 389 
TYR   HXT  H N N 390 
VAL   N    N N N 391 
VAL   CA   C N S 392 
VAL   C    C N N 393 
VAL   O    O N N 394 
VAL   CB   C N N 395 
VAL   CG1  C N N 396 
VAL   CG2  C N N 397 
VAL   OXT  O N N 398 
VAL   H    H N N 399 
VAL   H2   H N N 400 
VAL   HA   H N N 401 
VAL   HB   H N N 402 
VAL   HG11 H N N 403 
VAL   HG12 H N N 404 
VAL   HG13 H N N 405 
VAL   HG21 H N N 406 
VAL   HG22 H N N 407 
VAL   HG23 H N N 408 
VAL   HXT  H N N 409 
XYP   O1   O N N 410 
XYP   C1   C N R 411 
XYP   C2   C N R 412 
XYP   C3   C N S 413 
XYP   C4   C N R 414 
XYP   C5   C N N 415 
XYP   O2   O N N 416 
XYP   O3   O N N 417 
XYP   O4   O N N 418 
XYP   O5   O N N 419 
XYP   HO1  H N N 420 
XYP   H1   H N N 421 
XYP   H2   H N N 422 
XYP   H3   H N N 423 
XYP   H4   H N N 424 
XYP   H51  H N N 425 
XYP   H52  H N N 426 
XYP   HO2  H N N 427 
XYP   HO3  H N N 428 
XYP   HO4  H N N 429 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1ID6 F1  C1   sing N N 1   
A1ID6 O4  C4   sing N N 2   
A1ID6 C5  C4   sing N N 3   
A1ID6 C5  O5   sing N N 4   
A1ID6 C4  C3   sing N N 5   
A1ID6 C3  O3   sing N N 6   
A1ID6 C3  C2   sing N N 7   
A1ID6 O5  C1   sing N N 8   
A1ID6 C1  C2   sing N N 9   
A1ID6 C2  O2   sing N N 10  
A1ID6 C1  H1   sing N N 11  
A1ID6 C2  H2   sing N N 12  
A1ID6 C3  H3   sing N N 13  
A1ID6 C4  H4   sing N N 14  
A1ID6 C5  H51  sing N N 15  
A1ID6 C5  H52  sing N N 16  
A1ID6 O2  HO2  sing N N 17  
A1ID6 O3  HO3  sing N N 18  
A1ID6 O4  HO4  sing N N 19  
ALA   N   CA   sing N N 20  
ALA   N   H    sing N N 21  
ALA   N   H2   sing N N 22  
ALA   CA  C    sing N N 23  
ALA   CA  CB   sing N N 24  
ALA   CA  HA   sing N N 25  
ALA   C   O    doub N N 26  
ALA   C   OXT  sing N N 27  
ALA   CB  HB1  sing N N 28  
ALA   CB  HB2  sing N N 29  
ALA   CB  HB3  sing N N 30  
ALA   OXT HXT  sing N N 31  
ARG   N   CA   sing N N 32  
ARG   N   H    sing N N 33  
ARG   N   H2   sing N N 34  
ARG   CA  C    sing N N 35  
ARG   CA  CB   sing N N 36  
ARG   CA  HA   sing N N 37  
ARG   C   O    doub N N 38  
ARG   C   OXT  sing N N 39  
ARG   CB  CG   sing N N 40  
ARG   CB  HB2  sing N N 41  
ARG   CB  HB3  sing N N 42  
ARG   CG  CD   sing N N 43  
ARG   CG  HG2  sing N N 44  
ARG   CG  HG3  sing N N 45  
ARG   CD  NE   sing N N 46  
ARG   CD  HD2  sing N N 47  
ARG   CD  HD3  sing N N 48  
ARG   NE  CZ   sing N N 49  
ARG   NE  HE   sing N N 50  
ARG   CZ  NH1  sing N N 51  
ARG   CZ  NH2  doub N N 52  
ARG   NH1 HH11 sing N N 53  
ARG   NH1 HH12 sing N N 54  
ARG   NH2 HH21 sing N N 55  
ARG   NH2 HH22 sing N N 56  
ARG   OXT HXT  sing N N 57  
ASN   N   CA   sing N N 58  
ASN   N   H    sing N N 59  
ASN   N   H2   sing N N 60  
ASN   CA  C    sing N N 61  
ASN   CA  CB   sing N N 62  
ASN   CA  HA   sing N N 63  
ASN   C   O    doub N N 64  
ASN   C   OXT  sing N N 65  
ASN   CB  CG   sing N N 66  
ASN   CB  HB2  sing N N 67  
ASN   CB  HB3  sing N N 68  
ASN   CG  OD1  doub N N 69  
ASN   CG  ND2  sing N N 70  
ASN   ND2 HD21 sing N N 71  
ASN   ND2 HD22 sing N N 72  
ASN   OXT HXT  sing N N 73  
ASP   N   CA   sing N N 74  
ASP   N   H    sing N N 75  
ASP   N   H2   sing N N 76  
ASP   CA  C    sing N N 77  
ASP   CA  CB   sing N N 78  
ASP   CA  HA   sing N N 79  
ASP   C   O    doub N N 80  
ASP   C   OXT  sing N N 81  
ASP   CB  CG   sing N N 82  
ASP   CB  HB2  sing N N 83  
ASP   CB  HB3  sing N N 84  
ASP   CG  OD1  doub N N 85  
ASP   CG  OD2  sing N N 86  
ASP   OD2 HD2  sing N N 87  
ASP   OXT HXT  sing N N 88  
CYS   N   CA   sing N N 89  
CYS   N   H    sing N N 90  
CYS   N   H2   sing N N 91  
CYS   CA  C    sing N N 92  
CYS   CA  CB   sing N N 93  
CYS   CA  HA   sing N N 94  
CYS   C   O    doub N N 95  
CYS   C   OXT  sing N N 96  
CYS   CB  SG   sing N N 97  
CYS   CB  HB2  sing N N 98  
CYS   CB  HB3  sing N N 99  
CYS   SG  HG   sing N N 100 
CYS   OXT HXT  sing N N 101 
GLN   N   CA   sing N N 102 
GLN   N   H    sing N N 103 
GLN   N   H2   sing N N 104 
GLN   CA  C    sing N N 105 
GLN   CA  CB   sing N N 106 
GLN   CA  HA   sing N N 107 
GLN   C   O    doub N N 108 
GLN   C   OXT  sing N N 109 
GLN   CB  CG   sing N N 110 
GLN   CB  HB2  sing N N 111 
GLN   CB  HB3  sing N N 112 
GLN   CG  CD   sing N N 113 
GLN   CG  HG2  sing N N 114 
GLN   CG  HG3  sing N N 115 
GLN   CD  OE1  doub N N 116 
GLN   CD  NE2  sing N N 117 
GLN   NE2 HE21 sing N N 118 
GLN   NE2 HE22 sing N N 119 
GLN   OXT HXT  sing N N 120 
GLU   N   CA   sing N N 121 
GLU   N   H    sing N N 122 
GLU   N   H2   sing N N 123 
GLU   CA  C    sing N N 124 
GLU   CA  CB   sing N N 125 
GLU   CA  HA   sing N N 126 
GLU   C   O    doub N N 127 
GLU   C   OXT  sing N N 128 
GLU   CB  CG   sing N N 129 
GLU   CB  HB2  sing N N 130 
GLU   CB  HB3  sing N N 131 
GLU   CG  CD   sing N N 132 
GLU   CG  HG2  sing N N 133 
GLU   CG  HG3  sing N N 134 
GLU   CD  OE1  doub N N 135 
GLU   CD  OE2  sing N N 136 
GLU   OE2 HE2  sing N N 137 
GLU   OXT HXT  sing N N 138 
GLY   N   CA   sing N N 139 
GLY   N   H    sing N N 140 
GLY   N   H2   sing N N 141 
GLY   CA  C    sing N N 142 
GLY   CA  HA2  sing N N 143 
GLY   CA  HA3  sing N N 144 
GLY   C   O    doub N N 145 
GLY   C   OXT  sing N N 146 
GLY   OXT HXT  sing N N 147 
HIS   N   CA   sing N N 148 
HIS   N   H    sing N N 149 
HIS   N   H2   sing N N 150 
HIS   CA  C    sing N N 151 
HIS   CA  CB   sing N N 152 
HIS   CA  HA   sing N N 153 
HIS   C   O    doub N N 154 
HIS   C   OXT  sing N N 155 
HIS   CB  CG   sing N N 156 
HIS   CB  HB2  sing N N 157 
HIS   CB  HB3  sing N N 158 
HIS   CG  ND1  sing Y N 159 
HIS   CG  CD2  doub Y N 160 
HIS   ND1 CE1  doub Y N 161 
HIS   ND1 HD1  sing N N 162 
HIS   CD2 NE2  sing Y N 163 
HIS   CD2 HD2  sing N N 164 
HIS   CE1 NE2  sing Y N 165 
HIS   CE1 HE1  sing N N 166 
HIS   NE2 HE2  sing N N 167 
HIS   OXT HXT  sing N N 168 
HOH   O   H1   sing N N 169 
HOH   O   H2   sing N N 170 
ILE   N   CA   sing N N 171 
ILE   N   H    sing N N 172 
ILE   N   H2   sing N N 173 
ILE   CA  C    sing N N 174 
ILE   CA  CB   sing N N 175 
ILE   CA  HA   sing N N 176 
ILE   C   O    doub N N 177 
ILE   C   OXT  sing N N 178 
ILE   CB  CG1  sing N N 179 
ILE   CB  CG2  sing N N 180 
ILE   CB  HB   sing N N 181 
ILE   CG1 CD1  sing N N 182 
ILE   CG1 HG12 sing N N 183 
ILE   CG1 HG13 sing N N 184 
ILE   CG2 HG21 sing N N 185 
ILE   CG2 HG22 sing N N 186 
ILE   CG2 HG23 sing N N 187 
ILE   CD1 HD11 sing N N 188 
ILE   CD1 HD12 sing N N 189 
ILE   CD1 HD13 sing N N 190 
ILE   OXT HXT  sing N N 191 
LEU   N   CA   sing N N 192 
LEU   N   H    sing N N 193 
LEU   N   H2   sing N N 194 
LEU   CA  C    sing N N 195 
LEU   CA  CB   sing N N 196 
LEU   CA  HA   sing N N 197 
LEU   C   O    doub N N 198 
LEU   C   OXT  sing N N 199 
LEU   CB  CG   sing N N 200 
LEU   CB  HB2  sing N N 201 
LEU   CB  HB3  sing N N 202 
LEU   CG  CD1  sing N N 203 
LEU   CG  CD2  sing N N 204 
LEU   CG  HG   sing N N 205 
LEU   CD1 HD11 sing N N 206 
LEU   CD1 HD12 sing N N 207 
LEU   CD1 HD13 sing N N 208 
LEU   CD2 HD21 sing N N 209 
LEU   CD2 HD22 sing N N 210 
LEU   CD2 HD23 sing N N 211 
LEU   OXT HXT  sing N N 212 
LYS   N   CA   sing N N 213 
LYS   N   H    sing N N 214 
LYS   N   H2   sing N N 215 
LYS   CA  C    sing N N 216 
LYS   CA  CB   sing N N 217 
LYS   CA  HA   sing N N 218 
LYS   C   O    doub N N 219 
LYS   C   OXT  sing N N 220 
LYS   CB  CG   sing N N 221 
LYS   CB  HB2  sing N N 222 
LYS   CB  HB3  sing N N 223 
LYS   CG  CD   sing N N 224 
LYS   CG  HG2  sing N N 225 
LYS   CG  HG3  sing N N 226 
LYS   CD  CE   sing N N 227 
LYS   CD  HD2  sing N N 228 
LYS   CD  HD3  sing N N 229 
LYS   CE  NZ   sing N N 230 
LYS   CE  HE2  sing N N 231 
LYS   CE  HE3  sing N N 232 
LYS   NZ  HZ1  sing N N 233 
LYS   NZ  HZ2  sing N N 234 
LYS   NZ  HZ3  sing N N 235 
LYS   OXT HXT  sing N N 236 
MET   N   CA   sing N N 237 
MET   N   H    sing N N 238 
MET   N   H2   sing N N 239 
MET   CA  C    sing N N 240 
MET   CA  CB   sing N N 241 
MET   CA  HA   sing N N 242 
MET   C   O    doub N N 243 
MET   C   OXT  sing N N 244 
MET   CB  CG   sing N N 245 
MET   CB  HB2  sing N N 246 
MET   CB  HB3  sing N N 247 
MET   CG  SD   sing N N 248 
MET   CG  HG2  sing N N 249 
MET   CG  HG3  sing N N 250 
MET   SD  CE   sing N N 251 
MET   CE  HE1  sing N N 252 
MET   CE  HE2  sing N N 253 
MET   CE  HE3  sing N N 254 
MET   OXT HXT  sing N N 255 
PHE   N   CA   sing N N 256 
PHE   N   H    sing N N 257 
PHE   N   H2   sing N N 258 
PHE   CA  C    sing N N 259 
PHE   CA  CB   sing N N 260 
PHE   CA  HA   sing N N 261 
PHE   C   O    doub N N 262 
PHE   C   OXT  sing N N 263 
PHE   CB  CG   sing N N 264 
PHE   CB  HB2  sing N N 265 
PHE   CB  HB3  sing N N 266 
PHE   CG  CD1  doub Y N 267 
PHE   CG  CD2  sing Y N 268 
PHE   CD1 CE1  sing Y N 269 
PHE   CD1 HD1  sing N N 270 
PHE   CD2 CE2  doub Y N 271 
PHE   CD2 HD2  sing N N 272 
PHE   CE1 CZ   doub Y N 273 
PHE   CE1 HE1  sing N N 274 
PHE   CE2 CZ   sing Y N 275 
PHE   CE2 HE2  sing N N 276 
PHE   CZ  HZ   sing N N 277 
PHE   OXT HXT  sing N N 278 
PRO   N   CA   sing N N 279 
PRO   N   CD   sing N N 280 
PRO   N   H    sing N N 281 
PRO   CA  C    sing N N 282 
PRO   CA  CB   sing N N 283 
PRO   CA  HA   sing N N 284 
PRO   C   O    doub N N 285 
PRO   C   OXT  sing N N 286 
PRO   CB  CG   sing N N 287 
PRO   CB  HB2  sing N N 288 
PRO   CB  HB3  sing N N 289 
PRO   CG  CD   sing N N 290 
PRO   CG  HG2  sing N N 291 
PRO   CG  HG3  sing N N 292 
PRO   CD  HD2  sing N N 293 
PRO   CD  HD3  sing N N 294 
PRO   OXT HXT  sing N N 295 
SER   N   CA   sing N N 296 
SER   N   H    sing N N 297 
SER   N   H2   sing N N 298 
SER   CA  C    sing N N 299 
SER   CA  CB   sing N N 300 
SER   CA  HA   sing N N 301 
SER   C   O    doub N N 302 
SER   C   OXT  sing N N 303 
SER   CB  OG   sing N N 304 
SER   CB  HB2  sing N N 305 
SER   CB  HB3  sing N N 306 
SER   OG  HG   sing N N 307 
SER   OXT HXT  sing N N 308 
THR   N   CA   sing N N 309 
THR   N   H    sing N N 310 
THR   N   H2   sing N N 311 
THR   CA  C    sing N N 312 
THR   CA  CB   sing N N 313 
THR   CA  HA   sing N N 314 
THR   C   O    doub N N 315 
THR   C   OXT  sing N N 316 
THR   CB  OG1  sing N N 317 
THR   CB  CG2  sing N N 318 
THR   CB  HB   sing N N 319 
THR   OG1 HG1  sing N N 320 
THR   CG2 HG21 sing N N 321 
THR   CG2 HG22 sing N N 322 
THR   CG2 HG23 sing N N 323 
THR   OXT HXT  sing N N 324 
TRP   N   CA   sing N N 325 
TRP   N   H    sing N N 326 
TRP   N   H2   sing N N 327 
TRP   CA  C    sing N N 328 
TRP   CA  CB   sing N N 329 
TRP   CA  HA   sing N N 330 
TRP   C   O    doub N N 331 
TRP   C   OXT  sing N N 332 
TRP   CB  CG   sing N N 333 
TRP   CB  HB2  sing N N 334 
TRP   CB  HB3  sing N N 335 
TRP   CG  CD1  doub Y N 336 
TRP   CG  CD2  sing Y N 337 
TRP   CD1 NE1  sing Y N 338 
TRP   CD1 HD1  sing N N 339 
TRP   CD2 CE2  doub Y N 340 
TRP   CD2 CE3  sing Y N 341 
TRP   NE1 CE2  sing Y N 342 
TRP   NE1 HE1  sing N N 343 
TRP   CE2 CZ2  sing Y N 344 
TRP   CE3 CZ3  doub Y N 345 
TRP   CE3 HE3  sing N N 346 
TRP   CZ2 CH2  doub Y N 347 
TRP   CZ2 HZ2  sing N N 348 
TRP   CZ3 CH2  sing Y N 349 
TRP   CZ3 HZ3  sing N N 350 
TRP   CH2 HH2  sing N N 351 
TRP   OXT HXT  sing N N 352 
TYR   N   CA   sing N N 353 
TYR   N   H    sing N N 354 
TYR   N   H2   sing N N 355 
TYR   CA  C    sing N N 356 
TYR   CA  CB   sing N N 357 
TYR   CA  HA   sing N N 358 
TYR   C   O    doub N N 359 
TYR   C   OXT  sing N N 360 
TYR   CB  CG   sing N N 361 
TYR   CB  HB2  sing N N 362 
TYR   CB  HB3  sing N N 363 
TYR   CG  CD1  doub Y N 364 
TYR   CG  CD2  sing Y N 365 
TYR   CD1 CE1  sing Y N 366 
TYR   CD1 HD1  sing N N 367 
TYR   CD2 CE2  doub Y N 368 
TYR   CD2 HD2  sing N N 369 
TYR   CE1 CZ   doub Y N 370 
TYR   CE1 HE1  sing N N 371 
TYR   CE2 CZ   sing Y N 372 
TYR   CE2 HE2  sing N N 373 
TYR   CZ  OH   sing N N 374 
TYR   OH  HH   sing N N 375 
TYR   OXT HXT  sing N N 376 
VAL   N   CA   sing N N 377 
VAL   N   H    sing N N 378 
VAL   N   H2   sing N N 379 
VAL   CA  C    sing N N 380 
VAL   CA  CB   sing N N 381 
VAL   CA  HA   sing N N 382 
VAL   C   O    doub N N 383 
VAL   C   OXT  sing N N 384 
VAL   CB  CG1  sing N N 385 
VAL   CB  CG2  sing N N 386 
VAL   CB  HB   sing N N 387 
VAL   CG1 HG11 sing N N 388 
VAL   CG1 HG12 sing N N 389 
VAL   CG1 HG13 sing N N 390 
VAL   CG2 HG21 sing N N 391 
VAL   CG2 HG22 sing N N 392 
VAL   CG2 HG23 sing N N 393 
VAL   OXT HXT  sing N N 394 
XYP   O1  C1   sing N N 395 
XYP   O1  HO1  sing N N 396 
XYP   C1  C2   sing N N 397 
XYP   C1  O5   sing N N 398 
XYP   C1  H1   sing N N 399 
XYP   C2  C3   sing N N 400 
XYP   C2  O2   sing N N 401 
XYP   C2  H2   sing N N 402 
XYP   C3  C4   sing N N 403 
XYP   C3  O3   sing N N 404 
XYP   C3  H3   sing N N 405 
XYP   C4  C5   sing N N 406 
XYP   C4  O4   sing N N 407 
XYP   C4  H4   sing N N 408 
XYP   C5  O5   sing N N 409 
XYP   C5  H51  sing N N 410 
XYP   C5  H52  sing N N 411 
XYP   O2  HO2  sing N N 412 
XYP   O3  HO3  sing N N 413 
XYP   O4  HO4  sing N N 414 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 A1ID6 1 n 
2 XYP   2 n 
3 A1ID6 1 n 
3 XYP   2 n 
3 XYP   3 n 
3 XYP   4 n 
3 XYP   5 n 
3 XYP   6 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   9FKH 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 1 2 1' 
_space_group.name_Hall        'C 2y' 
_space_group.IT_number        5 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9FKL 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.005917 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000206 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012418 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012654 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735 ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER   A 1 3   ? -56.96408  -22.01725 -89.90625  1.000 39.59191  ? 3   SER   A N   1 
ATOM   2    C CA  . SER   A 1 3   ? -57.73704  -23.21211 -89.55073  1.000 55.33789  ? 3   SER   A CA  1 
ATOM   3    C C   . SER   A 1 3   ? -59.02111  -23.31705 -90.38071  1.000 51.95526  ? 3   SER   A C   1 
ATOM   4    O O   . SER   A 1 3   ? -59.28575  -24.35412 -91.00133  1.000 55.03368  ? 3   SER   A O   1 
ATOM   5    C CB  . SER   A 1 3   ? -58.07417  -23.21738 -88.05868  1.000 63.50896  ? 3   SER   A CB  1 
ATOM   6    O OG  . SER   A 1 3   ? -59.12005  -24.13071 -87.77492  1.000 79.04194  ? 3   SER   A OG  1 
ATOM   7    N N   . SER   A 1 4   ? -59.82599  -22.24896 -90.39080  1.000 45.09498  ? 4   SER   A N   1 
ATOM   8    C CA  . SER   A 1 4   ? -60.85319  -22.13786 -91.42526  1.000 49.63033  ? 4   SER   A CA  1 
ATOM   9    C C   . SER   A 1 4   ? -60.27385  -21.66873 -92.76107  1.000 35.34663  ? 4   SER   A C   1 
ATOM   10   O O   . SER   A 1 4   ? -61.02217  -21.54646 -93.73767  1.000 37.26123  ? 4   SER   A O   1 
ATOM   11   C CB  . SER   A 1 4   ? -61.98156  -21.19436 -90.97061  1.000 31.45884  ? 4   SER   A CB  1 
ATOM   12   O OG  . SER   A 1 4   ? -61.57358  -19.84440 -91.07739  1.000 51.48095  ? 4   SER   A OG  1 
ATOM   13   N N   . LEU   A 1 5   ? -58.96337  -21.41851 -92.82406  1.000 30.36972  ? 5   LEU   A N   1 
ATOM   14   C CA  . LEU   A 1 5   ? -58.30277  -20.89809 -94.01956  1.000 28.12718  ? 5   LEU   A CA  1 
ATOM   15   C C   . LEU   A 1 5   ? -58.12199  -22.00202 -95.05639  1.000 26.20289  ? 5   LEU   A C   1 
ATOM   16   O O   . LEU   A 1 5   ? -57.64845  -23.08691 -94.71673  1.000 28.66256  ? 5   LEU   A O   1 
ATOM   17   C CB  . LEU   A 1 5   ? -56.94643  -20.32433 -93.64841  1.000 23.61789  ? 5   LEU   A CB  1 
ATOM   18   C CG  . LEU   A 1 5   ? -56.51638  -19.01888 -94.29131  1.000 30.32148  ? 5   LEU   A CG  1 
ATOM   19   C CD1 . LEU   A 1 5   ? -57.50455  -17.91602 -93.97090  1.000 22.96721  ? 5   LEU   A CD1 1 
ATOM   20   C CD2 . LEU   A 1 5   ? -55.11835  -18.65200 -93.79491  1.000 32.36369  ? 5   LEU   A CD2 1 
ATOM   21   N N   . PRO   A 1 6   ? -58.45469  -21.75981 -96.32354  1.000 25.51682  ? 6   PRO   A N   1 
ATOM   22   C CA  . PRO   A 1 6   ? -58.13171  -22.74690 -97.36345  1.000 28.86458  ? 6   PRO   A CA  1 
ATOM   23   C C   . PRO   A 1 6   ? -56.62434  -22.94911 -97.51274  1.000 23.87958  ? 6   PRO   A C   1 
ATOM   24   O O   . PRO   A 1 6   ? -55.81517  -22.03903 -97.31216  1.000 17.67924  ? 6   PRO   A O   1 
ATOM   25   C CB  . PRO   A 1 6   ? -58.74493  -22.14425 -98.63689  1.000 24.61173  ? 6   PRO   A CB  1 
ATOM   26   C CG  . PRO   A 1 6   ? -59.75936  -21.14475 -98.14406  1.000 26.05097  ? 6   PRO   A CG  1 
ATOM   27   C CD  . PRO   A 1 6   ? -59.18288  -20.60313 -96.86749  1.000 22.79954  ? 6   PRO   A CD  1 
ATOM   28   N N   . SER   A 1 7   ? -56.25419  -24.17642 -97.84789  1.000 21.85602  ? 7   SER   A N   1 
ATOM   29   C CA  . SER   A 1 7   ? -54.86643  -24.53305 -98.08198  1.000 24.84508  ? 7   SER   A CA  1 
ATOM   30   C C   . SER   A 1 7   ? -54.56058  -24.39574 -99.56763  1.000 20.91746  ? 7   SER   A C   1 
ATOM   31   O O   . SER   A 1 7   ? -55.24921  -24.99239 -100.40698 1.000 20.41914  ? 7   SER   A O   1 
ATOM   32   C CB  . SER   A 1 7   ? -54.58351  -25.95540 -97.59401  1.000 17.08972  ? 7   SER   A CB  1 
ATOM   33   O OG  . SER   A 1 7   ? -53.42766  -26.48485 -98.22995  1.000 28.79929  ? 7   SER   A OG  1 
ATOM   34   N N   . LEU   A 1 8   ? -53.52286  -23.61164 -99.88010  1.000 19.44917  ? 8   LEU   A N   1 
ATOM   35   C CA  . LEU   A 1 8   ? -53.16865  -23.34689 -101.27066 1.000 19.81103  ? 8   LEU   A CA  1 
ATOM   36   C C   . LEU   A 1 8   ? -53.05506  -24.63543 -102.07152 1.000 17.56093  ? 8   LEU   A C   1 
ATOM   37   O O   . LEU   A 1 8   ? -53.68983  -24.78157 -103.11936 1.000 23.43272  ? 8   LEU   A O   1 
ATOM   38   C CB  . LEU   A 1 8   ? -51.86251  -22.55287 -101.33679 1.000 17.32293  ? 8   LEU   A CB  1 
ATOM   39   C CG  . LEU   A 1 8   ? -51.99197  -21.08667 -100.90645 1.000 24.63053  ? 8   LEU   A CG  1 
ATOM   40   C CD1 . LEU   A 1 8   ? -50.62200  -20.37570 -100.82445 1.000 18.09012  ? 8   LEU   A CD1 1 
ATOM   41   C CD2 . LEU   A 1 8   ? -52.93132  -20.36647 -101.86305 1.000 15.49408  ? 8   LEU   A CD2 1 
ATOM   42   N N   . ARG   A 1 9   ? -52.26174  -25.59188 -101.58883 1.000 20.08910  ? 9   ARG   A N   1 
ATOM   43   C CA  . ARG   A 1 9   ? -52.07682  -26.81700 -102.35956 1.000 21.33371  ? 9   ARG   A CA  1 
ATOM   44   C C   . ARG   A 1 9   ? -53.40079  -27.54755 -102.57583 1.000 20.24657  ? 9   ARG   A C   1 
ATOM   45   O O   . ARG   A 1 9   ? -53.60158  -28.15618 -103.63152 1.000 25.99935  ? 9   ARG   A O   1 
ATOM   46   C CB  . ARG   A 1 9   ? -51.04971  -27.73033 -101.67451 1.000 22.15952  ? 9   ARG   A CB  1 
ATOM   47   C CG  . ARG   A 1 9   ? -51.43808  -28.16216 -100.25734 1.000 21.78620  ? 9   ARG   A CG  1 
ATOM   48   C CD  . ARG   A 1 9   ? -50.56250  -29.28919 -99.72107  1.000 20.46731  ? 9   ARG   A CD  1 
ATOM   49   N NE  . ARG   A 1 9   ? -50.98799  -29.67709 -98.38031  1.000 18.63363  ? 9   ARG   A NE  1 
ATOM   50   C CZ  . ARG   A 1 9   ? -50.47024  -29.17498 -97.26101  1.000 21.87694  ? 9   ARG   A CZ  1 
ATOM   51   N NH1 . ARG   A 1 9   ? -49.49493  -28.28014 -97.31942  1.000 20.47759  ? 9   ARG   A NH1 1 
ATOM   52   N NH2 . ARG   A 1 9   ? -50.92022  -29.56952 -96.08129  1.000 19.06973  ? 9   ARG   A NH2 1 
ATOM   53   N N   . ASP   A 1 10  ? -54.32278  -27.48466 -101.60785 1.000 23.81392  ? 10  ASP   A N   1 
ATOM   54   C CA  . ASP   A 1 10  ? -55.62272  -28.13542 -101.78335 1.000 25.92303  ? 10  ASP   A CA  1 
ATOM   55   C C   . ASP   A 1 10  ? -56.48399  -27.37827 -102.78099 1.000 19.98730  ? 10  ASP   A C   1 
ATOM   56   O O   . ASP   A 1 10  ? -57.10406  -27.98458 -103.66206 1.000 24.26323  ? 10  ASP   A O   1 
ATOM   57   C CB  . ASP   A 1 10  ? -56.35377  -28.24690 -100.44684 1.000 25.88679  ? 10  ASP   A CB  1 
ATOM   58   C CG  . ASP   A 1 10  ? -55.77601  -29.31979 -99.56578  1.000 33.85257  ? 10  ASP   A CG  1 
ATOM   59   O OD1 . ASP   A 1 10  ? -55.29307  -30.33624 -100.11125 1.000 32.57276  ? 10  ASP   A OD1 1 
ATOM   60   O OD2 . ASP   A 1 10  ? -55.78597  -29.13613 -98.32842  1.000 37.47473  ? 10  ASP   A OD2 1 
ATOM   61   N N   . VAL   A 1 11  ? -56.54596  -26.05012 -102.64279 1.000 15.35157  ? 11  VAL   A N   1 
ATOM   62   C CA  . VAL   A 1 11  ? -57.28155  -25.23116 -103.60152 1.000 17.89834  ? 11  VAL   A CA  1 
ATOM   63   C C   . VAL   A 1 11  ? -56.85689  -25.57655 -105.02863 1.000 29.75690  ? 11  VAL   A C   1 
ATOM   64   O O   . VAL   A 1 11  ? -57.69271  -25.77885 -105.91453 1.000 19.45626  ? 11  VAL   A O   1 
ATOM   65   C CB  . VAL   A 1 11  ? -57.06870  -23.74147 -103.29268 1.000 18.26394  ? 11  VAL   A CB  1 
ATOM   66   C CG1 . VAL   A 1 11  ? -57.59008  -22.86818 -104.42611 1.000 22.52823  ? 11  VAL   A CG1 1 
ATOM   67   C CG2 . VAL   A 1 11  ? -57.73318  -23.38890 -101.98263 1.000 13.98681  ? 11  VAL   A CG2 1 
ATOM   68   N N   . PHE   A 1 12  ? -55.54963  -25.71921 -105.26413 1.000 23.09710  ? 12  PHE   A N   1 
ATOM   69   C CA  . PHE   A 1 12  ? -55.06125  -25.96952 -106.61704 1.000 25.14689  ? 12  PHE   A CA  1 
ATOM   70   C C   . PHE   A 1 12  ? -54.70979  -27.43404 -106.87160 1.000 23.51185  ? 12  PHE   A C   1 
ATOM   71   O O   . PHE   A 1 12  ? -54.00857  -27.73907 -107.84266 1.000 21.95526  ? 12  PHE   A O   1 
ATOM   72   C CB  . PHE   A 1 12  ? -53.89134  -25.03668 -106.90375 1.000 16.67120  ? 12  PHE   A CB  1 
ATOM   73   C CG  . PHE   A 1 12  ? -54.29954  -23.59904 -106.91639 1.000 18.45996  ? 12  PHE   A CG  1 
ATOM   74   C CD1 . PHE   A 1 12  ? -55.08424  -23.09108 -107.96133 1.000 17.63264  ? 12  PHE   A CD1 1 
ATOM   75   C CD2 . PHE   A 1 12  ? -53.95878  -22.75904 -105.87145 1.000 13.67228  ? 12  PHE   A CD2 1 
ATOM   76   C CE1 . PHE   A 1 12  ? -55.48015  -21.74658 -107.97579 1.000 13.39568  ? 12  PHE   A CE1 1 
ATOM   77   C CE2 . PHE   A 1 12  ? -54.35316  -21.41591 -105.88450 1.000 15.48091  ? 12  PHE   A CE2 1 
ATOM   78   C CZ  . PHE   A 1 12  ? -55.11359  -20.91118 -106.93753 1.000 10.96345  ? 12  PHE   A CZ  1 
ATOM   79   N N   . ALA   A 1 13  ? -55.25461  -28.34233 -106.05708 1.000 20.03443  ? 13  ALA   A N   1 
ATOM   80   C CA  . ALA   A 1 13  ? -54.95889  -29.76403 -106.17648 1.000 25.11534  ? 13  ALA   A CA  1 
ATOM   81   C C   . ALA   A 1 13  ? -55.10746  -30.26810 -107.60606 1.000 26.66946  ? 13  ALA   A C   1 
ATOM   82   O O   . ALA   A 1 13  ? -54.30887  -31.08976 -108.06491 1.000 32.15601  ? 13  ALA   A O   1 
ATOM   83   C CB  . ALA   A 1 13  ? -55.86631  -30.55733 -105.23516 1.000 20.24514  ? 13  ALA   A CB  1 
ATOM   84   N N   . ASN   A 1 14  ? -56.12019  -29.80207 -108.32664 1.000 24.39829  ? 14  ASN   A N   1 
ATOM   85   C CA  . ASN   A 1 14  ? -56.34699  -30.29878 -109.67818 1.000 32.17667  ? 14  ASN   A CA  1 
ATOM   86   C C   . ASN   A 1 14  ? -55.66353  -29.45737 -110.74172 1.000 29.11459  ? 14  ASN   A C   1 
ATOM   87   O O   . ASN   A 1 14  ? -55.83053  -29.73308 -111.93353 1.000 28.22811  ? 14  ASN   A O   1 
ATOM   88   C CB  . ASN   A 1 14  ? -57.85016  -30.39225 -109.96921 1.000 36.13120  ? 14  ASN   A CB  1 
ATOM   89   C CG  . ASN   A 1 14  ? -58.53036  -31.46144 -109.12811 1.000 46.44250  ? 14  ASN   A CG  1 
ATOM   90   O OD1 . ASN   A 1 14  ? -58.00483  -32.56773 -108.97352 1.000 48.86422  ? 14  ASN   A OD1 1 
ATOM   91   N ND2 . ASN   A 1 14  ? -59.69004  -31.13026 -108.55976 1.000 55.97877  ? 14  ASN   A ND2 1 
ATOM   92   N N   . ASP   A 1 15  ? -54.87955  -28.45965 -110.34751 1.000 22.53683  ? 15  ASP   A N   1 
ATOM   93   C CA  . ASP   A 1 15  ? -54.30536  -27.53352 -111.31338 1.000 28.49956  ? 15  ASP   A CA  1 
ATOM   94   C C   . ASP   A 1 15  ? -52.78878  -27.62120 -111.35656 1.000 24.96556  ? 15  ASP   A C   1 
ATOM   95   O O   . ASP   A 1 15  ? -52.22555  -27.89137 -112.42305 1.000 23.00941  ? 15  ASP   A O   1 
ATOM   96   C CB  . ASP   A 1 15  ? -54.78549  -26.11544 -110.98813 1.000 23.47650  ? 15  ASP   A CB  1 
ATOM   97   C CG  . ASP   A 1 15  ? -56.30667  -26.02844 -110.93699 1.000 29.05409  ? 15  ASP   A CG  1 
ATOM   98   O OD1 . ASP   A 1 15  ? -56.96102  -26.55210 -111.86820 1.000 26.14362  ? 15  ASP   A OD1 1 
ATOM   99   O OD2 . ASP   A 1 15  ? -56.84509  -25.46524 -109.95804 1.000 31.63294  ? 15  ASP   A OD2 1 
ATOM   100  N N   . PHE   A 1 16  ? -52.11513  -27.42454 -110.22660 1.000 21.01984  ? 16  PHE   A N   1 
ATOM   101  C CA  . PHE   A 1 16  ? -50.66099  -27.43812 -110.17929 1.000 16.98540  ? 16  PHE   A CA  1 
ATOM   102  C C   . PHE   A 1 16  ? -50.22286  -27.49221 -108.72385 1.000 22.66734  ? 16  PHE   A C   1 
ATOM   103  O O   . PHE   A 1 16  ? -50.95525  -27.08254 -107.81715 1.000 18.23168  ? 16  PHE   A O   1 
ATOM   104  C CB  . PHE   A 1 16  ? -50.06411  -26.20497 -110.86785 1.000 22.70811  ? 16  PHE   A CB  1 
ATOM   105  C CG  . PHE   A 1 16  ? -50.93352  -24.98600 -110.78202 1.000 19.19264  ? 16  PHE   A CG  1 
ATOM   106  C CD1 . PHE   A 1 16  ? -51.10621  -24.32337 -109.57244 1.000 21.71901  ? 16  PHE   A CD1 1 
ATOM   107  C CD2 . PHE   A 1 16  ? -51.59551  -24.51169 -111.90972 1.000 18.84920  ? 16  PHE   A CD2 1 
ATOM   108  C CE1 . PHE   A 1 16  ? -51.92185  -23.19514 -109.48924 1.000 17.64450  ? 16  PHE   A CE1 1 
ATOM   109  C CE2 . PHE   A 1 16  ? -52.41028  -23.39808 -111.83733 1.000 16.46929  ? 16  PHE   A CE2 1 
ATOM   110  C CZ  . PHE   A 1 16  ? -52.56988  -22.73314 -110.62516 1.000 18.83972  ? 16  PHE   A CZ  1 
ATOM   111  N N   . ARG   A 1 17  ? -49.01736  -28.00333 -108.51176 1.000 19.84281  ? 17  ARG   A N   1 
ATOM   112  C CA  . ARG   A 1 17  ? -48.41794  -27.90377 -107.19241 1.000 22.34953  ? 17  ARG   A CA  1 
ATOM   113  C C   . ARG   A 1 17  ? -48.18030  -26.43483 -106.83315 1.000 20.56338  ? 17  ARG   A C   1 
ATOM   114  O O   . ARG   A 1 17  ? -48.09894  -25.55388 -107.70018 1.000 18.32779  ? 17  ARG   A O   1 
ATOM   115  C CB  . ARG   A 1 17  ? -47.10449  -28.69093 -107.14240 1.000 22.21788  ? 17  ARG   A CB  1 
ATOM   116  C CG  . ARG   A 1 17  ? -47.29407  -30.20088 -107.18011 1.000 22.71639  ? 17  ARG   A CG  1 
ATOM   117  C CD  . ARG   A 1 17  ? -45.98112  -30.98120 -106.92882 1.000 22.67927  ? 17  ARG   A CD  1 
ATOM   118  N NE  . ARG   A 1 17  ? -45.97722  -32.30522 -107.55797 1.000 39.32537  ? 17  ARG   A NE  1 
ATOM   119  C CZ  . ARG   A 1 17  ? -45.89524  -32.50703 -108.87889 1.000 49.21235  ? 17  ARG   A CZ  1 
ATOM   120  N NH1 . ARG   A 1 17  ? -45.82010  -31.47273 -109.70516 1.000 39.08445  ? 17  ARG   A NH1 1 
ATOM   121  N NH2 . ARG   A 1 17  ? -45.88745  -33.73845 -109.38428 1.000 46.59186  ? 17  ARG   A NH2 1 
ATOM   122  N N   . ILE   A 1 18  ? -48.08845  -26.17741 -105.52941 1.000 17.34213  ? 18  ILE   A N   1 
ATOM   123  C CA  . ILE   A 1 18  ? -47.79811  -24.85520 -104.98125 1.000 13.30745  ? 18  ILE   A CA  1 
ATOM   124  C C   . ILE   A 1 18  ? -46.49475  -24.97517 -104.19801 1.000 19.55791  ? 18  ILE   A C   1 
ATOM   125  O O   . ILE   A 1 18  ? -46.38201  -25.82926 -103.30625 1.000 18.19687  ? 18  ILE   A O   1 
ATOM   126  C CB  . ILE   A 1 18  ? -48.93459  -24.35383 -104.07597 1.000 15.81914  ? 18  ILE   A CB  1 
ATOM   127  C CG1 . ILE   A 1 18  ? -50.27322  -24.35886 -104.82348 1.000 14.54523  ? 18  ILE   A CG1 1 
ATOM   128  C CG2 . ILE   A 1 18  ? -48.61230  -22.96783 -103.55669 1.000 13.28390  ? 18  ILE   A CG2 1 
ATOM   129  C CD1 . ILE   A 1 18  ? -50.37023  -23.26930 -105.89262 1.000 13.28788  ? 18  ILE   A CD1 1 
ATOM   130  N N   . GLY   A 1 19  ? -45.51087  -24.12880 -104.52966 1.000 16.48655  ? 19  GLY   A N   1 
ATOM   131  C CA  . GLY   A 1 19  ? -44.18082  -24.23181 -103.97383 1.000 13.85466  ? 19  GLY   A CA  1 
ATOM   132  C C   . GLY   A 1 19  ? -43.75614  -22.96171 -103.25053 1.000 17.94579  ? 19  GLY   A C   1 
ATOM   133  O O   . GLY   A 1 19  ? -44.42772  -21.92789 -103.30349 1.000 16.37673  ? 19  GLY   A O   1 
ATOM   134  N N   . ALA   A 1 20  ? -42.61215  -23.05806 -102.57373 1.000 13.70330  ? 20  ALA   A N   1 
ATOM   135  C CA  . ALA   A 1 20  ? -41.99374  -21.93626 -101.88397 1.000 13.88830  ? 20  ALA   A CA  1 
ATOM   136  C C   . ALA   A 1 20  ? -40.48957  -22.14018 -101.89927 1.000 17.28882  ? 20  ALA   A C   1 
ATOM   137  O O   . ALA   A 1 20  ? -40.01539  -23.26606 -101.72868 1.000 14.83094  ? 20  ALA   A O   1 
ATOM   138  C CB  . ALA   A 1 20  ? -42.47401  -21.81304 -100.43005 1.000 8.79005   ? 20  ALA   A CB  1 
ATOM   139  N N   . ALA   A 1 21  ? -39.75353  -21.05217 -102.10657 1.000 12.99148  ? 21  ALA   A N   1 
ATOM   140  C CA  . ALA   A 1 21  ? -38.30844  -21.06997 -101.95556 1.000 16.55477  ? 21  ALA   A CA  1 
ATOM   141  C C   . ALA   A 1 21  ? -37.97130  -20.87123 -100.48743 1.000 16.60036  ? 21  ALA   A C   1 
ATOM   142  O O   . ALA   A 1 21  ? -38.54006  -19.99690 -99.82991  1.000 23.08387  ? 21  ALA   A O   1 
ATOM   143  C CB  . ALA   A 1 21  ? -37.66590  -19.98086 -102.80594 1.000 14.70716  ? 21  ALA   A CB  1 
ATOM   144  N N   . VAL   A 1 22  ? -37.07134  -21.70069 -99.95863  1.000 20.93366  ? 22  VAL   A N   1 
ATOM   145  C CA  . VAL   A 1 22  ? -36.75469  -21.70144 -98.53370  1.000 16.98590  ? 22  VAL   A CA  1 
ATOM   146  C C   . VAL   A 1 22  ? -35.24882  -21.84180 -98.34456  1.000 22.08251  ? 22  VAL   A C   1 
ATOM   147  O O   . VAL   A 1 22  ? -34.48790  -22.06132 -99.29154  1.000 17.90102  ? 22  VAL   A O   1 
ATOM   148  C CB  . VAL   A 1 22  ? -37.47201  -22.84256 -97.77868  1.000 20.39271  ? 22  VAL   A CB  1 
ATOM   149  C CG1 . VAL   A 1 22  ? -38.99787  -22.71796 -97.89068  1.000 16.86089  ? 22  VAL   A CG1 1 
ATOM   150  C CG2 . VAL   A 1 22  ? -36.99243  -24.18160 -98.28404  1.000 16.37039  ? 22  VAL   A CG2 1 
ATOM   151  N N   . ASN   A 1 23  ? -34.83366  -21.70828 -97.09093  1.000 20.69182  ? 23  ASN   A N   1 
ATOM   152  C CA  . ASN   A 1 23  ? -33.52444  -22.10640 -96.59583  1.000 29.14756  ? 23  ASN   A CA  1 
ATOM   153  C C   . ASN   A 1 23  ? -33.75343  -22.66959 -95.19219  1.000 27.65005  ? 23  ASN   A C   1 
ATOM   154  O O   . ASN   A 1 23  ? -34.89953  -22.67377 -94.73064  1.000 23.14822  ? 23  ASN   A O   1 
ATOM   155  C CB  . ASN   A 1 23  ? -32.54448  -20.92869 -96.61684  1.000 27.55384  ? 23  ASN   A CB  1 
ATOM   156  C CG  . ASN   A 1 23  ? -33.01287  -19.75755 -95.79089  1.000 28.65501  ? 23  ASN   A CG  1 
ATOM   157  O OD1 . ASN   A 1 23  ? -33.50383  -19.91394 -94.66295  1.000 27.33666  ? 23  ASN   A OD1 1 
ATOM   158  N ND2 . ASN   A 1 23  ? -32.84852  -18.56259 -96.34231  1.000 20.62915  ? 23  ASN   A ND2 1 
ATOM   159  N N   . PRO   A 1 24  ? -32.73056  -23.18237 -94.49468  1.000 30.75137  ? 24  PRO   A N   1 
ATOM   160  C CA  . PRO   A 1 24  ? -32.99121  -23.75526 -93.15994  1.000 24.16780  ? 24  PRO   A CA  1 
ATOM   161  C C   . PRO   A 1 24  ? -33.53723  -22.76311 -92.14386  1.000 24.51671  ? 24  PRO   A C   1 
ATOM   162  O O   . PRO   A 1 24  ? -34.36838  -23.14799 -91.31231  1.000 26.05120  ? 24  PRO   A O   1 
ATOM   163  C CB  . PRO   A 1 24  ? -31.61835  -24.29941 -92.74872  1.000 25.80266  ? 24  PRO   A CB  1 
ATOM   164  C CG  . PRO   A 1 24  ? -31.01515  -24.72185 -94.05908  1.000 32.41770  ? 24  PRO   A CG  1 
ATOM   165  C CD  . PRO   A 1 24  ? -31.41926  -23.62100 -95.01737  1.000 30.40350  ? 24  PRO   A CD  1 
ATOM   166  N N   . VAL   A 1 25  ? -33.11864  -21.49916 -92.19442  1.000 19.83613  ? 25  VAL   A N   1 
ATOM   167  C CA  . VAL   A 1 25  ? -33.68341  -20.48986 -91.30032  1.000 23.01935  ? 25  VAL   A CA  1 
ATOM   168  C C   . VAL   A 1 25  ? -35.17468  -20.27075 -91.58630  1.000 27.87550  ? 25  VAL   A C   1 
ATOM   169  O O   . VAL   A 1 25  ? -36.01988  -20.39639 -90.68921  1.000 24.92730  ? 25  VAL   A O   1 
ATOM   170  C CB  . VAL   A 1 25  ? -32.87866  -19.18414 -91.40828  1.000 27.76390  ? 25  VAL   A CB  1 
ATOM   171  C CG1 . VAL   A 1 25  ? -33.63729  -18.04392 -90.76534  1.000 23.59287  ? 25  VAL   A CG1 1 
ATOM   172  C CG2 . VAL   A 1 25  ? -31.51409  -19.37214 -90.74070  1.000 23.66910  ? 25  VAL   A CG2 1 
ATOM   173  N N   . THR   A 1 26  ? -35.52993  -19.95664 -92.84067  1.000 22.96274  ? 26  THR   A N   1 
ATOM   174  C CA  . THR   A 1 26  ? -36.93738  -19.66666 -93.12479  1.000 21.68614  ? 26  THR   A CA  1 
ATOM   175  C C   . THR   A 1 26  ? -37.81102  -20.89197 -92.93023  1.000 20.79446  ? 26  THR   A C   1 
ATOM   176  O O   . THR   A 1 26  ? -38.98742  -20.75377 -92.57774  1.000 24.91484  ? 26  THR   A O   1 
ATOM   177  C CB  . THR   A 1 26  ? -37.13333  -19.12211 -94.54189  1.000 25.21201  ? 26  THR   A CB  1 
ATOM   178  O OG1 . THR   A 1 26  ? -36.84202  -20.14642 -95.50505  1.000 28.69143  ? 26  THR   A OG1 1 
ATOM   179  C CG2 . THR   A 1 26  ? -36.25143  -17.89446 -94.78264  1.000 21.93495  ? 26  THR   A CG2 1 
ATOM   180  N N   . ILE   A 1 27  ? -37.26566  -22.09334 -93.13960  1.000 19.33889  ? 27  ILE   A N   1 
ATOM   181  C CA  . ILE   A 1 27  ? -38.03232  -23.29492 -92.82139  1.000 24.62543  ? 27  ILE   A CA  1 
ATOM   182  C C   . ILE   A 1 27  ? -38.48309  -23.26474 -91.36701  1.000 27.49114  ? 27  ILE   A C   1 
ATOM   183  O O   . ILE   A 1 27  ? -39.62990  -23.59365 -91.05728  1.000 27.96459  ? 27  ILE   A O   1 
ATOM   184  C CB  . ILE   A 1 27  ? -37.22236  -24.56600 -93.12124  1.000 28.77912  ? 27  ILE   A CB  1 
ATOM   185  C CG1 . ILE   A 1 27  ? -37.22238  -24.87241 -94.61553  1.000 26.14947  ? 27  ILE   A CG1 1 
ATOM   186  C CG2 . ILE   A 1 27  ? -37.82025  -25.75060 -92.36688  1.000 26.51195  ? 27  ILE   A CG2 1 
ATOM   187  C CD1 . ILE   A 1 27  ? -36.23449  -25.97434 -94.97606  1.000 20.66352  ? 27  ILE   A CD1 1 
ATOM   188  N N   . GLU   A 1 28  ? -37.59284  -22.85921 -90.45391  1.000 21.45977  ? 28  GLU   A N   1 
ATOM   189  C CA  . GLU   A 1 28  ? -37.97233  -22.72857 -89.04755  1.000 26.96653  ? 28  GLU   A CA  1 
ATOM   190  C C   . GLU   A 1 28  ? -38.94486  -21.57599 -88.84796  1.000 24.79348  ? 28  GLU   A C   1 
ATOM   191  O O   . GLU   A 1 28  ? -39.98762  -21.72989 -88.20392  1.000 25.80388  ? 28  GLU   A O   1 
ATOM   192  C CB  . GLU   A 1 28  ? -36.72592  -22.51998 -88.17484  1.000 27.98033  ? 28  GLU   A CB  1 
ATOM   193  C CG  . GLU   A 1 28  ? -35.84989  -23.76031 -88.04335  1.000 34.52478  ? 28  GLU   A CG  1 
ATOM   194  C CD  . GLU   A 1 28  ? -36.65789  -25.00616 -87.67270  1.000 49.47029  ? 28  GLU   A CD  1 
ATOM   195  O OE1 . GLU   A 1 28  ? -37.43879  -24.94891 -86.68876  1.000 47.00873  ? 28  GLU   A OE1 1 
ATOM   196  O OE2 . GLU   A 1 28  ? -36.52356  -26.03411 -88.37778  1.000 43.29970  ? 28  GLU   A OE2 1 
ATOM   197  N N   . MET   A 1 29  ? -38.61873  -20.41359 -89.41318  1.000 23.27697  ? 29  MET   A N   1 
ATOM   198  C CA  . MET   A 1 29  ? -39.38003  -19.19797 -89.15523  1.000 20.14085  ? 29  MET   A CA  1 
ATOM   199  C C   . MET   A 1 29  ? -40.78309  -19.25886 -89.75163  1.000 21.42056  ? 29  MET   A C   1 
ATOM   200  O O   . MET   A 1 29  ? -41.69428  -18.59523 -89.24670  1.000 23.02707  ? 29  MET   A O   1 
ATOM   201  C CB  . MET   A 1 29  ? -38.59026  -18.00367 -89.70044  1.000 25.38743  ? 29  MET   A CB  1 
ATOM   202  C CG  . MET   A 1 29  ? -39.23103  -16.63868 -89.54714  1.000 30.66561  ? 29  MET   A CG  1 
ATOM   203  S SD  . MET   A 1 29  ? -38.12672  -15.36611 -90.20501  1.000 46.65024  ? 29  MET   A SD  1 
ATOM   204  C CE  . MET   A 1 29  ? -38.51584  -15.41464 -91.95390  1.000 26.27689  ? 29  MET   A CE  1 
ATOM   205  N N   . GLN   A 1 30  ? -40.98689  -20.05137 -90.80729  1.000 20.89486  ? 30  GLN   A N   1 
ATOM   206  C CA  . GLN   A 1 30  ? -42.27075  -20.10458 -91.50114  1.000 19.72832  ? 30  GLN   A CA  1 
ATOM   207  C C   . GLN   A 1 30  ? -42.81580  -21.52361 -91.56654  1.000 21.39050  ? 30  GLN   A C   1 
ATOM   208  O O   . GLN   A 1 30  ? -43.64058  -21.82741 -92.43887  1.000 20.91338  ? 30  GLN   A O   1 
ATOM   209  C CB  . GLN   A 1 30  ? -42.14030  -19.51936 -92.91038  1.000 11.65565  ? 30  GLN   A CB  1 
ATOM   210  C CG  . GLN   A 1 30  ? -41.72354  -18.04507 -92.92780  1.000 11.65421  ? 30  GLN   A CG  1 
ATOM   211  C CD  . GLN   A 1 30  ? -41.19053  -17.57826 -94.27870  1.000 23.04318  ? 30  GLN   A CD  1 
ATOM   212  O OE1 . GLN   A 1 30  ? -40.57869  -18.35198 -95.03833  1.000 18.94578  ? 30  GLN   A OE1 1 
ATOM   213  N NE2 . GLN   A 1 30  ? -41.42201  -16.30091 -94.58915  1.000 19.80219  ? 30  GLN   A NE2 1 
ATOM   214  N N   . LYS   A 1 31  ? -42.37161  -22.39657 -90.65574  1.000 17.84719  ? 31  LYS   A N   1 
ATOM   215  C CA  . LYS   A 1 31  ? -42.67614  -23.82033 -90.76820  1.000 22.85373  ? 31  LYS   A CA  1 
ATOM   216  C C   . LYS   A 1 31  ? -44.17088  -24.07414 -90.95267  1.000 26.31013  ? 31  LYS   A C   1 
ATOM   217  O O   . LYS   A 1 31  ? -44.57711  -24.83278 -91.84546  1.000 26.97352  ? 31  LYS   A O   1 
ATOM   218  C CB  . LYS   A 1 31  ? -42.14388  -24.55704 -89.53988  1.000 22.28399  ? 31  LYS   A CB  1 
ATOM   219  C CG  . LYS   A 1 31  ? -42.02939  -26.06230 -89.72647  1.000 33.94511  ? 31  LYS   A CG  1 
ATOM   220  C CD  . LYS   A 1 31  ? -41.37501  -26.72696 -88.51826  1.000 39.57801  ? 31  LYS   A CD  1 
ATOM   221  C CE  . LYS   A 1 31  ? -39.89297  -26.39846 -88.43852  1.000 38.65916  ? 31  LYS   A CE  1 
ATOM   222  N NZ  . LYS   A 1 31  ? -39.32361  -26.79619 -87.11637  1.000 42.39674  ? 31  LYS   A NZ  1 
ATOM   223  N N   . GLN   A 1 32  ? -45.00824  -23.42453 -90.13506  1.000 19.95539  ? 32  GLN   A N   1 
ATOM   224  C CA  . GLN   A 1 32  ? -46.43831  -23.72783 -90.16312  1.000 24.25574  ? 32  GLN   A CA  1 
ATOM   225  C C   . GLN   A 1 32  ? -47.07625  -23.35483 -91.49625  1.000 19.75455  ? 32  GLN   A C   1 
ATOM   226  O O   . GLN   A 1 32  ? -47.94075  -24.08933 -92.00104  1.000 15.04064  ? 32  GLN   A O   1 
ATOM   227  C CB  . GLN   A 1 32  ? -47.16652  -23.01524 -89.02840  1.000 26.25369  ? 32  GLN   A CB  1 
ATOM   228  C CG  . GLN   A 1 32  ? -48.51071  -23.64389 -88.77843  1.000 26.30569  ? 32  GLN   A CG  1 
ATOM   229  C CD  . GLN   A 1 32  ? -48.36474  -25.09438 -88.36619  1.000 34.48062  ? 32  GLN   A CD  1 
ATOM   230  O OE1 . GLN   A 1 32  ? -47.57796  -25.40545 -87.46282  1.000 30.82080  ? 32  GLN   A OE1 1 
ATOM   231  N NE2 . GLN   A 1 32  ? -49.10872  -25.99458 -89.02669  1.000 27.15056  ? 32  GLN   A NE2 1 
ATOM   232  N N   . LEU   A 1 33  ? -46.67855  -22.20904 -92.06707  1.000 19.31808  ? 33  LEU   A N   1 
ATOM   233  C CA  . LEU   A 1 33  ? -47.21210  -21.78982 -93.36447  1.000 21.50840  ? 33  LEU   A CA  1 
ATOM   234  C C   . LEU   A 1 33  ? -46.91949  -22.83521 -94.42150  1.000 23.65467  ? 33  LEU   A C   1 
ATOM   235  O O   . LEU   A 1 33  ? -47.81728  -23.26005 -95.16499  1.000 21.55959  ? 33  LEU   A O   1 
ATOM   236  C CB  . LEU   A 1 33  ? -46.60286  -20.45480 -93.78648  1.000 18.40063  ? 33  LEU   A CB  1 
ATOM   237  C CG  . LEU   A 1 33  ? -47.18374  -19.17293 -93.21552  1.000 27.88522  ? 33  LEU   A CG  1 
ATOM   238  C CD1 . LEU   A 1 33  ? -46.39411  -17.97720 -93.71622  1.000 22.62456  ? 33  LEU   A CD1 1 
ATOM   239  C CD2 . LEU   A 1 33  ? -48.64886  -19.06216 -93.59275  1.000 20.13456  ? 33  LEU   A CD2 1 
ATOM   240  N N   . LEU   A 1 34  ? -45.65322  -23.26934 -94.48210  1.000 19.75242  ? 34  LEU   A N   1 
ATOM   241  C CA  . LEU   A 1 34  ? -45.23177  -24.27207 -95.45024  1.000 18.74898  ? 34  LEU   A CA  1 
ATOM   242  C C   . LEU   A 1 34  ? -46.02293  -25.55113 -95.26505  1.000 22.07476  ? 34  LEU   A C   1 
ATOM   243  O O   . LEU   A 1 34  ? -46.58059  -26.10068 -96.22791  1.000 21.64940  ? 34  LEU   A O   1 
ATOM   244  C CB  . LEU   A 1 34  ? -43.73092  -24.53349 -95.29610  1.000 20.18452  ? 34  LEU   A CB  1 
ATOM   245  C CG  . LEU   A 1 34  ? -42.89193  -23.26165 -95.44492  1.000 17.88324  ? 34  LEU   A CG  1 
ATOM   246  C CD1 . LEU   A 1 34  ? -41.50844  -23.39727 -94.81383  1.000 19.43667  ? 34  LEU   A CD1 1 
ATOM   247  C CD2 . LEU   A 1 34  ? -42.79381  -22.88219 -96.92203  1.000 7.23469   ? 34  LEU   A CD2 1 
ATOM   248  N N   . ILE   A 1 35  ? -46.10626  -26.02345 -94.01763  1.000 15.14945  ? 35  ILE   A N   1 
ATOM   249  C CA  . ILE   A 1 35  ? -46.83092  -27.25722 -93.74504  1.000 15.14886  ? 35  ILE   A CA  1 
ATOM   250  C C   . ILE   A 1 35  ? -48.29717  -27.12233 -94.12385  1.000 22.60018  ? 35  ILE   A C   1 
ATOM   251  O O   . ILE   A 1 35  ? -48.90133  -28.08170 -94.62446  1.000 21.59542  ? 35  ILE   A O   1 
ATOM   252  C CB  . ILE   A 1 35  ? -46.65201  -27.65451 -92.27036  1.000 27.98948  ? 35  ILE   A CB  1 
ATOM   253  C CG1 . ILE   A 1 35  ? -45.21371  -28.11238 -92.02667  1.000 26.32361  ? 35  ILE   A CG1 1 
ATOM   254  C CG2 . ILE   A 1 35  ? -47.64210  -28.73568 -91.87978  1.000 18.72203  ? 35  ILE   A CG2 1 
ATOM   255  C CD1 . ILE   A 1 35  ? -44.88110  -28.26533 -90.56489  1.000 29.90817  ? 35  ILE   A CD1 1 
ATOM   256  N N   . ASP   A 1 36  ? -48.88891  -25.93178 -93.93896  1.000 16.40439  ? 36  ASP   A N   1 
ATOM   257  C CA  . ASP   A 1 36  ? -50.31376  -25.78829 -94.24472  1.000 27.55211  ? 36  ASP   A CA  1 
ATOM   258  C C   . ASP   A 1 36  ? -50.59947  -25.56471 -95.71981  1.000 22.75651  ? 36  ASP   A C   1 
ATOM   259  O O   . ASP   A 1 36  ? -51.70606  -25.88199 -96.16291  1.000 21.06735  ? 36  ASP   A O   1 
ATOM   260  C CB  . ASP   A 1 36  ? -50.95100  -24.62850 -93.46860  1.000 26.56897  ? 36  ASP   A CB  1 
ATOM   261  C CG  . ASP   A 1 36  ? -51.03788  -24.89600 -91.97610  1.000 29.27092  ? 36  ASP   A CG  1 
ATOM   262  O OD1 . ASP   A 1 36  ? -51.03067  -26.08659 -91.57521  1.000 24.15798  ? 36  ASP   A OD1 1 
ATOM   263  O OD2 . ASP   A 1 36  ? -51.10232  -23.90365 -91.21092  1.000 31.25397  ? 36  ASP   A OD2 1 
ATOM   264  N N   . HIS   A 1 37  ? -49.64616  -25.04320 -96.49828  1.000 22.33939  ? 37  HIS   A N   1 
ATOM   265  C CA  . HIS   A 1 37  ? -50.01329  -24.55502 -97.82185  1.000 20.02103  ? 37  HIS   A CA  1 
ATOM   266  C C   . HIS   A 1 37  ? -49.27235  -25.17823 -99.00101  1.000 22.97143  ? 37  HIS   A C   1 
ATOM   267  O O   . HIS   A 1 37  ? -49.89483  -25.32923 -100.05232 1.000 20.25142  ? 37  HIS   A O   1 
ATOM   268  C CB  . HIS   A 1 37  ? -49.86192  -23.02743 -97.87168  1.000 17.27584  ? 37  HIS   A CB  1 
ATOM   269  C CG  . HIS   A 1 37  ? -50.87117  -22.31528 -97.02773  1.000 20.81915  ? 37  HIS   A CG  1 
ATOM   270  N ND1 . HIS   A 1 37  ? -52.21508  -22.31624 -97.32861  1.000 22.83625  ? 37  HIS   A ND1 1 
ATOM   271  C CD2 . HIS   A 1 37  ? -50.74362  -21.62593 -95.86799  1.000 19.26531  ? 37  HIS   A CD2 1 
ATOM   272  C CE1 . HIS   A 1 37  ? -52.86852  -21.62922 -96.40699  1.000 21.81319  ? 37  HIS   A CE1 1 
ATOM   273  N NE2 . HIS   A 1 37  ? -51.99890  -21.20243 -95.50876  1.000 23.92282  ? 37  HIS   A NE2 1 
ATOM   274  N N   . VAL   A 1 38  ? -47.97180  -25.55237 -98.88062  1.000 19.67638  ? 38  VAL   A N   1 
ATOM   275  C CA  . VAL   A 1 38  ? -47.21037  -25.93867 -100.07064 1.000 15.79019  ? 38  VAL   A CA  1 
ATOM   276  C C   . VAL   A 1 38  ? -47.10780  -27.45437 -100.17130 1.000 18.47469  ? 38  VAL   A C   1 
ATOM   277  O O   . VAL   A 1 38  ? -47.07480  -28.17265 -99.16445  1.000 16.67556  ? 38  VAL   A O   1 
ATOM   278  C CB  . VAL   A 1 38  ? -45.80234  -25.29859 -100.09700 1.000 17.88486  ? 38  VAL   A CB  1 
ATOM   279  C CG1 . VAL   A 1 38  ? -45.89955  -23.78248 -100.03092 1.000 16.93985  ? 38  VAL   A CG1 1 
ATOM   280  C CG2 . VAL   A 1 38  ? -44.89286  -25.86596 -99.00548  1.000 11.24070  ? 38  VAL   A CG2 1 
ATOM   281  N N   . ASN   A 1 39  ? -47.03040  -27.95694 -101.40885 1.000 20.64675  ? 39  ASN   A N   1 
ATOM   282  C CA  . ASN   A 1 39  ? -46.61674  -29.33995 -101.63537 1.000 15.76578  ? 39  ASN   A CA  1 
ATOM   283  C C   . ASN   A 1 39  ? -45.35546  -29.40572 -102.49373 1.000 16.78271  ? 39  ASN   A C   1 
ATOM   284  O O   . ASN   A 1 39  ? -45.10456  -30.40563 -103.16849 1.000 20.00701  ? 39  ASN   A O   1 
ATOM   285  C CB  . ASN   A 1 39  ? -47.74287  -30.17412 -102.25038 1.000 12.98119  ? 39  ASN   A CB  1 
ATOM   286  C CG  . ASN   A 1 39  ? -48.35470  -29.52845 -103.47823 1.000 22.77770  ? 39  ASN   A CG  1 
ATOM   287  O OD1 . ASN   A 1 39  ? -47.78675  -28.59816 -104.05238 1.000 23.79044  ? 39  ASN   A OD1 1 
ATOM   288  N ND2 . ASN   A 1 39  ? -49.52065  -30.02713 -103.89419 1.000 15.72983  ? 39  ASN   A ND2 1 
ATOM   289  N N   . SER   A 1 40  ? -44.54800  -28.34823 -102.46967 1.000 16.66370  ? 40  SER   A N   1 
ATOM   290  C CA  . SER   A 1 40  ? -43.31680  -28.29482 -103.25364 1.000 13.05330  ? 40  SER   A CA  1 
ATOM   291  C C   . SER   A 1 40  ? -42.37050  -27.28499 -102.62425 1.000 15.29330  ? 40  SER   A C   1 
ATOM   292  O O   . SER   A 1 40  ? -42.80200  -26.25672 -102.09953 1.000 14.07440  ? 40  SER   A O   1 
ATOM   293  C CB  . SER   A 1 40  ? -43.57612  -27.91559 -104.71252 1.000 13.25898  ? 40  SER   A CB  1 
ATOM   294  O OG  . SER   A 1 40  ? -42.36423  -27.88968 -105.43554 1.000 13.78561  ? 40  SER   A OG  1 
ATOM   295  N N   . ILE   A 1 41  ? -41.07513  -27.57974 -102.70739 1.000 13.53634  ? 41  ILE   A N   1 
ATOM   296  C CA  . ILE   A 1 41  ? -40.04057  -26.79897 -102.04498 1.000 12.04557  ? 41  ILE   A CA  1 
ATOM   297  C C   . ILE   A 1 41  ? -38.90882  -26.55811 -103.03240 1.000 11.79154  ? 41  ILE   A C   1 
ATOM   298  O O   . ILE   A 1 41  ? -38.56197  -27.43873 -103.82724 1.000 12.98061  ? 41  ILE   A O   1 
ATOM   299  C CB  . ILE   A 1 41  ? -39.53331  -27.51929 -100.77097 1.000 12.77367  ? 41  ILE   A CB  1 
ATOM   300  C CG1 . ILE   A 1 41  ? -40.57929  -27.41792 -99.66382  1.000 19.65339  ? 41  ILE   A CG1 1 
ATOM   301  C CG2 . ILE   A 1 41  ? -38.24708  -26.92843 -100.26899 1.000 10.89230  ? 41  ILE   A CG2 1 
ATOM   302  C CD1 . ILE   A 1 41  ? -40.83986  -26.00366 -99.23349  1.000 16.88807  ? 41  ILE   A CD1 1 
ATOM   303  N N   . THR   A 1 42  ? -38.33993  -25.36480 -102.98733 1.000 11.88140  ? 42  THR   A N   1 
ATOM   304  C CA  . THR   A 1 42  ? -37.13612  -25.04027 -103.73101 1.000 12.26052  ? 42  THR   A CA  1 
ATOM   305  C C   . THR   A 1 42  ? -36.16029  -24.38738 -102.76748 1.000 16.58094  ? 42  THR   A C   1 
ATOM   306  O O   . THR   A 1 42  ? -36.57490  -23.64669 -101.86563 1.000 16.70740  ? 42  THR   A O   1 
ATOM   307  C CB  . THR   A 1 42  ? -37.43493  -24.08914 -104.91191 1.000 15.46987  ? 42  THR   A CB  1 
ATOM   308  O OG1 . THR   A 1 42  ? -38.37124  -24.70302 -105.81200 1.000 12.97914  ? 42  THR   A OG1 1 
ATOM   309  C CG2 . THR   A 1 42  ? -36.14620  -23.72556 -105.65157 1.000 11.86966  ? 42  THR   A CG2 1 
ATOM   310  N N   . ALA   A 1 43  ? -34.86942  -24.67171 -102.94895 1.000 12.36726  ? 43  ALA   A N   1 
ATOM   311  C CA  . ALA   A 1 43  ? -33.82691  -24.02775 -102.16048 1.000 12.60162  ? 43  ALA   A CA  1 
ATOM   312  C C   . ALA   A 1 43  ? -33.56690  -22.63287 -102.71384 1.000 11.77099  ? 43  ALA   A C   1 
ATOM   313  O O   . ALA   A 1 43  ? -33.21641  -22.47773 -103.88563 1.000 13.37180  ? 43  ALA   A O   1 
ATOM   314  C CB  . ALA   A 1 43  ? -32.54402  -24.85706 -102.16865 1.000 11.28140  ? 43  ALA   A CB  1 
ATOM   315  N N   . GLU   A 1 44  ? -33.73688  -21.61311 -101.88222 1.000 11.40476  ? 44  GLU   A N   1 
ATOM   316  C CA  . GLU   A 1 44  ? -33.54026  -20.25938 -102.38580 1.000 16.42013  ? 44  GLU   A CA  1 
ATOM   317  C C   . GLU   A 1 44  ? -32.08235  -20.01172 -102.78159 1.000 17.97400  ? 44  GLU   A C   1 
ATOM   318  O O   . GLU   A 1 44  ? -31.81488  -19.30452 -103.76414 1.000 20.26511  ? 44  GLU   A O   1 
ATOM   319  C CB  . GLU   A 1 44  ? -34.01097  -19.24049 -101.34461 1.000 16.15937  ? 44  GLU   A CB  1 
ATOM   320  C CG  . GLU   A 1 44  ? -33.93985  -17.81256 -101.83036 1.000 14.88511  ? 44  GLU   A CG  1 
ATOM   321  C CD  . GLU   A 1 44  ? -34.30953  -16.81974 -100.75119 1.000 18.64279  ? 44  GLU   A CD  1 
ATOM   322  O OE1 . GLU   A 1 44  ? -34.59903  -17.24713 -99.61445  1.000 17.41955  ? 44  GLU   A OE1 1 
ATOM   323  O OE2 . GLU   A 1 44  ? -34.30743  -15.60600 -101.03687 1.000 20.21161  ? 44  GLU   A OE2 1 
ATOM   324  N N   . ASN   A 1 45  ? -31.12482  -20.59062 -102.04230 1.000 15.62308  ? 45  ASN   A N   1 
ATOM   325  C CA  . ASN   A 1 45  ? -29.70209  -20.40763 -102.34638 1.000 14.51551  ? 45  ASN   A CA  1 
ATOM   326  C C   . ASN   A 1 45  ? -28.85063  -21.65672 -102.18917 1.000 17.30339  ? 45  ASN   A C   1 
ATOM   327  O O   . ASN   A 1 45  ? -27.78683  -21.72890 -102.81330 1.000 18.28807  ? 45  ASN   A O   1 
ATOM   328  C CB  . ASN   A 1 45  ? -29.10047  -19.31131 -101.45660 1.000 15.52365  ? 45  ASN   A CB  1 
ATOM   329  C CG  . ASN   A 1 45  ? -29.53485  -17.93354 -101.87320 1.000 16.53194  ? 45  ASN   A CG  1 
ATOM   330  O OD1 . ASN   A 1 45  ? -29.22805  -17.49860 -102.97397 1.000 19.93609  ? 45  ASN   A OD1 1 
ATOM   331  N ND2 . ASN   A 1 45  ? -30.28196  -17.24842 -101.01138 1.000 11.95936  ? 45  ASN   A ND2 1 
ATOM   332  N N   . HIS   A 1 46  ? -29.25731  -22.64332 -101.39906 1.000 14.62894  ? 46  HIS   A N   1 
ATOM   333  C CA  . HIS   A 1 46  ? -28.32578  -23.63879 -100.89546 1.000 14.07030  ? 46  HIS   A CA  1 
ATOM   334  C C   . HIS   A 1 46  ? -28.14203  -24.83227 -101.81980 1.000 17.27013  ? 46  HIS   A C   1 
ATOM   335  O O   . HIS   A 1 46  ? -27.48827  -25.80547 -101.43741 1.000 20.84455  ? 46  HIS   A O   1 
ATOM   336  C CB  . HIS   A 1 46  ? -28.75356  -24.06458 -99.49494  1.000 13.45590  ? 46  HIS   A CB  1 
ATOM   337  C CG  . HIS   A 1 46  ? -28.43492  -23.01836 -98.48012  1.000 24.00626  ? 46  HIS   A CG  1 
ATOM   338  N ND1 . HIS   A 1 46  ? -29.39459  -22.19350 -97.93400  1.000 24.61853  ? 46  HIS   A ND1 1 
ATOM   339  C CD2 . HIS   A 1 46  ? -27.24312  -22.56984 -98.01618  1.000 21.72596  ? 46  HIS   A CD2 1 
ATOM   340  C CE1 . HIS   A 1 46  ? -28.81697  -21.32898 -97.11869  1.000 26.49670  ? 46  HIS   A CE1 1 
ATOM   341  N NE2 . HIS   A 1 46  ? -27.51057  -21.53115 -97.15632  1.000 33.04688  ? 46  HIS   A NE2 1 
ATOM   342  N N   . MET   A 1 47  ? -28.66016  -24.76499 -103.03565 1.000 11.10077  ? 47  MET   A N   1 
ATOM   343  C CA  . MET   A 1 47  ? -28.31677  -25.73344 -104.05385 1.000 12.86222  ? 47  MET   A CA  1 
ATOM   344  C C   . MET   A 1 47  ? -27.66107  -25.05700 -105.24356 1.000 14.09638  ? 47  MET   A C   1 
ATOM   345  O O   . MET   A 1 47  ? -27.53411  -25.67344 -106.30569 1.000 14.47265  ? 47  MET   A O   1 
ATOM   346  C CB  . MET   A 1 47  ? -29.55645  -26.52696 -104.47184 1.000 14.64016  ? 47  MET   A CB  1 
ATOM   347  C CG  . MET   A 1 47  ? -30.02084  -27.50704 -103.39878 1.000 13.16303  ? 47  MET   A CG  1 
ATOM   348  S SD  . MET   A 1 47  ? -31.29066  -28.62940 -104.00322 1.000 18.12001  ? 47  MET   A SD  1 
ATOM   349  C CE  . MET   A 1 47  ? -31.81850  -29.39662 -102.47067 1.000 12.31936  ? 47  MET   A CE  1 
ATOM   350  N N   . LYS   A 1 48  ? -27.26887  -23.79505 -105.10280 1.000 15.96355  ? 48  LYS   A N   1 
ATOM   351  C CA  . LYS   A 1 48  ? -26.44148  -23.15693 -106.11713 1.000 21.06914  ? 48  LYS   A CA  1 
ATOM   352  C C   . LYS   A 1 48  ? -24.99530  -23.61589 -105.95958 1.000 19.58708  ? 48  LYS   A C   1 
ATOM   353  O O   . LYS   A 1 48  ? -24.59571  -24.12521 -104.90878 1.000 17.60349  ? 48  LYS   A O   1 
ATOM   354  C CB  . LYS   A 1 48  ? -26.54229  -21.63851 -106.01595 1.000 15.94379  ? 48  LYS   A CB  1 
ATOM   355  C CG  . LYS   A 1 48  ? -27.95594  -21.14859 -106.21683 1.000 18.28508  ? 48  LYS   A CG  1 
ATOM   356  C CD  . LYS   A 1 48  ? -28.13636  -19.69151 -105.83784 1.000 22.78991  ? 48  LYS   A CD  1 
ATOM   357  C CE  . LYS   A 1 48  ? -29.57022  -19.24198 -106.12044 1.000 17.60119  ? 48  LYS   A CE  1 
ATOM   358  N NZ  . LYS   A 1 48  ? -29.79119  -17.84383 -105.66149 1.000 20.55640  ? 48  LYS   A NZ  1 
ATOM   359  N N   . PHE   A 1 49  ? -24.21072  -23.43180 -107.02747 1.000 22.40408  ? 49  PHE   A N   1 
ATOM   360  C CA  . PHE   A 1 49  ? -22.84677  -23.95986 -107.06974 1.000 22.66494  ? 49  PHE   A CA  1 
ATOM   361  C C   . PHE   A 1 49  ? -22.01885  -23.51911 -105.85704 1.000 18.75662  ? 49  PHE   A C   1 
ATOM   362  O O   . PHE   A 1 49  ? -21.36336  -24.34318 -105.20729 1.000 15.50647  ? 49  PHE   A O   1 
ATOM   363  C CB  . PHE   A 1 49  ? -22.17336  -23.53309 -108.38003 1.000 22.98196  ? 49  PHE   A CB  1 
ATOM   364  C CG  . PHE   A 1 49  ? -21.02826  -24.42293 -108.80569 1.000 18.44175  ? 49  PHE   A CG  1 
ATOM   365  C CD1 . PHE   A 1 49  ? -19.87481  -24.51622 -108.03956 1.000 20.04391  ? 49  PHE   A CD1 1 
ATOM   366  C CD2 . PHE   A 1 49  ? -21.10373  -25.15953 -109.97874 1.000 17.23013  ? 49  PHE   A CD2 1 
ATOM   367  C CE1 . PHE   A 1 49  ? -18.81736  -25.33740 -108.43397 1.000 16.79715  ? 49  PHE   A CE1 1 
ATOM   368  C CE2 . PHE   A 1 49  ? -20.03992  -25.96941 -110.38772 1.000 20.60083  ? 49  PHE   A CE2 1 
ATOM   369  C CZ  . PHE   A 1 49  ? -18.89987  -26.05731 -109.61543 1.000 13.29947  ? 49  PHE   A CZ  1 
ATOM   370  N N   . GLU   A 1 50  ? -22.03364  -22.21859 -105.53875 1.000 19.08112  ? 50  GLU   A N   1 
ATOM   371  C CA  . GLU   A 1 50  ? -21.19374  -21.71933 -104.45310 1.000 20.60548  ? 50  GLU   A CA  1 
ATOM   372  C C   . GLU   A 1 50  ? -21.57508  -22.31923 -103.10470 1.000 20.00484  ? 50  GLU   A C   1 
ATOM   373  O O   . GLU   A 1 50  ? -20.73897  -22.34788 -102.19647 1.000 16.39425  ? 50  GLU   A O   1 
ATOM   374  C CB  . GLU   A 1 50  ? -21.25619  -20.18727 -104.37258 1.000 18.96768  ? 50  GLU   A CB  1 
ATOM   375  C CG  . GLU   A 1 50  ? -22.63207  -19.64602 -103.97207 1.000 24.71270  ? 50  GLU   A CG  1 
ATOM   376  C CD  . GLU   A 1 50  ? -22.67109  -18.13304 -103.83844 1.000 22.00804  ? 50  GLU   A CD  1 
ATOM   377  O OE1 . GLU   A 1 50  ? -21.72146  -17.46092 -104.30078 1.000 26.47764  ? 50  GLU   A OE1 1 
ATOM   378  O OE2 . GLU   A 1 50  ? -23.65456  -17.61565 -103.26511 1.000 29.31203  ? 50  GLU   A OE2 1 
ATOM   379  N N   . HIS   A 1 51  ? -22.80379  -22.81034 -102.94847 1.000 15.63923  ? 51  HIS   A N   1 
ATOM   380  C CA  . HIS   A 1 51  ? -23.21844  -23.39762 -101.68226 1.000 16.29540  ? 51  HIS   A CA  1 
ATOM   381  C C   . HIS   A 1 51  ? -23.12096  -24.91589 -101.67790 1.000 14.93872  ? 51  HIS   A C   1 
ATOM   382  O O   . HIS   A 1 51  ? -23.41313  -25.54667 -100.65674 1.000 16.39191  ? 51  HIS   A O   1 
ATOM   383  C CB  . HIS   A 1 51  ? -24.64354  -22.94953 -101.33174 1.000 15.54758  ? 51  HIS   A CB  1 
ATOM   384  C CG  . HIS   A 1 51  ? -24.72637  -21.51543 -100.92477 1.000 18.23276  ? 51  HIS   A CG  1 
ATOM   385  N ND1 . HIS   A 1 51  ? -24.14720  -21.03944 -99.76854  1.000 19.69860  ? 51  HIS   A ND1 1 
ATOM   386  C CD2 . HIS   A 1 51  ? -25.29804  -20.44695 -101.52659 1.000 18.65510  ? 51  HIS   A CD2 1 
ATOM   387  C CE1 . HIS   A 1 51  ? -24.36361  -19.73964 -99.67245  1.000 16.86169  ? 51  HIS   A CE1 1 
ATOM   388  N NE2 . HIS   A 1 51  ? -25.05571  -19.35473 -100.72861 1.000 23.07125  ? 51  HIS   A NE2 1 
ATOM   389  N N   . LEU   A 1 52  ? -22.70795  -25.51772 -102.78269 1.000 18.30331  ? 52  LEU   A N   1 
ATOM   390  C CA  . LEU   A 1 52  ? -22.55324  -26.96333 -102.85451 1.000 16.51356  ? 52  LEU   A CA  1 
ATOM   391  C C   . LEU   A 1 52  ? -21.10790  -27.40125 -103.02400 1.000 20.28306  ? 52  LEU   A C   1 
ATOM   392  O O   . LEU   A 1 52  ? -20.68293  -28.34827 -102.35624 1.000 15.85042  ? 52  LEU   A O   1 
ATOM   393  C CB  . LEU   A 1 52  ? -23.39841  -27.52447 -103.99813 1.000 14.24986  ? 52  LEU   A CB  1 
ATOM   394  C CG  . LEU   A 1 52  ? -24.92302  -27.47296 -103.75264 1.000 17.34346  ? 52  LEU   A CG  1 
ATOM   395  C CD1 . LEU   A 1 52  ? -25.66710  -28.20581 -104.84295 1.000 12.90188  ? 52  LEU   A CD1 1 
ATOM   396  C CD2 . LEU   A 1 52  ? -25.28194  -28.07569 -102.40223 1.000 21.51225  ? 52  LEU   A CD2 1 
ATOM   397  N N   . GLN   A 1 53  ? -20.33439  -26.72621 -103.88355 1.000 18.32638  ? 53  GLN   A N   1 
ATOM   398  C CA  . GLN   A 1 53  ? -18.91847  -27.03224 -104.10075 1.000 16.33957  ? 53  GLN   A CA  1 
ATOM   399  C C   . GLN   A 1 53  ? -18.09678  -25.74773 -104.02835 1.000 18.38052  ? 53  GLN   A C   1 
ATOM   400  O O   . GLN   A 1 53  ? -17.57723  -25.26733 -105.04436 1.000 17.07476  ? 53  GLN   A O   1 
ATOM   401  C CB  . GLN   A 1 53  ? -18.70362  -27.74762 -105.43590 1.000 16.47694  ? 53  GLN   A CB  1 
ATOM   402  C CG  . GLN   A 1 53  ? -17.52313  -28.70631 -105.38876 1.000 16.19677  ? 53  GLN   A CG  1 
ATOM   403  C CD  . GLN   A 1 53  ? -17.04881  -29.17857 -106.74873 1.000 20.67537  ? 53  GLN   A CD  1 
ATOM   404  O OE1 . GLN   A 1 53  ? -16.00145  -29.82378 -106.85945 1.000 20.91529  ? 53  GLN   A OE1 1 
ATOM   405  N NE2 . GLN   A 1 53  ? -17.81390  -28.87387 -107.78928 1.000 22.09243  ? 53  GLN   A NE2 1 
ATOM   406  N N   . PRO   A 1 54  ? -17.96189  -25.16113 -102.83149 1.000 16.62955  ? 54  PRO   A N   1 
ATOM   407  C CA  . PRO   A 1 54  ? -17.27980  -23.86118 -102.73126 1.000 13.93440  ? 54  PRO   A CA  1 
ATOM   408  C C   . PRO   A 1 54  ? -15.81323  -23.91500 -103.11278 1.000 22.78649  ? 54  PRO   A C   1 
ATOM   409  O O   . PRO   A 1 54  ? -15.25147  -22.89154 -103.51925 1.000 23.22085  ? 54  PRO   A O   1 
ATOM   410  C CB  . PRO   A 1 54  ? -17.46713  -23.47987 -101.25530 1.000 16.22084  ? 54  PRO   A CB  1 
ATOM   411  C CG  . PRO   A 1 54  ? -17.80453  -24.75218 -100.55491 1.000 15.52268  ? 54  PRO   A CG  1 
ATOM   412  C CD  . PRO   A 1 54  ? -18.53508  -25.58672 -101.54276 1.000 15.68680  ? 54  PRO   A CD  1 
ATOM   413  N N   . GLU   A 1 55  ? -15.17080  -25.07057 -102.96840 1.000 19.27494  ? 55  GLU   A N   1 
ATOM   414  C CA  . GLU   A 1 55  ? -13.83109  -25.31376 -103.48113 1.000 22.45975  ? 55  GLU   A CA  1 
ATOM   415  C C   . GLU   A 1 55  ? -13.86205  -26.64203 -104.22434 1.000 22.28607  ? 55  GLU   A C   1 
ATOM   416  O O   . GLU   A 1 55  ? -14.73774  -27.48015 -103.98574 1.000 26.11829  ? 55  GLU   A O   1 
ATOM   417  C CB  . GLU   A 1 55  ? -12.77781  -25.32793 -102.34596 1.000 22.04786  ? 55  GLU   A CB  1 
ATOM   418  C CG  . GLU   A 1 55  ? -12.83022  -24.09237 -101.41257 1.000 27.20433  ? 55  GLU   A CG  1 
ATOM   419  C CD  . GLU   A 1 55  ? -12.08143  -24.28601 -100.08465 1.000 42.38090  ? 55  GLU   A CD  1 
ATOM   420  O OE1 . GLU   A 1 55  ? -11.31285  -25.26801 -99.96626  1.000 40.52809  ? 55  GLU   A OE1 1 
ATOM   421  O OE2 . GLU   A 1 55  ? -12.26100  -23.45713 -99.15585  1.000 42.17199  ? 55  GLU   A OE2 1 
ATOM   422  N N   . GLU   A 1 56  ? -12.91771  -26.83361 -105.14367 1.000 22.92892  ? 56  GLU   A N   1 
ATOM   423  C CA  . GLU   A 1 56  ? -12.89827  -28.07502 -105.91517 1.000 23.90912  ? 56  GLU   A CA  1 
ATOM   424  C C   . GLU   A 1 56  ? -12.72405  -29.27781 -104.99704 1.000 17.51849  ? 56  GLU   A C   1 
ATOM   425  O O   . GLU   A 1 56  ? -11.74921  -29.35996 -104.24586 1.000 26.47255  ? 56  GLU   A O   1 
ATOM   426  C CB  . GLU   A 1 56  ? -11.78940  -28.05006 -106.95902 1.000 19.11705  ? 56  GLU   A CB  1 
ATOM   427  C CG  . GLU   A 1 56  ? -11.92480  -29.19653 -107.96373 1.000 23.22339  ? 56  GLU   A CG  1 
ATOM   428  C CD  . GLU   A 1 56  ? -11.05304  -29.01387 -109.19832 1.000 30.77144  ? 56  GLU   A CD  1 
ATOM   429  O OE1 . GLU   A 1 56  ? -10.09416  -28.20590 -109.13037 1.000 23.18001  ? 56  GLU   A OE1 1 
ATOM   430  O OE2 . GLU   A 1 56  ? -11.33514  -29.67645 -110.22961 1.000 23.50261  ? 56  GLU   A OE2 1 
ATOM   431  N N   . GLY   A 1 57  ? -13.67412  -30.20782 -105.05943 1.000 19.27880  ? 57  GLY   A N   1 
ATOM   432  C CA  . GLY   A 1 57  ? -13.65742  -31.40621 -104.24769 1.000 17.01872  ? 57  GLY   A CA  1 
ATOM   433  C C   . GLY   A 1 57  ? -14.23281  -31.24349 -102.85920 1.000 20.89473  ? 57  GLY   A C   1 
ATOM   434  O O   . GLY   A 1 57  ? -14.31682  -32.23317 -102.11375 1.000 20.10274  ? 57  GLY   A O   1 
ATOM   435  N N   . LYS   A 1 58  ? -14.62086  -30.03396 -102.48175 1.000 17.30874  ? 58  LYS   A N   1 
ATOM   436  C CA  . LYS   A 1 58  ? -15.24233  -29.77943 -101.19280 1.000 18.96699  ? 58  LYS   A CA  1 
ATOM   437  C C   . LYS   A 1 58  ? -16.73717  -29.59112 -101.43970 1.000 26.11341  ? 58  LYS   A C   1 
ATOM   438  O O   . LYS   A 1 58  ? -17.17646  -28.55513 -101.95561 1.000 20.76907  ? 58  LYS   A O   1 
ATOM   439  C CB  . LYS   A 1 58  ? -14.61568  -28.56656 -100.51616 1.000 22.55974  ? 58  LYS   A CB  1 
ATOM   440  C CG  . LYS   A 1 58  ? -15.14018  -28.32492 -99.10903  1.000 23.25372  ? 58  LYS   A CG  1 
ATOM   441  C CD  . LYS   A 1 58  ? -14.42839  -27.15006 -98.44699  1.000 21.40564  ? 58  LYS   A CD  1 
ATOM   442  C CE  . LYS   A 1 58  ? -14.97493  -26.94446 -97.05369  1.000 27.82319  ? 58  LYS   A CE  1 
ATOM   443  N NZ  . LYS   A 1 58  ? -14.62109  -25.61462 -96.49156  1.000 31.30224  ? 58  LYS   A NZ  1 
ATOM   444  N N   . PHE   A 1 59  ? -17.51935  -30.60245 -101.08829 1.000 14.21014  ? 59  PHE   A N   1 
ATOM   445  C CA  . PHE   A 1 59  ? -18.96278  -30.54014 -101.24515 1.000 17.28629  ? 59  PHE   A CA  1 
ATOM   446  C C   . PHE   A 1 59  ? -19.60960  -30.28169 -99.89012  1.000 18.89360  ? 59  PHE   A C   1 
ATOM   447  O O   . PHE   A 1 59  ? -19.29396  -30.95678 -98.90432  1.000 21.23527  ? 59  PHE   A O   1 
ATOM   448  C CB  . PHE   A 1 59  ? -19.49058  -31.81994 -101.89499 1.000 15.77545  ? 59  PHE   A CB  1 
ATOM   449  C CG  . PHE   A 1 59  ? -19.09737  -31.95094 -103.34655 1.000 18.22680  ? 59  PHE   A CG  1 
ATOM   450  C CD1 . PHE   A 1 59  ? -19.89304  -31.41312 -104.34513 1.000 15.27559  ? 59  PHE   A CD1 1 
ATOM   451  C CD2 . PHE   A 1 59  ? -17.91273  -32.57605 -103.70565 1.000 15.34320  ? 59  PHE   A CD2 1 
ATOM   452  C CE1 . PHE   A 1 59  ? -19.53393  -31.52478 -105.68967 1.000 19.76372  ? 59  PHE   A CE1 1 
ATOM   453  C CE2 . PHE   A 1 59  ? -17.53936  -32.68800 -105.03575 1.000 20.94200  ? 59  PHE   A CE2 1 
ATOM   454  C CZ  . PHE   A 1 59  ? -18.35644  -32.16216 -106.03852 1.000 19.83662  ? 59  PHE   A CZ  1 
ATOM   455  N N   . THR   A 1 60  ? -20.48307  -29.27887 -99.84012  1.000 15.33531  ? 60  THR   A N   1 
ATOM   456  C CA  . THR   A 1 60  ? -21.15459  -28.86775 -98.61191  1.000 17.62052  ? 60  THR   A CA  1 
ATOM   457  C C   . THR   A 1 60  ? -22.65934  -29.05025 -98.79766  1.000 18.94770  ? 60  THR   A C   1 
ATOM   458  O O   . THR   A 1 60  ? -23.37783  -28.10754 -99.13618  1.000 17.04282  ? 60  THR   A O   1 
ATOM   459  C CB  . THR   A 1 60  ? -20.81470  -27.44072 -98.27005  1.000 15.20860  ? 60  THR   A CB  1 
ATOM   460  O OG1 . THR   A 1 60  ? -21.09242  -26.61414 -99.40549  1.000 17.85479  ? 60  THR   A OG1 1 
ATOM   461  C CG2 . THR   A 1 60  ? -19.33389  -27.31516 -97.91919  1.000 14.38938  ? 60  THR   A CG2 1 
ATOM   462  N N   . PHE   A 1 61  ? -23.13537  -30.25859 -98.53804  1.000 18.42429  ? 61  PHE   A N   1 
ATOM   463  C CA  . PHE   A 1 61  ? -24.53284  -30.60058 -98.74668  1.000 16.50606  ? 61  PHE   A CA  1 
ATOM   464  C C   . PHE   A 1 61  ? -25.39198  -30.38049 -97.52250  1.000 17.72193  ? 61  PHE   A C   1 
ATOM   465  O O   . PHE   A 1 61  ? -26.59183  -30.66608 -97.58066  1.000 17.06709  ? 61  PHE   A O   1 
ATOM   466  C CB  . PHE   A 1 61  ? -24.66439  -32.06710 -99.17257  1.000 12.89516  ? 61  PHE   A CB  1 
ATOM   467  C CG  . PHE   A 1 61  ? -24.18105  -32.33568 -100.56392 1.000 19.35557  ? 61  PHE   A CG  1 
ATOM   468  C CD1 . PHE   A 1 61  ? -24.88612  -31.85557 -101.65990 1.000 13.77543  ? 61  PHE   A CD1 1 
ATOM   469  C CD2 . PHE   A 1 61  ? -23.01339  -33.06669 -100.78094 1.000 16.94832  ? 61  PHE   A CD2 1 
ATOM   470  C CE1 . PHE   A 1 61  ? -24.44263  -32.11152 -102.95732 1.000 17.40573  ? 61  PHE   A CE1 1 
ATOM   471  C CE2 . PHE   A 1 61  ? -22.56092  -33.32111 -102.07047 1.000 16.16723  ? 61  PHE   A CE2 1 
ATOM   472  C CZ  . PHE   A 1 61  ? -23.27594  -32.84640 -103.16484 1.000 15.60077  ? 61  PHE   A CZ  1 
ATOM   473  N N   . GLN   A 1 62  ? -24.82015  -29.90466 -96.41510  1.000 15.57130  ? 62  GLN   A N   1 
ATOM   474  C CA  . GLN   A 1 62  ? -25.54369  -29.97084 -95.14744  1.000 19.22559  ? 62  GLN   A CA  1 
ATOM   475  C C   . GLN   A 1 62  ? -26.85930  -29.18375 -95.21139  1.000 21.13407  ? 62  GLN   A C   1 
ATOM   476  O O   . GLN   A 1 62  ? -27.93014  -29.72338 -94.91052  1.000 17.49414  ? 62  GLN   A O   1 
ATOM   477  C CB  . GLN   A 1 62  ? -24.64552  -29.48449 -94.00738  1.000 18.85235  ? 62  GLN   A CB  1 
ATOM   478  C CG  . GLN   A 1 62  ? -23.27626  -30.20862 -93.91604  1.000 17.78464  ? 62  GLN   A CG  1 
ATOM   479  C CD  . GLN   A 1 62  ? -22.13748  -29.39084 -94.52722  1.000 21.24779  ? 62  GLN   A CD  1 
ATOM   480  O OE1 . GLN   A 1 62  ? -22.19265  -28.98990 -95.69938  1.000 16.25025  ? 62  GLN   A OE1 1 
ATOM   481  N NE2 . GLN   A 1 62  ? -21.11331  -29.11398 -93.72374  1.000 21.81703  ? 62  GLN   A NE2 1 
ATOM   482  N N   . GLU   A 1 63  ? -26.80716  -27.92243 -95.65714  1.000 21.31777  ? 63  GLU   A N   1 
ATOM   483  C CA  . GLU   A 1 63  ? -28.01739  -27.09583 -95.69562  1.000 22.10591  ? 63  GLU   A CA  1 
ATOM   484  C C   . GLU   A 1 63  ? -29.02807  -27.61062 -96.71772  1.000 19.09260  ? 63  GLU   A C   1 
ATOM   485  O O   . GLU   A 1 63  ? -30.22721  -27.67889 -96.42741  1.000 23.79544  ? 63  GLU   A O   1 
ATOM   486  C CB  . GLU   A 1 63  ? -27.65075  -25.64432 -95.99139  1.000 20.94433  ? 63  GLU   A CB  1 
ATOM   487  C CG  . GLU   A 1 63  ? -26.45437  -25.15391 -95.18998  1.000 28.73813  ? 63  GLU   A CG  1 
ATOM   488  C CD  . GLU   A 1 63  ? -26.84390  -24.48246 -93.88531  1.000 45.36890  ? 63  GLU   A CD  1 
ATOM   489  O OE1 . GLU   A 1 63  ? -27.64803  -25.07058 -93.11792  1.000 40.68656  ? 63  GLU   A OE1 1 
ATOM   490  O OE2 . GLU   A 1 63  ? -26.33517  -23.35976 -93.63168  1.000 54.30050  ? 63  GLU   A OE2 1 
ATOM   491  N N   . ALA   A 1 64  ? -28.56812  -27.96038 -97.92283  1.000 16.54123  ? 64  ALA   A N   1 
ATOM   492  C CA  . ALA   A 1 64  ? -29.44458  -28.58429 -98.90862  1.000 13.76706  ? 64  ALA   A CA  1 
ATOM   493  C C   . ALA   A 1 64  ? -30.09277  -29.84976 -98.35969  1.000 19.53746  ? 64  ALA   A C   1 
ATOM   494  O O   . ALA   A 1 64  ? -31.27304  -30.11846 -98.63254  1.000 18.50787  ? 64  ALA   A O   1 
ATOM   495  C CB  . ALA   A 1 64  ? -28.65753  -28.91236 -100.17882 1.000 13.20716  ? 64  ALA   A CB  1 
ATOM   496  N N   . ASP   A 1 65  ? -29.32893  -30.64933 -97.60020  1.000 18.30164  ? 65  ASP   A N   1 
ATOM   497  C CA  . ASP   A 1 65  ? -29.86878  -31.87319 -97.00922  1.000 18.41182  ? 65  ASP   A CA  1 
ATOM   498  C C   . ASP   A 1 65  ? -31.02830  -31.57168 -96.06161  1.000 17.31369  ? 65  ASP   A C   1 
ATOM   499  O O   . ASP   A 1 65  ? -32.01492  -32.30873 -96.03215  1.000 20.09634  ? 65  ASP   A O   1 
ATOM   500  C CB  . ASP   A 1 65  ? -28.77993  -32.62737 -96.23894  1.000 19.38786  ? 65  ASP   A CB  1 
ATOM   501  C CG  . ASP   A 1 65  ? -27.79207  -33.37392 -97.13227  1.000 22.68089  ? 65  ASP   A CG  1 
ATOM   502  O OD1 . ASP   A 1 65  ? -28.04761  -33.63424 -98.33970  1.000 19.20093  ? 65  ASP   A OD1 1 
ATOM   503  O OD2 . ASP   A 1 65  ? -26.73330  -33.72888 -96.57519  1.000 23.70795  ? 65  ASP   A OD2 1 
ATOM   504  N N   . ARG   A 1 66  ? -30.90505  -30.52013 -95.23906  1.000 17.04361  ? 66  ARG   A N   1 
ATOM   505  C CA  . ARG   A 1 66  ? -31.97102  -30.20279 -94.29453  1.000 18.77786  ? 66  ARG   A CA  1 
ATOM   506  C C   . ARG   A 1 66  ? -33.23704  -29.78208 -95.02236  1.000 22.82309  ? 66  ARG   A C   1 
ATOM   507  O O   . ARG   A 1 66  ? -34.34255  -30.20884 -94.66467  1.000 19.73335  ? 66  ARG   A O   1 
ATOM   508  C CB  . ARG   A 1 66  ? -31.51298  -29.12338 -93.30683  1.000 18.58973  ? 66  ARG   A CB  1 
ATOM   509  C CG  . ARG   A 1 66  ? -30.14628  -29.42862 -92.66536  1.000 32.41473  ? 66  ARG   A CG  1 
ATOM   510  C CD  . ARG   A 1 66  ? -29.71032  -28.43849 -91.54407  1.000 27.11780  ? 66  ARG   A CD  1 
ATOM   511  N NE  . ARG   A 1 66  ? -28.45235  -27.73534 -91.83476  1.000 51.07981  ? 66  ARG   A NE  1 
ATOM   512  C CZ  . ARG   A 1 66  ? -27.23838  -28.07999 -91.37434  1.000 55.21223  ? 66  ARG   A CZ  1 
ATOM   513  N NH1 . ARG   A 1 66  ? -27.07077  -29.14524 -90.59080  1.000 50.40539  ? 66  ARG   A NH1 1 
ATOM   514  N NH2 . ARG   A 1 66  ? -26.17273  -27.35249 -91.70650  1.000 32.52976  ? 66  ARG   A NH2 1 
ATOM   515  N N   . ILE   A 1 67  ? -33.07982  -28.97600 -96.06874  1.000 24.49516  ? 67  ILE   A N   1 
ATOM   516  C CA  . ILE   A 1 67  ? -34.19671  -28.60762 -96.92637  1.000 20.24148  ? 67  ILE   A CA  1 
ATOM   517  C C   . ILE   A 1 67  ? -34.87153  -29.84964 -97.50054  1.000 24.46323  ? 67  ILE   A C   1 
ATOM   518  O O   . ILE   A 1 67  ? -36.10375  -29.98218 -97.45836  1.000 21.62799  ? 67  ILE   A O   1 
ATOM   519  C CB  . ILE   A 1 67  ? -33.69626  -27.66812 -98.03154  1.000 16.89365  ? 67  ILE   A CB  1 
ATOM   520  C CG1 . ILE   A 1 67  ? -33.17546  -26.37220 -97.40374  1.000 17.19801  ? 67  ILE   A CG1 1 
ATOM   521  C CG2 . ILE   A 1 67  ? -34.76599  -27.43129 -99.07926  1.000 15.29167  ? 67  ILE   A CG2 1 
ATOM   522  C CD1 . ILE   A 1 67  ? -32.57082  -25.41442 -98.39885  1.000 18.84241  ? 67  ILE   A CD1 1 
ATOM   523  N N   . VAL   A 1 68  ? -34.07655  -30.77737 -98.04963  1.000 18.94619  ? 68  VAL   A N   1 
ATOM   524  C CA  . VAL   A 1 68  ? -34.65396  -31.98862 -98.63747  1.000 20.07645  ? 68  VAL   A CA  1 
ATOM   525  C C   . VAL   A 1 68  ? -35.31234  -32.84045 -97.56396  1.000 19.88639  ? 68  VAL   A C   1 
ATOM   526  O O   . VAL   A 1 68  ? -36.39809  -33.38988 -97.77430  1.000 22.19553  ? 68  VAL   A O   1 
ATOM   527  C CB  . VAL   A 1 68  ? -33.59133  -32.79420 -99.41611  1.000 19.49900  ? 68  VAL   A CB  1 
ATOM   528  C CG1 . VAL   A 1 68  ? -34.15934  -34.12393 -99.90947  1.000 13.85628  ? 68  VAL   A CG1 1 
ATOM   529  C CG2 . VAL   A 1 68  ? -33.08962  -32.00492 -100.59012 1.000 17.82877  ? 68  VAL   A CG2 1 
ATOM   530  N N   . ASP   A 1 69  ? -34.68165  -32.95286 -96.39168  1.000 19.73026  ? 69  ASP   A N   1 
ATOM   531  C CA  . ASP   A 1 69  ? -35.27069  -33.75680 -95.32517  1.000 24.28574  ? 69  ASP   A CA  1 
ATOM   532  C C   . ASP   A 1 69  ? -36.61333  -33.18813 -94.89445  1.000 24.53528  ? 69  ASP   A C   1 
ATOM   533  O O   . ASP   A 1 69  ? -37.59071  -33.93182 -94.72623  1.000 22.45408  ? 69  ASP   A O   1 
ATOM   534  C CB  . ASP   A 1 69  ? -34.32160  -33.83934 -94.13263  1.000 21.60307  ? 69  ASP   A CB  1 
ATOM   535  C CG  . ASP   A 1 69  ? -33.12249  -34.73782 -94.39801  1.000 29.95325  ? 69  ASP   A CG  1 
ATOM   536  O OD1 . ASP   A 1 69  ? -33.21060  -35.62956 -95.27590  1.000 39.07606  ? 69  ASP   A OD1 1 
ATOM   537  O OD2 . ASP   A 1 69  ? -32.08527  -34.54788 -93.72314  1.000 42.35136  ? 69  ASP   A OD2 1 
ATOM   538  N N   . PHE   A 1 70  ? -36.67320  -31.86890 -94.70509  1.000 19.12798  ? 70  PHE   A N   1 
ATOM   539  C CA  . PHE   A 1 70  ? -37.93602  -31.21136 -94.40829  1.000 18.41597  ? 70  PHE   A CA  1 
ATOM   540  C C   . PHE   A 1 70  ? -38.98284  -31.56363 -95.46102  1.000 24.00741  ? 70  PHE   A C   1 
ATOM   541  O O   . PHE   A 1 70  ? -40.08076  -32.03200 -95.12832  1.000 20.79490  ? 70  PHE   A O   1 
ATOM   542  C CB  . PHE   A 1 70  ? -37.72424  -29.69415 -94.31256  1.000 19.82289  ? 70  PHE   A CB  1 
ATOM   543  C CG  . PHE   A 1 70  ? -38.99206  -28.92565 -94.10022  1.000 24.72261  ? 70  PHE   A CG  1 
ATOM   544  C CD1 . PHE   A 1 70  ? -39.51223  -28.76698 -92.82480  1.000 26.32110  ? 70  PHE   A CD1 1 
ATOM   545  C CD2 . PHE   A 1 70  ? -39.68532  -28.38673 -95.17751  1.000 19.83051  ? 70  PHE   A CD2 1 
ATOM   546  C CE1 . PHE   A 1 70  ? -40.69737  -28.06640 -92.61899  1.000 28.24881  ? 70  PHE   A CE1 1 
ATOM   547  C CE2 . PHE   A 1 70  ? -40.87662  -27.70035 -94.99152  1.000 21.49908  ? 70  PHE   A CE2 1 
ATOM   548  C CZ  . PHE   A 1 70  ? -41.38461  -27.53316 -93.71034  1.000 26.23474  ? 70  PHE   A CZ  1 
ATOM   549  N N   . ALA   A 1 71  ? -38.63555  -31.40663 -96.74701  1.000 18.68841  ? 71  ALA   A N   1 
ATOM   550  C CA  . ALA   A 1 71  ? -39.62278  -31.64662 -97.79922  1.000 24.75989  ? 71  ALA   A CA  1 
ATOM   551  C C   . ALA   A 1 71  ? -40.12926  -33.08237 -97.77944  1.000 24.00239  ? 71  ALA   A C   1 
ATOM   552  O O   . ALA   A 1 71  ? -41.33655  -33.32201 -97.88892  1.000 26.33631  ? 71  ALA   A O   1 
ATOM   553  C CB  . ALA   A 1 71  ? -39.04472  -31.31465 -99.16807  1.000 13.09114  ? 71  ALA   A CB  1 
ATOM   554  N N   . CYS   A 1 72  ? -39.22400  -34.04875 -97.64748  1.000 23.78148  ? 72  CYS   A N   1 
ATOM   555  C CA  . CYS   A 1 72  ? -39.62849  -35.45104 -97.63803  1.000 22.47951  ? 72  CYS   A CA  1 
ATOM   556  C C   . CYS   A 1 72  ? -40.45140  -35.79038 -96.40289  1.000 25.46772  ? 72  CYS   A C   1 
ATOM   557  O O   . CYS   A 1 72  ? -41.43033  -36.53677 -96.48956  1.000 29.94506  ? 72  CYS   A O   1 
ATOM   558  C CB  . CYS   A 1 72  ? -38.39397  -36.34474 -97.72275  1.000 23.95369  ? 72  CYS   A CB  1 
ATOM   559  S SG  . CYS   A 1 72  ? -37.51959  -36.21425 -99.31656  1.000 36.00685  ? 72  CYS   A SG  1 
ATOM   560  N N   . SER   A 1 73  ? -40.08292  -35.25186 -95.24468  1.000 25.73756  ? 73  SER   A N   1 
ATOM   561  C CA  . SER   A 1 73  ? -40.85118  -35.57215 -94.05141  1.000 20.96570  ? 73  SER   A CA  1 
ATOM   562  C C   . SER   A 1 73  ? -42.23391  -34.91626 -94.04844  1.000 30.15981  ? 73  SER   A C   1 
ATOM   563  O O   . SER   A 1 73  ? -43.03651  -35.20787 -93.16014  1.000 26.03551  ? 73  SER   A O   1 
ATOM   564  C CB  . SER   A 1 73  ? -40.06143  -35.17932 -92.80277  1.000 15.73369  ? 73  SER   A CB  1 
ATOM   565  O OG  . SER   A 1 73  ? -40.10610  -33.78163 -92.57354  1.000 37.87949  ? 73  SER   A OG  1 
ATOM   566  N N   . HIS   A 1 74  ? -42.54692  -34.06355 -95.02441  1.000 25.53410  ? 74  HIS   A N   1 
ATOM   567  C CA  . HIS   A 1 74  ? -43.88132  -33.48547 -95.13482  1.000 28.35320  ? 74  HIS   A CA  1 
ATOM   568  C C   . HIS   A 1 74  ? -44.49857  -33.73973 -96.50202  1.000 24.59090  ? 74  HIS   A C   1 
ATOM   569  O O   . HIS   A 1 74  ? -45.43413  -33.04324 -96.89068  1.000 26.13220  ? 74  HIS   A O   1 
ATOM   570  C CB  . HIS   A 1 74  ? -43.85644  -31.98876 -94.82305  1.000 21.90528  ? 74  HIS   A CB  1 
ATOM   571  C CG  . HIS   A 1 74  ? -43.51557  -31.68982 -93.39834  1.000 24.72687  ? 74  HIS   A CG  1 
ATOM   572  N ND1 . HIS   A 1 74  ? -42.22944  -31.42468 -92.97872  1.000 37.25773  ? 74  HIS   A ND1 1 
ATOM   573  C CD2 . HIS   A 1 74  ? -44.28652  -31.65111 -92.28757  1.000 26.66162  ? 74  HIS   A CD2 1 
ATOM   574  C CE1 . HIS   A 1 74  ? -42.22370  -31.21857 -91.67336  1.000 27.66828  ? 74  HIS   A CE1 1 
ATOM   575  N NE2 . HIS   A 1 74  ? -43.46014  -31.35046 -91.22957  1.000 37.96821  ? 74  HIS   A NE2 1 
ATOM   576  N N   . ARG   A 1 75  ? -43.99087  -34.73317 -97.23002  1.000 28.12639  ? 75  ARG   A N   1 
ATOM   577  C CA  . ARG   A 1 75  ? -44.54749  -35.14893 -98.51794  1.000 28.32185  ? 75  ARG   A CA  1 
ATOM   578  C C   . ARG   A 1 75  ? -44.60657  -33.97977 -99.50354  1.000 26.94252  ? 75  ARG   A C   1 
ATOM   579  O O   . ARG   A 1 75  ? -45.61066  -33.75494 -100.18155 1.000 24.15624  ? 75  ARG   A O   1 
ATOM   580  C CB  . ARG   A 1 75  ? -45.93082  -35.78621 -98.33487  1.000 40.85328  ? 75  ARG   A CB  1 
ATOM   581  C CG  . ARG   A 1 75  ? -45.98163  -36.98283 -97.37436  1.000 52.15995  ? 75  ARG   A CG  1 
ATOM   582  C CD  . ARG   A 1 75  ? -47.26574  -36.98506 -96.50154  1.000 65.03571  ? 75  ARG   A CD  1 
ATOM   583  N NE  . ARG   A 1 75  ? -47.39297  -35.77420 -95.67547  1.000 85.46396  ? 75  ARG   A NE  1 
ATOM   584  C CZ  . ARG   A 1 75  ? -47.07022  -35.68290 -94.38032  1.000 81.18118  ? 75  ARG   A CZ  1 
ATOM   585  N NH1 . ARG   A 1 75  ? -46.59515  -36.73948 -93.71762  1.000 65.48423  ? 75  ARG   A NH1 1 
ATOM   586  N NH2 . ARG   A 1 75  ? -47.21993  -34.52218 -93.74176  1.000 73.79429  ? 75  ARG   A NH2 1 
ATOM   587  N N   . MET   A 1 76  ? -43.52442  -33.21501 -99.57282  1.000 19.76227  ? 76  MET   A N   1 
ATOM   588  C CA  . MET   A 1 76  ? -43.43167  -32.12486 -100.52779 1.000 20.96022  ? 76  MET   A CA  1 
ATOM   589  C C   . MET   A 1 76  ? -42.44558  -32.49734 -101.61845 1.000 21.53532  ? 76  MET   A C   1 
ATOM   590  O O   . MET   A 1 76  ? -41.39569  -33.08241 -101.33862 1.000 26.64301  ? 76  MET   A O   1 
ATOM   591  C CB  . MET   A 1 76  ? -43.00562  -30.82907 -99.85010  1.000 17.79882  ? 76  MET   A CB  1 
ATOM   592  C CG  . MET   A 1 76  ? -44.02632  -30.30690 -98.86452  1.000 14.83434  ? 76  MET   A CG  1 
ATOM   593  S SD  . MET   A 1 76  ? -43.24502  -29.29804 -97.60340  1.000 19.16355  ? 76  MET   A SD  1 
ATOM   594  C CE  . MET   A 1 76  ? -44.63828  -28.83785 -96.56263  1.000 23.49736  ? 76  MET   A CE  1 
ATOM   595  N N   . ALA   A 1 77  ? -42.79398  -32.18263 -102.86256 1.000 17.75069  ? 77  ALA   A N   1 
ATOM   596  C CA  . ALA   A 1 77  ? -41.83161  -32.34066 -103.94223 1.000 16.91074  ? 77  ALA   A CA  1 
ATOM   597  C C   . ALA   A 1 77  ? -40.70427  -31.32183 -103.78627 1.000 14.40282  ? 77  ALA   A C   1 
ATOM   598  O O   . ALA   A 1 77  ? -40.81414  -30.35275 -103.03049 1.000 15.35915  ? 77  ALA   A O   1 
ATOM   599  C CB  . ALA   A 1 77  ? -42.51633  -32.19051 -105.30015 1.000 14.50647  ? 77  ALA   A CB  1 
ATOM   600  N N   . VAL   A 1 78  ? -39.59850  -31.54968 -104.49836 1.000 15.54811  ? 78  VAL   A N   1 
ATOM   601  C CA  . VAL   A 1 78  ? -38.45624  -30.64023 -104.45624 1.000 14.30618  ? 78  VAL   A CA  1 
ATOM   602  C C   . VAL   A 1 78  ? -38.00139  -30.31220 -105.87191 1.000 22.35004  ? 78  VAL   A C   1 
ATOM   603  O O   . VAL   A 1 78  ? -37.77550  -31.22075 -106.68078 1.000 16.46031  ? 78  VAL   A O   1 
ATOM   604  C CB  . VAL   A 1 78  ? -37.27954  -31.22894 -103.66443 1.000 17.54863  ? 78  VAL   A CB  1 
ATOM   605  C CG1 . VAL   A 1 78  ? -36.08094  -30.25423 -103.68829 1.000 14.20475  ? 78  VAL   A CG1 1 
ATOM   606  C CG2 . VAL   A 1 78  ? -37.70722  -31.54409 -102.26202 1.000 18.58874  ? 78  VAL   A CG2 1 
ATOM   607  N N   . ARG   A 1 79  ? -37.84358  -29.01692 -106.16065 1.000 14.28373  ? 79  ARG   A N   1 
ATOM   608  C CA  . ARG   A 1 79  ? -37.19333  -28.56636 -107.38016 1.000 15.43362  ? 79  ARG   A CA  1 
ATOM   609  C C   . ARG   A 1 79  ? -35.75465  -28.21831 -107.04462 1.000 14.35269  ? 79  ARG   A C   1 
ATOM   610  O O   . ARG   A 1 79  ? -35.49633  -27.48051 -106.08411 1.000 10.90513  ? 79  ARG   A O   1 
ATOM   611  C CB  . ARG   A 1 79  ? -37.89299  -27.35083 -107.99935 1.000 16.77881  ? 79  ARG   A CB  1 
ATOM   612  C CG  . ARG   A 1 79  ? -39.40100  -27.47991 -108.23027 1.000 14.79809  ? 79  ARG   A CG  1 
ATOM   613  C CD  . ARG   A 1 79  ? -39.94583  -26.23833 -108.97870 1.000 13.32923  ? 79  ARG   A CD  1 
ATOM   614  N NE  . ARG   A 1 79  ? -39.59112  -26.30013 -110.39538 1.000 13.44870  ? 79  ARG   A NE  1 
ATOM   615  C CZ  . ARG   A 1 79  ? -38.54883  -25.67987 -110.93542 1.000 11.84801  ? 79  ARG   A CZ  1 
ATOM   616  N NH1 . ARG   A 1 79  ? -37.76653  -24.91677 -110.18832 1.000 13.34582  ? 79  ARG   A NH1 1 
ATOM   617  N NH2 . ARG   A 1 79  ? -38.28648  -25.83048 -112.22340 1.000 14.57515  ? 79  ARG   A NH2 1 
ATOM   618  N N   . GLY   A 1 80  ? -34.82300  -28.74397 -107.83831 1.000 14.71743  ? 80  GLY   A N   1 
ATOM   619  C CA  . GLY   A 1 80  ? -33.41550  -28.44219 -107.65546 1.000 11.60824  ? 80  GLY   A CA  1 
ATOM   620  C C   . GLY   A 1 80  ? -33.07580  -27.16975 -108.39556 1.000 11.10925  ? 80  GLY   A C   1 
ATOM   621  O O   . GLY   A 1 80  ? -33.41476  -27.01790 -109.57024 1.000 15.93067  ? 80  GLY   A O   1 
ATOM   622  N N   . HIS   A 1 81  ? -32.40865  -26.25198 -107.70314 1.000 13.26160  ? 81  HIS   A N   1 
ATOM   623  C CA  . HIS   A 1 81  ? -32.05560  -24.95125 -108.26720 1.000 16.95874  ? 81  HIS   A CA  1 
ATOM   624  C C   . HIS   A 1 81  ? -30.69327  -24.54301 -107.71514 1.000 13.46076  ? 81  HIS   A C   1 
ATOM   625  O O   . HIS   A 1 81  ? -30.55294  -24.39173 -106.49777 1.000 16.24249  ? 81  HIS   A O   1 
ATOM   626  C CB  . HIS   A 1 81  ? -33.13829  -23.91799 -107.91036 1.000 6.30581   ? 81  HIS   A CB  1 
ATOM   627  C CG  . HIS   A 1 81  ? -32.84628  -22.53367 -108.38707 1.000 13.60221  ? 81  HIS   A CG  1 
ATOM   628  N ND1 . HIS   A 1 81  ? -33.15189  -22.10308 -109.66187 1.000 18.92300  ? 81  HIS   A ND1 1 
ATOM   629  C CD2 . HIS   A 1 81  ? -32.28410  -21.47207 -107.75814 1.000 19.64026  ? 81  HIS   A CD2 1 
ATOM   630  C CE1 . HIS   A 1 81  ? -32.78855  -20.83928 -109.79956 1.000 11.74685  ? 81  HIS   A CE1 1 
ATOM   631  N NE2 . HIS   A 1 81  ? -32.25512  -20.43392 -108.65953 1.000 17.63357  ? 81  HIS   A NE2 1 
ATOM   632  N N   . THR   A 1 82  ? -29.67974  -24.36908 -108.56878 1.000 13.73446  ? 82  THR   A N   1 
ATOM   633  C CA  . THR   A 1 82  ? -29.67904  -24.52341 -110.02285 1.000 13.79620  ? 82  THR   A CA  1 
ATOM   634  C C   . THR   A 1 82  ? -28.24949  -24.95045 -110.37022 1.000 13.41394  ? 82  THR   A C   1 
ATOM   635  O O   . THR   A 1 82  ? -27.33193  -24.62233 -109.62302 1.000 18.10619  ? 82  THR   A O   1 
ATOM   636  C CB  . THR   A 1 82  ? -30.05266  -23.19061 -110.75454 1.000 12.86682  ? 82  THR   A CB  1 
ATOM   637  O OG1 . THR   A 1 82  ? -29.84924  -23.33368 -112.15873 1.000 16.52315  ? 82  THR   A OG1 1 
ATOM   638  C CG2 . THR   A 1 82  ? -29.17980  -22.03502 -110.26400 1.000 13.16643  ? 82  THR   A CG2 1 
ATOM   639  N N   . LEU   A 1 83  ? -28.02710  -25.64627 -111.48787 1.000 14.45371  ? 83  LEU   A N   1 
ATOM   640  C CA  . LEU   A 1 83  ? -26.69911  -26.20848 -111.75166 1.000 13.23863  ? 83  LEU   A CA  1 
ATOM   641  C C   . LEU   A 1 83  ? -25.74396  -25.22204 -112.42581 1.000 19.65106  ? 83  LEU   A C   1 
ATOM   642  O O   . LEU   A 1 83  ? -24.63145  -24.99285 -111.93454 1.000 14.81762  ? 83  LEU   A O   1 
ATOM   643  C CB  . LEU   A 1 83  ? -26.81395  -27.47635 -112.60059 1.000 14.02605  ? 83  LEU   A CB  1 
ATOM   644  C CG  . LEU   A 1 83  ? -27.64978  -28.55370 -111.92181 1.000 17.09989  ? 83  LEU   A CG  1 
ATOM   645  C CD1 . LEU   A 1 83  ? -27.91333  -29.74025 -112.86057 1.000 15.89453  ? 83  LEU   A CD1 1 
ATOM   646  C CD2 . LEU   A 1 83  ? -26.95643  -28.98375 -110.66388 1.000 9.74470   ? 83  LEU   A CD2 1 
ATOM   647  N N   . VAL   A 1 84  ? -26.14183  -24.65053 -113.55882 1.000 14.64741  ? 84  VAL   A N   1 
ATOM   648  C CA  . VAL   A 1 84  ? -25.23940  -23.83150 -114.36259 1.000 14.88440  ? 84  VAL   A CA  1 
ATOM   649  C C   . VAL   A 1 84  ? -25.82983  -22.43052 -114.50495 1.000 19.39032  ? 84  VAL   A C   1 
ATOM   650  O O   . VAL   A 1 84  ? -26.93257  -22.26106 -115.04297 1.000 17.49290  ? 84  VAL   A O   1 
ATOM   651  C CB  . VAL   A 1 84  ? -24.97299  -24.47318 -115.73264 1.000 19.85380  ? 84  VAL   A CB  1 
ATOM   652  C CG1 . VAL   A 1 84  ? -24.06102  -23.58369 -116.58698 1.000 12.29806  ? 84  VAL   A CG1 1 
ATOM   653  C CG2 . VAL   A 1 84  ? -24.35207  -25.85254 -115.53864 1.000 15.15578  ? 84  VAL   A CG2 1 
ATOM   654  N N   . TRP   A 1 85  ? -25.07894  -21.42808 -114.05284 1.000 18.27462  ? 85  TRP   A N   1 
ATOM   655  C CA  . TRP   A 1 85  ? -25.57077  -20.06319 -113.93009 1.000 21.71181  ? 85  TRP   A CA  1 
ATOM   656  C C   . TRP   A 1 85  ? -24.37099  -19.13207 -113.91284 1.000 25.03266  ? 85  TRP   A C   1 
ATOM   657  O O   . TRP   A 1 85  ? -23.31868  -19.48457 -113.37604 1.000 24.89141  ? 85  TRP   A O   1 
ATOM   658  C CB  . TRP   A 1 85  ? -26.38923  -19.88924 -112.63941 1.000 21.46236  ? 85  TRP   A CB  1 
ATOM   659  C CG  . TRP   A 1 85  ? -27.17777  -18.60213 -112.51574 1.000 22.84281  ? 85  TRP   A CG  1 
ATOM   660  C CD1 . TRP   A 1 85  ? -27.62399  -17.79373 -113.53499 1.000 20.36216  ? 85  TRP   A CD1 1 
ATOM   661  C CD2 . TRP   A 1 85  ? -27.63497  -17.99291 -111.29353 1.000 24.88544  ? 85  TRP   A CD2 1 
ATOM   662  N NE1 . TRP   A 1 85  ? -28.32517  -16.72090 -113.01461 1.000 20.63725  ? 85  TRP   A NE1 1 
ATOM   663  C CE2 . TRP   A 1 85  ? -28.34230  -16.81816 -111.64584 1.000 20.36200  ? 85  TRP   A CE2 1 
ATOM   664  C CE3 . TRP   A 1 85  ? -27.51177  -18.32412 -109.94022 1.000 16.50319  ? 85  TRP   A CE3 1 
ATOM   665  C CZ2 . TRP   A 1 85  ? -28.92480  -15.98235 -110.69054 1.000 22.65876  ? 85  TRP   A CZ2 1 
ATOM   666  C CZ3 . TRP   A 1 85  ? -28.09824  -17.49240 -108.99406 1.000 19.68624  ? 85  TRP   A CZ3 1 
ATOM   667  C CH2 . TRP   A 1 85  ? -28.79962  -16.33828 -109.37483 1.000 18.84942  ? 85  TRP   A CH2 1 
ATOM   668  N N   . HIS   A 1 86  ? -24.54562  -17.93037 -114.47441 1.000 23.06044  ? 86  HIS   A N   1 
ATOM   669  C CA  . HIS   A 1 86  ? -23.48265  -16.92648 -114.42310 1.000 21.37796  ? 86  HIS   A CA  1 
ATOM   670  C C   . HIS   A 1 86  ? -23.33129  -16.29548 -113.04721 1.000 26.71192  ? 86  HIS   A C   1 
ATOM   671  O O   . HIS   A 1 86  ? -22.34487  -15.58818 -112.81957 1.000 25.20998  ? 86  HIS   A O   1 
ATOM   672  C CB  . HIS   A 1 86  ? -23.70943  -15.82168 -115.47264 1.000 21.32064  ? 86  HIS   A CB  1 
ATOM   673  C CG  . HIS   A 1 86  ? -24.96586  -15.02977 -115.26614 1.000 25.15017  ? 86  HIS   A CG  1 
ATOM   674  N ND1 . HIS   A 1 86  ? -26.20242  -15.46921 -115.69149 1.000 21.29396  ? 86  HIS   A ND1 1 
ATOM   675  C CD2 . HIS   A 1 86  ? -25.17588  -13.82565 -114.68370 1.000 24.50325  ? 86  HIS   A CD2 1 
ATOM   676  C CE1 . HIS   A 1 86  ? -27.12120  -14.57357 -115.37216 1.000 23.94121  ? 86  HIS   A CE1 1 
ATOM   677  N NE2 . HIS   A 1 86  ? -26.52502  -13.56591 -114.76066 1.000 28.04843  ? 86  HIS   A NE2 1 
ATOM   678  N N   . ASN   A 1 87  ? -24.25769  -16.52576 -112.12345 1.000 23.15698  ? 87  ASN   A N   1 
ATOM   679  C CA  . ASN   A 1 87  ? -24.10466  -15.97272 -110.78647 1.000 25.83516  ? 87  ASN   A CA  1 
ATOM   680  C C   . ASN   A 1 87  ? -23.80174  -17.07170 -109.77616 1.000 24.13228  ? 87  ASN   A C   1 
ATOM   681  O O   . ASN   A 1 87  ? -23.95915  -18.26498 -110.04405 1.000 18.82811  ? 87  ASN   A O   1 
ATOM   682  C CB  . ASN   A 1 87  ? -25.35418  -15.18927 -110.37062 1.000 23.78287  ? 87  ASN   A CB  1 
ATOM   683  C CG  . ASN   A 1 87  ? -25.40846  -13.82303 -111.01371 1.000 23.73201  ? 87  ASN   A CG  1 
ATOM   684  O OD1 . ASN   A 1 87  ? -24.37792  -13.27220 -111.39323 1.000 29.50981  ? 87  ASN   A OD1 1 
ATOM   685  N ND2 . ASN   A 1 87  ? -26.60943  -13.27515 -111.15707 1.000 31.40457  ? 87  ASN   A ND2 1 
ATOM   686  N N   . GLN   A 1 88  ? -23.34166  -16.63779 -108.60324 1.000 23.99837  ? 88  GLN   A N   1 
ATOM   687  C CA  . GLN   A 1 88  ? -23.17283  -17.51744 -107.44679 1.000 27.38317  ? 88  GLN   A CA  1 
ATOM   688  C C   . GLN   A 1 88  ? -22.43542  -18.80603 -107.82279 1.000 21.85008  ? 88  GLN   A C   1 
ATOM   689  O O   . GLN   A 1 88  ? -22.80162  -19.91366 -107.42208 1.000 22.76893  ? 88  GLN   A O   1 
ATOM   690  C CB  . GLN   A 1 88  ? -24.53044  -17.78914 -106.78700 1.000 16.62793  ? 88  GLN   A CB  1 
ATOM   691  C CG  . GLN   A 1 88  ? -25.16720  -16.49515 -106.29159 1.000 21.43140  ? 88  GLN   A CG  1 
ATOM   692  C CD  . GLN   A 1 88  ? -26.46710  -16.68688 -105.54293 1.000 19.43936  ? 88  GLN   A CD  1 
ATOM   693  O OE1 . GLN   A 1 88  ? -27.54280  -16.37525 -106.05987 1.000 24.42513  ? 88  GLN   A OE1 1 
ATOM   694  N NE2 . GLN   A 1 88  ? -26.38124  -17.19261 -104.31784 1.000 20.46936  ? 88  GLN   A NE2 1 
ATOM   695  N N   . THR   A 1 89  ? -21.38271  -18.65136 -108.61552 1.000 26.34166  ? 89  THR   A N   1 
ATOM   696  C CA  . THR   A 1 89  ? -20.49039  -19.74071 -108.97116 1.000 25.60252  ? 89  THR   A CA  1 
ATOM   697  C C   . THR   A 1 89  ? -19.07308  -19.30349 -108.62597 1.000 25.25523  ? 89  THR   A C   1 
ATOM   698  O O   . THR   A 1 89  ? -18.62478  -18.24040 -109.09304 1.000 33.27429  ? 89  THR   A O   1 
ATOM   699  C CB  . THR   A 1 89  ? -20.61407  -20.07859 -110.45772 1.000 21.70991  ? 89  THR   A CB  1 
ATOM   700  O OG1 . THR   A 1 89  ? -21.92602  -20.58986 -110.70643 1.000 22.05429  ? 89  THR   A OG1 1 
ATOM   701  C CG2 . THR   A 1 89  ? -19.58714  -21.12646 -110.86477 1.000 22.89229  ? 89  THR   A CG2 1 
ATOM   702  N N   . PRO   A 1 90  ? -18.34348  -20.06842 -107.81910 1.000 29.60877  ? 90  PRO   A N   1 
ATOM   703  C CA  . PRO   A 1 90  ? -17.03117  -19.60522 -107.34692 1.000 27.68930  ? 90  PRO   A CA  1 
ATOM   704  C C   . PRO   A 1 90  ? -16.03247  -19.48336 -108.48638 1.000 26.70575  ? 90  PRO   A C   1 
ATOM   705  O O   . PRO   A 1 90  ? -16.17533  -20.09398 -109.54757 1.000 25.12447  ? 90  PRO   A O   1 
ATOM   706  C CB  . PRO   A 1 90  ? -16.59857  -20.68445 -106.34621 1.000 27.71572  ? 90  PRO   A CB  1 
ATOM   707  C CG  . PRO   A 1 90  ? -17.84708  -21.47930 -106.04572 1.000 25.52926  ? 90  PRO   A CG  1 
ATOM   708  C CD  . PRO   A 1 90  ? -18.68671  -21.39617 -107.29214 1.000 27.89717  ? 90  PRO   A CD  1 
ATOM   709  N N   . ASP   A 1 91  ? -14.99527  -18.67512 -108.24047 1.000 27.11272  ? 91  ASP   A N   1 
ATOM   710  C CA  . ASP   A 1 91  ? -14.02146  -18.38283 -109.28643 1.000 29.27152  ? 91  ASP   A CA  1 
ATOM   711  C C   . ASP   A 1 91  ? -13.20026  -19.60774 -109.66568 1.000 25.06566  ? 91  ASP   A C   1 
ATOM   712  O O   . ASP   A 1 91  ? -12.79949  -19.74145 -110.83144 1.000 27.54315  ? 91  ASP   A O   1 
ATOM   713  C CB  . ASP   A 1 91  ? -13.09435  -17.24739 -108.84338 1.000 36.10713  ? 91  ASP   A CB  1 
ATOM   714  C CG  . ASP   A 1 91  ? -13.77323  -15.87335 -108.88312 1.000 40.47245  ? 91  ASP   A CG  1 
ATOM   715  O OD1 . ASP   A 1 91  ? -14.65911  -15.64340 -109.73767 1.000 40.56976  ? 91  ASP   A OD1 1 
ATOM   716  O OD2 . ASP   A 1 91  ? -13.41895  -15.01832 -108.04604 1.000 40.37332  ? 91  ASP   A OD2 1 
ATOM   717  N N   . TRP   A 1 92  ? -12.94704  -20.51314 -108.71150 1.000 21.21669  ? 92  TRP   A N   1 
ATOM   718  C CA  . TRP   A 1 92  ? -12.07042  -21.64833 -108.99581 1.000 26.11061  ? 92  TRP   A CA  1 
ATOM   719  C C   . TRP   A 1 92  ? -12.55772  -22.44176 -110.19732 1.000 26.31125  ? 92  TRP   A C   1 
ATOM   720  O O   . TRP   A 1 92  ? -11.74617  -23.02925 -110.91883 1.000 29.38667  ? 92  TRP   A O   1 
ATOM   721  C CB  . TRP   A 1 92  ? -11.93961  -22.56238 -107.76846 1.000 24.61431  ? 92  TRP   A CB  1 
ATOM   722  C CG  . TRP   A 1 92  ? -13.15392  -23.44633 -107.44229 1.000 22.36490  ? 92  TRP   A CG  1 
ATOM   723  C CD1 . TRP   A 1 92  ? -14.05646  -23.24153 -106.44210 1.000 21.70738  ? 92  TRP   A CD1 1 
ATOM   724  C CD2 . TRP   A 1 92  ? -13.55278  -24.67212 -108.09149 1.000 18.06497  ? 92  TRP   A CD2 1 
ATOM   725  N NE1 . TRP   A 1 92  ? -15.00335  -24.23887 -106.43538 1.000 21.02159  ? 92  TRP   A NE1 1 
ATOM   726  C CE2 . TRP   A 1 92  ? -14.71687  -25.13314 -107.43270 1.000 22.68521  ? 92  TRP   A CE2 1 
ATOM   727  C CE3 . TRP   A 1 92  ? -13.05101  -25.41246 -109.16875 1.000 20.75600  ? 92  TRP   A CE3 1 
ATOM   728  C CZ2 . TRP   A 1 92  ? -15.39255  -26.30049 -107.81960 1.000 17.67029  ? 92  TRP   A CZ2 1 
ATOM   729  C CZ3 . TRP   A 1 92  ? -13.71888  -26.57337 -109.55452 1.000 21.05869  ? 92  TRP   A CZ3 1 
ATOM   730  C CH2 . TRP   A 1 92  ? -14.88087  -27.00647 -108.87701 1.000 20.38758  ? 92  TRP   A CH2 1 
ATOM   731  N N   . VAL   A 1 93  ? -13.87025  -22.44453 -110.43696 1.000 23.45582  ? 93  VAL   A N   1 
ATOM   732  C CA  . VAL   A 1 93  ? -14.45901  -23.27003 -111.48781 1.000 26.86581  ? 93  VAL   A CA  1 
ATOM   733  C C   . VAL   A 1 93  ? -13.83100  -22.96760 -112.84284 1.000 25.58596  ? 93  VAL   A C   1 
ATOM   734  O O   . VAL   A 1 93  ? -13.66373  -23.86194 -113.68190 1.000 20.76234  ? 93  VAL   A O   1 
ATOM   735  C CB  . VAL   A 1 93  ? -15.98535  -23.06182 -111.51803 1.000 23.25060  ? 93  VAL   A CB  1 
ATOM   736  C CG1 . VAL   A 1 93  ? -16.60454  -23.86326 -112.64811 1.000 24.18495  ? 93  VAL   A CG1 1 
ATOM   737  C CG2 . VAL   A 1 93  ? -16.58172  -23.48452 -110.19978 1.000 21.47567  ? 93  VAL   A CG2 1 
ATOM   738  N N   . PHE   A 1 94  ? -13.47827  -21.71075 -113.08249 1.000 22.14253  ? 94  PHE   A N   1 
ATOM   739  C CA  . PHE   A 1 94  ? -13.03671  -21.29063 -114.40024 1.000 27.37017  ? 94  PHE   A CA  1 
ATOM   740  C C   . PHE   A 1 94  ? -11.52319  -21.12623 -114.50041 1.000 42.07980  ? 94  PHE   A C   1 
ATOM   741  O O   . PHE   A 1 94  ? -11.02346  -20.79085 -115.58453 1.000 36.79423  ? 94  PHE   A O   1 
ATOM   742  C CB  . PHE   A 1 94  ? -13.74213  -19.98305 -114.78285 1.000 23.92278  ? 94  PHE   A CB  1 
ATOM   743  C CG  . PHE   A 1 94  ? -15.22791  -20.01301 -114.55459 1.000 19.89728  ? 94  PHE   A CG  1 
ATOM   744  C CD1 . PHE   A 1 94  ? -16.06584  -20.70708 -115.42489 1.000 21.87063  ? 94  PHE   A CD1 1 
ATOM   745  C CD2 . PHE   A 1 94  ? -15.78915  -19.36556 -113.46693 1.000 22.89526  ? 94  PHE   A CD2 1 
ATOM   746  C CE1 . PHE   A 1 94  ? -17.44594  -20.74558 -115.21666 1.000 21.33627  ? 94  PHE   A CE1 1 
ATOM   747  C CE2 . PHE   A 1 94  ? -17.15972  -19.39614 -113.25344 1.000 23.17598  ? 94  PHE   A CE2 1 
ATOM   748  C CZ  . PHE   A 1 94  ? -17.99109  -20.09454 -114.13086 1.000 17.96404  ? 94  PHE   A CZ  1 
ATOM   749  N N   . GLN   A 1 95  ? -10.78833  -21.39403 -113.41398 1.000 40.31979  ? 95  GLN   A N   1 
ATOM   750  C CA  . GLN   A 1 95  ? -9.37507   -21.07180 -113.26164 1.000 38.78749  ? 95  GLN   A CA  1 
ATOM   751  C C   . GLN   A 1 95  ? -8.50928   -22.32211 -113.16335 1.000 36.92849  ? 95  GLN   A C   1 
ATOM   752  O O   . GLN   A 1 95  ? -8.97470   -23.40306 -112.80120 1.000 32.93547  ? 95  GLN   A O   1 
ATOM   753  C CB  . GLN   A 1 95  ? -9.15122   -20.22708 -112.00967 1.000 33.39396  ? 95  GLN   A CB  1 
ATOM   754  C CG  . GLN   A 1 95  ? -9.49815   -18.78454 -112.19405 1.000 42.43522  ? 95  GLN   A CG  1 
ATOM   755  C CD  . GLN   A 1 95  ? -9.55358   -18.04504 -110.88034 1.000 45.57246  ? 95  GLN   A CD  1 
ATOM   756  O OE1 . GLN   A 1 95  ? -9.41179   -18.64806 -109.80358 1.000 39.47754  ? 95  GLN   A OE1 1 
ATOM   757  N NE2 . GLN   A 1 95  ? -9.77081   -16.72989 -110.95223 1.000 42.59874  ? 95  GLN   A NE2 1 
ATOM   758  N N   . ASP   A 1 96  ? -7.22698   -22.15984 -113.48751 1.000 44.13913  ? 96  ASP   A N   1 
ATOM   759  C CA  . ASP   A 1 96  ? -6.22362   -23.18037 -113.21674 1.000 42.83350  ? 96  ASP   A CA  1 
ATOM   760  C C   . ASP   A 1 96  ? -5.37356   -22.73587 -112.02117 1.000 40.14650  ? 96  ASP   A C   1 
ATOM   761  O O   . ASP   A 1 96  ? -5.71790   -21.79022 -111.30175 1.000 46.61599  ? 96  ASP   A O   1 
ATOM   762  C CB  . ASP   A 1 96  ? -5.39983   -23.47204 -114.47998 1.000 38.87170  ? 96  ASP   A CB  1 
ATOM   763  C CG  . ASP   A 1 96  ? -4.73513   -22.21778 -115.08476 1.000 55.80308  ? 96  ASP   A CG  1 
ATOM   764  O OD1 . ASP   A 1 96  ? -4.43768   -21.24707 -114.35108 1.000 44.84658  ? 96  ASP   A OD1 1 
ATOM   765  O OD2 . ASP   A 1 96  ? -4.49988   -22.21629 -116.31802 1.000 53.87317  ? 96  ASP   A OD2 1 
ATOM   766  N N   . GLY   A 1 97  ? -4.26087   -23.43106 -111.79044 1.000 57.64091  ? 97  GLY   A N   1 
ATOM   767  C CA  . GLY   A 1 97  ? -3.37278   -23.02695 -110.70921 1.000 56.23015  ? 97  GLY   A CA  1 
ATOM   768  C C   . GLY   A 1 97  ? -2.85896   -21.60671 -110.86993 1.000 63.08089  ? 97  GLY   A C   1 
ATOM   769  O O   . GLY   A 1 97  ? -2.70756   -20.87316 -109.88775 1.000 62.51333  ? 97  GLY   A O   1 
ATOM   770  N N   . GLN   A 1 98  ? -2.61012   -21.19160 -112.11311 1.000 60.88039  ? 98  GLN   A N   1 
ATOM   771  C CA  . GLN   A 1 98  ? -2.03158   -19.88836 -112.41727 1.000 59.06380  ? 98  GLN   A CA  1 
ATOM   772  C C   . GLN   A 1 98  ? -3.05426   -18.76033 -112.43963 1.000 61.53072  ? 98  GLN   A C   1 
ATOM   773  O O   . GLN   A 1 98  ? -2.67979   -17.62151 -112.73767 1.000 64.57517  ? 98  GLN   A O   1 
ATOM   774  C CB  . GLN   A 1 98  ? -1.30893   -19.93831 -113.76769 1.000 61.54552  ? 98  GLN   A CB  1 
ATOM   775  C CG  . GLN   A 1 98  ? 0.08133    -20.56360 -113.71285 1.000 81.44174  ? 98  GLN   A CG  1 
ATOM   776  C CD  . GLN   A 1 98  ? 0.07572    -21.95189 -113.09622 1.000 76.17916  ? 98  GLN   A CD  1 
ATOM   777  O OE1 . GLN   A 1 98  ? -0.74337   -22.79979 -113.45961 1.000 73.91791  ? 98  GLN   A OE1 1 
ATOM   778  N NE2 . GLN   A 1 98  ? 0.97993    -22.18618 -112.14708 1.000 62.92623  ? 98  GLN   A NE2 1 
ATOM   779  N N   . GLY   A 1 99  ? -4.32306   -19.03530 -112.14221 1.000 57.34541  ? 99  GLY   A N   1 
ATOM   780  C CA  . GLY   A 1 99  ? -5.33694   -18.00072 -112.18759 1.000 55.40291  ? 99  GLY   A CA  1 
ATOM   781  C C   . GLY   A 1 99  ? -5.81553   -17.63455 -113.57557 1.000 66.76012  ? 99  GLY   A C   1 
ATOM   782  O O   . GLY   A 1 99  ? -6.60350   -16.68863 -113.71381 1.000 58.88830  ? 99  GLY   A O   1 
ATOM   783  N N   . HIS   A 1 100 ? -5.35935   -18.34712 -114.60475 1.000 60.12530  ? 100 HIS   A N   1 
ATOM   784  C CA  . HIS   A 1 100 ? -5.82334   -18.17562 -115.97135 1.000 55.27820  ? 100 HIS   A CA  1 
ATOM   785  C C   . HIS   A 1 100 ? -7.07535   -19.01992 -116.21040 1.000 49.49156  ? 100 HIS   A C   1 
ATOM   786  O O   . HIS   A 1 100 ? -7.44722   -19.86913 -115.39967 1.000 52.77299  ? 100 HIS   A O   1 
ATOM   787  C CB  . HIS   A 1 100 ? -4.72104   -18.56556 -116.95520 1.000 54.42120  ? 100 HIS   A CB  1 
ATOM   788  C CG  . HIS   A 1 100 ? -3.37238   -18.02024 -116.59960 1.000 75.96877  ? 100 HIS   A CG  1 
ATOM   789  N ND1 . HIS   A 1 100 ? -3.20671   -16.87856 -115.84381 1.000 71.91976  ? 100 HIS   A ND1 1 
ATOM   790  C CD2 . HIS   A 1 100 ? -2.12505   -18.45987 -116.89629 1.000 68.90358  ? 100 HIS   A CD2 1 
ATOM   791  C CE1 . HIS   A 1 100 ? -1.91646   -16.63725 -115.69126 1.000 76.94665  ? 100 HIS   A CE1 1 
ATOM   792  N NE2 . HIS   A 1 100 ? -1.23879   -17.58216 -116.31920 1.000 82.58150  ? 100 HIS   A NE2 1 
ATOM   793  N N   . PHE   A 1 101 ? -7.72602   -18.78922 -117.34471 1.000 36.60533  ? 101 PHE   A N   1 
ATOM   794  C CA  . PHE   A 1 101 ? -8.93270   -19.53816 -117.66639 1.000 41.70873  ? 101 PHE   A CA  1 
ATOM   795  C C   . PHE   A 1 101 ? -8.58672   -20.94951 -118.12573 1.000 38.10894  ? 101 PHE   A C   1 
ATOM   796  O O   . PHE   A 1 101 ? -7.56304   -21.18288 -118.77382 1.000 39.35972  ? 101 PHE   A O   1 
ATOM   797  C CB  . PHE   A 1 101 ? -9.74731   -18.81949 -118.74334 1.000 35.73326  ? 101 PHE   A CB  1 
ATOM   798  C CG  . PHE   A 1 101 ? -10.48143  -17.60727 -118.23316 1.000 46.68880  ? 101 PHE   A CG  1 
ATOM   799  C CD1 . PHE   A 1 101 ? -11.10493  -17.63084 -116.99638 1.000 41.73513  ? 101 PHE   A CD1 1 
ATOM   800  C CD2 . PHE   A 1 101 ? -10.53191  -16.44019 -118.98037 1.000 50.03543  ? 101 PHE   A CD2 1 
ATOM   801  C CE1 . PHE   A 1 101 ? -11.77519  -16.52106 -116.51949 1.000 45.76356  ? 101 PHE   A CE1 1 
ATOM   802  C CE2 . PHE   A 1 101 ? -11.20211  -15.32680 -118.50764 1.000 49.53719  ? 101 PHE   A CE2 1 
ATOM   803  C CZ  . PHE   A 1 101 ? -11.82486  -15.36790 -117.27573 1.000 52.33173  ? 101 PHE   A CZ  1 
ATOM   804  N N   . VAL   A 1 102 ? -9.45293   -21.89849 -117.77552 1.000 30.66412  ? 102 VAL   A N   1 
ATOM   805  C CA  . VAL   A 1 102 ? -9.21636   -23.29781 -118.11051 1.000 29.15616  ? 102 VAL   A CA  1 
ATOM   806  C C   . VAL   A 1 102 ? -9.65237   -23.58330 -119.53361 1.000 24.33436  ? 102 VAL   A C   1 
ATOM   807  O O   . VAL   A 1 102 ? -10.30388  -22.76450 -120.18499 1.000 31.12664  ? 102 VAL   A O   1 
ATOM   808  C CB  . VAL   A 1 102 ? -9.93567   -24.27433 -117.15404 1.000 29.09560  ? 102 VAL   A CB  1 
ATOM   809  C CG1 . VAL   A 1 102 ? -9.49080   -24.05924 -115.74174 1.000 32.01711  ? 102 VAL   A CG1 1 
ATOM   810  C CG2 . VAL   A 1 102 ? -11.44192  -24.16960 -117.28694 1.000 29.55461  ? 102 VAL   A CG2 1 
ATOM   811  N N   . SER   A 1 103 ? -9.29896   -24.76867 -120.00051 1.000 31.76062  ? 103 SER   A N   1 
ATOM   812  C CA  . SER   A 1 103 ? -9.68481   -25.27171 -121.29918 1.000 29.57973  ? 103 SER   A CA  1 
ATOM   813  C C   . SER   A 1 103 ? -11.19449  -25.51739 -121.36339 1.000 32.74824  ? 103 SER   A C   1 
ATOM   814  O O   . SER   A 1 103 ? -11.86091  -25.71851 -120.34741 1.000 31.42566  ? 103 SER   A O   1 
ATOM   815  C CB  . SER   A 1 103 ? -8.92488   -26.56931 -121.56803 1.000 21.32180  ? 103 SER   A CB  1 
ATOM   816  O OG  . SER   A 1 103 ? -9.22206   -27.09110 -122.84761 1.000 43.14440  ? 103 SER   A OG  1 
ATOM   817  N N   . ARG   A 1 104 ? -11.73042  -25.51234 -122.58759 1.000 30.26924  ? 104 ARG   A N   1 
ATOM   818  C CA  . ARG   A 1 104 ? -13.06181  -26.05985 -122.80914 1.000 29.00196  ? 104 ARG   A CA  1 
ATOM   819  C C   . ARG   A 1 104 ? -13.19627  -27.42843 -122.15295 1.000 39.19835  ? 104 ARG   A C   1 
ATOM   820  O O   . ARG   A 1 104 ? -14.12553  -27.66751 -121.37400 1.000 37.30043  ? 104 ARG   A O   1 
ATOM   821  C CB  . ARG   A 1 104 ? -13.35686  -26.16109 -124.30733 1.000 27.36673  ? 104 ARG   A CB  1 
ATOM   822  C CG  . ARG   A 1 104 ? -14.49117  -27.13379 -124.64175 1.000 28.02485  ? 104 ARG   A CG  1 
ATOM   823  C CD  . ARG   A 1 104 ? -14.65239  -27.38359 -126.13336 1.000 23.04498  ? 104 ARG   A CD  1 
ATOM   824  N NE  . ARG   A 1 104 ? -15.71966  -28.34941 -126.41489 1.000 28.13575  ? 104 ARG   A NE  1 
ATOM   825  C CZ  . ARG   A 1 104 ? -16.99681  -28.02131 -126.61704 1.000 30.35460  ? 104 ARG   A CZ  1 
ATOM   826  N NH1 . ARG   A 1 104 ? -17.36805  -26.74570 -126.57858 1.000 29.07727  ? 104 ARG   A NH1 1 
ATOM   827  N NH2 . ARG   A 1 104 ? -17.91073  -28.96193 -126.86325 1.000 23.82482  ? 104 ARG   A NH2 1 
ATOM   828  N N   . ASP   A 1 105 ? -12.25705  -28.33593 -122.44503 1.000 31.99539  ? 105 ASP   A N   1 
ATOM   829  C CA  . ASP   A 1 105 ? -12.36446  -29.71188 -121.96398 1.000 38.17206  ? 105 ASP   A CA  1 
ATOM   830  C C   . ASP   A 1 105 ? -12.28292  -29.79368 -120.44211 1.000 34.65377  ? 105 ASP   A C   1 
ATOM   831  O O   . ASP   A 1 105 ? -12.92440  -30.66233 -119.83354 1.000 26.92968  ? 105 ASP   A O   1 
ATOM   832  C CB  . ASP   A 1 105 ? -11.27264  -30.58145 -122.60592 1.000 31.32979  ? 105 ASP   A CB  1 
ATOM   833  C CG  . ASP   A 1 105 ? -11.50326  -30.80455 -124.09062 1.000 36.11631  ? 105 ASP   A CG  1 
ATOM   834  O OD1 . ASP   A 1 105 ? -12.49557  -30.27202 -124.62987 1.000 43.09113  ? 105 ASP   A OD1 1 
ATOM   835  O OD2 . ASP   A 1 105 ? -10.69557  -31.51206 -124.72557 1.000 42.34573  ? 105 ASP   A OD2 1 
ATOM   836  N N   . VAL   A 1 106 ? -11.50653  -28.90923 -119.81080 1.000 28.47588  ? 106 VAL   A N   1 
ATOM   837  C CA  . VAL   A 1 106 ? -11.41290  -28.92511 -118.35210 1.000 27.94124  ? 106 VAL   A CA  1 
ATOM   838  C C   . VAL   A 1 106 ? -12.69017  -28.36998 -117.72263 1.000 33.98160  ? 106 VAL   A C   1 
ATOM   839  O O   . VAL   A 1 106 ? -13.18546  -28.89610 -116.71535 1.000 27.66240  ? 106 VAL   A O   1 
ATOM   840  C CB  . VAL   A 1 106 ? -10.16263  -28.15647 -117.89070 1.000 28.17548  ? 106 VAL   A CB  1 
ATOM   841  C CG1 . VAL   A 1 106 ? -10.19180  -27.90676 -116.38941 1.000 26.15668  ? 106 VAL   A CG1 1 
ATOM   842  C CG2 . VAL   A 1 106 ? -8.92240   -28.93317 -118.27013 1.000 22.98545  ? 106 VAL   A CG2 1 
ATOM   843  N N   . LEU   A 1 107 ? -13.25493  -27.30806 -118.29993 1.000 29.84391  ? 107 LEU   A N   1 
ATOM   844  C CA  . LEU   A 1 107 ? -14.50469  -26.80735 -117.74421 1.000 35.30063  ? 107 LEU   A CA  1 
ATOM   845  C C   . LEU   A 1 107 ? -15.62433  -27.83442 -117.91882 1.000 30.09783  ? 107 LEU   A C   1 
ATOM   846  O O   . LEU   A 1 107 ? -16.43104  -28.03580 -117.00433 1.000 22.62482  ? 107 LEU   A O   1 
ATOM   847  C CB  . LEU   A 1 107 ? -14.86767  -25.45893 -118.36740 1.000 25.37045  ? 107 LEU   A CB  1 
ATOM   848  C CG  . LEU   A 1 107 ? -15.97686  -24.73933 -117.58489 1.000 28.41292  ? 107 LEU   A CG  1 
ATOM   849  C CD1 . LEU   A 1 107 ? -15.70183  -24.76956 -116.07891 1.000 17.67340  ? 107 LEU   A CD1 1 
ATOM   850  C CD2 . LEU   A 1 107 ? -16.17885  -23.31208 -118.07144 1.000 23.51767  ? 107 LEU   A CD2 1 
ATOM   851  N N   . LEU   A 1 108 ? -15.64858  -28.53859 -119.05724 1.000 25.56720  ? 108 LEU   A N   1 
ATOM   852  C CA  . LEU   A 1 108 ? -16.61389  -29.61885 -119.24161 1.000 24.97622  ? 108 LEU   A CA  1 
ATOM   853  C C   . LEU   A 1 108 ? -16.46560  -30.69626 -118.17272 1.000 22.75164  ? 108 LEU   A C   1 
ATOM   854  O O   . LEU   A 1 108 ? -17.46606  -31.19851 -117.65015 1.000 24.74829  ? 108 LEU   A O   1 
ATOM   855  C CB  . LEU   A 1 108 ? -16.46501  -30.23225 -120.62866 1.000 21.21032  ? 108 LEU   A CB  1 
ATOM   856  C CG  . LEU   A 1 108 ? -17.09603  -29.45944 -121.78798 1.000 29.59407  ? 108 LEU   A CG  1 
ATOM   857  C CD1 . LEU   A 1 108 ? -16.96002  -30.25725 -123.08768 1.000 23.92669  ? 108 LEU   A CD1 1 
ATOM   858  C CD2 . LEU   A 1 108 ? -18.56183  -29.10985 -121.50396 1.000 25.12664  ? 108 LEU   A CD2 1 
ATOM   859  N N   . GLU   A 1 109 ? -15.22861  -31.07978 -117.84611 1.000 24.08445  ? 109 GLU   A N   1 
ATOM   860  C CA  . GLU   A 1 109 ? -15.03030  -32.09925 -116.81921 1.000 29.67400  ? 109 GLU   A CA  1 
ATOM   861  C C   . GLU   A 1 109 ? -15.51113  -31.61089 -115.46119 1.000 23.90503  ? 109 GLU   A C   1 
ATOM   862  O O   . GLU   A 1 109 ? -16.11834  -32.37212 -114.70243 1.000 20.11058  ? 109 GLU   A O   1 
ATOM   863  C CB  . GLU   A 1 109 ? -13.55602  -32.50682 -116.73605 1.000 29.92221  ? 109 GLU   A CB  1 
ATOM   864  C CG  . GLU   A 1 109 ? -13.10749  -33.48931 -117.80055 1.000 45.52014  ? 109 GLU   A CG  1 
ATOM   865  C CD  . GLU   A 1 109 ? -11.59043  -33.65251 -117.85116 1.000 72.32398  ? 109 GLU   A CD  1 
ATOM   866  O OE1 . GLU   A 1 109 ? -10.88569  -33.05315 -116.99874 1.000 55.19032  ? 109 GLU   A OE1 1 
ATOM   867  O OE2 . GLU   A 1 109 ? -11.10532  -34.37238 -118.75737 1.000 74.92261  ? 109 GLU   A OE2 1 
ATOM   868  N N   . ARG   A 1 110 ? -15.22491  -30.35100 -115.13100 1.000 23.21782  ? 110 ARG   A N   1 
ATOM   869  C CA  . ARG   A 1 110 ? -15.70568  -29.77918 -113.88022 1.000 27.34790  ? 110 ARG   A CA  1 
ATOM   870  C C   . ARG   A 1 110 ? -17.23162  -29.68506 -113.86560 1.000 26.22743  ? 110 ARG   A C   1 
ATOM   871  O O   . ARG   A 1 110 ? -17.87830  -30.04647 -112.87485 1.000 26.77471  ? 110 ARG   A O   1 
ATOM   872  C CB  . ARG   A 1 110 ? -15.06015  -28.41195 -113.67277 1.000 19.37439  ? 110 ARG   A CB  1 
ATOM   873  C CG  . ARG   A 1 110 ? -13.56544  -28.50972 -113.52217 1.000 28.85379  ? 110 ARG   A CG  1 
ATOM   874  C CD  . ARG   A 1 110 ? -12.91772  -27.16647 -113.27424 1.000 28.20981  ? 110 ARG   A CD  1 
ATOM   875  N NE  . ARG   A 1 110 ? -11.49438  -27.33368 -113.00645 1.000 33.80129  ? 110 ARG   A NE  1 
ATOM   876  C CZ  . ARG   A 1 110 ? -10.65280  -26.33937 -112.75646 1.000 29.82120  ? 110 ARG   A CZ  1 
ATOM   877  N NH1 . ARG   A 1 110 ? -11.08901  -25.08797 -112.73328 1.000 27.98069  ? 110 ARG   A NH1 1 
ATOM   878  N NH2 . ARG   A 1 110 ? -9.37323   -26.60166 -112.52616 1.000 37.20374  ? 110 ARG   A NH2 1 
ATOM   879  N N   . MET   A 1 111 ? -17.82633  -29.20142 -114.95803 1.000 21.41710  ? 111 MET   A N   1 
ATOM   880  C CA  . MET   A 1 111 ? -19.28125  -29.17163 -115.04424 1.000 18.44354  ? 111 MET   A CA  1 
ATOM   881  C C   . MET   A 1 111 ? -19.85524  -30.57088 -114.85414 1.000 20.50098  ? 111 MET   A C   1 
ATOM   882  O O   . MET   A 1 111 ? -20.80061  -30.76289 -114.08557 1.000 20.02103  ? 111 MET   A O   1 
ATOM   883  C CB  . MET   A 1 111 ? -19.72754  -28.57253 -116.38641 1.000 17.52686  ? 111 MET   A CB  1 
ATOM   884  C CG  . MET   A 1 111 ? -21.25654  -28.46180 -116.57676 1.000 14.70603  ? 111 MET   A CG  1 
ATOM   885  S SD  . MET   A 1 111 ? -21.79921  -28.20220 -118.29246 1.000 23.67809  ? 111 MET   A SD  1 
ATOM   886  C CE  . MET   A 1 111 ? -21.49745  -26.45044 -118.42527 1.000 16.45643  ? 111 MET   A CE  1 
ATOM   887  N N   . LYS   A 1 112 ? -19.27743  -31.57178 -115.52692 1.000 22.91680  ? 112 LYS   A N   1 
ATOM   888  C CA  . LYS   A 1 112 ? -19.82547  -32.92110 -115.41773 1.000 18.25079  ? 112 LYS   A CA  1 
ATOM   889  C C   . LYS   A 1 112 ? -19.66875  -33.46357 -114.00592 1.000 19.80066  ? 112 LYS   A C   1 
ATOM   890  O O   . LYS   A 1 112 ? -20.60320  -34.04871 -113.44867 1.000 18.08542  ? 112 LYS   A O   1 
ATOM   891  C CB  . LYS   A 1 112 ? -19.17050  -33.86380 -116.42532 1.000 19.33581  ? 112 LYS   A CB  1 
ATOM   892  C CG  . LYS   A 1 112 ? -19.64414  -35.30248 -116.27798 1.000 24.52391  ? 112 LYS   A CG  1 
ATOM   893  C CD  . LYS   A 1 112 ? -19.32258  -36.15335 -117.49222 1.000 25.38841  ? 112 LYS   A CD  1 
ATOM   894  C CE  . LYS   A 1 112 ? -19.91597  -37.55219 -117.35142 1.000 36.10164  ? 112 LYS   A CE  1 
ATOM   895  N NZ  . LYS   A 1 112 ? -19.55074  -38.45213 -118.48895 1.000 50.96713  ? 112 LYS   A NZ  1 
ATOM   896  N N   . CYS   A 1 113 ? -18.50877  -33.25711 -113.39843 1.000 16.98295  ? 113 CYS   A N   1 
ATOM   897  C CA  . CYS   A 1 113 ? -18.30910  -33.75790 -112.05018 1.000 21.10773  ? 113 CYS   A CA  1 
ATOM   898  C C   . CYS   A 1 113 ? -19.32357  -33.14316 -111.09191 1.000 20.55720  ? 113 CYS   A C   1 
ATOM   899  O O   . CYS   A 1 113 ? -19.97515  -33.85036 -110.31488 1.000 17.10148  ? 113 CYS   A O   1 
ATOM   900  C CB  . CYS   A 1 113 ? -16.87742  -33.47137 -111.59935 1.000 21.15874  ? 113 CYS   A CB  1 
ATOM   901  S SG  . CYS   A 1 113 ? -16.43856  -34.42970 -110.16264 1.000 34.44242  ? 113 CYS   A SG  1 
ATOM   902  N N   . HIS   A 1 114 ? -19.48177  -31.82093 -111.15130 1.000 20.56689  ? 114 HIS   A N   1 
ATOM   903  C CA  . HIS   A 1 114 ? -20.43705  -31.14301 -110.28444 1.000 18.09954  ? 114 HIS   A CA  1 
ATOM   904  C C   . HIS   A 1 114 ? -21.84927  -31.67631 -110.50016 1.000 16.39378  ? 114 HIS   A C   1 
ATOM   905  O O   . HIS   A 1 114 ? -22.52914  -32.07194 -109.55148 1.000 20.33431  ? 114 HIS   A O   1 
ATOM   906  C CB  . HIS   A 1 114 ? -20.38546  -29.64065 -110.54482 1.000 18.23760  ? 114 HIS   A CB  1 
ATOM   907  C CG  . HIS   A 1 114 ? -21.29162  -28.85622 -109.65550 1.000 26.57013  ? 114 HIS   A CG  1 
ATOM   908  N ND1 . HIS   A 1 114 ? -20.92160  -28.45373 -108.39048 1.000 18.81034  ? 114 HIS   A ND1 1 
ATOM   909  C CD2 . HIS   A 1 114 ? -22.56346  -28.42575 -109.83317 1.000 16.21027  ? 114 HIS   A CD2 1 
ATOM   910  C CE1 . HIS   A 1 114 ? -21.91748  -27.79194 -107.83287 1.000 17.35681  ? 114 HIS   A CE1 1 
ATOM   911  N NE2 . HIS   A 1 114 ? -22.92589  -27.76504 -108.68514 1.000 19.62876  ? 114 HIS   A NE2 1 
ATOM   912  N N   . ILE   A 1 115 ? -22.29581  -31.71791 -111.75444 1.000 21.13949  ? 115 ILE   A N   1 
ATOM   913  C CA  . ILE   A 1 115 ? -23.66274  -32.13287 -112.05344 1.000 17.87830  ? 115 ILE   A CA  1 
ATOM   914  C C   . ILE   A 1 115 ? -23.89376  -33.57275 -111.60985 1.000 18.83188  ? 115 ILE   A C   1 
ATOM   915  O O   . ILE   A 1 115 ? -24.94444  -33.90441 -111.04773 1.000 21.85155  ? 115 ILE   A O   1 
ATOM   916  C CB  . ILE   A 1 115 ? -23.94926  -31.92912 -113.55381 1.000 11.23774  ? 115 ILE   A CB  1 
ATOM   917  C CG1 . ILE   A 1 115 ? -24.09178  -30.43969 -113.85789 1.000 12.03390  ? 115 ILE   A CG1 1 
ATOM   918  C CG2 . ILE   A 1 115 ? -25.16529  -32.71534 -113.98987 1.000 13.43864  ? 115 ILE   A CG2 1 
ATOM   919  C CD1 . ILE   A 1 115 ? -24.32892  -30.10804 -115.34273 1.000 15.96047  ? 115 ILE   A CD1 1 
ATOM   920  N N   A SER   A 1 116 ? -22.90855  -34.44339 -111.83738 0.416 17.92609  ? 116 SER   A N   1 
ATOM   921  N N   B SER   A 1 116 ? -22.91271  -34.44760 -111.83457 0.584 18.02999  ? 116 SER   A N   1 
ATOM   922  C CA  A SER   A 1 116 ? -23.03899  -35.84369 -111.44675 0.416 18.15300  ? 116 SER   A CA  1 
ATOM   923  C CA  B SER   A 1 116 ? -23.07775  -35.84448 -111.44511 0.584 17.69777  ? 116 SER   A CA  1 
ATOM   924  C C   A SER   A 1 116 ? -23.13828  -35.99258 -109.93139 0.416 18.48302  ? 116 SER   A C   1 
ATOM   925  C C   B SER   A 1 116 ? -23.13211  -36.00674 -109.92630 0.584 18.45627  ? 116 SER   A C   1 
ATOM   926  O O   A SER   A 1 116 ? -24.00068  -36.71486 -109.42274 0.416 17.86012  ? 116 SER   A O   1 
ATOM   927  O O   B SER   A 1 116 ? -23.96151  -36.76085 -109.41079 0.584 17.92041  ? 116 SER   A O   1 
ATOM   928  C CB  A SER   A 1 116 ? -21.85248  -36.64273 -111.98497 0.416 17.79438  ? 116 SER   A CB  1 
ATOM   929  C CB  B SER   A 1 116 ? -21.95251  -36.69346 -112.03085 0.584 17.78805  ? 116 SER   A CB  1 
ATOM   930  O OG  A SER   A 1 116 ? -21.76344  -36.52064 -113.39148 0.416 20.77824  ? 116 SER   A OG  1 
ATOM   931  O OG  B SER   A 1 116 ? -22.30509  -38.06632 -111.98392 0.584 23.01541  ? 116 SER   A OG  1 
ATOM   932  N N   . THR   A 1 117 ? -22.25193  -35.32431 -109.19230 1.000 14.95917  ? 117 THR   A N   1 
ATOM   933  C CA  . THR   A 1 117 ? -22.24905  -35.46701 -107.73892 1.000 16.98753  ? 117 THR   A CA  1 
ATOM   934  C C   . THR   A 1 117 ? -23.53844  -34.91114 -107.13188 1.000 17.14973  ? 117 THR   A C   1 
ATOM   935  O O   . THR   A 1 117 ? -24.17428  -35.56074 -106.29341 1.000 14.44940  ? 117 THR   A O   1 
ATOM   936  C CB  . THR   A 1 117 ? -21.01460  -34.76994 -107.14023 1.000 17.94644  ? 117 THR   A CB  1 
ATOM   937  O OG1 . THR   A 1 117 ? -19.84951  -35.11487 -107.89882 1.000 14.22624  ? 117 THR   A OG1 1 
ATOM   938  C CG2 . THR   A 1 117 ? -20.79704  -35.18442 -105.69108 1.000 11.83189  ? 117 THR   A CG2 1 
ATOM   939  N N   . VAL   A 1 118 ? -23.95242  -33.72099 -107.56793 1.000 13.84789  ? 118 VAL   A N   1 
ATOM   940  C CA  . VAL   A 1 118 ? -25.14161  -33.08925 -107.00627 1.000 17.83244  ? 118 VAL   A CA  1 
ATOM   941  C C   . VAL   A 1 118 ? -26.40047  -33.86867 -107.38981 1.000 17.91121  ? 118 VAL   A C   1 
ATOM   942  O O   . VAL   A 1 118 ? -27.20290  -34.23800 -106.52747 1.000 15.97579  ? 118 VAL   A O   1 
ATOM   943  C CB  . VAL   A 1 118 ? -25.22121  -31.61821 -107.45862 1.000 14.18327  ? 118 VAL   A CB  1 
ATOM   944  C CG1 . VAL   A 1 118 ? -26.53597  -30.99536 -107.00845 1.000 15.18218  ? 118 VAL   A CG1 1 
ATOM   945  C CG2 . VAL   A 1 118 ? -24.05254  -30.84310 -106.91763 1.000 13.34139  ? 118 VAL   A CG2 1 
ATOM   946  N N   . VAL   A 1 119 ? -26.58436  -34.14411 -108.68409 1.000 14.35120  ? 119 VAL   A N   1 
ATOM   947  C CA  . VAL   A 1 119 ? -27.82919  -34.75898 -109.13240 1.000 16.12766  ? 119 VAL   A CA  1 
ATOM   948  C C   . VAL   A 1 119 ? -27.95375  -36.18550 -108.60480 1.000 19.65131  ? 119 VAL   A C   1 
ATOM   949  O O   . VAL   A 1 119 ? -29.03925  -36.61348 -108.18977 1.000 19.48245  ? 119 VAL   A O   1 
ATOM   950  C CB  . VAL   A 1 119 ? -27.92920  -34.71157 -110.66690 1.000 13.65456  ? 119 VAL   A CB  1 
ATOM   951  C CG1 . VAL   A 1 119 ? -29.08632  -35.55281 -111.15382 1.000 12.10248  ? 119 VAL   A CG1 1 
ATOM   952  C CG2 . VAL   A 1 119 ? -28.06236  -33.27344 -111.13993 1.000 12.77564  ? 119 VAL   A CG2 1 
ATOM   953  N N   . ARG   A 1 120 ? -26.85551  -36.94810 -108.59367 1.000 19.04222  ? 120 ARG   A N   1 
ATOM   954  C CA  A ARG   A 1 120 ? -26.94785  -38.31687 -108.09607 0.574 19.38401  ? 120 ARG   A CA  1 
ATOM   955  C CA  B ARG   A 1 120 ? -26.93369  -38.31862 -108.09027 0.426 19.39949  ? 120 ARG   A CA  1 
ATOM   956  C C   . ARG   A 1 120 ? -27.25117  -38.35615 -106.59918 1.000 18.86446  ? 120 ARG   A C   1 
ATOM   957  O O   . ARG   A 1 120 ? -27.93612  -39.27495 -106.13895 1.000 12.88193  ? 120 ARG   A O   1 
ATOM   958  C CB  A ARG   A 1 120 ? -25.66302  -39.08883 -108.41679 0.574 19.55927  ? 120 ARG   A CB  1 
ATOM   959  C CB  B ARG   A 1 120 ? -25.63112  -39.07616 -108.37313 0.426 19.52778  ? 120 ARG   A CB  1 
ATOM   960  C CG  A ARG   A 1 120 ? -25.56546  -39.53785 -109.88507 0.574 17.86373  ? 120 ARG   A CG  1 
ATOM   961  C CG  B ARG   A 1 120 ? -25.66927  -40.55519 -107.98425 0.426 26.32646  ? 120 ARG   A CG  1 
ATOM   962  C CD  A ARG   A 1 120 ? -24.43768  -40.52854 -110.11340 0.574 19.28616  ? 120 ARG   A CD  1 
ATOM   963  C CD  B ARG   A 1 120 ? -24.81828  -41.43580 -108.90790 0.426 26.94075  ? 120 ARG   A CD  1 
ATOM   964  N NE  A ARG   A 1 120 ? -23.98578  -40.52404 -111.50448 0.574 22.85798  ? 120 ARG   A NE  1 
ATOM   965  N NE  B ARG   A 1 120 ? -25.28836  -42.81943 -108.89722 0.426 26.22701  ? 120 ARG   A NE  1 
ATOM   966  C CZ  A ARG   A 1 120 ? -24.50339  -41.29001 -112.46221 0.574 26.25122  ? 120 ARG   A CZ  1 
ATOM   967  C CZ  B ARG   A 1 120 ? -25.93333  -43.39500 -109.90655 0.426 32.43459  ? 120 ARG   A CZ  1 
ATOM   968  N NH1 A ARG   A 1 120 ? -25.49894  -42.12226 -112.18024 0.574 28.58426  ? 120 ARG   A NH1 1 
ATOM   969  N NH1 B ARG   A 1 120 ? -26.17447  -42.70548 -111.01555 0.426 33.61713  ? 120 ARG   A NH1 1 
ATOM   970  N NH2 A ARG   A 1 120 ? -24.03741  -41.21844 -113.70390 0.574 21.03888  ? 120 ARG   A NH2 1 
ATOM   971  N NH2 B ARG   A 1 120 ? -26.33455  -44.65838 -109.81107 0.426 31.23308  ? 120 ARG   A NH2 1 
ATOM   972  N N   . ARG   A 1 121 ? -26.77158  -37.37243 -105.82145 1.000 13.49107  ? 121 ARG   A N   1 
ATOM   973  C CA  . ARG   A 1 121 ? -27.05763  -37.41460 -104.38807 1.000 20.01232  ? 121 ARG   A CA  1 
ATOM   974  C C   . ARG   A 1 121 ? -28.55829  -37.37379 -104.11621 1.000 23.11245  ? 121 ARG   A C   1 
ATOM   975  O O   . ARG   A 1 121 ? -29.05294  -38.05190 -103.21103 1.000 20.24216  ? 121 ARG   A O   1 
ATOM   976  C CB  . ARG   A 1 121 ? -26.37811  -36.27031 -103.64960 1.000 12.40956  ? 121 ARG   A CB  1 
ATOM   977  C CG  . ARG   A 1 121 ? -26.67691  -36.29339 -102.15392 1.000 13.86354  ? 121 ARG   A CG  1 
ATOM   978  C CD  . ARG   A 1 121 ? -25.88648  -35.22360 -101.43605 1.000 14.38178  ? 121 ARG   A CD  1 
ATOM   979  N NE  . ARG   A 1 121 ? -26.02812  -35.23402 -99.98658  1.000 11.83302  ? 121 ARG   A NE  1 
ATOM   980  C CZ  . ARG   A 1 121 ? -25.35866  -36.04478 -99.16283  1.000 20.32003  ? 121 ARG   A CZ  1 
ATOM   981  N NH1 . ARG   A 1 121 ? -24.51415  -36.96070 -99.63163  1.000 10.18354  ? 121 ARG   A NH1 1 
ATOM   982  N NH2 . ARG   A 1 121 ? -25.53979  -35.94306 -97.85281  1.000 13.01179  ? 121 ARG   A NH2 1 
ATOM   983  N N   . TYR   A 1 122 ? -29.29699  -36.58698 -104.88900 1.000 15.89466  ? 122 TYR   A N   1 
ATOM   984  C CA  . TYR   A 1 122 ? -30.69932  -36.33884 -104.61344 1.000 19.02323  ? 122 TYR   A CA  1 
ATOM   985  C C   . TYR   A 1 122 ? -31.60917  -37.06630 -105.58732 1.000 22.47002  ? 122 TYR   A C   1 
ATOM   986  O O   . TYR   A 1 122 ? -32.82200  -36.83315 -105.58660 1.000 26.18237  ? 122 TYR   A O   1 
ATOM   987  C CB  . TYR   A 1 122 ? -30.95101  -34.83569 -104.62970 1.000 17.84902  ? 122 TYR   A CB  1 
ATOM   988  C CG  . TYR   A 1 122 ? -30.15587  -34.12960 -103.55781 1.000 19.97864  ? 122 TYR   A CG  1 
ATOM   989  C CD1 . TYR   A 1 122 ? -30.38306  -34.40946 -102.20625 1.000 15.10650  ? 122 TYR   A CD1 1 
ATOM   990  C CD2 . TYR   A 1 122 ? -29.17430  -33.19307 -103.88564 1.000 14.52653  ? 122 TYR   A CD2 1 
ATOM   991  C CE1 . TYR   A 1 122 ? -29.66301  -33.76079 -101.21265 1.000 18.39311  ? 122 TYR   A CE1 1 
ATOM   992  C CE2 . TYR   A 1 122 ? -28.43418  -32.54171 -102.89316 1.000 12.42849  ? 122 TYR   A CE2 1 
ATOM   993  C CZ  . TYR   A 1 122 ? -28.68443  -32.83511 -101.56031 1.000 17.29240  ? 122 TYR   A CZ  1 
ATOM   994  O OH  . TYR   A 1 122 ? -27.98012  -32.20087 -100.56286 1.000 15.72544  ? 122 TYR   A OH  1 
ATOM   995  N N   . LYS   A 1 123 ? -31.03448  -37.91830 -106.43130 1.000 23.20033  ? 123 LYS   A N   1 
ATOM   996  C CA  . LYS   A 1 123 ? -31.79142  -38.80633 -107.29923 1.000 22.33823  ? 123 LYS   A CA  1 
ATOM   997  C C   . LYS   A 1 123 ? -32.90907  -39.49749 -106.51967 1.000 22.14649  ? 123 LYS   A C   1 
ATOM   998  O O   . LYS   A 1 123 ? -32.68983  -40.01871 -105.42646 1.000 23.74685  ? 123 LYS   A O   1 
ATOM   999  C CB  . LYS   A 1 123 ? -30.82157  -39.82624 -107.90395 1.000 17.66460  ? 123 LYS   A CB  1 
ATOM   1000 C CG  . LYS   A 1 123 ? -31.44404  -40.92559 -108.70772 1.000 26.97509  ? 123 LYS   A CG  1 
ATOM   1001 C CD  . LYS   A 1 123 ? -30.64080  -41.16125 -109.97554 1.000 35.42762  ? 123 LYS   A CD  1 
ATOM   1002 C CE  . LYS   A 1 123 ? -29.60400  -42.25696 -109.79936 1.000 39.97474  ? 123 LYS   A CE  1 
ATOM   1003 N NZ  . LYS   A 1 123 ? -29.14148  -42.75385 -111.13095 1.000 49.39477  ? 123 LYS   A NZ  1 
ATOM   1004 N N   . GLY   A 1 124 ? -34.12368  -39.46711 -107.06492 1.000 25.24862  ? 124 GLY   A N   1 
ATOM   1005 C CA  . GLY   A 1 124 ? -35.24839  -40.06979 -106.37807 1.000 21.83922  ? 124 GLY   A CA  1 
ATOM   1006 C C   . GLY   A 1 124 ? -35.85218  -39.25769 -105.24728 1.000 24.76844  ? 124 GLY   A C   1 
ATOM   1007 O O   . GLY   A 1 124 ? -36.85074  -39.68942 -104.66177 1.000 32.49579  ? 124 GLY   A O   1 
ATOM   1008 N N   . LYS   A 1 125 ? -35.27503  -38.11851 -104.89272 1.000 20.30926  ? 125 LYS   A N   1 
ATOM   1009 C CA  . LYS   A 1 125 ? -35.95607  -37.16924 -104.02640 1.000 23.53391  ? 125 LYS   A CA  1 
ATOM   1010 C C   . LYS   A 1 125 ? -36.27011  -35.86074 -104.72846 1.000 26.00934  ? 125 LYS   A C   1 
ATOM   1011 O O   . LYS   A 1 125 ? -37.28270  -35.24305 -104.42247 1.000 21.68705  ? 125 LYS   A O   1 
ATOM   1012 C CB  . LYS   A 1 125 ? -35.12281  -36.88260 -102.77057 1.000 25.51340  ? 125 LYS   A CB  1 
ATOM   1013 C CG  . LYS   A 1 125 ? -34.53267  -38.13005 -102.12103 1.000 28.75841  ? 125 LYS   A CG  1 
ATOM   1014 C CD  . LYS   A 1 125 ? -34.23090  -37.91583 -100.64787 1.000 31.82721  ? 125 LYS   A CD  1 
ATOM   1015 C CE  . LYS   A 1 125 ? -33.17422  -38.89611 -100.14795 1.000 33.43899  ? 125 LYS   A CE  1 
ATOM   1016 N NZ  . LYS   A 1 125 ? -32.89695  -38.71427 -98.68487  1.000 47.48826  ? 125 LYS   A NZ  1 
ATOM   1017 N N   . ILE   A 1 126 ? -35.44377  -35.44243 -105.68127 1.000 22.24016  ? 126 ILE   A N   1 
ATOM   1018 C CA  . ILE   A 1 126 ? -35.67849  -34.23016 -106.45104 1.000 16.71497  ? 126 ILE   A CA  1 
ATOM   1019 C C   . ILE   A 1 126 ? -36.19193  -34.64176 -107.82323 1.000 19.53184  ? 126 ILE   A C   1 
ATOM   1020 O O   . ILE   A 1 126 ? -35.52998  -35.40341 -108.53947 1.000 20.37199  ? 126 ILE   A O   1 
ATOM   1021 C CB  . ILE   A 1 126 ? -34.40003  -33.38524 -106.55199 1.000 18.55114  ? 126 ILE   A CB  1 
ATOM   1022 C CG1 . ILE   A 1 126 ? -34.00976  -32.86820 -105.15670 1.000 19.62537  ? 126 ILE   A CG1 1 
ATOM   1023 C CG2 . ILE   A 1 126 ? -34.58454  -32.25583 -107.52565 1.000 14.57689  ? 126 ILE   A CG2 1 
ATOM   1024 C CD1 . ILE   A 1 126 ? -32.84340  -31.89732 -105.15270 1.000 12.55546  ? 126 ILE   A CD1 1 
ATOM   1025 N N   . TYR   A 1 127 ? -37.37205  -34.14574 -108.20293 1.000 18.92434  ? 127 TYR   A N   1 
ATOM   1026 C CA  . TYR   A 1 127 ? -37.96373  -34.60234 -109.44695 1.000 14.33105  ? 127 TYR   A CA  1 
ATOM   1027 C C   . TYR   A 1 127 ? -37.67587  -33.69708 -110.63239 1.000 18.28970  ? 127 TYR   A C   1 
ATOM   1028 O O   . TYR   A 1 127 ? -37.95210  -34.10429 -111.76504 1.000 18.28509  ? 127 TYR   A O   1 
ATOM   1029 C CB  . TYR   A 1 127 ? -39.46587  -34.78660 -109.30483 1.000 17.23920  ? 127 TYR   A CB  1 
ATOM   1030 C CG  . TYR   A 1 127 ? -40.30756  -33.54225 -109.45107 1.000 20.78936  ? 127 TYR   A CG  1 
ATOM   1031 C CD1 . TYR   A 1 127 ? -40.31125  -32.57074 -108.45927 1.000 16.42146  ? 127 TYR   A CD1 1 
ATOM   1032 C CD2 . TYR   A 1 127 ? -41.13343  -33.35745 -110.57199 1.000 19.90203  ? 127 TYR   A CD2 1 
ATOM   1033 C CE1 . TYR   A 1 127 ? -41.11142  -31.43001 -108.57243 1.000 23.36985  ? 127 TYR   A CE1 1 
ATOM   1034 C CE2 . TYR   A 1 127 ? -41.94290  -32.22695 -110.69893 1.000 24.98509  ? 127 TYR   A CE2 1 
ATOM   1035 C CZ  . TYR   A 1 127 ? -41.92732  -31.26584 -109.69123 1.000 32.00831  ? 127 TYR   A CZ  1 
ATOM   1036 O OH  . TYR   A 1 127 ? -42.71418  -30.13756 -109.78491 1.000 25.74342  ? 127 TYR   A OH  1 
ATOM   1037 N N   . CYS   A 1 128 ? -37.09792  -32.51661 -110.42190 1.000 11.50223  ? 128 CYS   A N   1 
ATOM   1038 C CA  . CYS   A 1 128 ? -36.69240  -31.70711 -111.55770 1.000 15.70981  ? 128 CYS   A CA  1 
ATOM   1039 C C   . CYS   A 1 128 ? -35.54799  -30.79483 -111.14842 1.000 14.55016  ? 128 CYS   A C   1 
ATOM   1040 O O   . CYS   A 1 128 ? -35.35002  -30.51338 -109.96361 1.000 16.15811  ? 128 CYS   A O   1 
ATOM   1041 C CB  . CYS   A 1 128 ? -37.86616  -30.88988 -112.10288 1.000 14.14504  ? 128 CYS   A CB  1 
ATOM   1042 S SG  . CYS   A 1 128 ? -38.49715  -29.70724 -110.90865 1.000 16.55030  ? 128 CYS   A SG  1 
ATOM   1043 N N   . TRP   A 1 129 ? -34.82215  -30.30407 -112.15838 1.000 14.03863  ? 129 TRP   A N   1 
ATOM   1044 C CA  . TRP   A 1 129 ? -33.65461  -29.44636 -111.98031 1.000 13.96155  ? 129 TRP   A CA  1 
ATOM   1045 C C   . TRP   A 1 129 ? -33.72186  -28.28251 -112.96209 1.000 19.82974  ? 129 TRP   A C   1 
ATOM   1046 O O   . TRP   A 1 129 ? -33.97470  -28.48221 -114.15748 1.000 18.18595  ? 129 TRP   A O   1 
ATOM   1047 C CB  . TRP   A 1 129 ? -32.34273  -30.22218 -112.22227 1.000 11.62909  ? 129 TRP   A CB  1 
ATOM   1048 C CG  . TRP   A 1 129 ? -31.81489  -30.89205 -111.01079 1.000 15.71489  ? 129 TRP   A CG  1 
ATOM   1049 C CD1 . TRP   A 1 129 ? -31.95196  -32.20865 -110.66813 1.000 12.15157  ? 129 TRP   A CD1 1 
ATOM   1050 C CD2 . TRP   A 1 129 ? -31.07876  -30.27460 -109.95637 1.000 16.90859  ? 129 TRP   A CD2 1 
ATOM   1051 N NE1 . TRP   A 1 129 ? -31.34241  -32.44502 -109.46718 1.000 18.18987  ? 129 TRP   A NE1 1 
ATOM   1052 C CE2 . TRP   A 1 129 ? -30.80658  -31.27210 -109.00104 1.000 15.12351  ? 129 TRP   A CE2 1 
ATOM   1053 C CE3 . TRP   A 1 129 ? -30.63492  -28.96553 -109.71901 1.000 14.42338  ? 129 TRP   A CE3 1 
ATOM   1054 C CZ2 . TRP   A 1 129 ? -30.10312  -31.00572 -107.82268 1.000 14.88201  ? 129 TRP   A CZ2 1 
ATOM   1055 C CZ3 . TRP   A 1 129 ? -29.93937  -28.69780 -108.55224 1.000 15.27455  ? 129 TRP   A CZ3 1 
ATOM   1056 C CH2 . TRP   A 1 129 ? -29.68101  -29.71343 -107.61731 1.000 20.92034  ? 129 TRP   A CH2 1 
ATOM   1057 N N   . ASP   A 1 130 ? -33.50845  -27.07022 -112.45920 1.000 15.99196  ? 130 ASP   A N   1 
ATOM   1058 C CA  . ASP   A 1 130 ? -33.11884  -25.97134 -113.33279 1.000 14.50638  ? 130 ASP   A CA  1 
ATOM   1059 C C   . ASP   A 1 130 ? -31.66654  -26.18876 -113.74319 1.000 18.63167  ? 130 ASP   A C   1 
ATOM   1060 O O   . ASP   A 1 130 ? -30.74347  -25.84151 -112.98938 1.000 16.76823  ? 130 ASP   A O   1 
ATOM   1061 C CB  . ASP   A 1 130 ? -33.29197  -24.62587 -112.62880 1.000 15.61367  ? 130 ASP   A CB  1 
ATOM   1062 C CG  . ASP   A 1 130 ? -34.72346  -24.38949 -112.15186 1.000 17.44809  ? 130 ASP   A CG  1 
ATOM   1063 O OD1 . ASP   A 1 130 ? -35.67508  -24.94850 -112.76601 1.000 11.47193  ? 130 ASP   A OD1 1 
ATOM   1064 O OD2 . ASP   A 1 130 ? -34.88753  -23.63482 -111.16406 1.000 11.93865  ? 130 ASP   A OD2 1 
ATOM   1065 N N   . VAL   A 1 131 ? -31.45238  -26.82303 -114.89910 1.000 12.81549  ? 131 VAL   A N   1 
ATOM   1066 C CA  . VAL   A 1 131 ? -30.08679  -27.11358 -115.33551 1.000 15.46806  ? 131 VAL   A CA  1 
ATOM   1067 C C   . VAL   A 1 131 ? -29.35609  -25.82661 -115.69040 1.000 14.09026  ? 131 VAL   A C   1 
ATOM   1068 O O   . VAL   A 1 131 ? -28.27080  -25.54990 -115.16682 1.000 14.19992  ? 131 VAL   A O   1 
ATOM   1069 C CB  . VAL   A 1 131 ? -30.08796  -28.10767 -116.51346 1.000 18.42867  ? 131 VAL   A CB  1 
ATOM   1070 C CG1 . VAL   A 1 131 ? -28.65602  -28.49876 -116.86881 1.000 18.61209  ? 131 VAL   A CG1 1 
ATOM   1071 C CG2 . VAL   A 1 131 ? -30.89824  -29.35747 -116.15333 1.000 11.45022  ? 131 VAL   A CG2 1 
ATOM   1072 N N   . ILE   A 1 132 ? -29.95505  -25.01909 -116.56998 1.000 17.25832  ? 132 ILE   A N   1 
ATOM   1073 C CA  . ILE   A 1 132 ? -29.39851  -23.75753 -117.04238 1.000 17.45854  ? 132 ILE   A CA  1 
ATOM   1074 C C   . ILE   A 1 132 ? -30.27126  -22.62875 -116.50766 1.000 16.87288  ? 132 ILE   A C   1 
ATOM   1075 O O   . ILE   A 1 132 ? -31.50099  -22.67468 -116.63409 1.000 11.39839  ? 132 ILE   A O   1 
ATOM   1076 C CB  . ILE   A 1 132 ? -29.33312  -23.72066 -118.58368 1.000 20.04185  ? 132 ILE   A CB  1 
ATOM   1077 C CG1 . ILE   A 1 132 ? -28.39924  -24.80716 -119.11600 1.000 16.80122  ? 132 ILE   A CG1 1 
ATOM   1078 C CG2 . ILE   A 1 132 ? -28.89066  -22.35027 -119.07662 1.000 13.42940  ? 132 ILE   A CG2 1 
ATOM   1079 C CD1 . ILE   A 1 132 ? -26.91580  -24.54335 -118.79082 1.000 14.84969  ? 132 ILE   A CD1 1 
ATOM   1080 N N   . ASN   A 1 133 ? -29.64161  -21.61528 -115.92413 1.000 15.73552  ? 133 ASN   A N   1 
ATOM   1081 C CA  . ASN   A 1 133 ? -30.34919  -20.45951 -115.38759 1.000 15.87336  ? 133 ASN   A CA  1 
ATOM   1082 C C   . ASN   A 1 133 ? -29.93750  -19.21696 -116.16552 1.000 19.33470  ? 133 ASN   A C   1 
ATOM   1083 O O   . ASN   A 1 133 ? -28.74499  -18.90286 -116.24516 1.000 17.06968  ? 133 ASN   A O   1 
ATOM   1084 C CB  . ASN   A 1 133 ? -30.05765  -20.27589 -113.89317 1.000 14.74696  ? 133 ASN   A CB  1 
ATOM   1085 C CG  . ASN   A 1 133 ? -31.20867  -19.59080 -113.14467 1.000 19.24537  ? 133 ASN   A CG  1 
ATOM   1086 O OD1 . ASN   A 1 133 ? -32.38147  -19.80707 -113.45501 1.000 21.20452  ? 133 ASN   A OD1 1 
ATOM   1087 N ND2 . ASN   A 1 133 ? -30.87434  -18.76993 -112.15794 1.000 16.14744  ? 133 ASN   A ND2 1 
ATOM   1088 N N   . GLU   A 1 134 ? -30.92190  -18.53039 -116.75939 1.000 19.42493  ? 134 GLU   A N   1 
ATOM   1089 C CA  . GLU   A 1 134 ? -30.74625  -17.15945 -117.24247 1.000 15.23066  ? 134 GLU   A CA  1 
ATOM   1090 C C   . GLU   A 1 134 ? -29.60185  -17.02697 -118.25597 1.000 21.81503  ? 134 GLU   A C   1 
ATOM   1091 O O   . GLU   A 1 134 ? -28.80813  -16.08378 -118.20415 1.000 19.16241  ? 134 GLU   A O   1 
ATOM   1092 C CB  . GLU   A 1 134 ? -30.52245  -16.21308 -116.06528 1.000 14.30960  ? 134 GLU   A CB  1 
ATOM   1093 C CG  . GLU   A 1 134 ? -31.63444  -16.20925 -115.07486 1.000 15.50712  ? 134 GLU   A CG  1 
ATOM   1094 C CD  . GLU   A 1 134 ? -31.26598  -15.48113 -113.80065 1.000 24.14455  ? 134 GLU   A CD  1 
ATOM   1095 O OE1 . GLU   A 1 134 ? -30.19397  -14.83446 -113.75421 1.000 19.90420  ? 134 GLU   A OE1 1 
ATOM   1096 O OE2 . GLU   A 1 134 ? -32.05826  -15.55143 -112.84358 1.000 21.68674  ? 134 GLU   A OE2 1 
ATOM   1097 N N   . ALA   A 1 135 ? -29.51183  -17.97165 -119.18988 1.000 19.99153  ? 135 ALA   A N   1 
ATOM   1098 C CA  . ALA   A 1 135 ? -28.46971  -17.90456 -120.20605 1.000 18.93251  ? 135 ALA   A CA  1 
ATOM   1099 C C   . ALA   A 1 135 ? -28.78360  -16.88636 -121.29714 1.000 24.45163  ? 135 ALA   A C   1 
ATOM   1100 O O   . ALA   A 1 135 ? -27.85602  -16.34889 -121.91854 1.000 20.65730  ? 135 ALA   A O   1 
ATOM   1101 C CB  . ALA   A 1 135 ? -28.26316  -19.28063 -120.83942 1.000 16.33125  ? 135 ALA   A CB  1 
ATOM   1102 N N   . VAL   A 1 136 ? -30.06931  -16.62918 -121.56095 1.000 18.47021  ? 136 VAL   A N   1 
ATOM   1103 C CA  . VAL   A 1 136 ? -30.45723  -15.72147 -122.63472 1.000 21.14677  ? 136 VAL   A CA  1 
ATOM   1104 C C   . VAL   A 1 136 ? -30.13842  -14.27911 -122.23970 1.000 29.07599  ? 136 VAL   A C   1 
ATOM   1105 O O   . VAL   A 1 136 ? -30.25637  -13.89028 -121.06569 1.000 28.42132  ? 136 VAL   A O   1 
ATOM   1106 C CB  . VAL   A 1 136 ? -31.95047  -15.90733 -122.95781 1.000 17.90555  ? 136 VAL   A CB  1 
ATOM   1107 C CG1 . VAL   A 1 136 ? -32.50668  -14.68740 -123.65565 1.000 19.33604  ? 136 VAL   A CG1 1 
ATOM   1108 C CG2 . VAL   A 1 136 ? -32.17910  -17.17807 -123.78240 1.000 14.87834  ? 136 VAL   A CG2 1 
ATOM   1109 N N   . ALA   A 1 137 ? -29.71864  -13.47542 -123.21695 1.000 26.09302  ? 137 ALA   A N   1 
ATOM   1110 C CA  . ALA   A 1 137 ? -29.43670  -12.06917 -122.95439 1.000 30.54898  ? 137 ALA   A CA  1 
ATOM   1111 C C   . ALA   A 1 137 ? -30.70986  -11.32119 -122.58481 1.000 26.87398  ? 137 ALA   A C   1 
ATOM   1112 O O   . ALA   A 1 137 ? -31.75576  -11.50041 -123.21064 1.000 26.37990  ? 137 ALA   A O   1 
ATOM   1113 C CB  . ALA   A 1 137 ? -28.79274  -11.41124 -124.17025 1.000 20.65402  ? 137 ALA   A CB  1 
ATOM   1114 N N   . ASP   A 1 138 ? -30.60682  -10.47182 -121.56079 1.000 26.54286  ? 138 ASP   A N   1 
ATOM   1115 C CA  . ASP   A 1 138 ? -31.73571  -9.67866  -121.08763 1.000 38.22636  ? 138 ASP   A CA  1 
ATOM   1116 C C   . ASP   A 1 138 ? -31.91959  -8.39082  -121.87872 1.000 40.24946  ? 138 ASP   A C   1 
ATOM   1117 O O   . ASP   A 1 138 ? -33.00442  -7.80616  -121.84232 1.000 41.62203  ? 138 ASP   A O   1 
ATOM   1118 C CB  . ASP   A 1 138 ? -31.55519  -9.35001  -119.60194 1.000 33.31801  ? 138 ASP   A CB  1 
ATOM   1119 C CG  . ASP   A 1 138 ? -32.84646  -8.92497  -118.93340 1.000 39.88941  ? 138 ASP   A CG  1 
ATOM   1120 O OD1 . ASP   A 1 138 ? -33.89129  -9.56676  -119.16929 1.000 35.50001  ? 138 ASP   A OD1 1 
ATOM   1121 O OD2 . ASP   A 1 138 ? -32.81366  -7.95312  -118.15453 1.000 50.38816  ? 138 ASP   A OD2 1 
ATOM   1122 N N   . GLU   A 1 139 ? -30.89344  -7.94535  -122.59812 1.000 52.37831  ? 139 GLU   A N   1 
ATOM   1123 C CA  . GLU   A 1 139 ? -30.96362  -6.72817  -123.39424 1.000 48.26777  ? 139 GLU   A CA  1 
ATOM   1124 C C   . GLU   A 1 139 ? -30.09661  -6.91052  -124.62679 1.000 47.36988  ? 139 GLU   A C   1 
ATOM   1125 O O   . GLU   A 1 139 ? -29.27571  -7.82597  -124.70393 1.000 45.73630  ? 139 GLU   A O   1 
ATOM   1126 C CB  . GLU   A 1 139 ? -30.50009  -5.50424  -122.59794 1.000 59.52335  ? 139 GLU   A CB  1 
ATOM   1127 C CG  . GLU   A 1 139 ? -29.13110  -5.68917  -121.93000 1.000 67.96810  ? 139 GLU   A CG  1 
ATOM   1128 C CD  . GLU   A 1 139 ? -29.04185  -5.01319  -120.56408 1.000 93.05313  ? 139 GLU   A CD  1 
ATOM   1129 O OE1 . GLU   A 1 139 ? -28.61949  -3.83576  -120.50396 1.000 91.46987  ? 139 GLU   A OE1 1 
ATOM   1130 O OE2 . GLU   A 1 139 ? -29.40035  -5.65902  -119.55119 1.000 87.48291  ? 139 GLU   A OE2 1 
ATOM   1131 N N   . GLY   A 1 140 ? -30.26246  -6.00924  -125.58176 1.000 53.81399  ? 140 GLY   A N   1 
ATOM   1132 C CA  . GLY   A 1 140 ? -29.51677  -6.10374  -126.81389 1.000 36.82349  ? 140 GLY   A CA  1 
ATOM   1133 C C   . GLY   A 1 140 ? -30.13524  -7.12390  -127.74469 1.000 53.01536  ? 140 GLY   A C   1 
ATOM   1134 O O   . GLY   A 1 140 ? -31.25886  -7.59910  -127.54804 1.000 57.07988  ? 140 GLY   A O   1 
ATOM   1135 N N   . ASN   A 1 141 ? -29.38011  -7.46634  -128.78502 1.000 48.50535  ? 141 ASN   A N   1 
ATOM   1136 C CA  . ASN   A 1 141 ? -29.88392  -8.37407  -129.80104 1.000 52.65778  ? 141 ASN   A CA  1 
ATOM   1137 C C   . ASN   A 1 141 ? -29.06392  -9.64365  -129.93198 1.000 53.66616  ? 141 ASN   A C   1 
ATOM   1138 O O   . ASN   A 1 141 ? -29.37829  -10.47860 -130.78897 1.000 53.93300  ? 141 ASN   A O   1 
ATOM   1139 C CB  . ASN   A 1 141 ? -29.97572  -7.66166  -131.15680 1.000 60.93755  ? 141 ASN   A CB  1 
ATOM   1140 C CG  . ASN   A 1 141 ? -30.66993  -6.31703  -131.05356 1.000 74.00595  ? 141 ASN   A CG  1 
ATOM   1141 O OD1 . ASN   A 1 141 ? -30.07820  -5.27444  -131.34172 1.000 82.91581  ? 141 ASN   A OD1 1 
ATOM   1142 N ND2 . ASN   A 1 141 ? -31.92841  -6.33245  -130.61340 1.000 76.57786  ? 141 ASN   A ND2 1 
ATOM   1143 N N   . GLU   A 1 142 ? -28.03047  -9.81792  -129.11623 1.000 47.05681  ? 142 GLU   A N   1 
ATOM   1144 C CA  . GLU   A 1 142 ? -27.39638  -11.12087 -129.01303 1.000 54.62351  ? 142 GLU   A CA  1 
ATOM   1145 C C   . GLU   A 1 142 ? -28.34619  -12.09810 -128.33831 1.000 37.93770  ? 142 GLU   A C   1 
ATOM   1146 O O   . GLU   A 1 142 ? -29.13297  -11.72229 -127.47045 1.000 38.79789  ? 142 GLU   A O   1 
ATOM   1147 C CB  . GLU   A 1 142 ? -26.10238  -11.01994 -128.22068 1.000 53.43485  ? 142 GLU   A CB  1 
ATOM   1148 C CG  . GLU   A 1 142 ? -25.22611  -9.89592  -128.68386 1.000 60.85940  ? 142 GLU   A CG  1 
ATOM   1149 C CD  . GLU   A 1 142 ? -23.95127  -10.40703 -129.29696 1.000 92.46462  ? 142 GLU   A CD  1 
ATOM   1150 O OE1 . GLU   A 1 142 ? -23.85907  -11.63927 -129.51097 1.000 93.84644  ? 142 GLU   A OE1 1 
ATOM   1151 O OE2 . GLU   A 1 142 ? -23.04791  -9.58514  -129.56363 1.000 100.61561 ? 142 GLU   A OE2 1 
ATOM   1152 N N   . LEU   A 1 143 ? -28.28520  -13.36267 -128.76201 1.000 35.72962  ? 143 LEU   A N   1 
ATOM   1153 C CA  . LEU   A 1 143 ? -29.16494  -14.36784 -128.17599 1.000 28.54216  ? 143 LEU   A CA  1 
ATOM   1154 C C   . LEU   A 1 143 ? -28.77272  -14.67775 -126.73880 1.000 32.81839  ? 143 LEU   A C   1 
ATOM   1155 O O   . LEU   A 1 143 ? -29.63779  -14.82620 -125.86871 1.000 34.82623  ? 143 LEU   A O   1 
ATOM   1156 C CB  . LEU   A 1 143 ? -29.14236  -15.64202 -129.01116 1.000 31.21167  ? 143 LEU   A CB  1 
ATOM   1157 C CG  . LEU   A 1 143 ? -30.04492  -16.75272 -128.46621 1.000 37.00105  ? 143 LEU   A CG  1 
ATOM   1158 C CD1 . LEU   A 1 143 ? -31.51724  -16.46065 -128.72227 1.000 29.90628  ? 143 LEU   A CD1 1 
ATOM   1159 C CD2 . LEU   A 1 143 ? -29.65880  -18.10479 -129.04531 1.000 36.93419  ? 143 LEU   A CD2 1 
ATOM   1160 N N   . LEU   A 1 144 ? -27.47894  -14.76158 -126.46954 1.000 30.11994  ? 144 LEU   A N   1 
ATOM   1161 C CA  . LEU   A 1 144 ? -26.96934  -15.24280 -125.19930 1.000 29.25571  ? 144 LEU   A CA  1 
ATOM   1162 C C   . LEU   A 1 144 ? -26.24040  -14.13638 -124.46707 1.000 32.47027  ? 144 LEU   A C   1 
ATOM   1163 O O   . LEU   A 1 144 ? -25.50173  -13.34616 -125.06389 1.000 32.36448  ? 144 LEU   A O   1 
ATOM   1164 C CB  . LEU   A 1 144 ? -26.01769  -16.43954 -125.37494 1.000 19.85750  ? 144 LEU   A CB  1 
ATOM   1165 C CG  . LEU   A 1 144 ? -26.64602  -17.67351 -126.03984 1.000 28.42988  ? 144 LEU   A CG  1 
ATOM   1166 C CD1 . LEU   A 1 144 ? -25.61263  -18.77466 -126.19323 1.000 28.02088  ? 144 LEU   A CD1 1 
ATOM   1167 C CD2 . LEU   A 1 144 ? -27.89690  -18.17739 -125.27840 1.000 24.55550  ? 144 LEU   A CD2 1 
ATOM   1168 N N   . ARG   A 1 145 ? -26.48167  -14.09909 -123.16948 1.000 31.41881  ? 145 ARG   A N   1 
ATOM   1169 C CA  . ARG   A 1 145 ? -25.69958  -13.31464 -122.24382 1.000 27.34995  ? 145 ARG   A CA  1 
ATOM   1170 C C   . ARG   A 1 145 ? -24.24346  -13.78201 -122.28967 1.000 32.15758  ? 145 ARG   A C   1 
ATOM   1171 O O   . ARG   A 1 145 ? -23.97108  -14.94570 -122.60162 1.000 35.27188  ? 145 ARG   A O   1 
ATOM   1172 C CB  . ARG   A 1 145 ? -26.32095  -13.49663 -120.85828 1.000 28.48913  ? 145 ARG   A CB  1 
ATOM   1173 C CG  . ARG   A 1 145 ? -25.60893  -12.94551 -119.68418 1.000 43.20621  ? 145 ARG   A CG  1 
ATOM   1174 C CD  . ARG   A 1 145 ? -26.13695  -13.62454 -118.43222 1.000 30.80584  ? 145 ARG   A CD  1 
ATOM   1175 N NE  . ARG   A 1 145 ? -27.58423  -13.49158 -118.25864 1.000 21.72939  ? 145 ARG   A NE  1 
ATOM   1176 C CZ  . ARG   A 1 145 ? -28.17324  -12.39706 -117.77936 1.000 23.85883  ? 145 ARG   A CZ  1 
ATOM   1177 N NH1 . ARG   A 1 145 ? -27.44665  -11.33550 -117.47021 1.000 23.89040  ? 145 ARG   A NH1 1 
ATOM   1178 N NH2 . ARG   A 1 145 ? -29.48820  -12.34785 -117.63005 1.000 25.95651  ? 145 ARG   A NH2 1 
ATOM   1179 N N   . PRO   A 1 146 ? -23.28130  -12.89368 -122.03493 1.000 43.91987  ? 146 PRO   A N   1 
ATOM   1180 C CA  . PRO   A 1 146 ? -21.89987  -13.35860 -121.83853 1.000 36.48670  ? 146 PRO   A CA  1 
ATOM   1181 C C   . PRO   A 1 146 ? -21.76125  -14.02012 -120.47895 1.000 40.51838  ? 146 PRO   A C   1 
ATOM   1182 O O   . PRO   A 1 146 ? -22.42671  -13.64293 -119.50925 1.000 39.05706  ? 146 PRO   A O   1 
ATOM   1183 C CB  . PRO   A 1 146 ? -21.05700  -12.07712 -121.91313 1.000 28.89973  ? 146 PRO   A CB  1 
ATOM   1184 C CG  . PRO   A 1 146 ? -22.00863  -10.96358 -122.28003 1.000 35.52947  ? 146 PRO   A CG  1 
ATOM   1185 C CD  . PRO   A 1 146 ? -23.39502  -11.42716 -121.94345 1.000 35.55668  ? 146 PRO   A CD  1 
ATOM   1186 N N   . SER   A 1 147 ? -20.89444  -15.02708 -120.41794 1.000 29.42514  ? 147 SER   A N   1 
ATOM   1187 C CA  . SER   A 1 147 ? -20.61242  -15.71189 -119.16470 1.000 31.70958  ? 147 SER   A CA  1 
ATOM   1188 C C   . SER   A 1 147 ? -19.36217  -16.54321 -119.35965 1.000 35.32031  ? 147 SER   A C   1 
ATOM   1189 O O   . SER   A 1 147 ? -19.03641  -16.95241 -120.47886 1.000 37.14387  ? 147 SER   A O   1 
ATOM   1190 C CB  . SER   A 1 147 ? -21.76969  -16.61078 -118.71159 1.000 24.51384  ? 147 SER   A CB  1 
ATOM   1191 O OG  . SER   A 1 147 ? -21.70633  -17.87515 -119.34892 1.000 22.08499  ? 147 SER   A OG  1 
ATOM   1192 N N   . LYS   A 1 148 ? -18.67919  -16.81184 -118.24658 1.000 29.04269  ? 148 LYS   A N   1 
ATOM   1193 C CA  . LYS   A 1 148 ? -17.46228  -17.60528 -118.33101 1.000 27.35489  ? 148 LYS   A CA  1 
ATOM   1194 C C   . LYS   A 1 148 ? -17.75548  -19.02696 -118.79959 1.000 28.97490  ? 148 LYS   A C   1 
ATOM   1195 O O   . LYS   A 1 148 ? -16.93910  -19.61758 -119.51125 1.000 28.24164  ? 148 LYS   A O   1 
ATOM   1196 C CB  . LYS   A 1 148 ? -16.74005  -17.58824 -116.98942 1.000 23.63661  ? 148 LYS   A CB  1 
ATOM   1197 C CG  . LYS   A 1 148 ? -16.27895  -16.18191 -116.56629 1.000 24.49895  ? 148 LYS   A CG  1 
ATOM   1198 C CD  . LYS   A 1 148 ? -15.70938  -16.20204 -115.15712 1.000 41.60648  ? 148 LYS   A CD  1 
ATOM   1199 C CE  . LYS   A 1 148 ? -15.49911  -14.80695 -114.57880 1.000 51.02132  ? 148 LYS   A CE  1 
ATOM   1200 N NZ  . LYS   A 1 148 ? -15.33973  -14.84998 -113.08487 1.000 45.37218  ? 148 LYS   A NZ  1 
ATOM   1201 N N   . TRP   A 1 149 ? -18.91687  -19.58391 -118.43982 1.000 21.35928  ? 149 TRP   A N   1 
ATOM   1202 C CA  . TRP   A 1 149 ? -19.31875  -20.86563 -119.00846 1.000 22.85898  ? 149 TRP   A CA  1 
ATOM   1203 C C   . TRP   A 1 149 ? -19.30672  -20.79580 -120.52722 1.000 26.05911  ? 149 TRP   A C   1 
ATOM   1204 O O   . TRP   A 1 149 ? -18.72608  -21.65021 -121.20221 1.000 22.80610  ? 149 TRP   A O   1 
ATOM   1205 C CB  . TRP   A 1 149 ? -20.72495  -21.26487 -118.53337 1.000 21.20950  ? 149 TRP   A CB  1 
ATOM   1206 C CG  . TRP   A 1 149 ? -20.89691  -21.51349 -117.05480 1.000 26.57564  ? 149 TRP   A CG  1 
ATOM   1207 C CD1 . TRP   A 1 149 ? -21.53373  -20.70120 -116.15461 1.000 22.30136  ? 149 TRP   A CD1 1 
ATOM   1208 C CD2 . TRP   A 1 149 ? -20.46444  -22.66311 -116.31533 1.000 20.46737  ? 149 TRP   A CD2 1 
ATOM   1209 N NE1 . TRP   A 1 149 ? -21.51555  -21.27140 -114.90310 1.000 19.96680  ? 149 TRP   A NE1 1 
ATOM   1210 C CE2 . TRP   A 1 149 ? -20.86635  -22.47413 -114.97381 1.000 20.53298  ? 149 TRP   A CE2 1 
ATOM   1211 C CE3 . TRP   A 1 149 ? -19.77692  -23.83292 -116.65444 1.000 17.40126  ? 149 TRP   A CE3 1 
ATOM   1212 C CZ2 . TRP   A 1 149 ? -20.59373  -23.40696 -113.97121 1.000 23.11423  ? 149 TRP   A CZ2 1 
ATOM   1213 C CZ3 . TRP   A 1 149 ? -19.50398  -24.75526 -115.65421 1.000 18.65707  ? 149 TRP   A CZ3 1 
ATOM   1214 C CH2 . TRP   A 1 149 ? -19.91349  -24.53753 -114.33047 1.000 15.79814  ? 149 TRP   A CH2 1 
ATOM   1215 N N   . ARG   A 1 150 ? -19.96592  -19.77983 -121.07699 1.000 29.17316  ? 150 ARG   A N   1 
ATOM   1216 C CA  . ARG   A 1 150 ? -20.09900  -19.65443 -122.51998 1.000 29.91771  ? 150 ARG   A CA  1 
ATOM   1217 C C   . ARG   A 1 150 ? -18.77261  -19.27663 -123.16122 1.000 31.02064  ? 150 ARG   A C   1 
ATOM   1218 O O   . ARG   A 1 150 ? -18.38588  -19.83930 -124.19206 1.000 26.80932  ? 150 ARG   A O   1 
ATOM   1219 C CB  . ARG   A 1 150 ? -21.16280  -18.60851 -122.81869 1.000 33.99857  ? 150 ARG   A CB  1 
ATOM   1220 C CG  . ARG   A 1 150 ? -21.36804  -18.34709 -124.27471 1.000 30.72446  ? 150 ARG   A CG  1 
ATOM   1221 C CD  . ARG   A 1 150 ? -22.13882  -17.06422 -124.45619 1.000 23.68630  ? 150 ARG   A CD  1 
ATOM   1222 N NE  . ARG   A 1 150 ? -22.22944  -16.73830 -125.87026 1.000 40.28198  ? 150 ARG   A NE  1 
ATOM   1223 C CZ  . ARG   A 1 150 ? -22.50244  -15.52963 -126.33724 1.000 37.54709  ? 150 ARG   A CZ  1 
ATOM   1224 N NH1 . ARG   A 1 150 ? -22.72239  -14.52751 -125.48948 1.000 29.51933  ? 150 ARG   A NH1 1 
ATOM   1225 N NH2 . ARG   A 1 150 ? -22.56881  -15.33561 -127.65025 1.000 43.30180  ? 150 ARG   A NH2 1 
ATOM   1226 N N   . GLN   A 1 151 ? -18.07019  -18.32387 -122.54481 1.000 32.24812  ? 151 GLN   A N   1 
ATOM   1227 C CA  . GLN   A 1 151 ? -16.74675  -17.89048 -122.97848 1.000 30.66897  ? 151 GLN   A CA  1 
ATOM   1228 C C   . GLN   A 1 151 ? -15.79756  -19.06605 -123.17169 1.000 34.27726  ? 151 GLN   A C   1 
ATOM   1229 O O   . GLN   A 1 151 ? -15.14568  -19.19450 -124.21151 1.000 31.61469  ? 151 GLN   A O   1 
ATOM   1230 C CB  . GLN   A 1 151 ? -16.19504  -16.93060 -121.92398 1.000 36.56823  ? 151 GLN   A CB  1 
ATOM   1231 C CG  . GLN   A 1 151 ? -15.23851  -15.86216 -122.38247 1.000 47.20029  ? 151 GLN   A CG  1 
ATOM   1232 C CD  . GLN   A 1 151 ? -14.35965  -15.39514 -121.23305 1.000 58.15631  ? 151 GLN   A CD  1 
ATOM   1233 O OE1 . GLN   A 1 151 ? -13.33711  -16.01475 -120.92712 1.000 60.40764  ? 151 GLN   A OE1 1 
ATOM   1234 N NE2 . GLN   A 1 151 ? -14.78524  -14.33256 -120.55333 1.000 56.95589  ? 151 GLN   A NE2 1 
ATOM   1235 N N   . ILE   A 1 152 ? -15.70591  -19.93367 -122.16708 1.000 31.49686  ? 152 ILE   A N   1 
ATOM   1236 C CA  . ILE   A 1 152 ? -14.68088  -20.96496 -122.16660 1.000 24.15576  ? 152 ILE   A CA  1 
ATOM   1237 C C   . ILE   A 1 152 ? -15.11531  -22.17398 -122.98646 1.000 33.99335  ? 152 ILE   A C   1 
ATOM   1238 O O   . ILE   A 1 152 ? -14.32575  -22.72705 -123.76028 1.000 34.19600  ? 152 ILE   A O   1 
ATOM   1239 C CB  . ILE   A 1 152 ? -14.33980  -21.34452 -120.71673 1.000 23.66712  ? 152 ILE   A CB  1 
ATOM   1240 C CG1 . ILE   A 1 152 ? -13.70990  -20.14749 -119.99681 1.000 25.32195  ? 152 ILE   A CG1 1 
ATOM   1241 C CG2 . ILE   A 1 152 ? -13.42454  -22.53828 -120.69463 1.000 25.77675  ? 152 ILE   A CG2 1 
ATOM   1242 C CD1 . ILE   A 1 152 ? -13.34280  -20.40301 -118.54918 1.000 26.85650  ? 152 ILE   A CD1 1 
ATOM   1243 N N   . ILE   A 1 153 ? -16.36716  -22.60812 -122.84310 1.000 24.33060  ? 153 ILE   A N   1 
ATOM   1244 C CA  . ILE   A 1 153 ? -16.78293  -23.82972 -123.52220 1.000 23.33303  ? 153 ILE   A CA  1 
ATOM   1245 C C   . ILE   A 1 153 ? -17.20988  -23.54772 -124.95526 1.000 30.56721  ? 153 ILE   A C   1 
ATOM   1246 O O   . ILE   A 1 153 ? -16.98870  -24.36718 -125.85475 1.000 30.16262  ? 153 ILE   A O   1 
ATOM   1247 C CB  . ILE   A 1 153 ? -17.90100  -24.52808 -122.72491 1.000 25.62560  ? 153 ILE   A CB  1 
ATOM   1248 C CG1 . ILE   A 1 153 ? -17.33781  -25.14046 -121.44469 1.000 25.44940  ? 153 ILE   A CG1 1 
ATOM   1249 C CG2 . ILE   A 1 153 ? -18.55482  -25.62416 -123.54000 1.000 18.48729  ? 153 ILE   A CG2 1 
ATOM   1250 C CD1 . ILE   A 1 153 ? -18.41087  -25.63675 -120.51667 1.000 27.76887  ? 153 ILE   A CD1 1 
ATOM   1251 N N   . GLY   A 1 154 ? -17.83078  -22.40527 -125.19329 1.000 31.44175  ? 154 GLY   A N   1 
ATOM   1252 C CA  . GLY   A 1 154 ? -18.54263  -22.16656 -126.43146 1.000 22.03314  ? 154 GLY   A CA  1 
ATOM   1253 C C   . GLY   A 1 154 ? -20.04542  -22.26422 -126.23101 1.000 29.84132  ? 154 GLY   A C   1 
ATOM   1254 O O   . GLY   A 1 154 ? -20.54777  -22.52405 -125.13580 1.000 29.60478  ? 154 GLY   A O   1 
ATOM   1255 N N   . ASP   A 1 155 ? -20.76574  -22.06527 -127.33269 1.000 33.57822  ? 155 ASP   A N   1 
ATOM   1256 C CA  . ASP   A 1 155 ? -22.21049  -21.89793 -127.24235 1.000 27.61009  ? 155 ASP   A CA  1 
ATOM   1257 C C   . ASP   A 1 155 ? -22.96296  -23.20277 -126.99825 1.000 30.86681  ? 155 ASP   A C   1 
ATOM   1258 O O   . ASP   A 1 155 ? -24.16522  -23.15767 -126.71995 1.000 37.41434  ? 155 ASP   A O   1 
ATOM   1259 C CB  . ASP   A 1 155 ? -22.73946  -21.21483 -128.50975 1.000 30.30324  ? 155 ASP   A CB  1 
ATOM   1260 C CG  . ASP   A 1 155 ? -22.42793  -19.71549 -128.54466 1.000 39.60922  ? 155 ASP   A CG  1 
ATOM   1261 O OD1 . ASP   A 1 155 ? -22.16215  -19.11493 -127.47591 1.000 34.55385  ? 155 ASP   A OD1 1 
ATOM   1262 O OD2 . ASP   A 1 155 ? -22.46374  -19.12945 -129.64636 1.000 54.33211  ? 155 ASP   A OD2 1 
ATOM   1263 N N   . ASP   A 1 156 ? -22.30434  -24.35331 -127.08346 1.000 27.22906  ? 156 ASP   A N   1 
ATOM   1264 C CA  . ASP   A 1 156 ? -22.95393  -25.62777 -126.81092 1.000 27.01783  ? 156 ASP   A CA  1 
ATOM   1265 C C   . ASP   A 1 156 ? -22.82275  -26.05845 -125.34990 1.000 30.50167  ? 156 ASP   A C   1 
ATOM   1266 O O   . ASP   A 1 156 ? -23.12472  -27.21363 -125.03059 1.000 31.97425  ? 156 ASP   A O   1 
ATOM   1267 C CB  . ASP   A 1 156 ? -22.37465  -26.71359 -127.71523 1.000 22.44447  ? 156 ASP   A CB  1 
ATOM   1268 C CG  . ASP   A 1 156 ? -20.92676  -27.03053 -127.37092 1.000 26.06237  ? 156 ASP   A CG  1 
ATOM   1269 O OD1 . ASP   A 1 156 ? -20.21443  -26.08945 -126.96723 1.000 34.56250  ? 156 ASP   A OD1 1 
ATOM   1270 O OD2 . ASP   A 1 156 ? -20.50775  -28.20502 -127.47139 1.000 30.55165  ? 156 ASP   A OD2 1 
ATOM   1271 N N   . PHE   A 1 157 ? -22.36105  -25.17129 -124.46063 1.000 23.83957  ? 157 PHE   A N   1 
ATOM   1272 C CA  . PHE   A 1 157 ? -22.27618  -25.53529 -123.04957 1.000 18.27333  ? 157 PHE   A CA  1 
ATOM   1273 C C   . PHE   A 1 157 ? -23.63730  -25.93407 -122.48340 1.000 26.07285  ? 157 PHE   A C   1 
ATOM   1274 O O   . PHE   A 1 157 ? -23.71585  -26.82318 -121.62733 1.000 28.10374  ? 157 PHE   A O   1 
ATOM   1275 C CB  . PHE   A 1 157 ? -21.66389  -24.39187 -122.23620 1.000 21.03264  ? 157 PHE   A CB  1 
ATOM   1276 C CG  . PHE   A 1 157 ? -22.59374  -23.22616 -121.97859 1.000 24.60952  ? 157 PHE   A CG  1 
ATOM   1277 C CD1 . PHE   A 1 157 ? -22.81405  -22.26042 -122.95577 1.000 21.88045  ? 157 PHE   A CD1 1 
ATOM   1278 C CD2 . PHE   A 1 157 ? -23.20609  -23.06578 -120.73205 1.000 27.18385  ? 157 PHE   A CD2 1 
ATOM   1279 C CE1 . PHE   A 1 157 ? -23.64972  -21.16939 -122.71586 1.000 19.01939  ? 157 PHE   A CE1 1 
ATOM   1280 C CE2 . PHE   A 1 157 ? -24.05356  -21.97600 -120.47691 1.000 24.92002  ? 157 PHE   A CE2 1 
ATOM   1281 C CZ  . PHE   A 1 157 ? -24.27659  -21.02467 -121.47076 1.000 25.25300  ? 157 PHE   A CZ  1 
ATOM   1282 N N   . MET   A 1 158 ? -24.72019  -25.31473 -122.95911 1.000 23.51473  ? 158 MET   A N   1 
ATOM   1283 C CA  . MET   A 1 158 ? -26.03641  -25.67872 -122.45484 1.000 23.06759  ? 158 MET   A CA  1 
ATOM   1284 C C   . MET   A 1 158 ? -26.40972  -27.09404 -122.86827 1.000 23.73911  ? 158 MET   A C   1 
ATOM   1285 O O   . MET   A 1 158 ? -26.95030  -27.85360 -122.05411 1.000 22.45494  ? 158 MET   A O   1 
ATOM   1286 C CB  . MET   A 1 158 ? -27.08134  -24.67517 -122.93372 1.000 24.87044  ? 158 MET   A CB  1 
ATOM   1287 C CG  . MET   A 1 158 ? -26.91680  -23.28908 -122.31040 1.000 28.96208  ? 158 MET   A CG  1 
ATOM   1288 S SD  . MET   A 1 158 ? -28.06632  -22.08442 -123.02034 1.000 26.34809  ? 158 MET   A SD  1 
ATOM   1289 C CE  . MET   A 1 158 ? -27.29225  -21.79999 -124.62182 1.000 21.46845  ? 158 MET   A CE  1 
ATOM   1290 N N   . GLU   A 1 159 ? -26.13215  -27.46124 -124.12705 1.000 23.54270  ? 159 GLU   A N   1 
ATOM   1291 C CA  . GLU   A 1 159 ? -26.32204  -28.84005 -124.58348 1.000 30.61775  ? 159 GLU   A CA  1 
ATOM   1292 C C   . GLU   A 1 159 ? -25.61874  -29.82107 -123.66011 1.000 25.03750  ? 159 GLU   A C   1 
ATOM   1293 O O   . GLU   A 1 159 ? -26.21114  -30.79972 -123.19193 1.000 20.51805  ? 159 GLU   A O   1 
ATOM   1294 C CB  . GLU   A 1 159 ? -25.76540  -29.01750 -125.99435 1.000 18.58646  ? 159 GLU   A CB  1 
ATOM   1295 C CG  . GLU   A 1 159 ? -26.63614  -28.52784 -127.08856 1.000 34.18361  ? 159 GLU   A CG  1 
ATOM   1296 C CD  . GLU   A 1 159 ? -25.89070  -28.45765 -128.40232 1.000 40.24421  ? 159 GLU   A CD  1 
ATOM   1297 O OE1 . GLU   A 1 159 ? -25.87635  -27.35950 -129.01972 1.000 33.41341  ? 159 GLU   A OE1 1 
ATOM   1298 O OE2 . GLU   A 1 159 ? -25.30558  -29.50010 -128.78669 1.000 30.32382  ? 159 GLU   A OE2 1 
ATOM   1299 N N   . GLN   A 1 160 ? -24.33538  -29.57176 -123.41366 1.000 20.81482  ? 160 GLN   A N   1 
ATOM   1300 C CA  . GLN   A 1 160 ? -23.55150  -30.42651 -122.53662 1.000 22.97619  ? 160 GLN   A CA  1 
ATOM   1301 C C   . GLN   A 1 160 ? -24.18487  -30.53614 -121.15724 1.000 23.92860  ? 160 GLN   A C   1 
ATOM   1302 O O   . GLN   A 1 160 ? -24.32175  -31.63786 -120.61614 1.000 22.98559  ? 160 GLN   A O   1 
ATOM   1303 C CB  . GLN   A 1 160 ? -22.12819  -29.88405 -122.44040 1.000 20.75843  ? 160 GLN   A CB  1 
ATOM   1304 C CG  . GLN   A 1 160 ? -21.36144  -29.98687 -123.74512 1.000 28.56029  ? 160 GLN   A CG  1 
ATOM   1305 C CD  . GLN   A 1 160 ? -21.45308  -31.37654 -124.36290 1.000 34.26815  ? 160 GLN   A CD  1 
ATOM   1306 O OE1 . GLN   A 1 160 ? -21.03904  -32.37015 -123.75647 1.000 43.55565  ? 160 GLN   A OE1 1 
ATOM   1307 N NE2 . GLN   A 1 160 ? -22.00731  -31.45254 -125.57245 1.000 33.64640  ? 160 GLN   A NE2 1 
ATOM   1308 N N   . ALA   A 1 161 ? -24.59131  -29.40370 -120.57412 1.000 23.06482  ? 161 ALA   A N   1 
ATOM   1309 C CA  . ALA   A 1 161 ? -25.09821  -29.43336 -119.20434 1.000 20.84154  ? 161 ALA   A CA  1 
ATOM   1310 C C   . ALA   A 1 161 ? -26.33368  -30.32024 -119.09739 1.000 17.83239  ? 161 ALA   A C   1 
ATOM   1311 O O   . ALA   A 1 161 ? -26.40988  -31.18391 -118.21805 1.000 17.87894  ? 161 ALA   A O   1 
ATOM   1312 C CB  . ALA   A 1 161 ? -25.39773  -28.01609 -118.71476 1.000 21.99395  ? 161 ALA   A CB  1 
ATOM   1313 N N   . PHE   A 1 162 ? -27.29812  -30.13775 -120.00809 1.000 15.84183  ? 162 PHE   A N   1 
ATOM   1314 C CA  . PHE   A 1 162 ? -28.49579  -30.97307 -120.02213 1.000 18.95249  ? 162 PHE   A CA  1 
ATOM   1315 C C   . PHE   A 1 162 ? -28.14737  -32.45367 -120.17199 1.000 22.73647  ? 162 PHE   A C   1 
ATOM   1316 O O   . PHE   A 1 162 ? -28.69107  -33.30530 -119.45485 1.000 20.40281  ? 162 PHE   A O   1 
ATOM   1317 C CB  . PHE   A 1 162 ? -29.43577  -30.51996 -121.14844 1.000 18.68663  ? 162 PHE   A CB  1 
ATOM   1318 C CG  . PHE   A 1 162 ? -30.31773  -29.35954 -120.76435 1.000 14.52473  ? 162 PHE   A CG  1 
ATOM   1319 C CD1 . PHE   A 1 162 ? -31.43406  -29.55558 -119.96903 1.000 12.73484  ? 162 PHE   A CD1 1 
ATOM   1320 C CD2 . PHE   A 1 162 ? -30.00231  -28.06368 -121.16123 1.000 21.40496  ? 162 PHE   A CD2 1 
ATOM   1321 C CE1 . PHE   A 1 162 ? -32.22864  -28.49474 -119.58781 1.000 13.13687  ? 162 PHE   A CE1 1 
ATOM   1322 C CE2 . PHE   A 1 162 ? -30.80153  -26.99240 -120.79187 1.000 14.53628  ? 162 PHE   A CE2 1 
ATOM   1323 C CZ  . PHE   A 1 162 ? -31.91485  -27.20887 -120.00185 1.000 14.10409  ? 162 PHE   A CZ  1 
ATOM   1324 N N   . LEU   A 1 163 ? -27.23385  -32.77830 -121.09036 1.000 18.51165  ? 163 LEU   A N   1 
ATOM   1325 C CA  . LEU   A 1 163 ? -26.85501  -34.17335 -121.29798 1.000 23.90164  ? 163 LEU   A CA  1 
ATOM   1326 C C   . LEU   A 1 163 ? -26.18768  -34.75393 -120.05583 1.000 20.31583  ? 163 LEU   A C   1 
ATOM   1327 O O   . LEU   A 1 163 ? -26.46921  -35.89348 -119.66631 1.000 19.07644  ? 163 LEU   A O   1 
ATOM   1328 C CB  . LEU   A 1 163 ? -25.93137  -34.29201 -122.51418 1.000 25.38394  ? 163 LEU   A CB  1 
ATOM   1329 C CG  . LEU   A 1 163 ? -26.56584  -34.04447 -123.88892 1.000 27.12486  ? 163 LEU   A CG  1 
ATOM   1330 C CD1 . LEU   A 1 163 ? -25.48241  -33.78965 -124.93007 1.000 15.17324  ? 163 LEU   A CD1 1 
ATOM   1331 C CD2 . LEU   A 1 163 ? -27.47916  -35.20413 -124.33462 1.000 15.19760  ? 163 LEU   A CD2 1 
ATOM   1332 N N   . TYR   A 1 164 ? -25.31380  -33.97947 -119.41031 1.000 16.27227  ? 164 TYR   A N   1 
ATOM   1333 C CA  . TYR   A 1 164 ? -24.73937  -34.41661 -118.14246 1.000 17.61120  ? 164 TYR   A CA  1 
ATOM   1334 C C   . TYR   A 1 164 ? -25.82506  -34.65360 -117.09028 1.000 18.75003  ? 164 TYR   A C   1 
ATOM   1335 O O   . TYR   A 1 164 ? -25.78454  -35.64533 -116.34971 1.000 19.12584  ? 164 TYR   A O   1 
ATOM   1336 C CB  . TYR   A 1 164 ? -23.72607  -33.38234 -117.64976 1.000 17.32169  ? 164 TYR   A CB  1 
ATOM   1337 C CG  . TYR   A 1 164 ? -22.50584  -33.23858 -118.53683 1.000 28.81164  ? 164 TYR   A CG  1 
ATOM   1338 C CD1 . TYR   A 1 164 ? -22.05279  -34.30975 -119.31304 1.000 29.54931  ? 164 TYR   A CD1 1 
ATOM   1339 C CD2 . TYR   A 1 164 ? -21.79027  -32.04042 -118.59140 1.000 21.04326  ? 164 TYR   A CD2 1 
ATOM   1340 C CE1 . TYR   A 1 164 ? -20.92442  -34.18829 -120.12706 1.000 21.11594  ? 164 TYR   A CE1 1 
ATOM   1341 C CE2 . TYR   A 1 164 ? -20.66265  -31.91558 -119.39385 1.000 24.87835  ? 164 TYR   A CE2 1 
ATOM   1342 C CZ  . TYR   A 1 164 ? -20.23779  -32.99261 -120.16466 1.000 25.43943  ? 164 TYR   A CZ  1 
ATOM   1343 O OH  . TYR   A 1 164 ? -19.12742  -32.87873 -120.97440 1.000 35.84591  ? 164 TYR   A OH  1 
ATOM   1344 N N   . ALA   A 1 165 ? -26.80947  -33.75666 -117.00768 1.000 19.21139  ? 165 ALA   A N   1 
ATOM   1345 C CA  . ALA   A 1 165 ? -27.82933  -33.91207 -115.97924 1.000 16.36767  ? 165 ALA   A CA  1 
ATOM   1346 C C   . ALA   A 1 165 ? -28.70616  -35.11991 -116.27122 1.000 17.25590  ? 165 ALA   A C   1 
ATOM   1347 O O   . ALA   A 1 165 ? -29.03662  -35.89285 -115.36260 1.000 16.45459  ? 165 ALA   A O   1 
ATOM   1348 C CB  . ALA   A 1 165 ? -28.65203  -32.63050 -115.87282 1.000 14.38476  ? 165 ALA   A CB  1 
ATOM   1349 N N   . TYR   A 1 166 ? -29.05487  -35.31375 -117.54694 1.000 18.15761  ? 166 TYR   A N   1 
ATOM   1350 C CA  . TYR   A 1 166 ? -29.89530  -36.43666 -117.94952 1.000 20.67702  ? 166 TYR   A CA  1 
ATOM   1351 C C   . TYR   A 1 166 ? -29.23305  -37.77293 -117.62592 1.000 21.22892  ? 166 TYR   A C   1 
ATOM   1352 O O   . TYR   A 1 166 ? -29.87282  -38.68615 -117.09018 1.000 18.35592  ? 166 TYR   A O   1 
ATOM   1353 C CB  . TYR   A 1 166 ? -30.18914  -36.33122 -119.44485 1.000 16.49259  ? 166 TYR   A CB  1 
ATOM   1354 C CG  . TYR   A 1 166 ? -30.98296  -37.47866 -120.01027 1.000 18.94119  ? 166 TYR   A CG  1 
ATOM   1355 C CD1 . TYR   A 1 166 ? -32.32725  -37.65328 -119.68297 1.000 19.64064  ? 166 TYR   A CD1 1 
ATOM   1356 C CD2 . TYR   A 1 166 ? -30.39381  -38.39154 -120.87765 1.000 18.79064  ? 166 TYR   A CD2 1 
ATOM   1357 C CE1 . TYR   A 1 166 ? -33.06637  -38.71182 -120.20817 1.000 17.01352  ? 166 TYR   A CE1 1 
ATOM   1358 C CE2 . TYR   A 1 166 ? -31.12435  -39.44699 -121.41219 1.000 18.95259  ? 166 TYR   A CE2 1 
ATOM   1359 C CZ  . TYR   A 1 166 ? -32.45768  -39.59803 -121.07691 1.000 19.18466  ? 166 TYR   A CZ  1 
ATOM   1360 O OH  . TYR   A 1 166 ? -33.17103  -40.64568 -121.61155 1.000 21.65312  ? 166 TYR   A OH  1 
ATOM   1361 N N   . GLU   A 1 167 ? -27.94978  -37.90676 -117.96456 1.000 15.20450  ? 167 GLU   A N   1 
ATOM   1362 C CA  . GLU   A 1 167 ? -27.21604  -39.11937 -117.63735 1.000 21.85886  ? 167 GLU   A CA  1 
ATOM   1363 C C   . GLU   A 1 167 ? -27.20225  -39.38030 -116.12897 1.000 23.74169  ? 167 GLU   A C   1 
ATOM   1364 O O   . GLU   A 1 167 ? -27.37374  -40.52401 -115.69056 1.000 19.65075  ? 167 GLU   A O   1 
ATOM   1365 C CB  . GLU   A 1 167 ? -25.79725  -39.02152 -118.18860 1.000 20.10652  ? 167 GLU   A CB  1 
ATOM   1366 C CG  . GLU   A 1 167 ? -24.91791  -40.19265 -117.80848 1.000 27.60919  ? 167 GLU   A CG  1 
ATOM   1367 C CD  . GLU   A 1 167 ? -23.56626  -40.16001 -118.50376 1.000 47.46506  ? 167 GLU   A CD  1 
ATOM   1368 O OE1 . GLU   A 1 167 ? -22.74725  -39.25361 -118.20368 1.000 42.44216  ? 167 GLU   A OE1 1 
ATOM   1369 O OE2 . GLU   A 1 167 ? -23.32819  -41.04655 -119.35312 1.000 42.98789  ? 167 GLU   A OE2 1 
ATOM   1370 N N   . ALA   A 1 168 ? -27.01310  -38.33454 -115.32001 1.000 14.46180  ? 168 ALA   A N   1 
ATOM   1371 C CA  . ALA   A 1 168 ? -26.95731  -38.52184 -113.86801 1.000 13.77174  ? 168 ALA   A CA  1 
ATOM   1372 C C   . ALA   A 1 168 ? -28.30034  -38.98237 -113.30723 1.000 21.71219  ? 168 ALA   A C   1 
ATOM   1373 O O   . ALA   A 1 168 ? -28.34193  -39.82104 -112.39841 1.000 21.97482  ? 168 ALA   A O   1 
ATOM   1374 C CB  . ALA   A 1 168 ? -26.51101  -37.22920 -113.18960 1.000 13.53682  ? 168 ALA   A CB  1 
ATOM   1375 N N   . ASP   A 1 169 ? -29.40780  -38.45891 -113.83557 1.000 19.35726  ? 169 ASP   A N   1 
ATOM   1376 C CA  . ASP   A 1 169 ? -30.73821  -38.91503 -113.43302 1.000 16.71882  ? 169 ASP   A CA  1 
ATOM   1377 C C   . ASP   A 1 169 ? -31.68874  -38.76020 -114.60207 1.000 22.35903  ? 169 ASP   A C   1 
ATOM   1378 O O   . ASP   A 1 169 ? -32.35152  -37.72411 -114.75273 1.000 18.28272  ? 169 ASP   A O   1 
ATOM   1379 C CB  . ASP   A 1 169 ? -31.26494  -38.15782 -112.21362 1.000 18.81444  ? 169 ASP   A CB  1 
ATOM   1380 C CG  . ASP   A 1 169 ? -32.64617  -38.64484 -111.76000 1.000 16.21335  ? 169 ASP   A CG  1 
ATOM   1381 O OD1 . ASP   A 1 169 ? -33.14727  -39.65525 -112.30029 1.000 15.76725  ? 169 ASP   A OD1 1 
ATOM   1382 O OD2 . ASP   A 1 169 ? -33.23785  -38.00436 -110.85599 1.000 16.41533  ? 169 ASP   A OD2 1 
ATOM   1383 N N   . PRO   A 1 170 ? -31.84115  -39.80703 -115.41956 1.000 21.98275  ? 170 PRO   A N   1 
ATOM   1384 C CA  . PRO   A 1 170 ? -32.71993  -39.69829 -116.59468 1.000 18.17351  ? 170 PRO   A CA  1 
ATOM   1385 C C   . PRO   A 1 170 ? -34.20579  -39.63767 -116.26001 1.000 21.68119  ? 170 PRO   A C   1 
ATOM   1386 O O   . PRO   A 1 170 ? -35.00259  -39.39150 -117.17137 1.000 24.46200  ? 170 PRO   A O   1 
ATOM   1387 C CB  . PRO   A 1 170 ? -32.36855  -40.94721 -117.41688 1.000 18.97414  ? 170 PRO   A CB  1 
ATOM   1388 C CG  . PRO   A 1 170 ? -31.80431  -41.92480 -116.41562 1.000 19.10887  ? 170 PRO   A CG  1 
ATOM   1389 C CD  . PRO   A 1 170 ? -31.18647  -41.12519 -115.30811 1.000 16.49199  ? 170 PRO   A CD  1 
ATOM   1390 N N   . ASP   A 1 171 ? -34.60930  -39.81389 -115.00089 1.000 20.03730  ? 171 ASP   A N   1 
ATOM   1391 C CA  . ASP   A 1 171 ? -36.01589  -39.67615 -114.63693 1.000 20.66157  ? 171 ASP   A CA  1 
ATOM   1392 C C   . ASP   A 1 171 ? -36.37798  -38.26763 -114.20948 1.000 19.56397  ? 171 ASP   A C   1 
ATOM   1393 O O   . ASP   A 1 171 ? -37.54999  -38.01250 -113.91870 1.000 15.59625  ? 171 ASP   A O   1 
ATOM   1394 C CB  . ASP   A 1 171 ? -36.38860  -40.62991 -113.49939 1.000 17.91607  ? 171 ASP   A CB  1 
ATOM   1395 C CG  . ASP   A 1 171 ? -36.42003  -42.06812 -113.94423 1.000 29.33683  ? 171 ASP   A CG  1 
ATOM   1396 O OD1 . ASP   A 1 171 ? -37.02246  -42.33346 -115.00260 1.000 33.66477  ? 171 ASP   A OD1 1 
ATOM   1397 O OD2 . ASP   A 1 171 ? -35.84608  -42.92847 -113.23951 1.000 30.30677  ? 171 ASP   A OD2 1 
ATOM   1398 N N   . ALA   A 1 172 ? -35.40574  -37.36868 -114.11984 1.000 13.11658  ? 172 ALA   A N   1 
ATOM   1399 C CA  . ALA   A 1 172 ? -35.67823  -36.00656 -113.70576 1.000 14.76294  ? 172 ALA   A CA  1 
ATOM   1400 C C   . ALA   A 1 172 ? -36.17790  -35.19072 -114.88885 1.000 16.96771  ? 172 ALA   A C   1 
ATOM   1401 O O   . ALA   A 1 172 ? -35.80709  -35.43797 -116.03581 1.000 18.79182  ? 172 ALA   A O   1 
ATOM   1402 C CB  . ALA   A 1 172 ? -34.41666  -35.36904 -113.12428 1.000 13.95936  ? 172 ALA   A CB  1 
ATOM   1403 N N   . LEU   A 1 173 ? -37.03633  -34.21454 -114.60779 1.000 19.11044  ? 173 LEU   A N   1 
ATOM   1404 C CA  . LEU   A 1 173 ? -37.42834  -33.25050 -115.62409 1.000 16.67333  ? 173 LEU   A CA  1 
ATOM   1405 C C   . LEU   A 1 173 ? -36.42016  -32.10856 -115.59738 1.000 18.03708  ? 173 LEU   A C   1 
ATOM   1406 O O   . LEU   A 1 173 ? -36.15790  -31.52798 -114.53820 1.000 20.58281  ? 173 LEU   A O   1 
ATOM   1407 C CB  . LEU   A 1 173 ? -38.85026  -32.74455 -115.38353 1.000 17.42617  ? 173 LEU   A CB  1 
ATOM   1408 C CG  . LEU   A 1 173 ? -39.95275  -33.81274 -115.28952 1.000 23.41773  ? 173 LEU   A CG  1 
ATOM   1409 C CD1 . LEU   A 1 173 ? -41.31295  -33.16953 -115.05606 1.000 20.72806  ? 173 LEU   A CD1 1 
ATOM   1410 C CD2 . LEU   A 1 173 ? -39.99900  -34.64015 -116.54732 1.000 21.59532  ? 173 LEU   A CD2 1 
ATOM   1411 N N   . LEU   A 1 174 ? -35.81932  -31.82167 -116.74489 1.000 14.88277  ? 174 LEU   A N   1 
ATOM   1412 C CA  . LEU   A 1 174 ? -34.75540  -30.83127 -116.84057 1.000 15.71655  ? 174 LEU   A CA  1 
ATOM   1413 C C   . LEU   A 1 174 ? -35.30393  -29.54420 -117.45204 1.000 16.14350  ? 174 LEU   A C   1 
ATOM   1414 O O   . LEU   A 1 174 ? -35.96505  -29.57581 -118.50145 1.000 14.72404  ? 174 LEU   A O   1 
ATOM   1415 C CB  . LEU   A 1 174 ? -33.58326  -31.38855 -117.66240 1.000 16.35920  ? 174 LEU   A CB  1 
ATOM   1416 C CG  . LEU   A 1 174 ? -33.08506  -32.76188 -117.17142 1.000 21.58661  ? 174 LEU   A CG  1 
ATOM   1417 C CD1 . LEU   A 1 174 ? -31.82004  -33.25942 -117.91708 1.000 14.65709  ? 174 LEU   A CD1 1 
ATOM   1418 C CD2 . LEU   A 1 174 ? -32.86207  -32.75590 -115.65148 1.000 11.04407  ? 174 LEU   A CD2 1 
ATOM   1419 N N   . PHE   A 1 175 ? -35.01931  -28.41574 -116.79999 1.000 14.82909  ? 175 PHE   A N   1 
ATOM   1420 C CA  . PHE   A 1 175 ? -35.62973  -27.13455 -117.13589 1.000 15.75234  ? 175 PHE   A CA  1 
ATOM   1421 C C   . PHE   A 1 175 ? -34.60416  -26.11087 -117.59313 1.000 14.32339  ? 175 PHE   A C   1 
ATOM   1422 O O   . PHE   A 1 175 ? -33.50725  -26.03767 -117.03853 1.000 16.28308  ? 175 PHE   A O   1 
ATOM   1423 C CB  . PHE   A 1 175 ? -36.36048  -26.54891 -115.94010 1.000 12.21288  ? 175 PHE   A CB  1 
ATOM   1424 C CG  . PHE   A 1 175 ? -37.71455  -27.11626 -115.72906 1.000 16.88177  ? 175 PHE   A CG  1 
ATOM   1425 C CD1 . PHE   A 1 175 ? -37.86914  -28.38089 -115.18404 1.000 13.89584  ? 175 PHE   A CD1 1 
ATOM   1426 C CD2 . PHE   A 1 175 ? -38.84127  -26.38602 -116.06568 1.000 13.56403  ? 175 PHE   A CD2 1 
ATOM   1427 C CE1 . PHE   A 1 175 ? -39.12728  -28.90817 -114.99237 1.000 19.48589  ? 175 PHE   A CE1 1 
ATOM   1428 C CE2 . PHE   A 1 175 ? -40.09606  -26.90773 -115.87196 1.000 14.87590  ? 175 PHE   A CE2 1 
ATOM   1429 C CZ  . PHE   A 1 175 ? -40.24005  -28.17465 -115.32900 1.000 14.05484  ? 175 PHE   A CZ  1 
ATOM   1430 N N   . TYR   A 1 176 ? -34.98127  -25.29914 -118.58764 1.000 18.27766  ? 176 TYR   A N   1 
ATOM   1431 C CA  . TYR   A 1 176 ? -34.36394  -23.99132 -118.78629 1.000 16.61639  ? 176 TYR   A CA  1 
ATOM   1432 C C   . TYR   A 1 176 ? -35.17022  -22.95604 -117.99671 1.000 12.37540  ? 176 TYR   A C   1 
ATOM   1433 O O   . TYR   A 1 176 ? -36.39034  -22.87847 -118.14235 1.000 10.63445  ? 176 TYR   A O   1 
ATOM   1434 C CB  . TYR   A 1 176 ? -34.28954  -23.60614 -120.27709 1.000 13.92137  ? 176 TYR   A CB  1 
ATOM   1435 C CG  . TYR   A 1 176 ? -33.73056  -22.19787 -120.44063 1.000 15.13597  ? 176 TYR   A CG  1 
ATOM   1436 C CD1 . TYR   A 1 176 ? -32.36118  -21.96810 -120.42249 1.000 14.75781  ? 176 TYR   A CD1 1 
ATOM   1437 C CD2 . TYR   A 1 176 ? -34.57550  -21.09337 -120.50237 1.000 12.80835  ? 176 TYR   A CD2 1 
ATOM   1438 C CE1 . TYR   A 1 176 ? -31.84183  -20.68539 -120.50703 1.000 13.85026  ? 176 TYR   A CE1 1 
ATOM   1439 C CE2 . TYR   A 1 176 ? -34.07300  -19.80481 -120.57808 1.000 14.34550  ? 176 TYR   A CE2 1 
ATOM   1440 C CZ  . TYR   A 1 176 ? -32.70472  -19.60499 -120.58374 1.000 19.88480  ? 176 TYR   A CZ  1 
ATOM   1441 O OH  . TYR   A 1 176 ? -32.20443  -18.32375 -120.66735 1.000 17.55044  ? 176 TYR   A OH  1 
ATOM   1442 N N   . ASN   A 1 177 ? -34.49009  -22.14161 -117.18431 1.000 19.41440  ? 177 ASN   A N   1 
ATOM   1443 C CA  . ASN   A 1 177 ? -35.14895  -21.25724 -116.21489 1.000 17.63337  ? 177 ASN   A CA  1 
ATOM   1444 C C   . ASN   A 1 177 ? -34.70637  -19.81294 -116.42458 1.000 17.09492  ? 177 ASN   A C   1 
ATOM   1445 O O   . ASN   A 1 177 ? -33.50362  -19.53704 -116.51831 1.000 19.09490  ? 177 ASN   A O   1 
ATOM   1446 C CB  . ASN   A 1 177 ? -34.83200  -21.69843 -114.77382 1.000 13.29709  ? 177 ASN   A CB  1 
ATOM   1447 C CG  . ASN   A 1 177 ? -35.76320  -21.06156 -113.73029 1.000 15.66447  ? 177 ASN   A CG  1 
ATOM   1448 O OD1 . ASN   A 1 177 ? -36.98451  -21.10497 -113.86028 1.000 14.11479  ? 177 ASN   A OD1 1 
ATOM   1449 N ND2 . ASN   A 1 177 ? -35.17610  -20.46468 -112.69343 1.000 12.55044  ? 177 ASN   A ND2 1 
ATOM   1450 N N   . ASP   A 1 178 ? -35.66641  -18.88646 -116.45552 1.000 15.31848  ? 178 ASP   A N   1 
ATOM   1451 C CA  . ASP   A 1 178 ? -35.30842  -17.50589 -116.76514 1.000 22.95861  ? 178 ASP   A CA  1 
ATOM   1452 C C   . ASP   A 1 178 ? -36.40109  -16.53761 -116.32112 1.000 17.06971  ? 178 ASP   A C   1 
ATOM   1453 O O   . ASP   A 1 178 ? -37.54661  -16.92407 -116.06961 1.000 18.83508  ? 178 ASP   A O   1 
ATOM   1454 C CB  . ASP   A 1 178 ? -35.02817  -17.33094 -118.26303 1.000 17.70556  ? 178 ASP   A CB  1 
ATOM   1455 C CG  . ASP   A 1 178 ? -33.96759  -16.29560 -118.52694 1.000 16.17392  ? 178 ASP   A CG  1 
ATOM   1456 O OD1 . ASP   A 1 178 ? -33.64229  -15.53265 -117.58909 1.000 19.22354  ? 178 ASP   A OD1 1 
ATOM   1457 O OD2 . ASP   A 1 178 ? -33.45065  -16.24601 -119.65951 1.000 20.32787  ? 178 ASP   A OD2 1 
ATOM   1458 N N   . TYR   A 1 179 ? -36.01979  -15.26521 -116.24261 1.000 16.59276  ? 179 TYR   A N   1 
ATOM   1459 C CA  . TYR   A 1 179 ? -36.88154  -14.15701 -115.83833 1.000 20.28811  ? 179 TYR   A CA  1 
ATOM   1460 C C   . TYR   A 1 179 ? -37.12212  -13.21288 -117.01383 1.000 18.86067  ? 179 TYR   A C   1 
ATOM   1461 O O   . TYR   A 1 179 ? -36.46972  -13.29691 -118.05987 1.000 15.56075  ? 179 TYR   A O   1 
ATOM   1462 C CB  . TYR   A 1 179 ? -36.26092  -13.38281 -114.67065 1.000 21.48652  ? 179 TYR   A CB  1 
ATOM   1463 C CG  . TYR   A 1 179 ? -34.98954  -12.63765 -115.04493 1.000 20.09063  ? 179 TYR   A CG  1 
ATOM   1464 C CD1 . TYR   A 1 179 ? -33.73911  -13.26194 -114.95642 1.000 24.03546  ? 179 TYR   A CD1 1 
ATOM   1465 C CD2 . TYR   A 1 179 ? -35.03232  -11.31488 -115.49331 1.000 21.30186  ? 179 TYR   A CD2 1 
ATOM   1466 C CE1 . TYR   A 1 179 ? -32.55846  -12.57798 -115.29746 1.000 23.90553  ? 179 TYR   A CE1 1 
ATOM   1467 C CE2 . TYR   A 1 179 ? -33.86340  -10.63012 -115.84405 1.000 22.56738  ? 179 TYR   A CE2 1 
ATOM   1468 C CZ  . TYR   A 1 179 ? -32.63013  -11.26836 -115.73585 1.000 24.75126  ? 179 TYR   A CZ  1 
ATOM   1469 O OH  . TYR   A 1 179 ? -31.47398  -10.60942 -116.07732 1.000 27.13251  ? 179 TYR   A OH  1 
ATOM   1470 N N   . ASN   A 1 180 ? -38.05530  -12.27780 -116.80765 1.000 20.55703  ? 180 ASN   A N   1 
ATOM   1471 C CA  . ASN   A 1 180 ? -38.56478  -11.41007 -117.87727 1.000 19.20584  ? 180 ASN   A CA  1 
ATOM   1472 C C   . ASN   A 1 180 ? -38.97700  -12.24912 -119.08193 1.000 20.30001  ? 180 ASN   A C   1 
ATOM   1473 O O   . ASN   A 1 180 ? -38.88548  -11.83273 -120.24019 1.000 20.52075  ? 180 ASN   A O   1 
ATOM   1474 C CB  . ASN   A 1 180 ? -37.56097  -10.32184 -118.24637 1.000 15.30493  ? 180 ASN   A CB  1 
ATOM   1475 C CG  . ASN   A 1 180 ? -37.46193  -9.25040  -117.16648 1.000 24.57786  ? 180 ASN   A CG  1 
ATOM   1476 O OD1 . ASN   A 1 180 ? -38.25927  -9.22641  -116.21986 1.000 23.39640  ? 180 ASN   A OD1 1 
ATOM   1477 N ND2 . ASN   A 1 180 ? -36.50537  -8.35458  -117.30929 1.000 22.48342  ? 180 ASN   A ND2 1 
ATOM   1478 N N   . GLU   A 1 181 ? -39.47370  -13.44010 -118.77105 1.000 15.97368  ? 181 GLU   A N   1 
ATOM   1479 C CA  . GLU   A 1 181 ? -39.83730  -14.46477 -119.72534 1.000 21.00032  ? 181 GLU   A CA  1 
ATOM   1480 C C   . GLU   A 1 181 ? -41.06405  -14.09528 -120.54984 1.000 19.17210  ? 181 GLU   A C   1 
ATOM   1481 O O   . GLU   A 1 181 ? -41.33770  -14.76732 -121.54539 1.000 20.25167  ? 181 GLU   A O   1 
ATOM   1482 C CB  . GLU   A 1 181 ? -40.06108  -15.77138 -118.95384 1.000 16.66204  ? 181 GLU   A CB  1 
ATOM   1483 C CG  . GLU   A 1 181 ? -41.31601  -15.78601 -118.05263 1.000 16.34264  ? 181 GLU   A CG  1 
ATOM   1484 C CD  . GLU   A 1 181 ? -41.28898  -14.75106 -116.90294 1.000 18.26822  ? 181 GLU   A CD  1 
ATOM   1485 O OE1 . GLU   A 1 181 ? -40.30817  -14.69025 -116.13467 1.000 13.46256  ? 181 GLU   A OE1 1 
ATOM   1486 O OE2 . GLU   A 1 181 ? -42.27051  -13.99497 -116.76306 1.000 19.88255  ? 181 GLU   A OE2 1 
ATOM   1487 N N   . CYS   A 1 182 ? -41.80253  -13.05194 -120.17427 1.000 15.95559  ? 182 CYS   A N   1 
ATOM   1488 C CA  . CYS   A 1 182 ? -42.98124  -12.64309 -120.92090 1.000 14.93146  ? 182 CYS   A CA  1 
ATOM   1489 C C   . CYS   A 1 182 ? -42.78548  -11.36396 -121.72916 1.000 17.39577  ? 182 CYS   A C   1 
ATOM   1490 O O   . CYS   A 1 182 ? -43.70888  -10.95280 -122.43730 1.000 19.26090  ? 182 CYS   A O   1 
ATOM   1491 C CB  . CYS   A 1 182 ? -44.17239  -12.47565 -119.96597 1.000 18.37258  ? 182 CYS   A CB  1 
ATOM   1492 S SG  . CYS   A 1 182 ? -44.59177  -13.99171 -119.09156 1.000 17.72824  ? 182 CYS   A SG  1 
ATOM   1493 N N   . PHE   A 1 183 ? -41.63960  -10.70856 -121.63391 1.000 20.21313  ? 183 PHE   A N   1 
ATOM   1494 C CA  . PHE   A 1 183 ? -41.39353  -9.56878  -122.51604 1.000 23.34032  ? 183 PHE   A CA  1 
ATOM   1495 C C   . PHE   A 1 183 ? -41.10874  -10.08840 -123.92231 1.000 23.26982  ? 183 PHE   A C   1 
ATOM   1496 O O   . PHE   A 1 183 ? -40.18154  -10.89412 -124.09935 1.000 22.28197  ? 183 PHE   A O   1 
ATOM   1497 C CB  . PHE   A 1 183 ? -40.24562  -8.71482  -121.99389 1.000 16.21546  ? 183 PHE   A CB  1 
ATOM   1498 C CG  . PHE   A 1 183 ? -40.52446  -8.09900  -120.64844 1.000 19.90963  ? 183 PHE   A CG  1 
ATOM   1499 C CD1 . PHE   A 1 183 ? -41.82473  -8.03095  -120.15811 1.000 23.85047  ? 183 PHE   A CD1 1 
ATOM   1500 C CD2 . PHE   A 1 183 ? -39.49651  -7.59599  -119.87017 1.000 19.15596  ? 183 PHE   A CD2 1 
ATOM   1501 C CE1 . PHE   A 1 183 ? -42.08270  -7.47521  -118.91858 1.000 23.99564  ? 183 PHE   A CE1 1 
ATOM   1502 C CE2 . PHE   A 1 183 ? -39.74873  -7.04021  -118.62845 1.000 19.35390  ? 183 PHE   A CE2 1 
ATOM   1503 C CZ  . PHE   A 1 183 ? -41.03802  -6.97828  -118.15109 1.000 17.84317  ? 183 PHE   A CZ  1 
ATOM   1504 N N   . PRO   A 1 184 ? -41.88583  -9.67366  -124.93549 1.000 23.45619  ? 184 PRO   A N   1 
ATOM   1505 C CA  . PRO   A 1 184 ? -41.85701  -10.35733 -126.24375 1.000 18.17289  ? 184 PRO   A CA  1 
ATOM   1506 C C   . PRO   A 1 184 ? -40.48117  -10.62786 -126.81391 1.000 17.42764  ? 184 PRO   A C   1 
ATOM   1507 O O   . PRO   A 1 184 ? -40.23652  -11.72314 -127.32966 1.000 27.26328  ? 184 PRO   A O   1 
ATOM   1508 C CB  . PRO   A 1 184 ? -42.64694  -9.39008  -127.13214 1.000 19.02305  ? 184 PRO   A CB  1 
ATOM   1509 C CG  . PRO   A 1 184 ? -43.69945  -8.83067  -126.17791 1.000 23.53205  ? 184 PRO   A CG  1 
ATOM   1510 C CD  . PRO   A 1 184 ? -42.97474  -8.67343  -124.85646 1.000 22.81813  ? 184 PRO   A CD  1 
ATOM   1511 N N   . GLU   A 1 185 ? -39.56899  -9.67219  -126.74810 1.000 19.59845  ? 185 GLU   A N   1 
ATOM   1512 C CA  . GLU   A 1 185 ? -38.29046  -9.90477  -127.39337 1.000 27.85519  ? 185 GLU   A CA  1 
ATOM   1513 C C   . GLU   A 1 185 ? -37.49183  -10.95961 -126.65081 1.000 26.43141  ? 185 GLU   A C   1 
ATOM   1514 O O   . GLU   A 1 185 ? -36.87390  -11.82879 -127.27816 1.000 28.34876  ? 185 GLU   A O   1 
ATOM   1515 C CB  . GLU   A 1 185 ? -37.52843  -8.58789  -127.53930 1.000 25.97641  ? 185 GLU   A CB  1 
ATOM   1516 C CG  . GLU   A 1 185 ? -38.22441  -7.72227  -128.58903 1.000 56.81092  ? 185 GLU   A CG  1 
ATOM   1517 C CD  . GLU   A 1 185 ? -37.45163  -6.49348  -129.01183 1.000 68.93152  ? 185 GLU   A CD  1 
ATOM   1518 O OE1 . GLU   A 1 185 ? -36.52862  -6.62345  -129.84453 1.000 76.90051  ? 185 GLU   A OE1 1 
ATOM   1519 O OE2 . GLU   A 1 185 ? -37.79676  -5.39231  -128.53645 1.000 68.16219  ? 185 GLU   A OE2 1 
ATOM   1520 N N   . LYS   A 1 186 ? -37.51476  -10.92587 -125.31733 1.000 27.54514  ? 186 LYS   A N   1 
ATOM   1521 C CA  . LYS   A 1 186 ? -36.84097  -11.98184 -124.58078 1.000 26.51171  ? 186 LYS   A CA  1 
ATOM   1522 C C   . LYS   A 1 186 ? -37.58446  -13.29633 -124.74804 1.000 20.14086  ? 186 LYS   A C   1 
ATOM   1523 O O   . LYS   A 1 186 ? -36.95703  -14.35442 -124.85450 1.000 18.96055  ? 186 LYS   A O   1 
ATOM   1524 C CB  . LYS   A 1 186 ? -36.69276  -11.62157 -123.09927 1.000 17.71173  ? 186 LYS   A CB  1 
ATOM   1525 C CG  . LYS   A 1 186 ? -35.70852  -12.55799 -122.36606 1.000 22.22361  ? 186 LYS   A CG  1 
ATOM   1526 C CD  . LYS   A 1 186 ? -35.36794  -12.10489 -120.93618 1.000 19.85742  ? 186 LYS   A CD  1 
ATOM   1527 C CE  . LYS   A 1 186 ? -34.20315  -12.91872 -120.34641 1.000 19.65307  ? 186 LYS   A CE  1 
ATOM   1528 N NZ  . LYS   A 1 186 ? -33.79180  -12.41691 -118.99636 1.000 26.51539  ? 186 LYS   A NZ  1 
ATOM   1529 N N   . ARG   A 1 187 ? -38.92113  -13.24384 -124.79639 1.000 15.48241  ? 187 ARG   A N   1 
ATOM   1530 C CA  . ARG   A 1 187 ? -39.69647  -14.46223 -124.98968 1.000 16.17127  ? 187 ARG   A CA  1 
ATOM   1531 C C   . ARG   A 1 187 ? -39.27798  -15.18396 -126.26471 1.000 23.05265  ? 187 ARG   A C   1 
ATOM   1532 O O   . ARG   A 1 187 ? -39.11604  -16.40832 -126.26815 1.000 20.88524  ? 187 ARG   A O   1 
ATOM   1533 C CB  . ARG   A 1 187 ? -41.18277  -14.13493 -125.02422 1.000 18.70142  ? 187 ARG   A CB  1 
ATOM   1534 C CG  . ARG   A 1 187 ? -42.06657  -15.28458 -125.47475 1.000 22.15524  ? 187 ARG   A CG  1 
ATOM   1535 C CD  . ARG   A 1 187 ? -43.45984  -14.78009 -125.93798 1.000 23.64879  ? 187 ARG   A CD  1 
ATOM   1536 N NE  . ARG   A 1 187 ? -43.44356  -14.30703 -127.32510 1.000 26.09915  ? 187 ARG   A NE  1 
ATOM   1537 C CZ  . ARG   A 1 187 ? -44.10857  -13.24220 -127.78303 1.000 24.97779  ? 187 ARG   A CZ  1 
ATOM   1538 N NH1 . ARG   A 1 187 ? -44.85210  -12.49882 -126.98095 1.000 18.75981  ? 187 ARG   A NH1 1 
ATOM   1539 N NH2 . ARG   A 1 187 ? -44.02050  -12.90759 -129.05961 1.000 29.49558  ? 187 ARG   A NH2 1 
ATOM   1540 N N   . GLU   A 1 188 ? -39.07125  -14.43865 -127.35307 1.000 20.21969  ? 188 GLU   A N   1 
ATOM   1541 C CA  . GLU   A 1 188 ? -38.70104  -15.07194 -128.61179 1.000 22.40544  ? 188 GLU   A CA  1 
ATOM   1542 C C   . GLU   A 1 188 ? -37.28633  -15.63563 -128.56936 1.000 19.64155  ? 188 GLU   A C   1 
ATOM   1543 O O   . GLU   A 1 188 ? -36.99593  -16.61223 -129.26845 1.000 20.35986  ? 188 GLU   A O   1 
ATOM   1544 C CB  . GLU   A 1 188 ? -38.85125  -14.07666 -129.76415 1.000 17.53211  ? 188 GLU   A CB  1 
ATOM   1545 C CG  . GLU   A 1 188 ? -40.29541  -13.72466 -130.06074 1.000 16.17691  ? 188 GLU   A CG  1 
ATOM   1546 C CD  . GLU   A 1 188 ? -41.14176  -14.93483 -130.46124 1.000 27.15459  ? 188 GLU   A CD  1 
ATOM   1547 O OE1 . GLU   A 1 188 ? -40.71762  -15.66507 -131.38124 1.000 24.65770  ? 188 GLU   A OE1 1 
ATOM   1548 O OE2 . GLU   A 1 188 ? -42.23182  -15.14949 -129.86543 1.000 20.83144  ? 188 GLU   A OE2 1 
ATOM   1549 N N   . LYS   A 1 189 ? -36.39193  -15.02994 -127.78271 1.000 20.78957  ? 189 LYS   A N   1 
ATOM   1550 C CA  . LYS   A 1 189 ? -35.05851  -15.60041 -127.61005 1.000 24.41561  ? 189 LYS   A CA  1 
ATOM   1551 C C   . LYS   A 1 189 ? -35.13333  -16.90643 -126.83030 1.000 21.44420  ? 189 LYS   A C   1 
ATOM   1552 O O   . LYS   A 1 189 ? -34.52287  -17.91148 -127.21927 1.000 20.87944  ? 189 LYS   A O   1 
ATOM   1553 C CB  . LYS   A 1 189 ? -34.13510  -14.60519 -126.90266 1.000 22.58486  ? 189 LYS   A CB  1 
ATOM   1554 C CG  . LYS   A 1 189 ? -33.89222  -13.31939 -127.66430 1.000 20.88358  ? 189 LYS   A CG  1 
ATOM   1555 C CD  . LYS   A 1 189 ? -32.78454  -12.50130 -127.02577 1.000 28.63145  ? 189 LYS   A CD  1 
ATOM   1556 C CE  . LYS   A 1 189 ? -32.63439  -11.12124 -127.67669 1.000 27.87505  ? 189 LYS   A CE  1 
ATOM   1557 N NZ  . LYS   A 1 189 ? -31.66120  -10.29523 -126.90920 1.000 37.49105  ? 189 LYS   A NZ  1 
ATOM   1558 N N   . ILE   A 1 190 ? -35.88358  -16.91088 -125.72424 1.000 19.52850  ? 190 ILE   A N   1 
ATOM   1559 C CA  . ILE   A 1 190 ? -36.02500  -18.13350 -124.94219 1.000 21.22083  ? 190 ILE   A CA  1 
ATOM   1560 C C   . ILE   A 1 190 ? -36.63598  -19.22563 -125.80317 1.000 18.03872  ? 190 ILE   A C   1 
ATOM   1561 O O   . ILE   A 1 190 ? -36.10288  -20.33789 -125.89875 1.000 16.29704  ? 190 ILE   A O   1 
ATOM   1562 C CB  . ILE   A 1 190 ? -36.84598  -17.87620 -123.66644 1.000 14.59067  ? 190 ILE   A CB  1 
ATOM   1563 C CG1 . ILE   A 1 190 ? -36.02551  -17.02617 -122.70079 1.000 14.84383  ? 190 ILE   A CG1 1 
ATOM   1564 C CG2 . ILE   A 1 190 ? -37.23727  -19.20796 -122.99392 1.000 8.84982   ? 190 ILE   A CG2 1 
ATOM   1565 C CD1 . ILE   A 1 190 ? -36.85933  -16.31245 -121.66876 1.000 16.07625  ? 190 ILE   A CD1 1 
ATOM   1566 N N   . PHE   A 1 191 ? -37.74033  -18.90140 -126.47765 1.000 19.05205  ? 191 PHE   A N   1 
ATOM   1567 C CA  . PHE   A 1 191 ? -38.35740  -19.82668 -127.41758 1.000 17.45300  ? 191 PHE   A CA  1 
ATOM   1568 C C   . PHE   A 1 191 ? -37.33161  -20.35898 -128.40908 1.000 26.29273  ? 191 PHE   A C   1 
ATOM   1569 O O   . PHE   A 1 191 ? -37.14900  -21.57519 -128.54082 1.000 24.28763  ? 191 PHE   A O   1 
ATOM   1570 C CB  . PHE   A 1 191 ? -39.50227  -19.12298 -128.14459 1.000 20.86701  ? 191 PHE   A CB  1 
ATOM   1571 C CG  . PHE   A 1 191 ? -40.19611  -19.97896 -129.16740 1.000 23.78664  ? 191 PHE   A CG  1 
ATOM   1572 C CD1 . PHE   A 1 191 ? -41.24643  -20.80055 -128.79846 1.000 16.10665  ? 191 PHE   A CD1 1 
ATOM   1573 C CD2 . PHE   A 1 191 ? -39.81296  -19.94047 -130.50701 1.000 26.52328  ? 191 PHE   A CD2 1 
ATOM   1574 C CE1 . PHE   A 1 191 ? -41.89226  -21.58493 -129.73189 1.000 21.39998  ? 191 PHE   A CE1 1 
ATOM   1575 C CE2 . PHE   A 1 191 ? -40.46179  -20.72452 -131.45658 1.000 22.99750  ? 191 PHE   A CE2 1 
ATOM   1576 C CZ  . PHE   A 1 191 ? -41.50103  -21.55252 -131.06364 1.000 18.03324  ? 191 PHE   A CZ  1 
ATOM   1577 N N   . ALA   A 1 192 ? -36.62845  -19.45321 -129.09565 1.000 22.38753  ? 192 ALA   A N   1 
ATOM   1578 C CA  . ALA   A 1 192 ? -35.69445  -19.87973 -130.13244 1.000 23.41632  ? 192 ALA   A CA  1 
ATOM   1579 C C   . ALA   A 1 192 ? -34.59927  -20.75572 -129.55287 1.000 21.60272  ? 192 ALA   A C   1 
ATOM   1580 O O   . ALA   A 1 192 ? -34.19941  -21.75188 -130.16717 1.000 19.91723  ? 192 ALA   A O   1 
ATOM   1581 C CB  . ALA   A 1 192 ? -35.08860  -18.66725 -130.83941 1.000 21.05723  ? 192 ALA   A CB  1 
ATOM   1582 N N   . LEU   A 1 193 ? -34.10801  -20.40904 -128.36426 1.000 22.89414  ? 193 LEU   A N   1 
ATOM   1583 C CA  . LEU   A 1 193 ? -33.06976  -21.22229 -127.75011 1.000 23.28120  ? 193 LEU   A CA  1 
ATOM   1584 C C   . LEU   A 1 193 ? -33.58639  -22.62329 -127.42666 1.000 23.14843  ? 193 LEU   A C   1 
ATOM   1585 O O   . LEU   A 1 193 ? -32.94732  -23.62264 -127.76720 1.000 26.54030  ? 193 LEU   A O   1 
ATOM   1586 C CB  . LEU   A 1 193 ? -32.53782  -20.53653 -126.49786 1.000 22.96219  ? 193 LEU   A CB  1 
ATOM   1587 C CG  . LEU   A 1 193 ? -31.68098  -21.47698 -125.65181 1.000 23.49524  ? 193 LEU   A CG  1 
ATOM   1588 C CD1 . LEU   A 1 193 ? -30.46317  -21.91977 -126.46755 1.000 21.59072  ? 193 LEU   A CD1 1 
ATOM   1589 C CD2 . LEU   A 1 193 ? -31.26975  -20.82313 -124.33836 1.000 15.74677  ? 193 LEU   A CD2 1 
ATOM   1590 N N   . VAL   A 1 194 ? -34.74621  -22.71840 -126.77680 1.000 18.30525  ? 194 VAL   A N   1 
ATOM   1591 C CA  . VAL   A 1 194 ? -35.23845  -24.02396 -126.34585 1.000 23.01656  ? 194 VAL   A CA  1 
ATOM   1592 C C   . VAL   A 1 194 ? -35.61251  -24.87830 -127.55168 1.000 21.78151  ? 194 VAL   A C   1 
ATOM   1593 O O   . VAL   A 1 194 ? -35.26903  -26.06420 -127.61769 1.000 20.47231  ? 194 VAL   A O   1 
ATOM   1594 C CB  . VAL   A 1 194 ? -36.41981  -23.86261 -125.37111 1.000 23.23177  ? 194 VAL   A CB  1 
ATOM   1595 C CG1 . VAL   A 1 194 ? -37.07799  -25.23119 -125.06600 1.000 14.68715  ? 194 VAL   A CG1 1 
ATOM   1596 C CG2 . VAL   A 1 194 ? -35.94219  -23.21416 -124.09836 1.000 15.73171  ? 194 VAL   A CG2 1 
ATOM   1597 N N   . LYS   A 1 195 ? -36.31651  -24.28577 -128.52098 1.000 22.12368  ? 195 LYS   A N   1 
ATOM   1598 C CA  . LYS   A 1 195 ? -36.63517  -24.98009 -129.76576 1.000 26.58941  ? 195 LYS   A CA  1 
ATOM   1599 C C   . LYS   A 1 195 ? -35.38324  -25.56155 -130.41477 1.000 25.07932  ? 195 LYS   A C   1 
ATOM   1600 O O   . LYS   A 1 195 ? -35.36924  -26.72242 -130.83443 1.000 22.26901  ? 195 LYS   A O   1 
ATOM   1601 C CB  . LYS   A 1 195 ? -37.33423  -24.02703 -130.73732 1.000 24.74562  ? 195 LYS   A CB  1 
ATOM   1602 C CG  . LYS   A 1 195 ? -37.68281  -24.68181 -132.05698 1.000 31.31113  ? 195 LYS   A CG  1 
ATOM   1603 C CD  . LYS   A 1 195 ? -38.22270  -23.67396 -133.06918 1.000 37.72837  ? 195 LYS   A CD  1 
ATOM   1604 C CE  . LYS   A 1 195 ? -38.08196  -24.19301 -134.49585 1.000 34.43872  ? 195 LYS   A CE  1 
ATOM   1605 N NZ  . LYS   A 1 195 ? -38.81561  -25.48003 -134.67482 1.000 45.91647  ? 195 LYS   A NZ  1 
ATOM   1606 N N   . SER   A 1 196 ? -34.31084  -24.77566 -130.49036 1.000 19.69588  ? 196 SER   A N   1 
ATOM   1607 C CA  . SER   A 1 196 ? -33.09560  -25.28703 -131.10677 1.000 21.07597  ? 196 SER   A CA  1 
ATOM   1608 C C   . SER   A 1 196 ? -32.55645  -26.49345 -130.34312 1.000 26.07801  ? 196 SER   A C   1 
ATOM   1609 O O   . SER   A 1 196 ? -32.13129  -27.48158 -130.95332 1.000 31.30861  ? 196 SER   A O   1 
ATOM   1610 C CB  . SER   A 1 196 ? -32.04728  -24.17460 -131.21231 1.000 18.40396  ? 196 SER   A CB  1 
ATOM   1611 O OG  . SER   A 1 196 ? -31.17658  -24.17903 -130.09738 1.000 44.22011  ? 196 SER   A OG  1 
ATOM   1612 N N   . LEU   A 1 197 ? -32.60068  -26.44519 -129.00721 1.000 24.54222  ? 197 LEU   A N   1 
ATOM   1613 C CA  . LEU   A 1 197 ? -32.10632  -27.56337 -128.21050 1.000 29.65311  ? 197 LEU   A CA  1 
ATOM   1614 C C   . LEU   A 1 197 ? -32.95630  -28.80745 -128.42020 1.000 23.92690  ? 197 LEU   A C   1 
ATOM   1615 O O   . LEU   A 1 197 ? -32.42821  -29.90700 -128.64162 1.000 23.18969  ? 197 LEU   A O   1 
ATOM   1616 C CB  . LEU   A 1 197 ? -32.07959  -27.18329 -126.73855 1.000 24.56609  ? 197 LEU   A CB  1 
ATOM   1617 C CG  . LEU   A 1 197 ? -31.10996  -26.05014 -126.46551 1.000 27.14641  ? 197 LEU   A CG  1 
ATOM   1618 C CD1 . LEU   A 1 197 ? -31.33741  -25.53346 -125.06370 1.000 18.95616  ? 197 LEU   A CD1 1 
ATOM   1619 C CD2 . LEU   A 1 197 ? -29.68323  -26.54837 -126.65942 1.000 22.09459  ? 197 LEU   A CD2 1 
ATOM   1620 N N   . ARG   A 1 198 ? -34.27809  -28.65025 -128.34488 1.000 19.44900  ? 198 ARG   A N   1 
ATOM   1621 C CA  . ARG   A 1 198 ? -35.17272  -29.76983 -128.60536 1.000 21.27182  ? 198 ARG   A CA  1 
ATOM   1622 C C   . ARG   A 1 198 ? -34.96594  -30.31798 -130.00846 1.000 32.04462  ? 198 ARG   A C   1 
ATOM   1623 O O   . ARG   A 1 198 ? -35.06576  -31.53007 -130.22919 1.000 31.04495  ? 198 ARG   A O   1 
ATOM   1624 C CB  . ARG   A 1 198 ? -36.62333  -29.33433 -128.44159 1.000 20.78362  ? 198 ARG   A CB  1 
ATOM   1625 C CG  . ARG   A 1 198 ? -36.95499  -28.69873 -127.11372 1.000 33.33890  ? 198 ARG   A CG  1 
ATOM   1626 C CD  . ARG   A 1 198 ? -37.57099  -29.70184 -126.17397 1.000 27.89347  ? 198 ARG   A CD  1 
ATOM   1627 N NE  . ARG   A 1 198 ? -38.95695  -30.00126 -126.50457 1.000 29.56663  ? 198 ARG   A NE  1 
ATOM   1628 C CZ  . ARG   A 1 198 ? -39.59306  -31.08471 -126.06662 1.000 49.95859  ? 198 ARG   A CZ  1 
ATOM   1629 N NH1 . ARG   A 1 198 ? -38.94573  -31.95856 -125.29602 1.000 51.50733  ? 198 ARG   A NH1 1 
ATOM   1630 N NH2 . ARG   A 1 198 ? -40.86807  -31.30036 -126.39801 1.000 34.69729  ? 198 ARG   A NH2 1 
ATOM   1631 N N   . ASP   A 1 199 ? -34.68360  -29.43618 -130.97405 1.000 24.45280  ? 199 ASP   A N   1 
ATOM   1632 C CA  . ASP   A 1 199 ? -34.55367  -29.87184 -132.35905 1.000 25.62015  ? 199 ASP   A CA  1 
ATOM   1633 C C   . ASP   A 1 199 ? -33.31919  -30.72800 -132.56932 1.000 23.84689  ? 199 ASP   A C   1 
ATOM   1634 O O   . ASP   A 1 199 ? -33.25168  -31.45466 -133.56087 1.000 29.23797  ? 199 ASP   A O   1 
ATOM   1635 C CB  . ASP   A 1 199 ? -34.49857  -28.67026 -133.30679 1.000 25.39564  ? 199 ASP   A CB  1 
ATOM   1636 C CG  . ASP   A 1 199 ? -35.87136  -28.10097 -133.63355 1.000 22.51567  ? 199 ASP   A CG  1 
ATOM   1637 O OD1 . ASP   A 1 199 ? -36.89433  -28.69685 -133.25551 1.000 22.24332  ? 199 ASP   A OD1 1 
ATOM   1638 O OD2 . ASP   A 1 199 ? -35.92019  -27.03767 -134.28702 1.000 35.29845  ? 199 ASP   A OD2 1 
ATOM   1639 N N   . LYS   A 1 200 ? -32.33790  -30.64455 -131.67454 1.000 29.47614  ? 200 LYS   A N   1 
ATOM   1640 C CA  . LYS   A 1 200 ? -31.15824  -31.50003 -131.70801 1.000 25.88512  ? 200 LYS   A CA  1 
ATOM   1641 C C   . LYS   A 1 200 ? -31.27114  -32.70522 -130.77204 1.000 19.99507  ? 200 LYS   A C   1 
ATOM   1642 O O   . LYS   A 1 200 ? -30.27067  -33.38268 -130.53349 1.000 29.38658  ? 200 LYS   A O   1 
ATOM   1643 C CB  . LYS   A 1 200 ? -29.91922  -30.68018 -131.35384 1.000 23.27868  ? 200 LYS   A CB  1 
ATOM   1644 C CG  . LYS   A 1 200 ? -29.83253  -29.39205 -132.12488 1.000 28.79526  ? 200 LYS   A CG  1 
ATOM   1645 C CD  . LYS   A 1 200 ? -28.97157  -28.36301 -131.42228 1.000 35.57392  ? 200 LYS   A CD  1 
ATOM   1646 C CE  . LYS   A 1 200 ? -27.50142  -28.70148 -131.57557 1.000 47.50317  ? 200 LYS   A CE  1 
ATOM   1647 N NZ  . LYS   A 1 200 ? -26.71902  -27.52931 -132.04262 1.000 46.40842  ? 200 LYS   A NZ  1 
ATOM   1648 N N   . GLY   A 1 201 ? -32.45474  -32.98227 -130.23003 1.000 20.75522  ? 201 GLY   A N   1 
ATOM   1649 C CA  . GLY   A 1 201 ? -32.61013  -34.11555 -129.33308 1.000 26.56843  ? 201 GLY   A CA  1 
ATOM   1650 C C   . GLY   A 1 201 ? -32.05574  -33.93629 -127.93337 1.000 30.49742  ? 201 GLY   A C   1 
ATOM   1651 O O   . GLY   A 1 201 ? -31.88818  -34.92959 -127.21540 1.000 29.40713  ? 201 GLY   A O   1 
ATOM   1652 N N   . ILE   A 1 202 ? -31.75748  -32.70517 -127.52820 1.000 21.19666  ? 202 ILE   A N   1 
ATOM   1653 C CA  . ILE   A 1 202 ? -31.24827  -32.43539 -126.17639 1.000 22.86810  ? 202 ILE   A CA  1 
ATOM   1654 C C   . ILE   A 1 202 ? -32.35290  -32.69469 -125.15156 1.000 25.95044  ? 202 ILE   A C   1 
ATOM   1655 O O   . ILE   A 1 202 ? -33.48935  -32.21678 -125.32683 1.000 19.55647  ? 202 ILE   A O   1 
ATOM   1656 C CB  . ILE   A 1 202 ? -30.74266  -30.99187 -126.07829 1.000 25.22689  ? 202 ILE   A CB  1 
ATOM   1657 C CG1 . ILE   A 1 202 ? -29.60542  -30.75359 -127.07140 1.000 24.40750  ? 202 ILE   A CG1 1 
ATOM   1658 C CG2 . ILE   A 1 202 ? -30.29372  -30.67220 -124.65491 1.000 19.20040  ? 202 ILE   A CG2 1 
ATOM   1659 C CD1 . ILE   A 1 202 ? -28.38564  -31.57412 -126.79247 1.000 24.78499  ? 202 ILE   A CD1 1 
ATOM   1660 N N   . PRO   A 1 203 ? -32.07647  -33.41614 -124.07209 1.000 19.76453  ? 203 PRO   A N   1 
ATOM   1661 C CA  . PRO   A 1 203 ? -33.12018  -33.67655 -123.07170 1.000 22.41834  ? 203 PRO   A CA  1 
ATOM   1662 C C   . PRO   A 1 203 ? -33.48219  -32.44518 -122.24874 1.000 23.95058  ? 203 PRO   A C   1 
ATOM   1663 O O   . PRO   A 1 203 ? -33.10680  -32.33703 -121.07862 1.000 22.83532  ? 203 PRO   A O   1 
ATOM   1664 C CB  . PRO   A 1 203 ? -32.48949  -34.76349 -122.19367 1.000 15.00084  ? 203 PRO   A CB  1 
ATOM   1665 C CG  . PRO   A 1 203 ? -31.01685  -34.46625 -122.28182 1.000 20.52528  ? 203 PRO   A CG  1 
ATOM   1666 C CD  . PRO   A 1 203 ? -30.78246  -34.00956 -123.69787 1.000 16.58025  ? 203 PRO   A CD  1 
ATOM   1667 N N   . ILE   A 1 204 ? -34.21458  -31.50875 -122.83049 1.000 20.24153  ? 204 ILE   A N   1 
ATOM   1668 C CA  . ILE   A 1 204 ? -34.80422  -30.41715 -122.07214 1.000 21.72698  ? 204 ILE   A CA  1 
ATOM   1669 C C   . ILE   A 1 204 ? -36.31140  -30.64156 -122.08232 1.000 22.18082  ? 204 ILE   A C   1 
ATOM   1670 O O   . ILE   A 1 204 ? -36.93117  -30.69063 -123.14791 1.000 29.64526  ? 204 ILE   A O   1 
ATOM   1671 C CB  . ILE   A 1 204 ? -34.40253  -29.04562 -122.64083 1.000 18.56226  ? 204 ILE   A CB  1 
ATOM   1672 C CG1 . ILE   A 1 204 ? -35.19643  -27.92101 -121.98045 1.000 16.98279  ? 204 ILE   A CG1 1 
ATOM   1673 C CG2 . ILE   A 1 204 ? -34.59104  -29.01838 -124.14616 1.000 32.05196  ? 204 ILE   A CG2 1 
ATOM   1674 C CD1 . ILE   A 1 204 ? -34.65159  -26.55901 -122.26755 1.000 23.41355  ? 204 ILE   A CD1 1 
ATOM   1675 N N   . HIS   A 1 205 ? -36.89463  -30.83517 -120.90169 1.000 18.09587  ? 205 HIS   A N   1 
ATOM   1676 C CA  . HIS   A 1 205 ? -38.30310  -31.19026 -120.79278 1.000 16.90972  ? 205 HIS   A CA  1 
ATOM   1677 C C   . HIS   A 1 205 ? -39.19325  -30.02703 -120.37862 1.000 18.48635  ? 205 HIS   A C   1 
ATOM   1678 O O   . HIS   A 1 205 ? -40.41544  -30.14740 -120.45850 1.000 18.94943  ? 205 HIS   A O   1 
ATOM   1679 C CB  . HIS   A 1 205 ? -38.50090  -32.33519 -119.77764 1.000 17.01155  ? 205 HIS   A CB  1 
ATOM   1680 C CG  . HIS   A 1 205 ? -37.45130  -33.40143 -119.83954 1.000 22.66420  ? 205 HIS   A CG  1 
ATOM   1681 N ND1 . HIS   A 1 205 ? -36.23899  -33.29324 -119.18880 1.000 24.71625  ? 205 HIS   A ND1 1 
ATOM   1682 C CD2 . HIS   A 1 205 ? -37.43411  -34.60238 -120.46919 1.000 25.65245  ? 205 HIS   A CD2 1 
ATOM   1683 C CE1 . HIS   A 1 205 ? -35.51922  -34.37986 -119.41919 1.000 25.65172  ? 205 HIS   A CE1 1 
ATOM   1684 N NE2 . HIS   A 1 205 ? -36.22193  -35.19156 -120.19074 1.000 27.41453  ? 205 HIS   A NE2 1 
ATOM   1685 N N   . GLY   A 1 206 ? -38.63072  -28.91847 -119.91901 1.000 18.79449  ? 206 GLY   A N   1 
ATOM   1686 C CA  . GLY   A 1 206 ? -39.47488  -27.88701 -119.35357 1.000 18.29505  ? 206 GLY   A CA  1 
ATOM   1687 C C   . GLY   A 1 206 ? -38.83072  -26.52657 -119.40183 1.000 18.74559  ? 206 GLY   A C   1 
ATOM   1688 O O   . GLY   A 1 206 ? -37.60556  -26.38780 -119.49969 1.000 17.25357  ? 206 GLY   A O   1 
ATOM   1689 N N   . ILE   A 1 207 ? -39.68218  -25.51361 -119.33376 1.000 16.08303  ? 207 ILE   A N   1 
ATOM   1690 C CA  . ILE   A 1 207 ? -39.24792  -24.13045 -119.21399 1.000 15.71317  ? 207 ILE   A CA  1 
ATOM   1691 C C   . ILE   A 1 207 ? -39.72575  -23.61622 -117.86296 1.000 13.76794  ? 207 ILE   A C   1 
ATOM   1692 O O   . ILE   A 1 207 ? -40.89560  -23.80078 -117.48943 1.000 9.14116   ? 207 ILE   A O   1 
ATOM   1693 C CB  . ILE   A 1 207 ? -39.77970  -23.25902 -120.37081 1.000 20.67382  ? 207 ILE   A CB  1 
ATOM   1694 C CG1 . ILE   A 1 207 ? -38.99802  -23.54567 -121.65066 1.000 17.41720  ? 207 ILE   A CG1 1 
ATOM   1695 C CG2 . ILE   A 1 207 ? -39.67274  -21.77068 -120.03827 1.000 13.49632  ? 207 ILE   A CG2 1 
ATOM   1696 C CD1 . ILE   A 1 207 ? -39.63350  -22.95684 -122.88537 1.000 17.21933  ? 207 ILE   A CD1 1 
ATOM   1697 N N   . GLY   A 1 208 ? -38.81657  -22.99476 -117.13081 1.000 10.73729  ? 208 GLY   A N   1 
ATOM   1698 C CA  . GLY   A 1 208 ? -39.16379  -22.35998 -115.88606 1.000 11.76715  ? 208 GLY   A CA  1 
ATOM   1699 C C   . GLY   A 1 208 ? -39.37259  -20.87694 -116.08142 1.000 16.64901  ? 208 GLY   A C   1 
ATOM   1700 O O   . GLY   A 1 208 ? -38.43827  -20.14235 -116.42457 1.000 15.09529  ? 208 GLY   A O   1 
ATOM   1701 N N   . MET   A 1 209 ? -40.60683  -20.43495 -115.87928 1.000 12.36900  ? 209 MET   A N   1 
ATOM   1702 C CA  . MET   A 1 209 ? -40.95319  -19.02161 -115.92323 1.000 15.63832  ? 209 MET   A CA  1 
ATOM   1703 C C   . MET   A 1 209 ? -40.78265  -18.46163 -114.51743 1.000 18.06433  ? 209 MET   A C   1 
ATOM   1704 O O   . MET   A 1 209 ? -41.55733  -18.79207 -113.61379 1.000 18.73198  ? 209 MET   A O   1 
ATOM   1705 C CB  . MET   A 1 209 ? -42.38299  -18.84104 -116.42287 1.000 16.11773  ? 209 MET   A CB  1 
ATOM   1706 C CG  . MET   A 1 209 ? -42.59181  -19.26167 -117.88052 1.000 12.70967  ? 209 MET   A CG  1 
ATOM   1707 S SD  . MET   A 1 209 ? -44.33526  -19.30079 -118.39158 1.000 14.17099  ? 209 MET   A SD  1 
ATOM   1708 C CE  . MET   A 1 209 ? -44.73348  -17.55388 -118.31171 1.000 16.51118  ? 209 MET   A CE  1 
ATOM   1709 N N   . GLN   A 1 210 ? -39.76354  -17.62612 -114.32628 1.000 13.24109  ? 210 GLN   A N   1 
ATOM   1710 C CA  . GLN   A 1 210 ? -39.46747  -17.14900 -112.98207 1.000 16.93606  ? 210 GLN   A CA  1 
ATOM   1711 C C   . GLN   A 1 210 ? -40.59743  -16.29074 -112.43224 1.000 17.73991  ? 210 GLN   A C   1 
ATOM   1712 O O   . GLN   A 1 210 ? -40.92746  -16.38349 -111.24302 1.000 13.11411  ? 210 GLN   A O   1 
ATOM   1713 C CB  . GLN   A 1 210 ? -38.14311  -16.37790 -112.96744 1.000 16.15901  ? 210 GLN   A CB  1 
ATOM   1714 C CG  . GLN   A 1 210 ? -36.93409  -17.28707 -112.92008 1.000 13.50048  ? 210 GLN   A CG  1 
ATOM   1715 C CD  . GLN   A 1 210 ? -35.64195  -16.53390 -112.78570 1.000 16.32871  ? 210 GLN   A CD  1 
ATOM   1716 O OE1 . GLN   A 1 210 ? -35.60771  -15.43857 -112.23763 1.000 17.01611  ? 210 GLN   A OE1 1 
ATOM   1717 N NE2 . GLN   A 1 210 ? -34.56035  -17.11850 -113.28661 1.000 16.25916  ? 210 GLN   A NE2 1 
ATOM   1718 N N   . ALA   A 1 211 ? -41.18640  -15.43545 -113.27307 1.000 14.71733  ? 211 ALA   A N   1 
ATOM   1719 C CA  . ALA   A 1 211 ? -42.31409  -14.59627 -112.87627 1.000 11.59563  ? 211 ALA   A CA  1 
ATOM   1720 C C   . ALA   A 1 211 ? -41.95810  -13.66177 -111.71076 1.000 18.65473  ? 211 ALA   A C   1 
ATOM   1721 O O   . ALA   A 1 211 ? -42.69178  -13.55811 -110.72105 1.000 15.79970  ? 211 ALA   A O   1 
ATOM   1722 C CB  . ALA   A 1 211 ? -43.53070  -15.45537 -112.53372 1.000 11.59972  ? 211 ALA   A CB  1 
ATOM   1723 N N   . HIS   A 1 212 ? -40.82259  -12.96275 -111.83277 1.000 11.66366  ? 212 HIS   A N   1 
ATOM   1724 C CA  . HIS   A 1 212 ? -40.49951  -11.88295 -110.89558 1.000 15.54266  ? 212 HIS   A CA  1 
ATOM   1725 C C   . HIS   A 1 212 ? -41.18665  -10.63850 -111.43838 1.000 18.22297  ? 212 HIS   A C   1 
ATOM   1726 O O   . HIS   A 1 212 ? -40.61886  -9.85056  -112.19311 1.000 14.97560  ? 212 HIS   A O   1 
ATOM   1727 C CB  . HIS   A 1 212 ? -38.99165  -11.71689 -110.72064 1.000 13.47642  ? 212 HIS   A CB  1 
ATOM   1728 C CG  . HIS   A 1 212 ? -38.36182  -12.83380 -109.94497 1.000 19.96983  ? 212 HIS   A CG  1 
ATOM   1729 N ND1 . HIS   A 1 212 ? -38.80056  -13.20683 -108.69105 1.000 18.48059  ? 212 HIS   A ND1 1 
ATOM   1730 C CD2 . HIS   A 1 212 ? -37.35017  -13.68111 -110.25583 1.000 17.67127  ? 212 HIS   A CD2 1 
ATOM   1731 C CE1 . HIS   A 1 212 ? -38.07956  -14.22960 -108.26024 1.000 15.56059  ? 212 HIS   A CE1 1 
ATOM   1732 N NE2 . HIS   A 1 212 ? -37.19420  -14.53558 -109.19134 1.000 13.33594  ? 212 HIS   A NE2 1 
ATOM   1733 N N   . TRP   A 1 213 ? -42.44324  -10.48012 -111.05864 1.000 18.03399  ? 213 TRP   A N   1 
ATOM   1734 C CA  . TRP   A 1 213 ? -43.35958  -9.57485  -111.72228 1.000 16.71129  ? 213 TRP   A CA  1 
ATOM   1735 C C   . TRP   A 1 213 ? -43.62125  -8.33633  -110.87323 1.000 24.12206  ? 213 TRP   A C   1 
ATOM   1736 O O   . TRP   A 1 213 ? -43.29999  -8.27905  -109.67553 1.000 22.65059  ? 213 TRP   A O   1 
ATOM   1737 C CB  . TRP   A 1 213 ? -44.66030  -10.31545 -112.03853 1.000 14.57007  ? 213 TRP   A CB  1 
ATOM   1738 C CG  . TRP   A 1 213 ? -44.48701  -11.32555 -113.13645 1.000 17.50836  ? 213 TRP   A CG  1 
ATOM   1739 C CD1 . TRP   A 1 213 ? -43.42132  -11.42941 -114.00828 1.000 14.21407  ? 213 TRP   A CD1 1 
ATOM   1740 C CD2 . TRP   A 1 213 ? -45.40855  -12.36234 -113.50295 1.000 15.40588  ? 213 TRP   A CD2 1 
ATOM   1741 N NE1 . TRP   A 1 213 ? -43.63871  -12.46107 -114.89355 1.000 15.53817  ? 213 TRP   A NE1 1 
ATOM   1742 C CE2 . TRP   A 1 213 ? -44.84208  -13.05602 -114.60269 1.000 16.66425  ? 213 TRP   A CE2 1 
ATOM   1743 C CE3 . TRP   A 1 213 ? -46.65938  -12.77002 -113.01277 1.000 16.15038  ? 213 TRP   A CE3 1 
ATOM   1744 C CZ2 . TRP   A 1 213 ? -45.48306  -14.13791 -115.21636 1.000 13.47407  ? 213 TRP   A CZ2 1 
ATOM   1745 C CZ3 . TRP   A 1 213 ? -47.29151  -13.85421 -113.61379 1.000 16.10805  ? 213 TRP   A CZ3 1 
ATOM   1746 C CH2 . TRP   A 1 213 ? -46.69850  -14.52858 -114.70237 1.000 19.61840  ? 213 TRP   A CH2 1 
ATOM   1747 N N   . SER   A 1 214 ? -44.19449  -7.32919  -111.52439 1.000 14.55189  ? 214 SER   A N   1 
ATOM   1748 C CA  . SER   A 1 214 ? -44.60714  -6.09048  -110.88137 1.000 15.91020  ? 214 SER   A CA  1 
ATOM   1749 C C   . SER   A 1 214 ? -46.12682  -5.99539  -110.95030 1.000 17.62764  ? 214 SER   A C   1 
ATOM   1750 O O   . SER   A 1 214 ? -46.79931  -6.86795  -111.51084 1.000 16.29388  ? 214 SER   A O   1 
ATOM   1751 C CB  . SER   A 1 214 ? -43.93063  -4.88502  -111.54239 1.000 18.85217  ? 214 SER   A CB  1 
ATOM   1752 O OG  . SER   A 1 214 ? -44.51785  -4.56755  -112.79944 1.000 17.55295  ? 214 SER   A OG  1 
ATOM   1753 N N   . LEU   A 1 215 ? -46.68124  -4.93091  -110.36256 1.000 21.86879  ? 215 LEU   A N   1 
ATOM   1754 C CA  . LEU   A 1 215 ? -48.13407  -4.75987  -110.40067 1.000 16.75674  ? 215 LEU   A CA  1 
ATOM   1755 C C   . LEU   A 1 215 ? -48.63418  -4.55919  -111.83022 1.000 22.12870  ? 215 LEU   A C   1 
ATOM   1756 O O   . LEU   A 1 215 ? -49.77046  -4.93431  -112.14406 1.000 18.44551  ? 215 LEU   A O   1 
ATOM   1757 C CB  . LEU   A 1 215 ? -48.54907  -3.58458  -109.51537 1.000 14.55293  ? 215 LEU   A CB  1 
ATOM   1758 C CG  . LEU   A 1 215 ? -48.40792  -3.80109  -108.00885 1.000 16.73095  ? 215 LEU   A CG  1 
ATOM   1759 C CD1 . LEU   A 1 215 ? -48.81580  -2.58017  -107.21782 1.000 13.56163  ? 215 LEU   A CD1 1 
ATOM   1760 C CD2 . LEU   A 1 215 ? -49.23398  -4.97190  -107.58525 1.000 17.96526  ? 215 LEU   A CD2 1 
ATOM   1761 N N   . THR   A 1 216 ? -47.78224  -4.01174  -112.71231 1.000 20.60292  ? 216 THR   A N   1 
ATOM   1762 C CA  . THR   A 1 216 ? -48.11961  -3.64139  -114.08373 1.000 17.15266  ? 216 THR   A CA  1 
ATOM   1763 C C   . THR   A 1 216 ? -47.53303  -4.56093  -115.14465 1.000 21.93085  ? 216 THR   A C   1 
ATOM   1764 O O   . THR   A 1 216 ? -48.16718  -4.76095  -116.18208 1.000 22.54988  ? 216 THR   A O   1 
ATOM   1765 C CB  . THR   A 1 216 ? -47.63385  -2.21080  -114.37680 1.000 18.88378  ? 216 THR   A CB  1 
ATOM   1766 O OG1 . THR   A 1 216 ? -48.23573  -1.29781  -113.46018 1.000 23.54052  ? 216 THR   A OG1 1 
ATOM   1767 C CG2 . THR   A 1 216 ? -47.99130  -1.77797  -115.78599 1.000 19.64926  ? 216 THR   A CG2 1 
ATOM   1768 N N   . ARG   A 1 217 ? -46.33829  -5.11596  -114.92193 1.000 19.98853  ? 217 ARG   A N   1 
ATOM   1769 C CA  . ARG   A 1 217 ? -45.56806  -5.78989  -115.96050 1.000 17.83362  ? 217 ARG   A CA  1 
ATOM   1770 C C   . ARG   A 1 217 ? -45.25373  -7.22479  -115.56512 1.000 17.66144  ? 217 ARG   A C   1 
ATOM   1771 O O   . ARG   A 1 217 ? -44.90777  -7.48992  -114.40894 1.000 23.38705  ? 217 ARG   A O   1 
ATOM   1772 C CB  . ARG   A 1 217 ? -44.22770  -5.07190  -116.23337 1.000 11.84015  ? 217 ARG   A CB  1 
ATOM   1773 C CG  . ARG   A 1 217 ? -44.31821  -3.59812  -116.48712 1.000 10.82065  ? 217 ARG   A CG  1 
ATOM   1774 C CD  . ARG   A 1 217 ? -43.06545  -3.15155  -117.17964 1.000 15.57174  ? 217 ARG   A CD  1 
ATOM   1775 N NE  . ARG   A 1 217 ? -42.95359  -3.75623  -118.50629 1.000 22.78646  ? 217 ARG   A NE  1 
ATOM   1776 C CZ  . ARG   A 1 217 ? -41.88329  -3.65004  -119.28629 1.000 25.84743  ? 217 ARG   A CZ  1 
ATOM   1777 N NH1 . ARG   A 1 217 ? -40.83134  -2.97403  -118.86031 1.000 27.95643  ? 217 ARG   A NH1 1 
ATOM   1778 N NH2 . ARG   A 1 217 ? -41.86393  -4.20990  -120.48932 1.000 19.59372  ? 217 ARG   A NH2 1 
ATOM   1779 N N   . PRO   A 1 218 ? -45.33628  -8.16974  -116.49980 1.000 18.73384  ? 218 PRO   A N   1 
ATOM   1780 C CA  . PRO   A 1 218 ? -45.85567  -7.99367  -117.85106 1.000 17.05017  ? 218 PRO   A CA  1 
ATOM   1781 C C   . PRO   A 1 218 ? -47.39495  -7.95593  -117.82022 1.000 28.06777  ? 218 PRO   A C   1 
ATOM   1782 O O   . PRO   A 1 218 ? -47.99492  -8.30251  -116.78296 1.000 18.20604  ? 218 PRO   A O   1 
ATOM   1783 C CB  . PRO   A 1 218 ? -45.33945  -9.23755  -118.57365 1.000 17.41818  ? 218 PRO   A CB  1 
ATOM   1784 C CG  . PRO   A 1 218 ? -45.38247  -10.28813 -117.51198 1.000 20.06225  ? 218 PRO   A CG  1 
ATOM   1785 C CD  . PRO   A 1 218 ? -44.96436  -9.57269  -116.23935 1.000 18.48273  ? 218 PRO   A CD  1 
ATOM   1786 N N   . SER   A 1 219 ? -48.01959  -7.53247  -118.92012 1.000 18.47972  ? 219 SER   A N   1 
ATOM   1787 C CA  . SER   A 1 219 ? -49.47158  -7.52810  -118.98235 1.000 19.85821  ? 219 SER   A CA  1 
ATOM   1788 C C   . SER   A 1 219 ? -50.00277  -8.95219  -118.99618 1.000 17.18259  ? 219 SER   A C   1 
ATOM   1789 O O   . SER   A 1 219 ? -49.28824  -9.90753  -119.32070 1.000 20.64522  ? 219 SER   A O   1 
ATOM   1790 C CB  . SER   A 1 219 ? -49.96441  -6.80583  -120.23170 1.000 14.94833  ? 219 SER   A CB  1 
ATOM   1791 O OG  . SER   A 1 219 ? -49.53313  -7.49674  -121.38555 1.000 16.18312  ? 219 SER   A OG  1 
ATOM   1792 N N   . LEU   A 1 220 ? -51.28947  -9.07920  -118.66438 1.000 20.83518  ? 220 LEU   A N   1 
ATOM   1793 C CA  . LEU   A 1 220 ? -51.95673  -10.37372 -118.75452 1.000 19.15889  ? 220 LEU   A CA  1 
ATOM   1794 C C   . LEU   A 1 220 ? -51.87931  -10.93997 -120.16171 1.000 19.17287  ? 220 LEU   A C   1 
ATOM   1795 O O   . LEU   A 1 220 ? -51.72195  -12.15089 -120.33627 1.000 23.78779  ? 220 LEU   A O   1 
ATOM   1796 C CB  . LEU   A 1 220 ? -53.41299  -10.25076 -118.32355 1.000 18.32073  ? 220 LEU   A CB  1 
ATOM   1797 C CG  . LEU   A 1 220 ? -53.64784  -10.06017 -116.82993 1.000 30.91219  ? 220 LEU   A CG  1 
ATOM   1798 C CD1 . LEU   A 1 220 ? -55.13477  -9.75996  -116.57577 1.000 20.98736  ? 220 LEU   A CD1 1 
ATOM   1799 C CD2 . LEU   A 1 220 ? -53.16422  -11.29795 -116.04732 1.000 19.96279  ? 220 LEU   A CD2 1 
ATOM   1800 N N   . ASP   A 1 221 ? -52.00468  -10.08485 -121.18049 1.000 19.74848  ? 221 ASP   A N   1 
ATOM   1801 C CA  . ASP   A 1 221 ? -51.87003  -10.55955 -122.55770 1.000 24.42498  ? 221 ASP   A CA  1 
ATOM   1802 C C   . ASP   A 1 221 ? -50.45246  -11.05765 -122.83721 1.000 21.59840  ? 221 ASP   A C   1 
ATOM   1803 O O   . ASP   A 1 221 ? -50.26577  -12.01668 -123.59407 1.000 22.66302  ? 221 ASP   A O   1 
ATOM   1804 C CB  . ASP   A 1 221 ? -52.25779  -9.45579  -123.55295 1.000 25.69434  ? 221 ASP   A CB  1 
ATOM   1805 C CG  . ASP   A 1 221 ? -53.78137  -9.23857  -123.65543 1.000 28.30725  ? 221 ASP   A CG  1 
ATOM   1806 O OD1 . ASP   A 1 221 ? -54.57459  -10.07115 -123.14465 1.000 26.22365  ? 221 ASP   A OD1 1 
ATOM   1807 O OD2 . ASP   A 1 221 ? -54.18342  -8.20662  -124.24106 1.000 30.33550  ? 221 ASP   A OD2 1 
ATOM   1808 N N   . GLU   A 1 222 ? -49.43752  -10.42657 -122.23395 1.000 21.51112  ? 222 GLU   A N   1 
ATOM   1809 C CA  . GLU   A 1 222 ? -48.07091  -10.89651 -122.44921 1.000 23.24423  ? 222 GLU   A CA  1 
ATOM   1810 C C   . GLU   A 1 222 ? -47.82912  -12.23192 -121.75062 1.000 19.58393  ? 222 GLU   A C   1 
ATOM   1811 O O   . GLU   A 1 222 ? -47.09184  -13.07917 -122.26355 1.000 19.94715  ? 222 GLU   A O   1 
ATOM   1812 C CB  . GLU   A 1 222 ? -47.05751  -9.85036  -121.98061 1.000 20.42672  ? 222 GLU   A CB  1 
ATOM   1813 C CG  . GLU   A 1 222 ? -46.96841  -8.61955  -122.88797 1.000 21.74752  ? 222 GLU   A CG  1 
ATOM   1814 C CD  . GLU   A 1 222 ? -46.04069  -7.52916  -122.33347 1.000 26.10842  ? 222 GLU   A CD  1 
ATOM   1815 O OE1 . GLU   A 1 222 ? -45.98304  -7.35280  -121.09249 1.000 18.30622  ? 222 GLU   A OE1 1 
ATOM   1816 O OE2 . GLU   A 1 222 ? -45.37093  -6.84054  -123.14067 1.000 26.87605  ? 222 GLU   A OE2 1 
ATOM   1817 N N   . ILE   A 1 223 ? -48.43566  -12.43678 -120.58149 1.000 13.72952  ? 223 ILE   A N   1 
ATOM   1818 C CA  . ILE   A 1 223 ? -48.29217  -13.71132 -119.88723 1.000 15.97795  ? 223 ILE   A CA  1 
ATOM   1819 C C   . ILE   A 1 223 ? -48.96385  -14.81711 -120.68857 1.000 21.86510  ? 223 ILE   A C   1 
ATOM   1820 O O   . ILE   A 1 223 ? -48.38856  -15.88757 -120.91421 1.000 15.07000  ? 223 ILE   A O   1 
ATOM   1821 C CB  . ILE   A 1 223 ? -48.88010  -13.62134 -118.46623 1.000 17.71152  ? 223 ILE   A CB  1 
ATOM   1822 C CG1 . ILE   A 1 223 ? -48.17279  -12.55202 -117.63137 1.000 18.79949  ? 223 ILE   A CG1 1 
ATOM   1823 C CG2 . ILE   A 1 223 ? -48.83108  -14.96371 -117.77168 1.000 15.98613  ? 223 ILE   A CG2 1 
ATOM   1824 C CD1 . ILE   A 1 223 ? -48.94591  -12.22724 -116.34636 1.000 15.19137  ? 223 ILE   A CD1 1 
ATOM   1825 N N   . ARG   A 1 224 ? -50.19685  -14.56809 -121.13454 1.000 19.67382  ? 224 ARG   A N   1 
ATOM   1826 C CA  . ARG   A 1 224 ? -50.90099  -15.54680 -121.94961 1.000 20.30452  ? 224 ARG   A CA  1 
ATOM   1827 C C   . ARG   A 1 224 ? -50.10086  -15.90102 -123.20121 1.000 17.72584  ? 224 ARG   A C   1 
ATOM   1828 O O   . ARG   A 1 224 ? -49.90376  -17.07987 -123.51228 1.000 22.63561  ? 224 ARG   A O   1 
ATOM   1829 C CB  . ARG   A 1 224 ? -52.28451  -15.01825 -122.31413 1.000 18.35136  ? 224 ARG   A CB  1 
ATOM   1830 C CG  . ARG   A 1 224 ? -53.04951  -15.95271 -123.23653 1.000 24.89067  ? 224 ARG   A CG  1 
ATOM   1831 C CD  . ARG   A 1 224 ? -54.33106  -15.32119 -123.73225 1.000 18.62348  ? 224 ARG   A CD  1 
ATOM   1832 N NE  . ARG   A 1 224 ? -55.25303  -14.95373 -122.65616 1.000 20.77109  ? 224 ARG   A NE  1 
ATOM   1833 C CZ  . ARG   A 1 224 ? -56.13753  -15.78635 -122.11542 1.000 19.81973  ? 224 ARG   A CZ  1 
ATOM   1834 N NH1 . ARG   A 1 224 ? -56.19315  -17.03866 -122.53585 1.000 19.01423  ? 224 ARG   A NH1 1 
ATOM   1835 N NH2 . ARG   A 1 224 ? -56.95449  -15.37685 -121.15237 1.000 20.53926  ? 224 ARG   A NH2 1 
ATOM   1836 N N   . ALA   A 1 225 ? -49.60243  -14.89590 -123.91445 1.000 11.73698  ? 225 ALA   A N   1 
ATOM   1837 C CA  . ALA   A 1 225 ? -48.85779  -15.17591 -125.13936 1.000 21.65159  ? 225 ALA   A CA  1 
ATOM   1838 C C   . ALA   A 1 225 ? -47.58844  -15.98247 -124.85628 1.000 22.34377  ? 225 ALA   A C   1 
ATOM   1839 O O   . ALA   A 1 225 ? -47.23755  -16.88787 -125.62477 1.000 20.71958  ? 225 ALA   A O   1 
ATOM   1840 C CB  . ALA   A 1 225 ? -48.52623  -13.86844 -125.86085 1.000 15.35318  ? 225 ALA   A CB  1 
ATOM   1841 N N   . ALA   A 1 226 ? -46.89634  -15.68435 -123.75082 1.000 16.56053  ? 226 ALA   A N   1 
ATOM   1842 C CA  . ALA   A 1 226 ? -45.67934  -16.42207 -123.41731 1.000 17.12945  ? 226 ALA   A CA  1 
ATOM   1843 C C   . ALA   A 1 226 ? -45.99450  -17.87764 -123.08547 1.000 16.76948  ? 226 ALA   A C   1 
ATOM   1844 O O   . ALA   A 1 226 ? -45.32580  -18.79677 -123.57908 1.000 19.75927  ? 226 ALA   A O   1 
ATOM   1845 C CB  . ALA   A 1 226 ? -44.94566  -15.73936 -122.25392 1.000 13.02666  ? 226 ALA   A CB  1 
ATOM   1846 N N   . ILE   A 1 227 ? -47.01495  -18.10467 -122.24950 1.000 15.61545  ? 227 ILE   A N   1 
ATOM   1847 C CA  . ILE   A 1 227 ? -47.44572  -19.46361 -121.91985 1.000 14.98767  ? 227 ILE   A CA  1 
ATOM   1848 C C   . ILE   A 1 227 ? -47.74020  -20.25192 -123.19366 1.000 19.03188  ? 227 ILE   A C   1 
ATOM   1849 O O   . ILE   A 1 227 ? -47.26393  -21.37883 -123.38607 1.000 20.92851  ? 227 ILE   A O   1 
ATOM   1850 C CB  . ILE   A 1 227 ? -48.67666  -19.41936 -120.99896 1.000 12.85800  ? 227 ILE   A CB  1 
ATOM   1851 C CG1 . ILE   A 1 227 ? -48.33276  -18.87660 -119.61668 1.000 11.22737  ? 227 ILE   A CG1 1 
ATOM   1852 C CG2 . ILE   A 1 227 ? -49.32638  -20.79700 -120.88112 1.000 14.90626  ? 227 ILE   A CG2 1 
ATOM   1853 C CD1 . ILE   A 1 227 ? -49.60207  -18.56353 -118.77509 1.000 14.96757  ? 227 ILE   A CD1 1 
ATOM   1854 N N   . GLU   A 1 228 ? -48.52422  -19.66171 -124.09046 1.000 24.01460  ? 228 GLU   A N   1 
ATOM   1855 C CA  . GLU   A 1 228 ? -48.88796  -20.36129 -125.31689 1.000 27.41343  ? 228 GLU   A CA  1 
ATOM   1856 C C   . GLU   A 1 228 ? -47.68177  -20.55440 -126.22739 1.000 20.69622  ? 228 GLU   A C   1 
ATOM   1857 O O   . GLU   A 1 228 ? -47.54884  -21.59923 -126.87487 1.000 22.82272  ? 228 GLU   A O   1 
ATOM   1858 C CB  . GLU   A 1 228 ? -50.00178  -19.60372 -126.02661 1.000 20.25373  ? 228 GLU   A CB  1 
ATOM   1859 C CG  . GLU   A 1 228 ? -51.28557  -20.36693 -125.99975 1.000 35.56026  ? 228 GLU   A CG  1 
ATOM   1860 C CD  . GLU   A 1 228 ? -52.46474  -19.47982 -126.22592 1.000 48.92659  ? 228 GLU   A CD  1 
ATOM   1861 O OE1 . GLU   A 1 228 ? -53.60658  -19.94685 -126.01086 1.000 41.17271  ? 228 GLU   A OE1 1 
ATOM   1862 O OE2 . GLU   A 1 228 ? -52.23773  -18.31474 -126.62161 1.000 52.55856  ? 228 GLU   A OE2 1 
ATOM   1863 N N   . ARG   A 1 229 ? -46.78000  -19.57198 -126.26889 1.000 20.50422  ? 229 ARG   A N   1 
ATOM   1864 C CA  . ARG   A 1 229 ? -45.57342  -19.70595 -127.07912 1.000 22.06961  ? 229 ARG   A CA  1 
ATOM   1865 C C   . ARG   A 1 229 ? -44.69942  -20.85698 -126.57962 1.000 25.70287  ? 229 ARG   A C   1 
ATOM   1866 O O   . ARG   A 1 229 ? -44.24273  -21.69927 -127.36655 1.000 20.29835  ? 229 ARG   A O   1 
ATOM   1867 C CB  . ARG   A 1 229 ? -44.80443  -18.38723 -127.06381 1.000 26.35486  ? 229 ARG   A CB  1 
ATOM   1868 C CG  . ARG   A 1 229 ? -43.66967  -18.29760 -128.05147 1.000 20.94957  ? 229 ARG   A CG  1 
ATOM   1869 C CD  . ARG   A 1 229 ? -44.16881  -18.40379 -129.48528 1.000 23.00733  ? 229 ARG   A CD  1 
ATOM   1870 N NE  . ARG   A 1 229 ? -43.15671  -17.91095 -130.41389 1.000 19.79042  ? 229 ARG   A NE  1 
ATOM   1871 C CZ  . ARG   A 1 229 ? -43.01497  -18.33717 -131.65950 1.000 22.51829  ? 229 ARG   A CZ  1 
ATOM   1872 N NH1 . ARG   A 1 229 ? -43.83768  -19.26290 -132.13647 1.000 19.90584  ? 229 ARG   A NH1 1 
ATOM   1873 N NH2 . ARG   A 1 229 ? -42.05637  -17.83199 -132.43004 1.000 15.86688  ? 229 ARG   A NH2 1 
ATOM   1874 N N   . TYR   A 1 230 ? -44.46197  -20.91014 -125.26639 1.000 18.48952  ? 230 TYR   A N   1 
ATOM   1875 C CA  . TYR   A 1 230 ? -43.66199  -21.99128 -124.69756 1.000 18.63280  ? 230 TYR   A CA  1 
ATOM   1876 C C   . TYR   A 1 230 ? -44.38431  -23.33368 -124.79942 1.000 17.91145  ? 230 TYR   A C   1 
ATOM   1877 O O   . TYR   A 1 230 ? -43.79399  -24.32801 -125.23259 1.000 22.64989  ? 230 TYR   A O   1 
ATOM   1878 C CB  . TYR   A 1 230 ? -43.30935  -21.67098 -123.24322 1.000 14.85726  ? 230 TYR   A CB  1 
ATOM   1879 C CG  . TYR   A 1 230 ? -42.48084  -20.40910 -123.09614 1.000 17.92710  ? 230 TYR   A CG  1 
ATOM   1880 C CD1 . TYR   A 1 230 ? -41.54899  -20.06013 -124.06451 1.000 12.34406  ? 230 TYR   A CD1 1 
ATOM   1881 C CD2 . TYR   A 1 230 ? -42.63663  -19.56315 -121.99229 1.000 12.02257  ? 230 TYR   A CD2 1 
ATOM   1882 C CE1 . TYR   A 1 230 ? -40.78736  -18.91194 -123.93650 1.000 17.29840  ? 230 TYR   A CE1 1 
ATOM   1883 C CE2 . TYR   A 1 230 ? -41.88431  -18.40285 -121.86066 1.000 11.30663  ? 230 TYR   A CE2 1 
ATOM   1884 C CZ  . TYR   A 1 230 ? -40.96286  -18.08236 -122.83739 1.000 15.23242  ? 230 TYR   A CZ  1 
ATOM   1885 O OH  . TYR   A 1 230 ? -40.20018  -16.94568 -122.72405 1.000 14.34168  ? 230 TYR   A OH  1 
ATOM   1886 N N   . ALA   A 1 231 ? -45.66167  -23.38920 -124.40112 1.000 15.34604  ? 231 ALA   A N   1 
ATOM   1887 C CA  . ALA   A 1 231 ? -46.38697  -24.65577 -124.46377 1.000 20.95413  ? 231 ALA   A CA  1 
ATOM   1888 C C   . ALA   A 1 231 ? -46.39609  -25.23684 -125.87644 1.000 22.07308  ? 231 ALA   A C   1 
ATOM   1889 O O   . ALA   A 1 231 ? -46.46594  -26.46117 -126.03920 1.000 23.72106  ? 231 ALA   A O   1 
ATOM   1890 C CB  . ALA   A 1 231 ? -47.82034  -24.48545 -123.95104 1.000 13.64442  ? 231 ALA   A CB  1 
ATOM   1891 N N   . SER   A 1 232 ? -46.28832  -24.39184 -126.90827 1.000 20.83832  ? 232 SER   A N   1 
ATOM   1892 C CA  . SER   A 1 232 ? -46.32184  -24.91188 -128.27526 1.000 21.07669  ? 232 SER   A CA  1 
ATOM   1893 C C   . SER   A 1 232 ? -45.10451  -25.76947 -128.58743 1.000 21.00658  ? 232 SER   A C   1 
ATOM   1894 O O   . SER   A 1 232 ? -45.15745  -26.57677 -129.51807 1.000 21.48183  ? 232 SER   A O   1 
ATOM   1895 C CB  . SER   A 1 232 ? -46.44870  -23.77253 -129.30069 1.000 13.68131  ? 232 SER   A CB  1 
ATOM   1896 O OG  . SER   A 1 232 ? -45.26300  -22.98642 -129.39510 1.000 23.73846  ? 232 SER   A OG  1 
ATOM   1897 N N   . LEU   A 1 233 ? -44.02229  -25.62841 -127.81908 1.000 23.45876  ? 233 LEU   A N   1 
ATOM   1898 C CA  . LEU   A 1 233 ? -42.82658  -26.43538 -128.00065 1.000 17.12930  ? 233 LEU   A CA  1 
ATOM   1899 C C   . LEU   A 1 233 ? -42.97249  -27.85223 -127.45418 1.000 20.82234  ? 233 LEU   A C   1 
ATOM   1900 O O   . LEU   A 1 233 ? -42.08542  -28.67788 -127.68342 1.000 30.04544  ? 233 LEU   A O   1 
ATOM   1901 C CB  . LEU   A 1 233 ? -41.63849  -25.75834 -127.32787 1.000 18.66117  ? 233 LEU   A CB  1 
ATOM   1902 C CG  . LEU   A 1 233 ? -41.09711  -24.49894 -128.00502 1.000 27.81563  ? 233 LEU   A CG  1 
ATOM   1903 C CD1 . LEU   A 1 233 ? -39.99461  -23.84069 -127.16302 1.000 23.45490  ? 233 LEU   A CD1 1 
ATOM   1904 C CD2 . LEU   A 1 233 ? -40.57121  -24.84170 -129.38272 1.000 26.82574  ? 233 LEU   A CD2 1 
ATOM   1905 N N   . GLY   A 1 234 ? -44.05763  -28.15980 -126.74921 1.000 21.74539  ? 234 GLY   A N   1 
ATOM   1906 C CA  . GLY   A 1 234 ? -44.20877  -29.45703 -126.12751 1.000 18.55918  ? 234 GLY   A CA  1 
ATOM   1907 C C   . GLY   A 1 234 ? -43.54464  -29.61302 -124.77193 1.000 28.04018  ? 234 GLY   A C   1 
ATOM   1908 O O   . GLY   A 1 234 ? -43.56271  -30.72136 -124.22432 1.000 38.02862  ? 234 GLY   A O   1 
ATOM   1909 N N   . VAL   A 1 235 ? -42.95350  -28.54944 -124.21052 1.000 22.24498  ? 235 VAL   A N   1 
ATOM   1910 C CA  . VAL   A 1 235 ? -42.34507  -28.62762 -122.88247 1.000 21.88835  ? 235 VAL   A CA  1 
ATOM   1911 C C   . VAL   A 1 235 ? -43.41903  -28.51372 -121.80227 1.000 26.08377  ? 235 VAL   A C   1 
ATOM   1912 O O   . VAL   A 1 235 ? -44.52252  -28.00350 -122.02420 1.000 22.08709  ? 235 VAL   A O   1 
ATOM   1913 C CB  . VAL   A 1 235 ? -41.29223  -27.52517 -122.71150 1.000 20.37449  ? 235 VAL   A CB  1 
ATOM   1914 C CG1 . VAL   A 1 235 ? -40.21452  -27.65881 -123.76777 1.000 23.38262  ? 235 VAL   A CG1 1 
ATOM   1915 C CG2 . VAL   A 1 235 ? -41.96821  -26.15698 -122.80316 1.000 25.81672  ? 235 VAL   A CG2 1 
ATOM   1916 N N   . VAL   A 1 236 ? -43.08031  -28.95923 -120.59712 1.000 19.85761  ? 236 VAL   A N   1 
ATOM   1917 C CA  . VAL   A 1 236 ? -43.91421  -28.61819 -119.45203 1.000 24.26882  ? 236 VAL   A CA  1 
ATOM   1918 C C   . VAL   A 1 236 ? -43.50021  -27.24414 -118.94094 1.000 19.70870  ? 236 VAL   A C   1 
ATOM   1919 O O   . VAL   A 1 236 ? -42.36472  -26.79667 -119.13264 1.000 19.02869  ? 236 VAL   A O   1 
ATOM   1920 C CB  . VAL   A 1 236 ? -43.83195  -29.68714 -118.34239 1.000 23.25011  ? 236 VAL   A CB  1 
ATOM   1921 C CG1 . VAL   A 1 236 ? -43.88900  -31.06587 -118.94632 1.000 28.26997  ? 236 VAL   A CG1 1 
ATOM   1922 C CG2 . VAL   A 1 236 ? -42.57654  -29.52714 -117.53277 1.000 24.89992  ? 236 VAL   A CG2 1 
ATOM   1923 N N   . LEU   A 1 237 ? -44.43070  -26.56202 -118.28687 1.000 21.91308  ? 237 LEU   A N   1 
ATOM   1924 C CA  . LEU   A 1 237 ? -44.18978  -25.23463 -117.74055 1.000 18.86402  ? 237 LEU   A CA  1 
ATOM   1925 C C   . LEU   A 1 237 ? -44.26720  -25.27134 -116.21869 1.000 14.48861  ? 237 LEU   A C   1 
ATOM   1926 O O   . LEU   A 1 237 ? -45.24305  -25.78299 -115.65557 1.000 11.63262  ? 237 LEU   A O   1 
ATOM   1927 C CB  . LEU   A 1 237 ? -45.21161  -24.24184 -118.29114 1.000 16.85703  ? 237 LEU   A CB  1 
ATOM   1928 C CG  . LEU   A 1 237 ? -45.19392  -24.01702 -119.79345 1.000 19.93655  ? 237 LEU   A CG  1 
ATOM   1929 C CD1 . LEU   A 1 237 ? -46.18726  -22.91415 -120.19181 1.000 12.80782  ? 237 LEU   A CD1 1 
ATOM   1930 C CD2 . LEU   A 1 237 ? -43.76320  -23.68591 -120.22943 1.000 19.99465  ? 237 LEU   A CD2 1 
ATOM   1931 N N   . HIS   A 1 238 ? -43.23405  -24.74129 -115.56219 1.000 13.83799  ? 238 HIS   A N   1 
ATOM   1932 C CA  . HIS   A 1 238 ? -43.26547  -24.40820 -114.14239 1.000 13.91458  ? 238 HIS   A CA  1 
ATOM   1933 C C   . HIS   A 1 238 ? -43.15521  -22.89865 -113.99587 1.000 14.79000  ? 238 HIS   A C   1 
ATOM   1934 O O   . HIS   A 1 238 ? -42.34831  -22.26599 -114.68354 1.000 18.35084  ? 238 HIS   A O   1 
ATOM   1935 C CB  . HIS   A 1 238 ? -42.11605  -25.06147 -113.35941 1.000 14.04159  ? 238 HIS   A CB  1 
ATOM   1936 C CG  . HIS   A 1 238 ? -42.27885  -26.53189 -113.14099 1.000 12.64575  ? 238 HIS   A CG  1 
ATOM   1937 N ND1 . HIS   A 1 238 ? -41.42083  -27.26389 -112.34711 1.000 18.33327  ? 238 HIS   A ND1 1 
ATOM   1938 C CD2 . HIS   A 1 238 ? -43.18267  -27.41290 -113.62779 1.000 14.07409  ? 238 HIS   A CD2 1 
ATOM   1939 C CE1 . HIS   A 1 238 ? -41.80271  -28.53004 -112.34162 1.000 18.98387  ? 238 HIS   A CE1 1 
ATOM   1940 N NE2 . HIS   A 1 238 ? -42.87135  -28.64621 -113.10949 1.000 15.26216  ? 238 HIS   A NE2 1 
ATOM   1941 N N   . ILE   A 1 239 ? -43.97779  -22.32442 -113.11851 1.000 12.56096  ? 239 ILE   A N   1 
ATOM   1942 C CA  . ILE   A 1 239 ? -43.74689  -20.98167 -112.59557 1.000 14.88161  ? 239 ILE   A CA  1 
ATOM   1943 C C   . ILE   A 1 239 ? -42.83593  -21.14531 -111.38130 1.000 14.76830  ? 239 ILE   A C   1 
ATOM   1944 O O   . ILE   A 1 239 ? -43.21826  -21.78268 -110.39777 1.000 17.12334  ? 239 ILE   A O   1 
ATOM   1945 C CB  . ILE   A 1 239 ? -45.06721  -20.28933 -112.21348 1.000 13.80960  ? 239 ILE   A CB  1 
ATOM   1946 C CG1 . ILE   A 1 239 ? -46.15425  -20.53013 -113.26806 1.000 14.93992  ? 239 ILE   A CG1 1 
ATOM   1947 C CG2 . ILE   A 1 239 ? -44.84810  -18.80375 -111.95753 1.000 11.89188  ? 239 ILE   A CG2 1 
ATOM   1948 C CD1 . ILE   A 1 239 ? -45.92558  -19.84145 -114.58026 1.000 12.17029  ? 239 ILE   A CD1 1 
ATOM   1949 N N   . THR   A 1 240 ? -41.62354  -20.59700 -111.43696 1.000 14.93864  ? 240 THR   A N   1 
ATOM   1950 C CA  . THR   A 1 240 ? -40.60991  -21.05954 -110.49633 1.000 15.11227  ? 240 THR   A CA  1 
ATOM   1951 C C   . THR   A 1 240 ? -40.22602  -20.08416 -109.39412 1.000 15.17812  ? 240 THR   A C   1 
ATOM   1952 O O   . THR   A 1 240 ? -39.66147  -20.52599 -108.39174 1.000 16.89814  ? 240 THR   A O   1 
ATOM   1953 C CB  . THR   A 1 240 ? -39.33961  -21.45978 -111.24220 1.000 12.87736  ? 240 THR   A CB  1 
ATOM   1954 O OG1 . THR   A 1 240 ? -38.86724  -20.34540 -112.01017 1.000 21.84272  ? 240 THR   A OG1 1 
ATOM   1955 C CG2 . THR   A 1 240 ? -39.63361  -22.62704 -112.15460 1.000 9.21687   ? 240 THR   A CG2 1 
ATOM   1956 N N   . GLY   A 1 241 ? -40.50491  -18.79417 -109.53509 1.000 15.71758  ? 241 GLY   A N   1 
ATOM   1957 C CA  . GLY   A 1 241 ? -40.11703  -17.83606 -108.51221 1.000 13.92558  ? 241 GLY   A CA  1 
ATOM   1958 C C   . GLY   A 1 241 ? -41.10808  -16.69751 -108.36444 1.000 14.30467  ? 241 GLY   A C   1 
ATOM   1959 O O   . GLY   A 1 241 ? -40.71854  -15.53405 -108.20907 1.000 13.90776  ? 241 GLY   A O   1 
ATOM   1960 N N   . LEU   A 1 242 ? -42.39654  -17.02970 -108.40989 1.000 14.00678  ? 242 LEU   A N   1 
ATOM   1961 C CA  . LEU   A 1 242 ? -43.44529  -16.01440 -108.45526 1.000 13.88331  ? 242 LEU   A CA  1 
ATOM   1962 C C   . LEU   A 1 242 ? -43.38405  -15.07950 -107.24907 1.000 20.00454  ? 242 LEU   A C   1 
ATOM   1963 O O   . LEU   A 1 242 ? -43.33682  -15.52130 -106.08965 1.000 12.78089  ? 242 LEU   A O   1 
ATOM   1964 C CB  . LEU   A 1 242 ? -44.82202  -16.67847 -108.52983 1.000 9.91161   ? 242 LEU   A CB  1 
ATOM   1965 C CG  . LEU   A 1 242 ? -46.02805  -15.72384 -108.48970 1.000 17.65814  ? 242 LEU   A CG  1 
ATOM   1966 C CD1 . LEU   A 1 242 ? -46.04363  -14.80750 -109.71210 1.000 14.65629  ? 242 LEU   A CD1 1 
ATOM   1967 C CD2 . LEU   A 1 242 ? -47.34824  -16.50238 -108.36421 1.000 14.68579  ? 242 LEU   A CD2 1 
ATOM   1968 N N   . ASP   A 1 243 ? -43.34761  -13.78007 -107.54204 1.000 15.32833  ? 243 ASP   A N   1 
ATOM   1969 C CA  . ASP   A 1 243 ? -43.63951  -12.73703 -106.56947 1.000 14.95381  ? 243 ASP   A CA  1 
ATOM   1970 C C   . ASP   A 1 243 ? -44.13447  -11.51960 -107.33582 1.000 16.51557  ? 243 ASP   A C   1 
ATOM   1971 O O   . ASP   A 1 243 ? -43.94191  -11.39937 -108.54977 1.000 18.11648  ? 243 ASP   A O   1 
ATOM   1972 C CB  . ASP   A 1 243 ? -42.43836  -12.38430 -105.66580 1.000 13.74490  ? 243 ASP   A CB  1 
ATOM   1973 C CG  . ASP   A 1 243 ? -41.10354  -12.36266 -106.40434 1.000 17.38370  ? 243 ASP   A CG  1 
ATOM   1974 O OD1 . ASP   A 1 243 ? -41.05853  -12.04999 -107.61735 1.000 17.20509  ? 243 ASP   A OD1 1 
ATOM   1975 O OD2 . ASP   A 1 243 ? -40.08311  -12.66428 -105.74635 1.000 17.86252  ? 243 ASP   A OD2 1 
ATOM   1976 N N   . VAL   A 1 244 ? -44.83044  -10.64090 -106.62819 1.000 19.98843  ? 244 VAL   A N   1 
ATOM   1977 C CA  . VAL   A 1 244 ? -45.45025  -9.47389  -107.23351 1.000 15.77955  ? 244 VAL   A CA  1 
ATOM   1978 C C   . VAL   A 1 244 ? -44.95264  -8.24871  -106.47197 1.000 16.24945  ? 244 VAL   A C   1 
ATOM   1979 O O   . VAL   A 1 244 ? -45.48429  -7.90235  -105.41050 1.000 15.71548  ? 244 VAL   A O   1 
ATOM   1980 C CB  . VAL   A 1 244 ? -46.97061  -9.57343  -107.23493 1.000 14.45186  ? 244 VAL   A CB  1 
ATOM   1981 C CG1 . VAL   A 1 244 ? -47.56254  -8.29166  -107.78987 1.000 20.84802  ? 244 VAL   A CG1 1 
ATOM   1982 C CG2 . VAL   A 1 244 ? -47.40261  -10.78845 -108.06876 1.000 8.20718   ? 244 VAL   A CG2 1 
ATOM   1983 N N   . SER   A 1 245 ? -43.90579  -7.61358  -107.00082 1.000 19.16574  ? 245 SER   A N   1 
ATOM   1984 C CA  . SER   A 1 245 ? -43.27858  -6.47577  -106.35044 1.000 13.72061  ? 245 SER   A CA  1 
ATOM   1985 C C   . SER   A 1 245 ? -44.24735  -5.30477  -106.27137 1.000 21.85325  ? 245 SER   A C   1 
ATOM   1986 O O   . SER   A 1 245 ? -45.02902  -5.06137  -107.19353 1.000 18.06484  ? 245 SER   A O   1 
ATOM   1987 C CB  . SER   A 1 245 ? -42.02776  -6.07294  -107.12621 1.000 16.71400  ? 245 SER   A CB  1 
ATOM   1988 O OG  . SER   A 1 245 ? -41.49062  -4.84395  -106.66417 1.000 20.14077  ? 245 SER   A OG  1 
ATOM   1989 N N   . MET   A 1 246 ? -44.18939  -4.57679  -105.15391 1.000 21.59416  ? 246 MET   A N   1 
ATOM   1990 C CA  . MET   A 1 246 ? -44.92945  -3.32963  -105.00651 1.000 18.08376  ? 246 MET   A CA  1 
ATOM   1991 C C   . MET   A 1 246 ? -44.31316  -2.17646  -105.79866 1.000 19.82673  ? 246 MET   A C   1 
ATOM   1992 O O   . MET   A 1 246 ? -44.96504  -1.14247  -105.95378 1.000 27.02024  ? 246 MET   A O   1 
ATOM   1993 C CB  . MET   A 1 246 ? -45.00648  -2.93659  -103.52102 1.000 20.91043  ? 246 MET   A CB  1 
ATOM   1994 C CG  . MET   A 1 246 ? -45.91754  -3.79892  -102.65834 1.000 21.92166  ? 246 MET   A CG  1 
ATOM   1995 S SD  . MET   A 1 246 ? -47.54513  -3.93946  -103.40662 1.000 23.55535  ? 246 MET   A SD  1 
ATOM   1996 C CE  . MET   A 1 246 ? -48.51695  -4.67708  -102.07938 1.000 14.16345  ? 246 MET   A CE  1 
ATOM   1997 N N   . PHE   A 1 247 ? -43.07968  -2.30476  -106.28062 1.000 18.46131  ? 247 PHE   A N   1 
ATOM   1998 C CA  . PHE   A 1 247 ? -42.41660  -1.24058  -107.02169 1.000 19.60777  ? 247 PHE   A CA  1 
ATOM   1999 C C   . PHE   A 1 247 ? -42.14133  -1.69146  -108.44582 1.000 23.12972  ? 247 PHE   A C   1 
ATOM   2000 O O   . PHE   A 1 247 ? -41.60091  -2.78109  -108.65883 1.000 27.89783  ? 247 PHE   A O   1 
ATOM   2001 C CB  . PHE   A 1 247 ? -41.08010  -0.83876  -106.38668 1.000 23.39389  ? 247 PHE   A CB  1 
ATOM   2002 C CG  . PHE   A 1 247 ? -41.14622  -0.55994  -104.91285 1.000 22.96038  ? 247 PHE   A CG  1 
ATOM   2003 C CD1 . PHE   A 1 247 ? -41.58196  0.67050   -104.44329 1.000 24.72980  ? 247 PHE   A CD1 1 
ATOM   2004 C CD2 . PHE   A 1 247 ? -40.73060  -1.51270  -103.99863 1.000 21.22454  ? 247 PHE   A CD2 1 
ATOM   2005 C CE1 . PHE   A 1 247 ? -41.62162  0.94418   -103.07663 1.000 24.63866  ? 247 PHE   A CE1 1 
ATOM   2006 C CE2 . PHE   A 1 247 ? -40.77487  -1.25575  -102.62724 1.000 30.07725  ? 247 PHE   A CE2 1 
ATOM   2007 C CZ  . PHE   A 1 247 ? -41.21735  -0.02025  -102.16654 1.000 29.05780  ? 247 PHE   A CZ  1 
ATOM   2008 N N   . GLU   A 1 248 ? -42.46594  -0.83642  -109.41373 1.000 24.01689  ? 248 GLU   A N   1 
ATOM   2009 C CA  . GLU   A 1 248 ? -41.97893  -1.03837  -110.77087 1.000 19.12490  ? 248 GLU   A CA  1 
ATOM   2010 C C   . GLU   A 1 248 ? -40.45779  -0.90431  -110.80983 1.000 26.19580  ? 248 GLU   A C   1 
ATOM   2011 O O   . GLU   A 1 248 ? -39.81401  -0.41861  -109.87098 1.000 17.18626  ? 248 GLU   A O   1 
ATOM   2012 C CB  . GLU   A 1 248 ? -42.60818  -0.03468  -111.74066 1.000 19.15722  ? 248 GLU   A CB  1 
ATOM   2013 C CG  . GLU   A 1 248 ? -44.11974  -0.04246  -111.74890 1.000 16.52806  ? 248 GLU   A CG  1 
ATOM   2014 C CD  . GLU   A 1 248 ? -44.70098  -1.32970  -112.29179 1.000 21.50028  ? 248 GLU   A CD  1 
ATOM   2015 O OE1 . GLU   A 1 248 ? -44.11761  -1.91965  -113.23086 1.000 21.10656  ? 248 GLU   A OE1 1 
ATOM   2016 O OE2 . GLU   A 1 248 ? -45.74533  -1.76156  -111.76450 1.000 22.93393  ? 248 GLU   A OE2 1 
ATOM   2017 N N   . PHE   A 1 249 ? -39.88843  -1.32634  -111.93841 1.000 19.87733  ? 249 PHE   A N   1 
ATOM   2018 C CA  . PHE   A 1 249 ? -38.43942  -1.30512  -112.09472 1.000 24.90351  ? 249 PHE   A CA  1 
ATOM   2019 C C   . PHE   A 1 249 ? -37.86947  0.10193   -111.90924 1.000 32.01679  ? 249 PHE   A C   1 
ATOM   2020 O O   . PHE   A 1 249 ? -36.82462  0.27552   -111.27298 1.000 34.43401  ? 249 PHE   A O   1 
ATOM   2021 C CB  . PHE   A 1 249 ? -38.06502  -1.87203  -113.46517 1.000 36.01673  ? 249 PHE   A CB  1 
ATOM   2022 C CG  . PHE   A 1 249 ? -36.59609  -1.81313  -113.76349 1.000 48.75615  ? 249 PHE   A CG  1 
ATOM   2023 C CD1 . PHE   A 1 249 ? -35.72990  -2.76729  -113.23762 1.000 39.75013  ? 249 PHE   A CD1 1 
ATOM   2024 C CD2 . PHE   A 1 249 ? -36.07848  -0.80079  -114.57237 1.000 45.34058  ? 249 PHE   A CD2 1 
ATOM   2025 C CE1 . PHE   A 1 249 ? -34.37404  -2.71704  -113.51166 1.000 50.05248  ? 249 PHE   A CE1 1 
ATOM   2026 C CE2 . PHE   A 1 249 ? -34.72793  -0.73929  -114.85273 1.000 44.14728  ? 249 PHE   A CE2 1 
ATOM   2027 C CZ  . PHE   A 1 249 ? -33.86869  -1.69815  -114.32118 1.000 60.99216  ? 249 PHE   A CZ  1 
ATOM   2028 N N   . HIS   A 1 250 ? -38.54170  1.12099   -112.44705 1.000 34.91993  ? 250 HIS   A N   1 
ATOM   2029 C CA  . HIS   A 1 250 ? -38.05625  2.49455   -112.31617 1.000 30.41346  ? 250 HIS   A CA  1 
ATOM   2030 C C   . HIS   A 1 250 ? -38.24753  3.06149   -110.91587 1.000 32.99247  ? 250 HIS   A C   1 
ATOM   2031 O O   . HIS   A 1 250 ? -37.75417  4.15911   -110.64096 1.000 26.76303  ? 250 HIS   A O   1 
ATOM   2032 C CB  . HIS   A 1 250 ? -38.78720  3.40578   -113.30022 1.000 24.84283  ? 250 HIS   A CB  1 
ATOM   2033 C CG  . HIS   A 1 250 ? -40.26534  3.40401   -113.09391 1.000 30.88987  ? 250 HIS   A CG  1 
ATOM   2034 N ND1 . HIS   A 1 250 ? -40.87255  4.11030   -112.07537 1.000 32.83592  ? 250 HIS   A ND1 1 
ATOM   2035 C CD2 . HIS   A 1 250 ? -41.25126  2.71412   -113.71715 1.000 30.11517  ? 250 HIS   A CD2 1 
ATOM   2036 C CE1 . HIS   A 1 250 ? -42.17540  3.88419   -112.10314 1.000 31.74429  ? 250 HIS   A CE1 1 
ATOM   2037 N NE2 . HIS   A 1 250 ? -42.43110  3.04284   -113.09225 1.000 41.35915  ? 250 HIS   A NE2 1 
ATOM   2038 N N   . ASP   A 1 251 ? -38.97490  2.37395   -110.04445 1.000 24.67852  ? 251 ASP   A N   1 
ATOM   2039 C CA  . ASP   A 1 251 ? -39.38386  2.93311   -108.76049 1.000 22.51653  ? 251 ASP   A CA  1 
ATOM   2040 C C   . ASP   A 1 251 ? -38.35313  2.50303   -107.71898 1.000 28.71639  ? 251 ASP   A C   1 
ATOM   2041 O O   . ASP   A 1 251 ? -38.43009  1.40523   -107.16187 1.000 26.96807  ? 251 ASP   A O   1 
ATOM   2042 C CB  . ASP   A 1 251 ? -40.79885  2.47758   -108.41706 1.000 23.29240  ? 251 ASP   A CB  1 
ATOM   2043 C CG  . ASP   A 1 251 ? -41.35969  3.16609   -107.18857 1.000 26.34232  ? 251 ASP   A CG  1 
ATOM   2044 O OD1 . ASP   A 1 251 ? -40.57244  3.76704   -106.42719 1.000 22.55257  ? 251 ASP   A OD1 1 
ATOM   2045 O OD2 . ASP   A 1 251 ? -42.59271  3.09943   -106.97719 1.000 19.33774  ? 251 ASP   A OD2 1 
ATOM   2046 N N   . ARG   A 1 252 ? -37.39221  3.38231   -107.44358 1.000 26.47055  ? 252 ARG   A N   1 
ATOM   2047 C CA  . ARG   A 1 252 ? -36.28868  3.06109   -106.55572 1.000 26.41108  ? 252 ARG   A CA  1 
ATOM   2048 C C   . ARG   A 1 252 ? -36.45236  3.68012   -105.17185 1.000 30.56410  ? 252 ARG   A C   1 
ATOM   2049 O O   . ARG   A 1 252 ? -35.46509  3.83209   -104.44491 1.000 32.57020  ? 252 ARG   A O   1 
ATOM   2050 C CB  . ARG   A 1 252 ? -34.98098  3.48976   -107.20882 1.000 28.97325  ? 252 ARG   A CB  1 
ATOM   2051 C CG  . ARG   A 1 252 ? -34.71572  2.72905   -108.49505 1.000 26.45488  ? 252 ARG   A CG  1 
ATOM   2052 C CD  . ARG   A 1 252 ? -34.78467  1.23811   -108.18434 1.000 30.54355  ? 252 ARG   A CD  1 
ATOM   2053 N NE  . ARG   A 1 252 ? -34.84356  0.37067   -109.35726 1.000 33.91362  ? 252 ARG   A NE  1 
ATOM   2054 C CZ  . ARG   A 1 252 ? -33.78550  -0.21955  -109.90499 1.000 33.99560  ? 252 ARG   A CZ  1 
ATOM   2055 N NH1 . ARG   A 1 252 ? -32.57059  -0.02252  -109.40037 1.000 31.60898  ? 252 ARG   A NH1 1 
ATOM   2056 N NH2 . ARG   A 1 252 ? -33.94263  -0.99704  -110.96832 1.000 34.78690  ? 252 ARG   A NH2 1 
ATOM   2057 N N   . ARG   A 1 253 ? -37.68678  4.00551   -104.78893 1.000 23.01751  ? 253 ARG   A N   1 
ATOM   2058 C CA  . ARG   A 1 253 ? -37.96248  4.62775   -103.50421 1.000 19.18744  ? 253 ARG   A CA  1 
ATOM   2059 C C   . ARG   A 1 253 ? -37.50745  3.75278   -102.34400 1.000 39.31149  ? 253 ARG   A C   1 
ATOM   2060 O O   . ARG   A 1 253 ? -37.72100  2.53620   -102.33623 1.000 33.37157  ? 253 ARG   A O   1 
ATOM   2061 C CB  . ARG   A 1 253 ? -39.45082  4.90201   -103.37995 1.000 21.92684  ? 253 ARG   A CB  1 
ATOM   2062 C CG  . ARG   A 1 253 ? -39.93214  6.03888   -104.25686 1.000 22.31537  ? 253 ARG   A CG  1 
ATOM   2063 C CD  . ARG   A 1 253 ? -41.41174  6.25355   -104.02832 1.000 24.48783  ? 253 ARG   A CD  1 
ATOM   2064 N NE  . ARG   A 1 253 ? -42.20302  5.13445   -104.52704 1.000 24.70920  ? 253 ARG   A NE  1 
ATOM   2065 C CZ  . ARG   A 1 253 ? -43.49043  4.94660   -104.25689 1.000 25.60345  ? 253 ARG   A CZ  1 
ATOM   2066 N NH1 . ARG   A 1 253 ? -44.13508  5.81302   -103.48805 1.000 24.81761  ? 253 ARG   A NH1 1 
ATOM   2067 N NH2 . ARG   A 1 253 ? -44.13419  3.90203   -104.76831 1.000 20.99290  ? 253 ARG   A NH2 1 
ATOM   2068 N N   . THR   A 1 254 ? -36.90451  4.39052   -101.33708 1.000 34.63069  ? 254 THR   A N   1 
ATOM   2069 C CA  . THR   A 1 254 ? -36.40081  3.67818   -100.17343 1.000 36.24919  ? 254 THR   A CA  1 
ATOM   2070 C C   . THR   A 1 254 ? -37.15439  3.97193   -98.88014  1.000 38.84803  ? 254 THR   A C   1 
ATOM   2071 O O   . THR   A 1 254 ? -36.92125  3.27525   -97.88685  1.000 34.26937  ? 254 THR   A O   1 
ATOM   2072 C CB  . THR   A 1 254 ? -34.91981  4.00828   -99.95627  1.000 30.21629  ? 254 THR   A CB  1 
ATOM   2073 O OG1 . THR   A 1 254 ? -34.79392  5.38827   -99.58967  1.000 42.14943  ? 254 THR   A OG1 1 
ATOM   2074 C CG2 . THR   A 1 254 ? -34.12538  3.75274   -101.21699 1.000 38.22978  ? 254 THR   A CG2 1 
ATOM   2075 N N   . ASP   A 1 255 ? -38.06829  4.94636   -98.86371  1.000 33.58114  ? 255 ASP   A N   1 
ATOM   2076 C CA  A ASP   A 1 255 ? -38.63093  5.44148   -97.61193  0.541 36.66433  ? 255 ASP   A CA  1 
ATOM   2077 C CA  B ASP   A 1 255 ? -38.64264  5.46528   -97.62871  0.459 36.67508  ? 255 ASP   A CA  1 
ATOM   2078 C C   . ASP   A 1 255 ? -40.10363  5.07743   -97.43544  1.000 40.77706  ? 255 ASP   A C   1 
ATOM   2079 O O   . ASP   A 1 255 ? -40.80953  5.71394   -96.64929  1.000 47.96075  ? 255 ASP   A O   1 
ATOM   2080 C CB  A ASP   A 1 255 ? -38.43411  6.95734   -97.50869  0.541 37.75010  ? 255 ASP   A CB  1 
ATOM   2081 C CB  B ASP   A 1 255 ? -38.49884  6.98716   -97.57999  0.459 37.74946  ? 255 ASP   A CB  1 
ATOM   2082 C CG  A ASP   A 1 255 ? -36.95867  7.36548   -97.52331  0.541 39.32086  ? 255 ASP   A CG  1 
ATOM   2083 C CG  B ASP   A 1 255 ? -38.99440  7.66720   -98.84552  0.459 40.06311  ? 255 ASP   A CG  1 
ATOM   2084 O OD1 A ASP   A 1 255 ? -36.11157  6.63820   -96.95406  0.541 33.66302  ? 255 ASP   A OD1 1 
ATOM   2085 O OD1 B ASP   A 1 255 ? -39.29978  6.97102   -99.84343  0.459 34.55385  ? 255 ASP   A OD1 1 
ATOM   2086 O OD2 A ASP   A 1 255 ? -36.64756  8.42416   -98.10587  0.541 38.58772  ? 255 ASP   A OD2 1 
ATOM   2087 O OD2 B ASP   A 1 255 ? -39.08079  8.91315   -98.83009  0.459 40.52056  ? 255 ASP   A OD2 1 
ATOM   2088 N N   . LEU   A 1 256 ? -40.58113  4.05617   -98.12906  1.000 41.92434  ? 256 LEU   A N   1 
ATOM   2089 C CA  . LEU   A 1 256 ? -41.94625  3.58701   -97.92920  1.000 34.24285  ? 256 LEU   A CA  1 
ATOM   2090 C C   . LEU   A 1 256 ? -41.92695  2.58789   -96.78018  1.000 38.84666  ? 256 LEU   A C   1 
ATOM   2091 O O   . LEU   A 1 256 ? -41.39586  1.48376   -96.92218  1.000 39.85437  ? 256 LEU   A O   1 
ATOM   2092 C CB  . LEU   A 1 256 ? -42.49874  2.95589   -99.20476  1.000 33.63104  ? 256 LEU   A CB  1 
ATOM   2093 C CG  . LEU   A 1 256 ? -43.67975  3.64969   -99.88225  1.000 30.95688  ? 256 LEU   A CG  1 
ATOM   2094 C CD1 . LEU   A 1 256 ? -44.24658  2.76694   -100.97063 1.000 32.18727  ? 256 LEU   A CD1 1 
ATOM   2095 C CD2 . LEU   A 1 256 ? -44.76818  3.99149   -98.86844  1.000 38.33848  ? 256 LEU   A CD2 1 
ATOM   2096 N N   . ALA   A 1 257 ? -42.49495  2.97184   -95.63765  1.000 37.28833  ? 257 ALA   A N   1 
ATOM   2097 C CA  . ALA   A 1 257 ? -42.49748  2.08115   -94.48322  1.000 37.83194  ? 257 ALA   A CA  1 
ATOM   2098 C C   . ALA   A 1 257 ? -43.57897  1.01043   -94.55745  1.000 37.07664  ? 257 ALA   A C   1 
ATOM   2099 O O   . ALA   A 1 257 ? -43.49791  0.01205   -93.83059  1.000 35.72396  ? 257 ALA   A O   1 
ATOM   2100 C CB  . ALA   A 1 257 ? -42.67630  2.88824   -93.19522  1.000 42.12705  ? 257 ALA   A CB  1 
ATOM   2101 N N   . ALA   A 1 258 ? -44.59937  1.20839   -95.38757  1.000 27.19550  ? 258 ALA   A N   1 
ATOM   2102 C CA  . ALA   A 1 258 ? -45.69932  0.26253   -95.51473  1.000 29.68973  ? 258 ALA   A CA  1 
ATOM   2103 C C   . ALA   A 1 258 ? -46.30852  0.43807   -96.89316  1.000 31.74480  ? 258 ALA   A C   1 
ATOM   2104 O O   . ALA   A 1 258 ? -46.22509  1.53230   -97.46670  1.000 31.38577  ? 258 ALA   A O   1 
ATOM   2105 C CB  . ALA   A 1 258 ? -46.76341  0.48510   -94.42847  1.000 19.21642  ? 258 ALA   A CB  1 
ATOM   2106 N N   . PRO   A 1 259 ? -46.91383  -0.60492  -97.45443  1.000 31.21727  ? 259 PRO   A N   1 
ATOM   2107 C CA  . PRO   A 1 259 ? -47.58926  -0.44177  -98.74400  1.000 28.35643  ? 259 PRO   A CA  1 
ATOM   2108 C C   . PRO   A 1 259 ? -48.83450  0.41289   -98.58296  1.000 32.05128  ? 259 PRO   A C   1 
ATOM   2109 O O   . PRO   A 1 259 ? -49.53825  0.33435   -97.57017  1.000 31.27049  ? 259 PRO   A O   1 
ATOM   2110 C CB  . PRO   A 1 259 ? -47.94767  -1.87852  -99.13856  1.000 30.66685  ? 259 PRO   A CB  1 
ATOM   2111 C CG  . PRO   A 1 259 ? -48.11538  -2.58590  -97.82083  1.000 19.94465  ? 259 PRO   A CG  1 
ATOM   2112 C CD  . PRO   A 1 259 ? -47.11875  -1.95422  -96.88607  1.000 23.20286  ? 259 PRO   A CD  1 
ATOM   2113 N N   . THR   A 1 260 ? -49.10210  1.23843   -99.58875  1.000 31.68394  ? 260 THR   A N   1 
ATOM   2114 C CA  . THR   A 1 260 ? -50.35649  1.97316   -99.59466  1.000 27.70341  ? 260 THR   A CA  1 
ATOM   2115 C C   . THR   A 1 260 ? -51.51920  1.00320   -99.75752  1.000 28.69033  ? 260 THR   A C   1 
ATOM   2116 O O   . THR   A 1 260 ? -51.37498  -0.10271  -100.28964 1.000 31.76406  ? 260 THR   A O   1 
ATOM   2117 C CB  . THR   A 1 260 ? -50.38089  2.99856   -100.72370 1.000 28.72899  ? 260 THR   A CB  1 
ATOM   2118 O OG1 . THR   A 1 260 ? -50.82978  2.36322   -101.93647 1.000 32.97822  ? 260 THR   A OG1 1 
ATOM   2119 C CG2 . THR   A 1 260 ? -48.98599  3.57421   -100.93755 1.000 25.22098  ? 260 THR   A CG2 1 
ATOM   2120 N N   . SER   A 1 261 ? -52.69178  1.42759   -99.29885  1.000 21.25308  ? 261 SER   A N   1 
ATOM   2121 C CA  . SER   A 1 261 ? -53.85498  0.57793   -99.48522  1.000 26.48731  ? 261 SER   A CA  1 
ATOM   2122 C C   . SER   A 1 261 ? -54.15438  0.38216   -100.96207 1.000 26.35236  ? 261 SER   A C   1 
ATOM   2123 O O   . SER   A 1 261 ? -54.75965  -0.62621  -101.33727 1.000 30.09899  ? 261 SER   A O   1 
ATOM   2124 C CB  . SER   A 1 261 ? -55.06403  1.17038   -98.76986  1.000 28.47015  ? 261 SER   A CB  1 
ATOM   2125 O OG  . SER   A 1 261 ? -55.62385  2.19424   -99.56362  1.000 44.40940  ? 261 SER   A OG  1 
ATOM   2126 N N   . GLU   A 1 262 ? -53.75024  1.33706   -101.81152 1.000 28.96322  ? 262 GLU   A N   1 
ATOM   2127 C CA  . GLU   A 1 262 ? -53.90593  1.16400   -103.25492 1.000 30.70006  ? 262 GLU   A CA  1 
ATOM   2128 C C   . GLU   A 1 262 ? -52.96466  0.08795   -103.77543 1.000 30.51991  ? 262 GLU   A C   1 
ATOM   2129 O O   . GLU   A 1 262 ? -53.35600  -0.72609  -104.62187 1.000 26.47455  ? 262 GLU   A O   1 
ATOM   2130 C CB  . GLU   A 1 262 ? -53.64554  2.47461   -103.99824 1.000 31.51967  ? 262 GLU   A CB  1 
ATOM   2131 C CG  . GLU   A 1 262 ? -54.69510  3.55161   -103.79979 1.000 63.58931  ? 262 GLU   A CG  1 
ATOM   2132 C CD  . GLU   A 1 262 ? -54.66686  4.15983   -102.39888 1.000 70.84731  ? 262 GLU   A CD  1 
ATOM   2133 O OE1 . GLU   A 1 262 ? -55.76550  4.32589   -101.81040 1.000 61.37365  ? 262 GLU   A OE1 1 
ATOM   2134 O OE2 . GLU   A 1 262 ? -53.55040  4.45880   -101.89287 1.000 49.46477  ? 262 GLU   A OE2 1 
ATOM   2135 N N   . MET   A 1 263 ? -51.71541  0.08385   -103.29116 1.000 21.47829  ? 263 MET   A N   1 
ATOM   2136 C CA  . MET   A 1 263 ? -50.78815  -0.99741  -103.61499 1.000 24.47359  ? 263 MET   A CA  1 
ATOM   2137 C C   . MET   A 1 263 ? -51.36756  -2.35062  -103.21662 1.000 24.24779  ? 263 MET   A C   1 
ATOM   2138 O O   . MET   A 1 263 ? -51.35499  -3.30359  -104.00614 1.000 23.51251  ? 263 MET   A O   1 
ATOM   2139 C CB  . MET   A 1 263 ? -49.44851  -0.76842  -102.91153 1.000 24.67630  ? 263 MET   A CB  1 
ATOM   2140 C CG  . MET   A 1 263 ? -48.56311  0.30738   -103.54122 1.000 25.44931  ? 263 MET   A CG  1 
ATOM   2141 S SD  . MET   A 1 263 ? -46.98184  0.39102   -102.67292 1.000 30.72098  ? 263 MET   A SD  1 
ATOM   2142 C CE  . MET   A 1 263 ? -45.90589  1.04310   -103.95124 1.000 33.82749  ? 263 MET   A CE  1 
ATOM   2143 N N   . ILE   A 1 264 ? -51.88003  -2.44974  -101.98614 1.000 18.52762  ? 264 ILE   A N   1 
ATOM   2144 C CA  . ILE   A 1 264 ? -52.39261  -3.72088  -101.48519 1.000 16.85838  ? 264 ILE   A CA  1 
ATOM   2145 C C   . ILE   A 1 264 ? -53.57499  -4.17746  -102.32423 1.000 18.58427  ? 264 ILE   A C   1 
ATOM   2146 O O   . ILE   A 1 264 ? -53.71933  -5.36881  -102.63722 1.000 27.36949  ? 264 ILE   A O   1 
ATOM   2147 C CB  . ILE   A 1 264 ? -52.76849  -3.58381  -99.99579  1.000 15.76763  ? 264 ILE   A CB  1 
ATOM   2148 C CG1 . ILE   A 1 264 ? -51.51887  -3.58586  -99.12477  1.000 28.30287  ? 264 ILE   A CG1 1 
ATOM   2149 C CG2 . ILE   A 1 264 ? -53.71610  -4.68922  -99.55914  1.000 11.54516  ? 264 ILE   A CG2 1 
ATOM   2150 C CD1 . ILE   A 1 264 ? -50.88721  -4.98276  -98.98233  1.000 30.68687  ? 264 ILE   A CD1 1 
ATOM   2151 N N   . GLU   A 1 265 ? -54.43653  -3.23578  -102.70846 1.000 20.16132  ? 265 GLU   A N   1 
ATOM   2152 C CA  . GLU   A 1 265 ? -55.64163  -3.57707  -103.46275 1.000 23.65202  ? 265 GLU   A CA  1 
ATOM   2153 C C   . GLU   A 1 265 ? -55.29048  -4.00783  -104.88043 1.000 22.98000  ? 265 GLU   A C   1 
ATOM   2154 O O   . GLU   A 1 265 ? -55.80811  -5.01391  -105.38627 1.000 21.06594  ? 265 GLU   A O   1 
ATOM   2155 C CB  . GLU   A 1 265 ? -56.58943  -2.37661  -103.47918 1.000 18.17354  ? 265 GLU   A CB  1 
ATOM   2156 C CG  . GLU   A 1 265 ? -57.91662  -2.63569  -104.14905 1.000 27.09620  ? 265 GLU   A CG  1 
ATOM   2157 C CD  . GLU   A 1 265 ? -58.82113  -1.41339  -104.11688 1.000 39.74085  ? 265 GLU   A CD  1 
ATOM   2158 O OE1 . GLU   A 1 265 ? -58.41778  -0.34168  -104.62666 1.000 53.96814  ? 265 GLU   A OE1 1 
ATOM   2159 O OE2 . GLU   A 1 265 ? -59.93451  -1.51947  -103.56967 1.000 41.54631  ? 265 GLU   A OE2 1 
ATOM   2160 N N   . ARG   A 1 266 ? -54.40337  -3.25435  -105.53719 1.000 16.90737  ? 266 ARG   A N   1 
ATOM   2161 C CA  . ARG   A 1 266 ? -54.01826  -3.61158  -106.89356 1.000 26.31705  ? 266 ARG   A CA  1 
ATOM   2162 C C   . ARG   A 1 266 ? -53.27360  -4.94425  -106.91114 1.000 25.69274  ? 266 ARG   A C   1 
ATOM   2163 O O   . ARG   A 1 266 ? -53.46098  -5.75221  -107.83046 1.000 21.44196  ? 266 ARG   A O   1 
ATOM   2164 C CB  . ARG   A 1 266 ? -53.18639  -2.48468  -107.50521 1.000 20.31173  ? 266 ARG   A CB  1 
ATOM   2165 C CG  . ARG   A 1 266 ? -52.55541  -2.80308  -108.85283 1.000 27.74249  ? 266 ARG   A CG  1 
ATOM   2166 C CD  . ARG   A 1 266 ? -53.54786  -3.30649  -109.91933 1.000 29.26007  ? 266 ARG   A CD  1 
ATOM   2167 N NE  . ARG   A 1 266 ? -52.81952  -3.69005  -111.12907 1.000 27.12659  ? 266 ARG   A NE  1 
ATOM   2168 C CZ  . ARG   A 1 266 ? -53.21377  -4.60889  -112.01216 1.000 34.22311  ? 266 ARG   A CZ  1 
ATOM   2169 N NH1 . ARG   A 1 266 ? -54.35545  -5.27574  -111.84084 1.000 28.03983  ? 266 ARG   A NH1 1 
ATOM   2170 N NH2 . ARG   A 1 266 ? -52.44968  -4.87125  -113.07364 1.000 24.96333  ? 266 ARG   A NH2 1 
ATOM   2171 N N   . GLN   A 1 267 ? -52.46668  -5.21148  -105.87508 1.000 18.59760  ? 267 GLN   A N   1 
ATOM   2172 C CA  . GLN   A 1 267 ? -51.77354  -6.49519  -105.78197 1.000 20.38448  ? 267 GLN   A CA  1 
ATOM   2173 C C   . GLN   A 1 267 ? -52.75461  -7.65202  -105.65011 1.000 21.01310  ? 267 GLN   A C   1 
ATOM   2174 O O   . GLN   A 1 267 ? -52.57865  -8.70025  -106.28944 1.000 22.76041  ? 267 GLN   A O   1 
ATOM   2175 C CB  . GLN   A 1 267 ? -50.79397  -6.49794  -104.60292 1.000 19.72797  ? 267 GLN   A CB  1 
ATOM   2176 C CG  . GLN   A 1 267 ? -50.02421  -7.81609  -104.47957 1.000 15.01197  ? 267 GLN   A CG  1 
ATOM   2177 C CD  . GLN   A 1 267 ? -49.11985  -7.85865  -103.26395 1.000 27.57305  ? 267 GLN   A CD  1 
ATOM   2178 O OE1 . GLN   A 1 267 ? -49.60082  -7.94793  -102.13041 1.000 19.18415  ? 267 GLN   A OE1 1 
ATOM   2179 N NE2 . GLN   A 1 267 ? -47.79450  -7.79576  -103.49186 1.000 20.18120  ? 267 GLN   A NE2 1 
ATOM   2180 N N   . ALA   A 1 268 ? -53.78728  -7.48875  -104.81898 1.000 16.28060  ? 268 ALA   A N   1 
ATOM   2181 C CA  . ALA   A 1 268 ? -54.82966  -8.50655  -104.73895 1.000 18.60707  ? 268 ALA   A CA  1 
ATOM   2182 C C   . ALA   A 1 268 ? -55.45232  -8.75743  -106.10663 1.000 18.83960  ? 268 ALA   A C   1 
ATOM   2183 O O   . ALA   A 1 268 ? -55.64104  -9.91099  -106.51189 1.000 20.74601  ? 268 ALA   A O   1 
ATOM   2184 C CB  . ALA   A 1 268 ? -55.90068  -8.09853  -103.71406 1.000 18.51441  ? 268 ALA   A CB  1 
ATOM   2185 N N   . GLU   A 1 269 ? -55.79241  -7.68509  -106.83248 1.000 23.63410  ? 269 GLU   A N   1 
ATOM   2186 C CA  . GLU   A 1 269 ? -56.35556  -7.85677  -108.16989 1.000 22.88161  ? 269 GLU   A CA  1 
ATOM   2187 C C   . GLU   A 1 269 ? -55.35875  -8.54885  -109.09364 1.000 20.10903  ? 269 GLU   A C   1 
ATOM   2188 O O   . GLU   A 1 269 ? -55.70148  -9.50100  -109.80967 1.000 15.86161  ? 269 GLU   A O   1 
ATOM   2189 C CB  . GLU   A 1 269 ? -56.76056  -6.50439  -108.74575 1.000 22.23436  ? 269 GLU   A CB  1 
ATOM   2190 C CG  . GLU   A 1 269 ? -57.33790  -6.62683  -110.14807 1.000 30.17628  ? 269 GLU   A CG  1 
ATOM   2191 C CD  . GLU   A 1 269 ? -57.74969  -5.30046  -110.74634 1.000 30.90317  ? 269 GLU   A CD  1 
ATOM   2192 O OE1 . GLU   A 1 269 ? -56.89334  -4.38936  -110.86065 1.000 26.13539  ? 269 GLU   A OE1 1 
ATOM   2193 O OE2 . GLU   A 1 269 ? -58.93908  -5.17889  -111.09625 1.000 46.04320  ? 269 GLU   A OE2 1 
ATOM   2194 N N   . ARG   A 1 270 ? -54.10673  -8.08738  -109.06930 1.000 19.56626  ? 270 ARG   A N   1 
ATOM   2195 C CA  . ARG   A 1 270 ? -53.08027  -8.65660  -109.93043 1.000 18.63351  ? 270 ARG   A CA  1 
ATOM   2196 C C   . ARG   A 1 270 ? -52.89095  -10.14706 -109.65611 1.000 20.36059  ? 270 ARG   A C   1 
ATOM   2197 O O   . ARG   A 1 270 ? -52.80301  -10.95286 -110.59157 1.000 16.68287  ? 270 ARG   A O   1 
ATOM   2198 C CB  . ARG   A 1 270 ? -51.78668  -7.87851  -109.73320 1.000 20.13023  ? 270 ARG   A CB  1 
ATOM   2199 C CG  . ARG   A 1 270 ? -50.60561  -8.44259  -110.44600 1.000 24.56267  ? 270 ARG   A CG  1 
ATOM   2200 C CD  . ARG   A 1 270 ? -50.58535  -8.04318  -111.89976 1.000 23.53574  ? 270 ARG   A CD  1 
ATOM   2201 N NE  . ARG   A 1 270 ? -49.21350  -8.09990  -112.38395 1.000 20.19143  ? 270 ARG   A NE  1 
ATOM   2202 C CZ  . ARG   A 1 270 ? -48.87006  -8.25281  -113.65492 1.000 21.03769  ? 270 ARG   A CZ  1 
ATOM   2203 N NH1 . ARG   A 1 270 ? -49.80147  -8.37071  -114.58255 1.000 17.33844  ? 270 ARG   A NH1 1 
ATOM   2204 N NH2 . ARG   A 1 270 ? -47.58792  -8.29078  -113.99530 1.000 23.41929  ? 270 ARG   A NH2 1 
ATOM   2205 N N   . TYR   A 1 271 ? -52.88119  -10.54027 -108.37886 1.000 15.18256  ? 271 TYR   A N   1 
ATOM   2206 C CA  . TYR   A 1 271 ? -52.72125  -11.95366 -108.05166 1.000 15.41774  ? 271 TYR   A CA  1 
ATOM   2207 C C   . TYR   A 1 271 ? -53.94342  -12.76289 -108.46479 1.000 18.83098  ? 271 TYR   A C   1 
ATOM   2208 O O   . TYR   A 1 271 ? -53.81660  -13.91277 -108.91452 1.000 18.40597  ? 271 TYR   A O   1 
ATOM   2209 C CB  . TYR   A 1 271 ? -52.45842  -12.12315 -106.55448 1.000 11.85336  ? 271 TYR   A CB  1 
ATOM   2210 C CG  . TYR   A 1 271 ? -50.99488  -12.31249 -106.17197 1.000 14.54417  ? 271 TYR   A CG  1 
ATOM   2211 C CD1 . TYR   A 1 271 ? -50.28021  -13.43347 -106.58002 1.000 13.67913  ? 271 TYR   A CD1 1 
ATOM   2212 C CD2 . TYR   A 1 271 ? -50.34351  -11.38238 -105.36089 1.000 14.79792  ? 271 TYR   A CD2 1 
ATOM   2213 C CE1 . TYR   A 1 271 ? -48.94124  -13.61695 -106.19431 1.000 17.63915  ? 271 TYR   A CE1 1 
ATOM   2214 C CE2 . TYR   A 1 271 ? -49.02484  -11.55312 -104.97800 1.000 14.48703  ? 271 TYR   A CE2 1 
ATOM   2215 C CZ  . TYR   A 1 271 ? -48.32693  -12.67067 -105.39468 1.000 14.04770  ? 271 TYR   A CZ  1 
ATOM   2216 O OH  . TYR   A 1 271 ? -47.01844  -12.81834 -105.00944 1.000 20.48108  ? 271 TYR   A OH  1 
ATOM   2217 N N   . GLY   A 1 272 ? -55.13960  -12.19919 -108.28153 1.000 17.01694  ? 272 GLY   A N   1 
ATOM   2218 C CA  . GLY   A 1 272 ? -56.33112  -12.87568 -108.76007 1.000 18.55647  ? 272 GLY   A CA  1 
ATOM   2219 C C   . GLY   A 1 272 ? -56.29063  -13.11600 -110.25894 1.000 21.81132  ? 272 GLY   A C   1 
ATOM   2220 O O   . GLY   A 1 272 ? -56.57811  -14.22114 -110.73078 1.000 17.08694  ? 272 GLY   A O   1 
ATOM   2221 N N   . GLN   A 1 273 ? -55.91588  -12.08566 -111.02797 1.000 14.03906  ? 273 GLN   A N   1 
ATOM   2222 C CA  . GLN   A 1 273 ? -55.88636  -12.23394 -112.48078 1.000 20.25239  ? 273 GLN   A CA  1 
ATOM   2223 C C   . GLN   A 1 273 ? -54.86687  -13.28490 -112.89500 1.000 21.78195  ? 273 GLN   A C   1 
ATOM   2224 O O   . GLN   A 1 273 ? -55.14021  -14.13812 -113.74843 1.000 22.72490  ? 273 GLN   A O   1 
ATOM   2225 C CB  . GLN   A 1 273 ? -55.56082  -10.89225 -113.14479 1.000 18.37353  ? 273 GLN   A CB  1 
ATOM   2226 C CG  . GLN   A 1 273 ? -56.59757  -9.78812  -112.93953 1.000 14.77332  ? 273 GLN   A CG  1 
ATOM   2227 C CD  . GLN   A 1 273 ? -56.05229  -8.39794  -113.28844 1.000 29.11957  ? 273 GLN   A CD  1 
ATOM   2228 O OE1 . GLN   A 1 273 ? -54.85833  -8.10756  -113.11656 1.000 29.07393  ? 273 GLN   A OE1 1 
ATOM   2229 N NE2 . GLN   A 1 273 ? -56.92548  -7.53598  -113.77636 1.000 26.31715  ? 273 GLN   A NE2 1 
ATOM   2230 N N   . ILE   A 1 274 ? -53.69532  -13.24912 -112.26576 1.000 21.50990  ? 274 ILE   A N   1 
ATOM   2231 C CA  . ILE   A 1 274 ? -52.59276  -14.13273 -112.62202 1.000 18.94711  ? 274 ILE   A CA  1 
ATOM   2232 C C   . ILE   A 1 274 ? -52.97080  -15.59444 -112.40116 1.000 20.89695  ? 274 ILE   A C   1 
ATOM   2233 O O   . ILE   A 1 274 ? -52.73879  -16.45147 -113.26617 1.000 18.28311  ? 274 ILE   A O   1 
ATOM   2234 C CB  . ILE   A 1 274 ? -51.35318  -13.73390 -111.80996 1.000 18.79502  ? 274 ILE   A CB  1 
ATOM   2235 C CG1 . ILE   A 1 274 ? -50.73510  -12.47901 -112.41239 1.000 24.62431  ? 274 ILE   A CG1 1 
ATOM   2236 C CG2 . ILE   A 1 274 ? -50.36092  -14.85617 -111.73606 1.000 23.65559  ? 274 ILE   A CG2 1 
ATOM   2237 C CD1 . ILE   A 1 274 ? -49.79877  -11.79788 -111.44532 1.000 28.04690  ? 274 ILE   A CD1 1 
ATOM   2238 N N   . PHE   A 1 275 ? -53.55360  -15.90263 -111.23528 1.000 17.90866  ? 275 PHE   A N   1 
ATOM   2239 C CA  . PHE   A 1 275 ? -53.94105  -17.28071 -110.94423 1.000 20.51031  ? 275 PHE   A CA  1 
ATOM   2240 C C   . PHE   A 1 275 ? -55.16445  -17.70585 -111.74957 1.000 21.81306  ? 275 PHE   A C   1 
ATOM   2241 O O   . PHE   A 1 275 ? -55.32599  -18.89520 -112.05205 1.000 20.06599  ? 275 PHE   A O   1 
ATOM   2242 C CB  . PHE   A 1 275 ? -54.17880  -17.46045 -109.43759 1.000 17.91278  ? 275 PHE   A CB  1 
ATOM   2243 C CG  . PHE   A 1 275 ? -52.92074  -17.77860 -108.68013 1.000 20.89398  ? 275 PHE   A CG  1 
ATOM   2244 C CD1 . PHE   A 1 275 ? -52.46416  -19.07962 -108.58829 1.000 21.20418  ? 275 PHE   A CD1 1 
ATOM   2245 C CD2 . PHE   A 1 275 ? -52.15365  -16.76523 -108.12329 1.000 18.12604  ? 275 PHE   A CD2 1 
ATOM   2246 C CE1 . PHE   A 1 275 ? -51.28325  -19.37029 -107.92634 1.000 13.89660  ? 275 PHE   A CE1 1 
ATOM   2247 C CE2 . PHE   A 1 275 ? -50.99311  -17.04955 -107.45487 1.000 19.02968  ? 275 PHE   A CE2 1 
ATOM   2248 C CZ  . PHE   A 1 275 ? -50.55361  -18.35876 -107.35974 1.000 20.95691  ? 275 PHE   A CZ  1 
ATOM   2249 N N   . ALA   A 1 276 ? -56.03024  -16.76312 -112.11556 1.000 19.99993  ? 276 ALA   A N   1 
ATOM   2250 C CA  . ALA   A 1 276 ? -57.06556  -17.09133 -113.08488 1.000 21.83280  ? 276 ALA   A CA  1 
ATOM   2251 C C   . ALA   A 1 276 ? -56.42533  -17.55464 -114.38196 1.000 19.48752  ? 276 ALA   A C   1 
ATOM   2252 O O   . ALA   A 1 276 ? -56.76891  -18.61184 -114.92212 1.000 21.99499  ? 276 ALA   A O   1 
ATOM   2253 C CB  . ALA   A 1 276 ? -57.97275  -15.88157 -113.32404 1.000 19.04516  ? 276 ALA   A CB  1 
ATOM   2254 N N   . LEU   A 1 277 ? -55.44782  -16.79048 -114.86893 1.000 19.27817  ? 277 LEU   A N   1 
ATOM   2255 C CA  . LEU   A 1 277 ? -54.73748  -17.17625 -116.08180 1.000 20.26785  ? 277 LEU   A CA  1 
ATOM   2256 C C   . LEU   A 1 277 ? -54.02354  -18.52418 -115.92109 1.000 24.22388  ? 277 LEU   A C   1 
ATOM   2257 O O   . LEU   A 1 277 ? -54.10257  -19.37971 -116.81428 1.000 21.39689  ? 277 LEU   A O   1 
ATOM   2258 C CB  . LEU   A 1 277 ? -53.76628  -16.07221 -116.47238 1.000 15.84905  ? 277 LEU   A CB  1 
ATOM   2259 C CG  . LEU   A 1 277 ? -53.28298  -16.11857 -117.92066 1.000 25.05844  ? 277 LEU   A CG  1 
ATOM   2260 C CD1 . LEU   A 1 277 ? -54.45289  -16.26404 -118.87480 1.000 27.23889  ? 277 LEU   A CD1 1 
ATOM   2261 C CD2 . LEU   A 1 277 ? -52.45272  -14.87415 -118.26824 1.000 25.57113  ? 277 LEU   A CD2 1 
ATOM   2262 N N   . PHE   A 1 278 ? -53.35197  -18.75099 -114.78218 1.000 20.07060  ? 278 PHE   A N   1 
ATOM   2263 C CA  . PHE   A 1 278 ? -52.68989  -20.04101 -114.56228 1.000 20.79324  ? 278 PHE   A CA  1 
ATOM   2264 C C   . PHE   A 1 278 ? -53.69470  -21.19569 -114.59428 1.000 21.01711  ? 278 PHE   A C   1 
ATOM   2265 O O   . PHE   A 1 278 ? -53.45795  -22.22059 -115.24301 1.000 19.73610  ? 278 PHE   A O   1 
ATOM   2266 C CB  . PHE   A 1 278 ? -51.92996  -20.05483 -113.22781 1.000 17.05135  ? 278 PHE   A CB  1 
ATOM   2267 C CG  . PHE   A 1 278 ? -50.73152  -19.14029 -113.17523 1.000 17.19520  ? 278 PHE   A CG  1 
ATOM   2268 C CD1 . PHE   A 1 278 ? -50.16033  -18.63063 -114.33378 1.000 17.46523  ? 278 PHE   A CD1 1 
ATOM   2269 C CD2 . PHE   A 1 278 ? -50.17795  -18.78507 -111.95007 1.000 17.12474  ? 278 PHE   A CD2 1 
ATOM   2270 C CE1 . PHE   A 1 278 ? -49.05694  -17.77629 -114.27058 1.000 17.63367  ? 278 PHE   A CE1 1 
ATOM   2271 C CE2 . PHE   A 1 278 ? -49.07288  -17.93512 -111.87888 1.000 21.29135  ? 278 PHE   A CE2 1 
ATOM   2272 C CZ  . PHE   A 1 278 ? -48.51229  -17.43125 -113.04288 1.000 20.22458  ? 278 PHE   A CZ  1 
ATOM   2273 N N   . LYS   A 1 279 ? -54.80773  -21.06144 -113.86518 1.000 21.13242  ? 279 LYS   A N   1 
ATOM   2274 C CA  . LYS   A 1 279 ? -55.81888  -22.11548 -113.85253 1.000 24.80046  ? 279 LYS   A CA  1 
ATOM   2275 C C   . LYS   A 1 279 ? -56.32253  -22.40375 -115.26384 1.000 24.89376  ? 279 LYS   A C   1 
ATOM   2276 O O   . LYS   A 1 279 ? -56.50316  -23.56409 -115.64528 1.000 23.81659  ? 279 LYS   A O   1 
ATOM   2277 C CB  . LYS   A 1 279 ? -56.96995  -21.71506 -112.92984 1.000 24.36558  ? 279 LYS   A CB  1 
ATOM   2278 C CG  . LYS   A 1 279 ? -57.91156  -22.84769 -112.50196 1.000 38.34945  ? 279 LYS   A CG  1 
ATOM   2279 C CD  . LYS   A 1 279 ? -59.00271  -22.32202 -111.54536 1.000 29.53321  ? 279 LYS   A CD  1 
ATOM   2280 C CE  . LYS   A 1 279 ? -59.88174  -23.43646 -110.95130 1.000 40.88259  ? 279 LYS   A CE  1 
ATOM   2281 N NZ  . LYS   A 1 279 ? -59.28376  -24.11552 -109.74003 1.000 36.99824  ? 279 LYS   A NZ  1 
ATOM   2282 N N   . GLU   A 1 280 ? -56.52061  -21.35627 -116.06271 1.000 22.01942  ? 280 GLU   A N   1 
ATOM   2283 C CA  . GLU   A 1 280 ? -56.91905  -21.54010 -117.45302 1.000 21.28064  ? 280 GLU   A CA  1 
ATOM   2284 C C   . GLU   A 1 280 ? -55.91665  -22.40485 -118.21425 1.000 23.28757  ? 280 GLU   A C   1 
ATOM   2285 O O   . GLU   A 1 280 ? -56.30966  -23.22219 -119.05052 1.000 26.15755  ? 280 GLU   A O   1 
ATOM   2286 C CB  . GLU   A 1 280 ? -57.08001  -20.17149 -118.11850 1.000 26.73149  ? 280 GLU   A CB  1 
ATOM   2287 C CG  . GLU   A 1 280 ? -57.61862  -20.21237 -119.52451 1.000 24.05263  ? 280 GLU   A CG  1 
ATOM   2288 C CD  . GLU   A 1 280 ? -57.90061  -18.82583 -120.09022 1.000 31.46549  ? 280 GLU   A CD  1 
ATOM   2289 O OE1 . GLU   A 1 280 ? -57.95103  -17.83700 -119.31778 1.000 26.58520  ? 280 GLU   A OE1 1 
ATOM   2290 O OE2 . GLU   A 1 280 ? -58.07568  -18.72938 -121.32376 1.000 40.12789  ? 280 GLU   A OE2 1 
ATOM   2291 N N   . TYR   A 1 281 ? -54.61758  -22.26289 -117.92850 1.000 21.84385  ? 281 TYR   A N   1 
ATOM   2292 C CA  . TYR   A 1 281 ? -53.60068  -23.07359 -118.58936 1.000 24.27404  ? 281 TYR   A CA  1 
ATOM   2293 C C   . TYR   A 1 281 ? -53.12693  -24.23658 -117.72357 1.000 27.89898  ? 281 TYR   A C   1 
ATOM   2294 O O   . TYR   A 1 281 ? -51.97477  -24.68462 -117.85418 1.000 24.13020  ? 281 TYR   A O   1 
ATOM   2295 C CB  . TYR   A 1 281 ? -52.43377  -22.19711 -119.04309 1.000 23.15778  ? 281 TYR   A CB  1 
ATOM   2296 C CG  . TYR   A 1 281 ? -52.86038  -21.37227 -120.22312 1.000 21.47981  ? 281 TYR   A CG  1 
ATOM   2297 C CD1 . TYR   A 1 281 ? -52.81815  -21.89824 -121.51333 1.000 22.58647  ? 281 TYR   A CD1 1 
ATOM   2298 C CD2 . TYR   A 1 281 ? -53.38414  -20.09399 -120.04602 1.000 21.79815  ? 281 TYR   A CD2 1 
ATOM   2299 C CE1 . TYR   A 1 281 ? -53.25372  -21.15031 -122.61356 1.000 20.12951  ? 281 TYR   A CE1 1 
ATOM   2300 C CE2 . TYR   A 1 281 ? -53.83158  -19.34068 -121.12976 1.000 20.30739  ? 281 TYR   A CE2 1 
ATOM   2301 C CZ  . TYR   A 1 281 ? -53.76338  -19.87372 -122.41096 1.000 25.76911  ? 281 TYR   A CZ  1 
ATOM   2302 O OH  . TYR   A 1 281 ? -54.20074  -19.12765 -123.48540 1.000 25.60016  ? 281 TYR   A OH  1 
ATOM   2303 N N   . ARG   A 1 282 ? -54.02799  -24.76952 -116.88366 1.000 22.71330  ? 282 ARG   A N   1 
ATOM   2304 C CA  . ARG   A 1 282 ? -53.69127  -25.88454 -116.00197 1.000 26.15037  ? 282 ARG   A CA  1 
ATOM   2305 C C   . ARG   A 1 282 ? -53.13460  -27.08371 -116.76536 1.000 30.50195  ? 282 ARG   A C   1 
ATOM   2306 O O   . ARG   A 1 282 ? -52.35821  -27.86490 -116.20312 1.000 22.72359  ? 282 ARG   A O   1 
ATOM   2307 C CB  . ARG   A 1 282 ? -54.92278  -26.30184 -115.20273 1.000 31.08974  ? 282 ARG   A CB  1 
ATOM   2308 C CG  . ARG   A 1 282 ? -56.15223  -26.61516 -116.06239 1.000 28.33799  ? 282 ARG   A CG  1 
ATOM   2309 C CD  . ARG   A 1 282 ? -57.38167  -26.84388 -115.18338 1.000 25.40245  ? 282 ARG   A CD  1 
ATOM   2310 N NE  . ARG   A 1 282 ? -57.23009  -28.04413 -114.36782 1.000 28.06585  ? 282 ARG   A NE  1 
ATOM   2311 C CZ  . ARG   A 1 282 ? -57.53060  -29.27000 -114.79268 1.000 33.90417  ? 282 ARG   A CZ  1 
ATOM   2312 N NH1 . ARG   A 1 282 ? -58.00282  -29.45057 -116.01804 1.000 33.21144  ? 282 ARG   A NH1 1 
ATOM   2313 N NH2 . ARG   A 1 282 ? -57.34814  -30.31889 -114.00318 1.000 30.96362  ? 282 ARG   A NH2 1 
ATOM   2314 N N   . ASP   A 1 283 ? -53.51175  -27.24913 -118.03890 1.000 25.34380  ? 283 ASP   A N   1 
ATOM   2315 C CA  . ASP   A 1 283 ? -53.04190  -28.40059 -118.79988 1.000 24.68415  ? 283 ASP   A CA  1 
ATOM   2316 C C   . ASP   A 1 283 ? -51.55013  -28.33370 -119.11321 1.000 25.17798  ? 283 ASP   A C   1 
ATOM   2317 O O   . ASP   A 1 283 ? -50.94146  -29.38245 -119.33291 1.000 28.56781  ? 283 ASP   A O   1 
ATOM   2318 C CB  . ASP   A 1 283 ? -53.85356  -28.55025 -120.09466 1.000 27.57038  ? 283 ASP   A CB  1 
ATOM   2319 C CG  . ASP   A 1 283 ? -55.31540  -28.94044 -119.83275 1.000 38.65160  ? 283 ASP   A CG  1 
ATOM   2320 O OD1 . ASP   A 1 283 ? -55.56030  -29.70690 -118.87444 1.000 31.37393  ? 283 ASP   A OD1 1 
ATOM   2321 O OD2 . ASP   A 1 283 ? -56.22134  -28.46945 -120.56907 1.000 39.22717  ? 283 ASP   A OD2 1 
ATOM   2322 N N   . VAL   A 1 284 ? -50.93910  -27.14980 -119.12490 1.000 20.33365  ? 284 VAL   A N   1 
ATOM   2323 C CA  . VAL   A 1 284 ? -49.50830  -27.04328 -119.39343 1.000 19.82128  ? 284 VAL   A CA  1 
ATOM   2324 C C   . VAL   A 1 284 ? -48.70866  -26.53446 -118.19803 1.000 26.64295  ? 284 VAL   A C   1 
ATOM   2325 O O   . VAL   A 1 284 ? -47.48179  -26.72572 -118.15369 1.000 31.49532  ? 284 VAL   A O   1 
ATOM   2326 C CB  . VAL   A 1 284 ? -49.23332  -26.16824 -120.63460 1.000 24.38078  ? 284 VAL   A CB  1 
ATOM   2327 C CG1 . VAL   A 1 284 ? -49.68211  -26.90087 -121.90563 1.000 29.61287  ? 284 VAL   A CG1 1 
ATOM   2328 C CG2 . VAL   A 1 284 ? -49.96007  -24.83568 -120.53179 1.000 20.13143  ? 284 VAL   A CG2 1 
ATOM   2329 N N   . ILE   A 1 285 ? -49.33355  -25.92328 -117.20781 1.000 28.19872  ? 285 ILE   A N   1 
ATOM   2330 C CA  . ILE   A 1 285 ? -48.62976  -25.50765 -116.00589 1.000 23.78164  ? 285 ILE   A CA  1 
ATOM   2331 C C   . ILE   A 1 285 ? -48.79477  -26.60721 -114.96581 1.000 22.13409  ? 285 ILE   A C   1 
ATOM   2332 O O   . ILE   A 1 285 ? -49.91715  -26.96905 -114.59234 1.000 24.53606  ? 285 ILE   A O   1 
ATOM   2333 C CB  . ILE   A 1 285 ? -49.15307  -24.15735 -115.49266 1.000 18.46752  ? 285 ILE   A CB  1 
ATOM   2334 C CG1 . ILE   A 1 285 ? -48.94024  -23.07139 -116.54946 1.000 13.05639  ? 285 ILE   A CG1 1 
ATOM   2335 C CG2 . ILE   A 1 285 ? -48.47424  -23.78537 -114.18769 1.000 13.40929  ? 285 ILE   A CG2 1 
ATOM   2336 C CD1 . ILE   A 1 285 ? -49.64375  -21.78393 -116.22084 1.000 11.87300  ? 285 ILE   A CD1 1 
ATOM   2337 N N   . GLN   A 1 286 ? -47.67997  -27.14519 -114.49281 1.000 22.33597  ? 286 GLN   A N   1 
ATOM   2338 C CA  . GLN   A 1 286 ? -47.74399  -28.21571 -113.51688 1.000 21.66253  ? 286 GLN   A CA  1 
ATOM   2339 C C   . GLN   A 1 286 ? -47.32214  -27.79593 -112.12127 1.000 21.34989  ? 286 GLN   A C   1 
ATOM   2340 O O   . GLN   A 1 286 ? -47.52360  -28.57010 -111.17883 1.000 25.51830  ? 286 GLN   A O   1 
ATOM   2341 C CB  . GLN   A 1 286 ? -46.89676  -29.40857 -113.97951 1.000 20.43567  ? 286 GLN   A CB  1 
ATOM   2342 C CG  . GLN   A 1 286 ? -47.43366  -30.08412 -115.28113 1.000 36.10906  ? 286 GLN   A CG  1 
ATOM   2343 C CD  . GLN   A 1 286 ? -48.98837  -30.23317 -115.36548 1.000 41.47356  ? 286 GLN   A CD  1 
ATOM   2344 O OE1 . GLN   A 1 286 ? -49.68635  -30.46483 -114.35924 1.000 37.46819  ? 286 GLN   A OE1 1 
ATOM   2345 N NE2 . GLN   A 1 286 ? -49.51987  -30.11246 -116.58926 1.000 38.65988  ? 286 GLN   A NE2 1 
ATOM   2346 N N   . SER   A 1 287 ? -46.78534  -26.58948 -111.95019 1.000 18.04338  ? 287 SER   A N   1 
ATOM   2347 C CA  . SER   A 1 287 ? -46.28998  -26.18174 -110.64397 1.000 19.36775  ? 287 SER   A CA  1 
ATOM   2348 C C   . SER   A 1 287 ? -46.11120  -24.67183 -110.61688 1.000 16.25422  ? 287 SER   A C   1 
ATOM   2349 O O   . SER   A 1 287 ? -45.63067  -24.07442 -111.58628 1.000 17.31166  ? 287 SER   A O   1 
ATOM   2350 C CB  . SER   A 1 287 ? -44.96536  -26.88248 -110.31719 1.000 16.20163  ? 287 SER   A CB  1 
ATOM   2351 O OG  . SER   A 1 287 ? -44.41827  -26.39055 -109.11889 1.000 16.47955  ? 287 SER   A OG  1 
ATOM   2352 N N   . VAL   A 1 288 ? -46.49656  -24.06776 -109.49795 1.000 16.32329  ? 288 VAL   A N   1 
ATOM   2353 C CA  . VAL   A 1 288 ? -46.36659  -22.63496 -109.27724 1.000 14.57846  ? 288 VAL   A CA  1 
ATOM   2354 C C   . VAL   A 1 288 ? -45.65308  -22.44814 -107.94708 1.000 17.55757  ? 288 VAL   A C   1 
ATOM   2355 O O   . VAL   A 1 288 ? -46.22743  -22.72697 -106.88607 1.000 17.04423  ? 288 VAL   A O   1 
ATOM   2356 C CB  . VAL   A 1 288 ? -47.72283  -21.92355 -109.26420 1.000 15.40640  ? 288 VAL   A CB  1 
ATOM   2357 C CG1 . VAL   A 1 288 ? -47.53122  -20.45406 -108.92142 1.000 13.61505  ? 288 VAL   A CG1 1 
ATOM   2358 C CG2 . VAL   A 1 288 ? -48.43324  -22.08609 -110.61607 1.000 12.56571  ? 288 VAL   A CG2 1 
ATOM   2359 N N   . THR   A 1 289 ? -44.41304  -21.97160 -107.99853 1.000 13.80865  ? 289 THR   A N   1 
ATOM   2360 C CA  . THR   A 1 289 ? -43.58963  -21.75255 -106.81798 1.000 13.93498  ? 289 THR   A CA  1 
ATOM   2361 C C   . THR   A 1 289 ? -43.40899  -20.25805 -106.59607 1.000 15.75415  ? 289 THR   A C   1 
ATOM   2362 O O   . THR   A 1 289 ? -42.99434  -19.53684 -107.51342 1.000 16.29300  ? 289 THR   A O   1 
ATOM   2363 C CB  . THR   A 1 289 ? -42.21585  -22.41333 -106.97377 1.000 13.15551  ? 289 THR   A CB  1 
ATOM   2364 O OG1 . THR   A 1 289 ? -42.38065  -23.82682 -107.12394 1.000 12.04704  ? 289 THR   A OG1 1 
ATOM   2365 C CG2 . THR   A 1 289 ? -41.33571  -22.11252 -105.75951 1.000 10.55167  ? 289 THR   A CG2 1 
ATOM   2366 N N   . PHE   A 1 290 ? -43.71657  -19.80219 -105.38326 1.000 13.32554  ? 290 PHE   A N   1 
ATOM   2367 C CA  . PHE   A 1 290 ? -43.37754  -18.45065 -104.96001 1.000 17.19571  ? 290 PHE   A CA  1 
ATOM   2368 C C   . PHE   A 1 290 ? -41.91956  -18.38088 -104.51780 1.000 17.69823  ? 290 PHE   A C   1 
ATOM   2369 O O   . PHE   A 1 290 ? -41.40446  -19.29665 -103.86885 1.000 20.43214  ? 290 PHE   A O   1 
ATOM   2370 C CB  . PHE   A 1 290 ? -44.26418  -18.01634 -103.79128 1.000 17.72867  ? 290 PHE   A CB  1 
ATOM   2371 C CG  . PHE   A 1 290 ? -45.72815  -18.01029 -104.09460 1.000 19.99216  ? 290 PHE   A CG  1 
ATOM   2372 C CD1 . PHE   A 1 290 ? -46.47112  -19.18140 -104.03003 1.000 20.87404  ? 290 PHE   A CD1 1 
ATOM   2373 C CD2 . PHE   A 1 290 ? -46.37584  -16.82176 -104.40325 1.000 16.21706  ? 290 PHE   A CD2 1 
ATOM   2374 C CE1 . PHE   A 1 290 ? -47.83483  -19.17547 -104.28689 1.000 24.18211  ? 290 PHE   A CE1 1 
ATOM   2375 C CE2 . PHE   A 1 290 ? -47.73437  -16.80358 -104.65682 1.000 15.53242  ? 290 PHE   A CE2 1 
ATOM   2376 C CZ  . PHE   A 1 290 ? -48.46788  -17.98413 -104.60220 1.000 21.47527  ? 290 PHE   A CZ  1 
ATOM   2377 N N   . TRP   A 1 291 ? -41.25986  -17.26648 -104.81070 1.000 15.71265  ? 291 TRP   A N   1 
ATOM   2378 C CA  . TRP   A 1 291 ? -39.89895  -17.08741 -104.31495 1.000 13.08107  ? 291 TRP   A CA  1 
ATOM   2379 C C   . TRP   A 1 291 ? -39.93061  -16.59965 -102.85828 1.000 16.94013  ? 291 TRP   A C   1 
ATOM   2380 O O   . TRP   A 1 291 ? -39.49914  -15.49677 -102.51129 1.000 15.54431  ? 291 TRP   A O   1 
ATOM   2381 C CB  . TRP   A 1 291 ? -39.12089  -16.14875 -105.22301 1.000 13.57715  ? 291 TRP   A CB  1 
ATOM   2382 C CG  . TRP   A 1 291 ? -37.66112  -16.48040 -105.21095 1.000 13.71877  ? 291 TRP   A CG  1 
ATOM   2383 C CD1 . TRP   A 1 291 ? -36.64242  -15.69869 -104.74722 1.000 13.21796  ? 291 TRP   A CD1 1 
ATOM   2384 C CD2 . TRP   A 1 291 ? -37.06191  -17.70571 -105.65161 1.000 13.77245  ? 291 TRP   A CD2 1 
ATOM   2385 N NE1 . TRP   A 1 291 ? -35.44243  -16.34590 -104.89936 1.000 15.73354  ? 291 TRP   A NE1 1 
ATOM   2386 C CE2 . TRP   A 1 291 ? -35.67186  -17.58576 -105.44372 1.000 17.02240  ? 291 TRP   A CE2 1 
ATOM   2387 C CE3 . TRP   A 1 291 ? -37.56575  -18.88729 -106.21575 1.000 9.66870   ? 291 TRP   A CE3 1 
ATOM   2388 C CZ2 . TRP   A 1 291 ? -34.77733  -18.60607 -105.77068 1.000 13.90132  ? 291 TRP   A CZ2 1 
ATOM   2389 C CZ3 . TRP   A 1 291 ? -36.68143  -19.89568 -106.54369 1.000 18.92864  ? 291 TRP   A CZ3 1 
ATOM   2390 C CH2 . TRP   A 1 291 ? -35.29510  -19.74904 -106.32438 1.000 16.68694  ? 291 TRP   A CH2 1 
ATOM   2391 N N   . GLY   A 1 292 ? -40.42055  -17.48308 -101.97572 1.000 14.91243  ? 292 GLY   A N   1 
ATOM   2392 C CA  . GLY   A 1 292 ? -40.69973  -17.18757 -100.58804 1.000 10.71280  ? 292 GLY   A CA  1 
ATOM   2393 C C   . GLY   A 1 292 ? -42.09173  -17.66709 -100.26287 1.000 14.61850  ? 292 GLY   A C   1 
ATOM   2394 O O   . GLY   A 1 292 ? -42.68700  -18.43608 -101.02373 1.000 18.27557  ? 292 GLY   A O   1 
ATOM   2395 N N   . ILE   A 1 293 ? -42.64640  -17.21671 -99.13129  1.000 14.23212  ? 293 ILE   A N   1 
ATOM   2396 C CA  . ILE   A 1 293 ? -44.05168  -17.52025 -98.87476  1.000 14.81716  ? 293 ILE   A CA  1 
ATOM   2397 C C   . ILE   A 1 293 ? -44.78659  -16.40899 -98.12196  1.000 20.55317  ? 293 ILE   A C   1 
ATOM   2398 O O   . ILE   A 1 293 ? -45.99751  -16.22105 -98.32039  1.000 20.44457  ? 293 ILE   A O   1 
ATOM   2399 C CB  . ILE   A 1 293 ? -44.20877  -18.86535 -98.14152  1.000 13.94523  ? 293 ILE   A CB  1 
ATOM   2400 C CG1 . ILE   A 1 293 ? -45.70288  -19.22612 -98.08028  1.000 12.88154  ? 293 ILE   A CG1 1 
ATOM   2401 C CG2 . ILE   A 1 293 ? -43.56116  -18.81916 -96.74599  1.000 10.27860  ? 293 ILE   A CG2 1 
ATOM   2402 C CD1 . ILE   A 1 293 ? -45.99406  -20.68725 -97.81778  1.000 25.32527  ? 293 ILE   A CD1 1 
ATOM   2403 N N   . ALA   A 1 294 ? -44.09071  -15.67431 -97.24714  1.000 15.49417  ? 294 ALA   A N   1 
ATOM   2404 C CA  . ALA   A 1 294 ? -44.71843  -14.56592 -96.53010  1.000 15.62450  ? 294 ALA   A CA  1 
ATOM   2405 C C   . ALA   A 1 294 ? -43.78977  -13.36495 -96.53154  1.000 18.60822  ? 294 ALA   A C   1 
ATOM   2406 O O   . ALA   A 1 294 ? -42.58085  -13.49034 -96.73255  1.000 15.86587  ? 294 ALA   A O   1 
ATOM   2407 C CB  . ALA   A 1 294 ? -45.08738  -14.93069 -95.09167  1.000 18.86608  ? 294 ALA   A CB  1 
ATOM   2408 N N   . ASP   A 1 295 ? -44.36775  -12.18789 -96.27998  1.000 17.99417  ? 295 ASP   A N   1 
ATOM   2409 C CA  . ASP   A 1 295 ? -43.61752  -10.95448 -96.48617  1.000 20.02920  ? 295 ASP   A CA  1 
ATOM   2410 C C   . ASP   A 1 295 ? -42.52785  -10.71386 -95.43436  1.000 21.99445  ? 295 ASP   A C   1 
ATOM   2411 O O   . ASP   A 1 295 ? -41.74997  -9.76033  -95.58271  1.000 16.45758  ? 295 ASP   A O   1 
ATOM   2412 C CB  . ASP   A 1 295 ? -44.59215  -9.76862  -96.55053  1.000 22.46702  ? 295 ASP   A CB  1 
ATOM   2413 C CG  . ASP   A 1 295 ? -45.43363  -9.75395  -97.84646  1.000 24.87454  ? 295 ASP   A CG  1 
ATOM   2414 O OD1 . ASP   A 1 295 ? -45.14743  -10.53640 -98.77786  1.000 19.37502  ? 295 ASP   A OD1 1 
ATOM   2415 O OD2 . ASP   A 1 295 ? -46.39029  -8.95081  -97.93394  1.000 21.33950  ? 295 ASP   A OD2 1 
ATOM   2416 N N   . ASP   A 1 296 ? -42.42486  -11.54460 -94.39131  1.000 19.42834  ? 296 ASP   A N   1 
ATOM   2417 C CA  . ASP   A 1 296 ? -41.29544  -11.37529 -93.47331  1.000 21.31934  ? 296 ASP   A CA  1 
ATOM   2418 C C   . ASP   A 1 296 ? -39.96979  -11.84995 -94.05535  1.000 16.82321  ? 296 ASP   A C   1 
ATOM   2419 O O   . ASP   A 1 296 ? -38.92215  -11.54087 -93.48533  1.000 22.95934  ? 296 ASP   A O   1 
ATOM   2420 C CB  . ASP   A 1 296 ? -41.53091  -12.09217 -92.13439  1.000 22.88954  ? 296 ASP   A CB  1 
ATOM   2421 C CG  . ASP   A 1 296 ? -41.95531  -13.54173 -92.29129  1.000 23.93164  ? 296 ASP   A CG  1 
ATOM   2422 O OD1 . ASP   A 1 296 ? -42.49437  -13.92294 -93.35260  1.000 28.72080  ? 296 ASP   A OD1 1 
ATOM   2423 O OD2 . ASP   A 1 296 ? -41.77208  -14.30047 -91.32195  1.000 27.00300  ? 296 ASP   A OD2 1 
ATOM   2424 N N   . HIS   A 1 297 ? -39.96814  -12.58334 -95.16319  1.000 18.66349  ? 297 HIS   A N   1 
ATOM   2425 C CA  . HIS   A 1 297 ? -38.71395  -12.87013 -95.84948  1.000 22.10961  ? 297 HIS   A CA  1 
ATOM   2426 C C   . HIS   A 1 297 ? -38.93381  -12.78955 -97.34949  1.000 20.32778  ? 297 HIS   A C   1 
ATOM   2427 O O   . HIS   A 1 297 ? -39.71040  -13.57070 -97.90888  1.000 15.25729  ? 297 HIS   A O   1 
ATOM   2428 C CB  . HIS   A 1 297 ? -38.15677  -14.24463 -95.46721  1.000 22.54503  ? 297 HIS   A CB  1 
ATOM   2429 C CG  . HIS   A 1 297 ? -37.00383  -14.68127 -96.31783  1.000 26.73251  ? 297 HIS   A CG  1 
ATOM   2430 N ND1 . HIS   A 1 297 ? -35.69153  -14.39507 -95.99744  1.000 22.49878  ? 297 HIS   A ND1 1 
ATOM   2431 C CD2 . HIS   A 1 297 ? -36.96673  -15.36628 -97.48908  1.000 19.98622  ? 297 HIS   A CD2 1 
ATOM   2432 C CE1 . HIS   A 1 297 ? -34.89538  -14.89155 -96.92848  1.000 20.94099  ? 297 HIS   A CE1 1 
ATOM   2433 N NE2 . HIS   A 1 297 ? -35.64219  -15.48818 -97.84250  1.000 32.33678  ? 297 HIS   A NE2 1 
ATOM   2434 N N   . THR   A 1 298 ? -38.23126  -11.86655 -97.99625  1.000 17.08406  ? 298 THR   A N   1 
ATOM   2435 C CA  . THR   A 1 298 ? -38.23071  -11.77896 -99.44704  1.000 18.85661  ? 298 THR   A CA  1 
ATOM   2436 C C   . THR   A 1 298 ? -36.92382  -11.13468 -99.89159  1.000 22.09313  ? 298 THR   A C   1 
ATOM   2437 O O   . THR   A 1 298 ? -36.47436  -10.13987 -99.31306  1.000 17.61974  ? 298 THR   A O   1 
ATOM   2438 C CB  . THR   A 1 298 ? -39.43307  -10.97660 -99.97277  1.000 15.44556  ? 298 THR   A CB  1 
ATOM   2439 O OG1 . THR   A 1 298 ? -39.29953  -10.77759 -101.38724 1.000 13.26119  ? 298 THR   A OG1 1 
ATOM   2440 C CG2 . THR   A 1 298 ? -39.53625  -9.61528  -99.26542  1.000 14.06786  ? 298 THR   A CG2 1 
ATOM   2441 N N   . TRP   A 1 299 ? -36.31666  -11.71715 -100.92350 1.000 20.29209  ? 299 TRP   A N   1 
ATOM   2442 C CA  . TRP   A 1 299 ? -35.12192  -11.12837 -101.50451 1.000 13.89692  ? 299 TRP   A CA  1 
ATOM   2443 C C   . TRP   A 1 299 ? -35.39526  -9.74676  -102.07496 1.000 20.60300  ? 299 TRP   A C   1 
ATOM   2444 O O   . TRP   A 1 299 ? -34.44144  -8.99249  -102.31992 1.000 16.91788  ? 299 TRP   A O   1 
ATOM   2445 C CB  . TRP   A 1 299 ? -34.57826  -12.04007 -102.60031 1.000 17.11077  ? 299 TRP   A CB  1 
ATOM   2446 C CG  . TRP   A 1 299 ? -35.40108  -11.99262 -103.86468 1.000 13.43015  ? 299 TRP   A CG  1 
ATOM   2447 C CD1 . TRP   A 1 299 ? -36.73910  -12.29195 -104.00287 1.000 17.24276  ? 299 TRP   A CD1 1 
ATOM   2448 C CD2 . TRP   A 1 299 ? -34.93791  -11.62596 -105.16282 1.000 15.58439  ? 299 TRP   A CD2 1 
ATOM   2449 N NE1 . TRP   A 1 299 ? -37.12570  -12.13154 -105.32091 1.000 16.33157  ? 299 TRP   A NE1 1 
ATOM   2450 C CE2 . TRP   A 1 299 ? -36.03579  -11.72464 -106.04828 1.000 16.56676  ? 299 TRP   A CE2 1 
ATOM   2451 C CE3 . TRP   A 1 299 ? -33.69384  -11.23853 -105.67078 1.000 18.72982  ? 299 TRP   A CE3 1 
ATOM   2452 C CZ2 . TRP   A 1 299 ? -35.92253  -11.43429 -107.40577 1.000 18.79521  ? 299 TRP   A CZ2 1 
ATOM   2453 C CZ3 . TRP   A 1 299 ? -33.58336  -10.96189 -107.01963 1.000 19.36716  ? 299 TRP   A CZ3 1 
ATOM   2454 C CH2 . TRP   A 1 299 ? -34.69459  -11.04639 -107.86937 1.000 18.50073  ? 299 TRP   A CH2 1 
ATOM   2455 N N   . LEU   A 1 300 ? -36.67504  -9.40177  -102.29932 1.000 16.03953  ? 300 LEU   A N   1 
ATOM   2456 C CA  . LEU   A 1 300 ? -37.01317  -8.09356  -102.84525 1.000 18.87501  ? 300 LEU   A CA  1 
ATOM   2457 C C   . LEU   A 1 300 ? -36.82531  -6.96707  -101.83192 1.000 22.67635  ? 300 LEU   A C   1 
ATOM   2458 O O   . LEU   A 1 300 ? -36.77538  -5.79970  -102.23762 1.000 20.54810  ? 300 LEU   A O   1 
ATOM   2459 C CB  . LEU   A 1 300 ? -38.43858  -8.10675  -103.38530 1.000 16.46338  ? 300 LEU   A CB  1 
ATOM   2460 C CG  . LEU   A 1 300 ? -38.63534  -8.99756  -104.62479 1.000 16.74400  ? 300 LEU   A CG  1 
ATOM   2461 C CD1 . LEU   A 1 300 ? -40.07719  -8.94137  -105.15121 1.000 14.56891  ? 300 LEU   A CD1 1 
ATOM   2462 C CD2 . LEU   A 1 300 ? -37.66497  -8.61458  -105.71168 1.000 14.43465  ? 300 LEU   A CD2 1 
ATOM   2463 N N   . ASP   A 1 301 ? -36.68181  -7.28957  -100.54053 1.000 20.13990  ? 301 ASP   A N   1 
ATOM   2464 C CA  . ASP   A 1 301 ? -36.25498  -6.28989  -99.56187  1.000 24.05273  ? 301 ASP   A CA  1 
ATOM   2465 C C   . ASP   A 1 301 ? -34.94176  -5.63288  -99.97063  1.000 23.08687  ? 301 ASP   A C   1 
ATOM   2466 O O   . ASP   A 1 301 ? -34.73428  -4.44003  -99.72001  1.000 25.11582  ? 301 ASP   A O   1 
ATOM   2467 C CB  . ASP   A 1 301 ? -36.09438  -6.92417  -98.18104  1.000 16.14456  ? 301 ASP   A CB  1 
ATOM   2468 C CG  . ASP   A 1 301 ? -37.40995  -7.24070  -97.52679  1.000 25.19520  ? 301 ASP   A CG  1 
ATOM   2469 O OD1 . ASP   A 1 301 ? -38.44723  -6.68512  -97.94367  1.000 24.29504  ? 301 ASP   A OD1 1 
ATOM   2470 O OD2 . ASP   A 1 301 ? -37.40522  -8.05151  -96.57980  1.000 30.94684  ? 301 ASP   A OD2 1 
ATOM   2471 N N   . ASN   A 1 302 ? -34.03723  -6.38730  -100.59900 1.000 18.44338  ? 302 ASN   A N   1 
ATOM   2472 C CA  . ASN   A 1 302 ? -32.71610  -5.85958  -100.90534 1.000 20.24106  ? 302 ASN   A CA  1 
ATOM   2473 C C   . ASN   A 1 302 ? -32.38181  -5.85240  -102.37812 1.000 25.63981  ? 302 ASN   A C   1 
ATOM   2474 O O   . ASN   A 1 302 ? -31.26611  -5.45286  -102.74173 1.000 27.78977  ? 302 ASN   A O   1 
ATOM   2475 C CB  . ASN   A 1 302 ? -31.63567  -6.63725  -100.14713 1.000 22.08677  ? 302 ASN   A CB  1 
ATOM   2476 C CG  . ASN   A 1 302 ? -31.61717  -6.28069  -98.69122  1.000 27.15429  ? 302 ASN   A CG  1 
ATOM   2477 O OD1 . ASN   A 1 302 ? -31.26710  -5.16106  -98.33727  1.000 33.66525  ? 302 ASN   A OD1 1 
ATOM   2478 N ND2 . ASN   A 1 302 ? -32.04003  -7.21036  -97.83360  1.000 22.34858  ? 302 ASN   A ND2 1 
ATOM   2479 N N   . PHE   A 1 303 ? -33.29173  -6.29716  -103.23116 1.000 20.56578  ? 303 PHE   A N   1 
ATOM   2480 C CA  . PHE   A 1 303 ? -33.06166  -6.20190  -104.65867 1.000 27.30776  ? 303 PHE   A CA  1 
ATOM   2481 C C   . PHE   A 1 303 ? -34.31923  -5.66289  -105.32092 1.000 24.01795  ? 303 PHE   A C   1 
ATOM   2482 O O   . PHE   A 1 303 ? -35.43137  -6.09682  -104.98399 1.000 23.38812  ? 303 PHE   A O   1 
ATOM   2483 C CB  . PHE   A 1 303 ? -32.69884  -7.56067  -105.27408 1.000 20.35276  ? 303 PHE   A CB  1 
ATOM   2484 C CG  . PHE   A 1 303 ? -32.52424  -7.51777  -106.76794 1.000 25.18790  ? 303 PHE   A CG  1 
ATOM   2485 C CD1 . PHE   A 1 303 ? -31.28491  -7.21685  -107.32579 1.000 30.81672  ? 303 PHE   A CD1 1 
ATOM   2486 C CD2 . PHE   A 1 303 ? -33.59915  -7.75815  -107.61982 1.000 24.96077  ? 303 PHE   A CD2 1 
ATOM   2487 C CE1 . PHE   A 1 303 ? -31.11357  -7.16707  -108.70591 1.000 38.00526  ? 303 PHE   A CE1 1 
ATOM   2488 C CE2 . PHE   A 1 303 ? -33.43688  -7.71580  -109.00410 1.000 25.07386  ? 303 PHE   A CE2 1 
ATOM   2489 C CZ  . PHE   A 1 303 ? -32.19328  -7.41820  -109.54735 1.000 33.48480  ? 303 PHE   A CZ  1 
ATOM   2490 N N   . PRO   A 1 304 ? -34.17837  -4.72800  -106.27484 1.000 26.09454  ? 304 PRO   A N   1 
ATOM   2491 C CA  . PRO   A 1 304 ? -32.89217  -4.15013  -106.72095 1.000 26.38847  ? 304 PRO   A CA  1 
ATOM   2492 C C   . PRO   A 1 304 ? -32.39021  -2.96669  -105.89161 1.000 28.24052  ? 304 PRO   A C   1 
ATOM   2493 O O   . PRO   A 1 304 ? -31.38990  -2.35710  -106.25925 1.000 31.07863  ? 304 PRO   A O   1 
ATOM   2494 C CB  . PRO   A 1 304 ? -33.19647  -3.68301  -108.15031 1.000 24.35322  ? 304 PRO   A CB  1 
ATOM   2495 C CG  . PRO   A 1 304 ? -34.66770  -3.36208  -108.11785 1.000 27.11343  ? 304 PRO   A CG  1 
ATOM   2496 C CD  . PRO   A 1 304 ? -35.30039  -4.33500  -107.14953 1.000 18.11248  ? 304 PRO   A CD  1 
ATOM   2497 N N   . VAL   A 1 305 ? -33.08425  -2.63255  -104.81029 1.000 29.65874  ? 305 VAL   A N   1 
ATOM   2498 C CA  . VAL   A 1 305 ? -32.68896  -1.55698  -103.91294 1.000 28.24747  ? 305 VAL   A CA  1 
ATOM   2499 C C   . VAL   A 1 305 ? -32.27430  -2.18670  -102.59644 1.000 31.45189  ? 305 VAL   A C   1 
ATOM   2500 O O   . VAL   A 1 305 ? -33.09724  -2.81325  -101.91426 1.000 25.13908  ? 305 VAL   A O   1 
ATOM   2501 C CB  . VAL   A 1 305 ? -33.82111  -0.54338  -103.68465 1.000 36.06048  ? 305 VAL   A CB  1 
ATOM   2502 C CG1 . VAL   A 1 305 ? -33.34278  0.57027   -102.76897 1.000 32.79891  ? 305 VAL   A CG1 1 
ATOM   2503 C CG2 . VAL   A 1 305 ? -34.31190  0.02409   -104.99130 1.000 27.50012  ? 305 VAL   A CG2 1 
ATOM   2504 N N   . HIS   A 1 306 ? -31.00963  -2.01007  -102.22259 1.000 30.32542  ? 306 HIS   A N   1 
ATOM   2505 C CA  . HIS   A 1 306 ? -30.58565  -2.53786  -100.93880 1.000 28.88112  ? 306 HIS   A CA  1 
ATOM   2506 C C   . HIS   A 1 306 ? -31.26444  -1.79556  -99.79240  1.000 31.20376  ? 306 HIS   A C   1 
ATOM   2507 O O   . HIS   A 1 306 ? -31.41046  -0.57005  -99.81369  1.000 28.69652  ? 306 HIS   A O   1 
ATOM   2508 C CB  . HIS   A 1 306 ? -29.07014  -2.46510  -100.76992 1.000 31.18696  ? 306 HIS   A CB  1 
ATOM   2509 C CG  . HIS   A 1 306 ? -28.59426  -3.23917  -99.58093  1.000 48.76725  ? 306 HIS   A CG  1 
ATOM   2510 N ND1 . HIS   A 1 306 ? -28.59913  -2.71589  -98.30255  1.000 50.14779  ? 306 HIS   A ND1 1 
ATOM   2511 C CD2 . HIS   A 1 306 ? -28.20430  -4.53155  -99.45620  1.000 47.56436  ? 306 HIS   A CD2 1 
ATOM   2512 C CE1 . HIS   A 1 306 ? -28.18385  -3.63629  -97.44966  1.000 42.05748  ? 306 HIS   A CE1 1 
ATOM   2513 N NE2 . HIS   A 1 306 ? -27.93861  -4.74735  -98.12341  1.000 54.66617  ? 306 HIS   A NE2 1 
ATOM   2514 N N   . GLY   A 1 307 ? -31.69973  -2.55365  -98.79272  1.000 28.78760  ? 307 GLY   A N   1 
ATOM   2515 C CA  . GLY   A 1 307 ? -32.08976  -1.95993  -97.53355  1.000 23.81564  ? 307 GLY   A CA  1 
ATOM   2516 C C   . GLY   A 1 307 ? -33.46866  -1.35230  -97.47805  1.000 31.86004  ? 307 GLY   A C   1 
ATOM   2517 O O   . GLY   A 1 307 ? -33.73081  -0.53374  -96.59246  1.000 33.64722  ? 307 GLY   A O   1 
ATOM   2518 N N   . ARG   A 1 308 ? -34.36936  -1.72001  -98.38498  1.000 30.42124  ? 308 ARG   A N   1 
ATOM   2519 C CA  . ARG   A 1 308 ? -35.73888  -1.26277  -98.22997  1.000 28.55469  ? 308 ARG   A CA  1 
ATOM   2520 C C   . ARG   A 1 308 ? -36.62896  -2.44276  -97.84345  1.000 27.36463  ? 308 ARG   A C   1 
ATOM   2521 O O   . ARG   A 1 308 ? -36.13927  -3.48789  -97.39976  1.000 37.99239  ? 308 ARG   A O   1 
ATOM   2522 C CB  . ARG   A 1 308 ? -36.20835  -0.53942  -99.49712  1.000 29.28031  ? 308 ARG   A CB  1 
ATOM   2523 C CG  . ARG   A 1 308 ? -36.45861  -1.39984  -100.71027 1.000 25.78159  ? 308 ARG   A CG  1 
ATOM   2524 C CD  . ARG   A 1 308 ? -37.10735  -0.57100  -101.84845 1.000 26.31393  ? 308 ARG   A CD  1 
ATOM   2525 N NE  . ARG   A 1 308 ? -37.23829  -1.36041  -103.07059 1.000 29.54171  ? 308 ARG   A NE  1 
ATOM   2526 C CZ  . ARG   A 1 308 ? -37.52314  -0.87105  -104.27016 1.000 29.06159  ? 308 ARG   A CZ  1 
ATOM   2527 N NH1 . ARG   A 1 308 ? -37.72627  0.43485   -104.42602 1.000 20.42814  ? 308 ARG   A NH1 1 
ATOM   2528 N NH2 . ARG   A 1 308 ? -37.60999  -1.70216  -105.31418 1.000 21.42679  ? 308 ARG   A NH2 1 
ATOM   2529 N N   . LYS   A 1 309 ? -37.92795  -2.26508  -97.97797  1.000 19.35856  ? 309 LYS   A N   1 
ATOM   2530 C CA  . LYS   A 1 309 ? -38.87789  -3.29954  -97.63938  1.000 23.29775  ? 309 LYS   A CA  1 
ATOM   2531 C C   . LYS   A 1 309 ? -39.87517  -3.44469  -98.78184  1.000 26.10657  ? 309 LYS   A C   1 
ATOM   2532 O O   . LYS   A 1 309 ? -40.31985  -2.45049  -99.35820  1.000 23.67640  ? 309 LYS   A O   1 
ATOM   2533 C CB  . LYS   A 1 309 ? -39.59010  -2.97021  -96.32178  1.000 16.20208  ? 309 LYS   A CB  1 
ATOM   2534 C CG  . LYS   A 1 309 ? -40.43400  -4.11013  -95.77854  1.000 19.41703  ? 309 LYS   A CG  1 
ATOM   2535 C CD  . LYS   A 1 309 ? -39.56829  -5.19471  -95.13970  1.000 22.20922  ? 309 LYS   A CD  1 
ATOM   2536 C CE  . LYS   A 1 309 ? -40.36560  -6.46948  -94.90752  1.000 21.87935  ? 309 LYS   A CE  1 
ATOM   2537 N NZ  . LYS   A 1 309 ? -40.48377  -7.28430  -96.15121  1.000 21.15111  ? 309 LYS   A NZ  1 
ATOM   2538 N N   . ASN   A 1 310 ? -40.20714  -4.68842  -99.11728  1.000 22.13682  ? 310 ASN   A N   1 
ATOM   2539 C CA  . ASN   A 1 310 ? -41.18439  -4.99477  -100.14499 1.000 18.35222  ? 310 ASN   A CA  1 
ATOM   2540 C C   . ASN   A 1 310 ? -42.21902  -5.93317  -99.54267  1.000 21.34140  ? 310 ASN   A C   1 
ATOM   2541 O O   . ASN   A 1 310 ? -42.00129  -6.52862  -98.48659  1.000 23.02294  ? 310 ASN   A O   1 
ATOM   2542 C CB  . ASN   A 1 310 ? -40.52213  -5.61548  -101.38139 1.000 22.87159  ? 310 ASN   A CB  1 
ATOM   2543 C CG  . ASN   A 1 310 ? -41.24093  -5.26350  -102.67214 1.000 24.04516  ? 310 ASN   A CG  1 
ATOM   2544 O OD1 . ASN   A 1 310 ? -42.47159  -5.18586  -102.71126 1.000 24.44335  ? 310 ASN   A OD1 1 
ATOM   2545 N ND2 . ASN   A 1 310 ? -40.47239  -5.05956  -103.74349 1.000 20.06717  ? 310 ASN   A ND2 1 
ATOM   2546 N N   . TRP   A 1 311 ? -43.37321  -6.03223  -100.19290 1.000 22.10501  ? 311 TRP   A N   1 
ATOM   2547 C CA  . TRP   A 1 311 ? -44.50083  -6.80745  -99.66878  1.000 18.74499  ? 311 TRP   A CA  1 
ATOM   2548 C C   . TRP   A 1 311 ? -45.10475  -7.60308  -100.81266 1.000 20.10280  ? 311 TRP   A C   1 
ATOM   2549 O O   . TRP   A 1 311 ? -46.21098  -7.30944  -101.28416 1.000 20.62476  ? 311 TRP   A O   1 
ATOM   2550 C CB  . TRP   A 1 311 ? -45.52884  -5.88811  -99.00624  1.000 20.76613  ? 311 TRP   A CB  1 
ATOM   2551 C CG  . TRP   A 1 311 ? -44.89814  -4.94028  -98.03803  1.000 27.51670  ? 311 TRP   A CG  1 
ATOM   2552 C CD1 . TRP   A 1 311 ? -44.72651  -5.13295  -96.70035  1.000 21.47754  ? 311 TRP   A CD1 1 
ATOM   2553 C CD2 . TRP   A 1 311 ? -44.33907  -3.64837  -98.33286  1.000 20.44865  ? 311 TRP   A CD2 1 
ATOM   2554 N NE1 . TRP   A 1 311 ? -44.10040  -4.04644  -96.14609  1.000 21.50415  ? 311 TRP   A NE1 1 
ATOM   2555 C CE2 . TRP   A 1 311 ? -43.84859  -3.12237  -97.12362  1.000 20.69611  ? 311 TRP   A CE2 1 
ATOM   2556 C CE3 . TRP   A 1 311 ? -44.20410  -2.89397  -99.50025  1.000 21.36578  ? 311 TRP   A CE3 1 
ATOM   2557 C CZ2 . TRP   A 1 311 ? -43.23825  -1.87157  -97.04244  1.000 23.23827  ? 311 TRP   A CZ2 1 
ATOM   2558 C CZ3 . TRP   A 1 311 ? -43.60498  -1.65453  -99.42168  1.000 24.29258  ? 311 TRP   A CZ3 1 
ATOM   2559 C CH2 . TRP   A 1 311 ? -43.12537  -1.15529  -98.19852  1.000 27.56680  ? 311 TRP   A CH2 1 
ATOM   2560 N N   . PRO   A 1 312 ? -44.40243  -8.64028  -101.27155 1.000 20.12848  ? 312 PRO   A N   1 
ATOM   2561 C CA  . PRO   A 1 312 ? -44.68606  -9.24855  -102.58153 1.000 11.92904  ? 312 PRO   A CA  1 
ATOM   2562 C C   . PRO   A 1 312 ? -45.51834  -10.51953 -102.57562 1.000 16.76317  ? 312 PRO   A C   1 
ATOM   2563 O O   . PRO   A 1 312 ? -45.81413  -11.01946 -103.66602 1.000 15.15365  ? 312 PRO   A O   1 
ATOM   2564 C CB  . PRO   A 1 312 ? -43.27337  -9.56812  -103.08901 1.000 21.25446  ? 312 PRO   A CB  1 
ATOM   2565 C CG  . PRO   A 1 312 ? -42.30247  -9.13563  -101.96325 1.000 17.33657  ? 312 PRO   A CG  1 
ATOM   2566 C CD  . PRO   A 1 312 ? -43.11296  -9.10221  -100.74317 1.000 12.99921  ? 312 PRO   A CD  1 
ATOM   2567 N N   . LEU   A 1 313 ? -45.87895  -11.06029 -101.41614 1.000 13.93542  ? 313 LEU   A N   1 
ATOM   2568 C CA  . LEU   A 1 313 ? -46.40065  -12.41743 -101.33452 1.000 18.45889  ? 313 LEU   A CA  1 
ATOM   2569 C C   . LEU   A 1 313 ? -47.84238  -12.42100 -100.79661 1.000 22.30442  ? 313 LEU   A C   1 
ATOM   2570 O O   . LEU   A 1 313 ? -48.45566  -11.37209 -100.55933 1.000 17.87502  ? 313 LEU   A O   1 
ATOM   2571 C CB  . LEU   A 1 313 ? -45.44988  -13.27867 -100.49474 1.000 18.18048  ? 313 LEU   A CB  1 
ATOM   2572 C CG  . LEU   A 1 313 ? -44.03523  -13.35810 -101.11381 1.000 19.44545  ? 313 LEU   A CG  1 
ATOM   2573 C CD1 . LEU   A 1 313 ? -42.89892  -13.55575 -100.09278 1.000 11.21228  ? 313 LEU   A CD1 1 
ATOM   2574 C CD2 . LEU   A 1 313 ? -43.97938  -14.44979 -102.16181 1.000 17.10758  ? 313 LEU   A CD2 1 
ATOM   2575 N N   . LEU   A 1 314 ? -48.39066  -13.62914 -100.62230 1.000 18.69851  ? 314 LEU   A N   1 
ATOM   2576 C CA  . LEU   A 1 314 ? -49.79180  -13.79777 -100.24203 1.000 18.32080  ? 314 LEU   A CA  1 
ATOM   2577 C C   . LEU   A 1 314 ? -50.04873  -13.66306 -98.73740  1.000 19.40353  ? 314 LEU   A C   1 
ATOM   2578 O O   . LEU   A 1 314 ? -51.21089  -13.52002 -98.34069  1.000 23.60938  ? 314 LEU   A O   1 
ATOM   2579 C CB  . LEU   A 1 314 ? -50.29733  -15.16011 -100.70417 1.000 12.97463  ? 314 LEU   A CB  1 
ATOM   2580 C CG  . LEU   A 1 314 ? -50.41457  -15.45707 -102.18506 1.000 14.42580  ? 314 LEU   A CG  1 
ATOM   2581 C CD1 . LEU   A 1 314 ? -51.13189  -16.77008 -102.34711 1.000 10.27135  ? 314 LEU   A CD1 1 
ATOM   2582 C CD2 . LEU   A 1 314 ? -51.13659  -14.33414 -102.93263 1.000 16.37970  ? 314 LEU   A CD2 1 
ATOM   2583 N N   . PHE   A 1 315 ? -49.01389  -13.72493 -97.89791  1.000 15.29830  ? 315 PHE   A N   1 
ATOM   2584 C CA  . PHE   A 1 315 ? -49.14994  -13.58028 -96.45659  1.000 14.36840  ? 315 PHE   A CA  1 
ATOM   2585 C C   . PHE   A 1 315 ? -48.24606  -12.45442 -95.97124  1.000 19.93451  ? 315 PHE   A C   1 
ATOM   2586 O O   . PHE   A 1 315 ? -47.17049  -12.21492 -96.53339  1.000 21.40894  ? 315 PHE   A O   1 
ATOM   2587 C CB  . PHE   A 1 315 ? -48.79467  -14.87289 -95.71897  1.000 21.58429  ? 315 PHE   A CB  1 
ATOM   2588 C CG  . PHE   A 1 315 ? -49.57730  -16.07092 -96.17037  1.000 19.51381  ? 315 PHE   A CG  1 
ATOM   2589 C CD1 . PHE   A 1 315 ? -50.79017  -16.38453 -95.57885  1.000 16.88344  ? 315 PHE   A CD1 1 
ATOM   2590 C CD2 . PHE   A 1 315 ? -49.09674  -16.88906 -97.18789  1.000 17.07641  ? 315 PHE   A CD2 1 
ATOM   2591 C CE1 . PHE   A 1 315 ? -51.51671  -17.49656 -95.99621  1.000 18.74869  ? 315 PHE   A CE1 1 
ATOM   2592 C CE2 . PHE   A 1 315 ? -49.81712  -18.00674 -97.61109  1.000 14.75539  ? 315 PHE   A CE2 1 
ATOM   2593 C CZ  . PHE   A 1 315 ? -51.03446  -18.30576 -97.01440  1.000 19.32893  ? 315 PHE   A CZ  1 
ATOM   2594 N N   . ASP   A 1 316 ? -48.69156  -11.75063 -94.93141  1.000 16.36922  ? 316 ASP   A N   1 
ATOM   2595 C CA  . ASP   A 1 316 ? -47.91150  -10.62762 -94.43146  1.000 23.01500  ? 316 ASP   A CA  1 
ATOM   2596 C C   . ASP   A 1 316 ? -46.83550  -11.11462 -93.46467  1.000 21.30071  ? 316 ASP   A C   1 
ATOM   2597 O O   . ASP   A 1 316 ? -46.65037  -12.31693 -93.24907  1.000 21.19010  ? 316 ASP   A O   1 
ATOM   2598 C CB  . ASP   A 1 316 ? -48.81235  -9.58611  -93.76927  1.000 21.42491  ? 316 ASP   A CB  1 
ATOM   2599 C CG  . ASP   A 1 316 ? -49.62578  -10.15197 -92.61965  1.000 32.55031  ? 316 ASP   A CG  1 
ATOM   2600 O OD1 . ASP   A 1 316 ? -49.17818  -11.12494 -91.93338  1.000 19.21077  ? 316 ASP   A OD1 1 
ATOM   2601 O OD2 . ASP   A 1 316 ? -50.73928  -9.60408  -92.42088  1.000 29.18479  ? 316 ASP   A OD2 1 
ATOM   2602 N N   . GLU   A 1 317 ? -46.12787  -10.15626 -92.85885  1.000 19.32171  ? 317 GLU   A N   1 
ATOM   2603 C CA  . GLU   A 1 317 ? -45.02072  -10.48621 -91.96961  1.000 24.06612  ? 317 GLU   A CA  1 
ATOM   2604 C C   . GLU   A 1 317 ? -45.48287  -11.20708 -90.71393  1.000 24.92766  ? 317 GLU   A C   1 
ATOM   2605 O O   . GLU   A 1 317 ? -44.68098  -11.89048 -90.07421  1.000 36.93450  ? 317 GLU   A O   1 
ATOM   2606 C CB  . GLU   A 1 317 ? -44.24822  -9.21565  -91.61510  1.000 22.61961  ? 317 GLU   A CB  1 
ATOM   2607 C CG  . GLU   A 1 317 ? -43.78833  -8.47684  -92.85848  1.000 21.51404  ? 317 GLU   A CG  1 
ATOM   2608 C CD  . GLU   A 1 317 ? -43.40774  -7.04003  -92.60501  1.000 32.44527  ? 317 GLU   A CD  1 
ATOM   2609 O OE1 . GLU   A 1 317 ? -42.33152  -6.80685  -91.99988  1.000 31.69118  ? 317 GLU   A OE1 1 
ATOM   2610 O OE2 . GLU   A 1 317 ? -44.18865  -6.14686  -93.01472  1.000 33.83203  ? 317 GLU   A OE2 1 
ATOM   2611 N N   . GLN   A 1 318 ? -46.74958  -11.09561 -90.35567  1.000 18.59048  ? 318 GLN   A N   1 
ATOM   2612 C CA  . GLN   A 1 318 ? -47.29317  -11.88080 -89.26264  1.000 24.06070  ? 318 GLN   A CA  1 
ATOM   2613 C C   . GLN   A 1 318 ? -47.89294  -13.19363 -89.74166  1.000 24.61926  ? 318 GLN   A C   1 
ATOM   2614 O O   . GLN   A 1 318 ? -48.59078  -13.85621 -88.97251  1.000 33.14180  ? 318 GLN   A O   1 
ATOM   2615 C CB  . GLN   A 1 318 ? -48.33325  -11.05475 -88.49328  1.000 26.29879  ? 318 GLN   A CB  1 
ATOM   2616 C CG  . GLN   A 1 318 ? -47.72544  -9.82518  -87.78794  1.000 26.18260  ? 318 GLN   A CG  1 
ATOM   2617 C CD  . GLN   A 1 318 ? -47.49107  -8.63468  -88.73680  1.000 38.72015  ? 318 GLN   A CD  1 
ATOM   2618 O OE1 . GLN   A 1 318 ? -48.37436  -8.26901  -89.52579  1.000 41.58111  ? 318 GLN   A OE1 1 
ATOM   2619 N NE2 . GLN   A 1 318 ? -46.30323  -8.02537  -88.65546  1.000 21.36732  ? 318 GLN   A NE2 1 
ATOM   2620 N N   . HIS   A 1 319 ? -47.63699  -13.58115 -90.99373  1.000 23.76447  ? 319 HIS   A N   1 
ATOM   2621 C CA  . HIS   A 1 319 ? -48.13096  -14.82781 -91.58629  1.000 24.91491  ? 319 HIS   A CA  1 
ATOM   2622 C C   . HIS   A 1 319 ? -49.65174  -14.85393 -91.70047  1.000 22.03447  ? 319 HIS   A C   1 
ATOM   2623 O O   . HIS   A 1 319 ? -50.26176  -15.92798 -91.75590  1.000 23.49114  ? 319 HIS   A O   1 
ATOM   2624 C CB  . HIS   A 1 319 ? -47.62689  -16.05152 -90.81396  1.000 16.76301  ? 319 HIS   A CB  1 
ATOM   2625 C CG  . HIS   A 1 319 ? -46.13293  -16.10739 -90.70681  1.000 30.61484  ? 319 HIS   A CG  1 
ATOM   2626 N ND1 . HIS   A 1 319 ? -45.46256  -17.12551 -90.05890  1.000 23.19140  ? 319 HIS   A ND1 1 
ATOM   2627 C CD2 . HIS   A 1 319 ? -45.17755  -15.26422 -91.17156  1.000 23.98489  ? 319 HIS   A CD2 1 
ATOM   2628 C CE1 . HIS   A 1 319 ? -44.16136  -16.90419 -90.12925  1.000 25.00341  ? 319 HIS   A CE1 1 
ATOM   2629 N NE2 . HIS   A 1 319 ? -43.96127  -15.77993 -90.79517  1.000 22.55263  ? 319 HIS   A NE2 1 
ATOM   2630 N N   . LYS   A 1 320 ? -50.27520  -13.68540 -91.75505  1.000 23.75193  ? 320 LYS   A N   1 
ATOM   2631 C CA  . LYS   A 1 320 ? -51.71797  -13.61764 -91.94137  1.000 26.31272  ? 320 LYS   A CA  1 
ATOM   2632 C C   . LYS   A 1 320 ? -52.05044  -13.40474 -93.41388  1.000 18.32901  ? 320 LYS   A C   1 
ATOM   2633 O O   . LYS   A 1 320 ? -51.30225  -12.71549 -94.12732  1.000 21.04760  ? 320 LYS   A O   1 
ATOM   2634 C CB  . LYS   A 1 320 ? -52.30939  -12.48130 -91.10467  1.000 23.26132  ? 320 LYS   A CB  1 
ATOM   2635 C CG  . LYS   A 1 320 ? -51.97466  -12.60551 -89.60509  1.000 30.91998  ? 320 LYS   A CG  1 
ATOM   2636 C CD  . LYS   A 1 320 ? -52.26354  -14.01854 -89.08493  1.000 37.83075  ? 320 LYS   A CD  1 
ATOM   2637 C CE  . LYS   A 1 320 ? -51.83327  -14.20374 -87.62615  1.000 49.14761  ? 320 LYS   A CE  1 
ATOM   2638 N NZ  . LYS   A 1 320 ? -51.89639  -15.64800 -87.20851  1.000 46.92744  ? 320 LYS   A NZ  1 
ATOM   2639 N N   . PRO   A 1 321 ? -53.13572  -14.00315 -93.90178  1.000 16.88903  ? 321 PRO   A N   1 
ATOM   2640 C CA  . PRO   A 1 321 ? -53.48600  -13.84958 -95.32375  1.000 21.26633  ? 321 PRO   A CA  1 
ATOM   2641 C C   . PRO   A 1 321 ? -53.72475  -12.39462 -95.68505  1.000 23.58904  ? 321 PRO   A C   1 
ATOM   2642 O O   . PRO   A 1 321 ? -54.42799  -11.66333 -94.98230  1.000 21.72452  ? 321 PRO   A O   1 
ATOM   2643 C CB  . PRO   A 1 321 ? -54.76582  -14.67705 -95.47517  1.000 16.18250  ? 321 PRO   A CB  1 
ATOM   2644 C CG  . PRO   A 1 321 ? -55.31307  -14.80199 -94.09828  1.000 22.41495  ? 321 PRO   A CG  1 
ATOM   2645 C CD  . PRO   A 1 321 ? -54.13579  -14.78989 -93.16534  1.000 15.11958  ? 321 PRO   A CD  1 
ATOM   2646 N N   . LYS   A 1 322 ? -53.10792  -11.97751 -96.77592  1.000 21.63646  ? 322 LYS   A N   1 
ATOM   2647 C CA  . LYS   A 1 322 ? -53.33342  -10.66566 -97.33606  1.000 16.76127  ? 322 LYS   A CA  1 
ATOM   2648 C C   . LYS   A 1 322 ? -54.56407  -10.70617 -98.23213  1.000 21.11259  ? 322 LYS   A C   1 
ATOM   2649 O O   . LYS   A 1 322 ? -55.07940  -11.77824 -98.56325  1.000 22.10661  ? 322 LYS   A O   1 
ATOM   2650 C CB  . LYS   A 1 322 ? -52.09292  -10.23055 -98.10692  1.000 17.01061  ? 322 LYS   A CB  1 
ATOM   2651 C CG  . LYS   A 1 322 ? -50.94177  -9.84366  -97.20819  1.000 18.99086  ? 322 LYS   A CG  1 
ATOM   2652 C CD  . LYS   A 1 322 ? -49.61826  -9.89301  -97.95158  1.000 19.89566  ? 322 LYS   A CD  1 
ATOM   2653 C CE  . LYS   A 1 322 ? -49.51450  -8.79419  -98.99893  1.000 18.18437  ? 322 LYS   A CE  1 
ATOM   2654 N NZ  . LYS   A 1 322 ? -48.25866  -8.94917  -99.80813  1.000 19.85273  ? 322 LYS   A NZ  1 
ATOM   2655 N N   . PRO   A 1 323 ? -55.08828  -9.54477  -98.62653  1.000 20.75153  ? 323 PRO   A N   1 
ATOM   2656 C CA  . PRO   A 1 323 ? -56.18485  -9.55445  -99.60795  1.000 24.05491  ? 323 PRO   A CA  1 
ATOM   2657 C C   . PRO   A 1 323 ? -55.83205  -10.28156 -100.90010 1.000 18.11308  ? 323 PRO   A C   1 
ATOM   2658 O O   . PRO   A 1 323 ? -56.71423  -10.89390 -101.51602 1.000 18.16415  ? 323 PRO   A O   1 
ATOM   2659 C CB  . PRO   A 1 323 ? -56.45437  -8.06114  -99.83905  1.000 15.84712  ? 323 PRO   A CB  1 
ATOM   2660 C CG  . PRO   A 1 323 ? -56.02131  -7.41055  -98.55341  1.000 25.76316  ? 323 PRO   A CG  1 
ATOM   2661 C CD  . PRO   A 1 323 ? -54.82317  -8.19084  -98.10255  1.000 21.67010  ? 323 PRO   A CD  1 
ATOM   2662 N N   . ALA   A 1 324 ? -54.56525  -10.25884 -101.32375 1.000 16.72809  ? 324 ALA   A N   1 
ATOM   2663 C CA  . ALA   A 1 324 ? -54.18307  -11.05619 -102.48940 1.000 18.93639  ? 324 ALA   A CA  1 
ATOM   2664 C C   . ALA   A 1 324 ? -54.45691  -12.54197 -102.26910 1.000 22.12635  ? 324 ALA   A C   1 
ATOM   2665 O O   . ALA   A 1 324 ? -54.82768  -13.24665 -103.21507 1.000 26.45222  ? 324 ALA   A O   1 
ATOM   2666 C CB  . ALA   A 1 324 ? -52.71685  -10.82300 -102.84444 1.000 17.28503  ? 324 ALA   A CB  1 
ATOM   2667 N N   . PHE   A 1 325 ? -54.33463  -13.02842 -101.02853 1.000 20.59275  ? 325 PHE   A N   1 
ATOM   2668 C CA  . PHE   A 1 325 ? -54.61226  -14.43850 -100.76184 1.000 17.04250  ? 325 PHE   A CA  1 
ATOM   2669 C C   . PHE   A 1 325 ? -56.04310  -14.79873 -101.15221 1.000 21.76648  ? 325 PHE   A C   1 
ATOM   2670 O O   . PHE   A 1 325 ? -56.29114  -15.80920 -101.82825 1.000 21.67130  ? 325 PHE   A O   1 
ATOM   2671 C CB  . PHE   A 1 325 ? -54.35074  -14.74713 -99.28591  1.000 18.00186  ? 325 PHE   A CB  1 
ATOM   2672 C CG  . PHE   A 1 325 ? -54.87589  -16.08288 -98.84712  1.000 18.64551  ? 325 PHE   A CG  1 
ATOM   2673 C CD1 . PHE   A 1 325 ? -56.17321  -16.21628 -98.38125  1.000 20.95935  ? 325 PHE   A CD1 1 
ATOM   2674 C CD2 . PHE   A 1 325 ? -54.07496  -17.20666 -98.90367  1.000 17.29145  ? 325 PHE   A CD2 1 
ATOM   2675 C CE1 . PHE   A 1 325 ? -56.66901  -17.45261 -97.98759  1.000 24.88687  ? 325 PHE   A CE1 1 
ATOM   2676 C CE2 . PHE   A 1 325 ? -54.55138  -18.44349 -98.50494  1.000 18.85363  ? 325 PHE   A CE2 1 
ATOM   2677 C CZ  . PHE   A 1 325 ? -55.85222  -18.56961 -98.04925  1.000 27.46949  ? 325 PHE   A CZ  1 
ATOM   2678 N N   . TRP   A 1 326 ? -57.00198  -13.96202 -100.75527 1.000 22.91796  ? 326 TRP   A N   1 
ATOM   2679 C CA  . TRP   A 1 326 ? -58.40871  -14.29837 -100.96382 1.000 18.19097  ? 326 TRP   A CA  1 
ATOM   2680 C C   . TRP   A 1 326 ? -58.77245  -14.29833 -102.44418 1.000 21.30683  ? 326 TRP   A C   1 
ATOM   2681 O O   . TRP   A 1 326 ? -59.49893  -15.18610 -102.90963 1.000 22.41796  ? 326 TRP   A O   1 
ATOM   2682 C CB  . TRP   A 1 326 ? -59.28077  -13.33298 -100.17030 1.000 15.44862  ? 326 TRP   A CB  1 
ATOM   2683 C CG  . TRP   A 1 326 ? -59.02632  -13.46036 -98.67777  1.000 18.88162  ? 326 TRP   A CG  1 
ATOM   2684 C CD1 . TRP   A 1 326 ? -58.29124  -12.61578 -97.89216  1.000 13.89449  ? 326 TRP   A CD1 1 
ATOM   2685 C CD2 . TRP   A 1 326 ? -59.47469  -14.51866 -97.81863  1.000 10.08803  ? 326 TRP   A CD2 1 
ATOM   2686 N NE1 . TRP   A 1 326 ? -58.27053  -13.07869 -96.59952  1.000 14.78988  ? 326 TRP   A NE1 1 
ATOM   2687 C CE2 . TRP   A 1 326 ? -58.99704  -14.24009 -96.52916  1.000 12.40498  ? 326 TRP   A CE2 1 
ATOM   2688 C CE3 . TRP   A 1 326 ? -60.24775  -15.65975 -98.01630  1.000 16.10394  ? 326 TRP   A CE3 1 
ATOM   2689 C CZ2 . TRP   A 1 326 ? -59.27733  -15.05738 -95.43774  1.000 14.30382  ? 326 TRP   A CZ2 1 
ATOM   2690 C CZ3 . TRP   A 1 326 ? -60.51277  -16.47897 -96.93650  1.000 16.64471  ? 326 TRP   A CZ3 1 
ATOM   2691 C CH2 . TRP   A 1 326 ? -60.03007  -16.17435 -95.66450  1.000 13.24479  ? 326 TRP   A CH2 1 
ATOM   2692 N N   A ARG   A 1 327 ? -58.27358  -13.32156 -103.20439 0.600 21.29677  ? 327 ARG   A N   1 
ATOM   2693 N N   B ARG   A 1 327 ? -58.27415  -13.32017 -103.20361 0.400 21.28319  ? 327 ARG   A N   1 
ATOM   2694 C CA  A ARG   A 1 327 ? -58.51800  -13.33473 -104.64357 0.600 21.00386  ? 327 ARG   A CA  1 
ATOM   2695 C CA  B ARG   A 1 327 ? -58.50634  -13.33135 -104.64475 0.400 21.01779  ? 327 ARG   A CA  1 
ATOM   2696 C C   A ARG   A 1 327 ? -57.84660  -14.53368 -105.30174 0.600 20.02407  ? 327 ARG   A C   1 
ATOM   2697 C C   B ARG   A 1 327 ? -57.84867  -14.54046 -105.29442 0.400 20.14311  ? 327 ARG   A C   1 
ATOM   2698 O O   A ARG   A 1 327 ? -58.45971  -15.20672 -106.13735 0.600 23.44643  ? 327 ARG   A O   1 
ATOM   2699 O O   B ARG   A 1 327 ? -58.46332  -15.21491 -106.12853 0.400 23.40789  ? 327 ARG   A O   1 
ATOM   2700 C CB  A ARG   A 1 327 ? -58.05322  -12.01738 -105.27758 0.600 20.81617  ? 327 ARG   A CB  1 
ATOM   2701 C CB  B ARG   A 1 327 ? -57.99399  -12.03632 -105.27890 0.400 20.84262  ? 327 ARG   A CB  1 
ATOM   2702 C CG  A ARG   A 1 327 ? -58.97665  -10.84374 -104.95530 0.600 21.43200  ? 327 ARG   A CG  1 
ATOM   2703 C CG  B ARG   A 1 327 ? -58.59216  -10.78044 -104.67775 0.400 21.11946  ? 327 ARG   A CG  1 
ATOM   2704 C CD  A ARG   A 1 327 ? -58.73540  -9.58733  -105.80424 0.600 23.45277  ? 327 ARG   A CD  1 
ATOM   2705 C CD  B ARG   A 1 327 ? -58.84905  -9.69912  -105.72135 0.400 23.34013  ? 327 ARG   A CD  1 
ATOM   2706 N NE  A ARG   A 1 327 ? -59.42997  -9.61211  -107.09108 0.600 25.17951  ? 327 ARG   A NE  1 
ATOM   2707 N NE  B ARG   A 1 327 ? -59.16029  -8.42309  -105.08056 0.400 21.79501  ? 327 ARG   A NE  1 
ATOM   2708 C CZ  A ARG   A 1 327 ? -60.00423  -8.55312  -107.66485 0.600 22.32377  ? 327 ARG   A CZ  1 
ATOM   2709 C CZ  B ARG   A 1 327 ? -59.70689  -7.37734  -105.69122 0.400 23.04708  ? 327 ARG   A CZ  1 
ATOM   2710 N NH1 A ARG   A 1 327 ? -59.98717  -7.36921  -107.06895 0.600 19.72750  ? 327 ARG   A NH1 1 
ATOM   2711 N NH1 B ARG   A 1 327 ? -60.02449  -7.43846  -106.98013 0.400 19.83474  ? 327 ARG   A NH1 1 
ATOM   2712 N NH2 A ARG   A 1 327 ? -60.60407  -8.68338  -108.84227 0.600 19.58504  ? 327 ARG   A NH2 1 
ATOM   2713 N NH2 B ARG   A 1 327 ? -59.93757  -6.26509  -105.00160 0.400 22.86771  ? 327 ARG   A NH2 1 
ATOM   2714 N N   . ALA   A 1 328 ? -56.60525  -14.84349 -104.90595 1.000 21.35131  ? 328 ALA   A N   1 
ATOM   2715 C CA  . ALA   A 1 328 ? -55.87746  -15.94958 -105.53080 1.000 20.05745  ? 328 ALA   A CA  1 
ATOM   2716 C C   . ALA   A 1 328 ? -56.60136  -17.28234 -105.35734 1.000 26.67601  ? 328 ALA   A C   1 
ATOM   2717 O O   . ALA   A 1 328 ? -56.70435  -18.06285 -106.31353 1.000 16.83144  ? 328 ALA   A O   1 
ATOM   2718 C CB  . ALA   A 1 328 ? -54.45873  -16.04504 -104.96950 1.000 11.30441  ? 328 ALA   A CB  1 
ATOM   2719 N N   . VAL   A 1 329 ? -57.10858  -17.57181 -104.14942 1.000 21.43414  ? 329 VAL   A N   1 
ATOM   2720 C CA  . VAL   A 1 329 ? -57.73631  -18.87615 -103.93189 1.000 20.91626  ? 329 VAL   A CA  1 
ATOM   2721 C C   . VAL   A 1 329 ? -59.16128  -18.94423 -104.45067 1.000 24.70020  ? 329 VAL   A C   1 
ATOM   2722 O O   . VAL   A 1 329 ? -59.79818  -20.00001 -104.36168 1.000 24.80469  ? 329 VAL   A O   1 
ATOM   2723 C CB  . VAL   A 1 329 ? -57.77922  -19.28395 -102.44731 1.000 26.55278  ? 329 VAL   A CB  1 
ATOM   2724 C CG1 . VAL   A 1 329 ? -56.37164  -19.40374 -101.89515 1.000 22.01697  ? 329 VAL   A CG1 1 
ATOM   2725 C CG2 . VAL   A 1 329 ? -58.61108  -18.29045 -101.65319 1.000 22.28988  ? 329 VAL   A CG2 1 
ATOM   2726 N N   . SER   A 1 330 ? -59.69380  -17.86124 -104.99465 1.000 25.32550  ? 330 SER   A N   1 
ATOM   2727 C CA  . SER   A 1 330 ? -61.10425  -17.84481 -105.33877 1.000 29.77774  ? 330 SER   A CA  1 
ATOM   2728 C C   . SER   A 1 330 ? -61.33760  -17.80682 -106.84331 1.000 26.81745  ? 330 SER   A C   1 
ATOM   2729 O O   . SER   A 1 330 ? -62.46828  -17.59932 -107.27465 1.000 36.09349  ? 330 SER   A O   1 
ATOM   2730 C CB  . SER   A 1 330 ? -61.77348  -16.66582 -104.62819 1.000 28.16621  ? 330 SER   A CB  1 
ATOM   2731 O OG  . SER   A 1 330 ? -61.94524  -16.97783 -103.23630 1.000 34.14528  ? 330 SER   A OG  1 
ATOM   2732 N N   . VAL   A 1 331 ? -60.29883  -18.02396 -107.64488 1.000 28.46710  ? 331 VAL   A N   1 
ATOM   2733 C CA  . VAL   A 1 331 ? -60.42940  -18.10234 -109.09093 1.000 20.45285  ? 331 VAL   A CA  1 
ATOM   2734 C C   . VAL   A 1 331 ? -60.99583  -19.44426 -109.50188 1.000 18.87291  ? 331 VAL   A C   1 
ATOM   2735 O O   . VAL   A 1 331 ? -61.38333  -19.63737 -110.65590 1.000 25.73293  ? 331 VAL   A O   1 
ATOM   2736 C CB  . VAL   A 1 331 ? -59.08119  -17.88021 -109.78935 1.000 26.94947  ? 331 VAL   A CB  1 
ATOM   2737 C CG1 . VAL   A 1 331 ? -58.50017  -16.50902 -109.43600 1.000 21.15646  ? 331 VAL   A CG1 1 
ATOM   2738 C CG2 . VAL   A 1 331 ? -58.12415  -19.00431 -109.41791 1.000 26.23811  ? 331 VAL   A CG2 1 
ATOM   2739 O OXT . VAL   A 1 331 ? -61.07286  -20.37141 -108.70624 1.000 22.37852  ? 331 VAL   A OXT 1 
ATOM   2740 N N   . SER   B 1 4   ? -62.09913  -4.02087  -112.22972 1.000 37.14709  ? 4   SER   B N   1 
ATOM   2741 C CA  . SER   B 1 4   ? -63.47004  -4.25005  -111.77966 1.000 52.15189  ? 4   SER   B CA  1 
ATOM   2742 C C   . SER   B 1 4   ? -63.62373  -5.64211  -111.13423 1.000 52.51270  ? 4   SER   B C   1 
ATOM   2743 O O   . SER   B 1 4   ? -62.87084  -6.58054  -111.43321 1.000 65.46300  ? 4   SER   B O   1 
ATOM   2744 C CB  . SER   B 1 4   ? -64.44885  -4.09767  -112.93746 1.000 50.83490  ? 4   SER   B CB  1 
ATOM   2745 O OG  . SER   B 1 4   ? -65.69316  -3.61516  -112.45906 1.000 61.16698  ? 4   SER   B OG  1 
ATOM   2746 N N   . LEU   B 1 5   ? -64.61131  -5.76324  -110.24781 1.000 38.86457  ? 5   LEU   B N   1 
ATOM   2747 C CA  . LEU   B 1 5   ? -64.90789  -7.01848  -109.58171 1.000 33.48023  ? 5   LEU   B CA  1 
ATOM   2748 C C   . LEU   B 1 5   ? -65.87002  -7.86306  -110.41748 1.000 25.42322  ? 5   LEU   B C   1 
ATOM   2749 O O   . LEU   B 1 5   ? -66.59712  -7.34211  -111.26354 1.000 26.81416  ? 5   LEU   B O   1 
ATOM   2750 C CB  . LEU   B 1 5   ? -65.53752  -6.75640  -108.21470 1.000 32.32027  ? 5   LEU   B CB  1 
ATOM   2751 C CG  . LEU   B 1 5   ? -64.72728  -6.62713  -106.91779 1.000 43.75617  ? 5   LEU   B CG  1 
ATOM   2752 C CD1 . LEU   B 1 5   ? -63.45438  -5.78026  -107.06857 1.000 41.95755  ? 5   LEU   B CD1 1 
ATOM   2753 C CD2 . LEU   B 1 5   ? -65.63472  -6.08578  -105.80406 1.000 30.54607  ? 5   LEU   B CD2 1 
ATOM   2754 N N   . PRO   B 1 6   ? -65.90087  -9.17613  -110.19505 1.000 17.95425  ? 6   PRO   B N   1 
ATOM   2755 C CA  . PRO   B 1 6   ? -67.04549  -9.96827  -110.66782 1.000 24.87351  ? 6   PRO   B CA  1 
ATOM   2756 C C   . PRO   B 1 6   ? -68.35030  -9.39309  -110.12627 1.000 26.27604  ? 6   PRO   B C   1 
ATOM   2757 O O   . PRO   B 1 6   ? -68.41589  -8.87292  -109.00883 1.000 20.52897  ? 6   PRO   B O   1 
ATOM   2758 C CB  . PRO   B 1 6   ? -66.78212  -11.36604 -110.09933 1.000 20.31445  ? 6   PRO   B CB  1 
ATOM   2759 C CG  . PRO   B 1 6   ? -65.34417  -11.38791 -109.73377 1.000 21.62908  ? 6   PRO   B CG  1 
ATOM   2760 C CD  . PRO   B 1 6   ? -64.92095  -9.97702  -109.44544 1.000 23.32623  ? 6   PRO   B CD  1 
ATOM   2761 N N   . SER   B 1 7   ? -69.39001  -9.48306  -110.93674 1.000 22.74670  ? 7   SER   B N   1 
ATOM   2762 C CA  . SER   B 1 7   ? -70.71007  -8.99005  -110.57618 1.000 27.04867  ? 7   SER   B CA  1 
ATOM   2763 C C   . SER   B 1 7   ? -71.52941  -10.14791 -110.01951 1.000 27.94901  ? 7   SER   B C   1 
ATOM   2764 O O   . SER   B 1 7   ? -71.69983  -11.17618 -110.69250 1.000 21.99377  ? 7   SER   B O   1 
ATOM   2765 C CB  . SER   B 1 7   ? -71.40089  -8.36515  -111.78513 1.000 25.22257  ? 7   SER   B CB  1 
ATOM   2766 O OG  . SER   B 1 7   ? -72.64616  -7.79893  -111.41815 1.000 33.42744  ? 7   SER   B OG  1 
ATOM   2767 N N   . LEU   B 1 8   ? -72.03175  -9.97753  -108.79249 1.000 23.87834  ? 8   LEU   B N   1 
ATOM   2768 C CA  . LEU   B 1 8   ? -72.74683  -11.06146 -108.12511 1.000 21.08091  ? 8   LEU   B CA  1 
ATOM   2769 C C   . LEU   B 1 8   ? -73.85387  -11.64221 -109.00132 1.000 19.58970  ? 8   LEU   B C   1 
ATOM   2770 O O   . LEU   B 1 8   ? -73.96366  -12.86746 -109.14763 1.000 18.08956  ? 8   LEU   B O   1 
ATOM   2771 C CB  . LEU   B 1 8   ? -73.30990  -10.56640 -106.79323 1.000 22.98695  ? 8   LEU   B CB  1 
ATOM   2772 C CG  . LEU   B 1 8   ? -72.22601  -10.45919 -105.71847 1.000 26.81167  ? 8   LEU   B CG  1 
ATOM   2773 C CD1 . LEU   B 1 8   ? -72.75177  -9.66361  -104.55326 1.000 15.00065  ? 8   LEU   B CD1 1 
ATOM   2774 C CD2 . LEU   B 1 8   ? -71.74541  -11.84398 -105.28006 1.000 13.32945  ? 8   LEU   B CD2 1 
ATOM   2775 N N   . ARG   B 1 9   ? -74.68544  -10.77840 -109.60228 1.000 18.18488  ? 9   ARG   B N   1 
ATOM   2776 C CA  . ARG   B 1 9   ? -75.77066  -11.29809 -110.43649 1.000 27.96049  ? 9   ARG   B CA  1 
ATOM   2777 C C   . ARG   B 1 9   ? -75.22761  -12.04321 -111.64800 1.000 26.95555  ? 9   ARG   B C   1 
ATOM   2778 O O   . ARG   B 1 9   ? -75.83594  -13.02785 -112.08978 1.000 17.92782  ? 9   ARG   B O   1 
ATOM   2779 C CB  . ARG   B 1 9   ? -76.71554  -10.17527 -110.88703 1.000 21.77164  ? 9   ARG   B CB  1 
ATOM   2780 C CG  . ARG   B 1 9   ? -76.00887  -8.97069  -111.50405 1.000 25.38288  ? 9   ARG   B CG  1 
ATOM   2781 C CD  . ARG   B 1 9   ? -76.98232  -7.98549  -112.13849 1.000 23.83114  ? 9   ARG   B CD  1 
ATOM   2782 N NE  . ARG   B 1 9   ? -76.29147  -7.03188  -113.00761 1.000 25.76117  ? 9   ARG   B NE  1 
ATOM   2783 C CZ  . ARG   B 1 9   ? -75.82655  -5.85568  -112.59618 1.000 26.63971  ? 9   ARG   B CZ  1 
ATOM   2784 N NH1 . ARG   B 1 9   ? -75.98965  -5.48727  -111.33591 1.000 25.13342  ? 9   ARG   B NH1 1 
ATOM   2785 N NH2 . ARG   B 1 9   ? -75.20255  -5.04359  -113.43760 1.000 25.53583  ? 9   ARG   B NH2 1 
ATOM   2786 N N   . ASP   B 1 10  ? -74.07844  -11.60195 -112.18132 1.000 16.89669  ? 10  ASP   B N   1 
ATOM   2787 C CA  . ASP   B 1 10  ? -73.46399  -12.29474 -113.31073 1.000 19.69079  ? 10  ASP   B CA  1 
ATOM   2788 C C   . ASP   B 1 10  ? -72.88223  -13.63971 -112.88363 1.000 23.73447  ? 10  ASP   B C   1 
ATOM   2789 O O   . ASP   B 1 10  ? -73.12031  -14.66272 -113.53543 1.000 28.84381  ? 10  ASP   B O   1 
ATOM   2790 C CB  . ASP   B 1 10  ? -72.39680  -11.40723 -113.94329 1.000 25.22413  ? 10  ASP   B CB  1 
ATOM   2791 C CG  . ASP   B 1 10  ? -72.99164  -10.22848 -114.69738 1.000 25.06416  ? 10  ASP   B CG  1 
ATOM   2792 O OD1 . ASP   B 1 10  ? -74.21546  -10.23120 -114.93813 1.000 28.55512  ? 10  ASP   B OD1 1 
ATOM   2793 O OD2 . ASP   B 1 10  ? -72.24234  -9.29188  -115.04497 1.000 31.41446  ? 10  ASP   B OD2 1 
ATOM   2794 N N   . VAL   B 1 11  ? -72.14602  -13.66587 -111.76900 1.000 21.78133  ? 11  VAL   B N   1 
ATOM   2795 C CA  . VAL   B 1 11  ? -71.60561  -14.92533 -111.24939 1.000 19.46450  ? 11  VAL   B CA  1 
ATOM   2796 C C   . VAL   B 1 11  ? -72.70058  -15.97903 -111.10634 1.000 28.98174  ? 11  VAL   B C   1 
ATOM   2797 O O   . VAL   B 1 11  ? -72.48783  -17.16155 -111.41281 1.000 29.37367  ? 11  VAL   B O   1 
ATOM   2798 C CB  . VAL   B 1 11  ? -70.87501  -14.68809 -109.90804 1.000 22.97531  ? 11  VAL   B CB  1 
ATOM   2799 C CG1 . VAL   B 1 11  ? -70.44436  -16.01365 -109.28792 1.000 20.93377  ? 11  VAL   B CG1 1 
ATOM   2800 C CG2 . VAL   B 1 11  ? -69.66113  -13.78678 -110.10226 1.000 19.41289  ? 11  VAL   B CG2 1 
ATOM   2801 N N   . PHE   B 1 12  ? -73.89009  -15.57791 -110.64337 1.000 22.85267  ? 12  PHE   B N   1 
ATOM   2802 C CA  . PHE   B 1 12  ? -74.95049  -16.54041 -110.36101 1.000 23.18753  ? 12  PHE   B CA  1 
ATOM   2803 C C   . PHE   B 1 12  ? -76.07301  -16.51300 -111.39566 1.000 21.31831  ? 12  PHE   B C   1 
ATOM   2804 O O   . PHE   B 1 12  ? -77.12434  -17.12808 -111.17040 1.000 24.83123  ? 12  PHE   B O   1 
ATOM   2805 C CB  . PHE   B 1 12  ? -75.48838  -16.32153 -108.93967 1.000 19.29997  ? 12  PHE   B CB  1 
ATOM   2806 C CG  . PHE   B 1 12  ? -74.46235  -16.58674 -107.86959 1.000 20.99931  ? 12  PHE   B CG  1 
ATOM   2807 C CD1 . PHE   B 1 12  ? -74.11558  -17.89129 -107.52755 1.000 18.53761  ? 12  PHE   B CD1 1 
ATOM   2808 C CD2 . PHE   B 1 12  ? -73.80508  -15.53515 -107.23838 1.000 18.96134  ? 12  PHE   B CD2 1 
ATOM   2809 C CE1 . PHE   B 1 12  ? -73.14505  -18.14100 -106.55028 1.000 21.13231  ? 12  PHE   B CE1 1 
ATOM   2810 C CE2 . PHE   B 1 12  ? -72.82205  -15.77807 -106.25292 1.000 17.99831  ? 12  PHE   B CE2 1 
ATOM   2811 C CZ  . PHE   B 1 12  ? -72.48664  -17.07354 -105.91416 1.000 14.53130  ? 12  PHE   B CZ  1 
ATOM   2812 N N   . ALA   B 1 13  ? -75.84503  -15.86524 -112.54270 1.000 17.35588  ? 13  ALA   B N   1 
ATOM   2813 C CA  . ALA   B 1 13  ? -76.80698  -15.73456 -113.63746 1.000 20.72056  ? 13  ALA   B CA  1 
ATOM   2814 C C   . ALA   B 1 13  ? -77.62217  -16.98274 -113.92638 1.000 26.21232  ? 13  ALA   B C   1 
ATOM   2815 O O   . ALA   B 1 13  ? -78.83244  -16.89045 -114.15339 1.000 36.95473  ? 13  ALA   B O   1 
ATOM   2816 C CB  . ALA   B 1 13  ? -76.09280  -15.31282 -114.91745 1.000 22.04235  ? 13  ALA   B CB  1 
ATOM   2817 N N   . ASN   B 1 14  ? -76.99829  -18.15321 -113.92167 1.000 23.77281  ? 14  ASN   B N   1 
ATOM   2818 C CA  . ASN   B 1 14  ? -77.75389  -19.36354 -114.21930 1.000 27.82398  ? 14  ASN   B CA  1 
ATOM   2819 C C   . ASN   B 1 14  ? -78.28788  -20.05707 -112.98259 1.000 34.13774  ? 14  ASN   B C   1 
ATOM   2820 O O   . ASN   B 1 14  ? -78.89163  -21.12980 -113.10052 1.000 29.58377  ? 14  ASN   B O   1 
ATOM   2821 C CB  . ASN   B 1 14  ? -76.90132  -20.33596 -115.03440 1.000 34.18197  ? 14  ASN   B CB  1 
ATOM   2822 C CG  . ASN   B 1 14  ? -76.44523  -19.72647 -116.33426 1.000 46.80600  ? 14  ASN   B CG  1 
ATOM   2823 O OD1 . ASN   B 1 14  ? -77.25876  -19.23111 -117.12388 1.000 58.55086  ? 14  ASN   B OD1 1 
ATOM   2824 N ND2 . ASN   B 1 14  ? -75.13969  -19.72197 -116.55445 1.000 48.92896  ? 14  ASN   B ND2 1 
ATOM   2825 N N   . ASP   B 1 15  ? -78.09564  -19.47502 -111.80461 1.000 31.60043  ? 15  ASP   B N   1 
ATOM   2826 C CA  . ASP   B 1 15  ? -78.50934  -20.12136 -110.57028 1.000 29.24887  ? 15  ASP   B CA  1 
ATOM   2827 C C   . ASP   B 1 15  ? -79.69393  -19.43212 -109.91566 1.000 24.87896  ? 15  ASP   B C   1 
ATOM   2828 O O   . ASP   B 1 15  ? -80.70971  -20.07613 -109.64038 1.000 21.36396  ? 15  ASP   B O   1 
ATOM   2829 C CB  . ASP   B 1 15  ? -77.30555  -20.18347 -109.62640 1.000 28.16788  ? 15  ASP   B CB  1 
ATOM   2830 C CG  . ASP   B 1 15  ? -76.09262  -20.78647 -110.31174 1.000 34.65153  ? 15  ASP   B CG  1 
ATOM   2831 O OD1 . ASP   B 1 15  ? -76.27653  -21.79922 -111.01726 1.000 45.38596  ? 15  ASP   B OD1 1 
ATOM   2832 O OD2 . ASP   B 1 15  ? -74.97301  -20.24696 -110.18492 1.000 33.31561  ? 15  ASP   B OD2 1 
ATOM   2833 N N   . PHE   B 1 16  ? -79.60333  -18.12432 -109.70295 1.000 21.96940  ? 16  PHE   B N   1 
ATOM   2834 C CA  . PHE   B 1 16  ? -80.64510  -17.37680 -109.01931 1.000 17.83065  ? 16  PHE   B CA  1 
ATOM   2835 C C   . PHE   B 1 16  ? -80.28592  -15.90383 -109.09199 1.000 17.07799  ? 16  PHE   B C   1 
ATOM   2836 O O   . PHE   B 1 16  ? -79.13272  -15.54265 -109.34028 1.000 20.08808  ? 16  PHE   B O   1 
ATOM   2837 C CB  . PHE   B 1 16  ? -80.79220  -17.82627 -107.56008 1.000 20.43091  ? 16  PHE   B CB  1 
ATOM   2838 C CG  . PHE   B 1 16  ? -79.50188  -18.27757 -106.93616 1.000 18.23144  ? 16  PHE   B CG  1 
ATOM   2839 C CD1 . PHE   B 1 16  ? -78.47104  -17.37416 -106.71419 1.000 19.00866  ? 16  PHE   B CD1 1 
ATOM   2840 C CD2 . PHE   B 1 16  ? -79.31487  -19.60707 -106.58064 1.000 19.28700  ? 16  PHE   B CD2 1 
ATOM   2841 C CE1 . PHE   B 1 16  ? -77.27842  -17.78799 -106.14440 1.000 19.41626  ? 16  PHE   B CE1 1 
ATOM   2842 C CE2 . PHE   B 1 16  ? -78.12431  -20.02953 -106.00494 1.000 20.82806  ? 16  PHE   B CE2 1 
ATOM   2843 C CZ  . PHE   B 1 16  ? -77.10860  -19.11938 -105.78506 1.000 20.31679  ? 16  PHE   B CZ  1 
ATOM   2844 N N   . ARG   B 1 17  ? -81.29031  -15.06264 -108.87919 1.000 16.87349  ? 17  ARG   B N   1 
ATOM   2845 C CA  . ARG   B 1 17  ? -81.08123  -13.62813 -108.77896 1.000 20.38739  ? 17  ARG   B CA  1 
ATOM   2846 C C   . ARG   B 1 17  ? -80.41004  -13.28387 -107.45040 1.000 23.83561  ? 17  ARG   B C   1 
ATOM   2847 O O   . ARG   B 1 17  ? -80.51725  -14.00522 -106.45102 1.000 21.20523  ? 17  ARG   B O   1 
ATOM   2848 C CB  . ARG   B 1 17  ? -82.41814  -12.88067 -108.90715 1.000 20.18819  ? 17  ARG   B CB  1 
ATOM   2849 C CG  . ARG   B 1 17  ? -82.94692  -12.76668 -110.35590 1.000 25.86326  ? 17  ARG   B CG  1 
ATOM   2850 C CD  . ARG   B 1 17  ? -84.38613  -12.19688 -110.43372 1.000 29.31029  ? 17  ARG   B CD  1 
ATOM   2851 N NE  . ARG   B 1 17  ? -85.30165  -13.01906 -109.64584 1.000 51.39409  ? 17  ARG   B NE  1 
ATOM   2852 C CZ  . ARG   B 1 17  ? -86.24447  -13.81881 -110.14435 1.000 46.97322  ? 17  ARG   B CZ  1 
ATOM   2853 N NH1 . ARG   B 1 17  ? -86.44235  -13.90658 -111.45836 1.000 42.95784  ? 17  ARG   B NH1 1 
ATOM   2854 N NH2 . ARG   B 1 17  ? -86.99767  -14.53407 -109.31348 1.000 41.80414  ? 17  ARG   B NH2 1 
ATOM   2855 N N   . ILE   B 1 18  ? -79.71505  -12.15848 -107.44414 1.000 19.21200  ? 18  ILE   B N   1 
ATOM   2856 C CA  . ILE   B 1 18  ? -79.04526  -11.65683 -106.25637 1.000 19.33518  ? 18  ILE   B CA  1 
ATOM   2857 C C   . ILE   B 1 18  ? -79.72337  -10.35133 -105.86406 1.000 24.59712  ? 18  ILE   B C   1 
ATOM   2858 O O   . ILE   B 1 18  ? -79.77195  -9.40319  -106.66369 1.000 19.35558  ? 18  ILE   B O   1 
ATOM   2859 C CB  . ILE   B 1 18  ? -77.53780  -11.45845 -106.49661 1.000 24.96647  ? 18  ILE   B CB  1 
ATOM   2860 C CG1 . ILE   B 1 18  ? -76.86623  -12.79513 -106.83340 1.000 18.81387  ? 18  ILE   B CG1 1 
ATOM   2861 C CG2 . ILE   B 1 18  ? -76.89972  -10.88028 -105.27231 1.000 14.65321  ? 18  ILE   B CG2 1 
ATOM   2862 C CD1 . ILE   B 1 18  ? -76.89452  -13.80021 -105.67213 1.000 15.55705  ? 18  ILE   B CD1 1 
ATOM   2863 N N   . GLY   B 1 19  ? -80.24097  -10.29667 -104.63275 1.000 19.26697  ? 19  GLY   B N   1 
ATOM   2864 C CA  . GLY   B 1 19  ? -80.98460  -9.12808  -104.20229 1.000 20.56044  ? 19  GLY   B CA  1 
ATOM   2865 C C   . GLY   B 1 19  ? -80.44599  -8.44017  -102.96739 1.000 19.38844  ? 19  GLY   B C   1 
ATOM   2866 O O   . GLY   B 1 19  ? -79.65785  -9.02866  -102.22006 1.000 18.86511  ? 19  GLY   B O   1 
ATOM   2867 N N   . ALA   B 1 20  ? -80.89813  -7.20359  -102.72502 1.000 18.57286  ? 20  ALA   B N   1 
ATOM   2868 C CA  . ALA   B 1 20  ? -80.57200  -6.45940  -101.51500 1.000 16.25625  ? 20  ALA   B CA  1 
ATOM   2869 C C   . ALA   B 1 20  ? -81.80466  -5.74464  -100.97032 1.000 17.40085  ? 20  ALA   B C   1 
ATOM   2870 O O   . ALA   B 1 20  ? -82.60669  -5.21112  -101.74399 1.000 11.54272  ? 20  ALA   B O   1 
ATOM   2871 C CB  . ALA   B 1 20  ? -79.47076  -5.43246  -101.78137 1.000 10.71958  ? 20  ALA   B CB  1 
ATOM   2872 N N   . ALA   B 1 21  ? -81.94007  -5.72046  -99.63383  1.000 10.48533  ? 21  ALA   B N   1 
ATOM   2873 C CA  . ALA   B 1 21  ? -82.92555  -4.85806  -98.98422  1.000 12.75687  ? 21  ALA   B CA  1 
ATOM   2874 C C   . ALA   B 1 21  ? -82.38714  -3.43656  -98.93132  1.000 16.94947  ? 21  ALA   B C   1 
ATOM   2875 O O   . ALA   B 1 21  ? -81.21672  -3.21474  -98.59825  1.000 13.25351  ? 21  ALA   B O   1 
ATOM   2876 C CB  . ALA   B 1 21  ? -83.25737  -5.34583  -97.56979  1.000 12.30602  ? 21  ALA   B CB  1 
ATOM   2877 N N   . VAL   B 1 22  ? -83.23444  -2.46957  -99.27934  1.000 14.09733  ? 22  VAL   B N   1 
ATOM   2878 C CA  . VAL   B 1 22  ? -82.81197  -1.08046  -99.40258  1.000 14.65190  ? 22  VAL   B CA  1 
ATOM   2879 C C   . VAL   B 1 22  ? -83.89464  -0.18326  -98.82330  1.000 20.89878  ? 22  VAL   B C   1 
ATOM   2880 O O   . VAL   B 1 22  ? -85.04301  -0.59441  -98.61437  1.000 19.05003  ? 22  VAL   B O   1 
ATOM   2881 C CB  . VAL   B 1 22  ? -82.54758  -0.66214  -100.87086 1.000 21.18284  ? 22  VAL   B CB  1 
ATOM   2882 C CG1 . VAL   B 1 22  ? -81.54134  -1.59760  -101.58514 1.000 9.60339   ? 22  VAL   B CG1 1 
ATOM   2883 C CG2 . VAL   B 1 22  ? -83.87183  -0.61816  -101.62629 1.000 14.98958  ? 22  VAL   B CG2 1 
ATOM   2884 N N   . ASN   B 1 23  ? -83.51362  1.05213   -98.57839  1.000 14.97569  ? 23  ASN   B N   1 
ATOM   2885 C CA  . ASN   B 1 23  ? -84.45580  2.13249   -98.33924  1.000 23.88167  ? 23  ASN   B CA  1 
ATOM   2886 C C   . ASN   B 1 23  ? -83.95506  3.30439   -99.17561  1.000 20.68493  ? 23  ASN   B C   1 
ATOM   2887 O O   . ASN   B 1 23  ? -82.84931  3.22552   -99.71298  1.000 24.40261  ? 23  ASN   B O   1 
ATOM   2888 C CB  . ASN   B 1 23  ? -84.55768  2.44758   -96.84355  1.000 21.27131  ? 23  ASN   B CB  1 
ATOM   2889 C CG  . ASN   B 1 23  ? -83.23040  2.85960   -96.23156  1.000 25.94876  ? 23  ASN   B CG  1 
ATOM   2890 O OD1 . ASN   B 1 23  ? -82.50025  3.66626   -96.80092  1.000 25.91002  ? 23  ASN   B OD1 1 
ATOM   2891 N ND2 . ASN   B 1 23  ? -82.92012  2.31815   -95.05296  1.000 21.94189  ? 23  ASN   B ND2 1 
ATOM   2892 N N   . PRO   B 1 24  ? -84.70626  4.39037   -99.34142  1.000 32.38248  ? 24  PRO   B N   1 
ATOM   2893 C CA  . PRO   B 1 24  ? -84.21129  5.44976   -100.24121 1.000 27.83867  ? 24  PRO   B CA  1 
ATOM   2894 C C   . PRO   B 1 24  ? -82.87000  6.03935   -99.81686  1.000 25.79149  ? 24  PRO   B C   1 
ATOM   2895 O O   . PRO   B 1 24  ? -82.11905  6.51454   -100.67974 1.000 34.54510  ? 24  PRO   B O   1 
ATOM   2896 C CB  . PRO   B 1 24  ? -85.34050  6.49226   -100.21274 1.000 26.73089  ? 24  PRO   B CB  1 
ATOM   2897 C CG  . PRO   B 1 24  ? -86.57769  5.66999   -99.92972  1.000 24.93167  ? 24  PRO   B CG  1 
ATOM   2898 C CD  . PRO   B 1 24  ? -86.11294  4.61548   -98.94930  1.000 32.17894  ? 24  PRO   B CD  1 
ATOM   2899 N N   . VAL   B 1 25  ? -82.52589  5.99645   -98.52640  1.000 26.11402  ? 25  VAL   B N   1 
ATOM   2900 C CA  . VAL   B 1 25  ? -81.23365  6.51968   -98.08439  1.000 21.45650  ? 25  VAL   B CA  1 
ATOM   2901 C C   . VAL   B 1 25  ? -80.09774  5.57863   -98.48191  1.000 25.03814  ? 25  VAL   B C   1 
ATOM   2902 O O   . VAL   B 1 25  ? -79.07366  6.01601   -99.02086  1.000 30.97518  ? 25  VAL   B O   1 
ATOM   2903 C CB  . VAL   B 1 25  ? -81.24773  6.77939   -96.56996  1.000 26.56189  ? 25  VAL   B CB  1 
ATOM   2904 C CG1 . VAL   B 1 25  ? -79.83693  6.97441   -96.04896  1.000 25.03680  ? 25  VAL   B CG1 1 
ATOM   2905 C CG2 . VAL   B 1 25  ? -82.09252  7.99853   -96.26351  1.000 27.37949  ? 25  VAL   B CG2 1 
ATOM   2906 N N   . THR   B 1 26  ? -80.24911  4.27418   -98.22729  1.000 21.55239  ? 26  THR   B N   1 
ATOM   2907 C CA  . THR   B 1 26  ? -79.16121  3.36633   -98.57963  1.000 23.44653  ? 26  THR   B CA  1 
ATOM   2908 C C   . THR   B 1 26  ? -79.03142  3.18724   -100.08401 1.000 23.59495  ? 26  THR   B C   1 
ATOM   2909 O O   . THR   B 1 26  ? -77.93616  2.87050   -100.56232 1.000 23.41638  ? 26  THR   B O   1 
ATOM   2910 C CB  . THR   B 1 26  ? -79.33483  2.00631   -97.91166  1.000 20.78550  ? 26  THR   B CB  1 
ATOM   2911 O OG1 . THR   B 1 26  ? -80.50835  1.37758   -98.42809  1.000 22.51069  ? 26  THR   B OG1 1 
ATOM   2912 C CG2 . THR   B 1 26  ? -79.45432  2.16260   -96.39495  1.000 20.42916  ? 26  THR   B CG2 1 
ATOM   2913 N N   . ILE   B 1 27  ? -80.11093  3.39514   -100.83953 1.000 20.26285  ? 27  ILE   B N   1 
ATOM   2914 C CA  . ILE   B 1 27  ? -79.99057  3.45493   -102.29405 1.000 22.11935  ? 27  ILE   B CA  1 
ATOM   2915 C C   . ILE   B 1 27  ? -78.95983  4.50399   -102.70241 1.000 25.18444  ? 27  ILE   B C   1 
ATOM   2916 O O   . ILE   B 1 27  ? -78.13629  4.26225   -103.58685 1.000 28.98004  ? 27  ILE   B O   1 
ATOM   2917 C CB  . ILE   B 1 27  ? -81.35815  3.73106   -102.94213 1.000 26.96383  ? 27  ILE   B CB  1 
ATOM   2918 C CG1 . ILE   B 1 27  ? -82.20147  2.45632   -102.97854 1.000 26.06999  ? 27  ILE   B CG1 1 
ATOM   2919 C CG2 . ILE   B 1 27  ? -81.17087  4.25454   -104.35441 1.000 29.24351  ? 27  ILE   B CG2 1 
ATOM   2920 C CD1 . ILE   B 1 27  ? -83.56358  2.65844   -103.60625 1.000 18.29394  ? 27  ILE   B CD1 1 
ATOM   2921 N N   . GLU   B 1 28  ? -78.97551  5.67700   -102.05970 1.000 20.07339  ? 28  GLU   B N   1 
ATOM   2922 C CA  . GLU   B 1 28  ? -77.96631  6.69034   -102.35836 1.000 26.58085  ? 28  GLU   B CA  1 
ATOM   2923 C C   . GLU   B 1 28  ? -76.60639  6.30233   -101.79077 1.000 26.90444  ? 28  GLU   B C   1 
ATOM   2924 O O   . GLU   B 1 28  ? -75.59386  6.35070   -102.49355 1.000 36.13165  ? 28  GLU   B O   1 
ATOM   2925 C CB  . GLU   B 1 28  ? -78.39782  8.05438   -101.81738 1.000 27.59289  ? 28  GLU   B CB  1 
ATOM   2926 C CG  . GLU   B 1 28  ? -79.64173  8.60989   -102.49768 1.000 40.80927  ? 28  GLU   B CG  1 
ATOM   2927 C CD  . GLU   B 1 28  ? -79.51904  8.64487   -104.01936 1.000 45.45892  ? 28  GLU   B CD  1 
ATOM   2928 O OE1 . GLU   B 1 28  ? -78.40407  8.93244   -104.51394 1.000 47.70259  ? 28  GLU   B OE1 1 
ATOM   2929 O OE2 . GLU   B 1 28  ? -80.53286  8.38058   -104.71577 1.000 42.32763  ? 28  GLU   B OE2 1 
ATOM   2930 N N   . MET   B 1 29  ? -76.56494  5.92033   -100.51746 1.000 21.99747  ? 29  MET   B N   1 
ATOM   2931 C CA  . MET   B 1 29  ? -75.30561  5.55034   -99.88142  1.000 25.67954  ? 29  MET   B CA  1 
ATOM   2932 C C   . MET   B 1 29  ? -74.61459  4.38616   -100.59032 1.000 26.90335  ? 29  MET   B C   1 
ATOM   2933 O O   . MET   B 1 29  ? -73.38054  4.33685   -100.64112 1.000 24.35806  ? 29  MET   B O   1 
ATOM   2934 C CB  . MET   B 1 29  ? -75.57415  5.19243   -98.42337  1.000 24.07684  ? 29  MET   B CB  1 
ATOM   2935 C CG  . MET   B 1 29  ? -74.44178  5.43236   -97.46048  1.000 30.49598  ? 29  MET   B CG  1 
ATOM   2936 S SD  . MET   B 1 29  ? -74.89480  4.88091   -95.78314  1.000 38.06872  ? 29  MET   B SD  1 
ATOM   2937 C CE  . MET   B 1 29  ? -75.02655  3.11874   -96.05380  1.000 31.33538  ? 29  MET   B CE  1 
ATOM   2938 N N   . GLN   B 1 30  ? -75.38252  3.43966   -101.13613 1.000 25.00743  ? 30  GLN   B N   1 
ATOM   2939 C CA  . GLN   B 1 30  ? -74.83052  2.19819   -101.66878 1.000 20.72281  ? 30  GLN   B CA  1 
ATOM   2940 C C   . GLN   B 1 30  ? -75.09218  2.04850   -103.16288 1.000 21.97202  ? 30  GLN   B C   1 
ATOM   2941 O O   . GLN   B 1 30  ? -75.05868  0.92869   -103.68743 1.000 20.22498  ? 30  GLN   B O   1 
ATOM   2942 C CB  . GLN   B 1 30  ? -75.38895  1.00202   -100.88931 1.000 16.40621  ? 30  GLN   B CB  1 
ATOM   2943 C CG  . GLN   B 1 30  ? -74.94489  1.01544   -99.40950  1.000 16.83299  ? 30  GLN   B CG  1 
ATOM   2944 C CD  . GLN   B 1 30  ? -75.65421  -0.02109  -98.55678  1.000 27.37995  ? 30  GLN   B CD  1 
ATOM   2945 O OE1 . GLN   B 1 30  ? -76.81312  -0.36847  -98.81550  1.000 23.05947  ? 30  GLN   B OE1 1 
ATOM   2946 N NE2 . GLN   B 1 30  ? -74.95687  -0.53251  -97.53264  1.000 18.20912  ? 30  GLN   B NE2 1 
ATOM   2947 N N   . LYS   B 1 31  ? -75.30302  3.16597   -103.86588 1.000 22.74754  ? 31  LYS   B N   1 
ATOM   2948 C CA  . LYS   B 1 31  ? -75.83362  3.10522   -105.22259 1.000 23.12412  ? 31  LYS   B CA  1 
ATOM   2949 C C   . LYS   B 1 31  ? -74.95420  2.26474   -106.14055 1.000 22.67500  ? 31  LYS   B C   1 
ATOM   2950 O O   . LYS   B 1 31  ? -75.45094  1.39584   -106.86697 1.000 23.87343  ? 31  LYS   B O   1 
ATOM   2951 C CB  . LYS   B 1 31  ? -75.99901  4.51411   -105.78042 1.000 17.16270  ? 31  LYS   B CB  1 
ATOM   2952 C CG  . LYS   B 1 31  ? -76.79058  4.53713   -107.06648 1.000 25.40663  ? 31  LYS   B CG  1 
ATOM   2953 C CD  . LYS   B 1 31  ? -76.98958  5.95202   -107.57414 1.000 34.21099  ? 31  LYS   B CD  1 
ATOM   2954 C CE  . LYS   B 1 31  ? -78.07938  6.66844   -106.80486 1.000 42.12174  ? 31  LYS   B CE  1 
ATOM   2955 N NZ  . LYS   B 1 31  ? -78.38914  7.98450   -107.43133 1.000 48.99132  ? 31  LYS   B NZ  1 
ATOM   2956 N N   . GLN   B 1 32  ? -73.64292  2.50828   -106.13012 1.000 22.89071  ? 32  GLN   B N   1 
ATOM   2957 C CA  . GLN   B 1 32  ? -72.79193  1.84876   -107.11580 1.000 25.19652  ? 32  GLN   B CA  1 
ATOM   2958 C C   . GLN   B 1 32  ? -72.71250  0.34308   -106.86902 1.000 23.02874  ? 32  GLN   B C   1 
ATOM   2959 O O   . GLN   B 1 32  ? -72.76137  -0.44940  -107.82200 1.000 18.32642  ? 32  GLN   B O   1 
ATOM   2960 C CB  . GLN   B 1 32  ? -71.39870  2.47714   -107.12531 1.000 25.02926  ? 32  GLN   B CB  1 
ATOM   2961 C CG  . GLN   B 1 32  ? -70.60099  2.07824   -108.35129 1.000 21.25132  ? 32  GLN   B CG  1 
ATOM   2962 C CD  . GLN   B 1 32  ? -71.31850  2.44297   -109.63065 1.000 29.81556  ? 32  GLN   B CD  1 
ATOM   2963 O OE1 . GLN   B 1 32  ? -71.65716  3.60225   -109.83305 1.000 35.76844  ? 32  GLN   B OE1 1 
ATOM   2964 N NE2 . GLN   B 1 32  ? -71.55656  1.45536   -110.50346 1.000 21.84205  ? 32  GLN   B NE2 1 
ATOM   2965 N N   . LEU   B 1 33  ? -72.60218  -0.07080  -105.60063 1.000 18.72388  ? 33  LEU   B N   1 
ATOM   2966 C CA  . LEU   B 1 33  ? -72.63014  -1.49695  -105.28350 1.000 17.01408  ? 33  LEU   B CA  1 
ATOM   2967 C C   . LEU   B 1 33  ? -73.89023  -2.15297  -105.83688 1.000 19.84291  ? 33  LEU   B C   1 
ATOM   2968 O O   . LEU   B 1 33  ? -73.83591  -3.23119  -106.44156 1.000 17.10960  ? 33  LEU   B O   1 
ATOM   2969 C CB  . LEU   B 1 33  ? -72.55450  -1.70851  -103.77172 1.000 17.58122  ? 33  LEU   B CB  1 
ATOM   2970 C CG  . LEU   B 1 33  ? -71.24518  -1.82390  -103.00606 1.000 25.12620  ? 33  LEU   B CG  1 
ATOM   2971 C CD1 . LEU   B 1 33  ? -71.63155  -2.20760  -101.59212 1.000 20.22843  ? 33  LEU   B CD1 1 
ATOM   2972 C CD2 . LEU   B 1 33  ? -70.23068  -2.83164  -103.60823 1.000 13.80621  ? 33  LEU   B CD2 1 
ATOM   2973 N N   . LEU   B 1 34  ? -75.04195  -1.51088  -105.63518 1.000 22.11697  ? 34  LEU   B N   1 
ATOM   2974 C CA  . LEU   B 1 34  ? -76.29508  -2.08679  -106.10556 1.000 17.49002  ? 34  LEU   B CA  1 
ATOM   2975 C C   . LEU   B 1 34  ? -76.30521  -2.17313  -107.61708 1.000 17.71272  ? 34  LEU   B C   1 
ATOM   2976 O O   . LEU   B 1 34  ? -76.59512  -3.23156  -108.19429 1.000 20.89839  ? 34  LEU   B O   1 
ATOM   2977 C CB  . LEU   B 1 34  ? -77.47946  -1.25289  -105.61073 1.000 18.08068  ? 34  LEU   B CB  1 
ATOM   2978 C CG  . LEU   B 1 34  ? -77.63973  -1.17697  -104.09403 1.000 15.64248  ? 34  LEU   B CG  1 
ATOM   2979 C CD1 . LEU   B 1 34  ? -78.47182  0.03451   -103.73368 1.000 16.84366  ? 34  LEU   B CD1 1 
ATOM   2980 C CD2 . LEU   B 1 34  ? -78.25518  -2.47348  -103.53813 1.000 9.17832   ? 34  LEU   B CD2 1 
ATOM   2981 N N   . ILE   B 1 35  ? -75.98640  -1.06048  -108.27711 1.000 18.68116  ? 35  ILE   B N   1 
ATOM   2982 C CA  . ILE   B 1 35  ? -75.92062  -1.06137  -109.73457 1.000 21.78659  ? 35  ILE   B CA  1 
ATOM   2983 C C   . ILE   B 1 35  ? -74.98264  -2.15900  -110.21922 1.000 25.00360  ? 35  ILE   B C   1 
ATOM   2984 O O   . ILE   B 1 35  ? -75.30421  -2.90311  -111.15556 1.000 23.26184  ? 35  ILE   B O   1 
ATOM   2985 C CB  . ILE   B 1 35  ? -75.49210  0.32590   -110.24625 1.000 25.89097  ? 35  ILE   B CB  1 
ATOM   2986 C CG1 . ILE   B 1 35  ? -76.60166  1.33821   -109.97265 1.000 21.34502  ? 35  ILE   B CG1 1 
ATOM   2987 C CG2 . ILE   B 1 35  ? -75.17109  0.26720   -111.73281 1.000 20.78750  ? 35  ILE   B CG2 1 
ATOM   2988 C CD1 . ILE   B 1 35  ? -76.26166  2.75754   -110.38519 1.000 22.80816  ? 35  ILE   B CD1 1 
ATOM   2989 N N   . ASP   B 1 36  ? -73.83534  -2.32277  -109.54448 1.000 20.20929  ? 36  ASP   B N   1 
ATOM   2990 C CA  . ASP   B 1 36  ? -72.84069  -3.27907  -110.01215 1.000 19.55111  ? 36  ASP   B CA  1 
ATOM   2991 C C   . ASP   B 1 36  ? -73.21654  -4.72976  -109.72253 1.000 21.18418  ? 36  ASP   B C   1 
ATOM   2992 O O   . ASP   B 1 36  ? -72.81967  -5.61208  -110.48627 1.000 24.03130  ? 36  ASP   B O   1 
ATOM   2993 C CB  . ASP   B 1 36  ? -71.47714  -2.96288  -109.39894 1.000 23.10638  ? 36  ASP   B CB  1 
ATOM   2994 C CG  . ASP   B 1 36  ? -70.86578  -1.67289  -109.94322 1.000 23.36117  ? 36  ASP   B CG  1 
ATOM   2995 O OD1 . ASP   B 1 36  ? -71.34477  -1.16684  -110.98436 1.000 24.92061  ? 36  ASP   B OD1 1 
ATOM   2996 O OD2 . ASP   B 1 36  ? -69.91296  -1.15432  -109.31329 1.000 27.74098  ? 36  ASP   B OD2 1 
ATOM   2997 N N   . HIS   B 1 37  ? -73.98980  -5.02197  -108.66791 1.000 16.82983  ? 37  HIS   B N   1 
ATOM   2998 C CA  . HIS   B 1 37  ? -74.08255  -6.41662  -108.23766 1.000 15.58546  ? 37  HIS   B CA  1 
ATOM   2999 C C   . HIS   B 1 37  ? -75.47085  -7.05829  -108.24811 1.000 22.07121  ? 37  HIS   B C   1 
ATOM   3000 O O   . HIS   B 1 37  ? -75.55716  -8.25523  -108.53117 1.000 22.01026  ? 37  HIS   B O   1 
ATOM   3001 C CB  . HIS   B 1 37  ? -73.48550  -6.55776  -106.84119 1.000 14.88487  ? 37  HIS   B CB  1 
ATOM   3002 C CG  . HIS   B 1 37  ? -72.00136  -6.40986  -106.82832 1.000 20.42273  ? 37  HIS   B CG  1 
ATOM   3003 N ND1 . HIS   B 1 37  ? -71.15932  -7.35955  -107.37164 1.000 16.87432  ? 37  HIS   B ND1 1 
ATOM   3004 C CD2 . HIS   B 1 37  ? -71.20728  -5.40568  -106.38147 1.000 17.78142  ? 37  HIS   B CD2 1 
ATOM   3005 C CE1 . HIS   B 1 37  ? -69.90744  -6.95930  -107.22603 1.000 20.06060  ? 37  HIS   B CE1 1 
ATOM   3006 N NE2 . HIS   B 1 37  ? -69.90802  -5.77693  -106.63239 1.000 18.07807  ? 37  HIS   B NE2 1 
ATOM   3007 N N   . VAL   B 1 38  ? -76.55498  -6.33568  -107.95054 1.000 18.18401  ? 38  VAL   B N   1 
ATOM   3008 C CA  . VAL   B 1 38  ? -77.84156  -7.00048  -107.73731 1.000 19.91682  ? 38  VAL   B CA  1 
ATOM   3009 C C   . VAL   B 1 38  ? -78.72059  -6.89464  -108.98241 1.000 18.36020  ? 38  VAL   B C   1 
ATOM   3010 O O   . VAL   B 1 38  ? -78.57826  -5.98148  -109.80754 1.000 21.12264  ? 38  VAL   B O   1 
ATOM   3011 C CB  . VAL   B 1 38  ? -78.54686  -6.42992  -106.48229 1.000 18.20319  ? 38  VAL   B CB  1 
ATOM   3012 C CG1 . VAL   B 1 38  ? -77.56449  -6.37023  -105.31994 1.000 11.78860  ? 38  VAL   B CG1 1 
ATOM   3013 C CG2 . VAL   B 1 38  ? -79.12987  -5.03485  -106.74268 1.000 14.74439  ? 38  VAL   B CG2 1 
ATOM   3014 N N   . ASN   B 1 39  ? -79.62805  -7.86384  -109.13699 1.000 16.17165  ? 39  ASN   B N   1 
ATOM   3015 C CA  . ASN   B 1 39  ? -80.72292  -7.74254  -110.09910 1.000 28.90128  ? 39  ASN   B CA  1 
ATOM   3016 C C   . ASN   B 1 39  ? -82.08635  -7.93840  -109.43191 1.000 25.75329  ? 39  ASN   B C   1 
ATOM   3017 O O   . ASN   B 1 39  ? -83.06194  -8.31929  -110.10219 1.000 25.08173  ? 39  ASN   B O   1 
ATOM   3018 C CB  . ASN   B 1 39  ? -80.55178  -8.71196  -111.27682 1.000 15.93050  ? 39  ASN   B CB  1 
ATOM   3019 C CG  . ASN   B 1 39  ? -80.33295  -10.14378 -110.83046 1.000 23.76412  ? 39  ASN   B CG  1 
ATOM   3020 O OD1 . ASN   B 1 39  ? -80.42211  -10.46655 -109.63637 1.000 16.54481  ? 39  ASN   B OD1 1 
ATOM   3021 N ND2 . ASN   B 1 39  ? -79.99469  -11.00717 -111.78693 1.000 21.16061  ? 39  ASN   B ND2 1 
ATOM   3022 N N   . SER   B 1 40  ? -82.17455  -7.67620  -108.12943 1.000 17.76894  ? 40  SER   B N   1 
ATOM   3023 C CA  . SER   B 1 40  ? -83.43445  -7.71961  -107.40928 1.000 13.42400  ? 40  SER   B CA  1 
ATOM   3024 C C   . SER   B 1 40  ? -83.30927  -6.79824  -106.20979 1.000 20.13761  ? 40  SER   B C   1 
ATOM   3025 O O   . SER   B 1 40  ? -82.21135  -6.58722  -105.68157 1.000 25.16241  ? 40  SER   B O   1 
ATOM   3026 C CB  . SER   B 1 40  ? -83.77420  -9.14620  -106.98189 1.000 17.32661  ? 40  SER   B CB  1 
ATOM   3027 O OG  . SER   B 1 40  ? -85.01069  -9.21477  -106.29745 1.000 16.79307  ? 40  SER   B OG  1 
ATOM   3028 N N   . ILE   B 1 41  ? -84.43600  -6.24593  -105.78826 1.000 18.18257  ? 41  ILE   B N   1 
ATOM   3029 C CA  . ILE   B 1 41  ? -84.47294  -5.22585  -104.74988 1.000 14.31719  ? 41  ILE   B CA  1 
ATOM   3030 C C   . ILE   B 1 41  ? -85.67542  -5.52315  -103.86646 1.000 19.28497  ? 41  ILE   B C   1 
ATOM   3031 O O   . ILE   B 1 41  ? -86.73208  -5.91979  -104.36352 1.000 19.36788  ? 41  ILE   B O   1 
ATOM   3032 C CB  . ILE   B 1 41  ? -84.55206  -3.80991  -105.37842 1.000 20.27742  ? 41  ILE   B CB  1 
ATOM   3033 C CG1 . ILE   B 1 41  ? -83.20118  -3.41015  -105.96643 1.000 22.94172  ? 41  ILE   B CG1 1 
ATOM   3034 C CG2 . ILE   B 1 41  ? -84.99698  -2.74859  -104.37911 1.000 16.05972  ? 41  ILE   B CG2 1 
ATOM   3035 C CD1 . ILE   B 1 41  ? -82.17506  -3.04887  -104.93455 1.000 14.41482  ? 41  ILE   B CD1 1 
ATOM   3036 N N   . THR   B 1 42  ? -85.50779  -5.36809  -102.55526 1.000 18.69389  ? 42  THR   B N   1 
ATOM   3037 C CA  . THR   B 1 42  ? -86.60581  -5.42484  -101.59892 1.000 8.27683   ? 42  THR   B CA  1 
ATOM   3038 C C   . THR   B 1 42  ? -86.56402  -4.15336  -100.76460 1.000 14.43273  ? 42  THR   B C   1 
ATOM   3039 O O   . THR   B 1 42  ? -85.48176  -3.63333  -100.47239 1.000 16.55152  ? 42  THR   B O   1 
ATOM   3040 C CB  . THR   B 1 42  ? -86.51695  -6.66489  -100.67726 1.000 15.12399  ? 42  THR   B CB  1 
ATOM   3041 O OG1 . THR   B 1 42  ? -86.44240  -7.86726  -101.46168 1.000 13.43795  ? 42  THR   B OG1 1 
ATOM   3042 C CG2 . THR   B 1 42  ? -87.72530  -6.74778  -99.71690  1.000 9.11237   ? 42  THR   B CG2 1 
ATOM   3043 N N   . ALA   B 1 43  ? -87.73739  -3.63008  -100.40622 1.000 15.82397  ? 43  ALA   B N   1 
ATOM   3044 C CA  . ALA   B 1 43  ? -87.80291  -2.48606  -99.50357  1.000 14.83253  ? 43  ALA   B CA  1 
ATOM   3045 C C   . ALA   B 1 43  ? -87.62979  -2.98842  -98.07059  1.000 15.83045  ? 43  ALA   B C   1 
ATOM   3046 O O   . ALA   B 1 43  ? -88.40394  -3.83477  -97.60692  1.000 16.60803  ? 43  ALA   B O   1 
ATOM   3047 C CB  . ALA   B 1 43  ? -89.12331  -1.73582  -99.67340  1.000 10.54154  ? 43  ALA   B CB  1 
ATOM   3048 N N   . GLU   B 1 44  ? -86.59950  -2.49476  -97.37878  1.000 12.86702  ? 44  GLU   B N   1 
ATOM   3049 C CA  . GLU   B 1 44  ? -86.32893  -2.99173  -96.03531  1.000 12.25206  ? 44  GLU   B CA  1 
ATOM   3050 C C   . GLU   B 1 44  ? -87.48380  -2.66770  -95.09244  1.000 12.66330  ? 44  GLU   B C   1 
ATOM   3051 O O   . GLU   B 1 44  ? -87.79825  -3.45666  -94.19882  1.000 15.71680  ? 44  GLU   B O   1 
ATOM   3052 C CB  . GLU   B 1 44  ? -85.00380  -2.41574  -95.49546  1.000 11.25240  ? 44  GLU   B CB  1 
ATOM   3053 C CG  . GLU   B 1 44  ? -84.64493  -2.98410  -94.10152  1.000 11.02945  ? 44  GLU   B CG  1 
ATOM   3054 C CD  . GLU   B 1 44  ? -83.34039  -2.45435  -93.48428  1.000 14.94166  ? 44  GLU   B CD  1 
ATOM   3055 O OE1 . GLU   B 1 44  ? -82.69137  -1.52551  -94.02924  1.000 9.77930   ? 44  GLU   B OE1 1 
ATOM   3056 O OE2 . GLU   B 1 44  ? -82.97252  -2.97674  -92.40848  1.000 15.87779  ? 44  GLU   B OE2 1 
ATOM   3057 N N   . ASN   B 1 45  ? -88.12794  -1.51318  -95.27352  1.000 8.89400   ? 45  ASN   B N   1 
ATOM   3058 C CA  . ASN   B 1 45  ? -89.26616  -1.16423  -94.43208  1.000 18.19462  ? 45  ASN   B CA  1 
ATOM   3059 C C   . ASN   B 1 45  ? -90.42467  -0.48760  -95.15578  1.000 18.41140  ? 45  ASN   B C   1 
ATOM   3060 O O   . ASN   B 1 45  ? -91.54816  -0.56530  -94.65473  1.000 17.80031  ? 45  ASN   B O   1 
ATOM   3061 C CB  . ASN   B 1 45  ? -88.81656  -0.25687  -93.27825  1.000 13.96935  ? 45  ASN   B CB  1 
ATOM   3062 C CG  . ASN   B 1 45  ? -87.99924  -0.99657  -92.24952  1.000 17.63026  ? 45  ASN   B CG  1 
ATOM   3063 O OD1 . ASN   B 1 45  ? -88.53576  -1.78989  -91.47953  1.000 17.02422  ? 45  ASN   B OD1 1 
ATOM   3064 N ND2 . ASN   B 1 45  ? -86.68269  -0.75198  -92.23614  1.000 17.26442  ? 45  ASN   B ND2 1 
ATOM   3065 N N   . HIS   B 1 46  ? -90.22804  0.14166   -96.31005  1.000 12.36201  ? 46  HIS   B N   1 
ATOM   3066 C CA  . HIS   B 1 46  ? -91.17660  1.12854   -96.78604  1.000 12.54600  ? 46  HIS   B CA  1 
ATOM   3067 C C   . HIS   B 1 46  ? -92.32185  0.54065   -97.60688  1.000 17.46588  ? 46  HIS   B C   1 
ATOM   3068 O O   . HIS   B 1 46  ? -93.16069  1.29776   -98.11212  1.000 17.61877  ? 46  HIS   B O   1 
ATOM   3069 C CB  . HIS   B 1 46  ? -90.43596  2.21553   -97.55877  1.000 15.53072  ? 46  HIS   B CB  1 
ATOM   3070 C CG  . HIS   B 1 46  ? -89.64938  3.12675   -96.66780  1.000 19.19025  ? 46  HIS   B CG  1 
ATOM   3071 N ND1 . HIS   B 1 46  ? -88.28861  2.99518   -96.47497  1.000 20.40372  ? 46  HIS   B ND1 1 
ATOM   3072 C CD2 . HIS   B 1 46  ? -90.04540  4.14896   -95.87162  1.000 19.95350  ? 46  HIS   B CD2 1 
ATOM   3073 C CE1 . HIS   B 1 46  ? -87.87894  3.91613   -95.61963  1.000 27.71131  ? 46  HIS   B CE1 1 
ATOM   3074 N NE2 . HIS   B 1 46  ? -88.92584  4.62779   -95.23709  1.000 20.79188  ? 46  HIS   B NE2 1 
ATOM   3075 N N   . MET   B 1 47  ? -92.42228  -0.77942  -97.70410  1.000 13.10071  ? 47  MET   B N   1 
ATOM   3076 C CA  . MET   B 1 47  ? -93.65885  -1.39349  -98.16474  1.000 15.94417  ? 47  MET   B CA  1 
ATOM   3077 C C   . MET   B 1 47  ? -94.35927  -2.17386  -97.06408  1.000 15.45804  ? 47  MET   B C   1 
ATOM   3078 O O   . MET   B 1 47  ? -95.25354  -2.97226  -97.35561  1.000 12.94622  ? 47  MET   B O   1 
ATOM   3079 C CB  . MET   B 1 47  ? -93.39907  -2.28108  -99.37779  1.000 14.19319  ? 47  MET   B CB  1 
ATOM   3080 C CG  . MET   B 1 47  ? -92.91406  -1.47175  -100.56963 1.000 13.44915  ? 47  MET   B CG  1 
ATOM   3081 S SD  . MET   B 1 47  ? -92.74573  -2.45313  -102.07058 1.000 17.13892  ? 47  MET   B SD  1 
ATOM   3082 C CE  . MET   B 1 47  ? -91.78599  -1.31233  -103.03464 1.000 14.36158  ? 47  MET   B CE  1 
ATOM   3083 N N   . LYS   B 1 48  ? -93.97155  -1.97043  -95.80706  1.000 12.07949  ? 48  LYS   B N   1 
ATOM   3084 C CA  . LYS   B 1 48  ? -94.74655  -2.54358  -94.72215  1.000 17.26019  ? 48  LYS   B CA  1 
ATOM   3085 C C   . LYS   B 1 48  ? -96.00026  -1.69541  -94.46809  1.000 18.53071  ? 48  LYS   B C   1 
ATOM   3086 O O   . LYS   B 1 48  ? -96.10778  -0.54664  -94.91120  1.000 16.82296  ? 48  LYS   B O   1 
ATOM   3087 C CB  . LYS   B 1 48  ? -93.88865  -2.66300  -93.46500  1.000 13.72574  ? 48  LYS   B CB  1 
ATOM   3088 C CG  . LYS   B 1 48  ? -92.80548  -3.71477  -93.58352  1.000 12.93276  ? 48  LYS   B CG  1 
ATOM   3089 C CD  . LYS   B 1 48  ? -91.64454  -3.46081  -92.63720  1.000 12.63476  ? 48  LYS   B CD  1 
ATOM   3090 C CE  . LYS   B 1 48  ? -90.60930  -4.57618  -92.76764  1.000 15.18379  ? 48  LYS   B CE  1 
ATOM   3091 N NZ  . LYS   B 1 48  ? -89.39229  -4.40916  -91.90963  1.000 11.29614  ? 48  LYS   B NZ  1 
ATOM   3092 N N   . PHE   B 1 49  ? -96.95844  -2.27941  -93.74622  1.000 13.20655  ? 49  PHE   B N   1 
ATOM   3093 C CA  . PHE   B 1 49  ? -98.26344  -1.64413  -93.61198  1.000 16.22423  ? 49  PHE   B CA  1 
ATOM   3094 C C   . PHE   B 1 49  ? -98.13765  -0.24420  -93.01365  1.000 15.99242  ? 49  PHE   B C   1 
ATOM   3095 O O   . PHE   B 1 49  ? -98.70654  0.72203   -93.53688  1.000 19.29182  ? 49  PHE   B O   1 
ATOM   3096 C CB  . PHE   B 1 49  ? -99.17897  -2.53841  -92.77618  1.000 15.70695  ? 49  PHE   B CB  1 
ATOM   3097 C CG  . PHE   B 1 49  ? -100.66659 -2.27341  -92.96940  1.000 15.08747  ? 49  PHE   B CG  1 
ATOM   3098 C CD1 . PHE   B 1 49  ? -101.21680 -1.04103  -92.64954  1.000 15.96241  ? 49  PHE   B CD1 1 
ATOM   3099 C CD2 . PHE   B 1 49  ? -101.51759 -3.28656  -93.41109  1.000 11.91786  ? 49  PHE   B CD2 1 
ATOM   3100 C CE1 . PHE   B 1 49  ? -102.57405 -0.80948  -92.78946  1.000 17.81609  ? 49  PHE   B CE1 1 
ATOM   3101 C CE2 . PHE   B 1 49  ? -102.87833 -3.07276  -93.53585  1.000 15.75441  ? 49  PHE   B CE2 1 
ATOM   3102 C CZ  . PHE   B 1 49  ? -103.41597 -1.82575  -93.23604  1.000 13.53438  ? 49  PHE   B CZ  1 
ATOM   3103 N N   . GLU   B 1 50  ? -97.35796  -0.10451  -91.94200  1.000 14.39677  ? 50  GLU   B N   1 
ATOM   3104 C CA  . GLU   B 1 50  ? -97.23998  1.18908   -91.28663  1.000 14.52695  ? 50  GLU   B CA  1 
ATOM   3105 C C   . GLU   B 1 50  ? -96.61667  2.25159   -92.18535  1.000 15.26434  ? 50  GLU   B C   1 
ATOM   3106 O O   . GLU   B 1 50  ? -96.79387  3.44872   -91.92122  1.000 16.72952  ? 50  GLU   B O   1 
ATOM   3107 C CB  . GLU   B 1 50  ? -96.42751  1.04830   -90.00192  1.000 18.94478  ? 50  GLU   B CB  1 
ATOM   3108 C CG  . GLU   B 1 50  ? -94.92620  0.91444   -90.24339  1.000 22.88494  ? 50  GLU   B CG  1 
ATOM   3109 C CD  . GLU   B 1 50  ? -94.12128  0.66173   -88.97515  1.000 22.07105  ? 50  GLU   B CD  1 
ATOM   3110 O OE1 . GLU   B 1 50  ? -94.73709  0.37371   -87.91972  1.000 19.05394  ? 50  GLU   B OE1 1 
ATOM   3111 O OE2 . GLU   B 1 50  ? -92.86516  0.73470   -89.04887  1.000 24.91532  ? 50  GLU   B OE2 1 
ATOM   3112 N N   . HIS   B 1 51  ? -95.89487  1.85699   -93.23340  1.000 12.55288  ? 51  HIS   B N   1 
ATOM   3113 C CA  . HIS   B 1 51  ? -95.25853  2.82272   -94.11779  1.000 16.90292  ? 51  HIS   B CA  1 
ATOM   3114 C C   . HIS   B 1 51  ? -96.03048  3.02555   -95.41012  1.000 18.51470  ? 51  HIS   B C   1 
ATOM   3115 O O   . HIS   B 1 51  ? -95.69895  3.92937   -96.18765  1.000 17.65970  ? 51  HIS   B O   1 
ATOM   3116 C CB  . HIS   B 1 51  ? -93.81767  2.40090   -94.43229  1.000 16.76767  ? 51  HIS   B CB  1 
ATOM   3117 C CG  . HIS   B 1 51  ? -92.88220  2.55419   -93.27261  1.000 24.94608  ? 51  HIS   B CG  1 
ATOM   3118 N ND1 . HIS   B 1 51  ? -92.45433  3.78534   -92.81744  1.000 25.21012  ? 51  HIS   B ND1 1 
ATOM   3119 C CD2 . HIS   B 1 51  ? -92.29624  1.63206   -92.46970  1.000 22.85774  ? 51  HIS   B CD2 1 
ATOM   3120 C CE1 . HIS   B 1 51  ? -91.64868  3.61457   -91.78272  1.000 18.65227  ? 51  HIS   B CE1 1 
ATOM   3121 N NE2 . HIS   B 1 51  ? -91.53737  2.31839   -91.54934  1.000 26.07336  ? 51  HIS   B NE2 1 
ATOM   3122 N N   . LEU   B 1 52  ? -97.05210  2.21759   -95.64894  1.000 17.28141  ? 52  LEU   B N   1 
ATOM   3123 C CA  . LEU   B 1 52  ? -97.92552  2.39795   -96.79368  1.000 17.65355  ? 52  LEU   B CA  1 
ATOM   3124 C C   . LEU   B 1 52  ? -99.25750  3.03110   -96.42119  1.000 21.93120  ? 52  LEU   B C   1 
ATOM   3125 O O   . LEU   B 1 52  ? -99.71858  3.92966   -97.12361  1.000 15.62313  ? 52  LEU   B O   1 
ATOM   3126 C CB  . LEU   B 1 52  ? -98.15363  1.05168   -97.48538  1.000 15.78761  ? 52  LEU   B CB  1 
ATOM   3127 C CG  . LEU   B 1 52  ? -96.87333  0.59561   -98.20139  1.000 18.22843  ? 52  LEU   B CG  1 
ATOM   3128 C CD1 . LEU   B 1 52  ? -97.09745  -0.68889  -99.00018  1.000 14.34391  ? 52  LEU   B CD1 1 
ATOM   3129 C CD2 . LEU   B 1 52  ? -96.33466  1.71471   -99.09148  1.000 14.25070  ? 52  LEU   B CD2 1 
ATOM   3130 N N   . GLN   B 1 53  ? -99.88641  2.60306   -95.32486  1.000 22.29002  ? 53  GLN   B N   1 
ATOM   3131 C CA  . GLN   B 1 53  ? -101.19142 3.12497   -94.92084  1.000 18.48534  ? 53  GLN   B CA  1 
ATOM   3132 C C   . GLN   B 1 53  ? -101.14854 3.48250   -93.43872  1.000 20.72481  ? 53  GLN   B C   1 
ATOM   3133 O O   . GLN   B 1 53  ? -101.74008 2.78870   -92.59797  1.000 18.39867  ? 53  GLN   B O   1 
ATOM   3134 C CB  . GLN   B 1 53  ? -102.31853 2.13286   -95.22736  1.000 14.31254  ? 53  GLN   B CB  1 
ATOM   3135 C CG  . GLN   B 1 53  ? -103.59947 2.86362   -95.64153  1.000 15.35607  ? 53  GLN   B CG  1 
ATOM   3136 C CD  . GLN   B 1 53  ? -104.89057 2.03509   -95.58260  1.000 16.93356  ? 53  GLN   B CD  1 
ATOM   3137 O OE1 . GLN   B 1 53  ? -105.96358 2.59929   -95.39358  1.000 22.29854  ? 53  GLN   B OE1 1 
ATOM   3138 N NE2 . GLN   B 1 53  ? -104.79922 0.72200   -95.77401  1.000 9.99519   ? 53  GLN   B NE2 1 
ATOM   3139 N N   . PRO   B 1 54  ? -100.45477 4.57617   -93.08719  1.000 20.05859  ? 54  PRO   B N   1 
ATOM   3140 C CA  . PRO   B 1 54  ? -100.31486 4.94748   -91.66187  1.000 19.80540  ? 54  PRO   B CA  1 
ATOM   3141 C C   . PRO   B 1 54  ? -101.63403 5.30302   -90.97685  1.000 21.18845  ? 54  PRO   B C   1 
ATOM   3142 O O   . PRO   B 1 54  ? -101.78272 5.05211   -89.77241  1.000 15.29799  ? 54  PRO   B O   1 
ATOM   3143 C CB  . PRO   B 1 54  ? -99.36884  6.15787   -91.70998  1.000 13.12278  ? 54  PRO   B CB  1 
ATOM   3144 C CG  . PRO   B 1 54  ? -99.51678  6.70300   -93.09928  1.000 12.69824  ? 54  PRO   B CG  1 
ATOM   3145 C CD  . PRO   B 1 54  ? -99.76287  5.51946   -93.98105  1.000 14.15803  ? 54  PRO   B CD  1 
ATOM   3146 N N   . GLU   B 1 55  ? -102.57284 5.92059   -91.69874  1.000 19.69271  ? 55  GLU   B N   1 
ATOM   3147 C CA  . GLU   B 1 55  ? -103.94976 6.08518   -91.25079  1.000 18.95296  ? 55  GLU   B CA  1 
ATOM   3148 C C   . GLU   B 1 55  ? -104.86125 5.51337   -92.31745  1.000 19.37460  ? 55  GLU   B C   1 
ATOM   3149 O O   . GLU   B 1 55  ? -104.51151 5.50075   -93.50292  1.000 20.48742  ? 55  GLU   B O   1 
ATOM   3150 C CB  . GLU   B 1 55  ? -104.32092 7.55234   -91.01123  1.000 20.58697  ? 55  GLU   B CB  1 
ATOM   3151 C CG  . GLU   B 1 55  ? -103.31155 8.29531   -90.14064  1.000 26.15151  ? 55  GLU   B CG  1 
ATOM   3152 C CD  . GLU   B 1 55  ? -103.50173 9.80372   -90.15142  1.000 29.84335  ? 55  GLU   B CD  1 
ATOM   3153 O OE1 . GLU   B 1 55  ? -104.61995 10.27568  -90.48204  1.000 39.14159  ? 55  GLU   B OE1 1 
ATOM   3154 O OE2 . GLU   B 1 55  ? -102.52286 10.51518  -89.83350  1.000 32.20470  ? 55  GLU   B OE2 1 
ATOM   3155 N N   . GLU   B 1 56  ? -106.03574 5.05101   -91.89082  1.000 19.90591  ? 56  GLU   B N   1 
ATOM   3156 C CA  . GLU   B 1 56  ? -107.00229 4.49558   -92.82879  1.000 20.40255  ? 56  GLU   B CA  1 
ATOM   3157 C C   . GLU   B 1 56  ? -107.34003 5.51514   -93.90841  1.000 19.35648  ? 56  GLU   B C   1 
ATOM   3158 O O   . GLU   B 1 56  ? -107.75903 6.63874   -93.61079  1.000 17.58358  ? 56  GLU   B O   1 
ATOM   3159 C CB  . GLU   B 1 56  ? -108.26602 4.05918   -92.09954  1.000 20.33892  ? 56  GLU   B CB  1 
ATOM   3160 C CG  . GLU   B 1 56  ? -109.24402 3.32582   -93.01034  1.000 22.51411  ? 56  GLU   B CG  1 
ATOM   3161 C CD  . GLU   B 1 56  ? -110.39183 2.67522   -92.25073  1.000 28.81936  ? 56  GLU   B CD  1 
ATOM   3162 O OE1 . GLU   B 1 56  ? -110.68948 3.11370   -91.11798  1.000 33.64025  ? 56  GLU   B OE1 1 
ATOM   3163 O OE2 . GLU   B 1 56  ? -110.98772 1.71583   -92.78604  1.000 26.86615  ? 56  GLU   B OE2 1 
ATOM   3164 N N   . GLY   B 1 57  ? -107.13664 5.12654   -95.16255  1.000 17.36105  ? 57  GLY   B N   1 
ATOM   3165 C CA  . GLY   B 1 57  ? -107.37555 6.01058   -96.28252  1.000 14.58048  ? 57  GLY   B CA  1 
ATOM   3166 C C   . GLY   B 1 57  ? -106.25059 6.96998   -96.59313  1.000 18.81903  ? 57  GLY   B C   1 
ATOM   3167 O O   . GLY   B 1 57  ? -106.35390 7.72536   -97.56742  1.000 24.97054  ? 57  GLY   B O   1 
ATOM   3168 N N   . LYS   B 1 58  ? -105.19391 6.99144   -95.79285  1.000 17.99615  ? 58  LYS   B N   1 
ATOM   3169 C CA  . LYS   B 1 58  ? -104.01911 7.79650   -96.08631  1.000 18.36719  ? 58  LYS   B CA  1 
ATOM   3170 C C   . LYS   B 1 58  ? -102.92878 6.85156   -96.58083  1.000 20.86771  ? 58  LYS   B C   1 
ATOM   3171 O O   . LYS   B 1 58  ? -102.38514 6.05771   -95.80332  1.000 20.73007  ? 58  LYS   B O   1 
ATOM   3172 C CB  . LYS   B 1 58  ? -103.57157 8.57988   -94.85280  1.000 19.89237  ? 58  LYS   B CB  1 
ATOM   3173 C CG  . LYS   B 1 58  ? -102.44687 9.54388   -95.14539  1.000 21.58046  ? 58  LYS   B CG  1 
ATOM   3174 C CD  . LYS   B 1 58  ? -101.95922 10.23123  -93.89363  1.000 30.96565  ? 58  LYS   B CD  1 
ATOM   3175 C CE  . LYS   B 1 58  ? -100.82894 11.18229  -94.24426  1.000 26.21047  ? 58  LYS   B CE  1 
ATOM   3176 N NZ  . LYS   B 1 58  ? -100.22730 11.82010  -93.05578  1.000 20.82144  ? 58  LYS   B NZ  1 
ATOM   3177 N N   . PHE   B 1 59  ? -102.62959 6.90704   -97.87196  1.000 18.47400  ? 59  PHE   B N   1 
ATOM   3178 C CA  . PHE   B 1 59  ? -101.58976 6.06113   -98.44424  1.000 17.05688  ? 59  PHE   B CA  1 
ATOM   3179 C C   . PHE   B 1 59  ? -100.34951 6.90131   -98.70387  1.000 22.35069  ? 59  PHE   B C   1 
ATOM   3180 O O   . PHE   B 1 59  ? -100.45331 8.02406   -99.21520  1.000 24.07247  ? 59  PHE   B O   1 
ATOM   3181 C CB  . PHE   B 1 59  ? -102.07163 5.37618   -99.71701  1.000 14.01089  ? 59  PHE   B CB  1 
ATOM   3182 C CG  . PHE   B 1 59  ? -103.12606 4.34266   -99.46184  1.000 18.70856  ? 59  PHE   B CG  1 
ATOM   3183 C CD1 . PHE   B 1 59  ? -104.47443 4.70177   -99.41754  1.000 13.22710  ? 59  PHE   B CD1 1 
ATOM   3184 C CD2 . PHE   B 1 59  ? -102.77772 3.01906   -99.22910  1.000 14.94886  ? 59  PHE   B CD2 1 
ATOM   3185 C CE1 . PHE   B 1 59  ? -105.45601 3.75473   -99.16395  1.000 14.09799  ? 59  PHE   B CE1 1 
ATOM   3186 C CE2 . PHE   B 1 59  ? -103.76112 2.05881   -98.97073  1.000 16.52203  ? 59  PHE   B CE2 1 
ATOM   3187 C CZ  . PHE   B 1 59  ? -105.10470 2.43073   -98.94174  1.000 17.44963  ? 59  PHE   B CZ  1 
ATOM   3188 N N   . THR   B 1 60  ? -99.18645  6.37094   -98.31138  1.000 16.78864  ? 60  THR   B N   1 
ATOM   3189 C CA  . THR   B 1 60  ? -97.90342  7.07342   -98.40131  1.000 19.58572  ? 60  THR   B CA  1 
ATOM   3190 C C   . THR   B 1 60  ? -96.93351  6.22226   -99.22147  1.000 20.32584  ? 60  THR   B C   1 
ATOM   3191 O O   . THR   B 1 60  ? -96.06142  5.54158   -98.67015  1.000 17.52591  ? 60  THR   B O   1 
ATOM   3192 C CB  . THR   B 1 60  ? -97.34757  7.37846   -96.99357  1.000 19.78975  ? 60  THR   B CB  1 
ATOM   3193 O OG1 . THR   B 1 60  ? -97.22989  6.15966   -96.24086  1.000 17.81070  ? 60  THR   B OG1 1 
ATOM   3194 C CG2 . THR   B 1 60  ? -98.27248  8.33950   -96.25629  1.000 15.97327  ? 60  THR   B CG2 1 
ATOM   3195 N N   . PHE   B 1 61  ? -97.07826  6.28517   -100.54604 1.000 15.59514  ? 61  PHE   B N   1 
ATOM   3196 C CA  . PHE   B 1 61  ? -96.28902  5.48672   -101.47665 1.000 17.93191  ? 61  PHE   B CA  1 
ATOM   3197 C C   . PHE   B 1 61  ? -94.97789  6.14624   -101.89600 1.000 20.65556  ? 61  PHE   B C   1 
ATOM   3198 O O   . PHE   B 1 61  ? -94.22419  5.54023   -102.66530 1.000 18.59741  ? 61  PHE   B O   1 
ATOM   3199 C CB  . PHE   B 1 61  ? -97.10230  5.18563   -102.74281 1.000 18.26105  ? 61  PHE   B CB  1 
ATOM   3200 C CG  . PHE   B 1 61  ? -98.23073  4.21526   -102.53422 1.000 16.33756  ? 61  PHE   B CG  1 
ATOM   3201 C CD1 . PHE   B 1 61  ? -97.97763  2.86213   -102.34600 1.000 16.78162  ? 61  PHE   B CD1 1 
ATOM   3202 C CD2 . PHE   B 1 61  ? -99.55555  4.65174   -102.55218 1.000 18.06861  ? 61  PHE   B CD2 1 
ATOM   3203 C CE1 . PHE   B 1 61  ? -99.02679  1.94713   -102.15322 1.000 19.35967  ? 61  PHE   B CE1 1 
ATOM   3204 C CE2 . PHE   B 1 61  ? -100.61331 3.74953   -102.36863 1.000 16.17307  ? 61  PHE   B CE2 1 
ATOM   3205 C CZ  . PHE   B 1 61  ? -100.35443 2.39684   -102.16971 1.000 15.49144  ? 61  PHE   B CZ  1 
ATOM   3206 N N   . GLN   B 1 62  ? -94.69256  7.36603   -101.43165 1.000 16.74191  ? 62  GLN   B N   1 
ATOM   3207 C CA  . GLN   B 1 62  ? -93.55776  8.11943   -101.96350 1.000 17.01396  ? 62  GLN   B CA  1 
ATOM   3208 C C   . GLN   B 1 62  ? -92.26340  7.32899   -101.84948 1.000 23.24574  ? 62  GLN   B C   1 
ATOM   3209 O O   . GLN   B 1 62  ? -91.54606  7.15784   -102.83988 1.000 25.62036  ? 62  GLN   B O   1 
ATOM   3210 C CB  . GLN   B 1 62  ? -93.42070  9.46356   -101.24123 1.000 24.01058  ? 62  GLN   B CB  1 
ATOM   3211 C CG  . GLN   B 1 62  ? -94.67889  10.33119  -101.28033 1.000 30.65907  ? 62  GLN   B CG  1 
ATOM   3212 C CD  . GLN   B 1 62  ? -95.46928  10.25097  -99.99844  1.000 25.18240  ? 62  GLN   B CD  1 
ATOM   3213 O OE1 . GLN   B 1 62  ? -95.89955  9.17175   -99.59957  1.000 23.99800  ? 62  GLN   B OE1 1 
ATOM   3214 N NE2 . GLN   B 1 62  ? -95.65510  11.39165  -99.33396  1.000 26.75157  ? 62  GLN   B NE2 1 
ATOM   3215 N N   . GLU   B 1 63  ? -91.95021  6.83568   -100.64498 1.000 20.29400  ? 63  GLU   B N   1 
ATOM   3216 C CA  . GLU   B 1 63  ? -90.70552  6.09511   -100.44364 1.000 24.07252  ? 63  GLU   B CA  1 
ATOM   3217 C C   . GLU   B 1 63  ? -90.69496  4.79045   -101.23975 1.000 20.04335  ? 63  GLU   B C   1 
ATOM   3218 O O   . GLU   B 1 63  ? -89.70244  4.46722   -101.90230 1.000 22.72471  ? 63  GLU   B O   1 
ATOM   3219 C CB  . GLU   B 1 63  ? -90.48409  5.82527   -98.95184  1.000 22.85884  ? 63  GLU   B CB  1 
ATOM   3220 C CG  . GLU   B 1 63  ? -90.54477  7.07346   -98.06967  1.000 26.85712  ? 63  GLU   B CG  1 
ATOM   3221 C CD  . GLU   B 1 63  ? -89.22296  7.84026   -98.03542  1.000 51.63681  ? 63  GLU   B CD  1 
ATOM   3222 O OE1 . GLU   B 1 63  ? -88.80246  8.37033   -99.09030  1.000 47.90939  ? 63  GLU   B OE1 1 
ATOM   3223 O OE2 . GLU   B 1 63  ? -88.59480  7.91031   -96.95223  1.000 57.85681  ? 63  GLU   B OE2 1 
ATOM   3224 N N   . ALA   B 1 64  ? -91.78913  4.02345   -101.19669 1.000 14.47824  ? 64  ALA   B N   1 
ATOM   3225 C CA  . ALA   B 1 64  ? -91.82324  2.79488   -101.98735 1.000 20.97071  ? 64  ALA   B CA  1 
ATOM   3226 C C   . ALA   B 1 64  ? -91.68957  3.08520   -103.48474 1.000 19.60844  ? 64  ALA   B C   1 
ATOM   3227 O O   . ALA   B 1 64  ? -91.00843  2.33937   -104.20210 1.000 18.01756  ? 64  ALA   B O   1 
ATOM   3228 C CB  . ALA   B 1 64  ? -93.09303  1.99706   -101.70214 1.000 13.28641  ? 64  ALA   B CB  1 
ATOM   3229 N N   . ASP   B 1 65  ? -92.32428  4.16438   -103.97318 1.000 16.04208  ? 65  ASP   B N   1 
ATOM   3230 C CA  . ASP   B 1 65  ? -92.16996  4.56221   -105.37791 1.000 19.31505  ? 65  ASP   B CA  1 
ATOM   3231 C C   . ASP   B 1 65  ? -90.70295  4.81330   -105.72931 1.000 25.64867  ? 65  ASP   B C   1 
ATOM   3232 O O   . ASP   B 1 65  ? -90.22925  4.37334   -106.78346 1.000 20.99842  ? 65  ASP   B O   1 
ATOM   3233 C CB  . ASP   B 1 65  ? -92.96707  5.83431   -105.68124 1.000 17.07601  ? 65  ASP   B CB  1 
ATOM   3234 C CG  . ASP   B 1 65  ? -94.48568  5.62890   -105.69956 1.000 25.34689  ? 65  ASP   B CG  1 
ATOM   3235 O OD1 . ASP   B 1 65  ? -95.02114  4.48368   -105.74304 1.000 20.25757  ? 65  ASP   B OD1 1 
ATOM   3236 O OD2 . ASP   B 1 65  ? -95.15410  6.68045   -105.66333 1.000 23.18059  ? 65  ASP   B OD2 1 
ATOM   3237 N N   . ARG   B 1 66  ? -89.97520  5.54019   -104.86275 1.000 18.10077  ? 66  ARG   B N   1 
ATOM   3238 C CA  . ARG   B 1 66  ? -88.55611  5.80537   -105.09176 1.000 21.71280  ? 66  ARG   B CA  1 
ATOM   3239 C C   . ARG   B 1 66  ? -87.75890  4.51473   -105.18555 1.000 25.59027  ? 66  ARG   B C   1 
ATOM   3240 O O   . ARG   B 1 66  ? -86.79957  4.43222   -105.95941 1.000 25.09620  ? 66  ARG   B O   1 
ATOM   3241 C CB  . ARG   B 1 66  ? -87.99150  6.69968   -103.97696 1.000 20.48302  ? 66  ARG   B CB  1 
ATOM   3242 C CG  . ARG   B 1 66  ? -88.46466  8.15598   -104.08022 1.000 34.71681  ? 66  ARG   B CG  1 
ATOM   3243 C CD  . ARG   B 1 66  ? -88.18732  9.02927   -102.84348 1.000 38.14111  ? 66  ARG   B CD  1 
ATOM   3244 N NE  . ARG   B 1 66  ? -88.92024  10.30273  -102.93641 1.000 52.46762  ? 66  ARG   B NE  1 
ATOM   3245 C CZ  . ARG   B 1 66  ? -89.70243  10.82870  -101.98419 1.000 53.33389  ? 66  ARG   B CZ  1 
ATOM   3246 N NH1 . ARG   B 1 66  ? -89.86149  10.22149  -100.81236 1.000 41.57343  ? 66  ARG   B NH1 1 
ATOM   3247 N NH2 . ARG   B 1 66  ? -90.32610  11.98458  -102.19922 1.000 45.14653  ? 66  ARG   B NH2 1 
ATOM   3248 N N   . ILE   B 1 67  ? -88.15339  3.49529   -104.42260 1.000 20.19557  ? 67  ILE   B N   1 
ATOM   3249 C CA  . ILE   B 1 67  ? -87.45448  2.21711   -104.45853 1.000 22.00751  ? 67  ILE   B CA  1 
ATOM   3250 C C   . ILE   B 1 67  ? -87.76813  1.47857   -105.75207 1.000 20.32685  ? 67  ILE   B C   1 
ATOM   3251 O O   . ILE   B 1 67  ? -86.87646  0.92519   -106.40087 1.000 27.15271  ? 67  ILE   B O   1 
ATOM   3252 C CB  . ILE   B 1 67  ? -87.82431  1.38906   -103.21448 1.000 17.67461  ? 67  ILE   B CB  1 
ATOM   3253 C CG1 . ILE   B 1 67  ? -87.27262  2.05985   -101.95341 1.000 14.19191  ? 67  ILE   B CG1 1 
ATOM   3254 C CG2 . ILE   B 1 67  ? -87.34862  -0.04995  -103.34321 1.000 12.82055  ? 67  ILE   B CG2 1 
ATOM   3255 C CD1 . ILE   B 1 67  ? -87.87974  1.52462   -100.65074 1.000 14.50637  ? 67  ILE   B CD1 1 
ATOM   3256 N N   . VAL   B 1 68  ? -89.03298  1.47656   -106.15559 1.000 16.68310  ? 68  VAL   B N   1 
ATOM   3257 C CA  . VAL   B 1 68  ? -89.43620  0.81763   -107.39325 1.000 17.18418  ? 68  VAL   B CA  1 
ATOM   3258 C C   . VAL   B 1 68  ? -88.88007  1.55526   -108.60884 1.000 21.88773  ? 68  VAL   B C   1 
ATOM   3259 O O   . VAL   B 1 68  ? -88.43898  0.92548   -109.57931 1.000 22.75626  ? 68  VAL   B O   1 
ATOM   3260 C CB  . VAL   B 1 68  ? -90.97146  0.70616   -107.43889 1.000 13.33043  ? 68  VAL   B CB  1 
ATOM   3261 C CG1 . VAL   B 1 68  ? -91.44491  0.19194   -108.79564 1.000 9.54603   ? 68  VAL   B CG1 1 
ATOM   3262 C CG2 . VAL   B 1 68  ? -91.45730  -0.18643  -106.31118 1.000 8.64270   ? 68  VAL   B CG2 1 
ATOM   3263 N N   . ASP   B 1 69  ? -88.90327  2.89570   -108.58583 1.000 18.50528  ? 69  ASP   B N   1 
ATOM   3264 C CA  . ASP   B 1 69  ? -88.34958  3.65052   -109.70632 1.000 22.91399  ? 69  ASP   B CA  1 
ATOM   3265 C C   . ASP   B 1 69  ? -86.87701  3.33114   -109.89876 1.000 23.27112  ? 69  ASP   B C   1 
ATOM   3266 O O   . ASP   B 1 69  ? -86.41316  3.17498   -111.03519 1.000 21.42007  ? 69  ASP   B O   1 
ATOM   3267 C CB  . ASP   B 1 69  ? -88.51783  5.15806   -109.50322 1.000 31.20344  ? 69  ASP   B CB  1 
ATOM   3268 C CG  . ASP   B 1 69  ? -89.97519  5.61709   -109.56055 1.000 44.09179  ? 69  ASP   B CG  1 
ATOM   3269 O OD1 . ASP   B 1 69  ? -90.82747  4.89281   -110.13835 1.000 42.01007  ? 69  ASP   B OD1 1 
ATOM   3270 O OD2 . ASP   B 1 69  ? -90.25482  6.72222   -109.03758 1.000 46.61377  ? 69  ASP   B OD2 1 
ATOM   3271 N N   . PHE   B 1 70  ? -86.12667  3.24325   -108.79181 1.000 25.06030  ? 70  PHE   B N   1 
ATOM   3272 C CA  . PHE   B 1 70  ? -84.70868  2.90800   -108.86182 1.000 21.39328  ? 70  PHE   B CA  1 
ATOM   3273 C C   . PHE   B 1 70  ? -84.49755  1.53652   -109.48809 1.000 21.47057  ? 70  PHE   B C   1 
ATOM   3274 O O   . PHE   B 1 70  ? -83.67646  1.37500   -110.39471 1.000 22.67787  ? 70  PHE   B O   1 
ATOM   3275 C CB  . PHE   B 1 70  ? -84.08554  2.94938   -107.47268 1.000 19.94187  ? 70  PHE   B CB  1 
ATOM   3276 C CG  . PHE   B 1 70  ? -82.70900  2.39667   -107.43434 1.000 20.75156  ? 70  PHE   B CG  1 
ATOM   3277 C CD1 . PHE   B 1 70  ? -81.63319  3.16545   -107.85445 1.000 21.96336  ? 70  PHE   B CD1 1 
ATOM   3278 C CD2 . PHE   B 1 70  ? -82.48099  1.09907   -107.00034 1.000 21.07757  ? 70  PHE   B CD2 1 
ATOM   3279 C CE1 . PHE   B 1 70  ? -80.34648  2.65613   -107.83304 1.000 21.64785  ? 70  PHE   B CE1 1 
ATOM   3280 C CE2 . PHE   B 1 70  ? -81.20282  0.57561   -106.97860 1.000 19.37165  ? 70  PHE   B CE2 1 
ATOM   3281 C CZ  . PHE   B 1 70  ? -80.13006  1.35600   -107.39586 1.000 21.80657  ? 70  PHE   B CZ  1 
ATOM   3282 N N   . ALA   B 1 71  ? -85.24537  0.53872   -109.02368 1.000 22.20805  ? 71  ALA   B N   1 
ATOM   3283 C CA  . ALA   B 1 71  ? -85.05411  -0.81648  -109.51253 1.000 21.69700  ? 71  ALA   B CA  1 
ATOM   3284 C C   . ALA   B 1 71  ? -85.38446  -0.90810  -110.99035 1.000 27.60103  ? 71  ALA   B C   1 
ATOM   3285 O O   . ALA   B 1 71  ? -84.58984  -1.42746  -111.78502 1.000 28.12596  ? 71  ALA   B O   1 
ATOM   3286 C CB  . ALA   B 1 71  ? -85.92394  -1.78473  -108.71153 1.000 17.83056  ? 71  ALA   B CB  1 
ATOM   3287 N N   . CYS   B 1 72  ? -86.56997  -0.41533  -111.37132 1.000 24.89929  ? 72  CYS   B N   1 
ATOM   3288 C CA  . CYS   B 1 72  ? -87.02393  -0.51512  -112.75588 1.000 28.69447  ? 72  CYS   B CA  1 
ATOM   3289 C C   . CYS   B 1 72  ? -86.08963  0.21174   -113.70946 1.000 27.86605  ? 72  CYS   B C   1 
ATOM   3290 O O   . CYS   B 1 72  ? -85.89080  -0.23551  -114.84139 1.000 33.00867  ? 72  CYS   B O   1 
ATOM   3291 C CB  . CYS   B 1 72  ? -88.45687  0.03221   -112.88406 1.000 24.86575  ? 72  CYS   B CB  1 
ATOM   3292 S SG  . CYS   B 1 72  ? -89.72765  -1.16132  -112.34434 1.000 31.60880  ? 72  CYS   B SG  1 
ATOM   3293 N N   . SER   B 1 73  ? -85.50516  1.31871   -113.27345 1.000 22.25570  ? 73  SER   B N   1 
ATOM   3294 C CA  . SER   B 1 73  ? -84.56648  2.04122   -114.11445 1.000 24.31338  ? 73  SER   B CA  1 
ATOM   3295 C C   . SER   B 1 73  ? -83.19424  1.37656   -114.19458 1.000 31.63114  ? 73  SER   B C   1 
ATOM   3296 O O   . SER   B 1 73  ? -82.34959  1.85528   -114.95358 1.000 31.85693  ? 73  SER   B O   1 
ATOM   3297 C CB  . SER   B 1 73  ? -84.41033  3.48442   -113.62288 1.000 18.61019  ? 73  SER   B CB  1 
ATOM   3298 O OG  . SER   B 1 73  ? -83.56609  3.55119   -112.48545 1.000 39.26257  ? 73  SER   B OG  1 
ATOM   3299 N N   . HIS   B 1 74  ? -82.94345  0.29508   -113.44785 1.000 26.44001  ? 74  HIS   B N   1 
ATOM   3300 C CA  . HIS   B 1 74  ? -81.70690  -0.47411  -113.58440 1.000 26.29096  ? 74  HIS   B CA  1 
ATOM   3301 C C   . HIS   B 1 74  ? -81.98183  -1.94758  -113.86756 1.000 29.28605  ? 74  HIS   B C   1 
ATOM   3302 O O   . HIS   B 1 74  ? -81.18193  -2.80158  -113.51252 1.000 27.59186  ? 74  HIS   B O   1 
ATOM   3303 C CB  . HIS   B 1 74  ? -80.82197  -0.33283  -112.34458 1.000 19.49703  ? 74  HIS   B CB  1 
ATOM   3304 C CG  . HIS   B 1 74  ? -80.32586  1.05698   -112.11814 1.000 20.72837  ? 74  HIS   B CG  1 
ATOM   3305 N ND1 . HIS   B 1 74  ? -81.05023  2.00086   -111.42216 1.000 31.52670  ? 74  HIS   B ND1 1 
ATOM   3306 C CD2 . HIS   B 1 74  ? -79.18109  1.66565   -112.49719 1.000 27.01899  ? 74  HIS   B CD2 1 
ATOM   3307 C CE1 . HIS   B 1 74  ? -80.36960  3.13272   -111.37884 1.000 24.92652  ? 74  HIS   B CE1 1 
ATOM   3308 N NE2 . HIS   B 1 74  ? -79.22935  2.95421   -112.01826 1.000 28.45622  ? 74  HIS   B NE2 1 
ATOM   3309 N N   . ARG   B 1 75  ? -83.09273  -2.23904  -114.54119 1.000 36.24642  ? 75  ARG   B N   1 
ATOM   3310 C CA  . ARG   B 1 75  ? -83.64244  -3.59026  -114.73560 1.000 43.28879  ? 75  ARG   B CA  1 
ATOM   3311 C C   . ARG   B 1 75  ? -83.33707  -4.51603  -113.55663 1.000 31.96226  ? 75  ARG   B C   1 
ATOM   3312 O O   . ARG   B 1 75  ? -82.70728  -5.56698  -113.69586 1.000 35.54083  ? 75  ARG   B O   1 
ATOM   3313 C CB  . ARG   B 1 75  ? -83.17448  -4.21413  -116.06043 1.000 49.84927  ? 75  ARG   B CB  1 
ATOM   3314 C CG  . ARG   B 1 75  ? -84.18200  -3.99239  -117.22513 1.000 72.66109  ? 75  ARG   B CG  1 
ATOM   3315 C CD  . ARG   B 1 75  ? -83.84311  -4.73565  -118.52496 1.000 83.08726  ? 75  ARG   B CD  1 
ATOM   3316 N NE  . ARG   B 1 75  ? -82.68293  -4.18490  -119.21965 1.000 82.16894  ? 75  ARG   B NE  1 
ATOM   3317 C CZ  . ARG   B 1 75  ? -82.44094  -4.27946  -120.51938 1.000 76.07001  ? 75  ARG   B CZ  1 
ATOM   3318 N NH1 . ARG   B 1 75  ? -83.23888  -4.96388  -121.32869 1.000 69.10064  ? 75  ARG   B NH1 1 
ATOM   3319 N NH2 . ARG   B 1 75  ? -81.34430  -3.71838  -121.00352 1.000 66.40704  ? 75  ARG   B NH2 1 
ATOM   3320 N N   . MET   B 1 76  ? -83.75793  -4.08785  -112.37062 1.000 26.35959  ? 76  MET   B N   1 
ATOM   3321 C CA  . MET   B 1 76  ? -83.80616  -4.94914  -111.19742 1.000 22.46640  ? 76  MET   B CA  1 
ATOM   3322 C C   . MET   B 1 76  ? -85.25075  -5.36388  -110.93907 1.000 18.74606  ? 76  MET   B C   1 
ATOM   3323 O O   . MET   B 1 76  ? -86.16297  -4.55086  -111.06660 1.000 23.87009  ? 76  MET   B O   1 
ATOM   3324 C CB  . MET   B 1 76  ? -83.23868  -4.22450  -109.97794 1.000 23.68936  ? 76  MET   B CB  1 
ATOM   3325 C CG  . MET   B 1 76  ? -81.79243  -3.76205  -110.14562 1.000 24.33922  ? 76  MET   B CG  1 
ATOM   3326 S SD  . MET   B 1 76  ? -81.33129  -2.46772  -108.98224 1.000 22.61162  ? 76  MET   B SD  1 
ATOM   3327 C CE  . MET   B 1 76  ? -79.56305  -2.33928  -109.29748 1.000 18.99629  ? 76  MET   B CE  1 
ATOM   3328 N N   . ALA   B 1 77  ? -85.45999  -6.62508  -110.58824 1.000 16.52838  ? 77  ALA   B N   1 
ATOM   3329 C CA  . ALA   B 1 77  ? -86.77452  -7.03430  -110.14165 1.000 16.58660  ? 77  ALA   B CA  1 
ATOM   3330 C C   . ALA   B 1 77  ? -87.01245  -6.55092  -108.71227 1.000 21.75840  ? 77  ALA   B C   1 
ATOM   3331 O O   . ALA   B 1 77  ? -86.09039  -6.09572  -108.02123 1.000 22.35929  ? 77  ALA   B O   1 
ATOM   3332 C CB  . ALA   B 1 77  ? -86.91642  -8.54633  -110.22134 1.000 17.15585  ? 77  ALA   B CB  1 
ATOM   3333 N N   . VAL   B 1 78  ? -88.26997  -6.64473  -108.26435 1.000 14.05946  ? 78  VAL   B N   1 
ATOM   3334 C CA  . VAL   B 1 78  ? -88.65536  -6.16204  -106.94240 1.000 16.15703  ? 78  VAL   B CA  1 
ATOM   3335 C C   . VAL   B 1 78  ? -89.50097  -7.21367  -106.24244 1.000 21.64805  ? 78  VAL   B C   1 
ATOM   3336 O O   . VAL   B 1 78  ? -90.51127  -7.67662  -106.79021 1.000 16.87838  ? 78  VAL   B O   1 
ATOM   3337 C CB  . VAL   B 1 78  ? -89.42204  -4.83058  -107.01700 1.000 13.52737  ? 78  VAL   B CB  1 
ATOM   3338 C CG1 . VAL   B 1 78  ? -89.81999  -4.34511  -105.60779 1.000 10.81011  ? 78  VAL   B CG1 1 
ATOM   3339 C CG2 . VAL   B 1 78  ? -88.59653  -3.79369  -107.71789 1.000 12.19121  ? 78  VAL   B CG2 1 
ATOM   3340 N N   . ARG   B 1 79  ? -89.09388  -7.57759  -105.02542 1.000 19.84239  ? 79  ARG   B N   1 
ATOM   3341 C CA  . ARG   B 1 79  ? -89.93073  -8.36568  -104.12823 1.000 14.13195  ? 79  ARG   B CA  1 
ATOM   3342 C C   . ARG   B 1 79  ? -90.73648  -7.42034  -103.23889 1.000 20.39791  ? 79  ARG   B C   1 
ATOM   3343 O O   . ARG   B 1 79  ? -90.17399  -6.50091  -102.62330 1.000 16.19226  ? 79  ARG   B O   1 
ATOM   3344 C CB  . ARG   B 1 79  ? -89.07993  -9.30000  -103.26893 1.000 11.42481  ? 79  ARG   B CB  1 
ATOM   3345 C CG  . ARG   B 1 79  ? -88.12594  -10.23421 -104.01929 1.000 14.21429  ? 79  ARG   B CG  1 
ATOM   3346 C CD  . ARG   B 1 79  ? -87.52668  -11.30711 -103.06093 1.000 11.68369  ? 79  ARG   B CD  1 
ATOM   3347 N NE  . ARG   B 1 79  ? -88.48462  -12.37273 -102.73022 1.000 18.06018  ? 79  ARG   B NE  1 
ATOM   3348 C CZ  . ARG   B 1 79  ? -89.27460  -12.39547 -101.64860 1.000 18.46713  ? 79  ARG   B CZ  1 
ATOM   3349 N NH1 . ARG   B 1 79  ? -89.22276  -11.41556 -100.75101 1.000 13.68814  ? 79  ARG   B NH1 1 
ATOM   3350 N NH2 . ARG   B 1 79  ? -90.11782  -13.41038 -101.45631 1.000 16.12403  ? 79  ARG   B NH2 1 
ATOM   3351 N N   . GLY   B 1 80  ? -92.04895  -7.64166  -103.16898 1.000 16.68707  ? 80  GLY   B N   1 
ATOM   3352 C CA  . GLY   B 1 80  ? -92.89044  -6.85513  -102.27301 1.000 11.32868  ? 80  GLY   B CA  1 
ATOM   3353 C C   . GLY   B 1 80  ? -92.84977  -7.39778  -100.84735 1.000 15.94565  ? 80  GLY   B C   1 
ATOM   3354 O O   . GLY   B 1 80  ? -93.07291  -8.59164  -100.61735 1.000 16.14328  ? 80  GLY   B O   1 
ATOM   3355 N N   . HIS   B 1 81  ? -92.58946  -6.51246  -99.88215  1.000 14.18502  ? 81  HIS   B N   1 
ATOM   3356 C CA  . HIS   B 1 81  ? -92.46732  -6.91859  -98.48170  1.000 13.15252  ? 81  HIS   B CA  1 
ATOM   3357 C C   . HIS   B 1 81  ? -93.00594  -5.81216  -97.57996  1.000 12.75354  ? 81  HIS   B C   1 
ATOM   3358 O O   . HIS   B 1 81  ? -92.42418  -4.72326  -97.54079  1.000 14.49823  ? 81  HIS   B O   1 
ATOM   3359 C CB  . HIS   B 1 81  ? -90.99708  -7.22096  -98.14848  1.000 11.43773  ? 81  HIS   B CB  1 
ATOM   3360 C CG  . HIS   B 1 81  ? -90.77324  -7.64655  -96.73108  1.000 11.45890  ? 81  HIS   B CG  1 
ATOM   3361 N ND1 . HIS   B 1 81  ? -90.90931  -8.95409  -96.31642  1.000 12.98692  ? 81  HIS   B ND1 1 
ATOM   3362 C CD2 . HIS   B 1 81  ? -90.42708  -6.93574  -95.63096  1.000 8.97037   ? 81  HIS   B CD2 1 
ATOM   3363 C CE1 . HIS   B 1 81  ? -90.65315  -9.03090  -95.02225  1.000 12.12240  ? 81  HIS   B CE1 1 
ATOM   3364 N NE2 . HIS   B 1 81  ? -90.37008  -7.81691  -94.58114  1.000 12.77683  ? 81  HIS   B NE2 1 
ATOM   3365 N N   . THR   B 1 82  ? -94.08957  -6.06392  -96.83389  1.000 15.32217  ? 82  THR   B N   1 
ATOM   3366 C CA  . THR   B 1 82  ? -94.84883  -7.31805  -96.75501  1.000 11.83106  ? 82  THR   B CA  1 
ATOM   3367 C C   . THR   B 1 82  ? -96.27842  -6.89364  -96.40808  1.000 14.58316  ? 82  THR   B C   1 
ATOM   3368 O O   . THR   B 1 82  ? -96.46450  -5.82369  -95.83491  1.000 16.95545  ? 82  THR   B O   1 
ATOM   3369 C CB  . THR   B 1 82  ? -94.29178  -8.30583  -95.68234  1.000 15.43712  ? 82  THR   B CB  1 
ATOM   3370 O OG1 . THR   B 1 82  ? -95.13652  -9.46149  -95.59629  1.000 16.03532  ? 82  THR   B OG1 1 
ATOM   3371 C CG2 . THR   B 1 82  ? -94.19699  -7.64836  -94.30536  1.000 7.34183   ? 82  THR   B CG2 1 
ATOM   3372 N N   . LEU   B 1 83  ? -97.28236  -7.71327  -96.74154  1.000 15.43749  ? 83  LEU   B N   1 
ATOM   3373 C CA  . LEU   B 1 83  ? -98.67703  -7.27898  -96.65274  1.000 14.54565  ? 83  LEU   B CA  1 
ATOM   3374 C C   . LEU   B 1 83  ? -99.26995  -7.49918  -95.26514  1.000 18.10009  ? 83  LEU   B C   1 
ATOM   3375 O O   . LEU   B 1 83  ? -99.78244  -6.55713  -94.65622  1.000 11.08833  ? 83  LEU   B O   1 
ATOM   3376 C CB  . LEU   B 1 83  ? -99.53366  -8.00019  -97.70135  1.000 15.24034  ? 83  LEU   B CB  1 
ATOM   3377 C CG  . LEU   B 1 83  ? -99.18381  -7.62295  -99.13905  1.000 15.11596  ? 83  LEU   B CG  1 
ATOM   3378 C CD1 . LEU   B 1 83  ? -99.96141  -8.47812  -100.14219 1.000 13.25312  ? 83  LEU   B CD1 1 
ATOM   3379 C CD2 . LEU   B 1 83  ? -99.43639  -6.15505  -99.34379  1.000 10.18722  ? 83  LEU   B CD2 1 
ATOM   3380 N N   . VAL   B 1 84  ? -99.23177  -8.73503  -94.76288  1.000 13.81078  ? 84  VAL   B N   1 
ATOM   3381 C CA  . VAL   B 1 84  ? -99.88734  -9.07779  -93.50837  1.000 13.14519  ? 84  VAL   B CA  1 
ATOM   3382 C C   . VAL   B 1 84  ? -98.85650  -9.66482  -92.55520  1.000 19.28655  ? 84  VAL   B C   1 
ATOM   3383 O O   . VAL   B 1 84  ? -98.29801  -10.74362 -92.80896  1.000 18.89230  ? 84  VAL   B O   1 
ATOM   3384 C CB  . VAL   B 1 84  ? -101.06871 -10.03181 -93.71778  1.000 15.63294  ? 84  VAL   B CB  1 
ATOM   3385 C CG1 . VAL   B 1 84  ? -101.66435 -10.45549 -92.36154  1.000 8.74326   ? 84  VAL   B CG1 1 
ATOM   3386 C CG2 . VAL   B 1 84  ? -102.12982 -9.33330  -94.58377  1.000 8.68381   ? 84  VAL   B CG2 1 
ATOM   3387 N N   . TRP   B 1 85  ? -98.63060  -8.95521  -91.44897  1.000 13.05810  ? 85  TRP   B N   1 
ATOM   3388 C CA  . TRP   B 1 85  ? -97.58988  -9.24044  -90.47339  1.000 17.40538  ? 85  TRP   B CA  1 
ATOM   3389 C C   . TRP   B 1 85  ? -98.04724  -8.69319  -89.12363  1.000 17.45403  ? 85  TRP   B C   1 
ATOM   3390 O O   . TRP   B 1 85  ? -98.64358  -7.61379  -89.07019  1.000 14.33012  ? 85  TRP   B O   1 
ATOM   3391 C CB  . TRP   B 1 85  ? -96.27653  -8.57918  -90.90251  1.000 14.20411  ? 85  TRP   B CB  1 
ATOM   3392 C CG  . TRP   B 1 85  ? -95.07114  -9.00931  -90.15412  1.000 16.50709  ? 85  TRP   B CG  1 
ATOM   3393 C CD1 . TRP   B 1 85  ? -94.89829  -10.17563 -89.47595  1.000 18.24588  ? 85  TRP   B CD1 1 
ATOM   3394 C CD2 . TRP   B 1 85  ? -93.84834  -8.27878  -90.02266  1.000 16.91184  ? 85  TRP   B CD2 1 
ATOM   3395 N NE1 . TRP   B 1 85  ? -93.64307  -10.22369 -88.93514  1.000 22.25272  ? 85  TRP   B NE1 1 
ATOM   3396 C CE2 . TRP   B 1 85  ? -92.97519  -9.06905  -89.25098  1.000 18.29477  ? 85  TRP   B CE2 1 
ATOM   3397 C CE3 . TRP   B 1 85  ? -93.40537  -7.03401  -90.49066  1.000 16.20565  ? 85  TRP   B CE3 1 
ATOM   3398 C CZ2 . TRP   B 1 85  ? -91.67813  -8.65597  -88.92295  1.000 19.06588  ? 85  TRP   B CZ2 1 
ATOM   3399 C CZ3 . TRP   B 1 85  ? -92.12263  -6.62023  -90.16989  1.000 24.35965  ? 85  TRP   B CZ3 1 
ATOM   3400 C CH2 . TRP   B 1 85  ? -91.26924  -7.43110  -89.38620  1.000 19.02274  ? 85  TRP   B CH2 1 
ATOM   3401 N N   . HIS   B 1 86  ? -97.77014  -9.42786  -88.03824  1.000 15.58384  ? 86  HIS   B N   1 
ATOM   3402 C CA  . HIS   B 1 86  ? -98.08539  -8.89759  -86.70829  1.000 17.33336  ? 86  HIS   B CA  1 
ATOM   3403 C C   . HIS   B 1 86  ? -97.27963  -7.63425  -86.40294  1.000 18.14039  ? 86  HIS   B C   1 
ATOM   3404 O O   . HIS   B 1 86  ? -97.72136  -6.78640  -85.61527  1.000 16.54211  ? 86  HIS   B O   1 
ATOM   3405 C CB  . HIS   B 1 86  ? -97.82323  -9.95808  -85.63151  1.000 15.74398  ? 86  HIS   B CB  1 
ATOM   3406 C CG  . HIS   B 1 86  ? -96.40326  -10.44583 -85.61256  1.000 24.63405  ? 86  HIS   B CG  1 
ATOM   3407 N ND1 . HIS   B 1 86  ? -95.98662  -11.55336 -86.32093  1.000 17.88274  ? 86  HIS   B ND1 1 
ATOM   3408 C CD2 . HIS   B 1 86  ? -95.29610  -9.94754  -85.00771  1.000 20.30474  ? 86  HIS   B CD2 1 
ATOM   3409 C CE1 . HIS   B 1 86  ? -94.69000  -11.72384 -86.14377  1.000 19.57339  ? 86  HIS   B CE1 1 
ATOM   3410 N NE2 . HIS   B 1 86  ? -94.24564  -10.76061 -85.35501  1.000 22.89547  ? 86  HIS   B NE2 1 
ATOM   3411 N N   . ASN   B 1 87  ? -96.09963  -7.48908  -87.00142  1.000 16.71144  ? 87  ASN   B N   1 
ATOM   3412 C CA  . ASN   B 1 87  ? -95.26030  -6.33281  -86.71762  1.000 18.90635  ? 87  ASN   B CA  1 
ATOM   3413 C C   . ASN   B 1 87  ? -95.52312  -5.19537  -87.68942  1.000 15.39113  ? 87  ASN   B C   1 
ATOM   3414 O O   . ASN   B 1 87  ? -96.05830  -5.38509  -88.78223  1.000 12.80277  ? 87  ASN   B O   1 
ATOM   3415 C CB  . ASN   B 1 87  ? -93.78349  -6.69528  -86.77360  1.000 16.75218  ? 87  ASN   B CB  1 
ATOM   3416 C CG  . ASN   B 1 87  ? -93.26729  -7.16222  -85.44124  1.000 24.61767  ? 87  ASN   B CG  1 
ATOM   3417 O OD1 . ASN   B 1 87  ? -94.01561  -7.21471  -84.45783  1.000 19.32026  ? 87  ASN   B OD1 1 
ATOM   3418 N ND2 . ASN   B 1 87  ? -91.99424  -7.52837  -85.39675  1.000 21.02545  ? 87  ASN   B ND2 1 
ATOM   3419 N N   . GLN   B 1 88  ? -95.12620  -3.99815  -87.26013  1.000 17.88113  ? 88  GLN   B N   1 
ATOM   3420 C CA  . GLN   B 1 88  ? -95.15068  -2.79415  -88.08389  1.000 16.90828  ? 88  GLN   B CA  1 
ATOM   3421 C C   . GLN   B 1 88  ? -96.49122  -2.65459  -88.79995  1.000 19.76940  ? 88  GLN   B C   1 
ATOM   3422 O O   . GLN   B 1 88  ? -96.56930  -2.38947  -90.00072  1.000 18.39524  ? 88  GLN   B O   1 
ATOM   3423 C CB  . GLN   B 1 88  ? -93.96528  -2.78009  -89.05470  1.000 10.40130  ? 88  GLN   B CB  1 
ATOM   3424 C CG  . GLN   B 1 88  ? -92.62485  -2.79765  -88.32179  1.000 17.35359  ? 88  GLN   B CG  1 
ATOM   3425 C CD  . GLN   B 1 88  ? -91.41654  -2.60342  -89.22304  1.000 17.72543  ? 88  GLN   B CD  1 
ATOM   3426 O OE1 . GLN   B 1 88  ? -90.66114  -3.54288  -89.48690  1.000 15.99983  ? 88  GLN   B OE1 1 
ATOM   3427 N NE2 . GLN   B 1 88  ? -91.21405  -1.38122  -89.67495  1.000 12.94737  ? 88  GLN   B NE2 1 
ATOM   3428 N N   . THR   B 1 89  ? -97.56108  -2.87128  -88.03868  1.000 17.27401  ? 89  THR   B N   1 
ATOM   3429 C CA  . THR   B 1 89  ? -98.91910  -2.64278  -88.50663  1.000 18.99203  ? 89  THR   B CA  1 
ATOM   3430 C C   . THR   B 1 89  ? -99.58231  -1.67605  -87.53782  1.000 16.18376  ? 89  THR   B C   1 
ATOM   3431 O O   . THR   B 1 89  ? -99.66218  -1.98122  -86.33653  1.000 22.31508  ? 89  THR   B O   1 
ATOM   3432 C CB  . THR   B 1 89  ? -99.71352  -3.95110  -88.59875  1.000 18.01982  ? 89  THR   B CB  1 
ATOM   3433 O OG1 . THR   B 1 89  ? -99.11205  -4.81633  -89.56788  1.000 14.86416  ? 89  THR   B OG1 1 
ATOM   3434 C CG2 . THR   B 1 89  ? -101.14770 -3.68476  -89.00486  1.000 10.88818  ? 89  THR   B CG2 1 
ATOM   3435 N N   . PRO   B 1 90  ? -100.06374 -0.52130  -87.99984  1.000 17.07890  ? 90  PRO   B N   1 
ATOM   3436 C CA  . PRO   B 1 90  ? -100.64166 0.47533   -87.08568  1.000 19.70504  ? 90  PRO   B CA  1 
ATOM   3437 C C   . PRO   B 1 90  ? -101.83685 -0.06403  -86.30837  1.000 21.41269  ? 90  PRO   B C   1 
ATOM   3438 O O   . PRO   B 1 90  ? -102.53737 -0.98640  -86.73419  1.000 22.63037  ? 90  PRO   B O   1 
ATOM   3439 C CB  . PRO   B 1 90  ? -101.07913 1.61571   -88.01844  1.000 20.68781  ? 90  PRO   B CB  1 
ATOM   3440 C CG  . PRO   B 1 90  ? -100.49837 1.31317   -89.35762  1.000 20.53336  ? 90  PRO   B CG  1 
ATOM   3441 C CD  . PRO   B 1 90  ? -100.24914 -0.16020  -89.41381  1.000 17.68975  ? 90  PRO   B CD  1 
ATOM   3442 N N   . ASP   B 1 91  ? -102.07852 0.56541   -85.15747  1.000 22.09674  ? 91  ASP   B N   1 
ATOM   3443 C CA  . ASP   B 1 91  ? -103.16506 0.15431   -84.27543  1.000 27.08306  ? 91  ASP   B CA  1 
ATOM   3444 C C   . ASP   B 1 91  ? -104.53707 0.33148   -84.90732  1.000 21.98363  ? 91  ASP   B C   1 
ATOM   3445 O O   . ASP   B 1 91  ? -105.44110 -0.46385  -84.62576  1.000 20.97080  ? 91  ASP   B O   1 
ATOM   3446 C CB  . ASP   B 1 91  ? -103.10667 0.94573   -82.97217  1.000 26.73629  ? 91  ASP   B CB  1 
ATOM   3447 C CG  . ASP   B 1 91  ? -101.93031 0.55384   -82.11561  1.000 33.81461  ? 91  ASP   B CG  1 
ATOM   3448 O OD1 . ASP   B 1 91  ? -101.52662 -0.62835  -82.18012  1.000 31.39226  ? 91  ASP   B OD1 1 
ATOM   3449 O OD2 . ASP   B 1 91  ? -101.41460 1.42226   -81.37962  1.000 43.55540  ? 91  ASP   B OD2 1 
ATOM   3450 N N   . TRP   B 1 92  ? -104.71973 1.36019   -85.74935  1.000 17.35091  ? 92  TRP   B N   1 
ATOM   3451 C CA  . TRP   B 1 92  ? -106.05043 1.64452   -86.28388  1.000 20.08996  ? 92  TRP   B CA  1 
ATOM   3452 C C   . TRP   B 1 92  ? -106.64959 0.44270   -86.99534  1.000 25.84932  ? 92  TRP   B C   1 
ATOM   3453 O O   . TRP   B 1 92  ? -107.87296 0.27225   -86.99231  1.000 25.03715  ? 92  TRP   B O   1 
ATOM   3454 C CB  . TRP   B 1 92  ? -106.01707 2.84644   -87.23319  1.000 20.33298  ? 92  TRP   B CB  1 
ATOM   3455 C CG  . TRP   B 1 92  ? -105.38166 2.61624   -88.60602  1.000 22.73561  ? 92  TRP   B CG  1 
ATOM   3456 C CD1 . TRP   B 1 92  ? -104.13738 3.03537   -89.01130  1.000 23.20915  ? 92  TRP   B CD1 1 
ATOM   3457 C CD2 . TRP   B 1 92  ? -105.97592 1.97942   -89.75104  1.000 19.22904  ? 92  TRP   B CD2 1 
ATOM   3458 N NE1 . TRP   B 1 92  ? -103.92215 2.68988   -90.32251  1.000 16.38889  ? 92  TRP   B NE1 1 
ATOM   3459 C CE2 . TRP   B 1 92  ? -105.02230 2.02498   -90.79728  1.000 15.63032  ? 92  TRP   B CE2 1 
ATOM   3460 C CE3 . TRP   B 1 92  ? -107.21534 1.36842   -89.99209  1.000 21.32322  ? 92  TRP   B CE3 1 
ATOM   3461 C CZ2 . TRP   B 1 92  ? -105.26825 1.48051   -92.07093  1.000 14.04458  ? 92  TRP   B CZ2 1 
ATOM   3462 C CZ3 . TRP   B 1 92  ? -107.45779 0.81336   -91.25224  1.000 22.65046  ? 92  TRP   B CZ3 1 
ATOM   3463 C CH2 . TRP   B 1 92  ? -106.48633 0.88464   -92.28166  1.000 22.89534  ? 92  TRP   B CH2 1 
ATOM   3464 N N   . VAL   B 1 93  ? -105.80400 -0.39731  -87.59920  1.000 21.57908  ? 93  VAL   B N   1 
ATOM   3465 C CA  . VAL   B 1 93  ? -106.26896 -1.51877  -88.41141  1.000 19.24536  ? 93  VAL   B CA  1 
ATOM   3466 C C   . VAL   B 1 93  ? -107.25284 -2.38378  -87.64060  1.000 22.15685  ? 93  VAL   B C   1 
ATOM   3467 O O   . VAL   B 1 93  ? -108.23522 -2.88647  -88.19845  1.000 22.47916  ? 93  VAL   B O   1 
ATOM   3468 C CB  . VAL   B 1 93  ? -105.06142 -2.34485  -88.89604  1.000 14.78780  ? 93  VAL   B CB  1 
ATOM   3469 C CG1 . VAL   B 1 93  ? -105.52096 -3.61232  -89.55820  1.000 17.11276  ? 93  VAL   B CG1 1 
ATOM   3470 C CG2 . VAL   B 1 93  ? -104.22677 -1.52212  -89.85718  1.000 21.47939  ? 93  VAL   B CG2 1 
ATOM   3471 N N   . PHE   B 1 94  ? -107.00726 -2.57241  -86.35143  1.000 19.81115  ? 94  PHE   B N   1 
ATOM   3472 C CA  . PHE   B 1 94  ? -107.77723 -3.51568  -85.56103  1.000 28.01121  ? 94  PHE   B CA  1 
ATOM   3473 C C   . PHE   B 1 94  ? -108.90613 -2.87214  -84.74972  1.000 31.67392  ? 94  PHE   B C   1 
ATOM   3474 O O   . PHE   B 1 94  ? -109.76076 -3.60257  -84.22762  1.000 23.90402  ? 94  PHE   B O   1 
ATOM   3475 C CB  . PHE   B 1 94  ? -106.81220 -4.29184  -84.65363  1.000 20.62451  ? 94  PHE   B CB  1 
ATOM   3476 C CG  . PHE   B 1 94  ? -105.66830 -4.91751  -85.41695  1.000 24.17942  ? 94  PHE   B CG  1 
ATOM   3477 C CD1 . PHE   B 1 94  ? -105.88017 -6.04426  -86.20661  1.000 21.35325  ? 94  PHE   B CD1 1 
ATOM   3478 C CD2 . PHE   B 1 94  ? -104.40063 -4.35678  -85.39141  1.000 24.44872  ? 94  PHE   B CD2 1 
ATOM   3479 C CE1 . PHE   B 1 94  ? -104.85391 -6.60404  -86.94353  1.000 22.57249  ? 94  PHE   B CE1 1 
ATOM   3480 C CE2 . PHE   B 1 94  ? -103.35987 -4.92795  -86.12278  1.000 18.67214  ? 94  PHE   B CE2 1 
ATOM   3481 C CZ  . PHE   B 1 94  ? -103.58983 -6.04247  -86.89914  1.000 16.39821  ? 94  PHE   B CZ  1 
ATOM   3482 N N   . GLN   B 1 95  ? -108.96328 -1.53951  -84.67381  1.000 20.99932  ? 95  GLN   B N   1 
ATOM   3483 C CA  . GLN   B 1 95  ? -109.87527 -0.83233  -83.78359  1.000 30.58324  ? 95  GLN   B CA  1 
ATOM   3484 C C   . GLN   B 1 95  ? -111.00156 -0.13057  -84.53749  1.000 32.38857  ? 95  GLN   B C   1 
ATOM   3485 O O   . GLN   B 1 95  ? -110.85132 0.26446   -85.69806  1.000 27.59428  ? 95  GLN   B O   1 
ATOM   3486 C CB  . GLN   B 1 95  ? -109.11645 0.19943   -82.95449  1.000 28.47525  ? 95  GLN   B CB  1 
ATOM   3487 C CG  . GLN   B 1 95  ? -108.19552 -0.43473  -81.94639  1.000 39.03474  ? 95  GLN   B CG  1 
ATOM   3488 C CD  . GLN   B 1 95  ? -107.08740 0.50218   -81.49005  1.000 56.47013  ? 95  GLN   B CD  1 
ATOM   3489 O OE1 . GLN   B 1 95  ? -106.90722 1.59976   -82.03980  1.000 44.89472  ? 95  GLN   B OE1 1 
ATOM   3490 N NE2 . GLN   B 1 95  ? -106.32657 0.06604   -80.48283  1.000 57.72891  ? 95  GLN   B NE2 1 
ATOM   3491 N N   . ASP   B 1 96  ? -112.13904 0.02831   -83.85627  1.000 42.72437  ? 96  ASP   B N   1 
ATOM   3492 C CA  . ASP   B 1 96  ? -113.22223 0.88150   -84.33198  1.000 34.58503  ? 96  ASP   B CA  1 
ATOM   3493 C C   . ASP   B 1 96  ? -113.07440 2.27509   -83.71617  1.000 37.66162  ? 96  ASP   B C   1 
ATOM   3494 O O   . ASP   B 1 96  ? -112.05806 2.60589   -83.09756  1.000 41.32224  ? 96  ASP   B O   1 
ATOM   3495 C CB  . ASP   B 1 96  ? -114.57984 0.24691   -84.02473  1.000 30.92846  ? 96  ASP   B CB  1 
ATOM   3496 C CG  . ASP   B 1 96  ? -114.80402 -0.00505  -82.52658  1.000 50.51828  ? 96  ASP   B CG  1 
ATOM   3497 O OD1 . ASP   B 1 96  ? -114.13510 0.63661   -81.68319  1.000 40.64703  ? 96  ASP   B OD1 1 
ATOM   3498 O OD2 . ASP   B 1 96  ? -115.65823 -0.86227  -82.19128  1.000 42.13821  ? 96  ASP   B OD2 1 
ATOM   3499 N N   . GLY   B 1 97  ? -114.10026 3.10928   -83.86436  1.000 48.22346  ? 97  GLY   B N   1 
ATOM   3500 C CA  . GLY   B 1 97  ? -114.02766 4.45271   -83.30759  1.000 52.74352  ? 97  GLY   B CA  1 
ATOM   3501 C C   . GLY   B 1 97  ? -113.75256 4.46463   -81.81508  1.000 50.79734  ? 97  GLY   B C   1 
ATOM   3502 O O   . GLY   B 1 97  ? -113.02973 5.33052   -81.31574  1.000 48.69629  ? 97  GLY   B O   1 
ATOM   3503 N N   . GLN   B 1 98  ? -114.29754 3.48714   -81.09082  1.000 58.77383  ? 98  GLN   B N   1 
ATOM   3504 C CA  . GLN   B 1 98  ? -114.21162 3.41722   -79.63502  1.000 61.71656  ? 98  GLN   B CA  1 
ATOM   3505 C C   . GLN   B 1 98  ? -113.01529 2.60996   -79.15189  1.000 59.36399  ? 98  GLN   B C   1 
ATOM   3506 O O   . GLN   B 1 98  ? -112.95143 2.26377   -77.96614  1.000 48.67903  ? 98  GLN   B O   1 
ATOM   3507 C CB  . GLN   B 1 98  ? -115.50197 2.82312   -79.05370  1.000 52.19157  ? 98  GLN   B CB  1 
ATOM   3508 C CG  . GLN   B 1 98  ? -116.74165 3.72128   -79.19715  1.000 76.30603  ? 98  GLN   B CG  1 
ATOM   3509 C CD  . GLN   B 1 98  ? -117.01754 4.14886   -80.64049  1.000 86.09159  ? 98  GLN   B CD  1 
ATOM   3510 O OE1 . GLN   B 1 98  ? -117.25346 3.31141   -81.51638  1.000 74.61070  ? 98  GLN   B OE1 1 
ATOM   3511 N NE2 . GLN   B 1 98  ? -116.96571 5.45638   -80.89380  1.000 73.36061  ? 98  GLN   B NE2 1 
ATOM   3512 N N   . GLY   B 1 99  ? -112.07518 2.29798   -80.04324  1.000 57.70307  ? 99  GLY   B N   1 
ATOM   3513 C CA  . GLY   B 1 99  ? -110.90082 1.53244   -79.68292  1.000 56.29268  ? 99  GLY   B CA  1 
ATOM   3514 C C   . GLY   B 1 99  ? -111.13507 0.06207   -79.41401  1.000 62.60645  ? 99  GLY   B C   1 
ATOM   3515 O O   . GLY   B 1 99  ? -110.16348 -0.65535  -79.13803  1.000 59.73751  ? 99  GLY   B O   1 
ATOM   3516 N N   . HIS   B 1 100 ? -112.38436 -0.40660  -79.46686  1.000 53.62797  ? 100 HIS   B N   1 
ATOM   3517 C CA  . HIS   B 1 100 ? -112.67452 -1.83216  -79.39980  1.000 45.36627  ? 100 HIS   B CA  1 
ATOM   3518 C C   . HIS   B 1 100 ? -112.19927 -2.53701  -80.66820  1.000 35.36085  ? 100 HIS   B C   1 
ATOM   3519 O O   . HIS   B 1 100 ? -111.98609 -1.91989  -81.71385  1.000 40.63972  ? 100 HIS   B O   1 
ATOM   3520 C CB  . HIS   B 1 100 ? -114.17367 -2.07498  -79.21938  1.000 49.96631  ? 100 HIS   B CB  1 
ATOM   3521 C CG  . HIS   B 1 100 ? -114.78384 -1.27948  -78.10954  1.000 70.51769  ? 100 HIS   B CG  1 
ATOM   3522 N ND1 . HIS   B 1 100 ? -114.12966 -1.04032  -76.91858  1.000 78.08536  ? 100 HIS   B ND1 1 
ATOM   3523 C CD2 . HIS   B 1 100 ? -115.98206 -0.65629  -78.01412  1.000 53.34354  ? 100 HIS   B CD2 1 
ATOM   3524 C CE1 . HIS   B 1 100 ? -114.90256 -0.31057  -76.13398  1.000 68.32130  ? 100 HIS   B CE1 1 
ATOM   3525 N NE2 . HIS   B 1 100 ? -116.03048 -0.06173  -76.77590  1.000 76.17504  ? 100 HIS   B NE2 1 
ATOM   3526 N N   . PHE   B 1 101 ? -112.05285 -3.85307  -80.57065  1.000 29.48167  ? 101 PHE   B N   1 
ATOM   3527 C CA  . PHE   B 1 101 ? -111.60926 -4.63630  -81.71250  1.000 33.50138  ? 101 PHE   B CA  1 
ATOM   3528 C C   . PHE   B 1 101 ? -112.73846 -4.78306  -82.72419  1.000 33.24720  ? 101 PHE   B C   1 
ATOM   3529 O O   . PHE   B 1 101 ? -113.88329 -5.07066  -82.36275  1.000 36.45955  ? 101 PHE   B O   1 
ATOM   3530 C CB  . PHE   B 1 101 ? -111.10828 -6.00600  -81.25795  1.000 28.34109  ? 101 PHE   B CB  1 
ATOM   3531 C CG  . PHE   B 1 101 ? -109.74145 -5.96502  -80.63485  1.000 35.20694  ? 101 PHE   B CG  1 
ATOM   3532 C CD1 . PHE   B 1 101 ? -108.76351 -5.14350  -81.15243  1.000 32.11229  ? 101 PHE   B CD1 1 
ATOM   3533 C CD2 . PHE   B 1 101 ? -109.43590 -6.73805  -79.52736  1.000 45.78574  ? 101 PHE   B CD2 1 
ATOM   3534 C CE1 . PHE   B 1 101 ? -107.49380 -5.09336  -80.57755  1.000 39.46707  ? 101 PHE   B CE1 1 
ATOM   3535 C CE2 . PHE   B 1 101 ? -108.16708 -6.69189  -78.94981  1.000 46.54320  ? 101 PHE   B CE2 1 
ATOM   3536 C CZ  . PHE   B 1 101 ? -107.19914 -5.86738  -79.47991  1.000 31.09028  ? 101 PHE   B CZ  1 
ATOM   3537 N N   . VAL   B 1 102 ? -112.41577 -4.57869  -83.99888  1.000 27.98460  ? 102 VAL   B N   1 
ATOM   3538 C CA  . VAL   B 1 102 ? -113.41809 -4.69913  -85.04322  1.000 20.08778  ? 102 VAL   B CA  1 
ATOM   3539 C C   . VAL   B 1 102 ? -113.78223 -6.16341  -85.20886  1.000 23.12650  ? 102 VAL   B C   1 
ATOM   3540 O O   . VAL   B 1 102 ? -113.14418 -7.05291  -84.63766  1.000 25.74533  ? 102 VAL   B O   1 
ATOM   3541 C CB  . VAL   B 1 102 ? -112.93597 -4.09386  -86.37124  1.000 24.14806  ? 102 VAL   B CB  1 
ATOM   3542 C CG1 . VAL   B 1 102 ? -112.68274 -2.60577  -86.20057  1.000 24.56201  ? 102 VAL   B CG1 1 
ATOM   3543 C CG2 . VAL   B 1 102 ? -111.67653 -4.83144  -86.88977  1.000 22.31866  ? 102 VAL   B CG2 1 
ATOM   3544 N N   . SER   B 1 103 ? -114.83312 -6.41320  -85.97386  1.000 31.93958  ? 103 SER   B N   1 
ATOM   3545 C CA  . SER   B 1 103 ? -115.29184 -7.75543  -86.26144  1.000 28.91515  ? 103 SER   B CA  1 
ATOM   3546 C C   . SER   B 1 103 ? -114.37752 -8.42132  -87.29038  1.000 27.26526  ? 103 SER   B C   1 
ATOM   3547 O O   . SER   B 1 103 ? -113.51720 -7.78374  -87.90442  1.000 25.63516  ? 103 SER   B O   1 
ATOM   3548 C CB  . SER   B 1 103 ? -116.71740 -7.70506  -86.79769  1.000 20.17123  ? 103 SER   B CB  1 
ATOM   3549 O OG  . SER   B 1 103 ? -116.70684 -7.22404  -88.12995  1.000 24.11759  ? 103 SER   B OG  1 
ATOM   3550 N N   . ARG   B 1 104 ? -114.61090 -9.71820  -87.50473  1.000 25.29626  ? 104 ARG   B N   1 
ATOM   3551 C CA  . ARG   B 1 104 ? -113.94012 -10.43264 -88.58501  1.000 30.91119  ? 104 ARG   B CA  1 
ATOM   3552 C C   . ARG   B 1 104 ? -114.21201 -9.77871  -89.93531  1.000 28.08077  ? 104 ARG   B C   1 
ATOM   3553 O O   . ARG   B 1 104 ? -113.29181 -9.56244  -90.73078  1.000 29.14811  ? 104 ARG   B O   1 
ATOM   3554 C CB  . ARG   B 1 104 ? -114.38860 -11.89245 -88.59474  1.000 25.57015  ? 104 ARG   B CB  1 
ATOM   3555 C CG  . ARG   B 1 104 ? -114.20900 -12.57035 -89.91936  1.000 23.82393  ? 104 ARG   B CG  1 
ATOM   3556 C CD  . ARG   B 1 104 ? -114.71998 -14.00146 -89.86958  1.000 16.90483  ? 104 ARG   B CD  1 
ATOM   3557 N NE  . ARG   B 1 104 ? -114.66552 -14.62750 -91.18888  1.000 19.36292  ? 104 ARG   B NE  1 
ATOM   3558 C CZ  . ARG   B 1 104 ? -113.68989 -15.43596 -91.59108  1.000 30.60585  ? 104 ARG   B CZ  1 
ATOM   3559 N NH1 . ARG   B 1 104 ? -112.67816 -15.73437 -90.77653  1.000 29.67433  ? 104 ARG   B NH1 1 
ATOM   3560 N NH2 . ARG   B 1 104 ? -113.72508 -15.95066 -92.80803  1.000 25.94984  ? 104 ARG   B NH2 1 
ATOM   3561 N N   . ASP   B 1 105 ? -115.47104 -9.44363  -90.20855  1.000 26.36354  ? 105 ASP   B N   1 
ATOM   3562 C CA  . ASP   B 1 105 ? -115.81847 -8.94614  -91.53624  1.000 26.86391  ? 105 ASP   B CA  1 
ATOM   3563 C C   . ASP   B 1 105 ? -115.18784 -7.58709  -91.80375  1.000 24.66499  ? 105 ASP   B C   1 
ATOM   3564 O O   . ASP   B 1 105 ? -114.76641 -7.30623  -92.92861  1.000 27.02184  ? 105 ASP   B O   1 
ATOM   3565 C CB  . ASP   B 1 105 ? -117.34096 -8.87138  -91.69132  1.000 22.93205  ? 105 ASP   B CB  1 
ATOM   3566 C CG  . ASP   B 1 105 ? -117.96126 -10.21841 -91.99454  1.000 26.18431  ? 105 ASP   B CG  1 
ATOM   3567 O OD1 . ASP   B 1 105 ? -117.20268 -11.15785 -92.34158  1.000 24.42616  ? 105 ASP   B OD1 1 
ATOM   3568 O OD2 . ASP   B 1 105 ? -119.20660 -10.33470 -91.88190  1.000 40.89643  ? 105 ASP   B OD2 1 
ATOM   3569 N N   . VAL   B 1 106 ? -115.13025 -6.72528  -90.79029  1.000 24.04345  ? 106 VAL   B N   1 
ATOM   3570 C CA  . VAL   B 1 106 ? -114.50890 -5.42073  -90.97944  1.000 31.80125  ? 106 VAL   B CA  1 
ATOM   3571 C C   . VAL   B 1 106 ? -113.01016 -5.57473  -91.21323  1.000 28.65073  ? 106 VAL   B C   1 
ATOM   3572 O O   . VAL   B 1 106 ? -112.43783 -4.92893  -92.10309  1.000 22.29706  ? 106 VAL   B O   1 
ATOM   3573 C CB  . VAL   B 1 106 ? -114.81042 -4.50759  -89.77804  1.000 23.73092  ? 106 VAL   B CB  1 
ATOM   3574 C CG1 . VAL   B 1 106 ? -113.96297 -3.25699  -89.84776  1.000 21.22828  ? 106 VAL   B CG1 1 
ATOM   3575 C CG2 . VAL   B 1 106 ? -116.28278 -4.14478  -89.76532  1.000 20.92580  ? 106 VAL   B CG2 1 
ATOM   3576 N N   . LEU   B 1 107 ? -112.35120 -6.44473  -90.43724  1.000 23.90052  ? 107 LEU   B N   1 
ATOM   3577 C CA  . LEU   B 1 107 ? -110.91730 -6.62544  -90.62732  1.000 20.47458  ? 107 LEU   B CA  1 
ATOM   3578 C C   . LEU   B 1 107 ? -110.62566 -7.18574  -92.00918  1.000 19.37776  ? 107 LEU   B C   1 
ATOM   3579 O O   . LEU   B 1 107 ? -109.71246 -6.71345  -92.68904  1.000 18.69513  ? 107 LEU   B O   1 
ATOM   3580 C CB  . LEU   B 1 107 ? -110.32723 -7.52259  -89.54068  1.000 20.32029  ? 107 LEU   B CB  1 
ATOM   3581 C CG  . LEU   B 1 107 ? -108.79037 -7.47607  -89.51074  1.000 19.74464  ? 107 LEU   B CG  1 
ATOM   3582 C CD1 . LEU   B 1 107 ? -108.28120 -6.04315  -89.59236  1.000 16.31837  ? 107 LEU   B CD1 1 
ATOM   3583 C CD2 . LEU   B 1 107 ? -108.23171 -8.16681  -88.27244  1.000 25.42210  ? 107 LEU   B CD2 1 
ATOM   3584 N N   . LEU   B 1 108 ? -111.42650 -8.15107  -92.46993  1.000 22.66555  ? 108 LEU   B N   1 
ATOM   3585 C CA  . LEU   B 1 108 ? -111.24464 -8.65393  -93.82938  1.000 21.71854  ? 108 LEU   B CA  1 
ATOM   3586 C C   . LEU   B 1 108 ? -111.43677 -7.54591  -94.86471  1.000 23.36641  ? 108 LEU   B C   1 
ATOM   3587 O O   . LEU   B 1 108 ? -110.67788 -7.46147  -95.83704  1.000 21.20300  ? 108 LEU   B O   1 
ATOM   3588 C CB  . LEU   B 1 108 ? -112.19291 -9.82256  -94.09568  1.000 23.53370  ? 108 LEU   B CB  1 
ATOM   3589 C CG  . LEU   B 1 108 ? -111.82768 -11.14272 -93.39759  1.000 26.52957  ? 108 LEU   B CG  1 
ATOM   3590 C CD1 . LEU   B 1 108 ? -112.87724 -12.23702 -93.65509  1.000 24.27097  ? 108 LEU   B CD1 1 
ATOM   3591 C CD2 . LEU   B 1 108 ? -110.46434 -11.62349 -93.80218  1.000 13.29216  ? 108 LEU   B CD2 1 
ATOM   3592 N N   . GLU   B 1 109 ? -112.43054 -6.67037  -94.66902  1.000 27.20296  ? 109 GLU   B N   1 
ATOM   3593 C CA  . GLU   B 1 109 ? -112.61077 -5.56225  -95.60762  1.000 24.89305  ? 109 GLU   B CA  1 
ATOM   3594 C C   . GLU   B 1 109 ? -111.40114 -4.63582  -95.60722  1.000 22.68369  ? 109 GLU   B C   1 
ATOM   3595 O O   . GLU   B 1 109 ? -110.93520 -4.20661  -96.66898  1.000 27.95340  ? 109 GLU   B O   1 
ATOM   3596 C CB  . GLU   B 1 109 ? -113.87042 -4.77690  -95.27575  1.000 21.68563  ? 109 GLU   B CB  1 
ATOM   3597 C CG  . GLU   B 1 109 ? -115.10304 -5.24324  -96.02395  1.000 53.80380  ? 109 GLU   B CG  1 
ATOM   3598 C CD  . GLU   B 1 109 ? -116.40139 -4.87780  -95.30049  1.000 68.82878  ? 109 GLU   B CD  1 
ATOM   3599 O OE1 . GLU   B 1 109 ? -116.42649 -3.82602  -94.60116  1.000 46.16281  ? 109 GLU   B OE1 1 
ATOM   3600 O OE2 . GLU   B 1 109 ? -117.38618 -5.65242  -95.42771  1.000 53.59639  ? 109 GLU   B OE2 1 
ATOM   3601 N N   . ARG   B 1 110 ? -110.88851 -4.30712  -94.42228  1.000 24.04868  ? 110 ARG   B N   1 
ATOM   3602 C CA  . ARG   B 1 110 ? -109.69947 -3.46841  -94.32697  1.000 17.72245  ? 110 ARG   B CA  1 
ATOM   3603 C C   . ARG   B 1 110 ? -108.48315 -4.16026  -94.93394  1.000 20.53551  ? 110 ARG   B C   1 
ATOM   3604 O O   . ARG   B 1 110 ? -107.70922 -3.53310  -95.66469  1.000 16.23624  ? 110 ARG   B O   1 
ATOM   3605 C CB  . ARG   B 1 110 ? -109.44017 -3.10887  -92.86714  1.000 12.93602  ? 110 ARG   B CB  1 
ATOM   3606 C CG  . ARG   B 1 110 ? -110.41125 -2.11979  -92.29654  1.000 17.50682  ? 110 ARG   B CG  1 
ATOM   3607 C CD  . ARG   B 1 110 ? -110.27171 -1.98346  -90.78977  1.000 17.67388  ? 110 ARG   B CD  1 
ATOM   3608 N NE  . ARG   B 1 110 ? -111.12670 -0.91718  -90.27414  1.000 27.55182  ? 110 ARG   B NE  1 
ATOM   3609 C CZ  . ARG   B 1 110 ? -111.15286 -0.51270  -89.00652  1.000 29.37589  ? 110 ARG   B CZ  1 
ATOM   3610 N NH1 . ARG   B 1 110 ? -110.36534 -1.07836  -88.09801  1.000 21.34033  ? 110 ARG   B NH1 1 
ATOM   3611 N NH2 . ARG   B 1 110 ? -111.97308 0.46438   -88.64659  1.000 30.09718  ? 110 ARG   B NH2 1 
ATOM   3612 N N   . MET   B 1 111 ? -108.29412 -5.45204  -94.64065  1.000 18.77851  ? 111 MET   B N   1 
ATOM   3613 C CA  . MET   B 1 111 ? -107.16757 -6.18096  -95.21184  1.000 13.23688  ? 111 MET   B CA  1 
ATOM   3614 C C   . MET   B 1 111 ? -107.24699 -6.18848  -96.72923  1.000 20.34378  ? 111 MET   B C   1 
ATOM   3615 O O   . MET   B 1 111 ? -106.25643 -5.91518  -97.42293  1.000 19.13561  ? 111 MET   B O   1 
ATOM   3616 C CB  . MET   B 1 111 ? -107.12994 -7.60968  -94.67939  1.000 13.27322  ? 111 MET   B CB  1 
ATOM   3617 C CG  . MET   B 1 111 ? -106.08791 -8.50312  -95.36649  1.000 11.87882  ? 111 MET   B CG  1 
ATOM   3618 S SD  . MET   B 1 111 ? -106.34323 -10.26741 -95.05876  1.000 20.55706  ? 111 MET   B SD  1 
ATOM   3619 C CE  . MET   B 1 111 ? -105.76158 -10.37155 -93.35678  1.000 10.64793  ? 111 MET   B CE  1 
ATOM   3620 N N   . LYS   B 1 112 ? -108.43458 -6.48077  -97.26013  1.000 22.05622  ? 112 LYS   B N   1 
ATOM   3621 C CA  . LYS   B 1 112 ? -108.63002 -6.51291  -98.70772  1.000 24.53767  ? 112 LYS   B CA  1 
ATOM   3622 C C   . LYS   B 1 112 ? -108.35304 -5.15533  -99.34137  1.000 20.09693  ? 112 LYS   B C   1 
ATOM   3623 O O   . LYS   B 1 112 ? -107.69671 -5.06918  -100.38654 1.000 23.63340  ? 112 LYS   B O   1 
ATOM   3624 C CB  . LYS   B 1 112 ? -110.05265 -6.97595  -99.03845  1.000 20.59776  ? 112 LYS   B CB  1 
ATOM   3625 C CG  . LYS   B 1 112 ? -110.35473 -6.95123  -100.53353 1.000 25.86133  ? 112 LYS   B CG  1 
ATOM   3626 C CD  . LYS   B 1 112 ? -111.52779 -7.84990  -100.89714 1.000 42.23710  ? 112 LYS   B CD  1 
ATOM   3627 C CE  . LYS   B 1 112 ? -112.49758 -7.14178  -101.84595 1.000 44.64033  ? 112 LYS   B CE  1 
ATOM   3628 N NZ  . LYS   B 1 112 ? -113.08102 -8.08529  -102.84113 1.000 50.74963  ? 112 LYS   B NZ  1 
ATOM   3629 N N   . CYS   B 1 113 ? -108.85386 -4.07939  -98.73432  1.000 14.61833  ? 113 CYS   B N   1 
ATOM   3630 C CA  . CYS   B 1 113 ? -108.67264 -2.77650  -99.35827  1.000 16.87324  ? 113 CYS   B CA  1 
ATOM   3631 C C   . CYS   B 1 113 ? -107.19383 -2.39064  -99.38675  1.000 21.01781  ? 113 CYS   B C   1 
ATOM   3632 O O   . CYS   B 1 113 ? -106.69402 -1.87998  -100.39952 1.000 22.94697  ? 113 CYS   B O   1 
ATOM   3633 C CB  . CYS   B 1 113 ? -109.50511 -1.73059  -98.63662  1.000 20.08924  ? 113 CYS   B CB  1 
ATOM   3634 S SG  . CYS   B 1 113 ? -109.43883 -0.10936  -99.40244  1.000 34.00447  ? 113 CYS   B SG  1 
ATOM   3635 N N   . HIS   B 1 114 ? -106.46961 -2.65489  -98.29213  1.000 15.65508  ? 114 HIS   B N   1 
ATOM   3636 C CA  . HIS   B 1 114 ? -105.02848 -2.41819  -98.26211  1.000 14.77260  ? 114 HIS   B CA  1 
ATOM   3637 C C   . HIS   B 1 114 ? -104.31338 -3.25454  -99.31880  1.000 16.36411  ? 114 HIS   B C   1 
ATOM   3638 O O   . HIS   B 1 114 ? -103.53205 -2.73042  -100.12163 1.000 14.75623  ? 114 HIS   B O   1 
ATOM   3639 C CB  . HIS   B 1 114 ? -104.47350 -2.72749  -96.86837  1.000 14.74224  ? 114 HIS   B CB  1 
ATOM   3640 C CG  . HIS   B 1 114 ? -103.00067 -2.50493  -96.74921  1.000 19.43385  ? 114 HIS   B CG  1 
ATOM   3641 N ND1 . HIS   B 1 114 ? -102.45797 -1.27799  -96.42362  1.000 16.32596  ? 114 HIS   B ND1 1 
ATOM   3642 C CD2 . HIS   B 1 114 ? -101.95213 -3.35199  -96.90847  1.000 12.97046  ? 114 HIS   B CD2 1 
ATOM   3643 C CE1 . HIS   B 1 114 ? -101.14062 -1.37809  -96.38838  1.000 12.28450  ? 114 HIS   B CE1 1 
ATOM   3644 N NE2 . HIS   B 1 114 ? -100.80980 -2.62673  -96.66924  1.000 12.35850  ? 114 HIS   B NE2 1 
ATOM   3645 N N   . ILE   B 1 115 ? -104.55547 -4.56707  -99.32420  1.000 14.78428  ? 115 ILE   B N   1 
ATOM   3646 C CA  . ILE   B 1 115 ? -103.84967 -5.43651  -100.25891 1.000 11.39399  ? 115 ILE   B CA  1 
ATOM   3647 C C   . ILE   B 1 115 ? -104.14656 -5.02135  -101.69342 1.000 19.81352  ? 115 ILE   B C   1 
ATOM   3648 O O   . ILE   B 1 115 ? -103.24206 -4.96349  -102.53649 1.000 24.20728  ? 115 ILE   B O   1 
ATOM   3649 C CB  . ILE   B 1 115 ? -104.22539 -6.90673  -100.00016 1.000 15.60369  ? 115 ILE   B CB  1 
ATOM   3650 C CG1 . ILE   B 1 115 ? -103.65794 -7.38271  -98.66183  1.000 16.22686  ? 115 ILE   B CG1 1 
ATOM   3651 C CG2 . ILE   B 1 115 ? -103.78299 -7.80142  -101.15051 1.000 12.33983  ? 115 ILE   B CG2 1 
ATOM   3652 C CD1 . ILE   B 1 115 ? -104.06404 -8.82396  -98.28502  1.000 14.08106  ? 115 ILE   B CD1 1 
ATOM   3653 N N   A SER   B 1 116 ? -105.41223 -4.70286  -101.98994 0.417 18.84506  ? 116 SER   B N   1 
ATOM   3654 N N   B SER   B 1 116 ? -105.41352 -4.70185  -101.98617 0.583 18.81505  ? 116 SER   B N   1 
ATOM   3655 C CA  A SER   B 1 116 ? -105.79341 -4.34876  -103.35595 0.417 19.92963  ? 116 SER   B CA  1 
ATOM   3656 C CA  B SER   B 1 116 ? -105.80592 -4.34358  -103.34773 0.583 19.95140  ? 116 SER   B CA  1 
ATOM   3657 C C   A SER   B 1 116 ? -105.11847 -3.05716  -103.80720 0.417 16.52327  ? 116 SER   B C   1 
ATOM   3658 C C   B SER   B 1 116 ? -105.12260 -3.05786  -103.80493 0.583 16.32079  ? 116 SER   B C   1 
ATOM   3659 O O   A SER   B 1 116 ? -104.55822 -2.99003  -104.90599 0.417 16.22625  ? 116 SER   B O   1 
ATOM   3660 O O   B SER   B 1 116 ? -104.56155 -2.99496  -104.90322 0.583 15.78459  ? 116 SER   B O   1 
ATOM   3661 C CB  A SER   B 1 116 ? -107.31515 -4.22584  -103.46210 0.417 18.60024  ? 116 SER   B CB  1 
ATOM   3662 C CB  B SER   B 1 116 ? -107.32882 -4.20455  -103.42942 0.583 18.59136  ? 116 SER   B CB  1 
ATOM   3663 O OG  A SER   B 1 116 ? -107.94175 -5.47022  -103.21301 0.417 19.60525  ? 116 SER   B OG  1 
ATOM   3664 O OG  B SER   B 1 116 ? -107.73076 -3.72617  -104.69838 0.583 18.23605  ? 116 SER   B OG  1 
ATOM   3665 N N   . THR   B 1 117 ? -105.17030 -2.01674  -102.97547 1.000 13.84572  ? 117 THR   B N   1 
ATOM   3666 C CA  . THR   B 1 117 ? -104.57575 -0.74267  -103.35578 1.000 14.89967  ? 117 THR   B CA  1 
ATOM   3667 C C   . THR   B 1 117 ? -103.07377 -0.88698  -103.56075 1.000 16.93981  ? 117 THR   B C   1 
ATOM   3668 O O   . THR   B 1 117 ? -102.52322 -0.42286  -104.56370 1.000 19.86377  ? 117 THR   B O   1 
ATOM   3669 C CB  . THR   B 1 117 ? -104.87344 0.30042   -102.27767 1.000 18.80813  ? 117 THR   B CB  1 
ATOM   3670 O OG1 . THR   B 1 117 ? -106.24622 0.19850   -101.88300 1.000 16.06555  ? 117 THR   B OG1 1 
ATOM   3671 C CG2 . THR   B 1 117 ? -104.56756 1.70491   -102.76740 1.000 16.52020  ? 117 THR   B CG2 1 
ATOM   3672 N N   . VAL   B 1 118 ? -102.40394 -1.56832  -102.63058 1.000 15.62652  ? 118 VAL   B N   1 
ATOM   3673 C CA  . VAL   B 1 118 ? -100.95299 -1.65067  -102.65647 1.000 14.40333  ? 118 VAL   B CA  1 
ATOM   3674 C C   . VAL   B 1 118 ? -100.49351 -2.51567  -103.81879 1.000 19.24247  ? 118 VAL   B C   1 
ATOM   3675 O O   . VAL   B 1 118 ? -99.56586  -2.15727  -104.55615 1.000 20.57022  ? 118 VAL   B O   1 
ATOM   3676 C CB  . VAL   B 1 118 ? -100.42958 -2.18915  -101.31109 1.000 19.30154  ? 118 VAL   B CB  1 
ATOM   3677 C CG1 . VAL   B 1 118 ? -98.95953  -2.54764  -101.41915 1.000 14.40565  ? 118 VAL   B CG1 1 
ATOM   3678 C CG2 . VAL   B 1 118 ? -100.66958 -1.17755  -100.19742 1.000 12.01595  ? 118 VAL   B CG2 1 
ATOM   3679 N N   . VAL   B 1 119 ? -101.11688 -3.68011  -103.98680 1.000 16.45959  ? 119 VAL   B N   1 
ATOM   3680 C CA  . VAL   B 1 119 ? -100.65607 -4.59619  -105.01843 1.000 16.41453  ? 119 VAL   B CA  1 
ATOM   3681 C C   . VAL   B 1 119 ? -100.92416 -4.01831  -106.40273 1.000 19.50277  ? 119 VAL   B C   1 
ATOM   3682 O O   . VAL   B 1 119 ? -100.05005 -4.03566  -107.27296 1.000 19.42026  ? 119 VAL   B O   1 
ATOM   3683 C CB  . VAL   B 1 119 ? -101.31979 -5.96846  -104.83013 1.000 18.05140  ? 119 VAL   B CB  1 
ATOM   3684 C CG1 . VAL   B 1 119 ? -101.05699 -6.86871  -106.05277 1.000 17.93043  ? 119 VAL   B CG1 1 
ATOM   3685 C CG2 . VAL   B 1 119 ? -100.83866 -6.60423  -103.53725 1.000 15.97944  ? 119 VAL   B CG2 1 
ATOM   3686 N N   . ARG   B 1 120 ? -102.12248 -3.46455  -106.61380 1.000 19.12915  ? 120 ARG   B N   1 
ATOM   3687 C CA  . ARG   B 1 120 ? -102.47537 -2.92115  -107.92353 1.000 23.67703  ? 120 ARG   B CA  1 
ATOM   3688 C C   . ARG   B 1 120 ? -101.53963 -1.80200  -108.33573 1.000 16.99287  ? 120 ARG   B C   1 
ATOM   3689 O O   . ARG   B 1 120 ? -101.20385 -1.67977  -109.51554 1.000 22.47444  ? 120 ARG   B O   1 
ATOM   3690 C CB  . ARG   B 1 120 ? -103.91579 -2.41006  -107.92715 1.000 20.10209  ? 120 ARG   B CB  1 
ATOM   3691 C CG  . ARG   B 1 120 ? -104.92762 -3.51291  -108.03766 1.000 31.82054  ? 120 ARG   B CG  1 
ATOM   3692 C CD  . ARG   B 1 120 ? -106.34634 -2.97804  -107.98069 1.000 38.01982  ? 120 ARG   B CD  1 
ATOM   3693 N NE  . ARG   B 1 120 ? -107.24895 -4.00073  -107.46192 1.000 43.45143  ? 120 ARG   B NE  1 
ATOM   3694 C CZ  . ARG   B 1 120 ? -107.65892 -5.04986  -108.17418 1.000 55.13058  ? 120 ARG   B CZ  1 
ATOM   3695 N NH1 . ARG   B 1 120 ? -107.23185 -5.19086  -109.43418 1.000 38.69618  ? 120 ARG   B NH1 1 
ATOM   3696 N NH2 . ARG   B 1 120 ? -108.48426 -5.95626  -107.63122 1.000 41.37462  ? 120 ARG   B NH2 1 
ATOM   3697 N N   . ARG   B 1 121 ? -101.11605 -0.96662  -107.38328 1.000 16.74304  ? 121 ARG   B N   1 
ATOM   3698 C CA  . ARG   B 1 121 ? -100.26522 0.15969   -107.74425 1.000 17.02858  ? 121 ARG   B CA  1 
ATOM   3699 C C   . ARG   B 1 121 ? -98.97405  -0.30604  -108.39442 1.000 21.74697  ? 121 ARG   B C   1 
ATOM   3700 O O   . ARG   B 1 121 ? -98.46321  0.35860   -109.30329 1.000 22.92534  ? 121 ARG   B O   1 
ATOM   3701 C CB  . ARG   B 1 121 ? -99.95156  1.01301   -106.51974 1.000 15.63646  ? 121 ARG   B CB  1 
ATOM   3702 C CG  . ARG   B 1 121 ? -99.06310  2.21352   -106.86141 1.000 16.05228  ? 121 ARG   B CG  1 
ATOM   3703 C CD  . ARG   B 1 121 ? -98.85595  3.10019   -105.64656 1.000 14.83363  ? 121 ARG   B CD  1 
ATOM   3704 N NE  . ARG   B 1 121 ? -98.08785  4.31924   -105.90759 1.000 15.39503  ? 121 ARG   B NE  1 
ATOM   3705 C CZ  . ARG   B 1 121 ? -98.54475  5.36967   -106.58238 1.000 17.95166  ? 121 ARG   B CZ  1 
ATOM   3706 N NH1 . ARG   B 1 121 ? -99.76827  5.35402   -107.10118 1.000 15.37546  ? 121 ARG   B NH1 1 
ATOM   3707 N NH2 . ARG   B 1 121 ? -97.77917  6.44141   -106.73924 1.000 15.70397  ? 121 ARG   B NH2 1 
ATOM   3708 N N   . TYR   B 1 122 ? -98.44400  -1.45068  -107.96397 1.000 16.99694  ? 122 TYR   B N   1 
ATOM   3709 C CA  . TYR   B 1 122 ? -97.17094  -1.94980  -108.47156 1.000 24.32897  ? 122 TYR   B CA  1 
ATOM   3710 C C   . TYR   B 1 122 ? -97.32335  -3.14712  -109.41008 1.000 19.85055  ? 122 TYR   B C   1 
ATOM   3711 O O   . TYR   B 1 122 ? -96.31934  -3.75693  -109.77825 1.000 19.78381  ? 122 TYR   B O   1 
ATOM   3712 C CB  . TYR   B 1 122 ? -96.24700  -2.27599  -107.28671 1.000 17.17261  ? 122 TYR   B CB  1 
ATOM   3713 C CG  . TYR   B 1 122 ? -95.97811  -1.04099  -106.43847 1.000 16.90138  ? 122 TYR   B CG  1 
ATOM   3714 C CD1 . TYR   B 1 122 ? -95.25574  0.03371   -106.95664 1.000 15.40747  ? 122 TYR   B CD1 1 
ATOM   3715 C CD2 . TYR   B 1 122 ? -96.49309  -0.92079  -105.15392 1.000 10.76942  ? 122 TYR   B CD2 1 
ATOM   3716 C CE1 . TYR   B 1 122 ? -95.02700  1.17078   -106.21018 1.000 10.33456  ? 122 TYR   B CE1 1 
ATOM   3717 C CE2 . TYR   B 1 122 ? -96.26983  0.21613   -104.39990 1.000 9.67856   ? 122 TYR   B CE2 1 
ATOM   3718 C CZ  . TYR   B 1 122 ? -95.53816  1.26162   -104.93731 1.000 14.99552  ? 122 TYR   B CZ  1 
ATOM   3719 O OH  . TYR   B 1 122 ? -95.30658  2.40611   -104.19939 1.000 14.17123  ? 122 TYR   B OH  1 
ATOM   3720 N N   . LYS   B 1 123 ? -98.55031  -3.49324  -109.80705 1.000 20.61509  ? 123 LYS   B N   1 
ATOM   3721 C CA  . LYS   B 1 123 ? -98.76738  -4.57145  -110.77011 1.000 25.80780  ? 123 LYS   B CA  1 
ATOM   3722 C C   . LYS   B 1 123 ? -97.88184  -4.38466  -112.00372 1.000 26.88602  ? 123 LYS   B C   1 
ATOM   3723 O O   . LYS   B 1 123 ? -97.70735  -3.27048  -112.50477 1.000 20.44776  ? 123 LYS   B O   1 
ATOM   3724 C CB  . LYS   B 1 123 ? -100.24850 -4.62574  -111.17779 1.000 25.39023  ? 123 LYS   B CB  1 
ATOM   3725 C CG  . LYS   B 1 123 ? -100.62126 -5.91306  -111.89068 1.000 36.77185  ? 123 LYS   B CG  1 
ATOM   3726 C CD  . LYS   B 1 123 ? -101.92996 -5.81649  -112.64738 1.000 33.38776  ? 123 LYS   B CD  1 
ATOM   3727 C CE  . LYS   B 1 123 ? -103.12534 -5.89133  -111.71261 1.000 36.82692  ? 123 LYS   B CE  1 
ATOM   3728 N NZ  . LYS   B 1 123 ? -104.18018 -6.84639  -112.21720 1.000 29.03281  ? 123 LYS   B NZ  1 
ATOM   3729 N N   . GLY   B 1 124 ? -97.27545  -5.47955  -112.46364 1.000 24.41403  ? 124 GLY   B N   1 
ATOM   3730 C CA  . GLY   B 1 124 ? -96.33579  -5.42422  -113.55997 1.000 18.28296  ? 124 GLY   B CA  1 
ATOM   3731 C C   . GLY   B 1 124 ? -94.93615  -4.95731  -113.20603 1.000 33.68420  ? 124 GLY   B C   1 
ATOM   3732 O O   . GLY   B 1 124 ? -94.01034  -5.15055  -114.00499 1.000 37.39015  ? 124 GLY   B O   1 
ATOM   3733 N N   . LYS   B 1 125 ? -94.73344  -4.35327  -112.04233 1.000 26.79912  ? 125 LYS   B N   1 
ATOM   3734 C CA  . LYS   B 1 125 ? -93.38812  -3.96963  -111.63676 1.000 29.97772  ? 125 LYS   B CA  1 
ATOM   3735 C C   . LYS   B 1 125 ? -92.83312  -4.81050  -110.49514 1.000 27.07855  ? 125 LYS   B C   1 
ATOM   3736 O O   . LYS   B 1 125 ? -91.62121  -5.02582  -110.43414 1.000 18.61363  ? 125 LYS   B O   1 
ATOM   3737 C CB  . LYS   B 1 125 ? -93.35904  -2.48387  -111.25656 1.000 21.18138  ? 125 LYS   B CB  1 
ATOM   3738 C CG  . LYS   B 1 125 ? -93.83234  -1.60490  -112.41239 1.000 30.80773  ? 125 LYS   B CG  1 
ATOM   3739 C CD  . LYS   B 1 125 ? -93.38519  -0.16436  -112.28840 1.000 30.80544  ? 125 LYS   B CD  1 
ATOM   3740 C CE  . LYS   B 1 125 ? -94.53300  0.72301   -111.88750 1.000 40.13423  ? 125 LYS   B CE  1 
ATOM   3741 N NZ  . LYS   B 1 125 ? -94.33544  2.12260   -112.35255 1.000 47.58808  ? 125 LYS   B NZ  1 
ATOM   3742 N N   . ILE   B 1 126 ? -93.69122  -5.29888  -109.60667 1.000 19.87113  ? 126 ILE   B N   1 
ATOM   3743 C CA  . ILE   B 1 126 ? -93.31057  -6.16605  -108.50502 1.000 17.44614  ? 126 ILE   B CA  1 
ATOM   3744 C C   . ILE   B 1 126 ? -93.74475  -7.56698  -108.89102 1.000 23.16426  ? 126 ILE   B C   1 
ATOM   3745 O O   . ILE   B 1 126 ? -94.93127  -7.80105  -109.15126 1.000 25.55298  ? 126 ILE   B O   1 
ATOM   3746 C CB  . ILE   B 1 126 ? -93.96585  -5.71309  -107.18939 1.000 17.32331  ? 126 ILE   B CB  1 
ATOM   3747 C CG1 . ILE   B 1 126 ? -93.41994  -4.34918  -106.78471 1.000 18.07327  ? 126 ILE   B CG1 1 
ATOM   3748 C CG2 . ILE   B 1 126 ? -93.76816  -6.73506  -106.08702 1.000 13.54589  ? 126 ILE   B CG2 1 
ATOM   3749 C CD1 . ILE   B 1 126 ? -93.80090  -3.93608  -105.39654 1.000 20.06647  ? 126 ILE   B CD1 1 
ATOM   3750 N N   . TYR   B 1 127 ? -92.79637  -8.49952  -108.95867 1.000 21.49235  ? 127 TYR   B N   1 
ATOM   3751 C CA  . TYR   B 1 127 ? -93.17293  -9.81323  -109.44986 1.000 19.70350  ? 127 TYR   B CA  1 
ATOM   3752 C C   . TYR   B 1 127 ? -93.56571  -10.78768 -108.35142 1.000 26.90948  ? 127 TYR   B C   1 
ATOM   3753 O O   . TYR   B 1 127 ? -94.17471  -11.81948 -108.66130 1.000 26.23215  ? 127 TYR   B O   1 
ATOM   3754 C CB  . TYR   B 1 127 ? -92.05315  -10.40183 -110.30855 1.000 28.48773  ? 127 TYR   B CB  1 
ATOM   3755 C CG  . TYR   B 1 127 ? -90.92881  -11.07611 -109.57139 1.000 24.55514  ? 127 TYR   B CG  1 
ATOM   3756 C CD1 . TYR   B 1 127 ? -89.86983  -10.33096 -109.06625 1.000 26.31579  ? 127 TYR   B CD1 1 
ATOM   3757 C CD2 . TYR   B 1 127 ? -90.89335  -12.46684 -109.42520 1.000 28.41754  ? 127 TYR   B CD2 1 
ATOM   3758 C CE1 . TYR   B 1 127 ? -88.80016  -10.94394 -108.40141 1.000 29.28761  ? 127 TYR   B CE1 1 
ATOM   3759 C CE2 . TYR   B 1 127 ? -89.83322  -13.09266 -108.75541 1.000 37.17956  ? 127 TYR   B CE2 1 
ATOM   3760 C CZ  . TYR   B 1 127 ? -88.78728  -12.32019 -108.25143 1.000 32.14770  ? 127 TYR   B CZ  1 
ATOM   3761 O OH  . TYR   B 1 127 ? -87.72531  -12.90647 -107.60131 1.000 35.62044  ? 127 TYR   B OH  1 
ATOM   3762 N N   . CYS   B 1 128 ? -93.26616  -10.49163 -107.08567 1.000 20.29634  ? 128 CYS   B N   1 
ATOM   3763 C CA  . CYS   B 1 128 ? -93.70261  -11.37783 -106.01592 1.000 16.74985  ? 128 CYS   B CA  1 
ATOM   3764 C C   . CYS   B 1 128 ? -93.94533  -10.57444 -104.74200 1.000 14.83649  ? 128 CYS   B C   1 
ATOM   3765 O O   . CYS   B 1 128 ? -93.41914  -9.47549  -104.56477 1.000 18.95173  ? 128 CYS   B O   1 
ATOM   3766 C CB  . CYS   B 1 128 ? -92.68134  -12.49860 -105.77467 1.000 16.07820  ? 128 CYS   B CB  1 
ATOM   3767 S SG  . CYS   B 1 128 ? -91.09153  -11.92762 -105.10244 1.000 18.09682  ? 128 CYS   B SG  1 
ATOM   3768 N N   . TRP   B 1 129 ? -94.75117  -11.13841 -103.85005 1.000 13.60602  ? 129 TRP   B N   1 
ATOM   3769 C CA  . TRP   B 1 129 ? -95.15923  -10.46567 -102.62699 1.000 11.90232  ? 129 TRP   B CA  1 
ATOM   3770 C C   . TRP   B 1 129 ? -95.01201  -11.43010 -101.45948 1.000 16.31209  ? 129 TRP   B C   1 
ATOM   3771 O O   . TRP   B 1 129 ? -95.39508  -12.59927 -101.56243 1.000 14.60797  ? 129 TRP   B O   1 
ATOM   3772 C CB  . TRP   B 1 129 ? -96.60578  -9.96336  -102.71630 1.000 14.48619  ? 129 TRP   B CB  1 
ATOM   3773 C CG  . TRP   B 1 129 ? -96.70417  -8.54029  -103.20406 1.000 21.36681  ? 129 TRP   B CG  1 
ATOM   3774 C CD1 . TRP   B 1 129 ? -96.99907  -8.12628  -104.47236 1.000 14.34331  ? 129 TRP   B CD1 1 
ATOM   3775 C CD2 . TRP   B 1 129 ? -96.48781  -7.34443  -102.43119 1.000 15.59965  ? 129 TRP   B CD2 1 
ATOM   3776 N NE1 . TRP   B 1 129 ? -96.98775  -6.75043  -104.53465 1.000 16.20815  ? 129 TRP   B NE1 1 
ATOM   3777 C CE2 . TRP   B 1 129 ? -96.66875  -6.24716  -103.30150 1.000 16.29608  ? 129 TRP   B CE2 1 
ATOM   3778 C CE3 . TRP   B 1 129 ? -96.13879  -7.10089  -101.09645 1.000 14.20468  ? 129 TRP   B CE3 1 
ATOM   3779 C CZ2 . TRP   B 1 129 ? -96.51918  -4.92633  -102.88200 1.000 18.01635  ? 129 TRP   B CZ2 1 
ATOM   3780 C CZ3 . TRP   B 1 129 ? -95.99170  -5.79194  -100.67476 1.000 16.40204  ? 129 TRP   B CZ3 1 
ATOM   3781 C CH2 . TRP   B 1 129 ? -96.18596  -4.71800  -101.56663 1.000 23.58744  ? 129 TRP   B CH2 1 
ATOM   3782 N N   . ASP   B 1 130 ? -94.40985  -10.95391 -100.37104 1.000 16.66267  ? 130 ASP   B N   1 
ATOM   3783 C CA  . ASP   B 1 130 ? -94.48107  -11.64780 -99.08886  1.000 15.65543  ? 130 ASP   B CA  1 
ATOM   3784 C C   . ASP   B 1 130 ? -95.86592  -11.35493 -98.51363  1.000 16.95903  ? 130 ASP   B C   1 
ATOM   3785 O O   . ASP   B 1 130 ? -96.08850  -10.31268 -97.89331  1.000 18.27523  ? 130 ASP   B O   1 
ATOM   3786 C CB  . ASP   B 1 130 ? -93.37004  -11.17810 -98.15633  1.000 14.18509  ? 130 ASP   B CB  1 
ATOM   3787 C CG  . ASP   B 1 130 ? -91.97616  -11.67673 -98.57422  1.000 20.50073  ? 130 ASP   B CG  1 
ATOM   3788 O OD1 . ASP   B 1 130 ? -91.87485  -12.69372 -99.30102  1.000 14.34354  ? 130 ASP   B OD1 1 
ATOM   3789 O OD2 . ASP   B 1 130 ? -90.97315  -11.04477 -98.15279  1.000 16.40855  ? 130 ASP   B OD2 1 
ATOM   3790 N N   . VAL   B 1 131 ? -96.81894  -12.25635 -98.74085  1.000 13.28992  ? 131 VAL   B N   1 
ATOM   3791 C CA  . VAL   B 1 131 ? -98.18319  -11.98201 -98.31179  1.000 14.07671  ? 131 VAL   B CA  1 
ATOM   3792 C C   . VAL   B 1 131 ? -98.29815  -12.12787 -96.80280  1.000 14.91422  ? 131 VAL   B C   1 
ATOM   3793 O O   . VAL   B 1 131 ? -98.84636  -11.25815 -96.11571  1.000 17.49676  ? 131 VAL   B O   1 
ATOM   3794 C CB  . VAL   B 1 131 ? -99.17387  -12.89624 -99.05039  1.000 17.38705  ? 131 VAL   B CB  1 
ATOM   3795 C CG1 . VAL   B 1 131 ? -100.62477 -12.57914 -98.62642  1.000 14.22454  ? 131 VAL   B CG1 1 
ATOM   3796 C CG2 . VAL   B 1 131 ? -98.97936  -12.74317 -100.54316 1.000 11.27538  ? 131 VAL   B CG2 1 
ATOM   3797 N N   . ILE   B 1 132 ? -97.77846  -13.22116 -96.26265  1.000 17.45469  ? 132 ILE   B N   1 
ATOM   3798 C CA  . ILE   B 1 132 ? -97.81014  -13.46870 -94.83068  1.000 16.98124  ? 132 ILE   B CA  1 
ATOM   3799 C C   . ILE   B 1 132 ? -96.37020  -13.52735 -94.34884  1.000 22.72318  ? 132 ILE   B C   1 
ATOM   3800 O O   . ILE   B 1 132 ? -95.53902  -14.21902 -94.94794  1.000 16.30611  ? 132 ILE   B O   1 
ATOM   3801 C CB  . ILE   B 1 132 ? -98.56142  -14.76495 -94.49349  1.000 13.80292  ? 132 ILE   B CB  1 
ATOM   3802 C CG1 . ILE   B 1 132 ? -100.04491 -14.63775 -94.87656  1.000 16.54130  ? 132 ILE   B CG1 1 
ATOM   3803 C CG2 . ILE   B 1 132 ? -98.35880  -15.12962 -93.01428  1.000 11.09986  ? 132 ILE   B CG2 1 
ATOM   3804 C CD1 . ILE   B 1 132 ? -100.83999 -13.58727 -94.09013  1.000 15.03264  ? 132 ILE   B CD1 1 
ATOM   3805 N N   . ASN   B 1 133 ? -96.07446  -12.78923 -93.28432  1.000 15.28170  ? 133 ASN   B N   1 
ATOM   3806 C CA  . ASN   B 1 133 ? -94.74971  -12.77060 -92.68657  1.000 16.59403  ? 133 ASN   B CA  1 
ATOM   3807 C C   . ASN   B 1 133 ? -94.82391  -13.35019 -91.27958  1.000 17.73166  ? 133 ASN   B C   1 
ATOM   3808 O O   . ASN   B 1 133 ? -95.59599  -12.86514 -90.44613  1.000 20.74246  ? 133 ASN   B O   1 
ATOM   3809 C CB  . ASN   B 1 133 ? -94.19227  -11.34791 -92.65587  1.000 14.47869  ? 133 ASN   B CB  1 
ATOM   3810 C CG  . ASN   B 1 133 ? -92.68366  -11.32705 -92.60539  1.000 15.82327  ? 133 ASN   B CG  1 
ATOM   3811 O OD1 . ASN   B 1 133 ? -92.02138  -12.18779 -93.18092  1.000 17.04237  ? 133 ASN   B OD1 1 
ATOM   3812 N ND2 . ASN   B 1 133 ? -92.13200  -10.33506 -91.92882  1.000 15.98634  ? 133 ASN   B ND2 1 
ATOM   3813 N N   . GLU   B 1 134 ? -94.05138  -14.40791 -91.03154  1.000 20.44042  ? 134 GLU   B N   1 
ATOM   3814 C CA  . GLU   B 1 134 ? -93.70484  -14.84253 -89.67211  1.000 21.71746  ? 134 GLU   B CA  1 
ATOM   3815 C C   . GLU   B 1 134 ? -94.93839  -15.17956 -88.82867  1.000 24.68150  ? 134 GLU   B C   1 
ATOM   3816 O O   . GLU   B 1 134 ? -95.08051  -14.71689 -87.69090  1.000 19.10224  ? 134 GLU   B O   1 
ATOM   3817 C CB  . GLU   B 1 134 ? -92.84688  -13.78162 -88.97273  1.000 13.73644  ? 134 GLU   B CB  1 
ATOM   3818 C CG  . GLU   B 1 134 ? -91.57974  -13.42580 -89.73646  1.000 17.44750  ? 134 GLU   B CG  1 
ATOM   3819 C CD  . GLU   B 1 134 ? -90.77812  -12.31242 -89.07479  1.000 20.58729  ? 134 GLU   B CD  1 
ATOM   3820 O OE1 . GLU   B 1 134 ? -91.23368  -11.78247 -88.03125  1.000 18.19712  ? 134 GLU   B OE1 1 
ATOM   3821 O OE2 . GLU   B 1 134 ? -89.69571  -11.97250 -89.59974  1.000 12.80893  ? 134 GLU   B OE2 1 
ATOM   3822 N N   . ALA   B 1 135 ? -95.82129  -16.02344 -89.38192  1.000 20.91646  ? 135 ALA   B N   1 
ATOM   3823 C CA  . ALA   B 1 135 ? -97.02829  -16.43695 -88.66767  1.000 25.35881  ? 135 ALA   B CA  1 
ATOM   3824 C C   . ALA   B 1 135 ? -96.81383  -17.63600 -87.75207  1.000 19.99030  ? 135 ALA   B C   1 
ATOM   3825 O O   . ALA   B 1 135 ? -97.59924  -17.82081 -86.81665  1.000 23.48918  ? 135 ALA   B O   1 
ATOM   3826 C CB  . ALA   B 1 135 ? -98.16266  -16.76025 -89.65332  1.000 16.52085  ? 135 ALA   B CB  1 
ATOM   3827 N N   . VAL   B 1 136 ? -95.76982  -18.44246 -87.98912  1.000 20.36130  ? 136 VAL   B N   1 
ATOM   3828 C CA  . VAL   B 1 136 ? -95.49540  -19.63829 -87.19083  1.000 20.33389  ? 136 VAL   B CA  1 
ATOM   3829 C C   . VAL   B 1 136 ? -94.90125  -19.25906 -85.83693  1.000 19.27770  ? 136 VAL   B C   1 
ATOM   3830 O O   . VAL   B 1 136 ? -94.12503  -18.29931 -85.71995  1.000 19.89215  ? 136 VAL   B O   1 
ATOM   3831 C CB  . VAL   B 1 136 ? -94.57136  -20.58486 -87.97619  1.000 24.94802  ? 136 VAL   B CB  1 
ATOM   3832 C CG1 . VAL   B 1 136 ? -93.96274  -21.65435 -87.07442  1.000 22.53453  ? 136 VAL   B CG1 1 
ATOM   3833 C CG2 . VAL   B 1 136 ? -95.35228  -21.21257 -89.12496  1.000 24.77888  ? 136 VAL   B CG2 1 
ATOM   3834 N N   . ALA   B 1 137 ? -95.27238  -20.01594 -84.80142  1.000 24.07572  ? 137 ALA   B N   1 
ATOM   3835 C CA  . ALA   B 1 137 ? -94.85536  -19.70372 -83.43738  1.000 25.71004  ? 137 ALA   B CA  1 
ATOM   3836 C C   . ALA   B 1 137 ? -93.37752  -20.01071 -83.21860  1.000 29.17708  ? 137 ALA   B C   1 
ATOM   3837 O O   . ALA   B 1 137 ? -92.79170  -20.88415 -83.86827  1.000 29.75419  ? 137 ALA   B O   1 
ATOM   3838 C CB  . ALA   B 1 137 ? -95.69259  -20.48777 -82.42793  1.000 22.19429  ? 137 ALA   B CB  1 
ATOM   3839 N N   . ASP   B 1 138 ? -92.77933  -19.29440 -82.26402  1.000 35.35955  ? 138 ASP   B N   1 
ATOM   3840 C CA  . ASP   B 1 138 ? -91.34681  -19.43137 -82.00713  1.000 32.01865  ? 138 ASP   B CA  1 
ATOM   3841 C C   . ASP   B 1 138 ? -91.02477  -20.71755 -81.25162  1.000 35.49124  ? 138 ASP   B C   1 
ATOM   3842 O O   . ASP   B 1 138 ? -90.16255  -21.49024 -81.67581  1.000 40.40652  ? 138 ASP   B O   1 
ATOM   3843 C CB  . ASP   B 1 138 ? -90.84137  -18.21368 -81.23801  1.000 34.49423  ? 138 ASP   B CB  1 
ATOM   3844 C CG  . ASP   B 1 138 ? -90.58573  -17.02147 -82.14163  1.000 36.10530  ? 138 ASP   B CG  1 
ATOM   3845 O OD1 . ASP   B 1 138 ? -89.58599  -17.05843 -82.90023  1.000 29.69980  ? 138 ASP   B OD1 1 
ATOM   3846 O OD2 . ASP   B 1 138 ? -91.39040  -16.05632 -82.09073  1.000 27.34842  ? 138 ASP   B OD2 1 
ATOM   3847 N N   . GLU   B 1 139 ? -91.69126  -20.95884 -80.12485  1.000 40.69943  ? 139 GLU   B N   1 
ATOM   3848 C CA  . GLU   B 1 139 ? -91.55942  -22.21083 -79.39358  1.000 40.60500  ? 139 GLU   B CA  1 
ATOM   3849 C C   . GLU   B 1 139 ? -92.94732  -22.76005 -79.11608  1.000 47.39750  ? 139 GLU   B C   1 
ATOM   3850 O O   . GLU   B 1 139 ? -93.95434  -22.06230 -79.26347  1.000 52.94682  ? 139 GLU   B O   1 
ATOM   3851 C CB  . GLU   B 1 139 ? -90.80383  -22.03297 -78.06723  1.000 44.16408  ? 139 GLU   B CB  1 
ATOM   3852 C CG  . GLU   B 1 139 ? -89.57502  -21.12938 -78.12891  1.000 47.47356  ? 139 GLU   B CG  1 
ATOM   3853 C CD  . GLU   B 1 139 ? -88.29833  -21.86748 -78.50148  1.000 53.88797  ? 139 GLU   B CD  1 
ATOM   3854 O OE1 . GLU   B 1 139 ? -87.41627  -21.23573 -79.12508  1.000 56.56493  ? 139 GLU   B OE1 1 
ATOM   3855 O OE2 . GLU   B 1 139 ? -88.17149  -23.06763 -78.16903  1.000 59.03250  ? 139 GLU   B OE2 1 
ATOM   3856 N N   . GLY   B 1 140 ? -92.99655  -24.01585 -78.70342  1.000 46.98250  ? 140 GLY   B N   1 
ATOM   3857 C CA  . GLY   B 1 140 ? -94.22943  -24.61415 -78.22789  1.000 47.64651  ? 140 GLY   B CA  1 
ATOM   3858 C C   . GLY   B 1 140 ? -94.78209  -25.65732 -79.18340  1.000 50.60039  ? 140 GLY   B C   1 
ATOM   3859 O O   . GLY   B 1 140 ? -94.11544  -26.12092 -80.11426  1.000 48.01353  ? 140 GLY   B O   1 
ATOM   3860 N N   . ASN   B 1 141 ? -96.03946  -26.02703 -78.93062  1.000 44.01018  ? 141 ASN   B N   1 
ATOM   3861 C CA  . ASN   B 1 141 ? -96.70381  -27.08196 -79.68401  1.000 38.98968  ? 141 ASN   B CA  1 
ATOM   3862 C C   . ASN   B 1 141 ? -97.70475  -26.56213 -80.70282  1.000 47.03649  ? 141 ASN   B C   1 
ATOM   3863 O O   . ASN   B 1 141 ? -98.09423  -27.31423 -81.60289  1.000 43.23829  ? 141 ASN   B O   1 
ATOM   3864 C CB  . ASN   B 1 141 ? -97.43290  -28.04809 -78.73618  1.000 63.46650  ? 141 ASN   B CB  1 
ATOM   3865 C CG  . ASN   B 1 141 ? -96.50438  -29.07688 -78.10158  1.000 60.29271  ? 141 ASN   B CG  1 
ATOM   3866 O OD1 . ASN   B 1 141 ? -95.32541  -29.18289 -78.45493  1.000 51.19833  ? 141 ASN   B OD1 1 
ATOM   3867 N ND2 . ASN   B 1 141 ? -97.04460  -29.85151 -77.16283  1.000 49.52087  ? 141 ASN   B ND2 1 
ATOM   3868 N N   . GLU   B 1 142 ? -98.14520  -25.31586 -80.58100  1.000 52.77222  ? 142 GLU   B N   1 
ATOM   3869 C CA  . GLU   B 1 142 ? -99.08843  -24.77988 -81.54697  1.000 49.79646  ? 142 GLU   B CA  1 
ATOM   3870 C C   . GLU   B 1 142 ? -98.36148  -24.31660 -82.80674  1.000 35.06631  ? 142 GLU   B C   1 
ATOM   3871 O O   . GLU   B 1 142 ? -97.21161  -23.87110 -82.76240  1.000 36.09421  ? 142 GLU   B O   1 
ATOM   3872 C CB  . GLU   B 1 142 ? -99.89158  -23.63323 -80.93344  1.000 48.61345  ? 142 GLU   B CB  1 
ATOM   3873 C CG  . GLU   B 1 142 ? -101.17041 -24.09359 -80.23512  1.000 60.23462  ? 142 GLU   B CG  1 
ATOM   3874 C CD  . GLU   B 1 142 ? -102.39272 -23.25492 -80.61485  1.000 75.23067  ? 142 GLU   B CD  1 
ATOM   3875 O OE1 . GLU   B 1 142 ? -103.47772 -23.84273 -80.83431  1.000 73.00225  ? 142 GLU   B OE1 1 
ATOM   3876 O OE2 . GLU   B 1 142 ? -102.27412 -22.01011 -80.69054  1.000 63.30264  ? 142 GLU   B OE2 1 
ATOM   3877 N N   . LEU   B 1 143 ? -99.04607  -24.45431 -83.94229  1.000 31.25559  ? 143 LEU   B N   1 
ATOM   3878 C CA  . LEU   B 1 143 ? -98.49861  -24.00695 -85.21802  1.000 28.25118  ? 143 LEU   B CA  1 
ATOM   3879 C C   . LEU   B 1 143 ? -98.25417  -22.50143 -85.22377  1.000 32.13216  ? 143 LEU   B C   1 
ATOM   3880 O O   . LEU   B 1 143 ? -97.14536  -22.03612 -85.51727  1.000 33.72091  ? 143 LEU   B O   1 
ATOM   3881 C CB  . LEU   B 1 143 ? -99.45833  -24.39574 -86.33783  1.000 25.84949  ? 143 LEU   B CB  1 
ATOM   3882 C CG  . LEU   B 1 143 ? -99.01997  -24.23285 -87.78912  1.000 35.23437  ? 143 LEU   B CG  1 
ATOM   3883 C CD1 . LEU   B 1 143 ? -97.92017  -25.20249 -88.11452  1.000 30.86740  ? 143 LEU   B CD1 1 
ATOM   3884 C CD2 . LEU   B 1 143 ? -100.20512 -24.46409 -88.70725  1.000 30.94624  ? 143 LEU   B CD2 1 
ATOM   3885 N N   . LEU   B 1 144 ? -99.27381  -21.72605 -84.87790  1.000 30.17680  ? 144 LEU   B N   1 
ATOM   3886 C CA  . LEU   B 1 144 ? -99.30626  -20.29549 -85.13184  1.000 28.35571  ? 144 LEU   B CA  1 
ATOM   3887 C C   . LEU   B 1 144 ? -99.07307  -19.50814 -83.85411  1.000 28.26932  ? 144 LEU   B C   1 
ATOM   3888 O O   . LEU   B 1 144 ? -99.55672  -19.88674 -82.78158  1.000 30.35035  ? 144 LEU   B O   1 
ATOM   3889 C CB  . LEU   B 1 144 ? -100.65414 -19.89283 -85.72850  1.000 26.07600  ? 144 LEU   B CB  1 
ATOM   3890 C CG  . LEU   B 1 144 ? -101.11972 -20.64389 -86.98187  1.000 30.92762  ? 144 LEU   B CG  1 
ATOM   3891 C CD1 . LEU   B 1 144 ? -102.43823 -20.06810 -87.46383  1.000 28.39465  ? 144 LEU   B CD1 1 
ATOM   3892 C CD2 . LEU   B 1 144 ? -100.07926 -20.59179 -88.09546  1.000 20.50723  ? 144 LEU   B CD2 1 
ATOM   3893 N N   . ARG   B 1 145 ? -98.34121  -18.40480 -83.97325  1.000 22.59419  ? 145 ARG   B N   1 
ATOM   3894 C CA  . ARG   B 1 145 ? -98.30534  -17.44789 -82.88136  1.000 24.17242  ? 145 ARG   B CA  1 
ATOM   3895 C C   . ARG   B 1 145 ? -99.64156  -16.71092 -82.80242  1.000 24.72166  ? 145 ARG   B C   1 
ATOM   3896 O O   . ARG   B 1 145 ? -100.35747 -16.59318 -83.80207  1.000 26.10360  ? 145 ARG   B O   1 
ATOM   3897 C CB  . ARG   B 1 145 ? -97.17606  -16.43770 -83.07258  1.000 22.78413  ? 145 ARG   B CB  1 
ATOM   3898 C CG  . ARG   B 1 145 ? -97.34219  -15.51689 -84.28179  1.000 17.15069  ? 145 ARG   B CG  1 
ATOM   3899 C CD  . ARG   B 1 145 ? -96.26792  -14.42035 -84.28728  1.000 22.76522  ? 145 ARG   B CD  1 
ATOM   3900 N NE  . ARG   B 1 145 ? -94.97643  -14.88149 -84.80568  1.000 22.52183  ? 145 ARG   B NE  1 
ATOM   3901 C CZ  . ARG   B 1 145 ? -93.87274  -15.04184 -84.07088  1.000 28.56226  ? 145 ARG   B CZ  1 
ATOM   3902 N NH1 . ARG   B 1 145 ? -93.88401  -14.79529 -82.76310  1.000 22.91568  ? 145 ARG   B NH1 1 
ATOM   3903 N NH2 . ARG   B 1 145 ? -92.75164  -15.46563 -84.64415  1.000 21.42529  ? 145 ARG   B NH2 1 
ATOM   3904 N N   . PRO   B 1 146 ? -100.00549 -16.21039 -81.62839  1.000 20.34727  ? 146 PRO   B N   1 
ATOM   3905 C CA  . PRO   B 1 146 ? -101.17965 -15.33662 -81.54563  1.000 22.43842  ? 146 PRO   B CA  1 
ATOM   3906 C C   . PRO   B 1 146 ? -100.88346 -13.99808 -82.19747  1.000 17.20839  ? 146 PRO   B C   1 
ATOM   3907 O O   . PRO   B 1 146 ? -99.73748  -13.56439 -82.27546  1.000 22.62230  ? 146 PRO   B O   1 
ATOM   3908 C CB  . PRO   B 1 146 ? -101.41102 -15.18593 -80.03787  1.000 23.79205  ? 146 PRO   B CB  1 
ATOM   3909 C CG  . PRO   B 1 146 ? -100.04655 -15.44070 -79.42700  1.000 24.06292  ? 146 PRO   B CG  1 
ATOM   3910 C CD  . PRO   B 1 146 ? -99.37403  -16.44360 -80.31606  1.000 20.60342  ? 146 PRO   B CD  1 
ATOM   3911 N N   . SER   B 1 147 ? -101.93175 -13.35424 -82.69200  1.000 23.51539  ? 147 SER   B N   1 
ATOM   3912 C CA  . SER   B 1 147 ? -101.81803 -12.03702 -83.30339  1.000 24.35692  ? 147 SER   B CA  1 
ATOM   3913 C C   . SER   B 1 147 ? -103.22039 -11.47771 -83.43482  1.000 24.22745  ? 147 SER   B C   1 
ATOM   3914 O O   . SER   B 1 147 ? -104.20857 -12.21684 -83.40532  1.000 28.30334  ? 147 SER   B O   1 
ATOM   3915 C CB  . SER   B 1 147 ? -101.11931 -12.06893 -84.67576  1.000 23.79022  ? 147 SER   B CB  1 
ATOM   3916 O OG  . SER   B 1 147 ? -101.94262 -12.60325 -85.69884  1.000 20.86271  ? 147 SER   B OG  1 
ATOM   3917 N N   . LYS   B 1 148 ? -103.28868 -10.15595 -83.56469  1.000 24.04608  ? 148 LYS   B N   1 
ATOM   3918 C CA  . LYS   B 1 148 ? -104.57310 -9.49175  -83.68684  1.000 19.24342  ? 148 LYS   B CA  1 
ATOM   3919 C C   . LYS   B 1 148 ? -105.25465 -9.83776  -85.00583  1.000 26.92934  ? 148 LYS   B C   1 
ATOM   3920 O O   . LYS   B 1 148 ? -106.48645 -9.94472  -85.04699  1.000 28.07095  ? 148 LYS   B O   1 
ATOM   3921 C CB  . LYS   B 1 148 ? -104.37954 -7.98786  -83.51920  1.000 22.33387  ? 148 LYS   B CB  1 
ATOM   3922 C CG  . LYS   B 1 148 ? -104.06040 -7.59364  -82.07903  1.000 20.55543  ? 148 LYS   B CG  1 
ATOM   3923 C CD  . LYS   B 1 148 ? -104.03772 -6.07868  -81.88323  1.000 25.24711  ? 148 LYS   B CD  1 
ATOM   3924 C CE  . LYS   B 1 148 ? -102.62517 -5.52619  -81.88022  1.000 43.06625  ? 148 LYS   B CE  1 
ATOM   3925 N NZ  . LYS   B 1 148 ? -102.59829 -4.02768  -82.01532  1.000 40.80847  ? 148 LYS   B NZ  1 
ATOM   3926 N N   . TRP   B 1 149 ? -104.48229 -10.03007 -86.08359  1.000 21.48034  ? 149 TRP   B N   1 
ATOM   3927 C CA  . TRP   B 1 149 ? -105.05425 -10.57052 -87.31468  1.000 22.51058  ? 149 TRP   B CA  1 
ATOM   3928 C C   . TRP   B 1 149 ? -105.78241 -11.86918 -87.03328  1.000 24.48421  ? 149 TRP   B C   1 
ATOM   3929 O O   . TRP   B 1 149 ? -106.94449 -12.05414 -87.41527  1.000 32.62692  ? 149 TRP   B O   1 
ATOM   3930 C CB  . TRP   B 1 149 ? -103.96822 -10.85065 -88.35863  1.000 19.20393  ? 149 TRP   B CB  1 
ATOM   3931 C CG  . TRP   B 1 149 ? -103.22020 -9.68222  -88.85298  1.000 23.75663  ? 149 TRP   B CG  1 
ATOM   3932 C CD1 . TRP   B 1 149 ? -101.93856 -9.35192  -88.54603  1.000 16.36372  ? 149 TRP   B CD1 1 
ATOM   3933 C CD2 . TRP   B 1 149 ? -103.68555 -8.68696  -89.77557  1.000 23.55332  ? 149 TRP   B CD2 1 
ATOM   3934 N NE1 . TRP   B 1 149 ? -101.57250 -8.20814  -89.21672  1.000 17.43137  ? 149 TRP   B NE1 1 
ATOM   3935 C CE2 . TRP   B 1 149 ? -102.62451 -7.78142  -89.98060  1.000 17.97711  ? 149 TRP   B CE2 1 
ATOM   3936 C CE3 . TRP   B 1 149 ? -104.89305 -8.47488  -90.44762  1.000 17.38290  ? 149 TRP   B CE3 1 
ATOM   3937 C CZ2 . TRP   B 1 149 ? -102.73534 -6.67624  -90.81991  1.000 13.05922  ? 149 TRP   B CZ2 1 
ATOM   3938 C CZ3 . TRP   B 1 149 ? -104.99884 -7.37699  -91.29037  1.000 15.54935  ? 149 TRP   B CZ3 1 
ATOM   3939 C CH2 . TRP   B 1 149 ? -103.93070 -6.49238  -91.46492  1.000 14.26212  ? 149 TRP   B CH2 1 
ATOM   3940 N N   . ARG   B 1 150 ? -105.08707 -12.79256 -86.37685  1.000 25.04953  ? 150 ARG   B N   1 
ATOM   3941 C CA  . ARG   B 1 150 ? -105.61011 -14.13401 -86.17545  1.000 25.15291  ? 150 ARG   B CA  1 
ATOM   3942 C C   . ARG   B 1 150 ? -106.75020 -14.12487 -85.17075  1.000 19.75085  ? 150 ARG   B C   1 
ATOM   3943 O O   . ARG   B 1 150 ? -107.78444 -14.76117 -85.38509  1.000 27.03722  ? 150 ARG   B O   1 
ATOM   3944 C CB  . ARG   B 1 150 ? -104.46811 -15.04066 -85.72203  1.000 25.28011  ? 150 ARG   B CB  1 
ATOM   3945 C CG  . ARG   B 1 150 ? -104.87118 -16.44587 -85.38229  1.000 27.39092  ? 150 ARG   B CG  1 
ATOM   3946 C CD  . ARG   B 1 150 ? -103.69085 -17.18686 -84.80274  1.000 25.58731  ? 150 ARG   B CD  1 
ATOM   3947 N NE  . ARG   B 1 150 ? -104.07691 -18.51527 -84.36086  1.000 30.93761  ? 150 ARG   B NE  1 
ATOM   3948 C CZ  . ARG   B 1 150 ? -103.55054 -19.12376 -83.30713  1.000 38.16706  ? 150 ARG   B CZ  1 
ATOM   3949 N NH1 . ARG   B 1 150 ? -102.60696 -18.51453 -82.58482  1.000 30.30595  ? 150 ARG   B NH1 1 
ATOM   3950 N NH2 . ARG   B 1 150 ? -103.97389 -20.33520 -82.97283  1.000 34.90228  ? 150 ARG   B NH2 1 
ATOM   3951 N N   . GLN   B 1 151 ? -106.59068 -13.36920 -84.09017  1.000 21.18981  ? 151 GLN   B N   1 
ATOM   3952 C CA  . GLN   B 1 151 ? -107.61835 -13.30434 -83.06167  1.000 24.52187  ? 151 GLN   B CA  1 
ATOM   3953 C C   . GLN   B 1 151 ? -108.93854 -12.79762 -83.62182  1.000 27.78408  ? 151 GLN   B C   1 
ATOM   3954 O O   . GLN   B 1 151 ? -110.00027 -13.34943 -83.31505  1.000 28.49700  ? 151 GLN   B O   1 
ATOM   3955 C CB  . GLN   B 1 151 ? -107.12867 -12.40855 -81.92748  1.000 28.54034  ? 151 GLN   B CB  1 
ATOM   3956 C CG  . GLN   B 1 151 ? -108.17138 -11.97619 -80.92955  1.000 29.25544  ? 151 GLN   B CG  1 
ATOM   3957 C CD  . GLN   B 1 151 ? -107.68255 -10.79827 -80.11601  1.000 45.76792  ? 151 GLN   B CD  1 
ATOM   3958 O OE1 . GLN   B 1 151 ? -106.49796 -10.72130 -79.76520  1.000 49.49056  ? 151 GLN   B OE1 1 
ATOM   3959 N NE2 . GLN   B 1 151 ? -108.57756 -9.85342  -79.83986  1.000 40.14896  ? 151 GLN   B NE2 1 
ATOM   3960 N N   . ILE   B 1 152 ? -108.89604 -11.74675 -84.44196  1.000 26.37889  ? 152 ILE   B N   1 
ATOM   3961 C CA  . ILE   B 1 152 ? -110.13087 -11.15009 -84.93262  1.000 25.59623  ? 152 ILE   B CA  1 
ATOM   3962 C C   . ILE   B 1 152 ? -110.69947 -11.95327 -86.09927  1.000 31.75164  ? 152 ILE   B C   1 
ATOM   3963 O O   . ILE   B 1 152 ? -111.88327 -12.30649 -86.10118  1.000 29.65506  ? 152 ILE   B O   1 
ATOM   3964 C CB  . ILE   B 1 152 ? -109.90217 -9.67575  -85.30558  1.000 21.67231  ? 152 ILE   B CB  1 
ATOM   3965 C CG1 . ILE   B 1 152 ? -109.77177 -8.84000  -84.03951  1.000 16.16299  ? 152 ILE   B CG1 1 
ATOM   3966 C CG2 . ILE   B 1 152 ? -111.05402 -9.15882  -86.15985  1.000 20.87498  ? 152 ILE   B CG2 1 
ATOM   3967 C CD1 . ILE   B 1 152 ? -109.10353 -7.49295  -84.25455  1.000 24.33656  ? 152 ILE   B CD1 1 
ATOM   3968 N N   . ILE   B 1 153 ? -109.87072 -12.28353 -87.09314  1.000 26.09628  ? 153 ILE   B N   1 
ATOM   3969 C CA  . ILE   B 1 153 ? -110.39176 -12.97557 -88.27033  1.000 23.30097  ? 153 ILE   B CA  1 
ATOM   3970 C C   . ILE   B 1 153 ? -110.65125 -14.45177 -87.98465  1.000 26.61999  ? 153 ILE   B C   1 
ATOM   3971 O O   . ILE   B 1 153 ? -111.65535 -15.01158 -88.43806  1.000 29.47310  ? 153 ILE   B O   1 
ATOM   3972 C CB  . ILE   B 1 153 ? -109.43718 -12.80569 -89.46305  1.000 23.15136  ? 153 ILE   B CB  1 
ATOM   3973 C CG1 . ILE   B 1 153 ? -109.44723 -11.36738 -89.97521  1.000 27.66168  ? 153 ILE   B CG1 1 
ATOM   3974 C CG2 . ILE   B 1 153 ? -109.82342 -13.73536 -90.59002  1.000 23.50063  ? 153 ILE   B CG2 1 
ATOM   3975 C CD1 . ILE   B 1 153 ? -108.26699 -11.05158 -90.88898  1.000 19.42187  ? 153 ILE   B CD1 1 
ATOM   3976 N N   . GLY   B 1 154 ? -109.76312 -15.10400 -87.24894  1.000 23.01127  ? 154 GLY   B N   1 
ATOM   3977 C CA  . GLY   B 1 154 ? -109.73137 -16.54933 -87.15270  1.000 17.76333  ? 154 GLY   B CA  1 
ATOM   3978 C C   . GLY   B 1 154 ? -108.54124 -17.10666 -87.91546  1.000 26.16202  ? 154 GLY   B C   1 
ATOM   3979 O O   . GLY   B 1 154 ? -107.79878 -16.38296 -88.57851  1.000 29.26980  ? 154 GLY   B O   1 
ATOM   3980 N N   . ASP   B 1 155 ? -108.37848 -18.43005 -87.83100  1.000 28.47856  ? 155 ASP   B N   1 
ATOM   3981 C CA  . ASP   B 1 155 ? -107.15684 -19.05884 -88.33870  1.000 33.32374  ? 155 ASP   B CA  1 
ATOM   3982 C C   . ASP   B 1 155 ? -107.08930 -19.11386 -89.85837  1.000 28.64811  ? 155 ASP   B C   1 
ATOM   3983 O O   . ASP   B 1 155 ? -106.04771 -19.50231 -90.39946  1.000 36.10500  ? 155 ASP   B O   1 
ATOM   3984 C CB  . ASP   B 1 155 ? -106.99827 -20.47644 -87.77364  1.000 37.01176  ? 155 ASP   B CB  1 
ATOM   3985 C CG  . ASP   B 1 155 ? -106.60113 -20.48543 -86.30184  1.000 34.96597  ? 155 ASP   B CG  1 
ATOM   3986 O OD1 . ASP   B 1 155 ? -106.41329 -19.39788 -85.71837  1.000 40.14629  ? 155 ASP   B OD1 1 
ATOM   3987 O OD2 . ASP   B 1 155 ? -106.48707 -21.58329 -85.71964  1.000 45.33955  ? 155 ASP   B OD2 1 
ATOM   3988 N N   . ASP   B 1 156 ? -108.15440 -18.74558 -90.55679  1.000 25.44289  ? 156 ASP   B N   1 
ATOM   3989 C CA  . ASP   B 1 156 ? -108.12851 -18.67900 -92.00891  1.000 30.44674  ? 156 ASP   B CA  1 
ATOM   3990 C C   . ASP   B 1 156 ? -107.69020 -17.31156 -92.51198  1.000 27.18694  ? 156 ASP   B C   1 
ATOM   3991 O O   . ASP   B 1 156 ? -107.86125 -17.01836 -93.69883  1.000 27.27225  ? 156 ASP   B O   1 
ATOM   3992 C CB  . ASP   B 1 156 ? -109.50538 -19.03612 -92.58519  1.000 25.21561  ? 156 ASP   B CB  1 
ATOM   3993 C CG  . ASP   B 1 156 ? -110.54569 -17.96090 -92.33096  1.000 32.26264  ? 156 ASP   B CG  1 
ATOM   3994 O OD1 . ASP   B 1 156 ? -110.54578 -17.36132 -91.23093  1.000 35.02331  ? 156 ASP   B OD1 1 
ATOM   3995 O OD2 . ASP   B 1 156 ? -111.36603 -17.71305 -93.24032  1.000 40.13503  ? 156 ASP   B OD2 1 
ATOM   3996 N N   . PHE   B 1 157 ? -107.12390 -16.47059 -91.63890  1.000 23.93011  ? 157 PHE   B N   1 
ATOM   3997 C CA  . PHE   B 1 157 ? -106.72907 -15.13979 -92.07675  1.000 21.18476  ? 157 PHE   B CA  1 
ATOM   3998 C C   . PHE   B 1 157 ? -105.68537 -15.21634 -93.18307  1.000 24.98226  ? 157 PHE   B C   1 
ATOM   3999 O O   . PHE   B 1 157 ? -105.69379 -14.38729 -94.10369  1.000 26.16172  ? 157 PHE   B O   1 
ATOM   4000 C CB  . PHE   B 1 157 ? -106.23983 -14.31102 -90.88427  1.000 21.80588  ? 157 PHE   B CB  1 
ATOM   4001 C CG  . PHE   B 1 157 ? -104.85089 -14.67713 -90.38672  1.000 26.83732  ? 157 PHE   B CG  1 
ATOM   4002 C CD1 . PHE   B 1 157 ? -104.65160 -15.79042 -89.57412  1.000 26.53795  ? 157 PHE   B CD1 1 
ATOM   4003 C CD2 . PHE   B 1 157 ? -103.75535 -13.88296 -90.69982  1.000 25.87899  ? 157 PHE   B CD2 1 
ATOM   4004 C CE1 . PHE   B 1 157 ? -103.37867 -16.12222 -89.11375  1.000 25.06175  ? 157 PHE   B CE1 1 
ATOM   4005 C CE2 . PHE   B 1 157 ? -102.47144 -14.20373 -90.23649  1.000 22.15561  ? 157 PHE   B CE2 1 
ATOM   4006 C CZ  . PHE   B 1 157 ? -102.28737 -15.32458 -89.44461  1.000 21.52707  ? 157 PHE   B CZ  1 
ATOM   4007 N N   . MET   B 1 158 ? -104.82752 -16.23908 -93.15050  1.000 23.11400  ? 158 MET   B N   1 
ATOM   4008 C CA  . MET   B 1 158 ? -103.79725 -16.36818 -94.17301  1.000 21.62539  ? 158 MET   B CA  1 
ATOM   4009 C C   . MET   B 1 158 ? -104.39224 -16.71431 -95.53321  1.000 24.56102  ? 158 MET   B C   1 
ATOM   4010 O O   . MET   B 1 158 ? -103.97756 -16.14522 -96.55306  1.000 26.04443  ? 158 MET   B O   1 
ATOM   4011 C CB  . MET   B 1 158 ? -102.76137 -17.40468 -93.74634  1.000 18.02953  ? 158 MET   B CB  1 
ATOM   4012 C CG  . MET   B 1 158 ? -101.86126 -16.91941 -92.61289  1.000 26.40036  ? 158 MET   B CG  1 
ATOM   4013 S SD  . MET   B 1 158 ? -100.76566 -18.19659 -91.94845  1.000 26.60749  ? 158 MET   B SD  1 
ATOM   4014 C CE  . MET   B 1 158 ? -101.94245 -19.18376 -91.02518  1.000 29.69830  ? 158 MET   B CE  1 
ATOM   4015 N N   . GLU   B 1 159 ? -105.35969 -17.63787 -95.57958  1.000 21.56397  ? 159 GLU   B N   1 
ATOM   4016 C CA  . GLU   B 1 159 ? -106.02024 -17.93538 -96.85066  1.000 24.80966  ? 159 GLU   B CA  1 
ATOM   4017 C C   . GLU   B 1 159 ? -106.63339 -16.67724 -97.44210  1.000 27.46087  ? 159 GLU   B C   1 
ATOM   4018 O O   . GLU   B 1 159 ? -106.49500 -16.40253 -98.64256  1.000 22.55953  ? 159 GLU   B O   1 
ATOM   4019 C CB  . GLU   B 1 159 ? -107.10735 -18.99507 -96.67578  1.000 24.65384  ? 159 GLU   B CB  1 
ATOM   4020 C CG  . GLU   B 1 159 ? -106.86089 -20.00709 -95.59428  1.000 36.92827  ? 159 GLU   B CG  1 
ATOM   4021 C CD  . GLU   B 1 159 ? -107.95712 -21.06159 -95.53431  1.000 44.49192  ? 159 GLU   B CD  1 
ATOM   4022 O OE1 . GLU   B 1 159 ? -108.89901 -21.01441 -96.36569  1.000 31.75745  ? 159 GLU   B OE1 1 
ATOM   4023 O OE2 . GLU   B 1 159 ? -107.86333 -21.93809 -94.65287  1.000 36.96882  ? 159 GLU   B OE2 1 
ATOM   4024 N N   . GLN   B 1 160 ? -107.33012 -15.90477 -96.60657  1.000 24.79106  ? 160 GLN   B N   1 
ATOM   4025 C CA  . GLN   B 1 160 ? -107.94514 -14.67114 -97.07957  1.000 22.30052  ? 160 GLN   B CA  1 
ATOM   4026 C C   . GLN   B 1 160 ? -106.89726 -13.73398 -97.66985  1.000 26.28037  ? 160 GLN   B C   1 
ATOM   4027 O O   . GLN   B 1 160 ? -107.06706 -13.21285 -98.78134  1.000 21.90601  ? 160 GLN   B O   1 
ATOM   4028 C CB  . GLN   B 1 160 ? -108.70114 -14.00290 -95.93045  1.000 25.38673  ? 160 GLN   B CB  1 
ATOM   4029 C CG  . GLN   B 1 160 ? -109.84733 -14.84926 -95.39280  1.000 31.40176  ? 160 GLN   B CG  1 
ATOM   4030 C CD  . GLN   B 1 160 ? -110.79315 -15.26247 -96.49642  1.000 31.45352  ? 160 GLN   B CD  1 
ATOM   4031 O OE1 . GLN   B 1 160 ? -111.32545 -14.41899 -97.21671  1.000 30.16302  ? 160 GLN   B OE1 1 
ATOM   4032 N NE2 . GLN   B 1 160 ? -110.98061 -16.56036 -96.65952  1.000 34.96028  ? 160 GLN   B NE2 1 
ATOM   4033 N N   . ALA   B 1 161 ? -105.78584 -13.52983 -96.95015  1.000 20.04432  ? 161 ALA   B N   1 
ATOM   4034 C CA  . ALA   B 1 161 ? -104.76287 -12.61938 -97.44909  1.000 15.92689  ? 161 ALA   B CA  1 
ATOM   4035 C C   . ALA   B 1 161 ? -104.22097 -13.09071 -98.79844  1.000 20.74127  ? 161 ALA   B C   1 
ATOM   4036 O O   . ALA   B 1 161 ? -104.05478 -12.28496 -99.72586  1.000 19.22566  ? 161 ALA   B O   1 
ATOM   4037 C CB  . ALA   B 1 161 ? -103.64901 -12.46915 -96.41543  1.000 10.95507  ? 161 ALA   B CB  1 
ATOM   4038 N N   . PHE   B 1 162 ? -103.98008 -14.39747 -98.94517  1.000 18.27402  ? 162 PHE   B N   1 
ATOM   4039 C CA  . PHE   B 1 162 ? -103.46174 -14.90199 -100.21486 1.000 21.23148  ? 162 PHE   B CA  1 
ATOM   4040 C C   . PHE   B 1 162 ? -104.47824 -14.72109 -101.33647 1.000 21.46091  ? 162 PHE   B C   1 
ATOM   4041 O O   . PHE   B 1 162 ? -104.11358 -14.34163 -102.45495 1.000 23.54525  ? 162 PHE   B O   1 
ATOM   4042 C CB  . PHE   B 1 162 ? -103.05286 -16.37102 -100.07754 1.000 14.28611  ? 162 PHE   B CB  1 
ATOM   4043 C CG  . PHE   B 1 162 ? -101.62947 -16.56419 -99.59785  1.000 23.58792  ? 162 PHE   B CG  1 
ATOM   4044 C CD1 . PHE   B 1 162 ? -100.55328 -16.36805 -100.46226 1.000 26.34051  ? 162 PHE   B CD1 1 
ATOM   4045 C CD2 . PHE   B 1 162 ? -101.36368 -16.93262 -98.28063  1.000 18.60862  ? 162 PHE   B CD2 1 
ATOM   4046 C CE1 . PHE   B 1 162 ? -99.25269  -16.53270 -100.02487 1.000 19.09809  ? 162 PHE   B CE1 1 
ATOM   4047 C CE2 . PHE   B 1 162 ? -100.06559 -17.09863 -97.83686  1.000 21.48896  ? 162 PHE   B CE2 1 
ATOM   4048 C CZ  . PHE   B 1 162 ? -99.00722  -16.89823 -98.70455  1.000 24.13838  ? 162 PHE   B CZ  1 
ATOM   4049 N N   . LEU   B 1 163 ? -105.75888 -14.97313 -101.05672 1.000 22.41594  ? 163 LEU   B N   1 
ATOM   4050 C CA  . LEU   B 1 163 ? -106.78235 -14.81482 -102.08834 1.000 23.18850  ? 163 LEU   B CA  1 
ATOM   4051 C C   . LEU   B 1 163 ? -106.89263 -13.36308 -102.52094 1.000 20.01447  ? 163 LEU   B C   1 
ATOM   4052 O O   . LEU   B 1 163 ? -106.95453 -13.06289 -103.71827 1.000 26.09747  ? 163 LEU   B O   1 
ATOM   4053 C CB  . LEU   B 1 163 ? -108.13310 -15.31931 -101.57856 1.000 19.86860  ? 163 LEU   B CB  1 
ATOM   4054 C CG  . LEU   B 1 163 ? -108.23166 -16.82644 -101.36269 1.000 25.42444  ? 163 LEU   B CG  1 
ATOM   4055 C CD1 . LEU   B 1 163 ? -109.40897 -17.15137 -100.44323 1.000 17.00204  ? 163 LEU   B CD1 1 
ATOM   4056 C CD2 . LEU   B 1 163 ? -108.34677 -17.56518 -102.70503 1.000 21.34468  ? 163 LEU   B CD2 1 
ATOM   4057 N N   . TYR   B 1 164 ? -106.91356 -12.44727 -101.55080 1.000 18.19325  ? 164 TYR   B N   1 
ATOM   4058 C CA  . TYR   B 1 164 ? -106.96357 -11.02353 -101.86533 1.000 23.56043  ? 164 TYR   B CA  1 
ATOM   4059 C C   . TYR   B 1 164 ? -105.76748 -10.59665 -102.70273 1.000 21.30944  ? 164 TYR   B C   1 
ATOM   4060 O O   . TYR   B 1 164 ? -105.91569 -9.81843  -103.65405 1.000 27.24496  ? 164 TYR   B O   1 
ATOM   4061 C CB  . TYR   B 1 164 ? -107.01387 -10.19872 -100.58134 1.000 23.33899  ? 164 TYR   B CB  1 
ATOM   4062 C CG  . TYR   B 1 164 ? -108.23859 -10.42381 -99.75228  1.000 25.09833  ? 164 TYR   B CG  1 
ATOM   4063 C CD1 . TYR   B 1 164 ? -109.42963 -10.83813 -100.33695 1.000 23.51809  ? 164 TYR   B CD1 1 
ATOM   4064 C CD2 . TYR   B 1 164 ? -108.21340 -10.21362 -98.37897  1.000 18.59425  ? 164 TYR   B CD2 1 
ATOM   4065 C CE1 . TYR   B 1 164 ? -110.56938 -11.03694 -99.56771  1.000 28.76084  ? 164 TYR   B CE1 1 
ATOM   4066 C CE2 . TYR   B 1 164 ? -109.33726 -10.41392 -97.60742  1.000 22.61088  ? 164 TYR   B CE2 1 
ATOM   4067 C CZ  . TYR   B 1 164 ? -110.51512 -10.82697 -98.20159  1.000 28.97517  ? 164 TYR   B CZ  1 
ATOM   4068 O OH  . TYR   B 1 164 ? -111.63689 -11.02174 -97.42497  1.000 31.04650  ? 164 TYR   B OH  1 
ATOM   4069 N N   . ALA   B 1 165 ? -104.57019 -11.07937 -102.35834 1.000 18.59919  ? 165 ALA   B N   1 
ATOM   4070 C CA  . ALA   B 1 165 ? -103.39239 -10.73867 -103.15169 1.000 20.81808  ? 165 ALA   B CA  1 
ATOM   4071 C C   . ALA   B 1 165 ? -103.52667 -11.27554 -104.57171 1.000 23.66644  ? 165 ALA   B C   1 
ATOM   4072 O O   . ALA   B 1 165 ? -103.29349 -10.54805 -105.54927 1.000 18.39832  ? 165 ALA   B O   1 
ATOM   4073 C CB  . ALA   B 1 165 ? -102.12364 -11.27895 -102.48502 1.000 18.34309  ? 165 ALA   B CB  1 
ATOM   4074 N N   . TYR   B 1 166 ? -103.92228 -12.55016 -104.69783 1.000 21.79335  ? 166 TYR   B N   1 
ATOM   4075 C CA  . TYR   B 1 166 ? -104.06071 -13.17660 -106.01127 1.000 29.63883  ? 166 TYR   B CA  1 
ATOM   4076 C C   . TYR   B 1 166 ? -105.02187 -12.39251 -106.89145 1.000 26.68975  ? 166 TYR   B C   1 
ATOM   4077 O O   . TYR   B 1 166 ? -104.71427 -12.08999 -108.04905 1.000 24.41629  ? 166 TYR   B O   1 
ATOM   4078 C CB  . TYR   B 1 166 ? -104.53507 -14.61898 -105.84794 1.000 25.15273  ? 166 TYR   B CB  1 
ATOM   4079 C CG  . TYR   B 1 166 ? -104.74328 -15.36926 -107.13853 1.000 25.90325  ? 166 TYR   B CG  1 
ATOM   4080 C CD1 . TYR   B 1 166 ? -103.66198 -15.77831 -107.91785 1.000 34.22620  ? 166 TYR   B CD1 1 
ATOM   4081 C CD2 . TYR   B 1 166 ? -106.02169 -15.69176 -107.57635 1.000 31.03099  ? 166 TYR   B CD2 1 
ATOM   4082 C CE1 . TYR   B 1 166 ? -103.85500 -16.48676 -109.10660 1.000 30.24433  ? 166 TYR   B CE1 1 
ATOM   4083 C CE2 . TYR   B 1 166 ? -106.22199 -16.38828 -108.76561 1.000 25.68698  ? 166 TYR   B CE2 1 
ATOM   4084 C CZ  . TYR   B 1 166 ? -105.14194 -16.78687 -109.51993 1.000 30.69684  ? 166 TYR   B CZ  1 
ATOM   4085 O OH  . TYR   B 1 166 ? -105.35579 -17.48174 -110.69134 1.000 33.04464  ? 166 TYR   B OH  1 
ATOM   4086 N N   . GLU   B 1 167 ? -106.17825 -12.01806 -106.33613 1.000 27.69203  ? 167 GLU   B N   1 
ATOM   4087 C CA  . GLU   B 1 167 ? -107.17018 -11.27882 -107.10408 1.000 25.40743  ? 167 GLU   B CA  1 
ATOM   4088 C C   . GLU   B 1 167 ? -106.63673 -9.92327  -107.55491 1.000 30.56156  ? 167 GLU   B C   1 
ATOM   4089 O O   . GLU   B 1 167 ? -106.99317 -9.45029  -108.64527 1.000 27.65492  ? 167 GLU   B O   1 
ATOM   4090 C CB  . GLU   B 1 167 ? -108.44836 -11.13062 -106.27758 1.000 21.74988  ? 167 GLU   B CB  1 
ATOM   4091 C CG  . GLU   B 1 167 ? -109.19551 -9.81296  -106.48024 1.000 32.32091  ? 167 GLU   B CG  1 
ATOM   4092 C CD  . GLU   B 1 167 ? -110.51705 -9.75149  -105.71262 1.000 50.81605  ? 167 GLU   B CD  1 
ATOM   4093 O OE1 . GLU   B 1 167 ? -111.44611 -10.52657 -106.03701 1.000 51.70022  ? 167 GLU   B OE1 1 
ATOM   4094 O OE2 . GLU   B 1 167 ? -110.62526 -8.92457  -104.77920 1.000 55.20721  ? 167 GLU   B OE2 1 
ATOM   4095 N N   . ALA   B 1 168 ? -105.75592 -9.30205  -106.75876 1.000 23.80943  ? 168 ALA   B N   1 
ATOM   4096 C CA  . ALA   B 1 168 ? -105.23023 -7.98885  -107.13032 1.000 26.84126  ? 168 ALA   B CA  1 
ATOM   4097 C C   . ALA   B 1 168 ? -104.20239 -8.09435  -108.24976 1.000 24.71759  ? 168 ALA   B C   1 
ATOM   4098 O O   . ALA   B 1 168 ? -104.12774 -7.21102  -109.10693 1.000 26.63360  ? 168 ALA   B O   1 
ATOM   4099 C CB  . ALA   B 1 168 ? -104.62309 -7.28780  -105.91714 1.000 18.92873  ? 168 ALA   B CB  1 
ATOM   4100 N N   . ASP   B 1 169 ? -103.40236 -9.15992  -108.25927 1.000 24.98182  ? 169 ASP   B N   1 
ATOM   4101 C CA  . ASP   B 1 169 ? -102.44582 -9.40412  -109.34202 1.000 28.26449  ? 169 ASP   B CA  1 
ATOM   4102 C C   . ASP   B 1 169 ? -102.27536 -10.90046 -109.53142 1.000 27.27618  ? 169 ASP   B C   1 
ATOM   4103 O O   . ASP   B 1 169 ? -101.40984 -11.52574 -108.90429 1.000 26.76193  ? 169 ASP   B O   1 
ATOM   4104 C CB  . ASP   B 1 169 ? -101.09286 -8.75345  -109.06932 1.000 22.22985  ? 169 ASP   B CB  1 
ATOM   4105 C CG  . ASP   B 1 169 ? -100.14013 -8.90255  -110.23493 1.000 24.27469  ? 169 ASP   B CG  1 
ATOM   4106 O OD1 . ASP   B 1 169 ? -100.50672 -9.54368  -111.24338 1.000 30.64256  ? 169 ASP   B OD1 1 
ATOM   4107 O OD2 . ASP   B 1 169 ? -99.02307  -8.37202  -110.15307 1.000 24.77007  ? 169 ASP   B OD2 1 
ATOM   4108 N N   . PRO   B 1 170 ? -103.07119 -11.51046 -110.41593 1.000 28.95275  ? 170 PRO   B N   1 
ATOM   4109 C CA  . PRO   B 1 170 ? -102.96406 -12.96698 -110.62793 1.000 23.82662  ? 170 PRO   B CA  1 
ATOM   4110 C C   . PRO   B 1 170 ? -101.63751 -13.40829 -111.21983 1.000 20.59512  ? 170 PRO   B C   1 
ATOM   4111 O O   . PRO   B 1 170 ? -101.39544 -14.62284 -111.29991 1.000 24.07602  ? 170 PRO   B O   1 
ATOM   4112 C CB  . PRO   B 1 170 ? -104.11914 -13.27109 -111.59290 1.000 28.35121  ? 170 PRO   B CB  1 
ATOM   4113 C CG  . PRO   B 1 170 ? -105.06256 -12.11469 -111.45115 1.000 30.02415  ? 170 PRO   B CG  1 
ATOM   4114 C CD  . PRO   B 1 170 ? -104.18893 -10.92009 -111.16994 1.000 27.07130  ? 170 PRO   B CD  1 
ATOM   4115 N N   . ASP   B 1 171 ? -100.78122 -12.47661 -111.64989 1.000 20.94002  ? 171 ASP   B N   1 
ATOM   4116 C CA  . ASP   B 1 171 ? -99.46358  -12.82791 -112.17574 1.000 28.36581  ? 171 ASP   B CA  1 
ATOM   4117 C C   . ASP   B 1 171 ? -98.36546  -12.81186 -111.12533 1.000 23.65677  ? 171 ASP   B C   1 
ATOM   4118 O O   . ASP   B 1 171 ? -97.26802  -13.31099 -111.39486 1.000 28.69333  ? 171 ASP   B O   1 
ATOM   4119 C CB  . ASP   B 1 171 ? -99.06506  -11.87973 -113.30695 1.000 29.37581  ? 171 ASP   B CB  1 
ATOM   4120 C CG  . ASP   B 1 171 ? -100.02508 -11.94157 -114.47877 1.000 32.73609  ? 171 ASP   B CG  1 
ATOM   4121 O OD1 . ASP   B 1 171 ? -100.61832 -13.02118 -114.72980 1.000 28.97584  ? 171 ASP   B OD1 1 
ATOM   4122 O OD2 . ASP   B 1 171 ? -100.18469 -10.90157 -115.14218 1.000 37.01358  ? 171 ASP   B OD2 1 
ATOM   4123 N N   . ALA   B 1 172 ? -98.61283  -12.24616 -109.94717 1.000 24.06343  ? 172 ALA   B N   1 
ATOM   4124 C CA  . ALA   B 1 172 ? -97.56281  -12.16544 -108.94352 1.000 27.41854  ? 172 ALA   B CA  1 
ATOM   4125 C C   . ALA   B 1 172 ? -97.38423  -13.51681 -108.26618 1.000 24.80103  ? 172 ALA   B C   1 
ATOM   4126 O O   . ALA   B 1 172 ? -98.35562  -14.24591 -108.03227 1.000 22.83915  ? 172 ALA   B O   1 
ATOM   4127 C CB  . ALA   B 1 172 ? -97.88101  -11.08596 -107.91213 1.000 19.43328  ? 172 ALA   B CB  1 
ATOM   4128 N N   . LEU   B 1 173 ? -96.12763  -13.86580 -107.99707 1.000 16.88484  ? 173 LEU   B N   1 
ATOM   4129 C CA  . LEU   B 1 173 ? -95.81968  -15.01798 -107.16281 1.000 20.16747  ? 173 LEU   B CA  1 
ATOM   4130 C C   . LEU   B 1 173 ? -96.02407  -14.65870 -105.69262 1.000 19.43557  ? 173 LEU   B C   1 
ATOM   4131 O O   . LEU   B 1 173 ? -95.47396  -13.66657 -105.20535 1.000 21.12742  ? 173 LEU   B O   1 
ATOM   4132 C CB  . LEU   B 1 173 ? -94.38548  -15.48411 -107.40689 1.000 19.44725  ? 173 LEU   B CB  1 
ATOM   4133 C CG  . LEU   B 1 173 ? -94.09973  -16.07463 -108.79186 1.000 19.35740  ? 173 LEU   B CG  1 
ATOM   4134 C CD1 . LEU   B 1 173 ? -92.63099  -16.43131 -108.90510 1.000 19.83861  ? 173 LEU   B CD1 1 
ATOM   4135 C CD2 . LEU   B 1 173 ? -94.94531  -17.29544 -109.04451 1.000 22.29493  ? 173 LEU   B CD2 1 
ATOM   4136 N N   . LEU   B 1 174 ? -96.81711  -15.46147 -104.98504 1.000 18.04096  ? 174 LEU   B N   1 
ATOM   4137 C CA  . LEU   B 1 174 ? -97.21190  -15.17213 -103.61312 1.000 18.99354  ? 174 LEU   B CA  1 
ATOM   4138 C C   . LEU   B 1 174 ? -96.47334  -16.09885 -102.65568 1.000 27.99071  ? 174 LEU   B C   1 
ATOM   4139 O O   . LEU   B 1 174 ? -96.43900  -17.31674 -102.87533 1.000 25.92420  ? 174 LEU   B O   1 
ATOM   4140 C CB  . LEU   B 1 174 ? -98.72139  -15.32024 -103.45258 1.000 18.25281  ? 174 LEU   B CB  1 
ATOM   4141 C CG  . LEU   B 1 174 ? -99.50515  -14.44879 -104.43289 1.000 20.97143  ? 174 LEU   B CG  1 
ATOM   4142 C CD1 . LEU   B 1 174 ? -101.01070 -14.58898 -104.21473 1.000 17.06070  ? 174 LEU   B CD1 1 
ATOM   4143 C CD2 . LEU   B 1 174 ? -99.06678  -13.01364 -104.29151 1.000 14.12084  ? 174 LEU   B CD2 1 
ATOM   4144 N N   . PHE   B 1 175 ? -95.90180  -15.52158 -101.58527 1.000 22.37684  ? 175 PHE   B N   1 
ATOM   4145 C CA  . PHE   B 1 175 ? -94.98155  -16.21829 -100.68930 1.000 20.42043  ? 175 PHE   B CA  1 
ATOM   4146 C C   . PHE   B 1 175 ? -95.44690  -16.16697 -99.24626  1.000 16.66952  ? 175 PHE   B C   1 
ATOM   4147 O O   . PHE   B 1 175 ? -95.95826  -15.13877 -98.78641  1.000 14.36758  ? 175 PHE   B O   1 
ATOM   4148 C CB  . PHE   B 1 175 ? -93.57783  -15.60121 -100.71255 1.000 19.07233  ? 175 PHE   B CB  1 
ATOM   4149 C CG  . PHE   B 1 175 ? -92.75035  -15.98731 -101.89004 1.000 24.73648  ? 175 PHE   B CG  1 
ATOM   4150 C CD1 . PHE   B 1 175 ? -93.03186  -15.46536 -103.15433 1.000 17.03305  ? 175 PHE   B CD1 1 
ATOM   4151 C CD2 . PHE   B 1 175 ? -91.66572  -16.83888 -101.73359 1.000 14.56472  ? 175 PHE   B CD2 1 
ATOM   4152 C CE1 . PHE   B 1 175 ? -92.25403  -15.79924 -104.24312 1.000 19.53609  ? 175 PHE   B CE1 1 
ATOM   4153 C CE2 . PHE   B 1 175 ? -90.88893  -17.18266 -102.81739 1.000 21.96742  ? 175 PHE   B CE2 1 
ATOM   4154 C CZ  . PHE   B 1 175 ? -91.17457  -16.65445 -104.07763 1.000 22.94724  ? 175 PHE   B CZ  1 
ATOM   4155 N N   . TYR   B 1 176 ? -95.19926  -17.26747 -98.53114  1.000 18.66504  ? 176 TYR   B N   1 
ATOM   4156 C CA  . TYR   B 1 176 ? -95.10073  -17.26708 -97.07553  1.000 15.27782  ? 176 TYR   B CA  1 
ATOM   4157 C C   . TYR   B 1 176 ? -93.62951  -17.12102 -96.69357  1.000 17.38813  ? 176 TYR   B C   1 
ATOM   4158 O O   . TYR   B 1 176 ? -92.78290  -17.87169 -97.19011  1.000 15.70299  ? 176 TYR   B O   1 
ATOM   4159 C CB  . TYR   B 1 176 ? -95.67004  -18.55747 -96.46876  1.000 15.91035  ? 176 TYR   B CB  1 
ATOM   4160 C CG  . TYR   B 1 176 ? -95.48849  -18.58257 -94.96325  1.000 18.56683  ? 176 TYR   B CG  1 
ATOM   4161 C CD1 . TYR   B 1 176 ? -96.46465  -18.05794 -94.12489  1.000 16.17526  ? 176 TYR   B CD1 1 
ATOM   4162 C CD2 . TYR   B 1 176 ? -94.30821  -19.06511 -94.38075  1.000 11.66475  ? 176 TYR   B CD2 1 
ATOM   4163 C CE1 . TYR   B 1 176 ? -96.29244  -18.02902 -92.74507  1.000 17.15360  ? 176 TYR   B CE1 1 
ATOM   4164 C CE2 . TYR   B 1 176 ? -94.12548  -19.03046 -93.00160  1.000 18.31435  ? 176 TYR   B CE2 1 
ATOM   4165 C CZ  . TYR   B 1 176 ? -95.12265  -18.51232 -92.18855  1.000 20.83569  ? 176 TYR   B CZ  1 
ATOM   4166 O OH  . TYR   B 1 176 ? -94.96484  -18.48579 -90.81489  1.000 21.19509  ? 176 TYR   B OH  1 
ATOM   4167 N N   . ASN   B 1 177 ? -93.33232  -16.18930 -95.78412  1.000 13.77468  ? 177 ASN   B N   1 
ATOM   4168 C CA  . ASN   B 1 177 ? -91.96055  -15.81018 -95.45415  1.000 14.52392  ? 177 ASN   B CA  1 
ATOM   4169 C C   . ASN   B 1 177 ? -91.73698  -15.92605 -93.94689  1.000 19.66960  ? 177 ASN   B C   1 
ATOM   4170 O O   . ASN   B 1 177 ? -92.58840  -15.50584 -93.16101  1.000 16.78991  ? 177 ASN   B O   1 
ATOM   4171 C CB  . ASN   B 1 177 ? -91.68125  -14.37701 -95.93880  1.000 12.96467  ? 177 ASN   B CB  1 
ATOM   4172 C CG  . ASN   B 1 177 ? -90.20517  -13.97597 -95.82632  1.000 18.41605  ? 177 ASN   B CG  1 
ATOM   4173 O OD1 . ASN   B 1 177 ? -89.32637  -14.61704 -96.40789  1.000 15.72533  ? 177 ASN   B OD1 1 
ATOM   4174 N ND2 . ASN   B 1 177 ? -89.93801  -12.88788 -95.09887  1.000 11.85014  ? 177 ASN   B ND2 1 
ATOM   4175 N N   . ASP   B 1 178 ? -90.59066  -16.48462 -93.54044  1.000 17.32500  ? 178 ASP   B N   1 
ATOM   4176 C CA  . ASP   B 1 178 ? -90.34315  -16.74568 -92.12229  1.000 19.47413  ? 178 ASP   B CA  1 
ATOM   4177 C C   . ASP   B 1 178 ? -88.84628  -16.93916 -91.86310  1.000 21.68110  ? 178 ASP   B C   1 
ATOM   4178 O O   . ASP   B 1 178 ? -88.05723  -17.18834 -92.78436  1.000 20.34305  ? 178 ASP   B O   1 
ATOM   4179 C CB  . ASP   B 1 178 ? -91.14276  -17.97084 -91.64288  1.000 16.61927  ? 178 ASP   B CB  1 
ATOM   4180 C CG  . ASP   B 1 178 ? -91.67232  -17.81969 -90.20674  1.000 24.62697  ? 178 ASP   B CG  1 
ATOM   4181 O OD1 . ASP   B 1 178 ? -91.06657  -17.07184 -89.40922  1.000 17.54074  ? 178 ASP   B OD1 1 
ATOM   4182 O OD2 . ASP   B 1 178 ? -92.68567  -18.47315 -89.86348  1.000 20.29478  ? 178 ASP   B OD2 1 
ATOM   4183 N N   . TYR   B 1 179 ? -88.46942  -16.80766 -90.58931  1.000 15.16133  ? 179 TYR   B N   1 
ATOM   4184 C CA  . TYR   B 1 179 ? -87.10348  -16.97187 -90.10371  1.000 18.90201  ? 179 TYR   B CA  1 
ATOM   4185 C C   . TYR   B 1 179 ? -86.99806  -18.23585 -89.25323  1.000 19.17427  ? 179 TYR   B C   1 
ATOM   4186 O O   . TYR   B 1 179 ? -87.99773  -18.88618 -88.93565  1.000 16.52761  ? 179 TYR   B O   1 
ATOM   4187 C CB  . TYR   B 1 179 ? -86.65481  -15.75415 -89.28221  1.000 18.03165  ? 179 TYR   B CB  1 
ATOM   4188 C CG  . TYR   B 1 179 ? -87.49579  -15.55813 -88.03986  1.000 23.04925  ? 179 TYR   B CG  1 
ATOM   4189 C CD1 . TYR   B 1 179 ? -88.69380  -14.85887 -88.09315  1.000 16.10009  ? 179 TYR   B CD1 1 
ATOM   4190 C CD2 . TYR   B 1 179 ? -87.10763  -16.09112 -86.82139  1.000 24.26587  ? 179 TYR   B CD2 1 
ATOM   4191 C CE1 . TYR   B 1 179 ? -89.47359  -14.69295 -86.96909  1.000 23.22492  ? 179 TYR   B CE1 1 
ATOM   4192 C CE2 . TYR   B 1 179 ? -87.88969  -15.93406 -85.68966  1.000 19.22868  ? 179 TYR   B CE2 1 
ATOM   4193 C CZ  . TYR   B 1 179 ? -89.06837  -15.23820 -85.77302  1.000 22.13779  ? 179 TYR   B CZ  1 
ATOM   4194 O OH  . TYR   B 1 179 ? -89.84490  -15.07368 -84.65918  1.000 17.23322  ? 179 TYR   B OH  1 
ATOM   4195 N N   . ASN   B 1 180 ? -85.75962  -18.57008 -88.87756  1.000 16.34293  ? 180 ASN   B N   1 
ATOM   4196 C CA  . ASN   B 1 180 ? -85.44552  -19.83578 -88.20113  1.000 22.44617  ? 180 ASN   B CA  1 
ATOM   4197 C C   . ASN   B 1 180 ? -86.05589  -21.00965 -88.95388  1.000 21.28675  ? 180 ASN   B C   1 
ATOM   4198 O O   . ASN   B 1 180 ? -86.47648  -22.01488 -88.37308  1.000 21.12065  ? 180 ASN   B O   1 
ATOM   4199 C CB  . ASN   B 1 180 ? -85.88850  -19.81785 -86.73782  1.000 23.48423  ? 180 ASN   B CB  1 
ATOM   4200 C CG  . ASN   B 1 180 ? -84.98104  -18.95818 -85.88224  1.000 22.36886  ? 180 ASN   B CG  1 
ATOM   4201 O OD1 . ASN   B 1 180 ? -83.89185  -18.59140 -86.31593  1.000 23.52485  ? 180 ASN   B OD1 1 
ATOM   4202 N ND2 . ASN   B 1 180 ? -85.41902  -18.62940 -84.67086  1.000 26.81016  ? 180 ASN   B ND2 1 
ATOM   4203 N N   . GLU   B 1 181 ? -86.07578  -20.87345 -90.27565  1.000 16.10439  ? 181 GLU   B N   1 
ATOM   4204 C CA  . GLU   B 1 181 ? -86.74814  -21.79685 -91.17056  1.000 20.52410  ? 181 GLU   B CA  1 
ATOM   4205 C C   . GLU   B 1 181 ? -86.03653  -23.14892 -91.29274  1.000 25.84421  ? 181 GLU   B C   1 
ATOM   4206 O O   . GLU   B 1 181 ? -86.59998  -24.07439 -91.89075  1.000 27.21080  ? 181 GLU   B O   1 
ATOM   4207 C CB  . GLU   B 1 181 ? -86.89163  -21.12068 -92.54591  1.000 14.24667  ? 181 GLU   B CB  1 
ATOM   4208 C CG  . GLU   B 1 181 ? -85.56195  -20.89089 -93.29518  1.000 21.66309  ? 181 GLU   B CG  1 
ATOM   4209 C CD  . GLU   B 1 181 ? -84.55451  -19.98614 -92.55988  1.000 21.21188  ? 181 GLU   B CD  1 
ATOM   4210 O OE1 . GLU   B 1 181 ? -84.91231  -18.85059 -92.19763  1.000 21.96201  ? 181 GLU   B OE1 1 
ATOM   4211 O OE2 . GLU   B 1 181 ? -83.39463  -20.40749 -92.35643  1.000 23.75602  ? 181 GLU   B OE2 1 
ATOM   4212 N N   . CYS   B 1 182 ? -84.83169  -23.29775 -90.74442  1.000 18.98854  ? 182 CYS   B N   1 
ATOM   4213 C CA  . CYS   B 1 182 ? -84.08748  -24.54797 -90.84908  1.000 24.32990  ? 182 CYS   B CA  1 
ATOM   4214 C C   . CYS   B 1 182 ? -83.97608  -25.29347 -89.53150  1.000 24.98847  ? 182 CYS   B C   1 
ATOM   4215 O O   . CYS   B 1 182 ? -83.42640  -26.39728 -89.50636  1.000 28.71020  ? 182 CYS   B O   1 
ATOM   4216 C CB  . CYS   B 1 182 ? -82.68717  -24.28079 -91.42126  1.000 17.15353  ? 182 CYS   B CB  1 
ATOM   4217 S SG  . CYS   B 1 182 ? -82.77899  -23.59021 -93.07174  1.000 18.10769  ? 182 CYS   B SG  1 
ATOM   4218 N N   . PHE   B 1 183 ? -84.46219  -24.72755 -88.44832  1.000 19.37960  ? 183 PHE   B N   1 
ATOM   4219 C CA  . PHE   B 1 183 ? -84.51863  -25.47727 -87.20799  1.000 24.28049  ? 183 PHE   B CA  1 
ATOM   4220 C C   . PHE   B 1 183 ? -85.64145  -26.49016 -87.33908  1.000 34.61321  ? 183 PHE   B C   1 
ATOM   4221 O O   . PHE   B 1 183 ? -86.77797  -26.10196 -87.64582  1.000 32.45973  ? 183 PHE   B O   1 
ATOM   4222 C CB  . PHE   B 1 183 ? -84.72745  -24.54879 -86.02546  1.000 21.30303  ? 183 PHE   B CB  1 
ATOM   4223 C CG  . PHE   B 1 183 ? -83.56981  -23.62914 -85.79713  1.000 39.04078  ? 183 PHE   B CG  1 
ATOM   4224 C CD1 . PHE   B 1 183 ? -82.27370  -24.06051 -86.06845  1.000 44.59362  ? 183 PHE   B CD1 1 
ATOM   4225 C CD2 . PHE   B 1 183 ? -83.75756  -22.34155 -85.33280  1.000 36.09088  ? 183 PHE   B CD2 1 
ATOM   4226 C CE1 . PHE   B 1 183 ? -81.19256  -23.22791 -85.86753  1.000 46.59369  ? 183 PHE   B CE1 1 
ATOM   4227 C CE2 . PHE   B 1 183 ? -82.66844  -21.49906 -85.12899  1.000 40.06478  ? 183 PHE   B CE2 1 
ATOM   4228 C CZ  . PHE   B 1 183 ? -81.39276  -21.94036 -85.39872  1.000 40.32217  ? 183 PHE   B CZ  1 
ATOM   4229 N N   . PRO   B 1 184 ? -85.36927  -27.78431 -87.14829  1.000 36.35051  ? 184 PRO   B N   1 
ATOM   4230 C CA  . PRO   B 1 184 ? -86.32405  -28.82163 -87.59173  1.000 26.89226  ? 184 PRO   B CA  1 
ATOM   4231 C C   . PRO   B 1 184 ? -87.74656  -28.64557 -87.06881  1.000 29.33067  ? 184 PRO   B C   1 
ATOM   4232 O O   . PRO   B 1 184 ? -88.70860  -28.80607 -87.83581  1.000 28.04238  ? 184 PRO   B O   1 
ATOM   4233 C CB  . PRO   B 1 184 ? -85.67555  -30.11056 -87.07470  1.000 25.65075  ? 184 PRO   B CB  1 
ATOM   4234 C CG  . PRO   B 1 184 ? -84.18599  -29.79017 -87.03961  1.000 25.22130  ? 184 PRO   B CG  1 
ATOM   4235 C CD  . PRO   B 1 184 ? -84.10676  -28.34720 -86.62882  1.000 22.58285  ? 184 PRO   B CD  1 
ATOM   4236 N N   . GLU   B 1 185 ? -87.91018  -28.31566 -85.78607  1.000 23.51035  ? 185 GLU   B N   1 
ATOM   4237 C CA  . GLU   B 1 185 ? -89.25539  -28.16236 -85.23937  1.000 30.15849  ? 185 GLU   B CA  1 
ATOM   4238 C C   . GLU   B 1 185 ? -90.01627  -27.04746 -85.95104  1.000 27.12260  ? 185 GLU   B C   1 
ATOM   4239 O O   . GLU   B 1 185 ? -91.18928  -27.21588 -86.30501  1.000 30.18514  ? 185 GLU   B O   1 
ATOM   4240 C CB  . GLU   B 1 185 ? -89.19358  -27.90018 -83.73199  1.000 28.46608  ? 185 GLU   B CB  1 
ATOM   4241 C CG  . GLU   B 1 185 ? -90.54708  -27.56139 -83.12116  1.000 51.77779  ? 185 GLU   B CG  1 
ATOM   4242 C CD  . GLU   B 1 185 ? -90.52188  -27.44330 -81.59963  1.000 64.22605  ? 185 GLU   B CD  1 
ATOM   4243 O OE1 . GLU   B 1 185 ? -89.42275  -27.25121 -81.02945  1.000 58.81701  ? 185 GLU   B OE1 1 
ATOM   4244 O OE2 . GLU   B 1 185 ? -91.60864  -27.53966 -80.97850  1.000 54.10466  ? 185 GLU   B OE2 1 
ATOM   4245 N N   . LYS   B 1 186 ? -89.36672  -25.90363 -86.18032  1.000 26.99469  ? 186 LYS   B N   1 
ATOM   4246 C CA  . LYS   B 1 186 ? -90.04102  -24.82818 -86.89926  1.000 29.56790  ? 186 LYS   B CA  1 
ATOM   4247 C C   . LYS   B 1 186 ? -90.18653  -25.16556 -88.37839  1.000 28.29708  ? 186 LYS   B C   1 
ATOM   4248 O O   . LYS   B 1 186 ? -91.22202  -24.86449 -88.98595  1.000 25.93621  ? 186 LYS   B O   1 
ATOM   4249 C CB  . LYS   B 1 186 ? -89.30265  -23.49944 -86.72051  1.000 21.05954  ? 186 LYS   B CB  1 
ATOM   4250 C CG  . LYS   B 1 186 ? -90.22448  -22.29826 -86.85869  1.000 18.94721  ? 186 LYS   B CG  1 
ATOM   4251 C CD  . LYS   B 1 186 ? -89.50860  -20.96341 -86.74758  1.000 17.37173  ? 186 LYS   B CD  1 
ATOM   4252 C CE  . LYS   B 1 186 ? -90.52351  -19.82031 -86.74918  1.000 17.97948  ? 186 LYS   B CE  1 
ATOM   4253 N NZ  . LYS   B 1 186 ? -89.88235  -18.48287 -86.81020  1.000 18.10575  ? 186 LYS   B NZ  1 
ATOM   4254 N N   . ARG   B 1 187 ? -89.16383  -25.79281 -88.97111  1.000 23.04571  ? 187 ARG   B N   1 
ATOM   4255 C CA  . ARG   B 1 187 ? -89.25470  -26.20871 -90.36720  1.000 27.81654  ? 187 ARG   B CA  1 
ATOM   4256 C C   . ARG   B 1 187 ? -90.49009  -27.06521 -90.60819  1.000 31.13419  ? 187 ARG   B C   1 
ATOM   4257 O O   . ARG   B 1 187 ? -91.16080  -26.93122 -91.63939  1.000 30.25085  ? 187 ARG   B O   1 
ATOM   4258 C CB  . ARG   B 1 187 ? -87.99302  -26.97365 -90.76881  1.000 28.46342  ? 187 ARG   B CB  1 
ATOM   4259 C CG  . ARG   B 1 187 ? -88.11321  -27.75279 -92.08156  1.000 29.89970  ? 187 ARG   B CG  1 
ATOM   4260 C CD  . ARG   B 1 187 ? -87.07293  -28.89909 -92.17267  1.000 32.88815  ? 187 ARG   B CD  1 
ATOM   4261 N NE  . ARG   B 1 187 ? -87.48374  -30.06613 -91.39972  1.000 40.86758  ? 187 ARG   B NE  1 
ATOM   4262 C CZ  . ARG   B 1 187 ? -86.65925  -30.88616 -90.75112  1.000 38.31369  ? 187 ARG   B CZ  1 
ATOM   4263 N NH1 . ARG   B 1 187 ? -85.34715  -30.68834 -90.77252  1.000 24.41582  ? 187 ARG   B NH1 1 
ATOM   4264 N NH2 . ARG   B 1 187 ? -87.16145  -31.91301 -90.07455  1.000 33.33288  ? 187 ARG   B NH2 1 
ATOM   4265 N N   . GLU   B 1 188 ? -90.81627  -27.94138 -89.65507  1.000 27.55718  ? 188 GLU   B N   1 
ATOM   4266 C CA  . GLU   B 1 188 ? -91.95176  -28.83440 -89.84214  1.000 30.00367  ? 188 GLU   B CA  1 
ATOM   4267 C C   . GLU   B 1 188 ? -93.26961  -28.07919 -89.73468  1.000 22.97881  ? 188 GLU   B C   1 
ATOM   4268 O O   . GLU   B 1 188 ? -94.21847  -28.36949 -90.47328  1.000 22.95690  ? 188 GLU   B O   1 
ATOM   4269 C CB  . GLU   B 1 188 ? -91.89141  -29.97693 -88.82818  1.000 21.83061  ? 188 GLU   B CB  1 
ATOM   4270 C CG  . GLU   B 1 188 ? -90.85329  -31.02979 -89.16366  1.000 30.46774  ? 188 GLU   B CG  1 
ATOM   4271 C CD  . GLU   B 1 188 ? -91.03133  -31.63323 -90.55205  1.000 34.57619  ? 188 GLU   B CD  1 
ATOM   4272 O OE1 . GLU   B 1 188 ? -92.15862  -32.05868 -90.88179  1.000 32.53501  ? 188 GLU   B OE1 1 
ATOM   4273 O OE2 . GLU   B 1 188 ? -90.03854  -31.68221 -91.31508  1.000 36.13485  ? 188 GLU   B OE2 1 
ATOM   4274 N N   . LYS   B 1 189 ? -93.34862  -27.11782 -88.81089  1.000 21.46170  ? 189 LYS   B N   1 
ATOM   4275 C CA  . LYS   B 1 189 ? -94.53915  -26.28073 -88.71493  1.000 28.15160  ? 189 LYS   B CA  1 
ATOM   4276 C C   . LYS   B 1 189 ? -94.74365  -25.46868 -89.98869  1.000 29.42613  ? 189 LYS   B C   1 
ATOM   4277 O O   . LYS   B 1 189 ? -95.86746  -25.35446 -90.48989  1.000 25.11082  ? 189 LYS   B O   1 
ATOM   4278 C CB  . LYS   B 1 189 ? -94.43703  -25.34417 -87.51360  1.000 28.42767  ? 189 LYS   B CB  1 
ATOM   4279 C CG  . LYS   B 1 189 ? -94.42564  -26.01686 -86.16126  1.000 30.30968  ? 189 LYS   B CG  1 
ATOM   4280 C CD  . LYS   B 1 189 ? -94.44841  -24.97610 -85.05595  1.000 31.56588  ? 189 LYS   B CD  1 
ATOM   4281 C CE  . LYS   B 1 189 ? -94.47061  -25.60871 -83.67765  1.000 33.81412  ? 189 LYS   B CE  1 
ATOM   4282 N NZ  . LYS   B 1 189 ? -94.12373  -24.58548 -82.65962  1.000 38.73694  ? 189 LYS   B NZ  1 
ATOM   4283 N N   . ILE   B 1 190 ? -93.66909  -24.88851 -90.52326  1.000 22.43327  ? 190 ILE   B N   1 
ATOM   4284 C CA  . ILE   B 1 190 ? -93.79654  -24.11787 -91.75290  1.000 26.52779  ? 190 ILE   B CA  1 
ATOM   4285 C C   . ILE   B 1 190 ? -94.22204  -25.02419 -92.89887  1.000 31.21807  ? 190 ILE   B C   1 
ATOM   4286 O O   . ILE   B 1 190 ? -95.08417  -24.66299 -93.71062  1.000 22.84035  ? 190 ILE   B O   1 
ATOM   4287 C CB  . ILE   B 1 190 ? -92.48135  -23.38985 -92.06148  1.000 20.80388  ? 190 ILE   B CB  1 
ATOM   4288 C CG1 . ILE   B 1 190 ? -92.22818  -22.30144 -91.02234  1.000 19.09831  ? 190 ILE   B CG1 1 
ATOM   4289 C CG2 . ILE   B 1 190 ? -92.51045  -22.82788 -93.46584  1.000 16.93542  ? 190 ILE   B CG2 1 
ATOM   4290 C CD1 . ILE   B 1 190 ? -90.81081  -21.73111 -91.08384  1.000 16.03795  ? 190 ILE   B CD1 1 
ATOM   4291 N N   . PHE   B 1 191 ? -93.64082  -26.22513 -92.96545  1.000 28.21442  ? 191 PHE   B N   1 
ATOM   4292 C CA  . PHE   B 1 191 ? -94.06420  -27.21012 -93.95437  1.000 28.75398  ? 191 PHE   B CA  1 
ATOM   4293 C C   . PHE   B 1 191 ? -95.53805  -27.56045 -93.78125  1.000 30.82016  ? 191 PHE   B C   1 
ATOM   4294 O O   . PHE   B 1 191 ? -96.31134  -27.53997 -94.74533  1.000 24.20408  ? 191 PHE   B O   1 
ATOM   4295 C CB  . PHE   B 1 191 ? -93.18957  -28.45844 -93.83798  1.000 26.11791  ? 191 PHE   B CB  1 
ATOM   4296 C CG  . PHE   B 1 191 ? -93.62692  -29.59628 -94.71921  1.000 30.26795  ? 191 PHE   B CG  1 
ATOM   4297 C CD1 . PHE   B 1 191 ? -93.16730  -29.69760 -96.02637  1.000 27.07876  ? 191 PHE   B CD1 1 
ATOM   4298 C CD2 . PHE   B 1 191 ? -94.47336  -30.58275 -94.23197  1.000 28.07836  ? 191 PHE   B CD2 1 
ATOM   4299 C CE1 . PHE   B 1 191 ? -93.55522  -30.75103 -96.82798  1.000 25.09984  ? 191 PHE   B CE1 1 
ATOM   4300 C CE2 . PHE   B 1 191 ? -94.86052  -31.62972 -95.02818  1.000 28.32068  ? 191 PHE   B CE2 1 
ATOM   4301 C CZ  . PHE   B 1 191 ? -94.40044  -31.71495 -96.32756  1.000 28.08776  ? 191 PHE   B CZ  1 
ATOM   4302 N N   . ALA   B 1 192 ? -95.94738  -27.87175 -92.54926  1.000 23.12623  ? 192 ALA   B N   1 
ATOM   4303 C CA  . ALA   B 1 192 ? -97.33581  -28.24672 -92.31124  1.000 28.14308  ? 192 ALA   B CA  1 
ATOM   4304 C C   . ALA   B 1 192 ? -98.28832  -27.12274 -92.71215  1.000 34.15678  ? 192 ALA   B C   1 
ATOM   4305 O O   . ALA   B 1 192 ? -99.32967  -27.37395 -93.32979  1.000 35.97635  ? 192 ALA   B O   1 
ATOM   4306 C CB  . ALA   B 1 192 ? -97.52969  -28.63304 -90.83982  1.000 21.42597  ? 192 ALA   B CB  1 
ATOM   4307 N N   . LEU   B 1 193 ? -97.93713  -25.87529 -92.38663  1.000 28.44723  ? 193 LEU   B N   1 
ATOM   4308 C CA  . LEU   B 1 193 ? -98.79716  -24.74167 -92.71934  1.000 28.69562  ? 193 LEU   B CA  1 
ATOM   4309 C C   . LEU   B 1 193 ? -98.94639  -24.58721 -94.23004  1.000 26.44970  ? 193 LEU   B C   1 
ATOM   4310 O O   . LEU   B 1 193 ? -100.06646 -24.50669 -94.74637  1.000 34.63998  ? 193 LEU   B O   1 
ATOM   4311 C CB  . LEU   B 1 193 ? -98.24365  -23.45767 -92.08761  1.000 24.50124  ? 193 LEU   B CB  1 
ATOM   4312 C CG  . LEU   B 1 193 ? -98.80614  -22.10482 -92.53372  1.000 24.24771  ? 193 LEU   B CG  1 
ATOM   4313 C CD1 . LEU   B 1 193 ? -100.31080 -22.09255 -92.41945  1.000 34.92407  ? 193 LEU   B CD1 1 
ATOM   4314 C CD2 . LEU   B 1 193 ? -98.22513  -20.98446 -91.70011  1.000 27.12071  ? 193 LEU   B CD2 1 
ATOM   4315 N N   . VAL   B 1 194 ? -97.82729  -24.56976 -94.95676  1.000 22.10143  ? 194 VAL   B N   1 
ATOM   4316 C CA  . VAL   B 1 194 ? -97.86965  -24.31871 -96.39529  1.000 24.19547  ? 194 VAL   B CA  1 
ATOM   4317 C C   . VAL   B 1 194 ? -98.56581  -25.46115 -97.12673  1.000 31.14452  ? 194 VAL   B C   1 
ATOM   4318 O O   . VAL   B 1 194 ? -99.30491  -25.23724 -98.09907  1.000 29.74242  ? 194 VAL   B O   1 
ATOM   4319 C CB  . VAL   B 1 194 ? -96.44336  -24.08344 -96.93110  1.000 24.64276  ? 194 VAL   B CB  1 
ATOM   4320 C CG1 . VAL   B 1 194 ? -96.43994  -23.93837 -98.45449  1.000 11.86910  ? 194 VAL   B CG1 1 
ATOM   4321 C CG2 . VAL   B 1 194 ? -95.84484  -22.86316 -96.27562  1.000 18.63084  ? 194 VAL   B CG2 1 
ATOM   4322 N N   . LYS   B 1 195 ? -98.33411  -26.70112 -96.68424  1.000 33.89111  ? 195 LYS   B N   1 
ATOM   4323 C CA  . LYS   B 1 195 ? -99.01466  -27.84115 -97.28701  1.000 29.73415  ? 195 LYS   B CA  1 
ATOM   4324 C C   . LYS   B 1 195 ? -100.51870 -27.67468 -97.17374  1.000 32.21256  ? 195 LYS   B C   1 
ATOM   4325 O O   . LYS   B 1 195 ? -101.25715 -27.82851 -98.15677  1.000 33.60261  ? 195 LYS   B O   1 
ATOM   4326 C CB  . LYS   B 1 195 ? -98.56230  -29.13634 -96.60758  1.000 36.38117  ? 195 LYS   B CB  1 
ATOM   4327 C CG  . LYS   B 1 195 ? -99.18178  -30.40080 -97.19454  1.000 44.87449  ? 195 LYS   B CG  1 
ATOM   4328 C CD  . LYS   B 1 195 ? -98.61996  -31.66766 -96.55036  1.000 39.52477  ? 195 LYS   B CD  1 
ATOM   4329 C CE  . LYS   B 1 195 ? -99.50791  -32.87263 -96.85220  1.000 35.22774  ? 195 LYS   B CE  1 
ATOM   4330 N NZ  . LYS   B 1 195 ? -99.45693  -33.23692 -98.29705  1.000 45.26087  ? 195 LYS   B NZ  1 
ATOM   4331 N N   . SER   B 1 196 ? -100.97991 -27.31418 -95.97683  1.000 27.19430  ? 196 SER   B N   1 
ATOM   4332 C CA  . SER   B 1 196 ? -102.40317 -27.13311 -95.73541  1.000 29.38241  ? 196 SER   B CA  1 
ATOM   4333 C C   . SER   B 1 196 ? -102.99886 -26.11412 -96.70119  1.000 32.71381  ? 196 SER   B C   1 
ATOM   4334 O O   . SER   B 1 196 ? -104.04464 -26.36090 -97.31179  1.000 40.10757  ? 196 SER   B O   1 
ATOM   4335 C CB  . SER   B 1 196 ? -102.61742 -26.72203 -94.27348  1.000 20.33985  ? 196 SER   B CB  1 
ATOM   4336 O OG  . SER   B 1 196 ? -103.90221 -26.16571 -94.06711  1.000 51.05807  ? 196 SER   B OG  1 
ATOM   4337 N N   . LEU   B 1 197 ? -102.33084 -24.97187 -96.88147  1.000 26.62402  ? 197 LEU   B N   1 
ATOM   4338 C CA  . LEU   B 1 197 ? -102.86566 -23.97646 -97.80641  1.000 32.37618  ? 197 LEU   B CA  1 
ATOM   4339 C C   . LEU   B 1 197 ? -102.78109 -24.45914 -99.24886  1.000 31.88921  ? 197 LEU   B C   1 
ATOM   4340 O O   . LEU   B 1 197 ? -103.69758 -24.21512 -100.04430 1.000 31.78457  ? 197 LEU   B O   1 
ATOM   4341 C CB  . LEU   B 1 197 ? -102.13991 -22.64377 -97.65494  1.000 23.47890  ? 197 LEU   B CB  1 
ATOM   4342 C CG  . LEU   B 1 197 ? -102.13832 -22.00372 -96.26953  1.000 33.13816  ? 197 LEU   B CG  1 
ATOM   4343 C CD1 . LEU   B 1 197 ? -100.88377 -21.14298 -96.10736  1.000 23.92708  ? 197 LEU   B CD1 1 
ATOM   4344 C CD2 . LEU   B 1 197 ? -103.40561 -21.19470 -96.04502  1.000 20.04532  ? 197 LEU   B CD2 1 
ATOM   4345 N N   . ARG   B 1 198 ? -101.68609 -25.13787 -99.60775  1.000 32.94971  ? 198 ARG   B N   1 
ATOM   4346 C CA  . ARG   B 1 198 ? -101.56726 -25.69607 -100.95185 1.000 34.37235  ? 198 ARG   B CA  1 
ATOM   4347 C C   . ARG   B 1 198 ? -102.67837 -26.70210 -101.22206 1.000 35.43341  ? 198 ARG   B C   1 
ATOM   4348 O O   . ARG   B 1 198 ? -103.33533 -26.65587 -102.26925 1.000 34.49415  ? 198 ARG   B O   1 
ATOM   4349 C CB  . ARG   B 1 198 ? -100.19671 -26.35496 -101.13387 1.000 34.70317  ? 198 ARG   B CB  1 
ATOM   4350 C CG  . ARG   B 1 198 ? -99.04653  -25.38490 -101.22823 1.000 30.73077  ? 198 ARG   B CG  1 
ATOM   4351 C CD  . ARG   B 1 198 ? -98.89567  -24.87432 -102.63383 1.000 27.99041  ? 198 ARG   B CD  1 
ATOM   4352 N NE  . ARG   B 1 198 ? -98.10857  -25.77847 -103.46392 1.000 36.42369  ? 198 ARG   B NE  1 
ATOM   4353 C CZ  . ARG   B 1 198 ? -97.61773  -25.45502 -104.65622 1.000 31.78798  ? 198 ARG   B CZ  1 
ATOM   4354 N NH1 . ARG   B 1 198 ? -97.83222  -24.24102 -105.16159 1.000 28.77319  ? 198 ARG   B NH1 1 
ATOM   4355 N NH2 . ARG   B 1 198 ? -96.92041  -26.34912 -105.34451 1.000 28.21460  ? 198 ARG   B NH2 1 
ATOM   4356 N N   . ASP   B 1 199 ? -102.89994 -27.62242 -100.28043 1.000 32.48297  ? 199 ASP   B N   1 
ATOM   4357 C CA  . ASP   B 1 199 ? -103.92124 -28.64724 -100.46832 1.000 36.43299  ? 199 ASP   B CA  1 
ATOM   4358 C C   . ASP   B 1 199 ? -105.31181 -28.03757 -100.60387 1.000 37.28949  ? 199 ASP   B C   1 
ATOM   4359 O O   . ASP   B 1 199 ? -106.13607 -28.55342 -101.36604 1.000 44.18952  ? 199 ASP   B O   1 
ATOM   4360 C CB  . ASP   B 1 199 ? -103.88399 -29.65166 -99.30827  1.000 31.39354  ? 199 ASP   B CB  1 
ATOM   4361 C CG  . ASP   B 1 199 ? -102.63946 -30.53214 -99.33173  1.000 32.70408  ? 199 ASP   B CG  1 
ATOM   4362 O OD1 . ASP   B 1 199 ? -101.92144 -30.52448 -100.36221 1.000 36.81674  ? 199 ASP   B OD1 1 
ATOM   4363 O OD2 . ASP   B 1 199 ? -102.37379 -31.22108 -98.31620  1.000 35.77937  ? 199 ASP   B OD2 1 
ATOM   4364 N N   . LYS   B 1 200 ? -105.59029 -26.93834 -99.89341  1.000 30.33399  ? 200 LYS   B N   1 
ATOM   4365 C CA  . LYS   B 1 200 ? -106.88837 -26.27612 -100.01662 1.000 27.96414  ? 200 LYS   B CA  1 
ATOM   4366 C C   . LYS   B 1 200 ? -107.03159 -25.49499 -101.30554 1.000 29.98935  ? 200 LYS   B C   1 
ATOM   4367 O O   . LYS   B 1 200 ? -108.06936 -24.85907 -101.49967 1.000 33.31868  ? 200 LYS   B O   1 
ATOM   4368 C CB  . LYS   B 1 200 ? -107.13662 -25.32748 -98.84499  1.000 29.42931  ? 200 LYS   B CB  1 
ATOM   4369 C CG  . LYS   B 1 200 ? -107.26454 -26.02306 -97.50250  1.000 40.44563  ? 200 LYS   B CG  1 
ATOM   4370 C CD  . LYS   B 1 200 ? -107.05235 -25.05277 -96.36384  1.000 37.56147  ? 200 LYS   B CD  1 
ATOM   4371 C CE  . LYS   B 1 200 ? -108.26919 -25.02397 -95.47531  1.000 55.47307  ? 200 LYS   B CE  1 
ATOM   4372 N NZ  . LYS   B 1 200 ? -107.88043 -25.21627 -94.05077  1.000 53.77738  ? 200 LYS   B NZ  1 
ATOM   4373 N N   . GLY   B 1 201 ? -106.03542 -25.51110 -102.18194 1.000 22.81159  ? 201 GLY   B N   1 
ATOM   4374 C CA  . GLY   B 1 201 ? -106.12204 -24.73531 -103.39988 1.000 28.86274  ? 201 GLY   B CA  1 
ATOM   4375 C C   . GLY   B 1 201 ? -105.81443 -23.26026 -103.25525 1.000 37.04789  ? 201 GLY   B C   1 
ATOM   4376 O O   . GLY   B 1 201 ? -106.07503 -22.49363 -104.19516 1.000 31.56905  ? 201 GLY   B O   1 
ATOM   4377 N N   . ILE   B 1 202 ? -105.27258 -22.83825 -102.11694 1.000 32.50808  ? 202 ILE   B N   1 
ATOM   4378 C CA  . ILE   B 1 202 ? -104.93306 -21.42356 -101.92074 1.000 27.21745  ? 202 ILE   B CA  1 
ATOM   4379 C C   . ILE   B 1 202 ? -103.79962 -21.04433 -102.86711 1.000 25.19936  ? 202 ILE   B C   1 
ATOM   4380 O O   . ILE   B 1 202 ? -102.84346 -21.82541 -103.02704 1.000 24.24602  ? 202 ILE   B O   1 
ATOM   4381 C CB  . ILE   B 1 202 ? -104.54893 -21.17048 -100.46053 1.000 27.13692  ? 202 ILE   B CB  1 
ATOM   4382 C CG1 . ILE   B 1 202 ? -105.75511 -21.41714 -99.54229  1.000 22.29594  ? 202 ILE   B CG1 1 
ATOM   4383 C CG2 . ILE   B 1 202 ? -103.98906 -19.77006 -100.27397 1.000 23.27046  ? 202 ILE   B CG2 1 
ATOM   4384 C CD1 . ILE   B 1 202 ? -106.98830 -20.66613 -99.94274  1.000 19.70939  ? 202 ILE   B CD1 1 
ATOM   4385 N N   . PRO   B 1 203 ? -103.86165 -19.87786 -103.52054 1.000 25.51953  ? 203 PRO   B N   1 
ATOM   4386 C CA  . PRO   B 1 203 ? -102.77429 -19.46819 -104.41666 1.000 23.64833  ? 203 PRO   B CA  1 
ATOM   4387 C C   . PRO   B 1 203 ? -101.50979 -19.02673 -103.67937 1.000 28.96704  ? 203 PRO   B C   1 
ATOM   4388 O O   . PRO   B 1 203 ? -101.14329 -17.84746 -103.68911 1.000 31.21803  ? 203 PRO   B O   1 
ATOM   4389 C CB  . PRO   B 1 203 ? -103.39895 -18.30608 -105.20123 1.000 20.97052  ? 203 PRO   B CB  1 
ATOM   4390 C CG  . PRO   B 1 203 ? -104.38503 -17.71354 -104.23571 1.000 25.25957  ? 203 PRO   B CG  1 
ATOM   4391 C CD  . PRO   B 1 203 ? -104.97266 -18.90395 -103.51710 1.000 27.40241  ? 203 PRO   B CD  1 
ATOM   4392 N N   . ILE   B 1 204 ? -100.82010 -19.96739 -103.04795 1.000 28.77061  ? 204 ILE   B N   1 
ATOM   4393 C CA  . ILE   B 1 204 ? -99.52322  -19.71401 -102.43736 1.000 25.72100  ? 204 ILE   B CA  1 
ATOM   4394 C C   . ILE   B 1 204 ? -98.48382  -20.39961 -103.31156 1.000 32.66840  ? 204 ILE   B C   1 
ATOM   4395 O O   . ILE   B 1 204 ? -98.56481  -21.60764 -103.56319 1.000 34.12140  ? 204 ILE   B O   1 
ATOM   4396 C CB  . ILE   B 1 204 ? -99.47431  -20.19395 -100.97510 1.000 28.48129  ? 204 ILE   B CB  1 
ATOM   4397 C CG1 . ILE   B 1 204 ? -98.04879  -20.14866 -100.42644 1.000 25.98343  ? 204 ILE   B CG1 1 
ATOM   4398 C CG2 . ILE   B 1 204 ? -100.09286 -21.58311 -100.81826 1.000 30.69657  ? 204 ILE   B CG2 1 
ATOM   4399 C CD1 . ILE   B 1 204 ? -97.98868  -20.25514 -98.91021  1.000 20.81371  ? 204 ILE   B CD1 1 
ATOM   4400 N N   . HIS   B 1 205 ? -97.53182  -19.62408 -103.81759 1.000 26.01878  ? 205 HIS   B N   1 
ATOM   4401 C CA  . HIS   B 1 205 ? -96.59718  -20.14155 -104.80153 1.000 23.77542  ? 205 HIS   B CA  1 
ATOM   4402 C C   . HIS   B 1 205 ? -95.17427  -20.33323 -104.28576 1.000 25.21101  ? 205 HIS   B C   1 
ATOM   4403 O O   . HIS   B 1 205 ? -94.41426  -21.09096 -104.89623 1.000 28.51449  ? 205 HIS   B O   1 
ATOM   4404 C CB  . HIS   B 1 205 ? -96.56806  -19.21096 -106.02034 1.000 23.68727  ? 205 HIS   B CB  1 
ATOM   4405 C CG  . HIS   B 1 205 ? -97.92253  -18.74835 -106.44964 1.000 31.51077  ? 205 HIS   B CG  1 
ATOM   4406 N ND1 . HIS   B 1 205 ? -98.41509  -17.50119 -106.13722 1.000 23.84312  ? 205 HIS   B ND1 1 
ATOM   4407 C CD2 . HIS   B 1 205 ? -98.89423  -19.37070 -107.16251 1.000 27.34201  ? 205 HIS   B CD2 1 
ATOM   4408 C CE1 . HIS   B 1 205 ? -99.62774  -17.36969 -106.64503 1.000 31.13158  ? 205 HIS   B CE1 1 
ATOM   4409 N NE2 . HIS   B 1 205 ? -99.94259  -18.49061 -107.27100 1.000 28.28135  ? 205 HIS   B NE2 1 
ATOM   4410 N N   . GLY   B 1 206 ? -94.79198  -19.68307 -103.19133 1.000 23.36286  ? 206 GLY   B N   1 
ATOM   4411 C CA  . GLY   B 1 206 ? -93.40463  -19.70595 -102.77390 1.000 18.66116  ? 206 GLY   B CA  1 
ATOM   4412 C C   . GLY   B 1 206 ? -93.24320  -19.67492 -101.27029 1.000 25.49038  ? 206 GLY   B C   1 
ATOM   4413 O O   . GLY   B 1 206 ? -94.12681  -19.23191 -100.52583 1.000 22.83782  ? 206 GLY   B O   1 
ATOM   4414 N N   . ILE   B 1 207 ? -92.09262  -20.17217 -100.82889 1.000 23.06921  ? 207 ILE   B N   1 
ATOM   4415 C CA  . ILE   B 1 207 ? -91.67185  -20.06784 -99.44160  1.000 20.17926  ? 207 ILE   B CA  1 
ATOM   4416 C C   . ILE   B 1 207 ? -90.44507  -19.18040 -99.42574  1.000 20.35441  ? 207 ILE   B C   1 
ATOM   4417 O O   . ILE   B 1 207 ? -89.53145  -19.37103 -100.23842 1.000 15.53496  ? 207 ILE   B O   1 
ATOM   4418 C CB  . ILE   B 1 207 ? -91.37473  -21.44188 -98.81862  1.000 22.20957  ? 207 ILE   B CB  1 
ATOM   4419 C CG1 . ILE   B 1 207 ? -92.67835  -22.14109 -98.44468  1.000 17.20954  ? 207 ILE   B CG1 1 
ATOM   4420 C CG2 . ILE   B 1 207 ? -90.46440  -21.29789 -97.60237  1.000 12.80748  ? 207 ILE   B CG2 1 
ATOM   4421 C CD1 . ILE   B 1 207 ? -92.47915  -23.52009 -97.89734  1.000 23.82672  ? 207 ILE   B CD1 1 
ATOM   4422 N N   . GLY   B 1 208 ? -90.45620  -18.17847 -98.55076  1.000 17.18810  ? 208 GLY   B N   1 
ATOM   4423 C CA  . GLY   B 1 208 ? -89.32508  -17.30464 -98.36351  1.000 17.55313  ? 208 GLY   B CA  1 
ATOM   4424 C C   . GLY   B 1 208 ? -88.56513  -17.74027 -97.13043  1.000 20.13173  ? 208 GLY   B C   1 
ATOM   4425 O O   . GLY   B 1 208 ? -89.10878  -17.74691 -96.01839  1.000 19.73184  ? 208 GLY   B O   1 
ATOM   4426 N N   . MET   B 1 209 ? -87.31371  -18.14181 -97.33345  1.000 17.58493  ? 209 MET   B N   1 
ATOM   4427 C CA  . MET   B 1 209 ? -86.40360  -18.46514 -96.23902  1.000 20.24136  ? 209 MET   B CA  1 
ATOM   4428 C C   . MET   B 1 209 ? -85.59163  -17.21459 -95.92236  1.000 20.05196  ? 209 MET   B C   1 
ATOM   4429 O O   . MET   B 1 209 ? -84.73706  -16.79753 -96.71842  1.000 14.88053  ? 209 MET   B O   1 
ATOM   4430 C CB  . MET   B 1 209 ? -85.50915  -19.63920 -96.61582  1.000 16.63327  ? 209 MET   B CB  1 
ATOM   4431 C CG  . MET   B 1 209 ? -86.30754  -20.91298 -96.93645  1.000 24.18284  ? 209 MET   B CG  1 
ATOM   4432 S SD  . MET   B 1 209 ? -85.32088  -22.22188 -97.71818  1.000 24.31592  ? 209 MET   B SD  1 
ATOM   4433 C CE  . MET   B 1 209 ? -84.02641  -22.43908 -96.51262  1.000 15.26013  ? 209 MET   B CE  1 
ATOM   4434 N N   . GLN   B 1 210 ? -85.87722  -16.60410 -94.76818  1.000 14.02801  ? 210 GLN   B N   1 
ATOM   4435 C CA  . GLN   B 1 210 ? -85.21438  -15.35119 -94.43037  1.000 18.74164  ? 210 GLN   B CA  1 
ATOM   4436 C C   . GLN   B 1 210 ? -83.70943  -15.54073 -94.30762  1.000 17.87152  ? 210 GLN   B C   1 
ATOM   4437 O O   . GLN   B 1 210 ? -82.94168  -14.67753 -94.73777  1.000 18.88662  ? 210 GLN   B O   1 
ATOM   4438 C CB  . GLN   B 1 210 ? -85.79643  -14.77340 -93.14033  1.000 20.10367  ? 210 GLN   B CB  1 
ATOM   4439 C CG  . GLN   B 1 210 ? -87.17581  -14.13636 -93.30387  1.000 12.80979  ? 210 GLN   B CG  1 
ATOM   4440 C CD  . GLN   B 1 210 ? -87.64402  -13.49428 -92.02199  1.000 20.01216  ? 210 GLN   B CD  1 
ATOM   4441 O OE1 . GLN   B 1 210 ? -86.82635  -13.16080 -91.16053  1.000 17.58182  ? 210 GLN   B OE1 1 
ATOM   4442 N NE2 . GLN   B 1 210 ? -88.95763  -13.30936 -91.88156  1.000 15.08522  ? 210 GLN   B NE2 1 
ATOM   4443 N N   . ALA   B 1 211 ? -83.27163  -16.66919 -93.72912  1.000 13.45958  ? 211 ALA   B N   1 
ATOM   4444 C CA  . ALA   B 1 211 ? -81.85148  -17.01606 -93.60117  1.000 15.09140  ? 211 ALA   B CA  1 
ATOM   4445 C C   . ALA   B 1 211 ? -81.06677  -15.98080 -92.79513  1.000 17.97714  ? 211 ALA   B C   1 
ATOM   4446 O O   . ALA   B 1 211 ? -80.00082  -15.51698 -93.21273  1.000 17.69175  ? 211 ALA   B O   1 
ATOM   4447 C CB  . ALA   B 1 211 ? -81.20227  -17.22411 -94.96951  1.000 15.11892  ? 211 ALA   B CB  1 
ATOM   4448 N N   . HIS   B 1 212 ? -81.60174  -15.61427 -91.62816  1.000 16.17876  ? 212 HIS   B N   1 
ATOM   4449 C CA  . HIS   B 1 212 ? -80.84836  -14.81782 -90.65631  1.000 17.37893  ? 212 HIS   B CA  1 
ATOM   4450 C C   . HIS   B 1 212 ? -80.01459  -15.77891 -89.82511  1.000 18.66908  ? 212 HIS   B C   1 
ATOM   4451 O O   . HIS   B 1 212 ? -80.49554  -16.35871 -88.85337  1.000 22.19261  ? 212 HIS   B O   1 
ATOM   4452 C CB  . HIS   B 1 212 ? -81.78144  -13.98567 -89.79323  1.000 9.23162   ? 212 HIS   B CB  1 
ATOM   4453 C CG  . HIS   B 1 212 ? -82.44024  -12.87111 -90.54505  1.000 18.16295  ? 212 HIS   B CG  1 
ATOM   4454 N ND1 . HIS   B 1 212 ? -81.72341  -11.87384 -91.17443  1.000 15.17409  ? 212 HIS   B ND1 1 
ATOM   4455 C CD2 . HIS   B 1 212 ? -83.74522  -12.60245 -90.78139  1.000 11.06887  ? 212 HIS   B CD2 1 
ATOM   4456 C CE1 . HIS   B 1 212 ? -82.55912  -11.03657 -91.75950  1.000 13.44360  ? 212 HIS   B CE1 1 
ATOM   4457 N NE2 . HIS   B 1 212 ? -83.79025  -11.45878 -91.54219  1.000 11.64901  ? 212 HIS   B NE2 1 
ATOM   4458 N N   . TRP   B 1 213 ? -78.75941  -15.95916 -90.21405  1.000 17.55527  ? 213 TRP   B N   1 
ATOM   4459 C CA  . TRP   B 1 213 ? -77.96505  -17.07617 -89.74198  1.000 16.55937  ? 213 TRP   B CA  1 
ATOM   4460 C C   . TRP   B 1 213 ? -76.73028  -16.59980 -88.98218  1.000 17.22734  ? 213 TRP   B C   1 
ATOM   4461 O O   . TRP   B 1 213 ? -76.33140  -15.43092 -89.05728  1.000 18.25984  ? 213 TRP   B O   1 
ATOM   4462 C CB  . TRP   B 1 213 ? -77.55869  -17.95080 -90.92343  1.000 16.69727  ? 213 TRP   B CB  1 
ATOM   4463 C CG  . TRP   B 1 213 ? -78.70922  -18.65781 -91.57507  1.000 15.22737  ? 213 TRP   B CG  1 
ATOM   4464 C CD1 . TRP   B 1 213 ? -79.96078  -18.86688 -91.05233  1.000 16.20608  ? 213 TRP   B CD1 1 
ATOM   4465 C CD2 . TRP   B 1 213 ? -78.71091  -19.26284 -92.87614  1.000 15.82008  ? 213 TRP   B CD2 1 
ATOM   4466 N NE1 . TRP   B 1 213 ? -80.73133  -19.58401 -91.94648  1.000 19.17810  ? 213 TRP   B NE1 1 
ATOM   4467 C CE2 . TRP   B 1 213 ? -79.98885  -19.83024 -93.07448  1.000 15.97671  ? 213 TRP   B CE2 1 
ATOM   4468 C CE3 . TRP   B 1 213 ? -77.75548  -19.37304 -93.89823  1.000 16.44494  ? 213 TRP   B CE3 1 
ATOM   4469 C CZ2 . TRP   B 1 213 ? -80.32938  -20.50366 -94.24806  1.000 16.62515  ? 213 TRP   B CZ2 1 
ATOM   4470 C CZ3 . TRP   B 1 213 ? -78.09767  -20.03445 -95.06527  1.000 16.58058  ? 213 TRP   B CZ3 1 
ATOM   4471 C CH2 . TRP   B 1 213 ? -79.37453  -20.59036 -95.23267  1.000 12.66348  ? 213 TRP   B CH2 1 
ATOM   4472 N N   . SER   B 1 214 ? -76.12891  -17.52580 -88.23915  1.000 15.72618  ? 214 SER   B N   1 
ATOM   4473 C CA  . SER   B 1 214 ? -74.87325  -17.30127 -87.52858  1.000 19.36767  ? 214 SER   B CA  1 
ATOM   4474 C C   . SER   B 1 214 ? -73.73793  -18.03760 -88.24279  1.000 18.71021  ? 214 SER   B C   1 
ATOM   4475 O O   . SER   B 1 214 ? -73.91787  -18.65311 -89.29735  1.000 16.03247  ? 214 SER   B O   1 
ATOM   4476 C CB  . SER   B 1 214 ? -74.97624  -17.76215 -86.07503  1.000 19.41719  ? 214 SER   B CB  1 
ATOM   4477 O OG  . SER   B 1 214 ? -74.97328  -19.18496 -86.00607  1.000 20.37524  ? 214 SER   B OG  1 
ATOM   4478 N N   . LEU   B 1 215 ? -72.54845  -17.97676 -87.64728  1.000 22.70403  ? 215 LEU   B N   1 
ATOM   4479 C CA  . LEU   B 1 215 ? -71.40388  -18.67110 -88.22618  1.000 18.16248  ? 215 LEU   B CA  1 
ATOM   4480 C C   . LEU   B 1 215 ? -71.55991  -20.18373 -88.15635  1.000 23.79135  ? 215 LEU   B C   1 
ATOM   4481 O O   . LEU   B 1 215 ? -70.93487  -20.88810 -88.95468  1.000 23.03281  ? 215 LEU   B O   1 
ATOM   4482 C CB  . LEU   B 1 215 ? -70.12443  -18.23306 -87.52607  1.000 14.68993  ? 215 LEU   B CB  1 
ATOM   4483 C CG  . LEU   B 1 215 ? -69.73699  -16.77328 -87.77637  1.000 18.60429  ? 215 LEU   B CG  1 
ATOM   4484 C CD1 . LEU   B 1 215 ? -68.65914  -16.27511 -86.82041  1.000 13.67790  ? 215 LEU   B CD1 1 
ATOM   4485 C CD2 . LEU   B 1 215 ? -69.28909  -16.60098 -89.20458  1.000 9.54368   ? 215 LEU   B CD2 1 
ATOM   4486 N N   . THR   B 1 216 ? -72.40124  -20.69041 -87.24269  1.000 17.09648  ? 216 THR   B N   1 
ATOM   4487 C CA  . THR   B 1 216 ? -72.59755  -22.12384 -87.06537  1.000 19.81294  ? 216 THR   B CA  1 
ATOM   4488 C C   . THR   B 1 216 ? -74.04659  -22.58723 -87.14937  1.000 21.54933  ? 216 THR   B C   1 
ATOM   4489 O O   . THR   B 1 216 ? -74.27124  -23.77602 -87.39964  1.000 23.82784  ? 216 THR   B O   1 
ATOM   4490 C CB  . THR   B 1 216 ? -72.04347  -22.58585 -85.70633  1.000 20.38514  ? 216 THR   B CB  1 
ATOM   4491 O OG1 . THR   B 1 216 ? -72.83811  -22.01770 -84.66475  1.000 24.29153  ? 216 THR   B OG1 1 
ATOM   4492 C CG2 . THR   B 1 216 ? -70.59198  -22.16389 -85.52263  1.000 15.11466  ? 216 THR   B CG2 1 
ATOM   4493 N N   . ARG   B 1 217 ? -75.03263  -21.72460 -86.92678  1.000 24.02817  ? 217 ARG   B N   1 
ATOM   4494 C CA  . ARG   B 1 217 ? -76.40991  -22.19504 -86.89953  1.000 23.88893  ? 217 ARG   B CA  1 
ATOM   4495 C C   . ARG   B 1 217 ? -77.23572  -21.46586 -87.94799  1.000 22.27510  ? 217 ARG   B C   1 
ATOM   4496 O O   . ARG   B 1 217 ? -77.12900  -20.23610 -88.06931  1.000 24.45810  ? 217 ARG   B O   1 
ATOM   4497 C CB  . ARG   B 1 217 ? -77.02686  -22.00327 -85.50602  1.000 30.82377  ? 217 ARG   B CB  1 
ATOM   4498 C CG  . ARG   B 1 217 ? -76.43973  -22.95138 -84.45304  1.000 32.83375  ? 217 ARG   B CG  1 
ATOM   4499 C CD  . ARG   B 1 217 ? -76.81761  -22.56817 -83.00936  1.000 45.30852  ? 217 ARG   B CD  1 
ATOM   4500 N NE  . ARG   B 1 217 ? -78.26019  -22.42538 -82.78602  1.000 54.79182  ? 217 ARG   B NE  1 
ATOM   4501 C CZ  . ARG   B 1 217 ? -79.13145  -23.43624 -82.75219  1.000 58.79187  ? 217 ARG   B CZ  1 
ATOM   4502 N NH1 . ARG   B 1 217 ? -78.72346  -24.68753 -82.93878  1.000 46.67127  ? 217 ARG   B NH1 1 
ATOM   4503 N NH2 . ARG   B 1 217 ? -80.42250  -23.19629 -82.53063  1.000 49.51096  ? 217 ARG   B NH2 1 
ATOM   4504 N N   . PRO   B 1 218 ? -78.04629  -22.17814 -88.74002  1.000 23.80027  ? 218 PRO   B N   1 
ATOM   4505 C CA  . PRO   B 1 218 ? -78.17041  -23.63758 -88.70069  1.000 18.73037  ? 218 PRO   B CA  1 
ATOM   4506 C C   . PRO   B 1 218 ? -76.97361  -24.33003 -89.33575  1.000 24.40253  ? 218 PRO   B C   1 
ATOM   4507 O O   . PRO   B 1 218 ? -76.13154  -23.68041 -89.96827  1.000 24.21161  ? 218 PRO   B O   1 
ATOM   4508 C CB  . PRO   B 1 218 ? -79.43287  -23.90074 -89.51767  1.000 21.75361  ? 218 PRO   B CB  1 
ATOM   4509 C CG  . PRO   B 1 218 ? -79.48224  -22.74461 -90.50816  1.000 17.08055  ? 218 PRO   B CG  1 
ATOM   4510 C CD  . PRO   B 1 218 ? -78.93528  -21.57139 -89.74937  1.000 20.87575  ? 218 PRO   B CD  1 
ATOM   4511 N N   . SER   B 1 219 ? -76.89339  -25.64076 -89.14526  1.000 23.87608  ? 219 SER   B N   1 
ATOM   4512 C CA  . SER   B 1 219 ? -75.85407  -26.42997 -89.77866  1.000 23.16919  ? 219 SER   B CA  1 
ATOM   4513 C C   . SER   B 1 219 ? -76.18320  -26.64685 -91.25291  1.000 24.66411  ? 219 SER   B C   1 
ATOM   4514 O O   . SER   B 1 219 ? -77.34432  -26.57253 -91.68209  1.000 20.65463  ? 219 SER   B O   1 
ATOM   4515 C CB  . SER   B 1 219 ? -75.69906  -27.77458 -89.07372  1.000 17.96787  ? 219 SER   B CB  1 
ATOM   4516 O OG  . SER   B 1 219 ? -76.76859  -28.63910 -89.41809  1.000 25.85859  ? 219 SER   B OG  1 
ATOM   4517 N N   . LEU   B 1 220 ? -75.13330  -26.90452 -92.03569  1.000 24.00500  ? 220 LEU   B N   1 
ATOM   4518 C CA  . LEU   B 1 220 ? -75.32316  -27.19683 -93.45465  1.000 25.99164  ? 220 LEU   B CA  1 
ATOM   4519 C C   . LEU   B 1 220 ? -76.37088  -28.27430 -93.67076  1.000 23.11217  ? 220 LEU   B C   1 
ATOM   4520 O O   . LEU   B 1 220 ? -77.18400  -28.18243 -94.59543  1.000 31.12922  ? 220 LEU   B O   1 
ATOM   4521 C CB  . LEU   B 1 220 ? -73.99991  -27.62727 -94.08184  1.000 24.62125  ? 220 LEU   B CB  1 
ATOM   4522 C CG  . LEU   B 1 220 ? -73.04366  -26.46293 -94.27793  1.000 25.62071  ? 220 LEU   B CG  1 
ATOM   4523 C CD1 . LEU   B 1 220 ? -71.73782  -26.94989 -94.88316  1.000 24.71627  ? 220 LEU   B CD1 1 
ATOM   4524 C CD2 . LEU   B 1 220 ? -73.71680  -25.40279 -95.16225  1.000 23.18359  ? 220 LEU   B CD2 1 
ATOM   4525 N N   . ASP   B 1 221 ? -76.36870  -29.30458 -92.82560  1.000 20.24701  ? 221 ASP   B N   1 
ATOM   4526 C CA  . ASP   B 1 221 ? -77.31827  -30.39613 -93.00475  1.000 29.37764  ? 221 ASP   B CA  1 
ATOM   4527 C C   . ASP   B 1 221 ? -78.74271  -29.93132 -92.74940  1.000 28.10972  ? 221 ASP   B C   1 
ATOM   4528 O O   . ASP   B 1 221 ? -79.67288  -30.36463 -93.43585  1.000 26.67028  ? 221 ASP   B O   1 
ATOM   4529 C CB  . ASP   B 1 221 ? -76.96655  -31.56718 -92.08152  1.000 34.34901  ? 221 ASP   B CB  1 
ATOM   4530 C CG  . ASP   B 1 221 ? -75.68869  -32.28798 -92.49628  1.000 38.05145  ? 221 ASP   B CG  1 
ATOM   4531 O OD1 . ASP   B 1 221 ? -75.25541  -32.16993 -93.67147  1.000 35.81130  ? 221 ASP   B OD1 1 
ATOM   4532 O OD2 . ASP   B 1 221 ? -75.12164  -32.98710 -91.63310  1.000 40.93784  ? 221 ASP   B OD2 1 
ATOM   4533 N N   . GLU   B 1 222 ? -78.93762  -29.05938 -91.75646  1.000 28.66602  ? 222 GLU   B N   1 
ATOM   4534 C CA  . GLU   B 1 222 ? -80.27251  -28.52509 -91.51858  1.000 23.96022  ? 222 GLU   B CA  1 
ATOM   4535 C C   . GLU   B 1 222 ? -80.74035  -27.69561 -92.70638  1.000 26.89313  ? 222 GLU   B C   1 
ATOM   4536 O O   . GLU   B 1 222 ? -81.91697  -27.75234 -93.09065  1.000 21.34972  ? 222 GLU   B O   1 
ATOM   4537 C CB  . GLU   B 1 222 ? -80.28632  -27.70065 -90.23409  1.000 20.62850  ? 222 GLU   B CB  1 
ATOM   4538 C CG  . GLU   B 1 222 ? -79.93400  -28.51335 -89.01383  1.000 22.89743  ? 222 GLU   B CG  1 
ATOM   4539 C CD  . GLU   B 1 222 ? -79.79701  -27.67184 -87.76002  1.000 28.21594  ? 222 GLU   B CD  1 
ATOM   4540 O OE1 . GLU   B 1 222 ? -79.11867  -26.62134 -87.80701  1.000 23.26459  ? 222 GLU   B OE1 1 
ATOM   4541 O OE2 . GLU   B 1 222 ? -80.37131  -28.06484 -86.72261  1.000 26.53707  ? 222 GLU   B OE2 1 
ATOM   4542 N N   . ILE   B 1 223 ? -79.82864  -26.93010 -93.31402  1.000 23.49497  ? 223 ILE   B N   1 
ATOM   4543 C CA  . ILE   B 1 223 ? -80.21174  -26.12963 -94.46879  1.000 22.46804  ? 223 ILE   B CA  1 
ATOM   4544 C C   . ILE   B 1 223 ? -80.58630  -27.03770 -95.62812  1.000 26.78989  ? 223 ILE   B C   1 
ATOM   4545 O O   . ILE   B 1 223 ? -81.61330  -26.84128 -96.28477  1.000 27.91256  ? 223 ILE   B O   1 
ATOM   4546 C CB  . ILE   B 1 223 ? -79.08988  -25.15813 -94.86664  1.000 22.50623  ? 223 ILE   B CB  1 
ATOM   4547 C CG1 . ILE   B 1 223 ? -78.74649  -24.20576 -93.72842  1.000 19.35557  ? 223 ILE   B CG1 1 
ATOM   4548 C CG2 . ILE   B 1 223 ? -79.48865  -24.37051 -96.12332  1.000 17.26218  ? 223 ILE   B CG2 1 
ATOM   4549 C CD1 . ILE   B 1 223 ? -77.43866  -23.44172 -93.98672  1.000 16.40997  ? 223 ILE   B CD1 1 
ATOM   4550 N N   . ARG   B 1 224 ? -79.76191  -28.04834 -95.89721  1.000 25.79409  ? 224 ARG   B N   1 
ATOM   4551 C CA  . ARG   B 1 224 ? -80.09540  -28.98434 -96.96258  1.000 29.40004  ? 224 ARG   B CA  1 
ATOM   4552 C C   . ARG   B 1 224 ? -81.43840  -29.64559 -96.68357  1.000 29.54964  ? 224 ARG   B C   1 
ATOM   4553 O O   . ARG   B 1 224 ? -82.30248  -29.73040 -97.56732  1.000 26.45133  ? 224 ARG   B O   1 
ATOM   4554 C CB  . ARG   B 1 224 ? -78.98716  -30.02649 -97.10834  1.000 29.30817  ? 224 ARG   B CB  1 
ATOM   4555 C CG  . ARG   B 1 224 ? -79.25102  -31.05258 -98.18941  1.000 29.18778  ? 224 ARG   B CG  1 
ATOM   4556 C CD  . ARG   B 1 224 ? -78.12903  -32.07694 -98.27409  1.000 42.11461  ? 224 ARG   B CD  1 
ATOM   4557 N NE  . ARG   B 1 224 ? -76.81413  -31.47466 -98.51116  1.000 36.44392  ? 224 ARG   B NE  1 
ATOM   4558 C CZ  . ARG   B 1 224 ? -76.26645  -31.33957 -99.71606  1.000 32.15703  ? 224 ARG   B CZ  1 
ATOM   4559 N NH1 . ARG   B 1 224 ? -76.92189  -31.75703 -100.79129 1.000 35.88975  ? 224 ARG   B NH1 1 
ATOM   4560 N NH2 . ARG   B 1 224 ? -75.06827  -30.79301 -99.85064  1.000 26.34671  ? 224 ARG   B NH2 1 
ATOM   4561 N N   . ALA   B 1 225 ? -81.63750  -30.08558 -95.43726  1.000 26.13973  ? 225 ALA   B N   1 
ATOM   4562 C CA  . ALA   B 1 225 ? -82.89961  -30.69488 -95.03856  1.000 28.95393  ? 225 ALA   B CA  1 
ATOM   4563 C C   . ALA   B 1 225 ? -84.07312  -29.76747 -95.32259  1.000 32.90726  ? 225 ALA   B C   1 
ATOM   4564 O O   . ALA   B 1 225 ? -85.06570  -30.17376 -95.94169  1.000 32.49704  ? 225 ALA   B O   1 
ATOM   4565 C CB  . ALA   B 1 225 ? -82.85319  -31.05836 -93.55494  1.000 24.47442  ? 225 ALA   B CB  1 
ATOM   4566 N N   . ALA   B 1 226 ? -83.97568  -28.51203 -94.87548  1.000 26.15406  ? 226 ALA   B N   1 
ATOM   4567 C CA  . ALA   B 1 226 ? -85.06889  -27.56747 -95.07998  1.000 24.36989  ? 226 ALA   B CA  1 
ATOM   4568 C C   . ALA   B 1 226 ? -85.34677  -27.35907 -96.56441  1.000 29.70067  ? 226 ALA   B C   1 
ATOM   4569 O O   . ALA   B 1 226 ? -86.50201  -27.42208 -97.00423  1.000 24.82541  ? 226 ALA   B O   1 
ATOM   4570 C CB  . ALA   B 1 226 ? -84.74457  -26.24348 -94.39813  1.000 23.80024  ? 226 ALA   B CB  1 
ATOM   4571 N N   . ILE   B 1 227 ? -84.29223  -27.13055 -97.35582  1.000 22.70936  ? 227 ILE   B N   1 
ATOM   4572 C CA  . ILE   B 1 227 ? -84.46187  -26.89292 -98.79093  1.000 24.73941  ? 227 ILE   B CA  1 
ATOM   4573 C C   . ILE   B 1 227 ? -85.20789  -28.04936 -99.44619  1.000 26.02880  ? 227 ILE   B C   1 
ATOM   4574 O O   . ILE   B 1 227 ? -86.14476  -27.84909 -100.22979 1.000 30.04262  ? 227 ILE   B O   1 
ATOM   4575 C CB  . ILE   B 1 227 ? -83.09530  -26.65907 -99.45807  1.000 27.77744  ? 227 ILE   B CB  1 
ATOM   4576 C CG1 . ILE   B 1 227 ? -82.50181  -25.33664 -98.98612  1.000 22.94573  ? 227 ILE   B CG1 1 
ATOM   4577 C CG2 . ILE   B 1 227 ? -83.21738  -26.67749 -100.98533 1.000 24.15481  ? 227 ILE   B CG2 1 
ATOM   4578 C CD1 . ILE   B 1 227 ? -81.13168  -25.07729 -99.55715  1.000 21.92088  ? 227 ILE   B CD1 1 
ATOM   4579 N N   . GLU   B 1 228 ? -84.81039  -29.27926 -99.13506  1.000 29.59948  ? 228 GLU   B N   1 
ATOM   4580 C CA  . GLU   B 1 228 ? -85.49390  -30.42335 -99.72961  1.000 34.64550  ? 228 GLU   B CA  1 
ATOM   4581 C C   . GLU   B 1 228 ? -86.91506  -30.54192 -99.20115  1.000 26.78973  ? 228 GLU   B C   1 
ATOM   4582 O O   . GLU   B 1 228 ? -87.86423  -30.73752 -99.97189  1.000 26.73605  ? 228 GLU   B O   1 
ATOM   4583 C CB  . GLU   B 1 228 ? -84.70016  -31.69597 -99.46227  1.000 34.66898  ? 228 GLU   B CB  1 
ATOM   4584 C CG  . GLU   B 1 228 ? -83.29052  -31.61792 -100.01718 1.000 41.47455  ? 228 GLU   B CG  1 
ATOM   4585 C CD  . GLU   B 1 228 ? -82.64433  -32.97236 -100.13748 1.000 48.07182  ? 228 GLU   B CD  1 
ATOM   4586 O OE1 . GLU   B 1 228 ? -82.97628  -33.86114 -99.31954  1.000 47.72462  ? 228 GLU   B OE1 1 
ATOM   4587 O OE2 . GLU   B 1 228 ? -81.81336  -33.14314 -101.05510 1.000 40.02143  ? 228 GLU   B OE2 1 
ATOM   4588 N N   . ARG   B 1 229 ? -87.07926  -30.39897 -97.88616  1.000 24.09615  ? 229 ARG   B N   1 
ATOM   4589 C CA  . ARG   B 1 229 ? -88.40619  -30.46282 -97.28820  1.000 23.19284  ? 229 ARG   B CA  1 
ATOM   4590 C C   . ARG   B 1 229 ? -89.34613  -29.45009 -97.93892  1.000 29.77461  ? 229 ARG   B C   1 
ATOM   4591 O O   . ARG   B 1 229 ? -90.45966  -29.78907 -98.34631  1.000 29.04173  ? 229 ARG   B O   1 
ATOM   4592 C CB  . ARG   B 1 229 ? -88.29339  -30.23303 -95.77943  1.000 28.19146  ? 229 ARG   B CB  1 
ATOM   4593 C CG  . ARG   B 1 229 ? -89.56625  -30.48165 -94.97585  1.000 31.38680  ? 229 ARG   B CG  1 
ATOM   4594 C CD  . ARG   B 1 229 ? -90.14254  -31.86608 -95.23595  1.000 29.41655  ? 229 ARG   B CD  1 
ATOM   4595 N NE  . ARG   B 1 229 ? -90.94617  -32.32159 -94.10429  1.000 35.35100  ? 229 ARG   B NE  1 
ATOM   4596 C CZ  . ARG   B 1 229 ? -91.87644  -33.26709 -94.18187  1.000 31.88427  ? 229 ARG   B CZ  1 
ATOM   4597 N NH1 . ARG   B 1 229 ? -92.11595  -33.86215 -95.33920  1.000 27.14452  ? 229 ARG   B NH1 1 
ATOM   4598 N NH2 . ARG   B 1 229 ? -92.56844  -33.61175 -93.10430  1.000 28.36644  ? 229 ARG   B NH2 1 
ATOM   4599 N N   . TYR   B 1 230 ? -88.89584  -28.20549 -98.08131  1.000 26.78282  ? 230 TYR   B N   1 
ATOM   4600 C CA  . TYR   B 1 230 ? -89.75783  -27.17837 -98.65029  1.000 27.21029  ? 230 TYR   B CA  1 
ATOM   4601 C C   . TYR   B 1 230 ? -89.99407  -27.41610 -100.13880 1.000 33.09652  ? 230 TYR   B C   1 
ATOM   4602 O O   . TYR   B 1 230 ? -91.13098  -27.29887 -100.62084 1.000 25.77960  ? 230 TYR   B O   1 
ATOM   4603 C CB  . TYR   B 1 230 ? -89.14773  -25.79824 -98.40271  1.000 26.60964  ? 230 TYR   B CB  1 
ATOM   4604 C CG  . TYR   B 1 230 ? -89.15373  -25.38625 -96.94369  1.000 23.27239  ? 230 TYR   B CG  1 
ATOM   4605 C CD1 . TYR   B 1 230 ? -90.25327  -25.66228 -96.12652  1.000 18.27470  ? 230 TYR   B CD1 1 
ATOM   4606 C CD2 . TYR   B 1 230 ? -88.05326  -24.72328 -96.37845  1.000 21.56789  ? 230 TYR   B CD2 1 
ATOM   4607 C CE1 . TYR   B 1 230 ? -90.26336  -25.28112 -94.77911  1.000 24.79120  ? 230 TYR   B CE1 1 
ATOM   4608 C CE2 . TYR   B 1 230 ? -88.04951  -24.33215 -95.02574  1.000 17.47511  ? 230 TYR   B CE2 1 
ATOM   4609 C CZ  . TYR   B 1 230 ? -89.15418  -24.61274 -94.23152  1.000 25.88616  ? 230 TYR   B CZ  1 
ATOM   4610 O OH  . TYR   B 1 230 ? -89.15439  -24.23415 -92.89531  1.000 22.11520  ? 230 TYR   B OH  1 
ATOM   4611 N N   . ALA   B 1 231 ? -88.93294  -27.75779 -100.87998 1.000 31.81675  ? 231 ALA   B N   1 
ATOM   4612 C CA  . ALA   B 1 231 ? -89.07270  -28.00355 -102.31131 1.000 29.65872  ? 231 ALA   B CA  1 
ATOM   4613 C C   . ALA   B 1 231 ? -90.04081  -29.14353 -102.59772 1.000 30.05976  ? 231 ALA   B C   1 
ATOM   4614 O O   . ALA   B 1 231 ? -90.74171  -29.12175 -103.61816 1.000 27.48971  ? 231 ALA   B O   1 
ATOM   4615 C CB  . ALA   B 1 231 ? -87.70788  -28.30715 -102.92742 1.000 27.44006  ? 231 ALA   B CB  1 
ATOM   4616 N N   . SER   B 1 232 ? -90.10005  -30.14491 -101.71285 1.000 32.08996  ? 232 SER   B N   1 
ATOM   4617 C CA  . SER   B 1 232 ? -91.00293  -31.26350 -101.94381 1.000 33.09662  ? 232 SER   B CA  1 
ATOM   4618 C C   . SER   B 1 232 ? -92.44851  -30.80470 -102.07022 1.000 33.48987  ? 232 SER   B C   1 
ATOM   4619 O O   . SER   B 1 232 ? -93.26717  -31.53463 -102.63632 1.000 40.15484  ? 232 SER   B O   1 
ATOM   4620 C CB  . SER   B 1 232 ? -90.85733  -32.30208 -100.82922 1.000 29.84285  ? 232 SER   B CB  1 
ATOM   4621 O OG  . SER   B 1 232 ? -91.52115  -31.88970 -99.65078  1.000 32.98295  ? 232 SER   B OG  1 
ATOM   4622 N N   . LEU   B 1 233 ? -92.77405  -29.60272 -101.58712 1.000 34.75226  ? 233 LEU   B N   1 
ATOM   4623 C CA  . LEU   B 1 233 ? -94.10924  -29.03972 -101.74766 1.000 32.41741  ? 233 LEU   B CA  1 
ATOM   4624 C C   . LEU   B 1 233 ? -94.35056  -28.46736 -103.14079 1.000 31.16473  ? 233 LEU   B C   1 
ATOM   4625 O O   . LEU   B 1 233 ? -95.47161  -28.03788 -103.42940 1.000 33.10014  ? 233 LEU   B O   1 
ATOM   4626 C CB  . LEU   B 1 233 ? -94.35133  -27.95111 -100.69767 1.000 28.75520  ? 233 LEU   B CB  1 
ATOM   4627 C CG  . LEU   B 1 233 ? -94.53725  -28.37851 -99.24151  1.000 35.04628  ? 233 LEU   B CG  1 
ATOM   4628 C CD1 . LEU   B 1 233 ? -94.61087  -27.15435 -98.35525  1.000 36.15060  ? 233 LEU   B CD1 1 
ATOM   4629 C CD2 . LEU   B 1 233 ? -95.78545  -29.22519 -99.04959  1.000 29.52803  ? 233 LEU   B CD2 1 
ATOM   4630 N N   . GLY   B 1 234 ? -93.34262  -28.44551 -104.00991 1.000 27.53078  ? 234 GLY   B N   1 
ATOM   4631 C CA  . GLY   B 1 234 ? -93.54441  -27.91037 -105.34072 1.000 23.98196  ? 234 GLY   B CA  1 
ATOM   4632 C C   . GLY   B 1 234 ? -93.61844  -26.40273 -105.41861 1.000 35.28395  ? 234 GLY   B C   1 
ATOM   4633 O O   . GLY   B 1 234 ? -94.01246  -25.87031 -106.46227 1.000 33.21326  ? 234 GLY   B O   1 
ATOM   4634 N N   . VAL   B 1 235 ? -93.25678  -25.69941 -104.33894 1.000 31.76889  ? 235 VAL   B N   1 
ATOM   4635 C CA  . VAL   B 1 235 ? -93.23098  -24.24339 -104.30962 1.000 23.05969  ? 235 VAL   B CA  1 
ATOM   4636 C C   . VAL   B 1 235 ? -91.87335  -23.77423 -104.80685 1.000 21.79534  ? 235 VAL   B C   1 
ATOM   4637 O O   . VAL   B 1 235 ? -90.88953  -24.51640 -104.78660 1.000 26.15636  ? 235 VAL   B O   1 
ATOM   4638 C CB  . VAL   B 1 235 ? -93.50077  -23.70868 -102.88408 1.000 28.28601  ? 235 VAL   B CB  1 
ATOM   4639 C CG1 . VAL   B 1 235 ? -94.95576  -23.92969 -102.48185 1.000 23.61258  ? 235 VAL   B CG1 1 
ATOM   4640 C CG2 . VAL   B 1 235 ? -92.54133  -24.36141 -101.87321 1.000 27.19803  ? 235 VAL   B CG2 1 
ATOM   4641 N N   . VAL   B 1 236 ? -91.81336  -22.52972 -105.25370 1.000 22.47802  ? 236 VAL   B N   1 
ATOM   4642 C CA  . VAL   B 1 236 ? -90.52977  -21.90121 -105.54392 1.000 29.91528  ? 236 VAL   B CA  1 
ATOM   4643 C C   . VAL   B 1 236 ? -89.91086  -21.43992 -104.22533 1.000 24.75088  ? 236 VAL   B C   1 
ATOM   4644 O O   . VAL   B 1 236 ? -90.61990  -21.16786 -103.25024 1.000 25.82881  ? 236 VAL   B O   1 
ATOM   4645 C CB  . VAL   B 1 236 ? -90.71467  -20.74517 -106.55506 1.000 31.83283  ? 236 VAL   B CB  1 
ATOM   4646 C CG1 . VAL   B 1 236 ? -91.86692  -19.88387 -106.16253 1.000 31.68777  ? 236 VAL   B CG1 1 
ATOM   4647 C CG2 . VAL   B 1 236 ? -89.45538  -19.88899 -106.68536 1.000 37.96875  ? 236 VAL   B CG2 1 
ATOM   4648 N N   . LEU   B 1 237 ? -88.57800  -21.39354 -104.16700 1.000 26.18891  ? 237 LEU   B N   1 
ATOM   4649 C CA  . LEU   B 1 237 ? -87.84693  -21.02087 -102.95969 1.000 21.25565  ? 237 LEU   B CA  1 
ATOM   4650 C C   . LEU   B 1 237 ? -87.06914  -19.73183 -103.18233 1.000 20.09121  ? 237 LEU   B C   1 
ATOM   4651 O O   . LEU   B 1 237 ? -86.30032  -19.61843 -104.14604 1.000 20.53707  ? 237 LEU   B O   1 
ATOM   4652 C CB  . LEU   B 1 237 ? -86.87765  -22.12280 -102.53899 1.000 19.45574  ? 237 LEU   B CB  1 
ATOM   4653 C CG  . LEU   B 1 237 ? -87.30324  -23.10274 -101.46028 1.000 25.66557  ? 237 LEU   B CG  1 
ATOM   4654 C CD1 . LEU   B 1 237 ? -88.63248  -23.69779 -101.79162 1.000 28.79478  ? 237 LEU   B CD1 1 
ATOM   4655 C CD2 . LEU   B 1 237 ? -86.25033  -24.20300 -101.31332 1.000 30.04422  ? 237 LEU   B CD2 1 
ATOM   4656 N N   . HIS   B 1 238 ? -87.24533  -18.78054 -102.27085 1.000 19.18839  ? 238 HIS   B N   1 
ATOM   4657 C CA  . HIS   B 1 238 ? -86.44697  -17.56089 -102.21616 1.000 19.85960  ? 238 HIS   B CA  1 
ATOM   4658 C C   . HIS   B 1 238 ? -85.73213  -17.48933 -100.87296 1.000 18.62979  ? 238 HIS   B C   1 
ATOM   4659 O O   . HIS   B 1 238 ? -86.35889  -17.67976 -99.82320  1.000 22.63683  ? 238 HIS   B O   1 
ATOM   4660 C CB  . HIS   B 1 238 ? -87.32437  -16.31402 -102.38617 1.000 17.35161  ? 238 HIS   B CB  1 
ATOM   4661 C CG  . HIS   B 1 238 ? -87.76854  -16.06844 -103.79191 1.000 22.47023  ? 238 HIS   B CG  1 
ATOM   4662 N ND1 . HIS   B 1 238 ? -88.36004  -14.88714 -104.18767 1.000 24.90148  ? 238 HIS   B ND1 1 
ATOM   4663 C CD2 . HIS   B 1 238 ? -87.71637  -16.85193 -104.89592 1.000 25.25713  ? 238 HIS   B CD2 1 
ATOM   4664 C CE1 . HIS   B 1 238 ? -88.65723  -14.95552 -105.47412 1.000 25.65125  ? 238 HIS   B CE1 1 
ATOM   4665 N NE2 . HIS   B 1 238 ? -88.27680  -16.13725 -105.92775 1.000 27.58060  ? 238 HIS   B NE2 1 
ATOM   4666 N N   . ILE   B 1 239 ? -84.43196  -17.21895 -100.90136 1.000 19.25210  ? 239 ILE   B N   1 
ATOM   4667 C CA  . ILE   B 1 239 ? -83.73195  -16.74784 -99.70999  1.000 12.03788  ? 239 ILE   B CA  1 
ATOM   4668 C C   . ILE   B 1 239 ? -83.95301  -15.23945 -99.65068  1.000 14.92817  ? 239 ILE   B C   1 
ATOM   4669 O O   . ILE   B 1 239 ? -83.55597  -14.51383 -100.56836 1.000 15.26040  ? 239 ILE   B O   1 
ATOM   4670 C CB  . ILE   B 1 239 ? -82.23411  -17.09708 -99.76292  1.000 19.95462  ? 239 ILE   B CB  1 
ATOM   4671 C CG1 . ILE   B 1 239 ? -82.01822  -18.58785 -100.05307 1.000 21.83734  ? 239 ILE   B CG1 1 
ATOM   4672 C CG2 . ILE   B 1 239 ? -81.54286  -16.71640 -98.46127  1.000 11.55043  ? 239 ILE   B CG2 1 
ATOM   4673 C CD1 . ILE   B 1 239 ? -82.82110  -19.51217 -99.15301  1.000 19.47585  ? 239 ILE   B CD1 1 
ATOM   4674 N N   . THR   B 1 240 ? -84.61082  -14.75797 -98.58799  1.000 14.87366  ? 240 THR   B N   1 
ATOM   4675 C CA  . THR   B 1 240 ? -85.16063  -13.40720 -98.63473  1.000 16.78940  ? 240 THR   B CA  1 
ATOM   4676 C C   . THR   B 1 240 ? -84.42945  -12.37178 -97.79878  1.000 16.40757  ? 240 THR   B C   1 
ATOM   4677 O O   . THR   B 1 240 ? -84.56399  -11.17850 -98.08471  1.000 18.44757  ? 240 THR   B O   1 
ATOM   4678 C CB  . THR   B 1 240 ? -86.63197  -13.40601 -98.20828  1.000 13.14099  ? 240 THR   B CB  1 
ATOM   4679 O OG1 . THR   B 1 240 ? -86.77124  -14.08927 -96.96082  1.000 14.41895  ? 240 THR   B OG1 1 
ATOM   4680 C CG2 . THR   B 1 240 ? -87.45969  -14.10137 -99.25325  1.000 14.86111  ? 240 THR   B CG2 1 
ATOM   4681 N N   . GLY   B 1 241 ? -83.68261  -12.76942 -96.78204  1.000 14.74558  ? 241 GLY   B N   1 
ATOM   4682 C CA  . GLY   B 1 241 ? -82.98878  -11.76202 -96.00009  1.000 16.90842  ? 241 GLY   B CA  1 
ATOM   4683 C C   . GLY   B 1 241 ? -81.66398  -12.23412 -95.44043  1.000 21.38469  ? 241 GLY   B C   1 
ATOM   4684 O O   . GLY   B 1 241 ? -81.38503  -12.07553 -94.24401  1.000 16.02149  ? 241 GLY   B O   1 
ATOM   4685 N N   . LEU   B 1 242 ? -80.84226  -12.82657 -96.30334  1.000 20.55934  ? 242 LEU   B N   1 
ATOM   4686 C CA  . LEU   B 1 242 ? -79.64728  -13.51262 -95.83817  1.000 14.81536  ? 242 LEU   B CA  1 
ATOM   4687 C C   . LEU   B 1 242 ? -78.67579  -12.53562 -95.18500  1.000 18.06235  ? 242 LEU   B C   1 
ATOM   4688 O O   . LEU   B 1 242 ? -78.36871  -11.47453 -95.73680  1.000 16.43918  ? 242 LEU   B O   1 
ATOM   4689 C CB  . LEU   B 1 242 ? -78.97952  -14.24107 -97.00217  1.000 14.66415  ? 242 LEU   B CB  1 
ATOM   4690 C CG  . LEU   B 1 242 ? -77.54816  -14.76369 -96.80957  1.000 27.88589  ? 242 LEU   B CG  1 
ATOM   4691 C CD1 . LEU   B 1 242 ? -77.50307  -15.91235 -95.79138  1.000 16.29518  ? 242 LEU   B CD1 1 
ATOM   4692 C CD2 . LEU   B 1 242 ? -76.93785  -15.18328 -98.15126  1.000 15.13519  ? 242 LEU   B CD2 1 
ATOM   4693 N N   . ASP   B 1 243 ? -78.23684  -12.88093 -93.97769  1.000 14.67542  ? 243 ASP   B N   1 
ATOM   4694 C CA  . ASP   B 1 243 ? -77.03196  -12.31102 -93.39779  1.000 15.32298  ? 243 ASP   B CA  1 
ATOM   4695 C C   . ASP   B 1 243 ? -76.39433  -13.37387 -92.50812  1.000 16.64933  ? 243 ASP   B C   1 
ATOM   4696 O O   . ASP   B 1 243 ? -77.04850  -14.33213 -92.08112  1.000 19.41444  ? 243 ASP   B O   1 
ATOM   4697 C CB  . ASP   B 1 243 ? -77.28758  -11.00267 -92.62218  1.000 14.90218  ? 243 ASP   B CB  1 
ATOM   4698 C CG  . ASP   B 1 243 ? -78.64263  -10.96631 -91.88314  1.000 22.33351  ? 243 ASP   B CG  1 
ATOM   4699 O OD1 . ASP   B 1 243 ? -79.14673  -12.02746 -91.42745  1.000 17.03824  ? 243 ASP   B OD1 1 
ATOM   4700 O OD2 . ASP   B 1 243 ? -79.19279  -9.83923  -91.73946  1.000 16.86417  ? 243 ASP   B OD2 1 
ATOM   4701 N N   . VAL   B 1 244 ? -75.09238  -13.22689 -92.27848  1.000 15.39441  ? 244 VAL   B N   1 
ATOM   4702 C CA  . VAL   B 1 244 ? -74.32189  -14.16166 -91.45901  1.000 15.59398  ? 244 VAL   B CA  1 
ATOM   4703 C C   . VAL   B 1 244 ? -73.72106  -13.35905 -90.31183  1.000 16.23822  ? 244 VAL   B C   1 
ATOM   4704 O O   . VAL   B 1 244 ? -72.71634  -12.65671 -90.48943  1.000 11.95503  ? 244 VAL   B O   1 
ATOM   4705 C CB  . VAL   B 1 244 ? -73.25880  -14.90318 -92.27684  1.000 15.63434  ? 244 VAL   B CB  1 
ATOM   4706 C CG1 . VAL   B 1 244 ? -72.47652  -15.87587 -91.40287  1.000 17.44765  ? 244 VAL   B CG1 1 
ATOM   4707 C CG2 . VAL   B 1 244 ? -73.94661  -15.68817 -93.38101  1.000 10.75288  ? 244 VAL   B CG2 1 
ATOM   4708 N N   . SER   B 1 245 ? -74.36164  -13.43202 -89.13988  1.000 12.92595  ? 245 SER   B N   1 
ATOM   4709 C CA  . SER   B 1 245 ? -73.93992  -12.63699 -87.99242  1.000 14.47383  ? 245 SER   B CA  1 
ATOM   4710 C C   . SER   B 1 245 ? -72.61023  -13.12663 -87.43168  1.000 16.59985  ? 245 SER   B C   1 
ATOM   4711 O O   . SER   B 1 245 ? -72.37677  -14.33410 -87.30433  1.000 14.62354  ? 245 SER   B O   1 
ATOM   4712 C CB  . SER   B 1 245 ? -74.98856  -12.69847 -86.88616  1.000 16.31687  ? 245 SER   B CB  1 
ATOM   4713 O OG  . SER   B 1 245 ? -74.49908  -12.05973 -85.71145  1.000 16.72868  ? 245 SER   B OG  1 
ATOM   4714 N N   . MET   B 1 246 ? -71.74403  -12.17585 -87.07759  1.000 11.08861  ? 246 MET   B N   1 
ATOM   4715 C CA  . MET   B 1 246 ? -70.51212  -12.51659 -86.37517  1.000 21.27248  ? 246 MET   B CA  1 
ATOM   4716 C C   . MET   B 1 246 ? -70.76094  -13.01784 -84.95383  1.000 24.60471  ? 246 MET   B C   1 
ATOM   4717 O O   . MET   B 1 246 ? -69.83912  -13.56173 -84.33949  1.000 27.29742  ? 246 MET   B O   1 
ATOM   4718 C CB  . MET   B 1 246 ? -69.55145  -11.31327 -86.33281  1.000 17.58863  ? 246 MET   B CB  1 
ATOM   4719 C CG  . MET   B 1 246 ? -68.99076  -10.87267 -87.70903  1.000 17.22771  ? 246 MET   B CG  1 
ATOM   4720 S SD  . MET   B 1 246 ? -68.18805  -12.21669 -88.62007  1.000 20.43675  ? 246 MET   B SD  1 
ATOM   4721 C CE  . MET   B 1 246 ? -67.17794  -11.29610 -89.77380  1.000 16.00875  ? 246 MET   B CE  1 
ATOM   4722 N N   . PHE   B 1 247 ? -71.96996  -12.86607 -84.42196  1.000 20.92752  ? 247 PHE   B N   1 
ATOM   4723 C CA  . PHE   B 1 247 ? -72.29814  -13.32219 -83.07773  1.000 22.27110  ? 247 PHE   B CA  1 
ATOM   4724 C C   . PHE   B 1 247 ? -73.38172  -14.38361 -83.13730  1.000 20.17016  ? 247 PHE   B C   1 
ATOM   4725 O O   . PHE   B 1 247 ? -74.35057  -14.25032 -83.89317  1.000 20.68192  ? 247 PHE   B O   1 
ATOM   4726 C CB  . PHE   B 1 247 ? -72.76634  -12.15488 -82.19283  1.000 15.76180  ? 247 PHE   B CB  1 
ATOM   4727 C CG  . PHE   B 1 247 ? -71.84133  -10.98875 -82.21420  1.000 19.56161  ? 247 PHE   B CG  1 
ATOM   4728 C CD1 . PHE   B 1 247 ? -70.65990  -11.00884 -81.46709  1.000 14.53415  ? 247 PHE   B CD1 1 
ATOM   4729 C CD2 . PHE   B 1 247 ? -72.12277  -9.87607  -83.00644  1.000 17.49132  ? 247 PHE   B CD2 1 
ATOM   4730 C CE1 . PHE   B 1 247 ? -69.78458  -9.91776  -81.49069  1.000 17.83408  ? 247 PHE   B CE1 1 
ATOM   4731 C CE2 . PHE   B 1 247 ? -71.25220  -8.77853  -83.03793  1.000 21.23908  ? 247 PHE   B CE2 1 
ATOM   4732 C CZ  . PHE   B 1 247 ? -70.07674  -8.79993  -82.27919  1.000 19.53317  ? 247 PHE   B CZ  1 
ATOM   4733 N N   . GLU   B 1 248 ? -73.22446  -15.43463 -82.33844  1.000 18.00827  ? 248 GLU   B N   1 
ATOM   4734 C CA  . GLU   B 1 248 ? -74.34589  -16.34063 -82.13938  1.000 21.07421  ? 248 GLU   B CA  1 
ATOM   4735 C C   . GLU   B 1 248 ? -75.46825  -15.58057 -81.44091  1.000 24.51354  ? 248 GLU   B C   1 
ATOM   4736 O O   . GLU   B 1 248 ? -75.22954  -14.58622 -80.74827  1.000 17.83177  ? 248 GLU   B O   1 
ATOM   4737 C CB  . GLU   B 1 248 ? -73.92238  -17.56612 -81.33009  1.000 23.47917  ? 248 GLU   B CB  1 
ATOM   4738 C CG  . GLU   B 1 248 ? -72.76439  -18.35247 -81.95625  1.000 28.59381  ? 248 GLU   B CG  1 
ATOM   4739 C CD  . GLU   B 1 248 ? -73.18287  -19.14595 -83.18012  1.000 26.69074  ? 248 GLU   B CD  1 
ATOM   4740 O OE1 . GLU   B 1 248 ? -72.30426  -19.51207 -83.98819  1.000 22.72115  ? 248 GLU   B OE1 1 
ATOM   4741 O OE2 . GLU   B 1 248 ? -74.39887  -19.39729 -83.33677  1.000 28.48520  ? 248 GLU   B OE2 1 
ATOM   4742 N N   . PHE   B 1 249 ? -76.70847  -16.03540 -81.65348  1.000 23.18236  ? 249 PHE   B N   1 
ATOM   4743 C CA  . PHE   B 1 249 ? -77.85366  -15.20183 -81.30613  1.000 26.87275  ? 249 PHE   B CA  1 
ATOM   4744 C C   . PHE   B 1 249 ? -77.87373  -14.86032 -79.81700  1.000 27.64742  ? 249 PHE   B C   1 
ATOM   4745 O O   . PHE   B 1 249 ? -78.18570  -13.72195 -79.44176  1.000 24.11708  ? 249 PHE   B O   1 
ATOM   4746 C CB  . PHE   B 1 249 ? -79.16131  -15.87910 -81.72821  1.000 33.21191  ? 249 PHE   B CB  1 
ATOM   4747 C CG  . PHE   B 1 249 ? -80.34390  -14.95891 -81.67388  1.000 30.70978  ? 249 PHE   B CG  1 
ATOM   4748 C CD1 . PHE   B 1 249 ? -80.45580  -13.89751 -82.57240  1.000 39.33829  ? 249 PHE   B CD1 1 
ATOM   4749 C CD2 . PHE   B 1 249 ? -81.31753  -15.11144 -80.69239  1.000 36.04712  ? 249 PHE   B CD2 1 
ATOM   4750 C CE1 . PHE   B 1 249 ? -81.54384  -13.01578 -82.50821  1.000 42.77838  ? 249 PHE   B CE1 1 
ATOM   4751 C CE2 . PHE   B 1 249 ? -82.40513  -14.23765 -80.62177  1.000 34.59534  ? 249 PHE   B CE2 1 
ATOM   4752 C CZ  . PHE   B 1 249 ? -82.51610  -13.18858 -81.53034  1.000 38.05329  ? 249 PHE   B CZ  1 
ATOM   4753 N N   . HIS   B 1 250 ? -77.50358  -15.81683 -78.96068  1.000 23.21565  ? 250 HIS   B N   1 
ATOM   4754 C CA  . HIS   B 1 250 ? -77.46091  -15.60031 -77.51865  1.000 29.59196  ? 250 HIS   B CA  1 
ATOM   4755 C C   . HIS   B 1 250 ? -76.23330  -14.82423 -77.04567  1.000 29.86434  ? 250 HIS   B C   1 
ATOM   4756 O O   . HIS   B 1 250 ? -76.16103  -14.50109 -75.85037  1.000 24.77620  ? 250 HIS   B O   1 
ATOM   4757 C CB  . HIS   B 1 250 ? -77.51631  -16.94605 -76.78440  1.000 26.36600  ? 250 HIS   B CB  1 
ATOM   4758 C CG  . HIS   B 1 250 ? -78.84226  -17.63200 -76.88307  1.000 47.51819  ? 250 HIS   B CG  1 
ATOM   4759 N ND1 . HIS   B 1 250 ? -79.79284  -17.56677 -75.88553  1.000 48.41819  ? 250 HIS   B ND1 1 
ATOM   4760 C CD2 . HIS   B 1 250 ? -79.38594  -18.38154 -77.87210  1.000 53.78666  ? 250 HIS   B CD2 1 
ATOM   4761 C CE1 . HIS   B 1 250 ? -80.86036  -18.25551 -76.25181  1.000 47.21079  ? 250 HIS   B CE1 1 
ATOM   4762 N NE2 . HIS   B 1 250 ? -80.64048  -18.75730 -77.45449  1.000 50.29778  ? 250 HIS   B NE2 1 
ATOM   4763 N N   . ASP   B 1 251 ? -75.27192  -14.52895 -77.92981  1.000 17.82040  ? 251 ASP   B N   1 
ATOM   4764 C CA  . ASP   B 1 251 ? -74.06656  -13.78989 -77.56081  1.000 15.35514  ? 251 ASP   B CA  1 
ATOM   4765 C C   . ASP   B 1 251 ? -74.33819  -12.28925 -77.63970  1.000 19.28008  ? 251 ASP   B C   1 
ATOM   4766 O O   . ASP   B 1 251 ? -74.38817  -11.72529 -78.73247  1.000 17.56145  ? 251 ASP   B O   1 
ATOM   4767 C CB  . ASP   B 1 251 ? -72.89649  -14.16399 -78.46871  1.000 17.90479  ? 251 ASP   B CB  1 
ATOM   4768 C CG  . ASP   B 1 251 ? -71.58515  -13.46468 -78.06603  1.000 23.35860  ? 251 ASP   B CG  1 
ATOM   4769 O OD1 . ASP   B 1 251 ? -71.60646  -12.58517 -77.17343  1.000 24.44163  ? 251 ASP   B OD1 1 
ATOM   4770 O OD2 . ASP   B 1 251 ? -70.52261  -13.78799 -78.63569  1.000 18.07892  ? 251 ASP   B OD2 1 
ATOM   4771 N N   . ARG   B 1 252 ? -74.44713  -11.62570 -76.48270  1.000 18.70578  ? 252 ARG   B N   1 
ATOM   4772 C CA  . ARG   B 1 252 ? -74.72084  -10.19439 -76.43168  1.000 22.80232  ? 252 ARG   B CA  1 
ATOM   4773 C C   . ARG   B 1 252 ? -73.48424  -9.35559  -76.09246  1.000 24.77778  ? 252 ARG   B C   1 
ATOM   4774 O O   . ARG   B 1 252 ? -73.62463  -8.20580  -75.64875  1.000 21.02599  ? 252 ARG   B O   1 
ATOM   4775 C CB  . ARG   B 1 252 ? -75.83493  -9.90895  -75.42526  1.000 23.95876  ? 252 ARG   B CB  1 
ATOM   4776 C CG  . ARG   B 1 252 ? -75.60168  -10.56909 -74.09281  1.000 27.14016  ? 252 ARG   B CG  1 
ATOM   4777 C CD  . ARG   B 1 252 ? -76.76745  -10.37171 -73.13688  1.000 31.78069  ? 252 ARG   B CD  1 
ATOM   4778 N NE  . ARG   B 1 252 ? -76.40462  -10.82952 -71.79819  1.000 33.38383  ? 252 ARG   B NE  1 
ATOM   4779 C CZ  . ARG   B 1 252 ? -76.95614  -11.86139 -71.16422  1.000 44.06231  ? 252 ARG   B CZ  1 
ATOM   4780 N NH1 . ARG   B 1 252 ? -77.94531  -12.56850 -71.72979  1.000 48.15707  ? 252 ARG   B NH1 1 
ATOM   4781 N NH2 . ARG   B 1 252 ? -76.51025  -12.16699 -69.94349  1.000 27.45479  ? 252 ARG   B NH2 1 
ATOM   4782 N N   . ARG   B 1 253 ? -72.28400  -9.89444  -76.30245  1.000 16.27951  ? 253 ARG   B N   1 
ATOM   4783 C CA  . ARG   B 1 253 ? -71.07240  -9.13819  -76.01487  1.000 19.10328  ? 253 ARG   B CA  1 
ATOM   4784 C C   . ARG   B 1 253 ? -71.02622  -7.84894  -76.83015  1.000 20.66129  ? 253 ARG   B C   1 
ATOM   4785 O O   . ARG   B 1 253 ? -71.44793  -7.80898  -77.98651  1.000 24.76337  ? 253 ARG   B O   1 
ATOM   4786 C CB  . ARG   B 1 253 ? -69.83046  -9.99558  -76.29607  1.000 24.40893  ? 253 ARG   B CB  1 
ATOM   4787 C CG  . ARG   B 1 253 ? -69.51397  -10.23350 -77.76769  1.000 22.91810  ? 253 ARG   B CG  1 
ATOM   4788 C CD  . ARG   B 1 253 ? -68.39287  -11.25887 -77.92755  1.000 19.78121  ? 253 ARG   B CD  1 
ATOM   4789 N NE  . ARG   B 1 253 ? -67.16384  -10.81705 -77.27954  1.000 24.20906  ? 253 ARG   B NE  1 
ATOM   4790 C CZ  . ARG   B 1 253 ? -66.19127  -11.62967 -76.87039  1.000 20.54377  ? 253 ARG   B CZ  1 
ATOM   4791 N NH1 . ARG   B 1 253 ? -66.29722  -12.93802 -77.03759  1.000 21.23118  ? 253 ARG   B NH1 1 
ATOM   4792 N NH2 . ARG   B 1 253 ? -65.12232  -11.13322 -76.26530  1.000 20.32238  ? 253 ARG   B NH2 1 
ATOM   4793 N N   . THR   B 1 254 ? -70.51722  -6.78341  -76.21069  1.000 19.74927  ? 254 THR   B N   1 
ATOM   4794 C CA  . THR   B 1 254 ? -70.45879  -5.46282  -76.82465  1.000 15.95750  ? 254 THR   B CA  1 
ATOM   4795 C C   . THR   B 1 254 ? -69.04529  -4.90401  -76.88056  1.000 18.24685  ? 254 THR   B C   1 
ATOM   4796 O O   . THR   B 1 254 ? -68.87639  -3.70965  -77.15311  1.000 18.51678  ? 254 THR   B O   1 
ATOM   4797 C CB  . THR   B 1 254 ? -71.36154  -4.47797  -76.06912  1.000 24.03075  ? 254 THR   B CB  1 
ATOM   4798 O OG1 . THR   B 1 254 ? -71.00677  -4.46329  -74.67643  1.000 23.88004  ? 254 THR   B OG1 1 
ATOM   4799 C CG2 . THR   B 1 254 ? -72.81829  -4.87386  -76.20974  1.000 18.05152  ? 254 THR   B CG2 1 
ATOM   4800 N N   . ASP   B 1 255 ? -68.02771  -5.73603  -76.65945  1.000 16.87966  ? 255 ASP   B N   1 
ATOM   4801 C CA  . ASP   B 1 255 ? -66.65780  -5.26972  -76.51031  1.000 22.02666  ? 255 ASP   B CA  1 
ATOM   4802 C C   . ASP   B 1 255 ? -65.89300  -5.16199  -77.82685  1.000 24.73460  ? 255 ASP   B C   1 
ATOM   4803 O O   . ASP   B 1 255 ? -64.76005  -4.67000  -77.82126  1.000 23.87674  ? 255 ASP   B O   1 
ATOM   4804 C CB  . ASP   B 1 255 ? -65.89357  -6.19430  -75.55121  1.000 19.70083  ? 255 ASP   B CB  1 
ATOM   4805 C CG  . ASP   B 1 255 ? -65.92942  -7.64028  -75.98817  1.000 23.76557  ? 255 ASP   B CG  1 
ATOM   4806 O OD1 . ASP   B 1 255 ? -67.02646  -8.12321  -76.35655  1.000 22.92978  ? 255 ASP   B OD1 1 
ATOM   4807 O OD2 . ASP   B 1 255 ? -64.86453  -8.29642  -75.96353  1.000 25.67023  ? 255 ASP   B OD2 1 
ATOM   4808 N N   . LEU   B 1 256 ? -66.46699  -5.58252  -78.94932  1.000 24.15770  ? 256 LEU   B N   1 
ATOM   4809 C CA  . LEU   B 1 256 ? -65.71287  -5.69000  -80.19533  1.000 26.36187  ? 256 LEU   B CA  1 
ATOM   4810 C C   . LEU   B 1 256 ? -65.90249  -4.43137  -81.02855  1.000 23.35270  ? 256 LEU   B C   1 
ATOM   4811 O O   . LEU   B 1 256 ? -67.02695  -4.10451  -81.41349  1.000 28.78590  ? 256 LEU   B O   1 
ATOM   4812 C CB  . LEU   B 1 256 ? -66.14048  -6.91987  -80.98875  1.000 21.27878  ? 256 LEU   B CB  1 
ATOM   4813 C CG  . LEU   B 1 256 ? -65.19913  -8.12026  -80.84856  1.000 32.95984  ? 256 LEU   B CG  1 
ATOM   4814 C CD1 . LEU   B 1 256 ? -64.99484  -8.52753  -79.39225  1.000 26.36418  ? 256 LEU   B CD1 1 
ATOM   4815 C CD2 . LEU   B 1 256 ? -65.75755  -9.26153  -81.62691  1.000 25.69732  ? 256 LEU   B CD2 1 
ATOM   4816 N N   . ALA   B 1 257 ? -64.80819  -3.72165  -81.29532  1.000 23.26913  ? 257 ALA   B N   1 
ATOM   4817 C CA  . ALA   B 1 257 ? -64.86204  -2.58625  -82.20761  1.000 27.56204  ? 257 ALA   B CA  1 
ATOM   4818 C C   . ALA   B 1 257 ? -64.67857  -2.99217  -83.66761  1.000 26.80385  ? 257 ALA   B C   1 
ATOM   4819 O O   . ALA   B 1 257 ? -64.97663  -2.19661  -84.56342  1.000 24.58140  ? 257 ALA   B O   1 
ATOM   4820 C CB  . ALA   B 1 257 ? -63.79734  -1.55492  -81.82560  1.000 23.41867  ? 257 ALA   B CB  1 
ATOM   4821 N N   . ALA   B 1 258 ? -64.19906  -4.20695  -83.92030  1.000 21.90315  ? 258 ALA   B N   1 
ATOM   4822 C CA  . ALA   B 1 258 ? -63.94343  -4.72326  -85.25355  1.000 18.91766  ? 258 ALA   B CA  1 
ATOM   4823 C C   . ALA   B 1 258 ? -64.05161  -6.23277  -85.17184  1.000 22.92088  ? 258 ALA   B C   1 
ATOM   4824 O O   . ALA   B 1 258 ? -63.83015  -6.80462  -84.09466  1.000 19.94615  ? 258 ALA   B O   1 
ATOM   4825 C CB  . ALA   B 1 258 ? -62.55331  -4.31995  -85.76196  1.000 14.41208  ? 258 ALA   B CB  1 
ATOM   4826 N N   . PRO   B 1 259 ? -64.39226  -6.90831  -86.26914  1.000 17.73051  ? 259 PRO   B N   1 
ATOM   4827 C CA  . PRO   B 1 259 ? -64.35759  -8.37167  -86.24968  1.000 17.10007  ? 259 PRO   B CA  1 
ATOM   4828 C C   . PRO   B 1 259 ? -62.92318  -8.84764  -86.12811  1.000 21.28145  ? 259 PRO   B C   1 
ATOM   4829 O O   . PRO   B 1 259 ? -61.99224  -8.19654  -86.60636  1.000 23.87853  ? 259 PRO   B O   1 
ATOM   4830 C CB  . PRO   B 1 259 ? -64.96449  -8.76786  -87.60091  1.000 19.71248  ? 259 PRO   B CB  1 
ATOM   4831 C CG  . PRO   B 1 259 ? -64.67971  -7.59294  -88.51248  1.000 15.98131  ? 259 PRO   B CG  1 
ATOM   4832 C CD  . PRO   B 1 259 ? -64.69157  -6.37028  -87.61217  1.000 19.68564  ? 259 PRO   B CD  1 
ATOM   4833 N N   . THR   B 1 260 ? -62.74997  -9.98174  -85.45861  1.000 24.81174  ? 260 THR   B N   1 
ATOM   4834 C CA  . THR   B 1 260 ? -61.45124  -10.63199 -85.37864  1.000 24.06790  ? 260 THR   B CA  1 
ATOM   4835 C C   . THR   B 1 260 ? -61.14389  -11.33444 -86.69162  1.000 27.80481  ? 260 THR   B C   1 
ATOM   4836 O O   . THR   B 1 260 ? -62.03521  -11.63393 -87.48716  1.000 23.56509  ? 260 THR   B O   1 
ATOM   4837 C CB  . THR   B 1 260 ? -61.42576  -11.65800 -84.24851  1.000 23.78390  ? 260 THR   B CB  1 
ATOM   4838 O OG1 . THR   B 1 260 ? -62.34763  -12.71072 -84.55608  1.000 27.92425  ? 260 THR   B OG1 1 
ATOM   4839 C CG2 . THR   B 1 260 ? -61.82534  -11.01142 -82.92576  1.000 25.88416  ? 260 THR   B CG2 1 
ATOM   4840 N N   . SER   B 1 261 ? -59.86460  -11.62187 -86.91421  1.000 26.14869  ? 261 SER   B N   1 
ATOM   4841 C CA  . SER   B 1 261 ? -59.52455  -12.34133 -88.13596  1.000 26.85620  ? 261 SER   B CA  1 
ATOM   4842 C C   . SER   B 1 261 ? -60.14390  -13.72840 -88.12777  1.000 24.40924  ? 261 SER   B C   1 
ATOM   4843 O O   . SER   B 1 261 ? -60.47157  -14.27045 -89.18690  1.000 26.49776  ? 261 SER   B O   1 
ATOM   4844 C CB  . SER   B 1 261 ? -58.00408  -12.41500 -88.31647  1.000 21.58434  ? 261 SER   B CB  1 
ATOM   4845 O OG  . SER   B 1 261 ? -57.39253  -12.96566 -87.17236  1.000 30.28592  ? 261 SER   B OG  1 
ATOM   4846 N N   . GLU   B 1 262 ? -60.33310  -14.31240 -86.94500  1.000 23.98913  ? 262 GLU   B N   1 
ATOM   4847 C CA  . GLU   B 1 262 ? -60.99642  -15.60841 -86.88100  1.000 29.90538  ? 262 GLU   B CA  1 
ATOM   4848 C C   . GLU   B 1 262 ? -62.46072  -15.48773 -87.30562  1.000 29.82116  ? 262 GLU   B C   1 
ATOM   4849 O O   . GLU   B 1 262 ? -62.98701  -16.36695 -88.00690  1.000 26.66271  ? 262 GLU   B O   1 
ATOM   4850 C CB  . GLU   B 1 262 ? -60.85487  -16.18448 -85.46695  1.000 32.78359  ? 262 GLU   B CB  1 
ATOM   4851 C CG  . GLU   B 1 262 ? -61.80811  -17.32057 -85.12392  1.000 42.60202  ? 262 GLU   B CG  1 
ATOM   4852 C CD  . GLU   B 1 262 ? -61.41835  -18.65604 -85.75745  1.000 61.69819  ? 262 GLU   B CD  1 
ATOM   4853 O OE1 . GLU   B 1 262 ? -62.33007  -19.47896 -86.02107  1.000 69.77059  ? 262 GLU   B OE1 1 
ATOM   4854 O OE2 . GLU   B 1 262 ? -60.20797  -18.88615 -85.98274  1.000 60.16406  ? 262 GLU   B OE2 1 
ATOM   4855 N N   . MET   B 1 263 ? -63.12072  -14.39000 -86.90665  1.000 22.15740  ? 263 MET   B N   1 
ATOM   4856 C CA  . MET   B 1 263 ? -64.47127  -14.08751 -87.38177  1.000 20.98768  ? 263 MET   B CA  1 
ATOM   4857 C C   . MET   B 1 263 ? -64.50760  -13.96697 -88.89899  1.000 21.67805  ? 263 MET   B C   1 
ATOM   4858 O O   . MET   B 1 263 ? -65.30051  -14.64085 -89.57117  1.000 23.23639  ? 263 MET   B O   1 
ATOM   4859 C CB  . MET   B 1 263 ? -64.96867  -12.78967 -86.74392  1.000 22.04217  ? 263 MET   B CB  1 
ATOM   4860 C CG  . MET   B 1 263 ? -65.98323  -12.99076 -85.64136  1.000 27.20096  ? 263 MET   B CG  1 
ATOM   4861 S SD  . MET   B 1 263 ? -66.13729  -11.58640 -84.51968  1.000 31.65245  ? 263 MET   B SD  1 
ATOM   4862 C CE  . MET   B 1 263 ? -65.50120  -12.37475 -83.05188  1.000 59.20281  ? 263 MET   B CE  1 
ATOM   4863 N N   . ILE   B 1 264 ? -63.64501  -13.10672 -89.45137  1.000 21.68881  ? 264 ILE   B N   1 
ATOM   4864 C CA  . ILE   B 1 264 ? -63.58931  -12.88286 -90.89234  1.000 19.33037  ? 264 ILE   B CA  1 
ATOM   4865 C C   . ILE   B 1 264 ? -63.39060  -14.19494 -91.63668  1.000 21.59664  ? 264 ILE   B C   1 
ATOM   4866 O O   . ILE   B 1 264 ? -64.08012  -14.48151 -92.62195  1.000 29.25335  ? 264 ILE   B O   1 
ATOM   4867 C CB  . ILE   B 1 264 ? -62.47649  -11.87885 -91.23013  1.000 21.86168  ? 264 ILE   B CB  1 
ATOM   4868 C CG1 . ILE   B 1 264 ? -62.82010  -10.50582 -90.66216  1.000 16.59119  ? 264 ILE   B CG1 1 
ATOM   4869 C CG2 . ILE   B 1 264 ? -62.30648  -11.78534 -92.71798  1.000 14.92549  ? 264 ILE   B CG2 1 
ATOM   4870 C CD1 . ILE   B 1 264 ? -63.96895  -9.85139  -91.38836  1.000 19.80319  ? 264 ILE   B CD1 1 
ATOM   4871 N N   . GLU   B 1 265 ? -62.46263  -15.02260 -91.16511  1.000 17.59789  ? 265 GLU   B N   1 
ATOM   4872 C CA  . GLU   B 1 265 ? -62.10675  -16.21712 -91.92356  1.000 25.04388  ? 265 GLU   B CA  1 
ATOM   4873 C C   . GLU   B 1 265 ? -63.20766  -17.26499 -91.86367  1.000 24.81758  ? 265 GLU   B C   1 
ATOM   4874 O O   . GLU   B 1 265 ? -63.48205  -17.95138 -92.85920  1.000 20.16354  ? 265 GLU   B O   1 
ATOM   4875 C CB  . GLU   B 1 265 ? -60.78164  -16.78729 -91.41436  1.000 19.13307  ? 265 GLU   B CB  1 
ATOM   4876 C CG  . GLU   B 1 265 ? -59.60664  -15.86168 -91.65488  1.000 27.98848  ? 265 GLU   B CG  1 
ATOM   4877 C CD  . GLU   B 1 265 ? -58.34397  -16.25732 -90.89652  1.000 29.83264  ? 265 GLU   B CD  1 
ATOM   4878 O OE1 . GLU   B 1 265 ? -58.33735  -17.28559 -90.17734  1.000 31.80509  ? 265 GLU   B OE1 1 
ATOM   4879 O OE2 . GLU   B 1 265 ? -57.35535  -15.51049 -91.01781  1.000 27.44091  ? 265 GLU   B OE2 1 
ATOM   4880 N N   . ARG   B 1 266 ? -63.84163  -17.41818 -90.70573  1.000 30.15512  ? 266 ARG   B N   1 
ATOM   4881 C CA  . ARG   B 1 266 ? -64.89865  -18.41219 -90.63264  1.000 21.88672  ? 266 ARG   B CA  1 
ATOM   4882 C C   . ARG   B 1 266 ? -66.16826  -17.88577 -91.28492  1.000 21.96201  ? 266 ARG   B C   1 
ATOM   4883 O O   . ARG   B 1 266 ? -66.94817  -18.67007 -91.84154  1.000 23.21537  ? 266 ARG   B O   1 
ATOM   4884 C CB  . ARG   B 1 266 ? -65.12203  -18.84327 -89.17791  1.000 23.97909  ? 266 ARG   B CB  1 
ATOM   4885 C CG  . ARG   B 1 266 ? -66.40177  -19.66842 -88.94225  1.000 47.58944  ? 266 ARG   B CG  1 
ATOM   4886 C CD  . ARG   B 1 266 ? -66.49778  -20.96044 -89.80583  1.000 40.36439  ? 266 ARG   B CD  1 
ATOM   4887 N NE  . ARG   B 1 266 ? -67.73269  -21.70097 -89.51491  1.000 35.79523  ? 266 ARG   B NE  1 
ATOM   4888 C CZ  . ARG   B 1 266 ? -68.39959  -22.46179 -90.38768  1.000 48.24446  ? 266 ARG   B CZ  1 
ATOM   4889 N NH1 . ARG   B 1 266 ? -67.97201  -22.60475 -91.64790  1.000 34.60604  ? 266 ARG   B NH1 1 
ATOM   4890 N NH2 . ARG   B 1 266 ? -69.50962  -23.08576 -89.99482  1.000 37.45294  ? 266 ARG   B NH2 1 
ATOM   4891 N N   . GLN   B 1 267 ? -66.36721  -16.56421 -91.28758  1.000 21.06417  ? 267 GLN   B N   1 
ATOM   4892 C CA  . GLN   B 1 267 ? -67.45709  -16.02391 -92.08793  1.000 22.75533  ? 267 GLN   B CA  1 
ATOM   4893 C C   . GLN   B 1 267 ? -67.25334  -16.34693 -93.55390  1.000 22.03281  ? 267 GLN   B C   1 
ATOM   4894 O O   . GLN   B 1 267 ? -68.20259  -16.73343 -94.24809  1.000 18.58561  ? 267 GLN   B O   1 
ATOM   4895 C CB  . GLN   B 1 267 ? -67.58609  -14.52088 -91.90414  1.000 22.56889  ? 267 GLN   B CB  1 
ATOM   4896 C CG  . GLN   B 1 267 ? -68.76772  -13.97536 -92.67796  1.000 16.01930  ? 267 GLN   B CG  1 
ATOM   4897 C CD  . GLN   B 1 267 ? -68.93383  -12.49733 -92.49837  1.000 21.55903  ? 267 GLN   B CD  1 
ATOM   4898 O OE1 . GLN   B 1 267 ? -68.07423  -11.71866 -92.90435  1.000 22.34805  ? 267 GLN   B OE1 1 
ATOM   4899 N NE2 . GLN   B 1 267 ? -70.03844  -12.09248 -91.87549  1.000 17.08434  ? 267 GLN   B NE2 1 
ATOM   4900 N N   . ALA   B 1 268 ? -66.01012  -16.22716 -94.03137  1.000 20.62003  ? 268 ALA   B N   1 
ATOM   4901 C CA  . ALA   B 1 268 ? -65.71255  -16.51708 -95.43134  1.000 20.31673  ? 268 ALA   B CA  1 
ATOM   4902 C C   . ALA   B 1 268 ? -65.99329  -17.97750 -95.76066  1.000 19.19408  ? 268 ALA   B C   1 
ATOM   4903 O O   . ALA   B 1 268 ? -66.63852  -18.28733 -96.77237  1.000 20.69484  ? 268 ALA   B O   1 
ATOM   4904 C CB  . ALA   B 1 268 ? -64.26117  -16.15516 -95.74732  1.000 20.66333  ? 268 ALA   B CB  1 
ATOM   4905 N N   . GLU   B 1 269 ? -65.53955  -18.89228 -94.90635  1.000 19.20652  ? 269 GLU   B N   1 
ATOM   4906 C CA  . GLU   B 1 269 ? -65.83580  -20.30336 -95.13914  1.000 24.37913  ? 269 GLU   B CA  1 
ATOM   4907 C C   . GLU   B 1 269 ? -67.33574  -20.56042 -95.11725  1.000 22.66203  ? 269 GLU   B C   1 
ATOM   4908 O O   . GLU   B 1 269 ? -67.86413  -21.28794 -95.97290  1.000 22.92493  ? 269 GLU   B O   1 
ATOM   4909 C CB  . GLU   B 1 269 ? -65.13588  -21.17367 -94.09568  1.000 30.47145  ? 269 GLU   B CB  1 
ATOM   4910 C CG  . GLU   B 1 269 ? -65.37505  -22.66873 -94.28719  1.000 30.34285  ? 269 GLU   B CG  1 
ATOM   4911 C CD  . GLU   B 1 269 ? -64.82104  -23.50800 -93.14439  1.000 39.98829  ? 269 GLU   B CD  1 
ATOM   4912 O OE1 . GLU   B 1 269 ? -64.69780  -22.98648 -92.00815  1.000 48.44639  ? 269 GLU   B OE1 1 
ATOM   4913 O OE2 . GLU   B 1 269 ? -64.51708  -24.69796 -93.38423  1.000 57.25391  ? 269 GLU   B OE2 1 
ATOM   4914 N N   . ARG   B 1 270 ? -68.03657  -19.94959 -94.15652  1.000 15.55236  ? 270 ARG   B N   1 
ATOM   4915 C CA  . ARG   B 1 270 ? -69.48127  -20.12899 -94.02895  1.000 20.44134  ? 270 ARG   B CA  1 
ATOM   4916 C C   . ARG   B 1 270 ? -70.21566  -19.67167 -95.28587  1.000 21.62808  ? 270 ARG   B C   1 
ATOM   4917 O O   . ARG   B 1 270 ? -71.05896  -20.39811 -95.82555  1.000 20.01068  ? 270 ARG   B O   1 
ATOM   4918 C CB  . ARG   B 1 270 ? -69.98658  -19.36761 -92.80123  1.000 22.18975  ? 270 ARG   B CB  1 
ATOM   4919 C CG  . ARG   B 1 270 ? -71.48958  -19.34221 -92.63885  1.000 16.75512  ? 270 ARG   B CG  1 
ATOM   4920 C CD  . ARG   B 1 270 ? -72.02527  -20.68974 -92.22170  1.000 19.08027  ? 270 ARG   B CD  1 
ATOM   4921 N NE  . ARG   B 1 270 ? -73.20299  -20.50226 -91.39275  1.000 22.67144  ? 270 ARG   B NE  1 
ATOM   4922 C CZ  . ARG   B 1 270 ? -74.09920  -21.44103 -91.12178  1.000 23.30473  ? 270 ARG   B CZ  1 
ATOM   4923 N NH1 . ARG   B 1 270 ? -73.94630  -22.66254 -91.61579  1.000 14.94502  ? 270 ARG   B NH1 1 
ATOM   4924 N NH2 . ARG   B 1 270 ? -75.14727  -21.14936 -90.34961  1.000 17.85201  ? 270 ARG   B NH2 1 
ATOM   4925 N N   . TYR   B 1 271 ? -69.90636  -18.46670 -95.76741  1.000 14.87480  ? 271 TYR   B N   1 
ATOM   4926 C CA  . TYR   B 1 271 ? -70.55877  -17.96788 -96.97161  1.000 17.26901  ? 271 TYR   B CA  1 
ATOM   4927 C C   . TYR   B 1 271 ? -70.20433  -18.82223 -98.18276  1.000 23.90823  ? 271 TYR   B C   1 
ATOM   4928 O O   . TYR   B 1 271 ? -71.06048  -19.08802 -99.04075  1.000 25.00877  ? 271 TYR   B O   1 
ATOM   4929 C CB  . TYR   B 1 271 ? -70.17105  -16.51263 -97.21250  1.000 15.09647  ? 271 TYR   B CB  1 
ATOM   4930 C CG  . TYR   B 1 271 ? -71.16821  -15.49507 -96.70735  1.000 15.43382  ? 271 TYR   B CG  1 
ATOM   4931 C CD1 . TYR   B 1 271 ? -72.48454  -15.48749 -97.16039  1.000 16.21451  ? 271 TYR   B CD1 1 
ATOM   4932 C CD2 . TYR   B 1 271 ? -70.78500  -14.52170 -95.78614  1.000 15.44014  ? 271 TYR   B CD2 1 
ATOM   4933 C CE1 . TYR   B 1 271 ? -73.39555  -14.52496 -96.71118  1.000 15.34523  ? 271 TYR   B CE1 1 
ATOM   4934 C CE2 . TYR   B 1 271 ? -71.67300  -13.56610 -95.33698  1.000 13.73332  ? 271 TYR   B CE2 1 
ATOM   4935 C CZ  . TYR   B 1 271 ? -72.98163  -13.56979 -95.79925  1.000 16.67002  ? 271 TYR   B CZ  1 
ATOM   4936 O OH  . TYR   B 1 271 ? -73.86257  -12.61247 -95.33352  1.000 19.85251  ? 271 TYR   B OH  1 
ATOM   4937 N N   . GLY   B 1 272 ? -68.94891  -19.27291 -98.26694  1.000 21.11072  ? 272 GLY   B N   1 
ATOM   4938 C CA  . GLY   B 1 272 ? -68.58985  -20.19831 -99.32821  1.000 16.88953  ? 272 GLY   B CA  1 
ATOM   4939 C C   . GLY   B 1 272 ? -69.40804  -21.47086 -99.26854  1.000 19.04697  ? 272 GLY   B C   1 
ATOM   4940 O O   . GLY   B 1 272 ? -69.95778  -21.92188 -100.27756 1.000 19.33561  ? 272 GLY   B O   1 
ATOM   4941 N N   . GLN   B 1 273 ? -69.51883  -22.05832 -98.07332  1.000 21.37249  ? 273 GLN   B N   1 
ATOM   4942 C CA  . GLN   B 1 273 ? -70.30845  -23.27648 -97.93646  1.000 23.20482  ? 273 GLN   B CA  1 
ATOM   4943 C C   . GLN   B 1 273 ? -71.76407  -23.02877 -98.30046  1.000 27.27479  ? 273 GLN   B C   1 
ATOM   4944 O O   . GLN   B 1 273 ? -72.40899  -23.87316 -98.93550  1.000 27.68759  ? 273 GLN   B O   1 
ATOM   4945 C CB  . GLN   B 1 273 ? -70.19430  -23.81316 -96.51425  1.000 25.93628  ? 273 GLN   B CB  1 
ATOM   4946 C CG  . GLN   B 1 273 ? -68.82846  -24.39607 -96.18018  1.000 20.07197  ? 273 GLN   B CG  1 
ATOM   4947 C CD  . GLN   B 1 273 ? -68.66911  -24.64821 -94.68886  1.000 30.14101  ? 273 GLN   B CD  1 
ATOM   4948 O OE1 . GLN   B 1 273 ? -69.34120  -24.02212 -93.87054  1.000 37.26725  ? 273 GLN   B OE1 1 
ATOM   4949 N NE2 . GLN   B 1 273 ? -67.76641  -25.55014 -94.32839  1.000 28.87924  ? 273 GLN   B NE2 1 
ATOM   4950 N N   . ILE   B 1 274 ? -72.28663  -21.85787 -97.92858  1.000 28.38030  ? 274 ILE   B N   1 
ATOM   4951 C CA  . ILE   B 1 274 ? -73.70544  -21.56054 -98.10137  1.000 21.04380  ? 274 ILE   B CA  1 
ATOM   4952 C C   . ILE   B 1 274 ? -74.03880  -21.39876 -99.57433  1.000 22.78696  ? 274 ILE   B C   1 
ATOM   4953 O O   . ILE   B 1 274 ? -75.04369  -21.93071 -100.07127 1.000 20.00893  ? 274 ILE   B O   1 
ATOM   4954 C CB  . ILE   B 1 274 ? -74.06219  -20.29781 -97.29743  1.000 20.61506  ? 274 ILE   B CB  1 
ATOM   4955 C CG1 . ILE   B 1 274 ? -74.24032  -20.64187 -95.82106  1.000 18.41446  ? 274 ILE   B CG1 1 
ATOM   4956 C CG2 . ILE   B 1 274 ? -75.29044  -19.60549 -97.86784  1.000 13.66665  ? 274 ILE   B CG2 1 
ATOM   4957 C CD1 . ILE   B 1 274 ? -74.40580  -19.40091 -94.98103  1.000 25.67589  ? 274 ILE   B CD1 1 
ATOM   4958 N N   . PHE   B 1 275 ? -73.19147  -20.67895 -100.30452 1.000 24.56489  ? 275 PHE   B N   1 
ATOM   4959 C CA  . PHE   B 1 275 ? -73.48170  -20.47583 -101.71289 1.000 29.87825  ? 275 PHE   B CA  1 
ATOM   4960 C C   . PHE   B 1 275 ? -73.21170  -21.72740 -102.53618 1.000 28.15661  ? 275 PHE   B C   1 
ATOM   4961 O O   . PHE   B 1 275 ? -73.88501  -21.95477 -103.54816 1.000 26.91810  ? 275 PHE   B O   1 
ATOM   4962 C CB  . PHE   B 1 275 ? -72.71448  -19.26487 -102.21524 1.000 18.01098  ? 275 PHE   B CB  1 
ATOM   4963 C CG  . PHE   B 1 275 ? -73.47861  -18.00800 -102.01913 1.000 25.09186  ? 275 PHE   B CG  1 
ATOM   4964 C CD1 . PHE   B 1 275 ? -74.52008  -17.68410 -102.87963 1.000 21.46779  ? 275 PHE   B CD1 1 
ATOM   4965 C CD2 . PHE   B 1 275 ? -73.24622  -17.20519 -100.91529 1.000 21.85023  ? 275 PHE   B CD2 1 
ATOM   4966 C CE1 . PHE   B 1 275 ? -75.27676  -16.54516 -102.68151 1.000 23.07902  ? 275 PHE   B CE1 1 
ATOM   4967 C CE2 . PHE   B 1 275 ? -74.00095  -16.05705 -100.71316 1.000 19.49198  ? 275 PHE   B CE2 1 
ATOM   4968 C CZ  . PHE   B 1 275 ? -75.01997  -15.73004 -101.59451 1.000 21.02847  ? 275 PHE   B CZ  1 
ATOM   4969 N N   . ALA   B 1 276 ? -72.27784  -22.57000 -102.10067 1.000 24.40800  ? 276 ALA   B N   1 
ATOM   4970 C CA  . ALA   B 1 276 ? -72.09558  -23.85061 -102.77097 1.000 27.82974  ? 276 ALA   B CA  1 
ATOM   4971 C C   . ALA   B 1 276 ? -73.34720  -24.70024 -102.62077 1.000 22.55269  ? 276 ALA   B C   1 
ATOM   4972 O O   . ALA   B 1 276 ? -73.78672  -25.35332 -103.57905 1.000 28.38718  ? 276 ALA   B O   1 
ATOM   4973 C CB  . ALA   B 1 276 ? -70.85892  -24.57082 -102.21394 1.000 20.81880  ? 276 ALA   B CB  1 
ATOM   4974 N N   . LEU   B 1 277 ? -73.97776  -24.64862 -101.44323 1.000 20.35035  ? 277 LEU   B N   1 
ATOM   4975 C CA  . LEU   B 1 277 ? -75.19466  -25.43067 -101.24285 1.000 26.79417  ? 277 LEU   B CA  1 
ATOM   4976 C C   . LEU   B 1 277 ? -76.37415  -24.84266 -102.01393 1.000 32.13400  ? 277 LEU   B C   1 
ATOM   4977 O O   . LEU   B 1 277 ? -77.16770  -25.58895 -102.60228 1.000 30.06309  ? 277 LEU   B O   1 
ATOM   4978 C CB  . LEU   B 1 277 ? -75.50311  -25.55809 -99.75035  1.000 21.80630  ? 277 LEU   B CB  1 
ATOM   4979 C CG  . LEU   B 1 277 ? -76.73406  -26.42029 -99.45958  1.000 41.18222  ? 277 LEU   B CG  1 
ATOM   4980 C CD1 . LEU   B 1 277 ? -76.42334  -27.89143 -99.62733  1.000 32.03900  ? 277 LEU   B CD1 1 
ATOM   4981 C CD2 . LEU   B 1 277 ? -77.20840  -26.17495 -98.04330  1.000 34.08552  ? 277 LEU   B CD2 1 
ATOM   4982 N N   . PHE   B 1 278 ? -76.49237  -23.51265 -102.05041 1.000 30.20617  ? 278 PHE   B N   1 
ATOM   4983 C CA  . PHE   B 1 278 ? -77.53788  -22.89049 -102.86459 1.000 31.91183  ? 278 PHE   B CA  1 
ATOM   4984 C C   . PHE   B 1 278 ? -77.37846  -23.25685 -104.33404 1.000 27.06253  ? 278 PHE   B C   1 
ATOM   4985 O O   . PHE   B 1 278 ? -78.35751  -23.58143 -105.01200 1.000 28.42615  ? 278 PHE   B O   1 
ATOM   4986 C CB  . PHE   B 1 278 ? -77.51353  -21.36576 -102.71130 1.000 25.93305  ? 278 PHE   B CB  1 
ATOM   4987 C CG  . PHE   B 1 278 ? -77.93124  -20.87774 -101.35757 1.000 20.10714  ? 278 PHE   B CG  1 
ATOM   4988 C CD1 . PHE   B 1 278 ? -78.58716  -21.72073 -100.46842 1.000 20.68112  ? 278 PHE   B CD1 1 
ATOM   4989 C CD2 . PHE   B 1 278 ? -77.68036  -19.56645 -100.97876 1.000 20.57493  ? 278 PHE   B CD2 1 
ATOM   4990 C CE1 . PHE   B 1 278 ? -78.97807  -21.26715 -99.22453  1.000 20.92634  ? 278 PHE   B CE1 1 
ATOM   4991 C CE2 . PHE   B 1 278 ? -78.06581  -19.10280 -99.73959  1.000 19.90723  ? 278 PHE   B CE2 1 
ATOM   4992 C CZ  . PHE   B 1 278 ? -78.71337  -19.95450 -98.85549  1.000 21.29413  ? 278 PHE   B CZ  1 
ATOM   4993 N N   . LYS   B 1 279 ? -76.14722  -23.16838 -104.84813 1.000 30.58288  ? 279 LYS   B N   1 
ATOM   4994 C CA  . LYS   B 1 279 ? -75.87382  -23.53332 -106.23482 1.000 31.65296  ? 279 LYS   B CA  1 
ATOM   4995 C C   . LYS   B 1 279 ? -76.28100  -24.97005 -106.50198 1.000 27.27717  ? 279 LYS   B C   1 
ATOM   4996 O O   . LYS   B 1 279 ? -76.85576  -25.28372 -107.54806 1.000 29.55867  ? 279 LYS   B O   1 
ATOM   4997 C CB  . LYS   B 1 279 ? -74.38750  -23.33433 -106.54014 1.000 29.62711  ? 279 LYS   B CB  1 
ATOM   4998 C CG  . LYS   B 1 279 ? -74.02217  -23.36915 -108.01577 1.000 33.99856  ? 279 LYS   B CG  1 
ATOM   4999 C CD  . LYS   B 1 279 ? -72.55264  -23.03126 -108.20474 1.000 39.06502  ? 279 LYS   B CD  1 
ATOM   5000 C CE  . LYS   B 1 279 ? -72.20439  -22.73191 -109.65552 1.000 38.66816  ? 279 LYS   B CE  1 
ATOM   5001 N NZ  . LYS   B 1 279 ? -72.68963  -21.39098 -110.07030 1.000 36.06107  ? 279 LYS   B NZ  1 
ATOM   5002 N N   . GLU   B 1 280 ? -76.00378  -25.84974 -105.54969 1.000 29.90381  ? 280 GLU   B N   1 
ATOM   5003 C CA  . GLU   B 1 280 ? -76.43341  -27.23086 -105.65705 1.000 26.60193  ? 280 GLU   B CA  1 
ATOM   5004 C C   . GLU   B 1 280 ? -77.93842  -27.33276 -105.86152 1.000 31.40835  ? 280 GLU   B C   1 
ATOM   5005 O O   . GLU   B 1 280 ? -78.40811  -28.21597 -106.58564 1.000 37.04140  ? 280 GLU   B O   1 
ATOM   5006 C CB  . GLU   B 1 280 ? -75.98517  -27.96972 -104.39902 1.000 32.82274  ? 280 GLU   B CB  1 
ATOM   5007 C CG  . GLU   B 1 280 ? -76.07589  -29.46936 -104.44270 1.000 27.85156  ? 280 GLU   B CG  1 
ATOM   5008 C CD  . GLU   B 1 280 ? -75.41663  -30.08342 -103.23122 1.000 30.31772  ? 280 GLU   B CD  1 
ATOM   5009 O OE1 . GLU   B 1 280 ? -74.63541  -29.37581 -102.55357 1.000 38.34193  ? 280 GLU   B OE1 1 
ATOM   5010 O OE2 . GLU   B 1 280 ? -75.68354  -31.26553 -102.94353 1.000 39.67419  ? 280 GLU   B OE2 1 
ATOM   5011 N N   . TYR   B 1 281 ? -78.71056  -26.42192 -105.27272 1.000 33.12200  ? 281 TYR   B N   1 
ATOM   5012 C CA  . TYR   B 1 281 ? -80.16495  -26.47105 -105.35901 1.000 30.21895  ? 281 TYR   B CA  1 
ATOM   5013 C C   . TYR   B 1 281 ? -80.73493  -25.37627 -106.26101 1.000 33.17627  ? 281 TYR   B C   1 
ATOM   5014 O O   . TYR   B 1 281 ? -81.87168  -24.92962 -106.06370 1.000 28.88916  ? 281 TYR   B O   1 
ATOM   5015 C CB  . TYR   B 1 281 ? -80.77185  -26.41607 -103.95676 1.000 31.02010  ? 281 TYR   B CB  1 
ATOM   5016 C CG  . TYR   B 1 281 ? -80.55404  -27.70595 -103.20510 1.000 28.76102  ? 281 TYR   B CG  1 
ATOM   5017 C CD1 . TYR   B 1 281 ? -81.44214  -28.76780 -103.34024 1.000 33.42759  ? 281 TYR   B CD1 1 
ATOM   5018 C CD2 . TYR   B 1 281 ? -79.44168  -27.88188 -102.39382 1.000 30.37865  ? 281 TYR   B CD2 1 
ATOM   5019 C CE1 . TYR   B 1 281 ? -81.24449  -29.96560 -102.65842 1.000 34.25895  ? 281 TYR   B CE1 1 
ATOM   5020 C CE2 . TYR   B 1 281 ? -79.22855  -29.07335 -101.71635 1.000 33.42934  ? 281 TYR   B CE2 1 
ATOM   5021 C CZ  . TYR   B 1 281 ? -80.13542  -30.11257 -101.85400 1.000 41.52492  ? 281 TYR   B CZ  1 
ATOM   5022 O OH  . TYR   B 1 281 ? -79.93453  -31.29892 -101.18723 1.000 37.34499  ? 281 TYR   B OH  1 
ATOM   5023 N N   . ARG   B 1 282 ? -79.96700  -24.97952 -107.28690 1.000 29.27507  ? 282 ARG   B N   1 
ATOM   5024 C CA  . ARG   B 1 282 ? -80.39045  -23.94567 -108.22958 1.000 29.78269  ? 282 ARG   B CA  1 
ATOM   5025 C C   . ARG   B 1 282 ? -81.73569  -24.24092 -108.89607 1.000 35.88261  ? 282 ARG   B C   1 
ATOM   5026 O O   . ARG   B 1 282 ? -82.41818  -23.30231 -109.32694 1.000 29.62823  ? 282 ARG   B O   1 
ATOM   5027 C CB  . ARG   B 1 282 ? -79.31279  -23.76051 -109.29798 1.000 36.73800  ? 282 ARG   B CB  1 
ATOM   5028 C CG  . ARG   B 1 282 ? -78.85965  -25.05949 -109.97141 1.000 35.84957  ? 282 ARG   B CG  1 
ATOM   5029 C CD  . ARG   B 1 282 ? -77.60626  -24.83901 -110.84107 1.000 28.02001  ? 282 ARG   B CD  1 
ATOM   5030 N NE  . ARG   B 1 282 ? -77.89835  -24.04989 -112.03575 1.000 39.21718  ? 282 ARG   B NE  1 
ATOM   5031 C CZ  . ARG   B 1 282 ? -78.55413  -24.50798 -113.10862 1.000 53.87937  ? 282 ARG   B CZ  1 
ATOM   5032 N NH1 . ARG   B 1 282 ? -78.99025  -25.76999 -113.15235 1.000 31.50433  ? 282 ARG   B NH1 1 
ATOM   5033 N NH2 . ARG   B 1 282 ? -78.77927  -23.70013 -114.14575 1.000 25.87594  ? 282 ARG   B NH2 1 
ATOM   5034 N N   . ASP   B 1 283 ? -82.13955  -25.51290 -108.98049 1.000 30.59126  ? 283 ASP   B N   1 
ATOM   5035 C CA  . ASP   B 1 283 ? -83.40147  -25.85120 -109.63267 1.000 36.83726  ? 283 ASP   B CA  1 
ATOM   5036 C C   . ASP   B 1 283 ? -84.61317  -25.43744 -108.80857 1.000 38.02253  ? 283 ASP   B C   1 
ATOM   5037 O O   . ASP   B 1 283 ? -85.68893  -25.21562 -109.37660 1.000 30.17024  ? 283 ASP   B O   1 
ATOM   5038 C CB  . ASP   B 1 283 ? -83.46934  -27.35186 -109.92290 1.000 36.06255  ? 283 ASP   B CB  1 
ATOM   5039 C CG  . ASP   B 1 283 ? -82.46579  -27.78066 -110.96333 1.000 48.90205  ? 283 ASP   B CG  1 
ATOM   5040 O OD1 . ASP   B 1 283 ? -82.12258  -26.94509 -111.82709 1.000 45.47291  ? 283 ASP   B OD1 1 
ATOM   5041 O OD2 . ASP   B 1 283 ? -82.00997  -28.94392 -110.90888 1.000 60.10697  ? 283 ASP   B OD2 1 
ATOM   5042 N N   . VAL   B 1 284 ? -84.48264  -25.36147 -107.48390 1.000 32.69913  ? 284 VAL   B N   1 
ATOM   5043 C CA  . VAL   B 1 284 ? -85.58853  -24.92476 -106.64257 1.000 28.61222  ? 284 VAL   B CA  1 
ATOM   5044 C C   . VAL   B 1 284 ? -85.38850  -23.51728 -106.09055 1.000 32.12549  ? 284 VAL   B C   1 
ATOM   5045 O O   . VAL   B 1 284 ? -86.38391  -22.84823 -105.76731 1.000 35.33245  ? 284 VAL   B O   1 
ATOM   5046 C CB  . VAL   B 1 284 ? -85.85528  -25.92044 -105.49571 1.000 36.03868  ? 284 VAL   B CB  1 
ATOM   5047 C CG1 . VAL   B 1 284 ? -86.42665  -27.23124 -106.05097 1.000 40.23324  ? 284 VAL   B CG1 1 
ATOM   5048 C CG2 . VAL   B 1 284 ? -84.59631  -26.19292 -104.72245 1.000 27.45775  ? 284 VAL   B CG2 1 
ATOM   5049 N N   . ILE   B 1 285 ? -84.15970  -23.02951 -106.00597 1.000 26.55797  ? 285 ILE   B N   1 
ATOM   5050 C CA  . ILE   B 1 285 ? -83.89885  -21.69139 -105.49320 1.000 26.04757  ? 285 ILE   B CA  1 
ATOM   5051 C C   . ILE   B 1 285 ? -83.85664  -20.72950 -106.66680 1.000 25.62993  ? 285 ILE   B C   1 
ATOM   5052 O O   . ILE   B 1 285 ? -83.01178  -20.86024 -107.55791 1.000 31.56762  ? 285 ILE   B O   1 
ATOM   5053 C CB  . ILE   B 1 285 ? -82.58611  -21.63836 -104.70139 1.000 24.73372  ? 285 ILE   B CB  1 
ATOM   5054 C CG1 . ILE   B 1 285 ? -82.68040  -22.51678 -103.45152 1.000 24.91865  ? 285 ILE   B CG1 1 
ATOM   5055 C CG2 . ILE   B 1 285 ? -82.22415  -20.17902 -104.37949 1.000 17.02987  ? 285 ILE   B CG2 1 
ATOM   5056 C CD1 . ILE   B 1 285 ? -81.44339  -22.45132 -102.57208 1.000 21.07695  ? 285 ILE   B CD1 1 
ATOM   5057 N N   . GLN   B 1 286 ? -84.74857  -19.74559 -106.66017 1.000 22.85369  ? 286 GLN   B N   1 
ATOM   5058 C CA  . GLN   B 1 286 ? -84.79337  -18.78495 -107.74873 1.000 26.82747  ? 286 GLN   B CA  1 
ATOM   5059 C C   . GLN   B 1 286 ? -84.21336  -17.42966 -107.38619 1.000 28.58277  ? 286 GLN   B C   1 
ATOM   5060 O O   . GLN   B 1 286 ? -83.89402  -16.65291 -108.29346 1.000 28.19127  ? 286 GLN   B O   1 
ATOM   5061 C CB  . GLN   B 1 286 ? -86.24177  -18.60907 -108.24993 1.000 25.54108  ? 286 GLN   B CB  1 
ATOM   5062 C CG  . GLN   B 1 286 ? -86.51618  -19.24377 -109.62843 1.000 50.65189  ? 286 GLN   B CG  1 
ATOM   5063 C CD  . GLN   B 1 286 ? -86.11702  -20.72756 -109.72915 1.000 54.30969  ? 286 GLN   B CD  1 
ATOM   5064 O OE1 . GLN   B 1 286 ? -86.87336  -21.61556 -109.31607 1.000 54.46785  ? 286 GLN   B OE1 1 
ATOM   5065 N NE2 . GLN   B 1 286 ? -84.92605  -20.99376 -110.28445 1.000 35.80985  ? 286 GLN   B NE2 1 
ATOM   5066 N N   . SER   B 1 287 ? -84.04478  -17.13019 -106.09888 1.000 27.30493  ? 287 SER   B N   1 
ATOM   5067 C CA  . SER   B 1 287 ? -83.58881  -15.79764 -105.72807 1.000 23.43013  ? 287 SER   B CA  1 
ATOM   5068 C C   . SER   B 1 287 ? -82.94420  -15.82840 -104.34732 1.000 17.02794  ? 287 SER   B C   1 
ATOM   5069 O O   . SER   B 1 287 ? -83.46129  -16.45675 -103.41661 1.000 18.78822  ? 287 SER   B O   1 
ATOM   5070 C CB  . SER   B 1 287 ? -84.74974  -14.79589 -105.76010 1.000 25.01778  ? 287 SER   B CB  1 
ATOM   5071 O OG  . SER   B 1 287 ? -84.28310  -13.49205 -105.50041 1.000 27.40114  ? 287 SER   B OG  1 
ATOM   5072 N N   . VAL   B 1 288 ? -81.81291  -15.14577 -104.23105 1.000 17.71418  ? 288 VAL   B N   1 
ATOM   5073 C CA  . VAL   B 1 288 ? -81.09330  -14.99341 -102.97680 1.000 18.68310  ? 288 VAL   B CA  1 
ATOM   5074 C C   . VAL   B 1 288 ? -80.93950  -13.50424 -102.72630 1.000 20.32882  ? 288 VAL   B C   1 
ATOM   5075 O O   . VAL   B 1 288 ? -80.21052  -12.81819 -103.45286 1.000 18.36079  ? 288 VAL   B O   1 
ATOM   5076 C CB  . VAL   B 1 288 ? -79.72701  -15.69621 -102.98972 1.000 17.92689  ? 288 VAL   B CB  1 
ATOM   5077 C CG1 . VAL   B 1 288 ? -79.14147  -15.66670 -101.61312 1.000 18.42853  ? 288 VAL   B CG1 1 
ATOM   5078 C CG2 . VAL   B 1 288 ? -79.86912  -17.15684 -103.41820 1.000 14.39098  ? 288 VAL   B CG2 1 
ATOM   5079 N N   . THR   B 1 289 ? -81.63197  -13.00069 -101.70737 1.000 18.67758  ? 289 THR   B N   1 
ATOM   5080 C CA  . THR   B 1 289 ? -81.56019  -11.60164 -101.31192 1.000 16.14086  ? 289 THR   B CA  1 
ATOM   5081 C C   . THR   B 1 289 ? -80.86890  -11.50532 -99.96488  1.000 19.19685  ? 289 THR   B C   1 
ATOM   5082 O O   . THR   B 1 289 ? -81.21100  -12.25969 -99.04361  1.000 17.59130  ? 289 THR   B O   1 
ATOM   5083 C CB  . THR   B 1 289 ? -82.96059  -10.99762 -101.22401 1.000 14.96854  ? 289 THR   B CB  1 
ATOM   5084 O OG1 . THR   B 1 289 ? -83.58750  -11.11763 -102.49475 1.000 17.06814  ? 289 THR   B OG1 1 
ATOM   5085 C CG2 . THR   B 1 289 ? -82.91241  -9.54096  -100.81753 1.000 11.20383  ? 289 THR   B CG2 1 
ATOM   5086 N N   . PHE   B 1 290 ? -79.89915  -10.58604 -99.86372  1.000 15.92422  ? 290 PHE   B N   1 
ATOM   5087 C CA  . PHE   B 1 290 ? -79.31004  -10.18282 -98.59015  1.000 15.74119  ? 290 PHE   B CA  1 
ATOM   5088 C C   . PHE   B 1 290 ? -80.17483  -9.12393  -97.92662  1.000 18.18530  ? 290 PHE   B C   1 
ATOM   5089 O O   . PHE   B 1 290 ? -80.82497  -8.32172  -98.60582  1.000 19.44105  ? 290 PHE   B O   1 
ATOM   5090 C CB  . PHE   B 1 290 ? -77.90916  -9.58775  -98.77485  1.000 17.38320  ? 290 PHE   B CB  1 
ATOM   5091 C CG  . PHE   B 1 290 ? -76.92582  -10.51175 -99.41582  1.000 19.27670  ? 290 PHE   B CG  1 
ATOM   5092 C CD1 . PHE   B 1 290 ? -76.80340  -10.56608 -100.80108 1.000 21.61136  ? 290 PHE   B CD1 1 
ATOM   5093 C CD2 . PHE   B 1 290 ? -76.09620  -11.31458 -98.63476  1.000 15.26190  ? 290 PHE   B CD2 1 
ATOM   5094 C CE1 . PHE   B 1 290 ? -75.87360  -11.42009 -101.40185 1.000 24.62437  ? 290 PHE   B CE1 1 
ATOM   5095 C CE2 . PHE   B 1 290 ? -75.15689  -12.16530 -99.23327  1.000 17.80053  ? 290 PHE   B CE2 1 
ATOM   5096 C CZ  . PHE   B 1 290 ? -75.05256  -12.21749 -100.61650 1.000 19.15275  ? 290 PHE   B CZ  1 
ATOM   5097 N N   . TRP   B 1 291 ? -80.15584  -9.09837  -96.58854  1.000 18.71426  ? 291 TRP   B N   1 
ATOM   5098 C CA  . TRP   B 1 291 ? -80.85433  -8.04150  -95.84542  1.000 12.26312  ? 291 TRP   B CA  1 
ATOM   5099 C C   . TRP   B 1 291 ? -79.94600  -6.82400  -95.67106  1.000 10.96792  ? 291 TRP   B C   1 
ATOM   5100 O O   . TRP   B 1 291 ? -79.62849  -6.37823  -94.56847  1.000 18.92705  ? 291 TRP   B O   1 
ATOM   5101 C CB  . TRP   B 1 291 ? -81.36814  -8.55790  -94.50671  1.000 11.86905  ? 291 TRP   B CB  1 
ATOM   5102 C CG  . TRP   B 1 291 ? -82.60643  -7.81583  -94.11995  1.000 14.98764  ? 291 TRP   B CG  1 
ATOM   5103 C CD1 . TRP   B 1 291 ? -82.77208  -6.98569  -93.04256  1.000 16.32021  ? 291 TRP   B CD1 1 
ATOM   5104 C CD2 . TRP   B 1 291 ? -83.84989  -7.80077  -94.83387  1.000 14.74320  ? 291 TRP   B CD2 1 
ATOM   5105 N NE1 . TRP   B 1 291 ? -84.04849  -6.46742  -93.03851  1.000 14.68467  ? 291 TRP   B NE1 1 
ATOM   5106 C CE2 . TRP   B 1 291 ? -84.72671  -6.94652  -94.13004  1.000 13.94362  ? 291 TRP   B CE2 1 
ATOM   5107 C CE3 . TRP   B 1 291 ? -84.30821  -8.42863  -96.00312  1.000 14.65653  ? 291 TRP   B CE3 1 
ATOM   5108 C CZ2 . TRP   B 1 291 ? -86.03295  -6.69697  -94.56164  1.000 14.76941  ? 291 TRP   B CZ2 1 
ATOM   5109 C CZ3 . TRP   B 1 291 ? -85.59849  -8.18039  -96.43219  1.000 15.99161  ? 291 TRP   B CZ3 1 
ATOM   5110 C CH2 . TRP   B 1 291 ? -86.45286  -7.32898  -95.70844  1.000 16.04788  ? 291 TRP   B CH2 1 
ATOM   5111 N N   . GLY   B 1 292 ? -79.55599  -6.27955  -96.80558  1.000 8.96988   ? 292 GLY   B N   1 
ATOM   5112 C CA  . GLY   B 1 292 ? -78.58591  -5.22518  -96.94461  1.000 11.79660  ? 292 GLY   B CA  1 
ATOM   5113 C C   . GLY   B 1 292 ? -77.68807  -5.56404  -98.10062  1.000 17.92312  ? 292 GLY   B C   1 
ATOM   5114 O O   . GLY   B 1 292 ? -78.00670  -6.44202  -98.90127  1.000 21.51719  ? 292 GLY   B O   1 
ATOM   5115 N N   . ILE   B 1 293 ? -76.53876  -4.89722  -98.18826  1.000 18.66510  ? 293 ILE   B N   1 
ATOM   5116 C CA  . ILE   B 1 293 ? -75.54659  -5.33775  -99.16232  1.000 16.72835  ? 293 ILE   B CA  1 
ATOM   5117 C C   . ILE   B 1 293 ? -74.13576  -5.15002  -98.61876  1.000 19.76876  ? 293 ILE   B C   1 
ATOM   5118 O O   . ILE   B 1 293 ? -73.22316  -5.91021  -98.96947  1.000 19.39191  ? 293 ILE   B O   1 
ATOM   5119 C CB  . ILE   B 1 293 ? -75.72617  -4.62561  -100.51908 1.000 16.06804  ? 293 ILE   B CB  1 
ATOM   5120 C CG1 . ILE   B 1 293 ? -74.79486  -5.25892  -101.55199 1.000 15.87126  ? 293 ILE   B CG1 1 
ATOM   5121 C CG2 . ILE   B 1 293 ? -75.54595  -3.08014  -100.40335 1.000 7.56737   ? 293 ILE   B CG2 1 
ATOM   5122 C CD1 . ILE   B 1 293 ? -74.99948  -4.74494  -102.95200 1.000 23.53676  ? 293 ILE   B CD1 1 
ATOM   5123 N N   . ALA   B 1 294 ? -73.93943  -4.14710  -97.76369  1.000 15.77035  ? 294 ALA   B N   1 
ATOM   5124 C CA  . ALA   B 1 294 ? -72.60877  -3.85197  -97.25164  1.000 17.82594  ? 294 ALA   B CA  1 
ATOM   5125 C C   . ALA   B 1 294 ? -72.69878  -3.55235  -95.76550  1.000 16.80574  ? 294 ALA   B C   1 
ATOM   5126 O O   . ALA   B 1 294 ? -73.76209  -3.21509  -95.24348  1.000 16.69511  ? 294 ALA   B O   1 
ATOM   5127 C CB  . ALA   B 1 294 ? -71.95354  -2.68591  -97.99359  1.000 14.78639  ? 294 ALA   B CB  1 
ATOM   5128 N N   . ASP   B 1 295 ? -71.55813  -3.67800  -95.08404  1.000 16.66777  ? 295 ASP   B N   1 
ATOM   5129 C CA  . ASP   B 1 295 ? -71.56408  -3.60852  -93.62865  1.000 15.78027  ? 295 ASP   B CA  1 
ATOM   5130 C C   . ASP   B 1 295 ? -71.71955  -2.18641  -93.09710  1.000 19.39344  ? 295 ASP   B C   1 
ATOM   5131 O O   . ASP   B 1 295 ? -71.75937  -2.01801  -91.87548  1.000 13.34694  ? 295 ASP   B O   1 
ATOM   5132 C CB  . ASP   B 1 295 ? -70.28871  -4.25449  -93.07012  1.000 16.84370  ? 295 ASP   B CB  1 
ATOM   5133 C CG  . ASP   B 1 295 ? -70.30205  -5.78931  -93.18542  1.000 25.91543  ? 295 ASP   B CG  1 
ATOM   5134 O OD1 . ASP   B 1 295 ? -71.36699  -6.35975  -93.55233  1.000 18.65402  ? 295 ASP   B OD1 1 
ATOM   5135 O OD2 . ASP   B 1 295 ? -69.24919  -6.42191  -92.91356  1.000 16.63822  ? 295 ASP   B OD2 1 
ATOM   5136 N N   . ASP   B 1 296 ? -71.80742  -1.15903  -93.94884  1.000 17.85169  ? 296 ASP   B N   1 
ATOM   5137 C CA  . ASP   B 1 296 ? -72.12223  0.15992   -93.40939  1.000 19.29314  ? 296 ASP   B CA  1 
ATOM   5138 C C   . ASP   B 1 296 ? -73.60392  0.33091   -93.07953  1.000 16.35824  ? 296 ASP   B C   1 
ATOM   5139 O O   . ASP   B 1 296 ? -73.96767  1.33260   -92.46461  1.000 16.52268  ? 296 ASP   B O   1 
ATOM   5140 C CB  . ASP   B 1 296 ? -71.66435  1.28636   -94.35083  1.000 18.46310  ? 296 ASP   B CB  1 
ATOM   5141 C CG  . ASP   B 1 296 ? -72.13251  1.10485   -95.78700  1.000 18.80744  ? 296 ASP   B CG  1 
ATOM   5142 O OD1 . ASP   B 1 296 ? -72.49338  -0.02023  -96.17996  1.000 19.76635  ? 296 ASP   B OD1 1 
ATOM   5143 O OD2 . ASP   B 1 296 ? -72.10223  2.10101   -96.53733  1.000 20.55374  ? 296 ASP   B OD2 1 
ATOM   5144 N N   . HIS   B 1 297 ? -74.46837  -0.61345  -93.43856  1.000 18.07282  ? 297 HIS   B N   1 
ATOM   5145 C CA  A HIS   B 1 297 ? -75.87479  -0.54205  -93.04070  0.736 16.58838  ? 297 HIS   B CA  1 
ATOM   5146 C CA  B HIS   B 1 297 ? -75.85967  -0.54183  -93.01120  0.264 16.53528  ? 297 HIS   B CA  1 
ATOM   5147 C C   . HIS   B 1 297 ? -76.40691  -1.95133  -92.85816  1.000 20.25454  ? 297 HIS   B C   1 
ATOM   5148 O O   . HIS   B 1 297 ? -76.53861  -2.68258  -93.84441  1.000 15.55607  ? 297 HIS   B O   1 
ATOM   5149 C CB  A HIS   B 1 297 ? -76.74864  0.17884   -94.05612  0.736 14.48186  ? 297 HIS   B CB  1 
ATOM   5150 C CB  B HIS   B 1 297 ? -76.69868  0.27474   -93.99764  0.264 14.63251  ? 297 HIS   B CB  1 
ATOM   5151 C CG  A HIS   B 1 297 ? -78.20737  0.05436   -93.72964  0.736 17.18644  ? 297 HIS   B CG  1 
ATOM   5152 C CG  B HIS   B 1 297 ? -77.25021  1.54264   -93.41430  0.264 19.47432  ? 297 HIS   B CG  1 
ATOM   5153 N ND1 A HIS   B 1 297 ? -78.87988  0.98793   -92.97109  0.736 15.37713  ? 297 HIS   B ND1 1 
ATOM   5154 N ND1 B HIS   B 1 297 ? -76.53521  2.72033   -93.37646  0.264 17.03175  ? 297 HIS   B ND1 1 
ATOM   5155 C CD2 A HIS   B 1 297 ? -79.09376  -0.94016  -93.97070  0.736 11.46878  ? 297 HIS   B CD2 1 
ATOM   5156 C CD2 B HIS   B 1 297 ? -78.44681  1.81455   -92.84168  0.264 17.85215  ? 297 HIS   B CD2 1 
ATOM   5157 C CE1 A HIS   B 1 297 ? -80.12562  0.59752   -92.79972  0.736 12.22282  ? 297 HIS   B CE1 1 
ATOM   5158 C CE1 B HIS   B 1 297 ? -77.27123  3.66636   -92.82300  0.264 14.09490  ? 297 HIS   B CE1 1 
ATOM   5159 N NE2 A HIS   B 1 297 ? -80.27899  -0.57285  -93.39030  0.736 15.57927  ? 297 HIS   B NE2 1 
ATOM   5160 N NE2 B HIS   B 1 297 ? -78.43161  3.14047   -92.48090  0.264 16.75167  ? 297 HIS   B NE2 1 
ATOM   5161 N N   . THR   B 1 298 ? -76.74975  -2.31146  -91.62395  1.000 15.84292  ? 298 THR   B N   1 
ATOM   5162 C CA  . THR   B 1 298 ? -77.33280  -3.61430  -91.34478  1.000 13.46355  ? 298 THR   B CA  1 
ATOM   5163 C C   . THR   B 1 298 ? -78.17009  -3.52001  -90.08195  1.000 16.73181  ? 298 THR   B C   1 
ATOM   5164 O O   . THR   B 1 298 ? -77.71790  -2.97649  -89.06774  1.000 16.35457  ? 298 THR   B O   1 
ATOM   5165 C CB  . THR   B 1 298 ? -76.26554  -4.70377  -91.17161  1.000 13.81689  ? 298 THR   B CB  1 
ATOM   5166 O OG1 . THR   B 1 298 ? -76.87813  -5.86981  -90.62246  1.000 13.22546  ? 298 THR   B OG1 1 
ATOM   5167 C CG2 . THR   B 1 298 ? -75.14340  -4.25197  -90.23284  1.000 12.09320  ? 298 THR   B CG2 1 
ATOM   5168 N N   . TRP   B 1 299 ? -79.37802  -4.07499  -90.13847  1.000 13.86150  ? 299 TRP   B N   1 
ATOM   5169 C CA  . TRP   B 1 299 ? -80.22611  -4.07236  -88.95562  1.000 17.05904  ? 299 TRP   B CA  1 
ATOM   5170 C C   . TRP   B 1 299 ? -79.60770  -4.84888  -87.80181  1.000 19.17839  ? 299 TRP   B C   1 
ATOM   5171 O O   . TRP   B 1 299 ? -80.07000  -4.69855  -86.66218  1.000 16.69692  ? 299 TRP   B O   1 
ATOM   5172 C CB  . TRP   B 1 299 ? -81.60754  -4.64825  -89.28728  1.000 12.92142  ? 299 TRP   B CB  1 
ATOM   5173 C CG  . TRP   B 1 299 ? -81.59359  -6.15009  -89.43096  1.000 12.84171  ? 299 TRP   B CG  1 
ATOM   5174 C CD1 . TRP   B 1 299 ? -80.77143  -6.89094  -90.23467  1.000 11.69687  ? 299 TRP   B CD1 1 
ATOM   5175 C CD2 . TRP   B 1 299 ? -82.43720  -7.08597  -88.75076  1.000 15.97728  ? 299 TRP   B CD2 1 
ATOM   5176 N NE1 . TRP   B 1 299 ? -81.05312  -8.22409  -90.09950  1.000 12.98004  ? 299 TRP   B NE1 1 
ATOM   5177 C CE2 . TRP   B 1 299 ? -82.06958  -8.37512  -89.19272  1.000 15.08363  ? 299 TRP   B CE2 1 
ATOM   5178 C CE3 . TRP   B 1 299 ? -83.47346  -6.95988  -87.81639  1.000 16.17975  ? 299 TRP   B CE3 1 
ATOM   5179 C CZ2 . TRP   B 1 299 ? -82.69913  -9.53347  -88.72751  1.000 16.61794  ? 299 TRP   B CZ2 1 
ATOM   5180 C CZ3 . TRP   B 1 299 ? -84.09990  -8.10565  -87.35918  1.000 17.58263  ? 299 TRP   B CZ3 1 
ATOM   5181 C CH2 . TRP   B 1 299 ? -83.70677  -9.37976  -87.80984  1.000 21.13896  ? 299 TRP   B CH2 1 
ATOM   5182 N N   . LEU   B 1 300 ? -78.58081  -5.66873  -88.05952  1.000 14.18980  ? 300 LEU   B N   1 
ATOM   5183 C CA  . LEU   B 1 300 ? -77.93053  -6.37033  -86.96170  1.000 15.20558  ? 300 LEU   B CA  1 
ATOM   5184 C C   . LEU   B 1 300 ? -77.07375  -5.44619  -86.10791  1.000 16.35597  ? 300 LEU   B C   1 
ATOM   5185 O O   . LEU   B 1 300 ? -76.66015  -5.84597  -85.01755  1.000 19.37283  ? 300 LEU   B O   1 
ATOM   5186 C CB  . LEU   B 1 300 ? -77.08309  -7.51373  -87.49455  1.000 15.88783  ? 300 LEU   B CB  1 
ATOM   5187 C CG  . LEU   B 1 300 ? -77.86068  -8.60378  -88.22300  1.000 20.86634  ? 300 LEU   B CG  1 
ATOM   5188 C CD1 . LEU   B 1 300 ? -76.89437  -9.73509  -88.61680  1.000 19.30931  ? 300 LEU   B CD1 1 
ATOM   5189 C CD2 . LEU   B 1 300 ? -79.03906  -9.11766  -87.37127  1.000 12.14132  ? 300 LEU   B CD2 1 
ATOM   5190 N N   . ASP   B 1 301 ? -76.80769  -4.22618  -86.57374  1.000 16.89201  ? 301 ASP   B N   1 
ATOM   5191 C CA  . ASP   B 1 301 ? -76.13696  -3.23193  -85.75226  1.000 17.33385  ? 301 ASP   B CA  1 
ATOM   5192 C C   . ASP   B 1 301 ? -76.94882  -2.86716  -84.51385  1.000 26.03213  ? 301 ASP   B C   1 
ATOM   5193 O O   . ASP   B 1 301 ? -76.38984  -2.31127  -83.55657  1.000 22.81628  ? 301 ASP   B O   1 
ATOM   5194 C CB  . ASP   B 1 301 ? -75.86700  -1.97048  -86.57725  1.000 16.73297  ? 301 ASP   B CB  1 
ATOM   5195 C CG  . ASP   B 1 301 ? -74.61895  -2.08605  -87.44710  1.000 24.18816  ? 301 ASP   B CG  1 
ATOM   5196 O OD1 . ASP   B 1 301 ? -73.87001  -3.08863  -87.29345  1.000 16.93607  ? 301 ASP   B OD1 1 
ATOM   5197 O OD2 . ASP   B 1 301 ? -74.38984  -1.16054  -88.27545  1.000 19.00378  ? 301 ASP   B OD2 1 
ATOM   5198 N N   . ASN   B 1 302 ? -78.25257  -3.16974  -84.50393  1.000 22.68214  ? 302 ASN   B N   1 
ATOM   5199 C CA  . ASN   B 1 302 ? -79.09729  -2.82857  -83.37252  1.000 20.83460  ? 302 ASN   B CA  1 
ATOM   5200 C C   . ASN   B 1 302 ? -79.94670  -3.97800  -82.87620  1.000 22.67434  ? 302 ASN   B C   1 
ATOM   5201 O O   . ASN   B 1 302 ? -80.75495  -3.77780  -81.96634  1.000 20.70860  ? 302 ASN   B O   1 
ATOM   5202 C CB  . ASN   B 1 302 ? -80.00985  -1.65285  -83.71721  1.000 20.66462  ? 302 ASN   B CB  1 
ATOM   5203 C CG  . ASN   B 1 302 ? -79.24005  -0.37066  -83.91096  1.000 23.93063  ? 302 ASN   B CG  1 
ATOM   5204 O OD1 . ASN   B 1 302 ? -78.61786  0.14345   -82.97676  1.000 21.08885  ? 302 ASN   B OD1 1 
ATOM   5205 N ND2 . ASN   B 1 302 ? -79.28065  0.15893   -85.12236  1.000 25.57534  ? 302 ASN   B ND2 1 
ATOM   5206 N N   . PHE   B 1 303 ? -79.79096  -5.16746  -83.43813  1.000 19.57348  ? 303 PHE   B N   1 
ATOM   5207 C CA  . PHE   B 1 303 ? -80.57804  -6.27760  -83.02993  1.000 16.79398  ? 303 PHE   B CA  1 
ATOM   5208 C C   . PHE   B 1 303 ? -79.64804  -7.48159  -83.07489  1.000 16.98145  ? 303 PHE   B C   1 
ATOM   5209 O O   . PHE   B 1 303 ? -78.93206  -7.66408  -84.06787  1.000 17.65720  ? 303 PHE   B O   1 
ATOM   5210 C CB  . PHE   B 1 303 ? -81.80282  -6.49571  -83.93864  1.000 12.12769  ? 303 PHE   B CB  1 
ATOM   5211 C CG  . PHE   B 1 303 ? -82.48992  -7.80873  -83.70035  1.000 17.20121  ? 303 PHE   B CG  1 
ATOM   5212 C CD1 . PHE   B 1 303 ? -83.31172  -7.98656  -82.59417  1.000 18.45068  ? 303 PHE   B CD1 1 
ATOM   5213 C CD2 . PHE   B 1 303 ? -82.28607  -8.88221  -84.55635  1.000 17.75232  ? 303 PHE   B CD2 1 
ATOM   5214 C CE1 . PHE   B 1 303 ? -83.92885  -9.21018  -82.35426  1.000 14.39434  ? 303 PHE   B CE1 1 
ATOM   5215 C CE2 . PHE   B 1 303 ? -82.91010  -10.10890 -84.32218  1.000 18.43134  ? 303 PHE   B CE2 1 
ATOM   5216 C CZ  . PHE   B 1 303 ? -83.72775  -10.26578 -83.22165  1.000 18.54810  ? 303 PHE   B CZ  1 
ATOM   5217 N N   . PRO   B 1 304 ? -79.63553  -8.32317  -82.04222  1.000 22.52689  ? 304 PRO   B N   1 
ATOM   5218 C CA  . PRO   B 1 304 ? -80.42222  -8.19759  -80.81528  1.000 18.17396  ? 304 PRO   B CA  1 
ATOM   5219 C C   . PRO   B 1 304 ? -79.83268  -7.28642  -79.74731  1.000 21.47857  ? 304 PRO   B C   1 
ATOM   5220 O O   . PRO   B 1 304 ? -80.36551  -7.25586  -78.64872  1.000 28.08572  ? 304 PRO   B O   1 
ATOM   5221 C CB  . PRO   B 1 304 ? -80.47883  -9.62668  -80.29262  1.000 16.72709  ? 304 PRO   B CB  1 
ATOM   5222 C CG  . PRO   B 1 304 ? -79.29165  -10.27606 -80.84807  1.000 19.48981  ? 304 PRO   B CG  1 
ATOM   5223 C CD  . PRO   B 1 304 ? -79.00555  -9.64310  -82.16382  1.000 18.86154  ? 304 PRO   B CD  1 
ATOM   5224 N N   . VAL   B 1 305 ? -78.76042  -6.55970  -80.03348  1.000 22.12670  ? 305 VAL   B N   1 
ATOM   5225 C CA  . VAL   B 1 305 ? -78.16880  -5.63150  -79.07113  1.000 19.33718  ? 305 VAL   B CA  1 
ATOM   5226 C C   . VAL   B 1 305 ? -78.10359  -4.24771  -79.69094  1.000 22.49946  ? 305 VAL   B C   1 
ATOM   5227 O O   . VAL   B 1 305 ? -77.60179  -4.08252  -80.81042  1.000 28.33765  ? 305 VAL   B O   1 
ATOM   5228 C CB  . VAL   B 1 305 ? -76.77217  -6.08277  -78.61354  1.000 21.52293  ? 305 VAL   B CB  1 
ATOM   5229 C CG1 . VAL   B 1 305 ? -76.32724  -5.24872  -77.42343  1.000 21.91905  ? 305 VAL   B CG1 1 
ATOM   5230 C CG2 . VAL   B 1 305 ? -76.81246  -7.54818  -78.22831  1.000 16.12205  ? 305 VAL   B CG2 1 
ATOM   5231 N N   . HIS   B 1 306 ? -78.61360  -3.26133  -78.96535  1.000 21.55245  ? 306 HIS   B N   1 
ATOM   5232 C CA  . HIS   B 1 306 ? -78.66364  -1.90222  -79.47719  1.000 21.61933  ? 306 HIS   B CA  1 
ATOM   5233 C C   . HIS   B 1 306 ? -77.26647  -1.30272  -79.50254  1.000 24.56723  ? 306 HIS   B C   1 
ATOM   5234 O O   . HIS   B 1 306 ? -76.51301  -1.42045  -78.53472  1.000 23.25463  ? 306 HIS   B O   1 
ATOM   5235 C CB  . HIS   B 1 306 ? -79.58898  -1.04409  -78.61641  1.000 22.11449  ? 306 HIS   B CB  1 
ATOM   5236 C CG  . HIS   B 1 306 ? -79.88119  0.29754   -79.21256  1.000 32.29861  ? 306 HIS   B CG  1 
ATOM   5237 N ND1 . HIS   B 1 306 ? -80.66634  0.45779   -80.33806  1.000 29.62135  ? 306 HIS   B ND1 1 
ATOM   5238 C CD2 . HIS   B 1 306 ? -79.47791  1.53875   -78.85348  1.000 24.38029  ? 306 HIS   B CD2 1 
ATOM   5239 C CE1 . HIS   B 1 306 ? -80.73986  1.74155   -80.64012  1.000 35.84104  ? 306 HIS   B CE1 1 
ATOM   5240 N NE2 . HIS   B 1 306 ? -80.02806  2.41835   -79.75427  1.000 35.66675  ? 306 HIS   B NE2 1 
ATOM   5241 N N   . GLY   B 1 307 ? -76.91501  -0.67209  -80.61778  1.000 30.20145  ? 307 GLY   B N   1 
ATOM   5242 C CA  . GLY   B 1 307 ? -75.62487  -0.01790  -80.71344  1.000 23.98546  ? 307 GLY   B CA  1 
ATOM   5243 C C   . GLY   B 1 307 ? -74.41092  -0.92232  -80.70926  1.000 22.57453  ? 307 GLY   B C   1 
ATOM   5244 O O   . GLY   B 1 307 ? -73.32225  -0.46496  -80.36070  1.000 31.13802  ? 307 GLY   B O   1 
ATOM   5245 N N   . ARG   B 1 308 ? -74.55309  -2.19132  -81.07860  1.000 21.65102  ? 308 ARG   B N   1 
ATOM   5246 C CA  . ARG   B 1 308 ? -73.41463  -3.09694  -81.20126  1.000 25.14798  ? 308 ARG   B CA  1 
ATOM   5247 C C   . ARG   B 1 308 ? -73.15751  -3.37601  -82.67844  1.000 29.12225  ? 308 ARG   B C   1 
ATOM   5248 O O   . ARG   B 1 308 ? -73.98051  -4.01154  -83.34429  1.000 25.39350  ? 308 ARG   B O   1 
ATOM   5249 C CB  . ARG   B 1 308 ? -73.64916  -4.41176  -80.46864  1.000 18.93078  ? 308 ARG   B CB  1 
ATOM   5250 C CG  . ARG   B 1 308 ? -72.67202  -5.45859  -80.97762  1.000 29.21788  ? 308 ARG   B CG  1 
ATOM   5251 C CD  . ARG   B 1 308 ? -72.91483  -6.81202  -80.41986  1.000 21.67151  ? 308 ARG   B CD  1 
ATOM   5252 N NE  . ARG   B 1 308 ? -73.99488  -7.51058  -81.09749  1.000 21.19389  ? 308 ARG   B NE  1 
ATOM   5253 C CZ  . ARG   B 1 308 ? -74.40564  -8.71515  -80.72580  1.000 24.80674  ? 308 ARG   B CZ  1 
ATOM   5254 N NH1 . ARG   B 1 308 ? -73.80489  -9.31206  -79.68976  1.000 17.24081  ? 308 ARG   B NH1 1 
ATOM   5255 N NH2 . ARG   B 1 308 ? -75.40796  -9.31516  -81.37150  1.000 20.97341  ? 308 ARG   B NH2 1 
ATOM   5256 N N   . LYS   B 1 309 ? -72.00306  -2.94327  -83.17625  1.000 24.08219  ? 309 LYS   B N   1 
ATOM   5257 C CA  . LYS   B 1 309 ? -71.69188  -3.12434  -84.58871  1.000 21.08073  ? 309 LYS   B CA  1 
ATOM   5258 C C   . LYS   B 1 309 ? -71.56599  -4.60711  -84.94193  1.000 17.63824  ? 309 LYS   B C   1 
ATOM   5259 O O   . LYS   B 1 309 ? -71.00936  -5.41379  -84.18917  1.000 18.58762  ? 309 LYS   B O   1 
ATOM   5260 C CB  . LYS   B 1 309 ? -70.40070  -2.37329  -84.94013  1.000 14.96239  ? 309 LYS   B CB  1 
ATOM   5261 C CG  . LYS   B 1 309 ? -70.09982  -2.25347  -86.44365  1.000 15.82502  ? 309 LYS   B CG  1 
ATOM   5262 C CD  . LYS   B 1 309 ? -70.98351  -1.18055  -87.09915  1.000 17.12537  ? 309 LYS   B CD  1 
ATOM   5263 C CE  . LYS   B 1 309 ? -70.98651  -1.29713  -88.62967  1.000 13.29276  ? 309 LYS   B CE  1 
ATOM   5264 N NZ  . LYS   B 1 309 ? -71.78736  -2.48349  -89.07989  1.000 14.20613  ? 309 LYS   B NZ  1 
ATOM   5265 N N   . ASN   B 1 310 ? -72.10405  -4.96920  -86.09494  1.000 15.39501  ? 310 ASN   B N   1 
ATOM   5266 C CA  . ASN   B 1 310 ? -71.96880  -6.31202  -86.62856  1.000 14.65288  ? 310 ASN   B CA  1 
ATOM   5267 C C   . ASN   B 1 310 ? -71.40250  -6.16997  -88.03708  1.000 12.91798  ? 310 ASN   B C   1 
ATOM   5268 O O   . ASN   B 1 310 ? -71.38297  -5.06991  -88.59744  1.000 13.77659  ? 310 ASN   B O   1 
ATOM   5269 C CB  . ASN   B 1 310 ? -73.31868  -7.05296  -86.58660  1.000 14.15939  ? 310 ASN   B CB  1 
ATOM   5270 C CG  . ASN   B 1 310 ? -73.15781  -8.55734  -86.55084  1.000 17.69833  ? 310 ASN   B CG  1 
ATOM   5271 O OD1 . ASN   B 1 310 ? -72.17024  -9.08914  -87.05907  1.000 17.88888  ? 310 ASN   B OD1 1 
ATOM   5272 N ND2 . ASN   B 1 310 ? -74.13323  -9.25809  -85.96681  1.000 12.27633  ? 310 ASN   B ND2 1 
ATOM   5273 N N   . TRP   B 1 311 ? -70.88148  -7.26402  -88.59265  1.000 12.41234  ? 311 TRP   B N   1 
ATOM   5274 C CA  . TRP   B 1 311 ? -70.27040  -7.24674  -89.93221  1.000 18.65458  ? 311 TRP   B CA  1 
ATOM   5275 C C   . TRP   B 1 311 ? -70.74211  -8.45566  -90.72851  1.000 17.08909  ? 311 TRP   B C   1 
ATOM   5276 O O   . TRP   B 1 311 ? -69.98214  -9.39615  -90.98794  1.000 19.21524  ? 311 TRP   B O   1 
ATOM   5277 C CB  . TRP   B 1 311 ? -68.74217  -7.20131  -89.83433  1.000 15.89816  ? 311 TRP   B CB  1 
ATOM   5278 C CG  . TRP   B 1 311 ? -68.27165  -6.14860  -88.88955  1.000 13.89114  ? 311 TRP   B CG  1 
ATOM   5279 C CD1 . TRP   B 1 311 ? -67.96299  -4.85726  -89.19303  1.000 15.83878  ? 311 TRP   B CD1 1 
ATOM   5280 C CD2 . TRP   B 1 311 ? -68.09788  -6.28176  -87.47664  1.000 15.03142  ? 311 TRP   B CD2 1 
ATOM   5281 N NE1 . TRP   B 1 311 ? -67.57738  -4.18326  -88.06103  1.000 15.89147  ? 311 TRP   B NE1 1 
ATOM   5282 C CE2 . TRP   B 1 311 ? -67.66169  -5.03448  -86.99031  1.000 19.52425  ? 311 TRP   B CE2 1 
ATOM   5283 C CE3 . TRP   B 1 311 ? -68.23817  -7.34477  -86.57729  1.000 16.96320  ? 311 TRP   B CE3 1 
ATOM   5284 C CZ2 . TRP   B 1 311 ? -67.37884  -4.81467  -85.63667  1.000 18.17525  ? 311 TRP   B CZ2 1 
ATOM   5285 C CZ3 . TRP   B 1 311 ? -67.94900  -7.12760  -85.24276  1.000 15.18600  ? 311 TRP   B CZ3 1 
ATOM   5286 C CH2 . TRP   B 1 311 ? -67.52407  -5.87172  -84.78399  1.000 14.06889  ? 311 TRP   B CH2 1 
ATOM   5287 N N   . PRO   B 1 312 ? -72.00684  -8.45500  -91.15129  1.000 16.69731  ? 312 PRO   B N   1 
ATOM   5288 C CA  . PRO   B 1 312 ? -72.65895  -9.69235  -91.61133  1.000 13.66061  ? 312 PRO   B CA  1 
ATOM   5289 C C   . PRO   B 1 312 ? -72.70092  -9.92908  -93.11726  1.000 16.81112  ? 312 PRO   B C   1 
ATOM   5290 O O   . PRO   B 1 312 ? -73.20177  -10.98444 -93.52700  1.000 15.43859  ? 312 PRO   B O   1 
ATOM   5291 C CB  . PRO   B 1 312 ? -74.09304  -9.51096  -91.08085  1.000 21.18995  ? 312 PRO   B CB  1 
ATOM   5292 C CG  . PRO   B 1 312 ? -74.15777  -8.10026  -90.45915  1.000 14.47560  ? 312 PRO   B CG  1 
ATOM   5293 C CD  . PRO   B 1 312 ? -72.97540  -7.36684  -90.95414  1.000 13.43624  ? 312 PRO   B CD  1 
ATOM   5294 N N   . LEU   B 1 313 ? -72.22197  -9.00051  -93.93674  1.000 16.63863  ? 313 LEU   B N   1 
ATOM   5295 C CA  . LEU   B 1 313 ? -72.46177  -9.01785  -95.37570  1.000 20.61553  ? 313 LEU   B CA  1 
ATOM   5296 C C   . LEU   B 1 313 ? -71.16462  -9.25776  -96.15628  1.000 18.68522  ? 313 LEU   B C   1 
ATOM   5297 O O   . LEU   B 1 313 ? -70.08102  -9.41013  -95.58770  1.000 14.34278  ? 313 LEU   B O   1 
ATOM   5298 C CB  . LEU   B 1 313 ? -73.14792  -7.71378  -95.79380  1.000 14.46914  ? 313 LEU   B CB  1 
ATOM   5299 C CG  . LEU   B 1 313 ? -74.50439  -7.60391  -95.07980  1.000 22.51497  ? 313 LEU   B CG  1 
ATOM   5300 C CD1 . LEU   B 1 313 ? -75.04919  -6.17051  -94.98296  1.000 12.87916  ? 313 LEU   B CD1 1 
ATOM   5301 C CD2 . LEU   B 1 313 ? -75.52315  -8.55931  -95.74517  1.000 18.96994  ? 313 LEU   B CD2 1 
ATOM   5302 N N   . LEU   B 1 314 ? -71.29556  -9.30063  -97.48973  1.000 20.23068  ? 314 LEU   B N   1 
ATOM   5303 C CA  . LEU   B 1 314 ? -70.16993  -9.61037  -98.36677  1.000 16.45899  ? 314 LEU   B CA  1 
ATOM   5304 C C   . LEU   B 1 314 ? -69.22454  -8.43081  -98.55623  1.000 17.84540  ? 314 LEU   B C   1 
ATOM   5305 O O   . LEU   B 1 314 ? -68.04867  -8.63698  -98.87675  1.000 22.53193  ? 314 LEU   B O   1 
ATOM   5306 C CB  . LEU   B 1 314 ? -70.67442  -10.08604 -99.73279  1.000 16.33367  ? 314 LEU   B CB  1 
ATOM   5307 C CG  . LEU   B 1 314 ? -71.45454  -11.40227 -99.79750  1.000 19.08709  ? 314 LEU   B CG  1 
ATOM   5308 C CD1 . LEU   B 1 314 ? -71.60380  -11.86727 -101.24837 1.000 15.90247  ? 314 LEU   B CD1 1 
ATOM   5309 C CD2 . LEU   B 1 314 ? -70.80391  -12.50006 -98.93774  1.000 11.12552  ? 314 LEU   B CD2 1 
ATOM   5310 N N   . PHE   B 1 315 ? -69.69395  -7.20986  -98.34703  1.000 16.51720  ? 315 PHE   B N   1 
ATOM   5311 C CA  . PHE   B 1 315 ? -68.88388  -6.01903  -98.53639  1.000 14.24588  ? 315 PHE   B CA  1 
ATOM   5312 C C   . PHE   B 1 315 ? -68.71104  -5.29598  -97.20873  1.000 19.66973  ? 315 PHE   B C   1 
ATOM   5313 O O   . PHE   B 1 315 ? -69.60554  -5.30399  -96.35150  1.000 18.47009  ? 315 PHE   B O   1 
ATOM   5314 C CB  . PHE   B 1 315 ? -69.52478  -5.09897  -99.57784  1.000 16.90582  ? 315 PHE   B CB  1 
ATOM   5315 C CG  . PHE   B 1 315 ? -69.71480  -5.74904  -100.92376 1.000 12.36639  ? 315 PHE   B CG  1 
ATOM   5316 C CD1 . PHE   B 1 315 ? -68.70219  -5.69969  -101.88669 1.000 19.11642  ? 315 PHE   B CD1 1 
ATOM   5317 C CD2 . PHE   B 1 315 ? -70.88990  -6.41064  -101.22985 1.000 10.82999  ? 315 PHE   B CD2 1 
ATOM   5318 C CE1 . PHE   B 1 315 ? -68.86554  -6.28715  -103.13118 1.000 15.72439  ? 315 PHE   B CE1 1 
ATOM   5319 C CE2 . PHE   B 1 315 ? -71.07331  -7.00904  -102.47850 1.000 15.62353  ? 315 PHE   B CE2 1 
ATOM   5320 C CZ  . PHE   B 1 315 ? -70.05440  -6.94548  -103.43205 1.000 23.95611  ? 315 PHE   B CZ  1 
ATOM   5321 N N   . ASP   B 1 316 ? -67.54888  -4.68039  -97.03432  1.000 20.69510  ? 316 ASP   B N   1 
ATOM   5322 C CA  . ASP   B 1 316 ? -67.24775  -4.03814  -95.76657  1.000 23.01266  ? 316 ASP   B CA  1 
ATOM   5323 C C   . ASP   B 1 316 ? -67.80132  -2.61512  -95.78277  1.000 19.79681  ? 316 ASP   B C   1 
ATOM   5324 O O   . ASP   B 1 316 ? -68.45370  -2.19433  -96.74269  1.000 23.26906  ? 316 ASP   B O   1 
ATOM   5325 C CB  . ASP   B 1 316 ? -65.74362  -4.09413  -95.46489  1.000 19.44517  ? 316 ASP   B CB  1 
ATOM   5326 C CG  . ASP   B 1 316 ? -64.89526  -3.26766  -96.43417  1.000 23.57318  ? 316 ASP   B CG  1 
ATOM   5327 O OD1 . ASP   B 1 316 ? -65.42619  -2.37060  -97.13483  1.000 21.85615  ? 316 ASP   B OD1 1 
ATOM   5328 O OD2 . ASP   B 1 316 ? -63.66283  -3.50888  -96.46969  1.000 23.43197  ? 316 ASP   B OD2 1 
ATOM   5329 N N   . GLU   B 1 317 ? -67.53828  -1.86188  -94.70378  1.000 24.70799  ? 317 GLU   B N   1 
ATOM   5330 C CA  . GLU   B 1 317 ? -68.11378  -0.52484  -94.55988  1.000 20.84408  ? 317 GLU   B CA  1 
ATOM   5331 C C   . GLU   B 1 317 ? -67.58427  0.45566   -95.59068  1.000 20.04122  ? 317 GLU   B C   1 
ATOM   5332 O O   . GLU   B 1 317 ? -68.19057  1.51195   -95.78181  1.000 23.39221  ? 317 GLU   B O   1 
ATOM   5333 C CB  . GLU   B 1 317 ? -67.85110  0.02824   -93.16491  1.000 18.16439  ? 317 GLU   B CB  1 
ATOM   5334 C CG  . GLU   B 1 317 ? -68.61958  -0.68358  -92.07438  1.000 18.05522  ? 317 GLU   B CG  1 
ATOM   5335 C CD  . GLU   B 1 317 ? -68.01348  -0.43389  -90.70721  1.000 35.02838  ? 317 GLU   B CD  1 
ATOM   5336 O OE1 . GLU   B 1 317 ? -67.19534  -1.27639  -90.25839  1.000 28.71332  ? 317 GLU   B OE1 1 
ATOM   5337 O OE2 . GLU   B 1 317 ? -68.34369  0.61506   -90.09522  1.000 30.10777  ? 317 GLU   B OE2 1 
ATOM   5338 N N   . GLN   B 1 318 ? -66.46934  0.13923   -96.24250  1.000 19.20128  ? 318 GLN   B N   1 
ATOM   5339 C CA  . GLN   B 1 318 ? -65.93617  0.94678   -97.32599  1.000 19.47406  ? 318 GLN   B CA  1 
ATOM   5340 C C   . GLN   B 1 318 ? -66.37980  0.43585   -98.68022  1.000 25.43161  ? 318 GLN   B C   1 
ATOM   5341 O O   . GLN   B 1 318 ? -65.83457  0.86404   -99.70285  1.000 28.08582  ? 318 GLN   B O   1 
ATOM   5342 C CB  . GLN   B 1 318 ? -64.40617  0.98176   -97.25760  1.000 26.73799  ? 318 GLN   B CB  1 
ATOM   5343 C CG  . GLN   B 1 318 ? -63.84396  1.80824   -96.10509  1.000 19.47345  ? 318 GLN   B CG  1 
ATOM   5344 C CD  . GLN   B 1 318 ? -64.12978  1.21374   -94.73292  1.000 35.06443  ? 318 GLN   B CD  1 
ATOM   5345 O OE1 . GLN   B 1 318 ? -63.81818  0.04499   -94.47183  1.000 35.26068  ? 318 GLN   B OE1 1 
ATOM   5346 N NE2 . GLN   B 1 318 ? -64.71873  2.02276   -93.84035  1.000 25.46336  ? 318 GLN   B NE2 1 
ATOM   5347 N N   . HIS   B 1 319 ? -67.34685  -0.48215  -98.70013  1.000 24.72017  ? 319 HIS   B N   1 
ATOM   5348 C CA  . HIS   B 1 319 ? -67.89818  -1.09059  -99.90975  1.000 25.82164  ? 319 HIS   B CA  1 
ATOM   5349 C C   . HIS   B 1 319 ? -66.86928  -1.92420  -100.65952 1.000 22.68592  ? 319 HIS   B C   1 
ATOM   5350 O O   . HIS   B 1 319 ? -67.02961  -2.18341  -101.85716 1.000 23.88453  ? 319 HIS   B O   1 
ATOM   5351 C CB  . HIS   B 1 319 ? -68.51976  -0.04849  -100.84370 1.000 20.50608  ? 319 HIS   B CB  1 
ATOM   5352 C CG  . HIS   B 1 319 ? -69.61579  0.75439   -100.20855 1.000 29.33283  ? 319 HIS   B CG  1 
ATOM   5353 N ND1 . HIS   B 1 319 ? -70.34830  1.69445   -100.90142 1.000 29.84633  ? 319 HIS   B ND1 1 
ATOM   5354 C CD2 . HIS   B 1 319 ? -70.09710  0.76307   -98.94356  1.000 18.50768  ? 319 HIS   B CD2 1 
ATOM   5355 C CE1 . HIS   B 1 319 ? -71.23725  2.24068   -100.09268 1.000 22.92281  ? 319 HIS   B CE1 1 
ATOM   5356 N NE2 . HIS   B 1 319 ? -71.10196  1.69627   -98.89792  1.000 18.99576  ? 319 HIS   B NE2 1 
ATOM   5357 N N   . LYS   B 1 320 ? -65.85448  -2.35483  -99.98801  1.000 17.31427  ? 320 LYS   B N   1 
ATOM   5358 C CA  . LYS   B 1 320 ? -64.82895  -3.23127  -100.52958 1.000 19.92818  ? 320 LYS   B CA  1 
ATOM   5359 C C   . LYS   B 1 320 ? -65.19665  -4.68602  -100.26269 1.000 21.10128  ? 320 LYS   B C   1 
ATOM   5360 O O   . LYS   B 1 320 ? -65.88060  -4.98662  -99.28307  1.000 24.69130  ? 320 LYS   B O   1 
ATOM   5361 C CB  . LYS   B 1 320 ? -63.47452  -2.92323  -99.89352  1.000 27.22779  ? 320 LYS   B CB  1 
ATOM   5362 C CG  . LYS   B 1 320 ? -63.00016  -1.49811  -100.10760 1.000 26.94364  ? 320 LYS   B CG  1 
ATOM   5363 C CD  . LYS   B 1 320 ? -62.97578  -1.14610  -101.58280 1.000 31.82292  ? 320 LYS   B CD  1 
ATOM   5364 C CE  . LYS   B 1 320 ? -62.25044  0.17757   -101.84387 1.000 33.88148  ? 320 LYS   B CE  1 
ATOM   5365 N NZ  . LYS   B 1 320 ? -62.12933  0.42557   -103.32344 1.000 35.69395  ? 320 LYS   B NZ  1 
ATOM   5366 N N   . PRO   B 1 321 ? -64.76408  -5.61576  -101.10951 1.000 22.59813  ? 321 PRO   B N   1 
ATOM   5367 C CA  . PRO   B 1 321 ? -65.12203  -7.02160  -100.89582 1.000 20.09370  ? 321 PRO   B CA  1 
ATOM   5368 C C   . PRO   B 1 321 ? -64.34373  -7.63511  -99.74293  1.000 27.54316  ? 321 PRO   B C   1 
ATOM   5369 O O   . PRO   B 1 321 ? -63.13573  -7.42784  -99.58791  1.000 25.14111  ? 321 PRO   B O   1 
ATOM   5370 C CB  . PRO   B 1 321 ? -64.76028  -7.68439  -102.22782 1.000 20.97660  ? 321 PRO   B CB  1 
ATOM   5371 C CG  . PRO   B 1 321 ? -63.69703  -6.81586  -102.78075 1.000 19.12213  ? 321 PRO   B CG  1 
ATOM   5372 C CD  . PRO   B 1 321 ? -64.04130  -5.42181  -102.37366 1.000 24.08843  ? 321 PRO   B CD  1 
ATOM   5373 N N   . LYS   B 1 322 ? -65.05946  -8.37775  -98.92507  1.000 18.55454  ? 322 LYS   B N   1 
ATOM   5374 C CA  . LYS   B 1 322 ? -64.47999  -9.12139  -97.82322  1.000 16.72630  ? 322 LYS   B CA  1 
ATOM   5375 C C   . LYS   B 1 322 ? -64.11321  -10.51900 -98.29104  1.000 20.08935  ? 322 LYS   B C   1 
ATOM   5376 O O   . LYS   B 1 322 ? -64.53040  -10.97316 -99.36683  1.000 16.16268  ? 322 LYS   B O   1 
ATOM   5377 C CB  . LYS   B 1 322 ? -65.47752  -9.18046  -96.66510  1.000 20.72387  ? 322 LYS   B CB  1 
ATOM   5378 C CG  . LYS   B 1 322 ? -65.86078  -7.83486  -96.07231  1.000 20.92614  ? 322 LYS   B CG  1 
ATOM   5379 C CD  . LYS   B 1 322 ? -67.21589  -7.90066  -95.33285  1.000 23.77176  ? 322 LYS   B CD  1 
ATOM   5380 C CE  . LYS   B 1 322 ? -67.20467  -8.87706  -94.14844  1.000 17.11339  ? 322 LYS   B CE  1 
ATOM   5381 N NZ  . LYS   B 1 322 ? -68.51256  -8.92571  -93.41474  1.000 13.40876  ? 322 LYS   B NZ  1 
ATOM   5382 N N   . PRO   B 1 323 ? -63.31803  -11.24047 -97.50617  1.000 17.16518  ? 323 PRO   B N   1 
ATOM   5383 C CA  . PRO   B 1 323 ? -63.06478  -12.64670 -97.83935  1.000 15.79294  ? 323 PRO   B CA  1 
ATOM   5384 C C   . PRO   B 1 323 ? -64.33576  -13.43333 -98.12010  1.000 17.71863  ? 323 PRO   B C   1 
ATOM   5385 O O   . PRO   B 1 323 ? -64.33415  -14.31088 -99.00314  1.000 16.47102  ? 323 PRO   B O   1 
ATOM   5386 C CB  . PRO   B 1 323 ? -62.31784  -13.15262 -96.60011  1.000 17.16448  ? 323 PRO   B CB  1 
ATOM   5387 C CG  . PRO   B 1 323 ? -61.53899  -11.95258 -96.15268  1.000 14.75409  ? 323 PRO   B CG  1 
ATOM   5388 C CD  . PRO   B 1 323 ? -62.45669  -10.77377 -96.40355  1.000 19.93296  ? 323 PRO   B CD  1 
ATOM   5389 N N   . ALA   B 1 324 ? -65.43417  -13.11826 -97.42178  1.000 17.50839  ? 324 ALA   B N   1 
ATOM   5390 C CA  . ALA   B 1 324 ? -66.71508  -13.76343 -97.71362  1.000 18.82499  ? 324 ALA   B CA  1 
ATOM   5391 C C   . ALA   B 1 324 ? -67.12969  -13.55837 -99.16701  1.000 14.34117  ? 324 ALA   B C   1 
ATOM   5392 O O   . ALA   B 1 324 ? -67.64371  -14.48810 -99.80856  1.000 18.30478  ? 324 ALA   B O   1 
ATOM   5393 C CB  . ALA   B 1 324 ? -67.80718  -13.23795 -96.77935  1.000 14.67177  ? 324 ALA   B CB  1 
ATOM   5394 N N   . PHE   B 1 325 ? -66.93076  -12.34654 -99.70036  1.000 12.68844  ? 325 PHE   B N   1 
ATOM   5395 C CA  . PHE   B 1 325 ? -67.24040  -12.10331 -101.10633 1.000 17.18386  ? 325 PHE   B CA  1 
ATOM   5396 C C   . PHE   B 1 325 ? -66.48692  -13.06909 -102.00857 1.000 23.00867  ? 325 PHE   B C   1 
ATOM   5397 O O   . PHE   B 1 325 ? -67.07789  -13.69896 -102.89474 1.000 19.94699  ? 325 PHE   B O   1 
ATOM   5398 C CB  . PHE   B 1 325 ? -66.90412  -10.66684 -101.50614 1.000 14.46088  ? 325 PHE   B CB  1 
ATOM   5399 C CG  . PHE   B 1 325 ? -67.03727  -10.41764 -102.98912 1.000 21.73227  ? 325 PHE   B CG  1 
ATOM   5400 C CD1 . PHE   B 1 325 ? -68.26623  -10.03693 -103.53726 1.000 22.83405  ? 325 PHE   B CD1 1 
ATOM   5401 C CD2 . PHE   B 1 325 ? -65.94410  -10.58876 -103.84839 1.000 23.78141  ? 325 PHE   B CD2 1 
ATOM   5402 C CE1 . PHE   B 1 325 ? -68.40683  -9.81485  -104.91618 1.000 19.80650  ? 325 PHE   B CE1 1 
ATOM   5403 C CE2 . PHE   B 1 325 ? -66.07088  -10.37760 -105.22413 1.000 19.36685  ? 325 PHE   B CE2 1 
ATOM   5404 C CZ  . PHE   B 1 325 ? -67.31064  -9.98371  -105.75769 1.000 24.78055  ? 325 PHE   B CZ  1 
ATOM   5405 N N   . TRP   B 1 326 ? -65.16748  -13.17672 -101.81114 1.000 19.68120  ? 326 TRP   B N   1 
ATOM   5406 C CA  . TRP   B 1 326 ? -64.34988  -14.00050 -102.69763 1.000 21.25918  ? 326 TRP   B CA  1 
ATOM   5407 C C   . TRP   B 1 326 ? -64.66780  -15.48785 -102.54507 1.000 17.98421  ? 326 TRP   B C   1 
ATOM   5408 O O   . TRP   B 1 326 ? -64.71392  -16.21906 -103.54081 1.000 21.26330  ? 326 TRP   B O   1 
ATOM   5409 C CB  . TRP   B 1 326 ? -62.86812  -13.70302 -102.44649 1.000 22.36544  ? 326 TRP   B CB  1 
ATOM   5410 C CG  . TRP   B 1 326 ? -62.54665  -12.33488 -102.91112 1.000 17.69963  ? 326 TRP   B CG  1 
ATOM   5411 C CD1 . TRP   B 1 326 ? -62.21501  -11.26199 -102.14654 1.000 18.52959  ? 326 TRP   B CD1 1 
ATOM   5412 C CD2 . TRP   B 1 326 ? -62.59407  -11.87191 -104.25815 1.000 21.74116  ? 326 TRP   B CD2 1 
ATOM   5413 N NE1 . TRP   B 1 326 ? -62.03033  -10.15570 -102.93706 1.000 13.79048  ? 326 TRP   B NE1 1 
ATOM   5414 C CE2 . TRP   B 1 326 ? -62.24746  -10.50821 -104.24196 1.000 19.66231  ? 326 TRP   B CE2 1 
ATOM   5415 C CE3 . TRP   B 1 326 ? -62.87501  -12.48702 -105.48721 1.000 18.71553  ? 326 TRP   B CE3 1 
ATOM   5416 C CZ2 . TRP   B 1 326 ? -62.17937  -9.74394  -105.40416 1.000 22.45800  ? 326 TRP   B CZ2 1 
ATOM   5417 C CZ3 . TRP   B 1 326 ? -62.80534  -11.73086 -106.63746 1.000 18.48107  ? 326 TRP   B CZ3 1 
ATOM   5418 C CH2 . TRP   B 1 326 ? -62.46273  -10.37292 -106.59073 1.000 24.74784  ? 326 TRP   B CH2 1 
ATOM   5419 N N   . ARG   B 1 327 ? -64.93233  -15.95767 -101.32242 1.000 14.95600  ? 327 ARG   B N   1 
ATOM   5420 C CA  . ARG   B 1 327 ? -65.30726  -17.36381 -101.19239 1.000 15.56123  ? 327 ARG   B CA  1 
ATOM   5421 C C   . ARG   B 1 327 ? -66.69443  -17.63098 -101.76918 1.000 21.53128  ? 327 ARG   B C   1 
ATOM   5422 O O   . ARG   B 1 327 ? -66.93565  -18.72025 -102.29811 1.000 24.38956  ? 327 ARG   B O   1 
ATOM   5423 C CB  . ARG   B 1 327 ? -65.24387  -17.82323 -99.73000  1.000 19.21426  ? 327 ARG   B CB  1 
ATOM   5424 C CG  . ARG   B 1 327 ? -63.88687  -17.67623 -99.07534  1.000 23.46597  ? 327 ARG   B CG  1 
ATOM   5425 C CD  . ARG   B 1 327 ? -62.78142  -18.24934 -99.96613  1.000 28.64346  ? 327 ARG   B CD  1 
ATOM   5426 N NE  . ARG   B 1 327 ? -62.82124  -19.71083 -99.99927  1.000 27.76924  ? 327 ARG   B NE  1 
ATOM   5427 C CZ  . ARG   B 1 327 ? -62.39323  -20.44862 -101.01995 1.000 27.21952  ? 327 ARG   B CZ  1 
ATOM   5428 N NH1 . ARG   B 1 327 ? -61.90094  -19.85984 -102.10493 1.000 25.42684  ? 327 ARG   B NH1 1 
ATOM   5429 N NH2 . ARG   B 1 327 ? -62.46364  -21.77612 -100.95786 1.000 23.82142  ? 327 ARG   B NH2 1 
ATOM   5430 N N   . ALA   B 1 328 ? -67.61529  -16.65768 -101.69552 1.000 16.96877  ? 328 ALA   B N   1 
ATOM   5431 C CA  . ALA   B 1 328 ? -68.95582  -16.88874 -102.22898 1.000 20.83106  ? 328 ALA   B CA  1 
ATOM   5432 C C   . ALA   B 1 328 ? -68.93850  -17.02599 -103.74462 1.000 20.06225  ? 328 ALA   B C   1 
ATOM   5433 O O   . ALA   B 1 328 ? -69.61758  -17.90009 -104.29380 1.000 25.68674  ? 328 ALA   B O   1 
ATOM   5434 C CB  . ALA   B 1 328 ? -69.91319  -15.76749 -101.81476 1.000 20.09391  ? 328 ALA   B CB  1 
ATOM   5435 N N   . VAL   B 1 329 ? -68.18454  -16.16724 -104.44221 1.000 19.46420  ? 329 VAL   B N   1 
ATOM   5436 C CA  . VAL   B 1 329 ? -68.15074  -16.22738 -105.90759 1.000 25.51027  ? 329 VAL   B CA  1 
ATOM   5437 C C   . VAL   B 1 329 ? -67.23191  -17.31628 -106.43475 1.000 27.10191  ? 329 VAL   B C   1 
ATOM   5438 O O   . VAL   B 1 329 ? -67.20578  -17.56047 -107.64882 1.000 26.54000  ? 329 VAL   B O   1 
ATOM   5439 C CB  . VAL   B 1 329 ? -67.70456  -14.89417 -106.53766 1.000 20.44045  ? 329 VAL   B CB  1 
ATOM   5440 C CG1 . VAL   B 1 329 ? -68.61411  -13.76592 -106.06599 1.000 23.10291  ? 329 VAL   B CG1 1 
ATOM   5441 C CG2 . VAL   B 1 329 ? -66.26121  -14.60197 -106.18145 1.000 19.14853  ? 329 VAL   B CG2 1 
ATOM   5442 N N   . SER   B 1 330 ? -66.47305  -17.97168 -105.55911 1.000 27.22123  ? 330 SER   B N   1 
ATOM   5443 C CA  . SER   B 1 330 ? -65.54416  -19.00966 -105.97233 1.000 24.69942  ? 330 SER   B CA  1 
ATOM   5444 C C   . SER   B 1 330 ? -66.22237  -20.35301 -106.20176 1.000 23.30892  ? 330 SER   B C   1 
ATOM   5445 O O   . SER   B 1 330 ? -65.58806  -21.26140 -106.74675 1.000 28.52653  ? 330 SER   B O   1 
ATOM   5446 C CB  . SER   B 1 330 ? -64.44597  -19.16269 -104.91788 1.000 24.77505  ? 330 SER   B CB  1 
ATOM   5447 O OG  . SER   B 1 330 ? -64.84476  -20.03951 -103.88049 1.000 18.53596  ? 330 SER   B OG  1 
ATOM   5448 N N   . VAL   B 1 331 ? -67.48371  -20.49982 -105.80373 1.000 18.75989  ? 331 VAL   B N   1 
ATOM   5449 C CA  . VAL   B 1 331 ? -68.15824  -21.78380 -105.87119 1.000 17.58785  ? 331 VAL   B CA  1 
ATOM   5450 C C   . VAL   B 1 331 ? -68.60340  -22.13887 -107.28852 1.000 32.01817  ? 331 VAL   B C   1 
ATOM   5451 O O   . VAL   B 1 331 ? -69.01917  -23.27637 -107.50882 1.000 26.56008  ? 331 VAL   B O   1 
ATOM   5452 C CB  . VAL   B 1 331 ? -69.36855  -21.80614 -104.92007 1.000 28.18488  ? 331 VAL   B CB  1 
ATOM   5453 C CG1 . VAL   B 1 331 ? -68.92961  -21.48841 -103.48440 1.000 21.61665  ? 331 VAL   B CG1 1 
ATOM   5454 C CG2 . VAL   B 1 331 ? -70.45896  -20.82857 -105.41331 1.000 22.90287  ? 331 VAL   B CG2 1 
ATOM   5455 O OXT . VAL   B 1 331 ? -68.59549  -21.31998 -108.22197 1.000 41.35404  ? 331 VAL   B OXT 1 
HETATM 5456 C C1  . A1ID6 C 2 .   ? -87.13428  -10.19874 -91.08608  1.000 22.80746  ? 1   A1ID6 C C1  1 
HETATM 5457 C C2  . A1ID6 C 2 .   ? -88.39210  -9.37738  -91.40717  1.000 19.80830  ? 1   A1ID6 C C2  1 
HETATM 5458 C C3  . A1ID6 C 2 .   ? -87.95165  -8.02389  -91.93662  1.000 20.89192  ? 1   A1ID6 C C3  1 
HETATM 5459 C C4  . A1ID6 C 2 .   ? -87.18028  -7.37487  -90.81193  1.000 11.99573  ? 1   A1ID6 C C4  1 
HETATM 5460 C C5  . A1ID6 C 2 .   ? -85.94699  -8.22422  -90.54497  1.000 16.85048  ? 1   A1ID6 C C5  1 
HETATM 5461 O O2  . A1ID6 C 2 .   ? -89.15945  -10.04519 -92.39377  1.000 13.58550  ? 1   A1ID6 C O2  1 
HETATM 5462 O O3  . A1ID6 C 2 .   ? -89.05507  -7.20977  -92.31738  1.000 17.17453  ? 1   A1ID6 C O3  1 
HETATM 5463 O O4  . A1ID6 C 2 .   ? -86.77067  -6.08524  -91.22167  1.000 17.80381  ? 1   A1ID6 C O4  1 
HETATM 5464 O O5  . A1ID6 C 2 .   ? -86.34643  -9.52722  -90.09595  1.000 15.89683  ? 1   A1ID6 C O5  1 
HETATM 5465 F F1  . A1ID6 C 2 .   ? -86.37842  -10.40041 -92.22290  1.000 13.60787  ? 1   A1ID6 C F1  1 
HETATM 5466 C C1  . XYP   C 2 .   ? -86.41477  -5.29692  -90.08663  1.000 14.00541  ? 2   XYP   C C1  1 
HETATM 5467 C C2  . XYP   C 2 .   ? -85.71987  -4.05742  -90.61664  1.000 15.16516  ? 2   XYP   C C2  1 
HETATM 5468 C C3  . XYP   C 2 .   ? -85.56431  -2.98041  -89.54671  1.000 15.11738  ? 2   XYP   C C3  1 
HETATM 5469 C C4  . XYP   C 2 .   ? -86.90314  -2.72592  -88.84310  1.000 16.61065  ? 2   XYP   C C4  1 
HETATM 5470 C C5  . XYP   C 2 .   ? -87.47173  -4.03265  -88.29586  1.000 12.97711  ? 2   XYP   C C5  1 
HETATM 5471 O O2  . XYP   C 2 .   ? -84.43755  -4.43804  -91.13968  1.000 12.89589  ? 2   XYP   C O2  1 
HETATM 5472 O O3  . XYP   C 2 .   ? -85.05472  -1.79566  -90.17052  1.000 12.23237  ? 2   XYP   C O3  1 
HETATM 5473 O O4  . XYP   C 2 .   ? -86.71647  -1.84541  -87.72922  1.000 22.65621  ? 2   XYP   C O4  1 
HETATM 5474 O O5  . XYP   C 2 .   ? -87.60261  -4.98602  -89.35510  1.000 17.23074  ? 2   XYP   C O5  1 
HETATM 5475 C C1  . A1ID6 D 3 .   ? -34.27075  -3.05081  -118.85567 0.912 92.16738  ? 1   A1ID6 D C1  1 
HETATM 5476 C C2  . A1ID6 D 3 .   ? -33.14880  -3.88973  -118.21618 0.912 88.19369  ? 1   A1ID6 D C2  1 
HETATM 5477 C C3  . A1ID6 D 3 .   ? -33.58000  -4.99003  -117.22043 0.912 71.95355  ? 1   A1ID6 D C3  1 
HETATM 5478 C C4  . A1ID6 D 3 .   ? -34.96209  -4.79408  -116.57358 0.912 66.38053  ? 1   A1ID6 D C4  1 
HETATM 5479 C C5  . A1ID6 D 3 .   ? -35.91442  -4.22901  -117.62094 0.912 61.44054  ? 1   A1ID6 D C5  1 
HETATM 5480 O O2  . A1ID6 D 3 .   ? -32.35009  -4.46810  -119.26841 0.912 70.58440  ? 1   A1ID6 D O2  1 
HETATM 5481 O O3  . A1ID6 D 3 .   ? -32.58027  -5.06750  -116.19035 0.912 73.04958  ? 1   A1ID6 D O3  1 
HETATM 5482 O O4  . A1ID6 D 3 .   ? -35.53780  -6.00563  -116.03452 0.912 58.13663  ? 1   A1ID6 D O4  1 
HETATM 5483 O O5  . A1ID6 D 3 .   ? -35.43324  -2.94953  -118.02699 0.912 77.75029  ? 1   A1ID6 D O5  1 
HETATM 5484 F F1  . A1ID6 D 3 .   ? -34.59465  -3.50832  -120.11311 0.912 77.98662  ? 1   A1ID6 D F1  1 
HETATM 5485 C C1  . XYP   D 3 .   ? -35.07337  -6.43310  -114.73683 0.912 53.46901  ? 2   XYP   D C1  1 
HETATM 5486 C C2  . XYP   D 3 .   ? -36.14300  -7.27076  -114.00742 0.912 42.81080  ? 2   XYP   D C2  1 
HETATM 5487 C C3  . XYP   D 3 .   ? -35.59045  -7.93765  -112.73960 0.912 46.06375  ? 2   XYP   D C3  1 
HETATM 5488 C C4  . XYP   D 3 .   ? -34.27974  -8.64584  -113.05584 0.912 39.74663  ? 2   XYP   D C4  1 
HETATM 5489 C C5  . XYP   D 3 .   ? -33.28006  -7.67063  -113.66476 0.912 49.66795  ? 2   XYP   D C5  1 
HETATM 5490 O O2  . XYP   D 3 .   ? -37.28877  -6.47197  -113.65836 0.912 37.48274  ? 2   XYP   D O2  1 
HETATM 5491 O O3  . XYP   D 3 .   ? -36.50455  -8.89180  -112.15443 0.912 32.95096  ? 2   XYP   D O3  1 
HETATM 5492 O O4  . XYP   D 3 .   ? -33.74053  -9.20380  -111.86812 0.912 46.99328  ? 2   XYP   D O4  1 
HETATM 5493 O O5  . XYP   D 3 .   ? -33.84006  -7.16394  -114.88113 0.912 63.22459  ? 2   XYP   D O5  1 
HETATM 5494 C C1  . XYP   D 3 .   ? -33.22115  -10.52193 -112.04242 0.912 41.34068  ? 3   XYP   D C1  1 
HETATM 5495 C C2  . XYP   D 3 .   ? -31.90703  -10.59189 -111.25151 0.912 38.60668  ? 3   XYP   D C2  1 
HETATM 5496 C C3  . XYP   D 3 .   ? -31.45224  -12.01537 -110.91671 0.912 41.34824  ? 3   XYP   D C3  1 
HETATM 5497 C C4  . XYP   D 3 .   ? -32.64598  -12.83682 -110.45859 0.912 28.05131  ? 3   XYP   D C4  1 
HETATM 5498 C C5  . XYP   D 3 .   ? -33.69174  -12.79982 -111.56209 0.912 32.31656  ? 3   XYP   D C5  1 
HETATM 5499 O O2  . XYP   D 3 .   ? -30.90019  -9.89688  -112.00750 0.912 43.18958  ? 3   XYP   D O2  1 
HETATM 5500 O O3  . XYP   D 3 .   ? -30.45256  -12.01122 -109.87645 0.912 50.42019  ? 3   XYP   D O3  1 
HETATM 5501 O O4  . XYP   D 3 .   ? -32.24213  -14.17016 -110.10708 0.912 30.79545  ? 3   XYP   D O4  1 
HETATM 5502 O O5  . XYP   D 3 .   ? -34.21381  -11.46838 -111.62006 0.912 31.89051  ? 3   XYP   D O5  1 
HETATM 5503 C C1  . XYP   D 3 .   ? -33.30103  -15.15534 -109.96810 0.912 26.41092  ? 4   XYP   D C1  1 
HETATM 5504 C C2  . XYP   D 3 .   ? -32.70270  -16.53621 -109.66596 0.912 19.68889  ? 4   XYP   D C2  1 
HETATM 5505 C C3  . XYP   D 3 .   ? -32.78707  -16.90572 -108.19013 0.912 15.40073  ? 4   XYP   D C3  1 
HETATM 5506 C C4  . XYP   D 3 .   ? -32.58811  -15.65468 -107.36207 0.912 17.74487  ? 4   XYP   D C4  1 
HETATM 5507 C C5  . XYP   D 3 .   ? -33.68387  -14.62607 -107.65046 0.912 13.47918  ? 4   XYP   D C5  1 
HETATM 5508 O O2  . XYP   D 3 .   ? -33.36186  -17.53610 -110.42586 0.912 13.34768  ? 4   XYP   D O2  1 
HETATM 5509 O O3  . XYP   D 3 .   ? -31.75233  -17.83258 -107.89499 0.912 15.25071  ? 4   XYP   D O3  1 
HETATM 5510 O O4  . XYP   D 3 .   ? -32.55978  -15.96701 -105.98033 0.912 17.78787  ? 4   XYP   D O4  1 
HETATM 5511 O O5  . XYP   D 3 .   ? -34.24464  -14.83218 -108.94973 0.912 14.83350  ? 4   XYP   D O5  1 
HETATM 5512 C C1  . XYP   D 3 .   ? -31.90123  -14.91421 -105.28478 0.912 14.50094  ? 5   XYP   D C1  1 
HETATM 5513 C C2  . XYP   D 3 .   ? -31.99774  -15.18041 -103.78697 0.912 13.55588  ? 5   XYP   D C2  1 
HETATM 5514 C C3  . XYP   D 3 .   ? -31.12400  -14.18909 -103.03026 0.912 16.44196  ? 5   XYP   D C3  1 
HETATM 5515 C C4  . XYP   D 3 .   ? -29.75295  -14.45241 -103.63605 0.912 25.24146  ? 5   XYP   D C4  1 
HETATM 5516 C C5  . XYP   D 3 .   ? -29.69302  -13.95532 -105.05908 0.912 13.49023  ? 5   XYP   D C5  1 
HETATM 5517 O O2  . XYP   D 3 .   ? -33.35503  -15.10809 -103.35997 0.912 10.21344  ? 5   XYP   D O2  1 
HETATM 5518 O O3  . XYP   D 3 .   ? -31.17617  -14.52513 -101.65052 0.912 15.06190  ? 5   XYP   D O3  1 
HETATM 5519 O O4  . XYP   D 3 .   ? -28.59283  -14.09950 -102.89972 0.912 40.95951  ? 5   XYP   D O4  1 
HETATM 5520 O O5  . XYP   D 3 .   ? -30.54711  -14.85556 -105.75833 0.912 18.45283  ? 5   XYP   D O5  1 
HETATM 5521 C C1  . XYP   D 3 .   ? -28.56346  -12.91923 -102.13500 0.912 45.58756  ? 6   XYP   D C1  1 
HETATM 5522 C C2  . XYP   D 3 .   ? -27.30607  -13.15436 -101.29191 0.912 54.76759  ? 6   XYP   D C2  1 
HETATM 5523 C C3  . XYP   D 3 .   ? -26.39989  -11.92720 -101.19237 0.912 57.97496  ? 6   XYP   D C3  1 
HETATM 5524 C C4  . XYP   D 3 .   ? -26.14451  -11.27344 -102.54600 0.912 61.62292  ? 6   XYP   D C4  1 
HETATM 5525 C C5  . XYP   D 3 .   ? -27.13597  -11.73175 -103.60889 0.912 63.14377  ? 6   XYP   D C5  1 
HETATM 5526 O O2  . XYP   D 3 .   ? -27.68714  -13.63690 -99.99235  0.912 61.10813  ? 6   XYP   D O2  1 
HETATM 5527 O O3  . XYP   D 3 .   ? -25.13413  -12.31935 -100.65828 0.912 63.24262  ? 6   XYP   D O3  1 
HETATM 5528 O O4  . XYP   D 3 .   ? -26.25334  -9.85297  -102.39600 0.912 70.11903  ? 6   XYP   D O4  1 
HETATM 5529 O O5  . XYP   D 3 .   ? -28.43839  -11.80942 -103.02204 0.912 61.66618  ? 6   XYP   D O5  1 
HETATM 5530 O O   . HOH   E 4 .   ? -44.82242  -30.73901 -111.33972 1.000 36.05075  ? 401 HOH   A O   1 
HETATM 5531 O O   . HOH   E 4 .   ? -10.00253  -28.10771 -124.59367 1.000 39.75868  ? 402 HOH   A O   1 
HETATM 5532 O O   . HOH   E 4 .   ? -51.49571  -28.78454 -114.38843 1.000 14.50991  ? 403 HOH   A O   1 
HETATM 5533 O O   . HOH   E 4 .   ? -9.87604   -26.79671 -101.04426 1.000 33.42453  ? 404 HOH   A O   1 
HETATM 5534 O O   . HOH   E 4 .   ? -8.06987   -28.31583 -110.37937 1.000 39.21963  ? 405 HOH   A O   1 
HETATM 5535 O O   . HOH   E 4 .   ? -29.65323  -3.15104  -107.71169 1.000 31.97805  ? 406 HOH   A O   1 
HETATM 5536 O O   . HOH   E 4 .   ? -10.18484  -27.55594 -103.99821 1.000 35.85980  ? 407 HOH   A O   1 
HETATM 5537 O O   . HOH   E 4 .   ? -33.86183  -37.04492 -97.12600  1.000 39.36602  ? 408 HOH   A O   1 
HETATM 5538 O O   . HOH   E 4 .   ? -43.04754  -28.45541 -108.07486 1.000 11.46520  ? 409 HOH   A O   1 
HETATM 5539 O O   . HOH   E 4 .   ? -60.99484  -18.76302 -112.88634 1.000 28.29456  ? 410 HOH   A O   1 
HETATM 5540 O O   . HOH   E 4 .   ? -22.35045  -12.37472 -117.42998 1.000 38.45562  ? 411 HOH   A O   1 
HETATM 5541 O O   . HOH   E 4 .   ? -50.78562  -7.17877  -92.87818  1.000 38.71197  ? 412 HOH   A O   1 
HETATM 5542 O O   . HOH   E 4 .   ? -59.37412  -27.15133 -112.03268 1.000 33.88955  ? 413 HOH   A O   1 
HETATM 5543 O O   . HOH   E 4 .   ? -43.78112  1.68192   -108.66991 1.000 22.37631  ? 414 HOH   A O   1 
HETATM 5544 O O   . HOH   E 4 .   ? -60.02176  -6.89625  -102.56397 1.000 22.53316  ? 415 HOH   A O   1 
HETATM 5545 O O   . HOH   E 4 .   ? -46.01299  -6.35124  -125.52940 1.000 25.11592  ? 416 HOH   A O   1 
HETATM 5546 O O   . HOH   E 4 .   ? -36.55518  -37.29784 -117.56915 1.000 25.89309  ? 417 HOH   A O   1 
HETATM 5547 O O   . HOH   E 4 .   ? -38.47897  -16.80632 -131.66477 1.000 30.65755  ? 418 HOH   A O   1 
HETATM 5548 O O   . HOH   E 4 .   ? -47.36753  -35.70980 -108.80226 1.000 58.29564  ? 419 HOH   A O   1 
HETATM 5549 O O   . HOH   E 4 .   ? -27.24802  -42.96034 -116.37259 1.000 25.77716  ? 420 HOH   A O   1 
HETATM 5550 O O   . HOH   E 4 .   ? -57.92816  -16.06266 -117.49745 1.000 33.27188  ? 421 HOH   A O   1 
HETATM 5551 O O   . HOH   E 4 .   ? -25.90713  -24.81897 -125.88831 1.000 28.77208  ? 422 HOH   A O   1 
HETATM 5552 O O   . HOH   E 4 .   ? -42.74297  -24.49622 -109.55739 1.000 15.25977  ? 423 HOH   A O   1 
HETATM 5553 O O   . HOH   E 4 .   ? -9.46582   -25.92504 -108.15026 1.000 29.32104  ? 424 HOH   A O   1 
HETATM 5554 O O   . HOH   E 4 .   ? -43.41913  -5.25195  -122.59218 1.000 28.89859  ? 425 HOH   A O   1 
HETATM 5555 O O   . HOH   E 4 .   ? -50.90519  -8.73101  -89.69132  1.000 31.55303  ? 426 HOH   A O   1 
HETATM 5556 O O   . HOH   E 4 .   ? -47.24434  -0.17451  -110.38503 1.000 29.37953  ? 427 HOH   A O   1 
HETATM 5557 O O   . HOH   E 4 .   ? -28.70318  -24.94088 -130.04077 1.000 39.58382  ? 428 HOH   A O   1 
HETATM 5558 O O   . HOH   E 4 .   ? -39.95998  -12.64397 -114.57896 1.000 17.87592  ? 429 HOH   A O   1 
HETATM 5559 O O   . HOH   E 4 .   ? -33.41713  -26.38075 -104.97756 1.000 10.85957  ? 430 HOH   A O   1 
HETATM 5560 O O   . HOH   E 4 .   ? -40.70904  -10.00826 -115.73436 1.000 17.60473  ? 431 HOH   A O   1 
HETATM 5561 O O   . HOH   E 4 .   ? -55.01903  -12.50829 -121.75391 1.000 21.56159  ? 432 HOH   A O   1 
HETATM 5562 O O   . HOH   E 4 .   ? -38.36492  -9.56854  -113.50273 1.000 20.05357  ? 433 HOH   A O   1 
HETATM 5563 O O   . HOH   E 4 .   ? -33.16031  5.08972   -104.38489 1.000 35.64825  ? 434 HOH   A O   1 
HETATM 5564 O O   . HOH   E 4 .   ? -19.48347  -17.76327 -105.64746 1.000 25.66714  ? 435 HOH   A O   1 
HETATM 5565 O O   . HOH   E 4 .   ? -59.27781  -1.35245  -101.02755 1.000 38.48782  ? 436 HOH   A O   1 
HETATM 5566 O O   . HOH   E 4 .   ? -53.17409  -9.78800  -93.62489  1.000 30.09278  ? 437 HOH   A O   1 
HETATM 5567 O O   . HOH   E 4 .   ? -36.40751  -10.49006 -96.52338  1.000 23.38365  ? 438 HOH   A O   1 
HETATM 5568 O O   . HOH   E 4 .   ? -33.16381  -35.64032 -109.67983 1.000 15.59043  ? 439 HOH   A O   1 
HETATM 5569 O O   . HOH   E 4 .   ? -40.88058  -15.90323 -97.47402  1.000 12.14844  ? 440 HOH   A O   1 
HETATM 5570 O O   . HOH   E 4 .   ? -39.09731  -36.46083 -112.43502 1.000 26.92452  ? 441 HOH   A O   1 
HETATM 5571 O O   . HOH   E 4 .   ? -15.085    -32.052   -107.956   1.000 20.10494  ? 442 HOH   A O   1 
HETATM 5572 O O   . HOH   E 4 .   ? -30.39886  -22.85819 -104.34112 1.000 11.10149  ? 443 HOH   A O   1 
HETATM 5573 O O   . HOH   E 4 .   ? -26.25350  -17.79225 -116.97372 1.000 19.35439  ? 444 HOH   A O   1 
HETATM 5574 O O   . HOH   E 4 .   ? -39.89793  0.10571   -98.76556  1.000 22.98993  ? 445 HOH   A O   1 
HETATM 5575 O O   . HOH   E 4 .   ? -31.09638  -17.82725 -98.20160  1.000 21.05421  ? 446 HOH   A O   1 
HETATM 5576 O O   . HOH   E 4 .   ? -39.49049  2.43730   -99.93493  1.000 22.51242  ? 447 HOH   A O   1 
HETATM 5577 O O   . HOH   E 4 .   ? -50.23642  -21.38782 -91.33416  1.000 24.54563  ? 448 HOH   A O   1 
HETATM 5578 O O   . HOH   E 4 .   ? -45.08327  -12.55051 -124.08081 1.000 17.76838  ? 449 HOH   A O   1 
HETATM 5579 O O   . HOH   E 4 .   ? -56.81375  -1.84243  -110.05268 1.000 43.47541  ? 450 HOH   A O   1 
HETATM 5580 O O   . HOH   E 4 .   ? -26.09643  -33.37073 -94.00291  1.000 21.12554  ? 451 HOH   A O   1 
HETATM 5581 O O   . HOH   E 4 .   ? -26.04673  -16.86804 -100.87346 1.000 26.01050  ? 452 HOH   A O   1 
HETATM 5582 O O   . HOH   E 4 .   ? -31.59999  -13.87784 -118.46719 1.000 21.57671  ? 453 HOH   A O   1 
HETATM 5583 O O   . HOH   E 4 .   ? -10.58287  -21.05810 -122.25079 1.000 32.09731  ? 454 HOH   A O   1 
HETATM 5584 O O   . HOH   E 4 .   ? -33.50155  -4.81288  -96.87109  1.000 35.79964  ? 455 HOH   A O   1 
HETATM 5585 O O   . HOH   E 4 .   ? -57.97547  -27.56279 -107.91690 1.000 29.24319  ? 456 HOH   A O   1 
HETATM 5586 O O   . HOH   E 4 .   ? -40.13497  -12.92296 -103.02716 1.000 10.52457  ? 457 HOH   A O   1 
HETATM 5587 O O   . HOH   E 4 .   ? -36.51839  -18.46328 -98.14746  1.000 24.61661  ? 458 HOH   A O   1 
HETATM 5588 O O   . HOH   E 4 .   ? -38.50417  -22.94559 -108.03998 1.000 10.53135  ? 459 HOH   A O   1 
HETATM 5589 O O   . HOH   E 4 .   ? -39.33277  -34.05984 -105.73816 1.000 16.50277  ? 460 HOH   A O   1 
HETATM 5590 O O   . HOH   E 4 .   ? -51.40681  -28.49190 -105.54152 1.000 17.53204  ? 461 HOH   A O   1 
HETATM 5591 O O   . HOH   E 4 .   ? -23.81883  -22.36222 -111.83377 1.000 17.01496  ? 462 HOH   A O   1 
HETATM 5592 O O   . HOH   E 4 .   ? -10.38039  -30.12577 -112.73613 1.000 33.38767  ? 463 HOH   A O   1 
HETATM 5593 O O   . HOH   E 4 .   ? -55.39485  -25.71691 -119.63846 1.000 29.89503  ? 464 HOH   A O   1 
HETATM 5594 O O   . HOH   E 4 .   ? -35.37286  -3.57224  -103.20907 1.000 19.57132  ? 465 HOH   A O   1 
HETATM 5595 O O   . HOH   E 4 .   ? -38.89828  -5.23476  -107.41326 1.000 20.71650  ? 466 HOH   A O   1 
HETATM 5596 O O   . HOH   E 4 .   ? -28.23356  -9.42960  -120.70817 1.000 32.50682  ? 467 HOH   A O   1 
HETATM 5597 O O   . HOH   E 4 .   ? -33.26963  -36.09922 -116.80407 1.000 22.07539  ? 468 HOH   A O   1 
HETATM 5598 O O   . HOH   E 4 .   ? -58.41469  -10.13006 -109.61409 1.000 28.62820  ? 469 HOH   A O   1 
HETATM 5599 O O   . HOH   E 4 .   ? -36.03401  -11.61538 -129.87371 1.000 22.42002  ? 470 HOH   A O   1 
HETATM 5600 O O   . HOH   E 4 .   ? -19.23229  -20.21691 -101.37065 1.000 31.47926  ? 471 HOH   A O   1 
HETATM 5601 O O   . HOH   E 4 .   ? -45.02493  -26.39292 -87.43480  1.000 36.35756  ? 472 HOH   A O   1 
HETATM 5602 O O   . HOH   E 4 .   ? -22.75286  -22.50391 -97.92054  1.000 22.95349  ? 473 HOH   A O   1 
HETATM 5603 O O   . HOH   E 4 .   ? -33.38870  -13.57372 -99.43345  1.000 19.88330  ? 474 HOH   A O   1 
HETATM 5604 O O   . HOH   E 4 .   ? -45.06014  -5.16710  -119.56979 1.000 17.13520  ? 475 HOH   A O   1 
HETATM 5605 O O   . HOH   E 4 .   ? -45.93949  -20.87431 -131.02129 1.000 26.55275  ? 476 HOH   A O   1 
HETATM 5606 O O   . HOH   E 4 .   ? -34.62605  -21.92010 -132.88020 1.000 27.93306  ? 477 HOH   A O   1 
HETATM 5607 O O   . HOH   E 4 .   ? -41.00523  -9.26366  -108.51670 1.000 15.88310  ? 478 HOH   A O   1 
HETATM 5608 O O   . HOH   E 4 .   ? -23.54703  -37.05369 -115.57627 1.000 24.12194  ? 479 HOH   A O   1 
HETATM 5609 O O   . HOH   E 4 .   ? -25.10975  -17.20345 -121.50641 1.000 24.97255  ? 480 HOH   A O   1 
HETATM 5610 O O   . HOH   E 4 .   ? -41.05298  -25.44407 -105.32756 1.000 13.99349  ? 481 HOH   A O   1 
HETATM 5611 O O   . HOH   E 4 .   ? -52.65506  -7.38913  -114.61236 1.000 25.70532  ? 482 HOH   A O   1 
HETATM 5612 O O   . HOH   E 4 .   ? -31.61604  -22.26691 -99.57167  1.000 13.19642  ? 483 HOH   A O   1 
HETATM 5613 O O   . HOH   E 4 .   ? -17.17475  -16.63065 -110.80878 1.000 39.79230  ? 484 HOH   A O   1 
HETATM 5614 O O   . HOH   E 4 .   ? -39.79032  -14.16420 -133.51019 1.000 26.81727  ? 485 HOH   A O   1 
HETATM 5615 O O   . HOH   E 4 .   ? -57.91352  -27.99865 -96.97301  1.000 32.05747  ? 486 HOH   A O   1 
HETATM 5616 O O   . HOH   E 4 .   ? -37.76775  -4.61168  -104.92823 1.000 22.99099  ? 487 HOH   A O   1 
HETATM 5617 O O   . HOH   E 4 .   ? -40.76720  -13.44652 -88.88634  1.000 39.84655  ? 488 HOH   A O   1 
HETATM 5618 O O   . HOH   E 4 .   ? -31.84303  -9.95570  -102.21639 1.000 23.59311  ? 489 HOH   A O   1 
HETATM 5619 O O   . HOH   E 4 .   ? -31.21960  -34.90756 -108.01765 1.000 17.48970  ? 490 HOH   A O   1 
HETATM 5620 O O   . HOH   E 4 .   ? -22.02248  -14.70278 -104.23121 1.000 44.64839  ? 491 HOH   A O   1 
HETATM 5621 O O   . HOH   E 4 .   ? -45.24112  -2.89311  -109.13564 1.000 25.36599  ? 492 HOH   A O   1 
HETATM 5622 O O   . HOH   E 4 .   ? -47.59725  -7.49127  -95.89417  1.000 19.24093  ? 493 HOH   A O   1 
HETATM 5623 O O   . HOH   E 4 .   ? -35.99554  -6.83883  -94.50453  1.000 37.15616  ? 494 HOH   A O   1 
HETATM 5624 O O   . HOH   E 4 .   ? -53.11729  -31.46060 -98.67002  1.000 31.56003  ? 495 HOH   A O   1 
HETATM 5625 O O   . HOH   E 4 .   ? -61.80506  -23.22479 -95.83881  1.000 35.99037  ? 496 HOH   A O   1 
HETATM 5626 O O   . HOH   E 4 .   ? -20.61855  -23.99070 -98.53747  1.000 27.27404  ? 497 HOH   A O   1 
HETATM 5627 O O   . HOH   E 4 .   ? -57.31236  -11.62536 -94.40171  1.000 24.78931  ? 498 HOH   A O   1 
HETATM 5628 O O   . HOH   E 4 .   ? -40.59634  -8.84823  -91.16855  1.000 40.46846  ? 499 HOH   A O   1 
HETATM 5629 O O   . HOH   E 4 .   ? -41.72682  -32.34649 -121.61987 1.000 29.51458  ? 500 HOH   A O   1 
HETATM 5630 O O   . HOH   E 4 .   ? -35.71797  -16.93757 -109.04545 1.000 19.71055  ? 501 HOH   A O   1 
HETATM 5631 O O   . HOH   E 4 .   ? -35.89279  -40.00535 -121.20498 1.000 32.63497  ? 502 HOH   A O   1 
HETATM 5632 O O   . HOH   E 4 .   ? -49.57930  -5.89715  -123.71433 1.000 21.41683  ? 503 HOH   A O   1 
HETATM 5633 O O   . HOH   E 4 .   ? -46.10407  0.48376   -107.96890 1.000 27.92994  ? 504 HOH   A O   1 
HETATM 5634 O O   . HOH   E 4 .   ? -40.10445  -7.10301  -125.69120 1.000 37.72061  ? 505 HOH   A O   1 
HETATM 5635 O O   . HOH   E 4 .   ? -48.16990  -16.94063 -128.29784 1.000 20.75273  ? 506 HOH   A O   1 
HETATM 5636 O O   . HOH   E 4 .   ? -11.08635  -32.18479 -114.30427 1.000 42.29566  ? 507 HOH   A O   1 
HETATM 5637 O O   . HOH   E 4 .   ? -42.07065  -7.65398  -114.44957 1.000 20.94699  ? 508 HOH   A O   1 
HETATM 5638 O O   . HOH   E 4 .   ? -8.96880   -23.69943 -109.97424 1.000 38.05482  ? 509 HOH   A O   1 
HETATM 5639 O O   . HOH   E 4 .   ? -24.00988  -38.11530 -96.83617  1.000 17.17574  ? 510 HOH   A O   1 
HETATM 5640 O O   . HOH   E 4 .   ? -14.78693  -17.18355 -105.82668 1.000 26.24090  ? 511 HOH   A O   1 
HETATM 5641 O O   . HOH   E 4 .   ? -37.50016  6.15171   -108.10147 1.000 36.00633  ? 512 HOH   A O   1 
HETATM 5642 O O   . HOH   E 4 .   ? -25.87363  -20.07909 -95.33233  1.000 33.37143  ? 513 HOH   A O   1 
HETATM 5643 O O   . HOH   E 4 .   ? -41.75460  -19.00609 -135.00932 1.000 45.08526  ? 514 HOH   A O   1 
HETATM 5644 O O   . HOH   E 4 .   ? -41.47998  -2.76620  -113.90136 1.000 24.22869  ? 515 HOH   A O   1 
HETATM 5645 O O   . HOH   E 4 .   ? -58.34243  -25.99525 -98.54372  1.000 28.50993  ? 516 HOH   A O   1 
HETATM 5646 O O   . HOH   E 4 .   ? -37.70420  -1.29520  -108.15811 1.000 24.96808  ? 517 HOH   A O   1 
HETATM 5647 O O   . HOH   E 4 .   ? -46.79480  -7.22024  -93.47739  1.000 26.96552  ? 518 HOH   A O   1 
HETATM 5648 O O   . HOH   E 4 .   ? -26.04662  -27.08357 -99.09868  1.000 14.51692  ? 519 HOH   A O   1 
HETATM 5649 O O   . HOH   E 4 .   ? -39.84615  -1.91712  -116.38950 1.000 34.61447  ? 520 HOH   A O   1 
HETATM 5650 O O   . HOH   E 4 .   ? -25.32795  -26.19669 -108.05262 1.000 19.08406  ? 521 HOH   A O   1 
HETATM 5651 O O   . HOH   E 4 .   ? -53.66618  -27.12225 -94.48579  1.000 30.10908  ? 522 HOH   A O   1 
HETATM 5652 O O   . HOH   E 4 .   ? -52.63890  -7.80889  -101.60167 1.000 26.15007  ? 523 HOH   A O   1 
HETATM 5653 O O   . HOH   E 4 .   ? -61.67087  -3.57788  -104.54141 1.000 35.53280  ? 524 HOH   A O   1 
HETATM 5654 O O   . HOH   E 4 .   ? -37.01409  -14.46213 -101.35294 1.000 14.09908  ? 525 HOH   A O   1 
HETATM 5655 O O   . HOH   E 4 .   ? -24.53948  -18.24622 -119.07796 1.000 20.72105  ? 526 HOH   A O   1 
HETATM 5656 O O   . HOH   E 4 .   ? -52.30058  -20.19748 -92.83686  1.000 16.70713  ? 527 HOH   A O   1 
HETATM 5657 O O   . HOH   E 4 .   ? -52.29262  -17.87157 -92.35592  1.000 24.21467  ? 528 HOH   A O   1 
HETATM 5658 O O   . HOH   E 4 .   ? -56.71576  -13.37317 -116.02972 1.000 31.73689  ? 529 HOH   A O   1 
HETATM 5659 O O   . HOH   E 4 .   ? -17.604    -36.639   -106.935   1.000 17.99819  ? 530 HOH   A O   1 
HETATM 5660 O O   . HOH   E 4 .   ? -46.84302  -28.30469 -123.85342 1.000 30.01095  ? 531 HOH   A O   1 
HETATM 5661 O O   . HOH   E 4 .   ? -23.35405  -37.96303 -104.91914 1.000 16.20701  ? 532 HOH   A O   1 
HETATM 5662 O O   . HOH   E 4 .   ? -52.59681  -6.75015  -117.56755 1.000 23.24515  ? 533 HOH   A O   1 
HETATM 5663 O O   . HOH   E 4 .   ? -13.10018  -19.63752 -105.96392 1.000 23.09444  ? 534 HOH   A O   1 
HETATM 5664 O O   . HOH   E 4 .   ? -47.85153  -30.74871 -94.98290  1.000 31.80613  ? 535 HOH   A O   1 
HETATM 5665 O O   . HOH   E 4 .   ? -36.17546  -19.54485 -110.14165 1.000 14.45027  ? 536 HOH   A O   1 
HETATM 5666 O O   . HOH   E 4 .   ? -24.28882  -24.60226 -98.06051  1.000 18.62885  ? 537 HOH   A O   1 
HETATM 5667 O O   . HOH   E 4 .   ? -24.24127  -26.79319 -96.39849  1.000 26.46597  ? 538 HOH   A O   1 
HETATM 5668 O O   . HOH   E 4 .   ? -47.29118  -16.33053 -100.91352 1.000 13.20331  ? 539 HOH   A O   1 
HETATM 5669 O O   . HOH   E 4 .   ? -51.02157  -4.81583  -116.72628 1.000 22.01748  ? 540 HOH   A O   1 
HETATM 5670 O O   . HOH   E 4 .   ? -36.34014  -22.04826 -109.20909 1.000 15.51613  ? 541 HOH   A O   1 
HETATM 5671 O O   . HOH   E 4 .   ? -47.34491  -18.90830 -88.74147  1.000 36.80684  ? 542 HOH   A O   1 
HETATM 5672 O O   . HOH   E 4 .   ? -16.58364  -30.01040 -110.26944 1.000 17.79642  ? 543 HOH   A O   1 
HETATM 5673 O O   . HOH   E 4 .   ? -25.30528  -14.82246 -128.49663 1.000 36.47321  ? 544 HOH   A O   1 
HETATM 5674 O O   . HOH   E 4 .   ? -41.82383  -10.85733 -118.26236 1.000 16.79988  ? 545 HOH   A O   1 
HETATM 5675 O O   . HOH   E 4 .   ? -40.18142  -7.06723  -111.44904 1.000 24.96903  ? 546 HOH   A O   1 
HETATM 5676 O O   . HOH   E 4 .   ? -15.01026  -23.92133 -127.95485 1.000 39.16024  ? 547 HOH   A O   1 
HETATM 5677 O O   . HOH   E 4 .   ? -29.59312  -25.58601 -90.22094  1.000 33.58914  ? 548 HOH   A O   1 
HETATM 5678 O O   . HOH   E 4 .   ? -21.64330  -13.26660 -110.35820 1.000 33.33906  ? 549 HOH   A O   1 
HETATM 5679 O O   . HOH   E 4 .   ? -51.40240  -30.93472 -107.78454 1.000 34.92640  ? 550 HOH   A O   1 
HETATM 5680 O O   . HOH   E 4 .   ? -22.35654  -13.94030 -108.03845 1.000 24.80428  ? 551 HOH   A O   1 
HETATM 5681 O O   . HOH   E 4 .   ? -33.64574  -9.67949  -124.51261 1.000 33.45048  ? 552 HOH   A O   1 
HETATM 5682 O O   . HOH   E 4 .   ? -47.59255  1.54260   -113.13611 1.000 39.27857  ? 553 HOH   A O   1 
HETATM 5683 O O   . HOH   E 4 .   ? -12.74924  -21.36211 -103.55503 1.000 30.56492  ? 554 HOH   A O   1 
HETATM 5684 O O   . HOH   E 4 .   ? -50.89079  -16.46508 -128.49950 1.000 32.31157  ? 555 HOH   A O   1 
HETATM 5685 O O   . HOH   E 4 .   ? -10.76220  -24.54445 -125.21732 1.000 32.18998  ? 556 HOH   A O   1 
HETATM 5686 O O   . HOH   E 4 .   ? -10.37701  -25.36840 -105.63772 1.000 23.91369  ? 557 HOH   A O   1 
HETATM 5687 O O   . HOH   E 4 .   ? -59.26620  -24.42827 -116.35785 1.000 36.30099  ? 558 HOH   A O   1 
HETATM 5688 O O   . HOH   E 4 .   ? -45.51351  -20.33314 -90.05666  1.000 28.83332  ? 559 HOH   A O   1 
HETATM 5689 O O   . HOH   E 4 .   ? -29.59471  -36.18666 -98.45194  1.000 25.90009  ? 560 HOH   A O   1 
HETATM 5690 O O   . HOH   E 4 .   ? -21.52529  -16.35686 -130.25696 1.000 39.92400  ? 561 HOH   A O   1 
HETATM 5691 O O   . HOH   E 4 .   ? -49.46746  -28.93100 -88.60655  1.000 38.97022  ? 562 HOH   A O   1 
HETATM 5692 O O   . HOH   E 4 .   ? -38.99362  -17.97715 -97.54425  1.000 19.77139  ? 563 HOH   A O   1 
HETATM 5693 O O   . HOH   E 4 .   ? -7.24910   -14.41236 -111.88559 1.000 37.36737  ? 564 HOH   A O   1 
HETATM 5694 O O   . HOH   E 4 .   ? -15.45508  -23.24789 -98.12006  1.000 31.82903  ? 565 HOH   A O   1 
HETATM 5695 O O   . HOH   E 4 .   ? -37.05595  -38.03974 -120.59008 1.000 32.67940  ? 566 HOH   A O   1 
HETATM 5696 O O   . HOH   E 4 .   ? -58.24916  -27.38774 -118.64902 1.000 26.35654  ? 567 HOH   A O   1 
HETATM 5697 O O   . HOH   E 4 .   ? -43.37629  -35.17027 -108.59910 1.000 39.82021  ? 568 HOH   A O   1 
HETATM 5698 O O   . HOH   E 4 .   ? -20.63344  -16.29237 -110.46273 1.000 23.79597  ? 569 HOH   A O   1 
HETATM 5699 O O   . HOH   E 4 .   ? -46.62722  -10.34397 -128.07179 1.000 39.36964  ? 570 HOH   A O   1 
HETATM 5700 O O   . HOH   E 4 .   ? -27.55246  -31.46998 -92.42061  1.000 28.15464  ? 571 HOH   A O   1 
HETATM 5701 O O   . HOH   E 4 .   ? -25.25863  -21.86038 -109.35711 1.000 22.30118  ? 572 HOH   A O   1 
HETATM 5702 O O   . HOH   E 4 .   ? -44.19421  -31.25571 -113.78075 1.000 16.50312  ? 573 HOH   A O   1 
HETATM 5703 O O   . HOH   E 4 .   ? -53.43724  -7.48575  -120.72260 1.000 27.61290  ? 574 HOH   A O   1 
HETATM 5704 O O   . HOH   E 4 .   ? -27.55813  -13.87952 -107.73027 1.000 39.89738  ? 575 HOH   A O   1 
HETATM 5705 O O   . HOH   E 4 .   ? -47.38494  -3.75936  -118.90529 1.000 21.95207  ? 576 HOH   A O   1 
HETATM 5706 O O   . HOH   E 4 .   ? -35.46075  -12.67982 -93.53528  1.000 22.51769  ? 577 HOH   A O   1 
HETATM 5707 O O   . HOH   E 4 .   ? -46.62073  4.19716   -96.09582  1.000 42.38763  ? 578 HOH   A O   1 
HETATM 5708 O O   . HOH   E 4 .   ? -29.06613  -12.14783 -112.91511 1.000 38.14599  ? 579 HOH   A O   1 
HETATM 5709 O O   . HOH   E 4 .   ? -14.05715  -31.05712 -110.47039 1.000 25.33099  ? 580 HOH   A O   1 
HETATM 5710 O O   . HOH   E 4 .   ? -16.46447  -20.17998 -102.75953 1.000 38.50362  ? 581 HOH   A O   1 
HETATM 5711 O O   . HOH   E 4 .   ? -43.92126  5.70365   -95.68281  1.000 45.56085  ? 582 HOH   A O   1 
HETATM 5712 O O   . HOH   E 4 .   ? -43.35717  -21.05067 -134.60170 1.000 35.17788  ? 583 HOH   A O   1 
HETATM 5713 O O   . HOH   E 4 .   ? -21.400    -39.431   -109.365   1.000 27.98675  ? 584 HOH   A O   1 
HETATM 5714 O O   . HOH   E 4 .   ? -35.37976  -19.24447 -87.89099  1.000 35.82550  ? 585 HOH   A O   1 
HETATM 5715 O O   . HOH   E 4 .   ? -34.96029  -30.01765 -91.63432  1.000 27.09349  ? 586 HOH   A O   1 
HETATM 5716 O O   . HOH   E 4 .   ? -49.46009  -30.98775 -110.90136 1.000 32.16793  ? 587 HOH   A O   1 
HETATM 5717 O O   . HOH   E 4 .   ? -7.43419   -29.48898 -121.94694 1.000 35.99159  ? 588 HOH   A O   1 
HETATM 5718 O O   . HOH   E 4 .   ? -19.04104  -26.74994 -94.00508  1.000 21.40628  ? 589 HOH   A O   1 
HETATM 5719 O O   . HOH   E 4 .   ? -53.64865  -30.04366 -114.24171 1.000 32.41238  ? 590 HOH   A O   1 
HETATM 5720 O O   . HOH   E 4 .   ? -15.86399  -35.53336 -114.65448 1.000 37.78169  ? 591 HOH   A O   1 
HETATM 5721 O O   . HOH   E 4 .   ? -30.47744  -20.73616 -94.14094  1.000 39.61080  ? 592 HOH   A O   1 
HETATM 5722 O O   . HOH   E 4 .   ? -44.46700  -13.77876 -87.49193  1.000 35.37338  ? 593 HOH   A O   1 
HETATM 5723 O O   . HOH   E 4 .   ? -30.00195  -37.82965 -99.76367  1.000 36.44234  ? 594 HOH   A O   1 
HETATM 5724 O O   . HOH   E 4 .   ? -34.35613  -11.79044 -97.52790  1.000 29.63726  ? 595 HOH   A O   1 
HETATM 5725 O O   . HOH   E 4 .   ? -59.78813  -16.75604 -123.21899 1.000 36.79990  ? 596 HOH   A O   1 
HETATM 5726 O O   . HOH   E 4 .   ? -6.97642   -25.55789 -110.63254 1.000 38.34073  ? 597 HOH   A O   1 
HETATM 5727 O O   . HOH   E 4 .   ? -43.69616  -13.44602 -132.23339 1.000 35.79810  ? 598 HOH   A O   1 
HETATM 5728 O O   . HOH   E 4 .   ? -19.76331  -16.37978 -115.21211 1.000 27.58984  ? 599 HOH   A O   1 
HETATM 5729 O O   . HOH   E 4 .   ? -29.44280  -36.30378 -94.50206  1.000 33.83114  ? 600 HOH   A O   1 
HETATM 5730 O O   . HOH   E 4 .   ? -28.43542  -44.15435 -114.06861 1.000 24.74276  ? 601 HOH   A O   1 
HETATM 5731 O O   . HOH   E 4 .   ? -52.23866  -11.57573 -126.25611 1.000 27.50474  ? 602 HOH   A O   1 
HETATM 5732 O O   . HOH   E 4 .   ? -7.16618   -16.32547 -119.65989 1.000 41.22395  ? 603 HOH   A O   1 
HETATM 5733 O O   . HOH   E 4 .   ? -39.38641  -28.80682 -129.79885 1.000 38.59917  ? 604 HOH   A O   1 
HETATM 5734 O O   . HOH   E 4 .   ? -53.93285  -22.08678 -91.92353  1.000 34.07687  ? 605 HOH   A O   1 
HETATM 5735 O O   . HOH   E 4 .   ? -47.86394  -19.12981 -129.55437 1.000 27.61645  ? 606 HOH   A O   1 
HETATM 5736 O O   . HOH   E 4 .   ? -18.01229  -36.18820 -121.28308 1.000 38.06281  ? 607 HOH   A O   1 
HETATM 5737 O O   . HOH   E 4 .   ? -35.42003  -14.61374 -131.72733 1.000 34.34444  ? 608 HOH   A O   1 
HETATM 5738 O O   . HOH   E 4 .   ? -38.72977  -36.12759 -101.31032 1.000 28.54606  ? 609 HOH   A O   1 
HETATM 5739 O O   . HOH   E 4 .   ? -13.63011  -33.01761 -112.25743 1.000 36.59812  ? 610 HOH   A O   1 
HETATM 5740 O O   . HOH   E 4 .   ? -38.56476  -4.07555  -116.33658 1.000 39.13554  ? 611 HOH   A O   1 
HETATM 5741 O O   . HOH   E 4 .   ? -52.04749  -14.73650 -126.64415 1.000 46.25749  ? 612 HOH   A O   1 
HETATM 5742 O O   . HOH   E 4 .   ? -51.92638  -31.38330 -110.74166 1.000 39.39697  ? 613 HOH   A O   1 
HETATM 5743 O O   . HOH   E 4 .   ? -59.96271  -1.72287  -110.18009 1.000 42.82413  ? 614 HOH   A O   1 
HETATM 5744 O O   . HOH   E 4 .   ? -8.40344   -21.93195 -108.33879 1.000 31.24204  ? 615 HOH   A O   1 
HETATM 5745 O O   . HOH   E 4 .   ? -27.29501  -23.81200 -128.76683 1.000 40.91159  ? 616 HOH   A O   1 
HETATM 5746 O O   . HOH   E 4 .   ? -28.73697  -17.60939 -97.56183  1.000 38.37682  ? 617 HOH   A O   1 
HETATM 5747 O O   . HOH   E 4 .   ? -59.80442  -12.29556 -109.75409 1.000 35.65987  ? 618 HOH   A O   1 
HETATM 5748 O O   . HOH   E 4 .   ? -56.09167  -7.44145  -120.85614 1.000 38.07294  ? 619 HOH   A O   1 
HETATM 5749 O O   . HOH   E 4 .   ? -57.95968  -9.44196  -95.29276  1.000 37.15341  ? 620 HOH   A O   1 
HETATM 5750 O O   . HOH   E 4 .   ? -53.63384  -32.38625 -96.09759  1.000 45.36122  ? 621 HOH   A O   1 
HETATM 5751 O O   . HOH   E 4 .   ? -60.40860  -25.63031 -114.38002 1.000 34.38152  ? 622 HOH   A O   1 
HETATM 5752 O O   . HOH   E 4 .   ? -50.07309  -0.19148  -110.09260 1.000 26.76718  ? 623 HOH   A O   1 
HETATM 5753 O O   . HOH   E 4 .   ? -51.88946  -32.49696 -101.82255 1.000 31.10803  ? 624 HOH   A O   1 
HETATM 5754 O O   . HOH   E 4 .   ? -52.41448  -18.85411 -130.62761 1.000 40.56573  ? 625 HOH   A O   1 
HETATM 5755 O O   . HOH   E 4 .   ? -39.18906  -7.34465  -108.87667 1.000 20.69076  ? 626 HOH   A O   1 
HETATM 5756 O O   . HOH   E 4 .   ? -7.37398   -30.07575 -111.80564 1.000 43.88498  ? 627 HOH   A O   1 
HETATM 5757 O O   . HOH   E 4 .   ? -31.60421  -14.94321 -97.87596  1.000 24.30884  ? 628 HOH   A O   1 
HETATM 5758 O O   . HOH   E 4 .   ? -17.66956  -37.25175 -113.23444 1.000 40.52790  ? 629 HOH   A O   1 
HETATM 5759 O O   . HOH   E 4 .   ? -17.10012  -36.96532 -110.45808 1.000 36.08147  ? 630 HOH   A O   1 
HETATM 5760 O O   . HOH   E 4 .   ? -46.59350  -12.82660 -85.43765  1.000 33.12717  ? 631 HOH   A O   1 
HETATM 5761 O O   . HOH   E 4 .   ? -5.98809   -27.92804 -120.27004 1.000 39.60806  ? 632 HOH   A O   1 
HETATM 5762 O O   . HOH   E 4 .   ? -36.699    2.526     -116.024   1.000 32.19214  ? 633 HOH   A O   1 
HETATM 5763 O O   . HOH   E 4 .   ? -27.06322  -21.22175 -129.19856 1.000 34.46251  ? 634 HOH   A O   1 
HETATM 5764 O O   . HOH   E 4 .   ? -26.433    -40.922   -101.404   1.000 36.26990  ? 635 HOH   A O   1 
HETATM 5765 O O   . HOH   E 4 .   ? -47.66549  2.40431   -106.78185 1.000 31.92849  ? 636 HOH   A O   1 
HETATM 5766 O O   . HOH   E 4 .   ? -22.81472  -21.65082 -95.67888  1.000 42.01059  ? 637 HOH   A O   1 
HETATM 5767 O O   . HOH   E 4 .   ? -21.714    -39.282   -106.644   1.000 16.89959  ? 638 HOH   A O   1 
HETATM 5768 O O   . HOH   E 4 .   ? -49.40359  -19.85067 -89.59792  1.000 33.23401  ? 639 HOH   A O   1 
HETATM 5769 O O   . HOH   E 4 .   ? -63.75367  -23.39392 -110.61381 1.000 41.71020  ? 640 HOH   A O   1 
HETATM 5770 O O   . HOH   E 4 .   ? -56.32578  -7.12447  -95.01073  1.000 37.64594  ? 641 HOH   A O   1 
HETATM 5771 O O   . HOH   E 4 .   ? -59.38242  -8.70744  -97.31215  1.000 28.53254  ? 642 HOH   A O   1 
HETATM 5772 O O   . HOH   E 4 .   ? -10.37525  -22.88659 -104.43286 1.000 27.02647  ? 643 HOH   A O   1 
HETATM 5773 O O   . HOH   E 4 .   ? -42.01662  -34.59592 -119.90216 1.000 36.30014  ? 644 HOH   A O   1 
HETATM 5774 O O   . HOH   E 4 .   ? -30.05914  -9.99948  -104.04334 1.000 28.49381  ? 645 HOH   A O   1 
HETATM 5775 O O   . HOH   E 4 .   ? -31.37509  -11.90389 -100.01311 1.000 33.39945  ? 646 HOH   A O   1 
HETATM 5776 O O   . HOH   E 4 .   ? -36.73767  -8.59241  -109.52644 1.000 29.93119  ? 647 HOH   A O   1 
HETATM 5777 O O   . HOH   E 4 .   ? -50.37365  -6.21652  -95.93624  1.000 34.64191  ? 648 HOH   A O   1 
HETATM 5778 O O   . HOH   E 4 .   ? -41.80439  -36.04794 -106.30452 1.000 32.68426  ? 649 HOH   A O   1 
HETATM 5779 O O   . HOH   E 4 .   ? -45.14701  -32.32145 -115.68522 1.000 34.44265  ? 650 HOH   A O   1 
HETATM 5780 O O   . HOH   E 4 .   ? -34.96356  -16.34699 -87.90404  1.000 34.31559  ? 651 HOH   A O   1 
HETATM 5781 O O   . HOH   E 4 .   ? -27.56012  -9.27414  -107.78347 1.000 45.84913  ? 652 HOH   A O   1 
HETATM 5782 O O   . HOH   E 4 .   ? -60.18155  -8.85790  -93.57053  1.000 26.33281  ? 653 HOH   A O   1 
HETATM 5783 O O   . HOH   E 4 .   ? -29.55989  -10.57272 -107.14471 1.000 47.91272  ? 654 HOH   A O   1 
HETATM 5784 O O   . HOH   F 4 .   ? -74.92030  -10.23145 -70.35641  1.000 31.46616  ? 401 HOH   B O   1 
HETATM 5785 O O   . HOH   F 4 .   ? -103.18309 -20.20595 -79.88859  1.000 58.26501  ? 402 HOH   B O   1 
HETATM 5786 O O   . HOH   F 4 .   ? -82.69803  -21.11506 -109.89032 1.000 23.16173  ? 403 HOH   B O   1 
HETATM 5787 O O   . HOH   F 4 .   ? -88.47053  -18.64169 -84.12371  1.000 31.81479  ? 404 HOH   B O   1 
HETATM 5788 O O   . HOH   F 4 .   ? -60.21755  -2.77346  -112.68314 1.000 49.59567  ? 405 HOH   B O   1 
HETATM 5789 O O   . HOH   F 4 .   ? -71.31643  -19.50312 -110.13770 1.000 31.52466  ? 406 HOH   B O   1 
HETATM 5790 O O   . HOH   F 4 .   ? -85.80170  -11.69303 -106.73229 1.000 12.60475  ? 407 HOH   B O   1 
HETATM 5791 O O   . HOH   F 4 .   ? -87.07239  9.90712   -99.99319  1.000 40.68074  ? 408 HOH   B O   1 
HETATM 5792 O O   . HOH   F 4 .   ? -78.34506  -13.49528 -74.01484  1.000 36.78602  ? 409 HOH   B O   1 
HETATM 5793 O O   . HOH   F 4 .   ? -94.32659  9.04899   -105.54553 1.000 26.71558  ? 410 HOH   B O   1 
HETATM 5794 O O   . HOH   F 4 .   ? -97.38128  -7.63340  -108.37541 1.000 24.14898  ? 411 HOH   B O   1 
HETATM 5795 O O   . HOH   F 4 .   ? -80.70325  -27.09029 -84.40532  1.000 31.44188  ? 412 HOH   B O   1 
HETATM 5796 O O   . HOH   F 4 .   ? -100.09198 -16.39762 -86.32061  1.000 24.41470  ? 413 HOH   B O   1 
HETATM 5797 O O   . HOH   F 4 .   ? -110.16743 -19.83739 -86.69154  1.000 40.70778  ? 414 HOH   B O   1 
HETATM 5798 O O   . HOH   F 4 .   ? -79.65869  -15.46943 -74.43206  1.000 37.76575  ? 415 HOH   B O   1 
HETATM 5799 O O   . HOH   F 4 .   ? -87.30609  -32.06775 -102.08766 1.000 33.09585  ? 416 HOH   B O   1 
HETATM 5800 O O   . HOH   F 4 .   ? -108.09494 7.51845   -91.21823  1.000 29.21407  ? 417 HOH   B O   1 
HETATM 5801 O O   . HOH   F 4 .   ? -69.41804  -1.25009  -106.78967 1.000 27.60225  ? 418 HOH   B O   1 
HETATM 5802 O O   . HOH   F 4 .   ? -68.20664  -14.79864 -78.12512  1.000 22.13927  ? 419 HOH   B O   1 
HETATM 5803 O O   . HOH   F 4 .   ? -113.07531 0.35619   -92.11235  1.000 20.42626  ? 420 HOH   B O   1 
HETATM 5804 O O   . HOH   F 4 .   ? -97.11839  -7.99193  -111.89320 1.000 27.32235  ? 421 HOH   B O   1 
HETATM 5805 O O   . HOH   F 4 .   ? -90.56799  -4.61506  -100.90469 1.000 13.13363  ? 422 HOH   B O   1 
HETATM 5806 O O   . HOH   F 4 .   ? -78.32400  -25.72727 -85.51485  1.000 32.51557  ? 423 HOH   B O   1 
HETATM 5807 O O   . HOH   F 4 .   ? -107.67617 -7.50593  -110.50134 1.000 38.19626  ? 424 HOH   B O   1 
HETATM 5808 O O   . HOH   F 4 .   ? -73.82681  1.25193   -87.52321  1.000 22.16563  ? 425 HOH   B O   1 
HETATM 5809 O O   . HOH   F 4 .   ? -62.42064  -5.64568  -97.24166  1.000 30.21003  ? 426 HOH   B O   1 
HETATM 5810 O O   . HOH   F 4 .   ? -84.72568  -13.42179 -102.82629 1.000 19.19176  ? 427 HOH   B O   1 
HETATM 5811 O O   . HOH   F 4 .   ? -90.82528  -2.90861  -96.60436  1.000 10.07348  ? 428 HOH   B O   1 
HETATM 5812 O O   . HOH   F 4 .   ? -66.64215  -1.72890  -87.76105  1.000 35.78686  ? 429 HOH   B O   1 
HETATM 5813 O O   . HOH   F 4 .   ? -83.43951  -17.67067 -90.41232  1.000 15.66592  ? 430 HOH   B O   1 
HETATM 5814 O O   . HOH   F 4 .   ? -55.23334  -14.63268 -89.78162  1.000 26.79693  ? 431 HOH   B O   1 
HETATM 5815 O O   . HOH   F 4 .   ? -80.38462  -28.14886 -108.28876 1.000 42.21224  ? 432 HOH   B O   1 
HETATM 5816 O O   . HOH   F 4 .   ? -100.93305 -13.89831 -107.77501 1.000 32.98239  ? 433 HOH   B O   1 
HETATM 5817 O O   . HOH   F 4 .   ? -97.01401  -23.07753 -79.84047  1.000 44.89945  ? 434 HOH   B O   1 
HETATM 5818 O O   . HOH   F 4 .   ? -76.42041  -2.56955  -96.45909  1.000 14.79936  ? 435 HOH   B O   1 
HETATM 5819 O O   . HOH   F 4 .   ? -72.65342  2.40570   -90.46822  1.000 31.19909  ? 436 HOH   B O   1 
HETATM 5820 O O   . HOH   F 4 .   ? -107.39299 -0.92992  -95.52344  1.000 14.48363  ? 437 HOH   B O   1 
HETATM 5821 O O   . HOH   F 4 .   ? -76.97220  -18.33475 -82.90717  1.000 27.01785  ? 438 HOH   B O   1 
HETATM 5822 O O   . HOH   F 4 .   ? -68.14619  -3.82461  -106.49782 1.000 20.28886  ? 439 HOH   B O   1 
HETATM 5823 O O   . HOH   F 4 .   ? -76.85658  -6.16971  -82.23839  1.000 11.45845  ? 440 HOH   B O   1 
HETATM 5824 O O   . HOH   F 4 .   ? -107.94568 -8.12838  -103.81323 1.000 28.23291  ? 441 HOH   B O   1 
HETATM 5825 O O   . HOH   F 4 .   ? -92.27112  -16.82593 -86.90316  1.000 19.11305  ? 442 HOH   B O   1 
HETATM 5826 O O   . HOH   F 4 .   ? -83.94447  -28.29478 -91.27907  1.000 28.58141  ? 443 HOH   B O   1 
HETATM 5827 O O   . HOH   F 4 .   ? -62.07403  -1.38822  -96.53560  1.000 27.54050  ? 444 HOH   B O   1 
HETATM 5828 O O   . HOH   F 4 .   ? -82.33283  -3.39464  -86.20852  1.000 27.72604  ? 445 HOH   B O   1 
HETATM 5829 O O   . HOH   F 4 .   ? -68.96972  -3.32782  -73.40884  1.000 16.36368  ? 446 HOH   B O   1 
HETATM 5830 O O   . HOH   F 4 .   ? -73.61916  -8.53372  -99.07159  1.000 19.37157  ? 447 HOH   B O   1 
HETATM 5831 O O   . HOH   F 4 .   ? -74.67287  -23.13588 -112.67040 1.000 37.86036  ? 448 HOH   B O   1 
HETATM 5832 O O   . HOH   F 4 .   ? -75.03758  -6.85406  -73.83289  1.000 23.30098  ? 449 HOH   B O   1 
HETATM 5833 O O   . HOH   F 4 .   ? -70.90959  -15.67885 -80.48289  1.000 21.82885  ? 450 HOH   B O   1 
HETATM 5834 O O   . HOH   F 4 .   ? -61.80699  -18.96883 -94.68678  1.000 29.05054  ? 451 HOH   B O   1 
HETATM 5835 O O   . HOH   F 4 .   ? -82.13965  -18.98671 -88.30708  1.000 21.71432  ? 452 HOH   B O   1 
HETATM 5836 O O   . HOH   F 4 .   ? -80.53007  -30.72716 -86.43994  1.000 33.82949  ? 453 HOH   B O   1 
HETATM 5837 O O   . HOH   F 4 .   ? -66.08930  -2.47159  -92.39361  1.000 24.02412  ? 454 HOH   B O   1 
HETATM 5838 O O   . HOH   F 4 .   ? -85.54434  -32.80349 -95.66292  1.000 33.31148  ? 455 HOH   B O   1 
HETATM 5839 O O   . HOH   F 4 .   ? -75.60939  -8.09411  -115.79303 1.000 38.16385  ? 456 HOH   B O   1 
HETATM 5840 O O   . HOH   F 4 .   ? -74.77066  -19.17091 -112.79108 1.000 36.86804  ? 457 HOH   B O   1 
HETATM 5841 O O   . HOH   F 4 .   ? -97.84542  -0.59012  -111.75171 1.000 32.94694  ? 458 HOH   B O   1 
HETATM 5842 O O   . HOH   F 4 .   ? -76.28161  -11.85485 -81.11827  1.000 16.79492  ? 459 HOH   B O   1 
HETATM 5843 O O   . HOH   F 4 .   ? -86.51760  -10.25532 -99.70234  1.000 14.70027  ? 460 HOH   B O   1 
HETATM 5844 O O   . HOH   F 4 .   ? -66.55315  -3.29938  -104.27606 1.000 21.39037  ? 461 HOH   B O   1 
HETATM 5845 O O   . HOH   F 4 .   ? -87.46208  0.51215   -97.18488  1.000 11.67480  ? 462 HOH   B O   1 
HETATM 5846 O O   . HOH   F 4 .   ? -69.44437  -5.26546  -81.86603  1.000 22.07686  ? 463 HOH   B O   1 
HETATM 5847 O O   . HOH   F 4 .   ? -102.75343 12.55467  -91.62187  1.000 35.27466  ? 464 HOH   B O   1 
HETATM 5848 O O   . HOH   F 4 .   ? -81.96751  -1.08396  -90.72744  1.000 15.95862  ? 465 HOH   B O   1 
HETATM 5849 O O   . HOH   F 4 .   ? -79.40114  -28.31530 -111.37646 1.000 44.92619  ? 466 HOH   B O   1 
HETATM 5850 O O   . HOH   F 4 .   ? -78.36133  -13.49949 -111.17542 1.000 21.23221  ? 467 HOH   B O   1 
HETATM 5851 O O   . HOH   F 4 .   ? -80.02658  -0.97088  -87.49325  1.000 35.59829  ? 468 HOH   B O   1 
HETATM 5852 O O   . HOH   F 4 .   ? -90.25300  -7.38751  -110.30850 1.000 22.82924  ? 469 HOH   B O   1 
HETATM 5853 O O   . HOH   F 4 .   ? -77.39311  -30.77726 -87.83019  1.000 29.52738  ? 470 HOH   B O   1 
HETATM 5854 O O   . HOH   F 4 .   ? -91.50910  -10.73394 -85.29538  1.000 24.82917  ? 471 HOH   B O   1 
HETATM 5855 O O   . HOH   F 4 .   ? -78.01882  -12.92178 -89.09492  1.000 16.16215  ? 472 HOH   B O   1 
HETATM 5856 O O   . HOH   F 4 .   ? -71.98019  -16.13613 -85.27397  1.000 23.56936  ? 473 HOH   B O   1 
HETATM 5857 O O   . HOH   F 4 .   ? -76.46197  -0.14840  -89.76511  1.000 19.61116  ? 474 HOH   B O   1 
HETATM 5858 O O   . HOH   F 4 .   ? -109.80837 2.66397   -86.55277  1.000 27.00710  ? 475 HOH   B O   1 
HETATM 5859 O O   . HOH   F 4 .   ? -98.96818  -6.24241  -92.04043  1.000 13.85171  ? 476 HOH   B O   1 
HETATM 5860 O O   . HOH   F 4 .   ? -78.02109  -7.45292  -92.56999  1.000 14.44980  ? 477 HOH   B O   1 
HETATM 5861 O O   . HOH   F 4 .   ? -117.57819 -10.35389 -88.67697  1.000 33.33001  ? 478 HOH   B O   1 
HETATM 5862 O O   . HOH   F 4 .   ? -84.58522  -8.60072  -103.36700 1.000 15.76790  ? 479 HOH   B O   1 
HETATM 5863 O O   . HOH   F 4 .   ? -72.579    -12.737   -74.594    1.000 18.55894  ? 480 HOH   B O   1 
HETATM 5864 O O   . HOH   F 4 .   ? -90.82942  -33.87358 -97.78336  1.000 32.69403  ? 481 HOH   B O   1 
HETATM 5865 O O   . HOH   F 4 .   ? -100.00161 -13.76578 -87.31012  1.000 18.34786  ? 482 HOH   B O   1 
HETATM 5866 O O   . HOH   F 4 .   ? -99.22515  -16.11737 -109.89298 1.000 38.56372  ? 483 HOH   B O   1 
HETATM 5867 O O   . HOH   F 4 .   ? -88.31849  -10.39035 -97.62355  1.000 12.93592  ? 484 HOH   B O   1 
HETATM 5868 O O   . HOH   F 4 .   ? -103.66897 1.35550   -106.37737 1.000 15.71928  ? 485 HOH   B O   1 
HETATM 5869 O O   . HOH   F 4 .   ? -71.43880  -24.07295 -92.03620  1.000 25.66670  ? 486 HOH   B O   1 
HETATM 5870 O O   . HOH   F 4 .   ? -94.53397  -12.73142 -111.46835 1.000 35.01589  ? 487 HOH   B O   1 
HETATM 5871 O O   . HOH   F 4 .   ? -70.11991  2.47854   -91.19267  1.000 25.61812  ? 488 HOH   B O   1 
HETATM 5872 O O   . HOH   F 4 .   ? -99.56668  -8.37952  -114.08951 1.000 33.72796  ? 489 HOH   B O   1 
HETATM 5873 O O   . HOH   F 4 .   ? -80.34011  -4.35333  -92.75633  1.000 10.99055  ? 490 HOH   B O   1 
HETATM 5874 O O   . HOH   F 4 .   ? -104.77436 -2.16046  -82.49489  1.000 38.74437  ? 491 HOH   B O   1 
HETATM 5875 O O   . HOH   F 4 .   ? -82.92710  -21.65029 -89.51002  1.000 24.40490  ? 492 HOH   B O   1 
HETATM 5876 O O   . HOH   F 4 .   ? -73.24650  -29.80703 -97.95953  1.000 36.01697  ? 493 HOH   B O   1 
HETATM 5877 O O   . HOH   F 4 .   ? -115.40176 -8.51078  -95.38628  1.000 33.00387  ? 494 HOH   B O   1 
HETATM 5878 O O   . HOH   F 4 .   ? -76.62682  -11.64701 -83.91835  1.000 19.13751  ? 495 HOH   B O   1 
HETATM 5879 O O   . HOH   F 4 .   ? -81.22330  -0.64981  -96.60933  1.000 22.47497  ? 496 HOH   B O   1 
HETATM 5880 O O   . HOH   F 4 .   ? -109.70078 4.39292   -88.80979  1.000 24.11572  ? 497 HOH   B O   1 
HETATM 5881 O O   . HOH   F 4 .   ? -97.68260  -12.57134 -88.33080  1.000 24.45694  ? 498 HOH   B O   1 
HETATM 5882 O O   . HOH   F 4 .   ? -62.84991  -14.53833 -82.46034  1.000 24.86454  ? 499 HOH   B O   1 
HETATM 5883 O O   . HOH   F 4 .   ? -113.26473 3.22307   -89.95519  1.000 35.55757  ? 500 HOH   B O   1 
HETATM 5884 O O   . HOH   F 4 .   ? -71.97097  -26.64994 -99.24267  1.000 31.14764  ? 501 HOH   B O   1 
HETATM 5885 O O   . HOH   F 4 .   ? -102.79076 5.80986   -87.24132  1.000 25.76081  ? 502 HOH   B O   1 
HETATM 5886 O O   . HOH   F 4 .   ? -81.48953  -21.75875 -112.17670 1.000 25.26239  ? 503 HOH   B O   1 
HETATM 5887 O O   . HOH   F 4 .   ? -100.99040 -8.56395  -84.02227  1.000 21.76401  ? 504 HOH   B O   1 
HETATM 5888 O O   . HOH   F 4 .   ? -92.92952  -29.24330 -85.36054  1.000 29.48731  ? 505 HOH   B O   1 
HETATM 5889 O O   . HOH   F 4 .   ? -81.15632  3.74635   -93.01455  1.000 30.68841  ? 506 HOH   B O   1 
HETATM 5890 O O   . HOH   F 4 .   ? -85.97024  -27.52933 -83.86374  1.000 28.97854  ? 507 HOH   B O   1 
HETATM 5891 O O   . HOH   F 4 .   ? -75.35370  -30.51803 -96.26841  1.000 33.13422  ? 508 HOH   B O   1 
HETATM 5892 O O   . HOH   F 4 .   ? -61.51834  -7.33829  -82.52683  1.000 35.61889  ? 509 HOH   B O   1 
HETATM 5893 O O   . HOH   F 4 .   ? -105.07070 -19.42908 -93.07023  1.000 28.23398  ? 510 HOH   B O   1 
HETATM 5894 O O   . HOH   F 4 .   ? -93.51728  4.17917   -98.93989  1.000 21.69656  ? 511 HOH   B O   1 
HETATM 5895 O O   . HOH   F 4 .   ? -116.11831 -11.10650 -85.52214  1.000 24.09038  ? 512 HOH   B O   1 
HETATM 5896 O O   . HOH   F 4 .   ? -83.59657  -3.99003  -81.85813  1.000 35.59597  ? 513 HOH   B O   1 
HETATM 5897 O O   . HOH   F 4 .   ? -73.13703  -3.60679  -72.98392  1.000 24.38585  ? 514 HOH   B O   1 
HETATM 5898 O O   . HOH   F 4 .   ? -78.96652  -1.80114  -97.56065  1.000 19.22377  ? 515 HOH   B O   1 
HETATM 5899 O O   . HOH   F 4 .   ? -97.53820  -3.73155  -85.31212  1.000 20.15378  ? 516 HOH   B O   1 
HETATM 5900 O O   . HOH   F 4 .   ? -95.97651  7.08623   -93.84347  1.000 27.68272  ? 517 HOH   B O   1 
HETATM 5901 O O   . HOH   F 4 .   ? -71.26827  4.69303   -95.64705  1.000 27.32972  ? 518 HOH   B O   1 
HETATM 5902 O O   . HOH   F 4 .   ? -109.882   0.546     -95.157    1.000 20.63885  ? 519 HOH   B O   1 
HETATM 5903 O O   . HOH   F 4 .   ? -79.65100  -33.04005 -94.46601  1.000 26.60349  ? 520 HOH   B O   1 
HETATM 5904 O O   . HOH   F 4 .   ? -76.36108  -8.98976  -84.18071  1.000 18.87835  ? 521 HOH   B O   1 
HETATM 5905 O O   . HOH   F 4 .   ? -102.06842 -19.48810 -108.92145 1.000 34.73473  ? 522 HOH   B O   1 
HETATM 5906 O O   . HOH   F 4 .   ? -85.81583  8.60466   -96.76486  1.000 41.85601  ? 523 HOH   B O   1 
HETATM 5907 O O   . HOH   F 4 .   ? -77.83453  2.78614   -82.16250  1.000 28.51968  ? 524 HOH   B O   1 
HETATM 5908 O O   . HOH   F 4 .   ? -66.57611  -5.42647  -92.54129  1.000 21.54907  ? 525 HOH   B O   1 
HETATM 5909 O O   . HOH   F 4 .   ? -98.03259  -3.36886  -96.49606  1.000 15.61098  ? 526 HOH   B O   1 
HETATM 5910 O O   . HOH   F 4 .   ? -97.52522  -5.42361  -107.03567 1.000 15.41004  ? 527 HOH   B O   1 
HETATM 5911 O O   . HOH   F 4 .   ? -72.32231  -1.97093  -113.57602 1.000 35.47110  ? 528 HOH   B O   1 
HETATM 5912 O O   . HOH   F 4 .   ? -88.68799  7.24979   -94.05397  1.000 44.68719  ? 529 HOH   B O   1 
HETATM 5913 O O   . HOH   F 4 .   ? -115.29601 -5.89186  -79.97814  1.000 39.69833  ? 530 HOH   B O   1 
HETATM 5914 O O   . HOH   F 4 .   ? -82.08099  7.07166   -106.77806 1.000 40.78132  ? 531 HOH   B O   1 
HETATM 5915 O O   . HOH   F 4 .   ? -108.12249 2.35579   -102.32174 1.000 20.39007  ? 532 HOH   B O   1 
HETATM 5916 O O   . HOH   F 4 .   ? -111.58219 -13.42578 -80.89415  1.000 40.74950  ? 533 HOH   B O   1 
HETATM 5917 O O   . HOH   F 4 .   ? -111.18022 -12.29295 -108.31326 1.000 42.82710  ? 534 HOH   B O   1 
HETATM 5918 O O   . HOH   F 4 .   ? -100.56096 -6.31410  -85.26276  1.000 19.43923  ? 535 HOH   B O   1 
HETATM 5919 O O   . HOH   F 4 .   ? -89.19126  1.51303   -90.04504  1.000 17.74457  ? 536 HOH   B O   1 
HETATM 5920 O O   . HOH   F 4 .   ? -91.18390  -23.52862 -83.47040  1.000 37.59078  ? 537 HOH   B O   1 
HETATM 5921 O O   . HOH   F 4 .   ? -111.37785 -9.90642  -80.61591  1.000 34.71097  ? 538 HOH   B O   1 
HETATM 5922 O O   . HOH   F 4 .   ? -57.79106  -12.77611 -91.90141  1.000 30.84236  ? 539 HOH   B O   1 
HETATM 5923 O O   . HOH   F 4 .   ? -93.35596  5.65351   -96.26160  1.000 25.86040  ? 540 HOH   B O   1 
HETATM 5924 O O   . HOH   F 4 .   ? -103.00881 3.71849   -85.68010  1.000 21.28385  ? 541 HOH   B O   1 
HETATM 5925 O O   . HOH   F 4 .   ? -72.45478  -26.81797 -90.88790  1.000 31.76846  ? 542 HOH   B O   1 
HETATM 5926 O O   . HOH   F 4 .   ? -93.07904  6.48304   -93.73557  1.000 29.27593  ? 543 HOH   B O   1 
HETATM 5927 O O   . HOH   F 4 .   ? -90.34707  -27.26742 -105.83679 1.000 35.96173  ? 544 HOH   B O   1 
HETATM 5928 O O   . HOH   F 4 .   ? -69.11820  -10.48176 -113.66683 1.000 27.86719  ? 545 HOH   B O   1 
HETATM 5929 O O   . HOH   F 4 .   ? -95.06192  -22.15329 -107.54354 1.000 35.92560  ? 546 HOH   B O   1 
HETATM 5930 O O   . HOH   F 4 .   ? -58.94486  -14.06634 -84.37469  1.000 38.56366  ? 547 HOH   B O   1 
HETATM 5931 O O   . HOH   F 4 .   ? -76.23972  2.60625   -90.46160  1.000 31.19598  ? 548 HOH   B O   1 
HETATM 5932 O O   . HOH   F 4 .   ? -96.47204  -4.68937  -92.14407  1.000 20.21335  ? 549 HOH   B O   1 
HETATM 5933 O O   . HOH   F 4 .   ? -95.85284  -25.94516 -108.75030 1.000 39.22401  ? 550 HOH   B O   1 
HETATM 5934 O O   . HOH   F 4 .   ? -65.71943  -12.49917 -94.47943  1.000 16.39470  ? 551 HOH   B O   1 
HETATM 5935 O O   . HOH   F 4 .   ? -62.70011  -4.20595  -93.78050  1.000 26.38145  ? 552 HOH   B O   1 
HETATM 5936 O O   . HOH   F 4 .   ? -85.37429  -33.86881 -88.79610  1.000 42.38573  ? 553 HOH   B O   1 
HETATM 5937 O O   . HOH   F 4 .   ? -97.58947  12.24024  -94.29504  1.000 35.97476  ? 554 HOH   B O   1 
HETATM 5938 O O   . HOH   F 4 .   ? -97.18723  1.17966   -86.49560  1.000 22.35156  ? 555 HOH   B O   1 
HETATM 5939 O O   . HOH   F 4 .   ? -104.51300 -12.89525 -79.96946  1.000 39.97840  ? 556 HOH   B O   1 
HETATM 5940 O O   . HOH   F 4 .   ? -85.19816  1.66778   -93.27870  1.000 22.52475  ? 557 HOH   B O   1 
HETATM 5941 O O   . HOH   F 4 .   ? -90.559    -5.333    -87.131    1.000 19.49009  ? 558 HOH   B O   1 
HETATM 5942 O O   . HOH   F 4 .   ? -101.85198 -22.80640 -83.89360  1.000 37.80372  ? 559 HOH   B O   1 
HETATM 5943 O O   . HOH   F 4 .   ? -103.015   -12.477   -116.394   1.000 36.17550  ? 560 HOH   B O   1 
HETATM 5944 O O   . HOH   F 4 .   ? -97.36018  -16.03864 -112.56189 1.000 39.01862  ? 561 HOH   B O   1 
HETATM 5945 O O   . HOH   F 4 .   ? -83.57516  -32.65381 -89.42800  1.000 35.10920  ? 562 HOH   B O   1 
HETATM 5946 O O   . HOH   F 4 .   ? -75.56441  -27.06529 -109.54904 1.000 35.51361  ? 563 HOH   B O   1 
HETATM 5947 O O   . HOH   F 4 .   ? -100.39991 2.92004   -84.45860  1.000 22.47172  ? 564 HOH   B O   1 
HETATM 5948 O O   . HOH   F 4 .   ? -69.09237  -6.82949  -79.59094  1.000 16.03607  ? 565 HOH   B O   1 
HETATM 5949 O O   . HOH   F 4 .   ? -64.08160  -0.95453  -105.10263 1.000 39.97444  ? 566 HOH   B O   1 
HETATM 5950 O O   . HOH   F 4 .   ? -113.06472 -3.90594  -98.74278  1.000 38.58716  ? 567 HOH   B O   1 
HETATM 5951 O O   . HOH   F 4 .   ? -96.36272  2.51592   -110.18796 1.000 35.03086  ? 568 HOH   B O   1 
HETATM 5952 O O   . HOH   F 4 .   ? -79.57703  -18.88763 -86.99631  1.000 23.53420  ? 569 HOH   B O   1 
HETATM 5953 O O   . HOH   F 4 .   ? -84.09695  -9.89910  -112.42793 1.000 26.22825  ? 570 HOH   B O   1 
HETATM 5954 O O   . HOH   F 4 .   ? -63.22546  -20.82004 -97.24402  1.000 28.18998  ? 571 HOH   B O   1 
HETATM 5955 O O   . HOH   F 4 .   ? -93.76310  0.22932   -85.08773  1.000 30.53105  ? 572 HOH   B O   1 
HETATM 5956 O O   . HOH   F 4 .   ? -62.190    -4.655    -80.169    1.000 33.23666  ? 573 HOH   B O   1 
HETATM 5957 O O   . HOH   F 4 .   ? -102.49078 -24.45972 -104.41971 1.000 36.51290  ? 574 HOH   B O   1 
HETATM 5958 O O   . HOH   F 4 .   ? -107.44775 5.62387   -89.30286  1.000 17.88952  ? 575 HOH   B O   1 
HETATM 5959 O O   . HOH   F 4 .   ? -60.82321  3.05441   -103.98195 1.000 44.32909  ? 576 HOH   B O   1 
HETATM 5960 O O   . HOH   F 4 .   ? -77.15528  -14.88407 -84.80552  1.000 23.91937  ? 577 HOH   B O   1 
HETATM 5961 O O   . HOH   F 4 .   ? -71.74906  2.25657   -103.77963 1.000 28.98389  ? 578 HOH   B O   1 
HETATM 5962 O O   . HOH   F 4 .   ? -73.46625  -33.14151 -102.05347 1.000 46.33972  ? 579 HOH   B O   1 
HETATM 5963 O O   . HOH   F 4 .   ? -65.37869  -21.85601 -109.72445 1.000 44.11834  ? 580 HOH   B O   1 
HETATM 5964 O O   . HOH   F 4 .   ? -98.31630  -28.80122 -102.59357 1.000 43.02089  ? 581 HOH   B O   1 
HETATM 5965 O O   . HOH   F 4 .   ? -71.66731  6.33312   -99.07368  1.000 37.30773  ? 582 HOH   B O   1 
HETATM 5966 O O   . HOH   F 4 .   ? -96.61748  11.74795  -96.44068  1.000 29.96111  ? 583 HOH   B O   1 
HETATM 5967 O O   . HOH   F 4 .   ? -72.24440  4.71980   -104.52209 1.000 31.25155  ? 584 HOH   B O   1 
HETATM 5968 O O   . HOH   F 4 .   ? -113.31953 -9.66727  -83.00753  1.000 26.88806  ? 585 HOH   B O   1 
HETATM 5969 O O   . HOH   F 4 .   ? -77.66660  -2.46731  -113.09289 1.000 30.34469  ? 586 HOH   B O   1 
HETATM 5970 O O   . HOH   F 4 .   ? -79.06031  -4.98092  -112.87062 1.000 38.41368  ? 587 HOH   B O   1 
HETATM 5971 O O   . HOH   F 4 .   ? -79.53908  -9.99211  -114.69346 1.000 27.01093  ? 588 HOH   B O   1 
HETATM 5972 O O   . HOH   F 4 .   ? -82.77805  -0.22513  -82.54310  1.000 32.04949  ? 589 HOH   B O   1 
HETATM 5973 O O   . HOH   F 4 .   ? -84.76686  5.80098   -96.34761  1.000 35.24067  ? 590 HOH   B O   1 
HETATM 5974 O O   . HOH   F 4 .   ? -73.79730  -30.02667 -91.17458  1.000 31.18966  ? 591 HOH   B O   1 
HETATM 5975 O O   . HOH   F 4 .   ? -91.82997  12.21602  -99.38751  1.000 39.86288  ? 592 HOH   B O   1 
HETATM 5976 O O   . HOH   F 4 .   ? -87.61888  -10.76156 -94.91288  1.000 18.77503  ? 593 HOH   B O   1 
HETATM 5977 O O   . HOH   F 4 .   ? -70.12665  -1.36780  -81.19316  1.000 33.37256  ? 594 HOH   B O   1 
HETATM 5978 O O   . HOH   F 4 .   ? -77.22111  8.34951   -97.97705  1.000 37.69729  ? 595 HOH   B O   1 
HETATM 5979 O O   . HOH   F 4 .   ? -60.94071  -9.59487  -98.86964  1.000 22.31627  ? 596 HOH   B O   1 
HETATM 5980 O O   . HOH   F 4 .   ? -85.11035  6.73357   -107.37552 1.000 43.26056  ? 597 HOH   B O   1 
HETATM 5981 O O   . HOH   F 4 .   ? -80.63783  -14.53557 -112.94167 1.000 32.44633  ? 598 HOH   B O   1 
HETATM 5982 O O   . HOH   F 4 .   ? -75.57049  -26.20213 -85.73505  1.000 31.32425  ? 599 HOH   B O   1 
HETATM 5983 O O   . HOH   F 4 .   ? -64.48781  0.73257   -90.86297  1.000 31.47173  ? 600 HOH   B O   1 
HETATM 5984 O O   . HOH   F 4 .   ? -104.44185 -15.28642 -81.72258  1.000 21.43829  ? 601 HOH   B O   1 
HETATM 5985 O O   . HOH   F 4 .   ? -93.132    -18.363   -78.644    1.000 29.37784  ? 602 HOH   B O   1 
HETATM 5986 O O   . HOH   F 4 .   ? -112.50559 3.42832   -86.77026  1.000 35.93417  ? 603 HOH   B O   1 
HETATM 5987 O O   . HOH   F 4 .   ? -80.10101  -7.41167  -114.67926 1.000 37.66232  ? 604 HOH   B O   1 
HETATM 5988 O O   . HOH   F 4 .   ? -57.19767  -20.28703 -86.44713  1.000 45.06872  ? 605 HOH   B O   1 
HETATM 5989 O O   . HOH   F 4 .   ? -83.50187  5.39209   -93.82692  1.000 32.57691  ? 606 HOH   B O   1 
HETATM 5990 O O   . HOH   F 4 .   ? -112.05186 -1.03989  -96.44505  1.000 31.25693  ? 607 HOH   B O   1 
HETATM 5991 O O   . HOH   F 4 .   ? -95.073    -17.579   -80.488    1.000 32.43806  ? 608 HOH   B O   1 
HETATM 5992 O O   . HOH   F 4 .   ? -104.65306 -22.94883 -93.36525  1.000 37.88873  ? 609 HOH   B O   1 
HETATM 5993 O O   . HOH   F 4 .   ? -81.91265  -19.66869 -113.59682 1.000 41.47038  ? 610 HOH   B O   1 
HETATM 5994 O O   . HOH   F 4 .   ? -108.87228 -15.14646 -105.66063 1.000 41.27680  ? 611 HOH   B O   1 
HETATM 5995 O O   . HOH   F 4 .   ? -79.52107  -0.02867  -89.74901  1.000 22.19708  ? 612 HOH   B O   1 
HETATM 5996 O O   . HOH   F 4 .   ? -94.276    -20.032   -76.496    1.000 42.72162  ? 613 HOH   B O   1 
HETATM 5997 O O   . HOH   F 4 .   ? -104.22392 -22.39805 -90.98261  1.000 50.94806  ? 614 HOH   B O   1 
HETATM 5998 O O   . HOH   F 4 .   ? -67.13902  -3.62304  -109.08426 1.000 37.67402  ? 615 HOH   B O   1 
HETATM 5999 O O   . HOH   F 4 .   ? -95.25666  4.44117   -109.25036 1.000 39.01587  ? 616 HOH   B O   1 
HETATM 6000 O O   . HOH   F 4 .   ? -57.33851  -9.73999  -85.27730  1.000 39.87610  ? 617 HOH   B O   1 
HETATM 6001 O O   . HOH   F 4 .   ? -81.09226  -33.84413 -96.30501  1.000 32.69437  ? 618 HOH   B O   1 
HETATM 6002 O O   . HOH   F 4 .   ? -105.89878 -19.97993 -79.91138  1.000 46.93160  ? 619 HOH   B O   1 
HETATM 6003 O O   . HOH   F 4 .   ? -104.35748 -17.89140 -79.44626  1.000 34.35266  ? 620 HOH   B O   1 
HETATM 6004 O O   . HOH   F 4 .   ? -78.61871  -17.08169 -85.54792  1.000 35.14563  ? 621 HOH   B O   1 
HETATM 6005 O O   . HOH   F 4 .   ? -79.72979  -19.19942 -83.83682  1.000 35.16642  ? 622 HOH   B O   1 
HETATM 6006 O O   . HOH   F 4 .   ? -54.00113  -16.91639 -90.25689  1.000 24.52052  ? 623 HOH   B O   1 
HETATM 6007 O O   . HOH   F 4 .   ? -112.78627 6.03679   -90.12200  1.000 48.69640  ? 624 HOH   B O   1 
HETATM 6008 O O   . HOH   F 4 .   ? -87.25298  8.54306   -107.73549 1.000 42.07848  ? 625 HOH   B O   1 
HETATM 6009 O O   . HOH   F 4 .   ? -106.569   -20.139   -107.070   1.000 42.27428  ? 626 HOH   B O   1 
HETATM 6010 O O   . HOH   F 4 .   ? -113.82748 -1.16608  -94.03984  1.000 24.92002  ? 627 HOH   B O   1 
HETATM 6011 O O   . HOH   F 4 .   ? -74.94696  9.10405   -99.27578  1.000 38.34707  ? 628 HOH   B O   1 
HETATM 6012 O O   . HOH   F 4 .   ? -68.90191  0.59722   -104.96930 1.000 33.92499  ? 629 HOH   B O   1 
HETATM 6013 O O   . HOH   F 4 .   ? -96.55141  -1.83279  -84.11023  1.000 34.47410  ? 630 HOH   B O   1 
HETATM 6014 O O   . HOH   F 4 .   ? -83.09596  1.36224   -91.31748  1.000 23.89631  ? 631 HOH   B O   1 
HETATM 6015 O O   . HOH   F 4 .   ? -83.95412  -34.36092 -91.74668  1.000 39.64221  ? 632 HOH   B O   1 
HETATM 6016 O O   . HOH   F 4 .   ? -85.89842  3.99252   -92.58680  1.000 29.19011  ? 633 HOH   B O   1 
HETATM 6017 O O   . HOH   F 4 .   ? -66.32217  -14.63484 -80.80227  1.000 37.27798  ? 634 HOH   B O   1 
HETATM 6018 O O   . HOH   F 4 .   ? -78.85189  -13.16101 -86.33108  1.000 25.34823  ? 635 HOH   B O   1 
HETATM 6019 O O   . HOH   F 4 .   ? -89.75611  -11.46033 -112.92348 1.000 34.95737  ? 636 HOH   B O   1 
HETATM 6020 O O   . HOH   F 4 .   ? -72.38414  5.51646   -93.19055  1.000 37.48847  ? 637 HOH   B O   1 
HETATM 6021 O O   . HOH   F 4 .   ? -62.68788  -7.87796  -94.40155  1.000 22.25177  ? 638 HOH   B O   1 
HETATM 6022 O O   . HOH   F 4 .   ? -60.23168  0.29375   -111.37451 1.000 47.53720  ? 639 HOH   B O   1 
HETATM 6023 O O   . HOH   F 4 .   ? -67.11123  -19.66010 -85.22939  1.000 32.75923  ? 640 HOH   B O   1 
HETATM 6024 O O   . HOH   F 4 .   ? -63.83615  -6.36143  -92.54798  1.000 20.59533  ? 641 HOH   B O   1 
HETATM 6025 O O   . HOH   F 4 .   ? -89.36244  -8.67887  -112.74358 1.000 33.56882  ? 642 HOH   B O   1 
HETATM 6026 O O   . HOH   F 4 .   ? -105.78224 6.48508   -87.17104  1.000 31.14996  ? 643 HOH   B O   1 
# 
